bluuebunny/crossref_metadata_2025 huggingface dataset:
University Students, Academic Structures and the Processes of Integration
Authors: Ige B. O. , Naidoo K. L.
Published: January 2023

This special issue on Finding a Place to Belong: University Students, Academic Structures and the Processes of Integration contains nine papers on opportunities of belonging and highlights the cultivation of belonging as a fundamental for addressing inequality and inequity in a linguistically and culturally diverse higher education context. Here, belonging challenges the dominant university ideology, which can elude the marginalised or underserved student and staff groups of learning communities. The combination of individual/group agency and identity negotiation for developing and implementing enablers of belonging reveals the challenges and complexity of deconstructing belonging. The papers focus on the barriers and opportunities of belonging and the interaction of agency and enablers of belonging, such as equitable vision, policy, programmes and commitment, as a product of belonging. Keywords: Deconstructing Belonging Opportunities Barriers Transformation Multiple Identities Multiple Belongings
Determination of Treatment Efficacy of Lung Cancer using Diffusion-Weighted Whole Body Imaging with Background Suppression（DWIBS）Quantification Software (BD Score)
Authors: Yamamoto Yasuhiro , Numa Tetsuya , Matsuda Kaori , Okazaki Yoshio , Watanabe Seiichirou , Kimoto Shin , Hiraki Takao , Takahara Taro
Published: January 2023

Chemotherapy for lung cancer has made remarkable progress, and its selection has been subdivided by genetic analysis. Although response evaluation criteria in solid tumors (RECIST) is a simple and highly objective evaluation method, it has been pointed out that it has the disadvantage of not being able to accurately evaluate the therapeutic effect of molecularly targeted drugs and immune checkpoint inhibitors. The purpose of this study is to determine whether quantitative evaluation of DWIBS is useful in determining the effectiveness of treatment for lung cancer. There were 31 patients with lung cancer and 56 patterns were obtained. First, the determination of treatment effect (PD, SD, PR) based on RECIST was performed on CT. Second, tDV and ADC (median) were measured using BD score from DWI images taken at the same time, and the rate of change was calculated. Then, we compared and examined the correlation between RECIST and the rate of change in tDV. There were correlations between RECIST and the rate of change in tDV in PD and PR cases respectively. Compared RECIST on CT, DWIBS using BD score would be more accurate for response evaluation of treatment. There was a tendency that tDV decreased with increasing ADC values, but some of the cases had a dissociated response with increasing ADC values and increasing tDV. Thus, since the color display of ADC values allows us to infer their contents, it would be useful for the evaluation of cases such as dissociated response and pseudoprogression, which are suspected to be atypical responses that are difficult to evaluate with RECIST and other methods.
Too Committed to Switch off – Capturing and Organizing the Full Range of Work-Related Rumination from Detachment to Overcommitment
Authors: Weigelt Oliver , Seidel J. Charlotte , Erber Lucy , Wendsche Johannes , Varol Yasemin Z. , Weiher Gerald M. , Gierer Petra , Sciannimanica Claudia , Janzen Richard , Syrek Christine J.
Published: January 2023

Work-related thoughts in off-job time have been studied extensively in occupational health psychology and related fields. We provide a focused review of research on overcommitment – a component within the effort-reward imbalance model – and aim to connect this line of research to the most commonly studied aspects of work-related rumination. Drawing on this integrative review, we analyze survey data on ten facets of work-related rumination, namely (1) overcommitment, (2) psychological detachment, (3) affective rumination, (4) problem-solving pondering, (5) positive work reflection, (6) negative work reflection, (7) distraction, (8) cognitive irritation, (9) emotional irritation, and (10) inability to recover. First, we leverage exploratory factor analysis to self-report survey data from 357 employees to calibrate overcommitment items and to position overcommitment within the nomological net of work-related rumination constructs. Second, we leverage confirmatory factor analysis to self-report survey data from 388 employees to provide a more specific test of uniqueness vs. overlap among these constructs. Third, we apply relative weight analysis to quantify the unique criterion-related validity of each work-related rumination facet regarding (1) physical fatigue, (2) cognitive fatigue, (3) emotional fatigue, (4) burnout, (5) psychosomatic complaints, and (6) satisfaction with life. Our results suggest that several measures of work-related rumination (e.g., overcommitment and cognitive irritation) can be used interchangeably. Emotional irritation and affective rumination emerge as the strongest unique predictors of fatigue, burnout, psychosomatic complaints, and satisfaction with life. Our study assists researchers in making informed decisions on selecting scales for their research and paves the way for integrating research on effort-reward imbalance and work-related rumination.
Распространение вариантов вируса SARS-COV-2, вызывающих озабоченность (VOC) на основе количества их геномов, депонированных в базу данных GISAID за неделю с 31.12.2022 г. по 06.01.2023 г.
Authors: Дмитриева Людмила , Краснов Ярослав , Чумачкова Елена , Осина Наталья , Зимирова Анастасия , Иванова Александра , Карнаухов Игорь , Караваева Татьяна , Шербакова Светлана , Кутырев Владимир
Published: January 2023

В обзоре представлена информация по циркулирующим в настоящее время вариантам вируса SARS-COV-2 вызывающих озабоченность (VOC), геномные последовательности которых размещены в международной базе данных GISAID за неделю с 31 декабря 2022 г. по 6 января 2023 г.
Designing and Building a Web-Based Book Sales and Tenancy Platform
Authors: Iswayudi Candra , Kautsar Irwan Alnarus , Suprianto Suprianto
Published: January 2023

