bluuebunny/crossref_metadata_2025 huggingface dataset:
Preparation and Characterisation of Liposomal Formulations of Levamisole and Albendazole Used in Veterinary Medicine
Authors: Susar Hasan , Çelebi Murat , Çelebi Çağla , Çoban Özlem , Şen Hüseyin , Karahan İzzet
Published: August 2024

The aim of this study is to by converting albendazole and levamisole, which are antiparasitic drugs used in both humans and animals, into liposomal formulations under laboratory conditions. To ascertain the circumstance in practice, characterization studies were additionally conducted. The study was performed by modifying the hydration of the thin lipid film. Experiments were carried out with egg phosphatidylcholine, cholesterol, chloroform and methanol in different amounts. Albendazole and levamisole formulations were made with the substances used in liposomes. Zeta potential, polydispersity index, encapsulation efficiency, particle size measurements and scanning electron microscopy were performed as part of characterization studies. The results show that Lipo LVM has the smallest particle size value at 380.87 ± 19.52 nm, whereas Lipo LVM–PBS has the largest particle size value at 7236.67 ± 443.89 nm. Values for the polydispersity index fall between 0.527 and 0.896. Zeta potential levels, on the other hand, range from -7.6 mV to -46.8 mV. While this value was determined as -8.2 ± 0.4 mV in LD Lipo ABZ and -18.4 ± 0.6 mV in HD Lipo ABZ, respectively. Both HD Lipo ABZ and LD Lipo ABZ have polydispersity indices for ABZ of 0.529 ± 0.066 and 0.896 ± 0.085, respectively. It was found that the particle size rose as the desired amount of liposomal albendazole increased. It was found that the liposomization of albendazole was higher than that of levamisole. Albendazole and levamisole liposomal formulations were successfully developed in the investigation. By carrying out characterization studies, it was discovered that it may be employed in clinical trials. In the upcoming years, it is anticipated that continuous research in the field of nanotechnology will improve human and animal health and aid to more effectively control parasite infestations.
Detección de anticuerpos contra el virus de Diarrea Viral Bovina (VDVB) en tanques de leche en la Provincia de El Oro, Ecuador
Authors: Aguilar–Gálvez Fernando , Román-Olaya Anthony , Sánchez-Prado Robert , Ludeña-Jiménez Iván , Dus-Santos María José , Carruyo–Núñez Gabriela
Published: August 2024

La diarrea viral bovina (DVB) es una enfermedad infecciosa crónica causada por el virus de la diarrea viral bovina (VDVB), miembro del género Pestivirus de la familia Flaviviridae. La misma se asocia con una amplia gama de manifestaciones clínicas produciendo pérdidas económicas significativas en la industria ganadera a nivel mundial, principalmente debidas a fallas reproductivas. En la Provincia de El Oro no existen estudios que evidencien de manera directa o indirecta la circulación del VDVB. Sin embargo, estudios de seroprevalencia en otras provincias del país sugieren una amplia circulación viral. El objetivo de este trabajo fue evidenciar la presencia de anticuerpos específicos para VDVB excretados en leche de vacas en producción en pequeños establos en la Provincia de El Oro (Sur del Ecuador), haciendo uso del kit comercial de Elisa de bloqueo para diagnóstico CIVTEST® BOVIS BVD/BD p80 (Laboratorios HIPRA, Spain). Para ello se realizó la toma de 34 muestras de leche en tanques de almacenamiento y se analizaron mediante el uso de este kit. Hubo una alta frecuencia de detección del 52,94 %, de anticuerpos contra VDVB, lo que evidencia de manera indirecta la circulación del virus de diarrea viral bovina en la zona de estudio. El cantón El Guabo presentó la mayor frecuencia de muestras positivas con 100 % de presencia de anticuerpos, el Cantón Chilla con 42,84 % y Santa Rosa con 37,5 %. El Cantón con menor prevalencia fue Machala con 25 %. Estos resultados permiten evidenciar la circulación del VDVB en los predios estudiados ya que, en los mismos no se aplican vacunas contra DVB dentro de sus planes sanitarios. Se recomienda llevar a cabo estudios epidemiológicos enfocados en evaluar el alcance de esta enfermedad y los problemas reproductivos que pueda generar en los rebaños del país. Igualmente, establecer programas de control sanitario y perfiles reproductivos en las diferentes ganaderías para mejorar su rendimiento productivo.
Identification of variants in GBP1 and GBP5 Genes associated with susceptibility and resistance to porcine reproductive and respiratory syndrome in Uruguayan Creole pigs
Authors: Montenegro María del Carmen , Nariné Nariné , Freire Bibiana , Carballo Cecilia , Llambí Dellacasa Silvia
Published: August 2024

