bluuebunny/crossref_metadata_2025 huggingface dataset:
Minimally invasive Ivor-Lewis esophagectomy for esophageal cancer
Authors: Eroğlu Atilla , Daharlı Coşkun , Bilal Ulaş Ali , Keskin Hilmi , Aydın Yener
Published: August 2022

Background: In this study, we present our minimally invasive Ivor-Lewis esophagectomy technique and survival rates of this technique.

Methods: Between September 2013 and December 2020, a total of 140 patients (56 males, 84 females; mean age: 55.5±10.3 years; range, 32 to 76 years) who underwent minimally invasive Ivor- Lewis esophagectomy for esophageal cancer were retrospectively analyzed. Preoperative patient data, oncological and surgical outcomes, pathological results, and complications were recorded.

Results: Primary diagnosis was esophageal cancer in all cases. Minimally invasive Ivor-Lewis esophagectomy was carried out in all of the cases included in the study. Neoadjuvant chemoradiotherapy was administrated in 97 (69.3%) of the cases. The mean duration of surgery was 261.7±30.6 (range, 195 to 330) min. The mean amount of intraoperative blood loss was 115.1±190.7 (range, 10 to 800) mL. In 60 (42.9%) of the cases, complications occurred in intraoperative and early-late postoperative periods. The anastomotic leak rate was 7.1% and the pulmonary complication rate was 22.1% in postoperative complications. The mean hospital stay length was 10.6±8.4 (range, 5-59) days and hospital mortality rate was 2.1%. The median follow-up duration was 37 (range, 2-74) months and the three- and five-year overall survival rates were 61.8% and 54.6%, respectively.

Conclusion: Minimally invasive Ivor-Lewis esophagectomy can be used safely with low mortality and long-time survival rates in esophageal cancer.
Combined pharmacomechanical thrombectomy with selective catheter-directed thrombolysis in patients with acute proximal deep vein thrombosis
Authors: Aldağ Mustafa , Çiloğlu Ufuk
Published: August 2022

Background: The aim of this study was to evaluate the characteristics and the outcomes of combined percutaneous pharmacomechanical thrombectomy with selective catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis.

Methods: Between March 2018 and February 2020, a total of 37 patients (21 males, 16 females; mean age: 55±13.8 years; range, 21 to 79 years) with symptomatic acute iliofemoral vein thrombosis who underwent combined percutaneous pharmacomechanical thrombectomy and catheter-directed thrombolysis were retrospectively analyzed. All patients received a three-step therapy: (i) insertion of a temporary inferior vena cava filter, (ii) percutaneous pharmacomechanical thrombectomy via rotational mechanical thrombectomy device with an adjuvant 0.15 mg/kg recombinant tissue-type plasminogen activator alteplase, and (iii) catheter-directed thrombolysis with continuous 1 mg/h tissue-type plasminogen activator alteplase. Data including demographic characteristics of the patients, bleeding complications, technical success, and adjuvant angioplasty rates were analyzed. The Kaplan-Meier analysis was used to evaluate freedom from re-thrombosis at 3, 6, and 12 months of follow-up was calculated.

Results: The majority of the patients had left-sided (n=22, 59.4%) proximal deep vein thrombosis. Successful insertion of the inferior vena cava filter was achieved in 97.2% (n=36) of patients. The technical success rate was 89.1% (n=33). Adjuvant venous angioplasty was performed in four patients (10.8%) and no venous stents were used. No major bleeding was occurred, while minor bleeding was observed mostly in the form of hematuria (n=12, 32.4%). No mortality was observed. The 3, 6, and 12-month freedom from re-thrombosis rates were 96.3%, 92.6%, and 86.0%, respectively.

Conclusion: Combined percutaneous pharmacomechanical thrombectomy and catheter-directed thrombolysis seems to be an effective and safe treatment of the iliofemoral acute deep vein thrombosis with acceptable minor bleeding complications post-interventionally.
Repair of Gerbode defect and aortic neocuspidization by using bovine pericardium in aortic valve endocarditis
Authors: Ali Şahin Mehmet , Yokuşoğlu Mehmet , Kuralay Erkan , Ertuğrul Özal
Published: August 2022

Aortic valve endocarditis may be destructive and cause an acquired Gerbode-type defect. The use of biological material in the closure of the Gerbode defect and reconstruction of the aortic valve is essential for both early and long-term survival. Herein, we present a 62-year-old male patient whose Gerbode defect was repaired with bovine pericardium. Additionally, the aortic valve was reconstructed by using bovine pericardium with Ozaki neocuspidization technique.
Floating thrombus of the ascending aorta after treatment of ureteral carcinoma: A case report
Authors: George Iosifescu Andrei , Radu Corina , Laura Marin Simona , Enache Roxana
Published: August 2022

An asymptomatic 59-year-old female patient presented with a large floating mass, presumably a thrombus, in the distal ascending aorta. It developed during chemotherapy following nephrectomy for ureteral carcinoma. Due to embolic risks, surgery was indicated. Epiaortic echography revealed embolic risks upon aortic cross-clamping. Aortotomy was performed during brief circulatory arrest under mild hypothermia, followed by safe aortic cross-clamping under direct vision and aortic thrombectomy. The postoperative course was uneventful. Malignancy- and chemotherapy-induced hypercoagulation probably favored thrombus formation. In conclusion, epiaortic echography and short circulatory arrest under tepid hypothermia help to avoid embolic events during ascending aorta thrombectomy.
Surgical mitral valve repair technique considerations based on the available evidence
Authors: Can Tolga , Kirov Hristo , Caldonazo Tulio , Mukharyamov Murat , Färber Gloria , Doenst Torsten
Published: August 2022

