bluuebunny/crossref_metadata_2025 huggingface dataset:
Interacción de dos hongos toxicogénicos con una cepa de Streptomyces sobre el desarrollo de plantas de trigo
Authors: Fulgueira Cecilia , Borghi Alfredo , Gattuso Marta , Gattuso Susana , De Bracalenti Blanca
Published: April 2019

Entre los microorganismos antagonistas de los suelos donde se cultivan cereales se hallan Streptomyces capaces de producir sustancias inhibidoras que pueden afectar la viabilidad y capacidad de diseminación de distintas especies de Aspergillus Y Fusarium y su capacidad para producir aflatoxinas y trichotecenos.El objetivo del presente estudio fue evaluar el efecto de la interacción entre hongos toxicogénicos (Aspergillus parasiticus y Fusarium tricinctum NRRL 3299) Y Streptomyces sp.antagónicos del crecimiento de tales hongos sobre el desarrollo de plantas de trigo.Se realizaron las siguientes actividades: a) inoculación de semillas de trigo, con el Streptomyces inhibidor, b) estudio del poder germinativo de las semillas de trigo, c)cultivo en cámara invernáculo de semillas inoculadas y sin inocular sembradas en tierras con y sin los hongos toxicogénicos, d) comprobación de la invasividad o ataque de los hongos mediante el rociado de espigas de plantas provenientes de suelos infectados con una suspensión de conidios de los hongos infectantes,e) determinación de las variaciones en las características botánicasde las plantas de trigo.Se pudo concluir que: 1) la presencia de hongos toxicogénicos no alteró el poder gemtinativo de las semillas de trigo, 2) el desarrollo vegetal, número y peso promedio de los granos de las plantas provenientes desuelos infectados con los hongos toxicogénicos fué significativamentemayor al de las plntas crecidas en tierra esteril,  3) el estudio anatómico de las plantas no puso en evidencia invasión o ataque por parte de los hongos.
A HISTÓRIA DE UMA INCUBADORA DE EMPRESAS: RESGATE DE SUA PRIMEIRA DÉCADA
Authors: Dal Molin Wissmann Alexandre
Published: April 2019

Esforços vêm sendo empreendidos na busca por mecanismos que fortaleçam as organizações e contribuam para o desenvolvimento social e econômico. O resgate da memória de instituições caracteriza-se como uma destas práticas, permitindo a compreensão do seu passado, o diagnóstico do presente e a projeção de ações. Diante deste cenário, o trabalho objetiva resgatar a história da Incubadora de Empresas de Inovação Tecnológica – Criatec, evidenciado seus marcos históricos dentro de sua primeira década. Adotou-se como estratégia de pesquisa o estudo de caso. Os procedimentos técnicos utilizados foram a pesquisa bibliográfica, documental e de campo. Neste último caso, a entrevista semiestruturada foi empregada e o diálogo ocorreu com um dos atores envolvidos no caso. Os resultados revelam o caminho de dificuldades e empreendedorismo que a criação de um espaço de desenvolvimento na região acarreta. São identificados os vínculos criados pela Incubadora, que permitem, nos anos iniciais, a construção dos alicerces do trabalho e, posteriormente, a consolidação e expansão das atividades. Também são expostas as metamorfoses da Incubadora em busca de reconhecimento externo e interno à Universidade. O trabalho garante a armazenagem da história através de significados, memórias e de informações sobre este mecanismo de desenvolvimento. Além disto, o resgate do passado, possibilita o entendimento do presente e a visualização de ações futuras.
COSMOCENE PEDAGOGY: SUSTAINABLE LEARNING IN TIMES OF THE ANTHROPOCENE
Authors: Pereira Vilmar Alves
Published: April 2019

This article aims to present some developments and advances in Cosmocene Ecology. Hermeneutical horizon’s study in the field of Fundamentals of Environmental Education, it starts from a succinct recovery of the environmental crisis and the demarcation of the Anthropocene Age, later it retakes the main theses of the mentioned ecology and finally demonstrates how this Ecology can be translated in educative principles whose movements and learning can result in the Cosmocene Pedagogy. It is a study that proposes to offer, besides reflections, sustainable principles so that we can educate ourselves to seek a greater guarantee of a decent life based on another concept of development: human development. Philosophical hermeneutics is used as a methodological approach whose interpretative and understanding effort points to the urgent need to reassess the position we have traditionally assumed in the universe. It also points to the need to recognize the knowledge of traditional peoples who have always inhabited the world sustainable development.
PERFIL SOCIOECONÔMICO DOS POBRES: UMA ANÁLISE COM BASE NA REGIÃO NORDESTE E EM SUAS MESORREGIÕES NO PERÍODO DE 1980 A 2010
Authors: Moreira Aristides dos Santos Anderson , Castro Moreira da Silva Vinícius
Published: April 2019

