bluuebunny/crossref_metadata_2025 huggingface dataset:
The Polish Crown in relations between Prussia, Sweden and Russia in 1704–1705
Authors:   Smolensk State University, Ivonina Liudmila I.
Published: September 2024

At the beginning of the 18th century, when Europe was experiencing two wars –the
War of the Spanish Succession (1701–1714) and the Northern War (1700–1721), the
Polish-Lithuanian Commonwealth was a significant object of foreign interests of Sweden,
Prussia and Russia. The struggle for influence in Poland intensified in 1704–1705 when
the king on the Polish thronechanged. Using a systemapproach that takes the interaction
and mutual influence of two European warsinto account, the article analyzes the
relationship between Berlin, Stockholm and St. Petersburg regarding the Polish Crown.The
main attention is focused on the position of Prussia because the diplomacy of Sweden and
Russia on this issue was more definite due to mutual confrontation in the Baltic. In
1704–1705,diplomatic discussions around the Polish throne played a large role in the
further development of the military and political situation on the continent. Although
the Polish-Lithuanian Commonwealth came under Swedish dominance and received a new king,
the political dissentin Poland did not allow Charles XII to dictate his will throughout
its territory.The stability of Swedish influence in Poland and the recognition of
Stanislaw Leszczynskias the Polish king in Europe largely depended on Berlin’s position.
Stockholm persistently proposed to the king of Prussia Frederick I, who was interested
in increasing his lands at the expense of Poland, to makean alliance with him. However,
the military and diplomatic activity of Peter I in the Polish-Lithuanian Commonwealth
and the Prussia’s obligations in the War of the Spanish Succession forced Frederick I to
hesitate and negotiate both with Sweden andthe legitimate king Augustus II and the
Russian sovereign.Due to the uncertain position of Prussia, the Swedish king,invaded the
Holy Roman Empire in 1706in order to force Augustus II to abdicate the Polish throne,
thatcould lead to the unification of the Northern War and the War of the Spanish
Succession.
Sediment Transport On The River Bandon, Co. Cork, Ireland
Authors:   ,   Munster Technological University, Lomasney Laurence
Published: September 2024

This thesis analyses sediment transport on the River Bandon, Co. Cork, Ireland. Bedload transport and suspended sediment transport were monitored on the River Bandon over an extended period to determine rates of transport over varying flow conditions. A literature review of sediment properties (individual and bulk sediment), sediment transport, and numerical modelling was undertaken. A manual field sampling programme was undertaken at different locations on the River Bandon to collect bed sediment and suspended sediment for laboratory testing. This data, and data collected using an automatic water sampler and bed sediment traps also, was used to determine baseline conditions for the river. Sediment transport during high flow events and the impact of instream works (dredging) on sediment transport was then assessed to compare with baseline conditions to determine the impact on sediment transport on the river. A numerical model (HECRAS) was applied to different combinations of sediment transport functions and sorting and armouring methods to determine the combination that best represents sediment transport on the River Bandon. Baseline suspended sediment conditions yielded results for suspended sediment concentration (SSC) levels in the range 1-10mg/l at varying locations along the river. Suspended sediment concentration (SSC) levels were observed to increase to 45mg/l during trial dredging undertaken in September 2016 and in excess of 350mg/l during dredging in Bandon Town in Summer 2017. In general, SSC levels increased to between 20-45mg/l during high flow events but on occasion rose to in excess of 100mg/l and the maximum SSC observed during high flow events was in excess of 330mg/l. A hysteretic loop analysis for high flow events during the data collection phase revealed that 65% of suspended sediment was transported on the rising limb of the hydrograph. Baseline bed sediment conditions yielded results for median grain size (D50) in the range of 12- 35mm. Bed sediment was observed to move for flow rates as low as 18m3/s. Using bed sediment traps, as much as 7 tonnes of bed sediment was estimated to move during a single high flow event. Bed sediment was estimated to comprise between 2-19% of total sediment load during the high flow events analysed. A numerical model, previously calibrated for hydraulic conditions on the River Bandon, was used to determine the best combination of sediment transport function and sorting and armouring method for the river. The Meyer Peter Muller function with Wong Parker correction and the Active Layer settling method combination was found to most closely simulate the observed field data.
Investigation Of The Natural Bacteriocin Nisin And Bioengineered Nisin Derivatives For The Prevention And Control of Staphylococcus Biofilms On Medical Device Materials
Authors:   ,   Cork Institute of Technology, Kearney Leanne
Published: September 2024

