bluuebunny/crossref_metadata_2025 huggingface dataset:
Physico-mechanical properties of lime–silica fume pastes modified with nano-metakaolin
Authors: Al-Jabri Khalifa , Shoukry Hamada , Abdel Aal Ahmed
Published: March 2019

The improvement in the physico-mechanical properties of lime–silica fume (SF) pastes through the incorporation of nano-metakaolin (NMK) was investigated. Lime–SF paste (1 : 1 by weight) was prepared as a reference binder. To examine the influence of NMK on strength development, SF was replaced with 2–10 wt% NMK. The compressive strength, capillary water absorption and pore structure of the designed mixes were determined after 3, 7 and 28 d of curing. X-ray diffraction analysis and differential scanning calorimetry were used to study the phase composition and scanning electron microscopy (SEM) was used for microstructural investigations. The lime–SF binder modified with 6% NMK exhibited the best mechanical performance. Pore structure analysis confirmed that NMK provided significant refinement in the pore structure of the blended pastes and SEM micrographs revealed noticeable microstructural improvements. The capillary water absorption coefficient decreased considerably with an increase in NMK content up to 6% compared with the reference mixture. Use of the developed lime–SF–NMK paste is recommended as a promising innovative binder for specific cement applications such as plastering and renovation of buildings.
Assessing interactional skills in a paired speaking test
Authors: Borger Linda
Published: March 2019

The operationalization of interactional competence (IC) within the paired speaking test format allows for a range of interactional skills to be tested. However, in terms of assessment, challenges are posed with regard to the co-constructed nature of IC, making investigations into raters’ perceptions of the construct essential to inform test score interpretation. This qualitative study explores features of IC that raters attended to as they evaluated performances in a paired speaking test, part of a Swedish national test of English as a Foreign Language (EFL). Two groups of raters, 17 EFL teachers from Sweden, using national standards based on the Common European Framework of Reference for Languages (CEFR), and 14 raters from Finland and Spain, using CEFR scales, rated six audio-recorded paired performances, and provided written comments to explain their scores and account for salient features. The findings of the content analysis indicate that raters attended to three main interactional resources: topic development moves, turn-taking management, and interactive listening strategies. As part of the decision-making process, raters also considered the impact of test-takers’ interactional roles and how candidates’ performances were interrelated. In the paper, interaction strategies that were perceived as more or less successful by raters are highlighted. The findings have implications for our understanding of raters’ operationalization of IC in the context of paired speaking tests, and for the development of rating scales and guidelines that reflect the social dimensions of the construct.
producción de maíz en Sinaloa, México, y sus implicaciones para el medio ambiente/ The Production of Corn in Sinaloa, Mexico and its Implications for the Environment
Authors: Cruz Delgado Daniela , Leos Rodríguez Juan Antonio
Published: March 2019

La sustitución de cultivos acarrea problemas de contaminación al ambiente, principalmente al suelo y agua. El objetivo de este artículo es analizar la evolución de la producción de maíz blanco en Sinaloa y sus implicaciones para el ambiente, derivadas de la sustitución de cultivos. La metodología empleada es el cálculo del número índice de crecimiento de la producción y la superficie sembrada de maíz, por grupos de cultivos y los cinco cultivos básicos en Sinaloa. El periodo analizado, de 1980 a 2016. Sinaloa se ha convertido en el principal productor de maíz blanco en las últimas décadas; su cultivo es intensivo en agroquímicos, lo que puede ocasionar problemas de contaminación al suelo y agua. La superficie sembrada se incrementó 287 % de 1980 a 2016, especialmente en áreas irrigadas. Cereales y hortalizas son los grupos que más crecieron y representan el 72,9 % del valor de la producción. Los procesos productivos involucran costos ambientales como los resultantes de la aplicación de fertilizantes y plaguicidas, que sin un adecuado control deterioran el suelo, contaminan los mantos freáticos, la flora, la fauna y la salud humana.

Abstract

The substitution of crops leads to problems of contamination to the environment, mainly to soil and water. The objective of this article is to analyze the evolution of the production of white corn in Sinaloa and its implications on the environment, derived from the substitution of crops. The methodology used is the calculation of the index number of growth of the production and the area planted with corn, by crop groups and the five basic crops in Sinaloa. The period analyzed is 1980 to 2016. Sinaloa has become the main producer of white corn in recent decades; its cultivation is intensive in agrochemicals, which can cause pollution problems to soil and water. The planted area increased 287 % from 1980 to 2016, especially in irrigated areas. Cereals and vegetables are the groups that grew the most and represent 72,9 % of the value of production. The productive processes involve environmental costs such as those resulting from the application of fertilizers and pesticides, which, without adequate control, deteriorate the soil, pollute groundwater, flora, fauna and human health.
Interacción de aglutinantes de ﬂuoruro de polivinilideno (PVDF) con soluciones fuertemente alcalinas
Authors: Pagliaro Leonard , A. Lowy Daniel
Published: March 2019

