bluuebunny/crossref_metadata_2025 huggingface dataset:
Nanoscale materials at work: Mapping emerging applications in energy, medicine, and beyond
Authors: Hughes kevin J. , Ganesan Magesh , Tenchov Rumiana , Iyer Kavita A. , Ralhan Krittika , Diaz Leilani Lotti , Bird Robert E. , Ivanov Julian , Zhou Qiongqiong
Published: April 2024

Since their inception in the early 1960s, the use of nanoscale materials has progressed in leaps and bounds, and their role in diverse fields ranging from human health to energy is undeniable. In this report, we utilize the CAS Content Collection, a vast repository of scientific information extracted from journal and patent publications, to identify emerging topics in this field. This involves understanding trends, such as the growth of certain topics over time, as well as establishing relationships between emerging topics. We achieved this by using a host of strategies including a quantitative natural language processing (NLP) approach to identify 279 emerging topics and sub-topics across three major categories – materials, applications, and properties – by surveying roughly 3 million publications in the nanoscience landscape. This wealth of information has been condensed into several conceptual mind maps and other graphs that provide metrics related to the growth of identified emerging concepts, group them into hierarchical classes, and explore the connections between them. We delved deeper into four major emerging applications of nanoscale materials – drug delivery, sensors, energy, and catalysis – to provide a more comprehensive and detailed picture of the use of nanotechnology in these fields. In addition, we leveraged the CAS registry, consisting of over 250 million substances, to determine and discover substances across varied classes (such as polymers, elements, organic/inorganic molecules) and how they are utilized in the 4 major applications. Our extensive analysis taking advantage of an NLP-based approach along with robust CAS indexing provides valuable insights in the field that we hope can help to inform and drive future research efforts.
Mononuclear Palladium(I) Aryl Complexes Performs Cross-Coupling Reactions with Organic Halides
Authors: Xia Tianqi , Long Linhong , Leng Xuebing , Chen Hui , Deng Liang
Published: April 2024

Mononuclear Pd(I) species represent the least understood Pd intermediates in Pd-catalyzed reactions and isolable complexes of the type are exceedingly rare. Herein, we report the synthesis and characterization of mononuclear Pd(I) complexes bear-ing aryl ligands, namely [(IPr)Pd(ArTrip-R-p)] (ArTrip-R-p = 4-R-2,6-bis(2’,4’,6’-triisopropylphenyl)phenyl, R = H, CF3), as well as their reactions with organic halides. The Pd(I) aryl complexes were prepared from the reactions of [(IPr)PdCl2]2 with the corresponding aryl lithium salts and have been characterized by various spectroscopic methods. EPR spectroscopy and calculation studies suggest their Pd(I) nature. Reactivity studies using [(IPr)Pd(ArTrip-CF3-p)] as the representative revealed the capability of the Pd(I) aryl complex in activating the carbon-halogen bonds of organic iodide and benzyl halides. In the reactions with para-substituted benzyl bromides, C(aryl)-C(benzyl) cross-coupling products are formed in moderate to good yields. Kinetic studies, radical trapping experiments, and theoretical calculations point out that the cross-coupling products are likely formed from the sequential steps of stepwise oxidative addition reaction of Pd(I) aryl complex with benzyl bromide involving Pd(II) intermediate followed by reductive elimination reactions of the resulting Pd(III) intermediates.
Denoising Drug Discovery Data for Improved ADMET Property Prediction
Authors: Adrian Matthew , Chung Yunsie , Cheng Alan
Published: April 2024

Predicting ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties of small molecules is a key task in drug discovery. A major challenge in building better ADMET models is the experimental error inherent in the data. Furthermore, ADMET predictors are typically regression tasks due to the continuous nature of the data. This makes it difficult to apply existing methods as most focus on classification tasks. Here, we develop denoising schemes based on deep learning to address this. We find that the training error can be used to identify the noise in regression tasks while ensemble-based and forgotten event-based metrics fail to detect the noise. The most significant performance increase occurs when the original model is finetuned with the denoised data using training error as the noise detection metric. Our method has the ability to improve models with medium noise and does not degrade the performance of models with noise outside this range. To our knowledge, our denoising scheme is the first to improve model performance for ADMET data and has implications for improving models for experimental assay data in general.
Pengaruh literasi keuangan, sistem informasi akuntansi, adopsi it dan green innovation performance terhadap kinerja keuangan umkm di Jawa Tengah
Authors: Nareswari Ade Heaven , Winarsih Winarsih
Published: April 2024

