bluuebunny/crossref_metadata_2025 huggingface dataset:
PEDIATRIC FRACTURES IN A TERTIARY PUBLIC HOSPITAL: WHAT ARE WE DEALING WITH?
Authors: Almeida Leonardo Lima de , Engel Edgard Eduard , Volpon Jose Batista
Published: February 2025

Abstract Objective: Orthopedic trauma is significant in modern society due to its incidence and its impact on healthcare and social interactions. Concerns include the risk of permanent sequelae affecting individual development and causing social stigma. Fractures, while not the most lethal lesion, may result in physical variable disability; publications show that about 30% of children experience fractures by skeletal maturity, primarily from low-energy trauma. This study aims to identify the fracture patterns in the immature skeleton at a tertiary-level public hospital. Methods: Individuals with skeletally immature fractures of the locomotor system, treated at a tertiary-level emergency unit from January 2016 to January 2020, were included. Data collected included social characteristics, trauma origin, fracture descriptors, and treatment modality. Age groups: infant, preschool, school-age, adolescent. Trauma energy is classified as low, moderate, or high. Results: A total of 926 cases were recorded in 505 patients, with a predominance of males. The most affected bones were the radius (29.5%), humerus (24.2%), and ulna (15.8%). The metaphysis was the most common location (46.7%), followed by the diaphysis (33.2%). Falls accounted for the largest portion, at 64.7%, with the majority (364) being low-energy trauma. High-energy trauma, such as pedestrian accidents and car accidents, represented 13.7%, and of these, 54.2% were polytraumatized. Conclusion: Fractures of the forearm persist as the most common, particularly at the distal third of the radius, with males being more exposed. Climatic seasonality and cultural traits such as soccer practice have little impact on the epidemiology of fractures. The results obtained in this investigation resemble those obtained by international literature. Level of Evidence III; Retrospective Cohort Study.
Situación vacunal de personas con diabetes mellitus asistidas en la Atención Primaria de Salud: estudio transversal
Authors: Carvalho Neto Francisco João de , Lima Luisa Helena de Oliveira , Gamba Mônica Antar , Brito Rosilane Lima de , Silva Lucilane Maria Sales da , Silva Ana Roberta Vilarouca da
Published: February 2025

Objetivo analizar la situación vacunal de personas con diabetes mellitus tipos 1 y 2 en la atención primaria de salud. Método estudio transversal, analítico, realizado en 25 equipos de Salud de la Familia con 274 personas con diabetes. Se evaluaron las variables sociodemográficas, clínicas y el esquema vacunal completo para cada vacuna recomendada por el Programa Nacional de Inmunizaciones mediante un análisis bivariado y regresión logística. Resultados de las personas con diabetes mellitus, el 69,1% no contaba con el esquema vacunal completo contra la hepatitis B; el 64,6% contra la difteria y el tétanos; el 74,3% contra la fiebre amarilla; el 87,9% contra el neumococo; el 87,9% contra la varicela; el 24,5% contra influenza y el 0,7% contra la COVID-19. Entre los motivos aludidos para el esquema vacunal incompleto, figuran no conocer la importancia de vacunarse y no haber sido informado por el profesional de la salud. Hubo asociación estáticamente significante entre el perfil sociodemográfico y clínico con relación al esquema vacunal completo entre la vacuna contra la influenza y la edad y los ingresos; COVID-19 y edad, tipo de diabetes y tiempo viviendo con diabetes. Conclusión las personas con diabetes mellitus tipos 1 y 2 presentaron baja completitud de las vacunas en el contexto de la Atención Primaria de Salud, lo que es preocupante debido a la situación de mayor vulnerabilidad a infecciones inmunoprevenibles y mortalidad en este grupo.
Síntomas prevalentes y características de la población en la COVID prolongada: una revisión de alcance
Authors: Prediger Karina Marques , Ribeiro Ana Cristina , Uehara Sílvia Carla da Silva André
Published: February 2025

Objetivo: mapear la literatura científica sobre las características clínicas y demográficas de la COVID prolongada. Método: se trata de una revisión de alcance basada en los principios recomendados por el JBI y las directrices del PRISMA para la extracción de datos, realizada a partir de cuatro bases de datos. Se utilizó la estrategia PCC para la recolección de datos, siendo los resultados descritos y diagramados. La selección de los estudios se realizó después de la eliminación de duplicados, evaluación individual y en pares. Resultados: un análisis de los 13 artículos seleccionados mostró que la COVID prolongada afecta a todas las franjas etarias y a personas de ambos sexos, presentando una multiplicidad de síntomas, como fatiga (61,5%), disnea (46,1%), alteraciones en el olfato y/o gusto (38,6%), ansiedad (15,3%) y deterioro cognitivo (30,7%). En el sexo femenino se identificó un mayor riesgo de desarrollar COVID prolongada. Conclusión: la identificación de los síntomas prevalentes en la COVID prolongada contribuye a la estrategia de salud pública, para el diagnóstico y asistencia a las personas afectadas por la enfermedad. Se recomiendan estudios futuros sobre el abordaje de la persistencia de los síntomas en la COVID prolongada y la relación de la adherencia al esquema de vacunación contra la COVID-19, sexo, raza/etnia, grado de susceptibilidad en las diferentes franjas etarias, nivel educativo e ingresos, además de las comorbilidades más frecuentes en la población.
Improving okra performance through pollinator attractors
Authors: Correa Ronald Lucas da Silva , Carvalho Eliana Cristina Moreira de , Latini Anderson Oliveira , Dias Igor de Paula , Reis Gercino José dos , Silva Moisés Lucas Avelar da
Published: February 2025

