bluuebunny/crossref_metadata_2025 huggingface dataset:
Challenges in Recruiting University Students for Web-Based Indicated Prevention of Depression and Anxiety: Results From a Randomized Controlled Trial (ICare Prevent)
Authors: Bolinski Felix , Kleiboer Annet , Neijenhuijs Koen , Karyotaki Eirini , Wiers Reinout , de Koning Lisa , Jacobi Corinna , Zarski Anna-Carlotta , Weisel Kiona K , Cuijpers Pim , Riper Heleen
Published: September 2022

Background

Depression and anxiety are common mental health conditions in college and university student populations. Offering transdiagnostic, web-based prevention programs such as ICare Prevent to those with subclinical complaints has the potential to reduce some barriers to receiving help (eg, availability of services, privacy considerations, and students’ desire for autonomy). However, uptake of these interventions is often low, and accounts of recruitment challenges are needed to complement available effectiveness research in student populations.

Objective

The aims of this study were to describe recruitment challenges together with effective recruitment strategies for ICare Prevent and provide basic information on the intervention’s effectiveness.

Methods

A 3-arm randomized controlled trial was conducted in a student sample with subclinical symptoms of depression and anxiety on the effectiveness of an individually guided (human support and feedback on exercises provided after each session, tailored to each participant) and automatically guided (computer-generated messages provided after each session, geared toward motivation) version of ICare Prevent, a web-based intervention with transdiagnostic components for the indicated prevention of depression and anxiety. The intervention was compared with care as usual. Descriptive statistics were used to outline recruitment challenges and effective web-based and offline strategies as well as students’ use of the intervention. A basic analysis of intervention effects was conducted using a Bayesian linear mixed model, with Bayes factors reported as the effect size.

Results

Direct recruitment through students’ email addresses via the central student administration was the most effective strategy. Data from 35 participants were analyzed (individually guided: n=14, 40%; automatically guided: n=8, 23%; care as usual: n=13, 37%). Use of the intervention was low, with an average of 3 out of 7 sessions (SD 2.9) completed. The analyses did not suggest any intervention effects other than anecdotal evidence (all Bayes factors10≤2.7).

Conclusions

This report adds to the existing literature on recruitment challenges specific to the student population. Testing the feasibility of recruitment measures and the greater involvement of the target population in their design, as well as shifting from direct to indirect prevention, can potentially help future studies in the field. In addition, this report demonstrates an alternative basic analytical strategy for underpowered randomized controlled trials.

Trial Registration

International Clinical Trials Registry Platform NTR6562; https://tinyurl.com/4rbexzrk

International Registered Report Identifier (IRRID)

RR2-10.1186/s13063-018-2477-y
Validity and Internal Consistency Assessment of a Tablet-Based Aphasia Assessment System "STELA" (Preprint)
Authors: Inamoto Yoko , Mukaino Masahiko , Imaeda Sayuri , Sawada Manami , Satoji Kumi , Nagai Ayako , Hirano Satoshi , Okazaki Hideto , Saitoh Eiichi , Sonoda Shigeru , Otaka Yohei
Published: September 2022

BACKGROUND

There is an extensive library of language tests with excellent psychometric properties; however, many of them take considerable time for administration possibly causing psychological stress in patients. The Short and Tailored Evaluation of Language Ability (STELA) is a simplified, tablet-based language ability assessment system developed to address this issue, with a reduced number of items and automated testing process.

OBJECTIVE

To test validity and internal consistency of STELA.

METHODS

Patients with aphasia diagnosed by the Japanese version of the Western Aphasia Battery (WAB) participated in this study. Concurrent validity of STELA was estimated to compare with the WAB, investigating the correlation between the total score of STELA and the WAB Aphasia Quotient (AQ). The correlation between subscales was also examined. The internal consistency of the STELA was tested using Cronbach’s α of each modality and item–total correlations.

RESULTS

STELA’s total score was strongly correlated with the WAB Aphasia Quotient (AQ; r=0.96, P<.001), supporting the former’s concurrent validity concerning the WAB, which is a gold-standard aphasia assessment. Strong correlations were also observed at the subscale level; STELA Auditory comprehension vs. WAB Auditory comprehension (r=.85, P<.001), STELA Repetition vs. WAB Repetition (.90, <.001), STELA Naming and sentence formation vs. WAB Naming and word finding (.89, <.001), and the sum of STELA Reading comprehension or Reading aloud vs. WAB reading (.90, <.001). Cronbach’s α coefficients obtained for each modality were Auditory comprehension .862, Reading comprehension .872, Naming and sentence formation .902, Repetition .787, and Reading aloud .892. Global Cronbach’s α was calculated as .961. The average of the values of item–total correlation to each subscale was .67[.16].

CONCLUSIONS

Our study provides positive evidence for the internal consistency and validity of the STELA tablet-based aphasia assessment system.
Digitally Delivered Interventions to Improve Nutrition Behaviors Among Resource-Poor and Ethnic Minority Groups With Type 2 Diabetes: Systematic Review (Preprint)
Authors: Karimi Nazgol , Opie Rachelle , Crawford David , O’Connell Stella , Ball Kylie
Published: September 2022

BACKGROUND

Resource-poor individuals, such as those with a low income, are disproportionately affected by diabetes and unhealthy eating patterns that contribute to poor disease self-management and prognosis. Digitally delivered interventions have the potential to address some of the barriers to healthy eating experienced by this group. However, little is known about their effectiveness in disadvantaged populations.

