bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Dosis dan Waktu Pemberian Pupuk NPK Majemuk Terhadap Pertumbuhan dan Hasil Buncis Manis (Phaseolus vulgaris L.)
Authors: T Simorangkir Exaudi Kirana , Barunawati Nunun
Published: August 2022

Buncis merupakan salah satu produk hortikultura yang banyak diminati oleh masyarakat karena memiliki kandungan gizi yang bermanfaat bagi kesehatan. Tujuan dari penelitian ini adalah untuk mempelajari interaksi dosis dan waktu pemberian pupuk NPK majemuk terhadap pertumbuhan dan hasil tanaman buncis, mempelajari pengaruh aplikasi dosis pupuk NPK majemuk terhadap pertumbuhan dan hasil tanaman buncis, dan mempelajari pengaruh waktu pengaplikasian pupuk NPK majemuk terhadap pertumbuhan dan hasil tanaman buncis. Penelitian dilaksanakan pada Agustus sampai November 2021, di Lahan Percobaan dengan ketinggian berkisar 460 meter diatas permukaan laut dengan suhu rata-rata berkisar antara 20°C-28°C. Penelitian menggunakan Rancangan Acak Kelompok (RAK) yang terdiri atas 9 perlakuan dengan 2 faktor. Hasil penelitian menunjukkan bahwa terdapat interaksi antara perlakuan dosis dan waktu aplikasi pupuk NPK majemuk terhadap pertumbuhan tanaman buncis. Pada parameter pertumbuhan, parameter yang berbeda nyata dan memiliki interaksi yaitu pada parameter panjang tanaman, jumlah daun, jumlah ruas, dan luas daun. Parameter pertumbuhan yang tidak memiliki pengaruh yang berbeda nyata yaitu pada parameter jumlah daun 21 HST dan jumlah ruas pada 12 dan 35 HST. Sedangkan hasil tertinggi dan pengaruh nyata pada hasil panen tanaman buncis diperoleh dari pemberian dosis pupuk NPK 300 kg ha-1 (P2) dengan waktu aplikasi saat tanam (W1) pada parameter jumlah bunga, jumlah polong, dan bobot polong sedangkan pada parameter panjang polong hasil tertinggi diperoleh pada dosis 250 kg ha-1 (P1) dan waktu aplikasi saat tanam, 7 HST dan 14 HST (W3).
Editorial Temas Agrarios Volumen 26(2) 2021
Authors: Temas Agrarios Revista
Published: August 2022

Editorial Temas Agrarios Volumen 26(2) de 2021
Current Evidence on the Use of mHealth Approaches in Sub-Saharan Africa: A Systematic Review (Preprint)
Authors: Aboye Genet Tadese , Vande Walle Martijn , Simegn Gizeaddis Lamesgin , Aerts Jean-Marie
Published: August 2022

BACKGROUND

Mobile health (mHealth) approaches are transforming the way healthcare is delivered to patients. This approach is especially beneficial to Sub-Saharan Africa (SSA), which has a disproportionate disease burden and a scarcity of healthcare workers. Evidence-based data on the use and implementation of mHealth approaches in the region is required to trace implementation and fill the existing gaps.

OBJECTIVE

The purpose of this study is to determine the current availability of mHealth interventions in SSA, the stage of these interventions, and the health issues mostly addressed by the interventions.

METHODS

Articles published from 2000 to 2021 were searched in four databases: PUBMED, IEEE, SCOPUS, and Web of Science. A set of inclusion and exclusion criteria was used to evaluate the articles. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method was used to assess the current evidence on the use and implementation of mHealth in the SSA. Using a data graphing table, data from the included publications were retrieved, and the data was then used and synthesized as the basis for analysis.

RESULTS

There were a total of 1020 articles found in the literature search. 59 of these have met the criteria for inclusion. The results show the implementation of mHealth interventions in 21 SSA nations. Only one (2%) of the reported interventions used a wearable sensor-based approach. Of these interventions, 13 (22%) were SMS text-based interventions, 17 (29%) were app-based mHealth approaches, 18 (30%) were telemedicine-based approaches, and 10 (17%) were mixed approaches. HIV, cancer, and maternal and child health problems are the most commonly discussed health issues in the literature covering mHealth in SSA. Proof of concept, design and development, a pilot test, a large-scale implementation, and a scale-up level of interventions were the most frequently documented stages of mHealth interventions.

CONCLUSIONS

Less than half of the 48 SSA countries are making (few) attempts to incorporate mHealth platforms into their health systems indicating the need for further developing mHealth technology in SSA. To encourage the adoption of the health system, mHealth solutions should be designed in a way that is both affordable and simple to use. Integrating wearable sensors into mHealth platforms should get careful consideration in order to monitor physiological indicators in real-time and provide patients with individualized care and treatment.
Reviewing the Secular Trend of COVID-19 Case Fatality Rate in Various Wave Variants from 2020 to 2022 in the United States and Corresponding Chronological Timeline of Pivotal Events (Preprint)
Authors: Li Jing-Xing , Wei James Cheng-Chung , Liao Pei-Luen , Yeh Chih-Jung
Published: August 2022

BACKGROUND

Coronavirus disease 2019 (COVID-19) has caused more than 640 million deaths worldwide.

OBJECTIVE

We aimed to investigate the mortality trend of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection from its outbreak in late 2019 up to the present.

