bluuebunny/crossref_metadata_2025 huggingface dataset:
HEMŞİRELİK ÖĞRENCİLERİNİN DİYABET VE İNSÜLİN UYGULAMALARINA İLİŞKİN BİLGİ DÜZEYLERİNİN BELİRLENMESİ
Authors: YILDIRIM TOGLUK Şeyma , KAVURMACI Mehtap
Published: March 2021

Amaç: Hemşirelik Fakültesi öğrencilerinin diyabet ve insülin uygulamalarına ilişkin bilgi düzeylerini incelemektir. Yöntem: Tanımlayıcı türdeki araştırma, bir devlet üniversitesinin Hemşirelik Fakültesi’nde 2019-2020 eğitim/öğretim yılında öğrenim gören 2. , 3. ve 4.sınıf öğrencileri ile yapılmıştır. Evrenin tümünün örnekleme alınması hedeflendiğinden herhangi bir örnekleme yöntemi kullanılmamış ve örnekleme araştırmaya katılmayı kabul eden 649 öğrenci alınmıştır. Araştırma verilerinin toplanmasında öğrencilerin tanıtıcı özelliklerini belirlemeye yönelik soru formu ve Diyabet ve İnsülin Uygulamalarına İlişkin Bilgi Düzeyini Belirleme Formu kullanılmıştır. Araştırmadan elde edilen veriler SPSS 22 paket programında analiz edilmiştir. İstatistiksel analizde tanımlayıcı testler, t testi, Anova testi, Kruskal Walls testi ve Mann-Whitney U testleri kullanılmıştır.Bulgular: Araştırmaya katılan öğrencilerin yaş ortalaması 21.31±1.58 olarak saptanmıştır. Öğrencilerin %76.9’u kızdır. Araştırmaya katılan öğrencilerin %76.1’i Anadolu Lisesi mezunudur, %34.1’i 2. ve 3. sınıfta okumaktadır ve %40.7’sinin akademik başarı ortalaması orta düzeydedir. Öğrencilerin Diyabet ve İnsülin Uygulamalarına İlişkin Bilgi Düzeyini Belirleme Formundan aldıkları puan 17.74±2.48 olarak saptanmıştır. Öğrencilerin en yüksek puanı madde 11, madde 7, madde 12 ve madde 1’den alırken, en düşük puanı madde 14 ve madde 18’den almıştır. Sonuç: Araştırma sonucunda hemşirelik öğrencilerinin diyabet ve İnsülin uygulamalarına ilişkin bilgi düzeyi genel puan ortalamasının iyi düzeyde olduğu ve öğrencilerin bazı tanıtıcı özelliklerden etkilendiği saptanmıştır.
Preparation of Village Budgets as the Implementation of Good Governance of Village Government
Authors:   Study Program of Business Administration, Sekolah Tinggi Ilmu Sosial dan Politik (STISPOL) Wira Bhakti Denpasar, Indonesia, Sugiartana I Wayan
Published: March 2021

The purpose of this study is to determine the implementation of Law of the Republic of Indonesia number 14 of 2008 in the preparation of village budgets to achieve good governance in the Village Government X in terms of the dimensions of village budget design, village budget study, ratification and enactment of village budgets, stipulation of budget implementation regulations village. This research is a descriptive study, with a population of 5,575 people, and a sample of 373 people was determined using the stratified random sampling method. The questionnaire was used for data collection and then analysed using descriptive analysis techniques. The research shows that the Village Government X in terms of the village budget drafting is in the agreed category. Judging from the discussion of the village budget, it is in the agreed category. Judging from the approval and promulgation of the village budget, it is in the agreed category. Judging from the implementation regulations of the village budget, it is in the very agree category. So it can be concluded that the Government of Village X Regency Y is able to implement Law Number 14 Year 2008 in preparing the village budget properly.
A CONCEPTUAL STUDY ON EFFECT OF NAGARADYA CHURNA IN GRAHANI ROGA
Authors:   MD 2ND Year, PG Department of Kaya Chikitsa, Rishikul Campus,Uttarakhand Ayurved University, Haridwar, Uttarakhand, KUMAR PAWAN
Published: March 2021

Grahani Roga is one of the leading disorders of Annavaha Srotasa. It is mentioned in classics that root cause of all the diseases is Mandagni, which occurs due to improper following of dietary regimen and daily routine. The main site of Agni is Grahani the part of intestine between Amashaya & Pakwashaya. Therefore disturbance in function of Agni leads the disorder known as Grahani Roga. The symptoms of Grahani Roga are similar to mal-absorption syndrome, coeliac disease, tropical sprue, and irritable bowel disease as described in modern medical science. Grahani Roga is treated by Shamana and Samsodhana Chikitsa. Deepana Pachana drugs are useful to enhance the potency of Agni. Now the need of Ayurvedic medicine arises to fill this lacuna. there are number of preparation described in Ayurveda text and Nagaradya Churna in one among them and it has wonderful propertiese that helps in curing Grahani Roga . Thus Ayurvedic treatment is more effective in managing the patients of Grahani Roga by breaking the pathogenesis due to Deepana-Pachana, Grahi, and Srotoshodhaka properties.
Vaccine Induced Prothrombotic Immune Thrombocytopenia (VIPIT) Following AstraZeneca COVID-19 Vaccination
Authors: Pai Menaka , Grill Allan , Ivers Noah , Maltsev Antonina , Miller Katherine J. , Razak Fahad , Schull Michael , Schwartz Brian , Stall Nathan M. , Steiner Robert , Wilson Sarah , Niel Zax Ullanda , Juni Peter , Morris Andrew M.
Published: March 2021

