bluuebunny/crossref_metadata_2025 huggingface dataset:
Óvodapedagógusok a romániai kisgyermeknevelés intézményi változásának sodrásában
Authors:   Babeş-Bolyai University, Cluj Napoca, Barabási Tünde , Stark Gabriella ,   Babeş-Bolyai University, Cluj Napoca
Published: March 2024

In Romania since 2022 the nursery education has been moved from the social area into the educational system, according to 100/2021 Emergency Government Decree. The effects of the changes caused by this regulation in the institutional system are wide-ranging and may affect kindergarten teachers as well. In our paper we are going to the answer on one hand, to what extent the appearance of early childhood education within the framework of educational institutions is known by kindergarten teachers; on the other hand, what kind of reception reactions to the changes brought about by the modification can we outline; and what new alternative career opportunities it reveals for the research sample. Accordingly, the aim of our research is to map the institutional structure variants outlined by the legal regulations, the examination of attitudes towards these changes and exploring the effects on career aspirations of kindergarten teachers. We start from the assumption that the changes in the law reveal alternative career paths for kindergarten teachers, which is more attractive for those with a pragmatist approach. Our second hypothesis is that the movement of early childhood education into the educational segment is ambivalently judged, as opinions are nuanced on the scale of risk association and opportunity recognition. We have used the method of document analysis, and the empirical research is based on a self-made questionnaire. Using an access sampling procedure, we included 213 Hungarian kindergarten teachers from Romania in our study. Through the investigation, we clarify the institutional alternatives of early childhood education in Romania, outline the professional framework of the early childhood education profession, and the possible alternative career paths, as well as their assessment by kindergarten teachers. Our results show that the reception reactions of the mentioned institutional changes are positive among kindergarten teachers, who emphasize also that this structural modification provides the possibility of validation of the early education curriculums integrated approach and practical application.
Image Processing Techniques for Crack Detection in MPI of Springs
Authors: Marciniak Marcin M.
Published: March 2024

This study investigates image processing techniques for detecting surface cracks in spring steel components, with a focus on applications like Magnetic Particle Inspection (MPI) in industries such as railways and automotive. The research details a comprehensive methodology that covers data collection, software tools, and image processing methods. Various techniques, including Canny edge detection, Hough Transform, Gabor Filters, and Convolutional Neural Networks (CNNs), are evaluated for their effectiveness in crack detection. The study identifies the most successful methods, providing valuable insights into their performance. The paper also introduces a novel batch processing approach for efficient and automated crack detection across multiple images. The trade-offs between detection accuracy and processing speed are analyzed for the Morphological Top-hat filter and Canny edge filter methods. The Top-hat method, with thresholding after filtering, excelled in crack detection, with no false positives in tested images. The Canny edge filter, while efficient with adjusted parameters, needs further optimization for reducing false positives. In conclusion, the Top-hat method offers an efficient approach for crack detection during MPI. This research offers a foundation for developing advanced automated crack detection system, not only to spring sector but also extends to various industrial processes such as casting and forging tools and products, thereby widening the scope of applicability.
Medicinal Mushrooms Cordyceps as a New Source of Bioactive Compounds and Their Complexation With Silver Ions
Authors: Uhrinová Anna , Maľučká Lucia Ungvarská
Published: March 2024

Mushrooms from the genus Cordyceps are characterized by a wide range of biological effects due to the diverse amount of substances contained in them and are an important source of bioactive compounds. In China, mushrooms of the genus Cordyceps have been used as a medicinal preparation of traditional Chinese medicine for centuries. So far, a considerable number of studies have been conducted that focused on analyzing the effects of Cordyceps, which include their antioxidant, antibacterial, immunomodulatory, antidiabetic, antitumor, and many other effects. The ability of fungi to form complexes with various metals is also interesting. It is believed that polysaccharides are the main component of the extracts involved in the complexation with metals, after which their biological effects are improved and deepened. The work deals with the comparison of the antioxidant and antibacterial effects of Cordyceps extracts with extracts of this mushroom enriched with silver ions. Based on scientific studies, it is assumed that there is a complexation between the chemical compounds of the extracts and silver.
Aminopeptidase N as a potential drug target
Authors: Farsa Oldřich , Ballayová Veronika , Žáčková Radka , Zubáč Peter
Published: March 2024

Aminopeptidase N (APN) is a broad specificity zinc metallopeptidase with many functions that do not always depend on its enzymatic activity. Among others, it is involved in tumor angiogenesis and metastasizing and also serves as a cellular receptor of some coronaviruses. Some APN inhibitors, such as bestatin or tosedostat, were used or tested as anticancer drugs in the past. Within the past two decades, we have prepared several series of potential APN inhibitors. Some of them reached interesting values of inhibitory activity and were also successfully tested for antiproliferation activity in cancer cell lines. We also performed some QSAR studies with APN inhibitors prepared by us and other authors.
Characteristics of Trust in Personal Financial Planning*
Authors: Cull Michelle , Sloan Terry
Published: March 2024

