bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Two Web-Based Interventions (Res-Up! and REMOTION) in Routine Outpatient Psychotherapy (Therapy Online Plus—TOP): Protocol for a Randomized Controlled Trial
Authors: Trimpop Leonie Franziska , Bielinski Laura Luisa , Berger Thomas , Willutzki Ulrike
Published: January 2023

Background

Only 11%-40% of those with a mental disorder in Germany receive treatment. In many cases, face-to-face psychotherapy is not available because of limited resources, such as an insufficient number of therapists in the area. New approaches to improve the German health care system are needed to counter chronification. Web-based interventions have been shown to be effective as stand-alone and add-on treatments to routine practice. Interventions designed for a wide range of mental disorders such as transdiagnostic interventions are needed to make treatment for mental disorders more accessible and thus shorten waiting times and mitigate the chronification of mental health problems. In general, interventions can be differentiated as having either a capitalization (CAP) focus—thus drawing on already existing strengths—or a compensation (COMP) focus—trying to compensate for deficits. Up to now, the effectiveness of transdiagnostic web-based interventions with either a CAP or a COMP focus has not yet been evaluated.

Objective

This study is the first to examine the effectiveness of two transdiagnostic web-based interventions: (1) the activation of resilience and drawing on existing strengths (CAP: Res-Up!) and (2) the improvement of emotion regulation (COMP: REMOTION), compared with care as usual (CAU) in routine outpatient psychotherapy.

Methods

Adults with at least 1 mental health disorder will be recruited at 4 outpatient centers in Germany. Participants will then be randomized equally into 1 of the 2 intervention groups Res-Up! (CAP) and REMOTION (COMP) or into the control group (CAU). Assessments will be made at baseline (T0), at 6 weeks after treatment start (T1), and at 12 weeks after treatment start (T2). A primary outcome will be symptom severity (Brief Symptom Inventory-18). Secondary outcomes will focus on emotion regulation and resilience.

Results

Participant recruitment and data collection started in April 2020 and were ongoing as of July 2022. We expect participants to benefit more from the interventions than from the CAU control on the dimensions of symptom severity, resilience, and emotion regulation. Furthermore, we expect to find possible differences between CAP and COMP. The results of the study are expected in 2023.

Conclusions

This randomized controlled trial will compare CAU with the transdiagnostic web-based interventions Res-Up! and REMOTION, and will thus inform future studies concerning the effectiveness of transdiagnostic web-based interventions in routine outpatient psychotherapy.

Trial Registration

ClinicalTrials.gov NCT04352010; https://clinicaltrials.gov/ct2/show/NCT04352010

International Registered Report Identifier (IRRID)

DERR1-10.2196/41413
The Use of Social Media by Clinical Nurse Specialists at a Tertiary Hospital: Mixed Methods Study (Preprint)
Authors: AL-Rumhi Alya , AL-Rasbi Samira , Momani Aaliyah M
Published: January 2023

BACKGROUND

Recently, many health care professionals, who use social media to communicate with patients and colleagues, share information about medical research and promote public health campaigns.

OBJECTIVE

This study aimed to examine the motives, barriers, and implementation of social media use among clinical nurse specialists in Oman.

METHODS

A mixed methods study was conducted among 47 clinical nurse specialists at Sultan Qaboos University Hospital between November and December 2020. Qualitative data were collected using an open-ended questionnaire and analyzed using thematic analysis, and quantitative data were collected with a questionnaire and analyzed using SPSS (version 21.0; IBM Corp).

RESULTS

Of the 47 clinical nurse specialists surveyed, 43 (91.5%) responded. All respondents reported using social media applications, with WhatsApp being the most commonly used platform. Most respondents (n=18, 41.9%) spent 1-2 hours per day on social media. The main motives for using social media were increasing knowledge, communication, reaching patients easily, and reducing the number of hospital visits. The main barriers to social media use were privacy concerns, time constraints, and a lack of awareness of legal guidelines for social media use in the workplace. All participants requested clear rules and regulations regarding the use of social media among health care providers in the future.

CONCLUSIONS

Social media has the option to be a powerful institutional communication and health education tool for clinical nurse specialists in Oman. However, several obstacles must be addressed, including privacy concerns and the need for clear guidelines on social media use in the workplace. Our findings suggest that health care institutions and clinical nurse specialists must work together to overcome these impediments and leverage the benefits of social media for health care.Bottom of Form
Mobile Assessments of Mood, Cognition, Smartphone-Based Sensor Activity, and Variability in Craving and Substance Use in Patients With Substance Use Disorders in Norway: Prospective Observational Feasibility Study (Preprint)
Authors: Lauvsnes Anders Dahlen Forsmo , Hansen Tor Ivar , Ankill Sebastian Øiungen , Bae Sang Won , Gråwe Rolf W , Braund Taylor A , Larsen Mark , Langaas Mette
Published: January 2023

BACKGROUND

Patients with substance use disorders (SUDs) are at increased risk for symptom deterioration following treatment, with up to 60% resuming substance use within the first year posttreatment. Substance use craving together with cognitive and mental health variables play important roles in the understanding of the trajectories from abstinence to substance use.

OBJECTIVE

This prospective observational feasibility study aims to improve our understanding of specific profiles of variables explaining SUD symptom deterioration, in particular, how individual variability in mental health, cognitive functioning, and smartphone use is associated with craving and substance use in a young adult clinical population.

