bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk Factors for Mortality Among Patients on Hemodialysis in India: A Case-Control Study
Authors: Sankarasubbaiyan Suresh , Pollock Carol A. , Anandh Urmila , Kasiviswanathan Savitha , Shah Kamal D.
Published: August 2024

Background

Mortality in hemodialysis (HD) exceeds that of many solid organ cancers, despite advancements in care. This study was conducted to understand mortality in a large dialysis network of Indian HD patients and attempt to elucidate risk factors for mortality.

Materials and Methods

We performed a case-control study of deaths among patients undergoing HD across 203 centers in India from January 1 to March 31, 2021 with an age-matched control of survivors. We reviewed demographic, dialysis, clinical, and socioeconomic factors.

Results

Out of 17,659 patients on dialysis, 554 cases (non-survivors) and 623 age-matched controls (survivors) patients were followed up. The mean age was 54.9 ± 13.8 years, 70.5% (391) of them were males. Gender, BMI, dialysis frequency, HD vintage time, history of diabetes, and heart failure were similar between non-survivors and survivors. Lower education level, payment under public insurance, dialysis facility under a public-private partnership, vascular access via catheter, hemoglobin <8 g/dL levels, serum albumin <3.5 g/dL were significantly higher, hospitalizations in 3 months prior to death were more frequent among non-survivors.

Conclusion

Factors including Hb <8 g/dL, temporary catheter, serum albumin less <3.5 g/dL, lower educational status, and dialysis under public insurance are associated with poorer survival in our population. Our findings have implications for designing interventions needed to improve outcomes for evolving policy and public-payer systems.
Osztálytabló : Az egyházi elhárítás munkatársai a nyolcvanas években
Authors: Tabajdi Gábor
Published: August 2024

Tanulmányomban egy állambiztonsági részleg állományát, az 1990-ben megszüntetett BM III/III-1 Osztály munkatársait mutatom be. Azt kívánom körüljárni, hogyan lehet az egykori hivatásos (tartó)tiszteket azonosítani, illetve ez a folyamat szélesebb értelemben miként segítheti a történeti megismerés folyamatát.1 Az osztálytablón szereplő egyházi elhárítók nyolcvanas évekbeli tevékenységét különböző forrástípusok segítségével próbálom megvilágítani. Az eltérő megközelítések kapcsán felmerülő problémákat és lehetőségeket, illetve a dokumentálhatóság határainak kérdését feszegetve új vizsgálati perspektíva alkalmazására teszek javaslatot.
Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the Androgen Receptor
Authors: Ahmed Ikhlas M. M. , Rofe Adam , Henry Martyn C. , West Eric , Jamieson Craig , McEwan Iain J. , Beveridge Rebecca
Published: August 2024

Intrinsically disordered proteins (IDPs) are important drug targets as they are key actors within cell signalling networks. Accordingly, their dysregulation is highly implicated in a range of disease states. However, the conformational plasticity of IDPs renders them challenging to characterise both experimentally and theoretically, which is a major bottleneck in the development of small molecule drugs that bind to IDPs and modulate how they behave. In relation to this, ion mobility mass spectrometry (IM-MS) is a useful tool in the investigation of IDPs, as it can reveal their conformational preferences when they are ionised from different conditions. It also has the potential to offer important insight to the drug discovery field as it can measure binding stoichiometry and unveil conformational shifts of IDPs exerted by the binding of small drug-like molecules, which will affect their associated pharmacology. In the current study, we have used IM-MS to investigate the effect of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the Androgen Receptor (AR-NTD). Despite structural heterogeneity rendering the NTD a challenging region of the protein to drug, this domain is responsible for most, if not all, of the transcriptional activity. We quantify the stoichiometry of EPI-001 binding to various constructs that correspond to functional domains of the AR-NTD, and show that it binds to separate constructs containing transactivation unit (TAU)-1 and TAU-5, respectively, and that 1-2 molecules bind to a larger construct containing both sequences. We also identify a conformational shift upon EPI-001 binding to the TAU-5 containing construct, and only to a much lesser extent with TAU-1. This work provides novel insight on the interactions of EPI-001 with the AR-NTD, and the structural alterations that it exerts, and positions IM-MS as an informative tool that will enhance the tractability of IDPs, potentially leading to better therapies.
An Open-Source Implementation of the Scaffold Identification and Naming System (SCINS) and Example Applications
Authors: Petrov Kamen , Bender Andreas
Published: August 2024

Organizing and partitioning sets of chemical structures is of considerable practical significance e.g. in compound library analysis and the post-processing of screening hit lists. Approaches such as unsupervised clustering are computationally demanding and dataset-dependent; on the other hand, rule-based methods, such as those based on Murcko scaffolds, have linear time complexity, but are often too fine-grained, leading to a large number of singletons or sparsely populated classes. An alternative rule-based method that seeks to achieve an optimal balance when grouping compounds into sets is the ‘Scaffold Identification and Naming System’ (SCINS). To facilitate public use of this previously published method, here we provide an open- source Python implementation of SCINS, dependent only on RDKit. We show that SCINS can be useful in identifying sparsely and densely populated regions in chemical space in large databases, here exemplified with Enamine REAL Diverse and ChEMBL. We find that Enamine REAL Diverse covers a much smaller SCINS space relative to ChEMBL; whereas the opposite is true when Murcko and generic Murcko scaffolds are considered. Additionally, we show that SCINS can result in chemically intuitive grouping of medium-sized sets of bioactive compounds, which can be useful in compound selection from virtual screening campaigns as well as post- processing of experimental hit lists. Hence in this work we both provide an open-source implementation of SCINS, as well as its characterization with relevant use cases.
Robust catalyst assessment for the electrocatalytic nitrate reduction reaction
Authors: Pathak Devesh Kumar , Jana Rajkumar , Bello Ruth , White Kelly , Stoerzinger Kelsey A
Published: August 2024

