bluuebunny/crossref_metadata_2025 huggingface dataset:
Bifunctional terahertz modulator for beam steering and broadband absorption based on a hybrid structure of graphene and vanadium dioxide
Authors: Liu Wenwen , Xu Jiashuai , Song Zhengyong
Published: July 2021

A bifunctional metamaterial is proposed based on a hybrid graphene and vanadium dioxide (VO2) configuration, which can realize a dynamic switch between beam steering and broadband absorption. The structure consists of a VO2 square, graphene patch, topas spacer, VO2 film, topas spacer, and metal substrate. When VO2 is in the metallic state, the structure serves as a coding metamaterial. By engineering different sizes of the top VO2 square and adjusting the Fermi energy level of graphene, the incident wave is scattered in different patterns. When VO2 is in the dielectric state, the structure serves as a broadband absorber. By changing the Fermi energy level of graphene from 0.0 eV to 0.9 eV, absorptance can be gradually changed and working bandwidth widens. There is an absorption band with near 100% absorptance from 0.9 THz to 1.35 THz when the Fermi energy level is 0.73 eV. And the designed broadband absorber is polarization-insensitive within the incident angle of 50°. Our work may show great potential in applications such as terahertz switching and modulation.
Miniaturized spectroscopy with tunable and sensitive plasmonic structures
Authors: Liang Li , Zheng Qilin , Wen Long , Cumming David R. S. , Chen Qin
Published: July 2021

A broad linewidth and a lack of spectral analysis limit the applications of plasmonic sensors. In this Letter, a plasmonic sensor with a large sensitivity in the terahertz (THz) range is proposed based on high-quality factor (

>

1000

) surface lattice resonance in subwavelength near-flat metallic gratings. Moreover, such a highly selective spectral manipulating scheme, plus the greatly localized plasmonic resonance, enables miniaturized spectroscopy based on a single detector by integrating an electro-optical material with the gratings. A spectral resolution of 0.1 GHz at a center frequency of 1.1 THz is predicted showing a four times improvement of measuring efficiency. This technique shows promising potential in on-site matter inspection and point-of-care testing.
Transient electromagnetic singularities in random three-dimensional optical fields
Authors: Freund Isaac
Published: July 2021

We show that on all generic circular or elliptical paths in a random three-dimensional electromagnetic field, the electric and magnetic field vectors generate a cylinder throughout most of the optical cycle. At some point in the cycle, however, this cylinder transforms into a twisted ribbon with two sequential 180° twists. This ribbon exists for a short time and then unwinds, regenerating the cylinder. We discuss how and why these structures form and what determines their lifetimes.
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants
Authors: Thornton Alexis M. , Fang Lishan , Lo April , McSharry Maria , Haan David , O’Brien Casey , Berger Alice H. , Giannakis Marios , Brooks Angela N.
Published: July 2021

While advancements in genome sequencing have identified millions of somatic mutations in cancer, their functional impact is poorly understood. We previously developed the expression-based variant impact phenotyping (eVIP) method to use gene expression data to characterize the function of gene variants. The eVIP method uses a decision tree-based algorithm to predict the functional impact of somatic variants by comparing gene expression signatures induced by introduction of wild-type (WT) versus mutant cDNAs in cell lines. The method distinguishes between variants that are gain-of-function, loss-of-function, change-of-function, or neutral. We present eVIP2, software that allows for pathway analysis (eVIP Pathways) and usage with RNA-seq data. To demonstrate the eVIP2 software and approach, we characterized two recurrent frameshift variants in RNF43, a negative regulator of Wnt signaling, frequently mutated in colorectal, gastric, and endometrial cancer. RNF43 WT, RNF43 R117fs, RNF43 G659fs, or GFP control cDNA were overexpressed in HEK293T cells. Analysis with eVIP2 predicted that the frameshift at position 117 was a loss-of-function mutation, as expected. The second frameshift at position 659 has been previously described as a passenger mutation that maintains the RNF43 WT function as a negative regulator of Wnt. Surprisingly, eVIP2 predicted G659fs to be a change-of-function mutation. Additional eVIP Pathways analysis of RNF43 G659fs predicted 10 pathways to be significantly altered, including TNF-α via NFκB signaling, KRAS signaling, and hypoxia, highlighting the benefit of a more comprehensive approach when determining the impact of gene variant function. To validate these predictions, we performed reporter assays and found that each pathway activated by expression of RNF43 G659fs, but not expression of RNF43 WT, was identified as impacted by eVIP2, supporting that RNF43 G659fs is a change-of-function mutation and its effect on the identified pathways. Pathway activation was further validated by Western blot analysis. Lastly, we show primary colon adenocarcinoma patient samples with R117fs and G659fs variants have transcriptional profiles similar to BRAF missense mutations with activated RAS/MAPK signaling, consistent with KRAS signaling pathways being GOF in both variants. The eVIP2 method is an important step towards overcoming the current challenge of variant interpretation in the implementation of precision medicine. eVIP2 is available athttps://github.com/BrooksLabUCSC/eVIP2.
Spatial and temporal invasion dynamics of the 2014–2017 Zika and chikungunya epidemics in Colombia
Authors: Charniga Kelly , Cucunubá Zulma M. , Mercado Marcela , Prieto Franklyn , Ospina Martha , Nouvellet Pierre , Donnelly Christl A.
Published: July 2021

