bluuebunny/crossref_metadata_2025 huggingface dataset:
MicroRNA-126-5p Regulates Proliferation and Apoptosis of IL-22-Stimulated Human Keratinocytes Through Regulating Caspase 1
Authors: Zha Weifeng , Guo Bo , Chen Shuyue , Lu Junwei , Shan Yunyun
Published: June 2021

Objective: The study was aimed to explore the roles of miR-126-5p in psoriasis and the underlying molecular mechanisms. Methods: In vitro cell model of psoriasis was established by IL-22 induction. CASP1, the target gene of miR-126-5p, was predicted by TargetScan and verified
through the dual luciferase reporter gene system. qRT-PCR was used to measure the mRNA expression of miR-126-5p and CASP1 in IL-22 stimulated HaCaT cells. The protein expression of CASP1, cleaved-caspase3 and caspase3 were measured by Western blot analysis. MTT assay and flow cytometry analysis
were performed to detect the cell proliferation and apoptosis. A Caspase3 Activity Assay kit was used to detect the activity of Caspase3. Results: miR-126-5p was high expressed in IL-22 stimulated HaCaT cells compared with normal HaCaT cells. We predicted and verified that CASP1 was
a direct target of miR-126-5p, and the mRNA and protein expression of CASP1 were reduced in IL-22 stimulated HaCaT cells compared with the normal HaCaT cells. miR-126-5p inhibitor and CASP1-siRNA significantly decreased the expression of miR-126-5p and CASP1 in HaCaT cells respectively. miR-126-5p
inhibitor up-regulated the expression of CASP1 in HaCaT cells, and the effect was reversed by the transfection with CASP1-siRNA. In comparison with the control group, miR-126-5p inhibitor decreased the cell proliferation, induced apoptosis, and improved the activity of Caspase3, enhanced cleaved-caspase3/caspase3
ratio in IL-22 stimulated HaCaT cells, and all the effects were reversed by down-regulating CASP1. Conclusion: We demonstrated that miR-126-5p inhibitor played a protective role in psoriasis by targeting CASP1, evidenced by inhibiting IL-22-induced HaCaT cell proliferation and inducing
apoptosis.
Expression of Vascular Endothelial Growth Factor, Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Polycystic Ovarian Syndrome Rats and Its Implication
Authors: Li Wei , Zhang Yufang , Li Fuping , Shi Yufen , Wang Yan
Published: June 2021

Polycystic ovary syndrome (PCOS) is a female endocrine disorder and frequently leads to infertility. Vascular endothelial growth factor (VEGF) has crucial roles and matrix metalloproteinase (MMPs) is correlated with cell migration. Both of them are involved in the occurrence and progression
of PCOS. This study established a rat PCOS model using letrozole to measure the expression of VEGF, MMP-2 and MMP-9 (MMP-2/9), to analyze its correlation with PCOS. Letrozole was applied by gavage to establish rat PCOS model. General condition and ovarian tissue morphology were observed under
a light field microscope. ELISA and immunohistochemistry (IHC) were used to detect serum or tissue expression of VEGF, MMP-2/9. Estrous cycle of rats was disrupted after 12 d for using letrozole. Vaginal smear showed abundant leukocytes with sparse keratinocytes. Ovary showed whitening and
increased volume, with early phase small follicles plus lower granular cells or corpus luteum. Compared to control group, experimental group had significantly higher VEGF, MMP-2/9 (P < 0.05), which were higher in antral follicles than those in preantral follicle with higher expressions
than primordial follicle (P < 0.05). In conclusion, VEGF, MMP-2/9 are abundantly expressed in both serum and tissues of PCOS rats.
S-1 and Capecitabine for the Treatment of Colorectal Cancer: A Meta-Analysis
Authors: Huang Ping , Wang Zhenfen , Liu Qian , Cai Guohao
Published: June 2021

Colorectal cancers common tumors that develop in the large intestines. The incidence of colorectal cancer is second only to gastric and esophageal cancers. Both S-1 and capecitabine are the third-generation fluorouracil-based chemotherapeutic drugs. We hope to summarize the therapeutic
effects of tecotae and capecitabine in patients with colorectal cancer through this Meta-analysis. We performed a meta-analysis of the findings in the current literature. We performed a systematic review of outcomes associated with S-1 and capecitabine used to treat advanced colorectal cancer
based on findings from both English and Chinese publications listed in PubMed, Embase, CNKI, Wanfang, EBSCO, Web of Science and the Cochrane Library. End-points included ORR, DCR, OS, and PFS; adverse events (grades 1–2 and 3–4) were also evaluated. Statistical analysis was performed
using RevMan 5.3. A total of 12 studies were eventually included, involving a total of 3,375 patients. Of this group, 1,683 and 1,692 patients underwent treatment with S-1 or capecitabine, respectively. There were no greatly differences with respect to ORR, DCR, or OS; however, PFS was bettered
in the group of S-1 compared to those treated with capecitabine. The incidence of leukopenia, diarrhea and anorexia were all higher among those in S-1 group compared to the capecitabine group, but a higher incidence of hand-foot syndrome was linked with use of capecitabine. Use of S-1 for
the treatment of colorectal cancer may result in superior outcomes when compared to use of capecitabine.
Effects of Different Concentrations of Transforming Growth Factor β_1 (TGF-β_1) on the Number and Transdifferentiation of Endometrial Epithelial Cells in Endometrial Tissue
Authors: Li Zhiying , Li Junjiao , Li Minqiang , Cai Ansheng , Liu Hong , Miao Huoying , Shan Tieying , Ma Jinghong
Published: June 2021

