bluuebunny/crossref_metadata_2025 huggingface dataset:
[RETRACTED] Coral CBD Gummies - Let Coral Take Care Of Your Body & Mind! v1
Authors: not provided health
Published: March 2022

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[RETRACTED] Coral CBD Gummies - Cause Concern is Unreliability of Purity & Dosage of CBD In Products! Read More ... v1
Authors: CBD Gummies Coral
Published: March 2022

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Coral CBD Gummies - Cause Concern is Unreliability of Purity & Dosage of CBD In Products! Read More ...
[RETRACTED] Coral CBD Gummies Reviews: Effective Ingredients That Work? Or Bad Complaints v1
Authors: CBD Gummies Coral
Published: March 2022

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Coral CBD Gummies Reviews: Effective Ingredients That Work? Or Bad Complaints
Effect of Anions and Related Organic Compounds on the Kinetics of Thiocyanate Oxidation in a Solar-induced Oxidative System
Authors:   Baikal Institute of Nature Management SB RAS, Batoeva Agnia A.
Published: March 2022

The effect of anions (hydrocarbonates, chlorides, sulfates) and organic compounds (xanthates) on the kinetics of thiocyanate oxidation in a photoinduced iron-persulfate system was studied using natural sunlight as a radiation source. It was found that the introduction of anions into the solution inhibits the degradation of thiocyanates. Hydrocarbonates have the maximum effect, so at a HCO–3 concentration of 1 mM, the processing time required for the complete destruction of thiocyanates increased from 6 to 15.7 minutes. At high concentrations of bicarbonates (≥5 mM), the oxidation efficiency of thiocyanates does not exceed 52 %. The adding of butyl xanthate into the solution has no significant effect on the photochemical oxidation of thiocyanates. In real water matrices (tap water and circulating water of the tailing dump of a gold mining plant), oxidative processes are significantly slowed down. In tap water, this effect is mainly due to the influence of hydrocarbonates, and in waste water, it is due to the multicomponent nature of the water matrix. The efficiency of wastewater treatment from thiocyanates was 100 %, for COD – 82 %, for dissolved organic carbon – 65 %. No cyanides were found after the treatment
Preparation of a New Drug Based on Cis-Dichlorodiamminplatin(II), Arabinogalactan and Aptamer AS‑42 and Study of its Biological Activity
Authors:   Institute of Chemistry and Chemical Technology SB RAS FRC, Starkov Alexander K.
Published: March 2022

A new drug based on a complex of cis-dichlorodiamminplatin(II) with arabinogalactan and aptamer AS‑42 was obtained. The drug is characterized by the methods of XRD, thermogravimetry. IR spectroscopy. Its biological activity has been studied
Utilization of Poplar Leaves (Populus balsamifera L.) by Bioconversion
Authors:   Reshetnev Siberian State University of Science and Technology, Mamaeva O. O.
Published: March 2022

The results on the possibility of utilization of post-extractionation residues of green leaves of balsamic poplar (Populus balsamifera L.) by xylotrophic basidiomycetes Fomitopsis pinicola (strain Fp5–15) are presented. It was found that the most favorable for the growth and development of fungi is the residue after the extraction of alcohol-soluble substances. High growth parameters of fungi are observed on this substrate, such as the growth rate, which is 3.9 mm/day and the growth coefficient is 15.6. During the biocoversion of Fp5–15, F. pinicola utilizes up to 30 % of extractive substances and polysaccharides. At the same time, the utilization of easily hydrolyzable polysaccharides is 24 %, difficult-to-hydrolyze‑30 %. Also, in the process of destruction, up to 12 % of lignin substances are disposed of. The decrease in the mass of the substrate after the bioconversion process is 14 %. It is noted that in the process of bioconversion, the substrate is enriched with protein (up to 24 %)
Microscopic Characteristics and Modelling of Pedestrian Inflow Process with Inactive Persons
Authors: Fan Xinyu , Xia Long , Song Weiguo
Published: March 2022

Inflow and outflow processes are common phenomena in daily life. Many types of research have been conducted to study the features of the outflow process, especially in scenarios with a single room or a straight corridor. A few scholars have paid attention to the movement characteristics of pedestrian inflow. Further explorations are still under great demand. In this contribution, a set of pre-conducted experiments are used to analyze the characteristics of the pedestrian inflow process with inactive persons. In these experiments, inactive persons were required to randomly cease within the room, leading to intensive detour behavior of pedestrians. The characteristics are carefully investigated using gradient analysis and curl analysis. To mimic the aforementioned inflow process, static global field is constructed to heuristically navigate a social force based microscopic model. The proposed model can reproduce the self-organized phenomena in the experiments. Our work can help understand the field feature of the pedestrian inflow process with inactive persons. High chaos level areas can be marked out providing practical information for managers.
The primary B-cell lymphoma of the breast: a clinical case
Authors: Hoffman Alina A. , Fokeev Sergey D. , Bakharev Sergey Yu. , Samoilenkova Olga V.
Published: March 2022

