bluuebunny/crossref_metadata_2025 huggingface dataset:
CURRÍCULO E UTOPIAS EM MEIO AO NEGACIONISMO
Authors: Chizzotti Antonio , Almeida Maria Elizabeth Bianconcini de
Published: April 2021

Em tempos conturbados pela gravidade de uma pandemia avassaladora e pela proliferação de receituários improvisados, a avaliação científica de fenômeno de tal gravidade, como a Covid-19, constrange pesquisadores, atônitos com as providências intemperantes de agentes políticos, diante de um negacionismo – a deliberada negação de uma realidade patente, empiricamente identificável, utilizada como forma de escapar de uma verdade desconfortável. A análise desse acontecimento tem o condão de revelar os desacertos teóricos dos discursos negacionistas e as graves consequências práticas para a vida humana.A avaliação tornou-se uma prática rotineira na atividade acadêmica e consolidou-se como um meio de controle do discurso e da produção científica, afastando argumentos inconsistentes e práticas inconsequentes. Foi estendida à produção científica dos pesquisadores e tornou-se um mecanismo de regulação da vida acadêmica e um instrumento de governo da conduta ética em ciência.Nesse momento grave para a sanidade do País, assolado por assombrosa mortandade, a avaliação da pandemia não pode tolerar o bizarro discurso negacionista do poder público e obriga todos os cientistas, com longo tirocínio nos processos avaliativos, a exigir das autoridades públicas um discurso distante de fabulações fantasiosas e uma prática que, cientificamente, garanta a vida dos cidadãos.A edição deste volume, especialmente deste número, traz o esforço de muitos pesquisadores, empenhados em contribuir com a elevação ética e social do Brasil no campo da educação.Nessas condições dramáticas da vida, a Revista e-Curriculum mantém sua periodicidade, e esta edição 19, número 1, de janeiro/março de 2021 contempla vinte e quatro artigos, todos advindos da crescente demanda espontânea, respeitando a distribuição pelas diferentes regiões do Brasil, além de abarcar dois artigos de outros países de língua portuguesa. Os artigos estão organizados em torno das temáticas: currículo, cultura e políticas curriculares em diferentes áreas de formação e níveis de ensino; formação de professores alfabetizadores; educação infantil; pedagogia da alternância; pedagogia freireana; tecnologias em educação e seus desdobramentos; educação do campo/rural.
SCRATCH: POSSIBILIDADES REAIS PARA PRODUÇÃO TEXTUAL EM AMBIENTE FORMAL DE APRENDIZAGEM?
Authors: Brochado Eliana Alice , Hornink Gabriel Gerber
Published: April 2021

O presente trabalho, cujo objetivo foi compreender como alunos se apropriam de Narrativas Digitais, apresenta resultados de uma investigação relacionada ao uso da linguagem de programação Scratch em aulas de Língua Portuguesa. O aporte teórico se deu com base nos princípios socioculturais de J. Wertsch e nos Novos Estudos do Letramento. Apoiamo-nos no método de estudo de caso, sendo um caso único de caráter exploratório e descritivo para produção de dados. Para tal, valemo-nos das seguintes técnicas: observação participante, com anotações em jornal de pesquisa, questionário e análise de artefatos físicos. Os sujeitos foram 26 alunos dos anos iniciais do segundo ciclo do Ensino Fundamental da Educação Básica de uma escola pública do Estado de Minas Gerais. Entre os achados, obtivemos indícios de que o Scratch pode favorecer, de maneira lúdica e usual, a produção de texto, bem como potencializar situações reais para tal trabalho.
FORMAÇÃO DE PROFESSORES ALFABETIZADORES: DESAFIOS DA DOCÊNCIA
Authors: Noffs Neide De Aquino , Wasilewski Cassiana Da Silva
Published: April 2021

Este artigo é um recorte da pesquisa Formação de Professores Alfabetizadores: Desafios da docência, realizada no programa de Pós-Graduação em Educação: Currículo da Pontifícia Universidade Católica de São Paulo, com apoio da Capes. Esta investigação teve como objetivo apresentar um perfil das professoras alfabetizadoras, em exercício, em três escolas da rede municipal de São Paulo na Diretoria Regional do Butantã (DRE-BT). Os sujeitos de pesquisa foram os regentes dos 1º e 2º anos do ensino fundamental. Utilizou-se como referência Braslavsky, Ferreiro, Noffs, Soares, entre outros. A metodologia é de enfoque qualitativo com análise documental, leitura bibliográfica específica e entrevistas. Os resultados evidenciaram as lacunas existentes na formação acadêmica inicial, a necessidade de atualização constante sobre pedagogia da infância, dos saberes docentes essenciais para a sua atuação e o conhecimento do aluno.
ACABOU A PAZ! ISTO AQUI VAI VIRAR O CHILE!: PERCURSOS PEDAGÓGICOS E RESISTÊNCIA NAS OCUPAÇÕES ESTUDANTIS
Authors: Oliveira Rafael Bastos Costa de , Breder Débora , Fonseca Mirna Juliana Santos
Published: April 2021

