bluuebunny/crossref_metadata_2025 huggingface dataset:
Spinal glial cell line-derived neurotrophic factor infusion reverses reduction of Kv4.1-mediated A-type potassium currents of injured myelinated primary afferent neurons in a neuropathic pain model
Authors: Shinoda Masamichi , Fukuoka Tetsuo , Takeda Mamoru , Iwata Koichi , Noguchi Koichi
Published: March 2019

High frequency spontaneous activity in injured primary afferents has been proposed as a pathological mechanism of neuropathic pain following nerve injury. Although spinal infusion of glial cell line-derived neurotrophic factor reduces the activity of injured myelinated A-fiber neurons after fifth lumbar (L5) spinal nerve ligation in rats, the implicated molecular mechanism remains undetermined. The fast-inactivating transient A-type potassium current (IA) is an important determinant of neuronal excitability, and five voltage-gated potassium channel (Kv) alpha-subunits, Kv1.4, Kv3.4, Kv4.1, Kv4.2, and Kv4.3, display IA in heterologous expression systems. Here, we examined the effect of spinal glial cell line-derived neurotrophic factor infusion on IA and the expression of these five Kv mRNAs in injured A-fiber neurons using the in vitro patch clamp technique and in situ hybridization histochemistry. Glial cell line-derived neurotrophic factor infusion reversed axotomy-induced reduction of the rheobase, elongation of first spike duration, and depolarization of the resting membrane potential. L5 spinal nerve ligation significantly reduced the current density of IA and glial cell line-derived neurotrophic factor treatment reversed the reduction. Among the examined Kv mRNAs, only the change in Kv4.1-expression was parallel with the change in IA after spinal nerve ligation and glial cell line-derived neurotrophic factor treatment. These findings suggest that glial cell line-derived neurotrophic factor should reduce the hyperexcitability of injured A-fiber primary afferents by IA recurrence. Among the five IA-related Kv channels, Kv4.1 should be a key channel, which account for this IA recurrence.
Racial/ethnic disparities in hospital utilization in intracerebral hemorrhage
Authors: Cruz-Flores Salvador , Rodriguez Gustavo J , Chaudhry Mohammad Rauf A , Qureshi Ihtesham A , Qureshi Mohtashim A , Piriyawat Paisith , Vellipuram Anantha R , Khatri Rakesh , Kassar Darine , Maud Alberto
Published: March 2019

Background and purpose

There is evidence that racial and ethnic differences among intracerebral hemorrhage (ICH) patients exist. We sought to establish the occurrence of disparities in hospital utilization in the United States.

Methods

We identified ICH patients from United States Nationwide Inpatient Sample database for years 2006–2014 using codes (DX1 = 431, 432.0) from the International Classification of Diseases, 9th edition. We compared five race/ethnic categories: White, Black, Hispanic, Asian or Pacific Islander, and Others ( Native American and other) with regard to demographics, comorbidities, disease severity, in-hospital complications, in-hospital procedures, length of stay (LOS), total hospital charges, in-hospital mortality, palliative care, (PC) and do not resuscitate (DNR). We categorized procedures as lifesaving (i.e. ventriculostomy, craniotomy, craniectomy, and ventriculoperitoneal (VP) shunt), life sustaining (i.e. mechanical ventilation, tracheostomy, transfusions, and gastrostomy). White race/ethnicity was set as the reference group.

Results

Out of 710,293 hospitalized patients with ICH 470,539 (66.2%), 114,821 (16.2%), 66,451 (9.3%), 30,297 (4.3%) and 28,185 (3.9%) were White, Black, Hispanic, Asian or Pacific Islander, and Others, respectively. Minorities (Black, Hispanic, Asian or Pacific Islander, and Others) had a higher rate of in-hospital complications, in-hospital procedures, mean LOS, and hospital charges compared to Whites. In contrast, Whites had a higher rate of in-hospital mortality, PC, and DNR. In multivariable analysis, all minorities had higher rate of MV, tracheostomy, transfusions, and gastrostomy compared to Whites, while Hispanics had higher rate of craniectomy and VP shunt; and Asian or Pacific Islander and Others had higher rate of craniectomy. Whites had a higher rate of in-hospital mortality, palliative care, and DNR compared to minorities. In mediation analysis, in-hospital mortality for whites remained high after adjusting with PC and DNR.

Conclusion

Minorities had greater utilization of lifesaving and life sustaining procedures, and longer LOS. Whites had greater utilization of palliative care, hospice, and higher in-hospital mortality. These results may reflect differences in culture or access to care and deserve further study.
Biotransformation to Produce the Anticancer Compound Colchicoside Using Cell Suspension Cultures of Astragalus vesicarius Plant Species
Authors: Zarev Yancho , Popova Pavlinka , Foubert Kenn , Apers Sandra , Vlietinck Arnold , Pieters Luc , Ionkova Iliana
Published: March 2019

