bluuebunny/crossref_metadata_2025 huggingface dataset:
Practicing creative thinking skills: Inquiry base activity sheets development in protists learning material
Authors: Putri Rossanita Truelovin Hadi , Raharjo Raharjo , Racmadiarti Fida
Published: May 2021

Protist learning materials have been developed by many researchers, but no one has developed learning tools by training students' creative thinking skills. This study aims to produce LKPD based inquiry on protist material and to train creative thinking skills, by describing the validity and effectiveness of LKPD on protist material. The LKPD developed refers to the 4D model which consists of the stages of define, design, develop, and disseminate. The research design used was the One-Group Pretest-Posttest Design. LKPD was tried out on 12 students of class XI MIPA SMA. After using LKPD, the validity and effectiveness data were analyzed descriptively quantitatively. The validity of the LKPD is measured based on the assessment of the education expert lecturers and materials. The effectiveness of protist LKPD is measured based on the learning outcomes of students and students' responses. The results showed the validity of the LKPD was 99.4% with the very valid category. The effectiveness based on the learning outcomes of students was 92% with the category very effective and the response of students was 99%. Based on the results of this assessment, it can be concluded that LKPD based on the inquiry on protist material to train creative thinking skills is declared valid and effective.Keywords: Activity sheets, inquiry learning, creative thinking, protists
Periodontal microorganisms and diagnosis of malignancy: A cross-sectional study
Authors: Söder Birgitta , Källmén Håkan , Yucel-Lindberg Tülay , Meurman Jukka H.
Published: May 2021

BACKGROUND:

Oral infections associate statistically with cancer.

OBJECTIVE:

We hypothesized that certain periodontal microorganisms might specifically link to malignancies in general and set out to investigate this in our ongoing cohort study.

METHODS:

A sample of 99 clinically examined patients from our cohort of 1676 subjects was used to statistically investigate the associations between harboring periodontal microorganisms Aggregatibacter actinomycetemcomitans ( A.a), Porphyromonas gingivalis ( P.g), Prevotella intermedia ( P.i), Tannerella forsythia ( T.f) and Treponema denticola ( T.d). We used oral infection indexes and the incidence figures of malignancies as registered in 2008–2016 in the Swedish National Cancer Register.

RESULTS:

The pathogen A.a showed strong association with malignancy in 32 out of the 99 patients while P.g and P.i were more prevalent among patients without malignancy. In principal component analyses, A.a appeared in the strongest component while the second strongest component consisted of a combination of T.f and T.d. The third component consisted of a combination of P.g and P.i, respectively. Of basic and oral health variables, gingival index appeared to be the strongest expression of inflammation (Eigen value 4.11 and Explained Variance 68.44 percent).

CONCLUSIONS:

The results partly confirmed our hypothesis by showing that harboring certain periodontal bacteria might link to malignancy. However, the associations are statistical and no conclusions can be drawn about causality.
O paradoxo da mudança
Authors:   Médico de Família, Jacinto Nuno
Published: May 2021

O paradoxo da mudança
Luxación traumática recurrente de cadera asociada a fractura de cabeza femoral reconstruida con autoinjerto de cresta ilíaca
Authors: Rubio-Saez Israel , Merino-Rueda Luis Rodrigo , Pallares-Sanmartin Javier , De Godos-Martínez Diego , Ibarzabal-Gil Aitor , Rubio-Suárez Juan Carlos
Published: May 2021

Las fracturas de la cabeza femoral de la cadera son extremadamente infrecuentes, pero probablemente se relacionen con luxaciones traumáticas de la cadera. Ambas lesiones requieren un tratamiento urgente para evitar más complicaciones.
Paciente varón de 19 años que fue recibido tras un accidente automovilístico de alta energía con traumatismo craneoencefálico y toracoabdominal severo y fractura de cabeza femoral desplazada con luxación posterior de cadera sin fractura acetabular. Se realizó una reducción abierta emergente y fijación interna con 2 tornillos sin cabeza, así como reparación de la cápsula posterior. Tras 1 mes de internación en Unidad de Cuidados Intensivos, sufrió un nuevo episodio de luxación posterior de cadera. En consecuencia, se obtuvo una segunda reducción quirúrgica exitosa y la estabilidad de la cadera se logró mediante la reconstrucción posterior con autoinjerto de cresta ilíaca fijado con tornillo canulado y reparación de la estructura posterior. Dos años después, pudo caminar de forma independiente y no presenta ningún signo de enfermedad degenerativa articular ni necrosis avascular.
Peran Komitmen Organisasional Dalam Pengaruh Kepuasan Kerja Dan Kualitas Kehidupan Kerja Terhadap Kinerja Karyawan PT. Ramayana Lestari Sentosa, Tbk Cabang Sleman
Authors: Kurniawan Ignatius Soni , Nurlita Koni Awes
Published: May 2021

Penelitian bertujuan untuk mengetahui pengaruh kepuasan kerja dan kualitas kehidupan kerja terhadap kinerja karyawan dengan komitmen organisasional sebagai variabel pemediasi. Penelitian dilakukan terhadap 80 karyawan PT. Ramayana Lestari Sentosa, Tbk Cabang Sleman. Pengumpulan data dilakukan melalui survei dengan kuesioner yang didistribusikan secara offline. Teknik pengambilan sampling dengan sampel jenuh.  Jenis penelitian ini bersifat deskriptif kuantitatif. Metode analisis data dengan uji instrumen, uji asumsi klasik, uji hipotesis, dan sobel test. Temuan menunjukkan bahwa kepuasan kerja tidak berpengaruh secara langsung terhadap kinerja karyawan yang dimediasi oleh komitmen organisasional. Ditemukan juga kualitas kehidupan kerja berpengaruh langsung terhadap kinerja dengan dimediasi oleh komitmen organisasional.
Pengaruh Pelatihan Dan Motivasi Terhadap Kinerja Karyawan Pada Bank BJB di Cabang Balaraja Banten
Authors: Hermawati Rahmi , Firdaus Abdurrahman , Suryani N Lilis , Rozi Achmad , Erlangga Heri
Published: May 2021

