bluuebunny/crossref_metadata_2025 huggingface dataset:
Intento de suicidio pediátrico e ingreso a Unidad de Cuidado Intensivos, antes y después de la pandemia, en un hospital universitario en Boyacá, Colombia
Authors: Mojica Walteros Carlos M. , Hoyos Gómez Laura K. , Vanegas Gama Henry S. , Muñoz Torres Laura D , Fernández-Ávila Daniel G.
Published: January 2024

Introducción: La pandemia por COVID-19 ha tenido un impacto profundo en el ámbito de la salud mental de niños y adolescentes, teniendo en cuenta que el confinamiento interrumpió de manera abrupta su entorno escolar y social, experimentando sensaciones como ansiedad, irritabilidad y estado de ánimo triste, lo que se ha relacionado con el aumento de intento suicida.  Objetivo: caracterizar clínica y socio demográficamente la población en edad pediátrica que sufre intento de suicidio e ingresa a la unidad de cuidados intensivos, antes y durante la pandemia Métodos: Estudio descriptivo de corte transversal. Se incluyeron todos los pacientes entre 0 y 18 años que ingresaron a unidad de cuidados intensivos por intento suicida. Resultados: Se incluyeron 55 pacientes de los cuales 82.1 % intentaron suicidarse durante la pandemia por COVID-19. El ciclo de vida adolescencia y el sexo femenino fueron los más afectados. La mayoría de los intentos suicidas ocurrieron dentro del hogar, siendo la intoxicación el mecanismo más frecuente y los medicamentos la sustancia más utilizada. El lavado gástrico fue el tratamiento más frecuente y solo un intento suicida fue fatal. Conclusión: Durante la pandemia por el nuevo coronavirus aumentó el número de intentos suicidas en la población pediátrica. Los adolescentes y el sexo femenino son la población que con mayor frecuencia intenta suicidarse, siendo los medicamentos la sustancia que más utilizan, por la facilidad que tienen para su acceso dentro del hogar.
Microbiota intestinal y obesidad infantil: implicaciones etiopatogénicas y terapéuticas
Authors: Martín Martín María , Palomo Atance Enrique
Published: January 2024

Antecedentes: la obesidad infantil se presenta como una enfermedad de creciente prevalencia en el siglo XXI. No obstante, este incremento no es directamente proporcional a la ingesta calórica ni al sedentarismo, lo que ha supuesto el inicio de nuevas líneas de investigación, situando a la microbiota intestinal como un nuevo factor de riesgo para la obesidad en edad pediátrica. Tema: Se ha realizado una revisión bibliográfica a través de una búsqueda en la literatura científica desde 2013 hasta 2021. Se han utilizado las bases de datos médicas PubMed, Scielo, Elsevier y Cochrane, obteniendo así 27 artículos finales. La diferencia cardinal entre pacientes obesos en comparación con pacientes con normopeso es el aumento del ratio Firmicutes/Bacteroidetes. La microbiota intestinal interviene en la etiopatogenia de la obesidad infantil mediante cinco mecanismos principalmente: modificaciones en la composición bacteriana, producción de metabolitos, aumento del tono endocannabinoide, reducción de la expresión del factor adipocitario inducido por ayuno y modulación del tracto gastrointestinal.
Las estrategias terapéuticas dirigidas a tratar la obesidad capaces de modificar la disbiosis son la administración de prebióticos y probióticos, el trasplante de microbiota fecal y el ejercicio físico.  Conclusiones: hoy los datos todavía no son concluyentes dada la escasez de estudios. Es necesario realizar nuevas investigaciones de carácter experimental y, una vez obtenidos resultados más concretos, implementar los ensayos clínicos de las opciones terapéuticas frente a grupos bacterianos específicos.
Hernia diafragmática congénita derecha: reporte de un caso exitoso tratado por toracoscopia.
Authors: Garcia Rairan Luis Alejandro , Gonzalez Cruz Maria Angelica , Alfonso Diaz Alejandra , Angulo Maria Cristina , Silva Sebastian , Delgado Andres Mauricio
Published: January 2024

Antecedentes: La Hernia Diafragmática Congénita es un raro defecto anatómico del diafragma que resulta de la ausencia o subdesarrollo de una parte o la totalidad de la cúpula diafragmática. Este defecto provoca la herniación de órganos abdominales en la cavidad torácica, lo que puede llevar a complicaciones pulmonares y cardiacas graves en los recién nacidos.
Reporte de caso: Presentamos el caso de un recién nacido de 37 semanas con antecedentes prenatales de cardiopatía congénita, sospecha de coartación aórtica y un doppler de la arteria cerebral media anormal. Pocos minutos después del nacimiento, experimentó insuficiencia respiratoria y requirió apoyo ventilatorio. Además, una radiografía de tórax reveló la presencia de vísceras abdominales en el hemitórax derecho, lo que generó sospechas de una Hernia Diafragmática Congénita Derecha, confirmada posteriormente mediante ecografía. El recién nacido fue sometido a una toracoscopia para corregir el defecto diafragmático, logrando una corrección completa de la hernia sin complicaciones y una adecuada recuperación posoperatoria. Fue dado de alta después de solo unos días de hospitalización.
Conclusión: Sugerimos la realización de diagnósticos precoces y la atención del parto en centros de mayor complejidad para aumentar las posibilidades de supervivencia.
A Cotton Rope in the Colon: A Rare Cause of Chronic Abdominal Pain
Authors: Syed Imran Ali , Rafi Kashif , Wasif Khan Hafiz Muhammad , Malik Ahmad Karim , Aujla Usman Iqbal
Published: January 2024

