bluuebunny/crossref_metadata_2025 huggingface dataset:
Una década de luchas contra los desahucios. De la vergüenza y la soledad a los agenciamientos cotidianos
Authors: Álvarez Veinguer Aurora , Sebastiani Luca
Published: March 2019

Este artículo se inscribe en una etnografía colaborativa junto con el colectivo Stop Desahucios Granada-15M, originado en el movimiento de los/as indignados/as 15M, que lucha por el derecho a la vivienda y contra los desahucios. Al recorrer el proceso afrontado por las personas que acuden al grupo y retomar sus propios relatos, ilustramos cómo los sentimientos experimentados al comienzo de soledad, vergüenza y fracaso individual se van transformando, mediante las prácticas desplegadas de cuidados y lucha, en agenciamientos colectivos y generan una política de los vínculos que trasciende la dependencia del Estado-mercado y la dicotomía público-privado. Formulamos ejemplos de estas prácticas entendiéndolas como una forma de hacer frente a la vulnerabilidad estructural que atraviesa las vivencias de las personas afectadas y conceptualizándolas como agenciamientos cotidianos —destacando la dimensión colectiva de producción de enunciados, deseos y formas de subjetivación—. Concluimos discutiendo la capacidad de resignificar políticamente el sufrimiento desplegada por el grupo y definiéndola como un proceso de subjetivación política.
The uses and abuses of "vulnerability" in EU asylum and refugee protection: Protecting women or reducing autonomy?
Authors: Freedman Jane
Published: March 2019

El concepto de vulnerabilidad se ha convertido en el centro de la legislación y la política europeas de asilo y refugio en los últimos años. La adopción de medidas especiales diseñadas para ofrecer una mayor protección a los solicitantes de asilo vulnerables puede considerarse un paso positivo. Ahora bien, la forma en que se ha definido la vulnerabilidad es cuestionable. Con demasiada frecuencia, la vulnerabilidad se reduce a una categorización simplista y esencializada, que también es altamente generizada y racializada. Las mujeres son clasificadas como "vulnerables" a priori, sin una consideración real de las causas estructurales y contextuales de esta vulnerabilidad. Si bien ser clasificado como "vulnerable" puede aumentar las posibilidades de protección dentro de los sistemas de asilo y refugio de la UE, los impactos en quienes son clasificados como vulnerables pueden ser sentidos como formas de violencia simbólica que reducen la agencia y la autonomía. En base a entrevistas con solicitantes de asilo y refugiados, así como en un análisis de las recientes directivas de asilo de la UE, este artículo propone repensar los usos de la vulnerabilidad en las políticas de asilo de la UE para proporcionar una mejor protección al tiempo que reconozcan la agencia y la autonomía de los solicitantes de asilo y de los refugiados.
MERKEZ BANKASI POLİTİKA FAİZ ORANI VE DÖVİZ KURU İLİŞKİSİ: TÜRKİYE ÖRNEĞİ
Authors: BAĞCI Erdem
Published: March 2019

Merkez
bankaları döviz kuru dalgalanmalarını azaltmak için faiz politikası aracını sık
kullanmaktadırlar. literatürde, faiz oranlarının döviz kurunu etkileyip
etkilemediği tartışılmaktadır. Bu çalışmada merkez bankası politika faiz oranı,
ABD doları döviz kuru ve EURO döviz kuru ilişkisi incelenmiştir. Türkiye’de
2003 – 2018 dönemini kapsayan verilerle, Merkez bankası politika faizi, ABD
dolar kuru ve Euro kuru ilişkisi ekonometrik yöntemlerle analiz edilmiştir.
Sahte korelasyonu önlemek ve değişkenlerin aynı düzeyde durağan olup olmadığını
anlamak için Augmented Dickey Fuller (ADF) birim kök testi yapılmıştır.
Değişkenler arasındaki nedensellik ilişkisini belirlemek için VAR analizi ve
Granger nedensellik testi uygulanmıştır. Elde edilen sonuçlara göre, politika
faiz oranı ile döviz kuru arasında çift yönlü anlamlı bir ilişki olduğu tespit
edilmiştir. Bu bağlamda, Türkiye’de döviz kurunda yaşanan dalgalanmaları
azaltmak için politika faizinin etkin bir araç olduğuna yönelik bulgulara
ulaşılmıştır.
TÜRKÇE ÖĞRETMENLERİNİN METİN İŞLEME SÜRECİNDE KULLANDIKLARI GERİBİLDİRİM TÜRLERİNE YÖNELİK BİR ARAŞTIRMA
Authors: GÖÇER Ali , ŞENTÜRK Rahime
Published: March 2019

Bu
araştırmanın amacı, Türkçe öğretmenlerinin ders
işleyiş sürecinde kullandıkları geribildirim türlerini ortaya koyarak süreçte
verilebilecek geribildirim türleri ile ilgili farkındalık oluşturmaktır. Çalışmada nitel
araştırma yaklaşımı çerçevesinde görüşme, gözlem ve doküman inceleme yöntemleri
kullanılmıştır. Araştırma, Kayseri ve Samsun illerinde görevli Türkçe
öğretmeninden oluşturulan 28 kişilik bir çalışma grubu üzerinden yürütülmüştür.
Çalışma grubu, amaçlı ve kümeleme örnekleme yöntemleri tercih edilerek
oluşturulmuştur. Araştırmada
incelenen veriler iki sorulu yarı yapılandırılmış görüşme formu ile elde
edilmiş ve betimsel analizi yapılmıştır. Gözlem formu ile elde edilen veriler
ise içerik analizi tekniğiyle öğretmenin öğrenci soru ve cevaplarına verdiği
geribildirimler, etkinliklerle ilgili olarak konu anlatımı sürecinde ve dersin
sonunda verdiği geribildirimler, öğretmenin öğrenciye ilişkin verdiği
geribildirimler ile akranların geribildirim verme durumları ulamlarına yönelik
incelenmiş kod ve temalar ile geribildirimin alt ulamları belirtilmiştir. Elde
edilen sonuçlara göre, bölge farketmeksizin Türkçe öğretmenleri daha çok bütün sınıfa yönelik değerlendirmeci ve sözel geribildirim vermekle birlikte
betimleyici, sürece dayalı ve yazılı geribildirim türlerini daha az
kullanmaktadırlar. Türkçe öğretmenlerinin metin işleme sürecinde geribildirim
vermenin önemine ilişkin görüş birliği sağlandığı ancak hangi beceri alanına ne
zaman, nasıl ve hangi türde geribildirim verilebileceği ile ilgili konularda
sorun yaşadıkları tespit edilmiştir.
Perbedaan Antara Parasetamol dan Ketolorak Terhadap Kadar Substansi Serum Tikus Wistar Sebagai Analgesik
Authors: Hidayat Agus Purwo , Harahap Mohamad Sofyan , Villyastuti Yulia Wahyu
Published: March 2019

