bluuebunny/crossref_metadata_2025 huggingface dataset:
Simple, Rapid, and Highly Sensitive Magnetic Beads ELISA for Detection of SARS CoV-2 Antibodies (IgG) in Human Plasma Samples as a Point of Care Assay
Authors: Bhatia S.
Published: December 2023

The pandemic outbreak of coronavirus (SARS CoV-2) has been going on over the last 3 years. The people are vaccinated with different vaccines targeting the S protein. Aim. Therefore, it is essential to have an assay that can detect different parts of the virus as a serological assay and can be performed as a point of care test. Hence, in this work, we decided to develop such an assay with the help of magnetic beads. Methods. The magnetic beads ELISA (MB ELISA) was developed in a microtube. The viral ligand-specific magnetic beads were used to detect the nucleoprotein (NP)-specific IgG antibodies in human plasma samples. The results were read with the naked eye as well as with professional ELISA readers. Results. 7 μL magnetic beads were suitable to detect the presence of NP-specific antibodies. The assay needs only a magnetic rack and a pipettor to be performed. The results were available within 30 min. The positive results were observed as yellow color visually but also read in ELISA reader as OD values. The sensitivity of this assay was 1:108 dilutions. The cross-reaction panel was negative with different pathogens and negative human plasma. Conclusions. This work may be the first report in literature about the development of a magnetic beads ELISA as a point of the care assay, which is reproducible, highly sensitive, robust, and easy to perform. It was used to detect the presence of NP-specific IgG antibodies in the plasma samples successfully. This assay can be used as a professional assay, where the results can be measured with an ELISA reader. This assay may be suitable in small clinics also under field conditions. It can be used to detect the SARS CoV-2 infection in vaccinated persons (S protein-based vaccines) along with non-vaccinated population in latent and active phase.
Adaptation Processes Among Internally Displaced Persons in Ukraine During the Russia-Ukraine War in the ХХІst Century
Authors: Borysenko Valentyna
Published: December 2023

This research exploration issues related to the living conditions and psychological well-being of internally displaced persons (IDPs) during the russo-Ukrainian war in Ukraine, using a case study of one territorial community in Vinnytsia Region. The geography of the newcomers to Yampil Microregion encompasses various cities and villages in the East and South of Ukraine. The majority of IDPs came from Kyiv, Odesa, Kharkiv, Mykolaiv, Donetsk, and Kherson. The picking of the region for relocation was primarily influenced by existing acquaintances and offers from relatives and classmates. Some IDPs, however, ventured into the unknown, relying on advice from volunteers. This group of individuals is particularly vulnerable due to their sense of helplessness and psychological state in a new environment, especially for those IDPs who were placed in rural areas. Not all IDPs immediately started to put their household in order. Nonetheless, some started to renovate vacant houses and the surrounding areas, and they gratefully accepted assistance from the local population, which provided various household items, clothing, and food. Families that decided to stay and purchased housing integrated most actively into the new conditions. The living conditions of IDPs, interpersonal relationships between local and newcomer populations, and the selflessness and hospitality of the local residents towards those affected by the conflict are also discussed. Nostalgic sentiments among IDPs for their homeland are noted, even though their homes have been destroyed by the aggressors. Based on conducted interviews, it can be concluded that different social groups of IDPs experience adaptation to new geographical conditions differently. Emphasis is placed on the common factors influencing the settlement of IDPs in Yampil Microregion and the display of individual characteristics among IDPs. It has been found that a significant number of IDPs do not rely solely on state aid and the welcoming community but have started their own businesses, making the adaptation process less painful. It is noted that different age groups perceive their temporary stay differently but nearly all of them hope to return to their homes. The issue of insufficient attention to integration processes during the pre-war period is raised, emphasizing the need to strengthen patriotic education in society.
Baroque Iconostases of Eastern Podillya: the Main Structural Types
Authors: Khodak Iryna
Published: December 2023

The iconostases of Eastern Podillya remain a little-known phenomenon that has been ignored by researchers of sacred art, with the exception of Oleh Sydor. The purpose of the article is to analyze and systematize the Eastern Podillya Baroque iconostases (based on the material of Vinnytsia region) by the types of constructions. The analysis of the preserved sacral ensembles and photographs of the lost ones gave reasons to identify four main groups of architectural structures. The monuments of the first group had a strictly horizontal layout of tiers, and the central vertical division was accentuated by larger elements and richer wooden carvings. In the second group, a gradual scale increase toward the centre is observed, starting, as a rule, from the Festival tier. For this purpose several methods were used: cornice bending above the deacon’s doors; placing above the nave row (between the deacon’s doors) an additional tier, mostly of Pentecost Sunday, or a decorative carved or painted panel, etc. Characteristic of the next type is the arched arrangement of the icons of the upper tiers of the middle part, starting from the Festival row. Finally, the fourth group comprises iconostases with creases symmetrical to the central axis, with the tiers in such ensembles being arranged on the same level or in stepwise order. The iconostases of the first three types had a straight line in the plan (alternatively, the side wings were wrapped around the log cabin walls), while the monuments of the fourth type had a broken (zigzag) line. Considering the limited amount of visual material involved, further research prospects depend on the discovery of new sources (iconostases, photographs or sketches), the study of which will allow verifying the conclusions made.
Índice por temas 2023
Authors: (RAAOT) Equipo Editorial
Published: December 2023

