bluuebunny/crossref_metadata_2025 huggingface dataset:
Student Reasoning Based on Mathematical Ability in Solving HOTS Problems through Differentiated Learning
Authors: Dian Septi Nur Afifah  , Nur Ika Fatmawati
Published: February 2024

The mathematical abilities of students with reasoning are closely interrelated. The HOTS-type problem is an effort to improve reasoning ability. The ability of students to solve HOTS questions is still relatively low. Through a differentiated learning model, it is expected to help students in the learning process that suits their needs. The purpose of this study is to describe the application of differentiated learning models and describe the mathematical reasoning ability of students who have low, medium, and high abilities. This type of research is qualitatively descriptive with instruments in the form of observation sheets, questionnaires, test questions and interviews. Data analysis techniques include data reduction, data presentation, and conclusions. Test the validity of data using triangulation techniques. The results of this study show that differentiated learning can improve students' ability to reason. Four indicators of mathematical reasoning are, students' ability to present mathematical problems in the form of written statements, students' ability to make conjectures, students' ability to manipulate mathematics, and students' ability to draw conclusions from problems. Subjects with a high level of reasoning meet two indicators. Whereas subjects with moderate levels of reasoning met only three indicators and subjects with low levels of reasoning met only two indicators. Mathematics teachers should provide learning that is in accordance with the learning style of students and students should also do HOTS type questions more often.
Multiple positive solutions to the fractional Kirchhoff problem with critical indefinite nonlinearities
Authors: Yang Jie , Chen Haibo , Feng Zhaosheng
Published: February 2024

This article concerns the existence and multiplicity of positive solutions to the fractional Kirchhoff equation with critical indefinite nonlinearities by applying the Nehari manifold approach and fibering maps.
Russian Orthodox Church: Kremlin’s ‘invisible hand’ in war against Ukraine | A Igreja Ortodoxa Russa: a ‘mão invisível’ do Kremlin na Guerra contra a Ucrânia
Authors: Constantino Pedro
Published: February 2024

The article intends to demonstrate that the foreign policy of the Russian Orthodox Church (IOR) affects the implementation of Moscow’s policy in the war against Ukraine. The main goal is to determine how the Kremlin, through various hybrid capabilities and techniques, uses the IOR to implement its foreign policy vectors. The study is based on a historical analysis of the international activities of the IOR, focusing on the activities of the Department of Church External Relations (DREI) of the Patriarchate of Moscow, which was created, in 1946, by Stalin and taken over by Vladimir Putin. In this context, the DREI of the Patriarchate of Moscow was and continues to be “the invisible hand” of the Federal Security Service of the Russian Federation (FSB), which works under religious cover at the world level.
IMU Sensor Based Omnidirectional Robot Localization and Rotary Encoder
Authors: Marwanto Setyo Budi , Puriyanto Riky Dwi
Published: February 2024

Localization is a technique to determine the position of the robot in an environment. Robot positioning is a basic problem when designing a mobile robot. If the robot does not know its position, then the next robot action will be difficult to determine. To be able to determine the position of the omnidirectional robot requires good speed control on the DC motor. In omnidirectional robots, positioning is through the use of a rotary encoder sensor to count the movement of the omni robot at X and Y coordinates and the IMU sensor to maintain the direction of the robot facing. PID control is also applied to control the rotational speed of each DC motor on the robot wheel. Odometry is the method used in this study. The odometry system aims to estimate the position relative to the initial position of the omni robot to estimate the change in position from time to time. The final result of this research is the application of the odometry method based on a rotary encoder and IMU sensor can produce an effective and stable robot motion and can move in all directions (holonomic) by maintaining the robot's facing direction. The results of the test form simple motions such as forward, backward, right side, and left side motion, as well as forming a box trajectory that has a position error that is not large and quite accurate. The average error value at coordinate X is 1.44 cm and at coordinate Y is 1.67 cm.
Analysis of the Influence of Number of Segments on Similarity Level in Wound Image Segmentation Using K-Means Clustering Algorithm
Authors: Furizal Furizal , Mawarni Syifa’ah Setya , Akbar Son Ali , Yudhana Anton , Kusno Murinto
Published: February 2024

This study underscores the importance of wound image segmentation in the medical world to speed up first aid for victims and increase the efficiency of medical personnel in providing appropriate treatment. Although the body has a protective function from external threats, the skin can be easily damaged and cause injuries that require rapid detection and treatment. This study used the K-Means clustering algorithm to segment the external wound image dataset consisting of three types of wounds, namely abrasion, puncture, and laceration. The results showed that K-Means clustering is an effective method for segmenting wound images. The greater the number of segments used, the better the quality of the resulting segmentation. However, it is necessary to take into account the specific characteristics of each type of wound and the number of segments used in order to choose the most suitable segmentation method. Evaluation using various metrics, such as VOI, GCE, MSE, and PSNR, provides an objective assessment of the quality of segmentation. The results showed that abrasion wounds were easier to segment compared to puncture wounds and lacerations. In addition, the size of the image file also affects the speed of program execution, although it is not always absolute depending on the characteristics of the image.
Integration of Renewable Energy Power Plants on a Large Scale and Flexible Demand in Bangladesh's Electric Grid-A Case Study
Authors: Halim Md Abdul , Akter Mst. Sumi , Biswas Shuvankar , Rahman Md. Shahriar
Published: February 2024

The fundamental objective of this article is to put in renewable energy sources strategically within the context of Bangladesh's electric infrastructure. Solar and wind energy are inherently intermittent and variable, depending on weather conditions. Because of this unpredictability, power generation can fluctuate, making it difficult to maintain a consistent and reliable energy supply. The case study focuses on the problems and opportunities given by large-scale renewable energy power plant integration and the construction of a flexible demand system. The study digs into the technical, economic, and environmental elements of this integration, taking into account factors like as grid stability, fluctuation in energy supply, and the possibility for lowering greenhouse gas emissions. The abstract shows the potential benefits of such integration for Bangladesh's energy landscape and provides useful insights into the broader subject of renewable energy integration in poor countries through a thorough examination. This study can help future recommendations by policy-makers, producers, entrepreneurs, and utilities grow to enable for large-scale renewable energy penetration into the primary utility grid of a community by providing an outline of the energy supply difficulties in Bangladesh considering techno-economic advantages.
Technical and Economic Challenges and Future Prospects of a Smart Grid - A Case Study
Authors: Haque Abrarul , Hussain Md. Naeem , Ali Md. Sumon , Khan Md. Yakub Ali , Halim Md Abdul
Published: February 2024

