bluuebunny/crossref_metadata_2025 huggingface dataset:
Literature Study of Problem Based Learning Model Against Students Mathematical Motivation (Based on Indonesian Language Book)
Authors: Zebua Try Gunawan
Published: October 2020

This study aims to describe whether the Problem Based Learning Model can be used for students' motivation problems in learning mathematics, what kind of motivation is successfully provided by the Problem Based Learning Model, and how the Problem Based Learning Model can make students have motivation in learning mathematics. The research method used is the Literature Research Method, by conducting a literature review through books in Indonesian. To maintain the quality of the material being studied, Indonesian language books are often used as references and written by experts (for example professors) which are proven based on tracking activities carried out in various journals, books, and from the Higher Education Database (pddikti). Data analysis techniques were carried out in 3 stages, namely: organize, synthesize, and identify. The results showed that the  Problem Based Learning Model can be used for students' motivation problems in learning mathematics, intrinsic motivation is the type of motivation provided by the Problem Based Learning Model and the Problem Based Learning Model can make students have motivation in learning Mathematics because it is directly associated with the real world, so students feel mathematics is very useful and motivation will emerge.
Investigating English Teacher Candidate’s Use of Instructional Media During the Teaching Practicum: A Case Study
Authors: Ratih Ayu T Rachel , Tasnim Zakiyah , Rofiq Annur
Published: October 2020

This study analyzes the English teacher candidate’s use of instructional media in the teaching practicum. The English teacher candidate who became the participant in this study was doing their teaching practicum in MTsN 5 Jember. This study applied the qualitative case study design. Interview and observation were done one time to select the participant. The four-times classroom observations and questionnaires were used in order to collect the data. This study employed the model of Creswell in analyzing the data. The findings of this study showed that the English teacher candidate applied one type of instructional media namely Visual Media. Those were Picture and Whiteboard. The way the teacher candidate implemented the instructional media was almost the same in each meeting of the teaching and learning process. However, the students’ participation and response were not always the same in every meeting. It depended on the way the teacher candidate managed the class activity.
Developing Ethnomatematics-Based Flipbook in Circle Material at VIII Grade of Junior High School
Authors: S. A. M. M Maghfiroh , Suharman Agus , Ramadhona Rezky
Published: October 2020

Every ethnic group has  various shapes, sizes, and cultural patterns that are interesting to study. Incorporating cultural elements in learning mathematics as the representation of ethnomatematics is helpful to introduce cultural values to the younger generation implicitly. The combination of technology and ethnomatematics for creating learning media should be tried because it contain a positive values for attracting students' learning interest. This study purposes to develop ethnomatematics-based flipbook in circle material at VIII grade of junior high school. The results show that ethnomatemics-based flipbook is appropriate to apply. The validation result of material experts is 80%, validation of media experts is 77%, and and from the student questionnaire responses is 74%.
The Efforts in Improving the Civics Learning Achievement through Cooperative Learning Method of STAD Model (Student Teams Achievement Division) on the Grade VI Students of Semester 2 at SDN Karangsemanding 02 Jember in 2017/2018 Academic Year
Authors: Cahyono Setyagung Budi
Published: October 2020

Collaborative learning activities are able to trigger the active learning. Teaching and learning activities done in the classroom stimulate the active learning. Hence, doing the exercises or tasks within small groups and explaining the ideas to others are used to foster the students' activities. Based on the results of this research, the conclusions drawn were: (1) The cooperative learning method of STAD model improved the quality of Civics learning. (2) The cooperative learning method of STAD model gave a positive impact in improving the students’ learning achievements indicated by an increase in the student’s learning completeness on each cycle, involving cycle I (68.96%), cycle II (86.20%), cycle III (100). %). (3) The cooperative learning method of STAD model provided the students with the attention and opportunity to deliver their opinions, thoughts, ideas, and questions. (4) The students were able to work independently or within group, and be responsible on the individual and group assignments.
Redes de apoio social à família de pessoas com problemas decorrentes do uso de drogas: percepção de familiares cuidadores
Authors: Pires Ronaldo Rodrigues , Alencar Alexsandro Batista de , Carvalho Luana Vieira de , Rodrigues Francisco Diones Araujo , Lima Raquel Cerdeira de , Sampaio José Jackson Coelho
Published: October 2020

Objetivo: Compreender quais são as redes de apoio social utilizadas por familiares cujos membros fazem uso problemático de drogas e como estes avaliam o apoio recebido. Métodos: Trata-se de estudo de natureza qualitativa conduzido com familiares que acompanhavam usuários de um Centro de Atenção Psicossocial álcool e outras drogas. Foram realizadas entrevistas e a análise das informações coletadas foi baseada na técnica da Análise de Conteúdo. Recebeu aprovação ética com o parecer CAAE: 45607515.9.0000.5534.  Resultados: Os resultados indicaram que, por um lado, a própria família e instituições religiosas formam a principal rede de apoio social informal. Por outro, o Centro de Atenção Psicossocial álcool e outras drogas, Unidade de Pronto Atendimento e hospital psiquiátrico compõem a rede de apoio social formal. Estes últimos apresentam-se desarticulados e pouco acolhedores às demandas dos familiares. Considerações finais: As redes de apoio sociais dos sujeitos desta pesquisa são constituídas por um reduzido repertório de pessoas e lugares. Desse modo, impõe-se a reflexão sobre a urgência de integrar espaços do território como potenciais produtores de acolhimento e cuidado, envolvendo a pessoa que usa drogas, sua família e a comunidade.
Efficacy of mentoring skills in Indian Air Force suicide prevention training: Challenges and opportunities
Authors: Thomas B , Chaturvedula S
Published: October 2020

Introduction:

Mental health promotion and suicide prevention are important initiatives of Indian Air Force (IAF) for its personnel. Institute of Aerospace Medicine (IAM), Bengaluru, has been conducting suicide prevention training programs for the IAF personnel since 1997. More than a 100 programs have been completed. In-time identification of the vulnerable, empowerment of instructors, provision of information about suicide prevention and improvement of approach toward the ab initio who are at risk are the focus of the suicide prevention program (SPP). This paper aims at assessing the efficacy of the mentoring skills imparted during the suicide prevention training in successfully identifying and providing support to the vulnerable ab initio cadets in the training establishments of IAF.