This paper discusses the biotechnological process affected by means of plant suspension cultures, for production of colchicoside, the 3- O-glucosyl derivative of 3- O-demethylcolchicine. Colchicoside can be considered as an antitumoural prodrug which is activated after oral administration and may have more beneficial effects and a better toxicity profile (because of a slow-release effect) than colchicine. We have developed a green and efficient biotechnological method using colchicine, as a precursor, derived from its natural source G. superba seeds. Plant suspension cultures of Astragalus vesicarius were used to design a practical biotechnological platform to replace a methyl group at C-3 regiospecifically by a glycosyl moiety in colchicine. Using different concentrations of a colchicine-rich extract, the maximum enzymatic potential of Astragalus vesicarius suspension cells was achieved. According to quantitative HPLC-UV analysis, levels of 9.35 μmol/g DW colchicoside were achieved. This is the first report of region-specific glycosylation at C-3 of the aromatic ring A of the colchicine using plant suspension cultures.
Exploratory study on geodesic domes under blast loads
Authors: Rebelo Hugo Bento , Amarante dos Santos Filipe , Cismaşiu Corneliu , Santos Duarte
Published: March 2019

This article studies the feasibility of using geodesic domes as expeditionary protective structures, since they are fast-assembly lightweight structures and are able to withstand very heavy loads due to their specific geometry. A 6-m standard International Orginization for Standardization container is used as a benchmark structure for the study, which is developed using the nonlinear explicit code LS-DYNA. The blast simulations were performed with the Load Blast Enhanced option, using the phenomenological Johnson–Cook constitutive model to reproduce the behaviour of steel subjected to a large range of strain rates. The performance assessment of the protective structures under blast loading was based on the evaluation of the associated safety zones inside the protective shelter as well as on the characterization of the potential structural damage. With the additional insights provided by this article, it is possible to identify some of the competitive advantages shown by this type of structures which will hopefully foster new advances in the field.
Globalizing online learning: Exploring culture, corporate social responsibility, and domestic violence in an international classroom
Authors: Peterka-Benton Daniela , Benton Bond
Published: March 2019

The construction of a successful online collaboration between distinct cultural groups requires an informed cultural awareness. This is the exploration of such an online collaboration between American and Turkish Students. The focus of the shared student interaction was the concept of corporate social responsibility. As the concept is enacted differently in different cultures, this represented an ideal opportunity for topical student reflection and for cultural exploration. The approach utilized focused on relationship-building as a preface to content discussion based participant preferences suggested by relevant cultural research (e.g., Hofstede). Corporate social responsibility campaigns in the United States and Turkey focused on domestic violence were considered with an eye toward the distinctions between each. Results suggest positive student outcomes emerged from this approach. Implications for intercultural online learning and diversification of public relations curricula are considered.
Therapeutic dilemma in twin reversed arterial perfusion sequence
Authors: Aoyagi Yoko , Kai Kentaro , Sumie Masahiro , Fujiyoshi Naoki , Furukawa Yuichi , Narahara Hisashi
Published: March 2019

The dissemination of minimally invasive in utero surgery reduced the mortality of twin reversed arterial perfusion sequence, but the mortality of expectantly treated surgical candidates remains high. A 26-year-old, non-parous, Japanese woman at 13 weeks of gestation had been diagnosed with twin reversed arterial perfusion sequence and was judged as a surgical candidate for radiofrequency ablation. However, she did not undergo surgery because of the anatomical location of the acardiac twin. At 18 weeks of gestation, the blood flow to the acardiac twin disappeared spontaneously. The pump twin began to demonstrate fetal growth retardation during the third trimester. The patient delivered a 1891 g female at term. We macroscopically identified the cause of the fetal growth retardation as velamentous insertion of the umbilical cord and microscopically diagnosed the acardiac twin with acardiac acephalus. We should give the same attention to the management of post–twin reversed arterial perfusion sequence as twin reversed arterial perfusion sequence itself.
A Comparative Analysis of Surgical Wound Infection Methods: Predictive Values of the CDC, ASEPSIS, and Southampton Scoring Systems in Evaluating Breast Reconstruction Surgical Site Infections
Authors: Campwala Insiyah , Unsell Kayla , Gupta Subhas
Published: March 2019

Infection is the most significant complication in breast reconstruction surgery. While the Center for Disease Control and Prevention (CDC) is the most prevalent tool for surgical site infection (SSI) diagnosis, ASEPSIS and Southampton scoring methods have been speculated to be more sensitive. The ASEPSIS scoring system previously demonstrated much better interrater reliability than the CDC. We sought to assess the predictive value of various wound scoring methods in breast reconstruction SSIs. A retrospective analysis of all single-institution breast reconstruction infections from January 2013 to June 2016 was performed. Patients’ postoperative wound-related complications were collected. Southampton, CDC, and modified ASEPSIS scores—extended to 30 postoperative days—were calculated. Relative predictive values for implant-based reconstruction were evaluated. Among the 22 reviewed cases, ASEPSIS scores greater than 30 resulted in a more than 50% rate of implant-based breast reconstruction failure. There was a significant positive correlation between ASEPSIS score and failure rate ( P = .022). A Southampton classification of B—minor complication (60% failure)—had a greater associative risk of reconstruction failure than a classification of C—major complication (23% failure)—or classification of D—major hematoma (0% failure). The CDC score had no predictive value of success versus failure of reconstruction. While the CDC criteria and Southampton scoring systems demonstrated little clinical use, the ASEPSIS scoring system shows substantial predictive value for breast reconstruction SSIs. New procedure protocols should be implemented to require detailed surgical notes including the proportion of the wounds affected by inflammatory responses to allow for easier wound score calculation by these alternate scoring systems.
An experimental study on the digital precision of internal fixation via the sinus tarsi approach for calcaneal fractures
Authors: Xu Jing , He Zaopeng , Zhang Guodong , Chen Yongshao , Wei Chunrong , Zheng Yudong , Lin Haibin , Li Wei , Huang Wenhua
Published: March 2019

Objective:

To investigate the effectiveness and accuracy of internal fixation of calcaneal fractures with a three-dimensional (3-D) printing navigation module via the sinus approach.

