bluuebunny/crossref_metadata_2025 huggingface dataset:
Safety and Efficacy of Intravenous Thrombolysis in the 3- to 4.5-hour Window in Acute Ischemic Stroke Patients Who Have Both Diabetes Mellitus and History of Prior Stroke
Authors: Kim Boyoung , Lee Ji Sung , Park Hong-Kyun , Yung Young Bok , Oh Ki Chang , Park Jeong Joo , Cho Yong-Jin , Kang Kyusik , Lee Soo Joo , Kim Jae Guk , Cha Jae-Kwan , Kim Dae-Hyun , Bae Hee-Joon , Park Tai Hwan , Park Sang-Soon , Lee Kyung Bok , Lee Jun , Lee Byung-Chul , Lee Minwoo , Kim Joon-Tae , Choi Kang-Ho , Kim Dong-Eog , Choi Jay Chol , Shin Dong-Ick , Kwon Jee-Hyun , Kim Wook-Joo , Sohn Sung Il , Hong Jeong-Ho , Park Hyung Jong , Jang Seong-Hwa , Park Kwang-Yeol , Lee Sang-Hwa , Park Jong-Moo , Hong Keun-Sik
Published: May 2023

Background: For acute ischemic stroke (AIS) patients with history of prior stroke (PS) and diabetes mellitus (DM), intravenous recombinant tissue plasminogen activator (IV-tPA) therapy in the 3- to 4.5-hour window is off-label in Korea. This study aimed to assess the safety and efficacy of IV-tPA in these patients.Methods: Using data from a prospective multicenter stroke registry between January 2009 and March 2021, we identified AIS patients who received IV-tPA in the 3- to 4.5-hour window, and compared the outcomes of symptomatic intracranial hemorrhage (SICH), 3-month mortality, 3-month modified Rankin Scale (mRS) score 0-1 and 3-month mRS distribution between patients with both PS and DM (PS/DM, n=56) versus those with neither PS nor DM, or with only one (non-PS/DM, n=927).Results: The PS/DM group versus the non-PS/DM group was more likely to have a prior disability, hypertension, hyperlipidemia, coronary heart disease and less likely to have atrial fibrillation. The PS/DM and the non-PS/DM groups had comparable rates of SICH (0% vs. 1.7%; p>0.999) and 3-month mortality (10.7% vs. 10.2%; p=0.9112). The rate of 3-month mRS 0-1 was non-significantly lower in the PS/DM group than in the non-PS/DM group (30.4% vs. 40.7%; adjusted odds ratio [95% confidence interval], 0.81 [0.41-1.59]).Conclusions: In the 3- to 4.5-hour window, AIS patients with PS/DM, as compared to those with non-PS/DM, might benefit less from IV-tPA. However, given the similar risks of SICH and mortality, IV-tPA in the late time window could be considered in patients with both PS and DM.
Decision-making Approach in Late-onset Bilateral Semantic Variant Primary Progressive Aphasia with Coexisting Asymmetric Regional Amyloid Deposition
Authors: Oh Ki Chang , Park Jeong Ju , Yung Young Bok , Kim Bo Young , Kim Ji Eun
Published: May 2023

Semantic variant primary progressive aphasia (svPPA), a well-known subtype of the frontotemporal dementia often shows peculiar clinical features and structural neuroimage findings. To strengthen the accuracy of a clinical diagnosis, amyloid positron emission tomography-computed tomography (PET-CT) might be helpful. However, in patients with late-onset svPPA, an admixture of the various neuropathology would interfere with diagnostic approach. Herein, we report a case of late-onset bilateral svPPA showing a regional amyloid deposition on PET-CT scan.
TWNK Gene Associated Perrault Syndrome Patient with Neurological Features
Authors: Kim Hyung Ki , Bae Jae Young , Lim Ji Won , Seok Jin Myoung , Park Jongkyu
Published: May 2023

Perrault syndrome 5 is a rare autosomal recessive disorder that is characterized by the association of sensorineural hearing loss and ovarian dysgenesis in females with diversity of neurologic deficits due to variants of twinkle mtDNA helicase (TWNK) gene. Since neurologic deficits develop gradually, patient is often misdiagnosed with other neurological disease during early age. Herein, we report a case of genetically diagnosed Perrault syndrome 5.
Pazienti eleggibili al trattamento con inibitori dei PCSK9: quali e quando?
Authors: Agosti Sergio , Casalino Laura , Aste Milena , Zito Giovanni Battista
Published: May 2023

Il trattamento delle dislipidemie ha subito un grosso impulso dopo la pubblicazione delle ultime Linee Guida Europee del 2019. In tali LG si conferma come la riduzione assoluta delle LDL sia proporzionale alla riduzione del rischio cardiovascolare, come l’abbassamento delle LDL (con statine, ezetimibe e PCSK9) sia sicuro ed efficace anche per valori inferiori a 55 mg/dl, e come l’intensità del trattamento dovrebbe basarsi sul profilo di rischio del paziente, indipendentemente dalle cause del rischio stesso (prevenzione primaria o secondaria) e dal valore di LDL al baseline. A fronte di tali raccomandazioni ad oggi purtroppo la percentuale di pazienti ad alto e altissimo rischio che raggiungono i target LDL raccomandati è circa il 20%. Tale forte discrepanza tra evidenze scientifiche e pratica clinica dipende da molteplici fattori che abbiamo voluto affrontare nel nostro articolo, con l’obiettivo di aumentare la consapevolezza del lettore dell’importanza del trattamento dell’ipercolesterolemia e di quali strumenti mettere in atto per superare la nostra inerzia terapeutica
Humour in Chetan Bhagat’s The Girl in Room 105 and One Arranged Murder: A Study With Special Reference to His Creation of Dark Humour and Satire
Authors: Ahmed M. Abdul Majid , Karim Mohammad Rezaul , Das Nabamita
Published: May 2023

