bluuebunny/crossref_metadata_2025 huggingface dataset:
Antigenic Characterization of Circulating and Emerging SARS-CoV-2 Variants in the U.S. throughout the Delta to Omicron Waves
Authors: Di Han , Pusch Elizabeth A. , Jones Joyce , Kovacs Nicholas A. , Hassell Norman , Sheth Mili , Lynn Kelly Sabrina , Keller Matthew W. , Wilson Malania M. , Keong Lisa M. , Cui Dan , Park So Hee , Chau Reina , Lacek Kristine A. , Liddell Jimma D. , Kirby Marie K. , Yang Genyan , Johnson Monique , Thor Sharmi , Zanders Natosha , Feng Chenchen , Surie Diya , DeCuir Jennifer , Lester Sandra N. , Atherton Lydia , Hicks Heather , Tamin Azaibi , Harcourt Jennifer L. , Coughlin Melissa M. , Self Wesley H. , Rhoads Jillian P. , Gibbs Kevin W. , Hager David N. , Shapiro Nathan I. , Exline Matthew C. , Lauring Adam S. , Rambo-Martin Benjamin , Paden Clinton R. , Kondor Rebecca J. , Lee Justin S. , Barnes John R. , Thornburg Natalie J. , Zhou Bin , Wentworth David E. , Davis Charles Todd
Published: May 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into numerous lineages with unique spike mutations and caused multiple epidemics domestically and globally. Although COVID-19 vaccines are available, new variants with the capacity for immune evasion continue to emerge. To understand and characterize the evolution of circulating SARS-CoV-2 variants in the U.S., the Centers for Disease Control and Prevention (CDC) initiated the National SARS-CoV-2 Strain Surveillance (NS3) program and has received thousands of SARS-CoV-2 clinical specimens from across the nation as part of a genotype to phenotype characterization process. Focus reduction neutralization with various antisera was used to antigenically characterize 143 SARS-CoV-2 Delta, Mu and Omicron subvariants from selected clinical specimens received between May 2021 and February 2023, representing a total of 59 unique spike protein sequences. BA.4/5 subvariants BU.1, BQ.1.1, CR.1.1, CQ.2 and BA.4/5 + D420N + K444T; BA.2.75 subvariants BM.4.1.1, BA.2.75.2, CV.1; and recombinant Omicron variants XBF, XBB.1, XBB.1.5 showed the greatest escape from neutralizing antibodies when analyzed against post third-dose original monovalent vaccinee sera. Post fourth-dose bivalent vaccinee sera provided better protection against those subvariants, but substantial reductions in neutralization titers were still observed, especially among BA.4/5 subvariants with both an N-terminal domain (NTD) deletion and receptor binding domain (RBD) substitutions K444M + N460K and recombinant Omicron variants. This analysis demonstrated a framework for long-term systematic genotype to antigenic characterization of circulating and emerging SARS-CoV-2 variants in the U.S., which is critical to assessing their potential impact on the effectiveness of current vaccines and antigen recommendations for future updates.
Assessing Climate-Change-Driven Impacts on Water Scarcity: A Case Study of Low-Flow Dynamics in the Lower Kalu River Basin, Sri Lanka
Authors: Fernando Rangika , Ratnasooriya Harsha , Bamunawala Janaka , Sirisena Jeewanthi , Nipuni Odara Merenchi Galappaththige , Gunawardhana Luminda , Rajapakse Lalith
Published: May 2024

The adverse impacts of climate change are becoming more frequent and severe worldwide, and Sri Lanka has been identified as one of the most severely affected countries. Hence, it is vital to understand the plausible climate-change-driven impacts on water resources to ensure water security and socio-economic well-being. This study presents novel assessments on low-flow dynamics along the lower Kalu River Basin, Sri Lanka, and water availability during the dry spells of the 2030–2060 period. Bias-corrected daily precipitation projections of a high resolution (25 km × 25 km) NCC-NORESM1-M regional climate model is used here to force a calibrated HEC-HMS hydrological model to project catchment discharge during the future period considered under the two end-member Representative Concentration Pathways (i.e., RCP 2.6 and RCP 8.5). Our results show that the study area (i.e., Kuda Ganga sub-basin) may become warmer (in non-monsoonal periods) and wetter (in monsoon season) under both scenarios during the near future (2030–2040) when compared to the baseline period (1976–2005) considered. Consequently, the streamflow may reduce, making it the decade with the largest water deficit within the time horizon. The subsequent deficit volume assessment for the 2031–2040 period shows a probable water shortage (~5 million m3) under the RCP 2.6 scenario, which may last for ~47 days with an average daily intensity of 105,000 m3. Our results highlight the need of incorporating climate-change-driven impacts in water resources management plans to ensure water security.
Assessing Pipe Condition in Water Distribution Networks
Authors: Cabral Marta , Gray Duarte , Brentan Bruno , Covas Dídia
Published: May 2024