ABSTRACT The vicinity of natural areas can enhance availability of pollinators and crop productivity. Considering the global reduction of pollinators and the global food insecurity, innovative strategies to enhance pollination and crop yield are important. Thus, we investigated the efficacy of using colored attractors of pollinators to improve okra yield. The use of pollinator attractors led to a significant increase in the length, volume, and weight of okra in comparison to plants without attractors, and notably larger when compared to plants without pollinator access. Although uncertainties remain regarding scalability and optimal implementation, our results emphasized the opportunity of the colored attractors, a low-cost intervention, to boost food productivity and alleviate food insecurity.
Microbial signatures in head and neck squamous cell carcinoma: an in silico study
Authors: KAVITHA Loganathan , KUZHALMOZHI Manogaran , VIJAYASHREE PRIYADHARSINI Jayaseelan , ARUN KUMAR Arunachalam , UMADEVI Krishna Mohan Rao , RANGANATHAN Kannan
Published: February 2025

Abstract Objectives The oral cavity harbors a plethora of bacterial species. Dysbiosis of oral and gut microbiota is associated with several oral and systemic pathologies, such as cancer, obesity, diabetes, atherosclerosis and gastrointestinal diseases. Imbalance in the oral-gut microbial axis has been associated with head and neck squamous cell carcinoma (HNSCC). This study aims to analyze the bacterial profile of HNSCC across various taxonomic units, investigate molecular patterns associated with prevalent bacterial phylum in HNSCC, and compare the bacterial profile in HNSCC and gastrointestinal (GI) carcinoma using computational analysis. Methodology The microbe-host transcriptomic, proteomic, and epigenetic analyses of HNSCC and GI carcinomas were performed using The Cancer Microbiome Atlas (TCMA) database. The differential expression of the host’s mRNA transcripts and proteins associated with tumor microbiome were analyzed using The University of Alabama at Birmingham Cancer data analysis (UALCAN) and Clinical Proteomic Tumor Analysis Consortium (CPTAC) websites. Results A decrease in Actinobacteria and an enrichment of Flavobacteria at the class level, Neisseriales, Pasteurellales, and Campylobacterales at the order level, Pasteurellaceae, Flavobacteriaceae, Campylobacteraceae, and Peptoniphilaceae at the family level, and Hemophilus, Porphyromonas, and Leptotrichia at the genus level were observed in HNSCC compared to the normal mucosa. RICTOR protein, mRNA transcripts (HIST1H2BB, SCARNA11, TBC1D21 gene), and hsa-miR-200a-5p miRNA were significantly correlated with prevalent bacterial species in HNSCC. A major increase in Actinobacteria, Fusobacteria, and Spirochaetes was observed in HNSCC compared to GI carcinoma. Conclusion The oral-gut microbial dysbiosis, as reflected by the differential abundance of bacterial species in oral and GI carcinomas, suggests the implication of tumor microbiome and their genomic interactions with the host in carcinogenesis.
The effects of Stemregen® host modulation therapy on experimentally induced apical periodontitis in rats*
Authors: GÖNÜLLÜ Fatma , OCAK Mevlüt Sinan , DUNDAR Serkan , ÖZERCAN İbrahim Hanifi
Published: February 2025

Abstract This study evaluated the effect of Stemregen® nutritional supplement on inflammation and resorption in apical periodontitis using a rat model. Methodology Rats were divided in three groups: negative control (n=7), positive control (n=10), and Stemregen® (Stem) (n=10). Apical periodontitis was induced in the positive control and Stem groups, and all rats were sacrificed on the 30th day. Serum phosphorus (P), calcium (Ca), and alkaline phosphatase (ALP) were analyzed. Histopathological assessments measured osteoblastic and osteoclastic activity, inflammation, fibrosis, and abscess density. Immunohistochemical analyses evaluated RANKL, TRAP, and OPG levels. Results Results showed significantly lower osteoblastic activity in the negative control compared to Stem and positive control groups (p=0.005). Osteoclastic activity was higher in the positive control (p=0.032). Inflammation and abscess formation were reduced in the Stem group compared to the positive control (p<0.001). OPG levels were lower in the negative control compared to the other groups (p=0.005). Conclusion Stemregen® effectively reduced inflammation and bone destruction, suggesting potential benefits for apical periodontitis management, though further research is needed.
Covid-19 and food systems in the Agriculture Ministries' symbolic agendas of Brazil, Chile, and Colombia
Authors: Grisa Catia , Vasconcellos Fernanda Castilhos França de , Marques Ingrid de Paula , García Gonzalez Nicol Manuela , Narciso Isabela Zacher
Published: February 2025

Abstract Several studies have argued that the COVID-19 pandemic could be a catalyst for building sustainable food systems. Among the actors involved in this debate, we emphasize the significance of agriculture ministries in shaping governmental agendas and policies. Starting from debates on agenda-setting, this article analyzes how the Covid-19 pandemic manifested itself in the symbolic agenda and the issues related to food systems prioritized by the agriculture ministries of Brazil, Chile and Colombia, reflecting on the contents of Facebook throughout 2020. In methodological terms, the article mapped the posts, selected those related to the Covid-19, analyzed and classified into categories. The results indicate that the ministries paid different attention to the pandemic, however, in all cases, the pandemic lost space on the symbolic agenda in the second half of 2020. Contrary to expectations of transformative change, the ministries' posts aimed to maintain existing dynamics in food systems.
OS SENTIDOS DO TRABALHO PARA ADOLESCENTES EXPLORADOS PELO TRÁFICO DE DROGAS
Authors: Melo Beatriz Pinheiro de , Paulino Daniele , Bendassolli Pedro F. , Coelho-Lima Fellipe
Published: February 2025

