bluuebunny/crossref_metadata_2025 huggingface dataset:
Severe Corrosive Injury Secondary to Chlorine Bleach Ingestion: A Case Report
Authors: Choi Yonghoon
Published: December 2024

Corrosive injuries to the upper gastrointestinal tract, particularly those caused by alkaline substances, often result in more severe and deeper tissue injuries than those observed after ingestion of acidic substances. We report a case of severe corrosive injury following ingestion of chlorine bleach (200 mL), an alkaline agent. Initial endoscopic evaluation revealed severe esophageal and gastric injuries with necrosis (Zargar grade 3b), without any signs of perforation. The treatment plan included prolonged fasting with total parenteral nutrition, and enteral feeding was initiated via jejunostomy 1 month after hospitalization. The patient was hospitalized and discharged on several occasions until we observed complete healing of the esophagus and stomach. Follow-up endoscopy performed 4 months after the injury showed improvement in the esophageal wall; however, severe stenosis prevented oral intake. Therefore, the patient underwent surgical intervention, including esophagectomy, total gastrectomy, and esophagocolojejunostomy, 7 months post-injury. Since the initial surgery, the patient underwent repeat wound revision procedures, percutaneous drainage, reconstruction, and bougienation owing to anastomotic leakage, infection, and stenosis for approximately a year. The patient received oral and jejunostomy tube feeding for approximately 2.5 years after the initial injury. Early endoscopy was useful to confirm the severity and predict the prognosis of corrosive injuries in this case. Severe corrosive injuries following ingestion of alkaline substances are associated with poor clinical prognosis, as anticipated. Caution is warranted for the diagnosis and treatment of this condition.
Gastric Ulcer Bleeding Caused by Systemic Inflammatory Response to Mycobacterial Bacteremia
Authors: Synn Soo Bin , Kim Su Jin
Published: December 2024

Adipose-derived stem cells are gaining attention because they are easily obtained in large quantities. However, concerns about side effects of their use have also been raised. Mycobacterial infections can develop during stem cell treatment in the event of incomplete medical device sterilization and/or suboptimal hygiene during cell processing and culture. In general, mycobacterial infections most frequently manifest as pneumonia; however, infections of the bones, lymph nodes, skin, soft tissues, and blood also occur. Mycobacterial bacteremia occurs relatively frequently, but cases of gastric ulcers induced as a complication of stem cell treatment and subsequent mycobacterial bacteremia have not been reported. Herein, we report a 75-year-old man who developed mycobacterial bacteremia and gastric ulcers following adipose-derived stem cell injection. This case report raises awareness of the possibility of Mycobacterium abscessus complex bacteremia and subsequent gastric ulcer bleeding—a rare complication of stem cell therapy.
An investigation of Agriculture Knowledge Sharing through Indigenous Communication Systems: Insights from Ethnic Communities
Authors: Gogoi Bidyut P. , Ansari M. N. , Kumar Birendra , Sirilakshmi Yasa , T Ashwini , Saikia Dipankar
Published: December 2024

Developing countries like India are having latest methods of communication, but their effective utilization by people who are less exposed is doubtful. In rural areas indigenous means of communication still play a vital role in social functioning, maintenance and social change. A study was employed with a qualitative research design to explore the indigenous communication systems of four ethnic communities (Ahom, Kachari, Mising and Deori) in Dhemaji district of Assam. The total respondents for the study was one hundred (100) comprising both male and female to capture gender-specific roles in agricultural communication. Focus group discussions, interviews, and auto-ethnographic observations were employed, ensuring a participatory approach to collect data from four selected villages across two culturally diverse blocks. Findings reveal that folk songs such as Bihu songs, Oi-nitom, and Bisugeet encapsulate agricultural processes and seasonal transitions, ensuring the preservation and transmission of traditional knowledge. The rituals like Narasiga Sabah, Nakathia Sisha, and Guch Luwa not only serve as cultural markers but also communicate critical agricultural practices to farmers. Similarly, proverbs and riddles acted as mnemonic devices for agricultural techniques and ecological wisdom. The study concludes that integrating these indigenous practices with modern extension systems can significantly enhance rural communication strategies. The findings of the present study hold a great potential in the field of communication for development research as well as for planning and dissemination of need based information among rural families for agricultural development that elevate sustainable rural livelihoods.
Application of Extreme Value Theory in Predicting Floods in Region 3, Zimbabwe
Authors: Ever Moyo , Silvanos Chirume
Published: December 2024

The use of Extreme Value Theory to predict the possibility of floods has advanced our understanding of the occurrence of this rare phenomenon. The main goal of this research is to use the Block Maxima technique of the Extreme Value Theory on annual maximum rainfall to predict the occurrence of floods by estimating the probability and intensity of future flooding events. The Extreme Value Theory is more suitable for predicting floods because it focuses on extreme events, providing better accuracy for rare and high-magnitude occurrences. Unlike traditional methods, the Extreme Value Theory handles outliers effectively and models tail behaviour which is crucial for understanding flood risks. It also adapts well to non-stationary conditions like climate change, while traditional methods assume past conditions will repeat. The annual maximum rainfall data used in this research came from the Meteorological Services Department of Zimbabwe in Harare, Zimbabwe. It covered five "convenience sampled" provinces in the purposefully sampled natural Region 3, Zimbabwe. The regions include the Midlands, Mashonaland East, Manicaland, Masvingo and Matabeleland South. We applied the Maximum Likelihood Estimation Method on the annual maximum rainfall data to estimate the Generalised Extreme Value parameters which were used to estimate the return levels and return period. The return level plots and chi-square distribution were used to assess the model fit. The results showed that the return level for a 200-year flood event is 1685.13mm, with a return period of 200years.The forecast results showed that the magnitude of annual maximum rainfall increases with time, suggesting a high risk of flooding. Hence, early warnings and preparedness, risk assessment and management can help control or lessen flooding in the future while saving the environment and providing humanitarian aid in times of need.
Evaluation of Drinking Water Quality in Hospitals: A Study from Ranchi, Jharkhand, India
Authors: Xalxo Shreya Maria , Paliwal Harsh Bodh
Published: December 2024