O objetivo deste artigo é analisar o perfil socioeconômico dos pobres do Nordeste e de suas mesorregiões, utilizando os microdados do Censo no período de 1980 a 2010. Primeiramente, os pobres foram classificados pela abordagem monetária com base na linha de pobreza do Programa Bolsa Família (R$140,00). Posteriormente, aspectos além da renda foram analisados, tendo como foco indicadores de privação dos pobres nas dimensões: educação, infraestrutura do domicílio e posse de bens. Houve melhorias importantes ao longo do período e uma menor distância entre os indicadores de pobres e não pobres. O saneamento, educação dos adultos e mesmo a posse de bens básicos como geladeira se encontram em um patamar de privação bastante insatisfatório. Há maiores privações para os pobres da área rural e existência de heterogeneidade entre as mesorregiões. Políticas públicas precisam levar em consideração que os pobres classificados monetariamente possuem diferentes condições socioeconômicas de acesso a bens e serviços básicos, com precariedade, principalmente, no meio rural e em mesorregiões específicas.
Småstatsrealisme i 70 år
Authors: Tamnes Rolf
Published: April 2019

Norges tilslutning til Atlanterhavspakten i 1949 markerte et vendepunkt i norsk sikkerhetspolitikk. Norsk sikkerhet kom til å hvile på NATO, med USA som fremste støttemakt. I den senere tid er det transatlantiske samarbeidet kommet under press, og det stilles spørsmål ved den amerikanske garantien. Det kan medføre en alvorlig utfordring for norsk sikkerhet. På lang sikt vil det kunne vokse frem et strategisk partnerskap i Nord-Europa og Norden, som kan bli en bærebjelke for norsk sikkerhetspolitikk og markere et nytt vendepunkt. Norges strategiske omgivelser er omskiftelige. Samtidig finnes noen bestandige trekk i norsk sikkerhetspolitisk tenkning, som kan betegnes som småstatsrealisme. Viktigst er betydningen av å bli beskyttet av større makter, men også å holde dem på avstand, samt folkeretten og den globale orden som sikkerhetsnett, der rett går foran makt.
Perfil epidemiológico de las atenciones en emergencia del Hospital Básico de Machachi en el año 2018. Estudio descriptivo para determinar la pertinencia de la atención brindada
Authors: Viteri Mora Andrés
Published: April 2019

Introducción: El servicio de emergencia del Hospital Básico de Machachi presenta una gran demanda lo cual causa el congestionamiento del servicio y de el resto de servicios del hospital en general superando la oferta tanto de camas hospitalarias como profesionales, el presente estudio se lo realiza para poder establecer cuales son las principales causas de consulta al servicio de emergencia y determinar el porcentaje de las mismas que ameritaban un tipo de atención especifica por el servicio y obtener un perfil epidemiológico de las patologías que se atienden en la emergencia determinar el patrón de utilización del servicio por la población local y la relación con variables demográficas con toda esa información brindar un instrumento de análisis para tomar medidas orientadas a optimizar el uso del servicio por parte de la población con un adecuado y eficaz manejo de los recursos del hospital

Objetivos: Establecer el porcentaje de atenciones en el servicio de emergencias del Hospital Básico Machachi entre enero y diciembre de 2018 que eran pertinentes de acuerdo a la clasificación de triaje usada en la institución.

Métodos: Estudio epidemiológico descriptivo transversal. Base de datos con información obtenida de la revisión de los formularios 008 de atención de emergencia de todo el año 2018 en el servicio de emergencia del Hospital Básico Machachi para clasificar la atención como emergente o no emergente de acuerdo al sistema de triaje de Manchester.

Resultados esperados: Demostrar la sub utilización del servicio de emergencia del Hospital Básico Machachi para determinar los correctivos a implementar
Caridad como reforzamiento de somatización: un estudio cualitativo
Authors: Peñafiel-Mendoza Susana
Published: April 2019

La somatización es un motivo frecuente de atención en primer nivel, es común en la población general, entre el 17 y 50 %, por lo que necesitamos no solo de lo que se relaciona con el diagnóstico médico de esta afección, sino de la profundización del conocimiento. (1)Si bien existen varios factores que pueden desencadenar su aparición no sabemos qué factores pueden fomentar su reforzamiento.
Asociación Asociación entre Polifarmacia y Prescripción inapropiada según la clase social en adultos mayores de Bucaramanga
Authors: Bueno Silvia Juliana
Published: April 2019

Resumen: La polifarmacia y la PI se han visto relacionadas con múltiples variables, incluidas variables socioeconómicas, sin embargo, la evidencia en cuanto a lo anterior es escasa y heterogénea. Objetivo: Evaluar la prevalencia de polifarmacia y prescripción inapropiada de medicamentos en adultos mayores de 60 años  según su clase social. Material y métodos: Estudio piloto de diseño descriptivo corte transversal en la ciudad de Bucaramanga, con una muestra de 135 adultos mayores de 60 años. Se realizó una encuesta donde se registraron datos sociodemográficos, estado de salud en el último mes, comorbilidades, medicamentos de uso crónico y funcionalidad en base a escalas. Resultados:

No se encontró asociación estadísticamente significativa entre prescripción inapropiada, polifarmacia, e infra prescripción con la clase social y con el nivel educativo (P=0,639). Sin embargo, el tener una afiliación al sistema de seguridad social de tipo subsidiado estuvo significativamente asociada a la infra prescripción (P<0,029), la presencia de ingresos mensuales se vio asociado con la presencia de polifarmacia (P<0,029) y prescripción inadecuada (P<0,033). Conclusiones: Existe una asociación entre algunas variables socioeconómicas con polifarmacia y PI, además el número de médicos tratantes y algunas especialidades médicas como cardiología y ortopedia son más propensas a presentar mayor porcentaje de polifarmacia.
INFECCION URINARIA POR Kluyvera ascorbata: REPORTE DE UN CASO
Authors: Sanchez-Buitrón Susan Katherine , Sigüenza-Asmad John Dexter , Vargas-Narro Roberto Carlos , Vargas-Pesantes Antony Francescoli , Aguilar-Urbina Edi William
Published: April 2019

