bluuebunny/crossref_metadata_2025 huggingface dataset:
Prediction Of Carboxylic Acid Toxicity Using Machine Learning Model
Authors: Mohamed Zabidi Zubainun , Muhamad Suhaimy Nurul Batrisyia , Alias Ahmad Nazib , Fuadi Nur Diyana Nazihah , Hamzi Nur Hanisah
Published: October 2023

Carboxylic acids are organic compounds characterized by the presence of a carboxyl functional group capable of donating a proton and forming carboxylate ions in aqueous solutions. The carboxylic acid has widely been used in in manufacturing and medical applications. The rapid growth in carboxylic acid has established a need to predict its toxicity. The purpose of this paper to build predictive toxicity of carboxylic acid models by using five molecular descriptors (refractive index, The octanol/water partition coefficient (log P), acid dissociation constant (pKa), density, and dipole moment) through Machine Learning algorithms. The accuracy of the Machine Learning algorithm was determined by using three different types of models which are Decision Tree, Random Forest and k-Nearest Neighbour (k-NN). Among the machine learning algorithms used, we have determined that the decision tree is the best model for predicting the toxicity of carboxylic acid. This finding demonstrates that the decision tree model exhibits an acceptable level of performance in predicting toxicity within the field of toxicology.
Environmental Impact Assessment and Process Upscaling for Sustainable Production of Cellulose Nanofibre, a Biopolymer Derived from Lignocellulosic Biomass
Authors: Bulbul Gupta  , Amita Sharma  , Anjana, Subhasish Dutta  , Subhasish Dutta  , Saswata Goswami
Published: October 2023

As an agricultural waste, rice straw has a requisite quality for conversion to nanocellulose; however, the environmental and technical feasibility of the processes available has not been assessed at commercial scale. Therefore, in the present work commercialization and environmental impacts of the cellulose nanofibre (CNF) production from rice straw were evaluated by scaling up the laboratory-scale process to the pilot scale level. Life cycle assessment (LCA) of the laboratory scale process showed the maximum impact of electricity (161 kg CO2 eq) and sodium hydroxide (7.82 kg CO2 eq) on global warming potential; though, the overall impacts got reduced approximately three times (~51 kg CO2 eq for electricity) with the scale-up of the process. When compared with the reported literature both the scales of production were found to have lesser environmental impacts. Further, the techno-economic feasibility of the process was evaluated at different plant capacities for the optimum minimum selling price (MSP) of CNF. At the plant capacity of 15 kg/day, the MSP of CNF was calculated as $16,537.36/tonne dropped to $14,944.87 and $14,590.98/tonne with the increased batch capacity of 30 kg/day and 45 kg/day, respectively. Through sensitivity analysis, the MSP of CNF was observed to be highly sensitive to the cost of capital investment and chemicals cost. In addition, analysis of the uncertainty associated with the identified cost drivers reflects the scope for inherited risks, as determined by the Monte-Carlo simulation method. This study established an environmentally and economically sustainable process for commercialisation of nanocellulose production from agricultural waste at a minimum cost of production.
Network Pharmacology-Based Strategy to Reveal the Mechanism of Action of Cistanche Against Cataracts
Authors: Zeng Jian , Zhou Zonghan
Published: October 2023

Cistanche is known to relieve cataracts; however, the active ingredients and mechanism of action of cistanche to relieve cataracts are unclear. At present, the active ingredients of cistanche were screened through the Traditional Chinese Medicine Systems Pharmacology website, and a total of six active ingredients were identified. Drug and disease targets were obtained through Swiss target prediction and the Genecard website, and a total of 172 common targets were identified. The biological functions and Kyoto Encyclopedia of Genes and Genomes pathway enrichment of the targets were found to be concentrated in the phosphatidylinositol 3-kinase/protein kinase B, forkhead family of transcription factors, and mitogen-activated protein kinases pathways. The protein–protein interaction network was established, and phosphatidylinositol 3-kinase and protein kinase B-related genes were found to be the key genes. Molecular docking was carried out between the active ingredient and the key target, and it was found that the combination of the active ingredient and the key target was stable. In summary, cistanche can reduce cataracts by regulating the key targets of the active ingredients and thus alleviating cataracts.
HUBUNGAN KADAR HEMOGLOBIN DENGAN FUNGSI KOGNITIF SISWI SMP NEGERI 6 PALANGKA RAYA
Authors: Millie Gideon Christian Sonder , Sasmithae Lia , Teresa Astrid , Carmelita Austin Bertilova , Millie Gideon Christian Sonder
Published: October 2023

Masa remaja merupakan masa peralihan dari masa kanak-kanan ke dewasa muda.  Remaja putri usia 13-15 tahun lebih berisiko menderita anemia daripada remaja putra, karena remaja putri mengalami siklus awal haid dan menjalani pola diet yang tidak tepat. Anemia dapat menyebabkan suplai oksigen terganggu, tanpa suplai oksigen yang cukup sel-sel otak tidak dapat berkembang dan beraktivitas secara optimal. Oleh sebab itu, peneliti hendak melakukan penelitian melihat hubungan kadar hemoglobin dengan siswi SMP. Penelitian cross sectional ini dilakukan di SMP Negeri 6 Palangka Raya pada bulan Oktober 2023 dengan jumlah sampel sebesar 156 subjek. Rata-rata kadar Hb 12,8 dengan standart deviasi 1,4 dan nilai minimum skor Moca-Ina adalah 13 dan nilai maksimunya adalah 29. Setelah dilakukan analisa statistik secara bivariat dengan korelasi spearman didapatkan hubungan yang tidak signifikan antara kadar Hb dengan fungsi kognitif dengan nilai p=0,226.
Identifikasi larva nyamuk di Desa Lawang Uru Kabupaten Pulang Pisau
Authors: Augustina Indria , Palupi Didin Retno Endah
Published: October 2023