Porcine reproductive and respiratory syndrome (PRRS) is a viral disease that affects pigs, causing significant economic losses in the global swine industry due to reproductive and respiratory problems. The causative agent of PRRS is the PRRS virus (PRRSV), primarily transmitted through direct or indirect contact via respiratory or oral routes. Despite biosecurity measures, monitoring, and vaccination, there is currently no fully effective vaccine against this virus. Research has identified a quantitative trait locus on chromosome 4 associated with PRRSV resistance. This locus includes genetic polymorphisms rs80800372 (WUR) and rs340943904 in the GBP1 and GBP5 genes, respectively. PRRSV has been detected in South America, including Uruguay in 2017. In Uruguay, the Pampa Rocha pig is the only breed of Creole pigs and is at risk due to its small population. In this context, the objective was assessing genetic variability in the Pampa Rocha breed for relevant variables related to PRRS resistance. The study determined the genotype for these variants using the end–point PCR technique, followed by Sanger sequencing. In the study, corresponding alleles were identified for each variable of interest, with allele frequencies of 0.825 for the A allele and 0.175 for the G allele in rs80800372 (WUR), and 0.825 for the G allele and 0.175 for the T allele in rs340943904. The variants are in Hardy Weinberg equilibrium and there is a linkage disequilibrium between them. The study highlights an increase in the frequency of favorable alleles related to PRRSV resistance in Pampa Rocha creole pigs. These findings underscore the importance of using molecular markers to identify PRRS–resistant animals, which could be beneficial for both pig production and animal welfare.
A field study on rational choice of medication: The use of Tilmicosin and Cefquinome in ovine footrot treatment
Authors: Yıldız Ferit , Gençcelep Musa
Published: August 2024

In veterinary medicine, it is extremely important to use drugs that will not put human health at risk. In the treatment of animal diseases, the preference of drugs that accumulate in muscle tissue (meat) and are excreted from the body with milk because they create low treatment costs poses a public health and food safety risk. Veterinarians and animal breeders should pay attention to the use of drugs that do not leave residues in animal foods in the treatment of diseases of animals whose meat is eaten. With this study, it was aimed to reveal the healing time of Tilmicosin, which passed to milk and Cefquinome, which is not passed to milk are used in the treatment of footrot, especially in sheep raised for meat and milk, and what are the costs (medicine, labor, etc.) of both drugs to animal owners. The study was conducted on 80 sheep with footrot from sheep raised in Muş, Türkiye in 2020-21. As a result of field observations, anamnesis and clinical examinations, sheep with footrot were divided into two groups in equal numbers. One group was administered Cefquinome (1 mL·50 kg-1 im. every 24 hours –h–, 3 applications), while the other group was administered Tilmicosin (1 mL·30 kg-1 sc. 48 h later, 2 applications) and the animals were observed for 10 day (d). In the Cefquinome group, footrot could be treated at a rate of 90% on the 4th d and did not bring additional costs to the animal owners. It has been concluded that Cefquinome should be preferred in treatment in terms of animal health, food safety and public health due to its high treatment success, easy application in pasture conditions, and the availability of milk during treatment.
Evaluation of the application and effects of intratesticular use of vaseline and acetylsalicylic acid 30% + vaseline for chemical castration in male rats
Authors: İşler Cafer Tayer , Bakır Onur , Uyar Ahmet , Güvenç Mehmet , Yalçın Oğuz Kaan
Published: August 2024

The aim of this study was to evaluate the application and effects of intratesticular use of a mixture containing vaseline and 30% acetylsalicylic acid for chemical castration in male rats. Twenty–eight male albino Wistar rats were divided into four groups: control, sham, vaseline, and vaseline + 30% salicylic acid mixture. The control group (K) received no injection, the Sham group (S) was injected with 1 mL of saline, the vaseline group (V) was injected with 1 mL of vaseline, and the vaseline + acetylsalicylic acid group (V+ASA) was injected with 1 mL of a mixture containing 30% acetylsalicylic acid and vaseline. A statistically significant difference (P=0.000) was determined between the vaseline (V) and vaseline + acetylsalicylic acid (V+ASA) groups. The Malondialdehyde (MDA) value of the vaseline group was found to be higher (3.197 ± 0.08) with a statistically significant difference (P=0.000) compared to the other groups. In terms of glutathione (GSH) value, a statistically significant difference (P<0.05) was observed in the V+ASA group compared to the V and K groups. When comparing glutathione peroxidase (GSH–Px) levels. There was a significant difference (P=0.013) between the vaseline (V) and control (K) groups. A statistically significant difference (P=0.046) was found between the vaseline (V) and vaseline + acetylsalicylic acid (V+ASA) groups in terms of catalase (CAT) activities. In terms of motility in spermatological examination, it was determined that the vaseline (V) group had the lowest rate with 11,250 ± 3.14, showing a statistically significant difference (P=0.001) compared to the other three groups. The group with the highest sperm concentration was K (82,000 ± 6.60), while the lowest concentration was observed in group V (27,600 ± 3.54). The dead/viable ratio in semen was found to be the lowest (7,200 ± 2.03) in group K and the highest (61,250 ± 13.16) in group V. The highest rate and statistical difference in a chromosome values were determined in the vaseline (V) group. Histopathologically, the morphology of the testicular tubules was impaired in the vaseline (V) and vaseline + acetylsalicylic acid (V+ASA) groups, observed as degenerated and necrotic. Degenerated tubules were observed, devoid of germinative epithelial cells and consisting only of basal membrane. In conclusion, the castration process was performed irreversibly in the vaseline (V) and vaseline + acetylsalicylic acid (V+ASA) groups.
Molecular characterization of ovine parapoxviruses in Türkiye: phylogenetic overview
Authors: Karapinar Zeynep , Gürses Murad
Published: August 2024

