bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Type and Volume Content of Steel Fiber on the Compressive Strength of Ultra-High Performance Fiber Reinforced Concrete
Authors: SOLOVIEV V.G. , MATIUSHIN E.V. , EFISHOV L.I.
Published: February 2024

The paper presents the results of determining the compressive strength of various compositions of Ultra-High Performance Fiber Reinforced concrete (UHPFRC) with fiber volume content from 1 to 3%. Four types of fibers were used: corrugated fiber of 15/0.3 mm and 22/0.3 mm, straight fiber of 13/0.3 mm and hooked-end fiber of 30/0.5 mm. It was found that corrugated and hooked-end fiber leads to an increase in compressive strength by 10–30 MPa when its content is increased from 1 to 3%. Straight fiber has no noticeable effect on the mechanical properties of UHPFRC. Empirical equations for predicting the compressive strength of UHPFRC depending on the strength of concrete matrix, geometric dimensions and content of dispersed reinforcement for compositions with corrugated and hooked-end fibers have been obtained. It is found that increasing the volume content of aggregate in the concrete matrix composition from 0.2 to 0.4 m3/m3 leads to an increase in the strength of UHPFRC. The strength of specimens with corrugated fiber increased by 5.3–13.3 MPa, with hooked-end fiber – by 14–19.3 MPa, with straight fiber – 5–7 MPa. It is also noted that the most intensive growth of mechanical characteristics due to the increase in the aggregate volume content in the composition is observed at a higher percentage of fiber volume fraction.
Evaluation of the Quality of Wood Impregnation with Inorganic Fire Retardants During Autoclaving
Authors: FEDOSOV S.V. , LAZAREV A.A. , TCVETKOV D.E. , KOTLOV V.G. , KOMLEV A.Yu.
Published: February 2024

The problem of determining the depth of impregnation of wood with an aqueous solution of sodium bicarbonate is considered. The relevance of the study is due to the need to develop a method of non-destructive testing of wood impregnated with flame retardants in order to identify industrial defects and (or) counterfeit products. The authors of the article propose a method for determining changes in the concentration of sodium bicarbonate in flushes from wood layers when impregnated with a nine percent solution of this salt under various conditions of treatment in an autoclave. In the work on determining the depth of impregnation with a nine percent sodium bicarbonate solution of wood during autoclave treatment, an experiment was conducted. Within the framework of this experiment, it was planned to confirm or refute the working hypothesis about the presence of anisotropy of wood by layer-by-layer examination of the depth of its impregnation with an aqueous solution of sodium bicarbonate in layers when they are obtained by sawing along and across the fibers. It was also planned to develop a methodology for conducting a study of samples of wood layers impregnated with a nine percent aqueous solution of sodium bicarbonate under various autoclaving conditions. It was also necessary to establish a pattern of changes in the concentration of sodium bicarbonate in flushes from wood layers with appropriate flame retardant treatment. The authors also planned to obtain equations to describe the dynamics of changes in the concentration of sodium bicarbonate in flushes from impregnated wood layers under various autoclaving conditions. The results of this experiment made it possible to obtain an equation of the dynamics of the change in the mass fraction of sodium bicarbonate in the flushing from the wood layer in the longitudinal section from the sample. The value of the coefficient of determination for the resulting equation is determined. When layer-by-layer examination of the depth of impregnation of wood with an aqueous solution of sodium bicarbonate, anisotropy was observed in the cuts of layers along and across the fibers.
Book and Film Reviews
Authors: Tēraudkalns Valdis , Harvey Graham , Lazzaretti Vera , Dias Nélia , Janzen Rebecca , Lanzillo Amanda , Fuchs Sandhya , Slatoff Zoë , O'Brien-Kop Karen , Liu Lu , Guglielmi Marco , Coville Elizabeth , Donzelli Aurora , Rappoport Dana
Published: February 2024

ALTNURME, Riho, ed., Old Religion, New Spirituality: Implications of Secularisation and Individualisation in Estonia. xii, 185 pp., 6 tables, 1 map, references, index. Leiden: Brill, 2023. Paperback, $54. ISBN: 978-90-04-52446-0.

CHAMEL, Jean, and Yael DANSAC, eds., Relating with More-than-Humans: Interbeing Rituality in a Living World. xvi, 254 pp., 25 b/w ills., index London: Palgrave Macmillan, 2022. Hardback, $129. ISBN: 978-3-031-10293-6.

CHATTERJEE, Moyukh, Composing Violence: The Limits of Exposure and the Making of Minorities, 184 pp., 6 ills., bibliography, index. Durham, NC: Duke University Press, 2023. Paperback, $24.95. ISBN: 978-1-4780-1966-4.

De JONG, Ferdinand, and José MAPRIL, eds., The Future of Religious Heritage. Entangled Temporalities of the Sacred and the Secular, 244 pp., 6 b/w ills., bibliography, index. London: Routledge, 2023. Hardback, $160. ISBN: 978-1-03-202194-2.

KING, Rebekka, ed., Key Categories in the Study of Religion: Contexts and Critiques, 246 pp., 4 b/w figs., references, index. Sheffield: Equinox Publishing, 2022. Paperback, $35. ISBN: 978-1-78179-966-6.

KHOJA-MOOLJI, Shenila, Rebuilding Community: Displaced Women and the Making of a Shia Ismaili Muslim Sociality, 280 pp., 32 b/w ills., bibliography, index. Oxford: Oxford University Press, 2023. Paperback, $29.95, ISBN: 978-0-19-764203-0.