The electrochemical nitrate reduction reaction (NO3RR) shows great promise for the distributed conversion of waste nitrate to ammonia. We highlight complexities of the reaction mechanism and possible waste feedstocks, and advocate best practices for robust measurement of catalyst activity, selectivity, and Faradaic efficiency in this burgeoning field. While fundamental studies of the reaction mechanism and environment are still needed, rigorous performance assessment in well-defined conditions will best enable catalyst design. Progress will be most dynamic and responsive with shared community standards that enable comparison between groups while reflecting the complexity of possible feedstocks
Development and Validation of Assay Method for the Estimation of Moxifloxacin in Bulk and Pharmaceutical Formulations by RP-HPLC.
Authors: siraj zahid , Adil omair , Amin Bakht , Tahiri Iftikhar
Published: August 2024

A simple, specific, and isocratic reversed phase-high performance liquid chromatography (RP-HPLC) method with UV detection at 293 nm and column Agela Technology, Venosil XBP C18, (Venosil XBP, 4.6mm×250mm, 10µm) was developed and validated for analysis of moxifloxacin hydrochloride (MOXI) in presence of its degradation products. The retention time of the MOXI was found at 9.99 min. A mobile phase consisting of phosphate buffer and methanol (18:7 v/v) at flow rate of 1.3mL/min, at temperature 50°C maintained by using column oven in the study. While 0.1N HCl was used as diluent. The calibration curves were linear with correlation coefficient (R2) of 0.999. The detection and quantification limit were found as 0.029 µg mL-1 and 0.095 µg mL-1 respectively. The method was validated in accordance with International Conference on Harmonization (ICH) guidelines. The proposed method was found sensitive, specific and was successfully applied for the estimation of MOXI in pharmaceutical formulations. Innumerable analytical measurements are made for the estimation of MOXI in pharmaceutical formulations, so the proposed analytical method leads to provision of cost effective by using low-cost diluents and the reagents.
LiCOMPGNN - Lightweight Contextual Message Passing for Crystalline Materials Property Prediction
Authors: Humphreys Zachary , Evangelopoulos Xenophon , Gerolymatos Stavros , Pyzer-Knapp Edward O. , Cooper Andrew I.
Published: August 2024

Graph neural networks have recently met huge success in various inference tasks including materials property prediction amongst many others. Nevertheless, having an inherently locally-based representation capacity as they do, global representation of materials' structures can only only be achieved by expanding the model complexity which in turn scales up training times and memory consumption. In this work we focus on efficiently capturing global interactions ``in-model'', through long-range edge attentions with minimal memory footprints. We introduce a novel ``contextual'' message passing scheme that better captures global interactions by attending on edges from both the local and global environment of each node in an edge-update fashion. The performance of the proposed model (LiCOMPGNN) is tested on a diverse set of materials property prediction benchmarks and demonstrates competitiveness against state-of-the-art models in several prediction tasks whilst being an order of magnitude smaller in terms of trainable parameters. We further augment the framework to a multiplex graph setting for solid-state data with reciprocal space features taken into account in a multimodal message passing regime. We demonstrate the representation capacity of the proposed variant along with others in maintaining supercell invariance in crystalline property prediction tasks.
A Three-Pronged Computational Approach for Evaluating Density Based Semi Empirical Equations of Supercritical Extraction Process and Data
Authors: Srinidhi Srinidhi
Published: August 2024

Software programs for parameter estimation, phase visualization and predictive modeling of supercritical extraction process and data using algorithms is presented in this work. A contextually appropriate, iterative, ordinary least squares estimation and selection method is developed for estimating model coefficients of density based semi empirical model equations associated with this process and data. Visualization of the phase behaviors projected by the specific density based semiempirical model equation(s) is also performed iteratively by plotting three-dimensional surfaces involving the state variables and solute solubility mole fraction. Predictive modeling of input empirical data has been implemented using three supervised machine learning algorithms (Multilayer perceptron, K-nearest neighbors and Support vector regression). Hyperparameter optimization of the machine learning algorithms is performed prior to prediction. Detailed analysis of the prediction is conducted by using standard scoring metrics and descriptive charts. Theoretical inference and discrepancies regarding the predicted window of maximum/optimal solubility, modeling efficiency, vapor liquid equilibrium and phase behaviors projected by the model equations have been elucidated from the program outputs. In summary, these programs are unique, accurate, reliable and simple computational tools for evaluating/designing density based semiempirical equation(s) of supercritical extraction process and associated data.
Graph-Based Modeling and Molecular Dynamics for Ion Activity Coefficient Prediction in Polymeric Ion-Exchange Membranes
Authors: Naghshnejad Pegah , Theis Marchan Gabriela , Olayiwola Teslim , Romagnoli Jose , Kumar Revati
Published: August 2024