O objetivo deste artigo é analisar o fenômeno ocorrido no final de 2015, quando estudantes das escolas públicas da rede estadual de educação de São Paulo ocuparam cerca de 200 escolas contra a chamada “Reorganização Escolar”. Analisa-se o documentário Acabou a paz! Isto aqui vai virar o Chile! (2016), de Carlos Pronzato, procurando compreender a dimensão político-pedagógica dessa experiência coletiva, tratando da mediação entre a política de governo, das ocupações e do filme como memória. Destaca-se a escolha dos temas curriculares elencados pelos estudantes que focaram questões de resistência, feminismo e tiveram como princípio formas de organização autogestionárias, democráticas e participativas. A escuta das falas se pautou na análise de conteúdo, contando com a filosofia da práxis como referência teórico-analítica. A investigação conclui que a luta estudantil resultou em uma disputa de hegemonia acirrada, na qual a experiência política desenvolvida pelos jovens deixa legado importante e vitorioso para a luta por uma educação democrática, de qualidade e socialmente referenciada.
CURRÍCULO EM MOVIMENTO: TRAJETÓRIA E CONCEPÇÕES
Authors: Bandeira Monique Vieira Amorim , Dantas Otília Maria Alves da Nóbrega Alberto
Published: April 2021

Este estudo apresenta uma análise da proposta curricular da Secretaria de Estado de Educação do Distrito Federal, concluída e entregue aos professores e demais profissionais em 2014 e atualizada em 2018. O objetivo é refletir sobre os princípios orientadores da proposta, identificando fundamentos teóricos e metodológicos para os Anos Iniciais do Ensino Fundamental. A metodologia é qualitativa com pesquisa bibliográfica dos documentos. Destacamos a importância de se romper com a ótica habitual e conservadora de conceber o currículo como conteúdos e habilidades a serem desenvolvidos com os estudantes, numa perspectiva linear e acumulativa de conhecimentos. Nesse sentido, a organização escolar em Ciclos é apontada como alternativa, ao propor romper com a fragmentação do processo educativo, vislumbrando uma aprendizagem significativa a partir da ressignificação da rotina escolar.
TDIC NA FORMAÇÃO DE PROFESSORES EM CINGAPURA: INTENÇÕES E AÇÕES DE USO
Authors: Pasinato Nara Maria Bernardes , Motta Everson Luiz Oliveira
Published: April 2021

Esta pesquisa buscou questionar se num contexto favorável de formação, estrutura física e tecnológica adequadas, os professores integram as tecnologias em sua sala de aula ao analisar as intenções e ações dos futuros professores no uso das tecnologias. Como metodologia, adotou-se a observação participante durante seis meses nas aulas ministradas na disciplina de Pedagogical Approaches to Teaching and Learning Principles of Accounts, no National Institute of Education em Cingapura, com encontros semanais, partindo do Modelo Pedagógico Multiestratégico (MPME) que propõe o uso intenso das TDIC. Aplicou-se a Teoria Unificada de Aceitação e Uso das Tecnologias (UTAUT) desenvolvida por Venkatesh et al. (2003). Concluiu-se que há indícios de que quando os recursos tecnológicos não estão prontamente disponíveis, tendem a afastar a ideia de integrar tecnologias nas aulas. Além disso valores, crenças e concepções individuais sobre determinado tema ou assunto, podem levar o docente a não utilização as tecnologias.
Absenteísmo por motivo de doença em profissionais da saúde em um hospital público: uma revisão
Authors: Viana Andressa Cristine Buranhaem , Martins Islane Cristina
Published: April 2021

RESUMOIntrodução: Conhecer o perfil de morbidade e os aspectos que levam ao absenteísmo é de extrema relevância, pois permite o planejamento de ações para promover ambientes saudáveis, previne doenças e auxilia na identificação e tratamento oportunos. Objetivo: Realizar uma revisão integrativa da literatura a fim de compreender o perfil do absenteísmo em diversos profissionais da área da saúde em um hospital público. Materiais e métodos: Foi feita, em junho de 2020, uma busca de referência com os descritores ‘’Absenteísmo-doença” AND ‘’Pessoal de Saúde” nas bases de dados Periódicos CAPES, Google Acadêmico e PUBMED. Pelos critérios de elegibilidade, 08 estudos se adequaram aos parâmetros estipulados. Resultados: O perfil, identificado pelos estudos, com maior índice de absenteísmo foi: pessoas do sexo feminino, entre 40 e 50 anos, com nível médio de escolaridade e tempo médio de trabalho na instituição entre 3 e 6 anos. Além disso, as doenças do sistema osteomuscular e do sistema conjuntivo e os transtornos mentais e comportamentais foram os principais responsáveis pelos afastamentos. Conclusão: O absenteísmo pode ser entendido como um fenômeno multifatorial. No entanto, após o estudo, identifica-se a existência de um perfil de acometidos e de tipos de doenças com maior influência no absenteísmo dos hospitais públicos. Uma das limitações verificadas no estudo é a concentração de pesquisas em categorias profissionais específicas, em detrimentos das demais categorias.Palavras-chave: Absenteísmo-doença, Pessoal de saúde, Hospital Público. ABSTRACTIntroduction: Knowing the morbidity profile and the aspects that provokes the absenteeism is extremely relevant, as it allows the planning of actions to promote healthy environments, prevent diseases and help in the identification and timely treatment. Objective: Carrying out an integrative literature review in order to understand the profile of absenteeism in various health professionals in a public hospital. Materials and methods: It was made a reference search in June 2020, with the descriptors “Absenteeism-disease” AND “Health Personnel” in the CAPES, Google Scholar and PUBMED periodical databases. By the eligibility criteria, 08 studies were adapted to the stipulated parameters. Results: The profile identified by the studies with the highest rate of absenteeism was female people, between 40 and 50 years old, with high school level of education and average time working at the institution between 3 and 6 years. In addition, diseases of the musculoskeletal and connective systems and mental and behavioral disorders were primarily responsible for the leave. Conclusion: Absenteeism can be viewed as a multifactorial phenomenon. Nevertheless, after the study, the existence of a profile of people affected and types of diseases with greater influence on absenteeism in public hospitals is identified.Keywords: Absenteeism-disease, Health personnel, Public Hospital.
Assistência à saúde em pediatria: uma revisão integrativa sobre os cuidados paliativos
Authors: Alves Silveira Monteiro Luciana , Correia Oliveira Camila , Aguiar Marília , Milagres Araújo Claudirene , Monteiro Raimundo
Published: April 2021