Mitral valve regurgitation is the second most common valve disease in the western world. Surgery is currently the best tool for generating a long-lasting elimination of mitral valve regurgitation. However, the mitral valve apparatus is a complex anatomical and functional structure, and repair results and durability show substantial heterogeneity. This is not only due to differences in the underlying mitral valve regurgitation pathophysiology but also due to differences in repair techniques. Repair philosophies differ substantially from one surgeon to the other, and consensus for the technically best repair strategy has not been reached yet. We had previously addressed this topic by suggesting that ring sizing is "voodoo". We now review the available evidence regarding the various repair techniques described for structural and functional mitral valve regurgitation. Herein, we illustrate that for structural mitral valve regurgitation, resuspension of prolapsing valve segments or torn chordae with polytetrafluoroethylene sutures and annuloplasty can generate the most durable results paired with the best achievable hemodynamics. For functional mitral valve regurgitation, the evidence suggests that annuloplasty alone is insufficient in most cases to generate durable results, and additional subvalvular strategies are associated with improved durability and possibly improved clinical outcomes. This review addresses current strategies but also implausibilities in mitral valve repair and informs the mitral valve surgeon about the current evidence. We believe that this information may help improve outcomes in mitral valve repair as the heterogeneity of mitral valve regurgitation pathophysiology does not allow a one-size-fits-all concept.
Cardiac surgery with cardiopulmonary bypass markedly lowers SARS-COV-2 antibody titer
Authors: Şimşek Mustafa , Velioğlu Öcalmaz M. Şeyda , Baştopçu Murat , Sargın Murat , Aksaray Sebahat
Published: August 2022

Background: This study aims to investigate the effect of cardiopulmonary bypass on antibody titers in patients vaccinated against the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) undergoing cardiac surgery with cardiopulmonary bypass.

Methods: Between October 2021 and October 2022, a total of 70 patients (44 males, 26 females; mean age 59.9±10.3; range, 26 to 79 years) who completed their recommended COVID-19 vaccinations and underwent elective cardiac surgery with cardiopulmonary bypass were prospectively included. Serum samples for antibody titer measurements were taken at anesthesia induction and the end of cardiopulmonary bypass after decannulation. The SARS-CoV-2 total immunoglobulin antibodies against N-protein were measured. The antibody titer measurements at anesthesia induction and at the end of cardiopulmonary bypass were compared in all patients.

Results: The median levels after cardiopulmonary bypass were lower than the preoperative levels (1,739.0 vs. 857.0, respectively; p<0.001). There was a drop of 40.0% (21.2%-62.6%) in the antibody titers among all patients. The decrease in antibody titers was consistent regardless of the number of vaccine doses or whether the last dose was received within the last three months. Among the studied factors, no parameter was significantly associated with a lesser or higher decrease in antibody titers.

Conclusion: Cardiac surgery with cardiopulmonary bypass causes a decrease in SARS-CoV-2 antibody titers at the end of cardiopulmonary bypass. Revaccination after cardiac operations may be considered in this patient group that is highly vulnerable due to their comorbidities and lowered antibody levels.
Efficacy of extracorporeal membrane oxygenation in pediatric COVID-19 and MIS-C cases: A single-center experience
Authors: Varol Fatih , Şahin Ebru , Kılıç Aziz , Süleyman Şahin Berkay , Önalan Mehmet A. , Uğur Murat , Tunçer Tunç , Çam Halit
Published: August 2022

Background: This study aimed to evaluate the need and the indication of extracorporeal membrane oxygenation (ECMO) in patients diagnosed with coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) followed up in the pediatric intensive care unit by the demographic, clinical, and laboratory data and treatment response.

Methods: A total of 79 patients (43 males, 36 females; median age: 138 months; range, 6 to 210 months) with COVID-19 and MIS-C followed up between September 2020 - September 2021 were included in this retrospective study. Demographic and clinical data were retrospectively collected from patient files, and clinical data, laboratory findings, chest X-rays, and echocardiography results of six patients (1 male and 5 female, median age: 159 months, range, 13 to 210 months) who needed ECMO due to poor response to medical treatment were recorded before and after the ECMO therapy.

Results: Extracorporeal membrane oxygenation therapy was performed on one patient with a positive COVID-19 polymerase chain reaction test and five patients with MIS-C in our unit. Five patients were supported with venoarterial (v-a) ECMO, and one patient was supported with venovenous ECMO. Median hospitalization time was 29 (range, 24 to 50) days, median Pediatric Risk of Mortality score was 19.5 (range, 11 to 36), and median length of mechanical ventilation was 23.5 (range, 10 to 45) days. The median vasoactive inotropic score was 55.5 (range, 18 to 110) before ECMO, while the median vasoactive inotropic score was 11 (range, 0 to 34) after ECMO. Four patients were successfully weaned off ECMO, and one of these patients was lost due to brain death 15 days after the weaning. One patient infected with the delta variant of COVID-19, which remained positive during the clinical course, and one patient diagnosed with MIS-C was lost despite the v-a ECMO support. Three of the patients were discharged. Thrombosis developed in the superficial femoral artery of one patient on the cannulated side during v-a ECMO. No death due to complications of ECMO was recorded.