Latar Belakang:Analgesik preemptif merupakan intervensi  analgesik yang dimulai sebelum stimulasi noksius muncul dalam hubungannya dengan blok perifer maupun nosisepsi sentral. Tujuanannya untuk menurunkan nyeri akut pasca trauma jaringan, mencegah modulasi nyeri pada SSP dan mencegah terjadinya nyeri kronis. Elemen penting dalam proses persepsi nyeri adalah substansi P dimana Fungsi sensoris substansi P diperkirakan berkaitan dengan transmisi informasi nyeri ke sistem saraf pusat. Parasetamol dan ketorolak sebagai obat anti-inflamasi non steroid dengan efek antipiretik dan analgetik. Berperan dalam menghambat enzim siklooksigenase. Hal ini diharapkan dapat mengetahui perbedaan kadar substansi P tikus wistar  pada keduanya sebagai pilihan analgesik preemptif. Tujuan: Mengetahui perbedaan efektivitas antara Parasetamol dan Ketorolak yang dinilai dari kadar Substansi P pada tikus Wistar sebagai analgesik preemptif. Metode: Penelitian ini merupakan eksperimental laboratorik dengan disain Rondomize Pre and Post test  control group design. Sejumlah 21 ekor tikus, dibagi menjadi tiga kelompok yang dilakukan secara acak masing-masing terdiri dari 7 ekor tikus untuk kelompok kontrol (K), 7 ekor tikus untuk kelompok perlakuan parasetamol atau K(1), 7 ekor tikus untuk kelompok perlakuan ketorolak atau  K(2). Setelah adaptasi selama 7 hari, tikus-tikus dari kelompok perlakuan maupun kontrol dilakukan pembiusan dengan menggunakan ketamin. Satu jam sebelum pembiusan, kelompok  K (1) diberi injeksi paracetamol 18 mg intravena dan kelompok K(2) diberi injeksi ketorolak  0,54 mg intravena. Sesudah terbius, bulu di sekitar punggung dicukur bersih dan didesinfeksi menggunakan betadine. Selanjutnya dibuat irisan sepanjang 2 cm dan kedalaman sampai subkutan. Luka irisan dibersihkan dan dioles larutan betadine, kemudian luka ditutup dengan lima jahitan tunggal sederhana menggunakan benang side. Selanjutnya jahitan dibersihkan, diolesi betadin dan dirawat. Paska pembedahan juga diberikan penisilin oil 15 mg. Pengambilan sampel darah untuk pemeriksaa kadar Substansi P dilakukan pada kelompok K, K(1) dan K(2) 1 jam sebelum pemberian parasetamol dan ketorolak, dan pada jam ke-4 setelah dilakukan insisi pada tikus wistar.Hasil: Dilakukan perlakuan terhadap tikus wistar, terdapat 2 ekor yang drop out, sehingga jumlah sampel yang dianalisa sebanyak 30 sampel. Pada Uji Mann-Whitney kadar substansi P dalam kelompok parasetamol dibandingkan dengan kelompok ketorolak dibentuk secara signifikan berbeda (p = 0,016; p <0,005), sedangkan kadar substansi P kelompok Parasetamol ditemukan lebih rendah dari kelompok ketorolak.Kesimpulan: Pemberian parasetamol sebagai analgesik preemptif dapat menurunkan kadar substansi P pada tikus model Wistar yang lebih signifikan dibandingkan dengan ketorolak.
GLOTTODYDAKTYCZNE OBSZARY BADAŃ NAD KOMPETENCJĄ MIĘDZYKULTUROWĄ
Authors: Róg Tomasz
Published: March 2019

As globalisation promotes cross-cultural approaches to foreign language education, the article scrutinises research on intercultural competence conducted in the field of glottodidactics. It aims at offering a possibly most comprehensive outline of our state-of-the-art knowledge of interculturality in teaching foreign languages. The following parts of the present article will look at pre- and in-service teachers, teaching materials, lesson planning, new technologies, and the age of learners, all with a view to indicating the achievements and challenges of teaching intercultural competence as an element of foreign language education.
ROLA PAMIĘCI ROBOCZEJ W NAUCE JĘZYKA OBCEGO I WIELOJĘZYCZNOŚCI
Authors: Biedroń Adriana
Published: March 2019

Working memory is now one of the most frequently studied individual differences in various fields of science, including cognitive and developmental psychology, neuroscience, and second language acquisition. It affects cognitive functioning, including all aspects of learning a foreign language, and its deficits severely impair learning outcomes. This article focuses on practical application of this knowledge (see Gregersen & MacIntyre, 2014) in a language classroom. To this end, we first present a definition of a working memory and its components altogether with their relevance for various areas of foreign language learning. This is followed by a review of research on linguistically gifted individuals, polyglots, and savants as well as bilinguals from the perspective of memory aptitude. The last section offers some pedagogical implications, such as aptitude-treatment interaction and working memory training. The article ends with suggestions for further research in this area.
Pangea
Authors: Zou Jia , Iyengar Arun , Jermaine Chris
Published: March 2019

