bluuebunny/crossref_metadata_2025 huggingface dataset:
Bovine Ephemeral Fever (BEF) : Penyebab, Epidemiologi, Diagnosa, dan Terapi
Authors: Nururrozi Alfarisa , Indarjulianto Soedarmanto , Yanuartono Yanuartono , Purnamaningsih Hary , Raharjo Slamet
Published: January 2021

Bovine ephemeral fever (atau 3-day sickness) adalah penyakit demam akut pada sapi dan kerbau yang disebabkan oleh Ephemerovirus dari keluarga rhabdoviridae dan ditularkan oleh vektor arthropoda. Penyakit tersebut biasa terjadi di daerah tropis dan subtropis. Dalam banyak kasus, dampak utamanya adalah pada penurunan produktivitas, produksi susu, kondisi tubuh, gangguan reproduksi, dan periode pemulihan yang lama pada beberapa hewan. Gejala klinis bervariasi pada setiap individu hewan, tetapi pada umumnya diawali dengan demam yang bersifat bifasik melanjut menjadi polifasik. Mortalitas biasanya rendah, namun, peningkatan kasus berakibat fatal telah dilaporkan dalam beberapa wabah akhir-akhir ini. Penyakit ini tersebar luas diberbagai daerah di Indonesia. Secara umum tidak menimbulkan kerugian ekonomi yang besar, asalkan segera mendapatkan pertolongan medis yang memadai sehingga tidak terjadi komplikasi dengan penyakit lain. Tulisan ini bertujuan untuk mengulas penyebab, metode diagnosa, dan terapi yang dapat dilakukan untuk menanggulangi kejadian BEF.
Aktivitas Antimikroorganisme Ekstrak Etanol 70 % Biji Bengkuang Terhadap Staphylococcus epidermidis, Pseudomonas aeruginosa dan Candida Albican
Authors: Rahminiwati Min
Published: January 2021

Selain sebagai biopestisida ekstrak etanol 70 % biji bengkuang dilaporkan mempunyai aktivitas antibakteri terhadap bakteri gram positif Staphylococcus aureus dan bakteri gram negatif Escherichia coli dan Candida alibican. namun efeknya terhadap Staphylococcus epidermidis dan Pseudomonas aeruginosa, belum dketahui. Penelitian ini ditujukan untuk menentukan aktivitas antimikroorganisme ekstrak etanol 70 % biji bengkuang lokal  terhadap  Staphylococcus epidermidis, Pseudomonas aeruginosa dan  Candida Albican menggunakan teknik difusi agar dan metoda dilusi.  Aktivitas antimikroorganisme ekstrak diteliti pada konsentrasi 10% 12% 14%, 16% dan sebagai kontrol negatif, kontrol positif antibakteri dan kontrol positif antifungal masing masing digunakan akuadestilata.  ertromisin 10 ppm, ketokonazol 10 ppm. Data yang diperoleh menunjukkan bahwa ekstrak efektif sebagai antibakteri terhadap Staphylococcus epidermidis dan Pseudomonas aeruginosa serta sebagai antifungi terhadap Candida albican, pada konsentrasi bunuh minimum 10 mg/ml. Kata kunci: Ketokonazol, Eritromisin Pseudomonas biji bengkuang Candida albikan
Virulence Characteristic of Avian Pathogenic Escherichia coli (APEC) Isolates
Authors: Adrenalin Sruti Listra , Imanjati Lynda Nugrahaning , Fauziah Ima , Prakasita Vinsa Cantya , Widyarini Sitarina , Wahyuni Agnesia Endang Trihastuti
Published: January 2021

Avian pathogenic Escherichia coli (APEC) is a cause of colibacillosis in poultry, one of the respiratory disease that causes serious problems in the poultry industry. The APEC can cause high mortality and culling, decreased production, and high costs of treatment. Manifestations of colibacillosis are airsacculitis, perihepatitis, and pericarditis. The APEC serotypes that are widely identified in the field are O1K1, O2K1, and O78K80. Embryo lethality assay (ELA) is a method for determine the virulence of APEC serotypes. The aim of this study was to determine the virulence characteristic of APEC isolates. Five APEC serotypes O1K1, O2K1, O78K80, O157H7, and unknown serotype were used for ELA method by inoculated E. coli into chorioallantoic of specific pathogen free 12-days old embryos. Each group of 10 embryos, inoculated E. coli dose of 100-500 CFU/ 0,1 ml. Candling was carried out for 6 days (18-days old embryo) to determined the mortality and pathological lesions. The percentage of embryo mortality post-inoculated with APEC O1K1, O2K1, unknown serotypes were 100% (10/10), O78K80 serotype was 90% (9/10), and O157H7 serotype was 70% (70%). Lesions of all embryos were cranial and extremity hemorrhage. In this study, E. coli isolates had high virulence.
Septicemic Infection Suspect In Jenkins' Whipray Pateobatis jenkinsii (Annandale, 1909): A Case Report
Authors: Rizkiantino Rifky , Binol Ridzki M.F.
Published: January 2021

A wild-captive male Jenkins' whipray was found dead in a quarantine tank with a clinical sign before death in the form of decreased appetite for a week. The treatment history was oral administration of enrofloxacin antibiotic tablets. The therapy period lasts for ten days. The last treatment was the administration of Hepavit® (liver extract) and intramuscular injection of enrofloxacin antibiotic. One day before the death, blood was collected and then examined for the hematocrit and some parameters of chemical blood. The results of blood examination were found a decrease in blood urea nitrogen (BUN), alkaline phosphatase (ALP), and alanine aminotransferase (ALT) levels, increased glucose level, decreased total protein and albumin levels, and increased globulin level. Anatomical pathology examination was found lesions on the tail, around the eyes, and claspers. Hemorrhagic lesions were found in the mucous layer of the esophagus, stomach, and spiral colon. The blood clot was found under the tunica layer of testicular organs. The liver is damaged by showing a non-homogeneous coloration, organ thickening, congestion, and fragile consistency. Based on the results of the blood examination and was supported by the results of the anatomical pathology examination after death, it is suspected that the fish died due to the condition of septicemia infection during the previous few weeks.
Swab Bukal Sebagai Bahan Sexing Piyikan Burung Kenari (Serinus canaria) dan Burung Merpati (Columba livia)
Authors: Akrom Afif Muhammad , Indarjulianto Soedarmanto , Yanuartono Yanuartono , Susmiati Trini , Nururrozi Alfarisa , Raharjo Slamet , Permana Rief Ghulam Satria , Sitompul Yeremia Yobelanno
Published: January 2021

