bluuebunny/crossref_metadata_2025 huggingface dataset:
The right-brain alternative
Authors: Zheleznyak Olga
Published: January 2023

The era of left-brain dominance is beginning to give way to a new world in which right-brain ideals prevail and creativity is valued. Being a kind of opposition to the information age, they become a response to the challenges of the right-brain thinking age and drivers of development, presenting right-brain skills as most relevant to life and business. Creative industries/economies/professions are increasingly in demand as an alternative to the “classical” industry, as creativity provides a competitive advantage by adding value to a service or product.
Seams of borders and networks of cities: Russia in the late 18th century
Authors: Gryaznova Nadezhda
Published: January 2023

Using an extensive archival, memorial and historical material, the article describes the processes that took place in the late 18th century in the organization of the Russian Empire through the example of the changes in the territorial organization of the Tambov Province. The author analyzes the principles underlying these changes, as well as the boundaries of settlement territories and, in particular, cities. Russian and Western European cities are compared and different reasons for their emergence and the political motives of their changes are emphasized.
Indicator “Risk of harm from alcohol use” (ASSIST score ) in patients with schizophrenia and related disorders
Authors: Hmara N. V. , Skugarevsky O. A.
Published: January 2023

Objective. To establish the relationship between the ASSIST score (Humeniuk R. et al. 2008) «risk of harm from alcohol use» (RHAU), impaired social functioning and manifestation of aggression in patients with schizophrenia and related disorders.

Materials and methods. From 2014 to 2020 a comparative, one-stage, observational study was conducted on the basis of the Gomel Regional Clinical Psychiatric Hospital with a sampling formation using directional selection method. Patients who met diagnostic criteria of schizophrenia (F20) or acute psychotic disorder (F23) according to ICD-10 were included in the study. The following assessment methods were used: 1) screening for alcohol use – ASSIST scale (Humeniuk R. et al. 2008), 2) determination of the level of aggression OASCL (Yudofsky S. C. 1986).

Results. The entire sample of 123 people examined by us was divided into 3 groups depending on the level of RHAU. The first group «ASSIST 0» (n=37) was accepted as a control group, since RHAU was equal to 0. The second group is «ASSIST up to 10» (n=42), with minimal RVUA (1-10 points on the ASSIST scale). The third group «ASSIST over 11» (n=44) combines moderate and high RHAU. The group study did not show any differences between men and women in alcohol consumption and aggression within the groups. Comparison of 3 groups, and their subsequent pairwise comparison, made it possible to establish statistically significant differences in social dysfunction groups (decrease in the working status of «ASSIST 0» – 81%, «ASSIST over 11» – 73%, «ASSIST up to 10» – 45%) and of aggression (OASCL total score H 62.4=p≤0.001: physical aggression vs. others H=45.2 p≤0.001).

Conclusion. In patients with schizophrenia and disorders close to it, the «risk of harm from alcohol use» indicator (ASSIST scale) indirectly indicates the formation of psychosocial dysfunction and indicates a differentiated effect of alcohol in the display of aggression in this group of patients.
Effect of budesonide and azithromycin on the chemotaxis of blood monocytes and lymphocytes in patients with chronic obstructive pulmonary disease
Authors: Kadushkin A. G. , Tahanovich A. D. , Kolesnikova T. S. , Khadasouskaya A. V.
Published: January 2023

Objective. To evaluate the ability of a combination of budesonide and azithromycin to influence the migration of blood monocytes and lymphocytes in patients with chronic obstructive pulmonary disease (COPD).

Materials and methods. Peripheral blood mononuclear cells from patients with COPD (n=8) were incubated with glucocorticoid budesonide (10 nM), macrolide antibiotic azithromycin (10 µg/mL), or their combination, and then transferred to chemotaxis chambers containing chemokines RANTES (CCL5, 10 nM) or IP-10 (CXCL10, 10 nM). Cells migrated to the lower compartment of the chamber were collected, stained with monoclonal antibodies to CD3, CD14, CD19, CD45 and counted on a flow cytometer.

Results. Azithromycin alone and in combination with budesonide inhibited the migration of blood T-lymphocytes and B-cells and enhanced the migration of blood monocytes to RANTES and IP-10. The combination of azithromycin and budesonide had a more suppressive effect on the chemotaxis of blood T- and B-lymphocytes to RANTES and IP-10 than budesonide alone. The combination of azithromycin and budesonide had an effect similar to azithromycin alone on the migration of blood T- and B-lymphocytes, as well as monocytes in patients with COPD.

Conclusion. The results of the study demonstrate the ability of azithromycin alone to modulate the chemotaxis of peripheral blood monocytes and lymphocytes in patients with COPD and the lack of advantages of its combination with budesonide.
Policy Issues Affecting the Health of Older Individuals in the United States
Authors: Ozobokeme Oyintoun-emi , Okobi Okelue Edwards , Udo II Uduak A. , Boms Maureen G. , Adeosun Adeyemi , Koko Jovita , Agu Chukwuebuka , Izundu Ijeoma Christia , Egberuare Emmanuel O. , Ogunlami Oluwarotimi A.
Published: January 2023

The aging population is growing, in the United States and the rest of the world. Developed nations are now facing challenges with providing for this increasing unit of population. Aged adults account for a significant part of individuals utilizing health care services in these countries. As a result of this growth, long-term policies in the healthcare of the elderly need to be reviewed. This manuscript offers insight into the policies and the several elements that affect the provision of healthcare to the aging populace. Some of the issues addressed include medical care needs versus supply, alternatives to institutionalization, alternative delivery systems, financing long-term care services, the role of informal support systems, housing, and income maintenance. The demand for use of long-term care services is also significantly growing. Socioeconomic status and health behaviors throughout life affect the need for these services. However, financing and access to these services have become a concern for governments, and papers like this offer relevant data which can be used to reform and make informed policies.
Exercise Intensity and Its Relation to Sperm Count on Healthy Male Adults
Authors: Davin Samuel , Halim Wardina , Wiyasihati Sundari Indah
Published: January 2023

