bluuebunny/crossref_metadata_2025 huggingface dataset:
Fermion with three mass parameters in the uniform magnetic field
Authors: Ovsiyuk E. , Safronov A. , Koral'kov A. , Voynova Ya.
Published: September 2023

Recently, models for a spin 1/2 particle with two (or three)

mass parameters were developed. Specific features of

these models are as follows. For corresponding two (or

three) bispinors in absence of external fields, separate Diraclike

equations are derived, they differ in masses. However,

in presence of external electromagnetic or gravitational

fields with non-vanishing Ricci scalar, the wave equation for

bispinors does not split into separated equations but makes

quite a definite mixing of two (or three) equations arises. In

the present paper, the model of a fermion with three mass parameters

is studied in presence of the external uniform magnetics

field. After performing a diagonalizing transformation,

three separate equations are obtained for particles with different

anomalous magnetic moments. Their exact solutions

and generalized energy spectra are found
Bragg’s reflections of a multilayer grating
Authors: Karpov A.
Published: September 2023

The reciprocal space of multilayer grating in the non-coplanar

geometry of diffraction is investigated. Direct and inverse relations

between the angles of wave vectors and coordinates of

reciprocal space are written out. The Bragg’s and diffraction

reflection angles are written. By example, cones of diffraction

and reciprocal space mapping are demonstrated.
THE DYNAMICS OF FAMILY-OWNED SME SUSTAINABILITY IN RURAL AREAS [DINAMIKA KEBERLANJUTAN UKM KELUARGA DI PEDESAAN]
Authors: Kusmulyono Muhammad Setiawan
Published: September 2023

SMEs in rural areas have characteristics that are closely related to the character of a family business. This can be seen in the management of the SME business which is fully controlled by the family. This situation shows that SMEs in rural areas are more dominated by family-owned SMEs. As a family-owned SME, this village entrepreneur has a big challenge to be able to regenerate the business for the next generation. This study seeks to identify the things that affect the dynamics in realizing the sustainability of family-owned SMEs in the village. This study uses a qualitative approach by conducting interviews through purposive sampling to culinary informants who run their businesses in rural areas and have the next generation. The results of the study show that in addition to all SMEs in the village being dominated by family businesses, these SMEs have hopes that their families will continue their business, but on the other hand it was also found that there are SMEs who do not care who will continue their business. This study produces interesting findings that can be developed to help improve the sustainability of SME development in Indonesia.

 

Abstrak dalam Bahasa Indonesia. UKM di pedesaan memiliki karakteristik yang erat kaitannya dengan karakter usaha keluarga. Hal ini terlihat dari pengelolaan usaha UKM yang sepenuhnya dikendalikan oleh keluarga. Keadaan ini menunjukkan bahwa UKM di pedesaan lebih didominasi oleh UKM milik keluarga. Sebagai UKM milik keluarga, pengusaha desa ini memiliki tantangan besar untuk bisa meregenerasi bisnisnya untuk generasi selanjutnya. Kajian ini berupaya mengidentifikasi hal-hal yang mempengaruhi dinamika dalam mewujudkan keberlanjutan UKM milik keluarga di desa. Penelitian ini menggunakan pendekatan kualitatif dengan melakukan wawancara melalui purposive sampling kepada informan kuliner yang menjalankan usahanya di pedesaan dan memiliki generasi penerus. Hasil kajian menunjukkan bahwa selain seluruh UKM yang ada di desa didominasi oleh usaha keluarga, UKM ini memiliki harapan agar keluarganya tetap melanjutkan usahanya, namun disisi lain juga ditemukan adanya UKM yang tidak peduli yang akan melanjutkan usahanya. Kajian ini menghasilkan temuan menarik yang dapat dikembangkan untuk membantu meningkatkan keberlanjutan pengembangan UKM di Indonesia.

 
Analisis Proses Rekrutmen pada PT. Kereta Api Indonesia Daerah Operasional 9 di Jember
Authors: Priawan Najunda Sari , Windradini Dwi , Suhartono Suhartono
Published: September 2023

This study aims to analyze the recruitment process carried out by PT. Kereta Api Indonesia DAOP 9 in Jember in order to meet the need for manpower. The method used is descriptive qualitative research by observing, interviewing, and direct documentation. The results of this study indicate that the recruitment process of PT. KAI is carried out by following the company's Workload globally. Recruitment conducted by PT. KAI is a process of fulfilling the need for workers in each branch office. Thus, in practice it does not prioritize the needs of each but prioritizes the needs of PT. Indonesian Railways as a whole. The implementation policy is carried out based on the results of the head office's considerations and decisions to obtain workers according to the existing qualifications and apply the same in each branch.
Alasan Singapura Memperpanjang Kontrak Pergelaran Formula 1 Grand Prix Tahun 2022
Authors: Rochmawati Ine Dwi
Published: September 2023

