bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table S2 from Whole Exome and Transcriptome Analyses Integrated with Microenvironmental Immune Signatures of Lung Squamous Cell Carcinoma
Authors: Seo Jeong-Sun , Lee Ji Won , Kim Ahreum , Shin Jong-Yeon , Jung Yoo Jin , Lee Sae Bom , Kim Yoon Ho , Park Samina , Lee Hyun Joo , Park In-Kyu , Kang Chang-Hyun , Yun Ji-Young , Kim Jihye , Kim Young Tae
Published: April 2023

The differentially expressed genes of subtype A and B in LUSC.
Supplementary Table S3 from LncRNA-MM2P Identified as a Modulator of Macrophage M2 Polarization
Authors: Cao Ji , Dong Rong , Jiang Li , Gong Yanling , Yuan Meng , You Jieqiong , Meng Wen , Chen Zhanlei , Zhang Ning , Weng Qinjie , Zhu Hong , He Qiaojun , Ying Meidan , Yang Bo
Published: April 2023

table S3
Supplementary Materials and Methods from Selective Targeting of Glioblastoma with EGFRvIII/EGFR Bitargeted Chimeric Antigen Receptor T Cell
Authors: Jiang Hua , Gao Huiping , Kong Juan , Song Bo , Wang Peng , Shi Bizhi , Wang Huamao , Li Zonghai
Published: April 2023

Supplementary Materials and Methods
Supplementary Figures from Selective Targeting of Glioblastoma with EGFRvIII/EGFR Bitargeted Chimeric Antigen Receptor T Cell
Authors: Jiang Hua , Gao Huiping , Kong Juan , Song Bo , Wang Peng , Shi Bizhi , Wang Huamao , Li Zonghai
Published: April 2023

Figure S1-S6
Supplemental Figure Legend from Combining DNA Vaccine and AIDA-1 in Attenuated Salmonella Activates Tumor-Specific CD4+ and CD8+ T-cell Responses
Authors: Mei Yu , Zhao Lixiang , Liu Yonghao , Gong Huanle , Song Yuan , Lei Lei , Zhu Ying , Jin Ziqi , Ma Shoubao , Hu Bo , Sun Qing , Liu Haiyan
Published: April 2023

Supplemental Figure Legend
Supplementary Figure 4 from Anti–CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control
Authors: Sanseviero Emilio , O’Brien Erin M. , Karras Jenna R. , Shabaneh Tamer B. , Aksoy Bulent Arman , Xu Wei , Zheng Cathy , Yin Xiangfan , Xu Xiaowei , Karakousis Giorgos C. , Amaravadi Ravi K. , Nam Brian , Turk Mary Jo , Hammerbacher Jeff , Rubinstein Mark P. , Schuchter Lynn M. , Mitchell Tara C. , Liu Qin , Stone Erica L.
Published: April 2023

Supplementary Figure 4
Supplementary Tables from The Gut Microbiome Is Associated with Clinical Response to Anti–PD-1/PD-L1 Immunotherapy in Gastrointestinal Cancer
Authors: Peng Zhi , Cheng Siyuan , Kou Yan , Wang Ziqi , Jin Rong , Hu Han , Zhang Xiaotian , Gong Ji-fang , Li Jian , Lu Ming , Wang Xicheng , Zhou Jun , Lu ZhiHao , Zhang Quan , Tzeng David T.W. , Bi Dongtao , Tan Yan , Shen Lin
Published: April 2023

Supplementary Tables
Supplementary Figures 1-6 from Dysregulated NF-κB–Dependent ICOSL Expression in Human Dendritic Cell Vaccines Impairs T-cell Responses in Patients with Melanoma
Authors: Maurer Deena M. , Adamik Juraj , Santos Patricia M. , Shi Jian , Shurin Michael R. , Kirkwood John M. , Storkus Walter J. , Butterfield Lisa H.
Published: April 2023

Supplementary Figures 1-6
Figure S4 from Pathogen-Boosted Adoptive Cell Transfer Therapy Induces Endogenous Antitumor Immunity through Antigen Spreading
Authors: Xin Gang , Khatun Achia , Topchyan Paytsar , Zander Ryan , Volberding Peter J. , Chen Yao , Shen Jian , Fu Chunmei , Jiang Aimin , See William A. , Cui Weiguo
Published: April 2023

Generation of CD11c-DTR/WT and CD11c-DTR/Batf3-/- bone marrow chimeras
Supplementary Data from Immune-Checkpoint Protein VISTA Regulates Antitumor Immunity by Controlling Myeloid Cell–Mediated Inflammation and Immunosuppression
Authors: Xu Wenwen , Dong Juan , Zheng Yongwei , Zhou Juan , Yuan Ying , Ta Hieu Minh , Miller Halli E. , Olson Michael , Rajasekaran Kamalakannan , Ernstoff Marc S. , Wang Demin , Malarkannan Subramaniam , Wang Li
Published: April 2023

Figure S1 S2 and S3
Supplementary Methods and Legends from CD96 Is an Immune Checkpoint That Regulates CD8+ T-cell Antitumor Function
Authors: Mittal Deepak , Lepletier Ailin , Madore Jason , Aguilera Amelia Roman , Stannard Kimberley , Blake Stephen J. , Whitehall Vicki L.J. , Liu Cheng , Bettington Mark L. , Takeda Kazuyoshi , Long Georgina V. , Scolyer Richard A. , Lan Ruth , Siemers Nathan , Korman Alan , Teng Michele W.L. , Johnston Robert J. , Dougall William C. , Smyth Mark J.
Published: April 2023

