bluuebunny/crossref_metadata_2025 huggingface dataset:
SIMULATION OF EVOLUTION OF THE LEGUME-RHIZOBIA SYMBIOSIS FOR AN IMPROVED FUNCTIONAL INTEGRITY OF PARTNERS AND FOR ECOLOGICAL EFFICIENCY OF THEIR INTERACTION
Authors: Vorobyov Nikolay I , Provorov Nikolay A
Published: September 2017

Simulation of evolution in the legume-rhizobial symbiosis allowed us to suggest the mathematical criterion (index) for the functional integrity of symbiosis (FIS). Calculation of FIS index is based on analysis of the covariance matrix of partners’ frequencies influenced by fluctuations of the systemic parameters. The positive correlations of FIS with ecological efficiency of symbiosis (its impact on the seed productivity of plants) and a negative correlation with the partners’ diversity indices were demonstrated. The revealed dependences allow us to explain the increasing of structural-functional integrity in mutualistic symbiosis byoperation of the natural selection in favor of an improved ecological efficiency of partners’ interactions.
THE ROLE OF TRANSCRIPTION FACTORS DFOXO, DSIR2 AND HSP70 IN LIFESPAN ALTERATION OF DROSOPHILA MELANOGASTER IN DIFFERENT LIGHT CONDITIONS
Authors: Moskalev Aleksey A , Malysheva Olga A
Published: September 2017

It was investigated the role of stress-response genes (dFOXO, dSir2, Hsp70) in regulation of life span of Drosophila in response to light regime alteration. It was revealed the FOXO-dependant mechanism of lifespan increasing at darkness conditions. The distance of lifespan of FOXO homozygous mutants at different light conditions were absent 3 times from 4 times. It was shown, that homozygotes with deletion of dSir2 have more significant difference between lifespan at standard light and darkness conditions with comparing to wild type and heterozygous strain. The same tendency was also detected the in the strains with Hsp70 deletions. It was produced the evidences of two mechanisms of light regime influence on lifespan: metabolism intensification at light conditions and neuroendocrine-determinated lifespan increasing at darkness conditions.
Genetics and epigenetics of syntropic diseases
Authors: Gorbunova Viktoriya N
Published: September 2017

The genetic components are involved in aetiology of the common human diseases. For most of them it is significant the phenomenon of syntropies — nonrandom combination of different diseases in the same patients. Three methodic approaches have been successfully used for the identification of genetic factors predisposed to the common human diseases: linkage analysis, candidate gene association studies (GASs) and genome-wide association scans (GWASs). The structural features of the many genes make a small but significant contribution to the overall risk of common diseases. Syntropy of related diseases is determined of having of share in disease pathogenesis the functional polymorphisms of genes controlling the same metabolic pathways. Nonrandom combination of different diseases in the same patients is determined of common epigenetic mechanisms involved in expression control of different «gene nets» disorder.
Epigenetical mechanisms of susceptibility to complex human diseases
Authors: Patkin Eugene L , Quinn John
Published: September 2017

Contemporary data concerned an input of epigenetical mechanisms into an etiology and susceptibility to complex human diseases are critically analyzed. The special attention is attended to a specific role of simple tandem DNA repeats, the crucial role of developmental epigenetics in these processes. Patterns of mitotic and intergenerational inheritance of epigenetical modifications are considered.
Noncoding RNA participation in gene expression regulation in yeast Saccharomyces cerevisiae
Authors: Kochenova Olga V
Published: September 2017

Saccharomyces cerevisiae lacks the main components of RNAi-dependent gene silencing. Nevertheless, regulation of gene expression in S. cerevisiae could be accomplished via some other types of noncoding RNA, particularly via antisense RNA. Although, there is a high percent of untranslated RNA in yeast genome only few evidences of noncoding RNA gene regulation exist in yeast S. cerevisiae, some of them are reviewed in the present paper.
Y CHROMOSOME HAPLOGROUP R1a1a7 (М458) OF MODERN BELARUSIANS AND MIGRATIONS OF SLAV’S PREDECESSORS ON BELARUS TERRITORY
Authors: Kushnerevich Elena I , Sivitskaya Larisa N , Bogacheva Anna V , Kotova Svetlana A , Tsybovsky Iosif S , Davydenko Oleg G
Published: September 2017

Investigation of Y chromosome haplogroup R1a1a7 (М458) in ethnic Belarusians from six historic and ethnographic regions has shown that its frequency makes up 14% out of total Y chromosome gene pool diversity. Bearers of R1a1a7 (М458) are concentrated in Pripiat and Neman river basins which is in south and west of Belarus respectively. Expansion of R1a1a7 (М458) on the territory of present day Belarus was most probable associated with the distribution of agriculture in Eastern Europe. In addition, obtained data point to presence of later migration wave, Polab Slavs, for example, from Elba and Oder interfluves in Neman river basin at the border of I–II Millennia.
APOE gene ε4/ε4 “thrifty” genotype and risk of metabolic disorders in the Uralic peoples
Authors: Kozlov Andrey I , Borinskaya Svetlana A , Sanina Ekaterina D
Published: September 2017

The prevalence of APOE gene ε4/ε4 genotype in the populations with various level of “westernization” is under the consideration. It is proposed that the populations with a high frequency of *ε4 undergoing “modernization transition” are in the most vulnerable state. These are the Eastern Finns and especially indigenous people of the North, who have a higher level of diseases of circulatory system than megacity residents.
GENETIC AND MORPHOTYPIC HETEROGENEITY OF SWIMMING POOL BACTERIAL POPULATIONS
Authors: Magdanova Larisa A , Golyasnaya Nadezhda V
Published: September 2017

