bluuebunny/crossref_metadata_2025 huggingface dataset:
An Investigation into the Experiences of Teachers and Head Teachers in Relation to Government-Run Primary Schools: A Case of Lilongwe Urban
Authors: Chimowa Makarios Kizito , Maganga Stewart
Published: May 2024

The focus of this paper is on the experiences of teachers and head teachers in government- run schools in the Lilongwe Urban area. Three schools were focused upon: Mkwichi Primary School in Area 47; Mbinzi Primary School in Area 3, and Tsokamkanansi Primary School in Area 43. This study was exploratory in that there has been a paucity of research carried out in the urban schools of Malawi particularly those run by the government. The study further utilized the qualitative approach and among the methods utilized included semi- structured interviews and focus group discussions. In terms of the findings, the study found that in so far as inclusive education in urban schools is concerned, challenges do abound. These include the lack of specialist teachers trained in special needs including material required to assist teachers and head teachers with handling students of special needs. Among some of the propositions were for the government to provide them with resources needed to assist learners with special needs.
Evaluation of oxidative stress and inflammation in patients with polycystic ovary syndrome
Authors: Sen Berra , Gonultas Senem , Albayrak Ceren , Temur Sevval , Acar Ilgar , Ozkan Beyza Nur , Islek Havva Sevde , Yilmaz Muserref Banu , Kale Ebru , Guler Eray Metin
Published: May 2024

Objective Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine and metabolic disorder characterized by hyperandrogenism, hyperinsulinemia, and insulin resistance. The prevalence of PCOS is increasing worldwide. Although the etiology of this disease is currently unknown, it is thought to be closely related to inflammation and oxidative stress. Our study aimed to compare patients have PCOS to healthy volunteers and assess the changes in oxidative stress and inflammatory parameters in these patients.Methods Thirty patients between the ages of 18-45 diagnosed with PCOS and 30 healthy volunteers with the same demographic characteristics were included in this study. Clinical parameters were measured using immunoassays. Oxidative stress biomarkers, total oxidant (TOS), total antioxidant (TAS), total thiol (TT), and native thiol (NT) levels were measured using photometric methods according to Erel’s method. The dynamic disulfide level (DIS) and oxidative stress index (OSI) were calculated using mathematical equations. Among the inflammatory parameters, values for interleukin (IL)-1β, IL-6, and tumor necrosis factor-α (TNF-α) were measured photometrically using commercially purchased kits.Results Moreover, TT and NT levels were lower in patients with PCOS compared to those in the healthy group statistically significantly (P<0.001). In addition, TAS, TOS, OSI, DIS, IL-1β, IL-6, and TNF-α levels were identified to be significantly higher in the patients with PCOS than those in the healthy group (P<0.001).Conclusion Evaluation of oxidative stress and clinical parameters used in the follow-up may be beneficial for the disease.
EMPREENDER O TURISMO NO ESTADO DE RONDÔNIA
Authors: Santos Clelia Ferreira  de Souza , Pinho Silvia Teixeira
Published: May 2024

O estudo foca no desenvolvimento do turismo em Mirante da Serra, Rondônia, destacando a necessidade de adaptação à era digital para atrair turistas. A metodologia inclui análises documentais, pesquisas de campo e observação direta, envolvendo dados de 10 empresas locais e 50 turistas. O objetivo foi transformar o município em um destino turístico inteligente através de estratégias que melhorem a infraestrutura digital e a experiência do turista. A pesquisa justifica-se pela oportunidade de revitalizar a economia local através do turismo, impulsionado pela digitalização, o que pode ampliar a visibilidade do município e melhorar a qualidade de vida dos residentes. A conclusão aponta para a importância da integração de tecnologias digitais na gestão turística, recomendando marketing digital, melhorias na infraestrutura e parcerias entre o setor público e privado para promover o turismo de forma sustentável e eficiente.
Una comparación de la tipificación del ciberdelito en Sudamérica
Authors: Vallejo Lara Jorge Santiago , Herrera Avilés Hillary Patricia , Ortega Campos Edwin Javier , Hidalgo Cajo Fredy Roberto
Published: May 2024

ha resultado en la tipificación de conductas delictivas en muchas legislaciones del continente americano. A pesar de esto, aún no se ha realizado un estudio completo sobre la realidad del delito informático en esta región, lo que dificulta la identificación y sanción de ciertas conductas cibernéticas que deberían ser tratadas como delitos independientes. Ante esta necesidad, se realizó una investigación que identifica los delitos informáticos tipificados en países con avances significativos en la materia, con el fin de reconocer falencias y vacíos presentes en las legislaciones del continente americano. Este trabajo de investigación se basó en publicaciones académicas y en el análisis realizado por los autores, utilizando métodos teóricos y empíricos, así como técnicas de entrevista y encuesta. Como resultado, se detallaron las conductas criminales ejecutadas con herramientas informáticas según la legislación americana, se identificaron las deficiencias existentes y se propuso una solución consistente en tipificar ciertas conductas cibernéticas como delitos independientes en los cuerpos jurídico-penales de Sudamérica, evitando su sanción bajo figuras tradicionales que no reflejan proporcionalmente el daño causado.
Representation of LGBTQIA in Bollywood Films
Authors: Gauram Bedse Sunita , Dugaje M. D.
Published: May 2024