Se propone una metodología para evaluar los fenómenos degradantes de aglutinantes en los medios alcalinos, información que debe de ser de gran ayuda para los expertos en el campo de la investigación y desarrollo de baterías, ya que se podría evaluar la estabilidad esperada de los aglutinantes ﬂuorados antes de ser probados en células galvánica ensambladas. Por esto, se ahorra tiempo, esfuerzo y se agiliza el trabajo. Mientras que el poli (tetraﬂuoroetileno), PTFE, ha demostrado ser químicamente inerte, este plantea un desafío tecnológico severo, siendo difícil de procesar debido a su ﬁbrilación. Los aglutinantes alternos son poli (1, 1-diﬂuoroetileno), PVDF, y sus copolímeros, conocidos bajo el nombre comercial de Kynar R, que son signiﬁcativamente más fáciles de usar. Sin embargo, cuando se mantiene en contacto con soluciones fuertemente alcalinas, la estabilidad química de Kynars se ve comprometida. Estos pueden someterse a reacciones de eliminación con lal iberación de iones de ﬂuoruro y la formación de enlaces dobles. Estosenlacesπpuedendegradarseaúnmásporoxidación,encontactoconoxidantesincorporadosenelcátodo.Estos procesos químicos no deseados pueden inhibir las propiedades aglutinantes y, en última instancia, pueden reducir la vida útil de las células galvánica, agotando el rendimiento de la batería. En este rol, se investigó la descomposición de la aglutinación de PVDF en medios alcalinos siguiendo dos pasos: (i) los aglutinantes puros fueron probados exponiéndolos a 32 wt % solución acuosa de KOH, a 60◦C, temperatura que acelera los procesos degradantes, y (ii) se investigaron los aglutinantes incorporados en la pasta cátodo en condiciones similares. La degradación del aglutinante se evaluó determinando la concentración de iones de ﬂuoruro liberados, monitoreando el cambio de color y la formación de precipitados y grabando e interpretando los espectros FT-IR.
Eficiencia y confiabilidad de modelos de estimación de biogás en rellenos sanitarios
Authors: Escamilla-García Pablo Emilio
Published: March 2019

Este artículo muestra un análisis comparativo de las emisiones de biogás generadas en un relleno sanitario al aplicar el modelo mexicano de biogás, el modelo de la Agencia de Protección Ambiental de los Estados Unidos de América (EPA) y comparar los resultados con datos obtenidos in-situ. Las estimaciones con los modelos teóricos y la medición en campo se realizaron en 36 pozos de venteo de un relleno sanitario ubicado en el Estado de México, México, con una recepción diaria de 3500 kilogramos de RSU. Los resultaron in-situ mostraron una generación de biogás (CH4, CO2 y O2) con una frecuencia media de 35.44 Hz (1/s) y emisiones de metano de 3355.99 m3 /hr. En contraste los modelos teóricos estimaron valores para el año 2018 de 6270.57 m3/hr para el modelo de la EPA y 8379.52 m3/hr para el modelo mexicano de biogás. Los resultados mostraron variaciones significativas en las estimaciones de los modelos teóricos versus la medición in-situ. La información generada permite discutir la confiabilidad del uso de modelos teóricos para formular proyectos de aprovechamiento y valorización de RSU al considerar los altos montos de inversión que implican y que las proyecciones de generación de energía se basan en la frecuencia de generación del flujo de biogás estimado en el relleno.
Estimation of the Water Balance of a Small Tropical Andean Catchment
Authors: Duque-Sarango Paola Jackeline , Cajamarca-Rivadeneira Ronald , Wemple Beverley C. , Delgado-Fernández Manuel E.
Published: March 2019

The present study seeks to estimate the water balance that results as a product of the variation of precipitation and temperature over the Chaquilcay microcatchment, a natural system that intercepts with the surface of the Aguarongo Protected Forest in Gualaceo, Ecuador. Four meteorological stations of the National Institute of Meteorology and Hydrology (INAMHI) were studied, which are divided into climatological and pluviometric, with time series of over 30 years, (1982-2015 period). In order to quantify the contributions and losses of water, statistical analyzes of the time series and surveys of in situ information were carried out. The methods used are linear regression, streak test and double mass curve. To fill and validate the series of precipitation and temperature, reference temperatures of the isothermal raster of Ecuador were included in the pluviometric stations. Additionally, a digital elevation model (MDE) was used to predict the amount of sunshine, and the Thornthwaite evapotranspiration method (1948) was applied from the obtained data. The results show acceptance of the meteorological records, while in the soil analysis we obtained the following data: Humidity, 62.38%; organic matter, 21.29%; field capacity, 18.71 mm and a flow of 1.89 m³ / s during the month of May. Finally, the water balance indicates 843.7 mm of annual precipitation, a storage difference of 18.71 mm representing 2.22% of total precipitation, an surplus of 144.5 mm, and actual evapotranspiration of 680.5 mm, with 17.13% and 80.65%, respectively.
Cortisol and adrenal androgens as independent predictors of mortality in septic patients_protocol v1
Authors: De Castro Rocío , Ruiz David , Lavín Bernardo-Alio , Ángel Lamsfus Jose , Vázquez Luis , Montalban Coral , Marcano Gilberto , Sarabia Raquel , Paz María , Blanco Cristina , Santibáñez Miguel
Published: February 2019

Objective: To determine the prognostic value of cortisol, Dehydroepiandrosterone (DHEA) and Dehydroepiandrosterone-sulfate (DHEAS), together with their ratios (cortisol/DHEA and cortisol/DHEAS), as independent predictors of mortality in septic patients. Methods: Prospective cohort study of 139 consecutive patients with a diagnosis of severe sepsis or septic shock. Adrenal hormones were determined within the first 24 hours of the septic process. To determine and compare the predictive ability of each marker for the risk of unfavorable evolution (in-hospital, 28-day and 90-day mortality), ROC (Receiver Operating Characteristic) curves were constructed and the area under the curve (AUC) was determined. As measures of association, adjusted odds ratios (OR) with their 95% confidence intervals (95%CI) were estimated by unconditional logistic regression. Cortisol, DHEA and DHEAS results were compared to lactate, CRP, SOFA and APACHE II Scores. Results: Cortisol showed the best predictive ability, with AUCs of 0.758, 0.759 and 0.705 for in-hospital mortality, and 28-day and 90-day mortality, respectively; whereas AUCs for 28 days mortality for SOFA and APACHE II scores, and other biomarkers studied, such as Lactate or CRP, were 0.644, 0.618, 0.643 and 0.647, respectively. Associations between high cortisol levels (>17.5 µg/dL) and mortality were strong and statistically significant for in-hospital and 28-day mortality: adjusted ORs 10.13 and 9.45 respectively, and lower for long term mortality (90 days): adjusted OR 4.26 (95% CI 1.34-13.56), p trend 0.014. Regarding adrenal androgens, only positive associations were obtained for DHEAS and most of these positive associations did not yield statistical significance. Regarding Cortisol/DHEA and cortisol/DHEAS ratios, they did not improve the predictive ability of cortisol. The only exception was the cortisol/DHEAS ratio, which was the best predictor of mortality at 90 days (AUC 0.737), adjusted OR for highest cortisol/DHEAS ratio values 6.33 (95%CI 1.77-22.60), p trend 0.002. Conclusion: Basal cortisol measured within the first 24 hours of the septic process was the best prognostic factor for in-hospital and 28-day mortality, even superior to the Sequential Organ Failure Assessment (SOFA) or Acute Physiology and Chronic Health Evaluation II (APACHE II) scores. The cortisol/DHEAS ratio was an independent predictor of long-term mortality
La technique du collage : une stratégie esthétique et un procédé littéraire dans “Terrasse à Rome“ de Pascal Quignard
Authors: BEKHEDIDJA Nabila
Published: March 2019

