bluuebunny/crossref_metadata_2025 huggingface dataset:
Utilizing gene expression profiling for the identification of small cell lung cancer subtypes
Authors: Huang Chao , Fu Kai
Published: November 2024

Abstract. Small cell lung cancer is a highly aggressive form of lung cancer associated with poor prognosis and limited treatment options. Gene expression profiling has emerged as a valuable tool for classifying SCLC into distinct molecular subtypes, each with its own unique therapeutic vulnerabilities and biomarkers. Recent studies have identified four primary subtypes: SCLC-A, SCLC-N, SCLC-P, and SCLC-Y, with additional classification into neuroendocrine (NE) high, NE-low, and non-NE tumors. Advanced understanding of the molecular characteristics of these subtypes presents new opportunities for targeted therapeutic approaches. The paper underscores the potential for a shift toward personalized therapy for SCLC, taking into account the inter- and intratumoral heterogeneity and dynamic subtype interconversion in response to treatment. Incorporating subtype-specific biomarkers in clinical trial designs could lead to the first-ever molecular biomarker-driven approach in the management of SCLC, greatly enhancing treatment effectiveness and patient outcomes.
The relation between cerebral morphological abnormalities in major depressive disorder and antidepressant treatment
Authors: Sun Yaya
Published: November 2024

Abstract. The cerebral morphological abnormalities caused by Major Depressive Disorder (MDD) are markedly different from those of many other cerebral parts in non-patients. This brain disorder may be coordinated by antidepressant treatment. This paper investigates the links between antidepressant medication and morphological features in MDD using a literature review method. The paper finds that there is a positive response and feedback on these neurobiological alterations. The relationship between morphological features and treatment may make it easier to objectively observe the effects of antidepressants on MDD patients. The review emphasizes the importance of understanding the cerebral morphological changes associated with MDD, as well as how antidepressant therapy can potentially modulate these alterations. By exploring the relationship between pharmacological interventions and structural brain changes, the paper provides insights into the neurobiological mechanisms underlying the therapeutic effects of antidepressants. This knowledge can enhance the advancement of more focused and efficient therapy approaches for patients with Major Depressive Disorder.
Analisis Manajemen Konstruksi Pada Pembangunan Ruas Jalan Rate-Rate Dalam Kota
Authors: Nuhun Ridwan Syah , Soeparyanto Try Sugiyarto , Sutrayasa Gede Agus , Deny Laode , Ramadan Kadir , Sulistyo Galih Adi
Published: November 2024

Road infrastructure development is an important factor in supporting economic growth and community mobility in urban areas. However, road construction in urban areas is often faced with various challenges, such as limited space, population density and the dynamics of community activities. This requires effective and efficient construction management to ensure the smoothness and success of the project. The aim of this research is to find out how cost calculations are carried out using AHSP and also to find out how to carry out and time schedule construction work for inner city lane roads. The method for implementing the construction of lane roads in the city is in the form of asphalting roads with a length of 3.06 KM and a duration of 90 days. The budget plan for building a 3.6 KM inner-city toll road is IDR. 10,428,920,000.
Perbandingan Kinerja Marshall Pada Campuran Aspal AC-WC Menggunakan Plastik Polypropilene (PP) Dan Plastik High Density Polyethylene (HDPE)
Authors: T Nurfadila , Mustakim Mustakim , Fadly Imam
Published: November 2024

According to the Ministry of Environment and Forestry, Indonesian people produce 0.8 kg of waste per person per day, of which 15% is plastic waste or equivalent to 189,444,000 tons of waste per day 8, Therefore, the amount of waste must be proportional to the proportion of waste processed and the rest must not be disposed of and pollute the environment. The types of plastics used in this study were Polypropylene (PP) Plastic and High Density Polyethylene (HDPE) Plastic. The purpose of this study was Determination of Melshell performance in AC- WC asphalt mixture without the addition of polypropylene (PP) plastic and high density polyethylene plastic (HDPE). The research method used was experimental with variations of 2%, 4%, and 6%, from the weight of KAO asphalt. Marshall comparison results AC-WC asphalt using polypropylene (PP) and high density polyethylene (HDPE) resins, with only VMA and MQ stable values meeting the 2018 Development Specifications while VFA, VIM and FLOW do not meet the specifications
PENGARUH KUALITAS PELAYANAN TERHADAP KEPUASAN KONSUMEN PADA INDOMARET DI KECAMATAN MOLAWE KABUPATEN KONAWE UTARA
Authors: Rahmawati Rahmawati , Sahyunu Sahyunu , Manan Laode Abdul
Published: November 2024

Seiring dengan berjalannya waktu persaingan di dunia bisnis semakin pesat di era globalisasi pasar bebas. Beragam inovasi terus menerus muncul dari waktu ke waktu dengan memanfatkan teknologi yang semakin canggih. Dalam proses berjalannya suatu bisnis tentunya tidak lepas dari kepuasan konsumen, kepuasan konsumen memegang peran penting dalam menilai Tingkat kualitas yang dimiliki suatu perusahaan sehingga salah satu kunci dari kesuksesan dan tingginya kualitas perusahaan adalah kepuasan konsumen. Penelitian ini bertujuan untuk mengetahui pengaruh kualitas pelayanan terhadap kepuasan konsumen pada indomaret di Kecamatan Molawe Kabupaten Konawe Utara. Penentuan jumlah responden dalam penelitian ini menggunakan purposive sampling dimana jumlah sample pada penelitian ini adalah 70 responden. Hasil penelitian ini menunjukan bahwa kualitas pelayanan berpengarih positif namun tidak signifikan terhadap kepuasan konsumen pada indomaret di kecamatan molawe kabupaten konawe utara
Information Acquisition Costs and Analysts’ Cash Flow Forecasts: The Role of Management Cash Flow Forecasts
Authors: He Ting , Imhof Michael , Zheng Kenneth
Published: November 2024