Antimicrobial resistance has evolved into being one the major threats facing clinical environments worldwide. It has led to the decrease in effective prevention and treatment of pathogenic bacteria. One such bacterium is Staphylococcus epidermidis. Once considered a relatively harmless and commensal bacterium, it has recently evolved into being one the leading causes of nosocomial infections. S. epidermidis has proven harmful due to its ability to form detrimental biofilms. Biofilms are structured consortia of bacteria embedded in a self-produced polymer matrix that allows adherence to biotic or abiotic surfaces. These biofilms have played a leading role in healthcare-acquired infections with particular emphasis on patients with indwelling medical devices such as urinary and intravascular catheters, and orthopaedic devices such as hip and knee implants. Biofilms are inherently refractory to treatment with antibiotics making them difficult to eradicate, which in turn can lead to infections, malfunction and removal of the device. Medical device-related infections are a public health concern and an economic burden, for example some European countries see 1000 deaths per year and ensuing costs of 35-164 million euros per year. This study investigated the potential of the natural antimicrobial agent called nisin - a bacterially derived antimicrobial peptide which is of generally recognised as safe (GRAS) status and its bioengineered derivatives (M17Q and M21A). This study examined and answered three core questions. One, nisin A prevents and controls biofilm from occurring on plastic, stainless steel, polyvinyl chloride and polyvinyl resin biomaterials. Two, the combination of nisin A and conventional antibiotics work better at preventing and treating biofilms on plastic materials, and three, nisin derivatives showed a positive indication that they work better than nisin A wildtype in the prevention of S. epidermidis biofilms on a range of materials. The results have demonstrated the potential benefits of including nisin as a viable option in the treatment of S. epidermidis biofilms in a clinical setting.
EFFECTS OF GRADED LEVELS OF PRO-VITAMIN A CASSAVA PEEL MEAL AND PROBIOTICS ON BLOOD PROFILE CHARACTERISTICS OF WEANER PIGS
Authors: Ngodoo TORHEMEN, Lynda , Ogbonna ANI, Augustine , Kanan T ORAYAGA, , Micheal TORHEMEN,
Published: September 2024

An eight-week study was conducted to determine the effect of graded levels of pro-vitamin A cassava peel meal (PVACPM) and probiotics (Lactic Dry) on Haematological and serum biochemical indices of weaner pigs. Forty-eight male large white weaner pigs aged eight weeks with an average weight of 9 kg were allotted to eight dietary treatments of six animals per treatment in a 4x2 factorial arrangement involving four levels (0,10,20 and 30%) of PVACPM and two probiotic levels (0 and 0.25g). Each treatment was replicated three times with two pigs per replicate, housed in pens measuring 2 m x 4 m. Feed and water were supplied daily to the pigs. At the end of the experimental period, three pigs were selected for the evaluation of heamatological and serum biochemical indices using standard procedures. Results obtained revealed that varying levels of PVACPM and probiotics significantly (P<0.05) impacted on heamatological and serum biochemical indices of weaner pigs. It was concluded that 30% PVACPM with or without supplemental Lactic Dry probiotic can be used in weaner pig diets for enhanced blood constituents without any adverse effect on blood profile characteristics.
EFFECT OF CHEMICAL AND PHYSICAL MUTAGEN ON GENETIC VARIABILITY PARAMETERS OF FIELD PEA
Authors: Kamal Mervat I.
Published: September 2024

Ultraviolet radiation and acridine orange has been widely applied in agriculture for inducing genetic variability within plant species to be used in crop improvement, via induced oxidative stress in plant cell. Therefore, this study aimed to increase genetic variability in field pea (Pisum sativum L.) to choose the desired traits for crop improvement which depends on the presence of many genetic variations in the population. In this study one genotype of field pea was exposed to seven doses of physical and chemical mutagens to perform mutagenesis treatments. Over night pre-socked fresh seeds in tap water and or in 200 ppm acridine orange were exposed to different times of ultraviolet irradiation (UV) and then sown in the field. The dose of 45 minutes exposure to UV revealed the maximum mean value in root length if compared with the control. The most doses of mutagens observed significant decline in the number of nodules formed per plant, as well as induced significant increase in the concentration of chlorophyll b. High values of heritability coupled with high genetic advance as percentage of mean were obtained for plant dry weight, plant fresh weight, root length, number of nodules formed per plant, leaf area, chlorophyll a and chlorophyll b. This indicated the additive gene effect governed these traits and the selection will be effective for improving them in breeding programs. Whereas, low heritability estimates coupled with low genetic advance were obtained for the number of branches per plant, total chlorophyll, as well as carotenoids in leaves and pods, indicating that these traits were more affected by environmental factors. It is concluded that inducing genetic variations in field pea is useful in designing breeding programs either by selection or crosses.
Aufwachsen in turbulenten Zeiten. Über die Anerkennung der Bildsamkeit des Kindes und die Notwendigkeit einer pädagogischen Haltung
Authors: Ammann Kira
Published: September 2024

Ausgehend von der Herausforderung des Aufwachsens unter den Bedingungen von Unsicherheit und Orientierungslosigkeit, beginnt der Beitrag mit einigen spezifischen Ausführungen über „das“ Kind und die „Form“, in welcher Erziehung stattfindet. Daran anknüpfend folgt eine Begriffsklärung von Bildsamkeit anhand der Dreiteilung von Erziehungsbedürftigkeit, Erziehungsfähigkeit und Tatsache der Erziehung in der Tradition von Herbart, ehe ich mich dem Begriff der (pädagogischen) Haltung nähere. Ziel dieses Beitrages sind weder programmatische Lösungen noch abschließende Antworten. Vielmehr möchte die Autorin auf allfällige blinde Flecken und pädagogische Herausforderungen aufmerksam machen sowie dazu anregen, über beides nachzudenken. (DIPF/Orig.)
"[D]iejenige Freiheit der Wahl...". Vier wissenschaftsdidaktische Prinzipien für das Lehrgebiet der Didaktik
Authors: Coriand Rotraud
Published: September 2024

