bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplemental Figure Legends from Depleting Tumor-NQO1 Potentiates Anoikis and Inhibits Growth of NSCLC
Authors: Madajewski Brian , Boatman Michael A. , Chakrabarti Gaurab , Boothman David A. , Bey Erik A.
Published: April 2023

Supplemental Figure Legends 1-14
Video S1 from Dual Targeting of Mesenchymal and Amoeboid Motility Hinders Metastatic Behavior
Authors: Jones Brandon C. , Kelley Laura C. , Loskutov Yuriy V. , Marinak Kristina M. , Kozyreva Varvara K. , Smolkin Matthew B. , Pugacheva Elena N.
Published: April 2023

Ibidi chemotactic invasion of MDA-MB-231 cells with NEDD9 depletion and ROCK inhibition
Data Supplement from Glucose-6–phosphatase Is a Key Metabolic Regulator of Glioblastoma Invasion
Authors: Abbadi Sara , Rodarte Julio J. , Abutaleb Ameer , Lavell Emily , Smith Chris L. , Ruff William , Schiller Jennifer , Olivi Alessandro , Levchenko Andre , Guerrero-Cazares Hugo , Quinones-Hinojosa Alfredo
Published: April 2023

Supplementary Movie S2, related to Supplementary Figure 3: G6PC is required in brain tumor initiating cells (BTICs) to regain their aggressive migratory behavior.
Supplementary Figures 2 - 3 from Dual Promoter Usage as Regulatory Mechanism of let-7c Expression in Leukemic and Solid Tumors
Authors: Pelosi Andrea , Careccia Silvia , Sagrestani Giulia , Nanni Simona , Manni Isabella , Schinzari Valeria , Martens Joost H.A. , Farsetti Antonella , Stunnenberg Hendrik G. , Gentileschi Maria Pia , Del Bufalo Donatella , De Maria Ruggero , Piaggio Giulia , Rizzo Maria Giulia
Published: April 2023

PDF file - 725KB, S2. Expression of the primary transcript of miR-99a and miR-125b in cell lines from different solid tumors. S3. UCSC track.
Fig S2 from Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155
Authors: Nyquist Michael D. , Corella Alexandra , Burns John , Coleman Ilsa , Gao Shuai , Tharakan Robin , Riggan Luke , Cai Changmeng , Corey Eva , Nelson Peter S. , Mostaghel Elahe A.
Published: April 2023

Fig S2. SLC35F2 Expression Determines Sensitivity to YM155
Supplemental Material and Methods from A New Role for ERα: Silencing via DNA Methylation of Basal, Stem Cell, and EMT Genes
Authors: Ariazi Eric A. , Taylor John C. , Black Michael A. , Nicolas Emmanuelle , Slifker Michael J. , Azzam Diana J. , Boyd Jeff
Published: April 2023

Supplemental Material and Methods
Supplemental Excel File 9 from A New Role for ERα: Silencing via DNA Methylation of Basal, Stem Cell, and EMT Genes
Authors: Ariazi Eric A. , Taylor John C. , Black Michael A. , Nicolas Emmanuelle , Slifker Michael J. , Azzam Diana J. , Boyd Jeff
Published: April 2023

Supplemental Excel File 9 - Candidate ERalpha DNA methylation targets
Supplementary Figures from Nuclear Localized LSR: A Novel Regulator of Breast Cancer Behavior and Tumorigenesis
Authors: Reaves Denise K. , Hoadley Katherine A. , Fagan-Solis Katerina D. , Jima Dereje D. , Bereman Michael , Thorpe Lynnelle , Hicks Jyla , McDonald David , Troester Melissa A. , Perou Charles M. , Fleming Jodie M.
Published: April 2023

S1. QPCR analysis of luminal progenitor and cancer stem cell genes. Primers were designed against the indicated genes. S2. Representative Z-stack projections of MCF7 breast cancer and MCF10AI breast epithelial cells generated from deconvolved slices using the maximum intensity criteria. S3. Ingenuity Pathway Analysis identification of the top biological functions and disorders associated with LSR target genes. S4. Top network generated via Path Designer of Ingenuity Pathway Analysis with LSR target genes. S5. ChIP-QPCR analysis of LSR target genes. S6. LSR expression in breast tumors stratified by menopause status. S7. Analysis of LSR expression in breast tumors. S8. Integrative Genomics Viewer snapshot image of RNA-seq data from MCF7, SUM149, SUM!59 and MDA-MB231 breast cancer cell lines. S9. Evolutionary conservation of LSR. S10. Predicted phosphorylation sites of full-length LSR. S11. Subcellular localization of LSR protein upon treatment with posttranslation modification pharmacologicals. S12. Localization of LSR binding sites on chromosomes.
Supplemental Excel File 5 from A New Role for ERα: Silencing via DNA Methylation of Basal, Stem Cell, and EMT Genes
Authors: Ariazi Eric A. , Taylor John C. , Black Michael A. , Nicolas Emmanuelle , Slifker Michael J. , Azzam Diana J. , Boyd Jeff
Published: April 2023

Supplemental Excel File 5 - Enrichment analysis of 153 Down-regulated Antihormone-resistance Genes.
S3. Accumulation of p-CREB in MCF-7 and TamR cells from IGF-1 Receptor Modulates FoxO1-Mediated Tamoxifen Response in Breast Cancer Cells
Authors: Vaziri-Gohar Ali , Zheng Yan , Houston Kevin D.
Published: April 2023

GPER1 and CREB expression and accumulation of p-CREB (S133) in MCF-7 and TamR cells. B, Accumulation of p-CREB (S133) after 2h Tam treatment in MCF-7 and TamR cells. * = p < 0.05 and results are average or representative of three independent experiments. Error bars are SEM.
Supplemental Excel File 10 from A New Role for ERα: Silencing via DNA Methylation of Basal, Stem Cell, and EMT Genes
Authors: Ariazi Eric A. , Taylor John C. , Black Michael A. , Nicolas Emmanuelle , Slifker Michael J. , Azzam Diana J. , Boyd Jeff
Published: April 2023

Supplemental Excel File 10 - Enrichment Analysis of 39 candidate ERalpha methylation targets
Data Supplement from PTEN Deficiency Mediates a Reciprocal Response to IGFI and mTOR Inhibition
Authors: Patel Mukund , Gomez Nicholas C. , McFadden Andrew W. , Moats-Staats Billie M. , Wu Sam , Rojas Andres , Sapp Travis , Simon Jeremy M. , Smith Scott V. , Kaiser-Rogers Kathleen , Davis Ian J.
Published: April 2023

