bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN GETARAN LENGAN-TANGAN DENGAN KELUHAN CARPAL TUNNEL SYNDROME PADA PEKERJA HOME INDUSTRY PANDAI BESI DI KECAMATAN SOKOBANAH SAMPANG
Authors: QORIBULLAH FATHUL
Published: March 2020

Carpal Tunnel Syndrome (CTS) adalah salah satu penyakit akibat kerja. CTS disebabkan oleh disfungsi saraf median yang terjadi karena peningkatan tekanan di terowongan karpal. Tujuan penelitian ini adalah untuk menganalisis hubungan antara keluhan getaran lengan-tangan Carpal Tunnel Syndrome di pandai besi Industri Rumah Tangga di Kabupaten Sokobanah. Desain penelitian dengan pendekatan Cross-Sectional. Populasi dan sampel yang diperoleh adalah semua pekerja pandai besi Industri Rumah Tangga di Kabupaten Sokobanah dengan 33 orang. Teknik pengambilan sampel menggunakan sampel jenuh adalah bahwa populasi memiliki kesempatan yang sama untuk dijadikan sampel. Variabel yang diteliti adalah getaran lengan-lengan dan keluhan Carpal Tunnel Syndrome. Instrumen penelitian yang digunakan adalah lembar kuesioner dan alat ukur (Vibration Meter). Analisis data menggunakan uji korelasi Spearman. Hasil penelitian menunjukkan bahwa sebagian besar (75,8%) terkena getaran tidak nyaman, sebagian besar (63,6%) memiliki keluhan CTS parah dan ada hubungan yang signifikan antara getaran lengan-tangan dan keluhan Carpal Tunnel Syndrome  (p  =  0,01).  Disimpulkan  bahwa  paparan  getaran  lengan  yang  lebih  tinggi  dapat meningkatkan keluhan Carpal Tunnel Syndrome pada pekerja Home Industri pandai besi di Kabupaten Sokobanah. Direkomendasikan bagi Industri Rumah Tangga untuk meningkatkan pengawasan pekerja pandai besi melalui evaluasi kinerja dengan aspek kehati-hatian dalam bekerja dan menggunakan Alat Pelindung Diri (APD) untuk pekerja.
PERBANDINGAN KADAR FLAVONOID DAN VITAMIN C PADA INFUSED WATER GOJI BERRY (Lycium barbarum) DAN AIR NABEEZ KURMA (Phoenix dactylifera L.)
Authors: Putri Endah Budi Permana , Putri Fildzah Karunia , Sulaiha Siti
Published: March 2020

Latar Belakang: Air merupakan makronutrien yang berperan penting bagi kehidupan manusia, namun beberapa penelitian mendapatkan bahwa konsumsi cairan masih kurang dari 2 Liter per hari. Apabila tubuh tidak mendapatkan cukup air, atau kehilangan air sebanyak 5% saja dari berat badannya maka tubuh akan mengalami dehidrasi. Salah satu cara untuk meningkatkan konsumsi cairan yaitu dengan membuat alternatif minuman selain air putih, seperti infused water dari goji berry dan kurma.Tujuan: Menganalisis perbandingan kadar flavonoid dan vitamin C pada infused water goji berry dan air nabeez kurma. Metode: Jenis penelitian ini adalah eksperimental. Infused water goji berry dibuat dengan cara merendam 15 g goji berry kering dalam 300 ml air selama 12 jam, sedangkan air nabeez kurma dibuat dengan cara merendam 15 g daging kurma ajwa dalam 300 ml air selama 12 jam dan 24 jam. Analisis statistik yang digunakan yaitu uji One Way Anova. Hasil: Ada perbedaan rata-rata kadar flavonoid dimana kadar flavonoid tertinggi terdapat pada infused water goji berry (40,44 mg/L), air nabeez kurma perendaman 24 jam (8,08 mg/L), dan air nabeez kurma perendaman 12 jam (6,83 mg/L). Ada perbedaan rata-rata kadar vitamin C pada infused water goji berry (5,28 mg/ml) dan air nabeez kurma perendaman 12 dan 24 jam (2,64 mg/ml). Kesimpulan: Kadar flavonoid dan vitamin C infused water goji berry lebih tinggi daripada air nabeez kurma perendaman 12 dan 24 jam.
HUBUNGAN UMUR DAN JUMLAH ANAK TERHADAP PENGGUNAAN METODE KONTRASEPSI DI PUSKESMAS BULAK BANTENG SURABAYA
Authors: Dewiyanti Nur
Published: March 2020

Kontrasepsi merupakan salah satu alat yang dapat dilakukan masyarakat untuk membantu mengendalikan lajunya pertambahan penduduk. Jumlah pengguna metode kontrasepsi jangka panjang masih rendah dibandingkan non metode kontrasepsi jangka panjang yang peminatnya masih tinggi. Tujuan dari penelitian ini adalah menganalisis faktor yang berpengaruh terhadap penggunaan metode kontrasepsi di wilayah kerja Puskesmas Bulak Banteng Surabaya. Penelitian ini bersifat analitik observasional, dengan desain menurut waktumya bersifat cross sectional study. Subjek diambil dari populasi dengan cara simple random sampling. Penelitian ini menganalisis pengaruh faktor setiap variabel bebas terhadap penggunaan metode kontrasepsi jangka panjang. Populasi dalam penelitian ini adalah semua wanita PUS (Pasangan Usia Subur) berusia 15-49 tahun yang merupakan akseptor KB metode kontrasepsi jangka panjang dan non metode kontrasepsi jangka panjang yang bertempat tinggal di wilayah kerja Puskesmas Bulak Banteng Surabaya. Variabel bebas yang digunakan adalah usia dan jumlah anak yang dimiliki responden. Variabel terikat yang digunakan adalah penggunaan metode kontrasepsi. Didapatkan jumlah sebanyak 94 responden. Data yang telah terkumpul dianalisis secara univariat dan bivariat. Hasil uji bivariat menunjukkan bahwa usia responden tidak memiliki hubungan dengan penggunaan metode konrasepsi (p=0,074 > α=0,05) sedangkan pada jumlah anak memiliki hubungan yang signifikan dengan penggunaan metode kontrasepsi (p=0,048 < α=0,05).
Motherhood after the age of 35 in Poland
Authors: Rybińska Anna
Published: March 2020

