bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Model Pembelajaran Terhadap Penguasaan Teknik Dasar Renang Gaya Dada
Authors: Wardiyanto Yayan
Published: February 2022

Berdasarkan hasil observasi di lapangan terdapat fakta bahwa dalam proses pembelajaran khususnya materi renang gaya dada, sebagian siswa terlihat kurang aktif, takut dengan air dan takut tidak bisa melakukannya sementara siswa yang lainnya bisa mengikuti pembelajaran, sehingga perlu ada solusi untuk menerapkan model pembelajaran yang dapat membangkitkan motivasi belajar sehingga tercapainya peningkatan penguasaan teknik dasar renang gaya dada. Tujuan penelitian adalah untuk mengetahui pengaruh model pembelajaran TGFU terhadap penguasaan teknik dasar renang gaya dada. Penelitian ini menggunakan metode eksperimen dengan bentuk One Group Pretest Posttest Design. Populasi 110 siswa kelas VIII A, B dan C SMP Sindangjawa Kabupaten Cirebon. Sampel 17 siswa putra dengan teknik pengambilan sampel random yang homogen. Hasil Penelitian pada Pretest diperoleh rata-rata untuk kelompok eksperimen yaitu 51,87, Posttest diperoleh rata-rata untuk kelompok eksperimen yaitu 37,28 dan hasil latihan diperoleh rata-rata 14,59. Teknik analisis data dengan menggunakan uji hipotesis melalui uji signifikansi dengan hasil bahwa t hitung lebih besar dari pada t tabel dimana t hitung > t tabel = 27,528 > 2,583. Hasil penelitian ini adalah model pembelajaran TGFU memberikan pengaruh yang signifikan terhadap penguasaan teknik dasar renang gaya dada.
Fenomena Aktivitas Fisik dan Olahraga dalam Perspektif Pasien Diabetes Melitus Tipe 2
Authors: Maulida Reyaan Irianti Bahana , Renaldi Fransiskus Samuel , Sauriasari Rani , Riyadina Woro
Published: February 2022

Diabetes melitus tipe 2 merupakan penyakit kronik dan membutuhkan tindakan khusus bagi pasien. Terapi untuk diabetes melitus tipe 2 dibedakan menjadi terapi farmakologi dan terapi non farmakologi. Contoh dari terapi non farmakologi untuk diabetes melitus tipe 2 adalah aktivitas fisik dan olahraga yang sesuai. Penelitian ini ditujukan untuk mengungkap berbagai aktivitas fisik dan olahraga yang dilakukan pasien untuk dapat membantu tenaga kesehatan dalam menyusun strategi edukasi yang sesuai. Penelitian ini merupakan studi kualitatif dengan menggunakan metode fenomenologi. Sebanyak 30 subjek terlibat dalam penelitian ini Pemilihan pasien dilakukan menggunakan metode sampling bola salju. Pengambilan data dari pasien dilakukan dengan metode wawancara mendalam (in-depth interviews). Wawancara mendalam dilakukan dengan menggunakan teknik probing untuk memvalidasi setiap pernyataan yang dikeluarkan oleh pasien.. Data diolah dengan metode transkrip dan dianalisis secara tematik untuk kemudian diinterpretasikan dalam bentuk pernyataan hasil wawancara. Dari penelitian ini, dapat disimpulkan bahwa sebagian besar pasien rutin melakukan aktivitas fisik dan olahraga. Beberapa pasien tidak dapat melakukan olahraga secara rutin akibat terhalang oleh waktu. Maka dari itu, diperlukan kolaborasi antara tenaga kesehatan untuk memberikan edukasi terkait aktivitas fisik dan olahraga yang sesuai bagi pasien Diabetes Melitus tipe 2.
Hubungan Aktivitas Fisik Terhadap Kebugaran Jasmani dan Prestasi Akademik Mahasiswa STKIP PGRI Sumenep
Authors: Supriyanto Nugroho Agung , Rasyid Ainur , Fepriyanto Andi , Helaprahara Dian
Published: February 2022

Penelitian ini mempunyai tujuan untuk melihat hubungan atau korelasi antara aktivitas fisik terhadap kebugaran jasmani dan prestasi akademik mahasiswa STKIP PGRI Sumenep. Subjek penelitian adalah 44 orang mahasiswa berjenis kelamin laki-laki dari program studi pendidikan jasmani kesehatan dan rekreasi angkatan tahun 2000. Pengukuran aktivitas fisik menggunakan kusioner IPAQ, pengukuran kebugaran jasmani menggunakan tes MFT dan pengukuran prestasi akadmik menggunakan indeks prestasi mahasiswa. Hasil penelitian menujukkan level aktivitas mahasiswa berada pada level sedang. Selain itu juga ditemukan ada hubungan antara aktivitas fisik terhadap kebugaran jasmani (p<0.05) dan tidak ada hubungan antara aktivitas fisik terhadap prestasi akademik mahasiswa (p>0.05). Hal ini menunjukkan bahwa aktivitas fisik mempunyai peran yang penting untuk meningkatkan level kebugaran seseorang dan untuk mencapai prestasi akademik dipengaruhi oleh berbagai faktor dari dalam ataupun dari luar
Georg Spalatin als Übersetzer
Authors: Nagel Kay
Published: February 2022

Based on individual studies (Hamm, Treu, Fasbender) and on fundamental works (Volz, Höß), the work illuminates the humanistic and legal translations, translation strategies and the necessary networking among people with an affinity for the Reformation in the early 16th century. It provides information on the persons mentioned and honoured with dedications, the contexts of the translations and the transcriptions of all prefaces from Spalatin’s pen. The work is the first comprehensive study of the translation work of the native Franconian, who made a career in Electoral Saxony as a prince educator, secretary and confidant of Martin Luther. As such, it lays the foundation for future research on the translator Georg Spalatin.
The ontogenetic pattern of Hippopotamus gorgops Dietrich, 1928 revealed by a juvenile cranium from the one-million-years-old paleoanthropological site of Buia (Eritrea)
Authors: MARTÍNEZ-NAVARRO Bienvenido , PANDOLFI Luca , MEDIN Tsegai , LIBSEKAL Yosief , GHINASSI Massimiliano , PAPINI Mauro , ROOK Lorenzo
Published: February 2022

