bluuebunny/crossref_metadata_2025 huggingface dataset:
Midwives in Health Sciences as a Sociocultural Phenomenon: Legislation, Training and Health (XV–XVIII Centuries)
Authors: Espina-Jerez Blanca , Romera-Álvarez Laura , Cotto-Andino Maylene , Aguado Mercedes de Dios , Siles-Gonzalez José , Gómez-Cantarino Sagrario
Published: September 2022

Background and Objectives: The first inquisitorial processes were developed against Muslims and Jews. Then, they focused on women, especially those dedicated to care. Progressively, they were linked to witchcraft and sorcery due to their great assistance, generational and empirical knowledge. The health historiography of the 15th–18th centuries still has important bibliographic and interpretive gaps in the care provided by women. The main objective was to analyse the care provided by midwives in the legislative and socio-sanitary context of New Castile, in the inquisitorial Spain of the 15th–18th centuries. Materials and Methods: A historical review was conducted, following the Dialectical Structural Model of Care. Historical manuals, articles and databases were analysed. Results: The Catholic Monarchs established health profession regulations in 1477, including midwives. However, all legislations were annulled by Felipe II in 1576. These were not resumed until 1750. Midwives assumed a huge range of functions in their care commitment (teaching, care and religion) and were valued in opposing ways. However, many of them were persecuted and condemned by the Inquisition. They used to accompany therapeutic action with prayers and charms. Midwives were usually women in a social vulnerability situation, who did not comply with social stereotypes. Conclusions: Midwives, forerunners of current nursing and health sciences, overcame sociocultural difficulties, although they were condemned for it. Midwives achieved an accredited title, which was taken from them for two centuries. They acted as health agents in a society that demanded them while participating in a “witch hunt”.
Molecular Pathogenesis of Endotheliopathy and Endotheliopathic Syndromes, Leading to Inflammation and Microthrombosis, and Various Hemostatic Clinical Phenotypes Based on “Two-Activation Theory of the Endothelium” and “Two-Path Unifying Theory” of Hemostasis
Authors: Chang Jae C.
Published: September 2022

Endotheliopathy, according to the “two-activation theory of the endothelium”, can be triggered by the activated complement system in critical illnesses, such as sepsis and polytrauma, leading to two distinctly different molecular dysfunctions: (1) the activation of the inflammatory pathway due to the release of inflammatory cytokines, such as interleukin 6 and tumor necrosis factor-α, and (2) the activation of the microthrombotic pathway due to the exocytosis of hemostatic factors, such as ultra-large von Willebrand factor (ULVWF) multimers and FVIII. The former promotes inflammation, including inflammatory organ syndrome (e.g., myocarditis and encephalitis) and multisystem inflammatory syndrome (e.g., cytokine storm), and the latter provokes endotheliopathy-associated vascular microthrombotic disease (VMTD), orchestrating thrombotic thrombocytopenic purpura (TTP)-like syndrome in arterial endotheliopathy, and immune thrombocytopenic purpura (ITP)-like syndrome in venous endotheliopathy, as well as multiorgan dysfunction syndrome (MODS). Because the endothelium is widely distributed in the entire vascular system, the phenotype manifestations of endotheliopathy are variable depending on the extent and location of the endothelial injury, the cause of the underlying pathology, as well as the genetic factor of the individual. To date, because the terms of many human diseases have been defined based on pathological changes in the organ and/or physiological dysfunction, endotheliopathy has not been denoted as a disease entity. In addition to inflammation, endotheliopathy is characterized by the increased activity of FVIII, overexpressed ULVWF/VWF antigen, and insufficient ADAMTS13 activity, which activates the ULVWF path of hemostasis, leading to consumptive thrombocytopenia and microthrombosis. Endothelial molecular pathogenesis produces the complex syndromes of inflammation, VMTD, and autoimmunity, provoking various endotheliopathic syndromes. The novel conceptual discovery of in vivo hemostasis has opened the door to the understanding of the pathogeneses of many endotheliopathy-associated human diseases. Reviewed are the hemostatic mechanisms, pathogenesis, and diagnostic criteria of endotheliopathy, and identified are some of the endotheliopathic syndromes that are encountered in clinical medicine.
Introducing Polar Groups in Porous Aromatic Framework for Achieving High Capacity of Organic Molecules and Enhanced Self-Cleaning Applications
Authors: Yan Zhuojun , Qiao Yimin , Sun Qiqi , Cui Bo , Feng Bin , Bu Naishun , Chu Kuo , Ruan Xianghui , Yuan Ye , Yang Yajie , Xia Lixin
Published: September 2022

Due to the frequent oil/organic solvent leakage, efficient oil/water separation has attracted extensive concern. However, conventional porous materials possess nonpolar building units, which reveal relatively weak affinity for polar organic molecules. Here, two different polarities of superhydrophobic porous aromatic frameworks (PAFs) were synthesized with respective orthoposition and paraposition C=O groups in the PAF linkers. The conjugated structure formed by a large number of alkynyl and benzene ring structures enabled porous and superhydrophobic quality of PAFs. After the successful preparation of the PAF solids, PAF powders were coated on polyester fabrics by a simple dip-coating method, which endowed the resulting polyester fabrics with superhydrophobicity, porosity, and excellent stability. Based on the unique structure, the oil/water separation efficiency of two superhydrophobic flexible fabrics was more than 90% for various organic solvents. Polar LNU-26 PAF showed better separation performance for the polar oils. This work takes the lead in adopting the polar groups as building units for the preparation of porous networks, which has great guiding significance for the construction of advanced oil/water separation materials.
Antioxidant, Antibacterial, and Antifungal Activities of the Ethanolic Extract Obtained from Berberis vulgaris Roots and Leaves
Authors: El-Zahar Khaled Meghawry , Al-Jamaan Mubarak Eid , Al-Mutairi Faisal Rasmi , Al-Hudiab Abdallah Mohamed , Al-Einzi Mohamed Saleh , Mohamed Ahmed Abdel-Zaher
Published: September 2022