The genus Parapoxvirus of the family Poxviridae is the causative agent of the Ecthyma Contagiosum (Orf virus) disease, which is widespread in sheep and goats around the world. The Orf virus is also recognized as an occupational zoonotic agent, causing auto limited lesions in humans. The Orf virus has an affinity for epithelial tissue and causes proliferative lesions around the lips and nose, udder, and hairless areas of the skin. In this study, the positivity of the virus was investigated by PCR in samples collected from several provinces in different regions of eastern and western Türkiye. Molecular characterization of the samples identified as positive by PCR was performed based on the B2L gene region. A phylogenetic tree was constructed by comparing the obtained partial B2L gene sequences with the reference parapoxvirus strains obtained from GenBank. It was found that the strains obtained in the study were close to Iranian and Sudanese strains. When the deduced amino acid sequences of the strains obtained with the reference strains taken from GenBank were compared, amino acid changes were detected at two different points. The phylogenetic map showed that different variants were likely to have circulated in different parts of the country. This study provided up–to–date information on Orf virus strains circulating in different regions of the country.
Influence of lambing type on body weight changes and productive efficiency of Blackbelly × Pelibuey multiparous ewes in lactation
Authors: Morales–Carrillo Benigno , Castillo–Linares Erika Belem , García–Osorio Irma del Carmen , Oliva–Hernández Jorge
Published: August 2024

Durante la lactancia las ovejas tienen una alta demanda de nutrientes, que frecuentemente no es cubierta mediante el consumo voluntario en pastoreo, situación que origina una reducción del peso vivo. El objetivo fue determinar la influencia del tipo de parto y número de semanas posparto sobre el cambio de peso vivo de ovejas de pelo multíparas y el de sus corderos durante la lactancia. El estudio se realizó con información productiva de 11 ovejas Blackbelly x Pelibuey en su cuarto parto y sus 17 corderos. Las ovejas y corderos se pesaron al parto y cada siete días hasta el día 56 posparto, y se determinó la ganancia diaria de peso. Se utilizaron los procedimientos GLM y MIXED para el análisis estadístico. El tipo de parto afectó el peso vivo de las ovejas al día 56 postparto, ganancia de peso total y diaria durante la lactancia (P<0.05) y su eficiencia prodcutiva (P<0.01). El número de semana posparto afectó la ganancia diaria de peso de ovejas y corderos (P<0,01). El tipo de parto x número de semanas posparto no influyeron (P>0,05) sobre la ganancia diaria de peso de los corderos. Se concluyó que en ovejas Blackbelly x Pelibuey multíparas, el tipo de parto explica la variación en los cambios de peso y eficiencia productiva de las ovejas. Mientras que el número de semanas posparto explica la variación en la ganancia diaria de peso de las ovejas y corderos.
Comparative study of chemical composition Antioxidant and Antimicrobial activity of Methanolic Extracts of Mentha rotundifolia
Authors: Ferdjioui Siham , Belhattab Rachid
Published: August 2024

Mentha rotundifolia is a member of the Lamiaceae family and is distributed mainly in traditional medicine in Algeria and the Mediterranean locality. This study aimed to demonstrate how the extraction technique can determine the type of active ingredients obtained, as well as their potential pharmacological and therapeutic effects. The methanolic extracts were obtained by maceration and Soxhlet apparatus. The study of the chemical composition was determined by colourimetric methods and liquid chromatography–mass spectrometry (LC–MS/MS); the antioxidant activity was evaluated in vitro by three tests: DPPH test, ferrous ion chelating test and reducing power test. The antimicrobial effect of extracts was evaluated by agar diffusion assay against six microbial strains. The results demonstrate that the best yield of extraction, Total phenolic and flavonoid contents, and antioxidant activity were found to be higher in the extract obtained by Soxhlet than those obtained by maceration. The phytochemical screening tests identified polyphenols, flavonoids, tannins, terpenoids, and quinones, and anthraquinones and saponins were absent in both extracts. The LC–MS/MS revealed the presence of several phenolic compounds, the predominant in both extracts was rosmarinic acid. The antimicrobial activity shows that both extracts have no effect. In conclusion, this study reveals that extraction by Soxhlet is more suitable than extraction by maceration for this plant.
Effect of protein sources on the antioxidant metabolism of visceral organs of Morkaraman lambs
Authors: Can Mazhar Burak , İmik Aybuke
Published: August 2024

The selection of protein sources plays a significant role in meeting the dietary requirements of animals and addressing specific nutritional needs. This study was designed to determine the effects of different protein sources incorporated into lamb diets on the antioxidant metabolism of the lung, heart and kidney tissues by means of the measurement of GSH and LPO levels and SOD, CAT and GPx activities. For this purpose, 24 male Morkaraman lambs were randomly assigned to 3 groups, each of 8 animals. The dietary protein sources provided to the animals were soybean meal + safflower meal in the control group (SSG), wheat gluten in the wheat group (WG), and corn gluten in the corn group (CG). The diets fed to each group were formulated to be isonitrogenous (17% crude protein/CP) and isocaloric (2700 kcal·kg-1 ME). In the lambs fed on the diet supplemented with wheat gluten, it was determined that SOD activity in the lung (P<0.05) and heart (P<0.01) tissues, CAT activity in the lung and heart tissues (P<0.01), and GPx activity in the kidney and heart tissues (P<0.01) had significantly increased. In the lambs fed on the diet supplemented with corn gluten, statistically significant increases were detected in the SOD activity of the lung (P<0.05) and heart (P<0.01) tissues, CAT activity of the lung, heart and kidney tissues (P<0.01, P<0.05), and GPx activity of the kidney and heart tissues (P<0.01, P<0.05). The lambs fed on the gluten–supplemented diets presented with statistically significant decreases in the LPO levels of the lung tissue (P<0.01, P<0.05), and the GSH levels of the lung, heart and kidney tissues (P<0.01). In result, it was ascertained that, when fed on diets supplemented with wheat gluten and corn gluten, the antioxidant metabolism of the lung, heart and kidney tissues were significantly affected in lambs.
Implementasi Pendekatan Behaviorisme Dalam Pemberian Reward Untuk Membentuk Karakter Disiplin Anak Usia Dini
Authors: Puspita Yenda , Fitriana Fitriana , Akhyar Yundri
Published: August 2024