India produces more Hindi films than any other country. Film portrayals of society mirror that culture, which in turn shapes social attitudes. Hindi film, also referred to as Bollywood, exhibits strong societal roots. The Delhi High Court authorized homosexual behavior in the last ten years, but the Supreme Court later declared it to be unlawful. These modifications mirror modifications in social views. In this paper, we focus on how homosexuality is portrayed in Hindi films in relation to social attitudes about both male and female homosexuality. In India, cultural and social values and attitudes towards sexuality have historically been positive. However, during the 200 years of British colonial rule, these values and attitudes towards homosexuality and homosexual men and women became extremely negative and even punishable, in line with the prevalent Victorian views on sex and sexual activity. The literature has identified and documented several sexual descriptions and identities. In this essay, we discuss a tiny number of Hindi movies that deal with homosexuality. These representations have generally been unfavorable. We discuss the reasons why this would be the case as well as the effect that these portrayals might have on viewers.
Biomarker Evaluation in Toxoplasma gondii-infected Patients
Authors: Sabah Wahaj Muwafaq , Abed Ali Mohammed
Published: May 2024

Back ground: This study used Toxoplasma IgG/IgM Antibody Rapid test to detect Toxoplasmosis in pregnant women and evaluate their lipid profile compared to a healthy control group.
The aim of the study: Serodiagnosis of parasite infection in aborted pregnant women using the rapid detection method. Evaluating the level of some immunological parameters in infected women such as IL17-A, TNA-, lactoferrin, shedding light on the lipid profile of parasite-infected women.
Patients and Methods: blood samples 240 were collected from aborted pregnant women attending some governmental hospitals and private medical clinics in some areas of Salah al-Din Governorate during the period from 1/7/2022 to 1/2/2023 and the required information was recorded according to a special questionnaire form.
The results: were analyzed statistically using the IBM SPSS Statistics (version 23) program, according to the t-test, at a significant level of p≤0.05. The results of Rapid Test (93 positive samples) 38.7% (divided into 80) 86.02% (positive samples for IgG, while 13 sample) 13.97% (positive for IgM and 147 negative samples) 61.25%. (There is a positive correlation between (LTF, IL-17A, TNF-a) (highly significant). The lipid profile analysis revealed a non-significant increase for each of cholesterol and high-density lipoprotein (HDL) in infected women, as Mean ± S.E concentration was (168.4±8.2 Pg/ml); (33±1.5pg/ml) respectively, compared to the control group, where the Mean ± S.E concentration was (141.6±15.5 Pg/ml); (28±3.09Pg/ml) respectively. While there was a non-significant decrease in each of LDL, very low-density lipoprotein (VLDL), and triglycerides in pateints group, as Mean ± S.E concentration was (80.6±3.7pg/ml); (45.4±1.07 pg/ml); (159.7±4 pg/ml), respectively, compared to the control group, where the average concentration was (84.3±5.3pg/ml); (48.6±2pg/ml) 161.3±6.7pg/ml) respectively.
Studying the Effect of Cholesterol and Activin a Hormone on Inducing Abortion in Pregnant Women
Authors: Ahmed Noor Hasan
Published: May 2024

The current study aimed to show the relationship between the levels of (activin-A hormone) and the concentration of lipids cholesterol) and the occurrence of some cases of Abortion and threatened pregnancy The study included 150 blood samples taken from aborted women and women with a threatened pregnancy, which is diagnosed by ultrasound scan and other methods such as clinical examinations and the history of the pregnant woman. Their ages ranged between (16-45) who visited Tikrit Teaching Hospital and private outpatient clinics. It was divided into three groups: The first included 50 blood samples from aborted women, 20 blood samples from women with a threatened pregnancy, and 20 blood samples from women with normal pregnancies as a control group. Blood samples were taken during the first trimester of pregnancy. The results of this study showed a significant increase in the concentration of (activin-A hormone) at a significant level (P ≤ 0.05) in the aborted women group .And women threatened with abortion compared with the control group, as well as a significant increase in the level of lipids (cholesterol) at a significant level (P ≤ 0.05)in the abortion group and the group of women threatened with abortion compared with the control group.
Vermicompost: Significance and Benefits for Agriculture
Authors: Abad Qiamudin , Shafiqi Shafigul
Published: May 2024

Vermicomposting is defined as the process of biodegradation and stabilization of organic materials, facilitated by the collaborative efforts of earthworms and mesophilic microorganisms. The activity of earthworms in vermicomposting results in the production of nutrient-rich vermicompost. This organic amendment is abundant in macro and micronutrients, vitamins, growth hormones, as well as enzymes like proteases, amylases, lipase, cellulase, and chitinase. Additionally, vermicompost harbors a diverse community of immobilized microflora. Even after being excreted by the worms, the enzymes in vermicompost persist in their ability to decompose organic matter, facilitating continued breakdown and nutrient release. The utilization of vermicompost in agricultural production brings forth a multitude of beneficial effects. These include decreased water requirements for irrigation, reduced susceptibility to pest and termite attacks, suppression of weed growth, and enhanced seed germination rates, accelerated growth and development of seedlings, as well as increased yield of fruits per plant in vegetable crops and a higher number of seeds per year in cereal crops. These advantages highlight the positive impact of incorporating vermicompost into agricultural practices, fostering sustainable and productive farming systems. The combination of earthworms and vermicompost presents a valuable opportunity to enhance horticultural production in a sustainable manner, reducing reliance on agrochemical inputs. Despite the numerous benefits associated with vermicompost, its widespread implementation and adoption are still relatively limited. This review aims to raise awareness and promote the understanding of this valuable local soil amendment.
INCIDENCE OF VULVO VAGINAL CANDIDIASIS IN YOUNG WOMEN; EXPERIENCE FROM A TERTIARY CARE HOSPITAL, KARACHI PAKISTAN
Authors: Raja Ayisha , Ahmed Abeera , Fareed Sindhu , Raja Namra Sohail , Tariq Ameera , Naqvi Syed Rehan Asghar
Published: May 2024