An almost complete cranium of a juvenile individual from the late Early Pleistocene site of Buia, in the northern Afar (Danakil) Basin in Eritrea, reveals a different growth pattern of the extinct species Hippopotamus gorgops Dietrich, 1928 compared to the extant species Hippopotamus amphibius Linnaeus, 1758. The specimen shows important cranial features of Hip. gorgops (also visible in adult specimens), with a derived cranial anatomy that is related to the specialization to a more aquatic life style than other species of Hippopotamidae: elevated nuchal and sagittal crests, strongly elevated orbital cavities, short neurocranium and elongated palate. A geometric morphometrics analysis was performed in the lateral view on skulls of Hip. gorgops and Hip. amphibius, to investigate size-shape relationship and to compare ontogenetic growth trajectories between both taxa. The study revealed that, during growth (increase in size and age), variations in skull shape are prominent in Hip. amphibius; juvenile and adult individuals of Hip. gorgops display strong morphological similarities but size and shape are poorly correlated. The results support the hypothesis that in a relatively early ontogenetic stage, Hip. gorgops was more specialized in its aquatic adaptation than Hip. amphibius.
A Review of Mucinous Cystic and Intraductal Neoplasms of the Pancreatobiliary Tract
Authors: Ozcan Kerem , Klimstra David S.
Published: February 2022

Context.—

Although most pancreatic and bile duct neoplasms are solid, mucinous cystic neoplasms and intraductal neoplasms have been increasingly recognized even when clinically silent, thanks to the increased use of sensitive imaging techniques. Cystic and intraductal neoplasms of the pancreas are often resectable and curable and constitute about 5% of all pancreatic neoplasms. Owing to their preinvasive nature and different biology, recognition of these entities remains a major priority. Mucinous cystic neoplasms are histologically and clinically distinct from other cystic pancreatic neoplasms. Pancreatic intraductal neoplasms encompass 3 major entities: intraductal papillary mucinous neoplasm, intraductal oncocytic papillary neoplasm, and intraductal tubulopapillary neoplasm. Intraductal papillary neoplasms of bile ducts are also preinvasive mass-forming neoplasms with both similarities and differences with their pancreatic counterparts. All of these pancreatobiliary neoplasms have diverse and distinctive clinicopathologic, genetic, and prognostic variations.

Objective.—

To review the clinical, pathologic, and molecular features of mucinous cystic and intraductal neoplasms of the pancreatobiliary tract.

Data Sources.—

Literature review, diagnostic manuals, and guidelines.

Conclusions.—

This review will briefly describe well-known clinical and pathologic features and will focus on selected recently described aspects of morphology, grading, classification, and genomic alterations of cystic and intraductal neoplasms of the pancreatobiliary tract.
Spatial epidemiological analysis of Lyme disease in southern Ontario utilizing Google Trends searches
Authors: Kutera Maria , Berke Olaf , Sobkowich Kurtis
Published: February 2022

Lyme disease is of growing concern in Ontario with endemic areas increasing in size. Differential diagnosis of Lyme disease patients should include their exposure status assuming knowledge of high-risk areas. The goal of this study was a spatial analysis of Lyme disease in southern Ontario for the years 2015–2019 with a focus on the association between Lyme disease prevalence and Internet search frequencies recorded by Google Trends. A choropleth map visualized the raw prevalence of Lyme disease across the 28 public health units of southern Ontario. A disease cluster comprising five public health units was identified in eastern Ontario using the flexible scan statistic (standard morbidity ratio = 4.9, p = 0.01). Poisson regression modeling revealed an association between Lyme disease prevalence and the search term “Lyme disease” in Google Trends (p = 0.032). Lyme disease prevalence was correlated with Google Trend searches, with an increase in relative risk by a factor of 1.19 (CI95%: 1.03, 1.39) for every 1% increase in search activity. Knowledge of the existence and location of high-risk or exposure areas for Lyme disease is important to properly diagnose patients. Exploiting the association between Lyme disease and Internet search activity by the population at risk can also further disease surveillance.
Musculoskeletal disorders increases the insomnia severity in nurses
Authors: Cici Remziye , Yilmazel Gülay
Published: February 2022

Objectives To determine prevalence of musculoskeletal disorders and the relationship between insomnia severity among nurses working in a training and research hospital.

Material and Methods This descriptive study was carried out with 293 nurses. Cornell musculoskeletal disorders questionnaire for musculoskeletal disorders and insomnia severity index were used to determine the insomnia severity.

Results In our study, the severity of the discomfort was mostly moderate and mild in painful areas. There was a significant difference in terms of gender, educational status, marital status, seniority, types of working, and presence of chronic diseases for musculoskeletal disorders in different body regions (p<0.05). It was determined that the threshold level of insomnia was significantly higher in those with musculoskeletal disorders in other body regions except the knee and lower leg region (p<0.05).