Zika virus (ZIKV) and chikungunya virus (CHIKV) were recently introduced into the Americas resulting in significant disease burdens. Understanding their spatial and temporal dynamics at the subnational level is key to informing surveillance and preparedness for future epidemics. We analyzed anonymized line list data on approximately 105,000 Zika virus disease and 412,000 chikungunya fever suspected and laboratory-confirmed cases during the 2014–2017 epidemics. We first determined the week of invasion in each city. Out of 1,122, 288 cities met criteria for epidemic invasion by ZIKV and 338 cities by CHIKV. We analyzed risk factors for invasion using linear and logistic regression models. We also estimated that the geographic origin of both epidemics was located in Barranquilla, north Colombia. We assessed the spatial and temporal invasion dynamics of both viruses to analyze transmission between cities using a suite of (i) gravity models, (ii) Stouffer’s rank models, and (iii) radiation models with two types of distance metrics, geographic distance and travel time between cities. Invasion risk was best captured by a gravity model when accounting for geographic distance and intermediate levels of density dependence; Stouffer’s rank model with geographic distance performed similarly well. Although a few long-distance invasion events occurred at the beginning of the epidemics, an estimated distance power of 1.7 (95% CrI: 1.5–2.0) from the gravity models suggests that spatial spread was primarily driven by short-distance transmission. Similarities between the epidemics were highlighted by jointly fitted models, which were preferred over individual models when the transmission intensity was allowed to vary across arboviruses. However, ZIKV spread considerably faster than CHIKV.
Increased mitochondrial protein import and cardiolipin remodelling upon early mtUPR
Authors: Poveda-Huertes Daniel , Taskin Asli Aras , Dhaouadi Ines , Myketin Lisa , Marada Adinarayana , Habernig Lukas , Büttner Sabrina , Vögtle F.-Nora
Published: July 2021

Mitochondrial defects can cause a variety of human diseases and protective mechanisms exist to maintain mitochondrial functionality. Imbalances in mitochondrial proteostasis trigger a transcriptional program, termed mitochondrial unfolded protein response (mtUPR). However, the temporal sequence of events in mtUPR is unclear and the consequences on mitochondrial protein import are controversial. Here, we have quantitatively analyzed all main import pathways into mitochondria after different time spans of mtUPR induction. Kinetic analyses reveal that protein import into all mitochondrial subcompartments strongly increases early upon mtUPR and that this is accompanied by rapid remodelling of the mitochondrial signature lipid cardiolipin. Genetic inactivation of cardiolipin synthesis precluded stimulation of protein import and compromised cellular fitness. At late stages of mtUPR upon sustained stress, mitochondrial protein import efficiency declined. Our work clarifies the enigma of protein import upon mtUPR and identifies sequential mtUPR stages, in which an early increase in protein biogenesis to restore mitochondrial proteostasis is followed by late stages characterized by a decrease in import capacity upon prolonged stress induction.
Risk of Trypanosoma cruzi infection among travellers visiting friends and relatives to continental Latin America
Authors: Sánchez-Montalvá Adrián , Salinas Catalina , Sullerio Elena , Salvador Fernando , Bosch-Nicolau Pau , Crespillo-Andújar Clara , Trigo Elena , Roure Sílvia , Valerio Lluís , Espinosa-Pereiro Juan , Molina Israel
Published: July 2021

Background

Chagas disease (CD) is regarded as a possible risk for travellers to endemic areas of continental Latin America (LA). The aim of the study is to determine the risk of Trypanosoma cruzi (TC) infection among travellers to CD endemic areas and to identify risk factors for acquiring TC infection.

Methods/Principal finding

We designed a multicenter cross-sectional study among travellers in Spain (Badalona, Barcelona and Madrid). All available adults with laboratory confirmed proof of absence of TC infection from January 2012 to December 2015 were contacted. Participants referring a trip to LA after the negative TC screening were offered to participate. We performed a standardized questionnaire of travel related factors and measurement of TC antibodies in serum. A total of 971 participants with baseline negative TC serology were selected from the microbiology records. After excluding participants not meeting inclusion criteria, eighty participants were selected. Sixty three (78.8%) were female, and the median age was 38 (IQR 34–47) years. The reason to travel was visiting friends and relatives in 98.8% of the participants. The median duration of travel was 40 (IQR 30–60) days, with 4911 participants-day of exposure. Seventy seven cases (96.25%) participants had two negative TC serology tests after the travel, two cases (2.5%) had discordant serology results (considered false positive results) and one case was infected before travelling to LA. According to our data, the upper limit of the 95% confidence interval of the incidence rate of TC acquisition in travellers is 0.8 per 1000 participant-days.

Conclusions/Significance

Among 79 non-CD travellers to TC endemic areas, we found no cases of newly acquired TC infection. The incidence rate of TC acquisition in travellers to endemic countries is less than or equal to 0.8 per 1000 traveller-days.
Physical inactivity and sitting time prevalence and trends in Mexican adults. Results from three national surveys
Authors: Medina Catalina , Jáuregui Alejandra , Hernández Cesar , Shamah Teresa , Barquera Simón
Published: July 2021

Background

Physical inactivity and high sitting time are directly related to mortality and morbidity of non-communicable diseases (NCDs). Thus, improved understanding of the prevalence and trends of these behaviors could support the design of policies and interventions for NCDs prevention.