Resumo O objetivo desta pesquisa foi analisar os sentidos do trabalho para adolescentes explorados pelo tráfico de drogas. Com base na Psicologia Histórico-Cultural, realizamos entrevistas semiestruturadas com adolescentes com histórico de exploração pelo tráfico de drogas. A análise do núcleo de significação das falas permitiu apreender quatro eixos que se referem a complexas nuances que demarcam o tráfico de drogas como um trabalho. Concluímos que o sentido do trabalho no tráfico para esses adolescentes é marcado também por contradições objetivas e subjetivas quanto ao trabalho e ao tráfico; à moral comum e à busca pelo consumo.
“YOU AIN’T WHITE. ARE THEY WHITE?”: O “BRANCO VERDADEIRO” EM BACURAU (E NO BRASIL)
Authors: Mattos Amana Rocha , Schucman Lia Vainer
Published: February 2025

Resumo Neste artigo, discutimos a noção de “branco verdadeiro” e as hierarquias intrarraciais da branquitude, considerando a constituição histórica das categorias raciais brasileiras. Alicerçada na ideologia do embranquecimento vigente no Brasil, a noção de “branco verdadeiro” encontra-se tanto em teorizações acadêmicas quanto em expressões midiáticas e artísticas, mesmo naquelas que se destacam pela crítica social. Tomamos como analisador uma cena do filme Bacurau para pensar as narrativas da branquitude sobre ser branco/a no Brasil, assim como postagens em redes sociais, articulando-as com o mito da democracia racial e a ideia de miscigenação que vigora no país – inclusive em setores progressistas. Como resultado, indicamos que um dos problemas da suposição de que no Brasil não haveria brancos/as “verdadeiros” é contribuir para a desresponsabilização da população branca em relação à desigualdade racial e pode colocar em descrédito as discussões sobre a redistribuição antirracista de recursos e oportunidades no Brasil.
Physiological aspects and growth of cashew under salt stress and salicylic acid in pre-flowering phase
Authors: Arruda Thiago F. de L. , Silva André A. R. da , Azevedo Carlos A. V. de , Lima Geovani S. de , Carvalho Guilherme S. de , Costa Denis S. , Borborema Lucyelly D. A. , Nunes Kheila G. , Gheyi Hans R. , Soares Lauriane A. dos A.
Published: February 2025

ABSTRACT The use of water with high concentration of salts in cashew cultivation is a necessity in the semi-arid region of Northeast Brazil, due to water scarcity and poor rainfall distribution. Excess salts in water are a limiting factor for agricultural production. In this scenario, strategies have been employed to mitigate the harmful effects of salt stress on plants, and the use of salicylic acid stands out. With this, the aim of this study was to evaluate the effects of foliar application of salicylic acid on the physiology and growth of early dwarf cashew grown under salt stress in the pre-flowering stage. The experiment was conducted in a greenhouse using a randomized block design, in a 5 × 4 factorial arrangement, with five levels of electrical conductivity of irrigation water (ECw - 0.4, 1.2, 2.0, 2.8, and 3.6 dS m-1) and four concentrations of salicylic acid (SA - 0, 1, 2, and 3 mM), with three replicates. Salicylic acid, applied at a concentration of 1 mM, mitigated the negative impacts of salt stress on the morphophysiology of cashew during the pre-flowering phase, especially in plants irrigated with ECw of up to 1.2 dS m-1. On the other hand, the concentration of 3 mM SA exacerbated the effects of salt stress on the relative water content, electrolyte leakage, photosynthetic pigments, gas exchange, and growth of early dwarf cashew, particularly at ECw of 3.6 dS m-1.
Práticas de literacia informacional das plataformas Educamídia durante a pandemia de covid-19
Authors: Tomé Rafael Ferreira , Brasileiro Fellipe Sá
Published: February 2025

Resumo: Este artigo objetiva compreender as práticas de informação das plataformas do programa Educamídia orientadas à promoção da literacia informacional durante a pandemia. Recorre ao método netnográfico para observar as atividades agenciadas pelas plataformas. Constata que a promoção da literacia informacional no ecossistema digital do Educamídia ocorreu por meio das seguintes práticas dispersas: conscientização sobre desinformação; formação docente-pedagógica; recomendação da informação. Conclui que as práticas de literacia informacional do Educamídia contribuem para o enfrentamento da desinformação e podem ser replicadas em outras pandemias.
Caminhos e descaminhos da política pública arquivística: o Ministério da Educação e a regulação do acervo acadêmico
Authors: Nascimento Adalson de Oliveira , Volpin Junior Marcos
Published: February 2025

