bluuebunny/crossref_metadata_2025 huggingface dataset:
Monitoring cotton squares with opened and/or yellowed bracts to determine the need and efficency of chemical control against the cotton boll weevil
Authors: Lima T. A. , Silva C. A. D. , Zanuncio J. C.
Published: May 2024

Abstract The technique of terrestrial sampling of boll weevil (BW) populations is expensive and inefficient over large areas, but may be cheaper and more efficient without involving the manipulation of cotton squares. The aim of this study was to develop a technique to sampling cotton squares based on the observation of opened and/or yellowing bracts to determine the need and efficacy of chemical control of BW in cotton crops. The first experiment aimed to estimate the ratio between the number of cotton squares with opened and/or yellowed bracts and that of squares with BW oviposition punctures. The second experiment, aimed to determine the efficacy of chemical control for BW by sampling cotton squares with opened and/or yellowed bracts. The ratio between the number of opened and/or yellowed bracts and the number of cotton squares with oviposition punctures was 2:1. The level and efficiency of chemical control of BW, based on the percentage and sampling of cotton plants with opened and/or yellowed bracts, was 5% and did not differ from the one based on the observation of cotton plants with 10% cotton squares with oviposition punctures by BW females. The control level based on sampling cotton plants with open and/or yellowing bracts was 5%. The efficiency of chemical insecticides using this economic threshold against the BW did not differ from that based on sampling cotton plants with 10% of cotton squares with oviposition punctures by BW females. This indicates that the chemical control of cotton boll weevil can be carried out based on cotton squares with open and/or yellowed bracts.
Anti-Pythium insidiosum intradermal immunotherapy in horses: diagnosis and therapy
Authors: Santos Carlos E.P. , Loreto Erico S. , Zanette Régis A. , Bortolini Juliano , Santurio Janio M. , Marques Luis C.
Published: May 2024

ABSTRACT: Pythiosis is a life-threatening disease that affects various species and is prevalent in regions with high humidity. The ailment is increasingly reported globally, and in Brazil, it is an important cause of profound economic and health losses in equines. This study aimed to explore the potential of intradermal immunotherapy as both a diagnostic and therapeutic approach for pythiosis in horses from the Pantanal region of Mato Grosso, Brazil. The horses were divided into three groups: those never diagnosed with pythiosis or with lesions that could be mistaken for pythiosis (Group 1); previously infected but successfully treated horses (Group 2); and horses with a positive diagnosis for pythiosis that were under treatment (Group 3). An immunotherapeutic product (PitiumVac®) was administered intradermally. Injection site reaction and response to immunotherapy were assessed. The results indicated that intradermal immunotherapy could be a viable diagnostic and therapeutic tool, particularly in remote areas where traditional laboratory diagnosis methods are not readily accessible. The efficacy of intradermal administration was comparable to that of subcutaneous administration in treating pythiosis in horses, and the combined use of immunotherapy and triamcinolone acetonide yielded promising results for treating pythiosis in horses. However, further research is required to validate these findings. This study contributes to understanding and managing pythiosis more efficiently by providing a simple, cost-effective, and potentially efficient alternative approach to diagnosis and treatment.
Cutaneous diseases diagnosed in cattle in southern Brazil from 2000 to 2022
Authors: Venancio Fabiano R. , Alberti Taina S. , Engelmann Thais M. , Sallis Eliza Simone V. , Schild Ana Lucia
Published: May 2024

ABSTRACT: A retrospective study of skin diseases diagnosed in cattle from 2000 to 2022 was performed at the “Laboratório Regional de Diagnóstico” of the “Faculdade de Veterinária” of the “Universidade Federal de Pelotas” (LRD-UFPel) to determine the main skin diseases that affect cattle in southern Brazil. Information regarding epidemiological data, lesions and diagnosis was collected. The diseases were grouped into infectious/inflammatory, toxic, nonneoplastic proliferative and neoplastic. The macroscopic aspects, distribution, histopathology, and evolution of the lesions were obtained in the protocols, and the original diagnosis was preserved. The main skin diseases diagnosed during this period occurred during outbreaks. They were infectious, with an emphasis on dermatophilosis, papillomatosis and dermatophytosis, followed by hepatogenous photosensitization, which was included in the group of toxic diseases. Among the neoplasms, squamous cell carcinoma stood out, occurring in isolated cases, reflecting an irrelevant cause of economic losses.
VALIDATION OF AN ONLINE COURSE ON POSTURAL CARE FOR PRETERM NEWBORNS
Authors: Brandão Neto Waldemar , Silva Dayane Gabrielly da , Araújo Nicolle Augusta Artoni de Brito , Souza Claudinalle Farias Queiroz de , Cunha Eunice de Fátima Soares da , Moura Talita Helena Monteiro de , Furtado Maria Cândida de Carvalho
Published: May 2024

