bluuebunny/crossref_metadata_2025 huggingface dataset:
The GC MS Analysis of one Ayurvedic Medicine “Balarishtam”
Authors: D Sharmila , Rebecca L. Jeyanthi , Rao Mudiganti Ram Krishna
Published: August 2021

Balarishtam is an Ayurvedic nerve tonic. The present study deals with the GC MS analysis of the medicine to understand the biomolecules present and their possible nerve related activity. Balarishtam was subjected to GC MS analysis. The presence of some important molecules such as Eucalyptol, 2-Isopropoxyethylamine, p-menth-1-en-8-ol, Eugenol, N-Acetyl-. alpha.-methyl-4-ethynyl-2-thiazolemethanamine etc. has given a clue towards the nerve tonic effect of Balarishtam. Thus this study could lead to the identification of marker biomolecules which could help in validation of this drug as a nerve tonic.
Isolation, Characterization and Application of Protease Enzyme from Marine Bacteria
Authors: S Sneha , Palsokar Mrunal , Sai Jahnavi Vemula , Sarkar Anwesha , Rao K. V. Bhaskara
Published: August 2021

Protease constitutes the major group of catalytic enzymes which is involved in hydrolyzing peptide bond of proteins. Marine sediment sample were collected and protease producing bacterial isolates were identified by using casein as a substrate. The organisms were characterized by biochemical test and identified as Bacillus sp. In order to check for the production of protease enzyme, quantitative protease assay and Lowry’s method of protein estimation was carried out. The crude extract of protease was subjected for blood stain removal activity and the enzyme proved to be efficient which removed the stain in 15 min. The purpose of the current study is to isolate, identify, characterize and to carry out applications of protease enzyme from marine bacteria isolated from mangrove sediment samples.
Evaluation of Relaxant effect in Methanolic Extract of Aegle marmelos on Isolated Sprague Dawley Bronchial Tissue
Authors: R Surekha. , Kishore R. Ishwarya , Srinivasamoorthy Harini , Kumar V. Kishore , J. Athippathi
Published: August 2021

Introduction: Chronic obstructive pulmonary disease (COPD) is a common disease characterized by persistent airflow obstruction with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Oxygen deficiency (hypoxia) causes an increase in Reactive Oxygen Species (ROS). ROS can be neutralized with antioxidants, one of which is Bael leaf. Objective: To evaluate the antibacterial activity of plant leaf extract against the common isolated bacteria [Psuedomonas aeruginosa]. To know the Relaxant effect of bael leaf (Aegle marmelos) on oxidative stress in Sprague Dawley lung induced chronic systemic hypoxia. Methods: The study was conducted in SIMATS and Sri Akilandeswari Pharma College for the period of Six months from April 2020 to September 2020. 110 sputum samples were analysed for testing antibacterial activity. Neutralization of ROS has been determined by DPPH radical scavenging method. Contractile effect was done by the Organ bath method. Results: Among gram negative bacteria predominantly Pseudomonas aeruginosa is the commonest bacteria. The other important organisms are Klebsiella pneumoniae, E. coli, Acinetobacter species. Antibiotics showing high activity against Pseudomonas aeruginosa are Piperacillin tazobactam, Carbapenemase, and Quinolones. mucA gene mutation of P. aeruginosa could be used as predictors to identify poor prognosis in COPD patients. Analysis of antioxidant activity in Aegle marmelos shows 79.8% of reductions in DPPH free radicals for 100μg/ml. The minimum inhibitory concentration (MIC) value of the methanolic extract is around 256 μg/ml. 1mg/ml and 2mg/ml doses of the methanolic extract of this plant produced a positive relaxant effect in an isolated mouse bronchial rings, respectively. Conclusion: Methanolic extracts elicited the antagonistic effect against histamine and also relaxed the histamine-induced contractions, it can be concluded that relaxations induced by A. marmelos in mouse broncheal chain were due to the depression of H1-receptors. This study shows that Aegle marmelos can be effectively used in the treatment of COPD disorders.
Role of Adipokines in Obesity and Obesity related Metabolic Disorders
Authors: Govindaraj Jayamathi , Govindaraj Keerthidaa , Jayesh S. Raghavendra , Padmavathy Kesavaram , Ramalingam Mathangi , U. Vidyarekha
Published: August 2021

Obesity is defined as an excessive growth of adipose tissue. It is associated with over nutrition, which impairs systemic metabolic homeostasis. Adipokines secreted by adipose tissue could play an vital role in the development of obesity and associated metabolic disorders includes insulin resistance, inflammation, hypertension, cardiovascular risk etc. Adipokines will be of importance in the development of novel therapies for obesity-associated diseases. This review emphasises on obesity and the role of some Adipokines in obesity and related metabolic disorders.
Ceric Ammonium Nitrate supported on Hy-Zeolite Catalyzed Oxidative Condensation Reaction and its Docking Studies
Authors: R Sudha , G. Nithya , Devi P Brindha , Priyatharesini P. Indra
Published: August 2021

The chemistry of chalcone has been recognized as a significant field of study. Chalcone serve as to prepare starting materials for the synthesis of various heterocyclic compounds. From the backbone of reported literature, we have developed an alternative heterogeneous and simple catalytic system for the synthesis of chalcones via the oxidative condensation of benzyl alcohol with substituted acetophenone using metal nitrate supported HY-Zeolite as a catalyst. 30 mol% CAN supported HY-zeolite has been efficiently used as a catalyst for the oxidative condensation reaction of benzyl alcohol with substituted acetophenones in the presence of hydrogen peroxide as an oxidant in toluene to afford the corresponding chalcones in good to moderate yields. Docking studies were carried out for the synthesized compounds towards the protein Lysine aminotransferase using the software.
Platelet Refractoriness Evaluation after Platelet Concentrate Transfusion in Pediatric Leukemia
Authors: Murtasyidah Ana , Tambunan Betty Agustina , Andarsini Mia Ratwita
Published: August 2021

