bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular epidemiology of Human Rhinoviruses in children in Hong Kong, 2020-2021
Authors: Gurung Shreya , Edwards Kimberly , Chan Eunice , Poon Leo , Lee So-Lun , Chiu Susan , Cowling Benjamin , Dhanasekaran Vijaykrishna
Published: July 2023

Background COVID-19 related public health and social measures (PHSMs)
worldwide have influenced respiratory virus epidemiology. In Hong Kong,
paediatric hospitalisations associated with non-COVID-19 respiratory
viruses declined in 2020. As PHSMs eased, rhinoviruses/enteroviruses
became the primary detected respiratory viruses. This study examines the
genetic diversity in resurgent human rhinovirus (HRV) cases. Methods We
sequenced rhinovirus/enterovirus samples from children at Queen Mary
Hospital, Hong Kong, between August 2020 and October 2021 to estimate
changes in HRV genotypes and describe their epidemic characteristics.
Whole genome sequencing was performed on the three most prevalent HRV
genotypes to infer patterns of virus introduction and persistence.
Results Despite reduced respiratory virus circulation, HRV type A and C
infections persisted in children, with sporadic detection of HRV B and
other respiratory viruses. A resurgence of HRV A cases in November 2020,
dominated by genotypes A47 and A101, was observed during the relaxation
of PHSMs between the third and fourth waves of COVID-19. Strict PHSMs
implemented during the fourth wave, including school closures,
substantially reduced respiratory virus circulation, though overall
diversity increased due to heightened vigilance. HRV genotype A49 became
predominant in May 2021 upon relaxation of control measures, with
phylogenetic analysis suggesting persistence of multiple transmission
lineages despite strict PHSMs. Genotypes A49 and A47 were frequently
associated with upper respiratory tract infections, highlighting their
epidemic potential. Conclusion This study underscores the impact of
control measures on HRV genetic diversity and highlights the need for
continuous surveillance and sequencing to inform public health
interventions.
Rapid visual nucleic acid detection of Vibrio alginolyticus by RPA combined with CRISPR/Cas13a
Authors: Wang Yanan , Hou Yachao , Liu Xinping , Lin Na , Dong Youyou , Liu Fei , Xia Wenrong , Zhao Yongqi , Xing Weiwei , Chen Jin , Chen Changguo
Published: July 2023

Vibrio alginolyticus ( V. alginolyticus) is a common
pathogen that infects humans and animals. In addition to causing serious
economic losses in aquaculture, it can also infect humans. The rapid
detection of nucleic acids of V. alginolyticus with high
sensitivity and specificity in the field is very important for the
diagnosis and treatment of infection caused by V. alginolyticus.
Here, we established a simple, fast and effective molecular method for
the identification of V. alginolyticus that does not rely on
expensive instruments and professionals. The method integrates RPA
technology with CRISPR technology in a single PCR tube. Using this
method, the results can be visualized by lateral flow dipstick in less
than 50 minutes. The method was confirmed to achieve high specificity
for the detection of V. alginolyticus with no cross-reactivity
with similar Vibrio and common clinical pathogens. This
diagnostic method shows high sensitivity; the detection limit of the
RPA-CRISPR/Cas13a-LFD is 10 copies µL . The results
for 55 wild strains were consistent with TaqMan-qPCR, and it can be
concluded that the methods have 100% sensitivity and 100% specificity.
In conclusion, RPA-CRISPR/Cas13a offers great potential as a useful tool
for reliable and rapid diagnosis of V. alginolyticus infection,
especially in limited conditions.
Guest editorial: Advances in intelligent data, data engineering, and information systems
Authors: Halfeld Ferrari , Ceravolo Paolo , Ristic Sonja , Jararweh Yaser , Katsaros Dimitrios
Published: July 2023

nema
Sex-specific differences in the epidemiology, progression, and outcomes of chronic kidney disease
Authors: Djukanovic Ljubica , Dimkovic Nada , Lezaic Visnja
Published: July 2023

Higher prevalence of chronic kidney disease (CKD) in women than in men was reported all over the world. This difference could be partly explained by longer life expectancy and slower CKD progression rate in women. Potential factors associated with sex differences in CKD progression are as follows: difference in glomerular hemodynamic and the response to angiotensin II; sex hormones ? estrogen has protective and testosterone deleterious effects on CKD progression; lifestyle. In most countries, the percentage of men is higher than that of women among incident and prevalent patients on hemodialysis (HD). In HD patients, the Kt/V index overestimates HD adequacy, secondary hyperparathyroidism is more common in women, and women require higher doses of erythropoiesis-stimulating agents for achieving and maintaining the hemoglobin target level. The survival of HD patients is equal for both sexes. In earlier years, an equal percentage of women and men started peritoneal dialysis, but in recent years, a higher percentage of women, especially at younger ages, start peritoneal dialysis. Initial peritoneal transport properties differ between men and women. A smaller percentage of women than men receive deceased donor kidneys, but women are more likely to be living kidney donors. Kidney allograft outcome depends on the sex and age of both the recipient and the donor. Cardiovascular diseases are the most common cause of death for renal replacement therapy patients of both sexes. Although sex-specific differences have been described in CKD patients, the inequality of patients in access to medical care has not been found in most regions of the world.
Transformaciones proyectadas para gestionar el proceso contable de la Universidad de La Habana con calidad
Authors: Naveira Brito Roberto , Martín Sabina Elvira , Pozo Ceballos Sergio
Published: July 2023