Tujuan penelitian ini adalah untuk mengetahui pengaruh pelatihan dan motivasi terhadap kinerja karyawan pada Bank BJB Di Cabang Balaraja Banten baik secara parsial maupun secara simultan. Metode yang digunakan adalah metode yang digunakan dalam penelitian ini adalah asosiatif kausal dengan pendekatan kuantitatif. Teknik sampling yang digunakan adalah sampel jenuh menggunakan dengan 98 responden. Analisis data menggunakan uji validitas, uji reliabilitas, uji asumsi klasik, analisis regresi, analisis koefisien korelasi, analisis koefisien determinasi dan uji hipotesis. Hasil penelitian ini adalah bahwa pelatihan berpengaruh signifikan terhadap kinerja karyawan dengan persamaan regresi Y = 17,500 + 0.563X1, koefisien korelasi 0,659 artinya kedua variabel memiliki hubungan yang kuat dengan koefisien determinasi 43,4% dan Uji hipotesis diperoleh t hitung> t tabel atau (8,587>1.985) Motivasi berpengaruh signifikan terhadap kinerja karyawan dengan persamaan regresi Y = 15,802 + 0,607X2. Koefisien korelasinya sebesar 0,607 artinya keduanya memiliki hubungan yang kuat dengan koefisien determinasi sebesar 36,8% dan uji hipotesis yang diperoleh t hitung> t tabel atau (7,482>1,985). Pelatihan dan motivasi secara simultan berpengaruh signifikan terhadap kinerja karyawan dengan persamaan regresi Y = 11,164 + 0,394X1 + 0,366X2. Nilai koefisien korelasinya yang diperoleh sebesar 0,713 artinya variabel independen dengan variabel dependen memiliki hubungan yang kuat dengan koefisien determinasi sebesar 50,8% sedangkan sisanya 49,2% dipengaruhi oleh faktor lain. Pengujian hipotesis diperoleh nilai F>F tabel atau (49,032>2,700) dengan demikian H0 ditolak dan H3 diterima. Artinya terdapat pengaruh simultan yang signifikan antara pelatihan dan motivasi terhadap kinerja karyawan pada Bank BJB Cabang Balaraja Banten.
IMPROVING STUDENTS VOCABULARY THROUGH BBC’S VIDEO IN INSTAGRAM AT JUNIOR HIGH SCHOOL
Authors: Sipayung Kammer
Published: May 2021

Vocabulary is a linguistics ellement of language skills. The purpose of this research is to describe the role of BBC’s Video in Instagram for improving students’ mastery on vocabulary. This research is a class room action research based on the theory of Kemmis and McTaggart (1988). The researcher used three times of classroom action cycle to achieve the goal. The population of this research is students at SMP Negeri 3 Medan and the sample is students at grade seven-two. The data of this classroom action research is score from each cycle. The result of this research shows us that BBC’s Video in instagram as a media of teaching English is able to improve students’ mastery on vocabulary. It can be seen in the first cycle their average score is 60.1, in the second cycle is 72.3 and the last cycle is 85.1. This result shows us that video in instagram is a good instrument to improve the students’ mastery in vocabulary. It is suggested to other English teacher to make this media as an alternative media as far as the teaching method is supported to use.
Das Geschäft der Wirtschaftsschule
Authors: Torquato Paola Regazoni , Araujo Fernando Oliveira de
Published: May 2021

Dieser Artikel zielt darauf ab, die von den wichtigsten Wirtschaftsschule versprochenen Lieferungen mit den von den Schülern erwarteten zu vergleichen, um die administrativen Prozesse zu verbessern, die von den Institutionen verwendet werden. Dies ist eine systematische Überprüfung der Literatur, begleitet von explorativen empirischen Forschungen, die den Stand der Technik und das Innovationspotenzial in Bezug auf die Managementprozesse von Wirtschaftsschule in Bezug auf die Markterwartungen beschreiben. Es wurden fünf Attribute identifiziert, die für den Erfolg von Wirtschaftsschule relevant sind: Bereitstellung von Management-Lernangeboten; organisatorische Flexibilität; strategische Leistungskennzahl; Auswirkungen und Ergebnis. Dies ist eine beispiellose Studie auf nationaler Ebene, die darauf abzielt, die Managementprozesse der Wirtschaftsschule von Rio de Janeiro zu verbessern. Die Ergebnisse beschränken sich auf den untersuchten Fall.
Mudança no padrão demográfico dos doadores de órgãos no Estado do Paraná de 2011 a 2019
Authors: Badoch Arlene Terezinha Cagol , Silveira Fabio , Von Stein Altair , Giugni Juliana Ribeiro
Published: May 2021