Conclusion: In our study, although the majority of our patients followed up with the diagnosis of COVID-19 and MIS-C showed a mild or moderate clinical course, it was observed that a severe clinical course could develop in a small number of patients and that ECMO treatment may be needed in these patients. In agreement with the ECMO studies with different indications in the literature, we conclude that ECMO therapy may markedly contribute to the prognosis in COVID-19 and MIS-C patients when the initiation and termination timing of therapy is correct.
Species, Age and Sex Effect on Thermoregulatory Parameters of Animals in Hot Season of Mubi
Authors:   Department of Animal Production, Adamawa State University, Mubi, Nigeria, Abbaya H.Y , Philimon Y. ,   Department of Animal Production, Adamawa State University, Mubi, Nigeria, Elihu A. ,   Department of Zoology, Adamawa State University, Mubi, Nigeria, Lawal A. U. ,   Department of Animal Health and Production Technology, Federal Polytechnic, Mubi, Nigeria, Lumboyi I. A. ,   Department of Agricultural Education, Federal College of Education, Yola, Nigeria
Published: August 2022

The study was carried out to determine the effect of species, sex and age on thermoregulatory traits of three species of animals in the hot season of Mubi. The species were cattle, sheep and goat. A total of forty eight (48) animals were used, comprising of sixteen (16) each of cattle, sheep and goat that were sourced at international cattle market Mubi. Thermoregulatory parameters taken were, rectal temperature (RT), Respiration rate (RR) and Pulse rate (PR). Heat Tolerance Coefficient was calculated as an index. The thermoregulatory traits measured were subjected to analysis of variance using statistical analysis for sciences (SAS) and means were separated using Duncan Multiple Range Test. Species and sex significantly (P<0.05) affected rectal temperature and pulse rate. The highest recorded rectal temperature was in goat (39.74 0C). The highest pulse rate was in cattle (59.08 beats/minutes). The highest recorded rectal temperature was in male cattle (39.03 0C). The highest pulse rate was in female goat (36.97 beats/ minute), respectively. The highest recorded rectal temperature was in adult sheep (39.03 0C). The highest recoded respiratory rate was in young cattle (72.67 breaths/minute). The highest recorded pulse rate was in young sheep (39.33beats/minute). The highest recoded heat tolerance coefficient was in young cattle (4.48). Respiration rate perfectly correlated positively (P<0.001; r=0.99) with Heat Tolerant Coefficient. It was concluded that sheep had better thermoregulation ability than cattle and goat. This study recommend a provision of sheds at animal’s stands to reduce the direct effect of radiation on the animals at Mubi livestock market
Pengaruh Manajerial Kepala Sekolah dalam Meningkatan Kompetensi Guru PAI pada Pendidikan Dasar
Authors: Muharom Agung , Hermansyah Ade , Nurachadijat Kun
Published: August 2022

Quality education requires human resources, a characteristic of quality education is the collaboration of supervisors, school principals, and teachers who must be able to better manage educational institutions because it will have an impact on teacher competence. Education is the most important element in improving human resources as a whole, because education management must be oriented towards better change. This study aims to determine the managerial influence of school principals in increasing student competence in the field of Islamic religious education. The research used a descriptive qualitative approach, because the symptoms, implications of information and information from the observations during the research process were naural. The results of the study resulted in the First Managerial Planning for school principals in improving student competence in MIN 5 Sukabumi Regency and at SDN CBM Baros Sukabumi City in accordance with predetermined planning procedures or implementing existing aspects. Second, the managerial implementation of school principals in improving student competence in MIN 5 Sukabumi Regency and at SDN CBM Baros Sukabumi City by examining teacher performance documents in detail, and providing guidance and guidance to teachers in improving peadagogical competence. Third, the evaluation of the managerial implementation of school principals in improving student competence in MIN 5 Sukabumi Regency and at SDN CBM Baros Sukabumi City is always carried out to measure the level of success in the implementation of supervision activities.
Penerapan Konsep Manajemen Berbasis Mutu Terpadu Pada Taman Kanak-Kanak Islam Terpadu
Authors: Mansur Adliah , Safwandy Nugraha Mulyawan , Aulia Farida Neng
Published: August 2022

Early Childhood Education is education given to children in the golden age of children (golden age). Education that is in accordance with its development is very important to pay attention to both in terms of process and outcome because it will affect how children's educational experiences at other levels. Attention in education can be viewed from how integrated quality assurance management or Total Quality Management. Research on Total Quality Management in this article was conducted at TKIT / Creative School Azzahra 1 Cisaaat, Sukabumi Regency. The research was conducted using a qualitative approach, data collection techniques using observation, interviews and documentation study. Based on a comprehensive data analysis on the Application of Integrated Quality Management Concept in TKIT / Creative School Azzahra 1 Cisaat, Sukabumi District starting from Planning, Organizing, Implementing, has been carried out well. This is influenced by supporting factors such as the existence of a clear vision and mission of the institution, structured learning objectives, adequate facilities and teachers. However, things that are considered obstacles include leadership and transparency of operational funds. The evaluation and success rate of the application of the concept of integrated quality-based management at TKIT / Creative School Azzahra 1 Cisaat, Sukabumi Regency are good but must be improved.
Penerapan Metode Eksplorasi Lingkungan Sekitar dalam Peningkatan Pengetahuan Sains
Authors: Ramdani Miswan , Muhamad Arsyad Ardi
Published: August 2022