METHODS

This cohort study assessed 2 693 458 adults diagnosed with COVID-19 at 48 healthcare organizations (HCOs) in the United States from January 1, 2020, to June 30, 2022. The inclusion criterion was the documentation of the International Classification of Diseases, 10th Revision, Clinical Modification (ICD–10–CM) codes or a positive result of the SARS-CoV-2 laboratory test.

RESULTS

Four sharp surges in the number of deaths and case fatality rate (CFR) from January 2020 to June 2022 were identified. The highest CFR occurred in January 2021 (0.28%). The mortality trends of both sexes positively correlated with the whole follow-up period. In a subgroup analysis, the CFR was always higher in males than in females. The CFR was age dependent, and older people had a higher CFR. Furthermore, racial disparity during the pandemic was remarkable. Regarding the survival rate at each wave of variants, Kaplan–Meier analysis revealed that Delta had a 1.671-fold cumulative mortality risk (95% confidence interval [Cl], 1.615–1.729) compared with Omicron on day 30. Delta also had a significantly increased mortality risk over Omicron in all age groups, except for ages below 19 years. For ages 0–18 years, mortality risk was highest in the Alpha wave. Death attributed by COVID-19 was age dependent for all age groups. Moreover, the CFR of ages above 80 years was as high as 17.33% across the study period.

CONCLUSIONS

This study is the first longitudinal study on COVID-19 fatality using the TriNetX dataset, and a comprehensive review of the literature and pivotal events on fatality fluctuations. Results suggest that age and male sex are strong mortality risk factors for COVID-19–infected patients. This study also further ascertained the CFR of each SARS-CoV-2 variant retrospectively. Additionally, nonpharmaceutical interventions seem important in lowering the CFR.

CLINICALTRIAL

none
Community-Engaged Participatory Methods to Address Lesbian, Gay, Bisexual, Transgender, Queer, and Questioning Young People’s Health Information Needs With a Resource Website: Participatory Design and Development Study (Preprint)
Authors: Delmonaco Daniel , Li Shannon , Paneda Christian , Popoff Elliot , Hughson Luna , Jadwin-Cakmak Laura , Alferio Jack , Stephenson Christian , Henry Angelique , Powdhar Kiandra , Gierlinger Isabella , Harper Gary W , Haimson Oliver L
Published: August 2022

BACKGROUND

Lesbian, gay, bisexual, transgender, queer, and questioning (LGBTQ+) young people (aged 15 to 25 years) face unique health challenges and often lack resources to adequately address their health information needs related to gender and sexuality. Beyond information access issues, LGBTQ+ young people may need information resources to be designed and organized differently compared with their cisgender and heterosexual peers and, because of identity exploration, may have different information needs related to gender and sexuality than older people.

OBJECTIVE

The objective of our study was to work with a community partner to develop an inclusive and comprehensive new website to address LGBTQ+ young people’s health information needs. To design this resource website using a community-engaged approach, our objective required working with and incorporating content and design recommendations from young LGBTQ+ participants.

METHODS

We conducted interviews (n=17) and participatory design sessions (n=11; total individual participants: n=25) with LGBTQ+ young people to understand their health information needs and elicit design recommendations for the new website. We involved our community partner in all aspects of the research and design process.

RESULTS

We present participants’ desired resources, health topics, and technical website features that can facilitate information seeking for LGBTQ+ young people exploring their sexuality and gender and looking for health resources. We describe how filters can allow people to find information related to intersecting marginalized identities and how dark mode can be a privacy measure to avoid unwanted identity disclosure. We reflect on our design process and situate the website development in previous critical reflections on participatory research with marginalized communities. We suggest recommendations for future LGBTQ+ health websites based on our research and design experiences and final website design, which can enable LGBTQ+ young people to access information, find the right information, and navigate identity disclosure concerns. These design recommendations include filters, a reduced number of links, conscientious choice of graphics, dark mode, and resources tailored to intersecting identities.

CONCLUSIONS

Meaningful collaboration with community partners throughout the design process is vital for developing technological resources that meet community needs. We argue for community partner leadership rather than just involvement in community-based research endeavors at the intersection of human-computer interaction and health.
The impact of covid-19 on the Tunisian supply chain: A case study (Preprint)
Authors: Elleuch Fadoi
Published: August 2022

BACKGROUND

Purpose: This article aims to provide rough orders of magnitude of the impact of the COVID-19 pandemic on the functioning of Tunisian businesses. Based on a sample of 192 Tunisian companies, the results showed a sharp contraction in inactivity due to the disruption of the various links in the supply chain following the generalized confinement of the population and the closure of borders.

OBJECTIVE

Findings: The findings suggest that the analysis of the results makes it possible to detect the manifest existence of specific operating models.

METHODS

Design/methodology/approach: We therefore sought to find out which links in the supply chain were the most impacted. To do this, the K-means offers the possibility of carrying out the analysis of variance (ANOVA).

RESULTS

By focusing on national companies, the study carried out sought to highlight the extent of the crisis on the country's economy. The results obtained confirmed the existence of a major impact on the operating activity of the Tunisian companies in the sample. 68% of the companies surveyed recorded deterioration in their activities and 29% of them experienced a severe decrease. To cope with the consequences of the crisis, three policies have been adopted to quantitatively and qualitatively adjust human resources to the needs of companies: temporary reduction in the workforce, Tele-working and dismissal.