The populations of resident bacterial species of the swimming pool community such as Pseudomonas aeruginosa, Bacillus sp., Acinetobacter lwoffii and Pseudomonas alcaligenes were analyzed. All these species showed stable in time heterogeneity by spontaneous mutation frequency and biofilm forming ability. There was notably high occurrence of mutators in all investigated populations. Our results show high level of genetic plasticity and adaptivity under conditions of starvation and exposure to biocides.
EPIGENETIC ASPECTS OF ABNORMALITIES OF HUMAN EMBRYO DEVELOPMENT
Authors: Lebedev Igor N
Published: September 2017

Early stages of human embryo development are characterized by an extremely high incidence of reproductive losses. Genomic mutations are the main contributing factor in this phenomenon. However, a significant part of miscarriages cannot explained by current genetic or cytogenetic concepts. A possible impact of abnormalities of the epigenetic genome organization into etiology of reproductive wastages is discussed in the current review. Characteristics of aberrant epigenetic modifications, ontogenetic and molecular mechanisms of their appearance are given in the light of genomic imprinting.
Methylation anomalies in cancerogenesis: search for new genes, development of methods and DNA-markers for diagnosis
Authors: Zaletaev Dmitry V , Strelnikov Vladimir V , Kekeeva Tatiana V , Zemliakova Valeria V , Kuznetsova Ekaterina B , Mikhaylenko Dmitri S
Published: September 2017

The report considers the epigenetic defects and their diagnostics in tumors. Aberrant methylation of the promoter or regulatory region of a gene results in its functional inactivation, which is phenotypically similar to structural deletion. Cancerogenesis-associated genes are often methylated in tumors. Tumors differ in methylation frequencies, allowing differential diagnostics. Aberrant methylation of tumor suppressor genes occurs in early cancerogenesis, and its detection may be employed in presymptomatic and noninvasive diagnostics of tumors.
Is biological invasion crucible for evolution?
Authors: Orlova Marina I
Published: September 2017

During the invasion process multiply introductions via invasion corridors support contacts of propagules from populations isolated before. The contacts occur outside their native range in conditions of differently disturbed ecosystems. Universal genetic mechanisms form the material that is both diverse and unique for natural selective pressure in these contact zones. Invasions provide prerequisites for co-evolution of species having the same origin (and so far period of preceding co-evolution) and those of different regions. Their further co-evolution can occur in recipient system including as formation of new assemblages.
DEVELOPMENT OF MOLECULAR MARKER FOR ASSESSMENT OF INTRASPECIFIC POLYMORPHISM OF RC GENE CONDITIONING RED PERICARP IN RICE ORYZA SATIVA L.
Authors: Tokmakov Sergey V , Mukhina Zhanna M , Bogomaz Denis I , Matveeva Tatyana V
Published: September 2017

Red rice is the worst field weed in all rice-cultivation areas. Early diagnosis of red rice in primary seed breeding program is an overriding task, which solution directly influences the quality of the rice seeds. Red and red-brown colors of pericarp are determined by two loci at least: Rc and Rd, expressing in conjunction with the Rc gene. In this study we have developed an intragenic codominant molecular marker for the Rc gene and tested it with contrasting as to the seed colour rice varieties examined feature. The efficacy of the marker has been shown for 1142 families of rice, each sample containing 120 plants.
Association study of APOE, LPL and NOS3 polymorphisms with the risk of common cardio pathology in children and pregnant women
Authors: Glotov Andrey S , Vashukova Elena S , Kanaeva Maria D , Dvoeglazova Maria O , Danilova Maria M , Pakin Vladimir S , Marochkina Ekaterina Yu , Bicmullina Dina R , Glebova Maria A , Makhrova Irina A , Obraztsova Galina I , Glotov Oleg S , Zainulina Marina S , Ivashchenko Tatyana E , Baranov Vladislav S
Published: September 2017

Polymorphisms of APOE (E2/E3/E4), LPL (1595CG) and NOS3 (-786TC) in groups of pregnant women with and without preeclampsia, in donors, in children with hypertension, children with obesity and metabolic syndrome, and in control children were studied by PCR /RF LP analysis. Statistically significant increase of T/C genotype frequency of NOS3 in pregnant women with preeclampsia as well as in women with physiological pregnancy compared to this one in nonpregnant women of donors group was assessed (56%, 59% and 37%, respectively, F0.03).
Analysis of UCPs, PPARs and PGC-1 gene polyorphism in elderly people from North-West region of Russia
Authors: Tarkovskaia Irina V , Glotov Oleg S , Ivashchenko Tatyana E , Baranov Vladislav S
Published: September 2017

Polymorphism of PPARA G/C, PPARD +294Т/С, PPARG Pro12Ala, PGC-1 Gly482Ser, UCP2 Ala55Val and UCP3 C-55T genes in elderly people (group1) and control group (25-55 aged people) (group2) from North-West Region of Russia was studied by RLFP methods. Higher frequencies of T/C PPARD, Ser/Ser PGC-1 and C/C UCP3 genotypes in group1 compared to group2 were found. Furthermore, it was shown different distribution of PPARA, PPARD, PGC-1 and UCP2 genotypes in man and woman. We suggest that PPARA, PPARD, PGC-1 and UCP3 polymorphism is significant for survival.
The ITS1-5.8S rRNA gene -ITS2 sequence variability during the divergence of sweet-grass species (gen us Glyceria R. Br.)
Authors: Rodionov Alexander V , Kotsinyan Armen R , Gnutikov Alexander A , Dobroradova Marina A , Machs Eduard M
Published: September 2017

