bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of a synthetic analog of prostaglandin F2a-cloprostenol after foaling
Authors: Солодова Елена Владимировна
Published: July 2024

В статье приведены результаты опыта по применению эстрофантина (синтетического аналога простагландина F2a - D-клопростенола) в виде курса внутримышечных инъекций после выжеребки. Показано, что у 60% (6 из 10) кобыл опытной группы первая овуляция происходила в среднем на 7 дней позже, чем у кобыл контрольной группы: на 18,2±1,0 и 11,1±0,5 дни соответственно. За счёт повышения уровня зажеребляемости кобыл, жеребившихся более трёх раз, зажеребляемость кобыл в опытной группе в первую охоту была выше, чем в контрольной, на 30%, что говорит о большей целесообразности курса клопростенола после выжеребки для возрастных кобыл.

In article results of experiences on the application strofantina (synthetic analogue of prostaglandin F2a - D-cloprostenol) in a course of intramuscular injections after foaling are given. It was shown that 60% (6 out of 10) of mares in the experimental group had their first ovulation on average 7 days later than in the control group: 18.2±1.0 and 11.1±0.5 days, respectively. Due to the increase in the level of foaling of mares foaled more than three times, the foaling of mares in the experimental group in the first hunt was higher than in the control group, by 30%, which indicates a greater expediency of the course of cloprostenol after foaling for old mares.
Formation of Chetkiy line with the phenomenon of curly hair in the zabaikalskaya breed
Authors: Базарон Бадма Зилимович , Калашников Родион Валерьевич , Хамируев Тимур Николаевич , Дашинимаев Солбон Мункуевич , Шкуратова Галина Михайловна , Храброва Людмила Александровна
Published: July 2024

В статье приведены результаты зоотехнической оценки линии Четкого - родоначальника курчавости лошадей в забайкальской породе для разработки подробной характеристики. Приводятся промеры и живая масса сыновей и внуков родоначальника линии жеребца Четкого. Исследования проводились в СПК им. Калинина Агинского района Забайкальского края.

This article provides a study of Chetkiy line -the ancestor of curly-haired horses of the Zabaikalskaya breed to develop detailed characteristics. The measurements and live weight of sons and grandsons of Chetkiy are given. Studies were conducted in the breeding farm named Kalinin, Aginsk region, Trans-Baikal Territory.
Application of the IRS “KONI-3” for the analysis of the results of horses of Trotting breeds at the racetracks of the Ural Federal district
Authors: Дубровин Александр Витальевич , Левина Ирина Сергеевна
Published: July 2024

Статья посвящена исследованию результатов испытаний лошадей рысистых пород на ипподромах Уральского федерального округа посредством информационно-поисковой системы «КОНИ-3». Авторами отмечена необходимость более широкого внедрения информационно-цифровых систем, которые позволяли бы максимально быстро вводить в них информацию и получать необходимые для организации и проведения селекционно-племенной работы ответы. В работе использовались общенаучные методы: абстрактно-логический, индукции и дедукции, синтеза и сравнения. Результаты исследования показали эффективность применения возможностей ИПС «КОНИ-3» для формирования по различным критериям выборок лошадей рысистых пород, проходящих ипподромные испытания. Научная новизна исследования заключается в проведённом сравнительном анализе деятельности ипподромов Курганской, Свердловской и Тюменской областей за период 2017-2019 годов.

The article is devoted to research of the results of trials of horses of Trotting breeds at the racetracks of the Ural Federal District by means of the Information Retrieval System «KONI-3». The authors noted the need for a broader introduction of information and digital systems that would allow you to quickly enter information into them and get the answers necessary for organizing and conducting breeding work. General scientific methods were used: abstract-logical, induction and deduction, synthesis and comparison. The results of the research showed the effectiveness of application of the IRS «KONI-3» for the formation of samples of horses of Trotting breeds, passing racetrack trials, according to various criteria. The scientific novelty of the research is the comparative analysis of the activities of the hippodromes of Kurgan, Sverdlovsk and Tyumen regions for the period 2017 - 2019.
New Ohizh line with phenomenon of curly hair in the Buryatskaya horse breed
Authors: Базарон Бадма Зилимович , Хамируев Тимур Николаевич , Дашинимаев Солбон Мункуевич , Будажанаев Булат Цырендоржиевич , Храброва Людмила Александровна , Зайцев Александр Михайлович , Калашников Родион Валерьевич
Published: July 2024

В данной статье представлена характеристика потомства линии Чижа - родоначальника группы курчавых лошадей в бурятской породе - по экстерьерно-конституциональным и фенотипическим особенностям. Приведены показатели промеров статей тела и живой массы сыновей, внуков, правнуков, дочерей, внучек и правнучек линии Чижа. Исследования проводились в племенном заводе сельскохозяйственного производственного кооператива «Ульдурга» Еравнинского района Республики Бурятия.

This article presents the characteristics of the offspring of Chizh line - the ancestor of the group of curly horses in the Buryatskaya breed - in terms of their exterior constitutional and phenotypic characteristics. Indicators of measurements of body weight and live weight of sons, grandchildren, great-grandchildren, daughters, granddaughters and great-granddaughters of the Chizha line are given. The research was carried out in the breeding plant of the agricultural production cooperative «Uldurga» of the Yeravninsky district of the Republic of Buryatia.
Development and current state of the shetland pony breed in kaliningrad region
Authors: Миронова Татьяна Александровна
Published: July 2024

В работе приводится история появления и развития шетлендской породы пони на территории Калининградской области, дается описание первых ввезенных в регион представителей данной породы и их потомков, уточняется линейная структура региональной популяции.

The paper describes the history of the appearance and development of the Shetland pony breed in the Kaliningrad region, the first representatives of this breed and their descendants imported into the region, and clarifies the linear structure of the regional population.
ABOUT MEAT PRODUCTIVITY OF BURYAT COLTS
Authors: Дашинимаев Солбон Мункуевич , Базарон Бадма Зилимович , Хамируев Тимур Николаевич , Калашников Родион Валерьевич , Зайцев Александр Михайлович , Будажанаев Булат Цырендоржиевич
Published: July 2024

В статье изучена мясная продуктивность молодняка бурятской породы в возрасте 6, 18 и 30 месяцев. Проведенные исследования показали, что живая масса подопытного молодняка лошадей с возрастом закономерно увеличивается.

