bluuebunny/crossref_metadata_2025 huggingface dataset:
Automated Identification of Valid Model Networks Using Model-Based Systems Engineering
Authors: Berges Julius Moritz , Spütz Kathrin , Jacobs Georg , Kowalski Julia , Zerwas Thilo , Berroth Jörg , Konrad Christian
Published: December 2022

To handle increasing complexity in product development, model-based systems engineering (MBSE) approaches are well suited, in which the technical system is represented in a system model. To efficiently test requirements, domain models are integrated into the system model. For each purpose (e.g., battery lifetime calculation), there are typically several models at several fidelity levels. Since the model signatures (i.e., necessary inputs for the models and their outputs) differ depending on the fidelity level, not all models can be used in any development phase. In addition, due to the different model signatures, not all models can be combined arbitrarily to model networks. Currently, valid model networks in system models must be determined in a time-consuming, manual process. Therefore, this paper presents an approach that automates this task via the implementation of an algorithm that analyzes a system model and the model signatures and automatically returns all valid model networks. When input parameters, models or their signatures change, the algorithm updates automatically, and the user receives the valid model network without any manual effort. The approach is demonstrated with the running example of battery system development.
Prediction and Visualisation of SICONV Project Profiles Using Machine Learning
Authors: de Oliveira Andrade Adriano , Marques Leonardo Garcia , Resende Osvaldo , Andrade de Oliveira Geraldo , Rodrigues da Silva Souza Leandro , Alves Pereira Adriano
Published: December 2022

Background: Inefficient use of public funds can have a negative impact on the lives of citizens. The development of machine learning-based technologies for data visualisation and prediction has opened the possibility of evaluating the accountability of publicly funded projects. Methods: This study describes the conception and evaluation of the architecture of a system that can be utilised for project profile definition and prediction. The system was used to analyse data from 20,942 System of Management of Agreements and Transfer Contracts (SICONV) projects in Brazil, which are government-funded projects. SICONV is a Brazilian Government initiative that records the entire life cycle of agreements, transfer contracts, and partnership terms, from proposal formalisation to final accountability. The projects were represented by seven variables, all of which were related to the timeline and budget of the project. Data statistics and clustering in a lower-dimensional space calculated using t-SNE were used to generate project profiles. Performance measures were used to test and compare several project-profile prediction models based on classifiers. Results: Data clustering was achieved, and ten project profiles were defined as a result. Among 25 prediction models, k-Nearest-Neighbor (kknn) was the one that yielded the highest accuracy (0.991±0.002). Conclusions: The system predicted SICONV project profiles accurately. This system can help auditors and citizens evaluate new and ongoing project profiles, identifying inappropriate public funding.
Combined Treatment of Parts Produced by Additive Manufacturing Methods for Improving the Surface Quality
Authors: Grigoriev Sergey , Metel Alexander , Volosova Marina , Melnik Yury , Mustafaev Enver
Published: December 2022

To improve the quality of a part manufactured by the additive method, it is necessary to eliminate the porosity and high roughness of its surface, as well as to deposit a coating on it. For this purpose, in the present work, we studied the combined processing in a gas discharge plasma of complex shape parts obtained by the additive manufacturing method, which includes explosive ablation of surface protrusions when voltage pulses are applied to the part immersed in the plasma; polishing with a concentrated beam of fast neutral argon atoms at a large angle of incidence on the surface of the part, and magnetron deposition of a coating on it with assistance by fast argon atoms. Combined processing made it possible to completely get rid of porosity and reduce the surface roughness from Ra ~ 5 µm to Ra ~ 0.05 µm.
Genetic Diversity of Microcystin Producers (Cyanobacteria) and Microcystin Congeners in Aquatic Resources across Africa: A Review Paper
Authors: Chia Mathias Ahii , Ameh Ilu , George Korie Chibuike , Balogun Emmanuel Oluwadare , Akinyemi Suwebat Ayanronke , Lorenzi Adriana Sturion
Published: December 2022

Microcystins are produced by multifaceted organisms called cyanobacteria, which are integral to Africa’s freshwater environments. The excessive proliferation of cyanobacteria caused by rising temperature and eutrophication leads to the production and release of copious amounts of microcystins, requiring critical management and control approaches to prevent the adverse environmental and public health problems associated with these bioactive metabolites. Despite hypotheses reported to explain the phylogeography and mechanisms responsible for cyanobacterial blooms in aquatic water bodies, many aspects are scarcely understood in Africa due to the paucity of investigations and lack of uniformity of experimental methods. Due to a lack of information and large-scale studies, cyanobacteria occurrence and genetic diversity are seldom reported in African aquatic ecosystems. This review covers the diversity and geographical distribution of potential microcystin-producing and non-microcystin-producing cyanobacterial taxa in Africa. Molecular analyses using housekeeping genes (e.g., 16S rRNA, ITS, rpoC1, etc.) revealed significant sequence divergence across several cyanobacterial strains from East, North, West, and South Africa, but the lack of uniformity in molecular markers employed made continent-wise phylogenetic comparisons impossible. Planktothrix agardhii, Microcystis aeruginosa, and Cylindrospermopsis raciborskii (presently known as Raphidiopsis raciborskii) were the most commonly reported genera. Potential microcystin (MCs)-producing cyanobacteria were detected using mcy genes, and several microcystin congeners were recorded. Studying cyanobacteria species from the African continent is urgent to effectively safeguard public and environmental health because more than 80% of the continent has no data on these important microorganisms and their bioactive secondary metabolites.
Lysine Inhibits Hemolytic Activity of Staphylococcus aureus and Its Application in Food Model Contaminated with Staphylococcus aureus
Authors: Wan Yangli , Wang Xiaowen , Bai Tianyi , Zheng Xuting , Yang Liu , Li Qianhong , Wang Xin
Published: December 2022

