bluuebunny/crossref_metadata_2025 huggingface dataset:
Technology of protection of authentication data of computer network users
Authors: Khlaponin Yuri , Vyshnyakov Volodymyr , Komarnytskyi Oleg
Published: March 2024

The article is devoted to the problem of perfect protection of authentication data of users of computer systems, especially in the case of a large number of different rights and powers that are personally granted to users. The importance of this problem increases especially when the number of such users in the system is hundreds or thousands. At the same time, each of them must create conditions for access only to their data and ensure protection against any outside interference, both by other users and by staff. A typical example of such conditions are secret electronic voting systems. The software and technical solutions described in this work have passed many years of testing and continue to be practically used in the electronic voting system of the Kyiv National University of Civil Engineering and Architecture. This system is regularly used for conducting elections to student self-government bodies and for surveys among students regarding the quality of teaching subjects. With the help of this system, elections of leaders of the Red Cross Society of Ukraine were held during the pandemic, which was associated with the Covid-19 virus. The mathematical basis of the described authentication data protection technology is the theory of algebraic groups, namely, the problem of discrete logarithmization over large Galois fields. Thanks to the use of cryptographic transformations over these fields, instead of known hash functions, it was possible to get rid of the possibility of collisions and neutralize the disclosure of passwords by attackers who were able to do it with the help of specialized Internet resources. It was also possible to increase resistance to brute-force password cracking, since conversions to Galois fields take ten times more time than hash function calculations.
Mindful Mechanisms: Drawing Parallels Between the Quantum Domain and the Three Bodies (Trikaya) of Buddhist Ontology
Authors: Leong David
Published: March 2024

This study illuminates the intriguing parallels between Buddhism, consciousness, and the principles of quantum physics. It engages in a nuanced exploration of the Buddhist concept of _pratītya-samutpāda_, or ‘dependent origination,’ and its resonance with quantum theory's elucidation of the interconnectedness and non-locality in the universe. The paper presents a cross-disciplinary dialogue, bridging the spiritual wisdom of Buddhism with quantum theory's frontier understanding of reality through observation and consciousness at the _Trikaya_ realms, and discusses consciousness’s place within this nexus. By doing so, the study endeavours to enhance our comprehension of the subjective ‘self’ in relation to the temporality of the objective ‘reality’ as portrayed in both spiritual and scientific discourses. This intersectionality offers new insights and perspectives on the nature of consciousness and reality, potentially stimulating further research in physics and philosophy.
New times, new systems for learning surger
Authors: Rodríguez Montes J.A.
Published: March 2024

The evolution from the traditional surgical tékhne to the current technological surgery is analyzed and the problems raised in this transition are specified. The educational methodology in surgery, the origin of the current surgical training programs of excellence, the problems that arise for learning new technologies, as well as the learning modalities based on simulation and virtual reality are presented. It is concluded that of all available methods, simulation is the current valid way of learning and that it is necessary to establish universal simulation programs in surgical training plans.
Gordon Matta-Clark’ın Eserlerinde Evin Yıkımı ve Modernizm Eleştirisi
Authors: Durak Fide Lale , Emmungil Karamanoğlu Serap
Published: March 2024

Bu çalışmada, özellikle 60’lı ve 70’li yıllarda ortaya çıkan modernizme karşı gelişen tartışmaların felsefi kaynakları ve sanatçı Gordon Matta-Clark’ın, mimari yapıları kullanarak ürettiği sanat eserlerindeki ev imgesi araştırılmıştır. Antik Yunan’dan modernizme kadar felsefenin konusu olagelen varoluş kavramı, Locke, Hume, Descartes, Kant, Heidegger gibi düşünürlerin görüşleri ile birlikte ele alınmış; varoluşa getirilen deneysel ve rasyonel yaklaşımların bir parçası olarak mekân, uzay ve zaman kavramlarının tanımlamalarına yer verilmiştir. Modern dönemde mekâna yönelik öznel yaklaşımlara dikkat çekilerek mekânın deneyimlenmesi Matta-Clark’ın eserleri bağlamında incelenmiştir. Eserlere konu olan evin yıkımının somut ve soyut olarak taşıdığı anlamlar, Lefebvre’nin mekânın yeniden üretilmesi yaklaşımıyla ve mekân-ideoloji arasındaki ilişkiyle çözümlenmiştir.
Pengaruh Substitusi Tepung Sagu (Metroxylon sagu R) pada Terigu terhadap Karakteristik Kue Kering
Authors: Rahmawati Aghnia , Putranto Kelik , Tristianne Anne
Published: March 2024

There are so many kinds of foods made of wheat flour. The dependency on wheat flour will be a problem in the future because wheat as raw material could not be cultivated in Indonesia. The Government and private companies have to import wheat from other countries to fulfil people need on wheat flour which rise from year to year. Wheat flour as raw material in food production contain high glycemic value that is not good for our health. One of the alternatives to replace wheat flour is sago flour, because it contains high carbohydrate and other nutrition. The most important thing is that sago flour is gluten free. Sago flour is suitable for cookies making. Research had been done at the Laboratory of Agriculture Faculty UICM and at Chemistry Laboratory of Agriculture Faculty Ma’soem University. The objective of the research was to find out the effect of sago flour substitution to wheat flour on the characteristics of cookies. The experimental method was applied in this research with 8 treatments and repeated 3 times. The treatments were sago substitution of 0%(A), sago substitution of 10%(B), sago substitution of 20% (C), sago substitution of 30%(D), sago substitution of 40% (E), sago substitution of 50% (F), sago substitution of 60% (G), and sago substitution of 70% (H). The organoleptic test was applied on colour, taste, aroma and texture. Result of the research showed that treatment H produced cookies with the best characteristic according to colour and aroma.
HESA Graduate Students’ International Involvements and Civic Engagement
Authors: Slantcheva-Durst Snejana
Published: March 2024

