bluuebunny/crossref_metadata_2025 huggingface dataset:
Increased Frequency of the HLA-DRB1*04:04-DQA1*03-DQB1*03:02 Haplotype Among HLA-DQB1*06:02–Positive Children With Type 1 Diabetes
Authors: Ilonen Jorma , Kiviniemi Minna , El-Amir Mostafa I. , Nygård Lucas , Härkönen Taina , Lempainen Johanna , Knip Mikael ,   Finnish Pediatric Diabetes Register, Knip Mikael , Groop Per-Henrik , Ilonen Jorma , Otonkoski Timo , Veijola Riitta , Abram Alar , Aito Henrikka , Arkhipov Ivan , Blanco-Sequeiros Elina , Bondestam Jonas , Granholm Markus , Haapalehto-Ikonen Maarit , Horn Torsten , Huopio Hanna , Janer Joakim , Johansson Christian , Kalliokoski Liisa , Keskinen Päivi , Kinnala Anne , Korteniemi Maarit , Laakkonen Hanne , Lähde Jyrki , Miettinen Päivi , Nykänen Päivi , Popov Erik , Pulkkinen Mari , Salonen Maria , Salonen Pia , Sankala Juhani , Sidoroff Virpi , Suomi Anne-Maarit , Tiainen Tuula , Veijola Riitta
Published: November 2023

HLA-DR/DQ haplotypes largely define genetic susceptibility to type 1 diabetes (T1D). The DQB1*06:02-positive haplotype (DR15-DQ602) common in individuals of European ancestry is very rare among children with T1D. Among 4,490 children with T1D in the Finnish Pediatric Diabetes Register, 57 (1.3%) case patients with DQB1*06:02 were identified, in comparison with 26.1% of affected family-based association control participants. There were no differences between DQB1*06:02-positive and -negative children with T1D regarding sex, age, islet autoantibody distribution, or autoantibody levels, but significant differences were seen in the frequency of second class II HLA haplotypes. The most prevalent haplotype present with DQB1*06:02 was DRB1*04:04-DQA1*03-DQB1*03:02, which was found in 27 (47.4%) of 57 children, compared with only 797 (18.0%) of 4,433 among DQB1*06:02-negative case patients (P < 0.001 by χ2 test). The other common risk-associated haplotypes, DRB1*04:01-DQA1*03-DQB1*03:02 and (DR3)-DQA1*05-DQB1*02, were less prevalent in DQB1*06:02-positive versus DQB1*06:02-negative children (P < 0.001). HLA-B allele frequencies did not differ by DQB1*06:02 haplotype between children with T1D and control participants or by DRB1*04:04-DQA1*03-DQB1*03:02 haplotype between DQB1*06:02-positive and -negative children with T1D. The increased frequency of the DRB1*04:04 allele among DQB1*06:02-positive case patients may indicate a preferential ability of the DR404 molecule to present islet antigen epitopes despite competition by DQ602.

Article Highlights
Genetic Analysis of Obesity-Induced Diabetic Nephropathy in BTBR Mice
Authors: Keller Mark P. , O’Connor Chris , Bitzer Markus , Schueler Kathryn L. , Stapleton Donald S. , Emfinger Christopher H. , Broman Aimee Teo , Hodgin Jeffrey B. , Attie Alan D.
Published: November 2023

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in the U.S. and has a significant impact on human suffering. Leptin-deficient BTBR (BTBRob/ob) mice develop hallmark features of obesity-induced DN, whereas leptin-deficient C57BL/6J (B6ob/ob) mice do not. To identify genetic loci that underlie this strain difference, we constructed an F2 intercross between BTBRob/ob and B6ob/ob mice. We isolated kidneys from 460 F2 mice and histologically scored them for percent mesangial matrix and glomerular volume (∼50 glomeruli per mouse), yielding ∼45,000 distinct measures in total. The same histological measurements were made in kidneys from B6 and BTBR mice, either lean or obese (Lepob/ob), at 4 and 10 weeks of age, allowing us to assess the contribution of strain, age, and obesity to glomerular pathology. All F2 mice were genotyped for ∼5,000 single nucleotide polymorphisms (SNPs), ∼2,000 of which were polymorphic between B6 and BTBR, enabling us to identify a quantitative trait locus (QTL) on chromosome 7, with a peak at ∼30 Mbp, for percent mesangial matrix, glomerular volume, and mesangial volume. The podocyte-specific gene nephrin (Nphs1) is physically located at the QTL and contains high-impact SNPs in BTBR, including several missense variants within the extracellular immunoglobulin-like domains.

Article Highlights
Leptin Reduction as a Required Component for Weight Loss
Authors: Zhao Shangang , Li Na , Xiong Wei , Li Guannan , He Sijia , Zhang Zhuzhen , Zhu Qingzhang , Jiang Nisi , Ikejiofor Christian , Zhu Yi , Wang May-Yun , Han Xianlin , Zhang Ningyang , Solis-Herrera Carolina , Kusminski Christine , An Zhiqiang , Elmquist Joel K. , Scherer Philipp E.
Published: November 2023