Introdução: Cuidado Paliativo é uma abordagem que promove qualidade de vida tanto dos pacientes que enfrentam doenças que ameacem a continuidade da vida, quando de seus familiares, por meio de aspectos da prevenção e alívio do sofrimento, requerendo a identificação precoce, avaliação e tratamento da dor. Pode ser realizado em diversos cenários, inclusive em pediatria. Objetivo: analisar artigos científicos disseminados em periódicos on-line acerca da temática cuidados paliativos em pediatria. Método: revisão integrativa da literatura, com coleta de dados no mês de agosto de 2020, nas bases de dados LILACS, SCIELO, MEDLINE/PubMed, IBECS. Resultados: foram selecionadas 14 publicações, cujas analises textuais permitiram a construção de quatro abordagens temáticas: o significado do treinamento no campo dos cuidados paliativos; cuidados paliativos e luto; a espiritualidade e o paciente sob cuidados paliativos e cuidados paliativos e aspectos éticos. Conclusão: estudo verificou a relevância das dimensões do cuidado paliativo em pediatria durante a assistência e a necessidade do desenvolvimento de novos estudos para disseminar conhecimento sobre o tema.
PENGARUH VARIASI PANJANG PEGAS KOPLING TERHADAP PERFORMA DAN KONSUMSI BAHAN BAKAR PADA HONDA TIGER 200 CC
Authors: Adji Panji Laksono , Winangun Kuntang , Winardi Yoyok
Published: April 2021

Good acceleration and performance are influenced by the degree of flexibility of the clutch springs. The objective that underlies the implementation of this study is to determine the effect of replacing the clutch spring with different length variations. In this study, the data taken is the torque, power and fuel consumption of each type of clutch spring. In this test, two types of clutch springs were used, namely the standard clutch spring and the TDR type coupling spring which were varied in length (38.31mm), (40.93mm) with the addition of 2mm (42.93mm), (40.31mm) rings. also cutting thread 2mm (38.93mm), (36.31mm). Tests were carried out using a dynotest tool with an engine speed of 4000 rpm to 9000 rpm transmission position six. In the TDR clutch spring (42.93mm) there is an increase in torque of 7.42% with a torque yield of 16.20 Nm at 6000 rpm and an increase in power of 6.61% with a power yield of 14.5 HP at 7000 rpm. For fuel consumption TDR coupling spring at ideal rotation (low-medium), an increase of 9.68%. The decrease in fuel consumption only occurred at the top / high speed of 6.32%. For the test results pertalite ethanol fuel, there is a decrease in fuel consumption compared to pertalite fuel for all RPM variables
INTEGRASI ALGORITMA FISHER-YATES SEBAGAI PENGEMBANGAN E-LEARNING DI UNIT KEGIATAN BELAJAR MANDIRI
Authors: Arditya Karisma Nanda , Setyawan Moh Bhanu , Cobantoro Adi Fajaryanto
Published: April 2021

E-learning is currently very important and a must for educational institutions. Many e-learning application platforms are based on Learning Management System (LMS) that can be used by schools, whether they are open source, paid for or build their own applications. There are many considerations that must be faced when deciding to use an e-learning-based application (LMS) including infrastructure readiness, costs and application compatibility with the e-learning concept desired by educational institutions. The availability of features in the e-learning system is one that must be adjusted to the e- learning concept that will be selected. Each institution may be able to determine its own characteristics that can be specific and not yet fully accommodated in the e-learning application that currently exists. One of them is the feature to randomize exam questions to ensure that each student gets different questions with the same composition. This research will try to answer this problem by integrating the fisher-yates shuffel algorithm. The success of this algorithm integration will be assessed by conducting an exam simulation involving two classes and seeing how the system will randomly divide the exam questions to each student. The first assessment is the suitability of the composition of the questions and the similarity of the questions between students, the less students receive the same questions appearing on the exam questions, the better the system performance.
Diseño, análisis y evaluación de las características termofísicas de paneles aislantes para muros, realizados con botellas reutilizadas de PET, espuma de poliuretano y acabado aparente en una de sus caras
Authors:   , Valerdi Madrigal Héctor
Published: April 2021

