bluuebunny/crossref_metadata_2025 huggingface dataset:
Representation of Marxism in Historical Film
Authors: Kusumo W R.A Retno Sawitri , Rizka Fathul , Nugroho Abdillah
Published: August 2024

Penelitian ini bertujuan untuk mengidentifikasi bagaimana kostum dan aspek dialog dalam film Merah Putih berkontribusi pada penggambaran ideologi Marxisme, khususnya yang berkaitan dengan konflik kelas sosial. Penelitian ini menggunakan desain penelitian deskriptif kualitatif. Teknik kualitatif berusaha untuk memahami fenomena yang dihadapi peserta studi. Berdasarkan temuan analisis yang dilakukan peneliti terhadap film Merah Putih, Marxisme digambarkan sebagai ideologi yang mendominasi film tersebut.
 
Kata Kunci: Film; Marxisme; Perwakilan; Semiotika
Omentin-1 and Coronary Heart Disease
Authors:   I.P. Pavlov First St. Petersburg State Medical University, Kolodina D.A. ,   St. Petersburg, Russian Federation, Draganova A.S. ,   V.A. Almazov National Medical Research Center; St. Petersburg, Russian Federation, Belyaeva O.D. ,   I.P. Pavlov First St. Petersburg State Medical University; St. Petersburg, Russian Federation, Berkovich O.A. ,   I.P. Pavlov First St. Petersburg State Medical University; St. Petersburg, Russian Federation
Published: August 2024

Aim. The purpose of the review is to summarize the results of studies on the relationship between the level of omentin-1 and coronary artery disease (CAD). Key points. Adipose tissue is currently considered as an endocrine organ synthesizing biologically active factors known as adipocytokines, which may be involved in the pathogenesis of obesity-related metabolic and cardiovascular diseases, in particular, CAD. Omentin-1 is an adipocytokine that is predominantly secreted by visceral adipose tissue and plays an important role in the development of chronic inflammatory diseases, including CAD. Two isoforms of omentin are known: omentin-1 and omentin-2. Omentin-1 is the main circulating form of omentin. Its blood level in healthy people, according to different authors, varies from 1.61 to 815.3 ng/ml. A number of studies have found that the concentration of omentin-1 in the blood of women is higher than that of men, which may be due to sexual dimorphism of adipose tissue. The results of the studies indicate that the levels of omentin-1 circulating in the blood are associated with various metabolic risk factors. The review describes the main molecular mechanisms that determine these effects of omentin-1. A decrease in serum omentin-1 levels can be considered as an independent predictor of CAD and correlates with the severity and prognosis of this disease. A number of studies have established an association between the carriage of various variants of the omentin-1 (ITLN1) gene, CAD and obesity. The article analyzes the available data on the role of the level of omentin-1 in CAD, determined not only in the blood, but also in subcutaneous and visceral adipose tissue. The possible prospects for the use of various molecules capable of increasing the level of omentin-1 in the blood are analyzed. Conclusion. A decrease in the level of omentin-1 may be an independent predictor of CAD and is associated with the severity and progression of the disease. It is likely that omentin-1 can act as an alternative diagnostic tool to ensure optimal management of patients with CAD. Studies of the effect of omentin-1 on the prognosis in patients with various forms of CAD are largely ambiguous and therefore further, more comprehensive studies are needed. Keywords: coronary artery disease, acute coronary syndrome, omentin-1, adipokines, subcutaneous and visceral adipose tissue, omentin-1 gene (ITLN1).
The New Shifting of Community of Practices in Learning Speaking
Authors: Azkia Resyadilla , Nasrullah Nasrullah , Febriyanti Emma Rosana
Published: August 2024

Speaking is a productive skill that cannot be learned quickly but through a process requiring time, energy, and effort. To accelerate the development of speaking skills, English learners, such as those in senior high school, frequently participate in learning communities, such as Community of Practice. Several studies related to community of practices have been conducted, which reported teacher learning community and learning with peers. However, there is a scarce discussion on the concept of a Community of Practice for learning English-speaking skills. Therefore, this research investigated whether the English Club supports students’ speaking skills. The research methodology used in this study is Narrative Inquiry. The subjects of the research were the students and the coach. The research was conducted at SMA Negeri 6 Banjarmasin. The Researcher employed instruments such as observation checklists and interview guidelines. The findings of the study showed that the English Club at SMA Negeri 6 Banjarmasin supports students in developing their speaking skills. The English Club is a community of students who actively practice using English for communication. The club supports informal learning, focusing on developing public speaking skills through storytelling, speech, and debate. The club's activities are designed to enhance students' fluency and pronunciation.
Recent progress in research and development of rare-earth free iron nitride permanent magnet
Authors: An Jihyeon , Kim Seunghan , Park Seungil , Kim Tae-Hoon
Published: August 2024

The high cost of rare earth materials, unstable supply and high demand remain big problems to solve for permanent magnet industries. Thus α″-Fe16N2 has been picked up as one of the most promising rare earth-free magnet candidates because of its use of environmental-friendly raw materials, confirmed giant saturation magnetic flux density (2.9 T), and reasonably high magnetic anisotropy constant (1.8 MJ/m3). Also, α”-Fe16N2 metastable with film form exhibits high tetragonality (c/a=1.1) by interstitial introduction of N atoms, leading to a high magnetocrystalline anisotropy constant (Ku = 1.0 MJ/m3). but synthesis of bulk form has lower properties than thin film (<230 nm) because of magnetic interaction, experimentally low anisotropy, and low density. In this paper, we review the synthetic methods of metastable α”-Fe16N2 with powder and bulk form and discuss the approaches to enhance magnetocrystalline anisotropy of α”-Fe16N2.
Anomaly Detection in Brushless Fan Systems using integration of wavelet approach and convolutional neural network
Authors: Hayder A. Abdulrahem
Published: August 2024

