bluuebunny/crossref_metadata_2025 huggingface dataset:
Heavy Metals Contamination and Potential Health Risk Assessment of Ground Water: A Case Study of Open Dumpsites of KP, Pakistan
Authors: Khan Muhammad Ayaz , Khan Abdullah , Rahman Zia Ur , Naz Alia
Published: July 2024

This study was conducted to investigate heavy metal contamination and potential health risk of ground water of selected municipal solid waste (MSW) disposal sites of Khyber Pakhtunkhwa (KP) Pakistan. For this purpose a total of 30 composite samples of both surface and ground water were collected from dumpsites of Abbottabad, Bannu and Peshawar. The collected samples were analyzed for physico-chemical parameters and heavy metals by following standard methods. Results indicated that pH values were found within the acceptable limits specified by national environmental quality standards (NEQS) and world health organization (WHO). Mean concentrations of heavy metals were within NEQS and WHO limits, except for Ni which exceeded the NEQS and WHO limit of 0.02 mg/L in all samples, Similarly, Mn exceeded the limit set by NEQS and WHO (0.5 mg/L) in the ground water samples collected from Bannu dumpsite. The multivariate analysis indicated that the heavy metal contamination of the groundwater of the selected dumpsites was anthropogenic. The pollution index (PI) values (PI≥100) of Mn and Ni indicated very high pollution at individual levels while collectively based on heavy metals pollution index (HPI) values (HPI ≥ 200) the ground water of all the selected dumpsites were found highly polluted. Whereas, the hazard index (HI) values (HI ≥ 5) suggested adverse health effects. It was concluded that the ground water of all the dumpsites was highly polluted with heavy metals particularly Ni and Mn thus, posing a high health risk.
Advances in the Diagnosis of Atypical Polypoid Adenomyoma Through Next Generation Sequencing (NGS)
Authors: azua romeo Javier , Morón Sonia Bayona , Rodríguez Pérez Irene , angulo biedma Barbara
Published: July 2024

Atypical Polypoid Adenomyoma (APA) is a benign uterine lesion that occurs in women of reproductive age. The histological pattern is characterized by irregular epithelial proliferation and muscular stroma. Our work consists of a systematic review of the literature, including the description and analysis of a case study, and assesses the main immunohistochemical and molecular markers that contribute to making a differential diagnosis against endometrial adenocarcinoma. This allows offering patients conservative treatment compared to the radical management required for endometrial cancer, due to the significant physical and psychological consequences that one procedure or another can have on women's health. The goal of this research is to carry out an adequate diagnosis of APA by providing the necessary information to guide clinical management, establish patient prognosis, and minimize the emotional impact associated with the disease, all in combination with clinical and histopathological findings and complementary imaging tests. In conclusion, an appropriate immunohistochemical and molecular approach, along with the presumptive histological diagnosis, determine the correct classification of the lesion as APA and not as other malignant pathologies, which allows establishing a treatment protocol adjusted to the biological reality of this pathology.
The Impact of the Mining Facility on the Environment on the Example of the Křoví Quarry (Czech Republic)
Authors: Dahlmanns Anna , Kostecka Anna , Rerak Natalia , Sobczyk Wiktoria , Vundać Nika , Zakova Leona
Published: July 2024

The aim of the study was to assess the intensity of the impact of the Křoví mining facility on the environment. The impact of the exploitation of rock deposits in Křoví on the atmosphere, lithosphere, biosphere, hydrosphere and anthroposphere was presented. Vulnerability to natural hazards was also assessed. The multi-criteria Analytic Hierarchy Process (AHP) method and the Leopold matrix were used to assess the impact. The assessment of the impact of raw material extraction in the quarry was carried out by competent experts. It has been found that the lithosphere and biosphere are under the greatest pressure due to land use and surface transformation (including deforestation). The increased susceptibility of the area to natural hazards was noted due to vibrations caused by increased truck traffic (transportation of excavated material). The total value of the matrix indicates the average intensity of the mining facility's impact on the environment. The location of the deposit above the water table of the Bílý potok river means that the extraction of the mineral has a minor impact on the water conditions in the area. Changes in topography and vegetation, and soil degradation are temporary and reversible. Once the mining operations have ceased, the site should be reclaimed and the program of reforestation and habitat restoration implemented to help mitigate adverse impacts on the biosphere.
An Analysis of Decentralised Systems in Environment-Related Projects: Theoretical and Practical Perspective
Authors: Vaccargiu Matteo , Tonelli Roberto
Published: July 2024

The growing interest in environmental sustainability issues and, at the same time, the advantages offered by blockchain technology have strong connections between these two topics. This study explores the application of blockchain technology across various environmental domains, such as air quality, climate change impacts, and resource management. The research utilised a dual approach, combining a bibliometric analysis with VOSviewer and a topic analysis using BERT models to assess the discourse within both scientific literature extracted from Scopus and practical blockchain projects obtained from GitHub. The findings reveal that food security, energy, and sustainable agriculture are predominant topics in academic discussions, with a noticeable increase in focus from 2017 onwards. Practical projects are focused on transparent tracking and decentralised management. The overlap between academic and practical spheres is evident in the shared focus on energy and environmental management, demonstrating blockchain’s growing role in addressing global environmental challenges. The study underscores the importance of integrating theoretical research with practical implementations to harness blockchain’s full potential in promoting sustainable environmental practices.
Political Bias in AI-Language Models: A Comparative Analysis of ChatGPT-4, Perplexity, Google Gemini, and Claude
Authors: Choudhary Tavishi
Published: July 2024