Penelitian ini bertujuan untuk menguji pengaruh literasi keuangan, sistem informasi akuntansi, adopsi IT, dan Green Innovation Performance terhadap Kinerja Keuangan UMKM. Meningkatkan kinerja keuangan UMKM sangatlah penting dikarenakan UMKM memiliki kontribusi yang cukup besar untuk perekonomian Indonesia salah satunya didaerah Pemalang. Peningkatan informasi keuangan dan teknologi keuangan sangat dibutuhkan oleh UMKM. Literasi keuangan, sistem informasi akuntansi, adopsi IT serta Green Innovation Performance (GIP) diprediksi menjadi faktor yang mempengaruhi peningkatan Kinerja Keuangan UMKM. Dengan pemahaman literasi keuangan yang baik, pelaku UMKM diharapkan dapat membuat keputusan keuangan yang tepat sehingga meningkatkan kinerja keuangan UMKM. Sistem Informasi Akuntansi yang baik menghasilkan laporan keuangan yang bermanfaat. Pengadopsian IT berguna meningkatkan transformasi bisnis dan efisiensi sehingga dapat memperluas jaringan pemasaran UMKM. Serta, Green Innovation Performance yang baik berdampak kepada meningkatnya CSR dengan tujuan mengurangi dampak lingkungan yang dihasilkan oleh UMKM. Responden pada penelitian ini adalah 400 UMKM yang terdapat didaerah Pemalang. Penelitian ini menggunakan metode purposive sampling. Data penelitian ini menggunakan data primer hasil dari kuesioner. Metode analisis yang digunakan adalah analisis regresi berganda dengan aplikasi SPSS versi 25.

This research aims to examine the impact of financial literacy, accounting information systems, IT adoption, and Green Innovation Performance on the financial performance of MSMEs. Improving MSME financial performance is crucial because MSMEs contribute significantly to the Indonesian economy, especially in the Pemalang region. MSMEs require enhanced financial information and financial technology. Financial literacy, accounting information systems, IT adoption, and Green Innovation Performance (GIP) are predicted to influence the improvement of MSME financial performance. With a good understanding of financial literacy, MSME operators are expected to make sound financial decisions, thereby improving MSME financial performance. A robust accounting information system yields useful financial reports. The adoption of IT enhances business transformation and efficiency, potentially expanding the marketing network of MSMEs. Additionally, strong Green Innovation Performance positively impacts CSR initiatives aimed at reducing the environmental impact caused by MSMEs. The respondents in this study include 400 MSMEs in the Pemalang region. The research employs a purposive sampling method. Primary data were collected through questionnaires. The analysis method used is multiple regression analysis using SPSS version 25.
The effect of jack bean (Canavalia ensiformis L.) starch modification annealingheat moisture treatment on physical and chemical characteristics of biscuit
Authors: Ariyantoro A.R. , Affandi D.R. , Rahmah A.S.
Published: April 2024

Biscuits are one of the food products that are in great demand by the people of Indonesia
with a consumption growth rate of 4.25% from 2016 to 2020. Biscuits have the
characteristics of low moisture content so they have a long shelf life. In this study,
innovation was carried out on the main raw material of biscuits using the substitution of
jack bean starch (Canavalia ensiformis L.) modified by annealing-heat moisture treatment
(HMT). This study aimed to determine the effect of HMT and annealing-HMT on the
physical and chemical characteristics of biscuits and to determine the best biscuit
formulation. The design used in this study was completely randomized design (CRD) with
one factor in the combination of modified starch and biscuit formula, namely control
(100% flour), native starch (100%), native starch: wheat (50:50), native starch (100%),
HMT modified starch: wheat (50:50), HMT modified starch (100%), annealing HMT
modified starch: flour (50:50), and annealing HMT modified starch (100%). Based on the
research, it was found that the substitution of wheat flour using annealing HMT
modification starch affects brighter color, lower hardness and fracture strength, lower
moisture content, ash content, fat content, and protein content, as well as increment in
carbohydrate content. The best formula was determined based on multiple attributes,
namely the F7 formula with 100% annealing HMT starch modification.
Imaginary Synthetic Realms- Fostering digital creativity through urban connectivity
Authors:   , Yu Fiona
Published: April 2024

The study aims to envision how the future generation experiences architecture through the intersection of technology and place. Drawing on the theoretical framework of the creative class as pioneers of cultural and creative innovation, this research focuses on urban space, technology and people within large metropolitan cities. The research mainly explores youth creativity by introducing immersive digital amenities into urban environments within a mixed-reality city. The objective is to delve into digital architecture, examining its role in urban spaces for fostering exponential creative expression. Expanding its scope from Wellington, New Zealand, to dynamic cities in Southeast/East Asia, including Ho Chi Minh City, Vietnam, and Seoul, Korea, this study employs a research-through-design methodology. The emphasis lies on iterative architectural development using models, images, and animations. Visual media, spanning static states, animation, sound, and movement, depict the creative communities emerging from digital ethnography. The popular interaction of hand-held interaction technologies are leveraged as tools to explore opportunities for situating public urban design concepts within digital communication.