METHODS

In this pilot study, 26 patients with SUDs were included at about 2 weeks prior to discharge from inpatient SUD treatment from 3 different treatment facilities in Norway. Patients underwent baseline neuropsychological and mental health assessments; they were equipped with smartwatches and they downloaded an app for mobile sensor data collection in their smartphones. Every 2 days for up to 8 weeks, the patients were administered mobile ecological momentary assessments (EMAs) to evaluate substance use, craving, mental health, cognition, and a mobile Go/NoGo performance task. Repeated EMAs as well as the smartphone’s battery use data were averaged across all days per individual and used as candidate input variables together with the baseline measures in models of craving intensity and the occurrence of any substance use episodes.

RESULTS

A total of 455 momentary assessments were completed out of a potential maximum of 728 assessments. Using EMA and baseline data as candidate input variables and craving and substance use as responses, model selection identified mean craving intensity as the most important predictor of having one or more substance use episodes and with variabilities in self-reported impulsivity, mental health, and battery use as significant explanatory variables of craving intensity.

CONCLUSIONS

This prospective observational feasibility study adds novelty by collecting high-intensity data for a considerable period of time, including mental health data, mobile cognitive assessments, and mobile sensor data. Our study also contributes to our knowledge about a clinical population with the most severe SUD presentations in a vulnerable period during and after discharge from inpatient treatment. We confirmed the importance of variability in cognitive function and mood in explaining variability in craving and that smartphone usage may possibly add to this understanding. Further, we found that craving intensity is an important explanatory variable in understanding substance use episodes.

CLINICALTRIAL
User Evaluation of a Chat-Based Instant Messaging Support Health Education Program for Patients With Chronic Kidney Disease: Preliminary Findings of a Formative Study (Preprint)
Authors: Chen Nai-Jung , Huang Chiu-Mieh , Fan Ching-Chih , Lu Li-Ting , Lin Fen-He , Liao Jung-Yu , Guo Jong-Long
Published: January 2023

BACKGROUND

Artificial intelligence–driven chatbots are increasingly being used in health care, but few chat-based instant messaging support health education programs are designed for patients with chronic kidney disease (CKD) to evaluate their effectiveness. In addition, limited research exists on the usage of chat-based programs among patients with CKD, particularly those that integrate a chatbot aimed at enhancing the communication ability and disease-specific knowledge of patients.

OBJECTIVE

The objective of this formative study is to gather the data necessary to develop an intervention program of chat-based instant messaging support health education for patients with CKD. Participants’ user experiences will form the basis for program design improvements.

METHODS

Data were collected from April to November 2020 using a structured questionnaire. A pre-post design was used, and a total of 60 patients consented to join the 3-month program. Among them, 55 successfully completed the study measurements. The System Usability Scale was used for participant evaluations of the usability of the chat-based program.

RESULTS

Paired t tests revealed significant differences before and after intervention for communicative literacy (t54=3.99; P<.001) and CKD-specific disease knowledge (t54=7.54; P<.001). Within disease knowledge, significant differences were observed in the aspects of CKD basic knowledge (t54=3.46; P=.001), lifestyle (t54=3.83; P=.001), dietary intake (t54=5.51; P<.001), and medication (t54=4.17; P=.001). However, no significant difference was found in the aspect of disease prevention. Subgroup analysis revealed that while the findings among male participants were similar to those of the main sample, this was not the case among female participants.

CONCLUSIONS

The findings reveal that a chat-based instant messaging support health education program may be effective for middle-aged and older patients with CKD. The use of a chat-based program with multiple promoting approaches is promising, and users’ evaluation is satisfactory.

CLINICALTRIAL

ClinicalTrials.gov NCT05665517; https://clinicaltrials.gov/study/NCT05665517
Attitudes and (Mis)information About Cognitive Behavioral Therapy on TikTok: An Analysis of Video Content (Preprint)
Authors: Lorenzo-Luaces Lorenzo , Dierckman Clare , Adams Sydney
Published: January 2023

UNSTRUCTURED

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Longitudinal insights in psychosocial stress expressed by health care professionals during the COVID-19 pandemic – a mixed-method approach (Preprint)
Authors: Hummel Svenja , Michelsen Ina , Zafar Ali , Moritz Steffen , Benoy Charles , Lemogne Cedric , Resende de Almeida Rosa Maria , Losada Durán Raquel , Oscar Ribeiro , Frisardi Vincenza , Tarricone Ilaria , Ferrari Silvia , Dechent Frieder , Christian Huber , Weidt Steffi , Mayer Gwendolyn , Schultz Jobst-Hendrik
Published: January 2023

BACKGROUND

COVID-19 has affected everyday life and working conditions for most European people, particularly health care professionals (HCP). The worsening of mental health, work-related stressors, and helpful coping strategies within HCP have been studied by various quantitative surveys for all waves of infection. Longitudinal comparisons of stressors and coping as well as the themes that are particularly stressful for the HCP on different levels of experience at distinct timepoints of the pandemic are missing.

OBJECTIVE

Analyzing stressors, coping strategies, and underlying psychosocial stress factors and unmet needs expressed by HCP and non-medical staff at the beginning of the COVID-19 pandemic and the third wave of infections in different European countries.

METHODS

A cross-sectional survey was conducted in two study periods during COVID-19 pandemic in different European countries. The first study period was between April 1st and June 20th 2020 and the second between the November 25th 2021 and February 28th 2022. Quantitative descriptive analysis was conducted for questionnaires on stressors and coping strategies. Thematic analysis was used to complement the quantitative data with the results of the qualitative data to explore further levels of experience of the individual.