ABSTRACT Objectives: Validation of an online course content on postural care for newborns in the Neonatal Intensive Care Unit and assessment of participant satisfaction. Method: Methodological study of content validation by 13 judges with expertise in neonatology and online education who responded to the educational content validation instrument, and by 175 course participants who evaluated the course through a satisfaction questionnaire. The criterion for validation was agreement above 80.0%, analyzed through the Content Validity Index (CVI), Content Validation Coefficient (CVC), binomial test, and descriptive statistics for analyzing satisfaction variables. Data collection took place from January to June 2022 for the validation stage, and during June 2023 for the evaluation stage conducted by the course participants. Results: All items obtained agreement above 80.0% with a total CVI and CVC of 83.3% and 91.0%, respectively. The course participants positively evaluated the course regarding content organization, coherence between theory and practice, navigability, quality of materials, and applicability in professional practice. Conclusion: The online course was considered valid regarding its objectives, structure/presentation, and relevance. Therefore, it can be offered as an open educational resource in the training of healthcare and nursing professionals to provide postural care to newborns in critical environments, thereby enhancing the performance of developmental care.
NURSES’ PERSPECTIVES ON THE USE OF MOBILE APPLICATIONS FOR SELF-CARE IN CHRONIC ILLNESSES
Authors: Carvalho Simone Mendes , Sousa Maria Rui Miranda Grilo Correia de
Published: May 2024

ABSTRACT Objective: to analyze the nurses’ perspective on the possibility of incorporating the use of mobile applications into their care practice as a strategy for promoting self-care in people with chronic diseases. Method: an exploratory-descriptive study with a qualitative approach. Data were collected between the months of February and March 2023 with 10 nurses who were Master’s degree students in Community Nursing in the Family Health Nursing area from a higher education institution in Nursing in Portugal. The data were analyzed using the content analysis technique proposed by Bardin. The MAXQDA software program was used to facilitate and accelerate qualitative data analysis through coding and categorization. Results: the results were organized into two main categories: challenges for managing the therapeutic regimen and self-care; and strategies for promoting self-care in chronic diseases from the perspective of nurses. The challenges during the Covid-19 pandemic generated elements which hinder and facilitate management of the therapeutic regimen and self-care in people with chronic diseases. From the nurses’ perspective, the use of mobile applications can facilitate promoting self-care in people with chronic illnesses. Conclusion: chronic disease control heavily depends on people’s behaviors and self-management of the disease. The nurses in this study considered that the use of mobile applications can help both healthcare professionals and people with chronic illnesses in promoting health and in the self-care process.
Maquinical Ensembles in Fugue: feminisms and performativity in two Andean music groups from Argentina
Authors: Podhajcer Adil , Vega Alejandra
Published: May 2024

ABSTRACT In this article we describe and comparatively analyze the performances of two community Andean music ensembles that represent two regions of Argentina with contrasting characteristics, and that constitute the two most important referents of groups of women and dissidents in Argentina. In this opportunity, we will focus on the performative practices of the women's Band from Tilcara Nuestra Señora de Fátima, Jujuy, and the Mama Quilla Community, from the Buenos Aires Metropolitan Area. The objective is to understand the relationship between the experience-in-the-world understood as a projection oriented towards a cosmogony with Andean roots and the aesthetic-political qualities that reinstate the question of the scope of dissident feminism to produce other modes of action and political consciousness.
Different sources of nutrients in the production and quality of “Veneranda” curly lettuce
Authors: Monteiro Shirley S , Martins Laesio P , Araújo Raunira da C , Silva Elnatan A da , Monteiro Shênia S
Published: May 2024

ABSTRACT Driven by the growing demand for good quality food, agriculture is changing the way of cultivation to attend consumer’s expectations. In addition to the nutritional value, the production system has been an important factor in the consumer’s intention to purchase products. In this scenario, this work aimed to evaluate the effects of different nutrient sources on production characteristics and nutritional quality of 'Veneranda' lettuce. The experiment was conducted in randomized block design, with seven treatments (control, bokashi, organic compost, mineral fertilizer, mineral fertilizer + organic compost, foliar biofertilizer and soil biofertilizer), and five replications. In commercial vegetative stage, lettuce was harvested and evaluated for physical, physicochemical, bioactive compounds and mineral composition. Lettuce produced with mineral and organomineral fertilizers showed the highest yield of physical characteristics, which is related to the highest nitrogen content in their leaves. The use of organomineral fertilization, organic and mineral compost and biofertilizer via leaf application presented a positive effect on lettuce cultivation, with better nutritional quality and productivity.
Role of sanitizers and biostimulants on root and shoot growth and enzyme activity of arracacha propagules
Authors: Santos Leandro dos , Macedo Willian R
Published: May 2024

ABSTRACT Biostimulants are chemical or biological components adopted to improve nutrient uptake/efficiency and tolerance to abiotic stresses in crops. We studied three biostimulants (Stimulate®, tryptophol and Bacillus subtilis C-3102) associated to two sanitizers (sodium hypochlorite or thymol), on initial growth of propagules of Arracacia xanthorrhiza. Sodium hypochlorite associated to B. subtilis improve the leaf gas exchange, furthermore this treatment showed greater root volume. The interaction among sodium hypochlorite and tryptophol improves the plant branching; in addition this association showed better results for root dry mass. Different biostimulants improve differently the arracacha organs development, hence it is necessary to evaluate the plant morphophysiological competence to apply the correct biostimulant and sanitizer.
A emergência do Zika vírus no Brasil e a resposta federal dos Sistemas Nacionais de Vigilância em Saúde e de Vigilância Sanitária
Authors: Oliveira Catia Veronica dos Santos , Pepe Vera Lucia Edais , Reis Lenice Gnocchi da Costa , Albuquerque Mariana Vercesi , Dias Henrique Sant'Anna
Published: May 2024

