bluuebunny/crossref_metadata_2025 huggingface dataset:
Crystal structure of 3,5-bis(trifluoromethyl)benzyl (Z)-N′-(adamantan-1-yl)-4-phenylpiperazine-1-carbothioimidate, C30H33F6N3S
Authors: Al-Wahaibi Lamya H. , Al-Shaalan Nora H. , Ghabbour Hazem A. , Tiekink Edward R.T. , El-Emam Ali A.
Published: May 2019

C30H33F6N3S, triclinic, P1̄ (no. 2), a = 9.3012(5) Å, b = 10.2734(5) Å, c = 15.1850(8) Å, α = 81.982(2)°, β = 78.696(2)°, γ = 83.882(2)°, V = 1404.25(13) Å3, Z = 2, R
gt(F) = 0.0779, wR
ref(F
2) = 0.2499, T = 293(2) K.
Effect of molecular weight of polyvinylpyrrolidone on the skin irritation potential and properties of body wash cosmetics in the coacervate form
Authors: Bujak Tomasz , Wasilewski Tomasz , Nizioł-Łukaszewska Zofia
Published: May 2019

Body wash cosmetics are among the most common groups of cosmetics used by consumers. Faced with strong competition in the marketplace, cosmetic manufacturers search for innovative solutions both in terms of product composition and form. An example of an innovative technology which can be used in the production of body wash cosmetics is the process of coacervation which yields a concentrated body wash product. Another important aspect which needs to be considered in the formulation of body wash cosmetics is their safety of use. It is crucial to ensure that such cosmetic products do not induce skin irritations. At present, the most widespread method of reducing the skin irritation potential of cosmetic products is the use of surfactant mixtures. The study is an attempt to evaluate the effect of using polyvinylpyrrolidone in the formulations of model body wash cosmetics in the coacervate form on the skin irritation potential and basic quality determinants of body wash products. Polyvinylpyrrolidone was found to contribute to a significant reduction in the irritant effect, and the skin irritation potential decreased in proportion to increasing molecular mass of the polymer. The application of polyvinylpyrrolidone with the different molecular weight also has an impact on improving the foaming properties of model body wash cosmetics and the stability of foam they produce.
Theoretical and experimental study of high-pressure synthesized B20-type compounds Mn1−

x
(Co,Rh)
x
Ge
Authors: Chtchelkatchev Nikolay M. , Magnitskaya Maria V. , Sidorov Vladimir A. , Fomicheva Ludmila N. , Petrova Alla E. , Tsvyashchenko Anatoly V.
Published: May 2019

The search and exploration of new materials not found in nature is one of modern trends in pure and applied chemistry. In the present work, we report on experimental and ab initio density-functional study of the high-pressure-synthesized series of compounds Mn1−

x
(Co,Rh)
x
Ge. These high-pressure phases remain metastable at normal conditions, therewith they preserve their inherent noncentrosymmetric B20-type structure and chiral magnetism. Of particular interest in these two isovalent systems is the comparative analysis of the effect of 3d (Co) and 4d (Rh) substitution for Mn, since the 3d orbitals are characterized by higher localization and electron interaction than the 4d orbitals. The behavior of Mn1−

x
(Co,Rh)
x
Ge systems is traced as the concentration changes in the range 0 ≤ x ≤ 1. We applied a sensitive experimental and theoretical technique which allowed to refine the shape of the temperature dependencies of magnetic susceptibility χ(T) and thereby provide a new and detailed magnetic phase diagram of Mn1−

x
Co
x
Ge. It is shown that both systems exhibit a helical magnetic ordering that very strongly depends on the composition x. However, the phase diagram of Mn1−

x
Co
x
Ge differs from that of Mn1−

x
Rh
x
Ge in that it is characterized by coexistence of two helices in particular regions of concentrations and temperatures.
Effect of gas on the polymer temperature in external gas-assisted injection molding
Authors: Li Taidong , Li Jiquan , Desplentere Frederik , Xia Xinxin , Peng Xiang , Jiang Shaofei
Published: May 2019

The introduction of gas is the principal difference between external gas-assisted injection molding (EGAIM) and conventional injection molding. In this study, the effects of gas thickness and gas delay time on polymer temperature were discussed. A modified one-dimensional transient heat conduction model of polymer was established to reveal the relationships between polymer temperature and gas thickness and gas delay time in EGAIM. The temperature histories of polymer were obtained by the simulation methods, including Moldflow and ANSYS, and were verified by comparing the experimental data to numerical simulation results. The effects of gas thickness and gas delay time on the temperature histories of polymer will be discussed in detail. The results showed that the polymer temperature is strongly affected by the heat preservation of gas, which in turn, increases with the increase of gas thickness and delay time. This paper provides quantitative methods and theoretical guidance for the study of the effects of gas on the polymer temperature in EGAIM.
Homogenous recycling of transuranium elements from irradiated fast reactor fuel by the EURO-GANEX solvent extraction process
Authors: Malmbeck Rikard , Magnusson Daniel , Bourg Stéphane , Carrott Michael , Geist Andreas , Hérès Xavier , Miguirditchian Manuel , Modolo Giuseppe , Müllich Udo , Sorel Christian , Taylor Robin , Wilden Andreas
Published: May 2019