Problems that occur when the child's attitude and behavior are not disciplined towards the character when carrying out activities. This is determined by methods or aspects of development that are not yet optimal, there are still children who do not have a disciplined character such as not applying attitudes when entering the toilet, fighting over toys with friends. This article aims to find out the behaviorism approach in reward prizes to shape the disciplined character of early childhood. Using the reward method to shape the character of discipline in children means the perfect way to give way or bridge disciplined students. The method used in this research is descriptive qualitative research method, descriptive method already exists a method that describes any conditions or symptoms that are in accordance with the events that occur in the field when the research is carried out. Descriptive method is research that provides a systematic, actual, and accurate description. about the news and the correlation between the phenomena studied. The results of the study found that using the behaviorism approach to rewards can produce disciplined character in early childhood. because it is very influential on various aspects of development, especially for learning to be responsible for using what is done, can control themselves and can motivate children to do the activity themselves
Optimalisasi Perkembangan Motorik Kasar Pada Anak Melalui Permainan Tradisional Egrang Tempurung Kelapa
Authors: Hasna Saffanatun , Susanti Lizza
Published: August 2024

The existence of this research is motivated by the lack of proficiency in early childhood in recognizing and sorting numbers. An effort that can be done is to use a smart board. This use is intended to help facilitate early childhood in improving their cognitive abilities. This study aims to help children aged in the development of cognitive skills through the method of matching numbers on a smart board. This study uses a qualitative method in a descriptive way. The results of the study show that the smart board method can help children to optimize their cognitive skills, the achievement of this method is quite good. The results of this study can be used as an alternative to the selection of models in the development of children's cognitive abilities about numbers.
Perkembangan Sosial Emosional Anak Usia Dini Di Raudhatul Athfal Lii Muttaqin
Authors: Guswanti Nelia , Rayahu Evi , Nurwulan Sari Dwi
Published: August 2024

The research is conducted as the Early Childhood Students at RA Lil Muttaqin Tapung Kampar have problems in socialization, sharing toys, taking turn in playing, expressing the feelings, and lack ability to communicate with peers. This research purpose was to determine the early childhood students’ socio-emotional development levels at RA Lil Muttaqin Tapung Kampar. The research used qualitative research method. The data analysis was used quantitative to test hypotheses. The research was used observation, interviews and documentation techniques. Social Emotional Development is a mental change that takes place gradually and in a certain time, from the simple ability to more complex abilities. Development is a process of changing or improving something towards a complex and psychological nature. Development and growth are two different things but development is related to growth. The indicators of the social emotional development of early childhood students are self-awareness, managing emotions, utilizing emotions productively, empathy, and building relationships. After testing the validity, reliability and descriptive statistics form the early childhood students’ socio-emotional development at RA Lil Muttaqin Tapung Kampar was in “good” category at 9.3 and 130 respectively. The minimum value was 7 and the maximum value was 10 for all indicators. The early childhood students’ socio-emotional development at RA Lil Muttaqin Tapung Kampar was very good
Penggunaan Permainan Bakiak Dalam Meningkatkan Motorik Kasar Kelompok B TK Mutiara Kecamatan Siak Hulu Kabupaten Kampar
Authors: Tryana Nofita , Inmaryanto Inmaryanto , Sari Meiliza
Published: August 2024

This research was conducted in two cycles and each cycle was conducted in two meetings. In order to ensure the research run well, the researcher arranges the stages that are passed in classroom action research, : 1) Action planning/preparation, 2) Action implementation, 3) Observation, and 4) Reflection. The subjects in this study were 14 students of  B1 class  consist of  8 girls and 6 boys in the first semester of the 2021/2022 academic year at  TK Mutiara, Siak Hulu, Kampar.Meanwhile , the object of this research was the use of clogs game to improve gross motor skills of early childhood students . The research data were collected through teacher observation techniques and early childhood student's activities and documentation. After the data was collected through observation, the data was processed using the percentage formula. The results of this study are there is an increasing in the learning process which carried out by teachers and early childhood student's gross motor skills. Observation of children's activities also increased, It reveled from the initial data to cycle II meeting 2. Initial data was 43.83%, Cycle II meeting 2 obtained 86.36%. So that the overall increase in early childhood student's gross motor activity is  42.53%
EKSPLORASI PERKEMBANGAN BAHASA ANAK USIA DINI: ANALISA FAKTOR, INDIKATOR, DAN TAHAPAN PERKEMBANGAN
Authors: Sofia Zahra  , Masganti Sit
Published: August 2024

Language development is one of the many areas of development that needs to be addressed in kindergarten. Language as a systematic and orderly system of pronunciation, ideas and emotions used for speaking, listening, reading and writing to communicate with other people. This research focuses on analysis related to early childhood language development, through the stages of development, the factors that influence children's language development, as well as indicators of children's language development and various theories of language development. The purpose of this research is to analyze matters related to children's normal development, this is because various problems often arise that children experience when they struggle with acquiring good language. The method used in this research is a qualitative method in the form of library research. The results of this research concluded that it is important to understand children's language development because the development of young children goes through 4 stages, namely pre-imgistic, single words, two-word sentences, and short sentences. Language and language development are important aspects of life, related to child development issues, the role of parents and teachers is an important factor in language development, because they must be good at stimulating children's language intelligence.
Editorial
Authors: Barrera Juana
Published: August 2024