A demanda de órgãos para transplante necessita de um sistema eficaz na identificação de potenciais doadores. A expansão da base de doadores no Paraná, atingindo 43,8 doadores/pmp em 2019, ocorreu pelo aumento da média de idade (46,3±1,68), principalmente da faixa etária dos 50 aos 79 anos. Houve mudança na principal etiologia de morte encefálica, modificada dos traumatismos crânio-encefálicos (28,10%), para os acidentes vasculares cerebrais (46,35%). A média do número de transplantes realizados por cada doador efetivo foi de 2,14±0,37, com média de 52,24±18,48 transplantes pmp. A queda da razão transplantes/doador efetivo é contrastada com o comportamento da linha dos transplantes/pmp. Perfil de doadores ideais foi modificado para doadores de critérios expandidos. A ampliação da base de doadores consegue beneficiar um número cada vez maior de pacientes.
Estratégias de comunicação em saúde mental em tempos de pandemia
Authors: Lima Carolina Palmeiro , Fernandes Quesia Cataldo , Manara Kalil Maihub , Duarte Michael de Quadros , Santo Manuela Almeida da Silva , Giordani Jaqueline Portella , Vaz Rodrigo Trapp Gampe , Vasconcelos Valmir Dorn , Portalino Ernesto Alvarado , Trentini Clarissa Marceli
Published: May 2021

Transtornos mentais estão entre as principais causas de adoecimento no mundo. Essas questões se agravam principalmente em momentos de grande instabilidade, como no caso da pandemia de COVID-19, justificando ainda mais o uso de estratégias de divulgação e disseminação de cuidados em Saúde Mental. O objetivo desse artigo é apresentar um método de estruturação de equipe e comunicação em saúde (CS) acessível, prático e com potencial de impacto sobre o comportamento dos indivíduos. Foram produzidos cards com informações sobre cuidados com a saúde mental durante a pandemia para serem divulgados em redes sociais a partir do método SAM (Suitability Assessment of Materials) e da literatura em CS. Concluiu-se que proporcionar à população informações sobre cuidados em saúde pode ter um impacto positivo, alinhando-se com os pressupostos da Atenção Primária em Saúde (APS). Tanto cidadãos quanto o poder público, ao investir em APS, podem economizar recursos a médio e longo prazo.
Doadores de órgãos efetivos no Paraná e correlação com o Índice de Desenvolvimento Humano Municipal
Authors: Badoch Arlene Terezinha Cagol , Silveira Fabio , Porto Silveira Fábio , Von Stein Altair , Giugni Juliana Ribeiro
Published: May 2021

O Paraná se destaca na oferta de órgãos para transplante. O sistema é inserido no Sistema Único de Saúde, portanto influenciado por desigualdades regionais. O índice de desenvolvimento humano municipal (IDHM) é utilizado para análise e compreensão do desenvolvimento e sua relação com a doação de órgãos é desconhecida. Objetivo é analisar a correlação do IDHM com a doação de órgãos no estado no período de 2011 a 2019. Ocorreram 2875 doações efetivas em 7,27% dos municípios, com diferença do IDHM daqueles com (0,7514±0,03) e sem (0,6981±0,03) doação. Municípios com IDHM alto e muito alto (59,65% do total), foram responsáveis por 97,46% das doações. O agrupamento por Regionais de Saúde demonstra correlação linear positiva entre o IDHM e as doações efetivas por milhão de população, porém sem diferença do IDHM médio entre elas. Há correlação entre o IDHM e os doadores efetivos, não sendo o único fator de influência.
Determinantes sociais da saúde relacionados à gravidez na adolescência
Authors: Moura Francyely dos Santos , Silva Júnior José Antonio da , Rolim Ana Carine Arruda , Silva Kleylenda Linhares da , Jacob Lia Maristela da Silva
Published: May 2021

O objetivo foi revisar e descrever na literatura nacional e internacional os determinantes sociais da saúde relacionados à gravidez na adolescência. Trata-se de uma revisão integrativa da literatura, realizada entre os meses de agosto e novembro de 2019. A busca dos artigos foi realizada nas bases de dados eletrônicas PubMed, SciELO e Portal Regional da Biblioteca Virtual em Saúde. A amostra final constituiu-se de 15 artigos, sendo agrupados em categorias temáticas: determinantes sociais da saúde e gravidez na adolescência, associação entre educação e a gravidez na adolescência, conhecimento dos adolescentes e pais relacionado à saúde sexual e reprodutiva. Os determinantes sociais da saúde têm uma relação com a gravidez na adolescência e precisam ser mais explorados nos estudos para maiores intervenções, sendo importantes para formulação de políticas com o objetivo de melhorar as condições de saúde da população.
Review of Design and Build Construction: Descriptive Statistics in one of the South East Asia country
Authors: Raymond Yip Hock Seng , Anuar Herman Shah
Published: May 2021

In the area of the construction sector, the primary concern is economic growth. There are many issues and challenges associated with it. The growth and rapid development of this industry put their players, mainly the construction firms feeling the heat by competing with each other. The main challenge is the completion period for a particular project. This study was done in Manila, Philippines, where Design and Build (D&B) method has gained much interest and considered very important today. The rise of new innovative systems saw the emergence of new factors in the construction industry that will become future adoption. This study focuses on factors affecting the successful completion period of the construction industry, whereby it is very crucial for the country's economic and market development. A quantitative research methodology was applied in this study. A total of 967 survey questionnaires sent out, and only 396 respondents fit to be analysed. Respondents involved were contractors, consultants, and developers. It was learned that critical success factors in project management play significant roles in driving projects to examine the determinants of success completion time of Design & Build construction projects. Findings from this study shall be used by the authority in drafting a policy guideline for future construction development. It is hoped that this study provides a better understanding of construction challenges for future undertaking.
Chemical Warehouse Operations: Experience from SWIFT Integrated Logistics Sdn. Bhd
Authors: Nagalingam Kannadasan , Anuar Herman Shah
Published: May 2021

