bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Dietary Zinc Alginate Complex Supplementation on Growth Performance, Nutrient Utilisation ,Tibia bone characteristics, Ileum morphology, Carcass characteristics, Meat quality and Footpad Health in Broiler Chicken
Authors: Selvapandian Sridhar , N Muthusamy , C Kathirvelan , G Kumaresan , P Vasanthakumar , R.P Senthilkumar
Published: September 2024

A biological trial was carried out with 256 numbers of sex-separated day-old broiler chicks distributed to four experimental groups with eight replicates, each replicate consisting of eight chicks. The experimental basal diet supplemented with zinc oxide (T1) at 80 ppm and three levels of zinc alginate complex at 56,45 and 34 ppm were designated as dietary treatments (T2, T3 and T4). At the end of 35 days T4, T3 and T2 groups had significantly (P < 0.01) higher body weight and FCR compared to the zinc oxide group and average daily feed intake (g/bird) was comparable among the zinc alginate complex groups and the zinc oxide-supplemented group. The tibial zinc was significantly (P < 0.01) increased with a low level of inclusion of zinc alginate complex compared to the zinc oxide group. However, serum zinc was not statistically significant, but the lower inclusion of zinc alginate complex at 34 ppm had numerically higher serum zinc concentration than the zinc oxide group. The zinc alginate complex at 34 ppm and 56 ppm significantly (P < 0.05) increased the dry matter digestibility and crude protein digestibility. At 34 ppm and 45 ppm significantly (P > 0.05) increased tibial bone length. The ileal villi height and ileal villi height to crypt depth ratio (VH: CD) were significantly (P < 0.01) increased in the zinc alginate complex. Overall, these findings underscore the potential benefits of zinc alginate complex in enhancing nutrient utilization, and growth performance in poultry farming.
Unexpected Winners of Climate Change: The Rise of Mosses
Authors: ERATA Hüseyin , KIRAÇ Akın , BATAN Nevzat
Published: September 2024

This study investigates the impact of climate change on the geographic distribution and ecological roles of terrestrial mosses. Given their remarkable adaptability, we anticipate that climate change will enable terrestrial mosses to expand across a wider geographic range. Mosses possess a remarkable ability to withstand dehydration and quickly resume the process of photosynthesis, which allows them to thrive and adapt effectively in the face of fluctuating climatic conditions. Mosses also have a significant impact on ecosystem equilibrium. Their crucial function in the global carbon cycle is defined by their ability to sequester carbon, particularly in places dominated by mosses such as peatlands. This study demonstrates that land mosses have the capacity to fulfill a crucial function in maintaining ecosystem sustainability and managing carbon levels in the face of climate change. Mosses could potentially restore the vigor and variety lost due to climate change, thereby restoring everything to its previous state.
Logbucharbeit in Lernbüros
Authors: Waldner Norbert
Published: September 2024

Individualisierte Lernsettings finden immer häufiger Einsatz in Schulen und lösen herkömmliche lehrerzentrierte Unterrichtskonzepte ab. Lernbüros, in denen mit Logbüchern gearbeitet wird, stellen einen möglichen Schritt in diese Richtung dar. Doch wie erfolgreich ist dieser Ansatz, wo gibt es Verbesserungsmöglichkeiten und wie sieht dabei die neue Rolle der Lehrpersonen aus?
TRANSFORMATION OF MEDICAL RESEARCH DUE TO AND BEYOND THE COVID-19 PANDEMIC
Authors: Dewi Kristin Purnama
Published: September 2024

The COVID-19 pandemic has significantly altered various sectors, and the scientific community is no exception. It has reshaped the research landscape across numerous disciplines, profoundly impacting how medical research is conducted, prioritized, and funded. As we move into the post-pandemic world, understanding these transformations is crucial for evaluating shifts in medical research and contemplating their implications for future scientific inquiry. This editorial focuses on the pandemic-driven transformations in medical research, including methodological innovations, changes in research focus, and their implications for future research directions.
The need to respond rapidly to a rapidly changing environment has accelerated the adoption of digital technologies and remote research methodologies. During lockdowns and periods of social distancing, the continuation of research increasingly relied on virtual collaboration and online data collection. This shift has highlighted how digital technologies can enhance research efficiency and brought attention to the necessity of robust frameworks to address the challenges associated with virtual interactions and remote data collection.
The effectiveness of biotin in therapy alopecia of various origins, pathologies of the skin and nails
Authors: Torshin I. Yu. , Gromova O. A.
Published: September 2024

Biotin deficiency is caused by inflammatory bowel diseases that impair the absorption of the vitamin, special dietary disorders with the consumption of raw eggs (excess avidin – a vitamin B7 blocker protein), magnesium deficiency, smoking, alcohol, treatment with broad-spectrum antibiotics, sulfonamides, and anticonvulsants. Hypovitaminosis B7 has also been noted in individuals with congenital genetic defects of the biotinidase gene or other genes involved in biotin metabolism. Deficiency of water-soluble vitamin B7 (vitamin H) – manifested by dry skin, seborrheic dermatitis, dermatitis around the eyes, nose, mouth, ears and groin, impaired nail growth, slow healing of skin cuts, atopic dermatitis, striations, splitting, brittle nails and alopecia (diffuse and androgenic form). Alopecia occurs when hair follicles die and leads to hair loss. The human proteome contains 51 proteins involved in biotin metabolism. In particular, D-biotin-dependent carboxylases play an important role in the metabolism of fatty acids, amino acids, carbohydrates, cell division and growth, incl. keratinocytes and hair follicle cells. The molecular mechanisms of the effects of D-biotin on the skin and its appendages may involve various growth factors: regulation of the signaling pathways of growth factors (IGF-1, FGF, KGF, HGF, VEGF, SIRT-1, Wnt and beta-catenin) has been shown. Hair follicle stem cells cause the cyclical growth of hair follicles. Growth factors are involved in the activation of stem cell growth by D-biotin; activation of the Wnt/β-catenin signaling cascade leads to the activation of cyclin D1 proteins (initiates DNA synthesis and leads to increased viability of hair follicles. The results of fundamental and clinical studies confirm the prospects of using biotin in dermatology for the treatment of diseases of the skin, hair and nails, incl. alopecia of various origins (androgenic, focal, diffuse). The results of the studies indicated that biotin was well tolerated, and there was no risk of hypervitaminosis even when taking megadoses (hundreds of milligrams).
Evolution characteristics and attribution analysis of runoff in the coal mining area in northwest China: A case study of the Kuye River Basin
Authors: Zhang Zhiqiang , Chen Liying , Zhang Fawang , Qian Jiazhong , Feng Yuqing , Han Shuangbao , Dai Fenggang
Published: September 2024