This work assessed the phenolic and flavonoid components and their antioxidant, antifungal, and antibacterial effects in the ethanolic extract of barberry leaf and roots. The antibactericidal activity of root and leaf extracts against pathogenic bacteria was tested using agar diffusion and microdilution broth production for the lowest inhibitory concentration (MIC). Berberis vulgaris root and leaf extracts inhibited Staphylococcus aureus ATCC9973, Escherichia coli HB101, Staphylococcus enteritis, and Escherichia coli Cip812. The disc assay technique was used to assess the bactericidal activity of the extracts versus both pathogenic Gram-positive and Gram-negative strains. Hydro alcoholic extract was more effective against bacterial than fungal strains. The results showed that Berberis vulgaris leaf and roots extract had similar antifungal activities. Berberis vulgaris root extract inhibited the mycelial growth of Penicillium verrucosum, Fusarium proliferatum, Aspergillus ochraceous, Aspergillus niger, and Aspergillus flavus. Berberis vulgaris root extract has excellent antioxidant, antibacterial, and antifungal effects. Berberis vulgaris exhibited antimicrobial activity in vitro, and MIC showed that Berberis vulgaris parts efficiently affected pathogens in vitro. In conclusion, both Berberis vulgaris roots and leaves have considerable antibacterial activity and can be used as a source of antibacterial, antioxidant, and bioactive compounds to benefit human health.
Induction of the Prenylated Stilbenoids Arachidin-1 and Arachidin-3 and Their Semi-Preparative Separation and Purification from Hairy Root Cultures of Peanut (Arachis hypogaea L.)
Authors: Sharma Amit , Gajurel Gaurav , Ahmed Izzeldin , Roedel Krystian , Medina-Bolivar Fabricio
Published: September 2022

Prenylated stilbenoids such as arachidin-1 and arachidin-3 are stilbene derivatives that exhibit multiple pharmacological activities. We report an elicitation strategy using different combinations of cyclodextrin, hydrogen peroxide, methyl jasmonate and magnesium chloride to increase arachidin-1 and arachidin-3 production in peanut hairy root cultures. The treatment of hairy root cultures with cyclodextrin with hydrogen peroxide selectively enhanced arachidin-1 yield (132.6 ± 20.4 mg/L), which was 1.8-fold higher than arachidin-3. Similarly, cyclodextrin combined with methyl jasmonate selectively enhanced arachidin-3 yield (178.2 ± 6.8 mg/L), which was 5.5-fold higher than arachidin-1. Re-elicitation of the hairy root cultures further increased the levels of arachidin-1 and arachidin-3 by 24% and 42%, respectively. The ethyl acetate extract of the culture medium was consecutively fractionated by normal- and reversed-phase column chromatography, followed by semi-preparative HPLC purification on a C18 column to yield arachidin-1 with a recovery rate of 32% and arachidin-3 with a recovery rate of 39%, both at higher than 95% purity. This study provided a sustainable strategy to produce high-purity arachidin-1 and arachidin-3 using hairy root cultures of peanuts combined with column chromatography and semi-preparative HPLC.
Oxidized Biomass and Its Usage as Adsorbent for Removal of Heavy Metal Ions from Aqueous Solutions
Authors: Condurache Bogdan-Constantin , Cojocaru Corneliu , Samoila Petrisor , Cosmulescu Susana Felicia , Predeanu Georgeta , Enache Andra-Cristina , Harabagiu Valeria
Published: September 2022

Nowadays, very coarse wool fibers are considered waste biomass and are discarded at random or burned. Therefore, it is of actual interest to valorize coarse wool fibers as utile products. In this sense, we report herein an environmentally-friendly process for the preparation of a new material based on oxidized wool fibers and designed for efficient adsorption of heavy metals from wastewater. The morphology and the structure of the obtained product were characterized by scanning electron microscopy (SEM) coupled with an X-ray energy-dispersive module (EDX) and by Fourier-transform infrared spectroscopy (FTIR). Likewise, the performances of the oxidized wool fibers for the adsorption of heavy metal cations (Cu2+, Cd2+, Pb2+) from aqueous solutions were tested. The adsorption kinetics data were analyzed by applying the pseudo-first-order (PFO) and pseudo-second-order (PSO) kinetic models. The equilibrium of the adsorption process was investigated by using the Freundlich and Langmuir isotherm models. According to the Langmuir isotherms registered at 300 K, the maximum adsorption capacities of the oxidized wool were found to increase from Cu2+ (9.41 mg/g) and Cd2+ (10.42 mg/g) to Pb2+ (30.71 mg/g). Consequently, the removal efficiency of metal ions was found to vary in the range of 96.8–99.7%. The thermodynamic parameters (e.g., enthalpy, entropy, and Gibbs free energy) were calculated and discussed.
Propolis: Its Role and Efficacy in Human Health and Diseases
Authors: Zullkiflee Nadzirah , Taha Hussein , Usman Anwar
Published: September 2022

