bluuebunny/crossref_metadata_2025 huggingface dataset:
Perancangan Aplikasi Prediksi Jumlah Pendaftar Siswa Baru Dengan Metode Regresi Linier (Studi Kasus: SMA RK Deli Murni Bandar Baru)
Authors: Lase Novita Ria , Riandari Fristi
Published: March 2021

The problem of the SMA RK Deli Murni Bandar Baru school is to predict how many facilities that need to be provided for new students such as chairs, tables and others. This study discusses the prediction of the number of new student registrants at SMA RK Deli Murni Bandar Baru based on the amount of tuition fees using a simple linear regression method. From a commercial point of view, the use of data mining can be used to handle the explosion of data volumes, using computational techniques can be used to produce information needed which is an asset that can increase the competitiveness of an institution. Prediction is almost the same as classification and estimation, except that in the prediction the value of the results will be in the future. This system can be used to predict the number of applicants in the following year to help the school. The advantage is that this simple linear regression method is very simple so that it is easy to calculate and use. Saves the time needed to solve problems, especially those that are very complex.
Sistem Identifikasi Biometrik Ekpresi Wajah Menggunakan Metode Transformasi Hough
Authors: Sindar Anita , Sitio Arjon Samuel
Published: March 2021

The movement of the eye ball affects the condition of the pupil to dilate to become smaller or vice versa, it indicates a person's mood changes very quickly. The image of the eyeball is not necessarily in accordance with the condition of a person's heart, so it is necessary to analyze the movement of the pupil of the eye. Facial expression using the Hough Transformation Method focuses on the movement of the pupil of the eye. The Hough transform works by looking for the neighbor relationship between pixels using straight line equations to detect lines and circular equations to detect circles. Hough line transform is a technique most commonly used to detect curved objects such as lines, circles, ellipses and parabolas. The detection accuracy of the pupil is influenced by the accuracy of the extraction of the edges of the eye. If the outer circle identification is not detected, Hough Transform will be identified. The segmentation step carried out can identify the pupil circle region with a detection success of 80-85%.
Sistem Pendukung Keputusan Menentukan Tingkat Resiko Penjualan Online Dengan Menggunakan Metode TOPSIS
Authors: Sembiring Yosapat , Hasugian Paska Marto
Published: March 2021

At this time many people have started selling online. Even though only with makeshift items to make online sales, not a few people have succeeded in making these online sales. The TOPSIS method is one of the multicriteria decision-making methods, this method is one that is widely used to complete practical decision making. The more factors that must be considered in the decision making process, the more difficult it will be to make a decision on an issue. identification of research problems is the application of the DSS in determining the level of risk of online sales. This system was built using the PHP programming language with data management using the MySQL database. Rank results 1. Furniture = 0.8062 2.Electronics = 0.5810 3. Fashion = 0.1230
Sistem Pendukung Keputusan Penentuan Tingkat Kecanduan Masyarakat Terhadap Rokok dengan Metode Fuzzy Mamdani
Authors: Marpaung Daniel Andre , Marbun Murni
Published: March 2021

A person's addiction to smoking can be seen from the characteristics of the cigarette addict, including: difficulty controlling the desire to smoke, high appetite, frequent coughing, sleep disturbances, and difficulty concentrating. A person's addiction to cigarettes can have a bad impact on the health of that person. The research used the Fuzzy Mamdani method. The system was built using the Hypertext Preprocessor (PHP) programming language. The database management system uses My Structured Query Language (MYSQL). The criteria for the level of community addiction to cigarettes are cost, smoking frequency, and the environment. This study aims to design a Decision Support System for determining the level of community addiction to smoking and applying the Fuzzy Mamdani method for determining the level of community addiction to cigarettes. So it can be concluded that the person's level of addiction is at number 13 or categorized as CANDU.
Satisfação das expectativas dos stakeholders internos da Universidade 11 de Novembro e suas implicações na qualidade de ensino
Authors: Capita Flaviano Luemba
Published: March 2021

Os constantes pronunciamentos que desprestigiam o ensino superior em Angola interpelam a consciência de todos aqueles que direta ou indiretamente têm vindo a empenhar-se para uma Universidade interventiva e capaz de suscitar uma consciência crítica e de discernimento. A necessidade de contribuir para se inverter o referido quadro incentivou a realização da presente pesquisa que, partindo da teoria da expectativa, que estabelece que o esforço empreendido por um indivíduo depende da capacidade que a recompensa tem em satisfazer a expectativa criada, visou diagnosticar a satisfação das expectativas criadas pelos Stakeholders internos da Universidade 11 de Novembro. Para a coleta de dados, a pesquisa valeu-se do questionário e da análise documental. Os dados foram analisados com o auxílio do SPSS. As análises feitas permitiram concluir que, efetivamente, os Stakeholders internos da UON têm as suas expectativas insatisfeitas ou parcialmente satisfeitas, o que reduz as probabilidades de se alcançar o objetivo de melhoria da qualidade de ensino. Para o efeito, urge a necessidade de uma atitude reativa e proativa por parte dos agentes que intervêm nesse processo, isto é, estudantes, docentes e o Governo, para se mitigarem as implicações negativas pela insatisfação das expectativas dos stakeholders e garantir-se a melhoria da qualidade de ensino.
A música como ferramenta lúdica no ensino de hábitos de higiene
Authors: Pamplona Adriane da Silva , Silva Noemy Silva da , Teles Itamar José Santos , Pinheiro Luiz Marcelo de Lima , Biancalana Adriano , Biancalana Fernanda Simas Correa
Published: March 2021