Material and Methods:

Mentors (n = 34) who are instructors in the training establishments in IAF and who have completed SPP conducted by IAM participated in the study. A feedback tool which was to assess the usefulness of the SPP in terms of the extended use of mentoring skills in their work, problems faced in the identification of the vulnerable persons, challenges faced in their mentoring activities were administered. Qualitative analysis was carried out and compiled.

Results:

Qualitative analysis brought out certain important issues regarding the challenges faced by the mentors and their competency in effectively dealing with the challenges. The results provide support in improving the existing SPPs and the role of mentors in mental health promotion in IAF.

Conclusion:

Suicide prevention program being conducted at IAM (IAF) was found to be beneficial to the mentors. It also addressed some of the professional and personal challenges faced by them. The findings of the study has brought out important take home messages for refining the program in the future.
Accident of a civil passenger aircraft at a military airfield: The Casevac experience
Authors: Sarkar R , Mohapatra SS
Published: October 2020

Introduction:

There are many civil airports in India wherein the airfield and flying operations are controlled by the military whereas, the Airports Authority of India (AAI) controls the civil terminal. Accident of a civil aircraft on such a base poses unique challenges. This paper discusses the medical contingency plan of a Naval Air Station to deal with civil aircraft crashes based on a civil aircraft incident.

Case Details:

In the early morning of late Dec in 2016, a Mumbai bound civil flight (Boeing 737) took off from an Indian Navy controlled airfield. While initiating the take-off roll from RW, it veered off the runway towards right and came to halt along the perimeter road 230 m north of the runway edge, on hard rocky ground. There were 154 passengers and 7 crew members who were evacuated from the aircraft, through emergency chutes. Few passengers escaped through the over wing hatches. Twenty passengers sustained injuries, mostly involving the lower limbs. This was primarily due to jumping on hard rocky ground and falling and tripping on rocks while moving away from the aircraft. An analysis was done to understand the limitations on the existing medical contingency plan.

Discussion:

The ICAO Airport Services Manual Part 7 on Airport Emergency Planning (Doc 9137-AN/898 Part 7) is the guiding reference for all airports on Airport Disaster and Planning. The Medical Services portion delineates clearly the role of the Medical Aid Providers. In the instant case, the medical department had successfully handled the casualty evacuation and their medical management. SOP and the existing medical contingencies were effectively used. A post-accident analysis in the instant case revealed that 17 out of 25 checklist points were satisfied. The lessons learned from the incident have been discussed in the paper.
Percutaneous Bilateral Adrenal Radiofrequency Ablation in Severe Adrenocorticotropic Hormone-dependent Cushing Syndrome
Authors: Rosiak Grzegorz , Milczarek Krzysztof , Konecki Dariusz , Otto Maciej , Rowinski Olgierd , Zgliczynski Wojciech
Published: October 2020

Objectives:

The objectives of the study were to evaluate adrenal radiofrequency ablation (RFA) as a method of treatment in patients with severe adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome, among whom bilateral adrenalectomy is not a suitable option.

Material and Methods:

Five patients with ACTH-dependent Cushing syndrome underwent RFA of both adrenal glands. Four of them presented with Cushing disease unsuccessfully treated with pituitary surgery and medical therapy, while one patient had ACTH-dependent Cushing syndrome due to pancreatic endocrine tumor with liver metastases. All patients were disqualified from adrenalectomy due to morbid obesity or lack of consent.

Results:

A technical success was obtained in all cases, with only one re-intervention necessitated by a cooling effect of the inferior vena cava. Despite pre-procedural adrenergic blockade, severe hypertension was noted during the procedure in three cases, this being treated immediately using direct-acting vasodilators. No complications occurred otherwise. In all cases, significant improvement of clinical symptoms was observed, as well as marked decreases in levels of serum cortisol, free urine cortisol, and dehydroepiandrosterone sulfate.

Conclusion:

Bilateral RFA under CT-guidance is technically feasible and clinical improvement can be achieved using the method. In patients disqualified from adrenal surgery, RFA might be considered as an alternative method of ACTH-dependent Cushing syndrome treatment.
Analisys of the Implementation of Non-Communicable Disease Control Programs in Posbindu PTM Puskesmas Rokan IV Koto I Districs Rokan Hulu
Authors: Hosni Kholida , Afandi Dedi , Yunita Jasrida , Jepisah Doni , Hanafi Ahmad
Published: October 2020

The implementation of the Non-Communicable Disease Control Program carried out in Posbindu PTM is a concrete manifestation of community participation in implementing early detection, monitoring and early follow-up of Non-Communicable Disease risk factors independently and continuously. Rokan IV Koto I Community Health Center has implemented PTM control in an integrated manner but the scope of Non-Communicable Disease prevention and eradication efforts is still low at 53,9%. The purpose of the study was to determine the implementation of the control program for non-communicable diseases in Posbindu PTM Rokan IV Koto I Community Health Center seen from input indicators and processes of the Non-Communicable Disease Control Program. This type of research is qualitative. 8 informants consisted of midwives midwives in charge of posbindu, mobilizing midwives, monitoring midwives, counselor doctors, recording cadres, Head of Sub-Division of Administration, community leaders, BPJS. The tringulation used is source tringulation, methods and data. The results of the study show that inputs (human resources, incentives, facilities and facilities) have been done well even though the use of Posbindu PTM facilities and equipment is not yet available in every village. The process (identification of potential PTM problems, implementation of activities and program innovations, recording and reporting, early risk follow-up and referral of PTM) has gone well. BASMI PELAKOR 1 innovation was able to increase the coverage of community visits to Posbindu PTM to 57,4% which previously had been in 2018 at 53,92%. Suggestion for Community Health Center to facilitate the formation of partnerships in each village through CSR (Corporate Social Responsibility) to buy their own tools, deliberation with the community to determine the Posbindu PTM schedule that is mutually agreed upon, involve community participation in implementing BASMI PELAKOR.
Keywords : Implementaon of PTM Control Program, Input of PTM program implementaon. PTM program implementaon process.
Foot Massage Menurunkan Nyeri Post Operasi Sectio Caesarea Pada Post Partum
Authors: Sari Dewi Nurlaela , Rumhaeni Aay
Published: October 2020