Physical activity is well known for maintaining fitness and health. Recent studies also found that low semen quality and quantity are associated with the risk of many diseases and life expectancy. We conducted a literature search with key concepts of “exercise”, “sperm count”, and “adult”. The search was carried out through comprehensive literature searches on 4 databases (Pubmed, Web of Science, Scopus, and Google scholar), reference searches or citation matching, and/or other method searches. The literature search was done in November 2022. We identified 17 literatures that analyzed these correlations. Among them, 7 articles showed that there is a correlation between exercise intensity and sperm count. However, there are other studies that showed no significant correlation between the intensity of exercise and sperm count. In conclusion, physical activity in sedentary adult males has shown a positive effect on sperm count. However, athletes showed no significant decrease in sperm count.
Dietary Intake and Physical Activity in Relation to Obesity in 6-12 Years Old Children at SDN Banyu Urip III/364 Surabaya
Authors: Putri Valensia Arita , Aprilawati Dwi , Irmawati Mira , Widjaja Nur Aisiyah
Published: January 2023

Introduction: Obesity is a multifactorial disorder characterized by excessive accumulation of fat in the body. Obesity can increase the risk of various diseases in adulthood. The aim of this study is to find the relationship between carbohydrates, protein, fat, fiber intake and physical activity to obesity rate in school-age children. Methods: This was an analytic observational study and a cross-sectional design. This study was held at State Elementary School (SDN) Banyu Urip III/364 Surabaya from February to October 2022. The sample of this study was chosen by random sampling of all students at SDN Banyu Urip III/364 Surabaya. The data collected were nutritional status with anthropometric measurements, food intake with the 24-hour Dietary Recall (24HR), and physical activity with the Physical Activity Questionnaire for Older Children (PAQ-C). The data were analyzed by Chi-Square test and logistic regression analysis. Results: The prevalence of obesity in this school is 19.57%. The obese students have a high carbohydrate intake (100%), high protein intake (83,33%), high fat intake (94,44%), and half of them have a high fiber intake (50%). Majority of obese students do low-intensity physical activity. From the analysis, there is a relationship between carbohydrate intake (p=0.045), fat intake (p=0.013), fiber intake (p=0.010), and physical activity (p=0.000) with obesity. However, there is no relationship between protein intake (p=0.264) and obesity.
Endoscopic diagnosis of a colonic localisation of a mantle cell lymphoma
Authors: Lambrechts C , Van der Wijst E , Bries G , Bogaert J , De Schepper H , Van Hauthem P , Schoeters P , De Maeyer M
Published: January 2023

Extra-nodal localisations of mantle cell lymphomas are most frequently found in the gastrointestinal tract. It is therefore important for an endoscopist to be familiar with the endoscopic image of a mantle cell lymphoma. In this case series of three patients with colonic involvement of mantle cell lymphoma, we discuss the endoscopic diagnosis.
Cold snare endoscopic submucosal resection
Authors: Van Overbeke L , Mertens G
Published: January 2023

A 76-year-old lady was referred for resection of a large (50 mm) sigmoidal sessile adenoma (Paris classification IIb, JNET2a, Figure A). After submucosal injection with diluted indigo carmine and adrenaline, the lesion was resected using cold snare piece-meal technique (Captivator 10 mm cold single use snare, Boston). Because of a zone with presumably residual polyp tissue, an additional resection of submucosa was performed (Figure B, arrow). This resection turned out to cut deeper than expected and reached as far as the circular muscles (Figure B, arrowhead). No preventive clips were placed. No complications occurred, there were no immediate or late bleedings.
Pre-Endoscopy real-time PCR testing for SARS-CoV2 does not reduce health care workers infection and is associated with a higher reduction of endoscopic activity in an outpatient setting
Authors: de Pretis N , Sferrazza S , Michielan A , Merola E , Bevilacqua N , De Marchi F , Marzi L , Teani I , Comberlato M , de Pretis G
Published: January 2023

Objective: The role of pre-procedure SARS-CoV2 testing in digestive endoscopy is still debated. AGA guidelines recommend against pre-procedure testing considering low prevalence of SARS- CoV2 infection in the general population and low incidence of infection among endoscopy units Health Care Workers (HCWs). However, no studies have compared pre-procedure testing associated to symptom screening vs. symptom screening alone in reducing the risk of infection for HCWs. Main aim of the present study is to compare the risk of infection for HCWs in different Endoscopy Units adopting different pre-endoscopy screening and operating in two nearby hospital of the same region in Northern Italy in pre-vaccination period. For outpatients in the Endoscopy Unit of Trento (Unit 1) only pre-procedure symptom screening was performed, while in the Endoscopy Unit of Bolzano (Unit 2) pre-procedure symptom screening and negative pre-procedure real-time PCR were requested. Secondary aims were to assess the impact of pre-procedure real-time PCR testing on endoscopic activity and diagnostic delay.

Design: Retrospective data collection on a prospectively maintained database was performed, including outpatient endoscopy procedures performed between June 1st 2020 and February 28th 2021 in Unit 1 and Unit 2.

Results: No differences in terms of infection rate in HCWs have been identified in Unit 1 and Unit 2 (9.0 vs. 19.3% P=0.2) over a nine-month period. Moreover, in the unit performing pre- procedure real-time PCR before endoscopy a significantly higher reduction in endoscopic activity has been recorded (61.9% vs. 53.4%; P<0.01). In patients with positive real-time PCR, endoscopy was performed with a mean delay of 61.7 days (range 9-294) and 22.5% of them were lost at follow-up and did not undergo any endoscopic procedure in the following 12 months.

