bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure Legend from mTOR Inhibitors Block Kaposi Sarcoma Growth by Inhibiting Essential Autocrine Growth Factors and Tumor Angiogenesis
Authors: Roy Debasmita , Sin Sang-Hoon , Lucas Amy , Venkataramanan Raman , Wang Ling , Eason Anthony , Chavakula Veenadhari , Hilton Isaac B. , Tamburro Kristen M. , Damania Blossom , Dittmer Dirk P.
Published: March 2023

PDF file - 73K
Supplementary Figure 3 from MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells
Authors: Wang Wen-Jun , Wu Si-Pei , Liu Jia-Bin , Shi Yong-Sheng , Huang Xue , Zhang Qian-Bing , Yao Kai-Tai
Published: March 2023

PDF file - 1299K,A, Western blot detection of CHK1 and CHK2 in CNE2 cells. B, Western blot detection of c-MYC, CHK1 and CHK2 in PKH26+ NPC cells after treated with c-Myc shRNA
Supplementary Methods from Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model
Authors: Sundstrøm Terje , Daphu Inderjit , Wendelbo Ingvild , Hodneland Erlend , Lundervold Arvid , Immervoll Heike , Skaftnesmo Kai Ove , Babic Michal , Jendelova Pavla , Sykova Eva , Lund-Johansen Morten , Bjerkvig Rolf , Thorsen Frits
Published: March 2023

PDF file - 74K, More details on specific topics from main Materials and Methods, including BRAF mutational status, PPB staining, Scanning electron microscopy, Transmission electron microscopy, Histology and Immunohistochemistry data. Also includes supplementary reference.
Supplementary Figure 3 from Tissue Damage–Associated “Danger Signals” Influence T-cell Responses That Promote the Progression of Preneoplasia to Cancer
Authors: He Ying , Zha Jikun , Wang Yamin , Liu Wenhua , Yang Xuanming , Yu Ping
Published: March 2023

PDF file - 20K, The majority of CD11b+ cells were F4/80+ in the prostate of TRAMP mice
Supplementary Figure 2 from Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model
Authors: Sundstrøm Terje , Daphu Inderjit , Wendelbo Ingvild , Hodneland Erlend , Lundervold Arvid , Immervoll Heike , Skaftnesmo Kai Ove , Babic Michal , Jendelova Pavla , Sykova Eva , Lund-Johansen Morten , Bjerkvig Rolf , Thorsen Frits
Published: March 2023

PDF file - 287K, Automated signal quantification flow chart
Supplementary Methods from MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models
Authors: Tovar Christian , Graves Bradford , Packman Kathryn , Filipovic Zoran , Xia Brian Higgins Mingxuan , Tardell Christine , Garrido Rosario , Lee Edmund , Kolinsky Kenneth , To Kwong-Him , Linn Michael , Podlaski Frank , Wovkulich Peter , Vu Binh , Vassilev Lyubomir T.
Published: March 2023

PDF file - 136K, Includes HTRF, cell growth/viability, apoptosis assays and biacore, crystal structure and animal studies. Also includes supplemental references.
Supplementary Figure and Table Legend from Identification of an Aurora Kinase Inhibitor Specific for the Aurora B Isoform
Authors: Xie Hua , Lee Mee-Hyun , Zhu Feng , Reddy Kanamata , Peng Cong , Li Yan , Lim Do Young , Joon Kim Dong , Li Xiang , Kang Soouk , Li Haitao , Ma Weiya , Lubet Ronald A. , Ding Jian , Bode Ann M. , Dong Zigang
Published: March 2023

PDF file - 81K
Supplementary Table 1 from Notch3 Pathway Alterations in Ovarian Cancer
Authors: Hu Wei , Liu Tao , Ivan Cristina , Sun Yunjie , Huang Jie , Mangala Lingegowda S. , Miyake Takahito , Dalton Heather J. , Pradeep Sunila , Rupaimoole Rajesh , Previs Rebecca A. , Han Hee Dong , Bottsford-Miller Justin , Zand Behrouz , Kang Yu , Pecot Chad V. , Nick Alpa M. , Wu Sherry Y. , Lee Ju-Seog , Sehgal Vasudha , Ram Prahlad , Liu Jinsong , Tucker Susan L. , Lopez-Berestein Gabriel , Baggerly Keith A. , Coleman Robert L. , Sood Anil K.
Published: March 2023

PDF file - 96K, Notch Pathway Alterations in Patients with HGS-OvCa.
Supplementary Table 1 from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: March 2023

PDF file - 93KB, PCR Primers and TaqMan qPCR Probes.
Supplementary Figure 2 from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: March 2023

PDF file - 198KB, Mammary tumor growth and metastasis in Tg(TVA)+RCAS-PyMT and Tg(NCOA1)x Tg(TVA)+RCAS-PyMT mice.
Supplementary Figure 3 from Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy
Authors: Lindner Andreas U. , Concannon Caoimhín G. , Boukes Gerhardt J. , Cannon Mary D. , Llambi Fabien , Ryan Deborah , Boland Karen , Kehoe Joan , McNamara Deborah A. , Murray Frank , Kay Elaine W. , Hector Suzanne , Green Douglas R. , Huber Heinrich J. , Prehn Jochen H.M.
Published: March 2023

PDF file - 52K, Systems modeling can act as a clinical tool to determine therapeutic windows and to assess adjuvant treatments.
Supplementary Table 7 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: March 2023

XLSX file - 15K, Set of most significantly enriched canonical pathways as deterermined by IPA analysis based on the gene list in Supplementary Table 5.
Supplementary Methods from Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer
Authors: Maire Virginie , Némati Fariba , Richardson Marion , Vincent-Salomon Anne , Tesson Bruno , Rigaill Guillem , Gravier Eléonore , Marty-Prouvost Bérengère , De Koning Leanne , Lang Guillaume , Gentien David , Dumont Aurélie , Barillot Emmanuel , Marangoni Elisabetta , Decaudin Didier , Roman-Roman Sergio , Pierré Alain , Cruzalegui Francisco , Depil Stéphane , Tucker Gordon C. , Dubois Thierry
Published: March 2023

PDF file - 122K
Supplementary Figure 1 from Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer
Authors: Maire Virginie , Némati Fariba , Richardson Marion , Vincent-Salomon Anne , Tesson Bruno , Rigaill Guillem , Gravier Eléonore , Marty-Prouvost Bérengère , De Koning Leanne , Lang Guillaume , Gentien David , Dumont Aurélie , Barillot Emmanuel , Marangoni Elisabetta , Decaudin Didier , Roman-Roman Sergio , Pierré Alain , Cruzalegui Francisco , Depil Stéphane , Tucker Gordon C. , Dubois Thierry
Published: March 2023