Platelet transfusion is being used in 67%-75% of hematology malignancies including leukemia. Platelet refractoriness is the failure to achieve satisfactory responses to platelet transfusions. Many transfusion centres use 1 hour and 24 hours after transfusion Corrected Count Increment (CCI) value to define platelet refractoriness. To analyze platelet refractory based on CCI-1h and CCI-24h value after Platelet Concentrate (PC) tranfusion in pediatric leukemia and the effect of non immune factors on platelet refractoriness. Subjects were evaluated for platelet count after 10-120 minutes and 18-24 hours of PC tranfusion to calculate CCI-1h and CCI-24h. Platelet Refractoriness was defined when CCI-1h <5×109/L and CCI-24h <4.5×109/L. Each subject was observed for non-immune platelet refractory factors. Interestingly, from 25 PC transfusion there was 20% platelet refractoriness of CCI-1h and 40% of CCI-24h. There was a significant difference CCI-1h and CCI-24h (p=0.027). Non immune factor had no effect for platelet refractoriness. Platelet count should be analyzed after 24 hours PC transfusion to diagnose platelet refractoriness. Further research including immune factor examination is needed.
GC-MS Identification of Anti-inflammatory and Anticancer Metabolites in Edible Milky White Mushroom (Calocybe indica) against Human Breast Cancer (MCF-7) Cells
Authors: S. Mohanasundaram , N. Rangarajan , V. Sampath , K. Porkodi , Dass Prakash M.V. , N. Monicka
Published: August 2021

Milky White Mushroom is a species of edible mushroom native to India. The Purpose of this study was to determine the anti-inflammatory and anticancer compounds from Calocybe indica. The ethanolic extract from Calocybe indica were prepared. GC-MS was performed and the major bioactive compounds such as polysaccharides, amino acids, sterols, phytol, and squalene were determined. Calocybe indica was analyzed for their antioxidant activity through In vitro assays such as Free radical activity on DPPH, Hydroxyl radical scavenging assay, Nitric Oxide scavenging assay, Superoxide scavenging assay. Anti-inflammatory effect was estimated by protein denaturation inhibition assay, Proteinase inhibition assay, Cyclooxygenase inhibition assay and Lipoxygenase inhibition assay. Anticancer activity of Calocybe indica extract showed maximum inhibition of 69.11% of growth of human breast cancer cell (MCF 7) at 100μg/ml exposure for about 72 hours. At the end of this study, it was indicated that ethanolic extract of Calocybe indica can be used as an anti- inflammatory and anticancer agent.
Hypolipidemic effect of prepared Polyherbal formulations in Wistar albino rats
Authors: Kumar Giri Ranjan , Kumar Kanungo Sunil , Kumar Patro Saroj , Sahoo Minaketan , Panda Dibya Sundar
Published: August 2021

Lipid lowering effect of polyherbal formulations using eight different plants was evaluated in triton and diet induced hyperlipidemic models of wistar albino rats. Formulations such as Tablet, Syrup and Suspension inhibited the elevation in serum cholesterol and triglyceride levels on Triton WR 1339 administration rats. The formulations at the same dose level significantly attenuated the elevated serum total cholesterol and triglycerides with an increase in high-density lipoprotein cholesterol in high-fat diet-induced hyperlipidemic rats. The standard drug Niacin showed slightly better effects. The treatment with herbal formulations produced 30-35 percentage improvement in oral glucose tolerance. Similarly all the formulations also reduced the elevated C-reactive protein which is a marker of Hyperlipidemia. In histopathological study it was found that treatment of polyherbal formulation significantly reduced the plaque size in aorta compared with HFD treated control group. The outcome of the study reveals the lipid lowering activity of polyherbal formulations in dyslipidaemic conditions by interfering with the biosynthesis of cholesterol and utilization of lipids.
The Prevalence Disability resulting from adult acquired Foot Flat Deformity among Middle aged population
Authors: M. V Sowmya , V Rajeswari.
Published: August 2021

Aim: To investigate about the prevalence of disability resulting from adult acquired foot flat deformity (AAFD) among middle aged population. Background: Adult acquired foot flat deformity (AAFD) which is also known as posterior tibialis tendon dysfunction (PTTD) is the condition which leads to pain due to the collapse of the longitudinal (length wise) arch of the foot. Its affects women more than non, peaking age of 55 years. The prevalence of flat foot is uncertain due to the lack of exact clinical or radiographic criteria. The foot structure problem which affects the functional activity in the adult population has been poorly studied. So the present study was undertaken about the prevalence of disability resulting from AAFD which may help to develop preventive approaches, as increased awareness serve to help the patient with earlier referral and treatment by limiting their disability. Methodology: 50 subjects who was diagnosed as AAFD was included in the study based on the inclusion and exclusion criteria. Foot function index score was calculated for the samples. Outcome Measure: Foot function index scale. Results: The total mean score is 112.75. The prevalence of disability resulting from adult acquired foot flat deformity which affects the quality of life for samples taken is 66%.
La Pandemia y el fin del mundo moderno
Authors: Gayozzo Piero
Published: August 2021

