bluuebunny/crossref_metadata_2025 huggingface dataset:
Shallow-Water Benthic Communities on Soft Bottoms of a Sub-Arctic Fjord (Southern Barents Sea, Russia) along a Gradient of Ecological Factors
Authors: Pavlova Lyudmila V. , Zuyev Yury A. , Dvoretsky Alexander G.
Published: January 2023

Kola Bay is the most developed coastal area in the Russian part of the Barents Sea, but despite a long history of research, information about the local shallow-water benthic communities is lacking. For this reason, in this fjord area, we investigated the soft-bottom zoobenthos to determine its distribution and the factors influencing its abundance, biomass, and diversity. An analysis of 24 samples collected by divers at eight stations located at 7–8 and 10–15 m depths revealed 127 benthic taxa with an average abundance and biomass of 12,190 ± 4740 ind. m−2 and 30 ± 8 g m−2, respectively. The most severe abiotic conditions (high rates of sedimentation and eutrophication) were found at the head of the bay while the highest densities of predator red king crabs were registered in the middle part. The total benthic abundance and biomass, as well as the abundances of infauna, mobile taxa, subsurface deposit feeders, and surface deposit feeders, decreased towards the central part of the bay, reflecting gradients in the environmental conditions. In the inner part of the bay, we registered two communities: Cossura pygodactylata + Ciliatocardium ciliatum and Arctica islandica + Laonice cirrata, while the benthos of the middle part was less structured. Redundancy analysis indicated that the faunal abundances were influenced mainly by predator density (negative association) and the organic matter content (positive association). The total benthic biomass was negatively linked to water temperature due to the predominance of cold-water species in the area and a close positive association of this factor with crab abundance. In contrast, the highest diversity was registered at the warmer sites, which may have been a reflection of the borealization process in the Arctic. Our results contribute towards the proper management and conservation of the local benthic ecosystem and provide reference data for future monitoring programs and coastal management guidelines.
RT-LAMP Multicenter Study for SARS-CoV-2 Genome Molecular Detection in Brazilian Swab and Saliva Samples
Authors: da Costa Vanessa Duarte , Santos Alanna Calheiros , da Silva Lucas Lima , Wiggers Wilian Jean , Ivantes Claudia Alexandra Pontes , Lima Danielle Malta , Colares Jeová Keny Baima , Dallacqua Deusilene Souza Vieira , Motta-Castro Ana Rita Coimbra , Dávila Alberto Martín Rivera , Teles Sheila Araujo , Carneiro Megmar Aparecida dos Santos , Caetano Karlla Antonieta Amorim , Anunciação Fernando Antonio Costa , de Paula Vanessa Salete , Villar Livia Melo ,   on behalf of The Brazilian COVID-19 Research Group
Published: January 2023

Reverse transcription loop-mediated isothermal amplification (RT-LAMP) is a rapid method that can replace RT-qPCR. A simple molecular assay for SARS-CoV-2 RNA detection in gold-standard diagnosis through swabs and alternative specimens such as saliva could be helpful in promoting genomic surveillance. A multicenter study was conducted to evaluate the RT-LAMP assay method as an alternative for the molecular detection of SARS-CoV-2 lineages in swab and saliva samples. A total of 350 swabs from individuals with (n = 276) or without (n = 74) COVID-19 tested by RT-qPCR were collected. Paired saliva was also collected from 90 individuals who had SARS-CoV-2 RNA that was detectable (n = 30) or undetectable (n = 60) via RT-qPCR. For the RT-LAMP methodology, six primers were used for ORF1 gene amplification. As for SARS-CoV-2 genotyping, 39 swabs had the whole genome sequenced by MinION. The sensitivity of RT-LAMP to the swab was 90.2%. For the swab samples with Ct ≤ 30, the sensitivity improved by 96%. Considering saliva with Ct ≤ 30 in RT-qPCR testing, the RT-LAMP sensitivity was 100%. The RT-LAMP specificity was 100% for both the swab and saliva samples. This RT-LAMP assay was capable of detecting all the SARS-CoV-2 lineages circulating in the Brazilian swab samples. The RT-LAMP method has significant potential for use in clinical routines since it was capable of detecting SARS-CoV-2 RNA in swab and saliva samples.
A Similarity Measure-Based Approach Using RS-fMRI Data for Autism Spectrum Disorder Diagnosis
Authors: Zhang Xiangfei , Shams Shayel Parvez , Yu Hang , Wang Zhengxia , Zhang Qingchen
Published: January 2023

