bluuebunny/crossref_metadata_2025 huggingface dataset:
Antecedents of training transfer of management training in the public sector in the Eastern and Southern African Region - A Longitudinal Survey
Authors: Matata Kilungu , Wahida Bana
Published: September 2023

Many organizations world over continue to make huge investments in their human capital through training and development. These efforts would only be worthwhile if such training is transferred into the workplaces and translated into various performance outcomes. The concept of transfer of training has gained a lot of interest among researchers and human resource practitioner alike. However, a consensus has not been reached on the antecedents of training transfer and especially from a developing economy context. The purpose of this study was to establish the factors influencing training transfer of various management training programmes carried out in the public sector organizations in the Eastern and Southern African region. A descriptive research design was employed. A survey of 169 respondents was carried out using a questionnaire. The results indicate that the 16-components of LTSI model were all not confirmed as the findings produced 14 components. The 14 components produced 4 factors influencing intention to transfer: learner readiness’, motivation to transfer, work environment and individual abilities. There is need to undertake further studies in order to establish reasons for inconsistency in the application of the 16-components in this study. Since the study has concentrated on the context of public service, there is also need to undertake similar or comparative studies with employees for private organizations where the work environment seems to be better that in the government.
Teaching old dogs and young dogs new tricks: canine scent detection for seabird monitoring
Authors: Bolton Mark , Morgan Greg , Bolton Susannah , Bolton Jack , Parmor Sarah , Bambini Laura
Published: September 2023

Dogs Canis familiaris have been domesticated for over 11,000 years and have been trained to perform a vast array of tasks. Scent dogs are routinely used to detect elusive animals of conservation concern as well as the presence of invasive nonnative predators. However, a recent review of studies on scent dogs for nature conservation found few peer-reviewed papers on detection of seabirds, and we suggest the potential of scent dogs for seabird monitoring is currently under-utilised. To stimulate wider consideration of the use of scent dogs for seabird monitoring we: (i) document the training, testing and performance of a one-year old Golden Retriever, to detect scent from European Storm Petrels Hydrobates pelagicus, and to differentiate between scent of European Storm Petrels and Manx Shearwaters Puffinus puffinus, and (ii) report on the field performance of a 12-year old Border Collie to detect Manx Shearwaters breeding in natural nest burrows and artificial nest boxes. We show that these individual dogs had a high success rate in locating hidden seabird targets by scent in experimental and field settings and we highlight some of the set-backs encountered during the training process, and their solutions. We show that the detection of occupied Manx Shearwater burrows is dependent on their depth and recent history of occupation. Our results highlight the potential value of scent dogs to establish the presence of particular seabird species at sites where breeding status is currently uncertain, and to map the extent of occupied areas. Further work is needed to validate the use of scent dogs to determine seabird breeding density in real-world situations, where detection probability may be influenced by nest site characteristics and breeding density. We stress the need to involve professionals in the selection, training and testing of scent dogs.
Non-uniform Trajectory Tracking AILC for Nonlinear Time-varying Parameter System with Multiple Unknown Control Directions
Authors: Zhang Chunli , Gao Yangjie , Yan Lei
Published: September 2023

In this paper, a new iterative learning controller is presented for nonlinear time-varying parameter system to solve the tracking problem of different target trajectories. Based on Nussbaum function and the Lyapunov-like synthesis design the learning controller to handle system dynamics with multi-unknown control directions. Over a finite time interval, the unknown time-varying parameter is considered to be periodic, so it is expanded using a Fourier series expansion, and the remaining terms are treated with a canonical series. The controller designed in this paper can ensure that all signals of the closed-loop system are bounded in a finite time interval [0,T], and can complete non-uniform target tracking. Finally, a simulation example is given to verify the effectiveness of the designed controller.
On maximal solution to a degenerate parabolic equation involving in time fractional derivative
Authors: Dai Nghia Bui , Hoang Luc Nguyen , Qin Xiaolan , Wang Yan
Published: September 2023

In this paper, we consider a degenerate parabolic equation associated with Caputo derivative. Our problem is studied in the unbounded domain and the nonlocal initial condition. Under some suitable conditions of the input data, we show the local existence of the mild solution. Then we show the continuation of the mild solution. We also claim the maximal mild solution. The main analysis in the current paper is based on some estimations of resolvent theory combined with many complex valuations on solutions operators in Banach spaces.
Participação discente em projetos de extensão
Authors: Amorim de Sá Lindayane dos Santos , Vinholi Junior Airton José
Published: September 2023

No presente trabalho, buscou-se identificar, por meio de uma pesquisa qualitativa, possíveis impactos da extensão na formação dos estudantes do Instituto Federal de Mato Grosso do Sul (IFMS), Campus Campo Grande. Para esta pesquisa, utilizou-se como instrumento de coleta de dados entrevistas semiestruturadas. As análises foram baseadas nos pressupostos da Análise de Conteúdo de Bardin. Pôde-se perceber que algumas dificuldades permearam questões organizacionais para implementação dos projetos de extensão. Um desafio que se coloca frente aos estudos da presente pesquisa consiste na compreensão do fazer extensionista e em sua concretização, de forma que se promova uma convergência entre instituição e comunidade, por meio de uma relação dialógica. Ressalta-se a importância da busca por uma relação com a comunidade que cumpra, inclusive, os aspectos relativos à responsabilidade social da instituição de ensino. Faz-se necessário, também, que ações extensionistas sejam pauta de reflexão para que haja práticas que contribuam para todos os envolvidos no processo: instituição, estudantes e comunidade externa. Também é preciso promover e divulgar as atividades institucionais de forma a favorecer a participação dos estudantes. O engajamento institucional, assim como os auxílios financeiros, pode contribuir para a formação dos estudantes e colaborar para sua permanência na instituição.
ANALISIS BISNIS JUAL BELI KENDARAAN BEKAS MELALUI MAKELAR BERDASARKAN PERSPEKTIF ISLAM (STUDI KASUS ANANG MOTOR DENPASAR BARAT)
Authors: Nafis  , Agrosamdhyo  , Kurniawati
Published: September 2023

