bluuebunny/crossref_metadata_2025 huggingface dataset:
Kedudukan Keluarga dalam Mempengaruhi Kepatuhan Ibu Hamil Mengkonsumsi Tablet Fe
Authors: Arjita I Putu Dedy , Fihiruddin Fihiruddin , Hanafi Fachrudi
Published: February 2022

Anemia gizi besi merupakan salah satu masalah gizi utama di Indonesia, yang prevalensi pada ibu hamil masih tinggi yang berkisar antara 50-70%. Angka kejadian anemia gizi besi pada ibu hamil di Indonesia adalah 51%. Keberhasilan pemenuhan zat besi pada ibu hamil dapat terjadi apabila ibu hamil patuh mengkonsumsi tablet Fe sesuai dengan aturan yang diberikan. Penelitian ini bertujuan untuk mengetahui kedudukan keluarga dalam mempengaruhi kepatuhan ibu hamil mengkonsumsi tablet Fe. Jenis penelitian ini adalah observational analitik dengan disain penelitian Cross Sectional. sampel dalam penelitian ini semua ibu hamil trimester I dan II yang berada di lokasi penelitian dan memenuhi kriteria tertentu. Jumlah sampel diambil berdasarkan jumlah ibu hamil trimester I & II sampai bulan januari tahun 2020. Hasil penelitian menunjukkan jumlah kehamilan privigravida dan multigravida adalah 33.3% dan 66.7%. Persentase yang memberi saran dalam minum Fe adalah bidan (90.4%) dan dokter (9.6%). Peran keluarga terdekat dalam memberi saran minum tablet Fe yaitu suami (88,5) dan orang tua (11,5). Berdasarkan hasil analisis uji chi-square pada tabel di atas didapatkan nilai p-value 0,000 yang berarti terdapat hubungan antara orang yang menyarankan dengan rutinitas minum tablet Fe pada ibu hamil.  Peranan suami sangat besar terhadap konsumsi tablet Fe pada ibu hamil
Kejadian Stunting terhadap Perkembangan Anak Usia 24 – 59 Bulan
Authors: Utami Wardianti Putri , Najahah Imtihanatun , Sulianti Aty , Faiqah Syajaratuddur
Published: February 2022

Stunting merupakan bentuk kegagalan pertumbuhan (growth faltering) akibat akumulasi ketidakcukupan nutrisi yang berlangsung lama mulai dari kehamilan sampai usia 24 bulan. Stunting menjadi permasalahan karena berhubungan dengan meningkatnya risiko terjadinya kesakitan dan kematian, perkembangan otak suboptimal sehingga perkembangan motorik terlambat dan terhambatnya pertumbuhan mental. Penelitian ini bertujuan untuk mengetahui hubungan antara kejadian stunting dan tidak stunting dengan perkembangan anak usia 24 – 59 bulan di Desa Lembar Selatan. Metode yang digunakan adalah observasional analitik dengan pendekatan cross sectional. Partisipan dalam penelitian ini adalah semua balita yang berusia 24 – 59 bulan sebanyak 440 balita. Pengambilan sampel menggunakan teknik proportional sampling dengan jumlah sampel dibagi menjadi dua yaitu sampel kasus sebesar 33 sampel dan sampel kontrol sebesar 33 sampel, sehingga total sampel sebesar 66 sampel. Analisis bivariat yang dilakukan menggunakan uji chi square. Hasil penelitian menunjukkan sebagian besar balita stunting memiliki perkembangan dicurigai/suspect adanya keterlambatan (60,6%) dan balita tidak stunting memiliki perkembangan normal (87,9%). Hasil analisis menggunakan uji chi square diperoleh nilai signifikan yaitu 0,000 lebih kecil dari α (0,05). Sehingga, dapat disimpulkan terdapat hubungan antara kejadian stunting dan tidak stunting dengan perkembangan anak usia 24 – 59 bulan di Desa Lembar Selatan.
Factors Affecting Smoker Visits In Upaya Berhenti Merokok Clinics
Authors: Marsanti Avicena Sakufa , Ayu Woro Dyah , Ratnawati Riska
Published: February 2022

Upaya Berhenti Merokok Clinic is one of program from public health center which given from government. This clinic contains the smoke-free area and to help smokers who want to quit smoking. The objectives of this analyzing factor that influence the smoker visits in Upaya Berhenti Merokok clinics.In this research, the researcher uses descriptive quantitative research as approach. The method of research is analytical survey while the type of research is cross sectional. Total population of 187 people and using a sample of 126 people.The result of chi-square test shows that was a significant correlation between independet variable was knowledge (p-value = 0,003), intention (p-value = 0,001), attitude (p-value = 0,002), self-motivation (p-value = 0,010), and family support (p-value = 0,014) on smoker visits. And the results of the regressi logistic test most influential variables which are knowledge (p-value = 0.061), attitude (p-value of 0.060), self-motivation (p-value = 0,0153).The most influential variable was attitude with a result of 3,713 meaning that the attitude variable which are the most influential on smokers visit. From this study, the researcher concluded  that the great effect on active smoker who visited on Upaya Berhenti Merokok clinics at Tawangrejo primary health center was attitude.
REVIEW LITERATUR PENGARUH PEMBERIAN AROMATERAPI LEMON TERHADAP EMESIS GRAVIDARUM
Authors: Wulandari Rr Catur Leni , Sulistyowati Rini
Published: February 2022

