bluuebunny/crossref_metadata_2025 huggingface dataset:
Escolha da contracepção hormonal por mulheres assistidas na atenção primária: fatores limitantes e medo
Authors: Monçalves Kelvin Leandro Marques , Wilhelm Laís Antunes , Silveira Andressa da , Ferreira Carla Lizandra de Lima , Silva Silvana Cruz da , Soliz Paola Piovenzano de , Soccol Keity Laís Siepmann
Published: July 2023

Objetivo: Conhecer como ocorre a escolha pela contracepção hormonal por mulheres assistidas na Atenção Primária à Saúde. Método: Estudo qualitativo, descritivo e exploratório realizado em uma Estratégia Saúde da Família na região central do Rio Grande do Sul entre os meses de janeiro a março de 2022. Participaram 20 mulheres entre 18-43 anos. A produção de dados ocorreu mediante entrevista composta por questões abertas, as enunciações foram transcritas e submetidas à análise temática. Resultados: As participantes revelaram a falta de opção fornecida pelo Sistema Único de Saúde na escolha da contracepção hormonal, bem como apresentam fatores limitantes como dúvidas, dificuldades e medo ao utilizar o anticoncepcional hormonal devido à falta de orientação profissional na Atenção Primária à Saúde. Conclusão: A escolha do método contraceptivo precisa levar em consideração a autonomia da mulher e os profissionais de saúde que atuam na Atenção Primária à Saúde devem garantir o direito de escolha, minimizar as dúvidas, medos e tabus que circundam o processo de anticoncepção hormonal. Ademais, as consultas de saúde da mulher devem oportunizar a educação em saúde, o diálogo e a troca de saberes.
Estimativa do risco de doenças cardiovasculares entre adultos indígenas da etnia Krenak, Minas Gerais, Brasil
Authors: Chagas Cristiane Alvarenga , Sá Ricardo Américo Ribeiro de , Castro Teresa Gontijo de , Miranda Aline Elizabeth da Silva , Leite Maurício Soares , Pimenta Adriano Marçal
Published: July 2023

Objetivo: estimar o risco de doenças cardiovasculares em indígenas Krenak por meio do Escore de Risco Cardiovascular de Framingham. Metodologia: estudo epidemiológico transversal realizado com indígenas de 30 a 74 anos, em Terra Indígena localizada na região leste de Minas Gerais, Brasil. Os dados coletados foram: peso e altura para cálculo do IMC, aferição da pressão arterial e glicemia capilar casual, sexo, idade e tabagismo. O risco cardiovascular estimado em 10 anos foi calculado a partir do algoritmo de Escore de Framingham. Além disso, foram calculados o risco cardiovascular normal, o risco cardiovascular ótimo e a idade cardiovascular. A amostra foi caracterizada com a apresentação das frequências absolutas e relativas das variáveis que compõem o escore de risco cardiovascular de Framingham, estratificada pelo sexo. Resultados: observou-se que o risco cardiovascular em 10 anos entre os indígenas Krenak foi superior ao risco normal, bem como a idade cardiovascular foi maior que a idade cronológica, apesar da maioria da amostra ter apresentado um baixo risco cardiovascular em 10 anos, sem diferença estatística entre os sexos. Conclusão: apesar da predominância de baixo risco cardiovascular em 10 anos entre os indígenas Krenak, o resultado da idade cardiovascular superior à idade cronológica pode ocasionar morbimortalidade por doenças cardiovasculares ao longo do tempo nessa população.
Concordância às medidas de flexibilização durante a pandemia de covid-19 no Brasil
Authors: Dos Santos Silva Ruan Víctor , Sávio Dias Moura Heriederson , Mendes Delpino Felipe , César do Nascimento Murilo , Carlos Vieira Ramos Antônio , Zamboni Berra Thaís , Soares Tenório de Araújo Juliana , Alexandre Arcêncio Ricardo
Published: July 2023

Objetivo: analisar os fatores associados à concordância com a flexibilização das medidas de proteção no Brasil durante a pandemia pela COVID-19. Método: estudo transversal, com dados de uma web survey realizada com adultos residentes no Brasil, entre agosto de 2020 e fevereiro de 2021. Resultados: dos 1.516 respondentes, a maioria possuía idade entre 40 a 59 anos (38,8%), sexo feminino (69,4%), nível de pós-graduação (48%), raça/cor branca (64,2%), separados/solteiros (48,3%). A maioria dos participantes concordou com as medidas de flexibilização (41,1%), todavia consideraram os ambientes nada ou pouco adequados para a retomada das atividades cotidianas (com exceção dos locais abertos para atividades físicas). As medidas implementadas pelo Estado durante a pandemia por COVID-19 também foram tidas como pouco e nada adequadas. Houve mais chance de concordância com as medidas de flexibilização entre as pessoas que moravam/conviviam com trabalhadores expostos ao risco de contrair a COVID-19. Conclusão:de modo geral, houve concordância às medidas de flexibilização no país. Morar/conviver com trabalhador exposto ao risco de contrair a COVID-19 foi o principal fator associado à maior chance de concordar com as medidas de flexibilização, o que sinaliza a carga biopsicossocial trazida pela doença.
Estratégias de coping no processo gestacional e pré-natal em meio à pandemia covid-19
Authors: Silveira Cindy Macedo da , Bellaguarda Maria Lígia dos Reis , Nitschke Rosane Gonçalves , Ofugi Silvana Alves Benedet , Villarinho Mariana Vieira , Vieira Amanda Nicácio
Published: July 2023

