bluuebunny/crossref_metadata_2025 huggingface dataset:
Selected Natural and Synthetic Agents Effective against Parkinson’s
Disease with Diverse Mechanisms
Authors: Gulcan Hayrettin Ozan
Published: November 2021

:

Similar to other neurodegenerative diseases, Parkinson’s disease (PD) has been extensively investigated with respect to its neuropathological background and possible treatment options. Since the symptomatic outcomes are generally related to dopamine deficiency, the current treatment strate-gies towards PD mainly employ dopaminergic agonists as well as the compounds acting on dopamine metabolism. These drugs do not provide disease modifying properties; therefore alternative drug dis-covery studies focus on targets involved in the progressive neurodegenerative character of PD. This study has aimed to present the pathophysiology of PD concomitant to the representation of drugs and promising molecules displaying activity against the validated and non-validated targets of PD.
Factors Affecting Postpartum Infection: A Systematic Review
Authors: Malmir Maryam , Boroojerdi Narges Azizi , Masoumi Seyedeh Zahra , Parsa Parisa
Published: November 2021

Background:

Puerperal infection is used to describe any bacterial infection of the reproductive
tract after delivery. Identifying the factors affecting postpartum infections can reduce the risk and
complications of such factors and postpartum maternal mortality.

Objective:

This structured study was designed to evaluate factors affecting postpartum infections.

Methods:

In this study, after selecting Scopus, PubMed, SID, and Web of Science electronic databases,
all observational studies (cohort and case-control) available and published in Farsi and English to investigate
factors affecting postpartum infections were searched. The search was performed using the
terms postpartum, infection, wound infection, puerperium, reason, risk factor, and their equivalent
Persian words from 2010 to November 2019 regardless of publication status.

Results:

Out of the 3227 studies obtained, 19 were reviewed after removing irrelevant articles, duplicates
(shared in databases), and animal samples. Age, level of education, delivery method, presence of
episiotomy, anemia due to postpartum hemorrhage, interventions and manipulations during childbirth,
prenatal hygiene, Povidone Iodine usage before delivery to wash the vagina, antibiotic prevention,
increased labor duration, obesity, and the presence of bacteria were common symptoms affecting postpartum
infection.

Conclusion:

In this study, the factors affecting postpartum infection have been identified, some of
which are avoidable. Identifying these factors helps reduce postpartum infections and their complications.
Passive Data Use for Ethical Digital Public Health Surveillance in a Postpandemic World
Authors: Kilgallon John L , Tewarie Ishaan Ashwini , Broekman Marike L D , Rana Aakanksha , Smith Timothy R
Published: November 2021

There is a fundamental need to establish the most ethical and effective way of tracking disease in the postpandemic era. The ubiquity of mobile phones is generating large amounts of passive data (collected without active user participation) that can be used as a tool for tracking disease. Although discussions of pragmatism or economic issues tend to guide public health decisions, ethical issues are the foremost public concern. Thus, officials must look to history and current moral frameworks to avoid past mistakes and ethical pitfalls. Past pandemics demonstrate that the aftermath is the most effective time to make health policy decisions. However, an ethical discussion of passive data use for digital public health surveillance has yet to be attempted, and little has been done to determine the best method to do so. Therefore, we aim to highlight four potential areas of ethical opportunity and challenge: (1) informed consent, (2) privacy, (3) equity, and (4) ownership.
Continuous Glucose Monitoring With Low-Carbohydrate Nutritional Coaching to Improve Type 2 Diabetes Control: Randomized Quality Improvement Program
Authors: Griauzde Dina H , Ling Grace , Wray Daniel , DeJonckheere Melissa , Mizokami Stout Kara , Saslow Laura R , Fenske Jill , Serlin David , Stonebraker Spring , Nisha Tabassum , Barry Colton , Pop-Busui Rodica , Sen Ananda , Richardson Caroline R
Published: November 2021

Background

Type 2 diabetes mellitus (T2DM) is a leading cause of morbidity and mortality globally, with adverse health consequences largely related to hyperglycemia. Despite clinical practice guideline recommendations, effective pharmacotherapy, and interventions to support patients and providers, up to 60% of patients diagnosed with T2DM are estimated to have hemoglobin A1c (HbA1c) levels above the recommended targets owing to multilevel barriers hindering optimal glycemic control.

Objective

The aim of this study is to compare changes in HbA1c levels among patients with suboptimally controlled T2DM who were offered the opportunity to use an intermittently viewed continuous glucose monitor and receive personalized low-carbohydrate nutrition counseling (<100 g/day) versus those who received usual care (UC).

Methods

This was a 12-month, pragmatic, randomized quality improvement program. All adult patients with T2DM who received primary care at a university-affiliated primary care clinic (N=1584) were randomized to either the UC or the enhanced care (EC) group. Within each program arm, we identified individuals with HbA1c >7.5% (58 mmol/mol) who were medically eligible for tighter glycemic control, and we defined these subgroups as UC–high risk (UC-HR) or EC-HR. UC-HR participants (n=197) received routine primary care. EC-HR participants (n=185) were invited to use an intermittently viewed continuous glucose monitor and receive low-carbohydrate nutrition counseling. The primary outcome was mean change in HbA1c levels from baseline to 12 months using an intention-to-treat difference-in-differences analysis comparing EC-HR with UC-HR groups. We conducted follow-up semistructured interviews to understand EC-HR participant experiences with the intervention.

Results

HbA1c decreased by 0.41% (4.5 mmol/mol; P=.04) more from baseline to 12 months among participants in the EC-HR group than among those in UC-HR; however, only 61 (32.9%) of 185 EC-HR participants engaged in the program. Among the EC-HR participants who wore continuous glucose monitors (61/185, 32.9%), HbA1c was 1.1% lower at 12 months compared with baseline (P<.001). Interviews revealed themes related to EC-HR participants’ program engagement and continuous glucose monitor use.