With technological advancements in the medicinal and pharmaceutical industries, numerous research studies have focused on the propolis produced by stingless bees (Meliponini tribe) and Apis mellifera honeybees as alternative complementary medicines for the potential treatment of various acute and chronic diseases. Propolis can be found in tropical and subtropical forests throughout the world. The composition of phytochemical constituents in propolis varies depending on the bee species, geographical location, botanical source, and environmental conditions. Typically, propolis contains lipid, beeswax, essential oils, pollen, and organic components. The latter include flavonoids, phenolic compounds, polyphenols, terpenes, terpenoids, coumarins, steroids, amino acids, and aromatic acids. The biologically active constituents of propolis, which include countless organic compounds such as artepillin C, caffeic acid, caffeic acid phenethyl ester, apigenin, chrysin, galangin, kaempferol, luteolin, genistein, naringin, pinocembrin, coumaric acid, and quercetin, have a broad spectrum of biological and therapeutic properties such as antidiabetic, anti-inflammatory, antioxidant, anticancer, rheumatoid arthritis, chronic obstruct pulmonary disorders, cardiovascular diseases, respiratory tract-related diseases, gastrointestinal disorders, as well as neuroprotective, immunomodulatory, and immuno-inflammatory agents. Therefore, this review aims to provide a summary of recent studies on the role of propolis, its constituents, its biologically active compounds, and their efficacy in the medicinal and pharmaceutical treatment of chronic diseases.
Detailed Structural Characterization of Oxidized Sucrose and Its Application in the Fully Carbohydrate-Based Preparation of a Hydrogel from Carboxymethyl Chitosan
Authors: Kono Hiroyuki , Noda Junki , Wakamori Haruki
Published: September 2022

Oxidized sucrose (OS) is a bio-based cross-linking agent with excellent biological safety and environmental non-toxicity. However, the precise structure of OS has not been elucidated owing to its structural complexity and low purity. Accordingly, in this study, complete chemical shift assignments were performed by applying various nuclear magnetic resonance techniques, which permitted the structural and quantitative characterization of the two main OS products, each of which contained four aldehyde groups. In addition, we investigated the use of OS as a cross-linking agent in the preparation of a hydrogel from carboxymethyl chitosan (CMC), one of the most popular polysaccharides for use in biomedical applications. The primary amine groups of CMC were immediately cross-linked with the aldehyde groups of OS to form hydrogels without the requirement for a catalyst. It was found that the degree of cross-linking could be easily controlled by the feed amount of OS during CMC hydrogel preparation and the final cross-linking degree affected the thermal, swelling, and rheological properties of the obtained hydrogel. The results presented in this study are therefore expected to be applicable in the preparation of fully carbohydrate-based hydrogels for medical and pharmaceutical applications.
Dynamic Path Planning for Forklift AGV Based on Smoothing A* and Improved DWA Hybrid Algorithm
Authors: Wu Bin , Chi Xiaonan , Zhao Congcong , Zhang Wei , Lu Yi , Jiang Di
Published: September 2022

FAGV is a kind of heavy equipment in the storage environment. Its path needs to be simple and smooth and should be able to avoid sudden obstacles in the process of driving. According to the environmental characteristics of intelligent storage and the task requirements of FAGV, this paper proposed a hybrid dynamic path planning algorithm for FAGV based on improved A* and improved DWA. The improved A* algorithm can plan the global optimal path more suitable for FAGV. The improved evaluation function of DWA can ensure that the local path of FAGV is closer to the global path. DWA combines the rolling window method for local path planning to avoid sudden unknown static and dynamic obstacles. In addition, this paper verifies the effectiveness of the algorithm through simulation. The simulation results show that the algorithm can avoid obstacles dynamically without being far away from the global optimal path.
Endogenous, Regime-Switching Hedonic Estimation of Commercial Waterway Water Quality Impact on Home Values in the Alabama Black Belt
Authors: Affuso Ermanno , Cummings John Reid , Beebe Donald Alex , Schultze Steven R.
Published: September 2022

We are the first researchers to investigate the impact of the water quality of a commercial marine waterway on the housing market. We use housing data for properties in proximity to the major waterways and minor tributaries of the Gulf Intracoastal Waterway in the Alabama Black Belt. Research shows a positive relationship between water quality and the value of waterfront properties. We use waterway impairment as a proxy to measure water quality to conduct a counterfactual analysis based on a unique endogenous regime-switching hedonic price model. We find significant empirical evidence that properties in proximity to the Black Belt’s major waterways could depreciate by approximately 22% compared to the counterfactual case of properties located on or near minor tributaries. A possible implication might be that homeowners prefer properties on or near minor tributaries of the Alabama Black Belt because of perceptions that the water quality is better than on major commercial waterways.
How Much Does the Board Composition Matter? The Impact of Board Gender Diversity on CEO Compensation
Authors: Nawaz Tasawar
Published: September 2022

The notion that female directors are better disposed to protect shareholders’ interests has brought boardroom gender diversity into the limelight. Echoing these emerging trends, this paper analyzes the relationship between board gender diversity, i.e., proportion of female directors on the corporate board, and Chief Executive Officer’s (CEO) compensation. Consistent with conjecture, the analysis suggests that large and diversified corporate boards are the main determinants of CEO compensation. Furthermore, longer-tenured CEOs who also serve as board chairperson receive higher total compensation and bonuses than their counterparts do. Into the bargain are corporate performance proxied by return of assets (ROA) and firm attributes, i.e., firm size and institutional ownership, which have divergent but direct implications for CEO compensation.
Tachyons as a Consequence of Light-Cone Reflection Symmetry
Authors: Chodos Alan
Published: September 2022

We introduce a new symmetry, light-cone reflection (LCR), which interchanges timelike and spacelike intervals. Our motivation is to provide a reason, based on symmetry, why tachyons might exist, with emphasis on application to neutrinos. We show that LCR, combined with translations, leads to a much larger symmetry. We construct an LCR-invariant Lagrangian and discuss some of its properties. In a simple example, we find complete symmetry in the spectrum between tachyons and ordinary particles. We also show that the theory allows for the introduction of a further gauge invariance related to chiral symmetry.
Economic processes and phenomena of agricultural land use based on the theory of marginal productivity and the law of diminishing returns
Authors:   FSBI FNCC VNIIESH, Moscow, Alakoz V.V.
Published: September 2022