El siguiente trabajo de investigación surge por la necesidad e inquietud de atender diferentes edificaciones que presentan problemas de sobrecalentamiento por radiación solar directa, enfriamiento nocturno y principalmente invernal. Regularmente la envolvente de algunos espacios habitables (principalmente los de escasos recursos) no son tomados en cuenta ya que son elementos que difícilmente son considerados como parte de un diseño arquitectónico. Por lo tanto, no son atendidos por el usuario, con respecto a aislamiento térmico y mucho menos se procura un acabado final que brinde identidad a la vivienda. La regulación de la temperatura interior se lleva a cabo por medio de abrir o cerrar puertas y ventanas, muchas veces los elementos verticales son de sistemas constructivos diferentes, pueden ser de block hueco, tabique rojo, tabique gris, madera o algún tipo de lámina. En la actualidad existen algunos productos que se venden como aislantes térmicos para la construcción, principalmente espuma de poliuretano, poliestireno, fibra de vidrio, lana mineral, por mencionar algunos. Por todo lo anterior, la presente tesis tiene como objeto llevar a cabo una investigación que permita diseñar, analizar y evaluar nuevos elementos térmicos de tipo panel modular aislante para muros, conformados por la combinación de diferentes materiales, como son: El polietileno tereftalato (más conocido por sus siglas en ingles PET) en forma de botellas reutilizadas que aprovecha el aire inerte contenido como aislante de costo cero. La espuma de poliuretano de alta densidad, la cual también incorpora burbujas de aire al momento de realizar la reacción de polimerización. Fachaletas de cemento/mortero/arena con diversos acabados aparentes como tabique rojo, sillar rojo y beige, piedra laja o cantera, para soportar la intemperie, con la selección de estos estilos de fachada se evita tener que pintarlos de manera regular, reduciendo el costo de mantenimiento. La intención final de estos paneles es brindar en primer lugar el beneficio de mejorar la temperatura interior y aportar un mejor confort térmico al usuario, en segundo lugar, permite generar fachadas con mayor apropiación de estilo, de manera rápida y económica. Estos paneles, aportan un valor ecológico adicional al mitigar el impacto ambiental que genera el desperdicio del PET.
Material Excess and Deadly Dwelling in E.L. Doctorow’s Homer and Langley
Authors: Schwab Anamaria
Published: April 2021

In Homer and Langley, E.L. Doctorow’s 2009 novel of New York City, the author focuses on past Manhattan, which he sees as the epitome of his own self-destructive modern and contemporary society. I would argue that Doctorow acts here mainly to denounce excessive material culture in the context of egotistic, upper-class Manhattan dwelling at the end of the nineteenth century. I would also like to show that the novelist criticizes the idea of material progress along more than a hundred years, from the end of the nineteenth century, when the plot starts, to the beginning of the twenty-first century, when the novel was written. The self-contained, isolated world in the novel is the result of our society’s propensity for excessive production and consumption. At the same time, Homer and Langley brings to mind ideas of exhaustion of the human, who agrees to be literally replaced by objects. The fact that such a phenomenon occurs already at the end of the nineteenth century suggests that there might have never been a plenary moment of being human, as we have long entertained the closest possible relationship and even synthesis with the non-human world of objects and tools.
Welcome to the Desert of the Anthropocene: Dystopian Cityscapes in (Post)Apocalyptic Science Fiction
Authors: Tüzün Hatice Övgü
Published: April 2021

Philip K. Dick’s Do Androids Dream of Electric Sheep? (1968) and Jeanette Winterson’s The Stone Gods (2007) manifest an environmentalist awareness of the increasingly destructive power of human technologies while challenging the prevalent models we employ to think about the planet as well as its human and non-human inhabitants. Both novels probe what it means to be human in a universe plagued by entropy in the era of the Anthropocene. For the purposes of this essay, I will concentrate particularly on Dick’s and Winterson’s portrayals of the dystopian city as a site of interconnections and transformations against a backdrop of encroaching entropy and impending doom. Drawing on the work of several (critical) posthumanists who are primarily interested in dissolving oppositions such as between nature/culture, biology/technology, I show how the displacement of the centrality of human agency due to the intrusive nature of advanced technology is happening in the broader context of the Anthropocene. I also argue that the dystopian cityscapes envisioned in both novels become places that allow for the possibility of new forms of subjectivity to emerge.
Transgression and Empowerment in Sarah Hall’s Short Fiction
Authors: Fernandes Ana Raquel
Published: April 2021

This essay delivers an analysis of the innovative short fiction of contemporary British writer Sarah Hall. It gives particular consideration to the first two collections of short stories published by the author, The Beautiful Indifference (2011) and Madame Zero (2017), as well as looking into the possibilities offered by her latest collection, Sudden Traveler (2019). Hall focuses attention on such varied contemporary preoccupations as identity, gender, violence and death. My goal is to discuss the way that identities are subverted or transgressed in her short stories and how the topic of identity representation intersects with other themes becoming a fundamental and empowering factor in the narrative structure. Hall’s short story collections present an interesting case study, not only because they display the writer’s quest for a unity of subject-matter, but also because they evince the strength and vitality of the short story as a genre.
Antibacterial Activity of Spruce Bark (Picea abies L.) Extract against Escherichia coli
Authors: Tanase Corneliu , Boz Irina , Oroian Silvia , Coşarcă Sanda , Toma Felicia , Mare Anca , Man Adrian
Published: April 2021

The increase of antibiotic resistant bacteria in lasts years resulted in limited options for treatment of bacterial diseases. Escherichia coli is one of the most common Gram-negative bacterial pathogen and a cause of both community and hospital acquired infections. Medicinal plants are alternative rich sources of useful antibacterial agents. The antimicrobial activities of the spruce (Picea abies L.) bark polyphenolic extracts were examined for their capacity to inhibit the growth of Escherichia coli. Spruce bark extract was obtained by conventional aqueous extraction and with ultrasounds. The minimum inhibitory concentration was determined by microdilution method. The antibacterial effect of both extracts was strong against Escherichia coli. The antimicrobial effect of polyphenolic extracts on Escherichia coli was expressed at a concentration of 15 mg/ml. Antimicrobial activity of spruce bark compounds suggest a possible use of spruce bark in pharmaceutical preparations.
Toxicity Assessment of Nephrolepis exaltata (L.) Schott, Fam. Nephrolepidaceae
Authors: Popovici Patriciu Constantin , Ancuceanu Viorel Robert , Olaru Tudorel Octavian , Stoicescu Cristina-Silvia , Dinu Mihaela
Published: April 2021

