bluuebunny/crossref_metadata_2025 huggingface dataset:
A Duplex SYBR Green I-based Real-time Polymerase Chain Reaction Assay for Rapid Detection of Canine Kobuvirus and Canine Circovirus
Authors: Pan Yang , Chen Jing , Wu Junhuang , Wang Yongxia , Zou Junwei , Yu Ju , Xu Fazhi , Wang Yong
Published: December 2021

Background: Canine Kobuvirus (CaKoV) and Canine Circovirus (CaCV) are viruses that infect dogs causing diarrheal symptoms that are very similar. However, there is no clinical method to detect a co-infection of these two viruses.Results: In this study, a duplex SYBR Green I-based quantitative real-time polymerase chain reaction (PCR) assay for the rapid and simultaneous detection of CaKoV and CaCV was established. CaKoV and CaCV were distinguished by their different melting temperature which was 86℃ for CaKoV and 78℃ for CaCV. The assay was highly specific, with no cross-reactivity with other common canine viruses and demonstrated high sensitivity. The detection limits of CaKoV and CaCV were 8.924 × 101 copies/μL and 3.841 × 101 copies/μL, respectively. The highest intra- and inter-assay Ct value variation coefficients (CV) of CaKoV were 0.40% and 0.96%, respectively. For CaCV, the highest intra- and inter-assay Ct value variation coefficients were 0.26% and 0.70%, respectively. In 57 clinical samples, positive detection rates of CaKoV and CaCV were 8.77% (7/57) and 15.79% (9/57), respectively. The co-infection rate was 7.02% (4/57). Conclusions: The duplex SYBR Green I-based real-time PCR assay established in this study is a fast, efficient, and sensitive method for the simultaneous detection of the two viruses and provides a powerful tool for the rapid detection of CaKoV and CaCV in clinical practice.
Thermophysical and Transport Properties of the BaCl2-CsCl High Temperature Ionic Liquid Mixtures
Authors: Popescu Ana-Maria , Constantin Virgil
Published: December 2021

High temperature ionic liquids (HTILs) densities and transport properties for mixtures BaCl2‑CsCl, x(BaCl2) = 0-1, have been studied as a function of composition and temperature. In terms of Arrhenius theory, the temperature correlation of all measured properties was made and discussed. Thermodynamic properties (isothermal compressibility, molecular volume, lattice energy, heat capacity, molar Gibbs energy, enthalpy and entropy) were derived for all the studied HTILs from experimental data. The viscosity isotherms show negative deviations from linearity, while conductivity isotherms have positive deviations which may be related to the formation of highly negative changed ion associated species. The evolution of the excess quantities: viscosity deviation (Δη), excess molar viscosity (ΔEη), excess molar conductivity (ΔEκ), show a very good parallelism. The linear behavior between conductivity and viscosity was determined using the fractional Walden rule and the average slope was found far from unity.
Kuzbass Strategy over 50-year Planning Horizon: Publications on Strategy of the Kuzbass Region
Authors: Kvint Vladimir , Astapov Kirill
Published: December 2021

Over its 300-year history, the Kuzbass Region has become one of the strongest industrial and coal mining areas. However, new environmental requirements stipulated by the Paris Agreement and the EU Energy Strategy require a new diversified and innovative economy, i.e. comfortable conditions for people to live and do business. The Strategy for Socio-Economic Development of Kuzbass through 2035 was approved by Regional Law No. 163‑OS on December 23, 2020. The Strategy covers human capital, ecology, reclamation water resources, digitalization, economy, investment, tourism, exhibitions, etc. All these aspects are highlighted in the monographs of the Strategy of the Kuzbass Region. The publications prove that a long-term strategy should combine traditional and novel competitive advantages of the region, which include hydrogen cluster, transport infrastructure, digitalization of business and other spheres, better environmental conditions, forest and land reclamation, sustainable use of water resources, as well as the importance of rebranding the region on the domestic and international arena.
Diagnosing the Business Development during Strategizing
Authors: Kalinskiy Oleg , Isaeva Nadezhda
Published: December 2021

Introduction. As a rule, strategic plans use the potential plant capacity to adapt the enterprise to adverse conditions, and these plans require constant adjustment. Strategic plans that rely on insufficient information about pant capacity may result in significant financial losses for the company. The research objective was to develop a principle for diagnosing sustainable growth based on potential capacity. Study objects and methods. The research featured three metallurgical enterprises, since metallurgy is of strategic importance for the domestic industrial development. The study involved such standard methods as system and situational analysis, expert assessments, correlation analysis, regression analysis, topological analysis, and statistical simulation. Results and discussion. The authors proposed an algorithm for calculating three types of potential capacity indicators: relative added value and revenue (y1), situational potential (y2) and performance (y3). The new methods made it possible to forecast the indicators of sustainable development and compare the mode of operation with standard value, i.e. the length of the estimated vector, which exceeded or equaled a certain fraction of its maximum possible value. If the vector length was less than this value, the stability started to decrease. The performance indicator demonstrated if the enterprise reached the maximal value of the indicator when it exceeded the boundary of the sustainability standard. Conclusion. The new approach provided a prompt assessment and forecast of the potential plan capacity. It could improve the forecast of potential instability, increase the flexibility of strategic plans, and prevent strategic shock.
USE OF TELEMEDICINE METHODS AND MEANS OF IMAGE INFORMATION ACQUISITION FROM COSMONAUTS
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Orlov O.I. , Popova I.I. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Reviakin Yu.G. ,   Keldysh Institute of Applied Mathematics of the Russian Academy of Sciences, Moscow
Published: December 2021

