bluuebunny/crossref_metadata_2025 huggingface dataset:
Lupus Anticoagulant Detection under the Magnifying Glass
Authors: Molinari Angelo Claudio , Martini Tiziano , Banov Laura , Ierardi Antonella , Leotta Marzia , Strangio Alessandra , Santoro Rita Carlotta
Published: October 2023

Diagnosis of antiphospholipid syndrome (APS) requires the presence of a clinical criterion (thrombosis and/or pregnancy morbidity), combined with persistently circulating antiphospholipid antibodies (aPL). Lupus anticoagulant (LA) is one of the three laboratory parameters (the others being antibodies to either cardiolipin or β2-glycoprotein I) that defines this rare but potentially devastating condition. For the search for aCL and aβ2-GP-I, traditionally measured with immunological solid-phase assays (ELISA), several different assays and detection techniques are currently available, thus making these tests relatively reliable and widespread. On the other hand, LA detection is based on functional coagulation procedures that are characterized by poor standardization, difficulties in interpreting the results, and interference by several drugs commonly used in the clinical settings in which LA search is appropriate. This article aims to review the current state of the art and the challenges that clinicians and laboratories incur in the detection of LA.
Are ChatGPT’s Free-Text Responses on Periprosthetic Joint Infections of the Hip and Knee Reliable and Useful?
Authors: Draschl Alexander , Hauer Georg , Fischerauer Stefan Franz , Kogler Angelika , Leitner Lukas , Andreou Dimosthenis , Leithner Andreas , Sadoghi Patrick
Published: October 2023

Background: This study aimed to evaluate ChatGPT’s performance on questions about periprosthetic joint infections (PJI) of the hip and knee. Methods: Twenty-seven questions from the 2018 International Consensus Meeting on Musculoskeletal Infection were selected for response generation. The free-text responses were evaluated by three orthopedic surgeons using a five-point Likert scale. Inter-rater reliability (IRR) was assessed via Fleiss’ kappa (FK). Results: Overall, near-perfect IRR was found for disagreement on the presence of factual errors (FK: 0.880, 95% CI [0.724, 1.035], p < 0.001) and agreement on information completeness (FK: 0.848, 95% CI [0.699, 0.996], p < 0.001). Substantial IRR was observed for disagreement on misleading information (FK: 0.743, 95% CI [0.601, 0.886], p < 0.001) and agreement on suitability for patients (FK: 0.627, 95% CI [0.478, 0.776], p < 0.001). Moderate IRR was observed for agreement on “up-to-dateness” (FK: 0.584, 95% CI [0.434, 0.734], p < 0.001) and suitability for orthopedic surgeons (FK: 0.505, 95% CI [0.383, 0.628], p < 0.001). Question- and subtopic-specific analysis revealed diverse IRR levels ranging from near-perfect to poor. Conclusions: ChatGPT’s free-text responses to complex orthopedic questions were predominantly reliable and useful for orthopedic surgeons and patients. Given variations in performance by question and subtopic, consulting additional sources and exercising careful interpretation should be emphasized for reliable medical decision-making.
Targeted Therapy in Rheumatoid-Arthritis-Related Interstitial Lung Disease
Authors: Harrington Robert , Harkins Patricia , Conway Richard
Published: October 2023

Rheumatoid arthritis (RA) is a chronic autoimmune multisystem inflammatory disease in which lung involvement is the most common extra-articular manifestation. Parenchymal lung involvement or interstitial lung disease (ILD) is a significant cause of morbidity and mortality and there is a paucity of evidence-based guidance on how to best treat RA-ILD. This review article aims to evaluate the evidence from cohort studies and best real word data from registries. Extensive discussion of the relative merits and drawbacks of glucocorticoids, various biologics, small molecules and anti-fibrotics is presented. The limited available guidelines in RA-ILD are also discussed and a rational treatment algorithm is offered.
Intra-Cardiac versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion with a Watchman FLX Device
Authors: Pastormerlo Luigi Emilio , Tondo Claudio , Fassini Gaetano , Nicosia Antonino , Ronco Federico , Contarini Marco , Giacchi Giuseppe , Grasso Carmelo , Casu Gavino , Romeo Maria Rita , Mazzone Patrizio , Limite Luca , Caramanno Giuseppe , Geraci Salvatore , Pagnotta Paolo , Chiarito Mauro , Tamburino Corrado , Berti Sergio
Published: October 2023

