bluuebunny/crossref_metadata_2025 huggingface dataset:
Kidney segmentation in neck-to-knee body MRI of 40,000 UK Biobank participants
Authors: Langner Taro , Östling Andreas , Maldonis Lukas , Karlsson Albin , Olmo Daniel , Lindgren Dag , Wallin Andreas , Lundin Lowe , Strand Robin , Ahlström Håkan , Kullberg Joel
Published: December 2020

The UK Biobank is collecting extensive data on health-related characteristics of over half a million volunteers. The biological samples of blood and urine can provide valuable insight on kidney function, with important links to cardiovascular and metabolic health. Further information on kidney anatomy could be obtained by medical imaging. In contrast to the brain, heart, liver, and pancreas, no dedicated Magnetic Resonance Imaging (MRI) is planned for the kidneys. An image-based assessment is nonetheless feasible in the neck-to-knee body MRI intended for abdominal body composition analysis, which also covers the kidneys. In this work, a pipeline for automated segmentation of parenchymal kidney volume in UK Biobank neck-to-knee body MRI is proposed. The underlying neural network reaches a relative error of 3.8%, with Dice score 0.956 in validation on 64 subjects, close to the 2.6% and Dice score 0.962 for repeated segmentation by one human operator. The released MRI of about 40,000 subjects can be processed within one day, yielding volume measurements of left and right kidney. Algorithmic quality ratings enabled the exclusion of outliers and potential failure cases. The resulting measurements can be studied and shared for large-scale investigation of associations and longitudinal changes in parenchymal kidney volume.
Feasibility of a transmucosal sublingual fentanyl tablet as a procedural pain treatment in colonoscopy patients: a prospective placebo-controlled randomized study
Authors: Fihlman Mari , Karru E. , Varpe P. , Huhtinen H. , Hagelberg N. , Saari T. I. , Olkkola K. T.
Published: December 2020

Since patients often experience pain and unpleasantness during a colonoscopy, the present study aimed to evaluate the efficacy and safety of sublingually administered fentanyl tablets for pain treatment. Furthermore, since the use of intravenous drugs significantly increases colonoscopy costs, sublingual tablets could be a cost-effective alternative to intravenous sedation. We conducted a prospective placebo-controlled randomized study of 158 patients to evaluate the analgesic effect of a 100 µg dose of sublingual fentanyl administered before a colonoscopy. Pain, sedation, nausea, and satisfaction were assessed during the colonoscopy by the patients as well as the endoscopists and nurses. Respiratory rate and peripheral arteriolar oxygen saturation were monitored throughout the procedure. There were no differences between the fentanyl and placebo groups in any of the measured variables. The median pain intensity values, as measured using a numerical rating scale, were 4.5 in the fentanyl group and 5 in the placebo group. The sedation and oxygen saturation levels and the respiratory rate did not differ between the groups. The majority of the colonoscopies were completed.Our results indicate that a 100 µg dose of sublingual fentanyl is not beneficial compared to the placebo in the treatment of procedural pain during a colonoscopy.
A class III WRKY transcription factor in sugarcane was involved in biotic and abiotic stress responses
Authors: Wang Dongjiao , Wang Ling , Su Weihua , Ren Yongjuan , You Chuihuai , Zhang Chang , Que Youxiong , Su Yachun
Published: December 2020

WRKY transcription factors play significant roles in plant stress responses. In this study, a class III WRKY gene ScWRKY5, was successfully isolated from sugarcane variety ROC22. The ScWRKY5 was a nucleus protein with transcriptional activation activity. The ScWRKY5 gene was constitutively expressed in all the sugarcane tissues, with the highest expression level in the stem epidermis and the lowest in the root. After inoculation with Sporisorium scitamineum for 1 d, the expression level of ScWRKY5 was significantly increased in two smut-resistant varieties (YZ01-1413 and LC05-136), while it was decreased in three smut-susceptible varieties (ROC22, YZ03-103, and FN40). Besides, the expression level of ScWRKY5 was increased by the plant hormones salicylic acid (SA) and abscisic acid (ABA), as well as the abiotic factors polyethylene glycol (PEG) and sodium chloride (NaCl). Transient overexpression of the ScWRKY5 gene enhanced the resistance of Nicotiana benthamiana to the tobacco bacterial pathogen Ralstonia solanacearum, however the transiently overexpressed N. benthamiana was more sensitive to the tobacco fungal pathogen Fusarium solani var. coeruleum. These results provide a reference for further research on the resistance function of sugarcane WRKY genes.
CMR-derived ECVs vary with myocardial region
and associate with the regional wall thickness
Authors: Su Mao-Yuan , Hou Kuei-Yuan , Liu Ming-Hung , Lin Tien-Min , Juang Jyh-Ming Jimmy , Lin Lian-Yu , Wu Cho-Kai , Yu Hsi-Yu , Yang Shun-Chung , Huang Yu-Sen , Niisato Emi , Chang Yeun-Chung
Published: December 2020

