bluuebunny/crossref_metadata_2025 huggingface dataset:
System Identification–Based Adaptive Real-Time Simulators for Power Electronic Converters—Application to Three-Phase and NPC Inverters
Authors: Idkhajine Lahoucine , Aarab Mohamed , Monmasson Eric
Published: February 2023

This paper deals with the real-time simulation of power electronic converters. It discusses a new approach for designing embedded real-time simulators (eRTSs) that approximate the static and dynamic behavior of a power converter at the switching scale. The main concept is to approximate the voltage/current experimental characteristics of each switch using dedicated transfer functions obtained after a system identification process. The adaptive feature of such eRTS consists of developing varying and online reconfigurable coefficients transfer functions. The main potential of doing so is the possibility of reconfiguring the model according to the actual electrical/thermal environment where the power converter is used. Then, the latter is subdivided into independent switching cells, represented by dedicated RT models that are fully parallelized. Furthermore, using FPGA devices makes it possible to achieve very low latencies and, consequently, a short simulation time step. Previous work was published in this context, where this approach was deeply described and tested with half-bridge DC–DC, full-bridge DC–AC, and multi-level cascaded H-bridge (five-level and nine-level) power converters. This paper recalls the main basics and, more importantly, discusses additional case studies, namely a three-phase voltage source inverter, a half-bridge NPC (neutral-point clamped) inverter, and a three-phase NPC inverter.
FRT Capability Enhancement of Offshore Wind Farm by DC Chopper
Authors: Rashid Gilmanur , Ali Mohd Hasan
Published: February 2023

Offshore wind farms (OWF) are establishing their position to be the next strategy to expand the growth horizon of wind power production. For proper integration of OWFs into the existing grid, the voltage source converter (VSC)-based high voltage direct current (HVDC) transmission is being vastly utilized. For the stable operation of the existing grid, these VSC-HVDC-connected OWFs need to abide by the fault ride through (FRT) grid codes. Though there are many proposed solutions to tackle the FRT problem of the onshore wind farms, all of them cannot be applied to the OWFs. The OWFs cannot respond to the onshore faults depending solely on local measurements. Additionally, there are very few techniques available for FRT capability enhancement of the doubly fed induction generator (DFIG)-based OWFs. One notable solution is the use of the DC chopper resistor across the HVDC line. No intelligent controller is yet to be reported for better control of the DC chopper resistor. To enhance the performance of the DC chopper resistor in enhancing the FRT capability of the DFIG-based OWF, a particle swarm optimization (PSO)-based nonlinear controller is proposed. Simulations carried out in the Matlab/Simulink environment reveal that the PSO-optimized nonlinear controller-based DC chopper is very effective in maintaining the FRT of the DFIG-based OWF systems. Additionally, the proposed method provides better FRT performance than that of the conventional controller-based DC chopper.
Economic Performance Indicators for a Geothermal Aquatic Center in Victoria, Australia
Authors: Fu Boxiang , Beardsmore Graeme , Webster Rachel
Published: February 2023

The Gippsland Regional Aquatic Centre (GRAC) opened in the town of Traralgon, Victoria, Australia early in 2021. The GRAC utilizes a geothermal energy heating system as an alternative to conventional natural gas furnaces. We have examined 12 full months of heat production from the geothermal system of the GRAC and compared its economic performance against equivalent heat production by natural gas. The geothermal system—the first of its kind in Victoria—operated at >95% availability over its first year of operation. Our economic assessment indicates that the breakeven price for the geothermal energy is about 35% the equivalent price of natural gas and the payback period for the geothermal system is about five years. The results justify the initial capital outlay by Latrobe City Council and are likely to stimulate further development of geothermal heat systems in the region.
Risk Dependence and Risk Spillovers Effect from Crude Oil on the Chinese Stock Market and Gold Market: Implications on Portfolio Management
Authors: Mo Bin , Meng Juan , Wang Guannan
Published: February 2023

We analyze crude oil’s dependence and the risk spillover effect on the Chinese stock market and the gold market. We compare both static and dynamic copula functions and calculate the average upward and downward spillover effect using the time-varying Copula model and the conditional value-at-risk approach. By utilizing daily data on crude oil prices, China’s stock market, and the gold market, we observe an asymmetric spillover effect: the downside spillover effects from crude oil prices on the Chinese stock market and gold market are larger than the upside spillover effect. We then identify changes in the structure of the sample periods and calculate the dynamic conditional correlation between them. In addition, we explore the optimal weight and hedge ratios in diversified portfolios to mitigate potential risks. Our results suggest that investors and portfolio managers should frequently adjust their portfolio strategies, particularly during extreme events like COVID-19, when financial assets become more volatile. Furthermore, crude oil can help reduce the risk in the Chinese stock market and gold market to some extent during different sub-periods.
Wind Energy Conversion Systems Based on a Synchronous Generator: Comparative Review of Control Methods and Performance
Authors: Raouf Amir , Tawfiq Kotb B. , Eldin Elsayed Tag , Youssef Hossam , El-Kholy Elwy E.
Published: February 2023