Storage and memory systems for modern data analytics are heavily layered, managing shared persistent data, cached data, and nonshared execution data in separate systems such as a distributed file system like HDFS, an in-memory file system like Alluxio, and a computation framework like Spark. Such layering introduces significant performance and management costs. In this paper we propose a single system called Pangea that can manage all data---both intermediate and long-lived data, and their buffer/caching, data placement optimization, and failure recovery---all in one monolithic distributed storage system, without any layering. We present a detailed performance evaluation of Pangea and show that its performance compares favorably with several widely used layered systems such as Spark.
Evaluation of bond strength of cross-laminated LSL specimens under short-span bending
Authors: Gong Meng , Li Ling , Chui Ying-Hei
Published: March 2019

Mass timber panels (MTPs) have a great potential in the construction of mid- and high-rise buildings. Evaluation of the face-bond strength of MTPs is of great practical interest for this kind of products. This study aimed at developing an appropriate test procedure for evaluating the adhesive bond strength of cross-laminated laminated strand lumber (CL-LSL). Three-point short-span bending tests were conducted on two-layer asymmetric CL-LSL specimens (2LasymCL-LSL), which were adhesively bonded by two-component resins of the type polyurethane (PUR) or polyvinyl acetate (PVAc). For comparison, block shear specimens were tested as well. It was found that the 2LasymCL-LSL assembly was better suitable under the short-span bending for differentiating between good and poor bond quality of MTPs.
Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules
Authors: Mahringer Anne , Bernd Alexandra , Miller David S. , Fricker Gert
Published: March 2019

Many widespread and persistent organic pollutants, for example, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and some polychlorinated biphenyls, activate the aryl hydrocarbon receptor (AhR) causing it to translocate to the cell nucleus where it transactivates target genes, increasing expression of a number of xenobiotic metabolizing enzymes as well as some transporters. AhR’s ability to target transporters within the kidney is essentially unexplored. We show here that exposing isolated killifish (Fundulus heteroclitus) renal proximal tubules to micromolar β-naphthoflavone (BNF) or nanomolar TCDD roughly doubled the transport activity of Multidrug resistance-associated proteins Mrp2 and Mrp4, P-glycoprotein (P-gp) and Breast cancer resistance protein (Bcrp), all ATP-driven xenobiotic efflux pumps and critical determinants of renal xenobiotic excretion. These effects were abolished by actinomycin D and cycloheximide and by the AhR antagonist, α-naphthoflavone, indicating that increased transport activity was dependent on transcription and translation as well as ligand binding to AhR. Quantitative immunostaining of renal tubules exposed to BNF and TCDD showed increased luminal membrane expression of Mrp2, Mrp4, P-gp and Bcrp. Thus, in these renal tubules, the four ABC transporters are targets of AhR action.
Mg2+ homeostasis and transport in cyanobacteria – at the crossroads of bacterial and chloroplast Mg2+ import
Authors: Pohland Anne-Christin , Schneider Dirk
Published: March 2019

Magnesium cation (Mg2+) is the most abundant divalent cation in living cells, where it is required for various intracellular functions. In chloroplasts and cyanobacteria, established photosynthetic model systems, Mg2+ is the central ion in chlorophylls, and Mg2+ flux across the thylakoid membrane is required for counterbalancing the light-induced generation of a ΔpH across the thylakoid membrane. Yet, not much is known about Mg2+ homoeostasis, transport and distribution within cyanobacteria. However, Mg2+ transport across membranes has been studied in non-photosynthetic bacteria, and first observations and findings are reported for chloroplasts. Cyanobacterial cytoplasmic membranes appear to contain the well-characterized Mg2+ channels CorA and/or MgtE, which both facilitate transmembrane Mg2+ flux down the electrochemical gradient. Both Mg2+ channels are typical for non-photosynthetic bacteria. Furthermore, Mg2+ transporters of the MgtA/B family are also present in the cytoplasmic membrane to mediate active Mg2+ import into the bacterial cell. While the cytoplasmic membrane of cyanobacteria resembles a ‘classical’ bacterial membrane, essentially nothing is known about Mg2+ channels and/or transporters in thylakoid membranes of cyanobacteria or chloroplasts. As discussed here, at least one Mg2+ channelling protein must be localized within thylakoid membranes. Thus, either one of the ‘typical’ bacterial Mg2+ channels has a dual localization in the cytoplasmic plus the thylakoid membrane, or another, yet unidentified channel is present in cyanobacterial thylakoid membranes.
Study of the Drying Rate and Colour Kinetics during Stepwise Air-Drying of Apricot Halves
Authors: Xanthopoulos G. , Athanasiou A. , Sempou A. , Lentzou D. , Templalexis Ch. , Boudouvis A.G.
Published: March 2019

The drying rate and colour kinetics of apricot halves were studied during stepwise air-drying compared to continuous drying. The tested stepwise temperature profiles exhibited two successive falling rate periods, which differed from the drying rate period of the constant drying temperature profile. Three chromatic indices, namely browning index, chroma and hue were analysed. The analysis showed that treatment with ascorbic acid was more effective during the step up temperature profile, whilst its antioxidant activity was lost during the step down temperature profile due to the initially used high drying temperatures. The chromatic indices were described by a modified kinetic model, the parameters of which were estimated by theLevenberg–Marquardtoptimization algorithm and in all cases was derived R2adj≥ 0.88 and MRD < 4.88%.
MRI and bone scintigraphy for breast cancer bone metastase: a meta-analysis
Authors: Rong Yue , Ren Hong , Ding Xianjun
Published: March 2019

Objective

The aim of this study was to compare the diagnostic value of magnetic resonance image (MRI) and bone scintigraphy (BS) in the diagnosis of breast cancer bone metastases.