Objective

To determine the current prevalence of physical inactivity and high sitting time, to analyze the trends, and to estimate the association of meeting/not meeting physical activity recommendations and low/high sitting time with sociodemographic characteristics and body mass index categories.

Methodology

Data from the 2018 National Health and Nutrition Survey were used. Moderate-to-vigorous physical activity (MVPA) and sitting minutes per week were calculated using the International Physical Activity Questionnaire short form (IPAQ). In total, 38,033 questionnaires of adults aged 20 to 69-year-old were analyzed. Adults were classified as physically inactive if they achieved less than 150 minutes per week of MVPA and as with high sitting time if they accumulated more than 420 minutes of sitting per day. Health and Nutrition National Surveys (ENSANUT) 2006, 2012 and 2018 were used to estimate the trends.

Results

In total, 16.5% were classified as physically inactive and 11.3% within the high sitting time category. Both prevalences increased more than 40% during the 12-y period (2006–2018). In 2018, men, younger adults, those living in urban areas, and people within the highest socioeconomical status and educational levels were more likely to not achieve physical activity recommendations and to be classified in the highest sitting time category.

Conclusion

To stop current increased trends and achieve global targets, stronger and more concerted efforts to promote physical activity and reduce sitting time are required. Thus, continued surveillance of these behaviors is necessary.
Investigating the relationship of porcine reproductive and respiratory syndrome virus RNA detection between adult/sow farm and wean-to-market age categories
Authors: Jiang Yiqun , Li Qing , Trevisan Giovani , Linhares Daniel C. L. , MacKenzie Cameron
Published: July 2021

Porcine reproductive and respiratory syndrome (PRRS) is a disease caused by the PRRS virus (PRRSV) that has spread globally in the last 30 years and causes huge economic losses every year. This research aims to 1) investigate the relationship between the PRRSV detection in two age categories (wean-to-market and adult/sow farm), and 2) examine the extent to which the wean-to-market PRRSV positive rate forecasts the adult/sow farm PRRSV positive rate. The data we used are the PRRSV RNA detection results between 2007 and 2019 integrated by the US Swine Disease Reporting System project that represent 95% of all porcine submissions tested in the US National Animal Health Network. We first use statistical tools to investigate to what extent the increase in PRRSV positive submissions in the wean-to-market is related to the PRRSV increase in adult/sow farms. The statistical analysis confirms that an increase in the PRRSV positive rate of wean-to-market precedes the increase in the adult/sow farms to a large extent. Then we create the dynamic exponentially weighted moving average control charts to identify out-of-control points (i.e., signals) in the PRRSV rates for both wean-to-market and adult/sow farms. This control-chart-based analysis finds that 78% of PRRSV signals in the wean-to-market are followed by a PRRSV rate signal in the adult/sow farms within eight weeks. We expect that our findings will help the producers and veterinarians to justify and reinforce the implementation of bio-security and bio-contaminant practices to curb disease spread across farms.
Weight gain during twin pregnancy with favorable pregnancy outcomes in Japan: A retrospective investigation for new criteria based on perinatal registry data
Authors: Obata Soichiro , Shimura Mai , Misumi Toshihiro , Nakanishi Sayuri , Shindo Ryosuke , Miyagi Etsuko , Aoki Shigeru
Published: July 2021

In 2009, the United States Institute of Medicine (IOM) reported the optimal gestational weight gain (GWG) during twin pregnancy based on the pre-pregnancy body mass index (BMI). However, there are ethnic variations in the relationship between GWG and pregnancy outcomes. We aimed to establish the criteria for optimal GWG during twin pregnancy in Japan. The study included cases of dichorionic diamniotic twin pregnancy registered in the Japan Society of Obstetrics and Gynecology Successive Pregnancy Birth Registry System between 2013 and 2017. We analyzed data for cases wherein both babies were appropriate for gestational age and delivered at term. Cases were classified into four groups based on the pre-pregnancy BMI: underweight (BMI <18.5 kg/m2), normal weight (18.5 kg/m2 ≤BMI< 25.0 kg/m2), overweight (25.0 kg/m2 ≤BMI< 30.0 kg/m2), and obese (BMI ≥30.0 kg/m2) and we calculated the 25th–75th percentile range for GWG for the cases. The 3,936 cases were included. The GWG ranges were 11.5–16.5 kg, 10.3–16.0 kg, 6.9–14.7 kg, and 2.2–11.7 kg in the underweight, normal weight, overweight, and obese groups, respectively. Thus, in the current study, the optimal GWG during twin pregnancy was lower than that specified by the IOM criteria. Factoring this in maternal management may improve the outcomes of twin pregnancies in Japan.
Outpatient nursing support for self-monitoring in patients with chronic heart failure
Authors: Taniguchi Chinatsu , Seto Natsuko , Shimizu Yasuko
Published: July 2021

Background

Early symptoms of worsening heart failure are difficult for patients to detect and manage, contributing to the high readmission rate for worsening heart failure. Thus, it is important to promote self-monitoring and to support patients in recognizing and interpreting their symptoms. This study aimed to explore the ways in which specialized nurses in the outpatient setting provide support for self-monitoring in patients with chronic heart failure in Japan.