PDF file - 135K, Expression of PLK2, PLK3 and PLK4 in human breast cancers
Supplementary Figures 1 - 6 from Durable Adoptive Immunotherapy for Leukemia Produced by Manipulation of Multiple Regulatory Pathways of CD8+ T-Cell Tolerance
Authors: Berrien-Elliott Melissa M. , Jackson Stephanie R. , Meyer Jennifer M. , Rouskey Craig J. , Nguyen Thanh-Long M. , Yagita Hideo , Greenberg Philip D. , DiPaolo Richard J. , Teague Ryan M.
Published: March 2023

PDF file - 643K, Supplementary Figure S1. Surface expression of co-stimulatory and co-inhibitory molecules on FBL tumor cells. Supplementary Figure S2. Transferred T cells are deleted via apoptosis. Supplementary Figure S3. Survival of transferred T cells is not sufficient for acquisition of effector function. Supplementary Figure S4. Systemic inflammation and provision of high-dose IL-2 fail to prevent deletion of adoptively transferred CD8+ T cells. Supplementary Figure S5. LAG3 blockade has limited additional impact on survival of transferred T cells. Supplementary Figure S6. LAG3 blockade combines with PD-1/CTLA4 blockade to promote expansion and effector function by transferred T cells.
Supplementary Figure Legend from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: March 2023

PDF file - 80K
Supplementary Figure 6 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: March 2023

PDF file - 3310K, JAM-B Fc binds to JAM-Cpos cells, independently of alpha-4 integrin.
Supplementary Methods, Figure Legend from Tumor Suppressor NF2/Merlin Is a Microtubule Stabilizer
Authors: Smole Zlatko , Thoma Claudio R. , Applegate Kathryn T. , Duda Maria , Gutbrodt Katrin L. , Danuser Gaudenz , Krek Wilhelm
Published: March 2023

PDF file - 153K
Supplementary Figure Legend from Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer
Authors: Khalaileh Abed , Dreazen Avigail , Khatib Areej , Apel Roy , Swisa Avital , Kidess-Bassir Norma , Maitra Anirban , Meyuhas Oded , Dor Yuval , Zamir Gideon
Published: March 2023

PDF file - 66K
Supplementary Figure 3 from Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer
Authors: Khalaileh Abed , Dreazen Avigail , Khatib Areej , Apel Roy , Swisa Avital , Kidess-Bassir Norma , Maitra Anirban , Meyuhas Oded , Dor Yuval , Zamir Gideon
Published: March 2023

PDF file - 39K, Pathologic score of PanIN lesions in Pdx1-Cre; LSL-KRAS G12D mice, wild type (n=4 mice) or heterozygous (n=7) for the phospho-rpS6 mutant.
Supplementary Figure 1 from FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57
Authors: Cuevas Rolando , Korzeniewski Nina , Tolstov Yanis , Hohenfellner Markus , Duensing Stefan
Published: March 2023

PDF file - 478K, CEP57 localizes to the centrosome throughout the cell division cycle.
Supplementary Movie S2 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: March 2023

Supplementary Movie S2 AVI file - 1069K, GFP-labeled MDA-MB-231 cells stably expressing Arkadia C937A were seeded on top of a layer of HUVEC cells, and images were acquired every 5 min using a Plan apochromat 20x 0.8 objective on a Zeiss LSM 780 confocal microscope. The movie was created using Imaris software (Bitplane)
Supplementary Figure S6 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: March 2023

Supplementary Figure S6 PDF File - 35K, Validation of RNA-seq data by qPCR
Supplementary Figure 1 from Earlier Detection of Breast Cancer with Ultrasound Molecular Imaging in a Transgenic Mouse Model
Authors: Bachawal Sunitha V. , Jensen Kristin C. , Lutz Amelie M. , Gambhir Sanjiv S. , Tranquart Francois , Tian Lu , Willmann Jürgen K.
Published: March 2023

PDF file - 1480K, Box Plot summarizing the angiogenesis score obtained for the four different histological stages (normal, hyperplasia, DCIS and invasive) of breast cancer).
Supplementary Table 2 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: March 2023

PDF file - 57K, COX regression multivariate analysis for the predictive factor biochemical recurrence (BCR).
Supplementary Data from BRMS1 Suppresses Lung Cancer Metastases through an E3 Ligase Function on Histone Acetyltransferase p300
Authors: Liu Yuan , Mayo Marty W. , Nagji Alykhan S. , Hall Emily H. , Shock Lisa S. , Xiao Aizhen , Stelow Edward B. , Jones David R.
Published: March 2023

Supplementary Data PDF file - 682K, SD Fig.1 NSCLC H157 cells stably expressed GFP-BRMS1 (BRMS1) or empty vector (Control) were transfected with vector encoding HA-p300 or empty vector (CMV). SD Fig.2 H1299 cells were co-transfected with siRNA BRMS1 or siRNA nontargeting sequences (Left), or HA-BRMS1 or empty vector (CMV, Right), and Flag-tagged p/CAF. The expression of Flag-p/CAF was assessed. SD Fig.3 (A) and (B) None of the lysine residues in the 2042-2157aa region of p300 is responsible for BRMS1-mediated degradation. SD Fig.4 (A) HEK 293T cells were co-transfected with HA-tagged p300 (617-2414) and the indicated HA-tagged BRMS1 or empty vector. SD Fig.5 (A) BRMS1 E3 mutant enhances the invasion potential of NSCLC. The invasion capability of NSCLC H157 and H1299 BRMS1 WT and E3M cells was assessed using invasion assays as described previously (Smith. PW Cancer lett 2009)
Supplementary Figure 1 from β-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
Authors: Mokkapati Sharada , Niopek Katharina , Huang Le , Cunniff Kegan J. , Ruteshouser E. Cristy , deCaestecker Mark , Finegold Milton J. , Huff Vicki
Published: March 2023

PDF file - 1419KB, Characterization of CreERTM-GFP+ cells of fetal liver.
Supplementary Figure 2 from Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15
Authors: Bruzzese Francesca , Hägglöf Christina , Leone Alessandra , Sjöberg Elin , Roca Maria Serena , Kiflemariam Sara , Sjöblom Tobias , Hammarsten Peter , Egevad Lars , Bergh Anders , Östman Arne , Budillon Alfredo , Augsten Martin
Published: March 2023

PDF file - 207KB, GDF15/MIC-1 is expressed by LNCaP prostate cancer cells and NIH-GDF15 fibroblasts.
Supplementary Figure 5 from AMPK Activation by Oncogenesis Is Required to Maintain Cancer Cell Proliferation in Astrocytic Tumors
Authors: Ríos Marcos , Foretz Marc , Viollet Benoit , Prieto Angel , Fraga Máximo , Costoya Jose A. , Señarís Rosa
Published: March 2023