Postponing motherhood is a widespread phenomenon across developed countries, however only few studies look into very late motherhood in post-socialist countries using individual level data. In this study, I look at the context of the first childbirth in Poland in the midst of the political transformation of 1989. Employing sequence analysis I reconstructed life trajectories of women who experienced the transition to adulthood during the late 1980’s and the early 1990’s and have just completed their fertility histories. Individual data from the 2011 GGS-PL and the 2011 FAMWELL Survey were used. Comparing paths of mothers’ lives, I searched for differences in educational, professional and conjugal careers between women who gave birth before the age of 30 and after the age of 35. The results show how various life careers crisscross over the life course leading women to late motherhood.
Estymacja prawdopodobieństw przejścia między stanami zdrowia osóbw wieku 50 lat i więcej w Polsce w modelu wielostanowym
Authors: Łątkowski Wojciech
Published: March 2020

Poland will experience advanced population ageing driven by improvements in longevity, low fertility and retirement of baby boom cohorts. Given the higher morbidity prevalence observed at older ages, the demand for the elderly care is expected to increase.

The study focuses on the dynamics of health of people aged 50 and over in Poland. We want to verify how the risks of the health status change are shaped over age and what the impact of sex is.

The empirical analysis provides a description of a non-parametric multi-state model for transitions in health. The age- and sex-specific health transition rates and probabilities are estimated based on the European Union Statistics on Income and Living Conditions (EU-SILC) panel data for the years 2008–2011.

The results confirm the well-known regularities in research on health: the risk of being unhealthy is increasing with age, while the probability of recovery is decreasing. Women have a higher risk of the onset of disability than men, whereas recovery to health is similar for men and women.
Estimation of fertility in Poland and of Polish born women in the United Kingdom
Authors: Gołata Elżbieta
Published: March 2020

The aim of research presented in the paper is to explore the comparison of Total Fertility Rates of Polish women in England and Wales, with the rates for Polish women who are residents in Poland. Population censuses in Poland and the United Kingdom in 2011 provide information for such comparisons and show higher fertility rates of Polish women abroad than in Poland.

Two specific questions were investigated. The first one is the question of the number of children born in Poland. It was observed that the number estimated on the basis of census data was not consistent with birth records in the register. The second question concerns the number of the usually resident population in Poland. We provide quality assessment of 2011 population census in Poland, estimates of actual and usually resident population. Based on thorough evaluation, a correction of the population estimates is proposed (RAF). Due to non-response and data omissions, the idea of Small Domain Estimation is applied with two a priori age and sex distributions: from the Polish Census Survey and upon the UK census.

Fertility in Poland is estimated with regard to usually resident population published on the Census Hub, our RAF estimates and LFS data. The estimates of women at reproductive age differ for over 495,000, what cause certain discrepancies in TFR. Additionally we analyse changes in timing of birth and provide tempo adjusted TFR. The paper shows consequences of population estimates for measuring fertility. It was found that depending on the population estimates TFR in Poland differs from 1.31 for actual population to 1.45 for RAF estimates and 1.63 for tempo-adjusted TFR.

Via detailed empirical examination of the usually resident population estimates in Poland we show inconsistencies resulting from the flexibility in interpretation of definitions given by EU 1260/2013 and specific regulations of individual countries.
Uwarunkowania skłonności do palenia papierosów. Wyniki modelowania równań strukturalnych
Authors: Czaderny Krzysztof
Published: March 2020

According to the age-period-cohort projection of lung cancer incidence (ICD-10 codes C33-C34), smoking prevention will be crucial for both men and women longevity. Lung cancer remains the main cancer cause of death among males in Poland. In 2014 the number of deaths in Poland caused by lung cancer among men was more than twice as high as for women. The study is focused on identification of attitudes influencing the propensity to smoke, which is performed by structural equation modelling (SEM) based on weighted least squares means and variance adjusted (WLSMV) estimation. Good fit of the presented models is demonstrated by RMSEA, NNFI and CFI values. Reliability of scales is assessed by ordinal alpha and ordinal theta coefficients.

