bluuebunny/crossref_metadata_2025 huggingface dataset:
Nghiên cứu đặc điểm một số biến thể gen microRNA-146a và mối liên quan với mức độ nặng lâm sàng của người bệnh nhồi máu cơ tim cấp
Authors: Toàn Ngô Hoàng , Sơn Trần Kim
Published: February 2025

MicroRNA-146a đóng vai trò quan trọng trong đáp ứng viêm và xơ hóa, các đa hình đơn nucleotide của gen này được báo cáo có liên quan đến mức độ nặng nhồi máu cơ tim cấp. Tuy nhiên, tại Việt Nam các nghiên cứu về vấn đề này còn hạn chế. Nghiên cứu tiến hành với mục tiêu: Khảo sát đặc điểm đa hình gen microRNA-146a và mối liên quan với mức độ nặng trên lâm sàng ở người bệnh nhồi máu cơ tim cấp. Mô tả cắt ngang 130 người bệnh nhồi máu cơ tim cấp có so sánh với nhóm chứng tại Bệnh viện Đa khoa Trung ương Cần Thơ và Bệnh viện Trường Đại học Y Dược Cần Thơ từ tháng 5/2023 đến tháng 11/2024. Tất cả người bệnh được khám lâm sàng và giải trình tự gen tìm đa hình rs2431697, rs57095329, rs2910164. Kết quả, nam giới chiếm 70,0%, tuổi trung bình 65,2 ± 11,0 tuổi. Nhóm bệnh có tỷ lệ kiểu gen TC + CC của đa hình rs2431697 cao hơn nhóm chứng, với 30,0% so với 19,2%. Tương tự, tỷ lệ kiểu gen CG + GG của đa hình rs2910164 ở nhóm bệnh cũng cao hơn nhóm chứng, 63,8% so với 48,5%. Alen C của đa hình rs2431697 (OR = 11,94), alen G của đa hình rs2910164 (OR = 5,81) gen microRNA-146a và rối loạn lipid máu (OR = 3,47) là các yếu tố độc lập làm tăng nguy cơ nhồi máu cơ tim cấp mức độ nặng trên lâm sàng. Bằng chứng trên cho thấy, alen nguy cơ C của rs2431697 và G của rs2910164 gen microRNA-146a cùng với rối loạn lipid máu là các yếu tố cần quan tâm vì làm tăng nguy cơ nhồi máu cơ tim mức độ nặng trên lâm sàng.
Đánh giá kết quả ngắn và trung hạn phẫu thuật hạ đại tràng qua hậu môn điều trị bệnh Hirschsprung tại Bệnh viện Nhi Đồng 1 - 2
Authors: Hoàng Trần Việt , Tuấn Hoàng Minh , Nhân Vũ Trường , Anh Huỳnh Thị Phương , Linh Trương Nguyễn Uy
Published: February 2025

Bệnh Hirschsprung là một bệnh lý bẩm sinh do sự vắng mặt của hạch thần kinh trong thành ruột. Phẫu thuật hạ đại tràng qua ngả hậu môn hiện là phương pháp điều trị tiêu chuẩn, nhưng vẫn còn tồn tại một số thách thức về biến chứng sau mổ. Chúng tôi thực hiện nghiên cứu tiến cứu ở 84 bệnh nhi (BN) được điều trị bằng phẫu thuật hạ đại tràng qua ngả hậu môn tại Bệnh viện Nhi Đồng 1 từ tháng 12/2022 đến tháng 6/2024 và Bệnh viện Nhi Đồng 2 từ 12/2023 đến 6/02024 nhằm đánh giá kết quả ngắn và trung hạn phương pháp này. Loại trừ những bệnh nhi mắc viêm ruột nặng phải mở hậu môn tạm. Biến số chính được nghiên cứu là biến chứng sau mổ và viêm ruột sau mổ 12 tháng. Độ tuổi trung bình là 7,2 ± 10,7 tháng (min: 1 tháng, max: 66 tháng), nam/nữ là 5,4/1. Phương pháp Swenson-like được áp dụng trong 66,6% trường hợp, với thời gian phẫu thuật trung bình 92,14 ± 33,8 phút (min: 45 phút, max: 160 phút). Tỷ lệ biến chứng viêm da quanh hậu môn là 32,1%, đặc biệt cao có ý nghĩa thống kê ở trẻ được phẫu thuật lúc 1 - 3 tháng tuổi (p < 0,05) và không liên quan đến phương pháp phẫu thuật (p = 0,051). Tỷ lệ hẹp miệng nối chiếm 6,1%. Táo bón xảy ra ở 14,4% trường hợp và viêm ruột sau mổ chiếm 16,7%, với nguy cơ tăng ở bệnh nhân có đoạn vô hạch dài. Phẫu thuật hạ đại tràng qua ngả hậu môn là phương pháp an toàn và hiệu quả trong điều trị bệnh Hirschsprung. Viêm da quanh hậu môn sau phẫu thuật thường gặp ở trẻ 1 - 3 tháng.
Bệnh tim mạch do xơ vữa và yếu tố nguy cơ ở người tăng cholesterol máu gia đình
Authors: Thanh Kim Ngọc , Hương Trương Thanh , Lợi Đỗ Doãn , Ngọc Nguyễn Thị Mai , An Lê Hồng , Tùng Lê Thanh
Published: February 2025