Objective: To study the incidence of Candida species in women of child bearing age presenting with abnormal vaginal discharge with and without symptom of pruritus vulvae.
Material and Methods: The descriptive cross sectional study was done from Feb 2022 to Jan 2023, HVS of 300 women were taken who presented with abnormal discharge from vagina and pruritus vulvae. Samples were taken for microbiological culture testing, after thorough assessment of pertinent gynecological and obstetric history. The cultures were followed up and the results recorded.
Results: The most frequently identified organism causing abnormal vaginal discharge was Candida albicans (62.27%) with pregnant women experiencing a 59.09% considerably higher prevalence rate. The study found that vaginal candidiasis symptoms were itching, white curdy vaginal discharge, burning, and dyspareunia. Candida albicans was found in 62.2% of cases, while non-albicans were found in 37.7%. Pregnant women accounted for 59.09% of positive cases, with 74 cases of Candida albicans and 56 cases of non-albicans. Non-pregnant women accounted for 40.9% of positive cases, with 63 cases of Candida albicans and 27 cases of non-albicans.
Conclusion:  Vulvo Vaginal Candidiasis associated with  C. albicans as well as non albicans species of Candida is very common in women of reproductive age especially in developing countries. Specific diagnosis of is important as it leads to prompt treatment with antifungal, thus improving patient's health and preventing chronicity associated with disease.
Keywords: High vaginal swab, Vaginal candidiasis, Vaginal discharge.
Correlation of nucleated red blood cell counts by Sysmex XN-1000 with conventional microscopy
Authors: Ishaque Nimrah , Batool Hijab , Saleem Ashja , Siddique Muhammad Usman , Imran Ayisha , Malik Nauman Aslam
Published: May 2024

Objective: To correlate the results of manual microscopy with that of Sysmex XN-1000 analyzers and to determine its diagnostic accuracy, taking microscopy as gold standard.
Material and Methods: The study was conducted at Chughtai Institute of Pathology from July 1st -December 31st, 2022. Nucleated Red Blood Cells (nRBCs) were manually enumerated against 100 White Blood Cells (WBCs) on peripheral smears and 511 such positive cases were included. 500 samples negative for nRBCs by manual microscopy were also included. These positive and negative samples were run on two Sysmex XN-1000 analyzers. A result of 0.3 and above nRBCs/100 WBCs on Sysmex XN-1000 was considered positive and less than 0.3 as negative. Mean values of both manual and automated methods were correlated.
Results: Our study mentioned nRBCs ranging from 0 to 1330 nRBCs/100WBCs by manual count. Compared with Sysmex XN-1000 analysis, the Deming regression analysis showed the mean difference between the two methods was 0.055 (95%CI: −0.015 to +0.124) (p>0.05 no proportional bias between two methods). The Sysmex XN produced an area under the curve, by ROC analysis, at 0.894 (P < .001). The overall sensitivity was (90.56%) (CI 87.56-92.98%), with few false-negative results. The overall specificity is (88.30%) (CI 85.20%-90.96%) due to few false positivity. Positive predictive value and negative predictive value were 88.26% (CI 88.54-90.52%) and 90.6% (CI 87.99-92.69%) respectively. Accuracy was 89.42% (CI87.35-91.25%).
Conclusion: Sysmex XN1000 analyzer is a highly sensitive and accurate instrument which can replace nRBCs enumeration using manual counting by conventional microscopy.
Keywords: Nucleated red blood cells, Hematology analyzer, Sysmex XN 1000, Manual microscopy
Hematological disorders on bone marrow examination in a tertiary care Centre
Authors: Bilal Hina , Ali Sundas , Kiani Maha Tariq
Published: May 2024

Objective: The aims of this study were to understand the range of different blood-related disorders diagnosed through bone marrow examination and to explore the connection between the age groups and genders of our patients with the subtypes of acute leukemia.
Material and Methods: This was a cross-sectional study carried over a period of one year from January 2022 to December 2022, in the department of Pathology, Pakistan Institute of Medical Sciences (PIMS), Islamabad. Analysis of bone marrow was conducted on patients referred with suspected blood-related disorders, and a total of 254 cases were incorporated into the study. We divided age into groups as 0-12 years (paediatric age group) and >12 years (adults) for comparison with subtypes of acute leukemias. Pearson chi-square test was applied. P value of <0.05 was considered statistically significant.
Results: The age range was from 05 months - 91 years with male: female ratio of 1.2:1. The prevalent non-malignant conditions identified during bone marrow examination were peripheral destruction/consumption of platelets (24.8%) followed by anemias (22%) and infection- related changes (9.4%). Among hematological malignancies, acute leukemias were the most frequent (22.8%), with chronic leukemias following at 7.1%. We also observed that Acute Lymphoblastic Leukemia was more common in Paediatric age group, while Acute Myeloid Leukemia was more frequent type of acute leukemia in adults (p <0.001).
Conclusion: The examination of bone marrow specimens is a key procedure for swiftly obtaining a confirmatory diagnosis for numerous hematological disorders, including hematologic malignancies.
Keywords: Anemia, Bone Marrow Trephine Biopsy, Bone marrow aspiration, Leukemia, Megaloblastic anemia
Pattern and burden of thrombocytopenia in chronic hepatitis C virus patients at a tertiary care hospital
Authors: Ayaz Qurat Ul Ain , Khanzada Farhan Ali , Sharif Anum , Farrukh Sarah , Akhtar Raana , Hamid Ambareen
Published: May 2024

