bluuebunny/crossref_metadata_2025 huggingface dataset:
Las quebradeiras de coco babaçu y las nuevas narrativas emergentes en contra del Matopiba en el Médio Mearim-Maranhão
Authors: Aragão Guimarães Costa Michelly , Medeiros Jalil Laeticia , Bidaseca Karina
Published: June 2023

This article investigates how women who break babassu palm nuts have been impacted by the Brazilian government’s Matopiba development efforts in the Médio Mearim area of Maranhão, northeastern Brazil. The main characteristics of the agribusiness model in the region are examined together with its new form of territorialization (from expanding the agricultural frontier), along with the strategies and collective actions used by the babassu nut breakers against these projects. We utilized semi-structured interviews with leaders of the Interstate Babassu Nut Breakers Movement (Movimento Interestadual das Quebradeiras de Coco Babaçu, MIQCB) who play a prominent role in defending the territory and shaping the social and community fabric of the Médio Mearim region; specialized reports, previous studies, and audiovisual sources were also reviewed. Self-organization of women through the MIQCB has been one of their main strategies for (re)existence and collective action to combat the impacts of agribusiness on their bodies/territories and communities. The babassu nut breakers are political individuals who generate new emerging narratives through agroecology, cooperativism, food sovereignty, and rural and popular feminisms to combat increasing deforestation of babassu palms, socio-environmental conflicts, and violence in this region.
Uma análise interseccional das estratégias e resistências mobilizadas por mulheres negras em um assentamento de reforma agrária no sul de Minas Gerais
Authors: Ventura Bambirra Natércia , Rosas Magrini Pedro
Published: June 2023

A política de assentamento de pessoas em curso no Brasil reproduz uma lógica histórica de marginalização que afeta sobremaneira as mulheres negras. Neste estudo de caso realizado no Assentamento Santo Dias (Guapé/MG), foram identificados nas histórias de vidas das assentadas entrevistadas, majoritariamente mulheres negras, alguns dos diversos desafios enfrentados por elas. Não obstante, também foi possível levantar algumas das estratégias e resistências que as assentadas mobilizavam em um contexto marcado por “discriminações interseccionais” com base no gênero, raça/etnia e classe. No presente artigo, o principal objetivo consistiu na análise das estratégias e resistências de mulheres negras assentadas. Para tanto, a interseccionalidade foi utilizada como ferramenta analítica e teórica, em uma perspectiva interdisciplinar. A metodologia está pautada nas epistemologias feministas e antirracistas a partir de abordagens qualitativas para estudo de caso, história de vida e observação participante. Na pesquisa ficou demonstrada a urgência da pauta por autonomia econômica, atravessada por questões de gênero e raça/etnia. Também restou evidente, a necessidade do desenvolvimento de políticas públicas interseccionais construídas com e para os diferentes grupos que compõem os rurais. E a curto prazo, a promoção da garantia do acesso eficiente e célere ao Contrato de Concessão de Uso da terra (CCU), ao Crédito Instalação e as devidas medidas de estruturação de modo a tensionar a situação de vulnerabilidade das mulheres e de suas famílias.
Labour Welfare and Social Security Measures in Selected Industries of Goa
Authors: - Jadhav Hemlata Roopsing , - N.S.Mugadur
Published: June 2023

International Labour Organisation (ILO) at its Asian Regional Conference, defined Labour Welfare as a term which is to include such services, facilities and amenities as may be established in or in the vicinity of undertakings to enable the persons employed in them to perform their work in healthy, congenial surroundings and to provide them with amenities conducive to good health and high morale. The objectives of the study are; to examine the socio-economic condition of workers in selected industries in Goa, to analyse the Labour welfare and social security measures in Selected Industries in Goa. The Hypotheses of the study are; there is no significantant difference between labour welfare facilities and Selected Industries in Goa and there is a significant difference between social security measures and Selected Industries in Goa. It is based on primary data only. The primary data was collected based on Interview Schedule method and a sample size of 204 Workers. The present study is based on Stratified Random Sampling Method. The study period is June 2022. The Statistical tools used in the study are Percentage and Non-Parametric Test i.e. Kruskal-Wallis Test. The study proved that Labour Welfare facilities and Social Security Measures to the workers in Selected Industries in Goa was found satisfactory. If the workers in industries are satisfied with the Labour Welfare facilities and Social Security Measures then there will be no industrial Disputes in the Industries and also harmonious relations between workers and the management. It not only increases productivity but it may add to satisfaction with the industry and cut down labour turnover.
A Systematic Review on Cyclodextrin: A Versatile Tool for Enhanced Formulations and Diverse Applications
Authors: - Ankit Choudhary , - Anup Jyoti Roy , - Kundan Dutta , - Jon Jyoti Sahariah , - Hans Raj Bhat
Published: June 2023