This study aimed to compare the peri-procedural success and complication rate within a large registry of intra-cardiac echocardiography (ICE)- vs. transesophageal echocardiography (TEE)-guided left atrial appendage occlusion (LAAO) procedures with a Watchmann FLX device. Data from 772 LAAO procedures, performed at 26 Italian centers, were reviewed. Technical success was considered as the final implant of a Watchmann FLX device in LAA; the absence of pericardial tamponade, peri-procedural stroke and/or systemic embolism, major bleeding and device embolization during the procedure was defined as a procedural success. One-year stroke and major bleeding rates were evaluated as outcome. ICE-guided LAA occlusion was performed in 149 patients, while TEE was used in 623 patients. Baseline characteristics were similar between the ICE and TEE groups. The technical success was 100% in both groups. Procedural success was also extremely high (98.5%), and was comparable between ICE (98.7%) and TEE (98.5%). ICE was associated with a slightly longer procedural time (73 ± 31 vs. 61.9 ± 36 min, p = 0.042) and shorter hospital stay (5.3 ± 4 vs. 5.8 ± 6 days, p = 0.028) compared to the TEE group. At one year, stroke and major bleeding rates did not differ between the ICE and TEE groups. A Watchmann FLX device showed high technical and procedural success rate, and ICE guidance does not appear inferior to TEE.
Preoperative Imaging Signs of Cerebral Malperfusion in Acute Type A Aortic Dissection: Influence on Outcomes and Prognostic Implications—A 20-Year Experience
Authors: Al-Tawil Mohammed , Salem Mohamed , Friedrich Christine , Diraz Shirin , Broll Alexandra , Rezahie Najma , Schoettler Jan , de Silva Nora , Puehler Thomas , Cremer Jochen , Haneya Assad
Published: October 2023

Background: Acute type A aortic dissection (ATAAD) continues to be a subject of active research due to its high mortality rates and associated complications. Cerebral malperfusion in ATAAD can have a devastating impact on patients’ neurological function and overall quality of life. We aimed to explore the risk profile and prognosis in ATAAD patients presenting with preoperative imaging signs of cerebral malperfusion (PSCM). Methods: We obtained patient data from our Aortic Dissection Registry, which included 480 consecutive ATAAD cases who underwent surgical repair between 2001 and 2021. Primary endpoint outcomes included the in-hospital and 30-day mortality, postoperative new neurological deficit, mechanical ventilation hours, and intensive care unit (ICU) length of stay. Results: Of the total cohort, 82 patients (17.1%) had PSCM. Both groups had similar distributions in terms of age, sex, and body mass index. The patients in the PSCM group presented with a higher logistic EuroSCORE (47, IQR [31, 64] vs. 24, IQR [15, 39]; p < 0.001) and a higher portion of patients with a previous cardiac surgery (7.3% vs. 2.0%; p = 0.020). Intraoperatively, the bypass, cardioplegia, and aortic cross-clamp times were similar between both groups. However, the patients in the PSCM group received significantly more intraoperative packed red blood cells, fresh frozen plasma, and platelets transfusions (p < 0.05). Following the surgery, the patients who presented with PSCM had markedly longer ventilation hours (108.5 h, IQR [44, 277] vs. 43 h, IQR [16, 158], p < 0.001) and a significantly longer ICU length of stay (7 days, IQR [4, 13] vs. 5 days, IQR [2, 11]; p = 0.013). Additionally, the patients with PSCM had significantly higher rates of postoperative new neurological deficits (35.4% vs. 19.4%; p = 0.002). In the Cox regression analysis, PSCM was associated with significantly poorer long-term survival (hazard ratio (HR) 1.75, 95%CI [1.20–2.53], p = 0.003). Surprisingly, hypertension was shown as a protective factor against long-term mortality (HR: 0.59, 95%CI [0.43–0.82], p = 0.001). Conclusion: PSCM in ATAAD patients is linked to worse postoperative outcomes and poorer long-term survival, emphasizing the need for early recognition and tailored management.
Identifying Trauma Patients in Need for Emergency Surgery in the Prehospital Setting: The Prehospital Prediction of In-Hospital Emergency Treatment (PROPHET) Study
Authors: Isgrò Stefano , Giani Marco , Antolini Laura , Giudici Riccardo , Valsecchi Maria Grazia , Bellani Giacomo , Chiara Osvaldo , Bassi Gabriele , Latronico Nicola , Cabrini Luca , Fumagalli Roberto , Chieregato Arturo , Sammartano Fabrizio , Sechi Giuseppe , Zoli Alberto , Pagliosa Andrea , Palo Alessandra , Valoti Oliviero , Carlucci Michele , Benini Annalisa , Foti Giuseppe
Published: October 2023

Prehospital field triage often fails to accurately identify the need for emergent surgical or non-surgical procedures, resulting in inefficient resource utilization and increased costs. This study aimed to analyze prehospital factors associated with the need for emergent procedures (such as surgery or interventional angiography) within 6 h of hospital admission. Additionally, our goal was to develop a prehospital triage tool capable of estimating the likelihood of requiring an emergent procedure following hospital admission. We conducted a retrospective observational study, analyzing both prehospital and in-hospital data obtained from the Lombardy Trauma Registry. We conducted a multivariable logistic regression analysis to identify independent predictors of emergency procedures within the first 6 h from admission. Subsequently, we developed and internally validated a triage score composed of factors associated with the probability of requiring an emergency procedure. The study included a total of 3985 patients, among whom 295 (7.4%) required an emergent procedure within 6 h. Age, penetrating injury, downfall, cardiac arrest, poor neurological status, endotracheal intubation, systolic pressure, diastolic pressure, shock index, respiratory rate and tachycardia were identified as predictors of requiring an emergency procedure. A triage score generated from these predictors showed a good predictive power (AUC of the ROC curve: 0.81) to identify patients requiring an emergent surgical or non-surgical procedure within 6 h from hospital admission. The proposed triage score might contribute to predicting the need for immediate resource availability in trauma patients.
Extracorporeal Membrane Oxygenation for Septic Shock in Adults and Children: A Narrative Review
Authors: Broman Lars Mikael , Dubrovskaja Olga , Balik Martin
Published: October 2023

