bluuebunny/crossref_metadata_2025 huggingface dataset:
Tri Hita Karana Perspective in Waste Disposal from a Seaweed Processing Factory Eucheuma cottonii at Jumpai Beach, Bali
Authors: Adhyaksari Riana , Tyesta ALW Lita , Maryono Maryono
Published: November 2023

The name Tri Hita Karana comes from Sanskrit: Tri means three, Hita means happiness/prosperity, and Karana means cause. Seaweed is one of the abundant natural resources of Indonesia. In the processing which can significantly affect the quality of the final product obtained. The results of this research observed effluent waste was observed to be discharged freely from a pipe exiting the rear factory wall directly onto the beach, or into the sea at high tide. This material was collected and analysed. The processing of seaweed (Eucheuma cottonii) in this factory uses ≥90% Potassium hydroxide (KOH) as a raw material (as evidenced by the numerous empty sacks of KOH 90% strewn around the site, as well as direct reports from workers). This concentrated KOH is highly hazardous and is used to boil the seaweed with water. The average of a continuous concentration in different time (three hours) of K+ detected were 1000 ppm or 1% and 939 ppm or 0.939%, while the concentration of other elements detected was Cl with an average of a continuous concentration in different time (three hours) were 759.3 ppm or 0.759% and 581 ppm or 0.581%. This indicates that this factory waste contains KOH and has the potential to pollute the environment, especially sea water and the adjacent beach ecosystem. The results showed that the pH of the waste-water was 10.34 and 9.25. This indicates an alkaline pH almost certainly due to factory processing with KOH in the factory, exceeding the ideal pH value for sea water. A high concentration of KOH will cause the pH of the waste-water to shift towards alkaline and kill marine life and poison the beach ecosystem. This is worrying as the area supports a rural population who depend on fishing for much of their livelihood. The researcher concluded that the waste-water contains KOH and has highly potential to pollute the environment, especially sea water and it has not in accordance with the Balinese people, especially the Palemahan and this study indicate that the waste management process at the Jumpai Beach has not fully implemented the Laws and Regulations concerning waste management.
The Potential of Agroforestry to Overcome Agricultural Land Degradation in the Dieng Plateau, Central Java, Indonesia
Authors: Pujiwinarko Ari , Soeprobowati Tri Retnaningsih , Kismartini Kismartini
Published: November 2023

Most of the Dieng Plateau area in Central Java, Indonesia, is a stretch of agricultural land in the upper watershed whose sustainability is threatened. The degradation of agricultural land, which affects the surrounding area and the area beneath it, is an old problem that still needs to be resolved. Agroforestry has been promoted as a sustainable land management system with various benefits and advantages. However, data and information regarding its potential to overcome the degradation of agricultural land in the highlands still need to be provided. Our integrative review found that the benefits and advantages of agroforestry to reduce erosion rates and increase land fertility have the most potential to overcome the various impacts of agricultural land degradation in the Dieng Plateau. Adopting agroforestry deserves to be one of the main strategies to overcome the degradation of agricultural land in the highlands, not only in the Dieng Plateau but also in other highlands worldwide.
Mapping the Scientific Literature on Mangrove Conservation in Indonesia: A Bibliometric Analysis to Environmental Research
Authors: Husna Jazimatul , Wijayanti Ima , Budiastusi Wiratmo Liliek , Indrahti Sri , Naryoso Agus , Edzan Che Nasir Nor , Patria Ratna Maharani , Mulyaning Andini Berliana , Raihan Putra Ratarno Dhaka
Published: November 2023

In 2022, the Global Mangrove Alliance (GMA) released the latest map of the world's mangroves. Southeast Asia is home to the most extensive mangrove forests, with Indonesia contributing one-fifth of the world's total mangrove area. Given this, government policies and in-depth studies are needed. The purpose of this study is to contribute to and complement the studies conducted by previous researchers. This study uses the bibliometric analysis methodology with VOSviewer and the biblioshiny package in RStudio. This study investigates the development of international publications and research on mangroves in Indonesia. The methodology and framework were adapted from the bibliometric analysis procedures developed by Donthu in 2021. The published results and findings on mangroves increased by 475%. There is a scientific collaboration between world scientists and Indonesian scientists, for example, the collaboration of Kauffman J.B. Alongi D.M., Murdiyarso D., and Basyuni. The book World Atlas of Mangroves, written by M. Spalding et al., and the book Mangrove Guidebook for Southeast Asia, written by Giesen et al., have received many citations and have become essential references for many world mangrove researchers. Many Scopus journals that have a high h-Index and ranking (Q) have published publications on mangrove ecosystems in Indonesia, for example, Biodiversity (Q2), AACL Bioflux (Q2), and Ocean and Coastal Management (Q1). Many keywords related to various aspects of the mangrove ecosystem were found: conservation, biodiversity, blue carbon, ecotourism, climate change, remote monitoring, avicennia marina, rhizophora, and seagrass.
Forecasting Agricultural Seeds Sales System Using The Additive Holt-Winters Method
Authors: A’yuni Ar Ruhimat Qurrota , Surya Lestari Ika , Bukhori Saiful
Published: November 2023

