bluuebunny/crossref_metadata_2025 huggingface dataset:
SOCIAL POTENTIAL OF HIGHER EDUCATION TEACHERS OF THE THIRD AGE: PROBLEMS AND NEW CHALLENGES
Authors: SHUKLİNA Elena , PEVNAYA Mariya
Published: February 2020

Introduction
Russian teachers of the third age are a social group that is currently in a difficult and ambiguous situation. On the one hand, raising the retirement age in Russia sets them the task of further professional development. On the other hand, the level of professional requirements associated with increasing the competitiveness of Russian higher education in the global educational space is sharply increasing. The purpose of the article is to answer the question - how the accumulated social potential of the third age's teachers allows them to adapt to new conditions, to increase the level of competitiveness, to act as a factor in the development of the University teaching community and higher education in general.

Materials and methods
The article is based on the materials of research team in the Ural Federal University (2017-2019). The article uses quantitative data of the mass survey of teachers in the Ural Federal district, implemented by the method of questioning. The population is 51 University of the Ural Federal district. Quota sampling was implemented in the study. The volume of the teachers' sample is 810 people. Social community of the third age's teachers was 38.5% of the total sample.

The results of research

The social potential of University teachers was considered in the context of the following structural elements: professional qualification, innovation, cultural, civil. Teachers of the third age have higher professional and qualification potential (qualification and status characteristics) than other age groups. The innovative potential realized in research activity and educational process is also high. This applies to innovation activity implemented in research projects and scientific communication. Their cultural practices are quite diverse, and the activity of cultural consumption is even higher than that of colleagues of other age groups. Civic activity of the third age's teachers is manifested in various forms of public participation, implemented through interaction with authorities of different levels and public organizations. The specificity of their civic activity is the implementation of expert functions that require high qualification, which has this group of teachers.
At the same time, the teaching community of the third age notes the lack of sufficient institutional conditions for effective development, manifested primarily in the low level of social protection in the professional sphere.

General conclusions

University teachers of the third age have sufficient adaptive potential in the new challenges of the social environment. At the same time, the basic problem of their development is the creation of institutional conditions for professional activities and the effective realization of their social potential.

Keywords
Educational reforms, university teachers, teaching community, public participation, higher education, third age
THE CADETS AND THE REASONS FOR THEIR DROP-OUT OF THE NATIONAL MILITARY UNIVERSITY
Authors: Terziev Venelin , Bogdanova Margarita , Kanev Dimitar , Georgiev Мarin
Published: February 2020

The goal of the present study is to reveal the essence of the reasons that lead to cadets’ drop out of the All-Army Faculty of National Military University and to propose actions for their impact reduction.
In order to achieve one of the sub-goals of the present study, namely to uncover the essence of the reasons that lead to drop off of cadets from the All-Army Faculty, it is necessary to take into consideration the trainees’ opinion, to outline the achievements and the disadvantages of the overall organization of living and studying in the National Military University from their point of view.
Keywords: drop-out, cadets, education, National Military University.
USE OF INTEGRAL INDICES IN THE ASSESSMENT OF BUCСAL CYTOLOGY IN HEALTH AND IN THE ORAL CAVITY PATHOLOGY
Authors: Bazarnyi V. V. , Polushina L. G. , Maksimova A. Y. , Svetlakova E. N. , Sementsova E. A. , Nersesian P. M. , Mandra Yu. V.
Published: February 2020

