bluuebunny/crossref_metadata_2025 huggingface dataset:
STUDY OF ENDOTHELIAL DYSFUNCTION INDICATORS IN RATS WITH EXPERIMENTAL PERITONITIS
Authors: Tsypovyaz S.V. , Vashuk R.G. R.G. , Sarakhan V.M. , Savуtskyi I.V. , Yeromenko R.F.
Published: May 2023

Background. In the structure of purulent complications, peritonitis, destructive lesions of abdominal organs, and, as a rule, advanced forms of these diseases occupy one of the first places - 15-25% of urgent surgical diseases are complicated by peritonitis. It is generally known that the leading role in the triggering mechanism of the development of peritonitis belongs to the systemic inflammatory reaction, a component of which is phagocytosis, cellular and humoral immunity. However, the results of research on the state of functional activity of the endothelium in experimental peritonitis are limited.

Aim: to study the activity of NO-synthase, FV and endothelin-1 in rats with experimental peritonitis.

Materials and methods. Experimental studies were conducted on 24 non-linear laboratory rats, which were divided into 2 groups: 1 group – intact control (animals received distilled water), 2 group – animals of the control pathology group. According to the "Methodological recommendations for preclinical study of medicinal products", experimental peritonitis was studied on the model of V. A. Lazarenko. Indicators of vascular-platelet and coagulation hemostasis were determined according to generally accepted methods. Indicators characterizing endothelial dysfunction were studied according to generally accepted methods.

Results. The most likely mechanism that is damaged in the endothelium during peritonitis is the activation of the synthesis of inducible NO-synthase by neutrophils/macrophages in response to infection. It is possible that the hyperproduction of nitric oxide, on the one hand, is aimed at destroying microflora and oxidizing toxins, and on the other hand, at suppressing the expression of tissue factor and cell adhesion molecules. platelet aggregation and cascade disorders in the hemostasis system. In animals with experimental peritonitis against the background of oxidative stress, there was an increase in the number of circulating desquamated endothelial cells in the blood, which is a highly specific marker of endothelial dysfunction. The level of the Willebrand factor also increased, which indicates the pathogenetic dependence of the factors that damage the endothelium of the vascular wall on the concentration of the Willebrand factor, which helps to reduce the permeability of blood vessels by adhesion of platelets to the endothelium. Confirmation of the development of endothelial dysfunction in peritonitis is an increase in the concentration of endothelin-1, which is a regulator of the process of vascular neoangiogenesis in response to endothelial damage.

Conclusion. Hyperproduction of nitric oxide not only reflects the processes that occur in the focus of vascular endothelium damage, but also affects the severity of the inflammatory process and the consequences of the disease.
MANIFESTATIONS AND COMPLICATIONS OF ROTAVIRUS-POSITIVE GASTROENTERITIS AND ROTAVIRUS-NEGATIVE GASTROENTERITIS IN PRESCHOOL CHILDREN
Authors: Kleshchuk А.А. , Kolotylo Т.R.
Published: May 2023

Background. The cumulative annual statistics of rotavirus-associated gastroenteritis are about 25 million outpatient visits, 2 million hospitalizations, and 180,000–450,000 deaths in children under 5 years of age.

Aim: To analyze the manifestations and complications of rotavirus compared with non-rotavirus gastroenteritis in UK children.

Materials and methods. A retrospective hospital-based case-control study was conducted at three sites in East London, Great Britain. Cases were children aged 1 month to 16 years who were diagnosed with acute gastroenteritis between June 1, 2011, and December 31, 2013, and who were positive for rotavirus by PCR (polymerase chain reaction) on stool virology. They were compared by age, gender and month of referral to a control group with rotavirus-negative gastroenteritis.

Results. Data were collected from 116 children (50 cases and 66 controls). Children with rotavirus gastroenteritis were more likely to have metabolic acidosis (pH 7.30 vs. 7.37) and fever (74% vs. 46%) and were more likely to require hospitalization compared with children with non-rotavirus gastroenteritis. (93% vs. 73%). Neurological complications were the most common extraintestinal manifestations, but did not differ significantly between children with rotavirus-positive gastroenteritis (RPG) and rotavirus-negative gastroenteritis (RNG) (24% vs. 15%, respectively). Encephalopathy occurred only in children with rotavirus infection.

Conclusion. Therefore, rotavirus is an important cause of morbidity and mortality in preschool children. Seizures and milder neurologic signs were common and associated with multiple pathogens, but encephalopathy occurred only in children with rotavirus-positive gastroenteritis (RPG). Timely vaccination against rotavirus can prevent serious consequences.
ANALYSIS OF THE DYNAMICS OF THE ASSORTMENT OF PESTICIDES PERMITTED FOR USE IN UKRAINE, THE PROCESSING OF WHICH IS POSSIBLE WITH THE USE OF AGRICULTURAL DRONES
Authors: Borysenko A.A. , Antonenko A.N. , Bardov V.G. , Kondratiuk M.V. , Podust A.O. , Omelchuk S.T.
Published: May 2023

Background. The use of unmanned aerial vehicles (UAVs, drones) in agriculture for the purpose of plant protection is becoming an increasingly popular innovative tool in countries around the world, thanks to the many advantages that this technology offers over the traditional aerial application method. However, this method of introduction can pose a number of risks for both the environment and human health.

Based on the need for registration or re-registration of chemical plant protection agents for their use with UAVs, we conducted an analysis of the range of pesticides registered in Ukraine for aerial application.