Methods

This exploratory study adopted a qualitative study design. The participants were a convenience sample of five nurses certified in chronic heart failure nursing and one advanced practice nurse certified in chronic care nursing, all with experience in outpatient nursing in Japan. Data were collected from June 2017 to October 2017 through semi-structured one-on-one interviews and were analyzed using an established qualitative inductive method.

Results

The analysis identified seven themes describing the nursing support provided by the study participants. Among these were three themes describing different forms of direct support for self-monitoring: “Encourage patients to reflect on their own,” “Support touching the body and developing body awareness,” and “Support sharing the task.” Two themes described practice perspectives: “Support self-monitoring that is not overly sensitive” and “Support connection with the patient’s life.” Two final themes described contextual factors in the outpatient care setting: “Struggling with constraints and powerlessness” and “Building a support system in the outpatient setting.”

Conclusions

The findings provide a practice for nurses promoting self-monitoring in patients with chronic heart failure in the outpatient setting. The study findings inform and provide goals for the support of self-monitoring in patients with heart failure and also, suggest the need to establish a strong support system for outpatient care in Japan.
General self-efficacy in individuals with visual impairment compared with the general population
Authors: Brunes Audun , Hansen Marianne B. , Heir Trond
Published: July 2021

Background

Knowledge about self-efficacy and its significance for the quality of life of people with visual impairment is lacking. The aims of the study were to compare general self-efficacy in individuals with visual impairment with the general population, and to investigate the association between self-efficacy and life satisfaction.

Methods

A telephone-based cross-sectional survey was conducted between January and May 2017 in a probability sample of adults who were members of the Norwegian Association of the Blind and Partially Sighted. Participants were asked questions about their sociodemographic characteristics, characteristics of vision loss, general self-efficacy (General Self-efficacy Scale), and life satisfaction (Cantril’s Ladder of Life Satisfaction). We obtained norm data from a representative survey of the general Norwegian population (N = 1792; mean age 53.2 years; 52.5% females).

Results

People with visual impairment had higher levels of general self-efficacy than people in the general population (Mean: 31.5 versus 29.0, p < .001). Results from linear regression analyses of the visual impairment population showed that higher education and residential in an urban municipality were associated with higher self-efficacy. Having additional impairments and a previous history of physical or sexual assaults were associated with lower self-efficacy. A linear dose-response relationship was found between self-efficacy and life satisfaction, in the visual impairment population as well as in the general population.

Conclusions

People with visual impairment have higher self-efficacy than people in the general population, possibly due to extensive mastery experience in how to handle life as visually impaired. Self-efficacy seems to be important in achieving the best possible life.
Identifying factors that nurses consider in the decision-making process related to patient care during the COVID-19 pandemic
Authors: Anton Nicholas , Hornbeck Tera , Modlin Susan , Haque Md Munirul , Crites Megan , Yu Denny
Published: July 2021

Background

Nurse identification of patient deterioration is critical, particularly during the COVID-19 pandemic, as patients can deteriorate quickly. While the literature has shown that nurses rely on intuition to make decisions, there is limited information on what sources of data experienced nurses utilize to inform their intuition. The objectives of this study were to identify sources of data that inform nurse decision-making related to recognition of deteriorating patients, and explore how COVID-19 has impacted nurse decision-making.

Methods

In this qualitative study, experienced nurses voluntarily participated in focused interviews. During focused interviews, expert nurses were asked to share descriptions of memorable patient encounters, and questions were posed to facilitate reflections on thoughts and actions that hindered or helped their decision-making. They were also asked to consider the impact of COVID-19 on nursing and decision-making. Interviews were transcribed verbatim, study team members reviewed transcripts and coded responses, and organized key findings into themes.

Results

Several themes related to decision-making were identified by the research team, including: identifying patient care needs, workload management, and reflecting on missed care opportunities to inform learning. Participants (n = 10) also indicated that COVID-19 presented a number of unique barriers to nurse decision-making.

Conclusions

Findings from this study indicate that experienced nurses utilize several sources of information to inform their intuition. It is apparent that the demands on nurses in response to pandemics are heightened. Decision-making themes drawn from participants’ experiences can to assist nurse educators for training nursing students on decision-making for deteriorating patients and how to manage the potential barriers (e.g., resource constraints, lack of family) associated with caring for patients during these challenging times prior to encountering these issues in the clinical environment. Nurse practice can utilize these findings to increase awareness among experienced nurses on recognizing how pandemic situations can impact to their decision-making capability.
Vulnerability of Pacific salmon to invasion of northern pike (Esox lucius) in Southcentral Alaska
Authors: Jalbert Chase S. , Falke Jeffrey A. , López J. Andrés , Dunker Kristine J. , Sepulveda Adam J. , Westley Peter A. H.
Published: July 2021