Singapore has renewed its Formula 1 Grand Prix contract in 2022 even though it has not benefited from the racing event for two years due to pandemic of Covid-19. This study aims to find out Singapore's reasons for extending the contract of the Formula 1 Grand Prix in 2022. This research uses qualitative methods. The theory of liberalism is used in this study to find out and understand Singapore's reasons for extending the 2022 Formula 1 Grand Prix contract. The result of this study is the Formula 1 Grand Prix Extention by Singapore is a form of the country’s nation branding efforts. Nation branding carried out by Singapore through the Formula 1 Grand Prix is divided into six aspects, namely tourism, cultural heritage, government, community, exports and investment. The success of nation branding in this event is the increase of country's image which is marked by the increase in foreign tourist visits to Singapore.
Strategi Tokoh Lokal melalui Komunitas Singo Gendeng dalam Memberdayakan Pengemis Anak
Authors: Restanti Fida Anisah , Gianawati Nur Dyah , Mayangsari Wahyuni
Published: September 2023

Beggars have become the main problem in various regions, especially in urban slum areas due to the poverty conditions in their environment. One of the villages located in the Talangsari area in the Jember Kidul Village, which is often stigmatized by the local community by the nickname "Beggar's Village" because many of its children beg. This moved one of the village's local leaders to carry out a strategy to empower village children through the Singo Gendeng Community. This community was established as a forum for educating traditional arts that were developed such as jaranan art, reog and so on with the aim that the habit of begging in children can be reduced and replaced with creativity and artistic skills. This research approach is qualitative with the type of research used is a case study. The technique of determining the informants and research locations is purposive. Data collection techniques include observation, interviews and documentation. The results of this study indicate a strategy carried out by local leaders through the Singo Gendeng Community in an effort to empower children to beg by fostering children's interest in art so that children are interested in participating in art activities. Besides that, it also cultivates potential and develops artistic talent in children through dance training activities, practicing playing musical instruments, performing and making crafts, so that their skills grow well.
Inovasi Proses Pelayanan Dokumen Kependudukan Terintegrasi di Dinas Kependudukan dan Pencatatan Sipil Kabupaten Sumenep
Authors: Ariska Novi Nur , Helpiastuti Selfi Budi , Suharsono Agus
Published: September 2023

This study aims to analyze the process innovation of integrated population documents at the Department of Population and Civil Registration of Sumenep Regency. The Department of Population and Civil Registration (Disdukcapil) of Sumenep Regency, as the implementing element of population administration services, still faces several problems due to the lengthy process of providing services. Therefore, Disdukcapil made an improvement by launching an integrated population document service innovation. This innovation brings new work processes or service procedures to make it easier and faster. This study aims to describe the innovation of integrated population document services at Disdukcapil, Sumenep Regency. The type of research used is the paradigm post-positivism with a qualitative approach. The data analysis used is interactive model data analysis. The results of this study indicate that the process innovation in the integrated population document service launched by the Sumenep Regency Disdukcapil is still not fully optimal, but there has been a renewal in the process innovation launched, as seen from the simplification of the service process offline and also the availability of servicesonline. It’s just that, in its implementation it still encounters several obstacles, including the service process in person online provided is still not able to be used properly by the island community because access to the internet network is still difficult to reach. In addition, there were complaints regarding the attitude of employees who were still considered unfriendly and lacking in discipline which contributed to suboptimal community satisfaction.
Blended Social Work Placements: New Opportunities
Authors: Beesley Paula , Taplin Sue
Published: September 2023

Social work student placements were significantly impacted over the past two years as a result of the Covid-19 pandemic, but a ‘new normal’ of placement provision has started to emerge. This conference paper provides reflections on the experiences of social work education providers, placement providers and practice educators on the new opportunities that have been created as a result of flexible responses to the changing landscape of blended placement provision necessitated by the pandemic, which were gathered at two international workshops held virtually at academic conferences in 2021. The workshops identified common responses from higher education institutes (Higher Education Institutions) and practice educators, where loss and change created the need for connectivity and flexible and creative solutions. This article will present the themes identified within the teaching partnership as well as findings from the two workshops to enhance understanding of the sustainability of blended social work placement provision.
Issues of Design and Construction of Bridge Structures for Domestic High-Speed Railways
Authors: Smirnov Vladimir
Published: September 2023

Purpose: The purpose is to highlight the state of the issue on the design and construction of domestic bridge structures for high-speed railways (HSR) and to develop proposals for structural and technical solutions for multi-span bridge structures of the overpass type, ensuring the operation of overpasses outside the resonance conditions. Methods: The method of analysis of structural and technological solutions of foreign bridge structures on HSR lines and design developments of domestic designers has been used. Results: The generalization of the world and domestic experience in the design and construction of the HSR infrastructure given in the article allows us to develop certain recommendations for the design and construction of bridge structures on the HSR in Russia. The relevance of the topic lies in the need to obtain data required for the construction of bridge facilities on the HSR in domestic conditions, since we do not have our own HSR yet. Practical significance: The article describes the design features of bridge structures on the HSR, the requirements for artificial structures operating in conditions of high-speed train traffic, describes bridge structures built abroad, as well as project and design developments of domestic design organizations. An assessment is given to some of the bridge facilities of the HSR built in Germany, South Korea, Spain. The high level of unique bridge structures of the HSR built in recent years in China is particularly emphasized. Proposals have been developed for structural and technological solutions of bridge multi-span regular structures in the form of overpasses based on the prevention of resonant effects in the “train — bridge” system during the movement of rolling stock at high speeds. The conclusion is made about the ability of the domestic bridge community to successfully solve the problems associated with the construction of bridge structures for domestic high-sp eed railways.
Accumulation of Heavy Metals in Soils and Phytomass in Urbanized Areas
Authors: Gavrilova Alina , Makarova Elena , Ahtyamov Rasul
Published: September 2023