La modernidad proveyó nuevos ideales para la construcción de una sociedad más humanista. La globalización, la ciencia, la democracia y el progreso son sus marcas distintivas. Tras el brote de la pandemia producida por el SARS-CoV-2, los errores políticos de las últimas décadas se muestran y nuevas ideas de sociedad para tiempos posteriores a la modernidad surgen. En el siguiente artículo exploraremos los rumbos políticos que se proponen tras la pandemia tales como el capitalismo de vigilancia, el totalitarismo digital y los populismos aislacionistas. Finalmente se proveerá la necesidad de retomar los valores de la modernidad, una Nueva Ilustración, en aras de construir una sociedad global más humanista.
A comprehensive review of pharmacological and Analytical Aspects of Acacetin
Authors: Yao Liangliang , Zhu Suyou , Liu Wei , Manzoor Zahid , Nisar Muhammad Farrukh , Li Mingxi
Published: August 2021

Among the large group of natural polyphenolic flavonoids, acacetin is widely distributed throughout the plant kingdom and remained the part of the food and traditional medication systems across the globe. Acacetin is found naturally in more than 200 plant species belongs to 60 different plant families, but mostly in Asteraceae and Lamiaceae families in the genus of Artemisia, Cirsium, Dendranthema, Saussurea, Dracocephalum, and Origanum. In Traditional Chinese Medicine (TCM) system, plant extracts having acacetin with various biological activities are given to cure different ailments including microbial or viral infections, cardiovascular issues, blood glucose fluctuations or diabetes, neurological and immunological disorders, hyperlipidemia, chronic inflammations, cancers or tumor control, hepatic issues, and lot more to count. Acacetin mainly exerts its remarkable effects both at transcriptional as well as translational levels. Acacetin suppressed the phosphorylation of p38 mitogen-activated protein kinases (MAPKs) and nuclear factor (NF)-κB, and reduces lipid peroxidation through reactive oxygen species (ROS) scavenging capability. For many proteins and enzymes, acacetin directly binds with them to regulate their activities, and hence acts as a potent inhibitor of that particular function such as inhibition of sortase enzyme, translational protein enzymes, aldose reductase enzyme, inhibition of cell signaling channels and molecules, and much more. It is concluded that acacetin has the potential to use as a potent inhibitor of multiple proteins, enzymes, signaling molecules and ion channels. These properties make acacetin an appealing candidate to be designed and screened for use as a multipurpose inhibitor for diseases.
MORBIDITE ET MORTALITE CHEZ LES ENFANTS DE 01 A 59 MOIS HOSPITALISES AU SERVICE DE PEDIATRIE GENERALE DU CHU GABRIEL TOURE DE JANVIER A DECEMBRE 2013
Authors: Doumbia AK , Togo B , Togo P , Traore F , Coulibaly O , Dembele A , Maiga B , Dicko F , Diakité AA , Sylla M
Published: August 2021

Objectif : Ce travail visait à étudier la morbidité et la mortalité chez les enfants âgés de 01 à 59 mois hospitalisés dans le service de pédiatrie générale du CHU Gabriel Touré.Matériels et Méthodes : Il s'agissait d'une étude rétrospective, descriptive, sur une période de 12 mois allant du 1er  janvier au 31 décembre 2013.Résultats : Nous avons inclus 1625 enfants âgés de 01 à 59 mois soit 58% des patients hospitalisés. Le tiers des patients avait moins d'un an. Les garçons représentaient 57 % de notre échantillon avec un sex ratio de 1,33. La majorité des patients (83%) était issu de milieu social défavorisé. Les principaux diagnostics retrouvés étaient le paludisme (45%), les infections respiratoires aiguës (20,30%), et la malnutrition aiguë sévère (20,06%). Les patients guéris représentaient 82,3% et le taux de mortalité était estimé à 3,3%. La majorité des patients décédés était des filles (51%). Les décès étaient plus fréquents en juillet et aout. Les trois principales causes de décès étaient la malnutrition (47%), le paludisme (32%) et les infections respiratoires aigües (19%). Nous avons enregistré 48 sorties contre avis médical (3%) et 81 cas d'évasion (5%).Conclusion : La morbidité et la mortalité en pédiatrie restent préoccupantes dans notre pratique. Elles sont liées à des affections pour la plupart évitables par l'information, l'éducation et la communication.Mots clés : morbidité, mortalité, enfants, pédiatrie, Bamako.
Cervico-facial and thoracic cellulitis in a disadvantaged environment in Ségou, Mali.
Authors: Fofana Aminata , Keita Mohamed , Beye Seydina Alioune , Doumbia-Singaré Kadiatou , Dramé Boubacar M , Timbo Samba K , Diallo Boubacar K , Ag Mohamed Alhousseini
Published: August 2021

Cervico-facial and thoracic cellulitis is a cellular diffusion from an infectious focus to cellulo-adipose tissues.The objective of this work was to review the management of this condition, to describe the descriptive study of the factors favoring it, to describe our experience of cellulite management and to identify the factors favoring it. Prognostic factors.This was a retrospective and descriptive study from October 2015 to March 2016 at the Ccentre Hhospitalier Nianankoro Fomba de Ségou. It involved 09 patients, 05 men for 4 women. The front door was essentially dental. We noticed 02 pregnancy cases associated with cellulite. We observed cervical and thoracic necrosis in 6 cases and cervical swelling in 03 cases. Cervical swelling in 03 cases. (Review title of study)The treatment was medical based on a triple with antibiotic and surgical treatment in all cases. The surgical treatment consisted of debridement - excision of the necrotic tissues and abundant washing with hydrogen peroxide and Dakin with a multiple drainage. Thoracic drainage was performed in 3 patients.The progression was favorable in 7 cases with complete cure and 2 cases of death in a sudden death chart. Mediastinitis.Cervico-facial cellulitis is a serious pathology of the young subject that can be life-threatening in the absence of a fast and adapted and multidisciplinary care
MALARIA AND OFFICIER'S PHARMACISTS OF BAMAKO, MALI: KNOWLEDGE, ATTITUDES AND, PRACTICES
Authors: Diallo Tidiane , Denou Adama , Coulibaly BF , Dakouo Blaise , Coulibaly B , Loup-Rey J
Published: August 2021