The relentless role of invasive species in the extinction of native biota requires predictions of ecosystem vulnerability to inform proactive management strategies. The worldwide invasion and range expansion of predatory northern pike (Esox lucius) has been linked to the decline of native fishes and tools are needed to predict the vulnerability of habitats to invasion over broad geographic scales. To address this need, we coupled an intrinsic potential habitat modelling approach with a Bayesian network to evaluate the vulnerability of five culturally and economically vital species of Pacific salmon (Oncorhynchusspp.) to invasion by northern pike. This study was conducted along 22,875 stream km in the Southcentral region of Alaska, USA. Pink salmon (O.gorbuscha) were the most vulnerable species, with 15.2% (2,458 km) of their calculated extent identified as “highly” vulnerable, followed closely by chum salmon (O.keta, 14.8%; 2,557 km) and coho salmon (O.kisutch, 14.7%; 2,536 km). Moreover, all five Pacific salmon species were highly vulnerable in 1,001 stream km of shared habitat. This simple to implement, adaptable, and cost-effective framework will allow prioritizing habitats for early detection and monitoring of invading northern pike.
Viral and immunological markers of HIV-associated Kaposi sarcoma recurrence
Authors: Ngalamika Owen , Mukasine Marie Claire , Kawimbe Musonda , Vally Faheema
Published: July 2021

Kaposi sarcoma (KS) is an AIDS-defining angio-proliferative malignancy highly prevalent in Sub-Saharan Africa. The main objective of this study was to determine the factors associated with recurrence of HIV-associated KS. We recruited a cohort of individuals on antiretroviral therapy who were in remission for HIV-associated KS after undergoing cytotoxic cancer chemotherapy. Collected variables included sociodemographic and clinical parameters, cytokines and chemokines, HIV viral loads, and CD4 counts. Compared to individuals who had KS recurrence, IL-5 was significantly higher at time of follow-up in individuals who had sustained remission (22.7pg/mlvs. 2.4pg/ml; p = 0.02); IL-6 was significantly higher at baseline and time of follow-up in individuals who had sustained remission, (18.4pg/mlvs. 0pg/ml; p = 0.01) and (18.0pg/mlvs. 0.18pg/ml; p = 0.03) respectively; IP-10 was significantly lower at baseline and at time of follow-up in individuals who had sustained remission, (534pg/mlvs. 920pg/ml; p = 0.04) and (446pg/mlvs.1098pg/ml; p = 0.01) respectively; while HIV viral load was significantly lower at baseline and at time of follow-up in individuals who had sustained remission, (0copies/mlvs. 113copies/ml; p = 0.004) and (0copies/mlvs. 152copies/ml; p = 0.025) respectively. Plasma levels of IL-5, IL-6, and IP-10 are associated with recurrence of HIV-associated KS, while persistently detectable HIV viral loads increase the risk of KS recurrence.
Mulheres “arteiras” tecendo potência
Authors: Godoi Stela Cristina de , Santos Iara Teixeira Rebouças dos , Jordão Jaqueline
Published: July 2021

Este escrito baseia-se na observação participante obtida pela prática extensionista, junto ao grupo de mulheres “Guerreiras do Satélite”, assistidas pelo CRAS Satélite Íris, no município de Campinas-SP. O projeto que subsidia essa reflexão desenvolve atividades socioeducativas, visando contribuir para o fortalecimento das mulheres e de seus vínculos sociais. As ações são pensadas como estratégias para o enfrentamento do insulamento das mulheres que resulta da desigualdade na divisão sexual do trabalho. Observamos que o recrutamento prematuro das meninas para os trabalhos reprodutivos, o abandono escolar e a violência doméstica privam as mulheres de ocupar espaços sociais fora do núcleo familiar. Neste sentido, as intervenções utilizam Círculos de Cultura, baseados na perspectiva freiriana de educação como prática de comunhão e liberdade, e Círculos de Trabalho Artístico, que concebe a educação como esforços conativos do corpo-mente social em sua busca por preservar-se e atualizar o bem comum. Por meio da atividade problematizadora e de reconstrução imaginativa que culminam na produção artística, buscamos ressignificar o sofrimento, despertar as paixões alegres e fortalecer um devir ético que encorajem essas mulheres a perseverar em si próprias, tecer laços de solidariedade e ocupar outros espaços sociais não prescritos pelas estruturas vigentes.
Extensão universitária
Authors: Azevedo Ana Paula Zaikievicz , Modolo Ana Karina , Silva Lilliam May Grespan Estodutto da
Published: July 2021

Este trabalho objetiva compartilhar as experiências desenvolvidas em um projeto de extensão interdisciplinar, o qual envolve docentes e acadêmicos dos cursos de graduação em Farmácia, Nutrição, Ciências Biológicas e Pedagogia, na Universidade Católica Dom Bosco, em Campo Grande-MS. Denominado “Estratégias para Educação e Saúde da Criança”, o projeto tem como principal objetivo desenvolver, por meio de ações lúdicas e formativas, a promoção da saúde e bem-estar de crianças de até 12 anos de idade. O projeto foi criado em 2004 e durante o ano de 2019 atendeu quatro instituições, sendo uma escola de educação infantil da rede pública, duas escolas da rede privada e um projeto social, no qual são atendidas crianças e mulheres em situação de vulnerabilidade. O desenvolvimento do projeto tem possibilitado ampliar a formação acadêmica e pessoal dos acadêmicos e docentes envolvidos nas ações, além de contribuir com as instituições atendidas, possibilitando às crianças, professores, pais e familiares das crianças que frequentam as quatro instituições atendidas, acesso a informações, desenvolvimento de ações e atividades que possibilitam melhores condições de vida e bem-estar.
Ação multiplicadora
Authors: Silva Fernanda Costa , Gondim Isadora Oliveira , Soares Sonia Maria
Published: July 2021