The fern Nephrolepis exaltata (L.) Schott, fam. Nephrolepidaceae, has little traditional medicinal use. In order to estimate its potential safety, in the present study we have investigated the phytotoxicity (on Triticum aestivum L.) and toxicity on brine shrimp of extracts from plants grown hydroponically. The species identity was confirmed by macroscopic and microscopic examinations on rhizomes, rachises, pinnae and runners, using bright field and fluorescent microscopy. Biological assays were performed on aqueous and ethanol solutions of the fronds. The brine shrimp lethality assay was performed on Artemia franciscana Kellog and a phytobiological bioassay on Triticum aestivum L. Lethality, root elongation and karyokinetic film modifications were evaluated, and LC50 and IC50 values were calculated. The microscopic analysis revealed the main histo-anatomic elements: polystelic structure and hypodermis (rhizome, rachis, runners), trichomes (rachis), homogenous structure, trichomes and diacytic/anisocytic stomata (leaves). The ethanol and aqueous extracts showed low cytotoxic effects on both Triticum aestivum roots and Artemia franciscana nauplii.
Changing Pattern of Heavy Metals Accumulation in and around in Ship breaking Area Over the 40 years and Its Impact on Fish Diversity in Adjacent Areas of Bangladesh
Authors: Barua Prabal , Rahman Syed Hafizur , Barua Maitri
Published: April 2021

Coastal area of Bangladesh is one of the significant ecologically productive areas and full of rich biodiversity that includes variety of species that are endemic to this region. The Shipbreaking activity has turned out to be more significant within the economic situation of the poverty-stricken Bangladesh. The study vicinity was alienated into the Shipbreaking zone and control site for proportional investigation. The study was administered to assess the changing pattern of the concentration of trace metals in soil Soil samples of the study areas and its impact on fish diversity of the ship breaking area in Bangladesh over the 40 years. From the finding of the study, it had been found that the concentration of the heavy metals found within the ship breaking area followed a pattern within the following fashion Fe>Pb>Cr>Mn>Zn>Ni>Cu>Cd>Hg. The finding of this heavy metal analysis of sediments demonstrated that there has been in an increment of two to eight times of selected heavy metals from the finding of 1980 to 2019. The study compared with the two relatively pristine or less impacted (undisturbed) areas, that served because of the reference zone. These studies also found that about 30 species of fishes became irregular or are threatened with extinction than they were 40 years ago.
Identification of corrosion products on iron artefact from Bratislava castle
Authors: Košťúr Roman , Zemanová Matilda
Published: April 2021

Corrosion layers of an iron artefact were characterized to study long-term exposition of iron in Slovakia. The iron artefact from Bratislava castle has been coated with a strong layer of corrosion products and masonry residues. Corrosion products were characterized by different methods including energy-dispersive X-ray spectroscopy (EDX), X-Ray diffraction (XRD), and µ-Raman Spectroscopy. Magnetite and goethite on the surface are confirmed typical corrosion products from long-term atmospheric exposure in environment with corrosivity category C-2 (low).
Effect of ambient parameters change on mint leaves solar drying
Authors: Noori Abdul Wasim , Royen Mohammad Jafar , Haydary Juma
Published: April 2021

This study investigates the effect of ambient conditions change on mint leaves solar drying performance and product water activity. Two drying methods, active indirect solar drying (AISD) and open sun drying (OSD) were compared while the experiments were carried out at specific dry climate conditions. During the experimental days, temperature varied from 20 to 30 °C, air relative humidity from 14 to 28.8 % and ambient pressure was around 82 kPa. The effect of air relative humidity change during the day on the rehydration of the product during the drying process was observed. After 7 h of drying, moisture content of mint leaves decreased from 85.29 % to 5.38 % in the AISD and 7.42 % in the OSD system. The 0.97 initial water activity decreased to 0.195 in AISD and 0.79 in OSD. Rehydration during the evening hours caused an increase in product water activity from 0.2 to 0.51. Changes of ambient conditions such as temperature and air relative humidity during the day can significantly affect water activity of dried product due to its rehydration and thus increase the risk of product spoilage.
Are there cities and fairs in the neolithic? Part I – from PPN to late Neolithic (Part II is refering to Copper Age)
Authors: Lazarovici Gheorghe , Lazarovici Cornelia-Magda
Published: April 2021

In this study we have resumed the problem of Neolithic settlements with a complex architecture (defense systems with ditches, palisades, towers, bastions; residential buildings; cult constructions; social constructions) which support the idea of a proto-urban organization since the PPN. We have analyzed current definitions of cities and fairs, which mainly reflect situations from classical antiquity and the Middle Ages, but they cannot be applied to prehistoric realities, which, according to interdisciplinary research, offer another perspective. We also believe that religion too has played an important part in these sites, some of them being real centers of worship.
Preparation and evaluation of an oral mucoadhesive gel containing nystatin-loaded alginate microparticles
Authors: Mohammadi Samani S. , Karimaddini S. , Sobhani Z. , Ahmadi F.
Published: April 2021