This Science Brief provides information for health care professionals about Vaccine Induced Prothrombotic Immune Thrombocytopenia (VIPIT), a rare adverse event following the AstraZeneca vaccine. This brief describes the pathophysiology, presentation, diagnostic work-up and treatment of VIPIT. Figure 1 presents a decision tree for diagnosis and rule out of VIPIT.
PREVENCIÓN DE LA VIOLENCIA DE GÉNERO DESDE LA EDUCACIÓN SUPERIOR
Authors: Peña-Briceño Daniel
Published: March 2021

La violencia de género es un problema de salud pública, que afecta a la sociedad ecuatoriana en todos sus niveles, siendo el ámbito educativo universitario igualmente afectado por esta conducta machista. Donde el sector femenino como sujeto y objeto de agresión es la principal víctima de esta acción. El presente estudio tuvo como fin establecer un plan de acciones para la prevención de la violencia de género desde la perspectiva de la educación superior. Para su logro se utilizó una metodología de investigación fundamentada en el paradigma positivista, con un enfoque cuantitativo bajo la modalidad de estudio Proyecto Factible y de nivel Descriptivo. La técnica de recolección de datos fue el fichaje y como instrumento la ficha de contenido. La técnica de análisis de los datos fue el análisis de contenido. Entre las conclusiones, se estableció la importancia de empoderar a la mujer sobre sus derechos y de la manera para evitar la violencia de género dentro del campus universitario y en la comunidad en general. Motivado a que las mujeres no hacen valer los derechos que poseen para lograr una vida libre de violencia.
MATERIALES EDUCATIVOS PARA LA PREVENCIÓN DE LA VIOLENCIA DE GÉNERO EN LA EDUCACIÓN SUPERIOR
Authors: Guerrero-Vera Carmen Mariuxi
Published: March 2021

El aumento de los casos de la violencia de género en la sociedad ecuatoriana, de los cuales no escapa la universidad, ha traído como consecuencia una violación sistemática a los derechos de la mujer ecuatoriana. Es por ello, que la presente investigación tiene como fin el Determinar los Materiales Educativos como Herramienta para la Prevención de la Violencia de Género en la Educación Superior. Esta investigación se ubicó en el paradigma positivista, con un enfoque cuantitativo, de tipo de campo con un nivel descriptivo. La población de estudio integrada por 30 Docentes y 230 estudiantes del primer año de la escuela de derecho, de la facultad de derecho de la Universidad Metropolitana UMET. La muestra estuvo constituida por 10 Docentes y 80 estudiantes. Como técnica de recolección de datos se utilizó la encuesta y como instrumento el cuestionario con respuestas dicotómicas. Entre los resultados se obtuvo que, el 89% de los consultados conoce lo que es la violencia de género, así como el 65% de los consultados manifestó que no han oído de casos de violencia de género en la universidad. Se concluyó que existe la necesidad de la implementación de estrategias que, de alguna manera permitan prevenir tal situación. Para ello, los Materiales Educativos como Herramienta para la Prevención de la violencia de género desde la Educación Superior resulta una estrategia relevante a tomar en consideración
Workplace Skills and Teacher Competency from Culinary Arts Students’ Perspectives
Authors: Mohamed Hanis , Mohd Puad Mohd Hazwan , Mat Rashid Abdullah , Jamaluddin Rahimah
Published: March 2021

Workplace skills are essential skills needed by graduates today to fulfill the demands of employers. Employers in the hospitality industry are looking for well-prepared Culinary Arts graduates that possess adequate training and are equipped with workplace skills to fill up positions in the job market. Apart from skills, teacher competency impacts the acquisition of knowledge and workplace skills among Culinary Arts students and contributes to the issue of unemployment. This study aims to differentiate workplace skills and teacher competency based on gender, socio-economic status, as well as academic and vocational achievements of Culinary Arts students. Furthermore, the relationship between workplace skills and teacher competency is assessed. This correlational study was conducted at Malaysian vocational colleges offering 2-year Culinary Arts programs involving 198 final year students. A 5-point Likert-scale questionnaire was used for data collection. The findings demonstrated that the students’ workplace skills and perception of teacher competency were at a moderate level. No significant differences were noted based on gender, socioeconomic status, as well as academic and vocational achievements. Teacher competency and workplace skills were correlated moderately and positively. This study provides a basis and serves as a reference to the Technical and Vocational Education and Training practitioners to design a curriculum for vocational college students in improving the acquisition of students’ workplace skills. Teachers are recommended to play an active role in efficiently integrating workplace skills in the learning process to enhance their competencies.
Consumer Perceived Value of Organic Vegetables: Does Ethnic Group Matter?
Authors: Hee Ong Choon , Lin Tan Koh
Published: March 2021

This study examined the role of ethnic groups on factors influencing the perceived value of organic vegetables among consumers in Malaysia. An online survey questionnaire collected 385 responses. Partial least squares-structural equation modeling (PLS-SEM) was used to assess the validity, reliability, hypothesis testing, importance-performance map analysis (IPMA) of the study constructs. Partial least squares-multi-group analysis (PLS-MGA) was employed to examine whether there are significant differences among various ethnic groups. The findings revealed that food safety concerns, health concerns, and trust in organic food claim significantly influenced the consumer perceived value of organic vegetables. This study offers new findings regarding the role of ethnic groups in explaining significant differences among consumers toward the perceived value of organic vegetables. It also provides essential information to the ministry of agriculture, organic farmers, dealers, and retailers in developing marketing strategies and expansion plans to achieve higher household expenditures on organic vegetables.
Consumer Adoption of Alipay in Malaysia: The Mediation Effect of Perceived Ease of Use and Perceived Usefulness
Authors: Lui Tze Kiat , Zainuldin Mohd Haniff , Yii Kwang-Jing , Lau Lin-Sea , Go You-How
Published: March 2021

