bluuebunny/crossref_metadata_2025 huggingface dataset:
Perfil lipídico em pessoas iniciando a terapia antirretroviral com regimes baseados em efavirenz ou dolutegravir em um centro de referência no Brasil: um estudo de coorte
Authors: Fernandes Ana Cristina da Silva , Cesar Jorgino Júlio , Bonolo Palmira de Fátima , Souza Clessius Ribeiro de , Ceccato Maria das Graças Braga
Published: April 2022

Objetivo: Comparar o impacto no perfil lipídico (PL) em pessoas iniciando a terapia antirretroviral (TARV) baseados pré e pós uso de efavirenz (EFZ) ou dolutegravir (DTG). Métodos:  Coorte prospectiva onde foi estratificados dois grupos, as pessoas vivendo com HIV (PVIV) que iniciaram esquema com DTG ou EFV. A dislipidemia foi definida por critérios laboratoriais no período entre setembro de 2015 a outubro de 2017. Utilizados testes paramétrico e não paramétrico e testes de pares combinados, considerando o p <0,05 estatisticamente significativo. Resultados:  estudados 468 indivíduos estratificados em dois grupos, com (n=180) ou sem (n=288) registros dos exames laboratoriais no tempo T0 (início do tratamento) ou no T48 (12 meses após a dispensação dos antirretrovirais. Entre esses 180, 60 (33,1%) estavam em uso de DTG e 113 (62,4%) em uso de EFZ. Nas comparações do nível sérico (mg/dl) do PL, pré e pós TARV, todos os valores apresentaram aumento e estaticamente significativo para o HDL (p<0,001). Foi analisado a variação do PL, pós TARV e em relação ao uso de EFV e DTG. Em relação ao EFZ, houve aumento do nível sérico de todo o PL, estaticamente significativo para o HDL.  Em relação ao DTG, houve aumento do nível sérico apenas para o VLDL que não foi estaticamente significativo. Conclusão:  comparando o uso do DTG com o EFV, o EFV aumentou o nível sérico do CT e frações, estaticamente significativa para o HDL. Com uso do DTG, houve um aumento do nível sérico de VLDL e diminuição do HDL, sem significância estatística.
Epidemiological profile of gestational and congenital syphilis in the state of Mato Grosso, Brazil
Authors: Martins Luana Sodré , Alessio Junior Luiz Eduardo , Emerick Ludmila Barbosa Bandeira Rodrigues , Emerick Guilherme Luz , Alessio Aline Morandi
Published: April 2022

Introduction: Syphilis is a disease transmitted mainly sexually and vertically. Congenital syphilis is preventable when a pregnant woman is treated, warning about the importance of prenatal screening. Objective: To describe the epidemiological profile of gestational and congenital syphilis in the state of Mato Grosso - Brazil. Methodology: A descriptive cross-sectional study with a quantitative approach, using secondary data from the Notifiable Diseases Information System (SINAN), from 2011 to 2020. Results: 5120 cases of gestational syphilis and 2320 cases of syphilis were reported congenital in the state of Mato Grosso. The induced cases increased over the years, with notification peak of gestational syphilis in the year 2019 with 942 (18%) cases and congenital syphilis in the year of 2018 with 322 (14%) cases. Most women affected by gestational syphilis were young, with low education, mixed race, who underwent prenatal care, did not have their partners treated concomitantly and had a late diagnosis after the first trimester. Patients with congenital syphilis were mostly diagnosed early. Conclusion: The findings change flaws in prenatal care and the need for greater investments in innovative actions in order to reduce vertical transmission of syphilis.
Estágios supervisionados das licenciaturas em ciências biológicas na condição de ensino remoto emergencial: análise de trabalhos acadêmicos no Brasil
Authors: Sudério Fabrício Bonfim , Ribeiro Luís Távora Furtado
Published: April 2022

A condição de Ensino Remoto Emergencial (ERE) durante a pandemia da Covid-19 exigiu um processo de reformulação na sistemática dos estágios supervisionados de cursos de licenciatura. Por isso, o objetivo desta pesquisa foi investigar os impactos da pandemia nos estágios das licenciaturas em ciências biológicas em condição emergencial de aulas remotas. Esse trabalho caracteriza-se como uma pesquisa bibliográfica, exploratória, descritiva, com abordagem qualitativa, envolvendo a categorização dos dados por análise de conteúdo. A investigação envolveu a análise de produções acadêmicas publicadas entre o início dos anos de 2020 e 2022 que buscaram contribuir com as discussões sobre os desafios do ERE nos estágios das licenciaturas em ciências biológicas, tendo o Google Scholar como fonte de pesquisa. O trabalho iniciou com a elaboração de instrumentais de organização das obras, considerando as questões norteadoras relacionadas à pesquisa. Após a seleção de 12 trabalhos, os aspectos positivos e negativos do ERE nos estágios em ciências biológicas foram divididos em 06 e 20 categorias, respectivamente. Os fatores positivos de mais destaques foram: aprendizagem e melhor utilização das ferramentas e recursos tecnológicos no ensino; e reflexão social relacionada à profissão docente. Alguns pontos negativos também se destacaram, como: exclusão digital; falta de preparação adequada dos professores e estudantes para o uso das tec­nologias educacionais; e falta de articulação dos conteúdos teóricos com atividades práticas. De modo geral, os trabalhos revelam a falta de equidade no ensino remoto, mas também apresentam estratégias de superação das dificuldades decorrentes do ERE.
Influência da gestão de resíduos no plano de gerenciamento de obra: um estudo de caso em Teresina – PI
Authors: Leitão Neto Esdras Avelino
Published: April 2022