A música através de seu caráter lúdico, destaca-se como um importante recurso pedagógico capaz de auxiliar na formação de hábitos, atitudes e comportamentos. Nesse sentido, a presente pesquisa objetivou verificar a eficiência da música como ferramenta lúdica na transmissão de conhecimentos sobre as práticas de hábitos de higiene na educação infantil. De modo que, para alcançar os objetivos propostos, a pesquisa desenvolveu-se a partir de três etapas, denominadas de: pré-intervenção – que caracterizou-se por investigar através de questionários, as noções iniciais que as crianças apresentavam em relação aos hábitos de higiene; aplicação da linguagem musical – que abordou as práticas corretas de higienização por meio da música e; pós-intervenção – que consistiu em reaplicar o questionário para avaliar o efeito da música como ferramenta lúdica. Os resultados obtidos, revelaram a eficiência da música na transmissão de conhecimentos sobre as práticas corretas de higienização na educação infantil, uma vez que, após a utilização da linguagem musical, ocorreram mudanças significativas na percepção e aprendizagem das crianças.
Educação Especial e Inclusiva: Apontamentos históricos e legais sobre a formação docente na perspectiva da inclusão no Brasil
Authors: Ribeiro Fernando Da Costa , Silva Shirley Dos Santos , Filho Edmar Fernandes Borges
Published: March 2021

O presente artigo intitulado “educação especial e inclusiva: apontamentos históricos e legais sobre a formação docente na perspectiva da inclusão no Brasil”, aborda a trajetória das políticas educacionais da educação inclusiva no Brasil, tem o objetivo de contribuir com o entendimento sobre como alguns marcos reivindicatórios e legais, se refletem na organização do sistema educacional do país, segundo uma perspectiva direcionada à inclusão. Assim, questionamos como os aspectos históricos e legais da Educação Especial e Inclusiva tem contribuído na formação dos professores? Como problemática dessa pesquisa consideramos que um dos principais entraves para a inclusão está na formação docente. Este trabalho decorre de pesquisa bibliográfica e análise documental. A pesquisa ressalta que os cursos de formação docente envolvam de maneira sistemática, e não pontual, estudos sobre as políticas e estratégias para a Educação Inclusiva. Tanto por meio de disciplinas obrigatórias como através de projetos de extensão, ambos sustentados no binômio teoria e prática, fundamentados nas dimensões ético-pedagógicas e sociais, permitindo a experimentação e a criação de técnicas que adaptem as práticas educativas com a diversidade existente no processo de ensino-aprendizagem nas diversas áreas atendidas na educação especial. Percebemos que os educadores necessitam buscar e dispor de meios e métodos formativos que proporcionem inovação em suas práticas educativas voltadas aos alunos com necessidades educacionais específicas. Nem todo material e técnica servem para todos. Cada pessoa tem um ritmo de aprendizagem próprio, daí a necessidade de o corpo docente encontrar auxílio e aprender a trabalhar de maneira colaborativa. Apesar dos avanços ainda é expressiva a demanda por ampliação de propostas específicas relacionadas à vivência inclusiva dentro e fora da sala de aula.
Imagem do campo escuro, unidade natural e efeito anamórfico
Authors: Aguiar Samuel Ferreira de
Published: March 2021

O presente artigo objetivou demonstrar, experimentalmente, a modelagem da unidade natural interativa utilizando o efeito anamórfico formado em tubo de alumínio, visando provar, por meio dela, a imagem microscópica do campo escuro e seu formato modelado naturalmente. Portanto, trata-se de uma pesquisa bibliográfica de cunho descritivo e qualitativo que possibilitou a identificação da imagem e do formato do campo escuro, visto a provação da sua densidade.
KOREOGRAFI KRIDHA MANGGALA KARYA DWI MARYANI
Authors: RACHMAWATI DEBITA EMY , Bantolo Matheus Wasi
Published: March 2021

This research is a discussion about the dance Kridha Manggala by Dwi Maryani which was created based on the Javanese dance tradition of Surakarta and Poco-Poco dance. The problem in this study was the form and creation of this work.   To discuss the issue using the thought of choreography according to Sal Murgiyanto, the category of contemporary dance based on tradition according to Matheus Wasi Bantolo, the form of the dish using the analysis of Janet Adshead, and the process of creation using thinking of Alma M Hawkins. The methods in this study are descriptive analytic with qualitative data, and use a choreographed approach.The results showed that this work is a work Dwi Maryani showed that there is a combination of two elements that are Java elements and the Poco-Poco. The second combination of this element makes a fierce idea for Dwi Maryani in creating the work of Kridha Manggala. The combination of these two elements can be seen in terms of motion, music, and costumes.  The process of creating this work through stages, viewing, sensing, interning, imagining or imagination, tilling, and forming. Live through the exploration, improvisation, and composition stages. Keywords: Kridha Manggala, Dwi Maryani, choreography.
Analysis of Wakaf and Maqashid Syari'ah Law on the Development of Wakaf Property in Lhokseumawe City
Authors: Nasution Yasir , Abubakar Alyasa’ , Kafrawi
Published: March 2021