Buana Seed is an agricultural business sector that sells various kinds of agricultural seeds, such as: chilli seeds, Servo tomato seeds, and Ranti tomato seeds. The problem found was the sale of seeds that was not optimal, because the owner used the previous period's sales as a reference. Due to an error in determining the number of seeds to be sown, there is often an overstock or understock. An information system is needed to assist seeders in determining the number of seeds to be sown. The forecasting method used is the "Additive Holt-Winters" method where the data used is sales data for each seed from January 2019 to August 2021. This method is based on three elements, namely linear, trend and seasonal data elements by giving three weights respectively in their predictions, namely α, β, and γ. There were 10 combinations of alpha (α), beta (β), and gamma (γ) made in the calculation. The accuracy value will be calculated using MAPE. MAPE results from each combination are different. The results of this forecasting calculation will be a reference in determining the seeds to be sown so that sales become optimal.
Implementation of the Green Open Space Provision in DKI Jakarta
Authors: Mbarep Daniel Putra Pardamean , Kampono Irfan , Sutansyah Deni , Sutisna Deny , Nurdiansah Doni
Published: November 2023

The percentage of land for green open space in DKI Jakarta in 2013 did not meet the minimum criteria because there were 12.12% with existing vegetation of 4.73% and non-vegetation of 7.38%, so improvements are needed. This study was conducted to re-examine the implementation of the green open space provision by looking at the percentage of land for green open space in DKI Jakarta in the last 5 years (2017 and 2021). ArcMap 10.8 software is used to interpret data from LANDSAT 8 with BAND 4 and 5, then calculated with the Normalized Difference Vegetation Index (NDVI) to determine the percentage of land for green open space in DKI Jakarta. The results showed that the percentage of land for green open space in DKI Jakarta in 2017 was 12.10%, with existing vegetation of 4.33% and non-vegetation of 7.77%. The percentage of land for green open space in DKI Jakarta in 2021 was 12.11%, with existing vegetation 3.59% and non-vegetation 8.52%. This information shows that the implementation of the green open space provision in DKI Jakarta still does not meet the minimum criteria that exist in appropriate research and policies.
Supporting Capacity of Tugurejo Tread Mangrove Ecotourism
Authors: Mirza Mohamad , Anggoro Sutrisno , Muhammad Fuad
Published: November 2023

The mangrove forest on the coast of Tapak Tugurejo is one of the best mangrove forests in the city of Semarang which is inhabited by various species and has a high density. This mangrove forest is the main potential of coastal ecotourism in Tapak. This study aims to determine the carrying capacity of Mangrove Ecotourism on the coast of the Tugurejo Tread, Semarang. The method used is to assess the carrying capacity. The carrying capacity of Mangrove Tread Ecotourism is 668 people per day. This value is greater than the actual value of the number of tourists 136 people per day. Thus, the number of tourists who are expected to be able to travel in the Tugurejo Mangrove without causing disturbance to the ecosystem of the conservation area is a maximum of 668 people per day. Because the maximum number of visits in the Tugurejo Mangrove ecotourism area is 136 visitors.
Development of a small-scale hybrid solar-wind power system for supporting tourism program at Sepanjang beach, Indonesia
Authors: Sudarsono  , Rusianto Toto , Kristiyana Samuel
Published: November 2023

Although many solar power plant as well as wind power plant have been developed and built, but none of those plants are built in a small- scale bybrid system for supporting tourism program so far. Thus, the present work aims to develop and build a small scale solar-wind hybrid power plant for tourism program at Sepanjang beach, Yogyakarta, Indonesia. The small- scale hybrid solar-wind power system is developed and installed successfully at Sepanjang beach Yogyakarta Indonesia. It can be concluded that the system able to generated electric power to which is used for electrification at the site. The system help to promote the tourism program at Sepanjang beach. From the performance test, it can be concluded that the wind turbine and the solar efficiency are 46.89% and 48.10%, respectively. Meanwhile, the overall efficiency of the system is about 22.50%.
The Policy to Increase the Price of Fuel Oil (BBM) in 2022 Becomes a Momentum in Encouraging the Use of Electric Vehicles in Indonesia
Authors: Fibrin Metana Filia , Sudarmo  , Dwi Wahyunengseh Rutiana
Published: November 2023

The policy to increase the price of fuel oil (BBM) in 2022 is due to world crude oil prices. This will certainly have an impact on the swelling of the fuel subsidy budget allocation to the public which originates from the state budget. but an increase in fuel prices can encourage people to switch to using vehicles with electrical energy sources because they are environmentally friendly and sustainable. This is an innovation in reducing the dominance of the use of fuel which contributes to various types of gases that are harmful to the environment.
Analyzing Hydrogen Gas Production from Seawater Using the Electrolysis Method with the Addition of Acetic Acid and Sulfuric Acid Catalysts
Authors: Wahyono Yoyon , Hadiyanto Hadiyanto , Ahmad Baihaqi Rifqi , Indrawan Wisnu
Published: November 2023