Water is one of the natural resources, which are found in an adequate amount. It is an essential source for the existence of life on the planet earth. Water plays an important role in our health. It helps in bringing nutrient to cells, getting rid of wastes, protecting joints and organs and maintaining our body temperatures. Water supply to healthcare facilities is frequently an overlooked yet essential for safe patient care and can be manageable source of infections. This paper presents a study in drinking water quality of different hospitals in which 8 water samples from three government hospitals and five private hospitals were collected in Ranchi district (total 8) and were analyzed for 10 physio – chemical parameters such as pH, Electrical conductivity, Temperature, Alkalinity, Chloride, Total hardness, Calcium hardness, Magnesium hardness, Turbidity and Total dissolved solids. All the water samples were within the permissible limits stated by both BIS and WHO.
Genetic Diversity of the Methicillin-resistant Staphylococcus aureus Isolates Circulating in Fako Division, South West Region, Cameroon
Authors: Keneh Nene Kaah , Esemu Seraphine Nkie , Tendongfor Nicholas , Ndip Lucy Mande
Published: December 2024

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of hospital- and community-associated infections impacting national and global health. In recent years, MRSA has been detected in livestock species and their products. WHO has MRSA among the top 24 priority pathogens in 2024, posing the greatest threats to human health.
Aim: To characterise the SCCmec elements and investigate the genetic diversity of MRSA strains recovered from different sources in Fako.
Study Design: A laboratory-based cross-sectional study.
Place and Duration: Department of Microbiology and Parasitology, Faculty of Science, University of Buea, and Laboratory for Emerging Infectious Diseases, University of Buea, between June 2022 and September 2024.
Methodology: The study characterised 76 MRSA strains from diverse sources in Fako to identify the SCCmec types by conventional and multiplex PCR assay. Additionally, the mecA gene amplicons of some strains was sequenced. The sequences were analysed and uploaded to the NCBI-Genbank.
Results: SCCmec type IV was most prevalent (57.9%), followed by type V (21.1%). All the sequences revealed high sequence identity when compared to those available on NCBI using the BLASTN. The sequences showed significant genetic similarity, ranging from 99.1% to 100% for the nucleotides and 98.6% to 100% for the amino acids. Compared with reference sequences retrieved from GenBank, similarity ranged from 98.2% to 100% and 97.9% to 100%, respectively.
Conclusion: Detecting diverse SCCmec types in the MRSA strains denotes the complexity of MRSA epidemiology in Fako. Our findings indicate a risk for the transmission of MRSA across different sources, thus highlighting the need for a One Health approach to MRSA prevention and control. GenBank assigned the accession numbers OP042343 to OP042352 for HA-MRSA, OP042356 to OP042361, OP042363, and OP716861 to OP716868 for LA-MRSA, and OP716859 to OP716860 for CA-MRSA were assigned.
Green Synthesis and Characterization of Silver-copper Bimetallic Nanoparticles Using Alternanthera brasiliana Stem Extract
Authors: Adhikari Safal , Subedee Anup , Bhattarai Deval Prasad , Oli Hari Bhakta , Shrestha Ram Lal (Swagat)
Published: December 2024

The green synthesis of bimetallic silver copper nanoparticles (Ag-CuNPs) has gained attention due to their broad applications. Here, Ag-Cu bimetallic nanoparticles were synthesized using an aqueous extract from the stem of Alternanthera brasiliana. The phytochemical composition of the extract was evaluated through standard phytochemical tests, and the formation of nanoparticles was tracked using UV-visible spectroscopy. The resulting nanoparticles were further characterized using Fourier Transform Infrared (FTIR) spectroscopy, and X-ray diffraction (XRD). Using the Debye-Scherrer formula to interpret XRD data, the estimated sizes of the silver, copper, and silver-copper nanoparticles were 11.81 nm, 55.33 nm, and 12.45 nm, respectively, all synthesized under comparable conditions. Additionally, the antimicrobial properties of these nanoparticles were evaluated, revealing significant activity against various selected microorganisms. The study highlights an eco-friendly approach for synthesizing Ag-CuNPs with promising antimicrobial potential.
Effect of Different Weed Management Practices on Growth, Yield and Economics of Kharif Grain Sorghum [Sorghum bicolor (L.) Moench]
Authors: Akash M. , Krishnamurthy D. , Ramesha Y. M. , Ajayakumar M. Y. , Ravi S.
Published: December 2024