The partitioning of ions between polymeric ion-exchange membranes (IEMs) and the surrounding liquid is governed by the activity coefficients of the ions, which, in turn, significantly impact various ion transport processes within these membranes, notably conductivity. This study introduces a computational framework to predict ions' activity coefficients in charged Ion Exchange Membranes (IEMs). This method employs a machine learning (ML) model using molecular-scale characteristics obtained from Molecular Dynamics (MD) simulations, particularly emphasizing solvation properties within the context of IEMs. Specifically, the framework utilizes Graph Convolutional Networks (GCN) to establish connections between the chemical structure of the polymer and the molecular-level attributes. This ultimately leads to determining macroscopic attributes, such as the activity coefficient, across a range of IEM materials, having random copolymer and block copolymer systems. Furthermore, saliency maps were generated to identify the critical features of polymer molecules that correlate with ion activity coefficients. The graph-based prediction strategy proved highly accurate in predicting ion activity coefficients within IEMs, even with relatively small training datasets.
Data-driven Screening and Discovery of Metal- organic Frameworks as C2 Adsorbents from Over 900 Experimental Isotherms
Authors: Rivera Matthew , Terrones Gianmarco , Lee Tae Hoon , Smith Zachary , Kulik Heather
Published: August 2024

The separation of ethylene from ethane accounts for almost 100 million tons of CO2 emissions annually and 0.3% of global primary energy usage. Replacing current cryogenic distillation units with adsorption separation units, especially for the minor component of ethane, would enable significant efficiency gains. Metal-organic frameworks (MOFs) are well-suited for adsorption separation due to their high surface areas and tunable chemical properties; exploring all possible MOFs is a daunting experimental challenge, motivating in silico screening with machine learning models. We present a database of 948 experimentally measured pure-component C2 isotherms from 192 MOFs gathered from the literature and use it to train machine learning models to predict MOF ethane and ethylene uptake across a range of temperature and pressure conditions. The models have high accuracy in interpolative tasks (mean absolute error ~0.05 mmol/g) when trained on only 20% of available data. Performance on unseen structures was also reasonably accurate with MAEs ~0.7 mmol/g. We apply the models to screen the CoRE ASR 2019 database and identify the most promising candidates. Several MOFs containing lanthanide metals were predicted to have high ethane selectivity, suggesting that this class of MOFs may be worth further investigation. Feature importance analysis suggests that MOF SBU design and optimizing the process conditions at which the sorbent will operate are critical for enabling ethane-selective separation. We synthesize a MOF predicted to exhibit high ethane selectivity and experimentally validate qualitative agreement of model predictions, highlighting the utility of both the dataset and model in discovering unexplored C2 adsorbents.
CrySPR: A Python interface for implementation of crystal structure pre-relaxation and prediction using machine-learning interatomic potentials
Authors: Nong Wei , Zhu Ruiming , Hippalgaonkar Kedar
Published: August 2024

The functional properties of crystalline inorganic materials in a variety of applications including, but not limited to, catalysts, batteries, solar cells, electronics, fundamentally depend on their crystal structures. Discovery of novel materials could be transformative for these fields. In the past few decades, the computational science community has developed crystal structure prediction (CSP) methods with the goal to find the exact symmetry-constrained atomic arrangements in the periodic unit cell, which are globally and/or locally energetically favorable: finding the globally minimal or locally minimal crystal structure for a given chemical formula. The implementation of CSP typically involves an iteration procedure with at least two components: the sampling of the potential energy surface (PES) for generating raw/unrelaxed crystal structures, and the subsequent local energy minimization of generated structures. The latter part is typically carried out through computationally expensive density functional (DFT) calculations. A non-exhaustive but representative list of available CSP codes includes USPEX, CALYPSO, AIRSS, XtalOpt, IM2ODE; due to the nature of DFT calculations, this CSP process can be very time-consuming. Recent rapid advances of pre-trained machine-learning interatomic potentials (ML-IAPs) based on data from DFT calculations, such as, M3GNet, CHGNet and MACE (amongst others) have significantly accelerated the process of local energy minimization but have not thoroughly been tested on CSP tasks. The realization of local energy minimization using ML-IAPs, referred to as pre-relaxation when compared with using DFT calculations, plays a critical role in the CSP implementation. We present here, CrySPR, which stands for Crystal Structure Pre-Relaxation and PRediction, which is specifically designed to serve as a Python package that provides user-friendly application programming interfaces (APIs), functionalities and utilities for crystal structure generation, pre-relaxation of structures using ML-IAPs and structure prediction. The codes are open-source and have been released to the Python Package Index (PyPI).
مهارات التفكير الناقد لدى اعضاء برلمان كوردستان العراق
Authors: كريم بهار , عزيز عمر
Published: August 2024