This research seeks to foster engaging architectural experiences by recognising the built environment as a canvas for creative connections. It was limited to one creative expression created as basis to the conceptual engagement. The results examines an ultimate goal to facilitate creative architectural engagement by incorporating mixed reality components. Providing a significant innovative lens for the youth to interact with and contribute to their urban surroundings.
Inclusive Education in the Context of Ethnocultural Diversity: Understanding the Process of Exclusion in Order to Act in the School – A Secondary Publication
Authors: Magnan Marie-Odile , Gosselin-Gagné Justine , Audet Geneviève , Conus Xavier
Published: April 2024

This issue reveals that the implementation of inclusive education is an unfinished challenge, both within the system and for individual self-improvement. This process of changing practices, by continually questioning the school’s responsibility for the (re)production of inequalities, exclusion, and unequal social relations, is riddled with obstacles, unpredictable situations, and strong emotions. In particular, the researchers point out that many systemic mechanisms of school culture contribute to replicating and reifying hierarchical school experiences and exacerbating processes of institutional discrimination against immigrant backgrounds and/or racialized students. The empirical research presented also highlights the deficit thinking of school staff toward immigrant students and their parents. The results show that staff tend to use linguistic and cultural gaps between students and the school system to explain academic failure. Be that as it may, the researchers as well as the school actors and students interviewed in this issue suggest fertile ways to improve inclusion in the school context, stressing the importance of giving voice to the various actors to move toward institutional transformation.
Mental health of medical students' during COVID-19 pandemic
Authors: Fedotova Zoya
Published: April 2024

Introduction. The article focuses on the importance of studying the mental health of medical students. It specifically compares the mental well-being of domestic and foreign students, highlighting cultural and educational differences that impact their mental health. Given the COVID-19 pandemic, stress and anxiety levels among students, especially in the medical field, have increased, making this study highly relevant. The article proposes the development of a psychocorrection program to maintain and improve mental health using proven approaches and techniques adapted to medical education and student life. This program can be easily integrated into the educational process to effectively reduce psychological stress, prevent serious mental disorders and improve the mental health of students. Materials and methods. 185 higher education students were surveyed, including: 94 domestic students (main group) and 91 foreign students (comparison group). Both groups were from the Bogomolets National Medical University. The following methods were used in the study: ADNM-20, HADS, CSE, FPI, NSI, SF-36, CD-RISC, DERS. The following methods of statistical data processing were used in your work: descriptive statistics to summarize demographic and other basic characteristics of the groups, such as mean values (μ ± SD), percentages, and number of participants in each group. t-test for independent samples to compare the mean values between two groups of students (domestic and foreign) on different psychological scales. The Mann-Whitney U-test was also used to test for statistical differences between two independent groups when the data distribution did not follow a normal pattern. Pearson's correlation coefficient to analyze the relationships between different psychological and demographic variables in domestic and international students. Effect size analysis to assess the practical significance of the identified statistical differences between the groups. We have additionally performed a regression analysis. Results. Findings from recent research have shown that international students experience notably higher levels of stress, anxiety, and adaptation difficulties in comparison to their domestic counterparts. It is widely believed that these challenges are due, in large part, to the additional pressure of cultural adaptation and language barriers. To tackle this issue, a psychocorrection program has been proposed, with a specific focus on medical students. The program aims to use cognitive-behavioural interventions to enhance resilience and emotional regulation, with the ultimate goal of mitigating psychological distress and improving overall mental well-being.
In-situ and laboratory characterisation of stiff and dense geomaterials for driven pile analysis and design
Authors: Liu Tingfa , Vinck Ken , Ushev Emil , Jardine Richard
Published: April 2024

Integrated field and laboratory characterisation of geomaterial behaviour is critical to foundation analysis and design for a wide range of offshore and onshore infrastructure. Challenges include the need for high-quality sampling, addressing natural and induced micro-to-macro structures, and applying soil and stress states that represent both in-situ and in-service conditions. This paper draws on the Authors’ recent research with stiff glacial till, dense marine sand and low-to-medium density chalk, and focuses particularly on these geomaterials’ mechanical behaviour, from small strains to failure, their anisotropy and response to cyclic loading. It considers a range of in-situ techniques as well as highly instrumented monotonic and cyclic stress-path triaxial experiments and hollow cylinder apparatus tests. The outcomes are shown to have important implications for the analysis of large driven piles under monotonic-and-cyclic, axial-and-lateral loading, and the development of practical design methods. Also highlighted are the needs for approaches that integrate field observations, advanced sampling and laboratory testing, numerical and theoretical modelling.
Impact of Projects with Future Potential on the Global Competitiveness Index of Countries
Authors: Akzambekkyzy Akbota , Vasa Laszlo , Forrest Jeffrey Yi-Lin , Sarkambayeva Shynara , Singh Satyanand
Published: April 2024

The concept of project success has evolved from the perspective of conforming to the project triangle to that of benefiting the environment, and then from the perspective of the following generation. Scientists increasingly assert that successful projects require a set of criteria that include such item(s) as future potential. The meaning of project success varies depending on where it is executed. The purpose of this study is to identify whether projects with future potential have a certain effect on indicators of the Global Competitiveness Index (GCI) of the Republic of Kazakhstan (RK) and what other success criteria are inherent in such projects. By using the method of descriptive analysis of data collected from 107 experts and analyzing 19 influential projects, the study revealed that projects oriented towards the future have a significant impact on the indicators of the GCI in the RK. This finding confirms the necessity of considering the long-term sustainability and social significance of projects when assessing their successes. Additionally, a specific combination of success criteria that contributes most to this impact was identified. This research provides a brand-new understanding of project success criteria in the context of their impact on the GCI and emphasizes the importance of considering future potential in project planning and evaluation. Doi: 10.28991/ESJ-2024-08-02-012 Full Text: PDF
Assessment of the Development of the Circular Economy in the EU Countries: Comparative Analysis by Multiple Criteria Methods
Authors: Gedvilaitė Dainora , Lapinskienė Giedrė , Szarucki Marek
Published: April 2024