Commitment to learning in childhood exhibits the highest standardized effect on propensity to smoke, which is an argument for youth smoking prevention. Structural equation model was estimated for men and women separately because of gender differences in smoking determinants. A strong character, individualism and self-reliance are the factors, which increase smoking propensity among males. These can be treated as features of masculinity and are not statistically important determinants of being a smoker for females. Depressive disorders, being a victim of violence as adults are statistically significant determinants of smoking among women.
Pomiar rektangularyzacji krzywej przeżycia – stan wiedzy i analiza wyników
Authors: Wnuk Agata
Published: March 2020

This article is a result of a methodological literature review concerning the compression of mortality and rectangularization of the survival curve concepts. It aims to identify the current state of knowledge – key definitions, existing tools of measurement and analysis of empirical research conducted so far in Europe. The process of gathering and selecting scientific literature is precisely described so that one can easily understand the obtained knowledge synthesis and possibly improve further research. The first part of this paper includes definitions of the rectangularization of the survival curve, its dimensions, and related terminology. Then, 26 measures and indicators of the phenomenon, found in existing scientific literature, are described individually and gathered in a comparative table. Finally, the results of reviewing empirical research of 11 European countries are presented: Sweden, France, Switzerland, Great Britain, the Netherlands, Italy, Finland, Denmark, Norway, Spain, and Poland. The results are further discussed on the example of France. The analysis shows that some of the rectangularization measures are still rarely used empirically, some being only theoretically formulated. Moreover, these studies have small to none representation of some European countries. As a result of this literature review, new interesting paths for further research are formulated.
Life expectancy and lifespan inequality: a perfect linear correlation? Analysis of the relationship with a particular emphasis on the case of countries going through the life expectancy stagnation period
Authors: Potyra Maciej
Published: March 2020

In recent years in demography there has been a growing discussion about the relationship between life expectancy and lifespan inequality. It appears that in the long run this relationship tends to be strongly linear – countries with the longest life expectancy are also the most equal. This article takes a closer look at countries that went through long periods of life expectancy stagnation and shows that during those times they also experienced a reduction in inequality, mainly due to a large decrease in infant mortality. However, if only adult mortality is taken into account inequality was stagnating or even rising in many cases. Particularly interesting is the fact that a similar pattern of the relationship between life expectancy and lifespan inequality was observed both in Eastern or Western Europe.
Визначення параметрів горизонтальних проекцій крон дерев за матеріалами зйомки безпілотними літальними апаратами
Authors: Bidolakh D. I. , Bilous A. M. , Kuziovych V. S.
Published: March 2020

Опрацьовано можливість використання результатів зйомки дерев із безпілотного літального апарата (БПЛА) DJI Phantom 4 для визначення горизонтальних проекцій їхніх крон. Встановлено, що такий підхід дає змогу підвищувати якість, точність і швидкість визначення площі горизонтальної проекції крони за актуальним картографічним матеріалом, опрацьованим у середовищі ГІС. Апробацію запропонованого способу проведено на базі лісових масивів і садово-паркових насаджень міста Бережани в Тернопільській області шляхом порівняння результатів, отриманих з використанням цього підходу й традиційним способом вимірювання. Виявлено, що запропонований спосіб дає можливість отримувати результати високої точності внаслідок кращої передачі конфігурації крони фотографічними матеріалами БПЛА-зйомки в порівнянні з традиційними вимірювальними методами, які дають інформацію лише про її радіуси. Такий підхід дає змогу визначати горизонтальні проекції крон дерев за допомогою програмних засобів із мінімізацією трудомістких польових робіт і створює умови для збереження інформації в цифровому форматі. Він може бути використаний для потреб лісо- та парковпорядкування, вивчення взаємодії деревних рослин у насадженні, визначення зімкнутості деревостану, проведення інвентаризації зелених насаджень та інших наукових досліджень.
Соснові деревостани лісостепу Харківщини: продуктивність і природне поновлення
Authors: Garmash A. V.
Published: March 2020

Наведено матеріали досліджень соснових лісостанів Лісостепу Харківської області. Встановлено основні лісівничо-таксаційні показники деревостанів в основних типах лісорослинних умов регіону дослідження за даними пробних площ. Проаналізовано дані стосовно повноти, запасу, середніх діаметрів і висот відповідно до класів віку. Наведено дані постійних пробних площ у ДП «Скрипаївське НДЛГ» та ділянок інтенсивного моніторингу в ДП «Жовтневе ЛГ» і НПП «Слобожанський». Показано динаміку таксаційних показників на ділянках; особливу увагу звертали на запаси деревостанів. Зроблено опис надґрунтового покриву ділянок за типами лісу, визначено характер розміщення рослин за площею та частку проективного покриття. Окремо встановлено співвідношення покриття на пробних площах трав, лишайників і мохів, показано його залежність від типу лісу. Проаналізовано дані щодо природного поновлення, вказано його густоту, характер розміщення, середні показники висот і діаметрів та їхню залежність від розміщення на ділянці, визначено категорію життєздатності підросту.
Реакція радіального приросту Pinus sylvestris L. на зміну клімату в насадженнях Лівобережного Лісостепу
Authors: Koval I. M. , Voronin V. O.
Published: March 2020

Досліджено особливості реакції радіального приросту сосни звичайної (Pinus sylvestris L.) на зміну клімату в середньовіковому чистому сосновому насадженні Лівобережного Лісостепу. Використано стандартні дендрохронологічні методики. Виявлено роки мінімального приросту: 1975, 1987 та 2013, що обумовлено високими середньорічними температурами 1975 та 2013 рр. і низькими зимовими температурами 1987 р. Роки максимального приросту (1944, 1957, 1978 та 2004.) відзначалися оптимальним співвідношенням тепла й вологи. Виявлено взаємозв’язки між радіальним приростом сосни й опадами та температурами за два періоди – 1960–1992 та 1985–2017 рр. У другому періоді дерева стали більш чутливими до погодних стрес-чинників унаслідок потепління, про що свідчать результати кореляційного аналізу та функції відгуку. Збільшилася кількість значущих зв’язків між радіальним приростом і кліматичними чинниками в другому періоді внаслідок ослаблення насадження, викликаного зміною клімату. Посилився негативний вплив температур попереднього року та вегетаційного періоду поточного року на радіальний приріст сосни.
Особливості морфологічних і біометричних характеристик репродуктивних органів сосни звичайної різної стійкості в насадженнях, уражених кореневою губкою
Authors: Dyshko V. A. , Ustsky I. M. , Mikhaylichenko A. A.
Published: March 2020