Based on proven reserves, Indonesia's natural gas is roughly 34 years old. Consequently, it is necessary to develop new renewable gas-based energy. This study offers an alternative, sustainable energy option in the form of the creation of hydrogen gas. Electrolysis of saltwater results in the creation of hydrogen gas. In this research, the constant variables are the raw materials, the electrolysis period of 5 minutes, and the voltage of 6 volts. 2000 ml seawater electrolysis, variation of addition of acetic acid catalyst, and variation of addition of sulfuric acid catalyst are not fixed variables in this study. The electrolysis of 0.8 L seawater and 1.2 L sulfuric acid yielded the best mass, volume, and concentration of hydrogen gas: 1.37 x 10-3 g, 1.37 x 10-2 L, and 4500 ppm. The Scanning Electron Microscope (SEM) analysis revealed that the salt's particle size was 25 µm. The Energy Dispersive X-Ray Spectroscopy (EDS) examination revealed that Magnesium Oxide (MgO) comprised 35.76 wt% of the biggest salt composition. Periodically, electrodes must be changed because they get oxidized.
Association Between PM2,5 Wood Dust Exposure and Acute Respiratory Infection on Plywood Industry Workers in PT. Muara Kayu Sengon, Jatilawang District, Banyumas Regency
Authors: Ro’in Firda , Raharjo Mursid , Setiani Onny
Published: November 2023

The plywood processing industry is one of the fastest growing industries. However, this has a negative impact and may cause the emergence of air pollution by dust produced from the plywood processing industry. Air pollution caused by the plywood processing industry can trigger problems such as the atmosphere, the economy, and health. The plywood processing industry has potential to create a source of pollution in the form of dust which is harmful to the environment and the health of workers. This study aimed to determine and analyze the assosiation between PM2,5 wood dust exposure and the case of acute respiratory infection (ARI) in plywood industry workers. The research method used is cross-sectional with a total sample of 142 female workers at 17 locations PM2,5 wood dust measurement and using a standardized
Questionnaire British Medical Research Council (QUES BMRC -86). PM2,5 wood dust measurement using tools DustTrak. Based on the results of the study showed that the average of PM2,5 at 17 points of 5.23 mg/m3 which exceeds the Threshold Value according to the Regulation of the Minister of Manpower of the Republic of Indonesia Number 5 of 2018 concerning the Threshold Value of Chemical Factors in the Air of the Work Environment for Types of Softwood Dust, namely 5 mg/m3 who are at risk of experiencing the case of acute respiratory infection. The results of the analysis and the results of the logistic regression test show that there are 4 significant variables is a assosiation between with the case of acute respiratory infection, for exposure to PM2,5 dust (p = <0.001; RP = 12,757; 95% CI = 1,819 - 89,477), working period (p value = <0.001; RP = 13.048; 95% CI = 4.217 – 40.377), use of personal protective equipment (p value = <0.001; IDR 7,568; 95% CI = 2.453 – 23.352), and age (p value = <0.001, RP = 5.582, 95% CI = 2.323 – 13.413). The conclusion of this study is that there is a assosiation between exposure to PM2,5, wood dust, years of service, use of personal protective equipment, age and the case of acute respiratory infection in plywood industry workers. Therefore, to prevent the occurrence of acute respiratory infection, workers are advised to use complete personal protective equipment when doing work in the plywood industry of PT. Muara Kayu Sengon, Jatilawang District, Banyumas Regency.
An Assesment of Adherence Treatment and Determinants among Hypertensive Patients Attending Primary Health Care in Medan City
Authors: Siregar Fazidah A. , Asfriyati  , Makmur Tri
Published: November 2023

Hypertension is a serious health problem that causes morbidity. Prevalence of hypertension in Medan City was 22.53% and only 9,95% of them with controlled hypertension. Patients’ adherence to treatment is a key factor in controlling hypertension and its complications. The objective of this study was to assess the adherence to treatment of hypertensive patients and to determine factors that affect their adherence to treatment. This is a cross sectional study and conducted in August–October 2021 at Primary health care in Medan City. A total of one hundred and fifty-three hypertensive patients were involved in this study. Data were collected through interviews using questionnaires. Previously respondents are required to fill out the validated Indonesian version of the MMAS-8 questionnaire after signing informed consent. Data were analyzed using Simple and Multiple Logistic Regression. The results showed that 52.3% of the respondents had high level of adherence, and 47,7% respondents had low level of adherence. The multiple logistic regression revealed that family history with hypertension, the side effect of treatment, knowledge about the disease, and family support were contributing factors to adherence to treatment among hypertensive patients. It was suggested health care providers pay attention to educating patients on hypertension adherence treatment.
Beobachtung, Bauchgefühl & Beharrlichkeit – Intuition im Clinical-Reasoning-Prozess
Authors: Stehrenberger Andrea , Pfeiffer Fabian
Published: November 2023

Clinical Reasoning ist ein analytischer Denkprozess. Für Intuition bleibt im ersten Moment wenig Raum. Wie wichtig genaues Beobachten, Bauchgefühl und Beharrlichkeit sein können, zeigt ein komplexer Fall von Rückenschmerzen. Andrea Stehrenberger schildert ihre detaillierte Diagnostik, das kritische Hinterfragen eigener Hypothesen und das Vertrauen auf ihre Intuition. Erst durch Beharrlichkeit entpuppt sich ein LWS-Problem als ernsthafte Erkrankung.
Mykid nach Tinea manus bullosa durch Trichophyton mentagrophytes
Authors: Schießl Jasmin , Richter Margit , Syhre Ellen , Klonowski Esther , Krüger Constanze , Uhrlaß Silke , Nenoff Pietro
Published: November 2023

