bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Low-Dose Colchicine on Serum High-Sensitivity C-Reactive Protein Level in Coronary Artery Disease Patients with Type 2 Diabetes Mellitus and Enhanced Inflammatory Response Protocol for a Randomized, Double-Blind, Placebo-Controlled, Phase 2, Dose-Finding Study
Authors: Miwa Yoshikazu , Mutoh Akiko , Morimoto Takeshi , Ikehara Yumi , Yasu Takanori , Koba Shinji , Ako Junya , Higashi Yukihito , Kajikawa Masato , Uehara Hiroki , Ishikawa Kazuo , Sakuma Ichiro , Tomiyama Hirofumi , Node Koichi , Kumagai Yuji , Ueda Shinichiro
Published: December 2022

Although cardiovascular mortality in Japan is lower than in other industrialized countries, clinical outcomes in coronary artery disease (CAD) patients with type 2 diabetes mellitus (T2DM) remain poor despite multiple evidence-based drug therapies and interventions. We assumed that part of residual risk in these patients may be attributable to enhanced inflammation, which can be inhibited presumably by colchicine. However, dose-responsiveness of anti-inflammatory effect of colchicine has not been elucidated. Therefore, we designed a multicenter, randomized, double-blinded, parallel-group study to explore the dose-dependent effects of low-dose colchicine on serum high-sensitivity C-reactive protein (hs-CRP) concentration and safety in CAD patients with T2DM and enhanced inflammatory response as a phase 2 study. Enhanced inflammatory response was defined as peripheral white-blood cell count ≥7,000/μL. Patients (N = 63) will be randomly assigned to two doses of colchicine 0.25 mg/day, 0.5 mg/day, or placebo in a 1:1:1 ratio once daily for 12 weeks. Changes in serum hs-CRP levels will be evaluated as the primary endpoint, and changes in flow-mediated vasodilation and plasma myeloperoxidase levels will be evaluated as secondary endpoints. The results of this study will contribute to the development of a protocol for a planned future phase 3 trial to estimate the reduction in CAD. The present study describes the rationale, design, and methods of the trial.
Influence of Cardiovascular Risk Factors in Early Relapsing-Remitting Multiple Sclerosis: A Retrospective Analysis
Authors: Arroyo-Pereiro Pablo , Muñoz-Vendrell Albert , Bau Laura , Matas Elisabet , Romero-Pinel Lucia , Martínez-Yélamos Antonio , Martínez-Yélamos Sergio
Published: December 2022

Introduction: Prior studies have suggested that cardiovascular risk factors (CVRFs) can affect the prognosis of multiple sclerosis (MS). The aim of this study was to assess if CVRFs affect the early course of MS. Methods: A retrospective observational study was performed, including patients diagnosed with relapsing-remitting MS (RRMS) from 2010 to 2020, with at least 2 years of disease and 6 months follow-up. Age at onset, disease duration, number of relapses, time to confirmed Expanded Disability Status Scale (EDSS) 3.0 and 6.0, and time to secondary progressive MS (SPMS) were collected. Presence and date at onset of hypertension (HT), diabetes mellitus (DM), high low-density lipoprotein cholesterol (LDLc), and smoking during the study period were collected. The primary objective was to assess if CVRFs at the onset of MS are associated with lower time to EDSS 3.0, time to EDSS 6.0, and time to SPMS, using bivariate and multivariate analysis. Results: 281 RRMS patients were included; median age at onset was 33 (IQR 26–39); 69.4% were female. Median EDSS at onset was 1.5 (IQR 1–2.5). Nine patients reached SPMS; 24 patients were diagnosed with HT, 9 with DM, 109 with high LDLc, and 123 were smokers during follow-up. No statistically significant association was found between the presence of CVRF at MS onset and the mentioned clinical outcomes during the MS course. Conclusion: No association was found between CVRFs and the early course of MS in our cohort.
Successful Dasatinib Treatment of Epidermal Growth Factor Receptor-Mutant Lung Adenocarcinoma and BCR-ABL1-Positive Chronic Myeloid Leukemia: A Case Report
Authors: Tsukaguchi Akihiro , Minami Seigo , Yasuoka Hironao , Kin Yoshihiro
Published: December 2022

Dasatinib, a second-generation BCR-ABL1 tyrosine kinase inhibitor (TKI), inhibits multiple kinase pathways and is a promising anti-tumor agent for various solid tumors, including lung cancer. Herein, we report a patient with coexisting epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma and BCR-ABL1-positive chronic myeloid leukemia (CML). The patient received afatinib for a postoperative intrapulmonary recurrence of lung adenocarcinoma harboring EGFR exon 19 deletion. Tumor reduction was achieved with afatinib; however, dose reduction was required because of grade 2 diarrhea and skin toxicity. The reduced dose maintained a partial response. Thirty-one months after introduction of afatinib, he was diagnosed as having BCR-ABL1-positive CML and nilotinib was added to his treatment regimen. However, the combination of nilotinib and afatinib aggravated his diarrhea, prompting discontinuation of afatinib. Because nilotinib does not have sufficient anti-tumor efficacy for CML, dasatinib was substituted for nilotinib. Thirty-five months after introduction of dasatinib, bosutinib was substituted for dasatinib because of uncontrollable pleural effusions. Dasatinib achieved 31- and 35-month progression-free survivals for CML and EGFR-mutant lung adenocarcinoma, respectively. Dasatinib is thus a therapeutic option for coexisting EGFR-mutant lung adenocarcinoma and BCR-ABL1-positive CML when TKI combination therapy is contraindicated by severe adverse events. In our patient, adding nilotinib to afatinib led to severe diarrhea. When administering TKI combination therapy, drug-drug interactions should be considered.
Ischemic Optic Neuropathy Secondary to Varicella-Zoster Vasculitis Mimicking Giant Cell Arteritis: Case Report
Authors: Rodriguez-Pla Alicia , Grill Marie F. , Fletcher Geoffrey P. , Di Nome Marie A.
Published: December 2022