LAZZARETTI, Vera, and Kathinka FRØYSTAD, eds., Beyond Courtrooms and Street Violence: Rethinking Religious Offence and Its Containment, 114 pp., illustrations, bibliography, index. London: Routledge, 2022. Hardback, $136. ISBN: 978-1-03-225265-0.

O'BRIEN-KOP, Karen, Rethinking ‘Classical Yoga’ and Buddhism: Meditation, Metaphors and Materiality, 280 pp., 10 b/w ills., appendices, bibliography, index. London: Bloomsbury Academic, 2023. Paperback, $39.95. ISBN: 978-1-350-23003-3.

Author's response to Zoë Slatoff's book review of Rethinking ‘Classical Yoga’ and Buddhism: Meditation, Metaphors and Materiality

ORELLANA, Marjorie Elaine Faulstich, Mindful Ethnography: Mind, Heart and Activity for Transformative Social Research, 186 pp, 4 b/w ills. London: Routledge, 2020. Paperback, $59.95, ISBN: 978-1-138-36104-1.

TATEO, Giuseppe, Under the Sign of the Cross: The People's Salvation Cathedral and the Church-Building Industry in Postsocialist Romania, 256 pp., 28 ills., bibliography, index. New York: Berghahn Books, 2020. Hardback, $135. ISBN 978-1-78920-858-0.

Dana RAPPOPORT, dir., Death of the One Who Knows. 82 mins. In Toraja and Indonesian, with English subtitles. Sulawesi, Indonesia (Le Miroir, Gabriel Chabanier; Planimonteur; Centre Asie du Sud-Est), 2021. Available through Documentary Educational Resources.
Protection of Rights of the Crimean Tatars as an Indigenous People of Ukraine in the International Arena
Authors: Dukach Nataliia
Published: February 2024

The purpose of this article is to study the main types and forms of participation of the Crimean Tatar people aimed at protecting the rights of the Crimean Tatars as an indigenous people of Ukraine in the international arena after the occupation of the peninsula in 2014. The article analyzes the problem of violations of international human rights law and the rights of indigenous peoples on the territory of the occupied peninsula. The paper outlines the main types and forms of participation of Crimean Tatars aimed at protecting the rights of indigenous people in the international arena, in particular, the participation of the Mejlis as a representative body of Crimean Tatars, as well as leaders of the Crimean Tatar indigenous people and human rights organizations, etc. The author also provides a list of international documents adopted since the beginning of the occupation of Crimea, which were adopted as a sign of support for Ukraine and condemnation of Russian aggression and occupation of Crimea and criminal actions of the Russian authorities. The author concludes that such participation of the Crimean Tatar indigenous people, aimed at protecting the rights of the indigenous people of Ukraine in the international arena, has become an important element of Ukraine's diplomatic struggle for Crimea. It is also emphasized that cooperation between Ukraine and the Crimean Tatar indigenous people is an important guarantee of the future processes of de-occupation and reintegration of Crimea, as well as the preservation of Ukrainian statehood on the peninsula.
Deployment of the Deliberative Model of Political Participation of EU Citizens in the Discourse of the European Democracy Future
Authors: Rotar Nataliia
Published: February 2024

The article investigates the process of deployment of the deliberative model of political participation of EU citizens in the discourse of the future of European democracy, which was officially defined by the EU at the organizational level (Conference on the Future of Europe), but the thematic content of the problem was not limited to any official documents, so every EU citizen got the opportunity to express an idea and participate in the discussion of the ideas of other subjects of deliberation at the first stage of the Conference (Multilingual digital platform).

The study of the application of digital tools of political participation in the practices of deliberative democracy, applied during the Conference on the Future of Europe, proved that two formats of such tools were used: first, the format of the Multilingual Digital Platform functioned according to the digital model of the deployment of political participation; secondly, the format of the European Citizen Panels was based on a mixed model that combined the principles of digital and face-to-face communications in the deliberation process. At the same time, both formats most systematically reflect the nature of the transformation of the discursive model of political participation of EU citizens from dialogic to deliberative forms based on digital tools.

The study of the forms of deliberation on the future of European democracy during the Conference on the Future of Europe and its results allows us to conclude that structurally, the problem of European democracy was defined by EU citizens as a set of interdependent dimensions promising for a common political agenda: elections to the European Parliament; EU federalization; political participation of citizens and consultations; institutional reforms; promotion of common European identity and common public space; protection and strengthening of democracy.

The established set of markers, thematic areas and clusters of the deliberation of the future of democracy at the second European Citizen Panel was reflected in 39 guidelines proposed for the development of the final recommendations of the Conference: ensuring rights and (non)discrimination – 9 guidelines; protection of democracy and the rule of law – 5; reforming the EU – 10; formation of European identity – 9; citizens' participation – 6. In the final documents of the Conference, a consensus was reached on 5 proposals, which accumulated most of the recommendations of citizens regarding the future of European democracy, expressed during the deliberation process.
Azerbaijan – Armenia – Georgia: Challenges and Prospects of Interstate Cooperation
Authors: Vasadze Gela , Nechayeva-Yuriychuk Nataliia
Published: February 2024

In the conditions of the ongoing Russian-Ukrainian war, the question of the future world order is more than urgent. The introduction of the sanctions regime against Russia led to the intensification of the latter’s efforts in the direction of creating its own ecosystem of survival, in which the states of the South Caucasus, in particular, the former Soviet republics such as Azerbaijan, Armenia, Georgia, are considered indispensable components. In their research, the authors analyze the features of the socio-political development of the named states of the South Caucasus in its relationship with the events of the Russian-Ukrainian war and changes.