Cytological analysis of buccal epithelium (BE) - the buccal cytogram allows to select about 20 parameters reflecting cytogenetic, inflammatory, proliferative and other disorders in epithelial cells used for biomonitoring and laboratory diagnostics. In order to simplify and increase the information content of this study, we conducted a comparative analysis of various integral indices when interpreting the buccal cytogram. 40 practically healthy volunteers, 35 patients with chronic periodontitis, 22 patients with chronic gingivitis and 20 patients with partial loss of teeth were examined. The obtained data revealed an increase in the degree of disorders of proliferation and apoptosis, their ratio as the inflammation increased from gingival tissue lesions to inflammation periodontal tissue. In assessing the condition of the mucous membranes in chronic gingivitis, the apoptosis index turned out to be more informative.In chronic periodontitis the index of cytogenetic disorders is indicative. In this category of patients, the accumulation index of cytogenetic disorders did not have any advantages over the others, and the reparative index was less informative.
DETERMINATION OF SOME INDICATORS OF IMMUNITY AND LIPOPEROXIDATION IN THE ORAL FLUID IN PERSONS WITH A LOW VITAMIN D LEVEL
Authors: Karavaeva T. M. , Fefelova E. V. , Maximenya M. V. , Putneva A. S. , Fedorenko E. V. , Tereshkov P. P.
Published: February 2020

Oral fluid is a unique biological environment, containing a wide range of substances, coming from local and systemic sources, which makes it possible to use it as an object for assessing pathological changes in the body both at the local and systemic levels. In comparison with the traditional method of blood analysis, the advantage of evaluating the parameters of the oral fluid is the non-invasive of this method of obtaining material. All patients underwent oral fluid sampling using special plastic containers with a swab, which facilitate the selection of material, eliminating the penetration of mucin into a clean test sample, which helps to obtain more accurate analysis results.The amount of secretory IgA, lipopolysaccharide-binding protein (LBP), TBA-active products, the level of total antioxidant activity in the oral fluid in individuals with a low level of 25(OH)D before and after taking the native solution of vitamin D “Aqua Trim” were determined. The concentrations of secretory immunoglobulin A, lipopolysaccharide, binding protein and the level of total antioxidant activity are reduced in the oral fluid of people with vitamin D deficiency, but the number of intermediate products of lyoperoxidation increases. The course intake of the native solution of vitamin D (International Nonproprietary Name - Colecalciferol) normalizes the functioning of the immunity of the oral cavity and restores the balance of the “lipid peroxidation-antioxidants” system.
EXPERIENCE INTRODUCTION OF QUANTITATIVE ANALYSIS OF CHIMERISM AFTER ALLOGENIC STEM CELL TRANSPLANTATION BY REAL-TIME PCR WITH INDEL POLYMORPHISMS
Authors: Cheranev V. V. , Loginova M. A. , Kutyavina S. S. , Smirnova D. N. , Zorina N. A. , Minaeva N. V. , Paramonov I. V.
Published: February 2020

Using data obtained from domestic and foreign sources, we formed a set of primers and fluorogenic probes for analyzing twenty-six specific sequence polymorphisms and one reference gene. In the course of evaluating the effectiveness of real-time PCR, using the example of one of the markers (S01a), we obtained the optimal amount of DNA per reaction (70 ng), providing a resolution of at least 0.1% of the method with the ability to estimate linear chimerism. Formed panel of primers for genetic polymorphisms - InDel has a high degree of informational content for donor-recipient pairs of Russia. From January 2018 to June 2019, a quantitative assessment of the level of linear (CD3 +, CD34 +) and general chimerism was carried out for 28 patients of the clinic of the Institution. Finally, we analyzed patients who received allografts and present 4 different clinical situations that illustrate the informativity level of this method.
Evaluación de un techo verde bajo eventos de precipitación sintéticos para caracterizar el comportamiento del flujo por escorrentía
Authors: Rodríguez-Bejarano Emmanuel , Villagra-Mendoza Karolina
Published: February 2020