A field experiment was conducted during the kharif season of 2023 at the Agricultural Research Station in Hagari, Ballari, to assess the effect of different weed management practices on the growth and yield of kharif grain sorghum. The experiment was replicated thrice in randomized complete block design comprising of eleven different treatments. According to the findings, the growth parameters like plant height (138.8 cm), number of leaves per plant (8.9), leaf area (29.1 dm2 plant-1), leaf area index (4.31) and total dry matter production (212.3 g plant-1) at harvest recorded significantly higher with the application of atrazine 50% WP @ 500 g a.i. ha-1 as PE fb metribuzin 70% WP @ 100 g a.i. ha-1 as PoE at 15-18 DAS (T7) treatment. This treatment also recorded higher grain yield (2905 kg ha-1), stover yield (8576 kg ha-1), harvest index (25.3%), gross returns (Rs. 1,19,425 ha-1), net returns (Rs. 80,988 ha-1) and B:C (3.11) when compared with other treatments. Which might be due to, application of atrazine as pre-emergent control weeds in earlier stages of crop and post-emergent application of metribuzin control weeds in later stages of crop growth. The application of atrazine and metribuzin helps in better growth of plant and obtaining the higher grain yield, net returns and B:C found economically feasible.
Shrinking of the Aral Sea: Causes, Effects, Possibilities of Revitalization
Authors: Jabbarov Zafarjon , Abdrakhmanov Tokhtasin , Makhammadiev Samad , Nomozov Urol , Abdullaev Shokhrukh , Imomov Otamurod , Sultanova Nodirabonu , Wiłkomirski Bogusław
Published: December 2024

The Aral Sea, which a few dozen years ago was the fourth largest lake in the world, currently exists only in a rudimentary form. The drastic reduction in the flow of water from the two great rivers feeding the Aral Sea, caused by the Soviet plan to irrigate cotton-growing areas, caused enormous economic, social and health problems and a decline in biodiversity. The main natural consequences of disturbing the water balance are: a significant decrease in biodiversity, local climate changes, an increase in the salinity of remaining waters and dry bottom soils. The social consequences discussed include: the decline of fishing and fish processing and the disappearance of tourism, which results in unemployment and increased poverty of the local population. A very important problem are dust storms that arise on a dry bottom and spray salty and toxic dust throughout the Aral Sea basin, which results in different negative health effects for the people living there. The article also discusses the possibilities of minimizing the price paid for shrinking a large body of water. A return to the pre-1960 state is very unlikely in the foreseeable future, but a relatively simple, although partial, solution to the problem, is to reduce soil erosion by introducing vegetation. The research proposed and conducted by a group from the National University of Uzbekistan is aimed at correlating soil parameters with the possibilities of effectively introducing plants into existing habitats. The importance of the selection of species was pointed out not only because of their adaptation possibilities, but also because of their economic importance and phytoremediation possibilities.
„Vergangenheit, Gegenwart und Zukunft der Finanzgerichtsbarkeit“ – Symposium anlässlich des 75-jährigen Bestehens des Niedersächsischen Finanzgerichts
Authors: Mönninghoff Martin Ludger , Teuber Carina , Wuthenow Matthias
Published: December 2024

Anlässlich des 75-jährigen Bestehens des Niedersächsischen Finanzgerichts richtete dessen Richterschaft gemeinsam mit dem Verein zur Förderung der Steuerrechtswissenschaft an der Leibniz Universität Hannover (VFS Hannover) am 13.8.2024 ein Symposium zum Thema „Vergangenheit, Gegenwart und Zukunft der Finanzgerichtsbarkeit“ aus.
Überblick über wesentliche Änderungen im Bereich der Unternehmensumstrukturierungen im Rahmen des JStG 2024 – Teil I
Authors: Krüger Sebastian , Petersen Nils
Published: December 2024

Das in der Finanzausschussfassung am 18.10.2024 vom Bundestag verabschiedete (BT-Drucks. 20/13419) und nach Übermittlung an den Bundesrat mit Gesetzesbeschluss vom 1.11.2024 (BR-Drucks. 529/24) am 22.11.2024 vom Bundesrat bestätigte (BR-Drucks. 529/24 [Beschluss]) Jahressteuergesetz 2024 (JStG 2024) enthält eine Vielzahl gesetzlicher Änderungen im Bereich der Unternehmensumstrukturierung. Hierzu zählen neben den umwandlungssteuer- ebenso einkommensteuer- und körperschaftsteuerrechtliche Normen. Der vorliegende Beitrag soll einen Überblick über diese Änderungen geben und darüber hinaus einzelne Bestandteile kritisch hinterfragen. Dabei werden auch die im Verlauf des Gesetzgebungsverfahrens vorgeschlagenen und teilweise umgesetzten Änderungen dargestellt. Teil I konzentriert sich auf die wesentlichen Änderungen der einkommensteuerrechtlichen Normen. In Teil II werden die Änderungen im Umwandlungssteuergesetz und im Körperschaftsteuergesetz erörtert.
Game Theoretical Perspectives On Dual-Channel Closed Loop Supply Chain With A Reward-Driven Remanufacturing Policy
Authors: Kundu Soumita
Published: December 2024

This paper evaluates the impact of reward driven remanufacturing policy and pricing schemes on the dualchannel supply chain competition. In the proposed model, a manufacturer sells products both through a retailer
and directly to end users in the forward supply chain. In the reverse supply chain, the manufacturer collects
used products to remanufacture them into new ones. Mathematical models for the supplier Stackelberg, retailer Stackelberg, Nash game, and centralized scenarios are developed to define pricing decisions and remanufacturing strategies. The optimality of all proposed models is analyzed theoretically
Questionnaire-Based Study On Post Anaesthesia Visits In Tertiary Hospital
Authors: Reddy Katta Dinesh Chandra , N Dr. Kiran.
Published: December 2024