The condition assessment of water distribution pipes is of utmost importance for the prioritization of rehabilitation interventions. However, the application of available methodologies for condition assessment by water utilities with limited human, technological and financial resources is becoming increasingly complex. The current paper aims at the development and application of a methodology for the prediction of the physical condition of water distribution pipes without the need for visual inspection. The methodology includes the development and application of three different algorithms (heuristic, linear regression and support vector regression). The methodology is applied to a water distribution network located in the Algarve region, Portugal. The results obtained from each algorithm are compared with a well-known performance indicator, the ratio of useful life, and present significant differences in its overall pipe condition classification. Results have demonstrated the following: the ratio of useful life tends to distribute pipe classification more equally in the three classes (i.e., good, average and unsatisfactory); the heuristic algorithm classifies most pipes as average condition; and the linear regression algorithm classifies with unsatisfactory conditions. The support vector regression algorithm stands out as the main classifier for identifying pipes in good condition when compared to other algorithms.
Estimating Stage-Frequency Curves for Engineering Design in Small Ungauged Arctic Watersheds
Authors: Engel Chandler , Wagner Anna , Giovando Jeremy , Ho David , Morriss Blaine , Deeb Elias
Published: May 2024

The design of hydraulic structures in the Arctic is complicated by shallow relief, which cause unique runoff processes that promote snow-damming and refreeze of runoff. We discuss the challenges encountered in modeling snowmelt runoff into two coastal freshwater lagoons in Utqiaġvik, Alaska. Stage-frequency curves with quantified uncertainty were required to design two new discharge gates that would allow snowmelt runoff flows through a proposed coastal revetment. To estimate runoff hydrographs arriving at the lagoons, we modeled snowpack accumulation and ablation using SnowModel which in turn was used to force a physically-based hydraulic runoff model (HEC-RAS). Our results demonstrate the successful development of stage-frequency curves by incorporating a Monte Carlo simulation approach that quantifies the variability in runoff timing and volume. Our process highlights the complexities of Arctic hydrology by incorporating significant delays in runoff onset due to localized snow accumulation and melting processes. This methodology not only addresses the uncertainty in snow-damming and refreeze processes which affect the arrival time of snowmelt inflow peaks, but is also adaptable for application in other challenging environments where secondary runoff processes are predominant.
Linking Nutrient Dynamics with Urbanization Degree and Flood Control Reservoirs on the Bahlui River
Authors: Marcoie Nicolae , Chihaia Șerban , Hrăniciuc Tomi Alexăndrel , Balan Cătălin Dumitrel , Drăgoi Elena Niculina , Nechita Mircea-Teodor
Published: May 2024

This work analyzed the nutrient dynamics (2011–2022) and discharge (2005–2022) for the Bahlui River at four distinctive locations: Parcovaci—a dam-protected area that has been untouched by agriculture or urbanization; Belcesti—a primarily agricultural area, also dam-protected; Podu Iloaiei—a region influenced by agriculture and urbanization; and Holboca—placed after a heavily urbanized area. The analysis focused on determining a series of statistical indicators using the Minitab 21.2 software. Two drought intervals and one flood interval were analyzed to highlight daily discharge evolution during the selected period, showing that the constructed reservoirs successfully control the streamflow. For the entire period, the evolution of mean and median values of the streamflow is consistent, considering the locations’ positions from the source to the river’s end. The total nitrogen and total phosphorus were selected as representative quality indicators. The study follows the influence of the analyzed areas’ characteristics and reservoirs’ presence on nutrient dynamics. The results showed that the most influential factor that impacts nutrient dynamics is the reservoirs’ presence, which controls the discharge, creates wetlands and swamps, and implicitly impacts nutrient concentration.
Ice-Jam Investigations along the Oder River Based on Satellite and UAV Data
Authors: Möldner Fabian , Hentschel Bernd , Carstensen Dirk
Published: May 2024

The Oder River, situated along the border between Poland and Germany, is regularly affected by ice-jam events and their associated hazards, such as a sudden rise in water level and the endangerment to flood-protection infrastructure. The existing databases on past ice-jam events lack substantial information considering ice formation, blockage origins or the spatiotemporal evolution of the ice cover needed for a comprehensive understanding of relevant ice processes. Within this study, the evaluation of satellite and Uncrewed Aerial Vehicle (UAV) data was carried out in order to analyze the capabilities of enhancing river ice information in the study area. Satellite imagery was proven to be a valuable source of investigating ice-jam phenomena on all scales, leading to the identification of initial ice-jam locations, surveying spatiotemporal ice cover evolution or monitoring the maximum ice-cover extent. A simplified approach for river ice classification of satellite radar data using the K-Means Cluster Analysis is introduced, enabling the differentiation between river ice formations. Based on UAV data taken in this study, workflows were presented, allowing for measurements of ice floe velocities and the localization of flooded and ice-covered flow control structures.
A Comprehensive Approach to Azo Dichlorotriazine Dye Treatment: Assessing the Impact of Physical, Chemical, and Biological Treatment Methods through Statistical Analysis of Experimental Data
Authors: Hassan Gamal K. , Ghaly Montaser Y. , Ahmed Ghada E. , Mohamed Rehab M. , El-Gawad Heba A. , Kowal Przemysław , Al-Hazmi Hussein E. , Afify Ahmed A.
Published: May 2024

