bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis kesesuaian lahan dan daya dukung ekologis untuk wisata rekreasi pantai di kawasan ekowisata pesisir Deaga, Kabupaten Bolaang Mongondow Selatan (Analysis of land suitability and ecological carrying capacity for beach recreation in the coastal ecotourism area of Deaga, southern Bolaang Mongondow Regency)
Authors: Rauf Aprianto , Djamaluddin Rignolda , Wantasen Adnan S
Published: May 2021

Coastal tourism industry grows very fast, so it is very potential to be used as an alternative business to increase the income and welfare of coastal communities. The development of an optimal tourism area requires good planning and management. This study assesses the suitability of land for coastal recreational tourism activities in Deaga Village, Southern Bolaang Mongondow Regency, by measuring the biophysical and supporting parameters at 8 observation stations on Deaga Beach, as well as the ecological carrying capacity of the environment calculated by considering the ecological potential of visitors. The results of the analysis of the suitability of tourism in Deaga Village are categorized as ‘very suitable’ for beach recreation activities with ecological carrying capacity that can accommodate 113 visitors per day. Thus, the coastal recreation tourism business in Deaga Village is very potential to be developed; and by paying attention to the ecological carrying capacity, this can be sustainable.---Pertumbuhan industri pariwisata pesisir berlangsung sangat cepat sehingga sangat potensial dijadikan alternatif usaha untuk meningkatkan pendapatan dan kesejahteraan masyarakat pesisir. Pengembangan kawasan wisata yang optimal memerlukan perencanaan dan pengelolaan yang baik. Penelitian ini menilai kesesuaian lahan untuk kegiatan wisata rekreasi pantai di Desa Deaga, Kabupaten Bolaang Mongondow Selatan, dengan mengukur parameter biofisik dan penunjang di 8 (delapan) stasiun pengamatan di Pantai Deaga serta daya dukung ekologis lingkungan, yang dihitung dengan mempertimbangkan potensi ekologis pengunjung. Hasil analisis menunjukkan, kesesuaian lahan wisata di Desa Deaga dikategorikan ‘sangat sesuai’ untuk kegiatan rekreasi pantai dengan daya dukung ekologis yang dapat menampung wisatawan 113 orang/hari. Dengan demikian, usaha wisata rekreasi pantai di Desa Deaga sangat potensial dikembang; dan dengan memperhatikan daya dukung ekologis, maka usaha ini dapat berkelanjutan.
The relationship between El Niño Southern Oscillation (ENSO) and oceanographic parameters in North Sulawesi waters
Authors: Lasut Astrid Y. , Patty Wilhelmina , Warouw Veibe , Sondakh Calvyn A. , Bara Robert A. , Luasunaung Alfret , Sumilat Deiske A.
Published: May 2021

Information about oceanographic conditions is important to determine the fertility level of waters. Oceanographic parameters in water can be influenced by global climate factors, one of them is the ENSO (El Niño Southern Oscillation) phenomenon. There have been many studies on the effect of ENSO phenomenon on oceanographic variability, but no studies have been carried out in the waters of North Sulawesi. This study aims to determine the effect of the ENSO phenomenon on the variability distribution of oceanographic parameters in North Sulawesi waters. The data used for this study were Sea Surface Temperature (SST) and chlorophyll-a from the AQUA-MODIS imaging results, wind reanalysis results from ECMWF, and Nino 3.4 index as an indicator of ENSO from NOAA. The data were processed and analyzed using quantitative analysis methods in the form of graphics. The results showed an indirect effect of the ENSO phenomenon on SST parameters and chlorophyll-a. This is because the effect of the ENSO phenomenon occurred in a certain period:  when strong El Niño triggered low temperatures of sea surface and high chlorophyll-a, and when La Niña was strong it triggered high temperatures of sea surface and low chlorophyll-a. Meanwhile, the wind speed pattern showed an insignificant effect because the wind speed was still dominated by the influence of the monsoon pattern.Indonesian title: Hubungan antara El Niño Southern Oscillation (ENSO) dan parameter oseanografi di perairan Sulawesi Utara
PELAYANAN POS PELAYANAN TERPADU DESA BAKUNGTEMNGGUNGAN KEC. BALONGBENDO KAB. SIDOARJO PROVINSI JAWA TIMUR DI ERA PANDEMI
Authors: Kumala Novia Dia , Putri Sukma Asmaning , Febrian Efa Rohmatin , Prathama Ananta
Published: May 2021

Abstract (english)This research discusses the impact of posyandu services in the era of the Covid-19 pandemic for the community in Bakung Village, Temanggungan, Kec. Balongbendo. Where the available services are divided into 3 groups, namely, services for toddlers, pregnant women and the elderly. The purpose of this study was to determine the impact of obstruction of posyandu services for the community caused by the Covid-19 pandemic. To obtain complete data, researchers used qualitative research methods with data collection techniques through observation and interviews. The theory used in this research is descriptive qualitative with hypotheses used subjectively to describe general information. The last stage, draw conclusions by looking for the relationship between the information that has been collected. The results of this study are expected to broaden readers' insights about public services, but it is also hoped that this research can be a reference source for further researchers and as an evaluation material for integrated services in order to further improve the service system during this pandemic and in the future.                                                                 Abstrak (Indonesia)Penelitian ini membahas tentang dampak pelayanan posyandu di era pandemi Covid-19 bagi masyarakat di Desa Bakung Temanggungan Kec. Balongbendo. Dimana pelayanan yang tersedia dibagi menjadi 3 golongan yaitu, pelayanan balita, ibu hamil dan lansia. Tujuan penelitian ini adalah mengetahui dampak dari terhambatnya pelayanan posyandu untuk masyarakat yang disebabkan oleh pandemi Covid-19. Untuk mendapatkan data secara lengkap, peneliti menggunakan metode penelitian kualitatif dengan teknik pengumpulan data melalui observasi dan wawancara. Teori yang digunakan pada penelitian ini adalah deskriptif kualitatif dengan hipotesis yang digunakan secara subjektif untuk menggambarkan informasi secara umum. Tahap terakhir, penarikan kesimpulan dengan mancari hubungan antara informasi yang telah dikumpulkan. Hasil penelitian ini diharapkan untuk menambah wawasan pembaca tentang pelayanan publik, selain itu juga diharapkan agar penelitian ini dapat menjadi sumber referensi untuk peneliti selanjutnya dan sebagai bahan evaluasi untuk pelayanan terpadu agar lebih membaiki sistem pelayanan dimasa pandemi ini dan kedepannya.
Comparison among translational temperatures of