Aim: analysis of the dynamics of the assortment of pesticide formulations approved for use in Ukraine, processing of which is possible using agricultural drones.

Materials and methods. The object of the study was the dynamics of changes in the range of pesticide formulations, primarily those processing of which is possible by using of agricultural drones.

Analytical indicators of dynamics such as absolute growth (AG), compound annual growth rate (CAGR) and growth rate (CAGR) of pesticides were applied. Statistical data processing was carried out using the IBM SPSS Statistics Base v.22 license package and the MS Excel program (version 9.0, 2000).

Results. When conducting an analysis of the assortment of pesticides registered in Ukraine for use by the aerial method for the period 2010-2022, we found that the total number of herbicides has almost not changed: there were 20 in 2010, it became 22 in 2022. The number of fungicides has increased more than five times: from 4 in 2010 to 21 in 2022 and will make up 15.7% of the total in 2022. The number of insecticides and acaricides for aerial treatment in 2010 was 17, and in 2022 - 34, that is, it has doubled, which is 25.7%. The largest group of pesticides registered in Ukraine for aerial application is the group of desiccants, which doubled from 29 in 2010 to 57 in 2022 and makes up 42.5% as of 2022. When conducting an analysis of individual groups of pesticides, it was established that the rates of growth of herbicides - 10% (of which combined - 600%), insecticides and acaricides - 100% (of which combined - 60%), fungicides - 425% (of which combined - 500%), desiccants - 96.6%.

Conclusion. The registration of chemical plant protection products for use by UAVs is important in general, because this method has less negative impact on the health of workers and the state of the environment. In addition, the registration for such use of formulations for aerial treatment is relevant, as it is a perspective, effective and safe alternative to them.
Characteristic of Endometrial stromal sarcoma by algorithm of potential biomarkers for uterine mesenchymal tumor
Authors: Hayashi Takuma , Abiko Kaoru , Yaegashi Nobuo , Nishikawa Shoko , Konishi Ikuo
Published: May 2023

BACKGROUND/AIM: The benign tumor uterine leiomyoma derives from the smooth muscle tissue that constitutes the uterus. In contrast, the malignant tumor uterine sarcoma can derive from either smooth muscle or stroma, and differs from both uterine leiomyoma and endometrial cancer. Uterine sarcoma is broadly classified into three types: uterine leiomyosarcoma, endometrial stromal sarcoma, and carcinosarcoma. However, although uterine leiomyosarcoma and endometrial stromal sarcoma are both classified as uterine sarcoma, they differ significantly in their sites of occurrence, symptoms, and treatment methods, among other factors. Uterine leiomyosarcoma arises from the muscle tissue constituting the wall of the uterus and accounts for approximately 70% of all uterine sarcoma cases. Endometrial stromal sarcoma arises from the stromal tissue beneath the endometrium and accounts for approximately 25% of all uterine sarcoma cases. Endometrial stromal sarcoma is classified as either low-grade or high-grade.

MATERIALS AND METHODS: A patient’s symptoms suggested uterine sarcoma, transvaginal ultrasonography and endometrial biopsy or partial dilation and curettage were performed. However, in clinical practice, the sensitivity of those tests for detecting malignancy is limited, and endometrial stromal sarcoma and uterine leiomyosarcoma were diagnosed incidentally on histopathology examination of hysterectomy specimens or enucleated tumors.

RESULT: Histopathology examination of a surgical specimen from a patient who was thought to have submucosal uterine leiomyoma after contrast-enhanced magnetic resonance imaging (MRI) found that the patient actually had endometrial stromal sarcoma.

CONCLUSION: Despite the remarkable progress made in medical imaging technology, the accuracy of contrast-enhanced MRI for detecting uterine mesenchymal tumors is limited. Histopathologic diagnosis based on surgical specimens should therefore be performed when medical grounds for diagnosing a benign tumor on contrast-enhanced MRI are lacking.
The Relationship of Leadership Style and Organizational Climate to Job Burnout Levels Among Taiwan Public Secondary-School Teachers
Authors:   ,   Andrews University, Chi Jerry
Published: May 2023

Problem. This study is to examine the burnout levels of secondary-school teachers in Taiwan and to determine if leadership style, organizational climate, and demographic variables are related to teacher burnout. Methods. This quantitative research based on empirical data collection utilized the following instruments: (1) the Maslach Burnout Inventory (MBI), (2) the Leadership Behavior Description Questionnaire (LBDQ), and (3) the Organizational Climate Index (OCI). The four instruments are translated into Chinese and administered to 809 secondary teachers serving in Kaohsiung, Taiwan. Multiple regression and Analysis of Variance were used to determine what kind of leadership style and organizational climate factors, as perceived by teachers, would relate to teacher burnout. Results. Taiwan secondary-school teachers have high Emotional Exhaustion, moderate Depersonalization, and low Reduced Personal Accomplishment. The organizational climate is perceived to be a low Intellectual Climate, low Achievement Standard, low Personal Dignity, low Organization Effectiveness, low Orderliness, but high Impulse Control. The leadership style is perceived to have a high degree of Initiating Structure, but a low degree of Consideration, which are combined and defined as Telling or Authoritarian leadership style. Conclusion. Although teachers in Taiwan have large class size more than 40 students and average 8 hours overtime a week, a majority of teachers experience moderate burnout levels and only 8% experience a high burnout level. In the multiple regression model, Personal Dignity, Age, Consideration, Overtime, and Gender are associated with Emotional Exhaustion. Consideration, Personal Dignity, Age, and Overtime are associated with Depersonalization. Initiating Structure, Impulse Control, and Age are associated with Reduced Personal Accomplishment.
Interactional Effects Between Levels of Biofeedback Confidence and Measures of Assertiveness on Biofeedback Treatment Outcome
Authors:   ,   Andrews University, Clarke-Pine Dora
Published: May 2023