Conclusions: This study supports the AGA recommendation suggesting that pre-endoscopy real-time PCR is an expensive and time-consuming procedure without proven benefits in an outpatient setting.
Changes in bone turnover markers in adolescents with gastroesophageal reflux disease treated with lansoprazole
Authors: Islek A , Erol Kizilelma N , Keskin H , Ozturk N
Published: January 2023

Background: Proton pump inhibitors (PPIs) have been suggested to lead to bone resorption, while the effects of PPIs on the bone mineral metabolism in children has received only limited attention in literature to date. The present study investigates whether lansoprazole alters bone turnover markers in adolescents with gastroesophageal reflux disease (GERD). Patients and methods: Included in the study were adolescents aged 16–18 with GERD and a healthy volunteers group. The GERD patient group was treated with lansoprazole 30 mg once daily for eight weeks. The serum calcium, phosphorus, magnesium, alkaline phosphatase (ALP), parathormone (PTH), 25 (OH) vitamin D, osteocalcin and urinary calcium, creatinine, deoxypyridinoline (DPD), collagen type-1 crosslinked C-telopeptide (CTX) and collagen type-1 crosslinked N-telopeptide (NTX) of both groups were studied before and after the end of the treatment. Results: A comparison of the 30 patients with GERD and the 30 volunteers revealed no significant difference in the serum calcium, phosphorus, magnesium, ALP, urinary calcium/creatinine ratio, 25 (OH) vitamin D and PTH levels measured before and after the lansoprazole treatment, while the osteocalcin, DPD, CTX and NTX values were found to be higher after treatment when compared to those at pre- treatment. Conclusions: The results of this study reveal that eight weeks of treatment with 30 mg lansoprazole daily increased the bone turnover markers of CTX, NTX, DPD and osteocalcin in adolescents aged 16-18.
EDUCAÇÃO INCLUSIVA NO ENSINO SUPERIOR PÚBLICO BRASILEIRO
Authors: Alves Lucilene Quintiliano
Published: January 2023

O presente trabalho objetiva revisar a principal legislação que versa sobre a educação inclusiva no ensino superior público brasileiro. Essa modalidade instaurou-se no Brasil após eventos internacionais que marcaram o âmbito educacional do país, refletindo positivamente no seu ordenamento jurídico. A Constituição Federal de 1988 garante que, todos tem direito a educação, a inclusão permite que as pessoas com deficiência tenham esse direito assegurado. As pessoas com deficiência no Brasil passaram por um período de segregação social que acabou influenciando no setor educacional, onde as mesmas estudavam em lugares separados sem participação social. A inclusão desponta para demostrar que a diversidade é importante e deve ser acolhida, todos devem aprender juntos sem qualquer tipo de discriminação.  Os alunos com deficiência têm direito a uma educação de qualidade.
Intraseasonal variability of the South Vietnam Upwelling, South China Sea: influence of atmospheric forcing and ocean intrinsic variability
Authors: Herrmann Marine , To Duy Thai , Estournel Claude
Published: January 2023

Abstract. The South Vietnam Upwelling (SVU) develops off the Vietnamese coast (South China Sea) during the southwest summer monsoon over four main areas: the northern coastal upwelling (NCU), the southern coastal upwelling (SCU), the offshore upwelling (OFU) and the shelf off the Mekong River mouth (MKU). An ensemble of ten simulations with perturbed initial conditions were run with the fine-resolution SYMPHONIE model (1 km inshore) to investigate the daily to intraseasonal variability of the SVU and the influence of the ocean intrinsic variability (OIV) during the strong SVU of summer 2018. The intraseasonal variability is similar for SCU, MKU and OFU, driven to the first order by the wind variability. MKU and SCU are induced by stable ocean dynamics (the northeastward then eastward boundary current) and have very little chaotic variability. The OIV has a stronger influence on OFU. In July, OFU mainly develops along the northern flank of the eastward jet. The influence of OIV is strongest and related to the chaotic variability of the meridional position of the jet. In August this position is stable and OFU develops mainly in the area of positive wind curl and cyclonic eddies north of the jet. The influence of OIV, weaker than in July, is related to the organization of this mesoscale circulation. NCU shows a completely different behavior from the other areas. In the heart of summer, the large-scale circulation formed by the eastward jet and eddy dipole is well established with an alongshore current preventing NCU. In early and late summer, the large-scale circulation is weaker, allowing a mesoscale circulation of strongly chaotic nature to develop in the NCU area. During those periods, the OIV influence on NCU is very strong and related to the organization of this mesoscale circulation: NCU is favored (annihilated) by offshore-oriented (alongshore) structures.
Unsupervised classification identifies coherent thermohaline structures in the Weddell Gyre region
Authors: Jones Dan(i) , Sonnewald Maike , Zhou Shenjie , Hausmann Ute , Meijers Andrew J. S. , Rosso Isabella , Boehme Lars , Meredith Michael P. , Naveira Garabato Alberto C.
Published: January 2023