Telemedicine potential in informational support to the biomedical monitoring of Russian crewmembers at the International space station (ISS) is illustrated by experiment BIMS aimed to demonstrate platforms TBK-1 and TBK-1S developed for acquisition and processing of dental, otholaryngological and dermatological images. The paper presents the procedure and results of detailed oral mucosa and teeth examination with the use of TBK-1S, and deliberates on desirable improvements of the on-board telemedicine practice.
CORRELATION BETWEEN INCIDENCE OF X-MONOSOMY AND COSMIC BACKGROUND RADIATION
Authors:   Semmelweis University Medical School, Budapest, Hungary, Beke A. , Erdős G. ,   Institute for Particle and Nuclear Physics, Wigner Research Centre for Physics, Hungarian Academy of Sciences, Budapest, Hungary
Published: December 2021

Objective: Examining the incidence of X-monosomy among chromosomal aneuploidies with relation to cosmic background radiation. Method: We have processed the results of prenatal chromosome investigations performed in the 26-year period between 1990 and 2015. In the current study, we have paid special attention to abnormalities affecting the fetal sex chromosomes. The incidence of X-monosomy among sex chromosomal aneuploidies was studied in view of the intensity of cosmic background radiation. Results: In the 26-year period total of 43,272 fetal chromosomal investigations were carried out at our Department. In that period, sex chromosomal abnormality was detected in 230 cases (0.53 %), 92 of which (0.21 %) turned out to be X-monosomies. An uneven incidence ratio of X-monosomy could be observed as producing a wave line. As compared to nearby years, a peak was noted in 1997 (17 cases), somewhat smaller peak involving six cases was observed in 2002, likewise, 2008 yielded another small peak with five cases. Similar curves were obtained when mosaic and non-mosaic forms were studied separately. Based on the above, we looked for a mutagenic effect that could have been present in an explicit form around about the year 1997 and be associated with the higher incidence of X-monosomy in that period. An increase in the intensity of cosmic radiation could be one of those effects. The extremely high rate of chromosomal aberrations in 1997 coincided with the local minimum of the solar flares, therefore solar radiation could not be blamed for those aberrations. At the same time, however is suggestive of a causal relationship between the increase in galactic cosmic background radiation flux and higher incidence of X-monosomy around about 1997. Conclusions: Examining the incidence of sex chromosome aberrations, with special regard to X-monosomy, we have concluded the latter occurred more frequently during higher cosmic background radiation.
ON VARIATIONS OF HUMAN HEMODYNAMIC PARAMETERS CAUSED BY NEGATIVE PRESSURE BREATHING DURING 15-HOUR HEAD-DOWN TILT
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Semenov Yu.S. , Gorbunova А.А. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Dyachenko A.I. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: December 2021

The cardiovascular reaction to negative pressure breathing (NPB) was studied in human subjects in the condition of 15-hour head-down tilt (-15°). Amplitude and time characteristics of tidal oscillations of physiological parameters synchronous to free and NPB breathing were measured after 14 hours in HDT. Oscillations of cardiovascular parameters were determined using the coherent averaging technique. A multiple increase in amplitude was stated during transition from free breathing to NPB, whereas variations of the other characteristics of oscillations were little affected.
EFFECTOFTAIL-SUSPENSIONONLEVELSOFPRO- ANDANTI-INFLAMMATORY CYTOKINS AND MORPHOLOGICAL CHANGES IN RAT'S PULMONARY TISSUES
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Barantseva M.Yu. , Ozerov D.S. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Dadasheva O.A. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: December 2021

Cytokin regulation of local immune reactions in pulmonary tissues (IL-10, IL-4, TGFb1, TNFα), and morphology of the vascular bed and alveolar epithelium of the lung air compartments were studied in a 15-day tail-suspended Wistar male rats with a body mass of 180–200 grams. Cytokin regulation of the local immunity after suspension was characterized by activation of cell proliferation and differentiation regulator TGFβ1 aimed to forestall the inflammatory and auto immune processes and to promote remodeling of the lung epithelial structure and extracellular matrix.
TECHNOLOGY OF MINERAL NUTRITION AND ILLUMINATION OF CROPS IN A SPACE VEGETABLE GREENHOUSE
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Berkovich Yu.A. , Smolianina S.O. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Smolianin V.G. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Morozov Ya.V. ,   Russian State Agrarian University – Moscow Timiryazev Agricultural Academy, Tarakanov I.G. ,   Russian State Agrarian University – Moscow Timiryazev Agricultural Academy
Published: December 2021

Dependence of Chinese cabbage productivity and nitrate content in eatable biomass on the ammonium and nitrate nitrogen ratio and red light fraction was studied in the context of space greenhouse Vitacycle-T design. Crops were illuminated by a lighting unit assembled of red and white light-emitting diodes (LEDs) producing the photosynthetic photon flux (PPF) of 400–430 µmol/(m2•с) with the ratio of red and white LEDs inputs between 0 and 1.5. The ammonium-nitrate nitrogen ratio in nutrient solutions with stabilized total nitrogen varied from 0 to 1. Under all tested light spectra the favorable range of ammonium nitrogen makes up 15 to 45 mg/L with the maximum of 25 ± 2 mg/L and total nitrogen at 120 mg/L. Ammonium nitrogen increase above 53–55 mg/L leads to crop inhibition. Concentration of nitrates in eatable biomass did not exceed the permissible levels established for leave vegetables irrespectively of the ammonium-nitrate nitrogen ratio and decreased monotonously as ammonium nitrogen was rising above 10 mg/L. According to calculation, the Vitacycle-T root-feeding design (cartages of granular mineral-rich ionite BIONA-312 and slow-release fertilizer Osmocote 14-14-14) is capable to control total nitrogen and ammonium-nitrate nitrogen ratio within the favorable range.
Economic relations in the terminological system
Authors: Rizakulovich Irmatov Ikhtiyor
Published: December 2021