This Australian study utilises quantitative and qualitative research planning. Affective characteristics of trust were found to be essential to the client-adviser relationship. Increased legislation and specific behavioural and technical competencies of advisers were also found to build consumer trust in financial advice. The study’s results provide guidance to financial advisers with regards to the skills and factors that build and maintain trust with clients. This may lead some advisers to engage in additional training or education programs to improve specific skills, or to reconsider the way they interact with clients.
Can Stakeholders be Satisfied with Accountants’ Education to Act as Advisors to Self-Managed Superannuation Funds
Authors: Freudenberg Brett , Boccabella Dale
Published: March 2024

This article investigates to what extent accountants are taught about self-managed superannuation funds (SMSF) in their Australian undergraduate accounting degrees and subsequent professional education programs. The article reports a survey of 138 academics teaching into Australian undergraduate accounting degrees. The results indicate that during their undergraduate accounting degrees, students are likely to be taught little about SMSFs. In a curriculum audit of their subsequent professional studies through professional bodies there is also minimal coverage of SMSFs. The evidence presented in this paper supports reforms to increase the educational requirements for accountants to give specialist advice in this area.
True Links: Precursory Lessons from Golf for Effective Financial Behaviour
Authors: Knutsen Julie Therese , Malin Mirela , West Tracey , Brimble Mark
Published: March 2024

This article presents the results from a preliminary study which finds there are three psychological errors common to golf and financial behaviour which are the cause of unfavourable outcomes, namely overoptimism, overconfidence and emotional judgements. To manage these errors, this study finds the same strategies used to improve golfing decisions could carry over into our understanding of effective financial behaviour. Further, linking the research of effective golf play with effective financial behaviour leverages upon a worldwide interest which we argue has the potential to provide a range of analogies and visual clues for financial education and financial planning.
Formar professores para os desafios profissionais futuros
Authors: Batista Paula
Published: March 2024

Esta reflexão parte dos desafios que se colocam à formação de professores para explorar o potencial formativo das comunidades de prática e do prático-investigador na arquitetura da formação de professores. O mote são estudos de revisão de literatura, identificados nas bases de dados B-on e Scopus na última década, sobre as comunidades de prática e o prático-investigador na formação de professores, coadjuvados com evidências resultantes de projetos de investigação desenvolvidos no âmbito do 2.º Ciclo em Ensino da Educação Física para os Ensinos Básico e Secundário da Faculdade de Desporto da Universidade do Porto. Foram identificadas vantagens em configurar a formação de professores e o desenvolvimento profissional num continuum, em espaços partilhados, como comunidades de prática/aprendizagem, em que os/as professores/as das escolas e da faculdade cooperam na formação de futuros professores e, simultaneamente, se desenvolvem profissionalmente. As comunidades necessitam de ser descentralizadas e democráticas para serem sustentáveis. A formação de professores baseada na investigação pode servir como força motriz para vincular os/as futuros/as professores/as a práticas informadas pela pesquisa. Já a sua permanência, como práticos-investigadores, reclama por uma cultura de escola que apoie e valorize a investigação educacional.
Formação de professores: Construindo uma agenda para o século XXI
Authors: Swennen Anja , Leite Carlinda , Lopes Amélia
Published: March 2024

Em julho de 2022, o Porto acolheu uma conferência internacional do EDULOG sobre formação de professores sob o tema desafiante: "Formação de Professores: Construir uma Agenda para o Século XXI". O principal motivo que levou à organização desta conferência foi o reconhecimento coletivo, tanto na comunidade internacional como na comunidade educativa, dos profundos desafios que se colocam à educação atual e futura. Foi partilhada a convicção de que a formação de professores é fundamental para o avanço da educação. Os formadores de professores, quer nas instituições de ensino superior quer nas escolas, têm a tarefa de formar todos/as os/as professores/as, influenciando assim indiretamente as práticas de ensino de todos/as os/as educadores/as e as experiências de aprendizagem de todos/as os/as alunos/as. Trata-se de uma tarefa imensa e de grande responsabilidade.
Pengaruh Iklan YouTube terhadap Brand Awareness
Authors: Gavrila Sherina , Sari Wulan Purnama
Published: March 2024

In this day and age, technology and information are increasing, many new games have appeared that are of interest to Generation Z children. One of them is Tower OF Fantasy, an RPG genre game developed by a Chinese company called Hotta Studio. developed and published by Level Infinite. Even if many games have the same or similar genres, developers try to make their games available to the masses. Hotta Studio uses a communication strategy in the form of advertising. Hotta Studio uses YouTube advertising to increase brand awareness. The purpose of this study was to determine the impact of Tower of Fantasy YouTube advertising on brand awareness. This study used a quantitative method through a survey method using a survey as a data collection method. The results of data analysis using a simple linear regression test showed that the coefficient of determination was 0.475, which corresponds to YouTube Tower of Fantasy influence and brand awareness of 47.5%. Also, using a simple linear regression test, we can see that the value of the regression coefficient is 0.482, so it can be translated that for every 1 level of YouTube advertising costs, the value of brand awareness increases. about 0.482., which means that the direction of influence of X and Y is positive. 

