bluuebunny/crossref_metadata_2025 huggingface dataset:
Manajemen Hubungan Masyarakat untuk Meningkatkan Citra Pendidikan Tinggi Terbuka dan Jarak Jauh Melalui Media Sosial di Universitas Terbuka
Authors: Suteki Mega
Published: April 2021

Latar belakang penelitian ini adalah munculnya metode hubungan masyarakat baru melalui media sosial di dunia pendidikan. Tujuan penelitian ini adalah untuk mendeskripsikan dan menganalisis manajemen hubungan masyarakat dalam meningkatkan citra pendidikan tinggi terbuka dan jarak jauh melalui media sosial di Universitas Terbuka; dan mendeskripsikan serta menganalisis faktor yang menghambat manajemen hubungan masyarakat dalam meningkatkan citra pendidikan tinggi terbuka dan jarak jauh melalui media sosial di Universitas Terbuka. Metode penelitian yang digunakan adalah metode kualitatif. Metode ini digunakan untuk menghasilkan hasil data deskriptif. Teknik pengumpulan data menggunakan wawancara, dan dokumen serta menggunakan analisa data kualitatif model interaktif Miles, Hubberman dan Saldana. Hasil temuan di lapangan menunjukkan bahwa perencanaan kegiatan hubungan masyarakat di UPBJJ-UT dibuat berdasarkan pedoman yang dibuat di Universitas Terbuka pusat. Pengorganisasian kegiatan hubungan masyarakat di UPBJJ-UT Surabaya mencakup pengaturan anggota staf dalam mengelola akun media sosial dan website; Koordinasi mencakup pengaturan struktur staf dan pendelegasian kerja; Komunikasi dilakukan secara internal dan eksternal; Pelaksanaan program dibagi menjadi program rutin dan program insidental; Pengawasan dilakukan oleh koordinator dan Kepala UPBJJ-UT Surabaya; Fungsi modifikasi dilaksanakan melalui rapat evaluasi; Hambatan internal berupa penguasaan teknologi informasi mahasiswa yang beragam dan beban kerja staf yang berat. Sedangkan hambatan eksternal adalah infrastruktur jaringan internet.
Indonesia Government Public Communication in the Covid-19 Pandemic Handling
Authors: Sahlan Muhammad
Published: April 2021

Since Covid-19 broke out in Indonesia, the public has monitored various government policies in dealing with these health disasters. However, policies run slowly; it gives rise to diverse public opinion. These multiple opinions become a form of communication between the government and society. However, the government does not fully capture peopleâ€™s views, so people feel they do not receive government policiesâ€™ feedback. The purpose of this research is to find out how the Indonesian governmentâ€™s public communication is in dealing with the Covid-19 pandemic. The research used a descriptive qualitative method using data during Covid-19. This study explains how the debate of government and community communication occurs in the form of public opinion. Various forms of public opinion from adverse to positive states become message instruments aimed at the government. This instrument then forms communication in the form of action as a sense of moral panic due to the absence of a back answer to the opinion expressed. So, these opinions are only as answers and realized by society in phenomena.
Procedural world nonlinear dynamics
Authors:   Kuzbass state technical university named after T.F. Gorbachev, Russia Kuzbass state agricultural academy, Ravochkin N.N.
Published: April 2021

In this article, the author attempts to uncover and then critically analyze the nonlinear world dynamics of the leading trend of our time. Close attention is paid to the place and role of social processes that contribute to the growth of nonlinearity and unpredictability of modern world dynamics. The meaning of the synergetic concept is clarified when considering the dynamics of the present world. Shows the variability of modern social relations. The essence of the self-determinability of the world is presented. The hierarchization of modern social systems is determined.
The “Dual Sources Account,” Predestination, and the Problem of Hell
Authors: Wood Adam Noel
Published: April 2021

W. Matthews Grant's "Dual Sources Account" aims at explaining how God causes all creaturely actions while leaving them free in a robust libertarian sense. It includes an account of predestination that is supposed to allow for the possibility that some created persons ultimately spend eternity in hell. I argue here that the resources Grant provides for understanding why God might permit created persons to end up in hell are, for two different reasons, insufficient. I then provide possible solutions to these two problems, compatible with Grant's account overall, that help show why God might allow hell.
Publicaciones científicas de países latinoamericanos sobre educación ante el COVID-19. Revisión sistemática de la literatura
Authors: Perdomo de Flores Bexi
Published: April 2021

La presente revisión sistemática de la literatura se realizó con el objetivo de describir la producción científica de países latinoamericanos en materia de Educación en tiempos de la pandemia por COVID-19 publicados en SciELO. Se establecieron criterios de búsqueda y de inclusión para asegurarse que la evidencia a analizar realmente respondiera al objetivo planteado, eliminando así posibles sesgos. En la búsqueda inicial se obtuvieron 85 resultados. Luego, se dio inicio al proceso de cribado, siguiendo estrictamente los protocolos correspondientes para obtener la evidencia analizable (n=14). Se hizo un análisis cuantitativo para la caracterización bibliométrica de la evidencia. En segundo lugar, se hizo el análisis cualitativo del contenido para detectar las categorías en función de los patrones observados en los artículos. El análisis cuantitativo mostró las tendencias en tipo de estudio, país e idioma, destacando Brasil en cantidad de publicaciones. 50% de los artículos estaban publicados en revistas indexadas en Scopus. El análisis cualitativo permitió identificar dos categorías: enseñanza (la cual presentó dos subcategorías) y gestión. Se concluye que la producción científica es baja y que es preciso ampliar en número y variables de estudio para poder documentar la experiencia latinoamericana en educación ante la pandemia.
Estado de preparación de los docentes en ambientes virtuales de aprendizaje en tiempos de COVID-19
Authors: Rojas Hernández Yoisel Leopoldo , González Méndez Adrián
Published: April 2021