Pendahuluan : Mual muntah (Emesis Gravidarum) sering terjadi pada ibu hamil trimester 1. Penyebabnya karena peningkatan hormon estrogen dan HCG pada awal kehamilan. Salah satu dampaknya yaitu Dehidrasi yang mengakibatkan janin mengalami masalah  maka dari itu diperlukan terapi. salah satu terapi untuk menangani yaitu dengan aroma terapi lemon. Metode : Literatur mancanegara ditelusuri melalui sarana elektronik dengan penuntun kata kunci (emesis, terapi lemon, aromaterapi). Artikel seleksi berjumlah 8 tentang pengaruh aromaterapi lemon terhadap emesis gravidarum Hasil : adanya perbedaan emesis gravidarum pada pemberian aromaterapi dengan perlakuan yang sama. Pembahasan : salah satu penanganan untuk emesis gravidarum yaitu dengan cara nonfarmakologis yaitu dengan pemberian aromaterapi lemon. Aroma terapi lemon mengandung limonene 66-80%, geranil asetat, nerol, linalil asetat, pinene 0,4– 15%, pinene 1-4%, terpinene 6-14% dan myrcen. Senyawa kimia seperti geranil asetat, nerol yang bermanfaat untuk antidepresi, nantiseptik, antispasmodik meredakan perasaan cemas, stres, dan lelah. Kesimpulan : pemakaian aromaterapi lemon efektif untuk mengurangi terjadinya emesis gravidarum
STUDY LITERATUR PENGARUH SENAM PEROUDIK (PEREGANGAN OTOT PERUT DAN KOMPRES DINGIN) TERHADAP PENURUNAN NYERI HAID PADA REMAJA PUTRI
Authors: Rahayu Endah , Sundayani Lina
Published: February 2022

Latar Belakang : Dismenore atau nyeri haid merupakan keluhan ginekologi yang umum dialami perempuan. Nyeri haid ini merupakan suatu gejala dan bukan suatu penyakit. Hampir semua wanita mengalami rasa tidak enak pada perut bagian bawah saat menstruasi. Uterus atau rahim terdiri atas otot yang juga berkontraksi dan relaksasi.Tujuan : Untuk mengetahui pengaruh Senam peregangan otot perut dan kompres dingin Terhadap Penurunan Nyeri Haid Pada Remaja Putri.Metode : Menggunakan studi literatur berdasarkan refrensi yang relevan dari judul terkait kemudian di analisis secara mendalam untuk menghasilkan sebuah kajian komperhensif mengenai objek penelitian. Peneliti melakukan pencarian journal melalui dengan menggunakan kata kunci dan berbasis journal, melalui Gogle Scholar,Garba Rujukan Digital (GARUDA Ristekdikti) dan Google Search. Literatur yang di gunakan adalah yang di publikasikan dari tahun 2015 sampai dengan 2020.Hasil : Berdasarkan hasil 20 jurnal yang telah direview dan didapatkan hasil dari 8 jurnal yaitu sebagian besar karakteristik Responden usia menarche yaitu  12-18 tahun dan rata-rata nyeri yang di rasakan  dari hasil review ke 8 jurnal sebagian besar intensitas nyeri berada pada nyeri sedang. Peregangan otot perut dan kompres dingin terdapat pengaruh dalam penurunan nyeri haid pada remaja.  Kesimpulan: Dari hasil literatur review ini dapat ditarik kesimpulan  bahwa untuk usia haid pertama kali berada pada rentang usia 12-18 dan nyeri yang dirasakan pada saat menstruasi nyeri  sedang serta peregangan otot perut dan kompres dingin mampu menurunkan nyeri haid.
PENGARUH PENDAMPINGAN KELUARGA TERHADAP TINGKAT KECEMASAN IBU PRIMIPARA DI WILAYAH KOTA MATARAM
Authors: Solehah Rizki Oktaviani , Hanafi Fachrudi
Published: February 2022

Latar Belakang :. Gangguan kecemasan sering dialami terutama oleh ibu primipara yang muncul akibat ketidakmampuan dan belum siapnya ibu untuk menerima kehadiran bayinya yang membutuhkan perawatan khusus pada minggu pertama kelahirannya.Keberadaan pendamping akan membawa dampak yang baik karena dapat memberikan dukungan, semangat, dan rasa aman bagi ibu.Tujuan : Untuk mengetahui adanya pengaruh pendampingan keluarga terhadap tingkat kecemasan ibu nifas primipara di Wilayah Kota Mataram.Metode : Penelitian ini menggunakan rancangan Quasi Eksperimen dengan pendekatan Pretest and Posttest Control Design, pengambilan sampel dengan teknik accidental sampling diperoleh 34 ibu nifas post SC yang telah disesuaikan dengan kriteria inklusi dan eksklusi. Instrument dalam penelitian ini adalah kuisioner.Hasil : Rata-rata tingkat kecemasan ibu nifas sebelum diberikan perlakuan pada kelompok intervensi adalah 48,24namun setelah diberikan intervensi rata-rata tingkat kecemasan ibu nifas adalah 27,65, sehingga terjadi penurunan skor rata-rata kecemasan. Sedangkan pada kelompok control, rata-rata tingkat kecemasan sebelum perlakuan adalah adalah 49,29namun setelah diberikan perlakuan rata-rata tingkat kecemasan ibu nifas turun menjadi 29,53. Uji ststistik denganIndependent T test nilai signifikansi (p) sebesar 0,107>0,05.Kesimpulan : pendampingan keluarga tidak berpengaruh dalam menurunkan tingkat kecemasan ibu nifas primipara di wilayah kota Mataram.
PENGARUH KOMBINASI SENAM KEGEL DAN RELAKSASI NAFAS DALAM TERHADAP NYERI LUKA PERINEUM PADA IBU NIFAS
Authors: Amarina Arnita Rizka , Irmayani Irmayani , Sudarmi Sudarmi
Published: February 2022