Methods:

Eleven lateral lower extremity specimens were used in the experiment and divided into the digital design (DD) group ( n = 11) and the real surgery (RS) group ( n = 11). For the DD group, thin-section computed tomography (CT) scans, virtual fracture modeling, virtual bone plate fixation, sinus occlusal module design, and navigation module design were performed for the cadaver specimens. A 3-D navigation module was printed using a 3-D printer. For the RS group, the sinus approach incision was made, and the navigation module was used to assist the placement of screw fixation and anatomically locked bone plate fixation. Thin-layer CT scans, 3-D reconstructions, and reconstruction of the nail paths were performed in the RS group and 3-D registered with the DD group. 3-D coordinate values for the screw entry and exit points in the RS and DD groups were recorded, and the corresponding offset values of the screw points were calculated. The number of qualified nails at different accuracy levels was counted. The χ2 test was used to compare the data for the DD and RS groups to obtain the accuracy level for both groups when p > 0.05, which is the critical value for experimental accuracy.

Results:

A total of 11 bone plates were placed and 120 screws were locked. None of them protruded from the inferior articular surface. The screw entry and exit point offsets were 1.71 ± 0.11 mm and 3.10 ± 0.19 mm, respectively. When the accuracy requirement for the entry point was 3.8 mm, there was no statistically significant difference between the two groups ( p > 0.05). Similarly, the accuracy of the exit point of the screw could only reach 6.6 mm.

Conclusion:

Internal fixation of calcaneal fractures via the sinus tarsi approach with an anatomical locking plate based on the 3-D printing navigation module can achieve accurate screw placement and good overall internal fixation.
Bilateral Facial Weakness in a Syndromic Patient: Cadaveric Fascia Lata Graft for Lower Lip Deformity Correction
Authors: Silan Francesco , Consiglio Fabio , Dell’Antonia Francesco , Vidali Alessandra , Rizzetto Christian , Berna Giorgio
Published: March 2019

Fazio-Londe syndrome is a rare neurodegenerative disorder caused by riboflavin transporter deficiency. Clinical presentation includes variable hypotonia or muscle weakness, sensory gait ataxia, optic atrophy, sensorineural hearing loss, and bulbar palsies. We described the case of a 37-year-old patient with a suspected Fazio-Londe syndrome who was referred to us for oral incompetence with dysarthria and drooling and impaired facial expression. First, we provided static sling suspension of the lower lip with Silhouette sutures (Silhouette Lift). Due to recurrent sutures exposure, we had to remove the sutures and insert a bilateral fascia lata graft to resuspend the lower lip. Two months postoperatively, the patient had good oral competence and there were no complications. In our opinion, this is a simple and minimally invasive procedure that can restore the right lower lip position in challenging patients.
Prepectoral Reconstruction Using Alloderm Matrix in a Patient With Unilateral Poland Syndrome: A Case Report and Review of Literature
Authors: Halyk Laura , Card Annika
Published: March 2019

Poland syndrome is characterized by unilateral hypoplasia of the breast, chest wall deformities, and arm and hand deficits. The syndrome has a large spectrum with degrees of severity and presentation. This congenital condition has been well reported in literature with a broad range of options for surgical correction. We report a 15-year-old female with typical features of Poland syndrome and the reconstructive efforts undertaken to preserve pectoralis function and a normal chest wall while creating a natural-looking breast with the prepectoral method of breast reconstruction using acellular dermal matrix.
Complementary and Alternative Medicine for Menopause
Authors: Johnson Alisa , Roberts Lynae , Elkins Gary
Published: March 2019

Menopause is associated with problematic symptoms, including hot flashes, sleep problems, mood disorders, sexual dysfunction, weight gain, and declines in cognitive functioning. Many women seek complementary and alternative medicine (CAM) for symptom management. This article critically reviews the existing literature on CAM treatments most commonly used for menopausal symptoms. Electronic searches were conducted to identify relevant, English-language literature published through March 2017. Results indicate that mind and body practices may be of benefit in reducing stress and bothersomeness of some menopausal symptoms. In particular, hypnosis is a mind-body intervention that has consistently shown to have a clinically significant effect on reducing hot flashes. Evidence is mixed in regard to the efficacy of natural products and there are some safety concerns. Health care providers should consider the evidence on CAM in providing an integrative health approach to menopausal symptom management.
RETRACTED ARTICLE: Melatonin enhances TNF-α-mediated cervical cancer HeLa cells death via suppressing CaMKII/Parkin/mitophagy axis
Authors: Zhao Qinghe , Wang Wuliang , Cui Jinquan
Published: March 2019

Background

Tumor necrosis factor-α (TNF-α) immunotherapy controls the progression of human cervical cancer. Here, we explored the detailed molecular mechanisms played by melatonin in human cervical cancer (HeLa cells) death in the presence of TNF-α injury, with a particular attention to the mitochondrial homeostasis.

Methods

HeLa cells were incubated with TNFα and then cell death was determined via MTT assay, TUNEL staining, caspase ELISA assay and western blotting. Mitochondrial function was detected via analyzing mitochondrial membrane potential using JC-1 staining, mitochondrial oxidative stress using flow cytometry and mitochondrial apoptosis using western blotting.