Despite a growing trend in m-wallet services in Malaysia, the actual level of usage is considered low among all of the non-cash payment methods. The Malaysian government has taken a serious initiative in spurring the use of m-wallets by providing a one-off RM30 incentive to all eligible Malaysians. As such, it is important to understand the motivations behind m-wallet usage by examining Alipay, which is favoured in the international, as well as Malaysian markets. This research investigates the effects of mobile payment knowledge, personal innovativeness, self-efficacy, convenience, and compatibility on the actual adoption of Alipay in Malaysia with perceived ease of use and perceived usefulness, as the mediators. Using importance-performance map analysis (IPMA) and Variance Accounted For (VAF), based on Partial Least Squares - Structural Equation Modelling (PLS-SEM) on 260 respondents, it was discovered that compatibility and perceived usefulness demonstrated high importance in improving the performance of Alipay adoption. The results also showed a direct effect between compatibility and mobile payment knowledge. Additionally, perceived usefulness was shown to be an essential mediator in influencing the impact of compatibility and convenience on the actual adoption of Alipay. This study has produced essential policy recommendations for both mobile wallet providers and policymakers on how to further promote the adoption of mobile wallets in Malaysia.
Which Consumers are Least Likely to Have a Balanced Diet in Japan?
Authors: Ishida Akira , Ishida Emiko
Published: March 2021

There have been only a few large-scale nationwide studies regarding the frequency of eating a balanced diet consisting of staple food, the main dish, and side dishes in Japan. Therefore, this study aimed to clarify factors affecting the frequency of eating a balanced meal that consists of staple food, the main dish, and side dishes twice a day. We analyzed the secondary data of 13,772 responses from the 7-year pooled cross-sectional data of the nationwide Surveys of Attitudes toward Shokuiku (Food and Nutrition Education) by the Cabinet Office and the Ministry of Agriculture, Forestry and Fisheries of Japan. Ordered logit regression was used to find factors affecting the frequency of having a balanced diet. Our estimation results suggested that gender, age, cohabitation, eating meals with family, subjective economic status, and residential area could be factors affecting the probability of having balanced meals every day. In conclusion, single men in their 20s-50s, single men in their 80s, older male adults living but not eating together with family, single women in their 20s-30s, and individuals with low economic status were identified as high-risk groups who do not have a balanced diet in Japan. Moreover, we found that the government health promotion program called Kenko Nippon 2013 (Health Japan 21, the second term) did not improve the dietary behavior of the consumer in Japan.
Transnational Identity in Unaccustomed Earth: A Study of Jhumpa Lahiri’s and Chitra Banerjee Divakaruni’s Short Fictions
Authors: Hasnan Aisyah , Mohd Pakri Mohamad Rashidi
Published: March 2021

This paper intends to examine transnational identity of first- and second-generation Indian diasporic and/or transnational subjects through the portrayal of protagonists in Jhumpa Lahiri’s and Chitra Banerjee Divakaruni’s short fictions: “Unaccustomed Earth” and “Hell-heaven” (2008), “Clothes” and “Silver Pavements and Golden Roofs (1995)”. Theories of transnationalism, identity and transnational identity were used to scrutinise the ways those fictional characters define themselves as well as the ways they negotiate homeland and the ‘unaccustomed earth’. This paper also discovers opportunities, and difficulties faced by first- and second-generation Indian immigrants, and the differences between the impacts of crossing national boundaries towards both communities. This study used textual analysis of selected narratives for an understanding of transnational identity in literature, and how Indian diasporic or transnational subjects made sense of their roots and routes when those fictional characters were trapped in between their Indian roots, and the need to make sense of unaccustomed earth.
Malaysian Youth eHealth Literacy via Healthcare Websites: A Study on Factors Forming Sexual and Reproductive Health Information-seeking Intention
Authors: George Andrew Jason , Waheed Moniza
Published: March 2021

Extensive research has been carried out to study the relationship between Malaysian youth and their perceptions of sexual and reproductive health (SRH); ranging from knowledge and awareness levels to lifestyle choices. However, there is insufficient information on youth e-health literacy levels on the subject matter. Therefore, this study examines the factors that influence youth intention towards using healthcare websites to search for SRH information. This study is guided by the Theory of Reasoned Action (TRA) which suggests that the best indicator of behaviour is intention, which is formed by attitude and subjective norms. Participants for the study were 400 youth (from 18 – 40 years of age) based in the Klang Valley area. Data was collected through a self-administered questionnaire where the research instruments were adopted from the TRA framework, namely: Attitude, Subjective Norms, and Intention. Overall, the findings showed that youth who had positive attitudes and adequate social support/pressure towards using healthcare websites to find SRH information were likely to have a high intention to do so. One crucial finding in the context of this study is how subjective norms are a stronger predictor of SRH information-seeking intention compared to attitude. This finding here can add a new dimension to how the TRA framework is utilised, especially in studies revolving around Asian youth intentions and behaviours. Ministries, NGOs, and private institutions that advocate better SRH practices in Malaysia should leverage the influence of new media to improve health literacy levels among youth.
Determinants of Financial Liberalization in SAARC Region
Authors: Hashmi Syed Danial , Naz Iram , Mehmood Farrukh , Farooqi Mattiullah
Published: March 2021

