bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN KOMUNIKASI ANTARA MAHASISWA DAN DOSEN PEMBIMBING SKRIPSI DENGAN STRES DALAM MENYUSUN SKRIPSI PADA MAHASISWA S 1 KEPERAWATAN STIKES RANAH MINANG TAHUN 2015
Authors: Julianti Rina , Yulia Aida
Published: February 2022

Abstract Thesis is one of the obligations that must be completed an undergraduate students (S1) as a condition that must be worked out before obtaining a degree. Problems while working on the thesis, the main difficulty is the thesis supervisor elusive, in the guidance of professors just cross out the mistake and did not explain to the students about the error. So that students feel anxious, appetite is reduced, complained of frequent headaches, anxiety and sleeplessness as much thought thesis. The purpose of this study was to determine the relationship of communication between the student and the thesis supervisor with stress in a student writing his thesis on S 1 Nursing STIKes Minang 2015.This type of research is analytic with cross sectional study design. The population in this study were all students of grade IV Prodi S-1 Nursing STIKes Minang Padang totaling 80 samples. The sampling technique in total population. Data were collected using a questionnaire on 4 to 14 September 2015. The univariate analysis is shown in the form of a frequency distribution table and bivariate analysis shown by the results of the chi square test.. The result showed 80 people as much as 45% of communication between students is not good. As many as 65% of students experienced stress in his thesis. There is a significant relationship between the communication between the student and the thesis supervisor with the stress in his thesis at S 1 Nursing student.It was concluded communication students and lecturers stress affects students in the thesis. Expected supervisor can divide their time in serving the students in the process of thesis guidance.
EFFORTS TO IMPROVE TEACHERS IMPLEMENTING CAPABILITIES THROUGH CHARACTER EDUCATION TECHNICAL SUPERVISION GROUP AT STATE ELEMENTARY SCHOOL 17 PANYAKALAN DISTRICT OF SOLOK DISTRICT KUBUNG
Authors: Mulyadi Mulyadi
Published: February 2022

Abstract Character education is one very important aspect is developed in school. The development of character education has become a national agenda and should be integrated into the curriculum. Based on the beginning observations of the teachers of State Elementary School 17 Panyakalan District of Kubung indicated the ability of teachers to implement character education is still low. This phenomenon is closely linked to the suspected teachers who still lack understanding about concepts of character education, how to integrate character values ​​into the curriculum has not been mastered, as well as the assessment and follow-up has not been understood. This research is a school action aimed to reveal one of the techniques that can be used to improve the ability of teachers to apply character education. The technique that used is the technique of group supervision. namely: providing guidance to the teacher in groups. Researchers conducted a guidance to teachers in small groups and teachers collaborate and cooperate. Hypothesis actions proposed in this study is to use the technique of group supervision can improve the ability of teachers to apply character education at State Elementary School 17 Panyakalan District of Kubung. School action research subjects are all teachers civil servants and non-civil servants State Elementary School 17 Panyakalan District of Kubung are a total of 11 people. The procedure of research consisted of four stages: planning, action, observation, and reflection. Cycle performed in this study as much as two cycles. Each cycle carried out 2 times a supervision activities. Data were obtained from observations and the work in the form of a syllabus and lesson plans and then analyzed. School action research analysis results indicate that there is an increase in the ability of teachers to implement character education In addition, the teachers showed a positive attitude and high motivation to implement character education in the schools. The result of this research showed that ability of teachers are increase in applying the character education at State Elementary School 17 Panyakalan District of lemur can be done by using the group supervision. The conclusion of this study showed an increased ability of teachers to implement character education at State Elementary School 17 Panyakalan District of lemur through the technique of group supervision. This is evidenced by the increased activity of students while studying in cycle 1 and cycle 2.
INTEGRASI PENDIDIKAN KARAKTER DI SMP PONDOK PESANTREN MODERN NURUL IKHLAS KABUPATEN TANAH DATAR SUMATERA BARAT
Authors: Hadiyanto Hadiyanto
Published: February 2022

Abstract The study of integration of character education in Junior Secondary School Nurul Ikhlas Tanah Datar, West Sumatra is a joint research with the approach of a combination of quantitative and qualitative, aims to understand the efforts undertaken by the leadership of the boarding school and the principal to integrate character education or character values that are universal to the school management processes. Among the character values uniquely invested in modern boarding school Nurul Ikhlas are: Deepening Religious Sciences, the mole, Compliance, Modeling, Piety, Independence, Discipline, Simplicity, Tolerance, feel enough, Humility, Fortitude, Solidarity, Sincerity, Cling to religion, Society, Cleanliness.  The seventeenth character is jointly invested well for students to learn at school and when students receive education from boarding schools, to teachers and other education personnel. The uniqueness of Junior Secondary Boarding School Nurul Ikhlas in integrating character education into the educational process so as to produce quality graduates, an attraction for parents and prospective students to study at the boarding school.  This concern which contribute optimally to support both leaders and the head of the boarding school so that the educational process can be managed optimally.  This suggests the process of character education is not only optimal in boarding schools, but also in regular schools, both public and private that currently require it.
HUBUNGAN PERANAN KEPEMIMPINAN KEPALA SEKOLAH DENGAN KOMPETENSI PEDAGOGIK GURU DI SMK NEGERI 2 KOTA PADANG
Authors: Nellitawati Nellitawati , Boon Yusof Bin
Published: February 2022

