bluuebunny/crossref_metadata_2025 huggingface dataset:
Integration between genetic and chemical control on the progress of Asian soybean rust and yield
Authors: Sacon Deivid , Netto Aline , Fochesatto Michele , Stefanski Francine Spitza , Gallina Alessandra , Milanesi Paola Mendes , Borges Leandro Luiz
Published: September 2020

ABSTRACT The objective of this study was to evaluate the genetic control integrated to the chemical control of Asian soybean rust (ASR) and the effects of these measures on crop yield. The experiment was conducted in Erechim, Rio Grande do Sul State, Brazil, in 2016/17 and 2017/18 crop years, under a randomized block design, in a subdivided plot scheme (cultivars in the plots and fungicides in the subplots), with four replicates. The following cultivars were used: BMX Vanguarda (without ASR tolerance); TMG 7062; TMG 7262, and TMG 7161, tolerant to ASR (Inox™ Technology cultivars). The fungicides used were: T1) control (without application of fungicides); T2) azoxystrobin + benzovindiflupyr; T3) difenoconazole + cyproconazole; T4) trifloxystrobin + prothioconazole, and T5) epoxiconazole + fluxapyroxad + pyraclostrobin. Four fungicide applications were carried out at the V6, R1, R5.1 and R6 stages. During the experiment, for the calculation of the area under disease progress curve (AUDPC), disease severity was assessed at 7-day intervals in a random sample of 10 trifolia per plot. After harvest, yield components were determined: number of grains per plant, thousand grain weight (g), and yield (kg ha-1). In 2017/18 crop year, the fungicide difenoconazole + cyproconazole was not efficient for ASR control. The soybean cultivars TMG 7062, TMG 7161 and TMG 7261 delayed the disease progression; however, only TMG 7161 presented tolerance in the presence of the inoculum in 2016/17 and 2017/18 crop years. The association between chemical and genetic control is shown to be efficient for ASR control.
Inserção social: princípio e compromisso na experiência da Pós-graduação em Serviço Social na Pontifícia Universidade Católica de Goiás
Authors: Neves Denise Carmen de Andrade , Silva Maísa Miralva da , Tavares Rosana Carneiro
Published: September 2020

Resumo: Este artigo apresenta o mestrado em Serviço Social da PUC Goiás, considerando o acompanhamento dos egressos e objetiva explicitar sua inserção social na realidade local e regional. Destaca seu caráter interdisciplinar e aponta que os egressos estão inseridos em instituições de ensino superior e em atividades relacionadas ao controle social. Essa inserção se materializa, ainda, na qualificação desses profissionais, com vistas à ampliação do acesso a direitos da população goiana e brasileira.
Esforços da Pós-graduação em políticas públicas e desenvolvimento local para a Interiorização
Authors: Dalbello-Araujo Maristela , Andrade Janice Gusmão F. , Ramos-Silva Valmin
Published: September 2020

Resumo: As contribuições da pesquisa científica à sociedade podem ser medidas por indicadores e a inserção social dos programas de pós-graduação. Neste artigo discutimos as particularidades do impacto social do Programa de Pós-Graduação em Políticas Públicas e Desenvolvimento Local da Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória, assinalando seu importante papel na difusão dos conhecimentos, especialmente na área das políticas de saúde para o estado do Espírito Santo.
Tendências do estado nutricional de crianças no período de 2008 a 2015: dados do Sistema de Vigilância Alimentar e Nutricional (Sisvan)
Authors: Moreira Naiara Ferraz , Soares Camilla de Almeida , Junqueira Túlio da Silva , Martins Rita de Cassia Bertolo
Published: September 2020

Resumo Introdução O Sistema de Vigilância Alimentar e Nutricional (Sisvan) é de abrangência nacional e essencial para monitorar o crescimento e o desenvolvimento da criança na Atenção Primária à Saúde. Objetivo Descrever a cobertura e a tendência temporal do estado nutricional de crianças de 5 a 9 anos cadastradas no Sisvan entre 2008 e 2015. Método Análise de regressão linear simples para verificar a tendência temporal do número de registros, da cobertura e da classificação do estado nutricional de crianças de 5 a 9 anos em quatro territórios (município de Dourados, estado do Mato Grosso do Sul, região Centro-Oeste e Brasil). Resultados Verificou-se tendência de aumento no número de registros, exceto para Dourados, que apresentou padrão irregular (p = 0,123). Magreza e eutrofia apresentaram tendências de queda, enquanto sobrepeso e obesidade aumentaram no período e nos territórios avaliados, com exceção de Dourados, que não apresentou resultados significativos para eutrofia (p = 0,145) e obesidade (p = 0,318). Conclusão O número de registros e, consequentemente, a cobertura do Sisvan aumentaram de forma significativa em três dos quatro territórios avaliados. Os resultados referentes ao estado nutricional retratam e fortalecem o processo de transição nutricional vivenciado no país.
AN ANALYSIS OF THE INFLUENCE OF THE CONSPICUOUS CONSUMPTION OF FAST FASHION ON IDENTITY CONSTRUCTION ON INSTAGRAM
Authors: DANTAS BRUNA L. L. , ABREU NELSIO R.
Published: September 2020

ABSTRACT Purpose: The objective of this investigation is to analyze the influence of the conspicuous consumption of fast fashion products on Instagram on the identity construction process of female fashion consumers. Originality/value: Filling a gap in the literature relating to conspicuous consumption and identity construction, this investigation analyzes the consumption dynamics, investigating relevant phenomena on a current and relevant online social network: Instagram; and explaining, in an analysis by categories, the continued dissatisfaction of consumers with the goods that drive and determine the dynamics of fast fashion consumption. Design/methodology/approach: The methodology was qualitative, triangulating data from participant observation, interviews, and online focus groups. Eleven women were interviewed, and three focus group sessions were conducted, with a total of sixteen participants. The data were analyzed through content analysis with categories before and subcategories that emerged afterwards. Findings: The findings show the conspicuous consumption of fast fashion products on Instagram as creators of sense, self-concept, and self-image, following and demonstrating the lifestyle of consumers. The satisfaction resulting from people’s approval, the goods used for compliance in social groups, and the continued dissatisfaction with their possession are observed, which drives fast fashion consumption. The constructed identities are presented as contextual, fluid, and fragmented.
O TAYLORISMO SOB CONTROLE: O LUGAR DAS NOVAS E VELHAS TECNOLOGIAS NA ORDEM INDUSTRIAL
Authors: SILVA LUCAS FRAZÃO , MONTAGNER MIGUEL , ROSELINO JOSÉ EDUARDO
Published: September 2020