Financial liberalization is the face of financial reforms around the world. This study examines the determinants of financial liberalization in SAARC (South Asian Association for Regional Cooperation) countries. The study considers both political and economic factors as possible determinants of financial liberalization. Data from five countries of the South Asian region (Bangladesh, India, Nepal, Pakistan, and Sri Lanka) over a time span of 48 years i.e. 1970 to 2018 had been analyzed. We selected 1970 as a start point of data as liberalization policies were theoretically advocated for and practically started implementing in the ’70s. The result of panel data estimation shows that among economic factors trade openness, foreign reserves, economic development (GDP growth), and recession predict financial liberalization in the SAARC region. Further, political stability and level of democracy are important political factors in predicting financial liberalization in the region. The country-specific analysis shows some variation from the overall region and is reported in the results section. We also tested for the likelihood of dynamic modeling. However, the result of Arellano and Bond estimation shows that static modeling is appropriate in our context and validates the robustness of our initial estimates. Our study gives useful insights to the policymakers who aim to liberalize the financial markets.
Economic Efficiency of Stingless Bee Farms in Peninsular Malaysia Estimated by Data Envelopment Analysis (DEA)
Authors: Soh Norhidayah Che , Samsuddin Nur Syahirah , Ismail Mohd Mansor
Published: March 2021

The commercial stingless beekeeping industry has good economic growth potential in Malaysia, which is a tropical country rich in flora that serves as food sources for stingless bees. Local consumption of honey is increasing and its production locally can be raised to meet the demand by sustainable stingless beekeeping. An important indicator that measures the success of the industry is the economic efficiency of the farm. This study hence examined the cost efficiency (CE), technical efficiency (TE), and allocative efficiency (AE) of commercial stingless beekeeping farms in the East Coast and Northern regions of Peninsular Malaysia using Cost Data Envelopment Analysis (DEA) under the assumption of Constant Return to Scale (CRS). Interviews with 47 respondents in the East Coast region and 28 respondents in the Northern region showed that the average CE scores for the two regions were 0.291 and 0.172, respectively. TE for the East Coast region and Northern region were 0.656 and 0.385 while mean AE scores of 0.445 and 0.404 were obtained. Factors that influenced the efficiency of the farms included farmers’ years of schooling and extension officer visits. In conclusion, CE, TE, and AE of commercial stingless bee honey production in Peninsular Malaysia were fairly low, and the determinants responsible for this low efficiency is of concern. Economic efficiency in stingless beekeeping needs to be further elevated to optimise productivity.
Study on the Role of Corporate Culture in Human Resource Management
Authors: Han Xinliang
Published: March 2021

This paper analyzes the role of corporate culture in human resource management, including corporate culture as a guide, corporate culture as an incentive to employees, to employees, corporate culture has the role of attracting and maintaining talent, In human resources training plays a key role, corporate culture has a cohesive role.This paper probes into the effective countermeasures of the role of corporate culture in human resource management, including cultivating the innovative consciousness of talents, selecting personnel by using the core values of enterprises, and guiding employees to carry out career planning by using corporate culture.
Perceived Family Environment and Self-Concept Among Young Adults in Indian Context
Authors: Mishra Ms. Anshika , Bhatt Mrs. Sandhya
Published: March 2021

'Self' can be described in a very extensive manner, but it stays to be exclusively individualistic to a person's existence and experience. Family Environment has been known to influence the Self Concept as it was observed to have a tangible impact, with many roles inclusive in collectivistic cultures such as India. The purpose of the paper was to establish the link between Family Environment and Self Concept in Indian Context among Young Adults. The methodology used for the paper is Qualitative Research on the basis of a survey conducted upon 40 young adults questioning them about Perceived Family Environment and Self Concept. The survey resulted that in the family environment, people when in accordance to family's expectations receive affection, support, expressiveness and other conditions show positive Self Concept. But, the results also established individual components such as hating self in situations of failures, prioritizing expectations of others over own. This proves that all other factors were dependent on expectations of family, reflecting that their Self Concept is interdependent of societal roles and of roles assigned by the family. Our traditional family system (collectivistic culture) and environment, conditions us to create our Self Concept based on the parameters and expectation framework created by the family.
Synergistic effects of ivabradine and metformin in the treatment of concomitant chronic heart failure and diabetes mellitus by regulating the activity of the H19/miR-423-5p/HCN4 axis
Authors: Zhang Fang , Jiang Weijun , Liu Yating , Li Liu , Wang Rui , Li Yang
Published: March 2021

Introduction

In this study, the molecular mechanisms underlying the therapeutic effect of metformin (MET) and ivabradine (IBD) in the treatment of concomitant chronic heart failure (CHF) and diabetes mellitus (DM) were investigated.

Material and methods

Basic and cardiac indexes were measured to study the therapeutic effect of MET and IBD. Real-time PCR, IHC assays, in-silicon analysis, luciferase assays, real-time PCR and Western blot assays were conducted to clarify the molecular mechanisms underlying the interaction between MET and IBD.

Results

MET administration restored the normal values of general/cardiac indexes in CHF rats. The abnormal values of echocardiographic indexes in CHF rats with STZ-induced DM were all corrected by a certain degree after the MET administration. Moreover, the injection of STZ up-regulated the expression of plasma NE/BNP-45, while the IBD administration reduced the levels of NE/BNP-45 in CHF rats. Furthermore, the administration of MET also reduced the NE level in CHF rats, indicating that both MET and IBD can exert a therapeutic effect on CHF rats. Additionally, in-silicon analysis and luciferase assays verified the role of H19 and HCN4 as target genes of miR-423-5p. In fact, the transfection of MET or H19 siRNA1/2 into HL-1 and H9C2 cells down-regulated the levels of H19 and HCN4 while increasing the level of miR-423-5p.

