bluuebunny/crossref_metadata_2025 huggingface dataset:
Review of TAM used in Educational Technology Research: A Proposal
Authors: TANG Kai-Yu , HSIAO Chun-Hua
Published: February 2025

Since the research on user acceptance of information technology was introduced by Fred D. Davis in the 1980s, two critical constructs (perceived usefulness and ease of use) and the technology acceptance model (TAM) have generated significant impacts on information science and management information system literature. In the early 2000s, educational technology researchers began to adopt TAM-related concepts to explain teaching and learning contexts. For example, Selim (2003) conducted research on empirically examine students' acceptance of course websites and published on Computers & Education. Accordingly, this proposal paper extends the authors' previous works (Hsiao & Yang, 2011; Hsiao, Tang & Liu, 2015; Hsiao & Chen, 2019; Tang, Hsiao & Hwang, 2022) to trace the latest development of educational technology research using TAM-related framework. In this proposal, we have identified a total of 366 articles with 20,242 citations. For the data analysis, we proposed a series of analyses (e.g., bibliometrics, main path analysis, document co-citation analysis, and social network analysis) to examine the knowledge trajectory in this field. This study is the first attempt to propose a research framework with a series of analyses to systematically analyze and review the longitudinal development of research using a TAM-related framework in educational technology. With this attempt, some significant turning points (e.g., theoretical converging and diverging points) can be further explored in the network diagram to identify the critical constructs, models, and theories in educational technology research. Overall, established on a large number of citation data, the results of this study aim to provide a platform for academic discussion and to make a prediction for the future trend of educational technology research.
Effectiveness of Synchronous and Asynchronous Online Learning in Bloom's Taxonomy Framework
Authors: Wong Cheryl Sze Yin , HOANG Lily , TAN Chin Tuan
Published: February 2025

Synchronous and asynchronous Learning is usually highly-structured, with course activities, assessments, and technology requirements explicitly written and scheduled. It allows great flexibility and accessibility for learners with strict alignment to the learning outcomes and module learning objectives. However, it is not clear that such synchronous or asynchronous learning is effective in different levels of courses which may require different levels of cognitive meta-process, knowledge dimensions and combination of both. In this paper, we re-aligned meta-analysis data by Zeng et al. 2023 in cognitive process and knowledge dimensions under revised Bloom's Taxonomy framework. We proposed a metric to compute cognitive complexity level on the re-aligned data. Our proposed metric was able to show that synchronous classes are more suitable for basic cognitive domain learning of factual knowledge and conceptual knowledge, while asynchronous classes are more suited to higher cognitive domain learning of procedural knowledge and metacognitive knowledge. Likewise, our further grouping in educational level were also able to show that asynchronous classes are more effective for learning at higher education levels when the subjects of learning are usually in higher knowledge dimensions. Both observations are congruent in expected trend of cognitive complexity.
A Proposal and Evaluation of Learning Advising using a Generative AI
Authors: TAKANO Yasuomi , TSURUBE Taketo , UENO Haruki , KOMATSUGAWA Hiroshi
Published: February 2025

In this paper, we propose and evaluate a method in which learner’s learning history and information about goal setting and reflection are provided as prompts to Large Language Models (LLM) that enables automated learning advice generated. The proposed approach allows us to generate advice messages that are relevant to the learner’s learning properties, using learners’ own sentences for reflections and goal settings. The generated advice is evaluated from the point of view whether it is similar to the actual teacher’s one.
Question-Driven Design Process for XAI in Active Video Watching
Authors: LUMAPAS Raul Vincent , MITROVIC Antonija , GALSTER Matthias , MALINEN Sanna , PEIRIS Pasan , HOLLAND Jay
Published: February 2025

Designing explanations for Artificial Intelligence (AI) systems continues to be a challenge due to AI's black-box nature. Among the solutions developed to help in designing explanations in AI technologies is the Question-Driven Design Process for Explainable Artificial Intelligence (XAI) User Experience. In this paper, we report on our experiences using the question-driven design process for XAI in active video watching. We used Active Video Watching (AVW)-Space, an AVW platform developed at the University of Canterbury, as the context for AVW. In the question analysis process, we elicited questions from users on the AI features of the system. We conducted a survey to elicit questions from users on the AI features of the system. We conducted a survey to elicit three human raters categorized the user questions into the different XAI bank categories. Results show that most users tend to ask "how" and "why" questions about the AI-enabled features in the platform. The results of the question analysis will be used in mapping the determined question categories to potential XAI techniques. This can help in deciding the types of explanations to provide to users of AVW in future works on XAI in active video watching.
Practices of ARCS Chinese language instructional design with MR application participation
Authors: SHI Zhenni , NAGATA Yuto , MORITA Yusuke
Published: February 2025

This inquiry employed the ARCS instructional design theory and an author-developed Mixed Reality (MR) application. To ascertain its efficacy, seven Chinese language learners who are Japanese native speakers, consisting of three males and four females (average age = 44.43 years, SD = 16.59), participated in a validation experiment. They were divided into two groups and underwent three times 100-minute Chinese language classes. The MR application, rooted in TPR, gamification, and engagement theories, emphasizes individual learning and integrates shared experiences in mixed reality, fostering collaborative learning. Evaluation encompassed engagement, motivation, learning strategies, achievement scores, and affective scales. The outcome reveals enhanced intrinsic motivation and collaborative engagement after three times classes.
Development of a Music Educational Board Game with Mobile Device: Learning Musical Theory and Emotional perception through Gameplay
Authors: XIAO Song-Zhu , KUO Chih-Chen , HOU Huei-Tse
Published: February 2025