RESUMO Este artigo discute criticamente o possível esgotamento histórico do taylorismo. Pretende apontar que, passados praticamente 100 anos desde sua difusão inicial, as formas de controle propostas pela administração científica foram aprimoradas, modernizadas e transformadas a tal ponto que parecem superadas historicamente. No entanto, a rápida difusão de sistemas eletrônicos de segurança no mundo corporativo representa uma evidência concreta da perenidade das formas tayloristas de controle que, transmutadas, assumem novas características no atual paradigma tecno-produtivo.
The effects of favipiravir on hematological parameters of covıd-19 patients
Authors: Yaylaci Selçuk , Dheir Hamad , Şenocak Didar , Genc Ahmed Bilal , Kocayigit Havva , Çekiç Deniz , Varım Ceyhun , Aydın Abdülkadir , Koroglu Mehmet , Karabay Oğuz
Published: September 2020

SUMMARY INTRODUCTION This study aims to evaluate changes in hematological parameters after the follow-up of patients who received treatment with favipiravir due to COVID-19 infections. METHODS Sixty-two cases receiving favipiravir treatment for at least five days due to COVID-19 infection were evaluated retrospectively. Parameters including age, gender, nasopharyngeal swab positivity, and chronic diseases were analyzed. Hematologic parameters were analyzed before and after the treatment. RESULTS The mean age of the patients receiving treatment with favipiravir was 63.7±12.3 years. Nasopharyngeal swab positivity was detected in 67.7%. The most common comorbid conditions detected in patients were hypertension in 25 cases (40.3%) and diabetes in 16 cases (25.8%). In the statistical analysis of the hematological parameters before and after treatment with favipiravir, WBC, PT-PTT-INR levels were found to be unaffected; the mean RBC was found to have decreased from 4.33 ± 0.58 M/uL to 4.16 ± 0.54 M/uL (p:0.003); the median hemoglobin level was found to have decreased from 12.3 g/dl to 11.9 g/dl (p:0.041); the hematocrit level decreased from 38.1% ± 4.8 to 36.9% ± 4.2 (p:0.026); the median neutrophil count decreased from 4.57 K/uL to 3.85 K/uL (p:0.001); the mean lymphocyte count increased from 1.22 ± 0.53 K/uL to 1.84 ± 1.19 K/uL (p:0.000); and the mean platelet count increased from 244.1 ± 85.1 K/uL to 281.9 ± 103.3 K/uL (p:0.005). CONCLUSION We concluded that the pathological effect of treatment with favipiravir on the hematologic system was the suppression in the erythrocyte series, and there were no adverse effects in other hematologic parameters.
FREQUÊNCIA DE ANTICORPOS E FATORES DE RISCO ASSOCIADOS À LEUCOSE ENZOÓTICA BOVINA EM REBANHOS DA BACIA LEITEIRA DO ESTADO DO MARANHÃO
Authors: Santos H.P. , Pereira H.M. , Nascimento S.A. , Coutinho L.C.A. , Teixeira W.C. , Arruda R.C.N. , Bezerra N.P.C , Bezerra D.C. , Castro R.S.
Published: September 2020

RESUMO Este trabalho teve como objetivo determinar a frequência e os possíveis fatores de risco as-sociados à ocorrência da Leucose Enzoótica Bovina (LEB) na bacia leiteira do Estado do Maranhão. Amostras de soro de 920 animais da raça girolanda foram submetidas à técnica de imunodifusão em gel de ágar. O estudo foi realizado em 92 propriedades leiteiras, pertencentes a 23 municípios localizados nas regionais de Açailândia, Bacabal, Ilha de São Luís, Imperatriz e Pedreiras. Em cada propriedade avaliada, aplicou-se questionário epidemiológico para investigar os fatores de risco que poderiam estar associados a esta infecção. Das 920 amostras de soro analisadas, 53,80% foram reagentes. Nas regionais obtiveram-se frequências de 63,50%, 61,87%, 60,62%, 41,18% e 30,83%, para Bacabal, Ilha de São Luís, Pedreiras, Imperatriz e Açailândia, respectivamente. Nos 23 municípios amostrados foram encontrados animais reagentes, com detecção de bovinos sorologicamente positivos em 98,91% das propriedades. Dentre os fatores de risco avaliados, uso repetido da mesma agulha para colheita de sangue ou vacinação, uso repetido da mesma luva obstétrica, estabulação dos animais e ausência de assistência veterinária apresentaram significância estatística (P < 0,05) associada à LEB. Os resultados do estudo indicam que a frequência de anticorpos para a Leucose Enzoótica Bovina foi elevada na bacia leiteira do Estado do Maranhão e que os fatores relacionados ao manejo estiveram associados ao risco de infecção nos bovinos.
ANTICORPOS IgG ANTI-TOXOPLASMA GONDII EM SUÍNOS ABATIDOS EM MATADOUROS DA REGIÃO METROPOLITANA DO RECIFE, PERNAMBUCO, BRASIL
Authors: Samico Fernandes E.F.T. , Simões S.G. , Faria E.B. , Samico Fernandes M.F.T. , Pinheiro Júnior J.W. , Mota R.A.
Published: September 2020