To study the influence of different concentrations of TGF-β_1 on the number and transdifferentiation of epithelial cells in endometrial tissue. 40 cases of normal endometrial tissue obtained by surgery in our hospital were collected, and epithelial cells were separated.
According to the random number table method, cells were assigned into normal control groups (only with culture solution) and experimental groups (TGF-β1 was added on the basis of the above), the experimental group is further assigned into three groups, that is, low-dose (3 ng/ml),
medium-dose (6 ng/ml) and high-dose (9 ng/ml) TGF-β_1 group followed by analysis of cell numbers, FN, α-SMA and Col-I level. FN secretion in normal control group was (0.469±0.010) ng/L, and ColI secretion was (0.532±0.033) ng/L. There was a difference
between FN values and Col-I values in each experimental group (P < 0.01); α-SMA and other data in the experimental group had opposite effects compared with control group with significant differences for different concentrations of TGF-β_1. As concentration
gradually increased, E-cadherin level in cytoplasm will gradually decrease. On the contrary, α-SMA level in cytoplasm will gradually increase (P < 0.05) (F = 145.125, 179.511, P < 0.01). TGF-β_1 stimulates the increase in of number of epithelial
cells in endometrial tissue and induces them to transform into myofibroblasts dose dependently
Del Convivio e del perché Bartolo da Sassoferrato non lo conoscesse
Authors: Di Fonzo Claudia
Published: June 2021

Il contributo porta avanti l’analisi della repetitio alla lex si ut proponitis del dodicesimo libro del Codice del giurista Bartolo da Sassoferrato dedicata alla dignitas e alla nobilitas. Si dimostra, con elementi interni al testo, che Bartolo conosceva la canzone Le dolci rime d’amore ch’io solea, che commenta minuziosamente nel suo approfondimento giuridico (repetitio), ma che non conosceva il Convivio. Giunto a discutere la seconda delle opiniones in materia di nobiltà che Dante espone nella canzone Le dolci rime, Bartolo interpreta erroneamente il verso che recita “e altri fue di più lieve savere / che tal detto rivolse / e l’ultima particula ne tolse” dimostrando di non conoscere l’auto-commento che Dante fa della canzone medesima nel quarto libro del Convivio. Il volgarizzamento procurato da Lapo da Castiglionchio nella seconda metà del Trecento, fedelissimo al dettato latino della repetitio ci fornisce una controprova di questa posizione critica.
No, No One Had Fun. Individual Differences in Nonliteral Language Perception
Authors: Joergensen Gitte Henssel , Makarla Pavitra Rao , Fammartino Matthew , Benson Lauren , Rothermich Kathrin
Published: June 2021

Nonliteral language represents a complex form of communication that can be interpreted in numerous different ways. Our study explored how individual differences in personality and communication styles affect the evaluation of literal and nonliteral language in the context of assumptions made by the Tinge Hypothesis (Dews & Winner, 1995). Participants watched videos of social interactions focusing on positive, negative, sarcastic, and jocular statements. They evaluated speaker intentions and social impressions and completed several personality and communication style questionnaires. Individual differences in empathy, defense style, and sarcasm use correlated with the accuracy of identifying speaker intent. Additionally, positive statements were rated as friendlier when compared to jocular statements, thereby supporting the Tinge Hypothesis. However, literal negative statements were rated as more friendly than sarcastic statements, which is inconsistent with the Tinge Hypothesis. The current results provide novel evidence for the Tinge Hypothesis using multimodal, dynamic stimuli and highlight the role of the individual personality of the recipient in evaluating sarcasm and jocularity.
The silent inquisition: Islamophobic microaggressions and Spanish Moroccan identity negotiations in contemporary Madrid
Authors: Ouassini Anwar
Published: June 2021

This article explores Spanish Moroccan experiences with Islamophobic microaggressions in contemporary Madrid. It seeks to fill an important gap in the literature on religion and racial microaggressions by moving beyond the usual psychologistic explanations to show how these acts reflect Spanish historical-racialized structures, where Muslims were regarded as the Other. In utilizing in-depth qualitative interviews and participant observations, the author reveals how Spanish Moroccans are negotiating and responding to Islamophobic microaggressions at work, educational institutions, and the public sphere. Ultimately, this research shows how these microaggressions reinforced a Muslim-first identity framework, which allowed them to strategically link their experiences and identities to a collective, historical memory of Muslim Spain.
A Systematic Review and Meta-Analysis of Patient Decision Aids for Socially Disadvantaged Populations: Update from the International Patient Decision Aid Standards (IPDAS)
Authors: Yen Renata W. , Smith Jenna , Engel Jaclyn , Muscat Danielle Marie , Smith Sian K. , Mancini Julien , Perestelo-Pérez Lilisbeth , Elwyn Glyn , O’Malley A. James , Leyenaar JoAnna K. , Mac Olivia , Cadet Tamara , Giguere Anik , Housten Ashley J. , Langford Aisha , McCaffery Kirsten , Durand Marie-Anne
Published: June 2021

Background

The effectiveness of patient decision aids (PtDAs) and other shared decision-making (SDM) interventions for socially disadvantaged populations has not been well studied.