Purpose: To carry out a qualitative and quantitative assessment of the content of heavy metals (Fe, Zn, Pb, Cd) in soils and aboveground vegetation organs of plants of the Olive family, namely the common lilac (Syringa vulgaris) growing in urban areas, using the example of the central part of the city of St. Petersburg. To assess the accumulation of iron, zinc, cadmium and lead by soil cover and phytomass, depending on the remoteness of the street-traffic network adjacent to garden-park areas, and the traffic intensity along the studied highways. Methods: The experimental method, based on the “Methodology for determining vehicle emissions for conducting summary calculations of urban air pollution”, has been used to determine the composition and traffic intensity of the traffic flow passing along highways adjacent to the study areas. Subsequently, the obtained data have been statistically processed. A total of 20 sampling points have been identified at the study sites, at different distances from the pollution source. Based on the adopted “Methodological guidelines for determining heavy metals in soils of agricultural lands and crop products”, samples have been taken and further sample preparation has been carried out for research by flame atomic absorption spectrometry. In the laboratory of the testing center “Ecological and Occupational Safety” of the Federal State Budgetary Educational Institution of Higher Education PGUPS, using the method of flame atomic absorption spectrometry, a quantitative analysis of the content of heavy metals (Fe, Zn, Pb, Cd) in selected soil and phytomass samples has been carried out. Results: The quantitative and qualitative composition of the intensity of the traffic flow passing through the central part of the city of St. Petersburg has been determined. The concentrations of heavy metals (Fe, Zn, Cd, Pb) have been determined in all selected soil samples and phytomass at the beginning and at the end of the growing season, leaves of common lilac shrubs growing in the central regions of the city of St. Petersburg. In most samples, elevated concentrations of heavy metals have been found in the aboveground vegetation organs of shrubs taken at the end of the growing season, compared with those taken at the beginning of the growing season. Practical significance: It is shown that the accumulation of heavy metals in plants and soil largely depends on the location of the pollution source and its intensity. The data obtained can be recommended for practical use.
Environmental Aspects in the Disposal of Used Coolants
Authors: Haritonenko Aleksandr , Solov'eva Valentina
Published: September 2023

Purpose: To consider the issue of the state of the problem of collection, disposal and impact of used coolants on the environment, primarily from road transport. To show the need for recycling of spent cooling liquids, the search for new compositions of cooling liquids and the intensification of the collection of spent antifreeze from the population. Methods: Comparing the characteristics of main coolants, highlighting their advantages and drawbacks on the stage of efficiency reduction. Analysis of the types of contaminants accumulating in spent antifreeze. Comparison of advantages and disadvantages of typical methods for purifying spent coolants. Analysis of the growth of sources of anthropogenic impact in the considered area. Results: The most important characteristics of coolants have been established. The most characteristic types of contaminants contained in antifreeze are identified and the most suitable methods of their regeneration are given. The high relevance of the considered problem of the circulation of spent antifreeze as a result of the rapid growth of motorization of the population in the absence of proper control by the state is noted. The necessity of searching for new safe antifreezes while maintaining the target qualities of coolants is revealed. Practical significance: The necessity of revising the attitude to antifreeze in terms of assessing their danger to the environment is shown. The ways of improving the handling of waste coolant solutions in terms of intensifying their collection from enterprises and the public are outlined. It has also been noted that it is necessary to search for new solutions of cooling liquids with a lower content of harmful substances in them to protect humans and the environment.
The Algorithm for Evaluating the Publication Activity of University Lecturers Aimed at Improving Scientific and Pedagogical Activity
Authors: Gerasimenko Petr
Published: September 2023

Purpose: To create a more effective algorithm for evaluating the publication activity of lecturers in comparison with the existing algorithms for the formation of the Hirsch index and ghp-index. Methods: The algorithm includes a mathematical description of all published works of the lecturer and their citations. The results of the scientific activity of the lecturer are reflected using the matrix form of recording statistical source data, consisting of citations for each published work of the author. The sequence of citations of publications in the matrix is determined by the non-increasing nature of citations in subsequent publications compared to the previous ones. The constructed matrix of the distribution of citations S by published works is rebuilt into a block matrix, which includes the following block matrices: H is the base matrix defining the Hirsch index; G is the matrix of significant publications located above the Hirsch matrix; P is the matrix of less-cited works of the lecturer; O is the zero matrix. The formed matrices have allowed the introduction of the following indices using Euclidean norms: h — Hirsch index, g — index of significant publications and p — index of intensive work. In turn, these indices have allowed to determine the following as Euclidean norms: gh — the index of basic significant publications, hp — the index of intensive work of a lecturer and a comprehensive ghp-index that takes into account all the published works of a lecturer and all their citations. The ghp-index has been improved by introducing weighting coefficients for its constituent indices. Results: The ratings of a team of 20 lecturers has been formed using a sample from the RSCI with the help of the Hirsch index and the A-ghp index. It is shown that the proposed algorithm is more effective in comparison with the Hirsch index and other introduced indexes. Practical significance: The conducted research has allowed to substantiate the possibility of using an improved comprehensive index to distribute the incentives of a team of lecturers in a differentiated and fair manner according to their rating. The algorithm aims to improve the scientific and methodological activities of lecturers by providing fair and accurate ranking of the members of their collectives.
The Effect of Google Classroom Media Utilization in Physics Learning on Students' Interest and Learning Outcomes at SMA Negeri 9 Kendari
Authors: Isa La , Santri Santri , Zainuddin Zainuddin , Asmin La Ode , Santri Dewi
Published: September 2023