Infrastructure development that continues to increase is one of the conveniences for the community to use the internet, which can access various digital content such as websites, chat, shopping, and others. More than half of the population in Indonesia accesses the internet every day, if it is used to make a product branding, it will be more time efficient and save costs. Books are one of the products that must exist in every generation because they are an important source of information in everyday events. This study aims to create a place for people who want to sell books that can make it easier for buyers or consumers. Utilizing a website that can speed up an activity and save time to sell or find books for sellers and consumers. This research was built using Python as a programming language, Flask Framework as a system framework, sqlite3 as data storage, and bootstrap 5 as a display foundation combined with style changes through CSS (Cascading Style Sheets). Agile development is a method used to develop marketplace platforms. The result of this research is a web-based book rental and tenancy marketplace platform.
Implementación del manual de buenas prácticas ITIL y su relación con la mejora de la calidad de los servicios de TI, en la Minera Chinalco S.A, Lima 2021
Authors:   , Oquendo Noriega Alfredo Manuel
Published: January 2023

Es innegable el valor de ITIL en el uso de las buenas prácticas y el soporte tecnológico. Se basa en la implementación del manual de prácticas especializado en optimizar los servicios de TI. Se compone por varios tipos eBooks que nos explica cómo implementar las mejores prácticas en la gestión de servicios de TI, por lo tanto con lleva que las áreas de TI (Tecnología de la información) a mejorar los tiempos de respuesta y afrontar los avances del mercado empresarial. ITIL representa la innovación de los flujos de trabajos optimizando la forma en que los procesos se ejecutan. En esta investigación basado en la compañía Minera Chinalco se presenta la ausencia de un modelo de mejora. Se basa en el diseño del modelo de mesa de ayuda que mejora en gran medida los servicios de TI de acuerdo con el enfoque ITIL. Primero, se analizó el contexto de la problemática a investigar, que hacía referencia a la omisión del uso de una guía basada en la gestión de servicios. Segundo, se ejecutó una revisión de cada proceso utilizado por parte servicio técnico validando que no tenían con procesos de una manera clara; tampoco contaban con guía de gestión de servicios dando como consecuencia un trabajo poco eficiente. Tercero, por la factibilidad y la disponibilidad de los datos se conversó con representantes de cada área de TI y los asistentes de Helpdesk sobre la importancia de ITIL y las ventajas que se va ganando al implementarlo como guía. De tal manera se logra armar una guía de gestión y atención que beneficiara en el uso correcto de la atención por parte de las diferentes áreas de TI.
Plan de negocio para la elaboración de una aplicación móvil que brinda servicios de contratación de limpieza en los distritos de La Molina, Lince y Miraflores
Authors:   , Pillaca Ccaccya Gabriela Isabeo , Ponce Chanca Benjamin Ederson
Published: January 2023

La presente investigación se ha elaborado en el transcurso de todo el semestre de manera formal, pero se ha podido recopilar datos relevantes de anteriores investigaciones propias de nosotros como autores realizados en anteriores ciclos. En el transcurso de la elaboración de esta investigación hemos podido recolectar datos e información necesaria para realizar el Plan de Negocios respectivo para la elaboración de un aplicativo móvil que brinde servicios de limpieza a hogares de Lima, en los distritos de La Molina, Lince y Miraflores. En el lapso de 2023-2028. Toda nuestra información extraída y recopilada, son datos con vigencia desde el año 2018 en adelante, para poder desarrollar esta investigación. Algunos de los puntos más impactantes de nuestra investigación, referente al perfil de nuestro mercado objetivo, es encontrar que en nuestra población el porcentaje de jóvenes adultos, de 24 años hasta los 40 años, socialmente y laboralmente activos, cada año esta cantidad está incrementando su porcentaje. Según el estilo de vida de nuestra población indica que tienen capacidad de adquisición de nuestro servicio. Por otro lado, el porcentaje de personas que trabajan brindando servicio de limpieza doméstica desean tener mejores oportunidades laborales. Nuestros servicios ofrecidos a los consumidores, se clasifican por planes, donde cada plan presenta una serie de servicios y accesos que el cliente puede escoger según su necesidad. Referente a nuestra estructura organizacional, ahora contamos con los socios de la alta gerencia, que son los autores de la presente investigación, que cubren dos pilares fundamentales respecto a la elaboración del aplicativo móvil, que son el perfil de contabilidad financiera y el perfil de desarrollo de software, por lo que en primera instancia se mantiene una estructura administrativa básica, para gestionar las áreas que se vayan adoptando.
Plan de negocio para la exportación de mantequilla de ajo al mercado mexicano
Authors:   , Figueroa Cáceda Sandra Isabel , Pulcha Hernani Elizabeth Moraima , López Llacta Lucero Teodora
Published: January 2023