This article investigated the comprehensive risk management model practised at SWIFT Integrated Logistics chemical storage operations. The objective is to systematically illustrate the risk factors by identifying risks and mitigating them from the flow of the operation. By reducing or containing the risk factors, we are able to provide a conducive, safe, secure working environment with initiatives toward zero-incident reporting cases. A qualitative research method was applied in this study. Respondents selected for this study were at the managerial level at SWIFT Integrated Logistics with experience working in warehouse operations for more than five years. SWIFT Integrated Logistics management wanted to diversify its warehouse customer's portfolio and accepted new business opportunities in chemicals warehouse storage. The move contributed greatly to the business strategy and finance, but they faced serious risk management issues, which resulted in six (6) incidents and raised the level of anxiety and concern among the warehouse team on health & safety issues. Future studies may look into additional strategies to implement a better warehouse risk management model or plan for a chemical warehouse. This study suggested that regular or continuous training should be provided to the staff. Basic first aid kit training is an example of the mandatory training that should be part of the job standard operating procedure. This paper contributes to the limited existing study on chemical warehouse operations. Experience and measures taken by SWIFT management may provide some ideas to improve the management of chemical warehouse for other warehouse operators. Although chemical warehouse operation safety is important, there is scarce academic research that explores this issue.
Marco conceptual para organizaciones saludables en el contexto ecuatoriano
Authors: Córdova-Cano Arturo , Loor-Colamarco Ignacio
Published: May 2021

Las organizaciones saludables impactan directamente el desempeño individual de sus colaboradores, lo que repercute en el funcionamiento y el rendimiento global de la organización. No obstante, la noción de organización saludable no es un modelo de talla única, sino que varía de un contexto a otro. Esta investigación desarrolla el concepto de organización saludable para el contexto empresarial ecuatoriano. El estudio es de tipo exploratorio y recoge descripciones ricas de ejecutivos y expertos en la gestión de talento humano. El estudio también considera reportes técnicos de organismos que han abordado la noción de organización saludable, como la Organización Mundial de la Salud y la Organización Internacional del Trabajo. Los argumentos identificados en estos documentos, además de los datos bibliográficos, fueron contrastados con los datos recogidos por medio de entrevistas a profundidad. El análisis de los datos utilizó teoría fundamentada, lo que permitió identificar los temas clave y sus interrelaciones. El resultado de la investigación fue un marco conceptual para organizaciones saludables en Ecuador. La relación expuesta examinó el bienestar del trabajador, las prácticas que promueven bienestar, la relación entre bienestar y productividad, y los desafíos del bienestar laboral en el Ecuador. Por último, se determinó que existe escasa investigación en Ecuador con relación al concepto de bienestar sus prácticas o que analicen la dependencia con la salud financiera o rentabilidad de una organización. Asimismo, se encontró que es necesario desarrollar patrones o estándares que permitan gestionar ambientes saludables, tomando en cuenta la implementación de planificación del bienestar, la transparencia, la gestión de equipos y la aplicación de prácticas saludables.
Academic Self-Concept and Critical Thinking Dispositions: Devising a Predictive Model of College Students’ Degree Commitment
Authors: Chatzinikolaou Marios Dimitrios , Tsirides Andreas
Published: May 2021

Educational researchers incessantly endeavor to address underlying reasons for academic success/failure, and Degree Commitment constitutes a critical sought-after academic outcome regarding college students, which is considerably associated with higher student retention rates. Educational institutions may create effective preventive strategies and interventions for minimizing attrition issues by identifying factors leading to higher Degree Commitment. The aim of the current research was to explore the potential predictive relationship between higher demonstration of college students’ Academic Self-Concept and higher levels of Critical Thinking Dispositions on their commitment of further pursuing their chosen degree. A questionnaire-based survey method was employed, adopting a correlational design on a recruited purposive sample of 120 Greek college students of a privately-owned educational institution. A multiple regression statistical analysis generated a weak positive correlation (9.2%) between the predictors, with Academic Self-Concept being the strongest predictor of Degree Commitment, implying that the combination of the aforementioned academic facets significantly predicts Degree Commitment, but with a small generalization explanatory power to a population sharing common characteristics with the utilized sample. Although the devised model is of minimal practical use, it proposes an initial attempt to construct a holistic model of academic success, while simultaneously highlighting the necessity for developing interventions that robustly target Critical Thinking Dispositions and, most importantly, Academic Self-Concept. Future research may explore factors influencing the predictors under investigation, compare them between students deriving from traditional educational systems and those deriving from international educational systems, and explore alternative factors concerning college success and attrition within various sociocultural contexts.
Previsão da demanda brasileira de biodiesel utilizando redes neurais artificiais
Authors: Caires Kaique Vitor Louzada , Simonelli George
Published: May 2021