The authors draw attention to the importance of the South Caucasus for ensuring the ability of the Russian Federation to continue the war against Ukraine at the current stage. In its desire to regain its status as a world leader, the Russian Federation is trying with all its might to preserve the existing status quo in the region, on the one hand, while simultaneously improving its relations with Turkey and Azerbaijan, on the other. The latter was quite clearly revealed during the Second Karabakh War in 2020 and the events of September 19, 2023 in Nagorno-Karabakh. The return of Nagorno-Karabakh to Azerbaijan due to the termination of the existence of the NKR from January 1, 2024 opens up new prospects not only for regional development, but also for the resolution of other “frozen” conflicts created by Moscow.

Eliminating the factor of military confrontation from the regional order is an important element of geopolitical stability and security in the region. And Georgia in this case plays an important role, on the one hand, as a potential mediator, and on the other, as a state that has a strategic partnership with Azerbaijan and good-neighborly relations with Armenia.
A importância dos sentimentos existenciais para a compreensão da enfermidade
Authors: Rossi Anhanha Brenda
Published: February 2024

Ao contrário das emoções, os sentimentos existenciais não são dirigidos a um objeto ou situação específica, mas são o pano de fundo afetivo através do qual a experiência como um todo é estruturada. Adicionalmente, os sentimentos existenciais são sentimentos corporais. Nesta direção, o presente artigo tem como objetivo apresentar a teoria dos sentimentos existenciais desenvolvida por Matthew Ratcliffe em Feelings of Being: Phenomenology, psychiatry and the sense of reality (2008) e o seu vínculo à noção de “dúvida corporal” desenvolvida por Havi Carel em Phenomenology of illness (2016), a fim de explicitar a importância dos sentimentos existenciais para a compreensão da experiência da enfermidade. O artigo é dividido em três seções: 1) Caracterização da natureza das emoções e dos sentimentos; 2) Caracterização dos sentimentos existenciais a partir da fenomenologia da experiência táctil, bem como a distinção entre sentimento existencial, emoção e sintonia afetiva; 3) Análise da alteração dos sentimentos existenciais pela dúvida corporal.
Tobacco Smoking-Attributable Mortality in Kenya: 2012 – 2021
Authors: Odeny Lazarus , Gathecha Gladwell , Mwenda Valerian , Kendagor Anne , Cheburet Samuel , Mugi Beatrice , Mithi Caroline , Jaguga Florence , Okinda Kennedy , Mohamed Shukri , Ong’ang’o Jane Rahedi
Published: February 2024

BACKGROUND: Tobacco smoking poses a significant risk for various diseases, including cardiovascular diseases, chronic respiratory diseases, and cancers. In Kenya, tobacco-related deaths contribute substantially to non-communicable disease mortality. This study aims to quantify the mortality attributed to tobacco smoking in Kenya from 2012 to 2021.

METHODS: Employing a prevalence-based analysis model, the study utilized Population Attributable Fraction to estimate age-specific Smoke Attributable Mortality (SAM) rates for individuals aged 35 years and older. Causes of death associated with tobacco use, including cancers, cardiovascular diseases, respiratory diseases, tuberculosis, and diabetes, were analyzed based on age, sex, and death records between 2012 and 2021.

RESULTS: Over the study period, 60,228 deaths were attributed to tobacco-related diseases, with an annual increase observed until 2016 and subsequent fluctuations. Respiratory diseases, diabetes mellitus, malignant cancers, tuberculosis, and cardiovascular diseases collectively accounted for 16.5% of deaths among individuals aged 35 and older. Notable contributors were pneumonia and influenza (respiratory diseases), oesophageal cancer (cancers), and cerebrovascular diseases (cardiovascular diseases).

SMOKING PREVALENCE: Smoking prevalence in Kenya indicated 17.4% of men, 0.9% of women, and 9% overall as current smokers. Former smokers constituted 10.6% of men, 1.4% of women, and 5.9% overall.

SMOKING-ATTRIBUTABLE MORTALITY: Out of observed deaths, 16.5% were attributed to smoking, with respiratory diseases (40.5%), malignant cancers (31.4%), tuberculosis (13%), cardiovascular diseases (8.9%), and diabetes mellitus (6.1%) contributing. Pneumonia and influenza, oesophageal cancer, chronic airway obstruction, and tuberculosis were primary causes, comprising 70% of all Smoking-Attributable Mortality (SAM).

DISCUSSION: The study underscores smoking's substantial impact on mortality in Kenya, emphasizing the urgency of preventive measures and tobacco control strategies. The findings highlight the differential contributions of smoking to various diseases, indicating the need for targeted interventions tailored to specific health outcomes.

CONCLUSION: Tobacco-related mortality is a significant public health concern in Kenya. Efforts should focus on preventing tobacco use and managing associated disease burdens. Smoking cessation initiatives and comprehensive tobacco control measures are imperative to mitigate the impact on population health.
The Functional Role of the Standing Deposit Facility in Inflation Management
Authors: Belavadi Dr Nikhil
Published: February 2024