Sup. Figure 1. MHH-ES-1 and RD-ES are triploid for chromosome 10. Sup. Figure 2. PTEN copy number variation in primary Ewing sarcoma. Sup. Figure 3. PTEN immunofluoresence is concordant with immunoblotting. Sup Figure 4. Immunofluoresence and immunohistochemical staining are highly concordant. Sup. Figure 5. Quantification of Cytoplasmic PTEN. Sup. Figure 6. IGF-1 sensitivity is not influence by the presence of PTEN. Sup. Figure 7. Expression of PTEN increases cleaved PARP. Sup. Figure 8. PTEN expression reduces the autophagy-mediated viability effects of temsirolimus.
Data Supplement from SMAD4 Suppresses AURKA-Induced Metastatic Phenotypes via Degradation of AURKA in a TGFβ-Independent Manner
Authors: Jia Lina , Lee Hun Seok , Wu Chun Fu , Kundu Juthika , Park Sang Gyu , Kim Ryong Nam , Wang Li-Hui , Erkin Özgür Cem , Choi Jong-Sun , Chae Seoung Wan , Yang Ho Bin , Choi Yoon-La , Shin Young Kee
Published: April 2023

Supplementary Figure 1B . AGS, SW480, and HeLa cells were pretreated with control siRNA (lane 1 and 2) or AURKA siRNA (10 nM, lane 3 and 4) for 48 h, and transfected with the plasmid encoding 6Myc-SMAD4 or empty vector. Cells were collected 24 h after transfection and subjected to cell migration and invasion assay (n=3). Data were presented as means {plus minus}SD obtained from three independent experiments (*P<0.05, Ã¢?Â P<0.01, Ã¢?Â¡P<0.001, compared to the control group).
Supplementary Methods from Loss of Keratinocytic RXRα Combined with Activated CDK4 or Oncogenic NRAS Generates UVB-Induced Melanomas via Loss of p53 and PTEN in the Tumor Microenvironment
Authors: Coleman Daniel J. , Chagani Sharmeen , Hyter Stephen , Sherman Anna M. , Löhr Christiane V. , Liang Xiaobo , Ganguli-Indra Gitali , Indra Arup K.
Published: April 2023

Supplementary methods
Supplementary Figure 8 from Loss of Keratinocytic RXRα Combined with Activated CDK4 or Oncogenic NRAS Generates UVB-Induced Melanomas via Loss of p53 and PTEN in the Tumor Microenvironment
Authors: Coleman Daniel J. , Chagani Sharmeen , Hyter Stephen , Sherman Anna M. , Löhr Christiane V. , Liang Xiaobo , Ganguli-Indra Gitali , Indra Arup K.
Published: April 2023

Supplementary Figure S8: Chronically UVB-irradiated tumor-adjacent normal skin from Tyr-NRASQBtK or Cdk4R24c mice with epidermis-specific knockout of Rxra show modest increase in CDK4 expression; downregulation of phosphorylated ERK, as well as increased E2F1 expression specifically in Rxraep-/- 1 Cdk4R24c mice. (A-D) Modest increase of CDK4 expression in both epidermis and dermis of Rxraep-/- I Tyr- NRASQ61K and Rxraep-/- 1 Cdk4R24c mice as compared to RxraL2/L2 controls, as determined by immunohistochemistry (5 IJm bleached paraffin sections). E=Epidermis, D= Dermis. Scale bars= 50 IJm. # = no statistical significance , *= p s 0.05, *** = p s 0.001 (E, F) Down regulation in phosphorylated ERK in tumor-adjacent normal skin of Rxraep-/- 1 Tyr-NRASQotK and Rxraep-/- 1 Cdk4R24cmice as compared to RxraL2/L2 controls; as shown by Western Blot (Two biological replicates for each group are shown). (G, H) Analysis of E2F1 protein levels in tumor-adjacent normal skin of Rxraep-/- 1 Tyr-NRASQotK and Rxraep-/- I Cdk4R24c mice as compared to RxraL2/L2 controls; as shown by Western Blot (Two biological replicates for each group are shown). No difference was observed in the Tyr-NRASQotK group, while increased E2F1 levels were observed in Rxraep-/- 1 Cdk4R'
Supplementary Figure 7 from Loss of Keratinocytic RXRα Combined with Activated CDK4 or Oncogenic NRAS Generates UVB-Induced Melanomas via Loss of p53 and PTEN in the Tumor Microenvironment
Authors: Coleman Daniel J. , Chagani Sharmeen , Hyter Stephen , Sherman Anna M. , Löhr Christiane V. , Liang Xiaobo , Ganguli-Indra Gitali , Indra Arup K.
Published: April 2023

Supplementary Figure S7: Heat Map and Clustergram of dysregulated genes in melanocytic lesions from Rxraep-/- 1 Cdk4R>
Supplementary Figure 4 from Loss of Keratinocytic RXRα Combined with Activated CDK4 or Oncogenic NRAS Generates UVB-Induced Melanomas via Loss of p53 and PTEN in the Tumor Microenvironment
Authors: Coleman Daniel J. , Chagani Sharmeen , Hyter Stephen , Sherman Anna M. , Löhr Christiane V. , Liang Xiaobo , Ganguli-Indra Gitali , Indra Arup K.
Published: April 2023

Supplementary Figure S4: An increase in infiltrating macrophages is observed in melanocytic lesions from Cdk4R24cmice with epidermal-specific knockout of Rxra, but not in Rxraep-/- Tyr-NRASQBtK mice. No change in infiltrating CD4+ T-cells observed in melanocytic lesions from either Cdk4R24c or Tyr-NRASQ61K mice with epidermal-specific knockout of Rxra. (A, B) No change in infiltrating macrophages, as determined by fluorescent immunohistochemistry (I HC) of of 5 J.lm paraffin sections (MAC1 antigen), was observed in Rxraep-/- 1 Tyr-NRAS061K mice as compared to RxraL2/L2 controls. (C, D) An increase in infiltrating macrophages was observed in Rxraep-/- 1 Cdk4R24c mice as compared to RxraL2/L2 controls. (E-H) No change in infiltrating CD4+ T-cells as determined by fluorescent IHC was observed in Rxraep-/- Tyr-NRAS061K or Rxraep-/- Cdk4R24c mice as compared to RxraL 21L2 controls. Scale bars= 50 J.lm. ** = p :5 0.01
Supplementary Data Table S.3 from Pathology-Driven Comprehensive Proteomic Profiling of the Prostate Cancer Tumor Microenvironment
Authors: Staunton Lisa , Tonry Claire , Lis Rosina , Espina Virginia , Liotta Lance , Inzitari Rosanna , Bowden Michaela , Fabre Aurelie , O'Leary John , Finn Stephen P. , Loda Massimo , Pennington Stephen R.
Published: April 2023