Latar Belakang : ibu nifas akan mengalami berbagai gangguan dan yang terbanyak adalah gangguan nyeri yang mencapai 70,9%. Penyebab utama nyeri tersebut adalah jahitan perineum dari fenomena yang terjadi untuk mengurangi nyeri ibu bisa melakukan relaksasi nafas dalam dan senam kegel.Tujuan : untuk mengetahui pengaruh kombinasi senam kegel dan relaksasi nafas dalam terhadap nyeri luka perineum pada ibu nifas di UPT BLUD Puskesmas Meninting Metode : penelitian ini menggunakan rancangan penelitian Quasi experiment dengan jenis Pre and Post Test With Control Group Design. Populasi adalah seluruh ibu nifas, sample diambil dengan Purposive Sampling dengan jumlah sampel 30 responden. Analisa data menggunakan analisis univariat dan bivariat menggunakan Kruskal WallisHasil : Nyeri perineum pada ibu nifas sebelum dan sesudah dilakukan senam kegel memiliki rata-rata selisih yaitu 3,60 dan mean rank 11,45. Relaksasi nafas dalam memiliki rata-rata selisih yaitu 3,50 dan mean rank 11,35. Kombinasi senam kegel dan relaksasi nafas dalam memiliki rata-rata selisih yaitu 5,50 dan mean rank 23,70. Uji statistik menggunakan Kruskal wallis hasil didapatkan ada pengaruh senam kegel dan relaksasi nafas dalam dengan p-value 0,001 < α 0,05.Kesimpulan : Ada pengaruh kombinasi senam kegel dan relaksasi nafasdalam terhadap nyeri luka perineum pada ibu nifas        Abstract Background: post partum mothers will experience various disorders and the most is pain disorders that reach 70.9%. The main cause of the pain is the perineal suture from the phenomenon that occurs to reduce the pain of the mother can do deep breath relaxation and kegel exercise. Aim : To determine the effect of combination kegel exercise and deep breath relaxation on perineal wound pain in postpartum mothers in UPT BLUD Meninting Health Center. Methods : this study used Quasi Experimental research design with the type of Pre and Post Test With Control Group Design. The population of this research that all childbirth mother, samples were taken by purposive sampling with a sample of 30 respondents. Analysis of the data using univariate and bivariate analyses using Kruskall Wallis. Results : Perineal pain in post partum women before and after Kegel exercises has an average difference of 3.60 and mean rank 11.45. Deep breath relaxation has an average difference of 3.50 and mean rank 11.35. The combination of Kegel exercises and deep breathing relaxation has an average difference of 5.50 and mean rank 23.70. The statistical test using Kruskal wallis results showed there was the effect combination of  kegel exercise and deep breath relaxation with p-value 0.001 <α 0.05. Conclusion: There is an effect of the combination of kegel exercise and deep breathing relaxation on perineal wound pain on postpartum mothers
PENGARUH SENAM HAMIL TERHADAP KECEMASAN DAN KUALITAS TIDUR IBU HAMIL TRIMESTER II DAN III
Authors: Yunitasari Ika , Suwanti Suwanti , Halimatusyaadiah Siti
Published: February 2022

Wanita hamil dianjurkan melakukan olahraga ringan selama hamil agar ibu dan janin lebih sehat dan berkurangnya masalah-masalah yang timbul pada kehamilannya. Salah satu olahraga ringan yang dapat dilakukan ibu hamil ialah senam hamil. Gerakan senam hamil terkandung efek relaksasi yang bermanfaat menstabilisai kecemasan dan mengurangi rasa takut dengan cara relaksasi fisik dan mental, serta mendapatkan informasi yang mempersiapkan mereka untuk mengalami apa yang akan terjadi selama persalinan dan kelahiran. Tujuan penelitian untuk mengetahui apa saja yang mempengaruhi kecemasan dan kualitas tidur ibu hamil trimester 3 dalam menghadapi persalinan. Desain penelitian yang akan digunakan adalah Quasi Experimen dengan pendekatan One Group Pretest Posttest Design yaitu rancangan yang tidak ada kelompok pembanding, tetapi paling tidak sudah dilakukan observasi pertama (prestest) yang memungkinkan menguji perubahan-perubahan yang terjadi setelah adanya Experiment. Hasil penelitian rata-rata skor tingkat kepercayaan diri ibu hamil sebelum diberikan sebesar 65,66 dengan standard deviasi 4,73, skorterendah 56 danskortertinggi 77. Dan rata-rata skor tingkat kualitas tidur sebesar 70,80 dengan standard deviasi 3,06, skor terendah 64 dan skor tertinggi 78. Kesimpulan: Ada pengaruh senam hamil terhadap kecemasan dan kualitas tidur ibu hamil trimester II dan  III. AbstractPregnant women are encouraged to exercise lightly during pregnancy so that the mother and fetus are healthier and reduce the problems that arise in pregnancy. One of the light exercise that can be done by pregnant women is pregnancy exercise. In fact the pregnancy exercise contains relaxation effects that are useful to stabilize anxiety and reduce fear bymeans of physical and mental relaxation, and get information that prepares them to experience what will happen during labor and birth.To find out what affects the anxiety and sleep quality of third trimester pregnant women in the face of labor. The research design that will be used is Quasi Experiment with the One Group Pretest Posttest Design approach that is a design that has no comparison group, but at least the first (prestest) observation has been carried out which allows testing of changes that occur after the Experiment. Results: The average score of the confidence level of pregnant women before being given was 65.66 with a standard deviation of 4.73, the lowest score of 56 and the highest score of 77. And the average score of sleep quality was 70.80 with a standard deviation of 3.06 , lowest score 64 and highest score 78. Conclusion: There is an Effect of Pregnancy Gymnastics on Anxiety and Sleep Quality of Trimester II and III Pregnant Women.
Selling Wellness: An Analysis Of Goop And Poosh’s Visual Marketing On Instagram
Authors: Rastrick Hannah
Published: February 2022

In conjunction with the rising “self-care” culture, wellness has become a key consumer trend in Western societies. The multi-trillion-dollar industry can, perhaps, thank social media for its significant growth in recent years. With proven benefits pertaining to brand awareness, consumer engagement, and purchase intention, social media has become an integral element of the twenty-first century business, particularly within the wellness industry. However, social media scholars have yet to sufficiently address the corporate approach to selling wellness. Engaging with everything from mindfulness and nutrition to fitness and beauty, how do wellness companies market themselves in such a multidimensional industry?