Cyclodextrins (CDs) are cyclic oligosaccharides that have gained significant attention in various industries due to their unique structural properties and versatile applications. This study aims to provide a comprehensive overview of the types, formulation techniques, and wide-ranging applications of cyclodextrins. It explores the formulation techniques used to incorporate cyclodextrins into different matrices. Cyclodextrin Complex Formation, Cyclodextrin-Based Nanostructures involves the encapsulation of guest molecules within the hydrophobic cavity of cyclodextrins. The study presents a broad range of applications where cyclodextrins have demonstrated their utility. The pharmaceutical industry extensively employs cyclodextrins as excipients to enhance drug solubility, stability, bioavailability, and taste masking. Additionally, CDs find applications in the food and beverage industry for flavor encapsulation, preservation, and controlled release of bioactive compounds. They also play a vital role in various fields, including agriculture, cosmetics, environmental remediation, and separation sciences.
Study on Consumer Buying Behavior of Ceramic Tiles using Multi-criteria Decision Making
Authors: - Somarata Chakraborty , - Sweta Rani
Published: June 2023

The main purpose of this research work is to explore the consumer priorities, preference of consumers on buying Ceramic Tiles. The study will also focus on understanding the key factors which triggers the consumers purchasing decision of ceramic tiles. A detailed study has been planned to identify the different criteria which will be the deciding factors of selecting ceramic tiles from a particular brand. Comparison has been made by considering some leading brands available in Indian market in the ceramic manufacturing and business. Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) as a multi criteria decision making (MCDM) tools has been used to accomplish the research objectives.
Hattiyangadi Narayanaroys "Angla Kavitavali"
Authors: - Sowmya.KC
Published: June 2023

Hattiyangadi Narayanarao's literary work is remarkable in the modern Kannada literary era. His Angla Kavitavali is an important work in the modern context and an overview of this work is done in the present article.
Fogging is a Puerile Exercise: A Preliminary Study Done in the City of Kolkata, India, Following the Outbreak of DF/DHF in 2017, Has Revealed
Authors: - Debashis Biswas
Published: June 2023

In 2017, the impact of fogging on transmission of dengue was studied in Kolkata City, India. As revealed, the measure failed to yield any positive results. Despite the massive fogging being carried out in different municipal wards, no sign of reduction in the number of dengue cases was visible. At the behest of Atin Ghosh, deputy mayor [erstwhile mayoral council member [health] of Kolkata Municipal Corporation, the fogging was banned in 2019 and an era of vector management by applying all possible means of source reduction brought in.
Revolutionizing Program Evaluation with Generative AI: An Evidence-Based Methodology
Authors: - Drijesh Patel
Published: June 2023

Revolutionizing Program Evaluation with Generative AI: An Evidence-Based Methodology
A Study of Dietary Practices and Nutritional Awareness among Adolescent Girls of Ranchi District (Jharkhand)
Authors: - Anjali Chandra , - Shingla Prabha
Published: June 2023

The World Health Organization (WHO) defines an adolescent as any person between ages 10 and 19 years. Adolescence is characterized by the growth spurt, a period in which growth is very fast. During this time, the body's nutritional needs are affected by the physical development, while changes in one’s lifestyle may also affect eating habits and food choices. Adolescence is the transition period between childhood and adulthood, a window of opportunity for the improvement of nutritional status and correcting poor dietary practices. Good nutrition is therefore very important for the proper growth and development and the prevention of any health problems in adolescents in the future. Thus, in the present study, an attempt was made to study the Dietary practices and awareness level of the adolescent girls. The study was conducted in rural and urban areas of Ranchi district of Jharkhand state. Self -made questionnaire was used to assess the level of Nutritional awareness and dietary practices of adolescent girls of Ranchi district. The survey method of research was used to get the desired information in the study. Two hundred adolescent girls of 13 to 17 years of age were selected through simple random sampling technique. Findings showed that when compared to urban adolescents, rural adolescents were less informed and have less awareness about health and Nutrition. The majority of rural adolescent girls have poor dietary practices and moderate nutritional awareness and in urban area majority of the respondents have relatively better nutritional awareness. Nutritional awareness has impact on dietary practices of adolescents, which also adversely affects their health. So, adolescent girls need nutrition education to improve their knowledge and nutritional awareness.
Melanosis Detection using Machine Learning from Basal Cell Carcinoma
Authors: - Mr. Ashwin Raju Dhanorkar , - Dr. Amit K. Gaikwad
Published: June 2023

Basal cell carcinoma (BCC) is the most common type of skin cancer, and early detection is crucial for successful treatment. Dermoscopy is a widely used technique for the diagnosis of skin lesions, which provides high-resolution images of the skin surface. However, the diagnostic process is still based on the visual inspection of the images by a dermatologist, which can be subject to human error. In recent years, machine learning techniques, particularly convolutional neural networks (CNNs), have been applied to the analysis of dermoscopic images with promising results. In this Paper, we propose a method for detecting BCC using CNNs on dermoscopic images of melanocytic skin lesions. Melanosis detection from basal cell carcinoma is a crucial task in the field of dermatology. In this Paper, we proposed a machine learning-based approach for the automatic detection of melanosis from basal cell carcinoma. We collected a dataset of dermoscopic images of basal cell carcinoma lesions, and our proposed method extracts features from these images and trains a deep learning model to detect melanosis.
Monitoring and Controlling Hydroponic Units using IoT
Authors: - PRASHANT CHANDRASHEKHAR NIKOSE , - Jayant P Mehare
Published: June 2023