Recently, controlling a wind energy conversion system (WECS) under fluctuating wind speed and enhancing the quality of power delivered to the grid has been a demanding challenge for many researchers. This paper provides a comprehensive review of synchronous generator-based WECSs. This paper will investigate the growth of wind energy in Egypt and throughout the world, as well as the technological and financial significance of wind energy. The block diagram of a typical grid-connected WECS, power control techniques, characteristic power curve-based maximum power point tracking (MPPT), and MPPT techniques are also presented in this study. Moreover, this study compares different power converter topologies for grid-connected and independent WECSs that use a permanent magnet synchronous generator (PMSG).
Economic Value Estimation of Biogas Utilization in Public Wastewater Treatment Plants of the Republic of Korea
Authors: Jung Deok-Kyeom , Park Sung-Min
Published: February 2023

This paper presents economic value estimation of improved biogas utilization systems of public wastewater treatment plants in Republic of Korea. Since a large amount of biogas produced at digestion facilities is being wasted as a by-product, the biogas energy utilization system needs to be enhanced. In this paper, three operating options able to utilize the produced biogas are proposed, and then their monetary benefits are estimated by means of net present value calculation. Real operational data from the public wastewater treatment plant located in Sejong city, Republic of Korea, is used to reflect a variation of the rated daily gas production and its concentration according to the weather and seasons, resulting in calculating more reliable results. Additionally, to minimize the estimation errors due to uncertainties of the gas concentration and the gas selling price, a Monte Carlo simulation considering the variation of critical input data is carried out. As a result, the proposed approach can lead to better decisions in selecting the suitable biogas utilization system by forecasting the ranges of possible economic values.
Discontinuous Deformation Characteristics of Deep Buried Roadway Roofs and Linkage Control of Thick Layer Cross-Boundary Anchorage: A Case Study
Authors: Han Changliang , Zhang Nong , Yang Houqiang , Zhao Qifeng , Song Kai
Published: February 2023

After deep mining, the discontinuous deformation characteristics of roadway roofs become more and more obvious, resulting in the emergence of separation fractures in the rock mass, which seriously affects the stability of the roof rock mass. By taking the air return roadway 21204 (ARR 21204) in Hulusu Coal Mine as the engineering background, this article reveals the discontinuous deformation characteristics of deep buried roadway roofs through field research, numerical simulation, theoretical analysis and engineering practice. After roadway excavation, the rock masses in different shallow roof horizons show different degrees of stress unloading, resulting in the occurrence of discontinuous deformation phenomena in rock masses. With the rise of the roof rock horizon, the degree of discontinuous deformation fades away until a continuous deformation zone with small deformation and stable rock strata appears. In addition, with the increase in the roadway buried depth, the extent of the discontinuous deformation of the roof and its extended range tend to increase. In view of the discontinuous deformation control of the roof, the technology of linkage control of thick layer cross-boundary anchorage is proposed. By establishing the thick anchorage ring of the roof, the bolts cross the discontinuous deformation zone to support the stable rock strata in the deep continuous deformation zone, thereby realizing the linkage control of the large and small displacement of the rock masses in these two zones and limiting the progressive damage of the roof rock mass from shallow to deep. The industrial test shows that the scope of the separation fracture zone on the roof is controlled at the shallow stratum of 0.85 m due to the great decrease in the surface displacement of roadway, which effectively restricts the progressive upward extension of the discontinuous deformation zone of the roof. The research results can provide references for the safe and efficient control of roadway roofs under deep mining conditions.
Multi-Trait Selection and Stability in Norway Spruce (Picea abies) Provenance Trials in Romania
Authors: Alexandru Alin-Madalin , Mihai Georgeta , Stoica Emanuel , Curtu Alexandru Lucian
Published: February 2023

Provenance trials replicated in multiple environments allow the selection of populations with high and stable performances. In this study, two methods have been applied to select stable Norway spruce provenances with high performances in three provenance trials established in Romania in 1972, where 81 provenances have been tested. Four traits were assessed: total and pruned height, diameter at breast height and survival rate. Two multi-trait indices have been used: multi-trait genotype-ideotype distance index (MGIDI) for each provenance trial and multi-trait stability index (MTSI) across provenance trials. The selection differential was between 0.2 and 17.8% better than each site means. Several Norway spruce provenances showed stability and high performances, as confirmed by both selection indices. Our results provide valuable information for the genetic improvement program and seed transfer guidelines based on assisted migration in this ecologically and economically important forest tree species.
Seasonal Variation in Chemical Composition, Ruminal Fermentation, and Biological Characteristics of Paulownia shan tong: In Vitro Potential Use by Sheep and Goats
Authors: Ammar Hajer , Kholif Ahmed E. , Missaoui Manel , Zoabi Halimeh , Ghzayel Soha , de Haro-Martí Mario , de Almeida Teixeira Izabelle Auxiliadora Molina , Fkiri Sondos , Khouja Mohamed Larbi , Fahmy Mahmoud , Gouda Gouda A. , López Secundino , Chahine Mireille
Published: February 2023