OBJECTIVE

This systematic review is conducted to assess the effectiveness of digitally delivered interventions in improving nutritional behaviors and nutrition‐related health outcomes among disadvantaged people with type 2 diabetes (T2D).

METHODS

MEDLINE complete, Global Health, Embase, CINAHL complete, Informit Health, IEEE Xplore, and Applied Science and Technology Source databases were searched for studies published between 1990 and 2022 on digitally delivered nutrition interventions for disadvantaged people with T2D. Two reviewers independently assessed the studies for eligibility and determined the study quality using the Cochrane Risk-of-Bias Assessment Tool. The Behavioral Change Technique Taxonomy V1 was used to identify behavior change techniques used in the design of interventions.

RESULTS

Of the 2434 identified records, 10 (0.4%), comprising 947 participants, met the eligibility criteria and were included in the review. A total of 2 digital platforms, web and messaging services (eg, SMS text messaging interventions or multimedia messaging service), were used to deliver interventions. Substantial improvements in dietary behaviors were reported in 5 (50%) of the 10 studies, representing improvements in healthier food choices or increases in dietary knowledge and skills or self-efficacy. Of the 10 studies, 7 (70%) examined changes in blood glucose levels, of which 4 (57%) out of 7 achieved significant decreases in hemoglobin A1C levels ranging from 0.3% to 1.8%. The most frequently identified behavior change techniques across all studies were instruction on how to perform the behavior, information about health consequences, and social support.

CONCLUSIONS

This review provided some support for the efficacy of digitally delivered interventions in improving healthy eating behaviors in disadvantaged people with T2D, an essential dietary prerequisite for changes in clinical metabolic parameters. Further research is needed into how disadvantaged people with T2D may benefit more from digital approaches and to identify the specific features of effective digital interventions for supporting healthy behaviors among disadvantaged populations.

CLINICALTRIAL

PROSPERO International Prospective Register of Systematic Reviews CRD42020149844; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=149844
Capturing the Dynamics of the Social Environment Through Experience Sampling Methods, Passive Sensing, and Egocentric Networks: Scoping Review (Preprint)
Authors: Langener Anna M , Stulp Gert , Kas Martien J , Bringmann Laura F
Published: September 2022

BACKGROUND

Social interactions are important for well-being, and therefore, researchers are increasingly attempting to capture people’s social environment. Many different disciplines have developed tools to measure the social environment, which can be highly variable over time. The experience sampling method (ESM) is often used in psychology to study the dynamics within a person and the social environment. In addition, passive sensing is often used to capture social behavior via sensors from smartphones or other wearable devices. Furthermore, sociologists use egocentric networks to track how social relationships are changing. Each of these methods is likely to tap into different but important parts of people’s social environment. Thus far, the development and implementation of these methods have occurred mostly separately from each other.

OBJECTIVE

Our aim was to synthesize the literature on how these methods are currently used to capture the changing social environment in relation to well-being and assess how to best combine these methods to study well-being.

METHODS

We conducted a scoping review according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.

RESULTS

We included 275 studies. In total, 3 important points follow from our review. First, each method captures a different but important part of the social environment at a different temporal resolution. Second, measures are rarely validated (>70% of ESM studies and 50% of passive sensing studies were not validated), which undermines the robustness of the conclusions drawn. Third, a combination of methods is currently lacking (only 15/275, 5.5% of the studies combined ESM and passive sensing, and no studies combined all 3 methods) but is essential in understanding well-being.

CONCLUSIONS

We highlight that the practice of using poorly validated measures hampers progress in understanding the relationship between the changing social environment and well-being. We conclude that different methods should be combined more often to reduce the participants’ burden and form a holistic perspective on the social environment.
Soft Skills Needed by Marketing Majors upon Graduation
Authors: M. Johnson Katryna
Published: September 2022

Are marketing students graduating with the skills business professionals demand? This paper will examine the soft skills needed by marketing majors upon graduation. A literature review was performed of 51 studies from recent years analyzing key skills mentioned in literature by marketing professionals. This study found that the most frequently mentioned softs skills included adaptability, analytical reasoning, collaborating with diverse individuals, communication (written and verbal), critical thinking, creativity, detail orientation, interpersonal skills, leadership, problem solving, professionalism, public speaking/presentation skills, resilience, teamwork and time management. This paper will discuss the major skills needed by marketing students and will make recommendations for future research on hard skills and digital marketing.
Prevalencia de la clasificación del ponticulus posticus en pacientes de nueve a 25 años en una población en Cuenca-Ecuador
Authors: Becerra-Moreira María Auxiliadora , Pacheco-Pesántez Diana Estefanía , Vidal-Dávila Tatiana Alexandra , Villavicencio-Caparó Ebingen , Cruz-Hervert Luis Pablo , Barzallo-Sardi Vinicio
Published: September 2022