Resumo: Este artigo tem por objetivo analisar o processo de regulação normativa do acervo acadêmico das Instituições de Ensino Superior, públicas e privadas, vinculadas ao Sistema Federal de Ensino. Tal processo é entendido como parte da política pública arquivística. A partir de 2013 o Ministério da Educação vem editando diversas portarias e notas técnicas regulando e orientando a produção e a guarda do chamado acervo acadêmico. Os documentos também foram objeto de um decreto federal. A metodologia da investigação apoiou-se no estudo das normas sobre o acervo acadêmico, esquadrinhadas à luz de conceitos arquivísticos e da legislação basilar da política pública arquivística brasileira. Como resultado da pesquisa, restou demonstrada a imprecisão sobre o conceito de acervo acadêmico ao longo do tempo. Também foi percebido o descompasso, ou a incongruência, entre os conceitos e os procedimentos definidos nas normas sobre tal conceito e a teoria arquivística, inserida na literatura do campo. Tal descompasso prejudicou a implantação da política pública arquivística voltada para as Instituições de Ensino Superior, visto que as normas estabelecidas pelo Ministério da Educação foram marcadas por lacunas, omissões, imprecisões e falhas conceituais.
Citizen Science in protected areas: best practices for project formulation and implementation
Authors: Pegler Gabriela Francisco , Ranieri Victor Eduardo Lima
Published: February 2025

Abstract Citizen science is recognized as a promising research approach. Conducted in protected areas, it can generate sound and useful data to inform decision-making that enhances inclusion and participation in their governance. While there are general guidelines guiding citizen science initiatives, little has been explored regarding best practices or lessons learned in their design and implementation in protected areas. Accordingly, the objective of this study is to describe citizen science projects in protected areas and to identify best practices in their design and implementation. A systematic literature review identified 45 best practices in 7 categories: Financing; Governance; Project Design; Methodology; Citizen Scientist Engagement; Dissemination of Findings and Evaluation. These practices can serve as an invaluable guide for coordinators of citizen science projects, strengthening the development of successful initiatives in protected areas.
Insights from a 3-year experience: depicting the flourishing of rheumatologists through entrustable professional activities
Authors: Chakr Rafael Mendonça da Silva , Kohem elaboração do manuscrito Charles Lubianca , Brenol Claiton Viegas , Xavier Ricardo Machado , Monticielo Odirlei André
Published: February 2025

ABSTRACT Introduction: The 14 entrustable professional activities (EPAs) approved by the American College of Rheumatology (ACR) were developed to be “the comprehensive set of tasks or responsibilities that any practicing rheumatologist should be capable of performing”. Our goal was to originally present and discuss the 3-year experience of regularly assessing rheumatology residents through ACR-approved EPAs. Experience report: In this case series, all first-year and second-year rheumatology residents were assessed every May and November (the residency program starts in March) via online anonymous forms. For the EPA assessment, preceptors chose 1 of 5 levels of entrustability. Unsupervised practice was defined as levels 4 (“I had to provide minor directions”) and 5 (“I did not need to provide directions for safe and independent care”) combined. Individual reports were discussed by the program supervisor in separate feedback meetings. Between 2021 and 2023, 276 EPA reports from 11 residents assessed by 10 preceptors were analyzed. The number of EPAs with over 90% of unsupervised practice rating in semesters 1, 2, 3 and 4 were, respectively, 1, 0, 2 and 11. Overall progression was statistically significant for 13 EPAs and greater between semesters 2 and 3. Feedback meetings with an agenda for residents and for the program supervisor contributed to individual improvement and training qualification. Discussion: Implementing EPAs in rheumatology residency was an opportunity to increase feedbacks and to qualify the program. The residents’ autonomy was practically nonexistent before the last assessment. Although a valuable formative instrument in residency, the entrustable professional activity-based assessment needs careful discussion before the adoption of cut-off values for summative purposes. Conclusions: Assessing rheumatology residents through the ACR-approved EPAs establishes a regular feedback culture, providing opportunity for graduate students’ improvement and program qualification. Unsupervised practice was mostly achieved by the end of the training and a greater increment coincided with the change in the year of residency.
Vivência no Serviço de Atendimento Móvel de Urgência durante o internato: um relato de experiência
Authors: Barbosa Guilherme Chacon Martinez Dastre , Siqueira Leonardo de Sousa
Published: February 2025

RESUMO Introdução: Este estudo tem como objetivo relatar as experiências vividas no Serviço de Atendimento Móvel de Urgência (SAMU) da cidade de Santos, no estado de São Paulo, no Brasil, pelos alunos do quinto ano de Medicina do Centro Universitário Lusíada durante o estágio no internato. Relato de experiência: Parte do tempo, os discentes ficavam na Central de Regulação, em um espaço reservado especificamente para a regulação médica, destinada para atender às ligações já triadas e direcionadas ao número 192. Em outros momentos, os acadêmicos tinham aulas teórico-práticas sobre os principais tópicos do atendimento pré-hospitalar e, quando possível e demandado, saíam de ambulância para prestar socorro às vítimas no município. Assim, os alunos tinham chance de lapidar suas ações na urgência e emergência com os pacientes, principalmente em uma abordagem mais sucinta e objetiva. Discussão: O serviço era diferente dos hospitais universitários ou do ambulatório de especialidades aos quais os estudantes estavam mais habituados, pois o atual meio era bem mais dinâmico, proporcionando aos discentes a chance de treinar suas habilidades de comunicação, liderança, manejo de crises, assim como relembrar e lapidar temas fundamentais para a profissão, seja de um médico generalista ou emergencista. Tudo isso ocorreu em um cenário acolhedor proporcionado pelos professores e trabalhadores do SAMU que ficaram supervisionando e maximizando o gosto dos acadêmicos por esses dias. Conclusão: As semanas passadas no serviço foram consideradas extremamente proveitosas pelos alunos, pois esse período proporcionou contemplações dos desafios que os trabalhadores do local enfrentam no dia a dia. Essa vivência também promoveu a percepção do SAMU como um possível vínculo empregatício na vida daqueles universitários em um futuro próximo, além de auxiliar no aprimoramento de saberes na área médica e no treinamento de soft skills dos que lá estavam.
Práticas integrativas e complementares: institucionalização, perspectivas e desafios para a formação
Authors: Santana Lauriane Martins , Assis Sheila Soares de , Araujo-Jorge Tania Cremonini de
Published: February 2025