Results

Our data exhibited that treatment with HeLa cells using melatonin in the presence of TNF-α further triggered cancer cell cellular death. Molecular investigation demonstrated that melatonin enhanced the caspase-9 mitochondrion death, repressed mitochondrial potential, increased ROS production, augmented mPTP opening rate and elevated cyt-c expression in the nucleus. Moreover, melatonin application further suppressed mitochondrial ATP generation via reducing the expression of mitochondrial respiratory complex. Mechanistically, melatonin augmented the response of HeLa cells to TNF-α-mediated cancer death via repressing mitophagy. TNF-α treatment activated mitophagy via elevating Parkin expression and excessive mitophagy blocked mitochondrial apoptosis, ultimately alleviating the lethal action of TNF-α on HeLa cell. However, melatonin supplementation could prevent TNF-α-mediated mitophagy activation via inhibiting Parkin in a CaMKII-dependent manner. Interestingly, reactivation of CaMKII abolished the melatonin-mediated mitophagy arrest and HeLa cell death.

Conclusions

Overall, our data highlight that melatonin enhances TNF-α-induced human cervical cancer HeLa cells mitochondrial apoptosis via inactivating the CaMKII/Parkin/mitophagy axis.
Free versus pedicled flaps for reconstruction of head and neck cancer defects: A systematic review
Authors: Gabrysz-Forget Fanny , Tabet Paul , Rahal Akram , Bissada Eric , Christopoulos Apostolos , Ayad Tareck
Published: March 2019

Objective

The present review focuses on comparative studies of reconstruction with free flaps (FF) versus pedicled flaps (PF) after oncologic resection.

Method

A systematic review was developed in compliance with PRISMA guidelines and performed using the Pubmed, Medline, EMBASE, Amed and Biosis databases.

Results

A total of 30 articles were included. FF are associated with a longer operative time, a higher cost and a higher incidence of postoperative revisions compared to PF. FF are associated with a longer stay at the intensive care unit than the supraclavicular artery island flap (SCAIF) and with a more extended hospital stay compared to the submental island flap (SMIF). FF are associated with fewer infections and necrosis compared to the pectoralis major myocutaneous flap (PMMF).

Conclusion

The comparison of both type of flaps is limited by the inherent design of the studies included. In sum, FF seem superior to the PMMF for several outcomes. SMIF and SCAIF compare favorably to FF for some specific indications achieving similar outcomes at a lower cost.
Loop underlay tympanoplasty for anterior, subtotal and total tympanic membrane perforations: A retrospective review
Authors: Barake Rana , El Natout Tamer , Bassim Marc , El Natout Mohammad Ali
Published: March 2019

Background

The study aims at reporting our experience with loop underlay tympanoplasty, a modification of the underlay technique previously reported, for the reconstruction of anterior, subtotal or total tympanic membrane perforations.

Methods

A retrospective review of charts of patients who have undergone loop underlay tympanoplasty from January 2002 to January 2012 was performed. One thousand one hundred patients were included. Hearing test results preoperatively and postoperatively were reported. On follow up visits, the closure of the tympanic membrane perforation and the improvement of hearing compared to preoperative measurements with absence of complications were considered as successful outcomes of the surgery.

Results

At the three-month follow-up visit, the perforation closure rate was found to be 99.3% and Air-Bone Gap closure rate to less than 10 dB was 99.5%. The complication rate, including post-operative infection, was 0.72%.

Conclusion

The loop underlay technique combines advantages of both underlay and overlay techniques with excellent postoperative outcomes.
Rosjoznawstwo = kulturoznawstwo. Rosjoznawstwo na Uniwersytecie Jagiellońskim (1990–2017)
Authors: Suchanek Lucjan
Published: March 2019

RUSSIAN STUDIES = CULTURAL STUDIES. RUSSIAN STUDIES AT THE JAGIELLONIAN UNIVERSITY IN KRAKOW (1990–2017)The subject of the article is the history of the development of Russian cultural studies (RCS) in Krakow, initiated at the turn of the 20th and 21st centuries. The collective achievement created by scientists with mainly philological backgrounds over the years have been enriched and expanded by content from other scientific disciplines. This ultimately formed a multidisciplinary face of RCS. In the article, the most important figures and publications are mentioned that contributed to building a significant curriculum of Russian cultural studies in Krakow. The specificity of the curriculum, its multidimensionality and humanistic- social approach make it a rich reservoir of knowledge which helps one to understand culture in its Russian form.
Design interventions to repair migrants’ mental well-being: The ‘Culture in Mind’ healing space
Authors: Kalantidou Eleni
Published: March 2019

The intention of this article is to present the transformation of a space that houses a migrant-oriented community service with a focus on mental health and well-being (Culture in Mind) into an inviting milieu, which fosters healing processes, intercultural understanding and community empowerment in Brisbane, Australia. This project, which was formed as a case study, is described through its ideation phase, the installation methods, the sourcing and use of reclaimed materials as well as the methods employed for the collection of data, including interviews conducted for the evaluation of the design interventions. In like manner, the outcomes of the data analysis are discussed in conjunction with evidence provided by relevant studies and photos collected through the documentation process. The final part of the article is dedicated to arguing the necessity of different understandings of mental health according to non-western cultural backgrounds so as to inform the design of mental health services and physical settings and enhance sentiments of privacy, safety and dignity for migrant patients.
The journey through imagination: Francesca
Authors: Ippolito Valentina
Published: March 2019