O setor da construção civil em Teresina encontra-se em crescimento constante, em virtude disso está sendo consumido uma grande quantidade de matéria prima oriunda do meio ambiente, assim como estão sendo gerados grandes quantidades de resíduos. A geração de resíduos provenientes da construção civil (RCC) causam grande preocupação, pois além de ainda ser apresentada como uma das grandes geradoras de impactos ambientais, quando mal executada, sua gestão pode afetar diretamente o desempenho da obra. Este trabalho tem como objetivo analisar o sistema de gestão de resíduos de uma obra, onde por meio de um levantamento das práticas de gestão realizadas, identificar os problemas e fontes geradoras, para então, propor as ações necessárias para a melhoria de sua eficiência. Para essa análise, utilizou-se um checklist estruturado com as fases de gestão no canteiro de obra, com o propósito de colher informações que evidenciem a não adequada ou ausência dessas práticas na obra estudada. Os resultados obtidos demonstram que a falta de fiscalização e conscientização das empresas, afetam diretamente o plano de obra, devido ao fato de que muitas ações ainda são necessárias para uma gestão de resíduos adequada. Assim, com a implantação de um eficiente sistema de gestão, ocorrerá o aumento da organização da obra, redução de custos, além da diminuição do impacto ambiental causado nos canteiros de obras.
Fósseis paleobotânicos no município de Duque Bacelar/MA: levantamento, importância e sensibilização da comunidade acadêmica quanto a sua preservação
Authors: Teixeira Antonia Maria Lima , Brito Marilha Vieira de , Costa Gérson do Nascimento , Rêgo Liliana Corrêa , Menezes Dalila Miranda , Pereira João Clécio Alves , Silva Lilian Rosalina Gomes , Silva Verônica Brito da , Leite Hernando Henrique Batista , Silva Jailson do Nascimento
Published: April 2022

A APA dos Morros Garapenses possui fósseis de pteridófitas e gimnospermas de idade permiana, mas que tem pouco reconhecimento até mesmo da comunidade local e carece de estudos mais aprofundados na área. Neste sentido, o foco dessa pesquisa está em realizar um levantamento dos fósseis vegetais presentes na área supracitada e apresentá-los à comunidade acadêmica, com o objetivo de transmitir conhecimento e sensibilizá-los quanto a importância da preservação. O estudo quali-quantitativo foi desenvolvido no município de Duque Bacelar – MA, onde foi constatada a ocorrência dos fósseis e teve como público alvo acadêmicos de licenciatura em Ciências Biológicas da Universidade Estadual do Maranhão – UEMA, campus Coelho Neto. Como instrumentos de coleta de dados foram utilizados questionários eletrônicos via google forms e visita de campo ao MUHNAP/Museu de História Natural e Ambiental do Vale do Parnaíba, onde estão catalogados alguns espécimes coletados. Analisando a percepção inicial dos alunos acerca dos fósseis vegetais presentes na APA, por meio da aplicação de questionário, foi observado que a maioria não possuía conhecimento dos mesmos, apesar de fazerem parte de sua cidade e região. A respeito disso foram elaborados materiais educativos, (vídeo e cartilha), com informações relevantes sobre o patrimônio presente na região e disponibilizado aos alunos. Os materiais foram divulgados de forma online, via redes sociais, WhatsApp e Instagram. Os resultados foram satisfatórios, os alunos mostraram interesse pelo material e deixaram opinião positiva sobre o mesmo, em um segundo questionário disponibilizado a eles, também de forma online.
A importância da melatonina na síndrome dos ovários policísticos: Uma revisão bibliográfica
Authors: Nascimento Robson Pereira do , Silva Mariana Goes da Souza , Carmo Lívia Benvindo do , Peres Márcia Cristina Terra de Siqueira
Published: April 2022

Introdução: A Síndrome dos Ovários Policísticos (SOP) é caracterizada por uma desordem endócrina múltipla e complexa que cursa com hiperandrogenismo, irregularidade menstrual e pode culminar com infertilidade. Nesta revisão iremos apresentar uma visão geral da SOP, através do resumo da literatura clínica e epidemiológica relativa aos distúrbios dessa síndrome, e realizar a associação dela com a melatonina. Metodologia: Trata-se de um estudo qualitativo descritivo, denominado revisão integrativa da literatura, ela é um instrumento relevante na comunicação dos resultados de pesquisas, facilitando o uso desses resultados na prática clínica, pois proporciona uma síntese do conhecimento já produzido e fornece contribuições para a melhoria da assistência à saúde, através de pesquisas em artigos científicos presentes em bases de dados tradicionais do conhecimento médico: PUBMED/MedLine, Scopus, Embase, Cochranne. Resultados: A Síndrome do ovário policístico acarreta milhares de mulheres no mundo todo, sendo uma desordem muito complexa de ordem endócrina múltipla, ligada ao hiperandrogenismo e desordem menstrual, que pode causar uma série de complicações que levam a infertilidade. A infertilidade é um problema para mulheres que desejam se reproduzir. Descobrir meios de reverter e recuperar as características da reprodução feminina, diminuiria a angústia de milhões de mulheres no mundo. Conclusão: A despeito da influência positiva da melatonina na função reprodutiva, não observamos na literatura estudos randomizados controlados que comparam o seu uso em mulheres com SOP. Mais estudos deverão ser empreendidos nesse intuito. Não há evidências consistentes para o uso sistemático de melatonina em mulheres com SOP ou anovuladoras crônicas.
Team-Teaching-Based Course Scheduling Using Genetic Algorithm
Authors: Sari Rafika , Ramdhania Khairunnisa Fadhilla , Purnomo Rakhmat
Published: April 2022