This study was conducted to determine the seasonal variation (two seasonal harvests during winter and spring) in some chemical and biochemical characteristics of Paulownia shan tong leaves. To achieve this, we analyzed the chemical composition in terms of dry matter (DM), organic matter (OM), crude protein (CP), cell-wall content (neutral detergent fiber (NDF)), acid detergent fiber (ADF), acid detergent lignin (ADL), and lipids. The phenolic compounds (PC) and antioxidant activity (AA) of the leaves were also determined. In vitro gas production (GP) and nutrient degradability were evaluated using two ruminal-content donors (sheep and goats). Higher (p < 0.05) antioxidant activities were observed in the winter harvest of P. shan tong, while higher concentrations of OM (90.5%), lipids (3.02%), NDF (69.7%), ADF (54.8%), ADL (35.4%), total flavonoids (0.45 mg catechin equivalents/mg DM), and total phenolics (2.52 mg gallic acid equivalents/mg DM) were observed in the spring harvest. Higher asymptotic GP and rate of GP (p < 0.05) were observed when the leaves were incubated with rumen liquor of goats compared to sheep; however, higher (p < 0.05) lag time of GP and half-time of GP were observed with rumen liquor from sheep. Moreover, higher asymptotic GP, rate of GP, and half-time of GP were observed with the winter harvest of P. shan tong. Higher (p < 0.001) metabolizable energy, OM degradability, and microbial protein supplies were obtained when the leaves were incubated with rumen fluids from goats and from the winter harvest of P. shan tong compared to the spring harvest. In conclusion, based on the chemical composition and the kinetics of in vitro gas production, P. shan tong leaves seem to be characterized by a good nutritive value and could be considered as an alternative feed resource for ruminants.
Fibrillogenesis and Hydrogel Formation from Fibrinogen Induced by Calcium Salts
Authors: Hense Dominik , Strube Oliver I.
Published: February 2023

Fibrin is considered a highly promising biomaterial for manifold medical applications. Although it is a well-established material in this field, the required enzyme thrombin bears some striking downsides such as high costs and health risks. Current research discovers more and more ways to use fibrin’s precursor fibrinogen as a substitute. Fibrinogen’s full potential is, however, only retained when using it as fibrous gel, as it is the case for fibrin. In our previous work, we introduced such a kind of material for the first time. This material, called pseudo-fibrin, shows striking similarities to fibrin regarding its supramolecular structure and is created in a facile salt-induced process, which we further improved in this study. In particular, we shine light on the role of Ca2+ in pseudo-fibrin buildup, which turned out to drastically improve the outcome. Never before has it been observed that Ca2+ can induce fibrillogenesis and the gelation of native, enzyme-free fibrinogen. Enzyme catalysis was ruled out by the addition of thrombin and factor XIII inhibitors. Even more striking, Ca2+ induces gelation even under physiological conditions, leading again to stable and fibrous hydrogels. Although this latter approach is possibly co-induced by residual factor XIII, the resulting gels are for the first time recognized as promising materials and not discounted as unwanted side effects. The finding that these gels again consist of fibers especially renders a new perspective on the role of factor XIII and fibrinogen’s well-known Ca2+ binding sites. In this study, we aim to provide first insights into this highly feasible material and its characteristics.
Pathogenicity Analysis of a Novel Variant in GTPBP3 Causing Mitochondrial Disease and Systematic Literature Review
Authors: Zhang Qin , Ouyang Qianqian , Xiang Jingjing , Li Hong , Lv Haitao , An Yu
Published: February 2023

Defect of GTPBP3, the human mitochondrial tRNA-modifying enzyme, can lead to Combined Oxidative Phosphorylation Deficiency 23 (COXPD23). Up to now, about 20 different variants of the GTPBP3 gene have been reported; however, genotype–phenotype analysis has rarely been described. Here, we reported a 9-year-old boy with COXPD23 who presented with hyperlactatemia, hypertrophic cardiomyopathy, seizures, feeding difficulties, intellectual disability and motor developmental delay, and abnormal visual development. Biallelic pathogenic variants of the GTPBP3 gene were identified in this boy, one novel variant c.1102dupC (p. Arg368Profs*22) inherited from the mother and the other known variant c.689A>C (p. Gln230Pro) inherited from father. We curated 18 COXPD23 patients with GTPBP3 variants to investigate the genotype–phenotype correlation. We found that hyperlactatemia and cardiomyopathy were critical clinical features in COXPD23 and the average onset age was 1.7 years (3 months of age for the homozygote). Clinical classification of COXPD23 for the two types, severe and mild, was well described in this study. We observed arrhythmia and congestive heart failure frequently in the severe type with early childhood mortality, while developmental delay was mainly observed in the mild type. The proportion of homozygous variants (71.4%) significantly differed from that of compound heterozygous variants (18.1%) in the severe type. Compared with the variants in gnomAD, the proportion of LOFVs in GTPBP3 was higher in COXPD23 patients (48.6% versus 8.9%, p < 0.0001 ****), and 31% of them were frameshift variants, showing the LOF mechanism of GTPBP3. Additionally, the variants in patients were significantly enriched in the TrmE-type G domain, indicating that the G domain was crucial for GTPBP3 protein function. The TrmE-type G domain contained several significant motifs involved in the binding of guanine nucleotides and Mg2+, the hydrolysis of GTP, and the regulation of the functional status of GTPases. In conclusion, we reported a mild COXPD23 case with typical GTPBP3-related symptoms, including seizures and abnormal visual development seldom observed previously. Our study provides novel insight into understanding the clinical diagnosis and genetic counseling of patients with COXPD23 by exploring the genetic pathogenesis and genotype–phenotype correlation of COXPD23.
Immunoepigenetic Regulation of Inflammatory Bowel Disease: Current Insights into Novel Epigenetic Modulations of the Systemic Immune Response
Authors: Bastida Guillermo , Mínguez Alejandro , Nos Pilar , Moret-Tatay Inés
Published: February 2023