Objetivo: Determinar la prevalencia del ponticulus posticus en radiografías digitales laterales de cráneo. Material y métodos: Se seleccionaron aleatoriamente radiografías digitales laterales de cráneo de la base de datos de un centro de radiología oral y maxilofacial de la ciudad de Cuenca, Ecuador, de pacientes entre nueve y 25 años entre 2013-2015. Se estimó la prevalencia del ponticulus posticus según la clasificación de Cederberg y Stubbs y se estratificó por sexo. Se realizó un análisis de regresión multivariante multinomial para comparar la asociación entre edad y sexo con la clase 2, 3 y 4 frente a la clase 1. Los datos se analizaron en el programa STATA V13.0. Resultados: Se analizaron 1,000 radiografías laterales de cráneo, la edad promedio fue de 15 (± 4.23) años y 57.60% (n = 424) eran mujeres. La prevalencia de clase 1 fue de 71.8% (IC 95% 68.92-74.51), clase 2 fue 16.5% (IC 95% 14.32-18.94), clase 3 fue 5.5% (IC 95% 4.24-7.10) y clase 4 fue 6.20% (IC del 95%: 4.86 a 7.88). Según el análisis multivariado, se identificó que los hombres tenían mayor posibilidad de tener una clase 2 o 3 que clase 1, mientras que los pacientes mayores eran clase 4 en comparación con clase 1. Conclusiones: Ponticulus posticus es una variante anatómica de alta prevalencia en la población estudiada. En la clasificación de Cederberg y Stubbs se observó mayor prevalencia de la clase 1 de ponticulus posticus. La calcificación se extiende a menos de la mitad de la arteria vertebral. Los hombres mostraron mayor prevalencia de clase 2. El aumento de la frecuencia de clase 4 se asoció con el aumento de la edad. La clase 1 de la misma clasificación no tenía importancia clínica, ya que no se observó calcificación de ningún tipo.
Cinco importantes ventajas del sistema Tip-Edge en ortodoncia fija
Authors: Medellín Fuentes Ricardo , Kesling Peter C
Published: September 2022

Hoy en día las diferentes alternativas para realizar un tratamiento de ortodoncia fija son variadas después de haber enseñado y tratado maloclusiones por 30 años con diferentes técnicas ortodóncicas tales como Begg, Edgewise, Alexander, MBT, incluyendo diferentes brackets de autoligado, entre otras. Considerando las ventajas que nos proporciona la técnica de Tip-Edge podría enumerar algunas de ellas como rapidez, comodidad tanto para el paciente como para el operador, la fácil y rápida apertura de la mordida así como el cierre de espacios de extracción, simétrico y asimétrico, la forma independiente de dar torque, entre otras más. Sin embargo, en el presente artículo se pone énfasis en cinco ventajas que marcan un precedente en la práctica clínica diaria y que pueden ser de utilidad para los clínicos acostumbrados a manejar cualquier otra técnica de ortodoncia fija.
Elongated Mental Spine with Two Lingual Foramina in the Mandible of A Kurdish Woman: A Case Report
Authors: Hagi Fadi , Yaseen Yaseen Sedeeq , Hassan Liqaa Jabir
Published: September 2022

The mental spines are bony prominences found in the lingual surface of anterior mandible, and usually they are arranged in two groups, superior pair and inferior pair. Mostly they are asymptomatic, but sometimes they may interfere with the prosthodontic treatment or with some surgeries. The lingual foramen can be found in different locations around the mental spines, and they are very important vital organ because they transmit nerves and arteries, which may cause a serious problem during some types of surgeries in this region such as implant placement. Here, we report a case of 55-year-old, Kurdish woman with elongated superior mental spine with bilaterally lingual foramina located distally to lower central incisors, that have been seen during a routine CBCT scan. The length of the spine was 6.4 mm, the height was 5.5 mm and the width was 1.9 mm. So, any dentist wants to perform any type of surgery in sublingual and submental regions should be careful of such anatomical variations.
A study of relationship between SARS-CoV-2 antibodies levels and host factors among general population in Zakho City, Iraq
Authors: R Hussein Nawfal , A Naqid Ibrahim , A Jamal Shakir , Balatay Amer , Ibrahim Nashwan , H Musa Dildar , S M. Saleem Zana
Published: September 2022

Objectives: The aim of this cross-sectional study is to evaluate the seroprevalence of total antibodies to SARS-CoV-2 and associated risk factors in Zakho City, Kurdistan Region of Iraq.

Methods: This cross-sectional study was performed at Zako City, Northern, Iraq. Blood samples were collected from different districts of Zakho city between January and March 2021. Immunoassays were performed to detect the total antibodies against SARS-CoV-2, and the associations between several variables were investigated.

Results: A total of 315 participants were agreed and enrolled in the study. The average age of the participants was 32.87±13.25 years.  Among the participants, 214/315 (67.93%) were found to have antibodies against SARS-CoV-2. Among those who had positive antibodies, 169/214 (78.97%) were asymptomatic and 45/214 (21.03%) had a history of COVID-19 related symptoms. The most common symptom was fever (95.56%), followed by loss of smell (84.44%) and myalgia (80.0%). We found that antibody levels significantly associated with age (P=0.021). The presence of symptoms was significantly higher among subjects with a history of comorbidity diseases (P=0.038), and older people (P = 0.015). A significant association was found between antibody levels and the marital status (P=0.014), chronic diseases (P=0.001), presence (P=0.015) and duration of symptoms (P=0.028).