The Kuye River Basin is the main coal-producing area in northwest China, and it is also a typical arid and semi-arid area. Under the combined influence of climate change and human activities, the runoff of the basin decreases noticeably. The Mann–Kendall trend test, the Hurst index, cumulative anomaly, and wavelet analysis were used to analyze the runoff evolution characteristics of the Kuye River, and the contributions of climate change and human activities to the runoff reduction were quantitatively separated by the slope-changing ratio of the cumulative quantity. The results showed that the runoff decreased significantly from 1970 to 2020, and there was an obvious abrupt change in 1996, while the change trends in precipitation and evaporation were not significant. The contributions of climate change and human activities to runoff reduction were 22.71 and 77.29%, respectively, and human activities have become the dominant factor in runoff variations. Coal mining and the implementation of soil and water conservation measures are considered to be the main human activities contributing to the reduction in runoff. In particular, mining activities reduce groundwater recharge to rivers, which provides a profound understanding of the effect of human activities in mining areas on runoff variation.
Contribuições da terapia cognitivo comportamental no tratamento de mulheres com transtorno de compulsão alimentar periódica.
Authors: De Souza e Silva Marinho Layla , Aparecida Gomes Almeida Stéphani , Siqueira de Moraes Mesquita Vitor
Published: September 2024

A ansiedade patológica pode gerar prejuízos emocionais e causar perdas na qualidade de vida tendo grande influência para o surgimento do Transtorno de Compulsão Alimentar Periódica (TCAP) que afeta diferentes tipos de pessoas, independente da faixa etária e sexo. Os estudos mostram que as mulheres ainda são mais vulneráveis de desenvolverem os transtornos alimentares por causa de fatores como a influência da mídia e pressão por um ideal social de magreza. O objetivo desse estudo foi identificar as contribuições da Terapia Cognitivo Comportamental (TCC) no tratamento de mulheres com TCAP. Foi adotado como metodologia a pesquisa bibliográfica. Observou-se que o TCAP é multifatorial e que a ansiedade patológica pode exercer grande influência no desenvolvimento do transtorno. Uma das possibilidades de tratamento psicológico para o transtorno é a TCC que vem sendo considerada a abordagem mais utilizada e eficaz para a diminuição dos sintomas dos transtornos alimentares, entre eles, o TCAP.
Estresse laboral em servidores de vigilância em instituições de ensino superior federal
Authors: Gomes Valter Gomes , José Lopes Agnaldo
Published: September 2024

Estresse ocupacional é uma manifestação evidente em diversos segmentos profissionais e, entre profissionais de segurança, há uma predominância relevante. O objetivo desta revisão foi o de analisar o nível de estresse laboral em servidores de vigilância em instituições de ensino superior federal. A metodologia utilizada foi o da revisão integrativa de literatura por meio de consultas a materiais já publicados entre os anos de 2018 a 2023 e disponibilizados nas bases de dados da Scielo e PubMed. Conforme se pode compreender das informações descritas nesta revisão, embora haja deficiência acerca do objeto pretendido analisar, por analogia, é possível mencionar que os servidores de vigilância são suscetíveis à níveis elevados de estresse em instituições de ensino federal, em decorrência, principalmente, da natureza do trabalho, cujos fatores predisponentes estão associados às altas demandas de serviços, carga horária, conflito/incerteza, prevenção de ameaças e qualidade de clima organizacional. Tais condições implicam em prejuízo psicológico como depressão e ansiedade, bem como físicos com incidência de obesidade, diabetes, hipertensão e doenças cardiovasculares. Considerando que a profissão de segurança vem crescendo na última década, é fundamental o desenvolvimento de uma proposta de intervenção da medicina ocupacional, bem como a notificação de manifestações associadas ao estresse ocupacional, a fim de monitorar as patologias associadas a esta condição.
Ferritin Hinders Ferroptosis in Non-Tumorous Diseases: Regulatory Mechanisms and Potential Consequences
Authors: Xie Zhongcheng , Hou Qin , He Yinling , Xie Yushu , Mo Qinger , Wang Ziyi , Zhao Ziye , Chen Xi , Peng Tianhong , Li Liang , Xie Wei
Published: September 2024

Ferritin, as an iron storage protein, has the potential to inhibit ferroptosis by reducing
excess intracellular free iron concentrations and lipid reactive oxygen species (ROS). An insufficient
amount of ferritin is one of the conditions that can lead to ferroptosis through the Fenton reaction
mediated by ferrous iron. Consequently, upregulation of ferritin at the transcriptional or
posttranscriptional level may inhibit ferroptosis. In this review, we have discussed the essential
role of ferritin in ferroptosis and the regulatory mechanism of ferroptosis in ferritin-deficient individuals.
The description of the regulatory factors governing ferritin and its properties in regulating
ferroptosis as underlying mechanisms for the pathologies of diseases will allow potential therapeutic
approaches to be developed.
Diet-induced Obesity: Pathophysiology, Consequences and Target Specific Therapeutic Strategies
Authors: Banerjee Munmun , Pandey Veda P.
Published: September 2024