The purpose of the study is to study the peculiarities of terminology based on the analysis of economic relations in the dictionaries of Uzbek linguistics. In order to achieve the purpose of the research, the following tasks are identified: analysis of the literature on the relationship between terms and equonyms, a critical approach to existing theories; highlighting the relationship between terms and equonyms; coverage of equonyms and equonymic relations in Uzbek linguistic terminology. The following methods of scientific analysis were used in the research: linguistic description, system, statistical, contextual analysis methods. The method of linguistic analysis was used in the analysis of the scientific literature on the research topic. The system analysis method was used to illuminate the relationship. Statistical analysis has been widely used in the study of the place of linguistic terms in the Uzbek dictionaries. The results of the research allowed to develop the following scientific and practical conclusions and recommendations: analysis of terms and equonymic relations, helps to organize the terms and interpret the meanings and include them in the general dictionary. In particular, in Uzbek linguistics, issues such as the relationship between equonyms and terms, the peculiarities of linguistic terms are relevant.
Dialectical of Islam and Javanese culture in Suluk Saloka Jiwa by Ranggawarsita
Authors: Zaelani Mohamad , Zuriyati Zuriyati , Rohman Saifur
Published: December 2021

Efforts to find the intersection of Islam and Javanese culture have occurred since a long time ago. One of the efforts was Javanese literary texts that dialects within those two entities. Ranggawarsita figure is an intensely Javanese poet voicing the problem. Through his work, Suluk Saloka Jiwa, written in the XIX Century, Ranggawarsita tells Sang Hyang (God) Vishnu from Java who studied to Sheikh Usman Najid from Turkey. As a result, a dialectic that Sang Hyang Vishnu, in wadag (physical) remains Javanese but spiritually has become an Islamic or monotheist. This article is a philological research of the text of Suluk Saloka Jiwa by Ranggawarsita. With the hermeneutic approach, the author tries to uncover the meaning of the texts (mythical poetry form in Javanese literature). And the spirit of the text can be a model of a cultural strategy seeking the intersection of Islam and Java.
Life Writing through Texts and Images – Picture books by Celebrities
Authors: Hoffmann Lena
Published: December 2021

In the last 15 to 20 years a lot of celebrities have published novels and or picture books for children and adolescents. This article will contextualise this international phenomenon within a theoretical framework of celebrity studies and research on life writing and intermediality. As will be shown, these literary texts for young people by celebrities represent an intermedial life writing that combines texts, illustrations, photographs and forms of online and offline self-curating as well. It is especially the picture book that seems to carry an archival function with respect to the authors’ lives. Here, the celebrities tell about themselves in words and images, they stage themselves as private and authentic persons. Understanding children’s and adolescents’ literature as part of intergenerational communication, these literary texts show different kinds of strategies to prolong the knowledge of a public person in societies’ collective memories.
Writing when Young: Bart Moeyaert as a Young Adult Author
Authors: Joosen Vanessa
Published: December 2021

Duet met valse noten (1983) started as a diary when Bart Moeyaert was twelve years old. After it was disclosed by an older brother, Moeyaert rewrote it during his teenage years as a novel about first love. This article studies the genesis and early reception of Moeyaert’s novel to reflect on young authors who fictionalize real-life experiences and desires. On the one hand, they are credited for being experts on youth and said to have a particular appeal to young audiences for that reason. On the other hand, when texts by young authors are published, they are often edited and mediated by adult professionals. For some scholars, such adult intervention compromises the authenticity of the young author’s voice, while others argue that having your work revised is an inherent part of being published. The genesis of Duet met valse noten displays a complex interaction involving several actors, including young voices. The deletion of controversial passages (a toilet scene, the longing for cigarettes and sexual scenes) illustrates this complexity: the decision to adapt them was only in part governed by adults, and while the young Moeyaert was dissatisfied with some revisions, they also contributed to his aesthetics as a poetic rather than explicit writer.
Factores técnicos del manejo de la calidad agua y sedimento en policultivo camarón-tilapia en estanques
Authors: Juárez-Rosales Jorge J , Ponce-Palafox Jesus , Román-Gutiérrez Alma D. , Otazo-Sánchez Elena M. , Pulido-Flores Griselda , Marmolejo-Santillán Yolanda , Tapia-Varela Raúl , Benítez-Mandujano Mario A
Published: December 2021

El policultivo de camarón-tilapia es una de las estrategias de mitigación para los impactos sanitarios y los efluentes en las granjas camaroneras. Su finalidad principal es incrementar la producción y controlar la calidad del agua de sus efluentes. En casos de éxito se controlaron algunas enfermedades y mejoró la calidad del suelo en estanques de tierra. En esta revisión, se analizan los beneficios que se obtienen en la calidad del agua, sedimento, medio ambiente, incremento del rendimiento y el mejoramiento de los parámetros zootécnicos de camarones co-cultivados con tilapia. Los policultivos de camarón-tilapia pueden contribuir con un efecto positivo sobre la calidad del agua y sedimentos de los estanques y efluentes de las granjas de cultivo, lo cual depende de las condiciones de densidad y ambiente donde se desarrollan. Sin embargo, se requiere adaptar y demostrar su funcionalidad y rentabilidad comercial a pequeña escala e industrialmente.
Caracterización morfológica de la cabra Motilona de Norte de Santander, Colombia
Authors: Herrera-Cáceres William , Hernández-Corredor Leonardo
Published: December 2021