В-cell lymphoma is manifested by a variety of forms, which makes it difficult to establish an accurate lifetime diagnosis and has an unfavorable prognosis. Therefore, every case of primary B-cell lymphoma of the breast, demands attention close attention of doctors of different specialties. The feature of the presented investigation is B-cell lymphoma, that primarily affects the right breast. This type of breast cancer develops as chronic mastitis, confirming the variety of forms of its manifestation, what cause difficulties in making accurate primary diagnosis.
Insurance and Improving Its Strategic Purchase in Iran
Authors: Motie Mahdieh , Dehnavieh Reza , Kalavani Khalil
Published: March 2022

As in most countries, patients, health care providers, and insurance organizations are key components of the health care system in Iran. High rates of growth and development in today's financial markets, have made the insurance industry with its unique calculations and models, a prominent player in this specialized economic sector.
Opposable triphalangeal digital stump transplanted with microvascular anastomoses in patients with frostbitten hands and feet (case report)
Authors:   Privolzhsky Research Medical University, Nizhny Novgorod, Russian Federation, Aleksandrov N.M. , Veshaev I.D. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Russian Federation, Kuptsov D.A. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Russian Federation
Published: March 2022

in frostbite patients. Material and methods Medical histories and long-term results of treatment of two frostbite patients with finger stumps of both hands were reviewed. The triphalangeal finger and the thumb were reconstructed by transplanting the opposable finger stump together with the metacarpophalangeal joint using microvascular and microneural anastomoses. The stumps were mobilized and transplanted to the distal ulnar artery with the venous drainage performed using the dorsal saphenous vein of the hand. Long-term results were examined at 10 years and 2.5 years of surgery. Clinical, radiological, biomechanical and biophysical investigations were produced. Results The bilateral gripping function was restored in recipient stumps without functional damage to the donor stumps. Discriminatory sensitivity of reconstructed fingers was 6mm and 8 mm, the range of active motion in the transplanted joint was 55 and 66 degrees. Discussion Opposable digital stump transplantation with microvascular anastomoses has significant advantages over the classical surgery. The technique allows for one-stage restoration of a finger to have sufficient length, function, adequate blood supply and innervation due to a short digital stump being transplanted with the metacarpophalangeal joint. The advantage over a toe transplant consists of the use of digital structures of the hand that are identical in functionality and the anatomy reducing the need for secondary interventions. Conclusion The method of management can be successfully applied for frostbite patients with hand stumps according to indications.
Modern methods of medication and local therapy for delayed fracture consolidation (literature review)
Authors:   Kazan State Medical University, Kazan, Russian Federation, Sadykov R.I. , Akhtyamov I.F. ,   Kazan State Medical University, Kazan, Russian Federation
Published: March 2022

Introduction Management of post-traumatic disorders of bone regeneration continues to be a substantial clinical challenge in orthopaedic trauma. These include refracture, nonunion, delayed consolidation. The purpose is to explore modern methods of treatment of delayed fracture consolidation. Methods The literature search was produced via open access electronic databases of scientific literature PubMed and eLIBRARY. Search depth was 10 years. Results The article presents methods of medication and local therapy for delayed fracture consolidation. The effectiveness of the use of the ossein-hydroxyapatite complex and vitamin D is reported in patients with normalized healing time of a long bone fracture. The findings showed that bisphophonates, denosumab and strontium ranelate can reduce the risk of fractures with no adverse effect on bone healing. There is controversy on the effect of Teriparatide improving fracture healing. This review will envisage the current clinical trials on bone healing augmentation based on bone grafts, bone substitutes, synthetic growth factors, cell therapy and PRP therapy. Local use of bisphosphonates administered either alone or in combination with other agents is of great interest. Bisphosphonates (etidronate) locally applied in combination with lanthanide ions and calcium for animal fractures demonstrated a positive effect on the reparative process. Conclusion The applicability of medication and local therapy is very high in the treatment of patients with delayed fracture consolidation. Despite numerous studies many questions remain unresolved, and there is a need for the investigations. The local use of bisphosphonates was shown to be promising in the management of delayed fracture consolidation.
Comparative analysis of clinical outcomes of rotator cuff sutures and their dependence on the methods of cuff fixation
Authors:   Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky, Krasnoyarsk, Russian Federation, Denisova A.Yu. , Galov A.A. ,   Krasnoyarsk Regional Clinical Hospital, Krasnoyarsk, Russian Federation, Danilov A.V. ,   Medistar private clinic, Krasnoyarsk, Russian Federation, Narkevich A.N. ,   Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky, Krasnoyarsk, Russian Federation, Serova E.V. ,   Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky, Krasnoyarsk, Russian Federation
Published: March 2022