O biodiesel é um combustível renovável utilizado como uma alternativa para substituir de modo total ou parcial o diesel de petróleo. A porcentagem obrigatória desse biocombustível adicionado ao diesel fóssil no Brasil tem sido elevada constantemente. Prever a quantidade de biodiesel que será demandada futuramente é essencial para manter o balanço nacional superavitário e auxiliar nas tomadas de decisões do setor. As redes neurais artificiais (RNAs) são úteis para previsão de diferentes tipos de demandas. Assim sendo, esse estudo utiliza redes neurais artificiais na previsão da demanda brasileira de biodiesel. A RNA proposta neste trabalho englobou dados obtidos de um modelo não-paramétrico de previsão de demanda baseado em séries temporais. O modelo não-paramétrico considerou as tendências e sazonalidade dos dados para previsão da demanda de biodiesel. Foram modeladas 100 redes do tipo perceptron multicamadas com retropropagação do erro para dois cenários do biodiesel brasileiro (uso de 15% (B15) ou 20% (B20) de biodiesel ao diesel). Todos os valores de R2 maiores que 0,99 para as redes simuladas e RMSE<2% comprovam que o modelo de RNA desenvolvido possui alta precisão em prever a demanda de biodiesel. A melhor rede para cada cenário foi determinada por análise heurística do RMSE. Os resultados das melhores RNA’s simuladas mostraram um crescimento da demanda de biodiesel de 2019 a 2050 de 150,63% para o B15, e de 229,73% para o B20. Ambos cenários de aumento de demanda são justificados pela elevação gradual da porcentagem obrigatória do biodiesel ao diesel. Dessa forma, os resultados crescentes da demanda de biodiesel comprovam a busca do país por um combustível não-tóxico, biodegradável e renovável na sua matriz energética.
Percepção de enfermeiros da rede cegonha sobre sinais do início do trabalho de parto
Authors: Costa Ivelise Fhrideraid Alves Furtado da , Sousa Francisco Stélio de , Ferreira Adriana Gomes Nogueira , Oliveira Fernanda Albuquerque de , Souza Ana Raquel Silva , Guedes Tatiane Gomes , França Inácia Sátiro Xavier de , Baptista Rosilene Santos
Published: May 2021

Objetivos: Identificar os sinais de início de trabalho de parto, segundo os profissionais da rede cegonha. Metodologia: Trata-se de um estudo transversal, com abordagem de dados primários, realizado em unidades da Rede Cegonha, no período de agosto de 2017 a julho de 2019. A amostragem foi de 84 enfermeiros. A coleta de dados foi efetuada por formulário contendo variáveis de interesse do estudo. Efetuou-se estatística descritiva, para toda a estatística adotou-se o nível de significância de 5%. Esta pesquisa foi aprovada sob-registro CAAE: 87854418.3.0000.5187.Resultados: Quanto aos sinais de início do trabalho de parto foram citados: saída do tampão mucoso, contrações que aumentam sua força constantemente e dor que inicia na região lombar e migra para o púbis (47,94%, n=35).Também foram citadas: contrações uterinas com padrão diferente das recomendações vigentes e perdas vaginais (52,63%, n=40); contrações, perdas vaginais e dilatação (10,52%, n=8); só contrações (15,76%, n=12). Conclusões: Não há apenas um sinal ou sintoma que seja definitivo para identificação do início de trabalho de parto, mas que deve-se levar em consideração a subjetividade e multifatoriedade que envolve o atendimento, reconhecendo cada sinal e sintoma. Sendo necessário o aperfeiçoamento do preparo para o parto a fim de colaborar para uma melhor assistência.
Idade materna e associação com intercorrências na gestação e parto
Authors: Maia Maria Rita Guimarães , Morceli Glilciane , Silva Suelen Umbelino da , Carvalho Maria Dalva de Barros , Pelloso Sandra Marisa
Published: May 2021

Objetivo: Analisar a idade materna, associação com intercorrências na gestação e a influência na determinação do parto. Método: Estudo observacional, retrospectivo, transversal com puérperas cujos partos ocorreram no ano de 2016, em hospital do interior paulista. Resultados: De 1130 prontuários analisados, 22,2% apresentaram <19 anos e 10,3% ≥ 35 anos. A infecção do trato urinário ocorreu em 21,1% das mulheres, o trabalho de parto prematuro (5,3%), descolamento prematuro de placenta (5,2%) e doença hipertensiva específica da gravidez (4,2%). diabetes e hipertensão arterial foram mais frequentes entre mulheres com ≥ 35 anos, 57,9% das mulheres tiveram parto normal e 42,1% cesárea, taxa superior entre mulheres < 19 anos. A hipertensão associou-se à cesárea em gestantes ≥ 35 anos e a doença hipertensiva específica da gravidez ao parto normal. Conclusão: A idade materna, gestantes com < 19 anos associou-se a cesariana e em gestações > 35 o parto vaginal foi mais frequente e independente da idade a intercorrência gestacional mais frequente foi a infecção do trato urinário.
Pneumonia ocasionada pela COVID-19 e a importância do diagnóstico como benefício para o tratamento
Authors: Silva Filho Paulo Sérgio da Paz , Figueiredo Bruno Leonardo de Sousa , Kirchesch Cryshna Letícia , Amaral Salomão Mendes , Santos Lucas Daniel Lima dos , Ferreira João Pedro Nascimento , Farias Maria Divina dos Santos Borges , Batista Woodyson Welson Barros da Silva , Calaça Mickaelle Bezerra , Mesquita Gerardo Vasconcelos , Campelo Vitor Eulálio Sousa , Nascimento Hélio Mateus Silva , Carvalho Neto Amadeu Luis de , Sousa Junior Gilberto dos Santos , Silva Élio Rodrigues da , Cardoso Arquimedes Cavalcante , Serzedo Maria Clara Cronemberger Guimarães , Oliveira Carla Patrícia de Carvalho
Published: May 2021

