bluuebunny/crossref_metadata_2025 huggingface dataset:
Deciphering the Role of AMPK in Regulating Integrin Profile of Tumor-Derived Exosomes as a Potential Antimetastatic Strategy
Authors: Mehrabi Ayshin
Published: July 2024

Introduction: Cancer cell adapt their metabolic activity to survive in stressful environments with limited nutrients and oxygen. To sense and respond to nutrient cues, cells rely on a “fuel gauge” protein known as AMP-activated protein kinase (AMPK). While previous work has largely focused on AMPK’s role in cell metabolism, its role in metastasis is poorly defined. Interestingly, AMPK also regulates the membrane trafficking of integrins – key proteins in cell adhesion and migration. Recent studies have also shown that circulating integrins in exosomes are predictive of metastasis. Therefore, understanding the biology of AMPK signaling on the exosomal integrin profile not only allow for better cancer treatments but also help developing a potential predictive biomarker. I hypothesize that AMPK activation alters the integrin profile of exosomes in breast and endometrial cancer. Methods: Breast and endometrial cancer cells, MDA-MB-231 and HEC-1 respectively, will be cultured in full nutrient media conditions. 48 hours before exosome harvest, the media will be changed to minimal specialized media for extracellular vesicles (EV) collection. To induce AMPK activation, cells will be treated with limiting concentrations of glucose and glutamine, or with metabolic poisons 2-deoxyglucose (2-DG) and oligomycin. Total Exosome IsolationTM (TEI) solution will be used to enrich released exosomes that will be subjected to mass spectrometry to analyze the exosomal integrin profiles. Anticipated Results: Exosomes secreted from MDA-MB-231 and HEC-1 cells are expected to contain different exosomal integrin profile in both basal and induced AMPK activation conditions. It is anticipated that integrin subunits that promote metastatic and survival signaling such as αvβ5, α6β4, α6β1, will be upregulated in exosomes following AMPK activation. This could suggest tumor cells adapting to nutrient insufficiency by AMPK activation may present a more aggressive exosomal integrin profile to support cancer progression. Discussion: Understanding how metabolic cues such as nutrient insufficiency impact integrin content of tumour-derived exosomes can help identify novel metabolic drug targets to limit pro-survival and pro-metastatic signaling in primary breast tumors. Conclusion: This study investigates how AMPK activation modulates the exosomal integrin profile in breast and endometrial cancer cells, potentially uncovering predictive biomarkers and therapeutic targets for metastatic cancers.
Christian-Māoriesque – A Transcultural Pictorial Artform
Authors: Longhurst Christopher Evan
Published: July 2024

This exploration develops the field of intercultural aesthetics by exploring the use of Māori motifs used by non-Māori artists, and looking at the use of those motifs in the context of Christian art.[i]  It surveys a selection of paintings that blend Māori and Christian motifs, and critically evaluates their interculturality. It then looks at how intercultural artworks of religious subject matter can create an instance of pictorial transculturality. An identity for an artistic cross-fertilization between Christianity, Māoritanga, and Pākehā culture is linked with the defining principle of transculturality, and a new term is suggested to categorise this identity, the Christian-Māoriesque.
 
[i] By “non-Māori artists” I mean all artists who do not identify as Māori, that is, who do not have whakapapa.
Environmental Politics and Policy in Aotearoa New Zealand
Authors: Wu Fengshi
Published: July 2024

With an ensemble of experts, Maria Bargh and Julie L. MacArthur have done a timely service to the communities of academic research, teaching-and-learning, and public policymaking by editing the book Environmental Politics and Policy in Aotearoa New Zealand. It is timely as we witness another year of record-breaking dramatic weather and climate-related disasters worldwide. More than ever, all sectors of society at large are compelled to learn more about the environment we live in, the histories of the lands, waters, and forests around us, interconnections across complex geological, ecological, and socio-economical systems, and, ultimately, the relationship between individuals and the future of Aotearoa and beyond.
Gifted and “Possessed”: Reading and Writing the Adaptable Frame
Authors: Cronin Jan
Published: July 2024

This article explores Patrick Evans’s neglected novel Gifted, arguing that Evans, as novelist, wilfully forges, inhabits and defends the same authorial ground his criticism of the work of Janet Frame assailed for decades. Positioning Gifted as part penance, part reparation, part justification for Evans’s literary criticism, this essay negotiates the dynamics of equivocal blend that characterise Evans’s “gifted” relationship with Frame and finds, within Gifted, an enactment of the continuum between paratext and adaptation.
Korean Celebrity Brand Ambassador in Indonesia Advertisement: A Study Exploring Figure of Speech and Communication Strategies
Authors: Ronauli Maria Margaretha , Ansas Velayeti Nurfitriana , Lubis Arif Husein
Published: July 2024

Effective communication in advertisements hinges on clarity and relatability. Choosing the right figures of speech and communication strategies can significantly enhance the effectiveness of an advertisement. This study aims to identify the types of figures of speech and communication strategies technique used in advertisements featuring South Korean celebrity brand ambassadors for Indonesian product. Using a descriptive qualitative method based on the theories of Kim Wook Dong (2002) and Tatang (2016), data source were collected from advertisements on social media YouTube by using the method of listening to the note-taking technique. An interactive analysis model was used to analyze the data. Based by predetermined criteria, data was reduced to a total of nine Indonesian product advertisements with containing South Korean celebrity brand ambassadors from 2016 - 2023. The findings reveal that various figures of speech and communication strategies were employed to evoke consumer emotions in conveying the message and the purpose of the advertisement. By employing figures of speech that evoke emotions, advertisers can increase the effectiveness of their campaigns by strategically selecting linguistic elements that resonate with the target audience.
India's Energy Policy and Cooperation with Russia
Authors: Kondratov D.I. ,   Institute of Economics  of the Russian Academy of Sciences,  Moscow, Russia
Published: July 2024