RESULTS

The most severe stressors identified at both timepoints were the uncertainty about when the pandemic will be under control and the fear of infecting the family. Commonly used coping strategies were the use of protective measures and the collection of information on COVID-19. A thematic analysis revealed 8 first level themes (pandemic situation, government/politics, social climate, measures, working conditions, infection effects, daily life, coping) which can be seen as levels of experience. During the beginning of the pandemic, comments focused on needs regarding protective equipment and handling the social-distancing situation, while unmet psychosocial needs came up only in the second study period.

CONCLUSIONS

Over the course of three years of the pandemic, there is still a need in the psychosocial pandemic preparedness of health care professionals that deserves further research and coverage. Despite many government and work-related measures, a deterioration of mental health in HCP, could be observed. It is important for future crises to cover the gaps in psychosocial support needs revealed by the COVID-19 pandemic. Thus, an improvement in pandemic preparedness and a mentally healthier population must be ensured in the future.
Consumo energético y emisiones de GEI en Alta Velocidad Ferroviaria, caso Guadalajara-Ciudad de México- Veracruz
Authors: Guerrero Fernández José Antonio , Obregón-Biosca Saúl Antonio
Published: January 2023

La emisión de gases de efecto invernadero y su relación con el consumo energético están ligados al sector transporte. La presente investigación aborda la relevancia de este fenómeno en los proyectos ferroviarios de alta velocidad al considerar las fuentes originarias de electricidad. Se usaron, como casos de estudio, dos corredores de transporte con alta demanda en México: el primero Ciudad de México-Guadalajara y, el segundo, Ciudad de México-Puerto de Veracruz. Al incluir al tren de alta velocidad en estos corredores, el consumo energético disminuye, mientras la emisión de gases a la atmósfera aumenta.
Maíz de temporal: ¿es suficiente el conocimiento etnoecológico para afrontar la variabilidad climática?
Authors: Romero Contreras Alejandro Tonatiuh , Becerril-Piña Rocio , Díaz-Delgado Carlos , Mastachi-Loza Carlos Alberto , Vilchis-Francés Aleida , Arévalo-Mejía Ricardo
Published: January 2023

México es identificado como centro de origen del maíz; a ello se agrega un sólido conocimiento etnoecológico local sobre su cultivo, clima y cosmogonía. Esta investigación plantea: 1) integrar y capitalizar el conocimiento del campesino en la Cuenca Alta del Río Lerma y 2) identificar detonadores de sostenibilidad local. Mediante entrevistas etnoecológicas y el método Delphi se construyó un modelo conceptual del cultivo de maíz de temporal, basado en cuatro dimensiones: maíz, labores agrícolas, clima-ambiente y religión-cosmogonía. La variabilidad climática, el cambio generacional y la industrialización podrían ser un desafío para los campesinos si no se capitaliza su conocimiento etnoecológico.
The Effect of Influencer Marketing on Trust, Trust Tendency and Consumer Purchase Intention: Instagram Example
Authors: Durmaz Yakup , Cavus Omer , Wilk-Jakubowski Grzegorz
Published: January 2023

The purpose of this article is to analyze the impact of influencer marketing on trust, trust inclination and consumer purchasing intentions. In addition, this study aims to turn the negative perceptions of influencer marketing of companies into positive and raise awareness accordingly. SPSS 26 and Amos programs were used. In this study; Frequency, percentage, standard deviation, average, factor analysis, correlation and regression analysis were performed on the survey form data, which was easily distributed by sampling method and filled out completely by 411 Instagram users over the age of 18. Instagram influencer marketing has been found to have a positive and positive effect on confidence, confidence trend and consumer purchasing intentions. Not all Instagram users could be reached; The method used limits the general ability of the findings. However, the findings offer preliminary insights into future studies of influencer marketing. Companies will actively interact with customers using various social media platforms and influencers, and thus it is thought that they will succeed in marketing through social media.
La industria de la inteligencia artificial: una carrera por su liderazgo
Authors: Avaro Dante
Published: January 2023

La inteligencia artificial (IA) puede considerarse una industria, tal como se concibe a ésta en la teoría económica. En ese contexto se observan dos procesos simultáneos: concurrencia ycooperación. Es bajo este escenario que, entonces, conviene situar la actual disputa entre China y Estados Unidos por el liderazgo mundial en IA. Así, resulta de sumo interés en el presente trabajo describir políticas y medidas concretas, que el régimen chino siguió adelante no sólo para promover su industria de IA, sino también para identificar cuál es su estrategia para aumentar su influencia en los procesos de estandarización en la incipiente industria.
The Adsorption of Hydrogen in an Activated Carbon Tank Based on Modified Dubinin-Astakhov Model
Authors: Akhtar Farheen , Anand Rajneesh
Published: January 2023