This study maps the types of international involvement opportunities available to HESA: Higher Education and Student Affairs graduate students in the U.S.A., as seen through the eyes of the students, and analyzes the impact of these students’ diverse international involvements on their orientation towards social responsibility. The study follows a survey research design. The study’s results indicate low levels of international exposure amongst HESA graduate students across diverse programs, and moderate rates of orientation towards civic responsibility. HESA students’ orientation towards social responsibility can successfully be predicted by a combination of five variables, three of which represent curricular and co-curricular environmental engagements: listening to an international speaker, discussing the ways the U.S. higher education links to the rest of the world, and attending presentations of study abroad students. The findings aim to inform program directors and faculty on existing opportunities for international exposure, on the rate of student involvements in them, as well on the importance of international exposures for their students’ future professional preparation.
ФУНКЦІОНАЛЬНО-СТИЛІСТИЧНІ ОСОБЛИВОСТІ ЮРИДИЧНОГО, ДІЛОВОГО ТА ПОЛІТИЧНОГО ДИСКУРСІВ
Authors: НАГОРНА Ольга
Published: March 2024

У сучасному світі юридична мова та юридичний дискурс викликають все більший інтерес у дослідників різних галузей науки. Це пов'язано з тим, що юридична мова є складною і багатогранною системою, яка виконує важливі функції в суспільстві. Юридична мова використовується в різних комунікативних ситуаціях, пов'язаних із застосуванням законів та юридичних документів. У таких ситуаціях юридична мова часто не може існувати в чистому вигляді, зберігаючи свою літературну, офіційну форму. Психолінгвісти, когнітивісти та лінгвокультурологи вивчають юридичну мову в різних аспектах. Вони досліджують, як юридична мова впливає на мислення та поведінку людей, як вона формується та розвивається, як вона відображає культурні цінності та норми. Мета статті – проаналізувати функціонально-стилістичні особливості юридичного та політичного дискурсів. Наукова новизна. Вперше доведено, що юридичний дискурс можна уявити як сферу, в центрі якої знаходяться тексти чинних законів, зокрема основних, таких як Конституція, кодекси та закони, прийняті на державному рівні. Ці тексти є основою юридичного дискурсу, вони встановлюють норми поведінки та регулюють суспільні відносини. Вони також є еталоном для виробництва законів та юридичних документів нижчого рівня, таких як регіональні, відомчі та приватні. Висновки. Автор приходить до висновків, що що юридичний дискурс має ядро, яке складається з закону та мови закону. Це ядро є основою юридичного дискурсу, оскільки воно визначає норми поведінки та регулює суспільні відносини. Ядро юридичного дискурсу поступово поширюється на периферійні області, пов'язані з різними соціальними сферами. У цих сферах закон стає об'єктом рефлексії, обговорення та інтерпретації. Це відбувається під впливом багатьох факторів, зокрема емоційних, когнітивних та культурних. У результаті юридичний підстиль взаємодіє з іншими функціональними стилями мови, що призводить до взаємного збагачення стилів та розвитку мови загалом. Англомовний політичний дискурс можна розглядати як спосіб, яким люди спілкуються та взаємодіють один з одним. Він дозволяє нам створювати і обмінюватися знаннями, формувати думки та позиції, а також впливати на інших людей. Англомовний політичний дискурс тісно пов’язаний з юридичним дисекурсом, який мало досліджений у вітчизняній філології.
overview of farms operated by socially disadvantaged, women, and limited resource farmers and ranchers in the United States
Authors: Todd Jessica E. , Whitt Christine , Key Nigel David , Mandalay Okkar ,   United States. Department of Agriculture. Economic Research Service
Published: March 2024

The U.S. Department of Agriculture (USDA) recognizes several groups of farmers who have been historically underserved by USDA and operates several programs and policies targeting these groups. Yet, there is limited information about the current financial health of the farms these producers operate, their credit and agricultural program use, which inhibits the measurement of progress toward more equitable outcomes. This report provides an overview of the financial characteristics of the farms operated by socially disadvantaged (individuals identifying as Black or African American, American Indian or Alaska Native, Hispanic or Latino, and Asian or Pacific Islander), women, and limited resource producers (farms with low sales and low household income), using data from the 2017-20 annual Agricultural Resource Management Survey.
Alemania, en la encrucijada: el cambio de modelo económico
Authors: Buisán Mario
Published: March 2024

El principal objetivo del presente artículo es analizar la evolución de la economía alemana en los últimos años, indagando en particular en el modelo económico que ha sustentado su desempeño económico. Se pretende examinar la pervivencia del mismo en un contexto económico y político que se ha modificado radicalmente en estos años y definir aquellos puntos que, ante la evidencia de la necesidad de transformación del actual modelo, se considera que deben formar parte del nuevo modelo económico. Los pobres resultados que muestra la economía alemana en el periodo considerado nos llevan a valorar si la mala evolución es fruto de dificultades de índole coyuntural o, por el contrario, estamos asistiendo a problemas de tipo estructural que requerirían decisiones políticas y económicas ambiciosas para que vuelva a una senda de crecimiento sostenido. Si bien no existe un claro consenso sobre la naturaleza de las dificultades, sí lo hay sobre la necesidad de que la economía alemana se embarque en un programa que pueda conjugar reformas estructurales con una fuerte inversión, tanto pública como privada.
Principales resultados y conclusiones de la revisión intermedia del Marco Financiero Plurianual UE 2021-2027
Authors: Sánchez Cifuentes Victoria , Carcelén Ordóñez María Victoria
Published: March 2024