In recent decades, attention to environmental resource management has increased worldwide. Circular economy (CE) is a concept that is increasingly being considered as a solution to this range of challenges. Therefore, it is important to monitor the development of CE. This research is an attempt to contribute to the CE surveillance literature by providing a framework for comparing the positions of states and their classifications. The main goal of the article is to assess the level of circular economy development in EU countries according to the chosen methodology. The indicators used in this study are sourced from the European Commission Monitoring Framework database, which includes data from 27 European Union (EU) countries over the time frame from 2016 to 2020. The analysis was carried out using Multi-Criteria Decision Methods (MCDM), such as Simple Additive Weighing (SAW), and the objective method of estimating weights in accordance with proportional differences (APROD), which helped to assess the state of CE. The results showed that EU countries can be divided into three groups based on the level of performance of the CE, and their level of development in relation to the circular economy is different. The level of circular economy development in most EU countries is low. Germany, the Netherlands, France, and Italy demonstrated the best positions. The study findings were derived from the combination of two MCDMs, thus increasing the refinement of the overall methodology. Doi: 10.28991/ESJ-2024-08-02-013 Full Text: PDF
Multilingual Question Answering for Malaysia History with Transformer-based Language Model
Authors: Lim Qi Zhi , Lee Chin Poo , Lim Kian Ming , Xiang Ng Jing , Heng Ooi Eric Khang , Ning Loh Nicole Kai
Published: April 2024

In natural language processing (NLP), a Question Answering System (QAS) refers to a system or model that is designed to understand and respond to user queries in natural language. As we navigate through the recent advancements in QAS, it can be observed that there is a paradigm shift of the methods used from traditional machine learning and deep learning approaches towards transformer-based language models. While significant progress has been made, the utilization of these models for historical QAS and the development of QAS for Malay language remain largely unexplored. This research aims to bridge the gaps, focusing on developing a Multilingual QAS for history of Malaysia by utilizing a transformer-based language model. The system development process encompasses various stages, including data collection, knowledge representation, data loading and pre-processing, document indexing and storing, and the establishment of a querying pipeline with the retriever and reader. A dataset with a collection of 100 articles, including web blogs related to the history of Malaysia, has been constructed, serving as the knowledge base for the proposed QAS. A significant aspect of this research is the use of the translated dataset in English instead of the raw dataset in Malay. This decision was made to leverage the effectiveness of well-established retriever and reader models that were trained on English data. Moreover, an evaluation dataset comprising 100 question-answer pairs has been created to evaluate the performance of the models. A comparative analysis of six different transformer-based language models, namely DeBERTaV3, BERT, ALBERT, ELECTRA, MiniLM, and RoBERTa, has been conducted, where the effectiveness of the models was examined through a series of experiments to determine the best reader model for the proposed QAS. The experimental results reveal that the proposed QAS achieved the best performance when employing RoBERTa as the reader model. Finally, the proposed QAS was deployed on Discord and equipped with multilingual support through the incorporation of language detection and translation modules, enabling it to handle queries in both Malay and English. Doi: 10.28991/ESJ-2024-08-02-019 Full Text: PDF
The Effect of Felt Accountability on User Satisfaction with Accounting Information
Authors: Tuan Dang Anh
Published: April 2024

Felt accountability affects an account-givers’ behavior, decisions, and organizational performance. Accounting information (AI) is provided for decision-making and accountability in the public sector. This study investigated the effects of felt accountability on expertise, legitimacy, and AI disclosure level for accountability on users’ satisfaction. Survey data included 401 responses across public institutions in Vietnam, and SEM linear structure analysis was used to examine the results. The research findings indicate that felt accountability directly affects users’ satisfaction and their expertise and legitimacy, and the level of AI disclosure. The expertise and legitimacy of the account-holder and the level of AI disclosure partially mediate the relationship between felt accountability and users’ satisfaction. This implies that AI's needs, purposes, and importance are determined based on hypothetical users that are not useful in reality. In practice, AI must meet accountability requirements to bring satisfaction to users. The satisfaction level of actual users of AI is influenced by the account-givers’ perceived accountability regarding the needs, expertise, and legitimacy of the account-holder. Therefore, it is essential to identify the type of information needed, the timing of AI disclosure, and the actual AI users to reduce the gap between the supply and demand of AI. The research results provide evidence supporting agency and social contingency theories in accountability relationships. Doi: 10.28991/ESJ-2024-08-02-023 Full Text: PDF
Agriculture 5.0 and Explainable AI for Smart Agriculture: A Scoping Review
Authors: Abdul Razak Siti Fatimah , Yogarayan Sumendra , Sayeed Md Shohel , Mohd Derafi Muhammad Izzat Faiz
Published: April 2024