Di era sekarang ini teknologi dan informasi kian berkembang banyak bermunculan banyak game baru yang diminati oleh anak-anak gen z. Salah satunya adalah Tower OF Fantasy yang merupakan game bergenre action RPG yang dibuat oleh perusahaan asal China yaitu Hotta Studio dan dipublikasikan oleh Level Infinite. Walaupun banyak game memiliki genre yang sama atau serupa , para developer berusaha untuk memperkenalkan game hasil buatan mereka kepada publik. Hotta Studio menggunakan salah satu strategi komunikasi yaitu berupa iklan. Hotta Studio menggunakan iklan YouTube untuk meningkatkan brand awareness. Penelitian ini bertujuan untuk mengetahui pengaruh yang diberikan oleh iklan YouTube Tower of Fantasy terhadap brand awareness. Penelitian ini menggunakan metode kuantitatif melalui metode kuesioner menggunakan survei sebagai metode pengumpulan data. Hasil dari analisis data melalui uji regresi linear sederhana menunjukan hasil besarnya koefisien determinasi sebesar 0,475 yang menunjukan bahwa pengaruh variabel iklan YouTube Tower of Fantasy dan Brand Awareness adalah sebesar 47,5%. Melalui uji regresi linear sederhana juga dapat dilihat bahwa nilai koefisien regresi sebesar 0,482 maka dapat diterjemahkan untuk setiap kenaikan 1% biaya variabel iklan YouTube, skor kesadaran merek meningkat sebesar 0,482, yang dapat diartikan bahwa arah pengaruh X dan Y adalah positif.
Event Sebagai Pendukung Komunikasi Pemasaran Perusahaan Allo Bank dalam Membangun Kesadaran Merek
Authors: Hardjono Baby Setiawaty , Setyanto Yugih
Published: March 2024

PT. Allo Bank Indonesia Tbk (Allo Bank) is one of the digital banks in Indonesia under the auspices of CT Corpora. The purpose of this study is to explain event activities as a support for marketing communications carried out by Allo Bank in building brand awareness through the Allo Bank Festival 2022 which presents K-Pop groups. This study uses several supporting concepts, namely Communication, Marketing Communication, and Brand Awareness. The author uses qualitative research methods. The subject of this research is an event organizer and currently works in Allo Bank's digital customer service department, K-Pop fans, and also Allo Bank users. While the object of this research is the Allo Bank Festival 2022 event, which is a marketing communication activity used by Allo Bank in building brand awareness. Data from research results were obtained through interviews, observation, documentation, and literature studies. The results of the research show that the Allo Bank Festival 2022 event which presents K-Pop groups has succeeded in attracting audiences in building brand awareness. Marketing communications used by Allo Bank are events and publications which are included in the marketing communications mix, namely public relations.
PT. Allo Bank Indonesia Tbk (Allo Bank) adalah salah satu bank digital di Indonesia yang berada di bawah naungan CT Corpora. Penelitian ini menjelaskan kegiatan event sebagai pendukung komunikasi pemasaran yang dilakukan oleh Allo Bank dalam membangun kesadaran merek lewat Allo Bank Festival 2022 yang menghadirkan grup K-Pop. Penulis menggunakan metode penelitian kualitatif dengan teknik pengumpulan data berupa wawancara panitia, penggemar K-Pop, dan nasabah. Hasil penelitian menunjukkan kegiatan event Allo Bank Festival 2022 yang menghadirkan grup K-Pop berhasil memberi daya tarik pada khalayak dalam membangun kesadaran merek. Komunikasi pemasaran yang digunakan Allo Bank adalah dengan menyelenggarakan event dan publikasi, termasuk dalam bauran komunikasi pemasaran yaitu hubungan masyarakat.
Menggali Potensi TikTok: Pendekatan Pemasaran Digital Produk Kecantikan ‘FAV BEAUTY’
Authors: Hadi Surya Dalvin , Erdiansyah Rezi
Published: March 2024

This research analyzes the role of the TikTok social media platform as a means of marketing communication for the "FAV BEAUTY" product through a qualitative approach with the characteristics of the Integrated Marketing Communication (IMC) theory. In this context, the research aims to explore how TikTok can be effectively integrated into marketing strategies to enhance brand communication and deepen consumer engagement. Qualitative research methods were employed, including in-depth interviews with consumers, content analysis of TikTok related to "FAV BEAUTY," and observations of the marketing campaigns run by the brand. The research findings indicate that TikTok can create more personal and emotional interactions between the brand and consumers by combining visual elements, music, and user creativity. Within the framework of the IMC theory, this research provides a comprehensive understanding of how TikTok can be integrated into a holistic marketing strategy, where marketing messages are coordinated effectively across various communication channels. The implications of these findings not only offer practical insights for "FAV BEAUTY" but also contribute to marketing literature and IMC theory, highlighting the potential of TikTok as a vital communication tool in the context of beauty product marketing.
Penelitian ini menganalisis peran media sosial TikTok sebagai sarana komunikasi pemasaran produk "FAV BEAUTY" melalui pendekatan kualitatif dengan karakteristik teori Integrated Marketing Communication (IMC). Tujuan penelitian untuk menggali bagaimana TikTok dapat diintegrasikan secara efektif dalam strategi pemasaran untuk meningkatkan komunikasi merek dan memperdalam keterlibatan konsumen. Metode penelitian kualitatif digunakan, termasuk wawancara mendalam dengan konsumen, analisis konten TikTok terkait "FAV BEAUTY," dan observasi terhadap kampanye pemasaran yang dijalankan oleh merek tersebut. Temuan penelitian menunjukkan bahwa TikTok mampu menciptakan interaksi yang lebih personal dan emosional antara merek dan konsumen, dengan menggabungkan elemen visual, musik, dan kreativitas pengguna. Dalam kerangka teori IMC, penelitian ini memberikan pemahaman mendalam tentang bagaimana TikTok dapat diintegrasikan dalam strategi pemasaran yang holistik, di mana pesan pemasaran terkoordinasi secara efektif melalui berbagai saluran komunikasi. Implikasi temuan ini tidak hanya memberikan wawasan praktis bagi "FAV BEAUTY" tetapi juga menyumbang pada literatur pemasaran dan teori IMC, menyoroti potensi media sosial TikTok sebagai alat komunikasi yang penting dalam konteks pemasaran produk kecantikan.
A Assessment of stone ash as a lightweight concrete constituent material with the addition of bestmittel additives
Authors: Budiman Budiman , Tiranda Patanduk James Williams
Published: March 2024

