bluuebunny/crossref_metadata_2025 huggingface dataset:
Performance Analysis of the Behavior Based Safety Program in Reducing Occupational Accident Rates
Authors: Ayuni Mitha Qurrota , Yusuf Muhammad , Dwiyanti Endang
Published: August 2022

Introduction: PT. X is a company that concentrates on the agricultural sector by producing ammonia and urea fertilizers. Occupational accidents at PT.X are reported and recorded by the Department of Occupational Health and Safety, one of which is a form of monitoring the performance of the BBS program at PT. X. The research objective was to determine the performance of the Behavior-Based Safety (BBS) program in reducing occupational accidents due to unsafe actions at PT.X. Methods: This study is an observational study. Determination and sampling in this study used accidental sampling technique for safety officers as many as 5 respondents, while the cluster sampling technique was used for the workforce of 95 respondents. The data analysis method used was descriptive semi-quantitative. Results: The results showed the fulfillment of the criteria and maturity level of behavior-based safety at PT. X, In general, PT X was already at level 4, namely "High Performing" with an average of 3.5. Meanwhile, the work accident rate analysis using the Safe T-score of PT. X was in the category between +2.0 and -2.0, meaning that the number of occupational accidents at PT. X after implementing behavior-based safety did not experience any significant changes. Conclusion: The performance of the behavior-based safety (BBS) program in reducing occupational accidents due to unsafe actions at PT. X in 2019 was effective even though the maturity level of the application of BBS was still not at the high performance level criteria on all criteria, and there was still no significant change in the reduction of the number of occupational accidents.
Analyzing Relationship between Safety Climate and Safety Leadership in a Phosphoric Acid Industry
Authors: Wulandari Nia Tri , Syaiful Dayinta Annisa , Dwiyanti Endang , Warda Sovia Rahmania
Published: August 2022

Introduction: Safety-based leadership style has a positive relationship with the workplace safety climate in a company. Transactional leadership has a direct positive relationship with work safety participation and has an indirect relationship with work safety climate. In a phosphoric acid industry especially in 2019, the achievement of sulfuric acid production decreased from 2019 to 2020. The gap range was caused by leadership factors. This study has an objective to analyze the overview of safety climate based on safety leadership in the phosphoric acid industry. Methods: This research used a cross-sectional quantitative survey. The respondents comprised of 44 personnel. The independent factors in this investigation were the dimensions of leadership style and the dependent variable in this study wasthe condition of the work safety climate in each work group in the creation unit. The analysis used NOSACQ-50 radar plot analysis. Results: Of all perceptions of consideration leadership style, eitherin the high, very high, or enough categories, the dimension of work safety justice had the lowest score. The highest dimension of work safety climate was in the dimension of management safety priority and ability, especially in the perception of a high and very high initiating structure leadership style. Conclusion: A very high perception of the consideration leadership style had a work safety climate that had a higher score when compared to the high and sufficient perception. The highest dimension of work safety climate was in the dimensions of management safety priority and ability, especially in the perception of a high and very high initiating structure leadership style.
The Use of Coconut Fiber Padded Seat in Reducing Vibration and Fatigue of Bus Drivers
Authors: Sunarsieh Sunarsieh , Paulina Paulina
Published: August 2022

Introduction: Environmental factors such as vibration can affect work fatigue. The previous research results showed that there was a relation between vibration and fatigue, with the use of ergonomic seats by bus drivers. Then conducting experimental research on making ergonomic seat padding made from coconut fiber to reduce the level of vibration and driver fatigue was investigated. The purpose of this research was to analyze the differences in seating vibrations and the bus driver fatigue who did not use a padding seat and one who used it. Methods: The research design was experimental. The research subjects were 42 bus drivers. The vibration intensity was measured using a vibrometer and work fatigue was measured using a reaction timer, then the data were analyzed by T-test. Results: Based on research results the vibration of bus drivers who did not use seat padding was greater than those who did (p=0.001). Those who used seat padding had lower mean fatigue than drivers who did not use it (p=0.001). Conclusion: Vibration and work fatigue in bus drivers who did not use a padding seat was greater than those who used it and the difference was statistically significant. The use of ergonomic seating for bus drivers was very useful for reducing vibration.
Correlation between Workers’ Characteristics and Workplace Noise with Subjective Hearing Disorders in Textile Industry
Authors: Damayanti Ratih , Lutfiya Indah , Mirza Esfahani Refi
Published: August 2022

Introduction: The textile manufacturing industry has a noisy work environment as a result of the weaving machines which have a noise intensity exceeding the threshold value. Noise can cause complaints of hearing disorders. Other factors that influence hearing disorders are agework period, and the use of ear protection equipment. This study aims to analyze the relationship between age, work period, the use of ear protection equipment, and noise intensity on complaints of subjective hearing disorders in the AJL Weaving Department of Textile Industry. Method: This research was a descriptive observational study with a cross sectional approach. Data were obtained by measuring noise intensity and distributing questionnaires to workers. Respondents in this study amounted to 45 people who were the total population of weaving operators and maintenance workers in the AJL Weaving Department of Textile Industry. Results: The results of this study indicate that age and work period have a sufficient relationship with complaints of subjective hearing disorders, while the use of ear protection equipment has a weak relationship with complaints of subjective hearing disorders, and noise intensity has a strong relationship with complaints of subjective hearing disorders. Conclusion: Individual characteristics only have a weak to moderate relationship with subjective hearing complaints. Meanwhile, exposure to noise intensity has a strong relationship with subjective hearing complaints.
Hydrogen Sulfide Measurement of Degraded Corrosion Inhibitor with Glass Tube Detector in Oil & Gas Industry
Authors: Sastra Ni Made Truly Pinanti , Susilowati Indri H.
Published: August 2022