Conclusion: A significant association between antibody levels to SARS-CoV-2 and age, chronic diseases, presence and duration of symptoms were found in this study. Seroprevalence studies of antibodies to SARS-CoV-2 among general population are of utmost importance to develop infection prevention programs in our society.
Akdeniz Ülkelerinin Deniz Sağlığı Performanslarının Analizi: CRITIC Tabanlı MARCOS Yöntemi İle Bir Uygulama
Authors: Altıntaş Furkan Fahri
Published: September 2022

Akdeniz’e kıyısı olan ülkelerin deniz sağlığı konusundaki faaliyetlerinin Akdeniz’in yarı kapalı havzası olması sebebiyle diğer Akdeniz ülkelerinin deniz sağlığı performanslarını etkileyebildiği için Akdeniz ülkelerinin deniz sağlığı performanslarının analizi büyük önem arz etmektedir. Bu kapsamda araştırmada, 19 Akdeniz ülkesinin 2021 yılı için Okyanus Sağlığı Endeksi (Ocean Health Index-OHI) bileşenlerine ait değerler üzerinden söz konusu ülkelerin deniz sağlığı performansları CRITIC tabanlı MARCOS çok kriterli karar verme (ÇKKV) yöntemi ile ölçülmüştür. Bulgulara göre, CTIRIC yöntemi kapsamında ülkelere göre en önemli deniz sağlığı bileşeninin ‘‘Geçim Kaynakları ve Ekonomiler’’ olduğu tespit edilmiştir. Ayrıca bulgular kapsamında CRITIC tabanlı MARCOS yöntemine göre deniz sağlığı performansı en fazla olan ilk üç ülkenin sırasıyla Slovenya, İspanya ve Fransa, en az olan ilk üç ülkenin ise Suriye, İsrail ve Libya olduğu gözlenmiştir. Araştırmada ayrıca CRITIC tabanlı MARCOS yöntemine göre ülkelerin ortalama deniz sağlığı performansı ölçülmüş ve ortalamadan düşük değerde olan ülkelerin Akdeniz’in deniz sağlığının daha iyi olması için deniz sağlığı performanslarını artırmaları gerektiği sonucuna ulaşılmıştır. Yöntem açısından ise OHI kapsamında ülkelerin deniz sağlığı performansları başta CRITIC tabanlı MARCOS yöntemi olmak üzere CRITIC tabanlı ARAS, EDAS, COPRAS ve TOPSIS ÇKKV yöntemleri ile ölçülebileceği değerlendirilmiştir.
Variables asociadas a la intención de compra de yogur con etiqueta ecológica: un estudio descriptivo
Authors: Herrera-González Daniel Antonio
Published: September 2022

El objetivo de este estudio fue analizar la asociación de la intención de compra para el producto yogur con etiqueta ecológica y variables como emociones y sentimientos, mensaje ambiental en el empaque, conciencia y conocimiento del comprador, frente a la asociación ambiental en la compra, el involucramiento y los beneficios del producto en relación con la intención de compra. El enfoque de la investigación fue tipo cuantitativo con un alcance descriptivo. Para ello se recolectaron 554 casos aplicados a consumidores que compran un yogur en Bogotá-Colombia por medio de una encuesta estructurada de forma PAPI (Paper and Pencil Interview o entrevista asistida con cuestionario en papel). El principal hallazgo de la presente investigación es que la etiqueta ecológica no tiene una relación significativa con la intención de compra del producto yogurt, demostrando estadísticamente que la etiqueta ecológica no influencia la intención de compra del consumidor. El estudio demuestra que las empresas deben focalizarse en generar más educación y campañas comunicativas para crear conciencia, conocimiento e involucramiento en la compra y beneficios del producto para que la etiqueta ecológica realmente funcione como un atributo que incremente la intención de compra.
La intención emprendedora de los científicos universitarios en Colombia
Authors: Tarapuez-Chamorro Edwin , Guzmán-Díaz Beatriz Elena , Parra-Hernández Ramiro
Published: September 2022

El objetivo de este trabajo fue establecer las principales asociaciones de las normas sociales, actitudes y variables de control de comportamiento con la intención emprendedora (IE) de los científicos universitarios en Colombia e identificar cuáles son los factores clave que la determinan. Esta investigación fue descriptiva y correlacional, con enfoque cuantitativo; el diseño fue no experimental y transversal; se utilizaron dos métodos para el análisis de los datos: correspondencias múltiples y regresión logística. Se tomó una muestra aleatoria estratificada de 636 científicos de la base de datos del Ministerio de Ciencia, Tecnología e Innovación (TIC) de Colombia, en las áreas de ciencias, tecnología, ingeniería y matemáticas. Del total de encuestas de la muestra, 597 fueron válidas. Los resultados indicaron que los científicos universitarios con mayores niveles de formación (doctorado y postdoctorado) estuvieron asociados con la comercialización de los resultados de sus investigaciones y que las normas sociales mostraron una mayor determinación de la IE. Se concluye que los científicos universitarios con las modalidades más avanzadas de IE, es decir, quienes tienen o tuvieron empresa, que estaban creándola o que estuvieron decididos a hacerlo, se relacionan en general con una visión positiva de las normas sociales y las actitudes estudiadas.
Mirada caleidoscópica a los cuentos “una felicidad repulsiva” y “una madre protectora”
Authors: Valencia Gómez María Rosa
Published: September 2022

Desde tiempo antiguos, el hombre a través del aforismo griego “Conócete a ti mismo” ha iniciado una búsqueda que parece no tener fin, desde este precepto la sociedad es una variante para determinar la falta de: esencia, libertar, empatía y demás elementos que por medio de la literatura son explorados. La humanidad desde su génesis no ha dejado de “relatar” ese verbo tan corto pero conciso, devela la compleja necesidad de expresar a través de las letras experiencias vividas. 