Music appreciation is one of the most important courses in arts education. In this study, we designed a music education board game "Soul Mate" with mobile devices, which provided learners with multiple representations learning context. In the game, learners scan the QR codes on the cards with their mobile devices to listen to the music. Through the process of listening experience, learning experience and observing interaction, learners can make judgment, understand their own emotional perception of listening to music, and learn about music theory. Preliminary results indicate that gamified learning is effective in enhancing learners' learning outcomes and is able to maintain learners' flow and keep them engaged in learning.
Design and Preliminary Evaluation of an Educational Board Game on Urban Culture and History with Mobile Conceptual Scaffolding
Authors: YU Hau-An , KUO Chih-Chen , HOU Huei-Tse
Published: February 2025

With the development of urbanization, local towns are at risk of losing their local culture as a result of out-migration. Local literature and history education is limited by time and teachers’ qualifications. In this study, we designed a board game “Walking on Puzi Street” to assist students’ learn local history and culture by combining scaffolding on the cards with the mobile conceptual scaffolding provided from the mobile app. Learners take on the role of a tour guide, leading travelers on a tour of the town of Puzi in Taiwan. The preliminary study investigated participants’ flow, acceptance and sense of place. The results showed that the game mechanism can engage learners in the game, facilitate local literature and history learning, and bring them sense of interest in the place. Also, high rates of learners used mobile scaffolding.
Estimation of Features and Skills of Drawing Experts by Tracing Figures
Authors: TAMURA Yasuhisa , KAIZU Kazunari , HAMANO Akito
Published: February 2025

This paper focuses on estimating expert-specific characteristics and skills of art drawing, with use of figure tracing log data of pen strokes. In order to verify hypothesis, the authors acquired stroke data of simple figure drawing with use of Tablet PCs and digital pens. Afterwards, we compared the log data of novice learners with one of experts. As a result, we could not find significance between novices and experts in 8 target parameters. However, we found some tendencies of experts. These tendencies imply some training methods in art education.
Analysis of the performance of algorithms (K-Means, Farthest First, Hierarchical) Using the data analysis and modeling tool Weka
Authors: Abdulkareem Mohammed Basil
Published: February 2025

This study assesses the performance of three clustering algorithms—K-Means, Farthest First, and Hierarchical—using the Weka data mining tool. These algorithms were applied to five diverse datasets representing healthcare, industrial, and benchmark applications to evaluate their clustering accuracy, execution time, and consistency. The experimental results show that the Farthest First algorithm achieves the highest accuracy and the fastest execution time, making it suitable for real-time applications. K-Means delivers balanced performance but is sensitive to initialization and outliers, while the Hierarchical algorithm effectively captures complex relationships but incurs high computational costs. The findings highlight the importance of selecting appropriate clustering techniques based on dataset characteristics and application requirements. Future work will explore advanced clustering methods such as DBSCAN and Gaussian Mixture Models to improve scalability and performance on large datasets.
Limbajul de programare Python 3 pentru non-programatori
Authors:   Romanian Academy, Sfetcu Nicolae
Published: February 2025

Python a devenit unul dintre cele mai populare și utilizate limbaje de programare din lume, celebru pentru lizibilitatea, suportul comunității și diversele domenii de aplicație. Simplitatea și curba de învățare abordabilă atrag începătorii, în timp ce capabilitățile și bibliotecile sale extinse atrag profesioniștii experimentați. Python 3 este cea mai recentă versiune majoră a acestui limbaj, oferind dezvoltatorilor funcții îmbunătățite, sintaxă mai curată și paradigme de programare moderne care continuă să modeleze peisajul tehnologic.
De la începătorii care își scriu primele programe până la giganții din industrie care alimentează aplicații bazate pe date, Python 3 atinge un echilibru impresionant de lizibilitate, versatilitate și performanță. Pe măsură ce versiuni și funcții mai noi continuă să fie lansate, Python 3 rămâne pregătit să răspundă nevoilor în evoluție ale dezvoltatorilor în domenii precum știința datelor, inteligența artificială, dezvoltarea web și nu numai.
Identification of Dermatophytes Causing Tinea Unguium in Fisherman in Tanah Lemo Subdistrict
Authors: Asdinar Asdinar , Ananda Alya , AB Aszrul
Published: February 2025