This Major Research Paper explores the Instagram marketing strategies of two globally
renowned wellness companies, goop and Poosh. A qualitative content analysis, guided by a
visual social semiotic framework, was conducted on 100 of the companies’ most-liked image-based posts from January to May 2021. The findings of this study suggest that goop and Poosh’s
content generates more likes on Instagram when it prioritizes the physical wellness domain,
emphasizes celebrity affiliation, utilizes high modality, people-centric imagery, incorporates an
aesthetic of concealment/fragmentation, and references a “link in bio.”
Twitter as the Teacher: What the Digital Afterlives of Hollywood’s Sports Films Tell Us That the Motion Pictures Don’t
Authors: Tahir Tasala
Published: February 2022

The murder of George Floyd in 2020 drew new attention to the discourse surrounding
representation in North America. Western sports leagues have been at the forefront of race
conversations during this time, but the dialogue extends to popular sports films as well. Through
a critical discourse analysis, this MRP argues that there are several insights to be learned from
the digital afterlives of three sports films. This study first outlines examples of how the White
saviour trope is enacted in Glory Road (2006) and The Blind Side (2009), and how the
academically poor performing Black student-athlete trope is performed in Coach Carter (2005).
Next, it explores the digital afterlives of these films today, specifically on Twitter. The findings
suggest that each film occupies a significant space in the lives of its viewers. The digital
afterlives provide insights into the importance of education in the athlete-student relationship,
racism of the past and how much has or has not changed, the formation of the family unit, and
the issues that arise from using films as a teaching tool for Black pain. The digital afterlives of
these films create space for a discussion about these insights, which is significant during a time
of cancel culture as this culture contributes to the demise of critical thinking with its emphasis on
turning the cheek to something that does not agree with one’s ideologies rather than responsibly
and cognitively interacting with contrary views. To help stop this close-minded cycle and foster
an understanding for how to critically examine films and other media texts, a media literacy
assignment for middle school students accompanies this MRP.

 Keywords: Black, athletes, sports films, tropes, stereotypes, representation, race, digital afterlife,
Twitter, media literacy, Coach Carter, Glory Road, The Blind Side
Trends, Issues, and Challenges on Early Childhood Programs: Shaping Sustainable Future for Children
Authors: Nanquil Luisito M. , Sawalmeh Murad Hassan , Domingo Ardee Glenn , Tanjente Mark Paolo Y.
Published: February 2022

This study examined different materials and articles that are connected with the experiences, observations, and insights of the researchers. They analyzed the current challenges and changes in the implementation of early childhood programs that affect the lives and learning of children. Through critical analysis of the materials and introspection of their own reflections and insights, the researchers were able to come up with conclusions and insights that could help educators, administrators, social workers, and volunteers to have a clear picture of the situations, contexts, and challenges being faced by those who have direct engagement with children. Moreover, trends, issues, and problems were also discussed so that researchers of this paper could offer sound and sustainable proposals that could identify the needs and diversities of children and the programs suitable to the existing needs and diversities.
Written Report and Correspondence Errors of Technical Assistance (TA) Providers
Authors: Bargo Darwin D.
Published: February 2022

Writing reports and correspondence are just some of the tasks that technical assistance (TA) providers do as they accomplish their day-to-day duties and functions. This study investigates errors found in the documents written by the TA providers including coordinators, master teachers, head teachers, school heads, district supervisors, and division supervisors considering Error Analysis (EA) Model by Carl James (1998). The data were taken from 94 soft copies of purposively collected and classified documents according to types. Results revealed that the topmost written documents based on percentages as used in this study are memorandum, narrative reports, and letters although there are still others in accordance with their mandates and job descriptions specifically on their respective Key Results Areas (KRAs). There were errors identified in the written reports and correspondence of the TA providers in the sentence level which revolve on (1) grammar – which highlighted points pertaining to preposition, article, agreement, verb, pronoun, noun, redundancy, determiner, quantifier, sentences, and adjective, (2) punctuation – mainly revolved on comma, hyphen, colon, and other punctuations, (3) capitalization – that falls on changing or checking, and congruency on the capitalization of words, and (4) spelling – words from the sentences were marked check, change, and correct spellings. There were also errors in the paragraph level under (1) development – which errors generally include inconsistencies of the expected patterns, formats which were not in accordance with relevant issuances, reports were merely collected from the concerned persons, thoughts within the reports need to be polished for clarity, reports also need to be rechecked considering the flow and organization of ideas, and mechanical aspects, (2) coherence – connection of thoughts from the paragraph before and after paragraphs, and use of transitional markers (TM) to connect ideas, (3) unity – word/s change, join or merge, replace, and separate which is sometimes a result of typo errors, and (4) point of view - written in lower positions' point of view, and improper use of 1st, 2nd and 3rd persons. The writing skills enhancement program and activities offered to the TA providers, the conclusions and recommendations on the basis of the results are presented in the full paper.
Dealing with the Learners’ Language Anxiety: A Pedagogical Inquiry
Authors: REYES CHRISTIAN LAWRENCE N.
Published: February 2022

This paper ought to revisit the place of language anxiety of learners in the context of second language acquisition. Specifically, the researcher dealt with its four components: communicative apprehension, fear of negative evaluation, test anxiety, and anxiety in the English classroom. These components have greatly impacted language learning based on the recent research conducted. Also, this paper untangled various findings coming from language experts to support the finding of the study. It is also worth noting that this paper would end with implications of the results generated from the responses of participants. They used a standardized research instrument adapted from Foreign Language Classroom Anxiety Scale (FLCAS) originally developed by Horwitz, Horwitz, and Cope (1986). The researcher used Statistical Packages for Social Sciences (SPSS) to treat the data. The findings were presented using the necessary tables and figures. It ended up with general implications and recommendations on how stakeholders could lessen the learners' high level of anxiety in a second language classroom.
RANCANG BANGUN PROTOTIPE PENGAMAN KENDARAAN BERBASIS GPS KOMUNIKASI PESAN TELEGRAM DAN THINGSPEAK
Authors: Fatoni Mukhammad , Adiananda
Published: February 2022