Humour is the predominant element in all the novels of Chetan Bhagat. His novels contain ‘black humour’ which is a form of humour that presents sorrows and sufferings as very mean or that regards human existence as ironic and pointless but somehow comic. ‘Black humour’ is also called ‘Black Comedy’ or ‘Dark Humour’, and the idea that people are powerless victims of fate and character is frequently used to illustrate farce and low humour. The novelist uses humour to reflect the realistic picture of contemporary society. Humour can be more successful in one’s native language. Though the novelist writes in English, he uses very simple language which seems to be one’s own native tongue. The present paper is an attempt to explore humorous elements in Chetan Bhagat's most recent two novels, ‘The Girl in Room 105’ and ‘One Arranged Murder’, with special reference to black humour and satire.
An Exploration of Student Interpreters’ Attitudes Towards the Undergraduate Interpreting Training Programmes at Yemeni Universities
Authors: Al-Sowaidi Belqes , Mohammed Tawffeek
Published: May 2023

This study investigates the attitudes of trainee interpreters towards their training programmes at Yemeni universities. 61 interpreters in Taiz province participated in the study. A 16-item questionnaire was designed to explore their attitudes towards their programmes. The findings of this study show that the interpreters are not satisfied with the current programmes. The results also show that the programme does not adequately enhance the interpreting competence of would-be interpreters. The programme is mainly concerned with the enhancement of the linguistic and cultural competencies, paying less attention to other components of interpreting competence such as instrumental, psycho-physiological, and strategic. The results also show that respondents are not satisfied with the content of instructional modules, activities used in the training, the time allocated for practicums, and the amount of technology integration. This study has also investigated the interpreting directionality of beginner and advanced student interpreters at Al-Saeed University by quantitatively analysing their final scores in interpreting modules. Beginner and advanced groups in the current study demonstrate different levels of interpreting competence in both directions. The results from various statistical tools show that student interpreters, whether beginners or advanced, are more competent to interpret into their mother tongue, while very few of them show balanced skills in both directions. Additionally, the overall scores of beginner and advanced student interpreters in both directions do not reflect the expected level of proficiency.
The Ambivalent Depictions of Arabs in Naomi Shihab Nye’s Habibi and Diana Abu-Jaber’s Crescent
Authors: AlOmari Ehab Hashem , Awajan Nasaybah Walid
Published: May 2023

The study aims to identify how Arab-American authors Naomi Shihab Nye and Diana Abu-Jaber depict Arabs in their novels, Habibi and Crescent. Additionally, the study attempts to compare and contrast between the two writers’ depictions of Arabs in their novels. To achieve the objectives of the study, the theory of Post-colonialism is used; more specifically, Edward Said’s views from his book Orientalism are applied to both novels. The study concludes by showing how both Nye and Abu-Jaber  depict Arab characters in an ambivalent way within their works, Habibi and Crescent, respectively, in that they sometimes present Arabs in a positive light and other times in a negative light. The study also concludes with a set of concepts that include lack of identity, hybridity, and multiculturalism that have affected Arab-Americans and influenced their cultural values. These representations are also considered ambivalent.
The Validity of Hiring Native and Non-Native English-Speaking Instructors: Professional Observers', Learners', and Programme Administrators' Perceptions
Authors: Murtada Abeer Yahya , Alsuhaibani Yasser Abdulrahman
Published: May 2023

In the recent past, considerable attention has been directed towards the issues relating to non-native English speaker teachers (NNESTs) and native English speaker teachers (NESTs) in English language teaching (ELT), especially their employability as English language teachers. This study aimed to investigate the hiring process for an English as a foreign language (EFL) instructor position. The study has adopted a mixed-design approach using a structured questionnaire on 212 students from the Preparatory Year Program (PYP) at Princess Nora University (PNU) and the Common First Year (CFY) at King Saud University (KSU) and semi-structured interviews on six programme administrators and professional observers from the higher education language institutions in Saudi Arabia to achieve the study’s objectives. Specifically, this study examined three areas: a) the programme administrators’ perception of the hiring criteria of both NESTs and NNESTs; b) the professional observers' perception of the hiring criteria used, linking them to the performance of both NESTs and NNESTs in EFL classes and providing criteria that they deem necessary; and c) the learners' perception of the characteristics of an effective EFL instructor to support the latter's perception. The results revealed that being a native speaker was not important from the perception of programme administrators, professional observers, and learners. However, programme administrators, professional observers, and learners gave more importance to other criteria such as pedagogical skills, personal qualities, and the ability to teach.
Comprehension of Metaphors by Typically Developing Arabic-Speaking Jordanian School Children
Authors: Rumman Ronza N. Abu
Published: May 2023