Id-Reaktionen im Rahmen von Infektionen der Haut durch Erreger von Dermatomykosen sind
hierzulande wahrscheinlich weit unterdiagnostiziert. Bei einem 10-jährigen Mädchen kam es nach
dem Kontakt mit einer Katze zu einer Tinea manus bullosa. Als Erreger wurde Trichophyton mentagrophytes identifiziert und mittels Sequenzierung als
zoophiler Genotyp III* bestätigt. Behandelt wurde rein topisch mit Miconazol +
Flupredniden-Creme. In den nächsten Tagen entwickelten sich volar an beiden Handgelenken und
an den Beugeseiten der Unterarme pruriginöse Papeln und Vesiculae im Sinne eines Mykids oder
Id-Reaktion als Folge der Dermatophytose. Behandelt wurde kurzzeitig mit topischen
Glukokortikoiden, das Exanthem bildete sich schnell zurück. Die Tinea manus heilte zeitgleich
und ebenfalls folgenlos ab.
Influence of Serum Ferritin and B12 Levels in the Functional Outcomes of Patients with Ruptured and Unruptured Intracranial Aneurysms
Authors: Rabelo Nícollas Nunes , Coelho Antônio Carlos Samaia da Silva , Pipek Leonardo Zumerkorn , Telles Joao Paulo Mota , Barbato Natalia Camargo , Yoshikawa Marcia Harumy , Barbosa Guilherme Bitencourt , Teixeira Manoel Jacobsen , Figueiredo Eberval Gadelha
Published: November 2023

Introduction Pathological processes in the arterial wall that result in vessel dilation are the cause of intracranial aneurysms (IAs), and the risk factors for their formation and progression are not well established. Ferritin is associated with inflammation and angiogenesis; it has protective antioxidative activity, and controls cell differentiation. Vitamin B12 is related to neurological and hematological disorders; it can be used as differential diagnosis tool, and acts in the control of homocysteinemia, a predictor of worse prognosis. The present article aims to assess the correlation between serum ferritin and B12 levels and the patient's functional outcome.

Materials and Methods In the present cohort study, we assessed the serum levels of ferritin and B12, as well as the scores on the modified Rankin and Glasgow Outcome Scales at 6 months, of 2 groups, one with 19 and the other with 49 individuals, out of 401 patients treated for IA at Universidade de São Paulo from 2018 to 2019. We performed a statistical analysis, using logistic regression, to determine the aforementioned correlation.

Results In the univariable analysis, the serum levels of ferritin showed no significant impact on the functional outcome (odds ratio [OR]: 0.96 for every 100 pg/mL increase; 95% confidence interval [95%CI]: 0.761–1.210; p = 0.732); neither did the serum levels of B12 (OR: 0.998 for every 100 pg/mL increase; 95%CI: 0.826–1.206; p = 0.987). Moreover, no significant impact on the functional outcome was observed in the multivariable analysis regarding the serum levels of B12, age, hypertension, and aneurysm rupture (OR: 1.086 for every 100 pg/mL increase; 95%CI: 0.847–1.392; p = 0.513).

Conclusion We were not able to confirm a statistical correlation regarding the serum levels of ferritin and B12, and functional outcome of IA patients. These variables might be linked to other determinants of the pathophysiology of IAs, like inflammation and homocysteinemia.
Computational study on structural, elastic, mechanical and optical properties of K2AgAs ternary semiconductor compound
Authors: Musembi Robinson , Mbilo Mwende
Published: November 2023

In this study, the structural, electronic, elastic, mechanical, and optical properties of a new Zintl phase K2AgAs ternary semiconductor compound have been investigated by the first-principles method using the plane-wave self-consistence field method. A triangulation of different exchange-correlation functionals, including local density approximation-LDA-PZ, generalized gradient approximation (GGA)-Q2D, GGA-BLYP, GGA-Perdew–Burke–Ernzerhof (PBE), GGA-PBESol, and GGA-revPBE, have been utilized to predict the properties of the material. The computed structural properties predicted that the K2AgAs compound is thermodynamically stable, and the lattice parameters are consistent with the reported experimental values. The electronic properties show that the bandgap ranges between 0.6645 and 1.1915 eV, while the conduction and valence bands are formed mainly through the hybridization of the As-2p, Ag-2p and Ag-3d, As-2p states, respectively, with other states making minimal contribution. From the calculation of elastic properties, K2AgAs were predicted to be mechanically stable. Notably, K2AgAs has been predicted to absorb light within the ultraviolet-visible regime. Owing to their good thermodynamic and mechanical stability, wide coverage of absorption in the UV-Vis region of the solar spectrum, and narrow bandgaps, K2AgAs can be formed/synthesized and applied as the active photoactive material in solar cells and other photovoltaics.
The dynamics of fractional KdV type equations occurring in magneto-acoustic waves through non-singular kernel derivatives
Authors: AlBaidani Mashael M. , Ganie Abdul Hamid , Khan Adnan
Published: November 2023

