bluuebunny/crossref_metadata_2025 huggingface dataset:
Biểu hiện gen fliC cải biến của Salmonella Dublin và tinh sạch flagellin tái tổ hợp
Authors: Vo Viet Cuong , Trinh Van Toan , Le Thi Lan Anh , Dang Thi Viet Huong , Ho Thi Hong Nhung , Nguyen Thi Nhung , Do Thi Huyen , Trinh Khac Sau
Published: May 2023

Flagellin is a potent trigger of innate immune responses that enhance adaptive immune responses. Flagellin has intrinsic adjuvant activity mediated through toll-like receptor (TLR 5) and is an attractive candidate for highly effective vaccine adjuvant. The N-terminal D0-D1 domain of flagellin is required for TLR5 recognition. In the present study, fliC gene from S. Dublin expressed in E. coli BL21 in the fusion form with SUMO protein. The 48 kDa fusion protein of SUMO-flagellin was synthesised in insoluble inclusion body. The overall yield of expressed SUMO - flagellin was 0.6 g/L. The recombinant protein solubilized in 2 M urea then was purified by using Ni-NTA column chromatography with purity about 95.4%. Flagellin will be cleaved from fusion protein and used to develop as a radiation countermeasure.
Tối ưu quy trình phân lập hệ gen virus BK từ mẫu máu, nước tiểu của bệnh nhân sau ghép thận
Authors: Dinh Thi Thu Hang , Dinh Thi Linh , Hoang Xuan Su
Published: May 2023

BK polyomavirus (BKV) is a common opportunistic pathogen in the community, infecting humans in their early life stages, often remaining in a latent state. BK virus-associated nephropathy occurs in 2 to 10% of kidney recipients, and up to 40 to 90% of these patients have permanent loss of graft function due to delay in diagnosis. In the present study, we have successfully optimized the component and thermal cycling for the long-PCR assay to amplify the BKV genome, including middle-concentration samples such as plasma (concentration about 105 copy/ml). We have successfully amplified the BKV genome in 41/50 samples, including 04 plasma and 39 urine samples. The optimized amplification protocol of full-length BKV genome includes the following steps: 1) Extraction of DNA-BKV from plasma and urine samples and quantification of BKV-DNA concentrations to ensure that about 105 copies/ml (plasma) and 107 copies/ml (urine); 2) Each full-length genome reaction in the volume of 50 μl containing 1X Phusion HF master mix (Thermo Scientific, USA); 0.5 μM of wBK_a(F+R) primers, 3-5 μl of genomic DNA. Cycling conditions were 98°C for 30 s, followed by 35 cycles of 98°C for 10 s; 58°C for 20 s; 72°C for 2 min, and 72ºC for 6 min and a 4oC hold; 3) All 5.1 kb purified PCR were verified and confirmed by restriction enzymes XbaI, EcoRI, and direct sequencing.
Phân lập và khảo sát tình hình kháng kháng sinh của vi khuẩn Escherichia coli sinh độc tố shiga phân lập tại một bếp ăn tập thể ở khu vực Hà Nội
Authors: Le Thi Lan Anh , Vu Thi Thuong , Dinh Thu Minh , Bui Thi Thanh Nga , Ta Thi Loan , Pham Thi Ha Giang , Phamj Viet Hung , Trieu Phi Long
Published: May 2023

. coli contaminated food is increasingly common in Vietnam as well as in the world. In particular, the status of multi-drug resistant E. coli has been recognized and is of great concern globally. In this survey, we isolated 9 E. coli strains from food samples, surface of table samples and rectal swabs of kitchen staff at a collective kitchen in Hanoi city and examined the antibiotic resistant phenotype of 9 isolated E. coli strains on 24 common antibiotics. The results showed that only 1/9 strains were sensitive to 24 tested antibiotics, of which 8/9 strains were resistant to at least 2 antibiotics. 8/9 of strains were resistant to chloramphenicol and tetracycline, 7/9 strains were resistant to trimethoprim + sulfamethxazole, 5/9 strains were resistant to ampicillin, gentamycin, piperacillin, 4/9 isolates were resistant to cefuroxime, cefepime, cefotaxime and aztreonam. 3/9 strains resistant to cefazolin, tobramycin. 2/9 strains were resistant to ceftazidime and 1/9 isolates were resistant to amikacin and ciprofloxacin. 9/9 isolates were sensitive to amoxicillin/clavulanicacid, piperacillin/tazobactam, cefoxitin and carbapenem antibiotics such as ertapenem, imipenem and meropenem.
Nghiên cứu ảnh hưởng của hạt nano cobalt hoá trị 0 lên hàm lượng chlorophyll A và các thông số quang hợp của cây đậu tương Glycine max (L). Merrill “DT96”
Authors: Luu Thi Tam , Phan Thi Thu Hien , Vu Thi Loan , Dang Diem Hong
Published: May 2023