Comparative analysis of the sequence ITS1-5.8S rRNA gene-ITS2 of the nuclear genome of 13 species of genus Glyceria, 4 species of Melica and a species of monotypic genus Pleuropogon showed that the species of the genus Glyceria have 3 haplotypes: 1) Haplotype A was found only in species of the subgenus Glyceria section Glyceria (G. septentrionalis, G. fluitans, G. declinata, G. occidentalis, G. notata, G. borealis, G. leptostachya) and in Pleuropogon sabinii; 2) Haplotype C is characteristic of the subgenus Hydropoa, section Hydropoa (G. grandis, G. х amurensis, G. triflora, G. maxima) and sect. Lithuanicae (G. leptolepis); 3) Haplotype B is found in the species of the subgenus Hydropoa sections Striatae (G. elata, G. striata, G. neogaea, G. canadensis), Scolochloiformes (G. alnasteretum, G. spiculosa) and G. lithuanica of sect. Lithuanicae. Species carring haplotype B are located at the base of the phylogenetic tree of the genus Glyceria and/or clustered with low bootstrap indices. On the phylogenetic trees inferred by the analysis of the sequences ITS and 5.8S rDNA both sect. Glyceria and sect. Hydropoa represented two sister monophyly branches. The species Pleuropogon sabinii belong to the branch of subgenus Glyceria as a sister monotypic branch to the branch of the sect. Glyceria.
A study on the prevalence of chronic obstructive pulmonary disease among adults in Madurai, Tamil Nadu
Authors: Saleem Mohamed , Priya Sivasubramanian , Pradeep Manimaran , Sabeetha Kalifulla
Published: September 2017

Background: Chronic obstructive pulmonary disease (COPD) is a major public health problem with increasing prevalence especially in developing countries. Burden of disease estimation is important for decision making, planning, prioritising and allocating funds. It has been found that the recent data on prevalence of COPD is less in south India, especially Tamil Nadu. Hence this study was undertaken in order to estimate the prevalence of COPD in Madurai among adults and its association with socio demographic variables. Methods: This is a community based cross-sectional study done in Kallendiri block of Madurai district with adults aged >30 years of both the sexes as study population. Sample size was 480. Using cluster sampling method, study participants were interviewed with semi-structured questionnaire and peak expiratory flow rate was measured using peak flow meter. Results: Prevalence of COPD was 22.1% among the study population. Males (39.2%) had higher prevalence than females (12.2%). COPD prevalence was significantly higher among increasing age, male sex, illiteracy, low BMI, smokers, inadequate ventilation and those using biomass fuels for cooking. Conclusions: This study has established the fact that COPD is highly prevalent among adults in rural area. For practitioners, the results call for a high index of suspicion of COPD among >30 years with substantial exposure to risk factors. For health policy makers, the results of the current study urge for the development of COPD prevention programs failing which the burden of COPD might result in increased mortality, morbidity and economic burden.
Investigation of Hepatitis A outbreak in Palakkad district
Authors: Zachariah Shilu M. , C. Sreedevi , S. Aswathy , Kokkayil Prathyusha , Mathews Anila A.
Published: September 2017

Background: A study was carried out to investigate an outbreak of viral hepatitis reported by district health authorities from a self-administrative unit, Koppam of Palakkad district in Kerala in the month of November 2016. Methods: An epidemiological investigation was carried out to investigate the outbreak, describe epidemiological features and recommend measures for control. An epidemiological case sheet was prepared, case definition formulated and blood samples were collected to confirm the diagnosis of hepatitis. Environmental samples were collected from wells, soil and tested for hepatitis A virus. Results: 15 blood samples taken from cases of jaundice tested positive for hepatitis A, IgM antibody by ELISA test. More than three fourths 39 (79.6%) of the cases gave a history of having attended the same wedding function prior to the occurrence of symptoms. Attack rate (6.14%) was highest among 15-25 year age group. The water analysis from 3 of the wells in the area showed presence of coliform bacteria. Hepatitis A virus IIIA genotype was isolated from the soil sample of the house of the index case. Consumption of welcome drink was found to be associated significantly with cases than controls (OR 2.77; 95% CI: 1.02-7.52, p<0.05). Conclusions: The hepatitis A (type IIIA) outbreak in Koppam was associated with poor sanitation practices among the people. During a socio-cultural-demographic event like marriage this led to an explosive outbreak. Involving community organizations to generate awareness regarding food sanitation, supported by a system of registration of such events, certification of food handlers can help to prevent future outbreaks.
Effect of Unani medicine on irritant contact dermatitis: case study
Authors: Kawoosa Shahnaz Hafeez , Mushtaq Allaqaband Shafia , . Rakhshandah
Published: September 2017

Contact dermatitis is an allergic reaction of skin which occurs in response to a substance that comes in contact with surface of skin. Irritant contact dermatitis is one of the type of contact dermatitis, most frequently caused by occupational exposure either as an industrial contact or household contact. In Unani medicine, contact dermatitis has been described as an eruption on skin surface in which initially there is erythema, burning sensation followed by formation of papules along with itching on the affected site. Here we report a case study of 54 years male, working in sewage treatment plant having being diagnosed of Irritant contact dermatitis on palmer surfaces of both hands. Patient was given Unani treatment both oral as well as local and was asked for follow up every week. After 28 days of treatment patient had significant improvement with mild scales and no erythema. 
Pattern of neck masses in adult patient in southern region KSA
Authors: Hudise Jibril Yahya
Published: September 2017

Background: Many head and neck diseases manifest as neck masses with a wide range of developmental lesions to malignancies. A neck mass can be defined as any abnormal growth or development from the skull base to the level of the clavicle. This retrospective study to assess the distribution of neck masses related to gender, age, pathology, and anatomical location of neck masses in Asir Central Hospital.

