bluuebunny/crossref_metadata_2025 huggingface dataset:
Les complications des avortements clandestins observées à la maternité de Befelatanana, Antananarivo
Authors: Rainibarijaona LNA , Hary Avotra DL , Mahefarisoa FNAT , Rakotoarivony VK , Andrianampanalinarivo HR
Published: May 2024

Introduction. Clandestine abortion is still frequent in Madagascar and is a public health problem. The complications are numerous and the mortality is still high. Our objectives are to describe the epidemiological aspects, to cite the abortive means used and to report its complications. Patients and methods. This is a retrospective descriptive study from 1st january to 31st december 2011 of illegal abortions at the maternity of Befelatanana, Antananarivo. Results. We had recorded 124 cases. The age groups were between 25 and 45 years; 51.61% were legally married and 41.91% were housewives. In our study, 20.96% had a history of voluntary termination of pregnancy, 70.96% had multiple gestures. In 60.48% of the cases, the women had practiced the abortive act themselves and the medicinal means (51.61%) were the most used means. Hemorrhagic complications by placental retention were observed in 58.87% of cases and 29.03% concerned by infectious complications. Uterine evacuation was used for 59.67% of cases. Ten cases of death (8.06%) were recorded. Conclusion. The complications of clandestine abortions remain a major public health problem in Madagascar. Sexual education and sensibilisation for the women about the use of contraceptives method would be a means to avoid or to minimize this scourge
Evaluation des altérations oculo-nerveuses au cours du glaucome primitif a angle ouvert chez des sujets sénégalais : apport du potentiel évoque visuel à damier
Authors: Nitiema R , Diaw M , Ouédraogo V , Sy M , Sow AK , Tiendrébéogo AJF , Loubano-Voumbi G , Seck/Diop A , Diagne SH , Touré M , Ba F , Ba-Diop A , Mbengue/Gaye A , Sar/Sarr FB , Ba A , Ba EHA , Ndoye/Roth PA , Diagne M , Gueye L , Samb A
Published: May 2024

Introduction. Visual evoked potentials (VEP) are frequently used in Europe for the diagnosis of glaucoma, unlike in sub-Saharan Africa. Thus we compare the visual evoked potentials of Senegalese glaucomatous subjects to control persons. Methods. Fourteen Senegalese were divided into two groups: Group 1 (G1) has consisted of 7 patients with primary open angle glaucoma and Group 2 (G2) formed by 7 control subjects. We conducted visual evoked potentials at Checkerboard in our subjects. Visual acuity, intraocular pressure and cup-disc nerve ratio were also evaluated. Results. Abnormalities of the cup-disc ratio were higher in G1 than G2 (Odds ratio = 0.000024 ; p = 0.001). Visual acuity was more impaired in glaucomatous subjects compared to controls (Odds ratio = 8.14 ; p= 0.018). The analysis of VEP showed that glaucomatous subjects had more reduced amplitude (Odds ratio = 8.436 ; p = 0.01) and more elongated latency (Odds ratio = 8.143 ; p= 0.023) than control persons. Correlations between latency impulses with acuity (r = -0.8177 ; p = 0.0004) and the cup-disc (r = -0.5668 ; p = 0.0345) were observed. Conclusion. Primary open angle glaucoma would cause nerve deterioration in blacks, and we recommend the use of visual evoked potential in the diagnosis and monitoring of glaucoma.
Percaya Diri Memoderasi Pengaruh Dasar Akuntansi, Hasil Belajar Matematika, dan Perilaku Belajar Terhadap Pemahaman Akuntansi
Authors: Tri Chandra Anggraini
Published: May 2024

Penelitian ini bertujuan untuk menganalisis pengaruh kemampuan akuntasi hasil belajar matematika dan perilaku belajar terhadap Tingkat pemahaman akuntansi secara parsial dan kepercayaan diri dapat memoderasi hubungan antara kemampuan dasar akuntansi, hasil belajar matematika dan perilaku belajar terhadap pemahaman akuntansi. Responden penelitian ini berjumlah 105 siswa akuntansi kelas X dengan Teknik analisis data menggunakan software warpPLS 6.0 dengan hasil Penelitian menunjukkan bahwa: (1) tidak ada hubungan kemampuan dasar akuntansi dan perilaku belajar dengan tingkat pemahaman akuntansi secara parsial (2) terdapat pengaruh antara hasil belajar siswa matematika dengan pemahaman tentang akuntansi (3) kepercayaan diri bukan merupakan variabel moderasi antara kemampuan dasar akuntansi, hasil belajar dari matematika, dan perilaku belajar terhadap tingkat pemahaman akuntansi secara parsial. Saran untuk penelitian selanjutnya dapat menggunakan aspek lain yang berkaitan dengan pemahaman akuntansi selain yang digunakan dalam penelitian ini dan dapat mengembangkan
Strategi Manajemen Perusahaan Yang Berfokus Masa Depan
Authors: Irgi Sahrinra
Published: May 2024