El 20 de junio de 2023 la Comisión Europea publicó su propuesta de revisión del Marco Financiero Plurianual (MFP) 2021-2027, integrado por un paquete legislativo que incluye la creación de un Mecanismo para Ucrania, el establecimiento de una Plataforma de Tecnologías Estratégicas para Europa (STEP, por sus siglas en inglés), así como un refuerzo en la política migratoria, en su dimensión interior y exterior de la UE, y la actualización de los costes de  administración de las instituciones comunitarias.
El 1 de febrero el Consejo llegó a un acuerdo político unánime sobre los elementos principales del paquete legislativo.
Los colegisladores llegaron a acuerdos sobre los textos legislativos del paquete en los primeros diez días de febrero.
El 29 de febrero está previsto el acto institucional de firma del acuerdo sobre la revisión por las instituciones y, el 1 de marzo, la publicación en el Diario Oficial de la UE, así como su inmediata entrada en vigor.
El resultado final de la revisión es menos ambicioso que la propuesta inicial de la Comisión. No obstante, proporcionará la financiación necesaria para atender los desafíos más urgentes, en concreto el apoyo financiero a Ucrania y el refuerzo de la política migratoria de la Unión.
Implementasi Kewenangan Penyuluhan Hukum oleh Notaris
Authors: Tenggara Ananda Pradhitya
Published: March 2024

Penelitian ini bertujuan untuk menganalisis konsep sosialisasi undang-undang dalam Undang-Undang Jabatan Notaris dan menganalisis bentuk sosialisasi hukum yang dapat dilakukan oleh Notaris. Tesis ini diharapkan dapat bermanfaat sebagai sumber kajian untuk mengembangkan ilmu hukum secara teoritis dan sebagai pedoman bagi Notaris dalam melaksanakan tugas dan kewajibannya memberikan sosialisasi hukum agar tidak melampaui batas kewenangan secara praktis.  Kewenangan Notaris untuk memberikan sosialisasi hukum kepada pihak-pihak yang berkepentingan dalam pembuatan akta otentik merupakan bentuk pemberian pemahaman hukum terkait dengan perbuatan hukum yang akan dituangkan dalam Akta sesuai dengan ketentuan peraturan perundang-undangan. Kewenangan Notaris dalam memberikan sosialisasi hukum kepada kliennya dapat dibedakan menjadi 2 (dua) bentuk yaitu sosialisasi hukum yang diikuti dengan pembuatan akta dan sosialisasi hukum tanpa diikuti dengan pembuatan akta. Bentuk yang pertama, Notaris harus memberikan penjelasan mengenai keadaan hukum yang sebenarnya sesuai dengan ketentuan peraturan perundang-undangan yang berlaku, untuk menjelaskan hak dan kewajiban para pihak. Bentuk yang kedua adalah kewenangan Notaris terkait dengan kewenangan untuk menolak memberikan sosialisasi hukum kepada para pihak berdasarkan alasan yang sah, dibenarkan oleh peraturan perundang-undangan yang berlaku dan pedoman perilaku Notaris
Los desafíos del jazz en Jalisco
Authors:   Universidad de Guadalajara, Braux Nathalie Lucie
Published: March 2024

En 2001, como consecuencia de la enfermedad y muerte del famoso pianista Carlos de la Torre, salen de la penumbra numerosos músicos de muy alta calidad en conciertos y homenajes. Sorprendida de que tanto talento permanezca oculto, la clarinetista y saxofonista francesa Nathalie Braux se promete contar la historia de estos grandes jazzistas. Un reto mayúsculo: sumergirse en las casi inexploradas aguas del jazz en Jalisco de los setenta y ochenta confrontan a la autora con una gran ignorancia y pobre documentación al respecto. Además de emprender una extensa revisión en la prensa de la época, recuperar programas de mano y pósteres, Braux entrevista a algunos de los más representativos maestros de la escena del jazz y jazz-rock, en encuentros filmados por Jorge Bidault. El resultado es una crónica fundamental para los entusiastas de los ritmos sincopados y para cualquier lector interesado por la cultura musical jalisciense.
Iberoamérica sonora. Músicos en efervescencia
Authors:   Universidad de Guadalajara, Blanc Rojas Enrique , Inzillo Nicolás Adolfo , Pérez Vargas William Humberto , Graziano Martín Emanuel , Gabriel Plaza Héctor , Maira Benavente Manuel José , Padrón Poleo William Enrique , Robles Bayancela Gabriela Andrea , Monsalve Buritica Jaime Andrés , Vega Pinzón Luis Daniel , Garay Acevedo Juan Carlos , Londoño Molina Diego Alejandro , Hidalgo Baca Juan Carlos , Acosta Santos Jaime , Cortés Arce David Anselmo , Ferrer Ben-Amar Pablo , Arcos Landa Adalberto
Published: March 2024

A lo largo de América Latina, España e incluso Estados Unidos existen periodistas musicales, críticos y melómanos que se comprometen a favor de aquella música que merece ser descubierta, compartida, consumida y disfrutada. Todos estos se han agrupado y conformado la Red de Periodistas Musicales de Iberoamérica (Redpem), a partir de donde buscan, en un sentido, equilibrar la oferta musical de los ritmos comerciales con poca originalidad, y en otro sentido, fomentar una visión identitaria que busque preservar y potenciar la voz de nuestras culturas estableciendo un diálogo constante con la música contemporánea global.
Tenun Songket Kampung Wisata Tenun Khatulistiwa Kota Pontianak
Authors: Arkanudin Arkanudin
Published: March 2024

This research aims to describe sogket weaving in equatorial weaving tourism village. The existence of this village began to be widely known after it was inaugurated by the Mayor of Pontianak in 2018. The research method was descriptive qualitative research. Data collection techniques include interviews, observations, and literature searches. The results showed that weavers in this village still produce songket motifs and patterns typical of Pontianak Malay, but Sambas characteristics dominate even though they use gill motif fabrics. The patterns and textures are also innovations of new creations from the craftsmen themselves. The new motif, which is a weaver s creation, does not yet have a name like a typical Pontianak Malay motif or a typical Sambas songket weaving cloth.
piNET: An Automated Proliferation Index Calculator Framework for Ki67 Breast Cancer Images
Authors: Geread Stephny
Published: March 2024