Objective: To determine the frequency of thrombocytopenia in chronic Hepatitis C virus infection.
Material and Methods: This Descriptive cross-sectional study was conducted at department of Hematology, King Edward Medical University, Lahore from February 2023 to October 2023. A total of 143 patients of either gender with chronic Hepatitis C virus infection were included in the study. For every patient, a fresh 3 ml blood sample was collected by syringe using aseptic technique in a vacutainer containing EDTA. A complete blood count was carried out using Automated Hematology Analyzer and peripheral blood smear was prepared using Wright Giemsa stain to establish whether thrombocytopenia was present or not. Thrombocytopenia was assessed by Neubauer chamber.
Results: Age range in this study was from 18 to 65 years with mean age of 44.132±7.34 years, mean duration of HCV 12.685±4.53 months and mean platelet count was 238076.923 ± 100165.08/µL. Thrombocytopenia was seen in 37.1% patients.
Conclusion: Our results show that chronic hepatitis C infection is related to high frequency of thrombocytopenia. The higher the duration of disease process, higher is the risk of thrombocytopenia in these patients. This study highlights that identification by screening, timely diagnosis and treatment of Hepatitis C infection can prevent thrombocytopenia and its complications. Serial hematological follow up can play a pivotal role in such patients.
Keywords: Chronic hepatitis, Hepatitis C virus, Thrombocytopenia
Nonadverse COVID-19 evolution predictors: the CoNAE scale
Authors: Pulido-Herrero Esther , Larrea Nere , García-Gutiérrez Susana , Gallardo María S. , Gamazo-Del-Río Julio J. , Gascón María , Legarreta María-José , Villanueva Ane , Quintana José M.
Published: May 2024

Objetivos. Faltan herramientas para identificar a los pacientes con COVID-19 moderado o leve. El objetivo de este estudio fue identificar variables asociadas a la evolución no adversa y diseñar un modelo predictivo de evolución favorable en pacientes atendidos en servicios de urgencias hospitalarios (SUH) por infección por SARS-CoV-2. Métodos. Estudio de cohorte retrospectivo de pacientes con infección por SARS-CoV-2 que acudieron a alguno de los SUH de hospitales públicos de una área por una infección por COVID-19 entre el 1 de julio de 2020 y el 31 de julio de 2021. Los datos recogidos para este estudio incluyeron información sociodemográfica, comorbilidades basales y tratamientos, otros datos de antecedentes y registro de los signos vitales a la llegada (triaje) al SUH. Se utilizaron modelos de regresión logística multivariable multinivel para desarrollar los modelos predictivos. Resultados. Las personas que tuvieron resultados no adversos eran más jóvenes, mujeres, habían recibido dos dosis de la vacuna COVID-19 en el momento del estudio, tenían signos vitales (frecuencia cardiaca-presión diastólica/sistólica, temperatura y saturación de oxígeno) dentro de un rango normal al llegar al triaje del SUH, y no tenían ninguna de las siguientes comorbilidades: insuficiencia cardiaca, enfermedad coronaria, hipertensión arterial, diabetes, enfermedad hepática, demencia, antecedentes de tumores malignos o prescripción de corticosteroides orales sistémicos o inmunosupresores como medicación basal. El modelo tenía un área bajo la curva (ABC) de 0,8404 (IC 95%: 0,8342-0,8466). Conclusiones. Se ha desarrollado una escala de predicción de resultados no adversos que pueden ser útil como herramienta de triaje, así como para determinar el alta segura y para adaptar el nivel de atención que el paciente requiere, no sólo en el SUH, sino también a nivel de atención de emergencia primaria o extrahospitalaria.
Use of digoxin in the emergency department to treat patients with acute heart failure and its impact on short-term outcomes
Authors: Martín Mojarro Enrique , Gil Víctor , Llorens Pere , Álvarez Jesús , Flores Quesada Silvia , Troiano Ungerer Osvaldo J , Alquézar-Arbé Aitor , Jacob Javier , Herrero-Puente Pablo , Espinosa Begoña , Sánchez Carolina , Llauger Lluis , Tost Josep , Serrano Leticia , Dávila Aitor , Torres Garate Raquel , López-Grima María Luisa , Lucas-Imbernón Francisco Javier , Alonso Héctor , Pagán Fran , Garrido José Manue , Miró Òscar
Published: May 2024

Objetivos. Analizar los factores relacionados con el uso de digoxina en urgencias en pacientes con insuficiencia cardiaca aguda (ICA) y el impacto pronóstico a corto plazo. Método. Se incluyeron pacientes diagnosticados de ICA en 45 servicios de urgencias españoles sin tratamiento crónico con digoxina, los cuales se dividieron según recibiesen digoxina endovenosa en urgencias o no. Se recogieron 51 variables relativas al paciente o al episodio de descompensación y se investigó el perfil del paciente tratado con digoxina en urgencias. Como variables evolutivas se investigaron la necesidad de ingreso, la estancia en urgencias prolongada (> 24 horas) en dados de alta y la hospitalización prolongada (> 7 días) en ingresados, y la mortalidad intrahospitalaria y a 30 días por cualquier causa. Se analizó si el tratamiento con digoxina se asoció a diferencias evolutivas, de forma cruda y ajustada a las características del paciente y el episodio de ICA. Resultados. Se analizaron 15.549 pacientes (mediana = 83 años, mujeres = 55%), de los que 1.430 (9,2%) fueron tratados con digoxina. La digoxina se utilizó más en mujeres, pacientes jóvenes, en mejor clase funcional de la New York Heart Association (NYHA), pero con descompensaciones más graves y, sobre todo, cuando existía una fibrilación auricular (FA) con respuesta ventricular rápida como desencadenante. Se hospitalizó el 75,4% de pacientes (más frecuente en tratados con digoxina; 81,6% vs 74,8%, p < 0,001), tuvo estancia prolongada en urgencias el 38,3% (52,9% vs 37,2%, p < 0,001), hospitalización prolongada el 48,1% (49,3% vs 47,9%, p = 0,385), mortalidad intrahospitalaria el 7,2% (6,9% vs 7,2%, p = 0,712) y a 30 días el 9,7% (9,3% vs 9,7%, p = 0,625). El modelo ajustado mostró que el uso de digoxina en urgencias sólo se asoció con estancia prolongada en urgencias (OR = 1,883, IC 95% = 1,359-2,608), pero no con la necesidad de ingreso, hospitalización prolongada o mortalidad. Conclusiones. La digoxina continúa utilizándose en uno de cada 10 pacientes con ICA atendidos en urgencias que no utilizaban este fármaco de manera habitual. Su uso se relaciona con un paciente cuya ICA ha sido descompensada por una FA con respuesta ventricular rápida, más joven y más frecuentemente mujer, en mejor clase funcional de la NYHA basal y con una descompensación posiblemente más grave. El uso de digoxina conlleva una estancia en urgencias más prolongada, pero su uso es seguro, pues no se asocia a la necesidad de ingreso, hospitalización prolongada o mortalidad a corto plazo
O papel estratégico da holding no planejamento sucessório: mitigando os desafios da invalidade e garantindo a continuidade empresarial
Authors: Gonçalves Brunna Silva , Santos Guilherme Augusto Martins
Published: May 2024