To study magneto-acoustic waves in plasma, we will use a numerical method based on the Natural Transform Decomposition Method (NTDM) to find the approximative solutions of nonlinear fifth-order KdV equations. The method combines the familiar Natural transform (NT) with the standard Adomian decomposition method. The fractional derivatives considered are the Caputo–Fabrizio and the Atangana–Baleanu derivatives in the sense of Caputo derivatives. Adomian polynomials may be employed to tackle nonlinear terms. In this method, the solution is calculated as a convergent series, and it is demonstrated that the NTDM solutions converge to the exact solutions. A range of two- and three-dimensional figures have been used to illustrate the dynamic behavior of the derived solutions. The tables provide a visual representation of numerical data. The physical behavior of the derived solutions about fractional order is further demonstrated by several simulations. When addressing nonlinear wave equations in science and engineering, the NTDM offers a broad range of applications. Several examples are given to highlight the importance of this work and to demonstrate the simplicity and trustworthiness of the method.
Polypyrrole nanoparticles loaded with doxorubicin for pH-responsive combinational photothermal-chemotherapy of cancer cells
Authors: Liu Jinhua , Zhu Guoren , Liu Yuanan , Wang Xiaohui
Published: November 2023

The combined treatment method integrated photothermal therapy (PTT) with chemotherapy is extremely promising owing to the synergistic therapeutic effect as compared to single PTT or chemotherapy. To facilitate more novel and facile photothermal-chemotherapy drugs as well as promote controllable combination therapy, we have developed a mild and facile method to fabricate polymer polypyrrole (PPy)-doxorubicin (DOX) nanoparticles (NPs) as pH-responsive drug nanocarriers for synergistic photothermal-chemotherapy. In the nanoplatform, poly-L-lysine (PLL)-modified PPy serves as the photothermal material, and (DOX) molecules are adopted as the chemotherapy agent. Based on the cross-linking reaction of glutaraldehyde, DOX molecules are flexibly and efficiently assembled on the surface of PLL-modified PPy NPs. The obtained PPy-DOX NPs possess high photothermal effect, superior loading capacity of DOX, and controlled drug release behavior. The combination photothermal-chemotherapy based on PPy-DOX NPs has significantly enhanced the antitumor therapy effect. In general, the designed PPy-DOX NPs may be a potential drug delivery nanoplatform for cancer combination therapy.
Industrial-era decline in Arctic methanesulfonic acid is offset by increased biogenic sulfate aerosol
Authors: Jongebloed Ursula A. , Schauer Andrew J. , Cole-Dai Jihong , Larrick Carleigh G. , Porter William C. , Tashmim Linia , Zhai Shuting , Salimi Sara , Edouard Shana R. , Geng Lei , Alexander Becky
Published: November 2023

Marine phytoplankton are primary producers in ocean ecosystems and emit dimethyl sulfide (DMS) into the atmosphere. DMS emissions are the largest biological source of atmospheric sulfur and are one of the largest uncertainties in global climate modeling. DMS is oxidized to methanesulfonic acid (MSA), sulfur dioxide, and hydroperoxymethyl thioformate, all of which can be oxidized to sulfate. Ice core records of MSA are used to investigate past DMS emissions but rely on the implicit assumption that the relative yield of oxidation products from DMS remains constant. However, this assumption is uncertain because there are no long-term records that compare MSA to other DMS oxidation products. Here, we share the first long-term record of both MSA and DMS-derived biogenic sulfate concentration in Greenland ice core samples from 1200 to 2006 CE. While MSA declines on average by 0.2 µg S kg
–1
over the industrial era, biogenic sulfate from DMS increases by 0.8 µg S kg
–1
. This increasing biogenic sulfate contradicts previous assertions of declining North Atlantic primary productivity inferred from decreasing MSA concentrations in Greenland ice cores over the industrial era. The changing ratio of MSA to biogenic sulfate suggests that trends in MSA could be caused by time-varying atmospheric chemistry and that MSA concentrations alone should not be used to infer past primary productivity.
Essential roles of the ANKRD31–REC114 interaction in meiotic recombination and mouse spermatogenesis
Authors: Xu Jiaqi , Li Tao , Kim Soonjoung , Boekhout Michiel , Keeney Scott
Published: November 2023

Meiotic DNA double-strand breaks (DSBs) initiate homologous recombination and are crucial for ensuring proper chromosome segregation. In mice, ANKRD31 recently emerged as a regulator of DSB timing, number, and location, with a particularly important role in targeting DSBs to the pseudoautosomal regions (PARs) of sex chromosomes. ANKRD31 interacts with multiple proteins, including the conserved and essential DSB-promoting factor REC114, so it was hypothesized to be a modular scaffold that “anchors” other proteins together and to meiotic chromosomes. To determine whether and why the REC114 interaction is important for ANKRD31 function, we generated mice with
Ankrd31
mutations that either reduced (missense mutation) or eliminated (C-terminal truncation) the ANKRD31–REC114 interaction without diminishing contacts with other known partners. A complete lack of the ANKRD31–REC114 interaction mimicked an
Ankrd31
null, with delayed DSB formation and recombination, defects in DSB repair, and altered DSB locations including failure to target DSBs to the PARs. In contrast, when the ANKRD31–REC114 interaction was substantially but not completely disrupted, spermatocytes again showed delayed DSB formation globally, but recombination and repair were hardly affected and DSB locations were similar to control mice. The missense
Ankrd31
allele showed a dosage effect, wherein combining it with the null or C-terminal truncation allele resulted in intermediate phenotypes for DSB formation, recombination, and DSB locations. Our results show that ANKRD31 function is critically dependent on its interaction with REC114 and that defects in ANKRD31 activity correlate with the severity of the disruption of the interaction.
Creating an information security policyin a bank
Authors: T. Kamou Olivier Mozard
Published: November 2023