Robust algorithms which are generalizable to multicenter datasets have large potential in digital histopathology. Combatting challenges such as different staining protocols, images, stain and scanner vendors, provide significant value to diagnostic pathology. Automated workflows have the potential to decrease turnaround time, improve efficiency and accuracy. In this work, two different frameworks for proliferation index quantification were developed and analyzed. First, a novel unsupervised color separation pipeline based on the IHC color histogram was proposed for the robust analysis of Ki67 and hematoxylin stained images in multicentre datasets. An “overstaining” threshold was implemented to adjust for background overstaining, and an automated nuclei radius estimator is designed to improve nuclei detection. After implementing this method, we found it to perform poorly on clinical data, specifically the nuclei detection portion. Therefore, this initiated the development of piNET, an automated Proliferation Index Calculator for Ki67 stained digital pathology images. The objective of this model was generalizability, minimal ground truth generation and robustness to multi-center datasets. In this work, a novel pipeline, piNET, can detect immuno-positive and immuno-negative tumor cells, which aids in the quantification of proliferation index. This pipeline is robust to multicenter data, has been assessed on five datasets, in order to accurately claim that the pipeline is generalizable. The F1 Scores proliferation index and classifications were thoroughly evaluated on multicenter data, 173 patched data, 90 tissue micro-arrays and 55 whole slide images. This pipeline was built on the U-NET, in combination with regression-based modeling and using a novel data partition approach. The piNET, trained on a single dataset, obtained an accuracy rate of 86% on the tissue micro-array, and 89% on patched data, and 76% on whole slide images. The proposed method can achieve an overall accuracy rate of 85% across five datasets and a Proliferation Index difference and R2 of 5.6% and 0.84 across four datasets respectively.
The Effects of Road De-Icing Salts on Two Amphibian Species, Rana Sylvatica and Rana Pipiens, and Their Trematode Parasites
Authors: Milotic Dino
Published: March 2024

With ongoing amphibian declines, it is essential to determine possible contributors such as diseases and environmental contaminants that may increase susceptibility. A potential contaminant is road salt (mainly NaCl), which leaches into aquatic environments. I examined whether road salts make larval amphibians (tadpoles) more susceptible to trematode parasite infection, and also how these affect free-living trematode infectious stages (cercariae). I exposed Rana sylvatica (wood frogs) and R. pipiens (northern leopard frogs) to control, medium (400 mg/L), and high salt (800 mg/L) treatments, and then to trematodes. High salt tended to reduce wood frog anti-parasite behaviour and resistance to infection but the opposite was seen for R. pipiens, although these tadpoles had elevated lymphocyte counts in high salinity. Trematodes were differentially affected by increased salinities. The results suggest that host-parasite-environment interactions are complex, with species differentially affected by contaminants, which may lead to community shifts in predominant hosts and parasite species.
Stałe zakłady w świetle Filarów – znaczenie analizy cen transferowych
Authors: Chand Vikram , Damji Salim , Romanovska Kinga
Published: March 2024

W artykule przeanalizowano sposób podejścia do stałych zakładów w ramach Filaru I oraz II OECD. Porusza się w nim złożoną tematykę globalnych zasad przeciwdziałania erozji podstawy opodatkowania (GloBE) oraz kwalifikowanego krajowego minimalnego podatku wyrównawczego (QDMTT) w ramach Filaru II, a także ponownego przydziału praw podatkowych w ramach Filaru I. Analizowana jest rola cen transferowych w kontekście podejścia do stałych zakładów, a w szczególności ich wpływ na obliczanie skorygowanego dochodu do celów GloBE oraz zysku eliminacyjnego. Praktyczne implikacje tych zasad dla stałych zakładów zilustrowano za pomocą studiów przypadku. W artykule podkreślono także, że potencjalnie może dochodzić do sporów, jak również potrzebę uzyskiwania zawczasu pewności w zakresie pozycji przedsiębiorstwa w kontekście cen transferowych.
Susceptibilidad antimicrobiana de bacterias causantes de infecciones del tracto urinario en mujeres y niñas
Authors: Barbecho Quizhpi Edisson Javier , Andrade Campoverde Diego
Published: March 2024

Introducción.  La infección del tracto urinario forma parte del grupo de las infecciones más frecuentes en los seres humanos, por lo que se la considera un problema de salud pública al presentar altas tasas de incidencia y morbilidad en la población pediátrica y adulta en diferentes regiones del mundo, siendo la mayor causa de estas de origen bacteriano, por lo cual los tratamientos se basan en la antibioticoterapia. Sin embargo, con el paso de los años se ha observado a nivel global el fracaso en los tratamientos empíricos debido a la resistencia bacteriana, presentando mayor incidencia países subdesarrollados. Objetivo. Caracterizar las diferentes especies bacterianas causantes de infección del tracto urinario en mujeres que acuden a consulta en la Fundación Humanitaria Pablo Jaramillo Crespo durante el año 2022, además identificar al agente causal más común y su clasificación dependiendo de si estos presentan o no la enzima betalactamasa de espectro extendido (BLEE). Metodología. Estudio descriptivo de cohorte transversal, documental secundario de muestreo no probabilístico por cobertura total. Resultados. De 304 urocultivos positivos se identificó un 62.5% casos de infección del tracto urinario en mujeres adultas y 37.5% en niñas, presentándose a Escherichia coli como el agente etiológico más común 82.2%, seguido de Proteus mirabilis 11.5%, Klebsiella pneumoniae 1.6% y 4.7% de otros microorganismos granmenegativos. Un 11.5% de casos positivos para la presencia de BLEE, siendo Escherichia coli el agente etiológico con más casos positivos para este mecanismo de resistencia con un mayor número de casos en la población infantil siendo de 21 casos. Conclusión. EL agente etiológico más común causante de Infección del tracto urinario en la población de esta casa de salud es Escherichia coli, presentándose un mayor porcentaje de casos de betalactamasa de espectro extendido en la población infantil, lo que demuestra la importancia de realizar un urocultivo y antibiograma para plantear un correcto esquema de tratamiento en los pacientes y así evitar que los microorganismos generen mecanismos de resistencia bacteriana. Área de estudio: Salud, Laboratorio clínico
Vaaterissa vai vinossa?
Authors: Junkkari Tiina
Published: March 2024

