bluuebunny/crossref_metadata_2025 huggingface dataset:
PERANCANGAN LOGO REGIONAL WORKSHOP WORLD OCEAN ASSESSMENT BELITUNG
Authors: Valentina Anny , Elysia Celine , Aurellia Meysia Dewi , Natassya Amelia
Published: November 2023

WOA 2022 is the second international agenda in Belitung Regency after the implementation of the G20 Development Working Group (DWG) in September. The World Ocean Assessment (WOA) is a world maritime meeting that focuses on discussing issues of the marine environment and their social and economic effects. Belitung was chosen because it has sea that still preserved from all kinds activities that can damage the conservation. Considering that the WOA event will be held in December 2022 and is an international event, to welcoming this event the local government needs help from professionals to design a logo event. As a very important visual identity, logo is the main face of a brand and has a meaning that can explain the vision or purpose of the brand. Implementing the method of this PKM, in the first stage communication was carried out with the Belitung Regency Regional Government. Through Deputy Regent Isyak Meirobie, the PKM DKV Untar team was invited to collaborate. The second stage is literature study, observation with visual design that supports the spirit of 'Let's Go Belitung'. Then find a solution to the problem by processing the icons from Belitung into a visualization that is manifested into a logo. In the fifth stage, a visual design is made by applying the Belitung icons to the logo and providing several visual alternatives and making revisions if necessary. In the end, a logo was sent which was then applied to Instagram @kemenkomarves.

WOA 2022 menjadi agenda internasional kedua di Kabupaten Belitung setelah pelaksanaan Development Working Group (DWG) G20 pada bulan September. World Ocean Assessment (WOA) adalah pertemuan maritim dunia yang berfokus membahas isu-isu lingkungan laut dan efeknya terhadap sosial dan ekonomi. Belitung dipilih karena memiliki laut yang masih terjaga kelestarian dari segala macam kegiatan lain yang dapat merusak pelestarian. Mengingat acara WOA akan dilaksanakan pada bulan Desember 2022 dan merupakan acara internasional, maka Pemda membutuhkan bantuan tenaga professional untuk merancang logo event untuk menyambut berlangsungnya event ini di Belitung. Sebagai identitas visual yang sangat penting, logo merupakan wajah utama dari sebuah brand dan tentunya memiliki makna yang dapat menjelaskan visi atau tujuan dari brand tersebut. Metode pelaksanaan PKM, pada tahap pertama dilakukan komunikasi dengan pihak Pemda Kabupaten Belitung. Melaui Wakil Bupati Isyak Meirobie diajaklah tim PKM DKV Untar untuk berkolaborasi. Tahap kedua studi pustaka, observasi dengan perancangan visual yang mendukung agar sesuai dengan spirit ‘Let’s Go Belitung”. Lalu mencari solusi dari permasalahan dengan mengolah ikon-ikon dari Belitung menjadi visualisasi yang diwujudkan menjadi logo. Pada tahap ke lima dibuat rancangan visual dengan mengaplikasikan ikon-ikon Belitung kedalam logo dan memberikan beberapa alternatif visual serta membuat revisi jika diperlukan. Pada akhir dikirimkan logo yang kemudia telah diaplikasikan pada Instagram @kemenkomarves.
PEMANFAATAN MEDIA SOSIAL INSTAGRAM DALAM MEMPROMOSIKAN BATIK TRIE
Authors: Stefanus Yordan Ponco , Utama Louis , Verawati
Published: November 2023

Batik is a part of the archipelago's original cultural works which is admired by audiences from all over the world and has a unique history. However, over time, batik is often identified with formal clothing that is old-fashioned, stiff, and only worn by parents in Indonesia by the current millennial generation. The rapid development of internet technology has given rise to social media which today, almost everyone uses as a medium for communicating, obtaining information, socializing and doing business, looking for entertainment and others. Social media creates changes in the way the world works, including the field of marketing, especially promotion and advertising, which results in the creation of online business trends. In order to reach consumers, observations, documentation, and literature studies are carried out to find out the most appropriate promotion concept according to marketing communication theory. Promotional activities carried out using Instagram have proven to be effective in attracting customers. The use of social media is expected to be able to market the products widely so that TRIE's business performance will increase.

Batik merupakan salah satu bagian dari karya budaya asli Nusantara yang dikagumi oleh khalayak dari berbagai penjuru dunia dan memiliki sejarah yang unik. Akan tetapi seiring berjalannya waktu, batik kerap kali diidentikkan dengan busana formal yang kuno, kaku, dan hanya dikenakan orang tua di Indonesia oleh generasi milenial pada saat ini. Perkembangan teknologi internet yang semakin pesat kian hari telah melahirkan media sosial yang saat ini, hampir semua orang menggunakannya sebagai media sebagai sarana dalam berkomunikasi, memperoleh informasi, bersosialisasi dan berbisnis, mencari hiburan dan lainnya. Media sosial menciptakan perubahan pada cara dunia bekerja, tak terkecuali bidang pemasaran khususnya promosi dan periklanan yang mengakibatkan terciptanya tren bisnis online. Guna menjangkau konsumen, dilakukan observasi, dokumentasi, dan studi kepustakaan untuk mengetahui konsep promosi yang paling tepat sesuai teori komunikasi pemasaran. Kegiatan promosi yang dilakukan dengan menggunakan media sosial Instagram terbukti efektif menarik pelanggan. Penggunaan media sosial diharapkan dapat memasarkan produk secara luas sehingga kinerja bisnis TRIE semakin meningkat.
EDUKASI PERPAJAKAN DAN PELATIHAN PENGHITUNGAN PAJAK PUSAT SISWA-SISWI SMAN 20 KAB.TANGERANG
Authors: Kurniawati Herni , Sari Vinetta Ratna , Lie Irene Kim
Published: November 2023