Autism spectrum disorder (ASD) is a lifelong neurological disease, which seriously reduces the patients’ life quality. Generally, an early diagnosis is beneficial to improve ASD children’s life quality. Current methods based on samples from multiple sites for ASD diagnosis perform poorly in generalization due to the heterogeneity of the data from multiple sites. To address this problem, this paper presents a similarity measure-based approach for ASD diagnosis. Specifically, the few-shot learning strategy is used to measure potential similarities in the RS-fMRI data distributions, and, furthermore, a similarity function for samples from multiple sites is trained to enhance the generalization. On the ABIDE database, the presented approach is compared to some representative methods, such as SVM and random forest, in terms of accuracy, precision, and F1 score. The experimental results show that the experimental indicators of the proposed method are better than those of the comparison methods to varying degrees. For example, the accuracy on the TRINITY site is more than 5% higher than that of the comparison method, which clearly proves that the presented approach achieves a better generalization performance than the compared methods.
Protocol of Breast Cancer Prevention Model with Addition of Breast Ultrasound to Routine Gynecological Visits as a Chance for an Early Diagnosis and Treatment in 25 to 49-Year-Old Polish Females
Authors: Śniadecki Marcin , Jaworek Paulina , Chmielewska Zuzanna , Poniewierza Patryk , Stasiak Maria , Danielkiewicz Martyna , Stencelewski Damian , Brzeziński Michał , Boyke Zuzanna Anna , Wycinka Ewa , Sunil Medha , Nguyen Marie , Klasa-Mazurkiewicz Dagmara , Koziełek Krzysztof , Rak Piotr , Wolny Yvonne , Liro Marcin , Guzik Paweł Władysław , Dobruch-Sobczak Katarzyna , Wydra Dariusz
Published: January 2023

The low attendance rate for cancer screening tests in Poland is a major healthcare concern that requires specific analysis and the development of implementation recommendations for prevention, and both actions are likely to benefit culturally similar countries. Four female cancers account for approximately 20% of all cancer cases—breast cancer, cervical cancer, endometrial cancer, and ovarian cancer—suggesting that gynecologists have a significant preventative role. Of the four, breast cancer and cervical cancer are among the 10 most common malignant neoplasms globally, regardless of gender, occur only in women and are known to have effective screening measures. Our research aims to create a screening model that combines cervical cancer and breast cancer to maximize health outcomes for women at risk of both cancers. In the study protocol, we have created a model that maximizes benefits for patients with minimal additional costs to the health care system. To achieve the set goal, instead of regular clinical breast exams as recommended by the gynecological societies, we proposed an ultrasound examination, during which palpation may also be performed (in the absence of elastography). We present a scheme for such a protocol that takes into consideration all types of prevention in both cancers, and that emphasizes breast ultrasound as the most frequently missing element. Our study includes a discussion of the strengths and weaknesses of our strategy, and the crucial need for infrastructure and education for the successful implementation of the program. We conclude that our model merits consideration and discussion among health-care decision makers, as the screening changes we propose have significant potential benefits for the female population.
Usefulness of Chromogenic Media with Fluconazole Supplementation for Presumptive Identification of Candida auris
Authors: Ruiz-Gaitán Alba , Sigona-Giangreco Ignacio , Pérez-Royo José Manuel , Garcia-Bustos Victor , García-Hita Marta , Valentín-Gómez Eulogio , Almaraz Salvador Giner , de Groot Piet W. J. , Pemán Javier
Published: January 2023

Introduction:Candida auris is a major threat to public health. Rapid detection is essential for early treatment and transmission control. The use of chromogenic media allows the presumptive identification of this new species. The aim of this study is to describe the morphological characteristics of C. auris colonies on three commercial chromogenic media. Methods: Nineteen C. auris isolates from different countries/clades and 18 isolates of other species were cultivated in CHROMagarTM Candida Plus, HiCromeTM Candida, CHROMagar-Candida, and fluconazole-supplemented (32 mg/L) CHROMagar-Candida media. Results: On CHROMagarTM Candida Plus and HiCromeTM Candida, C. auris isolates from Colombia, Venezuela, India, Korea, and Japan displayed blue-shaded colonies, while isolates from Spain and Germany exhibited light pink shades with a bluish halo. All isolates showed white to pink colonies on CHROMagar-Candida. On CHROMagar Candida supplemented with fluconazole, whilst C. auris, C. glabrata, or C. krusei showed a similar pink color at 48 h incubation, phenotypic differentiation was possible by the rough, paraffin-like texture or the intense purple color acquired by C. krusei and C. glabrata, respectively. Moreover, in this medium, the presence of C. auris in combination with other species of similar color was not limiting for its early identification, due to this medium selecting only strains resistant to this antifungal. Conclusions: The use of chromogenic media such as CHROMagarTM Candida Plus facilitates a presumptive identification of C. auris. However, this identification can be difficult in the presence of mixed cultures. In these cases, the use of CHROMagarTM Candida medium with 32 mg/L fluconazole offers better performance for the identification of C. auris by inhibiting fluconazole-susceptible strains and selecting rare or high fluconazole MIC (>32 mg/L) isolates.
Diagnosis of Cholangiocarcinoma
Authors: Shin Dong Woo , Moon Sung-Hoon , Kim Jong Hyeok
Published: January 2023

Cholangiocarcinoma (CCA), a tumor of the bile duct epithelium, is increasing in incidence. CCA remains a highly fatal malignancy because early diagnosis is difficult. Based on its anatomical location, CCA can be categorized into the following three groups: perihilar, intrahepatic, and extrahepatic. Patients with CCA complain of asymptomatic jaundice, weight loss, and right upper quadrant abdominal discomfort. Imaging modalities, including transabdominal ultrasound, computed tomography, and magnetic resonance imaging, play an important role in detecting tumors as well as guiding biopsy procedures and staging workups in CCA. Characteristically, extrahepatic CCA shows abrupt changes in ductal diameter with upstream ductal dilation. Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) are recommended as the next step in the evaluation of extrahepatic CCA. Tissue is obtained through EUS-FNA or ERCP (biopsy, brush cytology), and therapeutic intervention (such as stent insertion) is performed with ERCP. Moreover, several serum tumor markers (carbohydrate antigen 19-9 and carcinoembryonic antigen) can be useful in diagnosing CCA in some patients.
Changes in Macular Thickness after Cataract Surgery in Patients with Open Angle Glaucoma
Authors: Pakuliene Giedre , Rylskyte Neda , Kuzmiene Loreta , Siesky Brent , Verticchio Alice , Harris Alon , Januleviciene Ingrida
Published: January 2023