Over the past decade, Romanian New Wave (Noul Val) has emerged as a vital component of European cinematic identity, with a number of its films representing stories of diasporic migration within an historical context set before and after Romania’s accession to the European Union. This migration cinema has been a flourishing artistic tool for social criticism, bringing on-screen stories of crime, social degradation and corruption connected to journeys away from Romania, a number of which have Italy as their target. Recent scholarship has identified sociopolitical themes associated with Romanian migration cinema and the cinematic representation of marginalized identities. However, critical attention has so far overlooked the analysis of the recurrent presence of Italy in Romanian films, especially as an index of the extent to which the voice of the Romanian migrant is allowed to penetrate contemporary cinematic narratives. To address this critical gap, this article examines the expressive modes used by Noul Val director Bobby Paunescu to represent Italy in his film Francesca. Experienced by characters as a dead end for utopian desire, this article illustrates how the journey to Italy culminates in failure, disenchantment and grief.
Maltrato escolar, práctica pedagógica y lenguaje
Authors: Castañeda Rojas Giovanny
Published: March 2019

En este artículo se presentan algunos resultados de la investigación titulada “Configuración del maltrato en las relaciones profesor/estudiante”, que tuvo como propósito comprender el maltrato que ejercen los profesores sobre los estudiantes y que deja un saldo negativo a nivel académico, emocional y social, tanto para los estudiantes como para los mismos profesores, quienes en muchos casos se ven afectados por las respuestas violentas que reciben de sus propios estudiantes. Así mismo, los efectos desfavorables del maltrato para el clima escolar que se ven traducidos en las relaciones de conflicto entre colegas y de estos con padres de familia y directivos, además de las implicaciones negativas para la escuela y el sistema educativo que muchas veces se siente impotente debido a la complejidad de esta expresión de la violencia escolar en la cual son los profesores y la misma escuela quienes en muchas ocasiones se constituyen en los victimarios. Para alcanzar los objetivos planteados, la investigación emplea una metodología cualitativa, enfoque Investigación Acción Participación- IAP y el modelo de los Núcleos de Educación Social –NES. La población participante estuvo conformada por estudiantes, profesores, directivos y padres de familia de 3 colegios públicos de la ciudad de Bogotá en tres localidades. Para el trabajo con profesores y directivos se emplearon entrevistas a profundidad. Con los padres se realizaron grupos focales y con estudiantes se efectuaron 3 NES con 24 sesiones de trabajo que abarcaron 4 meses aproximadamente. A manera de balance, se ponen en discusión las posibles relaciones entre el maltrato, la práctica pedagógica y el lenguaje a través del cual se genera violencia en la escuela.
Análise didática de uma atividade lúdica sobre a "instabilidade nuclear"
Authors: Batista Carlos Alexandre , Siqueira Maxwell
Published: March 2019

Um dos grandes desafios para a inserção da Física Moderna e Contemporânea (FMC) no Ensino Médio (EM) perpassa pelas dificuldades docentes de ensinar seus conceitos, sem atribuir exclusividade à resolução de exercícios de livros didáticos. Contribuindo para superá-lo, o artigo evidencia aspectos didáticos que uma Atividade Lúdica sobre a “Instabilidade Nuclear” (ALIN) fornece para o ensino-aprendizagem de conceitos de FMC. A análise fundamenta-se na Teoria das Situações Didáticas (TSD). A ALIN é parte integrante de uma sequência de ensino-aprendizagem sobre a Radioatividade (SEAR), desenvolvida, operacionalizada e avaliada como fruto de pesquisa. A SEAR foi implementada por um professor de Física em sua turma de curso Técnico em Informática (nível médio), em um Instituto Federal de Educação Ciência e Tecnologia de uma cidade brasileira do Sul da Bahia. Os dados, incluindo as falas do professor e de 10 dos 25 estudantes, foram obtidos com o recurso da videografia, transcrição dos diálogos e registros de imagens fotográficas. O recorte é justificado por ser, sob a lente da TSD, o mais significativo. Ele evidenciou na ALIN os aspectos didáticos de caráter lúdico e de regras preconizadas por questões e comentários, associados aos conceitos da Radioatividade. Relacionados à concepção de contrato didático e seus elementos constituintes fundamentais, esses aspectos são considerados “cláusulas implícitas de um contrato didático”, que podem ser transferidas para desenvolver a ALIN em outros contextos de ensino. Os resultados denotam que a atividade é um instrumento em potencial que cria condições para o ensino da Radioatividade. Todavia, é necessário que professores e estudantes aceitem o desafio de realizá-la atentando para os sistemas de obrigações vinculados a relação didática. Consideramos que a atividade pode ajudar na reflexão de atitudes positivas durante o processo de ensino-aprendizagem de conceitos da FMC em ambientes reais de sala de aula.
Affective power of vandalism: youth vandal practices within the concept of affective labor
Authors: Simonova Irina A.
Published: March 2019

The purpose of the article is an adaptation of the affective labor concept as a method for analyzing vandalism among young people. The article examines youth vandalism as a form of affective labor and identifies two types of effects. The first type deals with the experiences of the vandals themselves which cause the new subjectivity and collectivity; the second type refers to the effects experienced by the users of vandal-altered spaces: they begin to feel differently because the damage can seriously change the status, value, user qualities of the urban environment and the emotions it induces on inhabitants.