. In tropical nations like Indonesia, mosquitoes serve as carriers of viruses and parasites that can infect humans. Finding out which mosquito larvae species were present and where in Banama Tingang District—particularly in Lawang Uru Village—was the study's main goal. Descriptive survey research using simple random sampling methodology is what this study is. All of the mosquito larvae used in this study were collected from Lawang Uru Village. In residential areas, larvae are collected. Descriptive survey research using simple random sampling methodology is what this study is. All of the mosquito larvae used in this study were collected from Lawang Uru Village. In residential areas, larvae are collected. The study's findings revealed 232 larvae belonging to the following species: Culex quinquefasciatus, Aedes albopictus, Culex vishnui, and Aedes aegypti. utilized paint cans, tires, drums, boats, and livestock feeders were among the materials utilized to create larval breeding habitat in Lawang Uru Village.
Stem cell therapy in neurological disorders: promises and concerns
Authors: Hachimi-Idrissi Said
Published: October 2023

Self-neuronal regeneration is often limited or nonexistent after neuronal cell damage, making new technologies necessary for treating neurological damage. Although the brain can partially compensate by increasing its plasticity, these compensatory mechanisms can never fully restore the pre-damage state. Analysis of the literature regarding stem cell therapy in case of neurological disorders. Stem cells have shown promise for treating various neurological disorders and disabilities due to their regenerative capacity. Transplanting or administration of different types of stem cells has yielded promising results in animal models and early clinical trials. However, concerns remain regarding their implementation. The type of stem cell used, the optimal method and route of administration, the number of stem cells administered, preconditioning, and the injection schedule all need to be determined. Additionally, the long-term safety of stem cell treatment and the recipient’s age requires further investigation. Despite these concerns, stem cell therapy holds tremendous promise for treating neurological disorders, and continued research and well-designed studies will be crucial for unlocking its full potential.
Discriminating Between Ordinary Least Squares Estimation Method and Some Robust Estimation Regression Methods
Authors: Idowu Badmus Nofiu , Kayode Ogundeji Rotimi
Published: October 2023

The lack of certain assumptions is common in ordinary least squares regression models whenever there is/are outliers and high leverage in the observations with an extreme value on a predictor variable. This could have a great effect on the estimate of regression coefficients. However, this research investigates the performance of the ordinary least squares estimator method and some robust regression methods which include: M-Huber, M-Bisquare, MM, and M-Hampel estimator methods. This study applies both methods to a secondary data set with 28 years (from 1900 to 2021) 200 meter races Summer Olympic Games with a response variable (sprint time) and three predictor variables (age, weight, and height) for illustration. Also, linearity, homoscedasticity, independence, and normality assumptions based on diagnostics regression like residual, normal Q-Q, scale-location, and cook’s distance were checked. Then, the results obtained show that the robust regression methods are more efficient than the ordinary least square estimator method.
Perancangan Ulang Heat Exchanger 5 Kilang PPSDM MIGAS Cepu dengan Kapasitas Crude oil 21.082 lb/jam dan Residu 4.578 lb/jam
Authors: Pradhito Agung
Published: October 2023

Penukar panas atau dapat disebut heat exchanger adalah alat yang digunakan untuk memindahkan panas antara dua atau lebih cairan. Salah satu jenis heat exchanger adalah STHE. STHE merupakan alat penukar panas yang terdiri dari shell yang didalamnya dipasang beberapa tube. Shell adalah silinder luar yang berisi beberapa tube dan akan dialiri suatu fluida. Shell and tube yang digunakan di kilang PPSDM Migas adalah jenis 2 phase Metode yang digunakan pada penelitian ini adalah metode kuantitatif yang kemudian diolah sehingga diharapkan hasil perhitungan yang dilakukan dapat menjawab rumusan masalah mengenai spesifikasi dan dimensi shell and tube heat exchanger 5 Kilang PPSDM MIGAS Cepu untuk dapat mengakomodasi kapasitas crude oil 21.082 lb/jam dan residu 4.578 lb/jam. Dari hasil perhitungan menunjukkan bahwa fouling factor desain berada pada angka 0,0035 dan pressure drop total bernilai 0,0044 psi. Hasil tersebut berada di bawah ambang batas fouling factor (0,05) dan pressure drop (10 psi) sehingga dimensi heat exchanger memenuhi standar-standar perancangan. Dimensi heat exchanger 5 berubah dalam hal ukuran diameter dalam (ID) shell menjadi 35 in dengan 522 buah tube dan panjang tube 16 ft. Satu pass shell dan tube pada heat exchanger masih dapat mengakomodasi kondisi operasi sehingga tidak perlu dilakukan perubahan jumlah pass.
Preoperative care dependency and postoperative quality of recovery of the surgical patients
Authors: Süerdem Bilkay , Dikmen Burcu Totur
Published: October 2023

Objective

The purpose of the study was to determine the relationship between preoperative care dependency and postoperative quality of recovery in patients undergoing surgery.
Methods