Abstract This research about leadership role of headmaster and pedagogy competencies of teacher in SMK 2 Padang, and also to see the relationship between the two variables. Population are 72 teachers and 40 samples using proportional stratified random sampling technique. This research instrument is a questionnaire in the form of a Likert scale, a score of variable leadership role of headmaster 0.907 and pedagogy competencies of teacher 0.897 that  means instrument is reliable. Data were analyzed using product moment correlation, get r score = 0.33 > = 0.284 believed  r tabel standard 95%. Research has come to the conclusion that there are relationship between leadership role of headmaster with the pedagogy competencies of teacher in SMK Negeri  2 Padang.
Design of Web-Based Archive Management Information System
Authors: Syukhri Syukhri , Gusmayeni Pita
Published: February 2022

The advancement of information technology has now developed so rapidly, information has spread to the digital era, namely information that was previously processed in conventional ways, is now being managed with computer technology. Likewise with the archive management system for incoming and outgoing mail. The large number of incoming and outgoing letters every day at SMA PGRI 1 Padang makes the Administration section find it difficult to find files because they are looking for data one by one so that it takes quite a long time to search for archives, even archives often cannot be found because of the large number of archives. Realizing this, the title of Archival Management Information System Design at SMA PGRI 1 Padang West Sumatra Province using the Web-based CodeIgniter framework is expected to facilitate the Administration in the process of searching and distributing archives in a short time. The system development method used in this design is the Waterfall method. Because it is web-based, this application has the ability, the admin can manage the user, the Administrative Staff can add, edit, delete and save incoming and outgoing mail, the Head of Administration and the Principal can search for incoming and outgoing mail and can print the periodic letter report. . The results obtained from the implementation of this archiving application are to facilitate the Administration section in the computerized process of filing incoming and outgoing mail so that it becomes more efficient.
Visual Book as a Learning Medium of Islamic Religious Education Courses for Politeknik Elektronika Negeri Surabaya (PENS) Students
Authors: Murdaningtyas Citra Devi , Hapsari Anggun , Arifin Imamul
Published: February 2022

The Islamic Religious Education course, which is then abbreviated as PAI, is a compulsory subject for Muslim students that must be implemented in every university in Indonesia. This is stated in Law No. 12 of 2012 Article 35 Paragraph 3 concerning Higher Education. In its implementation, Politeknik Elektronika Negeri Surabaya (PENS) has given these courses to students. This course aims to shape students into human beings who believe and fear Allah SWT. and have noble character. On the other hand, an understanding of the subject matter of PAI is very important in order to realize this main goal. Based on the results of research entitled Questionnaire for Islamic Religious Education Courses at PENS, it was stated that 75% of the 40 respondents found it difficult to learn and understand some chapters due to the lack of visualization of the material and too many terms that were difficult to understand or memorize. Another problem found through this research is that the intensity of respondents' reading activities is still relatively low. Therefore, this research is expected to be able to increase understanding related to PAI courses through reading activities for PENS students by contributing in the form of making visual books as interesting PAI learning medium.
E-Jobsheet Based on Mobile Pocket Book as Digital Learning Resources (DLRs)
Authors: Samala Agariadne Dwinggo , Giatman Muhammad , Simatupang Wakhinuddin , Ranuharja Fadhli
Published: February 2022

This study aims to develop an E-jobsheet based on a mobile pocket book in the form of a digital pocket book on algorithms and basic programming courses. This research is a Research & Development (R&D) research with the Borg & Gall development model which consists of 10 stages, but in this research, the researcher limits it to producing an initial product in the form of an initial product or to the 5th stage, namely main product revision. The research instrument in collecting data used validation questionnaires, response questionnaires, and unstructured interviews to users during small-scale trials. The data analysis used in this research is descriptive data analysis with a quantitative approach. Based on the validation results from the media and material aspects, the overall product validity level is 85.46% with a valid category, the student response rate in a small-scale trial of the E-jobsheet is 86% with a very good category. So, it can be stated that the E-jobsheet based on the mobile pocket book that was developed is valid and suitable for further use on a wider scale.
PERTUMBUHAN KEGIATAN INDUSTRI PENGOLAHAN SKALA MIKRO DAN KECIL DI INDONESIA
Authors: Raharjo Jeff Royce , Setyaningrum Idfi , Djoemadi Firman Rosjadi
Published: February 2022

Sektor industri menjadi faktor utama pertumbuhan ekonomi terhadap perekonomian nasional sebesar 33,45%, dengan pertumbuhan yang secara segnifikan tersebut negara memiliki tekat untuk memperkuat potensi dan daya saing agar terus bertumbuh. Tujuan penelitian ini untuk mengetahui faktor apa saja yang dapat mempengaruhi performa dari industri pengolahan dalam skala usaha mikro dan kecil yang ditinjau dari kegiatan ekspor. Variabel yang digunakan dalam penelitian ini adalah Bentuk Badan Usaha, Pendapatan Dalam Setahun, Modal, Sumber Modal Utama, Kesulitan Industri Mikro dan Kecil, Kesulitan Bahan Baku, Penggunaan Internet, Konsumen Utama, Alokasi Pemasaran, Serta Konsumen dan Banyaknya Produksi Untuk Perusahaan. Data yang digunakan dalam penelitian ini merupakan data yang diambil dari publikasi Badan Pusat Statistik tentang Profil Industri Mikro dan Kecil 2019. Pengujian dilakukan menggunakan metode Two Step Cluster pada software SPSS 25. Penelitian ini memberikan hasil dua cluster sebagai berikut: Cluster 1 terdiri dari 31 provinsi, sedangkan Cluster 2 hanya 3 provinsi.
Cambios en precios relativos y bienestar en Argentina
Authors: Lozano Sabrina , Puig Jorge , Fernández Felices Diego Javier
Published: February 2022