Der Beitrag greift die folgenden Fragen auf: Wie lehrt man Didaktik? Anders gefragt: Gibt es eine Didaktik der Lehre von Didaktik als Wissenschaft? Die Autorin stellt thesenartig vier wissenschaftsdidaktische Prinzipien allgemeindidaktischer Lehre zur Diskussion, die zurückgehen auf Herbarts Gedanken zur Bildsamkeit des Menschen. (DIPF/Orig.)
Schuldhaftes Zutun? Eine 'Ereignisbeobachtung' über den disziplinären Status Allgemeiner Erziehungswissenschaft auf der Basis bibliometrischer Analysen
Authors: Fuchs Thorsten
Published: September 2024

Der vorliegende Artikel versucht, durch die Analyse der zurückliegenden Tagung der Sektion Allgemeine Erziehungswissenschaft differenzierte Erkundungen einzuholen, die es erlauben sollen, Facetten des wissenschaftlich-disziplinären Status quo zu sondieren. Er nutzt dazu Mittel der empirischen Wissenschaftsforschung. Auf der Basis der Vorträge, die vom 8.–10. März 2023 auf der Sektionstagung der Allgemeinen Erziehungswissenschaft in Koblenz gehalten wurden, wird zu ermitteln versucht, wie die teilnehmende Scientific Community an diesen Tagen über das Thema gesprochen hat – konkreter formuliert: mit welchen Titelbegriffen sie arbeitete, welche Literatur in den Vorträgen Verwendung fand, aus welchen Jahren diese stammte und welche Autor:innen hierbei genannt wurden. (DIPF/Orig.)
Nuestra Revista Virtual Universidad Católica del Norte: 25 años comunicando el conocimiento con sentido humano
Authors: Rendón Urrea Diego Luis
Published: September 2024

Esta Revista académica científica con sello Católica del Norte cumple sus bodas de plata. Ciertamente, solo una vez se cumplen 25 años, por eso las efemérides de nuestra Revista no pasan desapercibidas, porque estamos convencidos de que ciencia que no se comunica no cumple su función social. Entre otras razones porque la publicación seriada ha sido: (i) aliada incondicional del cumplimiento misional e identidad de la Fundación Universitaria Católica del Norte; (ii) testigo de la historia y crecimiento institucionales; (iii) laboratorio de escritura reflexiva, académica-científica de nuestros estamentos docentes e investigadores; (iv) ventana de divulgación científica que ha acercado la ciencia y el conocimiento, derivado de prácticas investigativas, a investigadores, docentes y estudiantes de todo el mundo, gracias al acceso libre mediante las tecnologías de la información y las comunicaciones (TIC).
Comunicación corporativa con inteligencia artificial: Casos GAD Chone y Manta
Authors: Coveña Chica Mary Carmen , Zambrano Vélez Carmen Katerine
Published: September 2024

Este artículo tiene como objetivo analizar la integración de la inteligencia artificial (IA) en la comunicación corporativa de los Gobiernos Autónomos Descentralizados (GADS) de los Cantones Chone y Manta, Ecuador. Se utilizó una metodología mixta, con entrevistas estructuradas y análisis de contenido, enfocada en los meses mayo, junio y julio de 2023. La investigación exploró la integración de IA, y se identificaron las plataformas empleadas para la creación de contenido, evaluando la interacción con la audiencia. Se encontró que la IA se aplica en diseño gráfico, producción audiovisual y redacción, aumentando la notoriedad, optimizando el tiempo y mejorando la calidad de los contenidos. Tecnologías como Midjourney, Photoshop y Leonardo.IA son usadas para automatizar tareas, incrementando la productividad, aunque enfrentan desafíos de capacitación y adaptación. El estudio concluye que la incorporación de IA ha generado cambios significativos en la comunicación corporativa. A pesar de la baja proporción de contenido generado con IA al momento de la investigación, la interacción es prometedora. El principal desafío es equilibrar la automatización con la integridad del contenido, asegurando una comunicación ética respaldada por el factor humano.
Las redes sociales como fuente de información y exploración científica en los estudiantes universitarios
Authors: Díaz Posligua Katherin Liceth , Vélez Álava Nancy
Published: September 2024

En la era digital, las plataformas de redes sociales se han vuelto fundamentales para la comunicación y el intercambio de información, así como su uso para fines de entretenimiento, algo muy común entre los universitarios que están adaptándose a nuevas formas de búsquedas y de consumo de información. Este estudio tiene como objetivo analizar el uso de las redes sociales como fuente de información y exploración por parte de estudiantes de la Universidad San Gregorio de Portoviejo (USGP). Como parte de la metodología se realizó una encuesta a estudiantes de las diferentes áreas académicas de la USGP para examinar la frecuencia con la que utilizan plataformas como Facebook, Instagram, TikTok, X y WhatsApp para acceder a contenido científico. Además, se efectuó una revisión bibliográfica con el afán de profundizar en el análisis temático.  Los hallazgos permitieron conocer el papel en evolución de las redes sociales como parte de la formación universitaria, los mismos que brindan información sobre los beneficios y desafíos que plantean estas plataformas en la búsqueda de conocimiento académico. Se concluye que un porcentaje mayoritario de estudiantes universitarios consideran que las redes sociales no son una fuente confiable de búsqueda científica, mientras que otros indagan un poco más las mismas basándose en contenido generado por expertos o instituciones reconocidas que gozan de confiabilidad.
Estudio exploratorio y correlacional de ciberviolencia en parejas conformadas por mujeres universitarias
Authors: Villalobos-Raygoza Ariadna , Rojas-Solís José Luis , Toldos Romero María de la Paz
Published: September 2024