Incidence of biochemical recurrence in 133 patients from the validation cohort
Supplementary Figure 2 from Loss of Keratinocytic RXRα Combined with Activated CDK4 or Oncogenic NRAS Generates UVB-Induced Melanomas via Loss of p53 and PTEN in the Tumor Microenvironment
Authors: Coleman Daniel J. , Chagani Sharmeen , Hyter Stephen , Sherman Anna M. , Löhr Christiane V. , Liang Xiaobo , Ganguli-Indra Gitali , Indra Arup K.
Published: April 2023

Supplementary Figure S2: Chronic-UVB treated and parallel non-treated controls used in this study. (A,B) H&E staining of non-UVB treated skin from parallel age-matched mice (A) and TAN skin from chronic-UVB treated mice (B). In all groups, TAN skin has similar morphology to non-UVB treated skin, except for increased epidermal thickening; and dermal pigmentation which is enhanced further in the RXRaep-/- mice. Mice carrying Cdk4R24c in all groups show sebaceous gland hyperplasia within hair follicles (yellow boxes). E=Epidermis, D=Dermis, scale bar =100 IJm. (C) Epidermis measurements taken from H&E stained samples. In non-UVB treated mice, Tyr-NRAS0 61K or Cdk4R24c combined with Rxraep-/- mutation exhibited slightly thicker epidermis than RxraL2/L2 counterparts [7]. This is attenuated by chronic-UVB treatment, which results in a similarly thickened epidermis across all groups. ** = p<0.1 , ***= p<.01 , ***=p<.0001. (D) RxraL2/L2 and Rxraep-/- mice lacking Tyr-NRAS061K or Cdk4R24c mutations do not develop melanocytic tumors in response to chronic-UVB treatment. (E) Non-UVB treated RxraL21L2 and RXRaep-/- mice carrying Tyr-NRAS061K or Cdk4R24c do not develop melanocytic tumors. RXRaep-/- Tyr-NRAS061K and RXRaep-/- Cdk4R24c do develop small melanocytic nevi which do not increase in size.
Supplementary Figure 1 from Loss of Keratinocytic RXRα Combined with Activated CDK4 or Oncogenic NRAS Generates UVB-Induced Melanomas via Loss of p53 and PTEN in the Tumor Microenvironment
Authors: Coleman Daniel J. , Chagani Sharmeen , Hyter Stephen , Sherman Anna M. , Löhr Christiane V. , Liang Xiaobo , Ganguli-Indra Gitali , Indra Arup K.
Published: April 2023

Supplementary Figure S1: Breeding/Genotyping of mouse lines used in this study. (A, B) Breeding crossings used. K14-Cre'g/O I RxraL2/L2 is also known as RXRaep-/-. (C) Semi-quantitative PCR was performed on biopsies containing both epidermal and non-epidermal tissue; to confirm genotypes with regard to presence/absence of K14-Cre recombinase (top), epidermis-specific ere-mediated excision of Rxra exon 4 (middle), and the mutant Cdk4R24c allele (bottom). Presence of K14-Cre recombinase is indicated by a single 349 bp band; animals negative for K14-Cre show no amplification. In K14-Cre positive animals, ere-mediated epidermis-specific excision of Rxra is indicated by a 110 bp (L-) band, while a 203 bp (L2) band is also amplified due to presence of non-epidermal tissue in the biopsy in which excision did not occur. Animals negative for K14-Cre show only the 203 bp (L2) band for Rxra, as no excision occurred in any tissue. Animals homozygous for the mutant Cdk4R24c allele show a single band at 530 bp, while animals homozygous for the WT Cdk4 allele show a single band at 440 bp. Primers used are detailed in the Supplementary Table S2. (D) Tyr-NRAS061K genotype is determined phenotypically 10-12 days postnatal by presence/absence of dark pigmentation of the foot pads.
Supplemental figures from Cyclin A2 and CDK2 as Novel Targets of Aspirin and Salicylic Acid: A Potential Role in Cancer Prevention
Authors: Dachineni Rakesh , Ai Guoqiang , Kumar D. Ramesh , Sadhu Satya S. , Tummala Hemachand , Bhat G. Jayarama
Published: April 2023

Supplemental Figures 1-6
Supplemental Figure 1 from Novel Insights into Gastric Cancer: Methylation of R-spondins and Regulation of LGR5 by SP1
Authors: Wilhelm Franziska , Simon Eva , Böger Christine , Behrens Hans-Michael , Krüger Sandra , Röcken Christoph
Published: April 2023

Primer sequences used.
Supplemental Figure S6 from MYC Mediates mRNA Cap Methylation of Canonical Wnt/β-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase
Authors: Posternak Valeriya , Ung Matthew H. , Cheng Chao , Cole Michael D.
Published: April 2023

Immunoprecipitation of XPB, MYC, TIP60, CDK7, or MRG15 from IMEC:MYC cells. Co-immunoprecipitated proteins detected using Western blot.
Supplemental Figure S5 from MYC Mediates mRNA Cap Methylation of Canonical Wnt/β-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase
Authors: Posternak Valeriya , Ung Matthew H. , Cheng Chao , Cole Michael D.
Published: April 2023

TFIIH, specifically CDK7, promotes mRNA cap methylation of canonical Wnt/beta-catenin signaling pathway transcripts.
Supplemental Figure 5 from AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27
Authors: Kopsiaftis Stavros , Sullivan Katie L. , Garg Isha , Taylor John A. , Claffey Kevin P.
Published: April 2023

AMPKï�¡2 knockdown reduces p27 through a SKP2-mediated mechanism and results in a proliferative advantage.
Data Supplement from Extrinsic Apoptosis Is Impeded by Direct Binding of the APL Fusion Protein NPM-RAR to TRADD
Authors: Chattopadhyay Anuja , Hood Brian L. , Conrads Thomas P. , Redner Robert L.
Published: April 2023

Supplementary Figure 1. TNF-alpha induced apoptosis. Cells were treated with 2.5 ng/ml TNF-alpha and 250 ng/ml CHX, ethanol fixed, and stained with PI. The percentage of cells containing sub-G/G1 DNA content was assessed by flow cytometry at time 0, 60, 90, and 120 minutes after exposure to TNF-alpha.
Supplemental Figure 3 from AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27
Authors: Kopsiaftis Stavros , Sullivan Katie L. , Garg Isha , Taylor John A. , Claffey Kevin P.
Published: April 2023

AMPKï�¡2 knockdown in bladder cancer cells reduces p27 protein A-B.
Supplementary Table S1 from VEGFR-1 Pseudogene Expression and Regulatory Function in Human Colorectal Cancer Cells
Authors: Ye Xiangcang , Fan Fan , Bhattacharya Rajat , Bellister Seth , Boulbes Delphine R. , Wang Rui , Xia Ling , Ivan Cristina , Zheng Xiaofeng , Calin George A. , Wang Jing , Lu Xiongbin , Ellis Lee M.
Published: April 2023