Partial or full-thickness rotator cuff tear is one of the leading causes of pain and dysfunction in the shoulder joint. Despite the variety of existing surgical techniques, the incidence of re-ruptures after surgical treatment, according to MRI studies, varies from 20 % to 39 %. Purpose To evaluate and compare the clinical results of full-thickness rotator cuff tears surgical treatment using various methods of tendon fixation. Materials and methods A retrospective analysis of case histories, surgery protocols and interviews of patients who underwent surgical treatment for rotator cuff tears at the Krasnoyarsk Regional Clinical Hospital within a period of 6 years was carried out. The sample consisted of 120 patients. All patients were divided into three groups depending on the method of fixation: 1) SutureBridge technique using anchors, 2) classic double-row transosseous suture, 3) double-row transosseous suture using extracortical fixators (Endobutton, Fliptack). Results In the first group, excellent and good results were obtained in 72.86 % and poor results were observed in 18.57 %. In the second group, excellent and good results were obtained in 66.66 % of cases, unsatisfactory results in 18.18 %. In the third group, e xcellent and good results were obtained in 76.47 %, there were no poor outcomes. The best clinical results were obtained in the group of patients who underwent postoperative rehabilitation. Conclusion Anchor SutureBridge technique and classical transosseous suture technique demonstrate comparable long-term outcomes. The absence of poor outcomes in the group of extracortical fixators makes further study of this method promising and should be shown in a larger sample.
The Paradigm Shift in Medical Imaging Education and Training in Europe
Authors:   the University of Algarve, Portugal, Almeida Rui Pedro Pereira de , Silva Carlos Alberto da , Vicente Bianca Isabel da Costa , Abrantes António Fernando Caldeira Lagem , Azevedo Kevin Barros
Published: March 2022

The main goal of this literature review is to discuss the emerging trends, challenges and opportunities in the field of medical imaging education in Europe due to the Covid-19 pandemic scenario that forced the remodeling of the teaching and learning process. A bibliographic search was carried out in the main databases and from resources available in scientific and professional associations in Europe. Exclusion criteria included articles without contributions on distance learning or active learning. Education and training in medical imaging field had to readapt and the usual opportunities for medical imaging and radiotherapy (MIR) students to learn in person in the classroom, lab and clinical settings, had to be quickly transformed into distance learning opportunities. Thus, online education became a pedagogical shift from traditional method to the modern approach of teaching and learning from classroom to Zoom, from personal to virtual and from seminars to webinars, leading to the emergence of innovative teaching models. Moreover, student-centered strategies such as flipped classroom and game-based learning have been recently applied in health professions education with positive and very promising results. In conclusion, due to the pandemic crisis, MIR educators and students find themselves in the situation where they felt compelled to embrace the digital academic experience, allowing the progressive innovation of e-learning. In this context, game-based learning appears to be effective for improving knowledge, skills, attitudes and satisfaction and should be considered as a potential systematic tool in the field of medical imaging education. Therefore, preparedness of radiographers depends on the application of effective training and education methodologies that allows excellent clinical performance and maintaining high quality and safety standards, both through undergraduate course and continuous professional development.
Islamic Fintech, Archaeology of a Discourse
Authors: Belabes Abderrazak
Published: March 2022

The objective of this paper is to present an archaeology of the discourse on Islamic fintech to highlight its mimetic character, i.e. the desire to imitate globalized finance to obtain the same thing in terms of prestige. The archaeology of the discourse revealed the following: (i) The difference between the classic Islamic conception of finance and Islamic fintech lies in the mobilization of digital technology innovation in the field of finance. (ii) The difference between Islamic fintech and conventional fintech lies in the compatibility of Islamic financial products and services with Maqāṣid al-Sharīʿah. After shedding light on the themes of social innovation and slow technology, the study recommends paying special attention to the notion of design thinking in the sense that it offers the opportunity to imagine solutions through the intersection of analysis, intuition, experimentation, and human connection. It is imperative to invest in local startups to innovate solutions that meet both the needs of users and the ambitions of organizations, while taking care not to destroy social structures, and allowing each person to develop its own specific world (milieu, Umwelt, fûdo 風土).
The Role of Institution and Macroeconomic Policy Mix on Economic Growth in Muslim Country
Authors: Wibowo Muhammad Ghafur , Kusuma Hadri , Qizam Ibnu
Published: March 2022