Scheduling problems occur in various fields, e.g., education, health institutions, transportation, sports, etc. Main scheduling problems in education is course scheduling which creates schedules for students and lecturers. In this study, course scheduling allocates the lecturers in the form of team teaching and courses into the class and a certain time to even out the workload of lecturers per day and a group of students per day in one week without breaking the constraint. The method used in this research is a genetic algorithm where Universitas Bhayangkara Jakarta Raya as the case study. The genetic algorithm process is done by getting several candidate solutions that undergo a process of selection, mutation, and crossing over to produce chromosomes with the best fitness values. The objective function in this research is minimizing the average variance of the workload of lecturers and students per day in one week. The parameters used in genetic algorithm are determined based on the Design of Experiments mechanism (DOE). The optimal parameter values ​​used to run the program are as: population size = 50, with probability of crossing over = 0.4 and probability of mutation = 0.008. The results of scheduling with genetic algorithms show that the value of the workload variance lecturers and students by considering team teaching is better than actual scheduling. The application of the genetic algorithm method results in a decrease in the standard value deviation of the workload of lecturers and a group of students in one week is 0.114 (3.68%) and 3.11 (55.7%). In addition, course scheduling uses a genetic algorithm with consider team teaching better than genetic algorithm without considering team teaching because there is no class schedule that clashes in real conditions.
KECENDERUNGAN VISUALISASI ANAK-ANAK DALAM MERESPON SITUASI PANDEMI
Authors: Bastari Rendy Pandita
Published: April 2022

Abstrak Bahasa visual memiliki efeknya sendiri terhadap audiens. Manifestasi gagasan, ekspresi, ideologi dapat tersalurkan melalui bahasa visual. Hal ini menunjukan bahwa objek visual memiliki makna tertentu, dan terdapat aspek komunikasi yang terkandung di dalamnya. Studi terdahulu menunjukan adanya menifestasi visual pada anak-anak dalam merespon keadaan sosial atau situasi tertentu. Studi ini pun menunjukan bahwa ide yang disampaikan secara visual dapat tercerna dengan baik oleh anak-anak. Studi ini menyimpulkan bahwa proses produksi visual merepresentasikan pengetahuan mereka khususnya secara sosial. Namun studi ini masih belum konklusif terkait kecenderungan karakteristik visualnya. Penelitian ini bermaksud untuk melakukan pendekatan lain dan lebih mengarah pada visualisasinya. Metode yang digunakan adalah analisis visual dari Gillian Rose melalui pengambilan Sampel karya anak-anak dalam merespon situasi pandemi 2020. Sampel berjumlah 18 karya visual dengan kecenderungannya masing-masing. Hasil dari studi ini mendapatkan bahwa anak-anak cenderung merespon dengan visualisasi yang sepenuhnya imajinatif dengan menghadirkan figur-figur dari budaya populer dan ekspresi imajinasinya yang tidak ada konteksnya pada situasi pandemi. Kecenderungan lain terlihat bahwa adanya upaya untuk menggambarkan realita sebagaimana mestinya dan mengandung relevansi terhadap situasi pandemi. Terakhir bahwa terdapat kesan optimisme dalam beberapa karya dan pesimisme dalam beberapa karya. Kata Kunci: anak-anak, karakteristik visual, pandemi, seni AbstractVisual language has its own effect on audiences. The manifestation of ideas, expressions, ideologies can be channeled through visual language.  This shows that visual object has a certain meaning, and there are aspects of communication contained in it. Previous studies have shown visual manifestations in children in response to certain social conditions or situations. This study also proves that visually conveyed idea can be received well by children, this study concludes that visual production process represents their social knowledge. However, this study is inconclusive pertaining their visual characteristic tendencies. This study aims to conduct different approach which is more oriented to their visualization. The method used is visual analysis coined by Gillian Rose through sampling of children's work in response to the 2020 pandemic situation. The Sampel consisted of 18 visual works with their respective tendencies. The results of this study show that children tend to respond with fully imaginative visualizations by presenting figures from popular culture and their imaginary expressions that have no context in a pandemic situation. Another trend appears to be an attempt to portray reality as it should and contain relevance to the pandemic situation. Finally, there is an impression of optimism in some works and pessimism in some works. Keywords: art, children, pandemic, visual characteristic
RANCANG BANGUN APLIKASI MARP UNTUK WAYFINDING GEDUNG DAN RUANGAN DI POLINEMA
Authors: Khairy Muhammad Shulhan , Syalwa Laduni Estu , Nurhasan Usman
Published: April 2022