The article studies the meat productivity of young Buryat breed at the age of 6, 18 and 30 months. Studies have shown that the live weight of the experimental young horses regularly increases with age.
THE RELEVANCE OF THE DEVELOPMENT AND IMPLEMENTATION OF ELECTRONIC DOCUMENT MANAGEMENT SYSTEM IN HORSE BREEDING
Authors: Дубровин Александр Витальевич
Published: July 2024

Современные условия труда и широкие возможности электронных коммуникаций оказывают значительное влияние на потребность в цифровом управлении данными. Сегодня каждый из нас в своей работе использует информацию различного формата: от текста и таблиц до аудио и мультимедийного содержимого. В большинстве случаев, как правило, это неструктурированные данные, что затрудняет их применение. Организации сталкиваются с проблемой нерационального расходования человеческих, материальных ресурсов и неэффективной работой при традиционной технологии ведения документооборота. С этой точки зрения система электронного документооборота (СЭД) стала прекрасным решением данной проблемы. Применение информационных технологий для управления документами позволяет организациям повышать производительность, эффективность и конкурентоспособность в условиях современного рынка. Основная цель данной работы - показать важность разработки и внедрения СЭД в отрасли коневодства России.

Current working conditions and the great possibilities of electronic communications have a significant impact on the need for digital data management. Today, each of us uses information in various formats in our work: from text and tables to audio and multimedia content. Basically, in most cases that are unstructured data, which makes it difficult to use them. In addition, organizations are faced the problem of irrational expenditure of human and material resources and inefficient work with traditional document management technology. Organizations are faced the problem of irrational expenditure of human and material resources and inefficient work at traditional document management technology. From this aspect, the electronic document management system (EDMS) has become an excellent solution to this problem. The application of information technology for document management allows organizations to increase productivity, efficiency and competitiveness in today’s market. The main aim of this work is to show the importance of developing and implementation of the EDMS in horse breeding in Russia.
APPLICATION OF GEOMETRIC MORPHOMETRY METHODS IN THE DIFFERENTIATION OF SHETLAND PONY OF DIFFERENT POPULATIONS
Authors: Купцова Надежда Александровна , Дацышин Андрей Александрович
Published: July 2024

Актуальность: опираясь на инструментарий геометрической морфометрии найти отличительные признаки между шетлендскими пони различных популяций.

Based on the tools of geometric morphometry to find the distinctive features between Shetland ponies of different populations.
ANALYSIS OF THE BREEDING USE OF THE PUREBRED ARABIAN STALLIONS IMPORTED FROM FRANCE IN 2001 - 2016
Authors: Халилов Руслан Аметович , Королева Галина Владимировна , Шемарыкин Александр Евгеньевич
Published: July 2024

В процессе работы проанализировано использование каждого импортированного жеребца-производителя, генеалогические подборы к нему, выявлены наиболее удачные сочетания, определена племенная ценность по качеству полученного приплода, проведена сравнительная оценка приплода со сверстниками по показателям селекционируемых признаков, изучено генеалогическое изменение структуры породы.

In the course of the work, the use of each imported stallion, genealogical selections for it were analyzed, the most successful combinations were identified, the breeding value was determined by the quality of the obtained offspring, a comparative assessment of the offspring with peers was carried out according to the indicators of the selected traits, the genealogical change in the structure of the breed was studied.
MECHANIZATION OF THE MAIN TECHNOLOGICAL PROCESSES IN KUMYS PRODUCTION
Authors: Матвиенко Максим Александрович , Родионова Антонина Александровна
Published: July 2024

В статье описаны основные этапы механизации технологических процессов производства кумыса. Представлены методы модернизации оборудования для производства кумыса.

The article describes the main stages of mechanization of technological processes of kumis production. Methods of modernization of equipment for the production of kumis are presented.
Analysis of the origin of horses participating in dressage competitions at the Olympic games in Tokyo 2021
Authors: Дорофеева А.В. , Политова М.А.
Published: July 2024

В статье представлена информация о породном составе и анализ происхождения лошадей, выступавших на Олимпийских играх в Токио в линейном и генеалогическом разрезе.

The article presents information about the breed composition and analysis of the origin of horses that competed at the Olympic Games in Tokyo in a linear and genealogical section.
Analysis of the suitability of existing methods for an objective assessment of the working capacity and desirable working qualities of horses of useful breeds
Authors: Журавлева Ю.Д. , Цыплакова Н.Б. , Ясинская А.А.
Published: July 2024

В статье представлен анализ применяемых в настоящее время методик оценки работоспособности лошадей разного направления использования. Отмечены их достоинства и недостатки. Рассмотрена возможность адаптации программы соревнований по конному туризму в качестве теста для оценки рабочих качеств лошадей пользовательных пород на примере вятской.

The article presents an analysis of the currently used methods for assessing the performance of horses in various fields of use. Their advantages and disadvantages are noted. The possibility of adapting the equestrian tourism competition program as a test for assessing the working qualities of horses of use breeds on the example of Vyatka is considered.
Khakasskaya horse: history, modernity and prospects of the breed
Authors: Коломеец Ю.Ю.
Published: July 2024

Хакасская лошадь - одна из самых малоизученных и красивейших аборигенных лошадей Сибири универсального направления. Она возникла в результате народной селекции под непрерывным влиянием местного климата и насчитывает более двух тысячелетий. Однако сегодня мы рискуем «растворить» бесценный генофонд в тяжеловозных помесях и навсегда потерять самобытную популяцию, по стечению обстоятельств до сих пор не внесенную в реестр аборигенных пород России. Но сейчас ещё не поздно спасти от исчезновения уникальную древнюю породу, над разведением которой коневоды работали на протяжении всей истории региона.