The relatively high growth rates of GDP and real incomes of the population compared to other Asian countries, combined with the ongoing policy of industrialization and urbanization, make India one of the most attractive markets for commodities. At the same time, India is characterized by extremely low levels of motorization and per capita consumption of many goods and services, including plastic products, which determines the potential for growth in consumption of primary energy sources. Due to the progressive increase in per capita GDP in India, the poverty level is decreasing, stimulating an increase in the number of relatively well-off citizens and, as a result, the consumption of electricity, petroleum products and other energy sources. However, due to the small reserves of fossil resources, India is in dire need of them, mainly oil and gas. Among the key areas of its economy are the oil and gas production and oil and gas processing industries. The subject of the study is India's energy policy, in particular its oil and gas market. The aim of the work is to establish prospects for cooperation between Russia and India due to the fact that the latter is a fast–growing economy and is an expanding market for fossil fuels for the needs of households and industry. The article identifies the peculiarities of the development of the fuel and energy sector of India, and establishes its energy needs. India's energy policy has been reviewed in the light of the implementation of the Paris Climate Agreement, its oil and gas reserves have been identified and directions for possible diversification of their supplies have been predicted. It is concluded that due to the sanctions imposed on Russian companies and the need to diversify the supply of natural resources, foreign economic cooperation with India is of particular interest to Russia.
Import Substitution in the High-Tech Sector as a Factor of Sustainable Development and Modernization of the Russian Transport Complex
Authors: Karpova S.V. ,   Financial University,  Moscow, Russia, Pogodina T.V. ,   Financial University,  Moscow, Russia
Published: July 2024

The relevance of the article is due to Russia's desire to counteract the sanctions imposed by the United States and its satellites and rely on its own financial and economic resources. The subjects of the research are the policy of import substitution and its impact on the modernization of the country's transport complex. The purpose of the work is to identify key problems and promising areas for the implementation of import substitution policy in high–tech sectors of the economy as factors of sustainable development and modernization of the Russian transport complex. It is noted that in order to achieve this goal, it is advisable to use an import substitution policy in high-tech industries, which are characterized by a high intensity of internal costs for research and development, a large proportion of workers with higher education, as well as higher innovation activity. It is determined that at present the modernization of the transport complex is largely determined by the development of high-tech sectors of the economy. The interrelation of sustainable economic development and the results of import substitution is substantiated, problems and promising areas of import substitution policy in high-tech sectors of the Russian economy are identified, and the degree of influence of import substitution policy on the development of the Russian transport complex is assessed. The expediency of forming responsible production has been established, which minimizes the negative impact of the activities of economic activities on the environment and allows to prevent the technological lag of the national economy and serves as the basis for the modernization of the transport complex through the use of domestic equipment and vehicles for the development primarily of aviation, rail, water and road transport.
Insuficiencia cardiaca debido a hipotiroidismo primario
Authors: Narváez Montenegro Gabriela Alexandra , Rodriguez Rodriguez Pamela Rocio , López Cajamarca Jéssica Lucía , Ordóñez Ortiz Andrea Nicole
Published: July 2024

El análisis detallado de la literatura confirma una conexión estrecha entre el hipotiroidismo primario y la insuficiencia cardíaca, señalando que el primero puede influir significativamente en el desarrollo y la progresión del segundo. Se identificaron diversos mecanismos fisiopatológicos que implican cambios en la función cardíaca y vascular, subrayando la importancia de un diagnóstico temprano y un tratamiento adecuado del hipotiroidismo para mejorar los resultados clínicos en pacientes con insuficiencia cardíaca. Se realizó una metodología de revisión bibliográfica sobre la relación entre insuficiencia cardiaca e hipotiroidismo primario y se basó en la búsqueda exhaustiva de estudios relevantes en bases de datos científicas como PubMed, Scopus y Web of Science. Se utilizaron términos de búsqueda específicos relacionados con ambas condiciones médicas, combinados con operadores booleanos para refinar los resultados. Se resalta la importancia de reconocer el hipotiroidismo como un factor de riesgo modificable en el desarrollo y la progresión de la insuficiencia cardíaca, especialmente en poblaciones vulnerables como los adultos mayores. La detección precoz y el tratamiento adecuado del hipotiroidismo pueden tener un impacto significativo en la reversión de la disfunción cardíaca y la mejora de los resultados clínicos en pacientes con insuficiencia cardíaca.
Infección por Helicobacter pylori
Authors: Aroca Aldaz María José , Narváez Montenegro Gabriela Alexandra , López Cajamarca Jéssica Lucía , Domínguez Arévalo José Haraldo
Published: July 2024

