bluuebunny/crossref_metadata_2025 huggingface dataset:
Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities
Authors: Prieto M L , Ryu E , Jenkins G D , Batzler A , Nassan M M , Cuellar-Barboza A B , Pathak J , McElroy S L , Frye M A , Biernacka J M
Published: August 2016

Patients with bipolar disorder (BD) have a high prevalence of comorbid medical illness. However, the mechanisms underlying these comorbidities with BD are not well known. Certain genetic variants may have pleiotropic effects, increasing the risk of BD and other medical illnesses simultaneously. In this study, we evaluated the association of BD-susceptibility genetic variants with various medical conditions that tend to co-exist with BD, using electronic health records (EHR) data linked to genome-wide single-nucleotide polymorphism (SNP) data. Data from 7316 Caucasian subjects were used to test the association of 19 EHR-derived phenotypes with 34 SNPs that were previously reported to be associated with BD. After Bonferroni multiple testing correction, P<7.7 × 10−5 was considered statistically significant. The top association findings suggested that the BD risk alleles at SNP rs4765913 in CACNA1C gene and rs7042161 in SVEP1 may be associated with increased risk of ‘cardiac dysrhythmias’ (odds ratio (OR)=1.1, P=3.4 × 10−3) and ‘essential hypertension’ (OR=1.1, P=3.5 × 10−3), respectively. Although these associations are not statistically significant after multiple testing correction, both genes have been previously implicated with cardiovascular phenotypes. Moreover, we present additional evidence supporting these associations, particularly the association of the SVEP1 SNP with hypertension. This study shows the potential for EHR-based analyses of large cohorts to discover pleiotropic effects contributing to complex psychiatric traits and commonly co-occurring medical conditions.
Location-specific immunodetection of cocaine on banknotes
Authors: van der Heide Susan , Cunningham Andrew , Hardwick Sheila , Russell David A.
Published: August 2016

A novel in-gel bioanalytical immunodetection method has been developed to determine both the presence and the location of cocaine on the surface of banknotes.
Colorimetric detection of hydrogen peroxide using silver nanoparticles with three different morphologies
Authors: Zhang Laiping , Li Li
Published: August 2016

We attempted to investigate the colorimetric detection of H2O2 using silver nanoparticles (AgNPs) with three different morphologies (triangular, spherical, and cubic), and the activity of AgNPs toward H2O2 increased in the order of cubic < spherical < triangular AgNPs.
ISVR modeling of an interferon gamma (IFN-γ) biosensor based on graphene
Authors: Akbari Elnaz , Buntat Zolkafle , Nilashi Mehrbakhsh , Afroozeh Abdolkarim , Farhang Yousef , Zeinalinezhad Alireza
Published: August 2016

Nowadays the detection of proteins plays a crucial role for the early diagnosis of diseases.
A nanocomposite of ferrocenoyl glutaric acid hydrazone and multiwalled carbon nanotubes as a sensor for azide ions
Authors: Tiwari Ida , Gupta Mandakini , Rai Abhishek , Mishra Lallan
Published: August 2016

A nanocomposite containing ferrocenoyl glutaric acid hydrazone and multiwalled carbon nanotubes (MWCNTs) has been synthesized and characterized for its structural, morphological and electrochemical properties.
A multiresidue analytical method for trace level determination of antibiotics and antiretroviral drugs in wastewater and surface water using SPE-LC-MS/MS and matrix-matched standards
Authors: Ngumba Elijah , Kosunen Päivi , Gachanja Anthony , Tuhkanen Tuula
Published: August 2016

Comparison of matrix-matched and internal standard calibration methods in the analysis of selected antibiotics and antiretroviral drugs in urban waters by SPE-LC-MS/MS.
Rapid analysis of trace drugs and metabolites using a thermal desorption DART-MS configuration
Authors: Sisco Edward , Forbes Thomas P. , Staymates Matthew E. , Gillen Greg
Published: August 2016

The need to analyze trace narcotic samples rapidly for screening or confirmatory purposes is of increasing interest to the forensic, homeland security, and criminal justice sectors.
A versatile UHPLC–MSMS method for simultaneous quantification of various alcohol intake related compounds in human urine and blood
Authors: Monošík Rastislav , Dragsted Lars Ove
Published: August 2016

The method includes ethanol intake markers as well as selected metabolites potentially affected by ethanol.
Specificity of high resolution analysis of naphthenic acids in aqueous environmental matrices
Authors: Brunswick Pamela , Hewitt L. Mark , Frank Richard A. , van Aggelen Graham , Kim Marcus , Shang Dayue
Published: August 2016

The effect of environmental interferences and sample container pH adjustment on total naphthenic acids is reported during application of liquid chromatography with quadrupole time-of-flight mass spectrometry detection (LC/QToF).
A portable chromium ion detection system based on a smartphone readout device
Authors: Yu Shiting , Xiao Wei , Fu Qiangqiang , Wu Ze , Yao Cuize , Shen Haicong , Tang Yong
Published: August 2016

The portable detection system based on a smartphone readout device is a potential tool for environmental monitoring.
Multiplexed detection of pathogen-specific DNA using engineered zinc finger proteins without target amplification
Authors: Kim Moon-Soo , Kim Juhwa
Published: August 2016

Direct chemiluminescence detection of double-stranded DNA specific for bacterial pathogens using engineered zinc finger proteins (ZFPs).
A fluoride-selective electrode (Fse) for the quantification of fluoride in lithium-ion battery (Lib) electrolytes
Authors: Wilken A. , Kraft V. , Girod S. , Winter M. , Nowak S.
Published: August 2016