In the context of controlling inflation within the economic framework, this study examines the fundamental role of the Standing Deposit Facility (STANDING DEPOSIT FACILITY). The investigation centres on the Reserve Bank of India's (RBI) approach and looks into the STANDING DEPOSIT FACILITY's functionality and efficiency in clearing up excess liquidity from the market. The research emphasizes the connection between the RBI's commitment to long-term economic stability and the operational stability of the STANDING DEPOSIT FACILITY through a thorough analysis of inflation patterns and STANDING DEPOSIT FACILITY rates over an extended period of time. The findings make clear how the STANDING DEPOSIT FACILITY influences the control of inflationary pressures and the upkeep of a robust economic environment, underscoring its importance as a tactical instrument in the central bank's monetary policy toolkit.
Effect of novel human milk oligosaccharides-based human milk fortifier containing lactoferrin, docosahexaenoic acid, and arachidonic acid on the growth of preterm infants with birth weight of 700–1800 g
Authors: Sengupta Amitava , Lal Ajay , Bhayana Harsh
Published: February 2024

Background: Premature infants with low birth weight are at risk of growth failure and neurodevelopmental impairment. Human milk oligosaccharides (HMOs) are bioactive components of human milk that may enhance growth and development. The novel HMO-based human milk fortifier (HMoF), which also contains lactoferrin, docosahexaenoic acid (DHA), and arachidonic acid (ARA), can help provide a safer nutritional option for the growth of premature infants. Materials and Methods: We conducted a non-comparative observational study using data from multiple centers that used novel HMO-based HMF (HMoF) in premature infants (n=14) with birth weights of 700–1800 g. The primary outcome of the study was to assess tolerability (in terms of feed tolerance), and secondary outcomes included growth outcomes defined by weight, length, and head circumference during the stay in the NICU and at discharge. Results: A cohort consisting of 14 infants with a mean gestational age of 30.21±2.04 weeks and a birth weight of 1246.36±39.98 g comprised the study. During the study period, incidences of feed interruptions due to feed intolerability were nil, and no infant presented with any signs of adverse effects. The novel HMO-based HMF (HMoF)-fed infant cohort had a mean weight gain of 21.89±5.23 g/day, a mean length gain of 1.01±0.48 cm/week, and mean head circumference gain of 0.89±0.32 cm/week. The mean growth velocity recorded was 16.03±1.73 g/kg/day. Conclusions: Novel HMO-based HMF (HMoF) containing lactoferrin, DHA, and ARA demonstrated acceptable feed tolerance and weight gain without any clinically significant adverse effects. Data indicates that the novel HMoF containing lactoferrin, DHA, and ARA is a safe option for supporting the growth of preterm babies. However, further studies are needed to compare novel HMO-based HMF (HMoF) with standard HMF in a randomized controlled trial.
THE FACTORS OF DEVELOPMENT OF THE IT-SECTOR IN TIMES OF ECONOMIC INSTABILITY: THE EXAMPLE OF HUNGARY AND BULGARIA
Authors: Шаповал А.В. , Якубовський С.О.
Published: February 2024

The article presents the results of a study of the dependence of the annual turnover of the IT segment in Hungary and Bulgaria on groups of factors with the definition of the most influential groups for each country separately. The analysis of the IT/ITC sectors of the countries in terms of economic efficiency and the quantitative indicator of companies is presented in general. An indicator of the dimension of companies for each of the countries is also presented. The main indicator of the financial efficiency of companies for both countries was the annual turnover of companies. Three main areas were classified as groups of influence: tax rates, educational component indicators, and labor force indicators. Tax rates were considered under three main types: corporate tax, payroll tax, and social contributions. The educational component as a group of factors was divided into two subgroups: the quantitative characteristics of students, graduates, and education costs. The group of labor force factors was based on analyzing the number of employees in IT/ITC and company-level staff costs. Based on correlation regression and vector autoregression, each influencing factor group was analyzed when creating optimal models. Based on econometric analyzes and tests (for example, the Granger test), systems of factors influencing the performance indicator of technological companies in Hungary and Bulgaria were derived.
Barreras al comercio de servicios medioambientales
Authors: Lasheras Sancho Laura
Published: February 2024

El comercio de servicios medioambientales, como los servicios de abastecimiento de agua o los servicios de operación y mantenimiento de instalaciones de energías renovables, es una herramienta fundamental para que los países puedan cumplir con objetivos de mitigación y adaptación al cambio climático. Sin embargo, las empresas exportadoras de este tipo de servicios suelen enfrentarse en el país de destino a barreras no arancelarias de naturaleza muy dispar. En este trabajo se ha pretendido hacer un análisis de dichas barreras. Del análisis realizado se desprende que la mayoría de barreras afectan a los modos de suministro a través de presencia comercial y presencia de personas físicas. Por otro lado, aunque se trate en muchos casos de barreras horizontales, las barreras relacionadas con contratación pública, la movilidad de profesionales o las malas prácticas administrativas afectan especialmente a la exportación de los servicios que han sido objeto de estudio en este trabajo.
Efficacy of growth regulators for maize fields
Authors: Tkalich Y. I. , Tsyliuryk O. I. , Kokhan A. V. , Yevtushenko H. O. , Gonzalez P. H.
Published: February 2024

