bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding the impact of Bi stoichiometry towards optimised BiFeO3 photocathodes: structure, morphology, defects and ferroelectricity
Authors: Yuan Haozhen , Pal Subhajit , Forrester Chloe , He Qinrong , Briscoe Joe
Published: June 2024

Accurate control and measurement of stoichiometry of BiFeO3 is achieved and linked to photoelectrochemical performance showing slight Bi excess leads to maximum photocurrent. This can be further enhanced through ferroelectric poling.
Correction: UHPLC-MS/MS combined with microdialysis for simultaneous determination of nicotine and neurotransmitter metabolites in the rat hippocampal brain region: application to pharmacokinetic and pharmacodynamic study
Authors: Zhu Mingyu , Cui Lili , Liu Guanglin , Yu Pengpeng , Hu Qingyuan , Chen Huan , Hou Hongwei
Published: June 2024

Correction for ‘UHPLC-MS/MS combined with microdialysis for simultaneous determination of nicotine and neurotransmitter metabolites in the rat hippocampal brain region: application to pharmacokinetic and pharmacodynamic study’ by Mingyu Zhu et al., Anal. Methods, 2024, https://doi.org/10.1039/d4ay00522h.
Synthesis and soft crystal structure-induced broad emission of (NH3C6H12NH3)InBr5·2H2O
Authors: Biswas Shuva , Mandal Arnab , Swain Diptikanta , Biswas Kanishka
Published: June 2024

We report a simple synthesis of a new lead-free zero-dimensional (0D) hybrid halide compound, (5P1)InBr5·2H2O [(5P1) = NH3C6H12NH3], which shows dual emission coming from band-to-band and STE state.
Design of 3D flower-like NiWO4/WO3 heterostructures with excellent trimethylamine sensing performance
Authors: Meng Dan , He Chun , Zhang Lei , Zhang Yue , Li Ruixiang , Tao Kai , San Xiaoguang
Published: June 2024

3D flower-like NiWO4/WO3 heterostructures were fabricated, which exhibit high sensitivity and a low detection limit to TMA, arising from synergistic effects and structural characteristics.
Electronic structures of three anchors of triphenylamine on a p-type nickel oxide(100) surface: density functional theory with periodic models
Authors: Kontkanen Outi V. , Hukka Terttu I. , Rantala Tapio T.
Published: June 2024

Pyridinyl is a promising anchoring group on the NiO(100) surface, as it can transfer charges and does not create trap states.
Magnetic resonance imaging: an innovative approach to observe rare metal extraction using ionic liquid
Authors: Dorai Arunkumar , Panigrahi Mrutyunjay , Iwai Yoshiki , Hellar Nithya , Kawamura Junichi
Published: June 2024

The extraction mechanism of rare metals through ionic liquids is evaluated using NMR spectroscopy. 1H MRI is used to indirectly visualize neodymium extraction.
Synthesis of ethylene copolymers with 2-allylphenol by using half-titanocene catalysts containing SiEt3-, SiiPr3-substituted phenoxide ligands, Cp*TiCl2(O-2,6-iPr2-4-SiR3-C6H2) (R = Et, iPr)
Authors: Jiang Youshu , Shimoyama Daisuke , Gao Jiahao , Nomura Kotohiro
Published: June 2024

Efficient synthesis of ethylene copolymers with 2-allylphenol has been achieved by using the Cp*TiCl2(O-2,6-iPr2-SiEt3-C6H2)–MAO catalyst system.
A magnesium phosphonate metal–organic framework showing excellent performance for lead(ii) sensing and removal from aqueous solutions
Authors: Zhou Qiankun , Chen Ming , An Yubo , Tang Xiaoyan , Matsuda Ryotaro , Ma Yunsheng
Published: June 2024

Mg-MOF shows high stability, assertive luminescence behavior, and the ability to sense Pb2+ ions even in the presence of other metal ions. Interestingly, the Mg-MOF shows excellent performance for Pb2+ removal with a high uptake capacity.
Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage
Authors: Ivarsson John , Bennett Abby , Ferrara Francesca , Strauch Renee , Vallase Andrea , Iorizzo Massimo , Pecorelli Alessandra , Lila Mary Ann , Valacchi Giuseppe
Published: June 2024

As the first line of defense, the skin is equipped with various physiological mechanisms positioned to prevent incoming oxidative damage from numerous environmental insults.
Emerging applications of deep eutectic solvents in the preparation and functionalization of biomass-derived carbonaceous materials: challenges and prospects
Authors: Shen Yiyi , Zhou Haiqin , He Xiaotong , Shen Feng , Xu Zhixiang , Yang Bo , Kong Lingzhao , Dai Lichun
Published: June 2024

Deep eutectic solvents can be used as the pretreatment solvents, carbon precursors, soft templates, carbonization media, and post-modification agents for the preparation and functionalization of biomass-derived carbonaceous materials.
New wide band gap dithieno[3′,2′:5,6;2′′,3′′:7,8]naphtho[2,3-d]imidazole-9(10H)-one-containing polymers and ternary composites with fullerene and non-fullerene acceptors: mobility of charge carriers
Authors: Pozin Sergey I. , Aleksandrov Alexey E. , Arutinov Nikita E. , Kalinkin Dmitri P. , Godovsky Dmitri Y. , Keshtov Mukhamed L. , Tameev Alexey R.
Published: June 2024

