bluuebunny/crossref_metadata_2025 huggingface dataset:
THE RELATIONSHIP BETWEEN THE AVAILABILITY OF LACTATION FACILITIES, MOTHERS' KNOWLEDGE, AND EXCLUSIVE BREASTFEEDING AMONG FEMALE FACTORY WORKERS IN SIDOARJO DISTRICT
Authors: Rizqa Billah , Umbul W Chatarina
Published: November 2021

ABSTRACTAccording to UNICEF, in 2013 there were 136,700,000 live births, but only about 32.6% of these babies received breast milk exclusively. In developing countries, only about 39% of mothers breastfeed exclusively. Indonesia has targetted for 80% exclusive breastfeeding. However, it has not been achieved. A large number of women in the workforce and the unavailability of breastfeeding facilities are among the factors influencing the low coverage of exclusive breastfeeding in Indonesia. In addition, maternal knowledge is also a contributing factor for exclusive breastfeeding practices This study aims to analyze the relationship between the availability of lactation facilities and maternal knowledge with exclusive breastfeeding. The execution of this research was conducted quantitatively with the descriptive research type. The design of this study is case-control. The study’s population were female factory workers who had babies in Sidoarjo District. The sample size is 42 case samples and 42 control samples. The research sample was taken using a simple random sampling technique. The data was retrieved through survey methods with questionnaires. The results of the study show that there is no relationship between knowledge and exclusive breastfeeding (p = 0.200) and there is a relationship between the availability of lactation facilities and exclusive breastfeeding (p = 0.049). Mothers who work in factories with lactation facilities have a 2.667 times greater opportunity to give exclusive breastfeeding to their babies than mothers without access to lactation facilities (OR = 2.667). The researchers suggest factories to provide lactation facilities and visitation activities by the local health office.Keywords: Exclusive breastfeeding, Lactation facilities, Mother's knowledge
THE ROLE OF INDIVIDUAL AND COMMUNITY FACTORS ON THE USE OF LONG-TERM CONTRACEPTIVE METHODS (MKJP) ON WOMEN OF REPRODUCTIVE AGE COUPLES IN INDONESIA 2018
Authors: Saki Vernonia Yora , Deniati Ema Novita , Besral Besral , Ekoriano Mario
Published: November 2021

ABSTRACTThis research discussed the role of individual and community factors on the use of Long Term Contraceptive Method (MKJP) in women of reproductive age couple by region in Indonesia in 2017. The study design follows the advanced analysis design of RPJMN BKKBN survey data that was cross-sectional design. The sample of research on RPJMN survey was women of reproductive age couple. Data were analyzed by Multilevel Logistic Regression analysis. The results showed that the Proportion of women of reproductive age couples using long-term contraceptive methods (MKJP) in Java Bali (27.2%) more than high than Outside of Java Bali I (22.9%) and Outside of Java Bali II (20.2%). Multilevel analysis results showed that there are variations between provinces of MKJP used in women of reproductive age couple in the area of Indonesia Java Bali and Outside of Java Bali I of 1.4 and 1.3 in the area of Outside of Java Bali II. Based on the results, BKKBN recommended implementing MKJP usage program that takes into account the area aspect and cannot be uniform for all provinces in Indonesia. Keywords: Contraception MKJP, Women WUS
ANALISIS EKUITAS MEREK GULA PASIR GULAKU DAN GUPALAS
Authors: Bakhtiar Darul
Published: November 2021

Introduction: This study aims to study the various elements of brand equity (brand equity) granulated sugar products, such as: brand awareness, brand association, brandperceived quality, and brand loyalty by comparing two brands of sugar products are Gulaku and Gupalas. Gulaku as first mover advantages which the first player to enter a particular industry is often considered to have the first opportunity to build market share since 2002, while Gupalas is a product that has just appeared in 2011.Methods: The sampling method used is purposive sampling with the number of respondents who were taken as the sample in the study of100 people consumers of sugar, especially housewives who are in theMadiun area. Analyzer used in this research is the analysis of the meandifference test through t test and a confirmation through Manova test.Results: Brand equity research results indicate that Gulaku have higherbrand equity than Gupalas. The difference was due to the three elements of brand equity include brand awareness, brand associations and brandloyalty of Gulaku much higher than Gupalas. While Gupalas Gulaku only be offset in terms of perceived quality alone.Conclusion and suggestion: This study is used as input Gupalasmanufacturers namely PT. Nusantara Plantation XI as brand equityevaluation of Gupalas include brand equity, which is supposed to be improved.
PENGARUH KUALITAS AUDIT TERHADAP KEPUASAN KLIEN
Authors: Mika Marsely Mika Marsely
Published: November 2021

The purpose of this research is to examine the effect of audit quality on client satisfaction. The unit of analysis in this study is the PNPM Mandiri Urban LKM in Sidoarjo Regency, amounting to 291 MFIs scattered in all villages / wards in Sidoarjo Regency. PNPM Mandiri Urban LKM is a nonprofit organization that aims to alleviate poverty. The sample in this study consisted of 32 economic village village (faskel) facilitators who overshadowed 291 LKM and also acted as counterpart auditors during the audit. The number of questionnaires distributed was 32 copies and 32 returned questionnaires or as many as 100%. The data analysis technique used in this research is Multiple Linear Regression Analysis.The results of this study indicate that the understanding attribute of the client industry and responsiveness to client needs has a significant effect on client satisfaction. Meanwhile, the attributes of competence, independence, caution of the audit team, KAP commitment to quality, high ethical standards and skepticism of the audit team did not have a significant effect on client satisfaction. The limitation in this study is that the sample used only comes from one party, namely the auditee. It is recommended that further research should use samples from both parties between the auditee and the auditor so that more valid answers can be obtained
KONSERVATISME AKUNTANSI DAN KEPERCAYAAN INVESTOR
Authors: Anita Tanti
Published: November 2021