Constituye una necesidad el fortalecimiento de la formación continua del docente universitario orientada a los Ambientes Virtuales de Aprendizaje (AVA), como vía para dar solución a la continuidad del curso académico en tiempos de COVID-19. El objetivo es diagnosticar el estado de la preparación de los docentes, en temas relacionados con los AVA. Se realizó un estudio exploratorio en la Universidad de Ciencias Médicas de Sancti Spíritus durante los años 2020 y 2021, empleando los métodos teóricos, empíricos y estadísticos-matemáticos respectivos. El estudio teórico y la exploración empírica permitió identificar información legal que apoya la formación continua, ausencia de actividades formativas en AVA, corroborándose la inexistencia de un proceso de formación continua orientado a capacitar a los docentes, siendo insuficiente el uso de la plataforma virtual, las actividades metodológicas que promuevan el uso de los AVA, las competencias del docente y la comprobación de la preparación de los profesores en AVA. Se concluye que resultan insuficientes las acciones formativas en AVA, la percepción de la necesidad de uso, la utilización en la práctica pedagógica y la cultura tecnológica en los docentes, lo cual pone en riesgo la ejecución del curso académico asistido por los AVA, en tiempos de COVID-19.
Aprender en la virtualidad
Authors: Aveleyra Ema Elena , Rossi Sergio David
Published: April 2021

Se presentan los resultados obtenidos de la aplicación de la modalidad a distancia en una asignatura de física correspondiente a la Facultad de Ingeniería de la Universidad de Buenos Aires. La técnica usada fue la encuesta realizada sobre 1164 estudiantes de segundo año de las carreras de ingeniería, luego de haber finalizado la cursada correspondiente al primer cuatrimestre de 2020. Del análisis cuanti-cualitativo, llevado a cabo, se obtienen resultados positivos de la implementación de la modalidad. Los comentarios vertidos por los estudiantes, que completan las respuestas a las preguntas realizadas, justifican abordar algunos cambios metodológicos y la búsqueda de facilitadores para la interacción entre estudiantes y estudiantes-docentes.
Translation Aspect of Analyzing and Sayings (on Macedonian and Russian texts)
Authors:   Military University, Stepanenko Elena
Published: April 2021

The article deals with proverbs translational aspects and sayings in Macedonian and Russian texts. It also provides modern subjects matters of Macedonian-Russian lexicography and analyses the translational techniques in bilingual dictionaries and the interpreters’ and translators’ practice.
Marking Ends of Sentences in Middle of the 17th centuryʼs Church Slavonic Text
Authors:   Lomonosov Moscow State University, Nikolenkova Natalia
Published: April 2021

The article deals with the punctuation of Church Slavonic texts in the mid-17th century and the process of forming a sentence as a unit of written text that begins at this time. First of all, it is shown that the rules for the marking sentence boundary are described in the Grammar of 1648: this is the use of the dot sign and the use of a capital letter after it. Examining the translation of Blau’s Atlas made in the second half of the 50s in Moscow, we find that both the translators and the scribes of the whitewash copies sought to comply with these new norms. The result of the activity of the scribes influenced the punctuation of Church Slavonic printed books of the second half of the 17th century.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KUALITAS HIDUP PASIEN DIABETES MELITUS TIPE 2
Authors: Suwanti Erna , Andarmoyo Sulistyo , Purwanti Lina Ema
Published: April 2021

Diabetes Melitus merupakan penyakit kronis yang memerlukan terapi dan perawatan jangka panjang bahkan menyertai seumur hidup penderita. Berbagai komplikasi dapat terjadi bila kadar gula darah tidak terkontrol dengan baik. Dari komplikasi yang terjadi akan berdampak pada kualitas hidup penderita. Dukungan keluarga sangat diperlukan  bagi kelangsungan hidup penderita Diabetes Melitus, sehingga dengan dukungan keluarga yang baik diharapkan penderita Diabetes Melitus mempunyai kualitas hidup yang baik pula. Penelitian ini bertujuan untuk mengetahui hubungan dukungan keluarga dengan kualitas hidup pasien Diabetes Melitus tipe 2 di poli rawat jalan Rumah Sakit Islam Siti Aisyah Madiun. Penelitian ini merupakan penelitian deskriptif analitik dengan pendekatan cross-sectional. Teknik sampling yang digunakan  purposive sampling.  Sampel yang digunakan sejumlah 86 responden yang merupakan pasien Diabetes Mellitus tipe 2 yang berkunjung di poli penyakit dalam Rumah Sakit Islam Siti Aisyah Madiun. Instrumen penelitian menggunakan 3 kuisioner, yakni kuisioner demografi responden, kuisioner dukungsn keluarga dan kuisioner DQOL (Diabetes Quality Of Life). Analisis hipotesis menggunakan uji chi-square. Hasil penelitian menunjukkan bahwa ada hubungan dukungan keluarga dengan kualitas hidup pasien Diabetes Melitus tipe 2 di poli penyakit dalam Rumah Sakit Islam Siti Aisyah Madiun dengan p value = 0.000 (<0,05) dan nilai keeratan hubungan cukup kuat (0,463). Kesimpulan dari penelitian ini adalah dukungan keluarga dalam bentuk dukungan penghargaan, emosional, instrumental, dan informasi sangat penting dalam membantu meningkatkan kualitas hidup pasien Diabetes Melitus tipe 2 di poli penyakit dalam Rumah Sakit Islam Siti Aisyah Madiun.
Karakteristrik Enkapsulat Pewarna dari Ekstrak Daun Pepaya (Carica papaya L.) pada Perlakuan Perbandingan Gelatin dan Maltodekstrin
Authors: Aditya Samapta Manggala , Wrasiati Luh Putu , Mulyani Sri
Published: April 2021