Background In recent years, significant advancements in anesthesiology have led to better healthcare services
and a reduction in surgical complications.1 While much research has been conducted on the practical application
of anesthesia, little attention has been given to patient satisfaction.2 According to recent reports, only 22% of
anesthesiologists provide post-anesthesia visits on a daily or weekly basis. However, studies show that hospitals
that offer post-anesthesia visits tend to have higher patient numbers, indicating the importance of this service.
Anesthesiologists who do not perform post-anesthesia visits often cite reasons such as lack of time, patient
dismissal, or lack of interest.3 But by providing this service, anesthesiologists can improve patient satisfaction
and ensure that patients receive the best possible care. I selected this study to investigate the reasons for the lack
of post-operative visits
Materials and Methods: In this study, a questionnaire of 11 questions was sent via email to consultant
anaesthetists and anaesthesia post graduates of different medical colleges across India, after obtaining consent
from the participants. These questions were prepared on a google form. The questionnaire was sent to 10
anaesthesiologists who have validated it and the Cronbach’s alpha for the questionnaire is 0.82.
Results: The practice of PAVs among anesthesiologists was assessed and observed that 57.3% of the
anesthesiologists do not practice PAVs, and 42.6% reported that they perform PAVs.The majority of the
anesthesiologists who do not practice PAVs reported that lack of time the most common reason for not performing
PAVs regularly (80.4%) followed by long distances to the patients to be covered (19.6%), patients already
discharged (18.6%) extensive search (17.5%) and others (13.4%).
Conclusion: It is observed that most anesthesiologists do not practice PAVs. However, post-anesthesia visits by anesthesiologists are highly appreciated, and they play an essential role in detecting postoperative complications.
Music: A Mellow Out For Mechanical Ventillated Patients
Authors: K.N Ashwini , Lobo Dr. Diana
Published: December 2024

Music therapy holds significant promise as a complementary intervention in the ICU. Its ability to reduce
anxiety, manage pain, improve physiological parameters and provide emotional support makes it a valuable
addition to the care of critically ill patients with mechanical ventilation. As the body of evidence supporting its
benefits continues to grow, music therapy has become an integral part of holistic ICU care, offering healing
and hope beyond traditional medicine. Music can serve as a distracter by diverting attention away from an
unpleasant stimulus. Musical compositions are complex blends of organized sound and is universally valued
for its therapeutic properties which invokes both psychological and physiological responses within the listener.
The physiological responses to music occur as music passes through the auditory cortex to the limbic system,
affecting the ANS, which controls the cardiovascular, respiratory, neuroendocrine, and immune systems of the
body. Music produces psychological responses by engaging the right hemisphere of the brain, which is involved
in intuitive and creative methods of processing information. From the auditory cortex, music is processed in the
limbic system known as the center of emotions, sensations, and feelings where by it impacts on individual’s
emotional state.
Conclusion: To improve the patient care and health related quality of life in mechanical ventilated patients,
nurses need to use music therapy as interventions to place individuals in the best possible environment to
promote health, healing, and restoration. This concept paper describes the various therapeutic mechanisms of music and discusses the physiological, psychological and hormonal effects of music on mechanical ventilated patients
“A Study To Assess The Effectiveness Of Structured Teaching Programme On Knowledge Regarding Early Ambulation On Laparoscopic Cholecystectomy Patients In Apollo Speciality Hospitals, Jayanagar, Bangalore (India).”
Authors: MS Mr. Hareesh , Joseph Ms. Sheeja , Sharma Ms. Rohini
Published: December 2024

Laparoscopic cholecystectomy is the treatment of choice for gall bladder stone disease. Difficult cholecystectomy
is associated with serious complications and a high conversion rate. The aim of this study was to review the
current strategies to manage difficult cholecystectomy.
Bile duct injuries were analysed in a prospective study of 1,250 cases of laparoscopic cholecystectomy. The aim
of the study was to identify the incidence and causes of bile duct injuries in the course of laparoscopic
cholecystectomy, and to recommend the possible ways to avoid this serious complication. All injuries were
attributed to distortion of Calot’s triangle and failure to clearly identify the anatomy. A recent history of acute
cholecystitis, a history of jaundice, pancreatitis and repeated or technically difficult endoscopic retrograde
cholangio-pancreatography (ERCP) were associated with local inflammatory changes that had possibly
contributed to the distorted anatomy at Calot’s triangle and consequently to the injury. All injuries were detected
during surgery and immediately repaired. Major bile duct injuries were repaired by choledocho-enterotomy,
while minor injuries were treated by simple sutures around the T tube in the common bile duct. All patients were
asymptomatic with normal liver function tests on follow-up for a period up to 3 years after
surgery. Conclusions: The incidence of bile duct injuries in laparoscopic cholecystectomy is comparable to open
surgery. Patients with a clinical history of acute cholecystitis, or a recent history of jaundice and repeated ERCP
should be considered for operative cholangiography in order to help reduce the chances of bile duct injuries.
Materials and Methods:
A Pre-experimental and one group pretest and posttest design was used to assess the knowledge on early
ambulation of 50 patients on Laparoscopic Cholecystectomy. A structured questionnaire was developed to assess
the knowledge of the patients. The study started with the pretest followed by structured teaching program and
posttest.
Results:
The post test showed a significant improvement in the knowledge regarding Early Ambulation of laparoscopic
Cholecystectomy patients. In the pretest 20 patients had good level of knowledge and 30 had average level of
knowledge. The post test revealed that 40 patients had Very good knowledge and 10 had good level of knowledge.
Paired t-test value of knowledge and practice was 2.06 and 1.47 respectively, which was higher than the table
value 2.66* at p <0.05 hence the structured teaching program was found to be effective in improving the knowledge of the patients. Conclusion: Patients acquired knowledge laparoscopic cholecystectomy. Also have an improvement in diet, exercise to prevent other complications.
Saúde Da Mulher E Igualdade De Gênero: Perspectivas Jurídicas Para A Luta Contra O Feminicídio
Authors: Braz Laís Müller Napoleão , Araújo Maria Emilly Rodrigues , Oliveira Luiz Fernando De , Lima Eva Rafaela Pinto , Cunha Frederico Rotta Da
Published: December 2024