Nuestro plan de negocio tiene como fin principal, la exportación de mantequilla de ajo al mercado mexicano, para ello, se fundará una empresa la cual será una Sociedad Anónima Cerrada (SAC) y se ubicará en Lima metropolitana. Iniciaremos con el desarrollo del plan de negocio, dejando claro los objetivos organizacionales, misión y visión. Así mismo, la empresa se acogerá al régimen de las micro y pequeñas empresas (MYPE), el cual tiene muchos beneficios en el mercado. Después trabajaremos en nuestro Plan de Marketing, donde chequearemos la especificación del producto, su clasificación arancelaria, y las tácticas que desarrollaremos para promocionar el producto en el mercado destino (México). Seguiremos con el Plan de Logística en todo el mundo, en el cual explicaremos el desarrollo de Exportación el cual tiene dentro unitarización y cubicaje de la carga. Así mismo, continuaremos con el “Plan de Comercio Internacional” donde desarrollaremos y también se establecerá los medios de pago, INCOTERM y el Régimen de Exportación de productos. Finalmente determinaremos la capacidad de la compañía de acuerdo con nuestras finanzas, el recurso humano, los insumos y la tecnología.
Respuesta del tejido pulpar a la proteína derivada de la matriz del esmalte como agente de regeneración en terapia pulpar vital en dentición decidua. Revisión de literatura
Authors:   , Pinto Huaman Arnold Fermin
Published: January 2023

OBJETIVO: La finalidad de la revisión fue evaluar la respuesta histológica del tejido pulpar a la proteína derivada de la matriz del esmalte en terapia pulpar vital en dentición decidua. según literatura. MÉTODO: Se realizó la búsqueda de la literatura pertinente en bases de datos Pubmed/Meedline, Science Direct de artículos originales con una antigüedad de 10 años como máximo. La búsqueda se hizo utilizando las siguientes palabras clave usando las siguientes combinaciones: (proteína derivada de la matriz del esmalte OR EMD OR Emdogain), AND (recubrimiento pulpar directo OR pulpotomía); (tratamiento pulpar AND dientes deciduos); (pulpotomía OR recubrimiento pulpar directo AND dientes deciduos). Una vez localizados los artículos se seleccionaron los más idóneos para la revisión, para su posterior lectura crítica y análisis. RESULTADOS: La formación de puente de dentina no ha sido completa, la reorganización morfológica se ha manifestado en la proliferación de células pulpares y diferenciación Odontoblástica, la reacción inflamatoria de la pulpa ha sido leve, moderada y severa y se halló presencia de células bacterianas en la pulpa de dientes con recubrimiento pulpar directo y pulpotomía. CONCLUSIÓN: Se encontró respuesta histológica variada del tejido pulpar a la proteína derivada de la matriz del esmalte (Emdogain) en dientes con recubrimiento pulpar directo y pulpotomía.
Identificación de Escherichia coli O157:H7 en cuchillos y ganchos usados para manipulación de carcasas bovinas en dos camales de Lima-2021
Authors:   , Huamaní Arteaga Rocío Alexandra
Published: January 2023

El objetivo fue identificar Escherichia coli O157:H7 en cuchillos y ganchos utilizados para manipulación de carcasas bovinas en mataderos de Lima. Se colectaron 91 muestras en dos camales para bovinos del Valle del Lurín, 56 muestras del camal 1 y 35 muestras del camal 2. Se utilizó el método de hisopo sobre todos los cuchillos y ganchos para movilización de carcasas en riel luego de finalizar la jornada de faenamiento. Posteriormente, fueron cultivadas en agar Mac Conkey, la identificación de la bacteria, se realizó mediante pruebas bioquímicas. Luego, se realizaron pruebas de aglutinación en látex para determinar los serotipos O157 (Oxoid©) y O157:H7 (Remel©). De las 91 muestras se obtuvo el 28.6% (26/91) positivo para E. coli, el 1.1% (1/91) de muestras resultaron positivas para O157 y no se identificó el serotipo O157:H7 en los cuchillos y ganchos analizados, lo que evidencia que la aplicación adecuada y continua de procedimientos sanitarios son esenciales para preservar la inocuidad y calidad de la carne en los mataderos.
Presencia de Campylobacter spp. en dietas tipo BARF (alimento crudo biológicamente apropiado) para perros comercializadas en Lima, Perú
Authors:   , Saldaña Martinez Kiara Lucia
Published: January 2023

El objetivo del presente estudio fue determinar la presencia de Campylobacter spp. en dietas tipo BARF (Alimento crudo biológicamente apropiado) para perros establecidas en Lima, Perú. Se analizaron 10 marcas comerciales de alimento BARF congeladas, cada una de lotes diferentes, procesando 100 muestras en su totalidad. Las muestras fueron seleccionadas al azar y correctamente selladas, fueron transportados y conservados a 4°C de temperatura aproximadamente hasta su procesamiento en el laboratorio. Se utilizó el método de presencia/ausencia ISO 10272-1:2017, donde se generó el aislamiento microbiológico empleando el Caldo Bolton como medio de enriquecimiento y un medio selectivo CCDA, seguido de un segundo medio selectivo Karmalli para Campylobacter. Las colonias sospechosas se resembraron en Agar Sangre para su confirmación. La bacteria Campylobacter spp. fue aislada del 5% + 4.25% (5/100) de las muestras. Si existe Campylobacter spp. en dietas tipo BARF comercializados en Lima, Perú.
Desregulación emocional y dimensiones del perfeccionismo en universitarios de Psicología en tiempos del Covid - 19
Authors:   , Ypanaqué Díaz Pamela Noriko
Published: January 2023