Teknik sexing pada burung secara molekuler dengan metode PCR telah banyak dikembangkan, tetapi sampel yang digunakan adalah darah dan bulu yang dianggap invasif. Penelitian ini bertujuan untuk mempelajari efisiensi sampel swab bukal sebagai sumber DNA dalam sexing dengan metode PCR. Penelitian ini menggunakan 10 ekor burung kenari (Serinus canaria) yang terdiri dari 6 ekor burung dewasa (3 jantan dan 3 betina) dan 4 ekor kenari piyikan (umur 14 – 18 hari) yang belum diketahui jenis kelaminnya serta 6 ekor merpati (Columba livia) dewasa (3 jantan dan 3 betina) dan 7 ekor merpati piyikan (umur 14 – 25 hari) yang belum diketahui jenis kelaminnya. Amplifikasi fragmen gen dilakukan menggunakan metode PCR dengan pasangan primer CHD1F/CHD1R.Hasil visualisasi produk PCR menunjukkan semua burung jantan dewasa menghasilkan satu band (± 500 bp), sedangkan burung betina dewasa menghasilkan dua band (± 500 bp dan ± 300 bp). Amplifikasi gen dari swab bukal burung kenari muda didapatkan 2 ekor jantan dan 2 ekor betina, sedangkan dari swab bukal burung merpati muda didapatkan 6 ekor jantan dan 1 ekor betina. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa sampel swab bukal terbukti efisien sebagai sumber DNA dalam sexing burung khususnya burung piyikan.
Gonadotropine Releasing Hormone (GnRH) Receptor Profile from Cow’s Hypothalamus
Authors: Nurani Irma Dian
Published: January 2021

Gonadotropine Releasing Hormone (GnRH) is one of the recommended hormones to overcome ovulation problems and it can increase pregnancy rate so that it is used in government programs to increase cattle population in Indonesia, although the results are not yet optimal. The purpose of this study is to compare the composition of bovine GnRH receptor nucleotides with the GenBank reference so that the level of genetic diversity of bovine receptors in Indonesia is known. PCR product sequencing using Promoter F and Exon 1 R primers were further aligned with the reference sequences of Bos Taurus GnRHR mRNA GenBank using the MEGA X program. The results of the analysis found the presence of Single Nucleotide Polymorphism (SNP) in the coding region  of 1st cow  position 38(A> T), 261(C > T), 342(C >T), 411(C >T) and 495(C > T) and 2nd cow positions 261(C >T). Changes in amino acids were also detected in 1st cow position 13 (H> L). The presence of SNP was found to indicate genomic variation between individuals at cattle receptors in Indonesia.
Пары микровесовых торов в $GL_n$
Authors: Нестеров Владимир Викторович , Вавилов Николай Александрович
Published: January 2021

В настоящей заметке мы доказываем теорему редукции для подгрупп полной линейной группы ${\operatorname{GL}}(n,T)$ над телом $T$, порожденных парой микровесовых торов одного и того же типа. Оказывается, что любая пара торов вычета $m$ сопряжена такой же паре в ${\operatorname{GL}}(3m,T)$. При этом пары, которые не могут быть вложены далее в ${\operatorname{GL}}(3m-1,T)$, образуют единственную ${\operatorname{GL}}(3m,T)$-орбиту.В случае $m=1$ нам остаётся проанализировать ${\operatorname{GL}}(2,T)$, что было сделано два десятилетия назад вторым автором, Коэном, Кюйперсом и Стерком. Для следующего значения $m=2$ это означает, что единственными случаями, которые должны быть рассмотрены, являются группы${\operatorname{GL}}(4,T)$ и ${\operatorname{GL}}(5,T)$. В этих случаях задача может быть полностью решена (прямыми, но достаточно длинными) матричными вычислениями, которые осуществлены в готовящейся статье авторов.
Борис Максимович Бредихин и его научно-педагогическая деятельность
Authors: Добровольский Николай Михайлович , Пачев Урусби Мухамедович , Чубариков Владимир Николаевич
Published: January 2021

Статья посвящена жизни и научно-педагогической деятельности известного математика, доктора физико-математических наук Бориса Максимовича Бредихина (1920–1994) в связи со 100-летием со дня его рождения. В ней сначала приводятся биографические сведения из его жизни. Основная часть нашей работы посвящена достижениям Б. М. Бредихина в теории чисел. Даётся анализ его научных публикаций.
О слабой теореме универсальности
Authors: Вячеславовна Кирилина Анастасия
Published: January 2021

Данная работа посвящена вопросам приближения квадратичной алгебраической решётки целочисленной решёткой. В ней вычисляются расстояния между квадратичной алгебраической решёткой и целочисленной решёткой, когда они заданы числителем и знаменателем подходящей дроби к корню квадратному из дискриминанта d — свободного от квадратов натурального числа.Результаты данной работы позволяют изучать вопросы о наилучших приближенияхквадратичных алгебраических решёток целочисленными решётками.
Новые границы алгебраической константы Никольского
Authors: Горбачев Дмитрий Викторович , Мартьянов Иван Анатольевич
Published: January 2021