Artificial intelligence (AI) driven language models have seen a rapid rise in development, deployment, and adoption over the last few years. This surge has sparked many discussions about their societal and political impact, including political bias. Bias is a crucial topic in the context of large models due to its far-reaching consequences on technology, politics, and society. It significantly influences public perception, decision-making, political discourse, and AI policy governance and ethics. This study investigates political bias through a comparative analysis of four prominent AI models: ChatGPT-4, Perplexity, Google Gemini, and Claude.Through a comprehensive analysis by systematically and categorically evaluating their responses to politically and ideologically charged tests and prompts, utilizing the Pew Research Center’s Political Typology Quiz, the Political Compass assessment, and ISideWith political party quiz, this study identifies significant ideological leanings and the nature of political bias within these models. The findings revealed that ChatGPT-4 and Claude exhibit a liberal bias, Perplexity is more conservative, while Google Gemini adopts more centrist stances. The presence of such biases underscores the critical need for transparency in AI development and the incorporation of diverse training datasets, regular audits, and user education to mitigate these biases. This analysis also advocates for more robust practices and comprehensive frameworks to assess and reduce political bias in AI, ensuring these technologies contribute positively to society and support informed, balanced, and inclusive public discourse, which will point towards neutrality.The results of this study add to the ongoing discourse about the ethical implications and development of AI models, highlighting the critical need to build trust and integrity in AI models. Additionally, future research directions have been outlined to explore and address the complex issue of bias in AI.
A Preliminary Observational Study of the Endoscopic Anatomical Structures of the Lumbar Spine Through the Foraminal and the Interlaminar Approach
Authors: Du Chuanchao , Song Kunfeng , Liu Xiaoguang , Zils Ulrich , Gore Satishchandra , Yang Jincai
Published: July 2024

Objective To explore the endoscopic anatomical structures of lumbar surgery. Methods A total of 290 patients who underwent lumbar endoscopic surgery due to lumbar intervertebral disc (IVD) herniation from September 2020 to September 2022 were retrospectively reviewed in our hospital,179 patients had complete surgical video recordings, including 108 males and 71 females, aged from 19 to 65 years, with an average age of 41±16 years. The endoscopic structures through the intervertebral foramen and interlaminar space were independently identified by 3 doctors with more than 3 years of related surgery experience. When there were differences of opinions, the three doctors would discuss and come to a consensus. The probability, location, and neighboring structures of each specific structures were statistically analyzed. Results The anatomical structures observed through the lumbar foramen under endoscopy include muscles and ligaments attached to the superior articular process (SAP), main blood vessels inside the intervertebral foramen, blood vessels on the surface of IVD, and blood vessels on the surface of the dural sac and nerve root. The major anatomical structures observed through interlaminar space are multifidus, the conjugated ligament of ligament flavum and capsule ligament (capsule part of flavum ligaments), edges of the lamina, specific vessel bundle to facet with exit nerve root. Conclusion The anatomical structures under spinal endoscopy have certain characteristics, which are grossly different from those under open surgery. Familiarity with these anatomical structures has important clinical significance.
Pulmonary Artery Obstruction Index, Biomarkers, and their Prognostic Value in Different Ethiologies of Pulmonary Embolism
Authors: Naum Alexandru Gratian , Jari Irina , Moisii Liliana , Ursu Andra Mara , Moisii Paloma
Published: July 2024

:. Background and Objectives: Pulmonary embolism, PE, incidence had been increasing in the last ten years. Computed thoracic pulmonary angiography, CTPA, had a major role in confirming PE di-agnosis.The main purpose of the study was to establish the prognostic value of a CTPA parameter: pulmonary artery obstruction index, PAOI, for PE risk assessment . A second objective of the re-search was to investigate the predictive accuracy of biomarkers (D-dimer, and cardiac Troponin T, c-TnT ), and PAOI, in 7-day mortality. The third objective of the study was the relationship between PAOI, and these biomarkers, in different etiologies of PE. Materials and Methods: The study com-prised 109 patients with PE, hospitalized, and treated between February 2021, and August 2022. They had different etiologies: deep vein thrombosis, DVT; persistent atrial fibrillation, AF; chronic obstructive pulmonary disease, COPD, exacerbation; Covid; and cancers. The investigations were the following: clinical examination; D-dimer testing, as a mandatory method for PE suspicion( values ≥ 500 µg/L were highly suggestive for PE); c-TnT , as a marker of myocardial injury(values ≥ 14 ng/L were abnormal); CTPA, with right ventricle dysfunction, RVD, signs, and PAOI. Treat-ments were according to PE risk: systemic thrombolysis (in high risk , and hemodynamic instability); low weight molecular heparins, LWMH, after systemic thrombolysis, or in high risk PE, with he-modynamic stability; direct oral anticoagulants, DOAC (in low, and intermediate risk). Results: The relationship PAOI- D-dimer, and PAOI- c-TnT, had very strong statistical correlation, for the entire sample, and for DVT, AF, COPD, Covid subgroups ( Rho = 0.815-0.982). PAOI had a high predic-tive accuracy for intermediate , and high risk together (area under curve, AUC=0.948), and high risk PE (AUC= 0.993). For 7-day mortality, D-dimer , and c-TnT had high predictive accura-cy(AUC=0.921, and 0.979). PAOI had statistical significance for 7-day mortality in Covid (p=0.045), and cancer (p=0.038) patients. Conclusions: PAOI was an important tool for PE risk as-sessment. D-dimer , and c-TnT were valuable predictors, for 7-day mortality in PE. PAOI, and D-dimer; PAOI, and c-TnT were strongly correlated, for the entire PE sample, and for DVT, AF, COPD, and Covid patients.
Dynamics of Cellulose Degradation by Soil Microorganisms from Two Contrasting Soil Types
Authors: Gladkov Grigory V. , Kimeklis Anastasiia K. , Orlova Olga V. , Lisina Tatiana O. , Kichko Arina A. , Bezlepsky Alexander D. , Andronov Evgeny E.
Published: July 2024