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novas tecnologias como instrumentos semióticos e culturais de aprendizagem
Authors: Dos Santos Sousa Miranda Gilmar , Catosso Salles Atílio , Pereira de Faria Joelma  , Pioli Márcio
Published: December 2023

Pesquisas atuais sobre o avanço das novas tecnologias vêm despertando largas reflexões e contendas sobre novos desenhos e/ou modalidades educacionais, bem como discussões sobre as transformações do papel do educador. Paralelamente, afloram questões sobre a aprendizagem mediada pelas tecnologias educacionais. Buscando elucidar tais questões, este estudo procurou compreender como os princípios da teoria histórico-cultural podem coadjuvar na prática docente frente à eclosão de novas ferramentas e instrumentos digitais no contexto educacional. Contempla-se, assim, um possível diálogo com os pressupostos da perspectiva histórico-cultural, incorporando os conceitos de instrumentos, mediação, aprendizagem e desenvolvimento, da teoria de Vigotsky, com as tecnologias digitais presentes no cotidiano educacional, se orientando, então, por esse viés teórico e metodológico, e com base em uma pesquisa bibliográfica de artigos que também buscam essa correlação. Destarte, esta pesquisa bibliográfica, de natureza qualitativa, almejou buscar e analisar artigos que fazem essa articulação teórica entre os principais conceitos da perspectiva histórico-cultural com as novas tecnologias. Conclui-se que a teoria histórico-cultural pode contribuir nos estudos sobre o processo de mediação e de utilização dos instrumentos tecnológicos na educação, bem como uma possibilidade de aplicação dos pressupostos vigotskyanos para nortear a prática do professor no que se refere ao processo de instrumentalização, mediação, ensino e aprendizagem.
ensino do processo criativo do ato projetivo em arquitetura
Authors: Labronici Baiardi Yara Cristina
Published: December 2023

O objetivo deste artigo é investigar caminhos metodológicos no processo de ensino-aprendizagem de modo a motivar o estudante na construção contínua de um sistema autônomo do pensar-fazer-refletir do ato projetivo no campo da Arquitetura e do Urbanismo.
Desafios e perspectivas da gestão escolar democrática com a implementação da BNCC
Authors: Farias Viana Andrezza , Alves Schmitt Lilian
Published: December 2023

A pesquisa, que consiste em uma análise documental e bibliográfica, teve como objetivo compreender o papel da gestão escolar na implementação da Base Nacional Comum Curricular (BNCC) (BRASIL, 2017) a partir da análise do documento Guia de implementação da base. Os objetivos específicos são: descrever os aspectos históricos da construção da BNCC; apontar as controvérsias em torno da proposição e da implementação da BNCC; identificar as perspectivas de gestão escolar indicadas pelo documento Guia de implementação da base. Assim, por meio de uma revisão bibliográfica, abordou-se uma problematização sobre as relações entre gestão escolar democrática e implementação da BNCC, tema relevante para o sistema de ensino. A escola é lugar de constante realização e avaliação de sua proposta educativa, uma vez que necessita organizar seu trabalho pedagógico com base em seus estudantes. Nesse sentido, é fundamental que – ao mesmo tempo em que assuma suas responsabilidades com relativa autonomia, sem esperar que as esferas administrativas superiores tomem essa iniciativa – a comunidade escolar lute pelas condições necessárias para levar sua proposta adiante, uma proposta de currículo para fins emancipatórios e descentralizados. Concluímos que a BNCC vem para normatizar o currículo escolar, mas é preciso ter cuidado para que ele não se torne engessado. Também concluímos que o Guia para gestores escolares apresenta uma proposta de prática democrática; no entanto, apenas o guia não garante essa prática.
Cultura escolar indígena e BNCC
Authors: Bitencourt Frigheto Sirlete Maria , Marques Costa Joacir , Avila de Lima Carlos Edimilson
Published: December 2023

Na contemporaneidade, a discussão em torno da educação escolar indígena torna-se um desafio e uma luta que não podem ser negligenciados. Com isso, este texto parte da problemática: quais discursos são produzidos na Base Nacional Comum Curricular (BNCC) acerca da educação escolar indígena, considerando a prerrogativa do direito à educação e o reconhecimento dessa cultura? Objetiva-se, assim, compreender as relações entre a educação escolar indígena e a BNCC na perspectiva do direito à educação e do reconhecimento da cultura. Para tanto, a materialidade discursiva foi produzida com base na política educacional e nas experiências em contexto escolar indígena, tendo na análise do campo discursivo a base epistemetodológica. A educação formal nesse contexto é uma conquista, de modo que a produção curricular pode reconhecer diferenças culturais e linguísticas de um povo.
Palavras-chave: BNCC; Educação escolar indígena; Política educacional.
Prevention of Technology Addiction: Domestic Experience and Foreign Initiatives
Authors: Popov Pavel M. , Rezer Tatiana M.
Published: December 2023