RESUMO Objetivou-se avaliar a frequência da infecção por Toxoplasma gondii em suínos abatidos para o consumo humano em dois matadouros na Região Metropolitana do Recife, Pernambuco com inspeção Sanitária Estadual. A pesquisa de anticorpos foi realizada por meio da reação de Imunofluorescência indireta, adotando-se o ponto de corte 1:64. Foram analisados 327 animais provenientes de seis cidades, Abreu e Lima, Igarassu e Paulista, Carpina, Paudalho e Tracunhaém. Observou-se frequência de 9,78% de soros positivos, com diluições iguais ou superiores a 1: 64. Os resultados obtidos alertam sobre os riscos de infecção por T. gondii pela ingestão da carne suína crua ou mal cozida, pois é provável que os suínos soropositivos abriguem cistos teciduais, ressaltando a importância de um manejo de criação adequado, visando a diminuição do risco de infecção nesta espécie.
HEMOPARASITAS EM JACARÉ AÇU E JACARÉ TINGA CAPTURADOS NA APA MEANDROS DO RIO ARAGUAIA
Authors: Santos A.L.Q , Pereira H.C. , Silva J.M.M , Hirano L.Q.L.
Published: September 2020

RESUMO As infecções são comuns tanto em populações silvestres como nas de cativeiro e a ocorrência de doenças está entre as maiores ameaças à diversidade biológica que podem resultar da atividade humana. A maioria das espécies de vida livre enfrenta problemas que aceleram a sua trajetória em direção a uma possível extinção. Haja vista a importância da pesquisa de parasitas em animais silvestres como uma ferramenta para o estudo sanitário de uma população e da qualidade do ambiente, objetivou-se investigar a presença e frequência de hemoparasitas em jacaré açu (Melanosuchus niger) e jacaré tinga (Caiman crocodilus) de vida livre, na Área de Proteção Ambiental Meandros do Rio Araguaia, Goiás, Brasil. Foram avaliados esfregaços sanguíneos de 65 espécimes, 26 M. niger e 39 C. crocodilus, corados com Wright. As coletas ocorreram no período de outubro de 2006 a junho de 2007. Os eritrócitos foram analisados em 20 campos por lâmina. Verificou-se a presença de hemoparasitas intraeritrocitários em 46 (70,76%) dos animais analisados, os quais foram reconhecidos como pertencentes ao gênero Coccidia e da família Haemogregarinidae, revelando um alto índice de hemoparasitose em crocodilianos desta região.
INFLUÊNCIA DE DIFERENTES pH E CONCENTRAÇÕES DE SUBSTRATO CUTICULAR E NÃO-CUTICULAR NA ATIVIDADE PROTEOLÍTICA DE ISOLADOS DE METARHIZIUM ANISOPLIAE
Authors: Costa P.M.O. , Tiago P.V. , Nascimento T.L.
Published: September 2020

RESUMO A produção de proteases por Metarhizium anisopliae (Metsch.) Sorokin é considerada um importante fator de virulência, pois são fundamentais no processo de penetração através da cutícula do inseto. O objetivo do trabalho foi verificar a influência de diferentes pH e concentrações dos substratos caseína e cutícula de Mahanarva fimbriolata (Stål) (Hemiptera: Cercopidae) na atividade proteolítica de isolados de M. anisopliae. Foi utilizado meio mínimo (MM) sólido, exceto fonte de carbono, acrescido de caseína e cutícula de M. fimbriolata, ambos nas concentrações de 1%, 2%, 3% e 4%. Para verificar a influência do pH na atividade proteolítica e possível mudança de pH no meio, os meios citados acima foram preparados na concentração em que foi observada a maior atividade proteolítica, com pH inicial 5, 6, 7, 8, 9 e 10 e contendo indicador de pH. A atividade enzimática foi determinada através do índice de relação enzimática (IRE). Foi observado que os isolados de M. anisopliae apresentaram concentrações ótimas distintas para cada substrato, sendo 1% para a caseína e 2% para a cutícula de M. fimbriolata. Quanto ao pH, foram verificadas maiores atividades proteolíticas em caseína nos pH 8 e 9 e em cutícula de M. fimbriolata nos pH 6, 7 e 8. Foi verificado, a partir do quinto dia de crescimento dos isolados, uma mudança de coloração no meio caseína 1% de pH inicial 6 e 7 para um pH final 8. Portanto, a concentração dos substratos estudados e o pH do meio influenciaram na atividade proteolítica.
Qualitative and quantitative analysis of Mercury ions on the surface of amalgam restorations after home bleaching
Authors: BASTOS Natália Almeida , BITENCOURT Sandro Basso , BOMBONATTI Juliana Fraga Soares , DO NASCIMENTO Ana Paula Camatta , MATTOS Claudia Machado de Almeida , FREITAS Valéria da Penha , GUIMARÃES Jackeline Coutinho
Published: September 2020

ABSTRACT Objective The bleaching agents may interact with restorative materials, such as dental amalgam, providing an increase mercury ions (Hg) release, whose toxic effect is known. Whereas many patients have amalgam restorations (AR) and seek bleaching treatments, the present study aimed to evaluate in vitro the amount of Hg released from AR made with spherical alloy, after being subjected to different concentrations of carbamide peroxide (CP) for home bleaching. Methods 40 class I AR were prepared in bovine teeth. Afterthe restoration, the samples were randomly allocated into 4 groups (n = 10): C (control group), CP10 (CP 10%) CP15 (CP 15%) CP20 (CP 20%) and its treatments were simulated for 14 days for 6 hours daily. The Hg ions released was measured by energy dispersive X-ray spectroscopy (EDS) and surface changes were assessed in the Scanning Electron Microscope (SEM). Hg levels (percent mass) were recorded and the differences were statistically analyzed using the Kruskal-Wallis test and Dunn’s “Post hoc” test. Results Statisticalanalysis showed the bleaching treatment resulted in a higher Hg release (p <0.05), although no visible changes were identified in micrographs when comparing the control group with the other groups (CP10, CP15, CP20). Conclusion Increased Hg release may be observed during simulated home bleaching.
Multidisciplinary dental treatment for Papillon-Lefèvre syndrome: case report
Authors: MARTINS Paolla Leão , MOREIRA Francine do Couto Lima , CAMPOS Cerise de Castro , RORIZ Virgílio Moreira
Published: September 2020