AbstrakBanyaknya gedung perkuliahan dan kurangnya petunjuk jalan maupun peta lokasi yang mudah diakses membuat lokasi gedung, bangunan, bahkan ruang kelas di Politeknik Negeri Malang (Polinema) mempunyai keterbatasan dalam pencarian. Melihat permasalahan tersebut, maka dibangun sebuah aplikasi pencarian lokasi gedung dan ruangan yang mengacu pada koordinat lokasi yang diperoleh melalui Google Maps. Penelitian ini menggunakan metode Rational Unified Process dengan pendekatan teknologi markerless pada augmented reality sebagai media informasi yang digunakan sebagai penanda gedung dan ruangan yang dapat dijalankan pada smartphone Android. Hasilnya sistem dapat mengimplementasikan metode markerless augmented reality dengan cukup baik yang memperoleh tingkat akurasi 89% dalam ketepatan menampilkan informasi lokasi gedung dan kelas secara real-time pada kamera perangkat android dan dari semua kelas uji. Kata Kunci: android, augmented reality, markerless, wayfinding AbstractThe number of lecture buildings and the lack of street guides and easily accessible location maps make the location of buildings, buildings, even classrooms in Polinema have limitations in the search. This is in accordance with the problems that occur in Polinema's new students in finding the location of each building or class, not least with old students, education personnel, and the public who visit Polinema. Seeing the problem, a search application was built for the location of the building and the room that refers to the coordinates of the location obtained through google map. The study used the Rational Unified Process method with a markerless augmented reality technology as an information medium used as a marker of buildings and rooms that can be run on android smartphones. As a result, the system can implement the Markerless Augmented Reality Method quite well which obtains an 89% accuracy rate in the accuracy of displaying building and class location information in real-time on the cameras of android devices and from all test classes. Keywords: android, augmented reality, markerless, wayfinding
Yaşlı Dostu Kentler ve Topluluklara İlişkin Kuramsal Çerçevelerin Gözden Geçirilmesi
Authors: ÖZGÜR E. Murat , KILINÇ Neriman
Published: April 2022

Nüfus yaşlanması ve kentleşme, birlikte 21. yüzyılı şekillendiren iki önemli küresel demografik eğilimdir. Bu bağlamda kentsel yaşlanma çerçevesi içinde Age-Friendly Cities and Communities(AFCC) olarak adlandırılan girişim gittikçe yaşlılıkta yaşam kalitesini iyileştirmeyi amaçlayan politikaları yönlendiren önemli bir ilgi alanı haline gelmiştir. Bu makale, ilgili alanda son yıllarda hızla geliştirilerek Dünya Sağlık Örgütü girişimine eklenen yeni kavramsallaştırma çabalarını tanıtmak suretiyle ulusal yaşlanma literatürüne katkı sağlamayı amaçlamaktadır. Bu yolla kentleri planlamak ve kent sakinlerine kentsel hizmet sunmakla görevli yerel yönetimlerin ve ilgili paydaşların daha fazla dikkatini çekmenin ve yaşlanma konusunda çalışan sosyal bilimcilerin yerel ampirik araştırmalarına kavramsal bir altlık sağlanmanın mümkün olabileceği düşünülmektedir. Bu anlayışla makalede, AFCC girişimini kavramsallaştırmak için şimdiye kadar geliştirilmiş modeller gözden geçirilmektedir.
Collision of Covid-19 Pandemic Lockdown on the Economic Conditions among Women: A Sociological Perception
Authors: ARA Nelofar , DAS Sukanya
Published: April 2022

The Covid-19 pandemic has had an alarming impact on women globally, with women being disproportionately affected by job loss and burnout as they juggle work with care giving demands. Economic fallout by the Covid-19 pandemic is having a inconsiderate impact on them and they are disproportionately represented in sectors offering low wages, few benefits and the least secure jobs. Women, who are the only bread earners of their families especially widows, have faced an economic failure which later effects other parts of their life as well, such as; in education of their children, nutritious food, health conditions, shelter and in cities usually people used to live on the rent rooms or houses and for those people they have to pay the rent of the house, electricity bills, water connections etc. And it has been found that low-income women, ageing women, and single mothers, around the world and especially from developing countries, encounter the inequalities that exist for women and also the vulnerabilities of belonging to another relatively disadvantaged group of society as well. This paper places the interest on major impacts of Covid-19 pandemic lockdown on different issues and especially on economic toll through which the women are facing many more difficulties to survive. The study is based on reviewing of primary data sources (observations) as well as secondary sources of data. On the basis of the recommendations given in this review based study, the government and non-governmental organizations should look towards these issues that the women are facing since the early days of Covid-19 pandemic.
Increasing the ecological culture of the rural population of Ukraine in conditions of decentralization of power
Authors: Furdychko O. , Nagorniuk O. , Palapa N. , Tarasenko G. , Shcherbliuk A.
Published: April 2022

