bluuebunny/crossref_metadata_2025 huggingface dataset:
Make It New
Authors: Katz Barry M.
Published: May 2016

The role of design in the formation of the Silicon Valley ecosystem of innovation.

California's Silicon Valley is home to the greatest concentration of designers in the world: corporate design offices at flagship technology companies and volunteers at nonprofit NGOs; global design consultancies and boutique studios; research laboratories and academic design programs. Together they form the interconnected network that is Silicon Valley. Apple products are famously “Designed in California,” but, as Barry Katz shows in this first-ever, extensively illustrated history, the role of design in Silicon Valley began decades before Steve Jobs and Steve Wozniak dreamed up Apple in a garage.

Offering a thoroughly original view of the subject, Katz tells how design helped transform Silicon Valley into the most powerful engine of innovation in the world. From Hewlett-Packard and Ampex in the 1950s to Google and Facebook today, design has provided the bridge between research and development, art and engineering, technical performance and human behavior. Katz traces the origins of all of the leading consultancies—including IDEO, frog, and Lunar—and shows the process by which some of the world's most influential companies came to place design at the center of their business strategies. At the same time, universities, foundations, and even governments have learned to apply “design thinking” to their missions. Drawing on unprecedented access to a vast array of primary sources and interviews with nearly every influential design leader—including Douglas Engelbart, Steve Jobs, and Don Norman—Katz reveals design to be the missing link in Silicon Valley's ecosystem of innovation.
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics
Authors: Abedini Andisheh , Plesner Annette , Cao Ping , Ridgway Zachary , Zhang Jinghua , Tu Ling-Hsien , Middleton Chris T , Chao Brian , Sartori Daniel J , Meng Fanling , Wang Hui , Wong Amy G , Zanni Martin T , Verchere C Bruce , Raleigh Daniel P , Schmidt Ann Marie
Published: May 2016

Islet amyloidosis by IAPP contributes to pancreatic β-cell death in diabetes, but the nature of toxic IAPP species remains elusive. Using concurrent time-resolved biophysical and biological measurements, we define the toxic species produced during IAPP amyloid formation and link their properties to induction of rat INS-1 β-cell and murine islet toxicity. These globally flexible, low order oligomers upregulate pro-inflammatory markers and induce reactive oxygen species. They do not bind 1-anilnonaphthalene-8-sulphonic acid and lack extensive β-sheet structure. Aromatic interactions modulate, but are not required for toxicity. Not all IAPP oligomers are toxic; toxicity depends on their partially structured conformational states. Some anti-amyloid agents paradoxically prolong cytotoxicity by prolonging the lifetime of the toxic species. The data highlight the distinguishing properties of toxic IAPP oligomers and the common features that they share with toxic species reported for other amyloidogenic polypeptides, providing information for rational drug design to treat IAPP induced β-cell death.
Functional synergy between the Munc13 C-terminal C1 and C2 domains
Authors: Liu Xiaoxia , Seven Alpay Burak , Camacho Marcial , Esser Victoria , Xu Junjie , Trimbuch Thorsten , Quade Bradley , Su Lijing , Ma Cong , Rosenmund Christian , Rizo Josep
Published: May 2016

Neurotransmitter release requires SNARE complexes to bring membranes together, NSF-SNAPs to recycle the SNAREs, Munc18-1 and Munc13s to orchestrate SNARE complex assembly, and Synaptotagmin-1 to trigger fast Ca2+-dependent membrane fusion. However, it is unclear whether Munc13s function upstream and/or downstream of SNARE complex assembly, and how the actions of their multiple domains are integrated. Reconstitution, liposome-clustering and electrophysiological experiments now reveal a functional synergy between the C1, C2B and C2C domains of Munc13-1, indicating that these domains help bridging the vesicle and plasma membranes to facilitate stimulation of SNARE complex assembly by the Munc13-1 MUN domain. Our reconstitution data also suggest that Munc18-1, Munc13-1, NSF, αSNAP and the SNAREs are critical to form a ‘primed’ state that does not fuse but is ready for fast fusion upon Ca2+ influx. Overall, our results support a model whereby the multiple domains of Munc13s cooperate to coordinate synaptic vesicle docking, priming and fusion.
Olfactory channels associated with the Drosophila maxillary palp mediate short- and long-range attraction
Authors: Dweck Hany KM , Ebrahim Shimaa AM , Khallaf Mohammed A , Koenig Christopher , Farhan Abu , Stieber Regina , Weißflog Jerrit , Svatoš Aleš , Grosse-Wilde Ewald , Knaden Markus , Hansson Bill S
Published: May 2016

The vinegar fly Drosophila melanogaster is equipped with two peripheral olfactory organs, antenna and maxillary palp. The antenna is involved in finding food, oviposition sites and mates. However, the functional significance of the maxillary palp remained unknown. Here, we screened the olfactory sensory neurons of the maxillary palp (MP-OSNs) using a large number of natural odor extracts to identify novel ligands for each MP-OSN type. We found that each type is the sole or the primary detector for a specific compound, and detects these compounds with high sensitivity. We next dissected the contribution of MP-OSNs to behaviors evoked by their key ligands and found that MP-OSNs mediate short- and long-range attraction. Furthermore, the organization, detection and olfactory receptor (Or) genes of MP-OSNs are conserved in the agricultural pest D. suzukii. The novel short and long-range attractants could potentially be used in integrated pest management (IPM) programs of this pest species.
Comprehensive Evaluation for Obesity: Beyond Body Mass Index
Authors: Cetin Derrick , Lessig Bailey A. , Nasr Elie
Published: May 2016

Many factors contribute to the diagnosis of obesity in a patient. Anthropometric measurements, such as the waist circumference and percentage of body fat, are used in the newly released obesity algorithm to risk stratify patients. Staging methods, which use the identification of comorbidities and disease burden to assess the severity of obesity, can result in treating a patient sooner than if the traditional body mass index is used. Obesity is a growing concern in the medical field, and providing additional avenues through which to diagnose obesity and address obesity-related health risks can improve prevention efforts and lead to expedited weight management. Obesity is a growing concern in the medical field, and providing additional avenues through which to diagnose obesity and address obesity-related health risks can improve prevention efforts and lead to expedited weight management.
Ensino com Pesquisa: Contribuições para a Cientificidade na Formação em Secretariado Executivo
Authors: Pinheiro Barros Conceição de Maria , Da Silva Joelma Soares , Barros Ana Paula da Cruz Holanda
Published: May 2016