La bacteria Kluyvera ascorbata forma parte de la microbiota normal del tubo digestivo humano; pero en ocasiones, puede ocasionar infecciones potencialmente graves. Se presenta el caso de una paciente con pancreatitis aguda que luego de un antecedente de hospitalización y de portar sonda vesical, reingresa al hospital por una reagudización de su enfermedad acompañada de molestias urinarias, aislándose en urocultivo a Kluyvera ascorbata multirresistente. Este cuadro clínico pudo deberse a una infección intrahospitalaria relacionada al uso de sonda vesical; además, existe la posibilidad de que la paciente desarrollara una bacteriemia asociada a Kluyvera ascorbata.

PALABRAS CLAVE: Kluyvera, Infecciones Urinarias, Pancreatitis (DeCS)
LINFOMA NO HODGKIN DIFUSO DE CELULAS GRANDES INMUFENOTIPO B CON AFECTACIÓN PULMONAR: REPORTE DE CASO
Authors: Martínez Isaac Steven , Coronel Carina , Macías Eddyn Ruben , Melo Marco Vinicio
Published: April 2019

Introducción: Los linfomas No-Hodgkin son un grupo de tumores malignos, cuyo origen se manifiesta más frecuentemente en las células B en adultos, se caracterizan por su capacidad para realizar metástasis extraganglionares, por su agresividad, y su asociación a un mal pronóstico. Presentación del caso: Paciente femenina de 63 años acude a facultativo por totos productiva, disnea, hiporexia y pérdida de peso. Al examen físico se evidencia murmullo vesicular disminuido y roncus. Tomografía torácica muestra masa espiculada. Se realiza broncoscopía flexible encontrándose infiltración GIII y estenosis. La biopsia de dicha lesión muestra distribución angiocéntrica, angiodestructiva y necrosis. Inmunohistoquímica concluye Linfoma no Hodgkin difuso de células grandes inmunofenotipo B. Conclusión: Los linfomas No Hodgkin sin reordenamientos genéticos poseen relativamente buen pronóstico. Se recomienda en pacientes estadío avanzado quimioterapia basada en antraciclina más rituximab.
Using Dry Olive Leaves for Oil Pipes Corrosion Inhibitor
Authors: Hani Ghada Mazin , Mahdi Sahib M. , Majeed Amer H.
Published: April 2019

At the present time the use of corrosion inhibitors is a good solution to maintain or reduce the corrosion problems in the equipment, so nowadays the production of inhibitors all non-toxic, natural and cheap is the most important demand. In this study dry olive leaves extraction used as inhibitor in a temperatures similar to the average temperature in Iraq, so as to bring the picture of reality as much as possible, at (25 °C and 45 °C) and solution was prepared in the following concentration to stimulate the field environment for oil extracting 19.2 % of sodium chloride (NaCl), 8% of calcium chloride (CaCl), 1.08 % of magnesium chloride (MgCl) and saturated with Co2 gas, the corrosion rate of steel sample was measured be using a potentiostat device with reference of calomel electrode. The result was, the dry olive leaves extract is an effective inhibitor material. Dry olive leaves extraction inhibitor has a low corrosion rate at 25OC and 45OC and the Corrosion rate decrease with increasing temperature for oil extraction solution, From the EDS test found that high percentage of carbon and oxygen caused to produce many compounds like the phenolic compound of the olive leaves is the responsible of inhabitation effect of the olive leaves.
Reflections on Pottery Art in the Oil Rich Niger Delta Region of Nigeria: A Study of Pottery Art in Akwa Ibom and Rivers States
Authors: Peters Edem Etim
Published: April 2019

Niger Delta region is very rich in oil and gas deposits, clay, agricultural land, fisheries, extensive forest and other resources. They are nine states which make the region namely, Abia, Akwa Ibom, Bayelsa, Cross River, Delta, Edo, Imo, Ondo and Rivers. The most oil producing communities among them are Akwa Ibom, Bayelsa, Edo, Delta and Rivers State. Clay is equally found in abundance in all the states like crude oil is found in Niger Delta communities. The available clay mineral in the region has the capacity to transform the nation’s economy if properly utilized. Clay is the basic material for pottery or ceramics production. It is also used to ease the penetration of pipes in drilling of crude oil. This paper looks at the practice of pottery in Niger Delta Area with a focus on pottery practice in both Akwa Ibom and Rivers States. Indigenous and contemporary pottery or ceramics practices in these communities indeed have played vital role in the economic, social religious and cultural ways of life of the people. Clay products such as dinnerware and sanitary wares and others are highly sought for and they have the capacity to boast the national economy as experienced in other nations such as Japan, Italy, Britain, United States of America, India and China among others. Data were collected from both primary and secondary sources and were subsequently assessed. The result shows that proper utilization of clay found in Niger Delta has the potential to create numerous job opportunities for the teaming population of youths in the region. The availability of abundant clay in the region, if well harnessed could adequately compete with crude oil exploitation for economic purposes in the region.
Using Diagnosis and Life Cycle Cost to Improve Reliability of an Excavator
Authors: Enyindah Ndamzia Clement , Amadi Rex Kemkom
Published: April 2019