The use of hydroponic systems for growing crops is becoming increasingly popular due to its efficiency and sustainability. However, monitoring and controlling these systems can be challenging and time-consuming. This is where the Internet of Things (IoT) comes into play, as it allows for the real-time monitoring and control of hydroponic systems from anywhere at any time. In this paper, we explore the use of IoT for monitoring and controlling hydroponic units, including sensors for measuring various parameters such as pH, temperature, and nutrient levels, and actuators for controlling water and nutrient supply. We also discuss the advantages of using IoT for hydroponic farming, such as increased yield and reduced resource usage, as well as potential challenges and future research directions. Overall, this paper provides a comprehensive overview of the use of IoT in hydroponics and its potential to revolutionize modern agriculture.
A Novel Approach to Web-based Review Analysis using Opinion Mining
Authors: - Miss. Rashmi Murlidhar Papalkar , - Dr. Amit K. Gaikwad
Published: June 2023

The propose an advanced Website Evaluation system that rates the website based on the opinion of the user. Website will be evaluated based on factors such genuineness of the website, timely delivery of the product after online transaction and support provided by the website. User will comment about the website, based on the comment system will rate the website. The system takes opinion of various users, based on the opinion; system will decide whether the website is genuine or not. The system uses opinion mining methodology in order to achieve desired functionality. We use a database of sentiment based keywords along with positivity or negativity weight in database and then based on these sentiment keywords mined in user comment is ranked. The system contains keywords related to fraud, genuineness, timely delivery of the product and service meters in the database. Based on these factors system will rate the website.
PENGARUH MEDIA QUIZIZ TERHADAP PEMAHAMAN MATERI PENDIDIKAN PANCASILA KELAS I DI SDN BUGANGAN 03
Authors: Azzahra Azzahra Obellia Permata Sari , Mudzanatun  , Indiati Intan
Published: June 2023

Pendidikan pancasila sangat penting untuk dipelajari anak sekolah dasar kelas I di SD N Bugangan 03 untuk meningkatkan perilaku yang baik dalam kehidupan sehari-hari baik di lingkungkan sekolah ataupun di masyarakat. Hal tersebut dapat dilakukan dalam berbagai cara untuk peserta didik mampu memahami pendidikan pancasila,salah satu caranya yaitu menerapkan pembelajaran menggunakan quiziz yang bernilai edukasi diharapkan peserta didik dapat belajar dengan inovatif sehingga akan lebih mempermudah dalam melaksanakan pembelajaran Pendidikan Pancasila serta dapat meningkatkan prestasi belajar siswa .Tujuan penelitian ini adalah untuk mengetahui pengaruh media quiziz terhadap pembelajaran pendidikan pancasila terhadap hasil belajar siswa kelas I di SD N Bugangan 03 Semarang. Hasil uji normalitas data menunjukkan bahwa nilai pretest dan posttest berdistribusi normal. Dibuktikan dari Sig. pretest 0,069 dan Sig. posttest 0,44 yang nilainya > nilai α sebesar 0,05. Uji hipotesis pertama berupa uji t (paired sample t-test) menunjukkan adanya pengaruh dilihat dari Lower dan Upper bernilai negative yaitu Lower sebesar -28.11005 dan Upper sebesar -21.51495. Nilai Sig. (2-tailed) senilai 0,000 yang artinya < 0,05 dan uji hipotesis yang kedua berupa uji t (One Sample t-test) menunjukkan bahwa ada perkembangan dilihat dari Asymp (2 tailed) < α maka nilai Asymp (2 tailed)  = 0,000 < 0,05 dengan Kriteria pengujian yang berlaku yaitu Ho akan ditolak maka Ho ditolak dan Ha diterima.
PENGARUH MENGGAMBAR TERHADAP KEMAMPUAN MENULIS ANAK USIA 5-6 TAHUN
Authors: Ramadhanti Nina , Asmawati Luluk , Maryani Kristiana
Published: June 2023

Writing is a complex activity that requires a well-coordinated interaction of motor and visual skills. Writing skills are process and result skills. So it is difficult for early childhood to master because writing is not owned by children, it must go through processes and stimuli that take a long time for children to produce writing. Children aged 4 to 6 need to practice their fine motor skills to develop their writing skills. This study aims to determine the effect of drawing on the writing ability of children aged 5-6 years. This research uses quantitative methods (quasi experiment) with Nonequivalent Control Group Design. This study used two samples, experimental group and control group, each consisting of 12 children aged 5-6 years, and given different treatment. Based on the results of data analysis using SPSS Statistics version 25 with the t-test in the form of a paired sample t-test in the experimental group it is known that the Sig. (2-tailed) is 0.000 < 0.05, so there is a significant effect, thus Ho is rejected and Hi is accepted. Further, change after treatment from the experimental group in the pretest to the posttest up by 12.17, while in the control group the change from pretest to posttest increased by 7.86, are known that the biggest change was in the experimental group with drawing treatment on children's writing abilities. It can be concluded that there is an influence of drawing on early childhood writing abilities.
PENINGKATAN HASIL BELAJAR IPS MELALUI MODEL PEMBELAJARAN PROBLEM BASED LEARNING KELAS V SDN 28 PADANG SARAI
Authors: Miranda
Published: June 2023