The village and its nature is the cradle of mankind, maternal comfort, breadwinner, teacher, peace of mind. The article analyzes the current state of the level of ecological culture of the rural population in the conditions of decentralization of power as a factor of balanced development of rural areas. It is emphasized that man, first of all as a biological being, must be aware that the environment is his home, the main means of subsistence. At the same time, awareness of the importance of the quality of human life and wellbeing should be nurtured from early childhood. We can now call the current state of the vast majority of rural areas in Ukraine shameful. All the negative changes of the twentieth century are now gaining momentum in Ukraine. Therefore, the preservation of the environment as a human habitat depends on the quality of education and the pace of formation of the level of environmental awareness and culture in children and youth, their understanding of the fact that they will live tomorrow on planet Earth. On the basis of the analysis of scientific sources the theoretical bases of ecological and social aspects of development of rural territories are considered, the foreign experience of their development is generalized, the tendencies of development of rural territories of Ukraine are outlined. The probability and validity of the obtained results is due to the use of general scientific and special statistical methods. Formation of ecological consciousness is a complex and long-term process. Since ecological consciousness has a corresponding direction, namely: the formation of intellectual and volitional abilities, it from an early age reflects the child's attitude to his life and the environment. Ecological consciousness as a component of mental activity determines the behavior of the individual and that is why it is so important to form it from the period called in the Ukrainian Concept of ecological education «mother school». Today, much attention is paid to the study of the experience of legislative support for local government reform and territorial organization of power of those countries that are political, economic, legal, geographical, demographic, social, cultural and other conditions close to Ukrainian realities. Along with this, the practice of European countries with traditional decentralized systems of balanced rural development deserves special attention. Decentralization has led to complex multilevel governance. Implementing decentralization is a difficult task. Such complex reforms are carried out when there is a clear motivation for them. And it is the high degree of political motivation that is the most important factor in the success of such reforms in Ukraine.
Ecologically safe methods of pest control in modern agricultural technologies
Authors: Fedorenko V. , Mostoviak S. , Mostoviak I.
Published: April 2022

The issue of agricultural crop protection against pests remains constantly relevant. Annual crop losses in the world are 18–20%, estimated at more than 470 billion US dollars because of the harmful effects of arthropods. Most part of the losses of the grown crop occurs under the field conditions before harvest and requires a number of measures to protect plants from pests. The chemical method of plant protection against pests continues to be used by most agricultural producers, which is confirmed by the positive dynamics of the pesticide market development in the world with an annual growth of 2.5–3%. Among the range of chemical plant protection products, sales of insecticides account for 25.3% of world sales. Despite the use of about 3 million tons of pesticides per year, the level of crop losses from harmful entomofauna remains significant. At the same time, deterioration of the phytosanitary condition of agroecosystems caused by a number of abiotic and biotic factors requires a qualitative estimation of the condition and determination of ways of complexes changing of pest organisms in agrobiocenoses and development of new innovative, environmentally safe measures to control their number. Alternative environmentally friendly methods of pest control which meets the principles of integrated plant protection and replacement of chemical insecticides with biological preparations or other environmentally safe methods in modern agrotechnologies for growing crops are increasingly used. This is evidenced by the positive dynamics in the development of the global market for biopesticides with a forecast of annual growth by 14.7%, which may reach $ 8.5 billion US dollars by 2025. 47% of preparations in the range of biopesticides by functional purpose on the world market are preparations against phytophagous insects. Effective control over the pest number in modern agrotechnologies is based on the use of biological control, microbial pesticides, chemical compounds produced by living organisms and can change pest behaviour, secondary metabolites of plants (eg, phenols and polyphenols, terpenoids, alkaloids), on formation of stable plant varieties and plant immunization, etc.
Potensi Beeforage Apis dorsata Binghamii Di KPHP Gularaya Tobimeita Kendari
Authors: Rosmarlinasiah Rosmarlinasiah , Kabe Abigael , Uslinawaty Zakiah , Syamsul Syamsul
Published: April 2022

Abstrak: Penelitian ini bertujuan untuk mengetahui jumlah dan jenis tumbuhan berbunga, waktu berbunga, dan mengetahui tingkat dominansi jenis tumbuhan berbunga yang berpotensi sebagai beeforage bagi lebah Apis dorsata Binghamii. Penelitian dilaksanakan di Hutan Produksi Tobimeita pada bulan Januari hingga Pebruari 2017, dan lokasi penelitian berada dalam KPHP Gula Raya Kendari,.  Metode penelitian menggunakan metode survey, dengan sampel pengamatan menggunakan metode garis berpetak 4 arah mata angin (utara, timur, selatan dan barat ) dan titik pusat pada pohon inang lebah. Data dianalisis menggunakan metode tabulasi dan analisis vegetasi.  Hasil penelitian menunjukkan, terdapat  36 jenis tumbuhan berbunga. Tumbuhan yang berbunga sepanjang waktu adalah Aren (Arenga pinnata) sebagai sumber nektar dan pollen, Kasu Manu-Manu (Malatus peniculatus Muell Arg) sebagai sumber pollen, dan Kelapa (Cocos nucifera) sebagai sumber pollen.  Jenis tumbuhan yang paling dominan (INP) adalah jenis Rambutan Hutan (Nephelium mutabile) sebagai sumber nektar (46,59%), Eha (Castanopsis buruana) sumber nektar dan pollen (34,54%), Puloli (Quercues celebica) sumber pollen (22,89%), Kapuk Randu (Ceiba pentandra) sumber nektar (20,56%), Toho sumber pollen (18,64%), dan Jambu Mete (Anacardium occidentale) sumber nektar (16,61%).  Kata Kunci: Beeforage, Lebah Madu, Apis Dorsata Binghamii, Tumbuhan Berbunga. Abstract: This studi aims to determine the number and species of flowering plants, flowering time, and knowing the level of dominance of flowering plant species which has the potential as bee forage for Apis dorsata Binghamii. The research was carried out in the Production forest of Tobimeita Village, which is within the KPHP Gula Raya Kendari, from January to February 2017. This study used a survey method, the sample of observations using a systematic square gridlines method 4 cardinal directions (north, east, south, west), and the radius center point on the tree where the honeycomb is located. The data were analyzed using tabulation methods and vegetation analysis. The results showed that there were 36 species of flowering plants.  Flowering all the time are sugar palm (Arenga pinnata) a source of nectar an pollen, Kasu Manu-Manu (Malatus peniculatus Muell Arg) a source of pollen, and coconut (Cocos nucifera) as a pollen source.The most dominant plant species (important value index) were forest rambutan (Nephelium mutabile) as a source of nectar (46.59%), eha (Castanopsis buruana) as a source of nectar and pollen (34,54%), Puloli (Quercues celebica) as a source of pollen (22,89%), Kapuk Randu (Ceiba pentandra) as a source of nectar (20,56%), Toho(Artocarpus elasticus) (18,64%) as a source of pollen, and jambu mete (Anacardium occidentale) as a source of nectar (16,61%)  Keywords: Beeforage, Honeybee, Apis Dorsata Binghamii, Flowering Plant
Russia’s Progress in Science and Technology, in the Context of Global Comparisons
Authors: Lapochkina Viktoria , Emelyanova Elena , Shkilyov Ilya
Published: April 2022