Introduction: Corrosion inhibitor (CI) is injected as carbon steel pipe corrosion protection with sulfur-containing substances in the product. One type of them is thioglycolic acid (TGA). Besides having benefits in maintaining pipe integrity, TGA can be decomposed to HS (hydrogen sulfide) due to changes in ambient temperature during storage, such as direct sunlight exposure on the field. This irritant gas can pose a risk to the health of chemical workers. Therefore, this study aims to measure the concentration of H2S in a CI product containing TGA.
Method: The data were collected from an oil and gas company measurement report on 12 CI drums with 1-3%w of TGA content by using a glass tube detector. Measurements were performed by varying the measurement distance (0 and 10 cm from the mouth of the drum), observing the condition of the inflated drum surface, and determining the existence of internal pressure. Results: All samples were contained H2S, and the inflated drums had higher H2S content than those that were not inflated up to more than 200 ppm in the drum bore. At this concentration, workers can experience pulmonary edema significantly prolonged exposure. Biological monitoring can be done by analyzing thiosulfate content in urine and blood after exposure or routine examination at the end of the work shift. Conclusion: CI with TGA content has the potential of high H2S concentration, and it requires risk control such as engineering control, administration control, and PPE application to minimize the health impact of H2S exposure to the workers.
Mapping Analysis of Personal Protective Equipment Usage as an Effort to Reach Zero Accident at Ponorogo Hospital
Authors: Diannita Rindang
Published: August 2022

Introduction: One of the efforts to reduce the risk of occupational accident and occupational diseases is awareness regarding the importance of the safety and health of workers in hospitals, which is also a top priority in hospitals during a pandemic situation. The application of health protocols and the use of Personal Protective Equipment (PPE) are the main lines of defense against the risk of disease and occupational accident. So that the use of Personal Protective Equipment (PPE) is very important, especially for workers during a pandemic. The purpose of this study was to analyze the mapping of the use of Personal Protective Equipment (PPE) with the incidence of occupational accident. Methods: The research used was an analytic observational type using a cross sectional approach, besides that the researchers conducted a survey of the conditions in the hospital. With a sample of 179 respondents in all parts of the hospital. Results: There is an effect of the use of PPE on the incidence of work accidents and it is necessary to have a mapping of PPE, such as gloves, safety shoes, surgical glasses, surgical gown, apron, mask, face shield, head protection, safety helmet, safety shoes, body harness, fire-resistant clothing, fire-resistant helmet, fire-resistant goggles, and fire-resistant gloves. Conclusion: Control is needed in the form of procurement of Personal Protective Equipment at Hospital X, including face shields, aprons, gloves, masks, head protectors, and safety shoes.
Otoritarianisme-birokratik orde baru, krisis ekonomi dan politik, dan demokrasi formal masa reformasi
Authors: Rajab Budi
Published: August 2022

Since Indonesia’s new order led by Suharto rose to power, many countries have expressed admiration for the New Order (1966 – 1997), including developed countries, as an efficient and effective government, which was able to drastically reduce inflation and maintain economic growth. Previously, during the Old Order (1956-1965), the Indonesian economy stagnated, with very high inflation, even leading to bankruptcy, as well as conflicts between communists and military institutions. With the military institution winning the conflict, the New Order reversed the way of managing the state which in the Old Order era emphasized excessive political interference, so that economic development was neglected. The New Order state tried to build an economy with a capitalist system whose financing relied heavily on foreign debt and investment. foreign. Economic development is bearing fruit, poverty is reduced, education and health of the Indonesian people are better, but the political sector was controlled by the New Order State in a bureaucratic-authoritarian manner, the masses were demobilized strictly and repressively, even coercively. However, three decades later, the New Order regime was faced with an economic crisis in the mid-1990s and civil society movements and other civil groups demanding democratization of the political system. The community movement succeeded in overthrowing the New Order regime and replaced it with a reform regime. Economic development remains a priority of this reform regime in a capitalistic manner, but the democratic political system it develops is still conventional, procedural democracy, not participatory democracy, which means that although it no longer governs repressively, conventional state institutions remain strong, such as the executive, legislative, and the judiciary, while civil society groups are somewhat neglected.
Peran Botoh dalam Pemilihan Kepala Desa: Studi Konflik Politik Kepala Desa Sotabar, Kecamatan Pasean, Kabupaten Pamekasan
Authors: Akbar M. Fahri Ilham , Aribowo Aribowo
Published: August 2022