Methods

Searching in the databases including PubMed, Embase about the comparative study of MRI and bone scintigraphy in the diagnosis of breast cancer bone metastases during 2000~2018. After we screened further, the extracted effective data were calculated by Meta-Disc 1.4 software.

Results

We obtained 4 articles. The pooled estimates for sensitivity of MRI, BS were 0.99 (95% CI, [0.95, 1.00]) and 0.93 (95% CI, [0.88, 0.97]) respectively; For specificity were 0.99 (95% CI, [0.95, 1.00]) and 0.86 (95% CI, [0.79, 0.92]) respectively. The AUC of SROC curve for MRI and BS were 0.9948 and 0.9675 respectively.

Conclusion

MRI remains to be a satisfactory method for the diagnosis of breast cancer bone metastases and should first be considered for patients.
Crystal structure of catena-poly[diaqua-bis(3-carboxy-5-methoxybenzoato-κO)-(1,2-bis(imidazol-1-yl)ethane-κ2
N:N′)cobalt(II)], C26H28CoN4O12, [Co(C9H6O5)2(H2O)2(C8H10N4)]
Authors: Han Min-Le
Published: March 2019

C26H28CoN4O12, triclinic, P1̄ (no. 2), a = 6.5186(10) Å, b = 9.4111(14) Å, c = 12.1777(18) Å, α = 79.365(2)°, β = 77.535(2)°, γ = 89.226(2)°, V = 716.66(19) Å3, Z = 1, R
gt(F) = 0.0304, wR
ref(F
2) = 0.0778, T = 296.15 K.
Crystal structure of 4-tert-butyl-1-(2,6-dimethylphenyl)-1H-1,2,3-triazole, C14H19N3
Authors: Yerima Iliya B. , Zamisa Sizwe J. , Bala Muhammad D.
Published: March 2019

C14H19N3, orthorhombic, Pca21 (no. 29), a = 22.2821(8) Å, b = 10.8464(4) Å, c = 10.8509(4) Å, V = 2622.5(2) Å3, Z = 8, Rgt
(F) = 0.0318, wR
ref(F
2) = 0.0865, T = 100(2) K.
Thermografie zur Detektion von CFK-Schäden – Quantitativer Vergleich der Lock-in- und Puls-Phasen-Thermografie
Authors: Ekanayake Sarah , Wiedbrauck Dennis , Schäferling Marielouise , Häfner Benjamin , Schmitt Robert H. , Lanza Gisela
Published: March 2019

Die aktive Thermografie wird zur Detektion von Schäden in kohlenstofffaserverstärkten Kunststoffen (CFK) verwendet. Aufgrund des bildgebenden und tomografischen Messverfahrens wird eine zerstörungsfreie Prüfung von CFK-Schäden ermöglicht, wie sie z. B. die Serienproduktion von Fahrzeugen fordert. Das indirekte Messverfahren misst die IR-Strahlen infolge einer aktiven Anregung des Prüfobjektes. Anregungsformen, welche im industriellen Umfeld Anwendung finden, sind die sinusförmige Lock-in und die pulsförmige Puls-Phasen Thermografie. In beiden Verfahren wird die erfasste Wärmestrahlung mittels Fast Fourier Transformation in ein Phasenbild überführt. Die quantitative Auswertung erfolgt anhand der gemessenen Phasenwerte und des Phasenbildes.

Während die Lock-in Thermografie den Vorteil der Rauschunterdrückung und Detektion von tieferliegenden Schäden bietet, kann durch die Puls-Phasen Thermografie eine zeiteffizientere und somit wirtschaftlichere Messung erfolgen. In diesem Beitrag wird eine automatisierte Auswertung von Bildaufnahmen mittels Lock-in und Puls-Phasen Thermografie entwickelt und ein quantitativer Vergleich beider Verfahren hinsichtlich messtechnischer und wirtschaftlicher Kriterien der Schadensdetektion von CFK-Strukturen durchgeführt.
Re-reading Westin
Authors: Austin Lisa M.
Published: March 2019

Alan Westin’s work Privacy and Freedom remains foundational to the field of privacy, and Westin is frequently cited for his definition of privacy as control over personal information. However, Westin’s full definition of privacy is much more complex than this statement, describing four states of privacy (solitude, intimacy, anonymity, and reserve) that one achieves through physical or psychological means. The “claim” of privacy involves negotiating a balance between a desire for disclosure and social participation and a desire for withdrawal into one of the “states” of privacy. Influencing this adjustment process are social norms (and surveillance to enforce social norms), environmental conditions, and the curiosity of others. In this Article, I draw upon this complexity in order to reread Westin’s definition of privacy as a claim of control over personal information and use this rereading to understand how the law should protect and promote privacy in the twenty-first century. I argue that the law should focus on securing meaningful privacy choices rather than on individual control over personal information. Meaningful choice requires that our informational infrastructure, and the social practices that it enables, make states of privacy available for choice along with the means of attaining them. To enable such meaningful individual choice, we need to shift our attention from a focus on individuals to a more systemic focus on our public norms and built infrastructure. Otherwise we risk protecting a narrow understanding of individual control, while ignoring a more general and systematic erosion of privacy.
A Process-based Approach to Informational Privacy and the Case of Big Medical Data
Authors: Birnhack Michael
Published: March 2019

Data protection law has a linear logic, in that it purports to trace the lifecycle of personal data from creation to collection, processing, transfer, and ultimately its demise, and to regulate each step so as to promote the data subject’s control thereof. Big data defies this linear logic, in that it decontextualizes data from its original environment and conducts an algorithmic nonlinear mix, match, and mine analysis. Applying data protection law to the processing of big data does not work well, to say the least.