CONCLUSIONS

The study then shed light on the situation of the supply chain of companies. Four behavior patterns were detected. Maintaining a fluid and regular relationship with suppliers and customers has pushed companies to implement technological solutions to manage flows and maintain the relationship.
However, the results of our research remain limited due to the low response rate from companies. The theoretical framework is not sufficiently referenced due to the novelty of the subject. Finally, we lack the necessary perspective on the consequences of the strategies adopted by companies. All of these limitations offer new avenues for future research.
COVID-19 is an exceptional event that has had a major impact on supply chains globally. The pandemic has highlighted the weight of the supply chain in the regular functioning of the global economy. It also highlighted the importance of taking into account new risks as well as the necessary mobilization of more technologically advanced tools to prepare for them.
The complexity of supply chains makes the development of commercial transactions fragile. This context offers, on another level, a multitude of opportunities for new structures and new business models.

CLINICALTRIAL

Post-COVID-19 is a major challenge for the national economic fabric. The crisis has encouraged the renewal of management methods. Working remotely and in collaborative mode, revising its processes, automating and securing them, making its information system agile and reliable… become the levers of operational excellence and a tremendous step forward.
Organic Food Production as a Necessity and Obligation of People in the 21st Century to Preserve Health, Biodiversity, and the Atmosphere the Position of Serbia on a Global Scale
Authors: Jelisijevic Ana Milojevic
Published: August 2022

Ever since the beginning of the existence of homo sapiens on the planet, from the initial basic diet of hunting, there was a gradual transition to using the gifts of nature from the plant world by collecting natural fruits, so that knowledge would lead man to planned cultivation. The initial primitive methods of land cultivation, including irrigation, did not have negative effects on the natural environment, as did the later cultivation of plants and the promotion of growth and yield with organic fertilizers. Only from the middle of the 20th century, when the race to increase yield became closer to the race for profit, was a negative imbalance observed, which directly affects human health and its environment. The continuous trend of increasing the crop, selection and modification of seeds and the use of nitrogen fertilizers, led to the loss of crop quality, especially from the health aspect, then the impact on the habitus and biodiversity of the wider environment, as well as the reduction of soil characteristics (humus layer). Economic crises also include food production, so the dilemma arises as to whether we should produce large quantities at any cost or rapidly switch to ecologically more justified organic production.In this modest study, a brief analysis of the relationship to basic foods in the human diet was carried out, with an emphasis on cereals, which were and remain a basic component, because in each historical period they represented the sources of about 20% of the calories and proteins necessary for human health, as well as the impact of healthy (organic) types of this cereal on the human environment. And then the quantity of organic food production in Serbia was analyzed.
An Assessment of Students’ Preferences Using Social Media Platforms on Their Selection of Private Universities in Lebanon
Authors: Bashir Eman , J. Hejase Hussin , Danash Kassem , Fayyad-Kazan Hassan , J. Hejase Ale
Published: August 2022

This paper assesses the behavior of prospective students of private universities in Lebanon on social media platforms; classifies them according to the extent and the way they use these platforms, and investigates students’ preferences using social media to choose a private University. A quantitative approach was adopted using a structured questionnaire administered to a convenient sample of 527 students from private universities in Lebanon who responded willingly. Collected data were analyzed using the SPSS program employing descriptive statistics. The university sample consisted of six Lebanese Higher Education Institutions that belong to different socio-economic categories, diverse cultures, many geographic locations, and varying chronological seniority. Results showed the influence of university pages on these platforms on students’ decisions and their adoption as a primary source of information before making their choices. Universities were unsuccessful in providing an effective communication channel with students or enabling two-way communication and motivating participation in comments, content creation, sharing experiences related to the universities, or sharing posts from their pages. Authors recommend universities review their motivational schemes for students to interact on university platforms regarding access to information and communication. For marketing, it is necessary to hire qualified staff, and provide a consistent and updated policy.
A Type of “Bubble” Water-saving Faucet
Authors: Luo Xiao , Nujoma Kandorera Angela , Kuang Xiying
Published: August 2022

At present, many places are seriously short of freshwater resources. Thus, saving water is the universal responsibility of contemporary citizens. Now faucet products such as ordinary washing nozzle, kitchen nozzle, face-washer nozzle, bathtub nozzle and washing machine nozzle are widely used in urban and rural households. Most have poor water-saving abilities, and much water is wasted through daily washing. Our bubble-type water-saving device is a brand-new water-saving device with a simple structure and low cost. It uses the Bernoulli principle and the bubble atomizing principle to inhale air naturally in water flow to atomize water flow. It can help achieve more than 50% water-saving efficiency in daily washing behavior.
DEEP REVIEW ON ALOPECIA AREATA DIAGNOSIS FOR HAIR LOSS-RELATED AUTOIMMUNE DISORDER PROBLEM
Authors: SAYYAD SHABNAM , MIDHUNCHAKKARAVARTHY DIVYA , SAYYAD FAROOK
Published: August 2022