Teknologi Informasi (TI) telah menjadi inti strategi dalam persaingan bisnis melalui transformasi struktur industri. Penggunaan TI bukan hanya sebagai alat pendukung, tetapi menjadi bagian integral dari strategi perusahaan, terutama dalam hal perencanaan dan pengendalian manajemen organisasi. Artikel ini mengeksplorasi bagaimana TI dapat memberikan keunggulan strategis dan prinsip desain yang diperlukan untuk memanfaatkan keunggulan tersebut. TI memiliki dampak yang signifikan pada berbagai tingkat manajemen perusahaan. Mulai dari level eksekutif yang membutuhkan informasi strategis untuk pengambilan keputusan hingga level operasional yang terlibat dalam pelaksanaan transaksi sehari-hari, TI memainkan peran penting dalam menyediakan informasi yang diperlukan. Untuk mengoptimalkan strategi TI, diperlukan arsitektur desain yang mencakup aspek pengolahan data, komunikasi, pengelolaan data, dan sistem aplikasi utama. Keempat elemen ini saling terkait dan mempengaruhi satu sama lain. Dalam proses restrukturisasi TI, langkah-langkah yang tepat harus diambil untuk memvalidasi prinsip-prinsip yang memengaruhi parameter, skema, kebijakan, dan rencana perusahaan. Pemformulasian strategi TI tidak hanya memengaruhi pengelolaan informasi perusahaan secara keseluruhan, tetapi juga mempengaruhi arah keseluruhan manajemen bisnis. Dalam menghadapi kompleksitas lingkungan bisnis, perusahaan perlu bertransformasi dari kekuasaan ke pemberdayaan melalui TI, manajemen pengetahuan, dan pembelajaran organisasi. Pembelajaran organisasi menjadi kunci dalam adaptasi terhadap lingkungan yang dinamis dan kompleks.Pemimpin bisnis masa depan harus mampu mengelola elemen-elemen kritis seperti TI, manajemen pengetahuan, dan organisasi pembelajar. Mereka harus memiliki visi yang jelas, kekuatan horizontal, dan kemampuan untuk mengelola aset pengetahuan perusahaan. Dengan demikian, mereka dapat memastikan pertumbuhan perusahaan yang kompetitif dan inovatif dalam arena persaingan global.
A STUDY ON ELLIPTIC CURVE, ITS PROPERTIES AND APPLICATIONS
Authors: Upadhyay Bipin Chandra , Sirola Priyanka
Published: May 2024

Elliptic curve cryptography (ECC) is a kind of public key cryptosystem. In this paper, we will present some ECC algorithms and also give mathematical explanations on the working of these algorithms. Also we will discuss Elliptic curve in its application in digital signature generation and verification so as to securely transmit the data across different users.
STABILIZATION OF ANTACID FORMULATION WITHOUT SORBITOL.
Authors: Goel Achhrish , Goel Dr. Himani
Published: May 2024

The aim of present study was to develop Stabilized Antacid formulation without using sorbitol base. Sedimentation, Redispersibility and caking were the major problem in the stabilization of the antacid formulation. It was very challenging to achieve Antacid formulation without using sorbitol. This challenge achieved by taking nine different (F1-F9) trails batches using Sodium alginate and Xanthan Gum (G). Formulation (F9) obtained from the above trail batches were selected on the basis of three months accelerated stability data.
DESIGN, DEVELOPMENT AND SIMULATION OF LOW COST AUTOMATION FOR SPECIAL PURPOSE TURNING MACHINE
Authors: Pattanayak Satyajit , Bensingh R. Joseph
Published: May 2024

The project has been carried out at Rane Engine Valve Ltd. (REVL), Chennai. The main aim of the project is to design, development and simulation of Low Cost Automation (LCA) for Special Purpose Turning Machine, which is now a major area of research. The machine is a SPM and is useful for machining (undercut, turning head diameter, fillet, chamfering) operations of engine valves used in automobile industry. The objective is to reduce rejections and cost, maintain quality and to achieve high volume production. 
The methodology of design, development and simulation of Low Cost Automation for the twin spindle special purpose turning machine involves collection of data regarding pneumatic, electro pneumatic and low cost automation, enhanced concept design anddevelopment of various component of automation, electro pneumatic circuit design and simulation using Fluid SIM software. The design is based on LCA principles rather than pneumatic and PLC principles. A 3D model of the machine is also created using Pro-Esoftware to represent implemented components after the design and development process.
Mathematical Approach to Assess Phytoremediation Potential of Water Hyacinth (E Crassipes) For Distillery Effuent-A Case Study
Authors: Bhasin S.K. , Bhardwaj Punit
Published: May 2024

The Phytoremediation of distillery effluent employing water hyacinth as a phytoremediator has been assessed in terms of reduction in pH, EC,BOD, COD, TSS, TDS, Na and K. the effluent has been treated for 60 days. A significant reduction in all the selected parameters of distillery effluent over zero day value has been observed. A model for studying the phytoremediation potential of water hyacinth (E.crassipes,) against distillery effluent has been developed and analyzed. All parameters exhibited exponential decrease from the start up to 45 days and thereafter showed negligible decrease till the termination of the experiment. The value of absorption coefficient (µ) calculated from the observed as well as estimated values of all parameters have been found comparable. The proposed phytoremediation model establishes that this technique can be profitably employed for the abatement of pollution from industrial waste water.
ENHANCEMENT OF CUSTOMER SATISFACTION BY QFD IN METRO-TAXI SERVICE
Authors: Bahekar Amit , Shukla Om Prakash , Vijayvergiya Jaya
Published: May 2024

Quality must be designed in to the product, not inspected into it. In order to build a quality product, customers’ requirements have to be considered and incorporated in to the product.  Quality Function Deployment (QFD) is a tool for bringing the voice of the customer into the product development process from conceptual design through to manufacturing. It begins with a matrix that links customer requirements (CRs) to technical requirements (TRs), along with competitive benchmarking information, and further matrices can be used to ultimately link this to design of manufacturing system. Public transport system plays an important role in any city as thousands of people depend on it for their transportation in the city. Over the past few decades, cities have been growing at a tremendous pace in every aspect, including the public transport services. This paper is restricted to the discussion of “how to gain the passenger satisfaction” of the most popular type of public transport system namely the metropolitan taxi service through QFD.
NGHIÊN CỨU TẠO RỄ TƠ IN VITRO CÂY THÀNH NGẠNH (Cratoxylum pruniflorum Kurz) THÔNG QUA VI KHUẨN Agrobacterium rhizogenes
Authors: Huy Nguyễn Trần Phước , Quyên Trần Nguyễn Lệ , Trinh Cao Huệ , Quỳnh Phan Diễm , Loan Hà Thị , Quân Nguyễn Đăng
Published: May 2024