At the current stage of agricultural development, it is paramount to introduce advanced technologies for maize cultivation. Special attention is required for the use of modern growth regulators in order to ensure stable increase in grain production. To protect maize from stress factors emerging in unfavorable meteorological conditions of the steppe zone (such as drought, high temperatures, negative impacts of pesticides, diseases, etc.), increasing attention is given to the application such physiologically active compounds as plant-growth regulators (PGRs). The experimental studies were carried out in 2021–2023 on the experimental field of the Dnipro State Agrarian-Economic University. The objective of the study was to identify the efficacies of the plant-growth regulators used in different doses on maize. The highest efficacy in the technology of maize cultivation was achieved by treating the maize plants with humates during the phase of 3–5 leaves. This treatment promoted a stable tendency towards growth, resulting in 5–7 cm increase in height (2.1–2.8%), 5–6% increase in leaf surface area, and increases in yield structure (13.6 cm in the cob length (5.1%), 18 grains (3.9%) in cob grain filling, and 29 g (9.1%) in mass of 1,000 grains), compared with the control without growth regulators. Somewhat lower efficiency according to all the aforementioned parameters was demonstrated by coating of seeds. Treatment of the seeds with growth regulators and microbial fertilizers in the phase of 3–5 leaves resulted in 7.3% to 18.7% increase in the yield, indicating their high efficacy, especially in unfavorable weather conditions. Therefore, the greatest gains in the grain yield was seen after using humate 400 g/ha + polyethylene glycol 360 g/ha – 1.08 t/ha; humate 800 g/ha + polyethylene glycol 240 g/ha – 1.19 t/ha; sodium metasilicate 600 g/ha – 1.23 t/ha; Pakt 500 g/ha – 1.23 t/ha; and Peram 100 mL/ha + Vympel PGR 500 g/ha – 1.12 t/ha. That is, of the sixty seven tested combinations of physiologically active compounds, no variant produced a grain-yield increase lower than 0.5 t/ha, and the variants with foliar feeding of the maize demonstrated no clear upward tendency in the yield after the PGRs had been introduced in doses above the norms. Studies of efficiency of the growth regulators and microbial fertilizers for maize confirmed that achievement of maximum grain yield is possible only by optimizing the vital factors at all stages of organogenesis of maize. When climatic elements develop with various amplitudes during a vegetative period, effectiveness of preparations is determined by their ability to enhance tolerance to the environmental stressors.
Authors: Usman Rahmawati A. , Syamsuddin Fadli , Ayuba Asni
Published: February 2024

Introduction: BPH or Benign Prostate Hyperplasia is a condition in which the prostate gland enlarges, extends upward into the bladder and blocks the flow of urine by closing the urethral orifice. TURP is one of the surgical procedures for BPH patients. Surgery causes actual and potential tissue damage so that a person can experience pain. So that during the postoperative period nurses play a very important role in trying to meet the needs of the patient's sense of security and comfort. Pain management can be done with non-pharmacology, including giving aromatherapy using lemon aromatherapy, which aims to reduce pain. Methodology: The purpose of this study was to determine the effect of giving lemon aromatherapy to reducing the pain scale in postoperative BPH patients. The type of research design used in this study was a quasy experiment with a pre-test and post-test research design. The objects in this case study were postoperative BPH patients with impaired feelings of safety and comfort. The collection method in this study was through interviewing respondents by explaining the benefits and purposes of giving lemon aromatherapy and if the respondent met the criteria and was willing to become a respondent then filled in informed consent for willingness. Results: The results of the study showed that postoperative BPH patients after being given lemon aromatherapy decreased their pain level from moderate pain to mild pain.

Keywords: BPH, Pain, Aromatherapy Lemon
Impacto do Pilates na qualidade de vida de pacientes com doença renal crônica: uma revisão sistemática
Authors: Soares Lucas Oliveira , Silva Wasly Santana , Rodrigues Mortari Beatriz Rodrigues , Falleiros Adriana Malavasi , Cordeiro André Luis Lisboa
Published: February 2024

Introdução: A evolução da Doença Renal Crônica (DRC) é silenciosa e assintomática, o que dificulta o diagnóstico e tratamento na fase inicial. Pacientes com DRC apresentam perda de massa muscular, diminuição da capacidade funcional e qualidade de vida (QV). Objetivo: Revisar os efeitos do Método Pilates na QV de pacientes com DRC. Métodos: Trata-se de uma revisão sistemática realizada de acordo com o PRISMA. A busca foi realizada em dezembro de 2022 nas seguintes bases de dados Google Acadêmico, Scielo, Lilacs, CINAHL, Pubmed, PEDro, Web of science e o Cochrane Central Register of Systematic Review. Para execução da busca literária foi utilizada a estratégia PICOT, e a população estudada foi paciente com DRC, a intervenção foi o treinamento com o método Pilates, comparado com pacientes que não realizaram o treinamento ou qualquer outra intervenção, o desfecho avaliado foi QV e incluímos apenas ensaios clínicos controlados e randomizados. Resultados: Foram encontrados 3.287 artigos, dos quais 3 foram considerados elegíveis para a nossa revisão sistemática. Devido a heterogeneidade metodológica, não foi possível realizar meta-análise. Todos os trabalhos incluídos mostraram benefícios significativos da prática do Pilates na QV de pacientes com DRC. Conclusão: Nossos resultados apontam que a prática de exercício físico com o método Pilates pode favorecer a melhora da QV em indivíduos com DRC.
B-cell precursor acute lymphoblastic leukemia elicits an interferon-α/βresponse in bone marrow-derived mesenchymal stroma
Authors: Smeets Mandy W. E. , Steeghs Elisabeth M. P. , Orsel Jan , Stalpers Femke , Vermeeren Myrthe M. P. , Veltman Christina H. J. , Slenders Lotte , Nierkens Stefan , Van de Ven Cesca , Den Boer Monique L.
Published: February 2024