The paper analyzes youth vandalism as a strategy which not only transforms the urban space visually (physically) but also consciously constructs the affects transforming the subjectivity of young people, social positions and community forms of both the vandals themselves and the users of the city. This approach, reflecting the strategic nature of the young people’s vandal activity, shows that vandal practice should be understood as the practice of space occupation, its appropriation, its de- and reconstruction and should be based on social topology and general ideas of actor-network theory. The socio-philosophical conclusions in the paper are illustrated by the results of interviews involving 17 participants from 7 youth communities conducted in summer and autumn 2017 in Yekaterinburg. The photographs of the damaged urban spaces in various city districts were also taken; the data were mapped, and the photo database was marked according to geographical location and types of damaged buildings. This helped to draw certain conclusions about the youth vandalism phenomenon. The article outlines the prospects for the use of the proposed methodology in the analysis of vandal damage and in urban vandalism prevention activities.

Acknowledgement. The research is funded by the Russian Science Foundation (project no. 17-18-01278).
Time-Series InSAR Analysis of the Small Baseline Subset to Estimate Surface Deformation at Mt. Bromo Indonesia
Authors: Arbad Arliandy Pratama , Takeuchi Wataru , Aoki Yosuke , Ardy Achmad , Jamilah Mutiara
Published: March 2019

Penginderaan jauh kini memainkan peranan penting dalam pengamatan perilaku gunung api. Penelitian ini bertujuan untuk mengamati deformasi permukaan Gunung Bromo, yang terletak di Jawa bagian Timur, Indonesia, yang masuk dalam rangkaian sistem volkanik di Taman Nasional Bukit Tengger Semeru (TNBTS). Penggunaan algoritma SAR Interferometry (InSAR) yang disebut sebagai pendekatan Small Baseline Subset (SBAS) memungkinkan perancangan peta kecepatan deformasi rata-rata dan and peta time series displacement di wilayah kajian. Teknik SBAS yang biasa menghasilkan rangkaian observasi tahap interferometrik. Ini tercatat sebagai kombinasi linear dari nilai fase SAR  scene untuk setiap pixel secara tersendiri. Analisis yang dilakukan terutama berdasarkan 22 data SAR data yang diperoleh melalui sensor ALOS/PALSAR selama kurun waktu 2007–2011. Beberapa penelitian menunjukkan bahwa kemampuan analisis InSAR dalam menyelidiki siklus gunung api, terutama Gunung Bromo yang memiliki karakteristik erupsi stratovolcano dalam satu hingga lima tahun. Analisis hasil memperlihatkan adanya kemajuan dari kajian sebelumnya akan InSAR wilayah tersebut, yang lebih fokus  kepada deformasi yang berpengaruh kepada kaldera. Hal ini menunjukkan bahwa penelitian ini bisa diimplementasikan pada manajemen risiko atau manajemen infrastruktur
Evaluasi Kemantapan Permukaan Jalan Berdasarkan International Roughness Index Pada 14 Ruas Jalan di Kota Yogyakarta
Authors: Pembuain Ardilson , Priyanto Sigit , Suparma Latif Budi
Published: March 2019

Jalan yang memiliki kekasaran (roughness) permukaan yang buruk dapat menyebabkan ketidaknyamanan bagi pengguna jalan, kecelakaan lalu lintas, peningkatan beban dinamis pada permukaan jalan sehingga mempercepat proses kerusakan jalan, serta kerusakan kendaraan. Penelitian ini bertujuan untuk mengevaluasi kemantapan kondisi jalan berdasar nilai international roughness index (IRI). Evaluasi kondisi kemantapan jalan dilakukan pada 14 ruas jalan di Kota Yogyakarta, dengan perincian 4 ruas jalan arteri sekunder dan 10 ruas jalan kolektor sekunder. Data nilai kekasaran permukaan jalan (IRI) diperoleh dengan menggunakan alat NAASRA roughness meter yang mengacu pada SNI 03-3426-1994. Evaluasi kemantapan kondisi jalan dilakukan dengan membandingkan nilai IRI hasil survei dan batasan nilai IRI yang ditetapkan oleh Direktorat Jenderal Bina Marga. Hasil penelitian menunjukkan 14 ruas jalan yang dievauasi 64% dalam kondisi sedang dan 36% dalam kondisi baik. Dari ke-14 ruas jalan tersebut, ruas jalan Sisingamangaraja, Lowanu, dan Sugeng Jeroni memiliki nilai IRI tertinggi secara bururutan sehingga ketiga ruas jalan tersebut lebih diprioritaskan untuk mendapatkan penanganan
Implementation of Forest Certification in Brazil, Spain And Portugal: An Analytic Hierarchy Process (AHP) Application
Authors: Alves R.R. , Fraj-Andrés E. , Rojo-Alboreca A. , Gracioli C.R.
Published: March 2019

Forest certification is an important mechanism for the legitimation of environmental practices in the sustainable forest management. Its basis are the forest management standards, which represent the guidelines for defining sustainable forest management through a hierarchical structure (principles, criteria and indicators), which includes social, environmental and economic issues. The main certification systems in the world, FSC and PEFC, have adopted this structure in their forest management standards. This work aims to evaluate the perception of experts in Brazil, Spain and Portugal regarding the level of difficulty to implement forest certification applying the Analytic Hierarchy Process (AHP). The principal results indicated that, in general, the principles related to environmental aspects are considered the most complicated to comply, the social aspects are much more difficult to achieve in the case of Brazil, and the economic aspects are not considered as an important problem in any of the three countries.
User education, adjustment factors and use of online databases by postgraduate students in Nigeria
Authors: Ajala Anuoluwa Maria , Adetimirin Airen
Published: March 2019