Differentiating GCA from its many mimickers remains a challenge in the daily clinical practice, especially in patients presenting with unspecific manifestations. We present the case of an 82-year-old woman who presented with a 3-week history of left eye vision loss secondary to bilateral edema and hemorrhage of the optic discs. Despite negative bilateral temporal artery biopsies, the elevation of the inflammatory markers and brain MRA findings suggestive of temporal arteritis as well as stenosis of the basilar artery led us to initiate treatment with high-dose steroids. Inflammatory markers remained elevated despite high-dose steroids which prompted additional work leading to a diagnosis of varicella-zoster encephalitis. Steroid treatment was quickly tapered off and treatment with acyclovir resulted in the normalization of the acute phase reactants. The persistence of elevated inflammatory markers despite high-dose steroids should prompt additional work up for the search of an alternative diagnosis of GCA mimickers.
Using Smartphone TechnolOGy to Support an EffecTive Home ExeRcise Intervention to Prevent Falls amongst Community-Dwelling Older Adults: The TOGETHER Feasibility RCT
Authors: Hawley-Hague Helen , Tacconi Carlo , Mellone Sabato , Martinez Ellen , Yang Fan , Su Ting-li , Chiari Lorenzo , Helbostad Jorunn L. , Todd Chris
Published: December 2022

Introduction: Falls have major implications for quality of life, independence, and cost of health services. Strength and balance training has been found to be effective in reducing the rate/risk of falls, as long as there is adequate fidelity to the evidence-based programme. The aims of this study were to (1) assess the feasibility of using the “Motivate Me” and “My Activity Programme” interventions to support falls rehabilitation when delivered in practice and (2) assess study design and trial procedures for the evaluation of the intervention. Methods: A two-arm pragmatic feasibility randomized controlled trial was conducted with five health service providers in the UK. Patients aged 50+ years eligible for a falls rehabilitation exercise programme from community services were recruited and received either (1) standard service with a smartphone for outcome measurement only or (2) standard service plus the “Motivate Me” and “My Activity Programme” apps. The primary outcome was feasibility of the intervention, study design, and procedures (including recruitment rate, adherence, and dropout). Outcome measures include balance, function, falls, strength, fear of falling, health-related quality of life, resource use, and adherence, measured at baseline, three-month, and six-month post-randomization. Blinded assessors collected the outcome measures. Results: Twenty four patients were randomized to control group and 26 to intervention group, with a mean age of 77.6 (range 62–92) years. We recruited 37.5% of eligible participants across the five clinical sites. 77% in the intervention group completed their full exercise programme (including the use of the app). Response rates for outcome measures at 6 months were 77–80% across outcome measures, but this was affected by the COVID-19 pandemic. There was a mean 2.6 ± 1.9 point difference between groups in change in Berg balance score from baseline to 3 months and mean 4.4 ± 2.7 point difference from baseline to 6 months in favour of the intervention group. Less falls (1.8 ± 2.8 vs. 9.1 ± 32.6) and less injurious falls (0.1 ± 0.5 vs. 0.4 ± 0.6) in the intervention group and higher adherence scores at three (17.7 ± 6.8 vs. 13.1 ± 6.5) and 6 months (15.2 ± 7.8 vs. 14.9 ± 6.1). There were no related adverse events. Health professionals and patients had few technical issues with the apps. Conclusions: The motivational apps and trial procedures were feasible for health professionals and patients. There are positive indications from outcome measures in the feasibility trial, and key criteria for progression to full trial were met.
Stuttering Severity Judgments by Speech-Language Pathologists of Bilingual Children Who Do and Do Not Stutter
Authors: Saad Merouwe Selma , Bertram Raymond , Richa Sami , Eggers Kurt
Published: December 2022

Introduction: Recent studies conducted with bilingual populations have shown that bilingual children who do not stutter (CWNS) are often less fluent than their monolingual counterparts, which seems to affect the accuracy with which speech-language pathologists (SLPs) identify stuttering in bilinguals. That is, misdiagnosis appears frequently in bilingual children and is more likely to occur with bilingual CWNS (false positives) than with bilingual CWS (false negatives). Methods: The goal of the current study was to gain insight in the extent of this misdiagnosis. Speech samples of 6 Lebanese bilingual CWNS and 2 CWS were rated by Lebanese SLPs in an audio-only and audiovisual presentation mode. SLPs had to identify each child as stuttering or not and subsequently rate on a 6-point scale the stuttering severity for each child. SLPs also provided background information by means of a questionnaire. Results: The results showed that stuttering severity ratings (1) were on average significantly higher for CWS than for CWNS, (2) were for each CWS higher than for all but one of the CWNS, (3) varied significantly among the CWNS but not the CWS, (4) were not affected by the presentation mode, and (5) correlated positively with the percentage of stuttering-like disfluencies (SLD) and the mean number of iterations, but not with the percentage of other disfluencies (OD). Conclusion: Misdiagnosed bilingual CWNS are perceived by the SLPs as having a mild stutter, primarily based on the frequency of their disfluencies, but can be occasionally rated at par with CWS. Further research differentiating the disfluent speech of bilingual children who do and do not stutter is needed to reach a more adequate diagnosis of stuttering.
Leading Bank Performances under Exntended Caretaker Goverment- Empirical Approach from Thailand
Authors: Debkumar Chatterji Sudip
Published: December 2022