The development of waqf assets in the form of adding the function of waqf is a new phenomenon in the problems of Islamic law jurisprudence even in positive law in Indonesia. In national law (positive), Indonesia has regulated this issue with the existence of laws and government regulations regarding waqf both movable and immovable waqf assets, even in its development every property in waqf must have an Deed and / or certificate. Whereas in Islamic jurisprudence, the development of waqf assets in the form of additional functions is one of the problems that can be said to be new, it needs legal conclusions and even has to be seen from various theoretical concepts such as maqashidu sharia. Therefore this research will examine the issue of developing waqf assets based on the Waqf Law and maqashid syari'ah. This research is an empirical legal research using a sociological legal approach, with data collection through documentation and interviews. The results of the research show that the development of waqf assets is permitted according to the law, but with the stipulated conditions, besides that the development of waqf assets is also permissible in Islamic jurisprudence as long as it is solely for reasons in accordance with the concept of maqasidu syari'ah and the point is to seek maslahat.
Analysis of troops groupings in modern local wars and armed conflicts
Authors: Tkachenko Anton , Cherevko Ruslan , Nykytenko Anton , Yvashchuk Aleksandr
Published: March 2021

The results of the analysis of recent military conflicts convincingly show that the forms and methods of the armed forces application are changing and improving. Scientific and technological progress, the rapid development of information technology, the growing role of high-precision weapons, increasing the effectiveness of intelligence, intensive automation of command and control systems change the nature of modern warfare and are having a steady impact on operational arts, including the need to further improve management theory. In modern military conflicts, new trends in the development of an armed warfare have emerged, which affect the construction of the armed forces, the development of forms and methods of their application. At the same time, there are deviations from the classical views on the military operation execution.

The article presents some features of modern conflicts, shows that the main task in modern wars is to gain and maintain information superiority over the enemy through the use of a single information and communication space by the troop’s groupings.
Methods of evaluation of efficiency of logistic operations
Authors: Dachkovskyi Vоlodymyr
Published: March 2021

In accordance with the strategic course chosen by Ukraine in the Armed Forces of Ukraine, the transformation of the management system based on the principles of joint leadership of the defense forces must be completed. The main purpose of the transformation is to ensure the maximum efficiency of the use of heterogeneous forces and means of the Armed Forces of Ukraine in the interests of the tasks. One of the components of the transformation is the transition to a logistics system. The introduction of logistical approaches to the management of material resources aims to provide in the shortest possible time with minimal costs and losses of military formations (units) with material means.

Therefore, the paper proposes a method for evaluating the effectiveness of logistics operations. The initial data are determined in the method at the first stage.

At the second stage, the hierarchy of the logistics system with the subsystems of management bodies, warehouses with material resources, restoration of weapons and military equipment, provision of the material means, transportation, etc. is presented. However, on the example of the subsystem of material support, priority technical means have been identified that will be used to perform logistics operations using the method of analysis of hierarchies.

At the third stage, applying the method of the maximum element, rationally distributed forces and means of logistics for the timely provision of military formations with material means.

At the fourth stage, to avoid threats that arise on the routes of technical means, taking into account the terrain, road conditions, etc. using the method of dynamic programming determined the rational route of maneuvering technical means during the task.

At the fifth stage, using the method of a progressive standard, a comparative analysis and evaluation of technical means involved in the implementation of logistics operations.
Обґрунтування рекомендацій щодо запровадження використання активного вугілля під час тривалого зберігання бронетанкового озброєння та техніки
Authors: Kostiuchenko Serhii , Hudyma Viktor , Ostrovskyi Anatolii , Novikova Iryna
Published: March 2021

Навколишнє середовище є постійно діючим носієм агресивних корозійних реагентів. В цілому воно в себе включає атмосферне повітря, якій складається з азоту, кисню, водню, вуглекислого та інертних парів, газів та тверді частини (пил). Майже всі компоненті впливають на протікання корозійних процесів.

Деталі сучасних машин виготовляють в більшій частині зі сплаві різних металів. Використання сплавів підвищує міцність виробів, покращує їх знос та інші властивості.

Основним видом руйнування металічних виробів є електрохімічна корозія. Для її протікання необхідні електроліт, якій може утворитись на поверхні деталей у вигляді маленьких краплин атмосферної вологи, а також анодні та катодні ділянки. Анодні та катодні ділянки на поверхні деталей з’являються не тільки за рахунок зіткнення різних матеріалів, але й не однакового ступеню обробки поверхонь. Практично мікрогальванопари виникають всюди, де на металі є краплини вологі.

Найбільш ефективно захист машин від корозії забезпечується шляхом утворення на поверхні деталей механічного бар’єру, але об’єктах бронетанкової техніки існує ряд деталей які неможна покривати маслом, а цілий ряд систем (головним образом радіоелектронна апаратура та оптичні прилади) дуже чутливі до впливу атмосфери і не може бути захищеним маслами. Тому знайшли так званий спосіб обробки навколишнього середовища. Прикладом такого способу може служити герметизація танка та осушення повітря всередині з допомогою силікагелю ( SiO2·3Н2О).

Для осушення повітря в середині  використовується силікагель марок МСК та КСМ (кусковий та гранульований), який являє собою висушений гель кремнієвої кислоти.
Diagnóstico das condições higiênico-sanitárias em queijarias: uma revisão
Authors: Simas Jessica do Vale , Amaral Gabriela Vieira do , Santos Damaris Alves dos
Published: March 2021