The development of science and technology needs to be introduced to children from an early age, it is hoped that later as a community and the younger generation they can carry out and develop their potential and be responsive to actual problems related to the environment and technology. The purpose of this study was to determine the increase in children's science knowledge in the application of environmental exploration methods in increasing children's science knowledge. In this study, the authors use research methods that are quantitative and qualitative. Quantitatively, the collected data were analyzed descriptively by percentage. The approach used in this study is a Classroom Action Research (CAR) approach, with data collection techniques using observation, interviews, and documentation. The location of the research was carried out at Ananda Ceria Nagrak Kindergarten, Sukabumi Regency. The results of this study indicate that there is an increase in the science knowledge of Ananda Ceria Nagrak Kindergarten students through learning with the exploration method of the surrounding environment, which has been proven by observations on the activeness of students in expressing their scientific knowledge in cycle I and cycle II and cycle III. The teacher's ability to teach with the method of exploring the surrounding environment in cycle I, cycle II and cycle III gets a good category of application to students.
Metode Bercerita Sebagai Penanaman Pendidikan Agama Islam Pada Anak Usia Prasekolah
Authors: Istikhori Istikhori , Agustian Nur Ridwan , Lisanuddin Ramdlani Mohammad
Published: August 2022

The purpose in this study is as follows to find out the implementation of storytelling methods in the learning process of teaching Islamic religious education in Nabila Nagrak Kindergarten and to find out the extent of the success of storytelling methods as the cultivation of Islamic religious education in Nabila Nagrak Kindergarten. This research uses a descriptive research approach. The result of this study is that Islamic religious education instilled in students through storytelling methods helps children to know and understand the teachings in Islam. So that they can practice it in everyday life.
PENERAPAN MEDIA GAMBAR DALAM PEMBELAJARAN PAI PADA ANAK USIA DINI
Authors: Farida Neng Awalia , Agustian Nur Ridwan
Published: August 2022

This study has the potential to enrich educational information, especially in the field of educational technology, and determine visual media and their strategic value for teachers, parents, students, and education practitioners in the school itself. . This type of survey is a qualitative field survey using a descriptive survey method. The data collection method was obtained by using: 1). Observation, 2). Job interview, 3). documentation. Although the data analysis method used is descriptive qualitative. The results showed that the visual media used in PAI learning at RA Nurul Mu'minin Bojonggenteng were still images in the form of posters, caricatures, and cartoons. Video media that are films and VCD images are combined with television. Visual media RANurul Mu'minin Bojonggenteng is used to make teaching methods more communicative and effective. The application of visual media in PAI PAI learning at RA Nurul Mu'minin Bojonggenteng has been successfully implemented.
Monitoring Devices for glucose in critical patients during the COVID-19 pandemic
Authors: Xue Xiujuan , Wang Yeqing , Wang Jing , Zhao Jinyan , Tang Yalin , Song Xueqing , Xu Cuiping
Published: August 2022

Background: Hyperglycemia is common in Intensive Care Unit (ICU) and was reported with high mortality and adverse patients’ outcomes. The infection of COVID-19 is identified as a main source of increase in the incidence of hyperglycemia and associated elevated mortality. In order to reduce the healthcare providers exposure and the personal protective equipment use during the pandemic, the US Food and Drug Administration (FDA) regulated the usage of continuous glucose monitoring (CGM) devices to address these concerns as well as control the glucose level at a desired range. What are the benefits of using CGM applications? The article updates knowledge on this topic.
Methods：We did our search on the following databases: MEDLINE, EMBASE and Cochrane database, articles included were all recent and between January 2020 to July 2022. Our main focus was on articles with evidence concerning the effectiveness and the accuracy of continuous blood glucose monitoring methods in ICU during the COVID-19 pandemic.
Results: A few recent articles were identified and scrutinized. These allow the article to present an overview of the most recent international evidence on the topic, ts benefits and a comparison between methods and devices.
Main Contribution to Evidence-Based Practice: The article puts together the most recent evidence on the demonstrated benefits of continuous glucose monitoring and identifies the few glucose Monitoring Devices about which there is recent published scientific evidence on its application to critical care.
INKULTURASI SEBAGAI USAHA MEWARTAKAN INJIL: KAJIAN EKLESIOLOGIS-HISTORIS PEWARTAAN KEKATOLIKAN DI BALI
Authors: Thomas Kadek Lintang Kurniawan  , Antonius Denny Firmanto  , Nanik Wijiyati Aluwesia
Published: August 2022

This paper discusses the inculturative efforts of the missionaries in spreading the gospel in Bali. The missionaries who came to Bali wanted to bring the Catholic faith into people's lives. Inculturative efforts have become a means for missionaries to spread the Gospel in Bali. They tried to make the gospel present in Balinese society as well. The missionaries interacted with the local community and introduced them to the gospel. Through this interaction, the development of the Bible in Bali is still well preserved. This research used historical method. The author traced the history of the inculturation of the Catholic faith in Bali. The results of this research show that this inculturation effort didn’t run smoothly. Many challenges come such as restrictions on reporting, exile, death threats and so on. The missionaries interacted with the local community and introduced the gospel. Through this interaction, the development of the Bible in Bali is still well preserved. It can be seem from architecture of the church building with Balinese cultural nuances, the singing of the inculturation mass in Balinese, the Eucharist in Balinese and so on. Therefore, Catholicism in Bali has survived. Most of the Catholics in Bali still maintain the legacy of the missionaries and try to be grace of the world.
Analysis of Infrastructural Challenges, Cybercrime, and the Cashless Policy in Nigeria
Authors: Musa Ibrahim , Magaji Sule , Hassan Abul-Azeez
Published: August 2022