Papaya leaves can be used as a green dye because it contains chlorophyll. Chlorophyll compounds as a green coloring are obtained by extraction and stored in the form of encapsulation powder. This study has two purposes, (i) to know the effect of the gelatin and maltodextrin encapsulants ratio on the encapsulates characteristics of papaya leaf coloring extract, and (ii) to determine the encapsulates comparison treatment of the best gelatin and maltodextrin in producing the characteristic encapsulate extract of papaya leaf coloring. Experiments in this study were  using a randomized block design with one  treatment, namely the ratio of gelatin and maltodextrin consisting of 7 levels, namely, (1:0), (0:1) (1:1), (1:1.5), (1:2), (1:2.5), (1:3). The results showed that the ratio of gelatin-maltodextrin was highly significant (P<0.05) on yield, total chlorophyll content, solubility, brightness level, redness level (a*), yellowish level (b*) and no effect (P>0.05) on water content. The treatment of gelatin and maltodextrin (1:3) ratio was the best treatment to produce encapsulate sea lettuce extract with yield of 35.27 %, water content of 6.13%, total chlorophyll content of 1192.69 ppm, solubility of 79.12%, brightness level (L*) 39.39, redness level (a*) 16.95 and yellowish level (b*) 14.84.

Keywords : papaya leaf extract, gelatin, maltodextrin, encapsulation
Analisis Perencanaan Sumber Daya Manusia di PT Aerofood Acs Unit Denpasar
Authors: Ruth Sangiang , Satriawan I Ketut , Sadyasmara Cokorda Anom Bayu
Published: April 2021

The role of human resource management is the main key of transformation the management of a company to gain a competitive advantage. The purposes of this research were to analyze the condition and the demand and supply of human resources for the next two years at PT Aerofood ACS Denpasar unit. The methods used to analyze human resource demand data were Trend Analysis and Delphi technique along with the inventory skill to analyze the human resource supply data. Trend analysis method used to increases the demand for human resource for the next two years, while the Delphi technique used to sees the condition of the company for the last 4 years. The inventory skill method used to analyze the offering position for internal and external employees for the next two years. The condition of human resource in the company during for the latest year is good, because the percentage of employee turnover is 0.57 percent and the employee retention rate is 99.43 percent. The percentage of absence level for back office employees was only 7.07 percent and 8.46 percent for operational employees. The projection result of human resource demands for the next two years, there will be a reduction in the number of permanent workers by 17 people in the first year and a further reduction of 34 employees in the second year, this is due to the absence of permanent employment designation for the last four years. The contract employees have decreased 17 employees at the first year due to force majeure and an increase of 55 people in the second year when the amount of production is normal, especially for operational workforce. Outsourcing labor and daily workers are not needed in the first year but will likely be needed further.

Keywords: Aerofood ACS, human resource, trend analysis, Delphi technique, skill inventory
Dysregulation of Micro RNA-155 as a Biomarker in Iraqi Patients with Prostate Cancer
Authors: Al-saffar Jinan MJ
Published: April 2021

Chronic inflammation can induce proliferative events and posttranslational DNA modifications in prostate tissues through oxidative stress. The miR-155 expression is abnormally increased in tumors. Therefore, this study aims to explore the clinical significance of serum TNF-α and IL-1α as well as miR-155 expression in prostate cancer (PC) patients.

A total of 50 blood samples from patients diagnosed with prostate cancer were collected from the Oncology Department, Baghdad Teaching Hospital, along with samples from 50 healthy volunteers. Serum TNF-α and IL-1α levels in Iraqi males with prostate cancer were estimated by using enzyme-linked immunosorbent

assay (ELISA). The total RNA was extracted from all subjects and converted to cDNA using Stem-Loop technique and the expression was measured by real-time PCR (RT-PCR) using SYBR Green with specific primers. The results showed that serum TNF-α and IL-1α levels were significantly higher in the clinical stage of tumor node metastasis (TNM) as compared to those in the control (p<0.05). The miR- 155 level was significantly elevated in the patients  compared with the control (p<0.05), being positively correlated with advanced stages. It is concluded that circulating miR-155 could act as a promising marker for the diagnosis and prognosis of PC.
Developing a supportive peer environment: Engaging students through cooperative skills in the classroom
Authors:   Pepperdine University, 24255 Pacific Coast Highway, Malibu, CA 90263, USA, Saroyan John S.
Published: April 2021

Children with peer acceptance problems struggle to fit in among classmates and often feel rejection and social isolation. Common reasons can stem from a child’s unique personality, individuality or special needs issues. These children often experience emotional problems and symptoms resulting from poor social relationships and difficulty fitting in to their environment. Within the classroom, teachers may provide encouragement and support for these children as well as their better adjusted peers, helping them equally engage through improved understanding and acceptance. In this article, a cooperative classroom approach is discussed to help students develop healthier communication with mutual respect and the freedom to be their natural, core self. A Democratic Student Council is presented as a cooperative classroom activity that encourages peer compassion and openness while supporting individuality and feelings of belonging.
Konflik Keagenan dalam Perspektif Keuangan Keperilakuan
Authors: Giovanni Axel , Utami Devi Wahyu , Astuti Umi Dwi , Fania Fania
Published: April 2021