Balanced mobility of holes and electrons in a ternary composite.
A hierarchical V2O3@C hollow microsphere cathode with high performance for zinc-ion batteries
Authors: Zhang Meng , Ma Yongpeng , Dong Yutao , Han Lifeng , Sui Xueying , Guo Dongjie , Liang Xinxin , Ding Junwei , Zhao Jianbo
Published: June 2024

Novel hierarchical V2O3@C hollow microspheres were prepared using a hydrothermal-carbonization strategy and the obtained Zn3(OH)2(V2O7)·(H2O)2@C by electrochemical conversion delivered high capacity, excellent rate performance, and long cycle stability.
Triphenylene trimeric discotic liquid crystals: synthesis, columnar mesophase and photophysical properties
Authors: Tao Lei , Xie Yang , Zhao Ke-Xiao , Hu Ping , Wang Bi-Qin , Zhao Ke-Qing , Bai Xiao-Yan
Published: June 2024

Triphenylene trimeric discotic liquid crystals showed oblique columnar mesophases over a broad temperature range and blue photo-induced luminescence.
Dinuclear gold(i) complexes with pyrimidine- and m-carborane-based bisphosphine ligands: synthesis, structure, photoluminescence and cytotoxicity against malignant pleural mesothelioma
Authors: Bardina Elena E. , Matnurov Egor M. , Bakaev Ivan V. , Rakhmanova Mariana I. , Davydova Maria P. , Artem’ev Alexander V. , Babak Maria V. , Gushchin Artem L.
Published: June 2024

Novel luminescent and anticancer dinuclear Au(i) complexes with bisphosphine ligands have been synthesized and studied.
Correction: Potentiality of zinc phosphate@hydroxyapatite/β-cyclodextrin composites for carrying cisplatin: loading, release and cytotoxicity
Authors: Bin Jumah May N. , Al Othman Sarah I. , Alomari Awatif Abdulaziz , Allam Ahmed A. , Abukhadra Mostafa R.
Published: June 2024

Correction for ‘Potentiality of zinc phosphate@hydroxyapatite/β-cyclodextrin composites for carrying cisplatin: loading, release and cytotoxicity’ by May N. Bin Jumah et al., New J. Chem., 2024, https://doi.org/10.1039/d4nj01547a.
Highly efficient iron-catalyzed conjugate reduction of α,β-unsaturated ketones with polymethylhydrosiloxane
Authors: Wang Hang , Chen Libo , Chen Yushuang , Zhang Yulong
Published: June 2024

We introduce a novel method for the selective reduction of α,β-unsaturated ketones, employing a cheap and air-stable silane (PMHS) with catalytic iron salt. This system achieves excellent results on a broad substrate scope under mild conditions.
Electrochemically promoted thio-Michael addition of N-substituted maleimides to thiols in an aqueous medium
Authors: Wu Run , Xu Haojian , Zhou Haiping , Yu Pingbing , Wen Zhaoyue , Chen Wei
Published: June 2024

A stable and practical electrochemical method was developed to promote the thio-Michael addition of N-substituted maleimides to various thiols in an aqueous medium.
Investigation of the effects of irradiation and aging on the tribological behavior of ultra-high molecular weight polyethylene/graphene oxide composites under water lubrication
Authors: Huang Guodong , Lv Weiwen , Zhu Yaowu , Zhang Zhigang , Jin Xuxing , Liu Haowu , Zhang Tao , Yang Fei , Lu Min , Zhao Yongwu
Published: June 2024

The friction coefficient versus time curve of PE-UHMW and PE-UHMW/GO composite materials treated differently under water lubrication.
Modifications of the charge–discharge behaviour of Fe2(MoO4)3 in all-solid-state lithium-ion batteries
Authors: Kimura Yuta , Kobayashi Shintaro , Kawaguchi Shogo , Ohara Koji , Suzuki Yasuhiro , Nakamura Takashi , Iriyama Yasutoshi , Amezawa Koji
Published: June 2024

Operando X-ray diffraction measurements revealed that Fe2(MO4)3 electrode thin films on solid electrolytes possess an expanded solid-solution reaction region and narrower two-phase reaction region compared to those in liquid electrolytes.
Autonomous closed-loop photochemical reaction optimization for the synthesis of various angiotensin II receptor blocker molecules
Authors: Aand Dnyaneshwar , Rana Abhilash , Mottafegh Amirreza , Kim Dong Pyo , Singh Ajay K.
Published: June 2024

Optimization is gaining huge attention in industries like pharmaceuticals, fine chemicals, and petrochemicals to maximize reaction yield, minimize waste, and improve process efficiency.
A Λ-Ir(iii)-phenylquinazolinone complex enhances ferroptosis by selectively inhibiting metallothionein-1
Authors: Zhu Lu , Wang Xingyun , Tian Tian , Chen Yanyan , Du Wenjing , Wei Wei , Zhao Jing , Guo Zijian , Wang Xiuxiu
Published: June 2024

A Λ-Ir(iii)-phenylquinazolinone complex (Λ-IrPPQ) which sensitized cancer cells to ferroptosis by inducing more significant inhibition of MT1 and enhanced inactivation of FSP1 was obtained via chiral programming.
Hydrogel–tissue adhesion by particle bridging: sensitivity to interfacial wetting and tissue composition
Authors: Michel Raphaël , Corté Laurent
Published: June 2024

Peeling experiments reveal that particle bridging takes place when liquid is drained from the hydrogel–tissue interface and that detachment processes depend on local tissue composition.
Correction: Flax fibre reinforced alginate poloxamer hydrogel: assessment of mechanical and 4D printing potential
Authors: de Kergariou Charles , Day Graham J. , Perriman Adam W. , Armstrong James P. K. , Scarpa Fabrizio
Published: June 2024