Objetivo: identificar as estratégias de coping na história de mulheres no período gestacional no processo pandêmico da COVID-19. Método: Pesquisa qualitativa sócia histórica à luz da Teoria Motivacional. Participaram cinco mulheres que realizaram o pré-natal em Unidade Básica de Saúde de um município catarinense, entre março e dezembro de 2020. A análise dos dados seguiu a proposta história oral temática pela análise de conteúdo de Minayo e o software Iramuteq para análises multidimensionais de textos e questionários. Resultados: emergiram da relação entre a análise textual por semelhança das histórias referenciadas pelos participantes e, as características definidas pela teoria motivacional do Coping, necessidade de competência e apoio. Emergindo a categoria analítica O coping no gestar: mulheres e o pré-natal na pandemia COVID-19. Considerações finais: considera-se que o estresse na condição gestacional e período pré-natal na pandemia COVID-19 retratam estratégias de coping enquanto enfrentamentos positivos das mulheres.
Estratégias de enfrentamento utilizadas por crianças com câncer em tratamento quimioterápico
Authors: Menezes Larissa Fernandes de , Amador Daniela Doulavince , Marchetti Maria Angélica , Soldera Andrezza Gabrielly dos Santos , Mandetta Myriam Aparecida , Marques Fernanda Ribeiro Baptista
Published: July 2023

Objetivo: identificar as estratégias de enfrentamento utilizadas por crianças com câncer diante de uma situação difícil antes e após intervenção com jogo de tabuleiro. Método: Trata-se de um estudo de intervenção, realizado no ambulatório de quimioterapia de um centro de tratamento especializado em oncologia pediátrica de Mato Grosso do Sul. A amostra foi composta por 10 crianças de 7 a 12 anos em tratamento quimioterápico. Para a coleta de dados foi aplicada a escala Kidcope – versão infantil brasileira, antes e após a intervenção com o jogo de tabuleiro “Skuba! Uma aventura no fundo do mar”. Para a análise dos dados, utilizou-se estatística descritiva e inferencial. Resultados: as situações difíceis referidas pelas crianças foram de natureza pessoal e envolviam procedimentos invasivos durante o tratamento. Evidenciou-se o uso de estratégias de enfrentamento de evitação, como distração e pensamento mágico. As crianças revelaram, quanto ao uso das estratégias, que tentavam esquecer a situação difícil, através de atividades de distração, como assistir à televisão ou jogar um jogo, e não ficar sozinhas, evitando assim o isolamento social. Conclusão: as estratégias de enfrentamento utilizadas pelas crianças com câncer, mediadas pela intervenção com o jogo de tabuleiro, foram de evitação, com o predomínio da distração.
Adaptation of the Tumor Antigen Presentation Machinery to Ionizing Radiation
Authors: Lee Mi-Heon , Ratanachan Duang , Wang Zitian , Hack Jacob , Adbulrahman Lobna , Shamlin Nicholas P , Kalayjian Mirna , Nesseler Jean Philippe , Ganapathy Ekambaram , Nguyen Christine , Ratikan Josephine A , Cacalano Nicolas A , Austin David , Damoiseaux Robert , DiPardo Benjamin J , Graham Danielle S , Kalbasi Anusha , Sayre James W , McBride William H , Schaue Dörthe
Published: July 2023

Ionizing radiation (IR) can reprogram proteasome structure and function in cells and tissues. In this article, we show that IR can promote immunoproteasome synthesis with important implications for Ag processing and presentation and tumor immunity. Irradiation of a murine fibrosarcoma (FSA) induced dose-dependent de novo biosynthesis of the immunoproteasome subunits LMP7, LMP2, and Mecl-1, in concert with other changes in the Ag-presentation machinery (APM) essential for CD8+ T cell–mediated immunity, including enhanced expression of MHC class I (MHC-I), β2-microglobulin, transporters associated with Ag processing molecules, and their key transcriptional activator NOD-like receptor family CARD domain containing 5. In contrast, in another less immunogenic, murine fibrosarcoma (NFSA), LMP7 transcripts and expression of components of the immunoproteasome and the APM were muted after IR, which affected MHC-I expression and CD8+ T lymphocyte infiltration into NFSA tumors in vivo. Introduction of LMP7 into NFSA largely corrected these deficiencies, enhancing MHC-I expression and in vivo tumor immunogenicity. The immune adaptation in response to IR mirrored many aspects of the response to IFN-γ in coordinating the transcriptional MHC-I program, albeit with notable differences. Further investigations showed divergent upstream pathways in that, unlike IFN-γ, IR failed to activate STAT-1 in either FSA or NFSA cells while heavily relying on NF-κB activation. The IR-induced shift toward immunoproteasome production within a tumor indicates that proteasomal reprogramming is part of an integrated and dynamic tumor–host response that is specific to the stressor and the tumor and therefore is of clinical relevance for radiation oncology.
Impacts of sample ratio and size on the performance of random forest model to predict the potential distribution of snail habitats
Authors: Liu Yuanhua , Zhang Jun , P. Ward Michael , Tu Wei , Yu Lili , Shi Jin , Hu Yi , Gao Fenghua , Cao Zhiguo , Zhang Zhijie
Published: July 2023

Few studies have considered the impacts of sample size and sample ratio of presence and absence points on the results of random forest (RF) testing. We applied this technique for the prediction of the spatial distribution of snail habitats based on a total of 15,000 sample points (5,000 presence samples and 10,000 control points). RF models were built using seven different sample ratios (1:1, 1:2, 1:3, 1:4, 2:1, 3:1, and 4:1) and the optimal ratio was identified via the Area Under the Curve (AUC) statistic. The impact of sample size was compared by RF models under the optimal ratio and the optimal sample size. When the sample size was small, the sampling ratios of 1:1, 1:2 and 1:3 were significantly better than the sample ratios of 4:1 and 3:1 at all four levels of sample sizes (p<0.01) and there was no significant difference among the ratios of 1:1, 1:2 and 1:3 (p>0.05). The sample ratio of 1:2 appeared to be optimal for a relatively large sample size with the lowest quartile deviation. In addition, increasing the sample size produced a higher AUC and a smaller slope and the most suitable sample size found in this study was 2400 (AUC=0.96). This study provides a feasible idea to select an appropriate sample size and sample ratio for ecological niche modelling (ENM) and also provides a scientific basis for the selection of samples to accurately identify and predict snail habitat distributions.
Infermieri di Area Critica e Covid-19
Authors: Giusti Gian Domenico
Published: July 2023

