bluuebunny/crossref_metadata_2025 huggingface dataset:
HER2-Orientated Therapy in Early and Metastatic Breast Cancer
Authors: Iborra Severine , Stickeler Elmar
Published: December 2016

Due to the enhanced understanding of molecular oncology and signaling pathways in breast cancer (BC), therapy management has undergone a major transformation, especially with the emergence of treatment tailored to individual disease characteristics. In the case of HER2-positive early or metastatic BC, targeted therapies are well established and remain a major focus of ongoing research. The introduction of anti-HER2 biologicals such as trastuzumab, pertuzumab, and T-DM1 has made targeted and personalized treatment possible and has clearly improved disease-free and overall survival in patients with HER2-positive BC. Moreover, neoadjuvant chemotherapy represents a well-established and often favored option for patients with operable BC and a clear indication for postoperative chemotherapy (such as HER2-positive BC). Other trials are trying to identify additional surrogate markers for therapy response and clinical outcome in the neoadjuvant setting and that way open up new perspectives with a possible de-escalation of classical treatment in favor of targeted therapy.
A Cost-Effective Approach to the Diagnosis and Management of Acute Infectious Encephalitis
Authors: Misra Usha Kant , Mani Vinita Elizabeth , Kalita Jayantee
Published: December 2016

Setting: A tertiary care teaching hospital in India. Objective: To report a syndromic approach to acute encephalitis syndrome (AES) and propose a cost-effective model. Study design: AES patients were categorized by the presence or absence of myalgia/rash into systemic and neurological AES. The patients with systemic AES were investigated for dengue, scrub typhus, leptospira, chikungunya, and malaria, and those with neurological AES were investigated for herpes and Japanese encephalitis (JE). Sensitivity and specificity of syndromic categorization were tested, and cost effectiveness was calculated. Results: There were 210 patients with infectious AES; neurological in 45 and systemic in 165. Specific etiology could be found in 130 (62%) patients, and after excluding 36 patients with co-infections, 94 patients were tested for sensitivity and specificity. Twenty patients had neurological AES (herpes 12, JE 8), and 74 systemic (scrub typhus 42, dengue 20, malaria 6, leptospira 6). The absence of myalgia/rash categorized neurological AES with 100% specificity. In neurological AES, thalamic involvement predicted JE with 100% specificity. In systemic AES, differentiation could not be made between etiologies based on hypotension, thrombocytopenia, and muscle, liver, and kidney dysfunction. In these patients, MRI and acyclovir therapy were warranted, saving cost. By targeted investigations and treatment, the cost was reduced by 70%. Conclusions: A syndromic approach to AES and goal-directed investigations and treatment substantially reduces the cost of management.
Polarização de macrófagos e as complicações da Obesidade: o que podemos aprender com os modelos experimentais
Authors: Cação Brendha , Simões Ávaro , Mendes Cícero , Souza Heraldo P.
Published: December 2016

Clinical and experimental evidences pointed to the role of immune cells and inflammatory mediators on the development of diseases in obese patients. Therefore, it is our objective to explore experimental studies that approach the relationship between the different types of inflammatory reaction inside the adipose tissue, particularly the macrophage polarization and the development of obesity complications. Further, we intend to speculate how to translate this knowledge, obtained from experimental studies, to treatments applicable to the human diseases. PubMed database was sought using the terms “obesity”, “macrophage” and “polarization”. After applying the filters “Language - English” and “Species - Animals”, we arrived to 90 references. Sixty-two were excluded for being reviews or not related to the main subject. Results in experimental models of obesity pointed a relevant correlation between the macrophage polarization to a type 1 response (M1) inside white adipose tissue and the development of insulin resistance, diabetes and other complications of obesity. Several articles report strategies to shift to a type 2 phenotype (M2), using drugs or lifestyle changes. How these findings could be translated to new human treatments is still an open question that only well designed researches could answer.
Castration-resistant prostate cancer: current status of therapy with Radium-223 associated with anti-androgens (enzalutamide and abiraterone) - a systematic literature review
Authors: Added Filho Daniel Abdalla , Benedetto Filho Marcos Sidney , Sapienza Marcelo Tatit
Published: December 2016