RÉSUMÉ. Pascal Quignard crée une structure en morceaux dans Terrasse à Rome, avec l’utilisation d’un procédé proche des arts plastiques : le collage. Le collage désigne le fait d’introduire dans une œuvre des fragments qui ne lui appartiennent pas (extraits de textes littéraires, écriture en italique, écriture étrangères, inventaire, versets bibliques, etc.).Une approche immanente mettra en exergue une structure romanesque éclatée dans laquelle se présente une  diffraction narrative et textuelle .L’objectif de cette étude est d’expliquer le rôle de la technique du collage dans la création d’un effet hybride et hétéroclite qui exige la participation du lecteur pour rassembler les éléments  éparpillés de l’histoire racontée. Mots-clés : collage -hétéroclite - hybride-lecteur-reconstitution.ABSTRACT. Pascal Quignard creates a structure in pieces in Terrasse à Rome, using a process close to the plastic arts: collage. Collage refers to the introduction into a work of fragments that do not belong to it (excerpts from literary texts, italic writing, foreign writing, inventory, biblical verses, etc. ) An immanent approach will highlight a fragmented novel structure in which there is a narrative and textual diffraction. The objective of this study is to explain the role of the collage technique in creating a hybrid and heterogeneous effect that requires the reader's participation to bring together the scattered elements of the story being told. Keywords: collage - heteroclite - hybrid - reader-reconstitution.
Influence of Clay on Time Domain Induced Polarization
Authors: Yatini Yatini
Published: March 2019

The main problem in mineral exploration is how to determine the existence of deposits at subsurface based on resistivity and chargeability parameters. Clay almost exists in rocks. Here, this study was to understand the influence of clay on time domain induced polarization. To clarify the clay parameters, field physical modeling was conducted. The results showed physical modeling data of 20-cm diameter spherical target with a total content of 28.3% of iron did not show any significant response. The high content of clays on the medium used in field physical modeling seems to be the main reason for the change in sample. In the case of the subsurface spherical model that is near to the soil medium, the presence of clay leads to the medium resistivity value to be identical to the target value. As a consequence, the resistivity response can not be identified clearly. The chargeability between the medium and the target remains small but the chargeability response remains constant.
Los ecos de las trece colonias. De los impuestos con representación a la participación en los impuestos
Authors: Rúa Serna Juan Camilo
Published: March 2019

El artículo se propone mostrar cómo ha sido la participación de la sociedad civil en la estructuración de la capacidad fiscal del Estado colombiano. Para ello se revisan procesos de constitucionalidad en los que se hayan demandados normas fiscales, para determinar el nivel de incidencia de los mecanismos de participación ciudadana en la capacidad tributaria del Estado. Mediante análisis básicos de estadística descriptiva y análisis de contenido de los documentos preparatorios de la Constitución Política, se llega a la conclusión de que herramientas de participación ciudadana como la acción pública de inconstitucionalidad han abierto importantes oportunidades para la destrucción y modificación de normas tributarias, lo que sería impensable bajo una democracia estrictamente representativa.
Crónica de un cambio anunciado. Las elecciones de 2017 en Chile frente al cambio de sistema electoral
Authors: Cruz Facundo , Varetto Carlos
Published: March 2019

Este artículo se enfoca en el análisis de las elecciones presidenciales en Chile de 2017 en perspectiva comparada desde el retorno a la democracia en 1989, en el que se sostiene que el sistema partidario se encuentra en una nueva etapa de su trayectoria que comienza en 2013 y en la que ambos sistemas partidarios —presidencial y legislativo— comienzan a confluir nuevamente en lo que respecta a sus niveles de fragmentación y volatilidad electoral. Es posible que este nuevo formato y una nueva dinámica competitiva tiendan a consolidarse. De esta manera, se estaría dando lugar a una tercera etapa. La primera del sistema partidario chileno tuvo lugar entre 1989 y 2005 caracterizada por la estabilidad, baja fragmentación y alta institucionalización. La segunda transcurrió entre 2005 y 2013, en la que se destaca un desajuste entre competencia presidencial —progresivamente más volátil y fragmentada— y legislativa —aún estable y menos fragmentada—.
Cotización del petróleo y volumen de acciones de aerolíneas latinoamericanas 2011-2015: análisis de correlación bivariada
Authors: Espinal Zapata Leidy Johana , Sánchez Toro Moisés , Zapata Ruiz Natalia
Published: March 2019