Пусть $M_{n}=\sup_{P\in \mathcal{P}_{n}\setminus \{0\}} \frac{\max_{x\in

[-1,1]}|P(x)|}{\int_{-1}^{1}|P(x)|\,dx}$ --- константа Никольского между

равномерной и интегральной нормами для алгебраических полиномов с комплексными

коэффициентами степени не выше $n$. D. Amir и Z. Ziegler (1976) доказали, что

$0.125(n+1)^{2}\le M_{n}\le 0.5(n+1)^{2}$ для $n\ge 0$. Аналогичная оценка

сверху получена T.K. Ho (1976). F. Dai, D. Gorbachev и S. Tikhonov (2019--2020)

уточнили этот результат, установив, что $M_{n}=Mn^{2}+o(n^{2})$ при $n\to

\infty$, где $M\in (0.141,0.192)$ --- точная константа Никольского для целых

функций экспоненциального сферического типа в пространстве

$L^{1}(\mathbb{R}^{2})$ и функций экспоненциального типа в $L^{1}(\mathbb{R})$

с весом $|x|$.

 

Мы доказываем, что для произвольного $n\ge 0$ имеем $M(n+1)^{2}\le M_{n}\le

M(n+2)^{2}$, где $M\in (0.1410,0.1411)$. Данное утверждение также позволяет

уточнить точную константу Джексона--Никольского для полиномов на евклидовой

сфере $\mathbb{S}^{2}$. Доказательство базируется на взаимосвязи алгебраических

констант Никольского с тригонометрическими константами Бернштейна--Никольского

и наших результатах об оценках последних (2018--2019). Также мы применяем

характеризацию экстремального алгебраического полинома, полученную D. Amir и

Z. Ziegler (1976), В.В. Арестовым и М.В. Дейкаловой (2015). С помощью этой

характеризации мы составляем тригонометрическую систему для определения нулей

экстремального полинома, которую решаем приближенно с необходимой точностью с

помощью метода Ньютона.
INFLUÊNCIA DO TEOR DE CIMENTO NA RESISTÊNCIA À COMPRESSÃO SIMPLES DE UM SOLO RESIDUAL CIMENTADO ARTIFICIALMENTE
Authors: Somensi Thaise Canton , Togni Guilherme , Armani Augusto , Leon Helena Batista , Mattos João Rodrigo Guerreiro , Gauer Emanuele Amanda
Published: January 2021

O solo é um material essencial para qualquer obra de engenharia, entretanto, o mesmo pode não apresentar os parâmetros solicitados em projeto. Em vista disso, inúmeros são os métodos para contornar esse problema, entre eles, a estabilização de solos. O presente artigo tem por finalidade avaliar e comparar o comportamento mecânico de uma mistura de um solo residual estabilizado com cimento. As amostras foram moldadas no sistema de triplicatas, com 50 mm de diâmetro e 100 mm de altura. Para as misturas, foram empregados duas massas específicas aparente secas (ρd) nos valores de 1,25 e 1,35 g/cm³ e quatro diferentes teores de cimento, sendo eles 5%, 7%, 9% e 11%. A fim de realizar uma comparação, também foram moldados corpos de prova sem a adição de cimento. Após moldagem, todas as amostras permaneceram em cura durante 7 dias em câmara úmida, a uma temperatura de 23°C ± 2°C, com umidade relativa do ar superior a 95%. A fim de minimizar os efeitos de sucção, os corpos de prova foram colocados em imersão 24 horas antes de ser realizada a ruptura. A resistência das amostras foi obtida através do ensaio de resistência à compressão simples. Verifica-se que a resistência mecânica dos corpos de prova cresce com o aumento do teor de cimento adicionado nas misturas e da massa específica aparente seca de moldagem. Dessa forma, conclui-se que tanto a compactação como a adição do cimento CPV-ARI apresentaram um grande potencial para a estabilização do referido solo.
ESTUDO DE PROPOSTAS PARA UM SISTEMA DE TRAÇÃO 4X4 EM UM VEÍCULO DO TIPO BAJA SAE
Authors: Zotti Eduardo , Hattge Lenz Misael David , De Souza Ricson Rocha
Published: January 2021

O presente artigo refere-se a um estudo de propostas para um sistema de tração 4x4 em um veículo off-road de competição do tipo BAJA SAE. Assim, propõe-se uma análise comparativa com base em alguns critérios pré-estabelecidos e em alguns modelos existentes no mercado de sistemas de tração AWD (all-wheel drive) e 4WD (4-wheel drive). Nas aplicações automotivas, em especial do tipo off-road, sistemas de tração integral, que permitam a aplicação de energia e controle em todas as rodas do veículo, são de relevante importância para a experiência e segurança de utilização do piloto, através da maior estabilidade proporcionada e consequente capacidade de transposição de obstáculos. Diante deste contexto, neste trabalho, foram analisadas quatro propostas distintas para a construção de um sistema de tração integral (AWD e 4WD), para um veículo Baja SAE (Society of Automotive Engineers), levando em conta aspectos relacionados às características funcionais e custos de fabricação, bem como facilidade de implementação e manutenção em situações de campo. É importante frisar que o estudo não envolve o dimensionamento do sistema, mas sim uma seleção prévia de componentes para levantamento de alterações necessárias no veículo para a implantação de um sistema de tração 4x4. Os projetos das propostas foram realizados em software SolidWorks e, como resultado das condições de seleção através de uma matriz de decisão, foi escolhida a proposta de um diferencial dianteiro, com modificação na caixa de redução, alcançando a pontuação pela matriz de decisão de 8,2 pontos, sendo essa a adequação com maior potencial de implantação em um veículo BAJA SAE.
BLUEPATH: SISTEMA DE LOCALIZAÇÃO INDOOR
Authors: Mittelstadt Raul Silvério , Pretto Fabrício
Published: January 2021