Tujuan penelitian dalam skripsi ini adalah Untuk mengetahui bisnis jual beli kendaraan bekas melalui makelar Anang Motor Denpasar Barat. Untuk mengetahui praktik makelar ditinjau dari perspektif Islam Anang Motor Denpasar Barat. Untuk mengetahui bisnis jual beli kendaraan bekas melalui makelar apakah sudah sesuai dengan perspektif Islam Anang Motor Denpasar Barat. Metodologi penelitian yang digunakan adalah penelitian kualitatif deskriptif. Keabsahan data yang digunakan dalam penelitian ini triangulasi. Informan dalam penelitian ini adalah pemilik Anang Motor, kariyawan sebagai makelar Anang Motor, dan pembeli Anang Motor dengan menggunakan teknik purposive. Serta pengumpulan data berupa: Wawancara, Observasi dan Dokumentasi. Hasil tersebut menunjukkan adanya perbedaan terhadap perspektif Islam.
Learning Deixis In Class Using A Case Study Of Bambang Yudhoyono’s Speech On Climate Change Conference
Authors: Jatmikawati Linanda
Published: September 2023

This writing is entitled “Deixis of Bambang Yudhoyono’s Speech in Climate Change Conference”. It is aimed at finding the types of deixis that has in two speeches of Bambang Yudhoyono in climate change conference, to analyze how the deixis expressions and the deictic markers are presented in the speech.

This speech also has discourse deixis elements such as: it, this/ these and that/those. Social deixis in these speeches only used Arabic term. The percentages of deictic markers in these speeches are dominated by the deictic markers of person and deictic marker of discourse.
Marketing Mix Pada PT. Bank BNI Syariah Kantor Cabang Denpasar Bali
Authors: Agrosamdhyo Raden
Published: September 2023

Penelitian ini memiliki tujuan untuk mengetahui bagaimana kegiatan Marketing Mix pada PT. Bank BNI Syariah Cabang Denpasar. Menjelaskan kegiatan dalam  Marketing Mix produk simpanan menggunakan strategi bauran pemasaran atau Marketing Mix yang terdiri dari konsep 7P yaitu : Product (Produk), Price (Harga), Place (Tempat), dan Promotion (Promosi), People (Orang), Process (Proses), dan Physical Evidence (Fasilitas Fisik).
Strategi Penyaluran Zakat Produktif Melalui Program Senyum Usaha Dalam Pemberdayaan Ekonomi Di Lembaga Amil Zakat Dompet Sosial Madani Wilayah Denpasar Bali
Authors: Ria Ashari  , R Agrosamdhyo  , Kurniawati Kurniawati
Published: September 2023

Kemiskinan merupakan masalah yang tidak bisa dianggap mudah untuk dicarikan solusinya karena sudah ada sejak lama, dan menjadi kenyataan yang hidup di tengah masyarakat. Salah satu cara menanggulangi kemiskinan adalah dukungan orang yang mampu untuk mengeluarkan harta kekayaan mereka berupa dana zakat kepada mereka yang kekurangan. Tujuan penelitian ini adalah 1) Untuk mengetahui strategi penyaluran zakat produktif melalui program senyum usaha dalam pemberdayaan ekonomi di DSM Wilayah Denpasar Bali, 2) Untuk mengetahui peran penyaluran zakat produktif melalui program senyum usaha dalam pemberdayaan ekonomi mustahik. Jenis penelitian ini adalah deskriptif dengan pendekatan kualitatif, menggunakan metode observasi, wawancara, dan dokumentasi. Subjek penelitian ini terdiri dari 12 informan yang dipilih dengan menggunakan teknik Purposive. Teknik analisis data yang digunakan meliputi; reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian yang diperoleh: 1) Strategi yang digunakan oleh Dompet Sosial Madani Wilayah Denpasar Bali dalam menyalurkan dana zakat yaitu: Penyaluran dana zakat yang bersifat produktif. DSM Bali melakukan pemberdayaan kepada mustahik berupa, pelatihan dan pendampingan kewirausahaan untuk mustahik. 2) Peran penyaluran zakat produktif  melalui program senyum usaha dalam pemberdayaan  ekonomi adalah mustahik mampu meningkatkan kebutuhan ekonomi bagi keluarganya terutama kebutuhan pokok sehari-hari.
Analisis Penggunaan Aplikasi Gopay Bagi Donatur Dalam Menyaluran Dana Zakat, Infaq, Sedekah (ZIS) Di Badan Amil Zakat Nasional (BAZNAS) Provinsi Bali
Authors: Syahrir Ramadhany  , Ely Mansur  , Kurniawati Kurniawati
Published: September 2023