Resumo A Política Nacional de Práticas Integrativas e Complementares do Sistema Único de Saúde é um conjunto de normas e diretrizes criadas para a implementação de tais práticas. O objetivo do estudo foi analisar a trajetória da referida política por meio de documentos oficiais, com enfoque nos desafios relacionados à formação em saúde e no impacto da hegemonia do modelo biomédico sobre a implementação de tais práticas. O estudo utilizou como instrumento de coleta e análise de dados a análise documental descritiva e a análise textual discursiva, respectivamente. Analisaram-se quatro documentos oficiais. Os resultados apontaram que o documento mais recente apresenta um detalhamento da trajetória de experiências profissionais com as práticas, justificando a oficialização da política. Identificamos a existência de um campo de saberes sobre as práticas anterior à regulamentação da política. Contudo, a abordagem sobre o ensino foi considerada incipiente. Os outros documentos analisados apresentaram somente uma descrição sobre as práticas inclusas na política. A abrangência da dimensão cultural no ensino em práticas integrativas e complementares pode contribuir para um olhar diversificado de tais práticas no Sistema Único de Saúde, de modo a romper com a exclusividade científica do modelo biomédico.
Novas tendências na amiloidose AA com envolvimento renal: experiência de um único centro
Authors: Marques Nídia , Oliveira-Silva Catarina , Pinho Ana , Nunes Ana Teresa , Sampaio Susana , Oliveira Ana , Tavares Isabel
Published: February 2025

Resumo Introdução: No noroeste de Portugal, a amiloidose AA foi relatada como a nefropatia amiloide mais frequente, embora não esteja claro se a incidência e desfechos da doença mudaram. Os autores analisaram alterações na epidemiologia, etiologias e desfechos de pacientes com amiloidose renal AA nos últimos 40 anos. Métodos: Estudo de coorte retrospectivo de centro único, envolvendo pacientes com diagnóstico de amiloidose AA comprovada por biópsia renal, realizado no noroeste de Portugal entre 1978 e 2019. Os pacientes foram agrupados em coortes de 14 anos baseadas no ano do diagnóstico (CA 1978–1991; CB 1992–2005; CC 2006–2019), com análises de evolução clínica e desfechos. Resultados: Incluímos 69 pacientes com amiloidose AA. A incidência da doença permaneceu estável em CA (64%) e CB (62,7%), em oposição à redução significativa na coorte mais recente (44%, p = 0,027). A idade média na apresentação aumentou em dez anos de CA para CC. No geral, infecções foram a principal causa de óbito, com aumento significativo ao longo do tempo (9,1% na CA para 76,9% na CC; p = 0,002). Não houve diferenças significativas de sobrevida global e renal entre as três coortes. Entretanto, pacientes na CC faleceram com idade mais avançada (61,4 anos) do que na CA (52,3 anos). Conclusão: A incidência de amiloidose AA tem diminuído nos últimos 40 anos. Em contrapartida, a idade de apresentação da nefropatia amiloide tem aumentado. Desfechos globais e renais não melhoraram, mas a expectativa de vida média aumentou, sugerindo progresso no manejo geral e no tratamento de suporte da patologia renal e subjacente.
Space-fed Array Variations of E-shape and U-slot cut Rectangular Microstrip Antennas using Modified Feed for Gain Enhancement
Authors: Deshmukh Amit A. , Parvez Adil , Chavali Venkata A. P.
Published: February 2025

Abstract Space-fed array comprising of E-shape or U-slot cut rectangular microstrip antennas using the modified feed designs are proposed for higher gain and wider bandwidth. Modified feed optimally illuminates the edge space-fed elements to achieve a maximum gain. Amongst the two space-fed array variations, 7 x 7 E-shape space-fed array, excited using the feed comprising of gap-coupled and stacked E-shape patches provides bandwidth and gain of 2.085 GHz (48.97%) and 18.5 dBi, respectively. The antenna exhibits broadside radiation pattern across the complete bandwidth. An experimental validation has been carried out for the simulated results that show a close agreement.
A Linha que nos Divide: o teatro negro racializando a branquitude
Authors: Cunha Amanda
Published: February 2025

Resumo: Um fator comum entre as pessoas brancas é a negação de que são sujeitos racializados, de modo que se utilizam da fragilidade e da inocência branca como estratégias para a proteção e usufruto do privilégio e da superioridade racial. Em contraponto, a arte decolonial é constituída por um conjunto de obras que ambicionam desvincular a produção artística dos não-europeus e não-brancos de uma suposta posição de inferioridade calcada na colonialidade. Assim, esta pesquisa buscou compreender como o teatro negro, entendido sob essa perspectiva decolonial, proporciona, ao espectador branco brasileiro e português, uma experiência racializadora. Os resultados permitiram explorar os entendimentos partilhados sobre a identidade branca, contribuindo para perceber o processo de racialização do espectador branco.
Venus in Fur: analysis of an artistic work in theater and cinema in the light of great time
Authors: Ribeiro João Vítor Zanato de Carvalho , Lodi Ana Claudia Balieiro
Published: February 2025