Nail infection or tinea unguium is a disease caused by dermatophyte fungi and often occurs in fisherman due to their activities in wet environments without protection such as gloves or boots. Common symptoms found include nail damage, thickening, nail lifting, uneven broken nails, loss of shine, and discoloration to yellow, brown, or black. This study aims to identify the types of dermatophyte fungi that cause tinea unguium in fisherman in Tanah Lemo Village. This study used a qualitative approach with a fungal culture method using Saboraud Dextrose Agar (SDA) media and microscopic examination using 10% KOH solution. The study population was 115 fisherman, with samples of 25 people taken from their nails through macroscopic and microscopic examination methods. The results showed that a wet and dirty work environment is a major risk factor for fungal infections in fisherman's nails. The implication of this study is the importance of prevention efforts through education on the use of personal protective equipment, such as gloves and boots, to reduce the risk of fungal infections. Additional factors such as the length of exposure to wet environments also affect fungal growth, so better risk management of the work environment is needed.
Development of Augmented Reality Based Learning Media for Computer Hardware Materials at SMP Santa Monika
Authors: Istiqomah Dara Nur , Astuti Reni , Santoso Danar
Published: February 2025

This study aims to develop augmented reality-based learning media for computer hardware materials for Grade VII students at SMP Santa Monika. The research method employed is Research and Development (R&D) using the ADDIE design model, which consists of Analysis, Design, Development, Implementation, and Evaluation. The product development subjects include expert validators in media and material: two lecturers in Information Technology Education, one lecturer in Information Technology Education, and an informatics subject teacher. The small-scale and large-scale product testing subjects consist of Grade VII students at SMP Santa Monika, with a total of 40 students. Data collection techniques used in the study include direct communication, indirect communication, and data collection tools such as unstructured interviews, questionnaires, and documentation. Based on the results obtained, the conclusion of this study is that the augmented reality-based learning media developed is feasible for use in the learning process. The validation results from media and material experts achieved an average percentage of 89.75%, categorized as highly feasible. Additionally, the student response questionnaire results in the small-scale trial showed a percentage of 80.33%, while the large-scale trial achieved 89.74%, both categorized as excellent.
The Relevance of the Kuttab Learning Model in Building a Generation of Noble Character
Authors: Azzahra Naila Zalva , Anwar Saepul , Romli Usup
Published: February 2025

This study aims to explore the effectiveness of the Kuttab-based learning model in shaping students' character and academic performance, as well as identify challenges and opportunities for its implementation in modern education. The method used is a literature review by collecting data from books, articles, and other relevant sources. The collected data were grouped into key themes, such as the history of Kuttab, principles of religion-based education, and the challenges and advantages of this model. Analysis was conducted to identify relevant patterns and synthesize information to support the research objectives. The results show that Kuttab education is vital in integrating religious knowledge and science, creating intellectual and spiritual balance. This model effectively shapes a generation that is intelligent and morally upright. Despite challenges like limited infrastructure and globalization, Kuttab holds significant potential for character education. The use of technology and the integration of religious curriculum with general sciences offer opportunities for developing a morally and intellectually excellent generation. Thus, Kuttab-based education can serve as a modern solution emphasizing the balance between moral values and knowledge. 
 
Keywords: Kuttab Education, integration of religion and science, character development, educational challenges, technology in education.
365 Way-markers : daily flash lights for ethics in everyday life
Authors: Stückelberger Christoph
Published: February 2025

How can I live out my values and convictions in everyday life? How can I reconcile faith and action? How can we encourage one another in what we do instead of giving up to resignation? Such questions are at the centre of these 365 short texts, written out of and for everyday life: way-markers offering a sense of direction and encouragement. These aphorisms and reflections are centred around seven themes: 1. Creation, the senses and environment; 2. Good and evil, virtue and vice; 3. Life, energy and being human; 4. Poverty, wealth and justice; 5. Relationships, love and sexuality; 6. Economics, technology, globalisation, media; 7. Politics, globalisation, law, nationalism; 8. Spirituality, faith, knowledge, 9. Churches and religions.
Factor Analysis of the Classroom Management Attitude Scale: Dimensions of Teacher Perspectives
Authors: Dr. Ayesha Saleem  , Dr. Farah Fida  , Yaar Muhammad
Published: February 2025

This study used exploratory factor analysis to determine how the Classroom Management Attitude Scale (CMAS) functions as a whole. The CMAS evaluates teachers’ attitudes and approaches toward various aspects of classroom management in Pakistan. The research team obtained responses from 500 teachers working in different school environments. Several statistical tests were conducted to study how well the scale measures what it intends to measure. The sampling adequacy score KMO .967 confirms an excellent sampling adequacy for factor analysis. The Test of Sphericity by Bartlett confirmed that the correlation matrix was suitable (p < .001) for factor analysis. Our analysis used principal axis factoring with oblimin rotation to find latent constructs. The analysis retained factors based on scree plot results and only selected factors with an eigenvalue above 1. Through analysis, our team identified five key areas, which explained 83.179% of all variations. Extracted factors were: Five key factors outline teacher classroom management attitudes: (1) Instructional Planning and Organization, (2) Behavioral Management Strategies, (3) Student-Teacher Relationships, (4) Classroom Climate and Environment, and (5) Technology and Resource Management. Factor loadings exceeding .40 were considered significant. The study reviewed communalities along with the factor correlation matrix to see how well items reflected their assigned factors and how these factors worked with each other. The current factor structure helps us understand classroom management attitudes’ multidimensional nature while helping design effective professional development for teachers. Next research studies need to validate this factor structure across different groups and study how it can be effectively used in school education settings.
Diamonds and Dependency: A Case study of Blood Diamond
Authors: Muhammad Waseem  , Rehan Ashfaq  , Zainab Waheed  , Maryam Nawaz
Published: February 2025