O ensino com pesquisa pode ser considerado como um método capaz de contribuir para a docência universitária, inserindo-se nesse contexto a formação em Secretariado Executivo. Este trabalho tem por objetivo geral investigar as contribuições dessa abordagem para a cientificidade secretarial. Para tanto, foi desenvolvida uma pesquisa qualitativa utilizando-se como técnicas de pesquisa observação participante e narrativa escrita. A partir da observação participante, registrada em diário de campo, apresenta-se o relato de experiência docente por meio da descrição do desenvolvimento e dos resultados alcançados com a utilização do ensino com pesquisa científica desenvolvido nas disciplinas Dinâmica Gerencial, Comportamento Organizacional e Estágio Supervisionado, no Curso de Secretariado Executivo da Universidade Federal do Ceará, no período de 2012 a 2014, com a participação 73 alunos. As narrativas escritas foram realizadas por 19 estudantes que desenvolveram o Estágio Supervisionado, em 2014. A interpretação das informações foi realizada numa perspectiva hermenêutica fundamentada na compreensão interpretativa fenomenológica. Inferiu-se que as contribuições do ensino com pesquisa para a cientificidade secretarial ocorrem principalmente, pelo fato de formar um novo perfil acadêmico e profissional por meio de uma cultura científica no Curso, inserindo o educando no processo investigativo durante a realização das disciplinas estudadas ao longo de sua trajetória universitária. Tal cultura possibilita a busca por respostas às inquietações que surgem na profissão, colaborando para a identidade do Secretariado como área de conhecimento em construção.
Imagem(Ns) do Sujeito-Aluno de Secretariado Executivo Trilíngue acerca de Si E do Profissional da Área
Authors: Mareco Raquel Tiemi Masuda , Birello Verônica Braga
Published: May 2016

Este artigo tem como objetivo principal investigar quais imagens são sustentadas pela memória discursiva do sujeito-aluno de Secretariado Executivo Trilíngue e acerca de si e do profissional da área. Buscamos, dessa forma, observar as projeções imaginárias do estudante no processo de significação discursiva acerca de si e do profissional atuante em pesquisa aplicada com os acadêmicos do segundo ano do curso em uma universidade estadual do estado do Paraná. Para tanto, procuramos levantar e apresentar os pré-construídos que circulam em nossa sociedade sobre o profissional de secretariado, por meio de uma contextualização histórica. Dessa forma, foi possível apontar como a memória discursiva funciona na sustentação da(s) imagem(ns) do sujeito-aluno ao enunciar sobre si e sobre o profissional. Para tanto partiremos das teorias da Análise do Discurso francesa com Pêcheux (1995; 1999; 2008) bem como seus desdobramentos do Brasil com Orlandi (2005). Ainda tomamos por base autores como Achard (1999) e Davallon (1999) para discutir alguns aspectos que dizem respeito à memória discursiva. Para tratar questões relativas às condições de produção especificas do secretariado temos por base trabalhos de Portela (2013), Birello e Mareco (2012 e 2013), além de outros autores consideráveis para nossa pesquisa.
Melt‐rock interactions and fabric development of peridotites from North Pond in the Kane area, Mid‐Atlantic Ridge: Implications of microstructural and petrological analyses of peridotite samples from IODP Hole U1382A
Authors: Harigane Yumiko , Abe Natsue , Michibayashi Katsuyoshi , Kimura Jun‐Ichi , Chang Qing
Published: May 2016

North Pond is an isolated sedimentary pond on the western flank of the Kane area along the Mid‐Atlantic Ridge. Drill‐hole U1382A of IODP Expedition 336 recovered peridotite and gabbro samples from a sedimentary breccia layer in the pond, from which we collected six fresh peridotite samples. The peridotite samples came from the southern slope of the North Pond where an oceanic core complex is currently exposed. The samples were classified as spinel harzburgite, plagioclase‐bearing harzburgite, and a vein‐bearing peridotite that contains tiny gabbroic veins. No obvious macroscopic shear deformation related to the formation of a detachment fault was observed. The spinel harzburgite with a protogranular texture was classified as refractory peridotite. The degree of partial melting of the spinel harzburgite is estimated to be ∼17%, and melt depletion would have occurred at high temperatures in the uppermost mantle beneath the spreading axis. The progressive melt–rock interactions between the depleted spinel harzburgite and the percolating melts of Normal‐Mid Ocean Ridge Basalt (N‐MORB) produced the plagioclase‐bearing harzburgite and the vein‐bearing peridotite at relatively low temperatures. This implies that the subsequent refertilization occurred in an extinct spreading segment of the North Pond after spreading at the axis. Olivine fabrics in the spinel and plagioclase‐bearing harzburgites are of types AG, A, and D, suggesting the remnants of a mantle flow regime beneath the spreading axis. The initial olivine fabrics appear to have been preserved despite the later melt–rock interactions. The peridotite samples noted above preserve evidence of mantle flow and melt–rock interactions beneath a spreading ridge that formed at ∼8 Ma.
Resolution dependence of precipitation statistical fidelity in hindcast simulations
Authors: O'Brien Travis A. , Collins William D. , Kashinath Karthik , Rübel Oliver , Byna Suren , Gu Junmin , Krishnan Hari , Ullrich Paul A.
Published: May 2016

Numerous studies have shown that atmospheric models with high horizontal resolution better represent the physics and statistics of precipitation in climate models. While it is abundantly clear from these studies that high‐resolution increases the rate of extreme precipitation, it is not clear whether these added extreme events are “realistic”; whether they occur in simulations in response to the same forcings that drive similar events in reality. In order to understand whether increasing horizontal resolution results in improved model fidelity, a hindcast‐based, multiresolution experimental design has been conceived and implemented: the InitiaLIzed‐ensemble, Analyze, and Develop (ILIAD) framework. The ILIAD framework allows direct comparison between observed and simulated weather events across multiple resolutions and assessment of the degree to which increased resolution improves the fidelity of extremes. Analysis of 5 years of daily 5 day hindcasts with the Community Earth System Model at horizontal resolutions of 220, 110, and 28 km shows that: (1) these hindcasts reproduce the resolution‐dependent increase of extreme precipitation that has been identified in longer‐duration simulations, (2) the correspondence between simulated and observed extreme precipitation improves as resolution increases; and (3) this increase in extremes and precipitation fidelity comes entirely from resolved‐scale precipitation. Evidence is presented that this resolution‐dependent increase in precipitation intensity can be explained by the theory of Rauscher et al. (), which states that precipitation intensifies at high resolution due to an interaction between the emergent scaling (spectral) properties of the wind field and the constraint of fluid continuity.
ChemInform Abstract: Cs2TlBr5 ‐ a Pentabromothallate(III) with Tetrahedral TlBr4 ‐ and Octahedral TlBr3‐ 6 Anions.
Authors: ZIMMERMANN K. , THIELE G.
Published: May 2016

Addition of CsBr and HBr to an aqueous solution of TlBr3 yields Cs3Tl2Br9, which transforms within 1‐2 d into Cs2TlBr5 (yield in g).
ChemInform Abstract: The Influence of Substitution by Ions Having the Same Charge on the Luminescence‐Optical Properties of Ba0.9Eu0.1Mg2Al16O27.
Authors: NOETZOLD D. + , HERZOG G. , BRITZ A.
Published: May 2016