The search for active cellulolytic consortia among soil microorganisms is of significant applied interest, while the dynamics of the formation of such communities remain insufficiently studied. To gain insight into the formation of an active cellulolytic community, the experiment was designed to study the colonization of a sterile substrate (cellulose) by microorganisms from two soil types: sod-podzolic and chernozem. To achieve this, the substrate was placed in the soil and incubated for six months. To assess microbiome dynamics, the experiment employed sequencing of 16S rRNA and ITS2 amplicon libraries at four-time points. It was demonstrated that from the second month of the experiment, the prokaryotic component of the communities reached a state of stability, with a community composition that was specific to each soil type. The results demonstrated that there was no relationship between changes in community diversity and soil respiration. There also was no significant shift in community diversity throughout the chronosequence. Furthermore, the taxonomic composition of the community shifted towards a decrease in the proportion of Proteobacteria and an increase in representatives of the Bacteroidota, Bacillota, and Verrucomicrobiota phyla. The network analysis of the community demonstrated that, in contrast to sod-podzolic soil, chernozem is distinguished by a higher modularity, with the formation of taxon-specific groups of microorganisms at each stage of the chronoseries. These differences are attributed to alterations in the eukaryotic component of the community, particularly in the prevalence of nematodes and predatory fungi, which in turn influenced the cellulolytic community.
Clinical case of olfactory dysfunction in COVID-19 patients
Authors: Lukyanov А.V. ,   Central Research Institute of Epidemiology, the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation, Ploskireva А.А. ,   Central Research Institute of Epidemiology, the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation,   Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: July 2024

The olfactory dysfunction is one of the clinical manifestations of coronavirus infection. Unlike a decrease in the sense of smell, which can be observed with mucosal edema in influenza and other acute respiratory infections, with coronavirus infection, there is often a complete shutdown of the sense of smell – anosmia. This condition can be observed in patients not only in the acute period of infection, but also persist for a long time during the period of convalescence, which significantly reduces the quality of life of such patients. The presented clinical analysis shows, using examples from clinical practice, various variants of the influence of olfactory dysfunction disorders on the quality of life of patients and emphasizes the importance of the problem for the healthcare provider. Key words: coronavirus infection, anosmia, parosmia
Effectiveness of Activated Carbon from Jackfruit Skin for The Heavy Metal Lead (Pb) Adsorption Using The Langmuir and Freundlich Equations
Authors: Arke Nadya Ramadhani , Sari Dewa Ayu Made Dearwita , Dewati Retno
Published: July 2024

ABSTRACT. Activated carbon is a commonly used medium for adsorption to combat environmental pollution in both water and air. It is produced from plant or plantation waste containing carbon. Jackfruit skin, often considered as plantation waste, contains lignocellulosic compounds and has the potential to be used as active carbon. Activated carbon from jackfruit skin has a good absorption capacity and can absorb heavy metal waste such as lead (Pb). A recent study aimed to evaluate the absorption effectiveness of active carbon from jackfruit skin. The process involved making activated carbon using the pyrolysis method, and then analyzing its lead absorption capacity in lead nitrate solution by varying the weight of the activated carbon (10g, 15g, 20g, 25g, 30g) and the adsorption time in minutes (40, 60, 80, 100, 120). The levels of absorbed lead on activated carbon were tested using Atomic Absorption Spectrophotometry (AAS) at a wavelength of 283.3 nm. The research findings indicate that the effectiveness of activated carbon absorption reaches 99%, and the appropriate equation model for the adsorption process is the Freundlich isotherm, indicating a multilayer adsorption process.

Keywords:

Adsorption Isotherm, Activated Carbon Jackfruit Skin, Lead (Pb)
Methods of recovery of centrifugal water pump resources
Authors: Yuldashev Sh. U. , Sharypov Z. Sh.
Published: July 2024

In the article presents the results of researches of the device of centrifugal pumps of type «D», operating conditions of pumps, processes of deterioration of details, factors infiuencing occurrence of defects in details, moderning of technology of restoration of a  resource of detalis of water pumps. A combined method for restoring the resource of the casing is proposed, taking into account the resurts of researches of wear of the working surface and working conditice hudro abrasive, cavitations,hudrogen and other types of wear. Recommendations are qiven to the choice of processing and taking into account the infiuence of technological and operational factors on the adhesive strength of the joint of the massing.  Figs.: 17. Tabl. 3. Refs.: 10 titles.
Synthesis of the physical neural terms and long short-hour memory for detection of prophylerative retinopathies
Authors: Prochukhan Dmytro
Published: July 2024