Mikään alue tai maakunta ei kehity vaikuttamatta muihin. Yhdellä alueella tapahtuva muutos johtaa muutoksiin muualla ja muuttoliikkeellä on tässä erityinen merkitys. Ammattikorkeakoulujen perustaminen lisäsi korkeakoulutuksen alueellista saavutettavuutta, mutta ei kyennyt tasaamaan eroja inhimillisen pääoman jakautumisessa alueille. Tässä artikkelissa tarkastelen kolmella suurella koulutusalalla ammattikorkeakoulututkinnon suorittaneiden nuorten muuttoliikettä maakuntien välillä. Paneudun erityisesti maakuntien väliseen nettomuuttoon vuosien 1996–2018 aikana. Tutkimukseni perustuu koulutustilastoihin ja niiden kautta väestörekisterin kotimaakuntatietoihin.Muuttovirrat poikkesivat toisistaan sekä periodein tarkasteltuna, että koulutusaloittain. Kaikilla isoilla koulutusaloilla monen maakunnan kokonaisnettomuuttovoitto perustui täysin vuosituhannen taitteessa AMK-tutkinnon suorittaneiden liikkuvuuteen. Tekniikan alalla oli selkeitä alueellisia eroja. Esimerkiksi Uudellemaalle suuntautuva nettomuuttovirtaus kasvoi jatkuvasti, kun taas Pohjois-Pohjanmaan vetovoima loppui vuoteen 2007 mennessä. Terveysalalla vetovoimaisin ja jatkuvasti kasvava maakunta oli Pirkanmaa. Kokonaiskuvassa Lappi, Kainuu, Keski-Pohjanmaa, Pohjanmaa ja Satakunta eivät olleet millään koulutusalalla nettomuuttovoittajia mihinkään toiseen maakuntaan nähden.
Lasten osallisuuden mahdollisuudet kuvataiteen traditioissa
Authors: Moilanen Jaakko H. , Juutinen Jaana , Siippainen Anna
Published: March 2024

Tässä artikkelissa tarkastelemme varhaiskasvatuksen opettajien kuvauksia onnistuneesta kuvataidekasvatustoiminnasta. Olemme kiinnostuneita erityisesti siitä, millaisena osallisuus kuvataan toiminnassa ja miten osallisuus on suhteessa kuvataidekasvatuksen traditioihin. Osallisuus ymmärretään tutkimuksessa sosiaalisena ja poliittisena ilmiönä, jossa korostuvat yhteisöllisyys, yhteisöön kuuluminen ja yhteisössä toimiminen, päätösten tekeminen ja -tekoprosessit sekä vaikuttaminen. Aineisto on kerätty osana Kansallisen koulutuksen arviointikeskuksen toteuttamaa arviointia, jossa tarkasteltiin viisivuotiaiden pedagogiikkaa ja taito- ja taidekasvatuksen tilaa varhaiskasvatuksessa. Analyysimenetelmänä tutkimuksessa hyödynnettiin abduktiivista sisällönanalyysiä, jota on toteutettu sekä laadullisena että määrällisenä. Tulosten mukaan varhaiskasvatuksen kuvataiteessa korostuu aikuisjohtoisuus ja kuvataidetta toteutetaan usein menetelmälähtöisesti. Varhaiskasvatussuunnitelman sekä esiopetuksen opetussuunnitelman perusteiden tavoitteet osallisuuden sekä kuvallisen ilmaisun osalta jäävät vähälle huomiolle.
Optimalisasi manajemen pembelajaran dalam keberhasilan kurikulum merdeka
Authors: Zuhriyah Indah Aminatuz , Padil Moh. , Rabbani Imdad
Published: March 2024

Kebijakan Kurikulum merdeka yang dianggap sebagai langkah dalam menggapai pendidikan yang berkualitas masih jauh dari pemahaman para stakeholder pendidikan. Sehingga tujuan penelitian dalam pengabdian masyarakat ini ialah pendampingan (workshop) pengembangan manajemen pembelajaran dalam mengaktualisasikan kurikulum merdeka di SMA An-Nur Malang. Metode penelitian menggunakan action research model yang bermanfaat untuk memfasilitasi dan memotivasi agar komunitas sekolah khususnya guru-guru mampu menyusun strategi dan metode yang tepat untuk memecahkan permasalahan para guru dalam mengembangkan manajemen pembelajaran pada implementasi merdeka belajar dan menyusun rencana aksi berdasarkan prioritas, dan keberlanjutan program melalui tahapan-tahapan hingga mencapai target yang diharapkan. Sebagai tindak lanjut dari penyelenggaraan Pengabdian Kepada Masyarakat dalam bentuk pendampingan pembelajaran dalam implementasi kurikulum merdeka di SMA An Nur Bululawang Malang, sekolah perlu meningkatkan wawasan dan pemahaman tentang kurikulum merdeka melalui pelaksanaan workshop yang dipraktekkan langsung oleh tenaga tutor serta fasilitator yang sangat mumpuni. Sehingga tujuan nasional pendidikan melalui penerapan kurikulum merdeka belajar akan dapat dicapai serta mampu menciptakan lulusan yang kompeten sesuai dengan perkembangan ilmu pengetahuan dan teknologi sampai saat ini.
RECENZIA / REVIEW SLEZÁKOVÁ, A., HAJNIŠOVÁ, E., MIKLOŠ, P. a kol. SPOLOČNOSŤ S RUČENÍM OBMEDZENÝM VYKONÁVAJÚCA ČINNOSŤ SAMOSTATNÉHO FINANČNÉHO AGENTA.
Authors: Ayrumyan Gevorg
Published: March 2024