This research intended to test the influence of accounting conservatism explanations such as contracting, litigation, taxation, and regulation to investor trust. In this case, the indicator of the investor trust can be seen from the stock return. A number of manufacturing companies registered in Indonesia stock exchange from year 2008 to 2012 was used as samples in this research. The test of the influence of accounting conservatism explanations to stock return has been done by using double regression analysis. Based on the result of the test, the accounting conservatism explanations for contracting, litigation and regulation has no significant influence to stock return. On the contrary, it has positively significant influence to taxation.
THE REMOTE AND AGILE AUDITING: A FRAUD PREVENTION EFFORT TO NAVIGATE THE AUDIT PROCESS IN THE COVID-19 PANDEMIC
Authors: Koerniawati Dwi
Published: November 2021

This research aims to identify and navigate how auditors are able to find solutions to various obstacles that occurred in the audit process during the Covid-19 pandemic. This study uses a qualitative (non-positivistic) approach with this type of research focusing on systematic exploratory research of a pandemic covid-19 phenomenon and using descriptive analysis techniques and anticipatory condensation data from remote and agility audits. The method of data collection is carried out by interviews, observations and documentation with purposive sampling as a method of selecting research sources. Source triangulation and triangulation techniques are selected by researchers to ensure the validity of the data. The research sources are external and internal auditors from KAP leading in Indonesia and are foreign affiliated audit firm and internal auditors from companies that implement internal control of 5 people. The result of this study is that remote audit and agility audit can be used as a solution to navigate problems in carrying out the audit process and business disruption in the time of the covid-19 pandemic crisis. Remote Audit and Agility audit is an alternative way that can be used as a reference in conducting the audit process during the Covid-19 pandemic to still be able to realize Good corporate governance (GCG) and can quickly detect fraud. Real contributions that can be utilized by auditors are helping auditors find solutions in solving problems such as supervision in the form of asset misappropriation cases ranging from cash theft, misappropriation of cash receipts, fraud during disbursement, misuse of company asset inventory. and theoretical contributions to strengthen and enrich fraud pentagon theory, in addition, this research can also formulate a framework to realize Good corporate governance (GCG) and post crisis such as COVID-19.
Estimation of Leaf Area Index in vineyards by analysing projected shadows using UAV imagery
Authors: Vélez Sergio , Poblete-Echeverría Carlos , Rubio José Antonio , Vacas Rubén , Barajas Enrique
Published: November 2021

A few decades ago, farmers could precisely monitor their croplands just by walking over the fields, but this task becomes more difficult as farm size increases. Precision viticulture can help better understand the vineyard and measure some key structural parameters, such as the Leaf Area Index (LAI). Remote Sensing is a typical approach to monitoring vegetation which measures the spectral information directly emitted and reflected from vegetation. This study explores a new method for estimating LAI which measures the projected shadows of plants using UAV (unmanned aerial vehicle) imagery. A flight mission over a vineyard was scheduled in the afternoon (15:30 to 16:00 solar time), which is the optimal time for the projection of vine shadows on the ground. Real LAI was measured destructively by removing all the vegetation from the area. Then, the projected shadows in the image were detected using machine learning methods (k-means and random forest) and analysed at pixel level using a customised R code. A strong linear relationship (R² = 0.76, RMSE = 0.160 m² m-2 and MAE = 0.139 m² m-2) was found between the shaded area and the LAI per vine. This is a quick and simple method, which is non-destructive and gives accurate results; moreover, flights can be scheduled during other periods of the day than solar noon, such as in the morning or afternoon, thus enabling pilots to extend their working day. Therefore, it may be a viable option for determining LAI in vineyards trained on Vertical Shoot Positioned (VSP) systems.
Tillage Practices in Potato (Solanum tuberosum L.) Production: A Review
Authors: Djaman Koffi , Koudahe Komlan , Koubodana Houteta D. , Saibou Aminou , Essah Samuel
Published: November 2021

Potato is one of the main crops grown worldwide under different climatic conditions. Potato is conventionally produced under intensive tillage practices under the same or different soil types. Research has shown some contrasting effects of the tillage practices on the soil properties, crop growth, yield, and quality. Under the reducing available freshwater for food production, soil management practices are more targeting conservation and system sustainability. It is therefore critical to revisit literature on the tillage practices and their impact on the soil, crop, and crop yield. This review presents research results of studies conducted exclusively on potatoes comparing different types of tillage practices and is a valuable source of information for potato growers and scientists as it is not only focused on the impact of tillage practices on soil properties but also on potato tuber yield and grade, tuber specific gravity, and the impact of tillage practices on diseases in potatoes.
Circulating Phylotypes of White Spot Syndrome Virus in Bangladesh and Their Virulence
Authors: Hasan Mehedi Mahmudul , Hoque M. Nazmul , Ahmed Firoz , Haque Md. Inja-Mamun , Sultana Munawar , Hossain M. Anwar
Published: November 2021