Abstract: This article aims to analyze the artistic work Venus in Fur through the theatrical play Venus in Fur, written by David Ives in 2010, and the French feature film Venus in Fur, directed by Roman Polanski in 2013. In this analysis, we seek to understand the dialogues established between the play and the film with previous artistic works, involving the historically built meanings about women and their social role, themes that permeate Venus in Fur. The theoretical-methodological perspective that underpins the proposed analysis is based on the studies of Bakhtin and the Bakhtin Circle, by understanding that artistic works are part of a long human discursive chain of great time, reflecting and refracting their own time, while responding to the past and being projected into the future. In turn, Venus in Fur promotes a major feast of renewal of meanings, extending its dialogue beyond its socio-historical context of circulation, reaching works from the past and other contexts, by situating the representation of women in art at the center of its discussion.
Ailton Krenak, person-poetry in performance
Authors: Silva Míriam , Dravet Florence
Published: February 2025

Abstract: The aim here is to read Krenak’s movement between worlds based on the observation of his performance in the media and institutional spaces, such as his entry into the Brazilian Academy of Letters. Through the essay and the notion of person-poetry, the anthropophagic methodology is used, with the critical and comprehensive reading of his work in relation to other references. A dialogical movement was made when thinking about the person-poetry based on Krenak’s philosophy and about the expression of his philosophy and political action. It is concluded that poetry in Krenak is an ontological condition, life itself that manifests in the body, in words and in political action and allows him to develop his performance.
Vestibulocochlear system and quality of life in musicians: a study on the effects of auditory exposure
Authors: Scheuer Magali , Pimentel Bianca Nunes , Martins Priscilla dos Santos , Moreira Hélinton Goulart , Santos Filha Valdete Alves Valentins dos
Published: February 2025

ABSTRACT Purpose To evaluate and compare the effects of sound exposure on the vestibulocochlear system and the quality of life among musicians. Methods Fifty-six individuals participated, including 28 musicians and 28 non-musicians, aged 18 to 45 years, of both genders. Participants underwent medical history assessment, basic audiological evaluation, vestibular evoked myogenic potential (VEMP), and exclusively, WHOQOL-Bref questionnaire. Results Professional and enthusiast musicians participated, showing increased auditory thresholds at 3 and 4 kHz frequencies and considerably satisfactory quality of life. There was significance in cervical VEMP latencies and the latency of the P15 wave in the left ocular VEMP of the study group compared to the control group. VEMP demonstrated larger waves bilaterally in men compared to women. Conclusion It was concluded that sound exposure, within tolerance limits in terms of time and intensity, was capable of providing auditory, vestibular, and quality of life benefits for musicians.
Script Voz – clinical case simulator of adults with behavioral dysphonia: planning and content creation
Authors: Nogueira Lorena Luiza Costa Rosa , Dias Sandro Renato , Almeida Anna Alice de Figueirêdo , Azevedo Renata Rangel , Gama Ana Cristina Côrtes
Published: February 2025

ABSTRACT Purpose To present the preliminary results of the development of a web platform aimed at training clinical reasoning aimed at the speech therapy approach to patients with behavioral dysphonia. Methods Methodological study that describes the tool development stages. The contents were defined by consensus from a panel of experts. The project will comply with the stages of planning, platform development, content creation, usability evaluation and user acceptance, redefinition of the tool and determination of charges. This article presents the processes and results of the first three stages. Results Called Script Voz, the web platform will initially include six clinical cases of behavioral dysphonia. The user can select one clinical case at a time, and must be guided sequentially through the assessment, diagnosis, and therapeutic planning stages of the case. To do so, you must choose the answer(s) you deem appropriate to each of the ten questions proposed for each clinical case. Procedure guides for assessment, diagnosis and therapeutic planning focused on clinical cases that will make up the tool are presented, highlighting their processes. Conclusion Script Voz will be freely accessible. The procedural guides provided here will guide data collection, manifestation diagnosis and therapeutic planning focused on the clinical cases that will make up the tool. The questions and feedback that will guide the user experience are still in the final stages of preparation. The tool will use real clinical cases and arguments anchored in the clinical reasoning of experienced professionals.
Meanings that occupational therapists attribute to narrative reasoning in the evaluation and intervention processes within critical care units
Authors: Hernández Lanas Oscar , Sepúlveda Carrasco Cristóbal , Gutiérrez Monclus Pamela
Published: February 2025

Abstract The article analyzes how a group of occupational therapists in a critical care unit gives meaning to the use of narrative reasoning in the evaluation and intervention of patients with critical illnesses. The research used a qualitative methodology with a phenomenological approach and non-probabilistic sampling. Information was collected through in-depth interviews with occupational therapists who work in a critical care unit. Dialogues from which texts emerged that were coded, identifying themes, categories and subcategories that allowed the interpretation of the collected data from a hermeneutic perspective. Among the most relevant results obtained, it can be shown that occupational therapists in a critical care unit attribute great importance to the implementation of narrative reasoning and strategies that involve the creation and telling of stories in the evaluation, intervention, and recovery processes of patients with critical illnesses. This is because narrative reasoning facilitates the therapeutic process by allowing occupational therapists to understand the meaning of the illness and the influence of the environment, grounding the therapeutic actions used in the evaluation and intervention within these units. In conclusion, it is possible to establish that the application of narrative reasoning and its two branches, storytelling and story creation, are essential for the evaluation and intervention of critical patients. This acknowledges the patient's experience, allowing for the expression of everyday life and reducing socio-cultural barriers in a biomedical context.
ANÁLISE DE BIG DATA, INTELIGÊNCIA ARTIFICIAL, AMBIDESTRIA E GESTÃO DE CADEIA DE SUPRIMENTOS VERDE: IMPLICAÇÕES NA ECONOMIA RESPONSÁVEL
Authors: Wang Shanshan , Jia Chenge , Khan Asif , Khan Naila Habib , Hsieh Chia-Hung , Hung Chung-Wen , Chen Shih-Chih
Published: February 2025