In order to improve grid efficiency, dependability, and sustainability, smart grid technology is being developed and implemented at the vanguard of updating the world's electrical infrastructure. In addition to looking at the potential implications of smart grid technology, this case study analyzes the technical and financial difficulties encountered during the implementation of a smart grid. Technical issues with energy management and system stability arise when intermittent renewable energy sources are integrated into the smart grid. To make smooth transmission, sophisticated algorithms and grid management strategies are needed. Maintaining data security and privacy is crucial since smart grids mostly depend on digital technology and data exchange. It is a constant worry to defend the grid from hackers and illegal access. The installation of sensors, smart meters, and communication equipment might come with a significant initial cost when implementing a smart grid. One of the main economic challenges is financing these developments while maintaining reasonable power bills. It may be difficult to strike a balance between the interests of technology suppliers, customers, and utilities. Real-time monitoring and control are made possible by smart grids, which improve energy distribution and minimize energy waste. In addition to lowering greenhouse gas emissions, this improves overall energy efficiency. Smart grids can enable EV charging infrastructure as electric vehicle (EV) use increases, providing potential for grid optimization and new income streams for utilities. Reliability could be increased and downtime is decreased in a smart grid when defects can be promptly identified and isolated. The implementation of a smart grid is not without its technical and financial difficulties, but the future seems bright. Overcoming these obstacles may result in an electrical grid that is more sustainable, robust, and profitable for customers as well as utilities. Stakeholder cooperation, flexible regulations, and continuous technical development are needed to address these problems. By providing practical applications and real-world insights into the implementation of a smart grid, the case study acts as a link between theoretical concepts. Stakeholders obtain a comprehensive comprehension of the intricacies involved by analyzing technical and economic obstacles. To maximize the potential of smart grid technology, this knowledge is essential for fine-tuning strategies and creating focused solutions.
O QUESTIONAMENTO COMO ESTRATÉGIA PROMOTORA DE CAPACIDADES DE PENSAMENTO CRÍTICO POR MEIO DE UMA OFICINA TEMÁTICA SOBRE COMBUSTÍVEIS
Authors: Bordoni Ananda Jacqueline , Silveira Marcelo Pimentel da
Published: February 2024

This work is an investigation that discusses the potential of questioning as a teaching and learning strategy to promote critical thinking skills. The research examined the potential of a thematic workshop on fuels in developing critical thinking abilities in students. The qualitative participant-type methodology was used to collect empirical data. Thus, the workshop was implemented in eight classes of the third year of high school, with a total of 123 students. The data from the workshop questionnaires, which were answered by the participants, were analyzed using content analysis and in light of Ennis' Taxonomy and theoretical references on critical thinking. The results indicate a significant positive potential regarding expected abilities such as decision-making and reflection. We conclude that the questioning strategy, through a thematic chemistry workshop, can develop critical thinking skills in students.
Submission system for text-mined annotations
Authors:   Europe PMC Team
Published: February 2024

From algorithms to the bench Text-mining holds the promise of helping researchers to overcome information overload. It is a familiar premise: an avalanche of scientific knowledge is being produced and shared. Teaching machines to “read” might soon be the only manageable way to digest large amounts of information into useful facts.
Bringing PubMed Commons to Europe PMC
Authors:   Europe PMC Team
Published: February 2024

Scientific communication does not stop at the moment of publication. Scientific discussions in the form of post-publication peer review can provide valuable insights for published articles, bring up an alternative research perspective, or even present updates for published research.
Harness the power of text-mining for biomedical discovery: introducing Europe PMC Annotations API
Authors:   Europe PMC Team
Published: February 2024

We are excited to announce the launch of Europe PMC Annotations API, which provides programmatic access to annotations text-mined from biomedical abstracts and open access full text articles. The Annotations API is a part of Europe PMC’s programmatic tools suit and is freely available on the Europe PMC website: https://europepmc.org/AnnotationsApi.
LITERATUR REVIEW: PENGARUH ETIKA PROFESI AKUNTAN TERHADAP PROFESIONALISME AKUNTAN
Authors: Asiawati Intan , Yulita Adepa Apri , Nopiana Rahma Beva
Published: February 2024

Tujuan penelitian ini adalah menganalisis prinsip dasar etika profesi akuntansi. Prinsip Dasar Etika menjelaskan lima prinsip dasar etika akuntansi, termasuk kejujuran, objektivitas, kompetensi, pertimbangan profesional, kerahasiaan, dan perilaku profesional. Etika profesi dalam bidang akuntansi merupakan suatu ilmu yang membahas tentang benar dan salahnya tingkah laku manusia sejauh yang dapat dipahami  oleh pikiran manusia, dan berkaitan dengan pekerjaan yang memerlukan pelatihan dan perolehan pengetahuan khusus sebagai seorang akuntan. metode yang digunakan adalah metode literatur. Metode literatur atau studi kepustakaan dilakukan dengan mencari data atau informasi riset melalui membaca jurnal ilmiah, buku-buku referensi dan bahan bahan publikasi yang tersedia di perpustakaan maupun internet. Adapun sifat dari penelitian ini adalah analisis deskriptif, yakni penguraian secara teratur data yang telah diperoleh, kemudian diberikan pemahaman dan penjelasan agar dapat dipahami dengan baik oleh pembaca.
TELAAH MODAL SOSIAL DALAM AL-QURAN : STUDI TAFSIR QS. AL-HUJARAT AYAT 10
Authors: Alim Mu'min Muh Dian Nur , Ahmed Hasob Hamza Abdulrahim , Abubakar Achmad , Basri Halimah , Fazaka Rif’ah Muh. Azka
Published: February 2024