In this work, a fluoride-selective electrode (FSE) was applied with regard to the analysis of fluoride in lithium hexafluorophosphate-based lithium-ion battery (LIB) electrolytes.
Durable proteo-hybrid vesicles for the extended functional lifetime of membrane proteins in bionanotechnology
Authors: Khan Sanobar , Li Mengqiu , Muench Stephen P. , Jeuken Lars J. C. , Beales Paul A.
Published: August 2016

Significant enhancement of membrane protein functional durability is demonstrated when reconstituted in hybrid lipid–block copolymer vesicles compared to conventional proteoliposomes.
Self-assembled sulfur/reduced graphene oxide nanoribbon paper as a free-standing electrode for high performance lithium–sulfur batteries
Authors: Liu Yang , Wang Xuzhen , Dong Yanfeng , Tang Yongchao , Wang Luxiang , Jia Dianzeng , Zhao Zongbin , Qiu Jieshan
Published: August 2016

Graphene nanoribbon based paper fabricated through S2− reduction and evaporation induced self-assembly processes shows potential application in lithium–sulfur batteries.
Substrate-controlled switchable asymmetric annulations to access polyheterocyclic skeletons
Authors: Wang Kai-Kai , Wang Pan , Ouyang Qin , Du Wei , Chen Ying-Chun
Published: August 2016

Substrate-controlled switchable asymmetric annulations of Morita–Baylis–Hillman carbonates from isatins and α-cyano-α,β-unsaturated ketones catalysed by cinchona-derived tertiary amines, giving tetrahydrofuro[2′,3′:4,5]pyrano[2,3-b]indoles or spirooxindoles incorporating a cyclopentene motif, were disclosed.
Photocatalytic decarboxylation of lactic acid by Pt/TiO2
Authors: Liu Kaituo , Litke Anton , Su Yaqiong , van Campenhout Bart G. , Pidko Evgeny A. , Hensen Emiel J. M.
Published: August 2016

A photocatalytic route for the conversion of lactic acid to acetaldehyde in water is demonstrated.
An autocatalytic DNA machine with autonomous target recycling and cascade circular exponential amplification for one-pot, isothermal and ultrasensitive nucleic acid detection
Authors: Sun Xinya , Wang Li , Zhao Mingsha , Zhao Changzhi , Liu Shufeng
Published: August 2016

An autonomous target recycling and cascade circular exponential amplification strategy was proposed for the one-pot, isothermal and ultrasensitive detection of target DNA.
Aliphatic–aromatic stacking interactions in cyclohexane–benzene are stronger than aromatic–aromatic interaction in the benzene dimer
Authors: Ninković D. B. , Vojislavljević-Vasilev D. Z. , Medaković V. B. , Hall M. B. , Brothers E. N. , Zarić S. D.
Published: August 2016

Stacking interactions between cyclohexane and benzene were studied in crystal structures from the Cambridge Structural Database and by ab initio calculations.
Modelling photophysical properties of metal–organic frameworks: a density functional theory based approach
Authors: Wilbraham Liam , Coudert François-Xavier , Ciofini Ilaria
Published: August 2016

Photoluminescence of zinc and cadmium-based metal–organic frameworks has been characterized using density functional theory (DFT) and time-dependent DFT.
Establishing the pivotal role of local aromaticity in the electronic properties of boron-nitride graphene lateral hybrids
Authors: Otero Nicolás , El-kelany Khaled E. , Pouchan Claude , Rérat Michel , Karamanis Panaghiotis
Published: August 2016

Within an attempt to unravel the conundrum of irregular bandgap variations in hybrids of white-graphene (hBN) and graphene (G) observed in both experiment and theory, strong proofs about the decisive role of aromaticity in their electronic properties are brought to light.
Mechanism of the potential-triggered surface transformation of germanium in acidic medium studied by ATR-IR spectroscopy
Authors: Nayak Simantini , Erbe Andreas
Published: August 2016

During the electrochemical surface transformation of Ge(100) and Ge(111) surfaces from an –OH to an –H terminated surface, different potential dependent transient species are observed.
Photocycloaddition reaction of atropisomeric maleimides: mechanism and selectivity
Authors: Chang Xue-Ping , Zheng Yiying , Cui Ganglong , Fang Wei-Hai , Thiel Walter
Published: August 2016

We report a density functional study on the mechanism of the [2+2] photocyclization of atropisomeric maleimides.
Simulations of the water exchange dynamics of lanthanide ions in 1-ethyl-3-methylimidazolium ethyl sulfate ([EMIm][EtSO4]) and water
Authors: Tu Yi-Jung , Allen Matthew J. , Cisneros G. Andrés
Published: August 2016

Molecular dynamics simulations have been carried out to explain the water-exchange rates of lanthanide ions in water and water/[EMIm][EtSO4] observed from 17O-NMR experiments. Our simulations are in agreement with experimental results with respect to water-exchange trends.
Pd–In intermetallic alloy nanoparticles: highly selective ethane dehydrogenation catalysts
Authors: Wu Zhenwei , Wegener Evan C. , Tseng Han-Ting , Gallagher James R. , Harris James W. , Diaz Rosa E. , Ren Yang , Ribeiro Fabio H. , Miller Jeffrey T.
Published: August 2016

2 nm PdIn intermetallic alloy (cubic, CsCl type) nanoparticle catalyst was near 100% selective to ethane dehydrogenation at 600 °C (at 15% conversion) with a dehydrogenation TOR almost 10 times higher than that of monometallic Pd.
Catalytic deoxygenation during cellulose fast pyrolysis using acid–base bifunctional catalysis
Authors: Zhang Jing , Choi Yong S. , Shanks Brent H.
Published: August 2016

Acid–base bifunctional catalysts gave the highest deoxygenation activity while sacrificing relatively less carbon than the strictly acidic or basic catalysts.
A highly aluminum-doped β-isomer Keggin-type tungstoaluminate
Authors: Han Zhangang , Zhang Huixia , Yan Jinshuang , Zhai Xueliang
Published: August 2016

