bluuebunny/crossref_metadata_2025 huggingface dataset:
Rare-Earth Doped Gd3−xRExFe5O12 (RE = Y, Nd, Sm, and Dy) Garnet: Structural, Magnetic, Magnetocaloric, and DFT Study
Authors: Neupane Dipesh , Kramer Noah , Bhattarai Romakanta , Hanley Christopher , Pathak Arjun K. , Shen Xiao , Karna Sunil , Mishra Sanjay R.
Published: September 2023

The study reports the influence of rare-earth ion doping on the structural, magnetic, and magnetocaloric properties of ferrimagnetic Gd3−xRExFe5O12 (RE = Y, Nd, Sm, and Dy, x = 0.0, 0.25, 0.50, and 0.75) garnet compound prepared via facile autocombustion method followed by annealing in air. X-Ray diffraction (XRD) data analysis confirmed the presence of a single-phase garnet. The compound’s lattice parameters and cell volume varied according to differences in ionic radii of the doped rare-earth ions. The RE3+ substitution changed the site-to-site bond lengths and bond angles, affecting the magnetic interaction between site ions. Magnetization measurements for all RE3+-doped samples demonstrated paramagnetic behavior at room temperature and soft-ferrimagnetic behavior at 5 K. The isothermal magnetic entropy changes (−ΔSM) were derived from the magnetic isotherm curves, M vs. T, in a field up to 3 T in the Gd3−xRExFe5O12 sample. The maximum magnetic entropy change (−∆SMmax) increased with Dy3+ and Sm3+substitution and decreased for Nd3+ and Y3+ substitution with x content. The Dy3+-doped Gd2.25Dy0.75Fe5O12 sample showed −∆SMmax~2.03 Jkg−1K−1, which is ~7% higher than that of Gd3Fe5O12 (1.91 Jkg−1K−1). A first-principal density function theory (DFT) technique was used to shed light on observed properties. The study shows that the magnetic moments of the doped rare-earths ions play a vital role in tuning the magnetocaloric properties of the garnet compound.
Direct Aniline Formation with Benzene and Hydroxylamine
Authors: Liu Ningyu , Sleck Matthew D. , Jones William D.
Published: September 2023

A single-step method for aniline formation was examined. Using a vanadate catalyst with an iron oxide co-catalyst and hydroxylamine hydrochloride as the amine source, an up to 90% yield of aniline was obtained with high selectivity. Further study showed that the overall reaction was pseudo-second order in terms of hydroxylamine concentration. Regioselective H-D exchange experiments suggest that the C-N bond formation step occurs via an irreversible electrophilic pathway. Based on all of the key observations, a mechanism is proposed.
Defucosylated Monoclonal Antibody (H2Mab-139-mG2a-f) Exerted Antitumor Activities in Mouse Xenograft Models of Breast Cancers against Human Epidermal Growth Factor Receptor 2
Authors: Suzuki Hiroyuki , Ohishi Tomokazu , Nanamiya Ren , Kawada Manabu , Kaneko Mika K. , Kato Yukinari
Published: September 2023

The clinically approved human epidermal growth factor receptor 2 (HER2)-targeting monoclonal antibodies (mAbs), trastuzumab, and pertuzumab, target domains IV and II, respectively. Trastuzumab is now the standard treatment for HER2-overexpressed breast and gastric cancers, and trastuzumab in combination with pertuzumab showed clinical benefit. However, there still exist patients who do not respond to the therapy. Furthermore, HER2 mutants that cannot be recognized by pertuzumab were found in tumors. Therefore, novel anti-HER2 mAbs and modalities have been desired. In our previous study, we developed a novel anti-HER2 domain I mAb, H2Mab-139 (mouse IgG1, kappa). We herein produced a defucosylated mouse IgG2a type of mAb against HER2 (H2Mab-139-mG2a-f) to enhance antibody-dependent cellular cytotoxicity (ADCC)-mediated antitumor activity. H2Mab-139-mG2a-f exhibits a high binding affinity in flow cytometry with the dissociation constant (KD) determined to be 3.9 × 10−9 M and 7.7 × 10−9 M against HER2-overexpressed Chinese hamster ovary (CHO)-K1 (CHO/HER2) and HER2-positive BT-474 cells, respectively. Moreover, we showed that H2Mab-139-mG2a-f exerted ADCC and complement-dependent cytotoxicity against CHO/HER2 and BT-474 in vitro and exhibited potent antitumor activities in mouse xenograft models. These results indicated that H2Mab-139-mG2a-f exerts antitumor effects against HER2-positive human breast cancers and is useful as an antibody treatment for HER2-positive human cancers.
Ionic Mobility and Charge Carriers Recombination Analyzed in Triple Cation Perovskite Solar Cells
Authors: Rodriguez-Perez Juan Jose , Mhamdi Asya , Torres Jeevan , Montes-Valenzuela Isaac , Rivas Jesus Manuel , Esparza Diego , Contreras-Solorio David Armando
Published: September 2023