PDF file - 76K, Supplemental Figure 5. Negative controls of pACC immunohistochemistry in human glioblastoma tissue samples.
Supplementary Figure 4 from AMPK Activation by Oncogenesis Is Required to Maintain Cancer Cell Proliferation in Astrocytic Tumors
Authors: Ríos Marcos , Foretz Marc , Viollet Benoit , Prieto Angel , Fraga Máximo , Costoya Jose A. , Señarís Rosa
Published: March 2023

PDF file - 48K, Supplemental figure 4. AMPK inhibition reduces tumour growth ratio in a xenograft model.
Supplementary Table S1 from A Genetic Mouse Model of Invasive Endometrial Cancer Driven by Concurrent Loss of Pten and Lkb1 Is Highly Responsive to mTOR Inhibition
Authors: Cheng Hailing , Liu Pixu , Zhang Fan , Xu Erbo , Symonds Lynn , Ohlson Carolynn E. , Bronson Roderick T. , Maira Sauveur-Michel , Di Tomaso Emmanuelle , Li Jane , Myers Andrea P. , Cantley Lewis C. , Mills Gordon B. , Zhao Jean J.
Published: March 2023

Summary of disease phenotypes.
Supplementary Figure Legend from The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models
Authors: Miyajima Naoto , Tsutsumi Shinji , Sourbier Carole , Beebe Kristin , Mollapour Mehdi , Rivas Candy , Yoshida Soichiro , Trepel Jane B. , Huang Ying , Tatokoro Manabu , Shinohara Nobuo , Nonomura Katsuya , Neckers Len
Published: March 2023

PDF file - 93K
Supplementary Figure 3 from LSECtin Expressed on Melanoma Cells Promotes Tumor Progression by Inhibiting Antitumor T-cell Responses
Authors: Xu Feng , Liu Jing , Liu Di , Liu Biao , Wang Min , Hu Zhiyuan , Du Xuemei , Tang Li , He Fuchu
Published: March 2023

PDF file - 90KB, Supplementary Figure 3 Confirmation of the surface expression of LSECtin on stable B16-mock and B16-LSECtin transfectants by flow cytometry.
Supplementary Figure 8 from Cell Surface Receptor FPR2 Promotes Antitumor Host Defense by Limiting M2 Polarization of Macrophages
Authors: Liu Ying , Chen Keqiang , Wang Chunyan , Gong Wanghua , Yoshimura Teizo , Liu Mingyong , Wang Ji Ming
Published: March 2023

PDF file - 113K, The expression of M1 macrophage markers
Supplementary Figure 5 from An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity
Authors: Williams Kevin J. , Argus Joseph P. , Zhu Yue , Wilks Moses Q. , Marbois Beth N. , York Autumn G. , Kidani Yoko , Pourzia Alexandra L. , Akhavan David , Lisiero Dominique N. , Komisopoulou Evangelia , Henkin Amy H. , Soto Horacio , Chamberlain Brian T. , Vergnes Laurent , Jung Michael E. , Torres Jorge Z. , Liau Linda M. , Christofk Heather R. , Prins Robert M. , Mischel Paul S. , Reue Karen , Graeber Thomas G. , Bensinger Steven J.
Published: March 2023

PDF File - 90K, Loss of SREBP signaling results in the uncoupling of saturated fatty acid biosynthesis from desaturase activity.
Supplementary Figure 3 from Cell Surface Receptor FPR2 Promotes Antitumor Host Defense by Limiting M2 Polarization of Macrophages
Authors: Liu Ying , Chen Keqiang , Wang Chunyan , Gong Wanghua , Yoshimura Teizo , Liu Mingyong , Wang Ji Ming
Published: March 2023

PDF file - 93K, The expression of CCR4 by bone marrow cells
Supplementary Figure 1 from An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity
Authors: Williams Kevin J. , Argus Joseph P. , Zhu Yue , Wilks Moses Q. , Marbois Beth N. , York Autumn G. , Kidani Yoko , Pourzia Alexandra L. , Akhavan David , Lisiero Dominique N. , Komisopoulou Evangelia , Henkin Amy H. , Soto Horacio , Chamberlain Brian T. , Vergnes Laurent , Jung Michael E. , Torres Jorge Z. , Liau Linda M. , Christofk Heather R. , Prins Robert M. , Mischel Paul S. , Reue Karen , Graeber Thomas G. , Bensinger Steven J.
Published: March 2023

PDF File - 158K, Inhibition of lipogenic transcriptional program in various cancer cells.
Supplementary Figure 1 from Cell Surface Receptor FPR2 Promotes Antitumor Host Defense by Limiting M2 Polarization of Macrophages
Authors: Liu Ying , Chen Keqiang , Wang Chunyan , Gong Wanghua , Yoshimura Teizo , Liu Mingyong , Wang Ji Ming
Published: March 2023

PDF file - 155K, Mouse macrophage chemotaxis induced by classical chemoattractants
Supplementary Figure 4 from Chemotherapy Acts as an Adjuvant to Convert the Tumor Microenvironment into a Highly Permissive State for Vaccination-Induced Antitumor Immunity
Authors: Kang Tae Heung , Mao Chih-Ping , Lee Sung Yong , Chen Alexander , Lee Ji-Hyun , Kim Tae Woo , Alvarez Ronald D. , Roden Richard B.S. , Pardoll Drew , Hung Chien-Fu , Wu T.-C.
Published: March 2023

PDF file - 1120K, Effect of chemotherapy on the phenotype of tumor-associated macrophages (TAMs)
Supplementary Figure 3 from Chemotherapy Acts as an Adjuvant to Convert the Tumor Microenvironment into a Highly Permissive State for Vaccination-Induced Antitumor Immunity
Authors: Kang Tae Heung , Mao Chih-Ping , Lee Sung Yong , Chen Alexander , Lee Ji-Hyun , Kim Tae Woo , Alvarez Ronald D. , Roden Richard B.S. , Pardoll Drew , Hung Chien-Fu , Wu T.-C.
Published: March 2023

PDF file - 2370K, Effect of chemotherapy on the frequency of CD11b+ Gr-1+ myeloid-derived suppressor cells (MDSCs)
Supplementary Figure Legends 1-7 from Bcl3 Selectively Promotes Metastasis of ERBB2-Driven Mammary Tumors
Authors: Wakefield Alison , Soukupova Jitka , Montagne Amelie , Ranger Jill , French Rhiannon , Muller William J. , Clarkson Richard W. E.
Published: March 2023