Localizar-se atualmente tornou-se um desafio a ser enfrentado. Com o desenvolvimento das cidades, a quantidade de rotas e lugares aumentou consideravelmente. Para suprir essa necessidade de chegar em lugares desconhecidos ou a melhor rota a seguir, surgiu o GPS que se tornou popular rapidamente, devido à sua grande efetividade e quantidade de ferramentas. No entanto, o GPS tem suas limitações no que diz respeito à precisão, o que inviabiliza sua utilização em ambientes internos. Neste sentido este trabalho apresenta o desenvolvimento de um aplicativo de localização indoor, para facilitar o processo de localização em ambientes fechados. Para atingir tal objetivo, foram distribuídos transmissores Bluetooth em um ambiente interno para que o aplicativo consiga, por meio dos transmissores, determinar a localização. Para determinar a localização, foram utilizadas técnicas de orientação como: RSSI (Received Signal Strength Indicator) e ToA (Time of Arrival). Um estudo detalhado das tecnologias e técnicas envolvidas, contemplam o escopo deste trabalho. Com os resultados obtidos foi possível determinar a localização do smartphone em um ambiente interno.
The Role of Video-Assisted E-Learning in Intrauterine Contraceptive Device Insertion Training
Authors: Peng Ng Lai , Ling Eileen Koh Yi
Published: January 2021

Introduction: Intrauterine contraceptive device (IUCD) insertion is an important procedural skill for primary care physicians. Procedural skill training can be challenging. E-learning has been rapidly employed in medical education. The purpose of this study was to evaluate the role of a video-assisted e-learning module in knowledge and skill transfer for IUCD insertion training.
Methods: We used a quasi-experimental, one-group, pre/posttest study design. Thirty-one primary care doctors (family medicine residents and new medial officers) at a primary care training center participated in the study. All participants assessed the e-learning module at the training center. We performed on-site pre/posttests of knowledge and procedural steps (posttest only). We obtained satisfaction with e-learning and perceived confidence level with an anonymous questionnaire survey.
Results: There was a significant increase in the knowledge test scores from a median interquartile range score of 12 (10-15) to 18 (17-19) post-e-learning (P<.01). All participants attained the minimum passing score of 15 of 20 (75%) post-e-learning. However, only 20 of 31 (64.5%) participants met the minimum passing standard for procedural step test post-e-learning. Ninety-three percent of the participants reported satisfaction with the e-learning course. The median score for confidence level in performing the procedure increased significantly after e-learning.
Conclusion: The e-learning module may be an effective way of delivering instructional content in procedural training. It provides time and location flexibility and is useful for pretraining. Psychomotor skills for clinical procedures, however, may be difficult to acquire by e-learning alone. It must be supplemented with deliberate practice and hands-on learning in simulation workshops.
Proteome-wide identification of S-sulfenylated cysteines in Brassica napus
Authors: Iqbal Sidra , Yu Liangqian , Zhang Yuting , Zhang Guofang , Ali Usman , Lu Shaoping , Yao Xuan , Guo Liang
Published: January 2021

Deregulation of reduction-oxidation (redox) metabolism under
environmental stresses results in enhanced production of intracellular
reactive oxygen species (ROS), which ultimately leads to
posttranslational modifications (PTMs) in structure and molecular
function of responsive proteins. Redox PTMs are important mediators of
cellular signalling and regulation and several proteomic approaches
attempted to quantify them under various stresses in plants. We aimed to
generate large-scale redox proteomics data in response to short-term
salt stress in Brassica napus by analyzing reversible cysteine
modification. We employed iodoTMT approach to analyze the redox proteome
of Brassica napus seedlings under control and salt stress conditions. We
identified 2,010 peptides in 1,017 proteins, of which 1,821 sites in 912
proteins had oxidative modification. The redox homeostasis of biology
processes in chloroplast and cytoplasm were mainly affected and the
modification levels of proteins involved in photosynthesis and
glycolysis pathways were significantly changed. Two oxidatively modified
proteins were selected from the candidates and their in vitro activity
under oxidative stress was assayed and validated the findings of this
proteomics study. This targeted approach should contribute to the
understanding of redox-based molecular changes prevailing in Brassica
napus proteome subjected to salt stress and the mechanism adopted to
cope with it.
The cost of evolved constitutive lac gene expression is usually, but not always, maintained during evolution of generalist populations
Authors: Phillips Kelly , Cooper Tim
Published: January 2021

Beneficial mutations can become costly following an environmental
change. Compensatory mutations can relieve these costs, while not
affecting the selected function, so that the benefits are retained if
the environment shifts back to be similar to the one in which the
beneficial mutation was originally selected. Compensatory mutations have
been extensively studied in the context of antibiotic resistance,
responses to specific genetic perturbations and in the determination of
interacting gene network components. Few studies have focused on the
role of compensatory mutations during more general adaptation,
especially as the result of selection in fluctuating environments where
adaptations to different environment components may often involve
tradeoffs. We examine if costs of a mutation in lacI, which deregulated
expression of the lac operon in evolving populations of Escherichia coli
bacteria, was compensated. This mutation occurred in multiple replicate
populations selected in environments that fluctuated between growth on
lactose, where the mutation was beneficial, and on glucose, where it was
deleterious. We found that compensation for the cost of the lacI
mutation was rare, but, when it did occur, it did not negatively affect
the selected benefit. Compensation was not more likely to occur in a
particular evolution environment. Compensation has the potential to
remove pleiotropic costs of adaptation, but its rarity indicates that
the circumstances to bring about the phenomenon may be peculiar to each
individual or impeded by other selected mutations.
Rare Cases of Medulloblastoma with Hypermutation
Authors: Bagchi Aditi , Beddows Ian , Cornelius Albert , Robinson Giles , Jewell Scott
Published: January 2021