Os queijos fabricados de forma artesanal podem apresentar uma maior probabilidade de contaminação se forem produzidos com matérias-primas qua não são seguras. Por isso, é importante que as empresas adotem a implementação de Programas de Controle de fabricação e qualidade, para que assim diminua os riscos de contaminação, além de assegurar que ele seja produzido com matéria-prima de qualidade e o processo siga todas as normas vigentes para que se tenha um produto final seguro. Pensando nisso, esta pesquisa teve como finalidade copreender o controle de qualidade e fabricação de queijos, mediante uma revisão bibliográfica. Foram comparados 5 artigos nacionais relacionados às condições higiênico-sanitárias de queijarias em bases de dados como Scielo, PubVet, Portal Legislativo do Ministério da Agricultura, Pecuária e Abastecimento (MAPA), site da Agência Nacional de Vigilância Sanitária (ANVISA) e no Portal da Embrapa e em livros publicados, entre os anos de 2010 e 2020. Essa comparação mostrou que os estabelecimentos, na maioria não possuia quaquer tipo de fiscalização e não executavam as atividades de acordo com a legislação vigente. Com isso, pode-se constatar, que os queijos produzidos eram de baixa qualidade.
Importância da identificação do diagnóstico de enfermagem ao paciente com depressão senil na atenção básica
Authors: Silva Brenda Caroline Martins da , Anjos Ingrid Cristina Siraides dos , Pereira Neto Gabriel dos Santos , Santana Davi Silva , Araújo Jainara de Souza , Alves Dayane Jacqueline da Silva , Lima João Victor Magalhães de , Santos Amanda Caroline Nunes dos , Araújo Maira Roberta Ribeiro , Nascimento Monique Teresa Amoras , Batista Ana Paula Ribeiro , Macedo Luana Silva , Furtado Amanda Beatriz Gomes , Aguiar Viviane Ferraz Ferreira de
Published: March 2021

O objetivo do presente estudo é relatar experiência vivenciada a respeito da identificação dos diagnósticos de enfermagem relacionados à depressão no idoso na Atenção Básica, bem como destacar a importância dos cuidados de enfermagem para a promoção da saúde do idoso. Estudo do tipo relato de experiência, de natureza descritiva, com abordagem qualitativa, realizado por acadêmicos da Universidade Federal do Pará. O estudo foi desenvolvido durante consulta de enfermagem com um idoso, em uma Unidade Básica de Saúde (UBS), localizada no município de Belém-Pa. Utilizou-se a Escala de Depressão Geriátrica e o NANDA para identificação dos diagnósticos de enfermagem. Como resultados a escala de depressão o idoso foi possível classificar como depressão leve. Os diagnósticos resultantes encontrados são: ansiedade, medo, estresse e memória prejudicada. É evidente a importância do diagnóstico de enfermagem na identificação da depressão no idoso, principalmente quando este é frequentador da Unidade Básica de Saúde (UBS), pois esses profissionais poderão utilizar das consultas de enfermagem.
Sentidos e significados no processo de aprendizagem no ensino superior a distância: a atuação do tutor presencial
Authors: Soeiro Aline Fernanda , Cecchin Andréa Forgiarini , Nogueira Vanessa dos Santos
Published: March 2021

O presente estudo busca compreender as possíveis implicações da atuação do tutor presencial nos processos de ensino-aprendizagem discentes, considerando os polos de abrangência do Curso de Pedagogia, entre os anos de 2017 a 2019, no âmbito da Universidade Aberta do Brasil (UAB). Essa pesquisa foi realizada através do estudo desenvolvido no Programa de Mestrado Profissional em Políticas Públicas e Gestão Educacional da Universidade Federal de Santa Maria. Inicialmente, realizou-se a sistematização das normativas legais, procurando entender as principais funções do tutor presencial e como elas vinham sendo desenvolvidas no Curso de Pedagogia UAB/UFSM. Buscou-se perceber, a partir do ponto de vista dos sujeitos da pesquisa como as atribuições desses tutores podem influenciar os processos de ensino-aprendizagem dos estudantes. A investigação, de natureza aplicada, ancorou-se em uma abordagem qualitativa, entrelaçando a consulta a documentos e dados empíricos à escuta dos sujeitos envolvidos diretamente com o curso. A coleta de dados envolveu entrevistas semiestruturadas com tutores presenciais e uma escuta dialógica com estudantes de dois polos atendidos pelo curso. Os dados foram analisados a partir da Análise Textual Discursiva, da qual emergiram três categorias: Percepção dos sujeitos acerca das atividades desenvolvidas pelo tutor presencial; Relações/interações entre os sujeitos implicados nos processos de ensino-aprendizagem em EAD, e influência do tutor presencial nos processos de ensino-aprendizagem. Deste cenário de pesquisa, resultou como produto a criação de um ambiente colaborativo de aprendizagem entre os tutores presenciais do curso, utilizando-se da ferramenta eletrônica Padlet.
Produção de mudas de manjericão (Ocimum basilicum L.) sob efeito de diferentes substratos
Authors: Alves Thatiane Nepomuceno , Carvalho Beatriz Lívero , Guedes Politon Thiago Pereira , Nordi Nicholas Taborda , Aires Eduardo Santana , Oliveira Marcelo Munhoz Venâncio de , Ono Elizabeth Orika , Rodrigues João Domingos
Published: March 2021