BACKGROUND. Recently, a new range of therapeutic options became available for men with advanced castration-resistant prostate cancer (CRPC), including antiandrogens (abiraterone acetate, enzalutamide), taxanes (docetaxel, cabazitaxel) and a radionuclide (radium-223). The development of abiraterone and enzalutamide, as well as the advent of Ra-223, led to significant improvements in CRPC clinical outcomes. However, there are currently few data regarding the optimal sequence or concomitant use of Ra-223 with these most recently approved endocrine agents. OBJECTIVE. To systematically identify and analyse articles that brings information about the concomitant or sequential use of radium-223 (Ra-223) associated with antiandrogenic drugs (abiraterone or enzalutamide) in the therapy of CRPC. METHODS. PubMed (mesh and free terms), Scopus and Clinical Trials were searched to identify published articles about the sequential or association use of radium-223. RESULTS. A total of 484 references were identified by the literature search and after exclusion and inclusion criteria 36 were screened. 4 publications that met the selection criteria were included in this review; of these 2 were cost-effectiveness studies and 2, case series. Overall, safety profiles in relation to therapy with Ra-223 were similar regardless of use or not of enzalutamide or abiraterone. Response were higher for the combinations of Ra-223 with abiraterone while with enzalutamide no improvements were found. The drugs do not seem to have great differences in costs and there is still no consensus on the most cost-effective treatment in the short and long term. CONCLUSION. Further studies are necessary to evaluate the best treatment regimen (concurrent or sequential) of Ra-223 and new antiandrogens. By now, data show that the best association of use may be with abiraterone. There are ongoing clinical trials that aim to precisely study the use of these drugs together, therefore in the next few years this situation tends to change.
Pasto Niilista, repasto humanista, convivas fantasmas: O jogo com a vida (e a morte) em Breakfast of Champions, de Kurt Vonnegut
Authors: Paz Ravel Giordano
Published: December 2016

O artigo discute a presença de elementos autobiográficos no romance Breakfast of champions, do escritor estadunidense Kurt Vonnegut, situando-os na economia da prosa experimental-comunicativa do autor e tentando demonstrar como o que se pode denominar um jogo com a vida ajuda a dar profundidade e complexidade aos jogos narracionais e às ambiguidades ideológicas desse romance.
Timing of Carotid Revascularization Procedures After Ischemic Stroke
Authors: Reznik Michael , Kamel Hooman , Gialdini Gino , Pandya Ankur , Navi Babak B. , Gupta Ajay
Published: December 2016

Background and Purpose—

In 2006, the American Heart Association recommended that carotid revascularization generally occurs within 2 weeks of stroke based on data from 2 trials of carotid endarterectomy (CEA). We aimed to determine whether the time between stroke and CEA or carotid artery stenting (CAS) has decreased and whether the proportion of procedures occurring within 14 days has increased.

Methods—

Using validated International Classification of Diseases, Ninth Revision, Clinical Modification codes and administrative claims data from nonfederal hospitals in CA, FL, and NY, we identified patients with ischemic stroke who underwent CEA or CAS within 90 days of an ischemic stroke from 2005 to 2013. Our outcomes were the number of days between stroke and CEA/CAS and the proportion of patients undergoing CEA/CAS within the recommended 14-day period. We assessed temporal trends using nonparametric correlation, the χ
2
test for trend, and logistic regression.

Results—

We identified 16 298 patients with ischemic stroke who underwent CEA/CAS within 90 days. The time from stroke to CEA/CAS decreased from 25 days (interquartile range, 5–48 days) in 2005 to 6 days (interquartile range, 3–17 days) in 2013 (
P
<0.001). The proportion of patients who underwent CEA/CAS within 14 days of stroke increased from 40% (95% confidence interval, 37%–43%) in 2005 to 73% (95% confidence interval, 71%–76%) in 2013 (
P
<0.001). These temporal trends remained significant after adjustment for patient demographics and comorbidities.

Conclusions—

Since 2005, revascularization for symptomatic carotid disease has been occurring progressively sooner after ischemic stroke.
Beating Time in the Slow Movements: Bensaïd’s Revolutionary Rhythms
Authors: Lafrance Xavier , Sears Alan
Published: December 2016

Daniel Bensaïd was prominent among the revolutionary thinkers and activists who emerged from the mass insurgency of the 1960s, a period in which anti-capitalist organisers had genuine social weight grounded in connections to broad layers of the working class and radical movements. As the neoliberal offensive developed, working-class and allied movements experienced crucial defeats that marginalised anti-capitalist theory and practice. Bensaïd developed a unique theoretical analysis of radical mobilising during the neoliberal period, at once grounded in the history of revolutionary organising and audaciously open-ended in assessing the impact of capitalist restructuring and the employers’ offensive. The basis of his theoretical renewal lay in a new approach to understanding temporality that undercut any sense of socialist inevitability, and a commitment to revolutionary pluralism that was crucially located in the political sphere.
Biography, Life History and Orality
Authors: Richter-Devroe Sophie
Published: December 2016

The paper traces the ordinary—yet extraordinary—life story of a Bedouin woman, Amneh, in historic Southern Palestine from the 1930s to the 1970s. Amneh’s oral narratives and memories combine the personal and the political, drawing a picture of the lives that the often forgotten Palestinian Bedouin population of the South lived before, during and after theNakba, the Palestinian Catastrophe of 1948. Her counter-narrative challenges and complicates the hegemonic settler-colonial, ethno-nationalist, elite and male-dominated historiography of the region, and confirms her as an historical actor who finds her ways through difficult social, political, economic and cultural constraints. Although unique, her story is not exceptional, nor is it representative of ‘Bedouin women of the Naqab’. Rather, it offers a lens through which the much more intricate and messy historical realities in the Naqab can be unfolded. As such, Amneh’s biography, as told by her, is also telling of the wider social and political dynamics, relations and events in the region at the time.
Whether Korea’s Export Permit Regulations on a Strategic Good under the Foreign Trade Act is a Peremptory Norm
Authors: Park Eon Kyung , Lee Seokwoo
Published: December 2016