A pesquisa teve como objetivo analisar as perspectivas jurídicas para o combate ao feminicídio e suas
implicações na saúde da mulher, buscando mapear lacunas na legislação e nas políticas públicas, além de avaliar
a eficácia das medidas implementadas. Utilizou-se uma abordagem bibliográfica, envolvendo a análise de obras,
artigos e documentos relevantes sobre o tema, com levantamento realizado em plataformas acadêmicas e
repositórios brasileiros. Os resultados revelaram a complexidade do feminicídio e da violência de gênero,
evidenciando que, embora existam avanços legislativos, como a Lei Maria da Penha e a tipificação do
feminicídio, ainda há falhas na proteção das mulheres e na articulação entre saúde e direito. A pesquisa destacou
a necessidade de um arcabouço jurídico mais robusto, além de boas práticas que possam ser replicadas em
diferentes contextos, e ressaltou a importância de campanhas de conscientização e educação para transformar a cultura de violência. Conclui-se que o combate ao feminicídio e à violência de gênero é uma responsabilidade
Economia Circular Como Mecanismo De Resposta Às Mudanças Climáticas
Authors: Bernardy Tatiane Atanásio Dos Santos , Freitas Claudio Luiz De , Cerqueira Homero De Giorge , Nascimento Deise Mara Do , Vieira Douglas Caetano
Published: December 2024

O objetivo desta pesquisa foi investigar como a adoção de práticas de economia circular pode contribuir para o
enfrentamento das mudanças climáticas, analisando suas potencialidades e desafios. A pesquisa adotou uma
abordagem qualitativa e exploratória, com uma amostra composta por 32 ambientalistas, e a coleta de dados foi
realizada por meio de entrevistas em profundidade. Os resultados indicaram que, embora a economia circular
ofereça soluções significativas para a redução das emissões de gases de efeito estufa e a conservação dos recursos
naturais, sua implementação enfrenta obstáculos como a falta de infraestrutura adequada, as barreiras
econômicas e a necessidade de uma mudança cultural no consumo. Além disso, os entrevistados destacaram a
importância da inovação tecnológica, das políticas públicas de incentivo e da colaboração entre governos,
empresas e sociedade para garantir a eficácia da transição para um modelo econômico mais sustentável. A
pesquisa conclui que, embora existam desafios a serem superados, as oportunidades oferecidas pela economia
circular são substanciais e devem ser exploradas de forma integrada, com foco na criação de soluções inovadoras e no engajamento de todos os setores da sociedade, para que a economia circular seja efetivamente um mecanismo de resposta às mudanças climáticas.
Saúde Da Mulher: Mecanismos E Medidas Legais Para A Igualdade De Gênero
Authors: Ferreira Rogério Campos , Costa Pedro Vitor Lopes , Lisboa Marcos Vinicius , Costa Luana Maria Araújo , Leite Kelly Josiane Oliveira Lustosa
Published: December 2024

Esta pesquisa teve como objetivo explorar as perspectivas e experiências de profissionais da Delegacia
Especializada de Atendimento à Mulher (DEAM) no enfrentamento da violência de gênero, especialmente o
feminicídio, e na promoção da saúde da mulher. Adotando uma abordagem qualitativa e exploratória, a pesquisa contou com uma amostra de 15 profissionais da DEAM, incluindo delegados, agentes de polícia, assistentes sociais e psicólogos. A coleta de dados foi realizada por meio de entrevistas semiestruturadas, e os dados foram analisados com base na técnica da análise do discurso. Os resultados revelaram que, apesar de avanços legislativos, como a Lei do Feminicídio, o sistema de justiça ainda enfrenta desafios significativos, como a impunidade, a morosidade judicial e a falta de integração entre os serviços de saúde, segurança e justiça. A saúde mental das vítimas também foi identificada como uma questão crucial, com lacunas no atendimento psicológico adequado. Além disso, a pesquisa evidenciou a persistência de estereótipos de gênero que impactam o atendimento e a necessidade de uma rede mais integrada e eficaz de apoio às mulheres. Em conclusão, a pesquisa ressaltou que, para o enfrentamento efetivo do feminicídio, é fundamental a melhoria das políticas públicas, o fortalecimento da capacitação profissional, a integração dos serviços de atendimento e a promoção de uma mudança cultural em relação à violência de gênero
Revolucionando O Cuidado Com A Pele: O Papel Do Microbioma No Controle De Inflamações Crônicas
Authors: Martin Natalia
Published: December 2024

