bluuebunny/crossref_metadata_2025 huggingface dataset:
Do Only White or Asian Males Belong in Genius Organizations? How Academic Organizations’ Fixed Theories of Excellence Help or Hinder Different Student Groups’ Sense of Belonging
Authors: Bauer Christina , Hannover Bettina
Published: February 2021

High-profile organizations often emphasize fixed giftedness rather than malleable effort-based criteria as critical for excellent achievements. With giftedness being primarily associated with White or Asian males, such organizational implicit theories of excellence may shape individuals’ sense of belonging depending on the extent to which they match the gifted White/Asian male prototype, i.e., the prototypical gifted person which is typically imagined to be a White or Asian male. Previous research has reported fixed excellence theories emphasizing giftedness (vs. malleable theories emphasizing effort) to impair the sense of belonging of females and negatively stereotyped ethnic minorities. We investigate the combined effects of gender and ethnicity. We predicted that, while individuals whose gender and ethnicity do not match the gifted prototype show a reduced sense of belonging in fixed organizations, White/Asian males who match the gifted prototype show the opposite effect, experiencing a higher sense of belonging in fixed (vs. malleable) organizations. In an experimental study (N = 663 students), we manipulated advertising material used by a highly selective academic institution in Germany and tested effects on students’ belonging. Whereas the original material emphasized giftedness as essential for excelling (fixed excellence version), our manipulated version stressed effort (malleable version). As expected, females from stereotyped ethnic minority groups felt less belonging in the fixed (vs. malleable) organization, while White/Asian males anticipated stronger belonging in the fixed (vs. malleable) organization. Fixed views of excellence impair negatively stereotyped individuals’ belonging but may even strengthen the belonging of prototypical academic elites.
Unmet Needs and Classical Pitfalls in the Management of Adolescents With Behavioral Problems in Emergency
Authors: Guedj-Bourdiau Marie-Jeanne , Guilé Jean-Marc , Garny de la Rivière Sébastien , Pace Ugo , Cohen David , Benarous Xavier
Published: February 2021

While behavioral problems are the main reasons for adolescents to be referred to an emergency room for mental health problems, their clinical management remain usually heterogenous, poorly standardized, and associated with a low level of patient and family satisfaction. So far, most attention has been paid to the treatment of agitation, and few insights have been provided on the treatment plan of behavioral problems once the crisis is over and a psychiatric or medical condition ruled out. This perspective article represents an attempt to incorporate multiple theoretical approaches to provide a comprehensive and operational model for the management of adolescents with behavioral problems in an emergency department. Short hypothetical case vignettes illustrate the importance of considering several levels of analysis to understand the adolescent's problematic behavior which can be seen as a symptom of a medical/psychiatric condition (medical model), as a maladaptive strategy in a context of vulnerability (developmental model), and finally as a mode of communication in a context of ill-adapted relational patterns (systemic model). As behavioral problems in adolescence are a complex issue, frequently involving the intervention of professionals from various disciplines, being aware of such different levels of understanding could help to preclude any role confusion and to provide better targeted interventions.
From an Alternative Medicine to a New Treatment for Refractory Epilepsies: Can Cannabidiol Follow the Same Path to Treat Neuropsychiatric Disorders?
Authors: Bitencourt Rafael M. , Takahashi Reinaldo N. , Carlini Elisaldo A.
Published: February 2021

Although cannabis has been known for ages as an “alternative medicine” to provide relief from seizures, pain, anxiety, and inflammation, there had always been a limited scientific review to prove and establish its use in clinics. Early studies carried out by Carlini's group in Brazil suggested that cannabidiol (CBD), a non-psychotropic phytocannabinoid present in Cannabis sativa, has anticonvulsant properties in animal models and reduced seizure frequency in limited human trials. Over the past few years, the potential use of cannabis extract in refractory epilepsy, including childhood epilepsies such as Dravet's syndrome and Lennox-Gastaut Syndrome, has opened a new era of treating epileptic patients. Thus, a considerable number of pre-clinical and clinical studies have provided strong evidence that phytocannabinoids has anticonvulsant properties, as well as being promising in the treatment of different neuropsychiatric disorders, such as depression, anxiety, post-traumatic stress disorder (PTSD), addiction, neurodegenerative disorders and autism spectrum disorder (ASD). Given the advances of cannabinoids, especially CBD, in the treatment of epilepsy, would the same expectation regarding the treatment of other neuropsychiatric disorders be possible? The present review highlights some contributions from Brazilian researchers and other studies reported elsewhere on the history, pre-clinical and clinical data underlying the use of cannabinoids for the already widespread treatment of refractory epilepsies and the possibility of use in the treatment of some neuropsychiatric disorders.
Phylogenetic Characteristics of West Nile Virus Isolated From Culex modestus Mosquitoes in West Kazakhstan
Authors: Nurmakhanov Talgat , Sansyzbaev Yerlan , Atshabar Boris , Berlin Vladimir , Kobzhasarov Damir , Yeskhojayev Olzhas , Vilkova Anna , Ayazbayev Timur , Andryuchshenko Alexey , Bidashko Fyodor , Hay John , Shvetsov Alexandr
Published: February 2021