In this work, a study of a characterization technique based on open circuit voltage decay is carried out to obtain the recombination resistance of mobile charge carriers and ionic migration in triple cation perovskite solar cells. The devices were fabricated with the structure FTO/TiO2/Cs0.05FA1−XMAXPb(I1−XBrX)3/spiroOMetad/Au. An equivalent circuit, created in Ngspice, was developed adjusting the capacitance and resistance values to fit the experimental open circuit voltage (Voc) decay curves observed. The aim of this study is to associate the perovskite ionic migration with the Voc characteristic time of charge transport in triple cation perovskite solar cells. Thus, an analysis of the open circuit voltage transient behavior was made by taking measurements of the photovoltage as a function of time. The results indicate that the technique shows charge recombination while the device is illuminated. In addition, an enhancement of the recombination resistance when increasing the FA+ concentration was observed. Finally, the transient behavior was associated with MA+, FA+, Cs+ and I− migration, obtaining an ionic mobility in the range between 10−10 to 10−12 cm2 (Vs)−1.
Effectiveness of COVID-19 Vaccination on Transmission: A Systematic Review
Authors: Oordt-Speets Anouk , Spinardi Julia , Mendoza Carlos , Yang Jingyan , Morales Graciela , McLaughlin John M. , Kyaw Moe H.
Published: September 2023

Vaccination against infectious disease affords direct protection from vaccine-induced immunity and additional indirect protection for unvaccinated persons. A systematic review was conducted to estimate the indirect effect of COVID-19 vaccination. From PubMed and Embase, 31 studies were included describing the impact of original wild-type COVID-19 vaccines on disease transmission or viral load. Overall, study results showed the effectiveness of COVID-19 vaccination against SARS-CoV-2 transmission (range 16–95%), regardless of vaccine type or number of doses. The effect was apparent, but less pronounced against omicron (range 24–95% for pre-omicron variants versus 16–31% for omicron). Results from viral load studies were supportive, showing SARS-CoV-2 infections in vaccinated individuals had higher Ct values, suggesting lower viral load, compared to infections among the unvaccinated. Based on these findings, well-timed vaccination programs may help reduce SARS-CoV-2 transmission—even in the omicron era. Whether better-matched vaccines can improve effectiveness against transmission in the omicron era needs further study.
The Role of Sentinel Lymph Node Biopsy in Breast Cancer Patients Who Become Clinically Node-Negative Following Neo-Adjuvant Chemotherapy: A Literature Review
Authors: Ferrarazzo Giulia , Nieri Alberto , Firpo Emma , Rattaro Andrea , Mignone Alessandro , Guasone Flavio , Manzara Augusto , Perniciaro Giuseppe , Spinaci Stefano
Published: September 2023

Background: In clinically node-positive (cN+) breast cancer (BC) patients who become clinically node-negative (cN0) following neoadjuvant chemotherapy (NACT), sentinel lymph node biopsy (SLNB) after lymphatic mapping with lymphoscintigraphy is not widely accepted; therefore, it has become a topic of international debate. Objective: Our literature review aims to evaluate the current use of this surgical practice in a clinical setting and focuses on several studies published in the last six years which have contributed to the assessment of the feasibility and accuracy of this practice, highlighting its importance and oncological safety. We have considered the advantages and disadvantages of this technique compared to other suggested methods and strategies. We also evaluated the role of local irradiation therapy after SLNB and state-of-the-art SLN mapping in patients subjected to NACT. Methods: A comprehensive search of PubMed and Cochrane was conducted. All studies published in English from 2018 to August 2023 were evaluated. Results: Breast units are moving towards a de-escalation of axillary surgery, even in the NACT setting. The effects of these procedures on local irradiation are not very clear. Several studies have evaluated the oncological outcome of SLNB procedures. However, none of the alternative techniques proposed to lower the false negative rate (FNR) of SLNB are significant in terms of prognosis. Conclusions: Based on these results, we can state that lymphatic mapping with SLNB in cN+ BC patients who become clinically node-negative (ycN0) following NACT is a safe procedure, with a good prognosis and low axillary failure rates.
Factors Influencing the Control of Diabetes Measured via Glycated Hemoglobin Concentrations in Adults with Type 1 Diabetes
Authors: Sińska Beata I. , Rzońca Ewa , Kucharska Alicja , Gałązkowski Robert , Traczyk Iwona , Rzońca Patryk
Published: September 2023

Numerous complications of type 1 diabetes (T1D) may be prevented through suitable glycemic control. Glycated hemoglobin (HbA1c) may be one of the markers for the early detection of the metabolic imbalance characteristic of the disease. However, optimal control of diabetes is not achieved in a large group of patients. It was demonstrated that numerous factors (sociodemographic, psychological, and clinical) contributed to this condition. The aim of the study was to identify factors influencing the control of diabetes measured via glycated hemoglobin concentrations in people with T1D. Independent factors influencing better diabetes control measured via HbA1c in the study group included higher disease acceptance, higher nutritional adherence, lower BMI, and a lower risk of eating disorders. Describing the determinants will allow for the improvement of the system of care provided to people with T1D and for it to comprise important psychological variables related to self-care and acceptance of the disease.
Valorisation of Waste Heat in Existing and Future District Heating Systems
Authors: Pakere Ieva , Blumberga Dagnija , Volkova Anna , Lepiksaar Kertu , Zirne Agate
Published: September 2023