O microbioma cutâneo - uma complexa comunidade de microrganismos que vive na superfície da pele - tem
emergido como um elemento central na saúde dermatológica e no tratamento de inflamações crônicas, como
dermatite atópica, psoríase, rosácea e acne. Pesquisas recentes têm demonstrado que o equilíbrio entre as
diversas espécies microbianas é essencial para a manutenção da barreira cutânea, a regulação da resposta
imunológica e a proteção contra patógenos oportunistas. O desequilíbrio no microbioma, conhecido como
disbiose, está diretamente associado ao aumento de processos inflamatórios e à piora de condições cutâneas,
conforme relatado por estudos como os de Sanford et al. (2016) e Egert et al. (2020). Essa compreensão tem
impulsionado o desenvolvimento de terapias inovadoras, como probióticos tópicos, prebióticos e pós-bióticos,
que buscam restaurar a microbiota saudável e modular a inflamação. Além disso, intervenções dietéticas e
mudanças no estilo de vida têm sido exploradas como formas de influenciar positivamente o microbioma da pele.
Tecnologias avançadas, como análises genômicas e metagenômicas, têm permitido uma abordagem mais precisa
e personalizada no tratamento de condições inflamatórias crônicas, identificando os perfis microbianos
individuais de cada paciente. Embora o potencial terapêutico do microbioma cutâneo seja promissor, ainda
existem desafios, como a padronização de métodos para avaliação da microbiota e a compreensão das interações
entre os microrganismos e o sistema imunológico da pele. Este artigo explora as evidências científicas mais
recentes sobre o papel do microbioma no controle de inflamações crônicas e discute como essas descobertas
estão revolucionando o campo da dermatologia, possibilitando a criação de tratamentos mais eficazes, seguros e personalizados, que não apenas tratam os sintomas, mas também atuam na causa subjacente das doenças inflamatórias cutâneas
Tourism Concepts And Rural Tourism In Portugal
Authors: Fernandes Joel Barros , Albuquerque Eduardo Barbas De , Silva Amândio F. C. Da
Published: December 2024

Objective: To systematize literature on tourism and tourism in rural areas in Portugal.
Methodology: Review of literature on tourism and tourism in rural areas in Portugal that leads us to the
respective concepts.
Results: Tourism in Portugal could reach approximately 39.5 billion euros in 2024, which will represent around
17.4% of the Gross Domestic Product. Rural and nature tourism in Portugal is a practice that values the wellbeing of visitors and promotes environmental conservation. Conclusions: Tourism in Portugal follows a trend of growth and massification and tourism in rural areas seeks to be an alternative to the aforementioned massification
Development And Evaluation Of A Vegetable Drink Based On Rice Milk, Quinoa And Passion Fruit Pulp
Authors: Campos Vitória Alves , Araújo Gian Marcos Dias , Silva Juliana Moreira Da , Carvalho Nelson Pereira , Viroli Sérgio Luis Melo
Published: December 2024

A portion of the Brazilian population has an inability to digest, metabolize, or absorb food or some of its nutrients.
Lactose intolerance is a disorder that occurs at all ages. Lactose-free products are a necessity to meet the needs
of individuals who suffer from this disorder. Due to the demand for lactose-free foods, a plant-based beverage
based on rice milk, quinoa, and flavored with passion fruit was developed as a nutritional beverage option.
Formulations (F1, F2, and F3) were developed by varying the amounts of rice and quinoa and fixing the amounts
of passion fruit pulp, water, and sucrose. The physicochemical analysis followed the physicochemical methods
for food analysis of the Adolfo Lutz Institute and the microbiological analysis followed the Manual of Methods
for Microbiological Analysis of Foods. In order to verify whether there were significant differences, the ANOVA
analysis of variance was applied using the SISVAR program version 5.6. The Principal Component Analysis
(PCA) was performed with the PAST software. The plant-based beverage made from rice milk, quinoa and passion
fruit pulp had a low lipid index and low ash concentration, an acidic pH and 4.01% of the daily protein intake
required for individuals aged 4 to 8 years. It was produced naturally, without stabilizers, thickeners or industrial
emulsifiers. Its production could be a feasible technological possibility for small manufacturers. The rice and quinoa beverage flavored with passion fruit pulp could be a viable alternative for people seeking a balanced, nutritious diet or for people who are lactose intolerant or allergic to animal milk or soy proteins
Business Strategies For Adapting ToEconomic Recessions
Authors: Walia Ayanna
Published: December 2024

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Conversation Analysis and Affiliation and Alignment
Authors: Steensig Jakob
Published: June 2019

The termsaffiliationandalignmentdescribe two diferent types of collaborative, responsive behavior in interaction. In conversation analytic research, these concepts have been distinguished so that “affiliation” describes collaborative behavior on the “affective” level and “alignment” is used for collaborative behavior on a more “structural” level. “Disaffiliation” and “disalignment” are used for noncollaborative behavior on the same levels. This entry outlines the differences between the two concepts and illustrates them by giving examples of utterances in their interactional contexts that are disaffiliatinganddisaligning, affiliating without aligning, and aligning without affiliating. It further discusses the analytic use of the terms and relates them to other recent concepts and fields of investigation in conversation analysis.
Reliability of CT‐based texture features: Phantom study
Authors: Varghese Bino A. , Hwang Darryl , Cen Steven Y. , Levy Joshua , Liu Derek , Lau Christopher , Rivas Marielena , Desai Bhushan , Goodenough David J. , Duddalwar Vinay A.
Published: June 2019

Objective

To determine the intra‐, inter‐ and test‐retest variability of CT‐based texture analysis (CTTA) metrics.