Bratislava: Wolters Kluwer SR, 2023, ISBN: 978-80-571- 0588-6, s. 184.
Determination of Early Diagnostic Biomarkers of Renal Dysfunction After Cardiopulmonary Bypass: miR-21 and miR10a Mediated Postoperative Inflammation
Authors: Çağıl Fatma Zehra , Ak Koray , Rafiqi Ab. Matteen , Saraçoğlu Ayten , Öter Gamze Nur , Tetik Şermin
Published: March 2024

Objective: Acute renal failure (ARF) prevalence is high among patients who undergo cardiopulmonary bypass (CPB), and this condition can only be diagnosed via serum creatinine level (sCr) conventionally within 48 hours. Therefore, we need early novel diagnosis biomarkers to start preventive treatment of ARF. For that reason, we aimed to analyze if plasma miR-21 derived from heart, correlates with kidney- enriched miR-10a during inflammatory IL-6, IL-1β, and TNF-α response in terms of acute renal failure 30 minutes after CPB.
Methods: Patients (n=46, Female:8 and Male:38), aged 61.08±9.41, who underwent CPB surgery were included. Blood samples were collected during the pre – and post-CPB (30 minutes after CPB). Demographic data of all cases were collected. Quantification of expression levels of miR-21 and miR-10a was done via quantitative PCR (qPCR). Determination of plasma concentration of relevant cytokines, IL-6, IL-1β, and TNF-α was done via ELISA.
Results: The circulating level of miR-21 during post-CPB period (-11.78±6.98) was significantly higher (p≤0.05) than pre-CPB period (-6.55±7.11), but there was no significant change (p>0.05) in the circulating level of miR-10a between pre – (-12.22±3.55) and post-CPB (-11.60±3.36) periods. When we compared the mean ΔΔCt values of miR-21 and miR-10a, downregulation was observed in the expression level of miR-10a (0.62±3.77) whilst the expression level of miR-21 (-5.22±7.25) was upregulated (p≤0.05). The levels of plasma concentration of IL-6 (2.74±2.50 ng/l) and TNF-α (83.63±9.33 ng/l) were increased during post-CPB period (both were ***p
PENGABDIAN MASYARAKAT MELALUI PEMBERIAN PENDIDIKAN KESEHATAN PENTINGNYA KESEHATAN MENTAL DAN EMOSIONAL REMAJA SMA
Authors: Fitri Nurwijaya , Mardiana Nova , Sari Indah Permata
Published: March 2024

Menurut Badan Kesehatan Dunia tahun 2018, remaja adalah individu yang masuk di kisaran usia 10-19 tahun, berdasarkan Peraturan Menteri Kesehatan Republik Indonesia (Permenkes RI) nomor 25 tahun 2014, remaja merupakan seseorang yang berada direntang usia 10-18 tahun. Menurut World Health Organization (2020), angka kejadian permasalahan gangguan kesehatan mental di dunia dengan rentang remaja usia 10 sampai 19 tahun dan terus terjadi peningkatan 16% setiap tahunnya. Gangguan kesehatan mental yang terjadi diawali usia mulai dari 14 tahun, dan yang terjadi mayoritas kasus yang terdeteksi sangat minim sekali dan perlu di lakukan pencegahan  sejak dini.  Terlepas dari semua masalah kesehatan mental tersebut, remaja yang sedang memasuki masa pubertas sangat beresiko dan paling rentan mengalami gangguan kesehatan jika tidak dapat beradaptasi dan memanajemen masalah yang di hadapi. Berdasarkan hasil wawancara dengan salah satu remaja di SMA tempat pengabdian, didapatkan informasi bahwa siswa tersebut belum pernah mendapatkan informasi terkait pentingnya menjaga kesehatan mental dan emosional. Tujuan dari kegiatan ini yaitu untuk menambah informasi, knowledge dan kemampuan remaja SMA tentang pentingnya menjaga kesehatan mental dan emosional. Kegiatan pengabdian ini dilaksanakan dalam bentuk sosialisasi, pretest, pendidikan kesehatan menggunakan powertpoint, leaflet dan posttest. Kegiatan diikuti oleh remaja SMA Bahrul Ulum Sungailiat berjumlah 40 orang. Hasil kegiatan ini menggambarkan adanya peningkatan pengetahuan Remaja dalam hal informasi pentingnya menjaga kesehatan mental dan emosional dengan selisih nilai pre dan  posttest  sebesar 20%. Kesimpulan dengan pengaplikasian pendidikan kesehatan pada remaja sangat efektif dalam hal meningkatkan informasi, pengetahuan dan  diharapkan kegiatan ini bisa berimplikasi terhadap pengetahuan dan motivasi remaja terkait pentingnya menjaga kesehatan mental dan emosional sejak dini.
CONHECIMENTO DAS ADOLESCENTES DO COLÉGIO JOSÉ MARCOS GUSMÃO DO MUNICÍPIO DE ITAPETINGA – BA SOBRE O HPV E A PREVENÇÃO DO CÂNCER DE COLO UTERINO
Authors: De Carvalho Amarildo Vieira , Almeida Obertal da Silva , Scaldaferri Murilo Marques
Published: March 2024