The Khakasskaya horse is one of the most poorly studied and most beautiful indigenous horses of Siberia of universal direction. It arose as a result of folk breeding under the continuous influence of the local climate and has more than two millennia. However, today we risk «dissolving» the priceless gene pool in Draft crossbreeds and permanently losing the original population, which by coincidence has not yet been included in the register of native breeds of Russia. But now it is not too late to save from extinction a unique ancient breed, over the breeding of which horse breeders have worked throughout the history of the region.
Breeding horse breeding in Russia - image and realities
Authors: Калашников В.В. , Зайцев А.М. , Калинкина Г.В. , Дубровин А.В. , Калашников Р.В.
Published: July 2024

Исследованы организационно-экономические, нормативные и правовые, социальные и иные специальные аспекты организации современной системы племенного коневодства в России. Сделаны экспертные заключения о динамике, тенденциях и перспективах развития инфраструктуры селекционного процесса, идентификации поголовья, организации племенного учета в разрезе пород и направлений использования лошадей, ведения племенных книг. Дополнительно рассмотрены возможные перспективы развития системы племенного коневодства в стране с учетом сложившихся типов племенных предприятий и фактической эффективности их функционирования по назначению в условиях деконцентрации производящего состава и изменения векторов селекционного давления на фенотипические признаки в современных условиях функционирования отрасли.

The organizational-economic, regulatory and legal, social and other special aspects of the organization of the modern system of breeding horse breeding in Russia are investigated. Expert conclusions were made on the dynamics, trends and prospects for the development of the infrastructure of the breeding process, the identification of livestock, the organization of breeding records in the context of breeds and areas of use of horses, the maintenance of stud books. Additionally, the possible prospects for the development of the breeding horse breeding system in the country are considered, taking into account the existing types of studs and the actual efficiency of their functioning for their intended purpose in the conditions of deconcentration of the producing composition and changes in the vectors of breeding pressure on phenotypic traits in the modern conditions of the functioning of the industry.
Negative trends in the domestic racing industry and ways to overcome them
Authors: Стольная Е.С.
Published: July 2024

Проанализирована работа тотализатора на ЦМИ с 2015 до 2021 года. Рассмотрены особенности организации и проведения скаковых сезонов в России. Выявлены негативные тенденции, появившиеся в чистокровном коннозаводстве и ипподромной индустрии России в последние годы, и предложены пути их преодоления.

The work of the national equestrian totalizator from 2015 to 2021 was analyzed. The negative trends that have appeared in the thoroughbred horse breeding and the hippodrome industry in Russia in recent years have been identified, and ways to overcome them have been proposed.
WORKING QUALITIES OF MEZEN HORSES. RESULTS OF THE XII REGIONAL COMPETITIONS
Authors: Вдовина Н.В. , Юрьева И.Б. , Поршнева Е.В.
Published: July 2024

В феврале 2022 года в г. Мезени Архангельской области прошли XII Областные соревнования конников на лошадях мезенской породы. За два дня соревнований в семи видах испытано 18 лошадей. В ходе соревнований животные самой северной в России генофондно-племенной фермы СПК РК «Север» в непростых погодных условиях Крайнего Севера подтвердили свою высокую разностороннюю работоспособность.

In February 2022, the XII Regional equestrian competitions on horses of the Mezenskaya breed were held in the town of Mezen, Arkhangelsk region. During two days of competition, 18 horses were tested in seven types. During the competition, the animals of the northernmost gene pool breeding farm in Russia of the SEC RK «North» in the difficult weather conditions of the Far North confirmed their high, versatile performance.
DECENTRALIZED BREEDING RECORDS AND ITS CONSEQUENCES FOR THOROUGHBRED BREED
Authors: СУЛЕЙМАНОВ О.И.
Published: July 2024

Изучена эволюция правил ведения племенного учета лошадей чистокровной верховой породы. После принятия Государственной племенной книги (Госплемкнига) России в состав международного комитета по племенным книгам (International Stud Book Committee - ISBC) в 1999 году, учет и регистрация лошадей с выдачей племенных свидетельств (паспортов) перешли на качественно новый уровень и соответствуют всем требованиям международных правил.Очередные тома Госплемкниги, изданные во ВНИИ коневодства на русском и английском языках, прошли рецензию со стороны кураторов из международного комитета, после чего разосланы в 70 стран мира, состоящих в указанном комитете.Запись лошади в международной Племенной книге даёт возможность участия в скачках на любом ипподроме мира, открывает допуск лошадям на мировой рынок чистокровного коневодства.В этой связи обоснована необходимость сохранения системы ведения централизованного племенного учета, которая создана во ВНИИ коневодства, и на протяжении более тридцати лет постоянно совершенствуется, доказав свою уникальность и безальтернативность.

The evolution of breeding records of Thoroughbreds has been studied. After Approval of the Russian Thoroughbred Stud Book in 1999, the registration of horses and the issuance of passports, moved to a new level and correspond to all requirements of International Rules.Volumes of the Stud Book, published at the Institute of Horse Breeding in Russian and English, were reviewed by International Stud Book Committee (ISBC) and distributed to 70 countries, that are ISBC members.Registration of a horse in the International Stud Book makes it possible to participate in races at any Racecourse in the world, opens the door to the world Thoroughbred market. In this regard, the need to preserve the system of centralized breeding records, which was created at the Institute of Horse Breeding and has been constantly improved for more than thirty years, has been substantiated, proving its uniqueness and no alternative.
مشكلات إدارة الصف التي تواجه معلمات الطفولة المبكرة
Authors: الغامدي شريفه سعد
Published: July 2024