هدف البحث الى التعرف على مستوى مهارات التفكير الناقد لدى أعضاء برلمان كوردستان العراق، ودلالة الفروق في ذلك تبعاً للمتغيرات الديمغرافية:( النوع الاجتماعي، العمر، القومية، التحصيل الدراسي، سنوات الخدمة في البرلمان) . واعتمد البحث على المنهج الوصفي في الدراسة، وتالف مجتمع البحث من (111) عضواً وعضوة في الدورة الخامسة للبرلمان. اما عينة البحث والتي تم اختيارها بصورة قصدية فتكونت من (95) عضواً وعضوة بواقع (67) ذكور و(28) اناث ، واستخدم الباحثان الصورة المختصرة من اختبار التفكير الناقد المعد من قبل واطسن – جليسر، وتمت معالجة البيانات إحصائياً باستخدام المتوسط الحسابي والانحراف المعياري والاختبار التائي لعينة واحدة ولعينتين مستقلتين وتحليل التباين الاحادي ومعادلة الفا كرونباخ. فاظهرت النتائج ان مستوى مهارات التفكير الناقد لدى أعضاء برلمان كوردستان العراق بشكل عام هو منخفض ، وتبين عدم وجود فروق دالة إحصائياً في مهارات التفكير الناقد تعزى لمتغيرات النوع الاجتماعي والعمر والقومية ومستوى التعليم وسنوات الخدمة في البرلمان. وفي ضوء النتائج التي أسفر عنها البحث تم تقديم جملة من التوصيات والمقترحات .
THE IMPACT OF ADVERSE GEOLOGICAL HAZARDS RISK ZONES ON CAR TRAVEL TIMES TO HOSPITALS: CASE STUDY OF THE KVEMO KARTLI REGION, GEORGIA
Authors:   Department of Geography, Faculty of Exact and Natural Sciences, Ivane Javakhishvili Tbilisi State University, ELIZBARASHVILI Mariam , KVIRKVELIA Bela ,   Department of Geography, Faculty of Exact and Natural Sciences, Ivane Javakhishvili Tbilisi State University, GAPRINDASHVILI George ,   Department of Geography, Faculty of Exact and Natural Sciences, Ivane Javakhishvili Tbilisi State University, DVALASHVILI Giorgi ,   Department of Geography, Faculty of Exact and Natural Sciences, Ivane Javakhishvili Tbilisi State University, ELIZBARASHVILI Shalva ,   Climatology and Agroclimatology Department, Institute of Hydrometeorology, Georgian Technical University, Georgia, KHUNTSELIA Tamar ,   Department of Geography, Faculty of Exact and Natural Sciences, Ivane Javakhishvili Tbilisi State University, ELIZBARASHVILI Elizbar ,   Climatology and Agroclimatology Department, Institute of Hydrometeorology, Georgian Technical University, Georgia, CHIKHRADZE Nino
Published: August 2024

Timely access to healthcare facilities is essential, as it can have a decisive impact on the outcome of any disease. Travel time is significantly affected by various factors, including extreme natural events. The purpose of the study was to consider the impact of adverse geological events on highways on the car travel time to the nearest hospital, and on this basis to identify served and underserved areas in terms of medical services in the Kvemo Kartli region. The findings revealed that only 5% of the Kvemo Kartli population resides in underserved areas i.e., outside the 45-minute car travel time to a hospital. However, this figure significantly increases to 38% when the impact of extreme geological events on the roads is considered, highlighting the region's vulnerability. These results can be instrumental in guiding efforts to improve healthcare availability in the region.
Kesalahan Berbahasa Pada Tataran Morfologi dalam Karya Tulis Ilmiah Siswa Kelas XII
Authors: Akmalita Diva , Markhamah Markhamah
Published: August 2024

Manusia memerlukan bahasa dalam kehidupan sehari-hari, baik bahasa lisan maupun bahasa tulis. Bahasa juga sangat berperan dalam dunia pendidikan. Tujuan penelitian ini adalah untuk mendeskripsikan kesalahan pada tataran morfologi dalam karya tulis ilmiah siswa kelas XII, menguraikan pembetulannya, dan menjelaskan penyebabnya. Penelitian ini menggunakan pendekatan kualitatif deskriptif. Data yang dikaji dalam penelitian ini berupa kalimat dalam karya tulis ilmiah siswa kelas XII yang mengandung kesalahan morfologis. Data bersumber dari lima dokumen karya tulis ilmiah siswa kelas XII di salah satu SMA di Kudus, Jawa Tengah. Setiap dokumen disusun oleh dua orang siswa, sehingga responden penelitian berjumlah 10 orang. Untuk mengumpulkan data, digunakan teknik baca, teknik catat, dan kuesioner/angket. Analisis data menggunakan teknik analisis isi. Hasil penelitian menunjukkan bahwa kesalahan morfologis pada karya tulis ilmiah siswa kelas XII meliputi: (1) kesalahan penulisan preposisi di dan ke, (2) kesalahan afiks, (3) kesalahan penulisan reduplikasi, dan (4) kesalahan pemajemukan. Penyebab terjadinya kesalahan morfologis pada karya tersebut, di antaranya: (1) siswa kurang membaca dan memperbanyak referensi, (2) kurangnya pembiasaan menulis, (3) kurangnya ketelitian siswa dalam menulis, dan (4) kurangnya arahan dan bimbingan guru.
PENGARUH KETERAMPILAN PRAKTIK DAN SELF-EFFICACY TERHADAP KESIAPAN KERJA SISWA KOMPETENSI KEAHLIAN TEKNIK INSTALASI TENAGA LISTRIK SMK NEGERI 2 SURABAYA
Authors: Muliasa Astridya Arini Cahya , Wrahatnolo Tri
Published: August 2024

ABSTRAK
Penelitian ini menggunakan pendekatan eksplanatori untuk melihat seberapa besar pengaruh keterampilan praktik dan self-efficacy terhadap kesiapan kerja siswa. Keterampilan praktik dan self-efficacy adalah variabel eksogen dan kesiapan kerja adalah variabel endogen. Sampel yang digunakan adalah 52 siswa dari kelas XII TITL SMK Negeri 2 Surabaya. Tes praktik dan survei digunakan dalam metode pengumpulan data keterampilan praktik, self-efficacy dan kesiapan kerja. Analisis data menggunakan PLS-SEM dengan software SmartPLS 3. Hasil penelitian menunjukkan bahwa keterampilan praktik berpengaruh positif tetapi tidak signifikan terhadap kesiapan kerja sebesar 0.139 dan P-value 0.130. Self-efficacy juga berpengaruh positif dan signifikan terhadap kesiapan kerja sebesar 0.940 dan P-value 0.000..                                                                                           
Kata Kunci: Keterampilan Praktik, Self-efficacy, Kesiapan Kerja
First record of Astathelohania contejeani (Henneguy, 1892) in the narrow-clawed crayfish Pontastacus leptodactylus (Eschscholtz, 1823) from Belarus
Authors: Śliwińska Karolina , Skuratovich Elena , Alekhnovich Anatoly
Published: August 2024