PDF file - 72K, Full description of experimental procedures and results for supplementary figures
Supplementary Figure 1 from Bcl3 Selectively Promotes Metastasis of ERBB2-Driven Mammary Tumors
Authors: Wakefield Alison , Soukupova Jitka , Montagne Amelie , Ranger Jill , French Rhiannon , Muller William J. , Clarkson Richard W. E.
Published: March 2023

PDF file - 118K, Bcl3 expression is elevated in ErbB2 overexpressing human breast cancer cell lines
Supplementary Figure Legends from Predictive Performance of Microarray Gene Signatures: Impact of Tumor Heterogeneity and Multiple Mechanisms of Drug Resistance
Authors: Ng Charlotte K.Y. , Weigelt Britta , A'Hern Roger , Bidard Francois-Clement , Lemetre Christophe , Swanton Charles , Shen Ronglai , Reis-Filho Jorge S.
Published: March 2023

PDF file - 60K
Supplementary Tables 1 - 4 from miR-483-5p Promotes Invasion and Metastasis of Lung Adenocarcinoma by Targeting RhoGDI1 and ALCAM
Authors: Song Qiancheng , Xu Yuanfei , Yang Cuilan , Chen Zhenguo , Jia Chunhong , Chen Juan , Zhang Yue , Lai Pinglin , Fan Xiaorong , Zhou Xuan , Lin Jun , Li Ming , Ma Wenli , Luo Shenqiu , Bai Xiaochun
Published: March 2023

PDF file - 204KB, Supplementary Table 1. Clinicopathologic characteristics of lung adenocarcinoma patients. Supplementary Table 2. Correlation between the clinicopathological features and expression of miR-483-5p. Supplementary Table 3. Correlation between the tumor grades and the expression of proteins. Supplementary Table 4. Oligonucleotides used in this study.
Supplementary Figure 1 from Genetic and Pharmacologic Inhibition of mTORC1 Promotes EMT by a TGF-β–Independent Mechanism
Authors: Mikaelian Ivan , Malek Mouhannad , Gadet Rudy , Viallet Jean , Garcia Amandine , Girard-Gagnepain Anaïs , Hesling Cédric , Gillet Germain , Gonzalo Philippe , Rimokh Ruth , Billaud Marc
Published: March 2023

PDF file - 441K, Supplementary Figure 1: SiRNA screening procedure.
Supplementary Figure 6 from ΔNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis
Authors: Bid Hemant K. , Roberts Ryan D. , Cam Maren , Audino Anthony , Kurmasheva Raushan T. , Lin Jiayuh , Houghton Peter J. , Cam Hakan
Published: March 2023

PDF file - 40K, Verification of IL-6 and IL-8 knockdown efficiency in SKNDZ and OS-17 cell lines.
Supplementary Figure 4 from Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer
Authors: Feigin Michael E. , Akshinthala S. Dipikaa , Araki Kiyomi , Rosenberg Avi Z. , Muthuswamy Lakshmi B. , Martin Bernard , Lehmann Brian D. , Berman Hal K. , Pietenpol Jennifer A. , Cardiff Robert D. , Muthuswamy Senthil K.
Published: March 2023

PDF file - 103K, Mislocalization of SCRIB enhances EGF-induced AKT activation.
Supplementary Methods from Activation of HIF2α in Kidney Proximal Tubule Cells Causes Abnormal Glycogen Deposition but not Tumorigenesis
Authors: Fu Leiping , Wang Gang , Shevchuk Maria M. , Nanus David M. , Gudas Lorraine J.
Published: March 2023

PDF file - 75K, GGT-HIF2αM3 transcript quantification
Supplementary Methods from FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma
Authors: Santo Evan E. , Stroeken Peter , Sluis Peter V. , Koster Jan , Versteeg Rogier , Westerhout Ellen M.
Published: March 2023

Supplementary Methods PDF file - 114K, Includes Lentiviral constructs, Western blotting & Cell fractionation, Luciferase constructs & reporter assay, Cell Viability Assay, Microarray profiling, and TFBS enrichment analysis. Also includes Supplementary References
Supplementary Figure 2 from Pirfenidone Inhibits Pancreatic Cancer Desmoplasia by Regulating Stellate Cells
Authors: Kozono Shingo , Ohuchida Kenoki , Eguchi Daiki , Ikenaga Naoki , Fujiwara Kenji , Cui Lin , Mizumoto Kazuhiro , Tanaka Masao
Published: March 2023

PDF file - 211K, Supplementary Figure 2: Representative photographs showing histological evaluation of Sirius red positive area on subcutaneous pancreatic cancer mouse models.
Supplementary Figure 6 from Trask Loss Enhances Tumorigenic Growth by Liberating Integrin Signaling and Growth Factor Receptor Cross-Talk in Unanchored Cells
Authors: Spassov Danislav S. , Wong Ching Hang , Wong Sunny Y. , Reiter Jeremy F. , Moasser Mark M.
Published: March 2023

PDF file - 428K, Wound healing in Trask+/+ and Trask-/- mice
Supplementary Methods, Figure Legends, and Tables 1 - 5 from Downregulation of the Novel Tumor Suppressor DIRAS1 Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma
Authors: Zhu Ying-Hui , Fu Li , Chen Leilei , Qin Yan-Ru , Liu Haibo , Xie Fajun , Zeng Tingting , Dong Sui-Sui , Li Jiangchao , Li Yan , Dai Yongdong , Xie Dan , Guan Xin-Yuan
Published: March 2023

PDF file - 142K
Supplementary Figure Legend from A Circadian Clock Transcription Model for the Personalization of Cancer Chronotherapy
Authors: Li Xiao-Mei , Mohammad-Djafari Ali , Dumitru Mircea , Dulong Sandrine , Filipski Elisabeth , Siffroi-Fernandez Sandrine , Mteyrek Ali , Scaglione Francesco , Guettier Catherine , Delaunay Franck , Lévi Francis
Published: March 2023

PDF file - 110K
Supplementary Figure Legend from High-Throughput Tyrosine Kinase Activity Profiling Identifies FAK as a Candidate Therapeutic Target in Ewing Sarcoma
Authors: Crompton Brian D. , Carlton Anne L. , Thorner Aaron R. , Christie Amanda L. , Du Jinyan , Calicchio Monica L. , Rivera Miguel N. , Fleming Mark D. , Kohl Nancy E. , Kung Andrew L. , Stegmaier Kimberly
Published: March 2023

PDF file - 17K
Supplementary Figure Legend from Inhibition of Protein Kinase CK2 Reduces Cyp24a1 Expression and Enhances 1,25-Dihydroxyvitamin D3 Antitumor Activity in Human Prostate Cancer Cells
Authors: Luo Wei , Yu Wei-Dong , Ma Yingyu , Chernov Mikhail , Trump Donald L. , Johnson Candace S.
Published: March 2023