ABSTRACT Papillon-Lefèvre syndrome is a rare autosomal recessive genetic disorder with a prevalence of one to four cases per million. It is characterized by diffuse or localized palmoplantar hyperkeratosis. It has no gender or racial predilection. Etiology and pathogenesis of Papillon-Lefèvre syndrome are still obscure. However, Papillon-Lefèvre syndrome is believed to be caused by a genetic defect located on chromosome 11, which is responsible for coding cathepsin C, a lysosomal protease present mainly in the epithelial regions such as the palms, soles of feet, knees, and keratinized oral mucosa, which are the most commonly affected areas in Papillon-Lefèvre syndrome. Periodontitis is an oral manifestation of Papillon-Lefèvre syndrome that results in early loss of deciduous and permanent teeth. This report aims to describe a case of an 11-year-old male patient diagnosed with Papillon-Lefèvre syndrome at 4 years of age. After the diagnosis, the child lost all deciduous teeth and sought dental service at the Federal University of Goiás 2 years ago. He is being treated using a multidisciplinary approach involving the areas of periodontics, pathology, and orthodontics to avoid loss of permanent teeth and to provide conditions for preserving the health of remaining teeth while maintaining the function and the esthetics.
Giallo & Subversivo - A série napolitana e a fabricação da “Febre Ferrante” no Brasil
Authors: Maranhão Andreia Pagani
Published: September 2020

RESUMO Com diversos best sellers no currículo, Elena Ferrante é uma das escritoras mais influentes da atualidade; não obstante, é anônima. Sua obra é exemplo do que chamamos literatura de transição, pois indica mutações, resquícios e sinais do presente, enfatizando deslocamentos e margens nas metamorfoses sociopolíticas, bem como conflitos civilizacionais e éticos do viver. Neste ensaio, pretende-se explorar alguns elementos do ‘hibridismo pop’ de sua obra, evidenciando aspectos que conformaram sua recepção no Brasil e a adesão febril aos seus escritos. O que ela denomina ‘desmarginação’ é apresentado como potência: permite a reaproximação do passado e o conhecimento de suas implicações na identidade, conduta e ética das pessoas comuns. Ação política munida da experiência histórica, a narrativa possibilita - no presente - alterações de rotas, rupturas prévias, resistências, bloqueios.
Casos de tuberculose com notificação após o óbito no Brasil, 2014: um estudo descritivo com base nos dados de vigilância
Authors: Aridja Ursila Manga , Gallo Luciana Guerra , Oliveira Ana Flávia de Morais , Silva Andressa Wanneska Martins da , Duarte Elisabeth Carmen
Published: September 2020

Objetivo. Caracterizar os casos com notificação pós-óbito da tuberculose no Brasil em 2014. Métodos. Estudo descritivo dos casos de tuberculose com notificação pós-óbito. Os dados são resultantes da vinculação do Sistema de Informação de Agravos de Notificação (Sinan-TB) com o Sistema de Informações sobre Mortalidade (SIM), e foram descritos segundo causa básica de óbito: tuberculose, aids e outras. Resultados. Nos 2.703 casos de tuberculose com notificação pós-óbito, observou-se maior proporção de pessoas do sexo masculino (73,5%), com mais de 39 anos de idade (80,8%), com escolaridade <8 anos de estudo (66,5%), de raça/cor da pele negra e parda (62,8%), que adoeceram de tuberculose na forma clínica pulmonar (75,2%); também prevaleceram notificações pelo serviço público (57,6%) e em municípios com índice de desenvolvimento humano >0,7 (66,6%). Conclusão. As características descritas das pessoas notificadas pós-óbito e a magnitude desse desfecho sugerem fragilidades dos serviços de atenção e vigilância da tuberculose
Use of complete SARS-CoV-2 genomes to estimate the Rt in Peru during March – April 2020
Authors: Romero Pedro , Sánchez-Yupari Milagros , Montero Stephanie , Tsukayama Pablo
Published: September 2020

Understanding the current SARS-CoV-2 pandemics dynamics using a multidisciplinary approach is essential to improve evidence-based policies. In our study, we estimated the SARS-CoV-2 effective reproductive number (Rt) in Peru using information from 69 complete genomes sequenced by INS-Peru and available in the GISAID public database. The tendency of Rt within March and April 2020 was similar to independent epidemiological reports. The Rt value decreased (Rt<1) during the first weeks of the pandemics in Peru but increases (Rt>1) before the beginning of April. More genomic information from Peruvian samples, available in public databases, that also represent the broad geographic diversity of Peru will allow better estimations based on genetic data and will complement epidemiological information.
Attitudes to open peer review among stakeholders of a scholarly-led journal in Brazil
Authors: Fontenelle Leonardo Ferreira , Sarti Thiago Dias
Published: September 2020

Scholarly journals should consider the attitudes of their communities before adopting any of the seven traits of open peer review. Unfortunately, surveys from the Global North might not generalize to the Global South, where double-blind peer review is commonplace even among journals on natural sciences and medicine. This paper reports the findings of a survey on attitudes to open peer review among four stakeholder groups of a scholarly-led medical journal in Brazil: society members and journal readers, authors, and reviewers. Compared to a previous survey recruiting mostly researchers on natural sciences from Europe, this survey found similar support to open peer review in general and for most of its traits. One important exception was open identities, which were considered detrimental by most participants, even more so in this survey than in the previous one. Interestingly, participants were not so dismissive of open identities when expressing whether they agreed with statements about its specific consequences. Because preprints are increasingly popular but incompatible with double-blind review, future research should examine the effects of transitioning from double-blind to open identities, especially on gender bias. Meanwhile, scholarly journals with double-blind review might prefer to begin by adopting other traits of open review or to make open identities optional at first.
Changes in Stage Distribution and Disease-Specific Survival in Differentiated Thyroid Cancer with Transition to American Joint Committee on Cancer 8th Edition: A Systematic Review and Meta-Analysis
Authors: Lechner Melissa G. , Bernardo Angeli C. , Lampe Alyssa , Praw Stephanie Smooke , Tam Samantha H. , Angell Trevor E.
Published: September 2020

Background

Recent revision significantly changed the American Joint Committee on Cancer (AJCC) staging criteria for differentiated thyroid cancer (DTC). To quantitatively evaluate resulting changes in patient stage distribution and the associated disease-specific survival (DSS) incorporating diverse populations, we performed a meta-analysis of studies comparing the AJCC 7th edition (AJCC-7) with 8th edition (AJCC-8) staging for DTC.