Thailand’s economic performance has historically been determined by the frequency and severity of political de-stability by government collapses mostly organized through army coups. This study investigated the theoretical and empirical literature political uncertainty and economic slowdown arising out of the last coup and caretaker government enforcing the emergency decree to maintain peace and order and the caretaker government being in power until the general elections were held in 2019. This paper scrutinizes the impact of political instability, macroeconomic and bank-specific factors on the performance of leading Thai banks in the context of Thailand. The study selected only two out of top 4 private banks due to the availability of data for the uncertainty period ranging from 2014 to 2018 until elections were held a year later. The study used 8 common measures of bank performance and profitability along with descriptive analyses. Using happiness index as qualitative standpoint and also comparing financial variables with rating agencies prediction, various reports including the Bank of Thailand, the study also presents some new results and a robustness analysis. Our study concludes that political uncertainty was a significant contributor for erratic bank performance.
Understanding the Economics of Solar Powered Irrigation System in Bangladesh
Authors: Akter Taslima , Bari Kazi Ehsanul
Published: December 2022

Solar pump is a more environmental-friendly irrigation option for farmers in Bangladesh. Researchers have found that using solar pump for irrigation is more cost effective. Researchers have found that using solar pump for irrigation is more cost effective as well as less damaging for the environment. Moreover, this relies on renewable energy sources that make it more efficient. Against this backdrop, the objectives of the present study were to understand the profitability analysis of using solar pumps instead of the diesel-run pumps for irrigation and also to identify its determinants. The study collected primary data from four upazilas of Jhenaidah district, purposively selected as the study site. Data were collected from the respondents whose families are involved in agricultural activities. For the analysis of collected data, the study used cost-benefit analysis, while a logit regression analysis was also done for understanding the determinants of using solar energy for irrigation. It is found that the benefit-cost ratio for using solar pump for irrigation by the farmers is 0.277, which implies that the cost is more than the benefit if the households adopt solar pump instead of diesel pumps. On the other hand, the Logit regression analysis found that bigger household size, nearby water sources for irrigation, perceptions on improved production and higher current year yield significantly influence the usage of solar pumps for irrigation. On the contrary, if households were entitled to share irrigation facilities, they are less likely to use solar pumps for irrigation.
Technological Leadership of School Heads and Teachers’ Technology Integration: Basis for the Development of a Training Program
Authors: Maala Elenette B , Lagos Fidelito D.
Published: December 2022

Covid-19 pandemic saw the transition to online distance learning of the education in the Philippines.  This became a challenge to both the teachers and heads of the educational institutions in terms of adapting and utilizing technology for better delivery and effective learning of students.   The study aimed to determine the level of technological leadership of school heads.  Using surveys and tests of collected data, it was revealed that the level of technological leadership of school heads based on technology innovation, technology assessment, technology forecasting, technology management and technology transfer shows a high overall weighted mean. These results showed that the technological leadership of school heads met the quality requirement of becoming technology leaders. Comparing this on teachers’ technology integration using z and t- test, the study also showed that both groups have similar insights regarding the level of technological leadership. The results and conclusions served as basis for developing a training program necessary to further address the needs of school heads and teachers.
Flipaclip Animation Media for Improving Speaking Skills of Elementary School Students
Authors: Sidabutar Yanti Arasi , Hutagalung Insenalia Sampe Roli
Published: December 2022

This study was structured with the aim of improving the speaking skills of fourth grade students of SD Negeri 091537 Hutabayuraja by using flipaclip animation media based on local wisdom. This type of research is Classroom Action Research (CAR), where the teacher is the implementer of learning while the researcher is the observer. The design of this study uses the Kemmis and Mc. Taggart. This research was conducted in the odd semester of the 2021/2022 academic year, namely in July. The subjects of this study were fourth grade students of SD Negeri 091537 Hutabayuraja which consisted of 20 students. The object of research is students' speaking skills. Data collection techniques using tests and observations. Data were analyzed descriptively and presented in tabular form. The results showed an increase in students' speaking skills, the average value of speaking skills in the first cycle of the first meeting was 65.45 and the second meeting was 68.05. In the second cycle, the average value of speaking skills for the first meeting was 70.65 and the second meeting was 89.5. This means that improving learning outcomes by using flipaclip animation media based on local wisdom can improve the speaking skills of fourth grade elementary school students.
Communicative Language Teaching in Selected Students: Basis for Pro-posed Use of Task Based Learning Approach in Developing Speaking Skills
Authors: Maming Jimmy Bernabe , Llena Annalyn Cristobal , Maravilla Wes Harven G.
Published: December 2022