Methods: During a 5-year period (2011–2016), the medical records of 158 patients with neck masses were collected from the department of pathology at Asir Central Hospital KSA. The cases were reviewed for data on gender, age, pathology, and the anatomical location. Comparisons between genders, age groups, and tissue origins were performed. We divided the age to 4 categories: from 15 to 30 years, 31 to 45 years, 46 to 60 years, and more than 60 years. All statistical tests were performed with SPSS software. We exclude thyroid, parathyroid and salivary gland masses.  

Results: Over a period of 5 years, a total of 158 patients (90 men and 68 women) had neck masses resected for pathological assessments. The age of presentation was ranging from 15 to 84 years. Among the 158 cases, 40.5% developed in (from 15 years to 30 years old), 24.7% developed in (31 to 45 years), 20.9% developed, in (46 to 60 years), and 13.9% developed in age more than 60 years. The histopathological diagnosis of the neck masses were congenital 10.1%, inflammatory 28.5%, benign tumor 5.7% and malignant tumor 55.7%.

Conclusions: The age and location of neck masses are the most important variables. When a neck mass is seen, neoplasms should be considered in older adults inflammatory and congenital masses in children and young patients. Although the history, medical examination and additional diagnostic methods provide important information, the exact diagnosis may only be obtained by histopathological examination.
Rousseuanian conservatism
Authors: Reis Cláudio Araujo
Published: September 2017

CONSERVADORISMO ROUSSEAUNIANO

Resumo: o texto procura examinar alguns aspectos da filosofia política de Rousseau à luz do conservadorismo, tal como caracterizado a partir da teoria das ideologias de Michael Freeden. Pretende-se explorar uma possibilidade: e se olhássemos o pensamento de Rousseau através do filtro da ideologia conservadora? Não se trata tanto, aqui, de acrescentar mais uma figura àquela já extensa galeria. O objetivo é, antes, ver, se examinamos através desse filtro o pensamento político rousseuaniano.

Palavras-chave: Jean-Jacques Rousseau. Conservadorismo. Ideologias.

Abstract: for Rousseau, in the State of nature, man is governed by two principles, the “amour de soi” and the pitié, that means. even before of the contest of reason and the moral foundations of morality are present. Endowed with a natural sympathy, the man in this non-historic State is not good because it distinguishes right from wrong, but because the maximum that inspires him comes from stems from the natural goodness and leads him to make your as well as the least bad possible.

Keywords: Pitié. State of nature. Perfectibility. Reason. Moral.
Rousseau’s contractualism under Rawl’s perspective on his conferences about the political philosophy’s history
Authors: Da Silva Delmo Mattos
Published: September 2017

O CONTRATUALISMO DE ROUSSEAU SOB A PERSPECTIVA DE RAWLS NAS CONFERÊNCIAS SOBRE A HISTÓRIA DA FILOSOFIA POLÍTICA (1960-1995)

Resumo: a proposta da presente comunicação consiste em explorar os argumentos de Rawls sobre o contratualismo de Rousseau, em especial, o papel representativo da vontade geral e do pacto social no contexto do seu pensamento político. Para tanto, utiliza-se como pano de fundo as discussões proferidas pelo filósofo americano em uma série de cursos ministrados na Universidade de Harvard, entre 1960 a 1995, e reunidos na obra: Lectures on The History of Political Philosophy (Conferências sobre a História da Filosofia Política). Nesse curso, além de uma análise das condições de possibilidade do argumento do contrato no âmbito da modernidade política, Rawls, na parte destinada a Rousseau questiona, redefine e problematiza várias questões apresentadas pelo filósofo genebrino nas suas obras principais de filosofia política. Por uma questão de objetivo, o propósito definido será o de expor a problematização da vontade geral baseado na exposição de Rawls, especialmente aquelas inquietações teóricas sobre a legitimidade, função e promoção da justiça, liberdade e da igualdade em relação à vontade geral.

Palavras-chave: Contratualismo. Vontade geral. Liberdade. Pacto social. Justiça.

Abstract: the purpose of this paper is to explore Rawls's arguments about Rousseau's contractualism, in particular, about the representative role of the general will and the social pact in the context of his political thinking. To do so, use as background as discussions by the American philosopher in a series of courses taught at Harvard University from 1960 to 1995, and gathered in the work: Lectures on The History of Political Philosophy. In this course, in addition to an analysis of the conditions of possibility of the contract argument in the context of political modernity, Rawls in the part destined to Rousseau questions, redefines and problematizes several questions presented by the Genevan philosopher in his main works of political philosophy. For the sake of purpose, the definite purpose will be to expose the problematization of the general will based on Rawls's exposition, especially those theoretical concerns about the legitimacy, function and promotion of justice, freedom, and equality in relation to the general will.

Keywords: Contractualism. General will. Freedom. Social pact. Justice.
Sovereignty and Democracy in Global Times: acutality of the Jean-Jacques Rousseau Political Philosophy and the limits of the social contract
Authors: Baccega Marcus
Published: September 2017

SOBERANIA E DEMOCRACIA EM TEMPOS MUNDIALIZADOS: ATUALIDADE DA FILOSOFIA POLÍTICA DE JEAN-JACQUES ROUSSEAU E OS LIMITES DO CONTRATO SOCIAL

Resumo: este artigo visa a problematizar os (des)caminhos dos conceitos políticos e das práticas sociais e jurídicas em torno da soberania política do Estado Nacional e da democracia nos tempos de mundialização do Capital. Portanto, revisita e percorre uma breve arqueologia conceitual da Soberania, desde Isidoro de Sevilha até a clássica definição de Jean Bodin nos Seis Livros sobre a República (1576). O propósito é problematizar a filosofia política de Rousseau para, então, perceber e discutir seus limites suas virtualidades, bem como a atualidade de sua noção de Contrato Social e o papel da Filosofia Política na Era do Capital Global.