Este trabajo analiza el efecto sobre el bienestar ocasionado por los cambios en precios relativos ocurridos en Argentina entre diciembre de 2016 y junio de 2019. A tal fin, se realiza una estimación actual de las características distributivas de los bienes utilizando la Encuesta Nacional de Gasto de los Hogares 2017-2018 en base a la metodología de Navajas (2004). Los resultados muestran una caída del bienestar social explicada principalmente por el fuerte incremento de precios relativos en los rubros electricidad y gas, comunicaciones, transporte y algunos alimentos. Las heterogeneidades en los patrones de consumo y en los cambios de precios relativos llevan a que la magnitud del efecto difiera entre regiones del país.
Citação e intimação via aplicativo de mensagens WhatsApp no âmbito do processo civil
Authors: Cavalli Maria Caroline , Galio Morgana Henicka
Published: February 2022

A citação e intimação são os atos processuais destinados a dar ciência ao réu do devido processo que tramita em seu desfavor e comunicar às partes sobre os atos praticados durante a tramitação do processo, respectivamente. Estes atos de comunicação processual estão previstos na lei processual civil, entretanto, verifica-se uma tendência na utilização do aplicativo de mensagens WhatsApp para a prática destes atos processuais de comunicação, sob o argumento de tornar o procedimento mais rápidos e econômicos, combatendo a morosidade processual. Assim, surgiu o questionamento: são válidas as comunicações processuais realizadas por meio do aplicativo de mensagens WhatsApp no processo civil? Para responder esta pergunta, foram analisadas doutrinas e legislação pertinentes ao tema, incluindo resoluções e portarias internas no âmbito do Tribunal de Justiça de Santa Catarina. A pesquisa utilizou o método de abordagem dedutivo, partindo da teoria de base processual civil sobre citações e intimações, para, em seguida, analisar o caso específico da realização de tais comunicações processuais por meio do aplicativo WhatsApp. As técnicas de pesquisa utilizadas consistem em pesquisa bibliográfica e documental. Por fim, concluiu-se que é válida a intimação das partes realizada pelo WhatsApp, desde que preenchidos os requisitos estabelecidos pelo CNJ e/ou outros, se houver regulamentação específica pelo Poder Judiciário estadual, entretanto, o mesmo não se aplica à citação. Sendo assim, deve prevalecer a formalidade da citação no processo civil, ainda que no âmbito do Juizado Especial.
Epidemia i choroba. "Miasto ślepców" José Saramago: od literackiej paraboli po (nowo)medialne adaptacje i rzeczywiste zachowania społeczne
Authors: Ogonowska Agnieszka
Published: February 2022

Celem artykułu jest ukazanie potencjału powieści José Saramago, zgodnie z ideą „tekstu literackiego w działaniu” oraz jego mocy performatywnej. Wykorzystano do tego trzy perspektywy, zwane w artykule kręgami wtajemniczenia: literaturoznawczo-kulturową, medioznawczo-komunikologiczną oraz socjologiczną. Dla każdej z nich wyodrębniono słowa kluczowe oraz ramowe lub wiodące zagadnienia. Zaproponowana w artykule perspektywa badawcza pokazuje, iż wyjście poza tradycyjne analizy literaturoznawcze czy językoznawcze skoncentrowane na tekście pozwala zaktualizować jego potencjał w różnych działaniach, z adaptacją i edukacją humanistyczno-społeczną na czele.
Tecnologias e letramentos digitais:
Authors: Beatrizoli Beatriz Oliveira de Almeida , Lynn Alves Lynn Rosalina Gama Alves , Andr´e Mattedi André Luis Mattedi Dias
Published: February 2022

Novas modalidades de leitura e escrita têm se tornado cada vez mais requisitadas para a produção de conhecimento no contexto contemporâneo. Assim, este artigo tem como objetivo analisar as formas de interação dos alunos dos Bacharelados Interdisciplinares da Universidade Federal da Bahia com o Zotero, que contribui com o letramento digital desses estudantes. Portanto, foi realizada uma pesquisa qualitativa utilizando questionário e observação participante para a produção de dados. Os resultados da pesquisa apontam a dificuldade dos alunos em se tornarem letrados em ambientes digitais, especialmente naqueles que exigem conhecimentos prévios de normatização que gerenciam os trabalhos acadêmicos como o Zotero.
O CINEMA NEONOIR ITALIANO E SUA ABORDAGEM EM L’ULTIMO CAPODANNO
Authors: Rossato Augusti Alexandre
Published: February 2022