Es este sentido, se trae a colación dos cuentos que hacen parte del libro Una felicidad repulsiva, escrito por el Argentino Guillermo Martínez, uno de ellos alude al título de la obra y es la pieza inicial, una historia con matices variados los cuales sumergen al lector en un juego metaficcional, donde la felicidad es el eje temático y sus personajes giran alrededor de esa sensación, que todo sujeto desea obtener. De esta manera, Martínez abre la puerta a secretos familiares, pugnas clasistas y grietas emocionales, que hacen parte de la naturaleza del hombre.
Así mismo, se retoma la historia “Una madre protectora”, con el que se da por concluido el libro, donde el personaje principal traspasa los límites de la maternidad desde un interés desmedido por el hijo, fascinación que emerge en el vientre y continua de manera exagerada con el nacimiento y posteriores etapas de desarrollo. Se puede juzgar las actitudes de ella o más bien compaginar con el amor enfermizo, de esta forma la mujer encarnar el prototipo de madre perfecta que desea hacer lo imaginable para que su hijo este a salvo y aunque son perturbadoras las acciones que realiza, es probable que una madre como dice el título “protectora” justifiqué el actuar del personaje.
El lector entonces, lograr sentirse identificado con el simbolismo de la maternidad en todo su esplendor, esa que ama, cuida, protege, alimenta, vela, enseña y sobre todo no se equivoca... Al parecer una maternidad idealizada, casi sublime. En este orden de ideas, los dos cuentos son un entramado de historias que ejemplifican la crudeza del sujeto ante la vida y sus atormentadas realidades.
Ruta de innovación social en un grupo de estudiantes del programa de administración de empresas de la Corporación Universitaria Minuto de Dios - UNIMINUTO en el municipio de Ibagué
Authors: Andrade Restrepo Lina María , Rico Otalora Byron Armando , Gómez Bonilla Laura Rita
Published: September 2022

El presente artículo muestra la implementación de la ruta de la innovación social, metodología creada por el parque científico de innovación social PCIS, ruta que, aborda problemáticas, que intentan solucionarse, mediante la participación de diferentes actores y recursos. El objetivo principal de la investigación fue desarrollar e implementar la metodología para la ejecución de la ruta de innovación social en el curso análisis y diagnóstico organizacional del programa de Administración de Empresas (AEMD) de la Vicerrectoría del Tolima y Magdaleno Medio (VTMM) Corporación Universitaria Minuto de Dios – Uniminuto en el municipio de Ibagué. La metodología utilizada en la investigación fue cualitativa, se recurrió también a el método de investigación acción contando con la participación del docente que orienta el curso y los estudiantes. Como resultados principales se encontró que los estudiantes pudieron aplicar los conocimientos vistos en el curso en un entorno real.  Asimismo, ellos lograron generar mayores habilidades organizativas, resultado de la interacción con los tenderos y el funcionamiento de sus tiendas. Por otro lado, Los tenderos de la comuna 6 evidenciaron algunas falencias en el desarrollo de las actividades que realizaban en sus tiendas.
Análisis de la implementación de una Política Pública Educativa utilizando la herramienta Atlas Ti
Authors: Velandia Moncada Nancy Yamile
Published: September 2022

Una política pública se genera de la necesidad de modificar una situación problema identificada en una sociedad, por medio de acciones tomadas desde un ente gubernamental (Deubel, 2002) en Colombia en el año 2015 se planteó la Política de Día de la Excelencia como respuesta a la necesidad de mejorar los resultados académicos y alcanzar el objetivo de otra política que se propuso en este mismo año “Colombia la mejor educada en el 2025”. La investigación a nivel general busca identificar aspectos relevantes en la implementación de la política “Día E” mediante el análisis de los aspectos institucionales que convergen en el mejoramiento de la calidad educativa por medio de un estudio de caso en las instituciones educativas públicas de Zipaquirá, Colombia. El propósito del artículo es ofrecer una propuesta para el análisis de un documento institucional que se denomina Sistema Institucional de Evaluación de los Estudiantes SIEE (Ministerio de Educación Nacional de Colombia, 2009), que hace parte de las acciones que se desarrollan dentro de los centros educativos y que son objeto de evaluación en el Día de la Excelencia, se presenta entonces como recurso metodológico el programa de Atlas Ti para el análisis documental. En cuanto a la metodología se tiene una primera etapa que consistió en la recopilación del documento SIEE de cada uno de los 10 centros educativos del municipio de Zipaquirá, luego el investigador asumió la responsabilidad de realizar una codificación de acuerdo con un sistema categorial propuesto y previamente validado, posteriormente se hace una interpretación semántica del texto y por último se presentan unos resultados y conclusiones corroborados con la fundamentación teórica. En cuanto a los resultados más relevantes se identificaron los conceptos claves que deben ser presentados en los documentos SIEE, para que tengan una validez y sean realmente los derroteros que permitan mejorar la calidad eductaiva desde los actores institucionales, se determinan también acciones de mejora que se deben implementar desde los documentos y se concluyen cuáles son las categorías que se deben trabajar desde los SIEE para la implementación de las propuestas del Día E.
Vaginal changes after ovariectomy in ewes -- a large animal model for Genitourinary Syndrome of Menopause
Authors: Vodegel Eva , Guler Zeliha , Ras Lamees , Mackova Katerina , Groeneveld Anne , Bezuidenhout Deon , Deprest Jan , Jeffrey Stephen , Roovers Jan-Paul
Published: September 2022