Abstract

This study makes an analysis of infrastructural challenges and the cashless policy in Kaduna state, Nigeria. A survey was conducted to collect the primary data through a structured questionnaire and interviews with bank customers, bank officials, and security personnel to obtain information on infrastructural challenges since the introduction of the Cashless policy by the Central Bank of Nigeria in 2012. Frequency distribution and simple percentage methods are used to analyze the data.  Findings show that infrastructural challenges include network failure and infrastructural deficiency, debiting by Automated Teller Machine (ATM) without disbursing cash to beneficiaries, problems not rectified quickly by the banks, and charging by banks for using electronic banking methods. This leads to fraud, cybercrimes, and reduced confidence in the banking system. It is recommended that banks should be made to provide the minimum infrastructure required for cashless policy to succeed. In addition, there should be adequate cyber security measures implemented by banks and the government.
ISOLATION AND ACTIVITY ANTIBACTERIAL OF ISOLATES ENDOPHYTE FUNGI OF JATROPH MULTIFIDA L. STEM
Authors: Herwin Herwin , Kosman Rachmat , Wahyuni Sri
Published: August 2022

Endophytic fungi that live on plant tissue has the potential to produce secondary metabolites, same as its host. This study aims to isolation endophyte fungi and antibacterial activity of isolate endophyte fungi of Jatropha multifida L. stem to Escheriacia coli and Staphylococcus aureus bacteria. The preliminary research was performed by isolation endophyte fungi of Jatropha multifida L. stem use PDAC medium and the result of isolation endophyte fungi Jatropha multifida L. stem obtained 6 isolates. Isolates endophyte fungi done examination morphology by microskopic method obtained that islolates have different carasteristic. Based on examination of antibacterial activity by agar diffusion method showed that isolates endophyte fungi that potential as antibacterial is isolate IFJT1 code where isolate IFJT1 code active to Escheriacia coli bacteria obtained inhibitory zone diameter of 17,7 mm and to Staphylococcus aureus bacteria.obtained inhibitory zone diameter of 16,7 mm
IDENTIFICATION AND ANTIBACTERIAL ACTIVITY TEST OF ENDOPHYTE FUNGI MAHONI BARK (Swieenia mahagoni L.) IFKBM04
Authors: Nuryanti Siska , Rosdah Rosdah , Naid Tadjuddin , Hardiyanti Vivi
Published: August 2022

Endophytes represent a complex community of microorganisms colonizing asymptomatically internal tissues of higher plants. Several reports have shown that endophytes enhance the fitness of their host plants by direct production of bioactive secondary metabolites. This study investigated the antibacterial activity of endophytes fungi IFKBM04 isolated from Swietenia mahagoni L. and identified macroscopic and microscopic characteristics of endophytic fungi. Based on the results of macroscopic and microscopic identification compared with the literature to determine the general characteristics of the sample. The results of this morphological identification showed that the sample of mahogany bark isolate (Swietenia mahagoni L.) code IFKMB-04 had similarities with the genus Saccharomyces sp.
ANTIBACTERIAL ACTIVITY OF PATCHOULI OIL REFINERY WASTE AGAINTS STAPHYLOCOCCUS AUREUS BACTERIA
Authors: Sarmila Sarmila , Razak Abd. Rahman , Jamaluddin Jamaluddin
Published: August 2022

Patchouli oil refining waste is biomass or organic waste which has chemical contect so that it has antibacterial potential. This study aims to determine the antibacterial activity of patchouli oil refining waste against Staphylococcus aureus and knowing the groups of compounds identified as having antibacterial activity after the TLC Bioautography test was carried out. The sample was extracted using the maceration method with 96%  ethanol solvent. Antibacterial activity testing was carried out with a concentration variant of 50%, 25% and 10% with the well method. Thin layer Chromatography (TLC) using n-hexane : ethyl acetate (3:1) elucants. TLC Bioautography using contact bioautography method. From the research that has been done, it is found that the ethanol extract of patchouli oil refining can inhibit Staphylococcus aureus which has the largest diameter of resistance with a concentration of 50% which is categorized as very strong. The results of the TLC Bioautography study showed the saponin compound class after being sprayed with H2SO4 10% reagent, it was found that the ethanol extract of patchouli oil refined pulp has antibacterial activity against Staphylococcus aureus and compounds to play a role in antibacterial activity are saponins.
Investitionskontrolle in Deutschland
Authors: Dehne Bodo
Published: August 2022

Investment control has become one of the "hot topics" in M&A in recent years. Using the example of foreign sovereign wealth funds, the German foreign investment control regulations as well as further possibilities under German foreign trade law to control foreign investment are illustrated. In addition, the Union competence for foreign direct investments and the ECJ case law on the freedom of capital and the freedom of establishment are analyzed and it is argued why the existing German investment control is not compatible with EU law. The author is a lawyer in the area of corporate/M&A with a focus on investment control and has substantial practical experience in foreign investment control proceedings.
Design method of intangible cultural creative products based on pharma Industries Ethics Education among Educators
Authors: Xu Fan
Published: August 2022