La gestión contable de la Universidad de La Habana (UH) requiere transformaciones en su accionar para lograr un nivel cualitativo superior, es por ello que, el objetivo de la presente investigación es proponer los elementos sujetos a mejora y las acciones a desarrollar para contribuir al perfeccionamiento de la gestión del proceso contable. En el desarrollo del trabajo se abordan los elementos teóricos que sustentan la investigación y se expone el contexto en el que se desarrolla la gestión contable. Se aplicó una encuesta al personal calificado de las direcciones de Economía de la Unidad Presupuestada de Aseguramiento a la Universidad de La Habana (UPAUH) y de la UH para actualizar el diagnóstico de la situación del proceso contable y determinar las principales fortalezas y debilidades asociadas al mismo. Los resultados obtenidos permitieron concluir que existen debilidades relacionadas con la gestión del capital humano, el manual de contabilidad y el diseño de la gestión del proceso contable, sobre las que se debe incidir aprovechando las potencialidades asociadas al compromiso del personal para lograr la calidad del proceso contable. En consecuencia, se proponen las acciones a realizar en estos tres aspectos que fundamentan el rediseño de la gestión del proceso contable en la UH.
Formación articulada con la agenda 2030 en asignaturas de la carrera Ciencias de la Información
Authors: Rodríguez Fernández Rosa , Aguilera Rodríguez María , Licea Jiménez Idanea , Peña Borrego Maida
Published: July 2023

La Educación Superior Cubana debe trabajar por hacer que los estudiantes se sientan copartícipes del cumplimiento de la Agenda 2030 y los objetivos de desarrollo sostenible; una vía para lograrlo es la aplicación de métodos colaborativos de aprendizaje que vinculen la formación con los problemas de desarrollo en los territorios. El trabajo se enfoca en la formación de los profesionales de las Ciencias de la Información vinculado fundamentalmente al objetivo 8 de la Agenda “Promover el crecimiento económico sostenido, inclusivo y sostenible, el empleo pleno y productivo y el trabajo decente para todos”. Se muestra cómo desde diferentes asignaturas impartidas en las universidades de La Habana y Holguín, se prepara a los estudiantes para participar en el cumplimiento de los Objetivos de Desarrollo Sostenible (ODS). Se aplicó el análisis documental clásico para el fundamento teórico y la consulta de los programas de las asignaturas como sustento de las reflexiones que se presentan. Se concluyó que es posible utilizar diferentes técnicas didácticas activas tanto presenciales como virtuales para desarrollar habilidades colaborativas en la resolución de los problemas de desarrollo; que en ambas universidades se ha incrementado el tratamiento de los ODS como parte de la formación de los estudiantes de la carrera y que las actividades planificadas en las asignaturas permiten a los estudiantes identificarse como actores del desarrollo donde asumen diferentes roles, tanto como creadores de productos y servicios informativos como empoderando a los individuos al capacitarlos para una mejor gestión de la información en todos los escenarios.
Development Of Video Learning Based On The Indonesian Language Signing System (SIBI) Method For Class II Deaf Chill At SDN 2 Bengkala Academic Year 2022/2023
Authors: Intan Wahyuni Ni Kadek , Suarjana I Made , Puteri Handayani Dewa Ayu
Published: July 2023

This research is development research (research and development). The product developed is Learning Video Media Based on the SIBI Method for Deaf Children, Grade II. This study aims to (1) determine the design of learning video media based on the SIBI method for grade II deaf students; (2) determine the validity of learning video media based on the SIBI method for grade II deaf children; and (3) determine the response of deaf students to learning video media based on the SIBI method for grade II deaf children. The 4D (four-D) model is a method used in the process of developing learning videos based on the SIBI method. The data collection method used is a questionnaire, which is then filled out by the respondents. Data analysis methods and techniques used in this research are qualitative and quantitative descriptive statistical analysis. In this SIBI method-based learning video media obtained a validation score by learning media experts of 94.5% (very good), then the validity test score by learning material experts was 97.85% (very good), then the results of media assessment through practitioner/teacher responses were 93.5% (very practical), and through student responses, a score of 86% (good). It is concluded that this development research obtained results with very good and very practical qualification levels, so that the products produced are feasible to be applied and used in the learning process for deaf children in grade II SDN 2 Bengkala
Analysis of Reading Ability in Terms of Parenting Patterns in Grade I Students (Case Study in Elementary School Gugus V Seririt District 2022/2023 Academic Year)
Authors: Aryawan Kadek Agung Sugi
Published: July 2023

The problem in this study is that the reading ability experienced by grade I students is still low. Teachers at school have provided maximum guidance at school, but students not only learn at school, but students can also learn at home with their parents. Students have more time studying at home with parental guidance than when they study at school. The form of parenting applied by parents greatly affects the development of children, especially in terms of reading. This study aims to determine the factors that influence the reading ability of grade I students and the form of parenting applied by parents at home case study in SD Gugus V, Seririt District, Buleleng Regency. This type of research is descriptive qualitative research using the case study method. The sample determination used purposive sampling technique with a total sample size of 7 student subjects and 7 student parent subjects. Data collection used non-test methods in the form of observation, interviews, questionnaires, and documentation. The data analysis technique uses 2 techniques, namely qualitative descriptive analysis and quantitative description analysis. The results of the data analysis of this study found that the percentage score on the factors that influence reading ability in both aspects is described as follows: 1) internal factors with a percentage score of 69%, and 2) external factors with a percentage score of 72%. Meanwhile, the score of parenting patterns in the three aspects is different. Each aspect is described as follows: 1) authoritarian parenting has a percentage score of 65%, 2) democratic parenting has a percentage score of 78%, and 3) permissive parenting has a percentage score of 66%. From these results, it can be concluded that most parents have applied democratic parenting in educating their children, but the factors that greatly affect the reading ability of most students are external factors.
Development and Implementation of Blockchain Solution to Enable Data Security at University of Port Harcourt
Authors: Enoch Joseph D. , Omijeh Bourdillon O. , Okeke Remigius O.
Published: July 2023