This paper reports on the findings of a study investigating the comprehension of Arabic metaphors by Jordanian school children. Thirty typically developing school children aged 6, 8 and 10 years old performed a metaphor verbal comprehension task based on 10 lexicalized metaphorical expressions incorporated into 10 short stories. Each short story ends with a target metaphorical expression and is followed by a question about identifying the referent of the metaphorical expression. The results show that old children were better at comprehending metaphors than young children. The study concludes that the comprehension of metaphor develops significantly with chronological age. Furthermore, the degree of the child’s familiarity with given metaphors plays a crucial role in influencing the comprehension of metaphors.
Approaches to Bangla-Arabic Translation: Subtleties and Solutions
Authors: Akan Md. Faruquzzaman , Abdul-Rab Salahud Din , Salafi Aziz Abdulrab Saleh
Published: May 2023

This study addresses some significant issues related to Bangla-Arabic translation and their possible solutions. It describes the types of translation and the role played by the translator in the overall process. As translation is a complex and subtle area of language studies, translators must be conscious of all the probable professional intricacies. They primarily deal with the meanings; however, they also manipulate the transfer of all the corresponding characteristic elements of the source language into the target one. Translation from Bangla to Arabic is more complicated since it manages two languages with entirely different origins. The bulk of the complications in translation arises because of the fundamental differences between the two languages’ grammar, lexicon, usage, stylistics and phonology. This research tries to equip the Bangla-Arabic translators with the necessary knowledge about the related problems and the skills that may help them find smart solutions.  Finally, some practical recommendations are given to the experts as well as student translators and feasible suggestions are also extended to the future researchers.
The Artistic Space of the Topic of Inclusion in the Literature of Ukraine
Authors: Sharova Tetiana , Pavlenko Anatolii , Nisanoglu Natalia , Gladkykh Hanna , Bodyk Ostap
Published: May 2023

The research provides a quantitative and content analysis of literary works on the topic of inclusion, which were written by Ukrainian writers in the period of 2013-2019. The advantages of reading literary works on the topic of inclusion were revealed. The authors analyzed the factors of effective inclusive education, including those with the use of literature, where characters with disabilities are displayed. A total of 15 literary works were analyzed. The largest number of books on the topic of inclusion were published by the Ukrainian “Stary Lev Publishing House”. Most of the works on the topic of inclusion were written in 2015. It has turned out that not all the books are available for reading in full. It was found that Ukrainian literature on the topic of inclusion describes the life situations of the main characters who have congenital defects (blindness, a hump on the back, Down’s syndrome, Asperger’s syndrome, autism), who have some defects developed in car accidents (deafness) or illness. In addition, the age of readers, which should be focused on when reading books, turned out to be diverse: 3-8 years old (7%), 6-9 years old (33%), 9-12 years old (47%), over 13 years old (13%). In the analyzed literary works, 53% of the main characters are female, and 47% of the characters are male. In further research, it is planned to analyze the quantity and quality of illustrations that accompany and supplement the content of works on the topic of inclusion which were written by Ukrainian writers.
Depiction of Polygamous Character Traits in Che Husna Azhari’s Mariah
Authors: Azmi Mohd Nazri Latiff , Nathan Devia d/o Kamala , Abdullah Ahmad Taufik Hidayah , Hassan Isyaku
Published: May 2023

In Malaysia, literary texts produced in English remain a challenging terrain, especially among Malay writers who must cautiously negotiate between their Malay identity, religion, and cultural globalization. For instance, Che Husna Azhari’s literary works, especially her notable short story Mariah, have received tremendous scholarly attention recently. Mariah has been criticized from several viewpoints, such as the playwright’s conscious self that forms identity and gender. Thus, using a context-oriented approach, this analysis aims to explore how the Malaysian author, Che Husna Azhari, depicts polygamous character traits in Mariah from a feminist perspective. The feminist rendering employed in this analysis could interestingly reveal how a female writer portrays the issue of polygamy. The analysis revealed that through major characters, Azhari boldly depicts Muslim masculinity, polygamous tendencies, and lust toward women, particularly in the Imam’s character. Yet, the narrative tends to mirror patriarchy in Malay society for crediting the use of religion to suppress women. This analysis could advance our understanding of how female characters are represented by a female writer within the socio-cultural and religious contexts of typical Malay society. There is a need, therefore, for modern writers to reassess the narratives of women and polygamy in literary works. This step can guide the reader’s understanding of polygamy as a hotly-debated topic as well as enlighten the public about the widespread misconceptions about women's issues in society.
Figurative Language Used by Australian Facebookers During COVID-19 Pandemic
Authors: Amer Mamoun I Bani , Rababah Luqman M
Published: May 2023

This study investigated the metaphorical speech acts used by Australian commentators on Facebook during COVID-19. The sample contained 50 Facebook comments that were analyzed qualitatively. The study adopted Searle taxonomy of speech acts, namely, directive, assertive, expressive, commissive, and declarative. This helped in identifying the different functions of the metaphorical speech acts. Moreover, Austin taxonomy of speech act forms, namely, locutionary, illocutionary, and perlocutionary, was adopted. The findings revealed that the most common types of metaphors that were used by the Australian commentators were war and conflict metaphors, followed by psychological status metaphors and irony metaphors. The study found that war and conflict metaphors were the most commonly used forms of speech by the commentators. This is in alignment with the literature that also highlights how the advent of a crisis, such as COVID-19, results in excessive use of war and militarized metaphors. The study found that the most common speech act was directive, while expressive was the least common form used by Australian commentators during the COVID-19 pandemic.
Conventional Implicatures in Ukrainian Discourse
Authors: Bezugla Liliia , Govorukha Nataliia , Kryvoruchko Sergiy , Malaya Olesya
Published: May 2023