Alat pembayaran itu mulanya dikenal berupa sistem barter antar barang yang diperjual-belikan lalu berkembang menjadi uang tunai (cash based) dan selanjutnya ke alat pembayaran nontunai (non cash). Mengetahui akan pentingnya berzakat, infaq, sedekah masa kini di tengah pesatnya perkembangan teknologi, fitur pembayaran digital dalam sebuah instansi sangat dibutuhkan. Baznas Provinsi Bali pun menggunakan salah satu aplikasi berbayar non tunai yaitu Gopay. Tujuan dari penelitian ini ialah: Untuk mengetahui penggunaan aplikasi Gopay bagi donatur dalam menyaluran dana zakat, infaq, sedekah (ZIS) di Badan Amil Zakat Nasional (BAZNAS) Provinsi Bali.  Untuk mengetahui aplikasi Gopay menjadi pilihan donatur dalam menyaluran dana zakat, infaq, sedekah (ZIS) di Badan Amil Zakat Nasional (BAZNAS) Provinsi Bali. Metode penelitian ini menggunakan metode deskriptif dengan pendekatan kualitatif. Informan akan dipilih dengan menggunakan teknik purposive. Pengumpulan data yang diperoleh berdasarkan fakta dan data dilapangan. Sumber data ialah sumber data primer dan sekunder melalui teknik pengumpulan data Observasi, Wawancara, dan Dokumentasi. Teknik analisa data meliputi: Reduksi data, Penyajian data, Pengambilan kesimpulan atau vertifikasi.  Uji keabsahan data: Triangulasi. Hasil penelitian mengungkapkan bahwa Donatur beranggapan bahwa penggunaan aplikasi gopay dalam penyaluran dana ZIS sangat praktis, banyak fitur gopay yang menarik dan memudahkan penggunanya. Alasan donatur memilih menggunakan aplikasi gopay karena penggunaanya yang mudah,dapat bertransaksi kapanpun dimanapun cukup dengan scan barcode, jarang terjadi trouble, dapat juga digunakan untuk transaksi sehari-hari, dan gopay juga memberikan promo dan cashback yang menarik.
Analisis Laporan Keuangan Dana Zakat Infak Sedekah (ZIS) Berdasarkan Pernyataan Standar Akuntansi Syariah (PSAK) 109 (Studi Kasus Di Baznas Kota Denpasar)
Authors: Siti Komariah  , Raden Agrosamdhyo  , Agus Hendra Gunawan
Published: September 2023

Transparansi dan akuntabilitas dalam pengelolaan keuangan zakat menjadi sebuah kemestian, karena zakat merupakan amanah dari para muzakki yang dititipkan untuk didistribusikan kepada para mustahik dengan penuh amanah dan tanggung jawab. Media transparansi dan akuntabilitas adalah dengan menyajikan laporan keuangan yang sesuai dengan standar akuntansi yang diterima umum. Tujuan penelitian adalah untuk mengetahui: 1) Analisis laporan keuangan dana ZIS Baznas Kota Denpasar berdasarkan PSAK 109, 2) Dampak yang diterima oleh Baznas Kota Denpasar sejak menerapkan PSAK 109 dalam menyajikan laporan keuangan dana ZIS. Metode penelitian ini menggunakan metode deskriptif dengan pendekatan kualitatif. Informan terdiri dari 7 orang yang dipilih dengan menggunakan teknik purposive sampling. Pengumpulan data yang diperoleh berdasarkan observasi, wawancara, dan dokumentasi. Teknik analisisis data meliputi reduksi data, penyajian data, dan penarikan kesimpulan dan verifikasi. Berdasarkan hasil penelitian menunjukkan Baznas Kota Denpasar telah menunjukkan kualitas pencatatan transaksi yang baik dengan menggunakan double entry yang sesuai dengan PSAK 109. Dalam PSAK 109 terdapat empat indikator pencatatan keuangan dana ZIS yakni pengakuan, pengukuran, penyajian, dan pengungkapan. Namun untuk sementara, Baznas Kota Denpasar masih belum melakukan pencatatan dalam hal pengukuran. Dalam hal penyajian laporan keuangan, Baznas Kota Denpasar menyajikan laporan posisi keuangan, laporan perubahan dana, laporan arus kas, dan catatan atas laporan keuangan, sedangkan laporan perubahan aset kelolaan tidak disajikan. Dampak yang diterima oleh Bazas Kota Denpasar sejak menerapkan PSAK 109 dalam laporan keuangan dana ZIS yaitu laporan keuangan lebih akuntabel dan mudah dipahami, tersusun rapi dan terstruktur, dan menambah trust atau keyakinan masyarakat.
Analisis Pendistribusian Zakat Profesi Untuk Beasiswa Pendidikan (Studi Kasus Baznas Kota Denpasar)
Authors: Rizka Cynthia  , Kusjuniati Kusjuniati  , Kurniawati Kurniawati
Published: September 2023