Correction for ‘Flax fibre reinforced alginate poloxamer hydrogel: assessment of mechanical and 4D printing potential’ by Charles de Kergariou et al., Soft Matter, 2024, 20, 4021–4034, https://doi.org/10.1039/D4SM00135D.
Research progress on the preparation of transition metal-modified zeolite catalysts and their catalytic performance for the purification of engine exhausts
Authors: Chen Xinyu , Zhou Shengran , Zhang Xinyu , Chen Siyuan , Wang Lanyi , Zhang Chunlei , Gao Siyu , Yu Di , Fan Xiaoqiang , Cheng Ying , Zhang Yinguang , Yu Xuehua , Zhao Zhen
Published: June 2024

This article focuses on the preparation of transition metal-modified zeolite catalysts and their catalytic performance for the purification of engine exhausts.
Anomalous thermal transport of vertically stacked PtSe2 thin films with interface formation
Authors: Cho Jung-Min , Lee Won-Yong , Tonni Farjana Ferdous , Kim Min-Jeong , Kim Yun-Ho , Kwon Hyeok Jun , Choi Jae-Won , Zebarjadi Mona , Park No-Won , Das Sree Sourav , Kim Gil-Sung , Lee Sang-Kwon
Published: June 2024

Our study of PtSe2/PtSe2 homostructures has revealed that the interface can independently regulate factors influencing the thermoelectric figure of merit. This discovery has implications for the development of high-performance thermoelectric devices.
A mechanical–optical coupling design on solar and thermal radiation modulation for thermoregulation
Authors: Guo Na , Shi Changmin , Sheldon Brian W. , Yan Hongjie , Chen Meijie
Published: June 2024

A multi-layer structure was designed to achieve mechanical deformation-induced solar and thermal radiation synchronous modulation, which can achieve dynamic thermoregulation and save the total energy consumption in buildings.
Recent research progress on tumour-specific responsive hydrogels
Authors: Zhou Xuan-Yi , Wang Chen-Kai , Shen Ze-Fan , Wang Yi-Fan , Li Yu-Hang , Hu Yu-Ning , Zhang Pu , Zhang Qi
Published: June 2024

Exploring novel advancements in hydrogels tailored for tumor-specific responsiveness, promising breakthroughs in cancer treatment.
Galectin-3 inhibition alleviated LPS-induced periodontal inflammation in gingival fibroblasts and experimental periodontitis mice
Authors: Wenjing Song , Mengmeng Liu , Lingling Shang , Tian Ding , Wenyan Kang , Shaohua Ge
Published: June 2024

Objectives: Clinical studies have confirmed that galectin-3 (Gal-3) levels are significantly elevated in periodontitis patients. The present study aimed to explore the effects of Gal-3 inhibition on periodontal inflammation in vitro and in vivo. Methods: Human gingival fibroblasts (HGFs) with or without Gal-3 knockdown were stimulated by lipopolysaccharide (LPS), and a ligation-induced mouse periodontitis model treated with a Gal-3 inhibitor was established. Hematoxylin–eosin (H&E) and immunohistochemistry (IHC) staining were used to evaluate Gal-3 levels in gingival tissues. Quantitative real-time polymerase chain reaction (qRT-PCR) and enzyme-linked immunosorbent assay (ELISA) were used to detect Gal-3, interleukin (IL)-6, IL-8, and C-C motif ligand 2 (CCL2) expression. Immunofluorescence and western blotting were used to detect NF-κB and ERK signaling pathway activation. Micro-computed tomography was used to analyse the degree of bone loss. Results: Gal-3 was significantly up-regulated in inflamed gingival tissues and LPS-induced HGFs. Gal-3 knockdown markedly decreased LPS-induced IL-6, IL-8, and CCL2 expression and blocked NF-κB and ERK signaling pathway activation in HGFs. In the mouse periodontitis model, Gal-3 inhibition significantly alleviated IL-1β and IL-6 infiltration in gingival tissue and mitigated periodontal bone loss. Conclusions: Gal-3 inhibition notably alleviated periodontal inflammation partly through blocking NF-κB and ERK signaling pathway activation.
IGFBP7 promotes endothelial cell repair in the recovery phase of acute lung injury
Authors: He Rui , Feng Bo , Zhang Yuezhou , Li Yuqing , Wang Daoxing , Yu Linchao
Published: June 2024

IGFBP7 has been found to play an important role in inflammatory diseases, such as acute lung injury (ALI). However, the role of IGFBP7 in different stages of inflammation remains unclear. Transcriptome sequencing was used to identify the regulatory genes of IGFBP7, and endothelial IGFBP7 expression was knocked down using Aplnr-Dre mice to evaluate the endothelial proliferation capacity. The expression of proliferation-related genes was detected by Western blotting and RT-PCR assays. In the present study, we found that knockdown of IGFBP7 in endothelial cells significantly decreases the expression of endothelial cell proliferation-related genes and cell number in the recovery phase but not in the acute phase of ALI. Mechanistically, using bulk-RNA sequencing and CO-IP, we found that IGFBP7 promotes phosphorylation of FOS and subsequently up-regulates YAP1 molecules, thereby promoting endothelial cell proliferation. This study indicated that IGFBP7 has diverse roles in different stages of ALI, which extends the understanding of IGFBP7 in different stages of ALI and suggests that IGFBP7 as a potential therapeutic target in ALI needs to take into account the period specificity of ALI.
The ESO-VLT MIKiS survey reloaded: The internal kinematics of the core of M75
Authors: Leanza Silvia , Pallanca Cristina , Ferraro Francesco R. , Lanzoni Barbara , Vesperini Enrico , Cadelano Mario , Origlia Livia , Fanelli Cristiano , Dalessandro Emanuele , Valenti Elena
Published: June 2024