The EURO-GANEX process was developed for co-separating transuranium elements from irradiated nuclear fuels. A hot flow-sheet trial was performed in a counter-current centrifugal contactor setup, using a genuine high active feed solution. Irradiated mixed (carbide, nitride) U80Pu20 fast reactor fuel containing 20 % Pu was thermally treated to oxidise it to the oxide form which was then dissolved in HNO3. From this solution uranium was separated to >99.9 % in a primary solvent extraction cycle using 1.0 mol/L DEHiBA (N,N-di(2-ethylhexyl)isobutyramide in TPH (hydrogenated tetrapropene) as the organic phase. The raffinate solution from this process, containing 10 g/L Pu, was further processed in a second cycle of solvent extraction. In this EURO-GANEX flow-sheet, TRU and fission product lanthanides were firstly co-extracted into a solvent composed of 0.2 mol/L TODGA (N,N,N′,N′-tetra-n-octyl diglycolamide) and 0.5 mol/L DMDOHEMA (N,N′-dimethyl-N,N′-dioctyl-2-(2-hexyloxy-ethyl) malonamide) dissolved in Exxsol D80, separating them from most other fission and corrosion products. Subsequently, the TRU were selectively stripped from the collected loaded solvent using a solution containing 0.055 mol/L SO3-Ph-BTP (2,6-bis(5,6-di(3-sulphophenyl)-1,2,4-triazin-3-yl)pyridine tetrasodium salt) and 1 mol/L AHA (acetohydroxamic acid) in 0.5 mol/L HNO3; lanthanides were finally stripped using 0.01 mol/L HNO3. Approximately 99.9 % of the TRU and less than 0.1 % of the lanthanides were found in the product solution, which also contained the major fractions of Zr and Mo.
Modeling the sorption of Np(V) on Na-montmorillonite – effects of pH, ionic strength and CO2
Authors: Scholze Raphael , Amayri Samer , Reich Tobias
Published: May 2019

Results from batch type experiments were modeled using the 2 SPNE SC/CE model developed by Bradbury and Baeyens. This work focused on the applicability of this model to the sorption of Np(V) on Na-montmorillonite under high saline conditions (0.1–3.0 M NaCl) in the pH range of 2–10 and in the presence of dissolved CO2 (p(CO2) = 10−3.3 atm). Under ambient air conditions two additional surface complexation species had to be taken into account, which are ternary species involving one carbonate ligand (≡SONpO2(CO3)2−, ≡SONpO2(CO3)Na−). The gained set of complexation parameters was successfully tested over a wide range of Np(V) concentrations (10−4 to 10−12 M) under Ar atmosphere and ambient air condition.
Ceramics-based Drug Delivery System: A Review and Outlook
Authors: Zang Sitian , Chang Shijie , Shahzad M. Babar , Sun Xiaoting , Jiang Xiran , Yang Huazhe
Published: May 2019

The drug delivery system (DDS) is a hot spot in the field of medicine due to their favorable characteristics, such as the realizability of targeted therapy, sustained and controlled release of drug. Ceramic materials have abundant desirable properties, such as simple preparation, adjustable size and structure, surface area to volume ratio, desirable stability under physiological conditions and excellent biocompatibility, etc. Hence they have been successfully applied in the field of DDS considerably in decades, acting as drug carriers. Traditional ceramic materials refer to inorganic solid compound. They are mainly composed of carbides, oxides such as hydroxyapatite, tricalcium phosphate, silica, zeolite, and zirconia, etc. This review summarized the applications of the ceramic materials in the field of DDS in recent years, meanwhile the outlooks of future development were also proposed.
A review on the removal of hydrogen sulfide from biogas by adsorption using sorbents derived from waste
Authors: Ahmad Waseem , Sethupathi Sumathi , Kanadasan Gobi , Lau Lee Chung , Kanthasamy Ramesh
Published: May 2019

Biogas is a vital renewable energy source that could play an effective role in fulfilling the world’s energy demand, not only in heat and power generation but also as a vehicle fuel in the future. Unfortunately, due to impurities, biogas requires a series of upgrading steps, which affects its economics and sustainability. Hydrogen sulfide (H2S) is one of the impurities that economically and environmentally hinder the biogas utilization as a source of energy. H2S removal from biogas using different technologies was extensively studied and established. One of such technology is adsorption. Adsorption by solid sorbents is considered as a suitable removal technique for toxic gases such as H2S because of its simplicity, easy handling, and environmental friendly sorbents. In this review, the utilization of waste material-based sorbent for H2S removal was appraised. Other gaseous components of biogas such as siloxanes, CO2, etc., are out of the scope of this work. The potential and effectiveness of the waste-derived sorbents, either raw waste or modified waste, were summarized in terms of its characteristics, suitability, and sustainability. The review provides an insightful analysis of different types of wastes such as sewage sludge, food waste, forestry waste, fly ash, and industrial wastes as an alternative to commercial adsorbents to adsorb H2S gas. Based on the analysis, it was concluded that if these sorbents are to be successfully commercialized, its economic analysis, regeneration conditions, and potential utilization of the spent sorbents has to be further exploited. Nevertheless, there is a great prospectus in the future for these waste materials to be utilized as sorbents for H2S removal.
Monitoring and assessment of formaldehyde levels in residential areas from two cities in Romania
Authors: Neamtiu Iulia A. , Cimpan Tiberiu , Zhou Jieqiong , Schiopu Irina , Surcel Mihai , Lin Shao
Published: May 2019