Nghiên cứu cắt ngang khảo sát đặc điểm yếu tố nguy cơ tim mạch và ảnh hưởng của các yếu tố này đến bệnh tim mạch (BTM) do xơ vữa với bệnh nhân tăng cholesterol máu gia đình (Familial hypercholesterolemia, FH), dựa trên phân tích dữ liệu 110 bệnh nhân FH tại Việt Nam. Kết quả nghiên cứu ghi nhận bệnh nhân được chẩn đoán FH ở độ tuổi trung bình 51,8 tuổi, với tỉ lệ mắc bệnh mạch vành (BMV) sớm là 35,5%. Tỉ lệ bệnh nhân có hút thuốc lá, thừa cân/béo phì, tăng huyết áp và đái tháo đường tương ứng là 43,6%, 43,6%, 37,3% và 5,5%. Trong đó, hút thuốc lá là yếu tố liên quan đến BMV và BMV sớm, với Odd Ratio tương ứng là 4,1 và 5,4. Tóm lại, nghiên cứu này ghi nhận bệnh nhân FH tại Việt Nam còn được chẩn đoán muộn, nhiều bệnh nhân đã có BTM do xơ vữa và có yếu tố nguy cơ tim mạch làm gia tăng gánh nặng xơ vữa. Điều này gợi ý cần thiết lập chương trình sàng lọc, chẩn đoán và can thiệp sớm FH tại Việt Nam.
Một số yếu tố liên quan đến năng lực lâm sàng của sinh viên điều dưỡng Trường Đại học Y Dược Cần Thơ năm 2024
Authors: Trúc Nguyễn Thị Thanh , Chi Lê Thị Kim , Trúc Mai Nguyễn Thanh , Thiệp Nguyễn Hồng , Nhàn Nguyễn Thị Thanh
Published: February 2025

Nghiên cứu thực hiện nhằm xác định mối liên quan giữa năng lực lâm sàng và một số đặc điểm của sinh viên điều dưỡng. Nghiên cứu mô tả cắt ngang thực hiện trên 98 sinh viên năm 3 và năm 4 tại Trường Đại học Y Dược Cần Thơ. Kết quả: Ghi nhận mối liên quan giữa năng lực lâm sàng của sinh viên điều dưỡng với năm học và sự tự tin trong học tập (p < 0,001). Trong đó, sinh viên học năm thứ 4 và tự tin trong học tập có năng lực lâm sàng tốt hơn nhóm sinh viên còn lại. Tuy nhiên, không ghi nhận sự liên quan giữa năng lực lâm sàng với giới tính và học lực (p > 0,05). Do đó, các đơn vị đào tạo cần tăng cường đào tạo thực hành tại bệnh viện và cơ sở y tế cho sinh viên từ năm thứ 3. Đồng thời, giảng viên cần xây dựng môi trường học tập thúc đẩy sự tự tin trong đó kết hợp chặt chẽ lý thuyết với thực hành để nâng cao năng lực lâm sàng của sinh viên điều dưỡng.
The Effect of Financial Management on Revenue for SME Actors in Gomo District South Nias, Indonesia
Authors: Hulu Ernamawati , Hulu Perlindungan F. , Bu’ulolo Nanny A. , Kakisina SophiaM.
Published: February 2025

From the observations, most SME actors in Gomo District, South Nias Regency still have minimal basic knowledge of good financial management. This is shown by the fact that most SME actors do not yet have financial reports, such as cash books, profit, and loss reports, and balance sheets, and have not saved for the future, invested, or taken out insurance, many of them still cannot separate personal finances from business finances. With this lack of knowledge of financial management, they cannot manage their expenses properly. Observations show that many SME actors often have difficulty reporting their financial position and calculating turnover, and business profits. The purpose of this study was to determine the Effect of Financial Management on Income for SME Actors in Gomo District, South Nias Regency. The population of this study was all Micro, Small, and Medium Enterprises in Gomo District, South Nias Regency. The results of the study showed that financial management had a significant effect on income.
Macroanatomical study on origin and distribution of Caucasian Lynx (Lynx lynx dinniki)’s the brachial plexus
Authors: Takcı Lutfi , Arı Hasan Hüseyin
Published: February 2025

This study aimed to determine the formation of the plexus brachialis, the nerves that ramify from the plexus, and their last branches in the Caucasian Lynx. It was found that the formation of the brachial plexus contributed to the ventral branches of the C6th, C7th, C8th, and T1th spinal nerves in the lynx. The ventral root of the C6th spinal nerve gave rise to the suprascapular nerve, the ventral of the C6th and C7th spinal nerve to the subscapular nerves and musculocutaneous nerve, the C7th to the cranial pectoral nerve, the C8th to the caudal pectoral nerve, the C8th and T1th to the lateral pectoral nerve, the radial nerve and the ulnar nerve, and the C7th, C8th, and T1th to the median nerve. The network formed by these branches was the origin of the cranial, caudal, long and lateral pectoral nerves, the suprascapular nerve to the extrinsic muscles of the scapula, the subscapular nerve to the intrinsic muscle of the scapula, the axillary nerve to the major teres and caudal portion of the subscapular muscle, the musculocutaneous nerve to the biceps muscle and its cutaneous, the radial nerve to the muscles of the forearm and pawn craniolateral aspect, the median nerve to the flexor digitorium superficial and profound muscles, and the ulnar nerve to the flexor ulnar carpi and the flexor deep digitorium muscle.
Pasión Tagala. Pinturas filipinas de 1813
Authors: Sierra de la Calle Blas
Published: February 2025

The research is concentrated in the study of 62 filipino paintings of the illuminated manuscript Pasión en verso Tagalo, done in 1813, that belong to the Library of the Real Colegio Seminario de los PP. Agustinos deValladolid, Spain.The topic is developed in six  chapters. In the first one is presented a summary of the evangelization of the Philippines. In the second and third, are studied the different rites and traditions of the Lent and Holy Week in the Philippine Islands through the centuries. Chapter four is dedicated to study the so called Pabasa or the rite of singing the Passion of Jesus, and the books about the life and passion of Jesus, used in this celebration. One of these books is the illuminated manuscript of Pasión en verso Tagalo studied in chapter five.Was written in 1813 in Bigaa, Philippines, and donated to the Library of the Augustinian Friars of Valladolid, by the Augustinian missionary Fr. Francisco M. Girón, in 1898. An attempt is made to know the author of the text, and the artist that did the paintings, probably one Spanish  Augustinian missionary. The sources of inspiration of the images represented, are mainly european engravings: the Bible of Nadal, the Catechism of Claude Fleury, and the works of art of many european artists (German, Flemish, Dutch, Italian, Spanish,  French). The 62 filipino paintings are studied in detail one by one, in chapter six, starting from the Creation of the World until the Last Judgement. Most of the works illustrate the life of the Virgin Mary, and the life of Jesus, specially the different moments of his Passion. In each one is proposed the source of inspiration. In the closing remarks is done one valuation of these extraordinary work of religious painting, unique in the Philippines. The study is completed with 65 colour illustrations, 62 of the paintings of 1813, and the other 3 related with the text.
INFLUENCE OF INDUSTRIAL WASTEWATER ON NATURAL SOIL: A REVIEW
Authors: Riya Desai , Pratik Patel
Published: February 2025