Kasus pencurian kendaraan terjadi karena berbagai faktor, yaitu: sistem keamanan kendaraan yang minim, kurangnya pengawasan dan lokasi mudah untuk melakukan pencurian. Pencurian kendaraan bermotor, sering terjadi pemilik kendaraan kesulitan dalam tracking kendaraan yang dibawa oleh pencuri. Pembuatan sistem pengaman kendaraan bertujuan sebagai pengaman kendaraan pada saat parkir dan monitoring koordinat kendaraan secara real time yang terintegrasi web server thingspeak dan pesan telegram sebagai kontrol sistem. Rancang bangun alat diawali mencari referensi tinjauan pustaka, mendesain sistem, yang meliputi perancangan hardware dan perancangan software, selanjutnya sistem akan diuji. Pengujian dan analisa meliputi pengujian respon alat terhadap pesan telegram, pengujian lock sinyal GPS, pengujian akurasi pembacaan data GPS, pengujian sensor getar SW-420 pada sistem dan pengujian sistem secara keseluruhan. Hasil pengujian respon alat terhadap pesan telegram dengan rata-rata waktu 19.8 second. Hasil pengujian lock sinyal GPS dengan rata-rata waktu 266.67 second. Hasil pengujian akurasi pembacaan data GPS dengan rata-rata selisih jarak 19.99 meter. Hasil pengujian sensor getar SW-420 Pada sistem, jika kondisi sensor mendeteksi getaran maka output sensor High sehingga buzzer aktif dan notifikasi pesan telegram masuk ke akun telegram pengguna. Pengujian sistem secara keseluruhan meliputi pengujian mode kontrol sistem dan pengujian mode informasi sistem
Assessment of Seismic Load Capacity of a Slender Masonry Clock Tower
Authors: Sözen Şahin
Published: February 2022

The paper presents the seismic vulnerability assessment of a historical masonry clock tower by means of the finite element method. The mechanical behavior and failure mechanism of these structures must be well understood in order to evaluate their performance and select an appropriate retrofit approach when needed. Stone towers, which sometimes have complex geometries and irregularities and are often designed for vertical loads, are vulnerable to lateral loads, especially earthquake loads, due to the slenderness of the tower and the limited ductility of the stone. This study aims to determine the horizontal load capacity of a magnificent clock tower by investigating its structural behavior using the finite element method. The analyzes carried out considering the seismicity of the region showed that the clock tower would be severely damaged or completely collapsed in case of an earthquake with an exceedance probability of 10% in 50 years. In non-linear time history analyses, the maximum base shear force to weight ratio was calculated as 0.27. The maximum drift ratio at the top of the clock tower reveals that the tower exceeds the collapse prevention performance level. The residual displacements obtained from non-linear time history analysis prove that plastic deformations occur on the tower body. In the light of this data, it is considered that the clock tower needs to be retrofitted with acceptable restoration procedures against possible earthquakes in the region.
Stuðningsmeðferð í tannréttingum
Authors: Árnason Gísli Einar
Published: February 2022

Stuðningur eftir tannréttingameðferð er mikilvægur þáttur meðferðar til að koma í veg fyrir bakslag og óhagstæðar breytingar á stöðu tanna og biti. Bakslag eftir tannréttingar stafar af togi frá tannhaldsþráðum sem vilja færa tennur aftur í upphaflega stöðu, en getur einnig stafað af óeðlilegum bitkröftum á tennur ef bitafstaða er ekki rétt. Vöxtur kjálka og aldursbreytingar mjúkvefja munnholsins geta einnig haft áhrif á stöðugleika tannréttingameðferðar. Það er því mikilvægt að tannréttingasérfræðingur, sjúklingur og viðkomandi almennur tannlæknir skilji tilgang og ástæðu stuðningsmeðferðar.
Nýting tannlæknaþjónustu á Norðurlöndum
Authors: Rosing Kasper , Suominen Liisa , Árnadóttir Inga B. , Gahnberg Lars , Åstrøm Anne Nordrehaug
Published: February 2022

Nýting eða aðsókn að tannlæknaþjónustu er skilgreind sem hlutfall ákveðins hóps sem fær tannlæknaþjónustu á tilteknu tímabili. Skilgreining þess hvað telst regluleg tannlæknaþjónusta tekur mið af einstaklingsbundnum þörfum. Skipulag tannlæknaþjónustu á Norðurlöndum deilir mörgum sameiginlegum þáttum þar sem hugmyndafræðin er sú að íbúar hafi rétt á jöfnu aðgengi að heilbrigðisþjónustu. Almennt er aðsókn íbúa Norðurlanda að tannlæknaþjónustu góð sem og skilningur á þörf fyrir reglulega tannlæknaþjónustu. Aðsókn sem er lægri en 100% á ársgrundvelli má að hluta til útskýra með því að munn- og tannheilsa íbúa Norðurlanda fer stöðugt batnandi og því eru sífellt fleiri einstaklingar sem ekki þurfa lengur á árlegu eftirliti að halda. Vísbendingar eru þó um að aðrir þættir komi þar einnig við sögu, svo sem tannlæknaótti, félags- og efnahagslegir þættir, erfiðleikar við aðgengi og kostnaður. Sumir þjóðfélagshópar, sérstaklega aldraðir og félagslega viðkvæmari hópar njóta ekki góðs af núverandi kerfi sem skyldi. Þessi staðreynd er bagaleg, bæði frá siðferðilegu og lagalegu sjónarmiði.
Storytelling content, contexts, and controversies
Authors: Mages Wendy K.
Published: February 2022

The performance of autoethnographic storytelling can amplify the voices of those who are often unheard, silenced, or marginalized. Moreover, personal storytelling in appropriate contexts can provide a forum for sharing the previously unspoken or unspeakable that, when shared, can begin to heal the teller and promote social justice and societal change. Yet, not all contexts are are appropriate and not all stories are safe to share. Thus, telling autoethnographic stories can present ethical concerns for which there are no pat answers or one-size-fits-all solutions. This article discusses a few of these concerns.
A novel CD34-specific T-cell engager efficiently depletes acute myeloid leukemia and leukemic stem cells in vitro and in vivo
Authors: Arruda Lucas C. M. , Stikvoort Arwen , Lambert Melanie , Jin Liqing , Rivera Laura Sanchez , Alves Renato M. P. , De Moura Tales Rocha , Mim Carsten , Lehmann Sören , Axelsson-Robertson Rebecca , Dick John E. , Mattsson Jonas , Önfelt Björn , Carlsten Mattias , Uhlin Michael
Published: February 2022