This study aims to determine the effect of Google Classroom media utilization in learning Physics on students' interest and learning outcomes at SMA Negeri 9 Kendari. The method used in this research is an ex post facto survey with a quantitative approach. The data analysis technique used is path analysis with the help of Smart-PLS software at α = 5%. Based on the study results, it is concluded that the utilization of Google Classroom is classified in the excellent category with a percentage figure of 69.59%. Learning interest is organized in a strong class with a percentage rate of 75.55%. Learning outcomes are classified in the moderate category with an average acquisition value of 73.62 and a percentage rate of 100% of students meeting the minimum completeness criteria (KKM). Google Classroom utilization (X) significantly affects learning interest (Y1) by 0.559. Google Classroom utilization can explain/contribute to students' physics learning outcomes by 13%. Google Classroom utilization (X) has a significant indirect effect on learning outcomes (Y2) through learning interest (Y2) of 0.240. Google Classroom utilization can explain/contribute to students' physics learning outcomes.
Relación entre ausencia de células endocervicales y citología Papanicolaou negativa en portadoras de lesiones escamosas premalignas de cuello uterino
Authors: Centeno-Díaz Roger
Published: September 2023

Objetivo: Determinar la relación entre la ausencia de células endocervicales y resultados citológicos Papanicolaou falsos negativos. Material y métodos: Estudio observacional, de enfoque cuantitativo, transversal, relacional y retrospectivo realizado en el Servicio de Anatomía Patológica del Hospital General de Huacho. Se realizó la búsqueda de resultados de biopsias de cuello uterino positivos para lesiones intraepiteliales escamosas y sus respectivos resultados citológicos Papanicolaou previos durante los años 2016 al 2018. Se seleccionó los resultados negativos con ausencia de células endocervicales. Resultados: De los 158 resultados citológicos, 23 mostraron ausencia de células endocervicales y de éstos, sólo dos (8,7%) fueron reportados como negativos. En total 11 (7%) citologías fueron negativas. Conclusiones: No se encontró relación entre la ausencia de células endocervicales y resultados citológicos falsos negativos; por tanto, no influyó de manera significativa en la detección de lesiones escamosas premalignas de cuello uterino.
KNOWLEDGE AND ATTITUDE OF FARMERS TOWARDS ANTIMICROBIAL RESISTANCE IN ASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Mikail Athif Zhafir Asyura Muhammad , Angela Novia
Published: September 2023

Background: Antimicrobial resistance is a severe threat to public and environmental health. The agricultural sector contributes significantly to resistance, where antimicrobials are used as prophylaxis, growth promoters, and for treatment. A series of studies have been conducted to assess farmers' knowledge and attitude levels with varying results, particularly in Asia, one of the world's largest producers of livestock products. Purpose: To review the pooled estimated level of knowledge and attitude towards antimicrobial use and resistance in Asia. Methods: A literature search was conducted according to PRISMA in Scopus, PubMed, Google Scholar, and Embase for studies up to 30 April 2023. Quality was assessed using the Newcastle-Ottawa Scale (NOS) for cross-sectional studies. Outcomes were further categorized into constructs under knowledge and attitude. Random-effect meta-analysis was conducted using STATA 17. Results: 11 studies and 2131 subjects were included with fair to excellent quality. From the meta-analysis, the following knowledge and attitude levels were estimated: definition [55.7% (95%CI: 37.3%-74%)] and cause [60.6% (95%CI: 40.5%-80.6%)] of antimicrobial resistance; the negative impact of antimicrobials [62.6% (95%CI: 16.9%-100.0%)]; use of antimicrobials for treatment [47.8% (95%CI: 6.1%-89. 4%)], prophylaxis [58.5% (95%CI: 28.5%-88.5%)], growth promoter [39% (95%CI: 23.1%-54.9%)]; discontinuation of antimicrobials upon improving conditions [42.5% (95%CI: 15.4%-69.5%)]. Conclusions: Farmers in Asia have moderate knowledge of antimicrobial resistance but still exhibit attitudes that support resistance.
Teknik Self-Management untuk Menurunkan Perilaku Membolos pada Siswa Kelas XI
Authors: Rahma Eriska , Oktavia Citrawanti , Sholichah Ima Fitri
Published: September 2023

This study aims to determine the effect of self-management techniques on students' behaviour. This research was carried out on class XI students in Islamic high school. This study uses one pretest-posttest design group without comparison groups or control groups, the population employed by class XI IA. A total of 5 students obtained as many as four students. Sampling using a purposive sampling technique. Data collection methods use trooting behaviour questionnaires. Data analysis techniques use parametric paired sample t-test analysis. The results of the study. It shows that self-management techniques reduce the behaviour of skipping students. This is evidenced by the difference in lowering behaviour of diving between the pre-test and post-test results, where the average post-test results are lower than the pre-test results after a self-management technique is given. Based on the results of the pre-test and the existing post-test showed a change in the behaviour. Who experienced a decrease in the conduct of skipping after individual counselling using the behaviour approach with self-management techniques            
Public Insurance and Single-Guardian Households Are Associated with Diagnostic Delay in Slipped Capital Femoral Epiphysis
Authors: Smith Lacey M. , Chang Yuchiao , Feldman Candace H. , Santacroce Leah M. , Earle Madison , Katz Jeffrey N. , Novais Eduardo N.
Published: September 2023