Baznas Kota Denpasar sebagai badan amil zakat yang dibentuk oleh pemerintah memiliki program-program dalam pendistribusian zakat profesinya, salah satunya ialah program beasiswa pendidikan. Dalam program ini Baznas Kota Denpasar membantu biaya pendidikan anak-anak yang orang tuanya kurang mampu, agar anak tersebut dapat terus melanjutkan sekolah. Bantuan tersebut berupa bantuan SPP setiap bulannya, yang dalam pelaksanaannya dibantu oleh Unit Pengumpul Zakat. Tujuan penelitian adalah untuk mengetahui: 1) Efektivitas pendistribusian zakat profesi untuk beasiswa pendidikan di MI Permata Hati oleh Baznas Kota Denpasar dan 2) Manfaat pendistribusian zakat profesi untuk beasiswa pendidikan di MI Permata Hati oleh Baznas Kota Denpasar. Metode penelitian ini menggunakan metode deskriptif dengan pendekatan kualitatif. Informan terdiri dari 10 orang yang dipilih dengan menggunakan teknik purposive. Pengumpulan data yang diperoleh berdasarkan fakta dan data melalui observasi, wawancara, dan dokumentasi. Teknik analisisis data meliputi reduksi data, penyajian data, dan penarikan kesimpulan. Berdasarkan hasil penelitian menunjukkan bahwa Pendistribusian zakat profesi untuk beasiswa pendidikan di MI Permata Hati sudah berjalan dengan efektif, hal ini dibuktikan dengan zakat yang didistribusikan sudah diberikan tepat kepada orang-orang yang membutuhkan. Zakat yang didistribusikan dalam bentuk SPP setiap bulannya ini, juga sudah dapat meringankan beban biaya pendidikan mustahik. Dan dalam program pendampingan kepada mustahik masih perlu ditingkatkan kembali. Manfaat dari pendistribusian zakat untuk beasiswa pendidikan di MI Permata Hati ini yaitu dapat membantu anak-anak dalam melanjutkan pendidikan, serta bersemangat dalam menuntut ilmu.
Viking Age Windows
Authors: Sode Torben , Jessen Mads Dengsø , Gratuze Bernard
Published: September 2023

In the last 25 years a conspicuous amount of plane glass – windowpane fragments – has surfaced on archaeological sites from the Viking Age. These finds have not received scholarly attention as they are not recognised as a genuine prehistoric (i.e. pre-1050 Scandinavia) occurrence. This paper aims to investigate a select group of archaeological localities that all have a significant amount of glass objects and fragments, and which also serve as mainstays for continental influences, commercial trade, as well as ritual activities. It offers the study of the chemical composition of these windowpane fragments, their distribution, provenience, and discusses their potential use as windows in Viking Age Scandinavia. Based on the chemical composition of the analysed plane glass (via LA-ICP-MS) the paper argues, firstly, that the glass most likely should be dated to the 9th to 11th centuries; secondly, that there are two possible import paths of raw material with one recognized at the early emporia based on east Mediterranean types of glass, and another with a continental type of glass found at the aristocratic sites. Finally, the paper argues that the windowpanes very likely could have been used in contemporary glassed windows placed in wooden buildings at these sites.
VERDENSMÅLENE – en udfordring for hele samfundet
Authors: Ploug Niels
Published: September 2023

FN’s generalforsamling vedtog i 2015 17 verdensmål for bæredygtig udvikling. De kom som en efterfølger til FN’s mål fra år 2000 – de såkaldte Årtusinde-mål (millenium development goals) – for udvikling af især udviklingslande frem mod år 2015, og som havde været en stor succes ikke mindst når det gælder bekæmpelse af fattigdom. Men de nye verdensmål kom til at omfatte alle FN’s 193 medlemslande, og de har med 17 mål mod tidligere 8 fokus på en bæredygtig udvikling på langt flere områder. Bæredygtighed forbindes ofte med miljø- og klimaområdet, men målene dækker også økonomi, økonomisk vækst, sundhed, uddannelse, by-udvikling, arbejdsforhold og meget, meget mere.
Verdensmålene – en dagsorden for fremtiden
Authors: Jensen Kristian
Published: September 2023

Verdensmålene understøtter en væsentlig og ambitiøs dagsorden på afgørende vigtige områder, der alle spiller en stor rolle politisk både nationalt og internationalt. De er ambitiøse, og derfor kræves der en omfattende indsats fra alle sider i samfundet for at nå dem.
Immer Besser – fra global til lokal: Indsatsen i kommunerne
Authors: Kildesgaard Laila , Johannsen Lone
Published: September 2023

Kommunerne er centrale leverandører af offentlige serviceydelser, som kan være drivkraft i Danmarks indsats for at komme i mål i 2030.I mange henseender er det derfor lokalt, at Verdensmålene kan oversættes til konkrete løsninger og indsatser.
Fagbevægelsen og Verdensmålene
Authors: Højlund Nanna , Grevsen Arne
Published: September 2023

I denne her artikel vil vi forsøge at give vores bud på, hvad vi mener, at Verdensmålene kan, og hvad de ikke kan – set med fagbevægelsens briller. Vi vil også give nogle bud på, hvordan Danmark kan speede udviklingen op, så vi rent faktisk kan lykkes komme i mål med Verdensmålene, inden vi skriver 2030 i kalenderen.
Single magnetic impurity effects in graphene based superconductors
Authors: Zhao Zong-Yang , Li Ming , Zhou Tao ,   Guangdong-Hong Kong Joint Laboratory of Quantum Matter, Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials, School of Physics, South China Normal University, Guangzhou 510006, China
Published: September 2023

