bluuebunny/crossref_metadata_2025 huggingface dataset:
Pathogens, patterns of pneumonia, and epidemiologic risk factors associated with respiratory disease in recently weaned cattle in Ireland
Authors: Murray Gerard M. , More Simon J. , Sammin Dónal , Casey Mìcheàl J. , McElroy Máire C. , O’Neill Rónan G. , Byrne William J. , Earley Bernadette , Clegg Tracy A. , Ball Hywel , Bell Colin J. , Cassidy Joseph P.
Published: January 2017

We examined the pathogens, morphologic patterns, and risk factors associated with bovine respiratory disease (BRD) in 136 recently weaned cattle (“weanlings”), 6–12 mo of age, that were submitted for postmortem examination to regional veterinary laboratories in Ireland. A standardized sampling protocol included routine microbiologic investigations as well as polymerase chain reaction and immunohistochemistry. Lungs with histologic lesions were categorized into 1 of 5 morphologic patterns of pneumonia. Fibrinosuppurative bronchopneumonia (49%) and interstitial pneumonia (48%) were the morphologic patterns recorded most frequently. The various morphologic patterns of pulmonary lesions suggest the involvement of variable combinations of initiating and compounding infectious agents that hindered any simple classification of the etiopathogenesis of the pneumonias. Dual infections were detected in 58% of lungs, with Mannheimia haemolytica and Histophilus somni most frequently recorded in concert. M. haemolytica (43%) was the most frequently detected respiratory pathogen; H. somni was also shown to be frequently implicated in pneumonia in this age group of cattle. Bovine parainfluenza virus 3 (BPIV-3) and Bovine respiratory syncytial virus (16% each) were the viral agents detected most frequently. Potential respiratory pathogens (particularly Pasteurella multocida, BPIV-3, and H. somni) were frequently detected (64%) in lungs that had neither gross nor histologic pulmonary lesions, raising questions regarding their role in the pathogenesis of BRD. The breadth of respiratory pathogens detected in bovine lungs by various detection methods highlights the diagnostic value of parallel analyses in respiratory disease postmortem investigation.
Creep and damage of an adhesive anchor system by accelerated testing and modeling
Authors: Yang Lingqi , Chen Fangliang , Yin Huiming
Published: January 2017

An accelerated testing and modeling method was proposed and implemented to predict the long-term performance through short-term pullout tests of a cylindrical anchor core by tensile loading at different elevated testing temperatures. Dimensional analysis was conducted to predict the creep behavior of adhesive anchor systems by small-scale tests. By using the frequency-temperature superposition principle, the master curves of the complex and storage moduli were generated in the Prony series form. By performing inverse numerical Laplace transformation, the creep compliance of the adhesive in the time domain was calculated and then used in the viscoelastic analysis of the adhesive anchor system. To validate the model, six adhesive anchor samples with different sizes of hole diameter and depth were fabricated and creep tests were then conducted at different temperatures. Overall, the test results agree well with the theoretical ones using the adhesive’s viscoelastic properties. An accelerated test protocol was further established for the long-term performance analysis of the adhesive anchor systems. The error sources of the experiments were discussed. Because of the generality of the formulation and testing mechanism, the present test method is applicable to the design and analysis of different types and sizes of adhesive anchor systems.
Hierarchical multiscale simulations of crystalline β-octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (β-HMX): Generalized interpolation material point method simulations of brittle fracture using an elastodamage model derived from molecular dynamics
Authors: Jiang Shan , Tao Jun , Sewell Thomas D , Chen Zhen
Published: January 2017

A predictive constitutive model for single-crystal β-octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (β-HMX) under simple loading conditions was developed using a hierarchical multiscale approach based on molecular dynamics and the generalized interpolation material point method. Basic mechanical behaviors, such as elastic and damage responses to external loading conditions, were predicted at the molecular level using molecular dynamics. The molecular dynamics results were used to construct a preliminary elastodamage model for the generalized interpolation material point (GIMP) simulations. Anisotropy of the β-HMX crystal, which affects the secant elastodamage stiffness tensor in the constitutive model, was taken into account. The GIMP method was used to deal with large deformation and fracture. GIMP results predicted using the hierarchically obtained elastodamage model are shown to be in close agreement with the molecular dynamics predictions. Although the evolution of local damage surfaces from GIMP is not as detailed as that from molecular dynamics, the main features of nonlinear elastodamage in the stress–strain relationship are captured by GIMP at reduced computational expense. Thus, this preliminary hierarchical multiscale procedure can be considered as useful for simulations of elastodamage behaviors in brittle materials for engineering purposes.
Psychometric Evaluation of a New Instrument to Evaluate School Nurses’ Perceptions on Concussion Care Management
Authors: Schneider Kathleen H.
Published: January 2017

The rate of concussions in adolescents has risen over the last decade, resulting in cognitive and emotional problems. Neurologists recommend cognitive and physical rest during the recovery period, followed by a transitional return-to-classroom protocol. The purpose of the study was to develop and test an instrument that explores the beliefs and roles of school nurses in concussion care management. The instrument was a cross-sectional descriptive survey based on the theory of planned behavior, using Qualtrics®. The psychometric properties of the instrument were assessed through exploratory factor analysis with orthogonal rotation. The reliability of the instrument was assessed for internal consistency reliability using Cronbach’s α. Kaiser–Meyer–Olkin for sample adequacy was .8; Cronbach’s α strong (.851).
Toxic Epidermal Necrolysis Possibly Linked to Aztreonam in Bone Marrow Transplant Patients
Authors: McDonald Brendan J. , Singer Jack W. , Bianco James A.
Published: January 2017

OBJECTIVE AND SETTING:

After instituting aztreonam as part of antibiotic prophylaxis in bone marrow transplant (BMT) patients at the Seattle Department of Veterans Affairs Medical Center, the first two cases of toxic epidermal necrolysis (TEN) occurred in more than 250 BMT patients at this center. We have examined the possible cause-and-effect relationship between aztreonam and TEN.

PATIENTS:

The first patient was a 23-year-old man with acute lymphocytic leukemia receiving a BMT from a related mismatched donor. He experienced profound conjunctivitis and superficial bulla covering 60 percent of his body surface area (BSA). The second patient, a 32-year-old man with lymphoma, received a BMT from a matched unrelated donor. He exhibited lymphocytosis, acute conjunctivitis, and bullous lesions covering 60 percent of his BSA.

INTERVENTIONS:

Aztreonam was discontinued in both patients. The first patient was treated with pigskin grafting and the second was treated with topical silver sulfadiazine.

RESULTS:

Despite stabilization of symptoms, both patients eventually died of infectious complications.

CONCLUSIONS:

Histological data in both patients were more consistent with TEN than graft-versus-host disease (GVHD) in that dermal infiltrates were sparse or absent. The onset of cutaneous symptoms was of more acute onset than acute GVHD, and ocular complaints are uncommon in acute GVHD. Furthermore, the onset of TEN bore a closer temporal relationship to aztreonam than to other drugs administered.