Background:

Extensive literature documents the adverse sequelae of delayed diagnosis of slipped capital femoral epiphysis (SCFE), including worsening deformity and surgical complications. Less is known about predictors of delayed diagnosis of SCFE, particularly the effects of social determinants of health. The purpose of this study was to evaluate the impact of insurance type, family structure, and neighborhood-level socioeconomic vulnerability on the delay of SCFE diagnosis.

Methods:

We reviewed medical records of patients who underwent surgical fixation for stable SCFE at a tertiary pediatric hospital from 2002 to 2021. We abstracted data on demographic characteristics, insurance status, family structure, home address, and symptom duration. We measured diagnostic delay in weeks from the date of symptom onset to diagnosis. We then geocoded patient addresses to determine their Census tract-level U.S. Centers for Disease Control and Prevention (CDC) and Agency for Toxic Substances and Disease Registry (ATSDR) Social Vulnerability Index (SVI), using U.S. Census and American Community Survey data. We performed 3 separate logistic regression models to examine the effects of (1) insurance status, (2) family structure, and (3) SVI on a delay of ≥12 weeks (reference, <12 weeks). We adjusted for age, sex, weight status, number of siblings, and calendar year.

Results:

We identified 351 patients with SCFE; 37% (129) had a diagnostic delay of ≥12 weeks. In multivariable logistic regression models, patients with public insurance were more likely to have a delay of ≥12 weeks than patients with private insurance (adjusted odds ratio [OR], 1.83 [95% confidence interval (CI), 1.12 to 2.97]; p = 0.015) and patients from single-guardian households were more likely to have a delay of ≥12 weeks than patients from multiguardian households (adjusted OR, 1.95 [95% CI, 1.11 to 3.45]; p = 0.021). We did not observe a significant increase in the odds of delay among patients in the highest quartile of overall SVI compared with patients from the lower 3 quartiles, in both the U.S. comparison (adjusted OR, 1.43 [95% CI, 0.79 to 2.58]; p = 0.24) and the Massachusetts comparison (adjusted OR, 1.45 [95% CI, 0.79 to 2.66]; p = 0.23).

Conclusions:

The delay in diagnosis of SCFE remains a concern, with 37% of patients with SCFE presenting with delay of ≥12 weeks. Public insurance and single-guardian households emerged as independent risk factors for diagnostic delay. Interventions to reduce delay may consider focusing on publicly insured patients and those from single-guardian households.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Disfemisme Warganet dalam Kolom Komentar Media Sosial Instagram @Kpipusat (Kajian Semantik)
Authors: Selgianita Riska , Antono Mixghan Norman
Published: September 2023

Athere is the use of abusive language or dysphemism on Instagram social media by netizen. Instagram @kpipusat is a social media agency for the Indonesian broadcasting commission has been found in the comments column. The purpose of the research is to (1) describe the language of netizen dysphemism in the comments column of social media Instagram @kpipusat. (2) describe the fuction of netizen dysphemism in the comments column of social media Instagram @kpipusat. The reseacrh approach uses a descriptive qualitative approach. The object of this research is the language of dysphemism in the comments column of social media Instagram @kpipusat. The data collection technique in this research is the free listening technique, the conversational involvement and the note taking technique. The result of this study indicate that there are (1) dysphemism language found were words with a total of 21 data, then prases with 5 data and sentences with 4 data. (2) function of dysphemisme on the use is as follows: (1) to describe taboo or indencent things, (2) to describe dislike or hata. (3) to describe insulting or reproaching and ridiculing, (4) to describe someone’s negative, and (5) to describe cursing someone. There are 23 data of dysphemime function.
Pengaruh Penggunaan Media Gambar Berseri Berbasis Digital Bertema Sosial Terhadap Keterampilan Menceritakan Kembali Teks Fabel Siswa Kelas VII MTS Al-Hikmah Purwoasri Kabupaten Kediri
Authors: Wahyuni Laila , Farahiba Ayyu Subhi
Published: September 2023

This research is motivated by the tendency of teachers to use the old approach or simply convey theory which results in students being less actively involved in the teaching process. The purpose of this study was to determine the effect of using social-themed digital serial media images on the skills of retelling fable texts for class VII students of MTs Al-Hikmah Purwoasri, Kediri Regency. This type of research is a quantitative research with a quasi-experimental method with a non-equivalent group design. Sampling technique with purposive sampling. The sample in this study is the control class and the experimental class. The variables in this study are independent variables, dependent variables, and control variables. The data of this study is the skill test scores of retelling fable texts without and by using social-themed digital serial media images. The results of this study were the mean scores for the control and experimental pretest classes, namely 61.25 and 68.5, the control and experimental posttest classes, namely 73.25 and 81.5. Processing the t-test with the condition that the two samples must be normally distributed and the variance is homogeneous. The posttest t-test results obtained from the control and experimental classes were tcount 3.535 and ttable 2.024. The condition for the t-test is that if tcount ttable then Ho is rejected. So, there is a significant influence on social-themed digital-based serial image media on the skills of retelling fable texts for class VII MTs Al-Hikmah Purwoasri, Kediri Regency.
Frasa Endosentris Atributif dalam Bahasa Madura Dialek Bangkalan: Analsisi Morfo-Sintaksis
Authors: Haryono Alib Tegar , Lutfitasari Wevi
Published: September 2023