We examine whether the provision of managerial cash flow forecasts is a significant predictor of analysts’ decision to cover a firm with cash flow forecasts. Unlike managerial earnings forecasts, which are often issued to walk down analyst earnings estimates, managers issue cash flow forecasts to counter bad earnings news and lessen the cost of investor and analyst information acquisition (Wasley & Wu, 2006). Motivated by the increasing popularity of managerial cash flow forecasts and prior empirical evidence that analysts are less likely to follow a firm for which the costs of acquiring financial information are prohibitive (e.g., Liu, 2011), we predict and find that the provision of managerial cash flow forecasts is a significant determinant of the likelihood of analyst cash flow coverage. We also find that analysts are less likely to issue cash flow forecasts when the effort necessary to follow a firm is high. Together, the evidence suggests that the existence of management cash flow forecasts is an important determinant of analysts’ cash flow coverage.
Understanding the Different Functions of Transitive Verbs and Intransitive Verbs and Related Problems from the Teachers’ Point of View
Authors: Tahan Jaradat Abeer Fawzi
Published: November 2024

The process of acquiring grammar requires distinguishing between parts of the sentence, including the verb and the subject, as well as the ability to form the verb and distinguish the best verb forms. This study aims to understand the different functions of transitive verbs and intransitive verbs and the problems related to them. The quantitative descriptive approach was used in this study by using a questionnaire (questionnaire) designed by the researcher to evaluate teachers’ perceptions towards the different functions of transitive verbs, intransitive verbs, and related problems. This study concluded that the main function of transitive and intransitive verbs is to develop the communication process level by guaranteeing delivering the exact correct meaning of sentences. The study also clarified that several difficulties could be faced when distinguishing transitive and intransitive verbs, such as creating incomplete and dysfunctional sentences, making grammatical errors, and generating mistakes in the employment and formulation of these verb types.
Dampak Unggahan Akun Instagram @Giladiskon terhadap Minat Beli Remaja
Authors: Amalia Diana , Ardiputra Hadyan , Septiani Laras
Published: November 2024

Latar belakang studi ini berakar pada munculnya sejumlah akun diskon yang serupa dalam waktu belakangan ini. Akun-akun diskon di platform Instagram berpotensi untuk membantu masyarakat, terutama para pengikutnya, dalam mencari penawaran diskon di Indonesia secara efisien. Kehadiran diskon tersebut juga berkontribusi pada perubahan gaya hidup masyarakat, di mana adanya penawaran diskon dapat meningkatkan kemampuan beli terhadap produk. Fenomena ini dapat mempengaruhi terbentuknya niat pembelian sehingga berdasarkan fenomena tersebut, terdapat kemungkinan adanya efek kecenderungan membeli. Teori yang diterapkan dalam studi ini mencakup teori pengaruh penampilan, teori minat, dan teori S-O-R. Metodologi penelitian yang digunakan adalah pendekatan kuantitatif yang menerapkan analisis hubungan sebab-akibat. Hasil dari analisis kuantitatif tersebut disajikan dalam bentuk data lapangan dengan menggunakan teknik analisis regresi linier sederhana. Hasil analisis data mengindikasikan bahwasanya unggahan dari akun @giladiskon di platform media sosial Instagram memiliki dampak signifikan terhadap niat beli remaja di Surabaya. Pasalnya, semakin tinggi frekuensi, durasi, dan intensitas postingan iklan di Instagram, maka semakin besar pula dampaknya terhadap niat membeli.
Peranan Gaya Hidup dan Content Marketing dalam Meningkatkan Keputusan Pembelian Konsumen
Authors: Nataatmadja Vandy Satria , Tjiptodjojo Kartika Imasari
Published: November 2024

Kemajuan teknologi, informasi, dan komunikasi telah mengubah secara fundamental cara kita berkomunikasi dan menjalani gaya hidup kita. Marketplace berperan penting sebagai penghubung produsen dan konsumen guna melakukan transaksi secara online. Populasi yang ditentukan yaitu, Masyarakat di Kota Bandung yang menggunakan marketplace sebagai media berbelanja, serta sampel nya Masyarakat di Kota Bandung yang menggunakan marketplace Shopee sebagai media berbelanja. Pengaruh gaya hidup secara parsial tidak memiliki pengaruh terhadap keputusan pembelian pelanggan marketplace Shopee di Kota Bandung sedangkan content marketing memiliki pengaruh secara parsial pada keputusan pembelian pelanggan marketplace Shopee di Kota Bandung. Lalu, secara simultan gaya hidup dan content marketing memiliki pengaruh sebesar 40% pada keputusan pembelian pelanggan marketplace Shopee di Kota Bandung.
Implementasi Pengembangan Kurikulum Merdeka pada Mata Pelajaran Al-Qur’an dan Hadis di Madrasah Aliyah Negeri
Authors: Billah Muhammad Afrizal Sauqi , Achadi Muh Wasith
Published: November 2024

Penelitian bertujaun untuk mengetahui Implementasi Kurikulum Merdeka pada mata pelajaran Al-Quran dan Hadist pada MAN 2 Sleman. Metode penelitian yang digunakan dalam penelitian ini yaitu metode penelitian kualitatif dengan pendekatan studimlapangan, sehingga penelitian ini dapat menggali pengalaman guru dan peserta didik dalam menghadapi perubahan kurikulum. Data dikumpulkan melalui observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa Konsep dan implementasi kurikulum Merdeka Belajar di MAN 2 Sleman telah diterapkan dengan baik dan sesuai dengan aturan dalam pendidikan Kurikulum Merdeka. Implementasi kurikulum ini akan memberikan siswa lebih banyak kesempatan untuk berpartisipasi dalam pembelajaran. Program ini berfokus pada pengembangan pola pikir siswa dalam berpikir kritis dan inovasi.  Guru memerankan penting dalam proses mengajar, terutama dalam mata pelajaran Al-Qur'an dan Hadits.  Guru menerapakan proses pembelajaran sesuai dengan karakteristik siswa, sehingga dapat meningkatan hasil belajar siswa pada penerapan Kurikulum Merdeka. Namun, dalam penerapan ini guru memiliki hambatan dalam prosesnya yaitu tidak adanya bahan ajar (buku) sebagai modul pembelajaran. Dengan demikian, studi ini menunjukkan perlunya dukungan yang lebih besar dari berbagai pihak, termasuk pemerintah, sekolah, dan masyarakat, agar Kurikulum Merdeka tersebut dapat terlaksana dengan baik. Diperlukan penelitian lebih lanjut untuk mengidentifikasi faktor-faktor lain yang memengaruhi Implementasi Kurikulum Merdeka, sehingga dapat meningkatkan penerapan kurikulum merdeka melalui pengembangan strategi yang diterapkan pada sekolah-sekolah lainnya.
Kajian Psikolinguistik: Gangguan Berbahasa dalam Film “Miracle in Cell No.7” Serta Relevansinya pada Pembelajaran Inklusi di Sekolah
Authors: Wulan Siti Yulia Ambar , Salamah Salamah , Romadhianti Rona
Published: November 2024