West Nile virus is widespread in southern Russia, where the fever appears annually. Since Western Kazakhstan borders on southern Russia, we examined mosquitoes in this region for the presence of West Nile virus. Virus was detected in a small proportion of Culex modestus mosquitoes (3/239 pools) and isolates are related to strains from Volgograd, Russia. A screen for West Nile virus IgG was conducted and ~5% of the local human population tested positive.
Workforce Mobilization From the National Institutes of Health for the Ministry of Health Malaysia: A COVID-19 Pandemic Response
Authors: Muhammad Nur Amir Abdul Rassip , Binti Amer Nordin Awatef , Lim Yin Cheng , Binti Ahmad Shauki Nor Izzah , Binti Ibrahim Nor Hayati
Published: February 2021

The COVID-19 pandemic that emerged in 2019 has inflicted numerous clinical and public health challenges worldwide. It was declared a public health emergency by the World Health Organization and activated response teams at almost all Malaysian healthcare facilities. Upon activation of the National Crisis Preparedness and Response Center in January 2020, the National Institutes of Health Malaysia established a COVID-19 operation room at the facility level to address the rise in COVID-19 infection cases each day. The National Institutes of Health COVID-19 operation room committee formed a workforce mobilization team for an effective and efficient mobilization system to fulfill requests received for human resource aid within the Ministry of Health Malaysia facilities. Selected personnel would be screened for health and availability before mobilization letters and logistics arrangements if necessary. The workforce from the National Institutes of Health, consisting of various job positions, were mobilized every week, with each deployment cycle lasting 2 weeks. A total of 128 personnel from the six institutes under the National Institutes of Health were mobilized: tasks included fever screening, active case detection, health management at quarantine centers, and management of dead bodies. A well-organized data management system with a centralized online system integration could allow more rapid deployment and answer some of the key questions in managing a similar pandemic in the future. With improving infected COVID-19 cases throughout the country, the National Institutes of Health COVID-19 operation room was effectively closed on June 15, 2020, following approval from the Deputy Director-General of Health.
Facilitating Understanding, Modeling and Simulation of Infectious Disease Epidemics in the Age of COVID-19
Authors: Rubin David M. , Achari Shamin , Carlson Craig S. , Letts Robyn F. R. , Pantanowitz Adam , Postema Michiel , Richards Xriz L. , Wigdorowitz Brian
Published: February 2021

Interest in the mathematical modeling of infectious diseases has increased due to the COVID-19 pandemic. However, many medical students do not have the required background in coding or mathematics to engage optimally in this approach. System dynamics is a methodology for implementing mathematical models as easy-to-understand stock-flow diagrams. Remarkably, creating stock-flow diagrams is the same process as creating the equivalent differential equations. Yet, its visual nature makes the process simple and intuitive. We demonstrate the simplicity of system dynamics by applying it to epidemic models including a model of COVID-19 mutation. We then discuss the ease with which far more complex models can be produced by implementing a model comprising eight differential equations of a Chikungunya epidemic from the literature. Finally, we discuss the learning environment in which the teaching of the epidemic modeling occurs. We advocate the widespread use of system dynamics to empower those who are engaged in infectious disease epidemiology, regardless of their mathematical background.
Case Report: Utilizing AI and NLP to Assist with Healthcare and Rehabilitation During the COVID-19 Pandemic
Authors: Carriere Jay , Shafi Hareem , Brehon Katelyn , Pohar Manhas Kiran , Churchill Katie , Ho Chester , Tavakoli Mahdi
Published: February 2021

The COVID-19 pandemic has profoundly affected healthcare systems and healthcare delivery worldwide. Policy makers are utilizing social distancing and isolation policies to reduce the risk of transmission and spread of COVID-19, while the research, development, and testing of antiviral treatments and vaccines are ongoing. As part of these isolation policies, in-person healthcare delivery has been reduced, or eliminated, to avoid the risk of COVID-19 infection in high-risk and vulnerable populations, particularly those with comorbidities. Clinicians, occupational therapists, and physiotherapists have traditionally relied on in-person diagnosis and treatment of acute and chronic musculoskeletal (MSK) and neurological conditions and illnesses. The assessment and rehabilitation of persons with acute and chronic conditions has, therefore, been particularly impacted during the pandemic. This article presents a perspective on how Artificial Intelligence and Machine Learning (AI/ML) technologies, such as Natural Language Processing (NLP), can be used to assist with assessment and rehabilitation for acute and chronic conditions.
Increased Abundance of Tumour-Associated Neutrophils in HPV-Negative Compared to HPV-Positive Oropharyngeal Squamous Cell Carcinoma Is Mediated by IL-1R Signalling
Authors: Al-Sahaf Sarmad , Hendawi Naeima B. , Ollington Bethany , Bolt Robert , Ottewell Penelope D. , Hunter Keith D. , Murdoch Craig
Published: February 2021