The application of nanotechnology in agriculture is a promising way to increase crop production and yield, reduce the amount of fertilizer, increase the storage time of the productions and protect the environmental sustainability. Soybean is one of the four important crops of Vietnam's agriculture and a source of food for humans and domestic animals. In this study, the effect of zerovalent cobalt nanoparticles with different concentrations (0; 0.17; 0.33 and 100 mg/kg seed) on chlorophyll a content and photosynthesis parameters of soybean plant Glycine max (L). Merr. DT96 which was planted in the autumn-winter crop in Xuan Hoa, Phuc Yen, Vinh Phuc were carried out. The obtained results showed that zerovalent cobalt nanoparticles had a positive effect on the photosynthetic parameters of soybean plants. At the used concentration of 0.33 mg cobalt/kg seed, the chlorophyll a content and photosynthetic parameters of soybean were the highest and there was a statistically significant difference compared with control. The chlorophyll a content tends to increase gradually and reaches the maximum value of 1.77 ± 0.05 mg/g fresh leaves after 40 days of sowing. The parameters related to chlorophyll fluorescence such as Fo (initial fluorescence), Fm (maximal fluorescence), Fv/Fm (maximal photochemical efficiency), effective quantum yield of photosystem II (FPSII), photosynthetic electron transport rate (ETR), Pn (net photosynthetic rate) of soybean seedlings which were treated by cobalt nanoparticles were higher than the control (except at the concentration of 100 mg/kg). The soybean seeds treated by cobalt nanoparticles had increased the chlorophyll a content of leaves and photosynthetic efficiency, leading to improve productivity of soybean.
Đặc điểm biến thiên nhịp tim của thủy thủ tàu ngầm
Authors: Bui Thi Huong , Nguyen Hong Quang , Hoang Van Huan
Published: May 2023

This study was aimed to evaluate the characteristics of heart rate variability as well as cardiovascular physiological indices on 278 submariners were divided into 3 groups: Group 1 consisted of 62 submariners aged 25 to 29 years old (mean 27.5 ± 0.1 years old); Group 2 consisted of 201 submariners, aged from 30 to 99 (mean 34.3 ± 0.1 years old); Group 3 consisted of 15 submariners, ages 40 to 48 (mean 41.7 ± 0.5 years). The characteristics of heart rate variability over time and frequency were measured and analyzed for 5 min using UPFT1/30 and Ritm-MET devices manufactured by companies Medicom MTD and INMET of the Russian Federation. The results of the study showed that: The average heart rate of the 3 groups was 69.9±0.9; 70.8±0.6 and 71.6±1.5 beats/min, respectively, the maximum blood pressure of the 3 groups is 114.6±1.1; 114.1±0.5 and 117.1±1.3mmHg, positively correlated with BMI (r=0.1, sig=0.03). Minimum blood pressure value is 71.4±0.7; 72.9±0.4 and 79.0±1.1mmHg, increasing with age (r= 0.3, sig < 0.01) and positively correlated with peripheral vascular resistance (r=0.7, sig < 0.01). Heart rate variability indices decreased and stress index increases with age. The average SDNN of the 3 groups is 0.061±0.002; 0.055±0.001 and 0.043±0.003s; 26.6% of submariners surveyed have SDNN less than 0.04s. Total power of groups decreased with age with a mean value is 3147±241; 2602±111 and 1626±246 with r=-0.2, sig<0.01. TP decreased due to HF, LF, and VLF all decreased, correlation coefficient r = 0.8. 46.4% (129 people) have optimal functional state and functional reserve with TP in the range 1500-4000ms2; 2.2% (6 people) infunctional state marked weakness, lack of functional reserve with TP < 300 ms2.
Đánh giá một số sinh phẩm và phương pháp tách chiết ADN vi khuẩn Mycobacteria trên mẫu bệnh phẩm thu thập từ bệnh nhân nhiễm lao
Authors: Pham Thi Ha Giang , Vu Thi Thuong , Bui Thi Thanh Nga , Pham Viet Hung , Pham Xuan The Anh , Le Thi Lan Anh
Published: May 2023

Tuberculosis is still burden in developing countries, including Viet Nam. Molecular techniques such as PCR, Real-time PCR play an important role in tuberculosis diagnostics. Specimens for tuberculosis testing are complex such as sputums, gastric fluids. DNA extraction are commonly performed by commercial kits, with little study about efficacy for tuberculosis testing assays. This study describes efficacy of three kits G-Spin (Intron-Korea), RIBO- sorb (Amplisens-Russia), DNA/RNA Prep (Sacace-Italy), and Salting-out method using basic reagents. Samples were 15 sputums collected from tuberculosis infected cases. As the result, recovered ADN was highest in DNA/RNA Prep, folowed by Salting-out, G-Spin, and last by RIBO - sorb. Oder of purification value was RIBO - sorb, G-Spin, Salting-out, and DNA/RNA Prep. About PCR for 16S gene, 15/15 samples were succeed in G-Spin and DNA/RNA Prep, 14/15 from RIBO-prep, 13/15 from Salting-out. Real-time PCR Mycobacterium tuberculosis (Sacace-Italy) detected 14/15 samples from G-Spin, DNA/RNA Prep, and RIBO-sorb, but Salting-out detected 13/15 samples. Therefore, G-Spin and DNA/RNA Prep show higher efficacy in amplication of 16S gene and Real-time PCR assays for tuberculosis. RIBO- sorb has equal efficacy in Realtime PCR, but more priority in purification. Salting-out perform equally in recovery and purification with commercial kits, but limited in efficacy of Mycobacteria genome amplification.
Chemical constituents from the arial of Crinum asiaticum L.
Authors: Pham Van Cong , Ngo Van Hieu , Ngo Viet Duc , Vu Thi Trang , Do Thi Thu Hien , Do Thanh Tuan , Nguyen Thi Thu Hien , Pham Ngoc Thuat , Nguyen Tuan Anh , Cu Lan Huong , Hoang Le Tuan Anh
Published: May 2023