Partial leptin reduction can induce significant weight loss, while weight loss contributes to partial leptin reduction. The cause-and-effect relationship between leptin reduction and weight loss remains to be further elucidated. Here, we show that FGF21 and the glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide rapidly induced a reduction in leptin. This leptin reduction contributed to the beneficial effects of GLP-1R agonism in metabolic health, as transgenically maintaining leptin levels during treatment partially curtailed the beneficial effects seen with these agonists. Moreover, a higher degree of leptin reduction during treatment, induced by including a leptin neutralizing antibody with either FGF21 or liraglutide, synergistically induced greater weight loss and better glucose tolerance in diet-induced obese mice. Furthermore, upon cessation of either liraglutide or FGF21 treatment, the expected immediate weight regain was observed, associated with a rapid increase in circulating leptin levels. Prevention of this leptin surge with leptin neutralizing antibodies slowed down weight gain and preserved better glucose tolerance. Mechanistically, a significant reduction in leptin induced a higher degree of leptin sensitivity in hypothalamic neurons. Our observations support a model that postulates that a reduction of leptin levels is a necessary prerequisite for substantial weight loss, and partial leptin reduction is a viable strategy to treat obesity and its associated insulin resistance.

Article Highlights
GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice
Authors: C Furber Ellen , Hyatt Karissa , Collins Kyla , Yu Xinxin , A Droz Brian , Holland Adrienne , L. Friedrich Jessica , Wojnicki Samantha , L Konkol Debra , S O'Farrell Libbey , E Baker Hana , Coskun Tamer , E Scherer Philipp , M Kusminski Christine , E Christe Michael , W Sloop Kyle , J Samms Ricardo
Published: November 2023

Recent studies have found that GIPR agonism can enhance the metabolic efficacy of GLP-1R agonist treatment by promoting both weight-dependent and -independent improvements on systemic insulin sensitivity. These findings have prompted new investigations aimed at better understanding the broad metabolic benefit of GIPR activation. Herein, we determined whether GIPR agonism favorably influenced the pharmacologic efficacy of the insulin sensitizing thiazolidinedione, rosiglitazone in obese insulin resistant (IR) mice. Genetic and pharmacological approaches were employed to examine the role of GIPR signaling on rosiglitazone-induced weight gain, hyperphagia, and glycemic control. RNA-sequencing was conducted to uncover potential mechanisms by which GIPR activation influences energy balance and insulin sensitivity. In line with previous findings, treatment with rosiglitazone induced the mRNA expression of the GIPR in white and brown fat. However, obese GIPR null mice dosed with rosiglitazone displayed equivalent weight gain to that of wild-type (WT) animals. Strikingly, chronic treatment of obese IR WT animals with a long-acting GIPR agonist (LAGIPRA) prevented rosiglitazone-induced weight-gain and hyperphagia, and it enhanced the insulin-sensitivity effect of this thiazolidinedione. The systemic insulin sensitization was accompanied by increased glucose disposal in brown adipose tissue (BAT), which was underlined by the recruitment of metabolic and thermogenic genes. These findings suggest that GIPR agonism can counter the negative consequences of rosiglitazone treatment on body weight and adiposity, while at the same time improving its insulin sensitizing efficacy.

Highlights

· Body weight gain resulting from treatment with the insulin sensitizing thiazolidinedione rosiglitazone does not require the GIPR.

· Treatment with a GIPR agonist prevents the hyperphagic and obesogenic activity of rosiglitazone.

· Activation of the GIPR improves the insulin sensitizing actions of rosiglitazone.
Leptin Reduction as a Required Component for Weight Loss
Authors: Zhao Shangang , Li Na , Xiong Wei , Li Guannan , He Sijia , Zhang Zhuzhen , Zhu Qingzhang , Jiang Nisi , Ikejiofor Christian , Zhu Yi , Wang May-Yun , Han Xianlin , Zhang Ningyang , Herrera-Solis Carolina , Kusminski Christine , An Zhiqiang , K. Elmquist Joel , E. Scherer Philipp
Published: November 2023

Abstract

Partial leptin reduction can induce significant weight loss, while weight loss contributes to partial leptin reduction. The cause-and-effect relationship between leptin reduction and weight loss remains to be further elucidated. Here, we show that FGF21 and the GLP1R agonist liraglutide rapidly induce a reduction in leptin. This leptin reduction contributes to the beneficial effects of GLP1R agonism in metabolic health, as transgenically maintaining leptin levels during treatment partially curtails the beneficial effects seen with these agonists. Moreover, a higher degree of leptin reduction during treatment, induced by including a leptin neutralizing antibody with either FGF21 or liraglutide, synergistically induces greater weight loss and better glucose tolerance in diet-induced obese mice. Furthermore, upon cessation of either liraglutide or FGF21 treatment, the expected immediate weight regain is observed, associated with a rapid increase in circulating leptin levels. Prevention of this leptin surge with leptin neutralizing antibodies slows down weight gain and preserves a better glucose tolerance. Mechanistically, a significant reduction in leptin induces a higher degree of leptin sensitivity in hypothalamic neurons. Our observations support a model that postulates that a reduction of leptin levels is a necessary prerequisite for substantial weight loss and partial leptin reduction is a viable strategy to treat obesity and its associated insulin resistance.

Article Highlights

· Weight loss agents in the GLP1R and FGF21 group induce a rapid suppression of leptin immediately upon agonist exposure.

· This leptin suppression significantly contributes to the weightloss.

· Further leptin suppression with a leptin-neutralizing antibody enhances weight loss and further improves insulin sensitivity.