The sample of the descriptive, cross-sectional and correlational study consisted of 215 patients. A Patient Information Form, the Care Dependency Scale and the Recovery Quality-40 Scale were applied to the patients through face-to-face interview technique in order to collect the data between June and December 2018. This study adhered to Strengthening the Reporting of Observational Studies in Epidemiology guidelines.
Results

There was a statistically significant difference between Care Dependency Scale and the Recovery Quality-40 Scale mean scores of the patients and their physical comfort, physical independence, and pain in terms of age groups and genders (p<.05). A positive and moderate correlation was found between the patients’ care dependency and physical independence.
Conclusion

It was observed that when the care dependency level decreased, the patients needed less assistance throughout the postoperative recovery period, as they were able to carry out their daily activities independently.
Normative evaluation of emergency obstetric care in the prevention of COVID-19
Authors: Silva Sandra Cristina de Souza Borges , Acauan Laura Vargas , Cardoso Gisela Cordeiro Pereira , Paes Graciele Oroski , Trotte Liana Amorim Correa , Mouta Ricardo José Oliveira , Stipp Marluci Andrade Conceição
Published: October 2023

Objective

Evaluate the structure and care flow – risk classification and obstetric emergency in a public maternity hospital in the context of COVID-19.
Methods

Normative and observational evaluation study in the Care sectors (Risk Classification and Obstetric Emergency) of a public maternity hospital in Rio de Janeiro. Data collection was carried out from June to August 2020 for 480 hours of non-participant direct observation, with records systematized in a checklist containing variables related to the availability and compliance of structural resources, and the compliance of the care flow. Data were organized into spreadsheets (Microsoft Excel® 2010) and analyzed using descriptive statistics.
Results

The framework assessment scored 80.3% availability, resulting in a high availability rating, and 91.1% compliance, achieving adequate compliance. The care flow showed 72.7% of total compliance; 9.1% of partial compliance and 18.2% of non-compliance, configuring high compliance.
Conclusion

Normative evaluation indicated high availability and compliance in structure and care flow in the studied scenarios.
MENTAL SPACE AS A WAY OF PRESENTING AND STRUCTURING HUMAN KNOWLEDGE
Authors: MOISIUK Valentyna
Published: October 2023

The author raises one of the important issues of cognitive linguistics, namely the representation and structuring of knowledge that a person receives during their life and discursive activity. This research is based on the «theory of mental spaces» (G. Fauconnier and M. Turner), according to which language appears not only as an object of human interpretation, but also as a constructive principle: it creates mental spaces and determines the relationship between them. Mental spaces reflect reality, ways of thinking and speech of speakers. The main purpose is to model the mental space of the French adjective vert, its usual and new images, which allow demonstrating the way of obtaining, processing and storing human knowledge. The choice of idioms as research material is explained by the fact that these units vividly reflect the mentality of the representatives of the language community, the peculiarities of their vision and understanding of reality, and also demonstrate the cognitive mechanisms during the generation of new nominative units.
After analyzing the material, the author suggests that during the world perception and communication, mental spaces can build up structured information. They are divided into three spheres, each of which has its own images: sacred, profane and metaphorical. The study of new idioms showed that only 75% of them fit into the traditional model of the metaphorical sphere. The mental space of other units contains new images of the adjective vert, which complement different spheres and can further serve as the basis for the formation of new idioms.
SIGN LANGUAGES AS CONVENTIONAL SYSTEMS IN COMMUNICATION OF DEAF PEOPLE
Authors: GEORGIEVA Diyana
Published: October 2023

Sign languages are conventional communication systems that arise spontaneously in all deaf communities around the world. The current article offers a glimpse into the problem of the essence of a natural human language, which exists in a physical modality different from that inherent in vocal language, which has imposed its centuries-old monopoly as an object of study. The present theoretical study is aimed at building a comprehensive vision of sign languages, which, until recently, have been marginalized in research interests. A brief historical analysis of the whole cycle of arising research in the field of sign language linguistics is presented. A special focus is placed on the genealogical relationships of sign languages, the identification of which still remains in the realm of hypothetical reasoning, in contrast to spoken languages, where this is stated as a clearly defined scientific fact. A well-deserved place is given to the quantitative dimensions of sign languages in the contemporary world. Harmonized data collection in the world register of visual languages is clearly in a position of direct dependence on social and linguistic factors. The question of the non-homogeneous character of sign languages, determined by territorial and social variations, is also considered. Despite the contrasts identified at different linguistic levels, specific features inherently present in the deaf community can be found in the variations of visual languages.
THE FUNCTIONS OF THE CHARACTER/S IN THE NOVEL THE PALACE OF DREAMS BY ISMAIL KADARE
Authors: PROGNI Marjela , PECI Muhamet
Published: October 2023

The Palace of Dreams considering its anti-totalitarian meaning is a miracle of its own because it was published under the communist system of the time by virtue of the novel’s text’s coding in the best possible way. This feature, made the novel important, interesting and challenging to the scholars because it constitutes a literary model that can be studied from different points of view and still provides more new ones.
The aim of this paper is to examine the role of the character/s in decoding the hidden meaning layers of the novel by generally applying a formalist approach with a main focus on the structuralist method. These roles will be distinguished by performing a theoretical analysis regarding the involved components in their concretization, by carrying out stylistic analyses to decipher the figurative language and by utilizing these results through interpretive analyses thereby introducing yet another new way of studying the novel’s coded contexts: the first one related to the exposure of the totalitarian dictatorships, the second one related to ethnic identity and the role in terms of the position of Albanians in the socio-political life of the empire and additionally covering an unexplored area in the existing literature.
Mark-Alem is delegated multi-functional roles: he becomes a figure, a theme, an idea and a link that holds up the narrative discourse itself. He is the tool that makes the difference between the readers’ understanding of the “historical” events dealt with in this book and the coded contexts that lay under the storyline.
HASIDIC INFLUENCES IN HUNGARIAN LITERATURE AFTER 1989
Authors: SZÁZ Pavol
Published: October 2023