In this research, trustworthiness is improved, and the probability of malfunctioning in DC fan systems is decreased was addressed. This research suggests a new method that employs artificial intelligence to detect faults by combining Convolutional Neural Networks (CNN) with wavelet analysis for better anomaly detection. Ten fans were initially used in the experiment; three were faulty, and seven operated correctly. Data for all fans was collected using an Arduino. Wavelet features were employed to identify faults, followed by a CNN classifier (. Specifically, a binary CNN classifier) to determine the presence or absence of faults. The results were very promising, demonstrating significant potential for improving the reliability of DC fan systems.
The evolution and future directions of bypass surgery
Authors: Enriquez-Marulanda Alejandro , Ramirez-Velandia Felipe , Young Michael , Stout Jeffrey N. , See Alfred P. , Ogilvy Christopher S. , Taussky Philipp
Published: August 2024

Cerebral bypass surgery is one of the most complex and elegant procedures in neurosurgery. It involves several meticulous steps that test the skills of even the most prepared neurosurgeons. This surgery has transcended its traditional role in arterial stenosis and atherosclerosis, expanding its applications to include flow preservation techniques for complex conditions such as aneurysms, tumors, and vascular malformations. The decreased number of procedures performed across many hospitals reflects the development of newer endovascular therapies but is also due to the results of the extracranial-intracranial bypass study, the Carotid Occlusion Surgery Study, and the Carotid and Middle Cerebral Artery Occlusion Surgery Study, which have raised questions about the efficacy of cerebral bypass surgery for individuals with carotid artery occlusion who are prone to ischemic stroke.

Despite this, there is still a potential benefit of bypass surgery for patients with hemodynamic impairment refractory to medical management. Also, revascularization in moyamoya vasculopathy is an effective strategy for preventing ischemic and hemorrhagic events in both children and adults. Additionally, innovations in the technique, such as the flow-regulated bypass and intraoperative flow assessment, aim to minimize perioperative morbidity. Despite bypass surgery being less performed in this current era, the teaching and development of these skills are still encouraged for future neurosurgeons, as a role for bypass will exist for the foreseeable future.
Comparing surgical clipping with endovascular treatment for unruptured middle cerebral artery aneurysms: a systematic review and updated meta-analysis
Authors: Ferreira Marcio Yuri , Batista Savio , Oliveira Leonardo B. , Marques Guilherme Nunes , Maia Henrique Garcia , Palavani Lucca B. , Andreão Filipi Fim , Borges Pedro G. L. B. , Semione Gabriel , Sousa Marcelo Porto , Besborodco Raphael Muszkat , Bertani Raphael , Serulle Yafell , Ferreira Christian , Langer David
Published: August 2024

OBJECTIVE

Unruptured middle cerebral artery aneurysm (uMCAA) has traditionally been treated with open surgical clipping (SC). Endovascular treatments (EVTs) were designed to reduce surgical risks in these cases. Nevertheless, despite its potential benefits, many surgeons favor SC for uMCAA. This updated meta-analysis aimed to compare the safety, efficacy, and clinical outcomes of SC and EVT for uMCAA.

METHODS

The authors searched the Medline, Embase, and Cochrane Library databases according to the Cochrane and PRISMA guidelines. Eligible studies included those with ≥ 4 patients with uMCAA reporting comparative data of SC and EVT. The endpoints were the complete occlusion rate (Raymond class I and II), good clinical outcomes (modified Rankin Scale score ≤ 2 or Glasgow Outcome Scale score ≥ 4), procedure-related complications (further divided into major and minor), and mortality. The authors pooled OR with 95% CI values with a random-effects model. I2 statistics were used to assess heterogeneity, and sensitivity analysis was conducted to address high heterogeneity. Publication bias was assessed with funnel plot analysis and the Egger’s test.

RESULTS

The analysis included data from 10 studies. Regarding the complete occlusion assessment, the comparative analysis revealed OR 0.17 (95% CI 0.08–0.40, p < 0.01), favoring SC. In terms of achieving good clinical outcomes, OR 0.44 (95% CI 0.20–0.97, p < 0.05) was determined, favoring SC. No differences regarding total procedure-related complications, major complications, or mortality were identified. However, a higher likelihood of minor complications was identified for EVT, with OR 4.68 (95% CI 2.01–10.92, p < 0.01).

CONCLUSIONS

This systematic review and meta-analysis identified a lower likelihood of complete occlusion at last follow-up and lower likelihood of good clinical outcomes in patients treated with EVT when compared with SC. Furthermore, a higher likelihood of minor complications was identified in patients who underwent EVT when compared with SC. The findings reinforce that, based on the currently available data, SC should be considered the primary approach for treating uMCAA. However, EVT is an evolving approach, and this study’s findings represent a synthesis of observational studies. Randomized trials are warranted to elucidate which approach should be the mainstay for uMCAA and to identify the nuances that determine whether SC or EVT is more or less indicated for addressing uMCAA with consideration of the individuality of each patient and aneurysm.
Intracranial complications secondary to acute bacterial sinusitis requiring neurosurgical intervention before and after the onset of the COVID-19 pandemic
Authors: Flanders Tracy M. , Kumar Nankee K. , Zhao Chao , Joerger Torsten A. , Huh Jimmy W. , Buzi Adva , Rizzi Mark D. , Settoon Christine , Storm Phillip B. , Heuer Gregory G. , Kennedy Benjamin C. , Tucker Alexander M. , Madsen Peter J. , Lang Shih-Shan
Published: August 2024

OBJECTIVE

Intracranial complications of acute bacterial sinusitis are rare pathologies that occur in children, and are associated with significant neurological morbidity and mortality. There is a subjective concern among neurosurgeons that the incidence of this rare disease has increased since the onset of the novel COVID-19 pandemic. The primary objective of this study was to review the presentation and management of patients admitted at the authors’ institution with intracranial extension of sinusitis, to better understand the local disease burden relative to the COVID-19 pandemic.