A holding tem se tornado uma importante ferramenta para quem deseja planejar a sucessão de um patrimônio ou de empresas. Este artigo, visa, além de observar o processo de criação de uma holding familiar ou patrimonial como ferramenta principal no planejamento sucessório, analisando suas vantagens tributárias e redução de conflitos e proteção dos bens, também abordará quais as causas podem invalidar os efeitos deste tipo de empresa. O mecanismo holding traz ainda como finalidade maior, dirimir os impactos de uma sucessão não planejada que carrega consigo conflitos familiares, cargas tributárias elevadas e morosidade na efetivação, qual seja o testamento. A holding como ferramenta no planejamento sucessório tem demonstrado eficiência no seu objetivo principal, isso quando, através de profissionais qualificados, é feita de forma bem estruturada, analisando cada caso individualmente e traçando os objetivos a serem alcançados por aqueles que planejam. Por fim, observamos que detentores de bens e empresas têm se valido deste meio para fins fraudulentos, o que pode deixar a validação das holdings com caráter fragilizado, não restando outra consequência qual seja, a invalidação de seus efeitos. Neste estudo foi utilizado como metodologia, a pesquisa bibliográfica e documental, analisando artigos acadêmicos, jurisprudências, doutrinas, e os textos legais do ordenamento jurídico brasileiro. De modo geral, este artigo explana sobre o planejamento sucessório, a holding como ferramenta neste processo e as causas que podem invalidar a sua criação. Não obstante à importância deste mecanismo, que tem se tornado uma ferramenta relevante no meio empresarial e familiar, o trabalho também aponta os possíveis problemas inerentes à esta modalidade utilizada no planejamento sucessório, tais como fraude contra credores e a fraude à execução, e busca responder em que situações o uso dessa ferramenta pode ser considerado ilícito, levando ao reconhecimento de sua total invalidade quando esta tem a sua finalidade desviada.
Divergências entre as decisões do TJTO e STF: uma análise acerca da quantidade de drogas para fins de tráfico e para uso pessoal com base no voto do ministro Alexandre de Moraes
Authors: Rocha Rafaela Nascimento , Oliveira Bruno Vinícius Nascimento
Published: May 2024

As divergentes decisões proferidas pelo Tribunal de Justiça do Tocantins (TJ-TO) e o Supremo Tribunal Federal (STF) no que refere à quantidade de drogas para fins de tráfico e uso pessoal constitui tema de extrema relevância no atual cenário jurídico brasileiro. Isso porque, as várias interpretações decorrem da falta de parâmetros claros e objetivos em relação a quantidades para fins de tráfico e uso pessoal, o que tem acarretado diferentes entendimentos nos tribunais para indivíduos em situações semelhantes. Aspirando um entendimento mais específico acerca do tema, utilizou-se na pesquisa o método dedutivo e qualitativo, com o fim mapear casos específicos, bem como analisar os argumentos apontados pelo Ministro Alexandre de Moraes em seu voto proferido no STF acerca da quantidade para fins de tráfico e uso pessoal e os fundamentos utilizados pelo TJ-TO para proferir suas decisões. Diante do estudo empreendido, conclui-se que há uma tendência do Supremo Tribunal Federal em desclassificar a conduta da prática do tráfico de drogas para uso pessoal, sobretudo quando se trata de quantidades ínfimas. Esta inclinação, está fundamentada nos argumentos do Ministro Alexandre de Moraes, que considera não apenas a pequena quantidade apreendida, mas também outros elementos que caracterizam o tráfico. No entanto, no TJ- TO, observa-se uma gama de abordagens em relação à interpretação da quantidade de drogas, que por vezes é pautada nos argumentos levantados pelo Ministro Alexandre de Moraes e por vezes é desconsiderada, indicando que, apesar da importância das diretrizes estabelecidas pelo STF, a interpretação e a aplicação da legislação antidrogas na seara estadual são influenciadas por diversos fatores.
O planejamento tributário na utilização de holdings rurais: eficiência fiscal e limites legais
Authors: Rempel Guilherme José , Luz Crislene Divina dos Santos
Published: May 2024