Technological advances in the field of building construction have developed very rapidly, so we need a construction technology that can reduce exploitation of nature. Utilization of stone ash is one of the new material alternatives in concrete mixtures with the addition of the bestmittel additive to accelerate drying in concrete. The purpose of this study is to determine the aggregate characteristics, specific gravity and compressive strength of concrete. The method used is laboratory experimental research with variations in stone ash samples of 5%, 10% and 15% to the weight of sand with the addition of 0.6% bestmittell additive to the weight of cement. The results showed that stone ash and bestmittell additives affect the characteristics of the concrete. The value of specific gravity increases with increasing percentage of stone ash, namely 1898.77 kg/m3 in normal concrete, 1911.35 kg/m3 of 5% stone ash concrete, 1922.34 kg/m3 of 10% stone ash concrete and 1927.06 kg/m3 m3 on 10% stone ash concrete. The compressive strength value of characteristic for the compositions AB 5%, AB 10% and AB 15% are 10.08 Mpa, 10.35 Mpa and 10.88 Mpa respectively, an increase compared to normal AB 0% concrete, namely 9.03 Mpa at 28 days.
DETERMINATION OF THE OPTIMAL TRAJECTORY OF THE MOVEMENT OF AIRCRAFT IN AREAS WITH COMPLEX TERRAIN UNDER THE CONTROL OF THE ENEMY
Authors:   Department of Computer systems and programming, National Aviation Academy,  Institute of Information Technology, Baku, Azerbaijan, Aghayev Nadir , Kalbiyev Namig ,   Department of Computer systems and programming, National Aviation Academy, Aghazade Sabina ,   Department of Computer systems and programming, National Aviation Academy
Published: March 2024

One of the main issues in the controlling of aircraft in difficult terrain during wartime is to ensure normal movement, but also to fulfill the requirements of evading enemy control. This paper proposes an improved ant swarm algorithm that makes it possible to pre-determine and optimize the trajectory of aircraft in such areas. When applying this method, a special parameter is included in the probability of choosing a movement trajectory – the height of the terrain above sea level, so that each ant does not enter territory controlled by the enemy. Using a 2D-H digital elevation map, the rectangular area under study is divided into 90 m × 90 m squares. To take into account the variability of the terrain, the heuristic function of the ant swarm algorithm takes into account the parameters of distance, height and smooth surface. Additionally, to reduce the number of iterations and computations, the ants are divided in half by number and released from the start and end points simultaneously. As a result, it allows you to choose the shortest and minimum trajectory among various calculated trajectories. To verify the effectiveness of the proposed scheme, a number of computational experiments were conducted. Experimental results on various simulated and real terrain maps show that this algorithm can be used to select an initial reference trajectory in difficult terrain.
IDENTIFIKASI DAN SEBARAN JENIS Cinnamomum sintoc BL DENGAN MENGGUNAKAN SISTEM INFORMASI GEOGRAFI (SIG) DI RESORT CILIMUS DAN MANDIRANCAN TAMAN NASIONAL GUNUNG CIREMAI
Authors: Ismail Agus Yadi , Kosasih Dede , Novitasari Dian
Published: March 2024