Objetivo. Describir las características morfológicas de la cabra Motilona de Norte de Santander. Material y métodos. Se utilizó una población de 300 individuos (266 hembras y 34 machos) que fueron seleccionadas de forma aleatoria en 8 granjas diferentes del departamento Norte de Santander. La caracterización morfológica de la cabra Motilona se hizo mediante información de 7 rasgos morfológicos cualitativos y 11 rasgos cuantitativos de los cuales se derivaron 14 índices zoométricos. Resultados. Se encontró que existe dimorfismo sexual en los rasgos cualitativos de tipo de cuernos, posición de las orejas y el número de capas de color. Se encontró también que existe dimorfismo sexual entre rasgos cuantitativos como longitud de la cara, anchura de la cabeza, alzada de la cruz, anchura de la grupa, perímetro de la caña y perímetro del tórax. Conclusiones. Los resultados de este estudio sugieren que la cabra Motilona es una población con rasgos homogéneos y por lo tanto se requiere de futuros estudios para profundizar en el conocimiento de caracterización de otros rasgos morfológicos y además en sus características productivas.
Evaluation of an AIDS Educational Mobile Game (AIDS Fighter · Health Defense) for Young Students to Improve AIDS-Related Knowledge, Stigma, and Attitude Linked to High-Risk Behaviors in China: Randomized Controlled Trial
Authors: Tang Jian , Zheng Yu , Zhang Daiying , Yu Xingli , Ren Jianlan , Li Mei , Luo Yue , Tian Min , Chen Yanhua
Published: December 2021

Background

The AIDS epidemic among young students is serious, and effective preventive interventions are urgently needed. Game-based intervention has become an innovative way to change healthy behaviors, and we have developed an AIDS educational game called AIDS Fighter · Health Defense.

Objective

In this study, we tested the effect of AIDS Fighter · Health Defense on young students in improving AIDS-related knowledge, stigma, and attitude related to high-risk behaviors in Southwest China.

Methods

A randomized controlled trial was conducted from September 14 to 27, 2020. In total, 96 students from 2 classes in a middle school were selected by stratified cluster sampling in Luzhou City, Southwest China. The students were randomly divided into the intervention group (n=50, 52%) and the control group (n=46, 48%). The intervention group played the AIDS educational game AIDS Fighter · Health Defense; the control group learned AIDS-related knowledge through independent learning on the QQ chat group. An AIDS-related knowledge questionnaire, a stigma scale, and an attitude questionnaire on AIDS-related high-risk behaviors were used to measure the effect of the AIDS educational game via face-to-face interviews. The user experience of the game was assessed using the Educational Game User Experience Evaluation Scale. The difference was statistically significant at P≤.05.

Results

After the intervention, the AIDS knowledge awareness rate (X̅ [SD], %) of the intervention and control groups were 70.09 (SD 11.58) and 57.49 (SD 16.58), with t=4.282 and P<.001. The stigma scores of the 2 groups were 2.44 (SD 0.57) and 2.48 (SD 0.47), with t=0.373 and P=0.71. The positive rate (X̅ [SD], %) of attitudes of high-risk AIDS behaviors of the 2 groups were 82.00 (SD 23.44) and 79.62 (SD 17.94), with t=0.555 and P=0.58. The mean percentage of the game evaluation was 54.73% as excellent, 31.45% as good, 13.09% as medium, and 0.73% as poor.

Conclusions

AIDS Fighter · Health Defense could increase AIDS-related knowledge among young students, but the effect of the game in reducing AIDS-related stigma and improving the attitudes of high-risk AIDS behaviors was not seen. Long-term effects and large-scale studies are needed to assess the efficacy of game-based intervention.

Trial Registration

Chinese Clinical Trial Registry ChiCTR2000038230; https://trialsearch.who.int/Trial2.aspx?TrialID=ChiCTR2000038230
Pengaruh Senam Bugar Terhadap Tekanan Darah Lansia dengan Hipertensi : Studi Quasi Eksperimental
Authors: Adiputra I Made Sudarma , Sunariati Ni Luh Gede Ita , Trisnadewi Ni Wayan , Oktaviani Ni Putu Wiwik
Published: December 2021