Висвітлено результати дослідження морфологічних та біометричних характеристик дерев сосни звичайної різного санітарного стану в уражених кореневою губкою насадженнях V і VI класів віку. В осередках усихання відібрано дерева без ознак ослаблення («стійкі») та з ознаками хвороби («хворі»), а в міжосередковому просторі – середні за таксаційними показниками дерева І категорії санітарного стану – контроль. Оцінювали якісні й кількісні характеристики шишок, насіння, крилаток (забарвлення, розміри, форму та масу). Розміри генеративних органів сосни з підвищеною резистентністю виявилися більшими, ніж у дерев із ознаками хвороби та контрольних, що є наслідком адаптації дерева до відкритого простору прогалини на тлі розвитку патологічних процесів і з генетичними особливостями сосни пов’язано мало. Дерева з підвищеною резистентністю в осередках усихання характеризуються суттєво більшою варіабельністю показників діаметра (Cv = 21,2…27,4 %), ніж «хворі» (Cv = 8,9…12,1 %).
Продуктивність і стан насаджень cосни чорної австрійської (Pinus nigra var. austriaca Asch. et Gr.) у центральній та північно-східній частинах України
Authors: Tereshchenko L. I. , Los S. A. , Petrenko M. I. , Samoday V. P.
Published: March 2020

Наведені результати обстеження насаджень сосни чорної австрійської в Кіровоградській, Харківській і Сумській областях у 2017 та 2018 рр. В умовах Лісостепу та Степу досліджено 4 деревостани віком 27–117 років, лісові культури 27-річного віку є потомством найстарішого з обстежених деревостанів. Оцінювання насаджень проведено за ростом, якістю стовбурів, станом, а також показниками репродукції. Для комплексного оцінювання деревостанів використано 3-балову шкалу. В усіх обстежених насадженнях сосна чорна поступається сосні звичайній за висотою, але у 2 із 5 випадків перевищує її за діаметром; характеризується стовбурами більшої якості та кращім станом. За результатами комплексного оцінювання сосна чорна австрійська набрала більшу або таку саму кількість балів, як і сосна звичайна. Підтверджено перспективність застосування сосни чорної для створення лісових і захисних насаджень на еродованих ґрунтах. У разі помірного рекреаційного навантаження вона спроможна виконувати меліоративні функції, а завдяки своїй високій декоративності придатна для садово-паркового будівництва.
Uso da hipotermia induzida após parada cardiorrespiratória
Authors: Silva Ionara , Silva Joyce Carolynne , Lima Karen Rayara Bezerra , Dantas Daniele Vieira , Dantas Rodrigo Assis Neves , Ribeiro Maria do Carmo de Oliveira
Published: March 2020

Introdução: A parada cardiorrespiratória é definida como a cessação abrupta da atividade mecânica do coração. Os indiví­duos que conseguem sobreviver podem adquirir danos neurológicos irreversí­veis. A indução da hipotermia visa a diminuição do metabolismo cerebral, limitação da lesão miocárdica e sistêmica. Objetivo: Identificar as informações recentes e as principais medidas a serem tomadas durante o uso de hipotermia induzida em ambiente hospitalar após ocorrência de parada cardiorrespiratória. Métodos: Revisão da literatura cientí­fica do tipo integrativa empí­rica. A busca foi realizada em outubro de 2017, na Biblioteca Virtual em Saúde, bases de dados da Literatura Latino-Americana e do Caribe de Informação em Ciências da Saúde; na Medical Literature Analysis and Retrieval System Online, Scientific Electronic Library Online, além de buscas realizadas no Pubmed. Resultados: Os estudos selecionados trazem diversas contribuições sobre o uso da hipotermia induzida em ambiente hospitalar. Estes foram divididos nas seguintes categorias de análise: Desfecho neurológico e fatores predisponentes de resultados após a HT, Medidas eficazes de cuidado durante a HT e, por fim, os Efeitos da hipertermia de rebote após a HT. Conclusão: Os resultados demonstraram a necessidade da atualização frequente dos profissionais sobre o tema, com o intuito de qualificar a assistência, baseando-se em evidências.Palavras-chave: parada cardí­aca, reanimação cardiopulmonar, hipotermia induzida, emergências, cuidados crí­ticos.
Avaliação de trabalhadores rurais do interior de Rondônia quanto ao uso de agrotóxicos
Authors: Coelho Aline de Souza , Custódio Daiany Cristina Gil Glioli , Alves Hosana Nolasco dos Santos , Pereira Giselle Cristina Andrade , De Novaes Valéria Pinheiro , Amaral Pâmella Polastry Braga
Published: March 2020