Conclusions

Among patients with suboptimally controlled T2DM, a combined approach that includes continuous glucose monitoring and low-carbohydrate nutrition counseling can improve glycemic control compared with the standard of care.
Use of Mobile Apps for Self-care in People With Parkinson Disease: Systematic Review
Authors: Lee JuHee , Yeom Insun , Chung Misook L , Kim Yielin , Yoo Subin , Kim Eunyoung
Published: November 2021

Background

Self-care is essential for people with Parkinson disease (PD) to minimize their disability and adapt to alterations in physical abilities due to this progressive neurodegenerative disorder. With rapid developments in mobile technology, many health-related mobile apps for PD have been developed and used. However, research on mobile app–based self-care in PD is insufficient.

Objective

This study aimed to explore the features and characteristics of mobile apps for self-care in people with PD.

Methods

This study was performed sequentially according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, Web of Science, and PsycINFO were searched in consultation with a librarian on June 8, 2021. We used keywords including ”Parkinson disease” and ”mobile.”

Results

A total of 17 studies were selected based on the inclusion criteria, including 3 randomized controlled trials and 14 observational studies or quasi-experimental studies. The use of mobile apps for self-care in people with PD focused on symptom monitoring, especially motor symptoms. Motor symptoms were objectively measured mainly through the sensors of smartphones or wearable devices and task performance. Nonmotor symptoms were monitored through task performance or self-reported questionnaires in mobile apps. Most existing studies have focused on clinical symptom assessment in people with PD, and there is a lack of studies focusing on symptom management.

Conclusions

Mobile apps for people with PD have been developed and used, but strategies for self-management are insufficient. We recommend the development of mobile apps focused on self-care that can enhance symptom management and health promotion practices. Studies should also evaluate the effects of mobile apps on symptom improvement and quality of life in people with PD.

Trial Registration

PROSPERO International Prospective Register of Systematic Reviews CRD42021267374; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021267374.
Leveraging Large-Scale Electronic Health Records and Interpretable Machine Learning for Clinical Decision Making at the Emergency Department: Protocol for System Development and Validation
Authors: Liu Nan , Xie Feng , Siddiqui Fahad Javaid , Ho Andrew Fu Wah , Chakraborty Bibhas , Nadarajan Gayathri Devi , Tan Kenneth Boon Kiat , Ong Marcus Eng Hock
Published: November 2021

Background

There is a growing demand globally for emergency department (ED) services. An increase in ED visits has resulted in overcrowding and longer waiting times. The triage process plays a crucial role in assessing and stratifying patients’ risks and ensuring that the critically ill promptly receive appropriate priority and emergency treatment. A substantial amount of research has been conducted on the use of machine learning tools to construct triage and risk prediction models; however, the black box nature of these models has limited their clinical application and interpretation.

Objective

In this study, we plan to develop an innovative, dynamic, and interpretable System for Emergency Risk Triage (SERT) for risk stratification in the ED by leveraging large-scale electronic health records (EHRs) and machine learning.

Methods

To achieve this objective, we will conduct a retrospective, single-center study based on a large, longitudinal data set obtained from the EHRs of the largest tertiary hospital in Singapore. Study outcomes include adverse events experienced by patients, such as the need for an intensive care unit and inpatient death. With preidentified candidate variables drawn from expert opinions and relevant literature, we will apply an interpretable machine learning–based AutoScore to develop 3 SERT scores. These 3 scores can be used at different times in the ED, that is, on arrival, during ED stay, and at admission. Furthermore, we will compare our novel SERT scores with established clinical scores and previously described black box machine learning models as baselines. Receiver operating characteristic analysis will be conducted on the testing cohorts for performance evaluation.

Results

The study is currently being conducted. The extracted data indicate approximately 1.8 million ED visits by over 810,000 unique patients. Modelling results are expected to be published in 2022.

Conclusions

The SERT scoring system proposed in this study will be unique and innovative because of its dynamic nature and modelling transparency. If successfully validated, our proposed solution will establish a standard for data processing and modelling by taking advantage of large-scale EHRs and interpretable machine learning tools.

International Registered Report Identifier (IRRID)

DERR1-10.2196/34201
The Use of a Computerized Cognitive Assessment to Improve the Efficiency of Primary Care Referrals to Memory Services: Protocol for the Accelerating Dementia Pathway Technologies (ADePT) Study
Authors: Kalafatis Chris , Modarres Mohammad Hadi , Apostolou Panos , Tabet Naji , Khaligh-Razavi Seyed-Mahdi
Published: November 2021

Background

Existing primary care cognitive assessment tools are crude or time-consuming screening instruments which can only detect cognitive impairment when it is well established. Due to the COVID-19 pandemic, memory services have adapted to the new environment by moving to remote patient assessments to continue meeting service user demand. However, the remote use of cognitive assessments has been variable while there has been scant evaluation of the outcome of such a change in clinical practice. Emerging research in remote memory clinics has highlighted computerized cognitive tests, such as the Integrated Cognitive Assessment (ICA), as prominent candidates for adoption in clinical practice both during the pandemic and for post-COVID-19 implementation as part of health care innovation.

Objective

The aim of the Accelerating Dementia Pathway Technologies (ADePT) study is to develop a real-world evidence basis to support the adoption of ICA as an inexpensive screening tool for the detection of cognitive impairment to improve the efficiency of the dementia care pathway.

Methods

Patients who have been referred to a memory clinic by a general practitioner (GP) are recruited. Participants complete the ICA either at home or in the clinic along with medical history and usability questionnaires. The GP referral and ICA outcome are compared with the specialist diagnosis obtained at the memory clinic. The clinical outcomes as well as National Health Service reference costing data will be used to assess the potential health and economic benefits of the use of the ICA in the dementia diagnosis pathway.