Lots of women all over the globe are affected by thinning hair, and the number of females suffering from the disease is growing per year. Another important component in the development of thinning hair is genetics. One of the most important goals is to make a clinical condition. For example, in the area of medicine, categorization is critical since one of the primary goals of the doctor is to determine whether or not a patient suffers from an illness. Alopecia areata is a kind of chronic illness that causes baldness in the affected region. AA may cause baldness for a variety of causes thus, testing may be essential to confirm if it is the source of the loss of hair. Machine learning approaches have shown promise in a variety of fields, including dermatology, and may be useful in identifying alopecia areata for better prediction and diagnosis. Proper detection of an illness is also influenced by the fluctuating character of illness signs. Deep learning algorithms for identifying hair loss levels in males using facial pictures in this research. In this situation, a special training database, including face photos with varying degrees of baldness, has been generated. Furthermore, despite the limited accessibility of hairs in such images, a matching approach for mechanically categorizing face images to design categorization tables of male baldness from the medical field is provided. The outcomes of the experiments demonstrate the potential and efficiency for medical, security, and business apps. Related work in machine learning for hair illness categorization has also been addressed. The main objective of this study to analyze several machine learning and deep learning strategies for the identification of alopecia as well as in humans, as well as to determine the accuracy of extracting features methodologies.
COMPARATIVE STUDY OF SEMI-SOLID BASES OF NAPROXEN: PHARMACEUTICAL TECHNOLOGY ASPECTS
Authors: SRIVIDYA G. , NACHIYA R.A.M. JAINAF , EBRAHIM DOAA , EL-SAGHEER AIDA M. , KAYAROHANAM SAMINATHAN , JANAKIRAMAN ASHOK KUMAR , KHAN JIYAUDDIN , MOHAMED JAMAL MOIDEEN MUTHU
Published: August 2022

Objective: The main objectives of the present investigation work included that the preparation of a suitable naproxen semi-solid dosage form by using different types of semi-solid bases (gel bases, ointment bases) for topical application for the effective treatment of muscle aches.
Methods: Different types of semi-solid bases (gel bases and ointment bases) were successfully prepared by the incorporation method to know the effect of semi-solid bases on drug release from topical semi-solid formulations. In all formulations, the drug was added by the levigation method. An evaluation study of prepared formulations, includes physical appearance, spreadability, extrudability, pH was conducted according to official methods.
Results: Percent drug release of all formulations was conducted by taking diffusion cells with cellophane membrane and results showed that gel-based formulations showed more drug release than ointment-based formulations. Carbopol gel base (F1) showed more drug release (98.76 %), simple ointment base formulation (F8) showed least drug release (25.11%). From the stability studies reports at various temperature and humidity conditions it is evident that all formulations are stable for one month. In all the formulations, the drug content was observed at 95.75%.
Conclusion: Finally concluded that the NXN topical dosage forms can be prepared by using gel-type bases preferably than ointment bases to release more drug from formulations.
TICK-BORNE ZOONOTIC DISEASES AND ITS CONTROL
Authors: YADAV NIDHI , UPADHYAY RAVI KANT
Published: August 2022

The present review article explains different zoonotic diseases transmitted by various species of ticks. This article emphasizes various animal hosts, transmission and prevalence of various zoonotic diseases caused by a virus, bacteria, protozoans in different eco-climatic regions of the world. This article also explains various diagnostic methods applied for the detection of disease pathogens, treatment methods and prophylactic measures. It recommends tick saliva antigen-based oral vaccines and antibiotics as treatment methods. It also suggests use of various bait formulations and cultural control methods for deterring ticks from blood feeding. This article signifies the need of pesticides for control of ticks and tick-borne diseases.
MOLECULAR DOCKING AND COMPUTATIONAL PHARMACOKINETIC STUDY OF SOME NOVEL COUMARIN–BENZOTHIAZOLE SCHIFF’S BASE FOR ANTIMICROBIAL ACTIVITY
Authors: MADRIWALA BURHANUDDIN , JAYS JUDY , SAI G. CHAITANYA
Published: August 2022

Objective: The present study discusses molecular docking of some novel coumarin–benzothiazole Schiff bases and the prediction of pharmacokinetic properties of potent molecules by the computational method.
Methods: Five protein targets were selected for the study and their structures were taken from RCSB Protein Data Bank in PDB format. Preparation of proteins was done using Discovery Studio 2021 Client. A total of twenty derivatives were drawn using ChemDraw 20.0 and saved in Mol format. Molecular docking was performed using PyRx software. Docking results were visualized by Discovery Studio 2021 Client. The pharmacokinetic properties of the best compounds were determined using the pkCSM tool.
Results: All twenty derivatives were docked against the five proteins, namely DNA Ligase (PDB ID: 3PN1), Topoisomerase (PDB ID: 3TTZ), Sterol demethylase (PDB ID: 5FSA), Enoyl-acyl-carrier protein (PDB ID: 1BVR) and Glutamate racemase (PDB ID: 5HJ7). The compound JJB18 has shown the best binding score against DNA ligase (-10.7 kcal/mol), Glutamate racemase (-8.4 kcal/mol), and Enoyl-acyl-carrier protein (-10.8 kcal/mol). Further, compound JJB19 has shown the best score for fungal sterol demethylase (-10.6 kcal/mol) and compound JJB20 towards topoisomerase (-9.4 kcal/mol) than the standard drugs. The physicochemical properties of potent derivatives were also reported.
Conclusion: Molecular Docking study indicates that coumarin–benzothiazole Schiff bases may be effective inhibitors for the different microbial proteins. Additionally, in silico ADMET studies predicts drug-like features. Hence, these compounds may be considered lead molecules and further investigation of their analogues may help in the development of novel drugs for the treatment of microbial diseases.
Quality and Food Safety of Fishery Products Marketed in Selayar Islands Regency
Authors: Ariyani Ariyani , Amir Nursinah , Fahrul Fahrul
Published: August 2022