Os agrotóxicos são agentes quí­micos utilizados para maximizar o processo de produção agrí­cola. Porém a sua utilização sem controle adequado, treinamento e utilização de equipamentos de proteção individual colocam em risco a saúde de todos expostos a estes produtos. Tendo em vista a quantidade de agrotóxicos consumidos na região do estudo, o objetivo é verificar a exposição a agrotóxicos em produtores rurais do interior de Rondônia. A pesquisa foi realizada com 94 produtores rurais do municí­pio de Ji-Paraná, onde receberam uma avaliação clí­nico-laboratorial. Observou-se que a população em sua maioria realiza a aplicação de agrotóxicos de forma errônea, sem uso de equipamentos de proteção individual (EPIs), além de terem sido encontradas elevadas concentrações de diversos produtos quí­micos altamente tóxicos. Os produtores em sua maioria se enquadram com sinais de intoxicação em exames laboratoriais alterados e sinais e sintomas caracterí­sticos. Estes dados demonstram a importância da fiscalização da exposição desses produtores aos agrotóxicos, bem como seu treinamento no manuseio dos produtos quí­micos, no intuito de redução das repercussões apresentadas e de possí­vel ocorrência.Palavras-chave: agroquí­micos, envenenamento, sinais e sintomas.
Sec22b determines Weibel-Palade body length by controlling anterograde ER-Golgi transport
Authors: Ellie Karampini  , Petra E. Bürgisser  , Jenny Olins  , Aat A. Mulder  , Carolina R. Jost  , Dirk Geerts  , Jan Voorberg  , Ruben Bierings
Published: March 2020

Von Willebrand factor (VWF) is a multimeric hemostatic protein that is synthesized in endothelial cells, where it is stored for secretion in elongated secretory organelles, so-called Weibel-Palade bodies (WPBs). Hemostatic activity of VWF is strongly tied to WPB length, but how endothelial cells control the dimensions of their WPBs is unclear. In this study we used a targeted shRNA screen to identify the longin-SNARE Sec22b as a novel determinant of WPB size and VWF trafficking. We found that Sec22b depletion resulted in loss of the typically elongated WPB morphology along with disintegration of the Golgi and dilation of rough ER (rER) cisternae. This was accompanied by reduced proteolytic processing of VWF, accumulation of VWF in the dilated rER and reduced basal and stimulated VWF secretion. Our data demonstrate that the elongation of WPBs, and thus adhesive activity of its cargo VWF, is determined by the rate of anterograde transport between ER and Golgi, which depends on Sec22b-containing SNARE complexes.
Association News - 2019
Authors: - -
Published: March 2020

Abstract not available

Bang Med J (Khulna) 2019; 52 : 46
Hypertrophic Cardiomyopathy: The Molecular Genetics
Authors: Masum Md Mohiuddin , Sayeef Md Abdullah Al , Shahrear Rayhan , Banik Devjani , Biswas Gonopati , Yesmin Zinnat Ara
Published: March 2020

Hypertrophic Cardiomyopathy (HCM) is the common monogenic form familial pathological cardiac hypertrophy. HCM is an important cause of sudden cardiac death in the young adult and a major cause of morbidity in the elderly. We discuss here the molecular genetics and recent advances in the molecular genetics of HCM. HCM became the first cardiac disease for which a molecular genetic mechanism was identified. More than 100 mutations in nine genes, that encoding sarcomeric proteins have been identified in patients with HCM, which had led to the belief that HCM is a disease of contractile sarcomeric proteins of the cardiac muscle. Approximately two-thirds of all HCM cases are caused by the mutation of the myosin heavy chain (MyHC), cardiac troponin T (cTnT) and myosin binding protein-C (MyBP-C). Genotype-phenotype correlation studies suggest that mutations in the MyHC gene are associated with more extensive hypertrophy and a higher risk of SCD as compared to mutations in genes coding for other sarcomeric proteins, such as MyBP-C and cTnT. However, there is a noteworthy variability and factors, such as modifier genes and probably the environmental factors affect the phenotypic expression of HCM. The results of different functional studies suggest that in spite of the variety of the mutations, the initial defects in HCM is abnormal cardiac myocyte function. In this era of genetics and upcoming future of precision medicine, good knowledge of its molecular basis of any disease is crucial for patient management, and HCM is not different.
Faridpur Med. Coll. J. Jan 2019;14(1): 44-49
El conocimiento abierto ante las barreras de la evaluación institucional
Authors: García Ballesteros María Teresa
Published: March 2020

La necesidad de adoptar cambios en los parámetros evaluativos que utilizan las instituciones en el campo de la publicación científica, es una necesidad cada vez más apremiante para favorecer el uso de todas las posibilidades de difusión de la ciencia que los repositorios y redes sociales ofrecen.
Comparative Analysis of Automatic versus Fixed Positive Airway Pressure Therapy for Severe Obstructive Sleep Apnea
Authors: Cho Ilyoung , Kim Hwabin , Yi Kuen-Ik , Kim Sung-Dong , Mun Sue Jean , Cho Kyu-Sup
Published: March 2020

Background and Objectives The purposes of this study were to compare the purchase rate and adherence regarding the use of two machines, continuous positive airway pressure (CPAP) and automatic positive airway pressure (APAP), and to determine associated factors affecting the purchase rate and adherence of PAP in the treatment of severe obstructive sleep apnea (OSA).Subjects and Method From March 2016 to December 2017, 45 patients diagnosed with severe OSA by polysomnography were enrolled in this study. Patients were prescribed CPAP or APAP by one doctor and allowed to decide whether to purchase the machine after a one-month lease period, which was identified as the purchase rate. Adherence was identified as using the machine 4 h/night on 70% of nights following the PAP therapy of three months.Results The adherence rate of CPAP (84%) was statistically and significantly higher than APAP (55%) (p=0.033). However, there was no significant difference in the adherence rate between CPAP (76%) and APAP (63%). The mean pressure and 95th percentile leak were 8.62 cm H2O and 12.97 L/min in the CPAP and 10.55 cm H2O and 20.36 L/min in the APAP, respectively. The mean pressure and 95th percentile leak were significantly lower in CPAP than in APAP (p=0.010 and p=0.014, respectively).Conclusion Although adherence was not significantly different, the purchase rate was significantly higher in the fixed CPAP than in APAP, which may have been influenced by high pressure and leak patients experienced when using the particular PAP machine.
Marine macroinvertebrate species-area relationships, assemblage structure and their environmental drivers on submarine banks
Authors: Stortini CH , Petrie B , Frank KT , Leggett WC
Published: March 2020