Porcelain disease, caused by the parasite Astathelohania contejeani, is a fatal disease for freshwater crayfish. Previously published data provide information on the occurrence of A. contejeani in various crayfish species. However, its prevalence in host populations remains largely undetermined. This issue is relevant to the narrow-clawed crayfish Pontastacus leptodactylus, a species of high commercial value in Eastern Europe. A single published report addressed a potential microsporidia infection in P. leptodactylus, but without specific data on geographical location and prevalence. We present the first detailed information on the prevalence of A. contejeani in the P. leptodactylus population from Lake Losvido, including an assessment of the infection rate through both visual and molecular assessment. Astathelohania contejeani was observed in 1.56% of 128 crayfish examined visually. Of the 37 asymptomatic crayfish samples analyzed, 29.7% were found to be carriers. This finding suggests that parasitism of A. contejeani occurs frequently in the P. leptodactylus population in Lake Losvido prior to the manifestation of observable disease symptoms.
Integrated multi-trophic aquaculture of the European flat oyster (Ostrea edulis Linnaeus, 1758): A case study from Boka Kotorska Bay (Montenegro)
Authors: Nikolić Slađana , Mandić Milica , Pešić Vladimir , Ikica Zdravko , Peraš Ines
Published: August 2024

Although integrated multi-trophic aquaculture (IMTA) is recognized as a strategy to control and minimize the impact of fish farming on the marine environment, there are still many unknowns when it comes to this type of farming. This paper presents the results of research on the growth of European flat oysters in IMTA and monoculture systems. Growth was monitored at three different sites: near fish cages, 100 m from fish cages, and in a monoculture system, during an 18-month experiment. The highest mortality occurred at the site near the fish cages. At the end of the experiment, all monitored individuals reach commercial size, except for four individuals at the site near the fish cages. There were statistically significant differences in oyster growth with respect to site and period. At the site near the fish cages, oyster growth was significantly lower compared to the growth at the two other sites. The most intense growth of oysters occurred during the spring and early summer period. Our results indicate that the production cycle of oysters in integrated aquaculture and monoculture is quite similar and that sites directly adjacent to fish cages should be avoided for oyster farming.
Toxicity assessment of advanced biological wastewater treatment plant effluent by integrated biomarker response in zebra mussels (Dreissena polymorpha)
Authors: Serdar Osman , Ketenalp Zozan , Yildirim Nuran Cikcikoglu
Published: August 2024

In this study, zebra mussels (Dreissena polymorpha) were exposed to advanced biological wastewater treatment plant effluent (ABWTPE) for 96 h. At the end of the 96th hour, antioxidant parameters such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione S-transferase (GST), malondialdehyde (MDA) and glutathione (GSH) were examined. The objective of the study was to identify biomarkers that are useful for assessing the potential toxic effects of ABWTPE in freshwater environments. We observed an increase in GPX, SOD activity and MDA levels, and a decrease in CAT, GST activity and GSH levels. The results obtained in our study showed that the measured biochemical parameters (GSH, MDA, SOD, CAT, GPX and GST) are useful biomarkers in determining the possible toxicity of ABWTPE in aquatic environments.
YÜKSƏK DƏRƏCƏLİ İDMANÇILARIN LABORATORİYA ŞƏRAİTİNDƏ MƏŞQ VƏ YARIŞ DÖVRÜNDƏ FİZİOLOJİ MONİTORİNQİ
Authors: K.V. Mukhtarova  , M.T. Abbasova  , G.D. Yusifov  , Sh.N. Niftaliyeva
Published: August 2024

Məqalədə yüksək ixtisaslı idmançıların fiziki işə uyğunlaşması prosesində klinik və laboratoriya markerlərinin dəyişkənliyini xarakterizə edən məlumatlar təqdim olunur. Müasir dövrdə idmançıların səhətində baş verən problemlərdən sonra idmançılarla aparılan testlər vacib sayılır. Müxtəlif sistemlərin vəziyyətini xarakterizə edən göstəricilərin fizioloji dəyişkənliyini təyin edən biokimyəvi və hematoloji test nəticələri haqqında məlumatlar verilir. Əldə edilən məlumatlar müxtəlif səviyyəli xüsusi hazırlıq səviyyələrində idmançılar üçün məşq yüklərini yerinə yetirərkən maddələr mübadiləsinin xüsusiyyətlərini nəzərə almağa imkan verir.
Adversity in childhood as a risk and vulnerability factor for intimate partner violence
Authors: Ruiz-Fuentes Olinda Dulcemaría , Molina Coloma Verónica Alexandra
Published: August 2024

Adverse childhood experiences (ACE) constitute a complex and devastating phenomenon that has lasting consequences on a person's life. These experiences include, but are not limited to, physical, emotional, or sexual abuse, neglect, abandonment, and exposure to domestic violence. Numerous studies have shown that ACE not only affect the emotional and psychological development of children, but also have profound and lasting implications in adult life, such as the impact on emotional regulation and the formation of healthy relationships, including couple relationships. Research suggests that people who have experienced childhood adversity are at greater risk of finding themselves in violent relationships, either as victims or perpetrators. This connection may be due to a variety of factors, including internalization of abusive behaviour patterns, difficulties in emotional regulation, and low self-esteem. Meanwhile, the objective of this study is to carry out a theoretical review of what has been studied in this regard with the aim of understanding how adverse experiences in childhood can predispose people to intimate partner violence. This knowledge is not only vital for the development of effective prevention strategies, but also for the design of therapeutic interventions that help break the cycle of violence.
Quality of life assessment of adolescent secondary school students from Potosí
Authors: Galán-Cuevas Sergio , López-Miramón Yireh Anahi , Pineda-Sánchez Jose Esael
Published: August 2024