El presente estudio tuvo por objetivo el analizar la relación existente entre la desregulación emocional y las dimensiones del perfeccionismo en universitarios de entidades públicas y privadas de Lima Metropolitana pertenecientes a la carrera de Psicología, en tiempos del Covid-19. Estudio cuantitativo, transversal, de diseño no experimental y correlacional. El muestreo no probabilístico intencional fue representado por 440 estudiantes de Psicología, de 9 instituciones privadas y 2 públicas. Los instrumentos empleados fueron la Escala de Dificultades en la Regulación Emocional (DERS) y la Escala Multidimensional del Perfeccionismo, ambas en su versión adaptada al Perú. Los resultados destacaron correlaciones positivas y significativas entre la desregulación emocional y el perfeccionismo auto orientado y socialmente prescrito. La correlación fue significativa y negativa con el perfeccionismo orientado a los demás. En el nivel comparativo, se encontró diferencias en el centro de estudios, género y personas que recibieron atención en el área de salud mental en los últimos dos años. Los aportes del estudio contribuirán como precedentes para futuras investigaciones y confirmar modelos teóricos, asimismo brindará información relevante para proponer alternativas de corte preventivo respecto a la problemática estudiada.
Resiliencia y compromiso en el equipo de ventas corporativas de una empresa de telecomunicaciones líder en el año 2020
Authors:   , Huarcaya Ortega Karoline Janelí , Tejada Bonilla Frida Luz
Published: January 2023

El presente estudio se realizó para determinar la relación que existe entre la resiliencia y el compromiso en el equipo de ventas corporativas de una empresa de telecomunicaciones líder en el año 2020. Esta investigación tuvo origen descriptivo, definiendo la importancia de cada una de las variables de estudio para luego demostrar la relación aplicando el método tipo correlacional. Se planteó en la hipótesis la posible relación significativa entre la resiliencia y compromiso en los trabajadores del área de ventas para lograr los objetivos trazados por la empresa. Se realizó un trayecto exhaustivo de fuentes bibliográficas que serán los pilares de la investigación las cuales permitieron descubrir tres dimensiones de resiliencia (competencia personal, confianza en sí mismo y la perseverancia) y tres dimensiones de compromiso (identificación, membresía y lealtad), agrupando 18 indicadores como núcleo de estudio. Se elaboró un instrumento de medición cuyo resultado de confiabilidad fue 0.95 para el coeficiente de correlación Rho de Spearman.
Diversidad taxonómica y patrones de diversidad de la flora en los humedales de la costa central del Perú
Authors:   , Gonzales de Paz Sergio Andrés
Published: January 2023

En los últimos años, el interés por estudiar los humedales ha ido en aumento. A pesar de ello, los impactos en estos ecosistemas han persistido, lo que desencadena en el deterioro de los servicios ecosistémicos que proveen. Una forma complementaria de analizar su diversidad es mediante los índices de diversidad taxonómica los cuales nos permiten tener medidas valiosas para su comprensión y conservación. Con el objetivo de evaluar la diversidad taxonómica de la flora vascular (a partir de los índices Δ+ y Λ+) y algunos de sus patrones de diversidad (relacionados con el recambio de especies) en los humedales costeros del Perú, se evaluó la data existente de 109 especies de plantas vasculares distribuidas en ocho humedales costeros de esa región. Los humedales de Santa Rosa, Pantanos de Villa y Carquín, presentaron los valores más altos de Δ+ lo que nos sugiere su conservación a fin de proteger la diversidad filogenética que albergan. La riqueza tuvo correlación con Δ+ (r = 0.931; p<0.05) y con Λ+ (r = -0.878; p < 0.05) y se obtuvo un modelo lineal confiable de Δ+ en función de la riqueza (R2 = 0.86); su uso, nos permitiría simplificar el cálculo de la diversidad taxonómica para las plantas vasculares de esta región. No se encontraron diferencias para los valores de Δ+ entre humedales protegidos y no protegidos (t = 0.96; p > 0.05) y no se halló correlación entre la distancia entre humedales y la diversidad beta (p>0.05); sumado a los resultados anteriores, esto nos sugiere proponer medidas para proteger estos humedales como un corredor costero que incluya humedales no protegidos en la actualidad.
Impacto del comercio electrónico en la gestión de ventas en el emporio comercial de Gamarra (Lima-Perú), 2021
Authors:   , Malpartida Maiz Oralea , Roman Cordova Vitian Sugey
Published: January 2023

En el mundo (y sobre todo en el Perú), actualmente el comercio electrónico se encuentra en constante crecimiento y adopción por parte de los empresarios, debido al cambio abrupto que las empresas han tenido que enfrentar a raíz de la pandemia mundial ocasionada por la Covid-19 para poder gestionar adecuadamente sus ventas. El propósito principal de esta investigación fue determinar el impacto del comercio electrónico en la gestión de ventas en el Emporio Comercial de Gamarra (Lima-Perú) durante el 2021. Cada una de las variables del estudio fue subdividida en tres dimensiones para una mejor comprensión; por ejemplo, la variable comercio electrónico se subdividió en canal de ventas, publicidad digital y sistemas de información; mientras que, por otra parte, la variable gestión de ventas fue desglosada en atención al cliente, satisfacción del cliente y distribución. Metodológicamente, la investigación se desarrolló bajo el enfoque cuantitativo, alcance explicativo y utilizó el diseño no experimental transeccional correlacional-causal; los participantes fueron 100 microempresarios de la zona comercial objeto de estudio, específicamente vinculados a empresas formales que hacen uso del comercio electrónico, a los cuales se les administró un cuestionario de 18 ítems con alternativas de valoración bajo la forma de la escala de Likert. Luego del procesamiento y análisis de la información, se constató la existencia de un impacto significativo entre el comercio electrónico y la gestión de ventas (p < .05), debido a que luego de usar la regresión lineal se obtuvo un coeficiente de prueba de 0.752.
Influencia de la ansiedad en el aprendizaje del idioma inglés como lengua extranjera en estudiantes de educación superior
Authors:   , Adrianzén Segovia Cyntia Sofía
Published: January 2023