Materials and Methods

After PROSPERO registration (#CRD42019123657), publications in English reporting DSS of DTC with AJCC-7 and AJCC-8 from inception to June 2019 were identified by search of MEDLINE and PubMed. Random-effects meta-analyses were conducted to compare differences in survival between AJCC-7 and AJCC-8. Pooled hazard ratios, 10-year DSS, and corresponding interval estimates were calculated for AJCC subgroups. Differences in survival between editions were assessed using subgroup analysis with nonoverlapping confidence intervals indicating statistical significance.

Results

Final analysis included six studies with 10,850 subjects and median follow-up from 55 to 148 months. Use of AJCC-8 shifted classification to earlier stages: stage I, from 60% to 81%; stage II, from 5% to 13%; stage III, from 21% to 2%; stage IV, from 10% to 3%. Ten-year DSS was significantly lower in AJCC-8 versus AJCC-7 in patients with stage II (88.6%, 95% confidence interval [CI] 82.7–94.6% vs. 98.1%, 95% CI 96.6–99.6%, respectively) and stage III disease (70.5%, 95% CI 59.1–83.9% vs. 96.8%, 95% CI 94.1–99.64%, respectively).

Conclusion

Meta-analysis of revised AJCC staging for DTC, incorporating diverse populations, demonstrates redistribution of patients toward earlier clinical stages and better stratification of disease-specific mortality risk, specifically among patients now classified with stage II and III disease.

Implications for Practice

This study provides updated estimates of disease-specific survival for patients with differentiated thyroid cancer determined by the American Joint Committee on Cancer staging system that are generalizable to broader populations and support improved stratification using the recently revised criteria.
A REVIEW ON OPTIMIZATION LITERATURE RELATED TO OPERATIONS RESEARCH FIELD
Authors: PULAT Meryem , BAYYURT Dilayla , DEVECİ KOCAKOÇ İpek
Published: September 2020

Optimization is an iterative search process aimed at finding the best solution value for an objective function that satisfies constraints or bounded conditions in mathematically expressible problems. There are hundreds of books written in this field, and a new book is added to the list everyday. Since optimization is a very large field, each book is written for different disciplines. If you want to work on any subject related to this field, reaching the related book can be complicated and time consuming. The point to be reached in the research is to do an extensive research on the optimization books and to obtain relevant statistics. For this purpose, available optimization books related to the operations research of the last ten years were searched and examined in detail according to their topics. This work is aiming at leading the people who want to study about this topic by searching the literature about the optimization in the field of operations research.
SOSYAL PSİKOLOJİK YAKLAŞIMLA ÖZEL ARAÇTAN TOPLU ULAŞIMA: İZMİR ÖRNEKLEMİ
Authors: SOYLU Nihan Selin , KARASU Mehmet , ELCİ Cihan , GÖREGENLİ Melek
Published: September 2020

Kentleşmeyle birlikte özellikle büyük şehirlerde artan özel araç kullanımının meydana getirdiği yoğun trafik ve çok yönlü sorunlara sosyal, ekonomik ve çevresel olarak sürdürülebilir çözümler geliştirmek, dünyada ve ülkemizde giderek önem kazanmaktadır. Bu araştırma özel araç kullanımı ve toplu ulaşım tercihlerini farklı boyutlarıyla incelemenin yanı sıra toplu ulaşım seçeneklerinin nasıl daha cazip kılınabileceği sorusuna yanıt aramak üzere gerçekleştirilmiştir. Bu amaçla, İzmir’de yaşayan 571 kişilik bir örneklem grubuna internet aracılığıyla ulaşılmış; katılımcılara sosyo-demografik bilgi formu, toplu ulaşım sistemine dair memnuniyet formu, Kullanım Kolaylığı Ölçeği, Araba Kullanımının İşlevleri Ölçeği ve toplu ulaşımın teşvikine ilişkin açık uçlu soru formu uygulanmıştır. Sonuçlara göre, toplu ulaşımda kullanım kolaylığı arttıkça, toplu ulaşımdan memnuniyet düzeyi artmaktadır. Ayrıca araba kullanımının araçsal işlevinin, duygusal ve sembolik işlevleriyle olumsuz yönde ilişkili olduğu görülmüştür. Özel araç kullanımı davranışını açıklamak için ise yalnızca duygusal işlevin yordayıcı rolü olduğu görülmüştür. Araştırmanın sonuçları sosyal psikoloji ve ulaşım araştırmaları literatürleri çerçevesinde tartışılmıştır.
MÜLTECİLERİN KATILIMIYLA YÜRÜTÜLEN NİTEL ARAŞTIRMALARDA ETİK KONULAR
Authors: KUNUROGLU Filiz
Published: September 2020