METHODS

This is a single-center retrospective observational cohort study. The patients underwent neurosurgical intervention for intracranial extension of sinusitis between January 1, 2007, and March 1, 2023. The historical cohort was defined as those patients who presented prior to March 2020. Clinical covariates such as surgical and microbiological data were collected and analyzed.

RESULTS

A total of 78 patients (55 historical, 23 new) were included; they had a median age of 11.7 years and a male predominance of 69.2%. There was a significant increase in the annual rate of neurosurgical intervention for suppurative intracranial extension of acute bacterial sinusitis after the onset of the COVID-19 pandemic, with an average of 4.2 cases per year prior to March 2020 compared to 7.7 cases per year after that date (p = 0.013). This increase was largely driven by the unprecedented case volume of 13 cases in 2022. Patients in the new cohort were older (p = 0.009) and more likely to have Pott’s puffy tumor/frontal bone osteomyelitis (p = 0.003) at the time of presentation than patients in the historical cohort. Patients in the new cohort had lower rates of readmission within 30 days of discharge than those in the historical cohort (p = 0.047). In both cohorts, patients with seizure on presentation were more likely to have neurological sequelae at last follow-up (p = 0.004), which occurred at a median of 2.9 months after discharge.

CONCLUSIONS

Clinicians encountering pediatric patients presenting with persistent symptoms of acute bacterial sinusitis must have a high index of suspicion for suppurative intracranial extension. Prompt neuroimaging and subsequent neurosurgical intervention are critical to ensure timely diagnosis and treatment. The results in this study show a significant increase in the number of neurosurgical interventions for suppurative intracranial extension of sinusitis per year after the onset of the COVID-19 pandemic. Further research is needed to understand the underlying pathophysiology of this clinical phenomenon.
The effect of birth type and gender on growth performance, live weight gain, growth pattern modeling, and survival rate in Anatolian Merino lambs
Authors: Boğa Kuru Buket , Ölmez Veli
Published: August 2024

In this study, the aim was to determine the effect of birth type and gender on growth performance, live weight gain, growth modeling, and survival rate in Anatolian Merino lambs. Growth performance was determined in 28 singletons (14 females/14 males), 80 twins (38 females/42 males), and 54 triplets (22 females/32 males) lambs in the study. The body weight of the lambs was measured on the day of birth (day 0), and at 10, 20, 30, 45, and 60 days of age. Birth type was effective on growth performance in Anatolian Merino lambs (P
INFORMATION SYSTEM FOR DATA PROCESSING IN SPORTS USING THE RANDOM FOREST METHOD
Authors: KUNANETS Nataliia , ZHMURKEVYCH Orest
Published: August 2024

A huge amount of data is collected and generated in modern sports. This data can be used to improve athletes' performance, make more informed coaching and strategic decisions, and increase fan engagement. However, processing, analyzing, and interpreting this data can be challenging. This article is devoted to the development of an information system for data processing in the sports sector using the random forest method. The system aims to ensure efficient collection, processing, and analysis of large amounts of data generated during sports competitions, training, and interaction with fans and other stakeholders.
Research methods. This article proposes an information system (IS) for data processing in the sports industry using the Random Forest (RF) method. As one of the machine learning methods, it is well suited for working with large amounts of data and complex classification and prediction tasks. The proposed IS consists of three main components. The data collection module accumulates data from various sources such as sensors, GPS trackers, websites, and social networks. The data processing module cleans, normalizes, and transforms the data to prepare it for analysis. The data analysis module uses the RF method to analyze data, predict outcomes, identify patterns, and make decisions.
The conducted research has shown that the proposed IS can be an effective tool for predicting the results of sports competitions with high accuracy, identifying patterns in the data that can be useful for coaches and athletes to improve their training and strategy, personalizing training programs and recommendations for athletes, increasing the level of fan engagement by providing them with personalized content and forecasts.
The proposed IS based on the random forest method is a powerful tool for processing and analyzing data in the sports industry. Its use can lead to improved athletes' performance, more informed coaching and strategic decisions, and increased fan engagement.
One of the most powerful and accurate machine learning methods, the random forest method, allows for reliable analysis and forecasting based on various types of data, including player statistics, match results, physiological indicators, and fan behavior data. The article describes the stages of creating an information system: from data collection to data processing, storage, and analysis.
ПРОБЛЕМАТИКА КОНВЕРГЕНЦІЇ МЕРЕЖЕВОЇ ІНФРАСТРУКТУРИ УКРАЇНИ ТА ЄС: ІНДЕКС ЦИФРОВОЇ ЕКОНОМІКИ ТА СУСПІЛЬСТВА
Authors: ЛІСКЕВИЧ Олег , ОБЕЛЬОВСЬКА Квітослава , АБЗЯТОВ Андрій , ЛІСКЕВИЧ Ростислав
Published: August 2024