Modern extensions of the theory of island biogeography (TIB) posit that the slope of the species-area relationship (SAR) reflects the insularity of ecological communities and is strongly influenced by species’ motility. We explore the relative insularity of crustacean, echinoderm and mollusk/Cirripedia assemblages in terms of both alpha diversity (species richness) and assemblage structure (relative biomass of species). These taxa/groups differ in adult motility and larval dispersal capacity. The habitats of interest were 10 offshore banks on the Scotian Shelf, northwest Atlantic Ocean, a region dominated by the NE- to SW-flowing Nova Scotia Current (NSC). Banks in the NE tended to be larger, more heterogeneous, cooler, less saline, more retentive and more productive (higher chlorophyll a) than those in the SW. Only mollusks/Cirripedia, the least motile and dispersive group, had a significant SAR slope, supporting TIB. For crustaceans and echinoderms, temperature/salinity properties and habitat heterogeneity, respectively, were important predictors of alpha diversity. Inter-bank variation in crustacean assemblage structure was accounted for largely by bank location relative to the NSC; the leading variables accounting for echinoderm and mollusk/Cirripedia assemblage structure were retention time and mean annual chlorophyll concentration, respectively. Along the NE to SW axis of the NSC, there was a substantial loss of species (7 crustacean, 9 echinoderm and 13 mollusk/Cirripedia species) and decreases in the biomass of common cold-water species. A complex interplay of species motility/dispersal capacity, local oceanography and habitat properties determine the extent to which (1) TIB applies to submarine macroinvertebrate assemblages and (2) upstream and downstream assemblages are interconnected.
Photon entanglement for life-science imaging: rethinking the limits of the possible
Authors: Zheltikov A M , Scully M O
Published: March 2020

Quantum entanglement is a powerful resource that revolutionizes information science, opens new horizons in communication technologies, and pushes the frontiers of sensing and imaging. Whether or not the methods of quantum entanglement can be extended to life-science imaging is far from clear. Live biological systems are eluding quantum-optical probes, proving, time and time again, too lossy, too noisy, too warm, and too wet to be meaningfully studied by quantum states of light. The central difficulty that puts the main roadblock on the path toward entanglement-enhanced nonlinear bioimaging is that the two-photon absorption (TPA) of entangled photons can exceed the TPA of uncorrelated photons only at the level of incident photon flux densities as low as one photon per entanglement area per entanglement time. This fundamental limitation has long been believed to rule out even a thinnest chance for a success of bioimaging with entangled photons. Here, we show that new approaches in nonlinear and quantum optics, combined with the latest achievements in biotechnologies, open the routes toward efficient photon-entanglement-based strategies in TPA microscopy that can help confront long-standing challenges in life-science imaging. Unleashing the full potential of this approach will require, however, high throughputs of virus-construct delivery, high expression efficiencies of genetically encodable fluorescent markers, high-brightness sources of entangled photons, as well as a thoughtful entanglement engineering in time, space, pulse, and polarization modes. We demonstrate that suitably tailored nonlinear optical fibers can deliver entangled photon pairs confined to entanglement volumes many orders of magnitude smaller than the entanglement volumes attainable through spontaneous parametric down-conversion. These ultracompact modes of entangled photons are shown to enable a radical enhancement of the TPA of entangled photons, opening new avenues for quantum entanglement in life-science imaging.
Cabinet Formation Elections: Among Opposition, Coalition, or Collegiality of The Party’s Chairperson
Authors: Sulardi Sulardi , Izziyana Wafda Vivid
Published: March 2020

Constitutional change is always tinged with a tense and lasting political constellation in both national and international contexts. the existence of transactional politics to gain seats constantly influences political dynamics in the election period. The method used in this research is the doctrinal method. Indonesia applies a presidential government system but does not fully follow the existing doctrine. several coalitions in the government coalition were made. As a result when the President and Vice President are nominated. political parties that support the nomination feel they have the right to join the government, as in the parliamentary system of government. The cabinet filling model is also influenced by supporting parties. It shows that political parties can collaborate to form a joint government, however, the President has the prerogative in determining who will be his minister. It should be carefully noted down that our country is a country adopting a presidential government system. As a result, the formation and the ministers elections of the government is not at the hand of the chairperson of the political parties coalition, but fully at the hand of the president as the President’s prerogative rights. This cannot be proceeded. Chairperson of the Political parties in a coalition may expect to get some seats of powers (minister) from the President

Keywords: cabinet; election; political; party; chairperson
Discretion of Morality (Pancasila Moral Relations in The Laws of Political Determination)
Authors: Zaelani Muhammad Azis , Handayani I Gusti Ayu Ketut Rachmi , Isharyanto Isharyanto
Published: March 2020

This study has purpose to determine the form of Pancasila moral relations as the legal ideology of Indonesia in guarding discretion amid political determination. In this study, the conceptual approach was used as a basis for thinking to guide answe tor the problem which then analyzed using qualitative approach. The results showed that Pancasila as the ideology of Indonesian law is able to guard discretion in the form of moral relations that are reflected in discretion users. The implication, it is necessary to optimize the interpretation of the Pancasila in Law Number 30 of 2014 concerning Government Administration to realize the ideals of justice in the bureaucracy as per the Pancasila insight. Therefore, Pancasila morals can guard the use of discretion in political determination.