This study was designed to identify whether the position and size of the
region of interest (ROI) influence extracellular volume fraction (ECV) measurements.
Patients with localized (n = 203) or infiltrative (n = 215) cardiomyopathies and 36
normal controls were enrolled in this study. ECV measurements at 4 different regions,
including the anterior, septal, posterior and lateral wall regions, were measured, and
all groups were compared. Regional ECV was correlated with the corresponding regional
wall thickness. The diagnostic power to differentiate the myocardial abnormalities was
evaluated for each myocardial region. ECVs measured using five different ROI sizes
within each myocardial region were compared. Our results showed that ECVs varied among
the myocardial regions, and this variation was significantly associated with regional
wall thicknesses. For the detection of myocardial abnormalities, regional ECV revealed
similar results as ECV derived from the whole region except for the anterior region. No
significant difference was found in the ECVs measured using the five different ROI
sizes. In conclusion, CMR-derived ECVs vary with myocardial region, and this variation
is significantly associated with the regional wall thickness. In contrast, the measured
size of the ROI has less of an effect on the ECV.
Transfer learning with chest X-rays for ER patient classification
Authors: Stubblefield Jonathan , Hervert Mitchell , Causey Jason L. , Qualls Jake A. , Dong Wei , Cai Lingrui , Fowler Jennifer , Bellis Emily , Walker Karl , Moore Jason H. , Nehring Sara , Huang Xiuzhen
Published: December 2020

One of the challenges with urgent evaluation of patients with acute respiratory distress syndrome (ARDS) in the emergency room (ER) is distinguishing between cardiac vs infectious etiologies for their pulmonary findings. We conducted a retrospective study with the collected data of 171 ER patients. ER patient classification for cardiac and infection causes was evaluated with clinical data and chest X-ray image data. We show that a deep-learning model trained with an external image data set can be used to extract image features and improve the classification accuracy of a data set that does not contain enough image data to train a deep-learning model. An analysis of clinical feature importance was performed to identify the most important clinical features for ER patient classification. The current model is publicly available with an interface at the web link: http://nbttranslationalresearch.org/.
External beam radiotherapy with or without californium-252 neutron brachytherapy for treatment of recurrence after definitive chemoradiotherapy
Authors: Wu Wen-an , Yang Yi-ping , Liang Jing , Zhao Jin , Wang Jian-sheng , Zhang Jia
Published: December 2020

We aimed to evaluate the application of external beam radiotherapy (EBRT) combined with californium-252 (252Cf) neutron intraluminal brachytherapy (NBT) in patients with local recurrent esophageal cancer after definitive chemoradiotherapy (CRT). Sixty-two patients with local recurrent esophageal squamous cell carcinoma after definitive CRT were retrospectively analyzed; 31 patients underwent NBT+EBRT, and 31 received EBRT alone. The response rate; 1-, 2-, and 3-year overall survival rates; and adverse event occurrence rates were compared between these two patient groups. The response rate was 83.87% (26/31) in the NBT+EBRT group and 67.74% (21/31) in the EBRT group (p < 0.001). The 1-, 2-, and 3-year overall survival rates were 80.6%, 32.3%, and 6.5%, respectively, in the EBRT group, with a median survival time of 18 months. The 1-, 2-, and 3-year overall survival rates were 83.8%, 41.9%, and 6.9%, respectively, in the NBT+EBRT group, with a median survival time of 19 months. The differences between the groups were not significant (p = 0.352). Regarding acute toxicity, no incidences of fistula or massive bleeding were observed during the treatment period. The incidences of severe and late complications were not significantly different between the two groups (p = 0.080). However, the causes of death for all patients differed between the groups. Our data indicate that 252Cf-NBT+EBRT produces favorable local control for patients with local recurrent esophageal cancer after CRT, with tolerable side effects.
Development of a new approach to diagnosis of the early fluorosis forms by means of FTIR and Raman microspectroscopy
Authors: Seredin Pavel , Goloshchapov Dmitry , Ippolitov Yuri , Vongsvivut Jitraporn
Published: December 2020

This study is aimed at investigating the features of mineralization of the enamel apatite at initial stages of fluorosis development. Samples of teeth with intact and fluorotic enamel in an early stage of the disease development (Thylstrup–Fejerskov Index = 1–3) were studied by Raman scattering and FTIR using Infrared Microspectroscopy beamline at Australian Synchrotron equipment. Based on the data obtained by optical microspectroscopy and calculation of the coefficient R [A-type/B-type], which represents the ratio of carbonation fraction of CO32−, replacing phosphate or hydroxyl radicals in the enamel apatite lattice, the features of mineralization of enamel apatite in the initial stages of development of the pathology caused by an increased content of fluorine in the oral cavity were established. Statistical analysis of the data showed significant differences in the mean values of R [A-type/B-type] ratio between the control and experimental groups for surface layers (p < 0.01). The data obtained are potentially significant as benchmarks in the development of a new approach to preventive diagnostics of the development of initial and clinically unregistered stages of human teeth fluorosis, as well as personalized control of the use of fluoride-containing caries-preventive agents.
Synthesis and antibacterial activity of modified ε-polylysine
Authors: Cai Qunshan , Zhu Hongwei , Zhong Keli
Published: December 2020

In this paper, Ugi reaction was used to synthesize the modified polylysine (M-ε-PL) in two steps, and OD value was measured by ultraviolet spectrophotometer to determine the inhibitory rate of M-ε-PL in different concentrations of Escherichia coli and Staphylococcus aureus. The results showed that the antibacterial effect was better with the increase of concentration of M-ε-PL. Among them, 20 mg/mL M-εPL had better bacteriostatic effect on E. coli and S. aureus. The antibacterial rate was 70% and 44%.
Study on optimum synthesis of ethyl cyanoacetate
Authors: Chen Hong , Zhu Bao-wei , Liang Hai , Yang He , Wang Hao-yi
Published: December 2020