Results

The ADePT study was funded in January 2020 by Innovate UK (Project Number 105837). As of September 2021, 86 participants have been recruited in the study, with 23 participants also completing a retest visit. Initially, the study was designed for in-person visits at the memory clinic; however, in light of the COVID-19 pandemic, the study was amended to allow remote as well as face-to-face visits. The study was also expanded from a single site to 4 sites in the United Kingdom. We expect results to be published by the second quarter of 2022.

Conclusions

The ADePT study aims to improve the efficiency of the dementia care pathway at its very beginning and supports systems integration at the intersection between primary and secondary care. The introduction of a standardized, self-administered, digital assessment tool for the timely detection of neurodegeneration as part of a decision support system that can signpost accordingly can reduce unnecessary referrals, service backlog, and assessment variability.

Trial Registration

ISRCTN 16596456; https://www.isrctn.com/ISRCTN16596456

International Registered Report Identifier (IRRID)

DERR1-10.2196/34475
Patient Engagement in the Design of a Mobile Health App That Supports Enhanced Recovery Protocols for Cardiac Surgery: Development Study (Preprint)
Authors: Chudyk Anna M , Ragheb Sandra , Kent David , Duhamel Todd A , Hyra Carole , Dave Mudra G , Arora Rakesh C , Schultz Annette SH
Published: November 2021

BACKGROUND

Despite the importance of their perspectives, end users (eg, patients, caregivers) are not typically engaged by academic researchers in the development of mobile health (mHealth) apps for perioperative cardiac surgery settings.

OBJECTIVE

The aim of this study was to describe a process for and the impact of patient engagement in the development of an mHealth app that supports patient and caregiver involvement with enhanced recovery protocols during the perioperative period of cardiac surgery.

METHODS

Engagement occurred at the level of consultation and took the form of an advisory panel. Patients who underwent cardiac surgery (2017-2018) at St. Boniface Hospital (Winnipeg, Manitoba) and their caregivers were approached for participation. A qualitative exploration determined the impact of patient engagement on the development (ie, design and content) of the mHealth app. This included a description of (1) the key messages generated by the advisory panel, (2) how key messages were incorporated into the development of the mHealth app, and (3) feedback from the developers of the mHealth app about the key messages generated by the advisory panel.

RESULTS

The advisory panel (N=10) generated 23 key messages to guide the development of the mHealth app. Key design-specific messages (n=7) centered around access, tracking, synchronization, and reminders. Key content-specific messages (n=16) centered around medical terms, professional roles, cardiac surgery procedures and recovery, educational videos, travel, nutrition, medications, resources, and physical activity. This information was directly incorporated into the design of the mHealth app as long as it was supported by the existing functionalities of the underlying platform. For example, the platform did not support the scheduling of reminders by users, identifying drug interactions, or synchronizing with other devices. The developers of the mHealth app noted that key messages resulted in the integration of a vast range and volume of information and resources instead of ones primarily focused on surgical information, content geared toward expectations management, and an expanded focus to include caregivers and other family members, so that these stakeholders may be directly included in the provision of information, allowing them to be better informed, prepare along with the patient, and be involved in recovery planning.

CONCLUSIONS

Patient engagement may facilitate the development of a detail-oriented and patient-centered mHealth app whose design and content are driven by the lived experiences of end users.
Perancangan Kendali Formasi pada Multi-Robot Roda Omni dengan Kemampuan Menghindari Tabrakan
Authors: Faisal Wahab
Published: November 2021

Pada makalah ini dirancang sebuah kendali formasi terdistribusi menggunakan multi-robot roda omni (Omni Directional Wheel Mobile Robot, OMR) dengan kemampuan menghindari tabrakan antar OMR saat membentuk sebuah formasi. Kendali formasi menggunakan algoritme konsensus yang terdiri atas empat buah layer, yaitu layer tracking, layer konsensus, layer behavior, serta layer fisik robot. Layer tracking digunakan untuk mengarahkan posisi OMR pada virtual center yang telah ditentukan. Pada layer konsensus dirancang pengendali pada tingkat robot. Pengendali ini merupakan penjabaran dari algoritme konsensus. Layer behavior digunakan untuk menambah metode penghindar tabrakan antar OMR saat membentuk formasi. Penghindar rintangan menggunakan metode Stipanovic. Pada layer fisik robot, digunakan OMR dengan konfigurasi tiga buah roda omni. OMR yang digunakan berjumlah empat buah. Pengendali yang telah dirancang disimulasikan dengan menggunakan peranti lunak MATLAB. Hasil simulasi menunjukkan bahwa pengendali yang diterapkan pada OMR telah berhasil membentuk formasi yang diinginkan, yaitu persegi dan belah ketupat, serta dalam perjalanan membentuk formasi tersebut, setiap OMR dapat menjaga jarak sehingga tidak terjadi tabrakan dengan berbagai topologi komunikasi dan bentuk formasi.
Los modelos del pasado en los escritos retóricos de Cicerón: un estudio sobre su valor moral y formativo
Authors: Bellido Francisco J.
Published: November 2021

Defiendo que lo novedoso de la concepción de Cicerón de los modelos basados en personajes del pasado consistió en conferirles habilidades que podían aplicarse a las disputas legales y políticas de Roma y, al mismo tiempo, mejorar el desempeño de los oradores jóvenes y aprendices mediante un modelo mixto de retórica. La destreza técnica y la prudencia práctica de estas autoridades para advertir aspectos cruciales en casos particulares y adaptarse a circunstancias adversas sirven como ejemplos para los oficios del rétor y del abogado. Esas dos características, y no el amplio conocimiento o la fama que estos personajes alcanzaron, llevaron a Cicerón a reconocer a ciertos oradores y pensadores como fuentes de inspiración moral y formativa.
Juicio, relación múltiple y la teoría cognitivista de las proposiciones
Authors: Vidal Javier
Published: November 2021