RESUMO As empresas reconhecem o papel crucial dos dados no mercado atual, com tecnologias de sustentabilidade cada vez mais adotadas para vantagens competitivas. A análise de Big Data, inteligência artificial e a gestão da cadeia de suprimentos verde (GSCM) são estratégias prevalentes para promover a sustentabilidade. A pesquisa, envolvendo 220 funcionários do setor manufatureiro taiwanês, revela impactos significativos da análise de Big Data e inteligência artificial na gestão da cadeia de suprimentos verde e na ambidestria. Além disso, a ambidestria da cadeia de suprimentos influencia significativamente a gestão da cadeia de suprimentos verde e medeia a relação entre análise de Big Data, inteligência artificial e gestão da cadeia de suprimentos verde. Este estudo destaca a importância crítica da cadeia de suprimentos verde na economia responsável, esclarecendo como alavancar inteligência artificial e Big Data aprimora a ambidestria da cadeia de suprimentos, fortalecendo práticas sustentáveis sem alterações detectáveis.
Justiça reprodutiva nos debates sobre a esterilização de mulheres e sobre o vírus Zika
Authors: Carvalho Layla Pedreira , Elias Maria Ligia Ganacim Granado Rodrigues
Published: February 2025

Resumo O objetivo geral deste artigo é discutir a ideia de justiça reprodutiva como uma referência de cumprimento aos direitos humanos das mulheres, relacionando-a com os casos da CPMI de Esterilização em Massa e da Ação do Zika (ADI 5581). Afora uma reconstrução do debate acadêmico em torno dos conceitos de direitos sexuais e reprodutivos, dos direitos humanos das mulheres e de justiça reprodutiva, pretendemos mobilizar a noção de justiça reprodutiva como instrumento analítico, para além de uma perspectiva normativa. O conceito de justiça reprodutiva é central porque, se o aborto é um tema fundamental para os feminismos, a discussão sobre as possibilidades de ser mãe é igualmente importante para a perspectiva feminista. Trata-se de uma discussão de natureza qualitativa, informada por uma perspectiva feminista de pesquisa bibliográfica e análise documental.
In vitro susceptibility pattern of Rhodococcus equi isolated from patients to antimicrobials recommended exclusively to humans, to domestic animals and to both
Authors: Ribeiro Nícolas Garcia , Silva Paulo da , de Lima Paz Patrick Júnior , Arabe Filho Marcelo Fagali , Listoni Fernando Paganini , Listoni Evandro Paganini , Panegossi Letícia Colin , Ribeiro Márcio Garcia
Published: February 2025

ABSTRACT Rhodococcus equi is an opportunistic soil-borne bacterium that is eliminated in feces of multi-host animals. An increase in multidrug-resistant R. equi isolates has been reported in humans and domestic animals, and it has been hypothesized that the treatment of R. equi in foals could increase the selective pressure on multidrug-resistant isolates and favor human infections by resistant isolates. We investigated the in vitro antimicrobial susceptibility/resistance of 41 R. equi strains from humans, which were isolated from patients with pulmonary signs, using 19 antimicrobials from 10 distinct classes, recommended exclusively to humans, recommended exclusively to domestic animals and used in both. All isolates were subjected to mass spectrometry and identified as R. equi. Among the antimicrobials used exclusively in humans, tigecycline and vancomycin showed 100% efficacy. Amikacin, amoxicillin/clavulanic acid, imipenem, levofloxacin, clarithromycin, rifampin, ciprofloxacin, and gentamicin, used in both humans and animals, revealed high efficacy (97–100%). Conversely, a higher frequency of isolates was resistant to penicillin (87.8%) and trimethoprim/sulfamethoxazole (43.9%), which are used in both humans and animals. Among the antimicrobials used only in animals, isolates were resistant to florfenicol (46.4%), ceftiofur (17.1%), and enrofloxacin (2.5%). Multidrug resistance was observed in 34% of isolates. The identification of drug-resistant R. equi isolated from humans used exclusively in animals is circumstantial evidence of the pathogen transmission from domestic animals to humans. This study contributes to the molecular identification of Rhodococcus species from humans and to the epidemiological vigilance of the multidrug-resistant isolates.
Higher T-bet and IFN-γ expression in advanced chagasic megaesophagus indicates Th1 response in the chronic phase
Authors: Ribeiro Betânia Maria , Helmo Fernanda Rodrigues , Rodrigues Denise Bertulucci Rocha , Silva Marcos Vinícius da , Rodrigues Jr Virmondes
Published: February 2025