This study examines the role of the fiscal and monetary policy mix on economic growth with the St. model. Louis, which Andersen and Jordan developed in 1968, included the variable quality of institutions (governance) as a moderator. This research model uses the independent variable in the form of money supply (M) as a proxy for monetary policy and government expenditure (G) and government debt (D) as a proxy for fiscal policy. The governance index variable (INS) consists of 6 indicators, namely 1). Voice and Accountability; 2). Political Stability and Absence of Violence/Terrorism; 3). Government Effectiveness; 4). Regulatory Quality; 5). Rule of Law; 6). Control of Corruption. The objects of this research are all member countries of the Organization of the Islamic Conference (OIC), 57 countries. Due to the limited data that can be accessed, 46 countries were selected as research samples with a research period of 2005-2018. The analytical tool used in this study is a moderating panel data regression consisting of 28 equations. This study indicates that fiscal policy (government expenditure) and monetary policy (money supply) have a significant effect on economic growth. The government debt has a negative effect on economic growth in OIC countries. The quality of governance has a positive effect on economic growth in the OIC countries. This shows the important role of the quality of governance in the economy, as in the latest economic growth theory. The quality of governance cannot moderate the effect of the fiscal and monetary policy mix on economic growth in the OIC countries. The governance index plays a more direct role in economic growth, not as an effective moderator for government economic policies. The governance index is more effective in moderating various economic variables, which are private economic activities.
Maqasid-based Consumer Preference Index for Tawarruq Personal Financing (TPF)
Authors: Amin Hanudin , Suhartanto Dwi , Ghazali Mohd Fahmi , Ali Muhammad , Rizal Hamid , Abdul Razak Dzuljastri
Published: March 2022

Relatively, maqasid al-Shariah is a missing dimension element in the available tawarruq personal financing, resulting in a convergence of this facility and its traditional counterpart. This work examines the consumer preference of tawarruq personal financing using the maqasid-based consumer preference index (MCPi). Drawing upon the MCPi, the present study examines consumer preference on the offered Tawarruq personal financing by 7 Islamic banks in Malaysia based on valid 456 usable questionnaires. The primary findings obtained indicate that all banks somewhat have a moderate MCPi. These include Bank Islam Malaysia Berhad (BIMB), Bank Muamalat Malaysia Berhad (BMMB), Maybank Islamic, CIMB Islamic, RHB Islamic, Kuwait Finance House and Al-Rajhi Bank. This study examines a new approach to measure consumer preference using the MCPi. Our contributions are confined to these particular variables – Educating Customer, Establishing Justice and Promoting Welfare. Our study also limits its perspective on the general context of tawarruq personal financing. Future works may provide different perspectives on these interrogations. This study provides a new index for Islamic banks to manage tawarruq personal financing products according to maqasid al-Shariah effectively. This study introduces a new measure of consumer preference of tawarruq personal financing namely the MCPi in the context of Malaysia.
Correlation of radiological parameters with cytological finding in the diagnosis of thyroid swelling
Authors: Kumar Manish , Kumar Amar , Giri Swati Sucharita , Rabha Dharitri , Richa
Published: March 2022

Thyroid gland diseases are the most common endocrine disease seen in clinical practice after Diabetes mellitus. Ultrasound parameters along with correlation with cytology finding helps in differentiate between benign and malignant thyroid nodule.

The purpose of this study was to study the sonographic features of various benign and malignant thyroid nodules, and to correlate the sonographic findings with Fine Needle Aspiration Cytology (FNAC) and so as to evaluate the accuracy of ultrasonography in diagnosing benign and malignant nodules.

The study was conducted in the Pathology department in collaboration with the Radiology Department on 209 patients who were send for ultrasound for thyroid swelling. These patients were further send for fine needle aspiration to the pathology department.

The majority of cases which turned malignant on cytology report in this study have association with ultrasound features like predominant solid lesion, hyperechoic lesion, irregular margin, AT ratio greater than 1, absent peripheral halo, microcalcification along with increased internal vascularity and solitary nodules.

Ultrasonography of thyroid nodules along with fine needle aspiration cytology serves as a best screening test to detect malignancy in outpatient department. The use of different parameters in ultrasound helps in categorizing the lesion and their management. In this study we have association with ultrasound features like predominant solid lesion, hyperechoic lesion and irregular margin, AT ratio less than 1, absent peripheral halo, microcalcification along with increased internal vascularity and solitary nodules with malignancy on cytology.
Cytohistological and immunohistochemical correlation of cutaneous neoplastic lesions: Three year retrospective study
Authors: Raman Sarojini , Gupta Ritika , Sharma Nikhil
Published: March 2022

: Neoplastic lesions in cutaneous and subcutaneous region comprise a large group of benign and malignant entities of different lineage. Clinical, morphological features and prognosis of these lesions differ a lot. For diagnosis FNAC (Fine needle aspiration cytology) is the first technicque applied followed by histology, immunohistochemisty (IHC) and so on.

: Cytological evaluation of cutaneous and subcutaneous neoplasms and correlate with histopathology and IHC.

Study of all palpable cutaneous and subcutaneous swellings presenting to cytology OPD (Out patient department) with further histopathological correlation in the three-year duration.

: FNA cytosmears of the cases stained with leishman stain in most of cases. Histopathological and IHC correlation done in available cases.

: The data are expressed in descriptive statistics measures such as percentages and proportions.

Out of 1032 total cases, most of the cases were benign (94.3%) with fewer malignant cases (5.7%). Lipomas 562(56.31 %) were the largest group among benign lesions followed by benign spindle cell lesions 286(28.65%). Metastatic (22, 64.7%) lesions were more in number than primary cutaneous malignancies (12,35.2%). Among adenocarcinomas, 4 metastatic cases (0.38%) from lung and breast each and among squamous cell carcinomas (SCC), 7(0.67%) primary SCC were seen. Biopsy correlation was available in 134(12.98%) cases and IHC done in 14(1.35%) cases.