The present study aims at the analysis of conventional implicatures (Grice, 1991) actualized in Ukrainian dialogical discourse. The distinction between conventional and conversational implicatures is described. We argue that what is commonly considered conventional implicature is in fact implicature only in discourse. Implicatures are inherently conversational because they are intended by the speaker and derived by the addressee in discourse. Therefore, it makes sense to regard conventional implicatures as such that are actualized not only in discursive context (such being the case with conversational implicatures), but by certain language means in virtue of their semantics. They serve as triggers allowing the addressee to derive implicature through its conventional meaning. Implicature triggers are culture-specific, since their semantics is determined by conventions of a particular natural language. Depending on language status of the trigger, conventional implicatures are divided into lexical, paroemiac and syntactic.
Arabization or Domestication? Case Study of Information Structure Shift in Aphorisms
Authors: Anis Muhammad Yunus
Published: May 2023

Al-Hikam aphorism is a descriptive factual genre in which the patterns of the text structure are distinctive and aesthetic. The structure of the information facilitates the linear pattern to be arranged in any micro manner. The structured information may have various themes (topical, textual, and interpersonal). The aphorisms, which are originally Arabic, have been translated into English. This study investigates the techniques, methods, and ideology of al-Hikam English translation and the impact of the shift in thematic structure on the quality of translation. Using a qualitative design by utilizing Spradley model data analysis modified by Santosa (2021), this study suggests that al-Hikam aphorism translation has the tendency towards the target language with the ideology of domestication as seen from the translation techniques being used. The application of translation techniques also causes the phenomenon of thematic structures shift that affects the quality of translation. Therefore, textual competence must be understood by a translator.
Feminist Reading of Leila Aboulela’s “The Ostrich”
Authors: Alkhatib Wafa Yousef
Published: May 2023

The marginalized and oppressed women in Sudan, alongside the subaltern women living on the margin, are depicted in the current work. “The Ostrich” by Laila Aboulela shows the protagonist’s life of Sumra both in Khartoum, Sudan, and London in the UK. Sumra represents Sudanese women struggling hard to find their place in a patriarchal society. The structure of this article can be articulated in two arguments; the empowerment of patriarchal supremacy and the power of tradition implanted in Sudan and most third-world countries to marginalize and silence the role of women so that they can never be heard. Although women have got their studies at universities, they are still marginalized and have no full right to decide for themselves. Appropriating the analytical descriptive approach, the current study aims to demonstrate the marginalization and oppression of women in Sudan.
Управление трудовым потенциалом будущего в условиях международной проектной деятельности
Authors: Гагаринская Г.П. , Кузнецова И.Г. , Мюллер Е.В. , Чернышенко В.С.
Published: May 2023

Рассматриваются вопросы реализации Болонского процесса и интеграции системы высшего профессионального образования России в мировую систему высшего образования. Представлены теоретическое обоснование и разработка методических и практических рекомендаций по управлению трудовым потенциалом вуза в условиях реализации международной проектной деятельности. Издание может быть использовано в научно-исследовательской деятельности, при изучении курсов «Управление персоналом», «Управление проектами» аспирантами, магистрантами и студентами старших курсов.
Monetary Reaction Function in Indonesia During Inflation Targeting Period
Authors: Hervino Aloysius Deno , Insukindro Insukindro , Hardi Amirullah Setya , Setiastuti Sekar Utami
Published: May 2023

This study analyzes the monetary reaction function with shocks and the fear of floating phenomenon in the inflation targeting period in Indonesia. This study uses a new neoclassical synthesis approach. The unit root test result explains that all variables are stationary or I(0), and the long-run regression model is estimated. The results show that interest rates respond positively to future inflationary (counter-cyclical) in the log-run. The effect of triple shocks on interest rates in Indonesia is estimated using the Forward-Looking Model (FLM) and Error Correction Model (ECM). Using a predictive model performance (informal test), the best model in this study is FLM. In the short-run, only fluctuations in world oil prices significantly affect interest rates (counter-cyclical policy). Furthermore, BI's response to future inflation cannot be compared with BI's response to economic fluctuations, so this study has not been able to explain the significant effect of economic fluctuations on deposit interest rates. It means that the fear of the floating phenomenon cannot be explained in this study.
The Risk-Taking Channel and Monetary Transmission Mechanisms in Indonesia
Authors: Silalahi Pristanto , Falianty Telisa Aulia
Published: May 2023

This study aims to analyze monetary and macroprudential policies through risk taking banks in Indonesia. The importance of risk-taking channel analysis in the transmission mechanism of monetary policy is that it is a newer route and is different from the bank lending channel that has been previously proposed in monetary policy theory. This risk-taking channel affects the supply of credit by banks through the bank's decision to channel credit based on changes in bank behavior in dealing with bank risk. The study also recognizes the impact of monetary and macroprudential policies and the role of the characteristics of banks, as well as macroeconomic conditions such as economic growth and inflation rates. The analytical method used is fixed effects through panel data in the period 2012-2019. This study uses 3 types of proxies to measure risk, first with the Z-score measurement method, second with the ratio of the number of risky assets to total assets and third, the ratio of the number of bad loans to total assets. The results of this study found that the impact of monetary policy and macroprudential policy significantly affects bank risk. In addition to the main variables, this study also uses GDP growth and inflation variables as control variables for macroeconomic conditions that significantly effect on bank risk, liquidity, and bank size variables as control of bank characteristics which also significantly affect bank risk. So, it can be concluded that the risk-taking channel exists in Indonesia’s banking.
INTERNALISASI URGENSI PENCEGAHAN PELECEHAN DAN KEKERASAN SEKSUAL BAGI SISWA
Authors: Dini Alya Muflihatud , Qomariyah Aanisah Nurul , Ardiansyah Adistya Eka Sis , Harahap Adinda Putri , Huda Ahmad Tirtho Faidl , Ramadhan Angga Gilang
Published: May 2023