This exploration investigates integrated treatment systems combining advanced oxidation processes (Fenton and photo-Fenton) with biological methods for the effective elimination of stubborn organic compounds in simulated textile wastewater composed of azo Dichlorotriazine dye. A comprehensive optimization of key process factors including catalyst dosage, hydrogen peroxide quantity, irradiation duration, etc. was systematically conducted for both Fenton and photo-Fenton processes to realize maximum COD and color removal. Under ideal conditions (0.4 g/L photocatalyst, 1 mL/L H2O2, and 75-Watt UV intensity for 60 min), the photo-Fenton process realized 80% COD elimination and complete decolorization, meeting industrial discharge limits without needing extra biological treatment. Statistical models correlating process parameters to treatment efficiency were developed, giving important design insights. For Fenton, effluent COD exceeded discharge thresholds, so a post-biological treatment using activated sludge was essential to comply with regulations. This integrated Fenton–biological scheme utilizes synergism between chemical and biological processes for enhanced overall treatment. Notable economic benefits were achieved by photo-Fenton over conventional UV-only and UV/H2O2 methods regarding energy consumption and operating costs. Overall, this pioneering work successfully proves integrated advanced oxidation–biological systems as a superior, sustainable alternative to traditional techniques for economically removing obstinate pollutants, such as azo Dichlorotriazine dye, as it is a simulated textile wastewater treatment used to satisfy environmental standards.
Actualization of practical training in medical education
Authors:   Federal State Budgetary Educational Institution of Higher Education “Russian Economic University named after G. Plekhanov”, Ministry of Science and Higher Education of the Russian Federation, Moscow, Russia, Lebedev V.A. , Lebedeva E.I. ,   Non-profit Partnership “Institute of Professional Accountants and Auditors of Russia”, Moscow, Russia
Published: May 2024

Currently, the issue of the effectiveness of medical personnel training is a key issue for the healthcare sector. The target area of medical personnel training is the combination of theoretical studies and the development of practical skills in the educational process. The article provides a comparative analysis of the norms regulating the features of practical training in educational programs of different levels, the features of practical training in medical education programs. Network forms of practical training implementation, requirements for their resource provision, as well as existing provisions regulating practical training in medical education programs and directions for its improvement are considered.
Social aspects of training organization for people with limited health capacities, special educational needs and disabilities in Russia
Authors:   FSBEI HE Ufa University of Science and Technology, Belyakova N. V.
Published: May 2024

The article examines the issues related to the provision of social services to the elderly in their home environment. The author of the article examines the practice and evaluates its effectiveness and impact on the lives of senior citizens. The article discusses the main types of in-home services, including medical care, assistance with tidiness and personal hygiene, as well as social support. The importance of the practice of in-home social services for the elderly is emphasized. It has been found that this practice allows senior citizens to maintain independence, dignity, and quality of life, as well as prevents social isolation.
Stability of the social and labor sphere of the Russian Federation in 2023 is ensured by the constructive position of social partners
Authors:   Research and Monitoring Center «Labor Conflicts» Saint Petersburg Humanitarian University of Trade Unions, Dovganenko А. А.
Published: May 2024

The article was prepared based on the materials of the analytical bulletin of the Center for Monitoring and Analysis of Social and Labor Conflicts of the Saint Petersburg Humanitarian University of Trade Unions. A number of key external and internal factors that influenced the social and labor sphere in the Russian Federation throughout 2023 have been identified. The author comes to the conclusion that the social and labor situation in the past year remained stable with low conflict potential, without the risk of deterioration in the medium term. Industry differences in the causes of social and labor conflicts show that in the most conflict-ridden industries, the sources of confrontations are contradictions in labor relations (low wages, violations of working conditions, and non-payment of bonuses).
Efectos del tiempo de congelación en las características bromatológicas de Arazá (Eugenia stipitata) aplicando modelos matemáticos
Authors: Falconí Novillo José Francisco
Published: May 2024

El arazá es una fruta que proviene principalmente de la región amazónica del Ecuador la cual posee características sensoriales y nutricionales únicas, destacando el contenido de vitamina C que supera a la naranja en un 37%. Por los que nos trazamos como objetivo evaluar los efectos del tiempo de congelación en las características bromatológicas de Arazá (Eugenia stipitata) aplicando modelos matemáticos. Los frutos cosecharon en la ciudadela Dager, ubicada en la ciudad de Milagro que pertenece a la provincia del Guayas del Ecuador, a los cuales se le determinaron contenido de humedad, proteína y cenizas, se estimaron los parámetros anteriormente mencionados aplicando modelos matemáticos en RStudio; posteriormente se sometió a una temperatura de -18°C y de determinaron la densidad, tiempo de congelación, calor especifico según modelos de Choi y Okos, temperatura final de congelación y análisis de sensibilidad. El fruto con bajo en fibra, ceniza y grasas con 0.4, 0.14 y 0.5 %, respectivamente, mientras que altos el proteína, humedad y carbohidratos (0.51, 91.45 y 7 %), efecto de la temperatura con incrementos de la densidad 2.75 kg/m3, disminuye en 2.17 kJ/kg°C el calor específico, temperatura congelación media de -7.13 °C y que esta es alcanzada a 2.98 horas. En base al análisis de sensibilidad se determinó que a medida que disminuyen los parámetros de temperatura externa, fracción de agua y densidad de la fruta, el tiempo de congelación disminuye y viceversa, ya que a  partir de una temperatura externa de 28°C por cada 6,5°C que se reduce el tiempo de congelación disminuye un 3,02%; al tener una fracción de agua de 0,9145 por cada 0,02 unidades que se reduce de este parámetro el tiempo de congelación disminuye un 1%; partiendo de una densidad de 1040,50 Kg/m3 se determinó que por cada 49,5 unidades que disminuye este parámetro el tiempo de congelación se reduce en un 5%.
Productividad del cultivo de Naranja (Citrus sinensis L.) con la aplicación foliar de bioestimulante
Authors: Sánchez Jara Raul , Irala Alonso Romina , Fleitas Quintana Celia Antonela , Fleitas Quintana Lidia Raquel , Leguizamón Resquin Adolfo
Published: May 2024