Ever since the problem of the illegal exportation of the Mugunghwa Satellite No. 3 was raised at the parliamentary audit in 2013, a number of concerns about the follow-up measures are still being raised. Doubts have been raised about whether it was the right decision, as a legal matter, for the Science, ict and Future Planning Ministry to decide that the sale of Mugunghwa Satellite No. 3 was invalid on the ground that the Foreign Trade Act is a mandatory rule. Even in political terms, it is necessary to review whether the repurchase of Mugunghwa Satellite No. 3 is the best option. Under these circumstances, we must review whether retrieving Mugunghwa Satellite No. 3, which has a short lifespan, by paying a high price is a necessary measure to take from a national strategic perspective.
The Importance of the Shape of Cloud Droplet Size Distributions in Shallow Cumulus Clouds. Part II: Bulk Microphysics Simulations
Authors: Igel Adele L. , van den Heever Susan C.
Published: December 2016

In this two-part study, relationships between the cloud gamma size distribution shape parameter, microphysical processes, and cloud characteristics of nonprecipitating shallow cumulus clouds are investigated using large-eddy simulations. In Part I, the dependence of the shape parameter (which is closely related to the distribution width) on cloud properties and processes was investigated. However, the distribution width also impacts cloud process rates and in turn cloud properties, and it is this aspect of the relationship that is explored in Part II and is discussed in the context of aerosol–cloud interactions. In simulations with a bulk microphysics scheme, it is found that the evaporation rates are much more sensitive to the value of the shape parameter than to the condensation rates. This is due to changes in both the rate of removal of mass and the rate of removal of fully evaporated droplets. As a result, cloud properties such as droplet number concentration, mean droplet diameter, and cloud fraction are strongly impacted by the value of the shape parameter, particularly in the subsaturated regions of the clouds. These changes can be on the same order of magnitude as changes due to increasing or decreasing the aerosol concentration by a factor of 16. Particular attention is paid to the impact of the shape parameter on cloud albedo. The cloud albedo increases as the shape parameter is increased as a result of the changes in evaporation. The magnitude of the increase is about 4 times larger than previous estimates. However, this increase in cloud albedo is largely offset by a decrease in the cloud fraction, which results in only small increases to the domain-average albedo. Implications for the aerosol relative dispersion effect are discussed.
Effects of Rotation Rate and Seasonal Forcing on the ITCZ Extent in Planetary Atmospheres
Authors: Faulk Sean , Mitchell Jonathan , Bordoni Simona
Published: December 2016

The authors study a wide range of atmospheric circulations with an idealized moist general circulation model to evaluate the mechanisms controlling intertropical convergence zone (ITCZ) migrations. They employ a zonally symmetric aquaplanet slab ocean of fixed depth and force top-of-atmosphere insolation to remain fixed at the pole for an “eternal solstice” simulation and also vary seasonally for a range of rotation rates, keeping all other parameters Earth-like. For rotation rates ΩE/8 and slower, a transient maximum in zonal-mean precipitation appears at the summer pole; however, the ITCZ associated with the ascending branch of the Hadley circulation lies at ~60°. The authors assess how widely used predictors of the ITCZ position perform in this wide parameter space. Standard predictors based on different estimates of the Hadley cell’s poleward extent are correlated with but overestimate off-equatorial ITCZ locations. Interestingly, in the eternal-solstice case for Earth’s rotation rate, the ITCZ remains at subtropical latitudes even though the lower-level moist static energy maximizes at the summer pole. While seemingly at odds with convective quasi-equilibrium arguments, this can happen because at Earth’s rotation rates, the thermal stratification set in convective regions can only be communicated within the tropics, where temperature gradients are constrained to be weak. The authors therefore develop an understanding of the ITCZ’s position based on top-of-atmosphere energetics and the boundary layer momentum budget and argue that friction and pressure gradient forces determine the region of maximum convergence, offering a modified dynamical perspective on the monsoon-like seasonal weather patterns of terrestrial planets.
Indian Ocean Dipole Modes Associated with Different Types of ENSO Development
Authors: Fan Lei , Liu Qinyu , Wang Chunzai , Guo Feiyan
Published: December 2016

