bluuebunny/crossref_metadata_2025 huggingface dataset:
Comprehensive Strategy for Sample Preparation for the Analysis of Food Contaminants and Residues by GC–MS/MS: A Review of Recent Research Trends
Authors: Xu Meng-Lei , Gao Yu , Wang Xiao , Han Xiao Xia , Zhao Bing
Published: October 2021

Food safety and quality have been gaining increasing attention in recent years. Gas chromatography coupled to tandem mass spectrometry (GC–MS/MS), a highly sensitive technique, is gradually being preferred to GC–MS in food safety laboratories since it provides a greater degree of separation on contaminants. In the analysis of food contaminants, sample preparation steps are crucial. The extraction of multiple target analytes simultaneously has become a new trend. Thus, multi-residue analytical methods, such as QuEChERs and adsorption extraction, are fast, simple, cheap, effective, robust, and safe. The number of microorganic contaminants has been increasing worldwide in recent years and are considered contaminants of emerging concern. High separation in MS/MS might be, in certain cases, favored to sample preparation selectivity. The ideal sample extraction procedure and purification method should take into account the contaminants of interest. Moreover, these methods should cooperate with high-resolution MS, and other sensitive full scan MSs that can produce a more comprehensive detection of contaminants in foods. In this review, we discuss the most recent trends in preparation methods for highly effective detection and analysis of food contaminants, which can be considered tools in the control of food quality and safety.
Antioxidant, Scavenging, Reducing, and Anti-Proliferative Activities of Selected Tropical Brown Seaweeds Confirm the Nutraceutical Potential of Spatoglossum asperum
Authors: Tanna Bhakti , Choudhary Babita , Mishra Avinash , Chauhan O. P. , Patel Manish Kumar , Shokralla Shadi , El-Abedin Tarek K. Zin , Elansary Hosam O. , Mahmoud Eman A.
Published: October 2021

Brown seaweeds have shown high potential of bioactivity and provide health benefits as an important functional food ingredient. Therefore, four abundantly growing tropical brown seaweeds—Iyengaria stellata, Spatoglossum asperum, Sargassum linearifolium, and Stoechospermum polypodioides—were collected from the Saurashtra Coast of the Arabian Sea. They were analyzed for metabolite profiling, biochemical activities (including total antioxidant, reducing, scavenging, and anti-proliferative characteristics), and total phenolic and flavonoid contents. A concentration-dependent antioxidant, reducing, and scavenging activities were observed for all four brown seaweeds. The S. asperum and I. stellata extracts showed maximum total antioxidant activity. S. asperum also showed high scavenging and reducing activities compared to other studied brown seaweeds. Further, S. asperum contained high total phenolic and flavonoid content compared to other brown seaweeds collected from the same coast. A multivariate correlation study confirmed a positive correlation between total phenolic and flavonoid contents, and biochemical activities (total antioxidant, scavenging and reducing) for all brown seaweeds. About 35% anti-proliferative activity was observed with S. asperum extract on Huh7 cells; in contrast S. polypodioide showed about 44% proliferation inhibition of Huh7 cells. Similarly, 26% proliferation inhibition of HeLa cells was observed with S. asperum extract. Overall, S. asperum possesses high total flavonoid and phenolic amounts, and showed potential antioxidant, scavenging and reducing characteristics. The study confirmed the nutraceutical potential of S. asperum and that it could be a promising functional food ingredient.
Research Progress in the Multilayer Hydrogels
Authors: Jin Lu , Xu Jia , Xue Youcai , Zhang Xinjiang , Feng Mengna , Wang Chengshuang , Yao Wei , Wang Jinshan , He Meng
Published: October 2021

Hydrogels have been widely used in many fields including biomedicine and water treatment. Significant achievements have been made in these fields due to the extraordinary properties of hydrogels, such as facile processability and tissue similarity. However, based on the in-depth study of the microstructures of hydrogels, as a result of the enhancement of biomedical requirements in drug delivery, cell encapsulation, cartilage regeneration, and other aspects, it is challenge for conventional homogeneous hydrogels to simultaneously meet different needs. Fortunately, heterogeneous multilayer hydrogels have emerged and become an important branch of hydrogels research. In this review, their main preparation processes and mechanisms as well as their composites from different resources and methods, are introduced. Moreover, the more recent achievements and potential applications are also highlighted, and their future development prospects are clarified and briefly discussed.
WDR36-Associated Neurodegeneration: A Case Report Highlights Possible Mechanisms of Normal Tension Glaucoma
Authors: Meer Elana , Aleman Tomas S. , Ross Ahmara G.
Published: October 2021