ABSTRAK

Sectio caesarea merupakan tindakan alternatif dalam proses persalinan untuk menyelamatkan ibu dan janin. Ibu Bersalin dengan operasi sectio caesarea dilakukan pembedahan pada dinding abdomen dan dinding rahim. Dampak yang paling sering muncul dirasakan oleh postpartum dengan post operasi sectio caesarea adalah  nyeri. Nyeri akan berdampak pada bounding attachment terganggu, mobilisasi terbatas, Activity Daily Living (ADL) terganggu serta berpengaruh  terhadap Inisiasi Menyusui Dini (IMD). Asuhan yang diberikan terbatas pada terapi farmakologi dibandingkan  non farmakologi. Foot massage adalah salah satu terapi non farmakologi yang dapat membantu menutup gerbang di posterior horns dari sumsum tulang belakang dan memblokir bagian dari nyeri ke sistem saraf pusat. Tujuan penelitian ini untuk mengetahui pengaruh foot massage terhadap skala nyeri pada klien post operasi sectio caesarea di RS AMC. Penelitian ini merupakan penelitian pre eksperimen dengan pendekatan one group pre test post test design. Jumlah sampel yang digunakan berjumlah 27 orang dengan menggunakan teknik purposive sampling. Instrumen yang digunakan adalah Numeric Rating Scale (NRS) dan prosedur kerja foot massage. Responden dilakukan foot massage selama 20 menit selama 2 hari. Data di analisis dengan menggunakan uji wilcoxon. Hasil penelitian menunjukkan lebih dari setengah klien post operasi sectio caesarea berada di skala nyeri 6 sebelum dilakukan foot massage dan hampir setengah memiliki skala nyeri 3 sesudah dilakukan foot massage dan didapatkan nilai p value = 0.000, sehingga disimpulkan ada pengaruh foot massage terhadap skala nyeri pada klien post operasi sectio caesarea. Diharapkan rumah sakit dapat menjadikan foot massage sebagai salah satu alternatif manajemen non farmakologi dalam penanganan nyeri.

 

Kata kunci: Foot Massage; Post Partum; Nyeri; Sectio Caesarea
Dampak Tempat Pembuangan Akhir Sampah (TPA) Terhadap Gangguan Kesehatan Masyarakat
Authors: Axmalia Astry , Mulasari Surahma Asti
Published: October 2020

Kehadiran suatu tempat pembuangan akhir sampah (TPA) dalam suatu wilayah tentu akan menimbulkan masalah bagi penduduk sekitar, terutama yang menetap dengan jarak < 1 km. berdasarkan peraturan pemerintah No 18 tahun 2012 bahwa jarak pemukiman harus lebih dari 1 km. apabila tempat pembuangan akhir sampah tidak dikelola dengan baik, tentu akan menyebabkan pencemaran kualitas air, pencemaran udara, pencemaran tanah dari tumpukan sampah yang ditimbun. Studi literatur ini bertujuan untuk mengetahui dampak kesehatan pada masyarakat yang tinggal disekitar tempat pembuangan akhir (TPA) sampah dan faktor resiko yang dapat meningkatkan gangguan kesehata masyarakat. Metode yang digunakan dalam kajian ini adalah literature review. Pengumpulan literatur dilakukan melalui database http://garuda.ristekdikti.go.id dan Google Scholar yang diterbitkan dalam kurun waktu tahun 2015 sampai dengan 2019. Ditemukan keluhan gangguan Kesehatan pada masyarakat sekitar TPA yaitu penyakit kulit, diare, gangguan pernapasan, nyeri dada, mata pedih, tenggorokan kering, tenggorokan panas, kepala pusing, batuk-batuk, cacingan dan sesak napas. Terdapat faktor yang juga menyebabkan gangguan Kesehatan masyarakat disekitar TPA adalah faktor lingkungan seperti buruknya kualitas udara yang dipengaruhi oleh pencemaran air, pencemaran udara, pencemaran tanah yang dapat menyebabkan penyakit muncul akibat adanya penumpukan dan penimbunan sampah yang menyebabkan perkembangbiakan bakteri, vector penyakit dan virus.

 

Kata Kunci: TPA Sampah , Gangguan Kesehatan
ANALISIS FAKTOR YANG BERPENGARUH TERHADAP KONVERSI SPUTUM BASIL TAHAN ASAM PADA PENDERITA TUBERKULOSIS
Authors: Mahendrani Clevia Revi Maretha , Subkhan Mohammad , Nurida Annisa , Prahasanti Kartika , Levani Yelvi
Published: October 2020

Tuberculosis (TB) is caused by bacteria (Mycobacterium tuberculosis) that most often affect the lungs. The incidence of tuberculosis in Indonesia is high because the success rate of tuberculosis treatment has decreased which causes the chain of transmission continues to occur. The main government programs to decrese the incidence and increasing the success treatment with the Directly Observed Treatment (DOTS) program. One important indicator of the DOTS program to assessing the success of tuberculosis treatment is the conversion of positive AFB sputum to negative at the end of the intensive phase of treatment. AFB sputum conversion to negative at the end of the intensive phase of treatment is influenced by several internal factors such as level of education and income, gender, adherence, patient's nutritional status, and comorbidities. Then external factors can also influence the AFB sputum conversion in anti-tuberculosis treatment such as environmental conditions, smear positivity, drug taking supervisors (PMO), and availability of drugs in health facilities.
DEMAM TIFOID: MANIFESTASI KLINIS, PILIHAN TERAPI DAN PANDANGAN DALAM ISLAM
Authors: Levani Yelvi , Prastya Aldo Dwi
Published: October 2020