Son yıllarda dünyada ve ülkemizde mülteci gruplar üzerine yapılan çalışmalarda artış yaşanmaktadır ve bu araştırmaların büyük çoğunluğunda nitel araştırma yöntemi kullanıldığı görülmektedir. Ancak araştırmacılar ve öğrenciler için bu araştırma süreçlerinde ortaya etik problemlere ve çözüm önerilerine yönelik çok sınırlı sayıda kaynak bulunmaktadır. Bu makale, mülteci grupların katılımıyla yapılan nitel çalışmalarda ortaya çıkabilecek etik meseleleri tartışmakta ve alan yazından örneklerle çözüm önerileri sunmaktadır. Ele alınan konular bilgilendirilmiş onam, gizlilik, duygusal sonuçlar konusunda farkındalık, kültür, dil, cinsiyet ve maddi teşvik meseleleridir. İlgili alınyazındaki kaynakların sınırlı olması sebebiyle alanda çalışan araştırmacılara ve eğitimcilere kaynak sağlamak amaçlanmaktadır.
REFLECTIONS OF TURKEY'S MIDDLE EAST POLICY ON THE PRESS IN THE 1950s
Authors: KASAPSARAÇOĞLU Murat
Published: September 2020

Democrat Party (DP) era is one of the contested periods in terms of politics, economy, society and foreign policy in Turkey. Particularly, the government-press relations and Turkey’s Middle East policy especially in the late 1950s consist serious challenges and crises. Initially, the DP government conducted a liberal press policy, but in the second half of the decade government-press relations strained. Similarly, Turkey’s Middle East policy can be regarded as a success story in the first half of the decade, while Turkey faced serious crises and challenges in the region in the second half. Despite several studies on government-press relations in the 1950sin the literature, there is a shortage of specific studies analyzing positions of the press towards DP’s Middle East policy. As a result, this paper aims to fill this gap and analyze the positions of the press regarding Turkey's Middle East policy throughout the decade in order to show divergence and convergence between the government and the press. Selected newspapers and journals published in this period will be used as primary sources. This paper concludes that the press in Turkey, regardless of their positions towards the government, supported DP's pro-Western and anti-communist Middle East policy despite some exceptions.
KÜRESELLEŞME TEORİLERİ: SÖYLEM VE İDDİALAR
Authors: KÖKALAN ÇIMRIN Füsun
Published: September 2020

Bu makalenin temel amacı, 1980’lerden sonra sosyal bilimler literatüründe giderek daha fazla oranda kendisine yer açmaya başlayan küreselleşme kavramını açıklamaya çalışan teorik tartışmaların değerlendirmesini yapmaktır. Ülkemizde özellikle Büyük Küreselleşme Tartışması olarak kavramsallaştırılan alan yazını içerisinde yer alan ünlü teorisyenler olan Held ve McGrew’in çalışmalarına sıklıkla atıflar yapılmaktadır. Ancak yazarların küreselleşmeye ilişkin açıklama modellerinin en azından Türkiye’de çoğu kez yanlış ya da eksik anlaşıldığı görülür. Elinizdeki bu çalışma, sosyal bilimler alanındaki bu bulanıklaşma ve yanlış anlamayı çözümlemeye yönelik olarak kurgulanmış mütevazı bir adım olarak değerlendirilebilir. Büyük küreselleşme tartışmasından yola çıkarak, bu çalışmada küreselleşme olgusunun toplumsal bir gerçekliğin adı olmadığı, aksine var olan toplumsal kurgunun bir eğilimi anlamına geldiği iddia edilmektedir. Dolayısıyla küreselleşme bir gerçeklik değil, bir yönelimin adıdır. Gündelik yaşamda ortaya çıkan derin ve çarpıcı toplumsal değişim dinamikleri, sosyal bilimcilerin bütün ilgisini bu alana kaydırmıştır. Böylece ortaya çıkan güçlü literatür içerinde ise çeşitli sınıflandırmaların yapılması ve kategorik/çözümleyici analizlerin gerçekleştirilmesi kaçınılmaz olmuştur. Elinizdeki bu çalışma, ifade edilen çözümleyici anlayışa katkı sunmayı amaçlarken, monist olmayan bir perspektifle kaleme alınmıştır. Günümüzde hem sosyal bilimler literatüründe hem de gündelik toplumsal yaşamda adeta akademik bir moda haline gelmiş olan küreselleşme kavramının sosyolojik bir analizini gerçekleştirmek bu çalışmanın temel kurgusunu oluşturmaktadır. Dolayısıyla da bu çalışmada mevcut toplumsal değişme dinamiklerinden öte, bu derin ve dramatik dönüşüm sürecini açıklamaya çalışan kuramsal tartışmalara yer verilmiştir. Çünkü küreselleşme tartışmasının çizgileri en azından Türkçe literatürde kesin olarak belirli ve açıklayıcı değildir.
Avoiding Sovereign Default Contagion: A Normative Analysis
Authors: De Ferra Sergio , Mallucci Enrico
Published: September 2020

Sovereign debt crises happen in waves, spreading from one country to the other. The euro-area debt crisis of 2011-12 is a good example of that. Stress in the sovereign debt market quickly spread from Greece and Ireland to Portugal, Spain, and Italy.
Matematik Öğretmenlerinin Teknolojik Pedagojik Alan Bilgi Düzeylerinin İncelenmesi
Authors: BAL Ayten Pınar , BEDİR Sümeyye Güner
Published: September 2020

Bu çalışmanın amacı, matematik öğretmenlerinin teknolojik pedagojik alan bilgi düzeylerinin belirlenmesi ve bu düzeylerin cinsiyet, mesleki kıdem, mezun olunan okul, görev yapılan okul ve hizmet içi eğitim durumu değişkenlerine göre incelenmesi ve bu konuda görüşlerinin alınmasıdır. Çalışma, karma araştırma yöntemlerinden açımlayıcı desene göre tasarlanmıştır. Araştırmanın nicel çalışma grubunu basit tesadüfü örnekleme yöntemine göre Akdeniz Bölgesinin iki büyük ilinde görev yapan toplam 190 matematik öğretmeni; nitel çalışma grubunu ise amaçlı örneklem yöntemlerin ölçüt örnekleme yöntemine göre belirlenen sekiz matematik öğretmeni oluşturmuştur. Araştırmada veri toplama aracı olarak Teknolojik Pedagojik Alan Bilgisi Ölçeği, kişisel bilgi formu ve yarı yapılandırılmış görüşme formu kullanılmıştır. Nicel verilerin analizinde betimsel istatistik, bağımsız gruplar t-testi, tek yönlü varyans analizi uygulanırken nitel verilerin analiz sürecinde ise içerik analiz tekniği kullanılmıştır. Sonuç olarak matematik öğretmenlerinin teknolojik, pedagojik alan bilgisi düzeylerinin yeterli olduğu; cinsiyet, mesleki kıdem, mezun olunan okul, görev yapılan okul ve hizmet içi eğitim durumu açısından ise istatistiksel olarak anlamlı farklılıklar oluşturduğu sonucuna ulaşılmıştır. Görüşme yapılan öğretmenlerin daha çok öğrenme ve öğretme sürecinde teknoloji kullanımının önemli olduğunu ve derse olan ilginin bu bağlamda arttığını vurguladıkları görülmektedir.
nf-vcf-novel-dataset-builder v1
Authors: Aguilar Ordoñez Israel
Published: September 2020