A proposta deste artigo é a de verificar traços do cinema noir em um filme italiano que rompe com o período que na Itália é tradicionalmente compreendido como o do cinema noir clássico. Para além disso, a obra analisada, L’ultimo capodanno (Marco Risi, 1998), pode ser facilmente percebida como pertencente ao gênero comédia. No entanto, empreende-se aqui uma tentativa de orientar para um olhar mais complexo sobre ela, identificando-se elementos do cinema noir ou neonoir e situando-os em uma narrativa que a priori conduziria acentuadamente para uma outra noção de gênero. Como orientação metodológica, aponta-se a análise fílmica, destacando-se principalmente os autores Jacques Aumont e Michel Marie (2009), e Francis Vanoye e Anne Goliot-Lété (2009). Defende-se que L’ultimo Capodanno se trata de um filme neonoir, que rearranja elementos do noir clássico, tratados em condições particulares, contribuindo deste modo para uma nova alternativa de manifestação deste gênero em sua condição neonoir.
INDÚSTRIA CRIATIVA E JORNALISMO: UMA ANÁLISE DOS PORTAIS DIÁRIO ONLINE E O LIBERAL NOS SMARTPHONES
Authors: Figueiredo de Abreu Giovanna , Evangelista de Sousa Maíra
Published: February 2022

Os smartphones têm se configurado como espaços para a produção de conteúdos inovadores pela indústria criativa (BELOCHIO; FEITOSA, 2018). Nesse cenário, este artigo tem o objetivo de identificar, com foco na indústria criativa, de que forma os portais jornalísticos – Diário Online (Dol) e O Liberal – têm produzido conteúdos para os smartphones. De abordagem qualitativa, a pesquisa utilizou como metodologia a análise de conteúdo (CHIZZOTTI, 2000; BARDIN, 2006). As versões móveis dos portais foram avaliadas a partir de dez categorias: usabilidade, multimidialidade, hipertextualidade, participação, modelo de negócio, design responsivo, tactilidade, nivelabilidade, personalização e multisuporte. Verificou-se que os portais jornalísticos analisados não apresentam todas as potencialidades oferecidas pelos smartphones, existindo aspectos subutilizados que precisam ser melhor explorados.
AUDIOVISUAL COMMUNICATION IN CULTURAL SPACES
Authors: Guindani Joel Felipe , Urach Priscila Bicca , Sampaio Eloísa
Published: February 2022

This paper aims to reflect on the relationship between audiovisual communication and cultural spaces, specifically the Cultural Association of Bossoroca (ACB), located in the border region of Missões, in the town of Bossoroca. Theoretically, it proposes the elucidation of the notion of audiovisual communication related to the management of information in the context of digitalization and technological virtualization and as a communication process of the Creative Industry. As a methodology, this paper makes use of digital media observation, collection, and qualitative analysis. The field research starts from the observation and mapping of communication platforms and contents of the ACB, and ends by pondering audiovisual as an important communication process to the management of cultural spaces.
Applications of Inductively Coupled Plasma Mass Spectrometry (ICP-MS) in the Central Analytical Department of Ciba-Geigy
Authors: Baumann Heinrich
Published: February 2022

The present paper shows the potentialities of ICP-MS for the trace and ultra-trace analysis of different materials in an industrial laboratory. An overview is given on some applications of ICP-MS in the Central Analytical Department of Ciba-Geigy. The use of a He-MIP (Microwave
Induced Plasma) as an alternative to the Ar-ICP as an ionization source for the mass spectrometer is discussed.
Die Geschichte einer Acetalisierung und die überraschende Dimerisierung eines 1,3-Dioxan-4-ons zu einem Zwölfring [2-(tert-Butyl)6-(trifluoromethyl)-1,3-dioxan-4-on und 2,8-Di(tert-butyl)-6,12-bis(trifluoromethyl)-1,3,7,9-tetraoxacyclodecan-4,10-dion aus rac-,(R)- und (S)-4,4,4-Trifluoro-3-hydroxy-butansäure und Pivalaldehyd]
Authors: Beck Albert K. , Gautschi Markus , Seebach Dieter
Published: February 2022

All possible forms of 2-(tert-butyl)-6-(trifluoromethyl)-1,3-dioxan-4-one (rac, dextro- and laevoratatory of cis- and trans-isomer 2,3) are prepared and fully characterized. It is shown by DSC measurements that the racemic mixtures of both diastereoisomeric
dioxanones crystallize as racemates and not as conglomerates. Preparation of the dioxanone, of which the cis-isomer 2 is thermodynamically favoured, from pivalaldehyde and trifluoro-hydroxy-butanoic acid is more straight-forward with the enantiomerically pure acid than with the
racemic one: a poorly soluble, high-melting dimer 4 with a twelve-membered-ring structure, containing an (R)- and an (S)-molecule (Ci symmetry), is readily formed, even in the solid state, under the influence of traces of acid.
Structural Analysis of Monoclonal Antibodies with Top-down and Middle-down Electron Transfer Dissociation Mass Spectrometry: The First Decade
Authors: Fornelli Luca , Ayoub Daniel , Srzentic Kristina , Nagornov Konstantin , Kozhinov Anton , Gasilova Natalia , Menin Laure , Beck Alain , Tsybin Yury
Published: February 2022