O objetivo do estudo foi avaliar os efeitos de diferentes substratos na produção de mudas de cultivares de manjericão (Ocimum basicilicum L.). O delineamento experimental foi o inteiramente casualizado, com cinco tipos de substratos (Carolina®, Provaso®, Provaso® + Fibra de coco, Fibra de coco + Turfa e Fibra de coco), sendo estudado em duas cultivares, Basilicão (BS) e Grecco a Palla (GP), com quatro repetições. As avaliações foram realizadas a partir do quinto dia após a emergência. Foi calculado o índice de velocidade de emergência (IVE) e percentual de emergência (E%). A avaliação final foi aos 30 dias após a semeadura (DAS), sendo analisadas as seguintes variáveis: diâmetro do colo (cm), altura da planta (cm), comprimento de raiz (cm), massa seca da parte aérea (g), massa seca de raízes (g), número de folhas, área foliar (cm²) e índice de qualidade de Dickson (IQD). Observou-se que para as duas cultivares BS e GP o substrato Carolina® foi o que proporcionou maior porcentagem de emergência, assim como o menor tempo médio de emergência. Para altura, diâmetro do coleto, número de folhas e área foliar, observou-se, nas duas cultivares, que os substratos, Fibra de coco® e Fibra de coco + Turfa foram menores. Para comprimento de raiz, Fibra de coco foi superior para BS e Fibra de coco + turfa para GP. Levando em consideração todas as características morfológicas analisadas, na cv. BS o Provaso® e Fibra de coco foram os melhores; para a cv. GP foi o Fibra de coco + turfa.
Reduction in Enteroccocus faecalis counts produced by three file systems in severely curved canals
Authors: Nascimento Wayne Martins , Limoeiro Ana Grasiela da Silva , Moraes Mariana Montagner , Campos Danilo De Luca , Drumond João Paulo , Maeda Walber , Soares Adriana de Jesus , Prado Marina Carvalho , Frozoni Marcos
Published: March 2021

Aim: This study evaluated the effectiveness of the mechanical reduction of intracanal bacteria produced by the endodontic systems Reciproc Blue (VDW GmbH), XP-Endo Shaper (FKG Dentaire) and ProTaper Next (Dentsply Sirona Endodontics) in severely curved canals by culture analysis. Methodology: Fifty severely curved mesiobuccal canals of mandibular molars were selected and instrumented. Following this, six specimens were selected as control, while 44 canals were contaminated with Enterococcus faecalis strains (ATCC 29212). Specimens were incubated for 21 days at 37 ºC. Then, contaminated specimens were randomly divided into 3 groups (n=14): ProTaper Next (G1), XP-Endo Shaper (G2) and Reciproc Blue (G3). Control Group: Six non-contaminated canals were prepared with one of the 3 file systems (n=2). Microbial samples were obtained before (S1) and after root canal preparation (S2). Two roots were observed using scanning electron microscopy to verify biofilm formation.  Quantitative culture analyses of intracanal E. faecalis reduction was performed using CFUs, and the Wilcoxon test was used for intragroup analysis, and intergroup analysis was performed using Kruskal-Wallis test. The level of significance for all analyses was set at P < .05. Results: All systems presented effective bacterial reduction (p<0.05), but still had bacterial growth. ProTaper Next displayed the highest E. faecalis reduction (P<0.05), while XP-Endo Shaper and Reciproc Blue systems presented similar results (P>0.05). ProTaper Next showed the greatest antibacterial action when compared to the XP-Endo Shaper and Reciproc Blue systems. Conclusion: No instrumentation system rendered root canals completely free from bacteria.
Educação Superior Indígena na perspectiva da Interculturalidade
Authors: Nascimento Cassandra Augusta Rodrigues , Souza Érica de Souza e , Pereira Laura Belem , Simas Hellen Cristina Picanço
Published: March 2021

Este artigo objetiva contribuir para o debate acerca da Educação Superior na formação de professores indígena na perspectiva da interculturalidade no Brasil, como projeto de resistência ao modelo colonialista eurocêntrico, visando a construção de uma epistemologia que dialogue com os povos indígenas na sua diversidade no contexto Latino Americano, Pan-Amazonico e brasileiro. Trata-se de um estudo de cunho bibliográfico e documental tendo como base metodológica a abordagem quanti-qualitativa. Os resultados indicam que a Educação Superior indígena na territorialidade brasileira é fruto de lutas históricas no campo das políticas públicas por reconhecimento e direitos, tem contribuído na reafirmação de identidades étnicas e no diálogo contínuo entre saberes locais e universais na formação de professores. Entretanto, ainda há muitos obstáculos para a efetivação de uma formação docente indígena intercultural, haja vista que nem sempre a interculturalidade tem conseguido dar conta da complexidade de pensar a formação de professores marcada fortemente pelo modelo colonialista e pelas ideologias hegemônicas neoliberais. Contudo, a partir dessas reflexões tecidas, ressalta-se que o momento sócio-histórico necessita do fortalecimento da luta dos povos indígenas na construção de uma educação superior diferenciada, intercultural e bilíngue diante dos retrocessos impostos pela atual política governamental.
UJI KELAYAKAN AHLI MATERI PADA PENGEMBANGAN MEDIA PERMAINAN TRADISIONAL ENGKLEK DIKONSEP GEOMETRI ANAK USIA DINI
Authors: Istiqomah Nurul , Sandra E Ifa Aristia
Published: March 2021

This research and development aims to determine the feasibility level of the material in the traditional early childhood crank game media. The media development method used in this development was adapted from the Thiagarajan 4-D development model. Data collection techniques from the results of a questionnaire or questionnaire. The results of the validation carried out by two material experts are as follows: 1) Conformity with Basic Competence (KD) is 4 with 80% eligibility criteria. 2) Learning aspect is 3.6 with 72% eligibility criteria. 3) Material presentation is 4 with 80% eligibility. So it can be concluded that the material on the traditional crank game media "WORTH" to be presented.
Effect of protein kinase C and protein kinase A inhibitors on contraction of isolated femoral arteries of SHR and Wistar rats
Authors: Bal MS , Paulis L , Zicha J , Kuneš J
Published: March 2021