Alpha-hemolysin (Hla) is one of the important exotoxins of Staphylococcus aureus (S. aureus) and can be used as a target to reduce the virulence of S. aureus. This study explored the inhibitory effect of Lysine (Lys) on Hla and its application in food safety. Lys significantly inhibited the expression of Hla at sub-inhibitory concentrations and directly interacted with Hla to interfere with its oligomerization and thus significantly inhibited its hemolytic activity. Notably, Lys attenuated S. aureus damage to mouse small intestine and Caco-2 cells and delayed mouse mortality. In the food model, Lys inhibited the expression of Hla of S. aureus and had no significant effect on the sensory score. Moreover, Lys had no obvious damage effect on the main organs of mice, which indicated that Lys has good biocompatibility and has the potential to be used in the food industry as an anti-S. aureus preparation.
COVID-19 and Pasteurella multocida Pulmonary Coinfection: A Case Series
Authors: Cabras Ornella , Turmel Jean-Marie , Olive Claude , Bigeard Bastien , Lehoux Mélanie , Pierre-Francois Sandrine , Guitteaud Karine , Abel Sylvie , Cuzin Lise , Cabié André
Published: December 2022

Objectives: In COVID-19 patients, bacterial and fungal pulmonary coinfections, such as Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, or Aspergillus, have been reported, but to our knowledge, no case has been reported due to Pasteurella multocida. Patients and methods: We describe three cases of Pasteurella multocida coinfections occurring during the 4th wave of COVID-19 in Martinique (French West Indies). Results: All three cases were fatal; thus, Pasteurella multocida has to be considered as a potentially severe coinfection agent. Conclusions: Alteration of the epithelial–endothelial barrier due to a SARS-CoV-2 infection probably promotes the expression of a Pasteurella infection. In addition, the SARS-CoV-2 infection induced immunosuppression, and an inflammatory cascade could explain the infection’s severity. The use of corticosteroids, which are part of the first-line therapeutic arsenal against COVID-19, may also promote the pathogenicity of this agent.
Development and Visualization Improvement for the Rapid Detection of Decapod Iridescent Virus 1 (DIV1) in Penaeus vannamei Based on an Isothermal Recombinase Polymerase Amplification Assay
Authors: Xu Yajin , Wang Yan , Hu Jingjie , Bao Zhenmin , Wang Mengqiang
Published: December 2022

Viral diseases have seriously restricted the healthy development of aquaculture, and decapod iridescent virus 1 (DIV1) has led to heavy losses in the global shrimp aquaculture industry. Due to the lack of effective treatment, early detection and regular monitoring are the most effective ways to avoid infection with DIV1. In this study, a novel real-time quantitative recombinase polymerase amplification (qRPA) assay and its instrument-free visualization improvement were described for the rapid detection of DIV1. Optimum primer pairs, suitable reaction temperatures, and probe concentrations of a DIV1-qRPA assay were screened to determine optimal reaction conditions. Then, its ability to detect DIV1 was evaluated and compared with real-time quantitative polymerase chain reactions (qPCRs). The sensitivity tests demonstrated that the limit of detection (LOD) of the DIV1-qRPA assay was 1.0 copies μL−1. Additionally, the presentation of the detection results was improved with SYBR Green I, and the LOD of the DIV1-RPA-SYBR Green I assay was 1.0 × 103 copies μL−1. Both the DIV1-qRPA and DIV1-RPA-SYBR Green I assays could be performed at 42 °C within 20 min and without cross-reactivity with the following: white spot syndrome virus (WSSV), Vibrio parahaemolyticus associated with acute hepatopancreatic necrosis disease (VpAHPND), Enterocytozoon hepatopenaei (EHP), and infectious hypodermal and hematopoietic necrosis virus (IHHNV). In conclusion, this approach yields rapid, straightforward, and simple DIV1 diagnoses, making it potentially valuable as a reliable tool for the detection and prevention of DIV1, especially where there is a paucity of laboratory equipment.
Consequences of In Utero Zika Virus Exposure and Adverse Pregnancy and Early Childhood Outcomes: A Prospective Cohort Study
Authors: Grant Rebecca , Flechelles Olivier , Elenga Narcisse , Tressières Benoît , Gaete Stanie , Hebert Jean-Christophe , Schaub Bruno , Djossou Felix , Mallard Adeline , Delver Lucetta , Ryan Catherine , Funk Anna L. , Cabié André , Fontanet Arnaud , Hoen Bruno
Published: December 2022

