bluuebunny/crossref_metadata_2025 huggingface dataset:
Autonomous bi-pronominal distributive constructions in Russian
Authors: Apresjan Valentina
Published: August 2022

The paper is devoted to one type of Russian distributive constructions with two interrogative pronouns, such as kto kuda lit. “who where”, kto o čëm lit. “who about what”, kogda kak lit. “when how”, which bear the meaning ‘diff erent Xs are characterized by diff erent Ys’. We discovered that the constructions without a predicate in the right context form a special type, which diff ers both from indirect distributive questions and quasi-relatives in their semantic, pragmatic, syntactic, and communicative properties. Based on corpus data, we show their historical development and modern usage, as well as describe the most frequent lexical variables which fi ll the construction. The conclusion is that the frequency, syntactic features, and degree of idiomatization have their own semantic, communicative, and pragmatic grounds.
Alimentação Em Fim De Vida: Qual O Caminho?
Authors: Alves Patrícia Vinheiras , Oliveira Célia Simão , Basto Marta Lima
Published: July 2022

A alimentação está presente de forma permanente na nossa vida, sendo necessária por questões de sobrevivência e pautada por aspetos psicológicos, socioculturais e espirituais. Devido ao avançar da doença e às alterações alimentares que surgem, em fim de vida, a alimentação torna-se ainda mais complexa e é, muitas vezes, um tema de controvérsia entre a pessoa, a família e os profissionais de saúde, nomeadamente o enfermeiro, que está presente em todos os momentos relacionados com a alimentação. As alterações alimentares induzem, muitas vezes, ao questionamento dos envolvidos sobre as intervenções mais adequadas e ponderando o uso da alimentação e hidratação artificiais. O presente artigo apresenta uma análise crítica baseada na revisão da literatura, acerca das alterações alimentares da pessoa em fim de vida e da controvérsia da alimentação e hidratação artificiais nesta fase da vida, espelhando a complexidade deste fenómeno. Conclui-se que a alimentação em fim de vida deve ser um processo individualizado com a pessoa e maximizando o seu conforto.
Manos al Ambiente aprendizaje basado en proyectos. Cursos: Ética y Profesión, Bioética y Epistemología
Authors: Arcos Villota Juan Pablo
Published: August 2022

Manos al Ambiente es una experiencia que se ha venido consolidando desde hace cinco años con los estudiantes y con alianzas institucionales; tiene como lema: “Piensa, siente y estás sembrando vida”. Este proyecto busca acciones concretas para la recuperación de los lugares hídricos que están sumergidos en las cuencas hidrográficas del municipio de Pasto, especialmente en el cinturón oriental. Para responder a esta iniciativa, se realiza una serie de acciones significativas, entre ellas: limpieza y mantenimiento de los cauces y cursos de las quebradas, siembra de árboles y acompañamiento formativo a los habitantes del sector por parte de los estudiantes.
Foro de filosofía estudiantil, aprendizaje basado en proyectos. Curso: Pensamiento Filosófico
Authors: Trujillo Rodríguez Alberto Vianney
Published: August 2022

El foro de filosofía estudiantil es una estrategia pedagógica que apunta a fortalecer el pensamiento crítico de los estudiantes de la universidad, especialmente los matriculados en el espacio académico de Pensamiento Filosófico, quienes hacen un ejercicio de lectura y análisis del contexto y la realidad en confrontación con textos filosóficos, que permiten comprender un mismo fenómeno desde distintas miradas, ya que suscitan el diálogo y la discusión. Es “la verdadera racionalidad, abierta por naturaleza, dialoga con una realidad que se le resiste” (Morín, 1999, p. 7).
Generación compasiva aprendizaje basado en proyectos. Curso: Humanismo Cristiano
Authors: Chamorro Guerrero Eyner Fabián
Published: August 2022

El Humanismo Cristiano, curso de formación institucional de la Universidad Mariana para los programas de pregrado y posgrado, busca incentivar en los estudiantes los fundamentos y valores humano-cristianos marianos y franciscanos de manera experiencial, acordes con los principios misionales institucionales de carácter católico de la formación profesional. Para tal propósito, desde hace cinco años, los docentes vienen innovando estrategias de formación fundamentadas en el aprendizaje basado en proyectos, considerando que la formación no puede limitarse a la fundamentación conceptual en el aula, con limitadas posibilidades de praxis experiencial formativa, sino que va más allá; propende por la praxeología pedagógica para la plena vivencia de los valores que promueve. Pues, en la era de la formación positivista y pragmatista de la ciencia y la tecnología, las concepciones minimizadas de aporte de las humanidades y las competencias blandas, posibles acepciones de relleno o costura en la malla curricular, frente a una eminentemente crisis humanista de la cultura moderna, urge hacer efectivo los retos misionales evangélicos que tiene la universidad en el siglo XXI, aludiendo a la tarea pertinente de la responsabilidad social universitaria, humanizando las ciencias.
Effects of lumbar joint mobilization on trunk function, postural balance, and gait in patients with chronic stroke: A randomized pilot study
Authors: Choi Wonjae , Lee Jieun , Lee Seungwon
Published: August 2022