Botoh (voice brokers) in the areas of Central Java and East Java have an important role in winning the candidates carried out in the lowest level general elections (pilkades). Solid strategies in the selection of candidates are not responsible for the method of funding, surveying, and control of dominance held in the image of society. General Election of Village Heads in Sotabar Village, Pasean Subdistrict, Pamengkasan Regency is an arena for strong power shows in winning the candidates they carry. Many conflicts occur in the pilkades because of differences of opinion, struggles for power and interests. Between the election of village heads (pilkades) and the political dynamics between botoh, petahanats and the community. The findings of the data show that Botoh has an important role associated with the search for candidates to win. In addition, botoh is a person who has the legitimacy of power in society, the experience of freedom in the world of photography and high relations with political officials. When political practices were implemented, Botoh implemented mobilization by reading the conditions of the community and carried out carefully in the three groups approved by the clerics, santri and abangan through the team provided. Even in the winning process, it is through some political dynamics with other actors that cause conflict. This conflict is triggered by the relationship between slaughterhouse and petahanat related to unbalanced authority and leadership that is not in line with the expectations of the community.
Problematika netralitas Polri di era Jokowi: Keterlibatan dalam politik praktis dan bisnis
Authors: Darry Mohammad , Asri Diah
Published: August 2022

This article describes the problems of democratization that occurred in the reform era, namely the involvement of the National Police in practical politics and business. After the issuance of Presidential Instruction No. 2 of 1999 by B.J Habibie who stated that the National Police were separated from the Armed Forces, the National Police Chief was directly responsible to the President of the Republic of Indonesia through the National Police Law no. 2 of 2002. The law was issued as an effort to democratize post-reform, aimed at creating a professional security tool by prioritizing neutrality that does not involve oneself in practical politics and business. However, there are differences in the implementation of the Police Law. Along with the increase in its budget, the Police are actually involved in sectors that are not under their authority. During the Jokowi administration, this involvement was demonstrated by the distribution of 18 high-ranking officers in the ministry, 7 in non-ministerial institutions, 4 in BUMN, 2 in ambassadorial positions, and 2 in independent associations. This article was compiled through a literature study using secondary data to understand the causes of Polri's involvement in practical political and business activities. The argument of this article shows that the problem of democratization regarding the involvement of the National Police in practical politics and business by holding concurrent positions outside the corridor of security and order is caused by the interests of the authorities, which is a form of reward for President Jokowi's victory in the 2019 presidential election.
THE URGENCY TO IDENTIFY LOW MUSCLE MASS AMONG ELDERLY: COMMUNITY SERVICE IN NURSING HOME
Authors: Farapti Farapti , Fadilla Chusnul , Heriyana Amelliya Nur , Sari Afifah Nurma , Adiningsih Sri
Published: August 2022

Introduction: Decreased muscle mass in the elderly often occurs due to the aging process. Identification of muscle mass needs to be done to optimize the health status of the elderly. So, this article will identify muscle mass in the elderly.
Methods: Community service was carried out to 54 elderly people in a nursing home. For the elderly, health checks are carried out including body composition measurements, especially muscle mass, as well as nutrition education and counseling. The inclusion criteria for the elderly who take part in the activity include (1) healthy and able to stand; (2) fully aware; (3) not bed rest; (4) able to communicate and cooperative. The data presented include age, length of stay, body mass index, and body composition, namely muscle mass.
Results: About three-quarters of the elderly are women and have lived in a nursing home for approximately 3 years. The average nutritional status of the elderly is normal (21.6 ± 4.5 kg/m2). As many as 96.3% of the elderly have a low muscle mass index and 53.7% of the elderly have a high fat mass. The muscle mass of older men was higher than that of women (26.2 ± 2.8 vs 21.9 ± 1.9).
Conclusion: Almost all the elderly has low muscle mass due to the physiological aging process and decreased activity of the elderly in using muscles. . Elderly women were observed to have lower muscle mass index than that of men. Identification of muscle mass strength is also needed to find out more about sarcopenia in the elderly.
ORGANIZING COVID-19 SURVIVORS AS CONVALESCENT PLASMA DONORS
Authors: Triyono Erwin Astha , Rimbun Rimbun
Published: August 2022

Introduction: Convalescent plasma transfusion therapy remains as one of the therapies recommended by the Ministry of Health for Covid-19 patients in Indonesia. However, in its practice, this therapy is greatly constrained by the availability of plasma donors at the Indonesian Red Cross (PMI) and the few survivors who are willing to donate their blood plasma. The aims of the community service activity were to educate, organize, and facilitate the survivors to do screening and donate their plasma.
Methods: The activities were conducted in June until December 2021, at Indrapura Field Hospital (RSLI) Surabaya. A total 925 participants (641 male and 309 female) were all Covid-19 patients from RSLI Surabaya. The demographic data were collected and organized as a database. The survivor's online communication group (16 WhatsApp groups) were created, to provide information and education about Covid-19 and the importance of plasma donation to the patients and survivors.
Results: The three largest groups by age were 26-35 (30.84%), 46-55 (21.26%), and 36-45 (19.47%) years old. The 3 largest groups by city of origin were Surabaya (62.42%), Sidoarjo (16.53%), and Gresik (8.63%). About 77.89% of participants have their understanding in the convalescent plasma for Covid-19. About 43.79% of them were willing to become donors after 14-day-recovery, and have been registered in the web application of donors. The 102 survivors were also involved in free plasma screening with PMI Surabaya. Total 88 survivors who have passed the screening have given their plasma as convalescent donors.
Conclusion: Organizing and educating Covid-19 survivors were exceptionally required to encourage them to become a plasma donor. The collected survivor data must be stored and managed properly to facilitate everything related to the blood plasma. The survivors are suggested to be screened 14 days after being declared healthy, to maintain the availability of blood plasma at PMI for Covid-19 patients who necessitate the convalescent plasma therapy.
Approaches to the classification of wine aroma ageing potential. Applications to the case of terpenoids in Valpolicella red wines
Authors: Luzzini Giovanni , Slaghenaufi Davide , Ugliano Maurizio
Published: August 2022