WDR36 is one of a number of genes implicated in the pathogenesis of adult-onset primary open angle glaucoma (POAG). Here we describe in detail the phenotype of a patient with pathogenic variation in WDR36 who presented with a protracted history of central vision loss. On exam visual acuities were at 20/100 level, had a tritan color defect and showed central arcuate visual field defects on visual field testing. Enlarged cup-to-disk ratios with normal intraocular pressures were associated with severe thinning of the ganglion cell layer (GCL) and retinal nerve fiber layer consistent with a clinical diagnosis of normal tension glaucoma. Full-field electroretinograms revealed a severe inner retinal dysfunction with reduced amplitudes and remarkably delayed timings of the b-wave, but preserved photoreceptor (a-wave) function. The pattern described herein recapitulates some of the findings of an animal model of WDR36-associated POAG and suggests a mechanism of disease that involves a retina-wide inner retinal dysfunction and neurodegeneration beyond the GCL. Further detailed structural and functional characterizations of patients with a pathogenic variant in the WDR36 gene are required to confirm these findings.
Intermittent Hypoxia Alters the Circadian Expression of Clock Genes in Mouse Brain and Liver
Authors: Koritala Bala S. C. , Lee Yin Yeng , Bhadri Shweta S. , Gaspar Laetitia S. , Stanforth Corinne , Wu Gang , Ruben Marc D. , Francey Lauren J. , Smith David F.
Published: October 2021

At least one-third of adults in the United States experience intermittent hypoxia (IH) due to health or living conditions. The majority of these adults suffer with sleep breathing conditions and associated circadian rhythm disorders. The impact of IH on the circadian clock is not well characterized. In the current study, we used an IH mouse model to understand the impact of IH on the circadian gene expression of the canonical clock genes in the central (the brain) and peripheral (the liver) tissues. Gene expression was measured using a Quantitative Reverse Transcription Polymerase Chain Reaction (qRT-PCR). CircaCompare was used to evaluate the differential rhythmicity between normoxia and IH. Our observations suggested that the circadian clock in the liver was less sensitive to IH compared to the circadian clock in the brain.
Identification of Novel Endogenous Controls for qPCR Normalization in SK-BR-3 Breast Cancer Cell Line
Authors: Jain Nityanand , Mitre Ingrida , Nitisa Dina , Pirsko Valdis , Cakstina-Dzerve Inese
Published: October 2021

Normalization of gene expression using internal controls or reference genes (RGs) has been the method of choice for standardizing the technical variations in reverse transcription quantitative polymerase chain reactions (RT-qPCR). Conventionally, ACTB and GAPDH have been used as reference genes despite evidence from literature discouraging their use. Hence, in the present study we identified and investigated novel reference genes in SK-BR-3, an HER2-enriched breast cancer cell line. Transcriptomic data of 82 HER2-E breast cancer samples from TCGA database were analyzed to identify twelve novel genes with stable expression. Additionally, thirteen RGs from the literature were analyzed. The expression variations of the candidate genes were studied over five successive passages (p) in two parallel cultures S1 and S2 and in acute and chronic hypoxia using various algorithms. Finally, the most stable RGs were selected and validated for normalization of the expression of three genes of interest (GOIs) in normoxia and hypoxia. Our results indicate that HSP90AB1, DAD1, PFN1 and PUM1 can be used in any combination of three (triplets) for optimizing intra- and inter-assay gene expression differences in the SK-BR-3 cell line. Additionally, we discourage the use of conventional RGs (ACTB, GAPDH, RPL13A, RNA18S and RNA28S) as internal controls for RT-qPCR in SK-BR-3 cell line.
The Geo-Hydro-Mechanical Properties of a Turbiditic Formation as Internal Factors of Slope Failure Processes
Authors: Losacco Nunzio , Bottiglieri Osvaldo , Santaloia Francesca , Vitone Claudia , Cotecchia Federica
Published: October 2021

Similar to many inner areas of Southern Europe, the Daunia Apennines are affected by widespread landsliding, often consisting of slow, deep-seated movements. Recurrent acceleration of these landslides causes damage to buildings and infrastructures, severely biasing the socio-economic development of the region. Most landslides in the area of study occur within clayey units of turbiditic flysch formations, often severely disturbed by tectonic thrust and previous landsliding. The Faeto Flysch (FAE) is one of the most widespread turbiditic formations in the Daunia Apennines and is representative of the tectonised geological formations involved in slope failure. This work, by examining the landslide processes occurring at four pilot sites, aims at connecting the observed mechanisms to the geo-hydro-mechanical setup of FAE in the slopes. It is found that the soil portion of FAE consists of highly plastic clays, resulting in low intrinsic shear strength, and hence controls the initiation and progression of failure in the slopes, as such representing an internal predisposing factor to landsliding. In addition, the presence of fractured rock strata confers a high permeability at the slope scale, with respect to that of the soil matrix. This results in severe piezometric levels in the slope, which represent another internal predisposing factor to failure, and in the ability to induce significant seasonal pore water pressure oscillations down to great depths, connected to rainfall infiltration, thus triggering the recurrent acceleration of the landslides.
Performing the Bounds of Responsibility
Authors: Berger Karen
Published: October 2021