Typhoid fever is an acute infectious disease of the digestive system caused by the bacteria Salmonella typhi or Salmonella paratyphi. Typhoid fever is a global infectious disease in which an estimated 26.9 million cases of typhoid fever are found worldwide. Typhoid fever is especially common in developing countries because it is associated with poor sanitation. Clinical manifestations of typhoid fever that arise can vary from mild to severe symptoms. Symptoms of typhoid fever that are often found are fever, malaise, abdominal pain and constipation. Culture examination is a gold standard examination in establishing the diagnosis of typhoid fever. But this examination is rarely done. The first-line treatment option for typhoid fever is chloramphenicol. However, as the bacterial resistance to chloramphenicol increases, the main therapeutic choice for typhoid fever is the fluoroquinolone antibiotic.
POTENSI CIRCULATING MICRORNA SEBAGAI NOVEL BIOMARKER NON-INVASIF UNTUK DIAGNOSIS DAN PROGNOSIS PENDERITA MILD TRAUMATIC BRAIN INJURY: A SYSTEMATIC REVIEW
Authors: Enggy Liani Elisabeth , Gunawan Revina Raissa , Giffari M. Moh. Anfasa
Published: October 2020

Traumatic Brain Injury (TBI) masih menjadi salah satu masalah kesehatan masyarakat global akibat tingginya angka morbiditas dan mortalitas yang disebabkannya. Saat ini, Glasgow Coma Scale (GCS), CT-scan digunakan sebagai acuan utama dalam mendeteksi TBI, tetapi alat diagnostik ini kurang akurat dan belum mampu untuk mendeteksi tingkatan TBI ringan atau mild-TBI (mTBI). Diketahui 80% kejadian TBI merupakan kasus mTBI yang dapat menyebabkan disabilitas jangka panjang apabila tidak ditangani secara cepat dan tepat, sehingga diperlukan suatu biomarker baru yang dapat mengidentifikasi mTBI untuk membedakannya dengan orang sehat. Circulating miRNA merupakan salah satu jenis small non-coding RNA yang tersekresi dari jaringan menuju ruang ekstraseluler yang bersirkulasi dalam tubuh. Trauma pada pasien TBI dapat merubah ekspresi dan regulasi beberapa circulating miRNA spesifik, sehinga miRNA memiliki potensi untuk menjadi indikator diagnosis dan prognosis non-invasif dari mTBI. Menilai kemampuan diagnostik maupun prognostik circulating miRNA dalam mengidentifikasi mTBI dengan menilai sensitivitas, spesifisitas, dan AUC. Kajian sistematis ini mengumpulkan literatur dari PubMed, Science Direct, Directiory of Open Acces Journal (DOAJ), NLM, dan Epistemonikos dengan menggunakan metode berstandarkan cochrane guideline for systematic review (PRISMA) dengan pencarian kata kunci “Traumatic Brain Injury” dan “MicroRNAs”. Dari 307 studi yang didapatkan, ditemukan 6 final studi yang sesuai dengan seluruh kriteria inklusi. Studi yang dikaji berkorelasi dengan tujuan kajian sistematis ini. Circulating miRNA dari spesimen cairan berpotensi menjadi biomarker non-invasif baru untuk mTBI. Secara khusus, miRNA-425 dan miRNA-502 berpotensi tinggi untuk mendiagnosis awal mTBI terhadap orang sehat, serta miRNA-219 sebagai indikator menilai prognosis dari pederita TBI.
FREMANEZUMAG (FREMANEZUMAB DAN MAGNESIUM) SEBAGAI INOVASI DALAM PENCEGAHAN SERANGAN MIGRAIN
Authors: Rahman Putri Windiana , Qalbissilmi Safira
Published: October 2020

Migrain adalah penyakit yang dirasakan seumur hidup, sering berulang dan menghambat aktivitas penderitanya. Patogenesis migrain dispekulasikan berada pada sistem trigeminal dengan aktivitas neurotransmitter seperti CGRP, glutamat, serotonin dan nitrit oksida, vasodilatasi arteri serebri serta inflamasi neurogenic. Tata laksana migrain dengan konsumsi triptan didapatkan efek samping yang tak terduga antara penggunaan obat tersebut dengan kejadian iskemik serebrovaskular, jantung coroner dan hipertensi berat. Saat ini, telah ditemukan tata laksana terbaru dan sudah diakui untuk penyakit migrain. Pengobatan yang berhubungan dengan CGRP dan senyawa magnesium menawarkan manfaat yang cukup besar dibandingkan obat-obatan yang sudah ada.
KEGUNAAN GINKGO BILOBA UNTUK PENGOBATAN PENYAKIT NEUROLOGIS
Authors: Sarifuddin Muftia Jauristika , Annisa Nurul
Published: October 2020

Ginkgo Biloba adalah Salah satu tanaman yang tergolong sebagai fitofarmaka atau obat-obatan yang berasal dari tanaman ialah Ginkgo biloba Tanaman G.biloba (Gb) termasuk dalam familia Ginkgoceae. Di dalam ekstrak G.biloba terdapat antioksidan, antivirus, antiinflamasi, dan juga antikarsinogenik. Dan juga telah dinyatakan bahwa ekstrak G.biloba mempunyai efek yang baik terhadap fungsi SSP (sistem saraf pusat). Untuk mengetahui manfaat G.biloba dalam penanganan gangguan neurologis. Dibuat dengan menggunakan metode studi pustaka untuk mengumpulkan referensi yang valid mengenai tanaman Ginkgo Biloba yang dapat digunakan sebagai penanganan gangguan Neurologi. Hasil literature reviewberdasarkan studi pustaka yang dilakukan menunujukkan bahwa tanaman Ginkgo Biloba yang dapat digunakan sebagai penanganan penyakit neuorologis dengan kandungan dan efek terhadap tubuh. Dalam literature review ini didapatkan tanaman  Ginkgo Biloba yang dapat digunakan sebagai penanganan gangguan neurologis
POTENSI SOVATELTIDE (IRL-1620) SEBAGAI OBAT NEUROPROTEKTIF MUTAKHIR STROKE ISKEMIK
Authors: Hamonangan Jonathan Ricardo , Simanjuntak Michael Nobel , Giovanni Leonardus Yodi
Published: October 2020