Ethyl cyanoacetate is an important chemical intermediate and has been used widely. Ethyl cyanoacetate was prepared by esterification of cyanoacetic acid and absolute ethanol with mixed catalyst (the same proportion of silicotungstic and p-toluene sulfonic acid as catalyst). The influence factors of the amount of catalyst, n(cyanoacetic acid): n ( absolute ethanol), reaction time and reaction temperature on the esterification rate was investigated by orthogonal experiment of four factors and three levels. The product was analyzed by gas chromatography to determine the optimum reaction conditions.
Synthesis and Structure of the Copper Complex [CuL(4, 4′bipy)(H2O)2](H2O)(ClO4)
Authors: Wang Zhaodong
Published: December 2020

The reaction of N-(pyridine-2-ylmethyl)pyrazine-2-carboxamide (HL), 4, 4′-bipyridine(4, 4′-bipy) and copper(II) perchlorate leads to the formation of a new copper complex, [CuL(4, 4′bipy)(H2O)2](H2O)(ClO4) (1), The X-ray crystal analysis reveals that it is a mononuclear complex. CCDC: 1487818, 1.
The Synthesis of Mesoporous TS-1 and Its Performance for Oxidation of Diphenyl Sulfide and Dibenzyl Sulfide
Authors: Wang Hua-Qin , Ding Ya-Long , Yu Pei , Li Ya-Meng , Gao Hai-Xiang , Sun Wen-Jie , Chen Meng-Die , Li RongQiang
Published: December 2020

TS-1 zeolite has outstanding performance in the catalytic reactions with hydrogen peroxide as catalytic promoter. However, the narrow pore size (< 1.0 nm) of traditional TS-1 makes it difficult for bulky organic compounds to contact with the active sites in the pores, which seriously limits application of TS-1. Recently, the introduction of mesoporous structure into microporous TS-1 becomes a hot research topic. Meanwhile, the huge synthesis cost of TS-1 is another main reason hindering its industrial application. In this paper, mesoporous TS-1 was successfully synthesized using sodium silicate as silicon source and titanium trichloride as titanium source under the template conditions of tetrapropylammonium hydroxide (TPAOH) and cationic polymer. The mesoporous TS-1 was characterized by X-ray diffraction (XRD), N2 adsorption, scanning electric microscopy (SEM), transmitting electric microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR) and UV-Vis Spectrum spectra (UV-Vis). Results show that the synthesized TS-1 zeolites have good crystallinity and tetra-coordinated framework Ti atoms, and there are abundant mesoporous structures in the zeolite crystals. The results of oxidation experiments show that conversion of diphenyl sulfide and dibenzyl sulfide with mesoporous TS-1 are 97.3 % and 85.3 % respectively, while that conversion with microporous TS-1 are 75.7 % and 63.5 respectively.
Analysis of Indoor Natural Gas Leakage Explosion
Authors: Sun Liwen , Li Guangpeng
Published: December 2020

The safety accident of indoor natural gas supply system is the process of natural gas leakage and diffusion, most of which are turbulent processes affected by many factors. When the natural gas leaks into the indoor confined space, it will mix with the air to form a mixture. When the oxygen in the natural gas and the air reaches a certain concentration range, combustion or explosion will occur when it meets the ignition source. This paper mainly introduces the influencing factors and calculation methods of the explosion limit of natural gas, and analyzes the calculation methods of the explosion limit of multi-component combustible mixed gas.
Research on Flexible Reliability Evaluation of Distribution Network System with Distributed Energy Access
Authors: Gu Zhihong , Wen Wei , Liu Zhuo
Published: December 2020

Access to distributed energy has brought a greater impact on the system. By analyzing the flexibility of the distribution network itself, considering the evaluation indicators of the three dimensions of effect, degree and service, this paper designs a flexible reliability evaluation index system for the distribution network, using principal component analysis and multi-level fuzzy comprehensive evaluation thoughts, a flexible reliability model was established, and calculation examples were analyzed, which is helpful to provide guidance for the development of regional distribution networks.
Research on Quantitative Evaluation Model of Investment Value of Power Grid Enterprises’ New Business Based on Real Options
Authors: Wang Yongli , Xu Nan , Wang Xiaohui , Zhou Minhan , Wang Lei
Published: December 2020

With the continuous advancement of the power system reform, especially after the introduction of equipment capital to participate in the competition, the business development of power grid companies is facing increasingly severe internal and external tests. While continuing to do a good job in regulated businesses centered on transmission and distribution business, vigorously develop new businesses and strive to achieve high-quality development in a complex market environment. Through the evaluation of the intrinsic value of new businesses of power grid companies, investors can clarify the true value of new businesses, better identify and avoid potential risks, and encourage investors to invest rationally. This article first expounds the types of new businesses of power grid companies, introduces the basic overview of real option theory, and constructs a value evaluation model of discounted cash flow model plus real option theory pricing model, and through case analysis, the feasibility of empirical option theory in the evaluation of new business of power grid investment value is verified.
Selection and Application of Materials in Chemical Machinery Design
Authors: Xiao Ziyi , Du Zhongfa , Huang Zhejun , Tang Anyang
Published: December 2020