The effectiveness of a combination of hypopharyngeal neural measures and long-term short-hour memory in the diagnosis of profilerative retinopathy has been studied. The methods of synthesis of the indicated types of measures are examined. The advantages of the vicorsynthetic neural network ResNeXt-101 have been established using ResNet-101. A neural boundary model has been developed that synthesizes the indicated boundary with the dimension of long-term short-term memory. The model was developed. Indicated by the functioning mechanisms of the specified model. Behind this additional fragmented model is the task of detecting profilerative retinopathy. High indicators of classification accuracy were obtained. Figs.: 3.Tabl.: 2. Refs.: 14 titles.
A neural network for recognizing and classifying images at the boundaries of several classes
Authors: Dmitrienko Valerii , Leonov Sergey , Mezentsev Mykola
Published: July 2024

The neural network belongs to the computer systems of computing technology and artificial intelligence in the field of building automated systems for recognizing and classifying images at the border of several classes, which is made with the ability to perform diagnostics and image recognition at the borders of two, three or more classes due to the fact that the layer schemes for selection of one, two or more single signals from the outputs of the layer of output neurons , , ¼, , ¼,    . at each moment of time remembers the number of non-zero signals at the output of neurons of the output layer, and the second layer of output neurons  , , ¼, , ¼,  remembers neurons of the output layer that have non-zero signals at their outputs. The technical result achieved by this neural network is an increase in the number of classes that can be recognized and the ability to recognize images that are at the same Hamming distance from two, three or more reference images stored in the connection weights of the neurons of the memory layer. haunting An experimental evaluation of the method and neural network for solving the problems of matching digital images was carried out. The neural network is implemented as a software utility  Il.: 2; Bibliogr.: 15 titles.
Integrating advanced human-computer interaction and machine learning models for optimizing VR systems in educational and business applications
Authors: Tao Li , Honcharenko Tetyana
Published: July 2024

This paper presents the development of an advanced Human-Computer Interaction (HCI) model and algorithm integrating Natural Language Processing (NLP) to optimize Virtual Reality (VR) systems for educational and business applications. The proposed model enhances user experience and operational efficiency by addressing interface design, user engagement, real-time data processing, and accessibility. Continuous learning and contextual data integration ensure adaptive and personalized interactions, improving the functionality and applicability of VR environments. Fig.: 2. Refs.: 11 titles.
Anthropology after metaphysicsin the philosophy of Bruno Latour
Authors: Petrikovskaya Elena ,   RAS Institute of Philosophy
Published: July 2024

Under the influence of science, technology and global changes, the pathos of caring for a person today is transferred to non-human communities. Sensitivity to matter and its changing states has returned to philosophy. Nature is again considered as a universal model of everything that exists. A new value has become the world in all its diversity, the world itself, unlimited by the phenomenon of man. To think in a new way is to think on the other side of a person, to abandon the idea that it is a person who thinks. This is the anthropological trend in modern philosophy. It remains to consider what are the consequences of overcoming anthropocentrism and “posthumanistic” decisions for the individual, culture, and humanities. And why, despite the struggle with the “anthropological dream” (M.Foucault), the anthropological method of research remains in demand. To this end, the author refers to the works of the French philosopher, anthropologist, sociologist of science Bruno Latour to characterize his anthropological project. The author records when solving which issues Latour turns to anthropology. The place of anthropology in the actor-network theory of the philosopher is discussed. It shows the consonance of Latour’s methodological approach to the branch of philosophical anthropology that comes from Н.Plessner and A.Gehlen, in which there is no isolation of either the field of knowledge itself or its subject. On the contrary, philosophical and anthropological reflection is motivated by pragmatics, by what is carried out beyond the boundaries of philosophy and pure consciousness. The refusal to build anthropology on the basis of New European rationalism gives a new breath to the anthropological approach. There is a search for an alternative framework of thinking to anthropocentrism, new foundations from which the position of a person in the world, human reality can be comprehended. An overview of ideas regarding the “anthropology of modern” is given, the purpose of which is to explain to the bearers of modern consciousness that their own actions diverge from their own words. The study of Bruno Latour’s anthropological reflection contributes both to the concretization of the theoretical and methodological foundations of his philosophy and to the clarification of the question of the goals of philosophical anthropology. By publishing this text, the author invites colleagues to discuss the strategies of modern philosophical and anthropological discourse.
Paradoxes of modern humanism
Authors: Gurevich Pavel
Published: July 2024

Perhaps no social topic contains as many contradictions as humanism. And everytime, in one era or another, the paradoxical nature of the problem of humanity re-veals itself from an unexpected side. It is not perceived as an unforeseen situa-tion when humanism is painted in misanthropic tones. There is no particular concernabout the situation when humanism turns out to be a simulacrum and in its essence ex-presses an ordinary emptiness. In various arrangements of humanism, we are talking about the cult of man, but manhimself is seen as an evil, destructive creature. They talk about the inevitability of hu-manity, but paradoxically they put race, ethnicity and other social formations insteadofa person. Abstract and concrete humanism are distinguished, but a real person findshimself in the chains of totalitarianism. Ordinary crimes are covered up with humanis-tic rhetoric.The author of the article reflects on the paradoxes that are revealed upon closer exami-nation of this concept.
Fichas terminológicas apresentadas para o registro multilíngue de sinais-termo nas áreas de Biossegurança e Saúde
Authors: Francisco Gildete da S. Amorim , Machado Vanessa Lima Vidal , Castro Júnior Gláucio de
Published: July 2024