Waste disposal is a major concern due to rapid urbanization and industrialization. Finding cutting-edge, eco-friendly technology is urgently needed to tackle it. This paper reviews Constructed soil filter beds as engineered model design for wastewater treatment and evaluates the potential of using porous media, like soil rock, stone, gravel and plants in treating different industrial and domestic wastewater. Soil minerals and soil microorganism play important roles in elimination of pollutants from wastewater. This process removes BOD, COD, TSS, and TDS effectively, environment-friendly, cost-effective and in eco-friendly manner with general and natural mechanisms.
RELIGION AND PEACE: ANALYZING ISLAMIC APPROACH TO CONFLICT RESOLUTION
Authors: Maryam Dr. Binish
Published: February 2025

Religion has historically been crucial in influencing peacebuilding initiatives and conflict resolution methodologies. This paper examines the Islamic methodology for dispute resolution, highlighting its tenets of justice, reconciliation, and compassion. The research elucidates essential processes for dispute resolution, including mediation (ṣulḥ), arbitration (taḥkīm), and forgiveness (ʿafw), based on Islamic teachings from the Qur'an, Hadith, and classical jurisprudence. The study contends that Islamic teachings advocate for a comprehensive approach to peace, reconciling individual rights with social cohesion. This study enhances the comprehension of religion's role in promoting sustainable peace through the examination of theoretical frameworks and practical implementations.
Analisis Manajemen Risiko Aplikasi SRIKANDI Pada Kantor Diskominfo Kota Manado Menggunakan ISO 31000
Authors: Suawa Harvie Cartens Samuel , Chernovita Hanna Prillysca
Published: February 2025

Penelitian ini bertujuan untuk mengetahui hasil analisis manajemen resiko dengan menggunakan metode ISO 31000 pada aplikasi SRIKANDI dengan harapan dapat meminimalisir tingkat resiko pada penggunaan aplikasi SRIKANDI di Dinas Kominfo Pemerintah Kota Manado. Aplikasi SRIKANDI yaitu aplikasi yang digunakan untuk mempermudah kearsipan yang dapat mendukung pengelolaan arsip dan tata kelolah pemerintah berbasis elektronik. Beberapa tahapan yang sudah dilakukan antara lain tahap pengumpulan data, identifikasi resiko, analisis resiko, evaluasi resiko, dan perlakuan resiko. Berdasarkan hasil analisis yang dilakukan, hasil penelitian menunjukkan bahwa terdapat 23 kemungkinan resiko yang bisa saja terjadi dimana memiliki 13 kemungkinan resiko yang tinggi (High), 5 kemungkinan yang sedang (Medium), dan 5 kemungkinan resiko yang rendah (Low).
This study aims to determine the results of risk management analysis using the ISO 31000 method in the SRIKANDI application in the hope of minimizing the level of risk in using the SRIKANDI application at the Manado City Government Communication and Information Office. The SRIKANDI application is an application used to facilitate archives that can support electronic-based archive management and government governance. Some of the stages that have been carried out include the stages of data collection, risk identification, risk analysis, risk evaluation, and risk treatment. Based on the results of the analysis conducted, the results showed that there are 23 possible risks that could occur which have 13 high-risk possibilities (High), 5 medium possibilities (Medium), and 5 low-risk possibilities (Low).
Pengaruh Media Pembelajaran Berbasis Teknologi Terhadap Minat Belajar Siswa di SMK N 5 Manado
Authors: Bate’e Zelita , Palilingan Verry Ronny , Mewengkang Alfrina
Published: February 2025

ABSTRAK
Penelitian ini bertujuan untuk mengetahui pengaruh media pembelajaran berbasis teknologi terhadap minat belajar siswa di SMK N 5 Manado. Penelitian ini merupakan penelitian kuantitatif dengan jenis metode korelasional. Populasi dalam penelitian ini adalah seluruh siswa di SMKN 5 Manado, dan sampel berjumlah 70 orang. Teknik pengumpulan data menggunakan kuesioner, wawancara, observasi dan dokumentasi. Uji instrument dilakukan dengan uji validitas dan reliabilitas. Uji prasyarat yang dipakai dalam penelitian ini adalah uji normalitas dan uji linearitas. Sedangkan uji hipotesis yang dipakai yaitu uji regresi sederhana, korelasi sederhana, uji t dan koefisien determinasi. Hasil penelitian ini menunjukkan bahwa media pembelajaran berbasis teknologi berpengaruh terhadap minat belajar siswa di SMKN 5 Manado sebesar 52 % dan sisanya 48% dipengaruhi oleh variabel yang tidak diteliti.
ABSTRACT
 This study aims to determine the influence of technology-based learning media on student learning interests at SMK N 5 Manado. This research is a quantitative study using a correlational method. The population of this study comprises all students at SMKN 5 Manado, with a sample size of 70 individuals. Data collection techniques include questionnaires, interviews, observations, and documentation. Instrument testing was conducted through validity and reliability tests. The prerequisite tests used in this study are the normality test and linearity test. Meanwhile, the hypothesis tests employed include simple regression analysis, simple correlation, t-test, and the coefficient of determination. The results of this study indicate that technology-based learning media have an impact on student learning interest at SMKN 5 Manado by 52%, with the remaining 48% influenced by variables not examined in this study.
Pengembangan Media Pembelajaran TIK Berbasis Mobile di Kelas X SMAN 1 Lembean Timur
Authors: Ponto Fenny Kristanti , Pardanus Rudy Harijadi Wibowo , Palilingan Verry Ronny
Published: February 2025