PDF file - 69K
Supplementary Figures 1 - 2 from G Protein–Coupled Receptor Kinase GRK5 Phosphorylates Moesin and Regulates Metastasis in Prostate Cancer
Authors: Chakraborty Prabir Kumar , Zhang Yushan , Coomes Alexandra S. , Kim Wan-Ju , Stupay Rachel , Lynch Lauren D. , Atkinson Tamieka , Kim Jae I. , Nie Zhongzhen , Daaka Yehia
Published: March 2023

PDF file - 31K, Figure S1. GRK5 phosphorylates non-GPCR substrates. Figure S2. Moesin regulates migration and invasion of PCa cells.
Supplementary Figure 5 from De Novo Design of a Tumor-Penetrating Peptide
Authors: Alberici Luca , Roth Lise , Sugahara Kazuki N. , Agemy Lilach , Kotamraju Venkata R. , Teesalu Tambet , Bordignon Claudio , Traversari Catia , Rizzardi Gian-Paolo , Ruoslahti Erkki
Published: March 2023

PDF file - 590K, iNGR penetrates into extravascular tumor tissue
Supplementary Figure 2 from De Novo Design of a Tumor-Penetrating Peptide
Authors: Alberici Luca , Roth Lise , Sugahara Kazuki N. , Agemy Lilach , Kotamraju Venkata R. , Teesalu Tambet , Bordignon Claudio , Traversari Catia , Rizzardi Gian-Paolo , Ruoslahti Erkki
Published: March 2023

PDF file - 404K, iNGR does not bind to CD13+ monocytes
Supplementary Figure 1 from De Novo Design of a Tumor-Penetrating Peptide
Authors: Alberici Luca , Roth Lise , Sugahara Kazuki N. , Agemy Lilach , Kotamraju Venkata R. , Teesalu Tambet , Bordignon Claudio , Traversari Catia , Rizzardi Gian-Paolo , Ruoslahti Erkki
Published: March 2023

PDF file - 166K, HUVECs express NGR and CendR motif receptors
Supplementary Figure 5 from MyoD Is a Tumor Suppressor Gene in Medulloblastoma
Authors: Dey Joyoti , Dubuc Adrian M. , Pedro Kyle D. , Thirstrup Derek , Mecham Brig , Northcott Paul A. , Wu Xiaochong , Shih David , Tapscott Stephen J. , LeBlanc Michael , Taylor Michael D. , Olson James M.
Published: March 2023

PDF file - 4148K, Loss of MyoD does not influence its canonical targets in the myogenic differentiation program.
Supplementary Figure 1 from MyoD Is a Tumor Suppressor Gene in Medulloblastoma
Authors: Dey Joyoti , Dubuc Adrian M. , Pedro Kyle D. , Thirstrup Derek , Mecham Brig , Northcott Paul A. , Wu Xiaochong , Shih David , Tapscott Stephen J. , LeBlanc Michael , Taylor Michael D. , Olson James M.
Published: March 2023

PDF file - 25456K, Comparative analysis of MyoD +/+; SmoA2, MyoD +/-; SmoA2 and MyoD-/-; SmoA2 mice.
Supplementary Figure 6 from Combined Anti-CD40 and Anti–IL-23 Monoclonal Antibody Therapy Effectively Suppresses Tumor Growth and Metastases
Authors: von Scheidt Bianca , Leung Patrick S.K. , Yong Michelle C.R. , Zhang Yu , Towne Jennifer E. , Smyth Mark J. , Teng Michele W.L.
Published: March 2023

PDF file - 65K, Specific detection of intracellular IL-23 in LPS stimulated GM-CSF derived BMDCs.
Data Supplement from Neutralizing Murine TGFβR2 Promotes a Differentiated Tumor Cell Phenotype and Inhibits Pancreatic Cancer Metastasis
Authors: Ostapoff Katherine T. , Cenik Bercin Kutluk , Wang Miao , Ye Risheng , Xu Xiaohong , Nugent Desiree , Hagopian Moriah M. , Topalovski Mary , Rivera Lee B. , Carroll Kyla D. , Brekken Rolf A.
Published: March 2023

Supplemental Figures S1-S12. 2G8 does not bind to human TGFβR2 (S1); 2G8 treated stromal cells do not induce tumor cell proliferation (S2); 2G8 inhibits smad2 dependent signaling in a dose dependent fashion (S3); Tgfβr2 inhibition induces apoptosis and inhibits proliferation in a murine transgenic model of PDAC (S4); Tgfβr2 inhibition reduces perfusion and permeability in KIC tumors (S5); Collagen deposition and fibroblast infiltration is reduced after Tgfβr2 inhibition in PDAC (S6); 2G8 preserves M1 macrophage phenotype in the presence of exogenous TGF-β (S7); 2G8 promotes a proinflammatory immune cell phenotype in an immunocompetent model of PDAC (S8); 2G8 reduces metastatic burden in KIC mice (S9); 2G8 inhibition of tumor cell Tgfβr2 alone is insufficient to alter tumor cell epithelial/mesenchymal phenotype in vitro (S10); 2G8 inhibits EMT in multiple in vivo human xenograft models (S11); Cytokine changes in stromal cells in vitro after inhibition of Tgfβr2 (S12).
Supplementary Figure 1 from Mechanisms of Resistance to Intermittent Androgen Deprivation in Patients with Prostate Cancer Identified by a Novel Computational Method
Authors: Morken Jason D. , Packer Aaron , Everett Rebecca A. , Nagy John D. , Kuang Yang
Published: March 2023

PDF file - 78KB, Figure S1. Proliferation-rate plots. (A)-(F) show the proliferation rates (days-1) for patients 2-7, respectively. X-axis is time in days.
Supplementary Movie 1 from Interactions between MUC1 and p120 Catenin Regulate Dynamic Features of Cell Adhesion, Motility, and Metastasis
Authors: Liu Xiang , Yi Chunhui , Wen Yunfei , Radhakrishnan Prakash , Tremayne Jarrod R. , Dao Thongtan , Johnson Keith R. , Hollingsworth Michael A.
Published: March 2023

MOV file - 2670K, Motility S2-013.Neo
Supplemental Methods from Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia
Authors: Fiskus Warren , Saba Nakhle , Shen Min , Ghias Mondana , Liu Jinyun , Gupta Soumyasri Das , Chauhan Lata , Rao Rekha , Gunewardena Sumedha , Schorno Kevin , Austin Christopher P. , Maddocks Kami , Byrd John , Melnick Ari , Huang Peng , Wiestner Adrian , Bhalla Kapil N.
Published: March 2023