The immune system and environmental factors are involved in various diseases, such as inflammatory bowel disease (IBD), through their effect on genetics, which modulates immune cells. IBD encompasses two main phenotypes, Crohn’s disease, and ulcerative colitis, which are manifested as chronic and systemic relapse-remitting gastrointestinal tract disorders with rising global incidence and prevalence. The pathophysiology of IBD is complex and not fully understood. Epigenetic research has resulted in valuable information for unraveling the etiology of this immune-mediated disease. Thus, the main objective of the present review is to summarize the current findings on the role of epigenetic mechanisms in IBD to shed light on their potential clinical relevance. This review focuses on the latest evidence regarding peripheral blood mononuclear cells and epigenetic changes in histone modification, DNA methylation, and telomere shortening in IBD. The various identified epigenetic DNA profiles with clinical value in IBD could be used as biomarkers for more accurately predicting disease development, treatment response, and therapy-related adverse events. Ultimately, the information presented here could be of potential relevance for future clinical practice in developing more efficient and precise medicine to improve the quality of life for patients with IBD.
Effect of Dietetic Obesity on Testicular Transcriptome in Cynomolgus Monkeys
Authors: Zhang Yanru , Qi Jia , Zhao Juan , Li Miaojing , Zhang Yulin , Hu Huizhong , Wei Liangliang , Zhou Kai , Qin Hongyu , Qu Pengxiang , Cao Wenbin , Liu Enqi
Published: February 2023

Obesity is a metabolic disorder resulting from behavioral, environmental and heritable causes, and can have a negative impact on male reproduction. There have been few experiments in mice, rats, and rabbits on the effects of obesity on reproduction, which has inhibited the development of better treatments for male subfertility caused by obesity. Nonhuman primates are most similar to human beings in anatomy, physiology, metabolism, and biochemistry and are appropriate subjects for obesity studies. In this investigation, we conducted a transcriptome analysis of the testes of cynomolgus monkeys on high-fat, high-fructose, and cholesterol-rich diets to determine the effect of obesity on gene expression in testes. The results showed that the testes of obese monkeys had abnormal morphology, and their testes transcriptome was significantly different from that of non-obese animals. We identified 507 differentially abundant genes (adjusted p value < 0.01, log2 [FC] > 2) including 163 up-regulated and 344 down-regulated genes. Among the differentially abundant genes were ten regulatory genes, including IRF1, IRF6, HERC5, HERC6, IFIH1, IFIT2, IFIT5, IFI35, RSAD2, and UBQLNL. Gene ontology (GO) and KEGG pathway analysis was conducted, and we found that processes and pathways associated with the blood testes barrier (BTB), immunity, inflammation, and DNA methylation in gametes were preferentially enriched. We also found abnormal expression of genes related to infertility (TDRD5, CLCN2, MORC1, RFX8, SOHLH1, IL2RB, MCIDAS, ZPBP, NFIA, PTPN11, TSC22D3, MAPK6, PLCB1, DCUN1D1, LPIN1, and GATM) and down-regulation of testosterone in monkeys with dietetic obesity. This work not only provides an important reference for research and treatment on male infertility caused by obesity, but also valuable insights into the effects of diet on gene expression in testes.
The Recent Discovery, Research, and Restoration of Medieval and Renaissance Frescoes in Riga Castle—A Treasure to the Baltic Region
Authors: Rasiņa Madara , Spārītis Ojārs , Přikrylová Jiřina , Racek Martin , Kopecká Ivana , Svobodová Eva , Přikryl Richard
Published: February 2023

One of the most important castles of the medieval Teutonic Order—Riga Castle in Latvia—is currently undergoing extensive reconstruction work. This study attempts to summarize recent information about the medieval fresco in the chapel and decorative paintings (17th century CE) on the vaults and vault consoles of the refectory that were found during this work. The restorers acquired a combined knowledge of the materials during the pre-restoration research as well as during the restoration process. This, together with the art historian’s viewpoint, and analytical study conducted by chemical technologist of art restoration and material scientists, allowed for an understanding of the materials present, as well as for a determination of the most probable techniques used for the creation of the frescoes. Based on the results presented in this study, the investigated fresco was mostly created using local materials for the plaster and imported ones for pigments, specifically azurite, malachite, and cinnabar. The restoration works, and the possible iconographic meaning of the remaining fragments of the medieval painting, are also discussed.
Threshold Effect of Environmental Regulation and Green Innovation Efficiency: From the Perspective of Chinese Fiscal Decentralization and Environmental Protection Inputs
Authors: Liu Liang , Zhao Yuting , Gong Xiujuan , Liu Shu , Li Mengyue , Yang Yirui , Jiang Pan
Published: February 2023

