bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk Factors Associated with Myocardial Infarction Among Patients at Uganda Heart Institute, Mulago National Referral Hospital in Uganda
Authors: Javila Bukomeko , Atuhaire Leonard , Bosco Asiimwe John , Tumusiime Sula , Dick Nsimbe
Published: February 2025

Background
Myocardial infarction (MI) is a leading cause of death globally, with ischemic heart disease (IHD) accounting for 9.1 million deaths in 2019. In Uganda, cardiovascular diseases, including MI, are contributing to an increasing burden on the healthcare system. The prevalence of MI in the country is not well-documented, though reports suggest a growing incidence, particularly in urban areas. The objective of this study was to investigate the factors associated with myocardial infarction at Mulago Heart Institute, Uganda.
Method
This study utilized data from 615 patients who registered at the Uganda Heart Institute between January 2015 and December 2019. A logistic regression model was employed to identify the factors associated with myocardial infarction.
Results
58.6% of the patients had experienced myocardial infarction. Significant factors found to influence the occurrence of myocardial infarction included age over 64 years (OR = 6.369; 95% CI = 2.27–17.08; p = 0.001), female gender (OR = 0.325; 95% CI = 0.13–0.79; p = 0.013), rural residence (OR = 0.114; 95% CI = 0.05–0.24; p = 0.001), obesity (OR = 1.671; 95% CI = 3.77–5.90; p = 0.031), overweight (OR = 0.775; 95% CI = 4.31–7.04; p = 0.025), hypertension (OR = 8.124; 95% CI = 4.05–16.29; p = 0.001), diabetic status (OR = 0.080; 95% CI = 0.04–0.16; p = 0.001), inactive physical activity (OR = 19.486; 95% CI = 1.72–3.53; p = 0.001), tobacco use (OR = 1.608; 95% CI = 4.30–5.24; p = 0.001), and alcohol consumption (OR = 7.073; 95% CI = 0.81–1.61; p = 0.016). High blood pressure was also a significant factor influencing the likelihood of myocardial infarction, with hypertensive patients showing significantly higher odds (OR = 8.124; 95% CI = 4.05–16.29; p = 0.001) compared to those with normal blood pressure.
Conclusions
These findings underscore the importance of addressing these risk factors through public health interventions, particularly focusing on hypertension management, promoting physical activity, and reducing tobacco and alcohol consumption especially in rural area, to mitigate the growing burden of myocardial infarction in Uganda.
Impressum und Inhaltsverzeichnis
Authors: Jebens Holger
Published: February 2025

Impressum und Inhaltsverzeichnis
Detection of Tetrachlorobutadiene Isomers Using Density Functional Theory Methods
Authors: Fatema Kaniz
Published: February 2025

The study aims to build upon previous research by incorporating Density Functional Theory (DFT), specifically using the B3LYP functional, to improve the computational methodology for analyzing chlorobutadiene (TCBD) compounds. DFT is chosen for its ability to account for electron correlation effects beyond the mean-field approximation, a limitation found in earlier approaches such as the Hartree-Fock (HF) method. By incorporating electron correlation, DFT provides a more accurate description of molecular properties, making it highly suitable for analyzing complex molecular structures like those found in chlorobutadienes. The methodology adopted in the study comprises four key steps. First, the molecular structure of each isomer was created. Next, the geometry of the isomers was optimized using DFT methods to ensure the most stable configurations for further analysis. The third step involved computing the vibrational frequencies of the molecules using the B3LYP functional, with different basis sets applied depending on the isomer under study. Finally, the simulated infrared (IR) spectra generated through DFT were compared with existing data from the literature to validate the findings and assess the accuracy of the computational model. The study focuses on nine different Tetrachlorobutadiene (TCBD) isomers, each with unique configurations of hydrogen and chlorine atoms. These structures were visualized using Molden software, and the IR spectra for each isomer were obtained using DFT, specifically the B3LYP and B3LYP-D3BJ functionals. The analysis of the IR spectra revealed characteristic peaks corresponding to various functional groups within the TCBD molecules. Notable vibrational modes include C-Cl stretching, C=C stretching and bending, and C-H stretching and bending, which are essential in identifying the chemical composition of the isomers. A comparative analysis was conducted between DFT and the previously employed Hartree-Fock (HF) method.
DanceQ: High-performance library for number conserving bases
Authors: Schäfer Robin , Luitz David J.
Published: February 2025

The complexity of quantum many-body problems scales exponentially with the size of the system, rendering any finite-size scaling analysis a formidable challenge. This is particularly true for methods based on the full representation of the wave function, where one simply accepts the enormous Hilbert space dimensions and performs linear algebra operations, e.g., for finding the ground state of the Hamiltonian. If the system satisfies an underlying symmetry where an operator with a degenerate spectrum commutes with the Hamiltonian, it can be block-diagonalized, thus reducing the complexity at the expense of additional bookkeeping. At the most basic level required for Krylov space techniques (like the Lanczos algorithm), it is necessary to implement a matrix-vector product of a block of the Hamiltonian with arbitrary block-wavefunctions, potentially without holding the Hamiltonian block in memory. An efficient implementation of this operation requires the calculation of the position of an arbitrary basis vector in the canonical ordering of the basis of the block. We present here an elegant and powerful, multi-dimensional approach to this problem for the U(1)U(1) symmetry appearing in problems with particle number conservation. Our divide-and-conquer algorithm uses multiple subsystems and hence generalizes previous approaches to make them scalable. In addition to the theoretical presentation of our algorithm, we provide DanceQ, a flexible and modern – header only – C++20 implementation to manipulate, enumerate, and map to its index any basis state in a given particle number sector as open source software under https://DanceQ.gitlab.io/danceq.
CAREER DECISION OF HIGHER SECONDARY STUDENTS IN RELATION TO THEIR SELF - EFFICACY
Authors:   Ph.D. Research Scholar, Department of Education, Bankura University, Bankura, West Bengal., Sau Suchismita , Mandal Udayan ,   Assistant Professor, Department of Education, Bankura University, Bankura, West Bengal.
Published: February 2025