Resumo O artigo analisa a resposta federal dos Sistemas Nacionais de Vigilância em Saúde e de Vigilância Sanitária frente à epidemia do Zika vírus no Brasil, de 2015 a 2018, com foco nos contextos político-institucionais e no conteúdo das medidas governamentais desenvolvidas no período. O estudo ancorou-se na abordagem institucionalista histórica, compreendendo análise documental e entrevistas com atores-chave. A resposta se caracterizou pela priorização inicial da emergência sanitária na agenda política do governo federal, reduzindo-se ao longo do período, influenciada pelas crises financeira e política. Verificou-se multiplicidade de atores e instâncias voltadas à contingência, com certa articulação entre os dois sistemas, a partir de experiências pré-emergência próprias. O controle vetorial teve centralidade, valorizando ações intersetoriais e comunitárias, induzidas sobretudo pela Secretaria de Vigilância em Saúde do Ministério da Saúde e complementarmente pela Agência Nacional de Vigilância Sanitária. Observaram-se expressivas limitações alocativas de recursos financeiros novos e mudanças no aparato organizativo de resposta, com efeitos para a continuidade das políticas no pós-emergência, incluindo o desenvolvimento de medicamentos, vacinas e testes. A Emergência em Saúde Pública do Zika Vírus no Brasil foi marcada por limitada institucionalização de aprendizados e estratégias estruturantes, reduzindo oportunidades para a (re)organização das vigilâncias no Sistema Único de Saúde.
Send it to one, throw it to another: the Zika health emergency on the margins of the State
Authors: Moreira Martha Cristina Nunes , Oliveira Ellen Hilda Souza de Alcantara , Campos Daniel de Souza , Nascimento Marcos Antonio Ferreira do , Peiter Paulo Cesar
Published: May 2024

Abstract Temporarily distant from the declaration of the Public Health Emergency of International Importance (ESPII) and Public Health Emergency of National Importance (ESPIN) caused by the Zika epidemic, in 2015, we enunciate the legacy of the humanitarian emergency. Based on qualitative research, through focus groups with health professionals and families of children affected by the Zika epidemic in Natal and Feira de Santana, we seek to discuss this public health phenomenon through the lens of State Anthropology. We conclude that the non-recognition of the State as an instance embodied in the daily practices of its local agents leads to the reproduction of discriminatory practices emptied of political sense and the recognition of moralities that permeate the absences in health promotion actions and recognition strategies, and search for methods to guarantee the right to health.
Manda pra um, joga pra outro: a emergência sanitária da zika nas margens do Estado
Authors: Moreira Martha Cristina Nunes , Oliveira Ellen Hilda Souza de Alcantara , Campos Daniel de Souza , Nascimento Marcos Antonio Ferreira do , Peiter Paulo Cesar
Published: May 2024

Resumo Distantes temporalmente da declaração da emergência em saúde pública de importância internacional (ESPII) e emergência em saúde pública de importância nacional (ESPIN) provocada pela epidemia de zika, no ano de 2015, enunciamos a herança da emergência humanitária. Com base em uma pesquisa qualitativa, por meio de grupos focais realizados com profissionais de saúde e familiares das crianças afetadas epidemia de zika em Natal e Feira de Santana, buscamos discutir esse fenômeno de saúde pública pelas lentes da Antropologia do Estado. Concluímos que o não reconhecimento do Estado como uma instância encarnada no cotidiano das práticas por parte dos seus agentes locais leva à reprodução de práticas discriminatórias esvaziadas de sentido político e do reconhecimento de moralidades que permeiam as ausências nas ações de promoção de saúde e estratégias de reconhecimento e busca por estratégias para a garantia do direito à saúde.
mTORc2 in Distal Convoluted Tubule and Renal K+ Excretion during High Dietary K+ Intake
Authors: Duan Xin-Peng , Zheng Jun-Ya , Jiang Shao-Peng , Wang Ming-Xiao , Zhang Chengbiao , Chowdhury Tanzina , Wang Wen-Hui , Lin Dao-Hong
Published: May 2024

Key Points

High K stimulates mechanistic target of rapamycin complex 2 (mTORc2) in the distal convoluted tubule (DCT).

Inhibition of mTORc2 decreased the basolateral Kir4.1/Kir5.1 and Na-Cl cotransporter in the DCT.

Inhibition of mTORc2 of the DCT compromised kidneys' ability to excrete potassium during high K intake.

Background

Renal mechanistic target of rapamycin complex 2 (mTORc2) plays a role in regulating renal K+ excretion (renal-EK) and K+ homeostasis. Inhibition of renal mTORc2 causes hyperkalemia due to suppressing epithelial Na+ channel and renal outer medullary K+ (Kir1.1) in the collecting duct. We now explore whether mTORc2 of distal convoluted tubules (DCTs) regulates basolateral Kir4.1/Kir5.1, Na-Cl cotransporter (NCC), and renal-EK.