El objetivo que la investigación se propuso fue conocer la relación de la ansiedad y el aprendizaje del idioma inglés en alumnos de una institución educativa superior de Lima. Se consideró como muestra a 37 alumnos. Las variables fueron medidas mediante los instrumentos The Foreign Language Classroom Anxiety Scale y speaking para la ansiedad y el aprendizaje de inglés respectivamente. Se observó que el nivel de ansiedad de los estudiantes era medio y que el componente principal era la ansiedad frente las evaluaciones. Se concluyó que entre la ansiedad y el aprendizaje de inglés hay una significativa relación pues se obtuvo una significancia de 0,000 y un Rho de Spearman = -0,608.
Practical Closed-Loop Reservoir Management Using Deep Reinforcement Learning
Authors: Nasir Yusuf , Durlofsky Louis J.
Published: January 2023

Traditional closed-loop reservoir management (CLRM) entails the repeated application of history matching (based on newly observed data) followed by optimization of well settings. Existing treatments can provide well settings that fluctuate substantially between control steps, which may not be acceptable in practice. Another concern is that the project life (i.e., the time frame for the optimization) is often specified somewhat arbitrarily. In this work, we incorporate treatments for these important issues into a recently developed control-policy-based CLRM framework. This framework uses deep reinforcement learning (DRL) to train control policies that directly map observed well data to optimal well settings. Here, we introduce a procedure in which we train control policies, using DRL, to find optimal well bottomhole pressures (BHPs) for prescribed relative changes between control steps, with the project life also treated as an optimization variable. The goal of the optimizations is to maximize net present value (NPV), with project life determined such that a minimum acceptable rate of return (MARR) is achieved. We apply the framework to waterflooding cases involving 2D and 3D geological models. In the 3D case, realizations are drawn from multiple geological scenarios. Solutions from the control-policy approach are shown to be comparable, in terms of NPV, to those from deterministic realization-by-realization optimization and clearly superior to results from robust optimization over prior models. These observations hold for a range of specified MARR and relative-change values. The optimal well settings provided by the control policy display gradual ramping, consistent with operational requirements.
Experiences and perceptions of men following breast cancer diagnosis: A meta-synthesis
Authors: Abboah-Offei Mary , Bayuo Jonathan , Salifu Yakubu , Afolabi Oladayo , Akudjedu Theophilus
Published: January 2023

Background

Men with breast cancer (MBC) experience unique physical and emotional challenges. However, a thorough understanding of these experiences including the psychosocial effects and supportive care needs have received less attention. In some settings, MBCs experience stigma within the healthcare system and their care needs are not prioritised. This influences the level of professional support offered, consequently worsening their health and well-being outcomes. This review explored the variabilities in the experiences and treatment outcomes of MBCs across different demographic contexts.

Methods

All primary study designs including qualitative, quantitative and mixed methods studies that reported on the experiences, treatment approaches and outcomes of MBC were included in this systematic review. Six databases (Embase, Medline, PsycINFO, Global Health, CINAHL and Web of Science were searched for articles from database inception to 2021. A results-based convergence synthesis was used for data analysis and reported using PRISMA guidelines.

Results

38 studies met the inclusion and exclusion criteria. Our findings relating to the experiences and treatment outcomes of MBC are broadly themed into three parts. Theme 1 - Navigating through a threat to masculinity: describes how males experienced the illness reflecting on detection, diagnosis, coming to terms with breast cancer, and disclosure. Theme 2- Navigating through treatment: captures the experiences of undergoing breast cancer treatment/ management following their diagnosis. Theme 3 - Coping and support systems: describes how MBCs coped with the disease, treatment process, aftercare/rehabilitative care, and the available support structures.

Conclusions

Men experience a myriad of issues following a breast cancer diagnosis, especially with their masculinity. Awareness creation efforts of MBC among the general public as well as healthcare practitioners are urgently required. Considerations for training, education and development of specialised guidelines for healthcare practitioners on MBC would provide the necessary knowledge and skills to enhance their practice through the adoption of person-centred and male-specific care strategies. Professional care intervention and support for MBC should not end after the diagnosis phase but should extend to the entire treatment continuum and aftercare.
PROSPERO Registration No. CRD42021228778
Combined novel soft computing and ensemble technique analysis based on Review Spam Detection
Authors: Amin Irtiqa , Dubey Mithilesh Kumar , Yaseen Syed Mufassir , Shah Mohd Asif
Published: January 2023

In the era of steadily expanding e-commerce, people prefer to purchase things and commodities online which helps them to save time and efforts. The huge quantity of these online purchase decisions is influenced by the suggestions of previous purchasers thereby increasing the spam content on the websites. As of the prevalence of spam content on social media is rapidly expanding, the subscribers receive a large number of junk information such as malevolent links, bogus accounts, fraud news and reviews via social networking sites and are unable to differentiate between spam and legitimate texts thereby making spam recognition vital. This research paper discusses about the novel soft computing and ensemble machine learning techniques and challenges based on detection of these review spams. It uses the datasets from different hotels and extracted its reviews, creation of novel model to analyze the problem, thus resulting in overall performance of model approximately equal to 85% of accuracy.
Bioinformatics analysis of programmed cell death in spinal cord injury
Authors: He Xuegang , Deng Bo , Ma Miao , Wang Kerao , Wang Yonggang , Kang Xuewen
Published: January 2023