Esta pesquisa tem como objetivo apresentar o Glossário Multilíngue Ilustrado e Terminológico em realidade aumentada nas áreas de biossegurança e saúde. O processo de elaboração contou com análise documental para seleção e coleta dos sinais, seguido da contribuição de pesquisadores e pessoas surdas de diferentes instituições no processo de validação. Foram apresentadas reflexões importantes quanto à precariedade da acessibilidade de informações no período de pandemia de covid-19. Por meio das fichas terminológicas, obteve-se um material em quatro línguas de sinais: Língua de Sinais Brasileira (Libras), Língua de Sinais Americana (ASL), Língua de Sinais Chilena (LSCh) e Língua de Sinais Argentina (LSA), também divulgado no formato on-line de modo aberto e gratuito, contendo 98 sinais-termo em Libras, 44 em ASL, 97 em LSCh e 94 em LSA, perfazendo uma rica produção em línguas de sinais. A relevância do material está em permitir esclarecer à Comunidade Surda as informações que circularam durante a pandemia, apresentando potencial contribuição para o ensino e a divulgação da biossegurança, saúde e das ciências biológicas em língua de sinais.
Discursos de formadores de professores de línguas estrangeiras sobre a pandemia: questões identitárias e emocionais
Authors: Figueiredo Eduardo Henrique Diniz de , Kluge Denise , Stürmer Helena , Finardi Kyria
Published: July 2024

O presente artigo traz resultados de um estudo que teve como objetivo investigar os discursos de formadores/as de professores/as de línguas estrangeiras acerca da pandemia de COVID-19 e de seus efeitos identitários e emocionais nos contextos onde atuam. A pesquisa foi realizada em duas universidades públicas federais, uma no sul e a outra no sudeste do Brasil, através de questionários e entrevistas semi-estruturadas. Os resultados mostram que os discursos construídos pelos/as participantes atuam de duas formas: a) em alguns momentos, enfatizam a agência que a pandemia exerceu sobre a comunidade acadêmica; b) em outras ocasiões, dão destaque às possibilidades de agência desta comunidade em vista das dificuldades impostas pela crise sanitária. Tais resultados apontam para a necessidade de reflexões sobre como romper com práticas naturalizadas durante a pandemia e, ao mesmo tempo, ressignificar práticas de ensino-aprendizagem de línguas a partir do que foi aprendido durante o isolamento social. O papel dos Estudos Linguíticos nesse processo é explorado e discutido, principalmente no que diz respeito: a) à necessidade de escutar as narrativas de docentes e discentes sobre suas experiências durante e depois da pandemia; b) à importância de refletir sobre outras formas de atuar dentro do contexto acadêmico, principalmente com maior atenção a questões emocionais; c) às possibilidades de ressignificar o que se entende por educação on-line e híbrida.
O fenômeno da neologia no domínio da Moda em meio à pandemia da covid-19
Authors: Castorino Pauler , Alves Ieda Maria
Published: July 2024

Analisamos, neste artigo, a renovação terminológica da Moda frente à pandemia do novo coronavírus; especificamente, investigamos o campo dos vestuários, observando se surgiram novas designações que confluam com o período em pauta e, caso ocorram, por quais processos foram formadas. Pautar-nos-emos nos estudos lexicais, sobretudo na Terminologia (Ciência do Léxico que tem como objeto o léxico especializado) e na Neologia (disciplina que tem como foco a inovação lexical). Dessa maneira, basear-nos-emos em Cabré (2009), Krieger (2006), Rondeau (1984) e mais. O método empregado é fundamentado nos postulados de Almeida (2006) – sobre como seguir os parâmetros da Teoria Comunicativa da Terminologia (TCT) – e de Cabré (1999); simultaneamente, para verificarmos o status neológico das unidades terminológicas inventariadas, consultamos Boulanger (1979). O corpus deste trabalho é composto por matérias retiradas das seções de Moda das versões brasileiras dos periódicos Glamour, Harper’s Bazaar, L’Officiel e Vogue, extraídas entre janeiro de 2020 e dezembro de 2021. Os resultados encontrados demonstram que houve alteração terminológica na Moda no período da pandemia, principalmente por intermédio de composições sintagmáticas e estrangeirismos; observamos, ainda, que essas formações fazem uso de termos advindos de outras áreas, por exemplo, da Medicina, da Virologia e outras.
Atenção Conjunta em sala de aula no Ensino Remoto Emergencial: interações com criança surda
Authors: Sousa de Sena Fábia , Cavalcante Marianne Carvalho Bezerra , Carvalho Lyedja Syméa Ferreira Barros
Published: July 2024