Diagnosing of equipment before actual failure and reduced total ownership cost of excavator (TOC) is a significant issue for the mining and civil construction industries to unavoidably consider. Consequences of prolonged project execution time and extra cost due to sudden breakdowns are better minimized by studying the reliability of the equipment and having knowledge of life cycle cost model which was used in this research to ascertain the economic replacement time and cost of an excavator. Results from life cycle cost analysis carried out on an excavator show that the replacement time and total ownership cost of excavator 320C from 2010 to 2017 is 8 years and N10, 214 respectively.
Formulation of White Board Marker Ink Using Locally Sourced Raw Materials
Authors: Dagde Kenneth K , Nwosa Godbless , Ukpaka Chukwuemeka
Published: April 2019

This research work was conducted to demonstrate the mechanism of white board marker ink production using locally sourced raw materials such as charcoal and used lube oil. In the production of the ink, the charcoal served as a pigment, used lube oil served as the primary binder or resin, ethanol served as solvent and gum Arabic served as an additive. The charcoal was obtained from processing of Mango, Oil bean (Ugba) and rubber trees, which were further crushed to their finest particles respectively and the used lube oil was obtained from mechanical engineering servicing unit of automobile engines. The crushed charcoal samples were characterized to determine the physio-chemical properties of some mineral elements such as Ca, Cu, P, K, C, S, N. however the mineral component that controlled the production of this ink was the Carbon content. The different ink samples were formulated in terms of odour, colour, hazardous reaction, pH, density and viscosity and compared with that of international standards. Results obtained showed a good match, indicating the reliability and the quality of the produced white board marker ink. The pH results for Ugba ink = 5.43, Rubber ink = 6.79, and Mango = 7.41. Empirical models were used to predict concentration with that of experimental values, a plot of concentration against time in terms of production yield revealed that the order of magnitude was rubber>Ugba>Mango whereas in terms of penetration and writing ability Ugba>rubber>mango. Furthermore, the research demonstrates the significance of the characteristics of the charcoal and the used lube oil in the quality of the end product. Finally, the research revealed that ink produced from the oil bean (ugba) charcoal and lube oil was best in terms of write-ability and quality in the production of white board marker ink.
Application of a Particle Swarm Optimization for Improving Voltage Profile with Distributed Generation: A Case Study of 33/0.415KV Abuja Airport Injection Substation
Authors: Oodo Stephen , Owolabi Felix Sanjo
Published: April 2019

The important of electric power distribution is to have centralized plants distributing electricity through Distributed generation (DG) which reduces the cost of maintenance on transmission and distribution station and also improve voltage profile. This research paper present the application of generation based on Biogas power renewable energy source to the Distribution network and how it stabilizes the network by normalizing the fluctuating voltage profile at the distribution end of power system. A Particle Swarm Optimization (PSO) model was performed and evaluation of the impact of the DG by stimulating the developed model in the system. A mathematical formulation and optimization algorithm was performed using the MATLAB/Simulink program. The results obtained were correction of the faulty buses voltages and stable power supply which is 29.4% better than the conventional one. The result shows the implementation of the optimisation technique has improved the energy efficiency of the distribution network.
Experimental Characterization of Geometric Aspects of the Behavior of Magnetic Shape Memory Materials and Theoretical Interpretation
Authors: Hernandez Juan Manuel , Mullner P. , Linquist P. , Carreraa J.
Published: April 2019

Small samples of a Ni-Mn-Ga single crystal of three different geometries were subjected to bending by applying a rotating magnetic field. The magneto-mechanical behavior of the sample in cantilever was analyzed and special attention was given to elongations and curvature along the deformation process. A sequence of 3000 images was made using a high-resolution camera and the data was analyzed using a code in Matlab. Furthermore, the geometric analysis showed that, when the magnetic field is equal to cero, the sample do not recover its original shape totally and the presence of a pseudo-elastic behavior was observed. Analysis and interpretation of the data allows the presentation of some hypotheses concerning to the crystalline structure and the role of dislocations, represented by a dislocation density, in the martensite phase of these materials. These hypotheses are discussed more formally in the second part of this paper. Some experiments are proposed that would give the opportunity to a wider theoretical knowledge of MSMM.
Long Term Evolution (LTE) Network Evaluation in the South-West Region of Nigeria
Authors: Kuboye Bamidele Moses
Published: April 2019

The LTE broadband evolved from an earlier Third Generation Partnership Project system which is known as the Universal Mobile Telecommunication System (UMTS), which evolved from the Global System for Mobile Communications (GSM). The network architecture of this system has been designed with the aim to support a packet-switched traffic with seamless mobility and great quality of service. The main goal of the LTE is to provide a high data rate with low latency and a packet optimized radio access technology that supports deployment of bandwidth. Hence, this study is based on the evaluation of the LTE network in the south-west region of Nigeria. This study evaluates the LTE network strength in the South-West region of Nigeria. Questionnaires were administered among users in these areas randomly. Thereafter, data were analyzed and research questions were answered from the analyzed results. The results showed that 9Mobile and MTN has the best quality of service of LTE network in South-West, Nigeria, also that the LTE network has not really been active in Osun and Ekiti states.
Electrical Energy Large-Scale Storage, A Possible Application in the Russian Federation
Authors: Savard Christophe , Nikulina Anni , Mecemmene Céline
Published: April 2019