The article deals with economic processes and phenomena of agricultural land use, based on the theory of marginal productivity and the law of diminishing returns. Theoretical foundations, initial statistical data, graphically and mathematically substantiated models of economic analysis of production costs and returns in agriculture, and the obtained results provide a solution to the fundamental problem of production efficiency at the micro level, having the maximum possible rate of return, the maximum possible profitability of agricultural activities, geographical features of agricultural land use, the implementation of state land policy taking into account the regional characteristics of agricultural activities, food self-sufficiency and demand in the world food market.
Agriculture in a modern city. The integration of agricultural objects into urban environment
Authors:   State University of Land Management, Moscow, Bykova G. I. , Ivanova E. ,   State University of Land Management, Moscow, Kostochkina O. V. ,   State University of Land Management, Moscow, Golubeva T. P ,   State University of Land Management, Moscow
Published: September 2022

The article reflects the issues of creating harmonious architectural objects in the conditions of urbanization, which implies a symbiosis of nature, architecture and human agricultural activity. A necessary condition for the construction of buildings is the use of modern achievements in the field of technical equipment of structures that ensure the vital activity of plants in them, Recommendations for the inclusion of agricultural objects in the fabric of an urbanized city and buildings in it contribute to the expansion of the importance of this sphere of life.
The topical issues of modern agricultural education
Authors:   State University of Land Management, Moscow, Safonova T.B. , Shirokorad I.I. ,   State University of Land Management, Moscow, Borisova M.V. ,   State University of Land Management, Moscow, Staroverova I.V. ,   State University of Land Management, Moscow, Artemova T.A. ,   State University of Land Management, Moscow
Published: September 2022

The article presents the results of a scientific and theoretical experience of educational technologies in solving urgent problems of modern agricultural education on the basis of the State University of Land Use Planning at the implementation of the Federal State Educational Standard of Higher Education.
Cutaneous clear cell adnexal carcinoma in two dogs: cytological and immunohistochemical evaluation
Authors: BOZKURT Mehmet Fatih , BHAYA Muhammad Nasir , NİŞANCI Alper
Published: September 2022

In this study, cases of cutaneous clear cell adnexal carcinoma were diagnosed on the right forepaw of a 6-year-old female dog and on the right hind paw of an 8-year-old male dog. On the cytological examination, scattered cell groups were seen on the hemorrhagic background, whose cytoplasmic borders could hardly be distinguished. Although the cells showed marked pleomorphism, but were generally oval, round, or spindle-shaped. Anisokaryosis, karyomegaly, and one or more prominent nucleoli were noted in the nuclei. Pseudoinclusions were found in some cell nuclei. Histologically, it was centrally necrotic, expansive growth consisting of lobular areas in the dermis. The neoplastic cells consisted of oval round-shaped epithelioid cells with clear cytoplasm showing marked anisocytosis, anisorkaryosis and karyomegaly. Nuclei were oval or round in shape with prominent nucleoli. Cystic changes and calcified areas in layers (psammoma bodies) were noted in these areas. Few mitoses were found. In the immunohistochemical examination, tumor cells were positive for vimentin, S-100, MART1 (Melan A), and cytokeratin (MNF116) and negative for glial fibrillary acidic protein (GFAP) and smooth muscle actin (SMA). Based on these findings and results, the tumors were diagnosed as canine clear cell adnexal carcinoma. According to the literature review, this is the first case in which we found psammoma bodies and nuclear pseudo inclusions on microscopic examination of canine cutaneous clear cell adnexal carcinoma.
Habilidades Directivas y Desempeño Docente en el Perú
Authors: Muñoz Valera Rosa Esther , Huamán Ramos Dora Marianela , Cárdenas Astete Edgard Ernesto , Pinedo Acero Félix William
Published: September 2022

El objetivo del presente estudio fue determinar la relación entre habilidades directivas y desempeño docente en la institución educativa Herman Busse de la Guerra 2095, Los Olivos, 2021. La investigación se desarrolló enmarcada en un enfoque cuantitativo, nivel correlacional, diseño no experimental transversal. La muestra estuvo conformada por 72 docentes y los instrumentos que se aplicaron para el análisis cuantitativo de los datos fueron dos cuestionarios para medir habilidades directivas y desempeño docente, ambos con un índice de fiabilidad de alfa de Cronbach de 94.8% y 94,5% de fiabilidad respectivamente. Se llegó a la conclusión que existe una relación positiva alta entre habilidades directivas y desempeño docente, con un coeficiente de correlación de Spearman = ,762 y una significación estadística p = 0.000, p < 0.05, en de la Institución Educativa Herman Busse de la Guerra 2095, Los Olivos, 2021.
camino comprensivo en la investigación educativa: Reflexiones dentro de la fenomenología hermenéutica
Authors: González Pérez Francis Carolina
Published: September 2022