Dari ayat 10 surat Al Hujurat disebutkan bahwa mukmin atau mukmin semuanya bersaudara, yakni bersaudara seiman. Penelitian ini merupakan penelitian kualitatif deskriptif dengan menggunakan metode penelitian kepustakaan. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana QS. Surat Al-Hujarat Ayat 10 dikaji relevansinya dengan modal sosial. Karena kita orang beriman adalah saudara, maka wajib bagi kita untuk saling menjaga tali silaturahmi dan perdamaian antar sesama, serta taat dan tunduk kepada Allah dan melakukan itu semua hanya karena Allah agar kita semua selalu mendapat rahmat-Nya dalam hidup ini. . Hal ini sejalan dengan konsep modal sosial dalam Islam dimana Islam sangat menjunjung tinggi nilai-nilai seperti hubungan antar masyarakat, hubungan timbal balik antar umat beriman dan rasa percaya yang terlihat dari hubungan dengan Allah SWT. Serta hubungan dengan sesama manusia, ketiga konsep tersebut masing-masing terkandung dalam QS. Al-Hujarat Ayat 10. Dan pelaksanaannya sudah ada sejak zaman dahulu hingga masa keemasan Islam hingga sekarang.
Kata Kunci : QS. Al-Hujurat: 10, Modal Sosial, Jaringan, Timbal Balik, Kepercayaan
KINERJA KEUANGAN ANTARA BANK MUAMALAT INDONESIA DAN BANK ISLAM MALAYSIA BERHAD MELALUI PENDEKATAN ISLAMICITY PERFORMANCE INDEX
Authors: Kesuma Indrawati Mara , Suwarno  , Krisda Siagian  , Ronal Aprianto
Published: February 2024

Penelitian ini bertujuan untuk mengetahui apakah PSR, ZPR, EDR dan IIvsNII berpengaruh terhadap kinerja keuangan bank muamalat Indonesia dan bank islam Malaysia berhad. Metode penelitian kuantitatif dengan menggunakan teknik dokomentasi dengan melakukan studi pustaka berupa jurnal dan penelitian terdahulu serta annual report untuk mendapatkan hasil yang maksimal. Populasi dalam penelitian ini yaitu perbankan syariah Indonesia dan perbankan syariah Malaysia tahun 2015-2019 dengan jumlah sampel dua perbankan yaitu bank muamalat indoensia dan bank islam Malaysia berhad. Hasil penelitian ini menunjukan nilai signifikan PSR adalah 0.378, ZPR adalah 0.738, EDR adalah 0.361 dan IIvsNII adalah 0.958 dimana nilai tersebut lebih besar dari α = 0.05. Dari hasil penelitian tersebut dapat ditarik kesimpulan bahwa PSR, ZPR EDR, dan IIvsNII tidak berpengaruh terhadap kinerja keuangan bank muamalat Indonesia dan bank islam Malaysia berhad.
MODEL PENGENDALIAN STRATEGI, INOVASI DAN KEWIRAUSAHAAN DALAM ORGANISASI PERSPEKTIF EKONOMI ISLAM
Authors: Kurniadi Kurniadi , Mu’min Muh. Dian Nur Alim , Silondae Prades Ariato , Sudirman Sudirman , Parmitasari Rika Dwi Ayu
Published: February 2024

Organisasi atau kewirausahaan menempati posisi penting dalam sebuah negara, sebab dapat mendorong perekonomian. Organisai selalu dihadapkan pada kondisi lingkungan yang dapat mempengaruhi pendapatannya. Perubahan lingkungan membuat perusahaan harus menerapkan strategi terhadap target yang ingin dicapai. Di antara langkah yang dapat diambil adalah inovasi, tujuannya agar dapat menyesuaikan dengan perubahan zaman. Selain itu, perusahaan harus melakukan pengendalian terhadap strategi yang telah ditargetkan. Penelitian ini bertujuan untuk mengetahui bagaimana pengendalian dalam sebuah organisasi terutama dalam pandangan ekonomi Islam, bagaimana inovasi dalam sebuah perusahaan serta bagaimana model kewirausahaan dalam pandangan Islam. Penelitian ini adalah jenis penelitian kualitatif deskriptif dengan metode library research. Penelitian ini menunjukkan bahwa segala bentuk usaha dalam organisasi Islam harus dilaksanakan berdasarkan nilai-nilai Islam. Dalam pengendalian organisasi harus dilakukan selaras dengan visi dan misi perusahaan, harus efektif dan efisien, harus disusun dengan baik dan merefleksikan tujuan dari organisasi. Pengendalian dapat dilakkan dengan beberapa tahap, di antaranya menetapkan standar yang ingin dicapai, mengukur apa yang telah dicapai, membandingkan serta mengevaluasi hasil kinerja. Adapun kegagalan perusahaan dalam menerapakan strategi bisa dipengaruhi seperti politik dan teknologi, serta kemampuan pimpinan yang tidak mampu memahami apa yang terbaik dan dibutuhkan perusahaan. Adapun dalam melakukan inovasi, perusahaan harus memperhatikan dengan baik alasan dan tujuan melakukan inovasi. Inovasi dilakukan diantaranya dengan cara mengidentifikasi lingkungan eksternal (peluang dan ancaman) dan internal perusahaan (kekuatan dan kelemahan). Dalam organisasi Islam, segala bentuk kegiatan dilandasai dengan nilai-nilai agama seperti tauhid, siddiq, tabligh, amanah dan fatanah. Setiap Muslim dalam berwirausaha dituntut supaya memiliki sikap inovatif dan cerdas melihat peluang dalam menjalankan bisnis tanpa melanggar prinsip agama Islam.
PENGARUH KOMUNIKASI DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN PADA PT KARYA ANAK TUNGGAL (HAKA DIMSUM SHOP) BSD SERPONG
Authors: Putri Alya Indisya , Azis Abdul
Published: February 2024