هدفت الدراسة إلى التعرف على مشكلات إدارة الصف التي تواجه معلمات الطفولة المبكرة، واستخدمت الدراسة المنهج الوصفي التحليلي، تكونت عينة الدراسة من (55) معلمة من معلمات الطفولة المبكرة، استخدمت الدراسة أداة واحدة تمثلت في استبانة لجمع البيانات، وتوصلت نتائج الدراسة إلى: بلغ المتوسط الحسابي لاستجابة أفراد عينة الدراسة على المحور الأول: إدارة الصف المتعلقة بالمعلمة يساوي (2.61)، في حين بلغ المتوسط الحسابي لاستجابة أفراد عينة الدراسة على المحور الثاني: إدارة الصف المتعلقة بالإدارة الصفية للمعلمة يساوي (3.02)، حين بلغ المتوسط الحسابي لاستجابة أفراد عينة الدراسة على المحور الثالث: المتعلق بمشكلات إدارة الصف المتعلقة بالأطفال يساوي (2.92)، كما بلغ المتوسط الحسابي لاستجابة أفراد عينة الدراسة على المحور الرابع: المتعلق بمشكلات إدارة الصف المتعلقة بالبيئة الصفية والمدرسية يساوي (3.01)، وأيضاً بلغ المتوسط الحسابي لاستجابة أفراد عينة الدراسة على المحور الخامس: المتعلق بمشكلات إدارة الصف المتعلقة بأولياء الأمور يساوي (2.94)، كما توصلت الدراسة إلى عدم وجود فروق ذات دلالة إحصائية عند مستوى (0.05) في استجابات عينة الدراسة نحو مشكلات إدارة الصف التي تواجه معلمات الطفولة المبكرة باختلاف متغير الخبرة في التعليم والمؤهل العلمي، وأوصت الدراسة بضرورة تقليل النصاب التدريسي لمعلمات الطفولة المبكرة، ومراعاة اختلاف تخصص معلمة الطفولة المبكرة عن المواد التي تقوم بتدريسها، وعلى أن تقوم معلمة الطفولة المبكرة بتدريس عدد قليل من المواد تتناسب مع تخصصها.
Multi-objective reaction optimization under uncertainties using expected quantile improvement
Authors: Zhang Jiyizhe , Semochkina Daria , Sugisawa Naoto , Woods David , Lapkin Alexei
Published: July 2024

Multi-objective Bayesian optimization (MOBO) has shown to be a promising tool for reaction development. However, noise is usually unavoidable during experiments and makes it challenging to find reliable solutions. In this study, we focus on finding a set of optimal reaction conditions using multi-objective Euclidian expected quantile improvement (MO-E-EQI) under noisy settings. First, the performance of MO-E-EQI is evaluated by comparing with some recent MOBO algorithms \textit{in silico} with linear and log-linear heteroscedastic noise structures and different magnitudes. It is noticed that high noise can degrade the performance of MOBO algorithms. MO-E-EQI shows robust performance in terms of hypervolume-based metric, coverage metric and number of solutions on the Pareto front. Finally, MO-E-EQI is implemented in a real case to optimize an esterification reaction to achieve maximum space-time-yield and minimal E-factor. The algorithm identifies a clear trade-off between the two objectives.
A cross-sectional study of knowledge and barriers in uptake of cervical cancer screening
Authors: R Gautham Chakra , CH Pavani , S Lokeswari , G Jaya Sudha , N Sravanthi , B Govardhan
Published: July 2024

More than 90% of instances of cervical cancer in women occur in developing nations, making it the second most frequent malignancy in women globally. About 15% of cancer-related fatalities worldwide are attributed to India, primarily in rural regions. This harmful condition can be effectively prevented by developing awareness campaigns and offering early Screening as a viable management option. From January 1, 2024, to June 30, 2024, a prospective questionnaire-based survey was carried out among women. Students made up the majority of the research population. There were 340 ladies among them. The majority of the 292 women (86%) who have not attended Screening gave a variety of excuses. Of the 48 women who showed up for the test, 23 (or 47.9%) had different symptoms and were receiving treatment. Three of these individuals were found to have cervical cancer. Obstacles were noted, including a weak economy, cultural legacies, ignorance, a shortage of women in the testing facilities, etc. Pap smear testing facilities must be available to all medical professionals and primary healthcare facilities.
Efficient Adsorption of Cr(VI) from Aqueous Solutions Using Composites Modified with Ni/Al LDH and Keggin Type Compounds
Authors: Normah Normah , Adhiyanti Nurmalina , Sayeri Rabellia Juladika , Wijaya Alfan
Published: July 2024

This study aims to synthesize the NiAl-LDH/K4[α-SiW12O40] composite using the coprecipitation method and evaluate its ability to adsorb Cr(VI) from aqueous solutions. The material characterization showed a significant increase in the specific surface area of the composite compared to pure NiAl-LDH, contributing to an enhanced Cr(VI) adsorption capacity. XRD and FT-IR results confirmed the successful synthesis and integration of K4[????-SiW12O40] into the NiAl-LDH structure. At the same time, BET analysis indicated that the specific surface area of the composite doubled compared to pure NiAl-LDH. The adsorption kinetics data indicated that the adsorption process followed the Pseudo-Second-Order (PSO) model with an R2 value close to 1, suggesting the dominance of chemisorption in the Cr(VI) adsorption mechanism. Isotherm analysis showed that the Freundlich model was more suitable than the Langmuir model, indicating that adsorption occurred on a heterogeneous surface with multilayer formation. The Cr(VI) adsorption capacity of the NiAl-LDH/K4[α-SiW12O40] composite reached 17.123 mg/g, higher than that of pure NiAl-LDH at 188.68 mg/g. The Cr(VI) adsorption process involved chemical interactions between Cr(VI) and functional groups on the adsorbent surface, complex formation, and precipitation.
EPISTEMOLOGIA FEMINISTA E ENSINO DE MATEMÁTICA: O PAPEL DA ESCOLA NA REDUÇÃO DAS DESIGUALDADES E DIFERENÇAS
Authors: Maschio Silvia Aparecida , Lopes Thiago Beirigo
Published: July 2024