This study employed communicative language education to assist a subset of a public school in Tondo, Manila, Philippines, especially the Junior High School Grade 7 students, in improving their English-speaking abilities. The researchers used the Direct Teaching Method to conduct a teaching and learning process (Pre-test). The students were then given a speaking test. Following the pre-test, the researchers started the teaching-learning process by teaching Communicative Language. After two months of using the communicative language education strategy, the researcher repeated the speaking test (post-test). Compiling the data and calculating the speaking test scores. The following statistical instruments were applied to the data collected for analysis and interpretation: t-Test: Two-Sample Assuming Equal Variances, Weighted Mean, Frequency and Percent Distribution, Standard Deviation, One-Way ANOVA [Single Factor], and the findings of the pre-test and post-test show a considerable improvement in the selected students' speaking ability. Task-based learning is excellent for cultivating language ability because it allows students to participate in natural conversation. The task-based approach gives learners a natural setting in which to utilize language. There are several opportunities for interaction while students try to finish an assignment. Such engagement is said to help with language development since it forces students to converse with one another and articulate their meaning.
Gamification in a Virtual Ecology (GIVE): Enhancing Classroom Engagement in Physical Education among Senior High School Students
Authors: Marcaida John Louise M. , Ortega Hans Christian A. , Castañeda Edzel S. , Cadeliña Pamela Mae M. , Garcia Rolan Randolf I. , Valenzuela Luwy R. , Tolentino Julius Ceazar
Published: December 2022

The study was geared toward determining the influence of integrating Gamification in a Virtual Ecology (GIVE) in enhancing classroom engagement in physical education among senior high school students in a state university in Pampanga, Philippines. This qualitative-descriptive study included a complete enumeration of the Grade 12 Technical-Vocational-Livelihood (TVL) students who voluntarily participated in this qualitative investigation (n = 58) by responding to open-ended questions. Results of the open-ended questionnaire decipher the influence of gamification on students’ level of engagement and the barriers encountered upon its inclusion. The study utilized Braun and Clarke's Thematic Analysis strategy, which was aided by computer-assisted qualitative analysis software, MAXQDA Analytics Pro 2022. The study revealed two emerging themes that described the influence of gamification in the students' virtual ecology, namely: (1) the effects of the integration of gamified instruction on students’ engagement; and (2) students' problems in using gamified instruction. The findings of this study may predate the institutionalization of the prospective enhancement of the teacher’s capabilities through the aid of gamification to improve the classroom engagement of the students in a virtual ecology towards a better understanding of the lessons in physical education settings.
RETRACTION NOTICE TO “Analysis of the Bachelor of Physical Education (BPEd) Program Prospectus through Course Content Assessment”
Authors: Lobo Joseph , Bernardo Bryan Dale
Published: December 2022

This article entitled “Analysis of the Bachelor of Physical Education (BPEd) Program Prospectus through Course Content Assessment” (2022), authored by Joseph Lobo and Bryan Dale Bernardo, published in Vol. 3, No. 11 of International Journal of Multidisciplinary: Applied Business and Education Research. 3(11), 2303 – 2315 has been retracted as requested by the authors.
Surviving Vulnerabilities of Isolation among Widowed Empty Nesters
Authors: Ablanque Argonne Robert A. , Singson Deborah Natalia E.
Published: December 2022

A sufficient number of empty nesters living in isolation had been increasing in population, thus it is encouraged to provide a plethora of research data and studies on gerontology and isolation that could contribute to their wellbeing. This study utilized the descriptive phenomenological analysis and purposive sampling method to determine the five participants.  Inclusion criteria were established to narrow down participants with common conditions. Data were gathered through online interviews and analyzed using Lichtman’s 3 C’s comprised of codes, categories, and concepts. The following themes emerged: economic vulnerability, physical vulnerability, social vulnerability, emotional vulnerability, coping with isolation vulnerabilities, and hopeful aspirations. In conclusion, empty nesters may experience multiple challenges that made them vulnerable in many aspects, but they were also able to develop coping strategies to manage these vulnerabilities. The limitations encountered in this study may be improved by exploring the experiences of empty nesters from other socio-economic categories and conducting a mixed-method study that would generate a broad range of data. The result of the study exposes various vulnerabilities that contribute to challenges encountered by empty nesters. Since the results are limited from generalizing the entire senior citizen population, it could be noted that the resiliency to survive challenging situations promote a holistic approach for aging and positive psychology as results provided varied sources for coping which ranges from both the internal and external sources. Survival elements of connectedness and transcending difficult situations affirm the practicality of promoting life meaning especially during difficult situations.
Frederico Morais, a Semana de 22, o Núcleo Bernardelli e o desejo de revisão histórica do modernismo no Brasil
Authors: Oliva Fernando
Published: December 2022

Este artigo analisa as transformações na produção do crítico brasileiro Frederico Morais (Belo Horizonte, 1936) a partir do início da década de 1980, quando suas posições sobre quais rumos deveria tomar a arte brasileira tornam-se gradativamente menos incisivas, e o tom de seus textos, mais conciliatório. Um discurso mais palatável, em comparação com os combativos anos 1960 e 1970, quando advogava em favor de uma arte de vanguarda no país. Isso acontece simultaneamente à dinâmica de sua incorporação pelo sistema brasileiro de arte, ou seja, uma institucionalização do crítico, que passa a atuar junto às galerias Acervo e Banerj, além de escrever e editar livros e catálogos para companhiascomo Sul América, Banco Sudameris, leilões Soraia Cals e Instituto Itaú Cultural. Nestas publicações, Morais passa a promover uma revisão sistemática da Semana de 22, em favor de um modernismo que, segundo ele, teria se consolidado a partir do Núcleo Bernardelli, no Rio de Janeiro.
A representação simbólica do burnout na revista Exame : o uso ideológico de conteúdos do imaginário
Authors: Contrera Malena Segura , Souza Rafael Rodrigues de
Published: December 2022