Nystatin is an antifungal agent used for prophylaxis and treatment of candidiasis, especially oral mycosis. Efficacy of nystatin conventional dosage forms is limited by the short residence time and bitter taste of the drug. This research aims at designing an optimized formulation of oral mucoadhesive gel of nystatin-loaded alginate microparticles, which can be retained in the mouth. Sodium alginate solution containing nystatin was added to the solution of calcium chloride under stirring. Microparticles containing nystatin were incorporated into the Carbopol gel. Size, loading, and release profile and mucoadhesion were investigated. The most suitable microparticles with particle size of < 250 μm were prepared with alginate concentration of 1%(w/v), calcium chloride of 1%(w/v), drug:polymer concentration 1%, and ratio of alginate solution:calcium chloride of 1:10. This formulation showed 49.1% drug loading and 98.2% encapsulation efficiency. Carbopol 934 gel provided optimal mucoadhesive properties. Release profile proved a burst release, which can be attributed to the surface associated drug, followed by a slower sustained release phase for all microparticles. The developed system with ability to adhere to the oral mucosa has great appeal for treatment of localized infections and can mask bitter taste of the drug and be retained in the mouth for long periods.
Study of the Qualitative Composition and Quantitative Content of Parthenolide in the Feverfew (Tanacetum Parthenium) Herb Cultivated in Ukraine
Authors: Hordiei K. R. , Gontova T. N. , Gubar S. N. , Yaremenko M. S. , Kotova E. E.
Published: April 2021

Feverfew is a well-known medicinal plant as a source of the sesquiterpene lactones, the main one is a parthenolide (about 85%). Owing to the parthenolide, feverfew herb has anti-inflammatory activity and it is widely used for prevention of migraine. The aim was to study the qualitative composition and quantitative content of the parthenolide in the samples of the feverfew herb cultivated in Ukraine and to study the influence of environmental factors on the accumulation of parthenolide.

Methods

The identification in the samples of the feverfew herb by the thin-layer chromatography method was carried out on silica gel 60 F254 plates, Merck. For the quantitative determination of the parthenolide, a high-performance liquid chromatography ProStar equipped with a diode-matrix detector, were used.

Results

The chromatographic profile of the samples of the feverfew herb was studied using a TLC method. In the chromatograms of test solutions from all samples, the blue zones were detected at the level of parthenolide. The quantitative content of parthenolide ranged between 0.16% and 0.39%. The highest content was observed in the sample from the Central region of Ukraine. The data obtained indicate that the optimal conditions for parthenolide accumulation in feverfew herb are as follows: black soils, solar insolation not higher than 5.25 kWh/m2/day, average air temperature from +20°C to +25°C. All the calculated validation parameters of the parthenolide quantitative determination method meet the necessary acceptance criteria.

Conclusion

The study of the qualitative composition and quantitative content of parthenolide in the samples of feverfew herb cultivated in different regions of Ukraine has been conducted. According to the methodology of Eur.Ph. and SPhU, a parthenolide was identified in all the samples. HPLC method was used to determine the quantitative content of parthenolide in the samples studied. The optimal conditions for parthenolide accumulation in feverfew herb were established.
Potential Application of Biochar Depends Mainly on Its Profits for Farmers: Case Study in Slovakia
Authors: Šimanský Vladimír , Aydın Elena , Igaz Dušan , Horák Ján
Published: April 2021

Current biochar application in the global agronomic practice focuses firstly on economic profits. In this paper, we would like to draw attention to our results and experience from the economic assessment of the agronomic effect of applied biochar through the generated crop yields. The results come from a field experiment (locality Dolná Malanta, Slovakia, silt loam Haplic Luvisol – the most intensively used soil in the Slovak Republic for agricultural purposes), where a biochar experiment was established in 2014. Based on our data, it is evident that both the application of biochar and its application in combination with N-fertilisation in field conditions at current realization prices of commodities in individual years and high input costs are still unprofitable. However, we emphasize that from an economic point of view of the stand ard agronomic practice.
Epidemiology of occupational injuries among insured workers in Saudi Arabia between 2004 and 2016
Authors: Abbas Mohsin , Saeed Rashid , Asam Zaki-ul-Zaman
Published: April 2021

This is a retrospective analysis of annual reports on occupational injuries issued by the national social insurance agency of the Kingdom of Saudi Arabia (KSA) for the years 2004 through 2016. For each criterion we calculated an index based on the equation NY/Nref
x100, where NY
is the number of occupational injuries by a specific criterion in a specific year Y, and Nref
is the number of injuries in the corresponding criterion in the reference year, i.e. 2004. We also calculated the number of injuries to number of workers ratio (Ni/Nw
) for different occupations and economic sectors to get a clearer idea of the injury trends per worker. In terms of occupational injury rates (with respect to 2004), we observed increases in construction, financing & real estate (economic sectors), among engineers and technicians (occupations), in infections and secondary contusions (injury type), for upper and lower limbs (affected body parts), over falls and “other” causes. Most injuries occurred on Fridays, which is a weekend day in Saudi Arabia. We also observed increased recovery without disability (injury status). However, if we look at the number of occupational injuries per worker, we can see a decreasing trend over time for all occupations and economic sectors, most likely thanks to improved labour law and safety at work practices for insured workers. Our findings are similar to reports from other Persian Gulf countries and reflect current labour health and safety issues in the area.
Presence of nitrosamine impurities in medicinal products
Authors: Sedlo Ilijana , Kolonić Teo , Tomić Siniša
Published: April 2021