Jenis Cinnamomum sintoc Blume merupakan salah satu vegetasi penghasil minyak atsiri pada batang dan daunnya. Dalam upaya konservasi C.sintoc, maka perlu dilakukan studi untuk mengetahui populasi dan sebaran sintok diTaman Nasional Gunung Ciremai.Penelitian ini dilakukan untuk memperoleh informasi mengenai populasi, sebaran, dan karakteristik habitat  Cinnamomum sintoc di Resort Cilimus dan Resort Mandirancan Taman Nasional Gunung Ciremaisehingga proses kelangkaannya dapat dicegah dan pengembangan dapat dilakukan dalam upaya pembudidayaan tanaman ini. Penelitian dilaksanakan di Resort Cilimus dan Mandirancan Taman Nasional Gunung Ciremai Provinsi Jawa Barat yang terletak pada koordinat 108° 24' 20.3706" - 108° 28' 40.2486" Bujur Timur dan 6° 49' 30.9185"- 6° 54' 3.8434" Lintang Selatan dengan luas wilayah 3.171,035 hektar. Penelitian dimulai bulan Juni sampai dengan bulan Agustus 2016. Identifikasi morfologi dan sebaran C.sintoc menggunakan metode observasi dengan melakukan penelitian langsung ke lapangan yang dilakukan di Resort Cilimus dan Mandirancan dibatasi berdasarkan ketinggian dari 500-1200 mdpl.Hasil penelitian menunjukkan bahwa Sebaran Cinnamomum sintoc pada lokasi penelitian banyak ditemukan individu pada Resort Cilimus sedangkan untuk Resort Mandirancan cenderung mengelompok terutama pada ketinggian 700 mdpal dan 900 mdpal.selain itu Habitat di Resort Cilimus Cinnamomum sintoc ditemukan hanya pada ketinggian 500-1200 mdpal dengan rata-rata suhu 26.3oC dan kelembaban 78% dan Resort Mandirancan ditemukan hanya pada ketinggian 500-1100 mdpal dengan rata-rata suhu 27.3oC dan kelembaban 75.5%. Dan habitat Cinnamomum sintocditemukan pada Zona tropik dataran rendah (0-1000 Mdpal) dan Zona sub montan atau Hutan pegunungan rendah (1000-1500 Mdpal).Kata Kunci: Cinnamomum sintoc, habitat, morfologi, sebaran
KEANEKARAGAMAN MAKROFAUNA TANAH PADA TUTUPAN LAHAN PINUS DAN SEMAK BELUKAR DI STASIUN PENELITIAN KARANGSARI TAMAN NASIONAL GUNUNG CIREMAI
Authors: Purnama Rofi , Adhya Ilham , Supartono Toto
Published: March 2024

This diversity aims to determine the various species of soil macrofauna and the diversity of soil macrofauna in two different land covers in the Karangsari Research Station, Gunung Ciremai National Park (TNGC). This research was carried out at the Karangsari Research Station of Gunung Ciremai National Park (TNCG) in May-June 2022 using the squared method and Hand sorting. Data analysis included population density, relative density, attendance fraction, and Shanon Weiner diversity index. The results showed that in two land covers, 18 orders / families were found with 1034 individuals, 606 individuals were found in bush cover and 428 individuals were found in pine stands dominated by Formicidae. The calculation of the abundance of all soil macrofauna found in pine stands was 158.51 individuals / Ha smaller than the abundance of all types found in seak land cover of 224.44 individuals / Ha with a diversity value of 2.32 or moderately categorized. The 18 orders/families found include Arachnids, Armadillidae, Blatodea, Centipede, Chelicerastes, Coleoptera, Dermaptera, Formicidae, Gastropods, Gryllidae, Hexapods, Isopods, Lumbricidae, Milipede, Polydesmida, Rhinofermitidae, Tetragnathidae, and Tomoceridae.Keanekragaman ini bertujuan untuk mengetahui berbagai spesies macrofauna tanah dan keanekaragaman macrofauna tanah pada dua tutupan lahan berbeda di Stasiun Penelitian Karangsari, Taman Nasional Gunung Ciremai (TNGC). Penelitian ini dilaksanakan di Stasiun Penelitian Karangsari Taman Nasional Gunung Ciremai (TNCG) pada bulan Mei-Juni 2022 dengan menggunakan metode kuadrat dan Hand sorting. Analisis data diantaranya kepadatan populasi, kepadatan relatif, frkuensi kehadiran, dan indeks keanekaragaman Shanon Weiner. Hasil penelitian menunjukan pada dua tutupan lahan ditemukan sebanyak 18 ordo/famili dengan jumlah individu sebanyak 1034 individu, pada tutupan semak ditemukan 606 individu dan pada tegakan pinus ditemukan 428 individu yang didominasi oleh Formicidae. Perhitungan kelimpahan seluruh macrofauna tanah yang ditemukan pada tegakan pinus yaitu sebanyak 158,51 individu/Ha lebih kecil dibandingkan dengan kelimpahan seluruh jenis yang ditemukan pada tutupan lahan seak yaitu sebanyak 224,44 individu/Ha dengan nilai keanekaragaman sebesar 2,32 atau dikategorikan sedang. 18 ordo/famili yang ditemukan diantaranya arachnida, Armadillidae, Blatodea, Centipede, Chelicerastes, Coleoptera, Dermaptera, Formicidae, Gastropoda, Gryllidae, Hexapoda, Isopoda, Lumbricidae, Milipede, Polydesmida, Rhinofermitidae, Tetragnathidae, dan Tomoceridae.
Personal Library: Formation, Structure, Semantics (The Library of E. S. Shurygin, for Example)
Authors:   Laboratory of Bibliology, Novosibirsk, Russian Federation, Yarantsev Vladimir N.
Published: March 2024

In this article, the personal library of E. S. Shurygin, a well-known connoisseur of poetry in Siberia and an engineer by profession, is considered from the point of view of both the composition and structure of the library itself, and the personal qualities and aspirations of its owner. The objective and subjective factors of library formation are analyzed, the main of which is the era of the «sixties» and its representatives, the criteria for its status are identified. It is concluded that the personal library of E. S. Shurygin for the nature of his worldview.
Assessment of the quality of life in patients with onychomycosis and mycosis of the feet with concomitant non-alcoholic fatty liver disease against the background of complex therapy
Authors: Rustamkhanova Gulnaz R. , Hismatullina Zarema R. , Vlasova Natalia A. , Gashimova Dinara T.
Published: March 2024