BACKGROUND: Patients with stroke have hypomobility in the facet joint of affected side. Lumbar joint mobilization could be used to maintain function and mobility of the joints. OBJECTIVE: This study aimed to investigate the effects of lumbar joint mobilization on trunk function, postural balance, and gait in patients with stroke. METHODS: Thirty patients with stroke were randomly assigned to two groups. Lumbar joint mobilization was provided for 15 min, 5 times a week for 6 weeks to patients who were allocated into the experimental group. Patients who were allocated into the control group received a sham intervention. Trunk function (trunk impairment scale), postural balance (weight distribution, Berg balance scale, and timed up and go test), and walking (10 m walk test, functional gait assessment, step length, and stride length) were evaluated before and after the experiment for all the patients. RESULTS: Lumbar joint mobilization significantly improved trunk function, postural balance, and gait compared with pre-test values in the experimental group (P< 0.05). Significant differences were seen in trunk function, postural balance, and walking between the two groups (P< 0.05). CONCLUSION: Lumbar joint mobilization might be an effective intervention for trunk function, postural balance, and walking in patients with stroke.
Prognostic significance of programmed death-1 and programmed death ligand-1 proteins in breast cancer
Authors: Tahir Imtiaz Mahmood , Rauf Abdur , Mehboob Huma , Sadaf Samia , Alam Muhammad Shaiful , Kalsoom Fadia , Bouyahya Abdelhakim , El Allam Aicha , El Omari Nasreddine , Bakrim Saad , Akram Muhammad , Raza Syed Kashif , Emran Talha Bin , Mabkhot Yahia N. , Zengin Gokhan , Derkho Marina , Natalya Suray , Shariati Mohammad Ali
Published: August 2022

In numerous studies related to tumor prognosis, programmed death-ligand 1 (PD-L1) has been identified as a biomarker. This work aimed to determine the prognostic importance of PD-L1 in breast cancer. We searched electronic databases such as PubMed, Google scholar, home pages of publishing groups, medical, clinical, and pharmaceutical sciences journals, as well as other relevant sources to discover the importance of PD-1 and PD-L1 expression in breast cancer therapies and also recurrence. The keywords used in this search were autoimmunity, programmed cell death, PD-L1 or PD-1, and breast cancer. Our inclusion criteria included studies showing the synergy between the expression of PD-L1 and PD-1 in primary breast cancers as prognostic markers and this research was limited to humans only. We included review articles, original research, letters to the editor, case reports, and short communications in our study, published in English. We focused our work on PD-L1 mRNA expression in breast cancer cell lines. PD-L1 expression has been decisively demonstrated to be a high-risk factor for breast cancer with a bad prognosis.
Differential effects of dynamic and ballistic stretching on contralateral lower limb flexibility
Authors: Inoue Taisei , Nagano Katsuhito
Published: August 2022

BACKGROUND:

Dynamic stretching (DS) and ballistic stretching (BS) are similar stretching methods, but the differences between them are unclear.

OBJECTIVE:

To examine the immediate effects of unilateral hamstring DS and BS on straight leg raise (SLR), knee flexion range of motion (KF-ROM), and KF and knee extension maximal isokinetic peak torque (KF-MIPT and KE-MIPT) of the bilateral limbs.

METHODS:

Twelve healthy adult men performed four sets of 2 min each of non-stretching, DS, or BS of the right lower extremity. Bilateral SLR, KF-ROM, KF-MIPT, and KE-MIPT were measured pre- and post-intervention; a three-way (intervention [Formula: see text] limb [Formula: see text] time) repeated-measures analysis of variance (ANOVA) was used.

RESULTS:

The SLR of the stretched limb ([Formula: see text] 0.01) was higher with DS than that pre-intervention. SLR ([Formula: see text] 0.01) and KF-ROM ([Formula: see text] 0.05) of the stretched limb and SLR ([Formula: see text] 0.05) and KF-ROM ([Formula: see text] 0.05) of the contralateral limb were higher with BS than those pre-intervention. There was no significant main effect or interaction between KF-MIPT and KE-MIPT.

CONCLUSION:

DS and BS had slightly different effects on ROM, and neither affected muscle strength; thus, combining the techniques during warm-up might be helpful.
Lifestyle and Cognitive Decline in Community-Dwelling Stroke Survivors
Authors: Dhana Klodian , Aggarwal Neelum T. , Beck Todd , Holland Thomas M. , Dhana Anisa , Cherian Laurel J. , Desai Pankaja , Evans Denis A. , Rajan Kumar B.
Published: August 2022

Background: Patients with stroke are at a higher risk of cognitive impairment and Alzheimer’s disease dementia. Objective: To quantify the role of lifestyle pre-stroke, post-stroke, and changes in lifestyle before and after stroke with cognitive decline in community-dwelling stroke survivors. Methods: Utilizing data from the Chicago Health and Aging Project, a population-based cohort study, we studied 1,078 individuals with stroke (662 incident and 416 prevalent) who underwent cognitive testing during the study period. A healthy lifestyle score was defined by scoring four behaviors: non-smoking, exercising, being cognitively active, and having a high-quality diet. The global cognitive score was derived from a comprehensive battery of 4 standardized tests. Results: The mean age at incident stroke was 78.2 years, and 60.1% were women. A healthy lifestyle pre-incident stroke was associated with a slower rate of cognitive decline after stroke. Participants with 3–4 healthy lifestyle factors pre-incident stroke had a slower cognitive decline after stroke by 0.046 units/year (95% CI 0.010, 0.083), or 47.7% slower, than participants with 0–1 healthy lifestyle factor. Lifestyle score post-prevalent stroke was not associated with cognitive decline. Changes in lifestyle behaviors from pre- to post-incident stroke were related to cognitive decline after stroke. Individuals who deteriorated their lifestyle quality after stroke had a faster cognitive decline by 0.051 units/year (β –0.051, 95% CI –0.090, –0.012) than participants with no change in lifestyle score. Conclusion: A healthy lifestyle pre-stroke was associated with a slower rate of cognitive decline in stroke survivors, highlighting the importance of primary prevention. After the stroke, changes in lifestyle behaviors may influence the cognitive abilities of older adults as they age.
Stakeholder Insights in Alzheimer’s Disease: Natural Language Processing of Social Media Conversations
Authors: Tahami Monfared Amir Abbas , Stern Yaakov , Doogan Stephen , Irizarry Michael , Zhang Quanwu
Published: August 2022