Background: The purpose of this study was to examine the changes in IOP, total macular and RNFL, ganglion cell layer (GCL) thickness, and aqueous humour flare in open angle glaucoma (OAG) patients before and 6 months after cataract surgery. Methods: This was a prospective observational case–control age- and gender-matched study. Groups: 40 subjects in a controlled OAG (OAGc) group, 20 subjects in an uncontrolled OAG (OAGu) group, and 60 control group subjects. Examination: complete ophthalmic evaluation, IOP measurement, anterior and posterior segment Optical Coherence Tomography (OCT), and laser flare photometry before and 6 months postoperatively. Results: Six months postoperatively IOP decreased in all groups. An increase in macular thickness was found postoperatively in all groups. Preoperative aqueous humour flare was higher in the OAGc group than in the control group. After cataract surgery, aqueous humour flare was higher in the control group compared to the preoperative result. Conclusions: Changes in IOP following cataract surgery were strongly negatively correlated with preoperative IOP. An increase in macular thickness was observed 6 months postoperatively in all groups. Aqueous humour flare did not differ in OAGc and OAGu groups pre- and postoperatively but significantly increased in the control group postoperatively.
DeepSmile: Anomaly Detection Software for Facial Movement Assessment
Authors: Rodríguez Martínez Eder A. , Polezhaeva Olga , Marcellin Félix , Colin Émilien , Boyaval Lisa , Sarhan François-Régis , Dakpé Stéphanie
Published: January 2023

Facial movements are crucial for human interaction because they provide relevant information on verbal and non-verbal communication and social interactions. From a clinical point of view, the analysis of facial movements is important for diagnosis, follow-up, drug therapy, and surgical treatment. Current methods of assessing facial palsy are either (i) objective but inaccurate, (ii) subjective and, thus, depending on the clinician’s level of experience, or (iii) based on static data. To address the aforementioned problems, we implemented a deep learning algorithm to assess facial movements during smiling. Such a model was trained on a dataset that contains healthy smiles only following an anomaly detection strategy. Generally speaking, the degree of anomaly is computed by comparing the model’s suggested healthy smile with the person’s actual smile. The experimentation showed that the model successfully computed a high degree of anomaly when assessing the patients’ smiles. Furthermore, a graphical user interface was developed to test its practical usage in a clinical routine. In conclusion, we present a deep learning model, implemented on open-source software, designed to help clinicians to assess facial movements.
Civilian UAV Deployment Framework in Qatar
Authors: AL-Dosari Khalifa , Hunaiti Ziad , Balachandran Wamadeva
Published: January 2023

Drone deployment in Qatar has been lagging behind that in other countries due to a wide range of reported challenges. This study developed a framework to address these operational gaps and serve as a roadmap for different stakeholders to enable drone applications for successful, safe, accountable and sustainable development. Moreover, the framework could help overcome key challenges and lay the groundwork for addressing other challenges facing UAV deployment in Qatar, thereby enabling Qatar to join the global efforts in this technological evolution. The framework was based on an analysis of the available data from previous guidelines for UAV operation and the identification of the challenges facing drone deployment in Qatar. The proposed framework was evaluated through interviews with key stakeholders in the Qatari drone steering committee. The outcomes from this evaluation supported the implementation of the framework with minor amendments and are ready to be put into practice by policymakers. In addition, it could be helpful for Gulf Cooperation Council (GCC) countries and other countries in the region to consider this framework in their efforts to facilitate drone deployment.
A New Improvement Proposal to Estimate Regional Input–Output Structure Using the 2D-LQ Approach
Authors: Martínez-Alpañez Rubén , Buendía-Azorín José Daniel , Sánchez-de-la-Vega María del Mar
Published: January 2023

The use of location quotients for the estimation of regional input–output tables has been found to be a useful and efficient tool to estimate intraregional production coefficients and multipliers. This paper considers some regionalisation methodologies based on location quotients for the estimation of input–output tables—some of which have hitherto not been analysed at the regional level—and studies which one provides the best estimation (best goodness of fit). We focus the analysis mainly on the accuracy of Flegg’s location quotient (FLQ) and two-dimensional location quotient (2D-LQ). The analysis makes use of the multiregional input–output table for Korea for the year 2015 to evaluate the accuracy of the 2D-LQ method against FLQ. A novel proposal for the determination of the parameters corresponding to the 2D-LQ method is presented. This proposal is evaluated in Korean regions and is also applied to Spanish regions. The results obtained from the research conclude the general superiority of the 2D-LQ method, thus corroborating the results of other studies at the national level as well as the validity of our proposal.
Warm Starting Variational Quantum Algorithms with Near Clifford Circuits
Authors: Niu Yun-Fei , Zhang Shuo , Bao Wan-Su
Published: January 2023