Purpose

To assess whether PtDAs and other SDM interventions improve outcomes or decrease health inequalities among socially disadvantaged populations and determine the critical features of successful interventions.

Data Sources

MEDLINE, CINAHL, Cochrane, PsycINFO, and Web of Science from inception to October 2019. Cochrane systematic reviews on PtDAs.

Study Selection

Randomized controlled trials of PtDAs and SDM interventions that included socially disadvantaged populations.

Data Extraction

Independent double data extraction using a standardized form and the Template for Intervention Description and Replication checklist.

Data Synthesis

Twenty-five PtDA and 13 other SDM intervention trials met our inclusion criteria. Compared with usual care, PtDAs improved knowledge (mean difference = 13.91, 95% confidence interval [CI] 9.01, 18.82 [I2 = 96%]) and patient-clinician communication (relative risk = 1.62, 95% CI 1.42, 1.84 [I2 = 0%]). PtDAs reduced decisional conflict (mean difference = −9.59; 95% CI −18.94, −0.24 [I2 = 84%]) and the proportion undecided (relative risk = 0.39; 95% CI 0.28, 0.53 [I2 = 75%]). PtDAs did not affect anxiety (standardized mean difference = 0.02, 95% CI −0.22, 0.26 [I2 = 70%]). Only 1 trial looked at clinical outcomes (hemoglobin A1C). Five of the 12 PtDA studies that compared outcomes by disadvantaged standing found that outcomes improved more for socially disadvantaged participants. No evidence indicated which intervention characteristics were most effective. Results were similar for SDM intervention trials.

Limitations

Sixteen PtDA studies had an overall unclear risk of bias. Heterogeneity was high for most outcomes. Most studies only had short-term follow-up.

Conclusions

PtDAs led to better outcomes among socially disadvantaged populations but did not reduce health inequalities. We could not determine which intervention features were most effective. [Box: see text]
Instability of the printing jet during the three-dimensional-printing process
Authors: Zuo Yuting , Liu Hongjun
Published: June 2021

Euler’s instability criterion is widely used in engineering to design a column. However, this criterion is not suitable for judging the instability of a three-dimensional printing process because the axial motion of the printing jet has to be considered. A variational principle is established, and an equivalent Eulerian load is obtained. The theoretical results show that a higher printing velocity makes the moving jet much more stable, and an experiment is designed to verify our theoretical prediction.
APKASS Consensus Statement on Chronic Syndesmosis Injury, Part 2: Indications for Surgical Treatment, Arthroscopic or Open Debridement, and Reconstruction Techniques of Suture Button and Screw Fixation
Authors: Kurokawa Hiroaki , Li Hongyun , Angthong Chayanin , Tanaka Yasuhito , Song Yujie , Shi Zhongmin , Ling Samuel K.K. , Yung Patrick , Han Seung Hwan , Hua Yinghui , Jiao Chen , Gui Jianchao , Li Qi
Published: June 2021

Background:

The indications for surgical treatment of chronic syndesmosis injury are challenging for many orthopaedic clinicians, as there is no international consensus on the optimal management of these injuries.

Purpose:

An international group of experts representing the field of sports injuries in the foot and ankle area was invited to collaboratively advance toward consensus opinions based on the best available evidence regarding chronic syndesmosis injury. All were members of the Asia-Pacific Knee, Arthroscopy and Sports Medicine Society (APKASS).

Study Design:

Consensus statement.

Methods:

From November to December 2020, a total of 111 international experts on sports medicine or ankle surgery participated in a 2-stage Delphi process that included an anonymous online survey and an online meeting. A total of 13 items with 38 statements were drafted by 13 core authors. Of these, 9 items with 17 clinical questions and statements were related to indications for surgical treatment, arthroscopic versus open debridement, and suture button versus screw fixation reconstruction techniques and are presented here. Each statement was individually presented and discussed, followed by a general vote. The strength of consensus was characterized as follows: consensus, 51% to 74%; strong consensus, 75% to 99%; and unanimous, 100%.

Results:

Of the 17 questions and statements, 4 achieved unanimous support, 11 reached strong consensus, and 2 reached consensus.

Conclusion:

This APKASS consensus statement, developed by international experts in the field, will assist surgeons and physical therapists with surgical indications and techniques for chronic syndesmosis injury.
Digital technologies to support people living with dementia in the care home setting to engage in meaningful occupations: protocol for a scoping review
Authors: Luscombe Nicholas , Morgan-Trimmer Sarah , Savage Sharon , Allan Louise
Published: June 2021

Background

People living with all stages of dementia should have the opportunity to participate in meaningful occupations. For those living in care homes, this may not always occur and residents may spend significant parts of the day unengaged, especially those living with more advanced dementia. Digital technologies are increasingly being used in health care and could provide opportunities for people living with dementia (PLWD) in care homes to engage in meaningful occupations and support care staff to provide these activities. With technology advancing at a rapid rate, the objective of this scoping review is to provide an up-to-date systematic map of the research on the diverse range of digital technologies that support engagement in meaningful occupations. In particular, focus will be given to barriers and facilitators to inform future intervention design and implementation strategies, which have not yet been clearly mapped across the full range of these digital technologies.