Diet has emerged as a pivotal factor in the current time for diet-induced obesity (DIO).
A diet overloaded with fats and carbohydrates and unhealthy dietary habits contribute to the development
of DIO through several mechanisms. The prominent ones include the transition of normal
gut microbiota to obese microbiota, under-expression of AMPK, and abnormally high levels of
adipogenesis. DIO is the root of many diseases. The present review deals with various aspects of
DIO and its target proteins that can be specifically used for its treatment. Also, the currently available
treatment strategies have been explored. It was found that the expression of five proteins,
namely, PPARγ, FTO, CDK4, 14-3-3 ζ protein, and Galectin-1, is upregulated in DIO. They can
be used as potential targets for drug-designing studies. Thus, with these targets, the treatment strategy
for DIO using natural bioactive compounds can be a safer alternative to medications and bariatric
surgeries.
An Efficient and Cost-effective Modified Carbon Paste Electrodes for Diltiazem Hydrochloride Determination in Tablets
Authors: EL-Sanafery Safa S. , Elshafei Mostafa F. , Khalf Alla Perihan A. , Mohamed Gehad Genidy
Published: September 2024

Background and Objective:

This study presented new sensitive and selective modified
carbon paste (MCPE) potentiometric sensors modified with different ion pairs for the determination
of the antihypertensive drug diltiazem hydrochloride (DTM-HCl) in biological fluids, pharmaceutical
preparations, and in its pure form.

Methods:

Plasticizers, ion pair type, ion pair content, response time, temperature, and pH were just a
few of the experimental factors evaluated that were found to affect electrode efficiency. The two
electrodes that show the best sensitivity were prepared by mixing diltiazem-tetraphenyl borate
(DTM-TPB) ion pair, graphite, and TCP or o-NPOE as a plasticizer.

Result:

Over the concentration ranges of 1.0x10-5–1.0x10-2, the produced electrodes I and II demonstrated
monovalent Nernstian responses of 55.7±0.902 and 57.6±0.451 mV decade-1. The selectivity
property of the suggested electrodes was used to study the interference ions. The concentration of
DTM-HCl in pharmaceutical formulations and biological fluids was measured using these modified
electrodes. During the validation procedure, metrics like linearity, accuracy, precision, limit of detection,
limit of quantification, and specificity were used.

Conclusion:

The obtained results showed good agreement with the HPLC technique as indicated by
the F and t-test values and can conclude the possibility of using this potentiometric method in the
routine analysis of DTM-HCl.
Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription
Authors: Sigler Sara , Abdel-Halim Mohammad , Fathalla Reem K. , Da Silva Luciana Madeira , Keeton Adam B. , Maxuitenko Yulia Y. , Berry Kristy L. , Zhou Gang , Engel Matthias , Abadi Ashraf H. , Piazza Gary A.
Published: September 2024

Background:

Previous studies have reported that the cGMP-specific PDE5 isozyme is overexpressed
in colon adenomas and adenocarcinomas and essential for colon cancer cell proliferation, while PDE5 selective
inhibitors (e.g., sildenafil) have been reported to have cancer chemopreventive activity.

Aim:

This study aimed to determine the anticancer activity of a novel PDE5 inhibitor, RF26, using colorectal
cancer (CRC) cells and the role of PDE5 in CRC tumor growth in vivo.

Objective:

The objective of this study was to characterize the anticancer activity of a novel celecoxib derivative,
RF26, in CRC cells previously reported to lack COX-2 inhibition but have potent PDE5 inhibitory activity.

Methods:

Anticancer activity of RF26 was studied using human CRC cell lines. Its effects on intracellular cGMP
levels, cGMP-dependent protein kinase (PKG) activity, β-catenin levels, TCF/LEF transcriptional activity, cell
cycle distribution, and apoptosis were measured. CRISPR/cas9 PDE5 knockout techniques were used to determine
if PDE5 mediates the anticancer activity of RF26 and validate PDE5 as a cancer target.

Results:

RF26 was appreciably more potent than celecoxib and sildenafil to suppress CRC cell growth and was
effective at concentrations that increased intracellular cGMP levels and activated PKG signaling. RF26 suppressed
β-catenin levels and TCF/LEF transcriptional activity and induced G1 cell cycle arrest and apoptosis
within the same concentration range. CRISPR/cas9 PDE5 knockout CRC cells displayed reduced sensitivity to
RF26, proliferated slower than parental cells, and failed to establish tumors in mice.

Conclusion:

Further evaluation of RF26 for the prevention or treatment of cancer and studying the role of PDE5
in tumorigenesis are warranted.
Anti-neoplastic Properties of Boswellic Acids and their Novel Semi-synthetic Analogs: In vitro, In vivo and Clinical Evidence
Authors: Verma Mahima , Fatima Shireen , Ansari Irfan Ahmad
Published: September 2024

Introduction:

Recently, Boswellia gum resin extract has been shown to exhibit therapeutic
properties against multiple inflammatory illnesses, comprising arthritis, asthma, diabetes, inflammatory
bowel disease, and different malignancies. There are growing shreds of evidence that Boswellia
extracts and their phytoconstituents could be used in adjuvant and combinatorial chemotherapeutic
approaches for the management and prevention of cancer.

Aim:

The principal objective of this comprehensive investigation is to offer up-to-date and in-depth
insights into the anticancer potential of boswellic acids along with their semisynthetic analog that are
novel and preventive/therapeutic substitutes for the management of cancer and inflammatory diseases
due to their strong potential.