Materials used in the design of chemical machinery are an indispensable part of industrial production, and chemical machinery materials are also the main basis of chemical production.Chemical mechanical properties can directly determine the quality of products in chemical production, and their materials also determine the quality of chemical mechanical properties. Selecting corresponding materials has become the core of chemical mechanical design.Therefore, in the design of chemical machinery, there is a special value for the selection of materials used in manufacturing.
A new model for calculating the critical fluid carrying rate in inclined Wells
Authors: Huang Quan Hua , Lin Xing Yu
Published: December 2020

In the preparation of gas production plan and the study of gas well proration we often judge the fluid carrying capacity of gas well by the critical fluid carrying rate of the gas well, and then adjust the production plan. At present, spherical droplet model and ellipsoidal droplet model are often used to calculate the fluid flow in gas Wells, but the spherical cap droplet model has not been concerned by relevant scholars. Therefore, we studied the application range of spherical cap droplet model, established relevant mechanical expressions, and finally obtained the formula for calculating the minimum critical liquid carrying rate of spherical cap droplet model. The results show that the spherical cap droplet model cannot be ignored in the conventional droplet model and has a wide range of applications. At the same time, the model is validated by combining with gas Wells of H gas reservoir, and the model has good applicability.
The influence of different cutting parameters on the glass edge quality
Authors: Li Xiaoyu , Jiang Liangbao , Wang Minbo , Liu Jiaxi , Li Jiaming , Yan Yue
Published: December 2020

The influence of different cutting parameters on the glass edge quality was investigated, including the cutter material, the sharpening angle of the cutting roll, the cutting speed and the load applied to the roll. The results show that there are less defects on the edge of the glass cut by diamond cutter. There is no obvious influence of cutting speed on the glass edge quality. The cutter with a smaller sharpening angle is more applicable for the cutting of thin glass, and the thick glass is more suitable to use a bigger sharpening angle cutter. Higher cutting load is helpful for the breaking of the glass along the cutting line. However, it may cause more defects on the edge and the surface of the glass.
Thermal analysis of electric vehicle DC charging pile power module based on two-dimensional ordered porous structure radiator
Authors: Han Ying , Liu Zhi-jun , Hou Chun-guang , Cao Yun-dong , Zhai Li-rong
Published: December 2020

In order to improve the heat dissipation performance and study the factors affecting the heat dissipation effect of a two-dimensional ordered porous structure, a thermal analysis of the radiator in the power module of a DC charging pile was carried out. Based on the thermal analysis of the grid-type radiator, the square-hole radiator is subjected to a thermal analysis, the heat dissipation performance of the two radiators is compared, and the factors affecting the heat dissipation effect of the square-hole radiator are explored. Research shows that the heat dissipation effect of the square-hole radiator, which represents a twodimensional ordered porous structure, is better than that of the grid-type radiator. The factors affecting the heat dissipation effect of the square-hole radiator are mainly related to the height of the radiator and are positively related to the heat dissipation effect of the radiator.
Research on the Construction Method of Intelligent Prediction and Analysis Model for the Whole Process of Power Grid Project Cost
Authors: Liang Zuobin , Gao Shan , Wang Qing , Dai Yong , Rong Peng , Ye Jun , Gao Yunxing
Published: December 2020

The government’s supervision of power grid enterprises will gradually focus on the transmission and distribution price, and the investment and income will be more strictly supervised. Under the new management requirements, the company must pay more attention to the compliance of the investment process, further strengthen the investment risk control, put an end to inefficient or invalid investment, strengthen the all-round and whole process supervision, and scientifically and accurately determine and carry out effective project cost control and management. It is the key to achieve project management objectives, and also an important measure of investment fine management and control. This paper takes historical cost data as the research object, constructs the whole process intelligent prediction and analysis model of power grid project cost, assists investment decision-making, reduces the balance rate, and improves the efficiency and efficiency of the company’s investment and lean management level.
Performance of a new desiccant bed using phase change material
Authors: Zallama Boutheina , Ghedira Leila Zili , Ben Nasrallah Sassi
Published: December 2020

The main objective of this study was to conduct an experimental analysis to investigate the performance of a new desiccant bed. Therefore, tests were carried out in a desiccator filled with a porous media, i.e. silica gel used as desiccant enhanced with phase change material, using variable inlet climate conditions. Experimental tests were performed to assess the effect of the new packed bed on the adsorption capacity and this by evaluating the outlet evolutions of temperature, relative humidity and absolute humidity. The experimental setup used in this study is a blower enabling to adjust the flow rate, temperature and relative humidity. The amount of adsorbed mass of moisture is also measured and discussed.
Coupled Effect of temperature and additions on the rheological behavior of concrete equivalent mortars (CEM)
Authors: Dada El Hadja , Belaidi Akram Salah-Eddine , Soualhi Hamza , Kadri El Hadj
Published: December 2020