The incidence of human papillomavirus (HPV)-associated cancer is increasing and HPV is now implicated in the aetiology of more than 60% of all oropharyngeal squamous cell carcinomas (OPSCC). In OPSCC, innate immune cells such as neutrophils and macrophages generally correlate with poor prognosis, whilst adaptive immune cells, such as lymphocytes, tend to correlate with improved prognosis. This may, in part, be due to differences in the immune response within the tumour microenvironment leading to the recruitment of specific tumour-associated leukocyte sub-populations. In this study, we aimed to examine if differences exist in the levels of infiltrated leukocyte sub-populations, with particular emphasis on tumour-associated neutrophils (TAN), and to determine the mechanism of chemokine-induced leukocyte recruitment in HPV-positive compared to HPV-negative OPSCC. Immunohistochemical analysis showed that HPV-negative OPSCC contained significantly more neutrophils than HPV-positive tumours, whilst levels of CD68+ macrophages and CD3+ lymphocytes were similar. Using a 3D tissue culture model to represent tumour-stromal interactions, we demonstrated that HPV-negative tumour-stromal co-cultures expressed significantly higher levels of CXCL8, leading to increased neutrophil recruitment compared to their HPV-positive counterparts. HPV-negative OPSCC cells have previously been shown to express higher levels of IL-1 than their HPV-positive counterparts, indicating that this cytokine may be responsible for driving increased chemokine production in the HPV-negative 3D model. Inhibition of IL-1R in the tumour-stromal models using the receptor-specific antagonist, anakinra, dramatically reduced chemokine secretion and significantly impaired neutrophil and monocyte recruitment, suggesting that this tumour-stromal response is mediated by the IL-1/IL-1R axis. Here, we identify a mechanism by which HPV-negative OPSCC may recruit more TAN than HPV-positive OPSCC. Since TAN are associated with poor prognosis in OPSCC, our study identifies potential therapeutic targets aimed at redressing the chemokine imbalance to reduce innate immune cell infiltration with the aim of improving patient outcome.
“He Never Wants to Leave. I Would Leave in a Second.” Examining Perceptions of Rural Life and its Impact on Families who Migrate for Employment and Those who Stay Behind in Atlantic Canadian Communities
Authors: Murray Christina , Skelding Hannah S. , Lionais Doug
Published: February 2021

In Canada, interprovincial labor migration is a common form of mobile work that is significant for rural communities especially in Atlantic Canada. Unique to this form of labor migration is the gendered nature of the phenomenon resulting in men often leaving their wives, families and rural communities behind for employment opportunities in the oil and gas sectors thousands of kilometers away. As men leave their families and communities for employment, women who are left behind become primary caregivers to children in addition to also being the primary caretakers of the family home. The Tale of Two Islands project was a multi-year, cross regional mixed methods research study that examined labor mobility and its impact on families and communities. This paper examines how labor migration has impacted families and rural communities. Drawing upon focus group, conversational and key informant interviews with families impacted by mobile labor and practitioners who serve them, societal perceptions of gendered norms and perceptions of rural life became illuminated. This has contributed to multiple contradictions and role confusion as families adapt and adjust to periods of reunification and separation while striving to remain connected to their rural communities. Men yearn for opportunities to be an active member of their home communities but cannot a result of living away for extended periods of time. In contrast, women who stay behind in rural communities often chose to isolate from community activities as a result of perceived judgments that are attributed to traditional views of rural life and family roles.
Radio Astronomical Tools for the Study of Solar Energetic Particles I. Correlations and Diagnostics of Impulsive Acceleration and Particle Propagation
Authors: Klein Karl-Ludwig
Published: February 2021

Solar energetic particles (SEPs) are sporadically ejected from the Sun during flares and coronal mass ejections. They are of major astrophysical interest, because the proximity of the Sun allows for detailed multi-messenger studies. They affect space weather due to interactions with electronics, with the Earth’s atmosphere, and with humans if they leave the protective shield of the magnetosphere of the Earth. Since early studies in the 1950s, starting with particle detectors on the ground, SEP events have been related to radio bursts. Two subjects are addressed in this chapter: attempts to establish quantitative correlations between SEPs and microwave bursts produced by gyro synchrotron radiation of mildly relativistic electrons, and the information derived from type III radio bursts on impulsive processes of particle acceleration and the coronal and interplanetary propagation. Type III radio bursts produced by electron beams on open magnetic field lines have a wide range of applications, including the identification of acceleration regions, the identification of confined particle acceleration with coronal signatures, but no SEPs, and the paths that the electrons, and energetic charged particles in general, take to travel from the low corona to the Heliosphere in case they escape. Simple scenarios of coronal particle acceleration are confirmed in relatively simple and short events. But the comparison with particle transport models shows that longer and delayed acceleration episodes exist especially in large SEP events. They will be discussed in a companion chapter.
Aerobic, Resistance, and Combination Training on Health-Related Quality of Life: The STRRIDE-AT/RT Randomized Trial
Authors: Collins Katherine A. , Fos Liezl B. , Ross Leanna M. , Slentz Cris A. , Davis Paul G. , Willis Leslie H. , Piner Lucy W. , Bateman Lori A. , Houmard Joseph A. , Kraus William E.
Published: February 2021

Purpose: The main purpose of this study was to determine the differential effects of aerobic training (AT), resistance training (RT), and a combination of aerobic and resistance training (AT/RT) on changes in self-rated HrQoL measures, including the Short-Form 36 (SF-36) survey and Satisfaction with Physical Function and Appearance survey. We also sought to determine if combination training (AT/RT) has a more or less additive effect compared to AT or RT alone on self-rated HrQoL measures.