A highly Al-doped β-isomer Keggin-type cluster was synthesized and characterized.
A selective fluorescent sensor for Zn2+ based on aggregation-induced emission (AIE) activity and metal chelating ability of bis(2-pyridyl)diphenylethylene
Authors: Gabr Moustafa T. , Pigge F. Christopher
Published: August 2016

A bis(2-pyridyl)tetraarylethylene exhibits selective “turn-on” fluorescence enhancement in the presence of Zn2+ ions.
Interactions between uranium(vi) and phosphopeptide: experimental and theoretical investigations
Authors: Wu Qun-Yan , Zhai Fu-Wan , Liu Yang , Yuan Li-Yong , Chai Zhi-Fang , Shi Wei-Qun
Published: August 2016

A phosphorylated pentapeptide (WpTPpTW, P1) motif was designed as a model to mimic possible U(vi) coordination sites of genuine phosphorylated proteins.
Photochemical transformations of thiolated polyethylene glycol coatings on gold nanoparticles
Authors: Louie Stacey M. , Gorham Justin M. , McGivney Eric A. , Liu Jingyu , Gregory Kelvin B. , Hackley Vincent A.
Published: August 2016

Photochemical reactions can cause significant transformations of manufactured nanomaterials and their surface coatings in sunlit environments. In this study, loss of thiolated polyethylene glycol from gold nanoparticle surfaces by chain scission was observed under UV irradiation and resulted in diminished colloidal stability.
Attosecond science in atomic, molecular, and condensed matter physics
Authors: Leone Stephen R. , Neumark Daniel M.
Published: August 2016

Attosecond science represents a new frontier in atomic, molecular, and condensed matter physics, enabling one to probe the exceedingly fast dynamics associated with purely electronic dynamics in a wide range of systems. This paper presents a brief discussion of the technology required to generate attosecond light pulses and gives representative examples of attosecond science carried out in several laboratories. Attosecond transient absorption, a very powerful method in attosecond science, is then reviewed and several examples of gas phase and condensed phase experiments that have been carried out in the Leone/Neumark laboratories are described.
Antidiabetic (type 2) effects of Lactobacillus G15 and Q14 in rats through regulation of intestinal permeability and microbiota
Authors: Tian Peijun , Li Baolong , He Canxia , Song Wei , Hou Aiju , Tian Sicong , Meng Xinyu , Li Kaikai , Shan Yujuan
Published: August 2016

LactobacillusG15 and Q14 alleviated type 2 diabetes through regulation of gut microbiota and gut permeability.
Mugil cephalus roe oil obtained by supercritical fluid extraction affects the lipid profile and viability in cancer HeLa and B16F10 cells
Authors: Rosa A. , Piras A. , Nieddu M. , Putzu D. , Cesare Marincola F. , Falchi A. M.
Published: August 2016

We explored the changes in viability and lipid profile occurring in cancer cells, melanoma cells (B16F10 cells) and cervical carcinoma cells (HeLa cells), when exposed to an n-3 PUFA-rich oil obtained by SFE-CO2extraction fromMugil cephalusprocessed roe (bottarga).
Assessment of the prebiotic effect of quinoa and amaranth in the human intestinal ecosystem
Authors: Gullón Beatriz , Gullón Patricia , Tavaria Freni K. , Yáñez Remedios
Published: August 2016

Quinoa and amaranth belong to the group of the so called “superfoods” and have a nutritional composition that confers multiple benefits.
Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
Authors: Mileski Ksenija S. , Ćirić Ana D. , Trifunović Snežana S. , Ristić Mihailo S. , Soković Marina D. , Matevski Vlado S. , Tešević Vele V. , Jadranin Milka B. , Marin Petar D. , Džamić Ana M.
Published: August 2016

Pseudomonas aeruginosa treated with Heracleumorphanidis showed lower twitching and flagella motility.
Microfluidic partition with in situ biofabricated semipermeable biopolymer membranes for static gradient generation
Authors: Luo Xiaolong , Vo Thanh , Jambi Fahad , Pham Phu , Choy John S.
Published: August 2016

We report the biofabrication of robust and semipermeable biopolymer membranes that partition microchannels and enable the generation of static gradients.
Facile synthesis of nonsymmetrical heteroaryl-substituted triarylmethanes via the FeCl3·6H2O-catalyzed two-step Friedel–Crafts-type reaction
Authors: Ruengsangtongkul S. , Taprasert P. , Sirion U. , Jaratjaroonphong J.
Published: August 2016

A mild, facile, atom economical and efficient method was described for the synthesis of functionalized nonsymmetrical heteroaryl-substituted triarylmethanes via the two step Friedel–Crafts-type reaction catalyzed by FeCl3·6H2O under “open-flask” at room temperature.
ADMET and TAD chemistry: a sustainable alliance
Authors: Vlaminck L. , De Bruycker K. , Türünç O. , Du Prez F. E.
Published: August 2016

Post-polymerisation functionalisation and subsequent crosslinking of unsaturated ADMET derived polymers were performed via the versatile and ultrafast 1,2,4-triazoline-3,5-dione click chemistry.
Improvement of chemical ordering and magnetization dynamics of Co–Fe–Al–Si Heusler alloy thin films by changing adjacent layers
Authors: Banerjee Chandrima , Loong Li Ming , Srivastava Shalabh , Pal Semanti , Qiu Xuepeng , Yang Hyunsoo , Barman Anjan
Published: August 2016

We used Brillouin light scattering to demonstrate a correlation between the improvement of dynamic magnetic properties and chemical ordering of Co2FeAl0.5Si0.5 Heusler alloy thin films by varying adjacent layers.
Luminescence and energy transfer in a color tunable CaY4(SiO4)3O:Ce3+, Mn2+, Tb3+phosphor for application in white LEDs
Authors: Wang Lili , Moon Byung Kee , Park Sung Heum , Kim Jung Hwan , Shi Jinsheng , Kim Kwang Ho , Jeong Jung Hyun
Published: August 2016