Crinum asiaticum L. (locally known Nang hoa trang), belonging to the Crinum genus of the Amaryllidaceae family, has been widely used in oriental and traditional medicine around the world for the treatment of various diseases and exerts diverse promising pharmacological effects. To find out new inhibitors for the treatment of inflammatory and Alzheimer’s diseases, a methanol extract of the aerial part of C. asiaticum was investigated to afford six compounds, chrysophanol (1), emodin (2), physcion (3), thymine (4), thymidine (5), and 5-(hydroxymethyl)-2-furfural (6) by using various chromatographic separations. Their structures were identified by the extensive analysis of 1H- and 13C-NMR data as well as a comparison with those of previously reported data. This is the first report of these compounds (1-6) from C. asiaticum. In addition, all compounds evaluated the inhibitory activities of NO production and acetylcholinesterase (AChE). Among them, emodin (2) significantly inhibited NO production with an IC50 of 5.13±0.42 μM. This result indicated that emodin (2) may be beneficial in the treatment of anti-inflammatory diseases. Besides, all compounds (1-6) also showed weak inhibitory effects on the AChE enzyme with a range of IC50 values from 82.98±9.19 to 237.63±13.80 µM.
Nghiên cứu tổng hợp và khảo sát khả năng xử lý xanh methylen và đỏ Công gô trong môi trường nước của vật liệu composit từ tính oxit sắt/graphen oxit
Authors: Cao Phuong Anh , Han Duy Linh , Vu Minh Chau , Nguyen Thi Thu Hang
Published: May 2023

In this study, graphene oxide was prepared by the modified Hummers method, and then iron oxide nanoparticles were deposited on the surface of graphene oxide by hydrothermal method. After synthesis, these materials were characterized via a number of physical methods: X-ray diffraction, Fourier transform infrared spectroscopy (FTIR), vibrating sample magnetometer (VSM) and scanning electron microscopy (SEM/EDX). The results show that the iron oxide particles were synthesized with nano-size, and the material after modified by graphene oxide still retains the magnetism. These materials continue to be evaluated the for removing methylene blue and Congo red in the water. The results show that the synthesized composite materials can selectively adsorb methylene blue and Congo red, thereby showing the potential application of magnetic composite materials in the field of wastewater treatment.
Mô hình hấp phụ đẳng nhiệt và động học hấp phụ phosphat trên vật liệu hydrotalcit Mg-Al/CO3
Authors: Nguyen Thi Thu Hang , Le Bao Hung , Nguyen Kim Thuy , Cao Phuong Anh , Vu Minh Chau
Published: May 2023

In this paper, the hydrotalcite Mg-Al/CO3 material was synthesized successfully with an Mg/Al molar ratio of 2:1 by the co-precipitation method. SEM images, XRD patterns and FTIR Spectra and Energy Dispersive X-ray Spectra (EDX) of the material were analyzed. Equilibrium adsorption isotherms and kinetic models of the phosphate adsorption process on the hydrotalcite material Mg-Al/CO3 were investigated. The experimental data were analyzed by Langmuir and Freundlich models of adsorption. The phosphate adsorption on the material was well fitted to both Langmuir and Freundlich isotherms, and the maximum adsorption capacity was found to be 46.95 mg/g with the material sample was calcined at 600oC. The kinetic data obtained at different concentrations have been analyzed using a pseudo-first-order and a pseudo-second-order equation. The experimental data fitted very well with the pseudo-second-order kinetic model.
Dự báo tốc độ ăn mòn kẽm trong khí quyển trên cơ sở ứng dụng mạng nơ-ron nhân tạo
Authors: Nguyen Manh Thao , Pham Van Nguyen
Published: May 2023

The article presents the prediction of zinc corrosion rate in the atmosphere by applying an artificial neural network (ANN). The results indicate that the forecast has high accuracy with the correlation coefficients of 97-98%. This is a good orientation of applying an artificial neural network to predict the metal corrosion rate in Vietnam.
DAMPAK GEMPA BUMI LOMBOK TAHUN 2018
Authors: Supartoyo  , Robiana Rahayu , Natalia Merry Christina , Hespiantoro Suryo
Published: May 2023

Serangkaian kejadian gempa bumi di Pulau Lombok dan sekitarnya pada 29 Juli 2018, 5 Agustus 2018, dan 19 Agustus 2018 mengakibatkan korban jiwa sebanyak 559 orang, 1.478 orang luka-luka, dan 185.483 bangunan mengalami kerusakan. Semua jenis bahaya gempa bumi, yaitu efek guncangan, sesar gempa bumi minor (minor fault surface rupture), dan bahaya ikutan berupa retakan tanah, likuefaksi, dan gerakan tanah muncul akibat gempa bumi tersebut. Guncangan gempa bumi terasa kuat di Lombok Utara dan Lombok Timur mencapai skala intensitas gempa bumi VIII MMI (Modified Mercally Intensity). Kejadian gempa bumi 29 Juli 2018 dengan M 6,4 mengakibatkan terbentuknya rupture zone: 218,7762 km2 . Adapun kejadian gempa bumi 5 dan 19Agustus 2018 dengan M 7,0 menghasilkan rupture zone: 758,5776 km 2.
PERANAN LITOLOGI TERHADAP EROSI PADA DAS CIMANUK BAGIAN HULU
Authors: Raja Denny Lumban , Sukiyah Emi , Sulaksana Nana , Endyana Cipta
Published: May 2023

Bagian hulu pada daerah aliran sungai (DAS) sangat memengaruhi daerah hilir. Salah satunya, yaitu proses erosi pada hulu dan proses sedimentasi pada hilirnya. Hal ini harus diperhatikan karena sedimentasi berlebih pada hilir dapat berpotensi banjir. Batuan daerah penelitian yang didominasi oleh batuan vulkanik memiliki tingkat ketahanan terhadap erosi yang beragam, yaitu dari lava yang sangat tahan terhadap erosi hingga material lepasan vulkanik yang sangat rentan. Penelitian dilakukan dengan analisis studio, analisis laboratorium, sertauji normalisasi dan korelasi. Hasil dari penelitian didapatkan bahwa daerah aliran Sungai Cimanukmemiliki nilai erosi dan sedimentasi yang beragam karenadaerah tersebutmempunyai litologi yang beragam dari hasil vulkanisme. Akan tetapi, nilai erosi dan nilai sedimentasinya ternyata saling berbanding lurus dan sangat berkorelasi. Hal ini membuktikan bahwa memang erosi pada bagian hulu sangat memengaruhi sedimentasi di bagian hilir pada Daerah Aliran Sungai Cimanuk.
KARAKTERISTIK MORFOMETRI DAS CITARIK HULU DAN IMPLIKASINYA TERHADAP POTENSI BANJIR
Authors: Rendra Pradnya Paramarta Raditya , Sulaksana Nana
Published: May 2023