Materials and Methods: Participants (n = 137) completed one of three 8-month exercise interventions: (1) AT: 14 kcal exercise expenditure per kg of body weight per week (KKW; equivalent to roughly 12 miles/week) at 65–80% of peak oxygen consumption; (2) RT: 3 days per week, 8 exercises, 3 sets per exercise, 8–12 repetitions per set; (3) AT/RT: full combination of the AT and RT interventions. The SF-36 survey, Satisfaction with Physical Function and Appearance survey, physical fitness, and anthropometrics were assessed at baseline and post-intervention. Paired t-tests determined significant pre- vs. post-intervention scores within groups (p < 0.05). Analyses of covariance determined differences in change scores among groups (p < 0.05).

Results: On average, participants were 49.0 ± 10.6 years old, obese (BMI: 30.6 ± 3.2 kg/m2), female (57.7%), and Caucasian (84.7%). Following the 8-month intervention, exercise groups improved peak VO2 (all groups), strength (RT and AT/RT), and anthropometric measures (AT and AT/RT). For the SF-36, RT (p = 0.03) and AT/RT (p < 0.001) significantly improved their physical component score; only AT/RT (p < 0.001) significantly improved their mental component score. Notably, all groups significantly improved both their satisfaction with physical function and appearance scores (All Groups: p < 0.001 for both outcomes).

Conclusions: We found that aerobic, resistance, or combination exercise training improves several components of self-rated HrQoL, including physical function, appearance, and mental well-being.

Clinical Trial Registration: No. NCT00275145.
Movement Patterns and Match Statistics in the National Rugby League Women's (NRLW) Premiership
Authors: Newans Tim , Bellinger Phillip , Buxton Simon , Quinn Karlee , Minahan Clare
Published: February 2021

As women's rugby league grows, the need for understanding the movement patterns of the sport is essential for coaches and sports scientists. The aims of the present study were to quantify the position-specific demographics, technical match statistics, and movement patterns of the National Rugby League Women's (NRLW) Premiership and to identify whether there was a change in the intensity of play as a function of game time played. A retrospective observational study was conducted utilizing global positioning system, demographic, and match statistics collected from 117 players from all NRLW clubs across the full 2018 and 2019 seasons and were compared between the ten positions using generalized linear mixed models. The GPS data were separated into absolute (i.e., total distance, high-speed running distance, and acceleration load) and relative movement patterns (i.e., mean speed, mean high speed (> 12 km·h−1), and mean acceleration). For absolute external outputs, fullbacks covered the greatest distance (5,504 m), greatest high-speed distance (1,081 m), and most ball-carry meters (97 m), while five-eighths recorded the greatest acceleration load (1,697 m·s−2). For relative external outputs, there were no significant differences in mean speed and mean high speed between positions, while mean acceleration only significantly differed between wingers and interchanges. Only interchange players significantly decreased in mean speed as their number of minutes played increased. By understanding the load of NRLW matches, coaches, high-performance staff, and players can better prepare as the NRLW Premiership expands. These movement patterns and match statistics of NRLW matches can lay the foundation for future research as women's rugby league expands. Similarly, coaches, high-performance staff, and players can also refine conditioning practices with a greater understanding of the external output of NRLW players.
Warm-Ups and Coaches' Perceptions: Searching for Clues to Improve Injury Prevention in Youth Basketball
Authors: Räisänen Anu M. , Owoeye Oluwatoyosi B. A. , Befus Kimberley , van den Berg Carla , Pasanen Kati , Emery Carolyn A.
Published: February 2021

Introduction: Regular use of neuromuscular training (NMT) warm-up programs improves performance and prevents injuries. However, low level of adoption of these programs remains a problem. Understanding the current warm-ups in youth basketball and coaches' perceptions on injury prevention can guide the design of superior implementation strategies. This study describes warm-ups in youth basketball and coaches' injury prevention-related knowledge, attitudes, beliefs, and information sources.

Methods: Youth basketball coaches (n = 50) completed a preseason questionnaire. The questionnaire covered warm-up length, use of aerobic/agility/balance/strength/other exercises in the warm-up, injury-related knowledge, attitudes, beliefs, and sources of information.

Results: Typical warm-up duration was ≤ 10 min (48.0% of coaches, 95% CI: ±13.8%). All coaches included aerobic exercises in their warm-up. Agility, strength, and balance exercises were utilized by 80.0% (95% CI: ±11.7%), 70.7% (95% CI: ±13.6%), and 26.8% (95% CI: ±13.6%) of coaches, respectively. Most coaches agreed to some extent that basketball injuries are preventable (94%) and that participating in a NMT warm-up program would reduce player's risk of injury (92%). Other coaches were identified as the most common source of information on warm-ups and injury prevention.