Nextflow pipeline used to build the novel variants dataset for the 100GMX project. 'nf-vcf-novel-dataset-builder' is a pipeline tool that builds a VCF file compiling only novel variants according to dbSNP and VEP, from a VEPextended annotated VCF file. This novel selection does not include singletons and private variants. The main output is in VCF format. Additional outputs include the dataset in TSV format, and a sequence coverage from gnomAD in these sites. Important note: input file must be previously annotated byhttps://github.com/Iaguilaror/nf-VEPextended All steps described are mk modules of code that will be done automatically through Nextflow pipeline.
VEPextended v1
Authors: Aguilar Ordoñez Israel
Published: September 2020

'VEPextended' is a tool, implemented in Nextflow, that annotates called variants using Variant Effect Predictor (VEP) and additional plugins that implement functionalities, that are not included in variation API. All steps described are mk modules of code that will be done automatically through Nextflow pipeline.
VCF2PCP v1
Authors: Ballesteros Villascan Judith , Aguilar Ordoñez Israel , Pérez-Villatoro Fernando
Published: September 2020

Nextflow pipeline that runs and plots admixture and smartpca from a compressed VCF.
Unlocking Spatial Molecular & Cellular Relationships of SARS-CoV-2 in Archived Human Tissue v1
Authors: Pattle Sam
Published: September 2020

The true prevalence of SARS-CoV-2 infection in the UK population remains unknown. Phylogenetic diversity estimates derived from genomic sequence tracking algorithms suggest possible arrival of viral strains in the UK several weeks earlier than the first confirmed cases. Diagnostic pathological specimens have continued to be recovered from patients throughout the Covid-19 pandemic, as part of standard investigation and workup across the normal range of clinical indications. Given the symptomatic heterogeneity and probable high rate of asymptomatic infections, we hypothesise that tissue biopsies have already been taken from living patients with clinically unrecognised SARS-CoV-2-infections. Here, we describe the protocol for a retrospective cohort study with the aims of i) detecting SARS-CoV-2 using qRT-PCR in archived biopsy tissue recovered from patients over the course of the pandemic to date, ii) demonstrating qualitative and quantitative evidence of SARS-CoV-2 tissue tropism and cellular-molecular patterns of infection using histological, in situ hybridisation and immunohistochemical techniques, and iii) linking those spatial molecular-cellular characteristics of SARS-CoV-2 infection to clinico-pathologic parameters. The results will provide new insights into the tissue tropism and rates of asymptomatic and ‘atypical’ SARS-CoV-2 infections - information that could immediately impact healthcare practices or public health policy.
Culturological orientators of modern Ukrainian cinema critics
Authors:   Institute of Culture Studies of the National Academy of Arts of Ukraine, Kokhan T. G.
Published: September 2020

The article analyses the position of Ukrainian scientists, represented in their works during the first two decades of the XXI century, when the influence of the basis of the cultural analyses on the development of cinema critics has become appreciable. The accent has been made on new approaches both to the history of Ukrainian cinema in trying to understand personalized approach prevails and to the estimation of subject direction of the films shoot on the boundary of the XX – XXI centuries. It is underlined that film expert's attention was concentrated on the further improvement of notion-categorical apparatus which provides investigations in film critics. It is shown that film science outlines some human problems which having historical cultural traditions, can appear as aesthetical-artistic reference points in creative process. It is declared that the important aspect of the article is dedicated to the fixation of the art studies formation history in the process of cinema development. The role of Danish producer Urban Gad, the author of the book "Cinema, its means and aims" is marked. It is indicated that while constantly shooting films U.Gad summarized his own experience of work in the cinema making in the first European investigation in the cinema studies. It is underlined that taking into consideration the dynamics of cinematograph's development, using of historical and cultural achievements of the past as reference points for modern cinema theory demands caution and correctness. In the context of this thesis systematization and analysis of works of Ukrainian film critics on the activities of national cinematograph's development are presented both actual and expediency. It is shown that using in the cinema study fundamental principles of cultural analysis in particular cross-scientific personalization a composed element of biographic method – to correlate cinema analysis with material of such human sciences as aesthetics, ethics and psychology. It is noticed that taking into consideration collective character of the creation in cinematograph the principle of personalization objectively appraises the contribution of each representative of the cinematic group within the creative process.
Borik Asit ve Boraks Pentahidrat Kristalleri için Kekleşmenin İncelenmesi
Authors: KUTLUAY Sinan , İZGİ M. Sait , ŞAHİN Ömer , CEYHAN A. Abdullah
Published: September 2020