Supplementary Table S1. Oligonucleotide Primers, Probes, and siRNAs Used in the Study
Supplementary Figures S1-S6 from VEGFR-1 Pseudogene Expression and Regulatory Function in Human Colorectal Cancer Cells
Authors: Ye Xiangcang , Fan Fan , Bhattacharya Rajat , Bellister Seth , Boulbes Delphine R. , Wang Rui , Xia Ling , Ivan Cristina , Zheng Xiaofeng , Calin George A. , Wang Jing , Lu Xiongbin , Ellis Lee M.
Published: April 2023

Supplementary Figures S1-S6. Supplementary Figure S1. Expression of FLT1P1 in human colorectal tumor specimens. Supplementary Figure S2. Bidirectional transcription of FLT1P1 in human CRC cell lines and colorectal tumor specimens. Supplementary Figure S3. Validation of FLT1P1 RNAi in CRC cells. Supplementary Figure S4. ShFLT1P1-3 has a similar function as shFLT1P1-1 in HCP1 cells. Supplementary Figure S5. Knockdown of both FLT1P1 transcripts by dual shRNAs had an inhibitory effect on VEGFR1 and VEGF-A expression in HCP1 cells. Supplementary Figure S6. Sustained RNAi by shFLT1P1-1 inhibited HCP1 cell proliferation.
Supplemental Figures (Fig. S1-S4) from miR-202 Diminishes TGFβ Receptors and Attenuates TGFβ1-Induced EMT in Pancreatic Cancer
Authors: Mody Hardik R. , Hung Sau Wai , Pathak Rakesh K. , Griffin Jazmine , Cruz-Monserrate Zobeida , Govindarajan Rajgopal
Published: April 2023

S1. DZNep decreases TGFBR1 and TGFBR2 levels and induces miR-202-5p expression in additional cancer cell lines. S2. Relative expression levels of miR-202-5p, TGFBR1, and TGFBR2 in a panel of pancreatic cancer cell lines. S3. MiR-202-5p targets TGFBR1 in the pancreatic cancer cell line, MIA PaCa-2. A-B. S4. AntimiR-202-5p (antagomiR of miR-202-5p) did not affect the expression levels of other miRNAs (miR-663a and miR-4787-5p).
Supplemental Figures S1-S9 from INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC
Authors: Reed Darien E. , Shokat Kevan M.
Published: April 2023

S1. PI3K pathway and mutations in cancer. S2. PI3K inhibitor chemical structures. S3. Effect of INPP4B siRNA on Akt signaling. S4. Effect of INPP4B siRNA on PI3K inhibitor GI50s. S5. Effect of CRISPR-mediated knockout of INPP4B in HCC70 cells on Akt signaling in response to PI3K-αI. S6. Effect of CRISPR-mediated knockout of INPP4B in HCC70 cells on PI3K inhibitor GI50s. S7. Effect of CRISPR-mediated knockout of INPP4B in BT549 cells on Akt signaling. S8. Effect of CRISPR-mediated knockdown of INPP4B in BT549 cells on PI3K inhibitor GI50s. S9. Effect of the pan PI3Ki on in vitro PI3K activity.
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Authors: Wei Darmood , Goldfarb Dennis , Song Shujie , Cannon Courtney , Yan Feng , Sakellariou-Thompson Donastas , Emanuele Michael , Major Michael B. , Weissman Bernard E. , Kuwahara Yasumichi
Published: April 2023

Supplementary Figure S1. This supplementary figure shows that SNF5 KD in normal human fibroblasts does not alter mRNA levels of SWI/SNF components.
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Authors: Wei Darmood , Goldfarb Dennis , Song Shujie , Cannon Courtney , Yan Feng , Sakellariou-Thompson Donastas , Emanuele Michael , Major Michael B. , Weissman Bernard E. , Kuwahara Yasumichi
Published: April 2023

Supplementary Table 1. A table of the antibodies and their sources used for these studies
Supplementary Figure 3 from ERβ Regulates NSCLC Phenotypes by Controlling Oncogenic RAS Signaling
Authors: Nikolos Fotis , Thomas Christoforos , Rajapaksa Gayani , Bado Igor , Gustafsson Jan-Åke
Published: April 2023

PDF file - 784K, S3. Expression of Cyclin D2 in NSCLC cells.
Supplementary Methods and Materials from Whole Transcriptome Sequencing Reveals Extensive Unspliced mRNA in Metastatic Castration-Resistant Prostate Cancer
Authors: Sowalsky Adam G. , Xia Zheng , Wang Liguo , Zhao Hao , Chen Shaoyong , Bubley Glenn J. , Balk Steven P. , Li Wei
Published: April 2023

Supplementary Methods and Materials
Supplementary Figure Legends from Whole Transcriptome Sequencing Reveals Extensive Unspliced mRNA in Metastatic Castration-Resistant Prostate Cancer
Authors: Sowalsky Adam G. , Xia Zheng , Wang Liguo , Zhao Hao , Chen Shaoyong , Bubley Glenn J. , Balk Steven P. , Li Wei
Published: April 2023

Supplementary Figure Legends
Supplementary Movie 1 from TRAP1 Regulates Proliferation, Mitochondrial Function, and Has Prognostic Significance in NSCLC
Authors: Agorreta Jackeline , Hu Jianting , Liu Dongxia , Delia Domenico , Turley Helen , Ferguson David JP. , Iborra Francisco , Pajares María J. , Larrayoz Marta , Zudaire Isabel , Pio Ruben , Montuenga Luis M. , Harris Adrian L. , Gatter Kevin , Pezzella Francesco
Published: April 2023

WMV - 9857K, Video of scr-siRNA treated A549 cell growth.
Supplementary Figure 7 from Whole Transcriptome Sequencing Reveals Extensive Unspliced mRNA in Metastatic Castration-Resistant Prostate Cancer
Authors: Sowalsky Adam G. , Xia Zheng , Wang Liguo , Zhao Hao , Chen Shaoyong , Bubley Glenn J. , Balk Steven P. , Li Wei
Published: April 2023

Positive correlation between intron and exon expression in CRPCsamples.
Supplementary Table 2 from Mutational Landscape of the Essential Autophagy Gene BECN1 in Human Cancers
Authors: Laddha Saurabh V. , Ganesan Shridar , Chan Chang S. , White Eileen
Published: April 2023

PDF file - 1442KB, Table S2. TCGA cancers with available somatic mutation data from whole genome or exome sequencing and the total number of mutations found for BECN1 and BRCA1.
Supplementary Figure 4 from P-Cadherin Promotes Ovarian Cancer Dissemination Through Tumor Cell Aggregation and Tumor–Peritoneum Interactions
Authors: Usui Akihiro , Ko Song Yi , Barengo Nicolas , Naora Honami
Published: April 2023