Monoclonal antibodies (mAbs) are protein biotherapeutics with a proven efficacy toward fighting life-threatening diseases. Their exceptional healing potential drives the annual increase in the number of novel mAbs and other antibody-like molecules entering clinical trials and the number of approved mAb-based drugs. Mass spectrometry (MS) offers high selectivity and specificity for the potentially unambiguous identification and comprehensive structural characterization of proteins, including at the proteoform level. It is thus not surprising that MS-based approaches are playing a central role in the biopharma laboratories, complementing and advancing traditional biotherapeutics characterization workflows. A combination of MS approaches is required to comprehensively characterize mAbs’ structures: the commonly employed bottom-up MS approaches are efficiently complemented with mass measurements at the intact and subunit (middle-up) levels, together with product ion analysis following gas-phase fragmentation of precursor ions performed at the intact (top-down) and subunit (middle-down) levels. Here we overview our group’s contribution to increasing the efficiency of these approaches and the development of the novel strategies over the past decade. Our particular focus has been on the top-down and middle-down MS methods that utilize electron transfer dissociation (ETD) for gas-phase protein ion fragmentation. Several approaches pioneered by our group, particularly an ETD-based middle-down approach, constitute a part of commercial software solutions for the mAb’s characterization workflows.
Novel Time-of-Flight Residual Gas Analyzer (TOF-RGA) for in situ Real-time Process Monitoring
Authors: Gasc Sébastien , Hofer Lukas
Published: February 2022

Sensitive gas analyses, in particular in industrial processes, are nowadays performed either via spectroscopy or using quadrupole mass spectrometers; the first method provides a fast but indirect measurement, whereas the second provides in situ measurements of only one species at a time. In this article, we present a novel time-of-flight residual gas analyzer (TOF-RGA) built by the Swiss company Spacetek Technology AG, and show the results of measurements such as the characterization of the FC5311 calibration compound, the detection of naturally abundant noble gases in air, the measurement of a noble gas mixture in the ultra-high vacuum facilities of CERN, and measurements acquired in a X-ray Photoelectron Spectroscopy facility in Germany, to demonstrate the capability of this new TOF-RGA to compete with already existing techniques for the monitoring of the composition of gases in real time (10 times per second), at high resolution (m/?m = 1 200 measured at m/z 132), and with a high sensitivity at ppb level.
Time-Of-Flight Mass Spectrometers Made in Switzerland: Examples of Mobile Applications
Authors: Hutterli Manuel , Pospisilova Veronika , Gonin Marc
Published: February 2022

Over the past decade, the technical requirements of analytical instrumentation have continuously risen driven by the demand for increasingly complex and demanding applications. TOFWERK, a Swiss company with the headquarters in Thun, has been at the forefront of this development by producing modular and ruggedized Time-Of-Flight Mass Spectrometers (TOFMS). They are often used to replace quadrupole mass analysers with more powerful TOF mass analysers. Starting with first customers in atmospheric sciences, TOFWERK TOFMS are now used across a wide range of research areas and lately also in industry. Here we present an overview of mobile applications in which Tofwerk TOFMS are in operation while moved around in space.
The Conceptual Algorithm of the International Multimodal Transport (CAIMT)
Authors: Miler Ryszard Karol , Kuriata Andrzej
Published: February 2022

The presented paper comes as a summary of a theoretical work presenting an original algorithm describing International Multimodal Transport (IMT) mechanisms and processes. Since containers appeared in early 1960s on the regional, and later on, on global scale in logistic operations, the IMT has become the fastest growing combination of an international through-transport. With use of various modes of transport IMT has significant influence on global trade development. Due to its characteristic the IMT process is exposed on the global unitization, standardization, safety, security and economization (optimization) challenges. Thus, there is a need for scientific approach in building a standardized conceptual model of IMT referred in this paper to CAIMT. CAIMT is an original, deterministic algorithm, presented in the block notation, identifying typical procedures as a logical continuation of the programmed sequence of the basic IMT operations. The suggested CAIMT has a potential in further standardization of IMT procedures and can be scientifically developed through the modeling of the IMT processes and safety/security procedures. In addition, in terms of empirical aspects, algorithmization of the main IMT processes can lead to their application in the various expert systems. Summing up, this method (CAIMT) comes as an optimal instrument that can be utilized in order to build further pillars for IMT development, standardization and optimization.
SWEDISH URBAN TRANSPORT MODEL POWERED BY BIOMETHANE
Authors: Żółtowski Andrzej
Published: February 2022

In the recent years, European Community has been implementing a plan to increase the share of renewable fuels used for energy production and powering vehicles. It aims to partially reduce the dependence on crude oil imports and reduce CO2 emission. Particularly interesting are the achievements of Sweden against this background, for which the European Commission has set the highest value of the indicator, and to implement which Sweden adopted unconventional solutions across Europe. One of them is the plan to eliminate by the 2030 fossil fuels from the urban transport, and one of the fuels that is to replace today still widely used diesel oil, would be biomethane. The article describes the reasons and circumstances which made Sweden use biomethane to power buses used in urban transport on a very large scale, in comparison with other European countries. The article shows the characteristics of this fuel, the method of its production and application prospects.
Effective protection of information systems and networks against attacks in the era of globalization
Authors: Witczyńska Katarzyna
Published: February 2022