The direction of the Minister of Finance and the Minister of Education and Culture for the younger generation starting at the elementary, junior high and high school levels are already tax literate by creating a tax-aware and intelligent generation to understand the importance of the role of taxes in Indonesia as a source of state revenue apart from the oil and gas sector for the welfare of the people. PKM is intended to help Partners understand the science of taxation, which is part of Accounting Economics. In Indonesia, the central tax which is managed centrally by the Ministry of Finance through the DGT, consists of Income Tax, Value Added Tax, Land and Building Tax, Stamp Duty, and Sales Tax on Luxury Goods. PKM uses primary and secondary data, where primary data is obtained directly from Partners, such as data from interviews with school principals and teachers as well as data in the form of information to what extent students understand taxes. PKM utilizes secondary data from journal articles, internet news sources, and books to support PKM. The results of PKM PKM activities have been carried out on Friday 12 May 2023 at 10.00 WIB until finished, offline by visiting schools with students as part of PKM. The outputs of PKM activities are presentations in national seminars as speakers, and articles uploaded by PINTAR as additional output.
EVALUASI DISPLAY (TATA LETAK) PRODUK UNTUK MENINGKATKAN PENJUALAN PADA TOKO ONLINE LT-SHOP DI JAKARTA
Authors: Wijaya Andi , Jane Jennie , Budiman Bellinda
Published: November 2023

Every online store, both large and small, will face display (layout) problems. Setting the layout (display) for online store products is a problem that is often encountered and even unavoidable, even if it is in a smaller or simpler scope. If the display settings are properly planned, it will affect the efficiency and sales of online stores. The main goal to be achieved in display planning (layout) at the LT Shop online store is basically to facilitate the search for products that meet consumer desires which in turn can increase sales. This PKM program is in the form of determining the display (layout) for the LT Shop online store. So far, the displays in the online store are less attractive and still disorganized. With the correct display (layout), it will facilitate the process of searching for goods and can create increased transactions. Tarumanagara University as an entrepreneur campus that helps provide funds for the implementation of this community service activity.

Setiap toko online baik toko dalam skala besar maupun kecil akan menghadapi permasalahan display (tata letak). Pengaturan tata letak (display) untuk produk toko online merupakan masalah yang sering dijumpai bahkan tidak dapat dihindari,  meskipun dalam lingkup yang lebih kecil atau sederhana. Apabila pengaturan display ini terencana secara baik akan berpengaruh terhadap efisiensi dan penjualan toko online. Tujuan utama yang ingin dicapai dalam perencanaan display (tata letak) pada toko online LT Shop pada dasarnya adalah untuk memudahkan pencarian produk yang memenuhi keinginan konsumen yang pada akhirnya dapat meningkatkan penjualan. Program PKM ini berupa penentuan display (tata letak) pada toko online LT Shop. Selama ini display yang ada di toko online tersebut kurang menarik dan masih belum teratur. Dengan display (tata letak) yang benar maka memudahkan proses pencarian barang dan dapat menciptakan peningkatan transaksi. Universitas Tarumanagara sebagai kampus entrepreneur yang membantu penyediaan dana demi terselenggaranya kegiatan pengabdian masyarakat ini.
PELATIHAN MODUL PEMBELIAN SOFTWARE ACCURATE BAGI SISWA SMA TARSISIUS I
Authors: Sriwati Sriwati , Laksa Kirana Alika , Cahyani Putri Cilvia , Safira Intan
Published: November 2023

Banyak perusahaan yang telah memanfaatkan teknologi informasi untuk menjalankan kegiatan bisnisnya. Hal ini tentunya akan berdampak pula pada pencatatan akuntansi dan penyusunan laporan keuangan perusahaan. Namun, pelajaran akuntansi yang diberikan pada sekolah menengah atas (SMA), salah satunya SMA Tarsisius I, hanya berfokus pada pencatatan akuntansi dan penyusunan laporan keuangan secara manual. Dengan demikian, murid SMA saat ini memerlukan tambahan pengetahuan mengenai bagaimana cara pengoperasian software akuntansi. Di Indonesia, Accurate merupakan salah satu software akuntansi yang banyak digunakan, terutama oleh perusahaan kecil dan menengah yang merupakan target pasar dari software Accurate. Oleh karena keterbatasan waktu, maka pelatihan ini hanya membahas mengenai pengoperasian modul pembelian menggunakan software Accurate. Mitra dari kegiatan ini adalah SMA Tarsisius I. Peserta pelatihan ini merupakan siswa kelas X, kelas XI, dan kelas XII yang tergabung dalam ekstrakurikuler akuntansi. Pelatihan dilaksanakan dengan cara memberikan pemaparan materi, kemudian dilanjutkan dengan tanya-jawab, dan diakhiri dengan kuis. Materi pelatihan ini membahas mengenai cara menginput permintaan pembelian, pesanan pembelian, penerimaan barang, faktur pembelian, retur pembelian, dan pelunasan pembelian serta cara menampilkan laporan-laporan yang terkait dengan transaksi pembelian. Kegiatan ini telah terlaksana dengan baik pada bulan Januari 2023 di SMA Tarsisius I. Setelah mengikuti pelatihan ini dan dari hasil kuis yang telah dilaksanakan, dapat disimpulkan bahwa peserta pelatihan dapat mengoperasikan modul pembelian software Accurate secara mandiri. Oleh sebab itu, diharapkan agar pelatihan ini dapat terus dilakukan dimasa yang akan datang.
PENGUKURAN KADAR GULA DARAH DAN PENYULUHAN PENGATURAN KADAR GULA DARAH DI PEJAGALAN JAKARTA BARAT
Authors: Susy Olivia Lontoh  , Nanang Wahyudi  , Dondie  , Naufal Ikbar
Published: November 2023