This study identifies several modes of coevolution of various types of El Niño–Southern Oscillation (ENSO) and Indian Ocean dipole (IOD) by performing rotated season-reliant empirical orthogonal function (S-EOF) analysis with consideration of ENSO asymmetry. The first two modes reveal that early-onset ENSO is associated with subsequent strong IOD development, whereas late-onset ENSO forces an obscure IOD pattern with marginal SST anomalies in the western Indian Ocean. Further studies show that El Niño starting before early summer can more easily force an IOD event than that starting in late summer or fall, even when they are of equivalent magnitudes. This is because the atmospheric responses over the Indian Ocean to the eastern Pacific warming are in sharp contrast between early and late summer. Early-onset (late onset) El Niño can (cannot) cause favorable atmospheric circulation conditions over the Indian Ocean for inducing the western Indian Ocean warming, which facilitates the subsequent IOD development. In addition, the different propagations of ocean dynamic Rossby waves during the early- or late-onset types of ENSO are also accountable for the different IOD development. For the higher-order modes, the rotated S-EOF of “Niño only” cases shows a coevolution between a negative IOD mode and a date line Pacific El Niño, with warm sea surface temperature anomalies originating from the northern Pacific meridional mode.
Factors Contributing to Record-Breaking Heat Waves over the Great Plains during the 1930s Dust Bowl
Authors: Cowan Tim , Hegerl Gabriele C. , Colfescu Ioana , Bollasina Massimo , Purich Ariaan , Boschat Ghyslaine
Published: December 2016

Record-breaking summer heat waves were experienced across the contiguous United States during the decade-long “Dust Bowl” drought in the 1930s. Using high-quality daily temperature observations, the Dust Bowl heat wave characteristics are assessed with metrics that describe variations in heat wave activity and intensity. Despite the sparser station coverage in the early record, there is robust evidence for the emergence of exceptional heat waves across the central Great Plains, the most extreme of which were preconditioned by anomalously dry springs. This is consistent with the entire twentieth-century record: summer heat waves over the Great Plains develop on average ~15–20 days earlier after anomalously dry springs, compared to summers following wet springs. Heat waves following dry springs are also significantly longer and hotter, indicative of the importance of land surface feedbacks in heat wave intensification. A distinctive anomalous continental-wide circulation pattern accompanied exceptional heat waves in the Great Plains, including those of the Dust Bowl decade. An anomalous broad surface pressure ridge straddling an upper-level blocking anticyclone over the western United States forced substantial subsidence and adiabatic warming over the Great Plains, and triggered anomalous southward warm advection over southern regions. This prolonged and amplified the heat waves over the central United States, which in turn gradually spread westward following heat wave emergence. The results imply that exceptional heat waves are preconditioned, triggered, and strengthened across the Great Plains through a combination of spring drought, upper-level continental-wide anticyclonic flow, and warm advection from the north.
Impact of Atmospheric Blocking on South America in Austral Summer
Authors: Rodrigues Regina R. , Woollings Tim
Published: December 2016

This study investigates atmospheric blocking over eastern South America in austral summer for the period of 1979–2014. The results show that blocking over this area is a consequence of propagating Rossby waves that grow to large amplitudes and eventually break anticyclonically over subtropical South America (SSA). The SSA blocking can prevent the establishment of the South Atlantic convergence zone (SACZ). As such, years with more blocking days coincide with years with fewer SACZ days and reduced precipitation. Convection mainly over the Indian Ocean associated with Madden–Julian oscillation (MJO) phases 1 and 2 can trigger the wave train that leads to SSA blocking whereas convection over the western/central Pacific associated with phases 6 and 7 is more likely to lead to SACZ events. It is found that the MJO is a key source of long-term variability in SSA blocking frequency. The wave packets associated with SSA blocking and SACZ episodes differ not only in their origin but also in their phase and refraction pattern. The tropopause-based methodology used here is proven to reliably identify events that lead to extremes of surface temperature and precipitation over SSA. Up to 80% of warm surface air temperature extremes occur simultaneously with SSA blocking events. The frequency of SSA blocking days is highly anticorrelated with the rainfall over southeast Brazil. The worst droughts in this area, during the summers of 1984, 2001, and 2014, are linked to record high numbers of SSA blocking days. The persistence of these events is also important in generating the extreme impacts.
Impacts of Land-Use/Land-Cover Change on Afternoon Precipitation over North America
Authors: Chen Liang , Dirmeyer Paul A.
Published: December 2016

This study investigates the impacts of historical land-cover change on summer afternoon precipitation over North America using the Community Earth System Model. Using land–atmosphere coupling metrics, this study examines the sensitivity of afternoon atmospheric conditions to morning land surface states and fluxes that are altered by land-cover changes before and since 1850. The deforestation in the eastern United States prior to 1850 leads to increased latent but decreased sensible heat flux during the morning and a reduction in afternoon precipitation over the southern regions of the U.S. East Coast. The agricultural expansion over the Great Plains since preindustrial times shows similar effects on surface fluxes but results in a significant widespread increase in precipitation over the crop area. The coupling metrics exhibit a strong positive soil moisture–precipitation relationship over the Great Plains. Impacts of land-cover change on precipitation manifest through changes in rainfall frequency, rather than intensity, that are largely controlled by the distribution of CAPE as the trigger of convective precipitation. However, deforestation and later reforestation over the eastern United States, where coupling properties are different than the Great Plains, do not have as dominant an effect on afternoon precipitation. Additionally, precipitation over parts of the U.S. Southwest decreases in this model during the earlier period of East Coast deforestation, owing to changes in the large-scale circulation over North America driven by land-use changes prior to 1850.
Global Optimization of an Analog Method by Means of Genetic Algorithms
Authors: Horton Pascal , Jaboyedoff Michel , Obled Charles
Published: December 2016