He(1P1o)

,

He(3S1)

, and

Ar(4s[3/2]2o)

in inductively coupled plasmas
Authors: Takada Kosuke , Nishiyama Shusuke , Sasaki Koichi
Published: May 2021

We compared the translational temperatures of

He

(

1

P

1

o

)

,

He

(

3

S

1

)

, and

Ar
(
4
s
[
3

/

2

]

2

o

)

in low-pressure inductively coupled plasmas. We employed laser absorption spectroscopy for measuring the Doppler broadening widths of the transition lines, and they told us the translational temperatures of the three electronic excited states. From the comparison between the temperatures of

He

(

1

P

1

o

)

and

He

(

3

S

1

)

, we confirmed that the metastable 3
S
1 state can work as the probe for the temperature measurement of the ground state helium atoms. We observed higher temperatures for

Ar
(
4
s
[
3

/

2

]

2

o

)

than

He

(

3

S

1

)

in helium–argon mixture plasmas with total pressures less than 80 mTorr. The higher

Ar
(
4
s
[
3

/

2

]

2

o

)

temperature is considered to be due to the selective heating of argon by the charge exchange collision with Ar+.
Strategi Pengembangan Kurikulum 2013 Pendidikan Agama Islam Berbasis Multikultural
Authors: Noor Triana Rosalina , Fitriyah Khoirun Nisa'il
Published: May 2021

Conflicts with ethnic and religious nuances is partly due to the lack of insight into the understanding of cultural diversity. Responding to this situation, Islamic Religious Education is important to develop the multicultural perspective so that the reality of a multicultural society can be accommodated in it. This study used a qualitative approach with the type of case study, with the research location at SMA Kertajaya Surabaya. The informants of this study were the principal and Islamic education teachers, using the method of collecting data through interviews, observation and documentation study. The data that has been obtained are analyzed, interpreted and interpreted qualitatively descriptive. The findings obtained that the formulation of the PAI curriculum that applied was flexible and based on an analysis of the situation faced by the community. The PAI design that is applied considers the multicultural aspects that exist in society by paying attention to the situation of students, and the teachers who carry out learning activities. The strategy used is to include multicultural values such as a sense of justice, love and compassion, mutual respect between teachers and students, between school institutions and elements to the society.
KNOWLEDGE AND ATTITUDE REGARDING SPACING METHODS OF CONTRACEPTION AMONG PRIMIPARA MOTHERS OF KOLHAPUR
Authors: Aurwade Jyoti Dhanpal , Bijapurkar Manisha
Published: May 2021

Background: Almost half of the pregnancies are usually unintended. Inappropriate spacing between pregnancies can lead to maternal and
neonatal complications. Awareness and education plays, a major role in combating this issue. This study was aimed to assess the knowledge and
attitude regarding spacing methods of contraception among primipara mothers of Kolhapur.
Material and methods: The descriptive study was performed on 110 primipara mothers admitted in hospitals of Kolhapur. A pre-validated study
tool consisting of a questionnaire and a Likert attitude scale was used to assess knowledge and attitude of participants. Chi-square and Spearman's
rank correlation test was used to nd the association and correlation between variables.
Results: Good knowledge score was observed in 5.45% participants whereas, average and poor knowledge score found in 70% and 24.55% of
participants respectively. A favorable attitude was noted in 53.6% of mothers and moderately favorable attitudes and unfavorable attitudes were
observed in 43.6% and 2.7% mothers respectively. Asignicant positive correlation was observed between the knowledge score and attitude score
-05 of primipara mothers (r=0.379, P=4.326e ). A signicant association of knowledge score (P<0.01) and attitude score (P<0.01) with the sociodemography of the participants was observed.
Conclusion: Most of the primipara mothers had a favorable attitude regarding spacing methods of contraception but they are lacking in knowledge.
The Socio-demography of the participants was signicantly associated with knowledge and attitude scores.
A COMPARATIVE STUDY OF TADALAFIL & TAMSULOSIN COMBINATION THERAPY VERSUS ALFUZOSIN MONOTHERAPY IN SEXUALLY ACTIVE PATIENTS OF BENIGN PROSTATIC HYPERPLASIA.
Authors: gupta Sandeep , Chatterjee Amvrin , Pal Dilip Kumar
Published: May 2021