Retained surgical sponge is a relatively rare medical condition with potential serious medicolegal implications. The term “gossypiboma” is frequently used to describe this condition. We present a case of a 40-cm-long retained surgical sponge in a 43-year-old woman who presented with unexplained chronic abdominal pain for several years. She had a history of open cholecystectomy, hepaticojejunostomy, and enteroenterostomy. Computed tomography scan revealed a large cotton sponge anchored within the large bowel. Surgical exploration is usually required for the retrieval of gossypiboma. However, it was successfully removed endoscopically using a diathermic needle knife with no immediate complications. The patient was discharged after 48 hours with marked improvement in her abdominal pain. This case emphasizes the emerging role of novel endoscopic interventions, resulting in excellent clinical outcomes, avoiding major surgical interventions, and providing cost-effective benefits.
Development of Social Interaction and Behavior for Early Childhood Education in the Era Society (5.0)
Authors: Al Umairi Mushab
Published: January 2024

This research is based on the inability of young children to have good social interaction and behavior towards the environment, school, family, and society in the era of Society 5.0. To help reduce a child's inability to engage in social interaction and good social behavior. So, help from adults is needed. In providing this assistance, parents or teachers should understand the process of developing social interactions and social behavior for young children. This research aims to determine the development of social interaction and social behavior toward early childhood education in the era of Society 5.0. The type of research used in this research is field research. Then, to obtain data, this research used observation, interviews, and documentation methods. This research was analyzed using descriptive qualitative (in the form of opinions or written opinions from people and the actions observed). This research concludes that providing social interaction and good social behavior will positively impact early childhood education in the era of Society 5.0.
Directores de escuela como traductores de las políticas de inclusión: Compromiso condicionado, premiar la inclusión y privatizar la traducción
Authors: Inostroza Fabian , Pávez Paula
Published: January 2024

El objetivo de esta investigación fue conocer la traducción que producen los directores de escuela en torno a las políticas de inclusión escolar en el sistema educativo chileno. En términos teóricos se empleó la noción de traducción proveniente del enfoque policy enactment o la puesta en acto de las legislaciones, para comprender las traducciones que produjeron los participantes en torno a estas normativas. Metodológicamente, se realizó un estudio de tradición cualitativa consistente en la aplicación de entrevistas semiestructuradas a 40 directores y directoras de escuelas públicas y subvencionadas de distintas regiones de Chile. Entre los principales hallazgos se destaca en primer lugar, un compromiso condicionado por parte de los participantes hacia el cumplimiento de las políticas manifestando estos adhesión y resistencias. En segundo lugar, se evidenció que los directores sostenían que la inclusión sería una prioridad en las escuelas si se premiara por su cumplimiento por medio de bonos o vouchers, y en último lugar, se identificó que algunos de los participantes transfieren la responsabilidad de la traducción de las políticas a actores externos a la institución educativa, como lo son las Asesorías Técnicas Educativas, privatizando de esta forma la tarea de interpretar y generar significados y prácticas en torno a estas políticas.
COVID-19 learning loss and recovery in Brazil: Assessing gaps across social groups
Authors: Miranda Eveline de Medeiros , Baum Donald R.
Published: January 2024

Students in over 150 countries experienced school closures throughout the COVID-19 pandemic. In the years following, a growing body of literature seeks to estimate the impacts of these education disruptions on a diverse set of outcomes, including student learning. This article adds to this research by examining causal evidence through a difference-in-differences framework (DID). Results suggest that school closures led to learning losses in math for high school seniors in public schools in the Federal District (DF) in Brazil. And while all racial groups experienced learning loss, White and Asian students experienced the most significant losses in 2020. We find no evidence of learning recovery from 2020 to 2021 for any racial groups, suggesting that learning losses persisted into school reopening. We do find, however, possible signs of recovery for female senior students compared to male students. Nevertheless, male and female performance differences are still prominent when analyzing data from 2016 to 2021. The utilization of critical policy analysis and the effectively maintained inequality frameworks can offer insights into significant learning disparities experienced by students.
Intervención con población vulnerable a la violencia y la exclusión
Authors: Martínez-Otero Pérez Valentín , Cayón Peña Juan
Published: January 2024