Мережева інфраструктура є основою для ефективного функціонування сучасної цифрової економіки. Успіх української економіки додатково залежить від сумісності її мережевої інфраструктури з мережевою інфраструктурою ЄС. Тому важлвою є задача аналізу станів мережевої інфраструктури ЄС та України з метою виявлення об визначити викликів, які Україні потрібно буде подолати на шляху конвергенції української цифрової економіки з цифровою економікою ЄС. Актуальність роботи обґрунтовується тим, що впровадження передових цифрових мережевих технологій, узгоджених з європейськими, є одним із шляхів підвищення майбутньої конкурентоспроможності української економіки.
Індекс цифрової економіки та суспільства (DESI) узагальнює низку показників ефективності цифрових технологій у Європі та дозволяє оцінити стан цифрової економіки та суспільства. Ця робота присвячена аналізу одного з індикаторів DESI, а саме цифрової інфраструктури, як в Європейському Союзі (ЄС), так і в Україні. Аналіз охоплює цифрові інфраструктури визначені DESI 2023, такі як щонайменше 100 Мбіт/с фіксованого широкосмугового зв’язку, щонайменше 1 Гбіт/с широкосмугового зв’язку, фіксоване покриття мереж дуже високої пропускної здатності (VHCN), оптоволокно до приміщення (FTTP), використання мобільного широкосмугового зв’язку, покриття 5G.
Аналіз показав, що Україна на біжучий момент має добрий стан з впровадженням технології FTTP, і, відповідно, вона  може стати основою для конвергенції цифрової інфраструктури України та ЄС. Проте, згідно з нашим аналізом, Україні терміново необхідно прискорити впровадження мереж 5G, яка сприятиме модернізації та відновленню національної економіки. Результати аналізу будуть корисними для зближення цифрової економіки України з європейською цифровою економікою.
OPTIMIZATION OF CYBER-PHYSICAL SYSTEM PARAMETERS BASED ON INTELLIGENT IOT SENSORS DATA
Authors: ZASORNOVA Iryna , FEDULA Mykola , RUDYI Andrii
Published: August 2024

The optimization of cyber-physical systems (CPS) parameters is researched with focusing on the integration of computation, networking, and physical processes with the Internet of Things (IoT). The use of intelligent IoT sensors is crucial for collecting real-time data, which is necessary for enhancing the efficiency, reliability, and performance of CPS.
Various methods of CPS parameters optimization are analyzed and categorized into model-based approaches, data-driven approaches, and hybrid approaches. The model-based approaches rely on mathematical models to describe CPS behavior and use optimization algorithms like linear programming and evolutionary algorithms to predict system responses and optimize parameters. But, the limitations of model-based approaches are related to complex systems with uncertain or dynamic behavior. The data-driven approaches are more suitable for complex cyber-physical systems. These approaches utilize machine learning and data analytics techniques to extract patterns from sensor data, which are then used to adjust system parameters. The hybrid approaches combine elements of both model-based and data-driven methods.
The method of cyber-physical system parameters optimization based on intelligent IoT sensors data processing is developed with using of distributed neural network. The optimization problem is formulated with constraints for the system parameters. The neural network mathematical model and learning algorithm are proposed.
The performed research shows the importance of developing optimization methods for CPS parameters based on intelligent IoT sensor data, considering the evolving nature of IoT technology. The integrating intelligent sensors into CPS offers new opportunities for optimizing system performance but also presents challenges in data management and security that should be addressed in future.
PENGARUH LINGKUNGAN KERJA, KOMPENSASI, DISIPLIN KERJA, BEBAN KERJA, DAN WORK LIFE BALANCE TERHADAP KEPUASAN KERJA KARYAWAN PADA MEGA FINANCE CABANG JEMBER
Authors: Susanti Susi , Widagdo Suwignyo , Dahliani Yani
Published: August 2024

This research aims to determine and analyze the influence of Work Environment, Compensation, Work Discipline, Work Load, and Work Life Balance on Employee Satisfaction at Mega Finance Jember branch. This type of research is associative which aims to determine the influence or relationship between two or more variables. The number of respondents was 34 people. The analytical tool used is multiple linear regression (SPSS Version 25). The research results show that Work Environment, Compensation, Work Discipline and Work Life Balance have a positive and significant effect on Employee Job Satisfaction at Mega Finance Jember branch and Workload has a negative and significant effect on Employee Job Satisfaction at Mega Finance Jember branch. To increase employee job satisfaction at the Jember branch of Mega Finance, namely by creating a positive work environment, the company must provide fair compensation, encourage strong work discipline, manage workload effectively, and support work life balance to achieve company goals.
PENGARUH WORD OF MOUTH, BRAND IMAGE, HARGA, KEBERAGAMAN PRODUK DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN PADA NESYA DRINK
Authors: Yuliana Yuliana , Widagdo Suwignyo , Hari Prastyowati Agustin
Published: August 2024

The research aims to determine the influence of Word of Mouth, Brand Image, Price, Product Diversity and Product Quality partially and simultaneously on Nesya Drink Purchasing Decisions. This research is a type of research that uses quantitative research methods. The sampling technique used in this research was purposive sampling. The data analysis methods used are Validity Test, Reliability Test, Normality Test, Multicollinearity Test, Heteroscedasticity Test. The Product Quality variable has a significant effect on the Purchasing Decision variable.
Dynamics of a ratio-dependent three-species food-chain system in a random environment
Authors: Shi Peilin , Dong Lingzhen
Published: August 2024