Introduction. The purpose of this study is to determine the position of the Russian Federation in international rankings through a comparative analysis of its performance, on the one hand, and the performance of the world’s leading nations, on the other hand. This will facilitate the subsequent development of governance decisions in areas requiring close attention from the state. Methods. We used the following research tools: methods of statistical data grouping and comparative analysis, as well as formal logical methods. Results and Discussion. Since 2014, various factors (foreign policy, economics, the geopolitical situation, volatile prices in the oil market and the instability of the national currency) have been fuelling the crisis in the national economy, which has led to a decrease in Russia’s position in international rankings. After some adaptation to external factors and a partial economic recovery in 2018—2020, Russia’s position has levelled off somewhat, but the pre-crisis results are yet to be achieved. The results of the study have revealed a positive overall trend, with the most significant progress in those rankings that characterise the competitiveness of the national economy. Conclusion. The research results are of practical importance and can be used for adjusting the policy of Russia’s advancement in science and technology.
Comparison of Legal Mechanisms Aimed at Harmonising Policies on Science, Technology and Innovation in Foreign Countries and the Russian Federation
Authors: Dashkova Maria , Vok Milena
Published: April 2022

Introduction.The purpose of this monitoring is to collect, analyse, and subsequently compare the legal mechanisms aimed at harmonising policies on science, technology and innovation in foreign countries and the Russian Federation. The study focuses on the mechanisms of harmonising government policies on science, technology and innovation that are applied abroad (specifically in India, Norway, Switzerland and Australia) and in the Russian Federation.Monitoring Tools.The study employs general scientific methods (analytical, systematic, functional) and specific scientific methods (the formal legal method, interpretation of legal rules).Results.The materials collected while preparing this paper paint a picture of the tools that are used around the world (in countries like India, Norway, Switzerland and Australia in particular) to harmonise government policies on science, technology and innovation. Looking at each of the countries listed, we examine the essential legal and regulatory documents, including strategic programme documents, used as basis for making decisions on taking specific measures in the field, as well as the powers of the relevant competent bodies. We also analyse similar regulations and mechanisms that exist in the Russian Federation.Conclusion.Our study results in determining the most successful examples of foreign mechanisms aimed at harmonising government policies on science, technology and innovation, which can be potentially borrowed in the Russian Federation. These insights can be used by lawyers and research associates as part of their professional and scientific activities in the field of legislation on science, technology and innovation.
Publication Activity Trends among Russian Researchers in 2016–2020, Based on International Scientific Citation Databases: Web of Science Core Collection and Scopus
Authors: Borodik Karina , Dikusar Konstantin , Bogatov Viktor
Published: April 2022

Introduction.TheimprovementofRussianresearchers’standingin the global academic space, including the improvement of publication activity indicators, will allow for a better representation of Russia’s scientific achievements. For this reason, this paper presents the results of monitoring the publication activity of Russian researchers, aiming to detect the development trends in Russian science through a comparison of different aspects.MonitoringTools.We monitored the data on the number of articles published by researchers in the Web of Science Core Collection and the Scopus database, comparing our findings across countries and grouping them by STAS priorities, by region (within Russia) and by higher education institution (within Russia). We used themethodsofcomparativeanalysis,groupingsandrankings.Our calculations were based on statistical and mathematical methods. Results.We arrive at a conclusion that the demand for Russian research in the academic community is increasing and that Russia is consolidating its position in the international publication arena, as evidenced by the positive growth dynamics in the number of research articles published inRussia,accordingtotheWebofScienceCoreCollectionand Scopus.Conclusion.The number of articles by Russian researchers (both in general and in the fields prioritised by Russia’s Scientific and Technological Advancement Strategy) continues to increase. At the same time, international citation databases reveal a decrease in the share of articles by Russian researchers in the global publication flow in 2020. One of the reasons behind this trend are the complications caused around the world by the pandemic. The monitoring results can be used for developing a methodology for assessing research activity performance.
Board Meeting Federal Service for Intellectual Property (Rospatent) (December 14, 2021)
Authors: Gorushkina Svetlana
Published: April 2022