Este artigo traz uma análise da reportagem sobre a síndrome de burnout publicada pela revista Exame, edição 1203, de fevereiro de 2020. Problematiza acerca das escolhas editoriais da matéria sobre o tema, assim como procura entender os alinhamentos ideológicos desta categoria de mídia, analisando seu conteúdo em perspectiva simbólica a partir das teorias do imaginário, conforme Malena Contrera e James Hillman, e com o apoio de autores da área da Sociologia do Trabalho, como Richard Sennett e Dietmar Kamper.
Aproximación Conceptual de las Capacidades Comunicacionales en las Organizaciones para la Agenda Global 2030
Authors: Durán Bravo Patricia , Cisneros Martínez Nancy G.
Published: December 2022

La Agenda Global 2030 convoca a las organizaciones para ser líderes de la transformación social, para ello, se requieren sistemas comunicacionales capaces de interpretar, crear y coordinar recursos simbólicos para contribuir al bienestar colectivo. A partir de la nueva teoría estratégica, la comunicología y la diversidad cognitiva se presenta una aproximación conceptual de las capacidades del sistema comunicacional de la organización que active procesos de colaboración para el desarrollo sostenible.
Estratégias comunicativas nos processos de parcerias para implementação da Agenda 2030 da ONU
Authors: Kunsch Margarida M. Krohling
Published: December 2022

Este artigo trata de uma temática mundial na atualidade: a Agenda 2030 da Organização das Nações Unidas (ONU) e os  17 Objetivos de Desenvolvimento Sustentável (ODS), com foco no último – Fortalecer os mecanismos de implementação e revitalizar a parceria global para o desenvolvimento sustentável e o papel da comunicação neste contexto. Situar o papel estratégico da comunicação na promoção da sustentabilidade, mediante um trabalho integrado entre os atores e o poder público, a sociedade civil e as organizações, constitui o propósito básico deste texto reflexivo.
Organizações, discursos e práticas em sustentabilidade: um estudo da comunicação ESG em relatórios corporativos
Authors: Lobato José Augusto Mendes , Neiva Rodrigo Cesar Severino
Published: December 2022

Este trabalho tem como objetivo promover uma análise crítica sobre a abordagem de tópicos de sustentabilidade em relatórios produzidos por organizações atuantes no Brasil. Para isso, promovemos uma análise de conteúdo qualitativa, ancorada na estrutura editorial e seus elementos em nove relatórios de desempenho, seguida da análise discursiva de capítulos em que essa abordagem se evidencia. Identificamos que a descrição de compromissos e temas materiais é frequentemente associada ao modelo de gestão das organizações, buscando atender agendas globais segundo as atividades e estratégias de negócios.
O orientalismo de Mary Wollstonecraft sob a ótica de Nawal el Saadawi: um diálogo intercultural
Authors: Bonfim Sarah , Luz Flávia Abud
Published: December 2022

Há uma contradição a qual impede que a leitura de Reivindicação dos direitos da mulher (1792), de Mary Wollstonecraft, flua como um projeto de liberdade: as posições dela com relação aos turcos mulçumanos, em especial às mulheres desse grupo. Neste artigo, nossa proposta é apresentar uma contribuição a esse debate, partindo de excertos do livro que tangenciam dois pontos considerados fundamentais em nossa análise: a questão cultural do harém e a questão religiosa sobre a negação de uma alma imortal às mulheres muçulmanas. Para isso, recorremos à obra de Nawal El-Saadawi tendo em vista duas importantes perspectivas, a saber, o conceito de outridade de Grada Kilomba e a concepção de diálogo intercultural de Abdullah An-Na’im. Nesse sentido, nosso objetivo é contribuir para a reflexão sobre os preconceitos reiterados na obra de Wollstonecraft. Buscamos discutir esses aspectos sem que sejam desconsideradas outras contribuições da filósofa para a história da filosofia política.
Taxonomy and faunistics of the genus Scrobipalpa Janse, 1951 (Lepidoptera, Gelechiidae) in southern Siberia
Authors: BIDZILYA OLEKSIY , HUEMER PETER , ŠUMPICH JAN
Published: December 2022