To recover thermal energy from different sources, its quality and possibilities for utilisation are essential. The wide range of engineering solutions includes a direct connection to the district heating (DH) system and the integration of low-quality heat using heat pumps to increase the temperature level of recoverable heat. Therefore, this article compares waste heat valorisation strategies for integration into existing DH networks, low-temperature DH, and ultra-low heat supply systems using the multi-criteria assessment method. In addition, a local scale assessment was performed to identify the waste heat role in existing RES-based DH systems. The results show that the highest waste heat valorisation rate could be reached when integrated into low-temperature DH systems due to high waste heat potential and suitable temperature conditions. However, a local scale assessment shows a significant impact on the already implemented solar technologies, as waste heat could cover around 70% of the summer heat load.
Mechanical Ventilation Heat Recovery Modelling for AccuRate Home—A Benchmark Tool for Whole House Energy Rating in Australia
Authors: Sun Jinfei , Ren Zhengen , Guo Jianxiang
Published: September 2023

To manage energy-efficient indoor air quality, mechanical ventilation with a heat recovery system provides an effective measure to remove extra moisture and air contaminants, especially in bathrooms. Previous studies reveal that heat recovery technology can reduce energy consumption, and its calculation needs detailed information on the thermal performance of exhaust air. However, there are few studies on the thermal performance of bathroom exhaust air during and after showers. This study proposed a detailed thermal performance prediction model for bathroom exhaust air based on the coupled heat and mass transfer theory. The proposed model was implemented into the AccuRate Home engine to estimate the thermal performance of residential buildings with heat recovery systems. The time variation of the water film temperature and thickness on the bathroom floor can be estimated by the proposed model, which is helpful in determining whether the water has completely evaporated. Simulation results show that changing the airflow rate in the bathroom has little effect on drying the wet floor without additional heating. The additional air heater installed in the bathroom can improve floor water evaporation efficiency by 24.7% under an airflow rate of 507.6 m3/h. It also demonstrates that heat recovery can significantly decrease the building energy demand with the fresh air load increasing and contribute about 0.6 stars improvement for the houses in Hobart (heating-dominated region). It may be reduced by around 3.3 MJ/(m2·year) for the houses in other regions. With this study, guidelines for optimizing the control strategy of the dehumidification process are put forward.
Book Review: Weedon, G.P.; Chapman, S.D. Ichthyosaurs from the Early Jurassic of Britain; Monograph Series; Siri Scientific Press: Manchester, UK, 2022; ISBN: 978-1-8381528-6-4
Authors: Buffetaut Eric
Published: September 2023

The often beautifully preserved ichthyosaurs from the early Jurassic of Britain occupy a special place in the history of palaeontology [...]
An Estimation of Clayey-Oriented Rock Mass Material Properties, Sited in Koropi, Athens, Greece, through Feed-Forward Neural Networks
Authors: Savvides Ambrosios-Antonios , Antoniou Andreas A. , Papadopoulos Leonidas , Monia Anastasia , Kofina Kalliopi
Published: September 2023

Rock mechanics and the estimation of their material properties through field tests are important aspects and challengees in civil and geotechnical engineering. However, this procedure is expensive and difficult to attain, while the machine learning and neural network theory provide a computational tool for estimating the material properties with limited data. In this work, an estimation of the Young Modulus and the cohesion of a clayey-originated rock through feed-forward neural networks constructed from in situ data measurements is given. The input values come from the Geological Strength Index (GSI) proposed values of the point load index Is50, the uniaxial compression strength σs, as well as the specific gravity γ of the rock mass. The convergence analysis revealed that the convergence occurs at approximately 2000 epochs, with the largest L2 mean square error norm being no greater than 10−5. In addition, it is demonstrated that augmenting γ results in the estimation of rock that is stiffer and stronger. The aforementioned increase in the specific site may be up to 20% for the stiffness and up to 25% for the cohesion. This model, aside from readability and accuracy, offers the convenience of enriching it with more in situ data, thereby enhancing the flexibility of the proposed numerical tool proposed. However, its applicability is limited to the specific data acquired from the particular site, so a more general estimation requires a substantially larger dataset. Finally, the justification of the proposed model has been carried out based on suggestions from the literature for common values of clayey-oriented rock, which is fairly disintegrated as seen in the field.
Imaging of Vascular Graft/Endograft Infection with Radiolabeled White Blood Cell Scan and [18F]FDG PET/CT
Authors: Manta Ringo , Lauri Chiara , Taurino Maurizio , Signore Alberto
Published: September 2023

Diagnosis of vascular graft/endograft infection (VGEI) is a challenge for clinicians due to the heterogeneity of clinical presentation and the complexity of its management. Microbiological culture is the gold standard, but it often fails to isolate the causative microorganism. A non-invasive imaging approach is therefore needed to assess VGEI. CTA is currently the first-choice imaging modality. Nuclear medicine techniques are recommended in case of negative or doubtful CTA results with persisting clinical suspicion. This review aims to summarize data from original studies published in the last decades regarding the role of both white blood cell (WBC) scans and fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ([18F]FDG PET/CT), their respective diagnostic performances, and their integration into the diagnostic approach for patients with a suspicion of VGEI.
The Neglected Remains of the Royal Citadel of Messina, Sicily: A Proposal for a Suitable Conservation and Re-Use Project
Authors: De Pauw Charlotte , Barazzetti Luigi , Vandesande Aziliz , Oteri Annunziata M.
Published: September 2023