White Spot Syndrome Virus (WSSV) has emerged as one of the most prevalent and lethal viruses globally, and infects both shrimps and crabs in the aquatic environment. This study aimed to investigate the occurrence of WSSV in different ghers of Bangladesh and the virulence of the circulating phylotypes. We collected 360 shrimp (Penaeus monodon) and 120 crab (Scylla sp.) samples from the South-East (Cox’s Bazar) and South-West (Satkhira) coastal regions of Bangladesh. The VP28 gene-specific PCR assays and sequencing revealed statistically significant (p < 0.05, Kruskal Wallis test) differences in the prevalence of WSSV in shrimps and crabs between the study areas (Cox’s Bazar and Satkhira), and over the study periods (2017-2019). The mean Log load of WSSV varied from 8.40 (Cox’s Bazar) to 10.48 (Satkhira) per gram of tissue. The mean values for salinity, dissolved oxygen, temperature and pH were 14.71±0.76 ppt, 3.7±0.1 ppm, 34.11±0.38˚C and 8.23±0.38, respectively in the WSSV-positive ghers. The VP28 gene-based phylogenetic analysis showed an amino-acid substitution (E→G) at 167th position in the isolates from Cox’s Bazar (referred to as phylotype BD2) compared to the globally circulating one (BD1). Shrimp PL artificially challenged with BD1 and BD2 phylotypes with filtrates of tissue containing 0.423 X 109 copies of WSSV per mL resulted a median LT50 value of 73 hrs and 75 hrs, respectively. The in-vivo trial showed higher mean Log WSSV copies (6.47±2.07 per mg tissue) in BD1 challenged shrimp PL compared to BD2 (4.75±0.35 per mg tissue). Crabs infected with BD1 and BD2 showed 100% mortality within 48 hrs and 62 hrs of challenge, respectively with mean Log WSSV copies of 12.06±0.48 and 9.95±0.37 per gram tissue, respectively. Moreover, shrimp antimicrobial peptides (AMPs) penaeidin and lysozyme expression was lower in BD1 challenged group compared to BD2 challenged shrimps. These results collectively demonstrated that relative virulence properties of WSSV based on mortality rate, viral load and expression of host immune genes in artificially infected shrimp PL could be affected by single aa substitution in VP28.
Blue-LED Calibration on DOAS System to Measure Nitrogen Dioxide Emission Compared with USEPA Method 7B Standard
Authors: Fatkhurrahman Januar Arif , Sari Ikha Rasti Julia
Published: November 2021

Air polution level measurement sometime needs tricky instrumentation, costly, and use chemical reagent that could bad impact to environment, it also time consuming for analysis. In other hand, air polution level measurement, include nitrogen dioxide (NO2) needs accuracy, rapid and environment friendly for its analysis and measurement. Differential Optical Absorption Spectroscopy (DOAS) develop as spectrum measurements both UV and visible, transmitted by specific canal using absorption Lambert Beer’s Law principal. On this basic method, NO2 measurement needs light source with 330 – 500 nm wavelength, it is possible to use cheap blue-LED for this measurement. This research intends to calibrate prototype instrumentation for measuring NO2 by DOAS based using Blue-LED (375 nm) passed in continual gas container. NO2 emission simulated in laboratory scale by reacting copper (Cu) with nitric acid (HNO3) result NO2 gas formation. Blue-LED spectrum analysed by compact CCD Spectrometer for its absorbance spectrum, then calibrated with NO2 measurement using USEPA Method 7B standard that is commonly used in testing laboratory as standard method for NO2 measurement. It has good corelation between spectrum absorbance in CCD Spectrometer to USEPA Method 7B with more than 95% linierity. As rapidity of this measurement and shown good accuracy, more development for this method could carry fast, accurate, cheap, also environmentally friendly method for NO2 measurement.
Delineation of the Ancestral Tus-Dependent Replication Fork Trap
Authors: Toft Casey , Moreau Morgane , Perutka Jiri , Mandapati Savitri , Enyeart Peter , Sorenson Alanna , Ellington Andrew D. , Schaeffer Patrick
Published: November 2021

In Escherichia coli, DNA replication termination is orchestrated by two clusters of Ter sites forming a DNA replication fork trap when bound by Tus proteins. The formation of a ‘locked’ Tus-Ter complex is essential for halting incoming DNA replication forks. However, the absence of replication fork arrest at some Ter sites raised questions about their significance. In this study, we examined the genome-wide distribution of Tus and found that only the six innermost Ter sites (TerA-E and G) were significantly bound by Tus. We also found that a single ectopic insertion of TerB in its non-permissive orientation could not be achieved, advocating against a need for ‘back-up’ Ter sites. Finally, examination of the genomes of a variety of Enterobacterales revealed a new replication fork trap architecture mostly found outside the Enterobacteriaceae family. Taken together, our data enabled the delineation of a narrow ancestral Tus-dependent DNA replication fork trap consisting of only two Ter sites.
Potential Prebiotic and Anti-Obesity Effects of Polysaccharides from Codium fragile
Authors: Oh Suwon , Kim Sungkeun , Jung Kyoojin , Pham Thi Ngoc Anh , Yang Seungwhan , Ahn Byungjae
Published: November 2021

Polysaccharides from marine algae exhibit beneficial biological activities. In this study, we examined the effect of polysaccharides from Codium fragile (PCF) on prebiotic and anti-obesity activity. PCF increases the growth of specific beneficial microbial populations with concomitant decrease in pathogenic microbes. Further, total phenolic content (TPC), total flavonoid content (TFC), and DPPH radical scavenging activity (DPPH activity) after fermentation with PCF as carbon source were higher than for the glucose as control. Moreover, PCF inhibited adipocyte differentiation by inducing differentiation-related factors when the induction of 3T3-L1 preadipocytes into adipocytes was induced. Therefore, we suggest that PCF can be used as prebiotic material with anti-obesity for human health.
Polypropylene Graft Poly(Methyl Methacrylate) Graft Poly(N-Vinylimidazole) as a Smart Material for pH-Controlled Drug Delivery
Authors: López-Saucedo Felipe , López-Barriguete Jesús Eduardo , Flores-Rojas Guadalupe Gabriel , Gómez-Dorantes Sharemy , Bucio Emilio
Published: November 2021