O presente estudo teve como objetivo descrever casos de pneumonia ocasionada pela COVID-19 e a importância do diagnóstico como benefício para o tratamento. Trata-se de um estudo descritivo, do tipo revisão integrativa, de caráter qualitativo. O estudo foi realizado nos meses de janeiro a março de 2021 e constituída a partir da identificação do problema e objetivos, elaboração da pergunta norteadora, busca na literatura, avaliação dos dados, análise e síntese de dados e discussão e apresentação dos resultados. As questões da pesquisa foram: “Qual a relação da pneumonia com a COVID-19?", "Qual a importância do diagnóstico rápido da COVID-19?" e "Qual o tratamento empregado em pacientes com pneumonia ocasionada pela COVID-19?".  Os critérios de inclusão foram: artigos disponibilizados na íntegra, disponíveis nos idiomas português, espanhol e inglês e publicados entre os anos de 2019 e 2021. Os critérios de exclusão foram: artigos incompletos, cartas ao editor, debates, resenhas, resumos ou artigos publicados em anais de eventos, indisponíveis na íntegra e duplicados. Foram considerados, inicialmente, 346 estudos com a temática proposta; dentre estes, foram excluídos 120 estudos, de acordo com os critérios de exclusão estabelecidos. Após a aplicação dos critérios de inclusão, restaram 12 estudos. O diagnóstico da pneumonia por COVID-19 é possível através de PCR-TR positivo ou presença de alta suspeição clínica (clínica compatível + epidemiologia favorável) associada à tomografia computadorizada com padrão em vidro fosco periférico bilateral de lobos inferiores.
Chitosan and hydroxyapatite scaffolds with amoxicillin for bone repair
Authors: Ponciano Rosemary Cunha de Oliveira , Costa Ana Cristina Figueiredo de Melo , Barbosa Rossembérg Cardoso , Fook Marcus Vinícius Lia , Ponciano João José
Published: May 2021

The bone repair process, among other physiological mechanisms, occurs in a harmonious manner throughout the body. However, the presence of some deleterious factors such as surgery, trauma or pathology, can interfere with the physiology of bone remodeling. It´s Known that the synergistic antimicrobial action between drugs and biomaterials can help and favor osteogenesis after grafting surgery. Therefore, this study aims to develop chitosan / hydroxyapatite scaffolds with amoxicillin for bone repair in the oral cavity. For this, raw materials were selected and characterized and scaffolds were made by the processes of solubilization, dispersion and lyophilization. The characterizations were made by optical microscopy, scanning electron microscopy, eenergy dispersive spectrometer, swelling potential, degradation analysis, apparent porosity test and in vitro cell cytotoxicity. The scaffolds produced in this research showed to have not only adequate physical characteristics but also chemical and biological ones. It was as well as detected a reproducible methodology that resulted in a biomaterial with morphology that provided a high degree of swelling, porosity, satisfactory degradation and the presence of amoxicillin which was confirmed by the eenergy dispersive spectrometer. Nevertheless, the scaffolds with 30% hydroxyapatite showed the best results for in vitro cell viability. So, it is possible to conclude that the scaffolds produced show successful characteristics for bone repair in the oral cavity.
Developing a Scaffolded, Structured Approach to Road Safety Education in Schools
Authors: Horsnell Graeme , Senserrick Teresa , Twisk Divera
Published: May 2021

Scaffolding is a well-established approach to education to maximise student learning outcomes. The premise of this paper is that there is a need for formal, scaffolded road safety education (RSE) which can be delivered in schools in Australasia. This paper supports the education system as being expert in matching human growth and developing scaffolds on which to build learning stages and presents arguments to show that an RSE scaffold can and should be drawn up. Schools can provide a structured in-class and real world learning experiences within that scaffold, which, with suitable communication, can be backed up by the home and the broader community. An integrated RSE scaffold across primary through secondary schooling is currently lacking in Australasia, but could be readily integrated in current school curricula. This paper calls for such developments and welcomes further debate and implementation of next steps to achieve this.
Death and Injury in Motorcycle Accidents: The Utilisation of Technology to Reduce Risk.
Authors: Evans Vaughan
Published: May 2021

In the early 1970s in Great Britain, the fatality rate for motorcyclists was twenty times that for a car driver, this relative risk has widened to around fifty in modern times. Motorcycling has not become more hazardous, rather a modest decline in the fatality rate over four decades has been eclipsed by a considerably greater reduction in the rate for car drivers. Travel by car has become safer, with seatbelts, a rigid safety cell and crumple zones, airbags, head restraints, energy-absorbing steering wheels, and shatter-resistant windscreens, all contributing to risk reduction. A motorcyclist, conversely, on most modern machines, has none of these features, with the crash helmet being the only safety feature generally adopted by motorcyclists over the last half century. The risk inherent in motorcycling could be reduced to a similar level as car travel by a radical re-design of the motorcycle to include a rigid safety cell, clad in energy absorbing deformable material, coupled with a rider restraint system. Less radical technological changes that could reduce the risk of injury, or death, include fitted anti-lock braking systems, ideally with integrated stability control, and an integral impact-activated airbag may arrest the forward motion of a rider in frontal impact conditions. The relatively simple measure of increased rider and/or machine conspicuousness can reduce the risk of certain accidents.
Teröristlerin İadesi Davalarında Politik Suç İstisnası Sorunsalı ve Türkiye’nin Durumu
Authors: ERHAN Zeynep
Published: May 2021

Türkiye’deki son durum, birçok devlet gibi Türkiye’nin de teröristlerin iadesi konusunda sorun yaşadığını ve diğer devletler tarafından yeterince desteklenmediğini göstermektedir. Teröristlerin iadesine ilişkin sözleşmelerin birçoğu, terör suçlularının iadesine yönelik politik suç istinası getirmektedir. Bu yöndeki düzenlemeler terörle mücadeleye birçok açıdan engel teşkil etmektedir. Teröristlerin iadesi davaları, bu alanda düzenlenen uluslararası sözleşmelerin zayıflığından dolayı da çıkmaza girmektedir ve uzamaktadır. Başka bir deyişle, uluslararası düzenlemelerin eksikliği ve tutarsızlığı, iade talep eden ve talep edilen devlet arasındaki iade sürecini karmaşıklaştırmaktadır. Bu çalışma, teröristlerin iadesi konusunu, Birleşmiş Milletler Güvenlik Konseyi kararları, Türkiye’nin iç hukuku ve uluslararası sözleşmeler ışığında inceleyecektir. Giriş bölümünde teröristlerin iadesi davaları ile ilgili ana sorunlar sunulduktan sonra, ulusal ve uluslararası yasal düzenlemeler altında ayrıntılı bir analiz yapılacaktır.
DIGITAL GAME ADDICTİON, SOCIAL ANXIETY AND ALEXITHYMIA IN ADOLESCENTS
Authors: YILDIRIM Maksude , BAŞDAŞ Öznur
Published: May 2021