O objetivo deste artigo é analisar os elementos multimodais (McNeill, 2003) que dão sustentação às cenas de Atenção Conjunta no contexto de dois sistemas linguísticos distintos (Libras e Língua Portuguesa), em contexto virtual. A metodologia foi conduzida com base nos pressupostos teórico-metodológicos de pesquisa qualitativa e quantitativa de natureza interpretativista e como instrumento para o alcance do objetivo proposto. O lócus da pesquisa se deu na sala de aula remota de uma escola do município de João Pessoa-PB. Participaram da pesquisa uma criança surda com oito anos de idade, uma professora de sala regular do 3º ano do Ensino Fundamental Anos Iniciais; e dois intérpretes de Libras. Realizamos observações em sala de aula remota que ocorreu via Google Meet. Os resultados obtidos apontam o direcionamento do olhar como elemento de maior ocorrência, destacando a relevância desse elemento para a realização da interação em virtude da condição linguística visual do sujeito surdo e a recorrência do gesto de apontar; depreendeu-se, também, a relevância de se compreender o entrelace das produções multimodais nesses dois sistemas linguísticos. Por fim, destacamos a Atenção Conjunta como uma importante estratégia desenvolvida pelos intérpretes e/ou professora para o estabelecimento da interação com as crianças surdas.
O que é que o online tem? A mediação no Teletandem em tempos pandêmicos
Authors: Salomão Ana Cristina Biondo , Piai Lais
Published: July 2024

A presente investigação, desenvolvida no contexto telecolaborativo do Teletandem Brasil: línguas estrangeiras para todos (Telles, 2009), visou verificar de que maneira as sessões de mediação são estruturadas e gerenciadas, via plataformas de videoconferência. As mediações são sessões de assistência pedagógica realizadas com os participantes brasileiros após as interações na língua-alvo e que, a partir da pandemia da COVID-19, se tornaram totalmente on-line. Essa pesquisa considera os resultados de Sartori (2021), que, ao investigar a mediação presencial, localizou, por meio dos dados analisados sob a perspectiva da Análise da Conversação (AC), seis categorias que estruturam essa modalidade, sendo elas: abertura da mediação; desenvolvimento da mediação e uso de marcadores verbais; fechamento da mediação; sobreposição de vozes ou falas simultâneas; pares adjacentes; e riso. Por meio de uma pesquisa qualitativa, realizada no âmbito do Teletandem desenvolvido na Unesp de Araraquara (FCLAr), utilizando questionário inicial, gravação das sessões de mediação realizadas pelo Google Meet e relato reflexivo das mediadoras acerca das mediações publicado na Comunidade de Prática do Teletandem Araraquara, investigamos as possíveis semelhanças e diferenças entre a mediação nos formatos presencial e on-line. As participantes da pesquisa foram duas mediadoras que conduziram turmas diferentes. A partir da análise das mediações à luz da AC, verificou-se que as categorias organizadoras propostas por Sartori (2021) são encontradas na mediação on-line, mas surge, também, a categoria das pausas e silêncios. Ainda, foi possível averiguar diferenças substanciais no que concerne aos marcadores conversacionais não-verbais. Conclui-se que a mediação on-line exige diferentes habilidades nos processos de planejamento e gerenciamento, pois, embora se aproxime da mediação presencial e atinja os objetivos previstos, ela é modificada pelas diferentes formas de interação entre os participantes no contexto digital.
Emoções e desigualdade de gênero em narrativas de professoras durante a pandemia
Authors: Guedes Marise Rodrigues , Aragão Rodrigo Camargo , Alomba Ribeiro Maria D'Ajuda
Published: July 2024

A fusão entre o tempo e o espaço dedicados ao exercício profissional e às tarefas domésticas sobrecarregaram ainda mais as mulheres professoras na pandemia da covid-19. Diante desse contexto, este estudo avalia como a experiência de ensino pandêmico pode ter retroalimentado a estrutura patriarcal presente nas desigualdades de gênero no contexto do ensino. A discussão é feita à luz da compreensão sobre o papel conjugado da linguagem e das emoções na atividade reflexiva das docentes, suscitada por protocolos de Pesquisa Narrativa. Para análise, utilizou-se os procedimentos da Análise de Conteúdo. Aqui, indica-se como um determinado emocionar e linguajar se apresentam no conteúdo das narrativas das docentes, ao mesmo tempo em que retroalimentam a cultura patriarcal, na qual as relações de desigualdade de gênero estão fundamentadas. Os resultados apontam para emoções de frustração, autocobrança, ansiedade e autodepreciação em um crescente contexto de desumanização circunscrito em conversações autodepreciativas e do dever ser que forjam a noção da improdutividade feminina. Dessa maneira, o estudo demonstra como o modo de funcionar patriarcal, durante a pandemia, aprofundou a fragilização das mulheres professoras participantes deste estudo.
Intercâmbio virtual em tempos pandêmicos: perspectivas de Teletandem autônomo
Authors: Oliveira Victor César de , Ávila Ariadne Beatriz , Zakir Maisa de Alcântara , Messias Rozana Aparecida Lopes
Published: July 2024

As práticas oportunizadas por intercâmbios virtuais (O’Dowd, 2018) têm proporcionado contextos profícuos no que diz respeito ao ensino e aprendizagem de línguas estrangeiras. No âmbito dos estudos telecolaborativos, atuamos, especificamente, com as práticas de Teletandem (Telles; Vassallo, 2006, 2009, 2015), um ambiente de interações on-line e bilíngues que promove a troca linguística e cultural entre duas pessoas de países distintos. O presente trabalho, por meio de uma análise interpretativa de base qualitativa (Lüdke; André, 2013), enfoca relatos de participantes brasileiros sobre suas experiências com as interações on-line e seus efeitos em tempos pandêmicos, durante o primeiro semestre de 2020. Os dados coletados evidenciaram que as práticas telecolaborativas, além de maximizar o processo de ensino/aprendizagem e promover trocas interculturais, possibilitaram aos interagentes estabelecer contato afetivo, pelo fato de ocorrerem virtualmente, durante o isolamento social.
Genome-wide meta-analyses of cross substance use disorders in European, African, and Latino ancestry populations
Authors: Lai Dongbing , Zhang Michael , Green Nick , Abreu Marco , Schwantes-An Tae-Hwi , Parker Clarissa , Zhang Shanshan , Jin Fulai , Sun Anna , Zhang Pengyue , Edenberg Howard , Liu Yunlong , Foroud Tatiana
Published: July 2024