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) can hijack the normal bone marrow microenvironment to create a leukemic niche which facilitates blast cell survival and promotes drug resistance. Bone marrow-derived mesenchymal stromal cells (MSCs) mimic this protective environment in ex vivo co-cultures with leukemic cells obtained from children with newly diagnosed BCP-ALL. We examined the potential mechanisms of this protection by RNA sequencing of flowsorted MSCs after co-culture with BCP-ALL cells. Leukemic cells induced an interferon (IFN)-related gene signature in MSCs, which was partially dependent on direct cell-cell signaling. The signature was selectively induced by BCP-ALL cells, most profoundly by ETV6-RUNX1 positive ALL cells, as coculture of MSCs with healthy immune cells did not provoke a similar IFN signature. Leukemic cells and MSCs both secreted IFNα and IFNβ, but no IFNγ. In line, the IFN-gene signature was sensitive to blockade of IFNα/β signaling, but less to that of IFNγ. The viability of leukemic cells and level of resistance to three chemotherapeutic agents was not affected by interference with IFN signaling using selective IFNα/β inhibitors or silencing of IFN-related genes. Taken together, our data suggest that the leukemia-induced expression of IFNα/β-related genes by MSCs does not support survival of BCPALL cells but may serve a different role in the pathobiology of BCP-ALL.
Method of controlling the volume of combustion products at different boiler loads
Authors: Kryvda V , Brunetkin O , Beglov K , Markolenko T , Lutsenko I
Published: February 2024

Purpose. Development of a method for controlling the volume of combustion products at different load of boiler equipment. Achieving the objective may allow controlling the flue gas temperature and, consequently, the efficiency to increase it. Methodology. Control of the flue gas volume value on the basis of determining the appropriate composition of the fuel gas mixture. Findings. The effect of flue gas temperature increase at use of fuel gases of lower calorific value and increase in ballast gases quantity is revealed. The latter can be the air used as an oxidising agent at its considerable excess. The mechanism of such an effect due to the increase in the quantity and velocity of flue gases is suggested. A parameter determining the volume of flue gases produced per unit calorific value of various fuel gases is proposed. On the basis of this parameter the method for calculating the composition of the mixture of different gases to ensure the constancy of the flue gas volume at variable load is proposed Originality. On the example of the results of verification thermal calculation the change in flue gas temperature and efficiency value is considered. The non-standard character of their change is revealed. In contrast to the case of using fuel gas of constant composition with increasing load, the temperature of flue gases remained close to constant, and the value of efficiency increased. Practical value. The obtained results indicate the possibility of controlling the flue gas temperature and boiler efficiency at a given load. This allows one, unlike the case of using fuel gas of constant composition, to increase the efficiency exactly at maximum load avoiding getting into the condensate mode at minimum load. There is a possibility to save fossil gas and, consequently, to reduce the greenhouse share in CO2 emissions.
Coexistence of Sickle Cell Thalassaemia with Overlapping Syndrome: A Case Report of Systemic Lupus Erythematosus and Autoimmune Hepatitis
Authors: Sawlani Anjlee , Masood Rida , Kumar Jai , Saahil Kartaar
Published: February 2024

This case report highlights a rare and unique occurrence: the simultaneous presence of sickle cell thalassaemia and overlapping syndrome, which involves systemic lupus erythematosus and autoimmune hepatitis. The coexistence of sickle cell disease with overlapping syndrome is exceptionally rare, with only a few documented cases in the literature, one of which involves sickle cell β-thalassaemia. Significantly, this case enhances understanding of the intricate relationship among these conditions, and offers valuable perspectives on how to clinically manage them. The authors present the case of a young male in his early 20s, who presented with haemolytic anaemia, jaundice, joint pain, and hepatomegaly. Extensive laboratory investigations, including serological markers, haemoglobin electrophoresis, and liver function tests, confirmed the coexistence of sickle cell thalassaemia, systemic lupus erythematosus, and autoimmune hepatitis. The treatment included O2 therapy, hydration, hydroxyurea, and antibiotics. After 4–5 days, the patient showed improvement, and at discharge, hydroxyurea and folic acid were continued. Significantly, considering the complex medical history of the patient, a decision was made to include a carefully considered, low-dose steroid regimen. The choice of a maintenance dose over an induction therapy was specifically made to mitigate potential complications, particularly the risk of vaso-occlusive crises in patients with sickle cell disease. This case report contributes to the understanding of concurrent manifestation of these complex conditions, and emphasises the importance of a comprehensive approach, early diagnosis, and timely management, to optimise patient outcomes in such intricate overlapping syndromes.
Examination of Complementary Treatment Use of Individuals with Interstitial Cystitis: Descriptive Study
Authors: Culha Yeliz , Seyhan Ak Ezgi , Culha Mehmet Gokhan
Published: February 2024

Objective: The aim of this study was to examine the use of complementary therapy in individuals with interstitial cystitis. Material and Methods: This study, which was carried out in a descriptive research design, was carried out with 80 female patients over 18 years of age with interstitial cystitis, who applied to the Urology Outpatient Clinic of a city hospital in Istanbul between January and July 2023. The data were collected by face-to-face (onsite) interview method using a form prepared by the researchers in line with the literature to determine the socio-demographic characteristics of the patients and their use of complementary therapy. Data were analyzed using SPSS 22 statistical software for Windows. Results are reported as mean ± SD. Ethics committee and institutional permission were obtained before starting the study. Results: When the characteristics of the individuals included in the study were examined; The mean age was 42.80±10.68 years, 60% did not have a chronic disease, 65% used any complementary treatment method, 43.2% used herbal treatment method, 50% did not receive complementary treatment. 55% received this information from the physician, 50% used complementary therapy to reduce their pain, 61.5% did not experience any side effects after using complementary therapy, 80.8% believed that complementary therapy was effective. It was determined that 53.8% of them did not share the complementary treatment methods they used with the physician or nurse. Conclusion: It was seen that the majority of individuals with interstitial cystitis used any complementary treatment, half of them did not get information before using the treatment, and more than half did not share the complementary treatment methods they used with the physician or nurse.
Urogenital Complications that Decrease Quality of Life in Transgender Surgery
Authors: Bayraktar Zeki
Published: February 2024