Less than a third of patients with acute myeloid leukemia (AML) are cured by chemotherapy and/or hematopoietic stem cell transplantation, highlighting the need to develop more efficient drugs. The low efficacy of standard treatments is associated with inadequate depletion of CD34+ blasts and leukemic stem cells, the latter a drug-resistant subpopulation of leukemia cells characterized by the CD34+CD38- phenotype. To target these drug-resistant primitive leukemic cells better, we have designed a CD34/CD3 bi-specific T-cell engager (BTE) and characterized its anti-leukemia potential in vitro, ex vivo and in vivo. Our results show that this CD34-specific BTE induces CD34-dependent T-cell activation and subsequent leukemia cell killing in a dose-dependent manner, further corroborated by enhanced T-cell-mediated killing at the singlecell level. Additionally, the BTE triggered efficient T-cell-mediated depletion of CD34+ hematopoietic stem cells from peripheral blood stem cell grafts and CD34+ blasts from AML patients. Using a humanized AML xenograft model, we confirmed that the CD34-specific BTE had in vivo efficacy by depleting CD34+ blasts and leukemic stem cells without side effects. Taken together, these data demonstrate that the CD34-specific BTE has robust antitumor effects, supporting development of a novel treatment modality with the aim of improving outcomes of patients with AML and myelodysplastic syndromes.
Proline-rich tyrosine kinase Pyk2 regulates deep vein thrombosis
Authors: Momi Stefania , Canino Jessica , Vismara Mauro , Galgano Luca , Falcinelli Emanuela , Guglielmini Giuseppe , Taranta Giulia Ciarrocca , Guidetti Gianni Francesco , Gresele Paolo , Torti Mauro , Canobbio Ilaria
Published: February 2022

Deep vein thrombosis results from the cooperative action of leukocytes, platelets, and endothelial cells. The proline-rich tyrosine kinase Pyk2 regulates platelet activation and supports arterial thrombosis. In this study, we combined pharmacological and genetic approaches to unravel the role of Pyk2 in venous thrombosis. We found that mice lacking Pyk2 almost completely failed to develop deep venous thrombi upon partial ligation of the inferior vena cava. Pyk2-deficient platelets displayed impaired exposure of phosphatidylserine and tissue factor expression by endothelial cells and monocytes was completely prevented by inhibition of Pyk2. In human umbilical vein endothelial cells (HUVEC), inhibition of Pyk2 hampered IL-1b-induced expression of VCAM and P-selectin, and von Willebrand factor release. Pyk2-deficient platelets showed defective adhesion on von Willebrand factor and reduced ability to bind activated HUVEC under flow. Moreover, inhibition of Pyk2 in HUVEC strongly reduced platelet adhesion. Similarly, Pyk2-deficient neutrophils were unable to efficiently roll and adhere to immobilized endothelial cells under venous flow conditions. Moreover, platelets and neutrophils from Pyk2- knockout mice showed defective ability to form heterogeneous aggregates upon stimulation, while platelet monocyte interaction occurred normally. Consequently, platelet neutrophil aggregates, abundant in blood of wild-type mice upon inferior vena cava ligation, were virtually undetectable in Pyk2-knockout mice. Finally, we found that expression of Pyk2 was required for NETosis induced by activated platelets. Altogether our results demonstrate a critical role of Pyk2 in the regulation of the coordinated thromboinflammatory responses of endothelial cells, leukocytes and platelets leading to venous thrombosis. Pyk2 may represent a novel promising target in the treatment of deep vein thrombosis.
CCR6 activation links innate immune responses to mucosa-associated lymphoid tissue lymphoma development
Authors: Korona Boguslawa , Korona Dagmara , Zhao Wanfeng , Wotherspoon Andrew C. , Du Ming-Qing
Published: February 2022

The genesis of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) is driven by oncogenic co-operation among immunological stimulations and acquired genetic changes. We previously identified recurrent CCR6 mutations in MALT lymphoma, with majority predicted to result in truncated proteins lacking the phosphorylation motif important for receptor desensitization. Functional consequences of these mutational changes, the molecular mechanisms of CCR6 activation and how this receptor signaling contributes to MALT lymphoma development remain to be investigated. In the present study, we demonstrated that these mutations impaired CCR6 receptor internalization and were activating changes, being more potent in apoptosis resistance, malignant transformation, migration and intracellular signaling, particularly in the presence of the ligands CCL20, HBD2 (human beta defensin 2) and HD5 (human alpha defensin 5). CCR6 was highly expressed in malignant B cells irrespective of the lymphoma sites. HBD2 and CCL20 were constitutively expressed by the duct epithelial cells of salivary glands, and also those involved in lymphoepithelial lesions (LEL) in salivary gland MALT lymphoma. While in the gastric setting, HBD2, and HD5, to a less extent CCL20, were highly expressed in epithelial cells of pyloric and intestinal metaplasia respectively including those involved in LEL, which are adaptive responses to chronic Helicobacter pylori infection. These findings suggest that CCR6 signaling is most likely active in MALT lymphoma, independent of its mutation status. The observations explain why the emergence of malignant B cells and their clonal expansion in MALT lymphoma are typically around LEL, linking the innate immune responses to lymphoma genesis.
The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse
Authors: Kanaji Sachiko , Morodomi Yosuke , Weiler Hartmut , Zarpellon Alessandro , Montgomery Robert R. , Ruggeri Zaverio M. , Kanaji Taisuke
Published: February 2022