Methods

We used patch-clamp technique to examine basolateral Kir4.1/Kir5.1 in early DCT, immunoblotting, and immunofluorescence to examine NCC expression and in vivo measurement of urinary K+ excretion to determine baseline renal-EK in mice treated with an mTORc2 inhibitor and in DCT-specific rapamycin-insensitive companion of mTOR knockout (DCT-RICTOR-KO) mice.

Results

Inhibition of mTORc2 with AZD8055 abolished high-K+–induced inhibition of Kir4.1/Kir5.1 in DCT, high potassium–induced depolarization of the DCT membrane, and high potassium–induced suppression of phosphorylated Na-Cl cotransporter (pNCC) expression. AZD8055 stimulated the 40-pS inwardly rectifying K+ channel (Kir4.1/Kir5.1-heterotetramer) in early DCT in the mice on overnight high potassium intake; this effect was absent in the presence of protein kinase C inhibitors, which also stimulated Kir4.1/Kir5.1. AZD8055 treatment decreased renal-EK in animals on overnight high-potassium diet. Deletion of RICTOR in the DCT increased the Kir4.1/Kir5.1-mediated K+ currents, hyperpolarized the DCT membrane, and increased the expression of pWNK4 and pNCC. Renal-EK was lower and plasma K+ was higher in DCT-RICTOR-KO mice than corresponding control mice. In addition, overnight high-potassium diet did not inhibit Kir4.1/Kir5.1 activity in the DCT and failed to inhibit the expression of pNCC in DCT-RICTOR-KO mice. Overnight high potassium intake stimulated renal-EK in control mice, but this effect was attenuated in DCT-RICTOR-KO mice. Thus, overnight high potassium intake induced hyperkalemia in DCT-RICTOR-KO mice but not in control mice.

Conclusions

mTORc2 of the DCT inhibits Kir4.1/Kir5.1 activity and NCC expression and stimulates renal-EK during high potassium intake.
El rumor de los paradigmas: Escritos sobre filosofía de la investigación
Authors: Gómez Marín Raúl Antonio
Published: May 2024

En un singular juego entre el “quehacer investigativo”, la filosofía de la ciencia y la epistemología, El rumor de los paradigmas se inserta activa y propositivamente en la querella contemporánea sobre la investigación y, muy particularmente, en el conflicto de interpretaciones que bordea las fronteras de las ciencias humanas y sociales con temas que nunca dejarán de inquietarnos: la interpretación, la comprensión y el sujeto, los paradigmas, los roles que juegan las hipótesis, el marco epistemológico y la investigación misma, tipificada como un complejo proceso de recursos investigativos. Este libro propone una serie de escritos a manera de capítulos; textos que se enfocan en análisis críticos de diversos aspectos que, a juicio del autor, son cruciales en cualquier investigación. A partir de ahora, quedan para la consideración de profesores y estudiantes universitarios.
Protocol preparation of bacterial cells v1
Authors: Quiroz Monnens Thomas
Published: May 2024

This protocol details the preparation of bacterial cells to set up LSBA.
DNA Extraction -Qiagen BioSprint® 96 Workstation using the Biosprint 96 tissue protocol UIBK eWHALE v1
Authors: Rodriguez Lauren , Thalinger Bettina
Published: May 2024

This DNA extraction protocol is used in Rodriguez et al., 2024 (in prep) for the extraction of environmental DNA from samples collected in the North-East Atlantic and Mediterranean Sea as a part of the eWHALE project. The protocol outlines lysis from both Sylphium (https://sylphium.com/eng/) and Smith-Root (https://www.smith-root.com/) eDNA filters and DNA extraction of lysates using the Qiagen BioSprint® 96 Workstation automated extraction robot + BioSprint 96 DNA blood Kit (ID: 940057). For further information on this protocol, please refer to Qiagen (2012) BioSprint‱ 96 DNA Handbook. Available via Qiagen: https://www.qiagen.com/us/resources/resourcedetail?id=64902c5d-9c3c-4fe3-a3f7-668c4704d9eb&lang=en
Correlation of serum ferritin and thyroid hormone levels: A matched case–control study
Authors: Čano Dedić Lejla , Papić Emsel , Pašalić Arzija , Smajlović Dalila , Šečić – Selimović Sabina , Šegalo Sabina
Published: May 2024