Institutions globally, seek for a solution that intelligently manages the security of data without tampering or mutilations. To compete globally, It has become necessary for the educational sector in Nigeria to build a software solution to end the challenges of fake results, transcripts and certificates and the time it takes to verify their authenticity. This research aims to develop and implement a blockchain solution that would enforce the required security for the Centre for Information and Telecommunication Engineering, University of Port Harcourt (CITE, Uniport), Nigeria. In this study the various services that comprise the building of a decentralized blockchain network, the network consensus algorithm and block explorer application as a unit was put together using JavaScript and its associate libraries. The blockchain data structure was developed with the ability of proof of work, the mining of new blocks, the creation of transactions, the validation of the chain, retrieving the data and other functionalities when demanded. The decentralized blockchain network was developed and tested for ten API (application programming interface) servers and the result shows that the blocks and transactions created were broadcasted throughout the entire network. The results of the consensus algorithms proved that it was able to verify and ensure that the network nodes have valid data and are synchronized. The blockchain explorer application was implemented with a lot of features. It allow user to query the blockchain for specific blocks, results, transcript or certificate.
Inventarisasi Hama Lalat Buah (Bactrocera spp) di SKP Kelas I Bengkulu Wilker Pulau Baai Dengan Perangkap Methyl Eugenol
Authors: Pratiwi Selsa Nisa , Fatimatuzzahra Fatimatuzzahra , Marniati Hesti , Isnawan Yunus
Published: July 2023

This study aims to determine the type of fruit fly (Bactrocera spp) that attacks several fruit plants. Class I Bengkulu. Sampling was carried with random sampling technique. The methods used is descriptive eksploratory. The results of this study were obtained, there are 4 species of Bactrocera spp that attack several fruit plants, namely Bactrocera albistrigata, Bactrocera cucurbitae, Bactrocera umbrosa, and Bactrocera papayae with characteristics on the abdomen, thorax, and wingsAbstrakPenelitian ini bertujuan untuk mengetahui jenis lalat buah (Bactrocera spp) yang menyerang beberapa tanaman buah. Pengambilan sampel dilakukan di Stasiun Karantina Pertanian Kelas I Bengkulu dengan teknik random sampling. Metode yang digunakan, yaitu deskriptif eksploriatif. Hasil penelitian ini didapatkan 4 spesies Bactrocera spp yang menyerang beberapa tanaman buah, yaitu Bactrocera albistrigata, Bactrocera cucurbitae, Bactrocera umbrosa, dan Bactrocera papayae dengan ciri utama pembeda terletak pada bagian abdomen, toraks, dan sayap
Beberapa Tumbuhan yang Berpotensi Sebagai Anti-Skabies di Indonesia
Authors: Septiani Linda , Pertiwi Primasari , Andrifianie Femmy , Marcellia Selvi , Damayanti Ervina
Published: July 2023

Scabies is a type of parasitic infectious disease of the skin caused by the mite Sarcoptes scabiei var hominis.  Scabies is often found in areas with high population density, low economic status, poor sanitation and hygiene. For now, medication is one of the factors inhibitors in the treatment of scabies. This happened because chemical drugs has several effects such as contraindications, irritation, toxicity, and is not effective to all mite stages. Therefore, alternative treatments are needed that come from natural ingredients by exploring various plants in Indonesia that potential to have an active compounds to eradicate mites. The aims of this study is to summarize some of the result of research on alternative plant based anti-scabies and give the information as a reference for further research. This study uses the literature study method to obtain information from several research journal. Based on the results of a literature search, it was found that 15 plant species were extracted and tested on animals and humans which contain active compounds and have the potential as anti-scabies. These fifteen plants can grow well in the territory of Indonesia, so that people can cultivate them and develop them as natural anti-scabies agents. AbstrakSkabies merupakan salah satu jenis penyakit infeksi parasit pada kulit yang disebabkan oleh tungau Sarcoptes scabiei var hominis. Skabies banyak ditemukan di daerah dengan kepadatan penduduk yang tinggi, status ekonomi rendah, sanitasi dan hygiene yang buruk. Saat ini, pengobatan dengan bahan kimia menjadi salah satu faktor yang menjadi penghambat dalam penanggulangan skabies. Hal tersebut terjadi karena obat kimia memiliki beberapa efek seperti kontraindikasi, iritasi, toksik, dan tidak efektif terhadap semua stadium tungau. Oleh karena itu, diperlukan alternatif pengobatan yang berasal dari bahan alam dengan mengeksplorasi berbagai tumbuhan di Indonesia yang berpotensi memiliki senyawa aktif untuk membasmi tungau. Tujuan studi ini adalah merangkum beberapa hasil penelitian tentang obat alternatif anti skabies berbahan dasar tumbuhan dan memberikan informasi dasar sebagai referensi penelitian lebih lanjut. Penelitian ini menggunakan metode studi literatur untuk memperoleh informasi dari beberapa jurnal penelitian. Berdasarkan hasil penelusuran pustaka diperoleh 15 jenis tumbuhan yang di ekstrak dan di uji ke hewan maupun manusia yang memiliki kandungan senyawa aktif dan berpotensi sebagai anti skabies. Kelima belas tanaman tersebut dapat tumbuh dengan baik dengan di wilayah Indonesia, sehingga masyarakat dapat membudidayakannya dan mengembangkannya sebagai bahan anti-skabies alami.
Сознание: между психопатией и шизофренией
Authors: Мерзляков Сергей
Published: July 2023