Latar Belakang: Hipertensi pada lansia merupakan peningkatan tekanan darah yang terjadi pada lanjut usia. Senam bugar merupakan aktivitas fisik dengan gerakan yang ringan dan sangat tepat bila dilakukan pada lansia hipertensi.Tujuan: Mengetahui pengaruh senam bugar lansia terhadap tekanan darah lansia dengan hipertensi.Metode: Jenis penelitian ini adalah Quasi Experiment dengan rancangan Non-Equivalent Control Group Design. Jumlah responden yang berpartisipasi sebanyak 36 orang. Penelitian ini dibagi menjadi dua kelompok yaitu kelompok intervensi dan kelompok kontrol, pemilihan sampel diambil dengan teknik Purposive Sampling. Data dianalisis  menggunakan Wilcoxon dan Mann-Whitney.Hasil: Hasil penelitian ini menunjukkan pada kelompok perlakuan nilai rata-rata tekanan darah sistole saat pre-test 168,1 mmHg dan post-test 153,4 mmHg sedangkan diastole pre-test 95,56 mmHg dan post-test 82,67 mmHg, pada kelompok perlakuan secara statistik mengalami penurunan tekanan darah setelah senam bugar lansia dengan p-value <0.001 uji beda dua kelompok didapatkan hasil p-value <0.001, dari hasil ini terlihat ada perbedaan tekanan darah antara kelompok perlakuan dan kontrol.Kesimpulan: Hal ini menunjukkan ada pengaruh yang signifikan senam bugar lansia terhadap tekanan darah lansia dengan hipertensi. Diharapkan lansia berperan aktif dalam mengikuti kegiatan senam dari posyandu lansia secara rutin untuk membantu menurunkan serta mengontrol tekanan darah tinggi.
Analysis of ceiling type to produce energy efficient residential buildings: case study on housing design of puskim pu-bandung city
Authors: Ayuningtyas Nurina Vidya , Adianti Istiana , Suryabrata Jatmika Adi
Published: December 2021

Many houses that exist on this earth. Therefore, it is necessary to have tactical and intelligent thinking in designing a home. Many things are rarely considered related to the effects of the design of building elements when related to the temperature or the energy produced. Existing background regarding efforts to reach a comfortable temperature can not only be solved in terms of mechanical systems, but the architectural approach can help and provide a comfortable effect for its inhabitants. This research was conducted to determine the level of thermal comfort or temperature in the room of a residential design that would be related to the size of energy consumption by applying several alternative designs or ceiling forms. This type of research is research using simulation methods through a computer model. The results showed the use of ceiling type Vaulted Ceiling was able to increase the Surface Inside Temperature value by 3 ° C when compared to the type of drop ceiling. The Mean Radiant Temperature value when using the ceiling vault type rises 0.6 ° C and on the acquisition of Operative, Temperature rises 0.3 ° C. The use of insulation material on the roof can significantly reduce Mean Radiant Temperature and Operative Temperature at 1.7 ° C at Mean Radiant Temperature and 0.8 ° C at Operative Temperature. Seeing the results of the simulation in this study, the recommended ceiling type is to use the drop ceiling type because it is quite capable of keeping the temperature in the room not too high so that thermal comfort can be achieved. However, if you want to apply a ceiling design with a model or type of drop ceiling, it is better to use additional insulation material so that the heat transmission temperature is not too high in the room.
EDITORIAL
Authors: Siswomihardjo Widowati
Published: December 2021

Sekolah Pascasarjana Universitas Gadjah Mada mempunyai minat serta program studi yang beragam. Dengan dasar keilmuan lintas disiplin, dapat menjadi bukti bahwa Sekolah Pascasarjana mengembangkan diri untuk memenuhi kebutuhan keilmuan agar dapat menyelesaikan permasalahan di dalam kehidupan manusia yang juga sangat beragam. Tidak bisa dipungkiri bahwa kondisi pandemi covid-19 tengah melanda semua negara, tetapi ternyata hal itu tidak menyurutkan perhatian para peneliti untuk mempublikasikan hasil penelitiannya. Hal tersebut dibuktikan antara lain dengan banyaknya makalah yang masuk ke tim redaksi. Secara konsisten dan profesional tim redaksi telah memilih serta melakukan penyuntingan terhadap delapan artikel yang dipublikasi dalam penerbitan ini. Adapun penyuntingan artikel telah melibatkan para reviewer yang sesuai dengan bidangnya. Sudah sepuluh tahun Jurnal Teknosains hadir, tim redaksi terus berupaya untuk melakukan penyempurnaan. Mohon maaf apabila masih terdapat kekurangan dalam penerbitan di edisi Desember 2021, Volume 11, Nomor 1. Terima kasih yang tidak terhingga kepada semua pihak yang telah meluangkan waktu serta tenaga dalam proses penerbitan ini. Selamat membaca, semoga bermanfaat bagi pengembangan ilmu pengetahuan serta wawasan akademik kita semua.
Effects of GST on Automobile Dealers Industry
Authors: Agrawal Namita
Published: December 2021

Abstract: India has applied for GST for their taxation system which has already been applied by more than 160 Nations worldwide. GST has changed India’s perception in front of policy makers of other countries, global investors including big automobile companies. The growth of automobile sector has clear correlation with the policy reforms as it affects domestic demand pattern as well as trade balance. The automobile industry in India is the most booming industry from last many years. India has become the fourth substantial automobile market in 2019 with increasing sales by 8.3% to 3.99 million units. It was the seventh substantial automobile manufacturer in 2018. The government of India has also known the importance of automobile industry. India has imposed a flare of hope by determined growth targets, supported by many of vital undertaking such as Digital India and the make in India campaigns. There are many changes made ensuring simplicity in the GST tax system. The purpose of the study is to understand the impact of these changes by Automobile Manufacturers (OEMs). Keywords: GST, Taxation, Commercial vehicle, automobile manufacturer.
Role of Plasma Membrane Redox Activities in Immune Response Mechanisms
Authors: Masih Neerja
Published: December 2021