In order to solve the problem of low image fusion caused by the high cost of clustering calculation in the design of intangible cultural creative products, a design method for intangible cultural creative products based on AI painting generation is proposed for pharma companies. The intangible cultural heritage image is extracted and segmented. The image is divided into different regions according to the gray level of pixels, and the edge detection algorithm of images in different regions of the product is designed to make the region near the picture more fit. The fusion image of intangible cultural heritage features is generated based on AI paintings, so as to reduce the cost of clustering calculation and complete the splicing of artistic style. Build the design model of intangible cultural creative products, combine the design creativity, and realize the mutual integration of intangible culture and products. Construct four image sample sets of scenic spots and historic sites, religious beliefs, festival folk customs and handmade, and test the fusion degree. Taking the festival folk custom image set as an example, the average fusion degree of this method is 0.773, which is 0.133 and 0.145 higher than the comparison method based on convolutional neural network and machine learning, respectively. Therefore, it has good application effect.
Application of wireless network communication technology in interior decoration system and Commercialization of hospital buildings
Authors: Luo Yuanxiang
Published: August 2022

In view of the low accuracy of signal perception caused by unbalanced task allocation of high-rise hospital building interior decoration system, a high-rise building interior decoration system is designed based on wireless network communication technology. Hardware part: the terminal node based on STM32 MCU is connected with the environment sensor, and the BC35-GNB-IOT communication module is set to ensure the anti-interference of the link. In the software part, the angular power spectrum is used to establish the indoor communication scene classification model of high-rise hospital buildings, the task is divided into several sub-tasks according to the time complexity, and the wireless network is used to realize the dynamic scheduling of tasks. The indoor environment sensing algorithm is designed to detect the performance of cyclostationary signals. It shows that the sensing accuracy of the system designed in this paper is higher than that of the system without a wireless network, which has good robustness and can improve the service quality of indoor environmental monitoring.
Spirituality in oncology - a consensus by the Brazilian Society of Clinical Oncology
Authors: Toloi Diego de Araujo , Landeiro Luciana Castro Garcia , Gadia Rodolfo , Chaves Cristiane de Lacerda Gonçalves , Forte Daniel Neves , Castilho Rodrigo Kappel , Garcia João Batista Santos , Andrade Carlos Jose Coelho de , Gaui Maria Fátima , Machado Maria Cecilia Mathias , Mathias Clarissa
Published: August 2022

Spirituality is a dynamic and an intrinsic aspect of humanity and is usually intense in cancer for patients, families, and health care teams. Evidence on spirituality, health, and healing have increased over the last decades. This consensus is for those involved in cancer patient care, with concepts and possible strategies for addressing spirituality, with discussion on the relevance, impact, and challenges of spirituality care. The purpose and intent of the consensus are to highlight the need for spirituality inclusion in the complex and delicate trajectory of cancer patients.
Breast milk components and factors that may affect lactation success
Authors: Miolski Jelena , Raus Mišela , Radusinović Milica , Zdravković Vera
Published: August 2022

Introduction. Breastfeeding is the most important way to feed a newborn, infant and a young child. Lactogenesis is the ability of secreting milk from the mammary gland and includes secretory initiation and activation. The birth of the placenta and decrease in progesterone levels stimulate an increase in prolactin levels and the secretion of milk from the breast. Human milk contains carbohydrates, lipids, proteins, vitamins, minerals, fatty acids, amino acids and trace elements. In addition, numerous cells, macrophages, bacteria, chemokines, cytokines, immunoglobulins, hormones, growth factors, and mucin are present. The composition of milk differs depending on the phase of secretion. Colostrum is secreted for the first five days after birth, then comes transitional milk, and mature milk two weeks after birth. During the very act of breastfeeding, there is a difference between pre-milk and last milk. In pre-milk, the fat content is low and increases with the duration of lactation, and in breast milk it is relatively high. Aim: To point out the importance of milk composition and factors that are influential for breastfeeding. Conclusion: Maternal parity, age or socioeconomic status and education can affect the concentration of certain components of breast milk. Adequate social policy and support, along with education related to early breastfeeding experiences, can be the key factors in initiating and maintaining breastfeeding. Besides the mother and the child, the entire social community would benefit from that.
The importance of cash flow analysis
Authors: Ševkušić Ljubiša , Bodiroga Radomir
Published: August 2022

For the economy of the Republic of Serbia, agriculture is a very relevant branch. Its significance and its place is reflected in the fact that in the creation of GDP it participates with about 6,5%. This percentage is significantly increased if one takes into account that agriculture contributes greatly to the development of other sectors of the economy, primarily to producers and processors of inputs and raw materials. In addition, it is characterized by a relatively high employee share, significant natural, technical, technological and other potentials. However, regardless of the mentioned potentials, it is evident that agricultural enterprises in Serbia do not realized the business results expected of them. For this reason, before the management, a big task which is reflected in making business decisions, which will significantly contribute to the successful operation of these companies. Significant and very useful information for the realization of the give task provides analysis of cash flows. In this regard, the main goal of the work is to look at and point out the usefulness of information obtained by analyzing cash flows. The results of the research show that the analysis of cash flows significantly enriches the information base, which significantly facilitates the decision-making and management process of the company.
Attitudes of managers about the advantages and disadvantages of internal audit of accounts on social networks
Authors: Jakovljević Nemanja
Published: August 2022