ABSTRAK
Tujuan dilakukan penelitian ini untuk mengembangkan media pembelajaran pada mata pelajaran Teknologi Informasi dan Komunikasi (TIK) berbasis Mobile di Kelas X SMAN 1 Lembean Timur serta memperoleh tingkat kelayakan media pembelajaran. Penelitian ini menggunakan metode Research and Development dengan menggunakan prosedur penelitian dari Sutopo yang lebih dikenal Multimedia Development Life Cycle. Hasil Penelitian ini adalah Berhasil mengembangkangkan media pembelajaran mata pelajaran Teknologi Informasi dan Komunikasi (TIK) dan tingkat kelayakan media pembelajaran ini diuji dengan usability testing yang mana media dapat berjalan di berbagai sistem operasi android, usability testing dengan memperoleh nilai 94.2% dengan kriteria sangat layak dinilai oleh siswa, validator media memberi skor 90,47% dengan kriteria sangat layak yang dinilai oleh Dosen PTIK, dan validator materi memberi skor 97,58% dengan kriteria sangat layak. Sehingga dapat disimpulkan media pembelajaran ini sudah layak untuk digunakan sebagai media pembelajaran pada mata pelajaran Teknologi Informasi dan Komunikasi (TIK).
ABSTRACT
 This research aimed to develop learning media for Mobile-based Information and Communication Technology (ICT) subjects in Class This research uses the Research and Development method using Sutopo's research procedure, better known as the Multimedia Development Life Cycle. The results of this research are: Successfully developing learning media for Information and Communication Technology (ICT) subjects and the level of feasibility of this learning media was tested with usability testing where the media can run on various Android operating systems, usability testing obtained a score of 94.2% with the criteria being very worthy of being assessed. by students, the media validator gave a score of 90.47% with very decent criteria as assessed by PTIK Lecturers, and the material validator gave a score of 97.58% with very decent criteria. So it can be concluded that this learning media is suitable for use as learning media in Information and Communication Technology (ICT) subjects.
Pengembangan Video Pembelajaran Informatika di SMK
Authors: Kamagi Frisco Aldo , Wonggo Djafar , Liando Olivia Eunike Selvie
Published: February 2025

ABSTRAK
Penelitian ini bertujuan untuk membuat rancangan video pembelajaran yang dipakai untuk mendukung kegiatan dalam proses belajar mengajar pada mata pelajaran informatika di SMK Negeri 1 Tondano. Penelitian ini menerapkan metode Research & Development dengan menggunakan model pengembangan Analysys Design Development Implementatition Evaluate (ADDIE). Model ini terbagi dalam lima tahapan antara lain, Analys, design, Development, Implementation. Setelah di uji validitas oleh ahli materi, ahli media, guru multimedia dan selanjutnya untuk tahap uji coba produk. Proses uji coba produk melibatkan siswa – siswi kelas 10 Desain Komunikasi Visual (DKV) yang berjumlah 30 peserta, pengujian uji coba dilakukan di SMK Negeri 1 Tondano. Pendekatan analisis yang di pakai adalah metode kualitatif dan metode kuantitatif untuk menilai seberapa layak media pembelajaran yang dihasilkan. Penelitian menunjukkan hasil, yaitu a) menciptakan video pembelajaran yang akan digunakan oleh siswa kelas 10 SMK Negeri 1 Tondano untuk mata pelajaran informatika, b) tingkat kelayakan dari video pembelajaran berdasarkan ahli media dengan skor 92 atau sangat layak, ahli materi dengan skor 92 atau sangat layak, Guru multimedia dengan skor 90 atau sangat layak serta hasil uji coba produk pada siswa memenuhi syarat sangat layak dengan nilai rata-rata 89,6 pada pembelajaran siswa kelas 10 SMK Negeri 1 Tondano.
ABSTRACT
 This research aims to create a learning video design that is used to support activities in the teaching and learning process in informatics subjects at SMK Negeri 1 Tondano. This research applies the Research & Development method using the Analysis Design Development Implementation Evaluate (ADDIE) development model. This model is divided into five stages, including, Analysis, design, Development, Implementation. After validity testing by material experts, media experts, multimedia teachers and then on to the product trial stage. The product testing process involved 30 students of class 10 Visual Communication Design (DKV), the trial testing was carried out at SMK Negeri 1 Tondano. The analytical approach used is a qualitative method and a quantitative method to assess how appropriate the resulting learning media is. The research shows the results, namely a) creating a learning video that will be used by class 10 students of SMK Negeri 1 Tondano for informatics subjects, b) the level of feasibility of the learning video based on media experts with a score of 92 or very decent, material experts with a score of 92 or very worthy, a multimedia teacher with a score of 90 or very worthy and the results of product trials on students meet the requirements of very worthy with an average score of 89.6 in class 10 student learning at SMK Negeri 1 Tondano.
Sistem Informasi Manajemen Indikator Kinerja Utama 1 Berbasis Web di Universitas Negeri Manado
Authors: Mewengkang Alfrina , Manoppo Christine Takarina Meitty , Runtuwene Efraim Refival
Published: February 2025

ABSTRAK
Perguruan tinggi pasti membutuhkan informasi tentang alumninya mengenai jurusan, tahun kelulusan, tempat kerja, dan beberapa informasi lainnya. Dalam universitas proses ini dinamakan Indikator Kinerja Utama 1 (IKU 1) atau proses pelacakan terhadap alumni. Dengan IKU 1 Universitas bisa mengukur dan melacak kinerja Alumni sehingga bisa di dapati indikator yang jelas. Universitas Negeri Manado belum memiliki sistem yang dapat memudahkan proses pengolahan dan penelusuran data alumni. Oleh karena itu dikembangkan suatu sistem informasi Manajemen Idikator Kinerja Utama 1 yang dapat menampung dan mengelolah data dari para alumni universitas negeri manado. Selama proses pengembangan sistem, metode yang di pakai yaitu metode extreme programming dengan menggunakan pemodelan bahasa Unified Modeling Language atau biasanya di sebut sebagai (UML). Penggunaan bahasa pemrograman Go-lang dalam implementasi dan menggunakan Library React JS dari Javascript. Penelitian ini akan menghasilkan sistem informasi Manajemen Idikator Kinerja Utama 1 yang diharapkan dapat membantu universitas mengumpulkan, mengelola, dan mencari data alumni.
ABSTRACT
 Universities definitely need information about their alumni regarding their majors, graduation years, workplaces, and some other information. In universities, this process is called Key Performance Indicator 1 (KPI 1) or the alumni tracking process. With KPI 1, universities can measure and track alumni performance so that clear indicators can be obtained. Manado State University does not yet have a system that can facilitate the process of processing and tracking alumni data. Therefore, a Key Performance Indicator Management information system 1 was developed that can accommodate and manage data from alumni of Manado State University. During the system development process, the method used was the extreme programming method using the Unified Modeling Language or usually referred to as (UML). The use of the Go-lang programming language in the implementation and using the React JS Library from Javascript. This research will produce a Key Performance Indicator Management information system 1 which is expected to help universities collect, manage, and search for alumni data.
Pengembangan Sistem Informasi Pencapaian Indikator Kinerja Utama 2 di Universitas Negeri Manado
Authors: Mewengkang Alfrina , Rianto Indra , Kalalo Marvell Lambert
Published: February 2025