Alterations of calcium handling and other second messenger
cascades including protein kinase C (PKC) and A (PKA) were
suggested to be responsible for abnormal vascular function in
spontaneously hypertensive rats (SHR). However, the relative
contribution of these pathways to vasoconstriction is still not
completely understood. We investigated the effect of Ro 31-8220
(PKC inhibitor) and H89 (PKA inhibitor) on vasoconstriction
induced by 120 mM KCl or by addition of 10 µM noradrenaline
(NA) in isolated femoral arteries of control Wistar rats and SHR.
Moreover, we investigated these responses in the presence and
absence of Ca2+ ions in the incubation medium in order to assess
the role of calcium influx in these contractions. We observed that
while the vasoconstriction in the presence of calcium was not
different between Wistar and SHR, the difference between
constriction elicited by NA addition in the absence and presence
of external calcium was larger in SHR. The inhibition of PKC had
no effect on constrictions in SHR, but diminished constrictions in
Wistar rats. PKA inhibition slightly enhanced constrictions in
Wistar rats, but reduced them in the presence of calcium in SHR.
We conclude that vasoconstriction elicited by adrenergic
stimulation is more dependent on extracellular calcium influx in
SHR compared to Wistar rats. Moreover, the activation of PKA
contributes to this calcium-dependent vasoconstriction in SHR but
not in Wistar. On the other hand, PKC activation seems to play a
less important role in vasoconstriction in SHR than in Wistar rats.
FENOMENA PERTANIAN DI DESA CELUK BURUAN BALI DALAM MEDIA DOKUMENTER
Authors: Setiawan I Nyoman Anom Fajaraditya , Adnyana I Nyoman Widhi , Aditama Putu Wirayudi
Published: March 2021

AbstrakPertanian sebagai salah satu sektor penting dalam pemenuhan kebutuhan pangan sebenarnya telah memiliki berbagai piranti hukum yang mendukung. Pesatnya pembangunan dan gencarnya pengadaan infrastruktur ternyata bertambah pesat pula alih fungsi lahan-lahan produktif milik petani. Fenomena ini diikuti pula dengan hasil panen dan industri kecil sebagai pendukung perputaran ekonomi kerakyatan yang perlahan mulai menurun. Perancangan dokumenter tentang eksistensi pertanian dan industri pertanian di Celuk Buruan dilakukan untuk membangkitkan kembali semangat agraris pada sektor ini. Pendekatan riset yang dilakukan dengan pengumpulan data secara kualitatif dari informan, perlahan diungkap fenomena pada realitasnya. Didukung proses perancangan dalam merealisasikan dokumenter, riset ini diharapkan dapat memberikan luaran yang semestinya menjadi bahan renungan khalayak. Tidak hanya termotivasi oleh tindakan penyelamatan sektor pertanian, namun mengingatkan kembali bahwa pertanian adalah salah satu garda terdepan dalam pemenuhan kebutuhan manusia terutama pada kondisi sulit saat ini. Media dokumenter ini dapat menjadi suatu edukasi untuk khalayak agar tidak memandang sektor pertanian dengan sebelah mata. Sehingga pada akhirnya perlu diambil tindakan dalam berbagai studi untuk mengkaji beragam hal terkait pertanian untuk strategi tindakan selanjutnya.  Kata Kunci: Bali, Celuk Buruan, dokumenter, pertanian AbstractAgriculture as one of the significant sectors within food commodity has had various supporting legal tools. The rapid development and incessant provision of infrastructure have also rapidly increased the conversion of productive land owned by farmers. This phenomenon followed by yields and the small industry as a supporter of the people's economy that slowly starts to decrease. The documentary design about the agriculture existence and the agricultural industrial sector in Celuk Buruan was carried to revive the spirit of agrarian in this sector. The research approach was performed by collecting data qualitatively from the informants. Slowly the phenomenon is revealed in its reality. Supported by the design process in realizing the documentary, this research is expected to be able to provide an outcome that should be the subject of public reflection. Not only motivated by the act of saving the agricultural sector but reminded that agriculture is one of the frontlines in fulfillment of human needs, especially under current difficult conditions. This documentary media can be an education for society in order not to demean the agricultural sector. Therefore, eventually, it is necessary to take action in various studies to examine multiple matters related to agriculture for further action strategies. Keywords: agriculture, Bali, Celuk Buruan, documentary
S-Layer From Lactobacillus brevis Modulates Antigen-Presenting Cell Functions via the Mincle-Syk-Card9 Axis
Authors: Prado Acosta Mariano , Goyette-Desjardins Guillaume , Scheffel Jörg , Dudeck Anne , Ruland Jürgen , Lepenies Bernd
Published: March 2021

C-type lectin receptors (CLRs) are pattern recognition receptors that are crucial in the innate immune response. The gastrointestinal tract contributes significantly to the maintenance of immune homeostasis; it is the shelter for billions of microorganisms including many genera of Lactobacillus sp. Previously, it was shown that host-CLR interactions with gut microbiota play a crucial role in this context. The Macrophage-inducible C-type lectin (Mincle) is a Syk-coupled CLR that contributes to sensing of mucosa-associated commensals. In this study, we identified Mincle as a receptor for the Surface (S)-layer of the probiotic bacteria Lactobacillus brevis modulating GM-CSF bone marrow-derived cells (BMDCs) functions. We found that the S-layer/Mincle interaction led to a balanced cytokine response in BMDCs by triggering the release of both pro- and anti-inflammatory cytokines. In contrast, BMDCs derived from Mincle−/−, CARD9−/− or conditional Syk−/− mice failed to maintain this balance, thus leading to an increased production of the pro-inflammatory cytokines TNF and IL-6, whereas the levels of the anti-inflammatory cytokines IL-10 and TGF-β were markedly decreased. Importantly, this was accompanied by an altered CD4+ T cell priming capacity of Mincle−/− BMDCs resulting in an increased CD4+ T cell IFN-γ production upon stimulation with L. brevis S-layer. Our results contribute to the understanding of how commensal bacteria regulate antigen-presenting cell (APC) functions and highlight the importance of the Mincle/Syk/Card9 axis in APCs as a key factor in host-microbiota interactions.
Iripin-3, a New Salivary Protein Isolated From Ixodes ricinus Ticks, Displays Immunomodulatory and Anti-Hemostatic Properties In Vitro
Authors: Chlastáková Adéla , Kotál Jan , Beránková Zuzana , Kaščáková Barbora , Martins Larissa Almeida , Langhansová Helena , Prudnikova Tatyana , Ederová Monika , Kutá Smatanová Ivana , Kotsyfakis Michail , Chmelař Jindřich
Published: March 2021