Keywords: Pancasila; discretion; moral
“It’s Hard, but I’m Grateful for It”: A Patient Perspective on Hemodialysis
Authors: Allon Michael
Published: March 2020

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/K360/2020_03_26_KID0000712020.mp3
Elementi impresionizma u Moru Đure Sudete
Authors: Ivezić Talan Melanija , Slavić Dean
Published: March 2020

Članak tumači impresionističke elemente u pripovijetci „Mor“ Đure Sudete pozivajući se poglavito na postavke o impresionizmu Viktora Žmegača, teorije lirskoga Emila Staigera i percepcije zbilje Ernsta Macha. Autori proučavaju odnose ljudskoga tijela i prirode, probleme vremena i subjekta te iznose modernističke elemente nestabilnosti subjekta u obzoru glavnoga lika Mora, protagonistkinje Šu i njezina oca. Tekst također ukazuje na stilsku blizinu Sudetina Mora s drugim junacima iz modernističkoga razdoblja hrvatske književnosti, osobito Leskovarovih Marcela Bušinskoga i Đure Martića te Kozarčeva Đuke Begovića.
A Sustainability‑Based Multi‑Criteria Decision Approach for Information Systems Project Selection
Authors: Duan Sophia Xiaoxia
Published: March 2020

An effective approach for evaluating and selecting information systems (IS) projects in project management from a sustainability perspective is highly desirable in contemporary organisations with sustainable objectives. Such an approach, however, is absent from the literature. This paper presents a multi‑criteria analysis approach for effectively evaluating and selecting IS projects for project management in organisations based on their sustainability performance under environmental, economic, and social dimensions. Such an approach considers the subjective and uncertain nature of the IS project selection process using linguistic variables approximated by fuzzy numbers and effectively aggregates the subjective assessments for determining the overall sustainable performance of individual IS projects across all the selection criteria and their associated sub‑criteria. The proposed multi‑criteria decision‑making approach provides organisations with a proactive mechanism for effectively evaluating and selecting IS projects from a sustainability perspective. An IS project selection problem is presented to demonstrate the effectiveness of the approach.
Exploring the Factors Influencing e‑Government use: Empirical Evidence from Zimbabwe
Authors: Munyoka Willard
Published: March 2020

The proliferation of e‑government adoption in developing nations is anticipated to radically progress governance and transform government‑to‑citizen interactions and general administrative operations. More so, the benefits and level of e‑government adoption in the public sector have been echoed world over; but remains subdued in the context of developing nations. This study investigates the effect of effort expectancy, price value, service quality, optimism bias and behavioural intention on citizens’ decisions to use e‑government systems in Zimbabwe. Informed by the extended Unified Theory of Acceptance and Use of Technology (UTAUT2) as a theoretical lens, a research model for this study was adapted and tested using quantitative data collected from a survey of 489 respondents in Zimbabwe. Using confirmatory factor analysis and structural equation modelling, the proposed model was validated, thus, the major contribution of this research. Findings of this study may be of value in policy formulation and restructuring by practitioners on e‑government matters. Thus, the results shade a light to some of the key drivers and inhibitors of e‑government adoption in developing nations. Despite achieving its aim, this study has its limitations which constitute the future research direction
Review of the monograph by N.P. Bilenko, R.G. Ardashev «Medical and crime-forensic aspects for monthly biorhythms research (approaches for prediction and prevention of pathological aggressiveness and suicide)»
Authors: Editorial Article
Published: March 2020

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Maternal Mortality in Six East Anglian Parishes, 1539-1619
Authors: Allison Julia
Published: March 2020

This study examines the maternal mortality rate in six early modern rural parishes of East Anglia where a midwife was known to be practicing. Register entries from the six parishes are translated and transcribed and maternal outcomes established and discussed. Midwives and their families are researched to establish marital status, parity and social standing. Maternal mortality is calculated and differing rates for women experiencing multiple births, stillbirths and base births examined.
The Carnegie Dietary Survey of Interwar Britain
Authors: Shave Samantha A.
Published: March 2020

This research note describes an under-used collection of papers which document interwar income, nutrition and health in Britain which were created in the administration of the Carnegie Dietary Survey by John Boyd-Orr in the Rowett Institute with funding from the Carnegie United Kingdom Trust. The survey was conducted in 16 rural and urban places across England and Scotland between 1937–9, and are now held at the Specialist Collections Centre at the University of Aberdeen. While the importance of the survey in informing knowledge about nutrition and the development of rationing has been acknowledged in the field of social medicine, the survey data has primarily been used by epidemiological scientists and economic historians. After outlining the survey's past influences and uses, this item details the possible ways the data could be used by social, economic and local population historians.
Studying the Stayers: the Stable Population of Long Melford, Suffolk, over Two Hundred Years
Authors: Boothman Lyn
Published: March 2020