This study aims to improve social studies learning outcomes through a problem-based cooperative learning model for fifth grade students at SD Negeri 28 Padang Sarai for the 2022/2023 academic year. The research subjects for this class action were fifth grade students at SD Negeri 28 Padang Sarai for the 2022/2023 academic year as many as 32 students as recipients of the action, while for the subject of the action participants were social studies teacher class V as a teacher, colleagues as subjects who observed the learning process, The Principal as the subject of the data source. Methods of data collection is done through test techniques, observation and documentation. This Action Research was conducted in two cycles, each cycle consisting of: planning, action, observation and reflection. The results of this study indicate that the use of the problem-based learning model can improve social studies learning outcomes for fifth grade students at SD Negeri 28 Padang Sarai in the 2022/2023 academic year. This can be seen from the average score of social studies learning outcomes for students also increased, namely before the action of 70.19, in the first cycle of 76.38, and in the second cycle of 82.28. In addition, the percentage of student learning completeness, namely before the action was 34.38%, in cycle I was 68.75% and in cycle II was 96.88%.
STRATEGI PEMBELAJARAN AFEKTIF DALAM PEMBINAAN KECERDASAN EMOSIONAL PESERTA DIDIK DI KELAS IV SEKOLAH DASAR
Authors: Indriani Rini , Nurhasanah Ana , Syachruroji A.
Published: June 2023

This research is based on the importance of emotional intelligence in students. Not only intellectual intelligence but emotional intelligence is equally important. In this study aims to provide an overview of the affective learning strategy of the consideration model in developing students' emotional intelligence and its impact. This study uses a descriptive qualitative approach, the data used are interviews, observations, and documentation. The subjects studied were teachers as homeroom teachers for class IV and students in class IV at SDN Citangkil Baru, Cilegon City. The result of this research is that the teacher's efforts in fostering emotional intelligence are the affective learning of the consideration model, namely the learning steps of the consideration model. The impact of the consideration model of affective learning is to improve students' social skills, inculcate an attitude of tolerance, increase positive mindsets such as being responsible, mutual cooperation, caring for one another.
PENGUATAN KREATIVITAS SISWA MELALUI KEGIATAN PANGGUNG KREATIVITAS DI SDN KARANGANYAR GUNUNG 02
Authors: Widyayati Windi , Wakhyudin Husni , Miyono Noor , Riskiyati Nur
Published: June 2023

This study aims to analyze the creativity of students at school through routine habituation of the creativity stage at SDN Karanganyar Gunung 02. Education in elementary schools has an important role in developing student creativity, one way to develop student creativity is through habituation to the creativity stage. The creativity stage is a routine activity carried out to develop the creativity and talents and interests of students. There is a correlation between the habituation of the creativity stage at SDN Karanganyar Gunung 02 every Tuesday and the students creative abilities. The positive correlation is the stage of creativity as forum for developing the creativity of students through performances or performances that are carried out in turn from each clas, besides that the stage of creativity can also foster self confidence and hone studens interest and talents in creating. Teachers can develop students creativity by providing activities according to the needs and interest of students, through the creativity stage students can be taught to choose and determine what the will do to appear, the appearance of students is adjusted to their ideas and creativity and their creations are in accordance with tehe wishes of the participants educate.
Pengaruh The Theory of Planned Behavior terhadap Minat Beralih Menggunakan Kemasan Ramah Lingkungan
Authors: Reynaldi Muhammad , Lita Ratni Prima , Maruf
Published: June 2023

This study aims to determine the intention to adopt green packaging at coffee shops in Padang City. This study uses the theory of planned behavior (TPB) to predict the intention of coffee shop entrepreneurs to use environmentally friendly packaging. The sample in this study is a coffee shop business actor who is not a national franchise in the city of Padang. The results of this study are expected to be able to find out how much coffee shop businesses in Padang City want to use environmentally friendly packaging. This is also expected to be able to reduce plastic waste in the city of Padang.
Pré-operatório de coluna lombar e suas principais estratégias de intervenção: revisão integrativa
Authors:   Carolyne Carvalho Caxias; José Victor Carvalho Costa; Marcos Vinício Lopes Barros; Caio César de Sampaio Caetano Lima; João Pedro de Oliveira Resende; Yago Felipe Rodrigues Pinto; Francisco Lopes Barros; Johnathan Allyson Quariguasi Ferreira; Andrei Iago Gonçalves Viana Soares Feitosa; Laire de Souza Oliveira and Marília Marques Capucho do Vale Leite
Published: June 2023