Career decision is defined as the beliefs in ones capabilities to successfully engage in the activities of selection and planning of occupation. The objectives of the paper are to measure career decision of higher secondary level students and how self-efficacy helps the students in deciding a career. In the present study, career decision and status of self-efficacy is measured by the scores obtained through the self-constructed scales by the investigator. It is a descriptive correctional study. Through the hypothesis testing, the results found out positively significant correction in regards of location and gender wise. The research findings show that positive results regarding career decision, high self efficacy students are very much helped for choosing a suitable career. The research may recommend to the different state higher secondary or higher education students and different government organizations must orient students to enhance career related decision.
AETIOLOGICAL FACTORS FOR H.C.C- EXPERIENCE AT TERTIARY CARE CENTRE OF NORTHERN INDIA
Authors:   Department of Medical Gastroenterology and Gynaecology & Obstetrics, PGIMS, Rohtak, Haryana, India., Malhotra Parveen , Malhotra Vani ,   Department of Medical Gastroenterology and Gynaecology & Obstetrics, PGIMS, Rohtak, Haryana, India., CF Bibin ,   Department of Medical Gastroenterology and Gynaecology & Obstetrics, PGIMS, Rohtak, Haryana, India., Senti Senti ,   Department of Medical Gastroenterology and Gynaecology & Obstetrics, PGIMS, Rohtak, Haryana, India., Singh Harman ,   Department of Medical Gastroenterology and Gynaecology & Obstetrics, PGIMS, Rohtak, Haryana, India., Kumar Sandeep ,   Department of Medical Gastroenterology and Gynaecology & Obstetrics, PGIMS, Rohtak, Haryana, India.
Published: February 2025

Hepatocellular Carcinoma (HCC) is one of the most common malignant tumours in the world. It is a heterogeneous group of a tumour which varies in risk factor, genetic and epigenetic alteration event. The mortality rate due to it is increasing with time. The various risk factors include hepatitis B &C viruses, alcohol, metabolic syndrome including diabetes mellitus, chemicals, and inborn and acquired metabolic disease. HCC is closely associated with hepatitis B and C virus because liver injury caused by viral factor affects many cellular processes such as cell signalling, apoptosis, transcription, DNA repair which in turn induce important effects on cell survival, growth, transformation and maintenance. The molecular mechanisms of hepatocellular carcinogenesis vary depending on different factors thus leading to different mechanisms associated with these tumours. Our study shares the experience of various aetiological factorsresponsible for HCC at tertiary care centre of Northern India.
AWARENESS AT NURSING LEVEL- BOON FOR HCV MANAGEMENT
Authors:   College of Nursing, PGIMS, Rohtak, Haryana., Rani Babita , Rani Jyoti ,   College of Nursing, PGIMS, Rohtak, Haryana., Hemwati Hemwati ,   College of Nursing, PGIMS, Rohtak, Haryana., Singh Vazir ,   College of Nursing, PGIMS, Rohtak, Haryana., Rathee Rathee ,   College of Nursing, PGIMS, Rohtak, Haryana., Malhotra Parveen ,   College of Nursing, PGIMS, Rohtak, Haryana.
Published: February 2025

Introduction: Hepatitis C virus (HCV)causes chronic infection in majority of cases but in few can also present as acute hepatitis and has already impacted170 million people worldwide which amounts to 3% of total world population and they are atfuture risk of developing cirrhosis and liver cancer.

Aim: To assess the effectiveness of self-instructional module on knowledge and awareness regarding prevention and control of hepatitis C among B.Sc. Nursing 4th year students of College of Nursing at PGIMS Rohtak.

Methodology: The study was done on 70 students of B.Sc. Nursing 4th year students of College of Nursing, PGIMS Rohtak from 1st Jan.2020 to 8th Feb.2020, to assess the effectiveness of self-instructional module on knowledge and awareness regarding preventive measures of HCV.

Results: The administration of self-instructional module in posttest leads to more knowledge in students about HCV, thus enabling them, to take care of themselves, their family and patients in better way. There is partial significant association between knowledge with selected demographic variables.
RESISTANT COCOA GENOTYPES SELECTED AGAINST PHYTOPHTHORAMEGAKARYA IN THE RECIPROCAL RECURRENT SELECTION PROGRAM
Authors:   Cacao Genetic Improvement Laboratory, CNRA Research Station of Divo, Divo, Cote dIvoire., Caudou Trebissou Inago , Mathias Tahi Gnion ,   Cacao Genetic Improvement Laboratory, CNRA Research Station of Divo, Divo, Cote dIvoire., Coulibaly Klotioloma ,   Cacao Phytopathology Laboratory, CNRA Research Station of Divo, Divo, Cote dIvoire.
Published: February 2025