Information security policies are particularly important when it comes to maintaining information security within an organization. As a result, creating an information security policy is an invaluable process that cannot be undermined. This study aims at investigating how these information security policies are created, specifically in banks, from a linguistic perspective. The study employed the use of corpora and analyzed ten information security policies of banks randomly collected online. The analyses were categorized under five levels of linguistic analysis which included: the mode, lexis, grammar, speech acts, and discourse. Some statistical analyses which involved clustering were also performed at the level of discourse in order to find similar patterns in the information security policies. The results show that banks use the same linguistic features when writing their information security policies. The results also reveal how these linguistic features are used to develop a comprehensive and effective information security policy.
A cross-sectional study on oral health-care habits and oral-health-related quality-of-life in marginalized persons in Copenhagen
Authors: Boeskov Øzhayat Esben , Elmongy Ashraf , Tanderup Lene , Bordorff Sine Lykke , Thiesen Henrik
Published: November 2023

Objective: The aim of this cross-sectional study was to investigate the oral-health-related quality-of-life (OHRQoL) and oral health-care habits in a population of marginalized persons in Copenhagen.
Materials and Methods: Patients attending a dental clinic for marginalized persons filled in the 14-item version of the oral-health-impact profile (OHIP-14) regarding their OHRQoLand a questionnaire on their oral health-care habits. Age, gender, smoking habits, need for general and oral health-care, and living conditions were further registered.
Results: Of the 212 participants, 72% had not visited a dental clinic within the past two years and in 68% of the cases, the last dental visit was related to dental treatment. Tooth brushing at least once a day was reported by 93%. The mean OHIP-14 score in the participants was 24.9 (SD: 13.6). The most frequent problems were pain, chewing difficulties, being self-conscious, tense, and embarrassed as well as affected life. The mean OHIP-14 score was significantly higher in participants in need of general health-care (29.5, SD: 12.2) than in participants not in need of general health-care (22.8, SD: 13.9). The same applied to participants referred for dental treatment (26.1, SD: 12.7) compared to participants not being referred (20.2, SD: 15.9).
Conclusions: The OHRQoLis poor in the population with pain, chewing difficulties and aesthetic issues as the most prominent problems. The participants had low and treatment-oriented use of the dental care system. This indicates a high need for dental care in the population with a focus on including them in the dental care system.
Effect of cooling rate on solidification points and atomic structures of metal nanoclusters: a molecular dynamics simulation study
Authors: Samantaray Minati P , Sarangi Soumya S
Published: November 2023

In this work, the micro-structural evolution during the solidification process of three metal nanoclusters (copper, nickel, and silver) containing 2048 atoms each, subjected to different cooling rates are investigated. Molecular dynamics (MD) simulations in conjunction with modified embedded atom method (MEAM) potentials have been employed to carry out the work. For different cooling rates, the solidification points of the nanoclusters are estimated from the variation in average potential energy of the systems during the crystallization process, and the structural evolutions are analysed by utilising radial distribution function and common neighbour analysis method. The results advocate that the cooling rate has a profound impact on the structures of the solidified nanoclusters. The critical cooling rate for each nanocluster has been captured, where a glassy/amorphous structure is observed. Polycrystalline nano-structures (consisting of amorphous, FCC and HCP) are observed below these critical cooling rates and the number of close-packed structures (FCC, HCP) are found to decrease with the increase in cooling rate. The findings of this work would be helpful in various practical applications of the metal nanoclusters, where the structure of nanoclusters directly affect.
Optical manipulation of the topological phase in ZrTe5 revealed by time- and angle-resolved photoemission
Authors: Huang 黄 Chaozhi 超之 , Xu 徐 Chengyang 骋洋 , Zhu 朱 Fengfeng 锋锋 , Duan 段 Shaofeng 绍峰 , Liu 刘 Jianzhe 见喆 , Gu 顾 Lingxiao 凌霄 , Wang 王 Shichong 石崇 , Liu 刘 Haoran 浩然 , Qian 钱 Dong 冬 , Luo 罗 Weidong 卫东 , Zhang 张 Wentao 文涛
Published: November 2023

High-resolution time- and angle-resolved photoemission measurements were conducted on the topological insulator ZrTe5. With strong femtosecond photoexcitation, a possible ultrafast phase transition from a weak to a strong topological insulating phase was experimentally realized by recovering the energy gap inversion in a time scale that was shorter than 0.15 ps. This photoinduced transient strong topological phase can last longer than 2 ps at the highest excitation fluence studied, and it cannot be attributed to the photoinduced heating of electrons or modification of the conduction band filling. Additionally, the measured unoccupied electronic states are consistent with the first-principles calculation based on experimental crystal lattice constants, which favor a strong topological insulating phase. These findings provide new insights into the longstanding controversy about the strong and weak topological properties in ZrTe5, and they suggest that many-body effects including electron–electron interactions must be taken into account to understand the equilibrium weak topological insulating phase in ZrTe5.
Resonant interaction between runaway electrons and the toroidal magnetic field ripple in TCV
Authors: Wijkamp T.A. , Hoppe M. , Decker J. , Duval B.P. , Perek A. , Sheikh U. , Classen I.G.J. , Jaspers R.J.E. ,   the TCV team
Published: November 2023