Introdução: A ideia teórica subjacente à pré-habilitação é que o aumento da capacidade funcional antes da cirurgia levará a uma recuperação mais rápida. Objetivo: Descrever as principais estratégias na reabilitação de pacientes submetidos à cirurgia na coluna lombar, com ou sem artrodese, por hérnia de disco, espondilolistese ou estenose. Além do mais avaliar os resultados dessas intervenções nos parâmetros dor, função e incapacidade. Materiais e Métodos: O presente estudo trata-se de uma revisão bibliográfica. A revisão foi baseada em artigos indexados nas bases de dados PubMed e Cochrane Library, na qual utilizou-se as palavras-chave: Pré operatório; coluna lombar; fisioterapia. Bem como seus respectivos em inglês: Preoperative; lumbar spine; physical therapy. Incluídos artigos randomizados publicados nos últimos 05 anos. Resultados: 48 artigos foram encontrados e 04 selecionados, onde desenvolveram como base terapêutica as terapias por exercício, baseado em movimento específico, controle motor, força e cardiovascular, além da terapia cognitiva comportamental. Conclusão: Não está claro que tipo de programa de pré-operatório é o mais eficiente.
Efforts to Improve Computational Thinking in Science Learning Through Canva Application
Authors: Novianti Nita , Dewi Nastitisari
Published: June 2023

This research is conducted driven by the low manifestation of learning skills of the 21st century and the era of the industrial revolution 4.0. This can be observed from the low ability of students in computational thinking skills (Representation/Abstraction, Decomposition, Algorithms, Pattern recognition) in working on questions. In addition, students are more attracted to play with their smartphones than learning. The purpose of this study is to analyze efforts to improve students' computational thinking skills through the application of the digital canva application to the topic of “Environmentally Friendly Technology". The subject of the study was class IX, randomly selected from a Public Middle School in Sukabumi City using two learning cycles which saw an increase in the results of the learning process. The results of the study show that there has been an increase in the computational thinking skills 38% of students achieved minimum completensess criterion scor in cycle 1 and to 77% did in cycle 2. The indicators of computational thinking skills that can be developed in cycles 1 and 2 are Abstraction, Decomposition, Algorithms , and Pattern Recognition. The increase in learning outcomes (gain) for each computational thinking skills indicator in cycle 2 was greater than in cycle 1 because there were efforts by the teacher to improve the learning process.
Efforts to Improve Environmental Attitudes of Students using Problem Based Learning Model
Authors: Dewi Nastitisari , Novianti Nita
Published: June 2023

Background: a student's attitude of care for the environment is either a affective competence or the value of a outlook on life that the student has in addressing conditions that are occurring in his or her surroundings. The purpose of this best practices is in an effort to improve the viic grade affective competencies in the neighborhoods in the junior state of sukabumi. Method: this study applies the class action study method with a quantitative approach to study subjects of 38 students. The instruments used are the beneficiary competence competencies of learners to the ward, teacher and student interviews, and student responses to learning. The affective competence of participants based on this study includes 3 indicators of 1) being conscious and thankful, 2) being curious, critical thingking, and caring for the environment, and 3 being prudly employed by materials that could polluter the environment. Results: research shows cycle I that the average percentage of the scores of positive attitudes of concern students have toward the environment increased after applying the model of learning problem based learning from 56.08% to 66.71%. And the average percentage of students' negative towards the environment is declined after a model of learning problem based learning from 43.92 % to 33.29%. Then, at the second cycle, treatment is remitting by using a different mind mapping on learning, and the average percentage of the score of the students' positive attitude toward the environment is increasing after the model of based learning problem is implemented, using the mind mapping has increased from 66.71% to 86.02%. Conclusion: faculty competence after treatment of learning with the problem of based learning has increased by 66.71%, learners respond favorably to learning the problem of based learning. In this case learners feel motivated to actively study, be active, increase curiosity and improve students' affective competence in the ward.
Keywords : Classroom Action Research; Afectiv; Problem based Learning; Climate Change
AUDIO VISUAL MOTION RHYTHM MUSIC ON THE ABILITY TO BRUSH TEETH OF CHILDREN WITH DISABILITIES
Authors: Sagara Suriakusumah  , Samjaji  , Agung Widyagdo
Published: June 2023

Maintenance of dental and oral health in children with mental retardation is usually still relatively lacking, one of which is in children with mental retardation. Mentally restarded children need to be given more efforts to maintain their oral health in order to keep their oral hygiene healthy. The research: objective to examine the effect of  counseling using audio visuals on the ability to brush teeth of mentally retarded children in cineam SLBN Tasikmalaya district. Research method: using a quasi-experimental research design with one group pre- test and post-test designs. Sampling by Saturated sampling technique, a sampling technique if all of the population are used as a sample. Total sample as many as 30 people. The research measuring instrument used a questionnaire and observations sheet. Data analysis used the wilcoxon test. Research result: post the study after being given counseling using music rhythmic motion audio, it was found that the average ability to brush the teeth of mentally retarded children increased from 3.60 to 2.85. wilcoxon test results obtained p-value= 0,000 (<0,05). The conclusion: is that there is an effect of counseling using audio visual music rhytmic movements on the ability to brush the teeth of mentally retarded children at SLBN Cineam, Tasikmalaya Regency.
KNOWLEDGE OF PARENTS' DENTAL AND ORAL HEALTH MAINTENANCE WITH THE STATUS OF ORAL HYGIENE OF CHILDREN WITH MENTAL RETARDATION
Authors: Poppy Sundari Putri  , Tita Kartika Dewi  , Lina Rismayani
Published: June 2023