Según la teoría cognitivista, las proposiciones son tipos de actos predicativos, y un agente lleva a cabo una predicación cada vez que juzga o asevera algo. Ahora bien, la versión predominante de dicha teoría establece que el juicio es una actitud cognitiva hacia un contenido proposicional genuino, lo que significa que se lo entiende como una relación dual entre un agente y una proposición. Tras mostrar algunos problemas con esta versión, argumentaré a favor de una teoría cognitivista de las proposiciones en la que el juicio se entiende como una relación múltiple entre un agente y entidades del mundo tales como objetos, propiedades y relaciones.
VALIDATION ANALYSIS OF CONTEXTUAL-BASED COMIC LEARNING MEDIA DEVELOPMENT ON TORQUE CONCEPT MATERIALS IN SMA
Authors:   Tadris (Pendidikan) Fisika, IAIN Palangka Raya, Normilawati Normilawati , Aulia Maryam ,   Tadris (Pendidikan) Fisika, IAIN Palangka Raya, Yuliani Hadma ,   Tadris (Pendidikan) Fisika, IAIN Palangka Raya, Annovasho Jhelang ,   Tadris (Pendidikan) Fisika, IAIN Palangka Raya, Mardaya Mardaya ,   Tadris (Pendidikan) Fisika, IAIN Palangka Raya
Published: November 2021

Lack of student interest in studying physics because in addition to lessons that are considered difficult, learning media are also still less attractive so that learning media are needed that can make students interested in a pleasant learning atmosphere that is supported by learning that connects material with applications that occur in everyday life such as contextual based physics comics. The purpose of this research is to produce a product in the form of contextual-based comic media on torsional concept material in high school. The analytical technique used is descriptive qualitative analysis to be able to describe the validation of the questionnaire from the validators of material experts and media experts. This study uses Research and Development (R&D) research with a 4-D model consisting of define, design, development, and dissemination stages. The research is limited due to time constraints so that it only reaches the development stage. The results of the study obtained a material validity value of 4.05 or 81% which was included in the very feasible category and the media validity value of 4.5 or 90% which was included in the very feasible category. From the results of the study, it can be concluded that the development of contextual-based comic learning media on torsional concept material in high school is very feasible to be used as a learning resource. Keywords: Validation, learning media, comic, and contextual
ANALYSIS OF GREENHOUSE EFFECT CONCEPT MASTERING ON PHYSICS EDUCATION STUDENTS FOR THE 2016 UNIVERSITY OF JEMBER
Authors:   Jember University, Sudarti Sudarti , Nur Laili Sherly ,   Jember University, Laksmiari Karina ,   Jember University
Published: November 2021

The greenhouse effect is the process by which radiation from a planet's atmosphere warms a planet's surface to a temperature higher than what it would be if there were no atmosphere. Catherine Gautier (2006) in a class shows that students are often unaware of their misunderstanding of their representations when compared to scientific representations. One of the factors that can influence misconceptions in students is an error in interpreting the meaning conveyed. This study aims to test the mastery of the concept of the greenhouse effect on students. The sample used in this study was 50 students of Physics Education class of 2016 at the University of Jember who were taking their fourth semester. Methods The research is carried out with quantitative methods. The method of collecting data is a questionnaire obtained from open questions (in the form of essays) posed to students of Physics Education class 2016 at the University of Jember, totaling 10 questions. Based on the results of data analysis, it can be concluded that there are students who have misconceptions about the greenhouse effect. Keywords: Atmosphere, Greenhouse Effect, Misconception, Temperature.
Functional Group Evaluation of Hydrogenated Vegetable Oil Using FTIR Method
Authors: Kalaimani Priya Subramanian
Published: November 2021

Abstract: This study aimed to predict the functional group changes in the natural form to hydrogenated form of vegetable oils using FTIR spectroscopic method. The edible oil, which are palm oil, groundnut oil, sesame oil, and vanaspathi(hydrogenated vegetable oil) were observed with relative intensities of the peak and characteristic area percentage of peaks. It is found that trans fatty acids at the peak of 966.34cm-1 in the region of 980-960cm-1 strong C=C bending vibration due to the presence of alkene disubstituted (trans) observed in the hydrogenated form of vegetable oil. Because the nutritional composition of the vegetable oil is intensely reduced and long-term consumption will bringadversative health problems for humans. Keywords: FTIR, Palm oil, Groundnut oil, Sesame oil, Vanaspathi, Transfats
Keresahan komika terhadap pelanggaran aturan pemerintah dalam menghadapi wabah Covid-19: Analisis sosiocultural practice
Authors: Putri Lasri Maisa , Ramadhan Syahrul
Published: November 2021