Tick saliva is a rich source of pharmacologically and immunologically active molecules. These salivary components are indispensable for successful blood feeding on vertebrate hosts and are believed to facilitate the transmission of tick-borne pathogens. Here we present the functional and structural characterization of Iripin-3, a protein expressed in the salivary glands of the tick Ixodes ricinus, a European vector of tick-borne encephalitis and Lyme disease. Belonging to the serpin superfamily of protease inhibitors, Iripin-3 strongly inhibited the proteolytic activity of serine proteases kallikrein and matriptase. In an in vitro setup, Iripin-3 was capable of modulating the adaptive immune response as evidenced by reduced survival of mouse splenocytes, impaired proliferation of CD4+ T lymphocytes, suppression of the T helper type 1 immune response, and induction of regulatory T cell differentiation. Apart from altering acquired immunity, Iripin-3 also inhibited the extrinsic blood coagulation pathway and reduced the production of pro-inflammatory cytokine interleukin-6 by lipopolysaccharide-stimulated bone marrow-derived macrophages. In addition to its functional characterization, we present the crystal structure of cleaved Iripin-3 at 1.95 Å resolution. Iripin-3 proved to be a pluripotent salivary serpin with immunomodulatory and anti-hemostatic properties that could facilitate tick feeding via the suppression of host anti-tick defenses. Physiological relevance of Iripin-3 activities observed in vitro needs to be supported by appropriate in vivo experiments.
Impact of Oseltamivir Treatment on Influenza A and B Virus Dynamics in Human Volunteers
Authors: Hooker Kyla L. , Ganusov Vitaly V.
Published: March 2021

Influenza viruses infect millions of humans every year causing an estimated 400,000 deaths globally. Due to continuous virus evolution current vaccines provide only limited protection against the flu. Several antiviral drugs are available to treat influenza infection, and one of the most commonly used drugs is oseltamivir (Tamiflu). While the mechanism of action of oseltamivir as a neuraminidase inhibitor is well-understood, the impact of oseltamivir on influenza virus dynamics in humans has been controversial. Many clinical trials with oseltamivir have been done by pharmaceutical companies such as Roche but the results of these trials until recently have been provided as summary reports or papers. Typically, such reports included median virus shedding curves for placebo and drug-treated influenza virus infected volunteers often indicating high efficacy of the early treatment. However, median shedding curves may be not accurately representing drug impact in individual volunteers. Importantly, due to public pressure clinical trials data testing oseltamivir efficacy has been recently released in the form of redacted PDF documents. We digitized and re-analyzed experimental data on influenza virus shedding in human volunteers from three previously published trials: on influenza A (1 trial) or B viruses (2 trials). Given that not all volunteers exposed to influenza viruses actually start virus shedding we found that impact of oseltamivir on the virus shedding dynamics was dependent on (i) selection of volunteers that were infected with the virus, and (ii) the detection limit in the measurement assay; both of these details were not well-articulated in the published studies. By assuming that any non-zero viral measurement is above the limit of detection we could match previously published data on median influenza A virus (flu A study) shedding but not on influenza B virus shedding (flu B study B) in human volunteers. Additional analyses confirmed that oseltamivir had an impact on the duration of shedding and overall shedding (defined as area under the curve) but this result varied by the trial. Interestingly, treatment had no impact on the rates at which shedding increased or declined with time in individual volunteers. Additional analyses showed that oseltamivir impacted the kinetics of the end of viral shedding, and in about 20–40% of volunteers that shed the virus treatment had no impact on viral shedding duration. Our results suggest an unusual impact of oseltamivir on influenza viruses shedding kinetics and caution about the use of published median data or data from a few individuals for inferences. Furthermore, we call for the need to publish raw data from critical clinical trials that can be independently analyzed.
Paving the Way Toward Distinguishing Fallers From Non-fallers in Bilateral Vestibulopathy: A Wide Pilot Observation
Authors: Herssens Nolan , Dobbels Bieke , Moyaert Julie , Van de Berg Raymond , Saeys Wim , Hallemans Ann , Vereeck Luc , Van Rompaey Vincent
Published: March 2021