O crescente número de pesquisas sobre as relações de poder entre homens e mulheres evidencia a necessidade de estudos e mudanças no discurso e nas práticas sociais e educacionais que envolvem gênero (masculino e feminino), relações de gênero e ensino, especialmente de Matemática. O papel da escola é crucial para fortalecer a construção da identidade de gênero sem preconceitos, padrões ou oposições, e para valorizar a mulher na sociedade. Professores podem contribuir para reduzir as desigualdades de gênero dentro e fora da escola, desconstruindo e reelaborando discursos e práticas. Neste artigo, com abordagem qualitativa e pesquisa bibliográfica, reflete-se sobre a prática pedagógica desenvolvida por professores de Matemática no Ensino Fundamental, analisando como ela pode contribuir para a emancipação e o aprendizado em matemática, além de empoderar e fortalecer a mulher na perspectiva de um sujeito ativo na construção de uma sociedade mais igualitária. Conclui-se que a desconstrução do paradigma de gênero na escola passa pela implementação de um currículo que respeite as diferenças, fundamentado legalmente e teoricamente, e por professores com visão crítica que questionem a naturalização do exercício matemático.
Analysis of the Mechanism of Action of Naringnin on Nerve-Damaged Cells Based on Nrf2/HO-1 and NF-κβ Signaling Pathways
Authors: Cui Jian , Ye Ni , Wen Daping , Lei Chao , Hang Jun , Wang Gang
Published: July 2024

Objective: To explore the mechanism of action of naringin in protecting nerve-damaged cells through Nrf2/HO-1 and NF-κβ signaling pathways. Methods: In this study, primary microglia were obtained from 8 neonatal suckling mice and treated with different concentrations of naringin, including a control group (control group) and 4 experimental groups. The activity of primary microglia was assessed using the MTT assay, while apoptosis was evaluated using the TUNEL assay. Molecular biology techniques and cell biology methods were employed to study two types of neuronal cells: highly differentiated PC12 cells and primary microglia. Oxidative stress indicators such as reactive oxygen species (ROS), malondialdehyde (MDA), mitochondrial membrane potential (MMP), and glutathione peroxidase (GSH), as well as inflammatory factors including interleukin-6 (IL-6), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α), were detected. Additionally, the expression of related proteins and genes in the Nrf2 signaling pathway and the NF-κB signaling pathway was examined to elucidate the protective effect of naringnin on neuronal cells during oxidative stress and inflammation, as well as the underlying mechanism. Results: In comparison to the control group, naringin treatment resulted in a statistically significant upregulation of the gene expression of Nrf2 and HO-1 in PC12 cells (P < 0.05). Furthermore, compared to the blank control/negative control/model group, naringin notably mitigated the levels of superoxide dismutase, glutathione, malondialdehyde, and nitric oxide in the rats, along with a significant reduction in apoptosis of neurological injury cells (P < 0.05). Conclusion: Naringin boosts cellular antioxidant capacity by activating the Nrf2/HO-1 signaling pathway, thus mitigating damage to nerve cells inflicted by oxidative stress. Additionally, it reduces the release of inflammatory factors by inhibiting the NF-κB signaling pathway, thereby decreasing inflammation levels. This dual action helps safeguard neural tissues from oxidative and inflammatory damage, ensuring the maintenance of normal nerve cell function.
An Analysis of Strategies for Improving the Information Literacy of College Teachers under the Background of Educational Informatization
Authors: Hu Minjie
Published: July 2024

With the advancement of information technology in higher education in China, the cultivation of information literacy among English teachers in universities has become particularly important. Based on this, the author will elaborate on the importance of cultivating the information literacy of college teachers in this article. Through questionnaires and other forms, a detailed analysis will be conducted on the current situation of information literacy of college English teachers. Strategies for improving the information literacy of college English teachers under the background of educational informatization will be proposed to ensure that the development of college English teaching can meet the needs of the times and comprehensively improve the effectiveness of college English teaching.
Exploration and Practice of Talent Cultivation Model for Virtual Reality Technology Application Based on the Integration of Learning and Training
Authors: Zhang Linghan
Published: July 2024

With the rapid development and widespread application of virtual reality technology, vocational colleges are facing new challenges and opportunities in cultivating virtual reality talents with professional skills and innovative abilities that can adapt well to market demands. This article aims to explore and practice a virtual reality technology application talent training model based on integrating learning and training with the educational characteristics of the Guangdong University of Posts and Telecommunications. This model integrates the teaching resources of the college, practical opportunities for enterprise and industry training needs to build a practical-oriented curriculum system [1], integrating theoretical learning, skill training, and innovative practice to form an integrated educational environment. The study first analyzes the current situation of talent demand in the virtual reality industry and the current situation of higher vocational education. Then, it elaborates on the necessity and feasibility of integrating learning and training. Next, it provides a detailed introduction to the construction process and implementation strategies of the talent training model of integrating learning and training. Finally, the practical effects are evaluated and summarized, and a conclusion is drawn and prospects for the future are presented. The practical results show that the integration of learning and training effectively shortens the distance between teaching and market demand, significantly enhances students’ professional skills and employment competitiveness, and provides new ideas and paths for the cultivation of virtual reality professionals in vocational colleges [2]. The research results of this article have certain theoretical and practical significance for promoting the reform and development of virtual reality technology education and cultivating high-quality technical and skilled talents that meet the needs of the industry.
Construction and Practical Research on the Evaluation System of Vocational Innovation and Entrepreneurship Competition
Authors: Xu Qun
Published: July 2024

In the education and teaching of vocational colleges, innovation and entrepreneurship competitions are of utmost importance. They can reflect students’ innovation and entrepreneurship abilities and the evaluation results can also help to continuously improve and perfect innovation and entrepreneurship education in vocational colleges. Therefore, it is necessary to vigorously build a comprehensive evaluation system for innovation and entrepreneurship competitions in order to improve the level and effectiveness of vocational talent cultivation. Therefore, in the paper, an in-depth exploration was conducted on the construction and practice of the evaluation system for innovation and entrepreneurship competitions in vocational colleges and corresponding improvement suggestions were proposed to strengthen the effectiveness of the evaluation system construction for innovation and entrepreneurship competitions in vocational colleges.
Fabrikasi Komposit PANi/MgO Sebagai Bahan Dasar Sensor Gas Liquefied Petroleum Gas (LPG)
Authors: Wibowo Silvi Rahmawati , Putri Nugrahani Primari
Published: July 2024