Analisis morfosintaksis bertujuan untuk mengetahi hubungan antara morfologi dengan sintaksis, salah satunya pada fenomena frasa endosentris atributif dalam Bahasa Madura dialek Bangkalan. Data penelitiannya berupa frasa atributif yang muncul pada interaksi antara penjual dan pembeli di pasar. Frasa endosentris tersebut dipengaruhi oleh dialek Bangkalan yang menghilangkan fonem vokal dan memunculkan konsonan rangkap. Frasa endosentris yang muncul berupa frasa nomina, verba, numeralia, interogatif, adjektival, adverbia, pronomina, interogatif, dan demonstrative. Fungsi dari penggunaan frasa yang terpengaruh oleh dialektologi adalah untuk memperjelas suatu kategori kata dalam sebuah kalimat. Kategori kata tersebut yaitu kata kerja, kata benda, kata sifat, kata bilangan, kata ganti benda, kata keterangan, kata tanya dan kata ganti petunjuk.
Stereotip Tokoh Yuni dalam Film Yuni Karya Kamila Andini
Authors: Oktavia Risma , Faqih Fiyan Ilman
Published: September 2023

Stereotip pada perempuan sering terjadi pada lingkungan masyarakat, stereotipe atau anggapan buruk terhadap perempuan dapat merugikan kaum perempuan di segala bidang. Tujuan dari penelitian ini untuk mendeskripsikan bagaimana bentuk ketidakadilan gender stereotip pada tokoh Yuni dalam film Yuni karya Kamila Andini. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Objek penelitian ini berasal dari film Yuni karya Kamila Andini. Prosedur penelitian yang dilakukan dengan tahap persiapan, tahap pelaksanaan, dan tahap akhir. Data yang dianalisis berdasarkan reduksi data, penyajian data, dan penarikan simpulan. Uji keabsahan data dalam penelitian ini menggunakan ketekunan pengamatan dan uraian rinci. Hasil penelitian ini menunjukkan bahwa stereotip yang dialami pada tokoh Yuni dalam film Yuni karya Kamila Andini yaitu ketika perempuan dianggap buruk oleh masyarakat karena hamil di luar nikah, perempuan dilarang untuk menolak lamaran sebanyak dua kali, perempuan juga identik dengan sosok yang anggun sehingga harus memakai perhiasan dan yang terakhir yaitu ketika pendidikan untuk perempuan menjadi nomor dua karena tugas utama perempuan setelah lulus sekolah yakni hanya untuk melayani suami dan anak-anaknya.Kata kunci: Stereotip, Film, Perempuan
Eksistensi Tokoh Perempuan pada Antologi Cerpen Paraban Tuah Karya Elok Teja Suminar (Kajian Feminisme Eksistensialis)
Authors: Setianingsih Yenny , Ikhwan Wahid Khoirul
Published: September 2023

This study describes the existence of female characters in the short story anthology Paraban Tuah by Elok Teja Suminar using the theory of existentialist feminism from Simone De Beauvoir, including her condition and existence. The problem under study is: how is the existence of female characters in the short story anthology Paraban Tuah by Elok Teja Suminar based on Simone De Beauvoir's existentialist feminism? The purpose of this research is to describe the form of existence of female characters in the anthology of short stories Paraban Tuah by Elok Teja Suminar based on existentialist feminism. This research approach uses a qualitative descriptive method. The research subjects were people who were informants in the study, including the researcher herself and the female Madurese character in the short story anthology Paraban Tuah. The collection technique is using library techniques, reading techniques, and note-taking techniques. The research instrument lies with the researcher himself using note-taking techniques in the form of a data corpus. The results of research on the existence of female characters in the short story anthology Paraban Tuah by Elok Teja Suminar obtained 88 data from 11 short stories, including the existence of female characters in subject-object relations, in the realm of marriage as (child, wife, and mother), the existence of female characters which involves her body as a power of perception and as an obstacle, as well as a form of transcendence of female characters, namely work and intellectuality.
Cellular and Molecular Characterization of CADASIL Using In Vitro Models of Vascular Smooth Muscle Cells and Blood Vessel Organoids
Authors: Do Jeong Tae , Lee So Been , Nam Hyo Suk , Oh Seungyeon , Na Seungbin , Kim Hyun Kyu , La Hyeonwoo , Lee Man Ryul , Hong Kwonho
Published: September 2023