In the context of China’s 14th Five-Year Plan and 2035 visionary goals of national economic and social development, to achieve the national dual carbon goals, an innovation-driven green development strategy must be implemented, and the relationship between environmental regulation and green innovation efficiency must be clarified. Based on the DEA-SBM model, in this study, we measured the green innovation efficiency of 30 provinces and cities in China from 2011 to 2020 by introducing environmental regulation as the core explanatory variable, and two threshold variables, environmental protection input and fiscal decentralization, to empirically analyze the threshold effect of environmental regulation on green innovation efficiency. We found that: (1) The green innovation efficiency of 30 provinces and municipalities in China is spatially distributed as strong in the east and weak in the west. (2) A double-threshold effect exists with environmental protection input as the threshold variable. Environmental regulation showed an inverted N-shaped relationship of first inhibiting, then promoting, and finally inhibiting green innovation efficiency. (3) A double-threshold effect exists with fiscal decentralization as the threshold variable. Environmental regulation showed an inverted N-shaped relationship of inhibiting, promoting, and then inhibiting green innovation efficiency. The study results provide theoretical guidance and practical reference for China to achieve the dual carbon goal.
Activities Carried Out during the First COVID-19 Lockdown by Italian Citizens
Authors: Paltrinieri Sara , Bressi Barbara , Mazzini Elisa , Fugazzaro Stefania , Rondini Ermanno , Giorgi Rossi Paolo , Costi Stefania
Published: February 2023

The SARS-CoV-2 pandemic has altered how citizens engage in activities. This study describes the new activities citizens engaged in during the first lockdown, factors that helped them cope with the confinement, the supports they used the most, and which supports they would have liked to receive. This cross-sectional study consists of an online survey made of 49 questions that was completed by the citizens of the province of Reggio Emilia (Italy) from 4 May until 15 June 2020. The outcomes of this study were explored by focusing on four of the survey questions. Of the 1826 citizens who responded, 84.2% had started new leisure activities. Males, participants who lived in the plain or foothills, and those who experienced nervousness engaged less in new activities, while those whose employment status changed, whose lifestyle worsened, or whose use of alcohol increased engaged in more activities. The support of family and friends, leisure activities, continuing to work, and an optimistic attitude were perceived to be of help. Grocery delivery and hotlines providing any type of information and mental health support were used frequently; a lack of health and social care services and of support in reconciling work with childcare was perceived. Findings may help institutions and policy makers to better support citizens in any future circumstances requiring prolonged confinement.
Understanding Post-Adoption Behavioral Intentions of Mobile Health Service Users: An Empirical Study during COVID-19
Authors: Jiang Yanmei , Lau Antonio K. W.
Published: February 2023

This study aims to understand the post-adoption behaviors of mobile health (m-Health) service users during the COVID-19 pandemic. Drawing on the stimulus-organism-response framework, we examined the effects of user personality traits, doctor characteristics, and perceived risks on user continuance intentions and positive word of mouth (WOM) when using m-Health, as mediated by cognitive and emotional trust. The empirical data were collected via an online survey questionnaire from 621 m-Health service users in China and were verified with partial least squares structural equation modeling. The results showed that personal traits and doctor characteristics were positively associated and the perceived risks were negatively associated with both cognitive and emotional trust. Both cognitive and emotional trust significantly influenced users’ post-adoption behavioral intentions in terms of continuance intentions and positive WOM, with different magnitudes. This study provides new insights for the promotion of the sustainable development of m-Health businesses after or during the pandemic.
Modeling Production-Living-Ecological Space for Chengdu, China: An Analytical Framework Based on Machine Learning with Automatic Parameterization of Environmental Elements
Authors: Cao Qi , Tang Junqing , Huang Yudie , Shi Manjiang , van Rompaey Anton , Huang Fengjue
Published: February 2023

Cities worldwide are facing the dual pressures of growing population and land expansion, leading to the intensification of conflicts in urban productive-living-ecological spaces (PLES). Therefore, the question of “how to dynamically judge the different thresholds of different indicators of PLES” plays an indispensable role in the studies of the multi-scenario simulation of land space changes and needs to be tackled in an appropriate way, given that the process simulation of key elements that affect the evolution of urban systems is yet to achieve complete coupling with PLES utilization configuration schemes. In this paper, we developed a scenario simulation framework combining the dynamic coupling model of Bagging-Cellular Automata (Bagging-CA) to generate various environmental element configuration patterns for urban PLES development. The key merit of our analytical approach is that the weights of different key driving factors under different scenarios are obtained through the automatic parameterized adjustment process, and we enrich the study cases for the vast southwest region in China, which is beneficial for balanced development between eastern and western regions in the country. Finally, we simulate the PLES with the data of finer land use classification, combining a machine learning and multi-objective scenario. Automatic parameterization of environmental elements can help planners and stakeholders understand more comprehensively the complex land space changes caused by the uncertainty of space resources and environment changes, so as to formulate appropriate policies and effectively guide the implementation of land space planning. The multi-scenario simulation method developed in this study has offered new insights and high applicability to other regions for modeling PLES.
Improving Participation among Youth with Disabilities within Their Unique Socio-Cultural Context during COVID-19 Pandemic: Initial Evaluation
Authors: Golos Anat , Zyger Chani , Lavie-Pitaro Yael , Anaby Dana
Published: February 2023