La utilización de bioestimulantes en el cultivo de naranjas Citrus sinensis L. reviste una singular importancia al mejorar el rendimiento y la calidad de la calidad de los frutos. En este sentido, el objetivo de la investigación consistió en evaluar la productividad del cultivo de naranja (Citrus sinensis) con y sin aplicación de un bioestimulante foliar. La presente investigación se realizó en la granja Don Santiago, ubicado en la localidad de Romero Potrero, en el Distrito y Departamento de Concepción, en Paraguay, en el periodo comprendido entre los meses de julio del año 2022 a mayo del 2023. Se utilizó un diseño experimental de bloques completos al azar, dispuesto en esquema factorial (2x2). Se midió el peso individual de fruto, diámetro polar de fruto, diámetro ecuatorial de fruto, grado brix y rendimiento de frutos. Los valores obtenidos fueron sometidos a análisis de varianza mediante el Test F y las medias de cada tratamiento, comparadas entre sí por el Test de Tukey al 5%. Se concluye que, la aplicación de bioestimulante en el cultivo de la variedad de Washington Navel, arrojaron mejores valores en las determinaciones de peso individual de fruto, diámetro polar, ecuatorial y rendimiento del fruto. Para el grado brix, demostró una mejor combinación, la aplicación de bioestimulante en la variedad Valencia (7,56%).
Pengaruh Dukungan Pemerintah dan Pengalaman Terhadap Kinerja Pelaku Usaha Mikro Perempuan di Medan
Authors: GUCI DEDE , Butarbutar Mangasi , Sri Astuti Doloksaribu Winda , Yunior Khomeiny , Natalia Pasaribu Lidya , Hutagaol Jarungjung , Alamsyah Harahap Rahmat , Br Bangun Nirwana
Published: May 2024

Kinerja Usaha Mikro dinilai sebagai salah satu motor penggerak berkembangnya negara-negara seperti Indonesia, yang perekonomiannya telah memperoleh manfaat besar dari kontribusi Usaha Mikro. Beberapa faktor kunci keberhasilan adalah dukungan pemerintah dan pengalaman. Tujuan dari Penelitian ini bertujuan untuk mengidentifikasi apakah ada hubungan antara dukungan pemerintah, pengalaman dan kinerja usaha Mikro yang beroperasi di kota Medan, Indonesia. Dua Ratusan responden pengusaha perempuan telah dipilih dalam studi lapangan dari tiga kecamatan di Medan, Indonesia; Kecamatan Medan Belawan, Kecamatan Medan Marelan dan Kecamatan Labuhan. Kuesioner yang disebarkan terdiri dari tiga variabel, dimana ada dua variabel bebas dan satu lagi variabel terikat. Dengan menggunakan korelasi Spearman diketahui bahwa masing-masing variabel independen mempunyai korelasi yang kuat dengan variabel tunggal. dapat disimpulkan bahwa dukungan pemerintah dan pengalaman pengusaha Perempuan skala Mikro memiliki hubungan yang signifikan.
SOSIALISASI BISNIS DIGITAL UNTUK SISWA-SISWI SEKOLAH MENENGAH KEJURUAN (SMKS PRIMA TIARA MAKASSAR)
Authors: Mashud Mashud , P Ramlah , Askar Muhammad Ichfan , Hatta Muh. Sunar , Hermawan Dellas Wahyu
Published: May 2024

Digital business atau disebut juga bisnis digital adalah bisnis tercanggih saat ini yang diperkirakan terus berkembang setiap tahun dan semakin lama akan meningkat tajam. Seiring dengan perkembangan teknologi informasi yang bergerak sangat cepat baik dibidang pendidikan, bisnis, pemasaran dan bidang lainnya. Sekolah Menengah Kejuruan (SMK) lebih fokus pada penyiapan siswanya untuk memasuki dunia kerja. SMK membekali siswanya untuk bisa bekerja secara mandiri dan terampil. Kegiatan pengabdian ini menggunakan metode sosialisasi dan metode diskusi. Proses sosialisasi terkait bisnis digital ini disajikan dalam bentuk pemaparan materi secara langsung. kegiatan pengabdian masyarakat ini diharapkan akan memberikan wawasan dan inspirasi bagi siswa-siswi SMK Prima Tiara Makassar yang tertarik untuk menjelajahi potensi bisnis digital.
O incumprimento dos empréstimos no mercado de microcrédito do sistema bancário angolano “estudo de caso aplicado na cidade Lubango-Huíla”
Authors: Somandjinga Justino Lekwa Ekuva
Published: May 2024

O presente artigo teve como objectivo analisar os factores responsáveis pelo incumprimento dos empréstimos no mercado de Microcrédito do sistema Bancário Angolano, especificamente na Cidade do Lubango. Incumprimento do crédito pode ser definido como o não pagamento dos compromissos financeiros por parte daquele que recorreu ao crédito e traduz em primeira linha a violação do contrato de empréstimo.  O estudo segue uma abordagem quantitativa, com a utilização do modelo econométrico de regressão logística. O resultados evidenciaram  que o coeficiente da taxa de juro (β = 1,36), exerce um efeito positivo no incumprimento do crédito concedido pelas instituições bancárias do Lubango. O modelo estimado mostrou-nos que as taxas de juro altas custam mais a pagar do que as taxas de juro baixas. Por sua vez, cada unidade a mais na taxa de juro aumenta a probabilidade de incumprimento do crédito concedido pelas instituições bancárias do Lubango .
Agroecologia: estratégias para agricultura sustentável
Authors: Oliveira Nayara Carina de , Araujo Roberto Bessa de
Published: May 2024