Neglected and abandoned heritage sites are a complex research topic, which always requires a thorough understanding of the site’s past and current condition. This article examines how research on history, architecture, and participation can contribute to creating a suitable re-use project for such heritage sites, focusing on a single case study: the Royal Citadel of Messina, Italy. Within the field of history, the city and fortification’s past underscores the importance of the site’s architectural and historical value. An urban analysis and documentation campaign were carried out during the field architecture. The urban analysis focused on the site as a remarkable natural landscape with industrial surroundings. The digital documentation, concentrating on the so-called cistern, emphasized the site’s values. Within a revalorization process, community participation is vital and is, therefore, one of the suggestions to consider in further developments. The last applied method is a comparative case study, namely, the submarine base at Saint-Nazaire, France. Considering the complexity and fragilities of the site, a framework is designed that provides suggestions for the conservation, revalorization, and re-use of the site of the Royal Citadel.
Living by the Sea: Amphibious Landscapes of Identity and Community in a 19th-Century “Fisher’s” Village (Grândola, Portugal)
Authors: Casimiro Tânia M.
Published: September 2023

Mid-19th century maps of Tróia Peninsula (Grândola) indicated the existence of a site named “Fishermen’s huts” on the beach. The site was partially excavated in 2019 and presents the characteristics of a village where around a dozen vernacular architecture shacks accommodated people who lived there between approximately 1860 and 1920. The architecture, material culture, and settlement location reveal the presence of a population with specific social and cultural characteristics related to an amphibious or hybrid lifestyle between the land and the sea. This paper presents this community, considering the relation of the people living there with the surrounding environment (natural and cultural resources) and relations within the community, where it was possible to recognize different genders and identities. These considerations are framed within social, economic, and cultural concepts.
Salicylic Acid Applied via Irrigation Enhances Young Carica papaya L. Plant Performance under Water Deficit
Authors: Mahouachi Jalel , Marcelino-Castro Alexandre D. , Álvarez-Méndez Sergio J. , Urbano-Gálvez Antonio
Published: September 2023

Generally, water deficit induces a negative impact on vegetative growth and physiological and biochemical processes in Carica papaya L. However, the effects of drought magnitude and duration may be dependent on the ability of the genotype to activate mechanisms of defense against the imposed stress. Thus, the purpose of this research was to investigate the effectiveness of adding salicylic acid (SA) to the root system via irrigation against water stress. To assess the morphological and physiological responses of papaya to drought stress, seedlings were exposed to a regulated deficit irrigation system combined with the addition of SA to their irrigation water for 44 days. Results showed that water shortage inhibited papaya growth through the reduction in functional leaf number (27%), fresh (13%) and dry weights (17%), and stem width (9%). Moreover, water scarcity significantly decreased stomatal conductance (48%) and chlorophyll content (21%) and increased proline production (31%). Nevertheless, the exogenous application of SA relieved the effects of water stress on these characteristics, yielding similar values to those from control plants. Therefore, these findings prove the effectiveness of SA applied via irrigation in alleviating papaya damage under water deficit by preserving growth, stomatal conductance, photosynthetic pigments, and proline levels.
Research Progress on the Effect of Nitrogen on Rapeseed between Seed Yield and Oil Content and Its Regulation Mechanism
Authors: Zhu Jiarong , Dai Wenjun , Chen Biyun , Cai Guangqin , Wu Xiaoming , Yan Guixin
Published: September 2023

Rapeseed (Brassica napus L.) is one of the most important oil crops in China. Improving the oil production of rapeseed is an important way to ensure the safety of edible oil in China. Oil production is an important index that reflects the quality of rapeseed and is determined by the oil content and yield. Applying nitrogen is an important way to ensure a strong and stable yield. However, the seed oil content has been shown to be reduced in most rapeseed varieties after nitrogen application. Thus, it is critical to screen elite germplasm resources with stable or improved oil content under high levels of nitrogen, and to investigate the molecular mechanisms of the regulation by nitrogen of oil accumulation. However, few studies on these aspects have been published. In this review, we analyze the effect of nitrogen on the growth and development of rapeseed, including photosynthetic assimilation, substance distribution, and the synthesis of lipids and proteins. In this process, the expression levels of genes related to nitrogen absorption, assimilation, and transport changed after nitrogen application, which enhanced the ability of carbon and nitrogen assimilation and increased biomass, thus leading to a higher yield. After a crop enters the reproductive growth phase, photosynthates in the body are transported to the developing seed for protein and lipid synthesis. However, protein synthesis precedes lipid synthesis, and a large number of photosynthates are consumed during protein synthesis, which weakens lipid synthesis. Moreover, we suggest several research directions, especially for exploring genes involved in lipid and protein accumulation under nitrogen regulation. In this study, we summarize the effects of nitrogen at both the physiological and molecular levels, aiming to reveal the mechanisms of nitrogen regulation in oil accumulation and, thereby, provide a theoretical basis for breeding varieties with a high oil content.
Hyphae of Rhizopus arrhizus and Lichtheimia corymbifera Are More Virulent and Resistant to Antifungal Agents Than Sporangiospores In Vitro and in Galleria mellonella
Authors: Samdavid Thanapaul Rex Jeya Rajkumar , Roberds Ashleigh , Rios Kariana E. , Walsh Thomas J. , Bobrov Alexander G.
Published: September 2023