Supp Methods and Legends S1-S10
Supplementary Figures from Head and Neck Cancers Promote an Inflammatory Transcriptome through Coactivation of Classic and Alternative NF-κB Pathways
Authors: Yang Xinping , Cheng Hui , Chen Jianhong , Wang Ru , Saleh Anthony , Si Han , Lee Steven , Guven-Maiorov Emine , Keskin Ozlem , Gursoy Attila , Nussinov Ruth , Fang Jugao , Van Waes Carter , Chen Zhong
Published: April 2023

Supplementary Figures.
Supplementary Data from RIPK3 Orchestrates Fatty Acid Metabolism in Tumor-Associated Macrophages and Hepatocarcinogenesis
Authors: Wu Lei , Zhang Xiao , Zheng Lu , Zhao Huakan , Yan Guifang , Zhang Qi , Zhou Yu , Lei Juan , Zhang Jiangang , Wang Jingchun , Xin Rong , Jiang Lu , Peng Jin , Chen Qian , Lam Sin Man , Shui Guanghou , Miao Hongming , Li Yongsheng
Published: April 2023

Table S1, Figure S1-S7
Figure S4 from Tumor-Derived IL33 Promotes Tissue-Resident CD8+ T Cells and Is Required for Checkpoint Blockade Tumor Immunotherapy
Authors: Chen Lujun , Sun Runzi , Xu Junchi , Zhai Wensi , Zhang Dachuan , Yang Min , Yue Cuihua , Chen Yichao , Li Song , Turnquist Heth , Jiang Jingting , Lu Binfeng
Published: April 2023

IL-33 was expressed in tumor cells but not in CD45+CD11b+, CD45+CD3+, CD45-CD31+, or CD45-FSP1+ cells
Supplementary Figures and Tables from KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1
Authors: Bhatt Rupal S. , Berjis Abdulla , Konge Julie C. , Mahoney Kathleen M. , Klee Alyssa N. , Freeman Samuel S. , Chen Chun-Hau , Jegede Opeyemi A. , Catalano Paul J. , Pignon Jean-Christophe , Sticco-Ivins Maura , Zhu Baogong , Hua Ping , Soden Jo , Zhu Jie , McDermott David F. , Arulanandam Antonio R. , Signoretti Sabina , Freeman Gordon J.
Published: April 2023

Supplementary Figures 1-7 and Supplementary Tables 1-2
Figure S3 from Tumor-Derived IL33 Promotes Tissue-Resident CD8+ T Cells and Is Required for Checkpoint Blockade Tumor Immunotherapy
Authors: Chen Lujun , Sun Runzi , Xu Junchi , Zhai Wensi , Zhang Dachuan , Yang Min , Yue Cuihua , Chen Yichao , Li Song , Turnquist Heth , Jiang Jingting , Lu Binfeng
Published: April 2023

Characteristics of TIL in ST2+/+ and ST2-/- mice after ICB therapy
Supplementary Data File 1 from Rationally Designed Transgene-Encoded Cell-Surface Polypeptide Tag for Multiplexed Programming of CAR T-cell Synthetic Outputs
Authors: Johnson Adam J. , Wei Jia , Rosser James M. , Künkele Annette , Chang Cindy A. , Reid Aquene N. , Jensen Michael C.
Published: April 2023

Supplementary Data File 1
Table S1 from Demographic Factors Associated with Toxicity in Patients Treated with Anti–Programmed Cell Death-1 Therapy
Authors: Shah Kaustav P. , Song Haocan , Ye Fei , Moslehi Javid J. , Balko Justin M. , Salem Joe-Elie , Johnson Douglas B.
Published: April 2023

Number and percentage of reported cases of colitis, autoimmune hepatitis, pneumonitis, and myocarditis based on age group reported in Vigibase.
Supplementary Table 3 from Overcoming Acquired Epigenetic Resistance to BTK Inhibitors
Authors: Shaffer Arthur L. , Phelan James D. , Wang James Q. , Huang DaWei , Wright George W. , Kasbekar Monica , Choi Jaewoo , Young Ryan M. , Webster Daniel E. , Yang Yandan , Zhao Hong , Yu Xin , Xu Weihong , Roulland Sandrine , Ceribelli Michele , Zhang Xiaohu , Wilson Kelli M. , Chen Lu , McKnight Crystal , Klumpp-Thomas Carleen , Thomas Craig J. , Häupl Björn , Oellerich Thomas , Rae Zachary , Kelly Michael C. , Ahn Inhye E. , Sun Clare , Gaglione Erika M. , Wilson Wyndham H. , Wiestner Adrian , Staudt Louis M.
Published: April 2023

Supplemental Table 3. Epigenetic retuning of oncogenic signaling in ibrutinib resistance, relates to Fig. 3
Supplementary Table 1 from Overcoming Acquired Epigenetic Resistance to BTK Inhibitors
Authors: Shaffer Arthur L. , Phelan James D. , Wang James Q. , Huang DaWei , Wright George W. , Kasbekar Monica , Choi Jaewoo , Young Ryan M. , Webster Daniel E. , Yang Yandan , Zhao Hong , Yu Xin , Xu Weihong , Roulland Sandrine , Ceribelli Michele , Zhang Xiaohu , Wilson Kelli M. , Chen Lu , McKnight Crystal , Klumpp-Thomas Carleen , Thomas Craig J. , Häupl Björn , Oellerich Thomas , Rae Zachary , Kelly Michael C. , Ahn Inhye E. , Sun Clare , Gaglione Erika M. , Wilson Wyndham H. , Wiestner Adrian , Staudt Louis M.
Published: April 2023