Penelitian ini mengkaji gangguan berbahasa pada tokoh utama penyandang disabilitas intelektual dalam film “Miracle In Cell No. 7” versi Indonesia. Metode penelitian ini adalah deskriptif kualitatif. Metode penelitian deskriptif kualitatif adalah suatu metode penelitian yang digunakan untuk meneliti situasi pada objek yang alamiah serta hasil penelitian kualitatif lebih menekankan makna dari pada penalaran. Teknik pengumpulan data dilakukan dengan pengamatan film, transkip dialog dan menganalisis isi yang berkaitan dengan gangguan berbahasa yang dialami oleh tokoh utama. Analisis data dalam penelitian ini menggunakan kajian psikolinguistik dengan teori Scovel. Sumber data penelitian ini yaitu, sumber data primer melalui film “Miracle In Cell No. 7” versi Indonesia dan sumber data sekunder melalui berbagai macam literatur yang berkaitan dengan objek penelitian seperti penelitian terdahulu. Penelitian ini bertujuan untuk mendeskripsikan gangguan berbahasa pada tokoh utama individu disabilitas intelektual dalam film “Miracle In Cell No. 7” versi Indonesia yang mengalami keterbatasan pada kemampuan kognitif dan fungsi adaptif. Hasil temuan pada penelitian ini berjumlah 12 data yang menunjukkan adanya gangguan berbahasa pada tokoh utama dalam film “Miracle In Cell No. 7” versi Indonesia yang telah dianalisis berdasarkan teori Scovel berupa empat tahapan dalam produksi bahasa yaitu konseptualisasi, formulasi, artikulasi dan pemantauan diri. Penelitian ini berkontribusi terhadap dunia pendidikan yang dapat di gunakan guru sebagai salah satu bahan ajar terutama pada materi pelajaran bahasa Indonesia di sekolah.
Peran Guru dalam Mengatasi Perilaku Perundungan (Bullying) terhadap Siswa
Authors: Gea Yulirman , Lase Fatiani , Harefa Amstrong , Hulu Syukur Kasieli
Published: November 2024

Tujuan penelitin ini untuk mengetahui peran guru dalam mengatasi perundungan (bullying) terhadap siswa di SMP Negeri 1 Tuhemberua, serta mengetahui kendala dan upaya mengatasi perundungan (bullying) terhadap siswa di SMP Negeri 1 Tuhemberua. Hasil penelitian dan pembahasan disimpulkan bahwa: pertama memberikan konseling kepada siswa yang korban perundungan, artinya mereka mengatasi dampak emosional, dan meningkatkan rasa percaya diri mereka, dan Guru juga sangat berperan penting dalam menciptakan suasana kelas yang inklusif dan positif, serta memberikan pendidikan tentang perundungan secara konsisten. Kedua kendala yang di hadapi oleh guru dalam mengatasi perundungan (bullying) terhadap siswa kurangnya dukungan dari orang tua menjadi hambatan dalam penanganan kasus perundungan, kemudian perundungan sering terjadi di tempat-tempat yang sulit diawasi, dan ada kesulitan dalam membedakan antara bercanda dan perundungan yang sebenarnya. menyediakan jalur pelaporan anonim, dan melibatkan orang tua. Dan ada beberapa area yang ditingkatkan, seperti memperbanyak kegiatan yang melibatkan siswa secara langsung, memperketat penegakan aturan, meningkatkan pengawasan di area rawan perundungan, serta memberikan edukasi lebih intensif kepada orang tua. Ketiga upaya mengatasi kendala yang dihadapi oleh guru dalam mengatasi perilaku perundungan (bullying) terhadap siswa adalah menyediakan jalur pelaporan anonim, dan melibatkan orang tua. Serta beberapa area yang ditingkatkan, seperti memperbanyak kegiatan yang melibatkan siswa secara langsung, memperketat penegakan aturan, meningkatkan pengawasan di area rawan perundungan, serta memberikan edukasi lebih intensif kepada orang tua.
Analisis Penerapan Strategi Diskusi Kelompok dalam Berpikir Kritis Siswa terhadap Pembelajaran Pendidikan Pancasila dan Kewarganegaraan
Authors: Mendrofa Sudiaman , Harefa Hendrikus Otniel Nasozaro , Harefa Anugerah Tatema , Lase Berkat Persada
Published: November 2024