We aimed to describe adverse pregnancy outcomes among women who had symptomatic, RT-PCR-confirmed ZIKV infection and early childhood outcomes among their infants. We enrolled pregnant women with symptomatic, RT-PCR-confirmed ZIKV infection in a prospective cohort study, and their infants in a prospective pediatric cohort study. We defined adverse pregnancy and early childhood outcomes based on selected neurologic, ophthalmologic, auditory, musculoskeletal, and anthropometric abnormalities. We used RT-PCR and serologic tests to determine the ZIKV infection status of the child. Between 10 March and 24 November 2016, we enrolled 546 pregnant women with RT-PCR-confirmed ZIKV infection. The overall risk of adverse pregnancy and early childhood outcomes possibly related to in utero ZIKV exposure was 15.7% (95% CI: 12.8–19.0), distributed as follows: 3.6% (95% CI: 2.3–5.6) severe sequelae or fatality; 2.7% (95% CI: 1.6–4.5) major abnormalities; 9.4% (95% CI:7.1–12.2) mild abnormalities. The risk of severe sequelae or fatality was higher when ZIKV infection occurred during the first trimester (7.0%), compared to the second (2.7%) or third trimester (1.4%) (p = 0.02). Among the infants for whom ZIKV infection status could be determined, the vertical transmission rate was 3.0% (5/167) (95% CI: 1.1–7.2). Among pregnant women with symptomatic, RT-PCR-confirmed ZIKV infection, severe or major pregnancy or early childhood outcomes were present in 6.3% of fetuses and infants. Severe outcomes occurred more frequently in fetuses and infants whose mothers had been infected in the first trimester.
Risk of Viral Infectious Diseases from Live Bats, Primates, Rodents and Carnivores for Sale in Indonesian Wildlife Markets
Authors: Morcatty Thais Q. , Pereyra Paula E. R. , Ardiansyah Ahmad , Imron Muhammad Ali , Hedger Katherine , Campera Marco , Nekaris K. Anne-Isola , Nijman Vincent
Published: December 2022

Southeast Asia is considered a global hotspot of emerging zoonotic diseases. There, wildlife is commonly traded under poor sanitary conditions in open markets; these markets have been considered ‘the perfect storm’ for zoonotic disease transmission. We assessed the potential of wildlife trade in spreading viral diseases by quantifying the number of wild animals of four mammalian orders (Rodentia, Chiroptera, Carnivora and Primates) on sale in 14 Indonesian wildlife markets and identifying zoonotic viruses potentially hosted by these animals. We constructed a network analysis to visualize the animals that are traded alongside each other that may carry similar viruses. We recorded 6725 wild animals of at least 15 species on sale. Cities and markets with larger human population and number of stalls, respectively, offered more individuals for sale. Eight out of 15 animal taxa recorded are hosts of 17 zoonotic virus species, nine of which can infect more than one species as a host. The network analysis showed that long-tailed macaque has the greatest potential for spreading viral diseases, since it is simultaneously the most traded species, sold in 13/14 markets, and a potential host for nine viruses. It is traded alongside pig-tailed macaques in three markets, with which it shares six viruses in common (Cowpox, Dengue, Hepatitis E, Herpes B, Simian foamy, and Simian retrovirus type D). Short-nosed fruit bats and large flying foxes are potential hosts of Nipah virus and are also sold in large quantities in 10/14 markets. This study highlights the need for better surveillance and sanitary conditions to avoid the negative health impacts of unregulated wildlife markets.
Culex Mosquito Piwi4 Is Antiviral against Two Negative-Sense RNA Viruses
Authors: Walsh Elizabeth , Torres Tran Zen B. , Rückert Claudia
Published: December 2022

Culex spp. mosquitoes transmit several pathogens concerning public health, including West Nile virus and Saint Louis encephalitis virus. Understanding the antiviral immune system of Culex spp. mosquitoes is important for reducing the transmission of these viruses. Mosquitoes rely on RNA interference (RNAi) to control viral replication. While the siRNA pathway in mosquitoes is heavily studied, less is known about the piRNA pathway. The piRNA pathway in mosquitoes has recently been connected to mosquito antiviral immunity. In Aedes aegypti, Piwi4 has been implicated in antiviral responses. The antiviral role of the piRNA pathway in Culex spp. mosquitoes is understudied compared to Ae. aegypti. Here, we aimed to identify the role of PIWI genes and piRNAs in Culex quinquefasciatus and Culex tarsalis cells during virus infection. We examined the effect of PIWI gene silencing on virus replication of two arboviruses and three insect-specific viruses in Cx. quinquefasciatus derived cells (Hsu) and Cx. tarsalis derived (CT) cells. We show that Piwi4 is antiviral against the La Crosse orthobunyavirus (LACV) in Hsu and CT cells, and the insect-specific rhabdovirus Merida virus (MERDV) in Hsu cells. None of the silenced PIWI genes impacted replication of the two flaviviruses Usutu virus (USUV) and Calbertado virus, or the phasivirus Phasi-Charoen-like virus. We further used small RNA sequencing to determine that LACV-derived piRNAs, but not USUV-derived piRNAs were generated in Hsu cells and that PIWI gene silencing resulted in a small reduction in vpiRNAs. Finally, we determined that LACV-derived DNA was produced in Hsu cells during infection, but whether this viral DNA is required for vpiRNA production remains unclear. Overall, we expanded our knowledge on the piRNA pathway and how it relates to the antiviral response in Culex spp mosquitoes.
Fighting Death for Living: Recent Advances in Molecular and Genetic Mechanisms Underlying Maize Lethal Necrosis Disease Resistance
Authors: Johnmark Onyino , Indieka Stephen , Liu Gaoqiong , Gowda Manje , Suresh L. M. , Zhang Wenli , Gao Xiquan
Published: December 2022