The problem of ensuring the security of networks and computer systems of transnational companies is one of the most important issues of modern computer science. In scientific centers around the world, numerous studies are carried out to ensure the security of operating systems and application programs. The aim of the work is to provide theoretical and practical knowledge related to threats, security methods and the latest trends in effective protection of networks and information systems against attacks.
Changes versus Organization Staff
Authors: Rawłuszko Kazimierz
Published: February 2022

The article presents selected problems accompanying change management, with particular emphasis on possible behaviours on the part of staff. By emphasizing the possible reactions of employees to changes in the organization, possible ways of overcoming barriers that may appear in the process of change were emphasized. The role that should be played by the manager, who during the shift must be a leader and a leader who inspires staff, is highlighted.
Decision-making process in manager’s work
Authors: Stachelek Dariusz
Published: February 2022

The article deals with the decision-making process in the efficient operation of a manager. The author presented a model of the decision-making process focusing on managers who nowadays will have to make more and more difficult strategic decisions.
Failure Mode and Effect Analysis of Air Cargo Freight Services Provider
Authors: Sładkowski Aleksander , Cieśla Maria
Published: February 2022

In the theoretical part, this article presents the basic conditions for the organization of air transport cargo divided into different types of cargo shipments. Then an analysis of the Polish market of air cargo shipments is presented, taking into account the type of companies, airlines and airports that support them. In the research part, an FMEA analysis of an entity providing air cargo transport organization services was made, presenting several disadvantages and possible remedial actions that contribute to the improvement of the quality of services.
The Supplier Selection Process in Regional Terms – Case Study Analysis
Authors: Galińska Barbara , Pisarek-Bartoszewska Renata
Published: February 2022

The article presents the supplier selection procedure, which is one of the key elements of the whole procurement process, carried out in each business entity. Particular attention was paid to the regional aspect of the issue. It has also been presumed that in the case study, only local suppliers will be taken into account. Such assumption (including close distance between potential supplier and a company) fosters e.g. reduction of costs and delivery time, enhances all supply chain and enables implementation of modern management concepts. In times of strong competition, all these aspects have become particularly important. In the phase of computational experiments, which aimed at ranking and selection of the most desired supplier in the case study, multiple criteria ranking methods - Electre III/IV and Promethee II have been applied.
International Transport Corridors Functioning Efficiency in the Digital Economy Conditions
Authors: Isaienko Volodymyr , Bugayko Dmytro , Hryhorak Mariia , Ovdiienko Oksana
Published: February 2022

The problem that is taken under consideration in the following article concerns the implementation, use and effectiveness of virtual work in the supply chain in e-economy. Any solution concern employee mobility or the use of mobile technology are due to growing market competition and constant search for new solutions that may enable the companies in the supply chain to be more efficient than the competition. In the supply chain the E-business creates for the companies new challenges they have to face. One of the possibilities to improve your business in the supply chain is to use virtual work. The new challenge facing the e-economy needs to be met. The aim of the article is to refer the virtual work, that is used by selected links in the supply chain to meet e-economy requirements, identify the key factors that characterize e-economy and refer them to the possibilities and benefits of using virtual work in the supply chain.
Diversity of logistics centre concepts in Europe
Authors: MIndur Maciej , Turoń Katarzyna , Sierpiński Grzegorz
Published: February 2022

The article discusses logistic centres in Europe, legal changes and directions for their development in the European Union that has led to an increased cross border flow of goods and the need to continue the process. The article identifies major features of logistics centres and presents a comparison of various types of conceptual objectives for logistics centres in Europe. The analysis has been used to develop a list of features collated with the variety of concepts and current market requirements in relation to such issues as sustainable development and corporate social responsibility.
The determination of potential locations for hotel and service facilities in relation to the transport system - logistic approach
Authors: Mindur Maciej , Celiński Ireneusz , Sierpiński Grzegorz
Published: February 2022

The existing space distribution of hotel and service facilities in different places in the world is mainly the result of natural organic growth. Such facilities were built in areas of actual and/or potential demand, provided adequate financial resources and land were available. Additionally, an important factor was also the availability of technical infrastructure, including, in particular, transport. Sometimes those facilities were built without any detailed spatial analysis of their locations. It can be concluded that planning of hotel and service facilities lacked clear and accurate methods as well as analytic tools. The main reason was the lack of relevant databases. Along the development of Information and Communication Technologies (ICT), information tools started to be used in nearly every area. It should be noted that the development of the hotel and service base can be significantly promoted while using modern ICT solutions. In their article, the authors, among others, propose to use trip planning tools backed by Big Data. A trip planner can be used to collect data that help to determine the location of hotel and service facilities (e.g. hotels, guest houses, motels, leisure, recreation and restaurant facilities). The article presents the case study from the Upper Silesia conurbation, Poland. The use of Big Data allows to select locations of investment corresponding to actual tourist travel needs, especially that every year tourism becomes an increasingly important sector of the national economy in many countries.
The Evolution of a High Productivity Urban e-Commerce delivery vehicle using Australian Performance Based Standards
Authors: Hassall Kim , Thomson Russell , Cowell Ken
Published: February 2022