Comprender qué provoca la vulnerabilidad es un paso esencial para ayudar a las personas y a las comunidades a adquirir las estrategias y los recursos necesarios para evitar o minimizar los daños. La vulnerabilidad es objeto de preocupación en el campo social. Hablar de vulnerabilidad será positivo si, por un lado, permite enriquecer la comprensión de circunstancias personales, institucionales y sociales de exclusión, y, por otro lado, anima a disponer los elementos necesarios para prevenir y eliminar barreras. Tal como nosotros la entendemos, la vulnerabilidad, a despecho de las críticas recibidas, no tiene sentido peyorativo. Es posible que en ocasiones se identifiquen resistencias, incluso en los propios sujetos, a hablar de personas vulnerables, sobre todo, si la denominación, desde una óptica “capacitista”, queda asociada a limitación, debilidad, pasividad, deficiencia, inferioridad, etc. En este cuarto volumen, a partir del concepto de vulnerabilidad, adoptamos, al igual que en las obras anteriores de esta misma colección, una mirada pluridisciplinar y nos centramos en planteamientos inclusivos, asentados en la dignidad personal, en los derechos, en el empoderamiento, en la resiliencia individual y colectiva, así como que en la consideración de concretas situaciones. Se trata de subrayar que las ciencias sociales y humanas pueden realizar una labor muy positiva en lo que se refiere a la prevención de la violencia y la exclusión.
Pengaruh Penambahan Sodium Lauryl Sulfat terhadap Karakteristik Sabun Padat pada Mata Kuliah Praktikum Analitik Proses
Authors: Suryadi Joko , Andrijanto Eko
Published: January 2024

Solid soap as a result from process analysis practicum can be produced using with hot process method using raw material of palm oil and a strong base in the form of NaOH. The aim of this research is that apart from fostering student inquiry regarding the soap making process, they are also able to analyze the parameters of solid soap over a certain period based on variations in the amount of added surfactant. The methods used in practicum activities are dividing practicum groups, making solid soap, and collecting practicum reports. In the activity of making solid soap, the concentration of sodium lauryl sulfate (SLS) was varied for each group, 0, 1, 2 and 3% w/w respectively. The parameters measured in this research were the pH value, water content, ability to form foam, free fatty acid content and ethanol insoluble material in solid soap. The pH characterization of the results of the saponification process shows that soap at all variations in SLS concentration is predominantly alkaline. The characterization carried out showed that the levels of free fatty acids and ethanol insoluble substances met SNI 3532:2016 standards. Water content parameters do not meet these standards because the measurements were carried out during practical activities and without the process of holding the soap product. From the results of observing these parameters, in general it can be concluded that the solid soap products resulting from the practical work have the best quality under the condition of adding SLS with a concentration of 1%.
International Humanitarian Law’s Impact on the Development of Artificial Intelligence in Weapon Guidance Systems
Authors: Munstedt Danielle
Published: January 2024

There is a growing interest in developing artificial intelligence (AI) weapon guidance systems in the military domain. Current guidance systems employ various methods to guide a weapon to its target. This target accuracy is a critical factor for its effectiveness. Artificial intelligence capabilities could enable these systems to perform tasks that usually require human intelligence, such as identifying potential threats or targets on the battlefield while continually improving the system’s performance at its assigned task.
Carthamin yellow attenuates brain injury in a neonatal rat model of ischemic–hypoxic encephalopathy by inhibiting neuronal ferroptosis in the hippocampus
Authors: Zhou Yuanyu , Wang Yuebin , Wu Xiaoqing , Wu Junjie , Yan Jianhui , Su Wei
Published: January 2024

Hypoxic–ischemic encephalopathy (HIE) is a common neurological disorder characterized by ischemia and hypoxia in the perinatal period, which seriously affects the growth and development of newborns. To date, there is no specific drug for the treatment of HIE. Previous studies have shown that ferroptosis plays an important role in the pathogenesis of HIE. Carthamin yellow (CY) is believed to have antioxidant and anti-inflammatory effects. However, no studies have reported the role of CY in ferroptosis in HIE in vivo until now. The aim of this study was to investigate the effect and mechanism of CY on HIE in vivo and to provide an experimental basis for the clinical treatment of HIE. The results demonstrated that CY increased the expression of NeuN in the neonatal rat hypoxic-ischemic brain damage (HIBD) model. Further exploration revealed that CY increased the expression of glutathione peroxidase 4 and ferritin heavy chain 1 while it decreased the expression of PTGS2 and ACSL2. Moreover, CY decreased malondialdehyde expression and increased superoxide dismutase and glutathione expression in vivo. The findings also indicated that CY downregulated the expression of Nrf2 and Keap-1. In conclusion, this study demonstrated that CY attenuated brain injury in an experimental HIBD model, potentially by alleviating hippocampal neuronal ferroptosis through inhibition of the Nrf2/Keap-1 signaling pathway. These findings provide a novel therapeutic strategy for the clinical treatment of HIE.
Richard Rodriguez in “Borderland”
Authors: de Castro Juan E.
Published: January 2024

Starting with Days of Obligation: An Argument with My Mexican Father (1992), the recent writings of Richard Rodriguez not only have stressed the centrality of cultural interaction and exchange, but have also resorted to Jose Vasconcelos’s notion of the “cosmic race” in their analyses of contemporary American reality. Although his essays havepoints in common with theories of the “border”and of the “borderlands,” Rodriguez’s celebration of hybridity has not led him to automatically embrace progressive public policies. On the contrary, he now bases his criticisms of affirmative action and bilingual education on the “cosmic race”and the concomitant emphasis on cultural hybridity. However, he has also become a defender of immigrant and gay rights. Rodriguez’s writings question the frequent assumption of a necessary linkage between the acknowledgment of hybridity and the defense of multiculturalism. But they also question what is “conservative” or ‘progressive” within the Chicano community.
Los Atravesados
Authors: Rivera Lysa
Published: January 2024