Materials and Methods:

In the course of this review, a comprehensive compilation of In-vitro, Invivo,
and clinical evidence on the antineoplastic potential of boswellic acids was assembled through
systematic computerized searches utilizing platforms such as Google Scholar, PubMed, Sci-Hub, and
Research Gate.

Result:

Boswellic acids, the key compounds found in the resin of nearly all the species of the Boswellia
plant, have been reported to exhibit therapeutic effects by modulating various targets in different
disease conditions. Moreover, semisynthetic derivatives of boswellic acids show strong cytotoxic
effects, particularly those with cyanoenone moieties, endoperoxides, and hybrids, which exhibit enhanced
potency.

Conclusion:

In this review, we have sincerely highlighted the effectiveness of novel boswellic acids
as alternative preventive and therapeutic agents for the treatment of cancer and inflammatory conditions.
Their strong anticancer potential could provide a basis for promising future direction to develop
potent anticancer drugs for human malignancies.
Blood-Brain-Barrier (BBB) Targeting Nanoparticulate Drug Delivery Modules to Treat Cerebrovascular Disorders: Current State of the Art
Authors: Das Srilekha , Kirtania Moumita Das , Dey Sanjay , Barik Anwesha
Published: September 2024

Blood Brain Barrier (BBB) provides a protective shield for the human nervous system,
facilitating essential biochemical processes while also acting as a strong defense mechanism
against pathogens and harmful substances, including drugs. While this barrier protects the brain, it
makes it difficult to deliver therapeutics to treat cerebral diseases such as ischemia and acute arterial
thrombosis, both of which cause significant global mortality and morbidity. The urgent need
for thrombolytic agents to treat cerebral ischemia emphasizes the importance of drugs that can efficiently
penetrate the BBB. However, conventional thrombolytics have limitations due to low BBB
permeability. To overcome this barrier, various nanoparticle-based targeting strategies have been
developed. These nano-technological solutions provide advantages such as enhanced permeability,
decreased toxicity risks, and increased bioavailability when compared to other drug delivery
methods.
Kinetic Adsorption Studies of Cationic Dyes onto Molecular Sieve and Activated Carbons
Authors: Rong Lei , Tao Guanjie , He Xiaoxiao , Meng Zitian , Fathy Nady , Tao Yousheng
Published: September 2024

Background:

Dye-containing wastewater causes irreparable damage to the ecological
water system. Although adsorbents are widely used for treating wastewater containing
dyes, the comparative investigation on these materials is still insufficient for their wide
applications in the industries.

Objective:

With the aim of comparing efficient and fast adsorbent materials for cationic
dyes, we analyzed and evaluated the adsorbents of the MCM-41 molecular sieve and activated
carbons.

Methods:

The adsorption performance was studied on the common colored organics, such
as cationic dyes of rhodamine B (RhB) and methylene blue (MB) dyes. The present work
examined the impact of experimental variables, including initial dye concentration, adsorption
time, and pH, on the adsorption process and performance, as well as the adsorption
kinetics of the diverse adsorbents towards two cationic dyes.

Results:

MCM-41 molecular sieves showed relatively high adsorption capacity for RhB
and AC-2, which made their adsorption capacity for MB much higher than that of MCM-
41 molecular sieves. A comprehensive analysis was conducted using pseudo-first-order
and pseudo-second-order to decipher the mechanism of dye adsorption. The heterogeneous
adsorption mechanism could explain the dye adsorption behavior of MCM-41 molecular
sieve and activated carbons.

Conclusion:

The results demonstrated the influence of the pore structure and surface properties
of the adsorbents on the adsorption capacity of dye molecules in an aqueous solution.
For the initial concentration of cationic dye solutions of 20 mg/L, the MCM-41 molecular
sieve had a MB adsorption capacity of 130.8 mg/g under alkaline conditions at pH=10,
while the activated carbon adsorbents showed a stable MB adsorption capacity of 266.6
mg/g under different pH conditions, proving their applicability in treating wastewater containing
dyes under different acid/base environments.
Pengaruh Relationship Marketing Dan Customer Perceived Value Terhadap Repurchase Intention Dimediasi Oleh Customer Loyalty
Authors: Marpaung Putri Nauli , Arif Moh. Erfan
Published: September 2024

The objective of this study is to identify and explain the effect of relationship marketing on repurchase intention, the effect of perceived value on repurchase intention, the effect of relationship marketing on customer loyalty, the effect of perceived value on customer loyalty, the effect of customer loyalty on repurchase intention, the influence of relationship marketing on repurchase intention through customer loyalty, and the influence of perceived value on repurchase intention through customer loyalty. Using purposive sampling technique, 190 people with the minimum age of sixteen years who had bought the products of Emina more than once were selected as the respondents. The data of this explanatory research was acquired from Likert-scaled questionnaires and processed using path analysis in SPSS ver. 25. This study finds that relationship marketing does not significantly affect repurchase intention, perceived value significantly affects repurchase intention, relationship marketing significantly affects customer loyalty, perceived value significantly affects customer loyalty, customer loyalty significantly affects repurchase intention, customer loyalty mediates the effect of relationship marketing on repurchase intention, and that customer loyalty mediates the effect of perceived value on repurchase intention.
 