White light with CIE coordinate (0.3553, 0.3338) was generated in the sample.
An update on hypoallergenicity of peanut and soybean: where are we now?
Authors: Shamoon Muhammad , Sajid Muhammad Wasim , Safdar Waseem , Haider Junaid , Omar Mukama , Ammar Alfarga , Sharif Hafiz Rizwan , Khalid Saud , Randhawa Muhammad Atif
Published: August 2016

Legumes are one of the major sources of proteins and positively correlate with the development of modern society. At the same time, unfortunately, they significantly contribute to the rising prevalence of food allergy.
Fabrication of a micro-nanostructured superhydrophobic aluminum surface with excellent corrosion resistance and anti-icing performance
Authors: Zheng Shunli , Li Cheng , Fu Qitao , Xiang Tengfei , Hu Wei , Wang Jing , Ding Shibing , Liu Panjin , Chen Zhong
Published: August 2016

Synergy is the key to realizing superhydrophobicity. The as-prepared superhydrophobic Al surface possesses both excellent corrosion resistance and anti-icing performance.
Organocatalytic one-pot asymmetric synthesis of functionalized spiropyrazolones via a Michael-aldol sequential reaction
Authors: Amireddy Mamatha , Chen Kwunmin
Published: August 2016

An efficient organocatalytic method was developed for synthesizing functionalized spiropyrazolone derivatives by using a Michael-aldol consecutive reaction.
Pressurized liquid extraction of chlorinated polycyclic aromatic hydrocarbons from soil samples using aqueous solutions
Authors: Wang Xianli , Wu Junfeng , Liu Biao
Published: August 2016

Pressurized liquid extraction of chlorinated polycyclic aromatic hydrocarbons from soil samples using aqueous solutions.
Enhanced photocatalytic properties of ZnFe2O4-doped ZnIn2S4 heterostructure under visible light irradiation
Authors: Yang Wu , Chen Dezhi , Quan Hongying , Wu Shaolin , Luo Xubiao , Guo Lin
Published: August 2016

ZnFe2O4-doped ZnIn2S4 heterostructure was fabricated and showed enhanced photocatalytic performance under visible light irradiation.
Ion-exchange bonded H2Ti3O7 nanosheets-based magnetic nanocomposite for dye removal via adsorption and its regeneration via synergistic activation of persulfate
Authors: Jose Manu , Aswathi P. T. , Sriram K. , Parakh Priyadarshini , Prakash Halan , Shukla Satyajit
Published: August 2016

Magnetic nanocomposite consisting of H2Ti3O7 nanosheets and γ-Fe2O3 nanoparticles has been synthesized via ion-exchange bond formation and utilized for dye-removal application involving its regeneration through synergistic persulfate activation.
Understanding reactivity, aromaticity and absorption spectra of carbon cluster mimic to graphene: a DFT study
Authors: Saha Bapan , Bhattacharyya Pradip Kr.
Published: August 2016

Effect of doping B and/or N on the reactivity, aromaticity and absorption spectra of graphene and functionalized (–OH and –COOH) carbon cluster mimicking graphene is studied using DFT, DFRT and TD-DFT.
Percolative cobalt/silicon nitride composites with tunable negative electromagnetic parameters
Authors: Zhang Zi-dong , Cheng Chuan-bing , Han Xu
Published: August 2016

A 3D fishnet structure is formed in the Co/Si3N4 composites to obtain tunable negative electromagnetic parameters from 550 MHz to 1 GHz, which have potential applications in antennas, electromagnetic shielding and band-pass filter.
Synthetic methods and electrochemical applications for transition metal phosphide nanomaterials
Authors: Lu Yao , Wang Tianyi , Li Xinran , Zhang Guangxun , Xue Huaiguo , Pang Huan
Published: August 2016

Recent developments and challenges in transition metal phosphide nanomaterials, with a focus on synthetic methods and their electrochemical applications, have been stated carefully.
Green synthesis of tetrahydrobenzo[b]pyrans, pyrano[2,3-c]pyrazoles and spiro[indoline-3,4′-pyrano[2,3-c]pyrazoles catalyzed by nano-structured diphosphate in water
Authors: Maleki Behrooz , Nasiri Negar , Tayebee Reza , Khojastehnezhad Amir , Akhlaghi Hossien Ali
Published: August 2016

Preparation of nanostructured diphosphate Na2CaP2O7. Avoiding of any acid catalysts. The prepared catalyst is reusable and eco-friendly. The method is easy and contains simple experimental procedure.
Microperoxidase-11/metal–organic framework/macroporous carbon for detecting hydrogen peroxide
Authors: Gong Coucong , Chen Jingyi , Shen Yuan , Song Yonggui , Song Yonghai , Wang Li
Published: August 2016

Schematic illustrating of the fabrication and sensing principle of the newly develpoed H2O2 biosensor.
Investigation of a Fe–N–C catalyst for sulfur dioxide electrooxidation
Authors: Zhao Qing , Hou Ming , Jiang Shangfeng , Wang Shengli , Ai Jun , Zheng Limin , Shao Zhigang
Published: August 2016

A non-precious Fe–N–C catalyst is developed with the high SO2 electrooxidation performance.
Facile polyol synthesis of CuS nanocrystals with a hierarchical nanoplate structure and their application for electrocatalysis and photocatalysis
Authors: Fu Wenlong , Liu Maochang , Xue Fei , Wang Xixi , Diao Zhidan , Guo Liejin
Published: August 2016