Surface modification of polypropylene (PP) films is achieved using gamma-irradiation-induced grafting to proffer with antimicrobial activity. The copolymer was obtained through a versatile two-step route; pristine PP is exposed to gamma rays and grafted using methyl methacrylate (MMA), then N-vinylimidazole (NVI) is grafted onto the copolymer PP-g-MMA by simultaneous irradiation. The characterization included Fourier-Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscope (SEM), Thermogravimetric Analysis (TGA), X-ray Photoelectron Spectroscopy (XPS), and physicochemical analysis of swelling and contact angle. The copolymer (PP-g-MMA)-g-NVI was loaded with vancomycin, and the drug released was quantified by UV-vis spectrophotometry at different pH. The surface of (PP-g-MMA)-g-NVI exhibited pH-responsiveness and moderate hydrophilicity, suitable properties for controlled drug release.
Paving Therapeutic Avenues for FOXG1 Syndrome: Untangling Genotypes and Phenotypes from a Molecular Perspective
Authors: Akol Ipek , Gather Fabian , Vogel Tanja
Published: November 2021

Development of the central nervous system (CNS) depends on accurate spatiotemporal control of signalling pathways and transcription programs. Forkhead Box G1 (FOXG1) is one of the master regulators that plays fundamental roles in forebrain development, from the timing of neurogenesis to the patterning of the cerebral cortex. Mutations in the FOXG1 gene cause a rare neurodevelopmental disorder called FOXG1 syndrome, also known as congenital form of Rett syndrome. Patients presenting with FOXG1 syndrome manifest a spectrum of phenotypes ranging from severe cognitive dysfunction and microcephaly to social withdrawal and communication deficits with varying severities. To develop and improve therapeutic interventions, there has been considerable progress towards unravelling the multi-faceted functions of FOXG1 in neurodevelopment and pathogenesis of FOXG1 syndrome. Moreover, recent advances in genome editing and stem cell technologies, as well as increased yield of information from high throughput omics opened promising and important new avenues in FOXG1 research. In this review, we provide a summary of clinical features and emerging molecular mechanisms underlying FOXG1 syndrome, and explore disease-modelling approaches in animals and human-based systems to highlight prospects of research and possible clinical interventions.
Review on Chemical Graph Theory and Its Application in Computer-Assisted Structure Elucidation
Authors: Yirik Mehmet Aziz , Colpan Kumsal Ecem , Schmidt Saskia , Sorokina Maria , Steinbeck Christoph
Published: November 2021

The chemical graph theory is a subfield of mathematical chemistry which applies classic graph theory to chemical entities and phenomena. Chemical graphs are main data structures to represent chemical structures in cheminformatics. Computable properties of graphs lay the foundation for (quantitative) structure activity and structure property predictions - a core discipline of cheminformatics. It has a historic relevance for natural sciences, such as chemistry, biochemistry and biology, and is in the heart of modern disciplines, such as cheminformatics and bioinformatics. This review first covers the history of chemical graph theory, then provides an overview of its various techniques and applications for CASE, and finally summarises modern tools using chemical graph theory for CASE.
Fear, Peer Pressure, or Encouragement: Identifying Levers for Nudging Towards Healthier Food Choices in Multi-Cultural Singapore
Authors: Wan Kum-Seong , Choo Bryan Jun-Keat , Chan Kwok-Fong , Yeo Joshua Yi , Tan Clare Shu-Lin , Quek Boon-Kiat , Gan Samuel Ken-En
Published: November 2021

With roots beyond behavioural economics to psychology, nudges can be applied for influencing healthy behaviours such as food choice and portions to decrease obesity for better public health outcomes. However, the effectiveness of the type of nudges are contentious with conflicting literature. In this pilot study, we conducted a 23-day study surveying the food choices that included portion, locus of control, demographic data, and psychological measures of personality, perceived stress, narcissism, regulatory focus, food choice motive and dietary restraint, with the participants given four intervention conditions of 12 instant messaging sent every two days through WhatsApp. The messages were either factual (control), focused on consequences, through social comparison, or persuasive. Running over the COVID19 pandemic, 17 participants completed the full surveys showing significant effects between the experimental conditions with the psychological parameters except for diet confidence and extraversion and conscientiousness, as well as cognitive restraint. We found BMI and waistline measurements to be suitable measurements, with promising results from the fear and social comparison nudges for food-related behaviours and exercise. Our pilot findings have implications to the use of nudges upon which future studies investigating psychological factors can build on.
Physical Activity and BMI before and after the Situation Caused by COVID-19 in Upper Primary School Pupils in Czech Republic
Authors: Pysna Jana , Suchý Jiří , Pyšný Ladislav , Cihlář David , Petrů Dominika , Müllerová Lenka Hajer , Čtvrtečka Luděk
Published: November 2021