This study focuses on elements of dependency in the movie "Blood Diamond with the lens of Raul Prebisch's dependency theory in the movie "Blood Diamond”. The study implements qualitative data analysis, guided by the principles of dependency theory. The data for research is collected in the form of dialogues from the movie "Blood Diamond" and the dialogues are discussed in detail with contextual analysis to uncover the elements of dependency. The findings reveal that the film serves as a tool to understand the cycles of exploitation of resources-rich countries by wealthier nations which causes dependency of resource-rich countries on foreign countries. This research is limited to some dialogues related to dependency leaving the room for future researchers for further researches.
Status of technology utilization in science-based instruction in selected schools in Sarangani, Davao Occidental, Philippines
Authors: Arellano Arra C , Lumogdang Leonel P
Published: February 2025

This study reported the status of technology utilization in Science-Based Instruction in the schools of Sarangani District, Davao Occidental. It was conducted during the academic school year of 2022-2023. Forty-eight elementary and junior high school teacher respondents from fifteen (15) schools were interviewed using validated survey questionnaires. The results showed that laptops, desktop computers, printers, USB flash drives, and speakers were commonly used technological tools. Moreover, the science teachers were moderately skilled in utilizing technology in science-based instruction. Regarding the level of technological implementation, the science teachers have slightly applied technology integration in science instruction. At the same time, they practiced technology integration in the implementation of science instruction, and the training programs were provided. To improve technology utilization on Sarangani Island, the DepEd has to allocate more educational technology capability-building training for teachers. Moreover, DepEd has to establish active partnerships with local and provincial government units to improve its facilities and resources, namely electricity and internet connectivity.
Pasien laki-laki dengan STEMI Anteroseptal pada Rumah Sakit dengan Fasilitas Terbatas , Sebuah Laporan Kasus
Authors: Kahowi Asrina Rery
Published: February 2025

Sindroma koroner akut (SKA) adalah manifestasi klinis akibat aliran darah ke otot jantung yang terganggu, sering ditandai dengan nyeri dada iskemik dan perubahan elektrokardiografis. Penanganan optimal menjadi tantangan, terutama di rumah sakit dengan fasilitas terbatas. Laporan kasus ini bertujuan memberikan gambaran diagnosis dan tatalaksana STEMI anteroseptal pada rumah sakit dengan keterbatasan fasilitas.Penelitian ini menggunakan pendekatan laporan kasus retrospektif pada pasien laki-laki 68 tahun dengan STEMI anteroseptal. Data mencakup anamnesis, pemeriksaan fisik, penunjang, serta intervensi terapi seperti fibrinolisis, fondaparinux sodium, dan MONACO di ruang gawat darurat.Terapi fibrinolisis dilakukan segera karena fasilitas IKP primer tidak tersedia. Perbaikan klinis dan elektrokardiografis pasien terlihat sejak hari kedua perawatan di High Care Unit (HCU), dengan kondisi stabil pada hari keenam.Fibrinolisis menjadi pilihan terapi utama untuk pasien STEMI anteroseptal di fasilitas dengan keterbatasan sumber daya, menunjukkan hasil yang efektif dan dapat menjadi pedoman di situasi serupa.
Nuevo geoportal gestionado por el Instituto Geográfico Nacional y el Plan Nacional de Teledetección. Imágenes satelitales de muy alta resolución para las AAPP
Authors: Bermejo Priego José Luis
Published: February 2025

El Instituto Geográfico Nacional (IGN) ha desarrollado un nuevo portal de descarga de imágenes de teledetección espacial de alta resolución. El objeto de este portal es facilitar a las Administraciones Públicas la visualización y descarga de las diferentes coberturas del Plan Nacional de Teledetección (PNT). Actualmente se dispone de tres coberturas de la totalidad de nuestro territorio con imágenes espaciales de alta resolución (2021, 2022 y 2023). Esta revisita anual, superior a la periodicidad del Plan Nacional de Ortofotografía Aérea, potencia y complementa su aplicación en sectores como la agricultura, medio ambiente, ingeniería y un largo etcétera.
«Naturaleza, cultura y ocio», un visualizador colaborativo
Authors: Alemany Gómez Laura
Published: February 2025

El visualizador web «Naturaleza, Cultura y Ocio» (NCO) ha sido desarrollado por el Instituto Geográfico Nacional (IGN) y el O. A. Centro Nacional de Información Geográfica (CNIG) con el objetivo de facilitar la planificación de actividades de ocio y tiempo libre en España. Este recurso, disponible en español e inglés, centraliza información turística de diversos organismos colaboradores. El proyecto se apoya en convenios de colaboración firmados con otras organizaciones y asociaciones responsables de diferentes contenidos culturales, medioambientales, históricos, etcétera, que aportan, mantienen y actualizan la información. El IGN y el CNIG se encargan de homogeneizar y pasar un control de calidad a los datos recibidos para publicarlos en el visualizador. Entre sus funcionalidades se destacan la búsqueda de lugares de interés, la descarga gratuita de los datos (con licencia CC BY 4.0), el análisis de las rutas mediante perfiles longitudinales, la posibilidad de imprimir mapas personalizados y la integración en otros sitios web del propio visualizador. Las 150.000 visitas mensuales que recibe el visualizador muestran que NCO es útil y mejora la experiencia del usuario en la planificación de actividades de ocio y tiempo libre, contribuyendo a un turismo más informado y sostenible.
Downregulation of IL-6 and TNF-α Expression with Mesenchymal Stem Cells Therapy in Allergic Rhinitis Rats Models
Authors: Restimulia Lia , Dewi Dian Andriani Ratna , Nazar Mohammad Ariq , Irawan Risky Chandra Satria , Ghaissani Shabrina Syifa , Haryono Erlina
Published: February 2025