There are many solutions for storing energy, they can be either mechanical, thermal, chemical, electrochemical or electrical. In a context of smart-grid and micro-grid development, it is necessary to be able to store electrical energy at various points in the network: at the source for intermittent resources, in the network itself to have reserves to ensure exploitation and in consumption areas. Each solution is more or less relevant depending on the storage needs in terms of both power and energy. The evolution of electricity demand in the Russian Federation is a good example to illustrate this issue, especially since it is now planned that all new construction will have an energy storage system, so as to contribute to a better overall exploitation of the network. For intermediate storage, on the network, there is definite potential thanks to the old mines, in particular, that can be developed to store energy in the form of compressed air. In high consumption sites, it is also possible to use storage in the form of large energy banks made up of batteries.
Bradycardia Detection using ECG Signal Processing and MATLAB
Authors: Kabari Ledisi Giok , Onwuka Ugochukwu C.
Published: April 2019

Electrocardiogram is the record of electrical activity of heart. ECG is a test to detect and study normal rhythmic activity of the heart. Signal processing are very often used methods in a biomedical engineering research. This paper presents Bradycardia detection by utilization of digital signal filtering on electrocardiogram (ECG) using MATLAB. MATLAB was used to analyze and process ECG dataset gotten from Physionet online database with focus on R-R peaks to calculate the heartbeat, by applying high pass filtering and squaring the signal. The results obtained using MATLAB for ECG analysis and detection of arrhythmia is very fast and useful.
Los medios estatales de Argentina a partir de la asunción de la alianza Cambiemos en el gobierno nacional (2016-2018)
Authors: Linares Alejandro , Mallimaci María Andrea
Published: April 2019

Este trabajo releva el desempeño institucional de los medios del Estado nacional de la Argentina de 2016 a 2018, a partir de la asunción de la alianza Cambiemos en el gobierno nacional. Se analiza las principales decisiones que delinearon una política para su funcionamiento.

Para esto, se reseñan las modificaciones normativas, las iniciativas concretas y se recuperan las definiciones de los responsables institucionales. El diagnóstico sobre las tendencias y perspectivas en esta política se nutre de documentos públicos, entrevistas periodísticas y personales a sus directores, la normativa específica y textos académicos vinculados a la cuestión.

El trabajo concluye que a partir de la llegada de un nuevo gobierno nacional argentino en el cierre de 2015 se evidencia un cambio de perspectiva en la gestión de los medios estatales nacionales. En esta tendencia, las emisoras estatales se desplazan de un rol complementario y protagonista a otro subsidiario y marginal dentro del sistema mediático.
Cuerpo viviente y cuerpo vivido. Algunas reflexiones desde la antropología filosófica
Authors: Lombo, Giménez Amaya José Ángel, José Manuel
Published: April 2019

Frente el dualismo y al monismo, una visión realista del hombre es necesariamente unitaria, pero no simple o indiferenciada. Ello implica una consideración del cuerpo como integrante de la subjetividad, pero al mismo tiempo la trascendencia del yo respecto a la corporalidad. El cuerpo viviente constituye una unidad internamente articulada en su estructura y dinamismo, y se encuentra abierto a otras realidades corpóreas con las que forma una cierta unidad viviente.
Insertable cardiac monitor detection of silent atrial fibrillation in candidates for percutaneous patent foramen ovale closure
Authors: Scacciatella Paolo , Jorfida Marcella , Biava Lorenza M. , Meynet Ilaria , Zema Domenica , D’Ascenzo Fabrizio , Pristipino Christian , Cerrato Paolo , Giustetto Carla , Gaita Fiorenzo
Published: April 2019

Aim

An underlying atrial vulnerability or a preexisting misdiagnosed atrial fibrillation in some patients who are candidates for patent foramen ovale (PFO) closure may lead to an unnecessary percutaneous intervention. The aim of this work was to define paroxysmal atrial fibrillation rate, through a 6-month insertable loop-recorder monitoring, in patients over 55 years old with cryptogenic stroke and PFO.

Methods

PFO closure criteria: significant right-to-left shunt and at least one high-risk feature (permanent right-to-left shunt, atrial septal aneurysm, prominent Eustachian valve, recurrent brain ischemia, previous deep vein thrombosis, thrombophilia). Insertable cardiac monitoring criteria: previous cryptogenic stroke, more than 55 years and at least one atrial fibrillation risk factor (heart failure, hypertension, age older than 65 years, diabetes, atrial runs, left atrium dilatation, left ventricle hypertrophy, pulmonary disease, thyroid disease, obesity). Atrial fibrillation detection threshold: arrhythmia duration longer than 5 min.

Results

From January 2008 to March 2017, 195 patients underwent to loop-recorder monitoring. A total of 70 (36%) patients were candidates for PFO closure. The 6-month silent atrial fibrillation rate was 11.4%. In the arrhythmia-free cohort, 28 patients (45.2%) underwent percutaneous foramen ovale closure (group A) and 34 (54.8%) were medically treated (group B). Atrial fibrillation detection rate was 14.3% in group A and 0% in group B. The 36-month atrial fibrillation-free survival was 76%.