Analog methods are based on a statistical relationship between synoptic meteorological variables (predictors) and local weather (predictand, to be predicted). This relationship is defined by several parameters, which are often calibrated by means of a semiautomatic sequential procedure. This calibration approach is fast, but has strong limitations. It proceeds through successive steps, and thus cannot handle all parameter dependencies. Furthermore, it cannot automatically optimize some parameters, such as the selection of pressure levels and temporal windows (hours of the day) at which the predictors are compared. To overcome these limitations, the global optimization technique of genetic algorithms is considered, which can jointly optimize all parameters of the method, and get closer to a global optimum, by taking into account the dependencies of the parameters. Moreover, it can objectively calibrate parameters that were previously assessed manually and can take into account new degrees of freedom. However, genetic algorithms must be tailored to the problem under consideration. Multiple combinations of algorithms were assessed, and new algorithms were developed (e.g., the chromosome of adaptive search radius, which is found to be very robust), in order to provide recommendations regarding the use of genetic algorithms for optimizing several variants of analog methods. A global optimization approach provides new perspectives for the improvement of analog methods, and for their application to new regions or new predictands.
Kinematic and Microphysical Significance of Lightning Jumps versus Nonjump Increases in Total Flash Rate
Authors: Schultz Christopher J. , Carey Lawrence D. , Schultz Elise V. , Blakeslee Richard J.
Published: December 2016

Thirty-nine thunderstorms are examined using multiple-Doppler, polarimetric, and total lightning observations to understand the role of mixed-phase kinematics and microphysics in the development of lightning jumps. This sample size is larger than those of previous studies on this topic. The principal result of this study is that lightning jumps are a result of mixed-phase updraft intensification. Larger increases in intense updraft volume (≥10 m s−1) and larger changes in peak updraft speed are observed prior to lightning jump occurrence when compared to other nonjump increases in total flash rate. Wilcoxon–Mann–Whitney rank sum testing yields p values ≤ 0.05, indicating statistical independence between lightning jump and nonjump distributions for these two parameters. Similar changes in mixed-phase graupel mass magnitude are observed prior to lightning jumps and nonjump increases in total flash rate. The p value for the graupel mass change is p = 0.096, so jump and nonjump distributions for the graupel mass change are not found to be statistically independent using the p = 0.05 significance level. The timing of updraft volume, speed, and graupel mass increases is found to be 4–13 min in advance of lightning jump occurrence. Also, severe storms without lightning jumps lack robust mixed-phase updrafts, demonstrating that mixed-phase updrafts are not always a requirement for severe weather occurrence. Therefore, the results of this study show that lightning jump occurrences are coincident with larger increases in intense mixed-phase updraft volume and peak updraft speed than smaller nonjump increases in total flash rate.
Attempted suicide by ingestion of hair dye containing p-phenylenediamine: a case report
Authors: Beshir Lamis , Kaballo Babiker , Young Donald
Published: December 2016

Para-phenylenediamine is widely used as a chemical in hair dyes and in combination with henna. This dye is used to paint the body for decorative reasons, to speed the processing time of henna and to intensify the results. Para-phenylenediamine is widely used in the Middle East, North Africa and India.

Several reports have been published of the fatal ingestion of hair dye containing para-phenylenediamine. Here, we describe the case of a 14-year-old girl who ingested the compound but whose prompt treatment prevented her death. Ingestion of para-phenylenediamine produces a typical triad of angioneurotic oedema, rhabdomyolysis and acute tubular necrosis. Awareness of signs of these associated conditions in our patient, together with a comprehensive history, facilitated appropriate treatment to be instituted. We document the steps we took to enable her complete physical recovery.
Reflective Tape Applied to Bicycle Frame and Conspicuity Enhancement at Night
Authors: Costa Marco , Bonetti Leonardo , Bellelli Manuela , Lantieri Claudio , Vignali Valeria , Simone Andrea
Published: December 2016

Objective:

Four studies were conducted to assess bicyclist conspicuity enhancement at night by the application of reflective tape (ECE/ONU 104) to the bicycle rear frame and to pedal cranks.

Background:

Previous studies have tested the benefits of reflective markings applied to bicyclist clothing. Reflective jackets however need to be available and worn while reflective markings enhance conspicuity without any active behavior by the bicyclist.

Method:

In the first study, reflective tape was applied to the rear frame. Detection distance was compared in four conditions: control, rear red reflector, high visibility jacket, and reflective tape. In the second study, the same conditions were studied with night street lighting on and off. In the third study, detection and recognition distances were evaluated in rainy conditions. In the fourth study, visibility was assessed with the reflective tape applied to pedal cranks.

Results:

In the first study, the application of reflective markings resulted in a detection distance of 168.28 m. In the second study, the detection distance with reflective markings was 229.74 m with public street light on and 256.41 m with public street light off. In rainy conditions, detection distance using the reflective markings was 146.47 m. Reflective tape applied to pedal cracks resulted in a detection distance of 168.60 m.