Conclusions

MET reduces H19 expression via inducing methylation of its promoter, and the inhibited H19 expression suppresses HCN4 expression by up-regulating miR-423-5p expression. As a result, the suppressed expression of HCN4 reduces heart rate and exhibits a therapeutic effect in the treatment of concomitant CHF and DM.
H2S alleviates Parkinson-like phenotypes by modulating lncRNA-CasC7/miR-30c/BNIP3L signaling pathway
Authors: Long Ling , Cai Xiaodong , Liao Jinchi , Ma Xiaomeng , Liu Yingying , Huang Yiying , Liu Xu , Chen Xiaohong
Published: March 2021

Introduction

The pathogenesis of Parkinson’s disease (PD) is closely related to mitophagy, a process regulated by miRNAs and long non-coding RNAs (lncRNAs). In this study, we investigated the role of the lncRNA-CasC7/miR-30c/BNIP3L (BCL2 Interacting Protein 3 Like) signaling pathway in PD.

Material and methods

A 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of PD was generated and treated by hydrogen sulfide (H2S) inhalation. The SH-SY5Y cell model of PD was generated by MPP+ and the treatment was NaHS. The open field, rotarod and tail suspension tests were performed to assess motor deficits. TUNEL and immunofluorescence assays were used to evaluate neuronal apoptosis in mice and in SH-SY5Y cell culture. Real-time PCR was performed to measure the expression level of the lncRNA-CasC7, miR-30c and BNIP3L, and western blotting was used to assess the protein levels of CBS, BNIP3L and PINK1. Luciferase assays were conducted to examine the regulatory relationship between miR-30c and lncRNA-CasC7/BNIP3L.

Results

H2S inhalation alleviated the motor disorder and neuronal apoptosis in PD mice, and NaHS treatment inhibited apoptosis in the SH-SY5Y cell culture model of PD. The sulfide compounds also ameliorated the dysregulated expression of CasC7, miR-30c, BNIP3L, and PINK1 in the PD models. Furthermore, miR-30c significantly inhibited the expression of lncRNA-CasC7 and BNIP3L, as assessed with the luciferase assays.

Conclusions

Our findings suggest that the lncRNA-CasC7/miR-30c/BNIP3L mitophagy signaling pathway is involved in the pathogenesis of PD.
AnnexinA7 and CAP1 are associated with regulating tumor cell adhesion molecule expression and biological behavior
Authors: Wang Li , Wang Yang , Liu Zhiyan , Zhou Yixia , Zhang Jun , Tang Jianwu
Published: March 2021

Introduction

To find out the correlations between the effects of down-regulating AnnexinA7 and CAP1 gene on cell adhesion factors and the biological behavior of Hca-p cells cells, and finally infer the relationship between the two genes.

Material and methods

Western blot ,qRT-PCR,immunocytochemistry, CCK8 cell proliferation, flow cytometry, lymph node adhesion and transwell chamber assay testing .

Results

AnnexinA7 and CAP1 were consistent with the regulation of the expression of the adhesion molecules such as FAK, Src, Paxillin and E-cadherin. At the mRNA and protein levels, the expression of FAK, Src and Paxillin were increased with down-regulated AnnexinA7 and CAP1 genes, while E-cadherin was down-regulated in the change of these two genes. And the low expression of AnnexinA7 could affect the expression of CAP1 in mRNA and protein levels. otherwise, the localization of AnnexinA7 and CAP1 in hepatocellular carcinoma cells was also the same. After down-regulating the expression of CAP1, the functions of proliferation, lymph node adhesion and invasion were increased and early apoptotic ability was decreased in Hca-P cells.

Conclusions

AnnexinA7 and CAP1 could control the expression of these adhesion molecules in the same trend. We speculated they may be co-localization. And AnnexinA7 gene may be related to the molecular mechanism of CAP1 gene, which is likely to have a consistent effect on cell adhesion molecules and be closely related to the biological behaviors of Hca-P cells.AnnexinA7 and CAP1 may play an inhibitory role in lymph node metastasis to provide a reliable basis for the early identification of lymphatic metastasis in hepatocellular carcinoma.
Resolución de diagramas de flujo y pseudocódigo por parte de estudiantes de Ciencias de la Computación de la Universidad de Costa Rica
Authors: Villalobos Fernández Luis Andrés , De la Ossa Osegueda Álvaro , Rodríguez-Villagra Odir Antonio , Vergara Heidke Adrián Esteban
Published: March 2021

En este trabajo se ha llevado a cabo un estudio de seguimiento ocular de 20 estudiantes de Ciencias de la Computación de la Universidad de Costa Rica, la mitad de ellos de primer curso y la otra mitad de cuarto. Se les pidió que resolvieran 10 ejercicios de diagramas de flujo y 10 de pseudocódigo. En los alumnos expertos, aproximadamente la mitad de las fijaciones se centran en las áreas de interés más relevantes para la resolución del problema, mientras que, en los novatos, aproximadamente un tercio de las fijaciones se concentran en esas áreas. Al calcular la densidad de fijaciones en las áreas de interés, este patrón es mucho más evidente. En cuanto al rendimiento, se observaron diferencias significativas entre expertos y novatos, mostrando los primeros mejor rendimiento. En lo relativo a la duración de la resolución de los ejercicios, solo se encontraron diferencias significativas entre expertos y novatos al resolver pseudocódigos. En función de los resultados obtenidos se llevan a cabo recomendaciones para los profesores de los cursos de programación y para futuras investigaciones.
Design thinking: un enfoque educativo en el aula de segundas lenguas en la era pos-COVID
Authors: Mena Octavio Manuela
Published: March 2021