Penelitian ini bertujuan untuk mengetahui penerapan strategi diskusi kelompok dalam berfikir kritis siswa terhadap pembelajaran Pancasila dan Kewarganegaraan di SMP Negeri 2 Hiliduho. Jenis penelitian yang digunakan adalah penelitian kualitatif dalam penelitian ini. informasi dikumpulkan melalui observasi dan wawancara. Teknik reduksi data, visualisasi data, dan penarikan kesimpulan digunakan untuk menganalisis data. Melalui diskusi kelompok siswa dapat lebih aktif dalam mengikuti pembelajaran, dengan cara membagi kelas menjadi kelompok-kelompok kecil beranggota 5 orang setiap satu kelompok, ini dapat mendorong siswa aktif dalam diskusi dengan bertanya pertanyaan terbuka. Kemudian kendala-kendala yang didapatkan dalam penerapan stratergi diskusi kelompok, seperti ada beberapa siswa mungkin tidak memiliki keterampilan komunikasi dan berpikir kritis yang di perlukan untuk berpartisipasi secara efektif dalam diskusi kelompok, dan kelas yang tidak terorganisir dengan baik dapat membuat sulit untuk membagi siswa menjadi kelompok untuk diskusi, dan ada satu dua orang anggota kelompok yang mendominasi diskusi, sehingga anggota lain merasa sulit menyampaikan pendapat mereka, seperti kurang memberikan tanggapan/saran, jarang berbicara dalam kelompok, lebih banyak diam dan upaya untuk mengatasi kendala-kendala tersebut yaitu Guru memberikan pelatihan kepada siswa tentang keterampilan berpikir kritis seperti menganalisis informasi melalui kegiatan pemecahan masalah, analisis teks, dan debat. Guru juga memfasilitasi kegiatan yang mendorong siswa untuk berkomunikasi secara efektif dan berkolaborasi dengan anggota kelompok lainnya, kegiatan ini dapat di lakukan melalui presentasi kelompok dan diskusi terbuka.
Efektivitas Video Animasi terhadap Pemahaman Konsep Matematis Peserta Didik Sekolah Dasar
Authors: Widianingsih Diah , Widyaningtius Negi Titin , Melinda Resti Umi , Supriyadi Supriyadi , Hermawan Jody Setya
Published: November 2024

Masalah dalam penelitian ini terlihat masih rendahnya pemahaman konsep matematis pada peserta didik kelas IV sekolah dasar karena pendidik di sekolah belum menggunakan media yang bervariasi untuk mendukung dalam proses pembelajaran yang berlangsung. Penelitian ini bertujuan untuk mengetahui efektivitas media interaktif berbasis video animasi terhadap pemahaman konsep matematis. Metode yang digunakan yaitu pre experimental dengan one grup pretes-postest design.populasi pada penelitian ini berjumlah 15 peserta didik yang tergabung dalam bimbingan belajar Omah Privat. Hasil penelitian menunjukan bahwa hasil uji N-gain sebesar 0,64 dengan hasil sig 0,64 >0,05 yang menunjukan bahwa terdapat peningkatan kemampuan pemahaman konsep matematis peserta didik dengan kategori sedang.
Pengaruh Lingkungan Sekolah terhadap Pembantukan Karakter Peserta Didik Kelas V
Authors: Maloring Maksima Regina Marian , Dewi Lismawati , Putri Dita Febrina , Supriyadi Supriyadi , Izzatika Amrina
Published: November 2024

Pengaruh lingkungan sekolah terhadap pembentukan karakter siswa sangat penting terutama pada kelas lima, yang merupakan tahap kunci dalam pertumbuhan sosial dan emosional. Penelitian ini bertujuan untuk menilai pengaruh lingkungan sekolah terhadap pembentukan karakter siswa di SDN Gotong Royong, yang berlokasi di Kota Bandar Lampung. Metode kuantitatif dengan pendekatan deskriptif korelasional digunakan, melibatkan 36 siswa yang mengisi kuesioner, dengan analisis data dilakukan menggunakan SPSS versi 27. Hasil penelitian menunjukkan adanya korelasi yang signifikan dan positif antara lingkungan sekolah dengan pembentukan karakter, ditunjukkan oleh koefisien korelasi Pearson sebesar 0.699 dan nilai R Square sebesar 0.489. Ini menunjukkan bahwa 48,9% variasi dalam pembentukan karakter dipengaruhi oleh lingkungan sekolah. Uji hipotesis menghasilkan nilai t sebesar 5.703, melebihi nilai t-tabel sebesar 2.032, yang mengonfirmasi hubungan yang bermakna antara kedua variabel tersebut. Kesimpulannya, lingkungan sekolah sangat memengaruhi pembentukan karakter siswa kelas lima di SDN Gotong Royong.
Strategi Pemasaran Usaha Gula Aren Di Desa Baturappe Kecamatan Biring Bulu Kabupaten Gowa
Authors: Sumarlin K Andi , Rachmawaty Rachmawaty
Published: November 2024

Penelitian ini bertujuan untuk menganalisis strategi pemasaran usaha gula aren di Desa Baturappe, Kecamatan Biring Bulu, Kabupaten Gowa. memiliki potensi yang besar untuk dikembangkan sebagai salah satu produk unggulan lokal. Gula aren merupakan produk yang tidak hanya memiliki nilai ekonomi tinggi, tetapi juga kaya akan manfaat Kesehatan, pemasaran yang efektif sangat diperlukan untuk meningkatkan daya saing produk gula aren di pasar lokal maupun nasional. Pendekatan yang digunakan adalah deskriptif kualitatif dengan mengidentifikasi berbagai faktor yang memengaruhi pemasaran, seperti kualitas produk, harga, distribusi, dan promosi. Data diperoleh melalui wawancara dengan pelaku usaha, observasi langsung, dan studi dokumentasi. Hasil penelitian menunjukkan bahwa pemasaran gula aren di desa ini masih menghadapi tantangan dalam akses pasar yang lebih luas akibat keterbatasan jaringan distribusi dan promosi. Strategi pemasaran yang diusulkan meliputi peningkatan kualitas produk melalui sertifikasi, penetapan harga yang kompetitif, diversifikasi saluran distribusi, serta optimalisasi promosi melalui media sosial dan kerjasama dengan lembaga terkait. Implementasi strategi ini diharapkan dapat meningkatkan daya saing gula aren Desa Baturappe, memperluas jangkauan pasar, dan memberikan kontribusi positif terhadap perekonomian masyarakat setempat. Hasil dari penelitian ini diharapkan dapat memberikan rekomendasi yang berguna bagi pelaku usaha gula aren dalam mengoptimalkan strategi pemasaran mereka.
A Novel Arithmetic Optimization Technique for Electric Vehicle Charging
Authors: B Ashok , Michael Prawin Angel
Published: November 2024