Pemeriksaan kadar gula merupakan tindakan preventif yang penting dalam pengawasan gula darah. Diabetes melitus adalah penyakit metabolik kronis perlu segera terdeteksi.  Upaya deteksi dini terkait diabetes melitus maka tim pengabdian masyarakat   FK UNTAR  melakukan pemeriksaan kadar gula darah serta edukasi tentang pentingnya pengaturan kadar gula darah.  Tingkat aktivitas fisik yang rendah dan obesitas pada dewasa muda menjadi  tantangan utama di bidang kesehatan masyarakat di Indonesia. Kegiatan pemeriksaan kadar gula darah  serta edukasi kesehatan  telah dilakukan pada hari Jumat, tanggal 11 Mei 2023 pukul 13.00-16.00 di Pejagalan Jakarta Barat. Mitra kegiatan  sejumlah 21 orang dengan kriteria  dewasa muda berusia 20-65 tahun dan dikeluarga terdapat riwayat darah tinggi serta diabetes melitus. Kegiatan pemeriksaan kadar gula darah disertai pengukuran tekanan darah, berat badan dan tinggi badan. Usia peserta pengukuran kadar gula darah dan penyuluhan berkisar 40-68 tahun.  Hasil pemeriksaan  kadar gula darah sewaktu berkisar 108-468 mg/dl.  Peserta dengan kadar gula darah sewaktu normal yaitu 17 (81%) peserta dan tinggi  sebesar 4 (9%) peserta.  Peserta yang tekanan darah  normal  1 (4,8 %) peserta,  pre hipertensi 5 peserta  (23,8%)  dan hipertensi  15 peserta (71,4 %).
Variable Clustered Fuzzy Rules for Self-Tuning Scheme for Respiratory Distresses by Similarity and the Phase Plane Trajectory Concept
Authors: Naskar Indrajit
Published: November 2023

This work proposes a fuzzy rule extraction methodology for a self-tuning fuzzy controller based on the fuzzy clustering method (FCM) and the similarity approach technique. The similarity technique and phase plane trajectory method are used to even lower the acquired rules. To show a potential rule extraction scheme, the self-tuning fuzzy-logic-based proportional-derivative (STFLPDC) with 49 expert fuzzy rules and 49 clustered fuzzy gain rules is used. The utility of the approach is validated using common clustering validity indices. With 49 initial clustered fuzzy rules, the suggested method addressed oxygen supply in a human respiratory model. After further reduction using the similarity strategy, 29 and 14 fuzzy rules remained. Parallel to this, a real-time benchmark application using 49, 21, and 16 extracted fuzzy gain rules is used to access the performance of a lab-based overhead crane. Finally, to investigate control performance in both models, the phase plane trajectory concept is used to generate as few as 13 fuzzy gain rules.
Blue Jacket Blues: Lost Recordings of Johnny Cash at the Naval War College – Live in ’75
Authors: Kohnen David , Cash, Jr. Roy
Published: November 2023

Sailors far from home often identified with the lyrics of traditional sea shanties, which highlighted the isolation and hard work on an unforgiving sea. Following in this tradition, American sailors also gravitated to the punchy diddy bopper rhythms and bleak lyrical storyline of Cash’s rockabilly classic, “Folsom Prison Blues” Since he scored that first hit in 1955, Cash has cast a very long shadow on American popular culture. Given all that has been written and generally remembered about Cash, many surprises remain unexplored in the remarkable chronology of his life and rise in popular American music. One such example is the previously undocumented performance by the “Man in Black” on St. Patrick’s Day in 1975 at the Naval War College in Newport, Rhode Island. Using recently rediscovered audio from the event, this article examines the concert, as well as the broader influence of Cash upon popular culture, the role of military service upon his work, his intimate connection with the Naval War College, and his broader impact on the United States military.

Les marins loin de chez eux s’identifiaient souvent aux paroles des chants de marins traditionnels qui traitaient de l’isolement et du travail acharné sur la mer impitoyable. Reprenant cette tradition, les marins américains étaient également attirés vers les rythmes percutants et le sombre récit du classique du rockabilly de Johnny Cash intitulé «Folsom Prison Blues.» Après avoir connu ce premier succès en 1955, Cash a marqué à tout jamais la culture populaire américaine. Malgré tout ce qui a été écrit et tout ce que nous retenons de Cash, bon nombre de sujets demeurent peu connus dans la chronologie remarquable de sa vie et son grand rôle dans la musique populaire américaine. On peut citer, à titre d’exemple, le spectacle non déjà documenté du chanteur connu sous le nom de « Man in Black » le jour de la St-Patrick en 1975 au Naval War College à Newport, au Rhode Island. À l’aide de l’enregistrement sonore du spectacle qu’on vient de redécouvrir, cet article étudie le spectacle ainsi que l’influence de Johnny Cash sur la culture populaire, le rôle du service militaire sur son œuvre, son lien intime avec le Naval War College et ses répercussions plus vastes sur l’armée américaine.
Outcomes of Editorial Intervention in Texts from National Library of Wales, Brogyntyn MS ii.1: Past, Present and Futur
Authors:   University of Huelva (Spain), Carrillo-Linares María José
Published: November 2023