Introduction. The article presents the findings after the analysis of domestic and foreign practice in the field of prevention of cyberaddictive patterns of behavior. The purpose of the study: by means of comparative analysis of domestic and foreign studies of technological addiction, to develop a classification of preventive measures against technological addiction in modern humans and to determine the main forms of technological addiction and its characteristics.
Materials and Methods. The research methodology is based on the theory of biosocial human development using systemic and socio-digital approaches to the study of the problem of technological addiction. With the help of comparative and theoretical methods of analysis, a classification of the prevention of technological addiction in humans has been developed and the main characteristics of the forms of technological addiction have been determined. Legal acts for determining the directions of state policy in Russia as preventive measures are studied.
Results. The concept of “technological addiction” has been clarified. The classification of forms of technological addiction of modern man is carried out. The main characteristics of each form of technological addiction are determined. The approaches applied to the prevention of technological addiction in the foreign practice are highlighted: inaction, encouragement and dissemination of research in the field of prevention of forms of technological addiction, education, support for families and public organizations. In Russia, the directions of state policy in the field of prevention of technological addictions represent the purposeful activity of public authorities and a system of measures of a regulatory, economic, informational, educational, organizational, managerial and other preventive nature.
Discussion and Conclusion. The obtained results contribute to the research base for the prevention of technological addiction, determine the definition of promising preventive approaches. The results of the analysis show cultural differences in the level of spread of technological forms of addiction, which requires further study.
Die Aucissafibeln in der römischen Provinz Pannonia
Authors: Berecz Katalin
Published: December 2023

The paper is dealing with 194 Aucissa brooches from 27 sites in the Roman province of Pannonia, based on the results and methodology of international archaeological and historical research. Aucissa fibulae, as costume items, are one of the leading artefacts of the early imperial period, initially used mainly by soldiers (sagum), and are therefore an important archaeological source for the Roman expansion, occupation and Romanisation. In Pannonia 98% of the Aucissa fibulae were recovered from settlements, mainly from the early layers of military forts and later towns. The material of the fibulae is bronze, there is only a single known item being silver-plated. The formal, technological and chronological analysis of the Aucissa fibulae in Pannonia is followed by a costume, historical and archaeological analysis. The Aucissa brooches in Pannonia can be dated from the beginning of the 1st century A.D. to the first decades of the 2nd century A.D. The earliest types (subtypes A242.1,2,3) are found in military forts along the Roman expansion trail. The Aucissa brooches come from the areas of the East–West military expansion route (the Drava-Save interfluve, Siscia, Sirmium, Gomolava), the North–South expansion route to the Danube (Amber Road, Salla, Savaria, Carnuntum) and the Danube limes (Brigetio, Matrica, Rittium). The smaller number of later types of fibulae (subtypes A242.4,5,6) found in the interior of the province of Pannonia (vici) indicates a process of Romanisation of the local population (Bátaszék, Csákberény, Mezőörs). The Aucissa brooches can also refer to cultural and trade relations with the Barbaricum (Púchov culture); they can indicate the movement of the Roman army (Devín, Mušov) and also the mobility of people (Veresegyház, Szeged). In some places Aucissa brooches later appeared in the clothing of civilians and women (Emona).
Das Gräberfeld des römischen vicus bei Biatorbágy
Authors: Ottományi Katalin
Published: December 2023

Near Biatorbágy, along the northern side of Road 100, Éva Maróti, archaeologist of the Ferenczy Museum of Szentendre, excavated a part of a cemetery in 2004. 36 early and late Roman graves were found with Avar Period burials mixed in between. The cemetery was used from the second half of the first century to the end of the fourth one. An early Roman horse burial and several undamaged bronze vessels are among the most significant finds. The cemetery begins with three indigenous skeletal burials followed by four cremation ones from the 2nd and 3rd centuries and 27 skeletal burials appearing in the second half of the 3rd century. The richer part of the 4th-century population was buried in stone or brick walled graves. Most grave goods were in the stone walled graves. Glazed jugs and female jewellery must be highlighted amongst these grave goods. The cemetery most likely belonged to the Roman settlement excavated on the border of Biatorbágy and Törökbálint being inhabited for several centuries. The burials fit in with the cemeteries of the vici (Budaörs, Biatorbágy, Páty) in the southwestern area of Aquincum.
Update on long-term prophylaxis in hereditary angioedema with decreased C1 inhibitor
Authors: Rodríguez Bote M.D. , Fernández Delgado L. , Conde Alcañiz A. , Guardia Martínez P.
Published: December 2023