Valpolicella is an Italian wine-producing region famous for premium red wines. Valpolicella wines often undergo a minimum ageing period between 1 and 4 years, according to the wine type. Therefore, identifying relevant types of aroma precursors and the related chemical mechanisms behind aroma development during ageing is of great importance for Valpolicella wines. This study assessed free and glycosidically-bound terpene compounds of Valpolicella wines as potential precursors of different ageing-related terpenes using a model ageing experimental approach. Results showed that terpene profiles changed substantially with ageing. The occurrence of cyclic terpenes (p-menthane-1,8-diol, 1,8-cineole and 1,4-cineole) was mostly associated with the content of free monoterpenols, linalool in particular, in young wines, whereas glycosylated monoterpenols appeared to play a minor role. Accumulation of cineoles was strongly modulated with pH; in fact, low pH values promoted higher cineole yields.
Using clustering algorithms and GPM data to identify spatial precipitation patterns over southeastern Brazil
Authors:   São Paulo State University (UNESP), Institute of Science and Technology, São José dos Campos, 12245-000, São Paulo, Brazil., Guerreiro Miranda Bruno , Galante Negri Rogério ,   São Paulo State University (UNESP), Institute of Science and Technology, São José dos Campos, 12245-000, São Paulo, Brazil., Albertani Pampuch Luana ,   São Paulo State University (UNESP), Institute of Science and Technology, São José dos Campos, 12245-000, São Paulo, Brazil.
Published: August 2022

Southeastern Brazil comprises an important geoeconomic and populous region in South America. Consequently, it is essential to analyze and understand the precipitation profiles in this region. Among different data sources and techniques available to perform such study, the use of clustering algorithms and information from the Global Precipitation Measurement (GPM) project rises as a convenient yet few exploited alternative. Precisely, this study employs the K-Means, the Hierarchical Ward, and the Self-Organizing Maps methods to cluster the annual and seasonal precipitation data from GPM project recorded from 2001 to 2019. The adopted methods are compared in terms of quantitative measures and the number of clusters defined through a well-established rule. The results demonstrate that the annual and seasonal periods are organized according to different number of clusters. Moreover, the results allow: identify the presence of a spatially heterogeneous distribution in the study area; to conclude that the K-Means algorithm is a suitable clustering method in the context of this investigation when compared to Ward’s Hierarchical and Self-Organizing Maps methods in terms of the Calinski-Harabasz and Davies-Bouldin measures; and that the spatial precipitation distribution over Southeastern Brazil is represented by 10 clusters in annual and summer periods, 11 clusters in autumn and spring and 9 clusters in winter period.
Motivasi Petani dalam Pemanfaatan Lahan Pesisir untuk Perkebunan Kelapa di Kecamatan Karimunjawa, Kabupaten Jepara
Authors: Utomo Muhammad Pambudi , Setyowati Retno , Suminah Suminah
Published: August 2022

This study aims to examine the factors forming the motivation of farmers in the use of coastal land for coconut plantations, to examine the level of motivation of farmers in the use of coastal land for coconut plantations, to examine the relationship between motivational forming factors and the level of motivation of farmers in the use of coastal land for coconut plantations. The research location is in Karimunjawa Sub-district with the consideration that sub-district is one of the sub-districts in the Jepara Regency which has the largest coconut plantation area and the largest yields. The sampling technique used is the Census Data analysis using Spearman rank. The results showed that the motivation-forming factors were age 37 to 43 years, elementary formal education, nonformal education (X1) in the rare category, a land area (X2) less than 0.5 ha, the majority of farmers' income (X3) is less than 2.000.000 IDR, cosmopolitan (X4) 1 to 2 times, the role of extension workers (X5) in the category of quite a role, family support (X6) in the supporting category, the role of community leaders (X7) in the role category and price assurance (X8) in the easy category. The level of motivation of farmers in the use of coastal land for coconut plantations (Y) includes existence motivation (Y1) in the want category, relatedness motivation (Y2) in the unwilling category and growth motivation (Y3) in the less wanted category. There is no significant relationship between X1, X2, X4, X5, X6, X7 and X8 on the Y variable, while only X3 has a significant relationship to the Y variable.
Kajian Dimensi Community-based Tourism dalam Pengembangan Desa Wisata Sumberbulu
Authors: Arum Dhiany Sukma , Padmaningrum Dwiningtyas , Winarno Joko
Published: August 2022