O câncer de colo uterino apresenta alta mortalidade no Brasil, apesar dos programas para rastreamento. Entre todos os tipos de câncer, é o que apresenta um dos mais altos potenciais de prevenção e cura, quando diagnosticado precocemente pelo exame Papanicolaou. O iní­cio sexual cada vez mais cedo e a promiscuidade propicia alta vulnerabilidade da adolescente a problemas da esfera sexual/reprodutiva. Nesse sentido este trabalho tem como objetivo avaliar o ní­vel de conhecimento das adolescentes em um colégio municipal sobre a prevenção do câncer de colo uterino e HPV. A pesquisa foi realizada no Colégio Municipal José Marcos Gusmão localizado no Municí­pio de Itapetinga, BA, com uma amostra 160 adolescentes do gênero feminino. A coleta dos dados foi feita por meio da aplicação de um questionário. As adolescentes apresentaram uma visão muito escassa sobre DST, HPV, CCU e outras manifestações do corpo a partir desta fase, e o pouco que foi abordado por elas nesta pesquisa demonstrou que é na escola que ouviram falar sobre esses temas.
JOSEPH WRIGHT, PIBID E A FORMAÇÃO DE PROFESSORES DE FÍSICA: ALGUMAS REFLEXÕES PERTINENTES
Authors: Miquelin Awdry Feisser
Published: March 2024

Este trabalho trata de uma reflexão crí­tica2 em torno da natureza do Programa Institucional de Bolsa de Iniciação a Docência (PIBID)3. No mesmo propõe-se um paralelo entre o trabalho de criação artí­stico de Joseph Wright, pintor inglês do século XVIII e o possí­vel processo de formação de professores de Fí­sica desencadeado pelo PIBID. Para tanto argumenta-se em torno da criação da tela "An experiment of a bird in an airpump" e são apresentadas algumas reflexões em relação, a algumas controvérsias vividas, em como o PIBID pode atuar junto a escola básica. Para tanto apresentam-se as inquietações oriundas do processo vivido no curso de licenciatura de Fí­sica da instituição analisada e coloca-se Freire, Carr e Kemmis e Ramalho, Nuñez e Gauthier como núcleo principal para nortear a implementação e prática do PIBID nas escolas participantes. Disto apresentamos como resultado, o sistema de organização de trabalho baseado em árvores temáticas e na espiral de ciclos auto-reflexiva, a inserção dos bolsistas em dinâmicas investigativo-acadêmicas, o aprendizado formativo intenso mediante confronto da realidade escolar e pesquisa em ensino de Fí­sica, o amadurecimento da concepção da prática em ensino de Fí­sica e o aumento na segurança em ser professor de Fí­sica. Disto coloca-se que o PIBID pode ser um instrumento para a formação de professores de Fí­sica em um paradigma emergente e que neste, o paralelo entre o trabalho artí­stico é possí­vel, pois o PIBID pode constituir um palco de experimentação para a formação de professores curiosos e criativos em busca de conhecimento diferenciado para o ensino-aprendizagem de Fí­sica.
DO RISO AO ESCÁRNIO UMA ANÁLISE ANIMADA PARA AS AULAS DE FILOSOFIA
Authors: Gomes Fábio Augusto
Published: March 2024

O presente trabalho, de caráter bibliográfico, tem como objetivo analisar os desenhos animados, Os Simpsons (Matt Groening) e South Park (Tray Parker e Matt Stone) a luz da filosofia, com ênfase para o ensino da disciplina. Durante todo o percurso histórico o riso foi considerado ora demoní­aco, ora angelical, ora expressão de alegria e felicidade, ora fruto do desdém por outrem. No teatro grego a comédia tinha como pressuposto demonstrar os excessos do humano, suas vicissitudes e defeitos em contraponto com a tragédia que exaltava o humano e o processo catártico deste para uma vida contemplativa, mais alta honraria para o cidadão. Desta forma o escárnio era uma caracterí­stica da comédia e das festas dionisí­acas. Tomado como diabólico na idade média ressurge na renascença com vigor, a partir de François Rabelais. Os séculos XVII e XVIII exorcizam os entes do mal que o riso trouxe do medievo, ou simplesmente aceitam que o riso, mesmo diabólico, não é tão mal assim; com Moliére o poder ácido do espí­rito maledicente toma conta de seu tempo caricaturando personagens célebres e utilizando o escárnio como arma polí­tica e social; ganha os contornos atuais. Entretanto o poder do riso e do escárnio foi utilizado durante toda a história da filosofia, tendo Nietzsche como exemplo. A ironia socrática, mãe do riso, foi exaltada como método para obtenção de verdades, porém é com Nietzsche, a exaltação do Dionisí­aco sobre o Apolí­neo, que a derrisão ganha à pertença humana o reino dos instintos, um retorno aos defeitos e vicissitudes da vida e do viver. Delineados estes caminhos, analisar-se-á os respectivos desenhos animados como ferramentas reflexivas para o ensino de filosofia, visto que o humor corrosivo de ambos colocam em xeque valores sociais, culturais, polí­ticos e religiosos, a partir de crí­ticas mordazes sobre o cotidiano e o politicamente correto, contextualizando o ensino da filosofia a partir da trivialidade dos acontecimentos mundanos.
Climograma Lúdico: Proposta de Recurso Didático para o Ensino do Clima nas Aulas de Geografia
Authors: Pontes de Oliveira Neto Vicente , Do Carmo Judite De Azevedo , Peretto Anderson
Published: March 2024