Supplemental Methods
Data Supplement from ADAM9 Promotes Lung Cancer Metastases to Brain by a Plasminogen Activator-Based Pathway
Authors: Lin Chen-Yuan , Chen Hung-Jen , Huang Cheng-Chung , Lai Liang-Chuan , Lu Tzu-Pin , Tseng Guan-Chin , Kuo Ting-Ting , Kuok Qian-Yu , Hsu Jennifer L. , Sung Shian-Ying , Hung Mien-Chie , Sher Yuh-Pyng
Published: March 2023

Supplementary Figure S2. Analysis of cell surface integrin β1 expression.
Supplementary Figures 1 - 11 from Identification of Immune Factors Regulating Antitumor Immunity Using Polymeric Vaccines with Multiple Adjuvants
Authors: Ali Omar A. , Verbeke Catia , Johnson Chris , Sands R. Warren , Lewin Sarah A. , White Des , Doherty Edward , Dranoff Glenn , Mooney David J.
Published: March 2023

PDF file - 129KB, Activated dendritic cell numbers at the vaccine implant site (S1); The kinetics of activated dendritic cell generation at vaccine site (S2); IFN-a production at vaccine sites (S3); TNF-a production at vaccine sites (S4); Prophylactic B16-F10 vaccination in MyD88 and TRIF KO models (S5); Vaccine induced T cell recruitment (S6); Comparison of IL-12 production at vaccine sites in wild type and cytotoxic T cell knockout mice (S7); Comparison of IFN-y production at vaccine sites in wild type and cytotoxic T cell knockout mice (S8); Comparison of dendritic cell generation at vaccine sites in wild type and CD8 dendritic cell knockout mice (S9); Comparison of IL-6 production at the vaccine site in wild type and CD8 dendritic cell knockouts (S10); Comparison of G-CSF production at the vaccine site in wild type and CD8 dendritic cell knockout mice (S11).
Supplementary Figures 1 - 8 from FGFR1–WNT–TGF-β Signaling in Prostate Cancer Mouse Models Recapitulates Human Reactive Stroma
Authors: Carstens Julienne L. , Shahi Payam , Van Tsang Susan , Smith Billie , Creighton Chad J. , Zhang Yiqun , Seamans Amber , Seethammagari Mamatha , Vedula Indira , Levitt Jonathan M. , Ittmann Michael M. , Rowley David R. , Spencer David M.
Published: March 2023

PDF file - 1959K, Figure S1. Schematic diagram representing the function of the transgenic systems. Figure S2. Analysis of inducible LRP5 transgene expression. Figure S3. Pathological Matrix. Figure S4. Murine Reactive Stroma Hallmarks. Figure S5. CID-Dependent Seminal Vesicle Occlusion. Figure S6. Immunohistochemical Characterization of FGFR1 Epithelia - WNT Stroma Lesions. Figure S7. LCM qPCR Validation. Figure S8. Distinctive Wnt signature in human reactive stroma grade 3.
Supplementary Figures 1 - 5 from Immune Escape and Survival Mechanisms in Circulating Tumor Cells of Colorectal Cancer
Authors: Steinert Gunnar , Schölch Sebastian , Niemietz Thomas , Iwata Naoki , García Sebastián A. , Behrens Bianca , Voigt Anita , Kloor Matthias , Benner Axel , Bork Ulrich , Rahbari Nuh N. , Büchler Markus W. , Stoecklein Nikolas H. , Weitz Jürgen , Koch Moritz
Published: March 2023

PDF file - 360KB, aCGH analysis of chromosomal aberrations in single CRC-derived CTC and corresponding tumor tissue (S1); An alternative aCGH algorithm confirms the tumor cell identity of the examined single CTC (S2); Validation of the reproducibility of low cell number real-time PCR (S3); Establishment and performance of single cell realtime PCR analysis (S4); Picture of a cluster of 3 CTC from patient HD-2095 (S5).
Supplementary Figure Legends from Activated ERBB2/HER2 Licenses Sensitivity to Apoptosis upon Endoplasmic Reticulum Stress through a PERK-Dependent Pathway
Authors: Martín-Pérez Rosa , Palacios Carmen , Yerbes Rosario , Cano-González Ana , Iglesias-Serret Daniel , Gil Joan , Reginato Mauricio J. , López-Rivas Abelardo
Published: March 2023

PDF file - 39KB
Supplementary Figures 1 - 4 from Cell Fate Factor DACH1 Represses YB-1–Mediated Oncogenic Transcription and Translation
Authors: Wu Kongming , Chen Ke , Wang Chenguang , Jiao Xuanmao , Wang Liping , Zhou Jie , Wang Jing , Li Zhiping , Addya Sankar , Sorensen Poul H. , Lisanti Michael P. , Quong Andrew , Ertel Adam , Pestell Richard G.
Published: March 2023

PDF file - 791K, DACH1 associates with endogenous YB-1 (S1); Phosphorylation determines DACH1 nuclear-cytoplasmic translocation (S2); DACH1 phosphorylation sites govern nuclear translocation of YB-1 (S3); High YB-1 and low DACH1 expression correlates with poor outcome (S4).
Supplementary Figure 3 from p16INK4a Impairs Homologous Recombination–Mediated DNA Repair in Human Papillomavirus–Positive Head and Neck Tumors
Authors: Dok Rüveyda , Kalev Peter , Van Limbergen Evert Jan , Asbagh Layka Abbasi , Vázquez Iria , Hauben Esther , Sablina Anna , Nuyts Sandra
Published: March 2023

PDF file - 44KB, Correlation levels between p16/INK4A and Cyclin D1 expression.
Supplementary Figure 1 from Histone Chaperone CHAF1A Inhibits Differentiation and Promotes Aggressive Neuroblastoma
Authors: Barbieri Eveline , De Preter Katleen , Capasso Mario , Chen Zaowen , Hsu Danielle M. , Tonini Gian Paolo , Lefever Steve , Hicks John , Versteeg Rogier , Pession Andrea , Speleman Frank , Kim Eugene S. , Shohet Jason M.
Published: March 2023

PDF file - 77K, CHAF1A expression correlates with stage of disease.
Data Supplement from Cancer Affects microRNA Expression, Release, and Function in Cardiac and Skeletal Muscle
Authors: Chen Daohong , Goswami Chirayu P. , Burnett Riesa M. , Anjanappa Manjushree , Bhat-Nakshatri Poornima , Muller William , Nakshatri Harikrishna
Published: March 2023

Supplementary Table S1. miRNA array data.
Supplementary Figures S1-S6 from Strict Requirement for Vector-Induced Type I Interferon in Efficacious Antitumor Responses to Virally Encoded IL12
Authors: Melero Ignacio , Quetglas Jose I. , Reboredo Mercedes , Dubrot Juan , Rodriguez-Madoz Juan R. , Mancheño Uxua , Casales Erkuden , Riezu-Boj Jose I. , Ruiz-Guillen Marta , Ochoa Maria C. , Sanmamed Miguel F. , Thieblemont Nathalie , Smerdou Cristian , Hervas-Stubbs Sandra
Published: March 2023