Type 2B von Willebrand disease (VWD) is caused by gain-of-function mutations in von Willebrand factor (VWF). Increased VWF affinity for GPIba results in loss of high molecular weight multimers and enhanced platelet clearance, both contributing to the bleeding phenotype. Severity of the symptoms vary among type 2B VWD patients, with some developing thrombocytopenia only under stress conditions. Efforts have been made to study underlying pathophysiology for platelet abnormalities, but animal studies have been limited because of species specificity in the VWF-GPIba interaction. Here, we generated a severe form of type 2B VWD (p.V1316M) knockin mice in the context of human VWF exon 28 (encoding A1 and A2 domains) and crossed them with human GPIba transgenic strain. Heterozygous mutant mice recapitulated the phenotype of type 2B VWD in autosomal dominant manner and presented severe macrothrombocytopenia. Of note, platelets remaining in the circulation had extracytoplasmic GPIba shed-off from the cell surface. Reciprocal bone marrow transplantation determined mutant VWF produced from endothelial cells as the major cause of the platelet phenotype in type 2B VWD mice. Moreover, altered megakaryocyte maturation in the bone marrow and enhanced extramedullary megakaryopoiesis in the spleen were observed. Interestingly, injection of anti-VWF A1 blocking antibody (NMC-4) not only ameliorated platelet count and GPIba expression, but also reversed MK ploidy shift. In conclusion, we present a type 2B VWD mouse model with humanized VWF-GPIba interaction which demonstrated direct influence of aberrant VWF-GPIba binding on megakaryocytes.
El cambio de paradigma de la industria a través de la reingeniería de procesos
Authors: Chica Castro Luis Antonio , Solís Ferrer Hugo Ernesto
Published: February 2022

La historia de la evolución humana, siempre ha estado impactada de cambios de paradigmas (rupturas de modelos, creencias o costumbres), en la búsqueda de mejoras y comodidades para el ser humano. Estos procesos de cambios de paradigma, también sucede con las industrias que inicialmente pudieron surgir como pequeñas empresas familiares o empresas sin mayores aspiraciones, pero que con el correr del tiempo les ha correspondido adaptarse a fin de sobrevivir a la globalización y a otras innovaciones tecnológicas, siendo la reingeniería de proceso una alternativa capaz de repesar los procedimientos que se realizan en las industrias, revisándolos desde cero y con ello rompiendo paradigmas para su aplicación. Sin embargo, es importante conocer cuándo, cómo y porqué implementarla a fin de lograr el éxito de la misma., siendo esto la finalidad de la presente investigación, usando para ello, una metodología basada en el diseño bibliográfico de tipo documental. Obteniendo al final, algunas conclusiones al respecto que dan luz sobre como suceden los cambios de paradigma en la industria al hacer uso de la reingeniería de procesos.
El downsizing como estrategia para la reorganización empresarial: ¿es factible en la era postpandemia COVID-19?
Authors: Nieto Pacheco Albert Joao , Carriel Sevillano Ronny Pedro
Published: February 2022

El objetivo general de esta investigación se basa en analizar el downsizing como una estrategia para la reorganización empresarial y verificar su factibilidad en la post-pandemia. La metodología aplicada es de un diseño bibliográfico de tipo documental. El downsizing a pesar de no ser muy apreciada sobre todo en la actualidad por estar frente a las consecuencias de la pandemia por COVID-19 permite poder enfrentar estas situaciones externas de cambio debido a las restricciones económicas políticas y sociales  impuestas por los países, así como también el poder permanecer activos en el mercado a pesar de las dificultades producto de la disminución de las actividades productivas; De igual manera,  los directivos al conocer mejor y entender las ventajas que esta posee se puede lograr que las personas involucradas mejoren sus puntos de vista y acepten que los cambios organizacionales aplicados están hechos no solo para alcanzar las metas, sino también para lograr una satisfacción laboral entre los empleados, minimizando el estrés laboral, e incrementando los niveles de productividad. Asimismo, el downsizing ha permitido facilitar el manejo de las áreas de trabajo donde existían procesos complejos y que producto de la pandemia tuvieron que reducir sus operaciones, por lo tanto, al disminuir el uso de recursos para optimizar estos procesos se logra ejecutar actividades que permiten el manejo adecuado de las operaciones y aumente la rentabilidad que tanto se ha visto afectada por la presencia del Coronavirus.
Combined Effects of Organic Manures and Chemical Fertilizers on Growth and Yield of Red Capsicum (Capsicum Annuum L.) Grown at Rooftop
Authors: Hossain Md Amir , Md Sadi Khandakar Taki , Jannat Nilima , Rahman MK
Published: February 2022

A pot experiment was conducted to evaluate the effects of organic manures and inorganic fertilizers on the growth and yield of red capsicum (Capsicum annuum L.). It was conducted on rooftop of a building in Bogura town, Bogura. The experiment consisted of twelve treatments with three replications and was laid out in Randomized Complete Block Design (RCBD). Treatments were T1: Control (-OM and -NPK), T2: 4 ton Nafco ha-1 + N23P10K25 kgha-1, T3: 4 ton ACI ha-1 + N23P10K25 kgha-1, T4: 4 ton Trichocompost ha-1 + N23P10K25 kgha-1, T5: 4 ton Kazi Farms ha-1 + N23P10K25 kgha-1, T6: 4 ton Mimpex ha-1 + N23P10K25 kgha-1, T7: 4 ton Mazim ha-1 + N23P10K25 kgha-1, T8: 4 ton McDonald ha-1 + N23P10K25 kgha-1, T9: 4 ton Paragon ha-1 + N23P10K25 kgha-1, T10: 4 ton Kazi Agro ha-1 + N23P10K25 kgha-1, T11: 4 ton Vermicompost ha-1 + N23P10K25 kgha-1 and T12:N46P20K50 kgha-1. Highest plant height (33.81 cm), leaf area (87.22 cm2 plant-1), number of leaves (43 plant-1), number of branches (6 plant-1), number of fruits (11 plant-1), fresh weight (0.60 g plant-1) and dry weight (12.67 g plant-1) were observed in treatment T4: 4 ton Trichocompost ha-1 + N23P10K25 kgha-1. Highest girth (3.18 cm) was observed in treatment T7: 4 ton Mazim ha-1 + N23P10K25 kgha-1. The overall best growth performance was achieved in T4: 4 ton Trichocompost ha-1 + N23P10K25 kgha-1 treatment.
Dhaka Univ. J. Biol. Sci. 31(1): 9-18, 2022 (January)
Heterosis Analysis in Pumpkin (Cucurbitamoschata Duch. Ex. Poir)
Authors: Md Mohsin Gazi , Rahman Md Sajedur , Ahamed Farruk , Md Hasanuzzaman -
Published: February 2022