La infección por Helicobacter pylori es una condición gastrointestinal común que puede causar enfermedades como la gastritis y las úlceras pépticas, e incluso aumentar el riesgo de cáncer gástrico. Se realizó una metodología de revisión bibliográfica para la Infección por Helicobacter pylori mediante la identificación exhaustiva de estudios pertinentes utilizando bases de datos electrónicas como PubMed, Scopus y Web of Science. Se utilizaron términos de búsqueda específicos como "Helicobacter pylori", "infección por H. pylori" y "tratamiento de H. pylori" para seleccionar los artículos. Se aplicaron criterios de inclusión y exclusión para filtrar los estudios relevantes, incluyendo aquellos que abordaban la epidemiología, diagnóstico, tratamiento y resistencia antibiótica de la infección por H. pylori. Se realizó una evaluación crítica de la calidad metodológica de los estudios seleccionados y se sintetizaron los hallazgos clave para proporcionar una visión integral del estado actual del conocimiento sobre esta infección. Aunque existen métodos de diagnóstico y tratamientos efectivos, como la terapia combinada de antibióticos entre otros, persisten desafíos como la resistencia antibiótica y la recurrencia. La investigación continua es crucial para mejorar la comprensión y el manejo de esta infección bacteriana, así como para desarrollar estrategias preventivas más eficaces.
Ética y privacidad en el uso de Inteligencia Artificial en la comunicación durante urgencias obstétricas
Authors: Macías Alvia Aida Monserrate , Galardy Domínguez Yelennis , Vite Solórzano Franklin Antonio , Zambrano Santos Roberth Olmedo
Published: July 2024

La introducción de la tecnología en la atención médica ha transformado la práctica clínica, ofreciendo nuevas herramientas para mejorar el diagnóstico, tratamiento y comunicación con los pacientes. Sin embargo, surge una preocupación creciente sobre la privacidad de los datos, especialmente en áreas sensibles como la obstetricia y la ginecología. Este estudio se enfoca en revisar críticamente la literatura existente para entender cómo se abordan los aspectos éticos y de privacidad en el uso de la inteligencia artificial para la comunicación durante emergencias obstétricas, destacando su importancia en la práctica enfermera. La metodología implica una búsqueda exhaustiva de artículos en bases de datos especializadas, seleccionando estudios relevantes que aborden el tema. Se extraerá y sintetizará información sobre aspectos éticos y de privacidad en el uso de inteligencia artificial en la comunicación obstétrica. el uso de la inteligencia artificial en el ámbito de la salud, incluida la obstetricia, está en constante evolución, con aplicaciones que van desde la comunicación entre instituciones sanitarias hasta la predicción de patologías y la personalización de tratamientos. Aunque presenta múltiples ventajas, su implementación también conlleva riesgos, como la protección de datos y la comunicación eficaz. Por tanto, es esencial una formación adecuada y una colaboración entre profesionales de la salud, desarrolladores tecnológicos y usuarios para garantizar una atención de calidad centrada en el paciente, especialmente en salud femenina.
Educación inclusiva, una mirada al futuro
Authors: Piña Reinoso Liliana Elizabeth , Rodriguez Rodriguez Rosa Adela , Rodriguez Rodriguez Helio Jhon
Published: July 2024

La educación inclusiva representa un compromiso vital con la equidad y la diversidad en el ámbito educativo. Mirando hacia el futuro, su importancia radica en la creación de entornos donde cada estudiante se sienta valorado y respaldado en su aprendizaje. Esto implica no solo políticas y prácticas educativas inclusivas, sino también una transformación de actitudes y mentalidades. La formación docente, los recursos adecuados y una revisión constante de las políticas son clave en este proceso. La educación inclusiva no solo beneficia a los estudiantes con necesidades especiales, sino que enriquece la experiencia educativa de todos, fomentando la empatía y la valoración de la diversidad, y contribuye a la construcción de una sociedad más justa y equitativa. El presente trabajo de investigación se realizó mediante una metodología de revisión bibliográfica, en primera instancia se comenzó por identificar fuentes relevantes, como revistas académicas, libros y documentos oficiales de organizaciones educativas. Se establecieron criterios de búsqueda que incluyeran términos clave como "educación inclusiva", "diversidad", "equidad" y "políticas educativas". Se utilizó una combinación de bases de datos en línea y catálogos de bibliotecas para recopilar una amplia gama de estudios y opiniones expertas.
Ovario poliquístico. Diagnóstico y manejo
Authors: Cabrera Gómez Pamela Nicole , Manosalvas Hurtado Joffre Alexis , Proaño Proaño Joselyn Mishel , Carpio Garcia José Manuel
Published: July 2024

El síndrome de ovario poliquístico (SOP) es un trastorno endocrino heterogéneo que se caracteriza por la manifestación de quistes ováricos, anovulación y variación endocrina que impactan severamente la vida de una mujer. Para llevar a cabo la revisión bibliográfica sobre el síndrome de ovario poliquístico (SOP), su diagnóstico y manejo, se realizaron búsquedas exhaustivas en bases de datos científicas como PubMed, Scopus y Google Scholar. Se seleccionaron artículos publicados entre 2019 y 2024, utilizando palabras clave como "síndrome de ovario poliquístico", "diagnóstico de SOP" y "manejo de SOP". El SOP es una condición compleja con múltiples manifestaciones que requiere un enfoque integral y personalizado para su manejo. Las modificaciones en el estilo de vida, combinadas con intervenciones farmacológicas y tratamientos específicos para los síntomas, pueden mejorar significativamente la calidad de vida de las pacientes. La coordinación interdisciplinaria y el seguimiento continuo son cruciales para abordar eficazmente esta condición y sus complicaciones asociadas.
HUBUNGAN KEDISIPLINAN, MOTIVASI, DAN MINAT BELAJAR SISWA TERHADAP HASIL BELAJAR SISWA MATA PELAJARAN IPA KELAS V UPT SPF SD NEGERI DAYA 1 KECAMATAN BIRINGKANAYA KOTA MAKASSAR
Authors: Idris Muhamad , Khalik Muh. Fihris , N Jusmaniar
Published: July 2024