This work explains the anomalously high runaway electron (RE) pitch angles inferred in the flat-top of dedicated Tokamak à Configuration Variable (TCV) experiments. Kinetic modelling shows that the resonant interaction between the gyromotion of the electrons and the toroidal magnetic field ripple will give rise to strong pitch angle scattering in TCV. The resulting increase in synchrotron radiation power losses acts as a RE energy barrier. These observations are tested experimentally by a magnetic field ramp-down, which gradually reduces the resonant parallel momentum at which the REs interact with the ripple. Resulting changes in synchrotron emission geometry and intensity are observed using three multi-spectral camera imaging systems, viewing the RE beam at distinct spatial angles in multiple wavelength ranges. Experimental reconstructions of the RE distribution in momentum- and real-space are consistent with kinetic model predictions.
Capillary efficiency study in leaf vein morphology inspired channels
Authors: Shen Jingyu , Guo Ce , Ma Yaopeng , Dong Ao
Published: November 2023

Inspired by the capillary transport function of plant leaf veins, this study proposes three typical leaf vein features by observing a large number of leaves, including wedge shape, branch asymmetry, as well as hierarchical arrangement, and investigates their capillary transport mechanism. Not only a preliminary theoretical analysis of capillary flow in the bio-inspired channels was carried out, but the COMSOL Multiphysics simulation software was also used to simulate gas–liquid two-phase flow in biomimetic channels. The results reveal the efficient transport mechanism of the leaf vein inspired structure and provide insight into the design of capillary transmission channels.
On the adiabatic approximation for the laser-dressed atom
Authors: Flegel A V , Frolov M V
Published: November 2023

The adiabatic approximation is analyzed for non-perturbative interaction of an atomic system with an intense low-frequency laser field. We find that the well-known adiabatic ansatz, which consists in using the DC-based Green’s and wave functions for an atom in the instantaneous AC field to calculate transition matrix elements, exceeds the level of accuracy of the adiabatic approximation and requires further theoretical revision. It is shown that the non-analyticity in the field strength of the DC-based Green’s and wave functions leads to violation of the adiabaticity constrains and the appearance of rapidly oscillating components in the transition matrix elements. We suggest an improved adiabatic approach utilizing the analytical parts in the DC-based Green’s and wave functions. We illustrate our revised adiabatic approach for analysis of atomic polarizability in two-component laser field with an intense infrared and perturbative extreme ultraviolet components within the zero-range potential model.
Single flow treatment degradation of antibiotics in water using falling-film dielectric barrier discharge
Authors: XU 许 Zhiyuan 志远 , ZHANG 章 Cheng 程 , WU 伍 Yunjian 云健 , HUANG 黄 Bangdou 邦斗 , XI 席 Dengke 登科 , ZHANG 张 Xiaoxing 晓星 , SHAO 邵 Tao 涛
Published: November 2023

The environmental contamination caused by antibiotics is increasingly conspicuous due to their widespread manufacture and misuse. Plasma has been employed in recent years for the remediation of antibiotic pollution in the environment. In this work, a falling-film dielectric barrier discharge was used to degrade the antibiotic tetracycline (TC) in water. The reactor combined the gas-liquid discharge and active gas bubbling to improve the TC degradation performance. The discharge characteristics, chemical species’ concentration, and degradation rates at different parameters were systematically studied. Under the optimized conditions (working gas was pure oxygen, liquid flow rate was 100 mL/min, gas flow rate was 1 L/min, voltage was 20 kV, single treatment), TC was removed beyond 70% in a single flow treatment with an energy efficiency of 145 mg/(kW·h). The reactor design facilitated gas and liquid flow in the plasma area to produce more ozone in bubbles after a single flow under pure oxygen conditions, affording fast TC degradation. Furthermore, long-term stationary experiment indicated that long-lived active species can sustain the degradation of TC. Compared with other plasma treatment systems, this work offers a fast and efficient degradation method, showing significant potential in practical industrial applications.
Early Detection of Depression in Parkinson’s Disease: Psychometrics and Diagnostics of the Spanish Version of the Beck Depression Inventory
Authors: D’Iorio Alfonsina , Maggi Gianpaolo , Guida Pasqualina , Aiello Edoardo Nicolò , Poletti Barbara , Silani Vincenzo , Ticozzi Nicola , Santangelo Gabriella , Obeso Ignacio
Published: November 2023

Objective

Depression is one of the most disabling non-motor symptoms in Parkinson’s disease (PD) and requires proper diagnosis as it negatively impacts patients’ and their relatives quality of life. The present study aimed to examine the psychometric and diagnostic properties of the Beck Depression Inventory-I (BDI-I) in a Spanish PD cohort.

Method

Consecutive PD outpatients completed the Spanish version of the BDI-I and other questionnaires assessing anxiety and apathy. Patients’ caregivers completed the depression/dysphoria domain of the Neuropsychiatric Inventory (NPI-D). The internal consistency, convergent and divergent validity and the factorial structure of BDI-I were evaluated, and an optimal cut-off was defined by means of the Youden index.

Results

The BDI-I proved to have a good internal consistency and was underpinned by a mono-component structure. Regarding construct validity, the BDI-I was substantially related to anxiety and apathy measures in PD. Furthermore, the BDI-I overall showed good accuracy with adequate sensitivity and specificity. The optimal cut-off point was defined at 10.