Conclusion In our study, it was determined that musculoskeletal disorders were common in the upper body areas and the severity of insomnia was at the threshold level. Neck, right shoulder and right upper arm were risky body areas for insomnia.
Correlation of sleep quality and cardiac autonomic modulation in hemodialysis patients
Authors: Carneiro Erika Ribeiro , Azoubel Luana Anaisse , Dias Raimunda Carneiro , Dias Carlos José , Sá Emanuelle Sousa , Brito Dyego Araujo , Salgado Filho Natalino , Santos Elton Freitas , Rocco José Hermógenes , Mostarda Cristiano Teixeira , Bernardo Filho Mario
Published: February 2022

Objectives Sleep disorders in patients on hemodialysis are frequent, but few studies correlate these disorders with autonomic dysfunction in these patients. This study aimed to verify whether clinical and laboratory variables and heart rate variability are associated with worse sleep quality verified by the Pittsburg subjective scale in patients on hemodialysis.

Material and Methods A cross-sectional study was performed on forty-eight patients. Epidemiological, clinical, and laboratory data were collected. After were performed by recording the heart rate variability and applied Pittsburg questionnaires, Beck anxiety index (BAI), and Beck depression index (BDI). The global PSQI score >5 indicates that a person is a poor sleeper, the patients were divided according to the scores in the Pittsburg questionnaire into good and poor sleepers and the differences between all variables were analyzed.

Results Forty-eight patients were evaluated and the prevalence of 68.7% (n=33) of poor sleep quality was verified. From the depression and anxiety questionnaires, it was found that only 18.7% (n=9) had criteria for depression. In the analysis of the sympathetic dysfunction parameters, it was found that in the group with good sleep quality in the frequency domain (HFm2) and the LFnu in the group with worse sleep quality. There was a positive correlation between sleep quality scores the anxiety and depression scores. It is also verified that the variables LFnu had a positive correlation with higher scores of quality of sleep and HFnu had a negative correlation with the highest scores of quality of sleep.

Conclusion In patients undergoing hemodialysis, the poorest quality of sleep is correlated with worse cardiac autonomic modulation as well as higher scores on the depression and anxiety scales.
Smartphone applications for sleep tracking: rating and perceptions about behavioral change among users
Authors: Karasneh Reema A. , Al-Azzam Sayer I. , Alzoubi Karem H. , Hawamdeh Sahar , Jarab Anan S. , Nusair Mohammad B.
Published: February 2022

Introduction This study aims to assess existing sleep apps for mobile phones to determine the perceived effect of these applications on user’s attitudes, knowledge, willingness to change, and its likelihood to change behavior from a user’s perspective.

Material and Methods A systematic search was conducted through Google play store and iTunes Apple store using terms related to sleep tracking. Apps were evaluated using Mobile Application Rating Scale (MARS) tool for assessing and classifying mobile health applications quality. Additionally, a convenience sample of subjects were asked to evaluate the included apps for perceived sleep behavior changes.

Results The average MARS app quality score on a 5-point scale was 3.3. Between 30-50% of participants believed that sleep tracker apps are likely to increase awareness about sleep patterns and sleep hygiene, infuence sleep hygiene habits, and are likely to encourage help seeking for sleep hygiene when required.

Conclusion Apps available for sleep self-management and tracking may be valuable tools for self-management of sleep disorder and/or improving sleep quality, yet they require improvement in terms of quality and content, highlighting the need for further validity studies.
La monstruosidad y el signo: formas de la presignificación en el Renacimiento y la Reforma
Authors: Vega Ramos María José
Published: February 2022

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Criminal Law and Neuroscience: Theory and Practice in the Italian Perspective
Authors: Grandi Ciro
Published: February 2022

The debate on the impact on criminal justice of the empirical evidence offered by techniques of brain exploration and behavioral genetics shows no sign of diminishing, fed by literature now boundless and by case law in constant growth. In the Italian system, the impact of neuroscience at trial is still rather limited and substantially confined to its sedes naturalis, that is to say, the insanity defense. Even in this area, however, there is a very cautious, if not sometimes distrustful, attitude on the part of the courts, still doubtful about the epistemological reliability of neuroscientific evidence. The interdisciplinary dialogue is called upon to help overcome uncertainties and resistance, to avoid the underestimation of data endowed – albeit in a complementary and integrative function – with an increasingly objective value.

Summary: 1. Foreword. - 2. Neuroscience: an outline. - Neuroscience and criminal law in the light of the radical-revolutionary model. - 4. Neuroscience and criminal law in the light of the moderate-compatibilist model. - 5. An overview of the use of “neuroscientific evidence” in practice - 6. Neuroscience and the evaluation of criminal capacity: a first assessment. - 7. The (still) limited impact of neuroscience in the Italian criminal trial. Diagnosis and prognosis. – 8. Conclusions.
Léxico culinario en los «Elementos de higiene privada» (1846) de Pedro Felipe Monlau
Authors: Torres Martínez Marta
Published: February 2022

The present research deals with Elementos de higiene privada (1846), a treatise by Pedro Felipe Monlau about hygiene from the late 19th century. Our main objective is to study the culinary lexicon within this work, particularly the third section, dedicated to food science, where several intriguing chapters can be found, as the one titled “Preparation and Preservation of Food” (pp. 150-164). In accordance with Eberenz (2014: 30), apart from focusing on the culinary treatise, a historical lexicographer has to pay attention to a more varied textual typology. Particularly, we aim to organize the documented specialty terms in order to revise their presence, treatment and evolution in the Spanish lexicographic tradition.