We present the results of a study aimed at characterizing the kinematics of the inner regions of the halo globular cluster M75 (NGC 6864) based on data acquired as part of the ESO-VLT Multi-Instrument Kinematic Survey (MIKiS) of Galactic globular clusters. Our analysis includes the first determination of the line-of-sight velocity dispersion profile in the core region of M75. By using MUSE/NFM observations, we obtained a sample of ∼1900 radial velocity measurements from individual stars located within 16″ from the cluster center (corresponding to about r < 3 rc, where rc is the estimated core radius of the system). After an appropriate selection of the most accurate velocity measures, we determined the innermost portion of the velocity dispersion profile, finding that it is characterized by a constant behavior and a central velocity dispersion of σ0 ∼ 9 km s−1. The simultaneous King model fitting to the projected velocity dispersion and density profiles allowed us to check and update previous determinations of the main structural parameters of the system. We also detected a mild hint of rotation in the central ∼7″ from the center, with an amplitude of just ∼1.0 km s−1 and a rotation axis position angle of PA0 = 174°. Intriguingly, the position angle is consistent with that previously quoted for the suspected rotation signal in the outer region of the cluster. Taking advantage of the high quality of the photometric catalog used for the analysis of the MUSE spectra, we also provide updated estimates of the cluster distance, age, and reddening.
Exploring the nature of dark matter with the extreme galaxy AGC 114905
Authors: Mancera Piña Pavel E. , Golini Giulia , Trujillo Ignacio , Montes Mireia
Published: June 2024

AGC 114905 is a dwarf gas-rich ultra-diffuse galaxy seemingly in tension with the cold dark matter (CDM) model. Specifically, the galaxy appears to have an extremely low-density halo and a high baryon fraction, while CDM predicts dwarfs to have very dense and dominant dark haloes. The alleged tension relies on the galaxy’s rotation curve decomposition, which depends heavily on its inclination. This inclination, estimated from the gas (neutral atomic hydrogen, H I) morphology, remains somewhat uncertain. We present unmatched ultra-deep optical imaging of AGC 114905 reaching surface brightness limits μr, lim ≈ 32 mag/arcsec2 (3σ; 10 arcsec × 10 arcsec) obtained with the 10.4 m Gran Telescopio Canarias. With the new imaging, we characterise the galaxy’s optical morphology, surface brightness, colours, and stellar mass profiles in great detail. The stellar disc has a similar extent to the H I disc, presents spiral arms-like features, and shows a well-defined edge. Stars and gas have a similar morphology, and crucially, we find an inclination of 31 ± 2°, in agreement with the previous determinations. We revisit the rotation curve decomposition of the galaxy, and we explore different mass models in the context of CDM, self-interacting dark matter (SIDM), fuzzy dark matter (FDM) or Modified Newtonian dynamics (MOND). We find that the last does not fit the circular speed of the galaxy, while CDM only does so with dark halo parameters rarely seen in cosmological simulations. Within the uncertainties, SIDM and FDM remain feasible candidates to explain the observed kinematics of AGC 114905.
Assessment of food security status of Bajo fishing households in Kabawo Subdistrict, Southeast Sulawesi
Authors: Erfin Erfin , Saediman Haji , Batoa Hartina , Yunus Lukman , Alwi La Ode , Alam Syamsul , Mboe Ilham Saediman
Published: June 2024

Coastal communities can be particularly vulnerable to food insecurity due to a combination of factors related to their geographical location, socio-economic conditions, and environmental challenges. This research aimed to evaluate the level of food security in Bajo fishermen’s households. The study was undertaken in Kawite-wite Village, Kabawo Subdistrict, Muna Regency in Southeast Sulawesi. There were 161 Bajo fishing households living in the village, of which 64 households were selected as respondents. The food security status was assessed using the US Department of Agriculture’s household food security survey module. Study results indicated that 6.25% of households were in marginal food security status, 18.75% were in very low food security status, 65.54% were in low food security status, and 9.38% were in high food security status. If only grouped into two categories, 84.38% of households were food insecure, while the remaining 15.63%were food secure. The findings showed that most Bajo households were food insecure. Households employed two strategies to overcome food shortages, namely those pertaining to food and those pertaining to income and expenditure. The government and all stakeholders need to improve the food security status of Bajo fishing households.
Economic analysis of flying fish roe harvesting: The case of Wakatobi fishers operating in the Aru Islands, Maluku Province
Authors: Saediman Haji , Yana Wa Ode , Hidrawati Hidrawati , Yunus Lukman , Alwi La Ode , Alam Syamsu , Mboe Ilham Saediman
Published: June 2024