ABSTRAK
Perguruan tinggi dituntut untuk dapat lebih fokus mencapai tujuan kinerja karena selaku lembaga ilmu, pengetahuan, penelitian serta pengabdian terhadap masyarakat. Salah satu kunci untuk mengatur kinerja ialah dengan Indikator Kinerja Utama. Akan tetapi Universitas Negeri Manado belum adanya sistem informasi untuk menginput dan mengelola IKU terlebih khusus IKU 2 masih menggunakan aplikasi web Google Form, dalam hal ini IKU 2 untuk mengatur kegiatan mahasiswa di luar kampus dan prestasinya. Oleh karena itu penelitian dilakukan agar supaya dapat mengembangkan sistem informasi pencapaian Indikator Kinerja Utama 2 untuk mempermudah Univeristas Negeri Manado dalam menginput dan mengelola data IKU 2. Metode yang digunakan untuk membangun sistem informasi IKU 2 yaitu Extreme Programming dan digunkannya pemodelan Unified Modeling Language (UML) agar dapat lebih mempermudah untuk merancang sistem yang akan dibuat. Bahasa program yang akan digunakan untuk membangun Back-end yaitu menggunakan Go-lang dan Front-end menggunakan Library React JS dari Javascript. Metode pengujian yang akan digunakan terhadap sistem adalah dengan menggunakan Black-box, dengan hasil dari pengujian Black-box yang dilakukan mengeluarkan valid, sistem tersebut berjalan sesuai dengan diharapkan.
ABSTRACT
Universities are required to be able to focus more on achieving performance goals because they are institutions of science, knowledge, research and community service. One of the keys to managing performance is with Key Performance Indicators. However, Manado State University does not yet have an information system to input and manage IKU, especially specifically IKU 2, still using the Google Form web application, in this case IKU 2 to regulate student activities outside campus and their achievements. Therefore, research was conducted in order to develop an information system for achieving Key Performance Indicator 2 to make it easier for Manado State University to input and manage IKU 2 data. The method used to build the IKU 2 information system is Extreme Programming and the use of Unified Modeling Language (UML) modeling to make it easier to design the system to be created. The programming language that will be used to build the Back-end is using Go-lang and the Front-end uses the React JS Library from Javascript. The testing method that will be used for the system is to use Black-box, with the results of the Black-box testing carried out issuing valid, the system runs as expected.
Pengaruh Model Pembelajaran Problem Based Learning Terhadap Hasil Belajar Teknologi Layanan Jaringan Siswa Kelas XI TKJ SMK Negeri 1 Mopuya
Authors: Yasa Made Kerty , Palilingan Verry Ronny , Mewengkang Alfrina
Published: February 2025

ABSTRAK
Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan model pembelajaran Problem Based Learnig terhadap hasil belajar Teknologi Layanan Jaringan siswa kelas XI SMK Negeri 1 Mopuya. Metode penelitian ini menggunakan metode kuantitatif yaitu quasi experimental design. Peneliti mengumpulkan data yang diambil menggunakan soal tes pilihan ganda 30 nomor. Selanjutnya peneliti menganalisis dan mengolah data. Uji normalitas untuk kedua kelas berdistribusi normal dan uji homogenitas untuk kelas post-test adalah homogen. Uji validitas mendapatkan 25 soal valid dan hasil dari uji reliabilitas soal adalah reliabel. Kesimpulan yang diperoleh adalah terdapat pengaruh penggunaan model pembelajaran Problem Based Learnig terhadap hasil belajar Teknologi Layanan Jaringan siswa kelas XI TKJ di SMK Negeri 1 Mopuya.
 ABSTRACT
 This research aims to determine the effect of using the Problem-Based Learning model on the Network Service Technology learning outcomes of class XI students at SMK Negeri 1 Mopuya. This research method uses a quantitative method, namely quasi quasi-experimental design. Researchers collected data using 30 number multiple-choice test questions. Next, researchers analyzed and processed the data. The normality test for both classes is normally distributed and the homogeneity test for the post-test class is homogeneous. The validity test found 25 valid questions and the results of the question reliability test were reliable. The conclusion obtained is that there is an influence of the use of the Problem-Based Learning model on the Network Service Technology learning outcomes of class XI TKJ students at SMK Negeri 1 Mopuya.
Game Edukasi pembelajaran Lagu Nasional dan Daerah
Authors: Mewengkang Alfrina , Heydemans Charnila Desria , Lampus Emelia Rut
Published: February 2025

ABSTRAK
Tujuan dari penelitian ini dapat membangun game edukasi pembelajaran lagu nasional dan daerah yang dapat digunakan sebagai alat bantu dalam menyampaikan informasi tentang lagu nasional dan daerah. Metode pengembangan pada penelitian ini menggunakan metode pengembangan Multimedia Development Live Cycle (MDLC). pembuatan aplikasi yang sesuai dengan konsep maka peneliti memperoleh hasil dari penelitian aplikasi game edukasi pembelajaran lagu nasional dan daerah, maka diperoleh hasil pada tahap ini sebagai evaluasi apakah aplikasi ini telah siap digunakan untuk mengedukasi anak-anak dalam game edukasi pembelajaran lagu nasional dan daerah sebagai media pembelajaran yang baru.
ABSTRACT
The purpose of this study is to build an educational game for learning national and regional songs that can be used as a tool in conveying information about national and regional songs. The development method in this study uses the Multimedia Development Live Cycle (MDLC) development method. making an application that is in accordance with the concept, the researcher obtains the results of the research on educational game applications for learning national and regional songs, then the results obtained at this stage as an evaluation of whether this application is ready to be used to educate children in educational games for learning national and regional songs as a new learning medium.
Analisis Manajemen Resiko Aplikasi INLIS LITE pada Perpustakaan Kantor DPRD Kota Salatiga Menggunakan Failure Mode and Effects Analysis (FMEA)
Authors: Engka Akwila , Sitokdana Melkior
Published: February 2025