This essay examines how Guillermo Gómez-Peña’s ethno-cyborgs, performance personae that first appeared in his work in the mid-1990s, exploit and critique two overlapping cultural-political movements: the emergence of Internet technologies (cyberculture) and the passage of the North American Free Trade Agreement (NAFTA). After locating the conception of the ethno-cyborg following the 1994 production of Temple of Confessions, I trace their development throughout Gómez-Peña’s work in the 1990s, ending with the 1997 publication of Friendly Cannibals. I argue that the ethno-cyborgs reveal and challenge a fundamental conflict that preoccupies Gómez-Peña, namely the co-existence of white nationalist discourse and globalization in a post-NAFTA U.S. society. The ethno-cyborgs’ ability to exploit and critique (and even offer an alternative to) this paradox speaks to their relevance even today, in a post-9/11 U.S. society that styles itself “postrace.” In order to counter this illusion, the ethno-cyborgs embody and enact the process of racial formation—the production and management of “racialized” others through representation—as it pertains to the Chicana/o subject. In doing so, the Chicano-centric ethno-cyborgs insist on recognizing the persistence, even proliferation of cultural borders that continue to marginalize, manage, and limit Chicana/o lived experience in a white hegemonic society.
The Curandera of Conquest
Authors: Hartley George
Published: January 2024

In this essay I argue that the primary role that Gloria Anzaldúa creates for herself as a writer and activist is that of the curandera of conquest, the healer of la herida abierta (the open wound) created by the borders imposed by capitalism, nationalism, imperialism, sexism, homophobia, and racism. After examining Anzaldúa’s Prietita and the Ghost Woman as both an illustration (in content) and an example (in enactment) of her practice as a curandera, I provide a brief overview of curanderismo and key developments in the theories of decolonization within global indigenous studies since the turn of the twenty-first century. I read Anzaldúa’s decolonizing work as a companion to this recent decolonization move within indigenous theory and practice.
Framing Peace as Violence
Authors: Ana Otto Santa , López Layza , Munguía Edgar
Published: January 2024

This study examines two successive days of U.S. television news coverage of the May 1, 2007, immigration rights rally in Los Angeles. As thousands of demonstrators appealed peacefully for comprehensive immigration policy reform, they were assailed by 450 police officers firing munitions and using truncheons. We evaluated fifty-one television news reports from three networks and five local stations using three complementary analyses (framing, visual coding, and critical spoken discourse analysis). News reporters on the ground at the time framed the events as a police attack. On the following day, however, news media blamed the victims by reframing the event as a violent provocation. We argue that the television news seized political agency and manipulated public opinion about domestic immigration policy.
Проєкт Вернадського «Українська академія наук»: до 160‑річчя від дня народження академіка В. І. Вернадського
Authors: Онопрієнко В. І. , Савчук В. С.
Published: January 2024

Розглянуто організаційне становлення української академічної науки в 1918 р. Предмет дослідження – проєкт В. І. Вернадського «Українська академія наук». Показано комплексність цього проєкту, його інноваційні складники, зокрема значне організаційне розширення природознавчих досліджень. Акцентовано на передбаченні в проєкті необхідності організаційних засад досліджень у сфері прикладних наук. Враховано досвід досліджень зазначеного питання в сучасній українській історіографії. Водночаc звернуто увагу на суперечливість поглядів В. І. Вернадського щодо національного характеру розвитку української науки. Зазначено, що концепція В. І. Вернадського розбудови Української академії наук була значно ширшою і багатшою за концепцію, запропонованою М. С. Грушевським. Розкрито деякі деталі дискусії В. І. Вернадського та М. С. Грушевського з цього приводу. Показано, що проєкт В. І. Вернадського не обмежувався лише створенням такої структури, як Українська академія наук. Він був поширений і на створення таких важливих закладів для функціонування академічних установ, як Національна бібліотека України. Стверджується, що визначальною рисою проєкту В. І. Вернадського «Українська академія наук» була його системність. В основу проєкту покладено органічне поєднанні низки концептуальних чинників її організації, одним з яких є потреба визнання Української академії міжнародною академічною спільнотою.
Еволюція організаційних форм української академічної науки
Authors: Звонкова Г. Л.
Published: January 2024

У статті висвітлено та проаналізовано еволюцію основних форм організації науки з момеснттвуорення Академії наук в Україні. Завдяки загальним та спеціально- історичним методам дослідження (хронологічному, порівняльно-історичному, проблемно-хронологічному) наведена спроба відтворити хронологію виникнення основних структур організації науки в Академії Наук України. Проаналізовано зв’язок теоретичної та практичної роботи цих структур. Наведено інформацію про виникнення та діяльність мережі науково-дослідних кафедр, спеціалізованих науково-дослідних інститутів у різних галузях знань. Висвітлено передумови та практична діяльність наукових центрів Академії. Доведено, що вивчення історичного досвіду роботи певних організаційних структур є дуже актуальним питанням на сьогодення.
Life is like a reservoir into which a scientist who is completely devoted to his work plunges
Authors: Poleva Ju. L.
Published: January 2024