PDF file - 7573K, Supplemental Figure S4. Knockdown of P-cadherin does not affect cell proliferation or cell death in solid tumors.
Supplementary Figure 1 from P-Cadherin Promotes Ovarian Cancer Dissemination Through Tumor Cell Aggregation and Tumor–Peritoneum Interactions
Authors: Usui Akihiro , Ko Song Yi , Barengo Nicolas , Naora Honami
Published: April 2023

PDF file - 657K, Supplemental Figure S1. Effect of P-cadherin on expression of EMT-associated genes.
Supplementary figures 1 to 6 from Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation
Authors: Hassani Zahra , Saleh Ali , Turpault Soumaya , Khiati Salim , Morelle Willy , Vignon Jacques , Hugnot Jean-Philippe , Uro-Coste Emmanuelle , Legrand Philippe , Delaforge Marcel , Loiseau Séverine , Clarion Ludovic , Lecouvey Marc , Volle Jean-Noël , Virieux David , Pirat Jean-Luc , Duffau Hugues , Bakalara Norbert
Published: April 2023

Supplementary figures providing additionnal information concerning: - The cells glycome before and after PST3.1a treatment as measured by mass spectrometry (Supp. Figure 1) or Glycoprofile (Supp. Figure 2) - The absence of effect of PST3.1a on O-Glycosylation (Supp. Figure 3) - Western blot quantifications (Supp. Figure 4) - The inhibition of cell invasion in matrigel by PST3.1a (Supp. Figure 5) - The absence of cytotoxicity on non-proliferating PBMC cells (Supp. Figure 6).
Figure S1 from EWS/FLI is a Master Regulator of Metabolic Reprogramming in Ewing Sarcoma
Authors: Tanner Jason M. , Bensard Claire , Wei Peng , Krah Nathan M. , Schell John C. , Gardiner Jamie , Schiffman Joshua , Lessnick Stephen L. , Rutter Jared
Published: April 2023

Additional GSEA plots, Seahorse analysis data, and FPKM of hexokinase 1 from RNA-seq analysis.
Supplementary Tables from Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC
Authors: Güttlein Leandro N. , Benedetti Lorena G. , Fresno Cristóbal , Spallanzani Raúl G. , Mansilla Sabrina F. , Rotondaro Cecilia , Raffo Iraolagoitia Ximena L. , Salvatierra Edgardo , Bravo Alicia I. , Fernández Elmer A. , Gottifredi Vanesa , Zwirner Norberto W. , Llera Andrea S. , Podhajcer Osvaldo L.
Published: April 2023

This file contains Supplementary Tables S1-S12
Supplementary Figures from Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC
Authors: Güttlein Leandro N. , Benedetti Lorena G. , Fresno Cristóbal , Spallanzani Raúl G. , Mansilla Sabrina F. , Rotondaro Cecilia , Raffo Iraolagoitia Ximena L. , Salvatierra Edgardo , Bravo Alicia I. , Fernández Elmer A. , Gottifredi Vanesa , Zwirner Norberto W. , Llera Andrea S. , Podhajcer Osvaldo L.
Published: April 2023

Figure S1. Association between SPARC expression and distant metastasis free survival (RFS) in breast cancer patients with different PAM50 subtypes. Figure S2. Downregulation of SPARC expression in 4T1 and LM3 murine breast cancer cell lines. Figure S3. SPARC targeting inhibits primary tumor growth and lung metastasis establishment. Figure S4. SPARC-deficient cells exhibit a delay in cell cycle progression. Figure S5. Transcriptomic analysis of SPARC-deficient tumors revealed changes in cell-ECM interaction and immune response. Figure S6. Enforced expression of COX-2 in SPARC-deficient 4T1 cells partially restores cells capacity to grow as primary tumor. Figure S7. SPARC targeting impairs invasive capacity of breast cancer cells. Figure S8. Association between hS-PT and hS-ESM expression and distant metastasis free survival (RFS) in breast cancer patients with different PAM50 subtypes.
Supplementary Figure 3 from Active FOXO1 Is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming
Authors: Diep Caroline H. , Knutson Todd P. , Lange Carol A.
Published: April 2023

PR-A-induced cellular senescence is dependent on FOXO1 activity.
Supplemental Figure 3 from Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility
Authors: Clausen Thomas Mandel , Pereira Marina Ayres , Al Nakouzi Nader , Oo Htoo Zarni , Agerbæk Mette Ø , Lee Sherry , Ørum-Madsen Maj Sofie , Kristensen Anders Riis , El-Naggar Amal , Grandgenett Paul M. , Grem Jean L. , Hollingsworth Michael A. , Holst Peter J. , Theander Thor , Sorensen Poul H. , Daugaard Mads , Salanti Ali
Published: April 2023

Slope analysis of subcutaneous B16 tumor initiation
Supplemental Figure 2 from Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility
Authors: Clausen Thomas Mandel , Pereira Marina Ayres , Al Nakouzi Nader , Oo Htoo Zarni , Agerbæk Mette Ø , Lee Sherry , Ørum-Madsen Maj Sofie , Kristensen Anders Riis , El-Naggar Amal , Grandgenett Paul M. , Grem Jean L. , Hollingsworth Michael A. , Holst Peter J. , Theander Thor , Sorensen Poul H. , Daugaard Mads , Salanti Ali
Published: April 2023

CS and Integrin signaling
Data Supplement from ID1 Promotes Breast Cancer Metastasis by S100A9 Regulation
Authors: Gumireddy Kiranmai , Li Anping , Kossenkov Andrew V. , Cai Kathy Q. , Liu Qin , Yan Jinchun , Xu Hua , Showe Louise , Zhang Lin , Huang Qihong
Published: April 2023

Supplementary Figure 1. Expression of Id1 and Id2 was determined by qRT-PCR in MCF7 cells expressing a vector control, or Id1, or Id2. Supplemenatary Figure 2. Id1 expression in human primary breast cancer and metastatic samples, and MCF7 cells expressing a vector control or Id1 was determined by qRT-PCR (A). Immunoblot of Id1 expression in MCF7 cells expressing a vector control or Id1 (B). Supplementary Figure 3. Top gene candidates that are suppressed by Id1 but not by Id2 are listed. The fold change shows the expression fold decrease in MCF7 cells stably expressing Id1 versus control. Heatmap shows the expression of top ten genes across samples with blue shades indicating lower expression and red shades indicating higher expression of a gene in a sample. Supplementary Figure 4. Id1 suppresses S100A9 expression. (A) Quantitative RT-PCR of S100A9 expression in MCF7 cells transiently transfected with a vector control, or Id1, or Id2. (B) Immunoblots of S100A9 expression in MCF7 cells transiently transfected with a vector control, or Id1, or Id2. Supplementary Figure 5. S100A9 mediates the Id1 functions in migration and invasion. (A) S100A9 expression in MCF7 cells transiently transfected with a vector control, or Id1, or Id1 and S100A9. (B-C) MCF7 cells transiently transfected with a vector control, or Id1, or Id1 and S100A9 were subjected to migration assay (B) and invasion assay (C). Id1 expression in MCF7 cells increased cell migration and invasion. Expression of S100A9 cDNA reversed migratory and invasive phenotypes induced by Id1 expression (B and C). Supplementary Figure 6. Cell growth of MCF7 cells expressing a vector control, or Id1, or Id2, or Id1 and S100A9, or Id1 plus S100A9 and RhoC. Expression of Id1, or Id2, or S100A9 or RhoC in MCF7 cells did not affect cell growth.
Supplementary Materials and Methods from miR-19–Mediated Inhibition of Transglutaminase-2 Leads to Enhanced Invasion and Metastasis in Colorectal Cancer
Authors: Cellura D. , Pickard K. , Quaratino S. , Parker H. , Strefford J.C. , Thomas G.J. , Mitter R. , Mirnezami A.H. , Peake N.J.
Published: April 2023