Este relato de experiência tem como objetivo descrever as ações e metodologias adotadas pelo projeto de extensão universitária “Ação multiplicadora: uma proposta de inclusão social e acessibilidade”, anos 2018 e 2019. As principais metodologias adotadas para o desenvolvimento das ações do projeto foram: pesquisa bibliográfica, entrevistas, preparação de materiais didáticos, seminários, exposições, observação e análise fílmica. O projeto contribuiu para ampliar as discussões acerca da inclusão social e acessibilidade das pessoas com deficiência e conscientizar atores sobre a necessidade de propiciar ambientes inclusivos, de socialização e acessíveis. Concluiu-se que o fortalecimento de projetos dessa natureza promove a reflexão da comunidade universitária e auxilia o processo de inclusão social e acessibilidade das pessoas com deficiência nas Instituições Federais de Ensino Superior.
Práticas de extensão no ensino de Jornalismo
Authors: Ferreira Mayara Sousa , Costa Ruthy Manuella de Brito
Published: July 2021

A formação acadêmica tem como base o ensino, a pesquisa e a extensão, que precisam ocorrer de maneira coordenada, visando uma formação que contemple teoria, prática, bem como investigação científica. No curso de Jornalismo, atividades de extensão oportunizam aos estudantes práticas que se aproximam daquelas que se dão na ambiência profissional. Sendo assim, o presente trabalho tem como objetivo descrever a experiência do projeto de extensão do referido curso na Faculdade R. Sá, a partir da perspectiva da produção de notícias, pesquisa documental e produção fotográfica, através da revista Das Antigas. Com uma abordagem qualitativa, a construção deste trabalho se deu com base em pesquisa documental e de campo. Teoricamente, o trabalho se ampara principalmente em Duarte (2012), Goulart (2004) e Sousa (2004). Os resultados evidenciam a importância e a necessidade do aprimoramento das práticas extensionistas interdisciplinares para formação do jornalista. Além disso, é uma forma de relacionar ambiente acadêmico com a sociedade.
Exposição itinerante de Física
Authors: Silva João Marcus Neres da , Santos Adevailton Bernardo dos
Published: July 2021

Este texto apresenta o desenvolvimento, a aplicação e os resultados de uma atividade de extensão a partir de uma Exposição Itinerante de Física. O objetivo é discutir como uma exposição de experimentos relacionados à disciplina de Física contribui para a motivação dos estudantes de Ensino Médio. O desenvolvimento desse trabalho está associado a um projeto de extensão que visa contribuir com o ensino básico de Física por meio da criação de um espaço lúdico e interativo que pudesse ser levado a diversos ambientes, além de uma pesquisa sobre possíveis impactos gerados pela atividade com experimentos. Preliminarmente, a Exposição Itinerante de Física foi levada a duas escolas da cidade de Janaúba, Minas Gerais, onde as atividades experimentais foram realizadas e os alunos foram convidados a responder questionários de opinião antes e após as intervenções. As análises dos resultados indicam que atividades desse tipo podem interferir positivamente sobre o desenvolvimento da autonomia, a sensação de competência e o estabelecimento de vínculos nos estudantes, que são fatores relacionados à motivação intrínseca, revelando que a proposta pode ter efeitos relevantes sobre os estudantes.
The Effect of Funding Policy, Investment Policy, and Dividend Policy on the Firm Value through Good Corporate Governance as an Intervening Variable
Authors: Sulhan Muhammad , Purnamasari Puji Endah
Published: July 2021

The company’s main objective is maximizing the firm value which means it increases shareholder prosperity. This can be achieved by combining funding policy, investment policy, and dividend policy optimally. The application of good corporate governance (GCG) is used to direct and control the company to be able to run the company’s operations following stakeholder’s expectations. This study aims to determine the influence of funding policies, investment policies, and dividend policies on firm value by using GCG as a mediating variable.This study uses a quantitative approach. In this study, the population is all companies listed in the banking sub-sector on the Indonesia Stock Exchange in 2013-2017, with a total of 43 companies. The samples are taken by purposive sampling technique with 12 companies. The method of data analysis used in this study was descriptive analysis and path analysis using Partial Least Square (SmartPLS3).The result of the study shows that the investment policy has a positive effect on firm value. The funding policy and dividend policy do not affect firm value. While investment policy has a positive effect on GCG. Furthermore, the funding policy and dividend policy do not affect GCG. GCG successfully mediates the relationship of investment policy with the firm value. That is, the higher profitability will affect the GCG so that it will affect the firm value. However, GCG as an intervening variable does not succeed in mediating the relationship of funding policy and dividend policy with the firm value.
Comparative Performance of New Surface Roughness Element and Pin fin in Converging Channel for Gas Turbine Application
Authors: Gaur Ritesh , Ganesan S. , Prasad B.V.S.S.S.
Published: July 2021