Gender reassignment surgeries are performed not to treat a congenital or anatomical anomaly, but to treat the psychological problems of transsexuals. In fact, there is no definitive evidence showing that psychological problems in transsexuals are cured by hormonal and/or surgical treatments for gender reassignment. On the contrary, there is evidence that these psychological problems persist after medical and surgical interventions, and even increase in some transsexuals, and a new form of body dysphoria occurs in a quarter of cases. Psychological problems in transgender people are not cured by surgery, and additional surgery-related complications develop in three-quarters of the cases. The vast majority of these are urogenital complications, and more than half require reoperations. However, in a significant proportion of cases, the outcome is unsuccessful and these urogenital complications significantly reduce the quality of life of transsexuals. Data also show that the life expectancy of transsexuals who undergo surgery is shortened by an average of 25-28 years due to psychological problems, suicides, surgical complications, reoperations and diseases related to hormone use. These results have led to an increase in the number of detransitioners who regret their medical and surgical transition and want to return in recent years, and have increased ethical debates on this issue. In this article, urogenital complications that develop after transgender surgery, which reduce the quality of life and possibly play a role in regrets are summarized.
MODEL SEIAR PENYEBARAN PENYAKIT RABIES PADA MANUSIA
Authors: Hasanah Dian , Sani Asrul , Kabil Djafar Muhammad , Cahyono Edi , La Pimpi
Published: February 2024

Rabies adalah infeksi virus akut yang menyerang sistem saraf pusat dan umumnya diderita oleh hewan berdarah panas dan manusia serta dapat menular. Virus rabies ditularkan kepada manusia melalui gigitan hewan penular rabies seperti anjing, kucing, dan kera. Tujuan dari penelitian ini adalah menentukkan model SEIAR penyebaran penyakit rabies pada manusia dan perilaku selesaiannya. Pembentukkan model diawali dengan membuat diagram alur penyebaran penyakit rabies pada manusia dengan model SEIAR. Hasilnya diperoleh dua titik kesetimbangan yaitu titik kesetimbangan bebas penyakit dan titik kesetimbangan endemik. Analisis kestabilan titik kesetimbangan bebas penyakit menggunakan linearisasi disekitar titik kesetimbangan. Hasilnya, titik kesetimbangan bebas penyakit stabil asimtotik jika bilangan reproduksi dasar kurang dari satu, artinya penyakit akan menghilang setelah jangka waktu tertentu. Simulasi numerik model untuk penyakit rabies yang dilakukan sejalan dengan analisis perilaku model.
Pengembangan Aplikasi Interaktif Perhitungan Permutasi dan Kombinasi Menggunakan Bahasa Python dalam Program Studi Ilmu Komputer
Authors: Muslim Muhammad Andika , Setiawan Abdi , Putri Alsya Adelia , Lazuardiansyah Sultan , Wagiman Dede Yusuf , Syafira Neltriana , Simorangkir Risna , Siagian Ramayani , Indra Zulfahmi
Published: February 2024

Penggunaan bahasa pemrograman Python dalam pengembangan aplikasi perhitungan permutasi dan kombinasi menawarkan pendekatan yang efektif dalam memfasilitasi pemahaman dan pengaplikasian konsep matematika dalam program studi Ilmu Komputer. Dalam penelitian ini, kami menggabungkan keunggulan Python sebagai bahasa pemrograman yang sederhana dan mudah dipahami dengan pembuatan aplikasi berbasis antarmuka pengguna (GUI) yang interaktif. Aplikasi ini dirancang untuk memberikan pengalaman belajar yang menarik, memudahkan pengguna dalam memasukkan nilai dan melihat hasil perhitungan, serta memberikan visualisasi langkah-langkah perhitungan secara grafis.

Metode pengembangan aplikasi didasarkan pada pendekatan interaktif yang menggabungkan pemrograman Python dengan pemahaman konsep matematika permutasi dan kombinasi. Aplikasi ini memungkinkan pengguna untuk memasukkan nilai-nilai n dan r, dan secara otomatis menghitung hasil permutasi dan kombinasi. Visualisasi grafis memungkinkan pengguna untuk melihat langkah-langkah perhitungan secara terperinci, sehingga memperkuat pemahaman konsep matematika yang mendasarinya.

Melalui pengujian dan evaluasi, aplikasi ini telah diuji oleh mahasiswa Program Studi Ilmu Komputer dalam lingkungan pembelajaran. Hasilnya menunjukkan bahwa penggunaan aplikasi ini secara signifikan meningkatkan pemahaman konsep permutasi dan kombinasi, serta memfasilitasi pengaplikasian konsep tersebut dalam konteks pemrograman. Mahasiswa merespons positif terhadap antarmuka yang mudah digunakan, interaksi yang intuitif, dan visualisasi perhitungan yang membantu.

Penelitian ini memberikan kontribusi penting bagi pengembangan kurikulum dalam Program Studi Ilmu Komputer, dengan menggabungkan pemrograman Python dan aplikasi interaktif perhitungan permutasi dan kombinasi. Pendekatan ini memungkinkan mahasiswa untuk mengembangkan pemahaman konsep matematika secara mendalam dan kemampuan pemrograman yang relevan dengan kebutuhan industri. Selain itu, aplikasi ini memperkuat hubungan antara teori dan implementasi praktis, sehingga meningkatkan keterampilan pemecahan masalah komputasional dan pemikiran algoritmik.