Quality of Life (QOL) and Health-Related Quality of Life (HRQOL) are essential concepts for understanding the well-being of individuals, particularly during adolescence, which is a crucial transitional stage in the lives of human beings. The assessment of QOL supports us in gaining a comprehensive understanding of well-being and development at various stages of life. Assessing QOL in adolescents allows researchers and health professionals to understand the specific dynamics of this population. Method. The present study assessed QOL in adolescents from technical high schools in vulnerable areas of San Luis Potosí. The Kidscreen-52 scale (KS-52) was used to probe physical, emotional and social aspects, as well as risk factors. A total of 797 students (50% male, 50% female) between 11 and 15 years of age from two technical high schools participated in the study. Of the sample, 35.94% were first year students, 38.39% were second year students and 26.47% were third year students. Results. Statistical differences were found for internal factors (t=5.87; gl 795; p < .001) between males and females, with lower scores in the latter. Likewise, greater vulnerability was observed in the first and third grades (F= 3.076; p = 0.047). In both subsamples, the relevance of socioeconomic status and parental and family relationship as external factors predominates, and physical and psychological well-being, self-perception and autonomy as internal factors. Conclusions. The findings of the present work support the importance of approaching adolescent QOL from a comprehensive perspective, considering both internal and external factors that influence their overall well-being.
Nature-Based Solutions in Urban Landscapes: Determinants Influencing Willingness to Participate in Composting in Metropolitan Jakarta, Indonesia
Authors: Mulyana Rachmat , Suryawan I Wayan Koko , Ulhasanah Nova , Septiariva Iva Yenis , Prayogo Wisnu , Suhardono Sapta , Sari Mega Mutiara , Arifianingsih Nur Novilina , Buana Dwinto Martri Aji
Published: August 2024

Amidst the rapid urbanization of Jakarta, the adoption of Nature-based Solutions (NbS) like composting offers a sustainable pathway for waste management and environmental rejuvenation. This research endeavors to discern the critical factors impacting the willingness of Jakarta's metropolitan populace to participate in composting activities. The study identified key determinants through a comprehensive analysis, including the availability of composting facilities, the expertise of trained cadres, the adoption of advanced composting technologies, and routine field monitoring. Furthermore, demographic nuances, specifically marital status, and age, surfaced as influential parameters. Singles and the younger age bracket (20-29 years) exhibited distinct attitudes towards composting, hinting at underlying generational and lifestyle-based disparities. The findings provide a foundation for tailoring policies and interventions that cater to Jakarta's unique urban fabric, promoting a more inclusive and influential composting culture.
Assessing Urban Flooding and Drainage System Performance in Urban Area: A Mononobe Equation and Manning Formula Approach
Authors: Rahma Sukma Laksita , Sunarsih  , Mussadun
Published: August 2024

Climate change causes erratic rainfall and often results in flooding of urban areas. Floods are hydrometeorological disasters that occur in various regions of Indonesia. Flood vulnerability in urban areas has increased over the past 30 years. Kauman Village is included in the Asri water catchment area, which has an Asri primary channel downstream of the urban area of Nganjuk District. However, from 2019 to 2022, the urban area of Nganjuk District, including Kauman Village, was affected by flooding. Urban floods inundated office areas, schools, housing, and public facilities such as the Nganjuk District General Hospital. The factor indicated as the cause of flooding is the clogging of the drainage channel with rubbish. Therefore, field research and mathematical calculations were conducted to evaluate the discharge capacity of drainage channels in the village. Based on the research, it was found that the existing drainage channel discharge in the research area could not accommodate the planned discharge for the 10-year return period. In addition, there are 33 channels that are unable to accommodate the planned discharge because the channeldimensions are too small, some channels are slightly damaged, sedimentation occurs, and they are blocked by rubbish. Drainage channels that do not function optimally affect urban flooding. Therefore, several efforts have been made to reduce the risk of flooding by changing the dimensions of drainage channels, normalizing drainage channels, and getting used to maintain drainage channels and not throwing rubbish in drainage channels.
Assessing Urban Level Changes Using GIS and Statistical Analysis in the Kedungsepur Metropolitan, Indonesia
Authors: Indrayati Ariyani , Rijanta  , Muta'ali Luthfi , Rachmawati Rini
Published: August 2024

From 2010 to 2020, the Kedungsepur Metropolitan Corridor experienced spatial transformations, converting agricultural areas into built-up areas. This study seeks to identify new insights by examining the correlation between socioeconomic facilities and built-up areas, typically analyzed separately. Satellite imagery interpretation was used to determine the proportion of built-up areas, apply the K-Means Cluster method for the urban level, and conduct statistical analysis using the chisquare test. The findings reveal that the Semarang—Ungaran—Salatiga Corridor has the greatest built-up areas. The average change in built-up area within the Kedungsepur Metropolitan Corridor from 2010 to 2020 was 3.25%. Additionally, the Central Semarang Subdistrict had the highest level of socioeconomic facilities. However, the Chi-Square test results indicated differences between the observed and expected frequencies of built-up area percentages in each subdistrict for both 2010 and 2020. Surprisingly, no correlation was found between urban-level changes related to built-up areas and socioeconomic facilities. These results suggest that urban changes in the primary city are relatively stagnant, while more intensive development occurs in secondary cities withinKedungsepur. The dominant driving factor for urban transformation is the change in built-up areas,which indicates the intensified growth of secondary cities.
The Display Behavior of Sub-Adult Greater Bird-of-Paradise (Paradisaea apoda): A Learning Process from an Adult?
Authors: Pramunandya Raka Aditya , Mardiastuti Ani , Mulyani Yeni , Chandra Vinoba
Published: August 2024