Daerah penelitian merupakan Sub-DAS Citarik Hulu yang terletak pada 107°49’18,1” BT- 107°57’27,4” BT dan 6°55’15.7” LS-6°59’34.7” LS di wilayah Kabupaten Bandung, Sumedang, dan Garut. Penelitian bertujuan mengidentifikasi karakteristik morfometri Sub-DAS Citarik Hulu serta implikasinya terhadap potensi banjir. Penelitian dilakukan melalui analisis studio dengan memanfaatkan peta tematik, seperti peta kemiringan lereng dan peta geologi. Beberapa aspek morfometri daerah aliran sungai (DAS) digunakan untuk menentukan karakteristik Sub-DAS Citarik Hulu, yaitu aspek linear (orde sungai, panjang sungai orde “u”, rata-rata panjang sungai, rasio panjang sungai, rasio cabang sungai, dan rata-rata rasio cabang sungai); aspek areal (kerapatan drainase, tekstur drainase, faktor bentuk, rasio sirkularitas, rasio elongasi, dan panjang aliran permukaan); serta aspek relief (relief DAS dan rasio relief). Hasil penelitian menunjukkan DAS Citarik Hulu terdiri dari 17 Sub-DAS. Secara umum, seluruh Sub-DAS tersebut memiliki bentuk memanjang yang berada pada relief tinggi dan kemiringan relatif curam, litologi penyusun batuan vulkanik, serta kenaikan muka banjir yang lambat. Hal tersebut mengindikasikan bahwa daerah penelitian memiliki ketahanan yang relatif tinggi terhadap potensi banjir. Sebagai salah satu area resapan DAS Citarum di bagian hulu, sudah sepatutnya kondisi DAS Citarik Hulu tetap dijaga agar terhindar dari berbagai kerusakan alam. Oleh karena itu, kondisi Sub-DAS Citarik Hulu perlu keberlanjutan konservasi agar tidak terjadi kerusakan lingkungan yang mengakibatkan terjadinya berbagai bencana, seperti banjir dan longsor.
Hubungan Keterampilan Membaca Pemahaman dan Keterampilan Menulis Teks Cerpen Siswa Kelas IX SMPN 2 Bukik Barisan Payakumbuh
Authors: Dona Intan Rahma , R Syahrul
Published: May 2023

This study has three objectives: (1) to describe the level of reading comprehension skills of class IX students of SMPN 2 Bukik Barisan Payakumbuh, (2) to describe the level of short story writing skills of class IX students of SMPN 2 Bukik Barisan Payakumbuh, and (3) to describe the relationship between reading skills understanding and skills in writing short stories for class IX students of SMPN 2 Bukik Barisan Payakumbuh. This type of research is quantitative research with descriptive methods. Based on data analysis, reading comprehension skills greatly influence the short story writing skills of class IX students of SMPN 2 Bukik Barisan.
Perkembangan (Kognitif, Fisik-Motorik, Sosio-Emosional) dan Penanaman Nilai Agama pada Masa Pranatal
Authors: Sipayung Ami Syadila
Published: May 2023

This study aims to find out how cognitive, physical-motor, socio-emotional development is in the prenatal period and to find out how religious values are instilled in the prenatal period. The method used in this research is qualitative research with a library research approach, namely research whose subject is in the form of library literature. Sources of data depart from documentation from books and scientific journals that discuss development (cognitive, physical-motor, socio-emotional) and the inculcation of religious values in the prenatal period. The results of this study indicate that it is very important for parents to maintain development in the prenatal period. Attention from both parents, mother and father is needed in the prenatal period so that the growth and development of the baby in the womb is healthy and does not lack anything. prenatal development from a cognitive perspective, such as when a baby sucks a finger in the womb. From a physical point of view, physically it seems that every month the baby experiences development and growth. In terms of social emotions without many realizing it, mother and fetus already have a very strong emotional connection. It is also important for parents to instill religious values in the prenatal period, the methods that can be used by parents in instilling religious values in the prenatal period are: Story telling (communication) method, prayer method, dhikr method, dialogue method, and worship method.
Upaya Meningkatkan Hasil Belajar Bahasa Indonesia melalui Penggunaan Media Gambar Siswa Kelas VIII.H SMP Negeri 12 Mataram
Authors: Mukasri Mukasri
Published: May 2023