This paper investigates border-making dynamics in the two political arenas where my subjectivity is most acutely implicated across time—the Jewish Holocaust (as an intergenerational victim) and the Aboriginal genocide (as an unwitting beneficiary). Albeit that there are many differences between the drivers of antisemitism and racism against Indigenous Australians, I investigate both of these racist structures through the lens of border-thinking as theorised by Walter Mignolo as a method of decolonisation (2006). The article has been formatted as an example of discursive border-crossing by juxtaposing theoretical ideas (particularly inspired by Zygmunt Bauman and Deborah Bird Rose) with interjections from my personal journal. I explore my own performative storytelling as a means for me to take responsibility to question power structures, acknowledge injustice, and to enact the potential for ethical dialogue between myself and others. This responsibility gestures to the possibility of border crossing as an ‘act of liberation’ that resides in the acknowledgement of historical injustices and their continued impact on both the beneficiaries and the victims of coloniality in the present.
Risk Factors and Outcomes of Heart Failure Following First-Episode of Acute Myocardial Infarction—A Case Series Study of 161,384 Cases
Authors: Wang Wen-Hwa , Mar Guang-Yuan , Wei Kai-Che , Cheng Chin-Chang , Huang Wei-Chun
Published: October 2021

Background: Heart failure (HF) is one of the important complications of acute myocardial infarction (AMI), but the epidemiology, associated risks and outcomes have not been well investigated in the era of broad use of fluoroscopy-guided angiographic intervention. Methods: We analysed 161,384 subjects who had experienced the first episode of AMI during 1 January 2000 and 31 December 2012 using the Taiwan National Health Insurance Research Database. Results: During the index AMI hospitalization, 23.6% of cases developed HF. Female, ≥65 years-old, non-ST-segment elevation type of MI, diabetes mellitus (DM), peripheral vascular occlusion disease (PAOD), chronic obstructive pulmonary disease (COPD), atrial fibrillation, and ventricular tachycardia/fibrillation (VT/VF) were associated with higher risks of developing HF. HF cases had inferior survival outcomes compared to non-HF cases in both the short and long term. Among those HF patients, ≥65 years, DM, PAOD, and VT/VF were associated with worse outcomes. On the contrary, coronary reperfusion intervention and treat-to-target pharmacologic treatment were associated with favourable survival outcomes. Conclusions: HF remains common in the modern age and poses negative impacts in survival of AMI patients. It highlights that prudent prevention and early treatment of HF during AMI hospitalization is an important medical issue.
Teaching Geoheritage Values: Implementation and Thematic Analysis Evaluation of a Synchronous Online Educational Approach
Authors: Georgousis Efthymios , Savelidi Maria , Savelides Socrates , Holokolos Maximos-Vasileios , Drinia Hara
Published: October 2021

The purpose of this article is to present the results of an environmental education program on “Storm-Tossed Sea Rocks in Pelion Seaside” designed for junior high school students and implemented as a synchronous online educational approach and with a main goal to empower students to the values of geoheritage. In order to examine the effectiveness of the program and in particular the achievement of the objectives that encourage the development of values, the research question was identified as to whether the implementation of the environmental program achieved the empowerment of students in geoheritage values. In order to answer this question, we implemented a rather unusual technique to evaluate the educational procedure, which was based on the qualitative research technique of thematic analysis. This technique was selected as the most appropriate in order to “mine” conceptual patterns, the analysis of which would, in a valid, reliable, and simultaneously easy to use and quick way, inform the teachers that the values of geoheritage were disseminated to the students through the program. Thus, four-question interviews were conducted with randomly selected students who participated in the program. The data were examined and conceptual patterns were identified which were classified in eighteen codes. The codes were divided into five categories, the analysis of which led to the answer to the research question. Thus, it was found that the implementation of the environmental program achieved the empowerment of students in geocultural heritage values. The development of feelings of environmental sensitivity has also been seen, which suggests further investigation is needed. It was concluded that for the students, the given educational approach was necessary as well as cognitively, pedagogically, and emotionally beneficial; therefore, the need to enrich the curricula of environmental education/education for sustainable development with issues of geodiversity and geocultural heritage is justified. Finally, what was ascertained is that the thematic-analysis-based evaluation technique of the educational procedure, which was implemented, provided the teachers with the requested information, and it is recommended as an evaluation technique of educational procedures which aim at empowering students on values—even for daily use in school.
Original Varnish Recipes in Post-Byzantine Painting Manuals
Authors: Mastrotheodoros Georgios P. , Beltsios Konstantinos G.
Published: October 2021

During the last decades, manuscripts have become increasingly available through digitization and deposition in online repositories. This trend has very much facilitated primary source research, as scholars are no longer subjected to time- and effort-consuming processes such as travel, applications for photography permissions, and so on. In this framework, the authors set forth the results of research that deals with post-Byzantine panel-painting varnish recipes which were found in a hitherto unpublished Greek painting manual dating back to 1824. The recipes in consideration are compared to those existing in the renowned “Hermeneia” by Dionysios of Fourna (early 18th century) painter’s manual. A brief discussion dealing with various pertinent terms, along with a note on data deriving from the analytical investigation of varnish samples stemming from post-Byzantine icons are also included in this work. The study reveals a shift towards lean and intermediate varnish recipes during the early 19th century that might reflect the progression of resins and oleoresins, and the gradual replacement of oil-based varnishes. In addition, a unique recipe describing various methods of varnish application is transcribed and commented upon. Finally, the analytical data revealed an unexpected employment of a protein-based varnish in a mid-19th century icon.
Emerging Role of Neuropilin-1 and Angiotensin-Converting Enzyme-2 in Renal Carcinoma-Associated COVID-19 Pathogenesis
Authors: Hossain Md. Golzar , Akter Sharmin , Uddin Md Jamal
Published: October 2021