Black pod rot of cacao caused by stramenopiles of the genus Phytophthora can lead to up to 60% yield losses in endemic regions of Cote dIvoire. To reduce the field incidence of this disease, genetic control emerges as an alternative solution capable of providing resistant varieties to farmers.This study was conducted on 93 cocoa genotypes and three reference controls with Variables sensitivities. The inoculation technique used was that described by Nyasse, and the strain utilized was a highly aggressive isolate of P. megakarya. The Blaha scale was applied to assign infection scores to each leaf disk.The results of hierarchical cluster analysis on principal components (HCPC), followed by Correspondence Factor Analysis (CFA), revealed that the genotypes were divided into five homogeneous groups based on infection score frequencies. Twenty-eight genotypes in cluster 1 were classified as highly resistant to P. megakarya. Twenty other genotypes belonging to cluster 2 were classified as resistant to the pathogen. These genotypes will be used as progenitors in the genetic improvement program to create and disseminate resistant descendants against this phytopathogen.
A RARE CASE REPORT : MACULAR HAEMORRHAGE AS A COMPLICATION OF MEGALOBLASTIC ANAEMIA
Authors: Rai Garima , Kr Annu Bibhash , Verma Santosh , Shandilya Mahima
Published: February 2025

We report a case of 17-year-old female patient with sudden, painless, non progressivediminished vision in both eyes (L>R)(best corrected visual acuity in right eye- 6/18 and left eye - 3/60) . She was on a strict vegetarian diet for a long time. The ophthalmological evaluation revealed bilateral pallor and retinal haemorrhages. She was diagnosed to have severe megaloblastic anaemia secondary to nutritional deficiency with associated anaemic retinopathy.After treatment with intramuscular B12 supplementation, dramatic resolution of retinal haemorrhages and improvement in visual acuity was observed after 6 weeks .This case documents the rare occurrence of bilateral sub internal limiting membrane haemorrhages with megaloblastic anaemia with thrombocytopaenia and other retinal features of anaemic retinopathy.
MONETISATION CHALLENGES AND GROWTH STRATEGIES IN INDIAS OTT MARKET: AN ANALYSIS IN 2023
Authors:   Research Scholar, Research Department of Commerce, University of Mumbai, Kalina, Santacruz, Mumbai., Vora Abhishek , Thakkar Kinnarry ,   Research Guide, Professor, Department of Commerce, University of Mumbai, Kalina, Santacruz, Mumbai.
Published: February 2025

This study critically assesses monetization challenges and growth strategies of Over the Top (OTT) platforms in Indias growing $5B+ market in 2023. The research identifies price sensitivity, fragmented payment systems, and intense competition using a cross-sectional survey of 120 financial experts from the top OTT firms. The findings display the dominance of hybrid revenue models, and the key to regional content is diversification. The study results demonstrate how revenue strategies depend heavily on regulatory frameworks and economic factors. As a contribution to this academic gap, this research provides actionable insights for OTT policymakers to help monetize Indias heterogeneous digital landscape, fuelling the growth of the Indian OTT market.
THORACO-OMPHALOPAGUS CONJOINED TWINS: CASE REPORT
Authors:   Gynecology-Obstetrics Department Military Training Hospital Mohammed V Rabat Morocco., Guelzim Khalid , Bouhtouri Yassine ,   Gynecology-Obstetrics Department Military Training Hospital Mohammed V Rabat Morocco., Benali Saad ,   Gynecology-Obstetrics Department Military Training Hospital Mohammed V Rabat Morocco., Kouach Jaouad ,   Gynecology-Obstetrics Department Military Training Hospital Mohammed V Rabat Morocco.
Published: February 2025

Conjoined twins are an extremely rare form of monozygotic twinning, with an estimated incidence of between 1 in 100,000 and 1 in 250,000 live births, and are rarely encountered by obstetricians. Prompt diagnosis and management are essential, as around 70% of conjoined twins die within 48 hours of birth or present with lethal congenital malformations. We report the case of a thoraco-omphalopagus twin pregnancy terminated at 13 weeks amenorrhea.
Influence of Extraction Time and Circadian Rhythm on the Content, Chemical Composition and Antifungal Activity of the Essential Oils from Callistemon viminalis (Myrtaceae) Leaves
Authors: C. de Matos Chrystiaine Helena , L. Carvalho Paloma Carolina , O. Botelho Alex , R. Forim Moacir , P. Matos Andreia , O. S. Cunha Gracielle , F. Alves Cássia Cristina , de M. Cazal Cristiane
Published: February 2025

The present study aimed to evaluate the influence of the circadian rhythm and hydrodistillation
time on the content and chemical composition of the essential oils (EOs) from the leaves of
Callistemon viminalis, as well as their antifungal activity against Colletotrichum gloeosporioides,
Colletotrichum karstii and Botrytis cinerea. The EOs from C. viminalis leaves showed yields
ranging from 0.54 to 1.67%, with eucalyptol identified as the predominant component in all
samples. During the circadian rhythm, samples collected at different times exhibited variations
in chemical composition. The EOs from leaves collected at 6 a.m. and 6 p.m. showed higher
antifungal potential against B. cinerea, with a 100% inhibition of mycelial growth (500 µL mL-1),
while samples from 6 a.m. and 12 p.m. showed effects against C. gloeosporioides with inhibition
percentages of 52.3 and 55.9%, respectively (500 µL mL-1). The 6 a.m. sample showed the best
inhibition potential against C. karstii, with an inhibition percentage of 68.9% at a concentration
of 600 µL mL-1.
RAINER MARIA RILKE’S POETRY IN THE INTERPRETATION OF GUNTHER ANDERS AND HANNAH ARENDT AND THE CRISIS OF FUNDAMENTAL ONTOLOGY
Authors:   St. Petersburg University of Humanities and Social Sciences, LOSTCHEVSKY KIRILL ,   Russian Christian Academy for Humanities named after Fyodor Dostoevsky
Published: February 2025