Background. Сurrently, much attention is paid to the quality of patients, which is a promising direction of life, allowing to put a complete and objective picture of the disease, determine the most stable method of treatment, and evaluate its results.
Aims. To evaluate the effectiveness of complex therapy in patients with onychomycosis and mycosis of the feet with concomitant non-alcoholic severe liver disease (NAFLD) using a modified questionnaire-questionnaire of the combined index of quality of life (QL-Index).
Methods. The combined index of quality of life (QL-Index) was determined in patients with onychomycosis and mycosis of the feet with with concomitant NAFLD before and after complex therapy.
Results. Analysis of the results of assessing the presence of a combined index of quality of life in 117 patients with onychomycosis and foot mycosis with concomitant NAFLD before treatment showed that the presence of onychomycosis and mycosis of the feet in the majority of respondents has a strong impact on the lives of the respondents (69.2%). After the complex treatment, according to the results of the combined questionnaire-questionnaire of the quality of life index, it was revealed that social activity in patients with onychomycosis and foot mycosis with concomitant NAFLD increased, and the psycho-emotional state improved. The quality of life of patients has improved, which significantly increased the effectiveness of this complex treatment.
Conclusion. The high efficacy and safety of complex therapy, which included the use of the systemic antimycotic itraconazole in combination with external antifungal drugs, a hepatoprotector and a prebiotic in patients with onychomycosis and mycosis of the feet with concomitant NAFLD.
Expected Spesolimab Plasma Exposure following Intravenous and Subcutaneous Dosing in Patients with Generalized Pustular Psoriasis
Authors: Hawkes Jason , Guercio Jason , Kurup Sree , Li Xiujiang , Lebwohl Mark
Published: March 2024

Introduction: Generalized pustular psoriasis (GPP) is a chronic, potentially life-threatening inflammatory skin disease characterized by widespread flares of sterile pustules. Spesolimab is a first-in-class anti-interleukin-36 receptor monoclonal antibody approved to treat GPP flares in adults via intravenous (IV) infusion. The aim of this study was to simulate the plasma pharmacokinetics (PK) of IV versus subcutaneous (SC) doses of spesolimab to compare drug exposure profiles and support dosing strategies in patients with GPP.

 Methods: A population PK model was developed using individual-level PK, anti-drug antibody, and covariate data from eighteen studies in which subjects were treated with IV or SC spesolimab.1 The resulting PK model was used to simulate concentration-time profiles following varying doses of IV and SC spesolimab. Peak plasma concentration (Cmax), time to peak plasma concentration (Tmax), and area under the curve (AUC) were summarized for each dose regimen.

Results: Simulated spesolimab exposures demonstrated that the Cmax and AUC of the single dose 900 mg IV infusion consistently exceeded that of various single doses of SC spesolimab tested. A SC dose greater than two-fold higher would be required to attain a Cmax comparable to that of spesolimab 900 mg IV. The difference in exposure between the two administration routes was most pronounced in the first 2 weeks after administration. Slow absorption is expected with SC injection, with Tmax attained at later time points after SC dosing compared to immediately following the 90-minute infusion for IV dosing. Results were the same when simulating a two-dose regimen administered one week apart.

 Conclusions: PK simulations suggest that treatment with IV and SC spesolimab can result in differences in drug exposure in clinical practice. The immediate and high exposure of IV spesolimab compared with the lower exposure of SC spesolimab are supportive of IV dosing with spesolimab in acute GPP flare treatment vs SC dosing.
Utility of anticoagulation, pre-smearing and post-smearing hemolytic techniques on morphological assessment and reproducibility in fluid cytology
Authors: Agrawal Meetu , Lata Priya , Singh Mukul , Lal Mahesh Kumar , Gupta Bhoomika , Shamsunder Saritha , Rani Shilpi , Madan Neha Kawatra , Ahuja Sana , Ranga Sunil
Published: March 2024

Objective:

Knowledge of proper collection, storage, preservation, and processing techniques is critical to ensuring proper handling and analysis of fluid cytology specimens. This study was conducted to determine the effect of anticoagulation, pre-smearing acetic acid treatment technique, and saline rehydration technique on morphological assessment, reproducibility, and reporting in fluid cytology.

Material and Methods:

The study was carried out in the cytopathology laboratory over 2 months (April–May 2022), where 100 effusion samples were analyzed. At least 20–40 mL of fluid was collected in heparinized and non-heparinized containers for each patient. Samples were processed in cytospin and stained with Giemsa and Papanicolaou stains. For 70 hemorrhagic specimens, an extra smear was prepared from the sediment and subjected to the saline rehydration technique as per the Indian Academy of Cytologists (IAC) guidelines. Seventy-three hemorrhagic specimens whose quantity received was more than 35 mL were subjected to the pre-smearing technique. These smears were evaluated for (a) the presence or absence of blue background/any other background staining, (b) cellularity, (c) cell morphology and (d) the presence/absence of microclots.

Results:

Heparinized samples showed no compromise in cellular morphology or cellularity although a blue background was observed in an occasional case. The pre-smearing technique had less background hemorrhage and preserved cell characteristics. The post-smearing saline rehydration technique did not compromise the cellularity but distorted morphology and showed background staining.