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common inherited form of stroke, characterized by a NOTCH3 mutation on chromosome 19. Despite many genetic and functional studies, the exact mechanisms and pathologies have not been fully elucidated. Herein, the cellular and molecular characteristics of vascular smooth muscle cells (VSMCs) and constituent cells of blood vessel organoids are investigated. Fibroblasts derived from a patient with CADASIL are reprogrammed into iPSCs and differentiated into VSMCs, cerebral organoids, and blood vessel organoids. In CADASIL iPSC-derived VSMCs, NOTCH3 extracellular domain antibody is detected. In CADASIL-blood vessel organoids, significant differences in the blood vessel related parameters between CADASIL and control blood vessel organoids are found. Additionally, cerebral organoids by CADASIL-iPSCs are distinct from those by control-iPSCs. Furthermore, based on RNA sequencing, differentially expressed genes between control and CADASIL samples are associated with proliferation rate, cell cycle, and nuclear division in VSMCs and angiogenesis and vasculogenesis in blood vessel organoids. Six distinct clusters in blood vessel organoids and cell proportion differences between control and CADASIL are identified using single-cell RNA sequencing. This study highlights CADASIL VSMCs and 3D organoids may facilitate investigating molecular and cellular mechanisms underlying CADASIL pathogenesis.
Development and validation of a nomogram to predict the risk of postmenopausal uterine leiomyoma degeneration: A retrospective study
Authors: WANG Yaping , Zhao Yiyi , Shi Chaolu , Li Juanqing , Huang Xiufeng
Published: September 2023

Objective: The aim of this study was to investigate the risk factors for postmenopausal uterine leiomyoma degeneration and to develop a nomogram for clinical risk assessment.
Study design and setting: A total of 508 patients were enrolled from 1 August 2012 to 1 August 2022. Univariate and multivariate logistic regression models were used to analyse the association between variables and uterine leiomyoma degeneration in postmenopausal patients. A nomogram for uterine leiomyoma degeneration in postmenopausal patients was developed and validated by bootstrap resampling. The calibration curve was used to assess the accuracy of the model and the ROC, DCA and NRI were compared with the clinical experience model.
Results: DM, breast cancer, number, size5, LDH, TG and Ca2+ were independent risk factors for uterine leiomyoma degeneration in postmenopausal patients. We developed a user-friendly nomogram which showed good diagnostic performance (AUC=0.714). The model was consistent and the calibration curve of our cohort was close to the ideal diagonal line. DCA indicated that the model has potential value for clinical application. Furthermore, our model was superior to the previous clinical experience model in terms of ROC (P=0.00039), DCA and NRI (NRI=0.4175722).
Conclusions: We have developed a prediction nomogram for uterine leiomyoma degeneration in postmenopausal patients. This nomogram could serve as an important warning signal and evaluation method for the degeneration and malignant transformation of uterine leiomyoma in postmenopausal patients.
Comparative study of the corneal morphological characteristics of keratoconus evaluated using CASIA2, Sirius, and Pentacam
Authors: Zhou Xingtao , Sun Bingqing , Hu Xiaojun , Peng Xiaoliao , Ten Weijung , Huang Yangyi , Sun Ling , Zhang Xiaoyu
Published: September 2023

Purpose
To analyze the corneal morphology of keratoconus using CASIA2, Sirius, and Pentacam.
Methods
Patients diagnosed with keratoconus at the Eye and ENT Hospital of Fudan University (January-November 2022) were included. Corneal refraction, astigmatism, thickness, and elevation parameters were measured using CASIA2, Sirius, and Pentacam. The measurement differences, agreement, and the sensitivity and specificity of each instrument for diagnosing keratoconus was evaluated. P < 0.05 was considered statistically significant.
Results
A total of 61 keratoconus eyes and 48 healthy myopic eyes were included. The Ks and Kf measured using Sirius were the highest (p < 0.0001). The thinnest corneal thickness measured using Pentacam was the thickest (p < 0.0001); however, the significance disappears in the Kmax ≤ 48D keratoconus group. When the best fit sphere was based on CASIA2, the anterior and posterior elevations at thinnest points measured using Sirius were the highest in keratoconus group and the lowest in control group. Corneal refractive power measurements significantly differed among instruments (p < 0.0001). In the control group, the agreement limits for total corneal refractive power (TCRP), fKm, and pKm were lower and narrower than in keratoconus. In keratoconus group, Pentacam and CASIA2 showed the best consistency in the measurement of TCRP and fKm, whereas Pentacam and Sirius showed the best consistency in the measurement of pKm. Sensitivities for diagnosing keratoconus ranked from high to low: Pentacam, CASIA2, Sirius (p < 0.0001).
Conclusion
CASIA2, Sirius, and Pentacam exhibit differences in corneal elevation, refractive power, and thickness measurements, with poor consistency in refractive power measurement.
Fully automated 4D cardiac modelling from 2D echocardiography for clinical applications
Authors: Laumer Fabian , Rubi Lena , Matter Michael , Buoso Stefano , Fringeli Gabriel , Mach Francois , Ruschitzka Frank , Buhmann Joachim , Matter Christian
Published: September 2023