Studies of population movement are more common than those focusing on the long-term inhabitants of a settlement. This article, based on data from a population reconstruction, examines long-term and inter-generational stability amongst couples resident in Long Melford, Suffolk, both those with local family links and those who migrated from elsewhere. The study focuses on three periods: 1661–91, 1753–83 and 1831–61 and finds that the proportion of couples who met the stability indicators increased over time; overall the proportion of wives who met the criteria increased more than that of husbands. A comparison of the children of these couples is used to relate stability amongst the couples and their children and to highlight issues relating to assessing the stability of single adults.
The Experience of Plague in East Kent, 1636-38
Authors: Bolton Margaret
Published: March 2020

On 2 July 1637 43-year-old Elizabeth Burgess, from Canterbury, was buried at Birchington, Kent, having died of the plague in the hamlet of Wood in that parish. She was the first victim of an outbreak of plague in 1637. This article firstly examines that outbreak in Birchington in detail; then it considers how far the parish's experience matched that in nearby Faversham and Sandwich. It finally discusses the extent to which the infection spread to the surrounding area.
Obstructive Sleep Apnea (OSA) Sebagai Faktor Resiko Hipertensi
Authors: Azzahra Sharlene Sabrina
Published: March 2020

Obstructive Sleep Apnea (OSA) atau Apnea Tidur Obstruktif merupakan kondisi umum yang ditandai dengan obstruksi saluran nafas bagian atas yang berulang. OSA juga ditandai dengan rasa kantuk di pagi hari, sering bangun saat tidur, mendengkur, penurunan konsentrasi dan gangguan ingatan. Obstruksi saluran nafas bagian atas tersebut dapat berbentuk parsial(hypopnea) atau komplit(apnea). Kondisi ini dapat terjadi karena beberapa faktor, seperti faktor keturunan, faktor kongenital seperti abnormalitas pada struktur anatomi dan faktor umur, jenis kelamin dan berat badan maupun kondisi medis lainnya. OSA berkontribusi dalam berkembangnya penyakit-penyakit kardiovaskular, seperti hipertensi. Hipertensi adalah gangguan pada pembuluh darah yang didefinisikan apabila tekanan darah sistolik ≥140 mmHg dan / atau tekanan darah diastolik ≥90 mmHg. Secara umum, hipertensi akibat OSA dimulai dari keadaan hipoksemia yang dilanjutkan oleh inflamasi sistemik dan stress oksidatif, disfungsi endotel, aktivitas saraf simpatik dan aktivasi sistem renin-angiotensin-aldosteron, dan kurang tidur yang menghasilkan kontriksi pembuluh darah perifer, peningkatan denyut jantung, dan kekakuan pada pembuluh darah arteri.
Tokoh Pendidikan Islam Perempuan Rahmah El-Yunusiah
Authors: Furoidah Asni
Published: March 2020

One way to improve the lot and raise the dignity of women is through education. The first female Islamic education figure in Indonesia was Rahmah el-Yunusiyah, she was a figure of women's struggle during the physical revolution. He was born from a family with a strong religious education background. During childhood Rahmah el-Yunusiyah started school at the Diniyah School led by her brother, Zainuddin Labay, which was founded in 1915 for sons and daughters using modern learning systems and lessons.

            The role of Islamic education as one of the right ways to raise the degree of women has had since he was a teenager. Rahmah's belief in the role of education was realized with the establishment of the school under the name AL-Madrasah AL-Diniyyah Li Al-Banat in 1923 to attract the attention of the community especially mothers, intellectuals and groups who were very strong in holding old traditions, this newly founded school was also called Diniyyah School Poetri. Trinity education system, which is close cooperation between the school environment, dormitories, and households or the community.
Metode Qira Ah Muwahhadah dalam Membentuk Keserasian Bacaan Al Qur An (Studi Kasus di Pondok Pesantren Madrasatul Qur An (Mq) Tebuireng Jombang)
Authors: Sya’roni Hasan Moch.
Published: March 2020

The implementation of the Qira ah Muwaḥḥadah Method is expected to be able to form the reading of Al Qur an santri Madrasatul Qur an Tebuireng which were originally influenced by dialects from each region to be harmonious in accordance with the Qira ah standard taught by K.H.M. Yusuf Masyhar. Based on the background above, this thesis is focused on three aspects of description, namely: 1) learning planning of Qira ah Muwaḥḥadah in Islamic Boarding School Madrasatul Qur an Tebuireng 2) the learning process of Qira ah Muwaḥḥadah in Islamic Boarding School Madrasatul Qur an Tebuireng 3) evaluation of learning Qira ah Muwaḥḥadah at the Islamic Boarding School Madrasatul Qur an Tebuireng. This study states that the implementation of the Qira ah Muwaḥḥadah method includes: classical fas} ah} ah development, Al Qur'an payment, and Al Qur'an memorization. Evaluation of the learning of the Qur'an Qira ah Muwaḥḥadah carried out as a whole, both evaluations that are formal (the Qur'anic test) which is carried out every 6 months and evaluations relating to the learning process of the Qur'an Qira ah Muwaḥḥadah every month. The results of the Qira ah Muwaḥḥadah method at the Madrasatul Qur an Tebuireng Islamic Boarding School can form the Qur'anic readings of the students who were originally influenced by their respective regional dialects to be harmonious according to the Qira ah standard taught by K.H. M. Yusuf Masyhar, so that students of the Islamic Boarding School in Madrasatul Qur an Tebuireng can practice the reading of the Qur'an in their respective regions. Criteria for harmony in reading the Qur'an include: harmonious in the field of proficiency in saying makharijul h} uruf, harmonious in the practice of tajwid when reading the Qur'an and be harmonious in rhythm or song when chanting the verses of the Qur'an.