Background: Social media data may be especially effective for studying diseases associated with high stigma, such as Alzheimer’s disease (AD). Objective: We primarily aimed to identify issues/challenges experienced by patients with AD using natural language processing (NLP) of social media posts. Methods: We searched 130 public social media sources between January 1998 and December 2021 for AD stakeholder social media posts using NLP to identify issues/challenges experienced by patients with AD. Issues/challenges identified by ≥10% of any AD stakeholder type were described. Illustrative posts were selected for qualitative review. Secondarily, issues/challenges were organized into a conceptual AD identification framework (ADIF) and representation of ADIF categories within clinical instruments was assessed. Results: We analyzed 1,859,077 social media posts from 30,341 AD stakeholders (21,011 caregivers; 7,440 clinicians; 1,890 patients). The most common issues/challenges were Worry/anxiety (34.2%), Pain (33%), Malaise (28.7%), Confusional state (27.1%), and Falls (23.9%). Patients reported a markedly higher volume of issues/challenges than other stakeholders. Patient posts reflected the broader scope of patient burden, caregiver posts captured both patient and caregiver burden, and clinician posts tended to be targeted. Less than 5% of the high frequency issues/challenges were in the “function and independence” and “social and relational well-being” categories of the ADIF, suggesting these issues/challenges may be difficult to capture. No single clinical instrument covered all ADIF categories; “social and relational well-being” was least represented. Conclusion: NLP of AD stakeholder social media data revealed a broad spectrum of real-world insights regarding patient burden.
A Deep-DrpXML and IAG-GWO based CHST fostered blockchain technology for secured dynamic optimal routing for wireless sensor networks
Authors: Anitha R. , Bapu B.R. Tapas
Published: August 2022

In wireless sensor network (WSN), routing is one of the substantial maneuvers for distributing data packets to the base station. But malevolent node outbreaks will happen during routing process, which exaggerate the wireless sensor network operations. Therefore, a secure routing protocol is required, which safeguards the routing fortification and the wireless sensor network effectiveness. The existing routing protocol is dynamically volatile during real time instances, and it is very hard to recognize the unsecured routing node performances. In this manuscript, a Deep Dropout extreme Machine learning optimized Improved Alpha-Guided Grey Wolf based Crypto Hash Signature Token fostered Blockchain Technology is proposed for secure dynamic optimal routing in Wireless Sensor Networks (SDOR-DEML-IAgGWO-CHS-BWSN). In this, Crypto Hash signature (CHS) token are generated for flow accesses with a secret key owned by each routing sensor node and it also offers an optimal path for data transmission. Then the secured dynamic optimal routing information is delivered through the proposed Blockchain based wireless sensor network platform with the help of Deep Dropout Extreme Machine learning optimized Improved Alpha-Guided Grey Wolf routing algorithm. Then the proposed method is simulated using the NS-2 (Network Simulator) tool. The simulation performance of the proposed SDOR-DEML-IAgGWO-CHS-BWSN method provide 76.26%, 65.57%, 60.85%, 48.99% and 42.9% lower delay during 30% malicious routing environment, 73.06%, 63.82%, 59.25%, 44.79% and 38.84% lower delay during 60% malicious routing environment is compared with the existing methods.
Management of Sleep Disturbances in Parkinson’s Disease
Authors: Schütz Lukas , Sixel-Döring Friederike , Hermann Wiebke
Published: August 2022

Parkinson’s disease (PD) is defined by its motor symptoms rigidity, tremor, and akinesia. However, non-motor symptoms, particularly autonomic disorders and sleep disturbances, occur frequently in PD causing equivalent or even greater discomfort than motor symptoms effectively decreasing quality of life in patients and caregivers. Most common sleep disturbances in PD are insomnia, sleep disordered breathing, excessive daytime sleepiness, REM sleep behavior disorder, and sleep-related movement disorders such as restless legs syndrome. Despite their high prevalence, therapeutic options in the in- and outpatient setting are limited, partly due to lack of scientific evidence. The importance of sleep disturbances in neurodegenerative diseases has been further emphasized by recent evidence indicating a bidirectional relationship between neurodegeneration and sleep. A more profound insight into the underlying pathophysiological mechanisms intertwining sleep and neurodegeneration might lead to unique and individually tailored disease modifying or even neuroprotective therapeutic options in the long run. Therefore, current evidence concerning the management of sleep disturbances in PD will be discussed with the aim of providing a substantiated scaffolding for clinical decisions in long-term PD therapy.
UNICEF remote learning readiness index: A composite indicator to assess resilience of education sector against crises and emergencies
Authors: Avanesian Garen , Mizunoya Suguru , Delamonica Enrique
Published: August 2022