Patients with bilateral vestibulopathy (BVP) present with unsteadiness during standing and walking, limiting their activities of daily life and, more importantly, resulting in an increased risk of falling. In BVP patients, falls are considered as one of the major complications, with patients having a 31-fold increased risk of falling compared to healthy subjects. Thus, highlighting objective measures that can easily and accurately assess the risk of falling in BVP patients is an important step in reducing the incidence of falls and the accompanying burdens. Therefore, this study investigated the interrelations between demographic characteristics, vestibular function, questionnaires on self-perceived handicap and balance confidence, clinical balance measures, gait variables, and fall status in 27 BVP patients. Based on the history of falls in the preceding 12 months, the patients were subdivided in a “faller” or “non-faller” group. Results on the different outcome measures were compared between the “faller” and “non-faller” subgroups using Pearson's chi-square test in the case of categorical data; for continuous data, Mann–WhitneyUtest was used. Performances on the clinical balance measures were comparable between fallers and non-fallers, indicating that, independent from fall status, the BVP patients present with an increased risk of falling. However, fallers tended to report a worse self-perceived handicap and confidence during performing activities of daily life. Spatiotemporal parameters of gait did not differ between fallers and non-fallers during walking at slow, preferred, or fast walking speed. These results may thus imply that, when aiming to distinguish fallers from non-fallers, the BVP patients' beliefs concerning their capabilities may be more important than the moderately or severely affected physical performance within a clinical setting. Outcome measures addressing the self-efficacy and fear of falling in BVP patients should therefore be incorporated in future research to investigate whether these are indeed able to distinguish fallers form non-fallers. Additionally, information regarding physical activity could provide valuable insights on the contextual information influencing behavior and falls in BVP.
Latent Anti-nutrients and Unintentional Breeding Consequences in Australian Sorghum bicolor Varieties
Authors: Hodges Hayden E. , Walker Heather J. , Cowieson Aaron J. , Falconer Robert J. , Cameron Duncan D.
Published: March 2021

Modern feed quality sorghum grain has been bred to reduce anti-nutrients, most conspicuously condensed tannins, but its inclusion in the diets of monogastric animals can still result in variable performance that is only partially understood. Sorghum grain contains several negative intrinsic factors, including non-tannin phenolics and polyphenols, phytate, and kafirin protein, which may be responsible for these muted feed performances. To better understand the non-tannin phenolic and polyphenolic metabolites that may have negative effects on nutritional parameters, the chemical composition of sorghum grain polyphenol extracts from three commercial varieties (MR-Buster, Cracka, and Liberty) was determined through the use of an under-studied, alternative analytical approach involving Fourier-transform infrared (FT-IR) spectroscopy and direct ionization mass spectrometry. Supervised analyses and interrogation of the data contributing to variation resulted in the identification of a variety of metabolites, including established polyphenols, lignin-like anti-nutrients, and complex sugars, as well as high levels of fatty acids which could contribute to nutritional variation and underperformance in monogastrics. FT-IR and mass spectrometry could both discriminate among the different sorghum varieties indicating that FT-IR, rather than more sophisticated chromatographic and mass spectrometric methods, could be incorporated into quality control applications.
Transendoscopic Ventriculocordectomy Using Monopolar Electrosurgical Instrumentation for Conjunctive Treatment of Laryngeal Hemiplegia in Horses: 24 Cases (2017–2019)
Authors: Caspers McKenna K. , Bell Chris D. , Tatarniuk Dane M.
Published: March 2021

Objective: The objective of this study is to evaluate the safety, efficacy, and owner satisfaction following electrosurgical ventriculocordectomy (EVC), in conjunction with prosthetic laryngoplasty, in equine clinical cases affected with left- or right-sided recurrent laryngeal neuropathy.

Methods: Retrospective data analysis of clinical signalment, surgery, athletic outcome, intra- and postoperative complications, and postoperative examinations from clinical cases wherein EVC was performed in conjunction with traditional prosthetic laryngoplasty from one practice. Owners were contacted by phone or email for a follow-up questionnaire.

Results: Twenty-four horses underwent unilateral EVC, performed transendoscopically under sedated restraint, using monopolar electrosurgical instrumentation successfully. One horse experienced excessive intraoperative hemorrhage. No horses demonstrated postoperative complications. Twenty cases had a history of increased airway noise prior to surgery. In 15 of these cases (15/20, 75%), the airway noise was reported as fully improved post-surgery. Eighteen cases had a history of exercise intolerance prior to surgery. In 15 of these cases (15/18; 83%), the exercise intolerance was reported as resolved.

Conclusion: EVC, in conjunction with prosthetic laryngoplasty, can contribute to improvement of RLN symptoms and aid in the effective return to athletic work. Performing transendoscopic ventriculocordectomy with monopolar electrosurgical instrumentation provides comparable clinical outcomes to traditional techniques using a diode laser or direct excision via laryngotomy.
Spatial Proximity of ‘Ataulfo’ to ‘Haden’ Cultivar Increases Mango Yield and Decreases Incidence of Nubbins
Authors: Lucas-García Rodrigo , Rosas-Guerrero Víctor , Alemán-Figueroa Lorena , Almazán-Núñez R. Carlos , Violante-González Juan , Kuk-Dzul José Gabriel
Published: March 2021

Mexico is the leading exporter of mangos worldwide, and ‘Ataulfo’ is one of the most popular cultivars. However, their production has dramatically dropped in recent years due to the high incidence of nubbins. One of the possible causes is the presence of a delayed self-incompatibility found in this cultivar; thus, proximity to compatible cultivars may help to reduce this incidence. Nevertheless, there is a lack of studies that have rigorously tested this hypothesis in this cultivar. For two consecutive years, the present study evaluated the incidence of nubbins, as well as the quality and quantity of commercial fruits of ‘Ataulfo’ trees located at 10, 30, and 50 m away from ‘Haden’ cultivar. Additionally, the yield and economic income of different planting designs were estimated. During both sampling periods, our results clearly indicated that at 10 m away from ‘Haden’ individuals, ‘Ataulfo’ trees presented a lower incidence of nubbins and higher production of commercial fruits, and higher yield and total income per hectare than at 30 or 50 m away from them. These results indicate that planting designs of ‘Ataulfo’ trees located 10 m away from ‘Haden’ will help to satisfy the increasing demand for mangos of this cultivar in the international market.