In editing medieval manuscripts changes in tastes, needs, conventions and resources have resulted in edited texts so disparate that it is difficult to visualise the relative uniformity exhibited by a codex copyist. In this article I compare different editions of texts copied by one of the scribes of National Library of Wales, Brogyntyn MS ii.1, responsible for twenty-one entries in the manuscript. Each edition has been collated with the manuscript to establish the criteria adopted by each editor in their transcriptions. I focus on how editors address aspects such as expansion of abbreviations, normalisation and treatment of certain palaeographical peculiarities. The goal is to show how the work of the same scribe has been variously interpreted and how this variation disguises the essence of this copyist’s written language.
Guy de Chauliac’s On Bloodletting in Glasgow, University Library, MS Hunter 307 (ff. 165v-166v
Authors:   University of Málaga (Spain), Esteban-Segura Laura , Soriano-Jiménez Carlos ,   University of Málaga (Spain)
Published: November 2023

This paper presents the edition and analysis of the text housed in Glasgow, University Library, MS Hunter 307, ff. 165v-166v, which contains a version of the treatise On Bloodletting by Guy de Chauliac, an important author of medieval surgery, and which remains unedited, to the best of our knowledge. The objectives are the following: first, to investigate the transmission of the text; second, to explore the main codicological and palaeographical features of the treatise; third, to provide the first edition of the witness and discuss its main tenets; and finally, to examine the language of the text in order to locate it geographically. The assessment of all of the above will offer a complete picture of the treatise and will help to place it in its material and cultural context.
Academician Ivan S. Kolesnikov — Military surgeon, Scientist, Teacher
Authors: Kotiv B. N. , Dzidzava I. I. , Iontsev V. I. , Barinov O. V. , Dmitrochenko I. V.
Published: November 2023

Ivan Stepanovich Kolesnikov (1901–1985) – an outstanding Soviet surgeon, Doctor of Medical Sciences, Professor, Academician of the USSR Academy of Medical Sciences, Major-General of Medical Service (1953), Honored Scientist of RSFSR (1964), Hero of Socialist Labor (1976), Lenin Prize Laureate (1961) and USSR State Prize Laureate USSR (1985). Ivan S. Kolesnikov had a glittering life from a junior medical staff to an academician. He participated in 6 wars. Academician Kolesnikov was a talented organizer. He supported and developed thoracic and cardiovascular surgery, anesthesiology-resuscitation, combustiology, transfusiology. His monographs have become handbooks for surgeons in our country: “Resection of the lungs: indications, surgical techniques, postoperative care” (1960), “Organ-sparing resections of the lungs in tuberculosis” (1965), “Autotransfusion of blood and its components in surgery” (1979). Ten volumes of the “Atlas of Gunshot Wounds” prepared by him and his collaborator Academician P. A. Kupriyanov were published in 1946–1955.
HORMONEMA MACROSPORUM AS A PROMISING MELANIN PRODUCER
Authors:   Favorsky Irkutsk Institute of Chemistry SB RAS, Timokhin K.M. , Starchenko I.V. , Belovezhets L.A.
Published: November 2023

Melanins are a class of polyfunctional compounds that may be a solution to the problem of human adaptive resources. In this work, we investigated the potential of the microorganism Hormonema macrosporum as a promising melanin producer. The optimal conditions for cultivation of the microorganism were selected. The best was cultivation on liquid glucose-collagen medium and solid mash-agar. The pigment yield amounted to 30,23 %.
LEVEL OF ANTIMICROBIAL ACTIVITY DETERMINATION USING MFC
Authors:   Belarusian State University, Minsk, Trushlis E.V. , Novosadskaya A.E. , Lazukin A.A. ,   Tyumen State University,   ITMO University, Saint Petersburg
Published: November 2023

A method for determining the level of antimicrobial activity using microbial fuel cell (MFC) has been developed. It has been shown that MFC can be used as a biosensor, which makes it possible to develop new express methods for determining antimicrobial activity for various agents.
RAPID IMMUNOCHEMICAL METHODS FOR THE DETECTION OF ORTHOPOXVIRUSES
Authors:   State Research Center of Virology and Biotechnology VECTOR, Koltsovo, Ushkalenko N.D. , Ersh A.V. , Filatov P.V. , Poltavchenko A.G.
Published: November 2023

The aim of work is to develop rapid and sensitive methods for the immunochemical detection of poxviruses. The methods are based on one-step dot-analysis using protein arrays and ELISA. Studies were performed on viral cultures and clinical samples from rabbits and mice. The sensitivity range for detecting viral material in the dot-analysis is 103 –104 PFU/ml, ELISA 102 –103 PFU/ml, and for clinical samples 104 PFU/ml both methods showed.
EFFECT OF ETHANOL EXTRACT OF MONARDA CITRIODORA (CERV. EX LAG.) ON THE REPRODUCTIVE SYSTEM OF DROSOPHILA MELANOGASTER
Authors:   Ural Federal University named after the First President of Russia B.N. Yeltsin, Ekaterinburg, Chernaia A.I. , Antosyuk O.N. , Bolotnik E.V. ,   Botanical Garden UB RAS, Ekaterinburg
Published: November 2023