Penelitian ini bertujuan untuk memberikan tinjauan teoritis mengenai keterkaitan mental accounting, overconfidence dan konflik keagenan. Konflik keagenan dapat dipicu karena pihak manajemen sebagai agent tidak bertindak sesuai dengan kepentingan pemilik perusahaan. Konflik keagenan dapat dijelaskan melalui perspektif keuangan keperilakuan yakni mental accounting dan overconfidence. Ditinjau dari aspek mental accounting, investor dimungkinkan menunjukkan perilaku yang berbeda pada setiap post atau account. Dalam konteks pendapatan berupa dividen, pemegang saham mengelompokkan dividen sebagai bagian dari akun current income, maka pemegang saham menghendaki dividen dalam besaran atau jumlah yang signifikan serta dibayarkan secara rutin. Sementara, pihak manajemen sebagai agent yang mengasumsikan memiliki informasi lebih akan mengutamakan current income digunakan sebagai sumber pembiayaan internal sesuai dengan perpektif pecking order theory. Dalam perspektif overconfidence, konflik agensi dipicu karena kecenderungan manajemen perusahaan memberikan nilai yang berlebihan atas kemampuannya dalam mencapai tujuan sehingga mengesampingkan probabilitas terjadinya resiko.
SPELLING NORM AS SACRED PHENOMENON
Authors:   KSPU named after V.P. Astafiev, Vasilyev A.D.
Published: April 2021

Statement of the problem. The norm is an extremely important category that serves to regulate the diverse activities of society. With the help of ideas about the norm, an axiological scale is formed. Depending on the fundamental circumstances this scale is subject to remarking: the sacred and the profane change places. This also applies to issues of language policy, most clearly found in the field of spelling. It is in establishing uniform rules of spelling and punctuation that the state manifests its will in the most visible way. The purpose of the article is sociolinguistic analysis of spelling reforms and their results. Research methodology. Sociolinguistic analysis involves the analysis of language phenomena on the basis of the stated concept in specific historical and social conditions, as well as taking into account social, psychological, and linguistic characteristics of the audience to which they are aimed. The results of the study. The history of the Russian language knows cases of radical spelling reforms. However, the most famous of them (1917), when spelling was drastically simplified to facilitate its mastering by people at large, entailed very negative psychosocial ramifications, in effect, a sharply contemptuous disregard of rules. The most recent example of the project for the Russian spelling reform in the 21 st century was developed in 2007, but did not receive official approval. Conclusions. Russian should be strictly regulated in accordance with the existing rules of the Russian written language, based on the sacred status of the Russian language as one of the key symbols of the state. It is also advisable to regularly publish constantly updated spelling dictionaries after their mandatory official approval.
ON TEACHING A COURSE IN TRANSLATION STUDIES (ON THE EXAMPLE OF THE FOREIGN LANGUAGES DEPARTMENT AT THE HULUNBUIR UNIVERSITY)
Authors:   Hulunbuir University (Hailar, Inner Mongolia, People’s Republic of China), Guang Feng
Published: April 2021

Friendship and cooperation between China and Russia have a long history. In the 21 st century, the impetus to these relations was given by the Chinese Belt and Road Initiative. This program which intensifies cooperation between the two countries in many areas and, in turn, significantly contributes to a great demand for specialists with higher education who are proficient in Russian. Responding to these needs, more and more educational institutions in China are offering specialties related to the study of the Russian language. At the Hulunbuir University, the Russian Language specialty was founded in 1990, while the course in Translation Studies was included in the curriculum in 2015. With sufficient amount of available material for teaching this course, in effect, there are several difficulties which are encountered: – lack of experience in teaching a new course; – need for advanced training and retraining of teachers in Translation Studies; – difficulty in selecting appropriate textbooks; – need to constantly update teaching methods in accordance with modern technology development; – issues experienced by students in practical translation, etc. This article discusses all these difficulties and ways to overcome them.
Ankle Stability and Movement Coordination Impairments: Lateral Ankle Ligament Sprains Revision 2021
Authors: Martin Robroy L. , Davenport Todd E. , Fraser John J. , Sawdon-Bea Jenna , Carcia Christopher R. , Carroll Lindsay A. , Kivlan Benjamin R. , Carreira Dominic
Published: April 2021

This revised clinical practice guideline (CPG) addresses the distinct but related lower extremity impairments of those with a first-time lateral ankle sprain (LAS) and those with chronic ankle instability (CAI). Depending on many factors, impairments may continue following injury. While most individuals experience resolution of symptoms, complaints of instability may continue and are defined as CAI. The aims of the revision were to provide a concise summary of the contemporary evidence since publication of the original guideline and to develop new recommendations or revise previously published recommendations to support evidence-based practice. J Orthop Sports Phys Ther 2021;51(4):CPG1–CPG80. doi:10.2519/jospt.2021.0302
THE URGENCY OF MORTGAGE AGREEMENT AS AN EFFORT TO REALIZE THE TRUST BY BANK AS CREDITOR
Authors: Atikah Ika
Published: April 2021

This study focuses on the legal certainty of the implementation of loans for mortgage rights which are the object of collateral in the form of money-valued objects when bad loan occurs, which are regulated in the main agreement as an effort to manifest the trust of creditors of banking institutions whose existence is highly sought after by the Indonesian people. The method used in this study focuses on the normative with the conceptual approach and statute approach. The results of this study indicate that Credit agreements must be considered by the bank as creditor and by the customer as the debtor, considering that credit agreements have a vital function in granting, managing, and managing the credit itself. The existence of a guarantee in a bank credit agreement is significant, namely as a means of legal protection for bank security in overcoming risks. There is a certainty that the debtor customer will pay off his loan. This is based on the explanation of Banking Laws, PBI, and POJK, which requires banks' caution as creditors for loans to debtors based on the belief in the debtor's ability to pay off his obligations as agreed in the agreement. The land is material security which is most in demand by banking institutions as security of mortgage rights. The use of land as a trusted and consumptive credit is based on the consideration of the safest land and has a relatively high sale value. The urgency of objects Securing mortgage rights as stipulated in the credit agreement cannot be separated from the guarantee itself. Credit guarantees are always stated in an additional agreement, namely the Collateral agreement. The need for funds by people or institutions provides credit by providing excellent services and providing legal protection for the parties in the transaction so that no one is harmed in the transaction. The state provides legal protection by stipulating legal regulation relating to credit so that banks as creditors have legal certainty in the process of executing credit collateral objects for optimal repayment. Mortgage Law states that creditors have full rights in executing debtor's collateral goods when bad loans do not have to go through litigation.
Self-Compassion and Forgiveness among Senior High School Students: A Correlational and Comparative Study
Authors: Wibowo Mungin Eddy , Naini Rohmatus
Published: April 2021

