bluuebunny/crossref_metadata_2025 huggingface dataset:
PENERAPAN KONSEP AL-MAŚULĪYAH DALAM MEMINIMALISIR DAMPAK SOSIAL USAHA PETERNAKAN AYAM RAS PETELUR
Authors: Harfinawati Harfinawati Fina
Published: January 2023

Penelitian ini membahas mengenai penerapan konsep al-maśulīyah dalam meminimalisir dampak sosial peternakan ayam ras petelur di Desa Lompu Kecamatan Cina. Tujuan penelitian ini untuk  menjawab permasalahan tentang dampak sosial yang ditimbulkan dengan adanya usaha peternakan ayam ras petelur,  implementasi konsep al-maśulīyah bagi pelaku usaha peternakan ayam ras petelur, dan faktor-faktor yang mendukung dan menghambat implementasi konsep al-maśulīyah bagi pelaku usaha peternakan ayam ras petelur di Desa Lompu Kecamatan Cina. Penelitian ini merupakan penelitian lapangan (kualitatif) dengan pendekatan ekonomi syariah dan pendekatan sosiologis. Sumber pengumpulan data menggukan data primer dan sekunder. Penelitian ini melakukan teknik pengumpulan data menggunakan metode observasi, wawancara, dan dokumentasi. Pengolahan data dilakukan dengan cara melakukan pengumpulan data secara menyeluruh lalu memilah data yang relevan dengan penelitian kemudian menyajikan data dan melakukan verifikasi dan kesimpulan.Hasil penelitian menunjukkan bahwa pertama, dampak sosial usaha peternakan ayam ras petelur di Desa Lompu yaitu terjadinya interaksi yang menyebabkan tumbuhnya solidaritas antara pelaku usaha dengan masyarakat serta adanya motivasi berternak masyarakat sekitar peternakan. Kedua, implementasi konsep al-maśulīyah bagi pelaku usaha telah dilaksakan tetapi dari segi hukum tidak mematuhi peraturan yang berlaku pada industri pengunggasan dan segi etika telah melaksanakan tanggung jawabnya bukan hanya terhadap diri sendiri namun bertanggung jawab terhadap masyarakat dan alam (lingkungan) dengan melakukan upaya-upaya dalam meminimalisir dampak sosial tersebut. Ketiga, faktor pendukung implementasi konsep al-maśulīyah yaitu penduduk mayoritas Islam, adanya pengetahuan dalam menjalankan usaha, adanya kesadaran pelaku usaha, adanya komunikasi yang baik dan faktor penghambatnya yaitu ketidakpuasan masyarakat dan perubahan kondisi cuaca. Kata Kunci: al-maśulīyah (Tanggung jawab), Dampak Sosial
MOTIVASI KERJA DAN ETOS KERJA DALAM PEMENUHAN KEBUTUHAN EKONOMI KELUARGA PERSPEKTIF EKONOMI SYARIAH
Authors: Sumarni Sumarni Manni
Published: January 2023

Penelitian tersebut membahas tentang motivasi kerja dan etos kerja dalam pemenuhan kebutuhan ekonomi keluarga dalam perspektif ekonomi syariah pada kurir di Watampone. Tujuan penelitian ini untuk menjawab permasalahan tentang motivasi kerja dalam pemenuhan kebutuhan ekonomi keluarga kurir di Watampone, etos kerja dalam pemenuhan kebutuhan ekonomi keluarga kurir di Watampone, dan perspektif ekonomi syariah pada motivasi kerja dan etos kerja dalam pemenuhan kebutuhan ekonomi keluarga kurir di Watampone. Penelitian ini merupakan penelitian lapangan (Field Research) dengan pendekatan teologis normatif dan pendekatan sosiologis. Jenis data yang digunakan adalah data primer dan sekunder. Penelitian ini menggunakan metode observasi, wawancara, dan dokumentasi. Pengolahan data dilakukan dengan cara melakukan pengumpulan data secara menyeluruh lalu memilah data yang relevan dengan penelitian kemudian menyajikan data dan melakukan verifikasi dan kesimpulan. Hasil penelitian menunjukkan bahwa, pertama, motivasi kerja dalam pemenuhan kebutuhan ekonomi keluarga pada kurir di Watampone bahwa motivasi kerja sangat mempengaruhi semangat kerja para kurir di Watampone. Adanya motivasi para kurir dapat mendorong untuk bekerja dalam memenuhi kebutuhan ekonomi keluarga. Kedua, etos kerja dalam pemenuhan kebutuhan ekonomi keluarga pada kurir di Watampone menunjukkan bahwa adanya etos kerja yang baik dapat menentukan keberhasilan kerja kurir dalam pemenuhan kebutuhan ekonomi keluarga kurir di Watampone. Ketiga, motivasi kerja dan etos  kerja kurir di Watampone dalam perspektif ekonomi syariah telah sesuai dari beberapa aspek yaitu prinsip tauhid, prinsip keadilan (keseimbangan), prinsip tolong-menolong dan prinsip tanggung jawab.
The Iconsistency of Czech Presidential Diplomacy and the Growth of Czech Foreign Trade with China
Authors: Cuhlova Renata , Nesiba Jiri
Published: January 2023