The present study is an overview of the reception of literary Hasidism and its impact on Hungarian literature after 1989. Even at the end of the 1980s, traces of the anamnesis of the Jewish and Hasidic heritage of rural Eastern Hungary can be discerned in literature and public discourse. In fact, we can speak of the reception of literary Hasidism after the end of the fall of the regime and the tabuization of Jewish topics. Indeed, publishing the Hungarian translation of Martin Buber’s (1995) and Jiří Langer’s (2000) collection of Hasidic stories has influenced several works of fiction. Géza Röhrig’s prose poetics of his “imaginary Hasidic stories” resemble those of the magical realism, with their traditional mixture of imitation and imaginary elements. Langer and other Hasidic story collections inspired some dramatic works in the years following the millennium, notably the plays of Péter Kárpáti, Martin Boross and Szilárd Borbély. Szilárd Borbély’s case is special for our study, as he incorporates Hasidic motifs and reminiscences in several of his works, but mixes them with Christian elements, creating a specific, culturally hybrid bricolage-poetics.
University Students’ Techno-Panic: What Learning Support is Available?
Authors: Manu Jacob , Akyina Kwadwo Oteng
Published: October 2023

The current study sought to identify the level of support provided for first year university students during the novel COVID-19 pandemic online classes with the Moodle learning management system (LMS). The researchers surveyed 1416 first year university students in the second semester of the 2019/2020 academic year, who were all supposed to be part of the web-based courses to logically bring the semester to an end. In an attempt to make students become familiar with the use of the Moodle LMS, the university introduced measures like online orientation, creation of instructional videos, provision of hot phone contact lines as well as IT centre support. Out of these interventions rolled-out by the university, the researchers found that the students did not gain the required benefits as envisaged by the University and for that matter affected the students adversely. From an instructional standpoint, the measures put in place to familiarize students with the Moodle system were laudable. However, the support services provided had issues of implementation. A need exists for a more comprehensive and coordinated support services to adequately equip university students to participate meaningfully in web-based learning.
Attitude Towards English and Frequency of Code Switching: Implications on Grade 10 Students’ English Academic Performance
Authors: Maed Judy M. Saligumba , Barcelona Kriscentti Exzur P.
Published: October 2023

The relationship between code-switching, attitude towards English, and students’ academic performance is complex and context-dependent. To address this, the current study employed a concurrent nested mixed-method approach and investigated the relationship between Grade 10 students' attitudes towards the English language, frequency of code-switching, and academic performance. Sixty students participated in the quantitative portion, and five students took part in a focus group discussion for the qualitative portion. Data were collected using an adapted version of Bernice Anoykes’ questionnaire on Attitudes and Motivation and were analyzed using descriptive statistics and regression analysis. The qualitative responses of the participants were analyzed and organized into categories and themes. Results showed that the students had a moderately favorable attitude towards the English language, a high frequency of code-switching, and were approaching a proficient level in their English academic performance. The study also found that attitudes towards English and the frequency of code-switching significantly influenced their academic performance in English. Remarkably, the participants perceived their attitude towards the English language as a hindrance to learning, expressing apprehension about potential embarrassment and language anxiety. Conversely, they also regarded it as an avenue for career advancement, recognizing its potential for employment opportunities, access to knowledge, and the development of academic literacy. These findings offer important information for teachers and language learners, emphasizing the impact of attitudes towards the English and code-switching on academic achievement. The study suggests that educators promote positive attitudes, authentic language practice, and targeted instruction to enhance language learners’ proficiency and academic success in English.
Realidades de la Industria del Cannabis Medicinal en el Contexto Rural Integral Colombiano
Authors: Bustamante Matoma Harold Anderson , Murillo Ortega Vladimir , Martinez Cruz Greicy Katherine , Sanchez Mendez Natali , Agudelo Ruiz Jairo Alberto
Published: October 2023

El objetivo central de la presente investigación es reconocer las realidades de la industria del cannabis medicinal en el contexto del desarrollo rural integral colombiano evidenciando las facilidades y dificultades que presenta la industria cannábica durante toda la cadena logística y productiva para contribuir en el desarrollo de avances para la economía local frente a las adversidades y el dolor de múltiples enfermedades crónicas, siendo este ampliamente utilizado a nivel internacional con fines recreativos y de uso terapéutico (Rojas et al 2019). Dicha investigación se justifica desde el potencial de consumo que ha venido presentando generando avances en la construcción de propuestas en marcos regulatorios por diversos países presentando una alta demanda para la generación de oportunidades de negocio, la metodología desarrollada fue de enfoque cuantitativo, de tipo descriptivo, lo cual permite enfatizar a profundidad los paradigmas propios del sujeto de estudio para la obtención de resultados sólidos y confiables (Guerrero 2022). La población objeto de estudio correspondió a cultivadores, productores y distribuidores del cannabis medicinal en el territorio nacional, con una muestra de (67) participantes, finalmente se exponen los beneficios y dificultades de la industria mediante el diseño y validación del instrumento INOPO ECCI, se concluye los avances significativos para la integración rural integral.
Prevalencia de la Miocardiopatía Dilatada en Deportistas de Alto Rendimiento
Authors: Diaz Diaz Jose Luis , Brito Jacome Carlos José , Lalinde Ruiz Juan Camilo , Rodríguez Arevalo Laura Johana , Buendia Gomez Andres Fernando , Almaza Romero Jorge Andres , Peralta Farak Juan Carlos , Maury Ayala Andrés Alberto
Published: October 2023