Food safety is an obligation that much be carried out by the food industry, especially in the fisheries sector to ensure that the products marketed are safe for consumption by consumers. Public safety and health must be protected from food that does not meet the requirements and from losses due to improper food production, distribution and trade. This study aims to identify the use of dangerous chemical materials like formalin and rhodamine B in processed fishery products, as well as to determine the origin of suppliers of products sold in the Selayar Islands Regency. The method used in this research was observation. Determination of the location and sampling used accidental sampling. Samples was taken from several traditional markets that sold fishery products in Selayar Islands Regency. The samples were analyzed the quality and safety parameters in the Laboratory of the Center Implementing the Quality of South Sulawesi Fisheries Products, the Laboratory for Animal Husbandry at Hasanuddin University, the Microbiology Laboratory Department of TPHP Pangkep, and the South Sulawesi Health Laboratory. The result shows that the parameters of quality and food safety products are in accordance with SNI and there is not used of formalin and rhodamine B in any fishery products.
Effect of spraying salicylic acid and biostimulant (Biomagic) on productivity and quality of pomegranate under heat stress in Siwa Oasis
Authors: Shaddad Amin M. G. E. , El-Hamied Sheren A. Abd
Published: August 2022

This study was implemented through the project (Sustainable development of fruit trees affected by some environmental stress in Matrouh governorate) funded by Regional Development Centers (RDC), Academy of Scientific Research and Technology (ASRT) (Call no. 2/2019/ASRT-RDC). It was carried out on 81 trees of Manfalouty pomegranate cv (Punica granatum) during the two successive seasons of 2020 and 2021 at the Khamisa research station of D.R.C. at Siwa Oasis-Matrouh Governorate-Egypt. The study aimed to investigate the influence of salicylic acid (SA) and the biostimulant biomagic to improve fruit productivity and the quality of pomegranate var. "Manfalouty." All the treatments were subjected to the same agricultural practice. The foliar treatments were used, tap water (T1), salicylic acid 100 ppm (T2), salicylic acid 200 ppm (T3), biomagic at 7.5 cm/l (T4), biomagic at 8.5 cm/l (T5), salicylic acid 100 ppm + biomagic 7.5 cm/l (T6), salicylic acid 100 ppm + biomagic 8.5cm/l (T7), salicylic acid 200 ppm. The obtained results showed that all the treatments were affected by spraying fruit trees with salicylic acid in combination with biomagic, followed by the solo concentrations of each treatment in both seasons. Meanwhile, T9 gave the best vegetative growth, fruit physical, chemical properties, and gave the lowest total acidity, fruit cracking percentage, and sunburn percentage in the 1st and 2nd season, respectively.
Proyectos de acuicultura en el Sistema de Evaluación de Impacto Ambiental.
Authors: Luengo Troncoso Sebastián , Díaz Chacón Federico
Published: August 2022

A critical analysis of the legal and practical configuration of aquaculture projects in the Environmental Impact Assessment System is offered. This is done from a study of the various environmental impacts associated with the execution of this type of projects, to then identify the administrative evaluation criteria. To this end, a statistical analysis of aquaculture projects in the Environmental Impact Assessment System is carried out. Thys analysis seeks to elucidate the main legal and material consequences and repercussions of the aforesaid evaluation.
Tissue engineering approaches for the repair and regeneration of the anterior cruciate ligament: towards 3D bioprinted ACL-on-chip
Authors:   University of Bern, Medical Faculty, Department for BioMedical Research (DBMR), Murtenstrasse 35, CH-3008 Bern, Switzerland, Bakirci E , Guenat OT , Ahmad SS , Gantenbein B
Published: August 2022

The anterior cruciate ligament (ACL) is the most frequently injured ligament in the knee. The current method to treat the injured ligament is reconstruction using autografts and allografts. Reconstruction requires the regeneration of ligament, bone and their interface to ensure proper recovery. Recently, researchers have focused on using tissue-engineered scaffolds made of synthetic materials and biomaterials —such as collagen, decellularised tissues, silk and synthetic polymers produced following different manufacturing methods — for ACL reconstruction,. Different materials can be easily processed using various fabrication methods for mimicking the mechanical properties of the ACL. The advances in technologies play an important role in the production of constructions that can mimic native ACL.. The present review addresses integrative scaffold design, different challenges in the potential materials and manufacturing methods as well as future strategies for ACL repair. Furthermore, the review provides a road map to 3D printing combined with organ-on-chip technology to demonstrate the potential for cost-effective and user-friendly fabrication methods for ACL engineering. Finally, it underlines the potential of 3D bioprinting and organ-on-chip technologies for micro-engineering of ligaments and their associated environment.
Biometric Vehicle Ignition System
Authors: Pani M Srujan , Manideep K , Rakesh R , Swapna T. , Chandrashekhar Dr. S.N.
Published: August 2022