Tourism development is currently directed towards sustainable tourism development. Domestic tourist visits to tourist villages are still low due to the lack of promotion of tourist villages due to budget constraints and local people themselves who do not understand the existence of tourist villages. One of the tourism concepts that can be applied to utilize local communities in the area is to introduce the concept of community-based tourism (CBT). This study aims to analyze the economic, social, cultural, environmental and political aspects which are the dimensions of CBT in the development of Sumberbulu Tourism Village. The basic research method used qualitative methods through a descriptive analysis approach. The determination of the research location was carried out intentionally in the Sumberbulu Tourism Village, Karanganyar Regency. The informants used in this study were purposive and snowball. Validation of data with source triangulation techniques and triangulation techniques. Data analysis used interactive data analysis. The results of the study show that the dimensions of CBT applied by the Sumberbulu Tourism Village include economic, social, cultural, environmental and political dimensions. The economic dimension applied is in the form of development funds, job creation, income generation and joint ventures. The social dimensions applied are in the form of involving members in every aspect, developing community pride, developing a quality of life and a fair distribution of roles, strengthening organizations, and authorizing communities. The cultural dimension applied is in the form of respecting and maintaining cultural uniqueness, helping to develop learning about cultural exchange, respecting cultural differences and human dignity. The environmental dimension applied is in the form of a carrying capacity area, ensuring environmental sustainability. The political dimension applied is in the form of institutional consolidation, increasing participation, guaranteeing rights in natural resource management.
Character Education Based on Minangkabau Local Wisdom
Authors: Alhamuddin Alhamuddin , Dermawan Oki , Azis Helmi , Erlangga Revan Dwi
Published: August 2022

Character education is the most important thing in the personality of each individual. It is not only influenced by parents and education level, but character education can be influenced by the community environment, including local wisdom in an area. The purpose of this study was to determine the transformation of Islamic education in Minangkabau in relation to Islam and local culture. The research method used was a qualitative approach with ethnographic method, ethnography was used to see how the relationship between Islam and local culture in transforming the concept of Modern Islamic education in Minangkabau. The results showed that Minangkabau local traditional expressions provide guidance and advice so that they always have religious character, honesty, tolerance, responsibility and discipline, fairness, social care, courtesy, friendly and communicative, and high work ethic. Thus it can be stated that all the values ​​of character education that arise from the messages of advice in Minangkabau traditional expressions are in accordance with the Shari'ah and are exemplified by the Prophet Muhammad Saw
The Contribution of Majelis Taklim Tastafi in Shaping the Spiritual Dimension of Langsa City Community
Authors: Wildan Teuku
Published: August 2022

This study aims to determine the contribution of the majelis taklim Tastafi in shaping the spiritual dimension of the Langsa City community. Participants in the study were 30 members of the majelis taklim Tastafi. The mixed-method approach is used to answer the problem; the quantitative type uses Pearson product-moment, and the qualitative type uses the descriptive-analytical method. The results of the research findings show there is a significant relationship between the activities of the majelis taklim Tastafi in shaping the spiritual dimension of the Langsa City community, indicated by the validity test of the Pearson product-moment correlation data on the activities of the majelis taklim Tastafi and the spiritual dimension, prayer fulfilment

 

 

fields 0.959, universality 0.954 and connectedness 0.937. The null hypothesis (H0) is rejected, and the alternative hypothesis (Ha) proposed is accepted; namely, there is a positive relationship and a very significant correlation between attending majlis taklim and the spiritual dimension variables. The higher the routine in attending the majelis taklim, the higher the spiritual dimension and vice versa; this is evidenced by the validity of the data with the results of all values ​​​​of the spiritual dimension on Sig ( 2-tailed) was 0.000 (p < 0.01). The formation of the spiritual dimension is seen in the practice of worship, belief, relationship with God and humans, and individual responsibilities in life.   

Keywords: majelis, contribution, spiritual
Application of Hypnotherapy Techniques to Overcome Ailurophobia
Authors: Hidayat Dea , Gutji Nelyahardi , Wahyuni Hera , Yusra Affan
Published: August 2022

Penelitian ini didasarkan pada survei yang dilakukan di lingkungan peneliti yang menemukan adanya fobia atau ketakutan berlebihan terhadap suatu objek, dalam hal ini, peneliti menemukan kasus satu jenis fobia, yaitu Ailurofobia di mana penderita takut pada hewan kucing yang berlebihan. Penelitian ini bertujuan untuk menganalisis penerapan teknik hipnoterapi untuk mengatasi ailurofobia. Jenis penelitian ini adalah Action Research (PTL). Penelitian dilakukan pada (3) tiga tindakan, tindakan pertama dilakukan dalam 1 (satu) minggu dengan frekuensi 1 (satu) pertemuan, tindakan kedua dilakukan berdasarkan refleksi pada tindakan pertama, tindakan kedua dilakukan atas dasar refleksi pada tindakan pertama, dan tindakan ketiga dilakukan atas dasar refleksi pada tindakan kedua. Selanjutnya, hasil penelitian dilaporkan
Распространение вариантов вируса SARS-COV-2, вызывающих озабоченность (VOC) на основе количества их геномов, депонированных в базу данных GISAID за неделю с 30.07.2022 г. по 05.08.2022 г.
Authors: Дмитриева Людмила , Краснов Ярослав , Чумачкова Елена , Осина Наталья , Зимирова Анастасия , Иванова Александра , Карнаухов Игорь , Караваева Татьяна , Щербакова Светлана , Кутырев Владимир
Published: August 2022

В обзоре представлена информация по актуальным геновариантам вируса SARS-COV-2, циркулирующим в настоящее время, геномные последовательности которых размещены в международной базе данных GISAID за неделю с 30.07.2022 г. по 05.08.2022 г.
The Trillat Procedure for Anterior Glenohumeral Instability
Authors: Velasquez Garcia Ausberto , Chaney Grace K. , Ingala Martini Liborio , Valenti Philippe
Published: August 2022

» Anterior glenohumeral instability (AGI) is a challenging condition that requires close attention to osseous and soft-tissue abnormalities. The morphometric variance of the periarticular scapular anatomy may be involved in the pathogenesis of recurrent traumatic anterior instability.