As a mainstream approach in the quantum machine learning field, variational quantum algorithms (VQAs) are frequently mentioned among the most promising applications for quantum computing. However, VQAs suffer from inefficient training methods. Here, we propose a pretraining strategy named near Clifford circuits warm start (NCC-WS) to find the initialization for parameterized quantum circuits (PQCs) in VQAs. We explored the expressibility of NCCs and the correlation between the expressibility and acceleration. The achieved results suggest that NCC-WS can find the correct initialization for the training of VQAs to achieve acceleration.
A Semi-Octagonal 40-Bit High Capacity Chipless RFID Tag for Future Product Identification
Authors: Haider Usman A. , Noman Muhammad , Rashid Aamir , Rmili Hatem , Ullah Hidayat , Tahir Farooq A.
Published: January 2023

This paper presents a unique geometry of a chipless radio frequency identification (RFID) tag for encoding a large number of bits in a very small form factor. The tag geometry consists of semi-octagonal copper strips, sequentially laid on a single side of an ultra-thin substrate. A unique and robust encoding mechanism for the tag identification (ID) is proposed. The operating frequency spectrum of the tag ranges from 3.1 to 10.5 GHz. The tag is compact, having an overall size of 14.5 × 28 mm2. The proposed tag exhibits very high code density of 9.85 bits/cm2 and spectral efficiency of 5.4 bits/GHz. The unique geometric configuration of the proposed tag allows it to encode up to 40 bits of data as an RCS signature. This chipless RFID tag seems to be a potential candidate for a wide range of modern RFID applications.
Variations in Ecosystem Service Value and Its Driving Factors in the Nanjing Metropolitan Area of China
Authors: Chen Shulin , Liu Xiaotong , Yang Li , Zhu Zhenghao
Published: January 2023

More than 60% of the world’s ecosystem services have deteriorated over the past few decades. Studying the spatio-temporal fluctuations in ecosystem service value and its influencing factors is important for identifying regional ecosystem service value issues, upholding regional ecological harmony, and encouraging regionally healthy and coordinated sustainable development. Ecosystem service value has so far been studied primarily in relation to the effect of socioeconomic and physical–geographical variables. However, the trade-offs and synergies among ecosystem service values also drive the spatio-temporal variations in ecosystem service value. Few studies have been conducted to date to investigate the trade-offs and synergies between ecosystem service values and their impact on ecosystem service value. Therefore, this paper used sensitivity analysis, correlation analysis, trade-offs and synergies analysis, and a Geodetector to examine changes in ecosystem service value and their influencing factors within the Nanjing metropolitan region. The ecosystem service value decreased somewhat overall between 2000 and 2020, with a decline rate of 2.19 million CNY/year. In comparison to the north of the Nanjing metropolitan region, the ecosystem service value was relatively higher in the south. The water bodies had the highest total ecosystem service value, followed by forest land, cultivated land, and grassland, with construction land and unused land having the lowest ecosystem service values overall. The main socioeconomic factor influencing the spatial variations in ecosystem service value was population density, while the main physical–geographical factors were the digital elevation model, the normalized difference vegetation index, and precipitation. As a result, the Nanjing metropolitan area should tighten its grip on excessive population growth. In contrast to the expository strength of a single factor on the ecosystem service value, the influence of all individual elements on the ecosystem service value under interaction was significantly increased, and the interaction among the normalized difference vegetation index and gross economic product had the most obvious effect on the ecosystem service value. The spatial variation in the ecosystem service value was also influenced by trade-offs and synergies between the value of supply services, regulation services, support services, and cultural services. Therefore, trade-offs and synergies among ecosystem services also need to be considered in land-use decisions.
A Comparative Analysis of Polyphenol Content and Biological Potential of Quercus petraea Matt. and Q. pubescens Willd. Bark Extracts
Authors: Nisca Adrian , Ștefănescu Ruxandra , Mocan Andrei , Babotă Mihai , Nicolescu Alexandru , Mare Anca Delia , Ciurea Cristina Nicoleta , Man Adrian , Tanase Corneliu
Published: January 2023

Quercus wood (oak wood) is a valuable resource, which has led to the intense processing of oak trees by the forestry industry. As a result, large amounts of forestry by-products (bark and leaves) are left in the woods, considered valueless. Thus, the aim of this study was to evaluate and compare the phytochemical profile and potential biological activities of Q. petreaea Matt. and Q. pubescens Willd. bark extracts. The extracts were obtained by microwave (MAE) and ultrasound-assisted extraction (UAE) with water (100%) and ethanol:water (70:30). These extracts were then characterized in terms of the total polyphenolic and tannin contents using the Folin–Ciocâlteu method. Their antioxidant properties were determined by observing the neutralizing effects of the extracts against 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) radicals. The antimicrobial effect was tested on Gram-positive and Gram-negative bacterial strains and three fungi from the Candida genus. Cellular counts were measured to determine the cytotoxic effects of the extracts on HEK 293T cell lines. Moreover, spectrophotometrical assays were performed to assess the inhibitory effects of the extracts against the enzymatic activity of α-glucosidase, tyrosinase, and acetylcholinesterase. The MAE resulted in higher yields of polyphenolic compounds and tannins compared to the UAE bark extracts. All of the experimental variants exhibited free-radical-neutralizing properties, especially Q. petraea extracts. Q. petraea extracts also had a more efficient antibacterial effect, especially against Gram-positive bacteria and K. pneumoniae. Antifungal activity was highlighted against C. krusei. Cell counts indicated a cytotoxic effect of the tested extracts against HEK 293T cells. The tested extracts inhibited the activity of α-glucosidase, tyrosinase, and acetylcholinesterase, indicating the potential use of these extracts as antidiabetic, neuroprotective, and skin-protecting agents. These findings highlight the untapped therapeutic potential of the bioactive compounds found in the bark of Q. petraea and Q. pubescens.
Comparison of Artificial Feed and Natural Food by the Growth and Blood Biochemistry in Chinese Sturgeon Acipenser sinensis
Authors: Zheng Yueping , Liu Jiehao , Xu Jianan , Fan Houyong , Wang Youji , Zhuang Ping , Hu Menghong
Published: January 2023