We consider a system of stochastic differential equations, which is established by introducing white noises into a periodic and ratio-dependent food-chain system of three-species. We investigate the asymptotic behaviors for such a system, and obtain the sufficient conditions for its extinction and persistence with the help of Itô’s formula. We discuss the existence of a nontrivial positive periodic solution based on Has’minskii theory of periodic solution. Further, we study a ratio-dependent food-chain system of three-species including not only white noise but also telephone noise. For such a model, we give the sufficient conditions to guarantee the existence of a unique ergodic stationary distribution.
Magnetic Kirchhoff–Schrödinger equations with critical exponential growth and indefinite potential in R 2
Authors: Li Qingyue , Cheng Xiyou , Yang Lu
Published: August 2024

In this paper, we are concerned with the following magnetic nonlinear equation of Kirchhoff type with critical exponential growth and an indefinite potential in R 2 m ( ∫ R 2 [ | 1 i ∇ u − A ( x ) u | 2 + V ( x ) | u | 2 ] d x ) [ ( 1 i ∇ − A ( x ) ) 2 u + V ( x ) u ] = B ( x ) f ( | u | 2 ) u , where u ∈ H 1 ( R 2 , C ), m is a Kirchhoff type function, V : R 2 → R and A : R 2 → R 2 represent locally bounded potentials, while B denotes locally bounded and f exhibits critical exponential growth. By employing variational methods and utilizing the modified Trudinger–Moser inequality, we get ground state solutions or nontrivial solutions for the above equation. Furthermore, in the special case where m is a constant equal to 1, the equation is reduced to the following magnetic nonlinear Schrödinger equation, ( 1 i ∇ − A ( x ) ) 2 u + V ( x ) u = B ( x ) f ( | u | 2 ) u in  R 2 . Applying analogous methods, we can also establish the existence of ground state solutions or nontrivial solutions to this equation.
Parkinson’s Disease and Other Alzheimer’s Disease and Related Dementia Pathologies and the Progression of Parkinsonism in Older Adults
Authors: Buchman Aron S. , Yu Lei , Oveisgharan Shahram , Zammit Andrea R. , Wang Tianhao , Shulman Joshua M. , VanderHorst Veronique , Nag Sukrit , Bennett David A.
Published: August 2024

Background: The interrelationship of parkinsonism, Parkinson’s disease (PD) and other Alzheimer’s disease (AD) and Alzheimer’s disease and related dementias (ADRD) pathologies is unclear. Objective: We examined the progression of parkinsonian signs in adults with and without parkinsonism, and their underlying brain pathologies. Methods: Annual parkinsonian signs were based on a modified Unified Parkinson’s Disease Rating Scale. We used linear mixed effects models to compare the progression of parkinsonian signs in 3 groups categorized based on all available clinical evaluations: Group1 (never parkinsonism or clinical PD), Group2 (ever parkinsonism, but never clinical PD), Group3 (ever clinical PD). In decedents, we examined the progression of parkinsonian signs with PD and eight other AD/ADRD pathologies. Results: During average follow-up of 8 years, parkinsonian signs on average increased by 7.3% SD/year (N = 3,807). The progression of parkinsonian signs was slowest in Group1 (never parkinsonism or clinical PD), intermediate in Group2, and fastest in Group3. In decedents (n = 1,717) pathologic PD and cerebrovascular (CVD) pathologies were associated with a faster rate of progressive parkinsonian signs (all p values <0.05). However, pathologic PD was rare in adults without clinical PD (Group1, 5%; Group2, 7% versus Group3, 55%). Yet, 70% of adults in Group2 without pathologic PD showed one or more CVD pathologies. In Group2, adults with pathologic PD showed faster progression of parkinsonian signs compared with those without evidence of pathologic PD and their rate of progression was indistinguishable from adults with clinical PD. Conclusions: Parkinsonism in old age is more commonly related to cerebrovascular pathologies relative to pathologic PD and only a minority manifest prodromal PD.
Meeting Report: 2023 Muscular Dystrophy Association Summit on ‘Safety and Challenges in Gene Therapy of Neuromuscular Diseases’
Authors: Lek Angela , Atas Evrim , Lin Brian , Hesterlee Sharon E. , Abbott Jordan K. , Byrne Barry J. , Bönnemann Carsten G.
Published: August 2024

This meeting report summarizes the presentations and discussions held at the summit on Challenges in Gene Therapy hosted by the Muscular Dystrophy Association (MDA) in 2023. Topics covered include safety issues, mitigation strategies and practical considerations pertaining to the clinical translation of gene therapies for neuromuscular disease. The listing of actionable recommendations will assist in overall efforts in the field to achieve safe and efficacious translation of gene therapies for neuromuscular disease patients.
DeepOnto: A Python package for ontology engineering with deep learning
Authors: He Yuan , Chen Jiaoyan , Dong Hang , Horrocks Ian , Allocca Carlo , Kim Taehun , Sapkota Brahmananda
Published: August 2024