With the increased usage of Electric vehicles in recent days, the optimal usage of battery both in terms of electrical and economic perspective is very important. Though several battery optimization techniques are evolving day by day, the method to achieve an efficient control of all parameters like battery current, power and power loss has not yet been achieved. This paper proposes a novel approach of implementing an arithmetic optimization scheme for FTP 75 drive cycle source. In this connect, the details of the arithmetic operators are discussed and their relations with electrical parameters are framed from the fundamental equations. A Pseudo-code has been developed and implemented for identifying the optimum charging point from different search spaces. The simulation results obtained for different electrical parameters with respect to different arithmetic operators, emphasizes the enhanced operation of electric vehicles at optimum charging points.
ORGANIZATIONAL RESILIENCE AND THE AIRLINE INDUSTRY: A QUALITATIVE STUDY
Authors: Yanıkoglu Özge , Kılıç Sena , Üçler Çağlar
Published: November 2024

Airlines frequently experience several disruptive events that can substantially deviate operations from planned routines, resulting in significant losses. It's crucial for airlines to develop resources and consistently identify opportunities for adaptation to these unpredictable circumstances. Despite predetermined plans for specific situations often exist, there is often a lack of policy-level guidelines for preparing for unknown circumstances— a concept known as resilience policy. This study delves into the constructs of resilience policy by drawing insights from 10 semi-structured interviews conducted with executives from 6 airline companies in Turkey. The findings pinpoint seven key criteria that offer a roadmap for effective policy development: financial management, flexibility and adaptability, effective risk management, strong leadership and culture, talent management, robust IT infrastructure, and collaborative partnerships. These criteria collectively provide a roadmap for developing policies that enhance an airline's ability to manage unexpected disruptions efficiently.
DRONE SELECTION FOR AGRICULTURAL ENTERPRISES WITH INTERVAL TYPE-2 FUZZY COPRAS METHOD
Authors: Oğuz Alparslan
Published: November 2024

Technological advancements have led to changes in unmanned aerial vehicles, just as in all fields. These vehicles, known as drones, are used in many areas such as mapping, logistics, entertainment, and agriculture. Especially in agriculture, drones are widely used for various purposes such as mapping, detecting weeds, fertilization, and spraying. This situation has increased the market volume of drones and many companies have introduced their products for sale. Agriculture plays a significant role in the development of developing countries, and drone technologies are of great importance in increasing sector productivity. Drone technologies provide transparency and traceability in the cultivation process of products. Therefore, the aim of the study is to determine the selection criteria of agricultural drones for agricultural enterprises and to select the most suitable alternative among the alternatives. Nine criteria were determined through literature review and expert opinion. Seven alternatives from two companies selling in Türkiye were evaluated. Alternatives were analyzed using the Interval Type-2 COPRAS method. As a result of the evaluation by three experts, alternative A2 was determined as the most suitable alternative.
BÜTÜNLEŞİK FUCOM-VIKOR YAKLAŞIMIYLA TR-90 BÖLGESİNDE SİLAH ORGANİZE SANAYİ BÖLGESİ YER SEÇİMİ
Authors: Tip Fatma Nur , Peker İskender , Gergin Ramazan Eyüp
Published: November 2024

Çalışmanın amacı, bütünleşik FUCOM-VIKOR yaklaşımı ile TR90 bölgesi için en uygun silah organize sanayi bölgesi yerinin belirlenmesidir. Bu amaç için, ilgili literatür ayrıntılı olarak analiz edilmiş ve yer seçiminde faydalanılan öncü kriterler tespit edilmiştir. Savunma sanayisinin önde gelen firmaları ve uzmanların görüşlerine göre, TR90 bölgesinde yer alan iller çalışmanın alternatifleri olarak belirlenmiştir. Çalışmada kullanılan kriter ağırlıklarının hesaplanmasında FUCOM, alternatiflerin sıralanmasında ise VIKOR yöntemlerinden faydalanılmıştır. Elde edilen sonuçlara göre maliyet faktörü en yüksek önem derecesine sahip ana kriter, sosyo-ekonomik faktörler ise en düşük önem derecesine sahip olan ana kriter olarak belirlenmiştir. VIKOR yönteminden elde edilen bulgular Silah Organize Sanayi Bölgesi için en uygun ilin Trabzon olduğunu göstermektedir.
EXPLOITING LIMITATIONS: EXAMINING THE CONCEPT OF “BRICOLAGE” IN MANAGEMENT STUDIES THROUGH A BIBLIOMETRIC ANALYSIS
Authors: Gerçek Merve
Published: November 2024

Bricolage, a novel concept derived from anthropology, has a significant impact on contemporary management practices by promoting the use of available resources to deal with challenges and exploit resources. Previous research has highlighted the importance of bricolage in encouraging innovative thinking and adaptability in organizations, particularly in developing nations where resources are scarce. Although the notion is very adaptable, researchers could encounter the difficulty of combing through the diverse range of publications to find essential academic sources and articles on management. Therefore, a bibliometric analysis is necessary to thoroughly review and assess current trends in the management literature on bricolage. This study examines the existing literature on bricolage in management studies to identify research trends and potential gaps. The study's sample consisted of 209 publications published between 2003 and March 2024 in the Web of Science database. VOSviewer was used to analyze and display the associations among journals, authors, countries, and keywords. According to the results, bricolage is an important tool for businesses to overcome limitations within the entrepreneurial domain. The findings indicate that the United States, England, and China are significant research hubs in the research network. Also, keyword analysis revealed that a growing body of research is bridging the gap between entrepreneurship and other fields, such as technology, innovation, policy, and society, according to the relationships discovered. This study provides a comprehensive overview of bricolage research in management studies and practical suggestions for researchers, practitioners, and policymakers to enhance the application of bricolage in various organizational and management contexts.
KREDİ KARTLARINDAN YAPILAN NAKİT AVANS İŞLEMLERİYLE BANKALARIN NET KARLILIĞI ARASINDAKİ ETKİLEŞİMİN ANALİZİ: TÜRK BANKACILIK SEKTÖRÜ ÖRNEĞİ
Authors: Keskin Ömer
Published: November 2024