Вопрос о функции сознания является частью «трудной проблемы сознания» и фокусирует внимание на гипотетической роли феноменальных данных, то есть на определении момента актуализации сознания. В настоящее время не существует общепризнанных представлений о том, какую роль сознание играет в жизни человека. Дискуссионными являются вопросы об эволюционной причине появления сознания и распространении сознания среди отличных от человека объектов мира. При этом в теории сознания недостаточно внимания уделяется вопросу о степени реализации функции сознания. Допустимо, что гипотетическая функция сознания может по-разному реализовываться у людей. Подобная постановка вопроса позволяет внести коррективы в методологию поиска физиологических коррелятов сознательных действий; под другой оптикой посмотреть на проблему нечеловеческих носителей сознания; выйти в пространство этических дискуссий. В статье обосновывается потенциал исследовательского движения в этом направлении изучения сознания на примере воображения как гипотетической функции сознания.

Ключевые слова: сознание, воображение, трудная проблема сознания, психопатия, шизофрения, функция сознания

Аннотация

Вопрос о функции сознания является частью «трудной проблемы сознания» и фокусирует внимание на гипотетической роли феноменальных данных, то есть на определении момента актуализации сознания. В настоящее время не существует общепризнанных представлений о том, какую роль сознание играет в жизни человека. Дискуссионными являются вопросы об эволюционной причине появления сознания и распространении сознания среди отличных от человека объектов мира. При этом в теории сознания недостаточно внимания уделяется вопросу о степени реализации функции сознания. Допустимо, что гипотетическая функция сознания может по-разному реализовываться у людей. Подобная постановка вопроса позволяет внести коррективы в методологию поиска физиологических коррелятов сознательных действий; под другой оптикой посмотреть на проблему нечеловеческих носителей сознания; выйти в пространство этических дискуссий. В статье обосновывается потенциал исследовательского движения в этом направлении изучения сознания на примере воображения как гипотетической функции сознания.
PENINGKATAN KEMANDIRIAN ANAK USIA DINI MELALUI MEDIA BIG BOOK PADA ANAK KELOMPOK B DI TK PUTRA PERTIWI XXI SUMBERARUM
Authors: Surti Surti , Dwitanto Octavian , Kusuma Wening Sekar
Published: July 2023

This study aims to increase children's independence and to determine children's independence in Group B TK Putra Pertiwi XXI Sumberarum after applying the big book media. The subjects of this study were the children of group B TK Putra Pertiwi XXI Sumberarum. This study uses Classroom Action Research (PTK) which is carried out in two cycles in each activity, with each activity per cycle consisting of planning, implementing, observing, and reflecting. The use of big book media adapted to existing themes as a source of learning is proven to be able to increase the independence of group B children in Putra Pertiwi XXI Sumberarum Kindergarten. The results in cycle I obtained a percentage of 70% and the increase in child independence in cycle II obtained results of 90%, with these results indicating that this research was successful or increased because it exceeded the research indicator targets that had been set, which was 80%. Big book media as a learning medium can be said to be successful in increasing children's independence if in this learning children are able to be independent in doing things on their own without the help of others.
HUBUNGAN ANTARA KECERDASAN EMOSIONAL TERHADAP KEMANDIRIAN PADA ANAK USIA DINI DALAM RENTAN USIA 4-5 TAHUN
Authors: Nurhikmah Maryam Nurhikmah , Yulianingsih Yuyun , Ratnasih Teti
Published: July 2023

Penelitian ini bertujuan untuk mengetahui hubungan kecerdasan emosional terhadap kemandirian anak usia dini, khususnya pada aspek perkembangan sosial emosional usia 4̄̄̄̄̄̄̄-5 tahun. Penelitian ini menggunakan metode dan pendekatan kuantitatif korelasional. Subjek dalam penelitian ini adalah Kelompok A di salah satu RA di Kota Bandung yang berjumlah 28 anak. Penelitian ini menggunakan sampel jenuh, yang artinya semua populasi dijadikan sampel. Teknik pengumpul data melalui lembar observasi. Hasil analisis data penelitian menggunakan perhitungan koefisien korelasi Spearman Rank memperoleh hasil hitung 0,91. Sedangkan hasil perhitungan uji signifikansi korelasi menggunakan t test diperoleh nilai thitung = 11,02 dan ttabel taraf signifikansi 5% dengan db = 26 sebesar 2,056. Maka thitung = 11,02  ttabel  = 2,056, dan dapat diinterpretasikan bahwa terdapat hubungan yang signifikan antara kecerdasan emosional dengan kemandirian anak usia dini. Selain itu, koefisien determinasi yang diperoleh sebesar 42%. Artinya, kecerdasan emosional memberikan kontribusi sebanyak 42% terhadap kemandirian anak usia dini di salah satu RA di Kota Bandung.
ST-elevation myocardial infarction, severe cardiogenic shock, and myocarditis secondary to leptospirosis: A rare case report
Authors: Sukmagautama Coana , Muhammad Faizal , Maharestri Ken Zuraida , Hanif Ihsan , Myrtha Risalina
Published: July 2023