Maize Lethal Necrosis (MLN) disease, caused by a synergistic co-infection of maize chlorotic mottle virus (MCMV) and any member of the Potyviridae family, was first reported in EasternAfrica (EA) a decade ago. It is one of the most devastating threats to maize production in these regions since it can lead up to 100% crop loss. Conventional counter-measures have yielded some success; however, they are becoming less effective in controlling MLN. In EA, the focus has been on the screening and identification of resistant germplasm, dissecting genetic and the molecular basis of the disease resistance, as well as employing modern breeding technologies to develop novel varieties with improved resistance. CIMMYT and scientists from NARS partner organizations have made tremendous progresses in the screening and identification of the MLN-resistant germplasm. Quantitative trait loci mapping and genome-wide association studies using diverse, yet large, populations and lines were conducted. These remarkable efforts have yielded notable outcomes, such as the successful identification of elite resistant donor lines KS23-5 and KS23-6 and their use in breeding, as well as the identification of multiple MLN-tolerance promising loci clustering on Chr 3 and Chr 6. Furthermore, with marker-assisted selection and genomic selection, the above-identified germplasms and loci have been incorporated into elite maize lines in a maize breeding program, thus generating novel varieties with improved MLN resistance levels. However, the underlying molecular mechanisms for MLN resistance require further elucidation. Due to third generation sequencing technologies as well functional genomics tools such as genome-editing and DH technology, it is expected that the breeding time for MLN resistance in farmer-preferred maize varieties in EA will be efficient and shortened.
The Origin of Capsid-Derived Immune Complexes and Their Impact on HBV-Induced Liver Diseases
Authors: Zhang Xiaonan , Tang Yijie , Wu Min , Wang Cong , Hu Lyuyin , Zhang Zhanqing
Published: December 2022

Over 240 million people worldwide are chronically infected with Hepatitis B Virus (HBV), a hepatotropic DNA virus with an evolutionary root of over 400 million years. Persistent HBV infection exhibits distinct and diverse phases of disease, from minimal liver pathology to fulminant Hepatitis, that vary in duration and severity among individuals. Although huge progress has been made in HBV research which has yielded an effective prophylactic vaccine and potent antiviral therapy, our understanding of its virology and immunobiology is still far from complete. For example, the recent re-discovery of serum HBV RNA in chronic Hepatitis B (CHB) patients has led to the proposal of noncanonical viral particles such as RNA virion and capsid-derived immune complex (Capsid-Antibody-Complexes, CACs) that contradict long-established basic theory. Furthermore, the existence of capsid-derived immune complex may hint at novel mechanism of HBV-induced liver disease. Here, we summarize the past and recent literature on HBV-induced immune complex. We propose that the release of capsid-derived particles by HBV has its deep evolutionary origin, and the associated complement activation serves as an indispensable trigger for intrahepatic damage and a catalyst for further cell-mediated immunopathology.
Immune Profile of Blood, Tissue and Peritoneal Fluid: A Comparative Study in High Grade Serous Epithelial Ovarian Cancer Patients at Interval Debulking Surgery
Authors: Kumar Pavan , Ranmale Samruddhi , Tongaonkar Hemant , Mania-Pramanik Jayanti
Published: December 2022

High-grade serous epithelial ovarian carcinoma (HGSOC) is an immunogenic tumor with a unique tumor microenvironment (TME) that extends to the peritoneal cavity. The immunosuppressive nature of TME imposes the major challenge to develop effective treatment options for HGSOC. Interaction of immune cells in TME is an important factor. Hence, a better understanding of immune profile of TME may be required for exploring alternative treatment options. Immune profiling of peritoneal fluid (PF), tumor specimens, and blood were carried out using flowcytometry, ELISA, and Procartaplex immunoassay. The frequency of CD56BrightNK cells and expression of functional receptors were reduced in PF. Increased activating NKp46+CD56DimNK cells may indicate differential antitumor response in PF. Functional receptors on NK, NKT-like and T cells were reduced more drastically in tumor specimens. Soluble ligands MIC-B and PVR were reduced, whereas B7-H6 was increased in PF. Dissemination of tumor cells contributes to soluble ligands in PF. A differential cytokine profile was found in serum and PF as IL-2, IL-8, IL-15, IL-27, IFN-γ, and GM-CSF were elevated specifically in PF. In conclusion, the differential immune profile and correlation of soluble parameters and NK cell receptors with chemo response score may add knowledge to understand anti-tumor immune response to develop effective treatment modality.
THE INTERNALLY MIGRANT STUDENTS’ ADAPTATION TO THE ENVIRONMENT OF UNIVERSITY BY MEANS OF TRAINING ACTIVITIES
Authors: BELYAEVA N. , BOLOVATSKA Y.
Published: December 2022