The article examines the ontological problems posed in the work of G. Anders and H. Arendt “The Duin Elegies of Rilke”, which is considered in the context of the evolution of M. Heidegger’s philosophical ideas. In the 30s of the twentieth century, Heidegger’s philosophy underwent a significant shift associated with the transition from the construction of a phenomenologically and anthropologically oriented ontology to the thinking of being, which proceeds from its original openness and follows the guiding thread of language. The interest that the text of Anders and Arendt presents in this regard is that it can also be seen as a statement of the unproductiveness of the phenomenological method of posing and solving ontological problems, the rejection of attempts to reveal the meaning of being based on explication of the structure of human existence, and the shift of emphasis to comprehension of the essence of language and interpretation of poetic speech. In the work under study by Anders and Arendt, two plans of philosophical analysis of Rilke’s poetic text are revealed: first, arguments about poetic thinking as a way of revealing artistic and philosophical truth, and, secondly, a meaningful interpretation of the ideas that are articulated in this poetry. It is noted that Anders and Arendt’s appeal to the poetry of R. M. Rilke and the turn in Heidegger’s thinking could be dictated by similar motives: the search for promising ways to overcome the emerging crisis of the fundamental ontological program. Moreover, as a result of the research, it is suggested that the work of Anders and Arendt, published in 1930, to a certain extent outstrips and anticipates the future direction of Heidegger’s reflections, and in shifting the focus of his research interest in language and poetic creativity are realized the interpretative possibilities that were outlined by Anders and Arendt.
PHENOMENOLOGY OF THE PLASTIC IMAGE: HOW IS A PHILOSOPHICAL PARABLE POSSIBLE IN SCULPTURE?
Authors:   Kuban State Technological University, APOLLONOV IVAN ,   Kuban State University
Published: February 2025

The article examines the question posed in the title, which implies the consideration of sculpture as a method of sense making by plastic means, revealing the truth of being in spatial form. The study of the phenomenological perspective of this method is built upon I. Kant’s conception of art as a free play of genius, based on reason. The apparent contradiction between the spontaneity of the subjective assumption of an image, which implies the impossibility of its being deduced, and its rationality, assuming an extra-subjective universalism of meaning, is resolved based on the F. Schelling’s doctrine of creation as “a pure being who escapes to any thought” (unvordenkliche) act of the subject positing something in the conceptual horizon of the logical possibilities of its existence uncertainty. The act of vivid imagination and the coherent process of creating art work presupposes not only the subjective arbitrary will of the artist, but also the “intelligence of vision,” connecting the intentional act constituting the image and the counter-intentional act, in which the image created manifests its own teleology, clarifying and elaborating the author’s idea. The sculptor’s consciousness acts as a kind of tuning fork, capable of capturing the accuracy of the sound of the image, its harmony with aesthetic sensibility. At the same time, the expressiveness of the art work, its beauty is the non-verbal aspect of meaning, capable of signifying and expressing the author’s vision of the ideological depth of the chosen theme, which allows the sculptor to create original philosophical parables that heuristically complement verbal forms of thought. These provisions are considered in the context of the sculptural series “Masque Theatre” created by Alexander Apollonov, whose plastic images show various scenarios and complex drama of the relationship between the subject and his personal objectifications, manifested in masks-personalities.
TO LOSE THE MEANING OF MUSICALITY. WHAT IS THE PLACE OF MUSIC IN A WORLD SATURATED WITH AUDIO RECORDINGS?
Authors:   Nantes Université, LANG PATRICK
Published: February 2025

“Listening to music” and “listening to sound recordings” have become perfectly synonymous in our society. The aim of this paper is to question the legitimacy of this supposed equivalence, which almost all listeners have taken for granted. Our sonic universe is saturated with recorded sounds: what space does it leave to music? What reasons could justify a radical distinction, or even opposition, between the exposure to recorded sounds and musical activity in the strict sense of the word? According to tried and tested phenomenological method, through conscious attention to what appears, we return “to the matters themselves”: namely, the conditions under which sonorities can become music. After a first, introductive part reflecting the exceptional marginality of recording in mankind’s musical history, the second part of the study sketches a phenomenological description of a genuine musical process; the final part examines the consequences of sound registration with regard to such a process and to various aspects of music making and listening to music. It is thereby shown that recordings are by no means a vector of democratizing musical culture.
MEINONG: A NEW READING OR IMMERSION IN TRADITION
Authors:   Institute of Philosophy and Law, Siberian Branch of the Russian Academy of Sciences, TSELISHCHEV VITALY
Published: February 2025