As an endangered animal species, the Chinese sturgeon (Acipenser sinensis) has been artificially cultured during recent years. In the present experiment, the performance of a common formulated feed and a mixed natural feed on the growth and blood physiology of Chinese sturgeon were compared during one year of indoor culture. In terms of specific growth rate, the formulated diet group showed a higher value (4.2%) compared with the natural food group (−1.8%) during one year of indoor culture. Alanine aminotransferase activities of the sturgeons in formulated diet group was significantly higher than that in the natural food group throughout whole experiment period (p < 0.05). The total protein albumin, albumin and globulin contents of the natural food group were significantly higher than that of the formulated diet group in February and May (p < 0.05). The C-reactive protein contents of the formulated diet group were significantly higher than that of natural food group in May and August (p < 0.05). The activities of total cholesterol, high-density cholesterol, and low-density cholesterol were significantly higher in the natural food group than those in the formulated diet group (p < 0.05). The activities of triglycerides were significantly higher in the natural food group than those in the formulated diet group in February and May (p < 0.05). Almost half of the biochemical indicators examined show significant seasonal fluctuations, indicating that seasons have a substantial impact on the Chinese sturgeon. Overall, these results indicate that natural food exerted a positive impact on physiological indicators compared to the formulated diet.
Effect of Beetroot Powder Incorporation on Functional Properties and Shelf Life of Biscuits
Authors: Mitrevski Jasmina , Pantelić Nebojša Đ. , Dodevska Margarita S. , Kojić Jovana S. , Vulić Jelena J. , Zlatanović Snežana , Gorjanović Stanislava , Laličić-Petronijević Jovanka , Marjanović Sonja , Antić Vesna V.
Published: January 2023

The demand for ready-to-use functional foods is high, which encourages manufacturers to develop new, nutritionally valuable products. As an excellent source of biologically active compounds, beetroot (Beta vulgaris L.) is considered to have highly beneficial effects on health. This research aimed to evaluate the impact of replacing spelt flour (SF) with 15%, 20% and 25% beetroot powder (BP). The physicochemical and functional properties of biscuits baked at different temperatures (150 and 170 °C) were followed at the beginning, and after 3 and 6 months of storage as standard conditions. Moisture content and water activity (aw) gave insight into the biscuits’ shelf life. The value of aw from 0.35 to 0.56 indicated appropriate storability. Dietary fiber content in fresh biscuits ranged from 6.1% to 7.6%, protein from 9.2% to 8.9% and sugar from 30.6% to 35.9%. The content of betalain, total polyphenols and flavonoids, and antioxidant activity (DPPH, FRAP) increased with beetroot powder content incorporated. A slight decrease of all the mentioned parameters during the storage indicated satisfied retention of bioactive molecules. The content of prevalent phenolic compounds gallic and protocatechuic acid, identified by HPLC, decreased from 22.2–32.0 and 21.1–24.9 in fresh biscuits to 18.3–23.4 and 17.3–20.3 mg/100 g upon six months of storage, respectively. An increase of the L* and a* and a decrease of the b* coordinate values, compared with the control sample without beetroot values, was noticed as well as the expected level of their change during the storage. The obtained results indicated that biscuits enriched with beetroot powder showed a significantly improved functional, nutritional and antioxidant potential during storage.
Crickets (Acheta domesticus) as Wheat Bread Ingredient: Influence on Bread Quality and Safety Characteristics
Authors: Bartkiene Elena , Zokaityte Egle , Starkute Vytaute , Zokaityte Gintare , Kaminskaite Aura , Mockus Ernestas , Klupsaite Dovile , Cernauskas Darius , Rocha João , Özogul Fatih , Guiné Raquel
Published: January 2023