This paper brings up two patients with hereditary angioedema and decreased C1 inhibitor, who after several years on treatment with attenuated androgens as long-term prophylaxis (LTP), have developed side effects that entail a necessary change in their treatment. First, the available treatment options and their possible side effects are reviewed. Second, the new therapeutic indications for the management of hereditary angioedema with decreased C1 inhibitor are described, according to the new management guidelines. In this guideline, plasma concentrates of C1 esterase and the monoclonal antibody Lanadelumab are proposed as the first-line treatment for LTP, while attenuated androgens are relegated as a second-line choice due to the risk of possible side effects.
Towards enhancing ODS composites in laser powder bed fusion: Investigating the incorporation of laser-generated zirconia nanoparticles in a model iron–chromium alloy
Authors: Goßling Mareen , Rittinghaus Silja-Katharina , Bharech Somnath , Yang Yangyiwei , Wilms Markus B. , Becker Louis , Weber Sebastian , Xu Bai-Xiang , Gökce Bilal
Published: December 2023

Oxide dispersion-strengthened (ODS) steel is a sought-after composite material known for its high demand in high-temperature and corrosive environments. Achieving the desired ODS steel properties requires specific conditions for the size and nanoparticles (NP) distribution in the printed part. Laser ablation in liquid (LAL) enables precise NP size adjustment. At the same time, the dynamic melt pool solidification in the Laser Powder Bed Fusion (PBF-LB/M) process complements this by creating favorable conditions for successful ODS processing. In this study, ZrO2 NP with a small and narrow particle size distribution (d50 = 3.8 nm; d90 = 10 nm) is produced by LAL. Dielectrophoretic deposition achieves the homogeneous, deformation-free coating of the binary Fe20Cr (wt.-%) matrix powder with NP. PBF-LB/M printed parts out of the oxide-additivated powder exhibit a crack-free structure and a density of up to 98%. Expectedly, the metal matrix grain sizes and room temperature microhardness (~ 220 HV) are not affected by NP addition. NP tracing by 2D simulation indicates a homogeneous NP distribution and less than 10% NP to be agglomerated in the solidified part. Thus, a promising perspective for a complete laser-based process chain for generating and processing ODS alloys is outlined.

Graphical abstract
Structure optimization of large-solid-core photonic crystal fibers based on Ge\(_{20}\)Sb\(_{5}\)Se\(_{75}\) for optical applications
Authors: Ngoc Vo Thi Minh  , Danh Nguyen Thanh  , An Nguyen Manh  , Tham Tran Hong  , Van Thuy Hoang  , Lanh Chu Van  , Le Van Hieu
Published: December 2023

This paper presents a new design of Ge20Sb5Se75 large-solid-core photonic crystal fiber (PCF) with a 1st-ring-removed square lattice. Using the full vector finite element method for anisotropic perfectly matched layers, we numerically examine the dispersion characteristics of the PCF in the wavelength range spanning from 1.5 µm to 6.0 µm. The results reveal that photonic crystal fibers exhibit a variety of dispersion properties, including all-normal and anomalous dispersion, featuring one or two zero dispersion wavelengths (ZDWs). We propose two designs with optimal dispersion characteristics based on our numerical simulations. These designs have small lattice constants (Ʌ = 1.0 µm; Ʌ = 1.5 µm) and low fill factors (d/Ʌ = 0.3; d/Ʌ = 0.35). Furthermore, these selected fibers offer high nonlinearity and low confinement loss, making them excellent candidates for a wide range of optical applications.
Chaotic dynamics of a double-well Bose-Einstein condensate.
Authors: Rajagopal Kalai Kumar , Cheng LongJun
Published: December 2023

We study the dynamics of a double-well BEC system subjected to oscillating dissipation. The macroscopic model is described within the mean-field approximation while noise effect due large reservoir fluctuation has been averaged out to zero. We chose a simple dissipative memory kernel to produce a time-dependant oscillating dissipation. Our numerically calculated phase-space and Lyapunov exponents shows enhances route to chaos as one increases driven dissipations amplitude.
"Don't sow, grow offshoots!"
Authors: Calås David
Published: December 2023

This paper considers the intersection of arts, culture, and entrepreneurship (ACE) through a novel lens, drawing on Deleuze and Guattari’s dichotomy of arboreal and rhizomatic knowledge structures. First, existing literature reviews on cultural entrepreneurship and arts entrepreneurship are critically explored. This exploration highlights the predominance of arboreal (tree-like, hierarchical, and genealogical) thinking in current ACE research as well as in conventional practices of doing and presenting literature reviews. As a challenge to this norm, a rhizomatically inspired research agenda for the intersection of ACE is proposed. By discussing the challenges of doing research in a transdisciplinary and intersectional research context, the paper ultimately considers how scholars and practitioners can understand this complexity by embracing Deleuze and Guattari’s rhizomatic principles in future research.
L’histoire de l’intégration européenne
Authors: Koźbiał Krzysztof
Published: December 2023