Stroke adalah penyebab kematian tertinggi kedua di dunia. Stroke iskemik terjadi pada 88% kasus stroke, sedangkan stroke pendarahan terjadi pada 12% kasus. Baik pada dewasa maupun anak-anak, stroke dapat menyebabkan kecacatan sehingga memengaruhi produktivitas penderita. Namun, pengobatan stroke iskemik secara farmakologis merupakan tantangan bagi dunia kedokteran karena patologi stroke iskemik yang kompleks. Sebagai intervensi mutakhir, Sovateltide (IRL-1620/PMZ-1620) hadir sebagai agonis endothelin B receptors (ETBR) selektif yang prospektif dengan memberikan efek neuroprotektif dan angiogenesis pada stroke iskemik. Meskipun masih dalam uji coba klinis, belum ada studi pustaka yang membahas mengenai potensi Sovateltide sebagai neuroprotektif stroke iskemik. Sebagai solusinya, studi pustaka ini bertujuan untuk mengetahui potensi Sovateltide sebagai obat neuroprotektif mutakhir stroke iskemik. Studi pustaka secara sistematis ini merupakan hasil analisis dan sintesis dari berbagai referensi yang relevan dengan topik di Pubmed dan Google Scholar, dicari menggunakan berbagai kata kunci, dan jangka waktu tidak lebih dari 10 tahun. Sovateltide merupakan agonis ETBR yang paling selektif sehingga mampu memberikan efek neuroprotektif dengan meningkatkan proliferasi, survival rate, diferensiasi, neurogenesis, fusion mitokondria, dan perkembangan sel saraf. Selain itu, Sovateltide juga mampu meningkatkan Vascular Endothelial Growth Factor (VEGF) sehingga menyebabkan angiogenesis pada pembuluh darah otak yang mengalami oklusi. Berdasarkan penelitian, pemberian Sovateltide pada sampel tikus dewasa dan anak- anak dengan middle cerebral arteries occlusion (MCAO) berpotensi menjadi obat neuroprotektif stroke iskemik fase akut dan subakut. Sovateltide memiliki potensi yang baik sebagai obat neuroprotektif mutakhir stroke iskemik.
Physiological and physico-chemical changes in 1-methylcyclopropene-treated
guava (Psidium guajava L. cv. Queso de Bola) fruit stored at ambient condition
Authors: Zuniega J.S. , Esguerra E.B.
Published: October 2020

The marketability of guava fruit is influenced by its quality attributes desired by
consumers such as crispiness and crunchiness, green peel color, absence of defects, and
better taste. ‘Queso de Bola’ guava fruits were treated with 600 nL L-1
of 1-
methylcyclopropane (1-MCP) for 12 hrs then stored at ambient condition (29±2°C, 60-
80% RH). Reduced respiration rate with 1-MCP treatment was observed only starting on
the 5th day of storage. Ethylene production, however, was not suppressed. The continuous
decline in polygalacturonase activity with 1-MCP treatment coincided with firmness
retention of the fruit until the 15th day. Higher firmness of 1-MCP-treated fruits than
control fruits was further supported by higher sensory scores for crispiness and
crunchiness particularly towards the later part of storage. 1-MCP treatment did not prevent
peel browning as shown by similar polyphenol oxidase activity and pattern of change in
total phenolic content. Total soluble solids, titratable acidity, and pH were not affected by
1-MCP treatment and did not markedly change during storage. Ascorbic acid content
decreased in both treatments until day 6 followed by a slight increase with 1-MCP
treatment exhibiting higher levels than the control. In general, 1-MCP treatment prolonged
the marketability of guava by 3-4 days which was attributed to the maintenance of
firmness, retention of green peel color, and reduced disease incidence.
Entomopatojen Fungus, Beauveria bassiana (Balsamo)’nın İki Farklı İzolatının Myzus persicae Üzerine Ölümcül Etkileri
Authors: BERBER Gizem , BİRGÜCÜ Ali Kemal
Published: October 2020

Bu çalışmada Myzus persicae Sulzer (Hemiptera: Aphididae) üzerine entomopatojen fungus Beauveria bassiana’nın LD.2016 ve M6-4 izolatlarının etkinliğinin belirlenmesi amaçlanmıştır. Bu kapsamda B. bassiana’nın her iki izolatının 106, 107 ve 108 konidi.ml-1 dozları kullanılmıştır. Her bir doz ve kontrol grubu için denemeler 50 tekerrürlü olacak şekilde kurulmuştur. Her bir petri kabındaki yavrular 2. veya 3. nimf dönemine geldiğinde entomopatojen fungusun spor süspansiyonuna beş saniye süre ile daldırılmıştır. Yüzde ölüm oranlarını hesaplamak amacıyla uygulamadan sonraki 3., 5., 7. ve 9. günlerdeki canlı birey sayıları kaydedilmiştir. LD.2016 ve M6-4 izolatlarının 108 konidi. ml-1 uygulamasındaki LT50 değerleri sırasıyla 6.19 ve 5.5 gün olarak bulunmuştur. Elde edilen verilere göre, doz arttıkça uygulamadan sonraki 3., 5., 7. ve 9. günlerdeki ölüm oranlarının da arttığı belirlenmiştir. Uygulamadan sonraki 9. günde LD.2016 ve M6-4 izolatlarının 107 konidi.ml-1 dozlarına maruz kalmış bireylerin yüzde ölüm değerleri sırasıyla %58 ve %70 olarak bulunmuştur. LD.2016 ve M6-4 izolatlarının 108 konidi.ml-1 dozlarına maruz kalmış bireylerin yüzde ölüm değerleri ise sırasıyla %98 ve %92 olarak bulunmuştur. En iyi etki her iki izolatta da 108 konidi.ml-1 doz uygulamalarında görülmüştür. Sonuç olarak insanlara ve çevreye daha az zararı olan entomopatojen fungus B. bassiana izolatlarının M. persicae kontrolünde biyolojik mücadele etmeni olarak kullanabileceği düşünülmektedir.
Contributions to the Knowledge of Leaf Beetle (Coleoptera: Chrysomelidae) Fauna in Elazığ, Erzincan and Tunceli Provinces, Turkey
Authors: ASLAN Ebru Gül , KAYA Özgür Durmuş , ÜNAL Ebru
Published: October 2020