Thành ngạnh (Cratoxylum pruniflorum Kurz) thuộc loài cây mọc hoang dại và phổ biến khắp các vùng trên lãnh thổ nước ta, đặc biệt ở các tỉnh miền núi phía Bắc. Chúng được sử dụng để làm thuốc và nước uống khá phổ biến trong phạm vi dân gian. Gần đây các nhà khoa học phát hiện trong dịch chiết của thành ngạnh có chứa nhiều hợp chất có hoạt tính sinh học như các xanthone trong vỏ và rễ cây, các epigallocatechin gallate và epicatechin gallate trong lá, ngoài ra còn có các tannin, terpenoids và saponins, v.v. có hoạt tính kháng khuẩn, kháng oxy hoá và hoạt tính gây độc đối với các dòng tế bào ung thư. Trong nghiên cứu này, cuống lá in vitro cây thành ngạnh được chuyển gen hình thành rễ tơ thông qua vi khuẩn Agrobacterium rhizogenes ATCC 15834 với mật độ vi khuẩn 4.104 CFU/mL trong điều kiện bổ sung 100 µM acetosyringone. Thời gian đồng nuôi cấy trong 72 giờ cho tỷ lệ hình thành rễ tơ cao nhất đạt 4,66% trên môi trường SH không bổ sung chất điều hoà sinh trưởng. Hai dòng rễ tơ R1 và R2 được chọn lọc thông qua kỹ thuật PCR, trong đó dòng R2 tăng trưởng tốt trên môi trường lỏng SH với khối lượng tươi đạt 582,08 mg, tăng 2,19 lần so với khối lượng ban đầu nuôi cấy. Kết quả trên là cơ sở cho những nghiên cứu sâu hơn sau này trên cây thành ngạnh.
HOẠT TÍNH ỨC CHẾ ENZYM LIPASE VÀ CHỐNG TĂNG SINH DÒNG TẾ BÀO UNG THƯ VÚ MCF-7 CỦA CHIẾT XUẤT GIÀU SAPONIN, POLYPHENOL TỪ QUẢ CHUỐI HỘT Musa balbisiana Colla
Authors: Huyền Nguyễn Thị Thu , Diệu Đinh Khánh , Trâm Nguyễn Huỳnh , Nhơn Hoàng Thị Ngọc
Published: May 2024

Chuối hột Musa balbisiana là một trong những loại chuối phổ biến trên thế giới và các bộ phận của nó đã được sử dụng rộng rãi trong y học. Nghiên cứu này nhằm xác định khả năng ức chế enzyme lipase và ức chế sự tăng sinh dòng tế bào ung thư vú MCF-7 của chiết xuất giàu polyphenol và saponin từ quả chuối hột M. balbisiana. Hoạt tính kháng lipase cao của dịch chiết được đánh giá thông qua xét nghiệm lipase tụy và hoạt tính chống tăng sinh dòng tế bào ung thư vú MCF-7 bằng xét nghiệm SRB. Kết quả cho thấy dịch chiết thu được có khả năng ức chế lipase và ức chế tăng sinh dòng tế bào MCF-7 với giá trị IC50 lần lượt là 48,82 ± 1,21 μg/mL và 289,5 ± 8,7 μg/mL. Điều này cho thấy chiết xuất thu được từ quả chuối hột có thể có tiềm năng được sử dụng như một tác nhân hỗ trợ giảm béo phì và ức chế sự phát triển của dòng tế bào ung thư vú.
ĐÁNH GIÁ LỢI ÍCH CỦA THÀNH VIÊN KHI THAM GIA VÀO HỢP TÁC XÃ NÔNG NGHIỆP VÀ GIẢI PHÁP TĂNG SỐ LƯỢNG THÀNH VIÊN THÔNG QUA VIỆC GIA TĂNG LỢI ÍCH CHO THÀNH VIÊN
Authors: Thúy Nguyễn Thị Diệu , Quang Lê Hữu , Hải Trần Minh , Hải Lê Thanh
Published: May 2024

Nghiên cứu nhằm đánh giá lợi ích của thành viên khi tham gia vào mô hình Hợp tác xã (HTX) nông nghiệp và đề xuất các giải pháp tăng số lượng thành viên thông qua việc gia tăng lợi ích cho thành viên. Thông qua việc thu thập tài liệu, điều tra thực tế với việc khảo sát 300 người dân là thành viên HTX nông nghiệp Tân Bình, huyện Thanh Bình, tỉnh Đồng Tháp và 12 cuộc phỏng vấn sâu lãnh đạo cũng như thành viên của HTX. Các số liệu thu thập được xử lý bằng phần mềm thống kê mô tả SPSS, kết quả nghiên cứu đã chỉ ra những lý do chính mà người dân tham gia vào HTX là: Mua được vật tư giá thấp (91,3%), Cải thiện được điều kiện sản xuất, làm việc (85,7%) và mục đích để sử dụng các dịch vụ của HTX (79%), ngoài ra còn có các lý do khác như giảm chi phí sản xuất, nâng cao chất lượng nông sản… Đánh giá về lợi ích khi tham gia vào HTX, kết quả các thành viên cho rằng các lợi ích mà họ nhận được gồm: (1) Sử dụng các dịch vụ để phục vụ hoạt động sản xuất ; (2) Cải thiện thu nhập cho người dân; (3) Tham gia tập huấn, nâng cao trình độ, kỹ năng trong hoạt động sản xuất. Đây chính là những yếu tố cần thiết để HTX tập trung duy trì, phát triển, nâng cao lợi ích, đảm bảo nâng cao thu nhập cho thành viên từ đó có cơ sở để vận động, tuyên truyền cho người dân tham gia HTX.
Alkitab Sebagai Teks Suci Yang Tertulis
Authors: Edy Pangangkat
Published: May 2024