Abstrak
Penelitian ini bertujuan untuk mengetahui dan menjelaskan: Pengaruh relationship marketing terhadap repurchase intention, pengaruh perceived value terhadap repurchase intention, pengaruh relationship marketing terhadap customer loyalty, pengaruh perceived value terhadap customer loyalty, pengaruh customer loyalty terhadap repurchase intention, pengaruh relationship marketing terhadap repurchase intention melalui customer loyalty, dan pengaruh perceived value terhadap repurchase intention melalui customer loyalty. Penelitian ini merupakan penelitian explanatory research dengan menggunakan kuesioner bersekala likert sebagai alat pengumpulan data. Pengumpulan sampel menggunakan teknik purposive sampling dengan karakteristik responden wanita berusia > 16 tahun dan telah membeli produk Emina lebih dari satu kali. Jumlah sampel yang digunakan dalam penelitian ini adalah sebanyak 190 responden. Data yang didapat kemudian diolah menggunakan software SPSS ver.25 menggunakan analisis jalur. Hasil penelitian ini menunjukan bahwa tidak terdapat pengaruh yang signifikan relationship marketing terhadap repurchase intention, terdapat pengaruh signifikan perceived value terhadap repurchase intention, Terdapat pengaruh signifikan relationship marketing terhadap customer loyalty, Terdapat pengaruh signifikan perceived value terhadap customer loyalty, Terdapat pengaruh signifikan customer loyalty terhadap repurchase intention, Customer loyalty dapat memediasi hubungan relationship marketing dan repurchase intention, dan Customer loyalty dapat memediasi hubungan perceived value dan repurchase intention.
Pengaruh Independensi, Akuntabilitas, Profesionalisme, Dan Kecerdasan Spiritual Auditor Terhadap Kualitas Audit Pada Kantor Akuntan Publik di Bali
Authors: Ida Bagus Surya Dharma  , Mirna Amirya
Published: September 2024

Auditors in carrying out their duties, they required to produce good audit quality. Good audit quality can be produced if an auditor can show the factors that influence it. This study aims to examine the effect of auditor independence, auditor accountability, auditor professionalism, and auditor spiritual intelligence on audit quality. The population used in this study were external auditors who worked at public accounting firms in the Bali area, totaling 55 respondents. The data were taken by distributing questionnaires and this study used SPSS apps version 28 to analyze the data. The test results show that auditor independence, auditor accountability, auditor professionalism, and auditor spiritual intelligence affect audit quality.
Abstrak
Auditor dalam melaksanakan tugasnya dituntut untuk menghasilkan kualitas audit yang baik. Kualitas audit yang baik dapat dihasilkan bila seorang auditor mampu memperlihatkan faktor-faktor yang mempengaruhinya. Penelitian ini bertujuan untuk menguji pengaruh independensi auditor, akuntabilitas auditor, profesionalisme auditor dan kecerdasan spiritual auditor terhadap kualitas audit. Populasi dalam penelitian ini adalah auditor eksternal yang bekerja pada Kantor Akuntan Publik di wilayah Bali. Sampel yang diperoleh sejumlah 55 auditor. Data diambil dengan cara menyebarkan kuesioner dan penelitian ini menggunakan aplikasi SPSS versi 28 untuk mengalisis data. Hasil pengujian menunjukkan bahwa independensi auditor, akuntabilitas auditor, profesionalisme auditor, dan kecerdasan spiritual auditor berpengaruh terhadap kualitas audit
Pengaruh Leverage, Profitabilitas, Ukuran Perusahaan, Opini Audit, Audit Tenure, Dan Kualitas Auditor Terhadap Audit Report Lag
Authors: Bhagaskara Muhammad Razan Adinsa , Roekhudin
Published: September 2024

This study uses the panel data regression method to quantitatively analyze the effect of leverage, profitability, company size, audit opinion, tenure, and auditor quality on audit report lag. The samples include 90 cyclical consumer companies listed on the Indonesia Stock Exchange between 2019 and 2021. The findings of this study exhibit that, partially, leverage has an insignificant positive effect on audit report lag; profitability has a significant negative impact on audit report lag; company size has a significant positive effect on audit report lag; audit opinion has a significant negative impact on audit report lag; audit tenure has a significant negative effect on audit report lag; and auditor quality has an insignificant negative impact on audit report lag. Simultaneously, leverage, profitability, company size, audit opinion, audit tenure, and auditor quality affect audit report lag with a contribution of 15,8%.
Abstrak
Penelitian ini berupaya untuk mengetahui pengaruh leverage, profitabilitas, ukuran perusahaan, opini audit, audit tenure, dan kualitas auditor terhadap audit report lag. Jenis penelitian ini adalah penelitian kuantitatif. Penelitian ini menggunakan metode analisis regresi data panel. Adapun sampel penelitian ini adalah 90 perusahaan sektor konsumen non-primer di Bursa Efek Indonesia tahun 2019-2021. Penelitian ini menemukan bahwa secara parsial leverage berpengaruh positif namun tidak signifikan terhadap audit report lag, profitabilitas berpengaruh negatif dan signifikan terhadap audit report lag, ukuran perusahaan berpengaruh positif dan signifikan terhadap audit report lag, opini audit berpengaruh negatif dan signifikan terhadap audit report lag, audit tenure berpengaruh negatif dan signifikan terhadap audit report lag, dan kualitas auditor berpengaruh negatif namun tidak signifikan terhadap audit report lag. Secara simultan bahwa leverage, profitabilitas, ukuran perusahaan, opini audit, audit tenure, dan kualitas auditor berpengaruh terhadap audit report lag dengan kontribusi sebesar 15,8%.
Physicochemical and Organoleptic Properties of Milkfish Bonggolan (Study Proportion of Fish Meat : Sago Flour and Addition of Sodium tripolyposphate)
Authors:   Universitas Pembangunan Nasional Veteran Jawa Timur, Amaliyah Nur Azzatul , Rosida Rosida ,   Universitas Pembangunan Nasional Veteran Jawa Timur, Priyanto Anugerah Dany ,   Universitas Pembangunan Nasional Veteran Jawa Timur
Published: September 2024