Techos verdes se refiere a la práctica de recubrir con una capa vegetal el techo de una estructura. A pesar de que esta estructura ha formado parte del paisaje arquitectónico característico de las tierras del norte afectadas por crudos inviernos hoy en día se ha presentado con gran auge en la arquitectura moderna. Su importancia, desde el ámbito hidrológico, radica en la capacidad que poseen para modificar el comportamiento hidrológico de un techo, de una zona y, por tanto, de una cuenca. Con el fin de cuantificar este comportamiento característico de un techo verde se llevaron a cabo una serie de pruebas con diferentes intensidades en un simulador de lluvia previamente calibrado, utilizando un techo verde de 3 metros cuadrados y eventos de precipitación desde 8 hasta 36 mm/h. Se cuantificó el volumen de agua de lluvia despejado por cada una de las capas que conformaron el techo verde. De esto se derivó que el tipo de sustrato instalado es un factor primordial para estimar el comportamiento hidráulico de la estructura ya que esta depende enteramente de la capacidad de conducción hidráulica del sustrato instalado para evitar la conformación de anegamientos en la superficie, aunado a esto, se encontró que las variaciones en la pendiente de instalación e intensidad de evento de precipitación no causaron una variación drástica sobre la curva de comportamiento del techo verde, pero sí en el volumen entregado por cada una de las capas que lo conforman.
Mejoras en el desempeño de la línea de producción 560A DA utilizando herramientas del sistema de producción Toyota
Authors: Monarca-Ugalde Stacy Zulay , Espinoza-Gutiérrez Carlos
Published: February 2020

El estudio en la empresa “A” se realiza en una compañía líder de fabricación de equipos electrónicos para automóviles, principalmente en sistemas de seguridad y de audio, localizada en Málaga, España. El estudio consistió en mejorar la línea de producción 560A DA (ensamble de radio para el nuevo modelo de automóvil que lanzará Toyota en el 2018) mediante el uso de herramientas de lean manufacturing.

Se analiza la línea para evaluar los principios de lean manufacturing y encontrar oportunidades de mejora. Al iniciar el estudio el desempeño del balance de línea con 8 operadores era de 72,72% y cada trabajador producía 30 unidades por turno de trabajo.

Al eliminar mudas, disminuir desplazamientos y mejorar el ciclo de trabajo del operador se logra balancear la línea a 6 operarios aumentando el desempeño de la línea a 84,20% y cada operador produce 33 unidades por turno de trabajo. Se analiza el puesto de trabajo mediante la herramienta “strike zone” con el fin de verificar que las herramientas e insumos se encuentran al alcance del trabajador. Además, se efectúa un estudio detallado de los ciclos de trabajo para así clasificar las operaciones en actividades que agregan y no agregan valor.

Durante el estudio, se identificó que la estación de prueba “Application” era causa de retrasos en el ciclo de trabajo del operador. Para concluir, se desarrolla una propuesta de ampliación de capacidad; la cual se aprueba para ser implementada en el mes de noviembre dado un aumento en la demanda de radios. El takt time para la línea ampliada sería de 80 segundos y según la propuesta el desempeño de la línea se espera sea de 95,51%.
Evaluación de pérdidas de alimento en lechuga (Lactuca sativa) durante las fases de precosecha, cosecha y comercialización bajo un sistema de cultivo orgánico y uno convencional
Authors: Castro-Granados Jonathan , Brenes-Peralta Laura Patricia , Campos–Rodríguez Rooel , Calderón-Cerdas Rubén Alfonso , Gamboa-Murillo Marianella
Published: February 2020

Las pérdidas de alimentos constituyen un tema clave por tratar al generar impactos negativos en la sociedad, la seguridad alimentaria, el medio ambiente y la economía de los sistemas agroalimentarios. Por esto han surgido iniciativas como SAVE FOOD ®; y de la cual nació el presente trabajo, con el fin de entender la cantidad y causa de pérdidas alimenticias en alimentos como la lechuga (Lactuca sativa), en fases de siembra, cosecha y comercialización de dos sistemas productivos: uno orgánico y otro convencional, en Costa Rica.

Para la fase de siembra a cosecha, el estudio mostró una pérdida del 2% en el sistema de producción convencional, y un 6% para el sistema orgánico. En el caso de la fase de cosecha a acondicionamiento se encontró un porcentaje de pérdida alimenticia para el sistema convencional del 25% y para el sistema orgánico un 33%. Finalmente, en la fase de acondicionamiento a comercialización, el porcentaje de pérdida alimenticia fue del 13% se para el sistema convencional, y 1% para el sistema orgánico.