In the title phosphor, Sr has been substituted for Ba, Zn and/or Ca for Al, and Y or Gd for Al and the emission and excitation spectra of the substituted phosphors have been recorded.
ChemInform Abstract: Divalent Samarium: Synthesis and Crystal Structures of Sm4OCl6 (I) and KSm2Cl5 (II).
Authors: SCHLEID T. , MEYER G.
Published: May 2016

Single crystals of (I) and (II) have been prepared by metallothermic reductions of SmCl3 with Li (in the presence of Sm2O3 or SmOCl) and K, resp., in sealed tantalum tubes (I: 900 °C, 4 d, 750 °C, 6 d; II: 900 °C, 3 d, 750 °C, 4 d; fast cooling).
ChemInform Abstract: Magnetic Properties and EPR Spectra of Tetranuclear Copper(II) Complexes.
Authors: NEPVEU F.
Published: May 2016

Analysis of the low‐temp.
ChemInform Abstract: Applications of Cadmium NMR to Polycadmium Compounds. Part 5. Digonally Coordinated Halide Whithin an Octametal Cage. Crystal and Solution Structures of (XCd8(SCH2CH2OH)12X3), X: Cl, Br, I.
Authors: DANCE I. G. , GARBUTT R. G. , CRAIG D. C.
Published: May 2016

The iodo compound (IV) is known.
ChemInform Abstract: Promoter Effect of Iron on Olefin Hydroformylation Catalyzed by SiO2‐Supported Rhodium‐Iron Bimetallic Carbonyl Clusters: Rh‐Fe3+ Bimetallic Activation of Catalytic CO Insertion.
Authors: FUKUOKA A. , ICHIKAWA M. , HRILJAC J. A. , SHRIVER D. F.
Published: May 2016

Bimetallic Rh‐Fe3+ ensembles appear to be generated from the Rh‐Fe carbonyl clusters (I)‐(IV) supported on SiO2.
ChemInform Abstract: Electrocyclic Opening of 2,3‐Benzo‐ and 2,3;7,8‐Dibenzobicyclo(4.2.0)octa‐2,4,7‐triene; Benzoanellated Transition States.
Authors: GRIMME W. , LEX J. , SCHMIDT T.
Published: May 2016

The tricyclic compound (IV) is prepared in accordance with the scheme and isomerizes to give (VI).
ChemInform Abstract: A Photochemical Approach to the Bicyclo(5.3.1)undecane Ring System of Taxane Diterpenes.
Authors: BENCHICK‐LE‐HOCINE M. , DO KHAC DUC DO KHAC DUC , FETIZON M. , HANNA I. , ZEGHDOUDI R.
Published: May 2016

The bicyclic 1,3‐dione (I) undergoes addition reaction with allene (II) on irradiation in methanol to give the regioisomeric adducts (III) and (IV) which are formed via the enol of (I).
ChemInform Abstract: Question of 1,4‐Diradical Intermediates in the Di‐π‐methane Rearrangement of Benzobicyclo(3.2.1)octadienes: Azoalkanes as Mechanistic Probes.
Authors: ADAM W. , DOERR M. + , KRON J. , ROSENTHAL R. J.
Published: May 2016

Nitrogen extrusion of the azo compounds (I) gives as major products (II); the minor products (III) and (IV) on irradiation also give the benzocyclooctenes (II).
ChemInform Abstract: Carbene Rearrangements. Part 23. Reactions of 2,2,4,4‐Tetramethyl‐3‐methylenecyclobutylidene (V); Thermal Rearrangements of a 2‐Methylenebicyclo(2.1.0)pentane (VIII).
Authors: BRINKER U. H. , ERDLE W.
Published: May 2016

The mechanism and course of the pyrolysis (and photolysis as well, leading to the major compounds (VII) and (VIII) in yields of 40 and 35%, resp.) of the diazo compound (IV) (half‐life ca. 6700 s at 31.5 °C) is studied; the hydrocarbons (VII)‐(XIII) are obtained in a total yield of 72%.
ChemInform Abstract: Phase‐Transfer Permanganate Oxidation of Unfunctionalized Benzylic Positions.
Authors: GANNON S. M. , KRAUSE J. G.
Published: May 2016

The benzylic methylene groups in (I) and the benzylic alcohols (III) are oxidized with potassium permanganate under phase‐transfer conditions to give the ketones (II).
ChemInform Abstract: Selective Reduction of Conjugated Ethylenic Linkage in the Presence of Ion‐Exchange Resin Bound Borohydride.
Authors: NAG A. , SARKAR A. , SARKAR S. K. , PALIT S. K.
Published: May 2016

Sodium borohydride fixed on a polystyrene resin is employed as a reagent for the hydrogenation of the α,β‐unsaturated esters (I), yielding the saturated esters (II).
ChemInform Abstract: Kinetics and Mechanisms of Metal Reduction by Hemoglobin. Part 1. Reduction of Iron(III) Complexes.
Authors: EGUCHI L. A. , SALTMAN P.
Published: May 2016

The kinetics of the reduction of Fe(III) complexes of cyanide, nitrilotriacetate, citrate, EDTA, 2,3‐diphosphoglyceric acid and inorganic pyrophosphate by deoxyhemoglobin present in equilibrium with oxyhemoglobin can be described by two possible electron‐transfer mechanisms.
ChemInform Abstract: Gas Phase Reactions. Part 60. Methanimines RR′C=NR′′: Preparation and Photoelectron Spectra.
Authors: BOCK H. , DAMMEL R.
Published: May 2016

All 6 methanimines (IVa) and the hitherto unknown cyclopropanimine (IVb) are prepared by consecutive chlorination of gaseous alkylamines (I) and dehydrochlorination of the resulting N‐chloroamines (II) (isolable in high purity (yields up to 80%) but explosive in condensed phase) in one step (two‐bed flow reactor; yields up to 96%) and/or by pyrolyses of azides (III).
ChemInform Abstract: Pyridine N‐Oxides as Catalysts for Thione‐Thiol Rearrangement.
Authors: HARANO K. , SHINOHARA I. , MURASE M. , HISANO T.
Published: May 2016

The O,S‐dialkyl dithiocarbonates (I) rearrange in the presence of pyridine N‐oxide, yielding the S,S‐dialkyl dithiocarbonates (II).
ChemInform Abstract: Methylenecyclopropanes. Part 9. Methylenecyclopentanes by Metal‐Catalyzed (3 + 2) Cycloaddition of 1‐Methylene‐2‐(trimethylsilyl)cyclopropane with Electron‐Deficient Olefins.
Authors: BINGER P. , STERNBERG E. , WITTIG U.
Published: May 2016