Bonggolan is a fish product from the Sidayu, Gresik Regency. Bonggolan is made from a mixture of tapioca flour, fish meat, such as payus fish and spices. Bonggolan has a chewy texture with a savory taste and has a special aroma from fish. Bonggolan has a hard texture when consumed in cold condition. This change causes a decrease in consumer preference. In this study, learned about making bonggolan from milkfish meat, sago flour, and sodium tripolyposphate (STPP). The purpose of the study is to determine the effect of the proportion of fish meat : sago flour and the addition of STPP on the physicochemical and organoleptic properties of milkfish bonggolan. This study used a factorial Completely Randomized Design (CRD) with two factors. The first factor is the proportion of fish meat : sago flour (60 : 40, 50 : 50, 40 : 60). The second factor is the addition of STPP (0.0, 0.1, 0.2%). Data was analyzed using ANOVA level 5%. If there was a difference, the process continues with the DMRT Test 5%. The results of the study is the proportion of fish meat : sago flour (60 : 40) and the addition of 0.2% STPP was the milkfish bonggolan with the optimal treatment. In this treatment obtained a water content of 51.55%, ash content of 2.67%, protein content of 7.66%, fat content of 2.15%, hardness of 199.87 gf, springiness of 11.33 mm, and organoleptic tests showed the value of color 3.96 (neutral), aroma 4.24 (like), taste 4.08 (like), and texture 4.28 (like).
Enhanced Cellulose Content in Microwave-Assisted Sulfuric Acid Pretreatment of Java Grass
Authors:   Universitas Brawijaya, Cahyono Agung , Khotimah Mujaroh ,   Universitas Brawijaya, Ashabi Arman ,   University College Cork
Published: September 2024

This study investigated the enhancement of cellulose content in Java grass (Cyperus rotundus) through microwave-assisted sulfuric acid pretreatment. The research involved soaking Java grass in varying concentrations of H2SO4 (1.5%, 3%, and 4.5%) and subjecting it to microwave irradiation at 2450 MHz for different durations (25, 35, and 45 minutes). The results showed that the highest cellulose content of 43.61% was achieved with a 1.5% H2SO4 solution for 45 minutes, representing a 90.3% increase from the pre-treatment level of 22.91%. The microwave-assisted pretreatment effectively disrupted the lignocellulosic structure, reduced cellulose crystallinity, and increased biomass surface area, thereby enhancing enzymatic hydrolysis. However, an anomaly was observed in the lignin content, which increased from 14.3% to 36.65% post-treatment, likely due to errors in lignin determination and the formation of pseudo-lignin.
Sintesis dan Karakterisasi Al-MCM-41 dari Kaolin Bangka Belitung sebagai Sumber Silika dan Alumina
Authors:   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Nurfauzi Muchamad Lutfi , Susianto Mordekhai Yosep ,   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Perwitasari Dyah Suci ,   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Nugraha Reva Edra ,   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Aziz Abdul ,   Institut Teknologi Sepuluh November, Utami Diana Inas ,   Institut Teknologi Sepuluh November, Damayanti Nabilla ,   Institut Teknologi Sepuluh November
Published: September 2024

Al-MCM-41 adalah material padatan berpori yang tersusun dari silika amorf, memiliki struktur membentuk susunan heksagonal dengan ukuran pori antara 2-50 nm, sehingga dikategorikan sebagai material mesopori. Dalam pembuatan Al-MCM-41 membutuhkan sumber silika dan alumina yang tinggi sebagai bahan pembuatannya, sehingga dibutuhkan bahan yang kaya akan kedua senyawa tersebut sebagai bahan alternatif dalam pembuatan Al-MCM-41. Rumus formula kaolin adalah Al4(Si4O10)(OH)8 dengan komponen mineral utamanya adalah SiO2 dan Al2O3 Kaolin yang digunakan berasal dari bangka belitung dengan kandungan SiO2 sebesar 61% dan Al2O3 sebesar 31%, kandungan SiO2 dan Al2O3 yang cukup tinggi dimanfaatkan sebagai bahan pada sintesis material aluminosilikat seperti Al-MCM-41. Sintesis Al-MCM-41 dari kaolin dilakukan dengan metode hidrotermal. pH yang digunakan sebesar 10, dengan suhu 80°C selama 12 jam pada proses hidrotermalnya. Al-MCM-41 hasil sintesis dianalisa menggunakan XRD dan FTIR dimana pada analisa XRD sudut pendek menunjukkan 3 puncak pada 2θ= 2.237°, 3.921°, 4.449° dan XRD sudut panjang pada 2θ= 21.449°. Analisa FTIR untuk Al-MCM-41 menunjukkan pita serapan pada bilangan gelombang 436.49; 802.47; 1146.41; 1630.61; 3389.79 cm-
PERBEDAAN SUHU DAN LAMA PERENDAMAN MOCAF DENGAN MODIFIKASI ANNEALING TERHADAP SIFAT FUNGSIONAL TEKNIS DAN KANDUNGAN PATI
Authors: Ararinda Kusweni Nelfi , Subagio Achmad , Diniyah Nurud
Published: September 2024