Method

A scoping review will be conducted to systematically search for published research using a comprehensive search strategy on thirteen databases. Published, peer-reviewed studies that focused on PLWD in the care home setting and assessed any form of digital technology that supported a meaningful occupation will be included. All methodologies which meet the criteria will be included. Data will be extracted and charted to report the range of digital technologies, underlying mechanisms of action, facilitators and barriers to implementation.

Discussion

Mapping the range of technologies to support PLWD to engage in meaningful occupations will identify gaps in research. The systematic search will include a diverse range of technologies such as software to enhance care planning, tablets devices, smartphones, communication robots and social media platforms, rather than focussing on a specific design or interface. This will enable comparison between mechanisms of action, barriers and facilitators to implementation which will be useful for future research and intervention design.

Trial registration

Open Science Framework 10.17605/OSF.IO/7UDM2
The effects of neoadjuvant chemoradiotherapy and an in-hospital exercise training programme on physical fitness and quality of life in locally advanced rectal cancer patients: a randomised controlled trial (The EMPOWER Trial)
Authors: Loughney Lisa , West Malcolm A. , Moyses Helen , Bates Andrew , Kemp Graham J. , Hawkins Lesley , Varkonyi-Sepp Judit , Burke Shaunna , Barben Christopher P. , Calverley Peter M. , Cox Trevor , Palmer Daniel H. , Mythen Michael G. , Grocott Michael P. W. , Jack Sandy ,   on behalf of the Fit4Surgery group
Published: June 2021

Background

The EMPOWER trial aimed to assess the effects of a 9-week exercise prehabilitation programme on physical fitness compared with a usual care control group. Secondary aims were to investigate the effect of (1) the exercise prehabilitation programme on psychological health; and (2) neoadjuvant chemoradiotherapy (NCRT) on physical fitness and psychological health.

Methods

Between October 2013 and December 2016, adults with locally advanced rectal cancer undergoing standardised NCRT and surgery were recruited to a multi-centre trial. Patients underwent cardiopulmonary exercise testing (CPET) and completed HRQoL questionnaires (EORTC-QLQ-C30 and EQ-5D-5L) pre-NCRT and post-NCRT (week 0/baseline). At week 0, patients were randomised to exercise prehabilitation or usual care (no intervention). CPET and HRQoL questionnaires were assessed at week 0, 3, 6 and 9, whilst semi-structured interviews were assessed at week 0 and week 9. Changes in oxygen uptake at anaerobic threshold (VO2 at AT (ml kg−1 min−1)) between groups were compared using linear mixed modelling.

Results

Thirty-eight patients were recruited, mean age 64 (10.4) years. Of the 38 patients, 33 were randomised: 16 to usual care and 17 to exercise prehabilitation (26 males and 7 females). Exercise prehabilitation significantly improved VO2 at AT at week 9 compared to the usual care. The change from baseline to week 9, when adjusted for baseline, between the randomised groups was + 2.9 ml kg −1 min −1; (95% CI 0.8 to 5.1), p = 0.011.

Conclusion

A 9-week exercise prehabilitation programme significantly improved fitness following NCRT. These findings have informed the WesFit trial (NCT03509428) which is investigating the effects of community-based multimodal prehabilitation before cancer surgery.

Trial registration

ClinicalTrials.gov NCT01914068. Registered 1 August 2013.
Milo Rau as Influencer
Authors: Kraft Helga
Published: June 2021

Helen Kraft considers director Milo Rau as an influencer. Kraft places Rau within a subcategory of influencer identified by economist and psychologist Robert Cialdini as intellectuals who are “well-connected, create an impact, have active minds, and are trendsetters.” She argues that Rau fills that role in the theater and positions the director in relation to other postmodern thinkers and theater artists. According to Kraft, Rau actively courts controversy with his work as a means of drawing attention to conflict and corruption around the world, but, despite frequent comparisons to Bertolt Brecht, Rau is not an idealogue, exposing inconsistencies rather than promoting any single ideology in his work.
Play with Consequences?
Authors: Englhart Andreas
Published: June 2021

Andreas Englhart examines the aesthetics of evil, particularly extreme evil, in the work of director Milo Rau, focusing on Five Easy Pieces. Englhart considers the ways in which postmodern aesthetics are beginning to turn once again toward the ethical and how this turn is both reflected and problematized in Rau’s “theater of the real.” The analysis includes aesthetic consideration, an examination of Rau’s rehearsal and creation techniques, and the ways in which audiences and critics have responded to these provocations in different performances.
Influence of representation of social space on psychological adaptation to police service
Authors: Popinako Ekaterina , Zlokazov Kirill , Sitnikov Valeriy
Published: June 2021

The article studies police officers' perceptions of other people, analyzes the change in these perceptions during adaptation to service during on the period of training for the profession of "Policeman". The article described the influence of perceptions of social space on adaptation in officers first hired into the internal affairs service. In addition, the influence of this perception on the prospects of service in the police was studied.

The method of collecting information was a standardized self-report, studying the qualities and properties of the representation of the social space. The study involved 219 police officers.