BACKGROUND: The patients, suffering from LUTS due to BPH are generally treated with tamsulosin or silodosin .It was found that maximum
patients are suffering from sexual dysfunctions while treating with with those drugs. So in this study we want to observe and compare the
tamsulosin and tadalal combination with alfuzosin monotherapy. These two regimens were chosen because, as per nding of various previous
studies, these two regimens can prevent and as well as treat the sexual adverse effects related to bph and tamsulosin/ silodosin monotherapy
MATERIALAND METHODS: In this study 38 patients were given Tamsulosin (0.4mg) & Tadalal (5mg) xed dose combination therapy and
38 patients were given Alfuzosin (10mg). Symptom scores were assessed with the help of International Prostate Symptom Score (IPS Score),
Quality of Lifestyle Score (QoL Score) and International index of erectile dysfunction score (IIEF 5). Uroowmetry was done to evaluate the
change in Qmax. The evaluation of patients at each group was done at Day 1, 3 month, 6 months.
RESULTS: In this study, patients of both regimens experienced a similar kind of signicant improvement of LUTS, maximum urinary
ow(qmax) and better quality of life over time. In case of erectile dysfunction, patients of tamsulosin and tadalal combination experienced a rapid
improvement, but after 6 months of therapy both groups experienced similar improvement in sexual well being.
CONCLUSION: Alfuzosin is more cost effective and has similar efcacy in comparison to tamsulosin & tadalal combination for treating LUTS
due to BPH in sexually active male patients.
Towards Federated Learning-Enabled Visible Light Communication in 6G Systems
Authors: Naser Shimaa , Bariah Lina , muhaidat sami , Al-Qutayri Mahmoud , Damiani Ernesto , Sofotasios Paschalis C. , Debbah Merouane
Published: May 2021

Visible light communication is envisaged as a promising enabling technology for sixth generation (6G) and beyond networks. It was introduced as a key enabler for reliable massive-scale connectivity, mainly thanks to its simple and low-cost implementation which require minor variations to the existing indoor lighting systems. The key features of VLC allow offloading data traffic from the current congested radio frequency (RF) spectrum in order to achieve effective short-range, high speed, and green communications. However, several challenges prevent the realization of the full potentials of VLC, namely the limited modulation bandwidth of light emitting diodes, the interference resulted from ambient light, the effects of optical diffuse reflection, the non-linearity of devices, and the random receiver orientation. Meanwhile, centralized machine learning (ML) techniques have exhibited great potentials in handling different challenges in communication systems. Specifically, it has been recently shown that ML algorithms exhibit superior capabilities in handling complicated network tasks, such as channel equalization, estimation and modeling, resources allocation, opportunistic spectrum access control, non-linearity compensation, performance monitoring, detection, decoding/encoding, and network optimization. Nevertheless, concerns relating to privacy and communication overhead when sharing raw data of the involved clients with a server constitute major bottlenecks in large-scale implementation of centralized ML techniques. This has motivated the emergence of a new distributed ML paradigm, namely federated learning (FL). This method can reduce the cost associated with transferring the raw data, and preserve clients privacy by training ML model locally and collaboratively at the clients side. Thus, the integration of FL in VLC networks can provide ubiquitous and reliable implementation of VLC systems. Based on this, for the first time in the open literature, we provide an overview about VLC technology and FL. Then, we introduce FL and its integration in VLC networks and provide an overview on the main design aspects. Finally, we highlight some interesting future research directions of FL that are envisioned to boost the performance of VLC systems.
Towards Federated Learning-Enabled Visible Light Communication in 6G Systems
Authors: Naser Shimaa , Bariah Lina , muhaidat sami , Al-Qutayri Mahmoud , Sofotasios Paschalis C.
Published: May 2021

Visible light communication is envisaged as a promising enabling technology for sixth generation (6G) and beyond networks. It was introduced as a key enabler for reliable massive-scale connectivity, mainly thanks to its simple and low-cost implementation which require minor variations to the existing indoor lighting systems. The key features of VLC allow offloading data traffic from the current congested radio frequency (RF) spectrum in order to achieve effective short-range, high speed, and green communications. However, several challenges prevent the realization of the full potentials of VLC, namely the limited modulation bandwidth of light emitting diodes, the interference resulted from ambient light, the effects of optical diffuse reflection, the non-linearity of devices, and the random receiver orientation. Meanwhile, centralized machine learning (ML) techniques have exhibited great potentials in handling different challenges in communication systems. Specifically, it has been recently shown that ML algorithms exhibit superior capabilities in handling complicated network tasks, such as channel equalization, estimation and modeling, resources allocation, opportunistic spectrum access control, non-linearity compensation, performance monitoring, detection, decoding/encoding, and network optimization. Nevertheless, concerns relating to privacy and communication overhead when sharing raw data of the involved clients with a server constitute major bottlenecks in large-scale implementation of centralized ML techniques. This has motivated the emergence of a new distributed ML paradigm, namely federated learning (FL). This method can reduce the cost associated with transferring the raw data, and preserve clients privacy by training ML model locally and collaboratively at the clients side. Thus, the integration of FL in VLC networks can provide ubiquitous and reliable implementation of VLC systems. Based on this, for the first time in the open literature, we provide an overview about VLC technology and FL. Then, we introduce FL and its integration in VLC networks and provide an overview on the main design aspects. Finally, we highlight some interesting future research directions of FL that are envisioned to boost the performance of VLC systems.
One-dimensional DCNN Feature Selective Transformation with LSTM-RDN for Image Classification
Authors: chaorong li , Huang Yuanyuan , HUANG WEI , Qin Fengqing
Published: May 2021