Refractory septic shock is associated with a high risk of death. Circulatory support in the form of veno-arterial extracorporeal membrane oxygenation (VA ECMO) may function as a bridge to recovery, allowing for the treatment of the source of the sepsis. Whilst VA ECMO has been accepted as the means of hemodynamic support for children, in adults, single center observational studies show survival rates of only 70–90% for hypodynamic septic shock. The use of VA ECMO for circulatory support in hyperdynamic septic shock with preserved cardiac output or when applied late during cardio-pulmonary resuscitation is not recommended. With unresolving septic shock and a loss of ventriculo–arterial coupling, stress cardiomyopathy often develops. If the cardiac index (CI) approaches subnormal levels (CI < 2.5 L/min m−2) that do not match low systemic vascular resistance with a resulting loss of vital systemic perfusion pressure, VA ECMO support should be considered. A further decrease to the level of cardiogenic shock (CI < 1.8 L/min m−2) should be regarded as an indication for VA ECMO insertion. For patients who maintain a normal-to-high CI as part of their refractory vasoparalysis, VA ECMO support is justified in children and possibly in patients with a low body mass index. Extracorporeal support for septic shock should be limited to high-volume ECMO centers.
Microbiological and Clinical Assessments of Suture Materials and Cyanoacrylate Application in Impacted Third Molar Surgeries: A Scoping Review
Authors: Scribante Andrea , Ghizzoni Martina , Pellegrini Matteo , Poli Pier Paolo , Maiorana Carlo , Spadari Francesco
Published: October 2023

The extraction of impacted third molars is a common but potentially complication-prone oral surgical procedure. Wound healing plays a vital role in preventing complications. This scoping review aimed to assess the clinical and microbiological aspects of various suture materials and cyanoacrylates. Unlike existing studies, we included more articles and comprehensively compared suture materials. Articles published in languages other than English; duplicate studies; studies deemed irrelevant for the specific research questions, including those analyzing different supplementary treatments or not corresponding to the abstract’s content; ex vivo or experimental animal studies; studies lacking approval from an ethics committee; and narrative reviews, systematic reviews, or systematic and meta-analysis reviews were excluded. Thus, only 17 studies, published between 2000 and 2023, were included in the search. Suture techniques varied among surgeons, with debates on primary and secondary closure methods. A comparison of different suture materials and their effects on wound healing, infection rates, and other factors was described. Cyanoacrylate has also been used as an alternative to traditional sutures. Microbiological analysis showed varying bacterial adhesion based on the suture material, with silk sutures retaining more microbes than PTFE sutures. Clinical assessments have revealed differing inflammatory responses that affect wound healing and complications. Cyanoacrylate has emerged as a promising alternative to traditional sutures, owing to its rapid polymerization and early healing. However, the choice of suture material in impacted third molar surgery remains controversial, considering microbiological factors and clinical outcomes. More extensive randomized clinical trials are required to better understand the effect of suture materials on surgical outcomes and potential improvements. This study could enhance the safety and effectiveness of this common oral surgical procedure.
Advancing Dentistry through Bioprinting: Personalization of Oral Tissues
Authors: Shopova Dobromira , Mihaylova Anna , Yaneva Antoniya , Bakova Desislava
Published: October 2023

Despite significant advancements in dental tissue restoration and the use of prostheses for addressing tooth loss, the prevailing clinical approaches remain somewhat inadequate for replicating native dental tissue characteristics. The emergence of three-dimensional (3D) bioprinting offers a promising innovation within the fields of regenerative medicine and tissue engineering. This technology offers notable precision and efficiency, thereby introducing a fresh avenue for tissue regeneration. Unlike the traditional framework encompassing scaffolds, cells, and signaling factors, 3D bioprinting constitutes a contemporary addition to the arsenal of tissue engineering tools. The ongoing shift from conventional dentistry to a more personalized paradigm, principally under the guidance of bioprinting, is poised to exert a significant influence in the foreseeable future. This systematic review undertakes the task of aggregating and analyzing insights related to the application of bioprinting in the context of regenerative dentistry. Adhering to PRISMA guidelines, an exhaustive literature survey spanning the years 2019 to 2023 was performed across prominent databases including PubMed, Scopus, Google Scholar, and ScienceDirect. The landscape of regenerative dentistry has ushered in novel prospects for dentoalveolar treatments and personalized interventions. This review expounds on contemporary accomplishments and avenues for the regeneration of pulp—dentin, bone, periodontal tissues, and gingival tissues. The progressive strides achieved in the realm of bioprinting hold the potential to not only enhance the quality of life but also to catalyze transformative shifts within the domains of medical and dental practices.
The Preparation and Clinical Efficacy of Amnion-Derived Membranes: A Review
Authors: Ingraldi Alison L. , Audet Robert G. , Tabor Aaron J.
Published: October 2023