The article is devoted to the description of the pages of the life and scientific activity of the outstanding Ukrainian scientist N. I. Zagubizhenko, who made a great contribution to the formation of the theoretical base on the enrichment of natural and artificial water bodies with fodder resources in the conditions of the Steppe zone of Ukraine. Being a student of the doctor of biological sciences, professor P. O. Zhuravel [1,2], who believed that the enrichment of the benthic fauna of the Steppe zone of Ukraine can be carried out by introducing animal organisms that are absent in these reservoirs, which are characterized by wide plasticity and high vitality [9,12,15], Nadezhda Ivanovna Zagubizhenko was engaged in the study of the reconstruction of the benthic fauna of the reservoirs of southeastern Ukraine. In connection with the instability of the fodder base of water bodies in the Steppe zone of Ukraine, the question of the introduction of representatives of the estuarine fauna, their habituation and inclusion in the food rations of a number of commercial fish was and remains relevant in the current period of time. According to the nature of nutrition, most acclimatizers are biofilters [9], for which there is a sufficient amount of food in the form of detritus, the remains of higher aquatic vegetation, in most reservoirs of the Steppe zone of Ukraine. The conduct and substantiation of these research works were of a positive nature and have a significant contribution to the scientific base, theory, and practice of enriching water bodies with fodder resources and preserving the environment. The quality of water at all times has been and is one of the main indicators of the standard of living, therefore, all developed societies make every effort to provide the population and economy with a sufficient amount of water of a quality that is adequate to the requirements of the consumer. Most of the water comes from natural sources – rivers, lakes, reservoirs, the water quality of which must not only be assessed, but also predicted. Two main components are responsible for the quality of water in nature – the catchment basin and the ecological system of the water body [6, p. 36]. Each of them is located in certain conditions of geography and climate, characteristic of the region under study, in our research – the Steppe zone of Ukraine.
Orientação Educacional: espaço-tempo de escuta e práticas evangelizadoras
Authors: Crestani Alfredo
Published: January 2024

O autor, em sua extrema sensibilidade e perspicácia, não esqueceu nenhum detalhe sobre o profissional da Orientação Educacional e sobre o espaço evangelizador que ele ocupa nas escolas maristas. Em um vasto cardápio, permite-nos saborear os encantos dessa profissão recheada de sabores desse universo plural. Desse modo, é importante mencionar quão significativas são a presença e a participação do Orientador nas ações educativas. Ir. Alfredo Crestani abdicou de ser luz e foco para dar luz e voz a colegas que atuam em colégios maristas e assim diversificar narrativas das experiências profissionais, reafirmando a importância do Orientador na educação, diante de uma sociedade tão exigente. O leitor certamente encontrará, em cada página, a centralidade da pessoa humana, o cuidado e a preocupação com a correção de rumos.
Relato de Pesquisa: Uma Breve Passagem sobre as Relações entre História, Imprensa e a Assembleia Constituinte de 1946
Authors: do Canto Casagrande Giovane
Published: January 2024

A presente pesquisa foi pensada e teve seu início ainda no ano de 2018, a partir dos debates e discussões que ocorreram no grupo de estudos (GE) de História e Imprensa da Pontifícia Universidade Católica do Rio Grande do Sul. Foi nesse contexto que conheci a Profa. Dra. Mônica Karawejczyk. E assim, após quase um ano de participação como ouvinte, recebi o convite para participar de um projeto de iniciação científica (IC) com a professora que também, à época, era uma das coordenadoras do GE.
Análise de Conteúdo na Pesquisa Histórica: Aplicação sobre Fontes da Grande Imprensa
Authors: Costa Juliani Regina Thiago
Published: January 2024

A demonstração da metodologia e dos procedimentos metodológicos na análise tem sido, cada vez mais, lugar incontornável para o entendimento dos resultados de pesquisa e, por consequência, para o avanço das ciências e das mais diversas áreas do conhecimento. Fenômeno esse que se estende ao domínio das humanidades, no qual disciplinas como História tem afiançado sua qualidade de compreensão sobre o passado e sua legitimidade científica por meio da escolha e do rigor metodológicos. Sendo assim, aqui voltarei minha reflexão à análise de conteúdo2, uma técnica de investigação qualitativa, prestes a completar cem anos e popular em múltiplos domínios de pesquisa, incluindo os estudos históricos sobre comunicação.
Enterprises of Defense, Republican, Local and Cooperative Industry, Transport and Communication of the Kazakh SSR during the Great Patriotic War
Authors: Akkuzinov Asset K.
Published: January 2024

Introduction. The purpose of the article is to analyze the activities of defense, republican, local and cooperative industry, transport and communications of the Kazakh SSR during the Great Patriotic War, aimed at the production of military products, weapons, various types of ammunition for the Red Army and Navy. The relevance of the study was determined by the need to identify the performance of the enterprises of the studied areas of industry in Kazakhstan during the Great Patriotic War, which contributed to the build-up of the combat potential of the Red Army and its comprehensive support.