This paper analyzes the relation between the diplomatic activity of Czech presidents and the economic trend of bilateral trade between the Czech Republic and China during 1993-2019. The investigation is based on a statistical survey of diplomatic steps and economic figures. Although the policy of the first Czech President Václav Havel (1993-2003) was cautious towards China, Czech-Chinese bilateral trade exchange was nevertheless consistent and relatively balanced. In the period of President Václav Klaus (2003-2013), after the accession of the Czech Republic to the EU, the trend of trade balance continued to the detriment of Czech exports despite the trade volume growth. However, the decline of exports to China was similarly observed in other Central European countries. That was also a period when Czech presidential diplomatic acts towards China became more numerous. In the period of President Miloš Zeman (2013-until now), the diplomatic activity of the Czech President increased significantly according to the number of official visits and signed documents. Simultaneously, there has been a significant decline in Czech exports and Chinese reinvested profits in the Czech Republic. The authors substantiate the findings by quantitative analysis and describe the development of Czech presidential diplomacy from the perspective of Czech-Chinese economic relations during 1993-2019 as inconsistent.
Tingkat Penggunaan Gadget (Smartphone) dan Prestasi Belajar Siswa
Authors: Ole Anita Amelia , Kodina Lilis
Published: January 2023

The development of the era is also followed by technological developments in terms of communication, this can be seen by the increasing sophistication of smartphones, causing students to be more interested in these sophisticated objects than having to study to achieve learning achievements at school. The purpose of this study is to see the level of use of smartphone gadgets and student achievement. Haomasan and Nofharina (2018) mean that teenagers' use of smartphone gadgets varies, some are due to the sophistication of their features, being able to access the internet quickly, easily accessing social media, as a means of entertainment, and helping to complete school assignments. This research uses quantitative research. The results of this conclusion indicate that the use of smartphone gadgets is placed in the frequent category with the sum of the average or mean values ​​(M) = 3.97. and the results of student achievement in science subjects are in the very good category. The advice from this study is to maintain the level of student achievement, but don't forget to control the time when using smartphone gadgets because it will hurt student achievement if you use smartphone gadgets too often.
Penerapan Model Problem Based Learning Berbantuan Media Power Point untuk Meningkatkan Hasil Belajar PKn pada Siswa Kelas V SDN Wonokusumo VI/45
Authors: Astuti Widji , Arifah Siti , Nurhamami Sri Setik
Published: January 2023

This study aims to determine the increase in Civics learning outcomes through the problem-based learning model assisted by power point media. The research subjects were fifth grade students at SDN Wonokusumo VI/45 for the academic year 2022/2023, with a total of 32 students consisting of 16 female students and 16 male students. This research was conducted in 2 cycles, each cycle consisting of two meetings with one meeting for the implementation of learning and one meeting for the end of the cycle test. The design in each of these cycles consists of four stages, namely starting with planning, then taking action, observing, and finally reflecting. Research data on student civics learning outcomes were collected using the usual multiple choice objective test method with four options. Data were analyzed using quantitative descriptive statistics. The results showed an increase in PPKn learning outcomes for fifth grade students. This can be seen from the average in cycle I, which increased from 62.25 to 84 in cycle II. Thus it can be concluded that the problem based learning model assisted by power point media can improve the learning outcomes of fifth grade students at SDN Wonokusumo VI/45.
Sejarah Peradaban Islam di Pulau Madura
Authors: Zikra Alfiandi , Irham M. Iqbal , Wanto Sugeng
Published: January 2023

In the book Negarakertagama which was written by Mpu Prapanca when under the rule of King Hayamwuruk from the Majapahit kingdom in 1365 AD, initially Madura was an archipelago with Java. Some argue that the islands of Madura and Java were separated in 929 AD due to a volcanic eruption. Islam entered Madura intensively around the 15th century AD along with the waning influence of the Majapahit kingdom in East Java. In the 16th century Madura was divided into two regions. first, west madura whose area is Arosbaya which later became Bangkalan and Sampang. The two East Madura, namely Sumenep and Pamekasan. The history of the development of Islam in Bangkalan began with the reign of Panembahan Pratanu, who had the title Weak Dhuwur. While the spreaders of Islam in Sumenep include Sunan Padusa. The spread of Islam on the island of Madura was spread through trade, not by war. This is in accordance with the Islamic religious principle of spreading peace. The war that occurs is only to maintain what already exists, not to hold something that doesn't yet exist.
Vertical Fiscal Imbalance and Public Service Expenditure: Effects on Economic Growth Before and During Covid-19 Pandemic
Authors: Suyanto
Published: January 2023