El presente artículo tiene como objetivo analizar la influencia del precio del petróleo en el costo y volumen de las acciones de aerolíneas latinoamericanas en el periodo 2011-2015; para lograr esto, después de realizar una revisión de la literatura más relevante sobre el tema, analizar el comportamiento de las acciones de seis aerolíneas (Volaris, LAN, Gol, Copa, Avianca y Aeroméxico) y el precio del petróleo en las referencias BRENT y WTI, se aplicó un análisis de correlación bivariada. Según los análisis se concluye que la fluctuación del precio del petróleo, una de las principales materias primas en la aviación, afecta de manera negativa el precio y volumen de las acciones y repercute en la economía y finanzas de las aerolíneas y el desempeño del sector. Este estudio tiene implicaciones para las aerolíneas, los analistas y académicos que siguen el comportamiento de estas compañías.
Proceso de implementación de las NIIF en Colombia: un acercamiento a las autoridades de vigilancia definidas en la ley 1314 de 2009
Authors: Botero Bedoya Ángela Susana , Marulanda Tejada Camilo , Muñoz Osorio Lina María , Álvarez Osorio Martha Cecilia
Published: March 2019

Las Superintendencias y la Junta Central de Contadores, definidas en la Ley 1314 como autoridades de supervisión y autoridad disciplinaria, respectivamente, se convierten en un actor clave en el proceso de convergencia hacia Estándares Internacionales de Información Financiera, al ser las entidades responsables de vigilar el cumplimiento del mismo; sin embargo, es cuestionable el rol desempeñado por dichas autoridades y la ejecución a cabalidad de sus funciones. Para caracterizar el papel que han jugado se aplicaron entrevistas a personas vinculadas directamente con las autoridades en mención y encuestas a contadores con experticia en el tema, evidenciando que tales autoridades han presentado falencias que tienen un carácter histórico y que han dificultado la vigilancia del proceso de convergencia, puesto que la Junta Central de Contadores desde su creación ha funcionado reactivamente y la Superintendencia de Sociedades no logra dar cubrimiento a la multiplicidad de entidades.
Social Work on the Whiteboard: Governing by Comparing Performance
Authors: Hjärpe Teres
Published: March 2019

This article explores a number-based comparative logic unfolding around a particular kind of meeting in a social work setting: a daily and short gathering referred to as a “pulse meeting”. At such meetings, staff gather around a whiteboard visualizing individual statistics in terms of the number of client meetings performed or assistance decisions made. The statistics function as a basis for further division of work tasks. As such, it is a particular way of representing what social workers do at work. Ethnographic fieldwork conducted in the social services revealed how such openly exposed individual performance and the related number-based comparative logic can trump alternative logics ranging from the overall collective performance, competing views on clients’ needs and efficiency, and the social worker’s sense of professionalism. When participants of the study compared themselves to each other and in relation to standards and goals, certain conclusions were drawn about what should be done by whom and in what order. Such conclusions became embedded in an objectivity status difficult for anyone to argue against. Finally, the number-based logic also found its way into the counter-practices formulated by social workers unsatisfied with what was visualized on the whiteboard.
Key milestones of the negotiating process on the accession of Croatia to the EU in 2007 – 2008
Authors: Horopakha Serhii
Published: March 2019

On 1st July 2013, the Republic of Croatia officially became the 28th member of the European Union. This event marked the fulfillment of a foreign policy goal, along with joining NATO in 2009, as a major step forward in the country’s long-term consolidation process.

The article therefore analyzes the key events of the Croatia – EU relations in 2007-2008, which moved this Balkan country closer to implementing its Euro-integration course. Particular attention is paid to the peculiarities of the pre-accession negotiations with the European Union, as well as to internal and foreign policy factors that had a direct impact on the Euro-integration dialogue between Croatia and the European Union. In this context, emphasis is placed on problem issues that slowed down the dynamics of the negotiation process to a certain extent, in particular the unilateral application by Croatia of the Ecological and Fisheries Protection Zone, and measures taken by the Croatian authorities to settle them.

Significant achievements of Croatia in the negotiation process with the European Union are highlighted, in particular, progress of the country in meeting the European Union criteria as well as a date determination the of pre-accession negotiations completion as an important political sign of the European Union readiness to accept a new member in future.
Practical aspects of diagnosis and treatment of neonatal seizures
Authors: Morozova E. A. , Sergeeva R. R. , Morozov D. V.
Published: March 2019

Aim– analyze the current practice of management in patients with neonatal seizures and perinatal brain disorders, and determine the ways to prevent long-term neurological complications.Materials and methods.The study group included 140 children (aged from 2 weeks to 18 months) with neonatal seizures and perinatal brain abnormalities. In these cases, the obstetric and early postnatal history was analyzed; all patients underwent video-EEG monitoring, cervical spine X-ray, neuroimaging, and a Doppler ultrasound test.Results.We found a number of reliable ante- and intra- partum predictors of neonatal seizures. According to the medical documentation from the neonatal pathology departments, local neonatologists have difficulties in diagnosing and verifying the type and duration of seizures. In most patients with neonatal seizures, we detected epileptiform EEG activity, signs of birth defects (according to X-ray) and marked changes (according to neuroimaging) in the cervical spine.Conclusion.The results confirm that neonatal seizures are one of the first symptoms of severe brain damage, including intra-natal damage. Evolution of neonatal seizures into drug-resistant epilepsy and further disability is associated with insufficient knowledge of neonatal seizures, standards for their diagnosis, therapy and multidisciplinary observation.
Research and development of 2-ethyl-6-methyl-3-oxypyridine succinate nano-form for the treatment of epilepsy
Authors: Avakyan G. G. , Voronina T. A. , Nerobkova L. N. , Avakyan G. N.
Published: March 2019

The aimis to develop an antiepileptic drug based on polymer nanoparticles with 2-ethyl-6-methyl-3-oxypyridine succinate to facilitate the drug transport through the blood-brain barrier.