ABSTRAK
Aplikasi INLIS LITE adalah aplikasi yang dikembangkan dan dibangun secara resmi oleh Perpustakaan Nasional Republik Indonesia. Aplikasi ini digunakan untuk membantu proses kegiatan pengelolaan bahan Pustaka di Perpustakaan, namun tidak dapat dipungkiri Aplikasi Inlis Lite pasti memiliki kemungkinan permasalahan yang akan mengganggu fungsi dari pada aplikasi tersebut. Dalam menggunakan teknologi informasi maka digunakan metode Failure Mode & Effect Analysis (FMEA) pada Perpustakaan Kantor DPRD Kota Salatiga yang bertujuan untuk menganalisis risiko yang dihadapi dan langkah-langkah yang diambil untuk meminimalkan risiko. Dari hasil penelitian di dapatkan bahwa terdapat 22 penyebab kegagalan terdapat 1 aktivitas kategori High (Tinggi), 17 aktivitas kategori Low (Rendah) dan 4 dengan kategori Very Low (Sangat Rendah).
 ABSTRACT
 The INLIS LITE application is officially developed by the National Library of the Republic of Indonesia. While it aids in the management of library materials, it is acknowledged that the application may encounter potential issues. To address this, Information Technology utilizes the Failure Mode and Effect Analysis (FMEA) method at the Library of the City DPRD Salatiga, aiming to analyze risks and implement measures to minimize them. The research revealed 22 failure causes, with 1 falling into the High category, 17 in the Low category, and 4 in the Very Low category.
Perancangan Aplikasi Obyek Wisata Berbasis Mobile di Likupang Minahasa Utara
Authors: Najoan Patrick , Widiasari Indrastanti
Published: February 2025

ABSTRAK
Penelitian ini bertujuan untuk merancang aplikasi mobile yang menyediakan panduan komprehensif tentang destinasi wisata di Likupang, Minahasa Utara, yang telah diakui sebagai salah satu dari lima destinasi super prioritas di Indonesia oleh Kementerian Pariwisata dan Ekonomi Kreatif. Aplikasi ini bertujuan untuk memberikan informasi akurat dan berguna mengenai objek wisata teratas di Likupang, termasuk ulasan, peringkat pengunjung, dan navigasi terintegrasi melalui peta interaktif yang terhubung dengan Google Maps. Penelitian ini menggunakan metode waterfall yang meliputi tahap analisis kebutuhan, perancangan, implementasi, dan pengujian. Hasil penelitian menunjukkan bahwa aplikasi yang dirancang mampu memberikan kemudahan bagi wisatawan dalam merencanakan perjalanan mereka, meningkatkan pengalaman wisata, serta berpotensi memberikan dampak positif bagi perekonomian lokal dan kelestarian lingkungan. Kajian terhadap penelitian terdahulu menunjukkan pentingnya penggunaan teknologi digital dalam memaksimalkan potensi pariwisata dan mengoptimalkan pengalaman pengguna. Hasil penelitian menunjukan bahwa pengguna menyatakan puas terhadap aplikasi “Manjo ke Likupang” dengan skor skala likert sebesar 4.01. Penelitian ini membuktikan bahwa masyarakat Indonesia membutuhkan aplikasi untuk melihat rating destinasi wisata yang ingin dituju.
ABSTRACT
 This study aims to design a mobile application that provides a comprehensive guide to tourist destinations in Likupang, North Minahasa, which has been recognized as one of the five super-priority destinations in Indonesia by the Ministry of Tourism and Creative Economy. The application aims to provide accurate and useful information about the top tourist attractions in Likupang, including reviews, visitor ratings, and integrated navigation through interactive maps connected to Google Maps. This study employs the waterfall method, which includes the stages of requirement analysis, design, implementation, and testing. The results indicate that the designed application can facilitate tourists in planning their trips, enhance their travel experience, and potentially have a positive impact on the local economy and environmental sustainability. A review of previous studies highlights the importance of digital technology in maximizing tourism potential and optimizing user experience. The study's findings show that users are satisfied with the "Manjo ke Likupang" application, with a Likert scale score of 4.01. This research demonstrates that Indonesians need an application to view ratings of the tourist destinations they intend to visit.
Studi Netnografi: Respon Penonton dalam Tayangan “Hilang dalam Dekapam Semeru” pada Channel Youtube RJL 5
Authors: Maulana Zidan Abid , Mustain Mustain
Published: February 2025