This research aims to analyze the strength of a religion's teaching, especially Christianity, which is taught and spread using the guidance of sacred texts or the Bible. Despite using the written tradition, there are often still various kinds of teaching, even though they come from the same source of writing. This research was conducted using a qualitative method with references or literature related to the research topic. The results obtained show that the possibility of changes in religious teaching based on written tradition is quite small when compared to religious teaching based on oral tradition. It's just that the interpretation of each reader will vary. The context and conditions of the text at the time it was written are very much different from the current conditions, when the reader learns it. Therefore, a comprehensive study of the text is needed with the appropriate hermeneutic method. Texts written in the past can still be applied in the present context, with scientific and responsible interpretation. The canonized Bible is a strong enough source for the basis of Christian teaching, especially since it was written by different people and at different times, but can be interrelated and connected to one another. 
Penelitian ini bertujuan untuk menganalisis kekuatan pengajaran suatu agama, terutama agama Kristen, yang diajarkan dan disebarkan dengan menggunakan pedoman teks suci atau Alkitab. Meskipun menggunakan tradisi tulisan, seringkali masih didapati berbagai macam pengajaran, padahal berasal dari sumber tulisan yang sama. Penelitian ini dilakukan dengan menggunakan metode kualitatif dengan referensi atau literatur yang berkaitan dengan bahasan penelitian. Hasil penelitian yang didapatkan bahwa kemungkinan perubahan pengajaran agama dengan dasar tradisi tertulis cukup kecil jika dibandingkan dengan pengajaran agama yang memiliki dasar tradisi lisan. Hanya saja interpretasi dari masing-masing pembaca akan berbeda-beda. Konteks dan kondisi teks pada saat ditulis sangat jauh berbeda dengan kondisi pada saat ini, ketika pembaca mempelajarinya. Karena itu diperlukan kajian teks yang komprehensif dengan metode hermeneutik yang sesuai. Teks yang ditulis pada masa lampau masih bisa diterapkan dalam konteks masa sekarang, dengan intepretasi yang ilmiah dan bertanggungjawab. Alkitab yang sudah terkanonisasi menjadi sumber yang cukup kuat bagi dasar pengajaran Kristen, apalagi Alkitab ditulis oleh orang yang berbeda dan di waktu yang berbeda pula, tetapi bisa saling berkaitan dan tersambung satu dengan yang lain.
Teori Falsifikasi Karl Popper
Authors: Patrika Embun Sari Winda
Published: May 2024

Why is truth always debated? Why should there be right and wrong? Why must there be black when white is so much more pleasant? Everyone has their own definition of truth. But is what is thought and meant by truth really the truth? Who determines the truth? What is the real meaning of truth? It goes back to each person or individual. What is the purpose of seeking the truth? This question could have the same element, why are humans not just happy, why do humans also have to experience sadness? Humans cannot recognise happiness if there is no sadness. Moreover, a truth that is held by Christians is Scripture, as the absolute. Religion also often feels that it is perfect, that it is the element of the world. However, all these perspectives need to be "wait and see", they need to be doubted, as Popper put it. This paper will look at Popper's critical understanding of epistemology. Then it will look at religion from Popper's perspective. He is a person who criticises the logic of knowledge. Even for him, criticism is used as a method to find a truth.
Mengapa kebenaran selalu diperdebatkan? Mengapa harus ada yang benar dan ada yang salah? Mengapa harus ada hitam bila putih jauh lebih menyenangkan? Setiap orang memiliki definisinya sendiri tentang kebenaran. Tetapi apakah yang dipikirkan dan dimaksudkan dengan kebenaran itu adalah sungguh sebuah kebenaran? Siapa penentu kebenaran? Apa makna kebenaran sesungguhnya? Kembali lagi kepada personal atau individu masing-masing. Untuk apa dicari sebuah kebenaran? Pertanyaan ini bisa saja memiliki unsur yang sama, mengapa manusia tidak bahagia saja, mengapa manusia juga harus mengalami kesedihan? Manusia tidak bisa mengenal yang namanya kebahagiaan jika tidak ada kesedihan. Terlebih lagi suatu kebenaran yang dipegang oleh Kristen adalah Kitab Suci, sebagai yang absolut. Agama juga seringkali merasa dirinya sempurna, merasa dirinya adalah unsur dunia. Akan tetapi, semua perspektif ini harus “tunggu dulu”, perlu diragukan dulu segala sesuatunya, demikian Popper katakan. Tulisan ini mau melihat pemahaman seorang Popper yang kritis terhadap epistemologi. Kemudian akan melihat agama dari kacamata Popper. Ia adalah orang yang memberi kritik terhadap logika pengetahuan. Bahkan baginya kritik digunakan menjadi metode untuk menemukan sebuah kebenaran.
Legal basis for the territorial organization of public authority in Argentina
Authors: Komlev Evgeny
Published: May 2024