The substantial market value of flying fish roe on the international stage has catalyzed excessive harvesting activities across its fishing grounds around Aru Islands, Maluku Province and has attracted fishers from various places to engage in the fisheries. This study aims to outline the income dynamics of flying fish roe harvesters from Wakatobi District who participated in the fisheries. Data were collected between December 2019 and April 2020 in Binongko Subdistrict, Wakatobi District, Southeast Sulawesi. Analysis was carried out to calculate the operational cost and returns gained by the harvesters. Ten fishers, each represented one of ten different harvesting groups, were selected as respondents. The study found that each harvesting group undertook an average of five harvesting trips per season. The cumulative income per fishing boat amounted to IDR 690,375,110 per season (or a six month period). The income distribution was based on a profit-sharing scheme, with 2/5 shares going to the boat owner and 3/5 shares going to the combined fishers (the captain and crews). Consequently, a fisher can make IDR 59,175,009 on average per season. The study provides a fundamental information for developing policies in promoting sustainability of the fisheries in the economic perspective.
Phytochemical Study and Antioxidant Potential of Three Leaf Extracts of Cannabis sativa L from the Al-Hoceima Region, Morocco
Authors: Ahidar Naoufal , Labhar Amina , Benamari Omar , Ahari Mhamed , Salhi Amin , Elyoussfi Abdellah , Amhamdi Hassan
Published: June 2024

Within Morocco's efforts to increase the value of cannabis, we investigated the 'Beldeya' cannabis sativa L plant, which is produced in the Ketama area of northern Morocco. In this investigation, we performed phytochemical screening and quantitative analyses of ethanol, chloroform, and hexane extracts from cannabis leaves. Additionally, we explored the antioxidant potential using two extraction methods: Maceration and Soxhlet extraction. According to the results of the phytochemical screening, most metabolites were present in the extracts, except for alkaloids and anthraquinones which were not detected in any of the extracts. We employed standard methods for the quantitative measurement of total phenol (TPC) and flavonoid content (TFC), and the results showed that the TPC and TFC were abundantly present in the hexane extract using both maceration and Soxhlet extraction methods. Antioxidant potential was assessed through the Assay for reducing 2,2-diphenyl-1-picrylhydrazyl(DPPH). The findings demonstrate that the ethanolic extract shown greater activity for both extraction techniques, displaying an IC50 value of 222.96 μg/ml for Soxhlet extraction and 256.21 μg/ml for the maceration method.
Research on the Advantages of Digitally Transformed Supply Chains over Traditional Models
Authors: Diao Jinghan
Published: June 2024

Supply chain development is one of the hot topics of research today. Researchers have found that major enterprises have been able to flexibly master. The supply chain has become the focus of its attention, but most of the supply chain in the market is operated more traditionally. The supply chain brings many disadvantages: high cost, and operational inefficiency. The market for the supply chain how to improve its flexibility and how to meet the needs of customers lack unified knowledge. Therefore, this paper serves as a research focus on the merits of digital transformation in the supply chain vis-a-vis the conventional model. The theme of this paper is to go deeper into the advantages of a digitally transformed supply chain over the traditional model. The methodology of this paper is as follows: literature review and quantitative survey. It is found that a digital transformation supply chain is better than a traditional supply chain in terms of integration flexibility, response time, and customer satisfaction in the operation process.
Marketing charm of magic kingdom: An analysis of Disneyland’s marketing strategies
Authors: Liu Jinni , Liu Yanan
Published: June 2024

The success and impact of Disneyland, a trailblazing theme park created by Walt Disney in 1955, has been a subject of great interest and study in the field of marketing and entertainment. By identifying successful marketing practices and suggesting strategic recommendations, this essay can contribute to Disneyland’s future growth and impact in an ever-changing entertainment landscape. The essay began with an introduction to Disneyland’s historical background and significance in the theme park industry. It highlighted the park’s role in popular culture, local employment opportunities, and economic benefits. The essay then focused on a comprehensive analysis of Disneyland’s marketing strategies using the 4P model: product, price, place, and promotion. It examined how Disneyland created and delivered magical experiences, combined value-based and competitive pricing strategies, utilized physical and digital distribution channels, and employed various advertising and promotional methods. The essay concluded with strategic suggestions for Disneyland’s future development, emphasizing content innovation, theme park advancements, global expansion, and brand collaborations. The suggestions aim to solidify Disneyland’s position as a global leader in the entertainment industry, offering diverse, innovative, and captivating experiences. Overall, this essay provided insights into the marketing strategies behind Disneyland’s success and offered recommendations for its continued growth and impact.
The Development of Chinese and Foreign Literary Films – Comparison between China and foreign countries
Authors: Ji Xun
Published: June 2024

Chinese literary film is a new way of expressing Chinese native culture, inheriting and carrying forward Chinese humanistic feelings in a new form. Since 1948, Chinese literary films have experienced the development, decline and recovery of literary films, and now it is the golden stage of recovery of literary films. The new generation of directors urgently needs to learn from the successful development experience of foreign literary films, add Chinese thinking and Chinese thinking on the basis of the complete foreign art film industry chain, and build Chinese literary films into a new business card of Chinese culture in the 21st century. This article reviews the development history of art films in China, compares it with that of foreign art films, and analyzes the way out suitable for the recovery of Chinese art films by drawing on the successful experience of the development of foreign Nordic art films. Try a new way to help Chinese literary films attract more viewers at home and enter the international stage. With film as the seventh art as the carrier, this paper has stepped out of the new route to carry forward the charm of traditional Chinese culture, created China’s own good films.
Analysis of the Retention Mechanism of Knowledge Sharing Platforms - Taking Zhihu Platform as an Example
Authors: Wu Yixiao , Yuan Zixuan
Published: June 2024