Abstract: During adsorption cycles, the simulations of thermal effects play a significant role in designing adsorption-based systems such as gas separation, gas storage and heat pumps. This paper presents the two-dimensional axisymmetric model of a hydrogen storage tank on activated carbon at a particular temperature and pressure range using User Defined Functions in Fluent (UDF). The adsorption model used for CFD analysis is based on mass, momentum and energy equations and the modified form of Dubinin-Astakhov model. The simulation is implemented through Ansys Fluent. The Linear Driving Force is applied to study the cryo-adsorption kinetics. The results are varied from pipe inlet to the tank wall based on mass flux at different flow times. The pressure and temperature profile inside the system for different inlet conditions is studied in detail. The profiles of pressure and temperature are plotted at different time intervals. The velocity distribution at various time intervals is presented for charging and discharging of hydrogen adsorption Moreover, the results are compared with the model parameters of carbon and steel by varying the thermal conductivities and specific heat capacities. The results obtained for the pressure and temperature profile shows a good agreement with the other results available in the literature.
Analysis of the operation of a device for installing outriggers of self-propelled chassis of mobile transport and reloading rope complexes
Authors:   Academician I.G. Petrovskii Bryansk State University, Lagerev A.V. , Lagerev I.A. ,   Academician I.G. Petrovskii Bryansk State University
Published: January 2023

Single-span mobile ropeways of the pendulum type, formed with the help of two mobile transport and reloading rope complexes connected by a single rope system on the basis of self-propelled wheeled chassis of high cross-country ability and carrying capacity, are currently considered as a promising type of transporting equipment for solving many tasks in adverse natural and social situations. The article is devoted to an important technical task of ensuring the safe operation of rope complexes associated with the loss of overall stability and overturning of the wheeled chassis under conditions of significant operational loads from the tension of the rope system, creating an overturning moment. The original design of the device for the installation of outriggers is presented in detail, providing automated execution of the necessary technological work. The developed method of designing this device is based on the analysis of the kinematics of the movable structural elements of the device, which allowed us to establish the calculated dependencies for determining the main structural dimensions. The considered design and design methodology can be used in the creation of transport and technological machines of other functional purposes, during the operation of which situations of loss of overall stability and overturning are possible.
Productivity of cargo mobile ropeways based on coupled mobile transport and overloading rope complexes
Authors:   Academician I.G. Petrovskii Bryansk State University, Lagerev A.V. , Tarichko V.I. ,   Special Design Bureau of machine building, Lagerev I.A. ,   Academician I.G. Petrovskii Bryansk State University
Published: January 2023

Single-span mobile pendulum-type ropeways formed by two coupled self-propelled wheeled chassis of high load capacity and cross-country capability are a promising type of transport and reloading equipment under difficult operating conditions. This article discusses the problem of assessing the weight productivity of such mobile ropeways under various technological options and modes of their operation. A computational method for determining the productivity within the area of the possible use of mobile ropeways is presented, characterized by the magnitude of the span and the angle of inclination of the line of the carrying-traction rope between the terminal points of the route, as well as the weight of the transported cargo. It is shown that the weight productivity significantly depends on the duration of loading and reloading operations and therefore is a variable characteristic of a mobile ropeway, depending on the specific operating conditions (used lifting and rigging equipment, the qualifications of the service personnel, the weight and configuration of the transported cargo, the availability of storage sites, etc.).
Results of dynamic simulation of the lateral stability of a light van when curvilinear movement
Authors:   Kaluga Branch of Bauman Moscow State Technical University, Nikitin G.S. , Win T.N. ,   Kaluga Branch of Bauman Moscow State Technical University
Published: January 2023

The article presents the results of developing a methodology and implementing dynamic modeling in the SolidWorks Motion 2016 software environment for changing the body roll angle of the Gazelle Next van during active maneuvering and turning using a lever-electromagnetic stabilization system in comparison with a lever stabilizer system. A dynamic modeling technique was developed to analyze the change in the roll angle of the Gazelle NEXT all-metal van in the driving mode when turning and intensive maneuvering with a lever and using a lever-electromagnetic stabilization system). As a result of the research, a decrease in the roll angle of the Gazelle Next all-metal van was revealed in driving modes with active maneuvering and cornering using the lever-electromagnetic stabilization system relative to that installed on the example of the Gazelle NEXT — lever. The proposed method of dynamic modeling proved the effectiveness of using a lever-electromagnetic stabilization system when turning and active maneuvering, compared with standard lever stabilizers based on a comparison of the roll angles of the first and second options.
Development of an automated information system according to the assessment of the volume of accumulation of solid municipal waste
Authors:   Academician I.G. Petrovskii Bryansk State University, Lagerev I.A. , Perminova D.I. ,   Academician I.G. Petrovskii Bryansk State University
Published: January 2023

The article presents scientific approaches to assessing the volume of solid municipal waste accumulation in order to determine standards using a distributed information system. The description of the automated information system and algorithms of its use is given, taking into account the experience gained by specialists of the Academician I.G. Petrovskii Bryansk State University when performing work commissioned by the Department of Natural Resources and Ecology of the Bryansk Region (contract No. 02-22 dated 01.03.2022).
Legal Formulation to Overcome Base-Erosion and Profit-Shifting Practices of Digital-Economy Multinational Enterprise in Indonesia
Authors: Butarbutar Russel
Published: January 2023