PANi sebagai polimer konduktif memiliki performa yang belum optimal sebagai bahan aktif sensor LPG, sehingga perlu di doping dengan bahan material oksida logam seperti MgO. Penambahan MgO akan menghasilkan material baru yang mampu mendeteksi keberadaan gas dengan konsentrasi yang lebih rendah. Penelitian ini bertujuan untuk mengetahui efektivitas komposit PANi/MgO sebagai bahan dasar sensor gas Liquefied Petroleum Gas (LPG). Pembuatan komposit PANi/MgO dilakukan menggunakan metode polimerisasi in-situ dengan variasi komposit PANi/MgO (30%, 40%, dan 50%). Setelah itu sampel komposit hasil fabrikasi diuji menggunakan karaterisasi FTIR, XRD, dan SEM-EDX. Hasil FTIR menunjukkan unsur MgO muncul pada sampel komposit PANi/MgO di bilangan gelombang 3697cm-1 dengan ikatan H-O-H stretching, 544cm-1 dengan ikatan frequency vibrations Mg-O, dan 473cm-1 dengan ikatan Mg-O stretching vibrations. Hasil XRD menunjukkan PANi memiliki sifat amorf dengan struktur kristal parsial dan MgO menujukkan struktur face centered cubic (FCC) yang menghasilkan komposit memiliki puncak difraksi yang tajam pada sudut 42.36° dan 62.79°. Hasil SEM-EDX menunjukkan bahwa komposit berbentuk spherical dengan ukuran pori-pori 326nm yang menunjukkan morfologi permukaan bahan memiliki porositas yang baik senilai 60% untuk respons penginderaan gas.Kata Kunci: Gas, Komposit PANi/MgO, Polimer
Potensi Mimi Mintuna (Horseshoe Crab) Khas Madura Sebagai Daya Tarik Eko-wisata Berbasis Edukasi Masyarakat Jawa Timur
Authors: Rofiah Mauludiyah Nurhidayati , Novelia Adelin , Kautsaranny Safira , Rahayu Dwi Anggorowati
Published: July 2024

Mimi mintuna (horseshoe crab) termasuk hewan Arthropoda yang langka dan terancam punah, namun keberadaanya belum mendapatkan perhatian masyarakat sekitar. Penelitian ini bertujuan untuk mengidentifikasi jenis, menganalisis kekerabatan, nilai similaritas berdasarkan karakteristik morfologi spesies mimi mintuna khas yang ditemukan di Madura sebagai solusi pelestarian jenis serta perannya sebagai daya tarik eko-wisata berbasis edukasi bagi masyarakat Jawa Timur. Metode yang digunakan adalah teknik observasi dan hand sampling dari Pantai Batah Timur, Kwanyar, Bangkalan, Madura, serta spesies acuan  dianut dari buku identifikasi Sekiguchi dan Shuster (2009). Hasil penelitian menunjukkan jenis mimi mintuna khas yang ditemukan Madura adalah Carcinoscorpius rotundicauda, Analisis kekerabatan menunjukkan 3 kelompok kekerabatan yang terdekat hingga terjauh, dan 2 kelompok apomorfi, serta 4 kelompok automorfi. Sampel dari Carcinoscorpius rotundicauda memiliki nilai similaritas 100%. Kemelimpahan jenis Carsinoscorpius rotundicauda di Pantai Batah Timur berpotensi sebagai daya tarik eko-wisata berbasis edukasi bagi masyarakat Jawa Timur.
Ortogonalitas dan Sudut-P dan -I pada Ruang Bernorma-G
Authors: Khaidar Bachtiar Rifai , Jakfar Muhammad
Published: July 2024

Konsep sudut sudah diketahui dan terdefinisi dengan baik di ruang vektor yang dilengkapi dengan hasil kali dalam, tapi sudut yang diciptakan di ruang vektor yang hanya dilengkapi sebuah norm (sudut-P dan -I) tidak baik. Dalam artikel ini, kita akan mengembangkan beberapa konsep sudut antara dua vektor di ruang bernorma-G (generalisasi dari ruang bernorma) dan akan dibahas pula tentang sifat-sifatnya.
Identifikasi dan Tingkat Serangan Ektoparasit pada Budidaya Udang Vannamei (Litopenaeus vannamei) Secara Intensif di Tambak Unit III UPT BAPL Bangil Pasuruan
Authors: Nur Bilqis Atika , Munir Miftakhul
Published: July 2024

Permintaan udang pada saat ini sangat besar, baik pasar lokal maupun internasional sehingga petambak udang meningkatkan produksi dan mutu udang. Faktor yang dapat mempengaruhi mutu udang ialah kualitas air. Di mana kualitas air yang buruk dapat mendatangkan parasit. Tujuan penelitian ini ialah mengidentifikasi jenis ektoparasit dan menganalisis tingkat serangan ektoparasit yang menyerang udang vannamei di kolam P7 tambak unit III Unit Pelaksanaan Teknis Budidaya Air Payau dan Laut Bangil, Pasuruan. Metode untuk identifikasi ialah metode natif. Selanjutnya dianalisis tingkat serangan ektoparasit. Hasil penelitian menunjukkan bahawa jenis protozoa yang ditemukan ialah Vorticella sp. dengan intensitas sebesar 1 individu/ekor kategori ringan dan prevalensi sebesar 13,63% kategori sering, kemudian Zoothamnium sp. dengan intensitas sebesar 5 individu/ekor kategori ringan dan prevalensi sebesar 54,54% kategori sedang.
Potensi Senyawa Chromodoris sebagai Pengikat Reseptor SARS-CoV-2 secara In Silico
Authors: Nur Muchammad Shobachan , Yudiandani Risti Efrilia , Solikah Ayu Ni’matus
Published: July 2024