Regular physical activity is a very important factor in the healthy development of an individual and an essential part of a healthy lifestyle. However, today's population still suffers from insufficient amount of exercise caused mainly by technical progress and often inappropriate conditions for practicing sports. In relation to this, we are grappling with a steady increase in obesity. During the COVID-19 pandemic, conditions for regular physical activity became even more unfavourable, with the declaration of a state of emergency and anti-pandemic measures leading to the closure of sports grounds and sporting competitions. In our research survey, we attempted to determine whether there would be changes in physical activity and BMI before and after the situation caused by the COVID-19 disease in upper primary school pupils in the Czech Republic. Using a questionnaire survey of a sample of children (n =1456), we found that already before the pandemic, 69% of the observed sample had not met the recommended amount of physical activity and only 67% of the sample was of normal weight. After the end of the anti-pandemic measures, the observed values deteriorated even more. There was a significant decrease in children with normal weight (by 7.5%) and an increase in children with Class 1 obesity. At the same time, we saw a significant decrease in children doing sports.
Benefits of Defining Geological Sensitive Zones in the Mitigation of Disasters Along Earthquake Fault Zones in Taiwan – The Case of Milun Fault
Authors: Chu Tyan-Ming , Huang Wen-Jeng , Lin Tsung-Yi , Lu Shih-Ting , Liu Yen-Chiu , Chiang Cheng-Shing , Chang Yi-Huei ,   Pro-Vision Environmental Engineering Corporation 9F-4, No.65, Songde Road, Xin-Yi District, Taipei, Taiwan,   Graduate Institute of Applied Geology, National Central University, Taoyuan, Taiwan,   Department of Geography, National Taiwan Normal University, Taipei, Taiwan,   Central Geological Survey, Ministry of Economic Affairs (MOEA), New Taipei, Taiwan,   921 Earthquake Museum of Taiwan, National Museum of Natural Science, Taichung, Taiwan,   Systems and Technology Corporation, New Taipei, Taiwan
Published: November 2021

In Taiwan, the main purpose of earthquake fault zone legislation is to prevent earthquake-related disasters around the surface traces of active faults, particularly in urban areas. Here, the Geologically Sensitive Area (GSA) of the Milun Fault (Milun Earthquake Fault Zone) is used as an example to reveal the importance of such legislation. Field data collected along the Milun Fault before and after the 2018 Hualien Earthquake were used to reveal the reappearance of damages within the GSA. The 2018 Hualien Earthquake represents one of the shortest recurrence intervals (67 years) among all major faults in Taiwan. Most of the surface ruptures and damaged buildings in Hualien City were within the Milun Fault GSA and concentrated on the hanging wall of the fault. Moreover, 61% (91/148) of the damaged buildings and 83% (692/835) of the surface ruptures occurred within 100 m of the fault line. The results of this study demonstrate the importance of defining GSAs of active faults for mitigating earthquake hazards.
Community Empowerment Program in Overcoming the Problem of Disease in Tomajiko Kelurahan, Pulau Hiri District
Authors: Patilaiya Hairudin La , Ishak Sitti Nurhidayanti
Published: November 2021

Penyakit Demam Berdarah Dengue (DBD) merupakan salah satu permasalahan bagi negara-negara yang beriklim tropis seperti di Indonesia. Melonjaknya angka kematian akibat penyakit ini setiap tahun menjadikan sebuah peristiwa luar biasa. Untuk mengatasi permasalahan ini, tim Ibm UMMU berupaya melakukan kegiatan pengendalian DBD dengan melakukan sosialisasi DBD dan gerakan PSN (Pemberantasan Sarang Nyamuk) dengan 3M plus yaitu Menguras, Menutup dan Mengubur. Program ini bertujuan untuk meningkatkan pemahaman masyarakat terhadap resiko penyakit DBD serta kesadaran masyarakat mengenai pola hidup bersih. Metode pemberdayaan yang digunakan yaitu pemberian literasi dan praktek Pemberantasan Sarang Nyamuk. Program ini terbukti dapat meningkatkan pemahaman siswa dalam pemberantasan sarang nyamuk yang menyebabkan penyakit DBD. Dengan adanya program ini, masyarakat kelurahan Tomajiko kecamatan Pulau Hiri diharapkan dapat selalu menjaga lingkungan agar tetap bersih untuk menghindari penyakit DBD. Hasil dari program ini diharapkan dapat ditiru oleh beberapa desa sekitar kepulauan Hiri yang memiliki karakteristik demografi yang sama.
Skills Improvement for Local Integrated Healthcare Post (Posyandu) Cadres and Housewives through Training on Making Healthy Snacks Based on Fisheries Waste in Benda Baru, South Tangerang
Authors: Alitimbul Mariani , Artanti Guspri Devi
Published: November 2021

Program yang ditujukan untuk meningkatkan keterampilan ibu rumah tangga dan kader Posyandu di  Kelurahan Benda Baru Kabupaten Tangerang Selatan dalam bentuk pelatihan pembuatan jajanan sehat  berbasis limbah perikanan berupa kulit udang yang merupakan program pengabdian kepada masyarakat yangditujukan kepada sebanyak 25 orang ibu rumah tangga dan kader Posyandu. Hasil yang diharapkan dari  pelatihan adalah peningkatan keterampilan sebagai upaya untuk membentuk/mengembangkan sekelompok  masyarakat yang mandiri secara ekonomi dan sejahtera. Luaran dalam pengabdian masyarakat adalah 

produk jajanan dari limbah perikanan, modul jajanan sehat berbasis limbah perikanan, publikasi ilmiah dan  publikasi kegiatan pembuatan jajanan sehat berbasis limbah perikanan berupa platform Youtube. Metode  yang digunakan dalam kegiatan ini ceramah, demonstrasi, serta praktek bersama-sama dengan peserta  pelatihan membuat jajanan sehat dengan bahan dari limbah perikanan berupa kulit udang. Hasil pelatihan  peningkatan keterampilan pembuatan jajanan sehat berbasis limbah perikanan diikuti dengan baik oleh  peserta dengan membuat produk simping dan telor gabus asin yang menggunakan bahan tepung dari limbah  kulit udang.
Content of nutrients and limitation of phytoplankton primary production in the specially protected natural area “Cape Martyan” (Black Sea)
Authors: Egorov V. N. , Bobko N. I. , Marchenko Yu. G. , Sadogurskiy S. Ye.
Published: November 2021