Tujuan penelitian ini adalah untuk mengetahui komunikasi dan disiplin kerja terhadap kinerja karyawan pada PT Karya Anak Tunggal (HAKA Dimsum Shop) Baik secara parsial maupun simultan. Jenis penelitian yang digunakan adalah metode kuantitatif yang bersifat deskriptif. Populasi yang diambil dari seluruh karyawan PT Karya Anak Tunggal (HAKA Dimsum Shop) yaitu sebanyak 64 orang. Pengambilan sampel menggunakan sampel jenuh sebanyak 64 responden. Analisis data menggunakan uji instrumen data, uji asumsi klasik, uji regresi linier, uji koefisien korelasi, uji koefisien determinasi dan uji hipotesis. Hasil penelitian komunikasi (X1) dan disiplin kerja (X2) berpengaruh positif dan signifikan terhadap kinerja karyawan (Y) dengan persamaan regresi Y = 1,527 + 0,228 X1 + 0,745 X2. Nilai hasil koefisien determinasi memiliki pengaruh sebesar 64,9% sedangkan sisanya 36,1% dipengaruhi faktor lain. Uji hipotesis diperoleh nilai F hitung > F tabel atau (56,336 > 4,00). Dengan demikian H03 ditolak dan Ha3 diterima artinya terdapat pengaruh yang signifikan secara simultan antara komunikasi dan disiplin kerja terhadap kinerja karyawan pada PT Karya Anak Tunggal (HAKA Dimsum Shop).
Securing Iot Data Transmission: A Comprehensive Approach Integrating Two-Fish Encryption With Wireless Smart Energy Systems And Iot Cloud Services
Authors: N Ashok Kumar , Ramesh Dr. D. , S Dr. Prashant H. , R Dr. Pallavi , G. Veena B.
Published: February 2024

This work addresses the challenges posed by the interconnected nature of the Internet of Things (IoT). This paradigm, facilitating the seamless connectivity of diverse devices, gives rise to issues such as addressability, confidentiality, and data management. The proposed solution advocates for the integration of the robust Twofish encryption algorithm into wireless smart energy systems, creating a holistic approach that capitalizes on the capabilities of IoT cloud services. Twofish, recognized for its strong encryption capabilities, becomes an integral part of the IoT framework to ensure the security of communication and data confidentiality. Through the amalgamation of Twofish encryption with wireless smart energy systems and IoT cloud services, the approach provides a comprehensive solution for the secure transmission and management of data. This integration enhances system scalability, flexibility, and accessibility, thereby safeguarding the confidentiality of information exchanged over the internet. The paper establishes the superiority of Twofish over lightweight cryptography for low-power devices within IoT systems through a thorough analysis of critical factors. These factors encompass the robust security strength of Twofish, its effective encryption capabilities guaranteeing data confidentiality, the algorithm's maturity validated by extensive scrutiny from the cryptographic community, compatibility and interoperability with diverse platforms, resource efficiency in maintaining a balance between security and device capabilities, and the crucial long-term security assurance required for the extended operational lifetimes of IoT devices. The research findings affirm that the incorporation of Twofish into wireless smart energy systems and IoT cloud services offers a secure and efficient solution for safeguarding sensitive information within IoT environments. This consolidated approach contributes significantly to advancing secure communication and data management in the continually evolving landscape of the Internet of Things.
Enhanced Strategic Surveillance And Competitive Intelligence Systems Through Advanced Big Data Capabilities
Authors: YUCRA JAIR EMERSON FERREYROS , CRUZ RICHARD CONDORI , MIRANDA JUAN CARLOS HERRERA , TIPO RUBEN PLÁCIDO LERMA , NORIEGA JUAN BENITES
Published: February 2024

A systematic review was carried out on the production and publication of research papers related to the study of BigData and Surveillance Systems with the effectiveness of Open Government in Ibero-American countries, under the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) approach. The purpose of the analysis proposed in this document was to know the main characteristics of the publications registered in the Scopus and Wos databases during the study and their scope in the study of the proposed variables, achieving the identification of 33 publications in total. Thanks to this first identification, it was possible to refine the results through the keywords entered in the search button of both platforms, which were BIGDATA and SURVEILLANCE SYSTEMS, reaching a total of 14 documents, excluding duplicates and those that did not meet the analysis criteria. The identified scientific publications were analyzed in the hope of knowing the impact of BigData techniques for the processing of large amounts of information on surveillance systems. The analysis allowed us to identify the position of different authors regarding the proposed topic, as well as the relationship between both variables in the execution of different research projects.
Unveiling Democracy
Authors: Vissers Nora
Published: February 2024

On 11 January, Advocate General Richard de la Tour delivered his Opinions in two cases, against the Czech Republic and Poland, which cautiously uncover part of the core of the EU value of democracy. The Commission launched these infringement cases against the two Member States back in November 2012 and April 2013 respectively. Now that the rule of law is a well-established principle of EU law, these cases present themselves as a chance to focus on a less explored value enshrined in Article 2 TEU. They allow the Court to construct a foundation to address prospective questions regarding democratic principles.
A new window for conservation biogeography
Authors: Chen Jun , Wang Haijun , Zhang Liang , Jeppesen Erik , Xie Ping
Published: February 2024

Classic biogeography provides the context for understanding why large-scale patterns of biodiversity occur where they do. However, over the past half century, human activities have greatly changed biogeographic patterns and caused accelerating loss of biodiversity on the earth. In spite of the Launch of Conservation Biogeography a couple of decades ago, there has been no concerted effort to implement conservation practices for regional biodiversity by integrating ecology and evolution over geographical space and time. This paper presents lessons and experiences from biodiversity protection of the Yangtze River, demonstrating an urgent need for biogeography-based solutions that cannot be easily deduced from current conservation biogeography. We aim to open a new window for conservation biogeography by providing a new cross-level paradigm and a new definition, seeking for biogeographic strategies for the long-lasting preservation of regional biodiversity. We believe that this paper makes a concise conceptual advance in conservation biogeography.
CRISPRa engineered Elite macrophages enable adoptive cell therapy for rheumatoid arthritis
Authors: Huang Yuhong , Wang Zhuqian , Zhong Chuanxin , Chen Hongzhen , Chen Xinxin , Cao Chunhao , Qiu Fang , Xie Duoli , Li Jin , Li Jie , Yang Xu , Lu Aiping , Fu Xuekun , Liang Chao
Published: February 2024