Conclusion:

The pre-smearing acetic acid treatment showed better-preserved cellularity and cytomorphology with the absence of background staining when compared to the post-smearing saline rehydration technique.
Knowledge and Risk Assessment of Hepatitis B Infection among Barbers and Beauty Salon Workers in Mwanza, Tanzania
Authors: Kilonzo Semvua , Jaka Hyasinta , Mapunda Sylvanus
Published: March 2024

Background and Objective

Community-acquired hepatitis B virus (HBV) infection is increasing in developing countries. In Tanzania, there is an exponential increase in barbershops and beauty salons, which are potential sites of transmission of HBV. Occupational exposure rates and HBV vaccination rates among salon workers are unknown; their level of knowledge about infection prevention and control (IPC) is also unknown. This study aimed to evaluate the risk of infection and the knowledge of barbers and beauty salon workers about HBV transmission and prevention.

Methods

A cross-sectional study was conducted using a convenience sample of 200 barbers and beauty salon workers from 13 barber shops and 13 beauty salons in the urban district of Mwanza, Tanzania. Data were collected using a self-administered questionnaire, entered into EpiData version 3.1, and analyzed with Stata version 13. Categorical variables were expressed as frequencies, and association levels were compared using Fisher’s exact test.

Results

Fifty-four percent of the study participants were female, and the mean age was 25 (21.0–29.5) years. A total of 126 (63%) participants were aware of the existence of HBV infection, of which only 22% had general good knowledge of HBV transmission and prevention. Both HBV awareness (P < 0.001) and good knowledge of its transmission and prevention (P = 0.03) were positively associated with higher levels of education. Seventy-three (36.5%) participants reported a history of occupational injuries. Merely 27.8% of participants were familiar with the correct methods of decontamination beauty tools, and only 14.3% understood the correct procedures for post-exposure wound care. Vaccination coverage was low with only (2%) of barbers and beauty salon workers having received vaccines.

Conclusion and Implications for Translations

The frequent occupational injuries and inadequate vaccination among barbers and beauty salon workers amplify their risk of HBV infection. They also lack basic knowledge about HBV transmission and prevention, placing the clients they serve at high risk for infection. We recommend that training on HBV Infection Prevention and Control (IPC) should focus on this specific group, and the implementation of these measures should be closely monitored in barbershops and beauty salons. Moreover, this vulnerable group should be considered for a global vaccination program.
Peculiarities of depicting a landscape in a literary text using the example of Francis Scott Fitzgerald's novel “The Great Gatsby”
Authors: Мурадова А.К. , Газимаева Х.А.
Published: March 2024

В настоящей работе рассматриваются особенности изображения пейзажа в художественном тексте на примере романа Фрэнсиса Скотта Фицджеральда «Великий Гэтсби». Данное литературное произведение, созданное в 20-е годы ХХ века, представляет собой уникальный образец, в котором пейзаж играет существенную роль в раскрытии образов персонажей и основной идеи произведения. В рамках исследования нами были проанализированы отрывки романа, где описываются пейзажи, а также процитированы наиболее яркие и выразительные фрагменты. Было выявлено, что описания природы используются автором для передачи настроения героев и подчеркивания различий между ними. Так, для главного героя Джея Гэтсби характерен восторг перед роскошными садами его усадьбы, тогда как Том Бьюкенен демонстрирует пренебрежение к окружающей среде. Проведенный анализ позволил сделать вывод о том, что Фицджеральд мастерски использует пейзажи для создания атмосферы произведения и раскрытия внутреннего мира персонажей посредством их взаимодействия с окружающей средой. Данный прием позволяет считать роман выдающимся образцом художественного описания пейзажа. Для более наглядной демонстрации изложенных выше положений приведем несколько выдержек непосредственно из романа Фицджеральда с дальнейшим их анализом.

This paper examines the features of the depiction of landscape in a literary text using the example of Francis Scott Fitzgerald's novel The Great Gatsby. This literary work, created in the 20s of the twentieth century, is a unique example in which the landscape plays a significant role in revealing the images of the characters and the main idea of the work. As part of the study, we analyzed excerpts from the novel where landscapes are described, and also quoted the most striking and expressive fragments. It was revealed that descriptions of nature are used by the author to convey the mood of the characters and emphasize the differences between them. Thus, the main character Jay Gatsby is characterized by admiration for the luxurious gardens of his estate, while Tom Buchanan demonstrates disdain for the environment. The analysis led to the conclusion that Fitzgerald masterfully uses landscapes to create the atmosphere of the work and reveal the inner world of the characters through their interaction with the environment. This technique allows us to consider the novel an outstanding example of an artistic description of a landscape. To demonstrate the above provisions more clearly, we present several excerpts directly from Fitzgerald’s novel with their further analysis.
Adaptation of methods of distance learning of foreign languages in Russian universities in the era of digitalization
Authors: Мохова О.Л. , Жигалова М.Р. , Миронова Д.А. , Малыхина И.А.
Published: March 2024

В текущей эпохе цифровизации происходит неотвратимая трансформация образовательных парадигм, в частности в сфере иностранных языков. В современной России, примерно 30% вузов активно адаптируют методики дистанционного обучения для обучения иностранным языкам, согласно исследованию, проведенному Российским университетом дружбы народов в 2020 году. В данной статье проводится всесторонний анализ существующих методик и их адаптации к российским образовательным стандартам. Особое внимание уделяется исследованию качественных и количественных показателей эффективности применения дистанционных методик на основе мета-анализа 25 научных статей, индексированных в базах данных Scopus и WoS, а также анализа данных, собранных из 15 российских вузов. На основании данных, предоставленных Министерством науки и высшего образования Российской Федерации, 63% российских вузов начали процесс интеграции методик дистанционного обучения в 2019 году, и этот показатель вырос на 17% в 2021 году. Примечательно, что более 72% курсов иностранных языков в вузах используют смешанные формы обучения, которые включают как очные, так и дистанционные элементы. Подобный подход позволяет оптимизировать процесс обучения, как показало исследование Всероссийского научно-исследовательского института информационных технологий в образовании в 2020 году, где уровень удовлетворенности студентов составил 81%.