: Cutaneous neoplasms though benign in most of the cases, can be of critical aetiology with dismal prognosis. Hence they should not be taken lightly and diagnosed specifically with the help of imaging and cyohistological study whenever needed.
Rare case study of Covid agitation: The novel sinner causes a diagnostic dilemma
Authors: Bhadauria Gyanendra Singh , Singh Swarnima , Patra M K
Published: March 2022

COVID-19 pandemic has taught us a whole new set of medical terminologies. Since its inception, COVID-19 has claimed millions of lives and continues to haunt mankind. CNS manifestations of COVID-19 haven’t been explored thoroughly and leave a grey area in current knowledge. Since most of the cases with CNS manifestations have been ignored and reached higher centers very late, the mortality rate has been high and further study has been limited in this subset.

Here 02 cases of COVID-associated CNS infection presenting with atypical neurological symptoms have been reported who could have been easily misdiagnosed and treated inadequately causing abysmal results.

MRI brain combined with SARS-CoV-2 RNA testing are the mainstay diagnostic modalities clubbed with strong clinical suspicion.

COVID-19 was considered as a respiratory disease but the latest literature clearly highlights its multisystem involvement. CNS involvement in COVID-19 has been well-established now and needs to be treated aggressively and appropriately.
A case report: role of curative toilet mastectomy with latissimus dorsi flap recostruction in locally advanced breast cancer
Authors: Tippani Avinash , Bachu Brahmani
Published: March 2022

Breast Cancer is a systemic disease with rising incidence all over World. In India where most of the patients present with advanced stage. Multimodal treatment with evolving research in breast cancer showed an evidence of increase in survival in Locally Advanced Breast Cancer (LABC). Based on this selected patients with LABC which are inoperable may have a survival benefit with Local Surgery and Adjuvant treatment. We present a case from Semi-Urban locality in India where facilities are poor.

A Case Report of curative Mastectomy in Fungating Breast Cancer which progressed on Chemotherapy from a tier- 2 city with limited resources showed increased survival which can be taken as pilot study for advanced trials and research.
Optimal Placement of Electric Vehicle Charging Station in Distribution System Using Meta-Heuristic Techniques
Authors: Golla Naresh Kumar , Sudabattula Suresh Kumar , Suresh Velamuri
Published: March 2022

Technological findings recommend that Electric Vehicles (EVs) play a vital role in the road transportation system. EV's are becoming more prominent as formal vehicles have a substantial effect on the atmosphere. The rising adoption of EVs will lead to an increase in the number of charging stations that would profoundly impact the power grid. The inappropriate forecasting of EV Charging Stations (EVCSs) has a detrimental effect on the distribution system. Therefore, the selection of the optimum placement of EVCS in the power grid is a significant problem. In the proposed approach, an IEEE 33 Bus system is considered for optimal placement of EV charging station, with the account of optimal loads of the buses. The analysis was carried for an IEEE 33 BUS system using the Loss Sensitivity Factor (LSF) and power flow by Newton Raphson method. LSF was determined for various buses considering the system voltage, load (real and reactive power), and losses in the system. Also, the results are compared with the conventional method, Particle Swarm Optimization (PSO) and Harris Hawks Optimization (HHO) algorithms. Finally, the reliability test was carried out for optimal placement of EVCS in an IEEE 33 BUS system.
Mathematical Model of the Rapeseed Drying Process with the Use of Electromagnetic Microwave Radiation Based on Heat Calculations
Authors: Ganeev Ildar , Karimov Khasan , Permyakov Valeri , Mudarisov Salavat , Khasanov Eduard
Published: March 2022

Few studies have been devoted to mathematical modelling of the drying process of various crops using microwave drying units. The paper presents a mathematical model of the rapeseed drying process using electromagnetic microwave radiation based on heat calculations. The research aims at mathematical modelling of thermal processes of rapeseed heating when treated by electromagnetic microwave radiation. The computational and technological scheme of drying has been developed. According to the scheme, the drying process includes several cycles, which, in turn, consist of two stages. In the first stage, rapeseeds are heated to the desired temperature by applying electromagnetic microwave radiation. At this stage, there is an intensive release of moisture from rapeseeds, accumulating in the interseminal space. In the second stage, rapeseeds are blown off with atmospheric air to create a fluidized bed. The developed mathematical model allows predicting such parameters as the power of the microwave generator and fan depending on the drying unit capacity.
Modelling the Effects of Hydraulic Force on Strain in Hydraulic Structures Using ANN (Haditha Dam in Iraq as a Case Study)
Authors: Almawla Atheer Saleem , Lateef Assim Mohammed , Kamel Ammar Hatem
Published: March 2022