Rhinitis is an inflammatory that characterized by nasal symptoms due to the condition of the nasal mucosa that trigerred by an interaction between environmental allergens and immunoglobulin (Ig)E. It is driven by host factors, infection, pathogens and various inflammatory pathways such as TNF-α that released in allergic responses from both mast cells and macrophages through IgE-dependent mechanisms. Secretome hypoxia mesenchymal stem cells (SH-MSCs) contain anti-inflammatory soluble molecules were able to improve the conditions of endothelial damage, inflammation and oxidative stress by decreasing levels of IL-6, TNF-α, ROS and increasing eNOS. This study will investigate the effect of SH-MSCs at a dose of 300 µL on TNF- and IL-6 expression in rat model ovalbumin-induced rhinitis in vivo. Thirty male Wistar rats were randomly divided into 3 groups: control, treatment and sham group that administrated through intramuscular injection. The results of this study found that SH-MSCs can downregulate the inflammatory cytokines TNF-α and IL-6 in rat model ovalbumin-induced rhinitis in vivo
Hypoxia Precondition Enhance the Therapeutic Effects of Mesenchymal Stem Cells via regulating TGF-β1 and IL-10 serial expression in Skin Excision Rat Models
Authors: Kustyah Azizah Retno , Fatimah Nandiah , Rizkiyani Elytia Mutia , Ramadhanti Olifiarsy Wiet , Istiqomah Dyah Ayu Fitri , Hidayah Nurul , Bhirau Wilaksono
Published: February 2025

Background: The skin excisional wound healing process involves an intricate-regulated series of cellular responses to reverse the formation of skin tissue integrity. This process requires paracrine communication involving anti-inflammatory cytokines and growth factors, especially interleukin 10 (IL-10) and TGF-β. On the other hand, hypoxic preconditioned mesenchymal stem cells (Hypoxia-MSCs) have been acknowledged to enrich IL-10 and TGF- β secretion contributing to accelerated wound healing compared to normal preconditioned mesenchymal stem cells (Normoxia-MSCs). Objective: This study aimed to compare Hypoxia-MSCs and Normoxia-MSCs in integrating the serial expression of IL-10 and TGF-β associated with improved collagen density in animal models of excision wounds. Methods: Thirty-six male Wistar rats with excision wounds were made as animal models using the 6 mm biopsy method. The rats were randomly divided into four groups consisting of four treatment groups: N-MSCs 1x106, H-MSCs 1x106, Control (PBS treatment), and Sham (untreated or healthy mice). The treatments were administered 2 times intraperitoneally on day 0. Skin tissue was collected on days 12, 18, and 24 post-injections. IL-10 dan TGF-β expressions were examined by qPCR. Results: This study showed that there was a significant increase in IL-10 and TGF-β after Hypoxia-MSCs and Normoxia-MSCs treatment compared to the Control group. Conclusion: Hypoxia-MSCs can improve the serial expression of IL-10 which leads to wound repair of the mouse model of excision wound. These results suggest that a hypoxic environment can enhance the therapeutic effect of MSCs.
Psycho-Neuro-Autonomic Aspect of Burnout Syndrome: A Literature Review
Authors: Oliviera Ivona , Ardani Yanuar , Shatri Hamzah
Published: February 2025

Background: Burnout syndrome are symptoms resulting from stress due to burden and stressors of high workload, as seen in health workers. Burnout syndrome can trigger psychological and physiological disorders, mainly related to the autonomic nervous system and the Hypothalamus-Hypophysis Axis pathway. Psychological disorders could be assessed using Maslach Burnout Inventory (MBI), while physiological disorders of the neuro-autonomic imbalance could be assessed using Heart Rate Variability (HRV). Aim: To study about the psycho-neurological aspect of burnout syndrome. Methods: A systematic literature review using the PRISMA method, through four stages, namely identification, screening, feasibility, and accepted results. Results: Literature search was performed using PubMed and Google Scholar databases. Seven articles fulfilled the inclusion criteria. Five out of seven articles showed association between HRV and burnout score, while two articles showed no association between HRV and burnout score. Discussion: In the presence of stress, the autonomic nervous system activates the amygdala and hypothalamus, which subsequently triggers response from the adrenal gland to produce noradrenaline, which in turn affects the autonomic nervous system. A low HRV signifies inflexibility of the sympathetic and parasympathetic nervous system. Contradicting results may be caused by difference in sample and HRV confounding factors such as difference of physical activity, exercise, underlying disease, medication. Conclusion: There is an association between burnout score and HRV, which implies the presence of neuro-autonomic dysfunction in burnout patients. Further research is needed to rule out confounding factors.
Inhibitory Effects of Petai Peel Extract Gel on Tyrosinase and TRP1 Gene Expression in UVB-Exposed Mouse Skin
Authors: Hutabarat Nenny Lynda Caroline , Subchan Prastyowati , Putra Agung , Amalina Nur Dina , Sitompul Faya Nuralda
Published: February 2025