In 2018, some sartan medicinal products were reported to be contaminated with nitrosamine compounds, which are potent mutagenic carcinogens. Two nitrosamines received particular attention: N -nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA). These have since been confirmed in different types of medicinal products, including ranitidine and metformin. Consequently, the European Medicines Agency (EMA) started an investigation into the cause of contamination and an assessment of the risk to patients taking contaminated medicinal products. The main source of contamination were changes in production, which involves combinations of amines and nitrogen compounds and the use of specific catalysts and reagents. Withdrawals of medicinal products that took place in Croatia did not lead to a shortage of sartan- or metformin-containing medicines. Moreover, ranitidine had been preventively withdrawn all over the EU, including Croatia, creating shortages at the time, but was subsequently replaced with therapeutic alternatives.
Apperception: Understanding and Anticipating the User in Space Based on Neural and Behavioural Responses
Authors: Šimkovič Vladimír , Kulifaj Ivan
Published: April 2021

The main task of architecture has been and will be to create spaces for the user. Our experiment is based on an interdisciplinary study, combining knowledge from architecture, neuroscience, psychology and artificial intelligence. We think that these disciplines can better interpret the users’ perception to architects and designers, because how do we know what users want and how they react to the created matter? This fundamental question underlines the research, designates its direction and goals. The futuristic view and exploring the user is one aspect, complemented by the application of research results to today’s reality. Nowadays, in Slovakia (and in the world), urban development is funded by the private sector and is significantly limited by the financial aspect of architecture and development, it is necessary to look for a concept that reduces the importance of finance at the expense of quality for users.
Regarding new wave distributions of the non-linear integro-partial Ito differential and fifth-order integrable equations
Authors: Baskonus Haci Mehmet , Kayan Mustafa
Published: April 2021

This paper applies a powerful scheme, namely Bernoulli sub-equation function method, to some partial differential equations with high non-linearity. Many new travelling wave solutions, such as mixed dark-bright soliton, exponential and complex domain, are reported. Under a suitable choice of the values of parameters, wave behaviours of the results obtained in the paper – in terms of 2D, 3D and contour surfaces – are observed.
A finite element analysis of the impact of split pole shoes on magnetic liquid sealing performance
Authors: Zhiguo Liu , Huitao Zhang , Li Yang
Published: April 2021

Though split pole shoe can solve the problems of increased cost and decreased efficiency caused by replacing pole shoes in the test, assembling and use of split sealing devices, it fails to overcome the issue of sealing in the gap between split pole shoe's junction surface and shaft. In this paper, a split magnetic liquid sealing structure is designed, combining magnetic liquid sealing and split pole shoe's plane sealing. In our study, we have adopted three methods for split sealing and use theory and simulation to ascertain the sealing performance of the split magnetic liquid sealing structure designed by us. The results indicate that magnetic sealant bonded split pole shoes show better sealing performance as compared to those bonded by ordinary sealant, and that the structural optimisation results can meet the requirement for sealing performance. The simulation results coincide with theoretical results, which proves the correctness of this research.
Clinical and Evolutive Features in Syphilis - HIV Coinfection
Authors: Iancu Gabriela Mariana , Todan Liliana Elena , Rotaru Maria
Published: April 2021

Syphilis is a systemic infection caused by Treponema Pallidum spirochete, which is considered to be the main sexually transmitted disease. The genital ulcerations and local inflammation found in syphilis are favouring factors involved in transmitting the HIV infection. Recent data suggests that individuals suffering from other sexually transmitted diseases are 3 to 5 times more exposed to developing HIV infection. On the other hand, simultaneous HIV infection may worsen the syphilis evolution. In the light of this data we present the case of a patient with syphilis-HIV coinfection recently diagnosed and we will summarize the clinical and evolutive features of the syphilis-HIV coinfection.
Risk Factors Regarding Portal Vein Thrombosis in Chronic Liver Disease
Authors: Vecerzan Liliana , Mihăilă Romeo Gabriel
Published: April 2021

The portal vein thrombosis (PVT) is one of the most frequent vascular diseases of the liver, with a high rate of morbidity and mortality. The most common causes of the PVT are hepatic cirrhosis, hepatobiliary neoplasms, inflammatory and infectious abdominal diseases, and myeloproliferative syndromes.(1,2) The natural progress of the PVT has as a result portal hypertension which leads to splenomegaly and the formation of portosystemic collateral vessels, as well as gastroesophageal, duodenal and jejunal varices. Ultrasonography, especially Doppler ultrasound, is the most widely used imaging method to asses, supervise and diagnose PVT in patients with hepatopathies. The purpose of acute PVT treatment is to re-permeabilize the obstructed vessels; the endoscopic ligature of the varices in the eventuality of their rupture is safe and extremely efficient in chronic PVT. To conclude, PVT is the most common hepatic vascular disorder, and its prevalence has increased particularly among the patients with chronic hepatopathies.(3)
Pediatric Atopic Dermatitis: Update on the Treatment Options
Authors: Zah Corina Adelina , Toporău Andreea Emiliana , Grama Paul
Published: April 2021