Thirteen new species of Scrobipalpa Janse, 1951 are described: S. nupponeni sp. nov. (Russia: Buryatia, Altai), S. rutjani sp. nov. (Kyrgyzstan; Russia: Novosibirsk reg., Tuva), S. tannuolella sp. nov. (Russia: Tuva), S. kullbergi sp. nov. (Russia: Tuva), S. lobata sp. nov. (Russia: southern Ural, Altai, Tuva, Buryatia), S. inexplictata sp. nov. (Russia: Altai; Armenia), S. altubura sp. nov. (Russia: Altai, Tuva, Buryatia), S. krasnogorka sp. nov. (Russia: Altai), S. buryatica sp. nov. (Russia: Buryatia), S. albiflava sp. nov. (Russia: Altai, Tuva), S. ravida sp. nov. (Russia: Buryatia, Zabaikalskiy krai), S. ochronerva sp. nov. (Russia: Buryatia) and S. ochraeata sp. nov. (Russia: Zabaikalskiy krai). Four new generic combinations are proposed: Scrobipalpa saxatilis (Povolný, 1996) comb. nov.; Scrobipalpa truncata (Povolný, 2002) comb. nov.; Scrobipalpa superba (Povolný, 1996) comb. nov. and Scrobipalpa cinerea (Povolný, 1996) comb. nov. Five new synonyms are established: S. punctata (Povolný, 1996) syn. nov. of S. zaitzevi Piskunov, 1990; S. abstrusa Huemer & Karsholt, 2010 syn. nov. of S. truncata (Povolný, 2002); S. pinosa (Povolný, 2001) syn. nov. of S. ferruginosa (Povolný, 2001); S. kyrana (Povolný, 2001) syn. nov. of S. similis Povolný, 1973 and S. zouhari Povolný, 1984 syn. nov. of S. rebeli (Preissecker, 1915). Scrobipalpa sibirica Bidzilya, 2009 sp. rev., stat. nov. is taken out from synonymy with S. occulta (Povolný, 2002) and S. japonica Povolný, 1977 sp. rev., stat. nov. is taken out from synonymy with S. rebeli (Preissecker, 1914). Six species are recorded from Russia for the first time: Scrobipalpa superstes Povolný, 1977; S. punctulata Li & Bidzilya, 2019; S. strictella Bidzilya & Li, 2010; S. inferna Povolný, 1973; S. mongolica Povolný, 1969 and S. mixta Huemer & Karsholt, 2010. Scrobipalpa notata (Povolný, 2001) is new for Armenia, S. frugifera Povolný, 1969 and S. mixta are new for Kazakhstan, S. acuta (Povolný, 2001) and S. ferruginosa are new for Mongolia, S. tenebrata (Povolný, 2001) is new for China, S. zaitzevi is new for Tajikistan and Afghanistan, S. truncata is new for Kyrgyzstan and Mongolia, S. marmorella Povolný, 1969 and S. candicans (Povolný, 1996) are new for Tajikistan. The male genitalia of S. ferruginosa, and the female genitalia of S. bidzilyai (Povolný, 2001), S. chitensis (Povolný, 2001), S. tenebrata, S. cinerosella Bidzilya, 2009 and S. japonica are described for the first time. Improved diagnosis and additions to descriptions are provided for some little known and poorly diagnosed species. Adults and genitalia are illustrated for all new species and for most of the species which represent new faunistic records.
1. A Secret Inheritance
Authors: Evans Dorinda
Published: December 2022

Chapter one gives an overall view of William Rimmer's life, how he was perceived, and the impact of family mental illness on his life and reputation. Not only was Rimmer a bipolar artist but also his father mistakenly claimed to be the heir to the French throne, the missing Dauphin. Rimmer tried to make a living as a printmaker, a painter, and a sculptor. He also became a physician and an instructor in art anatomy. This last occupation provided his chief source of income. Self-taught and a Bostonian, he strayed outside of New England only to teach in New York at the Cooper Union School of Design for Women of which he became director. Although he achieved fame internationally as a sculptor and author of two books on art anatomy, he exhibited rarely and created most of his artwork for family and friends.
2. The Two-Dimensional Portraits in Context
Authors: Evans Dorinda
Published: December 2022

Chapter two considers all Rimmer’s known portraits, which included two of his wife, and dated from 1841 to the early 1860s. He tended to experiment and appears to have been especially interested in effects of light and shadow that are suggestive of an immaterial identity. Indeed, he incorporated an identifiable musical score in his portrait of Eliza Kent as a means of conveying a sense of her non-physical self. As a trained physician, he included a frank acknowledgment of illness such as depression or deformity in some of his pictures. He lived through the Civil War, and his quick sketch from life or memory of an African American soldier, joining Abolitionist Robert Shaw in the famous march of the 54th Regiment from Boston, is related to allegorical war pictures. In other work, including sculpture, it is possible to see the effect of his bipolar illness.
4. Swedenborg and Enigmatic Pictures
Authors: Evans Dorinda
Published: December 2022

Rimmer was a non-denominational Christian who typically did not attend church, but, rather, he developed his own religious ideas. These included an acceptance of Emanuel Swedenborg's anti-Catholicism and a belief in much of Swedenborg's accounts of visits to celestial spheres. A number of Rimmer's works of art, such as Victory and Interior: Before the Picture, are explored here for the first time within the context of Swedenborg's writings. As an independently minded artist, he benefited from his own theological exploration. As his paintings of Horses at a Fountain and The Gamblers, Plunderers of Castile (or his drawing of Job's despair with a prominent role given to Elihu) showed, he went beyond the Bible to use relatively esoteric sources. Frequently there is a complex moral message in his work that is not immediately apparent but always depends upon visual clues.
140 Years of Global Ocean Wind-Wave Climate Derived from CMIP6 ACCESS-CM2 and EC-Earth3 GCMs: Global Trends, Regional Changes, and Future Projections
Authors: Meucci Alberto , Young Ian R. , Hemer Mark , Trenham Claire , Watterson Ian G.
Published: December 2022