Pandemi Covid-19 telah meresahkan seluruh dunia, termasuk Indonesia. Salah satu kebijakan yang diberlakukan di Indonesia untuk menekan penularan Covid-19 adalah PSBB. PSBB yang telah digagas oleh pemerintah tidak membuat masyarakat sadar akan bahaya Covid-19, sehingga menimbulkan kekhawatiran terhadap penyebarannya yang begitu cepat. Penelitian ini bertujuan untuk mengkaji keresahan komika terhadap masyarakat Indonesia yang melanggar aturan pemerintah dalam menghadapi wabah Covid-19, kajian ini dilihat dari perspektif Sosiocultural Practice Norman Fairclough. Sumber data penelitian adalah video dalam konten Dewan Perwakilan Omel-Omel (DPO) yang diunggah di Instagram @bintangemon tentang corona. Data penelitian ini berupa kata atau kalimat yang diucapkan Bintang Emon dalam video #DPOcorona dan #DPOcorona2. Teknik pengumpulan data menggunakan teknik simak dan catat. Analisis data dengan cara mengelompokkan data sesuai dengan kategori yang digunakan. Kemudian, dilakukan pemaparan data yang menggunakan teknik analisis wacana kritis model Norman Fairclough dari sosial-budaya dimensi praktik yang meliputi situasional, institusional, dan sosial. Langkah terakhir adalah melakukan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa aspek situasional, aspek institusional, dan aspek sosial memang sengaja dibuat dan diunggah oleh Bintang Emon. Hal ini dilakukan untuk mengungkapkan keresahan terhadap masyarakat Indonesia yang tidak mengindahkan himbauan pemerintah tentang penerapan sistem Pembatasan Sosial Berskala Besar (PSBB). Selain itu, keresahannya tentang oknum-oknum yang menyalahgunakan alat-alat kesehatan serta oknum yang mengambil kesempatan untuk meraih keuntungan pribadi di tengah pandemi Covid-19 ini.
A corpus-driven collocation analysis of degree adverb very, really, quite, and pretty
Authors: Indhiarti Tantri Refa , Chaerunnisa Erwanda Resti
Published: November 2021

Degree adverb merupakan elemen intensifiers sebagai sarana bagi penutur bahasa untuk membuat ucapannya lebih ekspresif. Elemen ini memberikan informasi tentang berapa banyak dan sejauh mana. Setiap adverbial memiliki preferensi sendiri dalam hal kolokasi dan prosodi semantik yang muncul. Penelitian berikut ini membahas pola kolokasional dan prosodi semantik adverbial very, really, quite, dan pretty di Blog Authorship Corpus. Dengan demikian pendekatan kualitatif digunakan dalam penelitian ini dengan dibantu metode korpus dalam mengumpulkan dan menganalisis data, serta perangkat lunak korpus WordSmith 4.0. Sumber data berasal dari Blog Authorship Corpus, suatu korpus yang belum mengalami proses anotasi, yang dapat dengan mudah diakses melalui situs web. Hasil analisis menunjukkan bahwa semua adverbial bersatu dengan kata-kata dari kelas kata sifat, kata kerja dan kata keterangan. Dalam hal ini, really dan quite terlihat bersebelahan dengan kata kerja, dan pada saat yang sama really juga berkolokasi dengan preposisi dalam kasus tertentu. Kedua jenis adverbial tersebut sebagian besar terjadi pada posisi medial, dibedakan dari kolokasi yang membentuk beberapa pola berbeda. Prosodi semantik yang positif meliputi adverbial very dan quite, sementara prosodi semantik yang netral dan negatif meliputi adverbial pretty dan really.
Penolakan Dominika Terhadap Pemberlakuan Mata Uang SUCRE
Authors: Maghfiroh Selviana Lailil
Published: November 2021

Artikel ini bertujuan untuk mengetahui mengapa Dominika membuat kebijakan untuk menolak mata uang SUCRE. Mata uang tersebut merupakan sebuah regional currency yang telah dicetuskan oleh ALBA untuk mengurangi ketergantungan terhadap dolar AS. ALBA menganggap SUCRE sangat penting untuk diikuti oleh para anggotanya karena akan memberikan manfaat secara ekonomis. Penelitian ini menjelaskan keputusan Dominika menolak integrasi moneter SUCRE yang dianalisis dari berbagai faktor internal dan eksternal berdasarkan teori The Formulation of Foreign Policy Objectives oleh Keith R. Legg dan James F. Morisson. Artikel ini menggunakan metode eksplanatif kualitatif dengan menggunakan teknik pengumpulan data sekunder dalam prosesnya. Hasilnya menunjukkan bahwa keputusan Dominika tidak menerapkan SUCRE sebagai regional currency dipengaruhi faktor internal dan eksternal. Faktor internal tersebut yaitu: 1) Jika Dominika mengadopsi mata uang tersebut maka akan bertentangan dengan keanggotaannya di OECS, 2) Keadaan ekonomi Dominika yang rendah membuat negara tersebut tidak dapat memenuhi persyaratan di SUCRE yang berdampak pada ketidakleluasaan untuk mempengaruhi kebijakan moneter terhadap mata uang tersebut. Selain itu, faktor eksternal yang juga menjadi pertimbangan terbatasnya pangsa pasar dominika di SUCRE.
Penguatan Kapasitas Kelembagaan Program Kota Layak Anak dalam Penanganan Permasalahan Kekerasan Seksual Anak di Kota Surakarta
Authors: Ningrum Cintia Cahya , Yuliani Sri
Published: November 2021

Penelitian ini berfokus menjelaskan bagaimana langkah yang mesti dilakukan dalam penguatan program Kebijakan Kota Layak Anak sebagai upaya penanganan kekerasan seksual anak di Kota Surakarta. Kota Layak Anak sendiri merupakan salah satu bentuk Kebijakan Perlindungan Anak yang dibuat pada tahun 2006, dimana Kota Surakarta menjadi salah satu pilot project dalam program ini. Pada tahun 2017 Kota Surakarta telah mendapatkan penghargaan untuk Kategori Utama, namun kasus seperti Kekerasan Seksual Anak (KSA) cenderung mengalami peningkatan tiap tahunnya. Dalam program Kota Layak Anak terdapat indikator Penguatan Kelembagaan dan 5 indikator Klaster Hak Anak yang harus dipenuhi. Indikator Perlindungan Khusus menjadi salah satu indikator yang memiliki penilaian lebih rendah dibanding ke-4 indikator lainnya. Dengan menggunakan menggunakan metode deskriptif kualitatif, penelitian ini menghasilkan temuan bahwa guna memaksimalkan penguatan program Kota Layak Anak dalam menangani masalah kekerasan seksual terhadap anak diperlukan adanya pembaharuan Peraturan Daerah Kota Surakarta tentang Perlindungan Anak, adanya konsistensi anggaran, keikutsertaan Dinas dalam pelatihan KHA bersertifikat, serta diadakannya rapat koordinasi rutin antar stakeholder yang terlibat.
Fenomena Konstruksi Politik Dinasti pada Pilkada Serentak Tahun 2020 di Kabupaten Batang Hari
Authors: Muhammad Hatta Abdi , Anggara Dony
Published: November 2021