En esta investigación nos aproximamos a un tratado sobre higiene publicado a finales del siglo XIX, Elementos de higiene privada (1846) de Pedro Felipe Monlau. Nuestro objetivo consiste en estudiar el léxico culinario incluido en esta obra, concretamente en la sección tercera, dedicada a la Bromatología, donde se encuentran capítulos tan sugerentes como el titulado “Preparación y conservación de los alimentos” (pp. 150-164). Siguiendo a Eberenz (2014: 30) consideramos que, además de centrar el interés en los tratados culinarios, un historiador del léxico ha de prestar atención a una tipología textual más variada. En particular, nos disponemos a organizar las voces de especialidad documentadas para después revisar su presencia, tratamiento y evolución en la tradición lexicográfica del español.
Venusins Autografer
Authors: Andersen Peter
Published: February 2022

Peter Andersen: Venusinus’s autographs

Today thirteen autograph manuscripts are known by the Danish humanist Jon JacobsenVenusinus (d. 1608), cited in older research particularly with reference to his oppositionto exorcism. His enemies compared him to Faust; an admirer described him as ‘theman with the enchanting name’. He first called himself Coronensis, alluding both tohis upbringing in Landskrona and to his close association with the royal house, but hechanged his name about 1595 to Venusinus, referring both to Ven, the island on whichhe claimed to have been born, and Venusia, Horace’s home town. Seven bookplatesprovide an insight into this Dane’s personal library. Among his books was a copy ofWilliam Lambarde’s Archaionomia, from which he quotes twenty-four Old English words.Five entries in his alba amicorum bear witness to his circle of friends, which includedseveral Calvinists. Three entries contain his hitherto neglected Latin and Greek mottos.The albums also allow partial reconstruction of his travels abroad. A recently rediscoveredletter to the German Calvinist Johannes Piscator is particularly interesting anddoubles the quantity of known text from Venusinus’s hand.
Deontic Autonomy in Family Interaction
Authors: Frick Maria , Palola Elina
Published: February 2022

The multimodal conversation analysis in this paper shows how an au pair and a mother use several turns consisting of various bodily and multilingual elements to persuade a 5-year-old to go to the bathroom. We examine the participants’ orientation to the child’s deontic autonomy; that is, his right to determine his own actions. The analysis shows that although the au pair and child disagree on whether the child should go to the bathroom, they both orient to the same norms of interaction and the norm of deontic autonomy more specifically.
Gestural Matching and Contingent Teaching
Authors: Majlesi Ali Reza
Published: February 2022

This study explores how iconic gestural matching in responsive turns is used in Swedish L2 talk not only to demonstrate understanding, but also as a referable by L1 speakers to highlight part of the previous turn as the focus of instruction. Gestural matching indicates intersubjective understanding (de Fornel, 1992), cohesion across turns (Koschmann & LeBaron, 2002), or conjoint actions (Lerner, 2002). In the context of L2 learning, they can be used for pedagogical purposes (Eskildsen & Wagner, 2015; Majlesi, 2015). This study reports on the use of gestural matching in “language cafés”, where gestures are recycled to make part of the prior turn salient and relevant for the emergence of learnables and for contingent teaching.
Land use and land cover dynamics and traditional agroforestry practices in Wonchi District, Ethiopia
Authors: Meragiaw Misganaw , Woldu Zerihun , Singh Bal Ram
Published: February 2022

Background

Investigating the land use and land cover (LULC) dynamics and the status of traditional agroforestry practices provide important data for policymakers. The main objective of this study was to assess the LULC dynamics and traditional agroforestry practices among smallholder farmers across the two agro-ecological zones in Wonchi District of Ethiopia.

Methods

Landsat images were acquired from Earth Explorer, and changes in LULC were quantified with three Landsat sensors in the three time-series (1985, 2001, and 2019). Supervised classification with maximum likelihood technique was employed using ERDAS Imagine and ArcGIS. A ground survey was conducted with 100 key informants who were selected from 10 sites using a purposive sampling method. The collected data were subjected to direct matrix ranking, use-value analysis of most important multipurpose plant species, and semi-structured interviews were conducted for qualitative analysis.

Results

In total, 103 agroforestry plant species belonging to 44 families were identified in Wonchi District, of which 74 were indigenous including seven endemic and 29 exotic species. The highest species (13) were recorded in the Fabaceae family. About 61% of species were reported in the midland agro-ecological zone. A mixed farming system was the most frequently (56%) reported source of income. The results of LULC changes from 1985 to 2019 showed that the agroforestry cover increased from 31.1% to 34.9% and settlement including road construction increased from 12.5% to 31.6% of the total area with an annual rate change of 0.3% and 2.7%, respectively. These changes corresponded with a decreasing trend of the forest, cropland, water body, and shrub at a rate of 4.7%, 1.3%, 0.8%, and 0.5%, respectively. The LULC changes were more pronounced in the highlands than in the midlands of Wonchi District. Expansion of settlement and tenure policy change are the main drivers for these changes in the area. The authors recommended that protecting and planting indigenous and multipurpose plant species is essential as restoration techniques for all degraded land-use types. Therefore, strengthening agroforestry practices and land-use planning is urgently needed for achieving multiple goals.
Comparative transcriptomes of three different skin sites for the Asiatic toad (Bufo gargarizans)
Authors: Lan Yue , He Lewei , Dong Xue , Tang Ruixiang , Li Wanyu , Wang Jiao , Wang Lei , Yue Bisong , Price Megan , Guo Tao , Fan Zhenxin
Published: February 2022

Toads release toxic dry secretions from glands in their skin. Toxin possesses a wide range of biological effects, but little is known about its specific gene expression pattern and regulatory mechanisms. The Asiatic toad (Bufo gargarizans) is widely used to produce toxin. Here, we explored the gene expression of 30 tissue samples from three different skin sites (parotoid gland, dorsal skin, and abdomen skin) ofB. gargarizans. Afterde novoassembly, 783,130 unigenes with an average length of 489 bp (N50 = 556 bp) were obtained. A total of 9,248 significant differentially expressed genes (DEGs) were detected. There were 8,819 DEGs between the parotoid gland and abdomen skin and 1,299 DEGs between the dorsal skin and abdomen skin, while only 1,283 DEGs were obtained between the parotoid gland and dorsal skin. Through enrichment analysis, it was found that the detected differential gene expressions corresponded to the different functions of different skin sites. Our key findings were the genetic expression of toxin secretion, the protection function of skin, and the related genes such asHSD3B,Cyp2c, andCAT,LGALS9. In conclusion, we provide useful transcript resources to study the gene expression and gene function ofB. gargarizansand other amphibians. The detected DEGs between different sites of the skin provided better insights into the genetic mechanisms of toxin secretion and the protection function of skin for amphibians.
Vibration Anomaly Detection Using Multivariate Time Series
Authors: Deac Crina , Călin Deac Gicu , Constantin Parpala Radu , Laurentiu Popa Cicerone , Popescu Constantin-Adrian
Published: February 2022