La ciberviolencia en el noviazgo es un problema social y de salud pública, por ello la comunidad científica ha incrementado su estudio, aunque la mayoría se ha centrado en población heterosexual y cisgénero. Debido a esto, el objetivo de la presente investigación es identificar factores de riesgo para la ciberviolencia en el noviazgo conformado por mujeres. Este trabajo hizo uso del Cyber Dating Abuse Questionnaire, la Escala de Actitudes de Rol de Género y de un cuestionario ad hoc. sobre la práctica del sexting; por lo que se realizó desde el paradigma positivista con enfoque cuantitativo para obtener los análisis de confiabilidad y normalidad, las principales medidas de tendencia central, la distribución de frecuencias por ítem y las correlaciones entre las dimensiones de los instrumentos utilizados. Entre los principales hallazgos se encontró la baja frecuencia de conductas de control y agresión directa online y una asociación significativa de estas con el sexting y las creencias sobre los mitos del amor romántico. Asimismo, se resalta la necesidad de continuar incrementando las pesquisas enfocadas en minorías sexuales para el desarrollo de programas de prevención e intervención especializados en esta comunidad.
VENTRAL HERNIAS IN BASAWESHWAR TEACHING HOSPITAL KALABURAGI: A PROSPECTIVE STUDY
Authors: Allad Anveerbhadra , Farooque Mohd Umar
Published: September 2024

Surgeons frequently deal with ventral hernias, which are dened as an extension of the abdominal viscus through the anterior abdominal wall at any
point other than the inguinal and femoral sites. Aims & Objectives: The majority of surgeons advise having ventral hernias corrected as soon as
they are found because there are not any prospective cohorts available to ascertain the natural course of untreated hernias. This research sets out to
quantify the prevalence of ventral hernias in relation to age groups, genders, risk factors, complications, and clinical characteristics. displays as
well as care. Materials and Methods: A prospective study was carried out at our tertiary care hospital from August 2022 to August 2023 (12
months). A total of 50 cases with anterior abdominal hernias—groin and posterior abdominal wall hernias excluded—were included in the study.
Data were gathered by means of an extensive clinical examination and a comprehensive history. Data entry was done in the proforma calculated,
and statistical software was used for analysis (SPSS 2015). Results: 5% of surgical admissions were related to ventral hernias. Of the ventral
hernias, paraumbilical hernias were the most common type (48%). 36% of the cases were caused by an infra-umbilical midline herniation, and 18%
of the cases were umbilical area herniations. The two main risk variables that were identied were obesity and constipation. Most aws are small
(more than 2 cm). Of the inlay mesh, 48% was xed. Conclusion: This tertiary care institution conducted a study in which fty cases of ventral
hernias were examined. In the surgical ward, ventral hernias accounted for 5% of all admissions. The ratio of males to females was 1:17, with a
mean age of 41. The average overall time spent on surgery in the sublay group was 75.4±9.23 minutes, while the onlay group's average was
63.7±10.58 minutes. It had a statistically signicant difference (p<0.05).
AN EVALUATION ON THE CONSEQUENCES OF THE INTRODUCTION OF ONLINE CLASSES AMIDST THE LOCKDOWN ON SCHOOL STUDENTS
Authors: Kapoor Agrima
Published: September 2024

Background: Although there are studies and data indicating the effects of increased usage of devices amongst children but no such data as to
quantify how many folds these effects increased when ofine classes were completely replaced by online classes which required using devices
during majority of the day. Objective: This study aims to analyze the effects of online classes started during lockdown on the health of school
students. Methodology: The study was a prospective and cross-sectional study and was conducted in two schools of district Kangra, Himachal
Pradesh - Aadhunik Public School Dharamshala and Achiever's hub public school Dharamshala. These two schools had a student capacity of
1200+ each. A questionnaire was created on a virtual platform i.e., Google Forms. The questionnaire consisted of 3 parts- consent, prole of
students and Health problems faced by the students. The school administration of both the schools were approached and were explained about the
study. They gave their approval and helped circulate the questionnaire amongst their students via a digital messaging platform. The only
prerequisite to ll the form was to have a Gmail id which was available for all the students as the schools which were selected for study had
conducted online classes through google meet and that also required Gmail id. The link so shared could be opened on a handheld device and didn't
require any app. Conclusion: Out of 159 participants 22.64% participants wore spectacles and 89.94% participants had no medical complaints
prior to the start of online classes. 62.89% starting facing issues concentrating ,43.40% students complained of frequent headache and 55.35%
students complained of increase in irritability in their behavior as the classes progressed. 41.51% students reported weight gain, 61.01% reported
decreased interest in studies and 54.72% students complained about being more tired from online classes compared to the same duration ofine
classes. 43.40% experienced episodes of disturbed sleep,11.95% were prescribed spectacles and 64.78% complained about experiencing neck pain
after the commencement of online classes.
DUODENECTOMY WITH PANCREATICOJEJUNOSTOMY FOR MULTIPLE CARCINOIDS OF DUODENUM: A CASE REPORT
Authors: Afonso Bossuet , Kalangutkar Amit , Juwarkar Sanjeev , R. Lawande Prashant
Published: September 2024