Introduction: Hypothyroidism is a common disorder of the endocrine system caused by insufficient biologically active hormones at the tissue level or the inability of the tissue to utilize thyroid hormones. Iron plays a crucial role in the synthesis and metabolism of thyroid hormones, and it is stored in the body as ferritin. We aimed to evaluate the correlation between serum ferritin (SF) levels and thyroid hormone panel levels in both hypothyroid and euthyroid subjects.
Methods: In 2022, a matched case–control study was conducted. The study involved participants with hypothyroidism and a control group (n = 53). The levels of thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), and SF were measured using the chemiluminescence immunoassay on a Mindray Cl 900-i analyzer (Shenzhen Mindray Bio-Medical Electronics Co., China).
Results: The hypothyroid group had TSH levels that were significantly higher (10.76 [8.54-18.76] vs. 1.76 [1.26-2.58]; p < 0.001) and SF concentrations that were significantly lower (39.08 [21.15-45.70] vs. 54.09 [41.41-71.82]; p < 0.001) compared to the control group. In both male and female subjects of the hypothyroid group, a strong negative correlation was found between SF concentration and TSH levels ([Rho = −0.855,p < 0.01]; [Rho = −0.747; p < 0.01]). In female subjects of the hypothyroid group, a weak positive correlation was found between SF concentration and fT3 (Rho = 0.488; p < 0.05). In the euthyroid group, a correlation of the same strength and direction was found for fT4 (Rho = 0.366; p < 0.05).
Conclusion: Research results indicate a correlation between lower SF concentrations and hypothyroidism, which is of particular importance for understanding the etiopathogenesis, diagnosis, monitoring, and treatment modalities of patients with hypothyroidism.
Retratos lingüísticos de hijos de familias sordas: representaciones de una lengua de herencia signada
Authors:   Universidad Rey Juan Carlos, Papin Stephanie
Published: May 2024

Las personas oyentes de familias sordas, llamadas Children of Deaf Adults (CODA), pueden adquirir su lengua de herencia signada y abrazar su identidad cultural. Sin embargo, la cuestión es cómo logran hacerlo, siendo oyentes en un mundo en el que la invisibilización y la estigmatización de su lengua y cultura familiar son habituales. El objetivo de este artículo es evidenciar cómo se relaciona la construcción identitaria de la persona CODA con la identificación con su lengua y su cultura de herencia. El método de investigación ha seguido un diseño fenomenológico, de tipo interpretativo, con entrevistas semiestructuradas a veintidós personas CODA adultas del Estado español. El estudio revela sus representaciones sobre sus repertorios lingüísticos, mediante los retratos lingüísticos. Las aportaciones de esta investigación abren nuevos interrogantes sobre los propósitos de las lenguas de herencia. El legado lingüístico y cultural de la comunidad sorda, que se ha visto negado en la generación de los padres sordos, puede persistir gracias a la conexión familiar con la lengua y la cultura de herencia en la segunda generación. Esta investigación apoya la conceptualización de la persona hablante de herencia desde un punto de vista cultural y no solamente lingüístico.
Fault detection and isolation using nonlinear observers for emulsion copolimerization processes
Authors: Téllez-Anguiano Adriana del Carmen , Astorga-Zaragoza Carlos Manuel , Reyes-Reyes Juan , Álvarez-Castillo Alberto , Adam-Medina Manuel
Published: May 2024

In this work the design and implementation of a fault detection and isolation system for a process of copolymerization in emulsion are presented. The proposed approach used to design the residual generators is based on decoupling techniques using differential geometry and high gain nonlinear observers; every residue is dedicated to the detection and the location of a particular fault. The faults considered in this work are additive, presented in the actuators of the process and they represent a malfunction in the feeding flow pumps of the monomer towards the interior of the reactor. The observers used to generate residuals are one of the main advantages of the proposed method, these are easy to implement and have a simple calibration, which make their on-line application suitable. The effectiveness of this method was validated by simulation for the process of copolymerization in emulsion between butyl acrylate and styrene.
Service Browser in Linux Environment
Authors:   V. A. Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, 117997, Russian Federation, Kurako E. A. , Asratian R. E. ,   V. A. Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, 117997, Russian Federation, Orlov V. L. ,   V. A. Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, 117997, Russian Federation
Published: May 2024

The key features of using web browsers and service browsers as clients of information systems are considered. A minimal set of methods has been defined that is sufficient for the effective support of client functioning. A comparison is made of the main methods that a browser used as a universal means of providing client applications should include. The basic steps of the service-browser algorithm are presented. The service browser has the full range of necessary ways to process information from the client. At the same time, it is more lightweight than a web browser. However, well-known service browsers operate in a Windows environment, which limits the scope of use. The possibility of transferring and using a C#-based service browser from a Windows environment to a Linux environment is considered. The base problems with the transfer are described. Migration methods are proposed. Using the example of the service module "System Manager", which is actually identical in both systems, a comparative analysis of the work was carried out. In order to estimate only the operating time of the service-browser components, a unified database management system is used. The launch of the main modules in the Linux environment is somewhat faster, which is explained by the features of GTK widgets. At the same time, in the Windows environment, it is much easier to develop systems with a complex graphical interface due to a richer palette of visual components. Existing web browsers are quite cumbersome and contain many functions that may be unnecessary for the development of information systems. A compact solution that includes all the necessary methods for use in the client is to use a service-browser. This paper proposes a method for building service browsers in the Linux environment based on the C# language and the Mono package, taking into account the developed additional components.
ON THE QUESTION OF REMEDIES AVAILABLE TO THE EMPLOYEE IN CASE OF UNLAWFUL DISMISSAL
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Vavzhenchuk Serhii , Hryshyna Yuliia Hryshyna ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Mydel Andriy ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Published: May 2024