Background: Participation in meaningful activities is important for quality of life among youth with disabilities; yet participation is often restricted during adverse times. This study aimed to explore the effectiveness of the Pathways and Resources for Engagement and Participation (PREP) intervention among ultra-Orthodox Jewish Israeli youth with disabilities during the COVID-19 pandemic. Methods: A 20-week single-subject research design with multiple baselines measuring participation goals/activities was employed with two youths (15 and 19 years old) combining quantitative and qualitative descriptive data. Changes in participation levels were measured biweekly using the Canadian Occupational Performance Measure; COPM; participation patterns were measured using the Participation and Environment Measure—Children and Youth; PEM-CY pre- and post-intervention; parents’ satisfaction was measured using the Client Satisfaction Questionnaire, CSQ-8. Semi-structured interviews were conducted post-intervention. Results: Both participants significantly improved participation in all selected goals and participation patterns, and were highly satisfied with the intervention. The interviews revealed additional information on personal and environmental barriers, factors supporting intervention, and intervention effects. Conclusions: The results indicated that an environment-centered and family-centered approach can potentially improve the participation of youths with disabilities within their unique socio-cultural context, during adverse times. Flexibility, creativity, and collaboration with others also contributed to intervention success.
A Single Bout of Remote Ischemic Preconditioning Suppresses Ischemia-Reperfusion Injury in Asian Obese Young Men
Authors: Jang Min-Hyeok , Kim Dae-Hwan , Han Jean-Hee , Kim Jahyun , Kim Jung-Hyun
Published: February 2023

Remote ischemic preconditioning (RIPC) has been shown to minimize subsequent ischemia-reperfusion injury (IRI), whereas obesity has been suggested to attenuate the efficacy of RIPC in animal models. The primary objective of this study was to investigate the effect of a single bout of RIPC on the vascular and autonomic response after IRI in young obese men. A total of 16 healthy young men (8 obese and 8 normal weight) underwent two experimental trials: RIPC (three cycles of 5 min ischemia at 180 mmHg + 5 min reperfusion on the left thigh) and SHAM (the same RIPC cycles at resting diastolic pressure) following IRI (20 min ischemia at 180 mmHg + 20 min reperfusion on the right thigh). Heart rate variability (HRV), blood pressure (SBP/DBP), and cutaneous blood flow (CBF) were measured between baseline, post-RIPC/SHAM, and post-IRI. The results showed that RIPC significantly improved the LF/HF ratio (p = 0.027), SBP (p = 0.047), MAP (p = 0.049), CBF (p = 0.001), cutaneous vascular conductance (p = 0.003), vascular resistance (p = 0.001), and sympathetic reactivity (SBP: p = 0.039; MAP: p = 0.084) after IRI. However, obesity neither exaggerated the degree of IRI nor attenuated the conditioning effects on the measured outcomes. In conclusion, a single bout of RIPC is an effective means of suppressing subsequent IRI and obesity, at least in Asian young adult men, does not significantly attenuate the efficacy of RIPC.
Internet Gaming Disorders and Early Onset Psychosis in Young People: A Case Study and Clinical Observations
Authors: Ricci Valerio , De Berardis Domenico , Maina Giuseppe , Martinotti Giovanni
Published: February 2023

Background: Over the last ten years, the video game industry has grown exponentially, involving about 2.5 billion young adults in the world. The estimated global prevalence of gaming addiction has been reported to be 3.5% ranging from 0.21% to 57.5% in the general population. Moreover, during the recent COVID-19 pandemic period, school closures and stay-at-home measures have also further increased the opportunities for prolonged and intensified playing of video games. Little is known about the relationship between IGD and psychosis, and the literature is still scarce. Some characteristics of patients with psychosis, particularly those with a first-episode psychosis (FEP), may suggest that these individuals would be particularly liable to develop IGD. Case presentation: We report two cases of young patients with to Internet gaming disorder, experiencing early onset psychosis treated with antipsychotic therapy. Conclusion: Although it is difficult to show the specific mechanisms underlying the psychopathological alterations in IGD, it is clear that excessive exposure to video games could be a risk factor for precipitating psychosis especially in a vulnerable age group such as adolescence. Clinicians should be aware of the possibility of a higher risk of psychotic onset associated specifically with gaming disorders in very young people.
Digital Health Literacy and Person-Centred Care: Co-Creation of a Massive Open Online Course for Women with Breast Cancer
Authors: Álvarez-Pérez Yolanda , Duarte-Díaz Andrea , Toledo-Chávarri Ana , Abt-Sacks Analía , Ramos-García Vanesa , Torres-Castaño Alezandra , Rivero-Santana Amado , Perestelo-Pérez Lilisbeth
Published: February 2023