· Enhanced leptin reduction leads to further reduction in hepatic steatosis and fibrosis.
Laser cladding: A high-speed-imaging examination of powder catchment efficiency as a function of the melt pool geometry and its position under the powder stream
Authors: Koti Daniel , Powell John , Naesstroem Himani , Spaccapaniccia Chiara , Voisey K. T.
Published: November 2023

This paper provides quantitative information about the paths taken by blown powder particles during laser cladding. A proportion of the powder is “wasted” by bouncing off the solid areas surrounding the melt pool. This wastage reduces the productivity and profitability of the process. In this paper, specially developed software was used to analyze high-speed imaging videos of the cladding process, to monitor the directions of powder particle flight toward and away from the melt pool area. This information has been correlated to the geometry and position of the melt pool zone for three different cladding techniques: single track cladding (A tracks), standard overlapping track cladding (AAA cladding), and a recently developed technique called ABA cladding. The results show that the melt pool geometry, and particularly the overlap between the melt pool and the incoming powder stream, has a strong influence on powder catchment efficiency. ABA cladding was found to have considerably better powder catchment efficiency than standard AAA cladding and this improvement can be explained by consideration of the geometries and positions of the melt pools and surrounding solid material in each case. As powder costs are an important factor in industrial laser cladding, the adaption of the ABA technique, and/or control of pool/powder stream overlap (e.g., by making the powder stream not coaxial with the laser beam), could improve the profitability of the process.
Rice Fallow No-Till Sorghum Using Inorganic Fertilizers in Combination with Biofertilizer Consortium: Nutrient Uptake, Yield Attributes and Economics
Authors: Reddy Kadapa Sreenivasa , Rao Ch. Pulla , Luther M. Martin , Prasad P. R. K.
Published: November 2023

A field investigation was carried out to study the influence of inorganic fertilizers along with biofertilizer consortium on the performance of sorghum under rice fallows at Agricultural College Farm, Bapatla, Acharya N. G. Ranga Agricultural University, Andhra Pradesh, India during rabi (December–April), 2018–19. There were 7 treatments tested in randomized block design (RBD) with 3 replications. Yield attributes, length of earhead (33.2 cm), number of filled grains earhead-1 (1359) and maximum protein content (9.1) were recorded higher in 125% RDF+biofertilizer consortium and remained significantly on par with 100% RDF+biofertilzers consortium treatment. Application of 125% RDF+ biofertilizer consortium application (T6) significantly increased grain and stover yields by (30.3%, 26.5%) respectively, compared to control. The same T6 treatment recorded highest nitrogen, phosphorus and potassium uptake at 30, 60, 90 DAS and at harvest in the grain and straw followed by T5 treatment. Significantly higher grain, stover, and biological yield were obtained with 125% RDF treatment compared to 75% and 50% RDF. Improvement in N, P and K uptake in grain by (53.0, 58.0 and 74.4%) and stover by (50.5, 51.8 and 50.1%) compared with control treatment. The highest gross returns (Rs. ` 71710 ha-1), net returns (`Rs.  43155 ha-1) and returns `-1 investment (1.88) was obtained with application of 125% RDF+Biofertilizer consortium treatment. When compared to other treatments, the use of 125% RDF+Biofertilizer consortium increased the production and provided economic benefits may be adapted as choice of viable alternative in the coastal Andhra Pradesh.
Video-based Analysis for Teacher Development in Physical Education
Authors: Constantinides Panos
Published: November 2023

The world in the 21st century is a world of technology and revolution in different aspects of life. The increasing desire of young people to use technology (van Laarhoven & van Laarhoven-Myers, 2006) at home, at work, and during leisure time has made industry come up with a variety of tools to be used. In such a scenario, the video recording analysis method has become a helpful tool in researchers’ and educators’ hands, allowing them to observe and assess a class, conduct pedagogy research, and so forth.  For some time, video has been used to record and analyze human movement for health issues. Physical education professionals and coaches took advantage of technology to improve their athletes’ performance using video capture. The video gave them the opportunity to analyze and inform their athletes for better performance during competition. Video-based observation has been used in several studies conducted in schools, for different disciplines and for different reasons, such as to compare different teaching styles, to compare teaching behaviors of teachers, to compare student   participation in class, or teaching effectiveness (Constantinides et al., 2013). In physical education, there is a growing interest among physical educators to incorporate digital technology in their teaching (Pyle & Esslinger, 2014; Thomas & Stratton, 2006). In this paper, however, the focus of the discussion is on how this technology may help the teacher develop and provide more effective lessons to the students. Therefore, the process of video recording is analyzed, the value-based observation is thoroughly discussed, as well as the value for the teacher who wants to develop his teaching. Furthermore, suggestions are made for physical education teachers who may use this method in the future for their own development in teaching physical education.
Alquremold Natural (AMN) for Growth Performance, Carcass Characteristics and Bacterial Growth Inhibition of Commercial Broilers
Authors: Akter Tanzina , Saha Sukumar , Arias David Diez , Chowdhury Tusar , Afrin Afifa , Lahiry Ankon , Ahmed Tanvir , Sultana Mahbuba , Rahman Shahina , Das Shubash Chandra
Published: November 2023