The Greater Bird-of-Paradise (Paradisaea apoda) is a bird that performs a courtship display (lekking) to attract females during the mating season. The objective of this study was to examine the display behavior of adult and sub-adult males on lek trees as a learning process by a sub-adult and identify the lek trees. The research was conducted in the Tunas Timber Lestari Ltd. Production Forest in central mainland Papua, in a non-breeding season. After a lek tree was found, a video recording was conducted. Analysis was performed from the video. The lek tree was an emergent species with a dense canopy. An adult male was observed to perform a dance display in front of sub-adult males, even in the absence of females. When adult males performed display, the sub-adult were observed the adult males in an upside-down position. The sub-adult also danced, but not as complete as the adult, suggesting that there was a learning process by the sub-adult. This study revealed that the sub-adult/young males of the bird-of-paradise has the ability to dance inherit from their fathers, and then perfect the dance through practice and watching adults. The lek tree surely need to be protected for the survival for this species.
The Movement to Maintain Food Security Through Technological Advancements and Local Diversification: Ministry of Agriculture Republic of Indonesia
Authors: Herlina Nia , Wahyuni Herpita , Winahyu Fauziyya Puji , Anwar Khairul , Heliana
Published: August 2024

This study aims to determine the food security movement using a qualitative descriptive research method assisted by NVivo 12 Plus software from the Twitter account data source of the Ministry of Agriculture Republic of Indonesia, supported by previous research. Data coding was obtained from Twitter, social media, and news data, which supported the findings using a crosstab query feature. The analysis found that the government's strategy for maintaining food security was to increase production capacity, diversify local food, strengthen food reserves and logistics systems, and develop modern agriculture. They increased food production by intensifying 85,456 hectares of swamp land and maximizing 85,456 hectares of land. Diversifying local food by massively utilizing local food as an alternative food supply and strengthening food reserves and logistics systems by supporting food reserves that can be used to help other areas affected by disasters as a form of social care, and developing modern agriculture with Smart Farming Developing technology-based clever farming methods, including Agri Drone Sprayer liquid, Surveillance Drones (drones for land mapping), Soil and Weather Sensors, as well as the development of food safety applied to households. Scale with vertical hydroponic growing system training.
Estimating the Water Balance of Irrigated Rice Fields in Dry Season Makurdi, Nigeria
Authors: Ukpoju Augustine , Oue Hiroki
Published: August 2024

The water balance (WB) of three irrigated and isolated rice fields (1, 2, and 3) was examined during the dry season of rice cultivation in Makurdi from April 5 to May 6, 2023. Rice is mostly cultivated in the wet season, while dry season rice cultivation is limited by high irrigation costs, funding, and technical knowledge amidst vast water resources around the floodplains. Limited or no research estimates the water balance of a rice field in dry season Makurdi. WB took account of water inputs, outputs, and changes in soil water content (ΔW) in each water balance period. In Field 1, the WB showed a negative ΔW (–42.94 mm), which suggests that adequate water inputs are required to balance the water lost (outputs). The WB showed a positive ΔW of (89.36 mm and 464.75 mm) in Fields 2 and 3, suggesting that the water inputs be minimized to avoid wastage. The total irrigation in Fields 1, 2, and 3 was 499.28 mm, 1,186.95 mm, and 1,400.27 mm, respectively. The irrigation efficiency in Fields 1, 2, and 3 was 39.8%, 29.9%, and 20.9% respectively. The result indicates that Field 1’s rice cultivation can be improved by providing adequate irrigation and enhancing the soil water retention capacity, while proper irrigation scheduling can improve Fields 2 and 3 rice productivity.
Optimalisasi Manajemen Dana Bos dalam Meningkatkan Mutu Pendidikan Islam
Authors: Said Majid , Sulhan Ahmad , Hakim Lukman
Published: August 2024

Lembaga pendidikan Islam di Indonesia menghadapi permasalahan yang kompleks jika dibandingkan dengan lembaga pendidikan umum, dalam hal peningkatan mutu pendidikan.  Madrasah sebagai salah satu bentuk lembaga formal pendidikan Islam, menghadapi berbagai persoalan yang berkaitan dengan peningkatan mutu, salah satunya adalah dana yang minim. Menyikapi kondisi ini, pemerintah melalui program dana BOS berusaha membantu lembaga pendidikan untuk meningkatkan mutu. Kaitannya dengan fenomena tersebut, fokus kajian penelitian ini adalah optimalisasi manajemen dana BOS yang dilakukan oleh MA Plus Munirul Arifin NW Praya dalam rangka meningkatkan mutu pendidikan Islam. Penelitian menggunakan metode kualitatif dengan pendekatan studi kasus. Hasil penelitian ini menunjukkan bahwa optimalisasi manajemen yang dilakukan oleh MA Plus Munirul Arifin NW Praya dimulai dari penyususnan anggaran, pembukuan, pemeriksaan, pengalokasian, dan evaluasi. Optimalisasi manajemen dana BOS yang dilakukan, dapat meningkatkan nilai tambah dari komponen-komponen standar mutu lembaga pendidikan. Sehingga manajamen yang dilakukan oleh MA Plus Munirul Arifin NW Praya dapat menjadi role model bagi lembaga-lembaga pendidikan Islam lain, demi meningkatkan mutu pendidikan Islam.
O Combate ao Analfabetismo na EJA: Uma Percepção Freiriana
Authors: Vale Rodrigo Magno dos Santos , Rocha José Cláudio
Published: August 2024