Editorial realizada en 1999 para el primer número de la revista. El cuerpo editorial estaba compuesto por Mariangela (Directora), Zulema de Barbieri (subdirectora), Juana Barrera (Editora); Casandra Araya, Rafael González, Pamela Tomicic, Carmen Julia Coloma, Luis Romero y Selma Alfaro (Comité Editorial); Cecilia Valenzuela (Periodista); María de la Luz Gómez y Luis Ortega (Diseño y Diagramación).
Audiometría de tronco encefálico utilizando diferentes polaridades de presentación del estímulo
Authors: Da Silva Cristiane
Published: August 2024

La audiometría de tronco encefálico (ABR) es un examen objetivo complementario a los procedimientos audiológicos de rutina en el diagnóstico de las alteraciones auditivas. El objetivo de este trabajo es comparar las amplitudes y las latencias absolutas de las ondas I, III, V e intervalos I-III, utilizando diferentes polaridades de presentación del estímulo acústico. Participaron 50 individuos adultos sin antecedentes otológicos, evaluados con ABR y presentación del estímulo acústico con polaridad de rarefacción y de condensación. Existen diferencias significativas al usar los diferentes tipos de polaridad de condensación y rarefacción, cuando fueron comparadas de un modo global. La polaridad del estímulo acústico, rarefacción o condensación, así como los diversos parámetros utilizados en el ABR, deben ser tenidos en cuenta en el análisis de los datos, garantizando así que este procedimiento sea un instrumento seguro para la obtención de resultados precisos y confiables.
Relación entre comprensión del lenguaje figurado y rendimiento escolar en estudiantes de enseñanza básica
Authors: Barrera Juana
Published: August 2024

El proposito del presente trabajo es conocer la relacion que existe entre la comprension del lenguaje figurado y el desempeiio escolar en ninos de 4°, 6° y 8° ano de educacion general basica. Para ello, se sometio a los ninos a tareas de comprension de modismos y refranes. Es decir, expresiones de significado no literal. Los resultados indican que existen diferencias de rendimiento por curso, tanto en modismos como en refranes evidenciando que a medida que se avanza en escolaridad mejora e1 enfrentamiento con este tipo de tarea metalinguistica. Se establece ademas, que en los tres cursos considerados en esta investigacion existe relacion entre e1 rendimiento en tareas de comprension de lenguaje figurado y el rendimiento escolar en diversas asignaturas. Se discute en relacion a estos resultados y su implicancia para e1 trabajo escolar.
Las edades óseas y cronológicas como determinantes clínicos de la involución de los tejidos adenoideos
Authors: Firmani Mónica , Gómez Braulio , Calderón Nedy
Published: August 2024

El tejido adenoideo aparece como parte del anillo linfático de Waldeyer durante los primeros anos de vida. Alcanza su máximo volumen a los 6 anos de edad, comienza a desaparecer entre los 8 a 10 anos de edad, reduciéndose a una pequeña cavidad faríngea en adultos. En presencia de adenoides hipertróficos, pueden existir alteraciones respiratorias y de crecimiento general en el niño.
Para determinar patrones de involución adenoidea, fueron medidas áreas de tejido adenoideo y nasofaríngeas, usando telerradiografías de perfil, según el método de Handelman y Osborne.
La edad ósea fue obtenida a través del análisis de madurez ósea de Bjork y Helm en radiografías de mano, comparadas con el atlas de madurez ósea de Canals.
Se seleccionó una muestra de 5 grupos, cada una con 20 individuos entre 10 y 14 años de edad. Los resultados fueron analizados mediante regresión lineal y validados con análisis de varianza.
Cuestionario sobre la interacción comunicativa niño/adulto
Authors: Martínez Luis , Maggiolo Mariangela
Published: August 2024

El propósito del cuestionario es obtener información sobre la comunicación que se establece entre el niño y el adulto (la madre o cualquier adulto que lo cuida regular-mente). Interesa conocer cuánto sabe el adulto respecto a sus propias habilidades y a las habilidades del niño cuando ambos se comunican entre sí. El cuestionario incluye dos secciones. La primera comprende los datos de identifi-cación del niño/niña, del profesional que solicita la información a los padres y un ítem de observaciones. La otra sección contempla una serie de preguntas sobre las habilidades comunica-tivas del niño cuando interactúa con el adulto. En la segunda sección se incluye una serie de preguntas sobre las habilidades comunicativas del adulto o cuidador cuando interactúa cón el niño. Todas las preguntas deben ser respondidas por el adulto o cuidador del niño.
La intervención y el apoyo en el lenguaje en contextos inclusivos
Authors: Acosta Victor
Published: August 2024

El presente trabajo tiene por objetivo presentar las bases para la intervención y el apoyo en el lenguaje en contextos inclusivos. Se hace hincapié en la necesidad de manejar adecuadamente determinados partos de interacción así como la exigencia de focalizar la intervención teniendo en cuenta el currículo escolar. El apoyo fonoaudiológico debe estar cimentado en estrategias como el andamiaje, el modelado interactivo alrededor de los distintos grupos sociales que conviven dentro del aula; para tal fin se sugiere el uso del apoyo por pares y las estructuras de aprendizaje cooperativas.
El proceso lector normal y alteraciones en su desarrollo según el modelo propuesto por M. Coltheart
Authors: Bermeosolo Jaime
Published: August 2024