Abstract: The plasma membrane redox system (PMRS) is an important component of the cell's ability to defend itself against oxidative stress. Many immune signaling pathways are regulated through redox reactions. Biological systems utilize oxidationreduction reactions to modulate their responses to environmental cues. The role of redox molecules such as NO and ROS as key mediators of immunity has recently gathered a lot of interest and attention. Beyond the chemical interactions of NO and ROS that combine to eradicate pathogens, these redox small molecules are effective immune-modulators that regulate cellular metabolism as well as multiple pro-inflammatory and repair/tissue-restoration pathways. Redox molecules such as peroxide, superoxide, NO, and RNS, once thought to be only toxic, are essential in tissue repair. These species are generated, converted and metabolized during host microbe interaction involving the innate immune system. Cytochrome b558 is the flavin binding component of the NADPH oxidase. NADPH oxidases are key producers of ROS. A variety of RNS and ROS is produced in the acidic mileu of phagosomes, which provide an environment conducive to the redox chemistry, which is the first line in fighting infection. Bacterial cell immune response also involves NO. Thus understanding the plasma membrane redox activities can help unravel the mechanisms of immune response. Keywords: Plasma membrane, Redox activities, oxidative stress, NO, ROS, RNS. Nitrous Oxide, Reactive Oxygen Species, Reactive Nitrogen species.
Demographic, Lifestyle, and Dietary Factors Associated with Red Meat Consumption Among A Cross-Section of New York City Residents
Authors: Brandt Eric , Levin Andrew , Holland Margaret , Ferrucci Leah
Published: December 2021

Introduction: Red meat reduction policies have become the focus of public policy in New York City (NYC). To inform on who might be impacted the most by these policies we sought to identify factors associated with red meat consumption among NYC residents.Methods: We studied non-institutionalized adults in the cross-sectional 2013-2014 NYC Health and Nutrition Examination Survey. The outcome was self-reported weekly red meat consumption. We used multivariable linear regression to assess the association of red meat consumption with age, gender, race/ethnicity, US nativity, education, marital status, percentage of ZIP-code in poverty, physical activity, smoking, alcohol, restaurant meals, and dietary components (dark-green vegetables, other vegetables, fresh fruit, poultry, fish/shellfish, sugar-sweetened soda (SSS), and sugar-sweetened fruit drink (SSFD)).Results: Among 1,495 subjects, higher frequency of red meat consumption was associated (-coefficient; p-value) with younger age (-0.08; p=.03), male gender (0.47; p<.001), and greater weekly consumption of alcohol (0.08; p<.001), poultry (0.16; p<.001), fish/shellfish (0.15; p=.01), SSS (0.14; p<.001), and SSFD (0.06; p=.005). Red meat consumption was also associated with race/ethnicity (p=.002), wherein Asian race/ethnicity had highest consumption and ZIP-code percent in poverty (p=.003) wherein those in ZIP-codes with ≥30% in poverty consumed the least red meat.Conclusion: Demographic, lifestyle, and dietary factors were associated with red meat consumption frequency in NYC. Public health efforts in NYC should consider these associations and differences from associations in national data when designing and evaluating outcomes from programs targeting reducing red meat consumption in NYC.
Old categories and new wine geographies. Discussing the creation of value, tradition and identity
Authors:   Centro de Investigación en Alimentos y Desarrollo, A.C., Salas Quesada María del Carmen , Sandoval Godoy Sergio Alfonso ,   Centro de Investigación en Alimentos y Desarrollo, A.C., Núñez Noriega Guillermo ,   Centro de Investigación en Alimentos y Desarrollo, A.C.
Published: December 2021

Wine production is a cultural, creative, versatile activity, and at the same time, it carries conservative and traditional ideas and classifications that, in some cases, do not fit the dynamism and diversity of the global wine scenery. To achieve a better understanding and with the hope to eventually overcome this complex decalage, this article presents a theoretical discussion of value creation in the context of emerging wine-growing areas. The need to incorporate asocio-anthropological perspective to the study of value is explained, and the limits posed by the reproduction of representation and valorization models based on the classic discourse versions of terroir, tradition, and identity are argued. Given the factthat the worlds of wine (Old/New/Third), are being expanded and transformed, this paper shows that the new wine geographies offer a valuable testing ground for a well-aimed interpretation of the winemaking scenarios of the 21st century.
Difference of Conventional Constructivism and Critical Constructivism Approach in International Relations Theory
Authors: Setiyaningsih Dewi
Published: December 2021

This paper argues that Constructivism as the approach in International Relations are still debated. The debate is on Conventional (modern) and Critical (post-modern) constructivsm. Although both are claimed as critical approach (similar in their epistemological aspect) and emerged in the same context and same culture of school in IR, they are different in adopting the methodological aspect. It may caused by the constructivist itself grow along the growing of critical studies and the legacy of IR’s behavoralism which still remains dominantly. Thus, it makes one constructivist hold on to reflectivism too much and another constructivist engaged to positivism in order to prove that constructivism is scientific enough theoretically. Outlining the historical background both context and academic text, this paper analyze this issue in a path.
PENGEMBANGAN PARIWISATA MARITIM DI WILAYAH PERBATASAN: STUDI SUSTAINABLE TOURISM DI NATUNA DAN BINTAN
Authors: Kartika Frizka Dwi , Akbar Dhani , Tohadi Arifajaryan , Kurniawan Muhammad Ikhsan , Pandjaitan Gaby Glearly , Simbolon Gulmok
Published: December 2021