Materials and methods

In this study, we conducted a series of CT imaging experiments using a texture phantom to evaluate the performance of a CTTA panel on routine abdominal imaging protocols. The phantom comprises of three different regions with various textures found in tumors. The phantom was scanned on two CT scanners viz. the Philips Brilliance 64 CT and Toshiba Aquilion Prime 160 CT scanners. The intra‐scanner variability of the CTTA metrics was evaluated across imaging parameters such as slice thickness, field of view, post‐reconstruction filtering, tube voltage, and tube current. For each scanner and scanning parameter combination, we evaluated the performance of eight different types of texture quantification techniques on a predetermined region of interest (ROI) within the phantom image using 235 different texture metrics. We conducted the repeatability (test‐retest) and robustness (intra‐scanner) test on both the scanners and the reproducibility test was conducted by comparing the inter‐scanner differences in the repeatability and robustness to identify reliable CTTA metrics. Reliable metrics are those metrics that are repeatable, reproducible and robust.

Results

As expected, the robustness, repeatability and reproducibility of CTTA metrics are variably sensitive to various scanner and scanning parameters. Entropy of Fast Fourier Transform‐based texture metrics was overall most reliable across the two scanners and scanning conditions. Post‐processing techniques that reduce image noise while preserving the underlying edges associated with true anatomy or pathology bring about significant differences in radiomic reliability compared to when they were not used.

Conclusion

Following large‐scale validation, identification of reliable CTTA metrics can aid in conducting large‐scale multicenter CTTA analysis using sample sets acquired using different imaging protocols, scanners etc.
Do secondary school students make use of effective study strategies when they study on their own?
Authors: Dirkx Kim Josefina Hubertina , Camp Gino , Kester Liesbeth , Kirschner Paul Arthur
Published: June 2019

Although there is a large body of evidence for the utility of particular study strategies such as retrieval practice and distributed practice as memory‐enhancing instruments, they are seldom used by learners in educational practice. Thus far, the research on the use of these study strategies has focused only on undergraduate university students, oftentimes only investigating a set of predefined strategies. The question, thus, remains whether these results are generalisable to secondary school students. The present study is the first to explore the use of different study strategies by secondary school students. With the use of an open question, 316 secondary school students from three different secondary school levels were asked how they prepare for an exam when they are studying by themselves. The results show that secondary school students use study strategies considered to be suboptimal. In the discussion, we compare our findings with results of previous studies among undergraduate university students.
FtsZ‐Independent Mechanism of Division Inhibition by the Small Molecule PC190723 in Escherichia coli
Authors: Khare Somya , Hsin Jen , Sorto Nohemy A. , Nepomuceno Gabriella M. , Shaw Jared T. , Shi Handuo , Huang Kerwyn Casey
Published: June 2019

While cell division is a critical process in cellular proliferation, very few antibiotics have been identified that target the bacterial cell‐division machinery. Recent studies have shown that the small molecule PC190723 inhibits cell division in several Gram‐positive bacteria, with a hypothesized mechanism of action involving direct targeting of the tubulin homolog FtsZ, which is essential for division in virtually all bacterial species. Here, it is shown that PC190723 also inhibits cell division in the Gram‐negative bacterium Escherichia coli if the outer membrane permeability barrier is compromised genetically or chemically. The results show that the equivalent FtsZ mutations conferring PC190723 resistance in Staphylococcus aureus do not protect E. coli against PC190723, and that suppressors of PC190723 sensitivity in E. coli, which do not generically decrease outer membrane permeability, do not map to FtsZ or other division proteins. These suppressors display a wide range of morphological and growth phenotypes, and one exhibits a death phenotype in the stationary phase similar to that of a mutant with disrupted lipid homeostasis. Finally, a complementing FtsZ–msfGFP fusion is used to show that PC190723 does not affect the Z‐ring structure. Taken together, the findings suggest that PC190723 inhibits growth and division in E. coli without targeting FtsZ. This study highlights the importance of utilizing a combination of genetic, chemical, and single‐cell approaches to dissect the mechanisms of action of new antibiotics, which are not necessarily conserved across bacterial species.
Inkjet Printing of Self‐Supporting and Self‐Contained Structured Objects Onto Liquid Surfaces
Authors: Goedel Werner A. , Gläser Kerstin , Mitra Dana , Thalheim Robert , Ueberfuhr Peter , Hammerschmidt Jens , Baumann Reinhard R.
Published: June 2019

Some applications in miniaturized fabrication like valves or force sensors require self‐supporting structures. These may be generated on top of a solid substrate and separated from it afterwards, but this separation is an additional manufacturing step and may stress the structure. Therefore, it may be of advantage to create the desired objects directly on top of a liquid. Here, it is shown that self‐supporting and self‐contained structures including lines of defined width, full tone squares and delicate structures with non‐uniform line width, edges and openings can be prepared by inkjet printing of a photo‐curable ink onto a water surface followed by irradiation with ultraviolet light and lift‐off. To make this feasible, convection, spreading, and dewetting of the ink from the water surface has to be suppressed by controlling the timing of the irradiation, the mobility of the water surface and the long and short range interactions between the printed ink and the water substrate. These tasks may be achieved via addition of soluble amphiphiles or via spreading of water insoluble amphiphiles or hydrophobized particles onto the water surface prior to printing. Best results are obtained by printing the desired structures onto a water surface that bears a monolayer of hydrophobized particles.
Investigation of Alkali‐Ion (Li, Na, and K) Intercalation in KxVPO4F (x ∼ 0) Cathode
Authors: Kim Haegyeom , Ishado Yuji , Tian Yaosen , Ceder Gerbrand
Published: June 2019