Se infirió que estas pérdidas responden a causas como las malas prácticas agrícolas y de manufactura, representadas en la observación de daños de tipo entomológico, patológico y mecánico, así como la planificación y administración deficiente en pronósticos de producción y demanda.

Entre las soluciones, se sugieren un mejor control de enfermedades y plagas en finca, un mejor manejo por parte de los operarios del producto durante todas las fases de producción, al igual que una mejor estimación de la demanda.
THE STUDY OF THE INDONESIAN PRAGMATIC PARTICLE SIH
Authors: Rofiq Zainur
Published: February 2020

Indonesian is a relatively particle-rich language used mostly in casual speech. However, the study on the pragmatic functions of the language is very few and indebted much solely to the works of Ikranagara (1975), Sari (2008), and of Wouk (1998 & 2001). The present study aims to need to extend other functions of the particle sih in particular providing wider range of pragmatic functions than the previous work did. The data of the stuy derived from YouTube videos of live Indonesian unscripted talk show; and thus the conversations occur naturally during the program. The results reveal that marking an interrogative statement with sih following WH-words implies that the speaker emphasizes his main inquiry (e.g. ‘where’ emphasizes location) and urges the recipient to answer appropriately. Further, the study extends Sari (2008) and Wouk’s (2006) findings that sih is not only used to emphasize the topic or main point of WH-interrogative statement, but also it applies to declarative statement.
The Correlation between the Use of Social Media and Academic Writing Mastery of the English Education Students
Authors: Sari Rizky T , Hayati Rita , Suganda Lingga A
Published: February 2020

The objectives of this study were to find out: (1) the social media which is the most frequently used by the English Education Study Program students, (2) the correlation between the use of social media and academic writing mastery of the students, and (3) the contribution between the use of social media and academic writing mastery of the students. Thirty five students were chosen as the sample by using purposive sampling method. The data were collected through questionnaire and documentation. Pearson Product Moment Correlation Coefficient was used to analyze the obtained data. The result showed that there was a significant correlation between the use of social media and academic writing mastery of students of English education study program (
L2 teachers' knowledge of L2 learners’ listening and oral interpretation problems: Any correspondence?
Authors: Sadeghi Karim , Rahimi Mohammad Ali
Published: February 2020

The study was aimed at comparing learners’ knowledge of their listening and oral interpretation problems with their teachers’ perception and knowledge of the same problems. Fifty two learners in company with their three instructors participated in the study. The study tapped the students’ reflections on cognitive, affective and linguistic factors impinging on listening and oral interpretation processes and teachers’ perception and knowledge of the same real time listening and interpretation tasks. Introspection techniques, observation and interviews were the main techniques of data collection. Data analysis revealed many congruencies between the learners and their instructors in terms of the listening experiences and perceptions. They included such themes as ‘ineffective strategy of focusing on words’, ‘speedy delivery’, ‘difficulty level of the material’, ‘accent effect’ and ‘parsing problem’. However, some discrepancies were also identified with regard to such core themes as ‘modality’ and affective issues such as ‘stress’, ‘sense of fatigue’ and ‘concentration loss’. The results suggest that instructors’ perception and awareness of their learners’ listening processing and oral translation skills coupled with those of learners can provide rich information in developing listening and oral interpretation programs for translation students and trainers.