MOCAF merupakan salah satu olahan berbahan baku ubi kayu yang difermentasi dengan mikroba. MOCAF masih memiliki beberapa kekurangan yaitu swelling power dan kelarutan yang cenderung tinggi, hal tersebut menyebabkan pemanfaatan dan pengaplikasian MOCAF pada industri pangan atau produk pangan kurang maksimal. Penelitian ini bertujuan untuk mengetahui pengaruh perbedaan suhu dan waktu annealing terhadap sifat fungsional dan kimia MOCAF termodifikasi. Metode penelitian ini menggunakan Rancangan Acak Kelompok (RAK) dengan dua faktor, masing-masing perlakuan dilakukan dua kali pengulangan. Faktor pertama suhu annealing (T) (27, 40, dan 50°C), dan faktor kedua yaitu waktu annealing (L) (0 jam (aktual 15 menit), 8 jam, 16 jam). Parameter yang diamati yaitu swelling power, kelarutan, Water Holding Capacity (WHC), Oil Holding Capacity (OHC), sineresis, kadar air, kadar abu, kadar pati, kadar amilosa, dan kadar amilopektin. Hasil penelitian menunjukkan bahwa perlakuan suhu annealing 50°C dengan waktu annealing 16 jam mampu menurunkan swelling power 17,01 (g/g), kelarutan 5,18 g/g, kadar abu 0,41%, WHC 110,79%, OHC 101,28%, sineresis 0,41%, dan amilopektin 48,16%; dan meningkatkan kadar air 10,27%, kadar amilosa 38,83%, dan kadar pati 87,88%. Modifikasi MOCAF menggunakan metode annealing dengan perlakuan perbedaan suhu dan waktu annealing berpengaruh signifikan terhadap semua parameter uji sehingga, MOCAF termodifikasi annealing dapat lebih luas dalam pemanfaatan dan pengaplikasian pada industri pangan atau produk pangan.
PENGARUH PENAMBAHAN GELATIN DAN PUREE BUAH NANGKA (Artocarpus heterophyllus) TERHADAP KARAKTERISTIK YOGHURT SUSU KAMBING
Authors: Choirun Nisa Fithri , Andini Nurhakiki Clara
Published: September 2024

Penelitian ini bertujuan untuk mengetahui pengaruh penambahan gelatin dan puree buah nangka, serta interaksinya terhadap karakteristik fisik, kimia, mikrobiologi, organoleptik dan struktur mikro yoghurt susu kambing. Penelitian ini menggunakan rancangan Acak Kelompok Faktorial (RAKF) dengan dua (2) perlakuan, yaitu konsentrasi gelatin (1%; 1,5%; dan 2%) dan konsentrasi puree nangka (5% dan 10%), dengan pengulangan sebanyak empat (4) kali. Selanjutnya, untuk mengetahui pengaruh faktor terhadap respon dilakukan analisis dengan metode ANOVA selang kepercayaan 95%. Uji lanjut dilakukan dengan metode BNJ atau DMRT selang kepercayaan 5%. Hasil analisis menunjukkan terdapat interaksi yang berpengaruh nyata antara penambahan konsentrasi gelatin dan puree nangka terhadap parameter viskositas yoghurt susu kambing. Hasil total bakteri asam laktat (BAL) tertinggi yaitu 6,3 × 107 CFU/mL. Hasil perlakuan terbaik menggunakan metode De Garmo pada sampel dengan gelatin sebesar 2% dan puree buah nangka 10% dengan nilai sineresis 0,06%; viskositas 4472,66 cp; pH 4,09; dan total asam 2,03%. Dilakukan uji kesukaan pada 101 panelis dengan parameter aroma, rasa, kekentalan, warna dan overall. Kesukaan tertinggi pada penambahan gelatin 2% dan puree buah nangka 10%. Analisis struktur mikro dilakukan pada hasil perlakuan terbaik, didapatkan struktur yang lebih kompleks dan rapat akibat penambahan gelatin dan puree buah nangka.
APROVECHAMIENTO TRADICIONAL DE LOS ANFIBIOS EN EL ESTADO DE MÉXICO
Authors: González Hernández Adriana , Santos Fita Dídac , Figueroa Serrano David , Velasco-Virrueta Viridiana , Reyes-Velázquez Erika Adriana , Avila Akerberg Victor
Published: September 2024

El conocimiento tradicional que tienen los grupos humanos sobre la fauna se está perdiendo, lo que genera la necesidad de documentar la información que poseen sobre sus recursos naturales con el fin de rescatar esos conocimientos para el manejo sustentable de los ecosistemas, ante la pérdida de especies. Por lo que el objetivo del presente trabajo fue documentar los conocimientos y prácticas tradicionales que las comunidades humanas en el Estado de México tienen acerca de los anfibios y saber si existe actualmente una relación entre la pérdida del conocimiento tradicional de los anfibios con la pérdida del recurso. Para obtener la información necesaria se aplicaron entrevistas abiertas y semiestructuradas, apoyadas por un catálogo fotográfico para identificación de las especies de anfibios. Documentamos el uso y aprovechamiento de doce especies. Los ajolotes y ranas son los anfibios más usados como medicina y alimento. Existen además criaderos de rana toro (Aquarana catesbeiana), la cual solo es comprada localmente para uso didáctico en las escuelas, los renacuajos y ranas son usados localmente para alimento y las ranas adultas se capturan y venden por encargo. Es posible que el conocimiento y las prácticas tradicionales se estén perdiendo ya sea por las actividades económicas o por la disminución en las poblaciones de anfibios debido a la contaminación y desecación de los cuerpos acuáticos.
RANGE EXTENSION AND NEW MUNICIPALITY RECORD OF Abronia taeniata (ANGUIDAE) FROM PINAL DE AMOLES, QUERÉTARO, MEXICO
Authors: Arenas-Monroy José Carlos , Cruz-Elizalde Raciel , Solano-Zavaleta Israel
Published: September 2024

We present data of a specimen which represents a new municipality record and range extension of Abronia taeniata for Pinal de Amoles, Querétaro, México. We also provide a description of the vegetation at the site, and comments on the species’ resilience to habitat perturbation. Finally, we suggest the existence of a previously undocumented large population of A. taeniata in Sierra de Pinal de Amoles based on our finding, and on several observations of the species available through a citizen science platform.
A Study on the Simulation of Fiber Bragg Grating (FBG) as a Strain Sensor
Authors: Jalil Muhammad Arif Bin
Published: September 2024