Supplementary Materials and Methods
Supplementary Figure 1, Tables 1 - 2 from Prostate Cancer Genetic-susceptibility Locus on Chromosome 20q13 is Amplified and Coupled to Androgen Receptor-regulation in Metastatic Tumors
Authors: Labbé David P. , Nowak Dawid G. , Deblois Geneviève , Lessard Laurent , Giguère Vincent , Trotman Lloyd C. , Tremblay Michel L.
Published: April 2023

PDF file - 83K, Figure S1: Co-amplification of AR and CAR in metastatic samples. Supplementary Table 1: List of the different oligonucleotides used for the analysis of gene expression. Supplementary Table 2: List of the AR binding sites in LNCaP on the 20q chromosome.
Table S1 from miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4
Authors: Prossomariti Anna , Piazzi Giulia , D'Angelo Leonarda , Miccoli Sara , Turchetti Daniela , Alquati Chiara , Montagna Claudio , Bazzoli Franco , Ricciardiello Luigi
Published: April 2023

List of primary antibodies used for western blotting analysis.
Figure S7 from miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4
Authors: Prossomariti Anna , Piazzi Giulia , D'Angelo Leonarda , Miccoli Sara , Turchetti Daniela , Alquati Chiara , Montagna Claudio , Bazzoli Franco , Ricciardiello Luigi
Published: April 2023

Protein quantification of cleaved and total CASPASE-3 in DLD-1 and SW480 cells upon miR-155-5p induction.
Figure S6 from miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4
Authors: Prossomariti Anna , Piazzi Giulia , D'Angelo Leonarda , Miccoli Sara , Turchetti Daniela , Alquati Chiara , Montagna Claudio , Bazzoli Franco , Ricciardiello Luigi
Published: April 2023

Protein quantification of WNT signaling components in DLD-1 and SW480 cells upon WNT3A stimulation alone or in combination with miR-155-5p induction.
Supplementary Figures 8-9 from Olaparib, Monotherapy or with Ionizing Radiation, Exacerbates DNA Damage in Normal Tissues: Insights from a New p21 Reporter Mouse
Authors: McMahon Michael , Frangova Tania G. , Henderson Colin J. , Wolf C. Roland
Published: April 2023

Figure S8: Î’-gal staining is localized to the nucleus of cells. Figure S9: Kidney and liver function tests on plasma from cisplatin-treated reporter mice.
Figure S4 from miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4
Authors: Prossomariti Anna , Piazzi Giulia , D'Angelo Leonarda , Miccoli Sara , Turchetti Daniela , Alquati Chiara , Montagna Claudio , Bazzoli Franco , Ricciardiello Luigi
Published: April 2023

miR-155-5p binding to the TCF4 3'UTR.
Supplementary Figures 11-13 from Olaparib, Monotherapy or with Ionizing Radiation, Exacerbates DNA Damage in Normal Tissues: Insights from a New p21 Reporter Mouse
Authors: McMahon Michael , Frangova Tania G. , Henderson Colin J. , Wolf C. Roland
Published: April 2023

Figure S11: Bioluminescence from irradiated reporter mice. Figure S12: Visceral organ bioluminescence observed by invasive imaging. Figure S13: Pharmacokinetic parameters for olaparib in wild-type mice are linearly related to dose.
Supplementary Figures and tables from A Functional Screen Identifies miRs That Induce Radioresistance in Glioblastomas
Authors: Moskwa Patryk , Zinn Pascal O. , Choi Young Eun , Shukla Sachet A. , Fendler Wojciech , Chen Clark C. , Lu Jun , Golub Todd R. , Hjelmeland Anita , Chowdhury Dipanjan
Published: April 2023

S1A. List of miRNAs enriched independent of IR. S1B. Clonogenic survival assay was performed with 2 Gy IR in 12 different GBM lines. Bar graphs were generated with Mean {plus minus} S.D. of 3 independent experiments. S2A. IR sensitivity of LN229 with individual stable expression of miR-1, miR-125a, miR-150 and miR-425 was determined by clonogenic assay. Curves were generated with Mean {plus minus} S.D. of 3 independent experiments. For statistical analysis the areas under the curves were calculated by approximating them to trapezoids. Comparison was done with one-way ANOVA (p < 0.05) and Tukey's post hoc (p < 0.05) test. S2B. Expression of fused miR-1, miR-125a, miR-150 and miR-425 from pcDNA3.1 vector. S3. A) Illustration shows the construct of GFP-fused miRNA sponges. GFP is fused at the 3' end of 4 identical repeats of miRNA sponges in tandem. The sequence of each miRNA sponge is shown below. (B) Inhibition of GFP expression fused to miRNA sponges was tested by transfecting corresponding miRNA mimics. Comparison was done with one-way ANOVA (p < 0.05) and Tukey's post hoc (p < 0.05) test. S4A. Impact of individual miR-scr, miR-1, miR-125a, miR-150 and miR-425 and combined miR-4x' on apoptosis in LN229 cells. Cells were exposed to 10 Gy γ-IR and the activation of Caspase 3 and 7 was determined with Caspase-Glo 3/7 Assay System. Comparison was done with one-way ANOVA (p < 0.05) and Tukey's post hoc (p < 0.05) test. S4B. Phosphorylation of Chk1 S345 in LN229 cells transfected with indicated miRNA upon exposure to 10 Gy IR. The mean {plus minus} S.D. of 3 independent experiments is demonstrated. Comparison was done with one-way ANOVA (p < 0.05) and Tukey's post hoc (p <0.05) test. S5. Expression of PAI-1 was examined upon stimulation with TGF-β with or without TGF-β inhibitor in indicated GBM cell lines. Bar graphs were generated with Mean {plus minus} S.D. of 3 independent experiments. Comparison was done with one-way ANOVA (p < 0.05) and Tukey's post hoc (p < 0.05) test. Supplementary Table 1. Transcription factors that are predicted by prediction algorithms, MotifScanner and CisGenome, to regulate the expression of all 4 miRNAs within 5000 base pairs upstream of each miRNA. The commons factors predicted for all 4 miRNAs were listed in the table. Supplementary Table 2. Selected genes from our predictions that overlap with the list of factors whose silencing cause radioresistance have been shown in Table 2.
Supplemental Figure 1 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Authors: Chen Haiming , Li Mingjie , Sanchez Eric , Wang Cathy S. , Lee Tiffany , Soof Camilia M. , Casas Christian E. , Cao Jasmin , Xie Colin , Udd Kyle A. , DeCorso Kevin , Tang George Y. , Spektor Tanya M. , Berenson James R.
Published: April 2023