Since 2020, Indonesia has been facing the Covid-19 pandemic for 2 years. Many impacts caused by the Covid-19 pandemic, especially on the economy, have led to a recession. Regional revenues are disrupted during a recession so local governments depend on central government transfer funds. From these issues, researchers suspect that there was a change in the decentralization conditions in East Java province during the Covid-19 pandemic as it was the province with the second largest GDP and has also experienced the greatest impact in Indonesia. This research method uses multiple linear regression with cross-sectional data from 38 district/city data units in East Java province. The results of this study are that the Decentralization Fund, Civil Service Capital Expenditure and the Human Development Index did not change before and during the Covid-19 pandemic. While the vertical fiscal imbalance has a positive influence on economic growth before the Covid-19 pandemic, the vertical fiscal imbalance has no influence on economic growth. This shows that there is another shift in priority in the use of central government finances, as state money is refocused and reallocated to deal with Covid-19. This makes development programs in other health sectors postponed.
MIMPI BESAR ANTROPOLOGI HUKUM
Authors: HENDRA BENI
Published: January 2023

Antropologi secara etimologis berasal dari bahasa Yunani. Kata Anthropos berarti manusia dan logosberarti ilmu pengetahuan. Jadi antropologi adalah ilmu yang mempelajari manusia. Dalam ilmu antropologi hukum dipelajari mengenai peran, status atau kedudukan,nilai, norma juga kebudayaan. Semua ini sangat erat kaitannya dengan ilmu antropologi hukum. Sebelum berdirinya Komunisme, magistrat-magistrat Tiongkok, misalnya, tidak berurusan dengan menginterpretasi dan menerapkan aturan hukum untuk kasus-kasus konflik yang terjadi, namun menggunakan aturan hukum hanya sebagai pedoman teladan-teladan yang sangat berguna, tetapi tidak harus diteladani dalam kasus konkrit.
MAKALAH ANTROPOLOGI HUKUM MENJADI CORAK ILMU HUKUM
Authors: Zaki Qory Evands A.
Published: January 2023

Antropologi secara etimologis berasal dari bahasa Yunani. Kata anthropos berarti manusia dan logos berarti ilmu pengetahuan. Jadi antropologi adalah ilmu yang mempelajari manusia. Dalam ilmu antropologi hukum dipelajari mengenai peran, status atau kedudukan,nilai, norma juga kebudayaan. Semua ini sangat erat kaitannya dengan ilmu antropologi hukum. Sebelum berdirinya Komunisme, magistrat-magistrat Tiongkok, misalnya, tidak berurusan dengan menginterpretasi dan menerapkan aturan hukum untuk kasus-kasus konflik yang terjadi, namun menggunakan aturan hukum hanya sebagai pedoman teladan-teladan yang sangat berguna, tetapi tidak harus diteladani dalam kasus konkrit. Dalam antropologi hukum tidak dapat membatasi diri pada isi peraturan-peraturan hukum dan bentuk- bentuk sanksinya, tapi yang perlu diketahui dengan jelas adalah proses pembentukan hukumnya
Academic writing and AI: Day-4 experiment with mindsponge theory
Authors: Quang-Loc Nguyen , Nguyen Minh-Hoang , La Viet-Phuong
Published: January 2023

To check the ability of AI to identify precise and detailed scientific information, I experiment with how accurate AI recognizes scientific terms, their origins, meanings, and usages, and whether the accuracy increases over time
Experiment ended
Authors: Evans Isabelle
Published: January 2023

Financial Support for Research in Vietnam
Perencanaan Bisnis Otomotif di Tengah Masa Resesi 2023
Authors: Valois Pierrezeus Reinard
Published: January 2023

Berdasarkan beberapa sumber terpercaya hingga Kementrian Keuangan Indonesia mengatakan bahwa akan terjadi resesi ekonomi pada tahun 2023 mendatang. Resesi ekonomi sendiri merupakan keadaan perekonomian suatu negara mengalami masalah dan berada di kondisi yang rawan (buruk). Hal ini terjadi ketika aktivitas ekonomi dalam suatu negara mengalami penurunan yang cukup drastic dalam jangka yang lama, sehingga menimbulkan dampak buruk dan menyulitkan masyarakat satu negara. Banyak sekali hal?hal yang dapat menyebabkan terjadinya resesi ekonomi dalam suatu negara.
Revisiting the link between the Sustained Attention to Response Task (SART) and daily-life cognitive failures
Authors: Schorrlepp Leonie , Schepers Annika Maria , de Vries Juriena , de Kloe Tamara , van der Linden Dimitri , Bijleveld Erik
Published: January 2023

In this research project we examine the relationship between errors of commission on the Sustained Attention to Response Task (SART) and scores on the Cognitive Failures Questionnaire (CFQ). The goal was to assess the ecological validity of the SART for a fatigued sample to establish its relevance for evaluating fatigue interventions given the susceptibility of fatigued individuals to attentional failures. SART errors of commission were positively associated with CFQ scores and this finding remained after controlling for fatigue level, age, and SART reaction times. However, this association was only found in the subsample of employees, not in university students. The three subscales of the CFQ showed the same pattern of findings. Our results imply that, when using the SART to draw conclusions about everyday life, it is crucial to consider the characteristics of one’s sample and control for relevant confounding variables.
Pentingnya Pameran bagi Pelaku Bisnis
Authors: Maharani Puan Ayu
Published: January 2023