Biological tissues from various anatomical sources have been utilized for tissue transplantation and have developed into an important source of extracellular scaffolding material for regenerative medicine applications. Tissue scaffolds ideally integrate with host tissue and provide a homeostatic environment for cellular infiltration, growth, differentiation, and tissue resolution. The human amniotic membrane is considered an important source of scaffolding material due to its 3D structural architecture and function and as a source of growth factors and cytokines. This tissue source has been widely studied and used in various areas of tissue repair including intraoral reconstruction, corneal repair, tendon repair, microvascular reconstruction, nerve procedures, burns, and chronic wound treatment. The production of amniotic membrane allografts has not been standardized, resulting in a wide array of amniotic membrane products, including single, dual, and tri-layered products, such as amnion, chorion, amnion–chorion, amnion–amnion, and amnion–chorion–amnion allografts. Since these allografts are not processed using the same methods, they do not necessarily produce the same clinical responses. The aim of this review is to highlight the properties of different human allograft membranes, present the different processing and preservation methods, and discuss their use in tissue engineering and regenerative applications.
Experimental Parameters Influencing the Cavitation Noise of an Oscillating NACA0015 Hydrofoil
Authors: Föhring Leonie S. , Juhl Peter Møller , Wittekind Dietrich
Published: October 2023

The strong increase in anthropogenic underwater noise has caused a growing intention to design quieter ships given that ship propellers are one of the dominating noise sources along the worldwide shipping routes. This creates an imminent demand for deeper knowledge on the noise generation mechanisms of propeller cavitation. A cavitating, oscillating two-dimensional NACA0015 hydrofoil is analyzed with hydrophone and high-speed video recording as a simplified and manipulatable representative of a propeller blade in a ship’s wake field for the identification of major influencing parameters on the radiated noise. A pneumatic drive allows the application of asymmetrical temporal courses of the angle of attack, a novel amendment to the widely reported sinusoidal setups. Three different courses are tested with various cavitation numbers. The combination of a moderate angle increase and a rapid decrease is found to generate significantly higher pressure peaks compared to symmetrical angular courses. Considering that the rapid change of the angle of attack caused by the inhomogeneous wake field behind the hull is the core of the cavitation occurrence, the understanding of its influence may contribute to the design of quieter ships in the future while still allowing for the necessary high propeller efficiency.
FinTech Adoption of Financial Services Industry: Exploring the Impact of Creative and Innovative Leadership
Authors: Baba Muzamil Ahmad , Haq Zia ul , Dawood Mohsina , Aashish Kumar
Published: October 2023

This paper examines the link between creative and innovative leadership and FinTech adoption through the transmission mechanisms of perceived ease of use (PEOU) and perceived usefulness (PU). This study used a questionnaire survey method to collect data from a sample of 721 employees working in the Indian financial services sector. The data were analyzed using structural equation modelling. The study results revealed a significant and positive influence of creative and innovative leadership, PEOU, and PU on FinTech adoption. Moreover, PEOU and PU mediated the link between creative and innovative leadership and FinTech adoption. This study proposes a new vision for managerial procedures to understand the critical aspects regarding FinTech adoption. The study advises that engineering managers should offer simple and user-friendly technology to enhance the adoption rate. Additionally, the results suggest the importance of creative and innovative leadership for competitively exploiting novel technologies. Given India’s digital revolution and huge market potential, the FinTech sector could prove a game-changer, especially in generating employment for the young and technologically qualified population. Tech-driven organizations could use the study findings strategically in this digital era.
Global Market Perceptions of Cryptocurrency and the Use of Cryptocurrency by Consumers: A Pilot Study
Authors: Murugappan Murugappan , Nair Rashmi , Krishnan Saravanan
Published: October 2023

Cryptocurrencies, like Bitcoin and Ethereum, have garnered global attention in recent years as digital alternatives to traditional fiat currencies. This paper explores the complex landscape of cryptocurrency adoption, consumer behavior, and perceptions. Beginning with the origin of cryptocurrencies and the dominance of Bitcoin with its USD 1.23 trillion market capitalization, the paper highlights popular online platforms facilitating Bitcoin trading. It also examines the varying legal statuses and regulations across different countries, with a notable divide between Eastern and Western nations, attributed to factors like wealth, risk tolerance, and government restrictions. The role of blockchain technology as the foundation of cryptocurrencies is explained, emphasizing its role in ensuring secure and transparent transactions. The paper delves into the processes involved in handling cryptocurrencies, including the blockchain, exchanges, wallets, and mining. Consumer behavior and the factors influencing cryptocurrency usage are analyzed, with a focus on speculation, algorithm trust, spending power, and demographics. Survey findings and case studies from diverse geographical areas reveal patterns of adoption and local consumer perceptions. The paper concludes by discussing the cryptocurrency market’s inherent volatility and sensitivity to regulatory changes, as well as the different types of cryptocurrencies and online exchanges shaping this evolving financial landscape. Overall, it offers insights into the complex dynamics surrounding cryptocurrency adoption and its potential impact on global finance.
Enhancing Landfill Monitoring and Assessment: A Proposal Combining GIS-Based Analytic Hierarchy Processes and Fuzzy Artificial Intelligence
Authors: Loureiro Anna Isabel Silva , Bressane Adriano , Nascimento Victor Fernandez , Simões José Victor Orlandi , Negri Rogério Galante
Published: October 2023