This article is a response to A. Patkul’s review of my translation of D. Jacquette’s book “Alexius Meinong, the Shepherd of Non-Being.” I disagree with reviewer’s opinion on a number of issues. One of the objections is that A. Patkul proceeds from the implicit (and sometimes explicit) opposition of analytical and continental philosophy when considering the contents of a book written by an analytical philosopher, and moreover translated by an analytical philosopher. This attitude is manifested by him in two trends. Firstly, it is an emphasis on the already well-known sides of the Meinong’s theory of objects, which is rather of historical and philosophical interest, tending more to repeat the “Brentanian” roots and phenomenological aspects of Mining. Actually, the application of Meinong’s ideas to modern philosophical problems, which is the subject of Jacquette’s book, is practically ignored. Secondly, reviewer’s claims to the terminological decisions of the translator turn out, in addition to trivial typos, to be the result of all his desire to keep Meinong in the bosom of often scholastic terminology, with the recommendation to make do with Latin tracing paper. From my point of view, despite the well-known quirkiness of the terminology of Meinong himself, when translating, one should strive to convey the meaning in terms understandable to the reader.
Studying the impact of rainfall and LULC changes in the reservoir water level of the Hatia dam, Ranchi, India
Authors: Kumar Sneh , Singh Vivekanand , Kumar Ved Prakash , Thendiyath Roshni
Published: February 2025

This study aimed to analyse the pattern of rainfall and land use land cover (LULC) changes and their impact on the water level of the Hatia dam, a crucial source of the water supply for Ranchi city in Jharkhand, India. High-resolution daily-gridded rainfall and temperature data from 1991 to 2023 were collected from IMD Pune and analyzed using Mann–Kendall and Sen's slope estimator. The results showed a significant decline in annual, monsoon, post-monsoon, and winter rainfall, while pre-monsoon rainfall increased during the study period. The Google Earth Engine was used to observe LULC changes at 5-year intervals. The analysis revealed significant changes in the waterbody, built-up, forest cover, barren land, and agriculture before and after the monsoon. The analysis show that during the pre-monsoon season, the waterbody decreased from 8.68 to 4.94%, while the built-up area increased from 2.71 to 11.08%. Similar trends were observed during the post-monsoon season, with the waterbody decreasing from 10.06 to 7.3% and the built-up area increasing from 2.74 to 11.27%. It is observed from the rainfall analysis that the annual rainfall is decreasing from 1,561 to 703 mm and the reservoir surface area has also decreased from 126.31 to 37.44 ha. The findings highlight the need for sustainable water management strategies.
Synergistic effect of electrooxidation and anaerobic digestion of waste-activated sludge for microbial inactivation
Authors: Cano Anaid , Barrios Jose Antonio , Maya C. , Pérez M. , Román A. , Jiménez B.
Published: February 2025

Electrochemical pretreatment and anaerobic digestion (AD), as well as a combination of both processes, were studied for the treatment of waste-activated sludge (WAS) to evaluate microbial inactivation, for faecal coliforms, Salmonella spp., bacteriophages, and helminth eggs. Electrooxidation (EO) of WAS was performed in a commercial cell with boron-doped diamond electrodes. 1 L of WAS (3% total solids) was fed to the electrochemical cell in recirculation mode. The conditions tested were 19.3 mA/cm2, 30 min, and 3.8 L/min. For AD tests, raw and pretreated WAS were digested in an OxiTop® OC 110 apparatus for 15 days. Inactivation of faecal coliforms, Salmonella spp., and bacteriophages reached more than 5 logs when EO was combined with AD. In contrast, EO alone did not inactivate these parameters, while AD achieved eliminations around 3 logs. Moreover, the combined process inactivated 91% of the initial viable helminth eggs, considerably higher than AD (29%) and EO (0%). The results suggest that EO separates extracellular polymeric substances and segregates particles, including microorganisms, that are exposed to environmental factors (e.g., volatile fatty acids or ammonia) during AD, showing a synergistic effect.
Avaliação da usabilidade de um aplicativo para pacientes com sepse em unidades de terapia intensiva
Authors: Ataide Brandão Gustavo , Silva Maíris Feijó da , Brito João Gabriel Gouveia de Souza , Souza Claudinalle Farias Queiroz de , Silveira Maria Mariana Barros Melo da , Figueirêdo Thaisa Remigio
Published: February 2025

Objetivo: Este estudo teve como objetivo avaliar a usabilidade de um aplicativo para a Sistematização da Assistência de Enfermagem em pacientes com Sepse nas Unidades de Terapia Intensiva (UTI).  Métodos: Trata-se de um estudo metodológico de abordagem quantitativa, que envolve dois processos: a construção de um aplicativo e a avaliação da usabilidade deste instrumento. A amostra do estudo foi por conveniência, composta por enfermeiros das UTIs adultos de um complexo hospitalar universitário. O instrumento utilizado para a avaliação da usabilidade foi o System Usability Scale (SUS), adaptado em uma escala Likert que busca avaliar, principalmente, a aprendizagem, a eficiência, e a satisfação, tendo como um escore bom >68.  Resultados: Os resultados demonstraram que os profissionais consideraram a ferramenta aceitável, com boa pontuação no instrumento de qualificação. Após a utilização e a avaliação do aplicativo através da escala Likert SUS, obteve-se um escore de 83.18 na classificação. Conclusão: Isso confirma a usabilidade e utilidade do aplicativo, indicando sua viabilidade para integração nos sistemas de prontuário eletrônico em unidades hospitalares. Este avanço é crucial para pesquisas em Tecnologias da Comunicação e Informação na Enfermagem, abrindo novas possibilidades no empreendedorismo para melhorar a assistência e gestão de saúde para pacientes, equipes e instituições.
Significant Role of Polymers in the Field of Surgery
Authors: Kulshrestha Niharika
Published: February 2025