Thermal performance of a novel surface roughness element, named as Double 45 Dimple (D45D), is compared with pin-fin element in a converging channel with rectangular cross section and presented. The Surface Roughness Element (SRE) is derived by combining protrusion & dimple in a particular fashion such that area available for transfer of heat increases. The objective of this study is to demonstrate the applicability of D45D element channel for trailing edge channel of a typical nozzle guide vane where typically pin-fin element is used. New cooling configuration of Nozzle Guide Vane (NGV) with D45D element is also proposed. All thermal and flow related results are derived using validated CFD approach with EARSM turbulence model for a typical value of Reynolds number. From this investigation, it is found that D45D element provides remarkable improvement in the averaged as well as heat transfer in local region for the corresponding surface which makes it a candidate for trailing edge channel cooling application.
Degradation of Mononitrotoluene by Electrochemical Method
Authors: Kumar Ratanesh , Wagh Pratap Baburao , Ingale Sanjay Vishwasrao , Joshi K D
Published: July 2021

Present paper deals with studies on the degradation of Mononitrotoluene (MNT) by electrochemical method. The Electro-Fenton and Electro-Peroxide methods are explored to degrade MNT upto its drain discharge limit of 1 ppm. Effects of some important parameters which ultimately decide the rate of degradation of MNT viz. oxidizer, pH, catalyst and voltage etc. have been critically studied. The detailed studies have been carried out which includes variation in different parameters viz. pH from acidic range to basic range, catalyst concentration from 10 ppm to 50 ppm, Oxidizer concentration from 5 mM to 40 mM and potential across electrodes from 4 V to 24 V for efficient degradation of MNT. It is observed that optimised values of precursors viz. catalyst (FeSO4 ) concentration of 40 ppm, pH of 3, potential across electrodes of 12V and oxidizer (H2 O2 ) concentration of 25 mM; Electro-Fenton reaction has been carried out to degrade 50 ppm MNT solution up to its drain discharge limit of 1 ppm and on other hand under Electro-Peroxide reaction results in degradation of MNT from 50 ppm to 12 ppm. The comparative studies of Electro-Fenton and Electro-Peroxide reactions have been carried out for MNT solution and the treated solution has been characterised by using UV-Visible spectrophotometer and Total Organic Carbon (TOC) analyzer and the obtained data on MNT effluent studies may be applicable to explore the efficient mineralisation of 2-Methyl-1, 3, 5-trinitrobenzene effluent. The observed results have been interpreted and reported in the present study.
Tourism Business in a VUCA World: Marketing and Management Implications
Authors: LUBOWIECKI-VIKUK Adrian , SOUSA Bruno
Published: July 2021

In the context of modern management, we referred to the re-creation of tourism products, modification of segments, and directions of marketing tourism enterprises and destinations development. The COVID-19 crisis should thus be seen as an opportunity to critically reconsider tourism’s growth trajectory, and to question the logic of more arrivals implying greater benefits. As a result of the COVID-19 pandemic, the tourism industry went from over-tourism to ‘no tourism’. We paid attention to the implementation of the EFE concept (education, flexibility, empathy) and the necessary marketing segmentation. This manuscript aims to further develop the understanding of the marketing involvement for tourism business in a volatile, uncertain, complex, and ambiguous (VUCA) world. Implications for future research are also presented.
Tourism Development and Frequency of Nationalities in Kosovo Tourism
Authors: MILLAKU Bedri , DRESHAJ Adem , ELEZAJ Elvis , KUQI Bekë
Published: July 2021

Tourism is one of the most important branches of society in many countries of the world. Today its development has taken an important impetus for the development of many societies which really accept tourism as a very important economic activity. Many places have changed the physiognomy of the landscape, giving importance to the development of this activity. It can rightly be said that many countries have received the epithet of developed countries because of the tourist destinations they have. In this way, the Republic of Kosovo, even though it is a young state, has at its disposal important potential values which really represent a tourist attraction. Although they are still in the process of developing and improving tourism which will be in function of the successful tourist offer. In order to develop successful tourism offers, potential values must be made available which will be used as a tourist attraction which is available for tourism development. And with this the overall economic development which affects the overall development of the country. The Republic of Kosovo has potential values which are useful for the development of the tourism product. This is best reflected around Rugova, respectively in Boge where we have a large frequency of different nationalities of tourists.
Urgensity of “Halal Tourism”: Religiosity, Awareness, and Interest from Stakeholders
Authors: ZARKASYI Muhammad Ridlo , KURNIAWAN Dhika Amalia , DARMA Dio Caisar
Published: July 2021

The push for the “halal tourism’ attribute in Muslim countries is quite enthusiastic. There are great interest and encouragement from tourists. Explicitly, currently, several regions in Indonesia such as Ponorogo Regency are trying to realize this concept. In this paper, we have the ambition to see how much influence “halal tourism’ has in Ponorogo Regency. Through variable boundaries, the relationship between religiosity, awareness, and interest can be found. This study attempt to reach all stakeholders who are already involved in the tourism sector. The survey approach was carried out by open interviews, where data was collected based on 409 informants. A multiple linear regression model is applied to answer the hypothesis design empirically. As a result, the informants who are divided into 5 groups who have experience in the field of tourism consider the concept of ‘halal tourism’ quite urgent to be revitalized. Other analyzes also found that religiosity and awareness had a significant effect on interest (p <0.05). Awareness plays an important role in the relationship between religiosity and interests. The originality of this invention lies in the elements (variables and items) used, therefore it deserves to be used as a reference at a later date by decision-makers.
Physical and Ecological Carrying Capacity for Cave Tourism Management
Authors: CHEABLAM Onanong , RATTANARAT Jantira
Published: July 2021