Abstract: The project's purpose is to develop a smart ignition security system. A fingerprint sensor is used for motorcycle access in the proposed system, and a relay will be used for controlling ignition. The fingerprint sensor is a dependable fingerprint sensor that collects accurate fingerprint data. For added convenience and security, it's designed to fit inside electrical devices. The device, which is secure, fast, and easy to use, replaces credentials, PINs, and other types of user authentication. The system's principal controlling device is a microcontroller. A fingerprints sensor, a relay, as well as an LCD display are all included. The Micro - controller acts as something of a passcode to the ignition if the fingerprint device's input is legitimate. The status will be displayed on the LCD. This brilliant achievement is accomplished with the help of a microcontroller. The micro - controller grants access to the ignition switch if the information from the fingerprint scanner is valid. The information is displayed on the LCD. A pic micro-controller with a strong c software developed in embedded 'C' code is used to carry out this innovative activity. If the user cannot be identified, the cam32 modules is triggered, which takes an image of them and transmits it to the owner.
Analysis of Financial Knowledge Factors, Financial Attitude and Financial Behavior Toward User Financial Technology (Fintech) Decisions At Mercu Buana University
Authors: Adiningsih Dwi , Irawati Rizka , Putri Tasya Andini
Published: August 2022

One of the latest technological developments in Indonesia is financial technology or Financial Technology (Fintech). In the current era of modern technology, the use of money in physical form has begun to be eliminated with more modern technology, namely digital wallets. Fintech payment offers an easy method of financial technology and the use of money that becomes more practical and efficient. Fintech is also seen as a new market that integrates finance and technology and replaces traditional financial structures with new technology-based processes. Fintech can provide services with ease and minimize costs compared to traditional methods that already exist. The purpose of this research is to find out how the influence of financial literacy on the decisions of users of financial technology (Fintech) in the city of West Jakarta. The sampling method in this study is a quantitative method with an associative approach. The sampling technique used in this study was non-probability sampling using accidental sampling.
The Effect Of Financial Literature, Financial Behavior, & Regret Aversion Bias On Millennial Investment Decisions
Authors: Octavia Anita Dwi , Yuwono Chyntia Chris , Monangin Filia Gabrilia
Published: August 2022

This study aimed to analyze the effects of financial literacy, financial behaviour and regret Aversion bias towards investment decisions among millennials in Indonesia. This study used primary data obtained by distributing questionnaires to 113 respondents with Maximum age of 30 years. The sampling method used in this research is purposive sampling. There were 78 out of 113 respondents who met the criteria to be sampled. The analysis method used in this study is Partial Least Square (PLS), with an R2 value of 98.50%. The results showed that financial behaviour had a significant positive effect on investment decisions while financial literacy and regret aversion bias were not affected.
dupla perspectiva documentária e a formação de identidades em Adoniran Barbosa
Authors: Lemos Jr Urbano , Gosciola Vicente
Published: August 2022

O artigo aborda a importância do documentário imagético e sonoro para debater os desafios do nosso presente. O filme analisado é Adoniran – Meu nome é João Rubinato (2018), de Pedro Serrano. As músicas analisadas trazem temas como imigração, verticalização, metropolização, despejo, diferenças sociais e apontam as transformações a partir da estruturação urbano-industrial da cidade de São Paulo. O estudo se ampara no conceito de voz no documentário a partir de Bill Nichols. A metodologia compreende a análise das músicas: Saudosa Maloca (1951), Abrigo de Vagabundo (1959) e Despejo na Favela (1969). O objetivo do artigo é propor a reflexão do documentário como uma forma criadora de significados e sentidos que emanam da história e dos contextos socioculturais. Conclui-se que a perspectiva documentária se dá por meio das experiências dos sujeitos e do imaginário das culturas.
Diálogos no Cinema
Authors: Ribeiro de Sousa Luciene , Tereza Farias de Oliveira Catarina
Published: August 2022

O artigo apresenta uma investigação que problematiza formas de ver e pensar  a  exibição  de filmes para estudantes do 9º ano da rede pública municipal de Fortaleza. A pesquisa se desenvolveu junto ao projeto integração no Cuca (Centro Urbano de Cultura, Arte, Ciência e Esporte) na Barra do Ceará. Ao identificarmos que esse projeto colocava o cinema como parte das suas atividades educativas, nos propomos a observar como esse uso acontecia. A pesquisa envolve dois momentos: um primeiro que observa o uso de audiovisual e, um segundo, no qual propomos oficinas com os (as) adolescentes. A metodologia de pesquisa escolhida foi a etnografia militante, utilizando oficinas como estratégia de intervenção. Os resultados da pesquisa nos fizeram compreender que a exibição de cinema para adolescentes é fundamental em práticas educativas, mas precisa ocorrer de forma planejada e criativa  com dinâmicas que  facilitem a participação e a expressão dos (as) educandos (as).
modelo cognitivo como proceso semiósico
Authors: Campos Arturo Morales
Published: August 2022

Abordar el tema de las imágenes mentales resulta un tema arriesgado, pues, dentro de las neurociencias, existen posiciones que rechazan fuertemente tal fenómeno por ser subjetivo en extremo. Sin embargo, es algo que debe estudiarse bajo diferentes perspectivas teóricas. La semiótica puede ser una herramienta útil en este sentido y, de manera concreta, la  semiosis, puesto que es un proceso cognitivo que, como se podrá sustentar, enlaza aspectos biológicos y culturales. En este trabajo, se establecerá un paralelismo entre imágenes mentales y modelos cognitivos para mostrar los componentes esenciales de estos últimos.
Spatial planning systems worldwide
Authors: Tosic Branka , Zivanovic Zora
Published: August 2022