» The Trillat procedure repositions the coracoid medially and downward by a partial wedge osteotomy, mimicking the sling effect of the Latarjet procedure by moving the conjoint tendon closer to the joint line in throwing position. The Trillat procedure decreases the coracohumeral distance without affecting the integrity of the subscapularis muscle and tendon.

» Joint preservation methods, such as the Trillat procedure, may be explored in older patients to treat AGI with simultaneous irreparable rotator cuff tears (RCTs) with a static centered head and a functional subscapularis.

» Shoulder hyperlaxity and instability can be challenging to treat with isolated soft-tissue procedures. In cases without glenoid bone loss, free bone block techniques are ineffective because of the subsequent potential graft resorption, apprehension, or recurrence. The Trillat surgery, in conjunction with an anteroinferior capsuloplasty, seems to be helpful in preventing recurrent instability and in reducing shoulder apprehension.

» Recently, several variations of the original technique have been described. In the future, anatomical, biomechanical, and clinical studies need to be conducted to further evaluate the morphometric characterization of the procedure, enhance the technical features, improve indications, and avoid coracoid impingement and other potential complications with the Trillat procedure.
A Novel Approach to Predict Sand Production Rate through Gravel Packs in Unconsolidated Sediment Applying the Theory of Free Fall Arch
Authors: Qi Minhui , Li Yanlong , Moghanloo Rouzbeh Ghanbar , Liu Chenwei , Wang Jintang , Liu Changling , Wu Nengyou , Sun Jinsheng
Published: August 2022

Sand production can yield severe operational issues during natural gas hydrate (NGH) exploitation. As a prerequisite for effective sand control design, a reliable simulation approach is required to predict sand production rate of the unconsolidated sediment after hydrate decomposition. In the present study, a quantitative model to predict fluid-driven sand discharge rate has been proposed by assuming an imaginary free fall arch (FFA) region at the gravel pack interface. Through integrating the FFA particle discharge model, critical remigration velocity model, and sand erosion model, a novel simulation approach is developed to determine the time-dependent permeability change of the sanding sediment during depressurization-induced hydrate exploitation. The numerical model was verified through comparison against the flooding experiments with both single opening and gravel pack. A sensitivity analysis was carried out to study parameters (such as packed gravel size, sand particle size, opening blockage, and hydrate reformation) that may affect the sanding rate and permeability distribution within the unconsolidated sediment as well. By utilizing the simulation approach proposed in this paper, the sand intrusion within the gravel pack and the permeability variation of the unconsolidated sediment can be obtained in a computationally efficient way, which is of significance in sand control design and potential geological risk identification during hydrate exploitation.
Deriving profits allocation scheme in view of the players’ risk attitudes with interval-valued cooperative games
Authors: Li Jian , Niu Li-li , Chen Qiongxia , Qiu Zhicong
Published: August 2022

Interval-valued cooperative games use interval numbers to represent the returns of coalition. It indicatives that the uncertain of the returns are emerge from the coalition. This leads to the uncertainty of the players’ returns who participating in the cooperation. The players with different risk preferences will have different attitudes towards the uncertainty of coalition returns. To address this issue, several allocation models are constructed by taking into account players’ risk attitudes. There are four types of players’ risk preference are concerned, namely, risk neutral, risk pursuit, risk aversion and risk mixed. First, to remove fuzziness of interval relationships presented in interval-valued core, the comparison method of interval numbers is utilized. Second, the allocation models are developed by taking into account decision makers’ risk attitudes and the absolute difference of two interval numbers, there are two types are concerned, that is, the allocation models respectively considering the coalition with the same satisfaction level of absolute difference and different satisfaction level of absolute difference. Third, an illustrative example is employed to demonstrate the validity and applicability of the proposed models. Finally, comparison of distribution schemes obtained in this study and obtained from other several methods are conducted.
A Recognition Method for Ballasted Railway Subgrade Defects
Authors: Hou Zhezhe , Zhao Weigang , Yang Yong
Published: August 2022

A recognition method based on sparse representation was proposed to solve the problems in subgrade detection with ground penetrating radar (GPR), such as massive data, time-frequency and difference in experience. Based on the propagation characteristics of electromagnetic waves and radar images in subgrade defects, the phase axis of radar images of railway subgrade defects was different from that of normal subgrades. The sparse representation of railway subgrade defects was studied from the aspects of the time domain, and time-frequency domain with compressive sensing theory. The high-frequency horizontal details of the radar images were obtained to reduce redundant data fetching. The demixing points, energy, and variance per block were obtained as time domain eigenvalues, and the high-frequency horizontal details of the radar images and the energy spectrum of the wavelet multiscale spatial were acquired; thus, the feature vectors of the radar signal were extracted by sparse representation. Based on FCM-GANN (fuzzy C-means and generalized regression neural network), rapid recognition of the ballasted railway was realized. Experimental results indicated that the redundancy of data was reduced, and the accuracy of identification was greatly increased.
Assessing the Fidelity of the Malaria Vaccine Implementation in Malawi
Authors: Patel Parth K. , Nyondo-Mipando Linda Alinane , Kalanga Noel
Published: August 2022