Goal: The objective of our study was to assess the evolution of the knowledge and behavior of pharmacy pharmacists in the fight against malaria with a view to involving officer's pharmacists in the fight against malaria.Method: This was a cross-sectional descriptive study that took place in two phases in the private dispensaries of the Bamako district of Mali. The first phase of the study (initial investigation) took place from April to May 2014 and covered 55 pharmacists from communes III and VI in Bamako. The second phase (monitoring) took place from November 2014 to November 2015, after training of all dispensary pharmacists in the Bamako district in accordance with the PNLP guidelines, which concerned all pharmacists in the Bamako district.Result: This revealed that some indicators are significantly improved: possession of a national policy document; Knowledge of drugs recommended for simple malaria; Practice and sale of rapid diagnostic tests for malaria. Other indicators have increased: availability of ACTs; Sale of insecticide-treated mosquito nets; Behavior before a suspicion of simple malaria; Behavior before suspicion of severe malaria.Conclusion: Thus, an involvement of officer pharmacists in malaria epidemiological surveillance can significantly reduce malaria morbidity and mortality. We recommend to the pharmacists the dispensation of the antimalaria ones according to the recommendations of the national program of fight against the malaria.
Spinal tuberculosis : 12 years experience at a Tunisian center
Authors: Abdelmoula Leila , Ben Tekaya Aicha , Cheikhrouhou S , Saidane O , Mahmoud I , Tekaya R
Published: August 2021

Background: We aimed to describe clinical, laboratory, diagnostic and therapeutic features of spinal tuberculosis and to identify factors associated with unfavorable evolution.Methods: Diagnosis was based on microbiological evidence, and/or histopathological evidence of tuberculosis infection, or clinical and paraclinical data.Results: A total of 49 patients (26 females) were enrolled. The mean age of the sample was 51.84 years, and the mean duration from initial symptoms to the time of diagnosis was 6.65 months. A predisposing factor to infection was noted in 38.7% of patients. Lumbar vertebrae (67.3%) were the most commonly involved site of infection. Spinal tuberculosis was associated with 3 cases of peripheral arthritis and 13 cases of visceral involvement (seven pulmonary tuberculosis). Diagnosis was based on histopathological evidence in 9 cases. Computed tomography-guided percutaneous biopsy was performed in 36 patients, and was consistent with tuberculosis in 6/36 cases. Medical treatment alone was implemented in all patients, while 8 patients underwent interventional treatment. The mean duration of medical treatment was 13.59 months. The outcome was favorable in 84.2% of cases, without neurological sequelae. Presence of abscess, vertebral fracture on magnetic resonance imaging, initial blood cells counts ≥11.500/mm3 and spinal deformity were the predictors of unfavorable outcome.Conclusion: Spinal tuberculosis results in significant morbidity due to its insidious course and delayed diagnosis because of diagnostic and therapeutic challenges. Early establishment of definitive etiologic diagnosis and appropriate treatment is of paramount importance to prevent development of sequelae.
Semântica modal e coerência ideacional no particípio genitivo absoluto grego
Authors: Silva Fernando Henrique , Albuquerque Roque
Published: August 2021

O particípio genitivo absoluto (PGA) no grego é entendido como oração adverbial com a funções textuais: anáfora, mudança de referente, de cenário e de parágrafo. Argumentamos que essas funções textuais e os usos adverbiais ocorrem por um processo pragmático de inferência que leva em conta a semântica modal do particípio como pressuposição factível, a estrutura morfossintática do particípio genitivo absoluto e o conhecimento do leitor orientando-o na construção da coerência ideacional. Para isso usamos a Linguística Sistêmico-Funcional no grego de Atos dos apóstolos. Apresentamos a visão morfossintática do PGA como oração adverbial e a textual; depois a semântica modal. Em suma: a semântica e a morfossintaxe do PGA orientam o leitor nas inferências.
Moinha de carvão e bioestimulante vegetal na formação de mudas de cedro australiano
Authors: Coimbra João Vitor Mori , Lima Ana Paula Leite , Lima Sebastião Ferreira , Silva Lázara Daniela Dias , Kaneko Juliana Akemi
Published: August 2021

Com o objetivo de se avaliar o uso da moinha de carvão e do bioestimulante vegetal na produção de mudas de Toona ciliata foi instalado, em casa de vegetação, um experimento em blocos casualizados, em esquema fatorial, combinando cinco proporções de moinha adicionada ao substrato (0%; 7,5%; 15%; 22,5%; 30%), na presença e ausência de bioestimulante vegetal (10 mL L-1 de água) no tratamento das sementes, com 4 repetições. Decorridos 124 dias após semeadura foram analisadas as variáveis: altura (H) diâmetro de colo (DC), área foliar (AF), comprimento de raiz (CR), volume de raiz (VR), massa seca da parte aérea (MSPA), de raiz (MSR) e total (MST). Esses parâmetros foram utilizados para calcular as variáveis de qualidade de muda: relações altura/diâmetro (RHD), parte aérea/raiz (RPAR), altura/parte aérea (RHPA) e o Índice de qualidade de Dickson (IQD). A melhor proporção de moinha variou de acordo com o parâmetro avaliado, sendo que o seu uso em doses moderadas, associadas ao bioestimulante vegetal afetou positivamente o desenvolvimento das mudas. Isoladamente, o bioestimulante vegetal afetou negativamente a qualidade de mudas, e algumas variáveis mostraram-se mais sensíveis em proporções mais elevadas de moinha de carvão havendo um decréscimo mais acentuado das médias.
Análise dos discursos das juventudes escolares sobre sexualidades dialogadas na web rádio
Authors: Maia Samuel Ramalho Torres , Torres Raimundo Augusto Martins , Torres Joana  Darc Martins , Moraes Luna Morgana de Oliveira , Costa Isabela Gonçalves
Published: August 2021