This Article examines the case of big medical data. A survey of emerging research practices indicates that studies either ignore data protection law altogether or assume an ex post position, namely that because they are conducted after the data has already been created in the course of providing medical care, and they use de-identified data, they go under the radar of data protection law. These studies focus on the end-point of the lifecycle of big data: if sufficiently anonymous at publication, the previous steps are overlooked, on the claim that they enjoy immunity. I argue that this answer is too crude. To portray data protection law in its best light, we should view it as a process-based attempt to equip data subjects with some power to control personal data about them, in all phases of data processing.

Such control reflects the underlying justification of data protection law as an implementation of human dignity. The process-based approach fits current legal practices and is justified by reflecting dignitarian conceptions of informational privacy.
Effect of Overload and Tapering on Individual Heart Rate Variability, Stress Tolerance, and Intermittent Running Performance in Soccer Players During a Preseason
Authors: Figueiredo Diego H. , Figueiredo Diogo H. , Moreira Alexandre , Gonçalves Helcio R. , Stanganelli Luiz C.R.
Published: March 2019

Figueiredo, DH, Figueiredo, DH, Moreira, A, Gonçalves, HR, and Stanganelli, LCR. Effect of overload and tapering on individual heart rate variability, stress tolerance, and intermittent running performance in soccer players during a preseason. J Strength Cond Res 33(5): 1222–1231, 2019—This study evaluates the weekly natural log of the root-mean-square difference of successive R-R intervals (lnRMSSDmean), its coefficient of variation (lnRMSSDcv), training load (TL), stress tolerance (ST), and changes in intermittent running performance in response to a 2-week overload (OL) followed by a 1-week taper (TP) during a preseason. Additionally, we determined the relationships between these variables. Ultra-short lnRMSSD, psychometric responses, and ratings of perceived exertion were evaluated daily among 16 under-19 soccer players. At the end of each training phase, the athletes performed the Yo-Yo Intermittent Recovery test level 1 (Yo-Yo). Group analysis showed a decrease in lnRMSSDmean and ST, increases in lnRMSSDcv, and decreases in the Yo-Yo during OL, with a return to baseline levels and a trivial increase in the Yo-Yo during TP. Small to very large correlations were found between lnRMSSDmean and lnRMSSDcv values, with changes in Yo-Yo, TL, monotony, and strain during the preseason (r values ranging from −0.27 to 0.82). No correlation was found between lnRMSSD responses and ST. During OL, athletes with decreases in lnRMSSDmean and increases in lnRMSSDcv accumulated higher perceived TL, with higher monotony and overall stress, and presented a decrease in ST and intermittent running performance, interpreted as a negative adaptation in response to the maintenance of higher TL. During TP, these responses were reversed, leading to an increase in intermittent running performance. In addition, subjective measures of ST may be used to provide early indicators of training adaptation in soccer players.
Violência contra a mulher: a percepção dos graduandos de Enfermagem
Authors: Sobrinho Natália Costa , Kasmirsck Cristine , Soares Joannie  Soares Dos Santos Fachinelli , Pinheiro Monalisa Da Silva , Fioravanti Junior Geferson Antonio
Published: March 2019

Objetivo: conhecer as percepções dos graduandos em Enfermagem sobre violência contra a mulher. Métodos: estudo qualitativo realizado com 16 graduandos em Enfermagem entre abril e junho de 2016. Dados coletados por entrevista e realizada a análise de conteúdo. Resultados: foram determinadas como categorias: entendimento sobre violência de gênero, abordagem da violência de gênero na formação dos graduandos, percepção sobre a atuação do enfermeiro na atenção às mulheres em situação de violência e considerações sobre o atendimento ideal à mulher em situação de violência. Considerações finais: a violência e a desigualdade de gênero são percebidas pelos acadêmicos. O papel do enfermeiro é destacado nas habilidades de comunicação e acolhimento. Os graduandos não se identificam como parte da equipe de saúde que receberá a mulher em situação de violência e percebem o tema no currículo da graduação. Estudos semelhantes contribuirão com a discussão sobre a violência contra a mulher.
Características evidenciadas em recém-nascidos de gestantes hipertensas e diabéticas: revisão sistemática da literatura
Authors: Albrecht Cristiane Carla , Zanesco Camila , Ribeiro Maiara Vanusa Guedes , Fadel Cristina Berger , Silva Débora Tavares Resende e
Published: March 2019

Objetivo: evidenciar quais são as repercussões no leito vascular e as características dos neonatos de gestantes com Síndromes Hipertensivas Gestacionais e/ou Diabetes Mellitus Gestacional. Método: trata-se de uma revisão sistemática de literatura, as buscas da pesquisa foram realizadas no mês de julho do ano de 2017, nas bases de dados da Literatura Latino-Americana do Caribe em Ciências da Saúde e na National Library of Medicine. Os dados foram tabulados em planilhas do Excel, sendo aplicada a análise de conteúdo. Resultados: os recém-nascidos de mães hipertensas estiveram relacionados a prematuridade e baixo peso para a idade gestacional, enquanto os recém-nascidos de mães diabéticas são relacionados a uma maior idade gestacional ao nascimento e peso considerado grande para a idade gestacional. Considerações finais: salienta-se a importância do acompanhamento através do pré-natal desde os primórdios da gestação, como medida protetiva à saúde materno-infantil.
A realização de intercâmbio no doutorado em enfermagem: um relato de experiência
Authors: Bardaquim Vanessa Augusto , Dias Ernandes Gonçalves
Published: March 2019