Pembangunan pariwisata yang diusung UNWTO berfokus kepada pariwisata yang berorientasi keseimbangan ekonomi, sosial dan budaya, serta lingkungan yang mana sejalan dengan Pasal 4 Undang-Undang Nomor 10 Tahun 2009 tentang Kepariwisataan dijelaskan bahwa kepariwisataan bertujuan penting dalam pembangunan ekonomi. Pariwisata bahari di perbatasan di wilayah Kepulauan Riau sangat berpotensi untuk dikembangkan, terutama di Kabupaten Natuna dan Kabupaten Bintan. Pertanyaan penelitian adalah strategi promosi seperti apa yang dilakukan untuk sustainable tourism bertaraf internasional di wilayah perbatasan Provinsi Kepulauan Riau? Peneliti menggunakan penelitian kualitatif dikarenakan dalam isu pariwisata pembangunan berkelanjutan. Tourism promotion melalui branding Wonderful Kepri pada fasilitas umum strategis di Singapura, sales promotion, website providing dan lain-lain telah dilakukan. Hal ini guna mendukung potensi sumber daya perairan di Kepri berdasarkan PP No. 50 tahun 2011, yang diterjemahkan melalui Rencana Induk Pembangunan Kepariwisataan dari Nasional hingga Kabupaten/ Kota. Hal ini adalah amanah UU No.10 tahun 2009.
PERAN NEGARA DALAM MENANGANI ANCAMAN KEAMANAN NON TRADISIONAL DI PERBATASAN: STUDI PELANGGARAN KEIMIGRASIAN DI KOTA BATAM
Authors: Tambun Josua Wiliam , Akbar Dhani , Widyarsa Mohammad Riza
Published: December 2021

            Batam sebagai salah satu wilayah di Indonesia yang berbatasan langsung dengan dengan negara luar. Batam bukan hanya sebagai wilayah yang berbatasan langsung dengan Singapura dan Malaysia, namun Batam sendiri juga adalah daerah yang menetapkan sistem Kawasan Bebas (Free Trade Zone). Kawasan bebas itu merupakan sebuah sistem kebijakan otorita suatu daerah untuk mempermudah jalur perdagangan di kawasan perdagangan dan pelabuhan yang berada di Indonesia yang didalamnya berisi terjadinya proses penggudangan barang, kegiatan manufaktur serta kegiatan reekspor tanpa hambatan oleh otoritas kepabeanan/perpajakan. TOCs adalah kejahatan lintas Negara yang dilakukan secara terstruktur. Pada penelitian ini bersifat kualitatif. Penelitain kualitatif sendiri merupakan penelitian yang memberikan penekanan pada pendalaman pemahaman sebuah permasalahan. Dengan diciptakannya produk Mikroregionalisme dan Mikroregionalisasi, yang mana suatu produk negara yang dibarengi dengan aktor non negara pasti ada faktor-faktor yang mendukung untuk terjadinya ketimpangan.
Ar tamborējumu rotātās liturģiskās tekstilijas (19. gs. beigas – 20. gs.) Latgalē
Authors:   Latvijas  Universitātes  Latvijas  vēstures  institūts, Jansone Aija
Published: December 2021

Raksts ir par Latgales liturģisko tekstiliju vēsturi. Lielā apjoma dēļ rakstā analizēta tikai viena no 19. gs. beigās – 20. gadsimtā tautā daudz strādātām, bet maz pētī-tām rokdarbu tehnikām, t. i., tamborējums. Materiāla analīze balstās uz 260 Latgales kultūrvēsturiskajā apgabalā apzinātām ar tamborējumu rotātām liturģiskajām tekstilijām, kas ļauj tuvāk ieskatīties katoļu priesteru balto apģērbu (alba, komža) un balto altārsegu izpildījumā, ieskicēt vietējo rokdarbnieču iesaisti un lomu to darināšanā un rotāšanā, kā arī liturģiskajās tekstilijās lietoto tamborēšanas prasmju pārnesi uz laicīgām, tautā lietotām telpu, gultas un apģērba tekstilijām. Pētījumā izmantota materiāla klasifikācijas, kultūrvēsturiskā un statistikas metode.
Tinjauan Hukum Pasal 302 UU MD3 Mengenai Rangkap Jabatan dan Penggunaan Anggaran Kelembagaan Oleh Anggota DPD RI yang Berstatus Ketua PKK dan DEKRANASDA di Daerah
Authors: Richset Riwukore Jefirstson , Susanto Yohanes , Habaora Fellyanus
Published: December 2021

The purpose of this research is to examine the dual position and budget used of the Regional Representative Council of Indonesia toward the status of position as Chairperson of the Family Welfare Movement and the Chairperson of the National Craft Council in an area based on the provisions of the law. This study was carried out in Kota Kupang for 6 (six) months, from January to July 2019. This study was included in the case study classification. The subjects used were legal references and expert opinions. The type of data used is secondary data with documentation techniques. Analysis of the data obtained was done descriptively. The result of the analysis about concurrent of positions and budget used for DPD RI members in accordance with Article 302 paragraph (1) and paragraph (2) in Law in MD3 are not valid if someone other than being a DPD RI member is also as Chairperson of the Family Welfare Movement, and Chairperson of the National Craft Council.
Problematika Proses Pengadaan Tanah
Authors: Utomo Setiyo
Published: December 2021