Este trabajo ha obtenido un Accésit del Premio Estudios Financieros 2020 en la modalidad de Educación y Nuevas Tecnologías.El nuevo escenario que se abre en las aulas de los centros educativos de nuestro país con la llegada de la era pos-COVID podría suponer la palanca de cambio definitiva para modificar las arcaicas estructuras sobre las que se asienta nuestro sistema educativo actual. En este nuevo contexto hay dos elementos que van a desempeñar un papel crucial: la empatía y la tecnología.El presente trabajo de investigación tiene como objetivo justificar la necesidad de implementar un enfoque como el design thinking (DT) dentro del modelo de enseñanza-aprendizaje en remoto. Asimismo, se presenta una experiencia de innovación educativa para el aula en línea de lengua extranjera con estudiantes de secundaria a fin de fomentar la empatía, la competencia digital y el aprendizaje colaborativo a partir del desarrollo de tareas significativas en remoto.
Ecologías de aprendizaje en educación secundaria: TIC y aprendizaje informal
Authors: Martinenco Rebeca Mariel , Martín Rocío Belén , García Romano Leticia
Published: March 2021

Actualmente se sabe que los estudiantes aprenden en diversos contextos y haciendo un amplio uso de las tecnologías de la información y la comunicación (TIC) (Maina y García, 2016). En el presente trabajo nos proponemos identificar qué aplicaciones, plataformas web, redes sociales y tecnologías digitales utiliza un grupo de estudiantes de educación secundaria mediante un cuestionario autoadministrado. En primer lugar, haremos referencia al concepto de «ecologías de aprendizaje» y a su vinculación con el aprendizaje informal y las TIC. El apartado de «Material y métodos» recoge la caracterización de los participantes y una descripción detallada del instrumento utilizado. Desde un enfoque cualitativo, los resultados se organizan en cuatro categorías. A modo de discusión, planteamos la incidencia de las tecnologías en múltiples aspectos de la vida de los participantes.
Problemática de estudio e investigación de la adicción a las redes sociales online en jóvenes y adolescentes
Authors: Valencia-Ortiz Rubicelia , Cabero-Almenara Julio , Garay Ruiz Urtza , Fernández Robles Bárbara
Published: March 2021

El uso excesivo de las redes sociales puede provocar efectos contraproducentes en los jóvenes: aislamiento social, distorsión entre el mundo real y virtual, falta de atención hacia otras actividades, depresión, ansiedad, problemas de salud y fracaso escolar. Ante esta perspectiva, es importante ofrecer información sobre las redes sociales desde una visión educativa. Con este artículo se pretende analizar el impacto que tienen en los jóvenes y estudiar algunos elementos que hay que controlar desde el ámbito educativo. Para ello, se realizó una revisión bibliográfica por diversas fuentes científicas, empleando un total de 116 publicaciones. Tras el análisis de estas fuentes científicas, se concluyó que las instituciones educativas, los docentes y los padres desempeñan un papel significativo para disminuir los desafíos que aparecen al emplear las redes sociales. Las instituciones educativas y los docentes deben ofrecer medios para desarrollar competencias digitales que permitan a los jóvenes desenvolverse de forma adecuada con ellas. Respecto a los padres, es necesario brindarles información para que guíen a sus hijos en la utilización de estas tecnologías.
Reseña. Gómez Canseco, Luis, Don Juan Enríquez de Zúñiga y su perrita, Huelva, Universidad de Huelva (Biblioteca biográfica del Renacimiento Español), 2020, 139 págs. ISBN: 978-84-18280-18-4
Authors: Navarro Espinosa Natalia
Published: March 2021

RESUMEN:
Reseña del libro de Luis Gómez Canseco, Juan Enríquez de Zúñiga y su perrita.
ABSTRACT:
Review of the book Juan Enríquez de Zúñiga y su perrita, by Luis Gómez Canseco.
Nitrogen Requirement of Italian Rygrass (Lolium multiflorum) : A Review
Authors: SEYDOŞOĞLU Seyithan , KÖKTEN Kağan
Published: March 2021

Nitrogen is an essential nutrient for ryegrass growth and development but excess of it may lead to accumulation of nitrate in plants which may be lethal for ruminants. Irrigation, seed rate, variety, quality, cutting time and frequency, location alittude and fertilizer types are variables in the different articles in this review we selected to see the reaction of Italian rygrass to different nitrogen doses in core. A series of comments were also mentioned in the conclusion part of this article to improve future studies in thes area.
Breve análisis comparativo entre la regulación del Consejo para la Transparencia de Chile y el Consejo de Transparencia y Buen Gobierno de España
Authors: Astudillo Jorge Luis
Published: March 2021

Este trabajo tiene como finalidad ofrecer un sucinto repaso de las principales características estructurales y funcionales del Consejo para la Transparencia chileno y luego contrastarlas con la regulación que hace del Consejo de Transparencia y Buen Gobierno la Ley 19/2013 en España. Lo que se busca es destacar las principales fortalezas y debilidades de la regulación chilena en relación a la normativa contenida en la Ley 19/2013 y con ello establecer algunas bases mínimas que permita abordar ambas legislaciones en forma comparada, procurando destacar los aspectos mejor logrados en cada una de ellas.
Publicidad institucional y pluralismo informativo
Authors: Magallón Rosa Raul
Published: March 2021