Objetivo: relatar a experiência discente de pós-graduação de Enfermagem em Programa de intercâmbio internacional. Método: trata-se de um relato de experiência, sobre a participação no programa de Doutorado Sanduíche, realizado por meio de concessão de bolsa do Programa de Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, entre a Escola de Enfermagem de Ribeirão Preto, São Paulo e a Universidade Laval, Quebec, entre agosto a dezembro de 2017. Resultados: participação em cursos, palestras e eventos, aluna ouvinte em disciplinas relacionadas à prática da enfermagem. Estratégia de aprendizagem baseada em problemas, as atividades de ensino foram realizadas em forma de apresentações audiovisuais, discussões em sala de aula, atividades em laboratório, trabalho em equipe, material multimídia, videoconferências, tutoriais e plataforma web. Considerações Finais: o intercambio é oportunidade para agregar valores, aprimorar o currículo e ampliar o conhecimento, além de conhecer diferentes linhas de pesquisas e teorias voltadas para a área da saúde.
Cortical Electrocorticogram (ECoG) Is a Local Signal
Authors: Dubey Agrita , Ray Supratim
Published: March 2019

Electrocorticogram (ECoG), obtained by low-pass filtering the brain signal recorded from a macroelectrode placed on the cortex, is extensively used to find the seizure focus in drug-resistant epilepsy and is of growing importance in cognitive and brain–machine-interfacing studies. To accurately estimate the epileptogenic cortex or to make inferences about cognitive processes, it is important to determine the “spatial spread” of ECoG (i.e., the extent of cortical tissue that contributes to its activity). However, the ECoG spread is currently unknown; even the spread of local field potential (LFP) obtained from microelectrodes is debated, with estimates ranging from a few hundred micrometers to several millimeters. Spatial spread can be estimated by measuring the receptive field (RF) and multiplying by the cortical magnification factor, but this method overestimates the spread because RF size gets inflated due to several factors. This issue can be partially addressed using a model that compares the RFs of two measures, such as LFP and multi-unit activity (MUA). To use this approach for ECoG, we designed a customized array containing both microelectrodes and ECoG electrodes to simultaneously map MUA, LFP, and ECoG RFs from the primary visual cortex of awake monkeys (three femaleMacaca radiata). The spatial spread of ECoG was surprisingly local (diameter ∼3 mm), only 3 times that of the LFP. Similar results were obtained using a model to simulate ECoG as a sum of LFPs of varying electrode sizes. Our results further validate the use of ECoG in clinical and basic cognitive research.

SIGNIFICANCE STATEMENTBrains signals capture different attributes of the neural network depending on the size and location of the recording electrode. Electrocorticogram (ECoG), obtained by placing macroelectrodes (typically 2–3 mm diameter) on the exposed surface of the cortex, is widely used by neurosurgeons to identify the source of seizures in drug-resistant epileptic patients. The brain area responsible for seizures is subsequently surgically removed. Accurate estimation of the epileptogenic cortex and its removal requires the estimation of spatial spread of ECoG. Here, we estimated the spatial spread of ECoG in five behaving monkeys using two different approaches. Our results suggest that ECoG is a local signal (diameter of ∼3 mm), which can provide a useful tool for clinical, cognitive neuroscience, and brain–machine-interfacing applications.
Teaching Authentic Soil & Plant Science in Middle School Classrooms with a Biochar Case Study
Authors: Pressler Yamina , Hunter-Laszlo Mary , Bucko Sarah , Covitt Beth A. , Urban Sarah , Benton Christina , Bartholomew Michelle , Morrison Amanda J. , Foster Erika J. , Parker Sylvia D. , Cotrufo M. Francesca , Moore John C.
Published: March 2019

We designed two NGSS-aligned middle school classroom experiments to investigate the effects of biochar on plant growth and soil respiration. Biochar is a carbon-rich material, produced by heating organic matter under limited oxygen, that is added to soils to improve fertility, to promote plant growth, and as one possible strategy to help mitigate climate change. The experiments offer an ideal case study for students learning fundamentals of soil and plant interactions. Soils and biochar are accessible, are connected to global issues such as agriculture and climate change, and are the focus of ongoing research in soil science. These classroom experiments promote authentic science because students design replicated experiments, collect and analyze data, discuss variability in the data, and interpret their results in the context of recent research.
MECHANISMS OF ENDOCRINE DISEASE: Sarcopenia in endocrine and non-endocrine disorders
Authors: Borba Victoria Zeghbi Cochenski , Costa Tatiana Lemos , Moreira Carolina Aguiar , Boguszewski Cesar Luiz
Published: March 2019

Objective

This paper reviews the main mechanisms, diagnostic criteria, treatment options and available data on sarcopenia in endocrine and non-endocrine disorders. The literature notes the presence of sarcopenia as a comorbid condition or a complication of another clinical situation and not a disease that only affects elderly patients.

Method

We performed a literature review, focusing on the following: mechanisms related to sarcopenia in elderly patients, and sarcopenia as it presents in the context of chronic and endocrine diseases; diagnostic tools and methods; aspects of sarcopenia and treatment options specific to chronic diseases and endocrine disorders respectively.

Results

Sarcopenia in chronic and endocrine disorders shares many mechanisms with sarcopenia affecting elderly patients, but certain diseases can have a predominant aspect that leads to sarcopenia. The prevalence of sarcopenia varies, depending on different diagnostic criteria, from around 12 to 60% in chronic illnesses and 15 to 90% in endocrine disorders. The interplay between sarcopenia, chronic diseases and elderly patients requires further study, to clarify the impact of each, in terms of prognosis and mortality.