The results are presented of studying the content of nitrogen compounds and mineral phosphorus, as well as phytoplankton primary production (PPP). The research was carried out in 2017–2019 in the marine area of the specially protected natural area “Cape Martyan” located on the southern coast of Crimea (Black Sea). As found, during summer in the surface seawater layer, PPP can be limited by both nitrogen and phosphorus. The dependence of PPP variation on the concentration of total nitrogen in water is not significant, while the dependence on the concentration of phosphorus is significant. It is shown that during the entire annual cycle, concentrations of nitrites, nitrates, ammonium, and mineral phosphorus vary but remain within the limits that do not lead to water hypereutrophication. A high ecological significance of precipitation was revealed: the related increase in PO4 concentration caused a transition in PPP limitation mode from phosphorus to nitrogen one. Using theoretical concepts, it is substantiated that, under oligotrophic conditions, an increase in the concentration of the substrate limiting PPP in water results in an increase in the rate of its uptake from the environment in accordance with the negative feedback of natural regulation of ecosystem homeostasis. Under conditions of eutrophication, the effect of production processes on water conditioning by the factor of nutrients decreases.
On the presence of the spinner shark Carcharhinus brevipinna (Müller & Henle, 1839) (Chondrichthyes: Carcharhinidae) in Maldivian waters
Authors: Russo F. , De Maddalena A.
Published: November 2021

We present the first confirmed report on the presence of spinner shark, Carcharhinus brevipinna, in Maldivian waters. The species was observed in front of Kooddoo’s harbour, in Villingili pass, Northern Huvadhoo Atoll, Southern Maldives in March 2020.
Polypharmacy and Potentially Inappropriate Medications in Stroke Rehabilitation: Prevalence and Impact
Authors: Matsumoto Ayaka , Yoshimura Yoshihiro , Nagano Fumihiko , Bise Takahiro , Kido Yoshifumi , Shimazu Sayuri , Shiraishi Ai
Published: November 2021

BackgroundEvidence is scarce regarding the polypharmacy and potentially inappropriate medications (PIMs) in rehabilitation medicine.AimTo investigate the prevalence and impact on outcomes of polypharmacy and PIMs in stroke rehabilitation.MethodsA retrospective cohort study was conducted with 849 older inpatients after stroke.Polypharmacy was defined as six or more medications, and PIMs were defined based on Beers criteria 2019. Study outcomes included Functional Independence Measure (FIM)-motor, FIM-cognitive, energy intake, dysphagia, length of hospital stay and the rate of home discharge. To consider the impact of pharmacotherapy during rehabilitation, multivariate analyses were used to determine whether the presence of polypharmacy or PIMs at discharge was associated with outcomes.ResultsAfter enrollment, 361 patients (mean age 78.3 ± 7.7 years; 49.3% male) were analyzed. Polypharmacy was observed in 43.8% and 62.9% of patients, and any PIMs were observed 64.8% and 65.4% of patients at admission and discharge, respectively. The most frequently prescribed PIMs included antipsychotics, benzodiazepines, and proton pump inhibitors. Polypharmacy was negatively associated with FIM-motor score (β = -0.072, P = 0.017), FIM-cognitive score (β = -0.077, P = 0.011), energy intake (β = -0.147, P = 0.004), and home discharge (OR: 0.499; 95% CI: 0.280, 0.802; P = 0.015). PIMs were negatively associated with energy intake (β = -0.066, P = 0.042) and home discharge (OR: 0.452; 95% CI: 0.215, 0.756; P = 0.005).ConclusionsPolypharmacy and PIMs are commonly found among older patients undergoing stroke rehabilitation. Moreover, polypharmacy and PIMs are negatively associated with outcomes.
“It’s Changed My Life Not To Have the Continual Worry of Being Warm” – Health and Wellbeing Impacts of a Local Fuel Poverty Programme: A Mixed-Methods Evaluation
Authors: Sawyer Alexandra , Sherriff Nigel , Darking Mary , Huber Jörg W.
Published: November 2021

Background
Living in a cold home and being fuel poor can contribute to adverse physical and mental health. Energy efficiency interventions are considered the simplest ways of tackling fuel poverty and preventing associated negative health, wellbeing, and socio-economic consequences. The overall aim of the current study was to provide a greater understanding of the impact of a locally administered programme, which funded the installation of major heating/insulation measures in areas of high fuel poverty, on the health and wellbeing of beneficiaries of the programme.
Methods
A mixed-methods approach to explore the health and wellbeing impacts of a fuel poverty programme in East Sussex that took place between October 2016 and March 2018. Beneficiaries completed the Warwick-Edinburgh Mental Wellbeing Scale before and after any heating/insulation work had been completed in their home. Beneficiaries were also asked to retrospectively rate their health pre- and post-installation. Interviews with 23 beneficiaries of the programme were conducted to explore in-depth the impact of the programme on people’s health and wellbeing and the wider social determinants of health.
Results
A major heating/insulation measure was installed in 149 homes. The majority of measures installed were boilers (57.7%) and new central heating systems (32.2%). Self-rated health and wellbeing were significantly higher post-installation. Interviewees described clear examples of the positive impacts on physical health and wellbeing such as fewer chest infections, reduced pain, feeling less anxious and depressed, and generally feeling happier and more relaxed. Interviews also highlighted broader areas of impact such as reduced social isolation and increased use of domestic space. Many of the beneficiaries also reported a reduction in their energy bills since their new heating systems had been installed.
Conclusions
The findings from the evaluation suggest that the installation of major heating or insulation measures such as new boilers have substantial benefits for the health and wellbeing of beneficiaries. The findings also suggest that the programme had a positive impact on wider determinants of health including reduction in stress and isolation that are likely to be part of the pathways between fuel poverty interventions and mental and physical health outcomes.
Green Complexity, Economic Fitness, and Environmental Degradation: Evidence from U.S. State-Level Data
Authors: Çınar İbrahim Tuğrul , Korkmaz İlhan , Şişman Muhammet Yunus
Published: November 2021