Abstract. The Weddell Gyre is a major feature of the Southern Ocean and an important component of the planetary climate system; it regulates air-sea exchanges, controls the formation of deep and bottom waters, and hosts upwelling of relatively warm subsurface waters. It is characterized by extremely low sea surface temperatures, ubiquitous sea ice formation, and widespread salt stratification that stabilises the water column. Observing the Weddell Gyre is challenging, as it is extremely remote and largely covered with sea ice. At present, it is one of the most poorly-sampled regions of the global ocean, highlighting the need to extract as much value as possible from existing observations. Here, we apply a profile classification model (PCM), which is an unsupervised classification technique, to a Weddell Gyre profile dataset to identify coherent regimes in temperature and salinity. We find that, despite not being given any positional information, the PCM identifies four spatially coherent thermohaline domains that can be described as follows: (1) a circumpolar class, (2) a transition region between the circumpolar waters and the Weddell Gyre, (3) a gyre edge class with northern and southern branches, and (4) a gyre core class. PCM highlights, in an objective and interpretable way, both expected and under-appreciated structures in the Weddell Gyre dataset. For instance, PCM identifies the inflow of Circumpolar Deep Water (CDW) across the eastern boundary, the presence of the Weddell-Scotia Confluence waters, and structured spatial variability in mixing between Winter Water and CDW. PCM offers a useful complement to existing expertise-driven approaches for characterising the physical configuration and variability of the Weddell Gyre and surrounding regions.
Laboratory measurements of the performances of the Sweeping Langmuir Probe instrument aboard the PICASSO CubeSat
Authors: Ranvier Sylvain , Lebreton Jean-Pierre
Published: January 2023

Abstract. The Sweeping Langmuir Probe (SLP) is one of the
instruments on board the triple-unit CubeSat PICASSO, an ESA in-orbit
demonstrator launched in September 2020, which is flying at about 540 km
altitude. SLP comprises four small cylindrical probes mounted at the tip of the
solar panels. It aims to perform in situ measurements of the plasma
parameters (electron density and temperature together with ion density) and
of the spacecraft potential in the ionosphere. Before the launch, the
instrument, accommodated on an electrically representative PICASSO mock-up,
was tested in a plasma chamber. It is shown that the traditional
orbital-motion-limited collection theory used for cylindrical Langmuir
probes cannot be applied directly for the interpretation of the measurements
because of the limited dimensions of the probes with respect to the Debye
length in the ionosphere. Nevertheless, this method can be adapted to take
into account the short length of the probes. To reduce the data downlink
while keeping the most important information in the current-voltage
characteristics, SLP includes an on-board adaptive sweeping capability. This
functionality has been validated in both the plasma chamber and in space, and
it is demonstrated that with a reduced number of data points the electron
retardation and electron saturation regions can be well resolved. Finally,
the effect of the contamination of the probe surface, which can be a serious
issue in Langmuir probe data analysis, has been investigated. If not
accounted for properly, this effect could lead to substantial errors in the
estimation of the electron temperature.
The Critical Juncture in Aotearoa New Zealand and The Collective Future: Policy Issues in Settler/Invader Colonial Zombiism Found in “Biculturalism”
Authors: Simon Hemopereki
Published: January 2023

This theoretical Kaupapa Māori writing inquiry study seeks to explore the settler colonial nature of Aotearoa New Zealand. The research finds that biculturalism, as a neo-liberal and settler-colonial construct does not provide for either tino rangatiratanga or mana motuhake. Indeed, biculturalism fails to provide for indigenous inclusion and actively suppresses the recognition of mana motuhake. Biculturalism is found to fit Beck’s definition of Zombie Concepts. These are social concepts that are dead and yet kept alive in their use by scholars and society to describe the growing fiction of traditional social institutions and in being kept alive maintain, in this case, settler colonial and colonial power structures. The main argument is that Biculturalism is neoliberal and settler colonial public discourse, that needs to be unpacked and then discarded because it does not provide for tino rangatiranga or mana motuhake.
Recent past, present and hoped-for future of cereal science and plant protein research
Authors: Tömösközi Sándor , Kormosné Bugyi Zsuzsanna , Németh Renáta , Schall Eszter , Farkas Alexandra , Jaksics Edina , Juhászné Szentmiklóssy Marietta , Muskovics Gabriella
Published: January 2023

The fields of science indicated in the title represent centuries old research and development activities of the current department and its legal predecessor institutions, matching the standards, expectations and possibilities of the given era. It is of course impossible to summarize all this in a few pages. A tangential or more detailed description of some areas can be found in other chapters of this issue compiled to review the scientific activities of the department (e.g., in the articles of András Salgó and Ferenc Békés, Zsuzsanna Bugyi et al., Eszter Schallet al.) and in the summary article presenting the department’s food science activities. In our current paper, we attempt to provide a brief overview of research directions and results that, from the 1990s to the present day, have played a decisive role in the activities of the department, including the Cereal Science and Food Quality Research Group, as well as in the development and shaping of its research profile. The years following the regime change were decisive in the lives of all of us. The conditions for education and the cultivation of science changed continuously and significantly, mostly worsening in this transition period. Many people questioned whether it was worth continuing to cultivate the old, traditional areas, or whether we should be more open, modernize and look for new ways, taking advantage of the extremely slow but continuously opening opportunities for building domestic and, especially, international relations, and later for tenders and financing. Progress, development, and openness to new ideas should be essential qualities for an educator and researcher. However, the acquisition of knowledge, experience, and skills takes time, as does the creation and maintenance of the conditions necessary for the cultivation of old or new fields. In this uncertain operating matrix, in the mid-1990s we decided to move towards new areas (modernization of food analysis, automatic and rapid test methods, food safety), while trying to maintain and strengthen the cultivation of traditional fields (such as research related to cereal science and plant proteins, development of analytical methods and instruments) that had gained national and international recognition thanks to the work of our predecessors. In the following sections, a brief summary of grain qualification and related method and instrument developments enabling the examination of typically small amounts of material, research on the qualification of small and pseudocereals and improving their possibilities of use, as well as analytical and product development results for increasing food safety, partially related to the previous topic, is given.
Classics in a new perspective: gluten as a special food safety and analytical challenge
Authors: Bugyi Zsuzsanna , Muskovics Gabriella , Schall Eszter , Török Kitti , Hajas Lívia , Scherf Katharina , Xhaferaj Majlinda , Koehler Peter , Schoenlechner Regine , D’amico Stefano , Poms Roland , Tömösközi Sándor
Published: January 2023