Materials and methods.The nano-drug was created using the biologically active substance 2-ethyl-6-methyl-3-hydroxypyridine succinate and polybutyl cyanoacrylate (PBCA) nanoparticles. The advantages of this nano-form over the active ingredient of the same drug were studied using experimental models: the maximum electroshock test (MES), the antagonism test with corazol, models with a cobaltinduced epileptic focus and secondary generalized convulsions, and models of status epilepticus.

Results.The antiseizure effects of the nanoform on the experimental models of epilepsy are identified.

Conclusion.The nano-drug reduces the number of secondary generalized clonic-tonic seizures by 7.8 times; it also reduces 10-fold the animal mortality and diminishes the seizure manifestations that occur in the interictal period of the epileptic status.
Epilepsy combined with Wolf-Hirschhorn syndrome: a literature review and description of clinical cases
Authors: Mironov M. B. , Chebanenko N. V. , Ayvazyan S. O. , Vladimirova S. A. , Osipova K. V. , Burd S. G. , Rubleva Yu. V. , Krasilshchikova T. M. , Bychenko V. G.
Published: March 2019

This article presents the anamnestic, clinical, electro-encephalographic and neuroimaging findings in 5 patients with epilepsy combined with Wolf-Hirschhorn syndrome (WHS). According to our data and the results of others, this combination has its specific characteristics. These include: a high incidence of epilepsy in patients with WHS (50-100% of cases), an early debut of seizures (mainly in the first year of life), fever-provoked seizures, and a variety of seizure types – focal paroxysms, bilateral tonic-clonic seizures, atypical febrile seizures, atypical absences and epileptic spasms. In addition, there may be frequent epileptic seizures tending toward status epilepticus, a slowing of the major EEG activity, a local EEG slowing (mainly in the posterior and bi-frontal areas), and regional / multiregional epileptiform activity. In more than 50% of cases, the diffuse peakwave activity is observed; the broad spectrum anti-epileptic drugs are highly efficient in 80% of cases. Based on this study, we propose recommendations for the management of patients with epilepsy combined with WHS.
Functional hemispherotomy in the treatment of drug-resistant epilepsy: a clinical case
Authors: Sufianov A. A. , Deniel R. T. , Stefanov S. Zh. , Sufianova G. Z. , Orlov A. S. , Churkin S. V. , Kostarev S. I. , Mirkhaydarov S. V.
Published: March 2019

Though brain hemiatrophy is not among the leading causes of symptomatic epilepsy; the problem remains important and is of great practical interest to neurologists and neurosurgeons in Russia. In this article; we present an example of successful surgical treatment of Dyke-Davidoff-Masson syndrome. Here; functional hemispherotomy was performed in a 22 years old female patient; as a result; the occurrence and intensity of epileptic seizures decreased. This clinical case provides hope for this procedure to show even better results if performed in early childhood.
Presurgical non-invasive diagnosis of focal cortical dysplasia
Authors: Mirkhaydarov S. V.
Published: March 2019

In recent decades, MRI increased the success rate of the diagnosis and surgical treatment of epilepsy. Approximately 30% of patients with epilepsy suffer from the drug-resistant form of this disease. Focal cortical dysplasia is the most common abnormality of cortical development that is often associated with drug-resistance. Surgery has an important role in the treatment of epilepsy caused by focal cortical dysplasia. Focal cortical dysplasia is classified by its morphological characteristics. By large, focal cortical dysplasia can be diagnosed using the up-to-date neuroimaging tools. The aim of that paper is to review the methods available for the diagnosis of focal cortical dysplasia.
Paroxysmal disorders in the long-term after traumatic brain injury in children and adolescents
Authors: Zavadenko N. N. , Nesterovskiy Yu. E. , Kholin A. A. , Vorobyeva I. S.
Published: March 2019

Consequences of traumatic brain injury (TBI) in children and adolescents pose a major medical and social problem, as TBI interferes with neuro ontogenesis. Among these consequences, paroxysmal disorders that manifest in the long-term after TBI represent an important issue. These disorders include posttraumatic headaches, posttraumatic epilepsy and subclinical epileptiform EEG activity. In this review, clinical manifestations, pathophysiology and management of the long-term post-TBI paroxysmal disorders in children and adolescents are discussed.
Diagnostic evaluation of drug-resistant insular epilepsy
Authors: Khachatryan R. G. , Ibatova G. S. , Alekseeva T. M. , Khachatryan W. A.
Published: March 2019

About 30% of patients with temporal epilepsy are resistant to antiepileptic drugs; in such cases, surgical treatment is considered to be the best option. Existence of an extra-temporal epileptogenic focus in the insula is a possible cause of seizures after temporal lobe surgery in about 20% of patients. Because of its localization, the anatomical features of the insular lobe, as well as the entire concept of insular epilepsy have not been well documented. Yet, it has been established that the seizures developing from the insular cortex can mimic the paroxysms arising from the temporal lobe. When the insula is involved in the epileptic process, resection of the insular cortex improves the outcome of surgical treatment. Rational and well-based selection of candidates for surgical treatment is of paramount importance for patients with drug-resistant epilepsy. The article presents a review of the up-to-date literature on this matter.
A comparative study of low doses of intrathecal ketamine and midazolam with bupivacaine for postoperative analgesia in infraumbilical surgeries
Authors: M. Rajabhushanam , K. Sunil Kumar , Aasim Syed Ali , S. Venkatesh
Published: March 2019