We present four 140-yr wind-wave climate simulations (1961–2100) forced with surface wind speed and sea ice concentration from two CMIP6 GCMs under two different climate scenarios: SSP1–2.6 and SSP5–8.5. A global three-grid system is implemented in WAVEWATCH III to simulate the wave–ice interactions in the Arctic and Antarctic regions. The models perform well in comparison with global satellite altimeter and in situ buoys climatology. The comparison with traditional trend analyses demonstrates the present GCM-forced wave models’ ability to reproduce the main historical climate signals. The long-term datasets allow a comprehensive description of the twentieth- and twenty-first-century wave climate and yield statistically robust trends. Analysis of the latest IPCC ocean climatic regions highlights four regions where changes in wave climate are projected to be most significant: the Arctic, the North Pacific, the North Atlantic, and the Southern Ocean. The main driver of offshore wave climate change is the wind, except for the Arctic where the significant sea ice retreat causes a sharp increase in the projected wave heights. Distinct changes in the wave period and the wave direction are found in the Southern Hemisphere, where the poleward shift of the Southern Ocean westerlies causes an increase in the wave period of up to 5% and a counterclockwise change in wave direction of up to 5°. The new CMIP6 forced wave models improve in performance compared to previous CMIP5 forced wave models, and will ultimately contribute to a new CMIP6 wind-wave climate model ensemble, crucial for coastal adaptation strategies and the design of future marine offshore structures and operations.

Significance Statement

The purpose of this study is to advance the understanding of ocean wind-wave climate evolution over the twentieth and twenty-first centuries and to effectively communicate the long-term impacts of climate change in diverse wind-wave climatic regions across the globe. The 140-yr continuous model results produced in this work are crucial to studying changes in extreme sea states and investigating the relationship between interdecadal periodic oscillations and long-term climate trends. The dataset produced can be used to gain further insight into the substantial long-term changes of the polar wind-wave climate caused by the rapid decrease of sea ice coverage, and the evolution of the directional changes in the sea states triggered by climate change.
The Stratosphere–Troposphere Oscillation as the Dominant Intraseasonal Coupling Mode between the Stratosphere and Troposphere
Authors: Shen Xiaocen , Wang Lin , Scaife Adam A. , Hardiman Steven C. , Xu Peiqiang
Published: December 2022

Changes in the stratospheric polar vortex (SPV) can remarkably impact tropospheric circulation. Based on the diagnosis of reanalysis data, this study finds that the location shift rather than the strength change dominates the intraseasonal variability of SPV. Further analysis suggests that it couples well with the tropospheric circulation, forming an intraseasonal stratosphere–troposphere oscillation (STO). The STO shows periodic westward propagation throughout its life cycle and has a deep structure extending from the troposphere to the stratosphere. It reflects the movement of the SPV toward North America, then the North Pacific, Eurasia, and the North Atlantic, and causes significant changes in surface air temperature over North America and East Asia. The mechanism of the STO involves Rossby wave propagation between the troposphere and stratosphere and cross-scale interactions in the troposphere. Upward Rossby wave propagation from the troposphere over East Asia maintains the STO’s stratospheric component, and the reflection of these waves back to the troposphere contributes substantially to the STO’s tropospheric center over North America. Meanwhile, the linear and nonlinear processes explain the STO’s westward propagation in the troposphere, which facilities vertical wave propagation changes. The STO unifies the SPV shifts, the retrograding tropospheric disturbances, and the wave coupling processes into one framework and provides a holistic view for a better understanding of the intraseasonal stratosphere–troposphere coupling. Given its oscillating nature, time scale, and widespread surface response, the STO may be a potential source of predictability for the subseasonal-to-seasonal prediction.

Significance Statement

Stratospheric circulation plays a vital role in influencing tropospheric weather and climate, but its variability and coupling with the troposphere have not been fully understood for the intraseasonal time scale. This study finds that the Northern Annular Mode is the leading mode of variability in the extratropical Northern Hemisphere stratosphere on time scales longer than 60 days, which reflects the changes in the intensity of the stratospheric polar vortex. In contrast, the shift of the stratospheric polar vortex excels as the leading mode on time scales shorter than 60 days and is identified as a stratosphere–troposphere oscillation (STO) phenomenon. In the stratosphere, the STO is characterized by the shift of the polar vortex and rotates clockwise with time. In the troposphere, the STO is manifested as a large-scale westward-propagating circulation in the midlatitudes, with significant near-surface temperature anomalies across the continents. The formation of the STO is further attributed to the vertical and horizontal Rossby wave propagation. As STO is a periodic oscillation, it may serve as a potential predictability source for subseasonal-to-seasonal climate prediction.
Understanding and Reducing Warm and Dry Summer Biases in the Central United States: Improving Cumulus Parameterization
Authors: Sun Chao , Liang Xin-Zhong
Published: December 2022

Most climate models still suffer large warm and dry summer biases in the central United States (CUS). As a solution, we improved cumulus parameterization to represent 1) the lifting effect of small-scale rising motions associated with Great Plains low-level jets and midtropospheric perturbations by defining the cloud base at the level of condensation, 2) the constraint of the cumulus entrainment rate depending on the boundary layer depth, and 3) the temperature-dependent cloud-to-rainwater conversion rate. These improvements acted to (i) trigger mesoscale convective systems in unfavorable environmental conditions to enhance total rainfall amount, (ii) lower cloud base and increase cloud depth to increase low-level clouds and reduce surface shortwave radiation, (iii) suppress penetrative cumuli from shallow boundary layers to remedy the overestimation of precipitation frequency, and (iv) increase water detrainment to form sufficient cirrus clouds and balanced outgoing longwave radiation. Much of these effects were nonlocal and nonlinear, where more frequent but weaker convective rainfall led to stronger (and sometimes more frequent) large-scale precipitation remotely. Together, they produced consistently heavier precipitation and colder temperature with a realistic atmospheric energy balance, essentially eliminating the CUS warm and dry biases through robust physical mechanisms.
Diffuse Reflectance Spectroscopy and Principal Component Analysis to Retrospectively Determine Production History of Plutonium Dioxide
Authors: Villa-Aleman Eliel , Christian Jonathan H. , Darvin Jason R. , Foley Bryan J. , Dick Don D. , Fallin Brent , Fessler Kimberly A. S.
Published: December 2022