Penelitan ini bertujuan untuk mengetahui hubungan antara disiplin belajar, motivasi, dan minat belajar terhadap hasil belajar siswa mata pelajaran IPA kelas V UPT SPF SD Negeri Daya 1 Kecamatan Beringkanaya Kota Makassar. Jenis penelitian ini adalah penelitan korelasional dengan sampel penelitian berjumlah 30 siswa kelas V UPT SPF SD Negeri Daya 1 Kecamatan Bringkanaya Kota Makassar tahun ajaran 2022/2023. Instrumen penelian angket dan data dokumentasi dalam pengumpulan data di analisis dengan “Analisa Univariat” dan “Analisa Bivariat”. Hasil penelitan dari masing-masing variabel menunjukan bahwa ada hubungan terhadap hasil belajar siswa pada mata pelajaran IPA kelas V UPT SPF SD Negeri Daya 1 Kecamatan Bringkanaya Kota Makassar ( 0,01 < 0,05) sehingga dapat di simpulkan bahwa ada hubungan signifikan yang positif dan sangat kuat antara kedisiplinan, motivasi dan minat belajar terhadap hasil belajar pada mata pelajaran IPA kelas V UPT SPF SD Negeri Daya 1 Kecamatan Bringkanaya Kota Makassar.This research aims to determine the relationship between learning discipline, motivation and interest in learning on the learning outcomes of students in class V science subjects at UPT SPF SD Negeri Daya 1, Beringkanaya District, Makassar City. This type of research is correlational research with a research sample of 30 students in class V UPT SPF SD Negeri Daya 1 Bringkanaya District, Makassar City, academic year 2022/2023. The questionnaire research instruments and documentation data in data collection were analyzed using "Univariate Analysis" and "Bivariate Analysis". The research results of each variable show that there is a relationship with student learning outcomes in science subjects class V UPT SPF SD Negeri Daya 1 Bringkanaya District, Makassar City (0.01 < 0.05) so it can be concluded that there is a significant positive relationship and very strong relationship between discipline, motivation and interest in learning on learning outcomes in science subjects class V UPT SPF SD Negeri Daya 1 Bringkanaya District, Makassar City.
AKULTURASI BUDAYA DAN AGAMA DALAM TRADISI SAYYANG PATTU’DU PADA MASYARAKAT MANDAR DI DESA PAMBUSUANG KABUPATEN POLEWALI MANDAR
Authors: Amiruddin Nur Aidhilah Ma’rufi , Manda Darman , Idrus Idham Irwansyah , Najamuddin Najamuddin
Published: July 2024

This research aims to (i) explore and describe the process of cultural and religious acculturation in the Sayyang Pattu'du tradition in the Mandar community (ii) determine the views and meaning of the Mandar community towards the Sayyang Pattu'du tradition (iii). The research method used is descriptive qualitative. The number of informants in this study was 9 informants who were determined by considering the inclusion and exclusion criteria. Data collection techniques include observation, interviews and documentation. The research results found that (1) before Islam entered Mandar, Sayyang Pattu'du was only intended for traditional ritual events or as a means of welcoming nobles. However, after Islam entered the land of Mandar, precisely in the 16th century AD, during the 4th Balanipa king, Daetta Marra'dia, he then made children more active in reading the Koran, he announced to his people who was able to recite it. Al-Qur'an then he will be mounted on a dancing horse and paraded around the village. (2) The implementation of the Sayyang Pattu'du culture certainly has a big influence on people's lives, both from a social, religious and cultural perspective in the area. This celebration is a cultural celebration that is very meaningful and has a positive impact in the Muslim community, including the implementation of the Sayyang Pattu'du cultural celebration which can be a motivation for children to recite the Al-Quran.Penelitian ini bertujuan untuk (i) menggali dan mendeskripsikan proses akulturasi budaya dan agama dalam tradisi Sayyang Pattu’du pada masyarakat Mandar (ii) mengetahui pandangan dan pemaknaan masyarakat Mandar terhadap tradisi Sayyang Pattu’du (iii). Metode penelitian yang digunakan ialah kualitatif yang bersifat deskriptif. Jumlah informan pada penelitian ini sebanyak 9 informan yang ditentukan dengan memperhatikan kriteria inkluksi dan eksklusi. Teknik pengumpulan data dilakukan observasi, wawancara, dan dokumentasi. Hasil penelitian ditemukan bahwa (1) sebelum Islam masuk di Mandar, Sayyang Pattu’du hanya diperuntukkan pada acara ritual adat atau sebagai sarana penyambutan para bangsawan. Namun setelah Islam masuk di tanah Mandar tepatnya pada abad ke 16-M masa raja Balanipa ke-4 yaitu Daetta Marra’dia yang kemudian agar para anak-anak lebih giat dalam membaca Al-Qur’an beliau mengumumkan pada rakyatnya barang siapa yang mampu mengkhatamkan Al-Qur’an maka dia akan di naikkan di atas kuda yang menari dan di arak keliling kampung. (2) Dalam pelaksanaan budaya Sayyang Pattu’du tentu sangat berpengaruh terhadap kehidupan masyarakat, baik ditinjau dari segi sosial, agama ataupun budaya yang ada di wilayah tersebut. Perayaan ini menjadi suatu perayaan budaya yang sangat bermakna dan memiliki dampak positif di tengah-tengah masyarakat muslim diantaranya adalah pelaksanaan perayaan budaya Sayyang Pattu’du dapat menjadi motivasi bagi anak-anak untuk mengkhatamkan Al-Quran.
PERAN KESETARAAN GENDER DALAM MEMPENGARUHI KEMANDIRIAN DAN KEKUATAN PEREMPUAN BUGIS MASA KINI
Authors: Darmayanti Dyan Paramitha , Manda Darman , Sadriani Andi
Published: July 2024