The article deals with the problem of the internally migrant students’ adaptation to the environment of university by means of training activities. The various aspects of support for internally displaced youth have been analyzes in the article. The most effective forms, methods and means of educational activity in higher educational institutions are considered. The authors underlines in the article that the Students involved in educational activities feel comfortable in the  new student community and realizing themselves in their own projects and programs.Involvement of internally displaced persons in the arsenal of various forms of educational activities helps to overcome the obstacles encountered by settlers. In the course of the research and the questionnaire survey, we identified two key groups of such difficulties, in particular: the educational and organizational difficulties that arise when organizing the educational process in higher education and organizing the life of a student outside the university; psychological difficulties that manifest themselves in increasing  the rate of emotional excitement,  anxiety,  neuroticism; reducing  communicability, emotional stability, self-control, etc.An effective means of adapting internally displaced persons to the university's educational environment is educational activity that allows  the settler to feel  fit in  the new student community, make a personal  contribution to solving social problems and overcome the difficulties associated with forced migration processes in Ukraine.
THE ROLE OF RATIONA-THEORETICAL AND EMOTIONAL APPROACH
Authors: GRYTSENKO L.
Published: December 2022

The article deals with the specifics of the implementation of the unity of human pedagogy in Makarenko education goals as a whole person and of creating an integrated educational system through the use of two complementary ways: rational-scientific and emotionally-shaped building on a third way - the practice-activity. This integrative approach is associated with the personal qualities of an outstanding teacher that is in line with professiogenesis, ie the formation of a professional in the area of its qualities and events in his life.The author claims that the personality of A.S. Makarenko, representing the unity of exceptional research abilities, the artistry of his nature and the act activity principle, was the most important factor that determined the methodology for building the Makarenko`s pedagogical system. At the same time, the comprehension of pedagogical reality was realized by A.S. Makarenko rational scientific, emotional-figurative and empirical ways. In many respects it is this a holistic, voluminous approach, in which the merits of each method are accumulated, allowed the innovator pedagogue to create a unique pedagogical system that is a contribution not only to domestic but to world pedagogy.
THE PROBLEMS OF HIGHER AGRARIAN EDUCATION IN THE POST-SOVIET STATES
Authors: KARYCHKOVSKYI V.
Published: December 2022

The job market is changing at a more rapid speed than ever, influenced by developing industries and business models. Today's job markets and in-demand skills will look significantly different. The importance of implanting employability as a serious value and attitude throughout the higher education segment has never been stronger. Graduate employability means that higher education alumni developed the capacity to get work. Moreover, employability means that institutions and employers have supported the student knowledge, skills, qualities, philosophical outlook and individuality that graduates need to be successful in the labor force. In the article, on the basis of the review of scientific and educational literature, a theoretical analysis of the processes of vocational guidance and employment of graduates of agricultural universities in the Russian Federation was carried out. In particular, the problem of the discrepancy between theoretical knowledge and practical skills was noted, one of the main problems of agriculture - the lack of qualified specialists was identified, the main directions of agro-professional orientation processes were revealed on the basis of the synergetic approach, considerable attention was focused on the employment of graduates and cooperation of employers with higher educational institutions both on issues of employment, and traineeships. Successful implementation of the agrarian universities of its public mission was and is a necessary, but not sufficient condition for satisfying the personnel needs of the agribusiness. The optimality of the proportions of providing specific organizations and regions with skilled personnel, motivation of work, professional development of workers, their career growth and much more determines the efficiency of the use of human resources.In the modern world, the ability to retrain and mobility has already been recognized as the most important qualities of professionals of any age, and this circumstance should be taken into account when developing the criteria for the employment of graduates.
MASTERING THE EXPERIENCE OF CREATIVE ACTIVITY BY SPECIALTY OF FUTURE DOCTORS IN THE PROCESS OF NATURAL-SCIENCE TRAINING
Authors: MAKARENKO V.
Published: December 2022

The author analyzes the possibilities of mastering the experience of creative activity on the specialty of future doctors in the process of natural science training; it was revealed that professional competence of the doctor is formed and perfected with mastering of experience of creative activity in the specialty; with the aim of mastering and enriching the experience of creative activity on the specialty to use the complex of pedagogical conditions in the process of natural science training (development of the professional environment; actualization of the professional potential of science and education; the direction of educational, cognitive and scientific activity of the students for the formation of professional competencies) is proposed; examples of the implementation of this approach are provided by means of vocational guidance in the process of science education, in particular, the use of a rationally-selected system of professionally- oriented tasks for classroom and non-audiences of students; the results of experimental research conducted in medical universities are presented; it was indicated that the introduction of the mentioned pedagogical conditions into the process of natural science training provided statistically significant positive changes in the indicators of the formation of the experience of creative activity in the specialty; prospects for further exploration are outlined.
EDUCATION OF PERSONALITY OF FUTURE TEACHER BY MEANS OF OLYMPISM
Authors: MOMOT O.
Published: December 2022