Background: Infra-umbilical surgeries may be performed under local, regional (spinal or epidural) or general anaesthesia, spinal block is still a first choice, because of its rapid onset, high quality of blockade, lack of catheter related infection, less failure rate and also cost effective but the duration of block and postoperative analgesia is limited. The purpose of study was to compare the efficacy of adding ketamine to 0.5% hyperbaric bupivacaine with midazolam to 0.5% hyperbaric bupivacaine in elective infraumbilical procedures.Methods: A randomized, single blinded, clinical study. 60 subjects were enrolled from the patients presenting for elective infraumbilical surgeries after following the inclusion and exclusion criteria laid down for the study. Sixty ASA Grade I and II patients undergoing infra umbilical surgeries were randomly divided into one of the two equal groups (n=30).Results: Total 60 patients were included in this study. The mean time to achieve T10 sensory level and modified bromage scale III was prolonged in group M (4.33±1.09, 6.66±1.26 min) as compared to group K (3.3±0.7, 4.96±1.21 min) which was statistically significant (P value <0.05).Conclusions: The present study concludes that addition of intrathecal midazolam to hyperbaric bupivacaine provide very good and prolonged post-operative analgesia without significant intra-operative and post-operative side effects compared to intrathecal ketamine.
DELIMITAÇÃO DE ÁREAS PARA IMPLANTAÇÃO DE ATERRO SANITÁRIO UTILIZANDO METODOLOGIA MULTICRITÉRIOS NO MUNICÍPIO DE GOIÁS, GOIÁS
Authors: Moreita Pedro Augusto Gonzaga , Barberi Maira , De Oliveira Anna Luiza Garção
Published: March 2019

A produção de resíduos sólidos, especialmente os urbanos, constituem uma das atuais preocupações centrais para a governança pública, atingindo não apenas as grandes cidades, mas a todos os núcleos urbanos. Sua destinação final de modo ambientalmente sustentável tem sido amparada por uma ampla gama de leis, resoluções e normativas que auxiliam na seleção de locais apropriados para este fim. Neste ínterim, foram elencados os limites estabelecidos pela Resolução n° 005/2014 CEMAM, Norma Brasileira Técnica n° 10157/1987 que versa sobre os Aterros de Resíduos Perigosos – Critérios para projetos, construção e operação e outras para produção de produção de mapa de classificação de Áreas Favoráveis para a Instalação do Aterro Sanitário de RSU no município de Goiás-GO com o auxílio de ferramentas de geoprocessamento.
O estado da arte das práticas de gamificação no processo de ensino e aprendizagem no ensino superior
Authors: Vieira Alexandre De Souza , Saibert Alexandre Peixoto , Neto Manoel Joaquim Ramos , Costa Thailson Mota da , Paiva Nataliana De Souza
Published: March 2019

Este artigo apresenta os resultados de uma pesquisa bibliográfica cujo objetivo foi sintetizar as práticas de gamificação empregadas no processo de ensino e aprendizagem no ensino superior. Para isso o estudo foi dividido em três partes: (1) compreender o significado de gamificação e suas implicações na educação; (2) investigar as práticas de gamificação voltadas para o ensino superior; (3) analisar as práticas de gamificação no ensino superior. Os procedimentos metodológicos concentram-se na revisão de literatura e estado da arte das pesquisas encontradas com corte longitudinal a partir 2010 nas plataformas do Portal CAPES e Google Scholar. Os resultados gerais da aplicação da gamificação na educação superior são positivos quanto ao aumento da motivação e engajamento dos estudantes nas atividades que foram desenvolvidas. Entretanto, há limitações quanto à implementação dos elementos gamificados. Assim, alunos e docentes devem ser cautelosos, de forma a evitar expectativas irreais quanto aos resultados dos processos gamificados no ensino e aprendizagem.
Satisfação acadêmica em estudantes do Curso de Graduação em Ensino Básico da Universidade Pedagógica - Delegação de Nampula
Authors: Salomão Ivo Félix Caroa de Sousa , Abacar Mussa , Aliante Gildo
Published: March 2019

Este trabalho objetivou avaliar a satisfação com a experiência acadêmica e sua relação com as variáveis sócio demográficas entre estudantes de graduação em Ensino Básico da Universidade Pedagógica em Moçambique, Delegação de Nampula. Trata-se de um estudo descritivo quantitativo. Participaram do estudo 143 estudantes, sendo 44 do sexo masculino e 99 do sexo feminino. Os dados foram coletados por meio de questionário de dados sócio demográficos e da Escala de Satisfação com a Experiência Académica e analisados com recurso ao SPSS. Os resultados mostraram que a dimensão mais crítica da satisfação acadêmica é a de satisfação com o curso, seguida de oportunidades de desenvolvimento e por último com a instituição. 30,1% dos estudantes inquiridos mostra-se pouco satisfeito com o curso; 33,6% satisfeitos com a oportunidade de desenvolvimento e 43,4% sentem-se satisfeitos com a instituição. Nas correlações entre as variáveis sócio demográficas com as dimensões da satisfação acadêmica, a variável sexo demonstrou associação com a oportunidade de desenvolvimento, sendo as mulheres que denotam maior oportunidade de desenvolvimento. A variável idade apresentou associação positiva da satisfação com a instituição, as variáveis “anos de frequência” e “número de vezes que o estudante reprovou”, correlacionaram-se negativamente com as dimensões satisfação com o curso e oportunidade de desenvolvimento, respectivamente. Por fim, o “número de disciplinas reprovadas”, mostrou-se negativamente correlacionado com as dimensões satisfação com o curso e satisfação com a instituição. O conhecimento do nível de (in)satisfação acadêmica e respectivos determinantes pode contribuir para o planejamento e implementação de estratégias que visem a melhoria de qualidade de educação oferecida aos estudantes.
Цифровое здравоохранение: разработка и применение в России
Authors: Русова Виолетта Сёмавна
Published: March 2019