Globally, remarkable progress has been made in the fight against malaria over the last two decades, yet the rate of reduction of malaria case incidence and mortality seems stalled. Globally, malaria case incidence (i.e., cases per 1000 population at risk) reduced from 80 in 2000 to 58 in 2015 and only to 57 in 2019. Mosquirix (RTS, S/AS01), a four-dose malaria vaccine with an effectiveness of 39%, was piloted by the WHO in three countries including Malawi where it was integrated into the EPI as a regular schedule dose. Fidelity was assessed to evaluate the degree of adherence to the planned protocol for the roll out of the program. This is a qualitative study that used the implementation fidelity framework (2007) where 12 healthcare workers were interviewed, 47 parents attended 2 focused group discussions, and a non-participatory observation checklist determined the status of vaccine storage and administration, in 2 separate health centers serving as immunization clinics. Framework approach analysis was used in this study. 59 participants were interviewed in this study. 12 health workers that were interviewed, 2 (17%) were female and 10 (83%) were male whereas all 47 (100%) parents were female. The average age of HCWs was 38 years while for the parents it was 29 years. The study demonstrated fidelity to the malaria vaccine protocol but to a much lesser extent. It has to some extent been implemented with fidelity and there is demonstrable adherence to the vaccine protocol, nevertheless, numerous gaps still exist.
Immunoinformatics and MD-simulation data suggest that Omicron spike epitopes are more interacting to IgG via better MHC class-II recognition than Delta variant.
Authors: Sarkar Aniket , Santra Dipannita , Panja Anindya Sundar , maiti smarajit
Published: August 2022

Background
Recently, in Nov 2021, in South Africa, the SARS CoV-2 variant Omicron was found to be highly infectious and transmissible but with the least fatality. It occupies the nasopharynx-oropharynx and easily spreads. The epidemiological data/reports suggest that several vaccines failed to neutralize Omicron. It has a large number of spike mutations and the RNA/protein vaccines were developed from its predecessors that may justify its escape in most neutralization reactions. It’s lower immuno-suppression/cytokine-storming/inflammatory-response effects need explorations.
Objectives
In the current study, we attempted to delineate the comparative interaction of different variants’ spikes with IgG and a few HLA-typing of MHC-II.
Methods
All SARS-CoV-2 spike-proteins/human-IgG/MHC-II were obtained from the NCBI/ PDB/GISAID database. Initial 3D-structures of the unavailable proteins were constructed by Homology-Modeling (Swissmodel-Expasy) and optimized (PROCHECK). Molecular-docking of spike-IgG/spike-MHC-II was performed (HADDOCK2.4/HawkDock) with active-residue screening (CPORT). Antigenicity of epitopes was determined (Vaxigen v2.0-server) and epitope-model prepared (PEP-FOLD3-server). The binding-affinity/biological-interfaces/visualize were performed (PRODIGY-PyMOL2). We also examined Molecular-Dynamic-Simulation (myPresto verson-5) of MHC-II with different epitopes and antibody IgG with different variants. The MD-simulation was run with 9000-cycles after 300k-heating/1-atm pressure adjustment for the system-equilibration. Finally, 1000ps production was run.
Results
Surface-area with interactomes, H-bonding and polar/non-polar bonding were the highest in Omicron spike-IgG interaction. Unlike other variants, both the L and H chains of the IgG interact with the N-terminal and C-terminal RBD of the S1-portion and partially bind to S2. In other cases, binding was observed in either NTD or CTD with a lesser number of bonding-interactomes, especially in Delta spike-Ab interaction. In the case of MHC class-II, the highest binding affinity/surface was noticed by omicron and least by the Delta variant. Better binding to the IgG and MHC molecules explains its lesser ability to immune invasion.
Hydrophobic Fluorescent Molecules in Multiple Organ Failure: a preliminary report.
Authors: Russo Luigi
Published: August 2022

Despite technological advances the mortality of Multiple Organ Failure MOF (or MODS) remains high. Liver is the main excretory organ for protein-bound toxins which accumulate in plasma of patients with hepatic failure. Hydrophobic molecules are present in plasma of patients with several toxic syndromes. Fluorescence is a characteristic of many aromatic compounds. Hydrophobic Fluorescent Molecules (HFM) in plasma have been studied in patients with MOF and hyperbilirubinemia. Heparinized venous plasma from 9 patients with MOF in post-operatory time (after cardiac surgery) was analyzed. All patients presented hyperbilirubinemia. One millilitre of plasma was extracted with 6 ml. of diethyl ether. Fluorescence of the ether fraction was determined with a digital filter fluorometer (excitation 300-400 nm. Emission >400 nm). Results were expressed in Fluorescence Arbitrary Units (A.U.). Control plasma were obtained from patients with chronic cardiac diseases; they had values mean 15 AU± 4,3 A.U. (range 11-21) of hydrophobic fluorescence. The mean Hydrophobic fluorescence of the MOF patients was 218.4 ± 276.3 A.U. (range 37-900). Data were highly significant (P<0.001).This preliminary study has shown that extremely high values of HFM are present in patients with hepatic failure and MOF. Hydrophobic molecules present a high inherent toxicity due to their insertion in the lipid bilayer of cell membranes and may be a determinant factor for the mortality of patients with MOF. The presence of specific HFM may be evaluated as a marker for prognostic purposes.
Effects of real-time remote cardiac rehabilitation on health and disability-related outcomes: a quasi-randomized controlled trial
Authors: Fukuta Yoshitatsu , Arizono Shinichi , Tanaka Shinichiro , Kawaguchi Tomonori , Tsugita Natsumi , Fuseya Takahiro , Magata Junichi , Tawara Yuichi , Segawa Tomonori
Published: August 2022