Background: Leptospirosis is a bacterial infection that can lead to several organ dysfunctions. However, cardiac involvements in leptospirosis are uncommon findings. The unknown pathogenesis and association between leptospirosis and cardiac involvements can lead to a diagnostic challenge and case rarity. This study aims to report a diagnosis challenge through physical and laboratory examination of a patient with ST-elevation myocardial infarction (STEMI) and myocarditis without common leptospiral-associated organ dysfunction features. We also report the therapeutic strategies in this case, despite its clinical guideline limitation.
Case: A 35-year-old male patient came to the emergency department with flu-like symptoms. Twenty-four hours later, the patient showed acute angina, STEMI, and elevated high-sensitivity cardiac troponin followed by cardiogenic shock without significant modifiable and non-modifiable risk factors for heart diseases. The patient received fibrinolytic, supportive therapy and correction of hemodynamic derangement. We found thrombocytopenia on the second day. Surprisingly, the immunoserology showed positive anti-leptospira IgM and negative anti-dengue IgM and IgG. Further, there was echocardiography suspected myocarditis due to high echogenicity in the left ventricle's basal-apical lateral endocardium. Thus, we diagnosed this case as leptospirosis with cardiac involvement. Direct cardiac tissue damage due to systemic vasculitis, disseminated intravascular coagulation, and pro-inflammatory cytokine storm is believed to be pathomechanism in leptospirosis with cardiac involvement. After diagnosis establishment, his final therapies in the hospital were Aspirin, Atorvastatin, Clopidogrel, Spironolactone, Ramipril, Carvedilol, Omeprazole, Doxycycline, and Ceftriaxone. Subsequently, he was discharged from hospital and continued to receive cardiovascular medications, antibiotics, antiplatelet, potassium-sparing diuretics, and omeprazole.
Conclusion: This case highlights the importance of thorough clinical-laboratory evaluation in a patient with an atypical leptospiral presentation. Although  leptospirosis is not a common cause of heart diseases such as STEMI, cardiogenic shock, and myocarditis, we recommend supportive therapy and correction of hemodynamic derangement for leptospirosis with cardiac involvement, in addition to leptospiral antibiotic drug itself.
Prevention of Cardiovascular Disease in the Community Through Walking Intervention: Scoping Review
Authors: Widyawati Widyawati , Rahayuwati Laili , Mambang Sari Citra Windani , Irza Damar
Published: July 2023

Background: Cardiovascular disease is the number one killer in the world. The SDGs target reducing mortality through cost-effective prevention efforts. Physical activity, including walking, has been proven to prevent cardiovascular disease. Walking is an activity that is cheap, easy, simple, and does not need tools and skills, so it can be done in general by the community. However, the modern world makes people's walking activities low. There is a need to find evidence of walking interventions that can increase walking and prevent cardiovascular disease.
Purpose: This scoping review aims to identify literature focusing on walking interventions that increase footsteps and reduce disease risk to prevent cardiovascular disease.
Methods: Following the guidelines for the JBI scoping review methodology. Articles conducted searches on the Ebscho CINAHL, Academic, PubMed, and ProQuest databases from 2013 to 2021. The collected data were extracted in tabular and narrative form.
Results: Thirteen articles met the criteria involving 2,910 people from eight countries. Eleven studies used a randomized controlled trial, and two used a quasi-experimental design.
Conclusion: Walking interventions that support increased footsteps include: distance, duration per week (< 150 minutes or > 150 minutes), supervision, activities accompanied by socio-cultural activities, counselling, and motivation, in addition to the use of tools such as pedometers, accelerators, and smartwatch is used as a footstep monitor. Intervention in walking is beneficial in reducing cardiovascular diseases risk indicators such as blood pressure, BMI, blood glucose, cholesterol, and triglycerides.
Dialogue: Shorish and Nowviskie
Authors: Shorish Yasmeen , Nowviskie Bethany
Published: July 2023

This dialogue offers perspectives from two differently-positioned library leaders on their collaborative work to advance equity and racial justice in the context of a predominantly white academic library and educational technology organization. Topics covered include issues of scale and temporality in reckoning with structural racism; developing a workplace culture that supports growth and learning while mitigating harm; building and sustaining community both within and beyond formal institutions; developing personal and organizational accountability; and challenges in the use of data for assessing progress and working authentically toward change.   
Pre-print first published online 5/12/2022
Does It Matter
Authors: Ahmed Sumayya , Clemens Rachael , Patillo Ericka , Murillo Angela
Published: July 2023

The catalytic social justice events of the spring and summer of 2020 led to calls for a racial reckoning within society at large and also within the field of library and information science (LIS). This motivated us to capture the perceptions and voices of professionals across the field about changes they may have witnessed in their workplace, profession, and themselves. We consider the following questions: Have conversations, social spaces, teaching practices, policies, workplace dynamics, and demands, changed in response to the Black Lives Matter (BLM) protests, and if so, how? Have institutional changes perceived as responses to BLM protests been witnessed? What are the nuances behind such behavioral changes (e.g., opportunity, compulsion, peer pressure)? 
For this research, we used Critical Incident Technique (CIT) to explore how the 2020 BLM protests impacted the workplace environments of LIS faculty and professionals in libraries, archives, and museums (LAMs). A 27-question survey was administered via Qualtrics and participants were recruited using LAM professional listservs. A total of 645 participants completed the survey. This research provides the preliminary analysis and discussion of those results and provides insights to the impact of the 2020 social justice movements in LAMs.
By capturing voices of LAM professionals, we explore participants’ perceptions of the impact that BLM protests had on their institutions and/or professional associations and document a range of responses at both the individual and structural levels.
Pre-print first published online 9/30/2022
Socio-environmental problems of the development of water management in Dagestan
Authors: Eldarov Eldar Magomedovich
Published: July 2023