Formaldehyde has become a ubiquitous contaminant in the air, and people are exposed to it worldwide. However, few studies have evaluated the temporal-spatial levels/changes of formaldehyde exposure at residences, and the relationship between its outdoor and indoor levels has been rarely examined. The aim of this study was to assess community formaldehyde exposure in Sebes and Aiud, Romania to identify: (1) home environment characteristics that may play an important role in exposure; and understand: (2) if there were differences in formaldehyde levels between the two cities; (3) if there were temporal variations within each city; and (4) whether outdoor formaldehyde levels influence indoor levels. We simultaneously performed indoor and outdoor active air sampling for formaldehyde at each investigated residential location over a 3-year period and analyzed the samples by gas chromatography with flame ionization detector (GC-FID). The mean values of indoor and outdoor formaldehyde levels in both cities fell in the range 0.014–0.035 mg/m3. The correlation analysis indicated mostly positive but not significant (p > 0.05) correlations between indoor formaldehyde and microclimate factors (temperature, humidity, pressure). Notably, home insulation was found to be significantly correlated with increased indoor formaldehyde levels. There were no significant differences in mean indoor or outdoor formaldehyde levels between Sebes and Aiud over the 3-year study period. When comparing the formaldehyde levels in both cities over the 3-year period, only outdoor formaldehyde levels were significantly higher in 2016, as compared to those in 2017 and 2018.
Cadmium toxicity: effects on human reproduction and fertility
Authors: Kumar Sunil , Sharma Anupama
Published: May 2019

Background

Cadmium (Cd) is a non-essential toxic heavy metal, an environmental toxicant, and toxic at a low concentration, and it has no known beneficial role in the human body. Its exposure induces various health impairments including hostile reproductive health.

Objective

The present review discusses the information on exposure to Cd and human reproductive health impairments including pregnancy or its outcome with respect to environmental and occupational exposure.

Methods

The present review provides current information on the reproductive toxic potential of Cd in humans. The data were collected using various websites and consulting books, reports, etc. We have included recent data which were published from 2000 onward in this review.

Results

Cd exposure affects human male reproductive organs/system and deteriorates spermatogenesis, semen quality especially sperm motility and hormonal synthesis/release. Based on experimental and human studies, it also impairs female reproduction and reproductive hormonal balance and affects menstrual cycles. Based on the literature, it might be concluded that exposure to Cd at low doses has adverse effects on both human male and female reproduction and affects pregnancy or its outcome. Further, maternal prenatal Cd exposure might have a differential effect on male and female offspring especially affecting more female offspring. Hence, efforts must be made to prevent exposure to Cd.

Conclusion

Cd affects both male and female reproduction, impairs hormone synthesis/regulation and deteriorates pregnancy rate or its outcome even at lower doses.
Behavioral and neurobiological alterations induced by chronic use of crack cocaine
Authors: Rosário Bárbara dos Anjos , de Nazaré Maria de Fátima Santana , Estadella Débora , Ribeiro Daniel Araki , Viana Milena de Barros
Published: May 2019

Crack cocaine is the crystal form of cocaine and can be smoked, and rapidly absorbed, and, in part for this reason, is potently addictive. It is hypothesized that crack cocaine is able to induce important changes in different tissues and organs, and thus dramatically alter behavior. Nevertheless, which alterations in the central nervous system are related to its frequent use is still a matter of discussion. The present study is a literature review of articles published between the years 2008 and 2018 on the theme ‘crack cocaine and brain’ available in PUBMED, MEDLINE, EMBASE, and Google scholar databases. The results show that the use of crack cocaine induces important behavioral, neuroanatomical, and biochemical alterations. The main behavioral sequelae include cognitive and emotional changes, such as increased anxiety and depressive symptoms, attention and memory deficits, and hyperactivity. Among the neurobiological alterations are reductions in the activity of the prefrontal, anterior cingulate cortex, and nucleus accumbens. Molecular changes include decreases in neurotrophic factors and increases in oxidative stress and inflammatory cytokines, which may be responsible for the morphological alterations observed. It is also hypothesized that these neurobiological changes might explain the emotional and cognitive dysfunctions experienced by crack cocaine addicts.
The structure of non-human cognitive neuroscience: an epistemological critique
Authors: Almeida Francisco
Published: May 2019

Every scientific practice rests on implicit unrevised theoretical assumptions. Neuroscience, in particular, focuses on a very controversial object of study-the brain and is therefore prone to tacitly embrace philosophical positions in its everyday workings. It is thus, of utmost importance, to develop a critique of the structure of neuroscientific investigation so as to understand what the uncovered pillars of the field are, what pitfalls they may implicate and how we can correct them. In this paper, I gather the first critiques in animal cognitive neuroscience and hope to establish the first step in a continuous process of revision. By applying a conceptual division of neuroscience into cognitive, behavioral and neurobiological theories, I point out the main problems in articulating the three, based on actual scientific practice rather than purely theoretical reasoning. I conclude by proposing developments on behavioral theory and set an initial critique on assumptions on both cognitive and neurobiological theories.
Actividades de imagen en las páginas Facebook de pediatras españoles: el caso de “Lucía, mi pediatra”
Authors: Mapelli Giovanna
Published: May 2019

La Web 2.0 ha cambiado las modalidades en las que se desarrolla el encuentro tanto entre médico y paciente como entre paciente y paciente. En particular, el médico tiene un deseo de imagen específico en relación con su rol y explota los nuevos canales comunicativos, como las redes sociales, para difundir nuevos contenidos y promover sus actividades, para potenciar la relación con el ciudadano o para amplificar sus ideas entre los profesionales.