Background: UVB irradiation can induce the formation of Reactive Oxygen Species (ROS), which causes the activation of melanin synthesis through the activation of tyrosinase and tyrosinase-related protein-1 (TRP1). Secondary metabolites in stink bean peel extract inhibit ROS production due to exposure to UVB rays. This study aims to determine the effect of administering stink bean peel extract gel on the expression of the tyrosinase and TRp1 genes in mouse skin tissue exposed to UVB. Method: The research design was a posttest-only control group with a completely randomized design method. The samples studied were 24 mice exposed to UVB light with a wavelength of 302 nm and an energy of 390mJ/cm2/day 3 times a week for 2 weeks. This research was carried out in four groups: the healthy group, the negative control group, treatment 1 (T1) with 10% stink bean peel extract gel, and treatment 2 (T2) with 20% stink bean peel extract gel. Tyrosinase and TRP1 gene expression were analyzed using qRT-PCR. Results: qRT-PCR analysis showed that there was a significant decrease in tyrosinase and TRP1 gene expression between groups T1 (tyrosinase 3,19±2,12 and TRP1 4,96±3,42) and T2 (tyrosinase 0,65±0,44 and TRP1 2,22±1,18) compared to negative control (tyrosinase 17,92±3,77 and TRP1 35,91±4,52). Conclusion: The administration of stink bean peel extract gel has shown promising results in reducing the expression of tyrosinase and TRP1 genes in hyperpigmentation mice exposed to UVB light. This suggests that stink bean peel extract could be a safe and effective therapeutic approach for preventing UVB-induced hyperpigmentation.
Investigating the Impact of Artistic Activism on Health Policy
Authors:   Faculty of Medicine Kampala International University Uganda, Bina K. Nalongo
Published: February 2025

This paper investigates the intersection of artistic activism and health policy, focusing on how artistic interventions influence policy debates, address health disparities, and foster societal change. By examining historical and contemporary case studies, the paper demonstrates the capacity of artistic activism to challenge social norms, mobilize communities, and inform policy decisions. It emphasizes the unique ability of art to humanize complex issues, engage diverse audiences, and serve as a catalyst for inclusive policymaking. Through methodological assessments, the paper highlights key success factors, potential pitfalls, and the evolving role of interdisciplinary collaborations in advancing health equity. The findings underscore the need for robust frameworks to evaluate the impact of art-driven initiatives on health policy and advocate for expanded research and practice in this domain.

Keywords: Artistic Activism, Health Policy, Social Change, Public Health Advocacy, Interdisciplinary Collaboration.
The Importance of Mentorship in Educational Administration
Authors:   Faculty of Education, Kampala International University, Uganda, Kashaka Nyiramukama Diana
Published: February 2025

Mentorship in educational administration is a critical strategy for professional growth, leadership development, and institutional success. In a complex and evolving educational landscape, mentorship provides essential support, guidance, and practical knowledge that bridge the gap between theory and practice. This paper examines the roles, benefits, and challenges of mentorship in fostering effective educational leaders. Key themes include the nurturing of professional skills, the reduction of isolation among new administrators, and the role of mentors in creating a collaborative, trust-based leadership environment. Effective mentorship programs strengthen professional confidence, decision-making, and organizational cohesion. Recommendations focus on institutional investments in structured mentorship programs, mentor training, and the adoption of flexible frameworks to ensure sustainable success. The study underscores mentorship as a transformative practice essential for building resilient educational leadership.

Keywords: Mentorship, Educational Administration, Leadership Development, Professional Growth, Administrator Support
Ethical Dilemmas in Legal Advertising
Authors:   Faculty of Business, Kampala International University, Uganda, Amina G. Kagaba
Published: February 2025

Legal advertising is a vital tool for attorneys to connect with potential clients and ensure access to justice. However, it presents numerous ethical challenges, balancing business goals with professional responsibilities. This paper examines the evolution of legal advertising, from its historical restrictions to the contemporary landscape shaped by digital marketing and social media. The ethical dilemmas discussed include truth in advertising, conflicts of interest, deceptive practices, and the tension between representation and profit. Through a regulatory framework analysis and real-world case studies, this paper underscores the importance of adhering to ethical principles to maintain public trust and the integrity of the legal profession. Recommendations emphasize transparent, truthful, and client-centered advertising strategies to align with both professional standards and societal expectations.