Background: Children with mental retardation have trouble taking care of their own dental health, making parental involvement extremely important in directing, offering understanding, reminding, and providing facilities for children to be able to take care of their teeth and oral hygiene. Objective: The purpose of this research was to examine the dental hygiene status of children with mental retardation at SDLB-C Yayasan Bahagia Tasikmalaya City in connection to their parents' knowledge of dental and oral health maintenance. Methods: A cross-sectional study based on a series of observations. Fifteen families with children who have mental disabilities were selected for the study through a purposive sampling method. A questionnaire and the Spearman rank correlation coefficient from the OHI-S.test are utilized for analysis. Results: The test's significance value was 0.029 0.05, indicating that there is a statistically significant association between parental education and dental health in children with mental impairment. Conclusion: Parents' knowledge has a strong relationship with the oral hygiene status of mentally retarded children at SDLB-C Yayasan Bahagia Tasikmalaya City, with coefficient correlation value 0,563.
ANALYSIS OF THE IMPACT OF DIABETES MELLITUS ON PERIODONTAL NETWORK CONDITIONS OF OUTSIDE PATIENTS
Authors: Gresty Grestella  , Eliati Sri Suharja  , Aan Kusmana
Published: June 2023

Background: diabetes melitus is a chronic disease that affects patients throughout their life. About 80% of diabetes melitus patients have problems with their gums. Uncontrolled diabetes melitus can weaken the immunity of periodontal tissue, on the other hand, untreated periodontal disease will worsen blood sugar balance so that periodontal tissue damage will occur. The purpose of the study: to determine the analysis of the impact of Diabetes melitus on the condition of periodontal tissue in outpatients at UPT Puskesmas Cihurip, Garut Regency. Methodology: the method used is qualitative observational with descriptive analytic design, a population of 30 patients who visited cases of diabetes melitus, sampling using accidental sampling. Data analysis used statistical test with ANOVA test. The results of the study: diabetes melitus in outpatients with type 1 DM classification was 16 people (42.1%) while those including type 2 DM were 22 people (57.9%). Periodontal tissue conditions of outpatients mostly included periodontitis criteria as many as 26 people (68.4%) and criteria with gingivitis as many as 12 respondents (31.6%). Analysis of the impact of diabetes melitus on the periodontal tissue condition of outpatients obtained p-value = 0.000 (p<0.05), meaning that there are differences in diabetes melitus in periodontal tissues including gingivitis and periodontitis. Conclusion: There is an analysis of the impact of diabetes melitus on the condition of periodontal tissue in outpatients. It is recommended for puskesmas, especially dental therapists, to further improve counseling for people with diabetes melitus about the importance of maintaining oral and dental health.
Numerical Semigroups, Polyhedra, and Posets III: Minimal Presentations and Face Dimension
Authors: Gomes Tara , O'Neill Christopher , Torres Davila Eduardo
Published: June 2023

This paper is the third in a series of manuscripts that examine the combinatorics of the Kunz polyhedron $P_m$, whose positive integer points are in bijection with numerical semigroups (cofinite subsemigroups of $\mathbb Z_{\ge 0}$) whose smallest positive element is $m$. The faces of $P_m$ are indexed by a family of finite posets (called Kunz posets) obtained from the divisibility posets of the numerical semigroups lying on a given face. In this paper, we characterize to what extent the minimal presentation of a numerical semigroup can be recovered from its Kunz poset. In doing so, we prove that all numerical semigroups lying on the interior of a given face of $P_m$ have identical minimal presentation cardinality, and we provide a combinatorial method of obtaining the dimension of a face from its corresponding Kunz poset.
Maker Conversation: Successes and Challenges in a University SALC
Authors: Taube-Shibata Jamison , Lorentzen Andria
Published: June 2023

This paper discusses the implementation of Maker Conversation, a self-access learning space in a university’s Self-Access Learning Center (SALC) during the 2022 academic year. Maker Conversation is aimed at promoting English language use among students through science, technology, engineering, art, and mathematics (STEAM) activities and is based on the Maker Movement. After introducing the maker concept and explaining the rationale for adapting maker principles to fit into the university’s SALC, two facilitators who participated in Maker Conversation reflect on their experiences during the academic year. This paper highlights the successes of Maker Conversation for both students and facilitators, as well as the challenges that facilitators faced. Future plans that address these challenges are discussed. The facilitators felt that Maker Conversation provides valuable learning opportunities and plan to further develop and enhance the program for students and facilitators. This paper may benefit educators at other institutions who are interested in implementing their own version of Maker Conversation in their SALC.
Eosinophilic gastrointestinal disorders: new perspectives and the emerging role of biological therapies
Authors: Losa Francesca , Cingolani Arianna
Published: June 2023