STUDY DESIGN:Explanatory or mechanistic studiesOBJECTIVES:Programmed cell death (PCD) in the development of spinal cord injury (SCI) is complicated, including apoptosis, necroptosis, pyroptosis, ferroptosis, cuproptosis and autophagy. It is necessary to make clear the expression levels of PCD and potential molecular targets after SCI for formulating relevant treatment strategies.SETTING:Key Laboratory of Orthopedics Disease of Gansu Province, Lanzhou, Gansu，ChinaMETHODS:Download the rats SCI expression matrix GSE45006, ssGSEA method was used to analyze the PCD in SCI. Then the related differentially expressed genes (DEGs) were identified, and the gene ontology (GO) and pathway analysis, protein-protein interaction (PPI) network construction and hub genes were identified. Finally, the correlation between hub genes and PCD was analyzed.RESULTS:Apoptosis, necroptosis, pyroptosis, ferroptosis and autophagy increased significantly in the acute SCI, and then decreased gradually in the subacute and chronic stages; cuproptosis in acute SCI decreased significantly, and then gradually increased. In addition, we also screened 116 DEGs during the development of SCI. GO and pathway analysis showed that DEGs was related to mitosis and cell cycle. The identified hub genes are closely related to cell apoptosis, necroptosis, pyroptosis, ferroptosis after injury and autophagyCONCLUSIONS:PCD occurs differently in different stages after SCI. To inhibit apoptosis, necroptosis, pyroptosis, ferroptosis after injury and induce autophagy may be the therapeutic strategy. In addition, intervention therapy based on related hub genes may be the therapeutic target of SCI.
WITHDRAWN: The contribution of diminishing river sand loads to beach erosion worldwide
Authors: Graffin Marcan , Regard Vincent , Almar Rafael , Anthony Edward , Ranasighe Roshanka , CARRETIER Sebastien , Maffre Pierre
Published: January 2023

The erosion of sandy beaches can have a profound impact on human activities and ecosystems, especially on developed coasts. The scientific community has, to date, primarily focused on the potential impact of sea-level rise on sandy beaches. While being abundantly recognized at local to regional scales in numerous studies over the last two decades, the contribution of diminishing fluvial sediment supply to sandy beach erosion at the global scale is still to be investigated. Here, we present the first global sand pathway model from land to sea. We show that recent sandy beach evolution trends worldwide are strongly controlled by fluvial sand input to the ocean, and that there is a global convergence of sand at the Equator due to wave-induced longshore transport. The reduction of sand supplies to beaches caused by river-basin changes such as dam constriction has a profound effect on beach stability. Our analysis demonstrates the massive impact of the thousands of river dams on beach erosion worldwide.
Where do you stand? An exploration of perspectives toward feet, foot health, and footwear using innovative digital methods
Authors: Skidmore Sue , Prior Yeliz , Nester Christopher , Bird Sam , Vasilica Cristina
Published: January 2023

Background The cost of losing foot health is significant to the person, healthcare systems, and economy, with diabetes related foot health issues alone costing over £1 billion annually in the UK. Yet many foot health problems are preventable through alternative health behaviour. It is therefore important to understand how feet, foot health and footwear are conceptualised to gain understanding about how these might influence foot health behaviour and inform health messages that seek to protect or improve foot health through altered health behaviour. This research seeks to explore attitudes and beliefs and identify phenomena that may act as barriers or motivators to the proactive self-management of foot health, Methods Public conversations involving 2,699 expressions related to feet, footwear or foot health on Facebook, Twitter, and Instagram were extracted. Conversations on Facebook and Twitter were scraped with NVivo’s NCapture plugin whereby data is extracted and downloaded to NVivo. Extracted files were uploaded to the Big Content Machine (software developed at the University of Salford) which facilitated the search for keywords ‘foot’, ‘feet’, ‘footwear’, ‘shoe’, and ‘shoes’. Instagram was scraped by hand. Data was analysed using a Thematic Analysis approach. Results Three themes were identified; 1) connections and disconnections derived from social and cultural constructs, 2) phenomena beyond attitudes and beliefs that relate to symbolic representations and the impact when foot health is lost, and 3) phenomena relating to SoMe as a conduit for the exploration of attitudes and beliefs. Conclusions This novel research exemplifies complex and sometimes incongruous perspectives about feet including their value for what they facilitate, contrasted with negative feelings about the negative impact that can have aesthetically when feet work hard. Sometimes feet were devalued, with expressions of disgust, disconnection, and ridicule. The importance of contextual, social, and cultural phenomena with implications for optimising foot health messages. Knowledge gaps including factors related to children’s foot health and development, and how to treat foot health problems. The power of communities with shared experience to influence decisions, theories, and behaviour about foot health was also revealed. While people do talk about feet in some social contexts, it is not always in a way that promotes overt, positive foot health behaviour. Finally, this research demonstrates the benefit of exploring perspectives in uncontrived settings and illuminates the potential utility of SoMe as a vehicle to promote foot health self-management behaviour that is responsive to the social and demographic variances of engagers who inhabit those spaces.
Sub-nanometric high entropy alloy cluster: hydrogen spillover-driven synthesis on CeO2 and structural reversibility
Authors: Hashimoto Naoki , Mori Kohsuke , Matsuzaki Shuichiro , Iwama Kazuki , Kamiuchi Naoto , Yoshida Hideto , Yamashita Hiromi
Published: January 2023