The purpose of this activity is to provide an understanding and also to increase the knowledge of students, especially in MAN 2 Malang City about education regarding the prevention of sexual harassment and violence as a self-help before entering the campus world. The method used is in the form of socialization. While this socialization activity is carried out in two ways, the first is the presentation of the socialization material by the resource person using the talk show method, then the second is continued with group discussions. Don't forget that at the end of the activity there is an evaluation in the form of a post-test to find out how far the students' understanding is after getting this socialization briefing. The data that the author collects are reports of activities in the field which are supported by documentation in the form of photos and videos of activities, which are then analyzed and processed to be presented descriptively in this article. The subjects of this activity were fifty students at MAN 2 Malang City consisting of twenty student council students and 30 students for each class 11 head and administrator. The implementation of this socialization activity went smoothly as planned, the students were very enthusiastic and also eager to ask various questions. By carrying out this activity, students get an idea of how to act if there are acts of harassment and sexual violence that occur around them.Tujuan dari adanya kegiatan ini yaitu untuk memberikan suatu pemahaman dan juga untuk meningkatkan pengetahuan siswa, khususnya di MAN 2 Kota Malang mengenai edukasi seputar pencegahan pelecehan dan kekerasan seksual sebagai pembekalan diri sebelum memasuki dunia kampus. Metode yang digunakan yaitu berupa sosialisasi. Adapun kegiatan sosialisasi ini dilakukan dengan dua cara, yang pertama yaitu pemaparan materi sosialisasi oleh narasumber dengan metode talk show kemudian yang kedua dilanjut dengan diskusi secara berkelompok. Tidak lupa di akhir kegiatan terdapat evaluasi berupa post-test untuk mengetahui seberapa jauh pemahaman siswa setelah mendapatkan pembekalan sosialisasi ini. Data yang penulis kumpulkan yakni laporan kegiatan di lapangan yang didukung dengan dokumentasi baik berupa foto maupun video kegiatan, yang kemudian dianalisis serta diolah untuk disajikan secara deskriptif di artikel ini. Subyek kegiatan ini yaitu 50 siswa di MAN 2 Kota Malang yang terdiri dari 20 siswa OSIS dan 30 siswa tiap ketua dan pengurus kelas 11. Pelaksanaan kegiatan sosialisasi ini berjalan dengan lancar sesuai rencana, terlihat para siswa sangat antusias dan juga bersemangat mengajukan berbagai pertanyaan. Dengan dilaksanakannya kegiatan ini, para siswa memperoleh gambaran bagaimana cara bertindak apabila terdapat tindak pelecehan serta kekerasan seksual yang terjadi di sekitar mereka.
PELATIHAN PENGOPERASIAN PLATFORM PEMBELAJARAN ONLINE DALAM MASA PANDEMI COVID-19 BAGI ANAK-ANAK DESA BATUAJI KECAMATAN RINGINREJO KABUPATEN KEDIRI
Authors: Aprilia Riska , Intan Tri Damayanti , Sari Ninik Yustina , Putri Lifa Rosiana
Published: May 2023

TRAINING OF ONLINE LEARNING PLATFORM OPERATIONAL PROCEDURE FOR CHILDREN IN BATUAJI, KEDIRI, DURING THE COVID-19 PANDEMICOnline learning is commonly carried out. Especially during the COVID-19 pandemic, online learning is implemented to prevent the extensive spread of COVID-19. However, during its implementation, online learning faces a number of hindrances, such as the student’s inability to operate the online learning platform, which reflects the unpreparedness for online learning. Therefore, we conducted training on online learning platform operations for children from Batuaji, Kediri, Indonesia. This training aimed to help students operate a number of online learning platforms, such as  google classroom, zoom, google meet, edmodo, quizizzz, and whatsapp. The elementary school and junior high school-age children participated in this training. The training process was initiated by introduction, short material delivery related to the online learning platforms, quizzes, and evaluation. This training is helpful for the participants, as reflected by their great enthusiasm during the training activities and great understanding of online learning platforms’ operation procedures after attending the training.Pembelajaran online merupakan kegiatan yang sedang dilaksanakan selama pandemi COVID-19. Hal ini dilakukan guna menghindari penyebaran COVID-19 yang semakin meluas. Sesuai dengan praktiknya kegiatan pembelajaran online menemui beberapa hambatan, salah satunya yakni banyaknya anak-anak yang belum menguasai penggunaan platform pembelajaran online sehingga menimbulkan ketidaksiapan dalam pembelajaran online. Oleh karena itu, kegiatan ini bertujuan untuk memberikan solusi dengan mengadakan pelatihan pengoperasian platform pembelajaran online dalam masa pandemi COVID-19 bagi anak-anak di Desa Batuaji Kecamatan Ringinrejo Kabupaten Kediri guna membantu agar mereka memahami cara mengoperasikan beberapa platform pembelajaran online seperti google classroom, zoom, google meet, edmodo, quizizz dan whatsapp. Pelatihan ini dilakukan bagi anak-anak SD dan SMP dengan rangkaian kegiatannya diawali perkenalan, pemaparan materi tentang platform pembelajaran online secara singkat, praktik kuis, dan evaluasi pelatihan. Hasil pelatihan ini sangat bermanfaat, bahkan semua peserta pelatihan sangat antusias selama kegiatan berlangsung serta mereka juga memahami beberapa aplikasi yang baru mereka kenal selama pelatihan.
MENINGKATKAN PEMBELAJARAN MEMBACA KRITIS MAHASISWA TERHADAP PENGEMBANGAN KETERAMPILAN INDIVIDU MELALUI SQ3R
Authors: Ilmah Fadhilatul , Putri Aguwin Tarissa , Mahesta Arindra Dwi , Amalia Lutfi Ana
Published: May 2023