The problem of low self-compassion and forgiveness in schools causes students to often feel stress and depression, blame themselves, and label themselves to do self-harm. The inability to accept oneself leads to the rejection of unpleasant experiences, failure, and imperfection. This study aims to examine the relationship between self-compassion and forgiveness among students at three Senior High Schools located in the City of Semarang, Indonesia. There were 178 students who were involved in this study with the age range from 14 to 17 years old. The authors used the self-compassion scale, which has 26 items by measuring six sub-aspects including self-kindness, self-judgment, common humanity, isolation, mindfulness, and over-identification. The author used 10 items of the trait forgiveness scale (TFS). The results showed that there is a positive relationship between self-compassion and forgiveness and showed no differences between self-compassion and forgiveness when viewed by gender.
Os benefícios da aromaterapia e dos cosméticos orgânicos na recuperação de pacientes com câncer de mama e o papel do enfermeiro
Authors: Da Silva Deborah , Paganini Maria Cristina
Published: April 2021

Objetivo: Descrever os benefícios da aromaterapia e os cosméticos orgânicos para pacientes com câncer de mama e a atuação do enfermeiro nas orientações e indicações de uso para a recuperação e tratamento. Métodos: Tratou-se de um artigo de revisão de literatura, realizou-se um levantamento nas diferentes bases de dados como: SCIELO, BVS, Google Acadêmico, LILACS, MEDLINE, revistas e sites de órgãos regulatórios, publicados entre 2005 à 2020. Resultados: Foram incluídos 27 artigos no estudo e identificadas 4 categorias distintas, sendo elas: Reações Adversas da Quimioterapia e Radioterapia no Paciente Oncológico; O Câncer de Mama e os Cosméticos; Cosméticos Orgânicos ou Biocosméticos e O Papel do enfermeiro na Recuperação de Pacientes com Câncer de Mama em Uso de Aromaterapia. Considerações finais: A aromaterapia é uma prática que faz parte das Práticas Integrativas Complementares em Saúde (PICS), ainda pouco utilizada no Brasil pelos enfermeiros, porém respaldada pelo COFEN, vem se expandindo e inserindo o enfermeiro nesse cenário, sendo fundamental no sucesso da recuperação da paciente com câncer de mama.
Hemodiyaliz Tedavisi Uygulanan Kronik Böbrek Yetmezliği Hastalarında Hemşirelik Tanıları
Authors: ESKİMEZ Zehra , KÖSE TOSUNÖZ İpek , KESKİN Alev , KURT Ece , PAYDAS Saime , KAYA Bülent
Published: April 2021

Bu çalışma, hemodiyaliz tedavisi gören kronik böbrek yetmezliği hastalarının Roper, Logan, Tierney'in Yaşam Aktivitelerine Dayalı Hemşirelik Modeli’nden yararlanarak hemşirelik tanılarının belirlenmesi amacıyla planlanmıştır. Tanımlayıcı ve kesitsel tipte yapılan çalışmanın evrenini bir üniversite hastanesinin hemodiyaliz ünitesinde düzenli hemodiyaliz tedavisi gören 66 hasta oluşturmuş olup örneklemini araştırmaya katılma kriterlerine uyan 42 hasta oluşturmuştur. Araştırma öncesi, etik kurul onayı ve kurum izni alınmıştır. Araştırmanın verileri literatürden yararlanılarak araştırmacılar tarafından hazırlanan “Hasta Bilgi formu” ve Hemşirelik Modeli’ne uygun günlük yaşam aktivitelerine göre oluşturulan “Bakım Gereksinimlerini Belirleme Formu” kullanılarak toplanmıştır. Toplanılan veriler analiz edilerek uygun NANDA-I tanıları konulmuştur. Verilerin analizinde sayı ve yüzde değerleri kullanılmıştır. Hastaların yaş ortalamaları 57.31+16.59 olup %54.8’i kadındır. Toplamda 12 günlük yaşam aktivitesine ait 45 NANDA-I hemşirelik tanısı saptanmıştır. Bu tanıların altı tanesi tüm hastalarda (%100) görülen hemşirelik tanısı olup bu tanılar; “Enfeksiyon Riski”, “Kanama Riski”, “Elektrolit Dengesizliği Riski”, “Etkisiz Renal Perfüzyon Riski”, “Vücut Sıcaklığında Bozulma Riski” ve “Deri Bütünlüğünde Bozulma”dır. Belirlenen hemşirelik tanılarından %83.33’ü gerçek hemşirelik tanısıdır. Hemodiyaliz tedavisi uygulanan kronik böbrek yetmezliği hastalarının yaşadıkları ortak sorunlara yönelik hemşirelik tanılarının belirlenmesi ve bu sorunların belirlenmesinde Hemşirelik Modelinin kullanılması, uygulanacak hemşirelik bakımında sistematik yaklaşım ile birlikte bakımın kalitesini artıracaktır.
Proxapertites from Walat Formation, Sukabumi, West Java, Indonesia
Authors: Rachman Rizki Satria , Winantris  , Muljana Budi
Published: April 2021