Penelitian ini bertujuan untuk mengeksplorasi dampak kesetaraan gender terhadap kemandirian dan kekuatan perempuan Bugis saat ini. Peran perempuan dalam masyarakat Bugis telah lama menjadi bagian penting dari budaya mereka, di mana mereka memiliki kontribusi signifikan dalam berbagai aspek kehidupan. Penelitian ini mengkaji bagaimana nilai-nilai budaya Bugis memfasilitasi kesetaraan gender dan pengaruhnya terhadap perempuan Bugis di zaman sekarang. Melalui studi kasus tentang lima perempuan Bugis di Makassar, penelitian ini mengidentifikasi tantangan serta peluang yang dihadapi perempuan dalam pengembangan diri dan partisipasi dalam masyarakat. Hasil penelitian menunjukkan bahwa sistem kekerabatan bilateral dalam budaya Bugis, yang memberi penekanan pada kedua garis keturunan ibu dan ayah, turut berperan dalam kemandirian ekonomi dan sosial perempuan Bugis. Keterlibatan aktif perempuan Bugis dalam bidang sosial, politik, dan ekonomi mencerminkan implementasi praktik kesetaraan gender. Penelitian ini memberikan pemahaman baru tentang dinamika kesetaraan gender dalam budaya Bugis serta dampaknya terhadap pemberdayaan perempuan Bugis pada masa sekarang. Pada akhirnya, penelitian ini menyoroti pentingnya menjaga nilai-nilai budaya yang mendukung kesetaraan gender sebagai dasar bagi pembangunan sosial dan ekonomi yang inklusif.This research aims to explore the impact of gender equality on the independence and power of Bugis women today. The role of women in Bugis society has long been an important part of their culture, where they have made significant contributions in various aspects of life. This research examines how Bugis cultural values facilitate gender equality and its impact on Bugis women today. Through case studies of five Bugis women in Makassar, it identifies the challenges and opportunities women face in their self-development and participation in society. The results show that the bilateral kinship system in Bugis culture, which emphasizes both maternal and paternal lineages, contributes to Bugis women's economic and social independence. Bugis women's active involvement in social, political and economic spheres reflects the implementation of gender equality practices. This research provides new insights into the dynamics of gender equality in Bugis culture and its impact on the empowerment of Bugis women today. Finally, it highlights the importance of maintaining cultural values that support gender equality as the basis for inclusive social and economic development.
PERAN AJARAN ISLAM BAGI PERKEMBANGAN KESULTANAN MALAKA DI JALUR MARITIM GLOBAL (1424 – 1511 M)
Authors: Anawagis Fian , Hijjang Pawennari , Yahya Yahya , Inawati Inawati
Published: July 2024

Penelitian ini bertujuan untuk bisa melihat kondisi sosial pada saat Kerajaan Malaka (i) Perkembangan kesultanan Malaka (ii) dan Pengaruh agama Islam kegiatan pelayaran dan perdagangan di Kesultanan Malaka (iii) Hasil penelitian menunjukkan bahwa (i) kondisi sosial kerajaan Malaka dipengaruhi oleh faktor letak, keadaan alam, dan lingkungan wilayahnya. Sebagai masyarakat yang hidup di daerah maritim, hubungan masyarakat sangatlah kurang dan bahkan cenderung ke sifat individualisme. (ii) setelah menerima Islam membuat kerajaan ini menjadi kesultanan Malaka yang dapat cepat berkembang, bahkan mengambil alih dominasi pelayaran dan perdagangan kerajaan Samudera Pasai yang kalah dalam bersaing. (iii) dengan masuknya pengaruh Islam, maka pelayaran dan perdagangan di Malaka mengalami kejayaan. Kejayaan Malaka disebabkan karena adanya peran kuat dan corak semangat Islam dalam undang-undang Malaka yang mengatur pelayaran dan perdagangan.This research aims to be able to see the social conditions during the Malacca Kingdom (i) The development of the Malacca Sultanate (ii) and the influence of Islam on shipping and trade activities in the Malacca Sultanate (iii) The results of the research show that (i) the social conditions of the Malacca Kingdom were influenced by location factors. , natural conditions and regional environment. As a society that lives in a maritime area, community relations are very lacking and even tend towards individualism. (ii) after accepting Islam, this kingdom became the sultanate of Malacca which was able to develop quickly, even taking over the dominance of shipping and trade from the Samudera Pasai kingdom which was losing in competition. (iii) with the arrival of Islamic influence, shipping and trade in Malacca experienced prosperity. Malacca's success was due to the strong role and spirit of Islam in Malacca's laws governing shipping and trade.
Strategi Pengolahan Buah Unggulan Menuju Pasar Ekspor dengan Pendekatan Manajemen Rantai Nilai Terintegrasi
Authors: Latif Dini Verdania , Abbas Sa'adah
Published: July 2024