Discussion: Coaches use parts of effective NMT warm-up programs, but balance exercises are not well adopted. Considering the level of evidence supporting the importance of balance exercises in injury prevention, it is crucial to improve the implementation of NMT warm-up programs in youth basketball, for example, through educational courses. As fellow coaches were identified as the most important source of information, coaches' role in knowledge translation should be emphasized.
Case Report: Adjusting Seat and Backrest Angle Improves Performance in an Elite Paralympic Rower
Authors: Severin Anna Cecilia , Danielsen Jørgen , Falck Erichsen Jørgen , Wold Eikevåg Sindre , Steinert Martin , Ettema Gertjan , Baumgart Julia Kathrin
Published: February 2021

Paralympic rowers with functional impairments of the legs and trunk rely on appropriate seat configurations for performance. We compared performance, physiology, and biomechanics of an elite Paralympic rower competing in the PR1 class during ergometer rowing in a seat with three different seat and backrest inclination configurations. Unlike able-bodied rowers, PR1 rowers are required to use a seat with a backrest. For this study, we examined the following seat/backrest configurations: conA: 7.5°/25°, conB: 0°/25°, and conC: 0°/5° (usually used by the participant). All data was collected on a single day, i.e., in each configuration, one 4-min submaximal (100 W) and one maximal (all-out) stage was performed. The rowing ergometer provided the average power and (virtual) distance of each stage, while motion capture provided kinematic data, a load cell measured the force exerted on the ergometer chain, and an ergospirometer measured oxygen uptake (V˙O2). Where appropriate, a Friedman's test with post-hoc comparisons performed with Wilcoxon signed-ranked tests identified differences between the configurations. Despite similar distances covered during the submaximal intensity (conA: 793, conB: 793, conC: 787 m), the peak force was lower in conC (conA: 509, conB: 458, conC: 312 N) while the stroke rate (conA: 27 conB: 31, conC: 49 strokes·min−1) and V˙O2 (conA: 34.4, conB: 35.4, conC: 39.6 mL·kg−1·min−1) were higher. During the maximal stage, the virtual distances were 7–9% longer in conA and conB, with higher peak forces (conA: 934 m, 408 N, conB: 918 m, 418 N, conC: 856 m, 331 N), and lower stroke rates (conA: 51, conB: 54, conC: 56 strokes·min−1), though there was no difference in V˙O2peak (~47 ml−1·kg−1·min−1). At both intensities, trunk range of motion was significantly larger in configurations conA and conB. Although fatigue may have accumulated during the test day, this study showed that a more inclined seat and backrest during ergometer rowing improved the performance of a successful Paralympic PR1 rower. The considerable increase in ergometer rowing performance in one of the top Paralympic rowers in the world is astonishing and highlights the importance of designing equipment that can be adjusted to match the individual needs of Paralympic athletes.
Water Management in Agricultural Production, the Economy, and Venezuelan Society
Authors: Moreno-Pizani Maria Alejandra
Published: February 2021

The availability of water resources has a direct impact on the economy of a country and the development of the main production processes, from agriculture, irrigation, and food production, to energy generation and water supply. The regional economic and social development is influenced by an adequate management of water resources because it stimulates the economy by expanding and ability to provide water for multiple uses, directly impacting on the generation of employment the improving the quality of life of the population. Venezuela has abundant surface water resources in the large basins. The northern part of Venezuela, where the highest percentage of the population and the main economic activities are based, face a severe water scarcity. Irrigation systems under public sector administration are characterized by large budgetary restrictions, with works for rehabilitation, operation, and maintenance generally carried out with inefficient results, due to lack of adequate technical supervision. There is a gap of official information that allows highlight the crisis that the agricultural sector has faced in the last decade. Another, very important aspect is Venezuela's severe energy crisis which began to present a deficit of electric power generation that has been alarmingly evident since 2009, which has worsened for more than a decade, causing the lack of electricity supply in large regions of the country for periods of time exceeding 100 h, contributing to aggravate the country's economic crisis. Due to the situation described, Venezuelan food systems have been seriously affected mainly by the advanced deterioration of irrigation infrastructure and the water availability on production processes. This paper explores and analyses the influence of water management on production Venezuelan economics and society, focus in three pillars representing the qualitative and quantitative relationships of water management and its impact on the system considering the aspects related to the sustainability of Venezuelan agri-food systems, analyzing the fundamental aspects for food production, main indicators related to the national economy, addressing the challenges to ensure food security.
Public Attitudes and Willingness to Pay for Cultured Meat: A Cross-Sectional Experimental Study
Authors: Kantor Bella Nichole , Kantor Jonathan
Published: February 2021