The paper presents a set of deep learning algorithms for detecting vibration anomalies in bearings using multivariate time series on datasets provided by Case Western Reserve University. The study considers a problem of multiclassification of the condition of the bearings depending on the type of defect, but also on the degree of defect, considering only punctual defects in an incipient phase. Once the data sets are correctly labeled and the algorithms are trained on this data, they can accurately predict the type and the size of defect. The model with the best results in the set is RNN - CNN (Recurrent Neural Network with Convolutions) giving an accuracy greater than 97% in all (load) cases.
Anticarcinogenic Efficacy of Fucoxanthin on HepG2 Cell Lines
Authors: Sangavi P , Langeswaran K , Kumar S Gowtham
Published: February 2022

Introduction: Hepatocellular Carcinoma (HCC) is considered one of the deadliest cancers which grow rapidly worldwide. Fucoxanthin can be acquired from edible brown seaweeds, reported that fucoxanthin has numerous physiological functions and biological abilities, and various medicinal properties. Aim: To evaluate the anti-carcinogenic efficiency of fucoxanthin against the Human Hepatoma Cell Line (HepG2). Materials and Methods: This in-vitro examination and research was carried from June 2018 to August 2018, at Alagappa University, Karaikudi, Tamil Nadu, India. Fucoxanthin at different concentrations was taken to demonstrate its antiproliferative potential and its cytotoxic effect. In this present examination, based on the outcome of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl2H-tetrazolium bromide (MTT) assay, 80 µM and 100µM were chosen for further in-vitro studies. It was noted that remarkable leakage of Lactate Dehydrogenase (LDH) and a noteworthy decrease in the Glutathione (GSH) content of 80µ M and 100µM of fucoxanthin treated HepG2 cells. Under light and fluorescence microscopic examination, there was a significant reduction in cell growth and cell proliferation in the fucoxanthin-treated HepG2 cells. Data were presented as the mean±standard deviation. The one-way analysis of variance (ANOVA) and Tukey’s multiple comparison method were used to find the level of significance. Results: The human HepG2 to be studied and analysed were divided into group I: control group; group II: comprising those cells treated with fucoxanthin in concentration of 80 µM; group III: comprising those cells treated with fucoxanthine in concentration of 100 µM. The results of the MTT assay put forward that fucoxanthin has the cytotoxic and anti-proliferative potential against HepG2 further fucoxanthin significantly alter the marker enzymes level (p-value <0.05). The therapeutic efficiency of fucoxanthin might be due to the antioxidant effect of the bioactive compound. In this present investigation, the results of in-vitro studies, fucoxanthin strongly put forward that it has potential anticarcinogenic efficacy against the hepatic tumour (p-value <0.05). Conclusion: The results of this analysis undoubtedly symbolise that fucoxanthin has anti-oxidant activity and anti-carcinogenic efficacy against primary liver cancer HCC. Due to their therapeutic efficacy, may be considered as an excellent candidate against HCC.
AVALIAÇÃO DOS CONSELHOS DE RECURSOS HÍDRICOS E COMITÊS DE BACIA HIDROGRÁFICA: UMA REVISÃO SISTEMÁTICA
Authors: Marcondes Felipe Silva , Moreira Simone Magela
Published: February 2022

A complexidade relacionada à gestão dos recursos hídricos requer a constante mensuração de sua governança, cujas análises precisam ser confrontadas para que seus resultados contribuam efetivamente para a qualidade das estratégicas, frente às escolhas das decisões. Assim, o objetivo desta revisão foi o de resumir o estado da arte relacionado aos procedimentos usados nas avaliações dos conselhos de recursos hídricos e dos comitês de bacias hidrográficas brasileiros. A busca foi iniciada por meio da seleção de artigos, dissertações e teses publicados nos bancos digitais do portal de periódicos da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e da Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). Divulgações nas duas últimas décadas (2000 a 2020) foram incluídas e classificadas quanto ao tema principal e à esfera de abordagem. Constatou-se que há disponibilizado apenas, 65 produções acadêmicas sendo 37 dissertações de mestrado (56,9%), 15 artigos (23,1%) e 13 teses de doutorado (20,0%). O número reduzido de avaliações destes órgãos colegiados, em particular dos conselhos, indica uma lacuna a ser investigada de modo que possam oferecer informações para a compreensão dos problemas despercebidos que prejudicam o funcionamento. Somente uma pequena parte (12%) das produções teve abrangência nacional, sendo a maioria (54%), casos locais, com limitado incremento na noção de impacto e promoção da melhoria contínua das políticas públicas. Destaca-se a necessidade de um maior fortalecimento institucional, com vista à melhoria da qualidade participativa, atuação responsável e o adequado apoio técnico, físico e financeiro, indigência comum na maioria dos estudos. Esta pesquisa contribui para a análise das evidências dos procedimentos, técnicas e métodos usados na avaliação destes órgãos colegiados, iniciando a sistematização das informações recuperadas de modo que um modelo de avaliação da qualidade possa ser construído.
LICENCIAMENTO AMBIENTAL NOS ESTADOS BRASILEIROS: OS PROCEDIMENTOS SERIAM OS MESMOS PARA UMA RODOVIA?
Authors: Santos Thereza Isabelle Silva dos , Vilas_Boas Thayla Francisca , Ferreira Patricia , Ribeiro Aline Carvalho , Almeida Maria Rita Raimundo e
Published: February 2022