This study discusses Indonesian legal strategies and formulations to handle tax avoidance originating from Base Erosion Profit Shifting (BEPS) carried out by the digital-economy multinational enterprise. It is a normative (doctrinal) study supported by non-doctrinal methods to reveal the truth based on the logic of legal scholarship. It also compared the practices to the tax provisions, legislation, and cases in India, the United Kingdom, Australia, and Malaysia. At least two theories underlie the study. The first is the legal theory of justice, certainty, and expediency from Gustav Radbruch. The second is the theory of international cooperation. The study found several points. First, multinational enterprise strategies avoid tax by means of Permanent Establishment techniques in low-tax jurisdictions, transfer pricing, and tax treaty shopping. Second, to tackle the multinational enterprise that conducts BEPS in the field of the digital economy, (1) all countries have developed and amended laws and regulations related to e-commerce taxation and the digital economy; and (2) all countries carry out international cooperation, both bilaterally and multilaterally through tax treaties, MLI, and CbC reporting.
Sociological analysis of the distributed team leadership
Authors: Zabolotskikh A. V. , Dugina T. V. , Ignatova T. A.
Published: January 2023

The importance of leadership in social and scientific spheres has been studied from different perspectives; the paradigms, approaches and methods have been constantly changing. The pattern of the authoritarian leader in the society has receded in favour of distributed leadership, and today researchers consider interpersonal relationships as the main factor of the leader’s effectiveness if he is capable of fostering leadership in others. Thus, in the team, the potential of leadership is distributed between those members who are capable and not afraid of taking responsibilities. Leaders who help to create the next generation of leaders are more valuable for the society than those who are concentrated on their personal ambitions. The authors consider the features of distributed leadership within one group in the course of time. The authors applied different methods to analyse distributed leadership - a survey and a participant observation - to study manifestations of distributed leadership in time and space, the relationship between distributed leadership in the group and context, the nature of the interaction of group agents in legitimisation and dominance, and the participation of group members in social interaction. The article examines the features of distributed leadership based on the study conducted at the RUDN University in 2017-2020 within one group. The results show that distributed leadership is effectively regarded in time and space: the leader takes a flagship role and relies on the acquired experience when interacting with other members of the group; it is possible for several leaders to co-exist under certain social conditions and in distributed areas.
Variabilitas Karakter Morfologi Pada Populasi Kelapa (Cocos nusifera L.) Di Kabupaten Tanjung Jabung Barat
Authors: Oktavia Yesi , Kartika Elis , Riduan Ahmad
Published: January 2023

Penelitian ini bertujuan untuk mendapatkan informasi tentang variabilitas karakter morfologi kelapa serta mendapatkan informasi tentang adanya korelasi antar karakter kuantitatif kelapa di Kabupaten Tanjung Jabung Barat. Penelitian dilaksanakan di 8 kecamatan yang terdapat di kabupaten Tanjung Jabung Barat provinsi Jambi, yaitu: kecamatan Batang Asam, kecamatan Renah Mendaluh, kecamatan Pengabuan, kecamatan Senyerang, kecamatan Tungkal Ilir, kecamatan Bram Itam, kecamatan Betara, dan kecamatan Kuala Betara. Penelitian dimulai bulan Agustus sampai dengan bulan September 2020, menggunakan metode deskriptif kuantitatif. Data diperoleh melalui survei dan wawancara terhadap petani pemilik tanaman kelapa. Teknik pengambilan sampel menggunakan proportional stratified random sampling yaitu teknik pengambilan sampel dengan memperhatikan strata atau tingkatan proporsi sampel yang diambil pada tanaman. Variabel yang diamati secara kualitatif dan kuantitatif yaitu warna buah, bentuk buah, bentuk cangkang, lingkar buah, panjang buah, jumlah buah per tandan, lingkar batang, berat buah, jumlah tandan buah, panjang tangkai tandan, panjang tangkai daun, dan panjang pelepah daun. Hasil penelitian menunjukkan adanya kriteria sangat sempit, luas, dan sangat luas yang ditemukan pada karakter yang diukur secara kualitatif dan kuantitatif. Karakter dengan kriteria sangat sempit yaitu warna buah, lingkar buah, panjang buah, lingkar batang, panjang tangkai tandan, panjang tangkai daun dan panjang pelepah daun. Karakter dengan kriteria luas dan sangat luas yaitu berat buah, bentuk buah, bentuk cangkang, jumlah buah, dan jumlah tandan. Sedangkan hasil analisis korelasi menunjukkan adanya korelasi antar karakter komponen hasil yaitu a) karakter panjang buah berkorelasi positif dengan lingkar buah, b) jumlah buah berkorelasi negatif dengan lingkar buah dan panjang buah, c) berat buah berkorelasi positif dengan lingkar buah dan panjang buah namun berkorelasi negatif dengan jumlah buah, d) jumlah tandan berkorelasi positif dengan jumlah buah, e) lingkar batang berkorelasi positif dengan panjang buah. Sedangkan korelasi yang bukan komponen hasil yaitu, f) panjang tangkai daun berkorelasi positif dengan lingkar batang, dan g) panjang pelepah daun berkorelasi positif dengan panjang tangkai daun.
Dampak Erosi Terhadap Kehilangan Hara Makro Pada Lahan Agroforestry Kopi Dan Kayu Manis Di Kecamatan Siulak Kabupaten Kerinci
Authors: Wahyu Pratama Zefa , Syarif M. , Junedi Heri
Published: January 2023

Kabupaten Kerinci terletak pada posisi 01°40’ dan 02°26’ Lintang Selatan, serta 101°08’ sampai

dengan 101°50’ Bujur Timur. Wilayah Provinsi Jambi sepenuhnya berada di selatan garis

2 khatulistiwa. Luas wilayah Kabupaten Kerinci adalah 332.814 Ha atau 3328,14 km . Tanah di