Postgraduate students use online databases for various academic activities. However, past studies have revealed low utilisation of online databases by postgraduate students in Nigeria. The general objective of this study was to examine the influence of user education and adjustment factors (perceived enjoyment and objective usability) on use of online databases by postgraduate students of four private universities in southwest Nigeria. A descriptive survey research design of the correlational type was used, and the population was comprised of 1,067 postgraduate students in four private universities. A sample size of 513 was selected through a purposive sampling technique. Data was collected using a questionnaire and analysed using descriptive and inferential statistics. Findings revealed varying degrees of usage, perceived enjoyment and objective usability of online databases among the respondents. The study established a significant relationship between: user education and use of online databases; perceived enjoyment and use of online databases; and objective usability and use of online databases. User education, perceived enjoyment and objective usability therefore influenced the use of online databases by the postgraduate students of the four universities.
System-Dynamic Modeling of Network Information Operations
Authors: Minaev Vladimir A. , Sychev Mikhail P. , Vaits Ekaterina V. , Bondar Konstantin M.
Published: March 2019

Introduction. Information-technical and information-psychological influences are the main negative factors affecting the information security according to the Information Security Doctrine of the Russian Federation. Therefore, modeling, evaluating and forecasting information influences on social groups and organizing adequate information counteraction are urgent tasks of management.
Materials and Methods. The system-dynamic models of information influences in social networks and groups are considered. Their application for purposes of counteraction to information terrorism and extremism is proved. The description in the form of flowcharts is given. Systems of differential equations are presented. Experiments with models using the advanced simulation platform Anylogic have been carried out.
Results. In a sample of Russian settlements based on the cluster analysis there have been found homogeneous typological groups that differ in the average time of disseminating information in social networks. Based on Gibbs’s Postulate, the system-dynamic model of information influences on students has been successfully tested.
Discussion and Conclusion. The high consistency of simulation results with empirical data (determination coefficients of at least 90 %) is shown. Models allow forecasting the information influence and information counteraction and playing different scenarios for the dynamics of these processes.
Revisión de conceptos: embarazo en adolescentes y la experiencia en el control prenatal
Authors: Cruz Naranjo Maria Cristina , Lastre Amell Gloria Elena , Lastra Lamby Noraida
Published: March 2019

Introducción: Revisar investigaciones sobre conceptos de embarazos en adolescentes y experiencia de gestantes adolescentes en el momento de asistir al control prenatal en las instituciones prestadoras de salud, por parte de los profesionales de la salud (médico, enfermera), en el programa de promoción y prevención.

Métodos: Estudio de carácter cualitativo bajo el enfoque documental; mediante en el cual se revisaron investigación y estudio referentes al tema.

Discusión: Durante el proceso de revisión documental, se evidenció que las jóvenes en gestación al momento de asistir a una institución prestadora de salud, muestran una serie de sentimientos que van de la emoción hasta el miedo, como consecuencia del estado en que se encuentran.

Conclusión: Es de ahí la importancia de insistir en una atención temprana del embarazo de adolescente mediante un control prenatal adecuado, llevado a cabo por personal profesional entrenado en la atención de adolescentes permite disminuir los riesgos biológicos, tanto para la madre como para el producto.
La internacionalización de las entidades locales y estrategia de planeación: una oportunidad para el desarrollo territorial
Authors: Janer Quiñones Jeffrey , Gautier Ancelin
Published: March 2019

En las últimas décadas, las entidades territoriales van desarrollando políticas públicas con el fin de favorecer su inserción en la escena internacional y propiciar un desarrollo efectivo a nivel local a partir de aquella gestión internacional. En el presente trabajo, se aborda por una parte las discusiones y debates teóricos actuales en torno a la paradiplomacia, y más específicamente a la diplomacia de las ciudades en cuanto a su papel en las estrategias de planeación territorial. Luego, se pretende llevar un análisis desde el ejemplo del Gobierno del Atlántico en relación a su acción internacional y las potencialidades que tienen sus iniciativas a nivel de este departamento caribeño.
A Influência de uma Rede Social nos Padrões de Alimentação de Usuários e Profissionais de Saúde Seguidores de Perfis Fitness
Authors: Almeida Simone Gonçalves de , Almeida Andréa Gonçalves de , Dos Santos André Luiz , Silva Marcela Leandro
Published: March 2019