Palavras-chave: Rousseau. Soberania. Mundialização do Capital.

Abstract: this paper casts doubt on the ways and shunts of political concepts and social and legal practices concerning political sovereignty of the Nation State and democracy at the time of Capital’s globalization. It revisits a brief conceptual archeology of Sovereignty, since Isidore of Seville to the classical definition by Jean Bodin in The Six Books on the Republic (1576). The purpose is casting doubt on the political philosophy of Rousseau, in order to discuss its limits and virtualities, and the topicality of his notion of social contract and the role of Political Philosophy at the Age of Global Capital.

Keywords: Rousseau. Sovereignty. Globalization of Capital.
Rousseau and the Philosophy of Landscape
Authors: Dozol Marlene De Souza
Published: September 2017

ROUSSEAU E UMA FILOSOFIA DA PAISAGEM

Resumo: o propósito do presente ensaio é o de contornar uma filosofia da paisagem em Jean-Jacques Rousseau (1712 – 1778) mediante uma descrição poética que funde a natureza e um “eu” que, em toda a sua inteireza, projeta-se sobre a primeira ao mesmo tempo em que é alterado por ela. Tal fusão, para o caso de uma prosa filosófico-literária que esmaece as fronteiras entre o exterior e o interior, sugere uma especulação a respeito do potencial formativo e autoformativo das coisas que habitam a camada mais epidérmica do mundo: até onde elas “formam” o expectador e se deixam “formar” por ele?

Palavras-chave: Rousseau. Filosofia da paisagem. Formação.

Abstract: the purpose of this essay is to go around a Philosophy of Landscape in Jean-Jacques Rousseau (1712 – 1778) through a poetic description that merges nature and a "self" that, in its entireness, projects itself over the former as it is altered by it. Such fusion, in the case of a philosophical-literary prose which fades the frontiers between the exterior and the interior, suggests a speculation regarding the formative and auto-formative potential of things that reside in the world's most epidermal layer: to what extent do they "form" the spectator and to what extent do they allow themselves to be "formed" by them?

Keywords: Rousseau. Philosophy of landscape. Formation.
Julie or the New Heloise and the moral transgressions of Rousseau
Authors: Maruyama Natalia
Published: September 2017

JÚLIA OU NOVA HELOÍSA E AS TRANSGRESSÕES MORAIS DE ROUSSEAU

Resumo: as descrições do lugar de convívio das personagens na Júlia ou Nova Heloísa revelam o aspecto transgressor das reflexões estéticas de Rousseau. Expressões como vida retirada e doméstica, diversão inocente e simples, gosto pela moderação apontam para uma tentativa de caracterização dos costumes, baseados em seus ideais éticos e políticos. Nosso filósofo não está apenas descrevendo um costume contra outro, mas transmitindo verdades inerentes ao humano, fontes de liberdade e felicidade. A temática estética reside num plano mais fundamental, o da relação entre o homem e as coisas.

Palavras-chave: Costumes. Natureza. Romance. Rousseau. Simplicidade.

Abstract: Descriptions of the characters' place of conviviality in Julie ou La Nouvelle Heloise reveal the transgressing aspect of Rousseau's aesthetic reflections. Expressions such as solitary and domestic life, innocent and simple entertainment, and taste for moderation, point to an attempt to characterize customs, based on their ethical and political ideals. Our philosopher is not only describing one custom against another, but transmitting inherent truths to the human, sources of freedom and happiness. The aesthetic theme lies in a more fundamental plane, that of the relationship between man and things.

Keywords: Customs. Nature. Romance. Rousseau. Simplicity.
Émile and Ancient Medicine
Authors: Kawauche Thomaz
Published: September 2017

EMÍLIO E A MEDICINA ANTIGA

Resumo: trata-se, neste artigo, de discutir o uso de esquemas conceituais do Corpus Hippocraticum no Emílio de J.-J. Rousseau. A hipótese de leitura relaciona o princípio de isonomia dos antigos e o conceito de ordem aplicado ao equilíbrio das faculdades e dos órgãos da criança.

Palavras-chave: Medicina. Educação. Ordem. Isonomia. Moral.

Abstract: this article aims at discussing the use of conceptual schemes from Corpus Hippocraticum in J.-J. Rousseau’s Émile. The reading hypothesis establishes the relation between the principle of isonomy and the concept of order applied to the balance of child’s faculties and organs.

Keywords: Medicine. Education. Order. Isonomy. Morals.
Federal University of Mato Grosso: from Regionalization to the Internationalisation
Authors: De Sá Elizabeth Figueiredo , Monteiro Silas Borges
Published: September 2017

UNIVERSIDADE FEDERAL DE MATO GROSSO: DA REGIONALIZAÇÃO À INTERNACIONALIZAÇÃO

Resumo: ansiada pelos mato-grossenses, a Universidade Federal de Mato Grosso foi criada em 1971, após disputas e reivindicações. O presente artigo pretende revisitar a história da Universidade Federal de Mato Grosso no viés da História Cultural, com enfoque na História das Instituições Escolares, com o objetivo de compreender a representação de universidade materializada na sua criação e funcionamento até a atualidade. Para tal, como fonte foram utilizados: a coleção de Leis e Decretos, periódicos, obras memorialístas, relatórios de gestão da UFMT, Mensagens de governadores encontradas no Núcleo de Documentação e Informação da História Regional (NDIHR), na Biblioteca Estevão de Mendonça e na Reitoria da UFMT.