Supplemental Table 1. Epigenetic Ibrutinib Resistance in ABC DLBCL lines, , relates to Fig. 1
Supplementary Figures and Legends from Overcoming Acquired Epigenetic Resistance to BTK Inhibitors
Authors: Shaffer Arthur L. , Phelan James D. , Wang James Q. , Huang DaWei , Wright George W. , Kasbekar Monica , Choi Jaewoo , Young Ryan M. , Webster Daniel E. , Yang Yandan , Zhao Hong , Yu Xin , Xu Weihong , Roulland Sandrine , Ceribelli Michele , Zhang Xiaohu , Wilson Kelli M. , Chen Lu , McKnight Crystal , Klumpp-Thomas Carleen , Thomas Craig J. , Häupl Björn , Oellerich Thomas , Rae Zachary , Kelly Michael C. , Ahn Inhye E. , Sun Clare , Gaglione Erika M. , Wilson Wyndham H. , Wiestner Adrian , Staudt Louis M.
Published: April 2023

Supplemental Information- Figures & Legends (Supplemental Tables loaded separately)
Supplementary Figure 7 from Tumor Purity in Preclinical Mouse Tumor Models
Authors: Qian Wubin , Chen Xiaobo , Sheng Yanghui , Zhang Likun , Wang Jingjing , Song Zhenzhen , Li Qi-Xiang , Guo Sheng
Published: April 2023

The distribution of tumor purity in mouse cells for 2115 PDX models within passage 10.
Supplementary Figure 4 from Tumor Purity in Preclinical Mouse Tumor Models
Authors: Qian Wubin , Chen Xiaobo , Sheng Yanghui , Zhang Likun , Wang Jingjing , Song Zhenzhen , Li Qi-Xiang , Guo Sheng
Published: April 2023

The distribution of tumor purity in human cells of 2115 PDX models within passage 10.
Supplementary Figure 3 from Tumor Purity in Preclinical Mouse Tumor Models
Authors: Qian Wubin , Chen Xiaobo , Sheng Yanghui , Zhang Likun , Wang Jingjing , Song Zhenzhen , Li Qi-Xiang , Guo Sheng
Published: April 2023

Median variant allelic fraction (VAF) of missense mutations in cancer cell lines and patient tumors.
Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition)
Authors: Zhou Jian , Sun Huichuan , Wang Zheng , Cong Wenming , Zeng Mengsu , Zhou Weiping , Bie Ping , Liu Lianxin , Wen Tianfu , Kuang Ming , Han Guohong , Yan ZhiPing , Wang Maoqiang , Liu Ruibao , Lu Ligong , Ren Zhenggang , Zeng ZhaoChong , Liang Ping , Liang Changhong , Chen Min , Yan Fuhua , Wang Wenping , Hou Jinlin , Ji Yuan , Yun Jingping , Bai Xueli , Cai Dingfang , Chen Weixia , Chen Yongjun , Cheng Wenwu , Cheng Shuqun , Dai Chaoliu , Guo Wenzhi , Guo Yabing , Hua Baojin , Huang Xiaowu , Jia Weidong , Li Qiu , Li Tao , Li Xun , Li Yaming , Li Yexiong , Liang Jun , Ling Changquan , Liu Tianshu , Liu Xiufeng , Lu Shichun , Lv Guoyue , Mao Yilei , Meng Zhiqiang , Peng Tao , Ren Weixin , Shi Hongcheng , Shi Guoming , Shi Ming , Song Tianqiang , Tao Kaishan , Wang Jianhua , Wang Kui , Wang Lu , Wang Wentao , Wang Xiaoying , Wang Zhiming , Xiang Bangde , Xing Baocai , Xu Jianming , Yang Jiamei , Yang Jianyong , Yang Yefa , Yang Yunke , Ye Shenglong , Yin Zhenyu , Zeng Yong , Zhang Bixiang , Zhang Boheng , Zhang Leida , Zhang Shuijun , Zhang Ti , Zhang Yanqiao , Zhao Ming , Zhao Yongfu , Zheng Honggang , Zhou Ledu , Zhu Jiye , Zhu Kangshun , Liu Rong , Shi Yinghong , Xiao Yongsheng , Zhang Lan , Yang Chun , Wu Zhifeng , Dai Zhi , Chen Minshan , Cai Jianqiang , Wang Weilin , Cai Xiujun , Li Qiang , Shen Feng , Qin Shukui , Teng Gaojun , Dong Jiahong , Fan Jia
Published: April 2023

Background: Primary liver cancer, of which around 75–85% is hepatocellular carcinoma in China, is the fourth most common malignancy and the second leading cause of tumor-related death, thereby posing a significant threat to the life and health of the Chinese people. Summary: Since the publication of Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China in June 2017, which were updated by the National Health Commission in December 2019, additional high-quality evidence has emerged from researchers worldwide regarding the diagnosis, staging, and treatment of liver cancer, that requires the guidelines to be updated again. The new edition (2022 Edition) was written by more than 100 experts in the field of liver cancer in China, which not only reflects the real-world situation in China but also may reshape the nationwide diagnosis and treatment of liver cancer. Key Messages: The new guideline aims to encourage the implementation of evidence-based practice and improve the national average 5-year survival rate for patients with liver cancer, as proposed in the “Health China 2030 Blueprint.”
Penerapan Model Flipped classroom dalam Pembelajaran Daring pada Mata Kuliah Metode Pembelajaran, Studi Kurikulum, dan Telaah Kurikulum di Universitas Pelita Harapan
Authors: Martha Kurniawati , Zega Eben Hezer
Published: April 2023