Данная статья направлена на исследование модели цифрового здравоохранения и её применение в современных условиях. Актуальность исследования обусловлена изменением экономической ситуации в стране, в основе которой лежат радикально новые механизмы регулирования системы здравоохранения. В статье представлена модель цифрового здравоохранения, сформулированы задачи и рекомендации по её внедрению. Саморазвивающаяся система, в виде модели цифрового здравоохранения, отвечает на спрос потребителя формированием ценности, посредством максимальной ликвидации всех видов потерь. Цифровое здравоохранение - проект, аккумулирующий данные в цифровом виде от хозяйствующих субъектов, с целью обработки информации и принятия эффективного управленческого решения по вопросу обеспечения государственных гарантий. Разработка и применение цифрового здравоохранения представляет собой инновационную систему управления, которая подразумевает сохранение человеческого капитала. Цифровая модель здравоохранения должна внедряться параллельно существующей модели здравоохранения, постепенно принимая от нее полномочия и функции. Такой процесс внедрения минимизирует потери и формирует культуру бережливого использования ресурсов. С процессами изменения системы одновременно растет информационная прозрачность, формируется диалог между потребителями и производителями медицинских услуг. Эффект от реализации цифрового здравоохранения должен обеспечить улучшение качества жизни и устойчивое развитие, посредством использования результатов инновационной деятельности. Формирование и развитие системы здравоохранение играет ключевую роль в благополучии и стабильности страны. Благодаря использованию цифровых технологий сводятся воедино все информационные системы. Данные технологии позволяют осуществлять актуальный мониторинг, формируя представление о состоянии здоровья населения, о тенденциях и результатах деятельности учреждений здравоохранения.
Феномен уберизации бизнеса и его границы
Authors: Тагаров Бато Жаргалович
Published: March 2019

В данной статье автор анализирует процесс уберизации и определяет основные черты данной бизнес-модели. Рассматриваются основные подходы к определению термина «уберизация». Делается вывод о том, что процесс уберизации заключается в замене иерархических внутрифирменных отношения на горизонтальные рыночные. Проведен анализ теоретических подходов к определению возможности подобной замены: теории трансакционных издержек, теории асимметрии информации, теории неявных знаний и теории QWERTY-эффектов. Определены факторы эффективности процесса уберизации и его границы.
Регулирование цифровых финансовых активов и применение блокчейн технологий в сельском хозяйстве
Authors: Вартанова Марина Львовна , Дробот Елена Валерьевна
Published: March 2019

Использование цифровых финансовых активов в качестве платежного средства набирает все большую популярность. Токенизация делает сельскохозяйственную отрасль интересной для инвестиций, так как показывает прозрачность процессов, ведь для инвестора главное понимать, куда он вкладывает деньги и что в результате получит. Большинство начальных усилий в блокчейне в сельском хозяйстве – это достижение отслеживаемости. Авторы статьи отмечают, что можно создать эффективную цепь поставок, которая обеспечит обслуживаемость продукта и повысит эффективность сделок. Речь идет об улучшении маржинальности путем снижения бюрократии, поддержки непрерывности решения бизнес-задач через отслеживаемость. При этом блокчейн предоставит всем участвующим сторонам единый источник правдивой информации для сельскохозяйственной логистической цепочки.
Развитие российской экономики в рамках цифровой экосистемы на Евразийском пространстве
Authors: Селезнев Андрей Геннадиевич
Published: March 2019

В данной статье рассматривается вопрос о внедрении инновационных технологий в систему государственного управления экономикой, способствующих эффективному развитию Российской Федерации. Автором предлагается реализовать проект по формированию национальной экосистемы, в рамках которой будут созданы необходимые условия, среда и упрощенные механизмы, позволяющие осуществить прямое и продуктивное взаимодействие между различными участниками экономической деятельности на Евразийском пространстве.
Основным элементом данной экосистемы станет многофункциональный онлайн-ресурс, предоставляющий возможность организовать плодотворное сотрудничество производителям, потребителям, государственным организациям, финансовым структурам, логистическим компаниям и иным экономическим субъектам в едином пространстве экосистемы. Российские представители микро, малого и среднего бизнеса получат выход на зарубежные рынки и доступ к конечному потребителю.
На основе проведенного анализа статистических данных, а также существующей экономической и социальной ситуации в Российской Федерации, автором обоснована актуальность и необходимость реализации предлагаемой инициативы.
Цифровая трансформация в консалтинге
Authors: Лапенков Вячеслав Юрьевич
Published: March 2019

В данной статье представлены основные выводы из эмпирического исследования виртуализации консалтинговых услуг, проведенного при поддержке Ассоциации немецких консультантов в конце 2017 года. В исследовании приняли участие более 500 консультантов. Результаты исследования, с одной стороны, показывают, на каком этапе процесса перехода на цифровые технологии находится отрасль в настоящее время. С другой стороны, результаты показывают каким будет дальнейшее развитие в этой области, какие технологии влияют на него и как внедрение цифровых технологий влияет на бизнес-модель классического консалтинга.
A Canadian Selvage: Weaving Artistic Research into Resource Politics
Authors: Beer Ruth , Chaisson Caitlin
Published: February 2019

This exploratory article addresses our experiences as artist-researchers engaged with “Trading Routes: Grease Trails, Oil Futures,” a research-creation project supported by the Social Sciences and Humanities Research Council of Canada. “Trading Routes” focuses on the intersecting geographies of Indigenous fish grease trails and the proposed Alberta-British Columbia oil pipeline. These converging routes are shedding light on the present entanglement between Indigenous and non-Indigenous cultural heritage, ecological perspectives, and resource extraction. Through artistic scholarship, material production, historical and cultural understanding, we seek to better account for the ways in which an environmental social justice perspective can be crafted into arts-based research. We write from a point of reflection, where we assess, evaluate, disentangle, and unclad some of the learning that has come to us through the research-creation and presentation of contemporary weaving. We suggest that arts-based research can offer a methodology of learning and thinking rooted in a perspective of informing, informality, or thinking about artworks in form, an extension of a/r/tographic praxis that is grounded in an analysis of materiality and aesthetics.
Beadworking as an Indigenous Research Paradigm
Authors: Prete Tiffany Dionne
Published: February 2019