During testing of the Monarda citriodora extract on the example of a model object Drosophila melanogaster, its effect on the reproductive system was found, namely, a positive effect on sexual activity and a negative effect on average individual fertility and an alteration in regulated cell death in the ovaries of females.
NEW COLLOIDAL SYSTEMS BASED ON BIOMIMETIC POLYCOMPLEXES
Authors:   Institute of Radio-engineering and Electronics RAS, Moscow, Grigoryan I.V. , Spiridonov V.V. , Adelyanov A.M. , Koksharov Y.A. , Potapenkov K.V. , Taranov I.V. , Khomutov G.B. , Yaroslavov A.A. ,   Lomonosov Moscow State University
Published: November 2023

In the article, new colloidal systems are obtained and studied, which have prospects for use as carriers of medicinal compounds. The colloidal systems under consideration are polymer complexes based on polyacrylic acid of various molecular weights and biogenic polyamine with magnetic iron oxide nanoparticles. The magnetic properties of polycomplexes with included magnetic iron oxide nanoparticles have been studied.
STRUCTURAL PECULIARITIES OF THE FOF1 -ATP SYNTHASE PROTON HALF-CHANNELS IN MEMBRANES WITH DIFFERENT LIPID COMPOSITIONS
Authors:   Institute of Cytochemistry and Molecular Pharmacology, Moscow, Ivontsin L.A. , Mashkovtseva E.V. , Nartsissov Y.R. ,   Pirogov Russian National Research Medical University, Moscow,   Biomedical Research Group, BiDiPharma GmbH, Siek, Germany
Published: November 2023

Molecular dynamics simulations were used to study the membrane lipid composition influence on the proton half-channels structure of Fo F1 -ATP synthase. A possible network of polar amino acid residues and water molecules, which have a significant effect on proton transport, were described. The effect of cardiolipins on the structural dynamics of amino acid side chains and protein hydration was evaluated.
THE STUDY OF THE SURVIVAL OF HUMAN MICROBIOME INTESTINAL BACTERIA AFTER CRYOPRESERVATION IN LIQUID NITROGEN
Authors:   Institute of Cell Biophysics RAS, Pushchino, Zalomova L.V. , Fesenko Jr. E.E.
Published: November 2023

A concept on gut microbiota as one of the key players in maintaining the human health is becoming more and more actual [1, 2]. Currently two main strategies can be distinguished in gut microbiota valuable biological matter application in the therapy of various pathologies, transplantation and application of probiotic medications, which both are focused on restoration of balance of microorganisms. In this regard, development of new methods for long-term conservation of microbiota providing high conservation degree of species and quantitative composition and quantitative parity of the bacteria forming the microbiocenosis is more and more relevant.
An Assessment of Cardiac Dysfunction in Cancer Patient Receiving Chemotherapy: A Hospital-Based Non-Invasive Study
Authors: Ranjan Subhash , Shukla Ashish Kumar , Gupta Prabhakar , Yegade Walmik Shrihari , Saha Debanjan
Published: November 2023

Objectives:

To assess cardiac dysfunction in cancer patients receiving anthracycline based chemotherapy and to detect cardiac dysfunction in the initial stage.

Materials and Methods:

An open labelled prospective single site study of assessment of cardiac dysfunction in patient receiving chemotherapy.

Results:

Post chemotherapy, more number of patients had evidence of cardiac dysfunction on the basis of history and physical examination but statistically significant association was found only in fatigability, pallor, oedema and rales. Among the users or Doxorubicin and Epirubucin based chemotherapy, cardiac dysfunction was observed in 19.56% (n = 9) and 4.3% (n = 2) respectively. Among those on Doxorubicin, in the cumulative dose range of 510-600 mg, two patients (20%) had clinical cardiac dysfunction and one patient (10%) had subclinical cardiac dysfunction.

Conclusion:

Cardiac dysfunction is one of the dreaded complications of chemotherapy agent anthracycline. It adds to the co morbidity of cancer. Small increase in the risk of common and serious adverse health events, such as cardiac disease, has important public health implications. Effective steps have taken at proper time; can prevent the onset or exacerbation of these complications.
RISK STRATIFICATION OF ATRIAL FIBRILLATION PROGRESSION
Authors:   Grodno State Medical University, Grodno, Belarus, Snezhitskiy V. A. , Bukvalnaya N. V. ,   Grodno State Medical University, Grodno, Belarus, Yakubova L. V. ,   Grodno State Medical University, Grodno, Belarus
Published: November 2023

Paroxysmal atrial fibrillation can progress over time to stable forms, which is associated with an increased risk of adverse events and outcomes. The use of prediction tools for arrhythmia progression may be useful in identifying highrisk patients. The review considers eight scales for stratifying the risk of atrial fibrillation progression, alongside with their comparative analysis. The main risk factors for arrhythmia recurrence and its transition to a permanent form are described. The obtained results show that these scales are characterized by the heterogeneity of the assessed variables, which dictates the need to create new diagnostic tools.
THE ROLE OF OZONE IN ADAPTIVE CHANGES IN THE ERYTHROCYTE LINK
Authors:   Grodno State Medical University, Grodno, Belarus, Biletskaya E. S. , Zinchuk V. V. ,   Grodno State Medical University, Grodno, Belarus
Published: November 2023