Feature selection and transformation are the important techniques in machine learning field. A good feature selection / transformation method will greatly improve the performance of classification algorithm. In this work, we proposed a simple but efficient image classification method which is based on two-stage processing strategy. In the first processing stage, the one-dimensional features are obtained from image by transfer learning with the pre-trained Deep Convolutional Neural Networks (DCNN). These one-dimensional DCNN features still have the shortcomings of information redundancy and weak distinguishing ability. Therefore, it is necessary to use feature transformation to continue to obtain more distinguishable features. We propose a feature learning and selective transformation network based on Long Short-Term Memory (LSTM) combing ReLU and Dropout layers (called LSTM-RDN) to further process DCNN one-dimensional features. . The verification experiments were conducted on three public object image datasets(Cifar10, Cifar100 and Fashion-MNIST), three fine-grained image datasets(CUB200-2011, Stanford-Cars, FGVC-Aircraft) and a COVID-19 dataset. In the experiments, we used several backbone network models, including AlexNet, VGG16, ResNet18, ResNet101, InceptionV2 and EfficientNet-b0. Experimental results have shown that through feature selective transformation, the recognition accuracy of these DCNN models can significantly exceed the classification accuracies of the state-of-the-art methods.
PulseEdit: Editing Physiological Signals in Facial Videos for Privacy Protection
Authors: Chen Mingliang , Liao Xin , Wu Min
Published: May 2021

Recent studies have shown that physiological signals such as heart beat and breathing can be remotely captured from human faces using a regular color camera under ambient light. This technology, referred to as remote photoplethysmography (rPPG), can be used to collect the physiological status of users who are in front of a camera, which may raise privacy concerns. To avoid the privacy abuse of the rPPG technology, this paper develops PulseEdit, a novel and efficient algorithm that can edit the physiological signals in facial videos without affecting visual appearance and thus protect the user's physiological signal from disclosure. PulseEdit can either remove the trace of the physiological signal in a video or transform the video to contain a target physiological signal chosen by a user. Experimental results show that PulseEdit can effectively edit physiological signals in facial videos and prevent heart rate measurement based on rPPG. It is possible to utilize PulseEdit in adversarial scenarios against rPPG-based visual security algorithms. We present analyses on the performance of PulseEdit against rPPG-based liveness detection and rPPG-based deepfake detection, and demonstrate its ability to circumvent these visual security algorithms and its important role in supporting the design of attack-resilient systems.
EVALUATION OF BIOLOGICAL ANTIMICROBIAL EFFECT OF ALOE VERA ON COLIFORM ISOLATES IN LEACHATE FROM A DUMPSITE
Authors: Olu Joshua , Hajara Oyiza Yusuf , Ikhide Charles Evbomai , Okokoro Henry
Published: May 2021

This study is to evaluate the biological disinfectant ability of Aloe vera (under different conditions and parameters) on coliform isolates from leachate that emanate from a dumpsite.Leachate samplewas subjected to a presumptive test to evaluate the presence of coliforms in them; the positive samples were further subjected to a confirmatory test to identify the thermo-tolerant nature of the coliform. The coliforms were thermo-tolerant Escherichia coli (FTE) and Thermo-tolerant coliform (non E. coli) (FTC) Disinfectant efficacies of Aloe vera (with various condition and parameters) were evaluated on the isolated microorganisms from the leachate samples, using the disc diffusion method. The Aloe vera showed that concentration of the disinfectant matters in its efficacy with 5% storage concentration showing high level of zone of inhibition with the isolated microorganisms. Also the Aloe vera was more effective at a lower pH and storage temperatures of 0, 25 and 35oC.
ПСИХОЛОГО-ПЕДАГОГИЧЕСКАЯ ПОДДЕРЖКА САМОРАЗВИТИЯ ПОДРОСТКОВ В СОЦИАЛЬНО-ПЕДАГОГИЧЕСКОЙ ДЕЯТЕЛЬНОСТИ
Authors: Насурова З.А.
Published: May 2021

В статье раскрывается актуальность темы исследования, рассматривается проблема саморазвития подростков; проанализирован вклад отечественных и зарубежных психологов в исследование данного феномена; рассмотрены основные особенности, присущие подростковому возрасту, которые являются непременными составляющими как успешного саморазвития, так и жизненной самореализации подростков. Из статьи мы узнаем, что подростки ощущают чувство неудовлетворенности от отсутствия понимания, от невостребованности и нереализованности своих возможностей.
Автор в своей работе представляет психолого-педагогическую поддержку как систему социально-психологических и психолого-педагогических способов и методов, способствующих самоопределению личности в ходе формирования ее способностей, ценностных ориентаций и самосознания.
ОЦЕНКА СОСТОЯНИЯ СОСУДИСТО- ТРОМБОЦИТАРНОГО ГЕМОСТАЗА У ПАЦИЕНТОВ С COVID-19 (Обзор литературы)
Authors: Адров А.В. , Бахаева А.В. , Тужиева М.А.
Published: May 2021

Считается, что пациентам с вирусной инфекцией COVID-19 следует контролировать протромбиновое время (ПТВ), концентрацию D-димера, фибриногена и количество тромбоцитов. Повышение концентрации D-димера коррелирует с высокой летальностью, а быстро нарастающая гипофибриногенемия приводит к развитию диссеминированного внутрисосудистого свертывания (ДВС).
ОСНОВНЫЕ ТЕНДЕНЦИИ И ПЕРСПЕКТИВЫ РАЗВИТИЯ МЕДИЦИНЫ СНА: АМЕРИКАНСКИЙ ОПЫТ
Authors: Гантамиров Т.Т.
Published: May 2021