A agricultura é um dos principais responsáveis pela economia do Brasil. É uma atividade que necessita de atenção e responsabilidade. Pois a necessidade do consumo alimentício aumenta de acordo com o crescimento da população. Para que a agricultura atinja o ápice da produção desejada é necessário evitar a reestruturação da floresta natural da região e com isso as consequências são impactos ambientais. A agroecologia visa integrar a agricultura sustentável com a agricultura convencional, para tentar minimizar os prejuízos no meio ambiente. Este estudo teve como objetivo realizar uma pesquisa sobre a importância da agricultura no Brasil, analisar as estratégias utilizadas e a viabilidade socioeconômica dos sistemas agroecológicos, na perspectiva de contribuir com o equilíbrio ambiental e desenvolvimento agrícola. A agroecologia torna mais harmoniosa a relação do homem com o meio ambiente exercendo um importante papel na construção social do ser humano, porém ainda necessita de muitas mudanças e melhorias.
Biosignature Detection from Amino Acid Enantiomers with Portable Gas Chromatography Systems
Authors: Blase Ryan C. , Libardoni Mark J. , Glein Christopher R. , Miller Kelly E. , Waite J. Hunter , Li Maxwell Wei-hao , Kurabayashi Katsuo , Fan Xudong
Published: May 2024

This paper presents developments in stationary phase coatings for microelectromechanical system gas chromatography (MEMS GC). Specifically, we present the coating of MEMS GC separation columns with a chiral stationary phase for the separation of amino acid enantiomers. Three commercial columns coated with chiral stationary phases from Restek were tested: Rt-βDEXm, Rt-βDEXsm, and Rt-βDEXsa. Four amino acid enantiomers (
d
- and
l
-) were tested with the 3 commercial columns: alanine (Ala), valine (Val), leucine (Leu), and aspartic acid (Asp). The Rt-βDEXsm column provided the best experimental performance with separation of
d
- and
l
-Ala and partial separation of
d
- and
l
-Asp. The resolution,

R
s

, values were 4.65 for the Ala enantiomers and 0.98 for the Asp enantiomers, respectively. The Rt-βDEXsm chiral stationary phase was dynamically coated on three 10-m-long microcolumns connected in series to investigate amino acid enantiomer separation. Successful separation of
d
- and
l
-Ala and partial separation of
d
- and
l
-Asp were observed with the microcolumns. The

R
s

values from the chiral-stationary-phase-coated microcolumns were 1.21 and 0.553 for the Ala and Asp enantiomers, respectively. The chromatographically separated amino acid enantiomers were detected by the MAss Spectrometer for Planetary EXploration (MASPEX), a spaceflight mass spectrometer. Future work is required for improving the MEMS GC separation column performance consisting of testing static versus dynamic coating methods and more rigorous investigation of the stationary phase coating thickness. A discussion is provided on future work for the development of an MEMS GC suite targeting broad analyte selectivity for future space science missions.
Low-Molecular-Weight PEGs for Cryopreservation of Stem Cell Spheroids
Authors: Patel Madhumita , Vernon Brent , Jeong Byeongmoon
Published: May 2024

Stem cell spheroids (SCSs) are a valuable tool in stem cell research and regenerative medicine. SCSs provide a platform for stem cell behavior in a more biologically relevant context with enhanced cell–cell communications. In this study, we investigated the recovery of SCSs after cryopreservation at –196 °C for 7 days. Prior to cryopreservation, the SCSs were preincubated for 0 h (no preincubation), 2 h, 4 h, and 6 h at 37 °C in the presence of low-molecular-weight poly(ethylene glycol) (PEG) with molecular weights of 200, 400, and 600 Da. The recovery rate of SCSs was markedly affected by both the PEG molecular weight and the preincubation time. Specifically, when SCSs were preincubated with a PEG200 solution for 2 to 6 h, it significantly enhanced the recovery rate of the SCSs. Internalization of PEG200 through simple diffusion into the SCSs may be the cryoprotective mechanism. The PEG200 diffuses into the SCSs, which not only suppresses osmotic pressure development inside the cell but also inhibits ice formation. The recovered SCSs demonstrated both fusibility and capabilities for proliferation and differentiation comparable to SCSs recovered after dimethyl sulfoxide 10% cryopreservation. This study indicates that PEG200 serves as an effective cryoprotectant for SCSs. A simple preincubation procedure in the presence of the polymer greatly improves the recovery rate of SCSs from cryopreservation.
RESEARCH OF INFLUENCE OF SOLVENT NATURE ON REDUCED VISCOSITY OF POLYIMIDES OBTAINED BY HIGH-TEMPERATURE POLYCYCLIZATION IN SOLUTION
Authors:   Volgograd State Technical University, NOVAKOV I.A. , ORLINSON B.S. ,   Volgograd State Technical University, BRUNILIN R.V. ,   Volgograd State Technical University, MIKHAILINA E.V. ,   Volgograd State Technical University
Published: May 2024