Integrating deep learning techniques, particularly language models (LMs), with knowledge representation techniques like ontologies has raised widespread attention, urging the need of a platform that supports both paradigms. Although packages such as OWL API and Jena offer robust support for basic ontology processing features, they lack the capability to transform various types of information within ontologies into formats suitable for downstream deep learning-based applications. Moreover, widely-used ontology APIs are primarily Java-based while deep learning frameworks like PyTorch and Tensorflow are mainly for Python programming. To address the needs, we present DeepOnto, a Python package designed for ontology engineering with deep learning. The package encompasses a core ontology processing module founded on the widely-recognised and reliable OWL API, encapsulating its fundamental features in a more “Pythonic” manner and extending its capabilities to incorporate other essential components including reasoning, verbalisation, normalisation, taxonomy, projection, and more. Building on this module, DeepOnto offers a suite of tools, resources, and algorithms that support various ontology engineering tasks, such as ontology alignment and completion, by harnessing deep learning methods, primarily pre-trained LMs. In this paper, we also demonstrate the practical utility of DeepOnto through two use-cases: the Digital Health Coaching in Samsung Research UK and the Bio-ML track of the Ontology Alignment Evaluation Initiative (OAEI).
Urinary opioid peptides in children with autism spectrum disorders. A Pilot Study
Authors: Tveiten Dag , Bryn Vesna , Saugstad Ola Didrik , Isaksen Jørn , Rønning Per Ola , Skjeldal Ola H.
Published: August 2024

BACKGROUND: Circulating β-casomorphins (BCM) and gluten exorphins (GE), which are exogenous opioid peptides originating from bovine milk protein casein and cereal protein gluten, respectively, have been proposed as potential trigger factor to symptoms observed in children with autism. OBJECTIVE: Given the debate surrounding the detectability of these opioid peptides in body fluids, particularly using highly sensitive and specific mass spectrometry (HPLC-MS) techniques, we aimed to investigate their presence in urine samples of autistic subjects. METHODS: We employed an HPLC-MS method for peptide detection. RESULTS: The presence of several BCMs and GEs in the urine of both autistic children (ASD) and healthy controls (HC) was documented. The detection of dietary opioid peptides even at very low concentrations underscores the sensitivity of this novel HPLC-MS method. BCM-8 was more often detected in the ASD group compared to the HC group. A higher prevalence of gastrointestinal (GI) symptoms were also observed in the ASD group. CONCLUSIONS: This pilot study supports the presence of BCMs and GEs in urine samples in subjects with autism as well as healthy controls which was the main goal of this pilot study. Prolonged exposure to bovine BCMs and GEs may play a role in the manifestation of core and GI symptoms in subgroups of autism. Further research is warranted to investigate this phenomenon thoroughly.
Enhancing physiotherapy department design to prevent work-related musculoskeletal disorders: Vision of future research
Authors: Kakaraparthi Venkata Nagaraj , Gannamaneni Vamsi Krishna , Reddy Ravi Shankar , Alahmari Khalid A. , Tedla Jaya Shanker , Alshahrani Mastour Saeed
Published: August 2024

BACKGROUND: The increasing prevalence of work-related musculoskeletal disorders (WRMSDs) necessitates a reevaluation of physiotherapy department design. Optimizing these spaces is crucial as they serve as primary settings for preventing and managing WRMSDs, highlighting the need for a forward-thinking approach. OBJECTIVE: This study aims to outline a vision for future research by identifying key strategies to prevent WRMSDs and enhance operational efficiency in physiotherapy departments. METHODS: Ergonomics, workplace safety, and physiotherapy practices formed the basis for this paper in identifying the current challenges and opportunities in departmental design. Expert insights and feedback from healthcare practitioners aiding in the formulation of innovative solutions and recommendations for future research endeavors. RESULTS: Integration of ergonomic principles, advanced technologies, interdisciplinary collaboration, and proactive safety measures into physiotherapy department design improve working environments for physiotherapists. CONCLUSION: Envisioning the future of physiotherapy department design offers promising avenues for improving patient care outcomes and supporting therapist well-being.
COVID-19 Vaccine Effectiveness Against Long-COVID-19 Condition in Pakistan
Authors: Ali Asma Sabir , Baig Fraz Ahmed , Channa Siraj Ahmed , Kumar Sooraj , Adnan FNU , Ashraf Amna , Najam Ali , Akhtar Waheed , Malik Jahanzeb
Published: August 2024

OBJECTIVE: The objective of this study was to analyze the demographic characteristics, vaccination timing, and associated factors influencing the persistence or onset of long-COVID-19 symptoms among patients.

METHODS: Data were collected anonymously from the Abbas Institute of Medical Sciences, with patients required to meet specific criteria, including having encounters with healthcare providers both before and after January 1, 2023. Patients diagnosed with COVID-19 were identified using ICD-9 or ICD-10 codes or positive test results. Long-COVID-19 cases were defined as those exhibiting symptoms 12-20 weeks post-diagnosis. Logistic regression and general linear models were employed to identify factors influencing long-COVID-19 outcomes, considering vaccination timing and demographic characteristics.

RESULTS: The analysis involved 3,140 patients diagnosed with long-COVID-19. Results revealed significant associations between demographic characteristics and long-COVID-19 outcomes. Males exhibited higher odds compared to females, with younger age groups and individuals of Punjabi ethnicity showing increased odds of experiencing long-COVID-19 symptoms. However, no significant association was found between vaccination status and long-COVID-19 outcomes. Logistic regression analysis showed varying odds ratios associated with vaccination timing post-diagnosis, with notable increases observed within 0-4 weeks and 4-8 weeks post-diagnosis. The general linear model further confirmed these associations, highlighting the significance of age, gender, ethnicity, and comorbidities in predicting long-COVID-19 outcomes.