The global surge in urbanization and population growth has led to a significant increase in municipal solid waste generation, posing a considerable challenge in identifying suitable landfill sites. This study proposes a novel framework that enhances landfill site monitoring and assessment by combining GIS-based hierarchical analytical processes with a fuzzy inference system (FIS). The study employs a systematic approach involving phases such as feature selection, spatial analysis, criteria weighting, FIS building, and a case study conducted in São Paulo State, Brazil. The proposed framework effectively assesses landfill suitability and offers practical recommendations for landfill management and future site selection. This framework provides actionable recommendations for landfill monitoring and assessment, supporting landfill management while minimizing environmental and social impacts. It offers a comprehensive approach to landfill assessment, enhancing the sustainability of waste management practices. Further research can improve the proposed framework by refining feature selection and incorporating real-time data for continuous monitoring. Additionally, exploring the integration of emerging technologies, such as remote sensing and artificial intelligence, can further enhance landfill site monitoring and assessment.
Multi-Temporal Change of LULC and Its Impact on Carbon Storage in Jiangsu Coastal, China
Authors: Yuan Huanhuan , Zhang Jianliang , Wang Zhi , Qian Zhedong , Wang Xiaoyue , Xu Wanggu , Zhang Haonan
Published: October 2023

Coastal is the coupling of socio-economic and fragile ecosystems area existing development and protection problems, with lots of reserve land resources (i.e., bottomland and tidal flats). Analyzing and predicting the carbon storage changes caused by land use/land cover (LULC) on the Jiangsu coast were critical for revealing the potential problems of land surface changes and sustainable development. Then, we utilized the single dynamic degree and transfer in/out contribution, exploring the characteristics of LULC change in the study area from 1980 to 2018. Using the InVEST model, PLUS-LEAS model, and PLUS-Markov chain module, we assessed the spatiotemporal of the study area at the county level to reveal the LULC change strategy and driving factor contribution, as well as the composition of LULC and carbon storage in 2036. The results show that the LULC structure in the study area significantly changed from 1980 to 2018, in which the tidal flat and high coverage grassland decreased by 552.84 km2 and 383.71 km2 while the reservoir ponds and urban residential land increased by 1210.69 km2 and 101.70 km2. The major driving factor of LULC change has shifted from a single-factor to multi-factor coupling, and the influence contribution of human activity increased by 6.73%, especially the population. The carbon storage of study areas showed a significant decrease trend during 1980–2010, followed by a slight increase during 2010–2018. High-density carbon storage was mainly distributed in Lianyungang and Nantong and presented a decreasing trend along the coastline extending inland. The dry land and reservoir ponds are the main composition of LULC types in 2036, and the carbon storage increased to 2.39 × 108 t. In addition, more than decades of LULC change will cover part or all of the land use change process and trends, especially high-covered grasslands, so we suggest a 10-year LULC change to analyze coastal areas with lots of tidal flats and bottomlands. Therefore, this study can provide reference and theoretical guidance for ecologically sustainable development and future LULC evolution in coastal cities.
Early Warnings and Perceived Climate Change Preparedness among Smallholder Farmers in the Upper West Region of Ghana
Authors: Pienaah Cornelius K. A. , Batung Evans , Saaka Suleman Ansumah , Mohammed Kamaldeen , Luginaah Isaac
Published: October 2023

The impacts of climate change are already pushing beyond the threshold for sustainable agriculture and rural livelihoods. In Sub-Saharan Africa, smallholder farmers are particularly vulnerable due to limited resources and adaptive capacity. Early warnings are critical in mitigating and reducing climate-related dangers and building resiliency. That notwithstanding, there needs to be higher coverage of early warnings in developing countries, and there is even less knowledge of their contribution to rural development. Using a cross-sectional survey involving smallholder farmer households (n = 517), this study investigates the relationship between early warnings and perceived climate preparedness in Ghana’s semi-arid Upper West Region. From ordered logistic regression presented as an odds ratio (OR), factors that influenced climate preparedness in the past 12 months before the study include exposure to early warnings (OR = 2.238; p < 0.001) and experiences of prior climate events such as drought (OR = 9.252; p < 0.001), floods (OR = 6.608; p < 0.001), and erratic rain (OR = 4.411; p < 0.001). The results emphasize the importance of early warning systems and various socioeconomic factors in improving the climate resilience of smallholder farmers in Ghana. In conclusion, the study puts forth policy suggestions worth considering.
Estimation of Landslide and Mudslide Susceptibility with Multi-Modal Remote Sensing Data and Semantics: The Case of Yunnan Mountain Area
Authors: Yang Fan , Men Xiaozhi , Liu Yangsheng , Mao Huigeng , Wang Yingnan , Wang Li , Zhou Xiran , Niu Chong , Xie Xiao
Published: October 2023