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Relation between Biochemical Parameters and Bone Density in Postmenopausal Women with Osteoporosis
Authors: Salamat Mohammad Reza , Momeni Shokouh , Rastegari Ali Asghar
Published: July 2023

Background:

Osteoporosis is the most prevalent metabolic bone disease in postmenopausal women associated with reduced bone mass and increased bone fracture. Measuring bone density in the lumbar spine and hip is a reliable measure of bone mass and can therefore specify the risk of fracture. Dual-energy X-ray absorptiometry (DXA) is an accurate non-invasive system measuring bone density, with a low margin of error and no complications. The present study aimed to investigate the relationship between biochemical parameters with bone density in postmenopausal women.

Materials and Methods:

This cross-sectional study was conducted on 87 postmenopausal women referred to osteoporosis centers in Isfahan. Bone density was measured in the spine and hip area using the DXA system. Serum levels of calcium, phosphorus, alkaline phosphatase, and magnesium were measured by an autoanalyzer, and serum levels of vitamin D were measured by high-performance liquid chromatography (HPLC).

Results:

The mean parameters of calcium, phosphorus, alkaline phosphatase, vitamin D, and magnesium did not show a significant difference between the two groups (P-value > 0.05). In the control group, the relationship between alkaline phosphatase and bone mineral content (BMC) and bony area (BA) in the spine was significant with a correlation coefficient of − 0.402 and 0.258, respectively (P-value < 0.05) and BMD and T-score in the femoral neck area showed a direct and significant relationship with phosphorus (correlation = 0.368; P value = 0.038). There was a significant relationship between the Z-score with calcium (correlation = 0.358; P value = 0.044).

Conclusion:

There was no significant relationship between the values of calcium, phosphorus, alkaline phosphatase, vitamin D, and magnesium parameters and bone density (spine and hip) in postmenopausal women with osteopenia or osteoporosis.
24-Hydroxycholesterol Moderates the Effects of Amyloid-β on Expression of HMG-CoA Reductase and ABCA1 Proteins in Mouse Astrocytes
Authors: Nazeri Zahra , Mohammadzadeh Ghorban , Rashidi Mojtaba , Azizdoost Shirin , Cheraghzadeh Maryam , Kheirollah Alireza
Published: July 2023

Background:

Elevated brain cholesterol increases the risk of Alzheimer's disease. Production of 24-hydroxycholesterol (24s-OHC) by neurons prevents cholesterol accumulation in the brain. In this study, we investigated the effect of 24s-OHC on the HMG-COA reductase and ABCA1 which are involved in the brain cholesterol homeostasis with or without β-amyloid in astrocytes.

Methods and Materials:

Astrocytes were treated with 24s-OHC with or without Aβ. Western blot and real-time polymerase chain reaction were done to detect protein and gene expression of β-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) and ABCA1, respectively. Cholesterol release was determined using a quantitation kit.

Results:

Protein levels of HMGCR and ABCA1 were significantly increased by Aβ; however, the 24s-OHC was able to restore their levels and diminish the effect of amyloid-β. Aβ did not have a significant effect on HMGCR expression, while 24s-OHC reduced it by 68%. Aβ-induced ABCA1 expression did not increase cholesterol efflux as the lower levels of cholesterol in conditioned medium of Aβ-treated cells were found.

Conclusion:

Our novel findings show that Aβ affects two key elements in the brain cholesterol homeostasis, HMGCR and ABCA1, which are crucial in cholesterol synthesis and efflux. Since 24s-OHC could suppress the Aβ effects on enhancement of HMGCR and ABCA1, therefore the cytochrome P450 46A1 (Cyp46A1), which is exclusively expressed in the central nervous system and responsible for producing of 24s-OHC, could consider as a therapeutic target in the cholesterol-related neurodegenerative diseases such as Alzheimer's disease.
The Burden of Diabetic Foot Ulcers in Urban India: A Community Healthcare Setup-Based Study
Authors: Patil Priti , Mishra Satish , Gadgil Anita , Bhandarkar Prashant , Roy Nobhojit , Dwivedi Laxmi K.
Published: July 2023

Introduction:

Foot ulcer is the most common cause of hospitalisation among people with diabetes (PWD). The objective of the study is to determine the incidence of diabetic foot ulcers (DFUs) in the urban community in India and its relationship with glycemic level and demographic parameters like age and sex among diabetic patients.

Methods:

A retrospective observational study was performed from January 2016 to December 2018 at an urban community set up in Mumbai. The study was conducted in a healthcare setting, providing lifelong contributory healthcare to beneficiaries of an employees’ universal healthcare scheme. PWD from the community was identified using prescriptions of anti-diabetic medications. We identified patients with DFUs from electronic medical records from the hospital information system (HIS). The yearly incidence rate of DFU among PWD was estimated for the study period. The association between glycemic control and the demographic profile of patients with DFU was studied using binary logistic regression.

Results:

The study documents the average incidence of 66 DFU patients among 10,000 PWD per year in the community. Logistic regression analysis showed higher odds for the elderly age group (OR 2.863) compared to lower age for developing DFU. Similarly, poor control (HbA1c >7%) over glycemic level has a higher chance (OR 1.713) of DFU than that of optimum glycemic control (HbA1c ≤7%). Among the DFU, 15.29% of patients required amputation during the study period.