Este artículo examina el modelo del sistema adulto lector hábil propuesto por Max Coltheart, útil para caracterizar los diferentes tipos de dificultades del desarrollo de la lectura, en cuanto a las sub-habilidades puntuales en que el niño tiene problemas al aprender a leer. Entre las habilidades que los niños tienen que lograr para llegar a ser lectores competentes están el reconocimiento de letras y de palabras totales, el conocimiento de las reglas de relación letra-sonido, y el acceso al significado desde la palabra impresa. Coltheart las considera los "bloques fundantes de la lectura". El modelo puede ser utilizado también para desarrollar procedimientos sistemáticos para evaluar cuán bien un niño está adquiriendo cada una de las subhabilidades, y para la selección o el diseño de procedimientos de intervención.
La voz del cantante: una integración de ciencia y arte
Authors: Guzmán Marco
Published: August 2024

La fisiología y la técnica de la voz cantada, es un campo poco abordado por los especialistas de la voz. Para poder comprender todos los procesos involucrados, no sólo se requiere conocimiento teórico, sino también una experimentación personal práctica. De esta forma, se posibilita una adecuada evaluación e intervención fonoaudiológica, en pacientes cantantes que presentan alteraciones de la voz. En este artículo se exponen los aspectos más relevantes y diferenciadores de la voz cantada, considerando parámetros respiratorios, de emisión y resonancia.
Las dificultades específicas de aprendizaje en lectura y su relación con habilidades lingüísticas en contextos socioeconómicos diversos
Authors: Infante Marta
Published: August 2024

El presente artículo muestra un estudio realizado sobre las diferencias en el desempeño de 72 alumnos con dificultades específicas de aprendizaje en lectura provenientes de escuelas municipales y colegios particulares en tareas de decodificación, comprensión lectora y comprensión oral. Los resultados indican que los alumnos de escuelas municipales presentan un desempeño inferior que aquellos de escuelas particulares en todas las tareas evaluadas. El análisis de la información evidencia la presencia de distintos perfiles de desempeño dependiendo del tipo de escuela al que pertenecen los alumnos. Del mismo modo, se investigaron relaciones entre las ha-bilidades de lectura y comprensión oral y el tipo de dependencia de las escuelas (municipal, particular) en los alumnos con dificultades específicas de aprendizaje en lectura. Los resultados sugieren la necesidad de abordar explícitamente la relación entre las habilidades de decodificación, comprensión lectora y comprensión oral en las prácticas educacionales.
Social Pedagogy in Germany – Contemporary Problems and Trends
Authors:   Sofia University, Pironkova Marina
Published: August 2024

This article explores the problems in the development of social pedagogy in Germany over the last three decades, analysing the features and trends in three directions: social pedagogy as a science, as a professional field and as the training of professionals. The main social pedagogical theories are analysed in the context of their common descriptive and normative aspects. The problems of the expanding field of realization of social pedagogy as a profession and the peculiarities in the training of specialists in the united specialty Sociale Arbeit are highlighted.
Content Dimensions of the Educational Profile of the Social Educator
Authors:   Sofia University, Ranev Aleksandar
Published: August 2024

The article is aimed at clarifying one of the essential aspects in the professional profile of the social pedagogue, namely his educational role and functions. The work of the social pedagogue is primarily aimed at helping people, groups, communities at risk in the direction of improving the quality of life, social inclusion, self-realization. Therefore, the training of the specialists to provide educational support is essential for their success. The material examines different approaches to structuring the profile of social pedagogues, including philosophy, competence and culture, and, based on theoretical and empirical data, their content elements are argued.
Correct Organization and Problems in the Process of Building the Subject-Developmental Environment in the Kindergarten through the Lens of the Competence Approach
Authors: Delcheva Nadia
Published: August 2024

In the present work, the influence and stages of the correct organization of the subject-developing environment and its connection with the competence approach in the process of forming the key competences among children in kindergarten are traced. The scientific research reveals the basic principles and stages that are embedded in the fundamental structure of building the subjectdevelopmental environment, as well as the advantages of the competence approach included in the learning process in the preschool stage of education. Models of the types of developmental environments in preschool education are proposed, as well as the stages of building the subject-developmental environment in preschool education. Opinions on the subject are summarized and recommendations are given for the organization of the subject-developmental environment.
Bruxismo, nomofobia e transtorno de déficit de atenção e hiperatividade em estudantes de odontologia
Authors: Silva Brenda Camilly , Santos Maria Eduarda Rodrigues , Pereira Camila Santos , Domingos Patrícia Luciana Batista , Guimarães Talita Antunes , Guimarães Luís Fernando , Santos Neto Pedro Eleutério , Oliveira Michelle Pimenta , Gonçalves Jaqueline Teixeira Teles , Oliveira Marcos Vinícius Macedo de
Published: August 2024