Abstract: This study models, simulates, and characterizes the Fibre Bragg grating (FBG) in terms of maximum reflectivity, bandwidth, the effect of applied strain on the wavelength shift, λB, and the wavelength shift sensitivity with strain for an optical sensing system. This work uses a commercial FBG with a 1550 nm center wavelength to measure the spectral response of FBG to strain. The effective refractive index (1.46), the grating period (Λ) for 530 nm in the FBG performance, the fluctuations in refractive index (∆n) from 0.0002 to 0.0020, and the fiber grating length (L) from 1 to 10 mm are the parameters used in these simulations. The bandwidth and spectrum reflectivity can be obtained by analyzing the refractive index and grating length fluctuation. OriginPro Software and Microsoft Excel are used to perform simulations on the FBG. Data are generated using the Excel sheet, and visualisations are produced using OriginPro Software. The obtained results show that the bandwidth and spectral reflectivity are impacted by variations in the refractive index and grating length. Furthermore, the obtained results indicate that variations in the Bragg wavelength can be attributed to an elongation of the grating zone caused by the applied strain.
A Secure Fusion: Elliptic Curve Encryption Integrated with LSB Steganography for Hidden Communication
Authors: El-Taj Homam
Published: September 2024

In today's digital age, ensuring secure communication is essential. This article presents a novel approach for hidden communication by integrating Elliptic Curve Encryption (ECE) with Least Significant Bit (LSB) Steganography.
Our proposed fusion offers a robust solution, Stegno Curve for concealing sensitive information within innocuous cover media while encrypting it using elliptic curve cryptography. By leveraging the strengths of both techniques, we achieve enhanced security and confidentiality in data transmission.
Through a comprehensive literature review, methodology explanation, security analysis, and implementation details, we demonstrate the feasibility and effectiveness of the Stegno Curve Method. The findings of this study not only contribute to advancing the field of secure communication but also open avenues for practical applications in various domains, such as secure cloud transitions, smart home technologies, and data encryption.
Size-dependent nonlinear analysis of three-dimensional cantilever beams with strain gradient effects using mixed finite element method
Authors: Gholami Mohammad , Alizadeh Mansour
Published: September 2024

In this study, the geometric nonlinear behavior of three-dimensional
size-dependent beams is investigated using the mixed finite element
method. Nonlinear von-Karman terms are considered in the strain–
displacement relation to capture the geometric nonlinear deformations at
higher load magnitudes. The torsion– bending deformation of
size-dependent beams is studied using the simplified form of rotation
gradient theory. The governing equations and related boundary conditions
were derived using the variational principle. The Newton-Raphson
iteration procedure for solving nonlinear governing equations is coded
in Python using a stable 11-node tetrahedral C0 element via the robust
open-source finite element FEniCS platform. The accuracy and convergency
of this formulation are examined via existing results. The effects of
Poisson’s ratio, thickness, and dimensionless length scale parameters on
the displacement and rotation fields were explored. By varying the
location of the applied load through the width of the beam, the effect
of combined bending-torsion of the cantilever size-dependent beam is
studied.
New Submission on 1st aug
Authors: Zainab safi
Published: September 2024

hi
Analysis of laser beam welding with superimposed 445 and 1070 nm wavelength lasers on copper by in situ synchrotron diagnostics
Authors: Spurk Christoph , Dietrich Frederik , Brüggenjürgen Jan , Hummel Marc , Häusler André , Olowinsky Alexander , Gillner Arnold , Beckmann Felix , Moosmann Julian
Published: September 2024

In laser welding, precision and reproducibility are fundamentally dependent on temporal and spatial processes of energy input. Induced by the dynamics of the melt pool, pressure equilibria in the vapor capillary, and solidification behavior, different weld seam qualities are achieved. To obtain the lowest possible defect frequency, new tailored joining strategies need to be investigated using multibeam and multiwavelength approaches. To improve the quality by influencing the process dynamics, a dual-beam approach is investigated that superimposes a stationary laser beam with a wavelength of 445 nm with a spatially modulated laser beam with a wavelength of 1070 nm. The aim is to utilize ∼10 times higher absorption of a 445 nm diode laser on copper with the high focusability of a 1070 nm fiber laser. In this context, the influence of the relative positions of the two beams to each other on the weld seam quality is investigated, while one of the beams moves either in front, behind, or coaxial to the other beam following the path of a line weld. The main objective is to observe how the laser beams influence each other and how the capillary depth and porosity vary for different parameters. To visualize the process dynamics, the welding experiments on copper are performed at the Deutsches Elektronen-Synchrotron DESY by means of in situ phase contrast videography. Quality-determining weld properties like the distribution of pores or process fluctuations are then extracted automatically from the image sequences by means of a trained neuronal network.
Rentabilidad privada de la educación en la zona urbana y rural del Estado de México, 2020 y 2022
Authors: Figueroa Hernández Esther , Pérez Figueroa Rebeca Alejandra
Published: September 2024

El objetivo del estudio fue estimar la rentabilidad privada de la educación para las zonas, rural y urbana del Estado de México. Para ello, se utilizó el modelo de Mincer con datos de la ENIGH 2020 y 2022 de los jefes del hogar separadas por género. Los principales resultados fueron que las tasas de rentabilidad de la educación para el sexo femenino y masculino fueron menores para la rural (4.7%, 6.5%) que para la urbana (7.6%, 8.8%). Los Modelos Spline (2020), la rentabilidad de educación primaria fue mayor para la zona urbana de las madres (7.01%) que para los padres (6.8%), la secundaria fue mayor para las jefas (9.48%) de la urbana. Para la universidad fue alto para ambas zonas, excepto para las mujeres de la urbana. Para 2022, la primaria fue menor para las madres que para los hombres de la rural y la urbana, la secundaria fue mayor para ambos géneros de la rural y negativos para la urbana. Para la universidad fue mayor para las mujeres (45.3%) que los hombres de la urbana (22.8%) y para la rural fue mayor para mujeres (44.6%). Los resultados presentados mostraron concordancia con lo que plantea la teoría del capital humano.