This study aims: to find out the use of media images in learning Indonesian in class VIII.H students at SMP Negeri 12 Mataram Odd Semester in the Academic Year 2021/2022. And to find out the increase in Indonesian learning outcomes through the use of media pictures of class VIII.H students of SMP Negeri 12 Mataram Odd Semester 2021/2022 Academic Year. This research was designed using Classroom Action Research. The subjects in this study were class VIII.H students of SMP Negeri 12 Mataram, totaling 31 people, consisting of 15 female students and 16 male students. While the research procedure goes through the stages of Planning, Action Implementation, Observation, and reflection. The results showed that the results of learning Indonesian for class VIII.H students of SMP Negeri 12 Mataram in the 2021/2022 academic year, using media images could be improved with the final result of the study being the class average before the action of 69.06 or classical completeness of 61.29 %, to 73.68 or 74.19% classical completeness in cycle I, increased to an average of 74.84 or 77.55% in cycle II and increased to an average test of 80.45 or 100% in cycle III. From the results of student observations it was shown that there was an increase in student activity in cycle I obtained a score of 17 or 60.70% to 20 or 71.43% in cycle II and 24 or 85.17 in cycle III. The increase in student activity in learning Indonesian was supported by the increase in teacher activity in maintaining and improving the learning atmosphere using media images, this can be seen from the observations of teacher activities where in cycle I a score of 22 or 61.10% was obtained, becoming 26 or 72, 23% in cycle II and increased to 33 or 86.12% in cycle III.
Penerapan Model Pembelajaran Saintifik untuk Meningkatkan Motivasi dan Hasil Belajar Matematika Siswa Kelas VIII.C SMP Negeri 12 Mataram
Authors: Istiroha Istiroha
Published: May 2023

The purpose of this study was to find out: 1) How did the motivation to learn Mathematics increase after applying the scientific learning model to class VIII.C students of SMP Negeri 12 Mataram even semester of the 2021/2022 Academic Year; 2) How did the learning outcomes of Mathematics increase after the scientific learning model was applied to class VIII.C students of SMP Negeri 12 Mataram even semester of the 2021/2022 Academic Year. The research subjects totaled 32 students consisting of 17 male students and 15 female students. The subjects that were the target of the research were Mathematics. Based on the results of the achievement of action research indicators in class VIII.C of SMP Negeri 12 Mataram which were carried out in three cycles, it can be concluded that the learning outcomes of class VIII.C students of SMP Negeri 12 Mataram for the academic year 2021/2022, with a scientific learning model can be improved with the final results research is the class average before the action 67.94 or 53.13% classical completeness, to 72.63 or 65.63% classical completeness in cycle I, increased to an average of 74.69 or 81.25% in cycle II and experienced an increase to an average test of 76.94 or 90.63% in cycle III. From the results of student observations it was shown that there was an increase in student motivation which in cycle I obtained a score of 2.93 or Less to 3.33 or Enough in cycle II and 3.92 or Good in cycle III. The increase in student activity in learning mathematics is supported by the increase in teacher activity in maintaining and improving the learning atmosphere using the scientific learning model, this can be seen from the observations of teacher activities where in cycle I a score of 22 or 61.10% was obtained, becoming 26 or 72, 23% in cycle II and increased to 33 or 86.12% in cycle III.
Penggunaan Permainan Kartu Bergambar untuk Meningkatkan Kemampuan Membaca Permulaan Anak Usia 5-6 Tahun di TK PGRI 2 Mataram
Authors: Suarni Ni Luh
Published: May 2023

This study aims to find out how much picture card games can improve the early reading skills of children aged 5-6 years in PGRI 2 Mataram Kindergarten in the 2021/2022 academic year. This research is a classroom action research. The subjects in this study were 19 students of TK PGRI 2 Mataram with 8 male students and 11 female students. Based on the results of the research and discussion, it can be concluded that early reading skills in children aged 5-6 years at TK PGRI 2 Mataram can be improved using picture word cards as media. This can be proven from the results of increasing the ability to read early. In the initial conditions the average achievement was 66.67% and an increase of 11.11% so that in Cycle I it reached 77.78% and in Cycle I to Cycle II it increased by 18.71% so that in Cycle II it reached a score of 96 ,49%.
Implementasi Peraturan Walikota Padang Nomor 38 Tahun 2021 tentang Pengelolaan Kampung Nelayan
Authors: Ramayanto Aldo , Kusdarini Kusdarini , Kabullah Muhammad Ichsan
Published: May 2023

This research is motivated by the existence of the Padang City Government policy on the management of fishing villages, which aims to optimize the arrangement of fishing villages, improve the fishermen's welfare, increase the effectiveness and efficiency of fishing village areas, and realize coordination, integrity, synchronization, and consistency between related parties in the management of fishing villages. If you look at the condition of fishermen in Padang City, especially in Pasie Nan Tigo Village, it is a step to carry out this policy so that the fishing community in this village can improve their welfare with the existence of this fishing village. The research was conducted using a descriptive type of qualitative method. Data was gathered through interviews with the chosen informants through a purposive sampling technique, supplemented by observation and documentation studies, and analyzed using Miles and Huberman's data analysis techniques. This study uses the theory of implementation according to Donald S. Van Meter and Carl E. Van Horn, which consists of six variables, namely policy standards and objectives, resources, inter-organizational communication and strengthening of implementing activities, characteristics of implementing agents, disposition of implementors, and the economic, social, and political environment. The results of this study show that the implementation of the Padang Mayor Regulation Number 38 of 2021 concerning the Management of Fishermen's Villages has been running but is not optimal yet. This can be seen in the budgetary resources that were been constrained during the COVID-19 pandemic and the inflation in the city of Padang. As well as the influence of the social, economic, and political environment on the implementation of policies. Therefore, the Padang City Fisheries and Food Service, as the leading sector, needs to maximize all resources and improve coordination and communication so that this policy can run optimally.
Mapping the Tourism Village Potential at Triangle of Diamond Banyuwangi
Authors: Febrian Ayu Wanda , Sandi Dora Melati Nurita , Amalia Firda Rachma , Perdana Muhamad Ari
Published: May 2023