Pameran bisnis atau yang sering kita dengar dengan expo adalah event yang dirancang untuk mempertemukan pemasok produk, peralatan industri dan jasa di suatu tempat dimana para peserta dapat mendemonstrasikan dan mempromosikan produk dan jasa yang mereka tawarkan (Hall, 2003). Pameran bisnis atau pameran lainnya pada umumnya terbuka untuk umum sebagai media iklan, karena memang tujuan kegiatan ini adalah memperkenalkan produk kepada masyarakat agar mereka tertarik dan kemudian membelinya (Yahya dan Lubis, 2017). Pelaku bisnis juga dapat bertemu langsung dengan pelanggan dan pembeli yang terjadwal waktu dan tempatnya.
FILSAFAT HUKUM SEBAGAI CAHAYA HUKUM DARI KEHIDUPAN MANUSIA
Authors: rahmadinivelga
Published: January 2023

Filsafat adalah studi tentang seluruh fenomena kehidupan dan pemikiran manusia secara kritis dan dijabarkan dalam konsep mendasar. Filsafat tidak didalami dengan melakukan eksperimen-eksperimen dan percobaan-percobaan, tetapi dengan mengutarakan masalah secara persis, mencari solusi untuk itu, memberikan argumentasi dan alasan yang tepat untuk solusi tertentu. Akhir dari proses-proses itu dimasukkan ke dalam sebuah proses dialektika. Untuk studi falsafi, mutlak diperlukan logika berpikir dan logika bahasa
ANTROPOLOGI HUKUM DLM PANDANGAN HUKUMM ADAT
Authors: hugo m
Published: January 2023

bahwa wawasan antropologi hukum lebih luas dri pada hukum adat karena tdk hanya memperhatikan hukum di indonesia tetapi juga bersifat komparatif sehingga hukum ditinjau sebagai gejala yg bersifat lintas budaya
Experiment ended
Authors: Robinson Jonny
Published: January 2023

The Cost of Science and Ethics in Research
Experiment ended
Authors: Robinson Jonny
Published: January 2023

The Benefits of Human Consumption of Insects
Executive Functioning and the Interplay of Internalizing and Externalizing Symptoms – Understanding Developmental Dynamics Through Panel Network Approaches
Authors: Freichel René , Pfirrmann Janine , de Jong Peter J. , Cousijn Janna , Franken Ingmar H.A. , Oldehinkel Albertine , Veer Ilya , Wiers Reinout
Published: January 2023

Early adolescence is an important transition period during which many mental disorders emerge. The interplay between different internalizing and externalizing mental health problems in adolescence is poorly understood at the within-person level. Executive functioning (EF) in early adolescence has been shown to constitute a transdiagnostic risk factor, but the specificity of the associations between different domains of EF and internalizing/externalizing mental health problems remains unclear. Leveraging data from a large longitudinal panel study of adolescents (TRAILS, n > 1641) assessed at ages 11, 13, and 15, we investigated the network dynamics of different internalizing and externalizing symptoms. We showcase the use of two novel methodological panel network approaches: cross-lagged panel network models (CLPN) and graphical vector autoregressive (GVAR) models. Moreover, we used hierarchical regression models to investigate prospective associations between different measures of EF (working memory, sustained attention, shifting attention) and broadband transdiagnostic dimensions (internalizing/externalizing symptoms). Depressive symptoms emerged as an important bridge connecting clusters of internalizing and externalizing mental health problems in the cross-sectional networks. Importantly, depressive symptoms predicted a range of other internalizing symptoms (i.e., panic, somatic problems, separation anxiety, general anxiety, social phobia) over time, in particular during early adolescence. In contrast, social phobia symptoms were most strongly predicted by other symptoms. Externalizing symptoms, such as oppositional-defiant problems and inattention/hyperactivity predicted depressive and OCD symptoms at the within-person level respectively. We identified important feedback loops with reciprocal associations between different anxiety symptoms (e.g., separation anxiety – general anxiety, and panic symptoms – somatic problems). Different facets of EF assessed at age 11, in particular sustained attention, showed weak but significant prospective associations with internalizing and externalizing symptoms at age 13 and 15. Our findings speak to the importance of attending to depressive symptoms in early adolescence to prevent a spiral of different internalizing symptoms from arising later on.
Transfer of Statistical Learning from Passive Speech Perception to Speech Production
Authors: Murphy Timothy , Holt Lori L. , Nozari Nazbanou
Published: January 2023

One’s own speech can be affected when communicating with a speaker with a different accent. Despite the strength of anecdotal evidence for perception-production transfer, the nature of transfer has remained elusive. Results have been highly variable both regarding the acoustic properties that transfer between speakers and the characteristics of the speakers who show transfer. The current study investigates perception-production transfer through the lens of dimension-based statistical learning. Participants passively listened to a short sequence of acoustically variable minimal pair (beer/pier) speech segments conveying either an accent or typical English acoustics, made a perceptual judgment to an ambiguous Test stimulus and then repeated the Test stimulus. In the Canonical condition, F0 and voice onset time (VOT) of /b/ and /p/ covaried according to their usual pattern in English. In the Reverse condition, the correlation was reversed to create an ’accent’ with speech input regularities atypical of English. Perceptual categorization showed down-weighting of F0 in the Reverse vs. the Canonical condition. Critically, this down-weighting transferred to production, with systematic changes to F0 when speakers repeated the Test stimulus in the Reverse vs. the Canonical condition. Both findings were robust in male and female participants. These results indicate that the mapping of acoustics to speech categories is rapidly adjusted by short-term input regularities experienced across passive listening and that these adjustments transfer robustly to speech production, regardless of sex.
Maltese as a Merger of Two Worlds: A cross-language approach to phonotactic classification
Authors: Nieder Jessica , Tomaschek Fabian
Published: January 2023