 

Kata Kunci: Python, Permutasi, Kombinasi, Aplikasi Interaktif, GUI, Program Studi Ilmu Komputer.
Instagram sebagai Media Informasi Digital Perpustakaan Universitas Pembangunan Nasional “Veteran” Jakarta
Authors: Sinaga Saidun , Muqsith Munadhil Abdul , Ayuningtyas Fitria
Published: February 2024

Perkembangan teknologi informasi memungkinkan perpustakaan untuk meningkatkan efektivitas dan efisiensi layanan kepada pemustaka dengan memanfaatkan media sosial sebagai alat komunikasi. Perpustakaan UPNVJ memilih Instagram sebagai platform komunikasi karena popularitasnya dan kesesuaian fitur dengan kebutuhan. Tujuan penelitian ini adalah untuk menganalisis strategi yang diterapkan oleh Perpustakaan UPNVJ dalam memanfaatkan Instagram sebagai media komunikasi digital guna meningkatkan layanan kepada pemustaka. Penelitian ini menggunakan pendekatan deskriptif kualitatif untuk menggali strategi Perpustakaan UPNVJ menggunakan Instagram. Hasil penelitian menunjukkan bahwa Perpustakaan UPNVJ menggunakan Instagram sebagai media komunikasi dengan menerapkan empat pilar strategi media sosial, yaitu komunikasi, kolaborasi, edukasi, dan hiburan saat memberikan informasi melalui konten. Selain itu, Perpustakaan UPNVJ menerapkan strategi komunikasi media sosial yang baik dengan memperhatikan aspek penting seperti caption, hashtag, story, highlight, direct message, comment, dan like. Faktor keberhasilan yang lain adalah terkait perencanaan konten. Meskipun demikian, penelitian ini menemukan beberapa kendala, yakni kekurangan staf, jumlah pengikut civitas masih sedikit, kesulitan menentukan tema dan membuat caption. Untuk mengatasi hal ini, penelitian merekomendasikan beberapa solusi, yakni perekrutan staf, pembentukan dan pelatihan tim, promosi dan sosialisasi, dan melakukan riset terhadap akun Instagram perpustakaan lain agar mendapat inspirasi, referensi tentang tema dan yang menarik dan relevan.
TRANSFORMING LEARNING EXPERIENCES IN ART AND DESIGN APPRECIATION: A RESEARCH ON E-LEARNING DESIGN AND DEVELOPMENT
Authors: Devanny Gumulya
Published: February 2024

The paper focuses on the design and development of an e-learning course in art and design appreciation. Using the ADDIE model, the study explores the integration of the See Think Wonder approach in the e-learning context. The research aims to enhance learners' engagement, understanding, and appreciation of art and design. The study consists of analysis, design, development, implementation, and evaluation of art and design appreciation e-learning. The findings indicate that the See Think Wonder approach positively impacts the e-learning environment by increasing learner engagement, critical thinking skills, and emotional connection to artworks. The approach facilitates active participation, critical discussions, and improved observation and interpretation of artworks. The e-learning platform offers flexibility and accessibility, enabling learners to study at their own pace. Multimedia elements and interactive activities enhance the learning experience. Evaluation results support the effectiveness of the course, with learners recognizing the value of the See Think Wonder approach in enhancing art and design appreciation. It improves their confidence in analyzing artworks and deepens their understanding of artistic elements and principles. The research contributes to the field of art and design education by highlighting the potential of e-learning in transforming learning experiences. It provides insights for educators and instructional designers seeking to enhance art and design education through digital platforms.
EVALUATING GENERATIVE ARTIFICIAL INTELLIGENCE AND INTERNET SEARCHES IN FOREIGN LANGUAGE GRAMMAR LEARNING: EXAMINING THE ROLE OF EXPERTS THROUGH A STUDY ON VOCABULARY BEGINNING WITH “MER-” IN MALAY
Authors: Murata Yumie
Published: February 2024

This study aimed to clarify the usefulness and limitations of generative artificial intelligence (AI) and online information in the self-study of foreign languages, and to reassess the domain of roles that humans, such as language teachers and experts, should perform. As a learner of Malay, the author attempted to pursue this objective by seeking solutions to grammar-related questions that arose during the process of learning Malay without directly asking teachers or specialists, instead posing questions to generative AI or conducting Internet searches.

The author first pursued the question of using the form "mer-" as a prefix-like element in Malay. The author attempted to resolve this question by applying it to generative AI, including ChatGPT, and by conducting an Internet search. It transpired that the generative AI could not distinguish between prefixes and other elements, and thus failed to resolve the question. Next, through an Internet search and reviewing literature, although no discussions on "mer-" were found in Japan, the following three positions regarding "mer-" were observed in Malaysia: (1) the prefix "mer-" does not exist at all, (2) "mer-" used to be a prefix in the past but was no longer considered as such, and (3) it should be "mar-" instead of "mer-." However, it was not possible to obtain information on whether there possibly were other positions, or if one of these positions had been conclusively proven to be correct. Translations by ChatGPT proved to be useful for understanding literature written in Malay. Internet searches were effective in identifying the relevant literature, even with small search terms. Language teachers and experts are needed for answering to learner’s grammar-related questions. They would also contribute to the development of specialized AI capable of answering grammar-related questions, enabling AI to fulfill this role for learners in the future. Language teachers and experts can then focus on researching other unresolved issues.