El propósito de este artículo es reflexionar acerca del camino metodológico vivido en la experiencia investigativa educativa de la autora desde los postulados fenomenológicos hermenéuticos de Van Manen. El estudio se adscribe a un enfoque cualitativo basado en la comprensión hermenéutica bajo los preceptos metodológicos y procedimentales de una sistematización de experiencias, con base en 3 momentos: génesis textual, develamiento de los temas, comprensión hermenéutica. Los hallazgos se asumen en un espacio de significatividad fugitiva por principio que rehúye de la posibilidad de objetivar el conocimiento emergente de los fenómenos educativos, los cuales parten de una pregunta fenomenológica esencial en espacios de interpretación y comunicación con los versionantes y se reconocen como sujetos personas cuya subjetividad es valorada. Las conclusiones se refieren a la convocatoria de la educación como ciencia humana de ser estudiada con métodos que se deslicen hacia lo subjetivo e intersubjetivo, que den profundidad a las voces de quienes actúan esa realidad y de producir textos fenomenológicos que nos acerquen a la sensibilidad del acto educativo con criterios de calidad propios del método.
Aportes de la psicología social comunitaria para la acción del liderazgo comunitario en Venezuela
Authors: Barreto Gil Gilberto Ramón
Published: September 2022

Se lleva a cabo un ensayo sobre los aportes de la psicología social comunitaria a través de la intervención social desde la perspectiva de varios autores en especial de los esquemas aportados por la psicóloga comunitaria Maritza Montero con el fin de relacionar dichos lineamientos con el diseño de planes de acción comunitaria aplicados en Venezuela. Es así como se puede observar el carácter bilateral de la psicología social al estudiar por un lado la psicología individual desde su relación con los fenómenos sociales y la psicología colectiva. Es así como la psicología comunitaria establece como método la intervención social como forma de llevar a cabo la transformación de las comunidades a través de diferentes enfoques, los cuales deben enlazarse con las políticas públicas, el Estado y los líderes comunitarios para conformar lo que Montero (2010) ha descrito como Consorcio Social a partir del cual se pueden originar planes de acción y programas de beneficio comunitario los cuales deben ser las bases metodológicas para el desarrollo de las agendas comunitarias.
A Nomogram to Identify Hyperkalemia Risk in Patients with Advanced CKD
Authors: Xue Cheng , Zhou Chenchen , Yang Bo , Ye Xiaofei , Xu Jing , Lu Yunhui , Hu Xiaohua , Chen Jia , Luo Xiaoling , Zhang Liming , Mei Changlin , Mao Zhiguo
Published: September 2022

Key Points

Tools for diagnosis or prediction of hyperkalemia in CKD are limited, especially in patients not using RAASi.

This study constructed a convenient nomogram and online calculator to identify the risk of hyperkalemia within 6 months in patients with advanced CKD.

Patients with CKD who are identified as high risk of hyperkalemia by the tool may benefit from intensive monitoring and early triage.

Background

Hyperkalemia is a common and life-threatening complication of CKD. We aimed to develop and validate a nomogram that could identify the risk of hyperkalemia (≥5.5 mmol/L) in patients with CKD.

Methods

A retrospective cohort study was performed in adult patients with predialysis advanced CKD (stages ≥3) in 2020–2021 for the outcome of hyperkalemia within 6 months. The training set was used to identify risk factors of hyperkalemia. Then a nomogram was developed by multivariable logistic regression analysis. C-statistics, calibration curves, and decision curve analysis (DCA) were used, and the model was validated in the internal and two external validation sets.

Results

In total, 847 patients with advanced CKD were included. In 6 months, 28% of patients had hyperkalemia (234 out of 847). Independent risk factors were: age ≥75 years, higher CKD stages, previous event of serum potassium ≥5.0 mmol/L within 3 months, and comorbidities with heart failure, diabetes, or metabolic acidosis. Then the nomogram on the basis of the risk factors adding the use of renin-angiotensin-aldosterone system inhibitors was constructed. The C-statistic of the model was 0.76 (95% CI, 0.70 to 0.78), and was stable in both the internal validation set (0.73; 95% CI, 0.63 to 0.82) and external validation sets (0.88; 95% CI, 0.84 to 0.95 and 0.82; 95% CI, 0.72 to 0.92). Calibration curves and DCA analysis both found good performances of the nomogram.

Conclusion

A feasible nomogram and online calculator were developed and validated to evaluate the risk of hyperkalemia within 6 months in patients with advanced CKD. Patients with CKD and a high risk of hyperkalemia may benefit from intensive monitoring and early triage.
Design of Mobile Learning Content with a Mobile-Based Live Multimedia System
Authors: Amsyar Izwan , Latifah Haznah , Wuisan Dewi
Published: September 2022

With the rise of world progress, information technology and telecommunications to the Internet have become a top priority. These advancements mark a watershed moment in mobile learning, or "mobile learning," as it is known (m-learning). M Learning has some extra learning capacity that can be accessed by anybody, at any time, from anywhere. The issues still exist in m-learning, including a shortage of hardware and platforms required by the system architecture and accessibility. In order to become comfortable for the user, a thorough examination of each component dealing with existing m-learning is also required. This research aims to address the problem by employing multimedia as a material that can provide more precise and detailed information. Multimedia m-learning services necessitate an internet connection, excellent access, and adequate hardware to benefit from the overall bias with good services provided by phones that offer mobile multimedia facilities. The study's primary goal is to create m-learning with multimedia services, and the expected results are a software-based content provider.
EMBRIOGÉNESIS SOMÁTICA EN Heliconia collinsiana GRIGGS
Authors: Hernández-Meneses Eleodoro , López-Peralta María Cristina G. , Estrada-Lun Andrés A. , Valdovinos-Ponce Guadalupe
Published: September 2022