 Key words: oral interpretation, listening processing, knowledge, perception
Avaliação de conforto ambiental comparativa em edificações construídas em madeira laminada colada cruzada (Painéis CLT) e em sistemas construtivos tradicionais
Authors: França Marina Engel , Bogo Amilcar José
Published: February 2020

A conscientização ambiental do século XXI e as necessidades econômicas tem motivado a busca de tecnologias e sistemas construtivos sustentáveis para a arquitetura. Neste sentido, o uso de madeira passou a ser estimulado em países desenvolvidos, pois a madeira é um dos raros materiais de fonte renovável na construção civil. O painel CLT (Cross Laminated Timber) ou X-Lam ou ainda Madeira Laminada Colada Cruzada se enquadra nas exigências de menor impacto ambiental, inovação, facilidade de instalação, uniformidade e homogeneidade, e adequação a padrões internacionais. Entretanto essa nova tecnologia precisa ser validada em situações físicas e climáticas reais, inclusive comparando-a com outros sistemas tradicionais. O objetivo desse trabalho foi avaliar a qualidade de uma construção em CLT (Cross Laminated Timber) sob a abordagem do conforto ambiental. A edificação utilizada para esta avaliação é pré-fabricada em CLT ou X-lam, com dimensões de 20 x 10 m e construída no bairro Escola Agrícola em Blumenau, em área junto ao Instituto SENAI de Tecnologia.
Avaliação do contexto laboral e a qualidade de vida no trabalho de servidores públicos com deficiência
Authors: De Souza Juliana Werneck , Ferreira Mário César
Published: February 2020

O estudo buscou conhecer a percepção de servidores públicos com deficiência em relação a seu contexto laboral e a qualidade de vida no trabalho, sob a perspectiva da inclusão e da ergonomia da atividade. Foram realizadas 25 entrevistas semiestruturadas e os dados submetidos à análise léxica do discurso, com suporte do software IRaMuTeQ. Verificou-se a coexistência de representações de bem-estar e mal-estar, com certa predominância de representações de bem-estar. Observa-se bem-estar quando a organização do trabalho permite certo grau de autonomia, liberdade e flexibilidade, quando as relações socioprofissionais são harmoniosas, quando há espaço de fala e deliberação, quando existem oportunidades de crescimento profissional, aprendizagem e reconhecimento, equilíbrio entre vida pessoal e profissional e quando a chefia oferece suporte e promove a inclusão. O mal-estar se manifesta quando há falta de condições de trabalho, sobrecarga de tarefas, pressão por prazos, desconsideração às necessidades individuais, falta de espaço de diálogo. Em relação a aspectos relacionados à deficiência, os mais críticos foram a percepção de falta de oportunidades de ascensão pelos servidores cegos e pelos servidores com jornada especial reduzida. O estudo forneceu pistas para novas investigações e subsídios aos gestores para mudanças organizacionais no contexto pesquisado.
Impactos na saúde dos operadores em turnos de revezamento em uma empresa estatal
Authors: Ferreira Borges Anna Flávia , Macêdo Kátia Barbosa , Mesquita Simone Maria Moura
Published: February 2020

Este artigo apresenta parte dos resultados de um estudo empírico que teve por objetivo investigar os impactos do trabalho em regime de turnos de revezamento. Trata-se de uma pesquisa de caráter descritivo exploratório, embasado teórica e metodologicamente na abordagem da Psicodinâmica do Trabalho, realizado com um grupo de 12 trabalhadores de uma empresa estatal de energia elétrica ocupantes do cargo “operador de subestação e usinas hidrelétricas”, que desempenham atividades em turnos de revezamento. Para a coleta de dados da pesquisa, foram desenvolvidas três sessões de discussão coletiva e um encontro para validação da pesquisa. Os dados foram examinados por meio da análise Clínica do Trabalho. Com base nos resultados, foi possível constatar a respeito do trabalho em turnos, aliado à rotina rígida e burocrática dos trabalhadores estudados, a ocorrência de sofrimento por eles vivenciado, manifesto na dificuldade em conciliar trabalho e vida sociofamiliar; na sobrecarga doméstica; na dificuldade em se desligar do trabalho e nos riscos a que estão expostos pela profissão. Constatou-se, que o turno que mais impacta a saúde desses trabalhadores é o noturno, causando prejuízos evidenciados pelos sintomas de irritabilidade, desânimo, alterações de humor, dores de cabeça e cansaço, o que ocasiona em alguns estresse e depressão.
Práticas de exclusão social no Brasil de jovens em vulnerabilidade social e do segmento LGBTI
Authors: Rambaldi Mariana , Souza Marlos Coutinho Alves de , Lima Suzana Canez da Cruz , Freitas Malu
Published: February 2020