Palavras-chave: Universidade Federal de Mato Grosso. Ensino Superior. Instituição Escolar. Educação Mato Grosso.

Abstract: Yearned by Mato Grosso, the Federal University of Mato Grosso was established in 1971 after disputes and claims. This article aims to revisit the history of Federal University of Mato Grosso in bias of Cultural History, focusing on the History of Educational Institutions, in order to understand the university representation embodied in its creation and operation to the present. For this were used as source Collection of Laws and Decrees, periodicals, memorials works, UFMT management reports, Governor’s messages found on the Núcleo de Documentação e Informação da História Regional (NDIHR) in Estevão de Mendonça Library and Rectory of UFMT.

Keywords: Federal University of Mato Grosso. Higher Education. Educational Institution. Mato Grosso Education.
An Empirical Analysis of Consciousness Quotient and its Impact on Job Performance in an Organisation
Authors: Aggarwal Namita
Published: September 2017

Purpose: This paper has been designed to measure the Consciousness Quotient of an individual by means of a questionnaire. Also a correlation between CQ with job performance in organisation is studied. Result: This study puts lot of light on concept of Consciousness Quotient. The comprehensive data analysis is been done that helps in understanding the impact of CQ on Job Performance of employees in institutes of higher learning. The present model has been established to see how employees feel connected at work. Conclusion: The study provides a positive relation and positive impact of Consciousness Quotient on the Job performance of employees working in organisation. To see the impact of variables various statistical techniques like correlation, regression, t-test, Anova have been applied in the paper.
Expertise Related to Scholarly Publishing, Especially
Authors: Dagiene Eleonora
Published: September 2017

As Director of VGTU Press and President of the Association of Lithuanian Serials, I have gained a considerable expertise related to scholarly publishing, especially familiarity of the challenges faced by small publishers. I have learned from my experience that a person running a small press and turning it successful and contemporary should have knowledge of different areas and the ability to think creatively.
Managing Marketing : An applied approach
Authors: Capon Noel , Shekhar Singh Siddharth
Published: September 2017

This edition of Managing Marketing : An applied approach, provides students and businesses information on how to market effectively .This book takes a hands-on, step-by-step, easy-to-measure results approach to creating a marketing strategies that has been proven to work even at very large companies. Information on how to do marketing is broken into easy-to-understand steps that together form The Big Picture. This textbook not only provides sharp edge insights but also teaches how the reader can use them in practice. The extensive use of online supplements audios, videos adds to another dimension. They provide deeper insights into relevant issues and makes the book more useful for the reader. The chapters are easy to remember so they can be used in real-world situations.
Strategic Management
Authors: Board Editorial
Published: September 2017

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International Conference On Global Business Strategies for Sustainability (November 2-3, 2017)
Authors: Board Editorial
Published: September 2017

Exchange of knowledge, ideas and issues related to Sustainable Strategies in area of Marketing, Finance, Human Resource Management, Operations and cross functional areas for Business Excellence globally in the context of business sustainability, management, technology and learning for individuals, organizations and society in turbulent environments..
О роли бизнес-разведки в процессах формирования стратегии развития хозяйственного общества
Authors: Магомедов Шамиль Магомедович
Published: September 2017

В статье описана роль бизнес-разведки при формировании стратегии развития компании. Также в статье описываются услуги и некоторые инструменты конкурентной разведки. Сделан вывод, что бизнес-разведка может использоваться хозяйственным обществом, с одной стороны, как инструмент защиты от внешних рисков, включая угрозу поглощения, с другой стороны компания может применять данный инструмент в целях недружественного поглощения интересующего объекта. Ввиду распространения в России корпоративных захватов, выдвинута идея, что компании, неудовлетворенные информацией, полученной при помощи бизнес-разведки, могут прибегнуть к бизнес-шпионажу. Указаны причины роста спроса на услуги «корпоративных разведчиков».
Механизм формирования и развития потенциала малого предпринимательства в сфере создания новых рабочих мест на региональном рынке труда
Authors: Цёхла Светлана Юрьевна , Полищук Елена Анатольевна
Published: September 2017

В исследовании дана характеристика малому предпринимательству в качестве самостоятельного сектора экономики Республики Крым. Представлены основные группы особенностей субъектов малого предпринимательства, дающие возможность оценить степень их важности в формировании продуктивной занятости населения в сравнении с крупным и средним предпринимательством. Описаны особенности развития субъектов малого предпринимательства Республики Крым, оценен их вклад в развитие регионального рынка труда. Предложена концептуальная схема совокупного механизма формирования и развития потенциала малого предпринимательства, способствующая созданию новых рабочих мест в приоритетных видах экономической деятельности, и, как следствие, сокращению уровня общей (по методологии МОТ) и регистрируемой безработицы. Реализация предложенного механизма позволит получить положительный эффект, выраженный в создании значительного количества вновь созданных рабочих мест, в том числе для представителей молодежи, что окажет эффективное влияние не только на процессы, происходящие на рынке труда, но и на устойчивое социально-экономическое развитие республики.
Агропромышленные кластеры: проблемы и ограничения развития
Authors: Завьялов Дмитрий Вадимович
Published: September 2017

В статье рассматриваются проблемы развития агропромышленного бизнеса, проводится анализ факторов, препятствующих и ограничивающих инвестиционную привлекательность агропромышленных кластеров.
PRINSIP-PRINSIP GOOD GOVERNANCE PADA PENGELOLAAN ZAKAT DALAM PERSPEKTIF QARDHAWI: Studi pada Baitul Mal Kabupaten Aceh Tengah
Authors: Fitrah Iwan
Published: September 2017