Rodovias consistem em estruturas cuja importância é atribuída à capacidade de propiciar a circulação entre lugares de pessoas e carga. Empreendimentos desta tipologia impactam o ambiente de forma diferenciada de acordo com as características do projeto e do meio em que estão inseridos. Por isso, são consideradas atividades potencialmente causadoras de degradação ambiental, sendo assim, passíveis de Licenciamento Ambiental (LA) junto ao órgão ambiental competente. Frente à possibilidade legal de procedimentos diferenciados para cada estado, o artigo tem como objetivo comparar o processo de LA estadual de uma rodovia estadual hipotética com extensão de 50 km em sete estados brasileiros: Bahia, Espírito Santo, Minas Gerais, Paraná, Rio de Janeiro, Rio Grande do Sul e Tocantins. A metodologia aplicada envolveu análise documental e de conteúdo de legislações e da página eletrônica dos órgãos licenciadores estaduais, visando levantar e comparar informações e dados relacionados ao processo de LA. Levantou-se em cada estado o órgão ambiental, o conselho estadual de meio ambiente e a legislação norteadora do LA, assim como, anecessidade da Avaliação de Impacto Ambiental (AIA) e do Estudo de Impacto Ambiental (EIA) para a rodovia hipotética. Pode-se notar uma diferença na classificação do potencial poluidor e do porte da atividade nos diferentes estados, mas todos eles apontam para a necessidade de realização da AIA para a análise da viabilidade do empreendimento, porém, nem todos se atêm ao EIA como estudo ambiental, deixando possibilidade de estudos mais simplificados. Espera-se que as comparações e discussões realizadas neste artigo possam servir como orientação para o processo de melhoria do Licenciamento e Avaliação de Impacto Ambiental no Brasil.
AVALIAÇÃO DE CICLO DE VIDA DAS ROTAS TECNOLÓGICAS DE DISPOSIÇÃO DOS RESÍDUOS DE MADEIRAS GERADOS PELAS INDÚSTRIAS MOVELEIRAS DE PETRÓPOLIS, BRASIL
Authors: Simões Izabela , Van_Elk Ana Ghislane Henriques Pereira , Ferreira João
Published: February 2022

A cadeia de valor da madeira tem como fonte principal uma matéria-prima renovável, apesar disso ainda gera impactos ambientais decorrentes da fabricação dos produtos e do manejo inadequado dos resíduos. O aproveitamento da madeira pode chegar a menos de 50% ao longo do seu ciclo de vida. O objetivo deste trabalho consistiu em avaliar os impactos ambientais de diferentes destinações de resíduos de MDF (Medium Density Fiberboard) gerados em 11 indústrias do polo moveleiro de Petrópolis/RJ. Foram avaliadas três destinações praticadas pelas indústrias: aterro sanitário; queima; e envio para cama de aviários. Foi incluída, a rota alternativa de destinações para reciclagem para a produção de MDP (Medium Density Particleboard). A metodologia utilizada apoiou-se nas normas ISO 14040 e 14044 e a modelagem dos impactos de ciclo de vida utilizou o software SimaPro®. Foram avaliadas dez categorias de impactos ambientais associadas ao tratamento de 1 kg de resíduos de madeira. A destinação que apresentou menores impactos ambientais foi a de reciclagem. Para as alternativas praticadas pelas indústrias a destinação para queima apresentou a maior parte dos impactos evitados, enquanto o envio para aterro sanitário foi a opção com mais impactos ambientais. A escala de impactos ambientais identificados neste estudo vai em linha com a hierarquia de decisão apontada na Política Nacional de Resíduos Sólidos no Brasil e com os conceitos de economia circular, que visam priorizar a reciclagem em detrimento de opções de tratamento de “fim-de-tubo” como o aterro de resíduos.
Estado regulador e mercado educador: raízes burguesas da mercantilização da educação
Authors: De Melo Naara Queiroz , Rodrigues Melânia Mendonça
Published: February 2022

O presente artigo analisa o processo de mercantilização da educação no Brasil sob a ótica da relação Estado-mercado. Desse modo, contextualiza os princípios burgueses do Estado e sua primazia pela propriedade privada; discute a relação da educação com a ideologia do Estado Regulador e do Mercado Educador; e reflete sobre o fortalecimento do mercado, em detrimento do direito à educação. Para tanto, foi realizada uma pesquisa bibliográfica, fundamentada no materialismo histórico-dialético. Os resultados elucidam que a transformação da educação em mercadoria figura como a reprodução do contexto social no qual o sistema educacional está inserido, contribuindo para os propósitos do Estado.
Trabalho docente sob a lógica privatista empresarial [Amanda Moreira da Silva]
Authors: Vieira Nelma Bernardes
Published: February 2022

O presente texto é a resenha do livro Trabalho Docente sob a lógica privatista empresarial: a busca pela força de trabalho a serviço de um projeto hegemônico, escrito por Amanda Moreira da Silva, lançado em 2021, pela Editora CRV. O objetivo da autora é mostrar que está em curso no país uma precarização de novo tipo do trabalho docente. Uma precarização que amplia a expropriação do conhecimento dos docentes, desagrega a autonomia pedagógica, desqualifica o trabalho docente com o objetivo de moldá-lo aos interesses do capital e enfraquece os sindicatos para desmobilizar a luta coletiva. A autora utiliza o materialismo histórico-dialético para mostrar a totalidade do mundo do trabalho e chegar na particularidade do trabalho docente. O livro é dividido em três capítulos. "Quais opções se apresentam à educação e ao trabalho docente num país capitalista dependente em face das presentes tendências no mundo do trabalho?" Está é a questão que orienta a discussão presente no livro. Em um tom crítico, a autora aponta que as melhorias concretas para a classe trabalhadora só virão por meio da luta coletiva.
O Partido Comunista do Brasil e seus intelectuais na luta pela democratização da educação e cultura entre os anos 1945-1947
Authors: Loula Dourado Viana Marta
Published: February 2022