The paper outlines the features of the spatial planning systems worldwide, on
different continents, based on countries where legislative frameworks for
the planning and methodology of preparing and implementing planning
documents are defined. In order to define global features of a spatial
planning systems it is necessary to address several issues: the
implementation of sustainability principles, the development of regional
planning, the importance of an urban planning approach, management system,
implementation problems, participation, the share of strategic spatial
planning and transnational cooperation, etc. The determination of the
planning system by numerous and various factors influenced the different
degree of development of the planning process. In many countries, planning
practice faces problems associated with the disrespect of the law,
corruption and illegal land use, resolving regional development imbalances
in almost all countries etc. At a global level, addressing environmental
issues is becoming a dominant goal in most planning systems.
The role of the southern Libyan Saharan cities in building their relations with neighbouring countires
Authors: Jarad Ali , Attwairi Almokhtar , Elaswed Tarek , Elmghirbi Elhadi
Published: August 2022

The southern Libyan cities (Ghat, Murzuq, and Al-Kufra) played their
political, economic, and social role in Libyan relations with neighbouring
countries during various historical phases. These cities paved the way for
building economic relations, especially the exchange of goods between North
and South Africa through Mediterranean ports to Europe. The main goal of
the research is to stress the role of the Saharan towns and cities in
building relations between Libya and neighbouring countries and to tracking
the political, economic and social impacts on Saharan cities, but also their
effects between the northern African region and southern Libya towards
African Sub-Saharan region. Additionally, it is important to explain the
role of southern cities geographically in the influx of illegal migration
of temporary transit and settlement areas and crossing north to Europe and
studying the impact of instability and insecurity after 2011 in the tribal
and ethnic conflict in southern Libyan region. The importance of the study
is based on identifying the political, economic, and social conditions of
southern Libyan region and its important historical cities.
Evaluation of the residential satisfaction via a factorial analysis of the residentia environment (social housing). The case of the city of Boussaâda, Algeria
Authors: Hadji Mohammed , Dib Belkacem
Published: August 2022

The improvement of the quality of life within the residential environment is
the ultimate objective of sustainable development, in which its
environmental, economic and social dimensions are constantly identified and
updated. To this end, the development of a reference framework for the
actors of the housing sector can formulate new policy trends related to the
planning and design of the residential environment. Post-occupancy
evaluation is an appropriate method for assessing and evaluating the impact
of housing policies on residents' behaviour. Then, the results of these
policies are tested by measuring residential satisfaction and by determining
the factors that affect it. To achieve this objective, the technique of a
head-of-household interview form was used. We relied on eighteen well-known
potential variables in studies related to housing satisfaction, focusing on
the social dimension. A sample consisting of two social housing clusters in
the city of Boussa?da, comprising 121 households was randomly selected.
Finally, the data were statistically processed using a factor analysis
which is the principal components method, through which four factors
containing fourteen variables that control residential satisfaction were
extracted.
Green chemical principles based regioselective functionalization of 2,4,6-trichloropyrimidine-5-carbaldehyde: Application in the synthesis of new pyrimidines and pyrrolopyrimidine
Authors: Udayasri Allu , Chandrasekhar Manchikanti , Naga Brahmeswararao , Varanasi Ganesh , Ramakrishna Duggirala
Published: August 2022

The present work reports the synthesis of three new nitrogen-containing heteronuclear molecules (two pyrimidines and one pyrrolopyrimidine). Based on the 12 principles of green chemistry, chemical methodologies are planned and executed. Various phase transfer catalysts were examined in the crucial step to execute C?N bond formation (through the SnAr mechanism), TBAI was found to be a better option than those of TBAB and CTAB. The one-pot synthetic methodology was optimized involving Wittig olefination and bromination to achieve a key precursor for the synthesis of a new pyrrolopyrimidine.
Fabry disease in Serbia - current status and future perspectives
Authors: Celic Dejan , Bozic Dusan , Ilic Tatjana , Knezevic Violeta , Golubovic Sonja , Zivkovic Sinisa , Ljubicic Bojana , Naumovic Radomir , Mitic Igor
Published: August 2022

nema
The levels of circulating long non-coding RNA GAS5 in prostate cancer patients: A single-center study
Authors: Misovic Miroslav , Aleksic Predrag , Kostic Dejan , Vukovic Miodrag , Radojicic Bojan , Rancic Nemanja , Cikota-Aleksic Bojana
Published: August 2022

Background/Aim. Prostate carcinoma (PCa) is second occurring carcinoma that affects the male population. Although PCa incidence rates are high, most cases have a favorable prognosis, with comfortable long-term life quality. The aim of the study was to compare long non-coding RNA (lncRNA) growth arrest-specific transcript 5 (GAS5) plasma levels between healthy individuals and patients with PCa, and also between PCa patients with different prognostic scores. Methods. The present study included a total of 40 patients with PCa and a control group of 20 healthy individuals. PCa patients were divided into two subgroups (20 patients each) based on the prognostic criteria of the American Joint Committee on Cancer. The patient data were collected and analyzed; lncRNA GAS5 levels were quantified using the re-al-time polymerase chain reaction method. Statistical analysis was conducted using the IBM SPSS Statistics 26.0 computer program (IBM, USA, 2019). Results. The relative quantification of lncRNA GAS5 expression levels showed down-regulation in PCa patients compared to healthy individuals; however, the difference was marginally statistically significant (p = 0.056). With further analysis of the given results, we concluded that the expression level of lncRNA GAS5 was not significantly different in the first patient subgroup and the healthy individuals (p = 0.268). Patients from the second subgroup had significantly lower plasma levels of lncRNA GAS5 than healthy individuals (p = 0.033). The difference in the level of lncRNA GAS5 expression between patients with favorable prognoses (Group 1) and the ones with worse prognostic scores (Group 2) did not indicate statistical significance (p = 0.275). In both Group 1 (p = 0.805) and Group 2 (p = 0.454), the plasma levels of lncRNA GAS5 were not significantly different in comparison to the age (? 65 vs. > 65 years). Conclusion. One of the main objectives of PCa research is identifying novel and more efficient biomarkers. Conducted research provides strong evidence about the significance of lncRNAs GAS5 in PCa, as well as the correlation between decreased expression of lncRNA GAS5 and poor prognosis in various tumors.
Method of controlling a group of unmanned aircraft for searching and destruction of objects using artificial intelligence elements
Authors:   Ivan Kozhedub Kharkiv National Air Force University, Tymochko O. , Trystan A. ,   Ivan Kozhedub Kharkiv National Air Force University, Matiushchenko O. ,   Ivan Kozhedub Kharkiv National Air Force University, Shpak N. ,   Lviv Polytechnic National University, Dvulit Z. ,   Lviv Polytechnic National University
Published: August 2022