Cloning of the pLenti6.2-hTRAF6dn vector. The TRAF6dn cDNA was cloned into PCRII TOPO vector to produce a 167-amino acid peptide and then sub-cloned into a pLenti6.2 expression vector (pLenti6.2-hTRAF6dn).
SUPPORTING INFORMATION from Olaparib, Monotherapy or with Ionizing Radiation, Exacerbates DNA Damage in Normal Tissues: Insights from a New p21 Reporter Mouse
Authors: McMahon Michael , Frangova Tania G. , Henderson Colin J. , Wolf C. Roland
Published: April 2023

Contains one Appendix, Supplementary Materials and Methods, Supplementary References, and Supplementary Figure Legends.
Supplementary Figures 1 - 4, Tables 1 - 2 from Triapine Disrupts CtIP-Mediated Homologous Recombination Repair and Sensitizes Ovarian Cancer Cells to PARP and Topoisomerase Inhibitors
Authors: Lin Z. Ping , Ratner Elena S. , Whicker Margaret E. , Lee Yashang , Sartorelli Alan C.
Published: April 2023

PDF file - 128K, Fig. S1. BRCA1 and BRCA2-defective EOC cells are sensitive to triapine. Fig. S2. Triapine abrogates olaparib-induced RPA phosphorylation in SKOV-3 cells. Fig. S3. Depletion of Chk1 partially reverses the inhibitory effects of triapine on RPA32 and CtIP phosphorylation. Fig. S4. Depletion of CtIP by siRNA. Table S1. CI values of triapine and olaparib combination determined by MTS viability assay in NTC and BRCA1-kd SKOV3 cells. Table S2A. CI values of triapine and olaparib combination at a constant ratio in NTC and BRCA1-kd SKOV3 cells (Fig. 2A). Table S2B. CI values of triapine and olaparib combination in SKOV-3 cells (Fig. 2B). Table S2C. CI values of triapine and olaparib combination in BG-1 cells (Fig. 2C). Table S2D. CI values of triapine and olaparib combination in PEO4 cells (Fig. 2D).
Supplemental Figure 1 from MUC1-C Represses the Crumbs Complex Polarity Factor CRB3 and Downregulates the Hippo Pathway
Authors: Alam Maroof , Bouillez Audrey , Tagde Ashujit , Ahmad Rehan , Rajabi Hasan , Maeda Takahiro , Hiraki Masayuki , Suzuki Yozo , Kufe Donald
Published: April 2023

MUC1-C regulates CRB3 expression.
Supplementary Tables 1-7 from Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma
Authors: Liang Chen , Qin Yi , Zhang Bo , Ji Shunrong , Shi Si , Xu Wenyan , Liu Jiang , Xiang Jinfeng , Liang Dingkong , Hu Qiangsheng , Ni Quanxing , Xu Jin , Yu Xianjun
Published: April 2023

Supplementary Table S1. Primers sequences used in the real-time PCR. Supplementary Table S2. siRNA oligoes used in the study. Supplementary Table S3. Primers sequences used in the quantitative ChIP. Supplementary Table S4. Clinicopathological features and correlation of MUC16 expression in PDAC in the TCGA cohorts. Supplementary Table S5. Univariate and multivariate Cox regression of Overall survival for patients with PDAC in the TCGA cohorts. Supplementary Table S6. Clinicopathological features and correlation of MUC16 expression in PDAC in the FUSCC cohorts. Supplementary Table S7. Univariate and multivariate Cox regression of Overall survival for patients with PDAC in the FUSCC cohorts.
Supplementary Table 1 from The Orphan Nuclear Receptor NR4A1 (Nur77) Regulates Oxidative and Endoplasmic Reticulum Stress in Pancreatic Cancer Cells
Authors: Lee Syng-Ook , Jin Un-Ho , Kang Jeong Han , Kim Sang Bae , Guthrie Aaron S. , Sreevalsan Sandeep , Lee Ju-Seog , Safe Stephen
Published: April 2023

PDF file - 20KB, Supplemental Table S1. List of real-time PCR primer sequences.
Supplementary Figure 3 from Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma
Authors: Liang Chen , Qin Yi , Zhang Bo , Ji Shunrong , Shi Si , Xu Wenyan , Liu Jiang , Xiang Jinfeng , Liang Dingkong , Hu Qiangsheng , Ni Quanxing , Xu Jin , Yu Xianjun
Published: April 2023

c-Myc overexpression increased the expression and shedding of CA125
Supplementary Figure 4 from The Orphan Nuclear Receptor NR4A1 (Nur77) Regulates Oxidative and Endoplasmic Reticulum Stress in Pancreatic Cancer Cells
Authors: Lee Syng-Ook , Jin Un-Ho , Kang Jeong Han , Kim Sang Bae , Guthrie Aaron S. , Sreevalsan Sandeep , Lee Ju-Seog , Safe Stephen
Published: April 2023

PDF file - 53KB, Supplemental Figure S4. DIM-C-pPhOH induces ER stress through inactivation of nuclear NR4A1.
Supplementary Figure 3 from The Orphan Nuclear Receptor NR4A1 (Nur77) Regulates Oxidative and Endoplasmic Reticulum Stress in Pancreatic Cancer Cells
Authors: Lee Syng-Ook , Jin Un-Ho , Kang Jeong Han , Kim Sang Bae , Guthrie Aaron S. , Sreevalsan Sandeep , Lee Ju-Seog , Safe Stephen
Published: April 2023

PDF file - 37KB, Supplemental Figure S3. Top 10 significant enriched canonical pathways altered by transfection of Panc-1 cells with siNR4A1.
Supplementary Tables 1 - 3 from Aberrant Methylation-Mediated Silencing of lncRNA MEG3 Functions as a ceRNA in Esophageal Cancer
Authors: Dong Zhiming , Zhang Aili , Liu Shengnan , Lu Fan , Guo Yanli , Zhang Guoqiang , Xu Fenglou , Shi Yabin , Shen Supeng , Liang Jia , Guo Wei
Published: April 2023