La miocardiopatia dilatada (MCD) es una patología que afecta al miocardio y se caracteriza por una dilatación  miocárdica, donde este músculo se estira más de lo normal dando paso a un adelgazamiento de las fibras y por ende, las cavidades cardiacas se vuelven más grandes. Tiene una prevalencia de 1 \ 2,500 a nivel mundial, presentando síntomas tales como dolor torácico, desmayo, debilidad, etc. En los deportistas de alto rendimiento, es de gran importancia la realización de diferentes estudios como un EKG de 12 de derivaciones que permita observar las alteraciones presentes en dicha patología ya que los deportistas tienen un riesgo de muerte súbita cardiaca en relación con la presencia de dicha patología. Por ello, realizamos una búsqueda bibliográfica con diferentes descriptores dándonos como resultados diferentes reportes de casos en los que se evidencian la presencia de miocardiopatía dilatada en deportistas que realizan diferentes disciplinas. Por lo que podemos concluir que la detección temprana de esta patología permite mejorar la calidad de vida y el bienestar de los deportistas.
The Effect of Blade Distances on the Performance of Double-Stage Gravitational Water Vortex Turbine
Authors: Danieal Aderson Sinaga  , Muhamad Dwi Septiyanto  , Zainal Arifin  , Gunawan Rusdiyanto  , Singgih Dwi Prasetyo  , Syamsul Hadi
Published: October 2023

A gravitational water vortex turbine is a turbine that generates electricity by rotating its runner under vortex flow through basins. The present experimental study investigated the effect of blade distance through a double-stage vortex turbine. The study used rotational speeds, torque, and efficiency to describe the vortex turbine performance under different applied discharges and blade distances. Each blade has a different profile, such as Savonius and a curved blade profile. Each blade independently generates its performance because they constructed under different hollow and solid shafts. The results illustrated that an increased distance between blades produces the best performance with a higher flow rate. A discharge of 9.5×10-3m3/s and a distance of 150 mm has a total mechanical power of 28,51 W with an efficiency of 28.92%. The longest distance between the stage 1 (S1) and stage 2 (S2) turbine causes the smaller air core diameter. It has given an advantage in their performances on rotational speeds, mechanical power, torque, and efficiency generated by the Gravitational Water Vortex Turbine (GWVT).
An Analysis of Music and Politics: The Ghanaian Instance
Authors: Amparbin Ernest Francis , Owusu-Baah Emmanuel
Published: October 2023

This piece aimed to analyze the use of music and its related activities in politics, particularly Ghanaian politics to effectively impact the organization of activities in the areas of party formation, rallies and electioneering campaigns. The authors opined that through music, leaders and organizers of political parties are able to better communicate to the public to attract winning sympathy. The authors employed participatory observation and unstructured interviews to gather primary data from five political parties including the two main parties (National Democratic Congress and New Patriotic Party). The findings indicate that music and related performances are instrumental in bringing party members together, attracting new members to fold, and forming formidable parties. The authors recommend that the leadership of political parties should organize and encourage regular musical activities between members and the party as a whole.

Keywords: Political Anthems, Electioneering Campaigns, Political Parties, Party Politics, Music Related Activities.
AN INNOVATION PLACE MODEL FOR THE ANALYSIS OF CREATIVITY AND SOCIAL INNOVATIVENESS IN SELECTED FRENCH AND POLISH METROPOLISES
Authors: Bierwiaczonek Krzysztof , Pyka Robert
Published: October 2023

The article’s starting point is the assumption that, because of their socio-cultural and economic diversity, density, and complexity of interaction systems, metropolises provide a sufficient basis for creating innovation – including social innovation emerging from residents’ grassroots activities. Such perspective emphasises the importance of the creative potential of residents, as materialised in emerging innovation places and collectives operating and dispersed throughout the city. Assuming such a perspective made it possible to build an original model for this study of an innovation place that combines the features of classical and dynamic theories of place. In the empirical portion of the article, the data obtained during the study of ten selected innovation places located in three European metropolises are analysed. The study used qualitative methodology: in-depth interviews and observations. The study’s main objective was to assess the utility of the model of the innovation place as a tool for identifying and analysing metropolitan social innovation. This objective has been achieved, and the data obtained showed that, by using the model with characteristics typical of an innovation place, it is possible to effectively analyse the process of creating social innovation, indicate its determinants, and reveal differences in the innovation places under study.
A New Scenario of Solar Modulation Model during the Polarity Reversing
Authors: Jiang Jieteng , Lin Sujie , Yang Lili
Published: October 2023