En el marco de la pragmática sociocultural, este trabajo estudia las publicaciones en Facebook de una pediatra española y los comentarios correspondientes recibidos durante los años 2018 y 2019, con el objetivo de destacar las estrategias de imagen que el facultativo y los progenitores del paciente adoptan y los efectos que producen en la imagen de los interlocutores. Los resultados demuestran que el profesional recurre sobre todo a actividades de autoimagen y cortesía donde las categorías de autonomía y afiliación se ponen de manifiesto para crear un clima de confianza interpersonal. En las respuestas de los seguidores se observan actividades de cortesía valorizadora. Facebook se configura como unacibervitrinaen la que el médico realza su imagen mediante la autopromoción de sus actividades, y a través de las manifestaciones de interés y acuerdo y de cortesía positiva por parte de losamigosen la red social.
Investigation and isolation of peptide based antiglycating agents from various sources
Authors: Kani Hatice K. , Kocazorbaz Ebru K. , Zihnioglu Figen
Published: May 2019

Background

In this work, peptide based antiglycation agents from various sources against the advanced glycation endproducts (AGE) formation was investigated.

Materials and methods

As a source of peptides with deglycating activity, Glycine max, Hordeum vulgare, Triticum aestivum, Avena sativa, Prunus dulcis ve Juglans regia were used. The metal chelating activity and antioxidant activity were determined by Cu(II) chelating activity and CUPRAC (Cupric Reducing Antioxidant Capacity) methods. Antidiabetic activity was evaluated through BSA-glucose model.

Results

Most of the extracts obtained have inhibitory activity against AGE formation. Among all plant peptide isolates soybean was found to be most efficient by means of antiglycating (IC50 1.33 μg/mL), antioxidant (28.2 ± 1.4 μmol AAE/mg) and metal chelation activity (55%).

Conclusion

As a result, this study can provide preliminary data to literature to support researches those focused on peptide based glycation inhibitors and discovery of potent AGE inhibitory peptides.
Harvesting the Electromagnetic Energy Confined Close to a Hot Body
Authors: Ben-Abdallah Philippe , Biehs Svend-Age
Published: May 2019

In the close vicinity of a hot body, at distances smaller than the thermal wavelength, a high electromagnetic energy density exists due to the presence of evanescent fields radiated by the partial charges in thermal motion around its surface. This energy density can surpass the energy density in vacuum by several orders of magnitude. By approaching a photovoltaic (PV) cell with a band gap in the infrared frequency range, this nonradiative energy can be transferred to it by photon tunnelling and surface mode coupling. Here we review the basic ideas and recent progress in near-field energy harvesting.
Synthesis, structure, and properties of nickel(II) and copper(II) coordination polymers with the 5-ethyl-pyridine-2,3-dicarboxylate ligand
Authors: Tang Long , Wang YingLu , Yin SiYu , Shi DeQian , Wang JiJiang , Wang Xiao
Published: May 2019

The reactions of Ni(NO3)2 · 6H2O/Cu(OAc)2 · H2O, 5-ethyl-pyridine-2,3-dicarboxylic acid (H2epda), and 2,2′-bipyridine (2,2′-bipy) under hydrothermal condition produced two new coordination polymers [Ni(Hepda)2(H2O)2] (1) and [Cu(epda)(2,2′-bipy)] (2), which were characterized by elemental analysis, infrared spectroscopy, thermogravimetric analysis, and single-crystal X-ray diffraction. In 1, each NiII center is six-coordinated in a distorted NiO4N2 octahedral geometry. Adjacent structural units are joined by strong intermolecular O–H · · · O hydrogen bonding to generate a layered structure. In 2, the CuII centers are bridged by epda dianions to form chains, where the 2,2′-bipy ligands bristle out on two sides, establishing π-π stacking interactions, Adjacent chains are thus aggregated in layers. The magnetic properties of 1 and 2 were investigated, and the exchange interactions were found to be −1.62 and −2.24 cm−1, respectively.
The bio-relevant metals of the periodic table of the elements
Authors: Sigel Helmut , Sigel Astrid
Published: May 2019

The bio-relevant metals (and derived compounds) of thePeriodic Table of the Elements(PTE) are in the focus. The bulk elements sodium (Na), potassium (K), magnesium (Mg), and calcium (Ca) from thes-block, which are essential for all kingdoms of life, and some of their bio-activities are discussed. The trace elements of thed-block of thePTEas far as they are essential for humans (Mn, Fe, Co, Cu, Zn, Mo) are emphasized, but V, Ni, Cd, and W, which are essential only for some forms of life, are also considered. Chromium is no longer classified as being essential. From thep-block metals only the metalloid (half-metal) selenium (Se) is essential for all forms of life. Two other metalloids, silicon and arsenic, are briefly mentioned, but they have not been proven as being essential for humans. All metals of thePTEand a plethora of their compounds are used in industry and many of them are highly toxic, like lead (Pb), which is discussed as a prime example. Several metals of thePTE, that is, their ions and complexes, are employed in medicine and we discuss the role of lithium, gallium, strontium, technetium, silver, gadolinium (the onlyf-block element), platinum, and gold.
Neue Aufgaben im Controlling durch digitale Transformation
Authors: Friedl Gunther
Published: May 2019