Supplementary Figures S1-S6. The IFN-I response innduced by SSFV-IL-12 is not affeccted by the IL-12 transgene but is impaired in the absence of IFN-I signaling (S1); IFN-I receptor function is critical for the therapeutic effect of SFV-IL-12 (S2); IFN-I receptor function on the hematopoietic cell compartment is critical for the therapeutic effect of SFV-IL-12 (S3); Gating strategy used to identify TAMs and the different MDSC and DC subsets in the tumor microenvironment (S4); The endogenous IFN-I system lies beneath the effects of SFV-IL-12 on the infiltrates of myeloid cells in the tumor microenvironment (S5); The immune gene expression signature in tumors provoked by SFV-IL-12 is largely dependent on the endogenous IFN-I system (S6).
Supplementary Figure 7 from Increased Dietary Vitamin D Suppresses MAPK Signaling, Colitis, and Colon Cancer
Authors: Meeker Stacey , Seamons Audrey , Paik Jisun , Treuting Piper M. , Brabb Thea , Grady William M. , Maggio-Price Lillian
Published: March 2023

PDF file - 149K, AIN93Null diet does not alter expression of proinflammatory and chemotactic cytokines in proximal colon tissue 1 week post H. bilis-infection.
Supplementary Figure 2 from shRNA Kinome Screen Identifies TBK1 as a Therapeutic Target for HER2+ Breast Cancer
Authors: Deng Tao , Liu Jeff C. , Chung Philip E.D. , Uehling David , Aman Ahmed , Joseph Babu , Ketela Troy , Jiang Zhe , Schachter Nathan F. , Rottapel Robert , Egan Sean E. , Al-awar Rima , Moffat Jason , Zacksenhaus Eldad
Published: March 2023

PDF file - 67KB, Supplementary Figure S2 shows results from the primary and validation screens with hits on sphere only or both sphere and monolayer, as well as sensitivity of HC11 cells.
Supplementary Table S1 from LIMD2 Is a Small LIM-Only Protein Overexpressed in Metastatic Lesions That Regulates Cell Motility and Tumor Progression by Directly Binding to and Activating the Integrin-Linked Kinase
Authors: Peng Hongzhuang , Talebzadeh-Farrooji Mehdi , Osborne Michael J. , Prokop Jeremy W. , McDonald Paul C. , Karar Jayashree , Hou Zhaoyuan , He Mei , Kebebew Electron , Orntoft Torben , Herlyn Meenhard , Caton Andrew J. , Fredericks William , Malkowicz Bruce , Paterno Christopher S. , Carolin Alexandra S. , Speicher David W. , Skordalakes Emmanuel , Huang Qihong , Dedhar Shoukat , Borden Katherine L.B. , Rauscher Frank J.
Published: March 2023

Data collection and refinement statistics for the LIMD2 protein.
Data Supplement from TLR7 Promotes Tumor Progression, Chemotherapy Resistance, and Poor Clinical Outcomes in Non–Small Cell Lung Cancer
Authors: Chatterjee Saradiya , Crozet Lucile , Damotte Diane , Iribarren Kristina , Schramm Catherine , Alifano Marco , Lupo Audrey , Cherfils-Vicini Julien , Goc Jeremy , Katsahian Sandrine , Younes Mohammad , Dieu-Nosjean Marie Caroline , Fridman Wolf Herman , Sautès-Fridman Catherine , Cremer Isabelle
Published: March 2023

Supplemental Figures 1-10. Supplementary figure 1 shows that TLR7 antagonist IRS661 specifically blocks TLR7 expression by human A549 cells Supplementary figure 2 shows that TLR7 agonist induces chemoresistance in murine LL/2 cells Supplementary figure 3 shows the pro-tumoral effect of TLR7 stimulation with increasing doses of chemotherapy Supplementary figure 4 shows that Stimulation of TLR7 favors tumor growth and chemoresistance of murine LL/2 cells while TLR7 blockade with an antagonist inhibits tumor growth Supplementary figure 5 shows that TLR7 stimulation induces myeloid cell recruitment into LL/2 tumors in immunocompetent C57BL/6 mice Supplementary figure 6 shows Determining the optimal cutoff for the cohort of patients not treated with neo-adjuvant chemotherapy Supplementary figure 7 shows Determining the optimal cutoff for the cohort of patients treated with neo-adjuvant chemotherapy Supplementary figure 8 shows that non-responders patients to neo-adjuvant chemotherapy have a poor prognosis Supplementary figure 9 shows the correlation graph for TLR7 expression by tumor cells in metastatic lymph nodes and in primary lung tumor, after treatment with neo-adjuvant chemotherapy Supplementary figure 10 shows that High TLR7 expression on tumor cells is associated with low response to neo-adjuvant chemotherapy
Data Supplement from BMP4 Inhibits Breast Cancer Metastasis by Blocking Myeloid-Derived Suppressor Cell Activity
Authors: Cao Yuan , Slaney Clare Y. , Bidwell Bradley N. , Parker Belinda S. , Johnstone Cameron N. , Rautela Jai , Eckhardt Bedrich L. , Anderson Robin L.
Published: March 2023

Supplementary Methods and figure Legends
Data Supplement from BMP4 Inhibits Breast Cancer Metastasis by Blocking Myeloid-Derived Suppressor Cell Activity
Authors: Cao Yuan , Slaney Clare Y. , Bidwell Bradley N. , Parker Belinda S. , Johnstone Cameron N. , Rautela Jai , Eckhardt Bedrich L. , Anderson Robin L.
Published: March 2023

Supplementary Table 1. Genes altered by BMP4 in whole tumor samples.
Data Supplement from BMP4 Inhibits Breast Cancer Metastasis by Blocking Myeloid-Derived Suppressor Cell Activity
Authors: Cao Yuan , Slaney Clare Y. , Bidwell Bradley N. , Parker Belinda S. , Johnstone Cameron N. , Rautela Jai , Eckhardt Bedrich L. , Anderson Robin L.
Published: March 2023

Supplementary Table 2. Gene ontology analysis of clusters (P < 0.05) up-regulated by BMP4 in primary tumors.
Supplementary Figure S3 from LIMD2 Is a Small LIM-Only Protein Overexpressed in Metastatic Lesions That Regulates Cell Motility and Tumor Progression by Directly Binding to and Activating the Integrin-Linked Kinase
Authors: Peng Hongzhuang , Talebzadeh-Farrooji Mehdi , Osborne Michael J. , Prokop Jeremy W. , McDonald Paul C. , Karar Jayashree , Hou Zhaoyuan , He Mei , Kebebew Electron , Orntoft Torben , Herlyn Meenhard , Caton Andrew J. , Fredericks William , Malkowicz Bruce , Paterno Christopher S. , Carolin Alexandra S. , Speicher David W. , Skordalakes Emmanuel , Huang Qihong , Dedhar Shoukat , Borden Katherine L.B. , Rauscher Frank J.
Published: March 2023