With the rapid development of the Internet era, it is difficult to distinguish the truth from the falsehood of the massive amount of online information. Due to the improvement of people's material level, spiritual needs and other aspects, the users' desire for knowledge has become stronger and stronger, and knowledge sharing platforms have emerged. This paper aims to deeply analyse the retention mechanism of knowledge sharing platforms to reveal the success factors of knowledge sharing platforms. Based on existing research, this paper discusses the Zhihu platform from multiple dimensions, such as high-quality content, incentive mechanism, speech control, and pushing mechanism. This paper concludes that Zhihu continuously improves the quality of knowledge through cooperation, diversified forms, and technological innovation. User experience is guaranteed through user reach and incentive mechanisms. Regarding speech control, Zhihu balances freedom of speech and legal regulations to ensure the smooth operation of the platform. In the future, this kind of knowledge sharing platform will introduce more science and technology to improve user stickiness. Through a deep understanding of Zhihu's operation mechanism, this paper helps similar platforms understand the leaders' success factors. It provides opinions and improvement experiences for the development of similar platforms.
How Grass-roots Sports Events in the New Era Can Promote Urban Economic Development
Authors: Hou Zeyu
Published: June 2024

Grass-roots sports events in the context of the new era are gradually becoming an important influence on the conditions of urban economic development, accompanied by the introduction and practice of relevant strategies and national development goals. Sport is becoming an increasingly important part of people’s daily healthy lives. In-depth studies have found that the organization of sports events can lead to the development of related industries, and there is an important catalyst for urban economic development. However, the organization of grassroots sports events and how to truly leverage the role of sports events as a catalyst for urban development faces a series of huge problems. Therefore, government departments relevant organizations, and even individuals need to make concerted efforts to support the operation and development of urban grassroots sports events through specific and effective methods, to strengthen win-win cooperation, to attach importance to the positive role of sports events in urban development, and ultimately to give full play to the role of grassroots sports events in the context of the new era in the promotion of the city’s economic development.
The Study of the Development Path of the Ice and Snow Sports Tourism Industry in Hohhot, Inner Mongolia, Based on SWOT-PEST Matrix Analysis
Authors: Yu Youxiang
Published: June 2024

The aim of this research is to examine the current status, obstacles, and future strategies for the ice and snow sports tourism sector in Hohhot following the successful bid for the Beijing Winter Olympics. Utilizing the SWOT-PEST matrix tool and analyzing the strengths, weaknesses, opportunities, and threats of the industry in Hohhot, this paper presents a comprehensive evaluation. The study findings suggest a multi-faceted approach: (1) The ice and snow sports tourism industry in Hohhot should implement a varied growth strategy, enhancing digitalization within the sector to improve customer experiences and operational efficiency. It should also create unique branding for ice and snow initiatives, emphasizing regional distinctiveness to attract a diverse audience. (2) There is a need to concentrate on enhancing the total competitiveness of the ice and snow sports tourism industry, with a particular focus on sustainability to ensure its long-term viability. (3) It’s essential to develop appropriate development strategies that align with local circumstances, aiming to drive overall economic and social advancement within the region. This approach will help in positioning Hohhot as a premier destination for ice and snow sports tourism, leveraging its unique offerings and strategic location.
Etiology and Treatment of ASPD from Biological, Neurological and Psychotherapeutic Perspectives
Authors: Ieong Chi Hou
Published: June 2024

Antisocial Personality Disorder (ASPD) encompasses behaviors and cognitions that defy societal norms. ASPD originate in childhood and persisting into adulthood. Prior studies highlight high ASPD prevalence, especially among prison populations. Neurobiological research sheds light on structural brain abnormalities underlying ASPD's abnormal behaviors. ASPD's development links to childhood experiences, genetics, and societal factors, with familial influences playing significant roles. To be specific, numerous studies indicated that ASPD was closely related to childhood trauma and school bullying. Psychotherapy provides to be effective for ASPD's violence and abnormal behavior while drug therapy's cannot prove its effectiveness so far. Both Cognitive Behavioral Therapy (CBT) and Mentalization-Based Therapy (MBT) demonstrated efficacy in addressing ASPD, offering promising treatment avenues. The present study suggests that early intervention and education are vital for managing ASPD's impact, given its complex etiology and treatment challenges. Understanding ASPD's multifaceted nature and employing varied treatment approaches can enhance outcomes for affected individuals and society at large.
Japanese Anime Marketing Strategy in China
Authors: Zhang Rongtian
Published: June 2024

This study primarily explores the marketing strategies of Japanese animation in the Chinese market. Japanese animation has a vast audience in China. Since China's reform and opening up in the last century, Japanese animation has been extensively introduced to the Chinese market, nurturing a large community of fans since then, laying the foundation for the formation of a massive audience of animation enthusiasts today. With the rapid development of the Japanese animation market, Japanese animation, with its unique style, storylines, and production techniques, has attracted a large number of Chinese viewers. Examples include the widely known “Naruto” “One Piece” and “Detective Conan”. To better expand the share of Japanese animation in the Chinese market, Japanese animation companies have adopted a series of effective marketing strategies, including leveraging Japan's cultural soft power, collaborating on Internet platforms, diversifying promotional methods, partnering with local enterprises, and emphasizing derivative product development. These strategies have contributed to the exportation of Japanese animation. In conclusion, this paper summarizes the successful experiences of Japanese animation in the Chinese market and provides an outlook for the future.
The Inequality Caused by Economic Globalization
Authors: Du Yuqiao
Published: June 2024