Green production is one of the major debates as environmental degradation poses threats globally. The paper attempts to explore the relationship between green economy and environmental quality by using Economic Fitness approach. We develop a Green Complexity Index (GCI) dataset consists of 290 traded green-labeled products for the US States between 2002 and 2018. We analyze the environmental performance of green production using the GCI data at the sub-national level. Findings indicate that exporting more complex green products has insignificant effects on local (i.e., Sulfur dioxide, Particulate Matter 10) and global polluters such as Carbon dioxide (CO2), even accounting for per capita income. Yet, overall economic complexity has a significant negative impact on the emission levels implying that sophisticated production significantly improves environmental quality in the US. The insignificant impact of GCI on environmental degradation suggests that green product classifications should incorporate the production and end-use stages of goods to limit the adverse environmental effects of green-labeled products. The study, therefore, provides policy implications for green industrial policies.JEL codes: O18, Q56, R11
Somatic embryogenesis from young inflorescences of the giant bamboo Dendrocalamus asper (Schult f.) Backer ex Heyne
Authors: Ornellas Thiago Sanches , Fritsche Yohan , Medina Edison Cardona , Guerra Miguel Pedro
Published: November 2021

Bamboos are an important worldwide non-timber forest product with current rising interest due to their environmentally friendly applications. Besides the consolidated uses of the sweet shoots and culms for structural uses, Dendrocalamus asper is an imposing ornamental bamboo for horticulture. The present work aimed to establish in vitro calli culture and plant regeneration through somatic embryogenesis starting from young inflorescences of the giant bamboo, D. asper. Pre-anthesis inflorescences were collected, disinfested, and subjected to callus induction on MS basal medium supplemented by 0 µM, 9 µM, 18 µM, 27 µM, and 36 µM of 2,4-D in combination with 9 µM of 2-iP or 9 µM Kin. The different obtained calli types were characterized and subcultured in 0 µM, 4.5 µM, 9 µM, and 18 µM of 2,4-D in combination with 9 µM of both cytokinins for multiplication and differentiation. Additionally, the explant incision and its inoculation orientation onto culture media were tested for callus induction improvement. The 2,4-D was essential for callus induction, and its combination with both cytokinins resulted in embryogenic callus induction and further somatic embryos regeneration. The subsequent reduction of this auxin to 4.5 µM resulted in somatic embryo maturation. Somatic embryos transferred to a plant growth regulator-free medium resulted in plantlet conversion. The present work showed the feasibility of using inflorescences as explants and the efficiency of using the 2-iP in combination with 2,4-D to callus induction and in vitro bamboo plant regeneration through somatic embryogenesis.
Efficient Adsorption of Pb(II) by Sodium Dodecyl Benzene Sulfonate Intercalated Calcium Aluminum Hydrotalcites: Kinetic, Isotherm and Mechanisms
Authors: Zeng Rongying , Tang Wenqing , Zhou Qianyi , Liu Xing , Liu Yan , Wang Shuzhan , Chen Zhen , Yi Nengzhong , Wang Zefen , Chen Jun
Published: November 2021

CaAl-LDHs and sodium dodecyl benzene sulfonate (SDBS) intercalated CaAl-LDHs (SDBS-CaAl-LDHs) was acquired by co-precipitation. The two samples were characterized by XRD, XPS, FT-IR, TG and SEM. The factors affecting adsorption (pH, adsorption time，initial concentration) of Pb2+ by two adsorbents were studied. The results showed that SDBS-CaAl-LDHs has higher adsorption ability for lead ions removal than that of CaAl-LDHs. Kinetic data for lead ions were in keeping with pseudo-2nd-order model, the adsorption isotherms followed Langmuir and Freundlich isotherm model for CaAl-LDHs. The adsorption by SDBS-CaAl-LDHs were in keeping with the pseudo-second-order kinetic and Langmuir model, suggesting lead ions were chemical adsorption. Adsorption was thought to form through Pb species in the precipitates, such as formation of hydroxides and carbonates for lead ions by XRD analysis. Therefore, based on the structural and morphological features, as well as XRD, XPS and SEM, the lead ion adsorption mechanism on SDBS-CaAl-LDHs involved the electrostatic attraction, precipitation, complexation and ion exchange. The Langmuir adsorption capacities for SDBS-CaAl-LDHs were found as 797.63, 828.76, 854.29 mg×g−1 at 293k, 303k, 313k, respectively, when the pH is about 5.2, and thus, making it a highly economical adsorbent for the treatment of contaminated water.
Reasonable Layout of Roadway Based on PSO-AHP Optimization Algorithm Under Three-Dimensional Stress Field
Authors: Zhao Hongbao , Cheng Hui , Zhang Chi , Zhang Yixiao
Published: November 2021