The magnetic impurity effects and the existence of bound states (i.e. Yu-Shiba-Rusinov states) in superconductors have been a topic of great interest. Recently, the existence of Yu-Shiba-Rusinov states in graphene-based superconducting materials has been successfully observed in the laboratory. In this work, an effective Hamiltonian in real space is established to describe the superconducting state of graphene materials by considering a single magnetic impurity. Thus the Bogoliubov-de Gennes (BdG) equation is constructed and the self-consistency calculations of the superconducting order parameter are conducted. On this basis, the effects of magnetic impurities on graphene-like superconductors are investigated theoretically. The numerical results show that the Yu-Shiba-Rusinov state can only appear in the symmetry of the superconducting pair of the traditional s-wave coupling. The position and strength of the bound state are related to the magnetic moment of the impurity, showing a notable electron-hole asymmetry. There are no bound states in the energy gap for other pairing symmetries. This theoretical calculation not only provides a reasonable explanation for experimental phenomena, but also demonstrates that the heterojunction system composed of graphene and traditional superconductors has an s-wave superconducting pairing induced by the proximity effect in the graphene layer.
Phase transition regulation, magnetocaloric effect, and abnormal thermal expansion
Authors: Lin Yuan , Hu Feng-Xia , Shen Bao-Gen ,   State Key Laboratory of Magnetism, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China,   Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, Ningbo 315201, China,   School of Physical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China,   Songshan Lake Materials Laboratory, Dongguan 523808, China
Published: September 2023

As a common phenomenon in nature, phase transition has received much attention for a long time. It has been applied to various fields, such as refrigeration, information and energy storage, and negative thermal expansion. Solid refrigeration technology based on magnetocaloric effect, electrocaloric effect, and mechanocaloric effect has the advantages of environmental protection, high efficiency, no noise, and easy miniaturization, and is expected to replace vapor compression technology. Among them, the magnetocaloric effect has the longest research history. However, the shortcomings of magnetocaloric effect driven by a single magnetic field limit its solid-state refrigeration application, such as insufficient amplitude of caloric effect, large hysteresis loss, and narrow refrigeration temperature span. To solve these problems, multifield tuning and multicaloric effect have come into people's sight. This paper introduces our recent research on improving the caloric effect by applying multifield, such as increasing entropy change, expanding transition temperature range, adjusting transition temperature, and reducing hysteresis losses. The thermodynamics of multifield and coupled-caloric effect are presented in the meantime. On the other hand, materials with abnormal thermal expansion (zero thermal expansion, negative thermal expansion) have important applications in precision manufacturing. The phase transition and lattice effect dominated by magnetic atoms in the giant magnetocaloric materials with strong magnetic-crystal coupling provide an ideal platform for exploring abnormal thermal expansion. This paper also introduces our recent research on abnormal thermal expansion in magnetocaloric materials, and looks forward to future relevant research.
Comparison of Two Different Implants in Medial Malleolus Fracture
Authors: Uluöz Mesut
Published: September 2023

Background: We compared two different techniques used in medial malleolus fracture. It has been hypothesized that the hook plate technique, which has become widespread in recent years, may have an advantage over cannulated screws.

Methods: Preoperative and postoperative data for medial malleolus fractures operated on between 2010 and 2020 were analyzed retrospectively. Patients were divided into those operated on with a hook plate (n = 20) and those operated on with compression screws (n = 20) and were compared in terms of complications, pain, functional recovery, union success, and ankle joint range of motion. Fracture union times were recorded.

Results: Between groups, there were no significant differences in time to fracture union, pain, range of motion, and American Orthopaedic Foot and Ankle Society score (P = .420). Handling of the implant in a very weak patient in the hook plate group and revision in the cannulated screw group were the differences in complications between groups. The use of hook plates in a patient with medial malleolus fracture with metaphyseal fracture provided significant convenience in osteosynthesis.

Conclusions: Use of hook plates provides serious advantages to the surgeon in medial malleolus fractures with small or fragmented fragments and combined with malleolus metaphyseal fractures. Having a larger implant versus a cannulated screw is seen as a disadvantage, but screwing the implant close to the cortex increases its strength. Therefore, its use should be given priority in patients who are mentally unable to weightbear after surgery. Although hook plate is advantageous compared with cannulated screw in appropriate indications, it can be used safely in all malleolus fractures where cannulated screws are used.
Intraobserver and Interobserver Reliability of the Computed Tomography–Based Classifications Used in Posterior Malleolar Fractures: The Haraguchi and Bartoníček-Rammelt Classifications
Authors: Turgut Ali , Egeli Ercüment , Altundağ Ümit , Sarıekiz Emre , Erkuş Serkan , Kalenderer Önder
Published: September 2023

Background: Three main computed tomography (CT)–based classification systems have been defined and used for posterior malleolar fractures. The intraobserver and interobserver reliability of two of these systems has never been investigated. The aim of this study was to investigate the intraobserver and interobserver reliability of the Haraguchi (HC) and Bartoníček-Rammelt (BRC) classifications.

Methods: Axial and sagittal CT sections and three-dimensional reconstruction images of 60 fractures were evaluated twice by six observers at a 6-week interval. Cohen κ values for intraobserver reliability and Fleiss κ values for interobserver reliability were calculated.

Results: The interobserver reliability of the HC was fair in both assessments (Fleiss κ: 0.263 and 0.249 for the first and second evaluations, respectively). The interobserver reliability of the BRC was moderate in both evaluations (Fleiss κ: 0.535 and 0.447, respectively). The intraobserver reliability values (Cohen κ) of the HC were determined to be between 0.532 and 0.927 for the six observers. These values indicated moderate agreement for one observer, substantial for four, and very good for one. Intraobserver reliability values for the BRC were determined to be between Cohen κ of 0.626 and 0.884. Based on these values, the BRC's intraobserver reliability indicated substantial agreement for two observers and very good for four observers.