Polymers have unique features which make their wide application. The unique features of polymers such as high flexibility, durability, mechanical stability, light weight, easy to use, easily available, low cost etc. make them useable in various industrial, homely, electrochemical, electrical, electronics, medical, biomedical, surgery and food packaging. This chapter mainly focused on the application of polymers in the field of surgery. In the older methods, absence of polymers was facing limitations like decreased mechanical stability and low adherence to tissue surface. This chapter also discussed that different shape memory polymers can be used in surgery.
EXAMINING MALAYSIA'S LOW-INCOME HOUSING ENVIRONMENT: A QUANTITATIVE STUDY OF THE LOW-INCOME HOUSING ENVIRONMENT'S IMPACT ON RESIDENTS' ATTITUDES AND QUALITY OF LIFE
Authors: Alias Zuraini , Abdol Ghani Mohd Reza , Saad Mazni , Abdullah Mokhtar , Mohamed Mohan Noor Malinda
Published: February 2025

In Malaysia, the burgeoning population has increased the demand for affordable housing, leading to the establishment of Low-Income Housing Programs (PPR) to assist the B40 income group. Despite the noble intentions, PPR communities face challenges, especially with residents' behaviours such as improper waste disposal, which exacerbate cleanliness and safety issues. These behaviours negatively affect living conditions and contribute to an increase in crime rates within these areas. Numerous studies have investigated how the PPR environment impacts residents' quality of life, highlighting the prevalence of detrimental living conditions. Although extensive research has been conducted on the structural and operational aspects of PPR housing, more studies are needed to explore the direct impact of residents' attitudes on their quality of life. This study aims to bridge this gap by examining the intermediary role of residents' attitudes towards their environment and its subsequent effect on their quality of life. Utilizing data from a survey conducted in five states with PPR residents and employing the Partial Least Squares (PLS) method, the study found significant correlations between the PPR environment, residents' attitudes, and their quality of life, underscoring the crucial role of attitude in shaping the living experiences of PPR inhabitants.
SUSTAINING THE ENVIRONMENT THROUGH E-WASTE RECYCLING
Authors: Tun Ismail Wan Nor Azilawanie , Sulaiman Sabri , - Islahuddin
Published: February 2025

Millions of electrical and electronic devices are thrown away annually due to items breaking or needing to be updated. These discarded electronics are referred to as e-waste. Using an online survey with a quantitative approach, this study examined the interrelationships among knowledge of hazards of e-waste, attitude towards e-waste recycling, pro-environmental intention, and e-waste recycling behaviour among households in Kelantan, Malaysia (n=300). Partial Least Squares Structural Equation Modeling (PLS-SEM) was used to examine the relationships between the variables. The findings of this study reveal a favourable relationship between knowledge of the hazards of e-waste and attitude towards e-waste recycling with pro-environmental intentions. Furthermore, an appropriate relationship was discovered between the intention to e-waste recycling behaviour. The study provides theoretical insights and practical suggestions relevant to regulators and practitioners, focusing on encouraging e-waste recycling to support environmental sustainability.
SIMULATION MODEL OF GREEN OPEN SPACE ON MICROCLIMATE PERFORMANCE IN TROPICAL COASTAL AREA
Authors: Widyasamratri Hasti , Karmilah Mila , Abdi Musyafiq Afrizal , Kusumawanto Arif , Mohd Noor Norzailawati
Published: February 2025

This research aimed to simulate scenario of green open space to mitigate heating within microclimate performance. It also optimized the composition of the built environment's surface to reduce urban heating. A numerical model was simulated using ENVI-met, and spatial analysis was conducted with ArcGIS software. Three different scenarios were established to propose solutions for heating reduction. Simulation showed that a balanced composition between buildings and vegetation resulted in air temperature decrease of 2.45°C to 3.31°C compared to no-greenery simulation. Meanwhile, when compared to the existing situation, hybrid greenery achieved a 3.50°C air temperature decrease. This research offered valuable insights into the urban environment by prioritizing landscape design, focusing on buildings and the composition of green open space in surrounding areas
EXTRINSIC AND INTRINSIC MOTIVATION OF URBAN TOURISTS TO TRAVEL WITH PUBLIC TRANSPORT FOR LEISURE: ANALYSIS OF TRIPADVISOR REVIEWS
Authors: Kamarudin Nabihah , Sinniah Gobi Krishna , Syed Jaafar Syed Muhammad Rafy , Yusof Janatun Naim
Published: February 2025

Analysis of online reviews on tourism studies has been widely used among researchers. Transportation plays an important role and acts as a medium to connect tourists towards tourist destinations. There is still a lack of studies concerning their reasons for using public transport. Hence, this study addresses to investigates the extrinsic and intrinsic motivation of tourists to use public transport in Kuala Lumpur through TripAdvisor. This research analyses 3,345 reviews of Go KL City Bus, Light Rail Transit (LRT) Kelana Jaya Line, Mass Rapid Transit (MRT), Monorail and RapidKL Bus in Kuala Lumpur, manually using NVivo 12.0 to determine their reasons for using the bus service through content analysis. The findings indicate that the majority of the tourists’ motivation to ride public transport is for sightseeing and exploring the city for free. Understanding tourists’ motivation to use public transport could assist tourism agencies in providing proper facilities for them to reach tourism destinations easily.
HEDONIC PRICING MODEL (HPM) ON SOUTH TANGERANG RESIDENTIAL PROPERTY VALUE
Authors: Darendra Noah Sidik , Riyanto Edy
Published: February 2025