Background:The impact of real-time remote cardiac rehabilitation (CR) on health and disability-related outcomes and its correlation with physical function are unknown. We compared the effectiveness of real-time remote CR to that of hospital-based CR on the physical function improvement as well as physical functions of improvement (Δ) to clarify the relationship to health and disability for baseline.Methods:Patients with cardiovascular disease (CVD) were enrolled (n=38) in this quasi-randomized controlled trial and underwent 4 weeks of hospital-based CR, followed by 12 weeks of remote or hospital-based CR, based on quasi-randomized allocation. Patients were assessed at baseline and after 12 weeks of remote or hospital-based CR using the shortened version of the World Health Organization (WHO) Quality of Life scale (WHOQOL-BREF) for subjective satisfaction, WHO Disability Assessment Schedule (WHODAS2.0-J) for objective performance, and cardiopulmonary exercise test for physical function and peak oxygen uptake (peak VO2). The trends in measured variables from baseline to the post-CR stage were analyzed.Results:Sixteen patients (mean age, 72.2±10.4 years) completed remote CR, and 15 patients (mean age, 77.3±4.8 years) completed hospital-based CR. The post-CR physical function differed significantly between groups (ΔpeakVO2, 2.8±3.0 versus 0.84±1.8 mL·min-1·kg-1; p<0.05). The differences in post-CR changes in the WHOQOL-BREF score between the groups were insignificant. The post-CR change in the WHODAS2.0-J score was significantly lower in the remote CR group than in the hospital-based CR group (ΔWHODAS2.0-J score, –8.56±14.2 versus 2.14±7.6; p<0.01). Forward multiple stepwise regression analysis using data from remote CR showed that the baseline social interaction level (WHODAS2.0-J) was a significant independent contributor to ΔpeakVO2(remote CR r2=0.65, p<0.001; hospital-based CR r2=0.38, p<0.05; respectively). For hospital-based CR, baseline mobility (WHODAS2.0-J) was a significant independent contributor to ΔpeakVO2(r2=0.38, p<0.05).Conclusions:Remote CR significantly improved physical function and objective performance in patients with CVD. Remote CR could be an effective treatment for stable patients who are unable to visit hospitals.Trial Registration: This interventional trial was registered in the UMIN-CTR registry (trial title: Development of remote program for cardiac rehabilitation using wearable electrocardiograph; trial ID: UMIN000041746; trial URL: https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046564; registration date: 2020/09/09).
Four-Year Report on Renal Outcomes Following Elective Withdrawal of Long-Term RAAS Blockade in a Cohort of Patients with Otherwise Inexplicable New-Onset and Progressive Acute Kidney Injury
Authors: Amechi Macaulay
Published: August 2022

Background:
RAAS blockade is renoprotective for both diabetic and non-diabetic CKD. There have been discordant reports on renal and cardiovascular outcomes following RAAS blockade discontinuation in advanced CKD. To the contrary, a few prospective cohort studies have demonstrated reversal of otherwise inexplicable AKI in patients after discontinuation of RAAS blockade. This is a 4-year report of such a cohort.
Methods:
Prospective Cohort Analysis, enrolled between February 2018 – May 2021. Kidney function was monitored after elective withdrawal of long-term RAAS blockade in CKD patients presenting with new-onset otherwise inexplicable progressive AKI as defined by a > 25% increase in baseline serum creatinine.
Results:
By February 2022, 12 patients had died, and 8 patients were on hemodialysis for ESRD. The remaining 51 patients, with a baseline serum creatinine of 1.30 ± 0.42 (0.66–2.70) mg/dL, have been followed up for 706 (40-1478) days. Peak serum creatinine at study entry was 2.17 ± 1.06 (1.1–8.3) mg/dL, n = 51, P < 0.0001, t = 6.4872, df = 135. Serum creatinine, 48 months later, was 1.58 ± 0.54 (0.84–3.3) mg/dL, n = 50, p < 0.0001, t = 5.1805, df = 119. Death in 7 of 8 (87.5%) patients were from non-renal causes; most deaths occurred despite improved kidney function.
Conclusion:
Elective withdrawal of long-term RAAS blockade in CKD patients with new-onset progressive yet otherwise inexplicable AKI results in significant sustainable renal salvage. Such self-selected patients generally exhibit improved renal outcomes without increased mortality. This is consistent with late-onset renal failure from angiotensin blockade (LORFFAB), first described in 2005 from the Mayo Clinic Health System in Northwestern Wisconsin.