В данной статье представлен научный анализ медицины сна. Выявлены основные тенденции и перспективы ее развития. Активное развитие этой области привело к ее признанию в качестве независимой медицинской специальности Советом по аккредитации последипломного медицинского образования и Американским советом по медицинским специальностям. Однако требование прохождения стипендиальной программы, которое теперь является обязательным для получения сертификата по медицине сна, имело непредвиденные последствия, ограничив приток молодых врачей в данную сферу. В ответ на потенциальную нехватку квалифицированных кадров, с которой сталкивается область медицины сна, совет директоров Американской академии медицины сна разработал всеобъемлющий план по ее развитию за счет расширения стипендиальных программ, изучения новых возможностей обучения медицине сна, создания и развития команды специалистов по сну (с особым упором на привлечение специалистов первичной медико-санитарной помощи). Планы Американской академии медицины сна, кратко изложенные в этой специальной статье, представляют собой усилия по противодействию серьезным кадровым проблемам и превращению их в возможности, которые улучшат как здоровье пациентов, так и качество медицины сна.
AVALIAÇÃO DA FRAGILIDADE E QUALIDADE DE VIDA DE IDOSAS E ANCIÃS PRATICANTES DE EXERCÍCIO FÍSICO
Authors: Andrade Camila Regina Lobato , Silva Claudio Bruno Viana , Ferreira Dayanne da Mota , Segtowick Ana Cristina Isackson , Brito Ana Júlia Cunha , Silva Moises Costa da , Silva Josiana Kely Rodrigues Moreira da , Dias George Alberto da Silva , Dias Biatriz Araújo Cardoso
Published: May 2021

Introdução: O envelhecimento no Brasil tem aumentado nos últimos anos. As mudanças que constituem e influenciam o envelhecimento são complexas, podendo tornar o idoso propenso a desenvolver a condição de fragilidade, com consequente alteração na qualidade de vida. Objetivo: Avaliar a fragilidade e qualidade de vida de idosas e anciãs ativas praticantes de exercício físico. Método. Trata-se de um estudo observacional analítico do tipo transversal, que utilizou uma amostra de 29 participantes, apresentando função cognitiva preservada. Foram avaliados a força muscular, velocidade da marcha, fadiga/exaustão, nível de atividade física e perda de peso não intencional e da qualidade de vida por meio do questionário WHOQOL-OLD. Resultado. Observou-se que 79% (23/29) das participantes da pesquisa eram idosas (60 a 74 anos) com média de idade de 65,09±4,06 anos e que 21% (06/29) eram anciãs (75 a 90 anos) com média de 79,00±1,41 anos. Nas facetas autonomia, atividade, participação social, morte, intimidade e consecutivamente na pontuação geral, as anciãs apresentaram uma tendência para melhor qualidade de vida do que as idosas, porém sem significância estatística. Houve correlação entre a qualidade de vida e a energia auto referida das idosas (p=0,02) demostrando que o nível de energia influencia na qualidade de vida, diferentemente do que observado para as anciãs. Conclusão: As idosas e anciãs não apresentaram síndrome da fragilidade e alteração na qualidade de vida.
El nacionalismo musical mexicano una mirada desde la teoría del campo de Bourdieu
Authors: Serrano Arias Fernando de Jesús , E Gunther Delgado Leonel
Published: May 2021

-
Hepatoprotective activity of Chamaecrista nigricans in Experimental Rats
Authors: Ekambaram Gayathiri  , Madepalli Byrappa Viswanathan
Published: May 2021

An important ethnomedicinal plant Chamaecrista nigricans (Vahl) Greene, widely used for antipyretic, appetite, family planning, fevers, sore throat, wounds and various gastrointestinal disorders including diarrhoea and peptic ulcer. In the present study, acute toxicity and hepatoprotective activity of methanol extract alone were carried out in experimental animals approved by the Institutional Animal Ethics Committee. In acute toxicity studies, there was no mortality in animals when the extracts tested as per OECD guidelines. Regarding hepatoprotective activity, methanol leaf extract significantly reduced the increased level of serum marker enzymes such as ACP, ALP, ALT, AST and Total bilirubin. The protective effect of the methanol extract was also confirmed by histopathological examination which supports that the methanol leaf extract repaired the liver damage caused by CCl4. Thus the present study provides scientific evidence to the extracts of their hepatoprotective potential against liver damage and offers lead for further research in drug development.

Keywords: Ethnomedicine; Chamaecrista Nigricans; Acute Toxicity; Hepatoprotective; Drug Development
Phytochemical and Antioxidant Test of Binahong (Anredera cordifolia (Tenore) Steenis) Leaves Ethanol Extract
Authors: Souhoka Fensia Analda , Kapelle Imanuel Berly Delvis , Sihasale Elisabeth
Published: May 2021

Binahong Anredera cordifolia (Tenore) Steenis leaves contain chemical compounds that can be used as antioxidants. This study aims to examine the phytochemical and antioxidant activity of the ethanol extract of binahong leaves. Binahong leaves were extracted using the maceration method with an ethanol solvent. The phytochemical test showed that the ethanol extract of binahong leaves contained phenolic compounds, flavonoids, alkaloids, and tannins to have potential antioxidants. The antioxidant activity test was carried out using the DPPH method and absorbance measurement with a UV-Vis spectrophotometer at a wavelength of 517 nm. The results showed that the ethanol extract of binahong leaves had strong antioxidant activity, as evidenced by the IC50 value of 87.423 µg/mL.
Ketahanan Hidup Bibit Ikan Mujair (Oreochromis mossambicus) Dan Nilai Parameter Kimiawi Lingkungan Pada Media Pemeliharaan Bioflok Dengan Debris Daluga Sebagai Sumber Karbon
Authors: Moko Emma Mauren , Rattu Ferencia Esananda , Sakul Ernest Hanny , Naharia Orbanus , Yalindua Aser , Rawung Livana Dethris
Published: May 2021