The article examines the approach of the Argentine legislator to determining the legal foundations of the territorial organization of public authority. The work analyzes the norms of the Argentine Constitution, the legislation of the constituent entities of the federation (provinces), materials of law enforcement practice and doctrinal sources. The types of public territorial entities in Argentina, the sources of legal regulation of their status, the influence of the peculiarities of the historical development of the Argentine state on modern approaches to the territorial organization of public authority are explored. Taking into account the federal nature of the Argentine state, the lack of comprehensive studies of the issue of territorial organization of public authority in Argentina, the experience of the studied country seems worthy of attention within the framework of the Russian science of municipal law. It has been established that Argentine legislation provides for the existence of obligatory and optional territorial entities whose status is distinguished, first of all, by the granting of political autonomy to the former. A special feature is the provision of exclusive competence to the provinces in terms of regulating the territorial and other foundations of the organization of municipal authority. When creating municipal territorial entities, provinces establish criteria for the formation of municipalities and also provide for their division into categories. The legal status of municipalities, depending on their classification into one category or another, may differ significantly, especially in terms of the existence of institutional autonomy. The experience of Argentina can be taken into account in the context of reforming the institution of local self-government in Russia.
Direct democracy “ad hoc”: on the question of extraordinary forms of direct people’s rule
Authors: Ubasev Viktor Vladimirovich
Published: May 2024

The possibility of classifying the institutions of direct democracy as “ad hoc” legislation, that is, institutions that are extraordinary forms of direct expression of the will of the people, is being considered. The criteria for distinguishing such forms of direct democracy from forms that are of an ordinary nature, that is, designed for repeated use, are determined. The question of the advantages of forms of direct expression of the will of the people, classified as “ad hoc” legislation, over ordinary forms is explored. The article also raises the question of the risks that can be realized when using special institutions of direct democracy to solve specific problems. The relevance and novelty of the study are due to the small number of scientific works devoted to this topic - on the one hand, and the growing practical interest in the application of institutions of constitutional law related to “ad hoc” legislation in the implementation of direct democracy - on the other. At the moment, there are studies on the topics considered, carried out within the framework of the scientific subject of the theory of state and law, as discussed in the article. At the same time, there are simply no substantive constitutional and legal studies. For a long time, the answer to the question of the effectiveness of such institutions remains unclear. Conclusions: the only objective criterion that allows one to classify a particular institution or norm as an “ad hoc” norm is an indication of its one-time application of a rule of law; It seems incorrect to attribute a particular norm/institution to “ad hoc” legislation only because the law was adopted “for a specific task”; extraordinary forms of direct democracy are the most effective for conducting various kinds of electoral events, that is, voting.
Design Literacy in Chilean Curricula
Authors: Bravo Úrsula , Bohemia Erik , Saval Fernanda
Published: May 2024

The Chilean school curriculum shares with the design literacy approach the goal of forming responsible citizens committed to caring for the environment. Given that design is included as obligatory content of the visual arts and technology subjects in the first 10 years of compulsory education, we wonder if the learning objectives of visual arts and technology support the development of design literacy abilities, as outlined by Lutnæs and Cross. To address this question, we coded 119 learning objectives in alignment with Lutnæs’s and Cross’s design literacy abilities. Then, we generated heatmaps to undertake a visual analysis of the alignment between the learning objectives and design literacy categories. As a result, we found a strong convergence between the Cross and Lutnæs categories and technology learning objectives, especially in lower secondary level education. In the visual arts, design was focused on aesthetics, and connections with design literacy narratives were scarce. We propose that adopting the analytical instrument (coding table) as a standardised tool will encourage comparable studies of how well design literacy is incorporated into other national curricula.
Mecanosensibilidad en linfocitos B: rol en la dinámica y funcionalidad de lisosomas durante la sinapsis inmunológica
Authors:   , Valle Batalla Felipe Andrés del
Published: May 2024

El estudio de la mecanosensibilidad celular representa una rama de la biología que recientemente ha ganado mucho interés, reflejado en el premio Nobel de fisiología y medicina de 2021 otorgado a Ardem Patapoutian por el descubrimiento y caracterización del mecano-receptor PIEZO1. Sin embargo, poco se ha estudiado sobre cómo las señales mecánicas provenientes del entorno extracelular pueden dictar el funcionamiento del sistema inmune, y en particular, de los linfocitos B: las únicas células capaces de producir anticuerpos. En este trabajo se estudió cómo las propiedades físicas de la superficie presentadora de antígenos influyen en la capacidad de las células B para extraer antígenos inmovilizados y cómo estos procesos están conectados. Se encontró que, al interactuar con sustratos más rígidos, las células B experimentan respuestas de estiramiento celular aumentadas y mayor acetilación de tubulina, específicamente en el centro de la sinapsis inmunológica. En sustratos rígidos, los lisosomas se ubican en el centro de la sinapsis, lo que reduce su movilidad en comparación con sustratos más blandos. Los lisosomas además muestran una preferencia por asociarse con tubulina acetilada en contextos de mayor rigidez. Mecanísticamente, esto implica la translocación de ATAT1, una enzima acetilasa de microtúbulos, del núcleo al citoplasma de las células B, actuando como señal mecánica durante la estimulación del BCR. El silenciamiento de ATAT1 en células B disminuye su capacidad para estabilizar los lisosomas en la interfaz sináptica, lo que resulta en una extracción y presentación reducidas de antígenos inmovilizados a las células T. Estos hallazgos sugieren una vía que conecta la extracción de antígenos con señales mecánicas provenientes de células presentadoras de antígenos. En resumen, esta investigación aporta nuevos conocimientos y ofrece una base para comprender mejor las respuestas inmunológicas, con posibles implicaciones en terapias y trastornos inmunológicos.
Characterization of metabolic interactions mediated by human milk oligosaccharides for the identification of key species in the infant gut microbiome
Authors:   , Díaz Guerra Romina Giselle
Published: May 2024