Objective: To evaluate the effect of iatrogenic menopause on the
physiology of the vagina of the ewe, and to evaluate if vaginal changes
in ewes can be translated to women with the genitourinary syndrome of
menopause (GSM). Design: Animal study, randomised design for ovariectomy
or control, blinded for allocation and outcome assessment. Setting:
University of Cape Town, South Africa. Population or Sample: Twenty-five
Dohne Merino ewes. Methods: Iatrogenic menopause was induced in 20
animals by bilateral ovariectomy. Five animals served as a control group
(no intervention). Differences between groups were determined by linear
regression analyses (adjusted for baseline scores) at 5 months after
ovariectomy. Main Outcome Measures: Vaginal epithelial thickness, pH,
vaginal maturation value, vaginal maturation index, epithelial glycogen
accumulation, content of elastin fibres, collagen, and vascularity.
Results: Ovariectomised ewes showed epithelial thinning of the vaginal
wall from 146 µm to 47 µm (mean, p <0.001 ). In addition,
epithelial glycogen accumulation (43%) and the vascularity (23%) of
the vaginal wall significantly decreased as compared to the control
group. No differences were found for vaginal pH, vaginal cytology
outcomes, elastin fibres and collagen content. Conclusions: This study
established the ewe as a suitable large animal model for GSM.
Furthermore, the similar relevant outcomes in humans and ewes hold great
value for future translational research for the evaluation and
optimisation of different treatment modalities for GSM. Funding: None.
Keywords: Atrophy, ewe, genitourinary syndrome of menopause, model,
ovariectomy.
A Higher-Order New Approach Numerical Method for Singularly Perturbed Parabolic Reaction-Diffusion Problems
Authors: Gelu Fasika Wondimu , Kebede Guta Demisu , Birlie Birhanu Sisay , Dangaro Mesfin Bogale
Published: September 2022

In this study, a higher-order new approach numerical method for solving
singularly perturbed parabolic reaction-diffusion problems has
presented. To discretize time variable, we used the Crank-Nicolson
method on uniform mesh and space variable, we used hybrid numerical
method comprising a cubic spline tension method in the inner regions and
a central difference method in the outer region on Shishkin mesh. The
proposed method is proved to be uniformly convergent irrespective of the
perturbation parameter. Three numerical examples are computed to
validate the theoretical findings.
Impact of intra-host immune adaptations on the evolution of SARS-CoV-2 S protein among individuals with SARS-CoV-2 infections in South Africa, 2020 to 2022
Authors: Subramoney Kathleen , Mtileni Nkhensani , Davis Ashlyn , Giandhari Jennifer , Naidoo Yeshnee , Ramphal Yajna , Pillay Sureshnee , Ramphal Upasana , Tegally Houriiyah , Wilkinson Eduan , Simane Andiswa , Reddy Bhaveshan , Mashishi Bonolo , Mbenenge Nonhlanhla , Oliveira Tulio de , Fielding Burtram , Treurnicht Florette
Published: September 2022

Background Intra-host diversity studies are used to characterise
mutational heterogeneity of SARS-CoV-2 infections to understand the
impact of virus-host adaptations. This study investigated the frequency
and diversity of the spike (S) protein mutations within SARS-CoV-2
infected South African individuals. Methods Single nucleotide
polymorphism (SNP) assays and whole genome sequencing were performed on
SARS-CoV-2 positive samples. Allele frequency (AF) was determined using
TaqMan Genotyper software for SNP analysis and galaxy.eu for analysis of
FASTQ reads. Results The SNP assays identified 5.3% (50/948) Delta
cases with heterogeneity at delY144 (4%; 2/50), E484Q (6%; 3/50),
N501Y (2%; 1/50) and P681H (88%; 44/50). Sequencing identified 9%
(210/2381) cases with Beta, Delta, Omicron BA.1, BA.2.15, and BA.4
lineages with heterogeneity in the S protein. Heterogeneity was
primarily identified at positions 19 (1.4%) with T19IR (AF 0.2-0.7),
371 (92.3%) with S371FP (AF 0.1-1.0), and 484 (1.9%) with E484AK
(0.2-0.7), E484AQ (AF 0.4-0.5) and E484KQ (AF 0.1-0.4). Conclusion
Mutations at heterozygous amino acid positions 19, 371 and 484 reduce
recognition of neutralising antibodies, however the impact of the
multiple substitutions at the same position is unknown. Therefore, we
hypothesise that intra-host SARS-CoV-2 quasispecies with heterogeneity
in the S protein facilitate competitive advantage of variants that can
completely/partially evade host’s natural and vaccine-induced immune
responses.
A Transformer-Convolutional Neural Network Based Framework for Predicting Ionic Liquid Properties
Authors: Chen Guzhong , Song Zhen , Qi Zhiwen
Published: September 2022

Of central importance to evaluate the suitability of ionic liquids (ILs)
for a process is the accurate estimation of IL properties related to
target performances. In this work, a versatile deep learning method for
predicting IL properties is developed. Molecular fingerprints are
derived from the encoder state of a Transformer model pre-trained on the
PubChem database, which allows transfer learning from large-scale
unlabeled data and significantly improves generalization performance for
developing models with small datasets. Employing the pre-trained
molecular fingerprints, convolutional neural network (CNN) models for IL
properties prediction are trained and tested on 11 databases. The
obtained Transformer-CNN models present superior performance to
state-of-the-art models in all cases and enable property prediction of
millions of ILs shortly. The application of the proposed models is
exemplified by searching CO2 absorbent from a huge database of 8,333,096
synthetically feasible ILs, which is by far the most high-throughput IL
screening in literature.
Effect of Preoperative Use of Nonsteroidal Anti-inflammatory Drugs on Dental Sensitivity Induced by Dental Bleaching in the Dental Office: A Systematic Review and Meta-analysis
Authors: da Silva ARJ , Muniz RPD , de Assis CPP , da Siva EP , de Albuquerque MS , Lago MCA , Braz R
Published: September 2022

Aim

This systematic review and meta-analysis evaluated the effect of using nonsteroidal anti-inflammatory drugs (NSAIDs) before dental bleaching sessions in the dental office on postoperative sensitivity.