This work compares the intercalation of K, Na, and Li in KxVPO4F (x ∼ 0). The KxVPO4F (x ∼ 0) cathode delivers reversible capacities of ≈90–100 mAh g−1 in K, Na, and Li cells, at an average voltage of ≈4.33 V for K, ≈3.98 V for Na, and ≈3.96 V for Li. This is so far the highest average voltage known for a K‐intercalation cathode. The lower voltage of Li insertion compared to Na is attributable to undercoordinated Li ions in the KxVPO4F (x ∼ 0) framework. While the material shows high rate capability for all the alkali ions, Li migration in KxVPO4F (x ∼ 0) is more difficult than with Na and K. This work suggests that a large cavity is not always good for insertion of alkali ions and cathode materials need to be suitably tailored to each intercalating ion species.
Charge‐Carrier Dynamics, Mobilities, and Diffusion Lengths of 2D–3D Hybrid Butylammonium–Cesium–Formamidinium Lead Halide Perovskites
Authors: Buizza Leonardo R. V. , Crothers Timothy W. , Wang Zhiping , Patel Jay B. , Milot Rebecca L. , Snaith Henry J. , Johnston Michael B. , Herz Laura M.
Published: June 2019

Perovskite solar cells (PSCs) have improved dramatically over the past decade, increasing in efficiency and gradually overcoming hurdles of temperature‐ and humidity‐induced instability. Materials that combine high charge‐carrier lifetimes and mobilities, strong absorption, and good crystallinity of 3D perovskites with the hydrophobic properties of 2D perovskites have become particularly promising candidates for use in solar cells. In order to fully understand the optoelectronic properties of these 2D–3D hybrid systems, the hybrid perovskite BAx(FA0.83Cs0.17)1‐xPb(I0.6Br0.4)3 is investigated across the composition range 0 ≤ x ≤ 0.8. Small amounts of butylammonium (BA) are found that help to improve crystallinity and appear to passivate grain boundaries, thus reducing trap‐mediated charge‐carrier recombination and enhancing charge‐carrier mobilities. Excessive amounts of BA lead to poor crystallinity and inhomogeneous film formation, greatly reducing effective charge‐carrier mobility. For low amounts of BA, the benevolent effects of reduced recombination and enhanced mobilities lead to charge‐carrier diffusion lengths up to 7.7 µm for x = 0.167. These measurements pave the way for highly efficient, highly stable PSCs and other optoelectronic devices based on 2D–3D hybrid materials.
Combined High Catalytic Activity and Efficient Polar Tubular Nanostructure in Urchin‐Like Metallic NiCo2Se4 for High‐Performance Lithium–Sulfur Batteries
Authors: Zhang Chaoqi , Biendicho Jordi Jacas , Zhang Ting , Du Ruifeng , Li Junshan , Yang Xuhui , Arbiol Jordi , Zhou Yingtang , Morante Joan Ramon , Cabot Andreu
Published: June 2019

Urchin‐shaped NiCo2Se4 (u‐NCSe) nanostructures as efficient sulfur hosts are synthesized to overcome the limitations of lithium–sulfur batteries (LSBs). u‐NCSe provides a beneficial hollow structure to relieve volumetric expansion, a superior electrical conductivity to improve electron transfer, a high polarity to promote absorption of lithium polysulfides (LiPS), and outstanding electrocatalytic activity to accelerate LiPS conversion kinetics. Owing to these excellent qualities as cathode for LSBs, S@u‐NCSe delivers outstanding initial capacities up to 1403 mAh g−1 at 0.1 C and retains 626 mAh g−1 at 5 C with exceptional rate performance. More significantly, a very low capacity decay rate of only 0.016% per cycle is obtained after 2000 cycles at 3 C. Even at high sulfur loading (3.2 mg cm−2), a reversible capacity of 557 mAh g−1 is delivered after 600 cycles at 1 C. Density functional theory calculations further confirm the strong interaction between NCSe and LiPS, and cytotoxicity measurements prove the biocompatibility of NCSe. This work not only demonstrates that transition metal selenides can be promising candidates as sulfur host materials, but also provides a strategy for the rational design and the development of LSBs with long‐life and high‐rate electrochemical performance.
Cancer‐Targeting Nanoparticles for Combinatorial Nucleic Acid Delivery
Authors: Vaughan Hannah J. , Green Jordan J. , Tzeng Stephany Y.
Published: June 2019

Nucleic acids are a promising type of therapeutic for the treatment of a wide range of conditions, including cancer, but they also pose many delivery challenges. For efficient and safe delivery to cancer cells, nucleic acids must generally be packaged into a vehicle, such as a nanoparticle, that will allow them to be taken up by the target cells and then released in the appropriate cellular compartment to function. As with other types of therapeutics, delivery vehicles for nucleic acids must also be designed to avoid unwanted side effects; thus, the ability of such carriers to target their cargo to cancer cells is crucial. Classes of nucleic acids, hurdles that must be overcome for effective intracellular delivery, types of nonviral nanomaterials used as delivery vehicles, and the different strategies that can be employed to target nucleic acid delivery specifically to tumor cells are discussed. Additonally, nanoparticle designs that facilitate multiplexed delivery of combinations of nucleic acids are reviewed.