Kementerian BUMN Republik Indonesia telah mencanangkan Revolusi Oranye sejak 17 Mei 2013. Gerakan nasional ini memiliki visi untuk terciptanya pemenuhan kebutuhan konsumsi buah nasional yang tidak bergantung pada impor dan dapat menjadikan Indonesia sebagai produsen dan eksportir buah-buahan tropis. Visi tersebut sebaiknya didukung oleh berbagai pihak, terutama petani buah yang merupakan ujung tombak program. Beberapa penelitian menunjukkan bahwa produktivitas petani buah di Indonesia masih rendah. Petani masih bertani secara yang tradisional dengan pertanian berskala kecil dan belum memahami pengelolaan hasil panen, sehingga produk tidak dapat berkelanjutan tersedia sepanjang tahun. Petani juga belum dapat memasarkan produknya sendiri. Penelitian ini bertujuan untuk menciptakan strategi baru untuk mengatasi permasalahan tersebut, yang dinamakan Rantai Nilai Terintegrasi. Strategi ini adalah strategi bisnis yang terintegrasi mulai dari pemasok, layanan, dan informasi yang dapat memberikan nilai tambah bagi pelanggan dan pemangku kepentingan lainnya. Produsen, yaitu petani tidak hanya bekerja sendiri tetapi perlu mendapat bantuan dari pihak lain, seperti para akademisi dan mahasiswa melalui kurikulum kampus merdeka, para penyuluh pertanian, perusahaan-perusahaan yang terkait, eksportir, bank, dan pihak lainnya. Strategi ini diharapkan dapat meningkatkan produktivitas petani dan menyukseskan Program Revolusi Oranye.
Pelatihan AI Based Education untuk Pemberdayaan Guru SMAN 1 Kabupaten Blora
Authors: Silitonga Lusia Maryani , Suciati Sri
Published: July 2024

Dalam era digital yang berkembang pesat, integrasi Kecerdasan Buatan (Artificial Intelligence/AI) dalam pendidikan menjadi sangat penting. SMA Negeri 1 Blora telah memelopori program pelatihan Pendidikan Berbasis AI yang bertujuan untuk memberdayakan guru dengan keterampilan dan literasi AI yang diperlukan untuk mendorong metodologi pengajaran yang inovatif. Program ini, yang secara strategis didukung oleh infrastruktur sekolah yang kuat, bertujuan meningkatkan pengalaman pendidikan melalui adopsi alat teknologi baru dan kurikulum integratif. Meskipun terdapat tantangan dalam adopsi teknologi karena beragamnya tingkat kesiapan di antara pendidik, program ini telah menunjukkan kemajuan substansial dalam meningkatkan penerimaan dan aplikasi teknik pembelajaran berbasis AI oleh guru. Inisiatif ini tidak hanya meningkatkan kualitas pendidikan di SMA Negeri 1 Blora tetapi juga berkontribusi pada pengembangan masyarakat dengan menyediakan akses ke pendidikan berkualitas tinggi yang canggih secara teknologi. Keberhasilan berkelanjutan dari program ini didukung oleh pelatihan berkelanjutan, pengembangan komunitas belajar, dan bimbingan terus menerus, memastikan adaptabilitas jangka panjang terhadap inovasi pendidikan.
Penerapan Project-Based Learning dan Video Youtube Pembelajaran Menulis Teks Prosedur Kelas Vll SMPN 2 Banjarharjo Brebes
Authors: Istiani Dea , Asrofah  , Anshori Kurniawan Latif
Published: July 2024

Penelitian ini bertujuan untuk mendeskripsikan penerapan project-based learning dan video YouTube dalam pembelajaran menulis teks prosedur kelas Vll SMPN 2 Banjarharjo Brebes Tahun Ajaran 2023/2024. Penelitian ini menggunakan metode campuran. Pengumpulan data yang digunakan dengan teknik tes dan nontes berupa observasi, wawancara, dan angket. Analisis data yang digunakan menggunakan triangulasi. Penyajian hasil analisis data dilakukan secara formal dan informal. Berdasarkan hasil penerapan tersebut menunjukan bahwa pembelajaran project-based learning dan video YouTube dapat diterapkan pada peserta didik kelas Vll SMPN 2 Banjarharjo tahun ajaran 2023/2024. Hal ini dapat didukung dengan peningkatan hasil rata-rata pretest 66, 21 meningkat menjadi 80,81. Selain itu hasil wawancara dapat meningkatkan semangat belajar peserta didik dan memudahkan dalam membuat teks prosedur yang baik dan benar sehingga pembelajaran di kelas lebih kondusif.
Waste management improvement with software application at Wringinsongo Village, Tumpang Regency, Malang
Authors: Wibowo Dimas Wahyu , Khairy Muhammad Shulhan , Rizza Muhammad Akhlis , Fitriana Annisa , Sari Padma Adriana
Published: July 2024

Wringinsongo Village, Tumpang Subdistrict, Malang Regency maintains a clean environment through environmentally friendly waste management. One of Wringinsongo's BUMDes (Village-Owned Enterprises) is the Waste Bank, which uses waste as a potential sector. It needs to get special attention related to its governance because the recording is still less effective and there are often calculation errors caused by the recording system using paper. Based on these conditions, it is necessary to develop an application to help record transaction activities at the Waste Bank. The Wringinsongo Village Waste Bank application can be accessed on both the web platform and Android mobile devices, based on the ease of access to the system by village managers and officials. After developing the application, socialization, and training were conducted to the Waste Bank manager and village officials to provide information on how to use the application. After three months of use, feedback was taken to get responses related to the use of the application. The result is that BUMDes managers find it easy to record and obtain accurate and faster calculation results.
Assistance in preparing financial reports for digital-based MSME actors in Tungkal Ilir Sub-District
Authors: Putri Utami Mizani , Khairiyani Khairiyani , Kurniyati Kurniyati , Wulandari Chintia Putri
Published: July 2024

Having good and correct financial reports using the Financial Accounting Standards for Micro, Small, and Medium Entities for MSMEs makes a benchmark for representing how the ongoing business performance is so that it can determine the future direction of the business smoothly The method used in this Community Service Activity (CSA) is Participatory Action Research (PAR). There are three main pillars of the PAR method, starting from the research methodology, the action dimension, and finally the participation dimension. The evaluation results of the implementation of activities for two days showed that the participants were very enthusiastic about making and preparing financial reports by utilizing the menu in the MSME Business Financial Records Application (Toko Ku). Participants can also utilize the report menu which consists of sales reports, expense reports, profit/loss reports, and general reports. These reports are outputs from menus such as cash, products, inventory, sales, receivables, payables, and expenses.
Hybrid project learning and peer teaching as learning strategies for learners with high activity
Authors: Mahfud Fakhris Khusnu Reza , Abidin Zainal , Nurhasan Usman
Published: July 2024