L’intégration des États, tant sur le plan politique qu’économique, est certainement un des processus qui ont caractérisé le continent européen après la Seconde Guerre mondiale. Certes, des tentatives et des propositions d’intégration avaient déjà été faites auparavant, mais ce n’est qu’après 1945 qu’elles ont été effectivement mises en œuvre. La création de la Communauté européenne du Charbon et de l’Acier en 1951, puis de la Communauté économique européenne et de l’Euratom en 1957, a induit une coopération étroite entre les pays de la partie occidentale de l’Europe, mais ce n’est qu’après la chute des régimes communistes que la voie a été ouverte à l’intégration de l’Europe centrale et orientale (en 2004 et en 2007). À l’heure actuelle, l’Union européenne, qui compte 27 pays, est sans aucun doute l’exemple d’intégration qui a le mieux réussi dans le monde. Cette organisation a évolué à la fois en termes de nombre d’États qui y adhéraient et d’étendue de la coopération entre ceux-ci. Comme toute autre forme de coopération, elle a connu des crises, mais a su les surmonter. Un nouvel élargissement de l’UE aux pays des Balkans est possible dans un avenir proche.
L’expérience de Karol Wojtyła dans le dialogue international et l’intégration européenne. Idées et pratiques choisies de l’époque cracovienne (1938–1978)
Authors: Białkowski Michał
Published: December 2023

L’expérience de l’européanisme, du dialogue international, de l’accord et de l’intégration européenne constituent une part essentielle de la biographie de Karol Wojtyła dans sa période cracovienne (années 1938–1978). Parmi les nombreux évènements qui ont influencé sa perception de l’Europe comme centre culturel et civilisationnel, il convient d’abord de mentionner ses études de philologie polonaise à l’Université Jagellonne. Ce sont ces études qui lui ont donné des bases solides en littérature et en art dramatique. Les années de la Seconde guerre mondiale : l’occupation, l’anéantissement de la population juive et son sort après la guerre ont également renforcé la valeur de l’unité européenne. Par contre, son voyage dans la Ville éternelle, la préparation de son doctorat et la possibilité de visiter les pays de l’Europe de l’Ouest ont renforcé l’importance du christianisme en tant qu’élément durable de consolidation de l’Europe. Son expérience du concile Vatican II qui lui permit de rencontrer les représentants de nations, de cultures et de races du monde entier fut exceptionnelle. Ce fut également un moment clé dans l’histoire du dialogue germano-polonais, dont le point culminant fut la visite en République fédérale allemande en 1978.
Społeczne konteksty rodziny. Prawo - polityka społeczna - wychowanie
Authors: Kluz Marek , Olejnik Bogumiła , Młyński Józef
Published: December 2023

The monography entitled „Social contexts of the family” deals with topics in three aspects: law, social policy and education. The starting point is the right to contract a concordat marriage by a faithful of Catholic church in Poland, the possibility of a canonical marriage without civil effects. In the main part of the issue of moral principles in political activity, in the field of upbringing and shaping the personality of a child in the family and at school, and the impact of contemporary earning functions on the marital and family bond with the consequences of separation in marriage and family. The second part focuses on the social effects and social determinants of life of people at the end of their lives, care and communication in social services, work as an area of social support for a dysfunctional family, family security in the social policy environment and work as part of social assistance management. In the last part of the monography, the subject of the social dimension of life in the upbringing environment was discussed. The functions of work and education, as an expression of care for man, are also outlined. In addition, education to basic social and moral values in the family, which are a challenge for modern civilization, was indicated.
W świecie zagubionego słowa. Nieprawda, postprawda, hejt
Authors: Zwoliński Andrzej
Published: December 2023

The search for truth has always been a constant human effort. However, on his path man has to face many obstacles. He is often tempted to tell lies or falls into the trap of post-truths and manipulation, and then he tends to replace kindness and respect with hate speech, which he expresses with either words or graphics. Finally if everything else fails, he resorts to judgment, which invariably leads to depreciation of human dignity.
Oddziaływanie pochwał wyrażanych przez rodziców na relacje pomiędzy rodzeństwem
Authors: Gadamska-Kyrcz Magdalena
Published: December 2023

The word „praise” is usually associated with something pleasant and positive. There is nothing strange about it, because praise can motivate to act and be nice to the person who receives it. It seems, therefore, that praising children by parents does not involve any kind of threat. But is it really so? The article deals with the issues related to upbringing, and more specifically the impact of praise from parents on relationships between children. Among other things, the issue of what praise is and what consequences it can have for the relationship between brothers and sisters was raised here. The way parents relate to their children, what messages they use, among others, when praising, seems to be important in the formation of the parent-child relationship, but also the relationship between siblings.
Nienawiść w języku polityki. Agresja werbalna w wypowiedziach posłów na Sejm Rzeczypospolitej Polskiej w roku 2023
Authors: Grunwald Jadwiga
Published: December 2023

This article examines verbal aggression in the lower house of Polish Parliament (Sejm) in of the 9th term. Based on shorthand notes of Sejm’s sessions no. 70, 71 and 72 that took place in January and February 2023, a list of the most common manners of depreciating political opponents and their actions has been compiled. The research material under analysis shows that Sejm members often use various types of violations of the principles of language ethics and verbal etiquette, for example the opposition “We” and “They” and other generalizations, labelling, a strategy of verse and jokes, strategic use of metaphorical semantic explanations, as well as a wealth of metaphors and comparisons.
Destrukcja języka w komunikacji internetowej adolescentów
Authors: Buksa Łukasz
Published: December 2023