A nomofobia, causada pelo medo ou ansiedade decorrente da falta do celular, causa inquietação, ansiedade, estresse, raiva e tensão, o que pode favorecer o aumento dos sintomas de bruxismo, caracterizada como o apertar e ranger dos dentes. O TDAH – transtorno de déficit de atenção e hiperatividade – vem sendo também, associado ao uso excessivo dos smartphones, por acarretar sintomas de desatenção semelhantes aos do transtorno. O presente estudo objetivou analisar a relação do bruxismo com nomofobia e TDAH em estudantes de odontologia através de um estudo epidemiológico transversal conduzido com 198 acadêmicos, do primeiro ao quinto ano. Foi utilizada regressão logística binária para avaliar as chances de ocorrência de bruxismo em relação às variáveis investigadas, considerando intervalos de 95% de confiança, com nível de significância de 5%. A amostra apresentou uma alta prevalência de sinais e sintomas de bruxismo, TDAH e nomofobia. Mulheres e indivíduos com sinais e sintomas de moderados a grave de nomofobia apresentaram chances aumentadas de apresentarem bruxismo. Conclui-se que no ambiente acadêmico, pode haver elevada ocorrência dessas condições, uma vez que há vários estressores que tendem a aumentar a ansiedade e dificuldade de concentração do estudante.
Relato de caso: colecistite xantogranulomatosa em uma suspeita de neoplasia de vesícula biliar
Authors: De Souza Silva Nathalya , Elias Kiyoshi Takano de Saidneuy Aldo , Pereira Gregory Christian , Pigozzi Cabral Rafael
Published: August 2024

A colecistite xantogranulomatosa é uma condição inflamatória rara e benigna da vesícula biliar, caracterizada por fibrose intensa devido ao acúmulo de histiócitos lipídicos na parede vesicular, resultando em sintomas clínicos pouco específicos. Este estudo descreve o caso de um paciente cujo diagnóstico histológico de colecistite xantogranulomatosa foi estabelecido após colecistectomia realizada devido à suspeita de neoplasia da vesícula biliar. Devido à apresentação clínica, o diagnóstico pré e intra-operatório pode ser equivocado devido à baixa suspeita inicial deste quadro.
Efeitos de diferentes intensidades de carga e intervalos de recuperação na produção de lactato
Authors: Gemin Vidal Rafael , Soares Martins Adir , Vieira Brandenburg Joelson
Published: August 2024

O presente artigo teve como objetivo analisar o comportamento do limiar de lactato quando imposto a diferentes cargas e intervalos de treinamento. A amostra do tipo não probabilística intencional foi composta por cinco indivíduos do sexo masculino com experiência em treinamento resistido. Os participantes foram submetidos a quatro protocolos distintos: Alta carga com intervalo longo; Alta carga com intervalo curto; Baixa carga com intervalo longo; Baixa carga com intervalo curto, nos exercícios agachamento livre e rosca direta. Observou-se que no agachamento livre o protocolo que apresentou maior concentração de lactato foi o baixa carga e intervalo longo enquanto com a rosca direta foi o baixa carga e intervalo curto, ao passo que no agachamento livre o limiar de lactato apresentou maior número quando comparado à rosca direta, além do mais, sobressaiu-se o número de repetições com os protocolos os quais o descanso era maior. Inesperadamente, na rosca direta os protocolos apresentaram pouca variação do limiar, enquanto no agachamento houve diferença significativa de um para o outro.
Amiloidose cardíaca: aspectos do manejo da insuficiência cardíaca no paciente com amiloidose
Authors: Kuranishi Maria Eduarda , Alonso Matheus Felipe , Ribeiro Soares Borges Larissa , Vieira Donzelli Renato , Peripolli da Silva Maria Eduarda , Cruz Meirelles Izadora , Russo Milan Nycollas , Martins de Medeiros Caylani Tatiara , Grippa Sant’Ana Paula
Published: August 2024

A amiloidose é uma patologia multissistêmica caracterizada pela deposição de proteínas fibrilares insolúveis no espaço extracelular em diferentes órgãos, como o coração, podendo culminar com insuficiência cardíaca com fisiologia restritiva, sendo seu tratamento de extrema importância. Este artigo é uma revisão de literatura e buscou analisar os efeitos dos fármacos usados no manejo do paciente com insuficiência cardíaca em concomitância à amiloidose cardíaca. O estudo foi realizado em seis etapas bem definidas, incluindo identificação do tema e estipulação da pergunta norteadora da pesquisa, estabelecimento de critérios de inclusão e exclusão de artigos na busca literária, definição das informações a serem extraídas dos estudos escolhidos, busca eletrônica dos artigos, avaliação e interpretação dos estudos incluídos na revisão e produção da revisão. Os resultados indicam o uso de diuréticos de alça, inibidores da enzima conversora de angiotensina II e/ou bloqueadores do receptor de angiotensina II e antagonistas mineralocorticoides como principais classes de fármacos, além de estudos em andamento de novas terapias, para insuficiência cardíaca em conjunto com amiloidose.
Universidades promotoras de saúde e ODS: Um relato de experiência
Authors: Castro Ennes Lucas Mateus , De Souza Keity Miranda , Vasconcelos Patrícia Defáveri , De Almeida Gilsirene Scantelbury , Toledo Noeli das Neves , Da Silva Nair Chase , Eleres Campos Larissa Aparecida
Published: August 2024

Objetivos: Descrever as ações de saúde desenvolvidas na Escola de Enfermagem de Manaus sob o enfoque da Universidade Promotora de Saúde. Métodos: Trata-se de um relato de experiência utilizando-se a observação participante e entrevistas com os coordenadores acadêmico, administrativo e de curso e com a representação do centro acadêmico da instituição de ensino superior. Resultados: Foram realizadas 4 entrevistas e observações no ambiente e identificadas 13 ações de promoção da saúde desenvolvidas na Escola de Enfermagem de Manaus. Considerações Finais: As ações de promoção de saúde são de cunho esportivo, pedagógico, social e com intervenções voltadas à área da saúde. Elas privilegiam a comunidade acadêmica e possuem frágil participação em sua elaboração. Assim, na perspectiva da gestão e representação estudantil acontecem de forma tímida, com potencial de otimização na medida em que forem melhor compreendidas e incorporadas por todos os segmentos.
Variabilidade morfoagronômica de variedades tradicionais de feijão-caupi na Amazônia Ocidental
Authors: Araújo Érica de Oliveira , Celino Martins Soraya , Vargas da Silveira Murilo , Ferreira Cota Andressa
Published: August 2024