The aim of this study was to assess respondents’ opinions on the choice of edible insects as a food, and to evaluate the influence of cricket flour (ECF) (10, 20, 30%) on the quality of wheat bread (WB). Whereas ECF is an additional source of acrylamide precursors, in order to reduce acrylamide formation in WB, fermentation of ECF with Lactiplantibacillus plantarum-No.122 was applied. It was established that 70.7% of the respondents had never eaten insects and more than 30% would not choose them. However, ECF was suitable substrate for fermentation (lactobacilli count 8.24 log10CFU/g, pH-4.26). In addition, fermentation reduced the total biogenic amines content in ECF (by 13.1%). The highest specific volume showed WB, prepared with fermented ECF (10, 20, 30%). All the tested WB showed similar overall acceptability (on average, 7.9 points). However, the highest intensity of emotion “happy” was induced by the WB, prepared with fermented ECF. Most of the WB with non-treated and fermented ECF showed higher acrylamide concentration (except WB with 10% of fermented ECF), in comparison with the control. Finally, fermentation is recommended for ECF inclusion in the main WB formula because fermentation improves not only quality but also reduces acrylamide concentration in WB.
Construction of New Infinite-Series Exact Solitary Wave Solutions and Its Application to the Korteweg–De Vries Equation
Authors: Wu Guojiang , Guo Yong
Published: January 2023

The Korteweg–de Vries (KDV) equation is one of the most well-known models in nonlinear physics, such as fluid physics, plasma, and ocean engineering. It is very important to obtain the exact solutions of this model in the process of studying these topics. In the present paper, using distinct function iteration relations in two ways, namely, squaring infinitely and extracting the square root infinitely, which have not been reported in other documents, we construct abundant types of new infinite-series exact solitary wave solutions using the auxiliary equation method. Most of these solutions have not been reported in previous papers. The numerical analysis of some solutions shows complex solitary wave phenomena. Some solutions can have stable solitary wave structures, while others may have singularities in certain space–time positions. The results show that the analysis model we use is very simple and effective for the construction of new infinite-series solutions and new solitary wave structures of nonlinear models.
The Influence of Input Motion Scaling Strategies on Nonlinear Ground Response Analyses of Soft Soil Deposits
Authors: Guzel Yusuf , Elia Gaetano , Rouainia Mohamed , Falcone Gaetano
Published: January 2023

A key issue for the estimation of ground shaking is the proper selection of input motions at the seismic bedrock. At the same time, the effect of the input motion scaling strategy on structural response is typically studied disregarding the presence of the soil deposit. In this work, different soft soil deposits are selected by varying the shear wave velocity profiles and the depth to the seismic bedrock, modelling the soil behaviour through a nonlinear constitutive model implemented into a fully coupled FE code. Seven input motions are retrieved for several selection strategies in conjunction with two seismic intensity levels. Hence, more than 300 one-dimensional ground response analyses are performed. The results of the analysed cases, which are presented in terms of spectral response at ground surface and amplification factors, indicate that: (i) the use of an advanced elasto-plastic soil constitutive model accounts for nonlinear ground response effects, including higher site amplification in the mid-period range and deamplification of the peak ground accelerations; (ii) the different scaling strategies lead to comparable mean values of the amplification factors, and (iii) the variability of the amplification factors is significantly reduced when the scaling strategy seeks the compatibility with the target spectrum over a specified period range. The research will aid the prediction of local seismic site response over large areas, particularly in the absence of the fundamental period of a structure and facilitate its use in general recommendation for quantifying and reducing uncertainty.
Effects of Vernalization on Off–Season Flowering and Gene Expression in Sub-Tropical Strawberry cv. Pharachatan 80
Authors: Thammasophon Thanyarat , Pusadee Tonapha , Bundithya Weenun , Naphrom Daruni
Published: January 2023

Off-season strawberry production may diversify the yield, thereby increasing costs, but the environmental conditions are a limiting factor. This experiment aimed to study the effects of vernalization on off-season flowering and gene expression in sub-tropical strawberry cv. Pharachatan 80. The factorial (2 × 2) + 1 in a completely randomized design was used in this study. Factor A was the vernalization temperatures: 2 °C and 4 °C. Factor B was the vernalization periods: 1 week and 2 weeks, compared with non-vernalization (control). The expression profile of genes was determined after vernalization treatments. The results revealed an interaction between the two factors on the number of days it took the plants to bloom, the percentage of flowering, the number of inflorescences, the number of flowers per inflorescence and the number of flowers per plant, whereas the number of first flower bloom days, inflorescence length and flower size were not affected by the interaction between the two factors. Strawberry plants vernalized for 1 and 2 weeks at 2 °C showed earlier flowering (21.4 and 23.1 days, respectively) than did those vernalized at 4 °C (24.9 and 25.7 days, respectively). On the other hand, non-vernalized strawberry plants took longer to bloom, at 62.2 days. Strawberry plants vernalized at 2 °C for 2 weeks had the highest percentage of flowering, number of inflorescences, number of flowers per inflorescence and number of flowers per plant. The analysis on gene expression showed that VRN5, SOC1 and FT genes were upregulated after vernalization at 2 °C for 2 weeks, whereas gene expression of the control treatment was not detected. This study demonstrates that vernalization treatment could induce off-season flowering in sub-tropical strawberry cv. Pharachatan 80 by activating flowering genes.
Associations between Stressful Life Events and Increased Physical and Psychological Health Risks in Adolescents: A Longitudinal Study
Authors: Roth Anna , Meigen Christof , Hiemisch Andreas , Kiess Wieland , Poulain Tanja
Published: January 2023