Social networks can have a significant impact on an organization's operations, on the performance and results of its operations. The social networks accounts audit can be an independent review of relevant activities and other subject issues from the impact on accounts on social networks with the aim of issuing an independent professional opinion on the status and performance of accounts on social networks. Social networks account management is a strategy and risk-based approach for establishing protection mechanisms and strategic activities related to social media accounts, such as brand protection, brand promotion, customer protection, acquiring new customers, communicating with customers and more. The subject of research in this paper is to examine the attitudes of managers about the advantages and disadvantages of internal social networks accounts audit. The main conclusion of the paper is that managers point out the control function in the field of business regularity as the advantage of internal audit in the field of social networks, ie., providing a certain type of assurance on compliance of social media activities with strategic guidelines and internal rules and procedures of the company, while the insufficient level of knowledge of persons engaged in auditing activities on social networks is stated as a flaw.
Du bon usage satorien de la théorie bakhtinienne du chronotope
Authors: Dubost Jean-Pierre
Published: August 2022

Bien que très souvent les satoriens évoquent Bakhtine dans leurs analyses ou s’appuient même partiellement sur tel ou tel aspect de son oeuvre, la SATOR n’a jamais mené de débat de fond autour de l’oeuvre de Bakhtine, alors que les références à Propp ou Thomson  sont plus fréquentes. Ce n’est pas un hasard. La  théorie bakhtinienne du chronotope est souvent utilisée autant dans la recherche que dans l’enseignement et nos étudiants sont souvent invités à la prendre en compte, mais rares sont les travaux qui en prennent en compte toute la complexité, et le cercle des spécialistes de l’oeuvre de Bakhtine en mesure d’appréhender ses nombreuses adhérences  - et notamment son double positionnement à la fois face au formalisme russe et à l’esthétique générale allemande et autrichienne de la fin du XXe et du début du XXe - est assez restreint. Très souvent on ne retient par exemple de l’oeuvre de Bakhtine que le concept de dialogisme, alors que ce n’est qu’un aspect de la théorie. Le but de cet article est de faire la synthèse des nombreuses attaches et  des différents moments de la théorie du chronotope, laquelle s’enracine profondément dans une esthétique générale et présuppose une certaine conception du temps historique et des rapports entre littérature et société. Tout autant que l’analyse topique, cette théorie  met en évidence le rôle central que le genre  romanesque  joue dans la culture européenne depuis l’Antiquité. Mais elle implique  aussi une conception spécifique de l’articulation entre le devenir historique et l’espace-temps de la fiction. Parce que la thématique de ce numéro est l’occasion de faire le point sur ce sujet majeur, cet article se propose de montrer en quoi la prise en compte de la part topographique de l’analyse topique rencontre la question du chronotope et en quoi elle ne peut faire plus que la croiser. Car ce que l’analyse topique dégage de la répétition ne repose pas sur la même idée d’une « plénitude » du temps historique que celle qui constitue le socle de la théorie du chronotope. Mais elle n’est pas pour autant anhistorique. En fait c’est ici toute la question du statut de l’authenticité romanesque entre hasard et nécessité qui est en jeu. Ce qui nous renvoie à la question, soulevée dans l’introduction de ce numéro, du statut proprement poétologique de la récurrence romanesque et des paradoxes de temporalité indissociables de l’analyse topique au sens où  la SATOR la pratique.
Existe-t-il une définition topique de la rencontre comique ? (Sur quelques romans comiques européens des XVIe et XVIIIe siècles)
Authors: Tran-Gervat Yen-Mai
Published: August 2022

Les deux sens de « comique », dans l’expression telle que je l’entends, « qui s’apparente à la comédie » et « qui suscite le rire », se rejoignent et se complètent, on le verra, au sein d’une structure récurrente qui est surtout visible dans les situations où s’opère une rencontre, celle du contraste marqué, surprenant, entre le haut et le bas, que les Anglais du Scriblerus Club nomment « bathos ». Un tel contraste est au fondement du burlesque et de l’héroï-comique, mais aussi bien souvent de la parodie, du ridicule, ou encore du comique farcesque. Cette structure contrastive, bien que récurrente, est cependant trop vaste, trop générale pour être considérée comme un topos qui pourrait se formuler : « contraste haut-bas ». La question de la rencontre nous donne l’occasion de la décliner en topoï plus précis, aussi bien narratifs qu’énonciatifs, qu’il s’agira ici de définir. Le corpus sur lequel portera ma réflexion est le suivant (dans l’ordre chronologique) : Don Quichotte (1605-1615) de Cervantès, L’Histoire comique de Francion (1623) de Sorel, Le Roman comique (1651-1657) de Scarron, Le Roman bourgeois (I 666) de Furetière, Pharsamon (1e édition, 1737 ; 1e privilège, 1713) et Le Télémaque travesti (1e édition, 1736; 1e privilège, 1714) de Marivaux, Gil Blas (1715) de Lesage, Joseph Andrews (1742) et Tom Jones (1749) de Fielding, The Female Quixote (1752) de Lennox, Tristram Shandy (1759-1766) de Sterne, Jacques le Fataliste de Diderot (1771-1783); autant de romans qui, notamment, interrogent le romanesque même par le recours au comique.