Proxapertites have become one of the most significant indicators of ancient rock in Indonesia. Walat Formation is one of the oldest rocks exposed in Sukabumi, West Java, Indonesia. These Proxapertites have not been described in detail about their characteristics in previous studies, especially on Walat Formation. Therefore, knowing the characteristics of Proxapertites becomes interesting, especially in Walat Formation, which can be a reference for the characteristics of the late Eocene Proxapertites (37.8 - 33.9 million) in Indonesia. Acetolysis method was carried out for the preparation of pollen and spores; description and determination were carried out to see the characteristics of Proxapertites that present in Walat Formation. Result, there are three types of Proxapertites. Proxapertites operculatus have sizes 23 – 86 µ with average 40.5 (P) and 51.1 (E) µ, index PE 0,43 - 1, Peroblate – Subspheroidal – Oblate Spheroidal, Fine-Reticulate ornamentation, and Asymmetric Monosulcate aperture. Proxapertites cursus have sizes 23 – 86 µ with average 39.8 (P) and 49.8 (E) µ, index PE 0.51 - 1, Oblate – Subspheroidal – Oblate Spheroidal, Reticulate ornamentation, and Asymmetric Monosulcate aperture. Whereas Proxapertites psilatus have sizes 29 – 75 µ with average 42.3 (P) and 52.5 (E) µ, index PE 0.58 - 1, Oblate – Subspheroidal – Oblate Spheroidal, Psilate ornamentation, and Asymmetric Monosulcate aperture. These three Proxapertites can be distinguished by their type of ornamentation. Meanwhile, other aspects have similar characteristics and are affected by the appearance of individual pollen on the slide during preparation.
ON SUFFICIENT CONDITIONS OF EXPONENTIAL STABILITY FOR SYSTEMS OF LINEAR AUTONOMOUS DIFFERENTIAL EQUATIONS WITH AFTEREFFECT
Authors: SABATULINA T. SABATULINA
Published: April 2021

We consider systems of linear autonomous functional diﬀerential equa-tion with aftereﬀect and propose an approach to obtain eﬀective suﬃcient conditions of exponential stability for these systems. In the approach we use the positiveness of the fundamental matrix of an auxiliary system (a comparison system) with concentrated and distributed delays.
Design, Synthesis and Biological Evaluation of Novel SARS-CoV-2 3CLpro Covalent Inhibitors
Authors: Stille Julia , Tjutrins Jevgenijs , Wang Guanyu , Venegas Felipe A. , Hennecker Christopher , Rueda Andres Mauricio , Sharon Itai , Miron Caitlin E. , Pinus Sharon , Labarre Anne , Plescia Jessica , Patrascu Mihai Burai , Zhang Xiaocong , Wahba Alexander S. , Vlaho Danielle , Huot Mitchell , Schmeing T. Martin , Mittermaier Anthony K , Moitessier Nicolas
Published: April 2021

Severe diseases such as the ongoing COVID-19 pandemic, as well as the previous SARS and MERS outbreaks, are the result of coronavirus infections and have demonstrated the urgent need for antiviral drugs to combat these deadly viruses. Due to its essential role in viral replication and function, 3CLpro has been identified as a promising target for the development of antiviral drugs. Previously reported SARS-CoV 3CLpro non-covalent inhibitors were used as a starting point for the development of covalent inhibitors of SARS-CoV-2 3CLpro. We report herein our efforts in design and synthesis which led to submicromolar covalent inhibitors when the enzymatic activity of the viral protease was used as a screening platform.
FID-Net: A Versatile Deep Neural Network Architecture for NMR Spectral Reconstruction and Virtual Decoupling
Authors: Karunanithy Gogulan , Hansen Flemming
Published: April 2021

In recent years, the transformative potential of deep neural networks (DNNs) for analysing and interpreting NMR data has clearly been recognised. However, most applications of DNNs in NMR to date either struggle to outperform existing methodologies or are limited in scope to a narrow range of data that closely resemble the data that the network was trained on. These limitations have prevented a widescale uptake of DNNs in NMR. Addressing this, we introduce FID-Net, a deep neural network architecture inspired by WaveNet, for performing analyses on time domain NMR data. We first demonstrate the effectiveness of this architecture in reconstructing non-uniformly sampled (NUS) biomolecular NMR spectra. It is shown that a single network is able to reconstruct a diverse range of 2D NUS spectra that have been obtained with arbitrary sampling schedules, with a range of sweep widths, and a variety of other acquisition parameters. The performance of the trained FID-Net in this case exceeds or matches existing methods currently used for the reconstruction of NUS NMR spectra. Secondly, we present a network based on the FID-Net architecture that can efficiently virtually decouple 13Cα-13Cβ couplings in HNCA protein NMR spectra in a single shot analysis, while at the same time leaving glycine residues unmodulated. The ability for these DNNs to work effectively in a wide range of scenarios, without retraining, paves the way for their widespread usage in analysing NMR data.
A Study with Peptide Dendrimers Reveals an Extreme pH Dependence of Antibiotic Activity Above pH 7.4
Authors: Cai Xingguang , Javor Sacha , Gan Bee-Ha , Köhler Thilo , Reymond Jean-Louis
Published: April 2021

The presence of ionizable groups in antimicrobial peptides (AMPs) often induces a pH-dependent activity. Herein we report that removing eight low pKa amino termini in antimicrobial peptide dendrimer (AMPD) G3KL provides dendrimer XC1 with a broader pH-activity range. Furthermore, raising the pH to 8.0 reveals strong activities against Klebsiella pneumoniae and methicillin resistant Staphylococcus aureus (MRSA) against which these AMPDs are inactive at pH 7.4. We observe a similar effect with polymyxin B on MRSA. Binding experiments with a fluorescent AMPD and the effect of high salt concentration suggest that the activity increase reflects stronger electrostatic binding to the bacteria at high pH. pH-profiling of other polycationic antimicrobials (polymers, peptidomimetics, foldamers, dendrimers) might similarly enhance their activity range, with possible use for topical treatments.
ABA Type Amphiphiles with Poly(2-Benzhydryl-2-Oxazine) Moieties: Synthesis, Characterization and Inverse Thermogelation
Authors: Hahn Lukas , Keßler Larissa , Polzin Lando , Fritze Lars , Helten Holger , Luxenhofer Robert
Published: April 2021