Meluasnya wabah penyakit Covid-19 saat ini disebabkan sindrom pernapasan akut SARS-CoV-2. Permasalahan yang timbul penyakit infeksi Covid-19 adalah belum ditemukan obat antivirus yang ampuh. Upaya potensial untuk mengatasinya dengan mencari senyawa bioaktif dari invertebrata laut, diantaranya Nudibrachia pada Genus Chromodoris yang kaya senyawa bioaktif, misalnya Chromodorolide A. Penelitian ini bertujuan untuk menganalisis bioaktivitas senyawa Chromodorolide A dari Genus Chromodoris terhadap reseptor 6VXX sebagai reseptor Covid-19. Penelitian ini menggunakan pendekatan uji in silico, yaitu dengan molecular docking senyawa Chromodorolide A, senyawa aktif lainnya yang terkandung dalam Chromodoris spp. serta antivirus Favipiravir terhadap reseptor protein target 6VXX sebagai target penyakit SARS-CoV-2. Analisis hasil molecular docking menggunakan perangkat lunak yaitu PyRx 0.8 dan PyMol. Hasil molecular docking menunjukkan efektivitas senyawa Chromodorolide A secara in terhadap reseptor 6VXX memeroleh skor paling optimal dengan skor binding affinity -6,7 kcal/mol dan skor RMSD 2,243 Å jika dibandingkan dengan Inorolide A, Latrunculin A dan Favipiravir serta menunjukkan adanya bioaktivitas interaksi ikatan hidrogen dengan panjang ikatan 1,9 Å dan 2,4 Å yang lebih stabil jika dibandingkan dengan senyawa Favipiravir. Oleh karena itu, Chromodorolide A berpotensi sebagai sumber bioaktif untuk mengatasi penyakit infeksi virus yang disebabkan oleh SARS-CoV-2.
Keanekaragaman Bivalvia di Pantai Goa Petapa Bangkalan, Madura
Authors: Ramadhan Achmad Bagas Putra , Kurniawan Eka Resi , Dewistamara Marshellia Ghinanda
Published: July 2024

Pantai Goa Petapa terletak di pesisir Pulau Madura tepatnya di Desa Sukolilo, Kecamatan Labang, Bangkalan. Pantai ini merupakan salah satu pantai wisata yang masih dikunjungi oleh wisatawan dan memiliki tipe substrat yang kompleks, yaitu berpasir, berlumpur dan sedikit bebatuan. Penelitian ini bertujuan untuk menganalisis keanekaragaman bivalvia di Pantai Goa Petapa Bangkalan, Madura. Sampel diambil dengan menggunakan metode transek kuadran dengan plot berukuran 1 m x 1 m dan koleksi bebas. Zona intertidal terbagi atas zona intertidal atas, tengah, dan bawah. Sampel diidentifikasi berdasarkan ciri morfologi dan habitat untuk dapat mengetahui jenis bivalvia tersebut. Hasil penelitian menunjukkan terdapat sembilan spesies bivalvia yang berbeda-beda masuk kedalam lima famili. Spesies bivalvia yang ditemukan meliputi Marcia hiantina, Dosinia dilecta, Gafrarium divaricatum, Placamen chloroticum, Gafrarium tumidum, Hiatella arctica, Volachlamys singaporina, Barbatia amygdalumtostum, dan Perna viridis. Keanekaragaman bivalvia di Pantai Goa Petapa, Bangkalan Madura tergolong kedalam kategori rendah.
Identifikasi Mutasi RS7903146 pada Gen TCF7L2 pada Penderita Diabetes Tipa II di Wilayah Sidoarjo
Authors: Huesein Wa Ode Asma’ul Husna , Mushlih Miftahul , Rini Chylen Setiyo , Hanum Galuh Ratmana
Published: July 2024

Diabetes Mellitus Tipe 2 adalah gangguan sistem endokrin yang dipengaruhi oleh faktor genetik dan pilihan gaya hidup. Mutasi pada gen TCF7L2, khususnya pada rs7903146, telah erat terkait dengan T2DM karena efek gangguan pada sekresi insulin. Tujuan utama dari penelitian ini adalah mengidentifikasi mutasi pada gen TCF7L2 dalam populasi T2DM di Wilayah Sidoarjo. Sebanyak tujuh sampel digunakan dalam penelitian ini dengan mengaplikasikan teknik isolasi DNA, PCR, dan sekuensing. Sampel DNA secara khusus diperbanyak untuk menargetkan gen TCF7L2 selama 318 pasangan basa. Hasil penelitian ini menunjukkan ketiadaan mutasi pada rs7903146.
 
Type 2 Diabetes Mellitus is an endocrine system disorder influenced by genetic factors and lifestyle choices. Mutations in the TCF7L2 gene, particularly at rs7903146, have been closely associated with T2DM due to their disruptive effects on insulin secretion. The primary objective of this study is to identify mutations in the TCF7L2 gene within the T2DM population of the Sidoarjo Region. A total of seven samples were utilized in this research, employing DNA isolation, PCR, and sequencing techniques. The DNA samples were specifically amplified to target the TCF7L2 gene over a stretch of 318 base pairs. The findings of this study indicate an absence of mutations at rs7903146.
Keanekaragaman Gastropoda di Pantai Tambakrejo, Kabupaten Blitar
Authors: Wardani Sonya Ainur Rokhimah
Published: July 2024