Previous research has suggested that the general public is divided over their willingness to consider consuming cultured meat (CM) products. As commercial backing for cultured meat startups increases and the public interest in the US, Europe, and developing countries expands, formally evaluating attitudes to these products will become increasingly important. Willingness to pay (WTP) may provide insight into the level of acceptability of CM products, highlight latent societal preferences, and suggest commercial opportunities. To date, no studies have evaluated the societal WTP for CM products. A cross-sectional internet-based survey was distributed to 300 respondents in the US general population using a survey panel design. The mean age was 30 (range: 18–76), and 47% of respondents were male. We presented respondents with a series of scenarios relating to CM products, framing CM burgers as environmentally friendly vs. as a better alternative to traditional burgers. Prior research has highlighted taste and price as areas of societal concern, but no studies have rigorously evaluated the intersection between these considerations. When CM products were framed as being equivalent in taste to conventional meat, and where their environmental benefits were stressed, respondents were willing to pay significantly more than for a traditional burger ($2.11 vs. $1.00). This WTP jumped to $2.66 when framing the CM burger as the best burger, reflecting a 266% premium that consumers were willing to pay for an appropriately framed CM burger. Framing CM burgers as a better alternative to traditional burgers, rather than focusing on their environmental impact, similarly led to the highest desirability ratings. These preferences were also reflected in a contingent valuation discrete choice experiment examining preferences for paying $1 for a traditional burger vs. $2 for a CM burger. These findings support our hypothesis regarding the existence of what we term the gold-standard bias, a cognitive bias that systematically favors a product or service framed as the best available choice over and above its marginal benefit, and has significant and broad implications for feasibility, pricing, and marketing, suggesting the need for further research in this area.
Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies
Authors: Ji Lijiang , Zhang Yang , Xu Liang , Wei Jun , Weng Liping , Jiang Jie
Published: February 2021

Anal fistula, with its complicated pathogenesis, has been considered as a clinical challenge for centuries. The risk of frequent recurrence and incontinence constitutes a considerable threat in the long-term treatment of anal fistula. In this work, we narratively reviewed the scientific literature of new techniques that have been used for anal fistula treatment over the recent 5 years, objectively evaluated the pros and cons of each technique on the basis of clinical outcomes, and tried to disclose the effective strategies for anal fistula treatment. Up to date, surgery is the main method used for treating anal fistula, but there is no simple technique that can completely heal complex anal fistula. In the course of surgery treatment, the healing outcome, and the protection of anal function should be weighed comprehensively. Among the innovative techniques that have emerged in recent years, combined techniques based on drainage Seton and LIFT-plug seem to be the relatively effective therapies, but their effectiveness requires more multi-center prospective randomized controlled trials with large sample size and long-term follow-up to be validated.
Do Poor Functional Outcomes and Higher Morbidity Following Emergency Repair of Giant Hiatus Hernia Warrant Elective Surgery in Asymptomatic Patients?
Authors: Bujoreanu Iulia , Abrar Daniya , Lampridis Savvas , Date Ravindra
Published: February 2021

Background: Patients with a giant hiatus hernia may present with acute symptoms caused by obstruction, strangulation, perforation and uncontrolled bleeding. Emergency surgical repair has been associated with significant mortality and even greater morbidity. The aim of this study is to investigate the short-term outcomes following emergency repair of giant hiatus hernias.

Methods: Data were retrospectively collected for all patients who underwent emergency surgical repair of giant hiatus hernia in a university teaching hospital between 2009 and 2019. Outcomes were short-term morbidity and mortality. We also assessed the association of clinical predictor covariates, including age, ASA class and time to surgery, with risk for major morbidity.

Results: Thirty-seven patients with a median age of 68 years were identified. Following surgery, 9 patients (24.3%) developed organ dysfunction that required admission to the intensive care unit. Two patients (5.4%) underwent revision surgery and 3 (8.1%) developed pneumothorax that necessitated chest drain insertion. The commonest complication was pneumonia, which occurred in 13 patients (35.1%). Two deaths (5.4%) occurred within 30 days from surgery.

Conclusions: Emergency repair of giant hiatus hernia is associated with high rates of major morbidity, which includes poor functional status, further interventions, repeat surgery, and admission to the intensive care unit. Larger studies are warranted for long-term follow-up to assess post-operative quality of life is needed for asymptomatic patients and for those undergoing emergency surgery.
Astrovirus Outbreak in an Animal Shelter Associated With Feline Vomiting
Authors: Li Yanpeng , Gordon Emilia , Idle Amanda , Hui Alvin , Chan Roxanne , Seguin M. Alexis , Delwart Eric
Published: February 2021

An outbreak of cat vomiting was observed in an animal shelter. Testing for known enteric feline pathogens did not identify a causative agent. Viral metagenomics on four mini pools of feces from cases and controls housed in the same area revealed the presence of feline astrovirus in all pools. Also found with fewer reads in one pool each were rotavirus I, carnivore bocaparvovirus 3, norovirus (NoV) GVI, and a novel dependovirus. The genome of the highly prevalent astrovirus was sequenced and classified into mamastrovirus species two, also known as feline astrovirus. Real-time RT-PCR on longitudinally acquired fecal samples from 11 sick cases showed 10 (91%) to be shedding astrovirus for as long as 19 days. Affected cats were sick for an average of 9.8 days, with a median of 2.5 days (range = 1–31 days). Unaffected control cats housed in the same areas during the outbreak showed five out of nine (56%) to also be shedding astrovirus. Feline fecal samples collected from the same animal shelter ~1 year before (n= 8) and after (n= 10) showed none to be shedding astrovirus, indicating that this virus was temporarily associated with the vomiting outbreak and is not part of the commensal virome for cats in this shelter. Together with the absence of highly prevalent known pathogens, our results support a role for feline astrovirus infection, as well as significant asymptomatic shedding, in an outbreak of contagious feline vomiting.
Intestinal Health of Pigs Upon Weaning: Challenges and Nutritional Intervention
Authors: Zheng Lan , Duarte Marcos Elias , Sevarolli Loftus Ana , Kim Sung Woo
Published: February 2021