Conclusion:

The study documents the community-level incidence of DFUs among patients with diabetes. High glycemic levels and elderly age groups (≥60) are the associated risk factors for DFU.
Antenatal depression and anxiety in Indian women: A systematic review
Authors: Sahoo Swapnajeet , Gill Gursahiba , Sikka Pooja , Nehra Ritu
Published: July 2023

There is good evidence to suggest that high prevalence of depression and anxiety in the postpartum period. However, very few studies have focused on antenatal depression and anxiety disorders and their associated risk factors. Further, there are only a handful of studies from India on common antenatal mental health disorders. With this background, we reviewed the existing evidence on antenatal depression and anxiety from the studies conducted in Indian pregnant women during the antenatal period and to explore the associated risk factors. All the major databases were searched systematically for English language studies on prevalence and risk factors for antenatal depression and anxiety in Indian pregnant females, published during the period January 2000 to May 2022. Quality assessment of studies was done with the modified version of Newcastle Ottawa Scale for cross-sectional studies. We found the overall prevalence of antenatal depression was ranged from 3.8% to 65% and antenatal anxiety from 13 to 55%. The most relevant risk factors associated with antenatal depression and anxiety during pregnancy were preference to have a male child, intimate partner violence, history of abortions, marital conflict, poor relationship with the husband/in-laws and lack of social support. To conclude, the systematic review suggests that depressive and anxiety disorders are quite common in Indian pregnant women in antepartum period with varying prevalence depending on various settings and scales used. Steps should be taken to promote obstetricians for regular mental health screening during the antenatal visits and prompt referral to mental health professionals when suspected.
Depression, body image and quality of life in acne scars
Authors: Mahajan Sachin , Sawant Neena S. , Mahajan Sunanda
Published: July 2023

Background:

Acne scars commonly occur in almost 95% of adolescents having acne. Depression and the psychosocial impact of acne have been studied by previous researchers but there are few studies on acne scar patients.

Objectives:

To study the prevalence of depression, body image, and quality of life in patients with acne scars and the correlation of depression with body image and quality of life.

Material and Methods:

Around 81 patients above 18 years of age clinically diagnosed as having different grades of acne by a dermatologist were assessed for depression using Becks Depression Inventory, Body image concern inventory, and Dermatology Life Quality Index and included in the study after being informed consent.

Results:

The mean duration of acne was 6.03 ± 2.9 years, and acne scar was 2.88 ± 1.2 years. Nearly 93% of our sample had an equal preponderance of Grade 1 and Grade 2 acne scars. 31 (38.27%) patients had clinical depression with a total mean BDI score of 16.8 ± 9.7. 15 (18.5%) and 7 (8.6%) patients had moderate and severe depression respectively. Only 5 (6.17%) patients reported significant body image disturbances. All patients reported a very large effect on the quality of life due to flaws in facial appearance leading to feelings of embarrassment and impairment in sexual activities. Depression was significantly associated with grade 1 and 2 scars, body image disturbances, and quality of life.

Conclusions:

There is a high prevalence of depression in patients with acne scarring which needs to be detected and treated. Liaison with a psychiatrist would improve the outcome.
Reasons for recovery and readiness to change among adolescents and young adults engaging in self-injury
Authors: Meheli Saha , Bhola Poornima , Murugappan Nithya P.
Published: July 2023

Background:

Non-suicidal self-injury (NSSI) typically begins during adolescence and the process of treatment and recovery can be challenging. We examine NSSI through the lens of the Transtheoretical Model of Change, a framework that views the process of change as five stages, with differing degrees of readiness to change.

Methods:

Thirty participants, both adolescents and young adults (14 to 35 years), were recruited from a tertiary care neuropsychiatric hospital. The participants were predominantly female and had self-injured at least once in the last year. They completed the Inventory of Statements about Self Injury, the University of Rhode Island Change Assessment and the Reasons to Stop Self-Injury Questionnaire.

Results:

Seventy-three percent were in the contemplation stage with respect to their readiness to change, while the rest were in the pre-contemplation stage. Participants endorsed a range of vulnerability and resilience related reasons to stop injuring; reasons related to self-efficacy, the addictive nature of NSSI, self-efficacy and impact on interpersonal relationships were prominent levers for the recovery process. Preliminary trends indicated that participants in the contemplation stage endorsed reasons to stop self-injuring more strongly than those in pre-contemplation.

Conclusion:

The findings carry implications for assessment, the amplification of reasons for recovery and individualized interventions to support the recovery process with individuals who engage in NSSI.
Stress and coping among police personnel in South India
Authors: Savarimalai Rajamanikandan , Christy Jayakumar , Binu V. S. , Sekar Kasi
Published: July 2023

Background:

Police personnel experience the highest levels of stress due to the nature and demands of work. Though many researchers have studied these variables quantitatively, there is a lack of qualitative study, particularly in India.

Methods:

A qualitative study has been carried out to explore the stress and coping strategies of police personnel. This study conducted in-depth interviews with ten police personnel and three focus group discussions with 22 police personnel.

Results:

Thematic analysis revealed five themes: family stressor, personal stressor, work stressor, and adaptive and maladaptive coping. Inability to take leave, multi-tasking, unscheduled excessive working hours, inability to spend time with the family members, and lack of basic amenities to meet personal hygiene were significant factors for their high level of stress.