Die digitale Transformation wird das Controlling von Grund auf verändern. Die Zunahme der verfügbaren Datenmengen, neue Analysewerkzeuge, innovative Geschäftsmodelle und neue Arbeitsmethoden führen zu einem grundlegenden Wandel der Anforderungen an Controller. Das sichere Beherrschen von betriebswirtschaftlichen Steuerungsinstrumenten wie Planung, Budgetierung, Kostenmanagement und Reporting bleibt zwar weiter die Grundlage für die Tätigkeit des Controllers. Sein Wirkungsbereich wird sich allerdings ändern, weil die derzeitige technologische Entwicklung viele Standardaufgaben überflüssig macht und den Controller zwingt, sich über seine daraus resultierende Rolle und den persönlichen Weiterentwicklungsbedarf Gedanken zu machen. Damit eröffnet sich für den Controller die Chance, in seinem Unternehmen eine deutlich wichtigere Rolle als Berater und Partner des Managements einzunehmen.
A Guerra do Paraguai: Memórias e experiências de oficiais da marinha brasileira do Império à República Positivista
Authors: Viel Moreira Luiz Felipe
Published: May 2019

Este artículo se aboca al estudio de los recuerdos de veteranos de la Guerra del Paraguay, realizado básicamente a partir de memorias, cartas y un diario, documentos que integran la denominada “escrita de sí” y que fueron redactados por oficiales de la marina brasileña. Ellos traen diferentes miradas sobre la guerra, al mismo tiempo que relatan las experiencias que ayudan a entender los caminos personales de sus protagonistas frente a la transición de la monarquía a la república.
A nyaki ütőerek dissectiója – 19 eset retrospektív elemzése
Authors: Forró Csilla , Mészáros Zsófia , Sipos Márton , Kerényi Rita Zsuzsanna , Barsi Péter , Rudas Gábor , Bereczki Dániel , Vastagh Ildikó
Published: May 2019

Abstract:

Cervical artery dissection is a common cause of stroke in young adults. It might occur shortly after a forceful neck trauma or a minor injury. However, spontaneous dissection is also common, which is associated with genetic, anatomical or environmental risk factors. Cervical artery dissection can produce a broad spectrum of clinical presentation varying from local symptoms to focal neurological deficits determined by the arterial territory involved. Early recognition is important since immediate initiation of treatment can significantly improve patient outcomes. While clinical features may raise suspicion for dissection, the diagnosis has to be confirmed by neuroimaging findings. The purpose of this paper is to give an overview on cervical (carotid and vertebral) artery dissections while presenting 19 cases. During three years, we evaluated the clinical features, risk factors, diagnostic and therapeutic procedures of these patients admitted with extracranial artery dissection. The prognosis of the disease can vary, 42% of our patients became asymptomatic. Orv Hetil. 2019; 160(22): 861–868.
A középarc lágy részeinek nasolabialis függesztése: új, minimálinvazív és reverzibilis módszer az arc statikus szimmetrizálására végleges arcidegbénulásban
Authors: Vass Gábor , Bere Zsófia , Szabó Diána , Rovó László
Published: May 2019

Abstract:

Introduction: For the treatment of asymmetry of the midface due to permanent peripheral facial nerve palsy of different etiologies – which means a great psychical burden for the patients – several surgical solutions have been described. Aim: Our goal was to elaborate a minimally invasive surgical technique, that, on one hand, restores an adequate nasolabial fold, which is the most determinative keystone of facial symmetry. On the other hand, our technique can give an appropriate lift for the malar fat pad with shorter operative time and burden, with much lower complication rate and shorter recovery period compared to the classic static sling suspension techniques. Method: Out method is based on the formation of a neo-nasolabial fold, which is then suspended to the temporal fascia by permanent threads thus restoring facial symmetry and giving a lifting effect on the midfacial soft tissues as well. Results: Between 2014 and 2017, six patients had been operated with this nasolabial lifting technique of the malar fat pad without any major complications under local anesthesia on an outpatient basis at our Department. Conclusions: As our surgical exploration is minimal, the postoperative period is shorter, no visible scars remain on the face and the complication rate is negligible. If necessary, suspension could easily be adjusted, and as the technique is reversible, no other possible facial reconstruction methods are excluded. Our method can symmetrize the face in resting position completely on the long term, which is the most important issue for our patients according to their feedback. Orv Hetil. 2019; 160(22): 869–872.
Egy diagnosztikus kihívás: paraduodenalis pancreatitis. Két eset bemutatása
Authors: Hegedűs Ivett , Bogner Barna , Faluhelyi Nándor , Macygan András , Illés Anita , Kelemen Dezső
Published: May 2019

Abstract:

The paraduodenal, or groove pancreatitis is a lesser-known type of chronic pancreatitis, often mimicking malignancy, hence resulting in serious differential diagnostic challenges. Herein we report two cases of this entity. Both required analysis of the surgical specimen in order to ensure the diagnosis due to inadequate preoperative histological sampling and a vague clinical presentation. In the first case, strong suspicion of malignancy following imaging, while in the second, severe gastric outlet stenosis indicated the resection. In our report, we give a clinicopathological summary from the literature of this entity, including its epidemiology, clinical presentation and applicable diagnostic methods as well as macroscopic and microscopic pathomorphology. The pathogenesis of this disease is complex. Beside the role of alcohol, anatomic variations of the pancreatic ductal system, pancreatic islets in duodenal wall resulting from incomplete involution of dorsal pancreas, or Brunner gland hyperplasia (often observed as part of the lesion) can all play a role in the disturbance of pancreatic fluid discharge in the minor papilla area, eventually leading to this specific localised inflammation. In addition, recent investigations revealed a susceptible role of genetic polymorphism in the persistent inflammatory disorders of the pancreas. Besides summarizing the differential diagnostic aspects, we also discuss therapeutic possibilities, underlining the conservative methods, which can be used with good efficacy after a successful identification of this entity. Orv Hetil. 2019; 160(22): 873–879.
Hepatitis C-vírus-fertőzés és hepatocarcinogenesis
Authors: Berta Evelin , Egresi Anna , Bacsárdi Anna , Gáspár Zsófia , Lengyel Gabriella , Hagymási Krisztina
Published: May 2019