Methods

The review is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses checklist and registered on International Prospective Register of Systematic Reviews under number CRD42020210054. Randomized clinical trials published in the English language that compared the preventive use of NSAIDs with a placebo on the sensitivity resulting from dental bleaching in the dental office were selected, with no limitation on the year of publication. The electronic searches took place in PubMed/MEDLINE, Scopus, Web of Science, and Cochrane Library and were carried out independently by two researchers. A total of 30 articles were obtained; seven were selected according to the inclusion criteria.

Results

No significant differences were found in the reduction of dental sensitivity between the experimental group compared to the placebo during the session (p=0.32; mean difference [MD]=−0.30; 95% CI, −0.88 to 0.29), immediately after the session (p=0.22; MD=−0.29; 95% CI, −0.75 to 0.17), up to 1 hour later (p=0.10; MD=−0.94; 95% CI, −2.06 to 0.18), and between 1 and 24 hours after the procedure (p=0.78; MD=−0.11; 95% CI, −0.90 to 0.68). The incidence of sensitivity between the groups also did not show statistically relevant differences (p=0.60; MD=1.15; 95% CI, 0.69–1.92). Furthermore, none of the studies reported side effects in any patient.

Conclusion

This systematic review and meta-analysis indicates that the use of NSAIDs before dental office bleaching is not effective in reducing dental sensitivity during or up to 24 hours after the procedure. In addition, there was no difference in the incidence of sensitivity between the experimental and placebo groups.
A Satisfaction Study on the Expenditure Performance of Local Governments: Focusing on the participatory budgeting of Chungcheongnam-do
Authors:   The Korean Association for Local Public Enterprises, Lee Kwang-Won
Published: September 2022

In January 2021, the Local Autonomy Act was completely amended, and the era of 'decentralization 2.0' came into operation. The core of local autonomy can be said to be resident autonomy and fiscal decentralization, and the key to securing the soundness of local autonomy can be said to reflect the preferences of the residents well. This can be shown by how satisfied the residents are with the budget organized through the resident participation in the budget making process.
The purpose of this study is to examine the satisfaction of residents in Chungcheongnam-do with respect to the direction of fiscal expenditure and next year's investment in the Chungcheongnam-do participation budgeting. As a result of a survey on fiscal expenditure satisfaction and future investment directions for budgeting in Chungcheongnam-do, it was found that social welfare, general public administration, public order, and safety were generally dissatisfied. As a result of a survey on the direction of future fiscal expenditure investment adjustment, it was found that an increase in public order and safety and environmental fields was needed, and cuts were needed in general public administration and social welfare fields. In addition, it is also necessary to present a direction for seeking mid- to long-term and sustainable policy projects rather than one-time short-term projects in future fiscal expenditure investments.
Environmental filtering and low trait redundancy characterise fish assemblages in Lake Mamo, Orinoco River floodplain, Venezuela
Authors:   La Salle Foundation of Natural Sciences, Echevarría Gabriela ,   Independent Researcher, Quito, Ecuador, González Nirson ,   La Salle Foundation of Natural Sciences
Published: September 2022

The study of assembly rules of fish communities in Neotropical floodplain lakes represents a major interest in community ecology due to their high species diversity and environmental variation, both spatial and temporal. In this study, assembly rules of freshwater fishes in Lake Mamo were explored. The main goals of this research were to analyse the seasonal variations in taxonomic and functional diversities of fishes in sandbanks and patches of aquatic macrophytes, in order to identify whether the fish assemblages are organised according to environmental filtering or limiting similarity, and to explore the relationships between taxonomic and functional diversity to determine if fish assemblages are either functionally redundant or complementary. In both mesohabitats, fishes were collected using seine nets during four hydrological seasons corresponding to low waters, rising waters, high waters and falling waters. Taxonomic and functional structure of fish assemblages in each habitat and across hydrological seasons was examined through multidimensional scaling (MDS), PERMANOVAs and principal co-ordinate analyses. Seasonal variations in taxonomic diversity were determined through Fligner tests of Shannon diversity indices, and for functional diversity, of functional richness (FRich), functional dispersion (FDisp), functional evenness (FEve) and functional divergence (FDiv). Null model analyses were used to determine if the functional indices diverged from randomness across hydrological seasons. Finally, relationships between functional indices and Shannon diversity were explored using linear, power, asymptotic and logistic models. There were significant differences in taxonomic and functional composition between mesohabitats and more markedly across hydrological seasons. All fish assemblages were significantly underdispersed at all instances, while functional evenness was higher than expected in both mesohabitats during low waters, signaling both a strong environmental filtering and niche packing. There were significant linear associations between the Shannon diversity and functional dispersion and between the Shannon diversity and functional evenness, suggesting that functional redundancy in these assemblages is low. In Lake Mamo, fish assemblages are filtered first by seasonality and then by habitat type. As more species are added to the assemblages, niches are more packed in the functional space, but the number of traits increases at a constant rate. This means that if a lake becomes impaired as a consequence of potential oil spills, the loss of fish species could represent also the loss of traits and functions in the ecosystem.
Personalizing configuration for atrial fibrillation external electrical cardioversion to improve first shock efficacy
Authors: Massaro Giulia , Spagni Stefano , Martignani Cristian , Bettazzoni Luca , Spadotto Alberto , Ziacchi Matteo , Biffi Mauro , Galiè Nazzareno , Boriani Giuseppe , Frisoni Jessica , Diemberger Igor
Published: September 2022