Materials and Methods. The source base of the work was made up by the works of Soviet, Kazakh and Russian authors, data of the Archive of the President of the Republic of Kazakhstan, dedicated to the period of the Great Patriotic War. The author used the method of source study to solve the scientific problem.

Results. The peculiarities of technological production of products by the enterprises of defense and local industry of the republic are given, the main factors of growth of their indicators are established.

Discussion and Conclusions. It is concluded that the efficiency of defense enterprises, republican, local and cooperative industry, transport and communications of the Kazakh SSR, the work of workers of the rear of the republic in 1941–1945 became a significant contribution to the Victory of the USSR in the Great Patriotic War.
Access Control System Analysis in Heterogeneous Big Data Management Systems
Authors: Poltavtseva Maria Anatolyevna , Kalinin Maxim Olegovych
Published: January 2024

Big data management systems are in demand today in practically all industries, and they are also the foundation for artificial intelligence training. The use of heterogeneous poly-stores in big data systems has led to the fact that tools within the same system have different data granularity and access control models. Harmonization of such components by the security administrator and implementation of common access-policy is now done manually. This leads to an increasing number of customization vulnerabilities, which in turn serves as a frequent cause of data leaks. Analysis of works in the area of automation and analysis of access control in big data systems shows the lack of automation solutions for poly-store based systems. This paper poses the problem of automating the analysis of access control analysis in big data management systems. The authors formulate the main contradiction, which consists, on the one hand, in the requirement of scalability and flexibility of access control, and on the other hand – in the growth of the burden on the security administrator, aggravated by the use of different data models and access control in the system components. To solve this problem, we propose a new automated method for analyzing security policies based on a graph model of data processing, which reduces the number of possible vulnerabilities resulting from incorrect administration of big data systems. The proposed method uses the data life cycle model of the system, current settings and the desired security policy. The use of two-pass analysis (from data sources to recipients and back) allows to solve two tasks: analyzing the access control system for possible vulnerabilities and checking compliance with correctness of business logic. The paper gives an example of analysis of security policies of the big data management system using the developed software prototype and analyzes the obtained results.
Numerical Simulation of Particulate Matter Transport in the Atmospheric Urban Boundary Layer Using Lagrangian Approach: Physical Problems and Parallel Implementation
Authors: Varentsov Alexander Ivanovich , Imeev Ochir Anatolievich , Glazunov Andrey Vasilievich , Mortikov Evgeniy Valerievich , Stepanenko Viktor Mihajlovich
Published: January 2024

This paper presents the results of the development of a numerical model of the Lagrangian particle transport and the application of parallel computation methods to increase the efficiency of the software implementation of the model. The model is a software package allowing calculations of transport and deposition of aerosol particles taking into account the properties of particles and input data describing atmospheric conditions and the underlying surface geometry. The dynamic core, physical parameterizations, numerical implementation, and algorithm of the model are described. Initially, the model has been used for computationally low-intensive problems. In this paper, given the need to use the model in computationally intensive problems, we conduct optimization of the sequential software implementation of the model, as well as creation of software implementations of the model with the use of parallel computing technologies OpenMP, MPI, CUDA. The results of testing of different implementations of the model show that optimization of the most computationally complex blocks in the sequential version of the model can reduce the execution time by 27%, at the same time the use of parallel computing technologies allows to achieve acceleration by several orders of magnitude. The use of OpenMP in dynamic block of the model resulted in acceleration of block up to 4 times, the use of MPI – up to 8 times, the use of CUDA – up to 16 times, all other conditions being equal. Recommendations on the choice of parallel computing technology depending on the properties of the computing system are proposed.
Management of Sustainable Development and Its Impact on the Performance of Government Institutions in Iraq
Authors: Nursaid Nursaid , Ahmed Fareed Hussein , Makrina Tatyana Antolyevna
Published: January 2024

The research aims to influence the management of sustainable development represented in (the environmental dimension, the economic dimension, the social dimension, and the technological dimension) in government institutions represented (planning, organization, direction, and control) in the College of Administration and Economics, where the research sample was chosen to include a number of The staff of the college, has developed (90) questionnaires for both genders, returned (86) subject to statistical work, where the results showed a positive impact of sustainable development management in government institutions. Significant relationship between the technological dimension and the institution's performance. The results of the research show that there is a relationship between the economic dimension, the social dimension,  the environmental dimension, and the performance of the institution and the institution's performance.
Development and Validation of Cyberbullying Measurement Instrument: A Mixed Method Approach
Authors: Supriatna Ecep , Hanurawan Fattah , Eva Nur , Rahmawati Hetti
Published: January 2024