Conclusions: Intraobserver and interobserver reliability values of the BRC were higher than those of the HC.
Coronal Shearing Fracture of the Talar Body with Talar Head Dislocation Related to a Navicular Compression Fracture: A Rare Case Report
Authors: Van Minh Do , Thang Hoang Minh , Son Nguyen Moc , Thanh Dao Xuan
Published: September 2023

A talar body fracture is typically associated with talar body dislocation, resulting in ankle and subtalar joint subluxation and/or dislocation. A talar body fracture with talar head dislocation is a very rare injury. In this report, we describe the case of a 23-year-old man who suffered a coronal shearing fracture of the talar body with talar head dislocation related to a navicular compression fracture. The patient sought orthopedic consultation 6 weeks after injury. The injury was managed with open reduction, talar head relocation, internal fixation of the talar body fracture with Kirschner wires and cancellous screws and talonavicular fusion with an iliac bone autograft. Follow-up 4 years after operative treatment showed that the patient had satisfactory treatment results, including good bone healing with minimal changes in the anterior talotibial compartment and excellent function of the hindfoot and ankle.
Endoscopic Plantar Fasciotomy as an Effective and Reliable Treatment for Plantar Fasciitis: An Overview of the Literature
Authors: Papathanasiou Maria , Georgoulas Paraskevas , Perikleous Evanthia , Tilkeridis Konstantinos , Ververidis Athanasios , Drosos Georgios
Published: September 2023

Plantar fasciitis is a common cause of heel pain. The aim of this study was to review the current literature and attempt to clarify whether endoscopic plantar fasciotomy (EPF) is an effective and reliable treatment for plantar fasciitis in comparison with other invasive or noninvasive treatments. We performed an electronic search of the medical literature in PubMed database using combinations of the following keywords: plantar fasciitis, endoscopic treatment, and plantar aponeurosis. Overall, we had shown that patients had better scores following EPF/endoscopic plantar fascia release. The clinical scores were improved postoperatively and most of the patients were satisfied. Furthermore, the clinical trials showed that time to return to work or to previous activities was shorter compared with other treatments. These studies suggest that EPF/endoscopic plantar fascia release is probably an effective treatment of chronic plantar fasciitis. EPF is an efficient, safe treatment with good early postoperative results in patients with recalcitrant plantar fasciitis. There is evidence that other methods are equivalently effective for EPF, and some authors support that they should be considered as a second-line treatment because of their minimal invasive character and very low risk of complications; thus, more research is required.
Repair of Distal Fibula Fractures with Minimally Invasive Intramedullary Nailing in the Elderly
Authors: Bridges Rayven , Saulabiu Angelica
Published: September 2023

Ankle fractures have been well documented and are common, especially in the elderly, behind hip and distal radius fractures. Open reduction and internal fixation (ORIF) is the standard of treatment for displaced and unstable ankle fractures. Traditionally, ankle fractures in the elderly population have been treated with nonoperative methods; however, nonoperative methods have been associated with increased mortality. Thus, there has been a shift toward operative management for the elderly and less healthy patients. However, these patients often present with more comorbidities that make them not ideal candidates for ORIF of the fracture. Minimally invasive intramedullary nailing of the fibula has gained popularity in recent years for the treatment of displaced ankle fractures. A 72-year-old man presented to the clinic with left ankle pain with a duration of 2 weeks. Radiography revealed a displaced fracture of the left fibula at the level of the ankle joint. This case report documents the surgical treatment of a displaced distal fibula fracture using minimally invasive intramedullary nailing of the fibula. At 4 months’ follow-up, the patient was walking with minimal assistance and weightbearing as tolerated. Left untreated, displaced ankle fractures can be very debilitating, with increased mortality and morbidity, especially in the elderly population. Thus, early diagnosis and surgical treatment of displaced ankle fractures are imperative. The purpose of this report was to raise awareness of minimally invasive fibular nailing as an alternative to ORIF in the treatment of displaced ankle fractures in the elderly.
Associative memory neurons of encoding multi-modal signals are recruited by neuroligin-3 mediated new synapse formation
Authors: Xu Yang , Cui Tian-Liang , Li Jia-Yi , Chen Bingchen , Wang Jin-Hui
Published: September 2023

The joint storage and reciprocal retrieval of leant associated signals are presumably encoded by associative memory cells. In the accumulation and enrichment of memory contents in lifespan, a signal often becomes a core signal associatively shared for other signals. One specific group of associative memory neurons that encode this core signal likely interconnects multiple groups of associative memory neurons that encode these other signals for their joint storage and reciprocal retrieval. We have examined this hypothesis in a mouse model of associative learning by pairing the whisker tactile signal sequentially with the olfactory signal, the gustatory signal and the tail-heating signal. Mice experienced this associative learning show the whisker fluctuation induced by olfactory, gustatory and tail-heating signals, or the other way around, i.e., memories to multi-modal associated signals featured by their reciprocal retrievals. Barrel cortical neurons in these mice become able to encode olfactory, gustatory and tail-heating signals alongside the whisker signal. Barrel cortical neurons interconnect piriform, S1-Tr and gustatory cortical neurons. With the barrel cortex as the hub, the indirect activation occurs among piriform, gustatory and S1-Tr cortices for the second-order associative memory. These associative memory neurons recruited to encode multi-modal signals in the barrel cortex for associative memory are downregulated by neuroligin-3 knockdown. Thus, associative memory neurons can be recruited as the core cellular substrate to memorize multiple associated signals for the first-order and the second-order of associative memories by neuroligin-3-mediated synapse formation, which constitutes neuronal substrates of cognitive activities in the field of memoriology.