When entering the heliosphere, galactic cosmic rays (GCRs) will encounter the solar wind plasma, reducing their intensity. This solar modulation effect is strongly affected by the structure of the solar wind and the heliospheric magnetic field (HMF). To address the effect during the solar maximum of cycle 24, we study the solar modulation under a scenario in which the weights for A = ±1 are determined by the structure of HMF, and the traveling time of GCRs simulated by SOLARPROP is taken into account. We then fit the cosmic-ray proton data provided by AMS-02 and Voyager in the energy range 4 MeV–30 GeV, and confirm that the modulation time lag in this model is about 9 months, which is consistent with the previous studies. This model incorporates a more realistic description of the polarity reversing and provides a more reliable estimation of the solar modulation effect during the maximum activity period.
Evolution of a Water-rich Atmosphere Formed by a Giant Impact on an Earth-sized Planet
Authors: Kurosaki Kenji , Hori Yasunori , Ogihara Masahiro , Kunitomo Masanobu
Published: October 2023

The atmosphere of a terrestrial planet that is replenished with secondary gases should have accumulated hydrogen-rich gas from its protoplanetary disk. Although a giant impact blows off a large fraction of the primordial atmosphere of a terrestrial planet in the late formation stage, the remaining atmosphere can become water-rich via chemical reactions between hydrogen and vaporized core material. We find that a water-rich postimpact atmosphere forms when a basaltic or CI chondrite core is assumed. In contrast, little postimpact water is generated for an enstatite chondrite core. We investigate the X-ray- and UV-driven mass loss from an Earth-mass planet with an impact-induced multicomponent H2–He–H2O atmosphere for Gyr. We show that water is left in the atmosphere of an Earth-mass planet when the low flux of escaping hydrogen cannot drag water upward via collisions. For a water-dominated atmosphere to form, the atmospheric mass fraction of an Earth-mass planet with an oxidizing core after a giant impact must be less than a few times 0.1%. We also find that Earth-mass planets with water-dominated atmospheres can exist at semimajor axes ranging from a few times 0.1 au to a few au around a Sun-like star, depending on the mass-loss efficiency. Such planets are important targets for atmospheric characterization in the era of JWST. Our results indicate that efficient mixing between hydrogen and rocky components during giant impacts can play a role in the production of water in an Earth-mass planet.
Photometry of Outer Solar System Objects from the Dark Energy Survey. I. Photometric Methods, Light-curve Distributions, and Trans-Neptunian Binaries
Authors: Bernardinelli Pedro H. , Bernstein Gary M. , Jindal Nicholas , Abbott T. M. C. , Aguena M. , Alves O. , Andrade-Oliveira F. , Annis J. , Bacon D. , Bertin E. , Brooks D. , Burke D. L. , Carnero Rosell A. , Carrasco Kind M. , Carretero J. , da Costa L. N. , Pereira M. E. S. , Davis T. M. , Desai S. , Diehl H. T. , Doel P. , Everett S. , Ferrero I. , Friedel D. , Frieman J. , García-Bellido J. , Giannini G. , Gruen D. , Herner K. , Hinton S. R. , Hollowood D. L. , Honscheid K. , James D. J. , Kuehn K. , Marshall J. L. , Mena-Fernández J. , Menanteau F. , Miquel R. , Ogando R. L. C. , Palmese A. , Pieres A. , Plazas Malagón A. A. , Raveri M. , Sanchez E. , Sevilla-Noarbe I. , Smith M. , Suchyta E. , Swanson M. E. C. , Tarle G. , To C. , Walker A. R. , Wiseman P. , Zhang Y. ,   (The DES Collaboration)
Published: October 2023

We report the methods of and initial scientific inferences from the extraction of precision photometric information for the >800 trans-Neptunian objects (TNOs) discovered in the images of the Dark Energy Survey (DES). Scene-modeling photometry is used to obtain shot-noise-limited flux measures for each exposure of each TNO, with background sources subtracted. Comparison of double-source fits to the pixel data with single-source fits are used to identify and characterize two binary TNO systems. A Markov Chain Monte Carlo method samples the joint likelihood of the intrinsic colors of each source as well as the amplitude of its flux variation, given the time series of multiband flux measurements and their uncertainties. A catalog of these colors and light-curve amplitudes A is included with this publication. We show how to assign a likelihood to the distribution q(A) of light-curve amplitudes in any subpopulation. Using this method, we find decisive evidence (i.e., evidence ratio <0.01) that cold classical (CC) TNOs with absolute magnitude 6 < H

r
< 8.2 are more variable than the hot classical (HC) population of the same H

r
, reinforcing theories that the former form in situ and the latter arise from a different physical population. Resonant and scattering TNOs in this H

r
range have variability consistent with either the HCs or CCs. DES TNOs with H

r
< 6 are seen to be decisively less variable than higher-H

r
members of any dynamical group, as expected. More surprising is that detached TNOs are decisively less variable than scattering TNOs, which requires them to have distinct source regions or some subsequent differential processing.
Deep Synoptic Array Science: Implications of Faraday Rotation Measures of Fast Radio Bursts Localized to Host Galaxies
Authors: Sherman Myles B. , Connor Liam , Ravi Vikram , Law Casey , Chen Ge , Sharma Kritti , Catha Morgan , Faber Jakob T. , Hallinan Gregg , Harnach Charlie , Hellbourg Greg , Hobbs Rick , Hodge David , Hodges Mark , Lamb James W. , Rasmussen Paul , Shi Jun , Simard Dana , Somalwar Jean , Squillace Reynier , Weinreb Sander , Woody David P. , Yadlapalli Nitika ,   The Deep Synoptic Array Team
Published: October 2023