IMPROVING STUDENT CRITICAL READING LEARNING TOWARDS INDIVIDUAL SKILL DEVELOPMENT THROUGH SQ3RScience and technology are developing rapidly so that they affect college graduates. Mastery of science and technology is needed so that graduates are able to compete in the world of work. Education plays an important role in forming quality human beings with the aim of being able to follow the development of science and technology. Education emphasizes both cognitive and non-cognitive aspects as critical thinking skills. By thinking critically, individuals will be able to make decisions to be taken, be open to differences of opinion, and be able to know and differentiate the reasons why other people have different decisions and opinions. For this reason, researchers have efforts to improve students' critical reading learning, towards the development of individual skills through SQ3R (survey, question, read, recite, review). The purpose of this research is to find out about SQ3R, develop critical reading skills, and the relationship between SQ3R and critical reading for individual skills. In this study using the literature review method, the source used is Google Scholar in the form of journals and articles. The results of the research are shown from the student learning outcomes that have been achieved through SQ3R, so that they are able to read critically.Ilmu pengetahuan serta teknologi berkembang cepat sehingga berpengaruh pada lulusan perguruan tinggi. Penguasaan ilmu pengetahuan dan teknologi sangat diperlukan agar lulusan mampu bersaing di dunia kerja. Pendidikan berperan penting dalam membentuk manusia yang berkualitas dengan tujuan mampu mengikuti perkembangan IPTEK. Pendidikan menekankan baik pada aspek kognitif maupun non kognitif sebagai kemampuan berpikir kritis. Dengan berpikir kritis individu akan mampu membuat keputusan yang akan diambil, terbuka dengan adanya perbedaan pendapat, serta bisa mengetahui serta membedakan alasan mengapa orang lain mempunyai keputusan dan pendapat yang berbeda. Untuk itu peneliti memiliki upaya meningkatkan pembelajaran membaca kritis pada mahasiswa, terhadap pengembangan keterampilan individu melalui SQ3R (survey, question, read, recite, review). Adanya penelitian ini memiliki tujuan untuk mengetahui tentang SQ3R, mengembangkan kemampuan membaca kritis, dan hubungan SQ3R dengan membaca kritis untuk keterampilan individu. Dalam penelitian ini menggunakan metode literatur review, sumber yang digunakan yakni pada google scholar berupa jurnal dan artikel. Hasil penelitian ditunjukkan dari hasil belajar mahasiswa yang telah tercapai melalui SQ3R, sehingga mampu membaca kritis.
IMPLEMENTASI MODEL PROJECT BASED LEARNING BERBASIS FLIPPED CLASSROOM TERHADAP PROBLEM SOLVING SKILLS SISWA
Authors: Siburian Jodion , Tohiri Dhiya Millatika , Mataniari Raissa
Published: May 2023

Abstrak. Pemecahan masalah Keterampilan merupakan salah satu keterampilan siswa yang perlu digunakan. Salah satu upayanya yaitu pembelajaran berbasis Flipped Classroom dengan menggunakan model pembelajaran Project Based Learning. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh implementasi model Project Based Learning berbasis Filpped Classroom terhadap Problem Solving Skills siswa kelas X IPA SMAN 11 Muaro Jambi. yang digunakan adalah Quasi Eksperimental Designs dengan subjek penelitian yang dibuka 53 siswa yang terbagi dalam Rancangan dalam dua kelas eksperimen dan sebagai kelas kontrol. Hasil penelitian berupa kemampuan Problem Solving siswa yang dilihat dari nilai pretest dan posttest.Kelas ekperimen diperoleh nilai rata-rata 83,33 sedangkan kelas kontrol diperoleh nilai rata-rata 73,70. Hasil uji hipotesis dalam penelitian ini didapat thitung = 3,19 dan ttabel = -1,67, dapat diketahui nilai thitung lebih dari ttabel. Merujuk pada hasil analisis data maka dapat dikatakan bahwa model Pembelajaran Berbasis Proyek Kelas Berbasis Flipped berpengaruh terhadap Keterampilan Pemecahan Masalah siswa.Abstract. Problem solving skills are one of the student skills that need to be trained. One of the efforts is Flipped Classroom-based learning by using Project Based Learning model. This study aims to find out how the effect of the implementation of the Filpped Classroom-based Project Based Learning model on the Problem Solving Skills of class X science students at SMAN 11 Muaro Jambi. The design used was Quasi Experimental Designs with 53 students as research subjects divided into two classes, the experimental class and the control class. The results of the study are described as follows, the problem solving ability of students is seen from the pretest and posttest scores. For the experimental class, average value was 83.33 and control class obtained an average value of 73.70. The results of hypothesis testing in this study obtained tcount = 3.19 and ttable = -1.67, so it can be seen that the value of tcount lebih ttable. Referring to the results of data analysis, it can be concluded that the Project Based Learning model based on Flipped Classroom has an effect on students' Problem Solving Skills.
PENGEMBANGAN CELL THRU AUGMENTED REALITY PADA MATAKULIAH BIOLOGI SEL
Authors: Setiawan Deny , Fitriyati Umi , Fachrunnisa Rifka , Sunarmi Sunarmi , Izza Jasmine Nurul , Firdaus Zahra
Published: May 2023