Restoration of LIMD2 in siRNA knockdown cells gained the function and phenotype of parental cells.
Data Supplement from BMP4 Inhibits Breast Cancer Metastasis by Blocking Myeloid-Derived Suppressor Cell Activity
Authors: Cao Yuan , Slaney Clare Y. , Bidwell Bradley N. , Parker Belinda S. , Johnstone Cameron N. , Rautela Jai , Eckhardt Bedrich L. , Anderson Robin L.
Published: March 2023

Supplementary Figure 4. Differential suppression of CD4+ and CD8+ T cell activation by granulocytic and monocytic MDSC isolated from 4T1.2 or 4T1.2-BMP4 tumor bearing mice
Supplementary Figure Legends from Apoptosis Imaging for Monitoring DR5 Antibody Accumulation and Pharmacodynamics in Brain Tumors Noninvasively
Authors: Weber Thomas G. , Osl Franz , Renner Anja , Pöschinger Thomas , Galbán Stefanie , Rehemtulla Alnawaz , Scheuer Werner
Published: March 2023

PDF file - 68KB
Supplementary Figure 1 from Apoptosis Imaging for Monitoring DR5 Antibody Accumulation and Pharmacodynamics in Brain Tumors Noninvasively
Authors: Weber Thomas G. , Osl Franz , Renner Anja , Pöschinger Thomas , Galbán Stefanie , Rehemtulla Alnawaz , Scheuer Werner
Published: March 2023

PDF file - 75KB, Supplementary Figure 1 - Highly sensitive apoptosis imaging allows tumor detection and randomization at early time points.
Supplemental Figure 2 from MYCN-Dependent Expression of Sulfatase-2 Regulates Neuroblastoma Cell Survival
Authors: Solari Valeria , Borriello Lucia , Turcatel Gianluca , Shimada Hiroyuki , Sposto Richard , Fernandez G. Esteban , Asgharzadeh Shahab , Yates Edwin A. , Turnbull Jeremy E. , DeClerck Yves A.
Published: March 2023

Negative control for figure 2.
Supplemental Figure 1 from MYCN-Dependent Expression of Sulfatase-2 Regulates Neuroblastoma Cell Survival
Authors: Solari Valeria , Borriello Lucia , Turcatel Gianluca , Shimada Hiroyuki , Sposto Richard , Fernandez G. Esteban , Asgharzadeh Shahab , Yates Edwin A. , Turnbull Jeremy E. , DeClerck Yves A.
Published: March 2023

Analysis of enzyme expression in other non -neuroblastoma cell lines.
Supplementary Methods, Figures 1 - 7, and Tables 1 - 2 from Molecular Rules Governing De Novo Methylation in Cancer
Authors: Nejman Deborah , Straussman Ravid , Steinfeld Israel , Ruvolo Michael , Roberts Douglas , Yakhini Zohar , Cedar Howard
Published: March 2023

PDF file - 10686KB, Supplementary Figure S1. Single molecule methylation analysis. Supplementary Figure S2. Methylation of CRC islands in normal tissues. Supplementary Figure S3. Hypermethylation in cancer Supplementary Figure S4. Coefficient of methylation Supplementary Figure S5. Relationship between histone modifications and DNA methylation in cancer Supplementary Figure S6. Tissue specific DNA methylation in cancer. Supplementary Figure S7. Methylation and expression. Supplementary Table S1. DNA samples analyzed by mDIP arrays Supplementary Table S2. Tumor samples analyzed.
Supplementary Methods from p53 and NF-κB Coregulate Proinflammatory Gene Responses in Human Macrophages
Authors: Lowe Julie M. , Menendez Daniel , Bushel Pierre R. , Shatz Maria , Kirk Erin L. , Troester Melissa A. , Garantziotis Stavros , Fessler Michael B. , Resnick Michael A.
Published: March 2023

PDF file - 30K
Supplementary Figure 5 from Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1
Authors: Bronisz Agnieszka , Wang Yan , Nowicki Michal O. , Peruzzi Pierpaolo , Ansari Khairul I. , Ogawa Daisuke , Balaj Leonora , De Rienzo Gianluca , Mineo Marco , Nakano Ichiro , Ostrowski Michael C. , Hochberg Fred , Weissleder Ralph , Lawler Sean E. , Chiocca E. Antonio , Godlewski Jakub
Published: March 2023

PDF file - 133K, FIGURE S5 related to FIGURE 6. Effect of miR-1 on GBM-derived EVs protein cargo.
Data Supplement from AR-Regulated TWEAK-FN14 Pathway Promotes Prostate Cancer Bone Metastasis
Authors: Yin JuanJuan , Liu Yen-Nien , Tillman Heather , Barrett Ben , Hewitt Stephen , Ylaya Kris , Fang Lei , Lake Ross , Corey Eva , Morrissey Colm , Vessella Robert , Kelly Kathleen
Published: March 2023

Supplemental Table 1. PCR primers. Supplemental Table 2. IHC conditions for TMA samples. Supplemental Table 3. Primary antibodies used in western blot analysis.
Supplementary Materials and Methods, Figures 1 - 4, Table 1 from Tumor-Infiltrating Myeloid Cells Activate Dll4/Notch/TGF-β Signaling to Drive Malignant Progression
Authors: Ohnuki Hidetaka , Jiang Kan , Wang Dunrui , Salvucci Ombretta , Kwak Hyeongil , Sánchez-Martín David , Maric Dragan , Tosato Giovanna
Published: March 2023

PDF file - 1522KB, Supplementary Figure S1: shows the kinetics of EL4, LLC1 and B16F10 tumor growth in WT and Gfi1-KO mice. Supplemental Figure S2: analysis of EL4 and LLC1 tumor vascularization (A); distribution and typical profiles of CD11b+Ly6C+Ly6G- and CD11b+Ly6C+Ly6G+ in spleen and bone marrow of naive and tumor-bearing mice (B-F). Supplementary Figure S3: typical sorting profiles of LLC1 tumorinfiltrating cell populations (A); expression profiles of Notch ligands and receptors in tumor cells and tumor-infiltrating populations (B); cartoon representation of interacting Notch ligands and receptors. Supplementary Figure S4: kinetic analysis of tumor growth with or without DAPT. Supplementary Table 1: Extensive gene expression profiling by qPCR.