The article, on the basis of scientific doctrine, legislation of Ukraine, as well as judicial practice, examines certain issues related to the protection of an employee from wrongful dismissal in Ukraine, particularly, regarding the peculiarities of the application of such a remedy as reinstatement in the Ukrainian legal order. The authors emphasize the existence of a functional connection between the right to work, enshrined in the Constitution of Ukraine, and the employee's right to apply for protection in case of a wrongful dismissal by the employer. The article indicates the means of protection that can theoretically be applied by an employee who has been dismissed in violation of the requirements of the law. It is noted that reinstatement, based on the provisions of the legislation of Ukraine, can be considered the leading remedy available to the employee in case of a wrongful dismissal. At the same time, the authors note that the Labor Code of Ukraine does not provide the employee with an opportunity to choose a remedy that would reflect the needs of the particular employee in the most sufficient way. The article also attempts to explain the legal nature of reinstatement from the point of view of legal facts theory. In addition, the authors note that the proposed approach to the analysis of reinstatement allows explaining the compensation of average earnings for the period when the employee did not work because of the wrongful dismissal. This compensation can be interpreted as a natural consequence of reinstatement. At the same time, attention is focused on certain aspects of the relationship between the reinstatement of the employee and the payment to the employee of average earnings during the period of forced absenteeism. The article also describes the attitude of certain international organizations to reinstatement in the context of assessing the level of protection of employees under certain jurisdiction.
ORGANIZATIONAL AND LEGAL METHODS OF COMBATING MANIPULATION OF CITIZENS ’CONSCIOUSNESS IN SOCIAL NETWORKS
Authors:   National Academy of Security Service of Ukraine, Chernysh R.
Published: May 2024

The article states that in the XXI century the Internet and social networks are increasingly used to the detriment of national interests. Due to the total computerization and digitalization of humanity, cyberspace is becoming an environment for cybercrime. At the same time, the threat of excessive distribution of destructive content to manipulate the minds of citizens is urgent. In view of the above, the purpose of the article is to develop effective organizational and legal methods to combat this negative phenomenon. It is noted that the current legislation establishes an exclusive list of grounds for processing (and as its component – collection) of personal data. Among them, one of the key, in the context of the collection of personal data on the Internet, except in some cases, is the consent of the personal data subject. However, it was concluded that, currently, not all Internet resources or mobile applications warn about the processing of personal information. Preferably, you can find out by analyzing the appropriate settings or permissions (sometimes by default). Also, according to the privacy policy of social networks, mobile applications, access to the processing of personal data is a prerequisite for the use of services. That is, there is no alternative, and the consent itself by its legal nature is conditionally voluntary. It is alleged that the issue of processing information (personal data) about third parties is problematic. After all, in the case when a user provides access to his own page on a social network or a phone book – he automatically provides access to data about third parties without any of their personal consent. That is, in practice there is a situation in which the right to protection of this category of persons is systematically violated. The legal experience of the European Union countries in the field of ensuring the security of personal data of citizens is analyzed. The final part of the study emphasizes that the users of the Internet and social networks are representatives of public authorities, local governments, servicemen, employees of national law enforcement agencies and special services, and other secret agents. Accordingly, further scientific development requires strengthening of legal support and purposeful application of organizational measures, first of all, in the specified environment which can be used by foreign special services, in particular by the Russian Federation, in the interests.
On the Necessity to Transform the BRICS Trade Union Forum
Authors: Morozov P. E.
Published: May 2024

The article is devoted to topical issues of improving the activities of the BRICS Trade Union Forum, which is especially important from the point of view of expanding this international organization and the need to optimize supranational social partnership in terms of deepening the trend of international regionalization. The existing problems of the trade union movement at the BRICS level are generated by the presence of various models of employee representation in labor relations in the BRICS countries and the absence of an international legal act on the principles of organization and functioning of trade unions in the BRICS countries. The solution to the problems is seen in the need to transform the format of the BRICS Trade Union Forum, its name, as well as to develop common approaches to the trade union movement, which, of course, will contribute to optimizing the legal regulation of the protection of workers’ labor rights in the BRICS countries.
Legal Regulation of Women’s Labor in the BRICS Countries: Current Trends
Authors: Shesteryakova I. V.
Published: May 2024

The article discusses issues of legal regulation of women’s labor in the BRICS countries. The author draws attention to the latest labor legislation adopted in these countries recently. The need to consider this issue is dictated by the fact that almost half of the working population, including in the BRICS countries, are women. The study identified current trends in relation to the legal regulation of women’s labor. It has been established that all countries have adopted legislation restricting the work of women in jobs with harmful and (or) dangerous working conditions. States are taking measures to establish additional opportunities for women to advance in their careers and occupy leadership and government positions. Despite the efforts being made, there are also negative trends, such as discrimination in hiring and during employment, in remuneration, and the inability to occupy higher positions.
Genetic and Digital Discrimination in Labor Law: Problem Statement
Authors: Chernyh N. V.
Published: May 2024

The last few decades have been characterized by the most active development of medicine and genetics, leading to the emergence of new knowledge about the functioning of the human body. The identification of a genetic predisposition to the development of certain diseases requires a rethink of traditional approaches to the use of employee personal data, labor protection, and the balance of public and private interests in labor legislation. This article analyzes approaches to determining the legal nature of genetic information, identifies possible areas of restriction of workers’ rights depending on the identification of hereditary predisposition to certain diseases, draws a line between discrimination based on genetic characteristics and differentiation. In the context of the active digitalization of personnel processes, the risks of possible digital discrimination in the selection and evaluation of employees using artificial intelligence technologies are noted.
Protection of Honor and Dignity in Labor Relations
Authors: Rogaleva G. A. , Rogaleva I. Yu.
Published: May 2024