This study investigates the effects of location, structural, and environmental attributes on residential property values in South Tangerang City, Indonesia.  The research employs the Hedonic Pricing Model (HPM), formulated mathematically using the multiple linear regression approach to determine the relative contribution given by these attributes. To achieve the objective, data were collected from information on residential properties in South Tangerang City which is accessible on various property buying and selling websites. The data collection was limited from July 2023 to January 2024. The results showed that some variables affected the value of residential properties, such as distances to KRL stations, public parks, top high schools, and the Central Business District (CBD), as well as building areas, land areas, and the number of rooms (bathrooms and bedrooms). However, other variables, such as distances to malls, hospitals, universities, and population density, had no partial effect on residential property values. If we look at the types of variables, the standardized coefficient beta test revealed that building areas were the most dominant variable affecting the property values in the region. This finding is different from other results, showing that property values are local. The influence of property attributes can vary across regions, so the impacts and relationships are different, too.
INVESTIGATING THE CORRELATION BETWEEN PROPERTY OVERHANG AND HOUSING SATISFACTION AMONG HOME BUYERS IN MALAYSIA
Authors: Kanniyapan Gunavathy , Fern Isabelle Marie Ting Yar , Mahdzir Mazura , Muniyandi Shantha Kumari , Vasudevan Gunalaan
Published: February 2025

The Malaysian real estate sector has flourished due to the rapid advancement of the global economy in recent years. Nevertheless, property overhang continues to threaten the nation’s economy. This study seeks to enhance developers’ comprehension of purchasers’ preferences by assessing the correlation between characteristics contributing to residential overhang along with variables affecting satisfaction levels with residential buildings. Questionnaire surveys were distributed to 157 developers and property agents, of which 110 were completed and returned. Similarly, 148 surveys were distributed to homebuyers, with 110 responses received. The data was evaluated using the Statistical Package for the Social Sciences (SPSS) version 24.0, where Bivariate Correlation Analysis was performed. The study’s results indicated a positive correlation between the majority of the parameters, while a few exhibited a negative correlation with one another. Future research may examine the effects of property overhang on the nation and provide strategies to mitigate these effects, therefore raising awareness among developers, the real estate sector, and the construction sector.
AN EVALUATION OF THE ROLE OF PHYSICAL LAYOUT IN CAMPUS MASTERPLAN DESIGN TO PROMOTE SUSTAINABILITY
Authors: Zarmani Siti Mazlina , Abdul Latip Nurul Syala , Ismail Noor Hayati
Published: February 2025

Many of the current campus design development tends to be more ad-hoc and focus more on free-standing buildings in the landscape settings that do not respond to the environment of the local contexts. Those designs have been criticized for creating a high dependency on automobiles, sprawling and segregating campus outdoor spaces with roads and large parking lots that pose challenges to meet sustainability goals. This paper aims to evaluate the role of physical layout in the design of campus masterplan at Malaysian Public Universities (MPUs) to promote sustainability. Using a qualitative method of a multiple case study, a connection between physical layout and sustainability was evaluated based on document reviews, morphological studies, visual surveys, and semi-structured interview techniques. The finding reveals that the physical layout plays an important role in promoting a sustainable campus environment. It is recommended to emphasize the design of physical layout in the MPUs’ campus masterplan to ensure compactness and structured configurations, which enhance design sustainability. These are important attributes in the design approaches that should be taken by MPUs for it to be agents of sustainability.
LIFE CYCLE COST (LCC) OF UNIVERSITY BUILDING MAINTENANCE: A SYSTEMATISED REVIEW
Authors: Ayob Mohd Fairullazi , Mohamed Yunus Mohd. Yusri , Hashim Khairusy Syakirin Has‐Yun , Sapian Abdul Razak , Haron Ahmad Tarmizi
Published: February 2025

An effective maintenance management is predominantly important for university building, but commentators advocated it is more important for the maintenance strategies to be designed based on the efficient use of capital and resources. Commentators pointed out there has been a critical demand to improve the traditional building maintenance policy that based on annual budget availability to prevent unforeseen restriction that can hinder a comprehensive implementation of building maintenance works. To overcome this, the life cycle cost (LCC) economic assessment technique has been recommended as an ideal solution that can facilitate the university agencies in the decision making to determine the most optimum building maintenance cost and financial capability over the anticipated study life. However, there is a need to identify any establishment link between the LCC with university building maintenance. Therefore, this paper is prepared with the objective to present the outcome of systematised review on life cycle cost (LCC) with specific reference to university building maintenance. A comprehensive review was conducted by searching databases, titles and abstracts screen, full-text analysis and data extraction on the targeted articles that have discussed the university building maintenance or indicated any form of building maintenance management elements with specific reference to LCC. The articles were identified from Google Scholar, Emerald, SAGE Scopus, My Cite, SpringerLink, as well as other databases. The findings indicate that many studies focused on building maintenance, however, there has been no specified guidelines concentrated on the LCC analysis of university building maintenance, which can be deliberated for practical guidance of maintenance management by the university agencies to attain value for money and making the university buildings and teaching and learning facilities economically wise use over the long term.
Clinical and Molecular Profile of Dystrophin Gene Deletions in Eastern Morocco
Authors: Fatimazahra Smaili , Khawla Zerrouki , Ezzahra Aouni Fatima , Ayad Ghanam , Maria Rkain , Abddeladim Babakhouya , Mariam Tajir
Published: February 2025