CONCLUSION: The study underscores the importance of demographic factors and vaccination timing in understanding and predicting long-COVID-19 outcomes. These findings can inform targeted interventions and healthcare strategies aimed at mitigating the impact of long-COVID-19 and improving patient care and management. Further research is warranted to explore additional factors contributing to long-COVID-19 and to validate these findings in larger and more diverse populations.
Vzniká globální občanská společnost? Nestátní aktéři ve světové politice
Authors: Císař Ondřej
Published: August 2024

Cílem této stati je odpovědět na otázky, které byly formulovány v souvislosti s rostoucím významem nevládních organizací a sociálních hnutí ve světové politice. Základní otázkou, kterou tento text klade, je: Dochází skutečně ke konstituci globálních struktur občanského aktivismu? Jinými slovy řečeno, konstituuje se v souvislosti s rozvojem globálních politických struktur globální občanská společnost? Pokud ano, jak se tato globální občanská společnost vztahuje k lokálním aktérům? Funguje jako partner pomáhající při budování lokálního aktivismu? A jakým způsobem se aktéři globální občanské společnosti dotýkají postavení států? Překonávají jejich omezení? Proto, aby mohly být tyto otázky zodpovězeny, stať nejprve mapuje diskuzi, která se kolem transnacionálních vztahů rozvinula. Problematika transnacionálních vztahů se během posledního desetiletí konstituovala jako významný výzkumný problém v rámci nejméně dvou sociálně-vědných disciplín - v teorii mezinárodních vztahů a v teorii kolektivního jednání. Pozornost věnovaná transnacionálním hnutím a sítím nevládních organizací navíc podstatným způsobem ovlivnila diskuzi v určitých oblastech politické teorie, kde se tato hnutí pod výše uvedeným označením globální občanská společnost stala ztělesněním reformních nadějí vkládaných do globálně koordinovaného občanského aktivismu, jenž by měl v konečném důsledku přispět ke světové demokratizaci a k realizaci sociální spravedlnosti. V tomto smyslu jde o interdisciplinární problém a význam jeho studia může být v různých disciplínách různý. Hlavním cílem stati je odpovědět na výše uvedené otázky. Stať se proto snaží reflektovat nejdůležitější problémy diskuze o transnacionálním politickém jednání. Její ambicí je zahrnout jak více empiricky orientované přístupy, tak i normativně motivované úvahy o demokratizačním potenciálu transnacionálních hnutí v současné fázi vývoje moderní společnosti, tj. ve fázi tzv. globalizace. Základní argument stati tvrdí, že koncept globální občanské společnosti je do určité míry použitelný k popisu politického jednání "vně státních hranic", pokud jej však nechápeme v silném smyslu jako pojem popisující alternativu k institucím národních států a pokud jej zbavíme jeho ideologické náplně.
ANALISIS POSITIONING TAKOYAKI IS FUM DI DAERAH ISTIMEWA YOGYAKARTA
Authors: Seno Nurrohman Aryo , Chasanah Uswatun
Published: August 2024

Penelitian ini bertujuan untuk mengetahui bagaimana positioning brand Takoyaki Is Fum di Daerah Istimewa Yogyakarta. Atribut - atribut produk yang dijadikan sebagai variabel penelitian meliputi rasa, lokasi usaha, harga, pelayanan, kemasan, waktu tunggu, keramahan, tempat makan, kebersihan, dan kelengkapan produk. Penelitian ini dilakukan dengan menggunakan metode survey melalui proses pengisian kuesioner. Instrumen telah diuji validasi dan reliabilitasnya dengan menggunakan SPSS. Populasi yang digunakan dalam penelitian ini adalah masyarakat di Daerah Istimewa Yogyakarta yang setidaknya pernah satu kali membeli takoyaki yang kemudian diambil sebagai sampel sebanyak 100 responden. Data yang diperoleh kemudian diolah dengan SPSS teknik Multidimensional Scalling (MDS). Peta persepsi menunjukan bahwa merek De’Takoyaki Pakuwon Mall memiliki keunggulan pada atribut tempat makan. Sedangkan pada merek Takoyaki Kurisupi dipandang tidak memiliki keunggulan pada atribut-atribut yang telah ditentukan. Disisi lain, merek Takoyaki Disini, Takoyaki Klebengan dan Takoyaki Peko-Peko dianggap sama - sama memiliki keunggulan di atribut harga. Selanjutnya untuk merek Takoyaki Is Fum dipandang memiliki keunggulan di beberapa aspek yaitu aspek rasa, lokasi, pelayanan, waktu tunggu, keramahan, kebersihan, kemasan dan kelengkapan produk jika dibandingkan dengan merek lainnya. Dapat disimpulkan bahwa berdasarkan atribut- atribut yang telah ditentukan, merek Takoyaki Is Fum paling banyak diminati dibanding dengan merek lainnya.
Perceived inflation in the Vietnamese economy: New points in methodology and applications
Authors:   University of Economics and Law, VNU-HCM, Vietnam, Thị Phạm Thanh Xuân , Thị Nguyễn Cành ,   University of Economics and Law, VNU-HCM, Vietnam, Hữu Hồ Tín ,   University of Economics and Law, VNU-HCM, Vietnam
Published: August 2024

Researching and developing methods to measure perceived inflation is an indispensable requirement for the monetary policy management of the State Bank of Vietnam, especially in the context of interest rate amplitudes. remains at the lowest level in history in Vietnam. This study was conducted in that context with the goal of developing a tool to measure perceived inflation based on a solid methodological foundation. The result is the creation of a new measure, integrating the psychological 'gain-loss' effect of consumers on price fluctuations. In particular, the final product is an integrated website, allowing automation of the research and analysis process. The results of the study provide evidence of overstated consumer inflation perceptions during periods of economic volatility, when perceived inflation is significantly higher than the headline inflation (CPI). These findings not only have academic value but are also important in supporting the State Bank of Vietnam in evaluating and operating monetary policy, especially in identifying and dealing with fluctuations in perceived inflation in the economy. From the results of this study, we call for participation and suggestions from the experts, with the aim of minimizing the undesirable effects of inflation and supporting the maintenance of a stable inflation rate, contributing to Vietnam’s economic growth in 2024.
Eigentlich eindeutig! Erreichbarkeit und Ansprechbarkeit des Jugendamtes im Kinderschutz – Zur Rolle und den Aufgaben öffentlicher und freier Träger der Kinder- undJugendhilfe im Rahmen der Inobhutnahme
Authors: Trenczek Thomas
Published: August 2024