This study was planned as a descriptive study in order to research the digital game addiction, social anxiety, and alexithymia levels of adolescents. This research was conducted with 626 adolescents in the age group of 12-15 years. The data were collected using Descriptive Characteristics Form, DGAS-7 (Digital Game Addiction Scale), SAS-A (Social Anxiety Scale for Adolescents), AQC (Alexithymia Questionnaire for Children). It can be asserted in accordance with the data that digital game addiction level was high in the adolescents who were male, played strategy games, and used internet for more than three hours a day. The adolescents, who were aged between 14-15 years and had high socio-economic level, smartphone, internet in their smartphones, and no health problem, experienced more social anxiety and the adolescents, who had low socio-economic level, a high year-end success score, and health problems, showed more alexithymic personality characteristics.
Multi-Stripe Seismic Assessment of Precast Industrial Buildings With Cladding Panels
Authors: Gajera Krunal , Dal Lago Bruno , Capacci Luca , Biondini Fabio
Published: May 2021

Following the empirical observation of widespread collapses of cladding panel connections of precast industrial buildings under recent seismic events, new design solutions have been developed in the framework of the European project SAFECLADDING, including isostatic systems effectively decoupling the seismic response of frame structure and cladding panels. The present paper is aimed at evaluating the seismic response and vulnerability of precast frame structures employing pendulum, cantilever, and rocking cladding connection systems. Within the framework of the research project RINTC–Implicit seismic risk of code-conforming structures funded by the Italian Civil Protection Department within the ReLUIS program, the seismic performance of a typical precast industrial building has been assessed with a probabilistic approach based on the results of static and multi-stripe dynamic non-linear analyses. The seismic vulnerability assessment of each structural system has been carried out with reference to life safety and damage limit states considering three sites of increasing seismic hazard in Italy. The effect of distributed panel mass modeling vs. more common lumped mass modeling has been analyzed and critically commented based on the results of demand over capacity (D/C) ratios. Moreover, biaxial seismic D/C ratios have been evaluated for realistic strong hinge connections for cladding panels.
The Lack of a Representative Tendinopathy Model Hampers Fundamental Mesenchymal Stem Cell Research
Authors: Meeremans Marguerite , Van de Walle Gerlinde R. , Van Vlierberghe Sandra , De Schauwer Catharina
Published: May 2021

Overuse tendon injuries are a major cause of musculoskeletal morbidity in both human and equine athletes, due to the cumulative degenerative damage. These injuries present significant challenges as the healing process often results in the formation of inferior scar tissue. The poor success with conventional therapy supports the need to search for novel treatments to restore functionality and regenerate tissue as close to native tendon as possible. Mesenchymal stem cell (MSC)-based strategies represent promising therapeutic tools for tendon repair in both human and veterinary medicine. The translation of tissue engineering strategies from basic research findings, however, into clinical use has been hampered by the limited understanding of the multifaceted MSC mechanisms of action. In vitro models serve as important biological tools to study cell behavior, bypassing the confounding factors associated with in vivo experiments. Controllable and reproducible in vitro conditions should be provided to study the MSC healing mechanisms in tendon injuries. Unfortunately, no physiologically representative tendinopathy models exist to date. A major shortcoming of most currently available in vitro tendon models is the lack of extracellular tendon matrix and vascular supply. These models often make use of synthetic biomaterials, which do not reflect the natural tendon composition. Alternatively, decellularized tendon has been applied, but it is challenging to obtain reproducible results due to its variable composition, less efficient cell seeding approaches and lack of cell encapsulation and vascularization. The current review will overview pros and cons associated with the use of different biomaterials and technologies enabling scaffold production. In addition, the characteristics of the ideal, state-of-the-art tendinopathy model will be discussed. Briefly, a representative in vitro tendinopathy model should be vascularized and mimic the hierarchical structure of the tendon matrix with elongated cells being organized in a parallel fashion and subjected to uniaxial stretching. Incorporation of mechanical stimulation, preferably uniaxial stretching may be a key element in order to obtain appropriate matrix alignment and create a pathophysiological model. Together, a thorough discussion on the current status and future directions for tendon models will enhance fundamental MSC research, accelerating translation of MSC therapies for tendon injuries from bench to bedside.
Proving the Correctness of Knowledge Graph Update: A Scenario From Surveillance of Adverse Childhood Experiences
Authors: Brenas Jon Haël , Shaban-Nejad Arash
Published: May 2021

Knowledge graphs are a modern way to store information. However, the knowledge they contain is not static. Instances of various classes may be added or deleted and the semantic relationship between elements might evolve as well. When such changes take place, a knowledge graph might become inconsistent and the knowledge it conveys meaningless. In order to ensure the consistency and coherency of dynamic knowledge graphs, we propose a method to model the transformations that a knowledge graph goes through and to prove that the new transformations do not yield inconsistencies. To do so, we express the knowledge graphs as logically decorated graphs, then we describe the transformations as algorithmic graph transformations and we use a Hoare-like verification process to prove correctness. To demonstrate the proposed method in action, we use examples from Adverse Childhood Experiences (ACEs), which is a public health crisis.
The Effects of Curcumin on Diabetes Mellitus: A Systematic Review
Authors: Marton Ledyane Taynara , Pescinini-e-Salzedas Laís Maria , Camargo Maria Eduarda Côrtes , Barbalho Sandra M. , Haber Jesselina F. dos Santos , Sinatora Renata Vargas , Detregiachi Claudia Rucco Penteado , Girio Raul J. S. , Buchaim Daniela Vieira , Cincotto dos Santos Bueno Patricia
Published: May 2021