An experiment was conducted with 648-day-old Cobb 500 broiler chicks to evaluate the effects of Alquermold natural (AMN) on overall growth performance, carcass characteristics and inhibition of enteric bacterial growth of commercial broilers. The birds were randomly assigned to four different treatments: T0 (Control), T1 (0.5 g/kg AMN), T2 (1.0 g/kg AMN) and T3 (1.0 g/kg Mold Inhibitor (MI)), respectively. They were reared for up to 28 days. At the end of experiment, the birds’ growth performances in terms of body weight (BW), body weight gain (BWG), feed intake (FI), feed conversion ratio (FCR), survival, and meat production characteristics were recorded and calculated. Weekly fecal sample collection and microbiological count were performed to determine the bacterial load, specifically Escherichia coli and anaerobic bacteria in the broiler feces. The results showed that birds receiving 1.0 g/kg AMN had significantly higher BW and BWG (p0.01) than the control, 0.5 g/kg AMN, and MI groups. The FI and FCR of broilers were comparable in all treatment groups. There were no significant (p > 0.05) changes in meat yield parameters such as dressing percentage, neck, shank, drumstick, breast meat, thigh meat, and wing meat. However, when compared to the other dietary treatments, the bacterial load (E. coli and anaerobic bacteria) was significantly lower in the birds fed 1.0 g/kg AMN. Based on the findings, it can be concluded that feeding AMN at a rate of 1.0 g/kg may be considered for improving growth performance, maximizing feed utilization, and inhibiting bacterial load in the intestine of commercial broiler chickens.
Impactos de la deforestación y erosión hídrica de suelos en la cuenca Shocol - Amazonas
Authors: Palomino Monterola Fidel , López Ráez Luz Eufemia
Published: November 2023

El objetivo de la investigación fue identificar los impactos de la deforestación de los bosques naturales de la Cuenca Shocol. La cuantificación de la superficie de los bosques deforestados, se realizó empleando el Mapa Google Earth Pro; la determinación de la pérdida de suelos se realizó aplicando la Ecuación Universal de Pérdida de Suelos USLE, complementándose con el uso del Sistema de Información Geográfica (SIG). La determinación del volumen de agua producido en la cuenca se realizó mediante el aforo de los 10 principales tributarios. La deforestación de los bosques producida en un horizonte de 120 años, es de 24,593 ha, con una tasa media anual de 204.85 ha/año. La pérdida de suelos, aplicando la Ecuación Universal de Pérdida de Suelos (USLE) varían entre 0,01 a 30 t/ha/año; la producción de agua en la cuenca es de 15.21 m3/s. La deforestación de los bosques en la Cuenca Shocol tienen impactos negativos traducidos en: degradación de suelos, traslado de sedimentos y palizadas hacia la cuenca baja, erosión de riberas, colmatación de cursos de agua, taponamiento de sumideros e inundación de propiedades y vías de transporte. Frente la situación identificada se recomienda: restaurar los suelos de aptitud forestal y de protección deforestadas implementando proyectos de reforestación y conservación de suelos empleando especies nativas y exóticas; gestionando su financiamiento ante instancias nacionales, regionales y locales.
Cardioprotective activity of Apples Juice on Isoproterenol-Induced Myocardial Infarction in Rat
Authors: Kurniati Neng Fisheri , Nadhirah Yuthika Raihan
Published: November 2023

Myocardial infarction was local necrosis of heart tissue due to reduced oxygen supply because of theocclusion of coronary arteries. Fruits could reduce the risk of developing obesity and CVDs. Severalstudies have shown that apples had a strong cardioprotective effect. This study aimed to understandthe cardioprotective activity of two variants of apples, e.g., Fuji and Malang, on isoproterenol-inducedmale Wistar rats. The cardioprotective activity test was carried out for 14 days, all testing group exceptnegative control, was induced by isoproterenol. The results of testing cardioprotective activity showedthat Fuji Apple juice and Apel Malang juice had the same capability to inhibit increasing cardiacbiomarkers value (CK and CK-MB) with the highest inhibition was 79,56% and 73,08% for FujiApples, 69,18% and 43,04% for Apel Malang. The result of the cardiac histopathology examinationshowed that both Apples could prevent cardiac tissue damage. All juice Apple doses had the samecardioprotective activity.
WOMEN’S EXPANSION IN REGIONAL HEAD ELECTIONS IN MEDAN CITY 2020 (CASE STUDY ON THE AKHYAR-SALMAN COUPLE)
Authors: Arfan Rocky , Azzahra Dinda , Suryanef Suryanef , Rafni Al
Published: November 2023

The role of women as political elites is increasingly important, which makes gender inequality widespread. This study examines the expansion, role, and contribution of DPD women of the Partai Keadilan Sejahtera (PKS) in the 2020 Medan City regional head elections with a case study on the Akhyar-Salman couple. Qualitative research was conducted by collecting data on the role of female PKS party members and leaders in winning the Akhyar-Salman pair through in-depth interviews with research subjects. sample determination using a purposive sampling technique. All data were processed descriptively. The results showed that the expansion of women in improving the quality and quantity of regional elections in Medan City is significant; this is indicated by the contribution of women’s political elites in mobilizing the implementation of campaigns in the community and attracting public interest from upstream to downstream to introduce the Akhyar-Salman couple. Women’s political elites have functions and responsibilities in winning candidate pairs through door-to-door campaigns to each household, creating work programs that attract women to join, such as carrying out women’s recitation (dakwah), helping communities affected by disasters, and carrying out approaches to the ulama. In addition, the most prominent expansion of women lies in the gender equality program and equal access to information, which have the most decisive influence on the campaign process. The work program launched by the mayoral and deputy candidate pairs is the result of preliminary studies of the community and data collection by the DPD PKS women’s political elites. Finally, the Japuan program (women’s network) indicates that voter accommodation and navigation can be appropriately managed by disseminating information related to candidate pairs by political elites from the PKS party.
MEDIA DISCOURSE AND INTERNAL CONFLICT OF JAVANESE POWER IN YOGYAKARTA
Authors: Wulan Roro Retno , Nugroho Catur , Nastain M.
Published: November 2023