Atopic dermatitis (AD) is a chronic inflammatory disease characterized by skin dryness, pruritus and eczematous lesions with various periods of relapse. Symptomatology can appear in childhood and can persist in adulthood. Chronic treatment is required with corticosteroids being the standard options. The side effects of this type of long-term treatment represent a major concern for the pediatric patients. This review aims to give an update of the options used for treatment, apart from the systemic corticosteroids. Mild-to-moderate AD had a good response to creams containing fig and oatmeal extracts and inhibitors of phosphodiesterase-4 (crisaborole). In cases of severe AD, future treatment options could include monoclonal antibodies such as omalizumab and dupilumab
Colonization of Candida After the Placement of a Tongue Piercing, a Case Report
Authors: Ledan-Muntean Szende , Tudor Bianca
Published: April 2021

The practice of piercing the body’s different areas is a commonly observed form of body modification. It implies puncturing the skin tissue resulted in an opening, in which specific jewellery or an intradermal implant could be inserted. The tongue piercing is a highly popular form of this practice, but can be followed by multiple acute and chronic complications, such as bacterial and fungal infections. Our case describes the clinical situation of a 25 year old immunocompetent woman, who sought medical help after observing tissue abnormalities, following a newly inserted tongue piercing. We identified a correctly and professionally placed tongue jewellery associated with all clinical hallmarks of oral Candidiasis. Our aim was to microbiologically identify and treat the present yeast colonies.
The “Sitting” Position and Its Implications in Dental Technology. General Aspects of Improving the Quality of Life - Part II
Authors: Burcea Claudia-Camelia , Perieanu Mădălina Violeta , Burlibaşa Mihai , Costea Radu , Perieanu Viorel Ștefan , Tănase Gabriela , Ionescu Camelia , Babiuc Iuliana , Neagoe Ioana-Cristina , Costea Raluca , Mihai Augustin , Dina Magdalena Natalia , Maliţa Mădălina Adriana , Tănase Gabriela , Marcov Elena-Cristina , Chirilă Mihaela
Published: April 2021

Nowadays, at work, many people spend more than half of their entire day working in a sitting position. Maintaining this position for a long period of time is a risk factor for health. The results of various studies have shown associations between maintaining a prolonged sitting position with morbidity due to chronic diseases, such as cardiovascular disease, diabetes, metabolic syndrome, obesity, etc. And, as we have already mentioned in the first part of this study, dental technicians are part of this category of staff, who carry out most of their specific activity, in a sitting position.
Fennel and Ginger Improved Nutrient Digestibility and Milk Yield and Quality in Early Lactating Egyptian Buffaloes
Authors: Fahim Nadia H. , Kholif Ahmed E. , Azzaz Hossam H.
Published: April 2021

The supplementation with herbal and medicinal plants to animals showed positive effects on feed digestion, performance and animal’s health. Fifteen multiparous Egyptian buffaloes (537 ± 18.1 kg body weight), 7 days after parturition, were randomly assigned to 3 treatments in a quintupled 3 × 3 Latin square design in a 63-day experiment. Each experimental period lasted 21 days (15 days of adaptation + 7 days for measurements and samples collection). Buffaloes were assigned according to their previous milk production, weight and parity to study the effect of fennel (Foeniculum vulgare) or ginger (Zingiber officinale) supplementation on feed utilization and lactational performance. Buffaloes were fed a basal diet of concentrates, berseem clover and rice straw in a ratio of 60:30:10 dry matter (DM) basis. The first group was fed the basal diet with no additive as the control treatment, while other buffaloes were fed on the basal diet supplemented with 75 g fennel or ginger/buffalo daily. Additives supplementation did not affect feed intake; however, fennel followed by ginger improved (P<0.05) dry matter, organic matter, crude protein and neutral detergent fiber digestibilities compared to the control. Without affecting blood chemistry, fennel and ginger supplementation improved (P<0.05) production of milk and energy corrected milk, fat concentration and milk energy content and output. Fennel followed by ginger decreased the somatic cell count (P=0.035) compared with the control. Fennel and ginger improved feed efficiency (P<0.05) compared with the control. Fennel increased the proportion of milk trans-10, cis-12 C18:2 (P=0.028), total conjugated linoleic acid without affecting other fatty acids. It is concluded that fennel or ginger at 75 g/buffalo/d improved nutrient digestibility and milk production of lactating buffaloes. Fennel improved milk nutritive value more than ginger.
Assessment of pulp and paper mill effluent quality and its toxicity to fingerlings of Cyprinus carpio
Authors: Dey Sangeeta , Choudhury Manabendra Dutta , Das Suchismita
Published: April 2021

Effluents from a pulp and paper mill in India were analyzed for various physicochemical parameters and heavy metals. Multivariate statistical analysis was used to interpret the data obtained and predict the toxicity of each component to Cyprinus carpio L. fingerlings. The results showed that most of these parameters exceeded recommended levels set by various agencies, and the effluent was not suitable for discharge into agricultural fields or water bodies without further treatment. The results of static renewal toxicity tests revealed median lethal concentrations at 24, 48, 72, and 96 h to be 42, 25, 18.6 and 14.5%, respectively, and the fingerlings exhibited severe behavioral anomalies. The sublethal dose of 2.9% (v/v) caused alterations in the gill and liver at durations of 7, 14, 21, and 28 d. Anomalies such as mucous secretion, leucocyte infiltration, curling of the secondary lamellae tip, clubbing, and the fusion of the secondary lamellae, aneurism, etc. were prominent. The liver showed inflammatory infiltration, cytoplasmic inclusion bodies, vacuolar degeneration, fatty degeneration, pyknosis, karyolysis, distorted pancreatic area, and piecemeal necrosis, among other pathological symptoms. The study concluded that the effluent, even in greatly diluted form, was highly toxic and the severity of responses depended on the length of exposure.