Kecamatan siulak memiliki unsur hara yang rendah serta pH berkisar (4,6-5,18). Kondisi tanah dengan unsur hara yang rendah dalam tanah yang mengakibatkan terhambatnya pertumbuhan tanaman. Penelitian ini bertujuan untuk mengetahui kehilangan hara makro akibat tererosi pada lahan agroforestry kopi dan kayu manis. Penelitian ini telah dilaksanakan di Kecamatan Siulak, Kabupaten Kerinci dengan metode pengukuran langsung di lapangan. Penentuan lokasi penelitian dilakukan secara purposive sampling. Metode analisis yang digunakan adalah metode C-organik (Kurmis), N Total (Kjeldhal), P-tersedia (Bray I), dan K-dd (NH4OAc pH 7.0 1N). Hasil Penelitian menunjukkan3 -1 erosidanaliranpermukaansertakehilanganharasebesaraliranpermukaan10,71m ha ,erosi0,987

3 -1 ton ha−1, pada lahan P1 lebih besar dari lahan P2 dengan aliran permukaan 1,32 m ha , erosi 0,011

-1 -1 -1 ton ha−1. Jumlah kehilangan, N 4,83 g l , P 0,82 g l , dan K 0,0723 g l , pada lahan P1 lebih tinggi

-1 -1 -1 darilahanP2dengan(N0,82gl ,P0,00042gl ,danK0,00240gl ).
Validating the TeenHITSS to Assess Child Abuse in Adolescent Populations
Authors: Day Philip G. , Woods Sarah B. , Gonzalez Leo , Fernandez-Criado Rodolfo , Shakil Amer
Published: January 2023

Purpose: The purpose of this study is to establish the psychometric properties and diagnostic accuracy of the Teen Hurt-Insult-Threaten-Scream-Sex (TeenHITSS), a 5-item measure used to screen adolescents for family violence in clinical settings.
Methods: Study participants included 251 adolescent participants (n=197 not at-risk subsample; n=56 at-risk subsample), recruited from ambulatory care clinics, a medical center at-risk referral clinic, and area shelters. Participants completed a cross-sectional survey, including the TeenHITSS and Parent-Child Conflict Tactics Scales (CTSPC) questionnaires. We calculated internal reliability, validity, and sensitivity and specificity for the full sample and both subsamples for each screening instrument.
Results: Concurrent validity between the TeenHITSS and CTSPC was strong (r=.71, P<.000). We determined an optimal cutpoint based on sensitivity and specificity for correctly identifying abuse victims as a score of one or greater on the TeenHITSS. The TeenHITSS also proved slightly superior to the CTSPC in differentiating between victims and nonvictims of adolescent abuse (AUC=.79 vs .73, respectively).
Conclusions: The TeenHITSS screening tool performed as well as the CTSPC in correctly classifying at-risk and not-at-risk teenagers and offers much greater utility to providers by supplying an actionable cut score. The findings of this study suggest that TeenHITSS is a valid and reliable tool to screen for physical and sexual abuse in children ages 13 years and older in clinical settings and can help health care providers detect adolescent abuse and initiate intervention and prevention of future abuse.
Multiplicative Kulli-Basava Indices
Authors: V.R.Kulli
Published: January 2023

A topological index is a numeric quantity from the graph structure of a molecule. In this paper, we introduce the multiplicative total Kulli-Basava index, multiplicative modified first Kulli-Basava index, multiplicative F-Kulli-Basava index, general multiplicative Kulli-Basava index of a graph. We compute these indices for regular graphs, wheel, gear and helm graphs.
Fuzzy γ-Baire Spaces and Fuzzy γ-D-Baire Spaces
Authors: Dipankar De
Published: January 2023

In this paper, we introduce the concept of fuzzy y-Baire space and fuzzy y-DBaire space. Some basic theorems and results of these spaces are introduced and also studied. Several examples are given to explain the concepts of these spaces.
The Modular Group of the form : M2n X C2
Authors: Adebisi S. A. , M. EniOluwafe
Published: January 2023

In this paper, the classification of finite p-groups is extended to the group of the modular structure m2n × c2, and the number of distinct subgroups were computed, making the classification of the given structure possible for the given prime p = 2
Some Operations on Complex Vague Graphs with Application
Authors: Kumar P.K Kishore , Manshath A.  , Rashmanlou Hossein , Taheri Morteza , Talebi Yahya , F. Mofidnakhaei
Published: January 2023

Vague graphs has found its importance in most recent years. It has played the vital role in many real life applications. The mathematical approach of blending different aspects of vague graphs gives a more generalized approach. As a result of it, we introduce the concepts of Complex vague graphs (CVG). In this chapter, we introduce certain notions including union, join, complement and composition of complex vague graphs. This helps in manipulating the real life applications in decision making problems. We also investigate on the ideas of homomorphisms of complex vague graphs. Finally we provide an application of CVG in launching a water reservoir in different locations.
A Fuzzy Inventory System of Inflation Effect and TimeRelated Demand
Authors: Hossen Mohammad Anwar
Published: January 2023

In this research work, a fuzzy inventory model was developed for deteriorating items with time-dependent demand considering the inflation effect. Shortages if any are allowed and partially backlogged with a variable rate dependent on the duration of waiting time up to the arrival of the next lot. The corresponding problem has been formulated as a nonlinearly constrained optimization problem, all the cost parameters are fuzzy valued and solved. Numerical examples have been considered to illustrate the model and the significant features of the results are discussed. Finally, based on these examples, sensitivity analyses have been studied by taking one parameter at a time keeping the other parameters as same.
An open-source tool for evaluating calibration techniques used in low-cost air pollutant monitors
Authors: Tatsch Daniel , Ramirez Alejandro , Campo Fernando , Hoinaski Leonardo , González-Dalmau Evelio
Published: January 2023