Neuropilin-1 (NRP1) is a recently identified glycoprotein that is an important host factor for SARS-CoV-2 infection. On the other hand, angiotensin-converting enzyme-2 (ACE2) acts as a receptor for SARS-CoV-2. Additionally, both NRP1 and ACE2 express in the kidney and are associated with various renal diseases, including renal carcinoma. Therefore, the expression profiles of NRP1 and ACE2 in kidney renal clear cell carcinoma (KIRC) and kidney renal papillary cell carcinoma (KIRP) patients from the various cancer databases were investigated along with their impact on patients’ survivability. In addition, coexpression analysis of genes involved in COVID-19, KIRC, and KIRP concerning NRP1 and ACE2 was performed. The results demonstrated that both t NRP1 and ACE2 expressions are upregulated in KIRC and KIRP compared to healthy conditions and are significantly correlated with the survivability rate of KIRC patients. A total of 128 COVID-19-associated genes are coexpressed, which are positively associated with NRP1 and ACE2 both in KIRC and KIRP. Therefore, it might be suggested that, along with the ACE2, high expression of the newly identified host factor NRP1 in renal carcinomas may play a vital role in the increased risk of SARS-CoV-2 infection and survivability of COVID-19 patients suffering from kidney cancers. The findings of this investigation will be helpful for further molecular studies and prevention and/or treatment strategies for COVID-19 patients associated with renal carcinomas.
Socioeconomic Determinants of Health and Their Unequal Distribution in Poland
Authors: Rój Justyna , Jankowiak Maciej
Published: October 2021

The purpose of this study is to identify inequities in the distribution of socioeconomic determinants of health within Poland and their impact on the health status of Poles, as measured by mortality rate. We hypothesised that (1) there are inequities in the socioeconomic characteristics within geographically defined population groups and (2) some socioeconomic determinants of health have a particularly strong impact on the health status of Poles. Poland is administratively divided into three levels: voivodeships, powiats and gminas. We used a dataset covering all 380 powiats in Poland for the year 2018. We employed a two-stage nested Theil index and Herfindahl–Hirschman Index. In order to identify which of these determinants has the strongest impact on health, we conducted a regression analysis. The study revealed some inequities in the distribution of socioeconomic determinants of health. The mortality rate can be partly understood from variations within voivodeships in the distribution of health determinants. Important national inequalities were found in the case of two determinants, which simultaneously proved their significant impact on Poles’ health in the regression analysis. Thus, type of employment and access to modern infrastructure should be of particular concern for public authorities.
A Bibliometric and Visual Analysis of Global Community Resilience Research
Authors: Yang Qiaoyun , Yang Dan , Li Peng , Liang Shilu , Zhang Zhenghu
Published: October 2021

Resilience is an important issue in urban development, and community resilience (CR) is the most typical representative in building urban resilience, which has become the forefront of international resilience research. This paper presents a bibliometric and visual analysis of community resilience research collected from the WoS Core Collection database over the past two decades. H-index, citation frequency, centrality and starting year were adopted to analyze the research objects by bibliometric tools including CiteSpace, VOSviewer, and Gephi. The national and institutional characteristics of macro-geographical distribution and the characteristics of disciplines, journals, authors, and author cooperation of micro-knowledge network distribution were revealed. Finally, the potential research directions of community resilience in the future were discussed. The results show that there are three stages in community resilience research. Seven intellectual bases constitute the research background for community resilience, including social capital mechanism, the evolution of resilience knowledge, earthquake resistance and disaster mitigation, substance abuse, resilient development in rural communities, resilience-building in the least-developed countries, and emergency preparedness. Our analysis shows that the hottest community resilience research topics are the concept of resilience, climate resilience, the social capital mechanism, macro-environment and disaster-reduction policies, and an evaluation index system for community resilience.
The Effect of Rapport on Data Quality in Face-to-Face Interviews: Beneficial or Detrimental?
Authors: Horsfall Melany , Eikelenboom Merijn , Draisma Stasja , Smit Johannes H.
Published: October 2021

The benefits of rapport between interviewers and respondents, in terms of recruiting the latter and motiving them to participate in research, have been generally endorsed. However, there has been less clarity with regard to the association between rapport and data quality. In theory, rapport could be beneficial if it motivates people to give complete and honest responses. On the other hand, efforts to maintain rapport by exhibiting pleasing and socially desirable behaviour could well be detrimental to data quality. In a large longitudinal epidemiological sample, generalized estimating equations (GEE) analyses were used to examine the association between rapport and the following three quality indicators: missing responses, responses to sensitive questions, and consistency of responses. The results of these analyses indicate an association between a high level of rapport and fewer missing responses. In contrast, we found more socially desirable responses for the high-rapport group. Finally, the high-rapport group did not differ from the low-rapport group in terms of the consistency of their responses.
Feasibility and Effectiveness of Recruiting Latinos in Decídetexto—A Smoking Cessation Clinical Trial from an Emergency Department Patient Registry
Authors: Arana-Chicas Evelyn , Cartujano-Barrera Francisco , Ogedegbe Chinwe , Ellerbeck Edward F. , Cox Lisa Sanderson , Graves Kristi D. , Diaz Francisco J. , Catley Delwyn , Cupertino Ana Paula
Published: October 2021