The article describes a robust method for the facile polyol synthesis of high-quality CuS nanocrystals with a controlled hierarchical nanoplate structure.
Catalytic mechanism of acetolactate decarboxylase from Brevibacillus brevis towards both enantiomers of α-acetolactate
Authors: Zhao Chenxiao , Su Hao , Liu Yongjun
Published: August 2016

QM/MM calculations detail the conversion of both enantiomers of α-acetolactate to (R)-acetoin. (S)-α-acetolactate can be directly converted, whereas (R)-α-acetolactate has to firstly rearrange to the natural (S)-enantiomer through a carboxylate migration.
Copper-mediated etherification of arenes with alkoxysilanes directed by an (2-aminophenyl)pyrazole group
Authors: Selvakumar Jayaraman , Grandhi Gowri Sankar , Sahoo Harekrishna , Baidya Mahiuddin
Published: August 2016

(2-Aminophenyl)pyrazole directed copper mediated C–H etherification of (hetero)arenes is described.
Correction: Probing high temperature ferromagnetism and its paramagnetic phase change due to Eu3+ incorporation in ZnO nanophosphors
Authors: Rajan K. Jayanthi , Ganesan Kausalya , Lanka Satyanarayana , Bishnoi Swati , Sunkara Manorama V.
Published: August 2016

Correction for ‘Probing high temperature ferromagnetism and its paramagnetic phase change due to Eu3+ incorporation in ZnO nanophosphors’ by K. Jayanthi Rajan et al., RSC Adv., 2016, 6, 75669–75680.
Light-induced decarboxylation in a photo-responsive iron-containing complex based on polyoxometalate and oxalato ligands
Authors: Duan Yan , Waerenborgh João C. , Clemente-Juan Juan M. , Giménez-Saiz Carlos , Coronado Eugenio
Published: August 2016

A new iron-oxalato polyoxometalate exhibits a remarkable photocoloration effect in the solid state based entirely on an intramolecular process.
Porous nitrogen-rich carbon materials from carbon self-repairing g-C3N4 assembled with graphene for high-performance supercapacitor
Authors: Ding Yangbin , Tang Yanhong , Yang Liming , Zeng Yunxiong , Yuan Jili , Liu Tian , Zhang Shuqu , Liu Chengbin , Luo Shenglian
Published: August 2016

Porous nitrogen-rich carbon derived from carbon self-repairing g-C3N4 with improved conductivity and more active sites exhibited high capacitance and good cycling performance due to the oxygen-containing groups and the carbon atoms close to the nitrogen as confirmed by XPS.
Highly selective ratiometric peptide-based chemosensors for zinc ions and applications in living cell imaging: a study for reasonable structure design
Authors: Yang Jingchang , Rong Huan , Shao Ping , Tao Yanduo , Dang Jun , Wang Peng , Ge Yushu , Wu Jiang , Liu Dan
Published: August 2016

The relationship between the structure and activity for the fluorescent sensing of zinc ions with H2L peptides has been studied experimentally and computationally.
Nanoscale LnMOF-functionalized nonwoven fibers protected by a polydimethylsiloxane coating layer as a highly sensitive ratiometric oxygen sensor
Authors: Xu Xiao-Yu , Yan Bing
Published: August 2016

Nanoscale SUMOF-6-Eu functionalized nonwoven polypropylene films protected by a polydimethylsiloxane (PDMS) coating layer have been fabricated and used for ratiometric oxygen sensing.
Tunable optical properties of OH-functionalised graphene quantum dots
Authors: Geethalakshmi K. R. , Ng Teng Yong , Crespo-Otero Rachel
Published: August 2016

Functionalisation with OH groups can tune the optical properties of Graphene oxide quantum dots (GO-QDs). Selective functionalisation of positions with large electron–hole separation offers a strategy to control the optical gap and photoluminescence properties.
Engineering ancestral protein hyperstability
Authors: Romero-Romero M. Luisa , Risso Valeria A. , Martinez-Rodriguez Sergio , Ibarra-Molero Beatriz , Sanchez-Ruiz Jose M.
Published: August 2016

Many experimental analyses and proposed scenarios support that ancient life was thermophilic. In congruence with this hypothesis, proteins encoded by reconstructed sequences corresponding to ancient phylogenetic nodes often display very high stability. Here, we show that such ‘reconstructed ancestral hyperstability’ can be further engineered on the basis of a straightforward approach that uses exclusively information afforded by the ancestral reconstruction process itself. Since evolution does not imply continuous progression, screening of the mutations between two evolutionarily related resurrected ancestral proteins may identify mutations that further stabilize the most stable one. To explore this approach, we have used a resurrected thioredoxin corresponding to the last common ancestor of the cyanobacterial, Deinococcus and Thermus groups (LPBCA thioredoxin), which has a denaturation temperature of ∼123°C. This high value is within the top 0.1% of the denaturation temperatures in the ProTherm database and, therefore, achieving further stabilization appears a priori as a challenging task. Nevertheless, experimental comparison with a resurrected thioredoxin corresponding to the last common ancestor of bacteria (denaturation temperature of ∼115°C) immediately identifies three mutations that increase the denaturation temperature of LPBCA thioredoxin to ∼128°C. Comparison between evolutionarily related resurrected ancestral proteins thus emerges as a simple approach to expand the capability of ancestral reconstruction to search sequence space for extreme protein properties of biotechnological interest. The fact that ancestral sequences for many phylogenetic nodes can be derived from a single alignment of modern sequences should contribute to the general applicability of this approach.
Non-neuronal cardiac cholinergic system influences CNS via the vagus nerve to acquire a stress-refractory propensity
Authors: Oikawa Shino , Kai Yuko , Tsuda Masayuki , Ohata Hisayuki , Mano Asuka , Mizoguchi Naoko , Sugama Shuei , Nemoto Takahiro , Suzuki Kenji , Kurabayashi Atsushi , Muramoto Kazuyo , Kaneda Makoto , Kakinuma Yoshihiko
Published: August 2016