Low-cost air pollutant sensors suffer several interferences due to the variation of climatic elements. Recent studies look for calibration solutions based on different regression and classification machine learning algorithms. The present work brings together the implementation and extraction of performance metrics from these algorithms in a single open-source tool. Both the input data and parameters for each algorithm are automatically configured. This feature makes the tool compatible with any input dataset and removes the need to interact with complex codes.
An atypical presentation of hypothyroidism with proximal extremities weakness
Authors: Arezoumand Alireza , Nazari Sahar , Jazi Kimia , Riyah Mohammad Mehdi , Akbarimehr Melika , Masoumi Maryam
Published: January 2023

Myopathy-related symptoms are rare manifestations of hypothyroidism.
Clinicians should consider hypothyroid myopathy as one of possible
diagnosis for patients with proximal weaknesses. We report a 34-year-old
woman, presenting with a new atypical musculoskeletal manifestation of
hypothyroidism mimicking polymyositis.
Low-dose aspirin for preterm birth prevention in LMICs: a systematic review and meta-analysis.
Authors: Ganpat Yeeshana , Campbell Fiona
Published: January 2023

Background Low-dose aspirin (LDA) is recommended to improve birth
outcomes in high-risk pregnant women from developing countries. There is
no aggregate data from developing countries on LDA’s effect on preterm
births. Objective To systematically review and collate clinical data to
determine the effects of LDA on preterm births in women from low- and
middle-income countries (LMICs). Search strategy MEDLINE, Embase and
Cochrane CENTRAL databases were systematically searched in 2020.
Selection criteria Randomized Controlled Trials (RCTs) of LDA compared
with placebo or no treatment for preterm births in at-risk pregnant
women from LMICs. Data collection and analysis Two authors independently
screened the studies, extracted data and assessed quality. Pooled effect
sizes were calculated using random effects models. The Cochrane risk of
bias and Grading of Recommendations Assessment, Development and
Evaluation (GRADE) tools were used to assess the quality of studies and
overall quality of evidence. Main results Ten RCTs with 23 654
participants were included; studies were published between 1996 and
2020. Nine RCTs with 23 486 patients were pooled for the outcome preterm
birth. Meta-analysis results suggest significantly reduced risks of
preterm births (RR 0.90, 95% CI 0.82-0.98, p = 0.01) and perinatal
mortality (RR 0.83, 95% CI 0.73-0.94, p < 0.01) in the LDA
group. Conclusion Targeted LDA therapy should be considered to reduce
preterm births in at-risk pregnant women from LMICs. Funding This
research did not receive any specific grant from funding agencies in the
public, commercial, or not-for-profit sectors. Keywords Low-dose
aspirin, preterm birth, pre-eclampsia
Phenotypic plasticity: the role of a phosphatase family in the genetic regulation of Bacilli
Authors: Kovács Ákos T. , Gallegos-Monterrosa Ramses
Published: January 2023

In the last two decades, an increasing number of bacterial species have
been recognized that are able to generate a phenotypically diverse
population that shares an identical genotype. This ability is dependent
on a complex genetic regulatory network that includes cellular and
environmental signals, as well as stochastic elements. Among
Bacilli, a broadly distributed family of Rap (Response-regulator
aspartyl phosphate) phosphatases is known to modulate the function of
the main phenotypic heterogeneity regulators by controlling their
phosphorylation. Even more, their related extracellular Phr (Phosphatase
regulator) peptides function as quorum sensing signals, creating a
cell-cell communication network that regulates the phenotypic
development of the entire population. In this review, we examine the
role that the Rap phosphatases and their Phr peptides play in the
regulation of B. subtilis phenotypic differentiation, and in
other members of the Bacillus genus. We also highlight the
contribution of these regulatory elements to the fitness of bacterial
cells and mobile genetic elements, e.g. prophages and conjugative
vectors.
Cloning, Characterization, and Inhibition of the Novel β-Carbonic Anhydrase from Parasitic Blood Fluke, Schistosoma mansoni
Authors: Haapanen Susanna , Angeli Andrea , Tolvanen Martti , Emameh Reza Zolfaghari , Supuran Claudiu T. , Parkkila Seppo
Published: January 2023

Schistosoma mansoni is an intestinal parasite with one β-class
carbonic anhydrase, SmaBCA. We report the sequence enhancing,
production, catalytic activity, and inhibition results of the
recombinant SmaBCA. It showed significant catalytic activity on CO
hydration in vitro with k
1.38 x 10 s and k
/K 2.33 x 10 M
s . Several sulfonamide
inhibitors, from which many are clinically used, showed submicromolar or
nanomolar inhibitory effects on SmaBCA. The most efficient inhibitor
with a K of 43.8 nM was
4-(2-amino-pyrimidine-4-yl)-benzenesulfonamide. Other effective
inhibitors with K s in the range of 79.4 nM-95.9 nM
were benzolamide, brinzolamide, topiramate, dorzolamide, saccharin,
epacadostat, celecoxib, and famotidine. The other tested compounds
showed at least micromolar range inhibition against SmaBCA. Our results
introduce SmaBCA as a novel target for drug development against
schistosomiasis, a highly prevalent parasitic disease.
Community perspectives on the prospect of lion (Panthera leo) reintroduction to Comoé National Park, Côte d’Ivoire
Authors: Janvier AGLISSI , Aïkpémi SOGBOHOSSOU Etotépé , Hans Bauer
Published: January 2023