Mucorales species cause debilitating, life-threatening sinopulmonary diseases in immunocompromised patients and penetrating wounds in trauma victims. Common antifungal agents against mucormycosis have significant toxicity and are often ineffective. To evaluate treatments against mucormycosis, sporangiospores are typically used for in vitro assays and in pre-clinical animal models of pulmonary infections. However, in clinical cases of wound mucormycosis caused by traumatic inoculation, hyphal elements found in soil are likely the form of the inoculated organism. In this study, Galleria mellonella larvae were infected with either sporangiospores or hyphae of Rhizopus arrhizus and Lichtheimia corymbifera. Hyphal infections resulted in greater and more rapid larval lethality than sporangiospores, with an approximate 10–16-fold decrease in LD50 of hyphae for R. arrhizus (p = 0.03) and L. corymbifera (p = 0.001). Liposomal amphotericin B, 10 mg/kg, was ineffective against hyphal infection, while the same dosage was effective against infections produced by sporangiospores. Furthermore, in vitro, antifungal susceptibility studies show that minimum inhibitory concentrations of several antifungal agents against hyphae were higher when compared to those of sporangiospores. These findings support using hyphal elements of Mucorales species for virulence testing and antifungal drug screening in vitro and in G. mellonella for studies of wound mucormycosis.
Properties of Poultry-Manure-Derived Biochar for Peat Substitution in Growing Media
Authors: Wystalska Katarzyna , Malińska Krystyna , Sobik-Szołtysek Jolanta , Dróżdż Danuta , Meers Erik
Published: September 2023

Peat is considered a contentious input in horticulture. Therefore, there is a search for suitable alternatives with similar properties that can be used for partial or complete peat substitution in growing media. Poultry-manure-derived biochar (PMB) is considered such an alternative. This study aimed at determining the properties of PMBs obtained through pyrolysis at selected temperatures and assessing their potentials to substitute peat in growing media based on the selected properties. The scope included the laboratory-scale pyrolysis of poultry manure at the temperatures of 425–725 °C; the determination of selected physico-chemical and physical properties of the obtained biochars, including the contaminants; and the assessment of the potentials of produced biochars to be used as peat substitutes. PMBs contained less than 36% of total organic carbon (TOC). The contents of P and K were about 2.03–3.91% and 2.74–5.13%, respectively. PMBs did not retain N. They can be safely used as the concentrations of heavy metals, polycyclic aromatic hydrocarbons (PAHs), polychlorinatd biphenyls (PCBs), dioxins, and furans are within the permissible values (except for Cr). Due to high pH (9.24–12.35), they can have a liming effect. High water holding capacity (WHC) in the range of 158–232% w/w could allow for the maintenance of moisture in the growing media. PMBs obtained at 525 °C, 625 °C, and 725 °C showed required stability (H/Corg < 0.7).
Vibrotactile Feedback for a Person with Transradial Amputation and Visual Loss: A Case Report
Authors: Peternell Gerfried , Penasso Harald , Luttenberger Henriette , Ronacher Hildegard , Schlintner Roman , Ashcraft Kara , Gardetto Alexander , Ernst Jennifer , Kropiunig Ursula
Published: September 2023

Background and Objectives: After major upper-limb amputation, people face challenges due to losing tactile information and gripping function in their hands. While vision can confirm the success of an action, relying on it diverts attention from other sensations and tasks. This case report presents a 30-year-old man with traumatic, complete vision loss and transradial left forearm amputation. It emphasizes the importance of restoring tactile abilities when visual compensation is impossible. Materials and Methods: A prototype tactile feedback add-on system was developed, consisting of a sensor glove and upper arm cuff with related vibration actuators. Results: We found a 66% improvement in the Box and Blocks test and an overall functional score increase from 30% to 43% in the Southampton Hand Assessment Procedure with feedback. Qualitative improvements in bimanual activities, ergonomics, and reduced reliance on the unaffected hand were observed. Incorporating the tactile feedback system improved the precision of grasping and the utility of the myoelectric hand prosthesis, freeing the unaffected hand for other tasks. Conclusions: This case demonstrated improvements in prosthetic hand utility achieved by restoring peripheral sensitivity while excluding the possibility of visual compensation. Restoring tactile information from the hand and fingers could benefit individuals with impaired vision and somatosensation, improving acceptance, embodiment, social integration, and pain management.
Hyperbaric Oxygen Therapy Counters Oxidative Stress/Inflammation-Driven Symptoms in Long COVID-19 Patients: Preliminary Outcomes
Authors: Mrakic-Sposta Simona , Vezzoli Alessandra , Garetto Giacomo , Paganini Matteo , Camporesi Enrico , Giacon Tommaso Antonio , Dellanoce Cinzia , Agrimi Jacopo , Bosco Gerardo
Published: September 2023