Bu çalışmanın amacı, Türkiye’de kredi kartlarından yapılan nakit avans işlemlerinin tutarıyla bankaların net kar miktarı arasındaki ilişkiyi zaman serisi analiziyle belirlemektir. Veri dönemi, 2015M1-2024M3 aralığını içermektedir. Uygulanan yöntemler arasında; Kesirli-Frekanslı Fourier Artırılmış Dickey-Fuller (KFFADF) birim kök testi, Kesirli-Frekanslı Fourier Otoregresif Gecikmesi Dağıtılmış (KFFADL) eşbütünleşme testi ve Kesirli-Frekanslı Fourier Toda-Yamamoto (KFFTY) nedensellik testi bulunmaktadır. Eşbütünleşme testine göre kredi kartlarından yapılan nakit avans işlem tutarındaki %1 yükseliş, bankaların net kar miktarını uzun ve kısa dönemde sırasıyla %0,88 ve %1,04 kadar yükseltmektedir. Eşbütünleşme testinin bulguları, nedensellik test bulgusuyla desteklenmektedir. Sonuç olarak kredi kartlarıyla yapılan işlemlerin yaygınlaşması, kayıt dışı ekonomiyi azaltıcı bir işlev görmektedir. Bununla birlikte kredi kartlarının bilinçli bir şekilde kullanılması, olası sorunların önüne geçmek açısından önem arz etmektedir.
Subcutaneous Insulin Infusion Versus Multiple Administrations of Insulin Analogs: Is Either Method Associated with Better Quality of Life in Pediatric Patients with Type 1 Diabetes Mellitus?
Authors: Gomes Pereira Cecília , Nogueira Machado Sara , Azevedo Catarina , Delgado Lucinda , Sousa Beatriz , Dias Ângela , Meireles Carla
Published: November 2024

Objectives − Type 1 Diabetes Mellitus (DM1) requires demanding treatment in order to achieve good metabolic control. Our aim was to assess whether either method of insulin administration (multiple daily administrations of insulin analogues (MDIA) or continuous subcutaneous insulin infusion (CSII)) is associated with better health-related quality of life (HRQoL).Methods − We conducted a cross-sectional study. Patients aged 10-18 years with a disease duration of at least six months were included. HRQoL was assessed by having patients and their caregivers complete the DISABKIDS-37 questionnaire.Results − Of the 40 patients included, 22 (55%) had CSII. There were no statistically significant differences between subscale scores and overall HRQoL between patients or between parents of patients with CSII or MDIA. CSII patients and parents scored better on all subscales and on the total scale, although without statistically significant differences. There were no statistically significant differences in the subscale scores and overall HRQoL reported by the patients and their parents, but there was a strong correlation between the children’s and parents’ scores (R=0.770; P<0.01), which was similar in patients with CSII or MDIA (R=0.735 vs R=0.790).Conclusion − Although we did not identify statistically significant differences, there was a trend towards a better HRQoL associated with the use of CSII, both from the perspective of the adolescents and their parents. This could influence therapeutic choice. Consistency between the assessments of adolescents and their carers was observed. The choice between MDIA and CSII should be based on individual preferences in order to optimize the HRQoL of adolescents with DM1.
Adolescents’ Experiences in Managing Type 1 Diabetes
Authors: Lukács Andrea , Debreczeni Edina
Published: November 2024

Objectives − This study examined perceived changes in diabetes management among adolescents with type 1 diabetes as they transition from childhood to adolescence, focusing on self-management, parental involvement, physical activity, and treatment reflections.Patients and Methods − Qualitative description employing individual semi-structured interviews was utilized with 19 adolescents. Interview data were processed using a content analysis approach.Results − Most adolescents managed their diabetes independently, drawing from years of experience. While some adhered to medical advice, others made independent decisions, prioritizing convenience, or habits. Parental roles varied, from regular supervision to granting autonomy. Many adolescents appreciated parental support, feeling it provided security, though some experienced it as overbearing or insufficient. They had increased independence in managing their diabetes as they grew older. Acceptance of the disease improved with time, aided by technological advancements. Challenges included increased insulin needs and food intake during adolescence, but overall, they felt more confident and responsible in self-management. Despite advancements in technology, practical challenges persist in managing diabetes during physical activity.Conclusion − Adolescents with diabetes generally develop effective self-management skills and appreciate increasing autonomy, though adherence to medical advice varies. Continued parental support and advanced diabetes technologies play crucial roles in their management. Personalized treatment and balanced parental involvement are needed to increase adherence.
Acral Peeling Skin Syndrome: A Rare Skin Disorder
Authors: Poço Miranda Sofia , Lopes Magalhães Teresa , Bernardo Diana , Machado Susana
Published: November 2024

Objective − We report the case of an 8-year-old girl with acral peeling skin syndrome.Case Report − A previously healthy 8-yearold girl presented with a history of flaccid bullous lesions on the plantar surface of her feet, and subsequent peeling and scarring since she was 12 months old. A biopsy of the plantar lesion was carried out and histological examination revealed an acral skin flap characterized only by the presence of an intracorneal bullous cleft, with hypogranulosis and focal parakeratosis. A genetic study was carried out, identifying two pathogenic heterozygous variants in the TGM5 gene. The clinical presentation, histological and genetic examination confirmed the diagnosis of acral peeling skin syndrome.Conclusion − Acral peeling skin syndrome is not a widely known pathology, which means that cases of acral peeling skin syndrome can be misdiagnosed as Epidermolysis bullosa simplex, especially when a genetic study is not available. Particularly in younger children, it is important not to underestimate the diagnosis of acral peeling skin syndrome, given the different prognostic implications between the two diagnoses.
Duodenal Atresia with Apple-peel Intestinal Atresia: a Case with Favorable Outcome
Authors: Banjac Lidija , Banjac Boban , Haliti Azem , Majic Velibor
Published: November 2024