This research is motivated by the increasing increase in cyber bullying and the negative impacts it causes. This research aims to develop a cyberbullying measurement instrument using a mixed methods approach involving three stages. Theme exploration stage, namely the qualitative stage with open questionnaire data collection techniques to explore themes surrounding Cyberbullying. At this stage the data analysis technique applied is open coding (65 participants). The testing stage is the content validity stage where the instrument is assessed by experts using the Aiken formula. This stage also includes factor analysis with an exploratory factor analysis (EFA) approach which helps identify the factorial structure underlying the instrument, relationships between items, and grouping items based on dimensions (270 participants). Scale validation stage where at this stage confirmatory factor analysis (CFA) was carried out to test and validate the factorial model identified through EFA (789 Participants). Sampling technique uses convenience sampling technique. The results of the research show that based on the CFA test, the cyber bullying scale showed that all items had loading factor values >0.5 and construct reliability >0.7, as well as AVE results >0.5, so that all the items used were forming factors of the latent variable. The items used are valid and reliable items so they can be relied upon as research measuring tools. Reliable Cyberbullying measurement instruments can more precisely identify cyberbullying behavior and thus can assist in a better understanding of this phenomenon, so that prevention and intervention efforts can be targeted more effectively.
Incorporating Social Values Toward Islamic Education in Multicultural Society
Authors: Mulyana Rohmat
Published: January 2024

Enhancing students' understanding of social values in a multicultural society is crucial within Islamic education. This research employs a mixed-method approach, combining qualitative and quantitative analyses, to explore factors supporting incorporating social values into curriculums and teaching strategies. Lessons in Islamic studies and social studies are delivered experientially and contextually, influencing students' social attitudes toward diversity, including tolerance, patriotism, respect, and sympathy. The findings highlight the comprehensive impact of this integrated approach on shaping students' perspectives.
Work-related stress and quality of life in nurses during the Covid-19 pandemic
Authors:   Universidad del Sinú, Montería, Colombia., Díaz Hernández María Angélica , Gorrostola Camargo Angie Paola ,   IPS Cuidado seguro en casa, Montería, Colombia., Mendoza Romero Darío ,   Fundación universitaria del Areandina, Bogotá, Colombia.
Published: January 2024

Introduction: Work-related stress is the physical and emotional manifestation triggered by an imbalance in coping with perceived demands. One of the workers most affected by work-related stress is the nursing staff, a situation that was exacerbated during the COVID-19 pandemic and could affect their quality of life. Objective: To evaluate the connection between quality of life and work-related stress in nurses during the COVID-19 pandemic. Materials and Methods: Analytical, cross-sectional study, with a quantitative approach. Descriptive statistics and multiple linear regression analysis were used for the present study. Results: A negative correlation was obtained between quality of life and stress level (r = -0,438, p < 0,01), and being a professional nurse was related to higher stress levels. On the other hand, being 31 years or older and having more than 12 months of work experience were associated with a higher quality of life score, while being female, single, divorced, or widowed and having higher acute stress scores indicated a significantly worse quality of life. Discussion: Acute stress negatively affects the quality of life of nurses during the COVID-19 pandemic and this differs significantly according to age, sex, marital status, and work experience. Conclusion: It is recommended that the health sector authorities design policies that guarantee strategies to improve the mental health of nursing personnel, as well as to guarantee fair and dignified treatment.
Breast Milk Jaundice
Authors: Belyaeva Irina A. , Bombardirova Elena P. , Kurnatovskaya Elena O.
Published: January 2024

The results of modern studies on breast milk jaundice pathogenesis, that is common form of neonatal jaundice, are presented. The major risk factors and diagnostic methods (excluding other forms of jaundice syndrome at recurrent and lingering jaundice in newborns) were defined. The main therapy approaches for breast milk jaundice were presented. Issues of phototherapy indications were discussed. The feasibility of maintaining breastfeeding in case of breast milk jaundice development was proved. This condition requires the attention of pediatricians despite the relatively favorable course and outcomes. The need to continue studies on pathogenetic therapy of such patients was noted.
Supplemental Feeding Implementation: Window of Opportunities for the Intestinal Microbiota Development and Immune Responses Modulation
Authors: Belyaeva Irina A. , Namazova-Baranova Leyla S. , Bombardirova Elena P. , Shukenbayeva Regina A. , Turti Tatyana V.
Published: January 2024

This review summarizes stages of intestinal microbiota development in infant and immune responses modulation associated to these stages. The leading role of breastfeeding in the optimal microbiota and associated immune responses development during the first half of child’s life is presented. The biological feasibility of supplemental feeding implementation at the second window of opportunity (4–6 months) is justified, as well as role of supplementation products (including cereal) in adult microbiota development.
Role of Calcineurin Inhibitors in the Management of Atopic Dermatitis in Children
Authors: Efendieva Kamilla E. , Namazova-Baranova Leyla S. , Levina Juliya G. , Kalugina Vera G. , Alekseeva Anna A. , Vishneva Elena A. , Volkov Konstantin S.
Published: January 2024