Problem. Not all individuals who enter a biofeedback program obtain the relief that they are seeking from their various pain-related or anxiety-related complaints. Some individuals obtain little or no relief, whereas others may eliminate their pain-related or anxiety-related complaints completely. Understanding more clearly the reasons for such variance is considered important in that such understanding may encourage the development of techniques that elicit greater biofeedback efficacy rates. This research study was an attempt to determine some of the factors that may help contribute to a successful biofeedback program. Specifically examined were interactional effects between levels of biofeedback confidence and measures of assertiveness on biofeedback treatment outcome. Method. The population included 40 patients who were referred to the biofeedback program at a military hospital in south-central Missouri. These were subjects who presented with either an anxiety-related or pain-related complaint. Subjects were administered the Gambrill Assertion Inventory, the Biofeedback Intervention Confidence Scale, and the Biofeedback Survey (pre-test/post-test). The pre-test, along with the first two instruments, were administered before treatment intervention and the post-test was administered after a standardized biofeedback treatment intervention ensued. A two-way ANCOVA design, using a fixed effects model, was utilized in the analysis of the resulting data. Results. No interactional effects between measures of assertiveness and biofeedback confidence on biofeedback treatment outcome were found. In addition, assertiveness levels did not appear to have a significant impact on biofeedback treatment outcome in terms of frequency or intensity of the presenting complaint. The only significant finding of the study, at the .05 level, was than an individual's confidence level in a biofeedback treatment program did have a significant impact upon treatment outcome in terms of "frequency" of presenting complaint. That is, a high level of biofeedback confidence had a significant impact on reducing the frequency of a presenting complaint. Conclusion. It was concluded that if a high level of confidence in a biofeedback program can have a positive and significant impact on biofeedback outcome in terms of "frequency" of presenting complaint, then increasing an individual's level of confidence in such an intervention would be viewed as cost-effective in terms of treatment.
Implementing Innovative Pedagogy in the First Course in Accounting and its Relationship to Student Attitudes Toward the Profession
Authors:   ,   Andrews University, Foster Henry
Published: May 2023

Problem. The traditional accounting pedagogy that served the industrial era effectively is losing its relevance. Not only do accounting graduates lack the kind of skills called for in an information age but the profession is no longer successful in attracting sufficiently large numbers of quality students. During the 1980s, professional and academic accountants as well as employers of accounting graduates began to voice their complaints about an accounting education model that had not experienced significant change in about a half century. In 1989 the Accounting Education Change Commission (AECC) was established to stimulate change and to act as a clearing house for innovative accounting pedagogy. The focus of the present study was the first course in accounting. Its purpose was to analyze (1) the impressions of students and faculty regarding the extent to which the course they experienced was congruent with AECC-based guidelines and (2) the relationship that those implemented AECC guidelines had on course retention and favorable student perceptions toward the accounting profession. Method. Student attitude was measured using Nelson's Accounting Attitude Scale. In addition, an instrument specifically designed for this study was used to obtain teacher and student observations regarding classroom activities that coincide with AECC-based guidelines. A total of 1,009 students and 22 teachers from both innovative and traditional accounting programs took part in the survey. Results. Significant differences in responses regarding the presence of AECC innovation-based guidelines were found between innovative and traditional accounting programs for both students and teachers. Innovative accounting programs were more successful in getting senior faculty involved in teaching the introductory course and experienced lower student drop-out rates than did those in programs classified as traditional. Conclusions. Changes are finally taking place in the accounting classroom but not to the extent that they produce favorable student attitudes toward either the course or the accounting profession. Academic accountants and administrators must be careful as change occurs that the curriculum does not move from one driven by the CPA exam to one driven entirely by the changing needs of the Big Six accounting firms.
Dropping out of High School Among African Americans in Benton Harbor, Michigan : a Study of its Economic Implications
Authors:   ,   Andrews University, Pottinger Dahlia
Published: May 2023

Problem This study examined the economic implications of dropping out of high school for African Americans in Benton Harbor, Michigan. Methods The methodology used in this study is a documentary one. Sources relating to the economic implications of dropping out o f high school among African Americans were studied. The United States 1990 Census o f Population, the National Center for Education Statistics, and local publications provided data for the research. Results Dropping out o f high school has definite economic implications for dropouts in Benton Harbor. The estimated number of African American dropouts as of 1990 was a total o f 3,578. Since one dropout loses in excess o f $200,000 over a lifetime (Catterall, 1986), the estimated income loss of Benton Harbor dropouts during their lifetime is $200,000 multiplied by 3,578. This is approximately $715.6 million. The community suffers economic loss because of the multiplier effect which conceptualizes the chain effect of money spent. There is no single factor that explains Benton Harbor students’ decision to drop out. Truancy, lack o f students’ interest, “a revolving superintendency syndrome,” very low MEAP scores, poverty, single parent-female headed families, and high number of welfare recipients, are related to the dropout problem. While students are dropping out, local businesses need workers with proficiencies in reading, writing, computation, and the ability to work with others to contribute to their economic success. Benton Harbor High School recognizes the economic implications o f linking education to work and attempts to prepare its students for the job market through hands on courses at the Benton Harbor Technical Center. The private and social costs o f dropping out are complex and difficult to estimate. Conclusion Dropping out of high school has economic implications for the Benton Harbor High School dropout, the community and the nation. It translates into loss of personal income over a lifetime, difficulty o f transition into the job market, unemployment, accessibility mainly to minimum wage jobs, a disparity in income and work-related benefits, a dependency on welfare, among others. Teaching economics to secondary students, with emphasis on staying in school and successfully graduating, can educate students regarding the financial benefits o f staying in school.
A Critical Study of Carl F. H. Henry's Portrayal of the Human Role in Revelation and Inspiration
Authors:   ,   Andrews University, Kharbteng Boxter
Published: May 2023