Thermoresponsive polymers are frequently discussed for various applications. Here, we introduce a novel amphiphilic triblock copolymer, which undergoes inverse thermogelation, i.e. is forms a physical gel upon cooling. The polymers comprises poly(2-benzhydryl-2-oxazine) as the hydrophobic building block, a polymer which has not been reported to date. The physical gels are surprisingly strong with a storage modulus of 22 kPa at 25 wt.% in water. In addition, relatively high yield and flow points were determined by rheology.
High-Entropy 2D Carbide MXenes
Authors: Nemani Srinivasa Kartik , ZHANG BOWEN , Wyatt Brian C. , Hood Zachary D. , Manna Sukriti , Khaledialidusti Rasoul , Hong Weichen , Sternberg Michael G. , Sankaranarayanan Subramanian , Anasori Babak
Published: April 2021

Two-dimensional (2D) transition metal carbides and nitrides, known as MXenes, are a fast-growing family of 2D materials. MXenes 2D flakes have n + 1 (n = 1 – 4) atomic layers of transition metals interleaved by carbon/nitrogen layers, but to-date remain limited in composition to one or two transition metals. In this study, through the use of four transition metals, we report the synthesis of multi-principal element high-entropy M4C3Tx MXenes. Specifically, we introduce two high-entropy MXenes, TiVNbMoC3Tx and TiVCrMoC3Tx, as well as their precursor TiVNbMoAlC3 and TiVCrMoAlC3 high-entropy MAX phases. We used a combination of real and reciprocal space characterization (x-ray diffraction, x-ray photoelectron spectroscopy, energy dispersive x-ray spectroscopy, and scanning transmission electron microscopy) to establish the structure, phase purity, and equimolar distribution of the four transition metals in high-entropy MAX and MXene phases. We use first-principles calculations to compute the formation energies and explore synthesizability of these high-entropy MAX phases. We also show that when three transition metals are used instead of four, under similar synthesis conditions to those of the four-element MAX phase, two different MAX phases can be formed (i.e. no pure single-phase forms). This finding indicates the importance of configurational entropy in stabilizing the desired single-phase high-entropy MAX over multiphases of MAX, which is essential for the synthesis of phase-pure high-entropy MXenes. The synthesis of high-entropy MXenes significantly expand the compositional variety of the MXene family to further tune their properties, including electronic, magnetic, electrochemical, catalytic, high temperature stability, and mechanical properties.
Nickel-Catalyzed Ipso-Borylation of Silyloxyarenes via C–O Bond Activation
Authors: Pein Wesley , Wiensch Eric , Montgomery John
Published: April 2021

A mild method to convert silyloxyarenes to pinacol boronic esters using nickel catalysis is described. In contrast to other borylation protocols of relatively inert C–O bonds, the method is competent in activating the carbon-oxygen bond of silyloxyarenes in isolated aromatic systems lacking a directing group. The catalytic functionalization of benzyl silyl ethers was also achieved under these conditions. Orthogonal reactivity of silyloxyarenes vs other electrophiles was demonstrated in the case of several cross-coupling reactions wherein the unaffected silyloxarene could be functionalized subsequently.
Column Generation Model in Capacitated Multi-Periods Cutting Stock Problem with Pattern Set-Up Cost
Authors: Bangun Putra Bahtera Jaya , Octarina Sisca , Hanum Laila , Sawitri Ranti , Cahyono Endro Sastro
Published: April 2021

Cutting Stock Problem (CSP) determines the cutting of stocks with standard length and width to meet the item’s demand. The optimal cutting pattern will minimize the usage of stocks and trim loss. This research implemented the pattern generation algorithm to form the Gilmore-Gomory and Column Generation model in two-dimensional CSP. The CSP in this research had three periods of cutting with different capacities in each period. The Column Generation model added the pattern set-up cost as the constraint. The Gilmore-Gomory model ensured that the first stage’s strips were used in the second stage and met the item’s demand. Based on the Column Generation model’s solution, the 1st period used the 2nd, 4th, and 5th patterns, the 2nd period used 4th and 5th patterns, and the 3rd period did not use any patterns. The first and second periods fulfilled all of the demands.
Visual Perturbation to Enhance Return to Sport Rehabilitation after Anterior Cruciate Ligament Injury: A Clinical Commentary
Authors: Wohl Timothy R , Criss Cody R , Grooms Dustin R
Published: April 2021

Anterior cruciate ligament (ACL) tears are common traumatic knee injuries causing joint instability, quadriceps muscle weakness and impaired motor coordination. The neuromuscular consequences of injury are not limited to the joint and surrounding musculature, but may modulate central nervous system reorganization. Neuroimaging data suggest patients with ACL injuries may require greater levels of visual-motor and neurocognitive processing activity to sustain lower limb control relative to healthy matched counterparts. Therapy currently fails to adequately address these nuanced consequences of ACL injury, which likely contributes to impaired neuromuscular control when visually or cognitively challenged and high rates of re-injury. This gap in rehabilitation may be filled by visual perturbation training, which may reweight sensory neural processing toward proprioception and reduce the dependency on vision to perform lower extremity motor tasks and/or increase visuomotor processing efficiency. This clinical commentary details a novel approach to supplement the current standard of care for ACL injury by incorporating stroboscopic glasses with key motor learning principles customized to target visual and cognitive dependence for motor control after ACL injury.