Bioflok adalah teknik budidaya ikan untuk mengelola lingkungan budidaya dengan memanfaatkan mikroorganisme untuk meningkatkan penggunaan pakan dan sisa hasil metabolisme dengan penambahan sumber karbon organik. Penelitian ini bertujuan untuk mengetahui ketahanan hidup bibit ikan mujair (Oreochromis mossambicus) dan nilai parameter kimiawi lingkungan pada media pemeliharaan bioflok dengan debris daluga (Crytosperma merkusii) sebagai sumber karbon. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan 4 perlakuan dan 3 ulangan. Perlakuan yang dilakukan adalah tanpa bioflok, C:N=15, C:N=20, dan C:N=25. Hewan uji ikan mujair dengan panjang rata-rata 5,5 cm di tebar 10 ekor setiap ember. Parameter yang diamati adalah kualitas air yang meliputi suhu, pH, konduktivitas, dan redoks dan Survival Rate (SR) ikan mujair. Dari hasil penelitian diketahui bahwa perlakuan terbaik pada C:N=25 dengan persentase SR tertinggi yaitu, 86,67%. Kualitas air selama penelitian ada pada kondisi optimal di setiap perlakuan.
Kajian Regiokimia Markovnikov Melalui Mekanisme Reaksi Hidrasi Alkuna Terminal pada Etinilestradiol dengan Katalis FeCl3
Authors: Simbolon Hotma Rotua Br. , Rumampuk Rymond Jusuf , Aloanis Anderson Arnold
Published: May 2021

The terminal alkynes hydration reaction on 17α-ethynylestradiol (1) with FeCl3 catalyst mediated by dichloromethane aims to determine the reaction products produced and to conduct a Markovnikov regiochemistry study through the proposed reaction mechanism. The reaction conditions were carried out at a temperature of 50oC (48 hours) and 60oC (19 hours), the separation of the reaction properties was carried out using Gravity Column Chromatography, and the reaction products were identification using by Proton Nuclear Magnetic Resonance (1H-NMR). Here we describe the process of the FeCl3 catalyst forming a coordination complex with the terminal alkyne, which is then addition by nucleophilic water following Markovnikov's regiochemistry to finally produce the product of a methyl ketone, 17α-acetylestradiol (6). The catalyst used is a cationic ligand coordinate, where Fe3+ is a Lewis acid and Cl3- acts as a ligand. The dichloromethane solvent used can also increase the reaction rate.
One of Curious Congenital Midline Abdominal Defects In Newborn: A Giant Omphalozele In A 3 Years-Old Boy
Authors: Bittmann Stefan
Published: May 2021

Omphalocele is one of the congenital abdominal wall defects and specifically refers to an umbilical ring defect in which the abdominal organs protrude in front of the abdominal wall in a thin sac or membrane. Such an abdominal wall defect develops around the third week of pregnancy due to the failure of adhesion between the embryonic lateral abdominal wall components.
HGH and Cartilage
Authors: Slater Gordon
Published: May 2021

Recombinant human growth hormone (rHGH) which plays an important role for remodeling of bone has an effect on cartilage differentiation and regeneration, as well. Herein, we reviewed human growth hormone and its roles on cartilage. We discussed different roles on growth, regeneration, inflammation, cell maturation, and mitotic activity. These findings provide proof of principle that therapeutics based on rHGH can improve treatment for numerous disorders.
A beruházás-lebonyolító szerepe és helye a közbeszerzésekben
Authors: Szabó Kinga
Published: May 2021

A beruházás-lebonyolító az építtető megbízásából az építtetői felelősségi körbe tartozó egyes feladatokat ellátó szervezet, személy. A közbeszerzésekkel való kapcsolata ajánlattevői minőségben, továbbá ajánlatkérői oldalon is megjelenhet. Cikkünk részletesen megvizsgálja a beruházás-lebonyolító jogszabályokból levezethető, valamint a valós beruházási gyakorlatban megjelenő, az építtetőt támogató, közbeszerzésekhez kapcsolódó funkcióit.
Characteristics of Haemophilia Patients: A One-Year Experience from A Tertiary Care Hospital in Bangladesh
Authors: Miah M Morsed Zaman , Rafi Md. Abdur , Hasan Md. Kamrul
Published: May 2021

Haemophilia is one of the most common bleeding disorders globally. Though the prevalence of haemophilia in Bangladesh according to the ‘World Haemophilia Registry’ is ten per million people, the original prevalence would be much higher. There is lack of evidence about the socio-demographic and clinical characteristics of these patients. The objective of the present study was characterization of the haemophilia patients according their socio-demographic condition as well as their disease and treatment related profiles. All the patients who visited the haematology department of Rajshahi Medical College Hospital (RMCH) from May 1, 2019 to April 30, 2020 diagnosed as haemophilia were included in the study. Socio-demographic and clinical data from 74 haemophilia patients were analysed. Among them 72 patients were male. More than two-thirds of the patients were from rural area and belonged to lower socioeconomic status. Total 72 out of 74 patients were suffering from haemophilia A. Severity of the disease was mild 34%, moderate 63% and severe 3%. More than 86% patients reported target joint of bleeding and 78% of them had bleeding in last six months. A total of 73% patients received treatment within past six months of the current visit and all of them received factor concentrates. More than 94% patients received treatment on demand. Under the shed of findings of the present study it is recommended that a funded haemophilia management program and optimum use of prophylactic therapy is necessary to improve the quality of life as well as increase life expectancy of the patients.
Outcome of Diffuse Large B-Cell Lymphoma with First-line Chemotherapy
Authors: Chowdhury Zulfia Zinat , Bahar Tamanna , Rahman Shaila , Haque Salina , Islam A K M Mynul , Ali Mohammad , Rahman Md. Mahbubur
Published: May 2021