This paper attempts to reveal how the local media, Kedaulatan Rakyat, produces discourse on the Yogyakarta palace’s internal conflict involving Sri Sultan Hamengku Buwono X and his siblings. The Special Region of Yogyakarta as a province in Indonesia has a special government system that is different from other regions. The governor of Yogyakarta is not elected by the people like in other regions in Indonesia but is determined by the DPRD based on who serves as the King of the Yogyakarta Palace. This phenomenon becomes interesting when there are differences of opinion among the people and within the Yogyakarta Palace regarding the acceptance of women leaders. The conflict began to arise when Sultan Hamengku Buwono X issued the Sabda Tama and Sabda Raja (Sabda Raja) which were interpreted as the Sultan’s way to pave the way for his daughter to become heir to the throne. The Sultan’s younger siblings opposed the female king to rule in Yogyakarta, so an internal conflict arose. The research method used is a qualitative method with a critical discourse analysis approach using the Norman Fairclough model to analyze news texts related to the Yogyakarta Palace’s internal conflict from the Kedaulatan Rakyat Daily. From the results of the research, it was found that the Kedaulatan Rakyat Daily produced discourses on internal conflict in the Yogyakarta palace by representing the ideology and interests of Sultan HB X’s younger siblings. This local daily newspaper also commodified internal conflict in the Yogyakarta palace as events that were produced and disseminated to the public for the benefits media economy.
Polymer gel amended sandy soil with enhanced water storage and extended release capabilities for sustainable desert agriculture
Authors: Krishnan Mohan Raj , Alsharaeh Edreese Housni
Published: November 2023

Herein, we report a facile preparation of super-hydrophilic sand by coating the sand particles with cross-linked polyacrylamide (PAM) hydrogels for enhanced water absorption and controlled water release aimed at desert agriculture. To prepare the sample, 4 wt% of aqueous PAM solution is mixed with organic cross-linkers of hydroquinone (HQ) and hexamethylenetetramine (HMT) in a 1:1 weight ratio and aqueous potassium chloride (KCl) solution. A specific amount of the above solution is added to the sand, well mixed, and subsequently cured at 150 °C for 8 h. The prepared super-hydrophilic sands were characterized by Fourier-transform infrared spectroscopy (FT-IR) for chemical composition and X-ray diffraction (XRD) for successful polymer coating onto the sand. The water storage for the samples was studied by absorption kinetics at various temperature conditions, and extended water release was studied by water desorption kinetics. The water swelling ratio for the super-hydrophilic sand has reached a maximum of 900% (9 times its weight) at 80 °C within 1 h. The desorption kinetics of the samples showed that the water can be stored for up to a maximum of 3 days. Therefore, super-hydrophilic sand particles were successfully prepared by coating them with PAM hydrogels, which have great potential to be used in sustainable desert agriculture.
Jáchymov: Borders of Oblivion
Authors: Kulmiński Robert
Published: November 2023

The remarkably dynamic history of the small Czech town of Jáchymov provides the possibility of tracing memory, forgetting and recalling through constant rewriting and negotiation – both of a place of the individual memories, as well as the hierarchy of the events which are worthy of being remembered, and those that would rather be forgotten. German, Soviet, and Czech presence here cross with the spa and military nature of this place and its martyrological memory, on one side of the transfer of the German population shortly after World War II, and on the other one the political prisoners of the 1950s, who were forced into slave labor in the local uranium mine. All of these layers still remain today – referring to the title of the book by Karolina Ćwiek-Rogalska – remembered in Jáchymov's summer landscape, in which the air is breaking the image of reality, making it fluid, and somewhat elusive. And it is this variety of the layers of memory, recalling, and oblivion, which I would like to identify and describe in my article.
Twinned Renewable Energy Accumulation: Case of Wind and Hydro Energy
Authors: Brence Katarina , Kudurs Edgars , Valters Kārlis , Blumberga Dagnija
Published: November 2023

Renewable energy sources (RES) are the key element of sustainable energy systems. To accommodate the intermittency of wind (and solar) electricity generation, energy storage is critical. The aim of the study was to evaluate the potential of wind energy storage in the existing hydropower plant reservoirs in Latvia with the pumped hydroelectric energy storage (PHES) technology, considering the current and projected future wind energy capacities. An algorithm was developed and used for data aggregation and analysis, calculations, and forecasting. The three River Daugava hydroelectric power plants are the largest electricity producers in Latvia, and their generation capacity depends on seasonal variations. Currently, Latvia's electricity generation from RES is the highest during the spring season when maximum hydropower potential is utilized. However, wind energy has a potential to grow and could supplement hydropower throughout the year. Decreasing the existing administrative procedure heaviness to faster achieve the climate neutrality targets and energy autonomy by increasing RES development in Latvia is a way to create sustainable energy production. A rational future scenario in Latvia is to expand wind parks and integrate pumped hydroelectric energy storage systems in the existing cascade hydropower plants.
Earlier Management Practice and Thinking: Hediya Peoples’ Indigenous Management Philosophy in the Construction of “Mud-Hut” In Central Ethiopia Regional State
Authors: BETABO GOGSIDO Sheref
Published: November 2023