The publication is devoted to a meeting of the Board of the Federal Service for Intellectual Property, which addressed issues related to the digital transformation of the department aimed at increasing the satisfaction of citizens and organizations with the quality of public services in the field of intellectual property by transferring human interaction with the state to a digital environment. The participants of the meeting also discussed the issue 'On the International Competence Center in the field of Intellectual Property as a national interactive platform', which is being created on the basis of the RGAIS and the work plan of the Board of Rospatent for 2022.
Youngstock Management as “The Key for Everything”? Perceived Value of Calves and the Role of Calf Performance Monitoring and Advice on Dairy Farms
Authors: Palczynski Laura J. , Bleach Emma C. L. , Brennan Marnie L. , Robinson Philip A.
Published: April 2022

Replacement heifers are key to the future milking herd and farm economic efficiency but are not always prioritised on dairy farms. Dairy enterprises are comprised of components which compete for limited resources; scarce information about calf performance and the associated losses and (potential) gains on farms can mean calves are prioritised less in management and investment decisions. The research reported in this paper explored the personal and contextual factors that influence calf management decisions on dairy farms. Forty in-depth, semi-structured interviews were conducted with dairy farmers (26 interviews) and farm advisors (14 interviews) who were recruited using purposive and “snowball” sampling. Interviews were recorded, transcribed, and thematically analysed. Six major themes were constructed from the interview data relating to: the perceived importance of youngstock management, the role and influence of calf rearers, calf performance monitoring, farmer engagement with information and advice, the quality of communication and advice, and veterinary involvement in calf rearing. Results indicated that although the wider dairy industry has promoted the importance of youngstock, calves often have not been fully integrated into the whole dairy farm system, nor culturally accepted as an integral part of the productive herd. Calves tended to be marginalised on farms, largely due to limited resources, lack of data monitoring, and their unrecognised potential, as well as social norms and scarcity of support structures impacting upon farm investment and management decisions. Many calf rearers were disappointed by the repetition and impractical nature of information in print media. Most farmers did not routinely consult their veterinarian about their calves, rather following a reactive treatment model even when a preventive herd health strategy was applied to the adult herd. Advisory structures often require a driven individual with calf-centric interest to prevent calves from being overlooked. Furthermore, advisory efforts often failed to motivate farmers to act on advice. These findings indicate the need for greater focus on how to achieve rearing targets by provision of technical and support structures to foster action toward improved calf wellbeing, and for the status of calves to be raised in line with their vital importance for the future dairy herd.
Adopting the Local Knowledge of Coastal Communities for Climate Change Adaptation: A Case Study From Bangladesh
Authors: Sultana Nahid , Luetz Johannes M.
Published: April 2022

Bangladesh has a unique coastal system with both proximity of climatic vulnerability and opportunity, having rich coastal resources. The upkeep of people's livelihoods in the coastal zone largely depends on the degree to which key stakeholders at all levels of decision-making can participate in climate adaptation planning and implementation processes. These facts are well recognized in Bangladesh's Integrated Coastal Zone Management Plan (ICZM), National Adaptation Program of Action (NAPA), and the Bangladesh Climate Change Strategy and Action Plan (BCCSAP), which emphasize the need for integrated multi-level decision-making at all stages of the adaptive management cycle. The aim of this article is to assess the value of coastal community engagement in Bhola and Satkhira districts of Bangladesh and highlight priority programs that may increase adaptive capacity in the face of climate change. To this end, interviews were conducted involving local farmers, fishers, women householders, businessmen, and other local leaders, thus yielding a total 240 participants who informed this empirical research. Case studies of villages of these districts highlight helpful examples of adaptation initiatives that may increase people's capacity to respond to the adverse effects of climate change, both autonomously as villagers, and as part of a coordinated program to reduce vulnerability. Issues flagged for urgent attention include water management, socioeconomic conditions, and migration away from coastal districts. The findings point to both potential interventions and a need to better prioritize adaptation options and strategies that are suitable for local contexts. In some cases, these options reflect existing Indigenous and local knowledge (ILK) and adaptation practices which may be both supported and leveraged through the coordinated implementation of different aspects of government policies.
Predictors of Maternal Death Among Women With Pulmonary Hypertension in China From 2012 to 2020: A Retrospective Single-Center Study
Authors: Dai Ling-Ling , Jiang Tian-Ci , Li Peng-Fei , Shao Hua , Wang Xi , Wang Yu , Jia Liu-Qun , Liu Meng , An Lin , Jing Xiao-Gang , Cheng Zhe
Published: April 2022

Background

Previous studies have suggested that pregnant women with pulmonary hypertension (PH) have high maternal mortality. However, indexes or factors that can predict maternal death are lacking.

Methods

We retrospectively reviewed pregnant women with PH admitted for delivery from 2012 to 2020 and followed them for over 6 months. The patients were divided into two groups according to 10-day survival status after delivery. Predictive models and predictors for maternal death were identified using four machine learning algorithms: naïve Bayes, random forest, gradient boosting decision tree (GBDT), and support vector machine.

Results

A total of 299 patients were included. The most frequent PH classifications were Group 1 PH (73.9%) and Group 2 PH (23.7%). The mortality within 10 days after delivery was 9.4% and higher in Group 1 PH than in the other PH groups (11.7 vs. 2.6%, P = 0.016). We identified 17 predictors, each with a P-value < 0.05 by univariable analysis, that were associated with an increased risk of death, and the most notable were pulmonary artery systolic pressure (PASP), platelet count, red cell distribution width, N-terminal brain natriuretic peptide (NT-proBNP), and albumin (all P < 0.01). Four prediction models were established using the candidate variables, and the GBDT model showed the best performance (F1-score = 66.7%, area under the curve = 0.93). Feature importance showed that the three most important predictors were NT-proBNP, PASP, and albumin.