Abstract:

Hepatitis C virus infection causes approximately 4 million new infections worldwide, and 399 000 deaths due to its complications, cirrhosis and hepatocellular carcinoma (HCC). Microenvironmental changes, chronic inflammation, oxidative stress, endoplasmic reticulum stress caused by HCV infection, via genetic and epigenetic changes can result in primary liver cancer during decades. The direct oncogenic property of HCV is wellknown. The transforming effect of four HCV proteins (core, NS3, NS4B, NS5A) has been proven. Effective antiviral therapy, sustained viral response decreases the HCV-related general and liver-related mortality. Interferon-based therapy reduces the risk of HCC development. Shorter therapy with direct acting antiviral agents (DAA) has higher efficacy, fewer side-effects. Publications have reported the unexpected effects of DAA. The authors review the articles focusing on the occurrence of HCC in connection with DAA therapies. There is a need for prospective, multicentric studies with longer follow-up to examine the risk of HCC formation. After antiviral therapy, HCC surveillance is of high importance which means abdominal ultrasound every 3–6–12 months in sustained viral response patients as well. Orv Hetil. 2019; 160(22): 846–853.
Nemszteroid gyulladáscsökkentő szerek a mozgásszervi fájdalom csillapításában
Authors: Sütő Gábor
Published: May 2019

Abstract:

Pain control in musculoskeletal disorders is still a challenging task. The most effective treatment of pain in autoimmune and immune-mediated diseases is the treatment of the disease itself. Analgesics, non-steroidal anti-inflammatory drugs and opioids are used to relieve pain. Analgesia is the central intervention of degenerative disorders. The most effective analgesic compounds are the non-steroidal anti-inflammatory drugs (NSAIDs). Concerns are raised regarding the safety of NSAIDs. There is not any organ which is not involved in adverse reactions, but the damage of the gastrointestinal system has been considered the most serious one for a long time. In the 21st century, the recognition of cardiovascular complications led to the re-evaluation of the role of these drugs in analgesia. Orv Hetil. 2019; 160(22): 855–860.
The Basic Principles of Information Protection in the Russian Federation in the Transition to a Digital Economy
Authors: Romanov Rashit
Published: May 2019

The modern stage of development of society is characterized by the increasing role of the information sphere. The information sphere is a set of information, information infrastructure, entities engaged in the collection, formation, distribution and use of information, as well as a system of regulation of public relations arising in this process.
The expansion of the areas of application of information technologies, as a factor of economic development and improvement of the functioning of public and state institutions, at the same time generates new information threats. The situation is significantly complicated by the confrontation between the Russian Federation and the West, which directly affects the sphere of national interests of the Russian Federation and poses a direct threat to the national security of the country, the key element of which is information security.
There is a constant growth of computer attacks on Russian information resources, the number of attacks has increased significantly in recent years. At the same time, the methods, means and tactics of such attacks are being improved, and their intensity directly depends on the current international situation.
Terrorist and extremist materials are openly distributed in the global network. The number of crimes committed with the use of information technologies, for example, illegal penetrations into the corporate networks of state and credit and financial institutions, has increased. The article analyzes the requirements for the security of important objects of critical information infrastructure of the Russian Federation. It is shown that they should be performed at all stages of the life cycle during the creation (modernization), operation and decommissioning of a significant object.
Envisioning Possibilities for Innovations in Higher Education Research on Race and Ethnicity
Authors: Stewart D-L
Published: May 2019

This article uses the Sankofa principle of going back and getting that which can enable a community to imagine new possibilities. In this article, four waves of current research in race and ethnicity in higher education are offered, as well as some lessons learned from them.  These considerations provide the backdrop for imagining how a fifth wave may be ontologically and epistemologically oriented, what themes it might take up, and its possible implications.
Comparação: implícita, explícita e valor
Authors: Dullo Eduardo
Published: May 2019

Resumo Desde os primórdios da disciplina os/as antropólogos/as fizeram uso de formas de comparação (entre práticas, sociedades, culturas, civilizações). Entretanto, nas últimas décadas do século XX e na primeira década do século XXI sua condição metodológica foi repensada como consequência de alguns desenvolvimentos teóricos críticos dos conceitos de cultura e sociedade, colocando novas questões acerca das unidades de análise a serem investigadas. A presente reflexão visa pontuar a mudança recente de revitalização da comparação como parte explícita (ou epistemológica) da reflexão antropológica - e não apenas como a dimensão implícita, isto é, o (sempre presente) pressuposto da análise. Argumento que a transição de sua condição implícita para explícita decorre da sua posição como um valor.
PERSONAGENS DE TIRAS CÔMICAS: AQUISIÇÃO DE LINGUAGEM NO HUMOR E NA FICÇÃO
Authors: GATTI Márcio Antônio
Published: May 2019