Long COVID-19 patients show systemic inflammation and persistent symptoms such as fatigue and malaise, profoundly affecting their quality of life. Since improving oxygenation can oppose inflammation at multiple tissue levels, we hypothesized that hyperbaric oxygen therapy (HBOT) could arrest inflammation progression and thus relieve symptoms of COVID-19. We evaluated oxy-inflammation biomarkers in long COVID-19 subjects treated with HBOT and monitored with non-invasive methods. Five subjects (two athletes and three patients with other comorbidities) were assigned to receive HBOT: 100% inspired O2 at 2.4 ATA in a multiplace hyperbaric chamber for 90 min (three athletes: 15 HBOT × 5 days/wk for 3 weeks; two patients affected by Idiopathic Sudden Sensorineural Hearing Loss: 30 HBOT × 5 days/wk for 6 weeks; and one patient with osteomyelitis: 30 HBOT × 5 days/wk for week for 6 weeks and, after a 30-day break, followed by a second cycle of 20 HBOT). Using saliva and/or urine samples, reactive oxygen species (ROS), antioxidant capacity, cytokines, lipids peroxidation, DNA damage, and renal status were assessed at T1_pre (basal level) and at T2_pre (basal level after treatment), and the results showed attenuated ROS production, lipid peroxidation, DNA damage, NO metabolites, and inflammation biomarker levels, especially in the athletes post-treatment. Thus, HBOT may represent an alternative non-invasive method for treating long COVID-19-induced long-lasting manifestations of oxy-inflammation.
Enhanced Electricity Generation and Heavy Metal Removal by a Rutile–Biochar Cathode MFC
Authors: Zhou Jiqiang , Wang Lei , Wang Zhe , Feng Yonglin , Luo Guangfeng , Wang Zhiyang , Wu Jing , Hu Peiqing
Published: September 2023

The issue of heavy metal pollution has gradually emerged as a significant global concern. Microbial fuel cells (MFCs) hold immense potential for clean energy production and pollutant treatment. However, their limited power generation efficiency hampers the large-scale implementation of MFCs. The porous microstructure of biochar and the excellent physical and chemical properties of rutile render both materials promising catalysts with positive potential. In this study, we employed biochar as a carrier for rutile to fabricate a novel rutile–biochar (Rut-B) composite material, investigating its efficacy in enhancing MFC power generation efficiency as a cathode catalyst, as well as its application in heavy metal pollutant degradation. Scanning electron microscopy (SEM) results confirmed the successful preparation of biochar-loaded rutile composites. The MFC achieved maximum current density and power density values of 152.26 mA/m2 and 9.88 mW/m2, respectively—an increase of 102.7% and 224% compared to the control group without the addition of Rut-B. Furthermore, the biochar-loaded rutile MFC exhibited excellent performance in degrading heavy metal pollutants; within 7 h, the Pb2+ degradation rate reached 92.4%, while the Zn2+ degradation rate reached 84%. These rates were significantly higher than those observed in the control group, by factors of 437.2% and 345%, respectively. The cyclic degradation experiments also demonstrated the outstanding stability of the system over multiple cycles. In summary, this study successfully combined natural rutile with biochar to create an efficient electrode catalyst that not only enhances electricity generation performance but also provides an environmentally friendly and cost-effective approach for remediating heavy metal pollution.
An Investigation into the Performance and Mechanisms of Soymilk-Sized Handmade Xuan Paper at Different Concentrations of Soymilk
Authors: Wu Chunfang , Liu Yangyang , Hu Yanxiao , Ding Ming , Cui Xiang , Liu Yixin , Liu Peng , Zhang Hongbin , Yang Yuliang , Zhang Hongdong
Published: September 2023

Invaluable paper relics that embody a rich traditional culture have suffered damage, requiring urgent restoration. In this context, the utilization of soymilk as a sizing agent holds great significance and reverence. This study investigates the use of soymilk as a sizing agent for Xuan paper and evaluates its effects on various properties and the long-term behavior of the paper. The findings reveal that the application of soymilk as a sizing agent for Xuan paper imparts distinct properties, including hydrophobicity, improved mechanical properties, and unique chromaticity. These characteristics—arising from the papillae on the surface of the Xuan paper, the protein folding of the soy protein, and hydrogen-bonding interactions between the soy protein and paper fibers—play a crucial role in shaping the paper’s unique attributes. From a physicochemical perspective, the aging process leads to multiple changes in paper properties. These changes include acidification, which refers to a decrease in pH, as well as a decline in mechanical strength, an increase in chromaticity, and a decrease in the degree of polymerization (DP) of the paper. The Ekenstam equation is employed to predict the lifespan of the paper, showing longer lifespans for Sheng Xuan paper and a negative correlation between soymilk concentration and lifespan in soymilk-sized paper. Our work provides valuable insights for the preservation and maintenance of paper, highlighting the potential benefits and challenges of using soymilk for surface sizing.
Weight Loss and Competition Weight Comparing Male and Female Mixed Martial Artists Competing in the Ultimate Fighting Championship’s (UFC) Flyweight Division
Authors: Peacock Corey A. , Braun Justin , Sanders Gabriel J. , Ricci Anthony , Stull Charles , French Duncan , Evans Cassandra , Antonio Jose
Published: September 2023