Conclusion

An occult preexisting atrial fibrillation may lead to unnecessary percutaneous foramen ovale closure in a significant proportion of patients. A 6-month loop-recorder monitoring may improve the patient oriented decision-making.
Arrhythmic risk stratification in patients with dilated cardiomyopathy and intermediate left ventricular dysfunction
Authors: Merlo Marco , Gentile Piero , Artico Jessica , Cannatà Antonio , Paldino Alessia , De Angelis Giulia , Barbati Giulia , Alonge Marco , Gigli Marta , Pinamonti Bruno , Ramani Federica , Zecchin Massimo , Pirozzi Fabrizio , Stolfo Davide , Sinagra Gianfranco
Published: April 2019

Aims

Arrhythmic risk stratification is a challenging issue in patients with dilated cardiomyopathy (DCM), particularly when left ventricular ejection fraction (LVEF) is more than 35%. We studied the prevalence and predictors of sudden cardiac death or malignant ventricular arrhythmias (SCD/MVAs) in DCM patients categorized at low arrhythmic risk because of intermediate left ventricular dysfunction under optimal medical treatment (OMT).

Methods

DCM patients considered at low arrhythmic risk (LVEF >35% and New York Heart Association class I-III after 6 ± 3 months of OMT) were analysed. An arrhythmogenic profile was defined as the presence of at least one among a history of syncope, nonsustained ventricular tachycardia, at least 1000 premature ventricular contractions/24 h, at least 50 ventricular couplets/24 h at Holter ECG monitoring. SCD/MVAs was considered as the study end-point.

Results

During a median follow-up of 152 months (interquartile range 100–234), 30 out of 360 (8.3%) patients at low arrhythmic risk (LVEF 47 ± 7%) experienced the study end-point [14 (3.9%) SCD and 16 (4.4%) MVA]. Compared with survivors, patients who experienced SCD/MVAs had more frequently an arrhythmogenic profile and a larger left atrium. Their LVEF at the last available evaluation before the arrhythmic event was 36 ± 12%. At multivariable analysis, left atrial end-systolic area [hazard ratio 1.107; 95% confidence interval (95% CI) 1.039–1.179, P = 0.002 for 1 mm2 increase] and arrhythmogenic profile (hazard ratio 3.667; 95% CI 1.762–7.632, P = 0.001) emerged as predictors of SCD/MVAs during follow-up.

Conclusion

A consistent quota of DCM patients with intermediate left ventricular dysfunction receiving OMT experienced SCD/MVA during follow-up. Left atrial dilatation and arrhythmogenic pattern were associated with a higher risk of SCD/MVA.
Transdermal patches: Design and current approaches to painless drug delivery
Authors: Al Hanbali Othman A. , Khan Haji Muhammad Shoaib , Sarfraz Muhammad , Arafat Mosab , Ijaz Shakeel , Hameed Abdul
Published: April 2019

Use of transdermal patches can evade many issues associated with oral drug delivery, such as first-pass hepatic metabolism, enzymatic digestion attack, drug hydrolysis and degradation in acidic media, drug fluctuations, and gastrointestinal irritation. This article reviews various transdermal patches available in the market, types, structural components, polymer role, and the required assessment tools. Although transdermal patches have medical applications for smoking cessation, pain relief, osteoporosis, contraception, motion sickness, angina pectoris, and cardiac disorders, advances in formulation development are ongoing to make transdermal patches capable of delivering more challenging drugs. Transdermal patches can be tailored and developed according to the physicochemical properties of active and inactive components, and applicability for long-term use. Therefore, a number of chemical approaches and physical techniques for transdermal patch development are under investigation.
The Value of Integrating 21st Century Skills into the Enterprise of Teaching Sociology
Authors: Nnebedum Chigozie
Published: April 2019

The 21st Century labour market is changing fast with unprecedented acceleration. Training in the field of sociology follows the pattern of education which is a process of leading out of ignorance and bringing one up to another plain, a higher one, within a societal context. Its organisation and curricular should be done within the frame work of the general society and life. It ought to follow the trend of the time. This article discusses the discipline of sociology, its concept and teaching approach from the ambiance of integrating 21st century skills into it. Using the qualitative method, the article examines the study of sociology in the light of the 21st Century, and reveals that students will be confronted with the effects social institutions, globalization, and technological advancement have on education in general. In responding to this challenge, the article reveals that sociology, through studies and statistical research across societies, will be able to establish that the more technical skills and knowledge one gains, the easier it is to move up to the upper class in the society (Max Weber). As a study of social life, sociology adapts and allows its fields to be re-structured to meet up with the demands of the “ever-changing” social life. Since the world in the 21st century has experienced technological and social developments and challenges, which have many impacts on the lives of individuals living in it, the teaching of sociology has to be abreast with the demands of the current century.
Market Regulation and Marketing of Enterprises as a Factor for the Development of SMEs in Kosovo
Authors: Ukaj Fatos , Bibuljica Husnija
Published: April 2019