Conclusion

Awareness of the presentation of sarcopenia in the context of other diseases and ages (and not just the elderly) is fundamental to ensure that preventive measures can be deployed.
Chronic Medication Use in Children Insured by Medicaid: A Multistate Retrospective Cohort Study
Authors: Feinstein James A. , Hall Matt , Antoon James W. , Thomson Joanna , Flores Juan Carlos , Goodman Denise M. , Cohen Eyal , Azuine Romuladus , Agrawal Rishi , Houtrow Amy J. , DeCourcey Danielle D. , Kuo Dennis Z. , Coller Ryan , Gaur Dipika S. , Berry Jay G.
Published: March 2019

BACKGROUND AND OBJECTIVES:

Little is known about the use of chronic medications (CMs) in children. We assessed the prevalence of CM use in children and the association of clinical characteristics and health care resource use with the number of CMs used.

METHODS:

This is a retrospective study of children ages 1 to 18 years using Medicaid from 10 states in 2014 grouped by the annual number of CMs (0, 1, 2–4, 5–9, and ≥10 medications), which are defined as a dispensed ≥30-day prescription with ≥2 dispensed refills. Trends in clinical characteristics and health care use by number of CMs were evaluated with the Cochran-Armitage trend test.

RESULTS:

Of 4 594 061 subjects, 18.8% used CMs. CM use was 44.4% in children with a complex chronic condition. Across all children, the most common CM therapeutic class was neurologic (28.9%). Among CM users, 48.8% used multiple CMs (40.3% used 2–4, 7.0% used 5–9, and 0.5% used ≥10). The diversity of medications increased with increasing number of CMs: for 1 CM, amphetamine stimulants were most common (29.0%), and for ≥10 CMs, antiepileptics were most common (7.1%). Of $2.3 billion total pharmacy spending, 59.3% was attributable to children dispensed multiple CMs. Increased CM use (0 to ≥10 medications) was associated with increased emergency department use (32.1% to 56.2%) and hospitalization (2.3% to 36.7%).

CONCLUSIONS:

Nearly 1 in 5 children with Medicaid used CMs. Use of multiple CMs was common and correlated with increased health care use. Understanding CM use in children should be fundamentally important to health care systems when strategizing how to provide safe, evidence-based, and cost-effective pharmaceutical care to children.
Functional identification and subcellular localization of NAD kinase in the protozoan parasite Giardia intestinalis
Authors: Contreras Rodríguez Luis Ernesto , Jutinico Shubach Laura Laura Marcela , García Castañeda Javier Eduardo , Ramírez Hernández María Helena
Published: March 2019

Nicotinamide adenine dinucleotide phosphate (NADP) is an essential biomolecule that participates in the redox homeostasis and synthesis of signaling compounds. NAD kinase (NADK) (EC 2.7.1.23 / 2.7.1.86) is the only enzyme capable of synthesizing NADP. This study offers an approach to the NADP metabolism in the parasite Giardia intestinalis, the etiologicalagent of giardiasis, a disease of high prevalence in America, Asia and Africa. Through bioinformatics tools a NADK enzyme candidate was identified, whose tertiary structure modeling demonstrated distinctive and universal motifs of characterized NADKs. The corresponding recombinant protein (His-GINADK) was expressed in Escherichia coliBL21 (DE3) and its partial purification was achieved by nickel affinity chromatography. Functional identification, which showed NADP synthesis, was completed through enzymatic assays evaluated by RP-HPLC. A cytosolic localization of the endogenous GINADK enzyme was observed in trophozoites throughout indirect immunofluorescence analysis, using polyclonal antibodies produced in mice by its immunization with the His-GINADK protein, purified from inclusion bodies. Taken together, our results contribute to the understanding of the NADP metabolism and the physiological role of NADK in the Giardiamodel.
A checklist of Rubiaceae species from Eastern Samar, Visayas, Philippines
Authors: Ordas Jorge Anton D. , Pinarok Neil Alejandro A. , Romeroso Roanne B. , Alejandro Grecebio Jonathan D. , Banag-Moran Cecilia I.
Published: March 2019

Samar Island is a center of botanical wealth throughout the Philippine archipelago. However, floristic knowledge of the island is deficient and most of its forested areas remain largely unexplored. Thus, floristic surveys of Rubiaceae members were made on Eastern Samar, located in Visayas, Philippines. Collections were conducted from June 2013 to June 2017 within 5 municipalities: Borongan, Balangkayan, Taft, Guiuan, and Llorente. In total, 59 species belonging to 31 genera representing 21 tribes of the family were recorded. The most species-rich tribes belong to Naucleeae, Psychotrieae, and Spermacoceae, with 10, 8, and 6 species, respectively. Of the 59 species recorded, 37 are endemic to the Philippines. Twelve species are listed as threatened species based on its proposed IUCN category and DAO 2017-11. This study presents an enumeration of Rubiaceae found on selected forested areas of Eastern Samar, Philippines.
12 tips for developing inter-professional education (IPE) in healthcare
Authors: Hill Elaine , Morehead Erin , Gurbutt Dawne , Keeling Joanne , Gordon Morris
Published: March 2019

This article was migrated. The article was marked as recommended. As healthcare increases in complexity there is growing awareness that interprofessional teamwork underpins safe and effective care delivery. However, in order to collaborate in interprofessional teams, health professionals must also train in them. Despite increasing interest in IPE amongst healthcare educators, and positive comments from students, barriers to its implementation remain. The authors of this article come from different healthcare professions and have overcome the challenges of developing IPE to devise several successful activities. This article outlines the educational benefits of IPE and provides guidance for surmounting obstacles to its implementation, supported by examples from our own experience.
Living on the streets: An integrative review about the care for homeless people
Authors: Koopmans Fabiana Ferreira , Daher Donizete Vago , Acioli Sonia , Sabóia Vera Maria , Ribeiro Crystiane Ribas Batista , Silva Carine Silvestrine Sena Lima da
Published: March 2019