The existence of various problems in the implementation of zakat management in the zakat organizations originated from the problem concerning some things called the principles of good governance. So to overcome the problems is by strengthening those principles. This study aims to describe the principles of good governance in the zakat management of Baitul Mal Central Aceh District on Qardhawi perspective. The analysis method used is descriptive-qualitative, with case study research strategy. Data collected through interviews, observation, and documentation. The results show that the principles of shariah, trust, equity, and participation have been going well, but the shariah principle implementation becomes constrained when facing the mechanism of zakat as Regional Original Revenue. Principles of accountability and transparancy have been implemented, but still do not use a more adequate system. Furthermore, the zakat management is still inefficient because amil funds still exceed the provisions, and also there is no amil standarization regarding the relevant educational background with zakat to support the zakat management professionally.
BATAS BATAS TANGGUNG JAWAB HUKUM PEJABAT PEMBUAT KOMITMEN TERHADAP KERUGIAN NEGARA DALAM PENGADAAN BARANG / JASA OLEH PEMERINTAH PRINSIP ASAS MASLAHAT
Authors: Pradipta Radian Yudha
Published: September 2017

Procurement involves huge State money. PPK is a party who has authority in carrying out the procurement of goods. Should there be any irregularities that cause material losses to the State’s finances to be the responsibility of PPK. Article 11 of Perpres No. 4 of 2015 concerning Procurement of Goods / Services The Government in selecting PPK must meet the requirements of either integrity, managerial or competence. This research is a normative research with literature study. The result of this study is that although the limits of the PPK’s legal liability to State Losses in Procurement of Government Goods / Services are not explicitly regulated in Presidential Decree No.4 of 2015 on Procurement of Government Goods / Services, but from several articles, especially in Article 11 , Article 12, Article 13 and Article 122 regulating PPK in the event of a State Loss in Procurement of Government Goods / Services. In the event that PPK committed unlawful conduct in its exercise of authority, the CO shall assume responsibility in accordance with the legal liability of PPK for the State Loss from the legal aspects of State administration, civil law and criminal law.
DISSENTING OPINION PUTUSAN SENGKETA MEREK PIERRE CARDIN INDONESIA MELAWAN PIERRE CARDIN PERANCIS DALAM KAJIAN HUKUM ISLAM: Studi Putusan Mahkamah Agung Nomor 557 K/Pdt.Sus-HKI/2015
Authors: Mahmudah Masrifatun
Published: September 2017

This article intents to examine the dissenting opinion in the judges consideration on the Supreme Court Decision No. 557 K/Pdt.Sus-HKI/2015. This article is normative research with statute approach dan conceptual approach. The legal material on this research consist of primery legal materials namely Law No. 15 of 2001 on Trademark and Supreme Court Decision No. 557 K/Pdt.Sus-HKI/2015, while the secondary legal materials are books, journals, research related to trademarks. The judge decide to reject the application of Pierre Cardin because the petition of Pierre Cardin has passed a period of five years from the registration of Pierre Cardin Indonesia. However, the conclusion of this study revealed that Pierre Cardin entitled to be protected because it is a well-known mark. Finally, Pierre Cardin Indonesia has violeted the terms of article 4 jo article 6 paragraph (1) letter b of Trademark Law because he has a bad faith and had imitated the well-known mark.
La experiencia escocesa en los referenda de devolución y secesión = The Scottish experience of devolution and secession referenda
Authors: Harvey Malcolm
Published: September 2017

Resumen: Consultar e involucrar a la población se ha vuelto habitual en los últimos años. El Reino Unido, que no cuenta con una constitución codificada, ha utilizado el referéndum para decidir sobre diversas cuestiones constitucionales, siendo la más reciente la consulta sobre la permanencia del Reino Unido en la Unión Europea en junio de 2016. Este artículo explora la experiencia escocesa de referenda, examinando el fallido referéndum de devolución de 1979, su repetición exitosa en 1997, y el referéndum de independencia de 2014, en el que los escoceses, de forma aparentemente decisiva, decidieron quedarse en el Reino Unido. Este artículo argumenta que, aunque en cada ocasión fueron las consideraciones políticas, más que los principios, los que llevaron al uso del referéndum, defensores de la democracia directa y activistas y defensores de casos similares pueden aprender algunas lecciones de todas ellas. Palabras clave: Escocia, Referenda, Devolución, Independencia. Abstract: Consulting and engaging with the public has become vogue in recent years.  The United Kingdom, without a codified constitution, has utilised the referendum to decide upon constitutional issues, with the vote to leave the European Union in June 2016 the most recent of these.  This article explores the Scottish experience of referendums, examining the failed devolution referendum of 1979, the reversal of this decision in 1997, and the independence referendum of 2014, in which Scots, apparently decisively, voted to remain in the UK.  This article argues that, though on each occasion political considerations rather than principle led to the use of referendums, there are lessons to be learned from each, both for proponents of direct democracy and for campaigners and activists in similar cases.Keywords: Scotland, Referendums, Devolution, Independence
Democracia republicana = Republican Democracy
Authors: Uscanga Barradas Abril
Published: September 2017