Conclusion

Mortality remained high, particularly in Group 1 PH. Our study shows that NT-proBNP, PASP, and albumin are the most important predictors of maternal death in the GBDT model. These findings may help clinicians provide better advice regarding fertility for women with PH.
Cardiac Remodeling in Heart Failure: Role of Pyroptosis and Its Therapeutic Implications
Authors: Chai Ruoning , Xue Wenjing , Shi Shuqing , Zhou Yu , Du Yihang , Li Yuan , Song Qingqiao , Wu Huaqin , Hu Yuanhui
Published: April 2022

Pyroptosis is a kind of programmed cell death closely related to inflammation. The pathways that mediate pyroptosis can be divided into the Caspase-1-dependent canonical pathway and the Caspase4/5/11-dependent non-canonical pathway. The most significant difference from other cell death is that pyroptosis rapidly causes rupture of the plasma membrane, cell expansion, dissolution and rupture of the cell membrane, the release of cell contents and a large number of inflammatory factors, and send pro-inflammatory signals to adjacent cells, recruit inflammatory cells and induce inflammatory responses. Cardiac remodeling is the basic mechanism of heart failure (HF) and the core of pathophysiological research on the underlying mechanism. A large number of studies have shown that pyroptosis can cause cardiac fibrosis, cardiac hypertrophy, cardiomyocytes death, myocardial dysfunction, excessive inflammation, and cardiac remodeling. Therefore, targeting pyroptosis has a good prospect in improving cardiac remodeling in HF. In this review, the basic molecular mechanism of pyroptosis is summarized, the relationship between pyroptosis and cardiac remodeling in HF is analyzed in-depth, and the potential therapy of targeting pyroptosis to improve adverse cardiac remodeling in HF is discussed, providing some ideas for improving the study of adverse cardiac remodeling in HF.
Radiosurgery in Treatment of Ventricular Tachycardia – Initial Experience Within the Polish SMART-VT Trial
Authors: Kurzelowski Radosław , Latusek Tomasz , Miszczyk Marcin , Jadczyk Tomasz , Bednarek Jacek , Sajdok Mateusz , Gołba Krzysztof S. , Wojakowski Wojciech , Wita Krystian , Gardas Rafał , Dolla Łukasz , Bekman Adam , Grza̧dziel Aleksandra , Blamek Sławomir
Published: April 2022

Background

Stereotactic Arrhythmia Radioablation (STAR) is an emerging treatment modality for patients with sustained ventricular tachycardia (VT) and refractory to treatment with drugs and radiofrequency catheter ablation (RFA). It is believed that up to 12–17% of patients experience recurrence of VT within 1 year of follow-up; thus, novel therapeutic options are needed. The aim of this article is to present initial experience within a novel treatment modality for VT.

Case Summary

Two patients with a medical history of coronary artery disease and heart failure with reduced left ventricle (LV) ejection fraction, after implantation of cardioverter-defibrillator (ICD) and previous unsuccessful RFAs owing to sustained VT were admitted to the cardiology department due to recurrence of sustained VT episodes. With electroanatomical mapping (EAM), the VT substrate in LV has been confirmed and specified. In order to determine the target volume for radioablation, contrast-enhanced computed tomography was performed and the arrhythmia substrate was contoured using EAM data. Using the Volumetric Modulated Arc Therapy technique and three 6 MeV flattening filter-free photon beam fields, a single dose of 25 Gy was delivered to the target volume structure located in the apex and anterior apical segments of LV in the first patient and in the apex, anterolateral and inferior apical segments of the second patient. In both cases, volumes of the target structures were comparable. Interrogation of the implanted ICD at follow-up visits throughout 6 months after the treatment revealed no VT episodes in the first patient and sudden periprocedural increase in VT burden with a subsequent gradual decrease of ventricular arrhythmia to only two non-sustained episodes at the end of the follow-up period in case of the second patient. A significant reduction in premature ventricular contractions burden was observed compared to the pre-treatment period. No noticeable deterioration in LV function was noted, nor any adverse effects of radiosurgery associated with the implanted device.

Conclusion

The early response to STAR can be unpredictable and probably does not reflect the final outcome of irradiation. Close monitoring of patients, especially in the early period after irradiation is crucial to properly handle potentially harmful early reactions to STAR.
Healthcare Utilization and Medical Cost of Gastrointestinal Reflux Disease in Non-tuberculous Mycobacterial Pulmonary Disease: A Population-Based Study, South Korea, 2009–2017
Authors: Kim Taehee , Yoon Jai Hoon , Yang Bumhee , Ryu Jiin , Yoon Chang Ki , Kim Youlim , Sohn Jang Won , Lee Hyun , Choi Hayoung
Published: April 2022

Gastroesophageal reflux disease (GERD) is a common non-respiratory comorbidity in patients with non-tuberculous mycobacterial pulmonary disease (NTM-PD). However, little is known about the association between GERD and healthcare utilization and medical costs of NTM-PD. Thus, we evaluated this association using the Health Insurance Review and Assessment Service National Patient Sample. NTM-PD patients with GERD had significantly higher healthcare use and spent a higher total on medical costs (5,098 vs. 2,675 USD/person/year) than those without GERD (P <0.001 for all). Therefore, an appropriate management of GERD in NTM-PD patients can be an important factor to reduce the disease burden.