Economic globalization has caused an increase in inequality between developed and developing countries. This essay will interpret the impact economic globalization has on inequality, the cause of this phenomenon, and give out suggestions for developed countries to decrease inequality by studying the case of French and Niger cooperating in Uranium mining. France, with advanced technology and massive demand for Uranium, cooperates with Niger which is a poor biased country but preserves massive amounts of Uranium. Uranium mining in Niger has caused income inequality, environmental inequality, and inequality of work conditions. Because Uranium mining created radiation and pollution which is harmful to both workers and the environment, and Niger gets profits that are lower than the average price while France gains the massive electricity produced by Uranium at a low price. The essay will explain the increase of inequality through the theory of inequality exchange, a central concept in the investigation of world system theory, and it is also a classic problem in foreign Marxist development economics research.
A Metabolomic Approach to Investigate the Effect of Phytonutrients on Proteostasis and Metabolic Pathways in Drosophila melanogaster
Authors: Mikropoulou Eleni V. , Evangelakou Zoi , Trougakos Ioannis P. , Halabalaki Maria
Published: June 2024

The use of Drosophila melanogaster as a biological platform to study the effect of diet and food bioactives on the metabolome remains a highly unexplored subject. Aiming to establish alternative solutions for the investigation of nutritional interventions with bioactive natural products by employing LC-MS-based metabolomics approaches, we assessed the effect of a phytonutrient-rich extract from the endemic Mediterranean plant Cichorium spinosum (stamnagkàthi) on a Drosophila population. The extractʼs modulating effect on the proteostasis network and metabolism of young D. melanogaster flies was evaluated. Furthermore, an untargeted metabolomics approach, employing a C18 UPLC-ESI-Orbitrap-HRMS/MS platform, permitted the detection of several biomarkers in the metabolic profile of Drosophila’s tissues; while targeted amino acid quantification in Drosophila tissue was simultaneously performed by employing aTRAQ labeling and an
ion-pairing UPLC-ESI-SWATH-HRMS/MS platform. The detected metabolites belong to different chemical classes, and statistical analysis with chemometrics tools was utilized to reveal patterns and trends, as well as to uncover potential class-distinguishing features and possible biomarkers. Our findings suggest that Drosophila can serve as a valuable in vivo model for investigating the role of bioactive phytoconstituents, like those found in C. spinosum’s decoction, on diverse metabolic processes. Additionally, the fruit fly represents a highly effective platform to investigate the molecular mechanisms underlying sex differences in diverse aspects of nutrition and physiology in higher metazoans.
Herausforderungen mit CRPS
Authors: Burk Marion-Sybille
Published: June 2024

Es begann mit einem Sturz beim Wandern im September 2008. Ich fiel auf die Hände
und zog mir schwere Verletzungen beider Hände zu. Damit begann eine jahrelange
Odyssee mit vielen Operationen und unendlich starken Schmerzen.
Oxidation Study of Oleocanthal and Oleacein Induced by Oxone
Authors: Antoniadi Lemonia , Angelis Apostolis , Kostakis Ioannis K. , Skaltsounis Leandros A.
Published: June 2024

A selective Oxone-induced oxidation of oleocanthal and oleacein, the two main secoiridoids of olive oil, to their bis-oxidized products is described. This protocol is based on a Baeyer-Villiger mechanism and the concentration of Oxone in the final solution. The bis-oxidation of the aldehydic compounds could be extended for the synthesis of various semisynthetic analogs. The obtained acids exhibit strong antioxidant activity, being efficient free radical scavengers.
Respiratory Severity Score and Oxygen Saturation Index during the First 2 Hours of Life as Predictors for Noninvasive Respiratory Support Failure in Respiratory Distress Syndrome
Authors: Zapata Henry A. , Koueik Jack , Becker Heather L. , Lasarev Michael R. , Guthrie Scott O. , Kaluarachchi Dinushan C.
Published: June 2024

Objective Noninvasive respiratory support (NRS) failure is common in preterm infants with respiratory distress syndrome (RDS). We evaluated the utility of respiratory severity score (RSS) and oxygen saturation index (OSI) during the first 2 hours of life (HOL) as predictors for NRS failure in moderate preterm infants.

Study Design We conducted a retrospective cohort study of infants born between 280/7 and 336/7 weeks with RDS. Univariate and multivariable logistic regression analyses were used to assess whether the RSS and OSI summary measures were associated with NRS failure.

Results A total of 282 infants were included in the study. Median gestational age and birth weights were 32 weeks and 1.7 kg, respectively. Fifty-eight infants (21%) developed NRS failure at the median age of 10.5 hours. RSS and OSI summary measures in the first 2 HOL were associated with NRS failure within 72 HOL.

Conclusion RSS and OSI during the first 2 HOL can predict NRS failure. Optimal RSS and OSI cutoffs for the prediction of NRS failure need to be determined in large cohort studies.

Key Points
Long-Term Outcomes of the Obstruction Treatment in Benign and Malignant Colonic Obstruction: A Multicentre Study
Authors: Smalbroek Bo P. , Dijksman Lea M. , Bloemen Johanne , Smits Anke B.
Published: June 2024

Introduction Patients with colonic obstruction are at risk for emergency resection, which is a risk factor for increased mortality and morbidity. In left-sided obstructive colon cancer, the principle of bridge-to-surgery is already recommended to reduce complications. From this treatment strategy, the obstruction treatment is derived. In this treatment strategy, bowel wall distention is reduced by minimizing stool production through laxatives and dietary measures. Short-term outcomes have already shown promising results. This study aims to evaluate long-term outcomes in patients treated with this obstruction treatment.