Esta investigación analiza el papel en España de la Administración General del Estado a la hora de establecer el reparto de la publicidad institucional así como de las campañas comerciales desde la aprobación de la Ley de Publicidad Institucional de 2005.  Además de los cambios de gobierno, hay escenarios políticos y económicos que también condicionan el desarrollo y ejecución de los planes de publicidad institucional. La caída de la inversión en publicidad institucional ha sido muy importante en términos generales y en todos los medios publicitarios en la última década, menos en Internet, que se ha mantenido mejor.
Por otra parte, entre 2006 y 2018 el presupuesto destinado a campañas comerciales ha aumentado en 10 millones de euros, un 10,42%. Sin embargo, el presupuesto destinado a la comunicación y publicidad institucional se ha reducido un  89,76% y más de 188 millones de euros
¿Se vulneró el Derecho a recibir información durante el primer estado de alarma en la crisis del COVID 19?
Authors: Rodríguez Blanco Victoria
Published: March 2021

Durante el confinamiento de los ciudadanos españoles decretado por el primer estado de alarma de marzo de 2020 la mayoría de los medios de comunicación disponían únicamente de la información oficial que emitía el Gobierno en las ruedas de prensa diarias. Pero los ciudadanos no recibimos información alternativa ni tampoco toda la información relativa a la Covid 19. Después de comparar diferentes medios y la opinión de expertos se concluye que desde el gabinete de comunicación del gobierno se ocultó deliberadamente fotos o imágenes de los fallecidos que se agolpaban en instalaciones previstas ad hoc. No vimos imágenes de los muertos en los hospitales de campaña establecidos para atender a todos los ciudadanos fallecidos. Hubo un silencio informativo gubernamental intencionado con un afán de manipulación política.
Measurement report: Emissions of intermediate-volatility organic compounds from vehicles under real-world driving conditions in an urban tunnel
Authors: Fang Hua , Huang Xiaoqing , Zhang Yanli , Pei Chenglei , Huang Zuzhao , Wang Yujun , Chen Yanning , Yan Jianhong , Zeng Jianqiang , Xiao Shaoxuan , Luo Shilu , Li Sheng , Wang Jun , Zhu Ming , Fu Xuewei , Wu Zhenfeng , Zhang Runqi , Song Wei , Zhang Guohua , Hu Weiwei , Tang Mingjin , Ding Xiang , Bi Xinhui , Wang Xinming
Published: March 2021

Abstract. Intermediate-volatility organic compounds (IVOCs) emitted from vehicles are important precursors to secondary organic aerosols (SOA) in urban areas, yet vehicular emission of IVOCs, particularly from on-road fleets, is poorly understood. Here we initiated a field campaign to collect IVOCs with sorption tubes at both the inlet and the outlet in a busy urban tunnel (>30,000 vehicles per day) in south China for characterizing emissions of IVOCs from on-road vehicles. The average emission factor of IVOCs (EFIVOCs) was measured to be 16.77 ± 0.89 mg km-1 (Average ± 95% C.I.) for diesel and gasoline vehicles in the fleets, and based on linear regression the average EFIVOCs was derived to be 62.79 ± 18.37 mg km-1 for diesel vehicles and 13.95 ± 1.13 mg km-1 for gasoline vehicles. The EFIVOCs for diesel vehicles from this study was comparable to that reported previously for non-road engines without after-treatment facilities, while the EFIVOCs for gasoline vehicles from this study was much higher than that recently tested for a China V gasoline vehicle. IVOCs from the on-road fleets did not show significant correlation with the primary organic aerosol (POA) or total non-methane hydrocarbons (NMHCs) as results from previous chassis dynamometer tests. Estimated SOA production from the vehicular IVOCs and VOCs surpassed the POA by a factor of ~ 2.4, and IVOCs dominated over VOCs in estimated SOA production by a factor of ~ 7, suggesting that controlling IVOCs is of greater importance to modulate traffic-related OA in urban areas. The results demonstrated that although on-road gasoline vehicles have much lower EFIVOCs, they contribute more IVOCs than on-road diesel vehicles due to its dominance in the on-road fleets. However, due to greater diesel than gasoline fuel consumption in China, emission of IVOCs from diesel engines would be much larger than that from gasoline engines, signaling the overwhelming contribution of IVOC emissions by non-road diesel engines in China.
Assessing the dynamics of soil salinity with time-lapse inversion of electromagnetic data guided by hydrological modelling
Authors: Farzamian Mohammad , Autovino Dario , Basile Angelo , De Mascellis Roberto , Dragonetti Giovanna , Monteiro Santos Fernando , Binley Andrew , Coppola Antonio
Published: March 2021