The primary goal of nursery pig management is making a smooth weaning transition to minimize weaning associated depressed growth and diseases. Weaning causes morphological and functional changes of the small intestine of pigs, where most of the nutrients are being digested and absorbed. While various stressors induce post-weaning growth depression, the abrupt change from milk to solid feed is one of the most apparent challenges to pigs. Feeding functional feed additives may be viable solutions to promote the growth of nursery pigs by enhancing nutrient digestion, intestinal morphology, immune status, and by restoring intestinal balance. The aim of this review was to provide available scientific information on the roles of functional feed additives in enhancing intestinal health and growth during nursery phase. Among many potential functional feed additives, the palatability of the ingredient and the optimum supplemental level are varied, and these should be considered when applying into nursery pig diets. Considering different stressors pigs deal with in the post-weaning period, research on nutritional intervention using a single feed additive or a combination of different additives that can enhance feed intake, increase weight gain, and reduce mortality and morbidity are needed to provide viable solutions for pig producers. Further research in relation to the feed palatability, supplemental level, as well as interactions between different ingredients are needed.
Pelleting of a Total Mixed Ration Affects Growth Performance of Fattening Lambs
Authors: Li Bo , Sun Xuezhao , Huo Qin , Zhang Guiguo , Wu Tingting , You Peihua , He Yuhua , Tian Wannian , Li Rongquan , Li Changsheng , Li Jianping , Wang Chunqing , Song Baijun
Published: February 2021

Feeding pelleted total mixed rations (TMR) instead of traditional loose concentrate plus forage to fattening lambs is an emerging practice. This study aimed to determine the effects of feeding pelleted TMR to fattening lambs on feed intake behaviour, growth performance, feed digestion, rumen fermentation characteristics, rumen microbial community, serum parameters, slaughter performance, meat quality, and the economic outcome. Two physical forms (pelleted vs. un-pelleted) of TMR composed of the same ingredients with the same particle sizes were compared in three animal experiments. Feed intake and average daily gain were higher when the TMR was pelleted, but apparent total tract digestibility of nutrients (organic matter, crude protein, neutral detergent fibre, acid detergent fibre, and ether extract) and serum parameters were not affected and apparent total tract dry matter digestibility was slightly lower. Feeding pelleted TMR increased total short-chain fatty acid concentration and decreased rumen pH. Rumen microbial community was not affected by the physical form of the TMR at phylum level but changed slightly at genus level. Liveweight at slaughter and hot carcass weight were higher for lambs fed the pelleted compared to the un-pelleted TMR, while dressing percentage and meat quality were not affected. In conclusion, feeding pelleted TMR improves growth performance of fattening lambs mainly due to an increase in feed intake. Feeding pelleted TMR is a feasible strategy for intensive lamb fattening operations.
Parasites of Native and Invasive Rodents in Chile: Ecological and Human Health Needs
Authors: Landaeta-Aqueveque Carlos , Moreno Salas Lucila , Henríquez AnaLía , Silva-de la Fuente María C. , González-Acuña Daniel
Published: February 2021

Invasive populations are a threat to biodiversity, resulting in the loss of species, and also a threat to human health, participating in the reservoir of diseases. Rodents are among the most important invasive species worldwide. Chile is a country that features island conditions in terms of geography and has been widely invaded by allochthonous rodents. In this mini-review, we updated the literature on macro-parasites infecting both native and invasive rodents and of vector-borne pathogens in continental Chile in order to assess the relative importance of invasive rodents from both ecological and public health points of view. A total of 174 parasite species were found, withSiphonapterarepresenting the most diverse group. When examining how parasites are shared between native and introduced rodents, the analysis suggests that parasites circulate freely within recipient populations, and are not significantly transmitted from source populations. Further, generalist parasites are typically more prone to being shared between native and introduced rodents. Most zoonotic parasites were reported in invasive rodents, suggesting that these rodents must represent a public health concern. Although several vector-borne pathogens have been reported in rodents or ectoparasites, most of the recently emerging research has illustrated that there is a lack of evidence on rodent–vector-borne zoonoses in most pathogens.
Climate Impact Mitigation Potential of European Air Traffic in a Weather Situation with Strong Contrail Formation
Authors: Lührs Benjamin , Linke Florian , Matthes Sigrun , Grewe Volker , Yin Feijia
Published: February 2021