The main problems of research are: the impact of social environment on human behaviour has contributed to the debate against the management view of universal applicability, and also there are multiple challenges for the African indigenous management theories development. The research aims to have an indigenous management philosophy of the Hediya people in Ethiopia in their mud-hut construction. The study is carried out using the metaphoric method of the qualitative research approach. The researcher collected metaphoric data from the Hediy-nefra of Lemo community where researcher was born, and through his observation while living in his lifetime. The findings include the strongest essence of team work, strategic recruitment and selections, motivating of employees through financial and non-financial factors such as team environment and work design. Particularly, the finding includes: continuing of employees’ benefit for the ex-employees is important not only for them but also for the organisation on the future; employees are enforced to give focus on the work quality not to have current work related benefits but also it is a means of getting employment and finance in the future. In the management idea of Hediya peoples’ indigenous hut building system, the relationship of an organisation with competitors was being practiced positively and helping each other, so that it needs to be enforced. Besides, the good quality of current work will attract a lot of employers other than current workers/organisation with referent of previous hut construction quality. The hut construction concept of Ethiopians’ management practices should be verified.
Democracy in Research Circles to Enable New Perspectives on Early Childhood Education and Didactics
Authors: Månsson Annika , Rubinstein Reich Lena
Published: November 2023

The aim of this article is to examine aspects of democracy derived from participation in so-called research circles, and to discuss participatory and democratic ideas arising in those circles as they relate to perspectives on Early Childhood Education. This paper draws its argument mainly from material recorded from two research circles — one on Gender and the other on New subject didactic challenges in preschool. The analysis was based on the separate data from the two research circles and on a comparison between them. It is a theoretically governed approach based on Klafki’s critical constructive didactics and Biesta’s critical discussion on education and democracy in relation to the rise of neoliberalism. Larsson’s three aspects of democracy in relation to study circles have been used: equal participation, horizontal relations and knowledge that informs standpoints. The diversity between the circles resulted in variations concerning form and content that could be discussed as related to democracy aspects.
Digital Transformation Of Subak Management In Bali Through GIS Implementation
Authors: Achmadi Shilta Inda Qurroti A'yun , Basco Anjela Faye M. , Sudana Oka , Rusjayanthi Ni Kadek Dwi
Published: November 2023

Subak is a customary law society with socio-agrarian-religious characteristics, consisting of a group of farmers who manage the irrigation of rice fields or paddies. The agricultural irrigation system in Bali or Subak was officially recognized as one of the world's cultural heritages in 2012 by UNESCO. Many Subak data still rely on traditional recording systems, making it crucial to have a digital transformation using an information system platform capable of collecting data on Subak and providing related information about Subak in the Bali Province. To address this problem, a mobile-based Geographic Information System (GIS) that encompasses information about Subak is developed. The data collection method used in this research includes literature studies and questionnaires. The result obtained from this research is an Android mobile application tested using Black Box Testing. All tests were successfully met according to the testing criteria that have been established.
Refining Content-Based Segmentation for Prediction of Coffee Bean Quality
Authors: Irianto Suhendro Yusuf
Published: November 2023

Coffee has substantial economic value and is a key foreign exchange source for numerous nations, including Indonesia. Moreover, it is a primary livelihood for many of the country's farmers. Recently, there have been challenges in accurately predicting the quality of coffee beans, primarily due to time, inconsistency, and imprecision issues. Consequently, this study delves into the application of region-growing segmentation and content-based image retrieval (CBIR) techniques to enhance the prediction of coffee bean quality. The proposed hybrid approach, which combines region growing and CBIR methods, aims to improve the precision for forecasting cacao bean quality. Additionally, the research introduces an automated tool that employs these hybrid techniques for quality prediction. The study conducted experiments using a dataset of 400 premium and 400 low-quality coffee beans sourced from the University of Syiah Kuala in Indonesia. The results of the experiments demonstrate a commendable precision rate of 85.4%, showcasing significant improvement compared to certain previous studies.
The Optimization of the ARP Poisoning Attack Detection Model Using a Similar Approach Based on NetFlow Analysis
Authors: Atmojo Yohanes Priyo , Hostiadi Dandy Pramana , Susila I Made Darma , Liandana Made , Pradipta Gede Angga , Ayu Putu Desiana Wulaning
Published: November 2023

Information security and threats are a concern in the cyber era. Attacks can be malicious activities. One of them is known as ARP poisoning attack activity, which attacks by falsifying a computer's identity through illegal access to retrieve confidential information in a target computer. Besides, it has also caused service deadlocks in the network. Previous studies have been introduced for the ARP Attack Detection model using rule-based and mining-based. Still, they cannot show optimal detection performance and obtain high false positive results. This paper proposed a detection model for ARP poisoning attacks using a similarity measurement approach adopting cosine similarity. The goal is to obtain measurements of host activities similar to ARP poisoning attacks. The experiment results showed that the model got an accuracy of 97.25%, recall of 96.43%, and precision of 81% with a similarity threshold value of 0.488. Comparison results with previous studies showed higher detection accuracy than previous studies and some classification methods. It shows that the model can improve intrusion detection performance and facilitate network administrators to analyze ARP poisoning attacks in computer networks.
Numerical-Computational Model for Dynamic Nonlinear Analysis of Frames With Semi-Rigid Connection Considering the Damping Effect
Authors: De Souza Luiz Antonio Farani , Verdade Lucas Lauer
Published: November 2023

Objective: the scope of this work is to present a numerical-computational model for transient dynamic nonlinear analysis of frames with geometric nonlinearity and semi-rigid connection.
 