The analysis of literature and our own data on the study of the mechanisms of the physiological action of ozone on the erythrocyte link of the blood was carried out. The present article discusses the effect of ozone on the oxygenbinding capacity of blood and its pro-oxidant-antioxidant balance. The effect of this gas manifests itself in different ways under conditions of changing activity of the system of gas transmitters (nitrogen monoxide and hydrogen sulfide) and at different values of the partial pressure of oxygen and carbon dioxide. The antihypoxic effect of ozone is provided with the participation of gas transmitters that realize their action through intraerythrocytic mechanisms of formation of hemoglobin affinity for oxygen, which justifies its use as a means of improving the adaptive and antihypoxic capabilities of the body.
GENERAL PRINCIPLES OF BACTERIAL COMMUNICATION
Authors:   Gomel State Medical University, Gomel, Belarus, Artsiukh T. V. ,   Grodno State Medical University, Grodno, Belarus, Sidorovich E. A. ,   Grodno State Medical University, Grodno, Belarus, Tapalskiy D. V. ,   Gomel State Medical University, Gomel, Belarus
Published: November 2023

This article presents up-to-date information on the phenomenon of intercellular communication in bacteria, its role in the expression of virulence genes and, in particular, in the spread of antibiotic resistance. The basic principles of quorum functioning inherent in all currently known bacterial communication systems are highlighted. The main signaling molecules (autoinducers) of intraspecies, interspecies, epinephrine and peptide communication have been analyzed. The role of blocking information communication (signaling molecules) between bacteria as an alternative to the discovery of new antibiotics against bacteria with extreme and complete antibiotic resistance have been evaluated. Key words: quorum sensing, signaling molecules, receptors, gene expression, quorum suppression.
Potenziale der Digitalisierung für mittelständische Unternehmen erkennen und nutzen
Authors: Franke Patrick
Published: November 2023

Big Data und das Internet der Dinge (IoT) gelten als Antrieb der Digitalisierung. Industrie 4.0 sorgt dabei für eine gänzlich neue Wettbewerbssituation, in der Daten maßgeblich über den Unternehmenserfolg entscheiden. Mittlerweile gilt die datengetriebene Optimierung von Geschäftsprozessen im eigenen Unternehmen nur als Etappenziel. Um das volle Potenzial der Digitalisierung auszuschöpfen, müssen völlig neue Geschäftsmodelle entwickelt werden, damit die komplette Wertschöpfungskette vom Lieferanten bis zum Endkunden von den Daten profitieren kann.

 

Lange Zeit waren nur große Konzerne in der Lage von Big Data zu profitieren. Das hat sich durch immer preiswertere Sensoren, Clouddienste und IoT-Software ohne hohen Programmieraufwand drastisch geändert. Nun können auch mittelständische Unternehmen die digitale Transformation nutzen. Entscheidend für die erfolgreiche Einführung sind skalierbare Lösungen, eine konfigurierbare Umgebung sowie ein Wandel der Infrastruktur. Meist existiert bereits ein CRM-System für Vertrieb und Marketing, während auch Produktion und Service teilweise digitalisiert sind. Die Herausforderung besteht nun darin, IoT-Lösungen und Big Data zu erweitern und Unternehmensbereiche sinnvoll miteinander zu verknüpfen, damit die Potenziale der Digitalisierung für jeden spürbar werden.
Anwendbarkeit von Process Mining Methoden zur kontinuierlichen Verbesserung von IT Service Management Prozessen nach ITIL
Authors: Angelova Elena
Published: November 2023

Bei der steigenden Wettbewerbsdynamik müssen die Unternehmen heutzutage ihre Geschäftsprozesse kontinuierlich verbessern und überwachen, um konkurrenzfähig zu bleiben. In diesem Zusammenhang werden die Rolle von Business Process Management und Methoden zur Verbesserung von Prozess- Qualität und -Effizienz wie ITIL und COBIT immer wichtiger. Außer an den Referenzmodellen ist das Interesse von Unternehmen an neuen Technologien für Datenanalyse und Informationsgewinn gestiegen. Eines dieser Werkzeuge ist Process Mining, bekannt auch als Workflow Mining. Mit Process Mining können Wissen von Prozesslogdaten zur Prozessüberwachung und -kontrolle gewonnen werden. In diesem Artikel wird die Anwendbarkeit von Process Mining Methoden für die kontinuierliche Prozessver-besserung analysiert. Der Fokus ist auf IT Service Ma-nagement Prozesse nach ITIL Best Practice gelegt.
Biomimetic Superhydrophobic Laser-Induced Graphene Surface for Desalination and Brine Treatment with Excellent Salt Resistance
Authors: C.L Aiswarya , P. Singh Swatantra
Published: November 2023

The brine produced during desalination has emerged as a significant concern due to its challenge in management. Therefore, there arises a need for advanced brine treatment processes that operate with a lower energy footprint. Solar interfacial evaporation has promising abilities to treat brine at less cost and lower energy consumption. However, the intensity variation of sunlight and clogging of the interfacial surface with salt over time has impacted evaporation performance. Therefore, the present research focuses on developing joule-heated and solar-heated Laser-Induced Graphene (LIG) interfacial evaporating surfaces for continuous brine treatment. Here is the first time a dual-sided superhydrophobic LIG surface is employed for brine treatment. The surfaces are designed to improve salt rejection capabilities through a water-repellent feature. PES-LIG undergoes surface post-modification in the fabrication pathway, while the other side acquires superhydrophobic properties via direct engraving of the PVDF-AR 972 layer. The evaporation performance is tested with distilled water and NaCl solutions with concentrations of 3.5%, 12.5%, 17.5%, and 24%. The dual-stacked configuration with coupled solar (one sun) - joule heating (5 V) attained an evaporation rate of ~5 kgm-2h-1 for D.I water and ~ 2.5 kgm-2h-1 for 24 wt% NaCl solution. The improved performance resulted from an increase in surface temperature from the bottom side, and hydrophobic modifications that induced backward diffusion preventing salt from reaching the surface. These engineered self-cleaning surfaces can be placed adjacent to desalination plants and easily coupled with renewable energy sources to ensure continuous operation. These systems can function during nighttime without requiring complex machinery and can operate with a lower special footprint as well as energy footprint.
PhAI: A deep learning approach to solve the crystallographic phase problem
Authors: Madsen Anders Østergaard , Larsen Anders Støttrup , Rekis Toms
Published: November 2023