RESUMO Este artigo analisa, em consonância com os estudos interacionistas da área de Aquisição da Linguagem, a fala de personagens infantis de tiras cômicas. Entre outros aspectos analisa a verossimilhança dessas falas e argumenta sobre a necessidade de relacionar os dados oriundos da ficção com dados já colhidos por pesquisadores da área, se a esses dados fictícios quiser se recorrer como material de trabalho. Por outro lado, aborda os dados (as tiras) como um relevante material para se observar como se representam, na ficção, a própria fala da criança e os efeitos que ela produz nos seus interlocutores, dado o fato que as tiras são textos produzidos por autores adultos que de alguma forma devem tornar verossímil a fala infantil. Observando que as tiras são textos produzidos para obter algum efeito de humor, o artigo argumenta, ainda, que o efeito de humor produzido pelas tiras não se relaciona ou relaciona-se muito sutilmente com o efeito cômico produzido por algumas falas reais de crianças.
SELEÇÃO LEXICAL E RELAÇÕES SEMÂNTICAS DAS CO-OCORRÊNCIAS DE GÊNERO E SEXUALIDADE NOS PARÂMETROS CURRICULARES NACIONAIS
Authors: VIEIRA Viviane Cristina , GONZALEZ Carolina Gonçalves
Published: May 2019

RESUMO Serão apresentadas reflexões iniciais da pesquisa de doutorado Identidade de gênero no espaço escolar: possibilidades discursivas para superação da heteronormatividade, de Gonzalez (2017), desenvolvida no âmbito projeto “Corpos e identidades como práticas sociodiscursivas: estudos em Análise de Discurso Crítica”. Cumprindo nosso compromisso científico e político com a explanação crítica, em práticas sociais situadas, dos modos de agir e se relacionar (as inter-ações); construir sistemas de conhecimento (as representações) e, ainda, dos modos de ser e de identificar (as identificações) parcialmente (con)formadores de poderes-saberes-subjetividades em relações de gênero, discutimos aqui um aspecto do complexo processo social em curso que é a construção dos conceitos de “gênero social” e de “sexualidade” nos documentos político-pedagógicos nacionais, especificamente, aqui, nos Parâmetros Curriculares Nacionais. Concluímos que há atores como a família e a escola que são avaliados negativamente assim como a sexualidade e o gênero são tomados como um conceito único e indistinto, possuindo distintas relações com campos semânticos conceituais e co-ocorrências com termos que constroem suas redes semânticas de significados.
Comparison of modelling techniques for assessment of spillways
Authors: Green James
Published: May 2019

Theoretical equations, computational fluid dynamics (CFD) and physical modelling are the three main commonly and commercially used techniques to analyse the performance of current or proposed dam spillways. The purpose of this paper is to compare the aforementioned modelling techniques, and ascertain the most appropriate application for pertinent features commonly required for analysis on a typical spillway. My employment allows me the unique opportunity to explore each technique with a critical analysis of individual performance and accuracy. It also allows me access to a great deal of physically modelled dam spillway data, against which to validate the CFD model to ensure accuracy. The paper will study each technique if applicable for the following pertinent requirements: Q/H curve, out-of-channel flow, velocity profiles, energy dissipation, pressure and hydraulic profile.
Modelling study of hydrodynamics in a macro tidal estuary
Authors: Zhang Jisheng , Wang Rui , Guo Yakun , Wu Xiuguang , Zheng Jinhai , Zhang Zhiyong
Published: May 2019

A depth-averaged two-dimensional (2D) numerical model was developed to investigate hydrodynamics in estuaries. The Qiantang estuary is taken as a demonstrative case study. The Qiantang estuary is famous for its macro tide during the spring tide and the Qiantang bore, which poses a challenging task for accurate simulation. In this study, the model was setup to simulate the tidal elevations and the tidal velocity field in the Qiantang estuary. A mesh sensitivity analysis was carried out to optimise the mesh arrangement to achieve computational efficiency while retaining computational accuracy. The simulation results showed that, in general, the numerical simulation agreed well with the field observations, indicating that the developed 2D model can be applied to calculate hydrodynamics in a macro tidal estuary. Some deviation between the simulation and measurements at some locations exists and this discrepancy is analysed and discussed.
Exploring the interaction between Science teachers’ self-efficacy beliefs and pedagogical discontentment: An attempt to understand why science education reform fails
Authors: Keklikci Nesrin , Saka Yavuz
Published: May 2019

Scientific literacy is currently one of the main purposes of science education. Science education reform efforts provide rich, comprehensive and explicit messages, ideas suggestions with teachers to promote scientific literacy through student-centered and inquiry-based instructional implementations. However, systemic change that reform aims to achieve yet to come through as most of the science teachers are still using teacher-centered lecture style science teaching rather than implementing reform initiatives. The purpose of this paper is an attempt to shed light on the existing literature to understand why science teachers would not employ reform initiatives in their classrooms. Teacher self-efficacy and pedagogical discontentment are selected to be the target constructs that the interactions between them hold promises to explore teacher averseness to reform. 130 science teachers working in public middle schools located in northern Turkey were participated in this study. The findings derived from this research provided several key interactions between self-efficacy beliefs and pedagogical discontentment in terms of the participating teachers’ openness toward science education reform in Turkey. Methodological implications were also embraced.
The Romanian Version of the Revised Youth Purpose Survey (RYPS): Psychometric Evaluation for Emerging Adults
Authors: Balgiu Beatrice Adriana
Published: May 2019