The research was carried out at Lal Teer Seed Ltd. Gazipur to determine the heterosis of yield and yield contributing traits of pumpkin (Cucurbita moschata Duch. ex Poir.). Six diverse pumpkin parents (viz. CM-1, BARI Mistikumra-1, CM-20 and CM-8) and their 30 F1 hybrids derived from 6X6 diallel including reciprocal were used as research materials. Thirteen genetic parameters [viz. days to first male flower opening, days to first female flower opening, number of flowers (male and female) per plant, fruit length and diameter (cm), fruit weight (kg), flesh thickness (cm), brix (%), number of fruits per plant, number of seeds per fruit, 100-seeds weight (g), yield per plant (kg)] were estimated. The results revealed significantly higher and positive heterosis and expected negative effects for different important characters of pumpkin. The two cross combinations namely; CM-1 × BARI Mistikumra-1 and CM-8 × CM-1 were identified as the promising hybrids which showed the significant higher heterosis, heterobeltiosis and standard heterosis. These finding suggest that cross combinations of indigenous x exotic parents may be beneficial for fruit yield, particularly when used as commercial hybrids. The results showed that these two combinations gave the most promising hybrids (F1), so these two F1 lines were registered in National Seed Board (NSB) of Bangladesh as Hajee F1 and Danesh F1 hybrid varieties.
Dhaka Univ. J. Biol. Sci. 31(1): 117-136, 2022 (January)
Effects of Textile Wastewater on Growth and Yield Components of Rice (Oryza Sativa L.)
Authors: Begum Monoara , Gani Md Nasimul , Alam Md  Didar ul
Published: February 2022

An experiment was conducted to study the effect of textile wastewater on growth and yield components of rice (Oryza sativa L.). The treatments wereT1: Control, T2: Sole RDF (Recommended Dose of Fertilizer) + FW (Fresh Water), T3: 50% RDF + 25% TWW (Textile Waste Water), T4: 50% RDF + 50% TWW, T5: 50% RDF + 75% TWW, T6: 50% RDF + 100% TWW. The highest plant height (134.1 cm), tiller number at maturity stage (344/m2), straw yield (6.94 t/ha),grain yield (4.25 t/ha), panicle number (306/m2), panicle length (24.57cm), number of grain/ panicle (118.5), percent of filled grain/panicle (85.07%) and 1000-grain weight (13.77gm) were found inT2. And the second highest plant height (124.2 cm), tiller number at maturity stage (342/m2), grain yield (3.97 t/ha), panicle number (301/m2), panicle length (24.12cm), number of grain per panicle (117.2), percent of filled grain/panicle (84.17%) and 1000-grain weight (13.37gm) were found in T4.And T5 gave the second highest yield of straw (6.05 t/ha). Although highest values were found in T2, but statistically the achievements indicate that there was little difference between the T2 and T4 treatments. The overall findings of this study indicated that where fresh water is scarce application of 50% RDF along with 50% TWW irrigation may be a good indicator to achieve better growth and yield of rice.
Dhaka Univ. J. Biol. Sci. 31(1): 147-157, 2022 (January)
Seaweed (Hypnea SP.) Supplementation in Feed Play Role in Boosting Immunity of Nile Tilapia (Oreochromis Niloticus)
Authors: Mohammad Mumtahina , Sultana Nahid , Begum Anwara , Naser Md Niamul
Published: February 2022

Hypneasp. is the most common economically potential seaweed species inBangladesh. In this experiment, an initiative was taken to formulate fish feedusing seaweed (Hypneasp.) that can improve the immunity of Nile Tilapia,Oreochromisniloticus. Seaweed was supplemented in different percentages withcommercial feed to evaluate their effects on their serum bactericidal activities. A90-days experiment was conducted under five treatments – T1 (5% seaweed), T2(10% seaweed), T3 (15% seaweed), T4 (20% seaweed) and C (only commercialfeed) with a replica for each. Fish blood was collected, serum was separated fromblood and serum bactericidal activity was tested. Blood serum of 10% seaweedtreated fish showed the highest sensitivity against three bacteria (Bacillus cereus,Salmonella typhimurium, Shigellaflexneri) followed by 5% seaweed which showedsensitivity against Bacillus cereus and slightly against Salmonella typhimuriumandShigellaflexneriand 15% seaweed showed slight bactericidal activity againstBacillus cereus only, whereas, no bactericidal activity was observed for controland 20% seaweed treated fishes. The result indicates that the use of an optimumamount of seaweed supplements can improve the immunity system of Niletilapia which can prevent the growth of bacteria and likely make fishes safe forhuman consumption.
Dhaka Univ. J. Biol. Sci. 31(1): 177-181, 2022 (January)
Adaptation of the Brain Injury Questionnaire of Sexuality Into Bangla and Initial Findings From a Sample Of Bangladeshi Traumatic Brain Injury Patients
Authors: Hossain Md Shahanur , Powell Graham E , Rahman Mohammad Mahmudur
Published: February 2022

Bangladesh is an over populated country with a high incidence of traumaticbrain injury (TBI) for which neuropsychological services are only just emerging.In this context the present study undertook in a culturally sensitive manner totranslate into Bangla (Bengali) the Brain Injury Questionnaire of Sexuality (BIQS)and to present findings from a sample of TBI patients. Standard proceduresincluding back translation for scale adaptation were followed. The Banglaversion of BIQS (BIQS-B) were applied on 30 TBI and 53 healthy sample. Factorand principle component analysis of the BIQS-B yielded three components as inthe original scale explaining 75.3% of the total variance. Reliability is satisfactory,matching that of the English version. The TBI sample scored lower on the BIQS-Bthan did the healthy controls by virtue of not reporting the positive changes insexuality over time that the health controls reported (means of 43.90 vs 52.02, p <0.001). In a very different culture, the factor structure of the BIQS-B is in factsimilar to the English version and has acceptable reliability and validity, hencecontributing to the goal of improving access to services not just in Bangladeshbut in Bangla speaking minority ethnic groups in other countries.
Dhaka Univ. J. Biol. Sci. 31(1): 183-191, 2022 (January)