Pembelajaran daring di masa pandemi menjadi tantangan bagi Dosen dalam mengelola pembelajaran yang menarik dan dapat membekali mahasiswa menjadi insan yang terampil, serta mampu menghadapi tantangan di masa depan. Praktik yang ditemui di kelas menunjukkan pembelajaran daring yang kurang aktif, kurang interaktif, dan kurang menyenangkan, serta siswa yang kurang antusias, inisiatif, dan tanggap. Solusi yang diberikan peneliti adalah penerapan model flipped classroom dalam mengelola pembelajaran online. Penelitian ini bertujuan untuk menjelaskan pentingnya peran Dosen dalam mengelola pembelajaran daring dan menjelaskan upaya Dosen dalam mengefektifkan pembelajaran daring dengan menggunakan model flipped classroom. Metodologi penelitian yang digunakan adalah deskriptif kualitatif dengan memanfaatkan hasil observasi, hasil penilaian dan angket yang diisi oleh mahasiswa didukung dengan studi literatur. Penerapan model flipped classroom dilakukan pada mata kuliah Kajian Kurikulum, Metode Pembelajaran, dan Review Kurikulum pada bulan Januari–April 2021. Hasil penelitian menunjukkan bahwa model flipped classroom mampu membantu Dosen mengelola pembelajaran online. Dalam penerapan yang lebih efektif, Dosen disarankan untuk lebih mengenal mahasiswa secara holistik dan terus mengembangkan diri, sehingga dapat mendukung manajemen pembelajaran yang baik.
Voice Recognition as a Mobile Robot Controller with the Adaptive Neuro-Fuzzy Inference System Method
Authors: Suhendra Muhamad Agung , Parlaungan Timbo Faritcan , Sumardi Tedi
Published: April 2023

Voice recognition or speech recognition is a biometric technology that has very wide applications, one of which is for simple robot motion control. There are three stages in this research, namely data acquisition, feature extraction, and data classification. For feature extraction, the wavelet transform method is used which can analyze non-stationary and non-linear signals, while for data classification, the Adaptive Neuro-Fuzzy Inference System (Anfis) method is used. The result of data classification is 92.25% and 7.75% error. So, based on the results of the classification accuracy, the robot can be moved via voice commands and to anticipate the error value, the ultrasonic sensor feature is added to the robot as an alternative control.
Thomas Ebendorfer on virtus sermonis and the Relation between Theology, Philosophy, and Logic
Authors: Curuț Ioana
Published: April 2023

The focus of this article is the manner in which Thomas Ebendorfer of Hasselbach, a Viennese theologian lecturing on Book I of the Sentences in 1421, deals with the topic of virtus sermonis and the relation between theology, philosophy, and logic in his Prologue from the autograph MS Wien, Österreichische Nationalbibliothek, 4369 (ff. 7r–8v). By combining a double classification of each science (into acquisita vs. infusa) with a double perspective of their relation (temporal vs. natural), and by making a strong claim for theology’s role in advancing new logical theories, Ebendorfer’s view reflects a progressive awareness of the distinction between theology and philosophy which, in turn, entails very different applications of virtus sermonis in the two sciences. An edition of the Prologue is provided in the Appendix.
The Annus magnus in Albert the Great’s Parisian Theological Works
Authors: Palazzo Alessandro
Published: April 2023

According to the doctrine of the Great Year, after a long period of time the same astral configurations reappear and the planets return to their original positions. The end of a world cycle is marked by a natural cataclysm, after which the world is restored to its original state and history repeats itself. This article deals with Albert the Great’s views on the Great Year, focussing on two of his early theological works (the De iv coaequaevis and the Sentences commentary). The evidence here provided offers a comprehensive overview of the variety of contexts and themes which Albert considers to be related to the Great Year. He is fully aware of the many doctrinal implications of the concept of the Great Year. His analysis is deeply embedded in the astronomical discussions on the phenomenon of the precession of the equinoxes. A predominantly scientific approach is evident in the care with which he distinguishes the different types of Great Year. The major contribution of these works to the debate lies in the analysis of the impact of the Great Year on Christian eschatology and, more generally, in the investigation of the relationship between astrology and physics, on the one hand, and eschatology, on the other.
The Quest for the Historical Jesus, 2000–2023
Authors: Massey Brandon
Published: April 2023

This article provides a bibliography of historical Jesus research from 2000 to 2023 in German and English language publications. In addition to the bibliography, a brief introductory essay identifies trends in historical Jesus research.
In Judgment of Unit 731: A Comparative Study of Medical War Crimes Trials after World War ii
Authors: Cranmer Valerie J.
Published: April 2023

The prosecution of the crimes of the Imperial Japanese Army’s Unit 731 are often compared to the prosecution of the crimes of the Nazi doctors. These comparisons emphasize immunity for the Japanese, whereas the Nazis were prosecuted for their actions. However, this comparison is an inaccurate one. While both trials look similar on the surface, their composition, scope, and framework were different. Conscious of the fact they were establishing international criminal precedent, the United States’ case against the Nazi doctors relied on military chain of command to prove strong legal responsibility for human experimentation crimes. In contrast, the United States avoided prosecuting Unit 731 because they could not replicate the same clear legal framework used to successfully prosecute the Nazis. The Soviet Union recognized the strategic implications of the United States’ decision not to try Unit 731 and saw an opportunity to strike a moral blow, not only by convicting Japanese military members at the Khabarovsk Trial, but also by immediately publishing the court’s proceedings internationally. Rather than focusing on the morality of who was punished by whom, understanding the military structures as identified through these different court proceedings could enable prevention of crimes against humanity.
Foreign Minister Tōgō’s Bitter Struggle and the Acceptance of the Potsdam Declaration
Authors: Kazuhiko Tōgō , Walsh Brian P.
Published: April 2023