The diagnosis of breast cancer (BC) can make the affected person vulnerable to suffering the possible consequences of the use of low-quality health information. Massive open online courses (MOOCs) may be a useful and efficient resource to improve digital health literacy and person-centred care in this population. The aim of this study is to co-create a MOOC for women with BC, using a modified design approach based on patients’ experience. Co-creation was divided into three sequential phases: exploratory, development and evaluation. Seventeen women in any stage of BC and two healthcare professionals participated. In the exploratory phase, a patient journey map was carried out and empowerment needs related to emotional management strategies and self-care guidelines were identified, as well as information needs related to understanding medical terminology. In the development phase, participants designed the structure and contents of the MOOC through a Moodle platform. A MOOC with five units was developed. In the evaluation phase, participants strongly agreed that their participation was useful for the MOOC’s development and participating in the co-creation process made the content more relevant to them (experience in the co-creation); most of the participants positively evaluated the content or interface of the MOOC (acceptability pilot). Educational interventions designed by women with BC is a viable strategy to generate higher-quality, useful resources for this population.
Improving the Management of Children with Fevers by Healers in Native Rural Areas in the South of Ecuador
Authors: Bautista-Valarezo Estefanía , Espinosa Maria Elena , Arce Guerrero Narciza Eugenia , Verhoeven Veronique , Hendrickx Kristin , Michels Nele R. M.
Published: February 2023

Background: Indigenous populations are represented among the poor and disadvantaged in rural areas. High rates of infectious diseases are observed in indigenous child populations, and fever as a general symptom is common. Objective: We aim to improve the skills of healers in rural indigenous areas in the South of Ecuador for managing children with fevers. Method: We performed participatory action research (PAR) for this study with 65 healers. Results: The PAR focused on the following four phases: (1) ‘observation,’ eight focus groups were used. (2) ‘planning’ phase was developed, and with culturally reflective peer group sessions, a culturally adapted flowchart was constructed titled “Management of children with fever.” In phase (3): ‘action’, the healers were trained to manage children with fever. Phase (4): ‘evaluation’, 50% of the healers used the flowchart. Conclusions: Explicit recognition of the need for traditional healers and health professionals in indigenous communities to work together to improve health indicators such as infant mortality exists. Additionally, strengthening the transfer system in rural areas is based on knowledge and cooperation between the community and the biomedical system.
Exploring the Potential of Big Data Analytics in Urban Epidemiology Control: A Comprehensive Study Using CiteSpace
Authors: Liu Jun , Lai Shuang , Rai Ayesha Akram , Hassan Abual , Mushtaq Ray Tahir
Published: February 2023

In recent years, there has been a growing amount of discussion on the use of big data to prevent and treat pandemics. The current research aimed to use CiteSpace (CS) visual analysis to uncover research and development trends, to help academics decide on future research and to create a framework for enterprises and organizations in order to plan for the growth of big data-based epidemic control. First, a total of 202 original papers were retrieved from Web of Science (WOS) using a complete list and analyzed using CS scientometric software. The CS parameters included the date range (from 2011 to 2022, a 1-year slice for co-authorship as well as for the co-accordance assessment), visualization (to show the fully integrated networks), specific selection criteria (the top 20 percent), node form (author, institution, region, reference cited, referred author, journal, and keywords), and pruning (pathfinder, slicing network). Lastly, the correlation of data was explored and the findings of the visualization analysis of big data pandemic control research were presented. According to the findings, “COVID-19 infection” was the hottest cluster with 31 references in 2020, while “Internet of things (IoT) platform and unified health algorithm” was the emerging research topic with 15 citations. “Influenza, internet, China, human mobility, and province” were the emerging keywords in the year 2021–2022 with strength of 1.61 to 1.2. The Chinese Academy of Sciences was the top institution, which collaborated with 15 other organizations. Qadri and Wilson were the top authors in this field. The Lancet journal accepted the most papers in this field, while the United States, China, and Europe accounted for the bulk of articles in this research. The research showed how big data may help us to better understand and control pandemics.
Factors Related to Nurse Satisfaction with Supervisor Leadership
Authors: Chang Wen-Pei , Wang Chia-Hui
Published: February 2023