The aim of this work is to study the influence of mineral additions on the rheological behavior of low impact environmental concrete with its concrete equivalent mortar (CEM) at different temperatures.The experimental study is carried out on cement-based CEM substituted by two additions namely, natural pozzolana (PZ) and marble powder (PM), with a substitution rate of 5 to 20%, a ratio of water on binder E / L = 0.5 and a percentage of superplasticizer based on polycarboxylates SP = 0.30%. The rheological parameters, the workability and the flow time of the mixtures were tested by a coaxial rheometer, a mini cone and the LCPC maniabilitimetre respectively at 10 ° C, 20 ° C and 30 ° C. The results show that the substitution of cement by natural pozzolana and marble powder in binary system generally improved viscosity and yield stress at 20°C and 30°C, while at 10°C natural pozzolana negatively affected the rheological parameters and workability.
Numerical Simulation of Fog Transport in a Horizontal Channel
Authors: Grich Nihel , Foudhil Walid , Harmand Souad , Ben Jabrallah Sadok
Published: December 2020

Water spraying in exchanger systems is widely used to allow cooling and improving their performance. However, transfers within the spray mixture are difficult to express because the combined mass and heat are transferred between phases, which complicates the design of the spray systems. This article presents a numerical study of the influence of water volume fraction on the distribution of the temperature in a canal. A 2D numerical model of a horizontal channel was generated and the equations governing the continuous phases (air) and the dispersed phase (water) were developed. These equations were solved using Comsol multiphysics. A comparison of the simulation results and those of the experiment reveals an acceptable concordance.
Neurotrophic Properties of Silexan, an Essential Oil from the Flowers
of Lavender-Preclinical Evidence for Antidepressant-Like
Properties
Authors: Friedland Kristina , Silani Giacomo , Schuwald Anita , Stockburger Carola , Koch Egon , Nöldner Michael , Müller Walter E.
Published: December 2020

Background Silexan, a special essential oil from flowering tops of
lavandula angustifolia, is used to treat subsyndromal anxiety disorders. In
a recent clinical trial, Silexan also showed antidepressant effects in
patients suffering from mixed anxiety-depression (ICD-10 F41.2). Since
preclinical data explaining antidepressant properties of Silexan are
missing, we decided to investigate if Silexan also shows antidepressant-like
effects in vitro as well as in vivo models.

Methods We used the forced swimming test (FST) in rats as a simple
behavioral test indicative of antidepressant activity in vivo. As
environmental events and other risk factors contribute to depression through
converging molecular and cellular mechanisms that disrupt neuronal function
and morphology—resulting in dysfunction of the circuitry that is
essential for mood regulation and cognitive function—we investigated
the neurotrophic properties of Silexan in neuronal cell lines and primary
hippocampal neurons.

Results The antidepressant activity of Silexan
(30 mg/kg BW) in the FST was comparable to the tricyclic
antidepressant imipramine (20 mg/kg BW) after 9-day
treatment. Silexan triggered neurite outgrowth and synaptogenesis in 2
different neuronal cell models and led to a significant increase in
synaptogenesis in primary hippocampal neurons. Silexan led to a significant
phosphorylation of protein kinase A and subsequent CREB phosphorylation.

Conclusion Taken together, Silexan demonstrates antidepressant-like
effects in cellular as well as animal models for antidepressant activity.
Therefore, our data provides preclinical evidence for the clinical
antidepressant effects of Silexan in patients with mixed depression and
anxiety.
Evaluation of Angiogenic Factors (PlGF and sFlt-1) in Pre-eclampsia Diagnosis
Authors: Sá Catherine Primo Nogueira de , Jiménez Mirela Foresti , Rosa Marcos Wengrover , Arlindo Ellen Machado , Ayub Antonio Celso Koehler , Cardoso Rodrigo Bernardes , Kreitchmann Régis , El Beitune Patrícia
Published: December 2020

Objective Recent observations support the hypothesis that an imbalance between angiogenic factors has a fundamental role in the pathogenesis of pre-eclampsia and is responsible for the clinical manifestations of the disease. The goal of the present study was to evaluate the sensitivity, specificity, and the best accuracy level of Soluble fms-like tyrosine kinase-1 (sFlt-1), placental growth factor (PlGF), and sFlt-1/PlGF ratio in maternal serum and protein/creatinine ratio in urine sample to define the best cutoff point of these tests to discriminate between the patients with gestational hypertension and the patients with pre-eclampsia, to evaluate the possibility of using them as diagnostic methods.

Methods A prospective longitudinal study was performed, and blood samples were collected from 95 pregnant patients with hypertension to measure serum concentrations of biomarkers sFlt-1 and PlGF. Urine samples were collected for protein screening. Significance was set as p < 0.05.

Results The sFlt-1/PlGF ratio demonstrated a sensitivity of 57.5% and a specificity of 60% using 50.4 as a cutoff point. The test that showed the best accuracy in the diagnosis of pre-eclampsia was protein/creatinine ratio, with a sensitivity of 78.9% and a specificity of 70% using 0.4 as a cutoff point and showing an area under the receiver operating characteristic curve of 0.80 (p < 0.001).