Japan’s decision to accept the terms of the Potsdam Declaration was one of the most pivotal events in the country’s modern history. Most students of the decision-making process agree that Foreign Minister Tōgō Shigenori was the principal motive force supporting acceptance of the Allies’ demands throughout the debate over the action. Some recent historiography in Japan has questioned Tōgō’s approach, focusing particularly on his decision to seek the mediation of the Soviet Union and on the question of why he did not bring hostilities to an end sooner. Historical materials that were previously unavailable to scholars shed some light on these questions. In combination with Tōgō’s daily planner (in the author’s possession), his memoirs, and the author’s own recollection of anecdotes his parents told to him, these materials make possible a detailed examination of Tōgō’s thoughts and actions in the days leading to the acceptance of the Potsdam Declaration. This shows that Tōgō, facing stubborn resistance from the military and from public opinion, nevertheless persevered in his quest to bring the war to an end. He also maintained the trust and respect of not only Emperor Hirohito, but also of Army Minister Anami Korechika, his principal antagonist in the debate.
‘And the Nothing That Is’
Authors: Putt B. Keith
Published: April 2023

Richard Kearney has always insisted that his anatheistic approach to a phenomenology of the sacred stipulates a close connection with aesthetics. He supports this contention throughout his work by constantly referencing important artists, poets, novelists, and film makers. Indeed, this connection between aesthetics and his philosophy of religion has even motivated an anthology of articles entitled The Art of Anatheism. Consequently, in this essay I wish to expand that connection by examining the relationship between Kearney’s anatheism and the ‘supreme fiction’ of the American poet Wallace Stevens. To accomplish this expansion, I inspect several topics shared by the two authors, including God, faith, imagination, and ‘negative certainty’. This last topic forms something of the central focus of the essay, since I argue that the affirmative humility of faith professed by both never avoids the ‘void’ inherent in human existence that disallows every claim to the ‘innocence of an absolute’.
After Thoughts on After Gods
Authors: Kearney Richard
Published: April 2023

Richard Kearney offers a response to the Scriptorium on his work and its relation to the poetic imagination.
Two new species of Eperua (Leguminosae, Detarioideae, Detarieae) from the Amazon and Cerrado Biomes discovered in a botanical garden and a backyard
Authors: FORTES ELENICE A. , DA SILVA GUILHERME S. , MANSANO VIDAL F.
Published: April 2023

In this study, we describe two new species of Eperua, E. cerradoensis and E. manausensis. Eperua cerradoensis is the first species of the genus described from the Cerrado Biome (Brazil); all other 16 species, including the other new species described here E. manausensis, are endemic to the Amazon region (Amazon basin and the Guiana Shield). Both species have short and erect inflorescences. Eperua cerradoensis has a non-tubular corolla, white petals, and exserted stamens, and is most similar to E. duckeana and E. schomburgkiana, from which it differs by the bracteole size and phenology, flower indumentum, besides other vegetative characteristics. Eperua manausensis has a tubular corolla, pink to purple petals, and inserted stamens, and it is most similar to E. grandiflora subsp. guyanensis, but differs from it by the bracteole position and phenology and flower indumentum. The type localities of both species are very unusual: a backyard (E. cerradoensis) and a botanical garden (E. manausensis). The two species have been collected in the last five years. These discoveries show that new undescribed species can be found even in more disturbed areas and that comprehensive knowledge of the flora requires new collections and more taxonomists.
Pattern Projection Calibrations on Subseasonal Forecasts of Surface Air Temperature over East Asia
Authors: Zhu Shoupeng , Zhang Ling , Jiang Hangdong , Lyu Yang , Fan Yi , Guo Zhun , Zhi Xiefei
Published: April 2023

Subseasonal forecasts have recently attracted widespread interest yet remain a challenging issue. A statistical Kalman filter pattern projection method (KFPPM), which absorbs the projection conception of the raw covariance pattern projection (COVPPM) and the adaptive adjustments of the Kalman filter, is proposed to calibrate the single-model forecasts of the daily maximum and minimum temperatures (Tmax and Tmin) for lead times of 8–42 days over East Asia in 2018 derived from the UKMO control (CTL) forecast. The Kalman filter–based gridly calibration (KFGC) is carried out in parallel as a benchmark, which could improve the forecast skills to a certain extent. The COVPPM effectively calibrates the temperature forecasts at the early stage and displays better performances than the CTL and KFGC. However, with the growing lead times, it shows speedily decreasing skills and can no longer produce positive adjustments over the areas outside the plateaus. By contrast, the KFPPM consistently outperforms the other calibrations and reduces the forecast errors by almost 1.0° and 0.5°C for Tmax and Tmin, respectively, both retaining superiorities to the random climatology benchmark till the lead time of 24 days. The optimization of KFPPM maintains throughout the whole range of the subseasonal time scale, showing the most conspicuous improvements distributed over the Tibetan Plateau and its surroundings. Though the postprocessing procedures are more skillful in calibrating Tmax forecasts than Tmin forecasts, the Tmax forecasts are still characterized by lower skills than the latter. Case experiments further demonstrate the abovementioned features and imply the potential capability of KFPPM in improving forecast skills and disaster preventions for extreme temperature events.
A Longitudinal Cohort Study of Adolescent Social Network Positions and Lifetime Daily Smoking and Nicotine Dependence
Authors: Sohn Minsung , Moon Daseul , Kim Jinho
Published: April 2023

This study investigated the extent to which adolescent social network positions are associated with the risk of lifetime daily smoking and nicotine dependence (ND), and whether these associations differ by gender. Using data from the National Longitudinal Study of Adolescent to Adult Health ( N = 6,267), this study estimated multinomial logistic regression models. An increase in in-degree nominations, out-degree nominations, and Bonacich centrality was associated with a lower relative risk of never smoking daily versus ever smoking daily. By contrast, adolescents with greater in-degree nominations, out-degree nominations, Bonacich centrality, and network reach in three steps were at decreased risk for lifetime ND. Gender-stratified models indicate that the negative association between network position and never smoking daily was driven largely by women, whereas the positive association between network position and lifetime ND was driven largely by men. Incorporating social network structural approaches into adolescent smoking prevention efforts may be beneficial.
Reinforcing Political Inequality Through Diversity Initiatives: A Field-Level Perspective
Authors: Jakob Sadeh Linda , Mair Johanna
Published: April 2023