Maltese is a prime example of a language that emerged through extensive language contact, joining the two linguistic worlds of Semitic and Italo-Romance languages. Previous studies have shown this shared origin on the basis of hands-on comparative methods. The present study aims at demonstrating this shared origin by employing computational methods. For this, we trained a simple two-layer neural network on Tunisian and Italian nouns, i.e. thelanguages that Maltese emerged from. We used the trained network to classify Maltese nouns as either of Tunisian or of Italian origin. Overall, the network is capable of correctly classifying Maltese nouns as belonging to either of the original languages. Moreover, we find that the classification depends on whether a noun forms a sound or broken plural. While our results replicate previous comparative studies, they also demonstrate that a more fine grained classification of a language’s origin can be based on individual words and morphological classes.
Teachers Perception Towards Pre and Post- Teaching Activities in English Language Teaching
Authors: Sharma Madhu , Jnawali Laxman
Published: January 2023

The present study aims to find out the “Teachers’ Perception Towards Pre and Post-Teaching Activities in English Language Teaching”. The main focus of the study was directed on perception of higher level English teacher towards pre and post-teaching activities in English Language Teaching. The study, being an attitudinal study, is believed to be relevant in offering a realistic picture of the effectiveness of pre and post- teaching activities in ELT. The study was carried out using both primary and secondary sources of data. For primary data, firstly higher-level English teachers have been selected through random sampling procedure. The study was confined with in Rupandehi district to find out the effectiveness of pre and post- teaching activities in ELT. It was found that the higher-level teachers are highly positive towards the teachers’ pre and post-teaching activities in ELT.
Role of Digital Technologies for Sustainable Innovation and Value Creation: A Narrative Review
Authors: VK Rajan Kumar
Published: January 2023

The purpose of this review paper is to examine the role of cutting-edge technologies in various aspects of supply chain processes as a part of a strategic plan for driving sustainable innovation. Furthermore, the study also explores the impact of digitization on modernizing supply chain operations from an industry 4.0 perspective for value creation. The study implies a narrative qualitative review for the interpretation of analyzed data from the selected articles and is based on analytical, and logical reasoning to determine patterns, relationships, or trends within the realm of the chosen subject matter for this study. The literature reveals that the implication of cutting-edge technologies as a strategic part of supply chain operations is significantly important for sustainable innovation and value creation of the company. The findings of the study will have implications for the supply chain managers for creating value for their organizations, stakeholders, and customers. Moreover, the study will also provide the essential knowledge for the development of the theory in the same domain for future researchers.
Analysis of Educational Impact in the Doda Region of Jammu and Kashmir
Authors: Hussain Gufran
Published: January 2023

Jammu and Kashmir's ECE services have taken a "Great Leap Forward" since the central government released the Outline of National Plan for Medium- and Long-term Education Reform and Development (hereafter referred to as "the Plan") and the State Council's Several Opinions on the Current Development of Early Childhood Education (hereafter referred to as "the Opinions") in 2010. Based on the findings of this study, it is clear that an integrated strategy is necessary for fostering youth development in rural Jammu and Kashmir. By taking this tack, we can increase the likelihood that students and their communities benefit economically, socially, and culturally from their schooling. Adult education and youth development are synonymous with literacy since both focus on helping people who have not finished their formal education for various reasons become productive members of society by completing their education and achieving their developmental goals. That's why literacy's importance extends to both the training of adults and the development of children.
Plasma levels of galectin-3 in residents of the Podillya region of Ukraine without signs of cardiovascular pathology carriers of different variants of the coding gene (LGALS-3, rs 2274273)
Authors: Polishchuk T. V.
Published: January 2023