In the last couple of decades, the nutritional role and perception of gluten became controversial. In one hand, gluten proteins play a central role in determining the baking quality of wheat and other cereals. On the other hand, hypersensitivity reactions triggered by gluten in susceptible individuals have become subjects of growing interest. Of these gluten-related disorders, with an estimated global prevalence of 1%, the most important one is celiac disease (CD), which is an autoimmune disorder accompanied by villous atrophy. CD can manifest in a wide range of symptoms, its only treatment option is a lifelong gluten-free (GF) diet. To support compliance to this diet, current EU legislation maximizes the gluten-content of products sold with a GF label in 20 mg/kg. It necessitates accurate quantification of gluten in this low concentration range. The method-of-choice for this purpose is the immunoanalytical-based ELISA (enzyme-linked immunosorbent assay). However, validation of different ELISA methods and the comparability of their results and, consequently, the reliability of the data they provide is problematic. The major goal of this paper is to introduce the analytical and protein chemistry issues behind this problem and the efforts to improve the conditions of the methodology. We are also including the special role of oats in the GF diet in an attempt to provide the widest possible overview of the food safety and analytical challenges represented by gluten.
Elválasztástechnikai módszerek fejlesztése növényi fehérjék és szénhidrátok komplex jellemzésére
Authors: Schall Eszter , Török Kitti , Juhászné Szentmiklóssy Marietta Klaudia , Németh Renáta , Tömösközi Sándor
Published: January 2023

A BME Alkalmazott Biotechnológia és Élelmiszertudományi Tanszékén működő Gabonatudományi és Élelmiszerminőség Kutatócsoportban az elválasztástechnika már hosszú idő óta részét képezi az élelmiszerek, élelmiszer összetevők komplex minőségi értékeléséhez alkalmazott módszereknek. A jelenlegi és jogelőd tanszékünkön dolgozó kollégáink komoly eredményeket értek el az elválasztástechnikai módszereik segítségével például a fehérje és szénhidrát összetétel vizsgálatában, a lipidek (zsírsavak) analízisében, a biogén aminok és aminosavak mennyiségi és minőségi értékelésében, stb. Az alapanyag összetételi meghatározása mellett fontos kérdés volt az egyes molekulák minőségre, technológiai tulajdonságokra gyakorolt hatása. Ezt mindig az adott korban korszerűnek számító eszközöket és módszereket felhasználva volt lehetőség vizsgálni, így gélkromatográfia, nagyhatékonyságú folyadékkromatográfia, gázkromatográfia és elektroforetikus technikák alkalmazása fémjelezte mind a kutatás, mind az oktatás színvonalát. Az elmúlt években a kutatócsoportunkban főként a gabonák minőségével, összetételükkel, technológia potenciáljukkal és élelmiszerbiztonsági szempontú értékelésükkel foglalkoztunk.Ezeknek a területeknek a kutatására a részletes molekuláris szintű (elsősorban fehérje és rost összetételi) vizsgálatok elengedhetetlenné váltak, amelyek kiváló eszközei a modern elektroforetikus és kromatográfiás módszerek. Ezek megfelelő alkalmazása azonban nagy kihívást jelent, mert rutinszerű használatukhoz a legtöbb esetben komoly módszerfejlesztési és/vagy módszeradaptálási, részleges validálási feladatok elvégzése szükséges. A következőkben néhány alkalmazási példán keresztül rövid áttekintést adunk a kutatócsoportunkban az elválasztástechnika területét érintő projektekről és elért eredményeinkről.
Sejthalál a növényvédelemben: az élelmiszer-ellátás biztonságának növelése molekuláris biológiai módszerekkel
Authors: Hajdinák Péter , Szarka András
Published: January 2023

A mezőgazdaság fontos feladata a növények védelme a patogének által kiváltott biotikus és a környezeti hatások által kiváltott abiotikus stresszel szemben. A patogénekkel szembeni védekezés hagyományosan kémiai növényvédő szerekkel történik, amelyek károsíthatják a környezetet és az egészségünket, így komoly igény merül fel arra, hogy ezeket környezetbarát anyagokra cseréljük. Ígéretes biopeszticidek lehetnek a kutatócsoportunk által is tanulmányozott elicitor hatású harpin fehérjék. Ezek a fehérjék valódi patogénfertőzés nélkül váltanak ki immun-választ a növényekben, ezzel fokozva az ellenállóképességüket, valamint egyéb előnyös hatásaikat is leírták már, úgy, mint az intenzívebb növekedés vagy a nagyobb terméshozam. Ezen fehérjék egyelőre nem teljesen tisztázott hatásmechanizmu-sainak jobb megértése segítheti a hatékonyabb biopeszticidek fejlesztését. A Föld átlaghőmérsékletének emelkedésével egyre nagyobb szerep juthat a hőstressz hatására beinduló ferroptózis-szerű sejthalálnak is. Ennek az először 2017-ben leírt sejthalálfolyamatnak a pontos molekuláris mechanizmusa még nem ismert, azonban eredményeink arra utalnak, hogy a reaktív karbonilvegyületek – köztük az akrolein – mediátor szerepet játszhatnak benne. A ferroptózis-szerű sejthalál irodalmi adatok alapján a patogéntámadás hatására bekövetkező hiperszenzitív sejthalálban is szerepet játszik, így a sejthalálfolyamat jobb megértése egyszerre segítheti a biotikus és az abiotikus stresszel szembeni védekezést.
Az élelmiszeripar helyzete és fejlesztési irányai
Authors: Felkai Beáta Olga , Kuti Beatrix Adrienn
Published: January 2023