The palladium‐catalyzed (3 + 2) cycloaddition between the title compound (I) and the electron‐deficient olefins (II), (VI) or (X) leads to the cyclopentanes (III), (IV), (VII), (VIII), (XI) and (XII) together with minor amounts of the regioisomers (V), (IX) and (XIII) ((IX) and (XIII) are single isomers with regard to the stereochemistry of the SiMe3 group).
ChemInform Abstract: Double Diastereoselection Operative During π‐Facially Selective Addition of Chiral 1‐Cyclopentenyllithium Reagents to (7R*)‐7‐Methyl‐7‐vinylbicyclo(3.2.0)hept‐2‐en‐6‐one.
Authors: PAQUETTE L. A. , LEARN K. S. , ROMINE J. L.
Published: May 2016

The vinylbicycloheptenone (I) is allowed to react with the cyclopentenyllithium compounds (II), (V), and (VIII), yielding the fused cyclooctenones (III) and (IV), (VI) and (VII), or (IX) and (X).
ChemInform Abstract: A Simple Synthesis of Macrocyclic Hydrocarbons by Metathesis of Cycloolefins.
Authors: WARWEL S. , KAETKER H. +
Published: May 2016

The macrocyclic dienes (II) are obtained by metathesis of the cycloalkenes (I) using rhenium heptoxide on alumina, activated by tetramethyltin.
ChemInform Abstract: Generation and (4 + 3) Cycloaddition of Cyclopentenylium‐2‐olate from 2‐Chlorocyclopentanone Under Alcoholysis Conditions.
Authors: FOEHLISCH B. + , JOACHIMI R.
Published: May 2016

The chlorocyclopentanone (Ia) undergoes methanolysis or trifluoroethanolysis to form the cyclopentanones (Ib) or (Ic).
ChemInform Abstract: Synthesis of Alkene‐Substituted Pentacyclo(5.4.0.02,6.03,10.05,9)undecanes. Part 2. Photoelectron Spectra and Electronic Structures of Substituted Pentacyclo(5.4.0.02,6.03,10.05,9)undecanes.
Authors: MARCHAND A. P. , HUANG C. , KAYA R. , BAKER A. D. , JEMMIS E. D. , DIXON D. A.
Published: May 2016

Photoelectron spectra are obtained for all (I).
ChemInform Abstract: Crystal and Molecular Structure of Two Calix(4)arenes Bridged at Opposite para Positions.
Authors: PAULUS E. , BOEHMER V. + , GOLDMANN H. , VOGT W.
Published: May 2016

The title compounds (IIIa) and (IIIb) are synthesized from the components (I) and (II).
ChemInform Abstract: An Efficient Route to Aminoanthraquinones and Derivatives via a Diels‐ Alder Reaction.
Authors: CHIGR M. , FILLION H. , ROUGNY A.
Published: May 2016

The 5‐hydroxynaphthoquinone derivatives (I) react with the aminodienes (II) to give the isomeric adducts (III) and (IV).
ChemInform Abstract: Preparation of an α,β‐Type of Ter‐ and Septithiophenes.
Authors: NAKAYAMA J. , MURABAYASHI S. , HOSHINO M.
Published: May 2016

2‐Chloroacetylthiophene (III), prepared from thiophene (I), is transformed into the terthiophene (VIIa) by substitution reaction with sodium sulfide (IV), followed by reductive cyclization and acid‐catalyzed dehydration.
ChemInform Abstract: A Novel Synthesis of Benzofuran and Related Compounds. Part 4. The Vilsmeier Reaction of 3,5‐Dimethoxyphenylthiomethyl Compounds.
Authors: HIROTA T. , TASHIMA Y. , SASAKI K. , NAMBA T. , HAYAKAWA S.
Published: May 2016

Alkylation of 3,5‐dimethoxythiophenol (I) with the halides (II) gives the phenylthiomethyl derivatives (III) which cyclize under Vilsmeier reaction conditions to produce a mixture of the benzothiophenes (V) ‐ (VII) or (VIII).
ChemInform Abstract: Methylthio‐ and Ethanediyldithio‐Substituted 1,6‐Dithiapyrenes and Their Charge‐Transfer Complexes: New Organic Molecular Metals.
Authors: NAKASUJI K. , SASAKI M. , KOTANI T. , MURATA I. , ENOKI T. , IMAEDA K. , INOKUCHI H. , KAWAMOTO A. , TANAKA J.
Published: May 2016

The bis(methylthio)dithiapyrene (I) gives 1:1 complexes with (IIa) (semiconductor), with (IIb) (metallic, sharp M‐I transition at 240 K, space group P1 with Z=1), with (IIc) (metallic, sharp M‐I transition at 125 K), with (III) and with (IV) (two crystalline phases; β‐form metallic, space group P1 with Z=1; α‐form semiconductor, space group P21/c with Z=4).
ChemInform Abstract: Reactions of Trialkyl(2‐ or 4‐quinolyl)borates.
Authors: ISHIKURA M. , ODA I. , KAMADA M. , TERASHIMA M.
Published: May 2016

2‐Bromoquinoline (I) is lithiated and then allowed to react with the trialkylboranes (II) to yield the 2‐alkylquinolines (III) after work‐up with a basic hydrogen peroxide solution.
ChemInform Abstract: Basic Hydrolysis of Thioacetals: New Convenient Preparation of Acyl Meldrum′s Acid.
Authors: HUANG X. , CHEN B.
Published: May 2016

Hydrolysis of the methylthioalkylidene Meldrum's acids (II), readily prepared from (I) by a procedure published in a previous paper, yields the acyl Meldrum's acids (III).
ChemInform Abstract: Azo Bridges from Azines. Part 7. Diels‐Alder Reactions with Inverse Electron Demand Between Isopyrazoles and Cycloalkenes or Cycloalkadienes. ‐ A Comparison of Acid Catalysis and Acceleration by Pressure.
Authors: BECK K. , HUENIG S. + , KLAERNER F.‐G. + , KRAFT P. , ARTSCHWAGER‐PERL U.
Published: May 2016

The acid‐catalyzed reaction of the isopyrazoles (Ia) and (Ib) with cycloalkenes such as (II), (IV), (VII), (X) or (XIII) yields the expected azo‐bridged cycloadducts as exemplified in the scheme for the products (III), (V), (VIII), and (XI) from (Ia).
ChemInform Abstract: 4‐(Phenylthio)pyrrole‐3‐carboxylic Acid Esters.
Authors: EIDEN F. , GRUSDT U.
Published: May 2016

The furancarboxylate (I) is transformed into a diastereomeric mixture of the dimethoxyfuran (III) which releases methanol upon distillation to yield the methoxyfuran (IV).
ChemInform Abstract: Synthesis and Reactivity of 1‐(8‐Amino‐1‐naphthyl)‐1H‐1,2,3‐triazoles.
Authors: NAGAWA Y. , HONDA K. , NAKANISHI H.
Published: May 2016

The azidonaphthyltriazoles (I), prepared from 1,8‐diazidonaphthalene by cycloaddition with the corresponding acetylenecarboxylates, are hydrogenated and then reductively methylated to form the dimethylamino derivatives (IV).
ChemInform Abstract: Conformational Properties of the THYME Polyethers. The Bis‐THYME Cylinder: A Three‐Dimensional Analogue of 18‐Crown‐6.
Authors: WALBA D. M. , RICHARDS R. M. , HERMSMEIER M. , HALTIWANGER R. C.
Published: May 2016