As a result, it was found that at the beginning of professional training employees who plan to continue their service in police are characterized by a wider range of social interaction, which remains throughout the training. These employees feel support from different social groups. Employees who are not motivated to continue their professional activities in police have no changes in the representation of the properties of social interaction, but by the end of training there is an increase in the quality of interaction, consisting in the manifestation of a more responsible attitude to the close social environment. These employees perceive the social space as impeding and hindering further professional development. The analysis of qualities and properties of employees' social space in the future can contribute to the improvement of psychological work on adaptation of employees to the conditions of educational and service activity during the period of professional training.
Development of professional adaptation of employees of internal affairs bodies at the stage of vocational training
Authors: Garmanova Ol'ga , Deryagina Larisa
Published: June 2021

The article examines the content of professional adaptation of employees of internal affairs bodies, as well as the reasons that complicate their adaptation. Using a systematic approach to the study of professional activity, a number of features of adaptation of employees at the stage of training in the main vocational training programs are revealed. In particular, it emphasizes the importance of studying the formation of a student's own ideas in the educational organization of the Ministry of Internal Affairs of Russia about the profession of an employee of internal affairs bodies at the early stages of professional development. By them, the article proposes to un-derstand: 1) the very first stage of recruitment (including during the period of the beginning of training in the system of professional training in the main vocational training programs); 2) the process of vocational training (including prior to its completion); 3) completion of vocational training and independent performance of official duties by employees of the internal affairs bodies who have undergone professional training. The article proposes specific ways of creating conditions for professional adaptation of students of vocational training. It is concluded that the study of the indicated issue will strengthen the human resources of the internal affairs bodies, form professionally significant qualities of the employees of the internal affairs bodies, and also increase the efficiency of their activities.
Craft education as a perspective direction of development of modern professional education
Authors: Kumohin Aleksandr , Antonovskiy Aleksandr
Published: June 2021

The article considers the main aspects of craft activity in modern society and reviews the literature on craft education as one of the directions of development and improvement of professional education. The main organizational, technological and psychological characteristics of handicraft activity are highlighted. The analysis of trends in the development of professional work in the context of providing professional training for handicraft business is carried out. The main problematic areas of handicraft activity are noted: the lack of legislative and regulatory documents regulating the field of handicraft; federal state educational standards in the field of training of handicraft personnel have not been developed in vocational education; professional standards have not yet been developed for existing handicraft professions and craft activities; the lack of educational and scientific literature on handicraft activities and craft professions, which limits the opportunity to master craft education. Currently, the development of handicrafts is on the path of complicating the performance of professional activities. Modern craft education requires significant intellectual investment associated with the idea and design of future products, the presence of imagination and creativity in their work, an important role is played by the ability to build and maintain interpersonal relationships with various groups of people involved in the structure of the organization of a craft enterprise. Today, the organization of handicraft work requires a certain professional training with the need to form professional competencies of various directions (technological, legal, economic, pedagogical, aesthetic, etc.), which, in turn, will be able to stimulate professional improvement and professional development in handicraft activities.
Research of psychological stability of the employees of the penal system to the influence of destructive factors of professional activity
Authors: Mikhaylov Aleksey , Pivovarova Tat'yana , Kurkova Ekaterina
Published: June 2021

The article presents the results of an empirical study of employees of the penitentiary system, the purpose of which was to study their psychological resistance to the impact of destructive factors of professional activity and the development of a psychocorrectional program. The professional activity of employees of the penal system is associated with the impact of various kinds of stress factors, the main of which is interaction with convicts with different levels of psychological and pedagogical neglect and criminal infection, which leaves an imprint on the employee's personality and destructive changes, and therefore the study the psychological stability of the penitentiary system employees to the impact of destructive factors of professional activity is of particular relevance for the penitentiary department. Having studied the psychological characteristics of employees and determined the destructive factors of professional activity, the authors checked the presence of a statistical relationship between the studied phenomena using Spearman's correlation coefficient, which made it possible to develop a psychocorrectional program for psychological support of this category of employees of the penal system. Also, within the framework of the developed psychocorrectional program, the main directions of work on the prevention and correction of destructive behavior are given, which in turn will increase the efficiency of the professional activities of penitentiary officials, improve the social and psychological climate within the team, and prevent discipline among the employees of the penal system.
The main theoretical approaches to psychological counseling of children in residential care
Authors: Gorohova Irina , Filippov Mihail , Erofeeva Mariya
Published: June 2021

The article considers one of the important directions of the practical psychologist-teacher in residential institutions - psychological counseling, the problem of psychological counseling of boarding school students, specific features of counseling by a teacher-psychologist, features of the consultant's interaction with boarding school students, the content of the motivational and need-based sphere of students at all stages of their stay in this institution: during the period of adaptation of students, correction, and training, as well as during their preparation for new living conditions and practical life after graduation, a teenager, getting into the new environment of a residential institution, it faces a lot of complex problems, it has questions about almost all vital situations: family and household, material, interpersonal, labor, legal, and so on. In the case of solving any problem situations, the level of anxiety increases in the pupils, on the basis of which neurotic states can develop, psychological overstrain, which manifests itself in numerous conflicts. To prevent them objectively and to resolve any contradictions in each residential institution psychologists-teachers must be organized counseling on topical issues of activity, relations and communication between pupils, special attention in the process of psychological counseling is given to the subject of "works" adviser: behaviour, feelings and experiences of pupils, and lists in detail the difficulties and errors made by the educational psychologist in the process of psychological counseling.
Okno na świat, okno na przekład
Authors: Tabakowska Elżbieta
Published: June 2021