There is an underrepresentation of Latinos in smoking cessation clinical trials. This study describes the feasibility and effectiveness of recruiting Latino smokers in the U.S. from an emergency department (ED) patient registry into a randomized smoking cessation clinical trial. Recruitment occurred from the Hackensack University Medical Center ED. Potential participants were contacted from a patient registry. The primary outcome was whether the participant responded to a call or text. Secondary outcomes included the best day of the week, week of the month, and time of day to obtain a response. Of the 1680 potential participants, 1132 were called (67.5%), while 548 (32.5%) were texted. For calls, response rate was higher compared to text (26.4% vs 6.4%; p < 0.001). More participants were interested in the study when contacted by calls compared to text (11.4% vs. 1.8%) and more participants were enrolled in the study when contacted by calls compared to text (1.1% vs. 0.2%). Regression models showed that ethnicity, age, time of day, and week of the month were not significantly associated with response rates. Recruitment of Latinos from an ED patient registry into a smoking cessation clinical trial is feasible using call and text, although enrollment may be low.
Counseling in Vape Shops: A Survey of Vape Shop Managers in Switzerland
Authors: Joss Sandra , Moser Anna , Jakob Julian , Tal Kali , Etter Jean-François , Selby Kevin , Schoeni Anna , Poirson Philippe , Auer Reto
Published: October 2021

Vaporizers (e-cigarettes) are the most common smoking cessation aids in Switzerland, but we do not know what information customers receive in vape shops. We surveyed vape-shop managers to find out what recommendations they make to their customers. An interdisciplinary group developed the questionnaire. Respondents self-reported their smoking history, demographics, and the recommendations they thought they would give to hypothetical customers in clinical vignettes. We also queried if they collaborated with health care professionals. Of those contacted, 53.8% (70/130) of vape-shop managers responded, and 52.3% (68/130) were included in the final analysis. Managers were mostly male and ex-smokers who switched to vaporizers; 60.3% would encourage a hypothetical smoker with high nicotine dependence to start with the highest possible nicotine concentration when switching to vaporizers. For this smoker, 36.9% would recommend high (≥15 mg/mL), 32.3% medium (6–14 mg/mL), and 3.1% low (1–5 mg/mL) nicotine concentrations. The rest adapted their recommendations to fit the customer or device; 76.5% reported that physicians referred customers to them, and 78.8% would attend a course given by experts in the field of vaporizers and smoking cessation. Vape-shop managers varied widely in the recommendations they gave customers. Most reported ongoing collaboration with health care professionals and were interested in improving their counselling skills through training.
Ethical Leadership and Followers’ Emotional Exhaustion: Exploring the Roles of Three Types of Emotional Labor toward Leaders in South Korea
Authors: Lee Hyewon , An Saemi , Lim Ga Young , Sohn Young Woo
Published: October 2021

Employees’ emotional exhaustion caused by their leaders has significant consequences for both individuals and organizations. Identifying the roles of intra-organizational emotional labor is important to prevent employees’ emotional exhaustion. This study examined the relationships between ethical leadership, followers’ emotional labor toward leaders, and emotional exhaustion using Hobfoll’s conservation of resources theory. Data collected from 259 employees working in South Korea were analyzed using regression and SEM. The results indicate that ethical leadership was negatively related to followers’ emotional exhaustion. It is demonstrated that ethical leadership has a significant indirect relationship with followers’ emotional exhaustion through three types of emotional labor strategies; genuine display, faked display, and suppressed display. Through genuine display and suppressed display, ethical leadership had an indirect and negative relationship with followers’ emotional exhaustion, whereas ethical leadership and followers’ emotional exhaustion showed a positive indirect relationship through faked display. We discuss the implications and limitations of this research and future research directions.
Effects of Anthropogenic Emissions from Different Sectors on PM2.5 Concentrations in Chinese Cities
Authors: Yang Jie , Liu Pengfei , Song Hongquan , Miao Changhong , Wang Feng , Xing Yu , Wang Wenjie , Liu Xinyu , Zhao Mengxin
Published: October 2021