This dissertation investigated Carl F. H. Henry's portrayal of the human role in his doctrines of revelation and inspiration. The study queried whether his depiction of that role in revelation is harmonious or consistent with the one given in inspiration. This question arises from a consideration of Henry's own formulation of his doctrines of revelation, inspiration, and man. The thesis of this dissertation is that inasmuch as man has the innate ability to receive, understand, and impart revelation without divine help, he should likewise be expected to exercise that ability at the level of inspiration without detailed or comprehensive superintendence of the Holy Spirit. In the course of the investigation it was observed that man, during revelation, actively and independently uses his will, conscience, linguistic capacity, reasoning powers, memory, and verbal skills to receive, elucidate, or articulate revelation. Its nature is so adjusted to man that he does not need supernatural help to understand and communicate it. In fact his reasoning faculties can even discriminate between revelation and pseudo revelation. When it comes to inspiration, however, man is portrayed as one lacking the natural capacity to carry out the task, namely that of inscripturating revelation. This incompetency is brought about by his inherent sinfulness. To solve the predicament, God had to subject man to a long period of comprehensive training. That preparation, however, does not qualify him to execute independently his role in inspiration. Thus, the man that is depicted as active, independent, and naturally competent and ready for revelation is now portrayed at the level of inspiration as one who is naturally incompetent, unready, passive, and totally dependent upon supernatural help. This is despite the fact that man inerrantly receives, understands, remembers, and has the linguistic capacity to articulate revelation. In fact, he had to be given the mind of the Holy Spirit, and even guided in the choice of words. That is, Henry does not allow the competent operation of the writer's natural faculties in inspiration as he does in revelation. And neither does he admit the weaknesses and limitations of man as depicted in inspiration to have a bearing upon his reception and conveyance of revelation. In view of his insistence upon revelation's lucidity, its propositional form, man's linguistic capacity, the content identity between revelation and inspiration, as well as the identicalness of the human agent in the two events, Henry's divergent portrayal of human role within these phenomena betrays inconsistency. The study concluded by first pointing to Scripture's depiction of the human role in revelation and inspiration as being broader than that given by Henry. From that perspective, some suggestions were then recommended which hope to supply a degree of consistency in his portrayal of the human role in revelation and inspiration.
The Michael Figure in the Book of Daniel
Authors:   ,   Andrews University, Anderson Lewis
Published: May 2023

Problem. In the book of Daniel, The Michael figure, although mentioned only three times, occupies a prominent position in history and at the eschaton as the heavenly guardian prince of Israel. The Michael problem, although complex, may be understood as basically twofold: Who is Michael? What is Michael's function? In the first question, a basic issue is whether Michael is a prominent angel, or a divine, messianic being. Another issue in this same question is the extent to which Michael is to be identified with other OT beings, within or outside the book of Daniel, such as the Son of Man, Prince of the Host, and Angel of the Lord. In the second question, Michael's function in history in relation to the princes of Persia and Greece and his activity at the eschaton are considered. For example, is his function military, judicial, or both? Method. This was an exegetical study of the Michael passages in their historical setting with a comparison also of Michael with other OT figures. Conclusions. The conclusions reached are as follows: Michael is leader of the angelic hosts and of Israel, Daniel's people. He is Israel's patron, leader and. guardian, in history and at the eschaton. Michael appears to be more than an angel. With his own distinct identity, occupying a position of focus and attention more characteristic of the divine being and functioning as heavenly warrior who intervenes to save his people Israel, Michael is another depiction of God. Michael is identified with the Prince of the Host of Yahweh, a veiled depiction of God and the messianic, divine Son of Man. The Angel of the Lord is a precursor of Michael, functioning as God's visier and Israel's guardian, as does Michael in Daniel. Michael is God in His role as divine warrior, acting in behalf of His people Israel in salvation and judgment. The heavenly being who appeared in the fiery furnace is likely the divine Angel of the Lord, and is therefore probably Michael, Israel's guardian. Michael struggles in history with the demonic prince of Persia to prevent him from influencing the Persian king(s) to stop favoring Israel. Michael's eschatological functions are both judicial and military as he destroys the anti-God persecuting power, superintends the deliverance of Israel and the resurrection, and inaugurates the glorious new age.
РИНОК ФАРМАЦЕВТИЧНИХ ТОВАРІВ УКРАЇНИ: ПРОБЛЕМИ ТА ПЕРСПЕКТИВИ РОЗВИТКУ
Authors: Шимановська-Діанич Л. М. , Лозова О. В. , Юрко І. В.
Published: May 2023