A Window on the World, a Window to Translation

The core of the paper is an analysis of Olga Tokarczuk’s column “Okno” (“The window”), originally commissioned by Frankfurter Allgemeine Zeitung, first published in a German translation, and subsequently rendered into English and French. Carried out within the framework of cognitive linguistics, the analysis focuses upon the role of verbs of perception in the original (Polish) text and its three translations (English, German and French). In agreement with linguists of cognitive persuasion, it is claimed that the meaning of a text resides both in the semantic content of words and in particular grammatical structures, selected and arranged in the process of construal. It is argued that the message of “Okno” is rendered through a particular sequencing of a series of verbs of perception, which taken together constitute an extended metaphor based upon the fundamental conceptual metaphor TO KNOW IS TO SEE. Therefore, an adequate translation of the text would require recognition of the structural axis and finding in the target language(s) optimum counterparts of the original verbs. As the analysis of the three translations demonstrates, this goal may be difficult to achieve for either subjective or systemic reasons.
Chlorine and Chlorinated Compounds Removal from Industrial Wastewater Discharges: A Review
Authors: Al-Hwaiti Mohammad , Abdul Aziz Hamidi , Ahmad Mohd Azmier , Al-Shawabkeh Reyad
Published: June 2021

Adsorption techniques for industrial wastewater treatment rich in heavy metals and aqueous solutions of water-soluble such as Cl−, F−, HCO3−, NO3−, SO2−4, and PO3−, often include technologies for toxicity removals. The recent advancement and technical applicability in the treatment of chlorine and chlorinated compounds from industrial wastewater are reviewed in this article. Chlorine and chlorinated compounds are among the common discharged constituents from numerous industries. They can be carcinogenic or naturally toxic and can pose issues to aquatic ecosystems and human beings. Thus, elimination of chlorides and chlorinated compounds from water or wastewater is inevitable to get rid of the problem. Several techniques are being applied for the reduction of chlorine and chlorinated compounds in water. These include biodegradation, photochemical, adsorption, chemical, electrochemical, photo-electrochemical, membrane, supercritical extraction and catalytic method. Chlorine can react with various organic and inorganic micro-pollutants. However, the potential reactivity of chlorine for specific compounds is small, and only minor variations in the structure of the parent compound are anticipated in the water treatment process under typical conditions. This paper reviews different techniques and aspects related to chlorine removal, the types of chlorine species in solution and their catalyst, chlorine fate and transport into the environment, electrochemical techniques for de-chlorination of water, kinetics, mechanisms of reduction of chlorinated compounds, and kinetics of the electrochemical reaction of chlorine compounds.

Keywords: Industrial waste, Kinetics, Wastewater, Water purification
Effect of 2,4-D and BAP on Morphological Characters and Genetic Stability of Kaffir Lime (Citrus hystrix DC.) Callus Cultures Among Generations
Authors: Tunjung Woro Anindito Sri , Widyasari Asti Fitri , Iskandar Agnes , Nurulita Alisa Julia , Sasongko Aries Bagus , Indrianto Ari , Semiarti Endang , - Maryani
Published: June 2021

Kaffir lime has medicinal properties for the treatment of many diseases. We used in vitro culture techniques to maintain quality and increase the production of active compounds in kaffir lime. The objective of this study is to determine the phenotype and genotype of kaffir lime callus cultures grown on media with the addition of 2,4-Dichlorophenoxyacetic (2,4-D) and Benzylaminopurine (BAP) on three generations (G0, G1, and G2). The callus was induced and subcultured on Murashige and Skoog medium added with 2,4-D: BAP at concentrations of 1:0.5; 2:0 and 5:0. Results showed no significant difference in callus initiation time in all treatment groups. Morphological characteristics, including color, texture, and biomass, varied among growth regulator concentrations and generation level. A high level of callus generation corresponds to a more friable texture and a more yellowish callus. Callus grown with the addition of 2,4-D and BAP 2:0 and 5:0 showed a more friable structure and yellowish color than 1:0.5. Growth regulator concentrations in each generation did not affect the callus growth curves, but the length of each phase between generations was different. The exponential phases of G1 and G2 were faster than that of G0. Despite slight differences in phenotype, the DNA profiles of callus suggest the same pattern between treatment groups, thereby indicating that our kaffir lime callus has genetic stability and that the callus can be used as raw material for medicinal purposes.

Keywords: ISSR markers, Kaffir lime callus, Generations, Genotype, Growth factor, Phenotype
Phytoextraction and nutritional quality of forages cultivated in a constructed wetland system for wastewater treatment
Authors: Silva Rubens Ribeiro da , Freitas Gilson Araújo de , Faria Alvaro José Gomes de , Carneiro Jefferson Santana da Silva , Oliveira Inádia de Jesus , Matos Antônio Teixeira de , Abrahão Walter Antônio Pereira
Published: June 2021

This study aimed to evaluate the effects of different concentrations of sodium on the phytoextraction of nutrients and nutritional quality of forages (P. purpureum Schum and C. dactylon Pers) grown in wetland system constructed for wastewater generated in cattle slaughterhouses (WGCS) treatment. The experiment was conducted in a randomized complete block design with three replications. The treatments were tested using 2 x 5 factorial scheme, as follows: two species of grass (P. purpureum Schum and C. dactylon Pers) and five concentrations of sodium in WGCS: 70, 100, 150, 200 and 250 mg L-1. The phytoextraction potential of nutrients and the nutritional quality of forages grown in pots simulating a wetland system constructed for WGCS with sodium concentrations were assessed in terms of the contents of the nutrients nitrogen, phosphorus, potassium, calcium, magnesium and sodium in leaf tissues. The accumulations of these nutrients in the produced forages were also evaluated. Both species presented different behaviors regarding their nutrient phytoextraction potentials. The nutritional quality was changed in the forages due to the cultivation in constructed wetlands. Forage C. dactylon Pers presented higher phytoextraction potential of sodium and potassium and P. purpureum Schum presented a higher nutritional quality.
Temperature dependence of the spectral properties of Yb3+/P5+/Al3+ co-doped silica fiber core glasses
Authors: Cheng Yue , Yang Qiubai , Yu Chunlei , Guo Mengting , Jiao Yan , dai Ye , Wang Shikai , Hu Lili
Published: June 2021