For more than 100 years, X-ray crystallography has provided a unique view on the three-dimensional structure of atoms and molecules in crystals. However, to determine even the simplest structures now and a hundred years ago, one needs to overcome a mathematical hurdle for which the solution is not known even to this day. To reconstruct the 3-dimensional electron density map, from which the structure can be inferred, the complex structure factors F = |F| exp(iφ) of a sufficiently large number of diffracted reflections must be known. In a conventional diffraction experiment, only the amplitudes |F| are obtained, while the phases φ are lost. This is the crystallographic phase problem. Seventy years of research has established successful ab initio phasing methods such as direct methods and charge flipping. However, these methods are limited to atomic- resolution data, complicating structure determination from weakly-scattering crystals. Here, we show that a neural network can solve the crystallographic phase problem at a resolution of only 2 Å. We have developed an approach to generate millions of artificial structures and respective diffraction data for training of a neural network. We demonstrate that ab initio phasing based on this neural network is possible using 10 % to 20 % of the data needed for present-day methods, breaking the paradigm that atomic resolution is necessary for ab initio structure solution. The current neural network works in common centrosymmetric space groups and for modest unit cell dimensions, and suggests that neural networks can be used to solve the phase problem in the general case. This approach will enable structure solution for weakly-scattering crystals such as metal-organic frameworks or nanometer-sized crystals investigated using electron diffraction.
Deep Learning Strategies for Enhanced Molecular Docking and Virtual Screening
Authors: Müller Pereira da Silva Matheus , Alvim Guedes Isabella , Lima Custódio Fábio , Krempser Eduardo , Emmanuel Dardenne Laurent
Published: November 2023

Over the last few years, machine learning (ML) and deep learning (DL) have been revolutionising the computer-aided drug discovery landscape. With the recent availability of the so-called ultra-large virtual libraries (libraries with up to billions of readily available virtual compounds), new ML and DL approaches have been developed to enable the exploration of these large chemical spaces, achieving promising results. Molecular docking is one of the most widely used computational methods for performing in silico screenings of virtual libraries. The two primary goals of molecular docking are to predict the correct binding pose of small molecules inside the binding pocket of a protein target and also estimate the binding affinity of the protein-ligand complex. In particular, DL methods have been applied in all aspects of protein-ligand molecular docking, from pose and binding affinity prediction to virtual screening campaigns, improving computational costs and accuracy. This chapter introduces the core aspects of the molecular docking methodology and some fundamental concepts of machine learning and deep learning. We also describe different types of molecular representations and DL architectures commonly employed in the field, such as convolutional and graph neural networks. Furthermore, we provide insights into potential applications by presenting related works from the scientific literature. Finally, we discuss the current limitations, challenges, and biases of DL applied to molecular docking.
Parody as the “epicenter” of carnivalization
Authors: Samokhina Viktoriia , Tarasova Svitlana
Published: November 2023

Carnivalization is the embodiment of direct connection with real life which allows us to establish the essence of the phenomenon of “permanent dialogic carnival” and to define the boundaries in disclosure of its nature. In this article we consider the genre of parody, the main participant of which is the discursive personality of the parodist. The aim is comprehensive multifaceted study and description of modern parody in polyphony of its forms. In parody, which heads the system of conversational carnivalized genres, where the addressee parodist acts as a communicative type of discursive personality, it was established the existence of a paradox of parody – the logic of alogism. This has become the scientific novelty of the study. Alogism is a surprise, a scandal, a game with the addressee. The logic of alogism in its basis implies ambiguity. Communicative features of the parody genre are established (intentionality, intentional explicit realization of comic means). Three types of parody are established in a dialogical relationship: 1) parody as a speech genre; 2) parody of the language; 3) parody as an element of the text. Two types of parody are analyzed: 1) parody of form / mocking imitation, 2) imitation and parody of content. Both types are based on hyperbole, grotesque, when either the situation itself, or the language of the characters, or the characters themselves are exaggerated and, moreover, significantly modified. A special characteristics of the parody genre is its interdiscursiveness. Parody performance is solely related to the act of evaluation and interpretation. The linguistic aspect of parody is related to the dialogue of the carnival world, which requires the parodist to expressive ideas, images, jokes, style and words; it is characterized by intensification of expression, emotional and artistic coloring. The perspective of the research is the contrastive study of parody as a linguocognitive phenomenon determined by cultural-historical context.
Experimental study of the impact of using machine translation engines on the quality of translation of texts in the field of Jungian psychology
Authors: Olkhovska Alla , Chystiakova Alina
Published: November 2023