The study is based on leaf beetle material collected from Elazığ, Erzincan and Tunceli provinces of Turkey during 2018 and 2019. As a result of examined specimens 44 taxa are identified totally. The numbers of taxa according to the provinces are 23 from Elazığ, 15 from Erzincan and 11 from Tunceli. 19 out of 23 species in Elazığ, 12 out of 15species in Erzincan and all the reported species in Tunceli are new records. Notes regarding some species are provided under the title “remarks”. In addition, the presence of Galeruca spectabilis spectabilis (Faldermann, 1837) in Turkey is confirmed with the exact locality data. The present study aims to contribute Turkish leaf beetle fauna with new locality records.
Peyzaj Mimarlığı Öğrencilerinin Bilgisayar Destekli Tasarım Programları Üzerine Görüşleri: Burdur Mehmet Akif Ersoy Üniversitesi Örneği
Authors: BİNGÖL Bora , YÜCEDAĞ Cengiz , KAYA Latif Gürkan
Published: October 2020

Sürekli gelişen ve değişim gösteren dijital teknoloji araçları peyzaj mimarlığı tasarım ve sunum biçimlerini etkilemektedir. Önceleri sadece geleneksel tasarım yöntemleri yeterli iken, günümüzde çok yönlü bilgisayar destekli tasarım programları zorunlu hale gelmiştir. Bu çalışmanın amacı, bilgisayar destekli çizim, planlama, tasarım ve sunum süreçleri analiz edilerek, bilgisayar destekli tasarım programlarının peyzaj mimarlığı bölüm öğrencileri tarafından nasıl kullanıldığı ve proje çalışmaları üzerine etkilerini araştırmaktır. Bu amaçla, 2019-2020 öğretim yıllarında öğrenim görmüş 51 öğrenciye yüz yüze anket uygulanmıştır. Çalışmadan elde edilen sonuçlar dikkate alınarak, peyzaj mimarlığı bölümlerinde bilgisayar destekli tasarım araçlarının kullanılması ve uygulanması konularında değerlendirmeler ve öneriler yapılmıştır.
DIMENSIONED PARTICLE SWARM OPTIMIZATION FOR REACTIVE POWER OPTIMIZATION PROBLEM
Authors: Lenin K.
Published: October 2020

This paper present’s Dimensioned Particle Swarm Optimization (DPSO) algorithm for solving Reactive power optimization (RPO) problem.  Dimensioned extension is introduced to particles in the particle swarm optimization (PSO) model in order to overcome premature convergence in interactive optimization. In the performance of basic PSO often flattens out with a loss of diversity in the search space as resulting in local optimal solution.  Proposed algorithm has been tested in standard IEEE 57 test bus system and compared to other standard algorithms. Simulation results reveal about the best performance of the proposed algorithm in reducing the real power loss and voltage profiles are within the limits.
AQUIFER TRANSMISSIVITY VALUES FROM VES FOR PARTS OF PORT HARCOURT, RIVERS STATE, NIGERIA
Authors: P.O Eke , George F Life
Published: October 2020

This paper presents aquifer transmissivity values obtained from vertical electrical sounding method from some locations in Port Harcourt Local Government Area of Rivers State. Twelve (12) stations were occupied using the Schlumberger electrode configuration with maximum electrode spacing of 400 m. The data were interpreted using IPI2WIN software version 3.0.1 (2003).The results reveal four layer strata with transmissivity (Tr) values of between 145.53 and 18264.42 m2/day with average value of 7252.23 m2/day. These indicate high aquifer transmissivity values for the study area with high permeable and significant storability of the formations that enhances the migration and circulation of ground water within the region. The results indicate that the southern part of the study area is the most prolific in terms of groundwater exploitation and thus the most promising in sitting productive boreholes.
LUCID PARTICLE SWARM OPTIMIZATION ALGORITHM FOR SOLVING OPTIMAL REACTIVE POWER PROBLEM
Authors: Lenin K.
Published: October 2020

This paper presents, Lucid Particle Swarm Optimization (LPSO) algorithm for Solving Optimal Reactive Power Problem. Particle swarm   method is typically made up of a population of simple agents intermingle locally with one another and with their surroundings, with the aim of locating the optima within the operational environment. In this paper, a robust and Lucid particle swarm optimization framework based on multi-agent system is presented, where learning capabilities are integrated into the particle agents to dynamically fiddle with their optimality behaviours. Self-Sufficiency is achieved by the use of communicators that separate an agent’s individual operation from that of the swarm, thereby making the system more robust. The proposed Lucid Particle Swarm Optimization (LPSO) algorithm has been tested on standard IEEE 118 & practical 191 bus test systems and simulation results show clearly about the premium performance of the proposed algorithm in reducing the real power loss.
GROUNDWATER QUALITY ASSESSMENT FOR IRRIGATION PURPOSES AT THE WESTERN PORTION OF THE RIVER NILE– MINIA DISTRICT- EGYPT
Authors: Morsi Mamdouh Salama
Published: October 2020

The main goal of this research is assessment the groundwater resources for irrigation purposes at the western portion of the River Nile –Minia district- Egypt. The research depend on representation and calculation the resulted of chemical analysis of 96 groundwater samples collected from 96 pumping well During autumns 2011 from quaternary aquifer. the resulted reviled that; 25% of groundwater samples within the range of none restriction on use and the rest are margin according TDS content, most of samples are good for irrigation in all soils as they located in classes (C2-S1) and (C3-S1) and suitable for irrigation all crops as belong to SAR values and RSC hazard. But it restricted by boron ion concentration.
EXPERIMENTAL STUDY AND ANALYSIS OF FLAT BELT CONVEYER SYSTEM WITH DIFFERENT R.P.M.
Authors: Sharma Priyanka
Published: October 2020

In this paper, we are study about flat belt conveyer system with different R.P.M. such as 50,100,150,200,250 and 300 R.P.M. In this study, it is also included that the observations the different load carrying capacity (Grams) at different working time (Hours). The flat belt conveyer system is very important for the purpose of the material handling system from one place to other place, which is directly depended on the effective length of belt as 1800 mm. In this system we are used the D.C. motor drive system for the purpose of the loading and unloading condition of metallic hook , which is attached the lower portion of flat belt.
PENGEMBANGAN ALAT PENCETAK PIRING PELEPAH PINANG (Areca catechu L.) DENGAN MENGGUNAKAN METODE QUALITY FUNCTION DEPLOYMENT
Authors: Hafids Sahrial , Yernisa Yernisa
Published: October 2020