Keywords: Legal Advertising, Ethical Challenges, Attorney Marketing, Truth in Advertising, Deceptive Practices, Conflicts of Interest.
What Did The Early Church Think About Fasting?
Authors: Wagen Corin
Published: February 2025

(This is a bit of a departure from my usual chemistry-focused writing.)
Ep 22 - The Nobel Turing Challenge: A New Dawn for Discovery
Authors: Titus Alexander
Published: February 2025

I’ve always believed that the process of discovery is as fascinating as the outcomes it yields. It’s not just about the eureka moments but the intricate web of questions, failures, and persistence that lead us there. I have been a fan of the concept of the Nobel Turing Challenge for a while, an idea I first read about in a paper by Hiroaki Kitano.
Marcha Federal del Orgullo antifascista y antirracista
Authors: Tzovaras Bastian Greshake
Published: February 2025

March in Rosario, Argentina on February 1st, 2025
New paper: review of the supernumerary muscles of the human leg and foot
Authors: Wedel Matt
Published: February 2025

I have a new paper out: Ramnani, A.S., Landeros, J.T., Wedel, M., Moellmer, R., Wan, S., Shofler, D.W. 2025. Supernumerary muscles in the leg and foot: A review of their types, frequency, and clinical implications. Journal of the American Podiatric Medical Association 114(6): 9pp.
In silico and in vivo studies of hypoglycemic activity of novel thienopyridine and dihydropyridine derivatives
Authors: S. Ketova Elena , Yu. Bibik Elena , V. Myazina Anna , G. Krivokolysko Sergey
Published: February 2025

Purpose of the study. We aimed to find and study in silico and in vivo novel thienopyridine and dihydropyridine derivatives with hypoglycemic activity. Materials and methods. Three derivatives of thienopyridine and dihydropyridine with potential hypoglycemic effect were selected from 350 novel cyanothioacetamide derivatives synthesized by the authors in the “ChemEx” Research Laboratory using virtual bioscreening based on SwissTargetPrediction software, and their oral administration safety was assessed. During the experimental study conducted on 72 mature male Wistar rats, we modeled hyperglycemia in the animals by means of high-fat diet and dexamethasone load, then we performed pharmacological correction of metabolic disorders with the novel compounds and comparison drugs - Metformin, Vildagliptin. Upon withdrawal of animals from the experiment, blood was sampled for further biochemical investigation and determination of glucose concentration, ALT, AST, total bilirubin, triglycerides, and total blood cholesterol levels. Results. The results of molecular docking showed that the novel compounds with the codes AZ-383, AZ-257, and AZ-020 have putative effects on biotargets with potential for the correction of hyperglycemia and positive impact on lipid metabolism and liver function. In addition, these compounds have a good safety profile when administered orally. In the in vivo study, compounds AZ-383, AZ-257, and AZ-020 were found to have hypoglycemic activity and associated hepatoprotective and hypolipidemic properties. Conclusions. Novel derivatives of thienopyridine and dihydropyridine showed hypoglycemic activity in the experiment following metabolic disorder modeling in animals. This corresponds fully with the biotargets identified in silico for these compounds. Pharmacological activity of compounds with the codes AZ-383, AZ-257, and AZ-020, as well as their oral administration safety confirm the high relevance of further study.
Identification of pathogen infected rice paddy field in West Papua, Indonesia based on ITS rDNA
Authors: Kellen Yustina , Abbas Barahima , Martinus Reinhard Ruimassa Reymas , Tuminem Tuminem
Published: February 2025

Pathogens infect rice plants during vegetative and generative growth and can cause a decrease in rice production were estimated Root-knot nematode (RKN). This study aimed to identify pathogen infected rice paddy field in West Papua Province and to reveal genetic relationships among isolates using the ITS rDNA sequence data. The RKN isolates were isolated from rice plantations centre in West Papua Province and other RKN rDNA sequences were retrieved from the GenBank. Based od ITS rDNA sequence data, RKN infects rice faddy field in West Papua Province were identified species of Meloidogyne graminicola and were observed four genotypes, namely genotype-1 for Prafi-1 isolates, genotype-2 for Prafi-2 isolates, genotype-3 for Sidey isolates, and genotype-4 for Oransbary isolates. M. garminicola is closely related with M. garminicola from Thailand-1 (MT271020.1), Thailand-2 (MT271021.1), Nepal-1 (DQ909035.1), Nepal-3 (DQ909038.1), and Nepal-7 (DQ909049.1) with genetic distance range from 0.28 to 2.14 and being in the same sub-clades. This pest is first reported infects rice paddy field in West Papua Province and need awareness so that unspread to any rice faddy field.
KNOWLEDGE, ATTITUDE AND PRACTICE (KAP) ANALYSIS OF EWALLET USERS IN CHENNAI, TAMIL NADU, INDIA
Authors: Kumar G. , Christy Maria , Raja A Vincent , Pasha Sukrishnalall
Published: February 2025

This study explores how many people in Chennai, Tamil Nadu know about digital wallets as India moves towards a cashless economy. Surveying 300 individuals, we looked into their preferred e-wallets and reasons behind their choices. The results reveal that more people are using e-wallets for daily transactions and find them convenient. Notwithstanding, some users express reservations about the security and ease of use of ewallets. To enhance their services, we therefore recommend that e-wallet companies address these concerns. The study also finds varying levels of awareness of e-wallets among different age groups in Chennai, Tamil Nadu. The results from the Chi-square test revealed that the relationship between age group and the awareness of digital wallet is statistically significant.
Factors Influencing Nutrition Status in Toddlers in Work Areasuptdcommunity Health Center Karang Tumaritis Nabire District
Authors: Deborah Deba  , Nur Susan Iriyanti Ibrahim  , Gandhi Pratama
Published: February 2025