In the current era of digitalization, there is an inevitable transformation of educational paradigms, in particular in the field of foreign languages. In modern Russia, approximately 30% of universities actively adapt distance learning methods for teaching foreign languages, according to a study conducted by the Peoples' Friendship University of Russia in 2020. This article provides a comprehensive analysis of existing methods and their adaptation to Russian educational standards. Special attention is paid to the study of qualitative and quantitative indicators of the effectiveness of remote techniques based on meta-analysis of 25 scientific articles indexed in the Scopus and WoS databases, as well as analysis of data collected from 15 Russian universities. Based on data provided by the Ministry of Science and Higher Education of the Russian Federation, 63% of Russian universities began the process of integrating distance learning methods in 2019, and this figure increased by 17% in 2021. It is noteworthy that more than 72% of foreign language courses at universities use mixed forms of education, which include both full-time and distance elements. Such an approach makes it possible to optimize the learning process, as shown by a study by the All-Russian Research Institute of Information Technologies in Education in 2020, where the level of student satisfaction was 81%.
Infrastructure in the field of customs services: categorical and conceptual apparatus’ structural model and analysis
Authors: Lisitsa A. A.
Published: March 2024

The article analyzes scientific approaches to the definition of the terms “infrastructure”, “customs infrastructure”, “infrastructure in the field of customs services”, including in the context of functional aspects.

   The study purpose is to form theoretical approaches and analyze the categorical and conceptual apparatus of the infrastructure in the field of customs as an institution of customs service, the consumers of whose services are the state, society and business.

   The problem urgency is due to the ongoing changes in the external and internal environment of customs administration: the service orientation global vector of public administration.

   The study objective is to form the author’s definition of the concept of service customs infrastructure, reflecting the target function, economic, functional, technical and social characteristics. The study concept is based on the theory of service-oriented customs administration in the field of customs services and on methodological approaches of the scientific school of the Russian Customs Academy. Based on the types’ analysis of customs services, the interests’ system of customs sphere subjects, a systematic approach to the concept under study has been substantiated, and a structural model of infrastructure in the field of customs services, classification of its elements according to vertical and horizontal principles have been developed. The analysis of regulatory and legal documents defining the standard requirements for the objects of production and information technology infrastructure of the automobile checkpoint is carried out. The results obtained allow us to propose the author’s definition of infrastructure in the field of customs services in a narrow and broad sense. Conclusions have beendrawn about the directions of improving the infrastructure in the field of customs services based on a service-oriented approach.
Organizational and legal aspects of ensuring infrastructural interaction between business and higher education
Authors: Kotelevskaya Yu. V.
Published: March 2024

The legal foundations’ study for ensuring infrastructural interaction between business and higher education is the basis for building a hypothesis about the need to improve the conditions for the effective use of scientific developments, the development of intellectual capital and commercialization, as well as for the practical applicability of research achievements. The article analyzes the legislative basis that forms the basis for the interaction of business and higher education, where it is justified that small and medium-sized businesses should act as entrepreneurial activities. The analysis made it possible to identify shortcomings in the legislation that do not consider the requests of all interested parties (stakeholders). The interrelation of national projects is considered and it is highlighted that at the moment there is a trend in legislation to create conditions for interaction between business and higher education. In addition, a number of arguments are given justifying that in order to achieve economic development considering digital transformations of the economy, it is necessary to create conditions for ensuring infrastructural interaction between business and higher education, where small and medium-sized businesses act as entrepreneurship with the active participation of authorities.
Industrial policy in the chemical industry in the context of economic sanctions against Russia
Authors: Frolov D. L.
Published: March 2024

The high importance of the chemical industry for the Russian economy in the socio-economic and foreign trade aspects causes increased attention to this industry. The need to provide all production, household and agricultural areas with products and raw materials supplied from chemical enterprises poses the task of reducing dependence on imports, which has developed over the past decades for most commodity items. The negative effect of import dependence became apparent after the introduction of anti-Russian sanctions back in 2014 and significantly intensified in 2022. These events have accelerated the work towards self-sufficiency in key chemical products. The study highlights the main stages of developing the program measures on import substitution, the evolution of some target indicators values and its implementation degree. The current state of the chemical industry in the country has been showed, its bias towards export-oriented industries assessed (fertilizers, synthetic rubber, ammonia, polymers, tires production). The attention to low-tonnage chemistry has decreased, which led to the deficit of its domestic production and the imports growth. The article studies the state of exports and the balance of trade in the main chemical products produced and consumed in Russia.