Magyarországon az élelmiszeripar az 1800-as évektől napjainkig hosszú utat járt be és jelenleg is számos próbatétellel szembesül. Egy rendkívül heterogén, nagy létszámú ágazatról beszélünk, melynek egyedisége és sajátosságai jelentősen befolyásolják a jelenét és a lehetőségeit. Fejlődési lehetősége a hozzáadott érték növelése, a minőségi termékek irányába történő elmozdulás, a hazai, valamint az export piacokon történő helytállás. A fejlődési ütemét meghatározzák az egyes stratégiák, támogatások, szabályozási környezet a K+F+I lehetőségek, a fogyasztói igények és a kapcsolódó edukáció, a rendelkezésre álló alapanyagok elérhetősége és változása, a szigorú élelmiszer-biztonsági követelmények stb. Cikkünkben a 100+10 év az élelmiszertudomány a 240 éves Budapesti Műszaki Egyetemen 2021. november 19-én elhangzott előadás alapján az élelmiszeripar múltját, jelenét és fejlesztési irányait mutatjuk be.
Jornalismo local: estudo da história profissional de jornalistas de São Félix do Xingu e Canaã dos Carajás, na Amazônia Oriental
Authors: Bassi Ingrid , Ferreira Alexandra Manoella Silva
Published: January 2023

A pesquisa dedica-se a sistematizar os processos comunicacionais nas cidades de São Félix do Xingu, Canaã dos Carajás e seus entornos, na região sudeste do Pará, por meio do uso de entrevistas e história oral. A investigação, exploratória objetiva descrever e categorizar os processos de comunicação e a comunicação local da região citada, a partir das categorias: 1- estrutura jornalística, 2- organização profissional da empresa e/ou instituição do terceiro setor, 3- perfil da atuação dos jornalistas, 4-produção jornalística – tipo, formato e gêneros, 5- audiência e periodicidade, 6- saliência local e 7-tematização da informação. Como resultado, é sistematizado o mapeamento dos processos comunicacionais e memórias de comunicadores locais que colaboram com a produção de conteúdo informacional nessas cidades.
A influência da TV regional na formação de um território geomidiático
Authors: Gabriot Rodrigo
Published: January 2023

A construção de um território geomidiático é resultado de um processo configurado pela intervenção da mídia. Neste artigo, mostramos o caso das cidades de Sorocaba e Jundiaí, no interior de São Paulo, que não apresentam relação geográfica, em sentido de espaço, mas que foram constituídas como região a partir da determinação da área de cobertura de uma emissora de TV regional. Essa apropriação midiática desagrada os públicos das duas cidades que avaliam perdas do sentido do local julgando que a emissora privilegia uma cidade em relação a outra. Para tentar amenizar essa diferença apontada, apresentamos quatro tipologias jornalísticas à produção de conteúdo como tentativa dos telespectadores se sentirem mais representados e amenizarem essas diferenças que apontam.
Monsenhor Rios:
Authors: Lacerda de souza Viviam , Da Silva José Antônio
Published: January 2023

Buscamos estudar e coletar dados sobre a vida do Monsenhor Antônio Rodrigues Paiva e Rios, no que tange suas ações em vida e as manifestações de ex-voto que potencializam possíveis milagres. Nos valemos da pesquisa empírica, a observação exploratória das práticas folkcomunicacionais para coleta de dados a fim de inventariar o acervo de peças do núcleo de devoção. Utilizamos a fundamentação teórica e a técnica investigativa na busca dados disponíveis em bibliografias, entrevista, buscadores da internet, relatos de língua corrente e vestígios históricos. Concluímos que este processo de folkcomunicação decorre de manifestações de ex-voto que representam crença e fé em um cenário místico que se valida na construção de subjetividades, onde o imaginário religioso se caracteriza uma fonte de sentidos, vínculos sociais e sentimento de pertença.
Folclore Nu
Authors: De Brites da Costa Andriolli
Published: January 2023

Folclore Nu - Desnudando a Cultura Brasileira é uma iniciativa de divulgação folclórica que consiste em ensaios que reúnem fotografia e nu artístico com mitos e lendas do imaginário popular. Foram quatro ensaios no total, cada um contendo 7 fotos. Em cada uma delas, uma legenda que explica um pouco mais sobre cada mito retratado. O objetivo do projeto foi o de mostrar que o repertório compartilhado do folclore brasileiro pode inspirar não apenas histórias infantis, como amplamente repetido na vulgata, mas qualquer tipo de narrativa. A estética se une à informação, com a possibilidade de transmitir de maneira inovadora fatos pouco conhecidos sobre cada criatura do bestiário nacional.
Parafia unicka pw. św. Mikołaja w Muratynie w świetle osiemnastowiecznych wizytacji kościelnych
Authors: Frykowski Janusz Adam
Published: January 2023

Muratyn to wieś położona w gminie Laszczów, w północnej części powiatu tomaszowskiego w województwie lubelskim. Pierwsza pisemna wzmianka o tej wsi pochodzi z 1430 r., kiedy to książę bełski Władysław I nadał ten majątek Mikołajowi Nieborowskiemu, kasztelanowi sochaczewskiemu. Dokładna data rozpoczęcia funkcjonowania parafii św. Mikołaja w Muratynie nie jest znana, nie ma jednak wątpliwości, że miało to miejsce przed 1687 r. Wiadomo też, że w okresie funkcjonowania tej parafii administracyjnie należała do dekanatu tyszowieckiego. Po przeanalizowaniu protokołów powizytacyjnych pozostawionych przez biskupów chełmskich nakreślono nie tylko wygląd drewnianego kościoła parafialnego wraz z jego wyposażeniem, ale także wygląd prezbiterium i zabudowań pomocniczych. Ponadto oszacowano beneficjum kościelne i jego zmienność w okresie, na którym koncentruje się niniejsza praca naukowa. Nie tylko ustalono dane personalne 5 parafii (proboszczów) pracujących w tej konkretnej parafii, ale również szacuje się liczbę parafian.
Piotr Mazur, Poczet chełmski obrządku łacińskiego
Authors: Kawecki Roman
Published: January 2023