Peningkatan kesadaran akan dampak lingkungan yang terkait dengan produksi dan penggunaan piring plastik memunculkan gagasan untuk memproduksi piring ramah lingkungan dari bahan alami, seperti pelepah pinang (Areca catechu L.). Untuk membuat piring dari pelepah pinang dibutuhkan alat pencetak. Penelitian ini bertujuan untuk meningkatkan kualitas alat pencetak dengan menggunakan Metode QFD. Metode ini terdiri dari empat tahapan, yaitu: (1) Perencanaan Produk, (2) Perencanaan Teknik, (3) Perencanaan Proses, dan (4) Perencanaan Produksi. Berdasarkan hasil analisis kebutuhan pelanggan dihasilkan daftar lima prioritas kebutuhan pelanggan, yaitu: (1) tidak melelahkan, (2) tidak berkarat, (3) rangka kompak, kokoh dan stabil, (4) ergonomis, dan (5) cetakan yang dapat diganti. Terdapat lima karakteristik kualitas untuk memenuhi lima kebutuhan pelanggan, yaitu: (1) pengepres otomatis, (2) sasis ergonomis, (3) bahan cetakan tidak berkarat, (4) sasis kaku dan kuat, dan (5) desain minimalis. Oleh karena itu, dapat disimpulkan bahwa dengan menggunakan keempat fase Metode QFD alat pencetak piring dari pelepah pinang yang memenuhi kebutuhan pelanggan telah berhasil dikembangkan.
Böcekçil Beslenme ve Bazı Büyük Memeli Yaban Hayvanı Türlerinin Besin Tercihleri
Authors: ÜNAL Yasin , ARSLAN Dilek
Published: October 2020

Anadolu coğrafyasında yayılış gösteren memeli türlerin beslenme alışkanlıkları genel olarak etçil (carnivor), otçul (herbivor) ve hepçil/hem etçil hem otçul (omnivor) olmak üzere 3’e ayrılmaktadır. Böcekler, sahip oldukları yüksek protein dolayısıyla ekstrem hava şartları ve besin kıtlığında etçil ve hepçil memeli türü için alternatif bir besin ve enerji kaynağı olmakla birlikte, bazı zamanlarda hayatta kalabilmek için tek umut ve sonçare özelliğine sahiptir. Bu çalışmada 5 büyük memeli familyasına mensup 10 farklı türün besin tercihleri dışkı ve mide içeriği analizleri değerlendirilip besin grupları sınıflandırıldı. Böceklerin, ülkemizde yayılış gösteren önemli bazı büyük memeli türlerinin diyetindeki önemi değerlendirilmektedir.
Predictors of Early Mortality in Geriatric Patients after Hemiarthroplasty for Femoral Neck Fracture
Authors: TANOĞLU Oğuzhan , ARICAN Gökhun , ÖZMERİÇ Ahmet , ŞAHİN Özgür , İLTAR Serkan , ALEMDAROGLU Bahadır
Published: October 2020

Aim: Hemiarthroplasty is an appropriate treatment option for hip fractures that provides early mobilization, and good functional results. In the available literature, there are few studies that particulary investigate the risk factors affecting the 30-day mortality after hemiarthroplasty in geriatric patients with hip fractures. This study aimed to determine patient-related factors and biochemical predictors, which were easily accessible, inexpensive, and routinely examined in the perioperative period of 30-day mortality in geriatric patients after hemiarthroplasty for femoral neck fractures.
Methods: We enrolled 169 patients in our study, retrospectively. Age, body mass index, hospitalization time from admission to surgery, total hospitalization time, comorbidities, American Society of Anesthesiologists scores, blood transfusions, anticoagulant medications, albumin and plasma replacements, preoperative and postoperative hemogram, and biochemical tests were analyzed to determine the major predictors of 30-day mortality.
Results: The 30-day mortality rate was 14.2%. Multivariate analysis indicated increased age (>80 years of age) (1.095 odds ratio, p = 0.029), American Society of Anesthesiologists score (3.584 odds ratio, p = 0.007), and postoperative creatinine level (2.845 odds ratio, p = 0.001) as the major predictors of 30-day mortality after hemiarthroplasty for femoral neck fractures in geriatric patients.
Conclusion: Older age (>80 years of age), higher American Society of Anesthesiologists scores (ASA score 3 or 4) and increased postoperative creatinine levels were associated with an increased risk of 30-day mortality.
Gastroprotective effect of tarantula cubensis extract in the indomethacin-induced peptic ulcer model in rats
Authors: CANKARA Fatma Nihan , ÖZMEN Özlem , SAVAŞ Hasan Basri , ŞAHİN Yasemin , GÜNAYDIN Caner
Published: October 2020

Aim: Gastric ulcers are the most common gastrointestinal disease, due to several factors in the industrialized world. They may also occur after many pharmacological agents, combined with gastroprotective agents such as proton pump inhibitors (PPI) or anti-acids, are used as a preferred approach to maintaining gastrointestinal health. Unexpected adverse effects in these combinations make natural products an important alternative option.
Methods: Therefore, the main aim of this study is to investigate one natural compound, the Tarantula cubensis extract (TCE), in the experimental peptic ulcer model which was created by a single administration of indomethacin (40 mg/kg, body weight) to fed state Wistar-albino rats. The animals were pre-treated with two-doses of the TCE (0.2 ml/kg) before the indomethacin administration. After six hours, they were euthanized and the stomach tissue was isolated for biochemical and immunohistochemical analysis. Total antioxidant status/total oxidant status (TAS/TOS), prostaglandin E2 (PGE2), and nuclear factor kappa-B (NF-κB) levels were determined with ELISA in tissue homogenates. Caspase-3, cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS) and tumor necrosis factor-alpha (TNF-α), were visualized with immunohistochemistry in intact tissues.
Results: Pre-treatment with TCE increased PGE2 levels and decreased total oxidative status (TAS/TOS). Additionally, TCE alleviated the increase of (NF-κB) levels due to the indomethacin administration. Histopathological and immunostaining results showed that TCE mitigated elevated immunoreactivity of the caspase-3, COX-2, iNOS, and TNF-α which were the results of the indomethacin administration.
Conclusion: Our study demonstrated that pre-TCE treatment ameliorated indomethacin-induced peptic ulcers via antioxidant and anti-inflammatory actions.
Laws, Exceptions and Dispositions
Authors: Kistler Max
Published: October 2020