Neste trabalho procurou-se debater aspectos que envolvem impasses vivenciados pelos jovens e pelo segmento LGBTI no Brasil. O objetivo é discorrer sobre práticas de exclusão de jovens em situação de vulnerabilidade e do segmento LGBTI, com base especialmente na abordagem psicossociológica. Este trabalho utilizou pesquisa bibliográfica de caráter qualitativa. Parte-se do pressuposto de que estes indivíduos sofrem inúmeras formas de exclusão situando-se no imaginário da inutilidade, os ditos “inúteis” do campo social, aqueles que vivenciam nas cenas públicas as situações mais intensas de humilhação, depreciação e de desqualificação dos seus códigos sociais e culturais. O estudo apresenta, de forma sucinta, parâmetros da trajetória destes jovens que expressa a falta de acesso principalmente à educação a ao trabalho. Quanto ao segmento LGBTI, considera-se uma população vulnerável por diferirem em termos de comportamento e orientação sexual do padrão hegemônico fixado socialmente. Neste trabalho são apresentados dados sobre atos discriminatórios oriundos do preconceito e diversas formas de violência vividas pelos LGBTI. Sugere-se a ampliação do debate em espaços sociais da luta da população LGBTI e dos jovens em situação de vulnerabilidade como forma de visibilizar o sofrimento.
Programas de preparação para aposentadoria: um estudo na Ford Motor Company Brasil
Authors: Rocha Izabel Cristina , Peleias Ivam Ricardo , Franca Cristineide Leandro , Sampaio Joelson Oliveira , Gomes Jésus de Lisboa
Published: February 2020

Resumo
Esta pesquisa analisou se um programa de preparação para aposentadoria promoveu clareza de objetivos e mudança no comportamento de planejamento para a aposentadoria, em 137 empregados, da Ford Motor Brasil, sendo 69 participantes do programa e 68 que não participaram. Duas escalas foram respondidas online: perspectiva de tempo futuro relativa à aposentadoria e mudança em comportamento de planejamento para aposentadoria. Realizou-se análise fatorial exploratória, teste de medidas independentes de dois grupos e regressão linear multipla. O primeiro instrumento revelou uma estrutura unifatorial e o segundo quatro fatores. Não houve diferença significativa na comparação entre participantes e não-participantes do programa na mudança em comportamento de planejamento para aposentadoria. Constatou-se diferença significativa na clareza de objetivos para aposentadoria nos participantes do programa.
Palavras-chave: Preparação para aposentadoria; Perspectiva do tempo futuro; Envelhecimento; longevidade; Mudança de comportamento.
E-reputation Management of Hotel Indusrty
Authors: Anggani Mayang , Suherlan Herlan
Published: February 2020

The purpose of this study is to find out the e-reputation management of the hotel industry, as well as the social media channels used as the tools of hotel e-reputation building. This study used a qualitative approach by analyzing the in-depth interviews with hotel marketing communication practitioners of 15 hotel companies in Bandung City. The findings identified that e-reputation is considered a crucial factor in determining hotel performance due to the change of customers’ behaviors today and identified also three types of e-reputation management activities implemented by hotel companies, such as online activities, offline activities, and online/offline activities. The results of this study have implications for the hospitality industry, as a reference for formulating their marketing strategies.
Detection of Misconfigured Wi-Fi Tethering in Managed Networks
Authors: Choi Jaehyuk
Published: February 2020