Conclusion:

The results reinforce the need for mitigating the impact of stress by using positive coping strategies and social support resources, which could be achieved through capacity building and mental health programs.
Hypomagnesemia and its association with calcineurin inhibitor use in renal transplant recipients
Authors: Elsayed Mohamed M. , Elgohary Iman E. , Abouelnaga Shady F. , Elian Fathyia A.S. , Zeid Montasser M.
Published: July 2023

Background

Hypomagnesemia is a common electrolyte abnormality following kidney transplantation. Increased renal magnesium (Mg) waste has been linked to calcineurin inhibitors. We aimed to assess the prevalence and risk factors of hypomagnesemia and its association with calcineurin inhibitor use in renal transplant recipients.

Patients and methods

This is a cross-sectional study carried out on renal transplant recipients, who underwent living-related donor kidney transplantation. All participants underwent detailed history taking and complete physical examination. Serum Mg, trough level of cyclosporine or tacrolimus, fractional excretion of Mg (FEMg), and 24 h urinary Mg, Ca, Ph, Cl, and protein were measured.

Results

One hundred patients were screened and 80 patients, with a mean age of 39.65 ± 12.14 years, completed the study. Fifty (62.5%) patients were on tacrolimus, and 26 (32.5%) patients were on cyclosporine. Patients had a median serum Mg of 1.80 mg/dl. Hypomagnesemia (Mg<1.7) was present in 17 (21.3%) patients with a median FEMg of 3.08%. There was significant negative correlation between serum Mg level and trough level of tacrolimus and FEMg with a P value of 0.038 and 0.001, respectively. The results of multivariate analyses showed that tacrolimus trough level (P=0.010) and FEMg (P=0.025) were independently correlated with serum Mg. Hypomagnesemia was significantly higher in tacrolimus-treated patients (30%) compared with only 7.7% in cyclosporine-treated patients (P=0.027).

Conclusions

Hypomagnesemia is common in renal transplant recipients, especially with tacrolimus use mostly due to increased renal Mg wasting. Increased tacrolimus trough level and increased FEMg were predictors of hypomagnesemia.
Spectrum of glomerulonephritis in adult Egyptians
Authors: Khaled Elzorkany M.A. , Ahmed El Arbagy R. , Mahmoud Kora A.A. , Ahmed Tawfeek R. , Noha Dewidar G.
Published: July 2023

Background

Glomerulonephritis (GN) is still the main cause of renal morbidity and mortality in the developing world. Knowledge about the characteristics of GN and its regional trends is mandatory for proper management of chronic kidney disease to decrease the incidence of progression to end-stage kidney disease. The aim of this study is to identify the patterns and frequency of glomerular lesions (biopsy-proven).

Patients and methods

This is a retrospective study that included 140 adult patients who underwent renal biopsies at Menoufia University Hospitals between August 2017 and December 2019. Patient demographics, clinical, laboratory, and histopathological data were recorded. The obtained data were analyzed using descriptive and inferential statistics.

Results

The studied patients were 72 (51.4%) males and 68 (48.6%) females, and their mean age was 36.11 ± 14.57 years. Focal segmental glomerulosclerosis (FSGS) was the most frequent cause of primary GN (21.4%) followed by membranous GN (13.6%), minimal change disease (5.7%), and membranoproliferative GN (3.6%). Lupus nephritis (LN) was reported as the most common in secondary GN (18.6%), followed by vasculitis (12.1%), amyloidosis (5.7%), thrombotic microangiopathy (4.3%), and infection-related GN (3.6%). The most common presentation was peripheral edema (80.7%), followed by acute kidney injury (14.3%). FSGS (12.1%) was the most common subtype of primary GN associated with renal insufficiency followed by membranous GN (10%). Vasculitis was the most common subtype of secondary GN associated with renal insufficiency (12.1%) followed by LN (7.1%).

Conclusion

FSGS and LN are the most common primary and secondary GN, respectively. Nephrotic syndrome and acute kidney injury were the major indications for biopsy. LN carried the best prognosis, while vasculitis carried the worst prognosis.
A Multicenter Experience of Inducible Clindamycin Resistance in Staphylococcus aureus Infection among 800 Egyptian Patients with or without Diabetes Mellitus
Authors: Helmy Housam Ahmad , AbdElhamed Mohamed Rashed , Youssef Mohamed I. , El Zamek Houssam M. F. , Kamal Ahmed , Abdelfattah Ahmed , Shabana Hossam , Abuamer Ahmed , Aboufarrag Galal Abdelhameed , Elshormilisy Amr Aly , Elwazzan Doaa , Saied Sara A. , Elfert Ashraf Yousif , Kamel Shimaa Y. , El Sharnoby Amal , Zedan Hendawy Abdel-moety , Gabr Basant Mostafa , Khalil Farag , Elmancy Ismail Mohamed , Lashin Hesham El-Sayed , AboShabaan Hind S. , Nassar Yousef , Elfiky Safa Reyad Abd Elsalam , Elkhadry Sally Waheed , Sakr Mohamed A. , Eid Ashraf M. , Kotb Sobhy Elsayed , Omar Marwa M. , El-Khayat Mohsen M.
Published: July 2023