Conclusion No studied laboratory test proved to be fairly accurate for the diagnosis of pre-eclampsia, except for the protein/creatinine ratio. The evidence is insufficient to recommend biomarkers sFlt-1 and PlGF to be used for the diagnosis of pre-eclampsia.
Quality of the Italian Websites for Parental Guidance on the Indications for Tonsillectomy in Children
Authors: Corrêa Camila de Castro , Piña Sofia Prata , Evangelisti Melania , Villa Maria Pia , Weber Silke Anna Theresa
Published: December 2020

Introduction The quality of information on websites about tonsillectomy regarding the knowledge level may be low. Tonsillectomy is a surgical procedure to hypertrophy of the palatine and pharyngeal tonsils. So, it is an invasive procedure with possible complications, which creates insecurity in parents. Significantly, Internet searches have been increased to address possible health concerns, questioning the quality of websites about tonsillectomy.

Objective To evaluate the readability, reliability, and comprehensiveness of the Italian websites dedicated to parental guidance regarding the indications for tonsillectomy in children.

Methods The search engine
google.it
was used to search the websites. The Gulpease index, which is a widely used readability formula ranging from 0 (difficult) to 100 (easy readability), was employed to evaluate these websites. The Health on the Net Code of Conduct (HONcode) was used to assess the quality of information, by taking ethical principles into account, with values ranging from 0 to 13. The content comprehensiveness of the web pages was assessed by assigning points ranging from 1 (very insufficient) to 5 (very satisfying) to each page. A final comparison with previous studies on tonsillectomy published on websites from other countries was performed.

Results Fourteen Italian websites were selected, and the Gulpease index showed a mean average of 40.77 ± 8.45. The mean of the HONcode analysis was 6.00 ± 1.92, in which the principles with the poorest scores were Attribution and Update. As far as the comprehensiveness of the websites is concerned, the resulting mean was 2.57 ± 0.77, in which Indications was the topic with the highest mean, whereas Benefits was the one with the lowest.

Conclusion The Italian websites were characterized by a lower readability level, a middle position regarding ethical principles, and the same (insufficient) comprehensiveness of tonsillectomy when compared with websites from different countries.
Embolization in Patient with Hypovolemic Shock after Transobturator Sling Procedure
Authors: Arruda Germano José Ferraz de , Bonfitto Miguel , Arruda Neto Jerônimo Ferraz de , Spessoto Luis Cesar Fava , Arruda José Germano Ferraz de , Fácio Fernando Nestor
Published: December 2020

The placement of a suburethral sling is standard treatment for stress urinary incontinence. The transobturator technique (TOT) emerged as an alternative to minimize the risks of the blind insertion of needles, leading to a lower rate of perforation complications compared with the retropubic approach. We present a case of injury to a branch of the left obturator artery following the placement of a urethral sling using TOT, followed by intense bleeding and hemodynamic instability, which was treated with embolization.
Urinary Incontinence and Overactive Bladder Symptoms in Women with Breast Cancer Being Treated with Oral Hormone Therapy
Authors: Stahlschmidt Rebeca , Ferracini Amanda Canato , Medeiros Luana Moreira de , Souza Cinthia Madeira de , Juliato Cassia Raquel Teatin , Mazzola Priscila Gava
Published: December 2020

Objective The objective of the present study is to observe the frequency and severity of urinary symptoms in women with breast cancer (BC) being treated with oral hormone therapy, associating them to drug adherence.

Methods The participants were interviewed once from June to October 2016. The evaluation of urinary symptoms was performed by two questionnaires: International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF) and International Consultation on Incontinence Questionnaire Overactive Bladder Module (ICIQ-OAB). Adherence was evaluated by the Morisky-Green method. Statistical analysis was performed by the Mann-Whitney test, linear regression, and Spearman correlation.

Results Fifty-eight women were interviewed: 42 treated with tamoxifen and 16 with aromatase inhibitor. Twenty-seven women (46.5%) presented urinary incontinence symptoms and 15 (25.8%) presented stress urinary incontinence (SUI). Fourteen (24.1%) women had symptoms of overactive bladder (OAB). There was no statistical difference in symptoms between both treatments and duration of treatments. Higher scores in the ICIQ-SF questionnaire were associated with low/medium adherence and advanced age. Higher scores in the ICIQ-OAB questionnaire were associated with low/medium adherence.

Conclusion The present study showed a high prevalence of urinary symptoms, such as urinary incontinence and OAB, associated with low/medium adherence and older age in women with BC being treated with oral hormone therapy. Health professionals should be alert to these symptoms since it could influence life quality and adherence to treatment.
Pursuit of the Abscopal Effect
Authors: Romesser Paul B. , Crane Christopher H.
Published: December 2020

Evasion of immune recognition is a hallmark of cancer that facilitates tumorigenesis, maintenance, and progression. Systemic immune activation can incite tumor recognition and stimulate potent antitumor responses. While the concept of antitumor immunity is not new, there is renewed interest in tumor immunology given the clinical success of immune modulators in a wide range of cancer subtypes over the past decade. One particularly interesting, yet exceedingly rare phenomenon, is the abscopal response, characterized by a potent systemic antitumor response following localized tumor irradiation presumably attributed to reactivation of antitumor immunity.
Does Caffeine Intake Increase the Incidence of Tinnitus? A Systematic Review
Authors: Aljuaid Sattam M. , Mirza Ahmad A. , Habib Lura A. , AlHarthi Lujain A. , Alansari Bashayer M. , AlQahtani Bashaier G. , Althobaiti Youssef A.
Published: December 2020

Introduction Excessive caffeine intake has been thought to be a contributory factor for tinnitus. However, there has been no systematic review to elucidate the causal relationship between caffeine intake and the incidence of tinnitus.