The coactivity of cerebral cortices during associative learning induces their interconnections.

Interconnections endorse the first order and the second order of associative memory.

Associative memory cells in cerebral cortices are recruited by mutual synapse innervations.

Neuroligin-3 mediates the recruitment of associative memory cells for associative memory.
Cortical Plasticity is associated with Blood-Brain-Barrier Modulation
Authors: Swissa Evyatar , Monsonego Uri , Yang Lynn T. , Schori Lior , Kamintsky Lyna , Mirloo Sheida , Burger Itamar , Uzzan Sarit , Patel Rishi , Sudmant Peter H , Prager Ofer , Kaufer Daniela , Friedman Alon
Published: September 2023

Brain microvessels possess the unique properties of a blood-brain barrier (BBB), tightly regulating the passage of molecules from the blood to the brain neuropil and vice versa. In models of brain injury, BBB dysfunction and the associated leakage of serum albumin to the neuropil have been shown to induce pathological plasticity, neuronal hyper-excitability, and seizures. The effect of neuronal activity on BBB function and whether it plays a role in plasticity in the healthy brain remain unclear. Here we show that neuronal activity induces modulation of microvascular permeability in the healthy brain and that it has a role in local network reorganization. Combining simultaneous electrophysiological recording and vascular imaging with transcriptomic analysis in rats, and functional and BBB-mapping MRI in human subjects we show that prolonged stimulation of the limb induces a focal increase in BBB permeability in the corresponding somatosensory cortex that is associated with long-term synaptic plasticity. We further show that the increased microvascular permeability depends on neuronal activity and involves caveolae-mediated transcytosis and transforming growth factor beta signaling. Our results reveal a role of BBB modulation in cortical plasticity in the healthy brain, highlighting the importance of neurovascular interactions for sensory experience and learning.
Heterogeneity of radial spokes structural components and associated enzymes in Tetrahymena cilia
Authors: Bicka Marta , Black Corbin , Ghanaeian Avrin , Joachimiak Ewa , Osinka Anna , Majhi Sumita , Konopka Anna , Bulska Ewa , Bui Khanh Huy , Wloga Dorota
Published: September 2023

Radial spokes (RS), the T-shaped, multiprotein complexes of motile cilia, transmit regulatory signals from the central apparatus to the outer doublet complexes, including inner dynein arms. In the vast majority of ciliated species, RSs assemble as repeats of triplets (RS1-RS2-RS3), and each spoke is associated with a different subset of inner dynein arms. Studies in
Chlamydomonas
and mice sperm flagella led to the identification of RS proteins (RSPs) and revealed that some structural components are either RS1- or RS2-specific. In contrast, the protein composition of RS3 remains largely unknown. We used the ciliate
Tetrahymena thermophila
to investigate the protein composition of individual RSs, including the poorly characterized RS3. The
Tetrahymena
genome encodes three RSP3 paralogs. Using engineered
RSP3
knock-out mutants and previously studied RS mutants with
CFAP61
,
CFAP91
, or
CFAP206
deletion and complementary approaches, including bioinformatics, total ciliome comparisons, and cryo-electron tomography with subtomogram averaging, we identified
Tetrahymena
RSP orthologs and solved the composition of individual RSs, showing their subunit heterogeneity. We found that RSP3 proteins are components of RS1 and RS2 but not RS3. Based on the presence of the RSP3 paralog, we distinguished sub-types of RS1 (RSP3A- or RSP3B-containing) and RS2 spokes (RSP3B- or RSP3C-containing). We identified novel RS-associated proteins, including several enzymes that may locally regulate ADP/ATP levels, GMP-recycling-related enzymes, and enzymes regulating phosphorylation levels. These discoveries will help to better understand the molecular mechanism(s) that regulate cilia beating and overall cilia metabolism.Identification of the subtypes of RS1 and RS2 spokes and RS1-3-specific RSPs. Discovery of the novel radial spoke structural components and RS-associated enzymes regulating ADP/ATP ratio and protein phosphorylation.
Synthetic eco-evolutionary dynamics in simple molecular environment
Authors: Casiraghi Luca , Mambretti Francesco , Tovo Anna , Paraboschi Elvezia Maria , Suweis Samir , Bellini Tommaso
Published: September 2023

The understanding of eco-evolutionary dynamics, and in particular the mechanism of coexistence of species, is still fragmentary and in need of test bench model systems. To this aim we developed a variant of SELEX in vitro selection to study the evolution of a population of ∼1015 single-strand DNA oligonucleotide ‘individuals’. We begin with a seed of random sequences which we select via affinity capture from ∼1012 DNA oligomers of fixed sequence (‘resources’) over which they compete. At each cycle (‘generation’), the ecosystem is replenished via PCR amplification of survivors. Massive parallel sequencing indicates that across generations the variety of sequences (‘species’) drastically decreases, while some of them become populous and dominate the ecosystem. The simplicity of our approach, in which survival is granted by hybridization, enables a quantitative investigation of fitness through a statistical analysis of binding energies. We find that the strength of individual resource binding dominates the selection in the first generations, while inter- and intra-individual interactions become important in later stages, in parallel with the emergence of prototypical forms of mutualism and parasitism.
The 14-3-3/spastin pathway coordinates neurite regeneration and recovery of spinal cord injury by targeting microtubule dynamics
Authors: Liu Qiuling , Yang Hua , Luo Jianxian , Peng Cheng , Wang Ke , Zhang Guowei , Ji Zhisheng , Lin Hongsheng
Published: September 2023