PM2.5 pollution has gradually attracted people’s attention due to its important negative impact on public health in recent years. The influence of anthropogenic emission factors on PM2.5 concentrations is more complicated, but their relative individual impact on different emission sectors remains unclear. With the aid of the geographic detector model (GeoDetector), this study evaluated the impacts of anthropogenic emissions from different sectors on the PM2.5 concentrations of major cities in China. The results indicated that the influence of anthropogenic emissions factors with different emission sectors on PM2.5 concentrations exhibited significant changes at different spatial and temporal scales. Residential emissions were the dominant driver at the national annual scale, and the NOX of residential emissions explained 20% (q = 0.2) of the PM2.5 concentrations. In addition, residential emissions played the leading role at the regional annual scale and during most of the seasons in northern China, and ammonia emissions from residents were the dominant factor. Traffic emissions play a leading role in the four seasons for MUYR and EC in southern China, MYR and NC in northern China, and on a national scale. Compared with primary particulate matter, secondary anthropogenic precursors have a more important effect on PM2.5 concentrations at the national or regional annual scale. The results can help to strengthen our understanding of PM2.5 pollution, improve PM2.5 forecasting models, and formulate more precise government control policy.
Dosimetric Comparison of Exposure Pathways to Human Organs and Tissues in Radon Therapy
Authors: Hofmann Werner , Lettner Herbert , Hubmer Alexander
Published: October 2021

Three therapeutic applications are presently prescribed in the radon spas in Gastein, Austria: exposure to radon in a thermal bath, exposure to radon vapor in an exposure chamber (vapor bath), and exposure to radon in the thermal gallery, a former mine. The radiological exposure pathways to human organs and tissues in these therapeutic radon applications are inhalation of radon and radon progeny via the lungs, radon transfer from water or air through the skin, and radon-progeny deposition on the skin in water or air. The objectives of the present study were to calculate radon and radon-progeny doses for selected organs and tissues for the different exposure pathways and therapeutic applications. Doses incurred in red bone marrow, liver, kidneys, and Langerhans cells in the skin may be correlated with potential therapeutic benefits, while doses to the lungs and the basal cells of the skin indicate potential carcinogenic effects. The highest organ doses among the three therapeutic applications were produced in the thermal gallery by radon progeny via inhalation, with lung doses of 5.0 mSv, and attachment to the skin, with skin doses of 4.4 mSv, while the radon contribution was less significant. For comparison, the primary exposure pathways in the thermal bath are the radon uptake through the skin, with lung doses of 334 μSv, and the radon-progeny attachment to the skin, with skin doses of 216 μSv, while the inhalation route can safely be neglected.
Environmental Risk Factors and Their Different Effects in Depressive Symptoms of Left-Behind Children in Rural China Compared with Non-Left-Behind Children
Authors: Zhang Xiaoqing , Ray Sharon A. , Hou Wei , Liu Xia
Published: October 2021

In China, 61 million children were left behind in rural areas as a result of massive urbanization and migration of parents from the countryside to the cities in search of economic opportunities. This study explores the effects of environmental risk factors (i.e., peer victimization, perceived discrimination, and stressful life events) on depressive symptoms of left-behind children (LBC) and examines whether these risk factors have a higher impact on LBC compared with that of non-left-behind children (NLBC). Data collected involve 1548 first and second-year middle school students. Logistic regressions were conducted to examine the associations between environmental risk factors and LBC’s depressive symptoms, the moderating effect of the parental separation duration on these associations, and to compare if the risk factors had a higher impact on LBC’s depressive symptoms than on those of NLBC. Peer victimization is associated with an increased likelihood of depressive symptoms for LBC who were left behind for more than five years. Finally, stressful life events have a higher impact on LBC’s depressive symptoms, while peer victimization has a higher impact on NLBC’s depressive symptoms. The results suggest that stressful life events are an important risk factor that puts LBC at a disadvantage in terms of their mental health.
Challenges for Workplace Risk Assessment in Home Offices—Results from a Qualitative Descriptive Study on Working Life during the First Wave of the COVID-19 Pandemic in Latvia
Authors: Matisāne Linda , Paegle Linda , Akūlova Lāsma , Vanadziņš Ivars
Published: October 2021

Epidemiological restrictions due to the COVID-19 pandemic have raised legal and practical questions related to the provision of workplace risk assessment in home offices of teleworkers. The objective of this qualitative study was to analyze practical experience of employers and occupational safety and health experts performing workplace risk assessment in Latvia during the first wave of the COVID-19 pandemic. Our findings suggest that employers have not sufficiently implemented their legal obligations related to workplace risk assessment which can result in an increased number of physical and mental health problems of teleworkers in the short term and in the future. Work from home has shown how different working conditions can be for the same type of work (office work); therefore, the promotion of personalized workplace risk assessment should be encouraged. Even if virtual workplace visits using photos and videos are not the traditional way the workplace risk assessment should be done, it is effective; workers who report that their employers assessed their working conditions report fewer health effects. The experience of workers in participation in workplace risk assessment for telework might change the level and role of worker participation in the management of health and safety hazards at work in general.
Menthol Smoking and Nicotine Dependence among Black/African American Women Smokers Living in Low-Resource, Rural Communities
Authors: Jones Dina M. , Kulik Margarete C. , Baezconde-Garbanati Lourdes , Bullock Sandilyn , Guy Mignonne C. , Fagan Pebbles
Published: October 2021