Annotation. The purpose of the study is to investigate the plasma level of galectin-3 in postmenopausal women without signs of cardiovascular pathology and its possible association with the structural and functional parameters of the myocardium in carriers of different polymorphic variants of the coding gene (LGALS-3, rs2274273). 67 women of postmenopausal age (average age 56.43±0.64 years) without signs of cardiovascular pathology residents of the Podillya region of Ukraine were examined. In addition to the general clinical examination, the research used the enzyme immunoassay method to determine the level of galectin-3 in blood plasma, genotyping of the LGALS3 gene at the rs2274273 locus by means of polymerase chain reaction, and ultrasound of the heart. Statistical processing of the obtained results was carried out using the package of statistical programs SPSS, STATISTICA v. 10.0. By means of correlation analysis with the calculation of Spearman's rank correlation coefficients (r), an assessment of the possible association of the plasma level of the biomarker and the structural and functional indicators of the heart was carried out. The critical value of the significance level (p) was ≤0.05. In the examined population of women, there was no significant difference between the frequency of occurrence of the GA and GG genotypes carriers of the galectin-3 gene locus rs2274273: 49.25% (n=33) and 40.30% (n=27), respectively (p>0.05). The AA genotype variant was found in 10.45% (n=7) of individuals, which is significantly less frequent than both the GA and GG genotypes (p<0.01). The frequency of distribution of genotypes corresponded to the Hardy-Weinberg equilibrium. The average level of galletin-3 in blood plasma in women was 6.68±0.30 ng/ml, it was within the generally accepted norms and did not reliably differ from the corresponding indicators in men of the same region. No significant difference in plasma concentrations of galectin-3 was found in carriers of different polymorphic variants of the galectin-3 gene. Correlation between the level of galectin-3 in the blood plasma and most indicators of intracardiac and systemic hemodynamics in women without cardiovascular pathology was not found. In the future, it is planned to study the formation of prerequisites for chronic heart failure (CHF) in women with EH based on indicators of the plasma level of galectin-3 in carriers of polymorphic variants of the coding gene (LGALS-3, rs2274273).
Optimization of pharmacotherapy of gestational hypertension
Authors: Vaskiv O. V. , Hryhorenko A. P. , Horbatiuk O. H. , Dudikova L. V. , Shatkovska A. S. , Binkovska A. N.
Published: January 2023

Annotation. Hypertension in pregnant women disimprove the placental function, impairs fetal development and has an adverse effect on the condition of a woman. Usually dopegyt is used to treat gestational hypertension. However, it reduces the microcirculation of blood in the placenta, causing or increasing pre-existing placental dysfunction. Therefore, the aim of the research is to optimize the method of gestational hypertension pharmacotherapy in pregnant women with a set of infusion drugs including pentoxifylline, arginine hydrochloride with levocarnitine and reosorbilact to prevent fetoplacental dysfunction and perinatal pathology in this case. We examined 73 pregnant women, among whom we distinguished 3 groups: first group (n = 30) - pregnant women with GH, who, along with the basic therapy with dopegyt received a complex of infusion solutions (pentoxifylline, a solution containing arginine hydrochloride and levocarnitine, drug reosorbilact); second group (n=20) - patients with gestational hypertension who received only basic therapy with dopegyt; control group (n=23) - women with physiological pregnancy. Studies of the clinical effectiveness of the proposed treatment were evaluated by cases of prevention of perinatal pathology (intrauterine growth restriction of the fetus (IUGR), premature birth, etc.) and the results of clinical, laboratory and instrumental research methods. Criteria for inclusion in the study were: the presence of blood pressure ≥150/100 mm Hg, dopegyt, gestational age from 28 to 36 weeks, singleton pregnancy. Examination of pregnant women was performed using standard clinical, laboratory and instrumental (Doppler ultrasounds) research methods. The analysis of the obtained data was performed using the program “STATISTICA 5.5”. Established that in patients who received our treatment regimen, there was a significant reduction in the development of placental dysfunction (OR 0.30, 95 % CI [0.12-0.74], p=0.009), fetal IUGR (OR 0.33, 95 % CI [0.12-0.96], p=0.042), acute fetal distress (OR 0.25, 95 % CI [0.075-0.83], p=0.02), weakness of childbirth (OR 0,19, 95 % CI [0.04-0.82], p=0.03), reducing the risk of perinatal CNS damage (OR 0.22, 95 % CI [0.05-0.99], p=0.049 ) and reducing the risk of cephalohematoma (OR 0.25, 95 % CI [0.075-0.83], p=0.024).
Andragogy in higher medical education: features of implementation in fundamental and clinical disciplines
Authors: Zaichko N. V. , Shevchuk S. V. , Zaichko K. O. , Samborska I. A. , Shtatko O. I.
Published: January 2023

Annotation. The article summarizes the main aspects of andragogy - the science of adult education, considers key terms, and characterizes the principles and methods of andragogy. The regulatory documentation regulating the organization and requirements for the development of andragogical competence of teachers was analyzed; electronic resources of PubMed were studied; Google Academy with depth of bibliographic search 2012-2022; the experience of applying aspects of andragogy in the scientific and pedagogical work of the departments of biological and general chemistry and the department of internal medicine №2 of National Pirogov Memorial Medical University, Vinnytsya was analyzed and summarized. It is shown, that the effectiveness of the modernization of higher medical education in Ukraine, requires the formation of a new generation of scientific and pedagogical workers who are capable of self-improvement, self-development, and lifelong education. A scientific and pedagogical worker in the field of higher medical education must understand the basic principles of andragogy, constantly develop and improve his andragogy competence, and master the methods of mentoring, moderation, and facilitation. The application of the principles of andragogy in higher medical education is aimed at the formation of a competitive specialist capable of continuous professional development throughout life based on an atmosphere of freedom, creativity, tolerance, responsibility, an individual educational trajectory, and equal opportunities for subjects of study. The implementation of andragogic technologies and methods in institutions of higher medical education depends on educational goals and can vary in fundamental and clinical disciplines. Prospects for further research are the development of normative documents and recommendations on the methodology of andragogy for employees of a higher medical school.
The level of subjective control of students and the peculiarities of its changes in the conditions of the use of distance and classroom forms of organization of educational activities
Authors: Vergeles T. M.
Published: January 2023