The strain on any structure is a critical issue worldwide, resulting from loads on the structure. An exact prediction at all the expected strains ranges on the dam will pave the way for better dam management under different discharges. The main aims of the present paper are to study the behaviour of strains on the dam and create a model based on ANN techniques that can be used to predict the strain on the model of the Haditha dam. The ANN is a computational model that simulates the method neurons work in the human brain. The research includes a study of the strains on the dam body and the gate. The input of the present model includes gate opening, discharge, depth of upstream water, and force on the dam body and gate. The model has been applied by using 150 actual testes of strain in the hydraulic laboratory. The model has been achieved by using a MATLAB software with hyperbolic sigmoid transfer function and three nodes. The accuracy of the model was achieved by using some statistical indicators. The results show the ANN is capable of predicting the strain on the Haditha dam with high accuracy. The regression for both strains on the dam body and the gate was more than 89% for all training, validation, testing, and all samples.
Evaluation Outcomes Associated with Alternative Dosing Strategies for Piperacillin/Tazobactam: A Systematic Review and Meta-Analysis
Authors: Yang Hui , Cui Xiangli , Ma Zhuo , Liu Lihong
Published: March 2022

A better dosing strategy can improve clinical outcomes for patients. We systematically reviewed the literatures to determine whether any clinical benefits exist for piperacillin/tazobactam by extended or continuous infusion. Methods - A search of PubMed, Web of Science, ProQuest, ScienceDirect, Cochrane, Embase and related ICAAC and ACCP conferences were conducted up to September 5, 2015. Randomized controlled and observational studies that compared extended or continuous infusion with conventional intermittent infusion of piperacillin/tazobactam were identified from the databases above and analyzed. Two reviewers independently evaluated the methodology and extracted data from primary studies. A meta-analysis was performed using Revman 5.2 software. The quality of each study was assessed. Sensitivity analysis and publication bias were evaluated. Results - Three randomized controlled trials and twelve observational studies were included in this study. All included studies had high quality and no publication bias was found. Compared to the conventional intermittent infusion approach, the extended or continuous infusion group had a significant cost effectiveness (OR -0.89.02, CI (-114.69,-63.35), P<0.00001). No statistical difference was observed for clinical cure rate (OR 1.64, 95% CI (0.88, 3.30), P=0.12) between the two dosing regimens. The sensitivity analysis showed the results were stable. Conclusions - Our systematic review and meta-analysis found that the outcomes associated with alternative dosing strategies of piperacillin/tazobactam have changed compared with conclusions before for several literatures with large samples published. Further data on the outcomes should be generated for a better understanding of the extended or continuous infusion strategy. On the whole, our meta-analysis suggested that the extended or continuous infusion should be recommended for clinical use only considering its economic advantage, but there was no significantly higher clinical cure rate and lower mortality rate compared with the conventional intermittent infusion. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
Organogels in Drug Delivery: A Special Emphasis on Pluronic Lecithin Organogels
Authors: Alsaab Hashem , Bonam Sindhu Prabha , Bahl Dherya , Chowdhury Pallabita , Alexander Kenneth , Boddu Sai HS.
Published: March 2022

Organogels have emerged as an alternative carrier for small and macromolecules via transdermal, oral, rectal and ophthalmic routes. Pluronic lecithin organogels (PLO gels) are lecithin-based organogels widely used in compounding pharmacies as a vehicle for enhancing the transdermal permeability of many therapeutic drugs. However, the scientific and systematic evidence in support of how well PLO gels help in transdermal delivery is scanty. Recently, some clinical studies have reported nearly complete lack of bioavailability of certain topically administered drugs from PLO gels. The present review aims at summarizing gels and organogels, with a focus on the use of PLO gels in transdermal drug delivery. A special emphasis is placed on controversies looming over the use of PLO gels as a delivery platform for drugs via transdermal route. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
Creencias sobre la diversidad sexual en padres con hijo/a homosexual
Authors: Ospina Botero Mireya , Hernández Enríquez Valentina
Published: March 2022

Este artículo es producto de la investigación sobre “Diversidades sexuales y familias”, realizada por la línea de investigación en pedagogía, formación y desarrollo humano de la Universidad Católica de Pereira – UCP. Se pretende mostrar los estereotipos frente a la diversidad sexual que tienen los padres con hijos/as homosexuales. La metodología desde la cual se desarrolla la investigación es cualitativa, de corte biográfico – narrativo, para ello se realizaron 20 entrevistas a profundidad y un grupo focal con madres de hijos/as homosexuales. En los principales resultados se identificaron tres grandes categorías emergentes, vinculadas a los estereotipos: influencia religión, miedos y construcciones culturares respecto a la identidad de género.
Histeria: preguntas y sufrimiento
Authors: Ezequiel Ferreyra Leandro , Ismael Zucaría Julio
Published: March 2022