Los infantes alimentados con leche materna poseen un microbioma intestinal generalmente dominado por especies de Bifidobacterium, con contribuciones de enterobacterias, cepas de Bacteroides y bacterias lácticas. Esta dominancia se explica en gran parte por los oligosacáridos de leche materna (HMO). Las interacciones metabólicas de las especies de Bifidobacterium con otros microorganismos intestinales son esenciales para el ensamblaje del microbioma, ya que estimulan el desarrollo inmunitario y previenen la colonización de patógenos. Sin embargo, no se ha prestado suficiente atención a cómo microorganismos de esta comunidad son capaces de cooperar o competir durante la utilización de carbohidratos complejos como lo son los HMO. El objetivo general de este trabajo será determinar interacciones metabólicas entre microorganismos representativos del microbioma intestinal infantil, mediadas por oligosacáridos de leche materna, para identificar microorganismos clave en la función metabólica de la comunidad. Como objetivos específicos se plantean 1) definir y caracterizar mediante genómica comparativa un consorcio de microorganismos aislados del microbioma intestinal humano; 2) determinar interacciones metabólicas unidireccionales y bidireccionales de microorganismos del microbioma intestinal infantil, durante la utilización de oligosacáridos de leche materna; 3) identificar especies clave en un consorcio de microorganismos para el consumo de HMO, mediante un estudio de deleción de especies en un biorreactor batch. Para alcanzar estos objetivos, contaremos con un set de microorganismos obtenidos de colección o aislados de recién nacidos, incluyendo los géneros Bifidobacterium, Streptococcus, Enterococcus, Lachnoclostridium y Bacteroides. Mediante estudios de cultivo en condiciones anaeróbicas in vitro, se estudiará cómo estas especies interactúan metabólicamente durante el consumo de HMO. Además, se realizará un estudio de deleción de especies para identificar microorganismos clave en el consumo de HMO. Esto permitirá identificar cuáles de ellos son críticos para la abundancia de especies, la utilización de HMO y la producción de metabolitos. Este trabajo aportará conocimiento en la identificación de interacciones metabólicas entre microorganismos del microbioma intestinal infantil. Además, podremos identificar especies clave de un consorcio en el consumo de HMO con el fin de desarrollar consorcios microbianos con propiedades terapéuticas en los recién nacidos.
Governança e gestão de pessoas na administração pública: avanços para a gestão de pessoas
Authors: Gaia Adriane Rodrigues , Silva Christian Luiz da
Published: May 2024

A governança e a gestão de pessoas na administração pública têm se destacado como áreas cruciais na promoção da eficiência e a responsabilidade das instituições governamentais. Nos últimos anos, tem-se observado um movimento crescente em direção a práticas mais transparentes e participativas, impulsionado pela necessidade de responder às demandas cada vez mais complexas da sociedade. Esse avanço inclui a adoção de sistemas de avaliação de desempenho mais rigorosos, o fortalecimento de mecanismos de prestação de contas e a promoção de uma cultura organizacional que valorize a meritocracia e a inovação. Assim, o objetivo geral desta pesquisa é analisar e compreender as práticas de governança e gestão de pessoas na administração pública, buscando identificar os principais avanços, desafios e perspectivas nesses campos. De modo que, através de uma revisão da literatura esta pesquisa, apresenta uma série de direcionamentos importantes sobre o estado atual e as perspectivas futuras desses campos. Os recentes avanços evidenciam uma forte tendência em direção a práticas mais transparentes, participativas e orientadas para resultados, que refletem um esforço contínuo na busca pela promoção da eficiência e a responsabilidade no setor público. Todavia, os desafios enfrentados, como a burocracia, a capacidade institucional e a rápida evolução tecnológica, enfatizam a necessidade de uma abordagem holística e adaptativa para abordar essas questões complexas.
Marketing sensorial aliado a semiótica para criação de marcas
Authors: Canivello Nathalia Avila
Published: May 2024

Com a disseminação global da informação, as marcas enfrentam o desafio de diferenciar-se para atrair os consumidores. Para alcançar esse objetivo, é essencial estabelecer uma conexão significativa entre os elementos simbólicos das marcas e os consumidores. Nesse sentido, as marcas devem entender os desejos de cada segmento de consumidores que desejam alcançar, não apenas sendo atraentes, mas também redefinindo suas percepções aos olhos do cliente. A escolha e a combinação cuidadosa de palavras, imagens, aromas e sabores podem tornar o desejo de consumo mais atrativo em sua apresentação, ampliando seu poder persuasivo. A interação entre o neuromarketing e o marketing sensorial desempenha um papel crucial na compreensão dos processos de desejo do consumidor. A adoção de estratégias que empregam ferramentas como a semiótica pode fortalecer e tornar as marcas mais memoráveis para os consumidores. Essa abordagem visa construir laços emocionais duradouros entre as marcas e seu público-alvo, elevando sua relevância e distinção no mercado global.
Novel Mathematical Models for Prediction of Spent Engine oil Interactions with Vernonia amygdalina Leaf Extract
Authors: Ntesat Unyeawaji Brownson , Achinike Okogbule-Wonodi , Emeka Chinwendu , Zacchaeus Mgbowaji
Published: May 2024