Динамічний розвиток новітніх технологій породив безліч можливостей для фармацевтичних компаній у створенні нових товарів та ліків. Поряд із можливостями кожного дня у світовому масштабі виникають глобальні проблеми, які потребують від фармацевтичного ринку їх вирішення: старіння націй, погана екологія, пандемія, війна, депресивність глобалізованих міст та в результаті посилення хронічних хвороб у населення. Не стала виключенням у цих процесах і Україна. У статті розглянуто сучасний стан та перспективи розвитку фармацевтичного ринку України. Досліджено статистичну звітність, звіти міжнародних організацій та найбільших фармацевтичних компаній та зроблено висновки про подальший стан вітчизняного фармацевтичного ринку. Встановлено, що український фармацевтичний ринок у переважній більшості представлений аптеками та юридичними підприємствами, які намагаються розповсюджувати свою мережу у найбільших містах України. Визначено, що довоєнний період характеризувався динамічним зростанням кількості аптек та аптечних пунктів по всій країні, виходом найбільших фармацевтичних ринків на міжнародний рівень. Окреслено, що за кількістю жителів, які мають доступ до однієї аптеки, вітчизняні фармацевтичні підприємства мають найнижчий показник серед країн СНД та Європи, тому перспектив розвитку для аптек, аптечних пунктів та фармацевтичних товарів є більш ніж достатньо. Проаналізовано вплив війни на вітчизняний фармацевтичний ринок та відзначено, що за перші два місяці в результаті паніки та ажіотажу населення скупляло всі найпоширеніші ліки, не враховуючи їх необхідність та призначення. У результаті суттєвого зниження рівня доходів споживачів та окупації значної частини країни фармацевтичні компанії відчули на собі суттєве скорочення діяльності, зменшення доходів та прибутку. Більшість міжнародних та вітчизняних аналітиків прогнозують подальше скорочення обсягів роздрібного продажу фармацевтичних товарів, а тому більшість фармацевтичних компаній почали диференціювати свій бізнес та шукати нові альтернативні джерела збільшення доходів та реалізації фармацевтичних товарів на європейському ринку.
АНАЛІТИЧНІ ХАРАКТЕРИСТИКИ ТЕНДЕНЦІЙ ЗАЛУЧЕННЯ ІНОЗЕМНИХ ІНВЕСТИЦІЙ В ЕКОНОМІКУ УКРАЇНИ: МАКРОЕКОНОМІЧНИЙ, ГАЛУЗЕВИЙ ТА РЕГІОНАЛЬНИЙ АСПЕКТИ
Authors: Сарафин С. А. , Удалов П. Л. , Шингельський О. І. , Лаба С. В.
Published: May 2023

У статті визначено важливість та практичну цінність дослідження необхідності залучення країною іноземних інвестицій. Наведено перелік науковців, праці яких висвітлюють проблеми міжнародного руху іноземного капіталу та управління процесами інвестування в національній економіці. Проведено статистичний аналіз тенденцій залучення прямих іноземних інвестицій в економіку України за 2015-2021 роки. Визначено передумови посилення інвестиційної привабливості країни і їх пов’язано з тенденціями ВВП, середньомісячної заробітної плати, валового зовнішнього боргу, внутрішніх капітальних інвестицій, індексу інфляції. Проведено структурний аналіз географії прямого іноземного інвестування в економіку України. Зроблено висновок, що найбільшими інвесторами в Україну є Кіпр, Нідерланди, Швейцарія. Проаналізовано галузеву структуру прямих іноземних інвестицій в економіку України. Встановлено, що найбільші обсяги інвестиційного капіталу формуються в промисловості, фінансовій та страховій діяльності, інформації та телекомунікації. Надано аналітичні характеристики регіональним особливостям залучення іноземних інвестицій в економіку України та здійснено розподіл регіонів на групи лідерів та аутсайдерів. До лідерів залучення іноземних інвестицій віднесено Київську, Полтавську, Донецьку, Дніпропетровську, Львівську, Черкаську, Харківську області. Наголошено про критичний стан економіки України, що сформувався через гібридну та військову агресію сусідніх країн. Також основними причинами повільної інтеграції України у світовий фінансовий простір є інші проблеми – низький рівень реформування економіки, нерозвиненість внутрішнього фінансового ринку, невідповідність законодавства та інших норм міжнародним стандартам. Узагальнено обсяги залученого міжнародного капіталу Україною на перших етапах воєнного стану.
L'università come agente di innovazione sociale per i territori? Il caso del progetto di ricerca-azione AuroraLAB a Torino
Authors: Bragaglia Francesca , Rossignolo Cristiana
Published: May 2023

L'articolo affronta un tema ancora poco indagato in letteratura, ma sempre più importante nelle pratiche: il ruolo dell'università come "innovatore sociale". L'università è infatti oggi chiamata a svolgere un ruolo sociale, diretto e proattivo come at- tore urbano, e ad essere una leva importante per i territori più fragili e in difficoltà. Questa messa a servizio dell'università viene indagata attraverso alcune esperienze di ricerca-azione, in particolare attraverso il progetto AuroraLAB a Torino.
Siamo i nostri conflitti
Authors: Tacchio Silvana
Published: May 2023