Atopic dermatitis (AD) is a widespread chronic inflammatory skin disease that has a significant impact on various aspects of patient's life. This review presents modern view on AD pathophysiology, its correlation with other concomitant diseases, and covers practical aspects of external anti-inflammatory therapy implementation. The analysis of clinical studies has shown the significant role of calcineurin inhibitors in the effective treatment of AD in children from its first manifestations at early age.
Combination Treatment for Severe Forms of Mucopolysaccharidosis, Type I (Hurler Syndrome): Case Report
Authors: Vashakmadze Nato V. , Zhurkova Natalia V. , Babaykina Marina A. , Dobrotok Albina V. , Gordeeva Olga B. , Namazova-Baranova Leyla S.
Published: January 2024

Background. Hurler syndrome (mucopolysaccharidosis, type I) is a rare hereditary disease with chronic course. The main methods for Hurler syndrome management are hematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy (ERT). In recent years, combination treatment (ERT administration both before and after HSCT) has shown its efficacy in case of disease progression. Clinical case description. The presented clinical cases demonstrate the efficacy of ERT administration in patients with Hurler syndrome after HSCT: in the first clinical case due to the decrease in alpha-iduronidase activity 2 years after HSCT, in the second clinical case due to the aggravation of the patient's condition (cardiovascular and respiratory systems, hepatomegaly, although the level of enzyme and glycosaminoglycans in the patient's urine remained within normal values). Conclusion. Combination treatment including ERT not only before HSCT, but also in case of clinical state worsening after HSCT, plays significant role in stabilizing the patient's condition, preventing rapid progression of symptoms and development of life-threatening complications (especially cardiovascular ones).
Analysis of the Treatment Efficacy in Late Diagnosis of Alport Syndrome in a Child: Clinical Case
Authors: Volgina Svetlana Ya. , Solovyeva Nailya A. , Kulakova Galina A. , Kurmayeva Elena A. , Mukhametdinova Liliya I. , Rashitova Elina L.
Published: January 2024

Background. Alport syndrome is a systemic, hereditary, progressive disease characterized by ultrastructural changes in the glomerular basement membrane caused by pathogenic variants of type IV collagen genes. The use of angiotensin-converting enzyme inhibitors (ACEI) for nephroprotection is effective at the microhematuria and/or albuminuria stage. Treatment tactics in case of nephrotic syndrome development in such patients remains the subject of discussion. Clinical case description. The patient was diagnosed with proteinuria at the neonatal period and hematuria at the age of one month. The hereditary nephritis was diagnosed at the age of 6 years; the ACEI was administered, however, the proteinuria continued to increase. The diagnosis was confirmed at the age of 8.5 years via the puncture nephrobiopsy: collagenopathy, type IV, focal segmental glomerular sclerosis. Moreover, chronic bilateral sensorineural hearing loss and bilateral myopic astigmatism were diagnosed. Ciclosporin A (125 mg/day) was additionally prescribed. The increase in the cystatin C, urea, uric acid, cholesterol levels in blood was mentioned after 14 months of treatment. These parameters decreased after reducing cyclosporine A dose to 100 mg/day, however, proteinuria has increased. Angiotensin II receptor blocker (candesartan 8 mg/day) was prescribed to enhance nephroprotective therapy at the age of 10 years 2 months. Another increase of the immunodepressant dose was performed at the age of 11, it led to decrease in the estimated glomerular filtration rate and increase of creatinine, cystatin C, urea, cholesterol, uric acid, and potassium levels in the blood. These changes were considered as cyclosporine-dependent. The dose of cyclosporine A was reduced to 125 mg/day, and to 100 mg/day from the age of 14. There was no progression of chronic kidney disease at the follow-up at the age of 15.5 years. Conclusion. Nephroprotective treatment of a child with Alport syndrome initiated after the development of nephrotic syndrome did not stop the chronic kidney disease progression. Whereas relatively high doses of ciclosporin A have reduced proteinuria but led to nephrotoxicity and cyclosporin dependence.
Service-Oriented State in the Conditions of Digital Transformations
Authors:   State University of Information and Communication Technologies, Petkun Svetlana
Published: January 2024

The article examines the essence of the concept of a “service-oriented state” in the context of digitalization in Western Europe and identifies the peculiarities of its implementation in Ukraine. The concept of a service-oriented state involves a change in the approach to public sector management and transformation of the principles of relations between public authorities and citizens. The service approach in public administration primarily involves the introduction of information management technologies aimed at improving the quality of public services, enhancing social protection of the population and, ultimately, creating effective social security. The priority task of the state is to create conditions for self-realization of individuals, ensure their individual freedom and rights, and provide public services that would meet the needs of citizens. Modern digital technologies are significantly changing our lives, namely the way we produce products and services, methods and forms of education, and affect the social structure of society, the economy, politics, and the development of socio-cultural institutions. Ukraine’s priority task is to create a service-oriented state in which digital technologies would create conditions for self-realization of individuals, their individual freedom and rights, provision of quality public services, and effective social security.
The Issue of Independence in Opinion Polls in Wales in 2017–2023
Authors:   University of Szczecin, Toszek Bartłomiej H.
Published: January 2024

This study presents and analyzes the results of public opinion surveys conducted in Wales in 2017–2023 regarding the political future of the region. Using quantitative, comparative and systemic methods, the political solutions proposed by the Welsh were identified. The aim of the study is to answer the question whether current centrifugal tendencies may lead to Wales gaining independence in the foreseeable future.