Genetic risks for substance use disorders (SUDs) are due to both SUD-specific and SUD-shared genes. We performed the largest multivariate analyses to date to search for SUD-shared genes using samples of European (EA), African (AA), and Latino (LA) ancestries. By focusing on variants having cross-SUD and cross-ancestry concordant effects, we identified 45 loci. Through gene-based analyses, gene mapping, and gene prioritization, we identified 250 SUD-shared genes. These genes are highly expressed in amygdala, cortex, hippocampus, hypothalamus, and thalamus, primarily in neuronal cells. Cross-SUD concordant variants explained ~ 50% of the heritability of each SUD in EA. The top 5% individuals having the highest polygenic scores were approximately twice as likely to have SUDs as others in EA and LA. Polygenic scores had higher predictability in females than in males in EA. Using real-world data, we identified five drugs targeting identified SUD-shared genes that may be repurposed to treat SUDs.
Study protocol for a stepped-wedge implementation study investigating the intersectoral collaboration of implementering the TREAT INTERACT intervention for primary school teachers and the mhGAP for health care workers for child mental health promotion in Uganda
Authors: Skar Ane-Marthe Solheim , Engebretsen Ingunn Marie S. , Braathu Nora , Aber Harriet , Bækkelund Harald , Kühl Melf-Jakob , Mukisa Majorie , Nalugya Joyce Sserunjogi , Skokauskas Norbert , Skylstad Vilde , Wentzel-Larsen Tore , Babirye Juliet Ndimwibo
Published: July 2024

Background
Mental and neuropsychological disorders make up approximately 14% of the total health burden globally, with 80% of the affected living in low- and middle-income countries (LMICs) of whom 90% cannot access mental health services. The main objective of the TREAT INTERACT study is to adapt, implement, and evaluate the impact of a novel, intersectoral approach to prevent, identify, refer, and treat mental health problems in children through a user centered task-sharing implementation of the TREAT INTERACT intervention, inspired by the World Health Organization (WHO) Mental Health Gap Action Programme Intervention Guide (mhGAP-IG) for primary school staff in Mbale, Uganda.
Methods
This is a pragmatic mixed-methods hybrid Type II implementation-effectiveness study utilizing a co-design approach. The main study utilize a stepped-wedged trial design with six starting sequences, randomizing three schools to the intervention at each interval, while the remaining act as “controls”. Other designs include a nested prospective cohort study, case control studies, cross-sectional studies, and qualitative research. Main participants’ outcomes include teachers´ mental health literacy, stigma and violence towards the school children. Implementation outcomes include detection, reach, sustainability and service delivery. Child and caregiver outcomes include mental health, mental health literacy, and help-seeking behavior.
Discussion
Based on the results, we will develop sustainable and scalable implementation advice and draft implementation guidelines in line with current WHO guidelines. This project will generate new knowledge on the structure, organisation, delivery, and costs of mental health services in a LMIC setting, as well as new knowledge on the implementation and delivery of new health services.
Trial registration
ClinicalTrials, NCT06275672, 28.12.2023, retrospectively registered.
Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites
Authors: Simon Marie-Christine , Klümpen Linda , Mantri Aakash , Philipps Maren , Seel Waldemar , Stoffel-Wagner Birgit , Coenen Martin , Weinhold Leonie , Hasenauer Jan , Stehle Peter
Published: July 2024

Oats have various positive effects on human health, but the underlying mechanisms are not fully understood. To determine the oat-microbiome-host interactions that contribute to metabolic improvements, we conducted a randomized, short-term dietary intervention with high-dose oat intake in individuals with metabolic syndrome (DRKS00022169). Thirty-two participants completed the trial. We find that the two-day oat diet improves lipid metabolism by lowering serum total cholesterol by 8 % and low-density lipoprotein cholesterol by 10 %, accompanied by distinct changes in plasma and fecal metabolomic profiles and gut microbiota. These induced alterations, particularly an increase in microbially produced phenolic compounds, correlate inversely with changes in cholesterol levels, suggesting that plasma phenolic compounds are driving factors for the cholesterol-lowering effect of oats, besides the known mechanisms of β-glucan. This newly identified mechanism might be of great potential since a short-term, high-dose oat diet is a suitable and rapid approach to alleviate obesity-related lipid disorders.
Glaucoma Rehabilitation using ElectricAI Transcranial Stimulation (GREAT) – Study Protocol for Randomized Controlled Trial using Combined Perceptual Learning and Transcranial Electrical Stimulation for Vision Enhancement
Authors: Jia Shuwen , Mei Xiaolin , Chen Lilin , Chan Lok Hin , Tsang Celia , Suen Venus , Li Tingni , Zaw Myo Win , Liu Amanda , Thompson Ben , Sabel Bernhard , Woo George , Leung Christopher K.S. , Yip Shea-ping , Chang Dorita H. F. , Cheong Allen M.Y.
Published: July 2024