Methodology: the equation of motion, which describes the structural dynamical system, is solved by the a-Generalized direct integration method associated with the standard Newton-Raphson method. The structures are discretized through the co-rotational formulation of the Finite Element Method considering the Euler-Bernoulli beam theory. The semi-rigid connection of structural members (beam-column and beam-support) is simulated by a connection element with zero length, which is described in terms of axial, translational and rotational stiffness.
 
Results and conclusion: From the numerical results of three structural systems (bi-fixed beam, L-shaped frame, and single-story frame) obtained with the free Scilab program, it is concluded that the definition of the type of connection is an important factor to be considered in the analysis of frames subjected to dynamic loads. Furthermore, structural damping, which is a measure of energy dissipation, drives the structure from a vibrating state to a resting state.
 
Research implications: Structural Engineering has been designing systems that cannot be analyzed and dimensioned without dynamic effects being considered. lack of knowledge of the levels and characteristics of the dynamic response can lead to system failure during the application of repetitive loading due to accumulation of structural damage. In this sense, the numerical model can represent a valuable engineering tool when it comes to the dynamic analysis of plane metallic structures with geometric nonlinearity.
PENGGUNAAN GAS AIR MATA DALAM PENGAMANAN PERTANDINGAN SEPAKBOLA DALAM PERSPEKTIF HUKUM POSITIF DI INDONESIA
Authors: Putra Dery Irawan Aditya , Zeinudin Moh. , Fithry Abshoril
Published: November 2023

Result observationaling to point out 1. FIFA'S order and also PSSI was clear about sharp weapon purpose and Lachrymator may not be brought in evenless is utilized at deep stadium and also stadium outboard, that thing most decants deep section 19b. " No. fire arms or crowd control gases shall be carried or used  (May not take in or utilizes firearm or lachrymator),", 2. forbidden FIFA order marks sense lachrymator, therefore law accountability did by football chairman or at so-called Indonesia with PSSI and Panita Is Executor or Panpel. But, since at oft lachrymator purpose Indonesia did by agency, therefore agency is mustinya even do law accountability as it were has already been brought together deep Section 13 Kapolri's regulations Number 1 Years 2009. FIFA'S conclusion and PSSI was clear forbidden deep water gas purpose because will trouble eye health stops the show.
PERTANGGUNGJAWABAN PELAKU USAHA ATAS KERUGIAN WISATAWAN MENURUT UNDANG-UNDANG NOMOR 10 TAHUN 2009 TENTANG KEPARIWISATAAN
Authors: Ababil Maulana Rouf , Sugiarti Yayuk , Fithry Abshoril
Published: November 2023

According to the Law of the Republic of Indonesia Number 10 of 2009 concerning tourism, it is stated that tourism is a variety of tourist activities and is supported by various facilities and services provided by the community, businessmen, government and local governments. The formulation of the problem of this thesis is how is the form of legal protection for tourists and how is the form of responsibility of tourism business actors towards tourists. The purpose of writing this thesis is to find out and get a solution from the formulation of the problem. The research method in writing this thesis is normative by using a statutory approach with several sources of primary and secondary legal materials, as well as tracing legal materials through legislation and other literature. In the context of legal protection for tourists, what needs to be protected is the rights of tourists. Every tourist has the right to comfort, safety and to get fair treatment and the best possible service from the country where the person concerned visits the tourist spot. Countries where tourists visit must provide security and safety for tourists based on existing laws and regulations. Law Number 10 of 2009 concerning Tourism already regulates the rights and obligations of tourists and tourism entrepreneurs. Article 20 regulates the rights of tourists, including: accurate information about tourist attractions, tourism services in accordance with standards, legal protection and security, health services, protection of personal rights, and insurance protection for high-risk tourism activities.
First data on rare earth mineralization in acid rock varieties of the Shatak complex (Southern Urals)
Authors: Kovalev S. G. , Kovalev S. S. , Sharipova A. A.
Published: November 2023