Background: Diffuse Large B-Cell Lymphoma (DLBCL), most common Non-Hodgkin Lymphoma (NHL) variety, is an aggressive, fast-growing form comprising up to 40% of all cases globally. Objective: To observe the treatment outcome of different subtypes of Diffuse Large B-Cell Lymphoma (DLBCL) after first-line chemotherapy and also the association with IHC, presenting age, sex, and IPI score with outcome. Methodology: This is a retrospective data analysis included all DLBCL patients registered in the department of Haematology of National Institute of Cancer Research and Hospital (NICRH) between July 2016 to June 2019. Results: Total 188 cases were included in this study and mean age was 48 years with a Standard deviation of 15 years with Male (69.1%) predominance. We divide the cases into three different entities of DLBCL [Germinal Centre B-cell like (GCB), Non-GCB and others (NOS) among them Non-GCB variety was the prevalent (47.3%) one. After first line   chemotherapy 52.1% complete remission with 7% death was observed in overall outcome. There was no significant difference in outcome among different types of DLBCL after chemotherapy based on Han’s algorithm. Rituximab with CHOP has significantly better outcome than CHOP alone arm (p: 0.021). Conclusion: This limited database study of NICRH will help to ascertain the outcome of DLBCL after first-line chemotherapy in Bangladesh.
Pattern of Haematological Malignant Patients Attending OPD in a Tertiary Level Hospital in A Calendar Year
Authors: Farhad Md. Nurul , Islam Gazi Yeasinul , Wasim Mohammad , Biswas Akhil Ranjon , Tompa Tanzia Khanum
Published: May 2021

Background: Hematologic malignancies are of diverse incidence, prognosis, and etiology. Dhaka medical college hospital (DMCH) is a tertiary level hospital and dealing with patients attending from all over the country. We have analyzed data of patients present with hematological malignancy in our Out Patient Department (OPD). As Hematology Dept DMCH deal with patients referred from all over the country, its OPD data represents the picture of whole country. Methods: This is a retro-spective study of OPD patients with hematological malignancy in the department of Hematology of DMCH from January 2018 to December 2018. The diseases were diagnosed on the basis of bone marrow morphology or histopathology (Lymphoma) and or immunophenotyping & molecular genetics. Results: Total 5747 patients were treated in 2018 with the complaints related to hematological malignancy of which 4599 (80%) were old patients and 1148 (20%) were new patients. Among all the treated patients 1420 (24.7%) were female and 4327 (75.3%) were male. Among 1148 new cases 37 were AL(3%), 386 were ALL (34%), 265 were AML(23%), 32 were CLL (3%), 126 were CML (11%), 40 were HL (3%), 18 were MDS (1%), 76 were MM (7%), 168 were NHL (15%). Data shows variation in total number of new patients per month- 83 in January (7.23%), 96 in February (8.36%), 140 in March (12.20%), 98 in April (8.54%), 94 in May (8.19), 89 in June (7.75%), 98 in July (8.54%), 66 in August (5.75%), 99 in September (8.62%), 103 in October (8.97%), 98 in November (8.54%), 84 in December (7.31%) But it does not show any statistical significant frequencies of diseases according to months. Conclusion: We deal a lot of patients with hematological malignancy each year in DMCH. A good portion of them are of ALL because of monthly maintenance of ALL protocols. Analysis of new cases shows ALL, AML, NHL is most common three diseases encounter in OPD. OPD patients’ inflow does not show any significant monthly variation for any of the diseases.
Capital humano e obtenção de informações técnicas na agricultura : perfil e diferenças regionais a partir dos dados do censo agropecuário de 2017
Authors: Conceição Júnia Cristina Péres Rodrigues da
Published: May 2021

O texto tece comentários sobre o desenvolvimento homogêneo da agricultura entre as regições brasileiras por meio da adoção de políticas que levem em consideração as diversidades regionais existentes inclusive no que se refere ao estoque de humano.
TD 2632 - Educação no Meio Rural: diferenciais entre o rural e o urbano
Authors: Pereira Caroline Nascimento , Castro César Nunes de
Published: May 2021

Este trabalho apresenta uma radiografia da educação rural em comparação ao meio urbano brasileiro com objetivo de amparar a discussão e formulação de políticas educacionais para o meio rural. Esse meio padeceu por muitos anos com a ausência de políticas específicas educacionais, em especial desde os anos 1960, quando ocorreu a modernização agrícola no campo. Apesar de algumas políticas implementadas ao longo dos anos, principalmente nos anos 2000, os diferenciais ainda são gritantes entre as duas realidades. Para a radiografia da educação no campo, utilizaram-se os dados mais recentes do censo escolar, Pesquisa Nacional por Amostra de Domicílios (PNAD) e censo demográfico. O trabalho inicia com uma discussão sobre desenvolvimento e políticas públicas educacionais no meio rural, seguida por um breve histórico da educação no campo brasileiro. As seções seguintes apresentam informações socioeconômicas da população rural, considerando renda e escolaridade, o perfil da educação básica brasileira e os resultados do Sistema de Avaliação da Educação Básica (Saeb), com foco nos resultados do meio rural.
TD 2638 - Desenvolvimento da Agricultura de Baixo Carbono no Brasil
Authors: Telles Tiago Santos , Filho José Eustáquio Ribeiro Vieira , Righetto Ana Julia , Ribeiro Marina Ronchesel
Published: May 2021