Air traffic contributes to anthropogenic global warming by about 5% due to CO2 emissions and non-CO2 effects, which are primarily caused by the emission of NOx and water vapor as well as the formation of contrails. Since—in the long term—the aviation industry is expected to maintain its trend to grow, mitigation measures are required to counteract its negative effects upon the environment. One of the promising operational mitigation measures that has been a subject of the EU project ATM4E is climate-optimized flight planning by considering algorithmic climate change functions that allow for the quantification of aviation-induced climate impact based on the emission’s location and time. Here, we describe the methodology developed for the use of algorithmic climate change functions in trajectory optimization and present the results of its application to the planning of about 13,000 intra-European flights on one specific day with strong contrail formation over Europe. The optimization problem is formulated as bi-objective continuous optimal control problem with climate impact and fuel burn being the two objectives. Results on an individual flight basis indicate that there are three major classes of different routes that are characterized by different shapes of the corresponding Pareto fronts representing the relationship between climate impact reduction and fuel burn increase. On average, for the investigated weather situation and traffic scenario, a climate impact reduction in the order of 50% can be achieved by accepting 0.75% of additional fuel burn. Higher mitigation gains would only be available at much higher fuel penalties, e.g., a climate impact reduction of 76% associated with a fuel penalty of 12.8%. However, these solutions represent much less efficient climate impact mitigation options.
Average Degree of Coverage and Coverage Unevenness Coefficient as Parameters for Spraying Quality Assessment
Authors: Cieniawska Beata , Pentos Katarzyna
Published: February 2021

The purpose of the research was to determine the influence of selected factors on the average degree of coverage and uniformity of liquid spray coverage using selected single and dual flat fan nozzles. The impact of nozzle type, spray pressure, driving speed, and spray angle on the average degree of coverage and coverage unevenness coefficient were studied. The research was conducted with special spray track machinery designed and constructed to control and change the boom height, spray angle, driving speed, and spray pressure. Based on the research results, it was found that the highest average coverage was obtained for single standard flat fan nozzles and dual anti-drift flat fan nozzles. At the same time, the highest values of unevenness were observed for these nozzles. Inverse relationships were obtained for air-induction nozzles. Maximization of coverage with simultaneous minimization of unevenness can be achieved by using a medium droplet size for single flat fan nozzles (volume median diameter (VMD) = 300 μm) and coarse droplet size for dual flat fan nozzles (VMD = 352 μm), with low driving speed (respectively 1.1 m∙s−1 and 1.6 m∙s−1) and angling of the nozzle by 20° in the opposite direction to the direction of travel.
The Effect of Fertilization with Spent Mushroom Substrate and Traditional Methods of Fertilization of Common Thyme (Thymus vulgaris L.) on Yield Quality and Antioxidant Properties of Herbal Material
Authors: Kwiatkowski Cezary A. , Harasim Elżbieta
Published: February 2021

This experiment was designed to determine the effect of spent mushroom substrate, farmyard manure, and mineral fertilization with nitrogen, phosphorus, and potassium on the yield and quality of raw material obtained from two cultivars (“Słoneczko” and “De Dolj”) of common thyme. Unfertilized plots with thyme crops were included as the control treatment. Different row spacings (30 cm and 40 cm) represented the second experimental factor. The highest total yield of thyme raw material was found in the treatment with mineral NPK fertilization, but also in the treatments where spent mushroom substrate (SMS) and mineral NPK fertilization were applied at a ratio of 50:50%. Fertilization with SMS alone (100%) yielded smaller production effects, but they were higher than in the case of fertilization with manure. The high suitability of spent mushroom substrate applied alone or supplemented with mineral fertilization at different rates in spring was confirmed by the best quality parameters and antioxidant properties of the raw material. The use of a wider row spacing (40 cm) resulted in a higher yield of thyme raw material than in the case of a narrower one (30 cm). The narrower row spacing significantly positively affected some of the analyzed quality parameters of the harvested raw material, such as: essential oil content, polyphenol content, and antioxidant activity. The thyme cultivar “Słoneczko” proved to be absolutely more beneficial in terms of yield quantity and quality than the foreign cultivar “De Dolj”.
Examining Alternatives to Painful Piglet Castration Within the Contexts of Markets and Stakeholders: A Comparison of Four EU Countries
Authors: Lin-Schilstra Li , Ingenbleek Paul T.M.
Published: February 2021

To avoid the occurrence of boar taint in pork, the castration of piglets without pain relief is a common practice in many European countries. The public has been calling for more animal-friendly alternatives, which include anesthesia/analgesia, immunocastration, and the raising of entire males. To prevent potential trade barriers, the European Commission was initially more in favour of a single method. To date, however, only six countries have passed laws banning castration, and the pig farmers in these countries have chosen different alternatives. To understand the reasons behind the continuing fragmentation, this study examines the issue of castration within the context of four national pork production systems: in the Netherlands, France, Slovenia, and Germany. Drawing on in-depth qualitative data, the study demonstrates that stakeholders are generally willing to abandon the practice of piglet castration without anesthesia/analgesia. Their preferences for alternatives are largely dependent on contextual factors, however, including the structure, scale, and cost and quality orientation of the production system. The results imply that, although a single solution for castration is unlikely to evolve amongst the diverse pork-production systems in Europe, a future without the painful castration of piglets is possible if alternatives are accepted to coexist.