About young people’s communication through the Internet a lot has already been said, but this knowledge still needs to be updated due to the emergence of new phenomena. Some of them include the destruction of language in online communication, which translates into social life and has its destructive, disastrous reminiscences in interpersonal relationships. A significant drawback of Internet communication is mediated nature, muting of many communication channels, and the lack of indicators of the recipient’s emotions on the sender’s verbal message. This leads – for example – to building barriers due to misunderstanding, lack of dialogue culture, devaluation of words through the expansion of acronyms, fake news, post-truth, consent to vulgarisms, verbal violence through hate. Young people easily move from verbal violence and contempt for other people to psychological violence in the form of cyberbullying, as well as physical violence, sometimes leading their peers to death.
Escritura, creatividad e historia de Cartagena
Authors: Cera-Ochoa Raúl Antonio
Published: December 2023

En septiembre de 1922, nace en Cartagena Judith Porto de González o cómo será apodada más adelante, la niña Juyi; mujer que ocupará un lugar señalado en la literatura nacional e internacional y será figura entre las principales escritoras del país, “conocidas y reconocidas como una de las mejores plumas americanas” (Vargas, 1991). La palabra escrita por Judith Porto coincide con una irrupción significativa de las mujeres colombianas casi violentamente en los espacios reservados para la opinión masculina.
Nomofobia y el nivel productividad de las organizaciones
Authors: Morales Ospina Alberto
Published: December 2023

La nomofobia, es un término acuñado después de la investigación realizada en el 2011 por la empresa británica SecurEnvoy, la necesidad de entender la relación de sus trabajadores con su teléfono móvil y el impacto de esta con la productividad de la empresa, llevaron a la realización de mencionado estudio, más claramente, la productividad había bajado a niveles preocupantes, los resultados se han generalizado a nivel global, los teléfonos móviles cambiaron la manera de relacionarse las personas de todo el mundo y las empresas se ven afectadas con este cambio en la conducta social, el objetivo de esta investigación es el encontrar la afectación que tiene la nomofobia en la productividad de la Universidad San mateo, para ello se aborda una metodología mixta de investigación, en busca de poder utilizar todas las herramienta posibles de recolección de la información que aportan los métodos cualitativos y cuantitativos, en conclusión la investigación validará la hipótesis que se refiere al impacto innegable que tiene la nomofobia en la productividad de la universidad.
Palabras de Presentación, curiosidades y agradecimientos
Authors: Norman-Acevedo Eduardo
Published: December 2023

Iniciación Científica colabora de forma permanente con instituciones de educación superior - IES, organismos públicos y privados; y, agentes sociales, en la formación, desarrollo y divulgación de la investigación para lograr una asertiva incidencia en la sociedad. Dentro de las actividades permanentes como red (transe- inter) institucional, es la organización de escenarios para la presentación de resultados científicos en las diversas áreas del conocimiento. En este propósito se inscribe la colaboración con veintiocho (28) IES Colombianas en la estrategia de apropiación social del conocimiento bautizada: XPOILERS: Festival de Stand up científicos e investigativos.
Cartografía social para la educación ambiental en las comunidades vulnerables con capacidades diferentes de Ciudad Bolívar parte alta
Authors: Salamanca Ladino Nahir Saraí , Guzmán Roa Elkin Andrés , Aguilar Vega Ramón Gabriel
Published: December 2023

En este capítulo se muestra la creación de cartografía social con los estudiantes y la Fundación Colombia Empoderada durante el periodo 2019-2020; especialmente enfocado a las metas de los Objetivos de Desarrollo Sostenible – ODS; como estrategias de educación ambiental, preservación, conservación de los ecosistemas terrestres, acciones por el clima, entre otros. Los componentes realizados en el proyecto son: consolidar un sistema de información sobre los ecosistemas estratégicos lenticos y loticos para que se puedan tomar medidas preventivas que reduzcan la vulnerabilidad y la generación del riesgo, en segundo lugar, lograr la igualdad entre la población discapacitada en el acceso de educación ambiental. La estructura social y ambiental de la localidad Ciudad Bolívar se evidencia un abandono de las comunidades vulnerables, la falta de acceso a una educación de calidad de las personas en condición de discapacidad y desprotección. La importancia de la georreferenciación y cartografía social para poder tomar decisiones, y lograr disminuir la inclusión social en la zona para continuar con las especificaciones sociales de la Agenda de sostenibilidad ambiental frente a los ecosistemas estratégicos en defensa del territorio como Cerro seco, Quebrada limas y Humedal terreros. Los cuales están casi extintos no se conocen y siempre han sido parte de las circunstancias sociales y ambientales de la población.
La importancia de la educación en estadística y las limitaciones en su formación a partir de los significados de los profesores en formación
Authors: Vargas-Delgado Leonardo José , Ávila-Toscano José Hernando , Escorcia-Pérez Keiner , Molina Camilo
Published: December 2023