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Ksiądz Benedykt Chmielowski - życie i dzieło Diogenesa Firlejowskiego
Authors: Paszyński Wojciech
Published: January 2023

Celem artykułu jest przybliżenie sylwetki księdza Chmielowskiego, autora pierwszej polskiej encyklopedii powszechnej, znanej jako Nowe Ateny. We wstępie oraz rozdziale pierwszym zwrócono uwagę na istnienie czarnej legendy na temat twórczości Chmielowskiego oraz skąpych danych biograficznych. Rozdział drugi przedstawia możliwe okoliczności nadania imienia, niebagatelne wobec obranej drogi życiowej. W rozdziale trzecim sprostowano błędną atrybucję herbową zaś w czwartym nieścisłości w lokalizacji miejsca narodzin Chmielowskiego, które pokutują w literaturze. Kolejne dwa rozdziały (5-6) omawiają korzenie duchownego i lata edukacji lwowskiej. W rozdziale pt. Na dworze Jabłonowskich poznajemy początki drogi świeżo wyświęconego księdza zaś w rozdziale Firlejów jego codzienne życie – już jako proboszcza. W rozdziale dziewiątym ukazano zmienne koleje fortuny kariery duchownej, by w dziesiątym przedstawić schyłek życia księdza.
Wizytacja kościoła parafialnego w Kosowie z 1844 roku
Authors: Żurek Waldemar W.
Published: January 2023

Prezentowana wizytacja kościoła kosowskiego z połowy XIX wieku daje wystarczająco informacji o administracji, posłudze pastoralnej i uposażeniu Kościoła katolickiego na Kresach Wschodnich, okresu staropolskiego Rzeczypospolitej. Ukazuje także znaczące postacie z ówczesnego życia politycznego i społecznego. Jednak najbogatszą jej częścią są dane dotyczące parafii wizytowanej, od najmniejszego szczegółu czy przedmiotu, po budowle sakralne (z ich wyposażeniem i paramentami do sprawowania kultu), mieszkalne i gospodarcze. Wizytacja ukazuje także troskę o stan moralny i dobra materialne parafii oraz porządek i rozkład liturgii sprawowanej w kościele parafialnym w Kosowie.
ОРГАНІЗАЦІЙНО-ПРАВОВИЙ МЕХАНІЗМ АДАПТАЦІЇ СФЕРИ ОХОРОНИ ПРАЦІ ДО МІЖНАРОДНИХ ТА ЄВРОПЕЙСЬКИХ СТАНДАРТІВ
Authors: Древаль Ю.Д. , Малько О.Д. , Бригада О.В.
Published: January 2023

Проведене дослідження базується на тому постулаті, що міжнародна та європейська інтеграція охоплюють усі найбільш важливі сфери суспільних відносин нашої держави, у тому числі і сферу охорони праці. Власне, і сприй-няття нормативно-правового забезпечення та передового досвіду країн ЄС має розглядатися в якості одного з пріоритетів вдосконалення зазначеної час-тки соціально-трудових відносин. Додатково обґрунтовано положення про те, що процес вдосконалення організаційно-правового механізму адаптації націона-льного законодавства до міжнародних та європейських стандартів має ґрун-туватися на розгалуженому зарубіжному законодавстві та на наявній основі унормування сфери охорони праці в нашій країні.
ІНФОРМАЦІЙНА БЕЗПЕКА УКРАЇНИ : МЕХАНІЗМИ, СУЧАСНІ ВИКЛИКИ ТА ЗАГРОЗИ В УМОВАХ ІНФОРМАЦІЙНОГО ГЛОБАЛІЗМУ
Authors: Леоненко Н.А. , Поступна О.В.
Published: January 2023

Наукова стаття присвячена дослідженню механізмів інформаційної без-пеки України, сучасним викликам та загрозам в умовах інформаційного глобалі-зму. У статті з урахуванням комплексного та доктринального аналізу вказаної проблематики визначено, що важливу роль в досягненні інформаційної безпеки держави відіграє інституційний механізм її забезпечення. Зростання спектру загроз національній безпеці підвищує роль держави в реалізації на практиці си-льної інформаційної політики, заслуговує на особливу увагу суспільства до освітньої сфери, яка безпосередньо впливає на інформаційні технології, і, без-сумнівно, вдосконалення правової регламентації діяльності громадян і держави в інформаційній сфері, що обумовлено сучасними політичними та державними процесами.
ТЕОРЕТИЧНІ АСПЕКТИ ДЕРЖАВНОГО УПРАВЛІННЯ ТА ПРИЙНЯТТЯ ДЕРЖАВНО-УПРАВЛІНСЬКИХ РІШЕНЬ
Authors: Ляшевська О.І.
Published: January 2023