O objetivo é analisar os discursos das juventudes sobre sexualidades mediados no Programa “Em Sintonia com a Saúde” veiculados na Web Rádio AJIR Método: Pesquisa documental e qualitativo realizada em 2017 e 2018 com 162 participantes de 6 escolas do Ceará. Elencou-se 24 perguntas-discurso que foram organizadas em categorias: 1) “Vícios” sexuais e masturbação; 2) Práticas sexuais “criminosas” e “bizarras”; 3) Saúde sexual e reprodutiva e relações de gêneros. foram analisadas tendo como ancoragem a análise do discurso de Michel Foucault. Resultados: A comunicação no ciberespaço da internet, as interações com a população juvenil sobre sexualidades e outros temas são dialogadas em várias mídias digitais. As juventudes produziram suas formas de dizer e ver as sexualidades, as práticas sexuais, a reprodução humana, “vícios”, tabus, preconceitos com os LGBTQIAP+. Conclusão: As interações com mediação na web rádio possibilitaram diálogos pedagógicos em saúde como práticas de cuidado de si e dos outros.
Proposições de práticas de inovação utilizando a avaliação de maturidade de gestão da inovação e boas práticas da literatura em uma empresa de software
Authors: Delesposte Jamile Eleutério , Aguiar Gustavo Jorge Martins , Oliveira Fernanda Uene Endson , Vieira Alex Martins , Sarruf Gabriel Francisco
Published: August 2021

A inovação se tornou algo indispensável para as empresas que pretendem se manter competitivas e sustentáveis. Com a gestão da inovação, é possível traçar um caminho mais estruturado para que as empresas conquistem vantagens competitivas e melhorias em seus resultados. Porém as organizações, principalmente as micro e pequenas, possuem dificuldade de avaliar as suas práticas de inovação, bem como de traçar planos viáveis para alcançarem melhores resultados. Diante dessa situação, o presente artigo tem como objetivo identificar o nível de gestão da inovação de uma empresa de software, a fim de detectar as principais deficiências por fundamentos da capacidade de inovação e resultados de inovação e propor práticas de inovação para sua melhoria. Para isso, foi utilizado o método de estudo de caso em uma empresa de software de pequeno porte localizada no interior do estado do Rio de Janeiro e foi aplicado o instrumento de avaliação do Prêmio Nacional da Inovação da Confederação Nacional de Indústria para identificação do seu nível de maturidade de gestão da inovação. Com o instrumento e o método implementados, foi possível identificar e priorizar as oportunidades de melhoria relacionadas à gestão da inovação, posteriormente, propor ações embasadas em referências bibliográficas reconhecidas nos temas abordados. Além disso, o procedimento metodológico implementado pode ser replicado em outras empresas para identificação de práticas de inovação e melhoria do seu nível de gestão da inovação.
Preditores de risco psicológico em Psicologia da Saúde: uma revisão da literatura
Authors: Paiva Camila Santos , Guimarães Valeriana Castro , Costa Neto Sebastião Benício , Porto Joana D'Arc Silvério
Published: August 2021

O ajuste psicológico é um fenômeno dinâmico e multidimensional, e não pode ser reduzido simplesmente a uma ausência de distúrbio psicológico. O sucesso dos cuidados psicológicos junto a enfermos crônicos inicia-se com a identificação das condições de risco e seus preditores. A compreensão do conhecimento acumulado e das evidências mais atuais sobre o tema favorece a elaboração do diagnóstico e no planejamento de ações.Objetivo:Realizar uma revisão integrativa dos fatores que influenciam o processo de adaptação psicológica e fatores de risco para morbidade psicológica e/ou psiquiátrica no adoecimento.Metodologia:Foi realizada uma busca da literatura especializada por meio de artigos científicos nas bases de dados: Portal de Periódicos Capes/MEC, BVS e PubMed utilizando os seguintes descritores: emotional adaptation and adjustment disorders and hospitalization and psychosocial impact.Resultados:A busca pelos descritores nas bases de dados selecionadas resultou em 1.368 artigos, que após a seleção por meio da aplicação dos critérios de inclusão e exclusão e triagem dos títulos, resumos e leitura completa, foram reduzidos a 54 artigos incluídos na análise. Os dados retirados dos artigos foram tabulados e analisados conforme a freqüência. Os principais resultados encontrados nos artigos foram analisados conforme método de análise de conteúdo proposto por Bardin. Conclusão: A Revisão da literatura possibilitou identificar os principais Preditores de Risco Psicológico em Saúde: sofrimento emocional, história prévia, percepção do diagnóstico/prognóstico, suporte social, fatores sociodemográficos e a forma com que a pessoa lida com o processo.
Ensino de matemática remoto: uma experiência inédita na educação básica
Authors: Costa Brunna Batista , Fernandes Lizandra dos Santos , Corrêa de Paula Marlúbia , Silva Flaviana dos Santos
Published: August 2021