The present article looks into the psychometric properties of the Revised Youth Purpose Survey

(RYPS) in the case of a group of Romanian students emerging adults (N = 500). RYPS is a ten‐item

scale made of two sub‐scales which measure Purpose Exploration (4 items) and Purpose

Commitment (6 items). Confirmatory factorial analysis indicated an adequate fit of a two‐factor

model (GFI = .96; AGFI = .94; RMSEA = .057). This structure was confirmed and it was invariant for

gender. Cronbachʹs alpha coefficients show good internal consistency: .87 (Purpose Exploration

subscale) and .77 (Purpose Commitment subscale). The correlations of both scales of RYPS with

validation measures of psychological and subjective well‐being and of identity orientations were

positive, indicating good convergent validity. The study validated the conceptual vision of the

authors of the instruments in a previously unstudied cultural context.
Smartphone Addiction and Leisure Constraints: College Students
Authors: SOYER Fikret
Published: May 2019

The aim of this study was to investigate the leisure constraints perceived by the university students according to the level of smartphone addiction. In the study, in order to determine the constraints faced by the participants Leisure Constraints Scale developed by Alexandris and Carroll (1997), adapted to Turkish by Gürbüz, Öncü, and Emir (2012) and in order to determine the level of smartphone addiction, Smartphone Addiction Scale developed by Kwon et al. (2013) and adapted to Turkish by Noyan et al. (2015), was used. Conventional sampling method was preferred for sample selection and face-to-face survey method was used for data collection. In the analysis of the obtained data, descriptive statistics, Independent Sample t-test, One-way ANOVA, Chi-square, Hierarchical and non-hierarchical clustering analysis were used. A total of 1298 volunteers participated in the study: 676 males (52.1%) and 622 females (47.9%). According to the results of the study, it was determined that there was a statistically significant difference in the subscales of leisure constraints in terms of individual psychology, lack of knowledge, lack of friends, lack of time and interest according to smartphone addiction levels. As a result; It was determined that the high-level smartphones addicted students perceived a high level of leisure constraints than the university students who had a low level of addictions.
Investigation of High School Students' Internet Parental Styles in Relation with Several Variables
Authors: Selvi Harika , Horzum Mehmet Barış , Üngören Yasin
Published: May 2019

The aim of this study is to investigate internet parental styles of high school students in terms of gender, grade and parental warning. The sample of the study consists of high school students, who were selected through convenience sampling method, studying in the city of Sakarya. In this study, Ayas and Horzum (2013), the Turkish version of ‘’Internet Parental Style Scale’’, was used. The scale was developed in Dutch by Rooij and Eijden (2007) and translated into English by Valcke et al. (2010). The scale has two sub-dimensions: family control and family intimacy. The findings of the study revealed that internet parental styles of high school students differed according to gender and grade, but it did not show a significant difference according to the parental warning.
A Investigate of Influence Factor for Tertiary Students’ M-learning effectiveness: Adjust Industry 4.0 & 12-Year Curriculum of Basic Education
Authors: Chou Chun-Mei , Shen Tsu-Chguan , Shen Chien-Hua , Hsiao Hsi-Chi
Published: May 2019

Mobile learning (M-learning) as a technology teaching has significant potential to improve student application and comprehension skills. The rapid development of the Internet and the resulting trends applying information available on the Internet have changed the nature of learning and learning behavior patterns of tertiary students. However, insufficient theoretical and empirical research on the effect of M-learning on learning attitude and M-learning effectiveness has been conducted for achieving any reliable understanding of the use of M-learning by tertiary students. This, study was therefore based on the theory of planned behavior, and combined the technology acceptance model and the structural equation model (SEM); it involved 892 tertiary student participants, and developed an empirical research model. The study found that in terms of M-learning acceptance, tertiary students have a positive evaluation and perception of using M-learning, with perceived enjoyment being the most significant factor. In addition, the impact of perceived innovation was significant in helping teachers understand students’ learning outcomes. The teaching material of learning motivations was also significant, indicating that current tertiary students are more likely to value their friends as sources of information. External influences on self-efficacy were also significant, suggesting that teachers must consider the ability of M-learning technology, with particular attention paid to students’ competency with the technology itself, as difficulty of use will reduce students’ willingness to use M-learning.
Sleep Quality and Self-compassion as Predictors of Aggression in High School Students
Authors: İskender Murat , Şar Ali Haydar , Özçelik Basri , Kocaman Gökçe
Published: May 2019

In the current study, the relationships between Aggression, Self-compassion and Sleep Quality of high school students have been examined. 529 high school students (66% females and 34% males) participated in the study. Data were collected from participants through using a Pittsburgh Sleep Quality Index (PSQI), Aggression Questionnaire (AQ), Self-Compassion Scale (SCS), and Descriptive Questionnaire. The predictors of aggressiveness of the variables determined by simple correlation were investigated by multiple linear regression. According to the results, there was a positive and significant relationship between aggression levels and all sub-dimensions of self-compassion and sleep quality. In addition, it was observed that the levels of aggressiveness were significantly predicted by the sub-dimensions of self-compassion and sleep quality, and that the first three most effective predictive variables were over-identification, self-judgment and sleep quality.