Tulisan ini berfokus mengkaji fenomena konstruksi politik dinasti di Batang Hari, khususnya pada momentum Pilkada serentak tahun 2020. Terdapat upaya pelanggengan kekuasaan dari dua tokoh elit politik melalui representasi mereka dengan pola kekerabatan politik. Metode deskriptif kualitatif digunakan untuk menganalisis secara mendalam terhadap fenomena yang terjadi dengan memanfaatkan data sekunder dan data primer dari berbagai informan. Berbagai data dianalisis secara interaktif dan dikonfirmasi keabsahannya kemudian disajikan secara analisis deskriptif. Hasil penelitian menunjukan bahwa konstruksi politik dinasti di Kabupaten Batang Hari mudah terbentuk bukan saja disebabkan faktor ekonomi namun juga disebabkan karakteristik masyarakat yang masih tradisional. Keadaan sosial ekonomi masyarakat yang memperihatinkan selama kurang lebih 20 tahun secara tidak langsung mendukung kelanggengan pelokalan politik. Dalam kurun waktu tersebut berdampak pada terbentuknya budaya politik masyarakat yang pragmatis. Hal-hal yang menyangkut rasionalitas (visi misi, program kerja, pembangunan) dalam memilih dipaksa diabaikan karena kondisi sosial ekonomi sehingga menjadikan masyarakat lebih menyukai hal-hal yang praktis (politik uang) yang dapat memenuhi kebutuhan mereka secara langsung.
Strategi Diplomasi Ekonomi Indonesia dalam Menjaga Stabilitas Neraca Perdagangan di Tengah Pandemi Covid-19
Authors: Nabilla Natsha
Published: November 2021

Sejak pertama kali muncul di kota Wuhan, Tiongkok, COVID 19 telah diumumkan oleh World Health Organization (WHO) sebagai suatu darurat kesehatan dunia. Bagi Indonesia pandemi COVID 19 telah menyebabkan neraca perdagangan mengalami defisit sejumlah 344,7 juta USD per April 2020. Situasi akibat pandemi COVID 19 membuat Indonesia membutuhkan strategi baru dalam menjaga arus lalu lintas perdagangan baik domestik maupun internasional. Dalam tulisan ini akan dibahas mengenai strategi baru dalam diplomasi ekonomi Indonesia sebagai instrumen dalam meningkatkan perdagangan dan investasi internasional. Tulisan ini juga akan membatasi penelitian di masa pemerintahan Presiden Joko Widodo baik sebelum maupun pada saat pandemi COVID-19. Adapun dalam pembahasannya akan digunakan konsep tahapan strategi diplomasi ekonomi negara berkembang dari Kishan Rana. Berdasarkan penelitian ditemukan bahwa beberapa dari strategi Indonesia yang pada masa sebelum COVID 19 mulai mengalami kesulitan. Akibatnya Indonesia menggunakan strategi baru yang disesuaikan dengan keadaan pada saat pandemi COVID 19 terjadi. Meskipun begitu, secara garis besar, strategi yang digunakan tetap mencakup 4 tahapan yaitu Economic Salesmanship, Networking, Image Branding/Promotion, dan Regulation Management.
Akun Twitter BNPB_RI Sebagai Media Komunikasi Pemerintah Indonesia di Masa Pandemi Covid-19
Authors: Putri Pratiwi Vindhi , Rahmawati Dian Eka , Purwaningsih Titin
Published: November 2021

Adanya pandemi COVID-19 secara global menjadi tantangan sendiri khususnya bagi pemerintah Indonesia. Salah satunya dalam penyampaian informasi terkait dengan COVID-19. Adanya pandemi besar ini juga menghasilkan berbagai informasi-informasi yang mampu menciptakan ketegangan bagi masyarakat. Oleh karenanya perlu adanya komunikasi pemerintah yang efektif dan tepat kepada masyarakat terkait dengan pandemic ini. Sehingga tujuan penelitian ini untuk melihat komunikasi pemerintah di masa pandemi melalui akun Twitter @BNPB_Indonesia dengan mengetahui intensitas komunikasi pemerintah dan melihat hubungan interaksi komunikasi pemeirntah melalui akun Twitter @BNPB_Indonesia. Penelitian ini menggunakan metode pendekatan penelitian kualitatif dan analisis data diolah dengan bantuan software NVivo 12 Plus. Data diperoleh melalui akun Twitter @BNPB_indonesia. Dari hasil penelitian diperoleh komunikasi yang dibangun oleh pemerintah di masa pandemic COVID-19 melalui akun Twitter @BNPB_indonesia aktif menyampaikan informasi kepada public dan informasi tersebut dapat diterima oleh public dengan baik. Sehingga hal ini melihatkan komunikasi pemerintah yang bersifat eksternal dimana memiliki fungsi to managing people.
Indonesian Democracy as A Model for Egypt after The Arab Spring
Authors: Sahide Ahmad , Satris Rezki
Published: November 2021