Can laws of nature be universal regularities and nevertheless have exceptions? Several answers to this question, in particular the thesis that there are no laws outside of fundamental physics, are examined and rejected. It is suggested that one can account for exceptions by conceiving of laws as strictly universal determination relations between (instances of) properties. When a natural property is instantiated, laws of nature give rise to other, typically dispositional properties. In exceptional situations, such properties manifest themselves either in an unusual way or not at all.
Depression – eine Signatur unserer Zeit?1
Authors: Leuzinger-Bohleber Marianne
Published: October 2020

Die LAC-Studie ist die wohl erste kontrollierte Psychotherapiestudie, die die Ergebnisse psychoanalytischer und kognitiv-verhaltenstherapeutischer Langzeitpsychotherapien bei chronisch Depressiven mit randomisierter und präferierter Zuweisung miteinander vergleicht. Beide Psychotherapieverfahren erwiesen sich als erfolgreich. Die Effektstärken und die vollständigen Remissionsraten waren höher als in anderen Studien. In zukünftigen Arbeiten werden nun Mediatorenund Moderatorenvariablen untersucht, um beschreiben zu können, welche therapeutischen Faktoren in welchem der beiden Verfahren zu welchen Effekten geführt haben. In diesem Artikel werden die mittlerweile auch ausführlich publizierten Erkenntnisse aus der LAC-Studie sowie das methodische Vorgehen knapp skizziert.
Der Gestalttherapeutische Ansatz bei depressiven Erfahrungen
Authors: Francesetti Gianni , Roubal Jan
Published: October 2020

Man unterscheidet Trauer und depressive Erfahrung, um damit das Kernstück des Leidens einer Person zu beschreiben, die sich in einer Depression befindet. In der Trauererfahrung wird eine Person oder Situation unerreichbar, und darin liegt der erlittene Verlust. Die Erfahrung einer melancholischen Depression ist anders: verlorengegangen ist das, was das Subjekt mit dem Gewebe verankert, das es mit der Welt verbindet. Es wird eine radikal relationale Herangehensweise zu Depressionen eingeführt, bei der untersucht wird, wie Klient*in und Therapeut*in sich im Hier und Jetzt der Therapiesituation gegenseitig deprimieren.
Gestalt Therapy Approach to Depressive Experiences
Authors: Francesetti Gianni , Roubal Jan
Published: October 2020

Mourning and depressive experience are distinguished to highlight the core of the suffering of people in depression. In the mourning experience a specific person or situation becomes unreachable and therein lies the loss suffered. The experience of melancholic depression differs: what is lost is that which anchors the subject to the fabric which connects him/her to the world. A radically relational approach to depression where the client and therapist are seen as depressing here and now in the therapy’s situation is introduced.
Depression – ein komplexes dynamisches System
Authors: Schiepek Günter
Published: October 2020

Der vorliegende Beitrag befasst sich mit neueren Befunden zur Depressionsforschung, vor allem zur psychotherapeutischen Behandlung von Depression. Auf Wunsch der Redaktion sollte damit auch eine Synopse der wissenschaftlichen und praktischen Entwicklungen gegeben werden, die am Institut für Synergetik und Psychotherapieforschung der Paracelsus Medizinischen Privatuniversität Salzburg und der kooperierenden Forschergruppen stattfinden. Ein Schwerpunkt liegt in der Personalisierung der Psychotherapie und betrifft sowohl neuere Methoden der Fallkonzeption (z.B. idiografische Systemmodellierung und deren computerbasierte Visualisierung) als auch Verfahren des hochfrequenten Prozessmonitorings und Prozessfeedbacks. Hierfür wurde das Internetund App-basierte Synergetische Navigationssystem (SNS) entwickelt und erprobt. Die Verläufe der Psychotherapie depressiver Patient*innen zeigen diskontinuierlich Sprünge dynamischer Muster (sogenannte Ordnungsübergänge), die von einer erhöhten kritischen Instabilität (dynamische Komplexität) und zeitlich begrenzter Synchronisation der Items eines Prozessbogens eingeleitet werden. Erhöhte kritische Instabilität ist zudem prädiktiv für besseren Therapieerfolg. In einer Studie an komorbid depressiven Patient*innen mit Zwangsstörungen wurde deutlich, dass sich neben klinischen Verbesserungen auch die funktionelle Konnektivitätsdynamik neuronaler Netze verändert. Wiederholte fMRT-Scans zeigten, dass Flexibilität und Fluidität der Neurodynamik mit der Psychopathologie (z.B. Depressionsintensität, BDI) negativ assoziiert sind, aber im Verlauf von Psychotherapie zunehmen. Abschliessend erfolgt eine Einschätzung von Möglichkeiten, nichtinvasive Neurostimulation mit Psychotherapie zu kombinieren.
Antworten auf die Kommentare von Greiner und Burda (Heft 2/2019)
Authors: Erismann Markus
Published: October 2020

Im vorliegenden Artikel setze ich mich mit den wissenschaftstheoretischen Kommentaren von Greiner (2019) und Burda (2019) auseinander. Greiner unterscheidet mit Bezug auf Wallner «Wissen» und «Erkenntnis». Dies entspricht meiner Auffassung von Reflexion auf die psychotherapeutische Praxis. Durch diese Reflexion wird «Erkenntnis» gewonnen. Hinsichtlich Burdas Konzept der Selbst-Differenz, das mehr auf Auflösung statt auf Bildung von Identität bedacht ist, stellt sich die Frage, wie dieses Konzept auf die psychotherapeutische Praxis anwendbar ist.