Medulloblastoma (MB) is the most common malignant brain tumor of
childhood and is reported to have a low mutational burden. However, in
this study, we identified nine MBs with high mutational burden by next
generation sequencing. Of them, two had canonical mutations in the POLE
proof-reading domain, where a large proportion of mutations in these
tumor genomes contributed to signature 10. We report very rare
incidences of hypermutation in MB and mechanisms driving mutagenesis.
Strikingly, of the four known molecular subgroups in MB—-SHH, WNT,
Group 3, and Group 4—both the POLE-mutated MBs belonged to the SHH
subgroup.
Nuovi processi biologici a membrane per la depurazione sostenibile delle acque reflue
Authors: Cairone Stefano
Published: January 2021

I bioreattori a membrana (MBR) combinano il processo di degradazione
biologica a fanghi attivi e il processo fisico di filtrazione con
membrane, costituendo un sistema di trattamento avanzato delle acque
reflue. Tra i numerosi vantaggi  di questa tecnologia, assume
particolare importanza l’elevata efficienza depurativa: gli MBR
garantiscono la rimozione sia di contaminanti convenzionali che di
contaminanti emergenti. Tuttavia, gli MBR presentano degli svantaggi
legati principalmente agli elevati costi di investimento e di gestione
degli impianti e al controllo del fouling. L’introduzione dei
bioreattori a membrana dinamica auto-formante (SFDMBR), basati
sull’utilizzo di un materiale di supporto a pori grossolani a basso
costo per la formazione di una membrana dinamica auto-formante, consente
di ottenere elevate prestazioni depurative a fronte di ridotti costi di
investimento. Gli elettro-bioreattori a membrana (e-MBR) combinano
processi elettrochimici nei sistemi MBR, con conseguente incremento
dell’efficienza depurativa e riduzione del fouling. Combinando la
tecnologia SFDMBR con quella e-MBR si ottiene un sistema ibrido
estremamente innovativo: l’elettro-bioreattore a membrana dinamica
auto-formante (e-SFDMBR).
Aortic Stenosis in bicuspid and tricuspid aortic valves are two different scenarios
Authors: Carrero Maria Celeste , Masson Gerardo , Constantin Ivan , Ruano Martin , Mezzadra Maria , Pessio Carla , Rosetti Matias Lopez , Babio Gonzalo Diaz , Veron Facundo , Diaz Sandra , Stampone Gustavo , Stutzbach Pablo
Published: January 2021

Patients with bicuspid aortic valve (BAV) represent a significant
proportion of adults with severe aortic stenosis (AS) requiring aortic
valve intervention (AVI). Evidence is discordant concerning progression
of AS in BAV. The aim of this study was to compare baseline
characteristics and the impact of the aortic valve phenotype on major
cardiovascular outcomes. Methods: Retrospective observational study
(consecutive AS in database, 2014-2016, third-level institution).
Baseline characteristics were compared between BAV (n = 43) and
tricuspid (TAV) (n = 159) patients. Primary end point was a composite of
mortality and AVI. Survival analysis and logistic regression analysis
was used to identify predictors of primary end-point. Results: 202
patients (72.2 ± 13.4 years, 63% men) were included. Patients with TAV
were older, had more comorbidities and less aorta dilation. No
significant differences were observed in the primary end point between
the two valve phenotypes (34.8 vs. 40.8%; p=0.47, follow-up of 3.2 ±
1.6 years). In BAV group most of the events were at the expense of AVI
(32.5 vs. 13.8%; p=0.001). The incidence of CV death was similar
between both groups (4.8% vs. 12%, p=0.25). Non-CV mortality was
higher in TAV group (16.8% vs 0%, p=0.001). Vmax and dimensionless
index were independently associated with primary end point
(p<0.001). Conclusions: Patients with AS have a high incidence
of all-cause mortality and aortic valve intervention, regardless of
valve phenotype. In particular, patients with BAV present different
clinical characteristics with lower overall mortality and a more
advanced AS when requiring aortic valve intervention.
Dezinformacije u digitalnom dobu
Authors: Popovac Josip
Published: January 2021

U radu se raspravlja o „suvremenosti“ fenomena dezinformacija kroz prizmu povijesnog razvoja medija uzimajući u obzir političko-ekonomske aspekte pojedine faze, samu prirodu istine i dezinformacije kao manipulativni alat te eskalaciju dezinformacija u korpusu javnog znanja s posebnom pažnjom na ulogu društvenih mreža. Društvene mreže dokidaju komunikacijski monopol koji je do sada bio rezerviran za elitne krugove, čime masovno komuniciranje postaje globalno dostupno svakom vještom pojedincu. Rad se bavi i modelom suprotstavljanja utjecaju dezinformacija prema načelima europskog pristupa suprotstavljanja dezinformacijama, naglašavajući borbu za istinu kao prikladniji
model od borbe protiv laži.
The conference “A step into science” 2020 by the Petnica Science Center
Authors: Bozic Nikola
Published: January 2021

The Petnica Science Center (PSC) organized the regular Conference ?A Step
into Science?, BOOK AND EVENT REVIEW December 7-12, 2020
online. PSC is an independent, nonprofit organisation for
extracurricular, formal, and informal, science education. For the past 38
years, it has been a place of free thinking and innovative ideas for
students with strong interests in science and the scientific method. PSC
utilizes a peer-to-peer education system, where university students are the
tutors of high school students, providing a more informal learning setting
to foster the development of scientific ideas. Peer to peer education, as an
important aspect of the PSC model is highly beneficial for both young tutors
(university students) and their slightly younger students. The primary
philosophy is to promote scientific literacy and help high school students
to understand the scientific method. By using hands-on approaches to
research and science, students are taught how to read appropriate
literature, trained in basic research methods, and encouraged to develop
their own scientific questions. As students progress through the program,
they engage in training and activities that enable them to create their own
independent research project proposals. After the project proposal is
reviewed and approved, the students have the opportunity to conduct their
own research, analyze the results, and write a final peer-reviewed
manuscript. The selected manuscripts are traditionally presented at the
Petnica annual conference as poster and oral presentations, this time
carried out online with great success. More than 100 participants joined the
daily presentations and joined in lively discussions on the presented works.
The manuscripts are also published in annual proceedings by PSC.
Improving Microvascular Complications Screening Rates: Implementation of a Dedicated Diabetes Clinic (Diabetes 360) in an Underserved Area in Philadelphia, PA
Authors: Sombra Lorenna Rodrigues Silva , Hares Horacio David , Behme Matthew , Curet Karla M.
Published: January 2021