Abstract. Irrigated agriculture is threatened by soil salinity in numerous arid and semi-arid areas of the
world, chiefly caused by the use of highly salinity irrigation water, compounded by excessive
evapotranspiration. Given this threat, efficient field assessment methods are needed to monitor
the dynamics of soil salinity in salt-affected irrigated lands and evaluate the performance of
management strategies. In this study, we report on the results of an irrigation experiment with
the main objective of evaluating time-lapse inversion of electromagnetic induction (EMI) data and
hydrological modelling in field assessment of soil salinity dynamics. Four experimental plots were
established and irrigated 12 times during a 2-month period, with water at four different
salinity levels (1, 4, 8 and 12 dS m−1) using a drip irrigation system. Time-lapse
apparent electrical conductivity (σa) data were collected four times during the
experiment period using the CMD Mini-Explorer. Prior to inversion of time-lapse
σa data, a numerical experiment was performed by 2D simulations of the water
and solute infiltration and redistribution process in synthetic transects, generated by using the
statistical distribution of the hydraulic properties in the study area. These simulations gave
known spatio-temporal distribution of water contents and solute concentrations and thus of bulk
electrical conductivity (σb), which in turn were used to obtain known
structures of apparent electrical conductivity, σa. These synthetic
distributions were used for a preliminary understanding of how the physical context may influence
the EMI-based σa readings carried out in the monitored transects as well as being used to
optimize the smoothing parameter to be used in the inversion of σa
readings. With this prior information at hand, we inverted the time-lapse field
σa data and interpreted the results in terms of concentration distributions
over time. The proposed approach, using preliminary hydrological simulations to understand the
potential role of the variability of the physical system to be monitored by EMI, may actually
allow for a better choice of the inversion parameters and interpretation of EMI readings, thus
increasing the potentiality of using the electromagnetic induction technique for rapid and
non-invasive investigation of spatio-temporal variability in soil salinity over large areas.
Improved machine-learning-based open-water–sea-ice–cloud discrimination over wintertime Antarctic sea ice using MODIS thermal-infrared imagery
Authors: Paul Stephan , Huntemann Marcus
Published: March 2021

Abstract. The frequent presence of cloud cover in polar regions limits the use of the Moderate Resolution Imaging Spectroradiometer (MODIS) and similar instruments for the investigation and monitoring of sea-ice polynyas compared to passive-microwave-based sensors. The very low thermal contrast between present clouds and the sea-ice surface in combination with the lack of available visible and near-infrared channels during polar nighttime results in deficiencies in the MODIS cloud mask and dependent MODIS data products. This leads to frequent misclassifications of (i) present clouds as sea ice or open water (false negative) and (ii) open-water and/or thin-ice areas as clouds (false positive), which results in an underestimation of actual polynya area and subsequently derived information. Here, we present a novel machine-learning-based approach using a deep neural network that is able to reliably discriminate between clouds, sea-ice, and open-water and/or thin-ice areas in a given swath solely from thermal-infrared MODIS channels and derived additional information. Compared to the reference MODIS sea-ice product for the year 2017, our data result in an overall increase of 20 % in annual swath-based coverage for the Brunt Ice Shelf polynya, attributed to an improved cloud-cover discrimination and the reduction of false-positive classifications. At the same time, the mean annual polynya area decreases by 44 % through the reduction of false-negative classifications of warm clouds as thin ice. Additionally, higher spatial coverage results in an overall better subdaily representation of thin-ice conditions that cannot be reconstructed with current state-of-the-art cloud-cover compensation methods.
Presencia del feminismo institucional en YouTube: estrategia de difusión de la información y ¿movilización de la ciudadanía?
Authors: Sánchez-Labella Martín Inmaculada , Romo Parra Carmen
Published: March 2021

En la sociedad actual el fácil acceso a la información online es una necesidad creciente. Sobre esta evidencia, y dada la escasez de investigaciones acerca de la información pública sobre igualdad de género dentro del espacio virtual, en el presente estudio abordamos el análisis de los canales de Youtube de los institutos de la mujer españoles. Así, y habiendo comprobado cuáles son las comunidades autónomas que cuentan con organismos de este tipo con canal propio, se confeccionó una ficha de análisis que, a través de una batería de indicadores, arrojó datos sobre la disposición, el uso y la gestión de la información, así como del tipo de contenidos, la interacción y el engagement generado. Fijamos el intervalo de estudio entre abril de 2018 y el primer trimestre del 2020. Los resultados muestran que, a pesar del importante trabajo realizado por estos organismos en el terreno de la igualdad de oportunidades entre mujeres y hombres, estos no están valorando en su justa medida las posibilidades que ofrece YouTube para consolidar su labor, ya que no suelen usar este medio con una intención comunicativa bidireccional ni interactiva con sus followers. De este diagnóstico, pues, se deriva una conclusión general: afianzar las políticas de igualdad requiere de la construcción de redes online que sean vehículo de información veraz y diálogo constante con la ciudadanía. De ello depende en gran medida el nivel de liderazgo de las instituciones que tratamos en nuevos entornos comunicativos, susceptibles de ser poderosos instrumentos para la lucha contra el sexismo y para el avance de la equiparación entre géneros.
Empoderamiento y resistencia de las mujeres desplazadas víctimas del conflicto armado colombiano del barrio Pinar del Río (Barranquilla)
Authors: Buitrago Echeverry Carolina
Published: March 2021

El conflicto armado colombiano ha dejado a 33.000 personas desplazadas sólo en 2019. Esta investigación se centra en los riegos específicos del conflicto basados en el género: violencia, explotación o abuso sexual, esclavización para ejercer labores domésticas, reclutamiento de hijos a temprana edad. Mediante una etnografía, se observa una serie de impactos que tienen que ver con la invisibilización de las mujeres en sus procesos organizativos. Se halla que la violencia del conflicto es también una forma de colonialismo de poder, que las relega al eslabón más bajo de la cadena social. Exfoliadas de un palimpsesto de marginalidades: racismo (muchas de ellas son afro o indígenas), aporofobia, machismo, periferia, tienen, además, la dificultad de ser reconocidas como sujeto de derecho con el fin de poder beneficiarse de las políticas públicas. Ponemos de relieve sus luchas por convertirse en actoras políticas.