The civil war in Côte d’Ivoire between 2002 and 2010 led to a hike in
human disturbances and the disappearance of African lions (Panthera leo)
from the Comoé National Park (CNP). After the crisis, many efforts to
conserve and restore this ecosystem and its biodiversity have been made
and the management authority is considering the reintroduction of lions.
We assessed the acceptance of the reintroduction of the lions by the
local populations; through a sociological survey, we administered
questionnaires to 307 people in 23 villages bordering CNP. A large
majority (71%, n=218) were in favor of the return of the lions, with
significant variation among ethnic groups. A general linear model
analysis (GLM) revealed that apart from ethnic group, profession and
origin (village) are significantly determinant for the acceptance of
lion reintroduction to CNP. Most respondents had knowledge of the
species (96%, n=296). The majority of respondents (81%, n=250)
acknowledged having coexisted with lions, with previous conflicts with
lions reported by 16% (n = 49) of respondents and a willingness to
coexist with future lions reported by 81% (n = 248) of respondents.
More than 84% (n=260) of respondents believed that there would be
benefits associated with lion return to CNP and 52% (n=161) and 14%
(n=44) of respondents believed that the potential benefits would be
greater and less than the possible risks associated with lion return.
Just under half of respondents (42%; n=129) confirmed the current
participatory management of CNP while the majority (91%; n=280)
confirmed the possibility of taking own precautions to prevent attacks
from future lion. We recommend the improvement of the involvement of
indigenous communities in any reintroduction and the implementation of
environmental education projects as a condition for the potential
reintroduction of lions.
DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity
Authors: Parveen Nazia , Wang Jean Kimi , Bhattacharya Supriyo , Cuala Janielle , Rajkumar Mohan Singh , Butler Alexandra E. , Wu Xiwei , Shih Hung-Ping , Georgia Senta K. , Dhawan Sangeeta
Published: January 2023

The molecular and functional heterogeneity of pancreatic β-cells is well recognized, but the underlying mechanisms remain unclear. Pancreatic islets harbor a subset of β-cells that co-express tyrosine hydroxylase (TH), an enzyme involved in synthesis of catecholamines that repress insulin secretion. Restriction of the TH+ β-cells within islets is essential for appropriate function in mice, such that a higher proportion of these cells corresponds to reduced insulin secretion. Here, we use these cells as a model to dissect the developmental control of β-cell heterogeneity. We define the specific molecular and metabolic characteristics of TH+ β-cells and show differences in their developmental restriction in mice and humans. We show that TH expression in β-cells is restricted by DNA methylation during β-cell differentiation. Ablation of de novo DNA methyltransferase Dnmt3a in the embryonic progenitors results in a dramatic increase in the proportion of TH+ β-cells, whereas β-cell–specific ablation of Dnmt3a does not. We demonstrate that maintenance of Th promoter methylation is essential for its continued restriction in postnatal β-cells. Loss of Th promoter methylation in response to chronic overnutrition increases the number of TH+ β-cells, corresponding to impaired β-cell function. These results reveal a regulatory role of DNA methylation in determining β-cell heterogeneity.
Severe COVID-19 Infection in Type 1 and Type 2 Diabetes During the First Three Waves in Sweden
Authors: Edqvist Jon , Lundberg Christina , Andreasson Karin , Björck Lena , Dikaiou Pigi , Ludvigsson Johnny , Lind Marcus , Adiels Martin , Rosengren Annika
Published: January 2023

OBJECTIVE

Type 2 diabetes is an established risk factor for hospitalization and death in COVID-19 infection, while findings with respect to type 1 diabetes have been diverging.

RESEARCH DESIGN AND METHODS

Using nationwide health registries, we identified all patients aged ≥18 years with type 1 and type 2 diabetes in Sweden. Odds ratios (ORs) describe the general and age-specific risk of being hospitalized, need for intensive care, or dying, adjusted for age, socioeconomic factors, and coexisting conditions, compared with individuals without diabetes. Machine learning models were used to find predictors of outcomes among individuals with diabetes positive for COVID-19.

RESULTS

Until 30 June 2021, we identified 365 (0.71%) and 11,684 (2.31%) hospitalizations in 51,402 and 504,337 patients with type 1 and 2 diabetes, respectively, with 67 (0.13%) and 2,848 (0.56%) requiring intensive care unit (ICU) care and 68 (0.13%) and 4,020 (0.80%) dying (vs 7,824,181 individuals without diabetes [41,810 hospitalizations (0.53%), 8,753 (0.11%) needing ICU care, and 10,160 (0.13%) deaths). Although those with type 1 diabetes had moderately raised odds of being hospitalized (multiple-adjusted OR 1.38 [95% CI 1.24–1.53]), there was no independent effect on ICU care or death (OR of 1.21 [95% CI 0.94–1.52] and 1.13 [95% CI 0.88–1.48], respectively). Age and socioeconomic factors were the dominating features for predicting hospitalization and death in both types of diabetes.

CONCLUSIONS

Type 2 diabetes was associated with increased odds for all outcomes, whereas patients with type 1 diabetes had moderately increased odds of hospitalization but not ICU care and death.