High-entropy alloy (HEA) nanoparticles (NPs) have attracted significant attention as promising catalysts, as a consequence of the various unique synergistic effects originating from the nanometer-scale, near-equimolar mixing of five or more components to produce single-phase solid solutions. However, the study of sub-nanometer HEA clusters having sizes of less than 1 nm remains incomplete despite the possibility of novel functions related to borderline molecular states with discrete quantum energy levels. The present work demonstrates the synthesis of CeO2 nanorods (CeO2-NRs) on which sub-nanometer CoNiCuZnPd HEA clusters consisting of 13 atoms were formed with the aid of a pronounced hydrogen spillover effect on readily reducible CeO2 (110) facets. The CoNiCuZnPd HEA sub-nanoclusters exhibited higher activity during the reduction of NO by H2 even at low temperatures compared with the corresponding monometallic catalysts. These clusters also showed a unique structural reversibility in response to repeated exposure to oxidative/reductive conditions, based on the sacrificial oxidation of the non-noble metals. Both experimental and theoretical analyses established that multi-element mixing in quantum-sized regions endowed the HEA clusters with entirely novel catalytic properties.
Spatiotemporal Changes of Forest Cover and Land Surface Temperature Using Geo-Spatial Techniques in Talra Wildlife Sanctuary, Shimla, North-Western Himalaya
Authors: THAKUR PAWAN KUMAR , Samant Sher Singh , Verma Raj Kumar
Published: January 2023

Geophysical parameter such as Land Surface Temperature (LST) plays an important role in studies related to hydrological processes, climate change, Forest Cover Change (FCC) detections, soil moisture estimations, vegetation water stress, etc. Thermal Infrared Sensors (TIRS) for several FCC categories are measured heat signatures. Deforestation, forest fire, grazing, and anthropogenic activities were witnessed in Protected Areas (PAs) forests. For the Single Channel (SC) algorithm and the Split Window (SW) algorithm. The Landsat-5 Thematic Mapper (TM), Landsat-7 Enhanced Thematic Mapper Plus (ETM+), and Landsat-8 Operational Land Imager (OLI) several time-series satellite data have been employed. The overall analysis of FCC showed a significant reduction (-5.59%) in dense forest areas. Despite an overall decrease in pasture and non-forest areas of about 2.99 Km2 between 2000 and 2021, there was a significant increase in these areas between 2000 and 2021 of 7.25% and 0.22%, respectively. The relative comparison of the LST on various FCC categories obtained from SC and SW algorithms revealed a ± 1 Kelvin (K) average difference in the years 2000, 2011, and 2021. The LST retrieved using the SC algorithm shows a strong negative correlation coefficient with Normalized Difference Vegetation Index (NDVI) of R2 = 0.791 in the year 2000 with ⍴ a value of -0.889, 0.750 with ⍴ the value of -0.866 in the year 2011, respectively, whereas the LST obtained using the SW algorithm exhibited a perfect negative Correlation Coefficient (R2 = 0.646 with a ⍴ value of -0.804) with the NDVI for the year 2021.
Phased bidirectional regulation of Notch signaling drives the proliferative regeneration of hair cells in adult mice
Authors: Li Wenyan , Zeng Shan , Jiang Tao , Chen Zheng-Yi , Li Huawei
Published: January 2023

The loss of the vestibular hair cells (HCs) causes balance disorders, and there is little capability to regenerate HCs in adult mammals. Here, we reprogramed adult vestibular sensory cells through bidirectional regulation of Notch signaling in a phase-dependent manner, which recapitulated the dynamic changes in Notch signaling that occur during inner ear development. We observed that the activation of Notch signaling induced the proliferation of supporting cells (SCs) in the damaged adult utricle and primed the proliferating cells with the capacity to regenerate sensory HCs. Further inhibition of Notch signaling could remove the barrier of lateral inhibition and induce the transition from proliferating SCs to HCs. Our results highlight the pivotal roles of Notch signaling in promoting vestibular HC regeneration.
Multidimensional optical tweezers synthetized by rigid-body emulated structured light
Authors: Shen Yijie , Zhu Liuhao , Tai Yuping , Li Hehe , Hu Huajie , Li Xinzhong , Cai Yangjian
Published: January 2023

Structuring light with more extended degrees of freedom (DoFs) and in higher dimensions is increasingly gaining traction and leading to breakthroughs such as super-resolution imaging, larger-capacity communication, especially ultraprecise optical trapping or tweezers. More DoFs when manipulating an object can access more maneuvers and radically increase maneuvering precision, which is of significance in biology and related microscopic detection. However, manipulating particles beyond the three-dimensional (3D) spatial manipulation by using current all-optical tweezers technology remains difficult. To overcome this limitation, we theoretically and experimentally present six-dimensional (6D) structured optical tweezers based on tailoring structured light emulating rigid-body mechanics. Our method facilitates the evaluation of the methodology of rigid-body mechanics to synthesize six independent DoFs in a structured optical trapping system, akin to six-axis rigid-body manipulation, including surge, sway, heave, roll, pitch, and yaw. In contrast to previous 3D optical tweezers, our 6D structured optical tweezers significantly improved the flexibility of the path design of complex trajectories, thereby laying the foundation for next-generation functional optical manipulation, assembly, and micromechanics.
Private Wing Policy Formulation Process, Its Effective Implementation and Associated Factors among Health Workforces in Public Hospitals of Addis Ababa, Ethiopia: Convergent Study Design
Authors: Dessie Esteziyaw , Getinet Tewdros
Published: January 2023