Although diversity initiatives are considered prominent vessels for addressing inequality and despite massive investments in them, inequality inside organizations persists. Assessments of diversity initiatives often center on economic inequality and view organizations as closed systems to explain why they fail. Building on a 19-month field-level ethnography of the diversity field in Israel targeting Palestinian employment, we examine political inequality and show how it is perpetuated even as economic inequality is dealt with. Our findings reveal that the field is complicit in creating a chasm between the economic and political spheres by positioning diversity initiatives as a means to tackle economic inequality. The field’s infrastructure and dominant discourse reinforce this chasm and thereby make political inequality invisible, generating false consciousness. Our study challenges the preoccupation of diversity scholarship with universal best practices, suggests avenues for assessing and managing diversity initiatives while taking stock of political inequality, and directs future research to delve into the relationship between the economic and the political in organizations and our societies.
Preceding transient ischemic attack was associated with functional outcome after stroke thrombectomy: A propensity score matching study
Authors: Xu Jiali , Guo Wenting , Ma Jin , Ma Qingfeng , Chen Jian , Song Haiqing , Ren Changhong , Li Sijie , Ding Yuchuan , Zhao Wenbo , Ji Xunming
Published: April 2023

Whether preceding transient ischemic attack (TIA) can provide neuroprotective benefits in subsequent acute ischemic stroke (AIS) caused by large vessel occlusion remains unclarified. This study aimed to investigate the association between preceding TIA and functional outcomes in AIS patients with endovascular therapy (EVT). Eligible patients were divided into TIA and non-TIA groups according to whether they experienced TIA within 96 hours prior to stroke. Two groups were balanced using propensity score matching (PSM) analysis at a 1:3 ratio. Onset stroke severity and 3-month functional independence were evaluated. A total of 887 patients were included. After PSM, 73 patients with and 217 patients without preceding TIA were well matched. Onset stroke severity was not different between the groups (p > 0.05). However, the TIA group had a lower systemic immune-inflammation index (SII) (median, 1091 versus 1358, p < 0.05). Preceding TIA was significantly associated with 3-month functional independence (adjusted odds ratio, 2.852; 95% confidence interval [CI], 1.481–5.495; adjusted p < 0.01). The effects of preceding TIA on functional independence were partially mediated by SII (average causal mediation effects 0.02; 95% CI, 0.001–0.06, p < 0.05). In AIS patients treated by EVT, preceding TIA within 96 hours was associated with three-month functional independence but not with reduced onset stroke severity.
Zoning Change: Upzonings, Downzonings, and Their Impacts on Residential Construction, Housing Costs, and Neighborhood Demographics
Authors: Freemark Yonah
Published: April 2023

Many policymakers concerned about high housing costs argue that easing development through altered land-use regulations can increase building, thereby boosting affordability and reducing segregation. I develop a framework to explain links—sometimes contradictory—between upzonings and construction, prices, and demographics. I evaluate scholarship and compare findings with research on downzoning's impeding development. Evidence indicates that upzonings offer mixed success in terms of housing production, reduced costs, and social integration in impacted neighborhoods; outcomes depend on market demand, local context, housing types, and timing. Research on regional upzoning impacts is nascent but outcomes appear positive. Downzonings limit construction and worsen affordability.
Development of a hierarchical control strategy for a soft knee exoskeleton based on wearable multi-sensor system
Authors: Wu Qingcong , Liu Huanrui , Chen Ying
Published: April 2023

Soft exoskeleton is a newly emerging approach for providing assistive forces to the movement of disabled individuals, which has aroused the interest of many researchers due to its promising prospects in rehabilitation training and motion assistance. In this article, a wearable wireless multi-sensor system and a hierarchical control architecture are developed for a soft knee exoskeleton. First, the major components of the soft knee exoskeleton are introduced, including the flexible Bowden-cable actuators, the soft wearable components, and the sensing modules and the control system. The wearable wireless multi-sensor system consists of an inertial measurement unit–based knee flexion–extension angle sensing module, a surface electromyogram–based joint torque estimation module, a miniature pulling force sensing module, and a central communication unit. And then, a three-level hierarchical control strategy—which fuses a high-level motion recognition and torque estimation algorithm, a mid-level knee trajectory generation strategy, and a low-level fuzzy impedance controller—is proposed to realize human motion assistance. Finally, experiments are carried out to verify the effectiveness of the proposed control strategy. The experimental setup is established with the soft knee exoskeleton, a treadmill, a wearable robotic rotary joint with an encoder, and an inelastic rope. The experimental result indicates that the root mean square errors of the joint angle estimation strategy and joint torque estimation strategy are less than 4.3° and 4.8 Nm, while the surface electromyogram–based assistance efficiency and torque-based assistance efficiency under different loading conditions are higher than 10.2% and 18.2%, respectively.
A Survey of Graph Comparison Methods with Applications to Nondeterminism in High-Performance Computing
Authors: Bhowmick Sanjukta , Bell Patrick , Taufer Michela
Published: April 2023