Faraday rotation measures (RMs) of fast radio bursts (FRBs) offer the prospect of directly measuring extragalactic magnetic fields. We present an analysis of the RMs of 10 as yet nonrepeating FRBs detected and localized to host galaxies with robust redshift measurements by the 63-antenna prototype of the Deep Synoptic Array (DSA-110). We combine this sample with published RMs of 15 localized FRBs, nine of which are repeating sources. For each FRB in the combined sample, we estimate the host-galaxy dispersion measure (DM) contributions and extragalactic RM. We find compelling evidence that the extragalactic components of FRB RMs are often dominated by contributions from the host-galaxy interstellar medium (ISM). Specifically, we find that both repeating and as yet nonrepeating FRBs show a correlation between the host DM and host RM in the rest frame, and we find an anticorrelation between extragalactic RM (in the observer frame) and redshift for nonrepeaters, as expected if the magnetized plasma is in the host galaxy. Important exceptions to the ISM origin include a dense, magnetized circumburst medium in some repeating FRBs, and the intracluster medium of host or intervening galaxy clusters. We find that the estimated ISM magnetic-field strengths,

B

¯

∣
∣

, are characteristically ∼1–2 μG larger than those inferred from Galactic radio pulsars. This suggests either increased ISM magnetization in FRB hosts in comparison with the Milky Way, or that FRBs preferentially reside in regions of increased magnetic-field strength within their hosts.
Viral-induced inflammation can lead to adverse pregnancy outcomes
Authors: Papadatou Vasiliki , Tologkos Stylianos , Deftereou Theodora , Alexiadis Triantafyllos , Pagonopoulou Olga , Alexiadi Christina-Angelika , Bakatselou Panagiota , Oglou Sadik Tzem Chousein , Tripsianis Grigorios , Mitrakas Achilleas , Lambropoulou Maria
Published: October 2023

Introduction: Parvoviruses are DNA viruses of small size. There have been a number of reports indicating the possible effects of B19 infections during pregnancy. These effects include spontaneous abortions, stillbirth, fetal damage, and quite often, fetal anemia with hydrops fetalis.

Aim: The aim of this study was the correlation of Epstein-Barr virus (EBV) and parvovirus-B19 infections with inflammation levels in placental tissue coming from spontaneous abortions and elective terminations cases. We also investigated whether viral presence could cause spontaneous abortions by associating the expression levels of inflammatory markers with adverse pregnancy outcomes.

Materials and methods: One hundred ninety-four placental samples were used, 152 included in the study group coming from spontaneous abortions while 42 controls were used from cases of elective terminations. Hematoxylin and eosin (H&E) staining was performed to investigate morphological changes in the tissues, and then indirect immunohistochemistry to evaluate the expression of TNF-α, IL-6, IL-1α, B19, and EBV. Statistical analysis was performed using SPSS v. 19.0 (IBM).

Results: Higher inflammation levels were observed with statistical significance in the spontaneous abortions group (p<0.001) and they were correlated with statistical significance with B19 or EBV presence (p<0.001). Viral presence was only found in the spontaneous abortions group. Both simple and multiple logistic regression confirmed that viral presence was an independent prognostic factor for high expression of all inflammatory biomarkers with statistical significance (p<0.001).

Conclusions: Our results clearly indicate a specific pattern. Viral presence can deregulate inflammatory processes in the maternal-fetal environment and thus work as a trigger for spontaneous abortions.
A rare case of recurrent mediastinal malignant paraganglioma of thyroid origin: a case report
Authors: Yankov Georgi , Alexieva Magdalena , Ivanova Silvia , Yanev Nikolay
Published: October 2023

Paraganglioma is a neuroendocrine tumor that originates from extraadrenal chromaffin cells. Primary thyroid paraganglioma is an extremely rare neoplasm. In this study, an exceptionally uncommon case of recurrent mediastinal malignant paraganglioma with primary origin from thyroid gland is presented. Median resternotomy, resection of left brachiocephalic vein, and extirpation of the mediastinal tumor were performed successfully. Commonly, it is preoperatively misdiagnosed and has unpredictable biological behavior. Incorrect diagnosis results in disastrous consequences for the patient, and consequently, correct pre- and postoperative diagnoses promise an optimal treatment plan and good prognosis. Long-term follow-up is indicated in all patients due to the risk of recurrence and distant metastases.
Socket preservation using a combination of propolis extract and bovine bone graft towards the expression of receptor activator of nuclear κB ligand and osteoprogerin
Authors: Kresnoadi Utari , Sari Nila , Laksono Harry
Published: October 2023

Aim: This study was undertaken to comprehend the effect of a combination of bovine bone graft (BBG) and propolis extract on the receptor activator of nuclear κB ligand (RANKL) and osteoprotegerin (OPG) expressions in post-extraction tooth sockets.

Materials and methods: Fifty-six male Cavia Cobayas were divided into eight groups each containing seven subjects. The lower left incisor of each subject was removed prior to four different materials - polyethylene glycol (PEG), propolis extract+PEG, BBG+PEG, and propolis extract+BBG+PEG (combination) being applied to the post-extraction sockets. The laboratory animals were sacrificed at three and seven days. An immunohistochemical examination was subsequently performed to observe the expression of RANKL and OPG using a light microscope at 1000× magnification.