L’enjeu d’une telle réflexion est au moins double : il s’agit bien sûr de contribuer à l’étude collective, dans le cadre de ce recueil, de la « topographie de la rencontre dans le roman européen », en prenant la question sous l’angle du rire et du comique. Mais c’est aussi l’occasion de poser la question du rapport entre roman et théâtre dans la période qui nous occupe, à travers la mise en oeuvre de topoï communs aux deux genres; c’est pourquoi j’ai tenu d’entrée de jeu à expliciter la polysémie de l’adjectif « comique ». De même, j’exploiterai la polysémie de la notion même de « rencontre », que je propose d’examiner non seulement dans un sens concret, celui de la mise en relation de personnages dans le temps et l’espace du roman, mais aussi dans un sens plus métaphorique, voire métatextuel, celui de l’entrelacement de schémas dramatiques et narratifs comme contribuant à l’élaboration d’un roman certes comique, mais aussi critique et réflexif.

Pour ce faire, je propose donc d’aller et venir entre le « topographique », l’étude des lieux de rencontre, et le métaphorique. Un lieu privilégié de rencontres comiques, l’auberge, nous servira de point de départ et de fil d’Ariane pour cette exploration des différents types de rencontres comiques qui se présenteront sur notre chemin.
Les affinités sélectives
Authors: Duché-Gavet Véronique
Published: August 2022

Situé au confluent de plusieurs traditions littéraires, le roman de la première Renaissance explore avec attention le domaine sentimental. Mais s’il se focalise tout particulièrement sur le sentiment amoureux, il ne néglige pas pour autant la place accordée à l’amitié. Ces affinités sélectives, qu’il s’agisse de l’amitié qui unit deux personnes du même sexe ou bien de la « parfaite amitié », mettent toutefois souvent en jeu un troisième élément qui vient perturber la relation amicale. En effet, la fiction sentimentale vient nourrir le débat sur le rôle des passions, qui agite alors les milieux intellectuels.

Notre étude parcourt les romans sentimentaux et humanistes du « beau seizième siècle » à la recherche du triangle érotique que forment l’amant, l’amie et l’ami. Dans un esprit satorien, nous analysons les topoï narratifs qui lui sont associés.
Amitié, solidarité et entraide féminines : spécificités d’auteurs femmes ?
Authors: van Dijk Suzan
Published: August 2022

Dans cet article je réfléchis sur l’éventuelle spécificité des narrations féminines, et notamment sur l’emploi de certains topoï narratifs.

À la question « comment repérer ces topoï "féminins" ? », je donne comme réponse : par le recours à certains « topoï de la réception », bien spécifiques et susceptibles de nous orienter dans la bonne direction.
Les « amis charnels » : fraternité et communauté spirituelle dans le Lancelot-Graal
Authors: Dupuy Marie
Published: August 2022

L’expression ami carneus, récurrente dans le Cycle Vulgate, contient le paradoxe d’un lien qui se fonde à la fois sur une parenté charnelle, sens premier de l’expression, et sur une relation spirituelle, celle de l’amicitia; elle révèle donc les contradictions d’une parenté à la fois assumée et à amender. En effet, l’étude de ses occurrences dans le Lancelot-Graal permet de définir deux grands types de rapports entre les personnages. Les uns, horizontaux, sont fondés sur une élection et mettent en évidence un réseau de parenté diffus, allant des plus proches parents aux plus lointains et surtout, définissant un cercle privilégié d’intimes; les autres, verticaux, relèvent de l’alliance et du lien féodo-vassalique unissant parfois d’ailleurs les membres d’une même parentèle, reposent sur la fides et paraissent nettement valorisés. L’ambiguïté de l’expression repose sur l’usage spécifique qui se dessine dans son emploi en langue vernaculaire : les amis carneus entretiennent des relations de confiance et de fidélité à l’opposé des amitiés charnelles telles que les décrit le discours théologique, celui d’Aelred de Rielvaux en particulier. Il est de plus remarquable de constater que les mentions qui sont faites des « amis charnels », le sont toujours dans des moments de crise. À ce titre, la crise seigneuriale qui ouvre le Lancelot propre est particulièrement intéressante : ayant pour origine la domination des terres par les dominants laïcs, elle oppose Claudas l’usurpateur à Pharien, fidèle au lien qui le lie à son ancien seigneur, Bohort de Gaunes, le roi déchu. Or, Claudas est un roi défaillant qui a tissé un réseau d’alliances reposant sur des amitiés charnelles au sens où l’entend l’abbé de Rielvaux : intéressées et monnayables, elles révèlent un mauvais dominant laïc qui a fondé son pouvoir sur l’avaritia et la potentiae cupiditas. À l’opposé, ses ennemis recourent à leurs « amis charnels » parce que les liens qui les unissent reposent au contraire sur la fides et l’amor, l’alliance redoublée par la parenté. On voit ainsi, dans un épisode exemplaire de renversement des alliances, Lambègue, le neveu de Pharien, secourir son oncle avec qui il était brouillé, au nom de la carnel amor qui les unit : la pitié qui guide l’élan du neveu révèle le modèle sous-jacent de circulation de la caritas entre grands seigneurs laïcs. Capables ainsi d’une forme d’amitié parfaite parce qu’assises sur des liens naturels, l’oncle et le neveu se placent dans l’imitation de la relation verticale qui unit le chrétien à Dieu et peuvent alors refonder l’ordre féodal mis à mal par le traître. Cet épisode, en réorganisant la hiérarchie spirituel / charnel au profit du charnel, met en évidence une charnalité assumée puisque vectrice d’une bone amor faite de pitié et de miséricorde, charnalité qui, paradoxalement, conduit à une forme de spiritualisation de la chevalerie.