Landslide and mudslide susceptibility predictions play a crucial role in environmental monitoring, ecological protection, settlement planning, etc. Currently, multi-modal remote sensing data have been used for precise landslide and mudslide disaster prediction with spatial details, spectral information, or terrain attributes. However, features regarding landslide and mudslide susceptibility are often hidden in multi-modal remote sensing images, beyond the features extracted and learnt by deep learning approaches. This paper reports our efforts to conduct landslide and mudslide susceptibility prediction with multi-modal remote sensing data involving digital elevation models, optical remote sensing, and an SAR dataset. Moreover, based on the results generated by multi-modal remote sensing data, we further conducted landslide and mudslide susceptibility prediction with semantic knowledge. Through the comparisons with the ground truth datasets created by field investigation, experimental results have proved that remote sensing data can only enhance deep learning techniques to detect the landslide and mudslide, rather than the landslide and mudslide susceptibility. Knowledge regarding the potential clues about landslide and mudslide, which would be critical for estimating landslide and mudslide susceptibility, have not been comprehensively investigated yet.
High Risk of Heart Tumors after COVID-19
Authors: Mitrofanova Lubov , Makarov Igor , Goncharova Ekaterina , Makarova Taiana , Starshinova Anna , Kudlay Dmitry , Shlaykhto Evgeny
Published: October 2023

An emergence of evidence suggests that severe COVID-19 is associated with an increased risk of developing breast and gastrointestinal cancers. The aim of this research was to assess the risk of heart tumors development in patients who have had COVID-19. Methods: A comparative analysis of 173 heart tumors was conducted between 2016 and 2023. Immunohistochemical examination with antibodies against spike SARS-CoV-2 was performed on 21 heart tumors: 10 myxomas operated before 2020 (the control group), four cardiac myxomas, one proliferating myxoma, three papillary fibroelastomas, two myxofibrosarcomas, one chondrosarcoma resected in 2022–2023. Immunohistochemical analysis with antibodies against CD34 and CD68 was also conducted on the same 11 Post-COVID period heart tumors. Immunofluorescent examination with a cocktail of antibodies against spike SARS-CoV-2/CD34 and spike SARS-CoV-2/CD68 was performed in 2 cases out of 11 (proliferating myxoma and classic myxoma). Results: A 1.5-fold increase in the number of heart tumors by 2023 was observed, with a statistically significant increase in the number of myxomas. There was no correlation with vaccination, and no significant differences were found between patients from 2016–2019 and 2021–2023 in terms of gender, age, and cardiac rhythm dis-orders. Morphological examination revealed the expression of spike SARS-CoV-2 in tumor cells, endothelial cells, and macrophages in 10 out of 11 heart tumors. Conclusion: The detection of SARS-CoV-2 persistence in endothelium and macrophages as well as in tumor cells of benign and malignant cardiac neoplasms, the increase in the number of these tumors, especially cardiac myxomas, after the pandemic by 2023 may indicate a trend toward an increased risk of cardiac neoplasms in COVID-19 patients, which re-quires further research on this issue and a search for new evidence.
Effect of Recycling on the Mechanical Properties of 6000 Series Aluminum-Alloy Sheet
Authors: De Caro Daniele , Tedesco Michele Maria , Pujante Jaume , Bongiovanni Andrea , Sbrega Giovanni , Baricco Marcello , Rizzi Paola
Published: October 2023

Sustainability is one of the biggest values of today and for the future of our society; a responsible usage of material in every sector is fundamental to achieving sustainability goals. Aluminum alloys are some of the most promising materials in terms of strength and weight, but their production implies the emission of a high amount of CO2. For that reason, the study and development of aluminum alloys with increasing scrap content play a central role in future applications. In the current study, two sheet-aluminum 6181 alloys with different scrap content were analyzed and compared with a 6181 alloy coming from primary production. The alloys were compared in terms of chemical composition, microstructure, tensile properties, and forming behaviors. The results showed that the alloys coming from secondary productions contained a higher amount of manganese, iron, and copper. The metallurgical and mechanical behaviors were very similar to those of the primary produced alloy. Nevertheless, a drop in formability was shown in the aluminum alloys containing a high scrap amount when stressed in a biaxial condition. The study demonstrated the viability of 6181 alloy production using a high scrap amount, highlighting the main difference with the same alloy coming from primary route production.
The Properties and Microstructure of Na2CO3 and Al-10Sr Alloy Hybrid Modified LM6 Using Ladle Metallurgy Method
Authors: Ervina Efzan Mhd Noor , Kong Hao Jie
Published: October 2023

In this work, Al-10Sr alloy and Na2CO3 were added to LM6 (reference alloy) as hybrid modifiers through ladle metallurgy. The microstructure enhancement was analyzed using an optical microscope (OM). The results were further confirmed with Scanning Electron Microscope (SEM) and Energy Dispersive X-ray (EDX) spectroscopy. The results showed that Na2CO3 and Al-10Sr alloy successfully hybrid modified the sharp needle-like eutectic Si into fibrous eutectic Si. Soft primary Al dendrites were also discovered after the hybrid modification. The formation of β-Fe flakes was suppressed, and α-Fe sludge was transformed into Chinese script morphology. A 2.13% density reduction was recorded. A hardness test was also performed to investigate the mechanical improvement of the hybrid-modified LM6. 2.3% of hardness reduction was recorded in the hybrid-modified LM6 through ladle metallurgy. Brittle cracks were not observed, while ductile pile-ups were the main features that appeared on the indentations of hybrid-modified LM6, indicating a brittle to ductile transformation after hybrid modification of LM6 by Na2CO3 and Al-10Sr alloy through ladle metallurgy.
Kinetics of Nickel Diffusion into Austenitic Stainless Steels AISI 304 and 316L and Calculation of Diffusion Coefficients
Authors: Bukovská Šárka , Moravec Jaromír , Švec Martin
Published: October 2023