Banyuwangi Regency refers to the tourism industry as its leading source of regional income, promoting its tourism destination icon: The Triangle of Diamond. In addition to being an icon, The District Medium-Term Development Plan of Banyuwangi 2016-2021 asserted the Triangle of Diamond as its major project in the Tourism Development Area (TDA). Mount Ijen Crater in Licin District is assigned as TDA I, Plengkung Beach in Tegaldlimo District is designated as TDA II, and Sukamade Beach in Pesanggaran Subdistrict is registered as TDA III. It is expected that tourism is well-developed in rural areas and may increase the prosperity of its people. The analysis of the interactive model of Miles and Huberman (1992), we collected data, gave and recapitulated scores, and determined the final category as a tourist village. The results showed that Kemiren Village in area I, Kalipait Village in area II, and Sumberagung Village in area III are categorized as tourism villages. The three villages have corresponding advantages in cultural aspects, which can then be used to determine a tourism village development strategy. The area I involved the villages of Kemiren, Tamansari, and Kampunganyar. Area II involved Kedungasri, Kalipait, and Purwoagung villages. Area III involved the villages of Sarongan, Sumberagung, and Kedungwungu. Kemiren, Kalipait, and Sumberagung villages have the same advantages in cultural aspects, which can then be used to determine a tourism village development strategy.
Value Chain Analysis in Retail Shop Case Study: “Dizzle Otx Game Shop”
Authors: Rivaldy M. Labib , Dian Sua Pratama Bayu
Published: May 2023

Value chains are often used to assess and find suitable techniques to increase competitive advantage. This research uses Value Chain with the aim of analyzing the retail store industry. Retailer becomes the end of distribution activities from producers to End Customers. The object of research used is Game Store and Hobby, this retailer is in the city of Surabaya, Indonesia. Method using descriptive analytic method using primary data from observations and interviews with business owners. From the analysis conducted aims to create one stop shopping that can increase competitive advantage by increasing product variations and staying up to date with market interest in game discs and game consoles as well as various equipment related to the game world both merchandise and accessories. That way customers can easily find the desired product easily in one store. This will increase the interest of a community in the area to do one stop shopping at this store. Increase distributor network to get cheaper prices and improve store appearance, use of technology, and customer service.
Proyecto Salactiva. Diseño e Implementación de Espacios de Aprendizaje. Una experiencia de Innovación
Authors: González Hermosilla Alejandra
Published: May 2023

El presente capítulo sintetiza la realización del proyecto Salactiva, que fue realizado en la Región de la Araucanía el año 2016 en Chile. El objetivo fue crear una Sala de Estimulación Sensorial en Escuela Especial de la Comuna, para potenciar la formación de individuos conscientes, desafiándolos a promover cambios que disminuyan las brechas y que abran las oportunidades. Esta iniciativa surge de la necesidad de crear nuevas estrategias metodológicas para apoyar la enseñanza en la educación especial a través de la Teoría de Integración Sensorial, con la modificación conceptual de la Estimulación Sensorial y la Educación de las Emociones. Para llevar a cabo este proceso se llevó a cabo un acercamiento y estudio de la realidad de las escuelas especiales en Chile, de la nueva ley de inclusión, modificación del decreto 87/90 y el decreto 815/90, posteriormente la creación de una sala modelo, la capacitación y finalmente la supervisión y evaluación del proyecto.
Aplicaciones tecnológicas en contextos educativos interculturales: experiencia de trabajo interdisciplinario
Authors: Uribe Sepúlveda Pilar Andrea , Zúñiga Gómez Patricia Andrea
Published: May 2023

La propuesta que presentamos a continuación tiene como objetivo socializar el diseño, creación y elaboración de una aplicación tecnológica para trabajar el desarrollo de habilidades lingüísticas en niños menores de 6 años, procedentes de contextos educativos interculturales indígenas. Este trabajo comenzó a desarrollarse en el año 2015, como una iniciativa de trabajo interdisciplinario entre profesionales y estudiantes de pregrado de las carreras de educación parvularia (educación infantil) y diseño gráfico. Nuestro eje movilizador en la constitución de este grupo de trabajo es construir artefactos educativos tecnológicos, que contengan imágenes polisémicas capaces de representar el entorno cultural y social de los párvulos (Lotman, 2004) pues uno de los nudos críticos que hoy enfrentan las prácticas pedagógicas en escenarios interculturales, es la escasez de materiales concretos que faciliten los procesos de enseñanza y aprendizaje.
Las emociones morales en la intervención educativa
Authors: Robles Francia Víctor Hugo
Published: May 2023

Los antecedentes sobre intervenciones educativas en el juicio moral son limitados. El juicio moral es la capacidad de tomar decisiones y resoluciones morales, esto como una competencia valorativa moral basada en principios internos donde los individuos actúan conforme a ella. Los niveles de juicio moral de estudiantes y profesores reflejan un nivel limitado de reflexión moral en el entorno mexicano. Se pensaba que el Método de Discusión de Dilemas sería un método adecuado al entorno educativo mexicano, sin embargo, varios resultados de su aplicación en estudiantes y trabajadores muestran nulas o negativas afectaciones reflexivas morales. Estas complicaciones, sobre el razonamiento moral y su crecimiento a partir de intervenciones educativas, solicitan imperativamente una comprensión sobre la estructura cognitiva. Pero sobre todo, entender la afectación de las emociones en la maduración moral de la vida humana, pues se relacionan con la cognición del pensamiento moral de los individuos. Se pretende construir un referente para diseñar tareas morales emotivas relevantes, ítems, dilemas y casos, relacionados con el razonamiento moral del sujeto y de los individuos en la organización. Esto, a través del estudio de las reacciones emotivas, sobre el orgullo y la vergüenza de los sujetos, logrando una mayor comprensión de su juicio moral. La triada formada por el agente moral, el observador y las consecuencias de la acción, entre quien actúa, el espectador y la respuesta de las consecuencias, es aplicada a los seis estadios en los tres niveles morales de justicia recíproca.
Aprendizaje-Servicio, una práctica pedagógica que promueve el enganche de los menores
Authors: Mayor Paredes Domingo
Published: May 2023