O objetivo da Geografia escolar é contribuir para a formação do cidadão. Para tanto, se faz necessário considerar o aluno como sujeito do processo de ensino-aprendizagem, o saber cientí­fico precisa estar acessí­vel ao educando por meio de uma linguagem que ele entenda. Porém, a falta de conhecimento e insegurança dos professores em relação aos novos métodos de ensino, faz com que na atualidade ainda se encontre ações pedagógicas fundamentadas na Geografia tradicional, onde o professor proporciona um ensino baseado na mera transmissão de conteúdo. No ensino do clima é possí­vel identificar grandes dificuldades em tratá-lo de uma forma integrada ao cotidiano do estudante, bem como uma superficialidade em sua abordagem nos livros didáticos. Diante desta realidade, procurou-se por meio de revisão bibliográfica e observação do dia a dia de sala de aula em uma escola Estadual da cidade de Colider-MT, por intermédio do Programa Institucional de Bolsa de Iniciação à Docência (PIBID), apresentar o climograma lúdico como recurso didático para as aulas de geografia, por entender que este proporciona ao aluno transformar-se em protagonista do processo de ensino-aprendizagem.
Design of a simplified cranial substitute with a modal behavior close to that of a human skull
Authors: Elster Natacha , Boutillier Johanna , Bourdet Nicolas , Magnan Pascal , Naz Pierre , Willinger Rémy , Deck Caroline
Published: March 2024

Individuals exposed to the propagation of shock waves generated by the detonation of explosive charges may suffer Traumatic Brain Injury. The mechanism of cranial deflection is one of many hypotheses that could explain the observed brain damage. To investigate this physical phenomenon in a reproducible manner, a new simplified cranial substitute was designed with a mechanical response close to that of a human skull when subjected to this type of loading. As a first step, a Finite Element Model was employed to dimension the new substitute. The objective was indeed to obtain a vibratory behavior close to that of a dry human skull over a wide range of frequencies up to 10 kHz. As a second step, the Finite Element Model was used together with Experimental Modal Analyses to identify the vibration modes of the substitute. A shaker excited the structure via a metal rod, while a laser vibrometer recorded the induced vibrations at defined measurement points. The results showed that despite differences in material properties and geometry, the newly developed substitute has 10/13 natural frequencies in common with those of dry human skulls. When filled with a simulant of cerebral matter, it could therefore be used in future studies as an approximation to assess the mechanical response of a simplified skull substitute to a blast threat.
Fungus-mediated synthesis of Se-BiO-CuO multimetallic nanoparticles as a potential alternative antimicrobial against ESBL-producing Escherichia coli of veterinary origin
Authors: Rasheed Rida , Uzair Bushra , Raza Abida , Binsuwaidan Reem , Alshammari Nawaf
Published: March 2024

Bacterial infections emerge as a significant contributor to mortality and morbidity worldwide. Emerging extended-spectrum β-lactamase (ESBL) Escherichia coli strains provide a greater risk of bacteremia and mortality, are increasingly resistant to antibiotics, and are a major producer of ESBLs. E. coli bacteremia-linked mastitis is one of the most common bacterial diseases in animals, which can affect the quality of the milk and damage organ functions. There is an elevated menace of treatment failure and recurrence of E. coli bacteremia necessitating the adoption of rigorous alternative treatment approaches. In this study, Se-Boil-CuO multimetallic nanoparticles (MMNPs) were synthesized as an alternate treatment from Talaromyces haitouensis extract, and their efficiency in treating ESBL E. coli was confirmed using standard antimicrobial assays. Scanning electron microscopy, UV–visible spectroscopy, and dynamic light scattering were used to validate and characterize the mycosynthesized Se-BiO-CuO MMNPs. UV–visible spectra of Se-BiO-CuO MMNPs showed absorption peak bands at 570, 376, and 290 nm, respectively. The average diameters of the amorphous-shaped Se-BiO-CuO MMNPs synthesized by T. haitouensis extract were approximately 66–80 nm, respectively. Se-BiO-CuO MMNPs (100 μg/mL) showed a maximal inhibition zone of 18.33 ± 0.57 mm against E. coli. Se-BiO-CuO MMNPs also exhibited a deleterious impact on E. coli killing kinetics, biofilm formation, swimming motility, efflux of cellular components, and membrane integrity. The hemolysis assay also confirms the biocompatibility of Se-BiO-CuO MMNPs at the minimum inhibitory concentration (MIC) range. Our findings suggest that Se-BiO-CuO MMNPs may serve as a potential substitute for ESBL E. coli bacteremia.
Significance of the Wnt signaling pathway in coronary artery atherosclerosis
Authors: Khan Kashif , Yu Bin , Tardif Jean-Claude , Rhéaume Eric , Al-Kindi Hamood , Filimon Sabin , Pop Cristina , Genest Jacques , Cecere Renzo , Schwertani Adel
Published: March 2024

Introduction

The progression of coronary atherosclerosis is an active and regulated process. The Wnt signaling pathway is thought to play an active role in the pathogenesis of several cardiovascular diseases; however, a better understanding of this system in atherosclerosis is yet to be unraveled.

Methods

In this study, real-time quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) and Western blotting were used to quantify the expression of Wnt3a, Wnt5a, and Wnt5b in the human coronary plaque, and immunohistochemistry was used to identify sites of local expression. To determine the pathologic significance of increased Wnt, human vascular smooth muscle cells (vSMCs) were treated with Wnt3a, Wnt5a, and Wnt5b recombinant proteins and assessed for changes in cell differentiation and function.

Results

RT-PCR and Western blotting showed a significant increase in the expression of Wnt3a, Wnt5a, Wnt5b, and their receptors in diseased coronary arteries compared with that in non-diseased coronary arteries. Immunohistochemistry revealed an abundant expression of Wnt3a and Wnt5b in diseased coronary arteries, which contrasted with little or no signals in normal coronary arteries. Immunostaining of Wnt3a and Wnt5b was found largely in inflammatory cells and myointimal cells. The treatment of vSMCs with Wnt3a, Wnt5a, and Wnt5b resulted in increased vSMC differentiation, migration, calcification, oxidative stress, and impaired cholesterol handling.

Conclusions

This study demonstrates the upregulation of three important members of canonical and non-canonical Wnt signaling pathways and their receptors in coronary atherosclerosis and shows an important role for these molecules in plaque development through increased cellular remodeling and impaired cholesterol handling.