Der Beitrag erläutert und kommentiert zunächst die wesentlichen gesetzlichen Regelungen zu den Aufgaben und Befugnissen sowie dem Verhältnis der verschiedenen Akteur*innen im Bereich der Inobhutnahme nach § 42 SGB VIII. Hierbei soll insb. auch die Bedeutung von 24h-Bereitschaftsdiensten im Jugendamt (ASD) deutlich werden.
Alternativ Denken: Menschen auf der Flucht sind „Displaced Persons“ – ein Zwischenruf!
Authors: Kunstreich Timm
Published: August 2024

In dem folgenden Beitrag wird an die Idee eines anderen Denkens über und Handelns mit geflüchteten Menschen und zugleich an Louis Lowy erinnert. Lowy war ein jüdischer Sozialarbeiter und einer der ‚Erfinder‘ der Sozialen Gruppenarbeit, die er im KZ Theresienstadt, so lässt es sich nachträglich deuten, als methodisches Bildungs- und (Selbst-)Erziehungs-Setting entwickelte.
ШЛЯХИ ФОРМУВАННЯ ПРОПОЗИЦІЇ НА РИНКУ В’ЇЗНОГО ВОЄННОГО ТУРИЗМУ В УКРАЇНІ
Authors: Щука Галина , Журба Ігор , Коробейникова Ярослава
Published: August 2024

Статтю присвячено актуальним питанням формування пропозиції на ринку в’їзного воєнного туризму в Україні. Визначено сутнісні характеристики даного виду туризму та його ресурсну базу, встановлено основні терміни, які використовуються для означення даного виду подорожей, в результаті порівняння доведено, що об’єднуючим поняттям є «воєнний туризм». Переглянуто та доповнено розуміння структури даного сегменту туристичного ринку. Досліджено можливості розвивати воєнний туризм в Україні до закінчення російсько-української війни. Встановлено перелік областей, де за рахунок їхнього прикордонного положення, високого рівня безпечності території та наявних туристичних ресурсів доцільно формувати меморіальні, волонтерські, пізнавальні, пригодницько-розважальні та подієві тури для іноземців; зосередитися над розвитком солідарного туризму, де продукти воєнного туризму пропонувати як додаткові послуги.
Variation of the nutritional content of different genotypes of Lotus corniculatus L. under optimum and sub-optimal soil moisture conditions throughout the seasons of the year
Authors: Xolocotzi-Acoltzi Sahara , Pedroza Sandoval Aurelio , Trejo-Calzada Ricardo , García-De los Santos Gabino , Yáñez-Chávez Luis G.
Published: August 2024

O
Objective: To evaluate the leaf nutrient content of four accessions and one variety of Lotus corniculatus L. trefoil throughout the seasons of the year and under optimum and sub-optimal soil moisture content, established under a shade mesh in northern Mexico.
Design/Methodology/Approach: During the 2021-2022 period, an experimental randomized block design, in a split-plot arrangement, with three replicates was established. The large plots had an optimum (26±1.5%) and sub-optimal (22±1.5%) soil moisture content. The small plots consisted of the trefoil accessions: 255301, 255305, 202700, 226792 origin code, and the Estanzuela Ganador variety.
Results: At optimum soil moisture content, the 202700 accessions recorded a K deficiency throughout the year. Meanwhile, regardless of the soil moisture content, the 255301 accessions recorded a Mg and a Mn deficiency only in summer. N, P, Fe, and Mn recorded deficient contents: N and P throughout the year and Fe and Mn only in winter and spring.
Study Limitations/Implications: These results could require a field validation, since the experiment was carried out in semi-controlled conditions, under shade mesh.
Findings/Conclusions: Developing an adequate annual nutrition program for L. corniculatus L. that improves its forage productivity requires several key factors, including the behavior of the nutritional status (dependent on the type of nutrient), the growth stage of the plant, the season of the year, and the soil moisture content.
Natural regeneration of white mangrove (Laguncularia racemosa L.) during the dry season in Ejido La solución in Paraíso, Tabasco, México
Authors: Sánchez-Díaz Baltazar , Sol Sánchez Ángel , Hernández Melchor Gloria Isela , Geron Cano Hugo Eduardo , Zaldivar-Cruz Juan M.
Published: August 2024

Objective: To estimate the natural regeneration and growth in the sapling stage of white mangrove during the dry season.
Design/methodology/approach: Measurements of the structural variables of white mangrove, diameter at breast height (DBH), height and crown diameter were made in three sampling plots. A statistical analysis was performed with the data obtained and mean data were obtained from the three sampling plots.
Results: DBH data were 0.34, 0.37 and 0.42 m; height 1.34, 1.28 and 1.58 m; and crown 44.18, 38.56 and 39.83 cm, in each sampling plot respectively.
Limitations on study/implications: In dry seasons, erosion can expose rocky or sandy substrates that are not suitable for mangrove growth.
Findings/conclusions: The white mangrove in its sapling stage during the dry season, presented statistically significant differences in growth between sampling plots using the dasometric variables (DBH, height and crown diameter).