The introduction of High Productivity Vehicles (HPVs) in Australia, through the Performance Based Standards (PBS) scheme, was predicated on new mechanical engineering standards that were mandated especially for these new vehicles. These standards improved vehicle stability, general performance and safety, especially safety. Two national surveys showed both massive safety and productivity benefits compared to conventional Australian road freight fleets. The first Australian PBS vehicles operated under permits from 1997 but the formalized Australian scheme was implemented in 2006. So arguably the introduction of HPVs under permit and now under a formal regulatory PBS framework has allowed some 20 years of research observations. However, only one major type of single rigid, high productivity truck, without a trailer, has been active in an urban environment as a pilot, over that time. This paper examines this special urban High Productivity Vehicle which could be exceptionally useful for the urban freight task in many countries should they ever adopt it.
The use of the EOQ model in inventory management in the supply chain on the example of Bahlsen Polska
Authors: Paluch Waldemar
Published: February 2022

The article presents the theoretical basis of the EOQ (economic quantity order) model, which allows you to optimize the size of the order so as to minimize the cost of frozen capital. The next part presents the results of implementing the model at Bahlsen Polska, assuming that it does not receive any discounts from suppliers in relation to the size of the order. This assumption can be excluded in the case of the functioning of the disposition system, carried out taking into account large contracts with the supplier. Optimization in this situation does not apply to the quantity in the contract, but only to a single call, which is information for the supplier who must deliver a certain amount of goods and at the same time reduce the balance appearing in the contract.
Performance management in logistics companies – two-dimensional approach
Authors: Comporek Michał
Published: February 2022

The main aim of the article is to emphasize the problem of selecting performance management (PM) indicators in logistics companies. This issue is particularly significant, because the proper selection of PM measures affect on: the effectiveness of the implemented performance measurement system, the nature of information provided to its individual stakeholders, the system of interconnections within the organization, and often even the efficiency of the entire business entity on the market. However, paper draws attention to the potential of deliberately distorting the reported company results by the management team. Hence the secondary goal of the article is to select various tools and/or techniques, which may be helpful in assessing the quality of reporting PM - in relation to the real earnings management (REM). The applied research methods are based on a critical analysis of the literature on the subject matter.
The development of bike-sharing systems in Poland. The study of Wavelo system in Kraków
Authors: Świgost-Kapocsi Agnieszka
Published: February 2022

The interest in bike transport in Polish cities and towns has been growing systematically in the recent years. A great number of local authorities take various actions to support the development of cycling systems. They make an effort to develop a cycling infrastructure – bike lanes, Bike&Ride type of parking, bike stands and advanced stop lines. An increased interest in bike-sharing systems is visible as well. Apart from that, the authorities implement policies and take other actions which make cycling in a city more convenient. The aim of the article is to characterize the experience of Polish cities in the area of bike transport support, with a special attention to bike-sharing systems. The article presents a comparison of 38 city bike systems. In addition, the Wavelo system in Kraków was studied in detail. Wavelo city bike system is very popular among citizens of Kraków. Despite relatively high prices and the lack of free minutes, the number of system users is growing. A large number of docking stations and their locations make bikes more accessible to citizens. Moreover, Kraków's authorities take action to develop a proper bike infrastructure which increases the interest in cycling as a transportation system.
PARAMETER OF COOPERATION OF COMPOSITE COMPONENTS IN VIEWS ABOUT VERTICAL WALL FROM REINFORCED SOIL
Authors: Zamiar Zenon , Surowiecki Andrzej , Saska Piotr
Published: February 2022

The publication considers reinforced soil in relation to the construction of retaining walls in communication construction. The basic elements determining the cooperation of reinforcement inserts with the ground centre are discussed, depending on the features characterizing the components of the composite. The method and selected results of tests performed on a massif model with a vertical wall made of non-cohesive ground have been presented. A calculation example is given concerning the internal dimensioning of the reinforcement of the considered massif model, assuming the work of inserts without slipping in the ground centre. The concept of reinforcement co-operation indicator with the ground centre was introduced and a dependence to calculate its value was developed. The values ​​of co-operation indicators: general and partial, concerning individual measurement levels of the model have been presented appropriately.
A brominated carbazole with antibiotic adjuvant activity displays pleiotropic effects in MRSA’s transcriptome
Authors: Viering Brianna , Cunningham Taylor , King Ashley , Blackledge Meghan , Miller Heather
Published: February 2022

Methicillin-resistant Staphylococcus aureus (MRSA) is a major threat to human health, as the US mortality rate outweighs those from HIV, tuberculosis, and viral hepatitis combined. In the wake of the COVID-19 pandemic, antibiotic resistant bacterial infections acquired during hospital stays have increased. Instead of designing and deploying new antibiotics which MRSA would quickly develop resistance to, adjuvants are a key strategy to combatting these bacteria. We have evaluated several small molecule antibiotic adjuvants that have strong potentiation with β-lactam antibiotics and are likely inhibiting a master regulatory kinase, Stk1. Here, we investigated how the lead adjuvant exerts its effects in a more comprehensive manner. We hypothesized that the expression levels of key resistance genes would decrease once cotreated with a β-lactam antibiotic (oxacillin) and the adjuvant (compound 8). Furthermore, bioinformatic analyses would reveal biochemical pathways enriched in differentially expressed genes. RNA-seq analysis showed 176 and 233 genes significantly up and downregulated, respectively, in response to cotreatment with compound 8 and oxacillin compared to oxacillin alone. Gene ontology categories that were significantly enriched among downregulated genes involved phosphotransferase systems. Most of the biochemical pathways enriched with significantly downregulated genes involved carbohydrate utilization, such as the citrate cycle and the phosphotransferase system. One of the most populated pathways was S. aureus infection. Results from an interaction network constructed with affected gene products supported the hypothesis that Stk1 is a target of compound 8. This study revealed a dramatic impact of our lead adjuvant on the transcriptome that is consistent with a pleiotropic effect due to Stk1 inhibition. These results point to this antibiotic adjuvant having potential broad therapeutic use in combatting MRSA.
Syntheses and activities of indol-2-ylidene-ligated ruthenium-based olefin metathesis catalysts
Authors: Kim Minseop , Kim Hyunho , Kim Seyong , Hong Sukwon , Lee Eunsung
Published: February 2022