Rheumatoid arthritis (RA) is a poly-articular systemic autoimmune disorder characterized by infiltration of immune cells, synovial hyperplasia and joint destruction. Macrophages (MΦs) can polarize into either pro-inflammatory M1 or anti-inflammatory M2 phenotype in response to different environmental signals. In RA, MΦs are prone to polarize into the M1 phenotype. Reprogramming MΦs has shown promise in treating diseases, e.g., the chimeric antigen receptor-MΦ (CAR-M)-based adoptive immunotherapy. Interleukin-10 (IL-10) is one of the pivotal factors for M2 polarization. Clustered regularly interspaced short palindromic repeats-based transcriptional activation (CRISPRa) harnesses the native machinery in cells to enable a quick and efficient increase of endogenous gene expression. Here, we combined a CRISPRa system with adoptive cell therapy to construct engineered lastingly interleukin-ten (IL-10) expressed MΦs (Elite MΦs). The Elite MΦs possessed powerful anti-inflammatory capability and represented a pre-activated state of M2 MΦs in vitro. The Elite MΦs were more susceptible to an M2 inducer while resistant to M1 inducers. The Elite MΦs displayed enhanced chemotactic characteristics, leading to accumulated in vivo distribution at inflamed sites. Systemic administration of the Elite MΦs relieved inflammation, synovial hyperplasia and joint destruction in mouse models of RA. The Elite MΦs constructed by CRISPRa hold promise for addressing the current unmet medical need in RA.
CLINICAL AND TYPICAL IMAGING CHARACTERISTICS OF CRYPTOCOCCAL MENINGITIS IN HIV INFECTED PATIENT: A CASE REPORT
Authors: Tran Le Thang , Le Thi Thanh Thuy , Pham Ngoc Thach
Published: February 2024

Although Cryptococcal infection is worldwide distribution, it is more seen in the immunocompromised patients. Cryptococcus neoformans is the most common central neurvous system fungal pathogen in HIV infected patients. Besides clinical features and laboratory tests, imaging findings play an important role in the evaluation of cryptococcal infection. In this paper we present an immunocompromised HIV infected case of C. neoformans meningitis with clinical features and imaging characteristics by MR image.
EPIDEMIOLOGICAL CHARACTERISTICS OF COVID-19 PATIENTS WHO DIED IN HANOI IN 2021
Authors: Nguyen Cong Huy , Le Vinh Giang , Dinh Van Quy , Pham Thi Kieu Loan , Dinh Viet Anh , Dao Huu Than
Published: February 2024

Objectives: This study aims to describe certain characteristics of COVID-19 patients who died in Hanoi in 2021.Subjects and methods: A cross-sectional descriptive study was conducted using retrospective data collected from a list of cases managed by Hanoi Center for Disease Control. The study’s subjects are individuals who contracted COVID-19 and were documented within the community in Hanoi city fromJanuary 1st to December 31st, 2021 based on the Ministry of Health’s instruction. In total, there were 59,639 confirmed cases of COVID-19, including 409 deaths.Results and conclusions: In 2021, Hanoi recorded a total of 59,639 cases of COVID-19, including 409 deaths; The case fatality rate (CFR) is 0.68%. Among 409 COVID-19 patients who died, 52% of them were female (male/female ratio is 1/1.08); 92% of the deceased COVID-19 patients were aged 60 and above.With the average age at time of death is 79 years old, female’s average age is statistically significantly higher than male’s; 69% of deceased patients were recorded in urban areas. The average time from onset to death was 14.6 days (median 11 days). 77% of the deaths had not received vaccination, and 81% of them had at least one underlying medical condition. Hypertension and diabetes are two most common underlying medical conditions with rates of 54.5% and 29.3%, respectively.
Effects of Government Price Policies on Major Agricultural Commodities in Andhra Pradesh, India
Authors: Ravi Kumar K. Nirmal , Aziz A.A. , Shafiwu Adinan Bahahudeen
Published: February 2024

This study was concerned with analysis of export competitiveness and quantification of impact of price policies in Andhra Pradesh on net social loss in production and consumption, and welfare gain of farmers and consumers and change in Government revenue with respect to major food grains and commercial crops. Policy Analysis Matrix and Partial Equilibrium Model in the Marshallian economic surplus framework are employed in this study. The findings from Policy Analysis Matrix revealed that, on the input side, the farmers are more subsidized for rice and maize, as Nominal Protection coefficient on Tradable Inputs are less than one across all the major importing countries (unlike for chickpea, cotton lint and chilies (dry)). However, from the output side (Nominal Protection coefficient on Tradable output), the farmers producing rice, maize and chilies (dry) are more protective compared to social prices. Considering both input and output policies together, the farmers are simultaneously protective (Effective Protection Coefficient) for rice and maize and hence, the overall transfer from society to farmers is positive (Subsidy Ratio to Producers). The findings from Partial Equilibrium Model showed that total net social loss was found to be positive implying protectionism favoured the farmers across all the selected commodities. Further, the net social loss in production turned out to be positive confirming the main postulate of this study—a price greater than the equilibrium price will reduce the quantity demanded. The protectionist policies further led to a positive effect of trade liberalization on the welfare in the State and an increase in foreign exchange earnings, except for chickpea (in view of its net-importer status). Unlike farmers, consumers in Andhra Pradesh suffered welfare loss due to higher domestic prices over border prices for rice, maize and chilies (dry), However, there is a considerable increase in Government revenue due to pricing policies formulated by the Government of Andhra Pradesh. The welfare gains to farmers are negative for chickpeas and cotton in view of higher domestic prices compared to border prices. So, the key point evident is that due to protectionism, the magnitude of net loss to consumers’ welfare compared to welfare gain of farmers is higher between Rs. 21916 lakh to Rs. 23768 during TE 2020-21 implying welfare transfers from consumers to farmers. Thus, the Government of Andhra Pradesh is spending an enormous amount of money to keep the protection policies going for the benefit of farmers. However, considering the net importer status of chickpeas, the Government should further escalate the subsidy both in production and marketing programs.
Pellegrini Stieda Syndrome after Traffic Accident: A Case Report
Authors: Gökçeoğlu Yaşar Samet , İncesu Ayşe Nur , Anarat Fikret Berkan , Akgül Turgut
Published: February 2024

This article presents a case study involving a 49-year-old female patient who sustained multiple fractures and an MCL injury to the medial aspect of her knee, which appears to be a post-trauma lesion. Corticosteroid injection was administered to the patient, and her progress was monitored through Range of Motion (ROM) and VAS scores for a period of 18 months. The findings of this study are discussed in detail within this article.
Pengaruh Model Pembelajaran Problem Based Learning Terhadap Hasil Belajar Matematika Siswa Kelas IV SDN 40 Sungai Raya
Authors: Angraini Imelda Tri , Nurcahyo Muhammad Aqmal , Harfinda Elliska Murni
Published: February 2024