Reasonable roadway layout is the fundamental measure to reduce the difficulty of roadway support and improve the stability of surrounding rock. The particle swarm optimization and analytic hierarchy process (PSO-AHP) algorithm of reasonable layout of roadway under the three-dimensional field was proposed, and an engineering verification was carried out in Weijiadi coal mine. The results showed that, The dip angle α1 and azimuth angle α2 affect the distribution of the deviatoric stress of the roadway surrounding rock. Under different stress field, the sensitivity of surrounding rock to α1 and α2 are different. Changing the more sensitive layout parameters can minimize the deviatoric stress and improve the stability of roadway. The PSO-AHP optimization algorithm takes the deviatoric stress as the index to calculate the layout parameters of different parts of the roadway, and then determines the optimal layout parameters through the evaluation function. The roadway of 1104 working face was arranged with the optimal parameters obtained by PSO-AHP optimization algorithm. Compared with the original layout scheme, the deviatoric stress of surrounding rock was reduced and the position of maximum deviatoric stress is transferred. The optimum layout of roadway was combined with an asymmetric support which had a good application effect.
Effect of Monthly Evaluations on Irrational Rates of Antimicrobial Drug Prescription in Outpatient and Emergency Departments
Authors: Yang Qiong , Yuan Fangfang , Li Li , Jin Jianfeng , He Junhong
Published: November 2021

Reduction of the excessive rate of antibiotic prescription is needed to curb antibiotic resistance. This retrospective study was conducted to verify whether monthly evaluations of antibiotic prescriptions could improve clinical antibiotic use in outpatient and emergency departments. Every month, from July 2016 to June 2019, 25% of the antibacterial prescriptions from the outpatient and emergency departments in our hospital were randomly selected. The hospital formed an evaluation team that conducted preliminary evaluations of these prescriptions and an expert team that re-evaluated any problematic prescriptions. We analysed the irrational prescription rate, proportion of antibiotic use, and consistency between the evaluation and expert teams. At the end of the evaluation period, the utilisation rate of single antibiotics in the outpatient and emergency departments increased, the irrational prescription rate decreased, and the proportion of sold antibiotics gradually decreased. In addition, the consistency of prescription evaluation results between the evaluation and expert groups increased over time. In conclusion, monthly evaluation of antibiotic prescriptions is an effective management tool for the rational use of antibiotics in clinical practice and plays an important role in safe clinical drug use.
Sequential IVIM-Parametric as a Potential Image Biomarker in Evaluating the Radiosensitivity of Human Nasopharyngeal Carcinoma Xenografts
Authors: Xiao Youping , Chen Yunbin , Pan Jianji , Chen Ying , Zheng Xiang , Zheng Dechun , Guo Qiaojuan , Yao Yiqi
Published: November 2021

BACKGROUND AND PURPOSEIntravoxel incoherent motion (IVIM) is a considerable functional MR sequence in evaluated the tumor’s response to chemo-radiotherapy. Our aim was to investigate the sequential IVIM parametric in assessing the dynamic changes of histopathological features on nasopharyngeal carcinoma (NPC) xenografts after receiving the fractional radiations.EXPERIMENTAL APPROACH: Sixty BALB/c-nu nude mice were transplanted with NPC cell lines of CNE-1 and CNE-2 to raise xenografts which further received the fractional radiations. On 3.0T MR system, IVIM (14 b-factors: 0~1000 s/mm2) was performed on xegnorafts after radiations. IVIM-parametric of D, f and D* accompanied with the cellularity and necrosis proportion of NPC xenografts were calculated and analyzed respectively.KEY RESULTSNPC xenografts exhibited a larger D and necrosis proportion coupled with a smaller D*, f and cellularity after fractional radiations, and CNE-2 xenografts presented greater changes than CNE-1 xenografts (all P<0.01). Parametric D and f correlated negatively (r=-0.824, P<0.001) while D* correlated positively with f (r=0.758, P<0.001) and D (r=0.625, P=0.042). Moreover, D correlated negatively with cellularity (rs=-0.861, P<0.001) and positively with necrosis proportion (rs=0.952, P<0.001), f behaved a positive correlation with cellularity (rs=0.627, P<0.001) and negative with necrosis proportion (rs=-0.649, P<0.001). CONCLUSIONS AND IMPLICATIONS: Sequential parametric derived from IVIM are valuable in characterizing the dynamic changes in histopathological features of NPC xenografts and can be utilized as a potential image biomarker for non-invasive assessment of tumor’s radiosensitivity.
Systematic Review and Meta-analysis of Randomised Controlled Trials Testing the Effects of Proanthocyanidins Supplementation on Lipid Profile
Authors: Ren Jingyi , Sun Yiting , An Jiaqi , Chen Fengge , Yin Bowen , Zhang Fan , Zhang Limin , Ma Yuxia
Published: November 2021

Background: The studies that assessed proanthocyanidins (PCs) supplementation on lipid profile revealed contradictory results. The objective of this meta-analysis was to investigate the influence of PCs supplementation on lipid profile.Methods: Six databases (Pubmed, Web of Science, Cochrane Library, Scopus, EMBASE, and Google Scholar) were searched to identify for published relevant studies up to June 9, 2021. The weighted mean difference (WMD) and the corresponding standard deviations (SD) of the total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) were calculated to estimate the pooled effect. Results: A total of 1411 articles were identified through database searching, of which, seven studies were included in the meta-analysis. Pooled analysis suggested that PCs supplementation effectively affected the level of HDL-C (WMD: 2.716, 95% CI: 0.269, 5.163, p = 0.030), but had no significant effect on TC (WMD: -0.201, 95% CI: -6.443, 6.041, p=0.950), LDL-C (WMD: -3.000, 95% CI: -8.254, 2.254, p = 0.263), and TG (WMD: -8.874, 95% CI: -21.009, 3.260, p =0.152). In the subgroup analyses, a significant enhance in HDL-C in people with a shorter intervention duration (duration < 12 weeks) or people with a higher BMI (BMI ≥ 24 kg/m2). Conclusion: The present systematic review and meta-analysis suggest that PCs supplementation had no effects on TC, LDL-C or TG, whereas it may contribute to a change on HDL-C. Additional high-quality studies are needed to confirm this result.