Based on observation, enterprises are an economic organization established to make a profit. On the other hand, marketers are responsible for ensuring customer’s satisfaction. This is done firstly by increasing the growth of sales which will bring good business results. To reconcile these two approaches, we have to distinguish what entrepreneurs that run SMEs do. The environment has a significant influence on the development of SMEs. Furthermore, we consider the Legal issues and Legislation as the main factor that will let SMEs satisfy customer needs and generate profits. Also, we conducted field research where we used survey questionnaire as an instrument for data collection. Based on the findings of this study, we drew out conclusions and recommendations that will be useful for the future treatment of SMEs, and as a real force of the economic development of a country. All this, therefore, should be based on marketing concept requirements and appropriate legislation as support and insurance for investments made.
Ontology–based access to temporal data with Ontop: A framework proposal
Authors: Güzel Kalayci Elem , Brandt Sebastian , Calvanese Diego , Ryzhikov Vladislav , Xiao Guohui , Zakharyaschev Michael
Published: April 2019

Predictive analysis gradually gains importance in industry. For instance, service engineers at Siemens diagnostic centres unveil hidden knowledge in huge amounts of historical sensor data and use it to improve the predictive systems analysing live data. Currently, the analysis is usually done using data-dependent rules that are specific to individual sensors and equipment. This dependence poses significant challenges in rule authoring, reuse, and maintenance by engineers. One solution to this problem is to employ ontology-based data access (OBDA), which provides a conceptual view of data via an ontology. However, classical OBDA systems do not support access to temporal data and reasoning over it. To address this issue, we propose a framework for temporal OBDA. In this framework, we use extended mapping languages to extract information about temporal events in the RDF format, classical ontology and rule languages to reflect static information, as well as a temporal rule language to describe events. We also propose a SPARQL-based query language for retrieving temporal information and, finally, an architecture of system implementation extending the state-of-the-art OBDA platform Ontop.
Prevalence of anaemia and associated factors among Oraon females of North 24 Parganas, West Bengal, India
Authors: Kundu Chowdhury Tanaya , Roy Subrata K.
Published: April 2019

Low haemoglobin level or anaemia is a health problem worldwide especially in developing countries like India. Anaemia is generally higher among indigenous groups compared to general population globally and females are specifically more prone to anaemia. However, studies are inadequate on indigenous groups of India. The aims of the study are to determine the prevalence of anaemia among the female Oraons of North 24 Parganas and to study the association between anaemia and concomitants like socio-demographic and food habit variables. Data have been collected on demographic, socio-economic and food habit variables using well-tested questionnaire from 309 Oraon females living in rural and urban areas of North 24 Parganas, West Bengal. Haemoglobin data were collected using standard instrument and technique. Descriptive statistics and binary logistic regression were used to analyze the data using SPSS version 16.0. Females of rural and urban areas were mostly married and non-literate, employed as labourers and had sedentary occupations. Majority of them consume fruits and vegetables but less animal protein and dairy product. Around 80% of the females were anaemic, irrespective of their habitat, socio-economic status and food habits. Anaemic status was associated with insufficient intake of animal protein, which is significantly associated with the anaemia status of the females in the present study.
A novel de novo paracentric inversion [inv(20)(q13.1q13.3)] accompanied by an 11q14.3-q21 microdeletion in a pediatric patient with an intellectual disability
Authors: Zachaki S , Kouvidi E , Mitrakos A , Lazaros L , Pantou A , Mavrou A , Tzetis M , Manola KN
Published: April 2019

A novel de novo paracentric inversion of the long arm of chromosome 20 [inv(20)(q13.1q13.3)], detected by conventional karyotyping in a 14-year-old boy with mental retardation is described. Further investigation by array comparative genomic hybridization (aCGH) revealed that the 20q inversion was not accompanied by microdeletions/microduplications containing disease-associated genes near or at the breakpoints. Two deletions at chromosomal regions 11q14.3q21 and 20q12 of 4.5 and 1.97 Mb size, respectively, containing important online Mendelian inheritance in man (OMIM) genes, were detected. The 4.5Mb 11q14.3q21 microdeletion was contained within a region that is involved, in most of the reported cases, with the interstitial 11q deletion and may be related to the mental retardation and developmental delay present in the patient. On the other hand, the published data about the 20q12 microdeletion are very few and it is not possible to correlate this finding with our patient’s phenotype. This case report contributes to the description of a new chromosomal entity, not previously reported, and is therefore important, especially in prenatal diagnosis and management of patients. Array comparative genomic hybridization has proven a useful technique for detecting submicroscopic rearrangements and should be offered prenatally, especially in cases of de novo karyotypically balanced chromosomal inversions or translocations in order to unveil other unbalanced chromosomal abnormalities such as deletions and amplifications.
The role of next generation sequencing in the differential diagnosis of caroli’s syndrome
Authors: Smolović B , Muhović D , Hodžić A , Bergant G , Peterlin B
Published: April 2019

We report the case of a 41-year-old man on conservative treatment for more than 20 years for chronic renal insufficiency, chronic hepatitis and recurrent cholangitis. Following lengthy and extensive diagnostics, the differential diagnosis included primary sclerosing cholangitis and Caroli’s disease (CD). To solve the diagnostic challenge, next generation sequencing (NGS) was performed to distinguish between the disorders possibly present in the patient. The diagnosis of CD became evident after two rare known pathogenic mutations were detected in the poly-ductin 1 (PKHD1) gene, c.370C>T (p.Arg124Ter) and c.4870C>T (p.Arg1624Trp). In this case, NGS was instrumental in solving the diagnostic challenge, allowing differentiation among the proposed genetic and non-genetic ethiologies.
A Review of Feature Selection and Its Methods
Authors: Venkatesh B. , Anuradha J.
Published: April 2019