The title compound (II) is characterized by molecular mechanics calculations and as the free ligand, as the toluene solvate, and as a novel cascade complex (K2(OH2)·(III))2+(PtCl3·DMSO)22‐ by means of crystal structures (space group of (II)·toluene: P1, Z=1 and P21/c, Z=2 for the other two cases).
ChemInform Abstract: Synthesis of α‐Telluro Ketones.
Authors: STEFANI H. A. , COMASSETO J. V. , PETRAGNANI N.
Published: May 2016

The ketones (I) undergo substitution reaction with p‐methoxyphenyltellurium trichloride (II) in refluxing benzene to form the α‐telluro ketone (III).
ChemInform Abstract: Synthesis, Structure, and Properties of 1,1,2,2‐Tetrahalo‐1,2‐digermacyclobut‐3‐ene Derivatives. The First Representatives of a New Class of Heterocycles.
Authors: KOLESNIKOV S. P. , EGOROV M. P. , GAL'MINAS A. M. , STRUCHKOV YU. T. , KREBS A. , NEFEDOV O. M.
Published: May 2016

Reaction of the thiacycloheptyne (I) with the dihalogermylenes (II) or (III) gives the fused digermacyclobutenes (IV).
ChemInform Abstract: Synthesis and Characterization of the Zwitter Ion S2C‐C(NMe2)2; a Transition Metal Induced C‐C Coupling. Complex Chemistry of the Zwitter Ions S2C‐C(NR2)2.
Authors: ZIEGLER M. L. , WEBER H. , NUBER B. , SERHADLE O.
Published: May 2016

The zwitter ion (III), prepared by the title reaction together with the unstable complex (IV), reacts with the Mo complexes (V) or (VIII) to give the dithiocarbamato complex (VIa) or (VIa) together with the novel cationic compound (IXa).
ChemInform Abstract: Multiple Bonds Between Main Group Elements and Transition Metals. Part 51. Alkyne Complexes of Rhenium in Intermediate Oxidation States; Synthesis and Molecular Structure of a Rhenium(V)‐Allylidene Complex.
Authors: HERRMANN W. A. , FISCHER R. A. , HERDTWECK E.
Published: May 2016

The Re(IV) complex (I) undergoes disproportionation on reaction with 2‐butyne (IIIa) to give the allylidene‐Re(V) complex (II) and the alkyne‐Re(III) complex (IVa) (yields given in mg).
ChemInform Abstract: Organyl Complexes of (η5‐Cyclopentadienyl)(triorganophosphane)iron.
Authors: LEHMKUHL H. , MEHLER G. , BENN R. , RUFINSKA A. , SCHROTH G. , KRUEGER C. + , RAABE E.
Published: May 2016

A series of organyliron complexes of the type (I) are prepared either from the corresponding (η5‐cyclopentadienyl)bis(tert‐phosphane)iron chlorides and organomagnesium compounds or from (η5‐cyclopentadienyl)(1,5‐cyclooctadiene)‐FeLi, organic halide, and tert‐phosphane in very different yields.
ChemInform Abstract: The Coordination State of CoCl2 in Propylene Carbonate.
Authors: PILARCZYK M.
Published: May 2016

A solution of CoCl2 in propylene carbonate contains the salt mainly as the complex electrolyte (I).
ChemInform Abstract: Synthesis and Molecular Structure of a Dinuclear Quadruply Bridged Cobalt(II) Compound with a Short Metal‐Metal Bond, Co2((p‐CH3C6H4)NNN(p‐C6H4CH3))4.
Authors: COTTON F. A. , POLI R.
Published: May 2016

The diamagnetic title compound (I) is obtained as its THF solvate (I)·7 THF by 1:2 molar reaction of CoCl2 with the corresponding Li triazenide prepared in situ (THF, ‐78 °C).
ChemInform Abstract: Kinetics of 1,3‐Dipolar Cycloadditions of Dimethylacetylenedicarboxylate to Cobaloxime‐Azide, LCo(DH)2N3, Complexes.
Authors: HSIEH B. T. , TAKACH N. E. , MILOSAVLJEVIC E. B. , NELSON J. H. , KEMMERICH T. , BECK W. , BRESCIANI‐PAHOR N. , RANDACCIO L. , BROWER K. R.
Published: May 2016

The kinetics of the title reactions are studied by IR spectroscopy.
ChemInform Abstract: Metal Complexes as Ligands. Part 14. A New FeCu2 Heterotrinuclear Complex (Fe(Cuprp2en)2(ClO4)2(H2O)2). Definitive Evidence for a cis‐Octahedral Configuration and an Isosceles Triangular Arrangement of Metal Atoms.
Authors: BREWER G. A. , SINN E.
Published: May 2016

The synthesis of the trinuclear title complex (III) is carried out according to literature methods by reacting equimolar amounts of the complex ligand (I) with the iron perchlorate (II) (no yield given).
ChemInform Abstract: Crown Thioether Chemistry. Ruthenium(II) Complexes of 1,4,7‐Trithiacyclononane and 1,5,9‐Trithiacyclododecane.
Authors: RAWLE S. C. , SEWELL T. J. , COOPER S. R.
Published: May 2016

Reaction of (Ru(DMSO)6)(BF4)2 with thioether ligands in MeOH yields the oxidatively and hydrolytically stable complexes (I)‐(V).
ChemInform Abstract: Application of the System Dimethyl Sulfoxide‐Acetic Acid Anhydride in the Oxidation of Carbohydrate α‐Hydroxyphosphonates.
Authors: ZHDANOV YU. A. , UZLOVA L. A. , GLEBOVA Z. I. , MOROZOVA G. M.
Published: May 2016

The α‐phosphorylated L‐xylose (I) is oxidized by dimethyl sulfoxide/ acetic anhydride to give the isomeric enolates E‐ and Z‐(III).
ChemInform Abstract: Direct Synthesis of Pyrrole Nucleosides by the Stereospecific Sodium Salt Glycosylation Procedure.
Authors: RAMASAMY K. , ROBINS R. K. , REVANKAR G. R.
Published: May 2016

Treatment of the pyrroles (I) with sodium hydride yields the corresponding N‐sodium salts which react in situ with the α‐D‐erythro‐pentofuranose derivative (II) to give the pyrrole nucleosides (IIIa) and (IIIb).
ChemInform Abstract: (.+‐.)‐4‐Oxo‐9‐deoxy‐9‐azaprostaglandin I2 Derivatives. Very Stable Prostacyclin Analogs.
Authors: GUZMAN A. , MARTINEZ E. , VELARDE E. , MADDOX M. L. , MUCHOWSKI J. M.
Published: May 2016