Diabetes mellitus (DM) is an ensemble of metabolic conditions that have reached pandemic proportions worldwide. Pathology’s multifactorial nature makes patient management, including lifelong drug therapy and lifestyle modification, extremely challenging. Currently, there is growing evidence about the effectiveness of using herbal supplements in preventing and controlling DM. Curcumin is a bioactive component found Curcuma longa, which exhibits several physiological and pharmacological properties such as antioxidant, anti-inflammatory, anticancer, neuroprotective, and anti-diabetic activities. For these reasons, our objective is to systematically review the effects of Curcuma longa or curcumin on DM. Databases such as PUBMED and EMBASE were searched, and the final selection included sixteen studies that fulfilled the inclusion criteria. The results showed that curcumin’s anti-diabetic activity might be due to its capacity to suppress oxidative stress and inflammatory process. Also, it significantly reduces fasting blood glucose, glycated hemoglobin, and body mass index. Nanocurcumin is also associated with a significant reduction in triglycerides, VLDL-c, total cholesterol, LDL-c, HDL-c, serum C reactive protein, and plasma malonaldehyde. Therefore, it can be considered in the therapeutic approach of patients with DM.
Efficacy of Feedforward and LSTM Neural Networks at Predicting and Gap Filling Coastal Ocean Timeseries: Oxygen, Nutrients, and Temperature
Authors: Contractor Steefan , Roughan Moninya
Published: May 2021

Ocean data timeseries are vital for a diverse range of stakeholders (ranging from government, to industry, to academia) to underpin research, support decision making, and identify environmental change. However, continuous monitoring and observation of ocean variables is difficult and expensive. Moreover, since oceans are vast, observations are typically sparse in spatial and temporal resolution. In addition, the hostile ocean environment creates challenges for collecting and maintaining data sets, such as instrument malfunctions and servicing, often resulting in temporal gaps of varying lengths. Neural networks (NN) have proven effective in many diverse big data applications, but few oceanographic applications have been tested using modern frameworks and architectures. Therefore, here we demonstrate a “proof of concept” neural network application using a popular “off-the-shelf” framework called “TensorFlow” to predict subsurface ocean variables including dissolved oxygen and nutrient (nitrate, phosphate, and silicate) concentrations, and temperature timeseries and show how these models can be used successfully for gap filling data products. We achieved a final prediction accuracy of over 96% for oxygen and temperature, and mean squared errors (MSE) of 2.63, 0.0099, and 0.78, for nitrates, phosphates, and silicates, respectively. The temperature gap-filling was done with an innovative contextual Long Short-Term Memory (LSTM) NN that uses data before and after the gap as separate feature variables. We also demonstrate the application of a novel dropout based approach to approximate the Bayesian uncertainty of these temperature predictions. This Bayesian uncertainty is represented in the form of 100 monte carlo dropout estimates of the two longest gaps in the temperature timeseries from a model with 25% dropout in the input and recurrent LSTM connections. Throughout the study, we present the NN training process including the tuning of the large number of NN hyperparameters which could pose as a barrier to uptake among researchers and other oceanographic data users. Our models can be scaled up and applied operationally to provide consistent, gap-free data to all data users, thus encouraging data uptake for data-based decision making.
Age, Initial Central Retinal Thickness, and OCT Biomarkers Have an Influence on the Outcome of Diabetic Macular Edema Treated With Ranibizumab– Tri-center 12-Month Treat-and-Extend Study
Authors: Lai Chun-Ting , Hsieh Yi-Ting , Lin Chun-Ju , Wang Jia-Kang , Lin Chih-Ying , Hsia Ning-Yi , Bair Henry , Chen Huan-Sheng , Chiu Chiung-Yi , Weng Shao-Wei
Published: May 2021

Objective: We report the tri-center 1-year outcomes of a treat-and-extend (T&E) regimen in four-week intervals with ranibizumab for diabetic macular edema (DME).

Methods: In this retrospective study, all eyes received 3 monthly loading injections of 0.5 mg ranibizumab, followed by a T&E regimen for DME. Regression models were used to evaluate the associating factors for visual and anatomical outcomes.

Results: Ninety one eyes from 64 patients were enrolled. Mean LogMAR best-corrected visual acuity (BCVA) improved from 0.58 at baseline to 0.36 at month 12 and mean central retinal thickness (CRT) decreased from 411 μm at baseline to 290 μm at month 12. Younger age and eyes having thinner baseline CRT, with ellipsoid zone disruption (EZD), and without epiretinal membrane (ERM) were associated with better final CRT. Moreover, eyes with thicker baseline CRT tend to receive more injections. Among the parameters, only having ERM or EZD was associated with significant BCVA recovery.

Conclusions: A T&E regimen with ranibizumab by 4-week intervals is effective in improving BCVA and reducing CRT with efficacy notable starting from the third month. Clinical parameters including age, initial CRT, and presence of ERM or EZD significantly influenced therapeutic outcomes. Moreover, the presence of ERM should not preclude DME patients from receiving anti-VEGF therapy. Future studies with larger cohorts are warranted.