Este artigo apresenta uma pesquisa com 30 professores de matemática de Educação Básica, em turmas do 6º ao 9º ano, de escolas públicas e particulares, que efetuam suas aulas por meio de ensino remoto, com o objetivo de saber o que esses professores consideram como dificuldade ou facilidade na realização do ensino remoto de matemática, em período de isolamento social. Trata-se de uma verificação qualitativa. Como instrumento de coleta de dados, utilizou-se um questionário com dez perguntas, enviado via Google Forms. Os professores foram convidados a participar desta investigação via redes sociais (WhatsApp e Facebook) com um alcance sobre oito estados brasileiros (RS, CE, SP, BA, RJ, MG, MT e MA). A partir dessas contribuições, aplicou-se a Análise Textual Discursiva que resultou em levantamento de categorias emergentes. Para concluir, pode-se afirmar a emergência de contribuições que sinalizem o reconhecimento de várias dificuldades que estão ocorrendo na realização desse ensino. Dentro dessa resultante, o vídeo utilizado como recurso didático parece funcionar como um conector entre todos os professores, pois foi o único recurso educacional considerado por todos como uma facilidade. Nesse quesito se insere tanto o vídeo pronto como aquele que é produzido pelo próprio professor de matemática.
O uso da análise textual discursiva para identificar categorias presentes numa universidade frente a múltiplas realidades
Authors: Corrêa de Paula Marlúbia , Guimarães Gleny Terezinha Duro , Nascimento Maria Manuel da Silva , Silva Ana Emanuelle Lisboa Campos , Silva Flaviana dos Santos
Published: August 2021

Este artigo tem como objetivo debater a expectativa de reinventar a sala de aula a partir da necessidade do uso massivo de computador e internet, nestes dias de isolamento físico, por parte de professores e alunos que têm tal acesso. Metodologicamente, o artigo descreve as expectativas de quatro alunos sobre o regresso da escola de Educação Básica no pós-pandemia. Através da metodologia de Análise Textual Discursiva, optámos por obter categorias emergentes. Os resultados confirmaram a necessidade de ainda repensar a formação, evitando maior expectativa sobre o uso de tecnologias do que sobre a prática pedagógica dos professores.
Universidade Pública em Ação: Projeto de extensão para formação de professores de matemática #COmVIDa
Authors: Paula Marlúbia Corrêa , Santana Eurivalda Ribeiro dos Santos , Couto Maria Elisabete de Souza , Correia Diná da Silva
Published: August 2021

Este relato de experiência descreve um projeto de extensão gerado em modo remoto, com características de on-line, por conta da pandemia (causada pelo coronavírus SARS-CoV-2), cuja formação ocorreu numa universidade pública do Sul da Bahia e cujo objetivo foi registrar os procedimentos de formação (professores de Matemática da Educação Básica; coordenadores; estudantes de graduação e bacharelado). Metodologicamente, essa ação foi organizada pelos docentes dos Departamentos de Ciências exatas e Tecnológicas e de Ciências da Educação e pertencentes ao Grupo de Pesquisa em Educação Matemática, Estatística e em Ciências. Os recursos tecnológicos mobilizados pela universidade pública pertencem à janela G-Suite (google classroom, google meet, e-mail, google forms) para estruturar um curso (50 vagas, 40h), por meio de três módulos voltados ao ensino de estatística. As considerações finais permitiram ratificar o interesse dos professores na participação dessa formação, pois o grupo de cursistas foi selecionado dentre 322 inscrições. Além de atender a esses professores, esta formação propiciou, em primeira mão, aos estudantes de graduação em matemática, a participação em todos os momentos de estruturação desta atividade junto aos docentes do grupo de pesquisa. Quanto aos cursistas, projeta-se a perspectiva de constituírem aprendizagens das quais decorrerá a identificação dos conceitos utilizados, bem como a exploração do desenvolvimento do sujeito em situação, obtendo, dessa fase, registros desses cursistas, para que, voltando-se ao ensino, possam adequar os conceitos estatísticos desenvolvidos nessa forma de conexão de conceitos que aqui se propõe.
Desenvolvimento de gráficos táteis de azulejos coloniais para a inclusão cultural
Authors: Maia Ivana Marcia , Silva Yasmin Sousa , Silva Yasmin Serra
Published: August 2021

O desenvolvimento desse estudo envolve a criação de gráficos táteis de azulejos coloniais, visando preservar, resgatar e tornar acessível a cultura para pessoas com cegueira ou de baixa visão. O estudo ou apreciação de obras de arte é um direito quase sempre inacessível para uma parcela considerável das pessoas com deficiência visual. No Brasil, ao longo dos anos tem sido instaurado um conjunto de normativas legais voltadas às pessoas com deficiências, almejando expandir as garantias de proteção e promoção social, como o Decreto nº 6.949/2009, que confere status de emenda constitucional à Convenção das Nações Unidas sobre os Direitos das Pessoas com Deficiência (BRASIL, 2011). Aproximadamente 23,9% da população do país declara ter algum tipo de deficiência, dentre elas: mental, motora, visual ou auditiva. Referente à deficiência visual, esta atinge 3,5% da população declaram ter (IBGE, 2010). Nesse contexto, a modelagem tridimensional, pode proporcionar a esta parcela da população brasileira o exercício de alguns dos seus direitos. A modelagem tridimensional, ou modelagem 3D, trabalha na construção de um objeto ou modelo tridimensional em um ambiente virtual, ou seja, com auxílio do computador. Esta tecnologia é crucial para a realização desta pesquisa na questão de proporcionar a apreciação dos azulejos presentes no centro histórico de São Luís, através da exploração tátil, também conhecida como “leitura com as mãos”. Assim, a pesquisa apresenta o desenvolvimento de azulejos tridimensionais no formato de gráficos táteis, utilizando a modelagem virtual e a impressão tridimensional dessas peças, permitindo a construção de uma imagem mental do ambiente ao qual fazem parte.
Design de Recursos Didáticos para Crianças com TEA
Authors: Maia Ivana Marcia , Silva Yasmin Sousa , Silva Yasmin Serra , Benitez Priscila , Soares André
Published: August 2021