The article shows the most significant problems of functioning and development of the water economy of the Republic of Dagestan—the southernmost region of Russia. The results of a comprehensive analysis of the state of the waters of the Caspian Sea, the main pollutants of which are coastal cities and other settlements with their wastewater and other waste from human activities, are presented. Ecological problems of Dagestan rivers and reservoirs are considered. The necessity of restoring the natural state of the Terek River Delta, in particular the ecological rehabilitation of its estuarine streams and lakes, is emphasized. Special attention is paid to the task of stopping the uncontrolled economic development of reservoirs of mountain hydroelectric power plants—the main drinking water resources for the cities of Dagestan. The medical and hygienic condition of water supply sources is discussed with an emphasis on the serious problem of contamination of groundwater used for drinking purposes. The issues of water supply and sanitation (non-centralized, centralized, departmental and communal) are considered in detail. It is indicated that urban and district centralized water supply systems do not comply with sanitary and hygienic standards, and there is an extreme shortage of sewage treatment plants in almost all cities of the Republic. The progress of the implementation of a number of federal programs to improve the water supply systems of the population of the Republic is described.
Pharmacokinetics and plasma protein binding of a single dose of clodronate disodium are similar for juvenile sheep and horses
Authors: Vergara-Hernandez Fernando B. , Nielsen Brian D. , Kottwitz Jack J. , Panek Char L. , Robison Cara I. , Paris Brittany L. , Welsh Thomas H. , Bradbery Amanda N. , Leatherwood Jessica L. , Colbath Aimee C.
Published: July 2023

OBJECTIVE

To determine the single-dose pharmacokinetics of clodronate disodium (CLO) in juvenile sheep and the plasma protein binding (PPB) of CLO in juvenile sheep and horses.

ANIMALS

11 juvenile crossbred sheep (252 ± 6 days) for the pharmacokinetic study. Three juvenile crossbred sheep (281 ± 4 days) and 3 juvenile Quarter Horses (599 ± 25 days) for PPB analysis.

METHODS

CLO concentrations were determined using liquid chromatography-mass spectrometry. Pharmacokinetic parameters were calculated by noncompartmental analysis from plasma samples obtained at 0, 0.5, 1, 3, 6, 12, 24, 48, and 72 hours after CLO administered IM at 0.6 mg/kg. PPB was determined using equine and ovine plasma in a single-use rapid equilibrium dialysis system.

RESULTS

The mean and range for maximum plasma concentration (Cmax: 5,596; 2,396–8,613 ng/mL), time of maximal concentration (Tmax: 0.5; 0.5–1.0 h), and area under the curve (AUCall: 12,831; 7,590–17,593 h X ng/mL) were similar to those previously reported in horses. PPB in sheep and horses was moderate to high, with unbound fractions of 26.1 ± 5.1% in sheep and 18.7 ± 7.5% in horses, showing less than a 1.4-fold difference.

CLINICAL RELEVANCE

The pharmacokinetic parameters and PPB of CLO in juvenile sheep were similar to those previously reported in horses. The results suggest that juvenile sheep can be utilized as an animal model for studying the potential risks and/or benefits of bisphosphonate use in juvenile horses.
Hydrothermal synthesis and characterization of calcium phosphate-based coatings on AZ31 magnesium alloy
Authors: Horáková L. , Doskočil L. , Wasserbauer J. , Buchtík M.
Published: July 2023

This study aims to analyze the influence of process parameters used for hydrothermal synthesis of CaP coatings on their properties and to improve their corrosion resistance and biocompatibility compared to the substrat AZ31. The parameters monitored were deposition time, pH of the reaction mixture, and concentration of precursors in the reaction mixture. For the deposited CaP coatings on AZ31 magnesium alloy, the surface morphology and the number of structural defects were evaluated using scanning electron microscopy. Electrochemical corrosion properties were evaluated using polarization techniques in Hank’s solution. The results showed that the best properties were obtained for the sample prepared in a reaction mixture at 120 °C, pH 5 for a deposition time of 120 min, when the concentration of precursors in the reaction mixture was 0.30 mol/l Ca(NO3)2·4H2O and 0.28 mol/l NH4H2PO4. Under these conditions, the best electrochemical corrosion properties were achieved.
INVESTIGASI HUBUNGAN IRADIASI MATAHARI DENGAN THD PADA INVERTER PLTS UNIVERSITAS UDAYANA
Authors: Pandawani Anak Agung Istri , Indra Partha Cok. Gede , Sukerayasa I Wayan
Published: July 2023

Solar Power System as one of the uses of renewable energy whose use is very widespread and one of its implementations is on the roof of the DH Electrical Engineering Building of Udayana University. The increase in the use of solar power plants is followed by an increase in the use of switching equipment such as inverters that produce harmonic distortions and affect the power quality of the electrical system. This investigation aims to analyze the condition of THD in inverters and analyze factors related to THD in inverters, one of which is solar irradiation. THDi output inverter inverter PLTS Udayana University exceeds the permitted IEEE 519-2014 standard, which is a maximum of 5%. The relationship that occurs between irradiation and the inverter of Udayana University PLTS when connected to the load is inversely proportional so that when irradiation is high during the day, the THDi output of the inverter will be low and vice versa in the evening.
Introduction
Authors: Oziewicz Marek
Published: July 2023