The advent of biological drugs has opened up new therapeutic possibilities in the field of eosinophilic gastro-intestinal diseases (EGIDs). EGIDs are chronic inflammatory diseases of the gastrointestinal tract unrelated to drugs or infections, and eosinophilic esophagitis (EoE) is the most frequent form. EGIDs are complex disorders, which pathogenesis is still partially unknown. The diagnosis of EGIDs relies on the combination of different data, such as clinical manifestations, laboratory tests, endoscopic, and histological data. The gold standard at present is the histological examination obtained from biopsies under endoscopic guidance, but the diagnostic criteria for each disorder are still not fully defined, and few clinical scores are validated, for all these reasons, conducting clinical trials on EGIDs is challenging. The dietary approach remains currently a first-line treatment, despite its efficacy being influenced by patients’ compliance. Exclusion diets, nevertheless, involve potential nutritional deficiencies. Two of the pivotal pharmacological therapies for the treatment of EGIDs are proton pump inhibitors (PPIs), especially for EoE, and systemic or topical steroids. Long-term corticosteroid therapies are, however, associated with even severe side effects, so steroid-sparing therapies are needed to achieve the same results, in the last years monoclonal antibodies have been studied. To date, dupilumab is the only approved biological drug for EoE therapy, but many others are currently being tested in clinical trials also for the other forms of EGIDs. This work presents a complete review of the role of biological drugs in EGIDs to date, systematically structured by pathology.
Cannabinoid-based medicines in clinical care of chronic non-cancer pain: an analysis of pain mechanism and cannabinoid profile
Authors: Rapin Lucile , Arboleda Maria Fernanda , Prosk Erin , Su Charles , Watier Alain , Dworkind Michael
Published: June 2023

Aim: Among treatments for chronic non-cancer pain (CNCP), cannabinoid-based medicines (CBMs) have become extremely popular. Evidence remains modest and limited primarily to delta-9-tetrahydrocannabinol (THC) for neuropathic pain; nevertheless, the use of various CBMs, including cannabidiol (CBD) to treat neuropathic, nociceptive, and mixed pain has increased globally. This observational case-series assessed the impact of CBMs as a complementary treatment by pain mechanism and cannabinoid profile over three months.
Methods: An analysis of patients with CNCP and treated with CBMs who consented to an ongoing registry was performed. Outcomes were patient-reported such as the Edmonton symptom assessment system-revised, brief pain inventory-short form, and 36-item short form health survey. Data from patients with complete outcomes for baseline and 3-month follow-up was extracted. Characteristics of adverse drug reactions (ADRs), including a description of the suspected product were also assessed.
Results: A total of 495 patients were part of this analysis (mean age = 56 years old; 67% women). At 3-month, the proportional use of THC:CBD balanced and THC-dominant products increased. Patients with neuropathic pain had higher pain-severity scores vs. nociceptive pain. In addition to patients with neuropathic pain, patients with nociceptive and mixed pain also reported improvements in pain severity and secondary symptoms such as anxiety, depression, drowsiness, fatigue, sleep disturbances, and overall, health-related quality of life. THC-dominant treatment is more likely to be recommended when pain is severe, whereas CBD-dominant is favored for less severe cases. ADRs were more frequent among cannabis-naive patients and included dizziness, headache, and somnolence among others.
Conclusions: Findings suggest that CBMs can be effective for neuropathic as well as nociceptive and mixed pain. THC is more frequently recommended for neuropathic and severe pain. Future research on CBMs in pain management must include details of CBM composition, and pain mechanism and must consider potential ADRs.
Performance Analysis of Energy Efficiency and Security Solutions of Internet of Things Protocols
Authors: Itagi Manjunath , V Dankan Gowda , Prasad KDV , Kumar Pullela SVVSR , R Shekhar , Ashreetha B.
Published: June 2023

The scientific and business communities are showing considerable interest in wireless sensor networks (WSN). The availability of low-cost, small-scale components like CPUs, radios, and sensors, which are often combined into a single chip, is crucial. Parallel to the evolution of WSNs, the concepts of the IoT have been evolving in recent years. Wireless communication technologies may play a significant role in the implementation of IoT, despite the fact that IoT does not need or require any particular technology for communication. WSN assisted IoT networks can drive several applications in many industries. The proposed research explores the possibility of enhancing energy efficiency in WSN-assisted IoTN by balancing various challenging sensor network performance metrics. The base station's current placement inside the sensing field is predetermined by the preexisting routing algorithms. Our study examines the impact of base station placement outside and within the prescribed sensing domains on energy consumption and network longevity. In addition, methods for transferring data from the distributed source sensor to the base station while minimizing energy consumption are investigated. In this preliminary study, we focus on developing an algorithm for WSN-Assisted IoTN that can balance network factors such as hop count, communication distance, and residual energy. To further optimize the routing route between local cluster heads and the base station, a novel network architecture is built based on the Ant-optimization model, which uses centroid routing to balance energy consumption among local clusters. An open-source Network Simulator (NS-3) is used to model the behaviour of the proposed routing protocols and compare them to comparable existing network protocols. All of the suggested protocols have the same fundamentals for creating networks, however they vary in terms of routing, optimization, and performance depending on the development effort under consideration.
Social Mobility through Education: Lifelong Learning and the Roma-Minority in Selected Central and Eastern European Countries
Authors: Óhidy Andrea
Published: June 2023