The mosque is the Muslim community's place of worship and education. Regular worship occurs according to a timetable. However, educational activities require quite a long time, so the mosque management schedules learning activities periodically. In addition, mosque congregations have a very high diversity and density of activities, especially mosque congregations in urban areas. The management of urban mosques has difficulty organizing learning consistently because the congregation has difficulty meeting at the same time periodically. This paper offers a solution by teaching with a hybrid learning method between project learning and peer teaching. Projects are created based on the needs of the environment and the congregation. The project development team is formed from worshipers who can work on projects. Other congregants receive knowledge through the project development team when the project is in the process of being created and run. This hybrid learning was experimented with by creating an aquaponics project. Aquaponics is operated with solar electricity. The project development team consists of a congregation of children to parents. The project has successfully transferred knowledge to the project development team members. The project operation attracts non-team worshippers to discuss independently with team members. Some non-team members have developed fish farming independently.
Education and nutrition intervention to mitigate stunting in Cisaranten Wetan, Cinambo District, Bandung
Authors: Astriany Dewi , Firmansyah Adang , Ismayadi Pupung , Risfayanti Iffa , Mutaqin Rizki Amaludin , Fitriansyah Sani Nurlaela
Published: July 2024

Stunting is a complex problem related to environmental health and the provision of nutritious food. Chronic malnutrition in children results in permanently impaired physical and cognitive growth. Cisaranten Wetan Village, Cinambo District, Bandung has problems with the health conditions of children who are indicated to be stunted. The purpose of this service activity is to provide education to Integrated Healthcare Center (in Indonesia: Posyandu) cadres and the community regarding stunting, as well as assistance with specific nutritional interventions for children indicated as stunted. Education was conducted by the STFI Community Service Team with the theme of balanced nutrition and child development in the form of counseling, videos, and leaflets. Children who are indicated to be stunted are given additional food in the form of egg powder, curcumin honey, and goat milk regularly. The existence of routine education carried out with various media causes a change in the level of knowledge from the moderate category to good in mother respondents with children who are indicated to be stunted. Increased maternal knowledge affects behaviour in parenting and child growth and development.
Preschool Educators’ Perspectives on Dialogic Literacy in Preschoolers
Authors: Papadopoulos I.
Published: July 2024

This research delves into the perceptions and expressions of dialogic literacy among preschool teachers, seeking to explore dimensions such as its definition, significance, strategies, assessment methods, and parental involvement. The study engaged a cohort of 15 educators, comprising 10 females and 5 males, selected based on their experience and qualifications in early childhood education. Through semi-structured interviews, these teachers provided rich and detailed insights, forming the basis for a thorough examination of dialogic literacy in the preschool setting. Intentionally diverse, the participant pool included educators from various preschool environments, both public and private, aiming to capture a broad spectrum of perspectives and approaches. This deliberate variation facilitated the exploration of potential disparities in understanding and implementing dialogic literacy across different contexts. Employing a qualitative research approach, the study emphasized semi-structured interviews as the primary method of data collection. The interview questions covered key aspects, including definitions, teacher strategies, classroom activities, assessment methods, and parental engagement. The design aimed to extract comprehensive responses, allowing participants to share their unique perspectives, experiences, and practices related to communicative proficiency in early childhood education. Thematic analysis was applied to categorize and organize the interview data, unveiling common patterns and themes. To enhance the study's reliability, methodologies such as member checking, peer debriefing, and triangulation were employed. The research maintained a strong ethical foundation, prioritizing participant privacy, confidentiality, and voluntary involvement throughout the entire process. The findings present a holistic understanding of dialogic literacy implementation in diverse preschool settings, enriched by the inclusion of educators with a minimum of two years of teaching experience. This study contributes valuable insights to the field of early childhood education, shedding light on the multifaceted nature of dialogic literacy and its versatile application across different educational contexts.
Reduction of Setup Times in a Metal Fabrication Company Using a Lean-Sigma Approach
Authors: Celis-Gracia Omar , García-Alcaraz Jorge Luis , Estrada-Orantes Francisco Javier , Avelar-Sosa Liliana , Alba-Baena Noe Gaudencio , Hermosillo-Villalobos Fabiola
Published: July 2024

Manufacturing companies face demand fluctuations and must deliver the required quantity of parts to their customers within the required time; however, companies face different challenges in fulfilling them. One is technological advances, which make it impossible for them to compete with other countries, such as China, due to financial issues. Therefore, manufacturing companies use continuous improvement methodologies to achieve better performance in their processes. Six Sigma and Lean Manufacturing are some of the best-known approaches. This article briefly presents the application of a lean sigma approach oriented to solving problems. This research proposes a methodology based on Lean Sigma that contrasts what different authors currently do: continuous improvement projects that take up to 12 months to produce results and do not solve a problem. This implementation is conducted in a process that manufactures metal parts and fails to deliver them on time to its customers. Using tools such as the Single Minute Exchange of Die (SMED) in a production line, on-time deliveries were increased from 89 % to 96 %; at the same time, the model change times were reduced by approximately 60 %, which is required for the implementation of this methodology for only four weeks, unlike the traditional six-sigma approach that can take up to 12 months to improve the process.
Thiamethoxam Residuality in Papaya Plant and Fruit (Carica papaya Linnaeus) Cultivated in Rotation with Watermelon (Citrullus lanatus)
Authors: Megchun Garcia Juan Valente , Castañeda Chávez María del Refugio , Rodríguez Lagunes Daniel Arturo , Lango-Reynoso Fabiola , Amaro-Espejo Isabel Araceli
Published: July 2024