Este artigo traz uma sistematização acerca da educação popular impulsionada pelo Partido Comunista no processo de redemocratização política no Brasil em 1945, expondo a compreensão do Partido e de seus intelectuais sobre educação e cultura, a Campanha de alfabetização, e a experiência da Universidade do Povo, depois, Escola do Povo, que tinham como objetivos a elevação cultural e a instrução das massas populares e trabalhadoras. Trata-se de uma pesquisa bibliográfica e historiográfica com fontes documentais em jornais de esquerda e de ampla circulação no período em questão.
Da erradicação do analfabetismo nos territórios à territorialização da agroecologia: o que nos ensina a educação socialista cubana?
Authors: Pinheiro Barbosa Lia
Published: February 2022

As revoluções latino-americanas e caribenhas foram, em si mesmas, processos pedagógicos que conformaram um sujeito histórico-político popular e uma concepção de educação voltada para a consolidação de uma formação humana ancorada em um horizonte emancipatório. A Revolução Cubana é uma revolução em vigor, que nos legou lições a respeito de uma concepção de educação socialista. O artigo analisa esta concepção, partindo de quatro aspectos: os antecedentes pedagógicos da concepção de educação; os fundamentos educacionais, filosóficos e pedagógicos da revolução; a centralidade da alfabetização e da revolução agroecológica e, finalmente, os aprendizados resultantes deste processo que dura mais de seis décadas
Gestão dos recursos minerais no município de Canaã dos Carajás – PA na perspectiva dos cidadãos
Authors: De Almeida Poliana Bentes , Martins Simone , Barros Jones Nogueira , Coutinho Mauro Margalho
Published: February 2022

Apensar de ser alvo de muitas críticas, a mineração é considerada uma atividade fundamental para o desenvolvimento socioeconômico dos países, visto que os minerais são essenciais para a vida do homem contemporâneo. Neste artigo propõe-se a realização de um estudo de caso para compreender se a gestão de atividades mineradoras em duas comunidades localizadas no entorno da cidade de Canaã dos Carajás, no estado do Pará são realizadas conforme as normas que regulamentam este setor. A partir de dados coletados por meio de entrevistas, pesquisa documental e observação direta e sistematizados com a utilização da técnica de análise de conteúdo, foi constatada inexistência de diálogo entre a comunidade e a empresa mineradora e entre a comunidade e o Poder Público sobre a gestão dos recursos ambientais e financeiros. Conclui-se a necessidade de: tornar efetiva a gestão participativa; tonar os processos de tomada de decisões inclusivos, compreensíveis e transparentes para amenizar os impactos da atividade mineradora; melhorar os processos informacionais para com a sociedade para que ela possa auxiliar na proposição e acompanhamento de projetos que resultem em melhorias em sua qualidade de vida.
Produção de Conhecimento & Aprendizagem Socioprática em Cidades Amazônicas: uma análise da Gestão Social no Observatório Social de Belém
Authors: Guerra Júnia Fátima do Carmo , Vasconcellos Ana Maria , Teodósio Armindo dos Santos de Sousa
Published: February 2022

Este artigo tem como objetivo analisar a produção de conhecimento na Gestão Social construída no âmbito do Observatório Social de Belém (OSB). Para tanto, foram discutidas as premissas teóricas sobre Gestão Social apoiadas na ideia de cidades justas, demcráticas e sustentáveis, bem como a produção de conhecimento a partir da noção de aprendizagem socioprática, por considerar que este tipo de conhecimento permeia as práticas e as dinâmicas do Observatório Social de Belém. Os resultados derivados da pesquisa qualitativa demonstraram que a produção de conhecimento nessa iniciativa do campo da Gestão Social promovida pelas práticas e interações realizadas no OSB se dá em espaços de discussão, de diálogo e também de embates, os quais induzem a reflexão entre os atores envolvidos no contexto de cidades justas e sustentáveis. Porém, observou-se que, apesar da consistência das parcerias e interações firmadas com alguns grupos da sociedade civil e setores públicos há, por vezes, informações pouco disseminadas, o que torna o diálogo menos qualificado e traz grandes desafios para a produção de conhecimento compartilhada. Além disso, notou-se que há uma lacuna entre o setor empresarial e a sociedade civil mais vulnerável, de forma que esses segmentos pouco contribuem para a consolidação de cidades justas e sustentáveis.
Acesso à Justiça e Audiência Virtual no Contexto da Pandemia de Covid-19
Authors: Morais Káty Maria Nogueira , Rodrigues Diana Cruz , Vasconcellos Ana Maria de Albuquerque , Soares Junior Eden do Carmo
Published: February 2022