The article develops a method of controlling a group of unmanned aerial vehicles to search for and destroy enemy objects. The method is to recognize situations and adjust the actions of the group according to it. The basis of the method is the use of an intelligent decision support system. It provides situation recognition, using image recognition materials (intelligence materials), generalization of the obtained information and its comparison with the elements of the set of descriptions of typical situations. The method of controlling a group of unmanned aerial vehicles to search for and destroy enemy objects is built according to the concept of multi-agent systems – intelligent agents – UAVs. The information technology of processes of the method of control of a group of unmanned aerial vehicles according to the IDEF0 methodology is developed.
The effect of artificial diet made of soybeans (Glycine max L.) on the rearing of Spodoptera frugiperda (Lepidoptera:Noctuidae)
Authors: Thamrin Sulaeha , Zuliana Nurul Syafira , Sjam Sylvia , Melina Melina
Published: August 2022

Spodoptera frugiperda is a novel invasive pest of maize crops. Therefore, studies on this pest are limited. Research on the use of artificial diets in S. frugiperda larvae rearing is essential to facilitate the provision of test larva stocks for lab-scale study purposes. The aim of this research was to figure out the effect of an artificial diet from soybeans as a protein source on S. frugiperda rearing. The parameters observed in this research were larval-stage longevity, larval survival rate, pupa size, sex ratio, pupal-stage longevity, pupal survival rate, fecundity, and nutritional index. The results showed that an artificial diet with soybeans had a significant effect on sex ratio, pupal survival rate, relative consumption rate (RCR) 4.89 g/g/day (4th instar); 1.99 g/g/day (5th instar), approximate digestibility (AD) 98.39% (4th instar); 95.45% (5th instar), and fecundity, but it did not have any significant effect on larval-stage longevity, larval survival rate, pupa size, pupal-stage longevity, the efficiency of conversion of ingested food (ECI) 3.68% (4th instar); 7.84% (5th instar), and efficiency of conversion of digested food (ECD) 3.76% (4th instar); 8.27% (5th instar). Artificial diet-based soybean was highly potential to be used in S. frugiperda rearing.
PENGARUH SUPLEMENTASI TEPUNG KROKOT (Portulaca oleracea) TERHADAP TOTAL SEL DARAH PUTIH DAN DIFERENSIAL SEL DARAH PUTIH KAMBING JAWARANDU (Capra aegagrus hircus)
Authors: Setiawan Fani , Erwanto Erwanto , Suharyati Sri , Siswanto Siswanto
Published: August 2022

Penelitian ini bertujuan untuk mengetahui pengaruh suplementasi tepung Krokot (Portulaca oleracea) terhadap total sel darah putih dan diferensial sel darah putih. Penelitian ini dilaksanakan pada Februari-Maret 2021 di Kelompok Ternak Rambon Asri, Desa Rejo Asri, Kecamatan Seputih Raman, Kabupaten Lampung Tengah, Provinsi Lampung. Pemeriksaan sel darah putih dan diferensial sel darah putih dilaksanakan di Balai Veteriner Lampung. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan 4 perlakuan dan 5 ulangan. Perlakuan yang diberikan yaitu ransum basal (P0), ransum basal dengan suplementasi 5% tepung Krokot (P1), ransum basal dengan suplementasi 10% tepung Krokot (P2), dan ransum basal dengan suplementasi 15% tepung Krokot (P3). Data yang diperoleh dianalisis menggunakan analisis ragam dengan taraf nyata 5% dan apabila diperoleh hasil berbeda nyata dilanjutkan dengan uji lanjut polinomial ortogonal untuk mengetahui dosis pemberian tepung Krokot terbaik dalam ransum. Hasil penelitian menunjukkan bahwa perlakuan suplementasi tepung Krokot berpengaruh nyata (P<0,05) terhadap total Neutrofil dan berpengaruh sangat nyata (P<0,01) terhadap total sel darah putih dan Limfosit, tetapi tidak berpengaruh nyata (P>0,05) terhadap Monosit. Didapatkan dosis terbaik suplementasi tepung Krokot optimum pada sel darah putih, Limfosit dan Neutrofil berturut-turut yaitu 3,01% kg/BK ransum, 8,34% kg/BK ransum, dan 10,51% kg/BK ransum.