ABSTRACT Objective: To identify essential elements in care practices for the Homeless Persons in the context of Primary Health Care and verify evidence and strength of recommendation for health decision-making. Method: Integrative literature review, using Health Descriptors, keywords and "MeSH terms" in the databases: LILACS, PubMed Centre and Web of Science. Results: Twenty-two scientific papers were selected and grouped into three categories: Understanding of the Other, Support Network and Emancipatory Care. The study identified important elements for the development of care, such as understanding Homeless Persons, valuing network care and Emancipatory Care. Conclusion: There was a need for further studies and research on the subject, which would make it possible to construct more equitable and inclusive health policies and actions for this population that needs very unique elements in care practices.
Active teaching model to promote critical thinking
Authors: Carbogim Fábio da Costa , Oliveira Larissa Bertacchini de , Toledo Melina Mafra , Diaz Flávia Batista Barbosa de Sá , Bittencourt Greicy Kelly Gouveia Dias , Püschel Vilanice Alves de Araújo
Published: March 2019

ABSTRACT Objective: To present the experience of elaboration and implementation of the Active Teaching Model to Promote Critical Thinking (MEAPC), associated to Problem-Based Learning (PBL), for undergraduate students in Nursing. Method: Case report on the experience of the educational intervention (MEAPC + PBL) with undergraduate students in Nursing, in a 20-hour course on Basic Life Support (BLS). The MEAPC was validated by judges to guide the analysis of clinical cases. Critical Thinking (CT) skills were assessed using the California Critical Thinking Skills Test. Result: The educational intervention took place in two phases: elaboration and implementation, allowing not only the production of knowledge about BLS, but also the development of CT and exchange of experiences for teaching-learning. Conclusion: The association of the MEAPC to the PBL in the course of BLS organized the learning, gave opportunity to acquire knowledge and to stimulate the skills of the CT.
Modelagem do uso da Terra e Efeitos de Mudanças na Produtividade Agrícola entre 2008 e 2015
Authors: Faria Weslem Rodrigues , Haddad Eduardo Amaral
Published: March 2019

Resumo O artigo apresenta os resultados dos efeitos sistêmicos da mudança no padrão da produtividade agrícola entre 2008 e 2015. Para isso foi utilizado um modelo de equilíbrio geral computável (EGC) com especificação detalhada do uso da terra. Tal análise representa avanços no sentido de contribuir tanto para a modelagem econômica com uso da terra quanto na investigação dos impactos econômicos sistêmicos da mudança no padrão espacial da produtividade agrícola no Brasil. Os resultados indicaram que essa mudança teve efeitos positivos sobre o PIB real nacional e da maioria dos estados, contribuindo também para a redução das disparidades regionais.
O prazer e a dor na adicção sexual: vicissitudes do masoquismo
Authors: Klier Ney , Winograd Monah
Published: March 2019

Resumo A adicção sexual pode ser definida como quadro psicopatológico no qual o sexo é buscado de forma incontrolável, desenfreada, a despeito dos prejuízos emocionais, sociais e profissionais que suscita no cotidiano do adicto. Após o frenesi, a excitação e a adrenalina em ceder aos próprios impulsos urgentes e vorazes, o sex-addict percebe-se incapaz de gerenciar suas atuações sexuais, sendo consumido por sentimentos de vazio, fracasso e desespero. A problemática do prazer sexual “além do princípio de prazer”, conjugada à da dor psíquica, nos conduz a uma interrogação mais rigorosa sobre a dimensão do masoquismo na vida subjetiva e sua relação com os estados destrutivos da psicossexualidade. Neste artigo, fundamentado sob o viés da psicanálise, procuramos examinar a estreita relação entre autodestruição e satisfação libidinal nos fenômenos próprios do quadro em questão.
Response of vital functions, Apgar and cortisol in the prognosis of vigor against neonatal factors of lambs
Authors: Fagundes Glaucia B. , Nascimento Dayana Maria , Santiago Marcela R. , Neves Camila A. , Silva Cleidson M.G. , Oba Eunice , Arrivabene Mônica , Cavalcante Tânia V.
Published: March 2019

ABSTRACT: The management of lambs during the neonatal period has been studied in several researches due to the vital and hormonal organic adaptations undergone by the calf after birth. However, gender, number of pups and type of delivery play an important role in understanding neonatal vigor. The study of these groups with the monitoring of clinical evolution and cortisol metabolism becomes an indispensable subsidy for a better understanding of this neonatal phase, aiming to minimize the losses generated. The objective of this study was to evaluate the influence of gender, number of pups and type of delivery in the prognosis of neonatal vigor of lambs through clinical and cortisol diagnosis. Thirty crossbred Santa Inês lambs with Dorper in the neonatal phase were divided into three groups: male and female, number of pups (single and twin) and type of delivery (eutocic and dystocic). In each group, clinical evaluation of heart and respiratory rate, rectal temperature, Apgar score and weight were performed; and with the exception of cortisol, all evaluations were performed at fifteen and sixty minutes, as well as at twelve and twenty-four hours. In addition, blood samples were collected for cortisol dosage obtained in two moments at fifteen and sixty minutes using the radioimmunoassay technique. Among the three experimental groups related to lamb vigor, the heart rate was the only one that showed lower mean values (P<0.05) at twenty-four hours in the male group 90.00±20.20bpm, twins 96.44±20.02bpm and eutocic 93.25±18.11bpm. Differences in respiratory rate values were observed in the eutocic group (64.00±14.75mpm) at twenty-four hours. In the group of males there was a significant reduction in body temperature during the evaluation moments (P<0.05). Lambs from the group of twins showed lower body weight during the evaluations. At both times the analysis of serum cortisol was less than at sixty minutes. It was concluded that soon after the birth there were marked changes in the physiological parameters and weight of Santa Inês lambs, but were not enough to cause negative effects on the vigor of the neonates, indicating the occurrence of effective neonatal adaptation capacity in this species.