Background: The private wing health policy implementation has unintended policy effects like increasing medication error, absence of medical doctors in working hours, the presence of policy support to unfair revenue share among health workforces and inconsistent revenue-generating for the public ward. However, nothing is known about the policy formulation process and its effective implementation and associated factors. The purpose of this study was to describe the policy formulation process and estimate its effective implementation and associated factors among health workforces in public hospitals of Addis Ababa City Administration, Ethiopia.
Methods: Convergent study design was used from June 18/2020 –Aug 8, 2020 among randomly selected 436 health workforces and purposively selected 6 Health Workforces who were Policymakers in Public Hospitals.
Data were entered onto Epi Data software version 3.1 and exported to SPSS version 20 for further analysis. Data were cleaned by running simple frequency. Simple and multiple binary logistic regression analysis were done to identify associated factors with the outcome variable. Odds ratio along with 95% Confidence interval (CI) were estimated to measure the strength of the association. Then, thematic analysis was done based on codes conceptual relationship using Atlas Ti 8 Software for qualitative part.
Results: Among 436 Health Workforces 409 were participated with a response rate of 93.8%. The overall effective policy implementation was 42.41%. In multiple binary logistic regression analysis, lack of effective coordination among various units (AOR=.293; 95% CI (.170, .505) was significantly associated with effective policy implementation. There were no any other alternative policy options seen during policy formulation by the actors involved. The formulation process was affected by actors involved and the context in which the policy was formulated.
Conclusion: The overall implementation of the private wing policy is not effective and the policy formulation process doesn’t pass-through necessary policy formulation processes. That is why the unnecessary policy effects will remain challenging to the Government. Therefore, the coordination among various units which were designed to implement the private wing health policy should be strengthened, and also policymakers should follow sound policy formulation process.
The potential of ultra short echo time MRI in lung: diagnostic accuracy and image quality evaluation
Authors: Wang Funan , Zhu Liuhong , Lin Chong , Li Xiaoxia , huang Guoqiang
Published: January 2023

Objective
To evaluate the diagnostic accuracy in the detection of pulmonary nodules and image quality of UTE-MRI imaging using ultra short echo time MRI (UTE-MRI).
Methods
A total of 48 patients in our hospital were collected and underwent CT unenhance scan and UTE-MRI scan. The image quality and number of nodules detected by CT were taken as the gold standard. Three diagnostic radiologists independently recorded the image quality (such as visibility and sharpness of normal anatomical structures) of CT and UTE and the number of pulmonary nodules detected. The diagnostic accuracy, subjective image quality and consistency between observations were statistically analyzed.
Results
Among 46 patients, 36 patients (78.2%) had pulmonary nodules on CT image, while 10 patients (21.7%) had no pulmonary nodules. A total of 48 lung nodules were detected, of which 3 were ground glass nodules. On UTE-MRI, a total of 46 lung nodules were detected. Compared with CT, the sensitivity of all MRI readers to detect lung lesions was 95.8%, and the three-observer agreement was nearly perfect (p < 0.001, Kendall Wa (Kender’s Harmonious Coefficientt) = 0.913). The overall image quality score of the observers was high, ranging from good to excellent, and the consistency of UTE-MRI subjective image quality was good: Kendall Wa =0.877, P < 0.001, strong consistency; For tracheal display, the subsegment of bronchus could be displayed, and the wall of the tube was clearly displayed. The Wa value between observers was 0.804,P < 0.001, strong consistency. As for the display of blood vessels, subsegment blood vessels can also be displayed, with clear wall and uniform signal, Kendal Wa =0.823, P < 0.001, strong consistency.
Conclusion
Compared with CT, UTE-MRI can detect pulmonary nodules with a high detection rate, and the image quality is relatively good, and the consistency between observers is strong. The application of UTE-MRI may provide an alternative imaging method for the detection or follow-up of pulmonary nodules and the diagnosis of pneumonia under the condition of reducing ionizing radiation.
The Chloroplast Envelope of Angiosperms Contains a Peptidoglycan Layer
Authors: Tran Xuan , Keskin Erva , Winkler Paul , Braun Marvin , Kolukisaoglu Üner
Published: January 2023

Plastids in plants are assumed to have evolved from cyanobacteria as they have maintained several bacterial features. Recently, peptidoglycans, as bacterial cell wall components, have been shown in the envelopes of moss chloroplasts. Phylogenomic comparisons of bacterial and plant genomes have raised the question of whether such structures are also part of chloroplasts in angiosperms. To address this question, we visualized canonical amino acids of peptidoglycan around chloroplasts of Arabidopsis and Nicotiana via click chemistry and fluorescence microscopy. Additional detection by different peptidoglycan-binding proteins from bacteria and animals supported this observation. Further Arabidopsis experiments with D-cycloserine and AtMurE knock-out lines, both affecting putative peptidoglycan biosynthesis, revealed a central role of this pathway in plastid genesis and division. Taken together, these results indicate that peptidoglycans are integral parts of plastids in the whole plant lineage. Elucidating their biosynthesis and further roles in the function of these organelles is yet to be achieved.