Em 2009, o Brasil se comprometeu com a redução das emissões de gases de efeito estufa (GEE). Desde então, instituiu-se a Política Nacional sobre Mudança do Clima (PNMC). Em 2010, foi elaborado o Plano Setorial de Mitigação e de Adaptação às Mudanças Climáticas para a Consolidação de uma Economia de Baixa Emissão de Carbono na Agricultura (Plano ABC). Com as ações do Plano ABC buscou-se recuperar pastagens degradadas, expandir a adoção dos sistemas integrados de lavoura-pecuária-floresta, dos Sistemas Agroflorestais (SAFs) e do Sistema Plantio Direto (SPD), difundir a Fixação Biológica de Nitrogênio (FBN), plantar florestas e tratar dejetos animais. Nesse contexto, este estudo tem por objetivo verificar as mudanças no uso da terra, o crescimento da produção agropecuária brasileira e o cumprimento das metas do Plano ABC. A partir dos resultados é possível constatar que os compromissos internacionais acordados pelo Brasil foram cumpridos. A expansão na adoção das tecnologias do Plano ABC atingiu 154% da meta; e a mitigação de CO2, o equivalente a 113% da meta. Todavia, a recuperação de pastagens degradadas e o tratamento de dejetos animais se apresentam como dois dos principais gargalos da questão produtiva e para agricultura de baixa emissão de carbono no Brasil. Em termos de mitigação, é necessário ampliar os investimentos na recuperação de pastagens degradadas e no tratamento de dejetos animais. Em síntese, os indicadores sinalizam que a agropecuária brasileira está cada vez mais centrada na sustentabilidade ambiental e no desenvolvimento de tecnologias de baixa emissão de carbono, que são poupadoras de recursos naturais.
TD 2650- Regulamentação Técnica, Acordos Comerciais e Multilateralismo
Authors: Tironi Luís Fernando
Published: May 2021

A regulamentação técnica ocupa um papel importante no arcabouço normativo do multilateralismo capitaneado pela Organização Mundial do Comércio (OMC). Isso se deve ao seu eventual uso como barreira comercial. O tratamento do tema da regulamentação técnica acompanhou a evolução da normativa dos acordos da OMC, e constitui um dos elementos relevantes ao contexto das indagações que têm surgido sobre a necessidade de ajustes nas normativas da organização. A evolução do multilateralismo foi adaptativa às demandas suscitadas pela emergência dos acordos de preferências bilaterais, plurilaterais e regionais, buscando manter-se fiel aos princípios do livre comércio. Tal perspectiva suscita a pergunta de como a regulamentação técnica será impactada e, contrariamente, como poderá impactar a evolução futura do multilateralismo. O futuro do multilateralismo certamente será influenciado pelos interesses dos três mega polos de poder global: Estados Unidos, China e União Europeia (UE). Em termos da regulamentação técnica, os demais países farão as escolhas ou a combinação de escolhas que melhor atendam seus interesses. Esse trabalho pretende ser um subsídio a essas escolhas.
Narrowband Observations of Comet 46P/Wirtanen during Its Exceptional Apparition of 2018/19. II. Photometry, Jet Morphology, and Modeling Results
Authors: Knight Matthew M. , Schleicher David G. , Farnham Tony L.
Published: May 2021

We report on our extensive photometry and imaging of comet 46P/Wirtanen during its 2018/19 apparition and use these data to constrain the modeling of Wirtanen’s activity. Narrowband photometry was obtained in 9 epochs from 2018 October through 2019 March as well as 10 epochs during the 1991, 1997, and 2008 apparitions. The ensemble photometry reveals a typical composition and a secular decrease in activity since 1991. Production rates were roughly symmetric around perihelion for the carbon-bearing species (CN, C3, and C2), but steeper for OH and NH outbound. Our imaging program emphasized CN, whose coma morphology and lightcurve yielded rotation periods reported in a companion paper (Farnham et al. 2021). Here, we compare the gas and dust morphology on the 18 nights for which observations of additional species were obtained. The carbon-bearing species exhibited similar morphology that varied with rotation. OH and NH had broad, hemispheric brightness enhancements in the tailward direction that did not change significantly with rotation, which we attribute to their originating from a substantial icy grain component. We constructed a Monte Carlo model that replicates the shape, motion, and brightness distribution of the CN coma throughout the apparition with a single, self-consistent solution in principal axis rotation. Our model yields a pole having (R.A., decl.) = 319°, −5° (pole obliquity of 70°) and two large sources (radii of 50° and 40°) centered at near-equatorial latitudes and separated in longitude by ∼160°. Applications of the model to explain observed behaviors are discussed.
Detection of aflatoxin B1 adducts in Mexican women with cervical lesions
Authors: de León-Martínez L. Díaz , López-Mendoza C.M. , Terán-Figueroa Y. , Flores-Ramírez R. , Díaz-Barriga F. , Alcántara-Quintana L.E.
Published: May 2021

Cervical cancer (CC) is one of the most serious threats to the lives of women; co-factors in addition to oncogenic human papillomavirus (HPV) infection may be important in causing CC. Women in Mexico are exposed to dietary aflatoxin B1, a potent carcinogen, which may act as a co-factor, in inducing progression to CC. Scarce studies are addressing environmental risks associated with the development of CC, thus the study aimed to establish a relationship between the presence of AFB1 and the detection of human papillomavirus in the genome of Mexican women. Forty samples from cervical tissue of women infected with HPV were obtained; positive results regarding the HPV type (16 and/or 18) were found in 92.5% women and the presence of AFB1-DNA adducts were detected in 77.5% of the same positive HPV samples. Detection of AFB1-DNA adducts and genomic concentrations were correlated with the detection of two oncogenic types of HPV 16 and 18. AFB1-DNA positivity and higher genomic concentrations of AFB1-DNA adducts were correlated with an increased risk of oncogenic detection of HPV in cervical samples from women in Mexico. As a secondary objective, a hypothetical interaction of the adducts with the NRF2 pathway has been proposed, therefore activation of p62 and in turn E6 and E7 (HPV proteins) would inhibit the formation of autophagosomes, which would result in a presence or recurrence of CC.