INTRODUCCIÓN: La estadística no goza de buena reputación en la educación escolar, incluso educadores matemáticos en formación y en ejercicio muestran debilidades en esta disciplina. OBJETIVO: Este estudio buscó identificar los significados de maestros de matemáticas en formación inicial en relación con la importancia de la educación estadística y caracterizar su perspectiva sobre limitaciones en su proceso formativo en el área. MATERIALES Y MÉTODOS: Este estudio cualitativo evaluó diez participantes mediante un cuestionario enfocado en la importancia de la estadística y las limitaciones percibidas sobre su formación en esta área en su carrera profesional. RESULTADOS Y DISCUSIÓN: Empleando análisis de contenido temático se identificaron significaciones que resaltan la utilidad de la estadística para resolver problemas, emergieron también insatisfacciones frente a la enseñanza de la disciplina. CONCLUSIONES: Concluimos que, si bien futuros maestros perciben la estadística como relevante, asumen la formación recibida como tradicional, desprovista de contexto y sin empleo de la investigación como estrategia aplicada del razonamiento estadístico.
EL PROCESO DE INVESTIGACIÓN Y SU RELACIÓN CON LA MOTIVACIÓN INTRÍNSECA Y EXTRÍNSECA
Authors: Obando-Montoya Jorge Didier
Published: December 2023

El proceso de investigación CAS (Creatividad, actividad, servicio) del IB (Bachillerato Internacional) es el resultado de un proceso reflexión en torno a la práctica de enseñanza aprendizaje en el aula de clase y el trabajo realizado a través de los proyectos de investigación que hace parte del CAS. Este proceso tuvo lugar en la Institución Educativa (I.E) Juan María Céspedes ubicado en la Ciudad de Medellín de Colombia, en el Barrio Belén de la Comuna 16. A partir de dicho proceso se establecieron proyectos de investigación que buscaron describir si por medio de ellos y de las competencias investigativas que involucran, se incrementaría la motivación intrínseca y extrínseca de los estudiantes. La investigación se desarrolló mediante el estudio de caso desde un enfoque cualitativo a cuatro estudiantes de grado décimo seleccionados a conveniencia con los cuales se aplicaron técnicas como grupo focal, cuestionario y observación no participante. Como resultado de esta investigación se encontró que es pertinente promover en la escuela escenarios de investigación donde los estudiantes desde un tema particular que tenga significado para su vida se les invite a indagar al tiempo que les posibilita una mayor motivación intrínseca, extrínseca y disposición para aprender.
Language Practices of the Brothers Simolin, Russian Foreign-Born Diplomats, in the Second Half of the 18th Century
Authors: Petrova Maria
Published: December 2023

This article considers the usage of native and foreign languages in the multinational community of Russian diplomats in the second half of the eighteenth century, especially by the immigrants from the Ostsee (Baltic) provinces of the Russian Empire annexed as a result of the Great Northern War of 1700–1721. Incorporating the approaches of new diplomatic history that applies the methods of sociolinguistics and studies, among others, the national, social and cultural identities of international actors, the author examines language practices and language competences of Swedes Karl Gustav (Karl Matveevich) and Johann Matthias (Ivan Matveevich) Simolin in the context of their career strategies. The study refers to their correspondence with Russian monarchs and the leadership of the Collegium of Foreign Affairs over the 1740s–1780s kept in the Archive of Foreign Policy of the Russian Empire and the Russian State Archive of Ancient Documents. The reconstruction of both brothers’ career paths reveals that they used similar language competences they initially had in different ways. Karl Gustav, the elder brother, translator, and polyglot, was responsible for correspondence in German in the Collegium of Foreign Affairs for many years. However, when he received an appointment to Mitau, his only diplomatic post, in 1758, he began to conduct official correspondence in the Russian language. Johann Matthias, the younger brother, spent most of his life abroad and, starting from 1758, held diplomatic posts in Regensburg, Copenhagen, Stockholm, London, and Paris. German that he spoke as a native speaker and French were his main languages of correspondence with the Russian monarchs and the leadership of the Collegium of Foreign Affairs. French gradually replaced German in documents of all types as the language of international and court communication. In addition, Simolin understood the Russian language perfectly, which, from the mid‑1770s, spared the Collegium from having to translate rescripts sent to him on behalf of the empress. The analysis of both brothers’ language practices demonstrates that despite the introduction of French into the internal correspondence of the Collegium of Foreign Affairs in the second half of the eighteenth century, the new subjects of the Russian Empire found it necessary to learn Russian to gain promotion and become part of the Russian imperial elite.
The Concepts of Power and State in Russian Political Thinking: On the Difficulties of the Comparative Approach
Authors: Vysokova Veronika , Kiselev Mikhail
Published: December 2023

This article reviews a monograph by E. Sashalmi, a Hungarian Russianist, dedicated to the “transtemporal” reconstruction of the political thinking of Russian writers of the early modern period. The innovation of this book lies in the “contextual” and historical-comparative approaches. Comparing the political discourse of Muscovy with the Western Christian political thought of the sixteenth and seventeenth centuries, the author does not find the concepts of “sovereignty”, “state”, or “politics” in Russian political thinking. E. Shashalmi connects the adaptation of the idea of a “modern sovereign state” in Russian intellectual discourse with Western Russian intellectuals of the second half of the seventeenth century and Feofan Prokopovich in the early eighteenth century. While appreciating the innovative character of the research goal and approaches, the reviewers evaluate the Hungarian historian’s conclusions as historiographic clichés about the immaturity of Russian culture and the political thought of pre-Petrine Rus’. In fact, E. Shashalmi’s research concerns the Westernisation of Russian political thought. The reviewers conclude that the main difficulty of such innovative historical and comparative studies is the problem of translatability of “concepts” from one culture to another.
Laboratory markers of osteosarcopenic obesity
Authors: Gritsenko O. V. , Gruzdeva O. V. , Chumakova G. A. , Barbarash O. L.
Published: December 2023