O transtorno do espectro autista (TEA) é uma forma de desenvolvimento ao longo da vida definida por critérios diagnósticos que incluem déficits de comunicação social e interação social e padrões restritos e repetitivos de comportamento, interesses ou atividades (APA, 2013).  No Brasil estima-se que mais de dois milhões de pessoas tem Transtornos do Espectro Autista (TEA) (Paiva Junior, 2013). Sabe-se que tais transtornos se manifestam de forma individualizada e comprometem a comunicação e a socialização do indivíduo que os manifestam, o que torna desafiador o processo de sua inclusão social. Este projeto visa propor metodologia específica para o design gráfico de ferramentas voltadas ao ensino de crianças autistas. Pretende-se desenvolver conjuntos de atividades e disponibilizá-las nas versões física e digital. Dessa forma, será possível avaliar a resposta da criança autista quanto aos estímulos físicos e cognitivos, além dos aspectos relativos à aprendizagem.
Covid-19 pneumonia: Timing of pneumomediastinum and pneumothorax in 11 patients
Authors: Turk Mostafa Al , Mitri Maria , Jarrah Kawthar , Chebl Joanna Abi , Juvelekian Georges
Published: August 2021

Purpose: As the pandemic continues, many complications, previously recognized as rare, are now being reported as more than frequent complications of Covid-19 pneumonia. Of those, pneumomediastinum and pneumothorax are gaining attention. Their mechanism of occurrence/trigger is not fully understood, but the timing at which they occur is unclear.Methods: This is a case series of 11 Covid-19 patients with pneumomediastinum; retrospectively, we shed light on some of the patients’ characteristics, the role of mechanical ventilation, and the timing of pneumomediastinum after initiation of mechanical ventilation.Results: We found that despite following the lung-protective strategy and despite keeping a plateau pressure at an acceptable range, most of our patients had an acute event around the same timing of mechanical ventilation.Conclusions: The similar timing raises questions about other risk factors that remain unknown. Timing and steroids can contribute to the higher incidence of these complications.
Implant Placement in a Cemento-Osseous Dysplasia: A case report
Authors: Perez Alexandre , Maman Avigaïl , Donna Edouard Di , Lombardi Tommaso
Published: August 2021

We present a 45-year-old black woman diagnosed with a florid cemento-osseous dysplasia (FCOD) affecting the right lower quadrant and the anterior mandibular region. The patient requested dental implants to rehabilitate the edentulous central lower incisors area (teeth # 31 and # 41) corresponding to a periapical cemento-osseous dysplasia (PCOD). Successful osseointegration of the two implants was obtained using a two-step procedure in order to limit the risk of complications associated with implant placement. Follow-up at one year showed no recurrence and good implant stability. Due to the abnormal quality of the bone in cemento-osseous dysplasia (COD), implant placement is generally avoided, and no other case reports have been reported in the literature in patients affected by PCOD. The present case suggests that in an appropriate clinical setting, implant placement may be a successful procedure.
Wild Plants Used as Vegetables by Transhumant People Around the Georgia–Turkey Border in the Western Lesser Caucasus
Authors: Kazancı Ceren , Oruç Soner , Mosulishvili Marine , Łuczaj Łukasz
Published: August 2021

Recent ethnobotanical studies in the Caucasus, mainly in Georgia, reveal the significant ethnobotanical knowledge of local people related to wild edible plants. However, few studies have been conducted in the Lesser Caucasus, west Georgia, and Turkish Caucasus. This study aims to represent and evaluate the cultural importance of wild vegetable plants and their patterns of use along the Georgia–Turkey border. During the transhumance period in the summers of 2017 and 2018, 104 participants (65 in Turkey and 39 in Georgia) were interviewed using a semistructured questionnaire. The Cultural Importance Index and Relative Frequency of Citation were used to compare the relative importance of species in each region. The use of 83 wild plant species from 23 plant families as vegetables was documented, with 45 species recorded in Georgia and 72 species in Turkey. One-third of the recorded wild plant species and 52 use instances out of 122 species-use combinations were shared on both sides of the border. Women and men had mentioned almost the same number of species, and there was a nonsignificant correlation between the plant knowledge and age. Although there were no significant differences in the plant parts used, the way people used plants as vegetables varied significantly across the border. Considering the floral similarity across the border, the number of species used in common and shared vegetable plant knowledge was quite low. There is not a significant difference between the two countries in terms of the most frequently cited and culturally important species (
Rumex
,
Urtica
, and
Polygonum
spp.). However, the recognition of some of the most important shared species (
Heracleum
,
Chaerophyllum
,
Arctium
, and
Campanula
spp.) diverged significantly in different administrative regions.
Diagnóstico, intervenção precoce e prevenção do Delirium no adulto
Authors: Almeida Luciana , Martins Sónia , Marins Nivaldo , Fernandes Lia
Published: August 2021