Duodenal carcinoid is a rare tumor with no specic guidelines for management and is traditionally managed by a pancreaticoduodenectomy. The
main issue with this procedure is the high morbidity even in expert hands and a perioperative mortality rate of 1-2%. In this case report, we describe
a case of multiple duodenal carcinoids managed without a formal pancreaticoduodenectomy, who underwent a subtotal duodenectomy with
reimplantation of ampulla of Vater in the jejunum.
Epidemiological Study of Malaria in the Neonatal Period Reference Hospital of Sibiti Department of Lekoumou Republic of Coongo Brazzaville
Authors: Aranda N. , Gayela B. , Nguebili R.
Published: September 2024

Malaria remains a rare condition in newborns, even in endemic areas, meaning that its search is not too systematic at this age. Our study aims to describe the profile of malaria during the neonatal period. The retrospective descriptive study focused on the files of newborns hospitalized from 12/01/2023 to 06/1/2024, in the pediatrics and neonatology department of the Sibiti reference hospital in the department of lekoumou in Congo Brazzaville. Inclusion criteria were fever, isolated or not, and a positive thick film/blood smear (GE/FS). The exclusion criterion was the positivity of the biological infection assessment. The parameters studied took into account epidemiology, clinical, biology and therapeutics. Results: The prevalence of neonatal malaria was 0.05% (22/398) according to our study. Apart from fever which was an inclusion criterion, pallor was the dominant symptom. Three of our patients had a history of blood transfusion and 2 of these had severe postnatal malaria, with increased parasitemia.
Pituitary Adenoma Presenting with Acute History of Severe Headache, Hypotension, and Ptosis
Authors: Elgonaid Dr. Rahaf Wael , Chandio Dr. Rida Rauf
Published: September 2024

A female patient in her seventies presented with acute onset of severe headache and third nerve palsy. Initial evaluation showed ptosis of the left eyelid, dilated left pupil, and restricted eye movements. MRI confirmed a pituitary macroadenoma. The patient was managed with hydrocortisone and conservative measures but experienced significant complications during treatment. This case underscores the diagnostic and management challenges of pituitary adenomas, emphasizing a multidisciplinary approach.
Mayer-Rokitansky-Küster-Hauser Syndrome: A Case Report
Authors: Taoufiki S. , Hamdane J. , Ahmmana C. , Zouita I. , Basraoui D. , Jalal H.
Published: September 2024

Mayer-Rokitansky-Küster-Hauser syndrome is a rare congenital anomaly affecting the development of the female reproductive organs. Its etiology remains undetermined, but genetic and environmental factors may play a role in its development. It comprises two types, type I isolated and type II associated with renal, vertebral or cardiac anomalies. MRI is the examination of choice to confirm the diagnosis. In the light of a Mayer-Rokitansky-Küster-Hauser observation in a 26-year-old woman who consulted us for primary amenorrhea with pelvic pain. The purpose of this case report is to raise the possibility of a diagnosis of primary amenorrhea in a young woman with normal sexual characteristics.
Personalized Feedback in Survey: Theories and Applications
Authors:   The Korean Association Of Personnel Administration, Mah Sunghyuck , Kim Jayoung , Lee Yoowoo , Lee Donghwan
Published: September 2024

This study discusses the theoretical background and practical applications of providing personalized feedback in surveys, a research methodology widely used in the social sciences, including business management and organizational behavior. The major goal is to evaluate the utility of individualized feedback from a methodological standpoint, as opposed to typical monitoring and improvement goals in medical and educational settings, and to present theoretical findings and applications. Given the growing public and media interest in quantitative self-assessment and knowledge, providing individualized feedback in surveys could be a significant incentive to encourage participants to reply honestly and with care. To investigate this possibility, this study first examines theories, including general motivation, specific survey response theories, and past research findings. It then empirically investigates the effect of personalized feedback on response quality (i.e., the degree of careless responding) in the context of organizational behavior research. Finally, this study shares methods for utilizing personalized feedback within the research context and practical HR settings, including the creation and distribution processes using Excel. Furthermore, this study aims to pique academic and practitioner interest in a synergistic paradigm that not only confirms research hypotheses through surveys but also increases participants’ interest and selfunderstanding, taking into account the benefits to participants as well.
Orbital floor reconstruction based on 3d printed model – case report
Authors: Pławecki Piotr , Jędrusik-Pawłowska Magdalena , Rolek Agnieszka , Cieślik-Bielecka Agata
Published: September 2024

Orbital fractures, constituting 10-25% of facial traumas, result from diverse mechanisms such as traffic accidents and assaults. These fractures present with characteristic symptoms like edema, diplopia, and infraorbital paraesthesia. Timely diagnosis and surgical intervention are paramount to mitigate long-term complications. Recent advancements in materials science and surgical methodologies have ushered in innovative approaches including 3D printing and computer-aided design implants. This article details a case study of successful reconstructive orbital surgery in a patient following a traumatic incident where a car accident caused extensive facial fractures. Leveraging 3D printing technology, a precisely tailored titanium mesh aided in the meticulous restoration of the orbital floor. During surgery, entrapped soft tissues were released, and the zygomatic-maxillary complex was carefully repositioned. Postoperative evaluation revealed promising outcomes, affirming the efficacy of contemporary surgical strategies. This case highlights the evolving role of 3D printing in enhancing the accuracy, cost-effectiveness, and accessibility of orbital reconstruction procedures, demonstrating its potential for broader clinical applications.
Complex mechanism of brugada phenocopy: moderate hyponatremia and right ventricular compression by liver metastatic tumor – case report
Authors: Elikowski Waldemar , Strzelecka Anna , Fertała Natalia , Zawodna-Marszałek Magdalena , Żytkiewicz Marcin
Published: September 2024