Background:
Glaucoma patients with irreversible visual field loss often experience decreased quality of life, impaired mobility, and mental health challenges. Perceptual learning (PL) and transcranial electrical stimulation (tES) have emerged as promising interventions for vision rehabilitation, showing potential in restoring residual visual functions. The Glaucoma Rehabilitation using ElectricAI Transcranial stimulation (GREAT) project aims to investigate whether combining PL and tES is more effective than using either method alone in maximizing the visual function of glaucoma patients. Additionally, the study will assess the impact of these interventions on brain neural activity, blood biomarkers, mobility, mental health, quality of life, and fear of falling.
Methods:
The study employs a three-arm, double-blind, randomized, superiority-controlled design. Participants are randomly allocated in a 1:1:1 ratio to one of three groups receiving: (1) real PL and real tES (2) real PL and sham tES, and (3) placebo PL and sham tES. Each participant undergoes 10 sessions per block (~ 1 hour each), with a total of three blocks. Assessments are conducted at six time points: baseline, interim 1, interim 2, post-intervention, 1-month post-intervention, and 2-month post-intervention. The primary outcome is the mean deviation of the 24 − 2 visual field measured by the Humphrey Visual Field Analyzer. Secondary outcomes include detection rate in the suprathreshold visual field, balance and gait functions, and electrophysiological and biological responses. This study also investigates changes in neurotransmitter metabolism, biomarkers, self-perceived quality of life, and psychological status before and after the intervention.
Discussion:
The GREAT project is the first study to assess the effectiveness of PL and tES in the rehabilitation of glaucoma. Our findings will offer comprehensive assessments of the impact of these treatments on a wide range of brain and vision-related metrics including visual field, neural activity, biomarkers, mobility, mental health, fear of falling and quality of life.
Trial registration:
ClinicalTrials.gov NCT05874258. Registered on 15th May 2023
URL: https://clinicaltrials.gov/study/NCT05874258?cond=NCT05874258&rank=1
The feasibility and safety of ultrasound-guided puncture for treatment of septic arthritis in children
Authors: Michaud Jeffrey , Dutron Sarah , Pico Julien , Jeandel Clément , Joly-Monrigal Pauline , Neagoe Petre , Alkar Fanny , Sarradin Thomas , Domitien Léa , Prodhomme Olivier , Jeziorski Eric , DELPONT Marion
Published: July 2024

Background We wanted to know whether treating septic arthritis in children was feasible and safe under ultrasound (US) guidance.
Methods We retrospectively included 67 children (mean age, 3.0 years; range: 1 month–12 years) treated for septic arthritis of the hip, shoulder, or ankle using arthrocentesis or arthrotomy under US or fluoroscopic guidance (non-US group) with at least two years of follow-up.
Results We found no significant difference between the groups. Three puncture failures required arthrotomy (two under US guidance). Three patients required early revision surgery: one had undergone arthrocentesis with US, one arthrocentesis without US, and one arthrotomy without US. At the last follow-up, there were no clinical sequelae but two hip arthrotomies (one US and one non-US child) showed asymptomatic calcifications.
Conclusions US guidance is feasible and safe for treating septic arthritis in children, visualizing structures not shown by X-rays and avoiding radiation exposure during surgery.
Trial registration IRB-MTP_2021_05_202100781
Level of evidence: IV (case series)
Change in the concentration of pollutants in the air over the city of Lucknow, together with HYSPLIT4.0's trajectory and dispersion analysis
Authors: Kumar Vipin , Patel Prabhat Kumar
Published: July 2024

This study examines the mean daily concentrations of oxides of carbon (CO), sulphur dioxide (SO2), nitrogen dioxide (NO2), and respirable suspended particles (RSPM-PM10) at seven monitoring stations in Lucknow city: Hazratganj, Gomti Nagar, Talkatora, Aliganj, Sarai Mali Khan, Mahanagar, and Ansal TC. The data is collected between 2016 and 2022. Based on the analysis, it can be observed that at all locations, the yearly average concentration of RSPM varies between 148.74 and 323.05 µg m-3, SO2 between 7.11 and 8.94 µg m-3, NO2 between 23.52 and 31.86 µg m-3, and CO between 27.38 and 33.89 µg m-3. The study of seasonal variation reveals that the lowest recorded concentration of RSPM was 81.59 µg m-3 during the monsoon, while the highest recorded concentration was 447.47 µg m-3 during the post-monsoon. On the other hand, seasonal variations in SO2 and NO2 were found to be below the recommended requirements, ranging from 5.55 to 10.94 µg m-3 and 20.23 to 38.40 µg m-3, respectively. The COVID-19 lockout in 2020 caused the pollution level to somewhat decline, but it did not fall below the recommended limit for CO and RSPM. The Indian government has banned factories and implemented various measures within the city, but the levels of CO and PM10 in Lucknow are not decreasing. The Trajectory and Dispersion study of the HYSPLIT4.0 model indicates that the wind, which blows from the northwest, carries pollutants from close by areas to maintain daily pollution levels above the Central Pollution Control Board's guidelines (i.e., 100 µg m-3). This suggests that there is insufficient local pollution control. The results suggest that controlling particulate matter and carbon monoxide pollution in the city is a serious challenge and has an alarming situation as compared to SO2 and NO2 pollutants.