Objectives We performed the current review aiming at evaluating the evidence from the current literature for the relationship between caffeine intake and the incidence of tinnitus.

Data Synthesis Databases including PubMed, Scopus, and Google scholar were searched for relevant articles. A total of 142 studies were screened for eligibility, of which four articles met our inclusion criteria: two were prospective cohorts and two were cross-sectional studies. Although one study found no association between caffeine consumption and the incidence of tinnitus, an inverse relationship was reported by two population-based studies. Concerning patients with preexisting tinnitus, reduction of caffeine intake in a subset who consumed 150 ml to 300 ml/day of coffee yielded a favorable outcome in tinnitus severity. However, those with higher dose intake were less prone to have improvement in the severity of tinnitus.

Conclusion Although the current review was inconclusive, it appears that the incidence of tinnitus in previously unaffected individuals might be prevented by a high dose of caffeine intake. However, in preexisting tinnitus, a high dose of caffeine may adversely interfere with the efficacy of caffeine reduction.
Ocean acoustics in the changing Arctic
Authors: Worcester Peter F. , Ballard Megan S.
Published: December 2020

Recent changes in ice cover and ocean stratification have been so large that acoustic measurements made during the Cold War no longer reflect current conditions.
Using deep neural network model to predict the plastic behaviour of DP780 steel under complex loading
Authors: Fu Zemin , Xiong Pengpeng
Published: December 2020

In the forming process of sheet metal, the sheet would be subjected to a complicated loading history. The change of pre-strain and the change of strain path might be concentrated in the sheet metal forming process. Through the tensile-tensile experiment of dual-phase (DP780) sheet steel, the flow stress-strain curve obtained shows the cross effect and permanent hardening behaviour. In order to predict the flow stress of DP780 sheet steel under different pre-strain, strain and strain paths, a deep neural network model is established. The data set is divided into training set, validation set and test set to train, verify and test the deep neural network model. The correlation coefficient between the test set prediction results and the experimental results is 98.88%, and the deep neural network model has great predictive ability. Simultaneously, the deep neural network accurately predicts the cross effect and permanent hardening behaviour of DP780 steel.
Research on Mobile Robot Positioning and Navigation System Based on Multi-sensor Fusion
Authors: He Cheng , Ma Renjie , Qu Huaying , Gu Runwei
Published: December 2020

The mobile robot integrates walking and operation functions, which can greatly expand the application range of traditional industrial robots. Aiming at the shortcomings of single sensor positioning under unknown indoor environment, such as large accumulated error and environmental limitations, a multi-sensor fusion positioning navigation system is designed to improve the positioning accuracy of autonomous navigation of mobile robots. The mobile robot uses the laser sensor as the core sensor to obtain two-dimensional information of the environment and realize real-time display of algorithms and interfaces such as map construction, positioning and navigation. The data results of the indoor navigation experiment show that the system has good robustness. At the same time, the feasibility and reliability of the system are verified.
Research on Supply Chain Management Information System of Foreign Trade Enterprises Based on Artificial Intelligence
Authors: Yan Zhang
Published: December 2020

Supply chain management plays an important role in the economic benefit growth and market competitiveness of foreign trade enterprises. At present, it is found from various information statistics that most foreign trade companies are still in exploratory for their understanding of supply chain management without establishing a complete system. Under the background of artificial intelligence (AI) technology, enterprises should actively introduce various high-end technical means, build scientific and technological systems and then enhance their core competitiveness. Companies can independently research and develop expert systems to collect various information and data, perform scientific reasoning, solve some economic problems, and expand the scope of trade.
The Influence and Countermeasures of Enterprise Marketing Activities under the Big Data Background
Authors: Nan Wang , Xiaochun Shi
Published: December 2020

The rapid development of Internet information technology has greatly changed people’s daily work and life patterns, and has produced a new type of economy-the network economy, which has brought new opportunities and challenges to traditional enterprise marketing methods. Enterprises can obtain a large amount of data information based on online sales. How to make full use of data information in the context of big data, seize opportunities, and actively transform has become a hot spot for many enterprises. The article will give a brief overview of the big data background and network economy, and analyze the impact of big data on enterprise marketing activities, and finally propose optimization strategies to help the relevant.
The Development of Machinery Manufacturing And the Application Analysis of Artificial Intelligence
Authors: Xingyu Chen , Chuntang Cai
Published: December 2020

Mechanical manufacturing and artificial intelligence (AI) are important applied technologies in the new era, and they are also part of the market structure. Under the background of the modern information technology, large-scale machinery manufacturing has undergone tremendous changes. Enterprises have begun to use AI technology and discard traditional manufacturing methods, and improve work efficiency. AI is a digital system with an important guiding role for machinery manufacturing. Enterprises should skillfully apply AI technology to promote the machinery manufacturing.
Big data collection and application based on 5G Industrial Internet Three-level edge layer
Authors: Yang Qingfeng , zhang Chonghao , Hu Chunfen , Zhou Haifei , Lou Hua
Published: December 2020