Apesar da grande importância socioeconômica do feijão-caupi, ainda há pouca informação sobre as variedades locais e suas diferenças ecofisiológicas e morfofisiológicas. Assim, o presente trabalho teve por objetivo a descrição, classificação e seleção de variedades de feijão-caupi com potencial agronômico para o estado de Rondônia. O experimento foi conduzido em condições de campo, utilizando o arranjo de blocos casualizados, com vinte e cinco acessos tradicionais de feijão-caupi, na área experimental do Instituto Federal de Rondônia, Campus Colorado do Oeste, no município de Colorado do Oeste, RO. A descrição e classificação dos acessos permitiram concluir que a região Norte constitui um centro de conservação on farm de feijão-caupi cujo germoplasma possui alta variabilidade, principalmente em relação hábito da planta, coloração de folhas e flores e curvatura de vagens, indicando a necessidade do desenvolvimento de cultivares para diferentes sistemas de cultivo e condições edafoclimáticas.
significance of enhancing health workers' skills and knowledge in driving positive patient experiences
Authors: Alarjani Norah Owaydhah , Alharbi Nasser Hamoud Mohammed , Alshammari Muhaned Mohammed
Published: August 2024

The significance of enhancing health workers' skills and knowledge in driving positive patient experiences cannot be overstated. As patient experience positions continue to evolve, hospitals and healthcare organizations must prioritize the development of skills and qualifications required for these roles. To deliver a positive patient experience in the ED, it is crucial to manage patient expectations and enhance their perception of the care received, given the unique position of EDs in shaping a patient's first impression. Therefore, investing in the skills and knowledge of healthcare workers to drive positive patient experiences is not only beneficial for the patients but also for the clinicians and the healthcare system as a whole.
The cost-effectiveness on sedative medication and regular medication
Authors: Alamri Abdulaziz , Bawazeer Ahmad , Almotiri Tariq , Alharbi Sattam , Alshammari Delyal , Alnasser Bader , Alswayeh Hani
Published: August 2024

When it comes to managing various medical conditions, the choice of medication can have a significant impact on both the patient's well-being and the overall healthcare costs. Two broad categories of medications that are widely used are sedation-controlled medications and regular medications. Sedation-controlled medications are designed to provide a level of sedation or drowsiness, often used for conditions such as insomnia, anxiety, or pain management. Regular medications, on the other hand, are not primarily focused on inducing sedation and are used to treat a wide range of medical issues. The goal of this study is to identify the most cost-effective sedation-controlled or regular medication, taking into account factors such as efficacy, safety, and overall cost-effectiveness. By examining the available evidence and considering the various aspects of these medications, healthcare providers and patients can make informed decisions that optimize both clinical outcomes and financial considerations.
Effect of psychological first aid program on anxiety level and perceived stress among elder persons
Authors: Fahmei Tayser Bauomei , Eletreby Rania Rabie , Behilak Sahar Elsayed Gaber , Elkasaby Ghalia Elmoghazy , Abdelwahed Amal Yousef
Published: August 2024

Background: As the global population ages, there is increasing concern about mental health. Globally a large number of elder persons suffer from different mental disorders. Within aging, elder persons may experience certain life changes that impact their mental health, in such as anxiety and stress. Therefore, Psychological First Aid (PFA) as program intervention is designed to eliminate anxiety level and perceived stress among elder persons. Aim: Evaluate effect of psychological first aid program on anxiety level and perceived stress among elder persons. Design: a quasi-experimental research design pre-test post-test was used.  Subjects: A convenience sample of one hundred (100) elder persons fulfilled criteria included. Setting: The study was carried out at Al Sabeen Fadan primary health care center, Cairo governorate, Egypt. Tools: Socio-demographic and clinical data of community dwelling older adults structured interview questionnaire form, Visual Analog Scale and Perceived Stress Scale (PSS) Results: Psychological First Aid program has highly statistically significant effect on total improvement of anxiety level and perceived stress among elder persons. 46% &47% of elder persons were suffering from severe and extreme anxiety level respectively before program implementation compared with 64%& 36% had mild and moderated level of anxiety after program application (p= <0.001*).
Legislation and policy reform to combat drug addiction
Authors: Alamri Abdulaziz , Bawazeer Ahmad , Almotiri Tariq , Alharbi Sattam , Alshammari Delyal , Alnasser Bader , Alswayeh Hani
Published: August 2024

Drug addiction is a major public health crisis that affects individuals, families, and communities around the world. The negative impacts of drug abuse are far-reaching, including increased rates of crime, health problems, economic hardship, and social discord. Addressing the drug addiction epidemic requires a multi-faceted approach that combines prevention, treatment, and policy interventions. One key component of an effective strategy to combat drug addiction is legislation and policy reform. Lawmakers and policymakers play a crucial role in shaping the legal and regulatory environments that influence patterns of drug use and access to addiction treatment. This study examines how legislation and policy can be leveraged to reduce drug addiction and its associated harms.