The visionary paradigm of Agriculture 5.0 integrates Industry 4.0 principles into agricultural practices. Our scoping review explores the landscape of Agriculture 5.0, emphasizing the pivotal role of Explainable AI (XAI) in shaping this domain. Guided by the Preferred Reporting Items for Systematic Review and Meta-Analysis Scoping Review, we rigorously analyzed 84 articles published from 2018 to September 2023. Our findings highlight XAI’s potential within Agriculture 5.0, recognizing its influence on intelligent farming. We propose a conceptual framework for integrating XAI, emphasizing its impact on model transparency and user trust. Despite transformative applications, existing literature often lacks XAI discussions. Our objective is to bridge this gap and provide a reference for academics, practitioners, policymakers, and educators in the field of smart agriculture that is both environmentally friendly and technologically advanced. Doi: 10.28991/ESJ-2024-08-02-024 Full Text: PDF
L’ambivalence de L’œuvre genetienne
Authors: Kasap Özlem
Published: April 2024

Jean Genet et son œuvre ont longtemps été sources de controverses. Son œuvre dramatique que des critiques rapprochent des idées d’Antonin Artaud se construit essentiellement autour du « rituel » qui propose une forme authentique de critique sociale surtout dans Les Bonnes (1947), Le Balcon (1956), Les Nègres (1958) et Les Paravents (1961). En détruisant ainsi l’illusion scénique, il rend impossible la distinction du vrai et du faux dans un univers où sont mis sur scène des criminels, des prostituées, des voleurs et des traîtres. Il crée sur la scène théâtrale un univers inverti de valeurs où on se plaît à exalter le mal. Ce mal qui se concentre essentiellement dans « l’acte » et surtout dans « la parole » du personnage se voit représenté, la plupart du temps à travers la figure de l’Autre, dans un excès de haine et de violence gratuite, le tout attisé par la trahison. Ce travail se propose d’étudier, en utilisant les facteurs constitutifs de la dramaturgie genetienne, cette mise en scène du mal et ses diverses facettes, à savoir cette perpétuelle haine sur laquelle se construit l’intrigue. Pour mener à bien cette étude, nous nous baserons sur la conceptualisation de Raymond Federman qui définissait le théâtre de la haine genetien mais aussi sur le goût à la trahison tel que le met en évidence Ivan Jablonka dans son étude Les vérités inavouables de Jean Genet.
Synchronous early rectal adenocarcinoma and neuroendocrine tumour: A treatment strategy
Authors: Alagoo Dinesh , Sellappan Harivinthan , Rajanthran Saravana Kumar , Azizan Nornazirah , Johari Nur Farehah , Zakaria Andee Dzulkarnaen , Hayati Firdaus
Published: April 2024

Introduction

Synchronous colorectal adenocarcinoma with neuroendocrine tumour (NET) are a unique combination of tumours. These may be incidental lesions, usually a histopathological diagnosis rather than a clinical diagnosis from symptoms, examination or even gross appearances.

Aim

This paper aims to highlight our management strategy on manging a middle-aged woman with synchronous rectal adenocarcinoma and NET.

Case study

A 53-year-old woman presented with lower gastrointestinal bleeding with constitutional symptoms. Clinical examination and colonoscopy revealed a classical rectal adenocarcinoma, confirmed via biopsy. However, the final histopathology reports of the resected tumour revealed an early rectal adenocarcinoma with synchronous NET.

Results and discussion

We review the relevant literature and a discussion regarding guidelines available for diagnosis, follow-up and surveillance of this rare case.

Conclusions

There are no current guidelines for surveillance colonoscopy after detecting gastrointestinal NET, particularly synchronous tumours. NET may be another colorectal cancer risk factor with similar mutations and common genetic markers. Clinicians should consider doing a colonoscopy when or if their patients are diagnosed with any gastrointestinal NET. Detection of any NET warrants a thorough evaluation of the whole colon for colorectal cancer and close surveillance so that timely management can be achieved.
The Implementation of Enterprise Resource Planning Informatics Department Education Laboratory
Authors: Suratmanto Bekti , Rahardjo Emanuel Andi Wahju
Published: April 2024

In preparing for the accreditation of units, study programs, and tertiary institutions to achieve a superior rating, Universitas Atma Jaya Yogyakarta (UAJY) often faces challenges in gathering and accessing the necessary resources. These difficulties stem from the accreditation preparation process, ineffective resource management, a lack of data integration, and restricted resource access. Taking advantage of advancements in information technology, UAJY has adopted the ERP Laboratory Information Management System (LIMS) to effectively manage the resources within its educational laboratories. These laboratories serve as a vital support unit in fulfilling the Tri Dharma of Higher Education and play a significant role in enhancing the learning process at the university. Enterprise Resource Planning (ERP) is a strategic tool that can provide organizations with a competitive edge by synchronizing, integrating, and optimizing data. The implementation of ERP LIMS serves as a solution for better resource management within the UAJY Informatics Department's educational laboratories.
Enhancing Customer Experience and Satisfaction through Mobile-Based Salon and Spa Reservations on Android Platforms
Authors: Permatasari Hanifah , Purwanto Eko , Triyono Triyono
Published: April 2024