Abstrak. Penelitian dan Pengembangan dilakukan untuk menghasilkan produk berupa Media Cell Thru Augmented Reality yang multirepresentatif pada matakuliah Biologi Sel yang valid dan praktis. Model ADDIE digunakan dalam pengembangan produk yang disusun. Tahap Analisis, Desain, Pengembangan dan Evaluasi dilakukan dengan lengkap, namun tahap Penerapan belum dilaksanakan. Data kuantitatif yaitu data hasil uji validitas dan kepraktisan dianalisis secara deskriptif. Data kualitatif yaitu data saran dari validator, praktikan, dan responden dianalisis secara kualitatif, dan dievaluasi sebagai dasar revisi produk. Hasil penelitian menunjukkan bahwa produk telah valid, dengan rata-rata dari validator ahli materi, ahli perangkat dan ahli media berturut-turut adalah 100%, 96.75%, 97.33%, serta produk telah diperbaiki sesuai saran. Produk juga dinyatakan telah praktis dengan rata-rata 96.82%. Hasil produk yang dikembangkan dapat dilanjutkan pada tahap berikutnya.Abstract. Research and Development was carried out to produce a product in the form of Cell Thru Augmented Reality Media which is multi-representative in Cell Biology courses that are valid and practical. The ADDIE model was used in the development of the products that were prepared. Analysis, Design, Development and Evaluation stages are carried out completely, but the Implementation stage has not been carried out. Quantitative data, that is, data from validity and practicality tests, were analyzed descriptively. The suggestions from validators, practitioners, and respondents, was analyzed qualitatively, and evaluated as a basis for product revision based on qualitative data. The results showed that the product was valid, with an average of 100%, 96.75%, 97.33% from material expert validators, device experts and media experts respectively, and the product had been improved according to suggestions. The product was also declared practical with an average of 96.82%. The results of the developed product can be continued at the next stage.
Knowledge levels of fetal rights in Turkish pediatric nurses
Authors: OZAKAR AKCA Selen , TURAN Ahu Pınar , KALKAN YALCIN Dilek
Published: May 2023

BACKGROUNDFetal rights are violated due to acts such as negligence, ignorance, false beliefs and substance addiction. Pediatric nurses, as defenders of the fetus, should inform pregnant women and the family about the rights of the fetus and assist the family in the decision-making process. This study aims to determine the knowledge levels of pediatric nurses on fetal rights.
METHODSThis cross-sectional study involved 121 nurses working in the pediatric clinic of a training and research hospital. Data about characteristics of pediatric nurses and knowledge levels about fetal rights were collected. Statistical analyses were made with SPSS package program. Mann Whitney U test and Kruskal Wallis test was used to analyse the data.
RESULTSIn this study, it was found that 76.9% of the pediatric nurses participating in the study did not have prior knowledge about fetal rights. There was a statistically significant difference between the participants’ mean scores of knowledge levels about fetal rights and their age, educational status, status of prior knowledge about fetal rights and where this knowledge was gained (p<0.05).
CONCLUSIONAs a result, it was found that most of the pediatric nurses did not have prior knowledge about fetal rights, and that their knowledge about fetal rights was lacking. Considering that pediatric nurses, as the defenders of the fetus, have a duty to inform the family about fetal rights, it is recommended to plan trainings on fetal rights for pediatric nurses.
Anal human papillomavirus genotype distribution and its associations with abnormal anal cytology among men who have sex with men
Authors: Somia I Ketut Agus , Merati Tuti Parwati , Sukmawati Dewi Dian , Winarti Ni Wayan , Indira IGAA Elis , Putra Ida Bagus Dwija , Prasetia Made Yogi Oktavian
Published: May 2023

BACKGROUND Anal human papillomavirus (HPV) is associated with the severity of anal cytologic abnormalities that are precancerous lesions. Knowledge of HPV type distribution in populations at risk for anal cancer is needed. This study investigated anal HPV infections and cytological abnormalities among men who have sex with men (MSM).
METHODS A cross-sectional study was conducted involving 90 men aged >30 years with a history of anal sexual intercourse with men. Demographic characteristics and sexual behaviors were collected by using a self-completed questionnaire. Anal cytological results were examined, and HPV genotyping was performed by the Linear Array HPV genotyping test. Descriptive analyses of subject characteristics, prevalence, and 95% confidence intervals (CI) were performed. A chi-square test was used to determine their associations with high-risk HPV infection and cytological abnormalities.
RESULTS The overall prevalence of abnormal cytology was 32% (24/75), atypical squamous cells of undetermined significance (ASCUS) 17.33 % (13/75), 14.66% (11/75) were classified as low-grade SIL (LSIL) and no participant had high-grade SIL (HSIL). Prevalence of HPV infection with normal cytology was 86.27% (44/51), ASCUS 92.30% (12/13), and LSIL 100% (11/11). The most common types of anal HPV in participants with cytological abnormalities are HPV 16, HPV 18 for high-risk HPV, and HPV 11, HPV 6 for low-risk HPV. There were no associations between the predictor variables and the abnormal cytology (p>0.05).
CONCLUSION There was a high prevalence of HPV infection in MSM with abnormal anal cytology. A routine anal Pap smear program and vaccination are needed to prevent HPV infection and anal dysplasia in MSM.
Breast cancer survivors and behavior: cancer care in the time of COVID-19 in Indonesia
Authors: Soewoto Widyanti
Published: May 2023