Background: Although there is much literature demonstrating weight changes in professional mixed martial arts (MMA) athletes, there is minimal data comparing male and female MMA athletes. Therefore, the purpose of the current study was to compare weight changes between professional male and female MMA athletes leading up to competition. Methods: One hundred and three professional flyweight MMA athletes competing for the Ultimate Fighting Championship (UFC) were used for the study. Weight was obtained at multiple time points leading up to the competition. Two-way ANOVAs and post hoc t-tests were used, and significance was set at p ≤ 0.05. Results: ANOVA revealed there was a significant main effect of condition for weight changes (p < 0.001) and a significant main effect of sex on weight changes (p = 0.002) prior to competition. Post hoc analysis revealed that males lost more weight prior to the official weigh-in and gained more weight prior to competition when compared to females (p ≤ 0.05). Conclusion: MMA athletes lose weight prior to the official weigh-in and gain weight prior to competition. Moreover, male MMA athletes lose more weight prior to and gain more weight after when compared to female MMA athletes competing in the UFC’s flyweight division.
Integrating Agricultural and Ecotourism Development: A Crop Cultivation Suitability Framework Considering Tourists’ Landscape Preferences in Qinghai Province, China
Authors: Wang Huihui , Zhan Jinyan , Wang Chao , Blinov Oleg Anatolyevich , Asiedu Kumi Michael , Liu Wei , Chu Xi , Teng Yanmin , Liu Huizi , Yang Zheng , Bai Chunyue
Published: September 2023

Ecotourism and agricultural development have been proven to have synergistic effects, although few studies have employed a spatial planning approach to incorporate tourism growth into crop cultivation planning. This study constructed a theoretical framework of environmental suitability—farmland accessibility—tourist’s landscape preferences for crop cultivation planning to link regional agriculture and ecotourism development. The spatial planning of rapeseed cultivation in Qinghai Province was chosen as a case study. The main research methods include an environmental suitability analysis based on remote sensing and Maxent modeling, a farmland accessibility analysis based on a GIS platform, and a landscape preference questionnaire survey of tourists. According to the survey’s findings, almost 80% of tourists thought rapeseed flowers enhanced the beauty of natural landscapes. This demonstrated the enormous potential of rapeseed fields for fostering ecotourism. Based on environmental factors, the optimum region for rapeseed cultivation covered 5.38% of the study area, or roughly 6327 km2. The comprehensive optimum zone, which encompassed both agricultural accessibility and environmental suitability, was equal to 12.63% of the study area’s farming area, or around 929 km2. This study’s crop cultivation suitability framework can integrate agricultural and ecotourism development, with substantial implications for achieving coordinated economic, social, and environmental development.
Resource Allocation for Secure MIMO-SWIPT Systems in the Presence of Multi-Antenna Eavesdropper in Vehicular Networks
Authors: Ganapathy Vieeralingaam , Ramachandran Ramanathan , Ohtsuki Tomoaki
Published: September 2023

In this paper, we optimize the secrecy capacity of the legitimate user under resource allocation and security constraints for a multi-antenna environment for the simultaneous transmission of wireless information and power in a dynamic downlink scenario. We study the relationship between secrecy capacity and harvested energy in a power-splitting configuration for a nonlinear energy-harvesting model under co-located conditions. The capacity maximization problem is formulated for the vehicle-to-vehicle communication scenario. The formulated problem is non-convex NP-hard, so we reformulate it into a convex form using a divide-and-conquer approach. We obtain the optimal transmit power matrix and power-splitting ratio values that guarantee positive values of the secrecy capacity. We analyze different vehicle-to-vehicle communication settings to validate the differentiation of the proposed algorithm in maintaining both reliability and security. We also substantiate the effectiveness of the proposed approach by analyzing the trade-offs between secrecy capacity and harvested energy.
Improved RSSI Indoor Localization in IoT Systems with Machine Learning Algorithms
Authors: Maduranga Madduma Wellalage Pasan , Tilwari Valmik , Abeysekera Ruvan
Published: September 2023

Recent developments in machine learning algorithms are playing a significant role in wireless communication and Internet of Things (IoT) systems. Location-based Internet of Things services (LBIoTS) are considered one of the primary applications among those IoT applications. The key information involved in LBIoTS is finding an object’s geographical location. The Global Positioning System (GPS) technique does not perform better in indoor environments due to multipath. Numerous methods have been investigated for indoor localization scenarios. However, the precise location estimation of a moving object in such an application is challenging due to the high signal fluctuations. Therefore, this paper presents machine learning algorithms to estimate the object’s location based on the Received Signal Strength Indicator (RSSI) values collected through Bluetooth low-energy (BLE)-based nodes. In this experiment, we utilize a publicly available RSSI dataset. The RSSI data are collected from different BLE ibeacon nodes installed in a complex indoor environment with labels. Then, the RSSI data are linearized using the weighted least-squares method and filtered using moving average filters. Moreover, machine learning algorithms are used for training and testing the dataset to estimate the precise location of the objects. All the proposed algorithms were tested and evaluated under their different hyperparameters. The tested models provided approximately 85% accuracy for KNN, 84% for SVM and 76% accuracy in FFNN.
Abscisic Acid: Metabolism, Signaling, and Crosstalk with Other Phytohormones under Heavy Metal Stress
Authors: Bano Ambreen , Singh Kratika , Singh Surendra Pratap , Sharma Pooja
Published: September 2023