Quality Improvement Success Stories are published by the American Diabetes Association in collaboration with the American College of Physicians and the National Diabetes Education Program. This series is intended to highlight best practices and strategies from programs and clinics that have successfully improved the quality of care for people with diabetes or related conditions. Each article in the series is reviewed and follows a standard format developed by the editors of Clinical Diabetes. The following article describes the establishment of a dedicated patient-centered diabetes clinic within an academic primary care center serving a diverse population in Philadelphia, PA.
Improvement of Statin Utilization in Veterans With Diabetes Through Pharmacy Interventions
Authors: Kim Sang Wan , Chen Jennifer , Wegener Kevin J. , Resch Nina D. , Neff Kimberly M. , Nawarskas Ann D.
Published: January 2021

This series is intended to highlight best
practices and strategies from programs and clinics that have successfully
improved the quality of care for people with diabetes or related conditions.
Each article in the series is reviewed and follows a standard format developed
by the editors of Clinical
Diabetes. The following article describes an effort aimed at
increasing the use of statins among veterans with diabetes at a Veterans
Affairs medical center in New Mexico.
OPTIMALISASI PERAN PEMBIMBING KEMASYARAKATAN DALAM PENCEGAHAN RESIKO RESIDIVIS TERHADAP KLIEN PEMASYARAKATAN (STUDI KASUS DI BALAI PEMASYARAKATAN KELAS II PEKANBARU)
Authors: Ramadhan Risky Rohmat
Published: January 2021

Peran Pembimbing Kemasyarakatan dalam upaya pencegahan resiko residivis masih belum berjalan secara optimal. hal ini dikarenakan masih adanya beberapa hambatan yang dialami oleh petugas Pembimbing Kemasyarakatan baik itu dari segi pemberian program bimbingan maupun pengawasan yang dilakukan terhadap klien. Penelitian ini bertujuan untuk memberikan penjelasan tentang tugas Pembimbing Kemasyarakatan beserta faktor-faktor yang menjadi penyebab terjadinya pengulangan tindak pidana atau residivis yang dilakukan oleh klien Pemasyarakatan. dari hasil pembahasannya masih perlu adanya penguatan terhadap tugas Pembimbing Kemasyarakatan dan kerja sama baik itu dengan keluarga pelaku sampai aparat penegak hukum disekitar lingkungan pelaku. Jadi kesimpulannya adalah  Pembimbing Kemasyarakatan harus melaksanakan program bimbingan yang sesuai dengan kemampuan yang dimiliki oleh klien dan juga melakukan kerja sama terhadap berbagai pihak sebagai bentuk pengawasan terhadap klien agar tidak menjadi seorang residivis
Prevalence estimation of intellectual disability using national administrative and household survey data: The importance of survey question specificity
Authors: McBride Orla , Heslop Pauline , Glover Gyles , Taggart Laurence , Hanna-Trainor Lisa , Shevlin Mark , Murphy Jamie
Published: January 2021

BackgroundVariability in prevalence estimation of intellectual disability has been attributed to heterogeneity in study settings, methodologies, and intellectual disability case definitions. Among studies based on national household survey data specifically, variability in prevalence estimation has partly been attributed to the level of specificity of the survey questions employed to determine the presence of intellectual disability.
Specific aims & methodUsing standardised difference scoring, and ‘intellectual disability’ survey data from the 2007 Northern Ireland Survey on Activity Limitation and Disability (NISALD) (N=23,689) and the 2011 Northern Ireland Census (N=1,770,217) the following study had two aims. First, we aimed to demonstrate the effects of survey question specificity on intellectual disability prevalence estimation. Second, we aimed to produce reliable estimates of the geographic variation of intellectual disability within private households in Northern Ireland while also assessing the socio-demographic, health-related and disability characteristics of this population.
FindingsPrevalence estimates generated using the more crudely classified intellectual disability Census data indicated a prevalence of 2% for the overall population, 3.8% for children aged between 0 and 15 years, and 1.5% for citizens aged 16 years or older. Intellectual disability prevalence estimates generated using the more explicitly defined 2007 NISALD data indicated a population prevalence of 0.5% for the overall population, 1.3% for children aged between 0 and 15 years, and 0.3% for citizens aged 16 years or older. The NISALD estimates were consistent with most recent international meta-analysis prevalence estimates. According to the NISALD data, the majority of those with an intellectual disability were male, lived outside Belfast, and experienced severe intellectual disability, with multiple comorbid health conditions.
DiscussionThe current findings highlight the importance of survey question specificity in the estimation of intellectual disability prevalence and provide reliable prevalence estimates of intellectual disability in Northern Ireland. The findings also demonstrate the utility of administrative data for detecting and understanding intellectual disability, and inform recommendations on how to maximise use of future intellectual disability Census data.
Estudio socioeducativo del caso de un profesor universitario en su historia de vida, en el arte, en sus albores y la academia
Authors: Vásquez Martínez Claudio Rafael , González González Felipe Anastacio
Published: January 2021