Yb3+/P5+/Al3+ co-doped silica fiber core glasses with different P5+/Al3+ molar ratios were prepared by the sol-gel method and modified chemical vapor deposition (MCVD) method. The absorption and fluorescence spectra were measured using a temperature range from 25°C to 200°C. Results show that both the major absorption and emission peaks of the Yb3+ ions become weaker and wider with the temperature increasing. The absorption cross sections of HYPA1 (the molar compositions of 0.2Yb2O3-2P2O5-2Al2O3-95.8SiO2) preform slices made by MCVD with a composition similar to the commercial 20/400 ytterbium-doped silica fibers (YDFs) decrease by ∼31.8% (915 nm), ∼25.3% (940 nm) and ∼41.6% (975 nm), in addition, the emission cross sections decrease by ∼32.1% (1030 nm) and ∼22.7% (1080 nm), respectively, all which indicate the decline of the laser properties with the temperature increasing of Yb3+ doped glass samples. The highest absorption peak at 975 nm of HYPA1 is blue-shifted by 0.80 nm as temperature raised from 25°C to 200°C and the absorption coefficient of the peak wavelength is reduced by nearly 5%. Additionally, the results also demonstrate that the Rabs (the ratio of σabs@975 nm/σabs@915 nm) and Rem (the ratio of σem@1030 nm/σem@1080 nm) are affected not only by the P5+/Al3+ molar ratio but also by the temperature. This work is helpful for understanding the fiber laser performance variations with the increase of the fiber core temperature due to high power operation.
CT Guided Microwave Ablation of Osteoid Osteoma – Efficacy in Alleviation of Symptoms
Authors: P. Naufal. , Thomas Rinu Susan , Varghese Lin
Published: June 2021

BACKGROUND Osteoid osteoma is a benign bone tumour which eventually undergoes spontaneous resolution but causes distress due to severe inflammatory pain and sleep loss. Major goal of ablative procedure is alleviation of symptoms. Long term follow up studies on pain remission and complications are less commonly available for microwave ablation. We wanted to assess alleviation of symptoms and long term complications in CT guided microwave ablation of osteoid osteoma. METHODS CT (Computed tomography) guided microwave ablation was performed on 10 patients referred with clinicoradiological diagnosis of osteoid osteoma and their preoperative and 6 month postoperative numerical pain scale, frequency of pain, disability and analgesic uses were compared. Subjects were between 13 and 30 years of age. RESULTS Pain scale dropped to 0 in 9 out of 10 patients. The single remaining patient had partial remission at 6 month follow up. The only complication encountered was wound site infection. All patients were free of analgesic use, disability due to pain, and sleep loss, on follow up. CONCLUSIONS Microwave ablation as an ablative procedure offers many potential benefits and appears to have good treatment response rate with minimal complications. KEY WORDS Osteoid Osteoma, Microwave Ablation, Bone, Interventional Radiology
Forest Fragmentation Shapes Resource Partitioning for Endemic Pollinators (Hymenoptera: Meliponini)
Authors: Bridget. O Bobadoye
Published: June 2021

A field study was undertaken along six diverse habitat gradients of Kenya to evaluate the occurrence and underlining drivers that shape meliponine bee species diversity. These gradients ranged from continuous forest habitats (Indigenous forests, mixed forests and exotic forest patch) representing unfragmented habitats to dispersed habitats (Mixed deciduous woodlands, Grasslands dominated by perennial grasses such as Cenchrus ciliaris, Chloris roxburghiana and Acacia dominated bush lands) representing fragmented habitats respectively.

A total of four different species of meliponine bees were encountered with Hypotrigona gribodoi being the most abundant species, followed by Meliponula ferruginea (black), Plebeina hildebrandti and Hypotrigona ruspolii in descending order. Occurrence and diversity of Hypotrigona gribodoi, Melipona ferruginea (black), Plebeina hildebrandti and Hypotrigonaruspolii was significantly influenced by the degree of fragmentation (vegetation type) and floral diversity (P = 0.0056); the mean number of colonies recorded per study site ranged from 2.3 in dispersed habitats in the lowlands to 1.0 in continuous forest landscapes in the highlands, whereas the mean population density ranged from 2.0 to 172 colonies/25 ha-transects.