Here we report a new family of indol-2-ylidene (IdY)-ligated Ru-based olefin metathesis catalysts (Ru−IdY) and their X-ray crystal structures which show a unique conformation of the ruthenium environment. Catalytic activities of Ru−IdY catalysts were investigated for ring-closing metathesis, ring-opening metathesis polymerization, and ethenolysis, which show excellent turnover numbers (TONs).
Umpolung AlaB Reagents for the Synthesis of Non-Proteogenic Amino Acids, Peptides and Proteins
Authors: Zhu Feng , Miller Eric , Powell Wyatt , Johnson Kelly , Beggs Alexander , Evenson Garrett , Walczak Maciej
Published: February 2022

Non-proteogenic amino acids and functionalized peptides are important motifs in modern drug discovery and used as mechanistic tools in chemical biology. Here, we show that functionalized amino acid synthons in the form of AlaB can serve as universal building blocks in the synthesis of a diverse collection of modified amino acids, peptides, and proteins. First, we develop the synthesis of AlaB from redox-active esters of aspartic acid resulting in a series of beta-boronoalanine derivatives. Next, we show that AlaB can be integrated into automated solid-phase synthesis of oligopeptides and proteins. AlaB is compatible with common transformations used in preparative peptide chemistry such as native chemical ligation and radical desulfurization as showcased by total synthesis of boronoalanine-modified ubiquitin (Phe4-AlaB). Furthermore, AlaB reagents participate in Pd-catalyzed reactions, including C(sp3)-C(sp2) cross-couplings and macrocyclizations. Taken together, AlaB synthons are practical reagents to access non-natural amino acids, modified peptides, proteins, and in the synthesis of cyclic/stapled peptides.
Aryl Fluorosulfate-Based Inhibitors that Covalently Target the SIRT5 Lysine Deacylase
Authors: Bolding Julie E. , Martín-Gago Pablo , Rajabi Nima , Gamon Luke F. , Hansen Tobias N. , Davies Michael Jonathan , Olsen Christian Adam
Published: February 2022

The sirtuin enzymes are a family of lysine deacylases that regulate gene transcription and metabolism. Sirtuin 5 (SIRT5) hydrolyzes malonyl, succinyl, and glutaryl epsilon‐N‐carboxyacyllysine posttranslational modifications and has recently emerged as a vulnerability in certain cancers. However, chemical probes to illuminate its potential as a pharmacological target has been lacking. Here we report the harnessing of aryl fluorosulfate-based electrophiles as an avenue to furnish covalent inhibitors that target SIRT5. Alkyne-tagged affinity-labeling agents recognize and capture SIRT5 in cultured HEK293T cells and can label SIRT5 in the hearts of mice upon intravenous injection of the compond. This work demonstrates the utility of aryl fluorosulfate electrophiles for targeting of SIRT5 and suggests this as a means for the development of potential covalent drug candidates. It is our hope that these results will provide a key reference for future studies investigating SIRT5 and general sirtuin biology in the mitochondria.
PCB DESIGN OF A SERVO MOTOR CONTROLLER UNDER STRICT COST CONSTRAINS –THERMAL AWARE COMPONENT LAYOUT
Authors:   IMST, POLITEHNICA University of Bucharest, Romania, Burducea Sorin , Zapciu Miron ,   IMST,POLITEHNICA University of Bucharest, Romania
Published: February 2022

This work comes within the scope of developing an automated linear axis that will be used in a novel production machine. The axis needs precise control over the linear movement, calling for a servo-controlled motor. There are many types of motors that can be used, starting from inexpensive stepper motors, up to expensive and performant multi pole permanent magnet synchronous motors. The project calls for a servo drive that will be able to deliver a power output within 200 to 600 Watts, with an efficiency of over 80%. Brushless DC motors offer many possibilities within this range of powers with outstanding price/performance ratios. Open source projects like TinyMovr, Vesc and ODrive propose highly performant software stacks that are used extensively within robotics communities. These open software solutions need adequate hardware platforms to perform. The scope of this work is the description of the steps taken to design the printed circuit board on which the ODrive servo motor control firmware can be implemented, from the point of view of the thermal effects of its components. Under normal cost constrains, the PCB would have been implemented using a minimum of four copper layers. It is the aim of this design to fulfil a stricter cost constrain that only allows for a two layer board to be used.