Staphylococcus aureus causes a wide range of illnesses, from skin infections and persistent bone infections to life-threatening septicemia and endocarditis. Methicillin-resistant S. aureus (MRSA) is one of the most common bacteria that cause nosocomial and community-acquired infections. Clindamycin is one of the most effective treatments for several bacterial infections. Despite this, these infections may develop inducible clindamycin resistance during treatment, leading to treatment failure. This study determined the incidence of inducible clindamycin resistance among S. aureus clinical isolates. A total of 800 S. aureus strains were identified from clinical samples collected from several university hospitals in Egypt. All isolates were examined for the presence of MRSA using cefoxitin (30 μg) and the Kirby Bauer disk diffusion technique. The induction phenotypes of all 800 S. aureus strains were evaluated using the disk approximation test (D test), as recommended by the Clinical and Laboratory Standard Institute. Of the 800 strains of S. aureus, 540 (67.5%) were identified as MRSA and 260 (32.5%) were classified as methicillin-sensitive S. aureus (MSSA). In MRSA infections, clindamycin constitutive and inducible resistance was more frequent than in MSSA infections (27.8% versus 11.5% and 38.9% versus 15.4%, respectively). Clindamycin-sensitive strains were more prevalent in MSSA (53.8%) than in MRSA (20.4%) infections. In conclusion, the frequency of constitutive and inducible clindamycin resistance in MRSA isolates emphasizes the need to use the D test in routine antimicrobial susceptibility testing to evaluate clindamycin susceptibility, as the inducible resistance phenotype can inhibit the action of clindamycin and thus affect treatment efficacy.
Effects of Pre-spark Heat Release of Ethanol-Blended Gasoline Surrogate Fuels on Engine Combustion Behavior
Authors: Yoshimura Kei , Isobe Kohei , Kawashima Mitsutaka , Yamaguchi Kyohei , Sok Ratnak , Tokuhara Satoshi , Kusaka Jin
Published: July 2023

Regulations limiting greenhouse gas (GHG) emissions in the transport sector have become more restrictive in recent years, drawing interest to synthetic fuels such as e-fuels and biofuels that could “decarbonize” existing vehicles. This study focuses on the potential to increase the thermal efficiency of spark-ignition (SI) engines using ethanol as a renewable fuel, which requires a deep understanding of the effects of ethanol on combustion behavior with high compression ratios (CRs). An important phenomenon in this condition is pre-spark heat release (PSHR), which occurs in engines with high CRs in boosted conditions and changes the fuel reactivity, leading to changes in the burning velocity. Fuel blends containing ethanol display high octane sensitivity (OS) and limited low-temperature heat release (LTHR). Consequently, their burning velocities with PSHR may differ from that of gasoline. This study therefore aimed to clarify the effects of ethanol on SI combustion behavior under PSHR conditions. Combustion behavior was studied by performing single-cylinder engine experiments and chemical kinetics simulations. The experimental measurements were performed to characterize the relationship between the occurrence of PSHR and the main combustion duration. Analysis of this relationship showed that the ethanol-blended fuel has a lesser PSHR and a longer combustion duration than the non-ethanol fuel by approximately 5% in high engine load conditions. Simulations using input data from the experiments revealed that the ethanol-blended fuel has a lower laminar burning velocity due to the lower temperature in the unburned mixture caused by its PSHR. Additional simulations examining the chemical effect of partially oxidized reactants caused by PSHR on the laminar burning velocity showed that partially oxidized reactants increase the laminar burning velocity of the ethanol-blended fuel but decrease that of a reference fuel without ethanol. A large number of fuel radicals and oxides of the ethanol-blended fuel enhances chain-branching reactions in the pre-flame zone and possibly increases its laminar burning velocity. However, the thermodynamic effect of PSHR on laminar burning velocity exceeds the chemical effect, and thus the ethanol-blended fuel has a lower turbulent burning velocity in the PSHR conditions.
5395 SAYILI ÇOCUK KORUMA KANUNU’NA YENİ BİR KORUYUCU ÖNLEYİCİ TEDBİR ÖNERİSİ: REKREASYON VE SPOR TEDBİRİ
Authors: DURSUN Yunus , ATAMTÜRK Elvan
Published: July 2023

Korunmaya ihtiyacı olan çocuklara 5395 Sayılı Çocuk Koruma Kanunu kapsamında işlem yapılmaktadır. Bu kanunda, çocukların barınma ve bakım ihtiyaçlarının giderilmesine, eğitimlerinin devam ettirilmesine, sağlık ihtiyaçlarının karşılanmasına ve ebeveynlerine danışmanlık hizmetinin sağlanmasına yönelik koruyucu ve destekleyici tedbir kararları yer almaktadır. Bu kanununda çocukların eğitim, danışmanlık, sağlık ve bakım ihtiyaçlarının karşılanması için gerekli tedbir kararları bulunmasına rağmen onların biyo-psiko-sosyal gelişimleri açısından oldukça önemli olan ve onları pek çok risklerden koruyan özellikle serbest zamanlarının planlı bir şekilde değerlendirilmesine yönelik herhangi bir tedbir kararı bulunmamaktadır. Bu çalışmada spor, sanat ve kültürel faaliyetlerin çocuğun gelişimindeki olumlu etkisi vurgulanarak, hakkında değerlendirme yapılan ve korunma ihtiyacı içinde olan çocuklara ilişkin yeni bir tedbir kararının eklenilmesinin önerilmesi amaçlanmaktadır. İlk olarak çocuk korumaya ilişkin uluslararası ve ulusal mevzuata değinilmiş; sonrasında spor, sanat ve kültürel faaliyetlerin çocuğun gelişimindeki önemini ele alan çalışmalara yer verilmiş; sportif ve rekreasyonel faaliyetlerin bir koruyucu ve destekleyici tedbir olarak Çocuk Koruma Kanunu’nda yer almasının önemi vurgulanmaya çalışılmıştır.
GOD WHO SAW ME: Faith and Dehumanization of Exegesis Studies Genesis 16
Authors: Irawati Chandra Wahyuni
Published: July 2023