Salons and spas in Indonesia need to utilize information technology to improve business performance and provide customers with a more personalized experience. The integration of digital reservation systems, online marketing, and technology-based customer management will help improve operational efficiency and gain valuable customer feedback. Digital reservation systems enable salons and spas to improve business performance by providing easy access to customers, increasing the efficiency of scheduling management, and providing a more personalized experience, which is an important strategy in the competitive digital era. One of the alternative digital reservation systems that can be used by salons and spas in Indonesia is Android-based. This research resulted in an Android-based digital reservation system that focuses on customer experience. The object of the research is Spaque Salon & Day Spa, an MSME in Indonesia. Through mobile technology, customers can easily book and manage their treatments. Test results showed positive feedback regarding the user interface, reservation steps, and interactive features. The system also helps with schedule management, additional services, offers, as well as revenue and financial tracking. This research combines customer and technology perspectives, contributing to the salon and spa industry as well as mobile technology developers.
Determining the Factors that Influence e-Marketplace Selection from Seller’s Perspective Using a Binary Logistic Regression Model
Authors: Purwanto Eko , Mohd Farahwahida Binti , Long Zalizah Awang , Purnomo Singgih
Published: April 2024

The rapid development of information and communication technology influences changes in aspects of life in the economic sector. The application of information and communication technology supports business development. The development of the internet has become a technology that makes business activities such as marketing and sales easier. The growth of internet users in Indonesia reached 78% of the total population. E-commerce users in Indonesia reach 34.10% of all business people in Indonesia. One place to sell online is through e-marketplace. Many e-marketplaces require sellers to select e-marketplaces as a place to sell their products online. Each e-marketplace has different characteristics, so you must consider many factors when choosing an e-marketplace. In this research, it is known that two factors are formed based on factor analysis, namely the Product Quality Factor, the Service and Quality Factor, and the System Factor. In addition, the market selection model was determined using binary logistic regression analysis. The model formed in this research is the e-marketplace selection model Tokopedia, Shopee, and Lazada. Based on the results of the feasibility model using binary logistic regression, it produces an overall e-marketplace selection model with an accuracy level of 76.13%. This evaluation model can be used by sellers who want to choose a market that suits the products offered to increase profits.
Iron deficiency in atopy (own data and literature analysis)
Authors: Delyagin V. , Migacheva N.
Published: April 2024

Due to systemic allergic inflammation, intestinal changes, and malnutrition, atopic diseases can be complicated by iron deficiency conditions. Objective. To determine the values of hemoglobin (Hb) and the frequency of anemia in children and adolescents with atopic dermatitis (AD) and asthma and to present the possible causes of the disorders. Results. In 2001, a total of 180 children (mean age 4 years) with AD were examined; their Hb concentration was 109.3±9.8 g/l; of them 77 (43%) children had
The problem of iodine deficiency in children
Authors: Kravtsova O. , Sagitova E. , Averyanov V.
Published: April 2024

The authors analyze the prevalence of thyroid diseases associated with iodine deficiency in children under 14 years of age, by using Registration Form No. 12 “Information on the number of diseases registered in patients living within the service area of a healthcare facility” of children’s polyclinics, Orenburg City Clinical Hospital Five, over 2018–2021. They consider diseases, such as subclinical hypothyroidism due to iodine deficiency and other hypothyroidism forms, endemic goiter associated with iodine deficiency, as well as other forms of non-toxic goiter.
Lung dysplasia in preterm newborn infants: clinical and diagnostic features in the early neonatal period (a clinical case)
Authors: Zavyalov O. , Ignatko I. , Pasechnik I. , Babaev B. , Marenkov V. , Titov V. , Antropova O. , Lebedeva M. , Novikov E.
Published: April 2024

The paper presents modern ideas about the clinical and diagnostic features of lung dysplasia in preterm babies in the early neonatal period. Lung dysplasia is shown to be a common and antenatally diagnosed congenital malformation of the respiratory system. The semiotics of lung dysplasia and respiratory distress syndrome in the newborn is compared. The authors consider the characteristics of the main respiratory patterns of traditional and high-frequency oscillatory ventilation, which are often used for respiratory support for premature babies in the neonatal intensive care unit. They discuss the pathogenetic role of hemodynamically significant patent ductus arteriosus in premature babies with respiratory failure. It is emphasized that for the timely detection of chromosomal abnormalities and congenital malformations in a fetus, it is necessary for pregnant and parturient women to regularly attend antenatal care clinics and to undergo prenatal screening. The paper describes a clinical case that considers the capabilities of diagnostic search and the parameters of monitoring the vital functions of a premature baby in the early neonatal period during intensive care in the neonatal intensive care unit.
The behavioral characteristics of junior schoolchildren (as assessed by their parents) and the resolution of a question about the need to prescribe therapy
Authors: Taranushenko T. , Tepper E. , Meshkova A.
Published: April 2024