Cave tourism is a nature-based tourism which has recently gained its popularity in Thailand. Cave sare natural attractions which are extremely vulnerable, especially caves with limitations in both size and area. Thus, this study aims at studying and determining the maximum and suitable carrying capacity to support physical and ecological tourism in Ban Tham Sua tourism community area to avoid overtourism. The methodology used in this research was a survey on the tourist’s utilization, duration, number of tourists, and tourism impacts. Moreover, the impact assessment using 16 indicators presented by 5 geological experts for ecological carrying capacity of the cave areas were also conducted. This area-based study was conducted in 3 areas: Thep Nimit Cave, Nang Fa Cave, and Sua Noi Cave. The study found that the number of tourists in these three caves were below carrying capacitywhich had no or insignificant impact on natural resources. However, it was found that SuaNoi Cave was a huge destruction of the original resources. The study suggests that carrying capacity of cave tourism should be well planned and managed to prevent the environmental degradation.
Consumer Brand Engagement and Brand Communications on Destination Brand Equity Maritine Tourism in Indonesia
Authors: MANSUR Suraya , SARAGIH Nurhayani , SUSILAWATI Siti , UDUD Yusiatie , ENDRI Endri
Published: July 2021

This study aimed to understand the influence of consumer-brand engagement and brand communication on destination brand equity, survey to maritime tourism of Ujung Kulon and Anak Krakatau, Banten. The population chosen in this study is the Instagram followers of Ujung Kulon and Krakatau Banten.The total of the samples are 96 respondents chosen using purposive sampling. This study used inferential statistic tests, which were divided into two: The correlation Test and Linear Regression Test. This study used a correlational survey method Approach. This research used a quantitative approach and a positivist paradigm. The results showed that the use of Instagram is successful in creating destination brand equity because the entertainment and interaction dimension provided a strong effect on the loyalty dimension of the destination brand equity variable. People who are online and following the Instagram account became loyal because the pictures posted gave entertainment value, joy, and relaxation effect. The interaction between the followers and admin of the account of Maritime Tourism of Ujung Kulon and Anak Krakatau, Banten also added the entertainment value. This study provides new contributions regarding the promotion of maritime tourism destinations through theories about brand engagement, brand equity, and brand communication.
DETERMINAN MATRIKS CENTROSYMMETRIC BENTUK KHUSUS ORDO 4×4 BERPANGKAT BILANGAN BULAT POSITIF
Authors: Rahma Ade Novia , Erizona Esty , Rahmawati Rahmawati
Published: July 2021

Penelitan ini bertujuan untuk menentukan determinan dari suatu matriks centrosymmetric bentuk khusus ordo  berpangkat bilangan bulat positif. Dalam menentukan determinan matriks centrosymmetric bentuk khusus terdapat beberapa langkah yang perlu dikerjakan. Pertama perhatikan bentuk pola matriks centrosymmetric bentuk khusus  sampai  sehingga didapat bentuk umumnya kemudian dibuktikan dengan induksi matematika. Kedua perhatikan bentuk pola determinan matriks centrosymmetric bentuk khusus  sampai  sehingga didapat bentuk umumnya lalu dibuktikan dengan pembuktian langsung. Hasil akhir dalam penelitian ini diperoleh bentuk umum matriks, determinan dari matriks centrosymmetric berpangkat bilangan bulat positif dengan  ganjil dan  genap.
Instruments to Measure Health Literacy among Children: A Scoping Review
Authors: Abdillah Ina Laela , Lusmilasari Lely , Hartini Sri
Published: July 2021

Background: Research related to health literacy among children is limited due to the lack of appropriate measurement tools for this population. The measurement tools used to measure health literacy among children are usually adapted from the adult versions. Researches related to instruments measuring health literacy that can be used for children in school environments are inadequate. This study aimed to synthesize research on the instruments that measure health literacy among children in the community setting. Method: We carried out a scoping review to synthesize research on the instruments measuring health literacy among children in the community setting. The article searching process was targeted to collect articles with corresponding populations, concepts, and contexts. The search was conducted through PubMed, ProQuest, ScienceDirect, and Sage Journals databases published between 2010- 2020. The selection process was done using Preferred Reporting Items for Systematic Reviews and Meta-Analyses methods (PRISMA). The following critical appraisal used The Joanna Briggs Institute checklist. Results: Out of 328 studies, six articles were selected for this review. Consensus showed that health literacy needs to be applied in various situations. Improving the health literacy of children in the early stages is crucial for children's development and personal health. Several instruments can be applied to measure health literacy in school-age children, such as Health Literacy Measures for Adolescents, Health Literacy for School-aged Children in the English, Turkish and Lithuanian versions, and Chinese version of the eight-item Health Literacy Assessment Tool. Generally, the instruments are adequate, while only two instruments in this study are inadequate because they do not describe the validity and reliability.