Resumen: Este trabajo pretende explicar los orígenes e importancia del republicanismo como teoría aplicable a la democracia, así como su posible aplicación como una válvula de escape a la crisis democrática actual, pues últimamente se  presentan numerosas y constantes críticas al sistema democrático imperante en nuestros días, lo que nos hace pensar en la existencia de una serie de deficiencias tanto políticas como sociales que, quizás, podrían ser subsanadas replanteando el modelo o visualizándolo desde otra perspectiva más acorde a los fines y necesidades de la sociedad contemporánea.Palabras clave: Democracia republicana, libertad como no dominación, virtudes cívicas, liberalismo, crisis democrática, Estado. Abstract: This paper aims to explain the origins and importance of republicanism as a theory applicable to democracy, as well as, its application like a scape valve of the democratic crisis that prevails today, currently, there are many criticisms of today's democratic system, which makes us think of the existence of a series of deficiencies both political and social that, maybe could be rethought or visualized from another perspective, more in line with the aims and needs of contemporary society.Keywords: Republican democracy, liberty without domination, civic virtues, liberalism, democratic crisis, State.
Gestão por temas como metódica adequada para implantação da cultura brasileira de precedentes constitucionais
Authors: Silva Christine Oliveira Peter da , Aguiar Lucas Albuquerque
Published: September 2017

Este artigo trata da gestão por temas como uma metodologia que viabiliza a implementação da sistemática da repercussão geral. Esta, por sua vez, é um instituto próprio do Direito Processual Constitucional que pode ser apresentado como elemento precursor de uma cultura brasileira de vinculação a precedentes constitucionais. Trata-se de estudo sob a influência da teoria da dependência da trajetória e seus corolários e objetiva apresentar as razões que justificam a adoção dessa metodologia como ferramenta para dar efetividade à sistemática da repercussão geral dos recursos extraordinários perante o Supremo Tribunal Federal. A dogmática constitucional guiará o texto argumentativo, que também utilizará dados estatísticos, a fim de conduzir à conclusão de que essa sistemática deve vir associada a uma metodologia de gestão dos recursos extraordinários perante a Suprema Corte brasileira, a qual permita que se prestigie o direito material em discussão visando uma cultura brasileira de vinculação obrigatória aos precedentes constitucionais.
Evaluación de ecuaciones alométricas de biomasa epigea en una selva mediana subcaducifolia de Yucatán
Authors: Ramírez Ramírez Gustavo , Dupuy Rada Juan Manuel , Ramírez y Avilés Luis , Solorio Sánchez Francisco Javier
Published: September 2017

Los objetivos del estudio fueron elaborar y cotejar ecuaciones alométricas para estimar la biomasa epigea (BE) en una selva mediana subcaducifolia del ejido San Agustín, Yucatán, México, y compararlas con ecuaciones existentes. Se seleccionaron 47 árboles de 18 especies con diámetros normales entre 2.5 cm y 41.5 cm. Se midió el diámetro de cada árbol y la altura se estimó antes y se midió después de derribarlo. Se obtuvo el peso fresco de cada componente (fuste, ramas, hojas) en el campo y se tomaron muestras para determinar su peso seco en el laboratorio y extrapolar a todo el individuo. Se elaboraron seis ecuaciones alométricas evaluadas a través del criterio de información de Akaike (AIC), el valor de R2 ajustado y validación cruzada. La mejor ecuación tuvo un valor de AIC de 48.36 y un R2ajustado de 0.96. La validación cruzada mostró un valor de R2 ajustado de 0.72 y un coeficiente de concordancia de 0.56. Contrario a lo esperado, esta ecuación es menos precisa que algunas otras utilizadas para las selvas de la Península de Yucatán, incluyendo ecuaciones locales y de otros continentes, con tamaños de muestra muy contrastantes. Sin embargo, la mejor ecuación elaborada en este estudio permite obtener estimaciones de la BE de las selvas medianas subcaducifolias de Yucatán adecuadas, especialmente para los individuos de mayor tamaño, que son los más influyentes.
Сучасний погляд на проблему різниці довжини нижніх кінцівок у дітей та лікування із застосуванням методів керованого росту (літературний огляд)
Authors: Khmyzov S.O. , Rokutov V.S. , Iershov D.V.
Published: September 2017

Різниця довжини нижніх кінцівок (РДНК) є досить поширеною патологією в дітей та дорослих, вона має поліетіологічний характер. За даними різних авторів, РДНК зустрічається в 40–70 % населення в популяції. Клінічне значення РДНК у дітей визначається комплексними біомеханічними та анатомо-фізіологічними порушеннями опорно-рухового апарату. Етіологічний чинник та ступінь вираженості РДНК (незначний, помірний, значний) визначає тактику подальшого лікування. Для лікування РДНК у дітей запропоновано багато різноманітних хірургічних методів. Корекція РДНК проводиться шляхом вкорочення більш довгої кінцівки або подовження сегментів вкороченої кінцівки. Методи корекції РДНК, механізм дії яких базується на керуванні функцією наросткової зони (НЗ) довгих кісток, є перспективними, упродовж останніх 80 років вони були об’єктом пильних досліджень та експериментальних пошуків. Сучасна тенденція лікування ортопедичної патології в дітей орієнтована на використання малоінвазивних методик хірургічного лікування, саме тому концепція керованого росту, що передбачає використання різних методів впливу на функцію НЗ (епіфізеодез, степлювання, PETS-техніка, тимчасове блокування пластинами), набуває широкої популярності. Саме лікування помірної РДНК (3–6 см) у дітей може ефективно проводитися з використанням методів керованого росту. Використання тимчасового двобічного блокування НЗ пластинами з гвинтами є перспективним напрямком, адже дозволяє проводити оборотне гальмування росту здорової (довшої) кінцівки, чим досягається лікувальний ефект, при цьому значно розширюються показання до використання цього методу. У висновках можна зазначити, що оптимізація та вдосконалення методів лікування РДНК у дітей за рахунок використання малоінвазивних методик, що впливають на функцію НЗ, є актуальною та недостатньо вивченою проблемою, яка потребує подальших досліджень.