The paper presents the methodological work behind production of the UNICEF Remote Learning Readiness Index, a composite indicator to assess the resilience of education sector against crises and emergencies. The index is composed of demand-side factors, such as readiness for remote learning observed at the household level, supply-side factors that are approximated by the education policy response of the governments to the COVID-19 outbreak, and systemic factors that refer to the overall preparedness of education sector to crises and emergencies. The major novelty of the adopted methodological approach to measure how national education systems can ensure every child learns refers to the emphasis put by the index on the weakest parts of the system. The adopted “weakest link” approach allows the index to guide policy-making and be sensitive to a country improvement in time. The work also accentuates the importance of the index application beyond the COVID-19 pandemic, as disruptions to education supply are not unique to the current health crisis and can happen due to the conflicts, natural or men-made disasters, or other factors.
The ILO nowcasting model: Using high-frequency data to track the impact of the COVID-19 pandemic on labour markets1
Authors: Gomis Roger , Carrillo Paloma , Kapsos Steven , Kühn Stefan , Mahajan Avichal
Published: August 2022

The impact of the COVID-19 pandemic resulted in unprecedented labour market disruption, triggering the most severe global labour market crisis on record. The speed and depth of the crisis rendered labour force survey data unable to provide timely information. The ILO nowcasting model was designed to track the disruption in the world of work caused by the pandemic. This required: 1) filling data gaps, 2) increasing the timeliness of available data, and 3) focusing on an indicator that captured well the pandemic disruption: hours worked. The estimates obtained from the ILO nowcasting model have become the backbone of the empirical strategy behind the ILO Monitor on the World of Work publication series. The latest estimates corroborate that the pandemic induced very large declines in hours worked at an unprecedented speed. Furthermore, the recovery process has stalled, driven by a stagnant recovery in developing economies. The country-level input data and estimates of the ILO nowcasting model allow for complementary analysis, which was published in the ILO Monitor. The topics included the effects of COVID-19 testing and tracing, fiscal stimulus, and vaccination on labour market outcomes.
Prevalence of symptoms of work-related musculoskeletal disorders and their associated factors: A cross-sectional survey of sewing machine operators in Sindh, Pakistan
Authors: Brohi Saman , Khokhar Rasham , Marriam Paras , Rathor Ameeta , Memon Aamir Raoof
Published: August 2022

BACKGROUND: The nature of the work of sewing machine operators predisposes them to a wide variety of symptoms of musculoskeletal disorders and obesity. However, there is a paucity of studies on the prevalence and associated factors for symptoms of work-related musculoskeletal disorders (WMSDs) among this occupational group. OBJECTIVES: This study aimed to determine the prevalence of symptoms of WMSDs and their association with personal and occupational factors and body mass index (BMI) among sewing machine operators of Sindh province in Pakistan. METHODS: This cross-sectional study was conducted on male sewing machine operators in two major cities (i.e., Hyderabad and Nawabshah) of Sindh province in Pakistan. Obesity was determined through the BMI cutoff values for Asians. Standardized Nordic Musculoskeletal Questionnaire and Numeric Rating Scale were used. Data analysis was performed using SPSS v20. RESULTS: Of the 200 participants, 91% participants had symptoms of WMSDs in the past 12 months. Most (41.5%) participants reported pain and discomfort during the last 12 months in the lower back region. Symptoms of WMSDs in the lower back region had a significant positive association with working days/week (r = .196 p = .005). Symptoms of WMSDs in the ankle/feet region had a significant positive association with age (r = .246 p = .001) and work experience (r = .276 p = .001). CONCLUSIONS: Prevalence of symptoms of work-related musculoskeletal disorders is high among sewing machine operators of Sindh province in Pakistan, with significant associations between personal and occupational factors.
Evaluation of a workplace alcohol prevention program targeted on managers’ inclination to initiate early alcohol intervention
Authors: Elling Devy L. , Almquist Ylva B. , Wennberg Peter , Sundqvist Kristina
Published: August 2022

BACKGROUND: Alcohol interventions targeting the adult population are often conducted in healthcare settings, while preventive interventions often target adolescents or young adults. The general working population is often overlooked. A workplace-based intervention, consisting of development and implementation of an organizational alcohol policy, and skills development training for managers (APMaT) was carried out in order to prevent and reduce alcohol-related harms by identifying hazardous consumers at an early stage. OBJECTIVE: This study aims to evaluate APMaT by focusing on managers’ inclination to initiate early alcohol intervention. METHODS: In a cluster randomized design, data were obtained from 187 managers (control: n = 70; intervention: n = 117). Inclination to initiate early alcohol intervention was measured using three items on a 5-point Likert scale ranging from 1 (strongly disagree) to 5 (strongly agree). Changes in managers’ inclination to intervene were analyzed by applying multilevel ordered logistic regression. Predictors included in the model were group (control vs. intervention), time (baseline vs. 12-month follow-up), and the multiplicative interaction term (group×time). RESULTS: Significant increase in inclination to intervene against hazardous alcohol consumption among managers in the intervention group compared to managers in the control group was observed. Specifically, a 50% increase of confidence to initiate an intervention was observed among managers in the intervention group. CONCLUSIONS: APMaT seems effective to increase managers’ inclination to intervene early against hazardous consumption in the workplace. The effectiveness of APMaT at the employee level should be explored in prospective studies.
Returning to work and the impact of post COVID-19 condition: A systematic review
Authors: Gualano Maria Rosaria , Rossi Maria Francesca , Borrelli Ivan , Santoro Paolo Emilio , Amantea Carlotta , Daniele Alessandra , Tumminello Antonio , Moscato Umberto
Published: August 2022