Osteosarcopenic obesity syndrome involves the simultaneous deterioration of bone, muscle, and excess fat accumulation, resulting in systemic metabolic dysregulation. Currently, the relevance of this problem is increasing due to the global population aging, the high incidence of obesity, type 2 diabetes, sarcopenia and frailty in developed countries of the modern world. In this regard, novel diagnosis methods for this condition, including laboratory markers, should be developed. The review examines modern biomarkers of osteosarcopenic obesity.
Study of Therapeutic Mechanisms of Bupi Yichang Formula against Colon Cancer Based on Network Pharmacology, Machine Learning, and Experimental Verification
Authors: Du Juan
Published: December 2023

Bupi Yichang formula (BPYCF) has shown the anti-cancer potential; however, its effects on colon cancer and the mechanisms remain unknown. This study intended to explore the effects of BPYC on colon cancer and its underlying mechanisms. BPYCF-related and colon cancer-related targets were acquired from public databases, followed by differentially expressed genes (DEG) identification. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed using clusterProfiler. A protein-protein interaction (PPI) network was constructed using STRING database. CytoHubba and MCODE to screen the hub targets. A diagnostic model was built using random forest algorithm. Molecular docking was conducted using PyMOL and AutoDock. High-performance liquid chromatograph-mass spectrometry (HPLC-MS) analysis and in vitro validation were performed. Forty-six overlapping targets of BPYCF-related, colon cancer-related targets, and DEGs were obtained. GO and KEGG analyses showed that the targets were mainly enriched in response to lipopolysaccharide, neuronal cell body, protein serine/threonine/tyrosine, as well as C-type lectin receptor, NOD-like receptor, and TNF signaling pathways. Five targets were identified as the pivotal targets, among which, NOS3, CASP8, RIPK3, and TNFRSF10B were stably docked with the core active component, naringenin. Naringenin was also identified from the BPYCF sample through HPLC-MS analysis. In vitro experiments showed that BPYCF inhibited cell viability, reduced NOS3 expression, and elevated CASP8, RIPK3, and TNFRSF10B expression in colon cancer cells. BPYCF might treat colon cancer mainly by regulating NOS3, CASP8, RIPK3, and TN-FRSF10B. This study first revealed the therapeutic effects and mechanisms of BPYCF against colon cancer, paving the path for the development of targeted therapeutic strategies for this cancer in the clinic.
ON DRAIN OF RADIATION DEFECTS FROM WORKING AREA OF AN INTEGRATED CIRCUIT
Authors: Pankratov Evgeny L.
Published: December 2023

In this paper we introduce an approach to organize a drain of radiation defects. These defects were generated during ion doping and other types of radiation processing of the working area of integrated circuits manufactured in the framework of a multilayer structure. The approach is based on the difference between the properties of materials of the layers in the considered multilayer structure. An analytical approach for analysis of mass and heat transfer in multilayer structures was introduced with an account of the spatial and temporal variations of their parameters, as well as the nonlinearity
of the considerate processes.
Региональные программы материнского капитала: влияние на рождаемость в России
Authors:   HSE University, Vakulenko E. S. , Ivashina N. V. ,   Far Eastern Federal University, Svistyilnik Y. O. ,   Far Eastern Federal University
Published: December 2023

Despite an active demographic policy, the birth rate in Russia has been declining since 2015. Since 2007, federal maternity capital (FMC) programme has been implemented. In 2011, some Russian regions additionally introduced regional maternity capital (RMC). The paper aims to assess the impact of RMC on fertility in Russian regions. To this end, econometric models using panel data from the Federal State Statistics Service for 1996-2020 were utilised. A positive impact of regional maternity capital for a second child on fertility was revealed. The study demonstrated that this support measure is most effective in predominantly Orthodox regions, as well as in regions with a higher total fertility rate (more than 1.7). According to the analysis, it is necessary to raise RMC payments for a second child to the level of federal maternity capital, all other things being equal, in order to increase the average total fertility rate to 1.7. Fertility is negatively correlated with the average per capita income, housing costs, unemployment rate and preschool enrolment, as well as positively correlated with federal maternity capital and marriage rate. As a result, the state has to continue and improve maternity capital programmes for the purchase of housing for families with children, support them in the labour market, improve preschool infrastructure, and also to pursue a pro-natalist policy aimed at strengthening the family institution and preserving family values. Due to the specificity of data, an influence of regional maternity capital on changes in birth timing and purposes of the capital’s possible spending were not considered. Further research should focus on determining priority forms of providing regional maternity capital according to the intended use.