Aims: The michaelis-menten biokinetic model was used for the determination of key biokinetic parameters; maximum specific rate constant ( and michaelis-menten constant ( including  the total polycyclic aromatic hydrocarbon (TPAH) degradation rate equation in the biostimulation of spent engine oil (SEO) – contaminated soil  using vernonia amygdalina leaf (bitter leaf) extract.
Study Design:  Single factor experiment in a randomized complete block design (RCBD) was used in this study.
Place and Duration of Study: Research farm, Rivers state university, Port-Harcourt, Nigeria, between April 2023 and May 2023.
Methodology: TPAH was quantified by the standard method, according to USEPA method using gas chromatography-mass spectrometry (GC-MS). The experiment consisted of 4 reactors replicated thrice including the control (Labelled A to D) comprised of soil, SEO and bitter leaf extract in the ratios of 8:1:0.5, 8:1:1, 8:1:1.5, and 8:1:0, respectively, after 8 weeks of treatment.
Results: The results obtained shows that TPAH concentration dropped by 42.3 – 63.9% from 98.73mg/kg-1 with an average reduction of 52% was achieved in all treatment reactors. The average of   was 4.4mg/kg-week and   was 79.2mg/kg while the TPAH degradation was deduced as  at any TPAH concentration. The validation of the developed model indicates a high coefficient of determination (2) ranging from 0.927 to 0.992 and a low root mean square error of 9.08 to 20.81mg/kg. This statistical tool effectively shows the potential of the model to predict TPAH concentration in the biostimulation of spent engine oil-polluted soil using bitter leaf extract
Conclusion: Up to 63.9% TPAH reduction was achieved for the stated period. The evaluation results show the potential of the model to predict TPAH in the biostimulation of SEO–contaminated sandy loam soil using bitter leaf extract.
Diversity and Abundance of Wetland Birds in Udayamarthandapuram Bird Sanctuary, Tiruvarur District, Tamil Nadu, India
Authors: N Satheesh , Baranidharan K. , Krishnamoorthi S. , Vijayabhama M. , Mugilan S.
Published: May 2024

Wetland birds are integral components of wetland ecosystems, providing ecological, economic, cultural, and regulatory benefits. The study conducted from 2021 to 2024 in the Udayamarthandapuram Bird Sanctuary of Tiruvarur district aimed to assess year-wise species diversity, richness, relative diversity, evenness, density, and relative abundance of wetland birds employing the total count method to estimate the population of wetland birds. A total of 104 bird species belonging 18 orders and 49 families were recorded. During this study, 17 species were migrant, while the remaining 87 birds were resident. Three bird species were classified as Near Threatened, including the Spot-billed Pelican (Pelecanus philippensis), Black-headed Ibis (Threskiornis melanosephalus), and Oriental Darter (Anhinga melanogaster). Additionally, two bird species were classified as Vulnerable, namely the Greater Spotted Eagle (Clanga clanga) and River Tern (Sterna hirundo), while 99 bird species were classified as Least Concern. Regarding species diversity in the Udayamarthandapuram Bird Sanctuary during different years, the highest species diversity was recorded in 2021 (2.75), while the lowest species diversity was observed in 2024 (1.64). In terms of species richness, the maximum richness was observed in 2023 (68), whereas the minimum species richness was recorded in 2022 (29).
Examining Conflict Management Strategies Used in Tanzania’s Secondary Schools: A Case in Biharamulo District, Tanzania
Authors: Khalid Hamud , Qian Xu
Published: May 2024

The study delves into the pervasive issue of conflicts within secondary schools, emphasizing their inherent nature in human interactions. It emphasizes the vital role of effective conflict management in maintaining a conducive learning environment. The research objectives cover the identification of conflict root causes, assessment of implemented strategies, and their impacts, and provision of recommendations for improved conflict management approaches in schools. Employing qualitative methodology, the study utilizes in-depth interviews, group discussions, and document reviews to collect data. Findings reveal the persistence of conflicts, notably attributed to the lack of a universally accepted resolution framework. Ad hoc methods are employed, lacking consistency and alignment with specific conflict natures, resulting in profound consequences such as student dropout, prolonged conflicts, fear, resentment, and hindered academic progress. The study recommends government intervention in training teachers, rigorous evaluation of school administrators' qualifications, and improvements in teacher welfare coupled with strict punitive measures for teachers’ inappropriate behavior. It concludes by highlighting the ongoing nature of conflicts and the urgent need for a practical approach, urging schools to prioritize understanding conflict causes, implementing effective management actions, and prioritizing the well-being of both teachers and students.
Synthesis and Crystal Structure Studies of a New Complex of Co (III)-Schiff Base Derivative Derived from Isonicotinohydrazide
Authors: Diop Babacar , Seck Thierno Moussa , Ndoye Cheikh , Thiam Ibrahima El-hadji , Diouf Ousmane , Tamboura Farba Bouyagui , Retailleau Pascal , Gaye Mohamed
Published: May 2024

A new Co(III) complex prepared by the reaction of N'–(1–(pyridin–2 yl)ethylidene) isonicotinohydrazide (H2L) with Co(II) ion is reported in this paper. The H2L ligand is structurally characterized by elemental analysis, NMR, and infrared spectroscopies. The mononuclear complex [Co(HL)2]·Cl·3H2O (1), is characterized by infrared spectroscopy, elemental analysis, conductance, magnetic room temperature measurement and single X-ray diffraction. The complex crystallizes in the monoclinic system with space group P21/c. The parameters of the unit cell are a = 9.6818(3) Å; b = 25.1587(6) Å; c = 11.5481(3) Å;   β = 101.797(3) °; Z = 4; Rint = 0.0313 and wR(F2) = 0.0812. The asymmetric unit of the compound contains a discrete [Co(HL)2]+ cation one  free chloride anion and three uncoordinated water molecules. In the discrete cation one Co3+ ion two organic ligand molecules are present. The coordination polyhedron around the Co3+ center is best described as a distorted octahedral with CoN4O2 chromophore. The crystal structure of the complex is stabilized by intramolecular and intermolecular hydrogen bonds.
Gas Chromatography Based Analysis of Fatty Acid Profiles in Poultry Byproduct-Based Pet Foods: Implications for Nutritional Quality and Health Optimization
Authors: Kumar Rishav , Goswami Meena , Pathak Vikas
Published: May 2024