Diffusion bonding has many advantages, but it also has its specifics. When creating heterogeneous joints, problems arise with the creation of intermetallic phases. For this reason, an interlayer is needed to prevent the creation of these unfavorable phases. It is important to ensure that the interlayer is of sufficient thickness to prevent the elements from diffusing through the entire interlayer and the intermetallic phases from being formed again. Conversely, too thick an interlayer causes an increase in the heterogeneity of the bond properties. The creation of the initial diffusion bonds in a heterogeneous diffusion joint of AISI 304 and AISI 316L steel with a 0.2 mm thick nickel interlayer was made in a Gleeble 3500. The experiments to determine the diffusion kinetics were carried out in a vacuum furnace, with subsequent evaluation by EDX (Energy Dispersive X-ray Spectroscopy) analysis. Subsequently, the diffusion coefficients of nickel into both steels were determined, and generalized equations were formulated to calculate the diffusion coefficients for temperatures in the range of 950 to 1150 °C and holding times in the range of 3600 to 18,000 s. Equations are also given to determine the width of the diffused zone between each steel and the Ni interlayer.
Thermo-Mechanical Treatment for Reducing the Wear Rate of CuCrZr Tool Electrodes during Electro-Discharge Machining
Authors: Skiba Jacek , Kulczyk Mariusz , Przybysz-Gloc Sylwia , Skorupska Monika , Smalc-Koziorowska Julita , Kobus Mariusz , Nowak Kamil
Published: October 2023

The research presented in this paper focused on optimising the process of unconventional plastic forming by hydrostatic extrusion (HE) with post-processing heat treatment of a copper alloy (CuCrZr) for electro-discharge machining (EDM) applications. The treatment was carried out in such a way as to obtain a material with an improved microstructure, characterised by a significant increase in hardness and strength while maintaining a high electrical conductivity, thus achieving the main goal of reducing electrode wear in the EDM process. As part of the research, a material with an ultrafine-grained structure was obtained with an average grain size of d2 = 320 nm and a much higher strength of UTS = 645 MPa compared to the material in the initial state (UTS = 413 MPa). The post-processing treatment (ageing) allowed us to obtain a material with a high electrical conductivity after the HE process, at 78% IACS. The electrodes made of CuCrZr subjected to HE had a reduced electrical discharge wear in relation to electrodes made of the initial material. The best results were obtained for electrodes made of the material subjected to a five-stage HE process combined with ageing at 480 °C for 1 h. The electrical discharge wear in these electrodes was reduced by more than 50% compared to electrodes made of non-deformed copper.
Performance Prediction of Hybrid Bamboo-Reinforced Concrete Beams Using Gene Expression Programming for Sustainable Construction
Authors: Waqas Hafiz Ahmed , Bahrami Alireza , Sahil Mehran , Poshad Khan Adil , Ejaz Ali , Shafique Taimoor , Tariq Zain , Ahmad Sajeel , Özkılıç Yasin Onuralp
Published: October 2023

The building and construction industry’s demand for steel reinforcement bars has increased with the rapid growth and development in the world. However, steel production contributes to harmful waste and emissions that cause environmental pollution and climate change-related problems. In light of sustainable construction practices, bamboo, a readily accessible and eco-friendly building material, is suggested as a viable replacement for steel rebars. Its cost-effectiveness, environmental sustainability, and considerable tensile strength make it a promising option. In this research, hybrid beams underwent analysis through the use of thoroughly validated finite element models (FEMs), wherein the replacement of steel rebars with bamboo was explored as an alternative reinforcement material. The standard-size beams were subjected to three-point loading using FEMs to study parameters such as the load–deflection response, energy absorption, maximum capacity, and failure patterns. Then, gene expression programming was integrated to aid in developing a more straightforward equation for predicting the flexural strength of bamboo-reinforced concrete beams. The results of this study support the conclusion that the replacement of a portion of flexural steel with bamboo in reinforced concrete beams does not have a detrimental impact on the overall load-bearing capacity and energy absorption of the structure. Furthermore, it may offer a cost-effective and feasible alternative.
Design and Implementation of a Recursive Feedforward-Based Virtual Reference Feedback Tuning (VRFT) Controller for Temperature Uniformity Control Applications
Authors: Araque Juan Gabriel , Angel Luis , Viola Jairo , Chen Yangquan
Published: October 2023

Data-driven controller synthesis methods use input/output information to find the coefficients of a proposed control architecture. Virtual Reference Feedback Tuning (VRFT) is one of the most popular frameworks due to its simplicity and one-shoot synthesis style based on open-loop system response for classic regulators such as PI or PID. This paper presents a recursive VRFT framework to extend VRFT into high-order controllers with more complex structures. The framework first defines a reference model and controller structure, then uses the open-loop data to compute the virtual reference and error signals, and, finally, uses these to find the controller parameters via an optimization algorithm. Likewise, the recursive VRFT controller performance is improved by adding a model-based feedforward loop to improve reference signal tracking. The recursive method is tested to design a temperature uniformity control system. The obtained results show that the recursive VRFT with a feedforward improves the system response while allowing more complex controller synthesis.
An Analytical Approach for Temporal Infection Mapping and Composite Index Development
Authors: Wang Weiwei , Weng Futian , Zhu Jianping , Li Qiyuan , Wu Xiaolong
Published: October 2023