Objective − Duodenal atresia with apple-peel intestinal atresia remains a difficult and complex condition, even with advances in medical and surgical therapies. Due to the significant difference in etiology, the association between these two types of atresia is very rare and is associated with a high rate of mortality. Only twelve of these cases have been described so far in English literature, most often with a poor outcome. Our patient survived and is doing well.Case Report − Here, we present a premature infant in whom intestinal atresia was suspected prenatally. On the first day of life, based on clinical, radiographic and ultrasound examination, suspicion was confirmed and surgical intervention was performed. It was discovered that the proximal part of the duodenum blindly ends with a large dilation. The proximal jejunum also ends blindly and the distal small intestine wraps around a single mesenteric vessel in a spiral fashion reminiscent of an “apple-peel.” At the first operation (on the first day of life), a double enterostomy of the proximal duodenum and the proximal jejunum was performed. On the second operation (on day 10), the continuity of the digestive intestine was established by end-to-end duodeno-jejunal anastomosis. Progress in body mass was confirmed during the postoperative period and normal stool was formed on a regular basis.Conclusion − Based on our case, possible reasons for the good outcome of patients with these rare forms of intestinal atresia are prenatal suspicion, early postnatal diagnosis, and early surgical intervention. Further studies should investigate the possibility of a common cause of duodenal atresia and apple-peel atresia to facilitate early diagnosis and early treatment.
ESTRATÉGIAS PEDAGÓGICAS PARA INCLUSÃO DE ALUNOS COM DEFICIÊNCIA INTELECTUAL EM SALAS REGULARES
Authors: Lima Rafael Santos , Mendes Linda Ester Pimentel Ramos , Peres Luciana de Sant’Anna , Oliveira Daiani Betini de , Firmino Christiane Sarti dos Santos , Lorencini Natália Libardi , Lima Fabiana Corrêa Malafaia , Gava Flavia Oliveira Carloto , Alves Monica Santos de Souza , Silva Alex Bitencourt da , Nascimento Leandro Wingler do , Pontes Daiana Marques do Nascimento
Published: November 2024

A educação inclusiva busca garantir o direito de todos os alunos, independentemente de suas condições, a uma educação de qualidade em ambientes regulares de ensino. Entre os desafios dessa modalidade, destaca-se a inclusão de alunos com deficiência intelectual, que exige a adoção de estratégias pedagógicas específicas para promover a participação ativa e o desenvolvimento integral desses estudantes. Este artigo explora as principais barreiras enfrentadas no processo de inclusão escolar e propõe práticas pedagógicas que facilitam a adaptação curricular, uso de tecnologias assistivas, e o desenvolvimento de planos educacionais individualizados (PEIs). Além disso, discute a importância de metodologias ativas, como o ensino colaborativo e a diferenciação pedagógica, que promovem o aprendizado diversificado e inclusivo. A colaboração entre professores regulares e de educação especial e a formação continuada dos docentes também são abordadas como elementos cruciais para o sucesso da inclusão. Conclui-se que, ao integrar essas estratégias, as escolas podem oferecer um ambiente mais inclusivo e eficaz para o desenvolvimento cognitivo e social de alunos com deficiência intelectual, contribuindo para a construção de uma educação mais equitativa e acessível para todos.
DETERMINAÇÃO DA DIFUSIVIDADE MÁSSICA DE LÍQUIDOS EM AR ESTAGNADO ATRAVÉS DA CONSTRUÇÃO DE UMA CÉLULA DE ARNOLD
Authors: Oliveira Samara Lopes Pereira de , Sousa Sabrina Lune Silva Nascimento , Carvalho Júnior Robson de Oliveira , Rodrigues Sthefany Rebouças , Santana Thiago Paim , Azevedo Lenise Cerqueira
Published: November 2024

Este estudo visa determinar o coeficiente de difusão mássica (Dab) de água e etanol utilizando uma célula de Arnold, dispositivo composto por um tubo de PVC com furos onde são introduzidos tubos de ensaio contendo os líquidos a serem analisados. O sistema é montado com suporte universal, termômetro e um filtro de sílica para desumidificação do ar. O experimento foi realizado por 4 horas, com leituras periódicas da variação de altura dos líquidos após a inserção de ar seco com um secador. A água, iniciada Dab com 25 mL, não apresentou variação mensurável, impossibilitando o cálculo do. Já o etanol, que também iniciou com 25 mL, mostrou uma perda de 2 mL nos primeiros 5 minutos e obteve um coeficiente de difusão de aproximadamente 1,0 x 10⁻⁹ m²/s, com desvio teórico de aproximadamente 1,23 x 10⁻⁵%. A partir deste experimento, foi possível verificar a aplicabilidade da célula de Arnold na determinação da difusividade mássica de líquidos em gases, demonstrando ser um dispositivo simples e eficiente.
A RESPONSABILIDADE CIVIL DO MÉDICO NA RELAÇÃO MÉDICO-PACIENTE
Authors: Oliveira Letícia Barbosa , Carvalho Stefhani Gonçalves de
Published: November 2024

A presente pesquisa discute a evolução da responsabilidade médica e as bases do erro médico. Delton Croce e Croce Júnior explicam que, na antiguidade, a responsabilidade era regida por normas casuísticas, sem uma legislação clara. O Código de Hamurabi e o Código de Manu exemplificam isso, mas só no século XIX surgiram regulamentações mais definitivas. O erro médico, segundo Genival Veloso de França, é uma conduta inadequada que causa danos ao paciente, caracterizada por imperícia, imprudência ou negligência. A culpa, de acordo com o Código Civil Brasileiro, é essencial para determinar a responsabilidade. Imperícia refere-se à falta de habilidade técnica, imprudência envolve decisões apressadas e negligência é a falta de cuidado, frequentemente observada em serviços públicos. Sendo assim, a pesquisa enfatiza a importância de distinguir essas formas de erro e a necessidade de os médicos manterem um padrão adequado de cuidados para prevenir danos, conforme as normas éticas e legais existentes.
ATENÇÃO FARMACÊUTICA NA POLIFARMÁCIA EM IDOSOS COM DOENÇAS METABÓLICAS: UMA REVISÃO INTEGRATIVA DA LITERATURA
Authors: Cazuza Izabela Sales , Pinto Thiago Serrão
Published: November 2024