Methods This is a multicenter prospective study that included patients who presented with symptomatic colonic obstruction and radiologic confirmation of obstruction between May 2019 and August 2020 in the contributing hospitals. Patients with malignant and benign colonic obstruction were included. Follow-up in this study consisted of at least 36 months. Endpoints of the study included 1- and 3-year stoma and mortality rates.

Results Ninety-eight patients were included in this study. For the overall cohort complication, reoperation, and readmission rates after one year were 37%, 14%, and 10% respectively. Overall, 3-year mortality was 21%. The presence of a stoma after 1 year was 18%, and after 3 years 17% in this cohort.

Conclusion Long-term results of this study indicate that obstruction treatment has acceptable long-term outcomes in terms of mortality and stoma rates, compared to literature on emergency surgery and bridge-to-surgery alternatives. Permanent stoma rates are lower, compared to the literature on other treatment strategies in bowel obstruction.
A Composite Seton for the Management of Fistula in Ano
Authors: Philip Sujith , Iype Geethu Rachel , Muralee Meera
Published: June 2024

Treatment of fistula in ano by seton has become less in vogue due to the complications and disadvantages associated with its use. In its place, more technically demanding and expensive procedures, with less morbidity but more recurrence, such as endorectal advancement flaps and laser, are being employed more commonly. To overcome some of the limitations of conventional seton, we have designed a composite seton. In the present study, we evaluated our experience with a composite seton made from two silastic vessel loops sutured together with 5-0 polypropylene. The composite seton was found to not present many of the disadvantages of the conventional seton. The use of the composite seton resulted in low incontinence and recurrence rates, less pain, and high quality of life. This technically simple and cheaper material may have a wider applicability.
Telemedicine in Follow-up after Spine Surgery: Need of the Hour
Authors: Totala Pankaj , Janu Vikas , Sharma Raghavendra K. , Agrawal Mohit , Garg Mayank , Gosal Jaskaran S. , Bhaskar Suryanarayanan , Jha Deepak K.
Published: June 2024

Purpose There is an acute shortage of neurosurgeons and spine surgeons especially in rural areas of low- and middle-income countries including India. Patients of spine surgery need to travel long distances for follow-up at tertiary care hospitals. This study was done to evaluate role and success rate of telemedicine in follow-up after spine surgery based on patients' diagnosis and demographic features and to identify barriers to successful telemedicine consultations.

Materials and Methods All patients undergoing spine surgeries including craniovertebral junction (CVJ) surgeries from January 2021 to June 2022 were included in the study. Success rate of telemedicine was calculated using a simple formula: Success rate of telemedicine = successful telemedicine consultations / total number of telemedicine consultation × 100. Success rate was evaluated with respect to demographic features and underlying disease-related factors.

Results Eighty-four patients formed the study group in which a total of 181 video teleconsultations were done. Overall success rate of telemedicine was 82.87%. Higher socioeconomic and educational statuses were related to higher success rates of tele-consultations (p < 0.05). Difficulty in assessing neurological condition using video call in follow-up cases of CVJ and issues related to Internet communication network leading to inability to video call and share image/videos were major causes of failures.

Conclusion Telemedicine may prove an effective option for following up patients undergoing spine surgeries except CVJ, which is likely to improve further with improvements in Internet connectivity.
Immunohistochemical and histopathological analyses of cutaneous innervation to improve the diagnostic efficacy in hansen disease skin lesion
Authors: Costa Eduardo Alves Freire da , Amadeu Thaís Porto , Illarramendi Ximena , Pascarelli Bernardo , Nery José Augusto da Costa , Sales Anna Maria , Antunes Sérgio Luiz Gomes
Published: June 2024

Background The diagnosis of Hansen disease (HD) can be difficult when acid-fast bacilli are not detected in the patient's skin sample.

Objective To demonstrate that detailed morphological analysis of nonspecific inflammatory and/or noninflammatory alterations in dermal nerves as well as skin adnexa in leprosy-suspected biopsy samples could improve the efficacy of histopathological diagnosis.

Methods Patients with one to five skin lesions were enrolled in the study and classified into three groups by skin histopathology findings: Hansen disease (HD, n = 13), other diseases (OD, n = 11), and inconclusive cases (INC, n = 11). We quantified dermal nerve damage via the nerve lesion index (NLI) and PGP9.5-immunoreactive axon quantitative index in dermal nerves (AQI). We also measured inflammatory involvement of adnexa in cutaneous samples as indirect evidence of HD.

Results We observed a higher median endoneurial inflammatory infiltrate NLI (HD = 0.5; INC = 0; OD = 0; p < 0.001) and more frequent inflammatory involvement of skin adnexa in samples of the HD group compared with those of the INC and OD groups (HD = 7; INC = 1; OD = 0). However, samples from the INC and OD groups also showed inflammatory and noninflammatory damage of dermal nerves, with 2 or more kinds of alterations in nerves in the same sample (respectively: INC = in 1 and 2 samples; OD = in 3 and 5 respectively). The quantification of PGP9.5-immunoreactive axons in dermal nerves revealed no difference between the groups.

Conclusion A detailed morphological analysis of cutaneous nerves in lesions with a suspicion of HD enabled us to select patients with nonspecific inflammatory or non-inflammatory lesions in the dermal nerves in the INC and OD groups, so they may be clinically monitored aiming at a possible future diagnosis of the disease. These INC and OD patients cannot have the HD diagnosis definitely excluded, and HD may coexist with another disease as a comorbidity.