The land has a social function; therefore, everyone has the right to make the best use of the land, from the land for agriculture to land to develop an area. This paper aims to analyze land acquisition problems in the West Kutai Regency and forms of legal protection for the community against land acquisition. This research method is normative juridical research. The land is fundamental to support the sustainable development of an area to impact the community whose land is designated for development. The legal umbrella still constrains land acquisition in West Kutai Regency in the form of regional regulations that provide access to the land acquisition process in the West Kutai Regency. The absence of legality of land certificates becomes an obstacle for the government to carry out land acquisition to trigger agrarian conflicts. For this reason, land acquisition, of course, the community must have a sense of sincerity if the land has been included in development activities. However, the government must provide compensation for communities affected by regional development. The concept of land acquisition carried out in an area must have a regional regulation formation in advance. In the land acquisition process, the community knows the legal basis, and the government has a legal basis in land acquisition. Justice for communities affected by land acquisition's impact, the government, must have an ideal system to provide justice for the community in terms of land acquisition.
Peranan Kepala Desa Dalam Pelaksanaan Pembangunan Ditinjau Dari Fiqh Siyasah dan UU Desa No. 6 Tahun 2014
Authors: Rahmatillah Mirza , Nurdin Ridwan
Published: December 2021

The success of developing a village cannot be separated from the role of the Village Head and the entire community. A developed village can be seen from the adequate facilities and infrastructure. The head of government has a big responsibility for the progress of his village in order to create a prosperous society. The formulation of the problem in this study is how the role of the village head in the implementation of development in Li-Eue Village and how the Siyasah Fiqh and Village Law review the role of the village head in the implementation of development in Li-Eue Village. This type of research is classified as field research (field research), which is descriptive analysis, namely research that tells and describes data sourced from primary data through interviews, observations and reports in the form of documents and secondary data by conducting library research in the form of Al- Qur'an, Hadiths, opinions of scholars, laws and regulations, documents and books and other scientific works. Based on the results of the analysis, it can be concluded that the role of the Li-Eue Village head in the implementation of development in Li-Eue Village is generally less than optimal so that it is less trustworthy or responsible for the duties as village head. Judging from the existence of several developments that have not been implemented. And less transparent and less mobilizing community participation. Review of Siyasah Fiqh and Village Law, namely leaders who are less trustworthy and less responsible.
Kedudukan Peradilan Administrasi Negara Sebagai Upaya Dalam Mendorong Terbentuknya Pemerintahan Yang Baik
Authors: Dahlan Khalid , Chandra Anna Erliyana
Published: December 2021

Efforts to encourage the implementation of proper governments are continually done in each country, including one of them in the Republic of Indonesia. A decent government can be realized if it is followed by government decisions that are responsive to the needs and interests of the community. The decision of the state administration officials in the effort to realize a proper government must be based on the general principles of good governance, especially those that have been mentioned in Act. No. 30 of 2014 concerning Government Administration. In term of realizing a proper government, it not only becomes the duty of the state administration officials through the decisions formed, but also the involvement of the community as the plaintiff for any government decision that feels disadvantaged and the state administrative court as an institution that examines and decides disputes between the community and the government by continuing to refer the laws and general principles of a good government is part of realizing a good governance.
Tindak Pidana Pencurian Jaringan Wifi Menurut Pasal 30 Undang-Undang Nomor 19 Tahun 2016 Tentang Informasi dan Transaksi Elektronik
Authors: Syuib M. , Maisarah Maisarah
Published: December 2021

This research is motivated by the number of internet (Wi-Fi) stealing around Syiah Kuala Sub District, Banda Aceh, in which this action can disserve the owner of the internet and against to the law. The method of this research is qualitative in which it describes the result of research objectively to conditions encountered in the gorund. The research problems are how the Wi-Fi internet is theft (modus operandi) and what are juridical consequences of the act according to Article 30 of Law No. 19/2016 concerning Electronic Information and Transactions, and how is the Islamic law perspective on the act of internet stealing. The result showed that the modus operandi of Wi-Fi internet stealing is by using a laptop or mobile phone and downloading certain software or applications they need to break through the security system and obtain a username and password. Theft or internet (Wi-Fi) stealing in Syiah Kuala District, Banda Aceh City, can be punished under Article 30 paragraph (1), (2) and (3) in conjunction with Article 46 paragraph (1), (2) and (3) Law No. 19/2016 concerning Electronic Information and Transactions. The action categorized as illegal access. The theft of the Wi-Fi internet in Islamic law perspective is clearly prohibited (haram) due to someone has used other people property without permission. So, it is expected that the perpetrators or other people in order not to do the actin because it is against to the law, and also expected the Wi-Fi owner could report the case to the police.
Legal Flaws in the Election of Wali Nanggroe 2018-2023 Period in Aceh
Authors: Ihsan Muhammad
Published: December 2021

The problem of elections in public office is often interesting to study, especially with the development of the electoral system which is continually being renewed to prevent corruption, collusion and nepotism, as well as to get candidates who are capable in their fields. One of these public offices which is Aceh-specific is Wali Nanggroe. This institution is a mandate of Aceh Government Law Number 11 of 2006. The determination of the Wali Nanggroe for the 2018-2023 period raises legal problems. Therefore this study will examine the wali nanggroe candidate selection system, the mechanism for selecting wali nanggroe based on Qanun number 8 of 2012, and whether there is a legal flaw in the election of wali nanggroe for the 2018-2023 period. This study uses a normative legal research method with a Law and Conceptual approach. The results of the research show that the wali nanggroe candidate selection system has not been carried out openly and transparently, even though Qanun allows for other candidates, in terms of election mechanisms, according to Qanun, an Election Commission must be formed in which there are 4 elements, but in practice the Commission Elections were not formed, this would be legally problematic, even legally flawed because one of the elements of the Election Commission was not involved as a member of the Election Commission as regulated by the Qanun. The elements that were not involved were representatives of ulama in each district/city.