In this article, I outline three principles that form the conceptual basis of an emerging Indigenous research paradigm that I call beadworking. I then relate how beadworking informs my understanding of and engagement with an Indigenous research methodology. Beadworking addresses how Indigenous Peoples’ creation of beadwork can be used to help Indigenous researchers navigate the research process, while being grounded from within an Indigenous worldview. It is my hope that in sharing my research paradigm, it will inspire other Indigenous researchers to define and articulate their own research paradigms through the unique positionality of their own Indigenous People.
Investigation on the effect of endurance training on blood circulating levels of Mir-146a and plasma levels of il-6 in sedentary elderly women
Authors: فلاح فاطمه , رحمانی نیا فرهاد , حجتی ذی دشتی زهرا , شعبانی رامین
Published: February 2019

مقدمه: پدیده سالمندی با التهاب سیستمیک در ارتباط است. miR-146a تنظیم‌کننده منفی حیاتی برای التهاب است و نشان داده شده که سطوح آن با افزایش سن کاهش می یابد. هدف از پژوهش حاضر بررسی تاثیر پیاده‌روی سریع منظم بر سطوح در گردش خون miR-146a و سطوح پلاسمایی اینترلوکین ۶ در زنان سالمند غیرفعال بود.
روش بررسی: در این پژوهش نیمه‌تجربی، ۲۰ زن سالمند (۹/۳±۵/ ۶۳ سال) به طور تصادفی در دو گروه تمرین استقامتی (۱۰ نفر) و شاهد (۱۰ نفر) قرار گرفتند. گروه تمرین سه روز در هفته به مدت دوازده هفته با شدت ۷۵-۷۰ ٪ حداکثر ذخیره ضربان قلب، پیاده‌روی کرد. گروه کنترل در طول دوره مطالعه بدون تمرین باقی ماند. نمونه های خونی قبل و ۷۲ ساعت پس از ۱۲ هفته تمرین، جهت اندازه گیری miR-146a و IL-6 جمع‌آوری شد. پس از تجزیه‌و تحلیل داده ها بر اساس نرمال‌ بودن از آزمون تی‌مستقل، تی‌وابسته، یومن‌ویتنی و ویلکاکسون استفاده شد. بررسی های آماری با استفاده از نرم‌افزارv 16  SPSS انجام گرفت و سطح معنی داری 05/0P≤ در نظر گرفته شد.
نتایج: نتایج نشان داد که در پاسخ به برنامه تمرین استقامتی سطوح miR-146a افزایش 027/0p=) و سطوح IL-6 به طور معنی داری کاهش (۰0۱/۰p=)یافت و این تغییرات با کاهش در شاخص توده بدن (BMI) همراه بود(002/0p=).
نتیجه‌گیری: با توجه به نتایج پژوهش حاضر، پیاده روی سریع می تواند به عنوان یک شکل تمرین موثر در جهت کمک به کاهش عوامل التهابی خون، مورد ملاحظه قرار بگیرد. یافته‌ها هم چنین پیشنهاد می کند miRNA ها، می توانند در پاسخ به پیاده‌روی منظم، در افراد سالمند، بهبود یابند.
Investigate the effect of metformin on some of the behavioral indicators in ovariectomized middle aged mice
Authors: ذاکری مریم , فاطمی ایمان , ذاکری محمدعلی , توکلی محمدالله
Published: February 2019

مقدمه: پیری فرآیندی اجتناب‌ ناپذیر است که باعث افزایش احتمال بیماری و مرگ افراد می‌شود. یائسگی به ‌عنوان بخشی از فرآیند پیری رخ می‌دهد. در این مطالعه اثر متفورمین بر میزان قدرت عضلانی، اضطراب و حافظه در موش‌های سوری ماده اوارکتومی شده بررسی شد.
روش بررسی: در این مطالعه تجربی از 96 سر موش سوری ماده 6 ماهه در محدوده وزنی20 تا 25 گرم استفاده شد. حیوانات به‌طور تصادفی به 6 گروه 16 تایی شامل گروه شم، اوارکتومی شده، اوارکتومی شده درمان با دوز 10 میلی‌گرم بر کیلوگرم متفورمین، اوارکتومی شده درمان با دوز 1 میلی‌گرم بر کیلوگرم متفورمین، گروه متفورمین درمان با دوز 10 میلی‌گرم بر کیلوگرم متفورمین و گروه سالم تقسیم شدند. نخست حیوانات اوارکتومی شدند و سپس به مدت شش ماه با دوزهای 1و10 میلی‌گرم بر کیلوگرم متفورمین درمان شدند. سپس قدرت عضلانی، حافظه و میزان اضطراب در گروه‌های موردمطالعه بررسی شد. آنالیز آماری توسط نرم افزار 16  SPSS V انجام و تفاوت بین گروه‌ها توسط آزمون واریانس یک‌طرفه تحلیل شد.
نتایج: نتایج مطالعه ما نشان داد که متفورمین با دوزهای 1و10 میلی‌گرم بر کیلوگرم در مقایسه با گروه اوارکتومی میزان اضطراب حیوان را به‌طور معنی‌داری کاهش داد (به ترتیب 0024/0p =  و 0295/0p = ) و باعث افزایش حافظه شد (به ترتیب 0044/0 p =) و 0004/0 p =) و دوز 10 میلی‌گرم بر کیلوگرم باعث بهبود  قدرت عضلانی شد (0148/0p = ).
نتیجه‌گیری: متفورمین دارای اثرات مفیدی بر روی اختلالات رفتاری ناشی از پیری و اوارکتومی می‌باشد.