Diffuse reflectance spectroscopy measurements in the shortwave infrared (930–1600 nm) spectral region were acquired for Pu2(C2O4)3•9H2O and its thermal decomposition product, PuO2. We analyzed a total of eight PuO2 samples that were produced at different calcination temperatures (300, 350, 450, 525, 600, 675, 750, and 900 °C). Our goal was to identify spectroscopic fingerprints that could be used to gain retrospective information regarding the production parameters of these important nuclear compounds. The diffuse reflectance spectrum of Pu2(C2O4)3•9H2O features several broad bands that currently preclude detailed analysis. However, all PuO2 samples produced relatively sharp spectral features that got sharper and more intense for samples that were produced at higher calcination temperatures. The electronic band observed at 1433 nm in the diffuse reflectance spectra of PuO2 was found to be a sensitive indicator of crystallinity; a result that is corroborated by ancillary Raman spectroscopy measurements. Principal component analysis of diffuse reflectance spectra was able to clearly rank and categorize PuO2 samples based on the calcination temperature that was employed during their production. Thus, we show herein that important retrospective information pertaining to the process history of PuO2 can be gained through the relatively simplistic combination of diffuse reflectance spectroscopy and principal component analysis. This discovery presents a new method for determining the provenance and process history of PuO2 and should have an impact in the fields of nuclear forensics and nuclear nonproliferation.
Physician Self-Reported Practice Patterns: Midazolam for Minor Procedures in Pediatric Patients
Authors: Trotter Zola , Mecham Cherisse , Bhattarai Bikash
Published: December 2022

Midazolam is frequently used as a single agent to provide minimal sedation (also called anxiolysis) when performing procedures in minor children. Published guidelines on the optimal use of intranasal (INM) and oral midazolam (POM) are lacking. The purpose of this study is to explore the self-reported physician practice related to midazolam use in facilitating minor procedures in children. We developed a survey that was approved by the Academy of Pediatrics Section on Emergency Medicine (APP-SOEM) and was then electronically distributed via its listserve. Questions were posed about the therapeutic and maximum dosing of INM and POM, consideration of Nothing-By-Mouth (NPO) status, use of cardiopulmonary monitors, as well as discharge criteria. There was a 47% (218/465) response rate. For therapeutic INM doses, 65% of responders used a dose range of 0.3 to 0.6 mg/kg, and 75% selected a maximum dose of 10 mg irrespective of the child’s weight. About 20% of the responders selected a dosage range of 0.7 to 1 mg/kg for therapeutic POM dose, with 43% opting for a maximum dose of 20 mg irrespective of the child’s weight. We observed a dichotomous variation in reported physician use of cardiopulmonary monitors; 42% never employ monitors, and the remainder used monitors some of the time. There was consensus on the NPO status and discharge criteria; 80% of physicians did not consider NPO status prior to midazolam use. The level of alertness was the most commonly selected discharge criterion. This nationwide survey of physicians indicates practice variation with midazolam dosing and cardiopulmonary monitor usage when performing minor procedures in children. Implementing practice guidelines, specifically for minimal sedation with mainstay agents such as midazolam, may standardize physician practice and improve overall patient care.
Social work field education in the United Arab Emirates: Emerging standards, opportunities, and challenges
Authors: Mitchell Vivienne , Tedam Prospera , Wagner Beverly , Abu-Sarhan Taghreed
Published: December 2022

This article describes the current status of social work field education in the United Arab Emirates. Using a case study approach, the authors explore field education differences and commonalities between two federal higher education institutions. Although nascent, United Arab Emirate professional organizations have been established or are in the process of being established. The authors call for further development of field guidelines and standards of practice, weighing the potential costs and benefits of such standards. Practical recommendations for field education in countries where social work is an emerging discipline are also provided.
Realism, reckless states, and natural selection
Authors: Rendall Matthew
Published: December 2022

Why is daredevil aggression like Russia’s war on Ukraine such an important factor in world politics? Neither offensive nor defensive realists give a fully satisfactory answer. This paper maintains that the problem lies in their shared assumption that states pursue security. Tracing neorealism’s roots in evolutionary economics, and hence indirectly in biological theories of natural selection, I argue that many policies are compatible with state survival. What is hard is surviving as a great power. States that rise to that rank, and remain there, behave as if they sought to maximize their influence, not their security. This Darwinian competition selects in favor of states with expansionist institutions and ideologies. Failing to recognize this phenomenon risks conferring a spurious legitimacy on imperialism. At the same time, neorealists have also committed a fallacy familiar to biologists: assuming that traits enhancing group fitness are selected even when they diminish fitness in intragroup competition. Whereas interstate competition selects in great powers for traits that promote influence-maximization, with the spread of democracy, intrastate competition increasingly selects for security-seeking. Yet the former process sometimes still dominates the latter, above all in authoritarian great powers.