A temática do acesso à Justiça tem como uma de suas premissas a aproximação entre o Sistema de Justiça e a sociedade. No contexto da transformação digital, que foi intensificada em razão da crise sanitária da Covid-19, a discussão de como ocorre o acesso à Justiça em formatos digitais torna-se relevante, em especial em cenário periférico, incluindo cidades que pertencem à Amazônia Legal maranhense. O objetivo desta pesquisa é examinar as potencialidades e limitações ao acesso à Justiça de cidadãos por meio das audiências virtuais realizadas durante a pandemia da Covid-19 pelo Tribunal de Justiça do Estado do Maranhão (TJMA). Metodologicamente, a investigação é baseada em um estudo de caso qualitativo e exploratório, que tem como lócus o TJMA, através da observação não-participante das audiências virtuais e de análise documental. Os resultados coletados indicam que as sessões virtuais contribuíram para a continuidade da atividade jurisdicional, contudo foram observadas a necessidade de adaptações, conforme as condições de acesso de magistrados, advogados e partes. Dentre as potencialidades podem ser destacadas as reduções de custos e do excesso de formalismo em comparação com a audiência presencial e como limitações, indicam-se as desigualdades de estrutura de acesso à internet ou equipamentos, bem como a necessidade de adaptação que pode influenciar na interação dos participantes.  O estudo suscita temas para aprofundamento quanto às questões de exposição, publicização e assimetrias de condições técnicas e acompanhamento dos defensores no acesso às sessões por cidadãos.
Overexpression of Peroxiredoxin 3 in Cartilage Reduces the Severity of Age‐Related Osteoarthritis But Not Surgically Induced Osteoarthritis in Mice
Authors: Loeser Richard F. , Coryell Philip R. , Armstrong Alexandra R. , Collins John A. , Gopalakrishnan Priya , McDermott Katie A. , Ran Qitao , Carlson Cathy S.
Published: February 2022

Objective

The study objective was to determine whether overexpression of the mitochondrial antioxidant peroxidase, peroxiredoxin 3 (Prx3), reduces the severity of osteoarthritis (OA) in mice.

Methods

Age‐related OA (age 18 and 24 months) and OA induced by destabilization of the medial meniscus (DMM at age 6 months) were assessed in male mice that overexpress a human Prdx3 transgene encoding the Prx3 protein. Lox‐stop‐lox‐Prdx3 (iPrdx3) mice were crossed with aggrecan‐CreERT2 mice to produce iPrdx3AgCreERT2 or with Col2Cre to produce iPrdx3Col2Cre mice. Germline transgenics (Prdx3Tg) were also evaluated. Prx3 protein level was assessed by immunoblotting and functionally after induction of elevated mitochondrial hydrogen peroxide (H2O2) using menadione. Histological sections of stifle joints were scored for cartilage damage (Articular Cartilage Structure score [ACS]), osteophytes, and synovial hyperplasia and were evaluated by histomorphometry.

Results

Overexpression of Prx3 maintained mitochondrial membrane integrity and inhibited p38 phosphorylation in the presence of elevated H2O2. ACS scores of 18‐month‐old iPrdx3AgCreERT2 mice (mean ± SD, 4.88 ± 5.05) were significantly lower than age‐matched iPrdx3 controls (11.75 ± 6.34, P = 0.002) and trended lower in the 18‐month Prdx3Tg group (P = 0.14), whereas no significant differences between experimental and control groups at 24 months of age or in OA induced by DMM surgery were noted. Osteophyte scores trended lower in the 18‐month‐old Prdx3Tg group (P = 0.09) and at 24 months in the iPrdx3Col2Cre mice (P = 0.05). There were no significant group differences in synovial hyperplasia or histomorphometric measures.

Conclusion

Overexpression of the mitochondrial peroxidase Prx3 reduced the severity of age‐related OA, but not at advanced ages and not in DMM‐induced OA in younger mice.
A High‐Fidelity Skin‐Attachable Acoustic Sensor for Realizing Auditory Electronic Skin
Authors: Lee Siyoung , Kim Junsoo , Roh Hajung , Kim Woongji , Chung Sein , Moon Wonkyu , Cho Kilwon
Published: February 2022

Wearable auditory sensors are critical in user‐friendly sound‐recognition systems for smart human–machine interaction and the Internet of Things. However, previously reported wearable sensors have limited sound‐sensing quality as a consequence of a poor frequency response and a narrow acoustic‐pressure range. Here, a skin‐attachable acoustic sensor is presented that has higher sensing accuracy in wider auditory field than human ears, with flat frequency response (15–10 000 Hz) and a good range of linearity (29–134 dBSPL) as well as high conformality to flexible surfaces and human skin. This high sound‐sensing quality is achieved by exploiting the low residual stress and high processability of polymer materials in a diaphragm structure designed using acousto‐mechano‐electric modeling. Thus, this acoustic sensor shows high acoustic fidelity by sensing human‐audible sounds, even loud sounds and low‐frequency sounds that human ears cannot detect without distorting them. The polymer‐based ultrasmall (<9 mm2) and thin sensor maintains sound‐detection quality on flexible substrates and in a wide temperature range (25 to 90 °C). The acoustic sensor shows a significant potential of auditory electronic skin, by recognizing voice successfully when the sensor attached on human skin is connected to a commercial mobile device running the latest artificial intelligence assistant.
Band‐Like Charge Transport in Small‐Molecule Thin Film toward High‐Performance Organic Phototransistors at Low Temperature
Authors: Ji Deyang , Jiang Ting , Zheng Yingshuang , Sun Yajing , Wei Zhongming , Li Liqiang , Hu Wenping
Published: February 2022

Organic phototransistors (OPTs) are playing an indispensable role in organic optoelectronics, which greatly show their promising application in optical communication, video imaging, missile guidance, and night vision. However, because the thermally activated mode dominated for thin‐film devices leads to a sharp drop in mobility at low temperatures, until now, most of the studies about OPTs are performed at room temperature, severely hindering their further potential optoelectronic application over a broad range of temperatures, especially at low temperature environment. In this work, the optoelectronic properties of a small molecule (2,6‐diphenylanthracene, DPA) based OPTs with band‐like transport are studied at low temperatures. The devices exhibit outstanding optoelectronic properties in terms of mobility (2.6 cm2 V−1 s−1), on/off ratio (≈104), detectivity (1013 Jones), and external quantum efficiency (2500%) even at 150 K, which is superior to the performance of devices with thermally activated mode. In addition, the organic photodetector at low temperatures is also fabricated. Our results demonstrate that organic π‐conjugated DPA small‐molecule has great potential in low‐temperature application.