Black/African American women from low-resource, rural communities bear a disproportionate burden of tobacco-related morbidity and mortality. This study examined associations between menthol smoking and socioeconomic deprivation with nicotine dependence and quitting behaviors among Black/African American women cigarette and/or little cigar/cigarillo smokers, aged 18–50 living in low-resource, rural communities. Baseline survey data from a randomized controlled behavioral/intervention trial (#NCT03476837) were analyzed (n = 146). Outcomes included time to first tobacco product (cigarette/little cigar/cigarillo) use within 5 min of waking, Fagerstrom Test for Nicotine Dependence (FTND) score, and ever attempting to quit cigarettes. Socioeconomic deprivation measures included education, income, and receiving supplemental nutritional assistance (SNAP) program benefits. In adjusted regression analyses, menthol smoking was associated with both greater FTND scores and time to first tobacco product use within 5 min of waking, but not ever attempting to quit cigarettes. Regardless of menthol status, only 25.0% of smokers reported that they would quit smoking if menthol cigarettes were banned. The proportion of smokers who smoked their first tobacco product within 5 min of waking increased slightly with greater socioeconomic deprivation. Additional research and targeted efforts are needed to reduce nicotine dependence among Black/African American women smokers living in rural, low-resource communities where access to cessation services is limited.
Examining Menthol Preference as a Correlate of Change in Cigarette Smoking Behavior over a One-Year Period
Authors: Davis Danielle R. , Parker Maria A. , Delnevo Cristine D. , Villanti Andrea C.
Published: October 2021

Menthol cigarette use has been shown to be a contributing factor in the changes in smoking over time among youth. The current study aim was to use prospective survey data to identify if menthol cigarette use was associated with changes in smoking among adults. A representative cohort from the 2010 U.S. Tobacco Use Supplement to the Current Population Survey was interviewed at two time points one year apart. Respondents were past-30-day cigarette smokers at Wave 1 or Wave 2 categorized by menthol vs. non-menthol flavor preference (n = 3668). Trajectories were categorized as maintained, increased, or decreased smoking behavior between Waves. Multinomial logistic regressions examined if menthol cigarette use was associated with an increase/decrease in smoking behavior, adjusting for age, race/ethnicity, and sex. Menthol cigarette use was not associated with change over time in cigarette smoking in adult smokers. Age, race/ethnicity and sex were associated with changes in cigarette smoking. Young (vs. older) adults were more likely to increase smoking. Black and Hispanic smokers (vs. white smokers) were more likely to report any change in smoking. Males were less likely than females to change smoking behavior. Menthol status was not associated with changes in smoking among adults; however, young age, race/ethnicity, and sex were, suggesting populations to target for intervention.
Mapping Institutional Interventions to Mitigate Suicides: A Study of Causes and Prevention
Authors: Ullah Zia , Shah Nighat Akbar , Khan Sonia Shamroz , Ahmad Naveed , Scholz Miklas
Published: October 2021

Suicide is an extreme, tragic act and an important subject for social inquiry. It is the rising public health issue prevalent in the Himalayan range of Pakistan. The young and educated population is more prone to suicide instead of using this prime phase of age productively. Unfortunately, the suicide problem remains unaddressed, the causes remain undefined, solutions are not in the works, and in situations when others play a part in driving someone to commit suicide, no one is being held accountable. This study is aimed at uncovering the root causes of suicide and proposing some preventive measures to mitigate the problem. Our team studied three years’ worth of data (2017–2019) on suicides from the office of Human Rights Commission of Pakistan, Chitral. In addition, we conducted semi-structured interviews of different stakeholders, including family members, neighbors, lawyers, and police personnel. The findings revealed that extended family pressures, the power dynamic between sustainers and dependents, family conflicts, and inheritance cases were the major causes of the domestic violence that preceded suicide attempts. Mental health issues, forced marriages, academic competitions, and flawed litigation processes were also among the leading causes of suicide. Awareness through education and religious sermons, strengthening healthcare organizations, restructuring family systems, establishing police complaint centers, effective prosecution processes, and imparting lifesaving skills have been identified as measures to prevent suicide. This study has theoretical and practical implications, as it adds certain novel variables regarding the causes and solutions of suicide to the existing body of literature and guides public authorities to strengthen institutions to intervene effectively.
Visualizing the Invisible: Visual-Based Design and Efficacy in Air Quality Messaging
Authors: Rosen Zoey , Bice Channing , Scott Stephanie
Published: October 2021

This study examines the effect and efficacy of visual designs for messages about poor air quality. The study utilized a 2 (message efficacy: high vs. low) × 2 (message design: visual vs. text) between-subjects experimental design, of N = 95 students from a large Western university. This experiment assessed the effects of message design and efficacy of language on students’ visual comprehension, source credibility, self-efficacy, and protective behavioral intention. Hypotheses 1 and 2 were partially supported, finding that there were some statistically significant effects for efficacy and message design on students’ comprehension and protective behavioral intention. Future work should focus on strategies for more salient air quality health communication because wildfires will continue to impact the western United States.
School-Level Economic Disparities in Police-Reported Crimes and Active Commuting to School
Authors: Burford Katie , Ganzar Leigh Ann , Lanza Kevin , Kohl Harold W. , Hoelscher Deanna M.
Published: October 2021