Siamo i nostri conflitti in quanto l'essere figli, generati, è una condizione che ci rende uguali e unici. Lo spazio dell'umano è uno spazio precario con il quale si instaura un'incessante negoziazione intrapsichica, interpsichica e interistituzio-nale. È uno spazio che si presenta nel suo costituirsi come una narrazione appesa a eventi imprevedibili, incerti e complessi, di fronte ai quali l'individuo, se in preda ad ansie, disagi, paure, angosce, agisce difensivamente costituendosi come potenziale aggressore o vittima o isolandosi nell'indifferenza e nell'anaffettività pervasiva di un neutro altrove. La pandemia le guerre, le violenze, l'erosione del legame sociale, le disuguaglianze le catastrofi climatiche e ambientali hanno ac-cumunato l'essere umano nella vulnerabilità, di fronte alla quale necessita un risveglio emotivo capace di incontrare l'alterità nel comune destino e di attivare la cura, la speranza, la responsabilità, l'immaginazione per creare una nuova forma del mondo.
Diagnostica a distanza: connessione ospedale-territorio. Progetto sperimentale di tele-radiologia nell'Azienda Socio Sanitaria Ligure Asl2, Savona
Authors: Pratici Lorenzo , Zangrandi Antonello , Barisone Michela , Dotta Iuri , Damonte Prioli Marco , Cirone Monica
Published: May 2023

Il caso rappresenta un servizio innovativo offerto da ASL2 Savonese per conformazione del territorio e della popolazione della Provincia, dove si riscontra la concentrazione più alta di popolazione over 65. Il progetto di diagnostica a distanza prevede la realizzazione di un servizio di radiologia domiciliare, volto a incrementare la connessione ospedale-territorio in favore di tale fascia di popolazione.Con la Radiologia Domiciliare si intendono implementare servizi con procedure atte a effettuare esami di tipo radiologico al domicilio del paziente o in una struttura non ospedaliera o ambulatoriale.L'obiettivo del progetto consiste nel realizzare un Servizio Pubblico di Radiologia Domiciliare a beneficio di persone anziane, disabili o le cui condizioni di salute sconsigliano il trasporto presso una struttura ospedaliera.I risultati evidenziano l'impatto positivo del servizio sull'area savonese: il caso costituisce un esempio di implementazione di strumenti di telemedicina a domicilio, che possono essere utilizzati in maniera sostenibile, con costi contenuti a beneficio dell'intera comunità di riferimento dell'ASL2.
AUSL di Reggio Emilia: dalla cartella clinica informatizzata ospedaliera alla cartella clinica socio-sanitaria
Authors: Prenestini Anna , Marsilio Marta , Foracchia Marco , Guareschi Erika , Leoni Barbara , Masini Paola
Published: May 2023

Lo scopo del presente contributo è analizzare l'evoluzione delle progettualità di Information and Communication Technologies (ICT) dell'AUSL di Reggio Emilia, con particolare riferimento all'implementazione della cartella informatizzata. Sin dai primi anni Duemila, le preesistenti Azienda Territoriale e Azienda Ospedaliera di Reggio Emilia hanno sviluppato una cultura e una strategia ICT integrate, basate su tre punti cardine: 1) allineamento alla strategia aziendale; 2) approccio di project management; 3) misurazione dei risultati e del valore prodotto dall'implementazione delle innovazioni ICT. È stato costituito il Comitato di Pianificazione Strategica IT con compiti di definizione delle strategie triennali ICT e di monitoraggio dei risultati dei progetti. Tra questi ultimi, uno dei più rilevanti è stato il progetto di cartella clinica informatizzata "Matilde", attivato inizialmente sull'Azienda Ospedaliera nel 2013 ed esteso, dopo la fusione aziendale del 2017, sugli altri 5 ospedali. Tale progetto, concluso nel 2021, si è posto come obiettivo la completa gestione digitale sia della componente documentale della cartella sia di ogni operatività clinica, creando uno strumento unico di gestione del percorso clinico ospedaliero. Durante la pandemia da Covid-19, l'utilizzo della cartella clinica è stato esteso alle cliniche private e alle strutture territoriali pubbliche e private accreditate. Oggi, l'AUSL di Reggio Emilia sta intraprendendo un percorso di implementazione di una cartella clinica, sociale e socio-sanitaria, condivisa da tutti i soggetti pubblici e privati della provincia.
I primi 1000 giorni delle famiglie: l'esperienza de La Casa della Genitorialità
Authors: Bottalico Francesca , Colonna Valentina , Teresa Di Ruvo Simona , Perillo Rossella
Published: May 2023

La Casa della Genitorialità e un progetto innovativo di sostegno e accompagnamento per neogenitori. I primi 1000 giorni di vita costituiscono una finestra temporale decisiva per costruire le basi per un adeguato sviluppo fisico e psichico del bambino e attivare tempestivamente interventi di prevenzione e protezione in situazioni di fragilita e di pregiudizio, per tutelare e migliorare la qualita di vita del bambino con effetti duraturi anche in eta adulta. Una famiglia adottiva, al pari di una famiglia biologica, ha necessita di 1000 giorni (e oltre), indipendentemente dall'eta anagrafica del bambino, per settare e declinare uno spazio di vita funzionale alla crescita del figlio e, al pari di un bambino appena venuto al mondo, un bambino gia nato e rinato all'interno di una nuova famiglia, non biologica ma adottiva, ha bisogno di 1000 giorni (e oltre) per poter destrutturare e ristrutturare la sua vita e i suoi legami.
Nuove risorse dell'accoglienza: la late adoption. Uno studio esplorativo presso il Tribunale per i minorenni di Bari
Authors: Costantini Alessandro , Corriero Michele , Vurchio Maria
Published: May 2023