We previously developed cardiac ventricle-specific choline acetyltransferase (ChAT) gene-overexpressing transgenic mice (ChAT tgm), i.e. an in vivo model of the cardiac non-neuronal acetylcholine (NNA) system or non-neuronal cardiac cholinergic system (NNCCS). By using this murine model, we determined that this system was responsible for characteristics of resistance to ischaemia, or hypoxia, via the modulation of cellular energy metabolism and angiogenesis. In line with our previous study, neuronal ChAT-immunoreactivity in the ChAT tgm brains was not altered from that in the wild-type (WT) mice brains; in contrast, the ChAT tgm hearts were the organs with the highest expression of the ChAT transgene. ChAT tgm showed specific traits in a central nervous system (CNS) phenotype, including decreased response to restraint stress, less depressive-like and anxiety-like behaviours and anti-convulsive effects, all of which may benefit the heart. These phenotypes, induced by the activation of cardiac NNCCS, were dependent on the vagus nerve, because vagus nerve stimulation (VS) in WT mice also evoked phenotypes similar to those of ChAT tgm, which display higher vagus nerve discharge frequency; in contrast, lateral vagotomy attenuated these traits in ChAT tgm to levels observed in WT mice. Furthermore, ChAT tgm induced several biomarkers of VS responsible for anti-convulsive and anti-depressive-like effects. These results suggest that the augmentation of the NNCCS transduces an effective and beneficial signal to the afferent pathway, which mimics VS. Therefore, the present study supports our hypothesis that activation of the NNCCS modifies CNS to a more stress-resistant state through vagus nerve activity.
Developing the Talents of Future Dysphagia Experts: A Conceptual Framework
Authors: Brady Susan L. , Wiliams Letha , Hakel Mark , Pape Theresa
Published: August 2016

This article addresses adult learning theory, social cognitive theory, and level of expertise and its effect upon professional growth and development. Training and education strategies to enhance skill acquisition and development related to dysphagia evaluation and treatment are discussed. In most areas of life, and especially in clinical circles, it is common to defer to the “experts”. Looking for external, third-party validation from the “experts” can be a comfortable solution to a difficult question or challenging issue. But who are these “experts”? More to the point, what specific characteristics makes a clinician a dysphagia expert and what is the pathway to attaining this level of expertise?
PUF‐based encryption method for IC cards on‐chip memories
Authors: Bai Yonghong , Wu Liji , Wu Xingjun , Li Xiangyu , Zhang Xiangmin , Wang Beibei
Published: August 2016

This Letter presents a self‐controlled physical unclonable function (PUF) circuit and its application in encrypting on‐chip memories of IC bank cards. The PUF circuit is based on cross‐coupled NAND gates. Voting and Hamming code address the stability of its outputs. The Monte Carlo simulation and field‐programmable gate array board are used for verification. The Voting method improves the error rate 79%. The Hamming codes and convertor can correct every error bits of PUF outputs. The PUF outputs, data address and time‐stamp are encrypted by SM4 (Chinese block cipher algorithm standard) to generate KEY. The data does XOR with the KEY.
Broadband transition between microstrip line and spoof SP waveguide
Authors: Xu Jie , Cui Yinjie , Guo Jian , Xu Zhengbin , Qian Cheng , Li Wenyuan
Published: August 2016

A broadband transition from microstrip line to spoof surface plasmon (SP) waveguide is proposed. The transition transforms the guided wave into a spoof SP polariton in a broad microwave frequency band. A back‐to‐back transition sample is fabricated using the proposed method. Good agreement between the measurement and simulation is obtained. The measured results show an insertion loss <2 dB and a return loss below −11 dB from 2.2 to 10 GHz. The proposed broadband transition may pave a way for advanced conventional plasmonic integrated microwave devices and circuits.
Passive localisation of mixed far‐field and near‐field sources using uniform circular array
Authors: Xue Bing , Fang Guangyou , Ji Yicai
Published: August 2016

Using uniform circular array, a passive localisation algorithm is presented for the scenarios where both far‐field and near‐field narrow‐band signals may exist synchronously. The differencing matrix and the orthogonal projection matrix of the signal subspace are built to classify the mixed signals and to estimate the 2D direction‐of‐arrivals (DOAs) of the near‐field signals (NFSs). Then, the covariance matrix of signals is decomposed to obtain the noise subspace. Meanwhile, 1D multiple signal classification (MUSIC) is used to estimate the ranges of the NFSs and 2D MUSIC is used to estimate the DOAs of far‐field signals (FFSs). Compared with two‐stage MUSIC (TSMUSIC), the proposed algorithm can provide higher resolution for the DOAs so that the signals can be separated. In addition, compared with TSMUSIC and four‐order cumulant MUSIC, the proposed algorithm has higher accuracy for localisation of both FFSs and NFSs. Simulation results are carried out to verify the performance of the proposed algorithm.
Silicon photodetectors with triple p–n junctions in CMOS technology at 650‐ and 850‐nm wavelengths
Authors: Tsai Y.‐C. , Zhong Y.‐N. , Chou F.‐P. , Huang C.‐A. , Hsin Y.‐M.
Published: August 2016

A triple p–n junction Si photodetector using 0.25‐μm standard CMOS process at 650‐ and 850‐nm wavelengths is presented and investigated. Triple p–n junctions are formed vertically by n+‐implant/p‐well (N+/HVPW), p‐well/n+‐buried layer (HVPW/NBL), and n+‐buried layer/p‐substrate (NBL/P‐sub) junctions to attain a wavelength‐dependent response. The responsivity and pulse response were characterised in different bias schemes. Measured photocurrents from HVPW/NBL and NBL/P‐sub junctions under reverse biasing and a floating electrode on N+‐HVPW showed the smallest FWHM values. The −3 dB bandwidth of 1.9 GHz converted from pulse measurement is the highest result ever reported in 654‐nm wavelength using standard CMOS technology. The proposed triple p–n junction Si photodetector with bias schemes shows combined excellent performance in 650‐ and 850‐nm wavelengths.
Parallel computation of transient stability using symplectic Gauss method and GPU
Authors: Liao Xiaobing , Wang Fangzong
Published: August 2016