There is evidence of the high use of the neonicotinoid insecticide thiamethoxam, in tropical crops, for its effectiveness in the control of soil and plant pests. The objective of this study was to know the residuality and concentration of thiamethoxam in the papaya agroecosystem, in the main papaya fruit producing zone in the central area of the Gulf of Mexico. It was carried out during a papaya growing cycle with watermelon rotation; the taking of samples was according to the technique established by the NOM -AA-103-1988 for leaves and for fruit the NMX -FF-041- 1996 by the method of quartering in papaya and watermelon, the samples were analyzed with a HPLC-UV, the data obtained were statistically analyzed by parametric and non-parametric Kruskal- Wallis tests. The presence of thiamethoxam was found in papaya and watermelon cultivation plants, the concentrations in papaya leaves reported a maximum value of 0.29 mg/kg, while for the leaves of the watermelon rotation fruit it was 0.15 mg/kg. In papaya fruit, thiamethoxam concentrations are within a range of 0.24 to 0.32 mg/kg. The concentrations and residuality of thiamethoxam mainly exceed the maximum tolerance and residuality limits of the EFSA and FAO.
The Stock Market in Capitalism
Authors: NARANJO NAVAS Christian Paúl , NAVAS LABANDA Alegría Cumandá
Published: July 2024

The essay performs a theoretical and historical review of the foundations of capitalism, the stock market, and its functionality in capitalism, seen within the context of business development, economic development, and international economic crises. Through a bibliographic, historical-analytical and descriptive review, we have reached the conclusion that, despite the risks that may come from flexible limits on stock exchanges, as in the cases of the Great Depression of 1929 or in the Great Recession of 2008, the benefits of the existence of an stock market are greater because they it helps to generate increases in savings, capital investments, job creation and, in general, in the well-being of society. This role of the stock exchanges allows capitalism to strengthen and evolve over time.
Femicidio y violencia de género en Ecuador: Hallazgos claves y tendencias emergentes
Authors: Molina-Panchi Pablo Alexander , Ramírez-Blacio Anita Maribel , Molina-Panchi Diego Fabián , Campaña-Chaglla Jimena Alexandra , Ponce-Andrade Ana Lucia
Published: July 2024

El femicidio es un problema social grave que persiste desde tiempos ancestrales y, lamentablemente, sigue dándose en nuestra realidad contemporánea. Tomando en cuenta esto, el objetivo del presente estudio es diagnosticar el comportamiento histórico de los casos de femicidio y su relación con las denuncias presentadas por violencia de género. Asimismo, la investigación tiene un enfoque cuantitativo, el cual está caracterizado por la utilización de pruebas estadísticas como: Kolmogórov-Smirnov, Correlación de Tau-b de Kendall y los modelos Arima de Box-Jenkins para analizar series temporales. Por otra parte, el diseño es no-experimental y longitudinal, y examina varios períodos de tiempo desde el año 2014 hasta 2022. Además, es un estudio explicativo-correlacional, que busca establecer la relación entre el femicidio y sus variables explicativas. Los principales resultados son: (i) la serie temporal de femicidios no sigue una distribución normal; (ii) el femicidio presenta estacionalidad en fechas especiales; (iii) un porcentaje significativo de víctimas dependía económicamente de sus parejas; (iv) se observa una alta concentración de casos en zonas urbanas; y, (v) ciertos tipos de denuncias contribuyen a mitigar esta problemática. En conclusión, se trata de una investigación que examina la evolución del femicidio y su vínculo con las denuncias por violencia de género, lo cual aporta resultados relevantes para el diseño de políticas públicas, en materia de prevención y erradicación de todo tipo de violencia de género contra las mujeres.
Desigualdad de género y su impacto en la sociedad ecuatoriana: Reflexiones y desafíos
Authors: Delgado Cevallos Daniela , Tapia José David
Published: July 2024

Los roles de género son construcciones sociales basadas en expectativas culturales sobre cómo hombres y mujeres deberían actuar y comportarse en la sociedad. Estos roles no sólo impactan la vida diaria de las personas, sino que también tienen un efecto en las relaciones familiares. Los roles tradicionales de género han influido en la vida familiar y la resolución de conflictos. El objetivo de esta revisión crítica es examinar la desigualdad de género y su impacto en la sociedad ecuatoriana, examinando investigaciones previas para comprender cómo estas expectativas sociales impactan en las tensiones y dificultades de la sociedad. A través de este análisis, pretendemos identificar patrones compartidos, áreas de preocupación y posibles soluciones para abordar y mitigar su impacto.
En la presente investigación se ha identificado que, la desigualdad de género persiste, afectando el acceso de las mujeres a derechos básicos. A pesar de sentencias y estándares internacionales, la legislación no se ha reformado, mostrando poco interés legislativo en abordar el problema. Se requiere una visión plural de la familia y la eliminación de prejuicios para promover derechos equitativos. La investigación en ciencias sociales es clave. Alcanzar la igualdad implica desafiar prejuicios, replantear la cultura y limitar el poder de instituciones sociales. La educación es fundamental en este proceso. Los roles de género perpetúan desigualdades y violencia, limitando los derechos de familias diversas. Es esencial reflexionar sobre las violencias sociales y despojarse de dogmatismos para avanzar hacia la justicia social.