The satisfaction of nurses with the leadership of their supervisors exerts a positive association with their job satisfaction. This study identified factors associated with nurse satisfaction with supervisor leadership and developed a model of causal relationships based on social exchange theory. A satisfaction scale was developed to measure how nurses felt about the leadership of their supervisor, which also assessed the validity and reliability using a cross-sectional descriptive survey questionnaire administered to nurses working in a teaching hospital in northern Taiwan. A total of 607 valid questionnaires were returned. Structural equation modeling was used to test the theoretical model of this study. Only questions that were scored above 3 were included in the scale. A total of 30 questions were placed under seven constructs of this scale upon the assessment of content validity. The results indicate that satisfaction with shift schedules, educational training, and internal communication exerted direct, significant, and positive associations with satisfaction with the supervisor leadership. Furthermore, satisfaction with policies and guidelines exerted direct, significant, and positive associations with satisfaction with internal communication and exerted indirect associations with satisfaction with supervisor leadership through internal communication. In particular, satisfaction with shift schedules and internal communication were most significantly associated with satisfaction with supervisor leadership. The results of this study offer a reference for hospital management and emphasize focusing on the arrangement of nurse shifts in all departments. The establishment of diverse communication channels can enhance the degree of nurse satisfaction with supervisor leadership.
Modulation of Heart Rate Variability following PAP Ion Magnetic Induction Intervention in Subjects with Chronic Musculoskeletal Pain: A Pilot Randomized Controlled Study
Authors: Viti Antonio , Panconi Giulia , Guarducci Sara , Garfagnini Susanna , Mondonico Mosè , Bravi Riccardo , Minciacchi Diego
Published: February 2023

Heart rate variability (HRV) analysis has emerged as a simple and non-invasive technique to indirectly evaluate the autonomic nervous system (ANS), and it is considered a sensible and advanced index of health status. Pulsed electromagnetic fields (PEMFs) are widely used in clinical settings for improving the health status of individuals with chronic musculoskeletal pain. The aim of the present single-blind, randomized, placebo-controlled parallel pilot study was to investigate the acute effect of a single session of PEMFs stimulation by a PAP ion magnetic induction (PAPIMI) device on ANS activity, as measured by HRV, in patients with chronic musculoskeletal pain, and compare such effect with that induced by a sham (control) PAPIMI inductor. Thirty-two patients were randomized into two groups: PAPIMI intervention (PAP) (n = 17) and sham PAPIMI intervention (SHAM-PAP) (n = 15). HRV was assessed before and following the interventions. The PAP group showed a significant increase in all values of the time-domain parameters (SDNN, RMSSD, NN50, and pNN50) and the HF component of HRV, suggesting a parasympathetic effect. In contrast, the SHAM-PAP group showed no significant differences in all HRV indices following the intervention. Preliminary findings suggested that PAPIMI inductor could influence ANS activity and provided initial evidence of the potential physiological response induced by the PAPIMI device.
Psychometric Testing of the CEECCA Questionnaire to Assess Ability to Communicate among Individuals with Aphasia
Authors: Martín-Dorta Willian-Jesús , García-Hernández Alfonso-Miguel , Delgado-Hernández Jonathan , Sainz-Fregel Estela , Miranda-Martín Raquel-Candelaria , Suárez-Pérez Alejandra , Jiménez-Álvarez Alejandra , Martín-Felipe Elena , Brito-Brito Pedro-Ruymán
Published: February 2023

(1) Background: The CEECCA questionnaire assesses the ability to communicate among individuals with aphasia. It was designed using the NANDA-I and NOC standardised nursing languages (SNLs), reaching high content validity index and representativeness index values. The questionnaire was pilot-tested, demonstrating its feasibility for use by nurses in any healthcare setting. This study aims to identify the psychometric properties of this instrument. (2) Methods: 47 individuals with aphasia were recruited from primary and specialist care facilities. The instrument was tested for construct validity and criterion validity, reliability, internal consistency, and responsiveness. The NANDA-I and NOC SNLs and the Boston test were used for criterion validity testing. (3) Results: five language dimensions explained 78.6% of the total variance. Convergent criterion validity tests showed concordances of up to 94% (Cohen’s κ: 0.9; p < 0.001) using the Boston test, concordances of up to 81% using DCs of NANDA-I diagnoses (Cohen’s κ: 0.6; p < 0.001), and concordances of up to 96% (Cohen’s κ: 0.9; p < 0.001) using NOC indicators. The internal consistency (Cronbach’s alpha) was 0.98. Reliability tests revealed test–retest concordances of 76–100% (p < 0.001). (4) Conclusions: the CEECCA is an easy-to-use, valid, and reliable instrument to assess the ability to communicate among individuals with aphasia.
Understand Delegates Risk Attitudes and Behaviour: The Moderating Effect of Trust in COVID-19 Vaccination
Authors: Chen Songhong , Luo Jian Ming
Published: February 2023

The continuing COVID-19 pandemic has prompted many people to receive the needed vaccines. However, how trust in vaccination affects the attitude and behavior of delegates attending a convention in Macau has yet to be determined. Accordingly, we applied quantitative method in conducting a survey involving 514 participants and analysed the data using AMOS and SPSS. The results showed that trust in vaccines has a significant impact on moderating the relationship between risk attitude and satisfaction. Trust in vaccines has a significant positive effect on involvement. Risk attitude negatively affects involvement, satisfaction, and loyalty. The major contribution of this research is the introduction of a model based on trust in vaccination. To boost delegates’ confidence to attend convention activities, governments and organizations should deliver accurate information on vaccines and pandemic risks, and that delegates should obtain accurate information about it. Lastly, unbiased and professional operators of the MICE industry also can offer precise COVID-19 vaccination information to reduce misperception and increase the security.