O presente artigo tem como finalidade refletir sobre a importância da Educação de Jovens e Adultos (EJA) na perspectiva freiriana. Dentro desse escopo, abordaremos as contribuições de Paulo Freire para a construção de novos olhares para a EJA, principalmente no combate ao analfabetismo de jovens e adultos. A metodologia utilizada para dialogar de maneira mais acadêmica é uma revisão bibliográfica dos livros de Paulo Freire e outros autores que corroboram para o maior entendimento sobre o tema. Dentro dessa proposta, criou-se um problema questão que norteará toda a discursão do artigo, sendo ela: Como o Método de Freire impulsionou um novo olhar o combate ao analfabetismo na Educação de Jovens e Adultos? Partindo dessa problemática, esse artigo dialogará com questões voltadas ao desenvolvimento educacional na EJA, princípios norteadores para o processo de alfabetização e a trajetória do método freiriano na Educação de Jovens e Adultos.
Extensão ou Comunicação? A Reificação do Ensino versus suas Possibilidades
Authors: FINELLI LEONARDO AUGUSTO COUTO , Prates Admilson Eustáquio , Oliveira Pedro Alexandre Fróis de
Published: August 2024

Paulo Freire durante seu exílio estudou e educou a partir de um olhar de amor. Em suas experiências escreveu o ensaio “Comunicación o Extensión?”, a partir de sua análise das dificuldades do técnico agrônomo “em educar” o camponês ao uso das técnicas científicas em sua prática extensionista. A partir dessa obra, que só foi publicada no Brasil quase 15 anos após seu original, tomamos como objetivo deste artigo refletir sobre a como pode se dar a educação nos mais diversos contextos. Tal se justifica pela atualidade da obra freiriana influenciando educadores no Brasil e fora dele. Metodologicamente, consideramos uma pesquisa bibliográfica, que partiu da obra de referência. Essa foi complementada com outras obras freirianas, assim como por fontes atualizadas de modo a complementar a discussão. Os resultados indicaram que o processo de educar não pode se dar a partir da imposição do conhecimento novo. Reconhecemos a educação libertária, que se dá a partir do diálogo para o avanço do ato de ensinar. Concluímos que o conhecimento da sistematização da obra freiriana apresenta reescritas sobre como a dialogicidade é a via de produção da educação. Nesse sentido, a “Extensão” deve se dar como “Comunicação”, e a partir dessa. De uma forma dialógica, que favoreça a interação, e a possibilidade de escolha de mudança de cultura, e de práticas, e não pela imposição de um saber externo que não se reconhece, e, consequentemente, não se pratica.
FORMAÇÃO CONTINUADA: RELAÇÕES COM A ALFABETIZAÇÃO E LETRAMENTO
Authors: Silva Marli da
Published: August 2024

RESUMO
O objetivo geral desse artigo é analisar as implicações que envolvem a formação dos professores em relação a alfabetização, dada a importância da competência didática em leitura e escrita, dos professores, com suas particularidades nos anos iniciais. Segue-se uma revisão bibliográfica, descritiva e qualitativa, que permitiu sistematizar estudos preliminares realizados por reconhecidos investigadores sobre o tema; também às experiências de capacitação de docentes conforme o nível educacional de formação, bem como às investigações empíricas dos autores, na etapa exploratória. O resultado indicou a existência de uma população docente com baixo nível de alfabetização, cujo fortalecimento é importante para influenciar o desenvolvimento de competências desde cedo. Refletiu-se sobre a formação dos professores como garantia para que os alunos dominem diversas estratégias para garantir uma mediação eficaz no processo de alfabetização. Ressalta-se o grande valor que possuem os docentes do 2º ano do Ensino Fundamental ao levarem em consideração as particularidades deste nível ao trabalharem o processo de alfabetização, leitura e escrita.

Palavras-chave: Alfabetização. Leitura. Escrita. Formação Continuada.
ESTRATÉGIAS DIDÁTICAS PARA O ENSINO DE MATEMÁTICA POR MEIO DAS TECNOLOGIAS
Authors: Melo José Eronildo de
Published: August 2024

RESUMO

O objetivo desta pesquisa foi analisar estratégia didática para aprendizagem de Matemática para ensinar álgebra. O tipo de estudo desenvolvido foi descritivo, com métodos teóricos e empíricos que permitem melhor analisar o problema e auxiliar pesquisadores a reunirem mais informações sobre o objeto de estudo. Entre os principais resultados obtidos está a concepção e implementação da própria estratégia de ensino, que constitui um contributo prático essencial para o método de estudo-aprendizado da Matemática. Com a utilização das TIC e das atividades desenvolvidas, consegue-se uma melhor preparação dos alunos. Nos resultados alcançados foi detectado que o uso das TIC em contextos educativos melhora significativamente a motivação nos alunos e ao mesmo tempo promove neles a autonomia, também foi demonstrado que conseguem integrar-se de forma excelente no aprendizado da álgebra com auxílio dos recursos digitais. Finalmente contatou-se, que o ensino dinâmico é um aspecto abordado nas pesquisas e pode ser traduzido em um chamado muito importante de atenção aos professores para inovarem e removerem velhas formas de transmitir conhecimento, nesse caso na disciplina de matemática por meio das tecnologias.

Palavras-chave: Estratégia Didática. Álgebra. Tecnologias. Ensino de Matemática. Processos Educacionais.