In the article we examined one of the current problems, the problem of protecting the honor and dignity of workers during their working life. A certain difficulty arises in applying this principle in practice; employers are increasingly restricting the rights and freedoms of employees. Gender discrimination is unacceptable, since a person’s biological characteristics should not be a determining factor when hiring. The solution to the problems of gender inequality in the Russian labor market should be carried out gradually, starting with recognition at the state level of the existence of this problem. We believe that this problem has existed for a long time and is inherent in every team, therefore it is imperative to develop effective means of protection not only at the legislative level, but also at the local level, which can consider the characteristics of all aspects of labor relations.
Some aspects of social security legislation in the light of constitutional changes
Authors: Kobzeva S. I.
Published: May 2024

This article is dedicated to the issue of improving legal regulation in the field of social security, taking into account constitutional amendments. The author explores the role and significance of the Russian Constitution as a system-forming source of law, analyzes the changes concerning the formation of the pension system based on the principles of universality, fairness, and generational solidarity. The article provides an assessment of the current state of pension legislation and considers the possibility of enhancing the effectiveness of the pension system in the implementation of constitutional changes.
Distinction of Competencies in the Legal Regulation of Social Security in the Context of Federalization
Authors: Akatnova M. I.
Published: May 2024

The article considers interaction forms in the field of legal regulation of social security between state authorities: federal and regional. In social security law, as in a number of other branches of Russian law, the combination of various levels of legal regulation is essential for the implementation of the constitutional right of people to social security, while leading to a number of problems in rule-making and law enforcement. The right to social security guaranteed by the Constitution of the Russian Federation to categories of persons in need of it, providing them with material support measures provided for by laws of social risks in a timely manner and to the fullest extent possible, in conditions of federalism, can be implemented with the participation of state authorities at all levels of legal regulation, from the federal to the level of local self-government. It was concluded that the state authorities of the constituent entities of the Russian Federation have a wide range of powers, the use of which allows them to more effectively implement the right of people to social security.
The Principle of Unity and Differentiation in Modern Labor Protection Legislation
Authors: Khristoforov N. R.
Published: May 2024

This article examines the manifestation of principle of unity and differentiation in the field of work safety. The institution of work safety is characterized by an imperative nature of legal regulation. Differentiation is mainly carried out based on the obligations imposed on employers by the legislature. The legislature has established an open list of regulatory acts containing normative requirements for work safety, which implies further development of new types of such acts, providing effectiveness and flexibility in legal regulation. However, there is uncertainty regarding the form, types, and functions of such regulatory acts. It is proposed to legislatively establish a classification of normative requirements for work safety by dividing them into norms aimed at “protecting health from harmful factors” and “protecting body from dangerous factors leading to injury.”
Generative Design of Progressive Die
Authors: Kumar Mahendhar , Akash V , Akash S , Sivarajan S
Published: May 2024

The evolution of products, dictated by the necessity to survive in the market, requires multi manufacturing processes to be performed simultaneously. Progressive die is one type of tool in which several individual stations are arranged in sequence. Each station will perform one or more various operations on the part. It is widely used to manufacture parts for automobile and other industries. This process with the help of progressive die is a very inexpensive method for forming moderate to large volume parts while keeping labor and die costs down. This study is dedicated to providing a 3D Computer-Aided Design (CAD) model for simple and economical progressive die construction which is suitable for the mass production of an industrial bracket. Different forces and stress convoluted in performing metal operations were also calculated with an appropriate formula. Generative designing technologies are also applied to yield the most efficient design economically as well as productively without compromising the optimum features of the tool. Various contours representation of data obtained is also presented in this work.
Design and Development of Portable Wrist Rehabilitation Device for Post-Stroke Subjects: A Pilot Study
Authors: Jayavel Porkodi , Karthik Varshini , Devaraj Ashokkumar
Published: May 2024

Wrist mobility is vital for post-stroke patients to carry out their daily activities. The use of robotic devices in hand rehabilitation has increased significantly in recent years, allowing patients to get training at home and effectively compensating for the therapist-to-patient ratio. Nevertheless, rehabilitation devices are expensive, cumbersome, immobile, and difficult to wear and operate. This work proposes a new method for designing a wrist rehabilitation device that uses airbag technology to minimize device weight and size. A triangular prism-shaped Neoprene (synthetic rubber) airbag is utilized in the experiment; which is inflated and deflated using a DC motorized air pump. An accelerometer sensor serves as the control input for the wrist rehabilitation exercise device. The proposed device trains the impaired hand of ten hemiplegic post-stroke patients. A goniometer and Fugl-Meyer Assessment (FMA) are used to measure wrist motion before and after the training regimen to evaluate the results. The mean angle (in degree) of wrist flexion increases from 8.6 ± 2.59 to 18.4 ± 5.19 (p = 0.005). Likewise, an increase in the wrist extension angle from 12.3 ± 3.62 to 17.7 ± 6.2 (p = 0.008) is noted. The wrist rehabilitation device is lightweight, portable, and simple to use, producing good results for hemiplegic individuals with hand disability. The suggested invention enables the user to extend their wrist’s range of motion.
Experimental animal models in traumatic brain injury research: a comprehensive review of methods and outlook
Authors: Saidu Umar Faruk , Bulama Ibrahim , Onu Andrew , Abbas Abdullahi Yahaya , Saidu Yusuf , Bilbis Lawal Suleman
Published: May 2024