Annotation. The purpose of the scientific work was to determine the characteristics of changes in the criterion indicators of the level of subjective control (LSC) of modern students of medical institutions of higher education in the conditions of using remote (on-line) and auditorium (off-line) forms of organization of educational activities. Scientific research was conducted on the basis of National Pirogov Memorial Medical University, Vinnitsya. Psychohygienic evaluation of the leading characteristics of the LSC was carried out based on the use of a personal questionnaire developed by Rotter in the modification of Bazhin, Golinkina and Etkind. The statistical analysis of the obtained results was carried out on the basis of the application of the standard package of multivariate statistical analysis application programs “Statistica 6.1” (license number AXX910A374605FA) using descriptive statistics procedures. In the course of research, it was found that in the structure of the leading features of the students' personality RSC, indicators of the LSC in the field of achievements, LSC in the field of health and illness, LSC in the field of interpersonal relations, and LSC in the field of family relations prevailed. Instead, the indicators of general internality of LSC, LSC in the field of failures and, which became too unexpected a phenomenon, LSC in the field of educational relations should be considered the least pronounced. It was necessary to pay attention to quite interesting phenomena that were characteristic of various formats of the organization of educational activities. Thus, in the conditions of using the distance form of education, at least several objective positive significant phenomena were noticed – a significant increase of (p(t)<0.05-0.01) with the online form of organization of the educational process in the values of LSC indicators in the field of health I and diseases and in the field of achievements. At the same time, in the conditions of using the auditorium form of education, such positively significant phenomena as a significant increase (р(t)<0.05-0.01) with the off-line form of organization of the educational process of the values of LSC indicators in the field of interpersonal relations and LSC in the field of failures. In the future, the obtained data should be used during the development of methods of comprehensive hygienic assessment of the state of adaptive resources and functional capabilities of the students’ organism, which take into account the peculiarities of the development of psychophysiological functions and personality traits in the conditions of using different forms of organization of the educational process.
Acute decompensation of liver cirrhosis and acute-on-chronic liver failure: diagnostic and prognostic criteria, treatment strategy
Authors: Tkachenko T. V. , Shevchuk S. V. , Masik N. P.
Published: January 2023

Annotation. In recent years, new data have been obtained regarding the course of liver cirrhosis (LC) and ways of its decompensation. Acute-on-chronic liver failure (ACLF) is a newly identified separate clinical syndrome that develops in 30% of patients with acute LC decompensation, characterized by hepatic and extrahepatic organ failure and high short-term mortality. The aim of this review was to describe the clinical and prognostic value of acute LC decompensation and ACLF, the pathophysiological mechanisms of their development, and existing diagnostic and treatment approaches. A search in the PubMed database using the keywords "liver cirrhosis, acute decompensation of cirrhosis, acute-on-chronic liver failure" allowed us to select 46 sources published in 2005-2022. This review discusses new concepts about the stages of the course of compensated and decompensated LC, which differ in the severity of portal hypertension, the number and type of decompensation events, and patient survival. The clinical and prognostic value of acute LC decompensation, which manifests as recent ascites, bleeding, hepatic encephalopathy, bacterial infection, and requires hospitalization of the patient, was considered. The trajectories of the further development of acute decompensation, which are represented by stable or unstable decompensated LC, pre-ACLF, and ACLF, were discussed. Current European diagnostic criteria for ACLF, severity criteria for ACLF, and tools for predicting patient survival were reviewed. The latest data on the pathophysiological role of portal hypertension, systemic inflammation, metabolic disorders, and immunopathological cell damage in the development of organ failure in ACLF was given. The existing therapeutic measures and promising methods of treatment of patients with acute LC decompensation and ACLF were considered.
Pathology of coronary arteries in children and its clinical significance
Authors: Dudnyk V. M. , Zborovska O. O. , Demianyshyna V. V. , Popov V. P.
Published: January 2023

Annotation. Coronary insufficiency and associated ischemic heart disease are most common among adult patients, while life-threatening myocardial ischemia can develop in childhood and clinically debut as a sudden death syndrome. In children and young adults, the most frequent cardiac causes of sudden death syndrome include hypertrophic cardiomyopathy, coronary artery anomalies, other phenotypes of myocardial pathology, and myocarditis. Anomalies of the coronary arteries cause significant difficulties in diagnostics because they have a wide clinical polymorphism – from asymptomatic variants to severe myocardial dysfunction due to ischemia, and also require special knowledge and skills when using modern methods of imaging the heart and its structures. The work is devoted to the analysis of the etiology of coronary artery disease in childhood and is aimed at increasing the awareness of the medical community about this problem. The Cochrane Library, Pub Med and Google Scholar reference databases were used for the review. 84 articles were studied and analyzed, 29 sources were included in the review. Myocardial ischemia in childhood and associated severe myocardial dysfunction are most often the result of congenital anomalies of coronary artery development, coronary artery pathologies in the composition of other congenital heart defects, coronary artery damage in Kawasaki disease, and coronary insufficiency in patients with hypertrophic cardiomyopathy. It is important to note that coronary vessel anomalies can often be asymptomatic and not detected during routine clinical examination, but manifest themselves in young and even adult life in the form of acute myocardial ischemia and cardiogenic shock against the background of complete well-being. During echocardiographic screenings it is necessary to pay attention to the anatomy of the coronary arteries. Also a multidisciplinary approach to the management of children with diseases in which coronary artery damage is possible is necessary.
Current problems and persprectives of the treatment of cartilage injuries using mesenchimal stem cells
Authors: Fishchenko V. О. , Botsul О. V. , Shuvalova N. S. , Deryabina О. G. , Iaremyn S. Yu. , Fishchenko О. V. , Bielieha O. V.
Published: January 2023