The regularities of obtaining polyimides by high-temperature polycyclization in various solvents have been studied. It is shown that the use of sulfolane as a solvent makes it possible to obtain polymers with a higher reduced viscosity and, accordingly, a better potential set of characteristics. Polyimides based on vicinally substituted bicyclic diamines have a higher molecular weight compared to polyimides based on 9.9-bis-(4-aminophenyl) fluorene.
STUDY OF THE PROCESS OF OXIDATION OF MORPHOLINE AND ITS DERIVATIVES FOR OBTAINING POLYMERIZATION INHIBITORS
Authors:   Volgograd State Technical University, ORLOVA S.A. , TUZHIKOV O.I. ,   Volgograd State Technical University, KHOKHLOVA T.V. ,   Volgograd State Technical University, TUZHIKOV O.O. ,   Volgograd State Technical University, LAVNIKOVA I.V. ,   Volgograd State Technical University
Published: May 2024

The process of oxidation of morpholine and its derivatives by hydrogen peroxide in an aqueous medium has been studied. The effect of component ratios and synthesis conditions on the yield of products was studied. The compositions of the reaction products were confirmed by elemental analysis, IR, chromato-mass spectroscopy, and the physicochemical properties were studied. The possibility of their use as polymerization inhibitors was studied using styrene as an example.
LATEX-RESORCINFORMALDEHYDE IMPREGNATING COMPOUND USING A BLOCKED POLYZOCYANATE
Authors:   Volgograd State Technical University, PUCHKOV A.F. , SPIRIDONOVA M.P. ,   Volgograd State Technical University, SYCHEV A.V. ,   Volgograd State Technical University, SVINUKHOV D.S. ,   Volgograd State Technical University, DROZDEV V.A. ,   Volgograd State Technical University, KOSOBOKOVA S.D. ,   Volgograd State Technical University
Published: May 2024

The paper presents experimental data showing that the composition of the impregnation composition based on latex "Playkord" and the aqueous dispersion of the blocked polyisocyanate is able to create a durable rubber cord system without preimpregnation of the polyester cord with blocked diisocyanate.
DETERMINATION OF KINEMATIC PARAMETERS OF ACTUATORS FOR THE IMPLEMENTATION OF PROGRAM TRAJECTORIES
Authors:   Volgograd State Technical University, ZHOGA V.V. , NELYUBOVA A.V. ,   Volgograd State Technical University
Published: May 2024

The conditions of controllability of a manipulator of a parallel-sequential structure with an additional geometric connection are considered. A connection is established between the speeds of the actuators and the kinematic parameters of the program trajectories. The special positions of the manipulator mechanism are determined.
ROBOT MOVEMENT PLANNING WITH BYPASSING A STATIC OBSTACLE ON THE BASIS OF SOLUTION OF THE VARIATIONAL PROBLEM FOR THE SPECIFIED INITIAL AND END COORDINATES, SPEEDS AND OPERATING TIME
Authors:   Volgograd State Technical University, LEONARD A.V.
Published: May 2024

The article deals with the issue of developing the method for optimal planning of the movement of a ground robot with a bypass of one static obstacle for given boundary conditions and time of movement. The proposed method to traffic planning is based on the use of only the calculus of variations with the division of planning into stages.
FEATURES OF USING TWO-AXIS ROTARY TABLES AND A SIX-AXIS MANIPULATOR IN ADDITIVE MANUFACTURING
Authors:   Volgograd State Technical University, MAKAROV A.M. , DROBOTOV A.V. ,   Volgograd State Technical University, VOLKOV I.V. ,   Volgograd State Technical University, RYZHKOV S.A. ,   Volgograd State Technical University
Published: May 2024

The features of using a two-axis rotary table and a six-axis industrial robot to increase the efficiency of additive manufacturing are considered. Methods and algorithms of joint control of devices are proposed. Synchronization of the industrial robot control system with third-party devices for two-way transmission of information without time delay is implemented.
PROBLEM OF TENSION DISTRIBUTION IN A SYSTEM OF CABLE-DRIVEN PARALLEL ROBOT: GAME THEORY FORMALIZATION
Authors:   Innopolis University, MARCHUK E.A. , SHARONOV N.G. ,   Volgograd State Technical University
Published: May 2024

The article deals with a specific problem of cable-driven parallel robot, namely the problem of tension distribution in cable system. The proposed method is based on the formalization a problem of tension distribution in terms of Game Theory, the cables assumed the players, and forces in cables assumed the resources. Optimal solution has been found with a concept of Shapley value, and then compared with a solution in non-negative least squares.
The preventive direction of modern theories of health and health-saving in public health and education
Authors: Shevchenko A.S. , Shevchenko V.V. , Brown G.W.
Published: May 2024

Background. The modern understanding of health is related to the need to prevent diseases caused by infections, lifestyle, environmental and genetic factors. Ukrainian legislation guarantees health care, but the practice of implementing laws is imperfect. The teaching of valeological disciplines in educational institutions is of great importance for the prevention of diseases. But the content of these disciplines requires constant revision from the point of view of evidence-based medicine, and the creation of new preventive programs requires theoretical justification.

Aim. To determine the content and practical significance of the modern understanding of health care in public health care and education.

Materials and Methods. Methods of bibliosemantic and system analysis were used.

Results. The theory of health and health-saving is considered using cross-cultural, discursive, norm-centric, phenomenological, holistic, axiological and integral approaches, from the perspective of evidence-based and "4P" medicine. Health-saving is shown as derived from a healthy lifestyle and valeological competence formed in the population. The best environment for the formation of a healthy lifestyle is shown to be an educational environment, the tools of formation are valeological disciplines and education of medical and social non-government organizations. The need for joint efforts of the population and medical workers to achieve better results in the prevention of socially significant diseases is determined.