Questo studio, realizzato presso il Tribunale per i minorenni di Bari dall'equipe adozioni, e volto a descrivere le caratteristiche di minori adottati tardivamente e delle famiglie accoglienti. Lo studio si propone con approccio descrittivo, di evidenziare come l'adozione tardiva, pur caratterizzandosi potenzialmente da molteplici fattori di rischio, sia comunque una esperienza realizzabile e come tale perseguibile, anche in eta preadolescenziale e adolescenziale. Piu specificamente, trattandosi di casi di successo adottivo, attraverso un'analisi delle caratteristiche dei minori e delle famiglie accoglienti, si intende evidenziare i fattori protettivi e criticita di questo tipo di accoglienza.
La persona alla ricerca delle proprie origini: il dialogo tra le istituzioni e le buone pratiche condivise
Authors: Montaldi Alida
Published: May 2023

Questo contributo raccoglie la riflessione sull'esperienza realizzata nel Tribunale per i minorenni di Roma nel Collegio costituito per le domande presentate ai sensi dell'art. 28 della legge n. 184/1983. In questa prospettiva viene esaminato il quadro normativo di riferimento e l'elaborazione più recente della giurisprudenza europea e di legittimità nazionale formatasi nell'attuazione del diritto a conoscere le origini, continuando a oggi la carenza di una puntuale normazione su questo tema. Ulteriori osservazioni riguardando le procedure sperimentate in questa esperienza e i punti che possono rappresentare prassi virtuose.
Tribunale per i minorenni
Authors: della Redazione A cura
Published: May 2023

Tribunale per i minorenni di Genova, 27 gennaio 2020

Tribunale per i minorenni di Genova, 24 maggio 2021

Tribunale per i minorenni di Genova, 4 ottobre 2021

Tribunale per i minorenni di Genova, 28 marzo 2022

Tribunale per i minorenni di Genova, 11 aprile 2022

Tribunale per i minorenni di Roma, 18 settembre 2018

Tribunale per i minorenni di Roma, 12 ottobre 2020

Tribunale per i minorenni di Roma, 30 marzo 2022

Tribunale per i minorenni di Roma, 13 giugno 2022
Peripheral blood infl ammatory markers as signals of mental disorders in a sample of elderly people
Authors: D’Auria Ciro
Published: May 2023

The physiological epiphenomena and the concurrent and altered emotional and cognitive states exhibit themselves in the brain and peripherally as well. Depres- sion also carries allostatic changes related to inflammation and hormonal imba- lances, the same applies to anxiety and cognitive impairments. After examining alterations in scientific literature, we proceed with a cross-sectional study consi- dering a sample made of a group of elderly people from Northern Italy, in order to highlight potentially altered hematic levels of inflammatory markers in the serum in combination with depression, anxiety, and cognitive impairment me- asurements. As far as we know, inflammatory markers such as PLR and MLR have never been studied for this purpose in the elderly. Results exhibit differen- ces in the PLR between people with and without depression, differences in the NLR, PLR, and MLR between people with anxiety, and a predictive value in the WBC parameter, PLR, and TSH related to the cognitive state. The data suggest that, in given circumstances, inflammatory markers taken from plasma could help diagnose mental disorders and develop targeted treatments.
Inteligencia Artificial y Juegos de Tablero: Desde el Turco hasta AlphaZero
Authors:   Universidad Autónoma del Estado de México, Valencia Ivan Francisco , Valdovinos Rosas Rosa María ,   Universidad Autónoma del Estado de México, Marcial Romero J. Raymundo ,   Universidad Autónoma del Estado de México, Eleuterio Roberto Alejo ,   Tecnológico Nacional de México/IT Toluca, México, México
Published: May 2023

El presente artículo tiene como objetivo mostrar la evolución del desarrollo de agentes inteligentes capaces de jugar juegos de tablero. Se muestra una breve revisión histórica de los agentes que se han desarrollado para diversos juegos y se describe el agente AlphaZero, creado por DeepMind, el cual hoy en día es el agente más avanzado en esta área es capaz de vencer a campeones humanos en el juego de Go, el cual se considera el juego de tablero más complejo que existe, incluso más que el ajedrez. De igual manera, se da una discusión sobre el paso natural que seguirán los agentes jugadores debido al éxito de AlphaZero y al surgimiento del paradigma de General Game Playing, el cual busca la creación de agentes capaces de jugar cualquier juego de tablero sin ninguna intervención humana.
Musicians During COVID-19: Collaboration, Connection and Cacophony
Authors: Moffatt Ken
Published: May 2023

With music communities cut off from one another physically due to COVID-19, collaboration and creation has greatly shifted. The pandemic has restricted what avenues are possible for sharing work, and technology has allowed us to continue to connect, create and use our voices during social isolation. At the same time, technology continues to affect the economic well-being of musicians at a time of increasing precariousness and mediates how we relate to one another. Through a series of live streamed performances and discussions, six musicians and educators  explore the complexities of creating music and culture intertwined with technology. 
The Association between Adverse Pregnancy Outcomes and Laboratory Measures as Risk for Cardiovascular Disorders
Authors: Haneen Hussein Farhood  , Manal Khalid Abdulridha  , Hameedah Hadi
Published: May 2023