The paper presents the results of studying the level of school anxiety among primary school juniorpupils (n=70), by using the data of a parent survey. The study showed that 71.4% of the children displayed personality traits that could identify 5 entities of behavioral disorders. It is noteworthy that the predominant types of behavior were irritability (44.5%), maladaptive responses (42.8%), and increased excitability (20.4%). The parent questionnaire survey could identify a group of children with increased anxiety that had not been previously established and needs to have a closer look due to the high risk of an anxious and neurotic trait type and to the negative impact on the intellectual development of a child and somatic well-being.
Methods for rehabilitation of cancer patients in gynecology
Authors: Petrozhitskaya A.
Published: April 2024

Cancer patients often face serious anatomical, functional, immunological, metabolic, and mental disorders and reduced work and social opportunities resulting from the use of multistage, invasive treatment options. The authors have reviewed literature on various methods for rehabilitation of cancer patients, including gynecological ones, after surgery, radiation, and chemotherapy.
The evolution of the use of bacteriophages in the practice of treating infectious diseases
Authors: Radzhabova Kh. , Dolinnyi S. , Burgasova O.
Published: April 2024

In an era of multidrug-resistant bacterial infections that are depleting the use of chemical antibiotics, and highly effective types of antibiotics are being developed less and less, modern medicine must look for new therapeutic methods to treat infectious diseases. Potential antibacterial solutions include bacteriophage-based therapeutics, which have very different properties from the broad-spectrum antibiotics that are currently the standard of care and can be used in combination with them, often in synergy. This review traces the evolution of the development of approaches to bacteriophage therapy and outlines ways to introduce phage therapy into the practice of modern medicine
The Role of Sharia Pawnshop in Supporting The Growth of The Halal Industry: Opportunities and Challenges
Authors: Husna Arinal , Asytuti Rinda , Ramadhani Diva Nimas , Rosalita Dwi Mukti
Published: April 2024

This research discusses the role of sharia pawnshops in supporting the strength of the Islamic financial ecosystem through the halal industry. The halal industry continues to develop rapidly in this era so the role of sharia pawnshop is not overlooked in its development. This research uses a qualitative research method that uses a descriptive analysis approach that uses various sources regarding the Sharia financial ecosystem, halal business, and the function of Sharia pawnshops in facilitating the Islamic financial ecosystem. This research explains that Sharia pawnshop can be a financial solution regarding limited capital and household economics. MSMEs are an indicator of contributing to GDP in countries that are experiencing difficulties with bank loans. Sharia pawnshop can provide capital loans with fairly easy conditions, one of which is the BPKB Ar-rum product. This research found that Sharia pawnshop has carried out a lot of promotion and education to increase public interest in Sharia pawnshop through offering benefits and in-depth understanding. This is proven by innovations in Sharia pawnshop products. Qardhul Hasan, ijarah, musyarakah, ba'i muqayyadah and murabahah-based financing in sharia procurement really supports the development of the halal industry.
Promosi Melalui Endorse Pada Produk Kosmetik Wardah Ditinjau Dari Perspektif Bisnis Syariah (Studi Kasus Pada Mahasiswa Fakultas Ekonomi dan Bisnis Islam UIN Fatmawati Sukarno Bengkulu)
Authors: Effrianti Yeka , Wahyuni Eka Sri
Published: April 2024

This study aims to  determine promotion through endorsement in increasing consumer buying interest in wardah cosmetic products and the application of sharia business principles in the promotion of endorsement on wardah cosmetic products. This study used descriptive qualitative research method. Data collection techniques of interviews, observation and documentation. Data analysis techniques use descriptive analysis with stages of data reduction, data presentation, and conclusion. The result of this study  is that promotion through endorsements on wardah cosmetic products is very influential in increasing consumer buying interest if done honestly, transparently, and with good and correct descriptions and ways. Therefore, honesty, transparency in endorsing and also describing products well are needed in promoting products with endorsements. Viewed from the perspective of sharia business, the promotion of endorsement on wardah cosmetic products carried out by Dewi Sandra is able to increase consumer buying interest and has also fulfilled the principles of sharia business in promoting by endorsing wardah cosmetic products.
Pengaruh Sikap, Norma Subjektif, dan Religiusitas Terhadap Preferensi Halal Pada Produk Kosmetik di kalangan Gen Z
Authors: Hakiki Habibillah , Priantina Anita
Published: April 2024