The convergence of extremely high levels of hardware concurrency and the effective overlap of computation and communication in asynchronous executions has resulted in increasing nondeterminism in High-Performance Computing (HPC) applications. Nondeterminism can manifest at multiple levels: from low-level communication primitives to libraries to application-level functions. No matter its source, nondeterminism can drastically increase the cost of result reproducibility, debugging workflows, testing parallel programs, or ensuring fault-tolerance. Nondeterministic executions of HPC applications can be modeled as event graphs, and the applications’ nondeterministic behavior can be understood and, in some cases, mitigated using graph comparison algorithms. However, a connection between graph comparison algorithms and approaches to understanding nondeterminism in HPC still needs to be established. This survey article moves the first steps toward establishing a connection between graph comparison algorithms and nondeterminism in HPC with its three contributions: it provides a survey of different graph comparison algorithms and a timeline for each category’s significant works; it discusses how existing graph comparison methods do not fully support properties needed to understand nondeterministic patterns in HPC applications; and it presents the open challenges that should be addressed to leverage the power of graph comparisons for the study of nondeterminism in HPC applications.
A metatheoretical framework for organizational wellbeing research: Toward conceptual pluralism in the wellbeing debate
Authors: Kenttä Peter , Virtaharju Jouni
Published: April 2023

The organizational wellbeing discourse has in the past decades gravitated toward two adversarial camps. The first camp draws increasingly from positive psychology and studies wellbeing as the presence of positive attributes centered around the individual. The second camp is critical toward the first one from a sociological standpoint by warning about its hidden tyranny and detrimental organizational consequences. In this paper we interrogate the conceptual foundations of the two camps and argue that the paradigmatic divide between them can be traced to their antithetical assumptions about the nature of human freedom. To move beyond the paradigmatic standstill, we suggest adopting Kenneth Burke’s dramatistic pentad as a metatheoretical framework for organizational wellbeing research. The pentad can help integrate concerns and viewpoints from both camps and facilitate the exploration of novel opportunities to conceptualize wellbeing in organizations. The proposed metatheoretical framework acknowledges the plural and essentially contested character of wellbeing whilst promoting theoretical pluralism in organizational wellbeing research. We also illustrate the use of the dramatistic pentad through three thought-provoking conceptualizations of organizational wellbeing. The illustrations show how the dramatistic pentad can be used to spur much needed conceptual imagination within organizational wellbeing research.
Genetic evidence of the function of Phox2a-expressing anterolateral system neurons in the transmission of chronic pain
Authors: Zhang Xinying , Millecamps Magali , Kania Artur
Published: April 2023

The development of the chronic neuropathic pain state often originates at the level of peripheral sensory neurons, whose abnormal function elicits central sensitization and maladaptive plasticity in the nociceptive circuits of the spinal dorsal horn. These changes eventually reach supraspinal areas bringing about cognitive and affective co-morbidities of chronic pain such as anxiety and depression. This transmission presumably relies on the function of spinal projection neurons at the origin of the anterolateral system (AS). However, the identity of these neurons and the extent of their functional contribution remain unknown. Here, we asked these questions in the context of the mouse AS neurons that require the transcription factor Phox2a for their normal target connectivity and function in transmitting acute nociceptive information to the brain. To this end, we examined the effects of a spinal cord-specific loss of Phox2a (Phox2acKO) on the development of central sensitization evoked by the spared nerve injury (SNI) model of chronic pain. We found that SNI-treated Phox2acKO mice developed normal reflexive spinal responses such as mechanical allodynia evidenced by a decreased withdrawal threshold to von Frey filament stimulation and dynamic brush. On the other hand, Phox2acKO attenuated the development of cold but not mechanical hyperalgesia, in behavioral paradigms that require the relay of nociceptive information to the brain. Furthermore, Phox2acKO attenuated anxio-depressive-like behaviors evoked by SNI, measured by performance in the open field test and tail suspension test. Thus, Phox2a AS neurons play a critical role in the generation and maintenance of chronic neuropathic pain.
The past and the present: Following in the footsteps of a neo-Nazi movement in a rural Sweden school
Authors: Mattsson Christer , Johansson Thomas
Published: April 2023

This case study aimed to describe and analyse how students and staff at a school in a geographical area with a tradition of high neo-Nazi activism perceived and talked about racism and sexism in particular, and the ‘school climate’ in general. The case consists of 10 school professionals and 14 students. The selected school was located in a traditional mill town, once built around a dominating industry, but over the last decades it has been characterised by deindustrialisation and economic decline. The town became the founding area of the Swedish National Socialist movement during the interwar period and has since hosted vital parts of the movement, which is ongoing. Today, the local movement comprises middle-aged former skinheads who have children attending the local school. The study scrutinised the encounter between the mill town’s ingrained racism and the school’s duty to prevent racism and promote tolerance. The outcome shows how Nazi movement has generationally reproduced itself in Shortfield for a century, in the midst of the municipality and indeed also within the roams of the school’s professional work – with the teachers well aware of the continuous history – but with only people from the outside realising the problem of racism in Shortfield.
Taking Stock of the Evidence for the Gender-Equality Paradox in Gendered Names: A Reply to Berggren (2023) with New Data
Authors: Vishkin Allon
Published: April 2023

A phonetic feature called voicing has been shown to reflect the gendering of names. Vishkin et al. leveraged this insight to examine gender differentiation as a function of increasing gender equality, both across historical time and across the 50 United States. In this reply, I address a wide range of criticisms raised by Berggren on these findings. I begin by presenting novel data from 76+ million baby names in France from 1900 to 2021. Findings converge with Berggren’s conclusion that the historical trend of voicing of female names is nonlinear and therefore cannot be fully accounted for by the monotonic increase of gender equality. However, I show the state-level analysis is robust to his critiques. I conclude that there are more gendered names in more gender-equal societies at the state level, even though the historical data does not shed light on the historical development of this phenomenon.
Influence of Company Characteristics on Earnings Management in Group Affiliated and Standalone Firms: Evidence from India
Authors: Isha  , Mangala Deepa
Published: April 2023