This study presents a new parallel algorithm for power system transient stability computation based on symplectic Gauss method. The s‐stage 2s‐order symplectic Gauss method is used to convert the differential‐algebraic system simultaneously at s time points into a set of non‐linear algebraic equations, and the algebraic system is then solved by Newton method. Based on the block matrix characteristics, the solution of the linear equations involved in Newton method's process can be divided into two parts: the first part is fully parallelisable in time, and the second part is solved by preconditioned GMRES method while an efficient preconditioner has been proposed based on the V‐transformation. For test, the proposed algorithm is implemented on three programming models, the first is the traditional central processing unit (CPU) computing, the second is CPU‐single graphics processing unit (GPU) cooperative computing, and the last one is CPU‐multiple GPUs cooperative computing. The results show that, the proposed parallel algorithm is accurate, has good convergence, and has good scalability both in the problem size and in the number of used GPU.
Multi‐objective transmission expansion planning in a smart grid using a decomposition‐based evolutionary algorithm
Authors: Qiu Jing , Dong Zhao Yang , Meng Ke , Xu Yan , Zhao Junhua , Zheng Yu
Published: August 2016

The integration of large‐scale renewable energy and demand response (DR) resources in smart grids have brought in emerging challenges for transmission expansion planning (TEP), particularly in terms of system security. The conventional TEP models have not fully addressed the cost and the feasibility of corrective control (CC) actions such as generation rescheduling and load curtailment under contingencies. Moreover, the optimality of CC depends on the pre‐contingency state, the post‐contingency state, as well as the existence and viability of the involved CC actions. In this study, first the authors have given the explicit definition of CC risk index (CCRI), which evaluates the expected system performance under a set of contingencies (i.e. risk of incurring security issues). With the authors’ improvement, the CCRI is now mathematically tractable and may have wide applications to TEP problems. Afterwards, the authors have proposed a multi‐objective TEP framework with tradeoffs between cost and risk. A relatively new yet superior multi‐objective evolutionary algorithm called the multi‐objective evolutionary algorithm (MOEA)/D is introduced and employed to find Pareto optimal solutions. The proposed model is numerically verified on the modified IEEE RTS 24‐bus and 118‐bus systems. According to the simulation results, the proposed model can provide information regarding variants of risks and coordinate the optimum planning and DR solutions.
Procurement of regulation services for a grid with high‐penetration wind generation resources: a case study of ERCOT
Authors: Du Pengwei , Hui Hailong , Lu Ning
Published: August 2016

This study presents two enhancements at the Electric Reliability Council of Texas (ERCOT) for coping with the uncertainties and variations brought by high penetration of wind generation resources (GRs). The first enhancement is the incorporation of a novel short‐term wind forecast algorithm into the look‐ahead dispatch process to improve the calculation of locational marginal prices and generation schedules. The second enhancement is the development of a multi‐time‐scale method for quantifying regulation service requirements considering the combined impact of wind variations on governor response, automatic generation control, and economic dispatch results. A simulation model that is capable of simulating all relevant scheduling and operation processes from a few seconds to a few hours is developed to verify the performance of the proposed method. The ERCOT operational model and historical data are used to demonstrate that the derived regulation requirements can meet the ERCOT reliability needs by considering additional generation variations and uncertainties caused by wind GRs. The proposed methods are readily applicable to other regional power grids with high penetration of variable GRs.
When spatial distribution unites with spatial contrast: an effective blind image quality assessment model
Authors: Yan Yaping , Du Songlin , Zhang Hongjuan , Ma Yide
Published: August 2016

Blind image quality assessment (BIQA), which aims to estimate the perceptual quality of images without any reference information, is a very important yet challenging task. Although human visual system is sensitive to degradations on both spatial contrast and spatial distribution, most of the existing structural degradation based BIQA models consider only one of them. This study introduces a novel BIQA model by taking into account degradations on both contrast and spatial distribution. First, the authors construct a multi‐threshold local tetra pattern (MTLTrP) instead of local binary pattern to measure the changes on spatial distribution. Second, Weber–Laplacian of Gaussian (WLOG) operator, which responds to intensity contrast in a small spatial neighbourhood, is proposed to extract local contrast features. Finally, the joint statistics of MTLTrP and WLOG are utilised for BIQA model learning. Experimental results on three large benchmark databases demonstrate that the proposed model outperforms state‐of‐the‐art BIQA models, as well as with several well‐known full reference quality assessment methods.
Dynamic delay risk assessing in supply chains
Authors: Lajimi Chokri , Boufaied Amine , Lamine Elyes , Korbaa Ouajdi
Published: August 2016

To be competitive, supply chains must be able to analyse and to evaluate, in real‐time, critical differences between the short‐term planned actions and the actual performed actions generating states of undesirable or unacceptable risk. The authors propose in this study, a method for monitoring the dynamic evolution of risk associated to delays affecting the transportation operations. They use the failure mode and effects analysis around failure scenarios and they evaluate risk using probability and cost. A failure scenario probability is estimated dynamically in discrete points based on event occurrences during the process execution. Delay risk is then assessed on‐line and preventive actions can be undertaken before execution ended. The implementation of this method is performed by monitoring a delivery process facing risks associated to delays in the transport stream.
Control strategies for solving the problem of traffic congestion
Authors: Huang Yi‐Sheng , Weng Yi‐Shun , Wu Weimin , Chen Bo‐Yang
Published: August 2016