Stressful life events (SLEs) are understood as risk factors for mental and physical health problems, particularly in the vulnerable period of adolescence. Using a longitudinal approach, this study investigated associations between SLE and several negative health outcomes in adolescents. Moderating effects of sociodemographic factors were considered. We analyzed the data of a healthy adolescent sample from the LIFE Child study in Leipzig, Germany (n = 2024, aged 10–18 years). SLEs were measured by a questionnaire, addressing SLEs in the family and the social environment domain. Health-related quality of life (HrQoL), behavioral difficulties and BMI were compared before and after an SLE had occurred. Moderator effects of socioeconomic status (SES), age, and sex were investigated using linear regression models. All considered health parameters had, on average, deteriorated after the occurrence of an SLE in the social environment. Differences in HrQoL before and after an SLE were significantly stronger in girls. Higher SES functioned as a slight protective factor against decreased well-being after an SLE. The findings suggest that SLEs function as risk factors for mental and physical health disadvantages in adolescents. Prevention programs should seek to support adolescents in all age and SES groups affected by SLEs, with a specific focus on girls.
Dietary Inflammatory Index (DII)® and Metabolic Syndrome in the Selected Population of Polish Adults: Results of the PURE Poland Sub-Study
Authors: Szypowska Alicja , Zatońska Katarzyna , Szuba Andrzej , Regulska-Ilow Bożena
Published: January 2023

The aim of the study was to assess the relationship between the inflammatory potential of the diets of residents of Lower Silesia, based on the Dietary Inflammatory Index (DII), with the incidence of metabolic syndrome (MetS) and its components. Diets were characterized according to DII terciles. The study group consisted of 1570 individuals enrolled in the Polish arm of the Prospective Urban and Rural Epidemiological (PURE) study. Participants’ diets in DII T1 (most anti-inflammatory diet) had the highest intake of vegetables (except for potatoes), fruits, nuts and seeds, low-calorie beverages, tea, and coffee (all p < 0.001). On the other hand, participants’ diets in DII T3 (most pro-inflammatory diet) contained a lot of whole-fat products, refined cereals, fats (except for vegetable oils), fruit juices, red meat, processed meat/meat products, sugar-sweetened beverages, sweets, sugar, and honey (all p < 0.001). Overall, we did not find an increased prevalence of MetS and its individual components in DII tercile 3 (T3) compared to DII tercile 1 (T1), except for an increased prevalence of abnormal TG in DII T3 compared to T1 (OR 1.34; 95% CI = 1.01 to 1.78) in the crude model. In the adjusted model, a lower prevalence of abnormal fasting glucose (FG) was found in DII T2 compared to DII T1 (OR 0.71; 95% CI = 00.54 to 0.94). Results of this study are informative and provide an important basis for further research on the quality of diet and nutrition.
Investigating and Developing a Practical Domestic-Medication System of Public Health for Chinese Family
Authors: Xu Chen , Zhang Yunyi , Chen Yun , Gong Chao
Published: January 2023

(1) Background: The main research aim of this paper is to investigate the commonly stocked medicines in Chinese households. Firstly, a large number of questionnaires were collected to uncover the problem: most Chinese families have the habit of stocking their family medicine boxes. However, there is a lack of a standardized, systematic, and scientific list of household medicine stockpiles. As a result, there are major problems in stocking medicines in households: (1) There is little connection between the type and quantity of medicines stocked and real life; (2) The expiration date of medicines leads to misuse and waste of medicines; (3) The existing list of medicines can provide little help. (2) Methods: The preliminary drug stock list was summarized through case studies; the authenticity of the questions and the credibility of the list were verified through interviews; the number of different types of drugs and the relationship between the resident’s perception of the importance of drugs and their frequency of use was determined through questionnaires; the authenticity of the list was verified through interviews with senior doctors. (3) Results: We finally composed a scientific and practical list of common household medicines, developed a practical domestic-medication system for Chinese families, and conducted validation studies, which received the approval of senior doctors. (4) Conclusions: (1) Chinese families need to prepare medicines according to the actual composition of the family; (2) Chinese families need a scientific and systematic list of commonly prepared medicines; and (3) in addition to the types of medicines, it is also necessary to consider the number of individual types of medicines to be stocked.
Pathway of Effects of Socioeconomic Status on Rural Left-behind Children to Receive Oral Health Services: A Structural Equation Modeling
Authors: Liu Sichen , Chongsuvivatwong Virasakdi , Zhang Shinan , Thearmontree Angkana
Published: January 2023

In a rural area with a high proportion of left-behind children (LBC), we aimed to identify the pathway of influence of socioeconomic status (SES) on LBCs to receive oral health services after individualized advice. Between September and October 2020, in a rural area of Yunnan, a survey of 238 LBC and 210 non-left-behind children (NLBC) showed that 91.9% and 94.2% had primary teeth caries, respectively. Their caregivers were advised on (1) dental care: bringing the children to seek professional dental care; and (2) self-care: supervising the children’s oral health behaviors. Two to three months later, the children and their caregivers were visited to assess the compliance with these items of advice. Structural equation modeling (SEM) was used to handle the association between SES and compliance with the advice. A heatmap was used to visualize the data of reasons for seeking dental care or not. A total of 183 (87.1%) NLBCs and 206 (86.6%) LBCs were given the above advice; 32.9% of caregivers complied with dental care advice without a statistical difference between the LBC and NLBC group; 69.9% of caregivers of NLBCs complied with self-care advice, statistically more than those LBCs (59.2%). The education of caregivers was significantly associated with compliance with both advice items in univariate analysis. SES had a direct effect on the children being left behind and the level of oral health knowledge and awareness of the caregivers. Being left behind did not have an independent effect on receiving oral health services for children. “Dental disease was not severe” and “having no pain” were the main reasons for not seeking dental care. There was no clear grouping of participants with different background information based on the reasons given for seeking or not seeking dental care. Our study pointed to the importance of SES level. Being left behind alone may not be a risk factor for missing oral health services among rural children.
The Progress of Smart Elderly Care Research: A Scientometric Analysis Based on CNKI and WOS
Authors: Liu Xiaoyun , Chau Ka-Yin , Liu Xiaoxiao , Wan Yan
Published: January 2023