Conclusion:

Reflective tape applied to the rear bicycle frame can considerably increase bicyclist conspicuity and safety at night.

Application:

Reflective tape is highly recommended to complement anterior and rear lights in bicycle riding at night.
Spatial variations in personal insolvency choices: The role of stigma and social capital
Authors: Bishop Paul
Published: December 2016

This article offers an explanation for the wide spatial variations in choice of insolvency route by personal debtors across local authorities in England and Wales. It is argued that formal bankruptcy has a more negative impact on social capital through stigma effects than the alternative of Individual Voluntary Arrangements. Consequently, spatial variations in choices are related to variations in social capital. The hypotheses derived from this approach are tested through the use of spatial econometric models utilising data from England and Wales. The results provide support for a positive link between variables related to social capital (age, mobility and home ownership) and choice of IVAs. It is argued that avoidance of stigma costs provides an explanation for the apparent paradox of the significant growth of IVAs despite their high cost to debtors compared to bankruptcy. Whilst there is only limited support for impacts directly related to the urban-rural environment, significant spatial interdependencies in choices across neighbouring areas are also uncovered.
Exploring the synergistic economic benefit of enhancing neighbourhood bikeability and public transit accessibility based on real estate sale transactions
Authors: Li Wei , Joh Kenneth
Published: December 2016

Planners and policy makers are increasingly promoting biking and public transit as viable means of transportation. The integration of bicycling and transit has been acknowledged as a strategy to increase the mode share of bicycling and the efficiency of public transit by solving the first- and last-mile problem. However, the economic outcomes of jointly promoting neighbourhood bikeability and transit accessibility are still poorly understood. This study aims to assess the property value impact of neighbourhood bikeability, transit accessibility, and their synergistic effect by analysing the single-family and condominium property sale transactions during 2010–2012 in Austin, Texas, USA. Our Cliff-Ord spatial hedonic modelling approach, which is also known as the general spatial model (or SAC), controls for the spatial dependent effects in the sale price and the error terms simultaneously. In order to quantify neighbourhood bikeability and transit accessibility, we use Bike Score and Transit Score as publicly available indices. We have assessed how residents’ willingness to pay (WTP) for bikeability and transit accessibility depend on various socio-demographic and built-environment factors, and whether the WTP is influenced by the bicycle-transit synergy. The results from this research show that jointly enhancing bikeability and transit accessibility can generate positive synergistic effects on property values. The effects would behoove policy makers to pursue the coordination of bicycle master plans with regional transit plans and to consider strategies of spatially-joint bicycle and transit investment.
Gentrification, displacement and the arts: Untangling the relationship between arts industries and place change
Authors: Grodach Carl , Foster Nicole , Murdoch James
Published: December 2016

The arts have long played a role in debates around gentrification and displacement, yet their roles and impacts as change agents are not clear-cut. According to the standard account, artists facilitate gentrification and ultimately engender the displacement of lower income households, but more recent research complicates the accepted narrative. This article seeks to untangle the relationship between the arts, gentrification and displacement through a statistical study of neighbourhood-level arts industry activity within large US regions. The findings indicate that the standard arts-led gentrification narrative is too generalised or simply no longer applicable to contemporary arts-gentrification processes. Rather, the arts have multiple, even conflicting relationships with gentrification and displacement that depend on context and type of art. These results have important implications for how we study the role of the arts in neighbourhood change and for how governments approach the arts and creative industries in urban policy.
Youthful socialities in Australia’s urban multiculture
Authors: Harris Anita
Published: December 2016

This article considers the function of friendship as a form of urban relation for young people living in working class areas of Australia’s multicultural capital cities. These neighbourhoods are characterised by very high diversity, significant socioeconomic disadvantage and large youth populations, and over the last five years many have received the largest influx of refugees and migrants of any Australian municipality. Against this backdrop, this article investigates the ways that sociality is produced amongst young people of many backgrounds who must constantly negotiate interethnic propinquity in their daily lives. It explores how young people create ways of being together beyond and beneath the imperatives of formal social cohesion initiatives to participate in harmonious community-making. It argues that everyday forms of convivial co-habitation are produced and regulated through friendship relations and networks that embed mix in daily life, and these can serve to recognise and manage, rather than eliminate, intensity, conflict and ambivalence. It suggests that such practices of sociality complicate mainstream policy endeavours, and can offer some important and hopeful ways to expand theorisation of social relations in the multicultural city.
Canaries in the mine? Gay community, consumption and aspiration in neoliberal Washington, DC
Authors: Lewis Nathaniel M
Published: December 2016