É evidente um aumento expressivo da população idosa em todo o  mundo assim como as Doenças Crônicas Não Transmissíveis como Hipertensão, diabetes, muito comum em idosos. Acompanhado disso a necessidade de uso de medicamentos diversos a chamada polifarmácia. O objetivo deste estudo é sintetizar e analisar criticamente as evidências disponíveis sobre a atenção farmacêutica na polifarmácia em idosos com doenças metabólicas, por meio da análise abrangente da literatura existente. Trata-se de uma Revisão integrativa da literatura delineada por seis importantes etapas. As bases de dados selecionadas para este estudo foram: Medline, Lilacs, Scielo e Pubmed. Para a elaboração do estudo foram considerados artigos publicados em uma linha temporal estabecido entre o ano de 2020 a 2024. Foi feito uma relação nos Descritores em Ciências da Saúde (DeCS) e Medical Subject Headings (MeSH) seguido de elaboração de um sprint de busca obedecendo a estratégia PICo. Para o refinamento dos artigos utilizou-se o o software Rayyan. Este estudo seguiu rigorosamente os critérios de inclusão estabelecidos. Foram incluidos sete (7) artigos nesta pesquisa que abordaram a temática. Foi encontrado evidencias sobre a demanda da polifarmácia em idosos, os principais achados patológicos, com destaque a hipertensão, diabete e dislipidemia, além de maior destaque do publico idoso feminino. Por fim, a polifarmácia merece maior atenção por apresentar impacto na saúde e, dessa forma, necessidade da atenção especializada da atuação do profissional farmacêutico.
A ESTAÇÃO JUNDIAHY PAULISTA – “ESTAÇÃOZINHA”: A CRIAÇÃO DE UM ESPAÇO MULTIUSO PROMOTOR DE CULTURA, EVENTOS E TURISMO PARA A CIDADE DE JUNDIAÍ
Authors: Munarolo Maria Aparecida Souza , Ballerini Adriana Perroni
Published: November 2024

O presente artigo visa mostrar como um patrimônio cultural afetivo, neste caso específico, a Estação Jundiahy Paulista, mais conhecida como “Estaçãozinha”, inaugurada em 1898 com a função de desafogar a Estação São Paulo Railway, a “Inglesa”, pode vir a ser um agente promotor de cultura, eventos e turismo para a cidade de Jundiaí-SP. A metodologia empregada tem caráter qualitativo, pautando-se em pesquisas bibliográficas, eletrônicas, documentais, e empírica a partir da imersão de uma das autoras no universo referido, e depoimentos cedidos pelo Instituto Envelhecer que enriqueceram a compreensão dos aspectos abordados, a fim de: resgatar sua história e importância no cenário da cidade de Jundiaí, tendo-se em vista seu desenvolvimento por meio da ferrovia; analisar o patrimônio “Estaçãozinha” como lugar de memória, ressaltando-se as oportunidades e desafios para sua preservação; relatar as experiências vivenciadas por uma das autoras no contexto de membro fundador do movimento “Estaçãozinha pede socorro”, em que diversas ações sociais foram empreendidas a fim de trazer a este patrimônio afetivo visibilidade; e reconhecer as potencialidades culturais desse local e propor sugestões para sua refuncionalização. Diante disso, faz-se necessário lançar um olhar sobre as políticas de patrimônio em nosso país para que passem a contemplar, ainda mais, tanto o conjunto arquitetônico em si como o significado deste para a sociedade.
PANDEMIA DA COVID 19 E A EDUCAÇÃO NO BRASIL
Authors: Souza Jane Alves de , Silva Viviane Maria da , Sardeiro Filho Almir Tavares , Barbosa Dirce Marivone Janczeski , Silva Nilma Aparecida do Carmo , Santos Ana Lucia Oliveira , Dias Elisângela Menezes , Oliveira Luzinete Coelho de
Published: November 2024

A pandemia de COVID-19 no país forçou inúmeras mudanças importantes em todos os setores que envolvem a sociedade e também influenciou de forma direta a educação, que precisou passar de forma abrupta para uma instrução remota, causando vários impactos de infraestrutura e também emocionais, pois com o ensino remoto foi necessária a utilização de tecnologias que nem todos os educandos tinham acesso afetando diretamente a aprendizagem dos educandos que ficaram defasados em sua aprendizagem e muitos evadiram para ajudar suas famílias. O presente artigo vem fazendo uma análise dos desafios que a educação enfrentou durante esse período que acabou por aprofundar a desigualdades educacionais, principalmente devido ao acesso aos recursos tecnológicos. Além de discutir também os problemas emocionais que essa pandemia trouxe para a vida dos educandos e também dos educadores, compreendendo o que foi feito pelos responsáveis para melhorar os desafios encontrados na educação. Sendo possível compreender e mesmo com as dificuldades, a pandemia também trouxe benefícios através de uma nova forma de enxergar a educação através das tecnologias, buscando a inclusão através das inovações tecnológicas para um futuro melhor.
RECONSTRUCTING CHILD CUSTODY POST-DIVORCE IN ISLAMIC FAMILY LAW: A BEST INTEREST OF THE CHILD-BASED APPROACH IN THE CONTEMPORARY ERA
Authors: Ushalli Muhammad Uswah , Ushalli Eskarni , Hayati Naila , Ushalli Lillahi
Published: November 2024

The concept of child custody post-divorce has been a critical issue in Islamic family law, particularly in light of contemporary debates surrounding children’s rights and welfare. In recent decades, there has been a growing emphasis on the Best Interest of the Child (BIC) standard, which has shaped custody decisions in Western legal systems. This article explores the integration of the BIC principle within Islamic family law, specifically addressing how it can be reconstructed to align with modern child welfare needs. Through a comprehensive literature review, the paper examines Islamic legal sources, including the Qur’an, Hadith, and classical fiqh, to evaluate the traditional understanding of child custody in divorce cases. It further investigates the compatibility of Islamic principles with international human rights frameworks that advocate for the child's best interest. The article highlights the challenges and opportunities in adapting Islamic family law to contemporary child custody norms, considering cultural, legal, and societal factors. It also compares the Islamic approach with Western legal perspectives on child welfare, identifying areas for potential reform. The findings suggest that while Islamic law provides a strong foundation for protecting children's rights, it requires contextual adaptation to ensure the child’s best interests are consistently prioritized. This research calls for a balanced and progressive approach to reforming child custody practices within Islamic family law. Ultimately, it aims to contribute to a more child-centered framework in Islamic legal systems, offering insights for policymakers and legal practitioners.