Axon regeneration is abortive in the central nervous system following injury. Orchestrating microtubule dynamics has emerged as a promising approach to improve axonal regeneration. The microtubule severing enzyme spastin is essential for axonal development and regeneration through remodeling of microtubule arrangement. To date, however, little is known regarding the mechanisms underlying spastin action in neural regeneration after spinal cord injury. Here, we use glutathione transferase pulldown and immunoprecipitation assays to demonstrate that 14-3-3 interacts with spastin, both
in vivo
and
in vitro,
via spastin Ser233 phosphorylation. Moreover, we show that 14-3-3 protects spastin from degradation by inhibiting the ubiquitination pathway and upregulates the spastin-dependent severing ability. Furthermore, improving the interaction between 14-3-3 and spastin by Fusicoccin (FC-A) promotes neurite outgrowth and regeneration
in vitro
. Western blot and immunofluorescence results revealed that 14-3-3 protein is upregulated in the neuronal compartment after spinal cord injury
in vivo
. In addition, administration of FC-A not only promotes locomotor recovery, but also nerve regeneration following spinal cord injury in both contusion and lateral hemisection models. However, application of spastin inhibitor spastazoline successfully reverses these phenomena. Taken together, these results indicate that 14-3-3 is a molecular switch that regulates spastin protein levels, and 14-3-3/spastin pathway is an important target for regulation of microtubule dynamics for nerve regeneration after spinal cord injury.
Non-cognate immunity proteins provide broader defenses against interbacterial effectors in microbial communities
Authors: Knecht Abigail , Sirias Denise , Utter Daniel R , Gibbs Karine A
Published: September 2023

Dense microbial communities, like the gut and soil microbiomes, are dynamic societies. Bacteria can navigate these environments by deploying proteins that alter foreign cells’ behavior, such as interbacterial effectors. Current models suggest that adjacent sibling cells are protected by an immunity protein, as compared to toxin-antitoxin systems that act only within the effector-producing cell. A prevailing hypothesis is that immunity proteins binding to specific (cognate) protein partners is sufficient to disrupt effector function. Further, there is little-to-no crosstalk with other non-cognate effectors. In this research, we build on sporadic reports challenging these hypotheses. We show that immunity proteins from a newly defined protein family can bind and protect against non-cognate PD-(D/E)XK-containing effectors from diverse phyla. We describe the domains essential for binding and function and show that binding alone is insufficient for protective activity. Moreover, we found that these effector and immunity genes co-occur in individual human microbiomes. These results expand the growing repertoire of bacterial protection mechanisms and the models on how non-cognate interactions impact community structure within complex ecosystems.
Educational Ideas on the Move
Authors: Juul-Wiese Thilde
Published: September 2023

Based on ethnographic fieldwork amongst Danish student teachers, this paper examines international teaching internships from a mobilities and spatial perspective. While the international teaching internship is regarded as a tool to develop student teachers’ intercultural competencies, this paper shows how culturally shaped educational ideas travel with and are practiced by student teachers in new educational and cultural contexts. Therefore, this paper suggests that such internships may perpetuate and reinforce normative ideas about pedagogy and ‘correct’ ways of teaching, being a pupil, and a teacher. The paper finds that student teachers see some educational ideas and practices as universal and applicable everywhere and others as particular and spatially bound. This, the paper argues, reflects a hierarchisation of ideas based on an assumption of the superiority of ‘Western’ education, which results in processes of pedagogical othering. The paper further argues that international teaching internships represent an important avenue to critically discuss educational values and examine how values impact pedagogical practice, furthering students’ professional development.
Comparative expression analysis of sucrose phosphate synthase gene family in a low and high sucrose Pakistani sugarcane cultivars
Authors: Niazi Robi , Parveen Gulnaz , Noman Muhammad , Mukhtar Naila , Hadayat Naila , Sami Amtul , Khaliq Binish , Shrestha Jiban , Ullah Irfan
Published: September 2023

Sugarcane is the world’s largest cultivated crop by biomass and is the main source of sugar and biofuel. Sucrose phosphate synthase (SPS) enzymes are directly involved in the synthesis of sucrose. Here, we analyzed and compared one of the important gene families involved in sucrose metabolism in a high and low sucrose sugarcane cultivar. A comprehensive in silico analysis of the SoSPS family displayed their phylogenetic relationship, gene and protein structure, miRNA targets, protein interaction network (PPI), gene ontology and collinearity. This was followed by a spatial expression analysis in two different sugarcane varieties. The phylogenetic reconstruction distributed AtSPS, ZmSPS, OsSPS, SoSPS and SbSPS into three main groups (A, B, C). The regulatory region of SoSPS genes carries ABRE, ARE, G-box, and MYC as the most dominant cis-regulatory elements. The PPI analysis predicted a total of 14 unique proteins interacting with SPS. The predominant expression of SPS in chloroplast clearly indicates that they are the most active in the organelle which is the hub of photosynthesis. Similarly, gene ontology attributed SPS to sucrose phosphate synthase and glucosyl transferase molecular functions, as well as sucrose biosynthetic and disaccharide biological processes. Overall, the expression of SPS in CPF252 (high sucrose variety) was higher in leaf and culm as compared to that of CPF 251 (low sucrose variety). In brief, this study adds to the present literature about sugarcane, sucrose metabolism and role of SPS in sucrose metabolism thereby opening up further avenues of research in crop improvement.