Las heliconias son plantas ornamentales tropicales apreciadas por sus inflorescencias de formas exóticas y colores brillantes. Su cultivo requiere sistemas de propagación como la embriogénesis somática, que permitan clonar genotipos élite y generar suficiente material vegetativo de calidad fitosanitaria certificada. El objetivo de esta investigación fue establecer un protocolo de embriogénesis somática para Heliconia collinsiana y caracterizar histológicamente el origen de los embriones. Secciones transversales de la base de pseudotallos de plantas regeneradas in vitro se establecieron en el medio de Murashige y Skoog (MS) con distintas concentraciones de ácido 2,4-diclofenoxiacético (2,4-D) para inducir la formación de callos. En las etapas de maduración y germinación de los embriones se evaluó el efecto de benciladenina (BA), ácido abscísico (ABA), y en la conversión a plantas, se evaluó la concentración de sales MS. La formación de callos ocurrió en oscuridad con 18 mg L-1 de 2,4-D y 0.5 g L-1 de carbón activado. La multiplicación de callos se obtuvo con 1 o 2 mg L-1 de 2,4-D y 16 h luz. La maduración y germinación de los embriones somáticos se observó con 0.5 mg L-1 de BA, y la conversión y crecimiento de las plantas se logró con la mitad de concentración de sales del medio MS. Los embriones se originaron de masas proembriogénicas conformadas por células pequeñas, isodiamétricas, con núcleos prominentes y citoplasma denso. En la etapa de aclimatación, 95 % de las plantas sobrevivieron en condiciones de invernadero. Este es el primer protocolo de embriogénesis somática novedoso para la multiplicación clonal de esta especie ornamental y establece las bases para futuros estudios en otras especies nativas, cultivares comerciales o híbridos derivados de mejoramiento genético.
CRECIMIENTO ex vitro DE PLÁNTULAS DE Lycaste aromatica (GRAHAM) LINDL.
Authors: Solís-Zanotelli Flor Y. , Hidalgo-Contreras Juan V. , Baltazar-Bernal Obdulia
Published: September 2022

En la micropropagación vegetal la aclimatación es una etapa crucial para promover que en las plantas ocurran cambios morfológicos y fisiológicos para su adaptación ex vitro. El objetivo del presente estudio fue evaluar la supervivencia y desarrollo de plántulas de Lycaste aromatica (Graham) Lindl. obtenidas en dos sistemas de micropropagación (medio semisólido y medio líquido en biorreactor de inmersión por gravedad, BIG). Las plantulas se establecieron en sustratos diferentes (peat moss Premier® o musgo Sphagnum chileno) y recibieron diferentes fungicidas (PHC T-22®, Captan Plus® y Ridomil Bravo® 81, y plantas que no recibieron aplicación) en un diseño experimental completamente al azar con arreglo factorial 2 × 2 × 4, resultando 16 tratamientos. Durante 28 semanas de aclimatación las plantas estuvieron en charolas de plástico transparente con los sustratos correspndientes, en invernadero con temperatura en el intervalo de 20 a 37 °C, irradiancia de 85 μmol m-2 s-1 y 70 % de humedad relativa. Los resultados mostraron que las plantas tuvieron diferencias significativas en supervivencia y número de brotes debido al sistema de micropropagación en que se obtuvieron, mientras que los sustratos influyeron en la supervivencia y clorofila total en hojas. Las plantas obtenidas en medio semisólido y establecidas en sustrato musgo Sphagnum chileno sobrevivieron en proporción del 88 al 100 %. Las plantas obtenidas en el sistema BIG fueron las más altas, con 7.2 cm. Las plantas obtenidas en medio semisólido y establecidas en peat moss Premier® formaron 1.25 brotes. Por otro lado, las plantas obtenidas en medio semisólido, establecidas en peat moss Premier® con aplicación de fungicida Captan Plus® tuvieron más clorofila total (0.43 mg g-1 de peso fresco foliar). Los fungicidas no indujeron diferencias en la supervivencia de las plantas.
paisaje religioso en un partido rural de la Provincia de Maracaibo, Venezuela, durante el siglo XVIII: La Cañada de Allá Dentro
Authors: Rincón Rubio Luis
Published: September 2022

Se realiza una aproximación a la cultura material en el partido rural La Cañada de Allá Dentro, Provincia de Maracaibo, Venezuela, durante el siglo XVIII a la escala del paisaje religioso. Entendiendo cultura material como la expresión tangible de la cultura, creadora de significados y activa en la constitución de las relaciones sociales, se explora el papel que pudo haber jugado la religión católica en la construcción del paisaje local como un espacio habitado y significado, que activamente producía y reproducía identidades y prácticas sociales. Considerando que para la época una capilla existente en el lugar sería el foco del paisaje religioso, se estudian los aspectos formales de dicha capilla y se propone una hipótesis reconstructiva de la misma con base en fuentes documentales y en la tipología conocida de las edificaciones religiosas en la región.
A Secure Message Passing Method using Multi-Layer Adaptive Video Steganography
Authors:   Computer Science and Engineering, Vinayaka Missions Research Foundation, Salem, India., Dcouth Jeswin Roy , Somasundaram Dr. K ,   Computer Science and Engineering, AVIT, Vinayaka Missions Research Foundation, Chennai, India.
Published: September 2022

Steganography is covert communication of a secret message hidden in a medium passed between the intended sender and receiver with no evidence that the work contains a hidden message. The paper proposes a heuristic approach in steganography to secretly embed message in the cover and make use of the Diffie-Hellman key exchange method to be passed on to a secure channel and to be extracted without being detected. Hence the proposed system is a hybrid crypto stego scehme. The study proposes a new and adaptive steganography method that provides multiple layer of security and adaptiveness in passing secret data which emphasizes on undetectability.
ЯПОН ТИЛИДАН ЎЗБЕК ТИЛИГА ҚИЛИНГАН ТАРЖИМАЛАРДА МАДАНИЙ ТРАНСФЕР ВА СЕМАНТИК ДЕРИВАЦИЯ
Authors: SHAMSIEVA Barnokhon
Published: September 2022