Results: The mean expression of RANKL on the third and seventh days was the lowest in the combination group, while the mean OPG expression on those days was the highest in the combination group. The one-way ANOVA tests conducted on each group produced a p value <0.05 indicating that significant differences existed between certain groups. A Pearson’s correlation test conducted on both observation day groups highlighted the opposite correlation of RANKL and OPG.

Conclusions: A combination of propolis extract and BBG effectively upregulates OPG expression and downregulates RANKL expression in the preserved post-extraction socket.
La photographie sous toutes ses coutures dans un collectif de recherche-création. Entretien avec le collectif CRAVAT.
Authors: Bonaccorsi Julia , Bonnet Estelle , Desaleux David , Drouet Jeanne , Mazuyer Emmanuelle
Published: October 2023

Par cet entretien réalisé en 2021 avec le Collectif de Recherche Autour du Vêtement Au Travail (CRAVAT), il s’agit d’explorer la place fondatrice et centrale de la photographie dans son projet, place incarnée par un professionnel photographe qui est membre du projet à part entière. L’échange avec quatre membres de l’équipe rend compte des ajustements concernant le statut de l’image photographique, souligne les préconceptions et révèle des liens sensibles et inattendus entre les disciplines. La réflexivité permise par l’entretien dévoile ainsi une pluralité de positions interprétatives sur la photographie, que la conception d’une exposition à l’issue du projet permet de stabiliser.
L’heure zéro . Mythe, déréalisation, fondation
Authors: Kahn Laurence
Published: October 2023

Même si la sublimation ressortit à un jugement de valeur dont Freud a fait l’un des étais de sa définition, l’assimilation du travail à l’activité artistique – placé au cœur du mythe national-socialiste – tout comme le rôle joué par « l’art de la politique » exigent que l’on interroge la performativité culturelle du mythe aryen et son pouvoir utopique, puis que l’on questionne le processus collectif qui conduisit la communauté allemande à « déréaliser » la dévastation et les pertes, au bénéfice d’une reconstruction quasi maniaque. Comment la haine cimenta-t‑elle la collectivité en emboîtant les revendications de la pulsion d’auto-conservation individuelle dans la promesse d’un Lebensraum supposé garantir l’auto-conservation du groupe ? À l’inverse, quel sens attribuer à L’homme Moïse à l’heure où la « déjudaïsation » du droit tentait d’éradiquer la rationalité abstraite de la loi juive et sa fonction sublimatoire ? Enfin grâce à quelle conflictualisation la société allemande parvint-elle à surmonter le silence qui s’était abattu sur l’histoire à « l’heure zéro » ?
« Passions et destins des passions » : Quelle(s) issue(s) sublimatoire(s) ?
Authors: Maurice Claire
Published: October 2023

Lorsque la passion passe au premier plan de la scène analytique, elle tend à brouiller les frontières entre l’idéalisation et la sublimation. Comment, dès lors, dans ces contextes où la problématique de l’idéal devient centrale au sein de la cure, tenter de dégager un ou des processus sublimatoire(s) ? Si la sublimation reste un changement de but sexuel, elle interroge la manière d’y parvenir à partir du détour par l’objet, par sa rencontre comme par son deuil. C’est à ce paradoxe que nous confronte la cure de Julien, entre idéalisation et haine de l’objet.
Nécessité et insuffisance des sublimations
Authors: Chervet Emmanuelle
Published: October 2023

L’auteure discute l’idée de Laurent Danon-Boileau d’une origine de la sublimation liée à un manque de représentations inconscientes qui exige le traitement de l’excitation traumatique en excès. Elle propose d’introduire aussi le rôle du surmoi pour permettre l’aboutissement de la sublimation, processus actif qui passe par la trouvaille d’un objet du monde à transformer. C’est de l’articulation de la sublimation à l’identification que dépend sa valeur élaborative pour la psyché. Une vignette clinique illustre le fait qu’une rupture dans la sublimation ouvre à l’élaboration d’un pan de l’histoire qu’elle occultait. Quelques précisions sont proposées sur la différenciation entre sublimations « ordinaires » et sublimations « d’exception ».
Contradictions dans la sublimation 1923-2023
Authors: Richard François
Published: October 2023

Cet article cherche à montrer, à partir d’une lecture serrée de Le moi et le ça, l’actualité de l’hypothèse freudienne de 1923 sur la sublimation intrinsèquement contradictoire, entre réussite d’une opération de transformation salvatrice de la libido et risque corollaire de déliaison entre Éros et pulsion de mort. Il souligne la grande différence entre la définition précise de la sublimation comme métamorphose du polymorphisme sexuel infantile en polymorphisme artistique et littéraire, et sa définition comme simple désexualisation, laquelle évolue facilement en désublimation dépressive. Lorsque le refoulement ne suffit plus, un clivage apparaît, on tient peut-être là un état limite de la névrose : on peut faire l’hypothèse qu’une vague hallucinatoire menace le moi et appelle un recours à la sublimation comme solution d’urgence. Clivage ou sublimation, telle est alors la question. Des exemples littéraires classiques (Hugo, Breton, Aragon, Gracq) illustrent cette hypothèse – laquelle éclaire aussi les antisublimations modernes, en particulier certaines tendances de l’art contemporain et des contre-cultures adolescentes, pour lesquelles la déliaison est une valeur. D’autres formes de création suggèrent des issues plus positives, où la contradiction entre les pulsions et l’esthétique du sublime est moins tendue.