In the article education of personality of future teacher is described by means of olympism as vital philosophy, that glorifies and unites in harmonious unit the internalss of body, will and mind. Combining sport with a culture and education, olympism aims to create such way of life, that would be based on the gladnesses obtained through effort, educational values of kind example and respect of universal ethic principles.The plan of work of the Poltava regional branch of the Olympic academy of Ukraine is shown. A separation is the guide- book of distribution of olympic, healthy ideas. One of directions of activity of that there is education of personality of future teacher by facilities of olympism, health and creation of healthy environment of high school. It would give an opportunity to deepen knowledge of personality of future teacher about Olympic ideas, Olympic movement, Olympic games of remoteness and contemporaneity, about importance of development of spiritual and physically developed personality. Such approach would give  an opportunity to warn such dangerous negative  phenomena, as smoking, alcoholism, drug addiction and to inoculate to the future specialists love to the environment and health. Except it to interest young people in athletic-sporting activity that is a substantial push in creation of  healthy environment  of  high school.
DEVELOPMENT OF VALELOLOGICAL EDUCATION IN EDUCATIONAL INSTITUTIONS OF THE SOUTH OF UKRAINE (END OF THE 19TH - 1917)
Authors: PIENOV V.
Published: December 2022

In the article the historical and pedagogical analysis of the problem of the development of valeological education in educational institutions in the southern Ukrainian lands (at the end of the nineteenth century – 1917) has been performed; the characteristic features of the development of valeological education in the women's and men's gymnasia, real schools, private and public gymnasia in the south of Ukraine and the empire on a whole, in which a significant place was devoted to valeological education of pupils and the teaching of subjects of valeological cycle, have been defined.The development of valeological education in Ukraine in the late 19th and early 20th centuries corresponded the general imperial policy. However, the specifics of the regions determined its peculiarities on the local level. The goals of the educational process and the educational tasks that the school faced had different ways of implementation and their regional tints. In the south of Ukraine in the 19th century, cities such as Kherson, Mykolaiv, and Odessa became centers of secondary education.The 80s of the 19th century became the starting point of education system reformation in the Russian Empire. Trends existing in society also reflected in the development of the education of the South of Ukraine, but considering certain diversity of this region, peculiar conditions for reforming education, especially its middle level, arose. One of the directions that was supposed to be distinguished and given more weight was a health improvement direction in the upbringing of schoolchildren.Valeological education in this period was guided by the principles of democratic pedagogy. Its main goals were to familiarize students with valeological values. The implementation of these goals was based on the subjects of the valeological cycle.The author concludes that the teaching of the subjects of the valeological cycle in the women’s gymnasia was at a higher level than that of the men’s. It was due to the orientation of education, which included preparing men for state service, and women – for the role of mother. A prominent place in the system of valeological education was taken by educational institutions of the medical branch.
A Comparative View between Valayanad Devi and Chamundi Deities
Authors: R Rejitha
Published: December 2022

Literature helps us to know about a country, people, beliefs, professions and races but it doesn’t give a clear idea about folklore. Folklore literature is a storehouse of what human society has experienced and learned. At beginning man lived his life according to his wish. The only source for him is nature and they worshipped nature. From that many festivals, beliefs and sacrifices are formed. They separated worshipping as minor deity worship and major deity worship. Folk literature is created and preserved by the lay people. The history of the deities is told in mythological stories and epics. Each deity has its own myths. The aim of this article is to compare the beliefs, rituals and ceremonies between the Valayanad Devi and Samundi Deities.
Song of Proverbs by Thirumangai Aalwar
Authors: N Shubha
Published: December 2022

Proverbs are used as gateways to express the thoughts, living conditions and beliefs of the society. Proverbs also express the cultural elements. In that way in Vaishnava religious songs, especially in the hymns, Alwars have used proverbs to preach, moralize and rebuke indirectly. Thirumangai Alwar has used many proverbs. In particular, it is known that proverbs are used in the places where the mother sympathizes with the Lord (Kannan) in an attempt to connect the heroine (Parakala Nayaki). In particular they have been divided into the categories of biological elements, metaphorical welfare, emotional and religious philosophical elements. As it fully composed of proverbs it is called “Song of Proverbs”.
Life Values in the Proverbs used in Vilavangodu Region
Authors: S. L Helen Japa Rose
Published: December 2022

Proverbs is one of the literary forms.  Like folk songs, folk tales, fairy tales etc., proverbs belong to the genre of oral literature. A proverb is a language that originates from primitive knowledge. Describing an object in one or two lines without directly describing it is called riddles. In Tamil it is called pisi or nodi. These riddles help in developing intellectual activities. Mothers use riddles to develop their child's intellectual power. Proverbs have appeared in all the languages and it is intertwined with people's lives. Proverbs have been used by the Tamil people since the ancient time itself. Proverbs is the shortest form of oral language-based folk idioms.  It has a great impact on people. Even today riddles are most commonly used by all humans. Our forefathers have used to say proverbs to indicate certain actions in the rural areas, to make comments and create awareness.  It is infused with experience and knowledge.  It can be said that it is the experience of a society's long-term circulation. In particular, proverbs describe something succinctly, clearly and beautifully. This article is in a position to establish how these proverbs are learned and used by the people Vilavankodu region.
A Study of Karakaatakalai
Authors: S Vignesh
Published: December 2022