The project is based on 5G+ Industrial Internet to collect the “three-level” edge layer: equipment integration and multi-source heterogeneous data of spare parts manufacturers, equipment manufacturers and equipment users, complete the assimilation of multiple heterogeneous data, establish a unified data standard, and eliminate Discrete enterprise characteristics. Focusing on the informatization of upstream power equipment which is taking into account the informatization of downstream inventory power equipment and realize a large-scale and shallow informatization project of incremental equipment in the Yangtze River Delta in a short period of time, thereby helping companies build general services at the SaaS layer around equipment data. Develop the best process plan to serve enterprise customers in the industry.
Non-fragile infinite time control for networked Lipschitz nonlinear system
Authors: Ma Weiguo , Xu Xia
Published: December 2020

The non-fragile infinite time control is investigated for networked Lipschitz nonlinear system with quantization and incomplete sensor data in this paper. The state of the system is quantized before transmitted to the controller over the network. The Markov Chain is adopted to describe the transmission process. The non-fragile infinite time controller which makes the system stable and performance index minimum is designed in form of linear matrix inequality. A numerical example is given to demonstrate the effectiveness of the proposed method.
Research on sentiment classification of Chinese short text
Authors: Zhu Zhichao , Zhu Zui , Zhu Wenjun
Published: December 2020

Sentiment classification can be widely used in various fields because of the value it has gained, and has received extensive attention in recent years. No matter the traditional methods based on language rules, machine statistical learning, or the current popular deep learning have achieved great success in this respect, but up to now, because of the particularity of Chinese, there are still few methods for Chinese text sentiment classification. Moreover, the traditional method is time-consuming and labor-consuming, with poor versatility. The neural network method saves resources and is generally applicable, but the application of language knowledge is not sufficient. For this reason, we propose a method combining traditional method with neural network, which combines sentiment lexicon, attention mechanism and stacked BILSTM. Word vectors are generated using word2vec, and the context semantics are captured multiple times by stacked BILSTM to get richer semantic information, for sentiment classification, sentiment words often have more influence on the result of classification, so we use sentiment lexicon which contains rich sentiment word to monitor the attention mechanism, and make the attention model pay more attention to sentiment words. Combining the advantages of traditional methods and neural networks, we use the proposed method to do the sentiment binary classification experiments on two data sets. The experimental results show that our proposed method is superior to the previous method.
End-to-End Deep Residual Network for Semantic Segmentation
Authors: Zhou Yingzi , Huang Kun , Guo Xiaoying , He Xiaohai
Published: December 2020

Recent work has made significant progress in improving for the pixelwise labeling with convolutional neural networks by using residual networks. In this paper, we explore the impact of residual network in semantic segmentation by residual encoder-decoder model. The residual block can improves the dimension of feature maps, and obtains more efficient feature maps, and then ensures the effective of deep network structure. Moreover, we select the activat ion function with zero-centered characteristics to speed up the model convergence. The SELU activation function is used to remove the BN function in the network due to normalized deploy ment, thereby reducing the amount of network calculations. The proposed residual encoder-dec oder model can still output high-precision prediction results without any post-processing, and t he convergence speed is significantly faster. Our approach has achieved 61.13% mIoU, 86.92% PA, 73.42% MPA on Camvid dataset.
Dynamic Gesture Recognition Based on iCPM and RNN
Authors: Weihui Chen , Yichao Fan , Ye Zhang
Published: December 2020

Aim to solve the problem that continuous complex actions are difficult to be recognized by computer vision technology in actual production, this paper collects gesture video from single-and double-viewpoint, constructs gesture joint point coordinate recognition network model by improved Convolutional Pose Machine(iCPM) model, obtains gesture Gauss heat map and joint point coordinates in each frame of video, and then inputs joint point coordinates with time series into gesture sequence recognition network. Finally, the gesture sequence is obtained. The experimental results show that the recognition accuracy of gesture recognition model based on double-viewpoint is 4.18% ∼ 6.92% higher than that of the single-viewpoint gesture recognition model, which verifies that the gesture recognition model based on dual-viewpoint has better recognition effect. In addition, the video samples of Tin-Lead Soldering including continuous and complex actions verify that the model has ideal recognition ability for dynamic gesture in actual production process.
Multi-Agent Online Coordination via Bayesian Inverse Planning
Authors: Wang Meiming , Lan Long , Yang Wenjing
Published: December 2020

Multi-agent coordination is a classical applied engineering problem and has been widely used in daily life. To efficiently coordinate all agents in the environment, most traditional models rely on a robust communication system between agents. However, in the scenario of autonomous vehicles, building a reliable communication system is extremely expensive and is very difficult to achieve in the foreseeable future. In this paper, we propose an online multi-agent coordination mechanism for each agent in the absence of communication and explore the benefits of Bayesian inverse planning in achieving the Nash equilibrium which provides an optimal coordination solution for each participant in multi-agent environment. By deliberate design, the proposed Bayesian inverse planning enables each independent agent to infer goals and predict future actions of other agents only by simply observing the past actions of them. To make a timely response to the dynamic environment, the inferences and predictions can be flexibly adjusted accordingly with the continuously updated action information of agents. Based on future action predictions, agents take coordinated actions to achieve Nash equilibrium coordination. We designed several mixed driving scenarios in the real world to test our model, and simulation results show that our model is efficient and flexible, compared with an optimal model and a heuristic model.