The COVID-19 pandemic caused significant disruptions in cancer care, and preliminary research suggests that these disruptions are associated with increased levels of psychosocial distress among cancer survivors. Indonesia initially reported positive cases in early March 2020, followed by regular extensive occurrences across 34 provinces. The disease causes acute respiratory failure among people with specific comorbidities, including geriatric disorders, diabetes, cardiovascular and respiratory diseases, and cancer. Consequently, the patients’ conditions become more severe, possibly leading to a higher mortality rate. Individuals with cancer are at particularly elevated risk of a severe course of COVID-19 because they tend to be of older age and are at a greater risk for needing intensive care and for mortality. A reasonably good comprehension of the current COVID-19 outbreak, poor awareness of the primary disease and subsequent therapy program, and minimal understanding of the importance of continuing treatment during the pandemic are the probable factors causing the fear of contracting the COVID-19 virus that poses a significant threat of aggravating the existing breast cancer conditions in most patients. This anxiety shows a drastic impact in altering the behavioral patterns of survivors undergoing therapy. There is a very good understanding of how it is caused by the SARS-COV2 virus. Meanwhile, there is a severe lack of understanding of cancer and the therapeutic program. The patients are more afraid of contracting this virus than they are of their cancer. Patients prefer development of their cancer to contracting the SARS-COV2 virus. Therefore, massive education and supervision are needed for cancer patients to understand the COVID-19 pandemic and ensure that routine checks are appropriately managed.
Significance of salivary poly (ADP-ribose)-polymerase in the assessment of age-dependent pathological processes in the oral cavity
Authors: Bazarnyi V.V. , Kopenkin M.A. , Polushina L.G. , Maximova A.Yu. , Sementsova E.A. , Mandra Yu.V.
Published: May 2023

Age-related changes in the oral cavity are accompanied by the development of age-related pathology, such as chronic periodontitis (CP). Although apoptosis plays a certain role in its pathogenesis, this fact, however, has not been evaluated clinically, and the diagnostic information content of biomarkers of apoptosis and aging has not been determined. The aim of the study was to evaluate the content of cleaved poly-(ADP-ribose)-polymerase (cPARP) and caspase-3 (Casp3) in mixed saliva of elderly patients with age-related dental diseases and in mature patients with mild to moderate CP. The study included 69 people. The control group included 22 healthy young volunteers aged 18 to 44 years. The main group included 22 elderly patients aged 60 to 74 years. They were divided into subgroups according to clinical manifestations: occlusion (comparison group), periodontal, and dystrophic syndromes. Additionally, a group of 25 patients of mature age from 45 to 59 years old with mild to moderate CP was analyzed. The content of salivary Casp3 in patients with occlusion syndrome was lower than in healthy young people (p=0.014). In patients with the periodontal syndrome, the content of cPARP was higher than in the comparison group (p=0.031). The group with dystrophic syndrome had the highest level of Casp3 in comparison with the control group and the comparison group (p=0.012, p=0.004, respectively). There were no statistically significant differences between patients of different age groups with mild to moderate CP. Evaluation of the correlation between cPARP and Casp3 levels revealed a direct relationship in the group of elderly patients and in patients with mild CP (r=0.69, r=0.81, respectively). We assessed the effect of Casp3 levels on changes in the cPARP levels by means of a simple linear regression analysis. The cPARP level correlated with the content of Casp3 (r2=0.555). According to the results of the ROC analysis, it was found that using the cPARP indicator it would be possible to distinguish between groups of elderly patients with periodontal and occlusion syndromes (AUC=0.71), while using Casp3 it would be possible to distinguish patients with the occlusion syndrome and the control group (AUC=0.78). Since the level of Casp3 in young people is significantly higher than in the elderly patients, its decrease can be considered as a potential salivary biomarker of aging. The level of studied cPARP in the elderly has clinical value in periodontal syndrome and low age dependence.
The Effects of Cigarette Smoking on Venous Flow Volume of Lower Extremity
Authors: Kalayci Tugce , Sonmezgoz Fitnet , Kestelli Mert
Published: May 2023

Aims: The purpose of this study was comparing flow volume rates, velocities and diameters of lower extremity arteries and veins of smokers and non-smokers with peripheral arterial disease. Patients and methods: The study consisted of 58 patients, 26 smokers and 32 non-smokers, who had no smoked for at least 5 years prior to the investigation. Colour Duplex Ultrasonography measurements of the common femoral artery, common femoral vein, popliteal artery, popliteal vein, anterior tibial artery, anterior tibial vein, posterior tibial artery and posterior tibial vein were obtained in the supine position. Differences in the diameters, blood flow velocities, and flow volume rates of the vessels were compared according to the sex, age and Colour Duplex Ultrasonography measurements of the patients. Results: The diameters of the common femoral artery, popliteal vein and posterior tibial artery were statistically significantly reduced in smokers. The flow volume rate of the popliteal artery showed a significant correlation with that of crural vessels in non-smokers but not in smokers. Conclusions: The absence of a statistically significant correlation between the measurements of the popliteal artery and crural vessels in smokers shows that cigarette smoking reduces the diameters and flow volumes of crural vessels, potentially giving rise to impaired tissue perfusion.