In this Introduction to the inaugural issue of Climate Literacy in Education, the editorial collective describes the goals, scope, and vision for the journal. We outline the premises and commitments informing our work. We discuss what sets CLE apart from other journals (academic and professional). And we share a vision of CLE as a forum for everyone to share tips about building universal climate literacy with children’s literature and media.
CLICK Framework
Authors: Oziewicz Marek
Published: July 2023

This article outlines the Climate Literacy Capabilities and Knowledges (or CLICK) framework for climate literacy pedagogy. The framework includes four domains—Earth Care, Kinship Care, People Care, and Systems Care—and is modeled on the care-centric thinking central to the Indigenous Worldview and to other Earth stewardship efforts emerging today. The purpose of this article is to introduce CLICK as a conceptual tool to guide classroom practice.
PENENTUAN JENIS PELARUT TERBAIK TERHADAP KADAR EURYCUMANONE PADA EKSTRAKSI AKAR PASAK BUMI (EURYCOMA LONGIFOLIA JACK)
Authors: Malik Kirana , Setyaningrum Dyah , Wulansari Laela , Andayani Andayani , Shihran Laviany Putri , Fauziyyah Isra
Published: July 2023

Pasak bumi (Eurycoma longifolia Jack) adalah salah satu tanaman herbal dari negara-negara Asia Tenggara yaitu Indonesia, Malaysia, dan Vietnam.  Bagian tanaman yang memiliki khasiat adalah bagian daun, akar dan batang.  Berbagai macam senyawa kimia telah diisolasi dan dikarakterisasi dari Eurycoma longifolia, serta diketahui memiliki berbagai efek yang menguntungkan seperti male fertility enhancement effect, antimalarial effect, cytotoxic and anti-proliferative effect, antimicrobial effects, anti-inflammatory effects, anti-anxiolytic, anti diabetic, osteoporosis preventive effect, ameliorative effect, ergoganic effect, insecticidal effects, muscular effect, antiulcer effect dan anti-rheumatism effect.  Tanaman ini sangat potensial untuk digunakan dalam produk farmasi herbal.  Komposisi senyawa kimia dari tumbuhan adalah esensial untuk penentuan kualitas, keamanan dan efektifitas dari produk herbal. Penelitian ini dilakukan untuk mengetahui kandungan eurycomanone pada ekstrak akar pasak bumi, serta mengetahui pelarut terbaik dalam proses ekstraksi dari akar pasak bumi yang menghasilkan kadar eurycomanone tertinggi.  Metode pembuatan ekstrak dengan cara melakukan maserasi simplisia akar pasak bumi menggunakan pelarut etanol 30%, etanol 70%, etanol 96%, n-heksana, etilsetat dan air.  Tahap awal penelitian dimulai dengan melakukan uji fitokimia dan uji kadar air pada simplisa.  Selanjutnya pada masing-masing ekstrak dilakukan uji toksisitas terhadap larva udang serta penentuan kadar eurycomanone dengan High-performance liquid chromatography (HPLC).  Hasil rendemen ekstrak pasak bumi tertinggi terdapat pada ekstrak dengan menggunakan pelarut etanol 70% sebesar 3.41 g.  Hasil pengujian fitokimia simplisia pasak bumi mengandung flavonoid dan saponin.  Toksisitas tertinggi terdapat pada ekstrak dengan menggunakan pelarut etilasetat dengan nilai LC50 sebesar 201.28 ppm.  Ekstrak pasak bumi dengan pelarut etanol 70% memiliki kadar eurycomanone tertinggi yaitu 53.42 mg/g.
RIGLESS WELL INTERVENTION AND SAND CONSOLIDATION CHEMICAL APPLICATION TO SOLVE SAND PROBLEM OF ABC-2 WELL IN X FIELD
Authors: Utama Yeriandi , Mardiana Dwi Atty , Nugrahanti Asri
Published: July 2023

The decline in well production due to sand problems is the biggest challenge in a field that has been producing for a long time, especially in mature fields. In addition, and problems are also able to damage both the downhole and surface equipment of a well. Creating the right job design for sand cleanout and sand control is absolutely necessary to solve this problem. Rig less well intervention with coiled tubing is used to optimize this process. The sand cleanout job design is created using Insite for Well Intervention (IWI) software to create the right job design. In addition, a sand control method with sand consolidation chemicals will be applied to prevent the recurrence of sand problems after the well has been cleaned. The findings of the study indicate that the proper job design is able to clean the sand to target depth and restore the production of the ABC-2 wells to its pre-sand problem level. All factors, including sieve analysis, well data, coiled tubing data, and sand consolidation chemical, are taken into consideration during job design. Therefore, the sand issue in another mature well at the X field can be solved using this approach
NEUROTIC DISTRESS TOKOH NARUSE JUN DALAM ANIME KOKORO GA SAKEBITAGATTERUNDA KARYA MARI OKADA DENGAN PENDEKATAN PSIKOANALISIS SOSIAL KAREN HORNEY
Authors: Azhari Deasy Bintang , Listyaningsih
Published: July 2023