Significant and composite indices for infectious disease can have implications for developing interventions and public health. This paper presents an investment for developing access to further analysis of the incidence of individual and multiple diseases. This research mainly comprises two steps: first, an automatic and reproducible procedure based on functional data analysis techniques was proposed for analyzing the dynamic properties of each disease; second, orthogonal transformation was adopted for the development of composite indices. Between 2000 and 2019, nineteen class B notifiable diseases in China were collected for this study from the National Bureau of Statistics of China. The study facilitates the probing of underlying information about the dynamics from discrete incidence rates of each disease through the procedure, and it is also possible to obtain similarities and differences about diseases in detail by combining the derivative features. There has been great success in intervening in the majority of notifiable diseases in China, like bacterial or amebic dysentery and epidemic cerebrospinal meningitis, while more efforts are required for some diseases, like AIDS and virus hepatitis. The composite indices were able to reflect a more complex concept by combining individual incidences into a single value, providing a simultaneous reflection for multiple objects, and facilitating disease comparisons accordingly. For the notifiable diseases included in this study, there was superior management of gastro-intestinal infectious diseases and respiratory infectious diseases from the perspective of composite indices. This study developed a methodology for exploring the prevalent properties of infectious diseases. The development of effective and reliable analytical methods provides special insight into infectious diseases’ common dynamics and properties and has implications for the effective intervention of infectious diseases.
On System of Root Vectors of Perturbed Regular Second-Order Differential Operator Not Possessing Basis Property
Authors: Sadybekov Makhmud , Imanbaev Nurlan
Published: October 2023

This article delves into the spectral problem associated with a multiple differentiation operator that features an integral perturbation of boundary conditions of one specific type, namely, regular but not strengthened regular. The integral perturbation is characterized by the function px, which belongs to the space L20,1. The concept of problems involving integral perturbations of boundary conditions has been the subject of previous studies, and the spectral properties of such problems have been examined in various early papers. What sets the problem under consideration apart is that the system of eigenfunctions for the unperturbed problem (when px≡0) lacks the property of forming a basis. To address this, a characteristic determinant for the spectral problem has been constructed. It has been established that the set of functions px, for which the system of eigenfunctions of the perturbed problem does not constitute an unconditional basis in L20,1, is dense within the space L20,1. Furthermore, it has been demonstrated that the adjoint operator shares a similar structure.
Locating Anchor Drilling Holes Based on Binocular Vision in Coal Mine Roadways
Authors: Lei Mengyu , Zhang Xuhui , Dong Zheng , Wan Jicheng , Zhang Chao , Zhang Guangming
Published: October 2023

The implementation of roof bolt support within a coal mine roadway has the capacity to bolster the stability of the encompassing rock strata and thereby mitigate the potential for accidents. To enhance the automation of support operations, this paper introduces a binocular vision positioning method for drilling holes, which relies on the adaptive adjustment of parameters. Through the establishment of a predictive model, the correlation between the radius of the target circular hole in the image and the shooting distance is ascertained. Based on the structural model of the anchor drilling robot and the related sensing data, the shooting distance range is defined. Exploiting the geometric constraints inherent to adjacent anchor holes, the precise identification of anchor holes is detected by a Hough transformer with an adaptive parameter-adjusted method. On this basis, the matching of the anchor hole contour is realized by using linear slope and geometric constraints, and the spatial coordinates of the anchor hole center in the camera coordinate system are determined based on the binocular vision positioning principle. The outcomes of the experiments reveal that the method attains a positioning accuracy of 95.2%, with an absolute error of around 1.52 mm. When compared with manual operation, this technique distinctly enhances drilling accuracy and augments support efficiency.
A Comprehensive Analysis of the Impact of Inorganic Matter on Membrane Organic Fouling: A Mini Review
Authors: Gao Qiusheng , Duan Liang , Jia Yanyan , Zhang Hengliang , Liu Jianing , Yang Wei
Published: October 2023

Membrane fouling is a non-negligible issue affecting the performance of membrane systems. Particularly, organic fouling is the most persistent and severe form of fouling. The complexation between inorganic and organic matter may exacerbate membrane organic fouling. This mini review systematically analyzes the role of inorganic matter in membrane organic fouling. Inorganic substances, such as metal ions and silica, can interact with organic foulants like humic acids, polysaccharides, and proteins through ionic bonding, hydrogen bonding, coordination, and van der Waals interactions. These interactions facilitate the formation of larger aggregates that exacerbate fouling, especially for reverse osmosis membranes. Molecular simulations using molecular dynamics (MD) and density functional theory (DFT) provide valuable mechanistic insights complementing fouling experiments. Polysaccharide fouling is mainly governed by transparent exopolymer particle (TEP) formations induced by inorganic ion bridging. Inorganic coagulants like aluminum and iron salts mitigate fouling for ultrafiltration but not reverse osmosis membranes. This review summarizes the effects of critical inorganic constituents on fouling by major organic foulants, providing an important reference for membrane fouling modeling and fouling control strategies.