У статті розглянуто питання, щодо ефективності і якості державного управління та прийняття державно-управлінських рішень, які можна досягти лише, якщо дотримуватися певного порядку при їх підготовці, прийнятті та реалізації. Проведено аналіз попередніх наукових досліджень щодо механізмів державного управління з прийняття державно-управлінських рішень у кризових умовах, установлено відсутність єдиної думки в учених із зазначеного актуаль-ного питання та нагальну потребу в проведенні дослідження із цієї проблеми.
Визначено сутність механізмів державного управління щодо прийняття державно-управлінських рішень, а саме: організаційного – у встановленні раці-ональної послідовності дій органів державного управління під час прийняття обґрунтованого рішення, структурно-функціонального – у визначенні оптима-льної структури рішення відповідно до функцій і завдань органів управління, що спільно з іншими механізмами відіграють вагому роль у забезпеченні прийнят-тя обґрунтованого рішення органами державного управління в кризових умо-вах.
Запропоновано шляхи забезпечення прийняття обґрунтованого держав-но-управлінського рішення в кризових умовах завдяки вдосконаленню механізмів державного управління.
ОСОБЛИВОСТІ ДЕРЖАВНОЇ ПОЛІТИКИ СОЦІАЛЬНОГО ЗАХИСТУ НАСЕЛЕННЯ В УМОВАХ ВОЄННОГО СТАНУ В УКРАЇНІ
Authors: Головко В.В.
Published: January 2023

У статті визначено особливості формування та реалізації державної політики соціального захисту населення в Україні. Виокремлено проблемні ас-пекти та суперечності державної політики соціального захисту населення в сучасних умовах. Обґрунтовано напрями трансформації державної політики соціального захисту населення в умовах воєнного стану в Україні.
A Comprehensive Review: Drug Interactions and Polypharmacy
Authors: Fatima Dua , Waseem Faiza , Riaz Tehseen , Bashir Irfan , Mehboob Tooba
Published: January 2023

The aim of our study is to identify the drug interactions due to polypharmacy. A medication interaction happens when the impact of one medication is changed in the presence of other. The effect of interfacing drugs can be controlled securely without causing any harm to the patient through cautious checking and dose change. Polypharmacy is portrayed as "the utilization of various medicines or potentially the combination of a greater number of prescriptions that are clinically prescribed, leading to superfluous medication use. Polypharmacy includes the number of medicines taken by the patient, the provision of at least one wrong medicine, or a combination of both, which can expand the danger for adverse medication occasions, underutilization of drug, and redundancy of medication. Polypharmacy Management is an entire framework approach that upgrades the consideration of multimorbid patients through amplifying advantage while decreasing the dangers of improper polypharmacy. The review and assessment of prescription is an intercession that should be ordinarily performed by clinical drug specialists to improve the drug therapy results, medicine’s adverse impact and guaranteed the use of ideal prescription. There should be a proper and strong role and communication of physicians, pharmacists, and patients in society, especially in developing countries. The potential risk factors should be identified, like the interaction of diet with the drug therapy so that adverse reactions can be identified and avoided.
Surge Ahead or Perish in Humiliation
Authors: Dr. Shujaat Hussain
Published: January 2023

The first scientist and bachelor of India became the 11th President of the largest democratic multi-cultural country whose full name contains 31 letters and five words –Avul Pakir Jainulabdeen Abdul Kalam. During his tenure he was popularly called People’s President. Everybody wishes to know his realm of achievements in the field of scientific world –space, defense and nuclear. He made significant contribution in the indigenous Satellite Launch Vehicle (SSLV-III) which successfully injected the Rohini satellite in the near earth orbit in July 1980 and made India an exclusive member of Space Club, will it transform future of India? Mother India’s aspiration accomplished when a star twinkles in the temple town, Rameswaram, Tamil Nadu on October 15, 1931. This is the glittering star that the world sees on the forehead of the Mother. She feels pride in wearing this star on her forehead. His deed has brought honour to his Mother. Dr. Kalam could do with his Mother’s blessings. He says that surge ahead as a developed nation or perish in perpetual perplexity of poverty, hunger and humiliation. His idea is all about breaking away from the forces that would prefer us to remain a nation of a billion people selling cheap labour and raw materials and providing a large market for goods and services of other nations. We have all the resources we need such as man power, talent, natural bounty or other assets. India is truly and naturally blessed with means to flourish. No reason is left to face poverty, hunger and humiliation. Sometimes it puzzles Dr. Kalam: “Who am I to write about this capacity of India to realize its destiny a developed nation?” A gifted son packed with inspirational spirit for the betterment of India, devoted scientist who has heightened the peak of the glory, missile man who has laid the foundation of the visionary roadmap to build India a developed country by 2020. He lives in every heart and soul of the budding minds who are to be an ingredient of the mighty and prosper India. O my dear Bharat Ratna! The entire nation salutes your indubitable integrity, sincerity, humility, magnanimity, and virtuosity. It is immaterial if you have acquired nothing, built nothing, and possessed nothing –no family, sons, and daughters. Look at India. It is, by far, yours. One billion people belong to your family. Young boys and girls are your sons and daughters. You have already attained fatherly figure.
Study of violence against women
Authors: Dr Snigdha Jha
Published: January 2023

In the early 90s, the Violence in the cases of dowry was the crux, and later it gave vent to the other sort of violence against women as domestic violence and wife battering as per its incessant giant like growing form. In the last two decades, domestic violence has captured the attention of all sorts of social and judicial authorities. It is crucial to gauge the structure of violence against women in India through the generic pattern, which remains more or less similar across the world. The narrative of victimhood is vital to get the proper solution of all sorts of violent acts against women in society. In Hyderabad, India has women police for such cases, and there are many statistics that we need to understand in the context of this matter of violence against women. The active collaboration between the NGOs and the government authorities is indispensable to control such criminal arenas. Family and friends can do work at a deeper level to eradicate this problem to make the society free from the clutches of domestic violence or wife battering. The discrimination of caste, race, or between man and women can be traced in the religious scriptures.