The nutritional quality of pet foods plays a crucial role in maintaining the health and well-being of companion animals. In this study, we investigated the fatty acid compositions of various pet foods, including chicken powder, poultry byproducts incorporated vegetables, byproducts incorporated with ragi, and boiled mash Potato, to assess their scientific significance and potential implications for pet nutrition. Our analysis revealed diverse fatty acid profiles across the different pet foods, with each food exhibiting unique compositions and proportions of fatty acids. Notable findings include the identification of common fatty acids shared among multiple pet foods, as well as variations in the abundance of specific fatty acids across different formulations. Additionally, certain pet foods are characterized by the presence of rare or unusual fatty acids, highlighting the importance of exploring their sources and potential health benefits. By correlating the fatty acid compositions of pet foods with metabolic pathways and health implications, we elucidated the nutritional significance of these dietary components for pets. Furthermore, we identified areas for further research, including the impact of processing methods on fatty acid profiles and the development of novel formulations optimized for pet nutrition and well-being. Overall, this study contributes valuable insights into the scientific understanding of pet nutrition and underscores the importance of considering fatty acid compositions in formulating balanced and nutritious diets for companion animals.
Role of Epigenetics in Cancer and Targeted Therapies for Oncologic Treatments
Authors: Srinivas Martha , Sanjay Salunkhe Pratiksha , Manik Londhe Pratima , Babar Vishal Bharat , Maheshwari Koppula
Published: May 2024

DNA sequence has little bearing on the dynamic and heritable changes to the genome that occur in epigenetics. Both genetic and epigenetic alterations influence the development of cancer. There are several opportunities for therapeutic interventions because epigenetic modifications can be reversed. Many epigenetic drugs are currently used globally to treat conditions including leukemia and myelodysplastic syndrome. Owing to their malleability and vulnerability to outside factors, epigenetic modifiers are becoming intriguing targets for a number of cancer treatments. Recently, a large number of epi-drugs have been developed, and they may find application in clinical situations. The aforementioned initiatives to realize the potential of epigenetic medicines for efficient cancer treatment are summed up in this review. The maintenance of cell identity and the spatial and temporal regulation of gene expression depend on the proper coordination of epigenetic regulators. Both genetic and epigenetic changes contribute to cancer. The development of medications that target epigenetic regulators has advanced significantly over the past few decades, with numerous medications currently under assessment in research studies. In how they could be used to treat cancer. We also go over the preclinical and clinical outcomes of epigenetic medication combination therapies as well as other therapies including immune-based and targeted medicines.
Weeds and Their Response to Changing Climate: A Review
Authors: Umkulzhum Fathima , M. Ameena , V. S. Susha , B Renjan , K Sreelekshmi , V. S. Sethulekshmi , Shanavas Shifina
Published: May 2024

Climate change is one of the most important parameters to cause alteration in weed composition, population growth, life processes, physiological development, and infestation pressure. A few of the weed species may become inactive, while the rest may become aggressive invaders. Weeds possess unique biological characteristics and ecological range that enable them to tolerate and successfully intrude in any ecosystem with varied environmental conditions. Rising carbon dioxide, will benefit C3 crops to expand their photosynthetic capacity, thus leading to increased biomass production and productivity, on the other hand increased temperatures will benefit the C4 crops. These differences in response of C3 and C4 crops to changing climate will influence crop-weed interaction, most likely at the expense of crop. Moisture is another important environmental factor which plays a major role in weed seed germination, thus the survival. Temperature and relative humidity influence the course of absorption, translocation, and metabolism of herbicides in plants, any change in their range leads to decreased herbicide efficacy and thus the weed control. Studies focussed on the performance of weeds under elevated environmental factors help to make strategic decisions on their management before having their impact on change in weed biological aspects, and foresee the future with elevated temperature and carbon dioxide conditions. Weeds such as Parthenium hysterophorus, Sphagneticola trilobata, Prosopis juliflora and Eichhornia crassipes, have been identified as potential future threats. Consequently, exploring the bioprospecting potential of these weeds is seen as an inevitable necessity.
Assessment of Soil Erosion within the Gayathripuzha River Basin Using RUSLE Model and GIS Tools
Authors: Bai E.B. Gilsha , Raju Ardra , Rema K.P. , Sumiya K V , Varughese Anu , Resmi J
Published: May 2024

Soil erosion, a natural phenomenon accelerated by human activities, became a major problem for agricultural land use and for water quality concerns. Soil erosion by water is influenced by various factors like climate, nature of land surface, slope steepness, soil properties, land cover, and management practices.  Estimation of soil erosion is essential to know the nature and quantity of soil loss and create specific strategies for soil conservation. This research paper thoroughly examines the susceptibility of soil erosion in the Gayathripuzha river basin in Kerala, India, which is encompassing a wide area of around 961 km².  Employing the Revised Universal Soil Loss Equation (RUSLE), this investigation assesses the influential factors affecting soil erosion, which comprise rainfall (R Factor), soil erodibility (K Factor), topography (LS Factor), land usage (C Factor), and the impact of conservation measures (P Factor).  The study was conducted using Geographic Information System (GIS) tools like ArcGIS 10.8 Desktop and integrating data on rainfall, soil properties, land topographic features, and land use.  Rainfall erosivity is a major factor causing erosion in Gayathripuzha river basin and it ranges from 746.03 to 1222.35 MJ mm ha−1 h−1 y−1 in the river basin. Soil erodibility factor also varies widely within the region.  Slope length and steepness factor showed that highland ecosystems are present only in a small area of the river basin.  Variation in land use and land cover also influenced the soil erosion within the area. The estimated average annual soil erosion ranges from 0 to 133.18 t ha-1 yr-1 within the research site. The research found that soil erosion varied greatly across the study area. Regions with slopes over 50% had much higher erosion rates, while most of the study area had low erosion levels. Notably, the intensity of soil erosion demonstrated a positive correlation with slope percentage, with areas classified as bare ground demonstrating the highest erosion rates. These findings emphasize the necessity for targeted and comprehensive conservation strategies tailored to the diverse landscape of the region to effectively manage soil erosion and mitigate its adverse impacts.