Brugada phenocopy (BrP) occurs in various clinical conditions and manifests as a Brugada-like ECG pattern with coved (type 1) or saddle-back (type 2) ST-segment elevation in the right precordial leads. Unlike Brugada syndrome (BrS), which is an inherited channelopathy, BrP is not associated with an increased risk of malignant arrhythmia. BrP has been reported in severe metabolic disturbances (significant hyponatremia, hypokalemia or hyperkalemia), mechanical heart compression, coronary artery disease, pulmonary embolism and myocarditis/pericarditis. The authors described a case of a 69-year-old female whose Brugada-like ECG was atypically associated with only moderate hyponatremia (127 mmol/l). She was admitted due to a skin and subcutaneous tissue infection of the left shank and coexistent urinary tract infection (without a fever). She had the history of advanced melanoma with multiple liver metastases. Her cardiac history was negative, especially the patient has never suffered from ventricular arrhythmias. ECG on admission showed saddle-back ST-segment elevation in the right precordial leads; however, the patient did not report any chest pain. Troponin I level and left ventricular function in echocardiography were normal while regional longitudinal strain in RV apex was decreased and showed post-systolic shortening. The substernal view revealed compression of the right ventricle (RV) by liver metastatic tumor. ECG changes disappeared quickly during natrium chloride supplementation and did not recur during hospitalization. This case illustrates that even moderate hyponatremia may be a reversible cause of BrP when other predisposing conditions (e.g. heart compression by tumor) coexist.
Modulation of immune responses in the liver: The role of curcumin in balancing between health and disease
Authors: Singh Prashant Anilkumar , Mukherjee Sitabja , Gandhi Puneet , Kar Santosh
Published: September 2024

The human liver, traditionally viewed as a metabolic and detoxifying organ, is now being acknowledged for its complex immunological activities involving diverse resident immune cell populations and non-hematopoietic cells. Even in the absence of disease, the liver actively engages in immune surveillance and regulatory processes to support metabolic functions and tissue remodeling, influenced by continuous exposure to dietary and microbial elements. However, maintaining a delicate balance within this dynamic microenvironment is crucial, as uncontrolled inflammation can result in pathological conditions. Effective immune activation is essential for responding to challenges such as pathogens or tissue damage, while mechanisms for resolving inflammation are necessary to maintain liver homeostasis. This review examines the diverse roles of hepatic inflammatory mechanisms in both normal and pathological liver conditions, where dysregulation contributes to chronic inflammation and diseases. A key focus of this discussion is the potential therapeutic role of curcumin, the primary curcuminoid found in turmeric. Curcumin is well known for its potent antioxidant and anti-inflammatory properties and has shown the ability to modulate various signaling pathways. Notably, curcumin acts by suppressing nuclear factor kappa B (NF-κB), a crucial player in the inflammatory cascade. NF-κB not only triggers inflammation but also influences cell survival, proliferation, invasion, and angiogenesis. Drawing from existing literature, we emphasize curcumin’s ability to scavenge free radicals, reduce lipid peroxidation, and target NF-κB-dependent pathways. By elucidating the evolving comprehension of inflammation’s role in maintaining liver balance, we suggest that curcumin represents a promising approach for treating chronic liver inflammation, thereby preventing fibrosis and related ailments. This thorough analysis highlights the potential of curcumin in modulating immune regulatory pathways specific to the liver, providing valuable insights into its use as a targeted therapeutic intervention against chronic liver inflammation that results in fibrosis.
3D-printed scaffold of dopamine methacrylate oligomer grafted on PEGDMA incorporated with collagen hydrolysate for engineering cartilage tissue
Authors: Pasanaphong Kitipong , Suksuwan Acharee , Srikaew Narongrit , Hemstapat Ruedee , Tawonsawatruk Tulyapruek , Wangtueai Sutee , Khamthong Nanthaphong , Boonyagul Sani , Wongsirichot Phavit , Tanadchangsaeng Nuttapol
Published: September 2024

This study demonstrated the synthesis and characterization of dopamine methacrylate (DMA), oligomers of dopamine methacrylate (ODMA), and their integration with polyethylene glycol dimethacrylate (PEGDMA) to enhance 3D-printing scaffold fabrication for tissue engineering, using digital light processing (DLP) technology. The results confirm the successful synthesis of DMA, as evidenced by NMR and FTIR analysis and its subsequent conversion to ODMA. The obtained ODMA was then combined with PEGDMA (1.25-10 %w/v of ODMA) to optimize scaffold printability. The morphological characteristics of the ODMA/PEGDMA scaffolds were assessed via scanning electron microscopy (SEM). Furthermore, using FTIR and DSC, the chemical stability and biological compatibility of collagen hydrolysate (CH) derived from tuna tendon were studied and compared after the sterilization method. An in vitro fibroblast viability test was conducted using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay to assess the biocompatibility of the CH with cells. Sterilization methods did not adversely affect the chemical compositions of CH, maintaining its compatibility with fibroblast cells. Subsequently, the ODMA/PEGDMA/CH composite scaffolds were fabricated with digital light processing (DLP) 3D printer and their efficacy in supporting chondrocyte viability and proliferation were examined at 24, 48, and 72 hours using PrestoBlue® assay. Mixing ODMA with PEGDMA significantly enhanced the printability of the scaffolds. Our tri-component 3D-printed scaffolds significantly enhanced human cartilage stem/progenitor cells (CSPCs) viability and proliferation compared to the 24-well culture plate. These scaffolds excel not only in mechanical properties, which are crucial for bearing physiological loads but also in biological properties that promote cell growth and proliferation. This dual enhancement underscores their superior performance and positions them as frontrunners in the development of advanced solutions for cartilage engineering, potentially revolutionizing medical treatments.
Factors Driving Artificial Intelligence Adoption in South Africa's Financial Services Sector
Authors: Hassan Adewale Samuel
Published: September 2024