Key steps in the synthesis of the title compounds (XII) are the preparation of the amide (III), its transformation to the lactam (IV) by reductive deacylation followed by stereoselective introduction of a hydroxyl group and attachment of the α‐chain to the thiolactam (IX) via formation of a thioether and subsequent Eschenmoser sulfide contraction.
ChemInform Abstract: Deconjugation‐Epimerization Strategy en Route to Avermectin B1a: Problems and Solutions.
Authors: HANESSIAN S. , DUBE D. , HODGES P. J.
Published: May 2016

A method is developed which allows the conversion of Δ2‐4(R)‐avermectin B1a (I) into avermectin B1a (IV), first by deconjugation to 2‐epiavermectin B1a (III) (via the tri‐O‐trimethylsilyl derivative of (I)) and then by partial epimerization in the presence of imidazole.
ChemInform Abstract: X‐Ray Diffraction Studies of Rapidly Quenched Li2O‐SiO2 Glasses
Authors: TAKAHASHI M. , TOYUKI H. , TATSUMISAGO M. , MINAMI T.
Published: May 2016

in the composition range 41‐63 mol% Li2O show the Si‐O distances to increase with increasing Li2O content.
ChemInform Abstract: The Electrochemistry of Molten K2S2O7 + K2SO4 + V2O5 Electrolytes
Authors: FRANKE M. , WINNICK J.
Published: May 2016

in contact with SO2/O2/N2 gas mixtures is investigated by cyclic voltammetry, equilibrium potential techniques, and XRD.
ChemInform Abstract: Rechargeable Manganese Oxide Electrodes. Part 2. Physically Modified Materials.
Authors: WROBLOWA H. S. , GUPTA N.
Published: May 2016

It is demonstrated that physical admixtures of Bi2O3 or PbO impart rechargeable behavior to a variety of manganese oxides, regardless of their chain, tunnel, or layer structure.
ChemInform Abstract: Electrochemical Investigations on the Behavior of Thallous Ions During the Formation of PbSO4.
Authors: BARRADAS R. G. , GIRGIS M.
Published: May 2016

Linear sweep voltammetry and potential step measurements are used to study the process of nucleation and growth of PbSO4 (stationary Pb electrode in H2SO4 solution) in the presence of Tl+ at +22 and ‐20 °C. The initial oxidation kinetics are diffusion controlled.
ChemInform Abstract: Synthesis and Molecular Structure of the First Discrete Rhenium Polysulfide Complex, (Bu4N)(ReS9).
Authors: COTTON F. A. , KIBALA P. A. , MATUSZ M.
Published: May 2016

The title compound, prepared as shown in the scheme, crystallizes in the monoclinic system, space group P21/n, Z=4.
ChemInform Abstract: Rare‐Earth‐Metal Cobalt Phosphides with HoCo3P2‐, Sc5Co19P12‐, and YCo5P3‐Type Structures
Authors: JAKUBOWSKI‐RIPKE U. , JEITSCHKO W.
Published: May 2016

have been prepared by reaction of the elements in a tin flux (850‐920 °C, 1‐2 weeks).
ChemInform Abstract: Preparation of High‐Tc Superconducting Oxides by the Amorphous Citrate Process.
Authors: CHU C. , DUNN B.
Published: May 2016

A citrate‐nitrate solution prepared at room temp. and dehydrated at ∼ 80 °C has been used as precursor material to prepare YBa2Cu3O7‐y.
ChemInform Abstract: High‐Pressure Synthesis and Crystal Structure of Pd8Al21, Pd8Al17Si4, and Pt8Al21.
Authors: RANGE K.‐J. , CHRISTL E. G.
Published: May 2016

The title compounds have been prepared from stoichiometric mixtures of the elements by high‐pressure synthesis in a modified belt‐type apparatus (4 GPa, 1400 °C).
ChemInform Abstract: The Macrocyclic and Cryptate Effect. Part 8. Complex Formation of the Cryptands (222), (222B), (222BB) and (222CC) with Different Cations in Methanol Solutions.
Authors: BUSCHMANN H.‐J.
Published: May 2016

The complexation reactions between the title cryptands (I) and mono‐(Li, Na, K, Rb, Cs, Ag) and bivalent (Ca, Sr, Ba, Pb) cations in methanol solution are studied by potentiometric and calorimetric methods.
ChemInform Abstract: Asymmetric Induction at C(β) and C(α) of N‐Enoylsultams by Organomagnesium 1,4‐Addition/Enolate Trapping.
Authors: OPPOLZER W. , POLI G. , KINGMA A. J. , STARKEMANN C. , BERNARDINELLI G.
Published: May 2016

The 1,4‐addition of alkyl‐Mg chlorides (IV) to conjugated N‐enoylsultames and subsequent enolate trapping with aqueous NH4Cl or MeI (V)/HMPA generates centers of asymmetry with good to excellent π‐face differentiation as demonstrated in the scheme by the conversions shown: (I) → (II) + (III), (I) → (VI) + (VII) + (VIII), (IX) → (X) + (XI), (XII) → (XIII) + (XIV) + (XV).
ChemInform Abstract: A Palladium(II) Catalyst for Oxygenation of Terminal Olefins with Molecular Oxygen.
Authors: HOSOKAWA T. , TAKAHASHI T. , OHTA T. , MURAHASHI S.
Published: May 2016

The terminal olefins (I) are oxidized with oxygen in the presence of a catalyst system consisting of acetoxime, CuCl, and PdCl2 to give the methyl ketones (II).
ChemInform Abstract: Selective Reduction of Ketones with Sodium Borohydride‐Acetic Acid.
Authors: NIEMINEN T. E. A. , HASE T. A.
Published: May 2016

Sodium boranate and acetic acid produce reactive acetoxy borane intermediates which reduce the phenyl ketones (I), yielding the alcohols (II).
ChemInform Abstract: Kinetic Resolution of 4‐Hydroxy‐2‐cyclopentenone by Rhodium‐Catalyzed Asymmetric Isomerization.
Authors: KITAMURA M. , MANABE K. , NOYORI R. , TAKAYA H.
Published: May 2016

The oxohomoenol (I) is isomerized in the presence of an optically active Rh(I) binaphthyldiphosphine complex to form cyclopentane‐1,3‐dione (II) via the corresponding enol.
ChemInform Abstract: Preparation of 1,2‐Diarylethylenediamines by Aminative Reductive Coupling of Aromatic Aldehydes with Low‐Valent Titanium Reagents.
Authors: BETSCHART C. , SEEBACH D.
Published: May 2016

The imine (I) (from benzaldehyde) reacts by reductive coupling in the presence of a Ti(0) reagent prepared in situ to yield the rac. ethylenediamine (II).
ChemInform Abstract: Simple Preparation of α‐Acyl α‐Arylthio Oximes (N‐Hydroxy‐2‐oxoalkanimidothioates): Ambident Reactivity of α‐Nitro Ketones.
Authors: JUNG M. E. , GROVE D. D. , KHAN S. I.
Published: May 2016