BACKGROUND: The COVID-19 pandemic is still ongoing, with rapidly increasing cases all over the world, and the emerging issue of post COVID-19 (or Long COVID-19) condition is impacting the occupational world. OBJECTIVE: The aim of this systematic review was to evaluate the impact of lasting COVID-19 symptoms or disability on the working population upon their return to employment. METHODS: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statements we performed a systematic review in December 2021, screening three databases (PubMed, ISI Web of Knowledge, Scopus), for articles investigating return to work in patients that were previously hospitalized due to COVID-19. A hand-searched was then performed through the references of the included systematic review. A quality assessment was performed on the included studies. RESULTS: Out of the 263 articles found through the initial search, 11 studies were included in this systematic review. The selected studies were divided based on follow-up time, in two months follow-up, follow-up between two and six months, and six months follow-up. All the studies highlighted an important impact of post COVID-19 condition in returning to work after being hospitalized, with differences based on follow-up time, home Country and mean/median age of the sample considered. CONCLUSIONS: This review highlighted post COVID-19 condition as a rising problem in occupational medicine, with consequences on workers’ quality of life and productivity. The role of occupational physicians could be essential in applying limitations to work duties or hours and facilitating the return to employment in workers with a post COVID-19 condition.
CARTOGRAFANDO OS DIREITOS HUMANOS EM CURITIBA: DA NORMATIZAÇÃO ÀS PRÁTICAS EM EDUCAÇÃO
Authors: Barszcz Milaine Alves , Cunha Cláudia Madruga
Published: July 2022

Neste artigo retoma-se alguns acontecimentos do século XX para pensar o contexto de surgimento dos Direitos Humanos e da filosofia pós-estruturalista de DELEUZE; GUATTARI (1995a; 1995b; 2014). Essa retomada permite localizar o olhar com o qual observa-se as possiblidades de uma experiência de Educação em Direitos Humanos, através da análise cartográfica (KATRUP, PASSOS, 2013), realizado em uma escola básica de Curitiba. Trata-se de uma análise em uma cartografia que se organizou em três movimentos: de territorialização, que situa os processos de institucionalização das relações entre a educação e os Direitos Humanos;  de desterritorialização, quando seleciona alguns propostos por intelectuais que avançam a perspectiva deleuziana-guattariana, como é o caso de educação menor (GALLO, 2008) e biopotência (GUATTARI; RONILK, 2006); por fim, em um retorno que não é ao mesmo, de reterritorialização, o qual apresenta a análise dos planos de ação para a Educação em Direitos Humanos, elaborados entre os anos de 2017 e  2019 propostos pela escola.
DESAFIOS PARA UMA EDUCAÇÃO EM E PARA OS DIREITOS HUMANOS: ANOTAÇÕES A PARTIR DE UMA EXPERIÊNCIA NA UFGD
Authors: Arruda Rodolfo , Faisting André
Published: July 2022

O objetivo é desenvolver uma reflexão sobre os desafios que envolvem o ensino e a promoção dos direitos humanos a partir da experiência da disciplina Educação em Direitos Humanos na UFGD, no período entre 2017 - 2020. A análise buscou identificar, por meio de materiais de experiências pedagógicas, os conteúdos curriculares ofertados, as abordagens de ensino desenvolvidas, bem como desafios e limites para a realização das diretrizes de área da EDH. Para desenvolver essa perspectiva, foi realizado um levantamento preliminar de materiais produzidos por diferentes docentes (tais como planos de ensino, conteúdos programáticos, experiências pedagógicas desenvolvidas, entrevistas, etc.), ao lado de uma retomada do contexto político recente, no qual se verificam várias tendências de recrudescimento de valores democráticos associados aos DH e intensificação de posturas e discursos autoritários que combatem os princípios da EDH.
What Anne Taught Me About Living with Tragedy and Grief
Authors: Klein Lori
Published: August 2022

How did Anne’s wisdom assist my coping with my mother’s mental illness and traumatic death? This essay draws on William Worden’s four tasks of mourning and explores Anne’s willingness to outwardly express strong emotion in response to death and other losses. Today, Anne’s wisdom guides me in my work as a chaplain. (Note: the Author also includes a quote in the abstract).
Evaluating the roles spinal plasticity and an accessory inspiratory muscle have in a rodent model of respiratory motor neuron death
Authors:   , Borkowski Lauren Faith
Published: August 2022