Humans after finishing their food they spend their time usefully. Thus, they found out many arts and enjoyed it. They not only created art they himself enrolled in it and make others happy. Folk arts have developed with the only intention to make others happy. Then it can be divided into three types. They are folk practices, folk arts and folk science. Karakkatam is one of the very famous art in Tamil Nadu. This article says about karakattam art, its types and its importance with the help of two novels.
Analisis Efisiensi Agroindustri Tauge (Vigra Radiata) (Studi Kasus Di Agroindustri Tauge Di Desa Cileles Kecamatan Jatinangor Kabupaten Sumedang)
Authors: Prana Hikmat , Nataliningsih Nataliningsih , Permana Nendah Siti
Published: December 2022

This study aims to determine the amount of cost, revenue, and income as well as the level of efficiency in the Tauge Agroindustry business in Cileles Village, Jatinangor District, Sumedang Regency. In this research, a case study method was carried out through a quantitative descriptive approach. The results of this study indicate that the total cost incurred is Rp 10.985.235, - per production, total revenue of Rp 16.011.300, - per production, and revenue on total costs of Rp 5.026.065, - per production, as well as the level of business efficiency or the R / C ratio for variable costs of 1,46 or each cost of Rp 1 will result in a receipt of Rp 1.46 so it can be concluded that the bean sprouts agro-industry in Cileles Village, Jatinangor is profitable and efficient.
Peranan Faktor Sosial Ekonomi Dan Partisipasi Wanita Tani Dalam Kegiatan Kelompok Wanita Tani (KWT) Terhadap Keberhasilan Program Kawasan Rumah Pangan Lestari (KRPL) (Suatu Kasus pada Kelompok Wanita Tani (KWT) di Kecamatan Cianjur Kabupaten Cianjur)
Authors: Permana Rosdianti , Sukmawati Dety , Dasipah Euis
Published: December 2022

Tujuan penelitian ini adalah untuk mengetahui: (1) seberapa besar pengaruh faktor sosial ekonomi terhadap keberhasilan program KRPL; (2) seberapa besar pengaruh partisipasi anggota kelompok wanita tani terhadap keberhasilan program KRPL; (3) seberapa besar pengaruh faktor sosial ekonomi dan partisipasi anggota kelompok wanita tani terhadap keberhasilan program KRPL. Penelitian ini menggunakan metode survei dengan unit analisisnya adalah petani anggota kelompok wanita tani yang melaksanakan program Kawasan Rumah Pangan Lestari di Kecamatan Cianjur Kabupaten Cianjur. Teknik pengambilan sampel dilakukan secara sampling sebanyak 79 responden. Â Data yang terkumpul dianalisis dengan menggunakan analisis jalur (path analysis), analitik disesuaikan dengan hasil pengujian hipotesis. Hasil penelitian menunjukkan bahwa Faktor Sosial Ekonomi dan Partisipasi Anggota Kelompok Wanita Tani secara simultan berpengaruh signifikan terhadap Keberhasilan program KRPL sebesar 90,3 %. Sisanya sebesar 9,7 % dipengaruhi oleh faktor lain yang tidak diteliti dalam penelitian ini.
Analisis Usaha dan Faktor-Faktor Produksi Yang Mempengaruhi Usahatani Wortel (Daucus carota L) di Kabupaten Sukabumi (Suatu Kasus di Kelompok Tani Kecamatan Sukabumi Kabupaten Sukabumi)
Authors: Nurhanifah Siti , Dasipah Euis , Nataliningsih Nataliningsih , Sukmawati Dety , Permana Nendah Siti , Sondari Nunung
Published: December 2022

The aims and objectives of this research activity are to analyze the level of income and feasibility of carrot farming (Daucus carota L) and to find out what production factors have an influence on carrot farming in the tani group Kecamatan Sukabumi Regency Sukabumi The population to be studied is carrot farmers, a sample of 84. The Cobbs-Douglas production function is used to analyze the above The analysis showed independent variables: the amount of land area and the amount of fertilizer showed a significant effect on carrot farming, while the amount of medicine, the number of workers and the number of seeds showed no effect on farming of carrot. The financial gain from carrot farming per farmer is 25.151.236,31 IDR. per farmer or 41.087.200.51 IDR per hectare. The result of the analysis for the R/C Ratio is 2,76, indicating the R/C Ratio is > 1, which means farming carrots in areas research can be cultivated
Faktor-Faktor Yang Mempengaruhi Pendapatan Usahatani Sawo Sukatali ST.I (Achras Zapota L.) (Suatu Kasus di Desa Sukatali Kecamatan Situraja KabupatenSumedang)
Authors: Saepuloh Aef , KS Karyana , KS Karyana , Yohana Ana , Yohana Ana
Published: December 2022