The acylimidazoles (II) react with the nitronate (I) to produce the α‐nitro ketones (III) which form the thioketals (V) by BF3‐catalyzed reaction with thiophenol (IV).
ChemInform Abstract: Desilylative Pummerer‐Like Rearrangement of α‐Trimethylsilyl‐Substituted Sulfoxide and Sulfides: Formation of α‐Acyloxy and α‐Halogeno Sulfides.
Authors: ISHIBASHI H. , NAKATANI H. , MARUYAMA K. , MINAMI K. , IKEDA M.
Published: May 2016

The aryl trimethylsilylmethyl sulfoxides (I) react with trifluoroacetic anhydride (II) to give the aryl trifluoroacetoxymethyl sulfides (III) via rearrangement and desilylation.
ChemInform Abstract: Catalytic Carbopalladation of ω‐Methylenebicyclo(n.1.0)alkanes.
Authors: DONALDSON W. A. , BRODT C. A.
Published: May 2016

The ω‐methylenebicycloalkanes (I) undergo catalytic carbopalladation and nucleophilic addition reaction with iodobenzene (II) in the presence of sodium diethyl malonate and a Pd(0) complex via cleavage of the inner bond.
ChemInform Abstract: Dissymmetry of Certain Substituted Dipyridotetraazapentalenes.
Authors: PEREIRA D. E. , CLAUSON G. L. , LEONARD N. J.
Published: May 2016

The tetracyclic dipyridotetraazapentalene (IVa) with a "bay region" is a known compound, which is planar.
ChemInform Abstract: Formation and Structure of the Bis(trimethylphosphine)nonahydrohexaboron(1+) Cation.
Authors: KAMEDA M. , KODAMA G.
Published: May 2016

The title cation (II) is obtained by abstracting a hydride ion from the belt‐shaped (I) by reaction with the trityl cation in a 1:1 molar ratio in CH2Cl2 at ‐80 °C. Its structure is discussed by means of 1H, 11B and 31P NMR spectroscopy and found to be similar to that of B6H10·PMe3 or B6H1‐1, which are basal‐bridged square pyramids.
ChemInform Abstract: Synthesis, Reactivity, Kinetics, and Photochemical Studies on Tetrakis(μ‐pyrophosphito)diplatinate(II) and Dihalotetrakis(μ‐pyrophosphito)diplatinate(III) Complexes. Comparison of the Substitution Mechanisms of the Diplatinum(III) Complexes with Those of Monomeric Platinum(II) and Platinum(IV) Compounds.
Authors: BRYAN S. A. , DICKSON M. K. , ROUNDHILL D. M.
Published: May 2016

The pyrophosphito‐bridged diplatinum(II) complex (I) obtained from K2PtCl4 and phosphorous acid reacts with halogens X2 with oxidative addition to give the diplatinum(III) complexes (II).
ChemInform Abstract: Adriadysiolide, the First Monoterpenoid Isolated from a Marine Sponge.
Authors: MANCINI I. , GUELLA G. , GUERRIERO A. , BOLDRIN A. , PIETRA F.
Published: May 2016

The title compound (I) is isolated from a Dysidea species.
ChemInform Abstract: Synthesis of Unsaturated Carbonyl Compounds via the Chromium‐Mediated Allylic Oxidation by 70% tert‐Butyl Hydroperoxide.
Authors: MUZART J.
Published: May 2016

The unsaturated steroids (Ia) ‐ (If) are oxidized in the allylic position with chromium trioxide/tert‐butyl hydroperoxide to give the oxo derivatives (II), together with minor amounts of the epoxides (III).
ChemInform Abstract: A Novel Approach to Estranes by an Intramolecular Double Michael Reaction.
Authors: IHARA M. , TAKAHASHI T. , SHIMIZU N. , ISHIDA Y. , SUDOW I. , FUKUMOTO K. , KAMETANI T.
Published: May 2016

The ketonediene ester (II), synthesized from the bicyclononenone (I), is cyclized to give a mixture of the isomeric steroid esters (IIIa) ‐ (Va).
ChemInform Abstract: 3‐Halovinylglycines. Efficient Irreversible Inhibitors of E. coli Alanine Racemase.
Authors: THORNBERRY N. A. , BULL H. G. , TAUB D. , GREENLEE W. J. , PATCHETT A. A. , CORDES E. H.
Published: May 2016

The syntheses of the D‐, L‐ and racemic chlorovinylglycines (IV) and of the racemic fluorovinylglycine (VIII) are described; optical resolution of (VIII) is achieved.
ChemInform Abstract: Asymmetric Synthesis of Isoquinoline Alkaloids.
Authors: MEYERS A. I. , DICKMAN D. A. , BOES M.
Published: May 2016

Reaction of the isoquinoline (I) with the formamidine (II) yields the chiral auxiliary (III).
ChemInform Abstract: Acyclic Nucleotide Analogues. Part 2. Synthesis of Potential Prodrugs and Metabolites of 9‐(S)‐(3‐Hydroxy‐2‐phosphonylmethoxypropyl)adenine.
Authors: ROSENBERG I. , HOLY A.
Published: May 2016

Reaction of the phosphonate (S)‐(Ia) with DCC affords the cyclic phosphonate (S)‐(II) (isolated as sodium salt (s.s); 89%); the racemate of (II), which is alternatively obtained (s.s; 97%) from the chloromethane phosphonyl compound (Ic), gives the methyl ester (IVa) on methylation.
ChemInform Abstract: 2‐Deoxy‐2‐fluoroglucosides: A Novel Class of Mechanism‐Based Glucosidase Inhibitors.
Authors: WITHERS S. G. , STREET I. P. , BIRD P. , DOLPHIN D. H.
Published: May 2016

Incubation of A. faecalis β‐glucosidase with (Ia) results in a rapid time‐dependent loss of enzyme activity.
ChemInform Abstract: Sintering TiO2 in HCl Atmospheres.
Authors: READEY M. J. , READEY D. W.
Published: May 2016

In the temp. range 1000‐1300 °C, sintering of TiO2 in HCl results in considerably reduced densification compared to sintering in air.
ChemInform Abstract: High Pressure Behavior of Mixed Calcium and Cobalt Orthophosphates, Ca3‐xCox(PO4)2, 0.4 < x ≤ 3.
Authors: THEODORET THEODORET , LENZI J. , ROUX P. , BONEL G. , LENZI M. , DECHAMBRE G.
Published: May 2016

High pressure (55 kbar) treatment at 900 °C of the title orthophosphates leads to the formation of three phases.
ChemInform Abstract: Solid‐State High‐Resolution NMR Studies of Silicic Acids. Part 3. Solid‐State High‐Resolution 29Si NMR Studies of Synthetic Highly Siliceous Silicic Acid Hydrates.
Authors: HEIDEMANN D. , SCHWIEGER W. , BERGK K.‐H.
Published: May 2016