Death by ventilatory failure most frequently occurs in patients with neuromuscular diseases in which there is a loss of respiratory motor neurons. There are currently no significant treatments to prolong or correct for these respiratory deficits. Genetic rodent models of motor neuron loss develop many phenotypes (e.g., dysphagia, limb paralysis, etc.), so in order to study how motor neuron death only impacts respiration and to develop therapeutic interventions, we have developed an inducible model of respiratory motor neuron death. Briefly, rats are intrapleurally injected with cholera toxin B conjugated to saporin (CTB-SAP), which selectively eliminates respiratory motor neurons. Surprisingly, this model displays considerable respiratory plasticity that functions over time to preserve eupneic ventilation. Thus, the fundamental goal of this dissertation is to determine potential strategies that preserve eupneic ventilation following respiratory motor neuron loss. Our data suggest that respiratory plasticity requires different G-protein-coupled receptors and downstream signaling and that the exhibited plasticity is differentially affected by COX1/2-induced inflammation over the course of CTB-SAP induced neuropathology, which may collectively represent one way eupnea is maintained. Additional pilot data indicate diaphragmatic amplitude is decreased in CTB-SAP treated rats, which suggests that extradiaphragmatic muscles (e.g., accessory inspiratory muscles such as the pectoralis minor muscles that can be utilized in disease/injury) are also utilized to maintain eupneic ventilation. Our data suggest that pectoralis minor activity is increased in CTB-SAP rats vs. controls and is further increased in 28d vs. 7d CTBSAP rats. The overall hypotheses of this dissertation are that following CTB-SAP treatment: 1) respiratory plasticity requires differential activation of G-protein-coupled receptor pathways; 2) respiratory plasticity is differentially impacted by COX1/2-induced inflammation; and 3) pectoralis minor muscle amplitude is increased to maintain eupnea. This project will advance our understanding of potential targets (i.e., receptors, inflammatory markers, or muscles) that could be harnessed or stimulated to further preserve and/or improve ventilatory function and quality of life in patients with neuromuscular diseases that are suffering from respiratory motor neuron loss.
Investigating age- and virulence factor- dependent innate immune activation during neonatal meningitis associated E. coli infection
Authors:   , Chambers Catherine Ann
Published: August 2022

Neonatal meningitis-associated Escherichia coli (NMEC) is a leading cause of early-onset sepsis and meningitis. While current antibiotic protocols have significantly reduced mortality associated with neonatal sepsis and meningitis, surviving infants are at a significantly increased risk of developing life-long neurologic impairment compared to healthy infants. This continued risk of lasting neurologic damage along with a recent rise in antibiotic resistant NMEC strains has precipitated a need for new therapeutic strategies. Targeted immune-based therapeutics may serve as desirable adjunct therapies; however, there are many challenges to their development. The neonatal immune system is immature compared to the immune system of adults, leading to an increased risk of infection. Here we assess the role of IL-1 secretion, which is known to be diminished in neonates, in the pathogenesis of a murine model of NMEC infection. We further highlight one potential mechanism for decreased IL-1 secretion during the neonatal period. To further complicate the development of immune-based therapeutics aimed at treating NMEC infection, NMEC strains can possess many different virulence factors with the potential to alter immune cell activation. While some of these factors, such as OmpA, have been well-characterized in the context of NMEC infection, many potential virulence factors have not. Here we show that the pore-forming toxin [alpha]-hemolysin activates purinergic receptors, leading to improved bacterial clearance and decreased mortality in a neonatal mouse model of NMEC infection. Together, the data presented here provides new insight into both neonatal immunity and the role of virulence factor-specific immune activation on the pathogenesis of NMEC infection, and may serve as a stepping stone for the development of not only new immune-based therapeutics, but also new diagnostic and prognostic tools for use during neonatal infection.
Dynamic spatial-temporal point process models via conditioning
Authors:   , Okenye Justin Obwoge
Published: August 2022

We propose and investigate dynamic spatial-temporal point process models for independent and interacting events. The models for independent events are dynamic spatial-temporal Poisson point process (DSTPPP) model that account for temporal and spatial clustering. The models proposed for events with interaction are Markov (Gibbs) space-time point process models. We model the intensity function of a DSTPPP via conditioning arguments that allow for additional interpretations and inclusion of well-known point process models as special cases. Depending on the nature of the questions to be answered, the in- tensity function of a DSTPPP can be modeled in several ways. First, we develop models via conditioning on the time component of the events and then consider conditioning on the location component of the events. Modeling, simulation and computation are accomplished in a fully hierarchical Bayesian framework. Finally, we focus on dynamic marked Markov space-time point processes, where the events are allowed to interact with each other across time and space. Once again the hierarchical Bayesian framework is invaluable in this case, since it allows us to introduce dynamic process models via conditioning. The methodolo- gies are illustrated using simulated data, and several applications, including modeling and inference for earthquake events in California, and tornado events in Missouri.
Function and evolution of the crocodyliform feeding apparatus
Authors:   , Sellers Kaleb
Published: August 2022