Conclusions. Improvement of the preventive direction of valeological education is closely related to the competence approach, in particular, with the formation of valeological competence. The public health system should use the potential of educational valeological programs to form a healthy lifestyle in new generations during their studies at higher education institutions. For the formation of high-quality valeological programs, a permanent partnership of educators and medical professionals is necessary.

Keywords: valeological competence, evidence-based medicine, 4P medicine, Health Pedagogy.
La Universidad en casa: Reconfiguraciones socioespaciales a partir de la experiencia pandémica
Authors: Molina-Jaramillo Astrid Natalia , Muñoz-Duque Luz Adriana , Ortiz Nidia Elena
Published: May 2024

Las métricas con las que las personas suelen localizarse y producir, con los otros, los lugares que habitan han cambiado durante la pandemia por Covid-19. Este artículo tiene como objetivo retomar algunas conceptualizaciones de la psicología social ambiental para reflexionar sobre el movimiento socioespacial Universidad–Casa–Universidad impuesto por las medidas de confinamiento durante la pandemia; para avanzar en este propósito las autoras proponen una revisión narrativa de la literatura. Los resultados permiten identificar que la transformación del vínculo con los lugares, durante y tras la reciente pandemia, supone una disrupción del apego a lugares significativos que soportaban la vida cotidiana y las maneras como estos han debido reconfigurarse bajo las nuevas normativizaciones de lo socioespacial durante, y tras la declaración de finalización de la pandemia. El análisis de la literatura producida sobre la lectura de lo socioespacial, en el caso de la pandemia por Covid-19, permite a las autoras abrir la discusión conceptual sobre las relaciones personas-lugares para proponer nuevas rutas de investigación y teorización en la psicología del lugar.
Liderazgo directivo y gestión educativa en el ámbito educativo
Authors: Gonzales Freddy , Mendoza Alarcón Elías
Published: May 2024

The synergy between executive leadership and educational management in the educational field is essential to ensure the excellence of the service provided. However, obstacles such as the lack of training dedicated to leadership and budgetary constraints represent significant barriers to effective educational management. Overcoming these challenges is crucial to ensure a dynamic and high-quality educational environment. The purpose of the study is to establish the correlation between executive leadership and educational management in prominent institutions within the Cusco Educational Management Unit. Its methodology is a quantitative approach with a non-experimental correlation scope; information was collected from 234 participants through non-stratified probabilistic sampling, composed of 26 executives and 208 teachers. The study employed structured questionnaires, while the data were analyzed using the Pearson correlation coefficient. The results revealed a significant correlation of 0.763 between the themes, indicating a strong and positive relationship. It concludes that as executive leadership improves, the quality of educational management tends to increase, and vice versa: this highlights that investing in the development of leadership skills in directors is not only crucial for the effective management of resources and the implementation of educational policies but can also have a multiplier effect, improving the educational environment as a whole; in turn, effective educational management can reinforce leadership capabilities.
Epitaxial growth of Ca(Ge1−xSnx)2 with group IV 2D layers on Si substrate
Authors: Yoshizaki Takashi , Terada Tsukasa , Uematsu Yuto , Ishibe Takafumi , Nakamura Yoshiaki
Published: May 2024

Two-dimensional (2D) material is drawing considerable attention as a promising thermoelectric material. This study establishes the formation method of renewed Ca-intercalated group IV 2D materials, Ca(Ge1−x
Sn
x
)2 crystals including germanene-based 2D layers. The solid phase epitaxy allows us to form epitaxial Ca(Ge1−x
Sn
x
)2 on Si. Atomic force microscopy reveals that the Ca(Ge1−x
Sn
x
)2 has island structures. X-ray diffraction proved the epitaxial growth of the Ca(Ge1−x
Sn
x
)2 island structures and the increase of the c-axis lattice constant with Sn content increase. The formation of this renewed intermetallic compound including group IV 2D layer opens an avenue for high performance thermoelectric generator/Si.
PELATIHAN PENGEMBANGAN MEDIA PEMBELAJARAN INOVATIF BERBASIS BAHAN SEDERHANA: TRANSFORMASI EVALUASI PEMBELAJARAN UNTUK GURU SDN 20 PANGKALPINANG
Authors: Iqbal Arrosyad M , Nugroho Fandi , Fhatri Zonalisa
Published: May 2024

This training aims to provide knowledge and skills to teachers at SDN20 Pangkalpinang in developing innovative learning media based on simple materials and producing effective learning evaluations in the current era of technology. The methods used in this training include needs identification, training implementation, evaluation of learning outcomes, and monitoring and evaluation. Through this training, it is hoped that teachers can improve students' critical skills in Elementary School through the Feedback-Based Learning Model Based on the Socrative Application in the P5 Program. Needs identification is carried out through needs analysis and evaluation of teachers' learning evaluation practices, as an important initial step in designing a training program that meets their needs. This needs analysis provides a better understanding of the challenges faced by teachers in using innovative learning media based on simple materials and effective learning evaluation practices. The results of this training show an increase inknowledge and skills of teachers in developing innovative learning media and conducting learning evaluations. The training evaluation indicates that teachers feel more confident inimplementing new learning strategies and using technology in learning. Further monitoring and evaluation are needed to ensure the sustainability of implementing new learning strategies and the use of technology in learning.
Cómo no evitar la conclusión muy repugnante
Authors: Rozas Mat
Published: May 2024