The aim of this study is to analyse the influence of attitudes, subjective norms and religiosity on halal preferences for cosmetic products, with a focus on Generation Z. Using a quantitative method with an SEM-PLS approach, this study collected primary data from Generation Z respondents who purchased halal cosmetic products. The analysis shows that attitudes, subjective norms and religiosity together have a significant influence on halal preferences, allowing a deeper understanding of the factors that influence purchasing decisions in this context. The findings of this study provide valuable insights for marketers of halal cosmetic products to develop more targeted and effective marketing strategies to reach Generation Z consumers. Nevertheless, this study has limitations, such as geographical restrictions and not taking into account certain external variables. Therefore, it is recommended for future research to expand the scope and consider additional external factors. To summarise, this study should provide a basis for developing smarter marketing strategies that address halal preferences in cosmetic products in the digital age.
EDUCAÇÃO EM SAÚDE ACERCA DE INFECÇÕES SEXUALMENTE TRANSMISSÍVEIS: UM RELATO DE EXPERIÊNCIA
Authors: PAIVA MARINA FARIAS DE , Silva Maria Eduarda Santos da , Sampaio Ruan Ferreira , Martins Danilo Rodrigues , Santos Ricardo Giorges Soeiro Dos
Published: April 2024

Introdução: A educação em saúde, assim como a promoção e prevenção, é uma estratégia básica e indispensável a melhora dos indicadores e determinantes sociais em saúde, uma vez que melhorando o acesso
Abordagem inicial no paciente traumatizado evidenciando a etapa pré-hospitalar
Authors: Mizael Ana Julia Medeiros , Salles Maria Eduarda Pereira
Published: April 2024

Introdução: O atendimento ao paciente traumatizado é baseado em sua fisiologia, priorizando a oxigenação e ventilação da vítima.1 É um processo crítico que começa no momento do incidente e continua ao
Sites and Zones of Maximum Reactivity of the most Stable Structure of the Receptor-binding Domain of Wild-type SARS-CoV-2 Spike Protein: A Quantum Density Functional Theory Study
Authors: Ernesto López-Chávez , Alberto García-Quiroz , Yesica Antonia Peña-Castañeda , José Antonio Irán Díaz-Góngora , José Alberto Mendoza-Espinosa , J Antonio López-Barrera , Fray de Landa Castillo-Alvarado
Published: April 2024

Today, it is well known that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has four types of proteins within its structure, between them the spike protein (S). The infection mechanism is carried out by the entry of the virus into the human host cell through the S protein, which strongly interacts with the human cell receptor angiotensin-converting enzyme 2 (ACE2). In this work, we propose an atomic model of the Receptor Binding Domain (RBD) of the S spike protein of the wild-type SARS-CoV-2 virus. The molecular structure of the model was composed of 50 amino acids that were chemically bonded, starting with Leucine and ending with one amino acid Tyrosine. The novelty of our work lies in the importance of knowing the sites and zones of maximum reactivity of the RBD from the fundamental levels of quantum mechanics considering the atomic structure of matter. For this, the local and global reactivity indices of the RBD were calculated, such as frontier orbitals, Highest Occupied Molecular Orbital (HOMO) and Lowest Unoccupied Molecular Orbital (LUMO), Fukui indices, chemical potential, chemical hardness, electrophilicity index; with this, it will be possible to know what type of molecules are more likely to interact with the RBD structure, and in this way, new knowledge will be generated at the quantum, atomic and molecular level to inhibit the virulent effects of wild-type SARS-CoV-2. Finally, in order to identify the functional groups within the most stable structure and thereby verify the future reactions that can be carried out between the RBD structure and biomolecules, the Infrared (IR) absorption spectrum was calculated. For this work, we used Material Studio v6.0 which uses the density functional theory (DFT) implemented in its DMol3 computational code. The IR spectrum was obtained using the Spartan ‘94 computer code. One novelty would be that we found nine amino acids more that could make the RBD and ACE2 binding further the already known. Thus, the Mulliken charge distribution indicates that the highest concentrations of positive and negative charge are found in the zones 477S, 478T, 484E, and 501N amino acids letting ionic or Van der Waals possible interactions with other structures.
Hearing screening in video game players with headphones use
Authors: NP Oktaviani Rinika  , W Lolik Lesmana  , KS Pradnyana Putri
Published: April 2024

Background: Hearing loss due to noise can cause by entertainment activities. Loud noise resulting from use of earphones with excessive volume and for long periods threatens the safety of the user's hearing. Purpose: To determine the hearing function of video game players who use headphones. Methods: This research is a descriptive study with a cross-sectional design. Hearing function of the players were carried out using pure tone audiometry. Results: Total of 56 subjects were male (100%) and 66.1% subjects had used headphones for <12 months, 7.1% for 12-24 months and 26.8% for >24 months. As many as 87.5% subjects were exposed to headphone noise for <3 hours per day, 10.7% subjects for 4-6 hours per day and 1.8% for >6 hours per day. The volume level of headphones gamers was mostly set at 6 (39.3%). Based on pure tone audiometry, all subjects had normal hearing thresholds at low frequencies (500Hz and 1000Hz) and medium frequencies (2000Hz and 4000 Hz). Only 3 subjects (5%) had an increase of hearing threshold at high frequencies (6000Hz and 8000Hz). Conclusion: The hearing thresholds for each ear in video game players who use headphones based on frequency groups were identified in this study. An increase in hearing threshold in gamers could be an early sign of hearing loss, then hearing conservation education program should be considered for active gamers.