El presente escrito presenta una lectura de la histeria desde la perspectiva del valor fálico, desde donde se propone que la característica principal de este tipo clínico será la identificación al falo. Por este motivo, se toma la disyunción entre demanda y deseo en el sujeto histérico, sin dejar de lado el goce y el sufrimiento. También, se trabaja la articulación de estos elementos conceptuales con la orientación clínica basada en la pregunta, en el caso de la histeria: ¿Qué es una mujer? Estas nociones serán acopladas en una viñeta clínica, entregando como resultado la alianza clínico-conceptual necesaria para la transmisión del psicoanálisis de orientación lacaniana.
Evaluación de desempeño por competencias en una empresa familiar de transporte
Authors: Matabanchoy Tulcan Sonia Maritza , Dorado Martínez Álvaro Darío , Guevara Canchala Nayive Tatiana , Narváez Calpa Yudy Alejandra
Published: March 2022

Las empresas familiares se convirtieron en una base económica fundamental, por lo que se denota importante fortalecer los procesos de Gestión de Talento Humano, con el fin de aportar en el desarrollo humano y organizacional. Dentro de estos procesos, se encuentra la evaluación de desempeño como herramienta estratégica que identifica aspectos de mejora y alternativas de solución dentro de las empresas. Por ello, la investigación tiene como objetivo diseñar la evaluación de desempeño por competencias en una empresa familiar de transporte, a partir del enfoque cualitativo de tipo fenomenológico, con la participación de 5 líderes de la empresa en mención. Como resultado se encontró que la evaluación de desempeño responde a una lógica de proceso bajo la consigna de retroalimentación continua. Se concluye que la relevancia de la evaluación se adecua a las dinámicas de la empresa siendo acorde a su plataforma estratégica.
Audyt społeczny jako propozycja wzbogacenia repertuaru metod badań społecznych
Authors: Desperak Iza
Published: March 2022

Artykuł przedstawia metodę audytu społecznego – narzędzia badawczego wypracowanego w celu mierzenia dyskryminacji w sferze zatrudnienia. Audyt społeczny używany jest do badania dyskryminacji na poziomie rekrutacji oraz badania warunków pracy pracowników, a zwłaszcza pracownic w przedsiębiorstwach, które ubiegają się lub uzyskały certyfikaty CSR – Corporate Social Responsiblity. Metodologia audytu łączy podejście ekspery­mentalne ze strategią badań terenowych: obserwacji jawnych i niejawnych, różnego rodzaju wywiadów, kontroli dokumentów skoordynowanej z audy­tem księgowym i kontrolą warunków BHP. W podejściu tym można zauważyć analogię do metodologii teorii ugruntowanej lub strategii badań ewalu­acyjnych. W tekście analizuję przeprowadzone w Polsce audyty – zarówno prowadzone na zlecenie organizacji pozarządowych, jak i te zorganizowane w celu przetestowania tej swoistej metody – wskazując na jej wady i zalety.
komputerowe wspomaganie badań jakościowych. zastosowanie pakietu NVivo w analizie materiałów nieustrukturyzowanych
Authors: Brosz Maciej
Published: March 2022

Artykuł poświęcony jest wykorzystaniu oprogramowania NVivo w analizie danych jakościowych. Główny wątek opracowania odnosi się do problemu redukcji danych jako procesu towarzyszącego analizie jakościowej. Wykorzystanie oprogramowania nie musi oznaczać niekontrolowanego procesu zmiany postaci danych i tym samym utraty istotnych wymiarów doświadczeń zgromadzonych w materiale badawczym. Najnowsze narzędzia z rodziny CAQDAS (np. NVivo 8, 9) pozwalają zminimalizować ów problem poprzez umożliwienie pracy na materiałach źródłowych w formie niezmodyfikowanej. Artykuł przedstawia przykłady analizy danych w postaci tekstów, obrazów, nagrań audiowizualnych. Dodatkowo przedstawione zostały wybrane narzędzia wspomagające proces kodowania.
Analiza danych jakościowych przy użyciu programu NViv o a zastosowanie procedur metodologii teorii ugruntowanej
Authors: Niedbalski Jakub , Ślęzak Izabela
Published: March 2022

Celem artykułu jest wskazanie możliwości oraz ograniczeń programów typu CAQDAS (Computer-Assisted Qualitative Data Analysis Software) w zakresie realizacji badań jakościowych. Nasze rozważania opieramy na osobistych doświadczeniach zdobytych podczas realizacji badań prowadzonych zgodnie z zasadami metodologii teorii ugruntowanej (MTU) i z wykorzystaniem programu NVivo w wersji 8. W artykule rozważamy problem wpływu nowoczesnego oprogramowania CAQDAS reprezentowanego przez program NVivo 8 na sposób organizowania i realizacji badań jakościowych, prowadzonych zgodnie z procedurami TU. Prezentujemy także najważniejsze – naszym zdaniem – funkcje dostępne w programie NVivo 8 i wskazujemy ich aplikacyjny charakter w badaniach opartych na metodologii teorii ugruntowanej.
An old species and a new frontier: Some thoughts on the taxonomy of Homo erectus
Authors: Wang Qian , Tobias Phillip V.
Published: March 2022