Background; Due to the complicated etiology of cardiovascular illnesses, a thorough risk assessment is necessary for screening reasons. Many published studies relate the pregnancy complications and future cardiovascular disease (CVD) risk. Objective; Investigate the association between risk factors of the laboratory measures and adverse pregnancy outcomes (APOs) with level of cardiovascular disorders risk. Methods; Adult women were enrolled in a cross-sectional study, and they were divided into 2 groups according to whether they had a history of adverse pregnancy outcomes or not. Laboratory and clinical measurements were carried out, and The CVD risk was calculated according to Framingham risk score. Results; All women enrolled were over 40 years age, mostly obese, had predominantly A+ve and O+ve blood group phenotypes. As compared to the low risk category, women with a positive history of pregnancy-induced hypertension and preeclampsia were 7.5 times more likely to be in the intermediate group while those with a positive history of stillbirth were 17.2 times more likely to be in the high-risk group. Conclusion; With reference to the low risk category, a positive history of pregnancy-induced hypertension and preeclampsia was predictor for intermediate CVD risk, while a positive history of stillbirth was predictor for high CVD risk.
Synthesis, Characterization, ADME Study and Antimicrobial Evaluation of New 1,2,3-triazole Derivatives of 2-phenyl benzimidazole.
Authors: Asmaa Adnan Abdulnabi  , Karima Fadhil Ali  , Basma M.Abd Razik
Published: May 2023

Novel 2-amino benzimidazole derivatives containing amide, azide and 1,2,3-triazole moieties have been synthesized. Compound 3 was synthesized by reaction of o-phenylenediamine with p-aminobenzoic acid. Compound 3 was converted into amide by treatment with chloroacetyl chloride to get compound 4. Compound 4 and sodium azide were combined to create compound which has an azide group. Compound 5 was converted into 1,2,3-triazole derivatives by treatment with acetylene derivatives. FTIR, 1H-NMR, and Mass spectra have been used to confirm the chemical structures of various substances. By using a technique called well diffusion agar, the final products were examined in vitro to predict activity against two kinds of gram-positive bacteria and two kinds of gram-negative bacteria as well as the antifungal activity against Candida albicans fungus. All the final products exhibited moderate to potent activity compared to Trimethoprim and Fluconazole as reference antibacterial and antifungal drugs respectively. Swiss ADME was also used to undertake ADME tests to determine the bioavailability, drug-likeness and topological polar surface area of the synthesized molecule. The results showed that every chemical tested was absorbed orally and followed the Lipinski rule.
Tax policies for high-tech companies and tax avoidance in China
Authors: Yoon Sung Man , Jiang En Lu , Cui Ying
Published: May 2023

The New Enterprise Income Tax Act was passed by the Chinese government in 2008, which reduced the tax rate from 33% to 25% and applied a tax rate of 15% to high-tech businesses as a preferential tax policy. This shows that high-tech businesses are taxed differently from other businesses. The study aims to analyse how the Chinese government's ownership affects the tax avoidance of high-tech enterprises.  The analysis's findings are listed below. First off, high-tech corporations engaged in more tax avoidance than other businesses did before to the 2008 tax rate cut. This means that high-tech companies, with large effect of the tax rate cut, have more incentives to minimize their tax burden in the year immediately preceding the tax rate cut compared to general companies. Second, the higher the Chinese government's ownership ratio, the lower the level of tax avoidance. Third, the higher the ownership is, the higher the tax avoidance behaviour becomes in the year just before the tax rate cut. This study provides policy implications pertaining to the tax avoidance behaviour of companies in the case of tax rate cuts and experimental situations in which a differential tax exists.
Influence brand awareness and brand association on brand equity: Mediation of trust and brand loyalty in Kentucky Fried Chicken in East Java, Indonesia
Authors: Sugiarti  , Surachman  , Rohman Fathur , Wijayanti Risna
Published: May 2023

The aim of this study is to empirically prove how trust and loyalty mediate the effect of brand awareness and association on the brand equity of Kentucky Fried Chicken in East Java. The research sample consists of 200 customers, and data analysis was conducted using Structural Equation Modeling. The results of the study show that brand awareness and associations have an effect on trust, loyalty, and brand equity. Trust and brand loyalty are found to mediate the influence of brand awareness and associations on brand equity. These findings contribute to the development of consumer brand relationship theory, which suggests that an emotional connection between fast food brands and customers can lead to strong brand equity. In the case of KFC, brand equity is strengthened through brand awareness and association, which in turn create trust and brand loyalty. The implications of these results for KFC management in East Java are that they should focus on increasing the popularity of the KFC brand through content marketing, sponsoring various activities, and using endorsers to ensure that customers always remember KFC as a fast-food brand. KFC outlets in East Java consistently maintain the quality of their products and always maintain good relationships with customers, so that customers are willing to recommend KFC to others.
Концепція несподіваного поєднання технологій і застосування
Authors: Семон Б. Й. , Дихановський В. М.
Published: May 2023

Запропоновано нову послідовність дій зі створення нових засобів озброєння на основі концепції несподіваного поєднання технологій і застосування. Вона передбачає використання громадянами передових комерційних технологій для створення нових бойових спроможностей новими креативними способами. Одночасно створюється новий засіб озброєння і розробляється сценарій його бойового застосування, що дає змогу пришвидшити створення і розвиток спроможностей. Основним фактором досягнення переваги над противником є «генерація ідей».