Background

Despite the common use of biphasic electrical cardioversion (ECV) to convert atrial fibrillation (AF), we lack definite recommendations on electrode configuration.

Methods

We adopted a quasi-experimental design enrolling all candidates to ECV for AF. In the first stage, two units were involved, one using antero-apical pads (AAP) and the second antero-posterior adhesive patches (APP). These data enabled the creation of a decision algorithm to personalize the ECV approach, which was subsequently validated during the second stage.

Results

A total of 492 patients were enrolled overall. In the first stage, APP and AAP presented similar conversion rates (87.4 vs. 86.9% at first attempt of a step-up protocol, P = 0.661). While body surface area (BSA) ≤2.12 m2 was an independent predictor in the overall population, the two components (height and weight) acted differently in the two configurations: being height ≤1.73 m2 a significant cut-off value in the AAP subgroup, and weight <83 kg in the APP subgroup. Considering these cut-offs, we developed a decision algorithm for electrode configuration. In the second stage, algorithm validation confirmed an improvement in the first shock efficacy with respect to the results of the first stage (93.2 vs. 87.2%, P = 0.025), with a significant reduction in shock impedance (70.8 ± 15.3 vs. 81.8 ± 15.6, P < 0.001).

Conclusion

Patients with high BSA require high energy shocks for sinus rhythm restoration with ECV. Weight seems to affect more APP configuration, while height seems to impact more for the AAP. These findings have the potential to optimize ECV in clinical practice.
Evaluating anxiety in elective coronary angiography study: rationale, design, and study methodology
Authors: Palandacic Anja Kokalj , Radez Jerica , Ucman Sasa , Lainscak Mitja , Sarotar Brigita Novak
Published: September 2022

Aims

Prevalence of anxiety disorder in coronary artery disease reaches up to 15% and about half of patients with coronary artery disease have anxiety or depression comorbidity. Prevalence of anxiety in patients undergoing percutaneous coronary intervention ranges 24–72%. Depression can often overlap with anxiety symptoms and the evaluation of anxiety in elective coronary angiography study (ANGST) aims to determine the prevalence of anxiety by excluding patients with comorbid depressive symptoms. ANGST also aims to determine how anxiety correlates with psychological parameters (personality traits, coping strategies) and with outcome of elective coronary angiography (ECA).

Methods

We will conduct a prospective single-center cross-section study in patients undergoing ECA. Anxiety will be evaluated at four time points using self-rating questionnaires: 14 days prior to ECA; 2–4 h before ECA; 24 h after ECA, but prior to discharge; and 4–6 weeks after discharge. The primary outcome of ANGST is the burden of anxiety experienced by patients without depressive symptoms and a correlation of anxiety with ECA outcome.

Conclusion

Our study aims to provide evidence on which personality traits and coping strategies affect the levels of anxiety. We will also determine psychometric properties of the two questionnaires used in our study. The results will have implications for improvement of interventions designed to recognize anxiety and will offer future research of psychological and/or pharmacological interventions to reduce the burden of anxiety.
The positive impact of wooden material on educational processes in the environment of Slovenian wooden kindergartens
Authors: Hanták Jakub , Končeková Danica
Published: September 2022

Several scientific studies confirm that the colors, structures or materials used in the physical environment of interiors affect the human psyche. Wood, as a material applied in the interior spaces of buildings, is an attractor that, in addition to its static and structural properties with high environmental responsibility, also brings other benefits to users. It has a much greater impact on the society than we might think. The topic of applying sustainable materials and transforming them into newly-built, valuable and cultural architecture is currently also popular in connection with the new initiative the New European Bauhaus. The initiative has ambitions to use the existing national and international legislative frameworks, and to set sustainability rules with an interest in aesthetics and the involvement of communities in the creation of new living spaces. This paper aims to expand current scientific knowledge about the positive influence of wood material and its impact on educational processes in the architectural environment of kindergartens. Selected analyses and comparisons made it possible to assess whether the presence of wood material can positively affect the well-being of children in the physical environment of kindergartens. The article presents the results regarding children’s sensory perception, the feeling of safety, the feeling of a peaceful atmosphere. It aims to prove that interiors with exposed wood can improve the quality of teaching, can support social interaction and playful learning of children. The wood material is characterized in the presented author’s research as an interior, visible, massive material. Its design is authentic, with or without fine surface treatment, which does not degrade its visual-haptic-olfactory qualities. The study examines, analyzes and compares the architecture of kindergarten interiors in Slovenia. It interprets the results of practical research from the locations of Loče, Poljčane, Šoštanj, Polzela and Škofja Loka.