Penelitian ini membahas neurotic distress pada tokoh Naruse Jun dalam anime Kokoro Ga Sakebitagatterunda dan merumuskan faktor penyebab dan cara mengatasi neurotic distres dengan pendekatan teori psikoanalisis sosial milik Karen Horney. Teknik pengumpulan data menggunakan teknik dokumentasi dan dengan teknik analisis deskriptif. Kesimpulan dari penelitian ini adalah penyebab  awal dari neurotic distres yaitu kecemasan dasar dan permusuhan dasar oleh orang tuanya sendiri. Selain itu terdapat konflik yaitu konflik intrapsikis yang terdapat diri rendah yang berasal dari evaluasi bersifat negatif dari orang tuanya dan diri ideal yang Naruse ciptakan berbentuk khayalan dan keyakinan yang membuatnya menjadi tertutup dan tidak berbicara. Dalam konflik interpersonal terdapat kebutuhan kasih sayang dan penerimaan, kebutuhan partner, membatasi hidup pada ruang lingkup yang sempit, pengakuan sosisal dan mencukupi diri. Cara mengatasi neurotic distress yang dialami Naruse yaitu dengan cara memperbaiki dua konflik tersebut. Pada konflik Interpersonal Naruse mempunyai kecenderungan mendekat, cara ini hampir berhasil dalam membantu mengungkapkan apa yang ingin diutarakan, namun tidak saat mendengar Sakagami tidak memiliki rasa yang sama. Pada konflik Intrapsikis dengan melalui penyadaran diri yang dilakukan Sakagami dengan mengubah benci diri menjadi menerima diri, memberhentikan fantasi yang akhirnya Naruse dapat berdamai dengan masa lalunya.

Kata kunci: Anime; neurotic; psikoalisis sosial
Housemaid-Madam Relations in Black Households: Imagining Woman-to-Woman Exploitation in Two Zimbabwean Short Stories
Authors: Mangena Tendai
Published: July 2023

Domestic work is, in most cultures of the world, still considered to be the preserve of women. This is the case especially in the conservative patriarchal cultures in Zimbabwe where most maids in black households are still women. I analyse two short stories written by Zimbabwean writers, Julius Chingono’s “Maria’s Interview” and Petina Gappah’s “The Maid from Lalapanzi,” to explore the precarity of housemaids in black households. The madams are presented as having the financial wherewithal to hire maids, while housemaids are uneducated, poor and unmarried women and girls. Housemaids’ roles at their workplaces are depicted as ambiguous. They do the essential house chores yet are treated differently on account of being maids. From this ambiguity, the texts allow the reader to discern the maid’s exploitation epitomised by poor remuneration and general ill-treatment by the madams. In this article, I am interested in how Chingono and Gappah draw the reader’s attention to the many ways in which the relationship between madam and maid is an exemplar of black woman-to-woman exploitation.
Mountain flowers awe the eye and puzzle the botanist
Authors: Liu Rong
Published: July 2023

Usually, we identify plants by their showy and delicate flowers. Because flowers are selected to be more attractive compared with leaves, stems, or the hidden roots for most species. However, sometimes, when flowers from different but related species are similar, even the botanists might feel confused and misidentify them, which might lead to mistakes. So how can we identify them correctly?
The human reference genome is finally complete
Authors: Soto Daniela C. , Kirsche Melanie , Yan Stephanie M. , Zarate Samantha
Published: July 2023

Researchers rely on the human reference genome as a baseline to identify genetic differences between individuals, which are crucial for understanding human physiology, disease, and evolution. In this study, we focused on the implications of the first-ever complete human reference genome, which improves the identification of genetic variation and ushers in the beginning of a new era in genetics.
Halo Nevi After Covid-19 Vaccination: Molecular Mimicry Attributed Cutaneous Side-Effect?
Authors: Owens Kelly , Kwock Jeffery T. , Nicholas Matilda W.
Published: July 2023

Covid-19 vaccination is a crucial component of the public health response to reduce the spread of Covid-19. Although well-tolerated, Covid-19 vaccination is associated with several cutaneous adverse reactions. Here, we document a case of a young man who developed numerous halo nevi at sites of pre-existing nevi following Covid-19 vaccination. Our patient is a 21-year-old male who presented to clinic after noticing a recent change in his moles. Three months after receiving the Johnson & Johnson (J&J) Covid-19 vaccine, the patient reported that he developed a ring of “vitiligo” surrounding each of his existing moles. He also received the Moderna Covid-19 booster 8 months after receiving the J&J vaccine and contracted Covid-19 two months later, with no additional change in his moles. The patient was otherwise well with no past medical or family medical history of skin cancer. On examination, the patient was found to have numerous halo nevi that had developed at sites of pre-existing nevi and were distributed over his face, neck, trunk, and extremities. Examination of his scalp revealed patches of white hair, underneath which were additional halo nevi. The development of vitiligo in the setting of Covid-19 vaccination is thought to be related to the activation of autoimmunity. Autoimmunity secondary to Covid-19 vaccination may be the cause of this patient’s halo nevi, given the patient’s age and absence of any systemic symptoms.
Patch-Type Granuloma Annulare with Clinical and Histological Features of Morphea: A True Overlap?
Authors: Reeves Carlie , Falcone Lauryn , Beatty Collen J , Kazlouskaya Viktoryia , English III Joseph
Published: July 2023

A 67-year-old woman was evaluated for a worsening asymptomatic rash located on her torso, back, and legs. She denied any chills or fevers, and reported feeling otherwise well. Clinically, large brownish, slightly atrophic plaques were seen on the torso suggestive of either morphea or a granulomatous condition. Histopathologic examination revealed an increase in interstitial histiocytes infiltrating between altered collagen fibers, palisaded granulomas with increased mucin, suggestive of granuloma annulare (GA), as well as dermal sclerosis, perineural infiltrates with plasma cells and diminished CD34 counts, that are more typical for localized scleroderma/morphea. Morphea and patch-type GA may be indistinguishable clinically and share some histopathological features. This case demonstrates similarities between these conditions and features of both conditions in the same patient.