En ética de poblaciones, se apela a ciertas perspectivas léxicas y de nivel crítico totalistas para evitar la conclusión repugnante. Dado que la conclusión muy repugnante es una condición de adecuación más débil, podría pensarse que estas perspectivas también nos permitirán evitar esta conclusión. En este artículo argumento que no es así. Primero, muestro que estas perspectivas léxicas no evitan la conclusión muy repugnante. Después, muestro que las perspectivas de rango crítico totalistas tampoco la evitan. Finalmente, aclaro qué perspectivas nos permiten evitar esta conclusión.
Digitalization of Higher Education in Russia: Current Problems and Development Prospects
Authors:   Central Russian Institute of Management – Branch of RANEPA, Mertsalova Svetlana L. , Tsybakova Olga V. ,   Orel Law Institute of the Ministry of the Interior of the Russian Federation named after V.V. Lukyanov
Published: May 2024

The article discusses the features and current problems of introduction of digital educational technologies in educational and pedagogical process as an integral component of digitalization of all sectors of the economy of our country. The authors managed to analyze a certain range of activities carried out by the state and aimed at solving the tasks in the field of technical transformation of education system, to trace current trends in the work of higher education institutions, to identify current problems which both students and teachers face in educational process with the help of digital technologies and the latest software systems. Summing up the results of the study, the authors came to the conclusion that it is necessary to modernize the educational process further on by promoting innovative practices and techniques, updating and digitizing educational and methodological fund, developing and creating modern software products for training personnel with interdisciplinary skills and information competencies in specialties that are really in demand in the labour market.
Regression Models with Variable Structure in Digital Economy
Authors:   Central Russian Institute of Management – Branch of RANEPA, Barbashova Ekaterina V.
Published: May 2024

The article discusses the effectiveness of dummy variable use in regression models that adequately describe indicators dynamics of socio-economic processes of complex structure. Their advantage over the models built on areas of monotonous indicators change has been proved. to estimate the parameters of the model in which qualitative characteristics are given as structural variables, one does not have to go beyond the classical least squares method, which greatly simplifies the procedure of linear regression analysis. It is shown that coefficients of dummy variables models are easy to interpret, they clearly represent the dynamic process structure with relatively little time for analytical data processing. This makes it possible to use regression models with variable structure to process the results of mass sociological surveys.
Tools for Collecting and Economic Analysis of Information Concerning Manufacturing Enterprise Resource Provision for Innovative Development
Authors:   Central Russian Institute of Management – Branch of RANEPA, Parushina Natalya V. , Mosin Artem S. ,   Central Russian Institute of Management – Branch of RANEPA
Published: May 2024

Under conditions of increasing the rate of domestic production, the availability of resources and provision of enterprises with them is a factor of success and implementation of the development strategy. Resources availability is not only the current state of the enterprise functioning. It is necessary to assess the development prospects in the future, the efficiency of using the accumulated potential and directing it to innovations related to the renewal of fixed assets, production of new products types, and use of new technologies by the enterprise employees. Directions, recommendations and suggestions related to the assessment of the existing experience and development of new knowledge in the field of analysis of resource support of production are considered in the article. The purpose of the study is to develop proposals and recommendations for the development of tools for collecting and economic analysis of information about the resource provision of a manufacturing enterprise for innovative development. Te methods of analysis used are: dynamic construction, method of absolute and relative values, comparison method, coefficient method, system approach, and data structuring technique. The sources of information used were accounting data, explanatory analytical information, data analytics of information systems Interfax, Sbis, RBK company, the All-Russian Contractor Verification System For Honest Business. As a result, the practice of collecting and analyzing information about the resource provision of a manufacturing enterprise was assessed from the point of view of readiness for innovation is given on the materials of a manufacturing enterprise. It is shown how to assess the readiness of the enterprise for further development and the effectiveness of the formation and use of resources on the basis of calculation and analysis of indicators and ratios. Management conclusions are formulated to assess the resource availability of the enterprise and innovative transformations.
Analysis of Xiaomi Technology's Brand Communication in Russia: Ingate marketing case as an example
Authors:   Ural Federal University named after the first President of Russia B.N. Yeltsin, Gao Xinru , Astratova Galina V. ,   Ural Federal University named after the first President of Russia B.N. Yeltsin,   Ural Law Institute of the Ministry of the Interior of the Russian Federation
Published: May 2024

In the context of ever-increasing global competition, the role of effective marketing communication is growing. This is especially true for brands of electronic products, since the strategy of international branding of digital goods allows to successfully promote the brand in any country, region and city. Facing the constant challenges of the external environment, Xiaomi Corporation is successfully advancing in the Russian market of smartphones and intelligent equipment (IoT). However, there are a number of problems of international communication that require immediate solutions. That is why the purpose of this paper is to analyze the marketing plan of Ingate for Xiaomi Technology in Russia from the perspective of cross-cultural brand communication, taking the current economic situation in Russia, the background of the Russian electronic products sales market, and the background of the Sino-Russian trade cooperation, and to analyze the marketing case from the perspectives of communication means, communication content, cultural adaptability, cultural integration ability, and brand localization by using literature reading and empirical analysis. We also propose improvement measures from four perspectives: setting up a marketing mechanism, improving the accuracy of user profiles, weakening audience resistance, and enriching brand driving force. The project will also provide experience in the industry's marketing communications in Russia and other countries.