Rumusan masalah pada penelitian ini yaitu bagaimana Pengaruh Model Pembelajaran Problem Based Learning Terhadap Hasil Belajar Matematika Siswa Kelas IV SDN 40 Sungai Raya. Metode penelitian yang digunakan adalah eksperimen, sedangkan desain penelitian yang digunakan Quasy Experiment Design. Populasi pada penelitian ini yaitu seluruh siswa kelas IV SDN 40 Sungai Raya yaitu kelas IVA berjumlah 21 siswa dan IVB berjumlah 18 Siswa.
Sampel pada penelitian ini adalah siswa kelas IVA (Kelas Eksperimen) dan IVB (Kelas Kontrol) SDN 40 Sungai Raya. Teknik yang digunakan untuk penentuan kelas eksperimen dan kontrol menggunakan sampel jenuh. Pada pengumpulan data peneliti menggunakan soal tes. Teknik pengumpulannya menggunakan tes.
Pengujian hipotesis menggunakan rumus independent sample t-test diawali dengan uji prasyarat, yaitu dengan uji normalitas dan homogenitas. Hasil penelitian ini menunjukkan terdapat pengaruh model pembelajaran problem based learning terhadap hasil belajar matematika siswa kelas IV SDN 40 Sungai Raya. Hal ini ditunjukkan dengan hasil t-test, yaitu thitung (2,739) > ttabel (2,021) dengan taraf singnifikansi sebesar 0,05. Hasil rata-rata perolehan nilai posttest kelas eksperimen sebesar 58,80 lebih baik dari hasil rata-rata posttest kelas kontrol yaitu 45,44 pada KKM yang ditentukan, yaitu 65.
Pengembangan Media Miniatur Sistem Tata Surya 3D terhadap Pengenalan Sistem Tata Surya Kelas VI SD
Authors: Parmadi Tomi , Nurcahyo Muhammad Aqmal , Listiarini Yuni
Published: February 2024

Materi sistem tata surya merupakan materi yang tidak dapat dilihat langsung oleh mata sehingga diperlukan media untuk menjelaskan secara rinci tentang benda-benda langit yang tersusun dalam sistem tata surya. Miniatur sistem tata surya menjadi salah satu alternatif dalam memvisualisasikan suasana luar angkasa di dalam kelas yang tidak bisa dijangkau oleh siswa. Penelitian ini termasuk penelitian pengembangan Research And Development (R&D) dengan model pengembangan ADDIE yang dikembangkan oleh Dick dan Carry terdiri atas lima langkah, diantaranya (1) analisis, (2) perancangan, (3) pengembangan, (4) implementasi, (5) evaluasi. Pengembangan media pembelajaran ini divalidasikan kepada ahli media, ahli materi. Hasil validasi dari semua ahli menunjukkan bahwa pengembangan media pembelajaran miniatur sistem tata surya 3D ini sangat baik/layak untuk digunakan di kelas VI SD/MI. Hal ini dibuktikan dengan validasi dari ahli media dan ahli materi serta respons siswa dan uji coba keefektifan (diukur post-test). Meminimalisasi keterbatasan siswa dalam memahami konsep dasar tata surya pada mata pelajaran IPA yang pada kenyataannya benda-benda langit tidak dapat dilihat secara langsung oleh indra penglihatan manusia. Maka dari pada itu pembelajaran akan lebih menarik jika menghadirkan lingkungan alam atau suasana alam di dalam kelas.
Urgensi Pendidikan Moral Sekolah Dasar dalam Membentuk Karakter Religius di Era Digital menurut Henry Alexis Rudolf Tilaar
Authors: Annur Pingki Alfanda , Susanti Eri , Gera Irega Gelly
Published: February 2024

Pendidikan merupakan proses transformasi perilaku, peningkatan pengetahuan, dan pengalaman hidup untuk membentuk peserta didik menjadi pribadi yang lebih matang dalam berpikir dan berperilaku. Pendidikan moral anak sekolah dasar sebagai fondasi utama menciptakan generasi berdaya saing dan memiliki ketahanan karakter, terutama dalam Konsep religi atau agama membawa aturan dan kewajiban sebagai pedoman hubungan dengan Tuhan, sesama manusia, dan lingkungan. Kondisi ini sejalan dengan pemikiran Prof. Dr. H.A.R. Tilaar, M.Sc. Ed, seorang pendidik Indonesia terkemuka, memiliki pandangan yang kuat terkait pendidikan anak usia sekolah dasar,terutama moral dan pembentukan karakter religi menghadapi problema tantangan teknologi di Indonesia dewasa ini. Penulisan artikel ini bertujuan untuk menjelaskan urgensi pendidikan moral di sekolah dasar sebagai landasan  moral dan spiritual yang kokoh Khususnya dalam menghadapi era digital.
Hakikat Manusia ( Perspektif Filsafat Pendidikan Islam)
Authors: Vina Destiana  , Lntan Putri Lestari  , M Haris Hanafi  , M Sofwan Ghalib  , Wismanto Wismanto
Published: February 2024

This article aims to describe human nature from the perspective of Islamic educational philosophy in order to gain a comprehensive understanding of human nature. The main sources for this type of qualitative research, called library research, are books, journals and other scientific articles. The collected data was analyzed using content analysis to make it easier for the author to filter the main ideas from various existing sources and narrate them as the focus of the research. The results of this article's research: (1) The terms used to refer to humans in the Koran include al-Insan (refers to humans who have special qualities and potential), al-Basyar (refers to humans as living creatures), and al-Insan (calls humans who have privileges and humans who have potential), al-Basyar (calls humans as living creatures). -Nas (calls humans as social creatures): (2) Characters have different views but are essentially the same regarding the nature of humans, namely humans are creations whose potential is different from other creations of God: (3) Humans are called ahsan al-taqwin , which places humans in a strategic position as servants of Allah and Caliph of Allah. Therefore, humans should try to discover their true nature to realize how great a gift God has given in the form of potential so that humans can optimally carry out their functions in worship and serve Allah SWT.
MUKAYESELİ HUKUK BAĞLAMINDA İHALEYE FESAT KARIŞTIRMA SUÇU (TCK Md. 235)
Authors: Yıldız Ramazan
Published: February 2024