Research subject. Acid rock varieties of the Shatak complex were studied. Materials and methods. The reseach object included the previously unknown abundant mineralization represented by rare earth minerals. The concentration of petrogenic oxides was determined by the X-ray fluorescence method at the IG UFRC RAS (Ufa) using a VRA-30 spectrometer (Carl Zeiss, Germany) with an X-ray tube with a W-anode (30 kV, 40 mA). The amount of rare earth elements in the rocks of the studied area was determined by the ICP-MS method at the Central Research Institute of VSEGEI (St. Petersburg). The mineralogy was studied using a Tescan Vega Compact scanning electron microscope equipped with an Xplorer Oxford Instruments energy-dispersive analyzer (IG UFRC RAS, Ufa). Results. The studied rocks were diverse in chemical composition, varying from alkaline varieties (trachydacites) to low-alkaline rhyolites. These rocks belong to a highalumina type characterized by potassium specialization and a low agpaitic coefficient. It is assumed that the felsic varieties are subvolcanic formations, and the term “rhyolites” in this case characterizes the chemical composition of the rocks, but not their genesis. The amount of rare earth elements in the studied rocks is subject to significant fluctuations, varying from 60.81 g/t to 1625.39 g/t; moreover, their distribution is characterized by significant differentiation. In general, the rocks belong to a contrasting basalt-rhyolitic series, and their genesis is due to the differentiation of magma in the intermediate chamber. Numerous rare-earth minerals were found in the rocks, inlcuding allanite-(Ce), monazite-(Ce), monazite-(La), nioboeshinit-(Y), aeschinite-(Y), talena-(Dy), talena-(Nd), synchisite-(Ce) and Ce–La–Fe oxide. Conclusions. The presence of paragenetic associations of rare-earth minerals, such as allanite-(Ce) + aeschinite-(Y) + nioboaeschinite-(Y) and allanite-(Ce) + talena-(Dy) + talena-(Nd), indicate the formation of rare-earth mineralization in the course of a single process. The described type of mineralization has no analogues on the western slope of the Southern Urals, which substantiates the need for further research.
Highlights on the Bio-Economic Reference Points for Fisheries Management and Planning
Authors:   Centro Interdisciplinario De Ciencias Marinas, Chavez Ernesto A
Published: November 2023

A brief discussion on the main processes ruling the exploitation of fish stocks is given. Comments on the content of main issues in stock assessment are provided.
An Evaluation of Two Rearing Densities During the Initial Rearing of Landlocked Lake Oahe Fall Chinook Salmon
Authors:   South Dakota Department Of Game, Voorhees Jill M
Published: November 2023

Landlocked fall Chinook salmon Oncorhynchus tshawytscha were at an initial density of either 0.96 or 3.76 kg/m3 shortly after feed training.
A Retrospective Study on the Application of Guided Rehabilitation Training In the Rehabilitation of Children with Peripheral Facial Paralysis
Authors:   Key Laboratory Of Rehabilitation Medicine, Yang Lin
Published: November 2023

To observe the clinical efficacy of guided rehabilitation training in the treatment of peripheral facial paralysis in children.
Effectiveness of Muscle Relaxatnt Terapy in the Treatment of Tmj Dysfunction
Authors:   Department Of Orthodontic And Prosthetic Dentistry, Kostiuk Tetiana
Published: November 2023

Our study allowed us to trace and analyze changes in the chewing muscles of patients that occur during the treatment of Tempoal-Mandibular Joint dysfunction (TMJ) and indicate its effectiveness.
Aplasia cutis congenita on the scalp: case report and review of literature
Authors: Castro Tiago , Pereira Carolina , Oliveira Queila , Nunes Leandro
Published: November 2023

INTRODUCTION: Congenital Cutaneous Aplasia is a rare skin lesion, usually restricted to the scalp, characterized by a focal absence of cutaneous tissue, sometimes involving muscles, periosteum and dura mater. There are several etiologies described, such as poor neural tube closure, vascular anomalies, pressure necrosis in the localized embryo, among others. METHOD: We report the case of a newborn at the first physical examination with an annular vesicular lesion, in the occipital region, of 0.8 cm in greater diameter, with hyaline / bloody content and peripheral hyperemia. After a clinical diagnosis was made, we opted for conservative treatment with topical application of hydrogel until complete healing. The patient was then discharged from the hospital, with subsequent return and resolution of the lesion at 30 days of life. CONCLUSION: Congenital cutaneous aplasia is a rare disease, which can affect only the scalp, but can also present with the absence of part of the skullcap, which increases mortality due to the increased risk of complications such as liquor fistula, meningoencephalitis and bleeding.
Neonatal necrotizing enterocolitis: case report and literature review
Authors: Vasques Karla , Santos Érika , Aleixo Neideana
Published: November 2023

Neonatal necrotizing enterocolitis (NEC) is a syndrome characterized by inflammation and ischemic necrosis of the gastrointestinal tract that can course with variable clinical manifestations: such as abdominal distension, bilious vomiting, hematoquezia, frequent gastric waste, decreased hydro-air noises, fecal changes. The condition is usually associated with systemic signs (pallor, apnea, hypoactivity, dysthermias). NEC can manifest with partial intestinal necrosis and have complete recovery, requiring only clinical treatment. Case report: newborn (NB) of T.A.A., female, premature (33 weeks and 5 days), extremely low weight (888g), APGAR 8/9, referred to the Neonatal Intensive Care Unit (ICU NEO). On the 1st day of life, he presented significant abdominal distension and bilious debt by the orogastric tube (SOG). It eliminated meconium after rectal stimulation, with 43 hours of life. He maintained abdominal distension until the 10th day of life, progressing, with progressive improvement (reduction of abdominal distension, change in the aspect of the debt by SOG), after the institution of adequate therapy. On the 11th day of life, he started a minimal enteral diet, progressing gradually, achieving success in diet progression. Enterocolitis is one of the most frequent gastrointestinal emergencies in neonates, most frequently affecting premature newborns, especially those born with very low birth weight. Studies indicate the recent increase in the incidence of NEC in NEO ICUs, in several countries, due to the increased survival of premature newborns. Therefore, there is a need for a greater dissemination of knowledge about the pathology; mainly among health professionals who work in these units.