Conclusions

We provided evidence of the psychometric and diagnostic properties of the Spanish version of the BDI-I as a screening tool for depression in Spanish speaking PD patients, suggesting its usefulness in clinical research and practice.
Fed-batch cultivation of Euglena gracilis for the high-yield production and GPC-assisted molecular weight determination of paramylon
Authors: Fukuda Mizuki , Kinkawa Manato , Hayashi Masahiro
Published: November 2023

Paramylon, a starch-like carbohydrate accumulated in Euglena gracilis cells, could be a potential source as a raw material for chemical products; its high-yield production would thus be highly desired. Although the molecular weight and polymerization degree of paramylon are important properties for its use as a raw material for chemical products, the available information about paramylon molecular weight remains insufficient. Therefore, in this study, we investigated a high-density E. gracilis culture approach and how culture conditions affect paramylon molecular weight. The nitrogen source, cultivation temperature, and nutrient feeding were optimized for maximum biomass and paramylon productivity. The maximum dry cell weight and paramylon content yields reached 108.9 g/L and 87.2%, respectively. Paramylon molecular weight was in the range of 220 000–320 000 Da. Our gel permeation chromatography analysis showed that the cells with a higher paramylon content tended to contain paramylon of a higher molecular weight.
Circulating metabolites associated with kidney function decline and incident CKD: a multi-platform population-based study
Authors: van der Burgh Anna C , Geurts Sven , Ahmad Shahzad , Ikram M Arfan , Chaker Layal , Ferraro Pietro Manuel , Ghanbari Mohsen
Published: November 2023

Background

Investigation of circulating metabolites associated with kidney function and chronic kidney disease (CKD) risk could enhance our understanding of underlying pathways and identify new biomarkers for kidney function.

Methods

We selected participants from the population-based Rotterdam Study with data on circulating metabolites and estimated glomerular filtration rate based on serum creatinine (eGFRcreat) available at the same time point. Data on eGFR based on serum cystatin C (eGFRcys) and urine albumin-to-creatinine ratio (ACR) were also included. CKD was defined as eGFRcreat <60 ml/min per 1.73 m2. Data on circulating metabolites (ntotal = 1381) was obtained from the Nightingale and Metabolon platform. Linear regression, linear mixed, and Cox proportional-hazards regression analyses were conducted to study the associations between metabolites and kidney function. We performed bidirectional two-sample Mendelian randomization analyses to investigate causality of the identified associations.

Results

We included 3337 and 1540 participants with data from Nightingale and Metabolon, respectively. A total of 1381 metabolites (243 from Nightingale and 1138 from Metabolon) were included in the analyses. A large number of metabolites were significantly associated with eGFRcreat, eGFRcys, ACR, and CKD, including 16 metabolites that were associated with all four outcomes. Among these, C-glycosyltryptophan (HR 1.50, 95%CI 1.31;1.71) and X-12026 (HR 1.46, 95%CI 1.26;1.68) were most strongly associated with CKD risk. We revealed sex differences in the associations of 11-ketoetiocholanolone glucuronide and 11-beta-glucuronide with the kidney function assessments. No causal associations between the identified metabolites and kidney function were observed.

Conclusion

Our study indicates that several circulating metabolites are associated with kidney function which are likely to have potential as biomarkers, rather than as molecules involved in the pathophysiology of kidney function decline.
Responses of birds to observers holding popguns: Hunting history influences escape behavior of urban birds
Authors: Yuan Kaiqi , Yang Shuang , Liu Jianping , Liang Wei
Published: November 2023

Human activities affect bird behavior both directly and indirectly. Birds constantly regulate their behavior in response to human disturbance. Gun hunting, a major directional disturbance, puts enormous selection pressure on birds. In China, gun bans have been in place for nearly 30 years, and little hunting using guns occurs in modern cities. However, little attention has been paid to whether a history of hunting still affects the behavioral adaptations of urban birds. In this study, we compared the flight initiation distance (FID) of the Eurasian tree sparrow Passer montanus, Azure-winged magpie Cyanopica cyanus, Common hoopoe Upupa epops and Eurasian magpie Pica pica in the presence of observers with or without popguns. The Eurasian tree sparrow, Azure-winged magpie, and Eurasian magpie effectively recognized the difference between the observers, and perceived the armed observer as a greater threat, exhibiting earlier escape behavior, but this phenomenon was not found in the Common hoopoe. The different expressions in FID of experimental bird species in China cities may be affected by the different levels of recognition of hunting pressure due to different hunting histories.
Combined laparoscopic pyelolithotomy with retrograde intrarenal surgery in a patient with horseshoe kidney anomaly and kidney stone: a case report
Authors: Sancak Eyüp Burak , Tekin Yakup Emre , Saray Bektas
Published: November 2023

Horseshoe kidney is the most prevalent congenital kidney fusion anomaly, affecting 0.25% of the general population and occurring in 1 in 400–1600 births. Approximately 40 percent of patients develop kidney stones due to anomalies. In our case, we aimed to perform combined laparoscopic pyelolithotomy with retrograde intrarenal surgery (RIRS) instead of percutaneous nephrolithotomy (PNL) in a patient with a horseshoe anomaly. This procedure enabled us to detect the location of the mobile stone with RIRS and then successfully extract it with laparoscopic pyelolithotomy. Laparoscopic pyelolithotomy combined with RIRS is a reasonable additional treatment option for complicated stone surgery due to horseshoe kidney anomalies.