To reduce the burden caused by an increased elderly population and to provide efficient service resources, scholars worldwide have proposed and applied smart elderly care. This paper summarizes the hotspots of the existing literature and explores the research frontiers to ignite future research. CiteSpace software was used to conduct a scientometric analysis of high-quality literature collected from both the China National Knowledge Infrastructure (CNKI) and the Web of Science (WOS). Based on the results of the basic situation description, this article highlights six research hotspots in CNKI and 11 research themes in WOS. In addition, it offers three major evolution stages and three future research directions for smart elderly care research. This paper provides a holistic overview of the smart elderly care literature from two major global databases. The results will contribute to healthcare policy designers, practitioners, and developers by giving them comprehensive knowledge and generating strategies to enhance elderly people’s quality of life.
The Effects of Exercise for Cognitive Function in Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Xu Liya , Gu Hongyi , Cai Xiaowan , Zhang Yimin , Hou Xiao , Yu Jingjing , Sun Tingting
Published: January 2023

Background: Physical exercise can slow down the decline of the cognitive function of the older adults, yet the review evidence is not conclusive. The purpose of this study was to compare the effects of aerobic and resistance training on cognitive ability. Methods: A computerized literature search was carried out using PubMed, Cochrane Library, Embase SCOPUS, Web of Science, CNKI (China National Knowledge Infrastructure), Wanfang, and VIP database to identify relevant articles from inception through to 1 October 2022. Based on a preliminary search of the database and the references cited, 10,338 records were identified. For the measured values of the research results, the standardized mean difference (SMD) and 95% confidence interval (CI) were used to synthesize the effect size. Results: Finally, 10 studies were included in this meta-analysis. Since the outcome indicators of each literature are different in evaluating the old cognitive ability, a subgroup analysis was performed on the included literature. The study of results suggests that aerobic or resistance training interventions significantly improved cognitive ability in older adults compared with control interventions with the Mini-Mental State Examination (MD 2.76; 95% CI 2.52 to 3.00), the Montreal Cognitive Assessment (MD 2.64; 95% CI 2.33 to 2.94), the Wechsler Adult Intelligence Scale (MD 2.86; 95% CI 2.25 to 3.47), the Wechsler Memory Scale (MD 9.33; 95% CI 7.12 to 11.54), the Wisconsin Card Sorting Test (MD 5.31; 95% CI 1.20 to 9.43), the Trail Making Tests (MD −8.94; 95% CI −9.81 to −8.07), and the Stroop Color and Word Test (MD −5.20; 95% CI −7.89 to −2.51). Conclusion: Physical exercise improved the cognitive function of the older adults in all mental states. To improve cognitive ability, this meta-analysis recommended that patients perform at least moderate-intensity aerobic exercise and resistance exercise on as many days as possible in the week to comply with current exercise guidelines while providing evidence for clinicians.
Economic Burdens of Uncomplicated Malaria in Primary Health Care (PHC) Facilities of Plateau State, Nigeria: Patients’ Perspectives
Authors: Ismail Nahlah Elkudssiah , Jimam Nanloh Samuel , Goh Khang Wen , Tan Ching Siang , Ming Long Chiau
Published: January 2023

Objectives: This study aims at evaluating the costs incurred by patients in Primary Healthcare facilities of Plateau State, Nigeria, due to uncomplicated malaria management. Methods: Patients’ information on resources used and absence from the labour market due to uncomplicated malaria illness were collected using the self-reported cost of illness instruments across 24 selected Primary Health Care (PHC) facilities in Plateau State. The collated data were used to estimate the direct medical and non-medical costs incurred by patients through the summation of the various costs paid out of pocket for the services; while the indirect cost was estimated using the human capital theory. All analyses were conducted through Microsoft Excel and IBM Statistical Package for Social Sciences (SPSS®) version 23 software. Results: The average direct cost per episode of uncomplicated malaria was estimated at NGN 2808.37/USD 7.39, while the indirect average money equivalence of the time lost due to the ailment was estimated at NGN 2717/USD 7.55, giving an average cost of treating uncomplicated malaria borne by patients in Plateau State per episode to be NGN 5525.37/USD 14.94. The projected annual cost of the disease was NGN 9, 921,671,307.22 (USD 27, 560,198.08). Conclusions: The study showed substantial financial costs borne by patients due to uncomplicated malaria in Plateau State, comprising 50.83% of direct cost and 49.17% of the indirect cost of medications.