Manifestações socioculturais que vêm alcançando um grande espaço, atualmente, são as redes sociais e o papel que estas exercem no comportamento das pessoas é cada vez mais preponderante. O objetivo deste trabalho é verificar uma rede social quanto ao padrão de alimentação de usuários e de profissionais de saúde seguidores de perfis fitness. O grupo de estudo foi constituído por 499 usuários seguidores de perfis fitness e 53 nutricionistas. Como ferramenta de coleta de dados, foram elaborados dois questionários distintos: um para cada grupo, contendo perguntas alternativas, fechadas e relacionadas ao tema do estudo. Junto aos usuários seguidores de perfis fitness foi possível verificar os aspectos motivacionais ligados à mudança dos hábitos alimentares. Os resultados permitiram concluir que a grande maioria dos participantes acredita na influência que as postagens exercem nos hábitos da sociedade atual. Postagens fitness no Instagram podem estar relacionadas à incidência de transtornos estético-alimentares, como: anorexia, bulimia, vigorexia e ortorexia. Fotos comparativas parecem direcionar a alimentação, principalmente, para objetivos estéticos, deixando saúde e qualidade de vida em segundo plano. Para se obter um maior sucesso no Instagram, é necessário que profissionais de saúde conheçam melhor o seu público-alvo e reforcem a importância do papel do profissional nas escolhas alimentares. Palavras-chave: Redes Sociais. Instagram. Hábitos Alimentares. Perfis Fitness. AbstractManifestations that haveachieved a great space currently are social networks and the role they play in people's behavior. The objective of this study is to investigate the influence of social network Instagram in the pattern of power users followers of fitness profiles. The study group consisted of 499 followers of  user fitness profiles and 53 nutritionists. As data collection tool two different questionnaires were prepared, one for each group containing alternative questions, and closed related to the study subject. Together with the followers of  profiles fitness it was possible to verify the motivational aspects of changing eating habits. The results allowed to include that the great majority of the participants believe in the influence that the postings exert on the habits of the current society. Posts of physical fitness on Instagram may be related to the incidence of aesthetic eating disorders, such as anorexia, bulimia, vigorexia and orthorexia. Comparative photos seem to direct food mainly for aesthetic purposes, leaving health and quality of life in the background. To achieve greater success on Instagram, health professionals need to better understand their target audience and reinforce the importance of the professional's role in food choices. Keywords: Social Networks. Instagram. Eating Habits. Fitness Profiles.
Türkiye Florası İçin Yeni Dianthus (Caryophyllaceae) Kayıtları
Authors: HAMZAOĞLU Ergin , KOÇ Murat
Published: March 2019

Ardahan’dan toplanan Dianthus
azkurensis Sosn. ile Kayseri, Malatya
ve Mersin’den toplanan D. orientalis
Adams subsp. aphanoneurus Rech.f.
Türkiye florası için yeni kayıt olarak tanıtıldı. Ayrıca, taksonların detaylı
betimlemeleri, yayılışları ve resimleri verildi.
Pequeño esbozo te´orico para el estudio del derecho
Authors: Romano Burgos Francisco , Riobó Muto Carmen Cristina
Published: March 2019

El estudio del Derecho, el análisis del mismo, comprender su función, es un ejercicio que vi no es nada nuevo, el gran problema es la falta de interés por dichos ejercicios, año a año se toma otra muestra del experimento, del ejer- cicio, preguntar en primer año y en quinto, de igual manera, "¿qué es el derecho?" Es entonces el fin de este artículo, incentivar la duda, el interés por la teoría jurídica, un llamado a rumiar el Derecho, a pensarlo desde nuestras subjetividades
Nuestra primera experiencia como semilleristas en investigación
Authors: De la Parra Molina Katerin , Vélez Barrachaldo Daniela
Published: March 2019

No recordamos con precisión si fue la primera o segunda semana de nuestros estudios académicos en la Facultad de Derecho, en la Universidad Libre Sede Cartagena, cuando el Docente de Introducción al Derecho, nos manifestó que en la contemporaneidad, en el estudio de profesiones liberales y otras disciplinas de las ciencias sociales, para el caso específico de los estudiantes de derecho, el abogado que no investigaba, era menos abogado. Hoy, no sabemos si lo hizo por incentivarnos o porque fuera verdad, pero de la poca experiencia obtenida un año después que llevamos visitando el Centro de Investigaciones y haber pasado por varias experiencias en investigación, podemos afirmar que ser estudiante simple en la academia y agregarle el paso por el Centro de Investigaciones, nos hace diferentes o con un valor agregado que nunca hubiéramos obtenido calentando solo la silla del aula de clases.
Las bandas criminales frente al ordenamiento jurídico penal colombiano, "caso: clan usuga''
Authors: Pardo Sotomonte Jhon Tibaldo , Barrera Deisy Caterine , Espinosa Luis Gustavo
Published: March 2019

Problema, los operadores judiciales se enfrenten a delitos y crímenes de sistema. Se trata de hechos atroces no aislados, sino articulados a actores colectivos, en un contexto determinado. Objetivo. Determinar el estatus de las bandas criminales ubicados en los territorios de los grupos paramilitares y rebeldes y que realizan las mismas actividades delincuenciales de estos grupos mencionados. Metodología. Enfoque. Socio Jurídico que busca la práctica del derecho penal sobre las bandas criminales. Tipo de investigación. Descriptivo que busca especificar las propiedades de estas bandas criminales. Método. Teórico que aplica la inducción y deducción. Resultados. Las bandas criminales BACRIM no cuadrarían con las características propias de un grupo armado ilegal o Rebelde. Los Crímenes de Lesa Humanidad son actos generalizados (contra gran cantidad de víctimas) y sistemáticos (con arreglo a un plan o una política); actos que son realizados por autoridades del Estado o por particulares y sobre todo están dirigidos contra la población civil. Conclusiones. Hay un vacío en el sistema penal colombiano que no ha permitido una reacción eficaz contra las bandas criminales, porque el sistema penal está montado sobre la base de una judicialización individual, y los crímenes de sistema, de guerra y lessa humanidad, por implicar más de 10 personas en un proceso generan demora en las audiencias y en los procesos y en algunos casos se vencen los términos.