The evolution of crocodylians from their suchian ancestors represents one of the great transformations in vertebrate evolution. Modern crocodylians have flat skulls and generate high forces during feeding, but crocodylian ancestors have tall skulls and lack most of the characters that help crocodylians generate and resist high forces. Thus, the evolution of crocodylians involved a substantial reorganization of the feeding apparatus. Although changes to skull shape in the lineage leading to crocodylians have received a great deal of attention, the functional consequences of shape change on feeding biomechanics are unclear. This dissertation addresses this gap in our knowledge by building high-fidelity biomechanical models to ask questions about the evolution of skull shape and feeding performance in the lineage leading from early suchians to extant crocodylians. I use detailed 3D muscle attachment sites to estimate muscle forces and distribute forces on 3D finite element models using an approach validated against in vivo data. These finite element models are used to estimate bite and joint forces. I use traditional linear morphometrics to characterize skull flattening. I also develop novel methods to quantify and visualize joint articular surface shape. These results are analyzed using phylogenetic comparative methods and ancestral character state reconstruction. My results show that skull flatness is linked with inefficient muscle geometries and that these geometries developed stepwise in the lineage leading to crocodylians. I found that joint shape best reflects the highest-magnitude loads that the skull experiences, that the orientation of joint loading tracks with skull flatness, and that peak joint pressure falls within the range predicted by chondral modeling. This study shows that extant crocodylians rely on extra muscle mass to produce high bite force with inefficient muscle configurations and that the derived, suturally-immobilized cranial joints are key features of the feeding apparatus that mitigate mechanical inefficiencies imposed by a flat skull. Overall, these results depict a coordinated evolution of skull shape, muscle anatomy, joint surface shape, and biomechanical performance in the lineage leading to Crocodylia and have broad implications and applicability to all vertebrate musculoskeletal systems. This dissertation research represents an important step in improving our understanding of the biomechanics of musculoskeletal transitions.
Rekonfigurasi Jaringan Distribusi Radial Di Penyulang Purwoasri Berbasis Modified Imperialist Competitive Algorithms (MICA)
Authors: Ali Machrus , Rukslin Rukslin , Nurohmah Hidayatul , Arie Pambayun Yoga , Zaini Achmad
Published: July 2022

Radial distribution network configuration is difficult to simplify because it is very complex. This network reconfiguration is used to redesign the configuration form of the radial distribution network by opening and closing switches on the distribution network. Purwoasri feeders, Rayon Kertosono, Mojokerto area have very large losses that need to be reconfigured. The resulting power flow will produce a network power loss as a result of the configuration. The reconfiguration process will be repeated until the configuration form that produces the smallest power loss is obtained. The number of feeders and buses on the network will be difficult if done with manual calculations and requires a very long time, so solving the problem must use a computer program. Network reconfiguration using the Matlab 2013a program will analyze its power flow using the Newton Raphson method and using the artificial intelligence method, Modified Imperialist Competitive Algorithms (MICA). With this method, it was obtained before the reconfiguration of the network suffered a loss of 89,724 kWatt after the reconfiguration had a loss of 54.8299 kWatt. The results of reconfiguration can reduce losses of 0.6173 kWatt or 38.95688%.
Sosialization of Chitosan as Natural Preservation for Palm Tree’s (Arenga pinnata Merr.) Sap in Akelamo, Central Oba
Authors: Albaar Nurjana , Rasulu Hamidin , Husen Janiah , Wulansari Angela
Published: August 2022

Palm tree’s (Arenga pinnata Merr.) sap is the main ingredient for palm sugar. Palm tree’s sap is obtained by tapping the male flowers of palm tree. The sap is rich in sugar thus it is easy to be fermented. Palm farmers in Akelamo Village use soap as a preservation agent to prevent fermentation during the taping and loading period before the sap is cooked. Soap is a non-food product which is unsafe to be used in food product. Based on this fact, the community service program was designed to educate and share information about the danger of non-food preservation agent in food product, and also introduce chitosan as potential natural preservation to prevent fermentation process on palm tree’s sap among the palm farmers in Akelamo Village. There were four activities that had been done, such as discourse about food preservation and chitosan as natural preservation agent, workshop about how to apply chitosan to prevent fermentation during palm tree tapping, workshop about how to make palm sugar, and interactive dialogue with palm farmers. All the activities were done succesfully. The farmers were actively participated in every activity during the program.
The Influence of Shoot Location and Mechanical Treatment Following Grafting on Siamese Orange Seedling Development
Authors: Zairani Fitri Yetty , Hasani Burlian
Published: August 2022

This study aims to determine the influence of the location of the buds and mechanical treatment after grafting on the growth of orange seedlings. The study used a Randomized Group Design (RAK), arranged factorially with nine combinations of treatments and three tests. The first treatment factor used is the budding eye system (P), consisting of 3 levels, namely P1: Fourth Budding Eye; P2: Fifth Budding Eye; and P3: Sixth Budding Eye.   The second factor is mechanical treatment after grafting (K) consisting of 3 levels, namely K1: Rootstock Cutting; K2: Rootstock Restraint; and K3: Rootstock Bending. The parameters observed are the percentage of grafting of living plants, the time of bud exit, the number of leaf blades, the twisting of the stem of the grafting bud, and the length of the grafting bud. Based on the observations on the percentage of grafting that live after mechanical treatment of all budding eye location treatments, it shows that the fifth bud (P2) location treatment gives a higher rate of live grafting, which is 100% compared to other treatments. The treatment of the location of the fifth bud gives the best results against the time of bud exit, the number of leaves, the twisting of the grafting stem and the length of the grafting bud. Mechanical treatment of rootstock restraint after grafting gives the best results against the time of bud exit, the number of leaves, the twisting of the grafting stem and the length of the grafting bud. The interaction between the treatment of the fifth bud location treatment and the mechanical treatment of rootstock holding gave the best results against the growth of Siamese orange seedlings.
Potential Rice Straw as Biofertilizer in Rice (Oryza sativa L.) in Tidal Soils
Authors: Marlina Neni , Aryani Ida , Khodijah Khodijah , Marlina Marlina , Rompas Joni Phillep , Yulianto Deny , Nunilahwati Haperidah , Husna Nurul , Aluyah Cik
Published: August 2022