Background: Malnutrition including undernutrition is a major health problem for toddlers. Data from the Nabire District Health Office shows the number of cases of toddlers experiencing undernutrition.in Nabire Regency is 177 toddlers in 2023. Data from the UPTD Karang Tumaritis Health Center shows that toddlers who experience malnutrition in the Working Area of ??the UPTD Karang Tumaritis Health Center, Nabire Regency in 2023 are 26 toddlers. Objective: The purpose of this study was to determine the factors that influence Malnutrition Status in Toddlers in Nabire. Method: The research design used was case control with purposive random sampling technique. The study population wasall toddlers in the Working Area of ??UPTD Karang Tumaritis Health Center, Nabire Regency. The sample used was 110 toddlers. While the respondents were mothers of toddlers. Sampling was carried out by accidental sampling from 208 toddlers. Data collection was carried out in the monthMarch to May 2024 includes dataprimary and secondary.Results: Data processing was carried out using a computer with the SPSS (Program for Social Scene) version 16.1 application with the chi-square test. The results of statistical analysis showed that the factors that influence malnutrition are infectious diseases (large p-value = 0.00), immunization status (p-value = 0.00), history of exclusive breastfeeding (p-value = 0.00), and unrelated factors, namely the level of maternal education (p-value = 0.25). Conclusion: Factors that influence malnutrition are infectious diseases, immunization status, history of exclusive breastfeeding. Suggestion: Early detection and prevention of malnutrition in children must be improved in the child growth and development monitoring program.
The Relationship between Pregnancy Spacing and Parity with Incidence of Chronic Energy Deficiency (CED) in Pregnant Women
Authors: Usi Lanita  , Sri Astuti Siregar  , Kasyani Kasyani
Published: February 2025

One of the nutritional problems in pregnant women that is important to address is Chronic Energy Deficiency (CED). CED can cause anaemia, bleeding, the mother does not gain weight normally, and contracting infectious diseases. This study aims to determine the relationship between pregnancy spacing and parity with the incidence of CED in pregnant women. Quantitative research with cross-sectional design. The study was conducted on pregnant women in Jambi City in 2024, totalling 98 people. Data analysis using Chi Square test. The results showed that there was a significant relationship between pregnancy distance (0.034) with the incidence of CED in pregnant women. There is no relationship between parity (0.340) with the incidence of CED in pregnant women. It is concluded that there is a relationship between pregnancy spacing and the incidence of SEZ in pregnant women. It is expected for pregnant women to set a safe pregnancy distance that is above 2 years from the previous pregnancy, in addition it is also recommended to the Health Office and Puskesmas to often educate to increase the knowledge of pregnant women about the prevention and treatment of CED.
Asuhan Kebidanan Continuity of Care pada Ny. D dengan Penerapan Pijat Oksitosin dan Minyak Zaitun
Authors: Hida Febrina  , Hikmah Ifayanti  , Hellen Febrianti
Published: February 2025

Continuity of care (COC) or sustainable care is the care provided by a midwife to clients or patients from pregnancy, childbirth, the puerperium, newborn care, and family planning. This study aimed to provide continuity of midwifery care for a primigravida pregnant woman, Mrs. D, at a midwife practice. A case study method was used. The subject was Mrs. D, G1P0A0. Data collection was carried out from September to December 2023. The results showed that during pregnancy Mrs. D complained of sleep difficulties, during childbirth there was bloody show, in the puerperium period milk production was insufficient, the baby had diaper rash, and for family planning she wanted to use the pill. Interventions provided were health education on third trimester discomforts, normal childbirth management with 60 steps of APN, oxytocin massage, and olive oil for the baby. In conclusion, continuity of midwifery care was provided for Mrs. D with oxytocin massage and olive oil interventions. Milk production increased and the baby's diaper rash reduced.
Hubungan Tingkat Kecemasan dan Tingkat Stres dengan Kejadian Insomnia pada Mahasiswa Fikes yang Menjalani Tugas Akhir di Universitas Abulyatama
Authors: Nurul Nazirah  , Syukriadi Syukriadi  , Nurul Amna
Published: February 2025

Nowadays, insomnia symptoms are experienced by many people, especially those who are in the final semester and are working on their final assignments. The common causes of insomnia are anxiety and stress. Therefore, this study tries to investigate the correlation between anxiety and stress levels and the incidence of insomnia among college students completing the thesis at the Health Sciences Faculty of Universitas Abulyatama. This study employs an analytical design with a cross-sectional approach involving 134 college students as the sample chosen using a total sampling technique. The data was analyzed using univariate and bivariate data with the Chi-Square test. The result reveals that from 134 respondents, the majority experienced sleep disorder indicated by 51 students (38, 1%). On the anxiety variable, the majority experienced severe anxiety 36 students (26, 9%), and the variable of stress level indicated that the majority experienced moderate stress 63 students (47%). Based on the Chi-Square test, there is a correlation between the anxiety variable (p=0,008) and stress level variable (p=0,005) towards the incidence of insomnia in final-year students. This study concludes that the incidence of insomnia in final-year students is influenced by anxiety and stress. This study recommends campuses provide information consultation on insomnia, such as health socialization through social media on how to deal with anxiety and stress management.