The purpose of this study is to find out the factors that affect the income of sawo sukatali ST. I (Achras Zapota L.) In The Village.Sukatali District Situraja Sumedang Regency and to find out the level of productivity of farmers Sawo Sukatali ST. I (Achras Zapota L.) in Sukatali Village of Situraja District of Sumedang Regency. The analysis unit is farmers who do sawo Sukatali ST farming. I in one growing season. The research methods used in this research are descriptive and verifiative research with quantitative approaches. Based on the discussion and results of the analysis of this research data can be put forward the following conclusions : 1) The establishment of sawo farming business located in Sukatali Village of Situraja District of Sumedang Regency, namely a) subsystem of provision of production facilities and infrastructure (Hulu). b) Subsystem of Business (Cultivation of mustard plants). c) marketing subsystem (Downstream).2) Partially there are 3 variables (land area, productivity, price) that have a positive and significant effect on farmers' income. Simultaneously land area, productivity, production costs, prices, and marketing simultaneously or together have a significant effect on the income of sawo farmers located in Sukatali Villageof Situraja District of Sumedang Regency.3) The income of sawo farmers located in Sukatali Village of Situraja District of Sumedang Regency is fairly low. The average income of mustard farmers amounted to Rp. 5,916,235 per season.
Adollescent Characteristics Relation with Premarital Sex Attitudes
Authors: Febriani Irene , Kadiser Miden Destinady
Published: December 2022

Adolescence is an important part of individual development and begins with the maturity of the physical organs. Adolescents have the opportunity to obtain optimal health status, but adolescent behavior does not always support it. This study aims to analyze the relationship between age, education, gender and welfare with adolescent attitudes about premarital sex and risky behavior. Using secondary data from the 2019 Program Performance and Accountability Survey (SKAP) totaling 316 adolescents by systematic random sampling research design cross-sectional, carried out in 2020 with frequency distribution and chi square test. The results showed that 64.4% did not agree with premarital sex and did not engage in risky behavior. 91.2% of age related to premarital sex (P Value 0.005) and risky behavior (P Value 0.020). Gender is associated with premarital sex attitudes and risky behavior (P value 0.005). Family welfare variables are not related to premarital sex attitudes and risky behavior (P Value > 0.05). The content of information sources still needs to be considered, facilitators who disseminate information sources again need to be given training and the goals for providing information are adjusted and targeted.
THE STRUGGLE OF THE SOVIET POWER WITH THE VOLYN INSURGENT ARMY
Authors: Makarchuk I.
Published: December 2022

The purpose of the article is to analyze the formation of underground cells of the anti-Bolshevik insurgent movement in Volyn after the Second Winter Campaign of the UNR army. Coverage of the measures of the Soviet authorities, aimed at the detection, intelligence development and destruction of an underground organization of an insurgent character called the Volyn Insurgent Army, which operated on the territory of the Volyn Province during 1922.

Methodology. When writing the article, the basic principles of historical knowledge were used: historicism, scientificity, objectivity. Specific search tasks of the research were solved by problem-chronological means (optimal involvement of the thematic literature and source base); historical-comparative (analysis of various sources and formation of relevant research provisions and conclusions); critical analysis (critical attitude to various sources) methods.

The scientific novelty consists in a comprehensive study of the stages of detection and liquidation by Soviet law enforcement agencies of the Volyn rebel army on the basis of unpublished sources and the available historiographical base. New source material, in particular archival documents, important for solving the problem, was introduced into scientific circulation and analyzed.

Conclusions. The unsuccessful completion of the Second Winter Campaign of the UNR army accelerated the decline of the anti-Bolshevik insurgent movement, which continued under the repressive policy of the Soviet government. Even in such difficult conditions for the local insurgents, several underground cells began to operate on the territory of Volyn, which later merged into a whole insurgent organization called the Volyn Insurgent Army. The insurgents' activation and lack of conspiracy experience on their part allowed the Soviet authorities to discover that not just ordinary partisan units, but a whole underground organization with its own structure and tasks, began to operate in Volyn. In order to eliminate all the cells and structures of the VPA as effectively as possible, the Bolsheviks decided to infiltrate the rebels with their agents under the guise of members of the anti-Soviet underground. They successfully managed to do this and the work to identify all the participants of the underground continued. The success of the insurgents in expanding their network and their preparation for the uprising forced representatives of the Soviet authorities to quickly draw up a plan to eliminate the VPA. The very liquidation of the organization was quite successful for the Bolsheviks, because most of the members of the VPA were arrested or destroyed, although the underground command staff managed to retreat abroad.
LOCAL POLICE AND THE HOLOCAUST IN THE GENERAL DISTRICT “DNIPROPETROVSK” (EVIDENCE FROM THE DISTRICTS OF KRYVYI RIH AND STALINDORF)
Authors: Shliakhtych Roman , Mykhalchuk Roman
Published: December 2022

The purpose of the research is to study the involvement of local policemen in the Holocaust in the territory of the Dnipropetrovsk general district, in particular, the Kryvorizka and Stalindorf districts. The research methodology is based on general scientific, special historical research methods. The scientific novelty of the work lies in the fact that, on the basis of a wide source base, the memories of eyewitnesses, it was possible to establish the degree of involvement of the local police in the Holocaust, as well as to determine in which stages of the Holocaust representatives of the local police participated. The findings of the study indicate that most of the people involved in the Holocaust held commanding positions in the local police. Ordinary policemen were mainly engaged in gathering, guarding and escorting Jews to the places of execution, and sometimes personally killed them. Most of them came from rural areas and had little education.