Perceived safety remains one of the main barriers for children to participate in active commuting to school (ACS). This ecological study examined the associations between the number of police-reported crimes in school neighborhoods and ACS. The percentage of active travel trips was assessed from a teacher tally survey collected from students across 63 elementary schools that were primarily classified as high-poverty (n = 27). Geographic Information System (GIS) was used to create a detailed measure of police-reported crimes during 2018 and neighborhood covariates that occurred within a one-mile Euclidean buffer of the schools. Statistical analyses included linear fixed effects regressions and negative binomial regressions. In fully-adjusted models, reported crime did not exhibit significant associations with ACS. Medium-poverty schools were indirectly associated with ACS when compared to high- and low-poverty schools in all models (p < 0.05). Connectivity and vehicle ownership were also directly associated with ACS (p < 0.05). Low- and medium-poverty schools were indirectly associated with all types of reported crime when compared to high-poverty schools (p < 0.05). Although reported crime was not associated with school-level ACS, differences in ACS and reported crime do exist across school poverty levels, suggesting a need to develop and promote safe and equitable ACS interventions.
The Route of Stress in Parents of Young Children with and without Autism: A Path-Analysis Study
Authors: Leonardi Elisa , Cerasa Antonio , Servidio Rocco , Costabile Angela , Famà Francesca Isabella , Carrozza Cristina , Spadaro Letteria , Scifo Renato , Baieli Sabrina , Aiello Stefania , Marino Flavia , Tartarisco Gennaro , Vagni David , Pioggia Giovanni , Ruta Liliana
Published: October 2021

We provide a conceptual model on the complex interaction between stress, psychological predisposition, and personality traits, accounting for gender, in parents of children with and without autism. We performed a path analysis using a structural equation modeling approach in a sample of parents including 60 ASD and 53 TD couples. In parents of typically developing children (TD), depression level and age are the main direct predictors of stress through the mediating effect of anxiety. Otherwise, in the ASD parent group, the personality trait ‘openness’ directly predicts the defensive response and stress levels without the mediating effect of anxiety. Our data suggest a route of action in promoting new behavioral strategies to prevent parenting stress, making families run smoothly.
Efficacy of Communication Techniques and Health Outcomes of Bushfire Smoke Exposure: A Scoping Review
Authors: Heaney Emily , Hunter Laura , Clulow Angus , Bowles Devin , Vardoulakis Sotiris
Published: October 2021

Public health officials communicate the relevant risks of bushfire smoke exposure and associated health protection measures to affected populations. Increasing global bushfire incidence in the context of climate change motivated this scoping review. English-language publications related to adverse health outcomes following bushfire smoke exposure and publications relating to communication during natural disasters were included. Bushfire smoke events potentially increase healthcare contact, especially presentations triggered by respiratory illness. At-risk populations include those with underlying cardiorespiratory disease, elderly, paediatric, pregnant persons, and First Nations people. We found that social media, television, and radio are among the most common information sources utilised in bushfire smoke events. Message style, content, and method of delivery can directly influence message uptake and behaviour modification. Age, rurality, and geographical location influence information source preferences. Culturally and linguistically diverse groups and those with hearing, vision, and mobility-related disabilities may benefit from targeted health recommendations. This review emphasises the health effects of bushfire smoke exposure and related communication recommendations during and after bushfire smoke events. Additional investigation may further clarify the health effects of bushfire smoke exposure and efficacy of related health messaging, particularly in at-risk populations. Quantitative comparison of communication methods may yield more specific recommendations for future bushfire smoke events.
Generalized Anxiety as a Risk Factor for Dysfunctional Eating Behavior after Obesity Surgery during the COVID-19 Pandemic
Authors: Pfeiffer Corinna , Schweda Adam , Schüren Lynik Chantal , Niedergethmann Marco , Steinbach Jasmin , Rentrop Vanessa , Robitzsch Anita , Dörrie Nora , Bäuerle Alexander , Teufel Martin , Skoda Eva-Maria , Weismüller Benjamin
Published: October 2021

Purpose: The present study investigates the impact of obesity surgery on mental health (i.e., eating behavior and distress) during the COVID-19 pandemic. Methods: Two hundred fifty-four participants were recruited via social media. One hundred fourteen (44.53%) of them were surgery candidates (waiting for obesity surgery), while 142 (55.46%) had already undergone surgery. Participants who underwent surgery were compared to participants that did not yet undergo surgery in terms of mental burden (depression and anxiety), as well as safety and eating behavior. Further moderation analyses attempted to identify risk factors for increased COVID-19-related dysfunctional eating behavior after surgery. Results: Participants who underwent surgery showed generally lower levels of depression and general anxiety on a trend level. Moderation analyses suggested that people with high levels of generalized anxiety actually show more dysfunctional COVID-19-specific eating behavior after obesity surgery. Conclusion: On a trend level, obesity surgery appears to attenuate symptoms of generalized anxiety and depression. Yet, surgery patients with high levels of generalized anxiety exhibit even higher levels of dysfunctional eating during the COVID-19 pandemic. It is therefore particularly important to support people at risk.