Bu çalışmada, CMSMPR (sürekli-karıştırmalı, sürekli-ürün çekmeli) tipi kristalizörde, saf
ortamda üretilen borik asit ve boraks pentahidrat kristallerinin su alma
yeteneği, kekleşme derecesi tayini, ve mekanik dayanım, kekleşme, kırma
testleri yapılmıştır. CMSMPR sisteminde üretilen hem borik asit hem de
boraks pentahidrat kristallerinin su alma yeteneği, kekleşme, aşınma derecelerinin
yüksek olduğu ve bu kristallerin nemden oldukça etkilendiği ve bu nedenle habitinde
bozulmalar meydana geldiği görülmüştür. Ayrıca, kekleşme ve kırma testleri
sonucunda belirlenen akışkanlık durumları değerlendirildiğinde ise borik asit
kristallerinin kohezif (yapışan), boraks pentahidrat kristallerinin ise çok
kohezif olduğu tespit edilmiştir. Tüm bu sonuçlar esas alındığında, kekleşmeyi
önlemek için borik asit ve boraks pentahidrat kristallerinin yüksek nem oranlarına
maruz kalmaması gerektiği görülmektedir.
Conformable Kesirsel Mertebeden Tam Değer Fonksiyonlu Lojistik Modelin Kararlılık ve Çatallanma Analizi
Authors: KAYA Güven , KARTAL Senol
Published: September 2020

Bu çalışmada, conformable kesirsel mertebeden tam değer fonksiyonlu lojistik model ele alınmıştır. Modele tam değer fonksiyonlarının kullanılmasına dayalı bir ayrıklaştırma işlemi uygulanılarak bir fark denklem sistemi elde edilmiştir. Elde edilen bu fark denklem sisteminin pozitif denge noktasının yerel asimptotik kararlı olmasını sağlayan cebirsel koşullar Schur-Cohn kriterlerinin kullanılmasıyla elde edilmiştir. Yine çatallanma analizi ile sistemde r parametresinin değişimine bağlı olarak Neimark-Sacker çatallanmasının oluştuğu gösterilmiştir. Ayrıca kesirsel mertebeden türev parametresi ( α ) ve kesiklileştirme parametresi ( h ) nin sistemin dinamik yapısı üzerindeki etkisi araştırılmıştır. Elde edilen tüm teorik sonuçlar nümerik simülasyonlarla desteklenmiştir.
The Unity of Labor Law and Development of Atypical Employment: Interaction Problems
Authors: Chernykh N. V.
Published: September 2020

The paper investigates the issue of the unity of labor law in the context of development of legalization of so-called new, atypical forms of employment in European countries and their forthcoming (and partially already completed) legalization in the Russian Federation. The author has analized some negative features of atypical forms of employment, the preservation of which can threaten the unity and integrity of labor law. the paper highlights the inadmissibility of reducing the uniform standard of labor rights and focuses on problems in the institution of labour remuniration and protection. On the basis of the analysis of elements characterizing the unity of labor law, the author describes deviations from the classical features of labor relations that sometimes lead to shifting employers’ (entrepreneurial) risk on the person involved in hired labor.The author concludes that the extension of the scope of application of the provisions of Chapter 53.1 of the Labour Code of the Russian Federation (albeit in a very limited scope) to employees working in government authorities and the public sector is a very disturbing trend. Traditionally, the budget sphere is seen as low-paid stable employment. The introduction of non-permanent, atypical employment into the public sector reduces the low level of employment rights of employees in the public sector. The development of atypical forms of employment not only actively affect the informal employment sector, but also invade the field of “traditional” relations, setting incorrect directions of HR policies. In this regard, acts adopted by the legislator in the case of legalization of one of the atypical forms of employment must be strictly correlated with the fundamental principles of labor law, the concept of a uniform labor relation and basic rights of the employee, which will prevent the destruction of the unity of labor law.
Development of Procedural Law Foundations of Justice in Administrative Cases in the Context of the New Codification of Administrative and Tort Legislation
Authors: Pankova O. V.
Published: September 2020

The paper analyzes the necessity of a fundamental reform of the Administrative Code of the Russian Federation with its division into two codes (a substantive part — the Code of Administrative Offences of the Russian Federation, and a procedural part — the Procedural Code of Administrative Offences of the Russian Federation). With regard to the problem of modernization of procedural administrative and tort legislation, the author questions the main directions, objectives and prerequisites of the third codification in this field and draws the conclusion that the fundamental reform of the Administrative Code of the Russian Federation with the division of it into two codes — material and procedural — is premature and, in fact, political decision not grounded by feasible research results. The author highlights that the Concept of the new Code of Administrative Offences of the Russian Federation approved at the meeting of the Government of the Russian Federation in June 2019 primarily deals with the issues of reforming mainly substantive administrative and tort legislation, while proposals for the improvement of procedural regulation of administrative responsibility are not covered in details. The Concept does not contain information concerning the fact that instead of the current Code of Administrative Offences of the Russian Federation two new codes — the Administrative Code of the Russian Federation (CAO) and the Procedural Code of Administrative Offences of the Russian Federation (PCAO) — will be adopted.The author focuses on the analysis of the draft of the PCAO published on the website of the Ministry of Justice of Russia. Primarily, the paper highlights such provisions that deserve an affirmative response. However, the author devotes the most significant part of the study to the analysis of the conceptual shortcomings of the PCAO of the Russian Federation. Without elimination of these shortcomings, it can hardly been concluded that a complete and qualitative procedural and legal mechanism for the implementation of justice in the field of administrative and tort relations is established in the courts of general jurisdiction.
MEDIATED INTERACTION RITUALS: A GEOGRAPHY OF EVERYDAY LIFE AND CONTENTION IN BLACK LIVES MATTER*
Authors: van Haperen Sander , Uitermark Justus , van der Zeeuw Alex
Published: September 2020

The Movement for Black Lives has connected millions of people online. How are their outrage and hope mediated through social media? To address this question, this article extends Randall Collins’s Interaction Ritual Theory to social media. Employing semisupervised image recognition methods on a million Instagram posts with the hashtag #blacklivesmatter, we identify four different interaction ritual types, each with distinct geographies. Instagram posts featuring interactions with physical copresence are concentrated in urban areas. We identify two different types of such areas: arenas where contention plays out and milieus where movement identities are affirmed. Instagram posts that do not feature physical copresence are more geographically dispersed. These posts, including memes and selfies, allow people to engage with the movement even when they are not embedded in activist environments. Our analysis helps to understand how different forms of engagement are embedded in particular places and connected through the circulation of social media posts.