Bu araştırmanın amacı ihaleye fesat karıştırma suçunun ceza hukuku bağlamında incelenerek Almanya, Avusturya, İtalya, İspanya, Fransa, Brezilya ve Güney Afrika ülkelerinde nasıl uygulandığının karşılaştırmalı olarak incelenmesidir. Günümüz açısından bakıldığında ihaleye fesat karıştırma suçunun TCK’da “Ekonomi, Sanayi ve Ticarete İlişkin Suçlar” başlığı düzenlendiği ve kamu yararının korunması, serbest rekabetin sağlanmasının ve bu konuda topluma güvence sağlanmasının amaçlandığı anlaşılmaktadır. Karşılaştırmalı hukuk açısından bakıldığında, ihaleye fesat karıştırma suçunun sadece Türkiye’de bu isimle düzenlendiği ve ihale süreciyle ilişkilendirildiği, diğer incelenen ülkelerde ekonomik faaliyetlerde dolandırıcılık, rüşvet ve yolsuzluk gibi hukuka aykırı davranışlar bağlamında ele alındığı tespit edilmiştir. Suçun cezalandırılması açısından bakıldığında gerçek kişilerin 3-5 yıl arasında bir hapis ve çeşitli miktarlarda para cezası, tüzel kişilerin işlemesi durumunda değişen sürelerde ihaleden uzaklaştırma veya yetki feshi, çek kesme, ikamet yasağı, çeşitli haklardan men, mülkün müsaderesi gibi çeşitli tedbirlerin uygulandığı anlaşılmıştır.
خارطةُ طرِيق تعدِيل الدستُور
Authors: أ.د.حسن الياسري
Published: February 2024

إنَّ مما لا شك فيه أنَّ الدساتير تُسن في ظروفٍ زمنيةٍ معينةٍ ، ثم ما تلبث أن تتعدل مع تغيُّر تلك الظروف ، فالدساتير ما وضعت كي تكون خالدةً وصالحةً لكلّ زمانٍ ، بل لتحكم مدةً زمنيةً معينةً لها ظروفها الخاصة ؛   لذلك لا عجب أنْ يتمّ تعديل الدستور العراقي الآن بعد تغيُّر الظروف التي وُضع فيها. إلّا أنَّ هذا التعديل ينبغي أنْ لا يكون مدخلاً للطعن به ، ذلك الطعن الذي أراهُ من قبل بعض الأفراد غير المحيطين بالظروف الملابسة لوضعهِ وصياغتهِ ، من الذين يحكمون على الدستور بعقلية 2020 لا بعقلية وضعه عام 2005 , فكما هو معروفٌ للجميع أنَّ العراق في ذلك الحين كان واقعاً تحت الاحتلال ، والدبابات الأميركية تسير في الشوارع العراقية ، والإرهاب التكفيري يرفع راية إبادة المكون الشيعي ، وجامعة الدول العربية تُجمِّد مقعد العراق فيها ، ومعظم الدول العربية تعادي العراق جهاراً نهاراً، والمفخَّخات تضرب العراقيين يومياً في أسواقهم , ومستشفياتهم, وجامعاتهم, ومساجدهم, وعتباتهم المقدسة ، والإرهاب يستبيحُ دماء أعضاء لجنة كتابة الدستور ويهدَّدهم بالقتل - وفعلاً تمّ اغتيال ثلاثةٍ منهم- ... ، وفوق ذلك الخلافات السياسية الحادة والمعقدة حول شكل الدولة وشكل الحكومة والفيدرالية ... ونحو ذلك من أمورٍ ليست بمخفيةٍ على أيّ عراقيٍ ، ولكنّ يبدو أنَّها مُغيبةٌ عن أولئك الطاعنين ، الذين يحكمون دون نظرٍ لهذه الظروف .
ومن جهةٍ أخرى فإنَّ الدستور مملوءٌ بالإيجابيات وعناصر القوة ، تلك الإيجابيات التي تفتقر إليها معظم دساتير المنطقة العربية ، التي التفت إليها كثيرٌ من المتخصصين الأجانب دون بعض العراقيين .!! نعم الكلّ يُقر بوجود بعض الهفوات ، التي كانت وليدة الصراعات السياسية العاصفة ، وربما الغالبية يطالبون الآن بالتعديل ، إلّا أنَّ ما أودُّ الإشارة إليه في هذا الصدد هو ضرورة أخذ عاملين بعين الاعتبار:
 الأول : إنَّ من الضروري بمكانٍ أخذ الظروف الملابسة لوضع الدستور في الحسبان ، تلك الظروف المذكورة فيما سلف .
الثاني : إنَّ الدستور ينبغي أنْ يُحاكم بعقلية وقت وزمن سنِّه في عام 2005 ، لا بعقلية 2020 أو 2030 مثلاً ؛ وذلك لأنَّـه وُضع ليحكم مدةً زمنيةً معينةً – كما ذُكر آنفاً - ، لا أنْ يكون خالداً ، فهو ليس قرآناً ولا كتاباً سماوياً خالداً , لذلك يتحمل الفرقاء السياسيون مسؤولية عدم تعديله في السنوات المنصرمة ، إذْ كان يتعيّن تعديله قبل عشر سنوات في الأقل ؛ لأنَّـه نجح في إنقاذ البلد في بداية سنِّه ، ونجح في إقامة الحكم الديمقراطي ، وتأسيس الحقوق والحريات بصورةٍ لا نظير لها في كلّ دساتير المنطقة ، وارتقى في بعض مفردات هذه الحقوق والحريات ما موجود في بعض الدساتير المتقدمة ، وليس هذا تنظيراً أو رجماً بالغيب ، وإنّما ناجمٌ من تجربةٍ شخصيةٍ في متابعة دساتير العالم .
وبالمحصِّلة كان يتعيّن تعديل هذا الدستور من سنواتٍ مضت ، أمَا وأنَّــه لم يُعدل فيما مضى ، فإننا نُجدَّد دعوتنا في ضرورة تعديله الآن.
أثر جائحة كورونا على النساء العاملات ودور الارشاد النفسي والمهني في تعزيز التوافق النفسي لديهن دراسة نوعية
Authors: أ.د. صاحب عبد الجنابي  , الباحثة: علا غازي بدر
Published: February 2024