Este trabajo presenta los resultados parciales de un estudio enfocado hacia el análisis de la influencia que tienen los proyectos de Aprendizaje-Servicio para favorecer la participación fuerte de los menores en la construcción de su entorno. La investigación tomó como eje de estudio un proyecto que se implementaba en un centro educativo de primaria, ubicado en un contexto socialmente desfavorecido, donde participaron profesorado y alumnado de primaria, estudiantado universitario y diversos agentes socio-educativos. Para ello se utilizó el estudio de caso como metodología de la investigación y la observación participante, análisis de documentos, cuestionario de preguntas abiertas y entrevistas en profundidad como instrumentos para la recogida de información. Los resultados obtenidos permiten constatar que las acciones de Aprendizaje-Servicio, a diferencia de las prácticas tradicionales donde al alumnado se le asigna un rol más pasivo, promueven la participación compartida, favoreciendo un rol protagónico, tanto del alumnado como del profesorado. A partir de los resultados alcanzados se concluye que el Aprendizaje-Servicio se puede contemplar como una práctica educativa innovadora que posibilita la incorporación de la voz del alumnado como un elemento de mejora de la educación escolar y social. Todo ello se somete a discusión y se señalan nuevas perspectivas de investigación.
Influencia de los estados emocionales contrapuestos en el rendimiento académico infantil
Authors: Pulido Acosta Federico
Published: May 2023

Este trabajo tiene como objetivo analizar los niveles de Ansiedad, Felicidad y Rendimiento Académico (RA), en función de la edad, género, cultura y estrato socioeconómico, así como contemplar las relaciones que se pudieran dar entre las variables, para una población infantil multicultural. Para ello, se ha contado con 764 participantes, de siete centros en los que se imparte formación perteneciente a la Etapa Primaria. Considerando la cultura, el grupo mayoritario es el de participantes pertenecientes a la cultura-religión musulmana. Estos constituyen el 74.2% de la muestra, mientras que el 25.8% de la misma pertenecía a la cultura-religión cristiana, siendo el 53.2% varones y el resto de la muestra (46.8%) mujeres. Como instrumentos de evaluación se han empleado el STAIC (Spielberger, 2001), un cuestionario para evaluar la Felicidad y las calificaciones de los alumnos. Las variables edad, género, cultura/religión y estatus influyen en Ansiedad y Felicidad. Se halló relación inversamente proporcional entre Ansiedad y Felicidad. En Rendimiento influyen edad, género, cultura/religión y estatus, encontrándose relación inversa entre Ansiedad y RA. Felicidad y RA son directamente proporcionales.
THE EFFECT OF THE COVID-19 PANDEMIC ON SUICIDE ATTEMPTS OF INDIVIDUALS AGED 65 AND OVER
Authors: ŞENER Aslı , MERAL Orhan
Published: May 2023

Objective: The aim of this study is to examine whether the Covid-19 pandemic affects the suicide attempts of elderly individuals aged 65 and over and to offer solutions for the prevention of these suicide attempts.

Methods: The medical records of elderly patients aged 65 years and over who applied to the Emergency Department between March 01, 2016, and March 31, 2022, were retrospectively analyzed. "Pre-pandemic period" suicide attempts and "Pandemic period" suicide attempts were handled separately. Age, gender, length of hospital stays, type of suicide attempt, psychological status, post-examination status, whether he lived alone or with his family, whether there was a recurrent suicide attempt and whether there was a history of psychiatric illness were recorded in the case study forms. SPSS (version 26.0) package program was used for statistical analysis. Demographic data were expressed as numbers and percentages.

Results: In this study, the records of 71 patients over the age of 65 were reviewed retrospectively. It was determined that the total number of patients who attempted suicide during the pandemic period showed a statistically significant increase compared to the pre-pandemic period (p<0.00001), and there was a 3.56-fold increase in suicide attempts over 65 years of age.

Conclusion: Comorbidities with old age negatively affect the quality of life and lead people to despair. Isolation measures taken in old age, when the need for social support increases, pushes the elderly to loneliness even more, and this situation emerges as increasing suicide attempts.
Effects of postoperative three-balls respiratory exercise on respiratory function tests in smoking patients who underwent extremity surgery under generel anesthesia.
Authors: ŞENVELİ Muzaffer , ÇOLAK Alkin , YILMAZ Makbule Elif , HEKİMOGLU SAHİN Sevtap , TURAN Fatma Nesrin
Published: May 2023

Aim:Incentive spirometry is used to reduce pulmonary complications after surgical interventions under general anesthesia. In this study, we aimed to investigate the effect of postoperative incentive spirometry on pulmonary function tests in patients who smoke and undergo extremity surgery under general anesthesia.
Study design: Eighty patients with ASA I-II physiological score, aged 18-61 years, who underwent extremity operation in a 3rd level hospital were included in the study. After the patients were divided into two groups as 40 patients in each group, smokers of 10-20 cigarettes per day for at least 5 years and non-smokers and the groups were once more randomized according to whether they would use incentive spirometry (three balls of breathing exercise) or not. Group K (n=20):Non-smoker and not using incentivespirometry, Group T (n=20): Non-smoker and using incentivespirometry, Group S (n=20): Smoker of 10-20 cigarettes per day for at least 5 years andnot using incentive spirometry, Group ST (n=20): Smokers of 10-20 cigarettes per day for at least 5 years and using incentive spirometry.
Results:The demographic data similar between the groups. When the groups were compared in terms of preoperative and postoperative FVC and FEV1 values, the postoperative FVC values in Group K and Group S were found to be significantly lower than the preoperative values (p=0.001, p=0.002, respectively). Postoperative PEF values were significantly lower than preoperative values (p=0.024, p=0.024, p=0.001, respectively). When compared within groups, postoperative VC values in Group K and Group S were found to be significantly lower than preoperative values (p=0.037, p=0.012, respectively). When the groups were compared statistically in terms of preoperative and postoperative FEV1/FVC values, no significant difference was found (p>0.05).
Conclusion:It was found that postoperative worsening of respiratory function test values in smokers who received general anesthesia has improved with the use of incentive spirometry. For this reason, it is assumed that the use of incentivespirometry in the postoperative period in extremity operations performed under general anesthesia will be helpful in preventing postoperative respiratory complications.
A BIBLIOMETRIC STUDY ON “BRAIN ABSCESS” IN WEB OF SCIENCE DATABASE
Authors: ÇAVUŞOĞLU Emre , MERAL Orhan
Published: May 2023