Gay men have been implicated in neoliberal urban development strategies (e.g. the creative city) as a ‘canary’ population that forecasts growth. Paradoxically, both neoliberal re-development of North American inner-cities and the ways in which gay men become neoliberalised as individuals contribute to the dissolution of urban gay communities. In contrast to discourses of homonormativity, which suggest that gay men’s declining attachments to gay communities stem from new equalities and consequent desires to assimilate into the mainstream, this article argues that gay men in DC have internalised neoliberal discourses that call for career development, home ownership and social hypermobilities. The narratives of 24 gay-identified men living in DC indicate that the social and spatial dissolution of the gay community is linked with individual aspirations that are increasingly difficult to achieve. These aspirations include career advancement in a transient local economy, property ownership in an out-of-reach market, and the attainment of social status based on an ability to move through multiple neighbourhoods and venues with ease. As might be expected, African American and working class men are often left beyond the fray of these new neoliberal ideals.
Gentrification and the flexibilisation of spatial control: Policing sex work in Germany
Authors: Künkel Jenny
Published: December 2016

Gentrification has often been linked to the spatial displacement of the marginalised, including prostitutes. However, in Germany, the legal spaces of prostitution are to a certain extent defensible, and gentrification processes often cover larger parts of inner cities, leaving little room for displacement. Using the example of prostitution in Frankfurt, this paper analyses how police make sense of and shape the shifting geographies of gentrification. It shows how spatial displacement is partially subsumed by two additional police strategies: intensifying attempts to discursively appease protesting citizens, and flexibilising the containment of prostitution in the inner city (e.g. by keeping street scenes on the move and lobbying for temporary brothel licenses).
From bauxite to cooking pots: Aluminum, chemistry, and West African artisanal production
Authors: Osborn Emily Lynn
Published: December 2016

The history of aluminum’s transformation from a precious to a commonplace metal over the course of the late nineteenth and twentieth centuries has frequently been told as a narrative about intrepid western chemists, whose discoveries made it possible for industrialized manufacturers to make the metal global. This paper questions both the singularity of that discovery and the inevitability of aluminum’s global dominance as a ‘modern’ material of manufacture. It does so by considering the history of aluminum in West Africa and the ways in which artisans in that region domesticated the substance to an artisanal mode of production and developed quotidian chemical knowledge of it in the process. Considering aluminum from the perspective of West Africa suggests that aluminum may not have been discovered once, but many times, and that everyday material engagements can inspire forms of chemical knowhow that operate well beyond the bounds of the laboratory and industrial manufacturing plant.
The Auditory Kuleshov Effect: Multisensory Integration in Movie Editing
Authors: Baranowski Andreas M. , Hecht H.
Published: December 2016

Almost a hundred years ago, the Russian filmmaker Lev Kuleshov conducted his now famous editing experiment in which different objects were added to a given film scene featuring a neutral face. It is said that the audience interpreted the unchanged facial expression as a function of the added object (e.g., an added soup made the face express hunger). This interaction effect has been dubbed “Kuleshov effect.” In the current study, we explored the role of sound in the evaluation of facial expressions in films. Thirty participants watched different clips of faces that were intercut with neutral scenes, featuring either happy music, sad music, or no music at all. This was crossed with the facial expressions of happy, sad, or neutral. We found that the music significantly influenced participants’ emotional judgments of facial expression. Thus, the intersensory effects of music are more specific than previously thought. They alter the evaluation of film scenes and can give meaning to ambiguous situations.
The Effect of Differences in Day and Night Lighting Distributions on Drivers' Speed Perception
Authors: Kim Jonathan D. , Perrone John A. , Isler Robert B.
Published: December 2016

Previous research has shown that changes to contrast levels in the visual environment caused by fog can affect drivers' perceptions of speed. It is not easy, however, to extrapolate these results to other driving scenarios in which contrast is affected, such as during nighttime driving, because the measure of contrast is more complex when considering factors such as the illumination provided by headlights. Therefore, we investigated the differences in lighting distribution patterns between day- and nighttime driving on speed perception using prerendered 3D scenarios representing driving on a rural road. A two-alternative forced-choice design based on the method of constant stimuli was utilised, with 32 participants viewing a series of pairs of scenarios (day vs. night driving) from a driver's perspective while indicating for each pair whether the second scenario was faster or slower than the first scenario. Our results indicated that speed discrimination accuracy was minimally affected by changes in lighting distribution patterns between day and night.
Short-Form Audit Instrument for Assessing Corner Store Healthfulness
Authors: DeWeese Robin S. , Todd Michael , Karpyn Allison , Yedidia Michael J. , Kennedy Michelle , Bruening Meg , Wharton Christopher M. , Ohri-Vachaspati Punam
Published: December 2016

Purpose:

To develop a valid and feasible short-form corner store audit tool (SCAT) that could be used in-store or over the phone to capture the healthfulness of corner stores.

Design:

Nonexperimental.

Setting:

Four New Jersey cities.

Subjects:

Random selection of 229 and 96 corner stores in rounds 1 and 2, respectively.

Measures:

An adapted version of the Nutrition Environment Measures Survey for Corner Stores (NEMS-CS) was used to conduct in-store audits. The 7-item SCAT was developed and used for round 2 phone audits.

Analysis:

Exploratory factor analysis and item response theory were used to develop the SCAT.