Three synthetic silicic acid hydrates, rich in silicon, are obtained by cation exchange reactions from the synthetic sodium silicate hydrates ilerite, magadiite, and kenyaite.
ChemInform Abstract: Preparation, Crystal Structure, and Thermal Behavior of Potassium Ozonide.
Authors: SCHNICK W. , JANSEN M.
Published: May 2016

Gram amounts of KO3 can be prepared by reaction of gaseous ozone/oxygen mixtures (2 vol.% O3) with KO2 in a temp.‐controlled (+10 to ‐50 °C) fluidized bed reactor followed by extraction with liquid ammonia (100% yield based on KO2).
ChemInform Abstract: Ligand Substituent Contributions to the Rotational Strengths in Cyano(ethylenediamine‐N,N,N′‐triacetato)cobaltate(III) Type Complexes. Crystal Structures of Rb‐(‐)546‐cis‐eq‐(Co(ed3a)CN)·2 H2O and K‐(‐)546‐cis‐eq‐(Co(hed3a)CN)·1.5 H2O
Authors: RADANOVIC D. J. , TRIFUNOVIC S. R. , BAUSE D. E. , MARICONDI C. , ABOLA J. E. , DOUGLAS B. E.
Published: May 2016

(CD spectra of complexes (I) and (II); X‐ray structure analysis and abs.
ChemInform Abstract: A Convenient Catalytic System of Potassium Carbonate and Alkanol: The Michael Addition and Carbonyl Additions Reactions of Imine Compounds.
Authors: ZHON C. , CHEN D. , JIANG Y.
Published: May 2016

The α‐imino esters (Ia) ‐ (Id) undergo Michael addition reaction with the activated olefins (II) in the presence of potassium carbonate and alcohols to produce the bisadducts (III) or the monoadducts (IV) and (V).
ChemInform Abstract: Reaction of Diacetylenic Compounds with Benzyl Azide. Part 3. Cycloaddition of Benzyl Azide to Terminal, Non‐Conjugated Diynes.
Authors: VERESHCHAGIN L. I. , BOL'SHEDVORSKAYA R. L. , MAKSIKOVA A. V. , SEREBRYAKOVA E. S. , KOZYREV S. V. , BRATILOV B. I. , PROIDAKOV A. G.
Published: May 2016

The non‐conjugated terminal diynes (Ia)‐(If) contain the electron accepting or electron donating groups Y. The reaction of these diynes with benzyl azide (II) is investigated.
ChemInform Abstract: (2 + 2) Cycloaddition of Trichloroacetyl Isocyanate to Glycals.
Authors: CHMIELEWSKI M. , KALUZA Z.
Published: May 2016

Reaction of the glycals (I) with trichloroacetyl isocyanate (II) yields the (2 + 2) cycloadducts (III), the (4 + 2) cycloadducts (IV), and in some cases the N‐acyl amides (V).
ChemInform Abstract: A New, Efficient Approach to α,β‐Unsaturated Ketones and β‐Hydroxy Ketones from 4,5‐Dihydroisoxazoles.
Authors: KWIATKOWSKI S.
Published: May 2016

Methylation of the 4,5‐dihydroisoxazoles (I) yields the 4,5‐dihydroisoxazolium methylsulfates (III) which are cleaved on treatment with sodium nitrite, forming the N‐nitroso derivatives (IV).
ChemInform Abstract: Substituent Effect Studies on the Thermal (1,5)‐Sigmatropic Hydrogen Shifts of Vinylallenes.
Authors: SHEN G.‐Y. , TAPIA R. , OKAMURA W. H.
Published: May 2016

Reaction of the propargyl alcohols (I) with phenylsulfenyl chloride (II) yields the two diastereomeric vinylallene sulfoxides (III) and (IV).
ChemInform Abstract: A Very Enantioselective Photodeconjugation of α,β‐Unsaturated Esters.
Authors: PIVA O. , HENIN F. , MUZART J. , PETE J.‐P.
Published: May 2016

Photochemical deconjugation of the α,β‐unsaturated esters (I) yields the β,γ‐unsaturated derivatives (II).
ChemInform Abstract: UV‐Laser Photochemistry: Diffusion‐Controlled Trapping of Cyclic 1,3‐Diradicals by Molecular Oxygen. Conformational Effects on Triplet Lifetimes.
Authors: ADAM W. , HOESSEL P. + , HUEMMER W. + , PLATSCH H. , WILSON R. M.
Published: May 2016

From O2 trapping experiments in solvents of different viscosity it is estimated that the lifetime of the diradical (IIa) falls in the range 100 ±30 ns; diffusion control holds for the trapping of the triplet radicals (IIa) by O2, provided that the molecular diffusion constants and not the macroscopic viscosities are employed in estimating the rate constants.
ChemInform Abstract: Reduction of Amides Containing Polyfluoroalkyl Groups.
Authors: YAMANAKA H. , TAKAGAMI Y. , KUWABARA M. , FUKUNISHI K. , NOMURA M.
Published: May 2016

The reduction of the polyfluorinated amides (I) with various reducing reagents is investigated.
ChemInform Abstract: Stereoselective SN2′ Additions to Chiral Acyclic Vinyloxiranes.
Authors: MARSHALL J. A. , TROMETER J. D.
Published: May 2016

The allylic alcohol (I) is epoxidized and subsequently oxidized to form the chiral epoxy aldehyde (III) which is transformed into the vinylic oxiranes (IV).
ChemInform Abstract: Selective Carbon Formylation of Cyanoacetanilides.
Authors: MANSOUR T. S.
Published: May 2016

The cyanoacetamides (III), prepared from cyanoacetic acid (I) and the anilines (II), react with methyl formate (IV) in the presence of sodium to produce the α‐hydroxymethylene derivatives (V) after acidic work‐up.
ChemInform Abstract: The Photochemistry of Metanilic Acid: Photoisomerization and Photodegradation.
Authors: LALLY J. M. , SPILLANE W. J.
Published: May 2016

Photolysis of sodium metanilate (I) produces a mixture of the isomers (II) and (III), together with aniline (IV).
ChemInform Abstract: The Synthesis and Chemistry of Azolenines. Part 11. Protonation and Alkylation at the Ring Nitrogen Atom in 3,5‐Diaryl‐2H‐pyrrole‐2,2‐dicarboxylic Esters, and an Unusual Rearrangement in the Reaction with Dimethyl Acetylenedicarboxylate.
Authors: CHUNG M. W. L. , LAI T.‐F. , SAMMES M. P.
Published: May 2016

Reaction of the diesters (Ia)‐(Ic) with the dienophile (II) proceeds with rearrangement of one ester group to give the pyrroles (III); the X‐ray structure of (IIIb) (space group P21/c, Z=4) is reported.
ChemInform Abstract: Action of Hydroxylamine on 1,3‐Dihydro‐1,5‐benzodiazepine‐2‐thiones(ones).
Authors: ESSASSI E. M. , SALEM M. , VIALLEFONT P.
Published: May 2016

The thiones (I) react with hydroxylamine (II) to give the rearrangement products (III).