Dystrophinopathies are genetic muscular disorders with recessive inheritance linked to the X chromosome due to mutations in the dystrophin gene, the DMD gene located in Xp21. The best-known forms are Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Our study aims to determine the molecular profile and genotype/phenotype correlations of dystrophinopathies in the eastern region of Morocco. We report patients referred for 4 years (2020-2023) to the Medical Genetics Laboratory of the Mohammed VI University Hospital in Oujda for suspected dystrophinopathy and confirmed by a genetic study of the DMD gene using the PCR- Multiplex technique. A total of 15 patients were recruited. They had a mean age of 7.3 years at diagnosis, with a mean age of symptom onset of 3.37 years. Consanguinity was estimated at 46.66%, with 13.33% of familial forms. All patients have a DMD phenotype; calf hypertrophy was present in 86.66% of cases, a positive GOWERS sign, and elevated CK levels were present in all patients. Analysis of the DMD gene using the PCR-Multiplex technique showed that 80% of deletions are located in the central region of the gene, exon 50 being the most frequently deleted. 80% of patients had a deletion disrupting the reading frame, and the genotype/phenotype correlation in these cases was explained by the Monaco rule. The molecular analysis of the DMD gene is essential for accurate diagnosis, appropriate genetic counseling, and improved patient care. The PCR-Multiplex technique remains a good first-line strategy in the public health system, with a good cost/benefit ratio, enabling the detection of large deletions by analyzing the most frequently deleted exons. Dystrophinopathies represent a frequent reason for requesting genetic analysis in our practice. Multiplex PCR being a simple, rapid, non-invasive and cost-effective tool allowed us to provide a molecular description of this pathology in Eastern Morocco.
Measuring Post-Exertional Malaise with DePaul Symptom Questionnaires: Challenges and Opportunities
Authors: Jason Leonard A.
Published: February 2025

Following mental or physical exertion, patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience Post-Exertional Malaise (PEM). Although self-report questions represent less expensive and invasive procedures to assess PEM, variability in the wording of the symptom can cause reliability and validity problems. If different PEM measures are used in studies, this could create difficulties in replicating findings, identifying biomarkers, and determining effective treatments for patients. The objective of this article is to describe the challenges and opportunities of the PEM questions of the DePaul Symptom Questionnaires (DSQ) in specific. The five PEM DSQ items can identify 97% of patients with ME/CFS. A brief DSQ-PEM instrument has now been constructed that consists of five DSQ PEM items and five DSQ supplementary items such as symptom duration and how quickly patients would recover from activities. A more comprehensive instrument called the DePaul Post-Exertional Malaise Questionnaire assesses a more comprehensive list of PEM triggers and the duration and length of recovery time from PEM. In this article, we show how the DSQ’s PEM self-report items can provide clues to ME/CFS pathophysiology as well as how these items can be used as outcome measures. Future research should focus on contrasting and comparing different ways of eliciting PEM, assessing relationships between PEM self-report questionnaires and biomarkers, and examining the impact of treatment trials on PEM.
Metaverse Clinic for Pregnant Women With Subclinical Hypothyroidism: Prospective Randomized Study
Authors: Zheng Yuanyuan , Chen Yizhen , Chen Yan , Lin Liang , Xue Ting , Chen Chuhui , Wen Junping , Lin Wei , Chen Gang
Published: February 2025

Background

Health care is experiencing new opportunities in the emerging digital landscape. The metaverse, a shared virtual space, integrates technologies such as augmented reality, virtual reality, blockchain, and artificial intelligence. It allows users to interact with immersive digital worlds, connect with others, and explore unknowns. While the metaverse is gaining traction across various medical disciplines, its application in thyroid diseases remains unexplored. Subclinical hypothyroidism (SCH) is the most common thyroid disorder during pregnancy and is frequently associated with adverse pregnancy outcomes.

Objective

This study aims to evaluate the safety and effectiveness of a metaverse platform in managing SCH during pregnancy.

Methods

A randomized controlled trial was conducted at Fujian Provincial Hospital, China, from July 2022 to December 2023. A total of 60 pregnant women diagnosed with SCH were randomly assigned into two groups: the standard group (n=30) and the metaverse group (n=30). Both groups received levothyroxine sodium tablets. Additionally, participants in the metaverse group had access to the metaverse virtual medical consultations and metaverse-based medical games. The primary outcomes were adverse maternal and offspring outcomes, and the secondary outcomes included the neurobehavioral development of offspring and maternal psychological assessments.

Results

Of the 30 participants in each group, adverse maternal outcomes were observed in 43% (n=13) of the standard group and 37% (n=11) of the metaverse group (P=.60). The incidence of adverse offspring outcomes was 33% (n=10) in the standard group, compared to 7% (n=2) in the metaverse group (P=.01). The Gesell Development Scale did not show significant differences between the two groups. Notably, the metaverse group demonstrated significantly improved scores on the Self-Rating Depression Scale and the Self-Rating Anxiety Scale scores compared to the standard group (P<.001 and P=.001, respectively).

Conclusions

The use of metaverse technology significantly reduced the incidence of adverse offspring outcomes and positively impacted maternal mental health. Maternal adverse outcomes and offspring neurobehavioral development were comparable between the two groups.

Trial Registration

Chinese Clinical Trial Registry ChiCTR2300076803; https://www.chictr.org.cn/showproj.html?proj=205905