El manejo de la noción del tiempo en la narración de vida es muy flexible, pues la sensación de temporalidad constituye una alternativa utilizada con plasticidad. Basándose en las descripciones de paisajes humboldianas, el objetivo de este estudio es narrar la historia de vida de un profesor universitario según su experiencia en el arte, en los albores de su historia de vida, en los contenidos de sus libros y en su experiencia como investigador, por lo que se ha usado una metodología de investigación cualitativa de historia de vida. La pregunta formulada fue la siguiente: ¿cuál es la historia de vida de un profesor universitario en sus lugares de trabajo? En este contexto, se presenta la razón estética cotidiana de elaborar sus trabajos, y se muestran sus aspectos socioeducativos, miedos, inquietudes, fantasías y resiliencias en cada uno de sus tópicos como creador de arte. Además, se manifiesta su muy particular trayectoria académica desde el punto de vista artístico.
THE COMMON GRAMMATICAL ERRORS IN WRITING NARRATIVE ESSAY OF STUDENTS AT THE YOUTH RESOURCE CENTER, SAVANNAKHET
Authors: Phommavongsa Khamlan , Xaysetha Soulideth , Phomchaleun Somxay
Published: January 2021

The research aimed to investigate types of common grammatical errors and dominant errors in writing narrative essays of students at the Youth Resource Center, Savannakhet. This study focuses on English students at the Youth Resource Center Savannakhet. The study employed a qualitative method. A sample group was 19 (12 male and 7 female) English students who learn English as an extra class. Data collection was conducted by testing writing narrative essay. The students were requested to write descript based on their stories under the theme: unforgettable moments in life. It’s consisting their experiences, holidays, and else. The researcher was analyzed data by using a descriptive initially statistic, a complete program Excel to present the data. As the result revealed that: there were 6 categories of common grammatical errors in students’ narrative essay writing such verb-tense there were 120 times with 28%, punctuation which came 99 times with 24%, spelling happened 63 times equal 15%, preposition came with 59 times with 14%, capital letter happened 58 times with 14%, and last was article error occurred 21 times with 5%. The most dominant type of grammatical error is verb-tense came with frequency 79. This was because of the students’ lack of knowledge in grammatical writing skill.
IL FOSSILIZATION PHENOMENON ANALYSIS IN STUDENTS’ WRITING PERFORMANCE
Authors: Aini Nurul , Mufid Muhammad Khoirul
Published: January 2021

It has been widely recognized that interlanguage fossilization is the common phenomena in second language acquisition. The present study tried to investigate the students’ writing performance to find out whether interlanguage fossilization occured or not. The primary goal of this research was to give information relating to interlanguage fossilization in students’ writing performance.This research was qualitative research. The writer used observation, documentation and interview to collect the data. Purposive sampling was the technique for choosing the ten students of the sixth and the eight semester of English Education Study Program of IAIN Jurai Siwo Metro in the Academic Year of 2017/2018. The result of this research showed that there were two types of interlanguage fossilization commonly produced by students. They were syntactical fossilization and morphological fossilization. Syntactical fossilization consisted of 71, 86% and morphological fossilization consisted of 28, 14%.  Moreover, interlanguage fossilization phenomenon in students’ writing performance was caused by the students’ low English proficiency. Therefore, the students should be more active to improve their English ability.
PENYIMPANGAN PARTISIPASI MASYARAKAT DALAM PENATAAN KAWASAN CAGAR BUDAYA
Authors: Kurniawan Budi
Published: January 2021

In preserving cultural heritage based on community participation, the community engangement and their support greatly influence the outcome. This study aims to examine community participation in the activities of structuring cultural heritage carried out through the mechanism of subsidies. We employ research method using a case study approach to gain an in-depth understanding of the form and the influence of community participation in each stage of the preservation program and the factors that influence it. Based on the study, we found that there was a form of deviation of community participation, both in the implementation stage and in the post-activity utilization stage. The deviations in participation occur as a result of a mismatch between the objectives of the activity and the actual needs of the community. As for the factors that influence the occurrence of irregularities in community participation, the come from the internal form of motivation, commitment and attitude, as well as external factors in the form of activity management, and policy aspects.
TRUTH DAN POST TRUTH DALAM PERSPEKTIF AL-KINDI PADA ERA MILENIAL (MEDIA SOSIAL)
Authors: Septiyadi Cika Anugrah , Khafifah Zahrotul , Khumairoh Adesilvi Saisatul , Hidayatullah Achmad Fauzan
Published: January 2021

People have desires to search for the truth and to have broad knowledge. The internet, which was once considered as one of the media to find accurate sources of information, now has become a source of less accurate news. So there needs to be a filter in consuming news from the internet. The purpose of this study is to look at the spread of hoax news because of the  lack of awareness. The majority of social media users in the current era do not have an ethical foundation in using their right to express their opinions properly which result in hoaxes. We use literature review method to collect all the information required. In the end, we conclude that people must give an opinion by thinking about the truth first of what they have conveyed. From the truth, it can be understood that something must be justified. In accordance with the truth meant by Al-kindi that in seeking truth must to find the main source of the source itself.
Hubungan Footprint Test Terhadap Q	Angle pada Remaja Usia 12-15 Tahun di SMP Muhammadiyah 2 Gamping Yogyakarta
Authors: Anniza Meiza , MAYANGSARI RINA
Published: January 2021

Footprint test is an examination used to determine the level of the Medial Longitudinal Arch (MLA) by observing the medial border of the foot. This measurement is performed to identify deformities in the foot, such as flatfoot. This condition can become a problem if the shape of the feet does not change towards normal with age. Since the foot is the most distal region, a change in this region will be followed by a change in a more proximal region. Q angle is an important factor in assessing knee function. This research was conducted to determine the relationship between the footprint test and q angle in adolescents aged 12-15 years at SMP Muhammadiyah 2 Gamping Yogyakarta. This type of research is an analytic survey using a cross sectional approach. The population in this study were students of SMP Muhammadiyah 2 Gamping who had met the inclusion criteria. The sampling technique in this study was purposive sampling with a total sample of 51 students. From the results of the bivariate analysis with the chi square correlation test, the value of p = 0.022 (p 0.05) was obtained. This shows that Ho was rejected and Ha was accepted. Based on the objectives and research results, it can be concluded that there is a relationship between Footprint Test and Q Angle in adolescents aged 12-15 years at SMP Muhammadiyah 2 Gamping Yogyakarta. Keywords: footprint test, flatfoot, Q angle, MLA.
Peningkatkan Aktivitas Dan Hasil Belajar Matematika Materi Statistika Dengan Metode Eksperimen
Authors: Wibowo Bagus Sinung
Published: January 2021