Purpose The aim of this study is to analyze the articles in the ISI Web of Knowledge-Science database with the keyword "brain abscess" in the title and to make a bibliometric analysis.
Study plan As a result of the research made in the WoS database; The years in which the articles were published, the journals in which they were published and the languages of publication, the publisher companies of the journals, the countries where the studies were conducted, the first name authors of the articles and the institutions the authors were affiliated with, the categories of the studies in the WoS database and whether financial support was received in the preparation/publishing of the studies were examined, the number of citations to the articles was single were calculated individually and collectively.
Results Within the scope of the study, 994 articles containing the keyword "Brain Abscess" were identified. It was determined that a total of 16330 references were made to these works and the H index was 57. Among the countries where the articles were published most frequently (n=41, 4.1%) in 2008, most frequently (n=29, 3.0%) were published in the journal Surgical Neurology, and the majority (n=892, 89.8%) were published using English language. It was determined that America (n=239, 24.0%) came first.
Conclusion The presented study is the first to demonstrate Turkey's research efficiency in this area. Thanks to the increase in bibliometric research, we suggest that the scientific efficiency values of the published studies will be revealed and that future studies should be reviewed accordingly, and new bibliometric researches should be conducted.
Globalization: Perspectives from Cultural Relativism and Modernism
Authors: Qazi Faryal
Published: May 2023

Globalization has created major changes in how the world works and conducts its business, but it has also generated a debate upon the viability of cultural practices around the world as the world becomes more connected, and there’s debate on if these differences strengthen the bond among the people of world or are they another chink in the armor. This paper attempts to explain the two dominant perspectives on changing cultural diversity, universalism and relativism to explain the challenges and opportunities globalization faces because of cultural diversity and unity, and tries to ascertain which approach would work best for the everchanging world of the future. Theories of relativism and modernism are applied, and the perspective of globalization is judged through the approaches of universalism and relativism to ultimately arrive at the conclusion that universalism is the way forward for globalization to progress.
Public opinion on the Palestinian question is more decisive than ever
Authors: Vizcarra Arantza
Published: May 2023

The Palestinian question is long-lasting. While Israel’s constant violations of international law exacerbate the Palestinians’ emergency call, public opinion has remained strong. This paper aims to assess the impact of civil society on the conflict-resolution. Existing research on the subject has usually focused on the reasons for the conflict or the importance of international initiatives. This report is based on an interpretative methodology that compares quantitative evidence on public opinion in Palestine and Israel, as well as qualitative information on observations, perceptions, and viewpoints in conflict resolution. The author argues that Palestinian public opinion can be both support or an obstacle in the conflict. This study allows obtaining information for a more balanced and, ultimately, more relevant approach to assessing public opinion and responding accordingly.
71 Years of Pak-China Research & Development Cooperation: Regional Dynamics and the Way Forward
Authors: Mumtaz Tahir , Noor-ul-Ain
Published: May 2023

Pak-China friendship is one of its kind in the global world that started 75 years ago and is still rising and shining with complete dedication. This research paper deals with the mutual research and developmental projects of China and Pakistan. One of the major projects is the CEPC and many other technological projects for advancement in all the fields of life for both countries. Many countries in the world have reservations regarding this unbreakable bond of friendship between Pakistan and China. For this reason, Pakistan and China face a lot of difficulties while on their way to progress. This paper highlights some of those major problems and provides tentative solutions for solving these issues at the governmental level.
Will China invade Taiwan: War Game Strategy and Lessons for China from the Russia-Ukraine Conflict
Authors: Obaid-Ur-Rehman
Published: May 2023

The China-Taiwan crisis is witnessing a paradigm shift amid rising uncertainty due to the Russia-Ukraine conflict. Every act, smaller or larger in western capitals against Russia in the context of the Russia-Ukraine conflict, is enlightening the Chinese policymakers, strategists, and leadership calculations over their futuristic war choices and possible invasion of Taiwan. There is a high chance of China invading Taiwan. What will be the future of Taiwan, the center for new American security has war gamed the situation and has revealed a possible conflict between China and Taiwan, dragging America to the center of the conflict. The game strategy has been used as a conceptual framework, to shed light on what planning, policymaking, and strategies will be required to deal with the hypothetical scenario. How will China react in the future, if Taiwan tries to become even closer to the western world, particularly America? The military blunders of the Russian army on the battlefield, the western united front against Russia on economic sanctions, the powerful strategy of information warfare in the digital world by the Zelensky government, and the response of the international community to Moscow’s invasion have sent shockwaves across China’s policy-making circles, but so far it hasn’t deterred the leadership morale in shaping its narrative of reunification. This study helps to analyze, the war gaming perspective of the China-Taiwan possible conflict, apart from war gaming scenarios, it also analyzes the actual situation, on how China would deal with the situation on economic, information, and diplomatic fronts. It also helps us to understand, why the conflict will be of tremendous importance, especially to America’s pacific and western allies.