Once a road is with a high traffic density over its loading, the traffic management has to face the fact that how to alleviate the traffic congestion and how to prevent new traffic jams from being happening in the neighbourhood. This study presents a new control strategy for alleviating the traffic congestion. For this purpose, the authors employ VISSIM to simulate and analyse of an urban traffic congestion problem. In addition, two kinds of traffic light orders are involved. On the other hand, an urban traffic network with three kinds of intersection is used to evaluate their new congestion control policy. Finally, they also demonstrate three scenario cases low, middle, and heavy traffic flow works to compare with normal regular traffic light control rules, the multiline control strategies and their new control policy. Simulation results show that their new proposed traffic control policy is the best one among the others. It is worthy of note that their new proposed policy not only alleviates successfully the congestion problem but also prevents new traffic jams from being happening in the neighbourhood.
Electrical power generation by an optimised autonomous PV/wind/tidal/battery system
Authors: Askarzadeh Alireza
Published: August 2016

The main contributions of this study are to (i) incorporate tidal power into a hybrid PV/wind/battery renewable energy system and (ii) introduce a new metaheuristic technique named crow search algorithm (CSA) for optimisation of the PV/wind/tidal/battery system. For this aim, power equations of the different components are introduced and an objective function is defined based on the economic analysis of the system. The proposed CSA is then used to optimally size the PV/wind/tidal/battery system. On the case study, simulation results show that using tidal energy decreases the total cost of the system. Moreover, the proposed CSA produces better results in comparison with two well‐known metaheuristic methods, namely, particle swarm optimisation and genetic algorithm in terms of accuracy and run time.
Carrier mobility extraction method in ChGs in the UV light exposure
Authors: Saremi Mehdi
Published: August 2016

One of the significant advantages of the ultraviolet (UV) light exposure of chalcogenide glasses (ChGs), photodoping process, is in the application of programmable metallisation cells (PMCs) as a novel non‐volatile resistive memory. The memory state of a PMC is dictated by the formation or dissolution of a metallic filament in a ChG film between active metal and inert metal contacts. Owing to relatively rigid covalent bonds mixed with soft van der Waals interconnections, ChGs are able to form acceptor‐like traps where electrons are absorbed, and therefore electron mobility decreases compared with crystallised structures. The role of electrons in the interaction with ionic species in ChGs is inevitable. One the other hand, holes are considered as majority carries and their role in interaction with the system is also significant. Therefore, knowing carrier mobility in ChGs is essential. To extract carrier mobilities, for the first time a circuit setup accompanying with time constant extraction method for Ge30Se70 as a ChG material without and with UV light exposure is proposed. Owing to being straightforward, this method can be applied to other ChG materials as well as other light sources or even ionising radiation particles.
Life estimation and investigation of dielectric strength of multistressed high‐voltage epoxy micro and nanocomposites
Authors: Amin Muhammad , Khattak Abraiz , Ali Muhammad
Published: August 2016

Epoxy/silica micro and nanocomposites are prepared and subjected to multiple accelerated stresses along with neat epoxy for 9000 h in a specially fabricated chamber. Leakage current measurements were recorded after each weather cycle. Dielectric strength was also evaluated according to ASTM‐D149 after each 1000 h ageing. In the course of ageing time, neat epoxy was found with high dielectric loss and random rise in leakage current. In the case of both micro and nanocomposites, these properties indicated improvements over neat epoxy. By applying regression technique over leakage current measurements, relatively longer service lives of epoxy composites were estimated.
Power Doppler Quantification in Assessing Gestational Trophoblastic Neoplasia
Authors: Li Yuanwei , Tang Meng , Agarwal Roshan , Patel Daksha , Eckersley Robert , Barrois Guillaume , Roddie Mary , Dayal Linda , Savage Philip , Seckl Michael , Lim Adrian
Published: August 2016

Purpose The FIGO score cannot accurately stratify low-risk gestational trophoblastic neoplasia (GTN) patients who develop chemoresistance to single agent methotrexate chemotherapy. Tumour vascularisation is a key risk factor and its quantification may provide non-invasive way of complementing risk assessment.

Materials and Methods 187 FIGO-staged, low-risk GTN patients were prospectively recruited. Power Doppler ultrasound was analysed using a quantification program. Four diagnostic indicators were obtained comprising the number of colour pixels (NCP), mean dB, power Doppler quantification (PDQ), and percentage of colour pixels (%CP). Each indicator performance was assessed to determine if they could distinguish the subset of low-risk patients who became chemoresistant.

Results There were 111 non-resistant and 76 resistant patients. NCP performed best at distinguishing these two groups where the non-resistant group had an average 3435 (± 2060) pixels and the resistant group 6151 (± 3192) pixels (p < 0.001). PDQ and %CP showed significant differences (p < 0.001) but had poorer performance (area under ROC curves were 72 % and 67 % respectively compared with 75 % for NCP). The mean dB index was not significantly different (p = 0.133).

Conclusion Power Doppler ultrasound quantification shows potential for non-invasive assessment of tumour vascularity and can distinguish low-risk GTN patients who become chemoresistant from those who have an uncomplicated course with first line treatment.
The prospects for Paris: behavioral insights into unconditional cooperation on climate change
Authors: McEvoy David M. , Cherry Todd L.
Published: August 2016

Recent survey evidence from the United States suggests that most Americans support domestic policies to address climate change, and this support is not conditional on other countries’ commitment levels. The finding is somewhat perplexing because climate change is by definition a collective problem that requires a collective response. However, the question of why Americans support unconditional climate initiatives has not been addressed. We present survey evidence that shows a willingness to act alone is not the result of misunderstanding the collective nature of the climate problem, but rather people are driven by notions of responsibility, morality and global leadership.