Wi-Fi tethering using a mobile device (e.g., a smartphone or a tablet) as a hotspot for other devices has become a common practice. Despite the potential benefits of Wi-Fi tethering, the open source nature of mobile operating systems (e.g., Google Android) can be abused by a selfish device to manipulate channel-access parameters to gain an unfair advantage in throughput performance. This can cause serious performance problems within a well-planned Wi-Fi network due to an unauthorized selfish or misconfigured tethering device interfering with nearby well-planned access points (APs). In this paper, we demonstrate that the selfish behavior of a tethering node that adjusts the clear channel assessment (CCA) threshold has strong adverse effects in a multi-AP network, while providing the selfish node a high throughput gain. To mitigate this problem, we present a passive online detection scheme that identifies the network condition and detects selfish tethering nodes with high accuracy by exploiting the packet loss information of on-going transmissions. To the best of our knowledge, this is the first research to consider the problem of detecting a selfish tethering node in managed Wi-Fi networks.
On Bioquantum State Systems, The Study of Algebraic Ecology and Macrocellular Biology
Authors: Gotts Max
Published: February 2020

This dissertation is a rigorous study of ecology and macrocellular biology as a subfield of abstract algebra. We begin with the creation of an axiomatic paradigm, then move onto constructing a universal genetic code of biology. We use this to define increasingly complex algebraic structures (ecosystem, evolving populations, etc.). We prove a variety of theorems regarding to the members of the previous mathematical constructs, notably the following three: 1. There is one unique phenotypic representation of each organism. For example, if you subdivide any piece of genetic code into its phenotypic components, then two identical organisms have identical decomposed DNA 2. There are a finite number of indivisible phenotypic traits. 3. The three sophioid-definitions are equivalent: (a) dynamical evolutionary enlargement of the medial temporal lobe and frontal lobe, (b) reliance upon intelligence, (c) the existence of an intellectually- or socially-hierarchical society. Much has yet to be done on this work, but as a first draft, it stands as a jumping point for future exploits; I am working on an entirely revised second draft.
PENGARUH PENERAPAN PENDIDIKAN KARAKTER MELALUI MODEL PEMBELAJARAN STUDENT TEAM ACHIEVEMENT DIVISION TERHADAP HASIL BELAJAR PEMELIHARAAN MESIN KENDARAAN RINGAN SMK PANCASILA SURAKARTA
Authors: Farhan Sabiq , Ranto Ranto , Basori Basori
Published: February 2020

Tujuan penelitian adalah: 1) Untuk menemukan ada dan tidaknya perbedaaan pengaruh antara penerapan pendidikan karakter melalui model pembelajaran Student Teams Achievement Division (STAD) dengan konvensional terhadap hasil belajar mata pelajaran pemeliharaan mesin kendaraan ringan (PMKR). 2) Untuk menemukan hasil belajar dengan penerapan pendidikan karakter melalui model Student Teams Achievement Division (STAD) lebih tinggi dari konvensional konvensional pada mata pelajaran Pemeliharaan Mesin Kendaraan Ringan (PMKR). Penelitian ini merupakan penelitian kuantitatif quasi eksperiment. Teknik pengambilan sampel yang digunakan adalah simple random sampling. Populasi penelitian adalah kelas XI program keahlian Teknik Kendaraan Ringan dan sampel penelitian adalah siswa kelas XI-TKR 1 (23 siswa) dan XI-TKR 3 (22 siswa) Sekolah Menengah Kejuruan (SMK) Pancasila Surakarta. Teknik pengumpulan data yaitu menggunakan metode dokumentasi, observasi dan tes. Validitas instrumen penelitian yang dilakukan meliputi: uji validitas butir soal, reliabiitas soal, tingkat kesukaran dan daya beda soal. Uji prasyarat analisis meliputi uji normalitas menggunakan SPSS versi 21 Lilliefors (Shapiro-Wilk), uji homogenitas menggunakan SPSS versi 21 Levene-Statistic dan uji keseimbangan menggunakan SPSS versi 21 Independent Sample T Test. Uji hipotesis dengan mengunakan SPSS versi 21 Independent Sample T Test. Hasil penelitian ini yaitu: 1) ada perbedaan pengaruh yang signifikan antara penerapan pendidikan karakter melalui model Student Teams Achievement Divisions (STAD) dengan konvensional terhadap hasil belajar Pemeliharaan Mesin Kendaraan Ringan. 2) Hasil belajar dengan penerapan pendidikan karakter melalui model Student Teams Achievement Division (STAD) lebih tinggi dari konvensional.
Kata kunci: Penerapan Pendidikan Karakter, Student Teams Achievement Division (STAD), konvesional, dan Hasil belajar
PENGARUH PENGGUNAAN HYDROGEN ECO BOOSTER TIPE DRY CELL DENGAN VARIASI LARUTAN ELEKTROLIT TERHADAP TORSI DAN DAYA SEPEDA MOTOR 4 TAK BERBAHAN BAKAR PREMIUM
Authors: Kristanto Basti Wahyu , Bugis Husin , Rohman Ngatou
Published: February 2020