Rice productivity in tidal lands can be achieved by using local resources, including managing rice straw as a biological organic fertilizer (POH). The biological organic could be used with ingredients rice straw: chicken manure: Azospirillum bacteria, and Phosphate Solvent Bacteria (6:4:1). These can increase soil fertility, nitrogen, and phosphorus and potassium nutrients through the activity of microorganisms (Azospirillum and Phosphate Solvent Bacteria). This study aims to obtain the right dose of POH to increase rice production in tidal soils. This research was carried out in an experimental garden, using tidal soil media type C overflow from Banyuurip Village, Banyuasin Regency. Testing using field experiments. The layout used a Randomized Group Design with 4 treatments repeated 6 times, namely POH (D) doses: 0 kg/ha (D0), 200 kg/ha (D1), 400 kg/ha (D2), 600 kg/ha (D3). The best results were found in using POH with a dose of 600 kg/ha, which was 41.67 g / plant and increased production by 87.96% compared to without POH.
MENINGKATKAN KUALITAS GENERASI MUDA MELALUI PEMERIKSAAN HAEMOGLOBIN, HEMATOKRIT DAN GULA DARAH SISWA SMA NEGERI I TANJUNG SAKTI
Authors: Haiti Margareta , Ire Tominik Victoria , Febriani Diana
Published: July 2022

Hemoglobin is the main protein of the human body that serves as a carrier of oxygen to the tissues and transport media of carbon dioxide from the body tissues of the lungs, the oxygen the body needs as a source  of  energy  that  will  generate  power  so  that  humans  are  able  to  execute  duties  or  daily occultation. The main source of haemoglobin is iron which is the source of the nutrient intake we consume.  Hemoglobin  examination  is  one  of  the  most  frequent  blood  tests  performed  by  each laboratory because hemoglobin examination in the blood has an important role in the diagnosis of a disease. The usefulness of examining hemoglobin levels is to assess the level of anemia, response to anemia therapy, or disease progression associated with anemia and polycythemia. Hematocyte examination is also important for assessing the normal state or not of erythrocytes and blood volume as well as related to hemoglobin in the body. Decreased hematocrit is one indicator of anemia caused by various factors. Blood glucose is the result of carbihydrate decomposition and glycogen changes in the  liver.  Glucose  examination  in  darh is  a  screening  procedure  that  shows  the  inability  of the pancreas to produce insulin, the inability of the small intestine to absorb glucose, the inability of cells to use glucose efficiently or the inability of the liver to collect and solve glycogen.

Keywords: Haemoglobin, Hematocrit and Glucose levels in blood
PENGARUH KUALITAS PRODUK DAN KUALITAS PELAYANAN TERHADAP KEPUASAN PELANGGAN MOBILE BROADBAND DI KOTA PALEMBANG
Authors: Hendrianto Hendrianto , Natalisa Diah , Eka Dian
Published: August 2022

This study aimed to analyze product quality and service quality on customer satisfaction.Respondents were the customer of mobile broadband product in Palembang city. Both primary and secondary data were gathered. Secondary data were gathered from various sources such as journals, books and other related publications. Primary data were gathered using questionnaire which were distributed to the respondents. This research used a random sampling technique, a total sample of 100 respondents were obtained. Various statistical analysis tests such as validity, reliability and classical assumption tests were employed. Using a multiple linier regression analysis, the result indicated thatproduct quality and service quality had positive and significant effect on customer satisfaction. The mobile broadband company is suggested to evaluate about the price, product quality, and service quality to provide costumer satisfaction.
RESEARCH OF BIOENERGY POTENTIAL ON IMPROVING ENERGY EFFICIENCY AND ENVIRONMENTALITY IN TRANSPORT PROJECTS
Authors: Holub H. , Kharuta V. , Zaiats O. , Tkachuk M.
Published: August 2022

The article considers the problems of energy efficiency management of the rolling stock of the transport sector. The operation and operation of vehicles are analyzed and it is determined that road transport is the main consumer of energy resources in the transport sector, which is about 90%. Road transport requires 6.5 times more fuel than rail, and 5 times more fuel than sea or river. It has been studied that the transport sector has a negative impact on environmental friendliness due to high emissions. To successfully solve this problem, it is necessary to use bioenergy, which will increase the energy efficiency and environmental friendliness of the transport sector and is a strategy for the development of the transport sector of the country and the European Union. An analytical review of legislative acts, namely EU directives and national transport strategy for the period up to 2030, which regulate the promotion of energy efficiency in transport. The main groups of tools and the use of information technology are considered, which allow to achieve the set goals in the development of energy efficiency in transport. The impact of alternative fuels resulting from the processing of biological waste or biological raw materials for the country's transport sector, in particular road transport, which will significantly reduce CO2 emissions, has been studied. Biofuels are able to provide clean energy for all modes of transport and are currently the most important type of alternative fuel. Its influence on improving the energy efficiency and environmental friendliness of the transport sector has been studied.