Incorporating digital technologies, particularly artificial intelligence, into financial services operations is imperative for achieving critical sustainable development goals (SDGs) through digital financial inclusion. This paper examines the drivers behind AI adoption in South Africa's financial services landscape, given its highly advanced financial sector and rapidly evolving digitisation trends. Drawing on the Technological-Organizational-Environmental (TOE) framework, the study investigates the factors influencing AI adoption through a comprehensive analysis of existing literature, a survey of financial services professionals and binary logistic regression. The results of binary logistic regression indicated that technological, organisational and environmental improvements significantly enhance the likelihood of AI adoption in South Africa's financial services sector. Specifically, access to technological infrastructure, organisational leadership support, and regulatory clarity emerge as key determinants of AI adoption. Overall, this study underscores the need for companies in the financial sector to encourage a culture that welcomes innovation and the integration of AI technology, as well as the need for policymakers to develop comprehensive and unambiguous legislative frameworks that control AI use in financial services.
 
Received: 13 March 2024 / Accepted: 31 August 2024 / Published: 05 September 2024
FOREIGN INVESTMENT: CONVENIENCE ADN LEGAL PROTECTION FOR INVERSTOR
Authors: Novendra Fakhri Muhammad
Published: September 2024

President Joko Widodo's administration has made every effort to increase the value of foreign direct investment, data of foreign direct investment’s growth has also shown a significant increase, but has foreign direct investment that is predicted to be able to become the backbone of Indonesia in breaking away from becoming a developing country has been properly accommodated? Foreign direct investment requires legal certainty which will spread to all parts of the foreign direct investment process. Therefore, legal certainty is one of the main factors for a country to attract foreign direct investment capital into the a country. There is a need for broader and comprehensive legal certainty to ensure that foreign investors can be guaranteed from a legal perspective to do business and build Indonesia together. Not only legal certainty in the investment sector, but also other domestic legal certainty related to the investment climate, one of the most important is environmental law relating to sustainable development. This article will discuss the basics of foreign direct investment, the importance of foreign direct investment, factors attracting foreign direct investment, President Joko Widodo's new policies and regulations on foreign direct investment, current data of the realization of foreign direct investment and investor’s consideration to ensure themselves and their initial funds of their investment is safe as long as they invest in Indonesia. Keywords:  Foreign Direct Investment, economy policies, legal certainty
Manajemen Tenaga Kependidikan di SMP IT ULIL ALBAB Pematang Siantar
Authors: Uchrowi Nasution Fairuza Nur , Darmansyah Tengku
Published: September 2024

This study discusses the application of Education Personnel Management in SMP Islam Terpadu Ulil Albab Pematang Siantar. The research method used is quantitative research. Researchers process and analyze the data that has been obtained in the field by using Miles and Huberman analysis models and testing the validity of the data used by researchers, namely triangulation of sources, methods, and time. The results of the research that researchers have been able to in the field show that, the implementation of the management of educational personnel in SMP it Ulil Albab Pematang Siantar has been well applied in accordance with the theory of planning and analysis, then hold recruitment and selection properly, implement the introduction, placement, and dismissal in accordance with the procedures, conduct training and development, provision of compensation or Remuneration, and termination of the appropriate relationship between theory and application applied in SMP IT Ulil Albab Pematang Siantar, The performance of employees at SMP it Ulil Albab Pematang Siantar has been very good. as evidenced by the increasing number of applicants for new prospective students in each new school year and the achievements achieved by their students prove that teachers and employees at SMP it Ulil Albab Pematang Siantar have a good performance., The supporting factors for the implementation of the implementation of Education Personnel Management in SMP it Ulil Albab Pematang Siantar run successfully because employees get good attention such as the fulfillment of facilities and infrastructure to support the teaching and learning process to run effectively and efficiently, the fulfillment of employee rights, and the fulfillment of the welfare of employees. There is no considerable obstacle in the implementation of Education Personnel Management in SMP it Ulil Albab Pematang Siantar.
Pengaruh Citra Merek, Kualitas Produk, Sertifikat Halal Dan Keputusan Pembelian Terhadap Permintaan Produk Hand Body Lotion Citra (Studi Kasus : Pada Masyarakat Kelurahan Dwikora, Kecamatan Medan Helvetia)
Authors: Aprillia Wina , Harmain Hendra , Jannah Nurul
Published: September 2024