O presente artigo objetiva asseverar que o holding rural que está inserido no campo do direito empresarial e tributário, possa vir a beneficiar com vantagens e benefícios proporcionais ao utilizar a holding, onde os limites definidos garantem a legitimidade desta estrutura de sociedade que está e são utilizadas no planejamento tributário rural. Em busca da eficiência fiscal dentro da legalidade da lei por meio da elisão fiscal, amortizar a carga tributária. A Holding Rural é uma estrutura jurídica que pode é criada para gerir o patrimônio do produtor rural e seus negócios, com a estrutura da Holding que é amplamente usada fins de gestão sucessória e tributária, o que releva e proporciona vários benefícios aos produtores rurais como a otimização da gestão. Neste mesmo sentido a holding do agronegócio tem como finalidade o patrimonio familiar rural, utilizando a pessoa jurídica. A principal função desse responsável jurídico é realizar a gestão da atividade rural dessa família de forma ampla, principalmente com relação ao seu patrimônio. Assim temos a o patrimonial que é o objetivo principal da holding na gestão do patrimônio e investimentos, a holding familiar tem como objetivo a gestão e a continuidade dos negócios da família. Portando este artigo direcione a identificar as finalidades da constituição da holding rural em buscas da eficiência fiscal dentro dos limites legais visando seus benefícios.
Desamparo imaterial dos ascendentes como possível causa de exclusão sucessória
Authors: Silva Rhafaella Cleisma Costa , Santos Guilherme Augusto Martins
Published: May 2024

O presente artigo aborda a temática do desamparo imaterial dos ascendentes como causa de exclusão sucessória, uma vez que, tradicionalmente, a legislação tem priorizado critérios patrimoniais para determinar a sucessão hereditária.  Assim, a problemática surge da ausência de uma previsão legal explícita para o tema em questão, levantando a seguinte indagação: quais instrumentos jurídicos são capazes de reconhecer e interpretar o desamparo imaterial, particularmente o abandono afetivo dos descendentes em relação aos ascendentes, como uma possível causa de deserdação? A pesquisa se justifica pela necessidade de compreender os limites e possibilidades do Direito frente ao fenômeno social crescente do desamparo imaterial dos ascendentes. Através da análise jurisprudencial e doutrinária, busca-se identificar os instrumentos legais que permitam a interpretação dessa problemática no âmbito da exclusão sucessória. A metodologia inclui a revisão de literatura especializada, análise de casos jurisprudenciais relevantes e reflexão sobre os princípios fundamentais do Direito de Família e Sucessório. Ao integrar esses elementos, o artigo visa contribuir para uma compreensão mais abrangente e sensível das relações familiares e sucessórias, promovendo uma abordagem mais inclusiva e justa no contexto do Direito brasileiro.
Tecnologia, Educação e Ensino Remoto
Authors: Souza Nelly Mary Oliveira de
Published: May 2024

A sociedade global, antes da pandemia do Covid – 19, imaginava que as tecnologias estariam à serviço da educação, mas sempre com delimitações e regulações de uso a fim de ser um meio adicional, mas não a essência das práticas educativas. Contudo, com o isolamento social, esse pensamento mais comedido foi ressignificado, tendo em vista que as TIC passaram ser, de algum modo, a própria educação por um longo período. Dessa maneira, este estudo de natureza bibliográfica pretende examinar a importância das TIC no contexto educativo do ensino remoto a fim de se possibilitar reflexões sobre limites e desafios. Com isso, por meio de análises pautadas no conteúdo, verificou-se que uma porta foi aberta e parece que não será mais fechada. As TIC compõem a educação de modo basilar e precisam adentrar cada vez mais os espaços sistemáticos de ensino, contudo sem abrir mão do contato pessoal e das relações existentes entre escola x professo x aluno.
CAMINHOS DA EDUCAÇÃO INCLUSIVA: O PAPEL TRANSFORMADOR DAS POLÍTICAS PÚBLICAS NO COMBATE DAS DISPARIDADES EDUCACIONAIS NAS COMUNIDADES QUILOMBOLAS
Authors: Santos Maria do Socorro Pereira dos , Ferreira Juvan da Cunha
Published: May 2024

Este resumo aborda estratégias educacionais voltadas para comunidades quilombolas, ancoradas em teorias de Paulo Freire, Amartya Sen, Ivan Illich e Vygotsky, entre outros. Destaca-se a premente necessidade de uma educação inclusiva, que assegure acesso universal, infraestrutura adequada e ambientes pedagógicos sensíveis à diversidade. Além disso, enfatiza- se a importância de integrar a cultura quilombola nos currículos escolares e de adotar medidas antirracistas para fomentar uma educação mais justa e igualitária. O investimento na formação docente é considerado crucial, juntamente com o estímulo à participação ativa das famílias e a implementação de políticas de permanência escolar. Essas medidas visam garantir que os alunos permaneçam na escola e concluam seus estudos de forma satisfatória. O texto destaca também a importância da avaliação contínua e da adaptação das políticas educacionais para atender às demandas em constante evolução dessas comunidades. Essa abordagem dinâmica busca promover um futuro educacional mais equitativo e justo, que reconheça e celebre a diversidade cultural e combata efetivamente o racismo estrutural. Ao adotar essas estratégias, busca-se não apenas garantir o acesso à educação, mas também empoderar as comunidades quilombolas, fortalecendo sua identidade cultural e proporcionando oportunidades para um desenvolvimento integral e autônomo.
APLICAÇÕES E IMPLICAÇÕES DA INTELIGÊNCIA ARTIFICIAL NA OTIMIZAÇÃO DE FARMACOTERAPIAS E PROCESSOS FARMACÊUTICOS
Authors: Soares Gabriela Silva , Santos Yasmim Cavalcanti Ribeiro dos , Pontes Neto João Gomes
Published: May 2024