Salah satu pantai selatan di Pulau Jawa yang terletak di Jawa Timur, tepatnya di Kabupaten Blitar adalah Pantai Tambakrejo, dimana di pantai tersebut terdapat keanekaragaman gastropoda dengan karakteristik yang berbeda-beda. Tujuan penelitian ini antara lain: (1) menganalisis keanekaragaman gastropoda di zona intertidal Pantai Tambakrejo, Kabupaten Blitar, (3) Menganalisis kelimpahan relatif gastropoda di Pantai Tambakrejo, Kabupaten Blitar. Penelitian ini menggunakan metode kuantitatif dengan sampling bebas, selanjutnya data dianalisis menggunakan pengukuran indeks keanekaragaman dan kelimpahan relatif. Hasil penelitian menunjukkan terdapat 6 species gastropoda, yaitu Clithon oualaniense, Oppomorus funiculatus, Littoraria scabra, Strigatella paupercula, Nerita polita, dan  Monitaria moneta dengan indeks keanekaragaman adalah 1,165. Berdasarkan perhitungan dan analisis data tersebut, maka keanekaragaman gastropoda di Pantai Tambakrejo, Kabupaten Blitar termasuk ke dalam kategori rendah dengan kestabilan komunitas sedikit.
Karakteristik Antibakteri dari Wound Dressing PVA – Sodium Alginat
Authors: Putri Ramadhani Novtantian Erlinda , Kusumawati Diah Hari
Published: July 2024

Sodium Alginat merupakan polimer bahan alam yang berkembang dalam bidang kesehatan dengan sifat biokompatibel, biodegradasi, dan sifat antibakteri yang baik. Tujuan penelitian ini adalah menganalisis karakteristik wound dressing dari PVA-Sodium Alginat dan menganalisis efektivitas antibakteri dari wound dressing PVA-Sodium Alginat. Sintesis nanofiber dilakukan menggunakan metode electrospinning dengan parameter yang digunakan yaitu laju alir 1 ml/jam, jarak jarum antar kolektor sejauh 13 cm, serta tegangan sebesar 15 kV. Nanofiber yang dihasilkan kemudian dikarakterisasi menggunakan FTIR, SEM, uji antibakteri, dan uji tarik. Hasil FTIR nanofiber PVA-Sodium Alginat diperoleh gugus fungsi C-H yang menunjukkan adanya PVA , serta COO asimetris dan simetris dari kandungan Sodium Alginat. Karakterisasi SEM menunjukkan morfologi berbentuk serat dengan ukuran diameter pada rentang 99 – 142 nm, porositas 43% - 47%, dan ukuran pori 0,915 m – 1,121 m . Hasil karakterisasi SEM meliputi struktur morfologi, ukuran diameter, porositas dan ukuran pori nanofiber PVA-Sodium Alginat yang memenuhi karakteristik sebagai wound dressing yaitu pada variasi Sodium Alginat 3%. Hasil uji tarik nanofiber PVA-Sodium Alginat didapatkan nilai kuat tarik 3,26 MPa, regangan sebesar 6%, dan modulus elastisitas sebesar 0,54 MPa. Nanofiber PVA-Sodium Alginat memiliki aktivitas antibakteri yang sangat baik pada bakteri gram negatif (Eschericia coli) dengan efektivitas antibakteri sebesar 97,5%, namun tidak dapat menghambat pertumbuhan untuk bakteri gram positif (Staphylococcus aureus).
Kajian Tanaman Pekarangan di Pulau Kangean, Sumenep, Madura, Jawa Timur
Authors: Indah Novita K. , Kusumawati Nita , Mugiyanto Agus
Published: July 2024

Pekarangan keluarga masyarakat Pulau Kangean mempunyai hubungan yang erat dengan penghuni rumah  dalam kehidupan sehari-hari. Pengelolaan dan pemanfaatan pekaran dapat menjadikan pekarangan  sebagai lumbung hidup, warung hidup, dan apotek hidup sertsa menjadi lahan konservasi kekayaan plasma nutfah. Tujuan penelitian ini adalah untuk menginventarisasi spesies, menganalisis spesies tanaman pekarangan berdasarkan kegunaannya dan   menganalisis bagian tanaman yang digunakan dengan cara mendeskripsikan bagiam dan kegunaan bagian tersebut secara kualitatif. Penelitian ini menggunakan metode eksplorasi  dengan bertempat di Kecamatan Arjasa dan wawancara terhadap masyarakat  dengan snowball sampling. Berdasarkan familinya, tanaman yang paling banyak ditemui berasal dari famili Anacardiaceae dan Zingiberaceae. Anggota Anacardiaceae dikonsumsi bagian buah sedangkan anggota Zingiberaceae digunakan untuk bumbu masak dan rempah obat atau tanaman toga. Spesies yang ditemukan sebanyak 37 jenis. Kegunaannya antara lain sebagai sumber pangan, tanaman hias, peneduh jalan, tanaman obat dan rempah. Bagian tumbuhan yang digunakan meliputi daun, batang, buah, buah, dan biji atau dengan kata lain seluruh bagian tanaman dapat digunakan oleh masyarakat.
Keanekaragaman Kupu-Kupu (Lepidoptera) di Ruang Terbuka Hijau Taman Abhirama, Kabupaten Sidoarjo
Authors: Nelyzza Nelyzza , Ningsih Ika Kusuma
Published: July 2024

Kupu-kupu merupakan salah satu keanekaragaman hayati yang harus dijaga kelestariannya. Kupu-kupu dapat dijumpai di sekitar kita, misalnya di taman kota atau ruang terbuka hijau kota. Taman Abhirama merupakan salah satu ruang terbuka hijau yang ada di Sidoarjo, Jawa Timur. Tujuan penelitian ini adalah untuk menganalisis keanekaragaman kupu-kupu (Lepidoptera) Filum Arthropoda pada habitat ekowisata di kawasan Ruang Terbuka Hijau yakni Taman Abhirama, Kabupaten Sidoarjo. Sampling dilakukan dengan menggunakan swept nest di tiga stasiun. Identifikasi berdasarkan ciri morfologi. Data dianalisis dengan menghitung indeks keanekaragaman. Berdasarkan hasil identifikasi, telah ditemukan sepuluh spesies kupu-kupu dengan tiga famili, yakni Nymphalidae, Pieridae, dan Lycaenidae serta total individu sebanyak 21 ekor. Nilai indeks keanekaragaman keseluruhan sebesar 2,202. Dengan demikian, indeks keanekaragaman tersebut berada pada rentang nilai 1,0 ≤ H ≤ 3,322 yang menunjukkan tingkat keanekaragaman sedang.