This study aims to determine the effect of brand image, product quality, halal certificates, and purchasing decisions on product demand. This research was conducted using a quantitative approach. The population in this study amounted to 300 with a sample of 75. The sampling method was simple random sampling technique. This study uses primary data using multiple linear regression data analysis using SPSS 15. Based on the results of the first hypothesis test, it is known that the significant value of brand image is 0.085 (sig > 0.05) with a t-count value of 1.750 <1.994 (t-count < t-table). The second hypothesis test showed a significant product quality of 0.825 (sig > 0.05) with a t-count value of 0.222 <1.994 (t-count < t-table), the third hypothesis test showed a significant halal certificate of 0.486 (sig > 0.05) with a t-count -0.700 < 1.994 (t-count < t-table), the fourth hypothesis test showed a significant 0.000 (sig < 0.05) with a t-count value of 4.368 > 1.994 (t-count > t-table). Based on the results of the fifth hypothesis test, it is known that the significant value is 0.000 (sig <0.05) with an f-count value of 22.193 > f-table 2.503. The results of this study indicate that Brand Image, Product Quality, Halal Certificate and Purchasing Decision simultaneously influence product demand.
Pengaruh Inflasi, Nilai Tukar, Harga Minyak Dunia Dan Harga Emas Dunia Terhadap Indeks Saham Syariah Indonesia
Authors: Hasibuan Fauzan Fahmi , Soemitra Andri , Harahap Rahmat Daim
Published: September 2024

This study aims to examine inflation, exchange rates, world oil prices and world gold prices against the Indonesian Sharia Stock Index for the 2017-2021 period. The method used in this study is the historical method which is distributive causal in nature, meaning that research is conducted to analyze a past situation and indicate the direction of the relationship between variables. The data collection technique used is documentation taken through online data files from the internet. The data used in this study is secondary data in which the data is obtained indirectly from statistical data and published data. Data analysis used multiple linear regression analysis. The results of the study show that the variables Inflation, Exchange Rates, World Oil Prices, World Gold Prices simultaneously have an influence on the Indonesian Sharia Stock Index. It can be seen that the calculated F value (97.929) > F table (2.54) and a significance value of 0.000 <0.05. So it can be concluded that Inflation, Exchange Rates, World Oil Prices and World Gold Prices simultaneously (together) have a significant effect on the Indonesian Sharia Stock Index. In addition, from the results of the determination test, the calculated R2 coefficient (determination coefficient) is 0.855 (85.5%).
Analisis Risiko Usaha Peternakan Ayam Broiler Dengan Pola Kemitraan Di Desa Sampean Kecamatan Sungai Kanan Kabupaten Labuhanbatu Selatan Provinsi Sumatera Utara
Authors: Tanjung Rika Putri Harapan , Ramadhani Sri , Aslami Nuri
Published: September 2024

This study aims to analyze the risk of broiler chicken farming with a partnership pattern in Sampean Village, Sungai Kanan District, South Labuhanbatu regency, North Sumatra province. This study uses descriptive qualitative methods with data collection techniques, namely observation, interview, and documentation. The results showed that in the cultivation of broiler chickens is inseparable from the existence of business risks, the most common risks are production risks and price risks. Production risks faced by farmers in Sampean Village are the risk of dead chickens, stressed chickens, chickens exposed to disease, and price or market risks. The strategy in overcoming the risk is the identification of risks by tracing the risks contained in broiler chicken farming, evaluation / risk analysis by evaluating the risks after knowing what are the sources of risks faced by farmers such as the causes of chicken deaths, controlling risks by designing the best and economical way to reduce the risk of chicken deaths by providing drugs or vaccines provided by partner companies and herbal medicines formulated by farmers themselves. However, broiler chicken farmers in Sampean village have obstacles in overcoming their business risks, namely the lack of competence of farmers in overcoming the risks that exist in broiler chicken farming businesses.
Analisis Efektivitas Incentive Compatible Constraints Dalam Pembiayaan Mudharabah (Studi Pada PT. Bank Syariah Indonesia KC Medan Ahmad Yani)
Authors: Sulvira Akbar Saragih Ahmad Reza
Published: September 2024

This study aims to determine the background of the application to analyze the effectiveness of Incentive Compatible Constraints in mudharabah financing at Bank Syariah Indonesia KC Medan Ahmad Yani. Effectiveness comes from the word effective which means Effect, influence that can bring results. Effectiveness is a description of the level of success in achieving the goals set.. Data collection methods using interviews, observation and documentation. While the data analysis techniques used are descriptive qualitative analysis. The results showed that the implementation of incentive compatible constraints in mudharabah financing at Bank Syariah Indonesia branch office Medan Ahmad Yani was allowed because the implementation of incentive compatible constraints was proven to prevent losses incurred by customers who were not trustworthy. ICC implementation is allowed because the Bank adheres to the principle of prudence and mutual assistance in accordance with the Qur'an surah Al-Maidah Verse 2 and Al-Hujurat verse 6.
Analisis Indeks Pembangunan Manusia Yang Berpengaruh Terhadap Tingkat Kemiskinan Di Provinsi Banten
Authors: Desmawan Deris , Valentino Dikie , Kusuma Ferdiyana Indra , M M. Fajar , Ardani Novi , Sumarni Pipin
Published: September 2024

The Human Development Index (HDI) and poverty level are two important aspects of economic development that are interrelated. HDI is a benchmark used to assess the level of welfare of the population of a region, while the poverty rate indicates the number of individuals living below the poverty line. The purpose of this research is to examine the impact of the Human Development Index on the poverty rate in Banten Province.