ABSTRACT Myenteric plexus injury is responsible for the morpho-functional alterations observed in chagasic megaesophagus (CME). The inflammatory response, characterized by elevated synthesis of IFN-γ, TNF-α, and IL-4, contributes to the persistence of parasitism and inflammation. This study assessed the mRNA expression of cytokines, transcription factors, and metalloproteases in subjects with CME. From 2011 to 2017, esophageal samples were collected from 54 subjects with CME (38 advanced and 16 nonadvanced) and eight subjects with idiopathic megaesophagus (IME). The quantitative mRNA expression of TNF-α, IFN-γ, IL-4, IL-10, IL-17, IL-22, IL-23, IL-27, T-bet, ROR-γT, GATA-3, MMP-1, MMP-2, and TIMP-3 genes was analyzed using SYBR Green systems. T-bet expression was significantly higher in the CME group compared to the IME group and the GATA-3 and ROR-γT expression in the CME group, corroborating the higher IFN-γ expression observed in subjects with advanced CME. The increased T-bet and IFN-γ expression in advanced CME reflects the maintenance of a Th1 response in situ and the morpho-functional changes seen in the organ.
Detection of Trypanosoma cruzi in white-eared opossums (Didelphis albiventris) from Canoinhas, Santa Catarina State, Brazil
Authors: Pontarolo Giane Helenita , Pedrassani Daniela , Kühl Luís Felipe , Campos Monique Paiva , Tirado Thais Cristina , Figueiredo Fabiano Borges , Vieira Thállitha Samih Wischral Jayme , Calchi Ana Cláudia , André Marcos Rogério , Vieira Rafael Felipe da Costa , Barros Filho Ivan Roque de
Published: February 2025

Abstract Opossums are synanthropic animals that participate in the zoonotic transmission cycles. Chagas disease, a neglected tropical disease caused by Trypanosoma cruzi, affects many domestic and wild animals and humans worldwide. This study aimed to determine the occurrence of T. cruzi in free-ranging opossums in Canoinhas, Santa Catarina, Brazil. Fifty opossums (Didelphis albiventris) (33 captured and 17 road-killed) were evaluated using Nested-PCR assay. All tissue samples were negative (0/17). Eight of the 33 (24.24%; 95% CI:11.94–40,89%) blood samples were positive for T. cruzi. No significant associations were found between the sex (male/ female, p = 0.423), the trap area (rural/urban, p = 0.163), and positivity for T. cruzi in opossum blood samples. All samples showed 100% identity with T. cruzi (KF788250) isolated from Panstrongylus megistus in São Paulo, Brazil. The phylogenetic analysis model allocated all sequences obtained from D. albiventris to the large TcI clade of T. cruzi. This study provides the first record of T. cruzi in white-eared opossums in Canoinhas, Santa Catarina, southern Brazil.
Genotype-Based Molecular Mechanisms in Alport Syndrome
Authors: Caparali Emine Bilge , De Gregorio Vanessa , Barua Moumita
Published: February 2025

Alport syndrome (AS) is an inherited disorder characterized by kidney disease, sensorineural hearing loss and ocular abnormalities. AS is caused by pathogenic variants in COL4A3, COL4A4 or COL4A5, which encode the α3, α4 and α5 chains of type IV collagen that forms a heterotrimer expressed in the glomerular basement membrane. Knowledge of its genetic basis has informed the development of different models in dogs, mice and rat that reflect its autosomal and X-linked inheritance patterns as well as different mutation types, including protein truncating and missense variants. A key difference between these two types is the synthesis of α3α4α5(IV), which is not made in autosomal AS (2 pathogenic variants in trans or biallelic) or males with X-linked Alport syndrome due to protein truncating variants. By contrast, α3α4α5(IV) is synthesized in AS due to missense variants. For missense variants, in vitro studies suggest that these cause impaired type IV collagen trafficking and ER stress. For protein truncating variants, knockout models suggest that persistence of an immature α1α1α2(IV) network is associated with biomechanical strain, which activates endothelin-A receptors leading to mesangial filopodia formation. Moreoever, studies suggest that activation of collagen receptors integrins and DDR1 play a role in disease propagation. In this review, we provide an overview of how these genotype-phenotype-mechanisms are key for a precision medicine-based approach in the future.
The Role of the Digital in Roman Archaeology
Authors: Crizbasan Cristina , Mitrofan Dragos
Published: February 2025

The editorial of the seventh volume of the Theoretical Roman Archaeology Journal explores the intertwining relationships between digital platforms and Roman archaeology. When faced with powerful digital tools, misinformation may be dangerously amplified. This editorial addresses the increasing influence of social media, particularly TikTok, in disseminating archaeological information to a wider public. It examines the role of misinformation, exemplified by the viral claim that ‘Rome does not exist’, and raises questions about how archaeologists can engage with such platforms to combat misunderstandings while promoting informed discussions of complex topics like identity and cultural diversity in the Roman world. As a case study, we use the 2023 Theoretical Roman Archaeology Conference (TRAC) to reflect on the reception of digital tools for conference hosting post-pandemic. Held for the first time in a hybrid format at the University of Exeter, TRAC 2023 demonstrated the potential of digital tools, particularly Gather.town, to broaden participation and enhance accessibility for a global audience. In the end, we call for greater awareness and responsibility in the digital dissemination of archaeological knowledge, balancing the opportunities for broader engagement with the need for critical reflection.
Developments in Chinese Chipmaking
Authors: Caines Colin C. , Jeon Sharon , Quijano Cheyenne
Published: February 2025

The global semiconductor industry has become a key source of global economic and geopolitical risks. Due to a combination of huge fixed costs, highly specialized human capital, and a high degree of geographic concentration at different stages of production, chipmaking exhibits extremely low substitutability throughout the value chain. Consequently, the industry is vulnerable to supply chain shocks, which, given the role of semiconductors as a necessary input to a huge array of manufactured goods (figure 1), can have large and persistent global effects. Moreover, chips are also viewed as crucial to developing frontier technologies such as artificial intelligence and are increasingly critical to national security.