Education plays a central role in supporting or impeding social mobility (Bourdieu & Passeron, 1974; Fend, 1980, 2006). The disadvantaged social and economic situation of the biggest part of the Roma minority (not only) in Central and Eastern Europe is usually seen as the main reason for their low educational attainment and success. And vice versa: the poor educational results are considered the main reason for their social deprivations. Therefore, education and lifelong learning have become the main strategy for improving their situation, especially since the ´Europeanization of the Roma issue` (Ram, 2015) through the European Union. Today, Education and lifelong learning are now the centre of EU-policies for achieving political and economic goals, like economic growth and social cohesion (Óhidy, 2008, 2009). This article analyzes the problems faced by and opportunities presented to the Roma people in selected Central and Eastern European countries, problems and opportunities arisen in the years up until 2020, regarding social mobility through education. In its analysis, this paper focused on the similarities. The article is based on 5 country studies from 2019, written by experts from the Czech Republic, Hungary, Poland, Romania and Slovakia (see Óhidy & Forray, 2019). The study uses the evidence from the country studies from Markéta Levínska, Dana Bittnerová & David Doubek, 2019 (Czech Republic), Julianna Boros & Eszter Gergye, 2019 (Hungary), Agnieszka Swietek & Wiktor Osuch, 2019 (Poland), Aurora Adina Colomeischi, 2019 (Romania) and Rastislav Rosinsky, 2019 (Slovakia) to explore the similarities in challenges, to increase the participation and success of Roma people.
Molecular mechanisms of thermoradiotherapy efficacy in cancer patients with metabolic disorders
Authors: Юнусова Наталья , Сваровский Дмитрий , Коновалов Артем , Сиденко Евгения , Старцева Жанна
Published: June 2023

Особый интерес вызывают исследования по применению дистанционной лучевой терапии или химиолучевой терапии в сочетании с локальной гипертермией, результаты которых свидетельствуют о повышении непосредственной эффективности лучевой терапии за счет выраженной регрессии опухоли, а также увеличении длительности безрецидивного периода для ряда локализаций. Молекулярные механизмы эффективности локальной гипертермии в составе комбинированного лечения у больных злокачественными новообразованиями с метаболическими нарушениями недостаточно изучены. Эти механизмы могут быть ассоциированы с изменениями на уровне клетки (особенности системы репарации ДНК в опухоли при ожирении; miRNA в опухоли, ассоциированные с терморадиорезистентностью на фоне ожирения; стволовые клетки в опухоли на фоне ожирения, циркулирующие опухолевые клетки), а также с внеклеточными факторами, которые в свою очередь можно разделить на растворимые компоненты биологических жидкостей (например, плазмы крови, асцитической жидкости) и внеклеточные везикулы. Проблемы при проведении терапии больных злокачественными новообразованиями с метаболическими нарушениями связаны с отсутствием клинических рекомендаций по использованию локальной гипертермии, с недостаточной разработанностью методических подходов (способов и техник нагрева, длительностью сеанса, необходимыми температурам и количеством процедур), а также с не изученностью факторов прогноза эффективности комбинированного лечения.
Exogenous expression of protein phosphatase DUSP9 reduces the rate of migration of kidney carcinoma cells
Authors: Якубович Елена , Полищук Анна , Eвтушенко Владимир
Published: June 2023

Поиск новых мишеней для терапевтического воздействия на метастатическую форму карциномы почки (КП) остается актуальной задачей на сегодняшний день. Одной из таких мишеней может быть протеинфосфатаза DUSP9. О значительном снижении уровня мРНК DUSP9 в клинических образцах КП по сравнению c нормальной тканью впервые сообщили Чебуркин с соавторами в 2002 году [1]. Позднее мы показали, что подавление экспрессии мРНК DUSP9 происходит уже на ранних стадиях заболевания. Мы также показали, что экспрессия гена DUSP9 при КП может регулироваться на эпигенетическом уровне и, кроме того, дифференциально, в зависимости от пола пациента. В последующие годы, онкосупрессорные свойства DUSP9 при КП были подтверждены другими исследователями.
Целью данной работы было изучение влияния экзогенной экспрессии гена DUSP9 на пролиферацию и миграцию клеток КП человека.
Материалы и методы. В работе использовалась DUSP9-негативная линия КП человека ACHN. Трансфекцию клеток проводили сконструированным нами DUSP9-экспрессирующим вектором. Эффективность трансфекции оценивали методами иммунофлуоресценции и вестерн-блота, количество жизнеспособных клеток MTT-тестом, скорость миграции клеток скрэтч-тестом. Внеклеточные везикулы из кондиционной среды выделяли, используя SubXTM технологию, и характеризовали методом анализа траекторий наночастиц и вестерн-блотом.
Результаты. Эффективность трансфекции варьировала от 70% до 90%. Количество жизнеспособных клеток, экспрессирующих DUSP9, и клеток, трансфицированных вектором без вставки, различалась незначительно 48 часов после трансфекции. Экспрессия DUSP9 статистически значимо уменьшала скорость миграции клеток по сравнению с контролем. Белок DUSP9 обнаруживался в экзосомной фракции бессывороточной кондиционной среды от клеток, трансфицированных DUSP9-экспрессирующим вектором.
Выводы. Мы показали, что экзогенная экспрессия DUSP9 замедляет миграцию клеток КП. Результат указывает на то, что одной из возможных ролей DUSP9 в канцерогенезе почки может быть регулирование процесса метастазирования.