ABSTRAK
Jumlah pengguna YouTube di Indonesia sendiri tercatat sebanyak 88,16 persen dari total pengguna internet. Ini menunjukkan bahwa YouTube merupakan platform video online dengan penetrasi tinggi di Indonesia. Penelitian ini bertujuan untuk menganalisis respon penonton terhadap video "Hilang Dalam Dekapan Semeru" pada channel YouTube RJL 5 dengan menggunakan metode netnografi. Video tersebut menceritakan kisah nyata tentang kehilangan teman saat mendaki Gunung Semeru. Metode penelitian yang digunakan adalah kualitatif dengan pendekatan netnografi untuk mempelajari interaksi sosial dan respon penonton secara online. Data diperoleh dari komentar publik pada video yang menjadi objek penelitian. Hasilnya menunjukkan banyak respon positif yang menganggap video tersebut memberikan pelajaran hidup dan motivasi. Selain itu video ini dinilai mampu memberikan hiburan serta inspirasi bagi penontonnya. Hasil dari penelitian ini adalah bahwa konten horor di YouTube tidak selalu identik dengan hal-hal negatif seperti unsur SARA, pornografi, ataupun hoaks. Video "Hilang Dalam Dekapan Semeru" justru mampu memberikan manfaat positif bagi penontonnya. Hasil penelitian ini diharapkan dapat meningkatkan kualitas konten serta optimalisasi platform YouTube.
 ABSTRACT
 The number of YouTube users in Indonesia itself is recorded at 88.16 percent of total internet users. This shows that YouTube is an online video platform with high penetration in Indonesia. This study aims to analyze the audience response to the "Lost in Semeru's Embrace" video on the RJL 5 YouTube channel using the netnography method. The video tells a true story about losing friends while hiking Mount Semeru. The research method used is qualitative with a netnographic approach to study social interactions and audience responses online. Data were obtained from public comments on the video under study. The results show many positive responses that consider the video provides life lessons and motivation. In addition, this video is considered to provide entertainment and inspiration for the audience. The result of this research is that horror content on YouTube is not always identical with negative things such as SARA elements, pornography, or hoaxes. The "Lost in Semeru's Embrace" video is actually able to provide positive benefits for the audience. The results of this study are expected to improve content quality and optimization of the YouTube platform.
Variantes de hemoglobina en pacientes con anemia en el hospital Carlos Centeno, Siuna, Nicaragua
Authors: Martínez Arauz Emérita , Ortega Valdés Ligia Lorena
Published: February 2025

La hemoglobina humana puede presentar alteraciones conocidas como hemoglobinopatías, ocasionadas por trastornos hereditarios autosómicos. Las variantes de la hemoglobina pueden ser de dos tipos: cualitativas o estructurales y cuantitativas, estas son cada vez más frecuentes en la población como consecuencia del aumento de las corrientes migratorias de los seres humanos. La cromatografía líquida de alta resolución (HPLC) es el método utilizado para la separación de hemoglobinas en este estudio, dado que tiene la capacidad de detectar algunas variantes de hemoglobina, entre las principales estan HbE, HbD, HbS, y HbC. El objetivo de esta investigación se centra en el grupo étnico y en la detección de variantes de hemoglobinas en pacientes con anemia, siendo de mucho interés sanitario ya que se debe mantener y cuidar la salud de los grupos étnicos. El área de estudio fue en el Hospital Carlos Centeno de Siuna, ubicado en la Costa Caribe Norte, a 318 km de la capital de Nicaragua, Managua. El estudio se desarrolló con 67 pacientes con anemia de todas las edades y de ambos sexos. En los resultados se encontró que el sexopredominante fue el femenino con el 63%, el rango de edad que más destaca fue de 11-15 años con el 12%, el 75% de los pacientes son de etnia Mestizo, el 12% de etnia Mayangna, el 7% de etnia Miskitu y el 6% de etnia Creoles. El 81% de los pacientes con anemia no tienen diagnóstico de ninguna hemoglobinopatía S y un 19% de los pacientes con diagnóstico de anemia obedece a la presencia de hemoglobinopatías por HPLC.
Intervenções psicossociais para a promoção da saúde mental de estudantes do ensino superior: uma revisão sistemática de literatura
Authors: Marques Esther de Matos Ireno , Francklin Luma Leitão , Santos Maíra Aparecida dos , Santos Fabiane Rossi dos
Published: February 2025

A literatura apresenta um aumento significativo de pesquisas acerca do impacto de diversas modalidades de intervenção na saúde mental de estudantes do ensino superior. No entanto, a despeito dos estudos encontrados, faz-se necessária a condução de investigações que sintetizem as evidências disponíveis sobre a eficácia dessas intervenções. Partindo da importância dos profissionais de Saúde e Educação basearem suas práticas em indicadores científicos, o objetivo do presente estudo é identificar na literatura as modalidades de intervenção que têm sido propostas com essa finalidade, as características dos estudos realizados sobre o tema e os resultados alcançados. A fim de buscar as melhores fontes de evidências, conduziu-se uma pesquisa de revisão sistemática de literatura a partir de trabalhos publicados em inglês, português ou espanhol nos últimos cinco anos. Baseando-se no Protocolo Prisma, realizou-se a busca de artigos que versavam sobre o objeto da pesquisa, sendo selecionados 27 trabalhos para análise. Os dados apontam a existência de uma variedade de intervenções com resultados promissores. Entretanto, são necessários estudos com maior robustez metodológica, que comparem diferentes intervenções e que analisem o impacto dessas em grupos de diferentes características acadêmicas e sociodemográficas. Além de apresentar um panorama geral do campo de estudos das intervenções voltadas para a promoção da saúde mental de estudantes do ensino superior, este trabalho aponta as principais lacunas e direcionamentos para uma agenda futura de pesquisas.
Validação de conteúdo de Escala de Estratégias de Aprendizagem para o Ensino Médio (EEATDIC-EM)
Authors: Galvão Angela de Souza Lopes , Mombelli Monica Augusta
Published: February 2025

Este estudo teve como objetivo desenvolver e validar um instrumento para mensurar o uso de estratégias de aprendizagem cognitivas e metacognitivas, mediadas ou não por Tecnologias Digitais de Informação e Comunicação, para estudantes do Ensino Médio. A pesquisa foi conduzida em três etapas: a) revisão da literatura e levantamento de dados com alunos, que responderam a um questionário de 28 itens; b) elaboração dos itens do instrumento; c) validação de conteúdo com experts, especialistas e público-alvo. Os dados foram analisados utilizando o Coeficiente de Validade de Conteúdo (CVC). O questionário foi respondido por 191 alunos e, a partir da análise dos dados teóricos e empíricos, foi elaborado o instrumento "Escala de Estratégias de Aprendizagem com opção de Tecnologias Digitais para o Ensino Médio (EEATDIC-EM)", composto por 41 itens. A validação de conteúdo contou com a participação de cinco experts, dois especialistas e 30 adolescentes, e os resultados mostraram elevados índices de validade (CVC de 0,98 para clareza, 0,96 para pertinência e 0,93 para abrangência). Espera-se que o instrumento seja útil para identificar estratégias de aprendizagem e apoiar a criação de intervenções pedagógicas, promovendo o uso consciente de tecnologias digitais e o desenvolvimento de habilidades como autonomia, autorregulação e pensamento crítico, contribuindo para o aprimoramento do desempenho acadêmico.
Inteligência artificial e literacia digital: percepções de egressos do PROFEI/UNEMAT/Sinop e do PPGDiver/FEEVALE/RS sobre práticas pedagógicas inclusivas no contexto educativo contemporâneo
Authors: Brugnera Elisângela Dias , Barbosa Debora Nice Ferrari
Published: February 2025