The article is devoted to the study of the impact of using machine translation engines (Microsoft Translator and DeepL Translate) on the quality of translation of texts in the field of Jungian psychology. The translation quality was determined by the number of errors and quality of rendering psychological terminology. The modern translation market offers many online engines designed to help with the translation of psychological texts, which gradually get more recognition, but it’s important to define the most efficient machine translation engine that can be recommended for working with the texts in the field of Jungian psychology. In the course of conducting our research, we formulated a research hypothesis, selected a psychological text rich in psychological terminology, compiled a bilingual glossary based on the selected text, selected machine translation engines and the procedure of evaluating errors, analyzed translated texts in terms of general quality and in terms of transferring psychological terminology, processed the experimental data and represented the results in the form of tables providing an expert assessment of the empirical data and formulated conclusions. In the process of conducting the experiment, the second hypothesis was confirmed: the quality of conveying the content and basic psychological terminology in the translation of the text in the field of Jungian psychology turned out to be higher when using the DeepL Translate machine translation engine, and therefore it is this machine translation engine that we can recommend for the use by professional translators working with texts in the field of Jungian psychology. However, when using this online translator, one needs to be aware of the inaccuracies, literalism tendency and stylistic errors that the machine makes.
Ideological and Political Integration Strategies in Interior Design Professional Courses Under the Background of Innovation and Entrepreneurship
Authors: She Linzi
Published: November 2023

Based on the ideological and political requirements of interior design professional courses, exploring the integrated education path of professional plus innovation and entrepreneurship requires first expanding the ideological and political content of professional introductory courses, core courses, and expanded courses. Then, we will reshape the curriculum system based on the principle of connecting professional teaching and ideological and political courses, focusing on the realistic principle of talent needs, striving for student growth, adjusting the course content, optimizing the teaching model, and transforming teaching through in- and out-of-class practice and counterpoint guidance.
Research on the Teaching Reform and Practice of the Food Analysis Course Under the New Situation
Authors: Tang ZhongSheng , Chen Jin , Zhu Siming , Hua Yanglin , Zeng Di
Published: November 2023

With the development of society, the overall development of various industries in our country is unprecedentedly prosperous. However, various damaging industries with the sole goal of profit have emerged, significantly reducing people’s experience in basic needs such as food, clothing, housing, and transportation. Food analysis course is an essential primary subject established by colleges and universities to cultivate food quality and safety talents. In order to further ensure the food safety of society, this article mainly analyzes the teaching reform path of food analysis courses under the new situation. We hope the views in this article can provide guidelines for relevant workers.
Reform Strategies for Higher Education Management in Collaborative Education
Authors: Fu Xing , Padolina Layla P.
Published: November 2023

Collaborative education focuses on cross-department and cross-level cooperation to create a multi-dimensional student growth environment. This article mainly explores the significance of higher education management in the context of collaborative education, analyzes existing problems in higher education management, and proposes reform strategies for higher education management in the context of collaborative education, including resource integration, transformation of educational concepts, strengthening of process management, and improvement of relevant laws and policies. These are expected to provide practical guidance and suggestions for modern university education management.
Development of the Methodology for Determining the Indicators of Efficiency and Effectiveness of Higher Education
Authors:   Financial University, Moscow,  Russia, Kamolov S.G.
Published: November 2023

The subject of the research is conceptual and methodological approaches to determining key performance indicators for higher education institutions focused on research and technological entrepreneurship. The purpose of the work is to clarify the methodology for evaluating the effectiveness of R&D in higher education, taking into account the features of science as an environmental economic system and long—term goals of public administration. The study revealed that key performance indicators of science and higher education are often set arbitrarily and, as a result, reflect the results of organizations' activities biased. Criteria for the selection of indicators of the effectiveness of science and higher education are proposed: connection with the strategy of the state or enterprise; consideration of "environmental" and corresponding indicators. It is concluded that the methodological approach to evaluating the results of research in higher education is determined by the type of economic system of the country and the presence of a competitive environment. Proposals have been formulated to finalize the targets of the national project "Science and Universities". The practical significance of the research lies in the possibility of its use by public authorities for the selection of target indicators of projects and programs of higher educational institutions of research orientation.
Distribution of beta-casein genotype in two generations in cows of the Kholmogory breed
Authors: Khudyakova Natalia Aleksandrovna , Tulinova Olga Vasilievna , Kozhevnikova Irina Sergeevna , Kudrina Marina Aleksandrovna , Kondakova Alyona Andreevna
Published: November 2023

One of the most effective ways to produce A2 milk is marker selection using the results of animal genotyping according to beta-casein genotypes, since A2 milk is produced only by cows with the A2A2 genotype. In this study, the inheritance of the beta-casein gene genotype in two generations of cows of the Kholmogory breed in "Agrofirma "Kholmogorskaya" and "Kholmogorskiy plemzavod", Arkhangelsk region was studied. The A1 and A2 alleles of the beta-casein gene were determined by an allele-specific PCR method. As a result of the study, it was found out that the frequency of the A1 and A2 alleles of the beta-casein gene in daughter offspring and mother cows practically did not change in one generation (A1 allele from 53 to 54 % and A2 allele from 46 % to 47 %; A1 allele from 68 to 61 % and A2 allele from 32 to 39 %). This fact indicates the absence of breeding pressure. Since the task of modern animal husbandry is to create herds of the Kholmogory breed with the A2A2 genotype for the production of high-quality milk, then for further breeding, attention should be paid to animals with the A1A2 and A2A2 genotypes. Having modeled the selection in herds, that is, excluding mothers with the A1A1 genotype from reproduction, and calculating the distribution of genotypes of descendants in the remaining part of the maternal stock of both herds, it was found that the proportion of descendants with the A1A1 genotype decreases in farms, the relative number of heterozygous daughters in the breeding farm increased by 5.0 %, and in the agrofirm decreased by 6.3 %, but at the same time, the number of A2A2 daughters increased by 6.7 and 4.0 %, respectively.