The study investigates the influence of company-specific characteristics, such as firm age, firm size, performance, leverage, capital intensity ratio, and assets growth, on earnings management. The study also examines the influence of such characteristics on earnings management in group-affiliated and standalone firms. The final sample consists of 248 companies listed on the Bombay Stock Exchange. The research takes place from 2012–2013 to 2018–2019. Signed discretionary accruals and signed discretionary current accruals are used as proxies for measuring earnings management. The findings show that the firm’s age, performance, and leverage are all positively associated with signed discretionary accruals. However, the capital intensity ratio has a negative relationship. Further, group firms are less likely to indulge in earnings management practices as compared with standalone firms. Also, the firm age and performance have positive relation, and capital intensity ratio has negative relation with signed discretionary accruals for group firms. In the case of standalone firms, firm size, performance, and leverage have a positive association whereas capital intensity has a negative association. The results of the present study give insight to financial analysts, regulators, investment analysts, credit rating agencies, etc., to keep an eye on manipulative reporting practices done by companies of different characteristics and ownership attribute.
Patients’ Trust in Health Care Providers Among Hospitalized Patients, Jimma, South West Ethiopia
Authors: Tegenu Lemma Kenenisa , Tilahun Beyene Desalew , Mekoya Jemaneh Tsiyon , Melkamu Andualem Eneyew , Atomsa Hunde Gemechu
Published: April 2023

Introduction

Trust is a fundamental aspect of the patient–health care provider (HCP) relationship associated with adherence to medical treatment and continuity of follow-up. Despite its importance there is a paucity of information in Ethiopia.

Objectives

This study aimed to assess patient trust in HCPs at the Jimma medical center (JMC), Ethiopia.

Methods

An institution based cross-sectional study was conducted among 404 participants from April 16 to June 29, 2020. Study participants were selected using a systematic sampling technique. Data were collected on socio-demographic characteristics, health related and clinical characteristics, and patient trust in the patient–HCP. The collected data were entered into Epi-Data version 3.1 then exported to SPSS version 23.0 for analysis. Variables with a p-value <.25 on bivariate analysis were considered as candidates for multivariate analyses. Statistical significance on multivariable analysis was declared with p-value < .05 and 95% confidence intervals (CI).

Results

In our study, 38% of patients had low trust. Among the 397 study participants, 46.6% were female. One-third (33.2%) of respondents had no formal education. Patients who live alone [(AOR) 4.30(1.98–9.33), p = .00], and self-reported as a poor current health status [(AOR) 2.32(1.39–3.88), p = .002] were positively associated to patient trust in patient–HCP. On the other hand, duration of disease more than one year after diagnosis [(AOR) 0.48 (0.25–0.92), p = .028], comorbid disease [(AOR) 0.39(0.22−0.67), p = .001], and impaired physical mobility [(AOR) 0.27(0.16−0.45), p = .001] were negatively associated with patient trust in HCP.

Conclusion

This study pinpoints that 38 out of 100 patients had low trust. Living alone and having poor self-reported current health status increased low trust. This calls for HCPs to rebuild trust and give due attention to patients living alone and with poor health status.
Managing respiratory muscle weakness during weaning from invasive ventilation
Authors: Bureau Côme , Van Hollebeke Marine , Dres Martin
Published: April 2023

Weaning is a critical stage of an intensive care unit (ICU) stay, in which the respiratory muscles play a major role. Weakness of the respiratory muscles, which is associated with significant morbidity in the ICU, is not limited to atrophy and subsequent dysfunction of the diaphragm; the extradiaphragmatic inspiratory and expiratory muscles also play important parts. In addition to the well-established deleterious effect of mechanical ventilation on the respiratory muscles, other risk factors such as sepsis may be involved. Weakness of the respiratory muscles can be suspected visually in a patient with paradoxical movement of the abdominal compartment. Measurement of maximal inspiratory pressure is the simplest way to assess respiratory muscle function, but it does not specifically take the diaphragm into account. A cut-off value of −30 cmH2O could identify patients at risk for prolonged ventilatory weaning; however, ultrasound may be better for assessing respiratory muscle function in the ICU. Although diaphragm dysfunction has been associated with weaning failure, this diagnosis should not discourage clinicians from performing spontaneous breathing trials and considering extubation. Recent therapeutic developments aimed at preserving or restoring respiratory muscle function are promising.
Comparative transcriptome analysis of juniper branches infected by Gymnosporangium spp. highlights their different infection strategies associated with cytokinins
Authors: Shao Chenxi , Tao Siqi , Liang Yingmei
Published: April 2023

Background

Gymnosporangium asiaticumandG. yamadaecan shareJuniperus chinensisas the telial host, but the symptoms are completely different. The infection ofG. yamadaecauses the enlargement of the phloem and cortex of young branches as a gall, but not forG. asiaticum, suggesting that different molecular interaction mechanisms exist the twoGymnosporangiumspecies with junipers.

Results

Comparative transcriptome analysis was performed to investigate genes regulation of juniper in responses to the infections ofG. asiaticumandG. yamadaeat different stages. Functional enrichment analysis showed that genes related to transport, catabolism and transcription pathways were up-regulated, while genes related to energy metabolism and photosynthesis were down-regulated in juniper branch tissues after infection withG. asiaticumandG. yamadae. The transcript profiling ofG. yamadae-induced gall tissues revealed that more genes involved in photosynthesis, sugar metabolism, plant hormones and defense-related pathways were up-regulated in the vigorous development stage of gall compared to the initial stage, and were eventually repressed overall. Furthermore, the concentration of cytokinins (CKs) in the galls tissue and the telia ofG. yamadaewas significantly higher than in healthy branch tissues of juniper. As well, tRNA-isopentenyltransferase (tRNA-IPT) was identified inG. yamadaewith highly expression levels during the gall development stages.

Conclusions

In general, our study provided new insights into the host-specific mechanisms by whichG. asiaticumandG. yamadaedifferentially utilize CKs and specific adaptations on juniper during their co-evolution.