Penelitian ini bertujuan untuk mengetahui apakah metode eksperimen dapat meningkatkan aktivitas dan hasil belajar matematika materi statistika. Subjek penelitian adalah siswa kelas VIII B SMP Negeri 3 Teras tahun pelajaran 2019/2020sebanyak 30 siswa. Penelitian ini adalah penelitian tindakan kelas dengan metode experimen yang dilaksanakan  dalam 2 siklus. Hasil penelitian menunjukkan bahwa aktivitas belajar siswa pada kondisi awal dan kondisi akhir pada materi statistika mengalami peningkatan. Siswa yang tampak tidak bergairah dan bermalas-malasan belajar berkurang dari banyak menjadi hampir tidak ada.  Hal ini disebabkan karena selama proses pembelajaran siswa terlibat aktif  bekerja melakukan praktikum sehingga tidak ada kesempatan untuk bermalas-malasan.  Hasil belajar matematika materi statistika setelah diberikan proses pembelajaran pada siklus II meningkat. Ketika diberikan ulangan harian (tes) pada kondisi awal, nilai tertinggi yang diperoleh siswa adalah 80 berjumlah 5 anak, sedang pada siklus II (kondisi akhir)  nilai tertinggi yang diperoleh siswa 100 berjumlah 5 anak.  Nilai terendah pada kondisi awal sebesar 45 dan pada siklus II (kondisi akhir) sebesar 65 yang juga meningkat. Nilai rata-rata kelas meningkat signifikan dari 55 pada kondisi awal menjadi 70 pada siklus II (kondisi akhir) yaitu sebesar 21,43 %.  Hal ini sudah memenuhi harapan untuk mencapai batas KKM (Kriteris Ketuntasan Minimal) sebesar 65.
ANALISIS KASUS KEMISKINAN DI PROVINSI KALIMANTAN TENGAH DENGAN PENDEKATAN PRINCIPAL COMPONENT ANALYSIS
Authors: Halida Annisa , Pradita Nadya Farah , Sukmawaty Yuana
Published: January 2021

According to a report by the Central Statistics Agency, the percentage of poor people in urban areas in September 2019 was 6.89%. Meanwhile, the percentage of poor people in rural areas in September 2019 was 13.10%. The data above is only a national percentage, there are still many provinces that have a poverty percentage above the national percentage, especially in Central Kalimantan Province. There are many factors that influence poverty, including education, employment status, working sector, and per capita income. This paper focuses on a study to determine the factors that have the greatest influence on poverty in Central Kalimantan Province in 2019. The results of this study simplify the poverty factor into 2 (two) factors, namely the first factor consisting of variables of education, work status, and sector. work. Meanwhile, the second factor consists of the variable per capita income for food. In addition, the greatest eigen value was obtained in the education variable of 465.67, which indicates that the education variable has the greatest influence on poverty in Central Kalimantan Province in 2019.
KEDUDUKAN SHARIA COMPLIANCE PERBANKAN SYARIAH DI INDONESIA PERSPEKTIF YURIDIS-FILOSOFIS
Authors: Adi Astiti Ni Nyoman , Tarantang Jefry
Published: January 2021

Sharia compliance is currently an important issue for sharia bank stakeholders in Indonesia. There have been many sharp criticisms from the public regarding the compliance of Islamic banks to Islamic principles, that Islamic banks in Indonesia are currently not compatible with sharia. This condition may be a positive impact of the increasingly massive socialization of Islamic banking to the public so that people are starting to become aware and have sufficient knowledge of Islamic banking, both from a juridical perspective as a regulatory framework and a solution to the legal vacuum of sharia banking regulations to ensure legal certainty, as well as a perspective. philosophical on the regulatory system that aims to create justice and benefit in Islamic banking practices.
Aplikasi Media Terkondisi Sel Punca Mesensimal dalam Terapi Penyakit Degeneratif dan Penyembuhan Luka
Authors: Widhiastuti Stefani Santi
Published: January 2021

Penyakit degeneratif seperti stroke, jantung, hipertensi, dan diabetes merupakan penyakit yang banyak dialami seseorang seiring dengan bertambahnya usia. Terapi dengan obat-obatan maupun dengan operasi telah banyak digunakan Namun pada beberapa kasus, hasilnya belum maksimal. Dengan meningkatnya ilmu pengetahuan dan teknologi, sel punca juga dikembangkan sebagai terapi regeneratif, tidak hanya untuk pengobatan penyakit degeneratif namun juga untuk penyembuhan luka akibat trauma fisik maupun penyakit yang lain. Salah satu macam sel punca yang banyak digunakan adalah sel punca mesensimal (SPM). Meskipun sel punca memiliki potensi untuk dikembangkan sebagai terapi penyakit degeneratif dan penyembuhan luka, namun proses diferensiasinya dalam tubuh belum terkontrol dengan maksimal, sehingga banyak peneliti mengembangkan penggunaan media terkondisi sel punca mesensimal (MT-SPM) sebagai terapi alternatif. MT-SPM yang merupakan medium cair tempat tumbuh SPM terbukti memiliki efek serupa dengan SPM, sehingga dapat digunakan dalam terapi penyakit stroke, jantung, diabetes, dan penyembuhan luka.