Heavy metal (HM) stress poses a global risk to crops, ecological systems, and human health. It disrupts cellular ionic equilibrium, cell membrane integrity, metabolic balance, and the activities of enzymes and proteins, severely impacting physiological processes, plant development, and agricultural productivity. Although plants naturally activate defense mechanisms to mitigate the adverse effects of HM stress, they cannot completely prevent them. Phytohormones counter HM toxicity, aiding growth. External application and internal regulation via signaling/biosynthesis genes offer defense against HM-induced damage. A pivotal signaling molecule in plant adaptive responses to environmental stressors, including HM toxicity, is abscisic acid (ABA). Despite ABA’s role in abiotic stress responses such as drought and salinity, its function and crosstalk with other phytohormones under HM stress remain poorly understood. Nonetheless, exogenously applied ABA serves as a strategic approach to enhancing plants’ resistance to HM toxicity by promoting osmolyte accumulation and reinforcing antioxidant activity. ABA significantly regulates various plant growth and metabolic activities under diverse environmental conditions. This review highlights the effects of HM stress on plants and explores ABA involvement in production, signaling, catabolism, and transport within plant tissues. The purpose of this paper is to shed light on the complex interplay between the metabolism of ABA, its signaling, and its interactions with other phytohormones (e.g., auxins, gibberellins, and ethylene) during HM exposure. Furthermore, we delve into the function of ABA to mitigate HM stress and elucidate its interactions with other phytohormones.
Threshold Effect of Manufacturing Agglomeration on Eco-Efficiency in the Yellow River Basin of China
Authors: Wang Chuanhui , Han Asong , Gong Weifeng , Zhao Mengzhen , Li Wenwen
Published: September 2023

Research on the impact of industrial development on the ecological environment of the Yellow River Basin plays a significant role in accelerating the high-quality development of that key region of China. Since the impact of industrial agglomeration on eco-efficiency is very complex, this study constructs a panel threshold model of the impact of manufacturing agglomeration on eco-efficiency and analyzes the heterogeneity of different industries. The results led to the following conclusions: The optimal range for the industrial agglomeration level is 0.37 to 0.40. When the industrial agglomeration level is in that optimal range, the manufacturing agglomeration has a significant positive effect on eco-efficiency, and the eco-efficiency level increases by 2.87% for every 1% increase in the agglomeration level. The agglomeration of high-energy-consuming manufacturing has obvious negative externalities for eco-efficiency; however, this negative effect weakens after the threshold value is reached. However, the impact of the agglomeration of low- and medium-energy-consuming manufacturing industries on eco-efficiency is manifested as a significant positive effect, though when the agglomeration degree is low, the effect is not significant.
Single-Photon Superradiance and Subradiance as Collective Emission from Symmetric and Anti-Symmetric States
Authors: Piovella Nicola , Olivares Stefano
Published: September 2023

Recent works have shown that collective single-photon spontaneous emission from an ensemble of N resonant two-level atoms is a rich field of study. Superradiance describes the emission from a completely symmetric state of N atoms, with a single excited atom prepared with a given phase, for instance, imprinted by an external laser. Instead, subradiance is associated with the emission from the remaining N−1 asymmetric states, with a collective decay rate less than the single-atom value. Here, we discuss the properties of the orthonormal basis of symmetric and asymmetric states and the entanglement properties of superradiant and subradiant states. On the one hand, by separating the symmetric superradiant state from the subradiant ones, we are able to determine the subradiant fraction induced in the system by the laser. On the other hand, we show that, as the external laser is switched off and the atomic excitation decays, entanglement in the atomic ensemble appears when the superradiant fraction falls below the threshold 1/N.
Singularities of Scattering Matrices
Authors: Schwarz Albert
Published: September 2023

Our main result is the analysis of singularities of the integrands of integrals representing the matrix elements of the scattering matrix and the inclusive scattering matrix in perturbation theory. These results are proven for any quantum field theory in any dimension.
Upper-Layer Bacterioplankton Potentially Impact the Annual Variation and Carbon Cycling of the Bathypelagic Communities in the South China Sea
Authors: Liu Xiuping , Li Jiaqian , Ding Xueyan , Sen Kalyani , He Yaodong , Bai Mohan , Wang Guangyi
Published: September 2023

Pelagic bacterioplankton exhibit biogeographical patterns linked with exporting organic carbon and energy fluxes into the deep ocean. However, knowledge of the mechanisms shaping deep-sea bacterial communities remains largely elusive. In this study, we used high throughput sequencing of the 16S rRNA gene to reveal significant annual bacterioplankton community dynamics in the South China Sea during three summer cruises (2016–2018). As we expected, the epipelagic–bathypelagic connective amplicon sequence variants (ASVs, mostly belonging to Actinobacteriota, Firmicutes, and Cyanobacteria) suggested that they not only affect the community structure but also influence the carbon cycling functions of bathypelagic bacterioplankton in different years. However, the microbial source tracking (MST) analysis indicated that the directly linked proportions between the bathypelagic and epipelagic samples were minimal. Thus, the epipelagic bacteria communities may form “seeds” rather than directly sinking into the deep ocean to influence bathypelagic bacteria. This study provides a new perspective on the mechanisms shaping the deep ocean bacterioplankton communities.