The story of Abram and Sarah is an interesting story to discuss. Chaotic household trips due to the issue of Sarah's infertility became a crucial problem that saddened both of them. In the ancient world, Sarah's barrenness was not only considered a disgrace in the family, but also a serious problem for Abram as a man who would have no heir. Impatience awaits offspring, and Sarah's suggestion for Abram to take Hagar turns out to be a domestic conflict and oppression of Hagar, the servant. But God's grace did not only apply to Abram and Sarah but also to Hagar.
Unveiling the Stories of the Rehabilitation Center Personnel in Dealing with Mentally Challenged Individuals: Phenomenological Study
Authors: D. Tabanas Jayhann , S. Galleros Christine , Denopol Jr Wilfredo A. , A. Labadesos Joshua , S. Vivares Kristal May , Cuevas Jr. Jose F.
Published: July 2023

This study explored the experience of personnel during their duties in It Works! Chemical Dependency Treatment Center, Tinago, Ozamiz City. The study used a qualitative approach using the phenomenological study Research design. Ten personnel from It Works! Tinago, Ozamiz City, who encountered many Challenges in dealing with mental challenges, were considered participants of the study. They were selected based on the following criteria: (1) personnel of the Rehabilitation center, (2) in serving six (6) months, (3) have direct contact with handling mentally challenged individuals, (4) willingness to participate. An interview was used to gather data. Analysis of the responses was done using Moustakas’ follow a flinty systematic procedure accessible to qualitative research transcendental phenomenological study. Results generated five themes: Passionate to help, Adversity in Dealing with Diverse Mentally Challenged Individuals, Maintaining Professionalism, and Ensuring the safety and well-being of the Patients; each employee at the rehabilitation center has a personal story about how they became interested in working with mentally challenged people. Hence, personnel must be physically, emotionally, and mentally ready when helping individuals find recovery.
DETEKSI LOKASI KENDARAAN MENGGUNAKAN GPS DAN GSM BERBASIS MIKROKONTROLER
Authors: Wahyudi Dona , Nalendra Adimas Ketut , Utomo Prabowo Budi
Published: July 2023

Objektif.  Deteksi lokasi kendaraan menggunakan GPS dan GSM berbasis mikrokontroler adalah topik yang menarik untuk diteliti karena dapat membantu dalam mengatasi masalah pencurian kendaraan. Beberapa penelitian sebelumnya telah dilakukan untuk mengembangkan sistem pelacakan kendaraan berbasis GPS dan GSM, seperti sistem pelacakan kendaraan hilang menggunakan GPS dan ditampilkan dengan smartphone, rancang bangun GPS sebagai pelacak dan pengaman kendaraan berbasis mikrokontroler ATMega128, serta sistem pelacakan dan pengamanan kendaraan berbasis GPS dengan menggunakan komunikasi GPRS. Penelitian ini bertujuan untuk mengembangkan sistem deteksi lokasi kendaraan menggunakan GPS dan GSM berbasis mikrokontroler. Sistem ini akan memanfaatkan teknologi GPS dan GSM untuk menentukan lokasi kendaraan dan mengirimkan informasi lokasi tersebut ke ponsel pengguna melalui jaringan internet.

Material and Metode.  Sistem yang akan dibuat dalam penelitian ini terdiri atas alat pendeteksi lokasi dan antarmuka pengguna berbasis web. Data lokasi didapat oleh GPS kemudian dikirimkan oleh mikrokontroller melalui jaringan GSM sehingga tersimpan kedalam database untuk ditampilkan melalui antarmuka berbasis web.

Hasil. Uji coba dilakukan untuk mendapatkan informasi kecepatan respon kedua alat beserta durasi alat bisa bekerja jika ditenagai dengan baterai 9V 450mAh. Komunikasi data antara perangkat dengan server menggunakan Wi-Fi. Diketahui bahwa kecepatan respon pertama antara ESP 32 dengan ESP 8266 memiliki perbedaan rata-rata sekitar 0.

Kesimpulan. Informasi lokasi bisa didapatkan dengan memanfaatkan mikrokontroller ESP32 maupun ESP 8266 dilengkapi dengan modul GPS. Data lokasi tersebut berhasil dikirimkan ke server menggunakan jaringan Wifi atau jaringan ISP. Informasi lokasi dan perangkat pengirim selanjutnya disimpan didatabase server melalui API yang dibuat khusus untuk masing-masing perangkat IoT ketika dilakukan penambahan data.
Emotional Intelligence of Irbid Governorate basic School Principals and its Relationship with their Leadership Performance
Authors: Alnadi Ameera Mohammad Ahmad , Shatnawi Nawaf Mousa
Published: July 2023

The objective of the study was to identify emotional intelligence level among basic school principals at Irbid governorate and its relationship with their leadership performance from teachers’ point of view. The population of the study included all basic school teachers at Irbid governorate. The instrument of the study was developed and included two sections: The first was (37) items to measure emotional intelligence level, while the second was (24) items to measure leadership performance. The instrument was administrated to a sample totaling (412) male and female teachers selected from basic schools at Irbid governorate. Validity and reliability of the instruments were obtained. The results of the study showed that emotional intelligence was moderate; and that leadership performance was also moderate. It was found that there was a positively significant statistical correlation between basic schools principals’ emotional intelligence level at Irbid governorate and their leadership performance from teachers’ point of view. In light of these results, the study recommended the necessity to spread the culture of issues related to emotional intelligence among school administrations, and to clarify its role in the success of individuals in leadership and professionally.
The Predictability of Self-Esteem on the Motivation towards Learning among Students in the Upper Basic Elementary Grades in the Latin Patriarchate Schools in Jordan
Authors: Nasrawin Firas Jiries
Published: July 2023