Level of Evidence

5
The Dorsiflexion Range of Motion Screen: A Validation Study
Authors: Plisky Phillip J , Bullock Garrett S , Garner Mary Beth , Ricard Risa , Hayden Josh , Huebner Bethany , Schwartzkopf-Phifer Kate , Kiesel Kyle
Published: April 2021

Background

Limited ankle dorsiflexion (DF) is associated with ankle sprains and other lower extremity injuries. Current ankle measurements can be laborious to perform in an athletic environment.

Purpose

The purpose of this study was to determine the reliability and discriminant validity of a novel closed-chain ankle DF ROM test, the standing ankle dorsiflexion screen (SADS).

Study Design

Reliability and validity study

Methods

Thirty-seven healthy subjects participated in the study. Two raters measured closed-chain ankle DF range of motion (ROM) using a modified lunge position with an electronic inclinometer. Four raters measured ankle DF using the SADS. Reliability was calculated using intraclass correlation coefficients (ICC) and kappa coefficients for the raters using an electronic inclinometer and the SADS scale, respectively. An independent t-test compared the SADS categories of “behind” and “beyond” to the modified lunge test ROM (p<0.05).

Results

Excellent ICC values (0.95 [95% CI (0.92,0.97)]) and high kappa values were observed (0.61-0.81), with high percent agreement (86-94%). There was a significant difference in ankle DF ROM between the nominally scored “behind” and “beyond” categories, regardless of rater or trial analyzed (behind: 41.3° ± 4.7°; beyond: 51.8°± SD 6.1°, p <0.001).

Conclusions

The SADS was observed to have excellent interrater reliability and high discriminant validity. Furthermore, there was a distinct closed chain ankle DF ROM difference between the “behind” and “beyond” SADS nominal scores.

Clinical Relevance

The SADS can be used as a quick and efficient closed chain ankle DF ROM screen.

Level of Evidence

2b
Quanto dura uma catástrofe? nação, indivíduo e trauma na Gripe Espanhola
Authors: Vaz Paulo , Sanchotene Nicole , Santos Amanda
Published: April 2021

Diante dos diagnósticos na mídia de que a pandemia de Covid-19 será traumática, propõe-se uma reflexão sobre os modos de articular sofrimento e futuro. A análise do jornal Correio da Manhã durante a Gripe Espanhola sugere que já houve outra maneira de atribuir sentido ao sofrimento que não o trauma. Dada a suposição hoje prevalente de que a epidemia de 1918 foi traumática e de que houve um silenciamento das vítimas, voltar à cobertura jornalística sobre a Gripe Espanhola pode servir para entender qual foi a narrativa daquele evento e realçar a singularidade nossa de habitar o tempo.
História do jornalismo em Portugal: proposta de periodização
Authors: Sousa Jorge Pedro , Lima Helena
Published: April 2021

A periodização sistematiza e ordena diacronicamente os fenómenos históricos, agrupando-os de acordo com denominadores comuns e assinalando continuidades e ruturas evidentes e verificáveis na evolução histórica. Assenta, metodologicamente, num exercício intelectual interpretativo que parte da evidência histórica, embora nunca adira inteiramente à realidade histórica material. O presente trabalho visou, assim, propor uma periodização para a história do jornalismo português, que nunca terá sido esboçada. Definiram-se os seguintes períodos 1) Periodismo artesanal noticioso; 2) Segmentação da imprensa e domínio da imprensa artesanal informativa; 3) Domínio da imprensa artesanal política; 4) Imprensa pré-industrial segmentada; 5) Imprensa industrial segmentada e desenvolvimento dos diários noticiosos de massas; 6) Segmentação mediática do jornalismo, com três fases: a) Máquinas censuradas; b) Disrupção revolucionária; c) Liberalização; e 7) Convergência e fusão.Palavras-chave: Jornalismo. História. Periodização. Portugal.
Expediente
Authors: De História da Mídia Associação Brasileira De Pesquisadores
Published: April 2021

Expediente
De volta para o futuro: tecnologias e agenciamentos entre livros e leituras
Authors: Vieira Taynée Mendes , Gonçalves Márcio Souza
Published: April 2021

O presente artigo revisita o pensamento de autores clássicos da história do livro e da leitura para levantar pontos de tensão relevantes para a discussão da leitura no universo digital. Trata-se aqui, sobretudo, de problematizar uma visão linear dessas histórias, da leitura em voz em alta, durante a Idade Média, à informatização do escrito, no fim do século XX, abrindo espaço para uma concepção complexa e nuançada da relação entre leitura, tecnologia e cultura na história. Apresentamos inicialmente a visão dos principais marcos da história da livro – a invenção da escrita, o surgimento do códice, a expansão da impressão e a recente digitalização – a fim de discutir alguns pressupostos importantes para entender a leitura hoje. Por fim, concluímos que se deve evitar uma visão histórica linear e investir na ideia de que há diversos agentes além do tecnológico para se estudar e compreender diferentes práticas de leitura.Palavras-chave: História do livro. Práticas de leitura. Manuscrito. Impresso. Digital.
Related-Party Transactions and Audit Fees
Authors: Perwita Fortuna Oktavia , Harymawan Iman
Published: April 2021

This research aims to analyze the association between the related-party transactions and audit fees. This study used 781 observations listed on the Indonesia Stock Exchange from 2010 to 2017. The analysis technique used in this research was the Ordinary Least Square Regression analysis model processed with STATA 14.0 software.  This study found that related-party transactions are positively and significantly related to audit fees. The result indicated that the related-party transactions increase audit fees paid by companies. It also investigated the moderating effect of industry specialty auditors. This indicated that auditor specialization strengthened the relationship between the related-party transactions and audit fees. The market share proxy was used to measure industry specialization. However, this proxy still has disadvantages as it can generate different market shares. This study found that related-party transactions increased audit fees. The results of this study can be used as consideration in making decisions for related parties.