Лингвомаданият фани ривожланиш жараёнида вужудга келган “маданият трансфери” назариясида асос бўлган маданият унсурларининг таржима қилинган асар маданиятида шундайлигича намоён бўлиши эмас, балки уни янги маданиятга оид матнда қандай қурилгани, унинг қабул қилувчи маданиятга мослашиши қизиқтиради ва ўрганилади. Ушбу мақолада маданият трансфери назариясида асос бўлган маданият элементларининг таржима қилинган асар маданияти томонидан қандай қабул қилиниши, уни янги маданиятда яъни таржима матнида қандай қурилгани, қабул қилувчи маданиятга мослашиши таҳлил қилинади. Аслиятдаги руҳиятга оид белгиларнинг таржима матнига кўчиши, бадиий асарда миллий маданиятнинг акс этиши ва унинг таржима матнидаги тасаввур (ассоциация) билан боғлиқ хусусиятларини ёритиш мақоланинг асосий мақсади ҳисобланади. Мақолада таржима қилинган матн таҳлили эквивалентлик ёки ноэквивалентлик, муваффақиятли таржима ёки муваффақиятсиз таржима каби масалаларга тўхталмай, асл нусха ва таржима матни ўртасидаги тафовутлар, ассоциация масалаларига урғу берилади. Чунки, муаллифнинг фикрича, айнан уларда трансфер динамикаси намоён бўлади. Ўзбек тилида амалга оширилган, маданият трансфери назарияси доирасида бадиий матн асосида руҳият трансферига оид таҳлил ҳамда тадқиқотларнинг мавжуд эмаслиги мақоланинг илмий янгилиги ҳамда уникаллигини белгилаб беради.
Relationship of Nursing Service Quality with the Satisfaction Level of Participant Hypertension Patients BPJS at RSUD Dr. H. Soemarno Sosroatmodjo
Authors: Indrawijaya I Ketut , Tasalim Rian , Basit Mohammad
Published: September 2022

The quality of nursing services is one of the factors in the quality of health services which is one of the determining factors for the picture of health services in the community. Satisfaction is a feeling that comes as a result of the service action he receives, after the patient compares it with what he expects. To find out the relationship between the quality of nursing services and the level of satisfaction of patients with hypertension, BPJS participants at RSUD Dr. H. Soemarno Sosroatmodjo. This study uses an analytical survey research method with a cross sectional where each research subject is only observed once and measurements are made on the status of the character or variable of the subject on examination. The sample used was 30 people in the inpatient room at Dr. Hospital. H. Soemarno Sosroatmodjo. Sampling with total sampling technique. Data were analyzed using the Chi-square test. The quality of nursing services is mostly good as many as 16 people (53.3%), most of the respondents are satisfied as many as 18 people (60%), Chi-square test results obtained p value = 0.002. With a p value < (α = 0.05), it can be concluded that the hypothesis is accepted, which means that there is a relationship between the quality of nursing services and the level of satisfaction of hypertensive patients who are BPJS participants at RSUD Dr. H. Soemarno Sosroatmodjo. The conclusion, that there is a relationship between the qualities of nursing services with the level of satisfaction of patients with hypertension BPJS participants at RSUD Dr. H. Soemarno Sosroatmodjo.
The Effectiveness of Semi Fowler Position 30 Degrees and 45 Degrees on Increasing SPO2 and Respiratory Rate of Lung TB Patients: Literature Review
Authors: Padliannor Hifzhi , Riduansyah Muhammad , Mahmudah Rifa’atul , Latifah Hj
Published: September 2022

Pulmonary TB is a disease caused by Mycobacterium tuberculosis which attacks the respiratory system and often decreases SPO2. Interventions that can be done to reduce shortness of breath and increase SPO2 are by giving a semi-fowler position. To determine the effectiveness of the semi-Fowler's position on increasing SPO2 and breathing patterns in pulmonary TB patients. Research design literature review. Journal criteria were screened based on literature titles, abstracts and keywords that had been determined and sourced from Biomed Central, DOAJ, Pubmed, Elsevier, and EBSCO HOST identified through the Population, Intervention, Comparation, Outcomes and Study Design (PICOS) system approach. The number of articles used for this literature is 12 journals. Pulmonary TB patients experienced an increase in SPO2 and a decrease in shortness of breath after being given the semi-Fowler position intervention. The results of the analysis showed the effectiveness of the semi-Fowler position to increase SPO2 and reduce shortness of breath in pulmonary TB patients. Health facilities can provide interventions regarding the effectiveness of the semi-Fowler's position to increase SPO2 and reduce shortness of breath, besides that it can also be used as a nursing care intervention program in pulmonary TB patients.
Periodismo emprendedor, un acercamiento a las estructuras organizacionales, el perfil profesional polivalente e interdisciplinario y la innovación periodística de medios digitales del sur de Sinaloa
Authors: Lincoln Strange Reséndiz Isabel Lincoln Strange Reséndiz , Vega Astorga Miriam Josefina
Published: September 2022

Con el objetivo de evaluar las estructuras organizacionales y la calidad del periodismo emprendedor del sur de Sinaloa, se realizó un estudio cuantitativo a través de una encuesta a periodistas de medios digitales emprendidos en Mazatlán y Escuinapa, para conocer las dinámicas de consolidación de los espacios informativos digitales en el ecosistema mediático de la región; algunas de las variables analizadas fueron el número de integrantes, el perfil profesional y la innovación periodística de dichos espacios. Como sustento teórico se retomaron premisas de la teoría organizacional y el Newsmaking; mientras que el análisis de datos se realizó a través del software SPSS. Los resultados obtenidos indican que, si bien las estructuras organizacionales pequeñas no impactan en la consolidación de los medios emprendidos, la necesidad de perfiles polivalentes e interdisciplinarios y la falta de propuestas innovadoras, podrían influir en la calidad periodística y con ello en la credibilidad y consolidación de los medios a largo plazo.
Aproximaciones interdisciplinarias de la violencia a las mujeres con relación a la interacción comunicativa
Authors: Padilla Barrios Juan Ricardo
Published: September 2022