Nowadays, being in digital era the data generated by various applications are increasing drastically both row-wise and column wise; this creates a bottleneck for analytics and also increases the burden of machine learning algorithms that work for pattern recognition. This cause of dimensionality can be handled through reduction techniques. The Dimensionality Reduction (DR) can be handled in two ways namely Feature Selection (FS) and Feature Extraction (FE). This paper focuses on a survey of feature selection methods, from this extensive survey we can conclude that most of the FS methods use static data. However, after the emergence of IoT and web-based applications, the data are generated dynamically and grow in a fast rate, so it is likely to have noisy data, it also hinders the performance of the algorithm. With the increase in the size of the data set, the scalability of the FS methods becomes jeopardized. So the existing DR algorithms do not address the issues with the dynamic data. Using FS methods not only reduces the burden of the data but also avoids overfitting of the model.
Hybrid Recommender System via Personalized Users’ Context
Authors: Nosshi Anthony , Asem Aziza , Senousy Mohamed Badr
Published: April 2019

In movie domain, finding the appropriate movie to watch is a challenging task. This paper proposes a recommender system that suggests movies in cinema that fit the user’s available time, location, mood and emotions. Conducted experiments for evaluation showed that the proposed method outperforms the other baselines.
Establishing a Business in Ukraine – the Initial Regulatory Organizational and Legal Aspects for Polish Entrepreneurs
Authors: Glinkowska Beata , Chebotarov Viacheslav
Published: April 2019

The inspiration to create this summary was research carried out on the Polish–Ukrainian internationalization of business activity conditions and their models. The article contains conclusions based on the authors’ interviews with Ukrainian businessmen and government officials, as well as an analysis of legal acts related to establishing a business in Ukraine by members of the Polish business community. A reference to fundamental regulations is presented. The research shows that serious legal easements for starting a business in Ukraine have occurred. This is the first step towards building a positive atmosphere. However, there are many factors which often discourage Polish entrepreneurs to initiate foreign expansion towards Ukraine and, on this basis, beyond its borders. The governments of both countries should pay attention to them. In this context, the article contains initial provisions for improving the legislative base of Ukraine in the field of internationalization. For Polish entrepreneurs, the basic recommendations for establishing a business in Ukraine are justified.
Surface temperature of plant tissues. Which method of air temperature measurement fits best?
Authors: Litschmann Tomáš , Středa Tomáš
Published: April 2019

Climate change is contributing to an increased risk of flower damage by late spring frosts. Monitoring flower temperature is critical for the timely start of frost protection systems. However, there are many weak points that complicate the use of this method. The aims of this study were to: i) find the method of air temperature measurement with the best relationship to the surface temperature of plant tissues and ii) quantify the differences between plant tissues surface temperature and ambient temperature during different weather situations. The surface temperature of plant tissues (budding leaves of grapevine, apricot flower, and unripe pear fruit), air temperature and humidity in the radiation shield, wet bulb temperature and air temperature with an unsheltered thermometer were measured at ten-minute intervals in the spring months. The average temperatures obtained by the individual methods as well as the lowest temperatures were determined from each measurement. Differences between air temperatures and plant surface temperatures, including variation ranges, were also determined. An unsheltered thermometer, in which the energy balance corresponds approximately to that of the evaluated plant surfaces, provided the best relationship with plant tissue temperature. The air temperature measured by the standard method (in a Stevenson screen or in the radiation shield) was almost always higher than the temperature of the plant tissue during periods of negative energy balance. The difference between the minimum temperatures was approximately 0.5 °C. Temperatures more than 1.5 °C higher than the actual temperature of plant tissues were measured in extreme cases.
Evidences of the charge fundamental asymmetry
Authors: Lutephy Mohsen
Published: April 2019

There is an infinitesimal small non polarizable electric inertial charge in the individual atoms or in a number neutral matter included to equal number of the electrons and protons. We refer to the pure calculations verified by the experimental laboratorial results, also planetary phenomena and cosmic observations. This inertial electric charge is origin of a part of the measurable magnetic field in addition to self-consistent dynamo, together as complementary origins to generate very complex magnetism of the celestial bodies. Ultimately we refer to the null results of the test experiments for the spinning bodies magnetic field and we see that neither used bodies in the experiments have been number neutral (no equal number of the electrons and protons), nor the simple formula of the Patrick Blackett is accurate in detail. But we have extracted a new formula in agreement for all spinning bodies magnetic fields, in agreement with both terrestrial and cosmic bodies. We verify the effect of electric charge asymmetry in expanding universe and acceleration of the universe expansion and anisotropy of cosmic microwave background and singularity paradox and solar wind and acceleration of solar wind and corona high temperature puzzle as an equilibrium between the gravity and antigravity and mysterious heat generation of the Sun and planets interiors and missing neutrino and the comets plasma tail outward direction and pendulums mysterious precessions and some other mysteries phenomena too.