Transthoracic Echocardiography (TTE) is a crucial tool for assessing cardiac morphology and function quickly and non-invasively without ionizing radiation. However, the examination is subject to intra- and inter-user variability and recordings are often limited to 2D imaging and assessments of end-diastolic and end-systolic volumes. Current 3D TTE is time-consuming and provides lower image quality than 2D TTE. We have developed a novel, fully automated machine learning-based framework to generate a 4D (3D plus time) personalized model of the left ventricular (LV) blood pool. This digital twin was generated from specific 2D echocardiographic views employing deep neural networks, pre-trained on a synthetic dataset, and fine-tuned in a self-supervised manner using a novel optimization method for cross-sectional imaging data. This 4D model enabled detailed three dimensional analyses of LV systolic and diastolic function with high temporal resolution. Validation was performed on a multi-center dataset encompassing TTE exams of 144 patients with normal TTEs (controls) and 314 patients with acute myocardial infarction (AMI). LV volume measurements in controls derived from the digital twin showed a high correlation with the values from the clinical TTE reports (Pearson correlation coefficient of 0.7). In AMI patients, these novel biomarkers showed a high predictive value for survival (area under the curve (AUC) of 0.82 for 1-year all-cause mortality) and and excellent diagnostic value for infarct localisation and quantification, bearing the potential to improve diagnostic accuracy and risk assessment. Thus, our digital twin allows for fully automated robust LV shape analyses over time including contractility, relaxation, and regional wall motion abnormalities aiming at replacing expensive 3D imaging modalities with cheaper and more versatile 2D cardiac ultrasound.
Efficacy of four indigenous Penicillium fungal isolates and Aspergillus fumigatus on Fusarium oxysporum f.sp. radicis lycopersici (FORL)
Authors: Ramachela Khosi , Ramatsitsi Mukondeleli Ndivhuwo , Segone Galaletsang Petronella
Published: September 2023

In search for indigenous soil borne fungi with bio-control properties against plant pathogenic F. oxysporum f.sp. radicis-lycopersici (FORL) resulted in the isolation of five fungal species. These were identified as: Penicillium commune-1 (MK660351.1), P. commune-2 (MK660335.1), Aspergillus fumigatus (MN178806.1), P. concavorugulosum-1 (MK841454.1) and P. concavorugulosum-2 (MK841454.1). An in vitro dual culture plate experiment was carried out to assess radial growth inhibition and growth competitiveness of potential antagonism on FORL. Analysis of the fungal bio-agents’ interactions with FORL showed occurrence of various relationships such as antibiosis, competition and mycoparasitism. High inhibition effect of P. concavorugulosum-2 (67.9%) and A. fumigatus (65.36%) against FORL was established. The other test isolates’ inhibition was not significant as they ranged from 9–29%. A conclusion can be drawn that P. concavorugulosum-2 and A. fumigatus contain potential bio-antagonistic properties that suppressed of growth of FORL. These fungal isolates should be considered as good candidates for development as commercial bio-control agents as individuals or in combination. However, these species’ suppressive properties should be evaluated under natural soil conditions where various biotic and abiotic factors could influence the efficacy.
Third-Party Cytotoxic T Lymphocytes for High-Risk Patients with Covid-19
Authors: Grosso Dolores , Wagner John , O'Connor Allyson , Keck Kaitlyn , Huang Yanping , Wang Zi-Xuan , Mehler Hilary , Leiby Benjamin , Flomenberg Phyllis , Gergis Usama , Nikbakht Neda , Morris Michael , Karp Julie , Peedin Alexis , Flomenberg Neal
Published: September 2023

Treatment with off-the-shelf cellular therapy may provide direct and rapid treatment for COVID-19, overcoming the delayed adaptive immune responses associated with poor outcomes in high-risk patients. Thirty ambulatory patients with COVID-19 were enrolled on a phase I trial to assess the safety of 3rd party, COVID-19-specific cytotoxic T lymphocytes (CTLs). Twelve “Interventional” patients matching the HLA-A*02:01 restriction of the CTLs received a single infusion of one of four escalating doses of a product containing 68.5% COVID-19-specific CD8+ CTLs/total cells. Eighteen “Observational” patients lacking HLA-A*02:01 served as comparisons. No dose-limiting toxicities were observed. Nasal swab PCR data showed ≥ 88% viral elimination in 92% of patients in 4 days and the CTLs remained detectable at 6 months. Interventional patients consistently reported symptomatic improvement 2-3 days after infusion, whereas improvement was more variable in Observational patients. Our study shows that COVID-19-specific CTLs are a potentially useful cellular therapy for COVID-19.
Opioid induced hyperalgesia treated with low dose naltrexone improves pain
Authors: Johnson Brian , Zhang-James Yanli
Published: September 2023

Opioids are prescribed for 5 – 8 million Americans with chronic pain1 and many more worldwide. For patients currently on chronic opioid therapy (COT) continuation of opioids is recommended because of mental health crises and overdoses that occur during medication taper2 and because of deaths associated with accidental overdose when opioid medications are discontinued.3, 4 Because opioid medications are exogenous opioid hormones that downregulate the pain damping opioid receptor system and upregulate pain drivers, opioid induced hyperalgesia (OIH) is a near-universal finding when the cold pressor test (CPT) is used to measure pain tolerance.5 Detoxification is best accomplished with a single dose of buprenorphine immediately followed with low dose naltrexone (LDN). LDN treats OIH.
We conducted a retrospective chart review of patients treated on our pain service from 2011 through 2022. Short CPTs improved with detoxification and LDN. Pain diminished.
Our results show that opioid medications are contraindicated for chronic pain. Patients currently prescribed daily opioid medications can safely be detoxified and have their centrally mediated pain treated with LDN, using the CPT to track resolution of OIH. Psychotherapy is necessary in many instances because opioids attenuate feelings and distort relationships.