The Arab Spring in 2011 opened the way for democratization in some Arab countries, including Egypt. Egypt succeeded in overthrowing Hosni Mubarak as the president, but Egypt failed in consolidating democracy after holding a general election in 2012. The main factors of the failure in consolidating democracy in Egypt come from internal and external factors. The internal factor was that Egypt had not been ready for democracy , whereas the external factor was  foreign intervention due to national interest. This article analyzes the failure of democratization in Egypt by using Jack Snyder and Georg Sorensen’s theory. In the last part of this article, the writer suggested that Egypt should have learned how to consolidate democracy from Indonesia. Indonesia is the best model of democracy for Egypt due to some reasons. The first one is Indonesia and Egypt near a culturally (religious approach), and the second one is Indonesia's success, as the majority Muslim state, in consolidating democracy since 1998.
Dampak Keberadaan Penderita Gangguan Jiwa Terhadap Ketahanan Wilayah Kabupaten Jombang
Authors: Hakim Febiadi Faisal
Published: November 2021

Penelitian ini bertujuan menjelaskan dampak keberadaan penderita gangguan jiwa terhadap ketahanan wilayah di Kabupaten Jombang. Tingginya jumlah penderita gangguan jiwa di wilayah tersebut berdampak pada terancamnya ketahanan wilayah yang berpotensi dapat mengganggu ketertiban sosial yang ada. Pelaksanaan penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan etnografi. Penelitian ini berjenis deskriptif kualitatif, dengan menitikberatkan pada 3 jenis informan sebagai subjek penelitian yakni: penderita gangguan jiwa, informan tahu (keluarga, tokoh masyarakat/agama dan masyarakat lingkungan sosial) dan informan ahli (dokter spesialis kesehatan jiwa) melalui teknik purposive sampling. Teknik pengumpulan data yang digunakan adalah melalui studi wawancara dan studi dokumentasi. Sebagai hasilnya, fenomena gangguan jiwa di Kabupaten Jombang memberikan dampak negatif terhadap ketahanan wilayah tersebut terutama pada (1) gatra ekonomi, yaitu hilangnya kemampuan produktivitas diri sehingga berdampak pada penurunan ketahanan ekonomi keluarga dan rendahnya ketahanan ekonomi wilayah, (2) gatra sosial, yaitu isolasi sosial, adanya tindakan pemasungan dan melekatnya stigma dan labelling gila pada mantan penderita gangguan jiwa, (3) gatra keamanan, yaitu munculnya teror akibat hilangnya ketertiban sosial masyarakat dan beredarnya berita hoax.
The Isolation, Selection and Determination of Endophytic Bacteria from Bamboo, Gamal, Tulsi, and Alamanda
Authors: Hermanu Triwidodo  , Listihani Listihani
Published: November 2021

Endophytic bacteria have many benefits, including increasing plant growth by producing phytohormones, increasing the production of mineral absorption, nitrogen fixation, reducing damage due to weather changes and increasing plant resistance to disease. Based on the above, it is necessary to select endophytic bacteria from various plants to be used as biocontrol agents. This study aims to obtain endophytic bacterial isolates that have the potential as biocontrol agents and plant growth supporters from bamboo shoots, Gamal, Tulsi, Lotus, and Alamanda. This research method includes sampling, endophytic bacteria isolation, hypersensitive, hemolysis, phosphate solvent, chitinolytic, proteolytic, and antagonist tests. Isolation of endophytic bacteria in 5 plants using 22 plant parts had a diversity of isolates. The isolated plant parts produced 1 to 7 isolates that had different morphology. The total isolates obtained were 59 isolates. In antagonistic observations, there was one isolate of endophytic bacteria that showed a clear zone when tested together with S. rolfsii, namely the isolate with code A24 from allamanda flower. From the data obtained, it is known that the endophytic bacterial isolates had an effect on inhibiting the growth of the pathogenic fungus S. roflsii, the endophytic bacterial isolates Consortium, A21 and the endophytic bacterial isolates A22 had no incidence of disease, while the bacterial isolates T00 (Bx) with an average disease incidence of 40% and 30% disease intensity. Meanwhile isolates A23, A24 and A25 had an average disease incidence ranging from 13.3%-26.6%, while controls had the highest disease incidence, namely 53.3% and disease intensity 66.6%.
Petro-Nostalgia and the Politics of Yellow Vests Canada
Authors: Tewksbury Doug
Published: November 2021

Background: This article presents a critical discourse analysis of the conservative political organization Yellow Vests Canada and its 100,000-plus member Facebook group (now deplatformed) to theorize far-right groups that harness pro-fossil-fuel/anti-environmental discourses to ideologically cultivate a broader assemblage of traditionally ultra-conservative political positions.

Analysis: Yellow Vests Canada commonly utilized “petro-nostalgic” discourses, highly ideological beliefs that tie fossil fuels to a mythological nostalgia for an era of unbridled extraction and consumption, but also to this era’s hegemonic white supremacy, heteronormativity, masculinity, and settler-colonial nationalism.

Conclusions and implications: Understanding far-right petro-political groups is imperative for environmental humanities researchers. The recent growth of these groups presents an alarming threat to progressive and equitable sociocultural politics, but especially to more environmentally sustainable government policies and a post-fossil-fuel future.
Fire and Climate: Connecting the Dots in British Columbia News Media
Authors: Earle Heather , Gunster Shane
Published: November 2021