Traumatic brain injury (TBI) remains a significant public health concern worldwide, necessitating effective research models to elucidate its pathophysiology and develop therapeutic interventions. Animal models play a crucial role in TBI research, offering valuable insights into injury mechanisms and potential treatments. However, selecting the appropriate model can be challenging due to diverse array of available options and their respective advantages and limitations. In this comprehensive review, we examine four commonly used animal models of TBI: the weight drop, fluid percussion, cortical impact, and blast injury models. Each model is characterized by distinct injury mechanisms, allowing researchers simulate various aspects of TBI pathology. We discuss the unique advantages and disadvantages of each model, providing insights into their applications and considerations for model selection based on research objectives and outcome measures. Furthermore, we highlight emerging directions in TBI modelling, emphasizing the importance of refining and innovating models to replicate the complexity of human TBI. By critically evaluating and understanding the subtlety of different TBI models, researchers can make informed decisions to enhance the translational potential of preclinical TBI research and ultimately improve clinical outcomes for TBI patients.
Temas de Historia del Arte. Escenarios, contextos y relatos
Authors:   Universidad de Castilla-La Mancha, Notario Sánchea Álvaro
Published: May 2024

Debatir, reflexionar y pensar la historia del arte desde las diversas metodologías se convierte en un ejercicio esencial para la redefinición de la disciplina. Además de la puesta en valor de las nuevas perspectivas, la historia del arte de nuestros días se preocupa por la divulgación y la interpretación del patrimonio, por el turismo, los medios de masas y la reflexión sobre los discursos museológicos. También se encarga del estudio de las nacientes formas de expresión artística, la inclusión de los nuevos públicos o los estudios de género y decoloniales. Este libro colectivo plantea una mirada a todos estos temas a través de las investigaciones de especialistas en distintos ámbitos de una historia del arte cada vez más transversal y multifocal, que no renuncia a su tradición historiográfica, pero tampoco a la vanguardia de los nuevos discursos.
Niosome-encapsulated auraptene reduced the mRNA expression of VEGF-A and PDGFs genes in human retina-derived RPE cell line
Authors:   Student Research Committee, Golestan University of Medical Sciences, Gorgan 4934174611, Iran, Vahidi Akram , Dastaviz Farzad ,   Student Research Committee, Golestan University of Medical Sciences, Gorgan 4934174611, Iran, Arabi Mehdi Sheikh ,   Department of Medical Nanotechnology, Faculty of Advanced Medical Technologies, Golestan University of Medical Sciences, Gorgan 4934174611, Iran, Khosravi Ayyoob ,   Stem Cell Research Center, Golestan University of Medical Sciences, Gorgan 4934174611, Iran; Department of Molecular Medicine, Faculty of Advanced Medical Technologies, Golestan University of Medical Sciences, Gorgan 4934174611, Iran, Oladnabi Morteza ,   Stem Cell Research Center, Golestan University of Medical Sciences, Gorgan 4934174611, Iran; Gorgan Congenital Malformations Research Center, Golestan University of Medical Sciences, Gorgan 4934174611, Iran
Published: May 2024

AIM: To evaluate the effect of auraptene (AUR) treatment in forms of free and encapsulated in niosome nanoparticles by investigating the mRNA expression level of vascular endothelium growth factor (VEGF)-A and platelet-derived growth factors (PDGFs) in human retinal pigment epithelium (RPE) cell line.
METHODS: Niosome nanocarriers were produced using two surfactants Span 60 and Tween 80. RPE cell line was treated with both free AUR and niosome-encapsulated. Optimum dosage of treatments was calculated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Expression of VEGF-A and PDGF-A, PDGF-B, PDGF-C, PDGF-D genes was measured after total RNA extraction and cDNA synthesis, using real-time polymerase chain reaction (RT-PCR).
RESULTS: The highest entrapment efficiency (EE) was achieved by Span 60:cholesterol (1:1) with 64.3%. The half maximal inhibitory concentration (IC50) of free and niosome-encapsulated AUR were 38.5 and 27.78 µg/mL, respectively. Release study revealed that niosomal AUR had more gradual delivery to the cells. RT-PCR results showed reduced expression levels of VEGF-A, PDGF-A, PDGF-B, PDGF-C, and PDGF-D after treatment with both free and niosomal AUR.
CONCLUSION: Niosomal formulation of Span 60: cholesterol (1:1) is an effective drug delivery approach to transfer AUR to RPE cells. VEGF-A, PDGF-A, PDGF-B, PDGF-C, and PDGF-D are four angiogenic factors, inhibiting which by niosomal AUR may be effective in age-related macular degeneration.