The taxonomic impact on Homo erectus induced by a .preerectus- out-of-Africa. paradigm is preliminarily discussed in this article. Some of the early Homo species in Asia should be allocated to another taxon rather than to H. erectus, although their real identities are not yet readily apparent. Asian H. erectus may be taxonomically distinct from African H. ergaster. Differences between two samples of H. erectus from Java and China, suggesting taxonomic diversity or only geographical variances between these subsets, need further study. Reasons are advanced against the proposal to lump H. erectus into H. sapiens.
Molecular anthropology: Touching the past through ancient DNA retrieval. Methodological aspects
Authors: Witas Henryk W.
Published: March 2022

The revolution which introduced new techniques of molecular biology applied to DNA analysis enormously accelerated the progress in most areas of medicine and biology. Techniques such as polymerase chain reaction (PCR), restriction analysis and sequencing are widely used for diagnosis of a number of diseases, for genetic screening, phylogenetic analysis and population studies. Moreover, it became possible to study genetic relationships of extinct to contemporary organisms and even to follow evolutionary events. Variation in DNA sequences, especially that of humans, is fascinating not only for our own sake, but also because of the inferences that can be drawn from it about our recent evolution, demography and movements. Selected problems arising during ancient DNA (aDNA) isolation and analysis are discussed. Environment and time related factors altering the structure of nucleic acids as well as contamination of isolated material are among methodological problems that arise during the procedure of isolation and processing of aDNA. Resolving them is of great importance for the authentication of the identified sequences. Most common informative targets of aDNA are presented and among them mtDNA, and the sequences localized within nuclear DNA. The first, as well as the most important findings in the field are mentioned.
Social-class differences in Poland pronounced in stature, but absent in gene frequencies
Authors: Gronkiewicz Lidia
Published: March 2022

The marked social-class differences in physical growth of youth, as well as in a variety of health-related biological characteristics of adults, observed in many industrial societies are as a rule interpreted as nongenetic in nature and therefore as purely phenotypic manifestations of social inequalities in living standards. However, this tacitly adopted .no genetics. assumption has very seldom been subject to any empirical validation. The present study is an attempt to provide such validation for the population of Poland.

The material was collected over the period from 1960 to 1990 and drawn from cases of disputed paternity. It comprises a total of 8861 adults of both sexes; roughly half of them are males, the presumptive fathers. It was found that throughout the period of several decades covered by this study no significant differences appeared between the various social strata in allele frequencies of any of the following 8 genetic loci: ABO, MN, Rh(D), Hp, Gm(a), AcP, PGM1, EsD. Nor is there any suggestion of long-term trends in allele frequencies for any of the above loci. This pattern is in sharp contrast to the strikingly regular social gradients, and intense secular trends, observed in the population of post-war Poland in stature and age at menarche. It is postulated that the above findings are consonant with the .no genetic component. hypothesis.
Marital status and biological condition of Polish males
Authors: Lipowicz Anna
Published: March 2022

Strong evidence for marital differences in mortality has been demonstrated in a large number of countries. Married men and women have lower death rates than unmarried individuals within each adult age group. Additionally, married persons tend to be healthier as compared to unmarried. In the literature two explanations for this patterning have been proposed. .The health selection hypothesis. suggested that disabled or less healthy people are not as likely to get married as the healthy ones. In .the social causation hypothesis ., marriage yields health benefits through emotional and social support which may act as a buffer against the effects of life stress. In this study, .the social causation hypothesis. is supported.
​Effect of Germination on the Physical and Functional Properties of Brown Rice Flours
Authors: Mohmmed Naseerunnisa , Kuna Aparna , Sarkar Supta , Azam M.M. , Prasanna K. Lakshmi
Published: March 2022

Background: Germinated brown rice (GBR) flour recently gained popularity due to its nutritional and health-promoting benefits and is being used as a functional ingredient in formulation of various food products, replacing rice flour. GBR is prepared by soaking brown rice (BR), more specifically, the embryo of brown rice in water to promote grain activation under controlled conditions. Methods: Present study was aimed to develop the GBR flours of MTU 1010 and KNM 118 at various germination hours (0, 12, 24, 36, 48 and 72 hours) and to study the effect of germination on the physical and functional properties of BR and GBR flours. Result: Our findings revealed that germination showed significant variations in l*, a*, b* and DE* of BR flours of both varieties. Germination significantly decreased the bulk density, tapped density, oil absorption capacity, water activity. Germination also considerably improved the water absorption capacity at 24 hours of germination and foaming capacity of MTU 1010 and KNM 118 GBR flours. BR flour had the least gelation concentration (LGC) of 8% and 6% which increased to 12% and 10% after 24 h germination in MTU 1010 and KNM 118 GBR flours, respectively.