Background: Extreme weather events are intensifying with climate change, offering opportunities to raise the public urgency of this issue. The media’s role in communicating this connection is crucial. 
Analysis: This article analyzes media coverage of wildfires over a nine-year period in British Columbia focusing on how they are linked to climate change, in particular, during the 2017 and 2018 record-breaking fire seasons. 
Conclusion and implications: In media coverage in British Columbia, there is a marked absence of a link between climate change and wildfires and a tendency for connections to be tokenistic, decontextualized, and normalizing. More provocative narratives developed by various public figures that locate wildfires within broader narratives of climate crisis offer more compelling accounts.
Contexte : À cause du changement climatique, les événements climatiques extrêmes sont en train de devenir plus intenses. Dans les circonstances, il devient pertinent de soulever l’urgence publique de cet enjeu, et les médias pourraient jouer un rôle crucial pour le communiquer.
Analyse : Cet article analyse la couverture médiatique de feux de forêt sur une période de neuf ans en Colombie-Britannique, particulièrement durant les saisons des feux de 2017 et 2018 qui ont battu tous les records. L’article met l’accent sur comment ces incendies sont reliés au changement climatique.
Conclusions et implications : Dans la couverture médiatique en Colombie-Britannique, on néglige de montrer les liens qui existent entre le changement climatique et les feux de forêt. Toute connexion établie tend à être superficielle, décontextualisée et normalisée. En revanche, diverses personnalités publiques ont incorporé les feux de forêt dans des narrations englobant l’idée de crise climatique, offrant ainsi une perspective plus intéressante, voire provocatrice.
Evaluation Of Antioxidant, Antidiabetic, Anti-Inflammatory And Anticancer Activities Of Delonix Regia Flower Extracts
Authors: Benoite. T  , Nora Vigasini K
Published: November 2021

Non-communicable diseases like diabetes and cancer are the major cause of death worldwide. Various drugs are used for the treatment of these diseases. However, they cause lots of side effects. There is a need for alternate drugs with fewer side effects. Medicinal plants serve as a good source for alternate form of treatment. Therefore, in this study, ethanolic and aqueous extracts of D. regia flowers were evaluated for their antioxidant, antidiabetic, anti-inflammatory and cytotoxic activity to justify its use as a medicinal plant. Total phenol and flavonoid content of the extracts were measured. GC-MS analysis of the extracts were done to investigate the presence of various bioactive compounds. Antioxidant activity was assessed by radical scavenging and reduction assays. Antidiabetic activity was assessed by the ability of extracts to inhibit enzyme alpha amylase. Anti-inflammatory activity was evaluated by membrane stabilization activity. Anticancer activity against MCF-7 and A549 cell lines were measured by the MTT assay.The ethanolic extract contained more phenols (282.940.80 mgGAE/g) and flavonoids (140.912.27 mgQE/g). GC-MS analysis showed the presence of compounds belonging to fatty acids, alkanes, phenols and organic alcohols. The aqueous extract showed strong superoxide radical scavenging activity with a low IC50  of 39.35±0.74 µg/mL. The ethanolic extract showed higher ferric reducing power with an IC50  of 59.65±0.28µg/mL. Ethanolic extract was more potent in inhibiting alpha amylase with a low IC50 value of 47.14±0.6 µg/mL. Ethanolic extract also showed maximum inhibition of 88.86±0.1% against heat induced lysis of cell membrane. Both extracts affected the proliferation of MCF-7 and A549 cell lines at 160 µg/mL. The results of the present study support the use of D. regia flower as a potential  source  of  bioactive  phytochemicals  and  can  be  used  as  a  plant-based  antioxidant,  antidiabetic,  anti-inflammatory  and anticancer agent.
Active Antibiotics Production by Actinomycetes Indigenous To Saudi Arabia Soils
Authors: Fetoon M. Alkhelaiwi  , Ismet Ara  , Nadine Moubayed
Published: November 2021

Streptomyces are the most popular among the Actinomycetes groups and found in soils worldwide. They form an important part of the soil ecology within the Actinomycetales order. Streptomyces are diverse as secondary antibiotic metabolites such as Novobiocin, Amphotericin, Vancomycin, Neomycin, Gentamicin, Chloramphenicol, Tetracycline, Erythromycin and Nystatin. Thus, the current study was aimed to isolate, identify and assess the active antibiotic metabolites produced by different actinomyces sp. found in Saudi Arabian soils. Six samples were collected from desert soils of the Al Thumamah area and analyzed  using  GS-MS.  Scanning  Electron  Microscopy  was  used to  identify  the  bacterial  strains  along  with  their  antibiotic metabolites effectiveness of secondary metabolites (antibiotics) against different Gram-positive (Bacillus subtilis, Staphylococcus aureus), negative pathogens (Pseudomonas aeruginosa, Escherichia coli, Salmonella suis, and Shigella sonnei) as well as the fungal strain Candida albicans was investigated. Thirty active bacterial (F1-30) strains were isolated from the soil samples and the  strains F3, F7, F22, F30 have white, gray, pink, yellow and red colours respectively. Only ten strains (F13, F14, F15, F16, FI7, F18, F19, F20, F21, and F22) were found to have antimicrobial activity against at least one pathogen. The optimum growth environment was pH 4-10, temperature (300C), and  NaCl (7% w/v) concentration. According to our findings, the extreme desert environment of Al Thumamah from Saudi Arabia is rich in its actinobacterial population with diverse colouring groups and various physiological and biochemical properties. This shows it’s capability of generating secondary metabolite elements that could inhibit pathogenic microorganisms.
Olympia. Apuntes para la comprensión de la propaganda racista en las Olimpiadas de Berlín 1936
Authors: López García Esaú
Published: November 2021

El filme de las Olimpiadas de 1936 ha llegado a ser interpretado como un documental sin fines propagandísticos, o como un testimonio del fracaso de las teorías racistas de Hitler. Es necesario analizar esta película desde su significación profunda, es decir: hay que entender su construcción teórica, para así comprender por qué el atleta Jesse Owens tiene un papel protagónico en el trabajo de Riefenstahl y por qué los latinoamericanos apenas tienen alguna aparición. La pregunta histórica que este trabajo ambiciona responder es: ¿De qué forma Olympia asimila el esquema del aparato propagandístico propuesto por Hitler y Goebbels?