Supplementary Table 1. Clinicopathologic characteristics of esophageal squamous cell carcinoma cases. Supplementary Table 2. Primer sequences and reaction conditions of MEG3 used in this study. Supplementary Table 3. Methylation status of MEG3 in ESCC tumor tissues and corresponding normal tissues.
Supplementary Figure Legends from The Nuclear Pool of Tetraspanin CD9 Contributes to Mitotic Processes in Human Breast Carcinoma
Authors: Rappa Germana , Green Toni M. , Lorico Aurelio
Published: April 2023

Supplementary Figure Legends from The Nuclear Pool of Tetraspanin CD9 Contributes to Mitotic Processes in Human Breast Carcinoma
Supplementary figure legends from Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination
Authors: Frum Rebecca A. , Love Ian M. , Damle Priyadarshan K. , Mukhopadhyay Nitai D. , Palit Deb Swati , Deb Sumitra , Grossman Steven R.
Published: April 2023

Supplementary figure legends
Supplementary Figure 2 from The Nuclear Pool of Tetraspanin CD9 Contributes to Mitotic Processes in Human Breast Carcinoma
Authors: Rappa Germana , Green Toni M. , Lorico Aurelio
Published: April 2023

Lack of a nuclear CD9 pool in HuMEC.
Supplementary figure legends from Epigenetic Inactivation and Tumor-Suppressor Behavior of NGFR in Human Colorectal Cancer
Authors: Yang Zuli , Chen Hao , Huo Lijun , Yang Zihuan , Bai Yang , Fan Xinjuan , Ni Beibei , Fang Lekun , Hu Jun , Peng Junsheng , Wang Lei , Wang Jianping
Published: April 2023

Supplementary figure legends.
Kundu et al, Supplementary Figure 2 from Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival
Authors: Kundu Soumi , Xiong Anqi , Spyrou Argyris , Wicher Grzegorz , Marinescu Voichita D. , Edqvist Per-Henrik D. , Zhang Lei , Essand Magnus , Dimberg Anna , Smits Anja , Ilan Neta , Vlodavsky Israel , Li Jin-Ping , Forsberg-Nilsson Karin
Published: April 2023

Kundu et al, Supplementary Figure 2
Supplementary Tables from Epigenetic Inactivation and Tumor-Suppressor Behavior of NGFR in Human Colorectal Cancer
Authors: Yang Zuli , Chen Hao , Huo Lijun , Yang Zihuan , Bai Yang , Fan Xinjuan , Ni Beibei , Fang Lekun , Hu Jun , Peng Junsheng , Wang Lei , Wang Jianping
Published: April 2023

Supplementary Table S1-S4
Supplementary Figure S3 from Epigenetic Inactivation and Tumor-Suppressor Behavior of NGFR in Human Colorectal Cancer
Authors: Yang Zuli , Chen Hao , Huo Lijun , Yang Zihuan , Bai Yang , Fan Xinjuan , Ni Beibei , Fang Lekun , Hu Jun , Peng Junsheng , Wang Lei , Wang Jianping
Published: April 2023

Supplementary Figure S3. Methylation status of five CIMP locus in human CRC samples. Representative results of the methylation status of five CIMP locus in the CRC samples are shown. P, genomic DNA from placental tissue treated with SssI methylase or not was used as positive control for MSP; N, H2O was used as negative control for MSP, respectively.
Supplementary Figure S2 from Epigenetic Inactivation and Tumor-Suppressor Behavior of NGFR in Human Colorectal Cancer
Authors: Yang Zuli , Chen Hao , Huo Lijun , Yang Zihuan , Bai Yang , Fan Xinjuan , Ni Beibei , Fang Lekun , Hu Jun , Peng Junsheng , Wang Lei , Wang Jianping
Published: April 2023

Supplementary Figure S2. DNA hypermethylation of the p75NGFR promoter analyzed in 29 cancer types from the TCGA data portal. The relative positions of 9 analyzed methylation probes are indicated within a schematic map of the human p75NGFR gene. The red-labeled one is the same probe with our methyaltion array chip.
Supplementary Data Figure S1-2 from The Notch Pathway Promotes Osteosarcoma Progression through Activation of Ephrin Reverse Signaling
Authors: Yu Ling , Xia Kezhou , Gao Tian , Chen Jingteng , Zhang Zhengpei , Sun Xiangran , Simões Bruno M. , Eyre Rachel , Fan Zhengfu , Guo Weichun , Clarke Robert B.
Published: April 2023

Figure S1. Notch promotes osteosarcoma progression Figure S2. Notch pathway inhibits Eph forward signaling
Supplementary Figure Legend from Therapeutic Effect of Quinacrine, an Antiprotozoan Drug, by Selective Suppression of p-CHK1/2 in p53-Negative Malignant Cancers
Authors: Park Soyoung , Oh Ah-Young , Cho Jung-Hyun , Yoon Min-Ho , Woo Tae-Gyun , Kang So-mi , Lee Ho-Young , Jung Youn-Jin , Park Bum-Joon
Published: April 2023

Supplementary Figure Legend
Visual Abstract from Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver
Authors: Hori Takeshi , Saito Kosuke , Moore Rick , Flake Gordon P. , Negishi Masahiko
Published: April 2023

Visual Abstract
Supplemental Fig. 6 from Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver
Authors: Hori Takeshi , Saito Kosuke , Moore Rick , Flake Gordon P. , Negishi Masahiko
Published: April 2023

p38 phosphorylation levels and its involvement in the Cyp2b10 gene expression.
Supplementary Table S1 from Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma
Authors: Deng Houliang , Zeng Jianming , Zhang Ting , Gong Longcai , Zhang Hongjie , Cheung Edwin , Jones Chris , Li Gang
Published: April 2023

Primers used in the study.
Supplementary File 2 from Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma
Authors: Deng Houliang , Zeng Jianming , Zhang Ting , Gong Longcai , Zhang Hongjie , Cheung Edwin , Jones Chris , Li Gang
Published: April 2023

A list of cancer-testis antigen genes: the custom Gene Matrix Transposed (GMT) file containing the list of cancer testis antigens used for GSEA in the study.
Supplemental Fig. 3 from Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver
Authors: Hori Takeshi , Saito Kosuke , Moore Rick , Flake Gordon P. , Negishi Masahiko
Published: April 2023

Contact regions of CAR to GADD45B.
Supplemental Fig. 2 from Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver
Authors: Hori Takeshi , Saito Kosuke , Moore Rick , Flake Gordon P. , Negishi Masahiko
Published: April 2023

Characterization of interactions in CAR, GADD45B, MKK6, and p38 MAPK.
Supplemental Fig. 1 from Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver
Authors: Hori Takeshi , Saito Kosuke , Moore Rick , Flake Gordon P. , Negishi Masahiko
Published: April 2023

Phosphorylation and interactions of p38 MAPK.