The results provide substantial support to better understand interactions between habitat structure and the degree of fragmentation in linking species diversity to habitat loss.
Razjede in njihovo celjenje pri pacientih po amputaciji
Authors: Petkovšek-Gregorin Romana
Published: June 2021

Uvod: Najpogostejši vzroki, ki vplivajo na celjenje razjed pri pacientih po amputaciji, so periferna arterijska bolezen, sladkorna bolezen in kronična venska insuficienca. Namen raziskave je bil prepoznati dejavnike, ki lahko vplivajo na celjenje razjede na amputacijskem krnu.Metode: Uporabljena je bila kvantitativna neeksperimentalna raziskovalna metodologija. Izvedena je bila retrospektivna raziskava s pregledom negovalne dokumentacije o spremljanju razjede. V raziskavo je bilo vključenih 134 pacientov po amputaciji spodnjega uda z razjedo, hospitaliziranih v letu 2017. Uporabljeni sta bili opisna statistika in logistična regresija.Rezultati: Razjedo, nastalo zaradi različnih vzrokov, je imelo 134 pacientov. Ženske imajo v primerjavi v moškimi več možnosti za prisotnost razjede ob odpustu (RO = 4,8, 95 % IZ: 1–22), prav tako pacienti, ki so imeli razjedo že ob sprejemu (RO = 7,7, 95 % IZ: 3–19,2), in tisti z več kot eno razjedo (RO = 4,7, 95 % IZ: 1–22,3). Pri pacientih, ki imajo razjedo na amputacijskem krnu, imajo večjo možnost, da se bo ta do konca rehabilitacije zacelila (RO = 0,2, 95 % IZ: 0,1–0,6 p = 0,004).Diskusija in zaključek: Ugotovitve nakazujejo, da je pri ženskah večja verjetnost, da razjeda ob odpustu ne bo zaceljena, kot pri pacientih, pri katerih je bila razjeda prisotna že ob sprejemu, in pri tistih, ki imajo več razjed. Treba bi bilo izvesti raziskavo, ki bi zajela večje število pacientov. Prav tako bi bilo treba natančneje določiti parametre spremljanja.
Optimal inequalities for contact CR-submanifolds in almost contact metric manifolds
Authors: Olteanu Andreea
Published: June 2021

In [An optimal inequality for
CR-warped products in complex space forms involving
CR
δ-invariant, Internat. J. Math. 23(3) (2012)], B.-Y. Chen introduced the CR
δ-invariant for CR-submanifolds. Then, in [Two optimal inequalities for anti-holomorphic submanifolds and their applications, Taiwan. J. Math. 18 (2014), 199–217], F. R. Al-Solamy, B.-Y. Chen and S. Deshmukh proved two optimal inequalities for anti-holomorphic submanifolds in complex space forms involving the CR
δ-invariant. In this paper, we obtain optimal inequalities for this invariant for contact CR-submanifolds in almost contact metric manifolds.
Degree of independence of numbers
Authors: Rattanamoong Jittinart , Laohakosol Vichian
Published: June 2021

A new concept of independence of real numbers, called degree independence, which contains those of linear and algebraic independences, is introduced. A sufficient criterion for such independence is established based on a 1988 result of Bundschuh, which in turn makes use of a generalization of Liouville’s estimate due to Feldman in 1968. Applications to numbers represented by Cantor series and product expansions are derived.
A new notion of orthogonality involving area and length
Authors: Kundu Anirban , Bag Tarapada , Nazmul Sk.
Published: June 2021

In this paper, a space called geometric space, involving both the notions of area and length, is introduced in general setting. The interplay, between these two ideas, is studied. As a result, a new notion of orthogonality, called area-length orthogonality or A-L orthogonality, is demonstrated. It is shown that A-L orthogonality coincides with the standard notion of orthogonality for inner product spaces. Finally, it is proved that A-L orthogonality implies Birkhoff orthogonality, but not conversely.
On first countable quasitopological homotopy groups
Authors: Torabi Hamid
Published: June 2021

If q: X → Y is a quotient map, then, in general, q × q: X × X → Y × Y may fail to be a quotient map. In this paper, by reviewing the concept of homotopy groups and quotient maps, we find under which conditions the map q × q is a quotient map, where q: Ω
n
(X, x
0) → πn
(X, x
0), is the natural quotient map from the nth loop space of (X, x
0), Ω
n
(X, x
0), with compact-open topology to the quasitopological nth homotopy group πn
(X, x
0). Ultimately, using these results, we found some properties of first countable homotopy groups.
Quantum estimates in two variable forms for Simpson-type inequalities considering generalized Ψ-convex functions with applications
Authors: Chu Yu-Ming , Rauf Asia , Rashid Saima , Batool Safeera , Hamed Y. S.
Published: June 2021

This article proposes a new approach based on quantum calculus framework employing novel classes of higher order strongly generalized

Ψ

\Psi

-convex and quasi-convex functions. Certain pivotal inequalities of Simpson-type to estimate innovative variants under the

q

ˇ

1

,

q

ˇ

2

{\check{q}}_{1},{\check{q}}_{2}

-integral and derivative scheme that provides a series of variants correlate with the special Raina’s functions. Meanwhile, a

q

ˇ

1

,

q

ˇ

2

{\check{q}}_{1},{\check{q}}_{2}

-integral identity is presented, and new theorems with novel strategies are provided. As an application viewpoint, we tend to illustrate two-variable

q

ˇ

1

q

ˇ

2

{\check{q}}_{1}{\check{q}}_{2}

-integral identities and variants of Simpson-type in the sense of hypergeometric and Mittag–Leffler functions and prove the feasibility and relevance of the proposed approach. This approach is supposed to be reliable and versatile, opening up new avenues for the application of classical and quantum physics to real-world anomalies.