Este estudo tem como objetivo é salientar a crescente importância da inteligência artificial (IA) no âmbito farmacêutico e de saúde, destacando sua capacidade de impulsionar transformações significativas em diversas esferas, abrangendo desde a pesquisa e fabricação de medicamentos até o diagnóstico e o envolvimento com os pacientes. Ademais, pretende-se explorar as considerações éticas e os obstáculos relacionados à integração da IA na indústria farmacêutica, enquanto ressalta os benefícios em potencial dessa tecnologia, como a melhoria dos procedimentos e a adaptação da terapia medicamentosa. Além disso, a IA tem sido aplicada no varejo farmacêutico para otimizar a gestão de inventário e antecipar as necessidades dos pacientes. No entanto, sua implementação enfrenta desafios, como a falta de estudos abrangentes sobre sua eficácia e a dificuldade de acesso a algoritmos atualizados. Esta pesquisa revisa a literatura sobre o emprego da inteligência artificial em farmacoterapias e processos farmacêuticos nos últimos cinco anos. Utilizando abordagem qualitativa, foram pesquisados artigos nas plataformas PubMed e BVS, com descritores específicos como Artificial Intelligence, Pharmaceutical, Chatbot in Pharmacy e Hospital Pharmacy. Após a exclusão de artigos fora do escopo temático, foram selecionadas 10 publicações relevantes.
Los predictores de la violencia en Ecuador: una visión integrada sobre sus factores criminógenos entre 2011 y 2022
Authors: Cruz Marte Israel , Sabando Ordóñez Aimee
Published: May 2024

El preente artículo sistematiza una visión integrada desde la criminología local sobre los factores criminógenos que explican el fenómeno de la violencia a partir del 2011 y el extraordinario repunte que inició el 2019 en Ecuador. Usa la Exégesis documental a partir de análisis criminológicos con base empírica en Ecuador y países con variables económico-criminológicas similares. Como resultados se percibe la presencia de cuatro análisis predictores criminógenos desde el análisis estructural hasta el análisis etnográfico y situacional. Éstos son: El quiebre de la movilidad social vertical positiva, la ilusión de riqueza, la ausencia de la figura paterna (problemas con la imagen de la masculinidad proveedora) y, finalmente, la relación entre el adolescente microtraficante y el impacto de la promulgación de la tabla de umbrales de consumo. Se construye el nuevo cuerpo teórico explicativo, basado en los efectos del cese de la riqueza súbita en el sistema de parentescos y la interpretación en éste de las oportunidades delictivas desde microtráfico hacia el narcotráfico.
An Unaccepted Official Quora: The Process of Guiding Online Youth Opinion by the Chinese Communist Youth League
Authors: Liu Yangge , Chen Yiying
Published: May 2024

Abstract: With reference to an online platform, Qingnian zhisheng, under the auspices of the Chinese Communist Youth League, this article focuses on the process by which the Chinese government guides the public opinions of young netizens. An authoritarian performance appraisal system was adopted to command and monitor the construction and promotion process of local agencies in a top-down and hierarchical approach. Under the increasingly strict appraisal requirements, the widening contradiction between state ideology and young netizens' demands has added a burden to grassroots bureaucrats' workload and eventually forced them to deviate from the original policy objective of online youth opinion guidance by fabricating performance appraisal data.
The Chinese Approach to Extraterritoriality
Authors: Tang Zheng
Published: May 2024

Abstract: China has abandoned its traditional territorially focused approach and has begun to assert extraterritorial jurisdiction by unilaterally regulating and intervening in activities occurring in the territory of other countries. China's view of extraterritoriality is derived from its strong economic power and evolves in the context of recent US–China tension. Its extraterritorial jurisdiction operates as a shield rather than as a sword; guided by pragmatism, however, China has retained the flexibility to utilise extraterritorial jurisdiction for other purposes. Extraterritoriality would serve the international community better if China regarded it as a rebalance of power between nations to form a rules-based international jurisdictional framework and not as an instrument to expand national power abroad.
Towards "All-round Cadres": Policy Priorities and Issue Diversity of Local Bureaucrats in China, 2005–19
Authors: Yang Zhusong , Yan Yang , Xu Haoxiang
Published: May 2024

Abstract: How do Chinese local political elites prioritise their attention in the one-party system? This study examines the issue diversity among China's local cadres by analysing the agendas of 707 local Party secretaries during their daily official activities from 2005 to 2019. Findings reveal that political and economic issues significantly dominate the secretaries' attention, overshadowing other niche topics. Yet after the 18th National Congress of the Communist Party of China (CPC) in 2012, there has been an increase in the secretaries' focus on Party affairs while there has been a decline in their focus on economic issues, leading to fragmented attention and disproportionate changes. These findings not only highlight the tension between the broader Party reforms and the actual responses of local officials, but also suggest the CPC's efforts to reshape the bureaucratic system by transforming local cadres into "all-rounders" capable of addressing diverse challenges while maintaining strong political leadership and loyalty.
Black Cube: The Stage for Performance in Singapore, 1995–96
Authors: Ho Chloe
Published: May 2024

Abstract: This article proposes the term 'black cube' to describe some forms of performance art in Singapore in the mid-1990s. While Claire Bishop had persuasively theorised the "gray zone" for theatrically-influenced performance art being presented in American art institutions, her gray zone does not describe the situation in Singapore. The gray zone presupposed a history of suspicion between the fields of visual art and theatre, a history that existed in New York through the writings of Michael Fried. This lineage does not properly exist in Singapore, as there has been a close relationship between visual art and theatre. This relationship deepened especially after 1994, when an incident with the Singapore state threw practitioners of both art and theatre toward a united front. This article will discuss events such as THE CUTTING EDGE [no, not the arts festival …] (29 February–30 March 1996), an experimental theatre festival by TheatreWorks (renamed T:>Works in 2020), which presented work that hovered on the precipice of art while determinedly declaring themselves as theatre. Jailani "Zai" Kuning's Growing Madness: The Day After (7–9 March 1996), Lee Wen's Hand-Made Tales (14–16 March 1996) were two works from this festival that demonstrate the character of the black cube. By discussing these case studies, the article expands upon Bishop's theorisation of performance space from a Singaporean lens. Unlike gray zone works, which were habituated to the white cube, black cube works continued to antagonise the categories of visual art and theatre through denying objective distance in the work.
/ Shi : A Signpost on the Blurry Map of Myanmar Art History
Authors: Htwe Diana Nway
Published: May 2024