Results:

The SCAT was highly correlated with the adapted NEMS-CS ( r = .79). Short-form corner store audit tool scores placed stores in the same healthfulness categories as did the adapted NEMS-CS in 88% of the cases. Phone response matches indicated that store owners did not distinguish between 2% and low-fat milk and tended to round up the fruit and vegetable count to 5 if they had fewer varieties.

Conclusion:

The SCAT discriminates between higher versus lower healthfulness scores of corner stores and is feasible for use as a phone audit tool.
In the shadow of technology
Authors: Mikkonen Simo
Published: December 2016

The study of the cultural Cold War and East–West interaction outside diplomacy and high politics has emerged as an important research field during the last two decades. With a few exceptions, however, scholarly interaction has been overshadowed by other forms of interaction. Existing research has mostly paid attention to technological exchange and to espionage, which was at times connected with scientific exchanges across the Iron Curtain. This article discusses scholarly exchanges in the human sciences between Finland and the Soviet Union. Even though Finland was a western-style democracy with a market economy, it had close political ties with the Soviet Union, which allowed for the development of active scholarly connections between the countries. This article discusses the emergence of such connections in the human sciences and the reasons for their rapid expansion in the 1970s.
After Nikolai Bukharin
Authors: Omodeo Pietro D.
Published: December 2016

This article addresses the ideological context of twentieth-century history of science as it emerged and was discussed at the threshold of the Cold War. It is claimed that the bifurcation of the discipline into a socio-economic strand and a technical-intellectual one (the divide between ‘externalism’ and ‘internalism’) should be traced back to the 1930s. In fact, the proposal of a Marxist-oriented historiography by the Soviet delegates at the International Congress of History of Science and Technology (London, 1931) led by Nikolai Bukharin, set off the ideological and methodological opposition that characterised the later years. Bukharin’s views on science are closely considered, as well as those of his Marxist critics, György Lukács and Antonio Gramsci. It is argued that, despite the fluidity of the positions of the 1920s and 1930s, these theories soon crystallized as demonstrated by the leftist reception of Bukharin’s and his associates’ perspective in the history of science, especially in Great Britain, as well as by the anti-communist reactions. Intellectualist approaches renouncing socio-economic factors, typically those by Alexandre Koyré and Thomas Kuhn, are reconsidered in the light of the ideological confrontation of the Cold War era. Reflection on the political-cultural embedding of the history of science has often been overshadowed by claims about the objectivity and neutrality of science and its historiography. Thus, the seminal discussion of the 1930s remains one of the most lucid moments of reflection about the role of science and history of science as cultural phenomena shaped by political struggles.
Opinion polling behind and across the Iron Curtain
Authors: Gieseke Jens
Published: December 2016

In the context of the Cold War, opinion polling as a method of observation stood for the shift from confrontation and clandestine preparations for a hot or cold civil war towards a competition between systems in the fields of political and cultural attractiveness and economic capabilities. Based on the cases of the West German polling institute Infratest and the East German Institute for Opinion Polling of the Socialist Unity Party, the article highlights the shifts in the external observation and internal self-observation of socialist society with respect to the change in epistemological approaches, research topics, patterns of construction of societal structures and the confluence between political expectations, professional self-understandings and impact on policy-making processes.
International construction of area studies in France during the Cold War
Authors: Popa Ioana
Published: December 2016

An Area Studies Division was created at the 6th Section of the École Pratique des Hautes Études (Paris) in the mid-1950s. It was devoted to several world regions, including the USSR and eastern Europe. This article investigates the links between its institutionalization and the international scientific and financial transfers underpinning it: the transatlantic support granted to the nascent division by the Rockefeller and Ford foundations and the academic cooperation programme that it launched with eastern Europe. The Russian, Soviet and East European programme served, thus, as an East/West interface and a platform for broader intellectual exchanges. Local French scientific, academic and political rationales favoured the specific pathways it took. The article also shows that the EPHE 6th Section was discreetly linked with American players in Cold War intellectual warfare whose forms of action gradually changed in the context of the thaw. In particular, it had connections with the Congress for Cultural Freedom. These collusions attest to the entanglement of scientific and political issues, their intricacies increasing when external factors compounded domestic ones.
The design of the floating baffle for Cassini tank and the analysis of restraining sloshing
Authors: Pan Kai , Li Xu , Fan Youhua , Cui Naigang
Published: December 2016

In this article, a new floating plate structure with “drive ring” is presented, which breaks the traditional idea of installing fixed baffle in a tank. In order to analyze the performance of this anti-sloshing structure, the effect of sloshing suppression and the liquid sloshing dynamics of this structure in a Cassni tank with numerical simulation is investigated. Liquid sloshing frequencies of the floating plate with different fill ratio under the circumstances of normal weight and micro-gravity were studied. At last aiming at the liquid sloshing amplitude, the suppression effect of the floating plate and rigid ring baffle was also studied under the circumstances of instantaneous angular and “Bang-Bang” transverse acceleration incentives with different fill ratios. The result of the numerical simulation shows that the movable-type floating plate structures can increase the liquid sloshing frequency and can effectively absorb the kinetic energy of the liquid sloshing and reduce liquid sloshing amplitude.