This study aimed to describe the predictability of self-esteem on the Motivation towards learning among students in the upper elementary grades in the Latin Patriarchate schools in Jordan. The sample of the study consisted of (338) students from the Latin Patriarchate schools in Jordan for the academic year 2019/2020.To achieve the purposes of the study, the researcher developed two measures were used for the purposes of this study, Motivation scale, prepared by (Corpus, Iyengar,, Lipper, 2005) from its original version originally prepared by Harter (Harter, 1980,1981), self-esteem scale (Echelle Toulousaine d'Estime de Soi) prepared by (Oubrayrie, N., de Léonardis, M. et Safont-Mottay, C. 1994). The results of the study showed that the level of motivation was high and the level of self-esteem was medium among the sample of the study, and the results also showed a positive correlation between self-esteem and the motivation among the sample of the study. The main recommendation of this study is to conduct more studies about the relationship between Self-esteem and motivation towards learning.
The Reality of Including Pre-University Education Policies at the Sultanate of Oman for the Purposes of the Fourth Goal of the Sustainable Development Goals 2030
Authors: Al-Haadi Badriya Bint Rashid , Al-Kiyumi Amel Bint Rashid , Al-Abri Khalaf Bin Marhun
Published: July 2023

The study aimed to identify the reality of including pre-‎university education policies in the Sultanate of Oman ‎for the purposes of the fourth goal of the sustainable ‎development goals (2030) according to the dimensions ‎set by the study (compulsory of education, educational justice and quality of education).The study applied   the descriptive methodlogy and used the qualitative ‎method through the content analysis form to analyze a ‎number of educational documents in the Sultanate of ‎Oman. The results showed that the ‘Quality of ‎Education’ dimension obtained the first rank as the ‎most included dimension in the documents subject of ‎analysis with a general mean of (13.6), whereas the ‎dimension ‘compulsory of education’ came second, ‎while the ‘educational justice’ dimension ranked last. ‎The study recommended the importance of paying ‎more attention from educational policy ‎makers to pre-‎school education، and caring about ‎special education to ‎achieve justice in education.
Determinants of First College Major Choice among Yarmouk University Students and Estimating their Scaling Values Using Three Scaling Methods
Authors: Brahmeh Razan Rasmi , Sawalmeh Yousef Mohammad
Published: July 2023

The study aimed at determining the determinants of first college major choice for Yarmouk University students, and estimating their scaling values using three different scaling methods, and determining the extent of agreement among these methods.  To achieve the purpose of the study, (165) male and female students from the university colleges volunteered to determine the determinants primarily, and two equivalent samples with regard to gender and college type were used to collect the scaling data. The first consisted of (120) male and female students studying a major which is their first choice, the second consisted of (120) male and female students studying a major differs from their first choice. The scaling values on importance scale were estimated using the Law of Comparative Judgments, Direct Estimation and the Law of Catogerical Judgments. The results showed that the most important major choice determinants are: opportunities to obtain work, secondary school exam scores mean, personal desire, and admission opportunities. Also, it was found that there was a consistency among scaling methods in ranking the determinants on the importance scale.
Probable Kennedy Disease Mimicking Hirayama Disease: A Case Report
Authors: Jang Soo-Im , Park Soo-Hyun , Choi Seul-Gi , Lee Sae-Nal , An Ji-Yoon , Kim Nam-Hee
Published: July 2023

Spinal and bulbar muscular atrophy (Kennedy disease) is an X-linked, adult-onset motor neuron disease characterized by slow, progressive weakness of the bulbar and extremity muscles with CAG triplet repeat expansion in the androgen receptor gene. Hirayama disease (HD) is characterized by the juvenile onset of asymmetric weakness and amyotrophy of the hand and is most common in males in Asia. We report a patient with atypical Kennedy disease presenting with asymmetric hand weakness and atrophy typical of HD.
PENGARUH PROFITABILITAS, TINGKAT PERTUMBUHAN DAN TINGKAT PAJAK TERHADAP STRUKTUR MODAL PADA PERUSAHAAN REAL ESTATE DAN PROPERTY YANG TERDAFTAR DI BURSA EFEK INDONESIA PERIODE 2017-2019
Authors: Khadijah Siti , Rozi Facrul , Nursidin Muhammad
Published: July 2023

This study aims to analyze the specific effect of Asset Growth Rate, Tax Rate on Capital Structure inReal Estate and Property companies listed on the Indonesia Stock Exchange (IDX). The sample in thisstudy is 40 real estate and property companies that publish fully audited financial reports. The type ofdata used is secondary data obtained from the financial reports of each Real Estate and Propertycompany for 3 years, namely 2017-2019. Data analysis using multiple linear regression analysis. Theresults of this study indicate that the variable profitability (ROE) has a negative and significant effect onthe capital structure of Real Estate and Property. Meanwhile, the asset growth rate and tax rate have apositive and insignificant effect on the capital structure of Real Estate and Property companies
Soft and Hard Elements in the Town Square of Bangli
Authors: Ni Putu Eka Apriastuti  , Putu Surya Anggaraditya  , Dicky Marsadi
Published: July 2023

Soft and hard elements are mandatory components in the garden. Both of these elements play an important role to give the impression of beauty in the garden. This study aims to find out what are the soft and hard elements in Bangli City Square Park. The location of this research was carried out in Bangli City Square Park. The determination of the research location was carried out deliberately with the consideration that this location is strategic and is in the center of Bangli City so that it becomes an attraction for visitors. Data collection techniques using the method of observation, interviews and documentation. The data analysis used is descriptive analysis by describing the hard and soft elements and their maintenance techniques. The research results showed that there were 15 soft elements consisting of Litchi chinensis, Zoysia Japonic, Hibiscus, Terminalia mantaly, Plumeria, Cocos nucifera, Bougainvillea, Casuarinaceae, Streblus asper, Arenga pinnata, Cycas, Cactaceae, Garcinia mangostana, Saraca asoca, Cyrtostachys lace and there are 4 felt elements consisting of statues, trash cans, ponds, garden lights.