هدفت الدراسة التعرف الى أثر جائحة كورونا على النساء العاملات ودور الارشاد النفسي والمهني في تعزيز التوافق النفسي لديهن. استخدمت الدراسة المنهج الوصفي التحليلي النوعي على عينة بلغت من (30) امرأة عاملة، إضافة الى (10) مرشدين نفسيين، وتم اختيار العينة بطريقة قصدية، لتصل النتائج الى وجود عدد من المعيقات والتحديات الاجتماعية التي تواجه المرأة العاملة حيث تبين ان لجائحة كورونا دورفي التغير الاجتماعي للمجتمع الاردني وما صاحبها من ازدياد للأمراض النفسية كالقلق والرهاب الاجتماعي، و أشارت الدراسة الى أن الرجل خلال فترة كورونا وما قبلها وبعدها لا زال يرفض تشارك الفضاء الخاص مع المرأة، بالإضافة الى المعيقات التي يضعها الزوج أمام زوجته العاملة والتي تبدأ بعدم تفهمه لوضعها خلال أزمة كورونا وما بعدها، ومطالبتها بالعمل في المطبخ من عجين وخبز وإعداد الحلويات على الرغم من عودة المخابز والمطاعم للعمل بعد كورونا، كما أظهرت الدراسة وجود آثار اقتصادية متمثلة بالآثار المادية نتيجة تضرر العديد من وظائف النساء مما يلحق بهم أضرارا مادية ومعنوية تمثلت بخفض الأجور والرواتب او فقدهن لوظائفهن وبالتالي انسحابهن من سوق العمل.
مسؤولية الطبيب عن تجربة العلاج على المرضى
Authors: أ.م.د. زينة قدرة لطيف
Published: February 2024

تعدُّ التجارب الطبية على الانسان لا يمكن الغنى عنها؛ كونها الوسيلة الوحيدة لتقدم العلوم الطبية لكنها توجد بعض المشاكل التي من الممكن أنْ تثيرها التجارب بسبب الاساليب والطرق الفنية المتنوعة في المجال الطبي؛ لذلك خصصنا البحث لتحديد المسؤولية المدنية عن التجارب الطبية.

وعليه، فقد تمَّ التركيز على ماهية التجارب الطبية من حيث التعريف بها والوقوف على الخصائص والضوابط والشروط القانونية لإجرائها، ناهيك عن التّطرق المسؤولية التي تقع على عاتق الطبيب.

وعرضنا في هذا المقام الى عدة تشريعات وبينا موقفها من هذه المسالة، لاسيما التشريع العراقي الذي كان قاصراً في تنظيمها، وعرجنا على الأثر المترتب على قيام هذه المسؤولية والذي يتمثل بالتعويض وتقديره من قبل السلطة المختصة وختمنا هذا البحث بالعديد من الاستنتاجات والمقترحات التي نأمل من المشرع العراقي اخذها بعين الاعتبار.
المزاحمة في الأنظمة السياسية دراسة في الدور الامريكي – الروسي في منطقة بحر قزوين
Authors: م. ايسر علي جواد الياسري  , م.د  سيف حيدر الحسيني
Published: February 2024

إنَّ السبب الرئيسي للمزاحمة والتنافس للأنظمة السياسية ( الولايات المتحدة الامريكية ، روسيا ) في منطقة بحر قزوين هو تعدد مصادر الطاقة الهائلة من النفط ، والغاز الطبيعي ، وهذا ما شكل عامل جذب مؤثر للقوى الدولية ، اذ ترى الولايات المتحدة الأمريكية ، في هيمنتها على مصادر الطاقة العالمية ، عاملا ضروريا لديمومة هيمنتها على العالم ،  وذلك ما جعل روسيا الاتحادية تدرك أن تطوير موارد طاقوية لدول آسيا الوسطى بعيدا عن الدور والمساهمة الروسية سيدفع هذه الدول الى التحرر من القيد الروسي ولن تصبح روسيا الاتحادية الفاعل والمحرك الاول في هذه الجمهوريات، كما أن الشراكات مع شركات النفط الامريكية يمكن أن تؤدي الى زيادة الاتصال مع حكومة واشنطن ومن شان ذلك أن يؤدي الى اضعاف روابطها السياسية والاقتصادية بموسكو وهذا ما تخشاه روسيا الاتحادية ، لذلك ادركت ضرورة مزاحمة الولايات المتحدة في هذه المنطقة للحفاظ على مصالحها .
Review of Urinary Diversion (Mainz II) for Women with Irreparable Vesico-Vaginal Fistula (VVF) In Eritrea, 2022: A Retrospective Study
Authors:   Department of Surgery, Halibet Regional Referral Hospital, Asmara, Eritrea, Mekonen Yohannes
Published: February 2024

Introduction: Mainz II urinary diversion procedures are increasingly being performed in the developing world for irreparable obstetric fistulas. Our goal was to review the long-term complications of continent urinary diversion and to evaluate the feasibility of the recommended follow-up protocols in a country with limited resources. Methods: The medical records of patients who underwent urinary diversion or who are under follow-up for irreparable vesico-vaginal fistula (VVF) at National Fistula center (NFC) in Mendefera, Eritrea, between February 2004 and December 2021, were reviewed. Descriptive statistics was used to depict the complications and surgical outcomes. Results: Urinary diversions were performed in 47 patients. The average duration of stay after surgery was 18 days. Metabolic panel and arterial blood gases (ABG) were found only in 26 of the records which showed hyperchloremic acidosis in 22 (84.7%) and decreased kidney function in 8 (30.7%) of the women. Night time incontinence was found in 24 (51.1%) of the cases with 9 (19.1%) experiencing symptomatic renal infections which required admission. Three of the patients developed pouch stones and two patients developed hydronephrosis. Five patients were able to conceive after diversion. Eleven (23.4 %) of the women were lost to follow-up and 10 (21.3 %) died, with majority (70%) of them with unknown cause of death. Conclusion: On top of the long-term complications following diversion, there was substantial loss to follow-up and death after urinary diversion. Therefore, innovative approaches and continuous financial support to ensure patient return or local follow-up in residential regions need to be developed to overcome barriers to guarantee continuity of care and to decrease the morbidity and mortality of these women.
CONTRIBUIÇÃO AO ESTUDO E EMPREGO DA CONJUNTURA
Authors: Palhano Raimundo Nonato
Published: February 2024

ACERVO HISTORICO
A INDÚSTRIA DE LATICINIOS NO NORDESTE (*)
Authors: ETENE
Published: February 2024

ACERVO HISTORICO