Annotation. Since standard methods of treatment of cartilage trauma and inflammatory diseases lack effectiveness, at present one of the most promising strategies is mesenchymal stem cell transplantation. Despite the successes in this field, many issues, such as the selection of the tissue-source of mesenchymal stem cells (MSCs) and their optimization or modification in culture in order to achieve the maximum therapeutic effect, remains an actual task for both global and domestic scientists. The purpose of the study is to prepare a review of literature sources for the period 2004-2022 (in the vast majority on publications of the last five years) and to systematize new data on the biological characteristics of MSCs from various tissue sources, which are used in strategies for the treatment of cartilage lesions tissues, to analyze existing problems and further prospects, as well as potential ways of optimizing MSC cultivation methods to increase their regenerative potential. A study of 49 sources that met the inclusion criteria was carried out. A significant variety of strategies for the use of MSCs in animal models and in clinical practice was revealed. The main mechanisms ensuring the therapeutic effect of MSCs have been determined and can be used as criteria for optimizing cellular material. However, it was found that the question of the effectiveness of the use of differentiated MSCs, the selection of the tissue-source of MSCs, and the specifics of the use of MSCs from neonatal sources remains open. Thus, the analysis of literary sources revealed further promising ways to improve the therapeutic efficiency of MSC grafting in a wide range of cartilaginous lesions. There is a need to research the effects of MSCs from neonatal tissues, and especially the umbilical cord. This will become possible due to experimental research that will be carried out in the future.
The current regime of heat waves and their impact on the yield of cereal crops in Ukraine
Authors: Semenova I. G.
Published: January 2023

Heat waves are one of the most dangerous meteorological phenomena, the manifestations of which have become more frequent in all regions of the globe in recent decades. Due to excessively high temperatures persisting for a long time, heat waves cause heat stress in living organisms and plants, and negatively affect various sectors of the national economy. Although the mechanism of heat wave formation is well known, the question of determining and predicting the intensity and duration of these processes in advance, as well as the areas of their propagation, remains open, including due to the lack of unified concept of a heat wave. This study analyzed the spatiotemporal distribution of extremely warm days and heat waves for the period 1996-2021 in 16 regions of Ukraine, where the production of the main agricultural crops (winter wheat, spring barley, corn) is concentrated. The analysis was performed using the surface skin temperature Ts, which contains information about the temperature of both the canopy and ground surface.

It was found that during the study period, the number of extremely warm days increased in all regions of the country and in all seasons of the year, with the most significant increase occurring in the last decade in winter and autumn. The warmest year was 2020, when the number of extremely warm days in some regions reached 100-106 per year. The frequency of heat waves at the end of the study period almost doubled compared to the beginning, reaching an average of 8-10 cases per year. The average seasonal frequency of heat waves was 4-5 cases in summer and 2-4 cases in other seasons. The longest heat waves lasting 17-19 days were recorded in all agro-climatic zones in August 2010. In other seasons, the maximum duration of heat waves did not exceed 10-14 days.

Statistical assessment of the relationship between the seasonal number of extremely warm days and the grain yield crops showed that an increase in these days in the spring leads to decrease in the yield crops of winter wheat and spring barley; in summer this negative impact is observed for corn.
Semester Credit System Program Evaluation at MTsN 2, Kediri City
Authors: Munir Muhammad Syahrul , Muhtadin Muhammad Akhsanul , Septiansyah Moch. Agung Lukman
Published: January 2023

Education is needed by every student, so education must be in accordance with the needs needed by students. As is currently developing, namely education with a semester credit system (SKS). We often hear SKS in tertiary institutions as a unit of measurement for learning load. However, now SKS has begun to be implemented in junior high and high school. This study aims to find out how to evaluate the context of SKS program at MTsN 2 Kota Kediri, how to evaluate the input of SKS program at MTsN 2 Kota Kediri, how to evaluate the process of implementing SKS program at MTsN 2 Kota Kediri, how to evaluate the product of SKS program at MTsN 2 Kota Kediri. In this study a qualitative approach was used and the type of evaluation research was the CIPP model (Context, Input, Process, Product). Collecting data in this study using observation, documentation and in-depth interviews. The results of this study indicate that schools organize SKS to provide services to students according to their talents, interests and abilities, but there are problems in context evaluation, namely the understanding of participants and students' parents of SKS program is still lacking, in terms of assessing human resource input it still needs to be improved , in terms of process evaluation there were still difficulties in preparing and distributing Independent Learning Activity Unit books, and in terms of product evaluation it was considered good because there were students who won and could study in 2 years.