Este estudo se propõe a investigar as percepções de docentes egressos dos programas de pós-graduação stricto sensu dos PROFEI (UNEMAT) e PPGDiver (FEEVALE) acerca da integração da inteligência artificial (IA) em práticas pedagógicas no contexto educacional contemporâneo, bem como o impacto dessa integração na literacia digital dos alunos. Metodologicamente, optou-se por uma abordagem qualitativa, utilizando-se o delineamento de estudo de caso coletivo, para analisar as percepções de um universo amostral composto por 30 docentes egressos dos programas mencionados (17 do PROFEI e 13 do PPGDiver), selecionados mediante adesão voluntária. A coleta de dados foi realizada por meio de um questionário semiestruturado, aplicado virtualmente via plataforma Google Forms, que explorou as seguintes dimensões: percepções sobre a IA em práticas pedagógicas; compreensão e aplicação da literacia digital; e desafios na integração da IA no contexto educacional. A análise dos dados se fundamentou na técnica de análise de conteúdo proposta por Laurence Bardin (2020), com o auxílio do software IRaMuTeQ para análise de dados qualitativos. Os achados apontam para um reconhecimento significativo da importância da IA no contexto educacional, com destaque para a personalização do ensino e o desenvolvimento de recursos educativos específicos. Entretanto, a pesquisa também revelou lacunas significativas na formação docente em relação à utilização da IA e ao desenvolvimento da literacia digital, indicando a necessidade de programas de formação continuada mais robustos e alinhados com as demandas contemporâneas.
Neurociência e metodologias ativas no ensino de língua inglesa: a sala de aula invertida como estratégia de aprendizagem
Authors: Cavalcante Luciana Rocha , Thompson Jackeline Lourene do Sacramento , Garcez Deniane de Araújo , Gonçalves Alan Sérgio
Published: February 2025

Durante as últimas décadas, a investigação em neurociências tem revelado eventos que ocorrem ao nível do funcionamento cerebral e que afetam diretamente o processamento e a consolidação da aprendizagem. Esses avanços trouxeram novas perspectivas sobre como o cérebro humano se desenvolve em ambientes educacionais, abrindo caminho para práticas pedagógicas mais eficazes. Nessa perspectiva, as contribuições da neurociência são apresentadas neste trabalho por meio de uma revisão documental, informativa e analítica sobre a aplicação da neurociência no ensino e aprendizagem da língua inglesa como língua franca, utilizando metodologias ativas, tal como a sala de aula invertida. O postulado sobre a orientação natural do cérebro para aprender é analisado detalhadamente, buscando compreender como o cérebro processa a aprendizagem em interação com um ambiente enriquecido por vias multissensoriais e experiências significativas. Além disso, destaca-se a relevância da adaptação das práticas pedagógicas às descobertas neurocientíficas, especialmente no ensino de línguas, com o intuito de promover uma aprendizagem mais eficiente e significativa. Concebe-se, dessa forma, a necessidade de fornecer novas explicações e perspectivas que possam orientar e aprimorar a prática docente dos professores, capacitando-os a atuar de maneira mais alinhada às particularidades neurocognitivas dos estudantes em seus próprios contextos educacionais.
Extremos climáticos de chuva (1990 a 2020) em três cidades do Norte do Brasil
Authors: Alves Anna Raisa da Costa , Sousa Maurício Dumont Ferreira de , Oliveira Leidiane Leão de
Published: February 2025

Importantes consequências das mudanças climáticas são as ocorrências de secas ou do aumento na intensidade das chuvas em várias regiões do globo terrestre, que pode reduzir ou aumentar a disponibilidade de água no sistema e afeta diretamente o homem e podem estar relacionados com a atuação de fenômenos atmosféricos como El Niño (La Niña). Na Amazônia os impactos dos eventos extremos ocorreram na intensidade, frequência e duração das secas e cheias. Este trabalho teve como objetivo analisar eventos extremos de precipitação e o índice de anomalia de chuvas – ICA para o período de 1991 a 2020 em três municípios da região Norte. Para classificar a magnitude dos eventos extremos de precipitação, como positivos ou negativos, foi utilizado o Índice de Anomalia de Chuvas (IAC). Belém apresentou um aumento da tendência de chuvas, enquanto, Belterra e Macapá houve diminuição das chuvas mensais e anuais, para os 30 anos analisados. Com relação aos Índices de Anomalias de Chuva (IAC), somente El Niños extremos, tais como os de 1992, 1998, 2003 e 2015, apresentaram redução na precipitação em todas as três localidades, enquanto o La Niña de 2000, 2005, 2006, 2009 e 2011, apresentaram os maiores aumentos em precipitação em Belém-PA, Belterra-PA e Macapá-AP. O IAC aplicado neste estudo foi um bom indicador de extremos climáticos regionais por município. Estudos como este são fundamentais para propostas e decisões mais assertivas dos gestores locais, regionais e estaduais.
Transformation and Challenges of Teachers' Roles in the Digital Media Age
Authors: Meng Xiang
Published: February 2025

With the rapid development of digital media, great changes have taken place in the mode of education, but also for the majority of educators to provide new opportunities and challenges. In the digital media environment, teachers should not only play a role of simply imparting knowledge, but also play an active role. This change has changed the traditional way of education, requiring teachers to integrate a variety of digital media into their educational strategies. This requires English teachers to strengthen their digital quality education and adopt creative education methods to meet the growing diversity of learning needs. But there are also problems with digital teaching, such as getting students to participate actively, giving them equal access to technology, and taking into account users' privacy and security. This article discusses the role of teachers in the age of digital media, the impact of technological integration on educational practice, and how educators can flourish in this digital society. On the basis of consulting relevant materials and case studies, this paper makes a deep discussion on how to improve the teaching effect and create a good learning atmosphere.