Este artículo es resultado de una investigación documental desde perspectiva teóricas interdisciplinarias sobre el poder y la violencia social en autores canónicos para vincularlo con la interacción comunicativa con el objetivo de analizar estudios del poder como una herramientadetonadora de violencias estructurales para reconocer su presencia en el statu quo. Así, se contextualiza el tratamiento de la violencia a las mujeres en los marcos legales, sociales, culturales. Entre los principales hallazgos se encontró que la violencia estructural que viven las mujeresrequiere abordajes interdisciplinarios complementarias para explicar el fenómeno de manera transversal encaminado a la transformación social desde una perspectiva comunicativa.
Design of a Strong-Arm Dynamic-Latch based comparator with high speed, low power and low offset for SAR-ADC
Authors: Dutta Sounak
Published: September 2022

Comparators are utilised by Nyquist-rate and oversampling analog to digital converters (ADCs) to accomplish quantization and perhaps sampling. Thus, comparators have a  substantial effect on the speed and accuracy of ADCs. This study provides a revised design for a dynamic-latch-based comparator that achieves the lowest latency, maximum area-efficient realisation, reduced power dissipation, and low offset. The proposed circuit has been designed and simulated using GDPK  45 nm standard CMOS-Process to operate on 100 MHz clock, at  1.2V supply voltage. Design and simulation have been carried  out using CADENCE Virtuoso EDA tool. Compared to the  original design, the PDP was easily reduced by approximately  by 6% with offset voltage reduced by 8 mV without speed trade off. 
Fig rust caused by Phakopsora nishidana in South Africa
Authors: BOSHOFF Willem H.P. , VISSER Botma , BENDER Cornel M. , WOOD Alan R. , ROTHMANN Lisa , WILSON Keith , HAMILTON-ATTWELL Victor , PRETORIUS Zacharias A.
Published: September 2022

Fig rust, caused by Cerotelium fici, was first recorded in South Africa in 1927. Recent observations have revealed high incidence of rust and untimely defoliation of fig trees (Ficus carica) in residential gardens and commercial orchards. Using phylogenetic analysis, the causal organism of a fig rust isolate (PREM63073) collected in 2020 was confirmed as Phakopsora nishidana. Inoculation and microscope studies showed that mulberry plants were immune to P. nishidana isolate PREM63073. Infection of fig leaves occurred through stomata on the abaxial leaf surfaces. Very long germ tubes were observed for P. nishidana, often with no clear contact with the leaf surfaces and an apparent lack of directional growth towards stomata. Inoculated plants from 15 fig cultivars varied in their severity of leaf infection, whereas fruit of the cultivar Kadota developed reddish-brown blemishes without sporulation. Currently, C. fici and P. nishidana are recognised as occurring on F. carica in South Africa. This suggests a need to resolve the worldwide distribution and identity of the rust species involved.
Lipid Disorders among Diabetic Patients: An Observational Study
Authors: Haque Mohammad Mahbubul , Khan Raihan Rotap , Islam Mohammad Mushahidul , Alam Mohammad Shamsul , Ahmed Nur Faysal , Hasan Mohammad Mahmudul
Published: September 2022

Background: Lipid disorder is one of the common disorders which is seen in most of the diabetic patients that causes cardiovascular disorders. The incidence of coronary artery diseases is 3 to 5 times higher in diabetic patients compared to general population. Although this has been demonstrated for the Caucasian population few data are available for Asian Indians and Bangladeshi population. Individuals with diabetes may have several forms of dyslipidemia leading to additive cardiovascular risk of hyperglycemia. The aim of this study was to evaluate the levels of lipid disorder among diabetic patients in Bangladesh. Methods: An observational study was conducted at the Department of Medicine in Sheikh Hasina Medical College Hospital, Jamalpur, Bangladesh during the period from August 2020 to April 2021. One hundred and four (104) diabetic patients were enrolled as study participants in the study. Proper written consents were taken from all the participants before starting data collection. A pre-designed questionnaire was used in patients` data collection. The serum total cholesterol (TC), HDL-cholesterol and triglycerides (TG) were assayed in patients and controls, using standardized assay methods. All data were processed, analyzed and disseminated by MS Office and SPSS version 21 as per need. Result: In this study, we observed that the mean (±SD) TC (mg/dl) of case and control group participants were 208.9±54.6 and 257.4±103.4 respectively where we found significant correlation between the groups (P=0.006). We did not find any correlation between the groups in analyzing TG (mg/dl), HDL (mg/dl) and LDL (mg/dl). In case group the mean (±SD) TG (mg/dl), HDL (mg/dl) and LDL (mg/dl) level were found 216.4±306.0, 39.2±11.0 and 114.8±47.4 respectively. On the other hand, in the control group the mean (±SD) TG (mg/dl), HDL (mg/dl) and LDL (mg/dl) level were found 222.9±124.0, 39.8±6.2 and 122.4±46.3 respectively. Conclusion: In this current study, in analyzing the comparative statuses of lipid profile we found significant correlation between the groups of diabetic and non-diabetic patients in serum total cholesterol component. Although in analyzing other components of lipid we did not get any significant correlation between the groups, we think lipid profiling may be a potential predictor of diabetic patient screening.