Abstract: /Shi was a citywide satellite exhibition I co-curated in Yangon, Myanmar, held from 12 November 2022 to 12 January 2023. The exhibition was chiefly sponsored by the Goethe Institute of Yangon and comprised seven venues and over fifty artists. Art exhibitions are not rare in Myanmar and there have been other large-scale exhibitions prior to /Shi in the recent decade. However, the lack of critique and documentation on these activities in the Myanmar art world have rendered these art projects and cultural endeavours generationally unable to build upon their predecessors and always having to start from square one. This essay is a preventive measure against /Shi ’s foreboding fate of becoming another unreviewed model of exhibition-making in Myanmar. /Shi established once and for all that art and exhibitions that actively engage with the general public can still happen in postcoup Yangon. May /Shi ’s successes be built upon and failings understood .
Model Pengukuran Kinerja Rantai Pasok dengan Metode SCOR dan AHP di PT Sinar Sosro Medan
Authors: Sinaga Surya Rizki , Kodrat Kimberly F. , Harahap Bonar
Published: May 2024

Tujuan dari penelitian ini iyalah Mengidentifikasi faktor-faktor yang mempengaruhi kinerja rantai pasok di perusahaan, Menghitung tingkat kinerja rantai pasok perusahaan dengan menggunakan SCOR dan AHP, dari pengolahan data diketahui bahwa Peroses pemilihan indikator berdasarkan metode SCORE (Supply Chain Operational Reference ) yang memliki 5 indikator yaitu Plan (Proses Perencanaan), Source (Proses Pengadaan), Make (Proses Produksi), Deliver (Proses Pengiriman) dan Return (Proses Pengembalian), diketahui bahwa pada tabel 4.57 pada bagian pengumpulan dan pengolahan data diketahui terdapat 16 atribut terhadap kelima indikator tersebut. Rata-rata nilai indikator kinerja yang didapatkan berupa nilai 100 dengan keterangan Exellent dan nilai terenda yaitu sebesar 88,53 dengan keterangan Good pada bagian Row Material Planning Accuaracy, 83,33 Timely Drivery Performance By Supplier, 75 Delivey Item Accuracy By Supplier dan 87,5 Delivery Item Accuracy by The Company sesuai dengan indikator kinerja yang menandakan bahwa dari 5 atribut yang belum memenuhi standar indikator kinerja pada perusahaan adalah pada indikator Plan dengan atribut Row Material Planning Accuaracy ( Keakurasian perencanaan bahan baku) dan 2 atribut pada indikator source dan 1 atribut pada indikator Deliver pada  indikator sesuai Key Performance Indicator (KPI) yang di tetapkan oleh perusahaan yaitu 90 – 100.
Monitoring Environmental Factors Associated with Indoor Growth Chambers and Greenhouses for Cannabis Cultivation
Authors: Chiarakul Prayuth , Pinich Sarin , Sreshthaputra Atch
Published: May 2024

Greenhouse cultivation has no seasonal limitations and research is being conducted globally to assess control of environmental factors within greenhouses to optimize growing conditions. Attempts to improve the environmental factors in greenhouse cultivation include control of temperature, relative humidity, light intensity, carbon dioxide level, and air flow rate. Furthermore, indoor cultivation systems (growth chambers) have been developed and researched for comparison with greenhouse cultivation. In our study, comparative environmental data were collected in association with cannabis cultivation for a greenhouse and growth chamber, since commercial cannabis cultivation can include such methods. Accordingly, the data in this research were collected by choosing the same cannabis cultivars for both cultivation methods and by controlling the internal growing environments that affected cultivation. Data also were collected on the plant biochemical properties over the same time period and the collected data were analyzed using psychrometric charts. The findings of this research show that if the internal environment of the indoor cultivation method is well-regulated, better results in cannabidiol (CBD) extraction from blossoms can be achieved as compared to greenhouse cultivation, in which environmental regulation is less precise. Therefore, we conclude that if we can control the internal environment of greenhouse cultivation to be similar to the indoor cultivation method, the productivity of the two methods should be similar. The findings of this research can be used to develop greenhouse cultivation methods for other plants in order to improve future productivity and efficiency.
Idiopathic Calcinosis Cutis of the left great toe-A case report
Authors: Nidhi Choudhari , Vishwantha Meghashree , Vidhya Subramanian , Vedhachalam Ramamurthy
Published: May 2024

Calcinosis cutis, a rare benign disorder, involves systemic calcium deposition in soft tissues, often linked with autoimmune and renal disorders. Pathophysiology varies among its five main types: dystrophic, metastatic, idiopathic, iatrogenic, and calciphylaxis. Dystrophic calcification, the most common type, is associated with normal calcium and phosphorus levels and autoimmune diseases. Metastatic calcification, on the other hand, arises from abnormal serum calcium and phosphorus levels. Idiopathic calcification lacks underlying tissue damage or abnormal laboratory values. Iatrogenic calcification was triggered by calcium or phosphate-containing substances. Calciphylaxis involves vessel calcification and is linked to chronic renal failure and dialysis. A 19-year-old female presented with pain and swelling on her left great toe plantar aspect, diagnosed as unilateral idiopathic calcinosis cutis. A comprehensive diagnostic approach, including histopathological, radiological, and blood investigations, is crucial for effective management. The study aimed to highlight idiopathic cutaneous calcinosis, emphasizing its accurate diagnosis through clinical, pathological, and metabolic correlation. Surgical excision offers a complete cure for this rare condition, leading to an excellent prognosis.