Introdução: O delirium é uma síndrome frequente, com morbimortalidade associada considerável mas potencialmente prevenível se instituídas medidas de prevenção e rastreio adequadas. No entanto, é ainda pouco conhecida e muitas vezes subdiagnosticada, principalmente na Atenção Primária à Saúde onde está muitas vezes associado a internamento recente e situações benignas facilmente corrigíveis se detetadas precocemente. O objetivo deste trabalho foi a realização de uma revisão sobre o delirium, assim como propor uma abordagem diagnóstica, terapêutica e preventiva na Atenção Primária à Saúde. Métodos: Foi feita uma pesquisa bibliográfica  de artigos publicados entre janeiro de 2008 e dezembro de 2020, na PubMed e Scielo com o descritor “delirium” combinado com “primary health care” ou “general practice”. Resultados: Na abordagem do delirium, importa primeiro identificar indíviduos de risco, tarefa que tem por base um modelo multifactorial que conjuga fatores predisponentes e precipitantes. Em termos de métodos de rastreio, o mais usado é o Confusion Assessment Method, mas testes de avaliação da atenção ou Escala de Agitação e Sedação de Richmond podem também ser usados, sempre em associação com o exame físico completo para confirmação diagnóstica. A abordagem terapêutica e preventiva assenta essencialmente em medidas não farmacológicas que visam corrigir fatores de risco. Considerações Finais: De uma forma geral, o desenvolvimento de programas sistemáticos de formação e rastreio que envolvam uma equipa multidisciplinar, incluindo elementos da Atenção Primária à Saúde e cuidadores, podem ser a chave para o sucesso na redução da incidência do delirium e das suas consequências.
Case Report: A Pediatric COVID-19 Patient with Pyelonephritis and Febrile Seizure as a Rare Clinical Manifestations
Authors: Rezagholizamenjany Masoud , Yousefichaijan Parsa , Shariatmadari Fakhreddin , Kahbazi Manijeh , Falahati Vahid , Gandi Yazdan , Nazari Javad
Published: August 2021

: In this study, we report a rare presentation of COVID-19 virus, as febrile seizure. The patient was a 13-month-old girl with febrile seizure. Fever of the patient had started three days ago. Also, the patient had chills for five minutes in addition to cyanosis and tachycardia. On the primary evaluation, active urine analysis showed pyelonephritis. After a complete evaluation, the patient was diagnosed as a positive COVID-19 case based on polymerase chain reaction using nasopharyngeal and oropharyngeal swabs.
Study of Obtaining Informed Consent in Pediatric Wards from the Viewpoint of Physicians and Children’s Parents
Authors: Rezvani Soodabeh , Fadavi Mohsen , Bazmi Shabnam
Published: August 2021

Background: Obtaining informed consent for diagnostic and therapeutic procedures is of great moral and legal importance, which is more important in the field of pediatrics due to its specific issues. Objectives: Obtaining informed consent in the pediatric field is specific because of many factors, including the age of the patients and the necessity of obtaining consent from parents or legal guardians. This study aimed to evaluate the process of obtaining informed consent from the viewpoint of substitute decision-makers (parents or guardians) and physicians. Attention to the differences between the views of these two groups by establishing appropriate and correct communication skills between them can lead to greater satisfaction and increased effectiveness of treatments. Methods: In this descriptive study, the data were collected through questionnaires completed by 188 parents and 23 physicians. Finally, the statistical analysis was conducted using the one-sample t test method in SPSS 16. Results: In 96.3% of the cases, parents believed that where the patient, their relatives, and the medical team disagreed about the kind of treatment, the final decision was made by the medical team. One-third of them did not receive enough information or received no information at all. Informing parents about other possible treatments, complications of the procedures, considering the patients and their relatives’ opinions for the final decision, informing the child about his/her disease and treatment plans, and informing the parents about the possible outcomes were not in the favorable range. Physicians believed that decision about the treatment was made based on the opinion of the parents and the clinical committee, and only in 3.4% of the cases, their opinion was the basis for decision-making. Conclusions: The results showed that there was a gap between the parents and physicians’ opinions about informed consent, as the physicians believed that they act as the patients’ parents wish and the parents believed that their opinion played no important role in the final decision regarding the health of their children. Thus, it seems necessary to institutionalize the culture of participatory decision-making by physicians and parents in decisions related to the diagnosis and treatment of children, and more emphasis should be placed on establishing the right relationship between treatment staff and patients and their relatives.
Homologies in Freud and Derrida
Authors: Dwivedi Divya ,   Philosophy Documentation Center
Published: August 2021

Freud’s late works established the schema of a more or less inexorable civilizational course built around one drive—the death drive—despite his emphatic insistence on a dual structure of two drives. This schema became influential for Critical Theory and in a more subterranean way, also for decolonial thought, and has been widely invoked during the pandemic. It indicates the extent to which drive, destruction, and mastery have consolidated into a , which not only fails to be dislodged by but even informs Derrida’s readings of Freud. Instead, we have to be attentive to the play of homology in Freud as of life, psyche, and civilization, as archaic inheritance. Freudian homology distinguishes itself from what Derrida called “genealogical drive.” The Freudian assumptions in this regard need to be addressed in a step beyond which works with a concept of origin—as its own interruption—that can neither comprehend nor deconstruct the concept of origin as a single and perpetually active homological power as is to be found in Freud.
Resisting “Forgiveness Oppression”
Authors: Benson Bruce Ellis ,   DePaul University
Published: August 2021

Victims of abuse and violence are often pressured to forgive their perpetrators. The idea of unconditional forgiveness—forgiveness granted regardless of apology, remorse, or change of behavior—has become a norm for many in the west and those who refuse to forgive are often seen as resentful and bitter. Yet those imploring forgiveness are often the powerful and those asked to forgive are often minorities who have comparatively little power. Since forgiveness in western culture derives from Jesus’s teachings, I return to those teachings. While the verse “Father, forgive them; for they do not know what they are doing,” is often cited as what Jesus taught, the reality is that his teaching about forgiveness is strongly connected to repentance or remorse. I show how those teachings have been significantly distorted to create the norm of unconditional forgiveness. Finally, I consider the value and place of resentment.