Tujuan penelitian ini adalah (1) Menyelidiki pengaruh penggunaan Hydrogen Eco Booster tipe Dry Cell terhadap torsi dan daya sepeda motor 4 tak berbahan bakar premium. (2) Menyelidiki pengaruh variasi larutan elektrolit pada penggunaan Hydrogen Eco Booster tipe Dry Cell terhadap torsi dan daya sepeda motor 4 tak berbahan bakar premium. Penelitian ini dilakukan di Laboratorium Otomotif Pendidikan Teknik Mesin Fakultas Keguruan dan Ilmu Pendidikan Universitas Sebelas Maret Surakarta dan di PT. Motocourse Technology (MOTOTECH). Penelitian ini merupakan penelitian kuantitatif deskriptif. Desain penelitian yang digunakan adalah desain eksperimen. Sampel penelitian dengan menggunakan sepeda motor Honda Supra X 125 tahun 2013. Alat eksperimen ini menggunakan Hydrogen Eco Booster tipe Dry Cell dengan menggunakan variasi larutan elektrolit air murni, KOH, dan NaOH. Metode pengumpulan data yang digunakan dalam penelitian ini adalah metode eksperimen. Hasil penelitian ini adalah: (1) Penggunaan Hydrogen Eco Booster Tipe Dry Cell berpengaruh terhadap torsi dan daya sepeda motor 4 tak berbahan bakar premium, yaitu diperoleh peningkatan torsi sebesar 0,11 N.m atau 1,16% dan peningkatan daya sebesar 0,10 HP atau 1,44% dibandingkan dengan pengujian kondisi mesin standar. (2) Penggunaan larutan KOH 12 gram/liter pada Hydrogen Eco Booster Tipe Dry Cell mempunyai tingkat kenaikan torsi dan daya yang paling tinggi dari variasi perbandingan larutan lainnya. Terjadi peningkatan torsi sebesar 0,08 N.m atau 0,84% dan peningkatan daya sebesar 0,14 HP atau 1,99 % dibandingkan torsi dan daya pada penggunaan Hydrogen Eco Booster tipe Dry Cell dengan air murni sebagai elektrolit tanpa katalis.
Kata kunci: Hydrogen Eco Booster tipe Dry Cell, elektrolisis air, larutan elektrolit, torsi, daya
Investigating the biomechanical function of the plate-type external fixator in the treatment of tibial fractures : a biomechanical study
Authors: Shi Di , Liu Kaiyuan , Zhang Haomeng , Wang Xinli , Li Guochen , Zheng Lianhe
Published: February 2020

Background

The design of an external fixator with the optimal biomechanical function and the lowest profile has been highly pursued, as fracture healing is dependent on the stability and durability of fixation, and a low profile is more desired by patients. The plate-type external fixator, a novel prototype of an external tibial fixation device, is a low profile construct. However, its biomechanical properties remain unclear. The objective of this study was to investigate the stiffness and strength of the plate-type external fixator and the unilateral external fixator. We hypothesized that the plate-type external fixator could provide higher stiffness while retaining sufficient strength.

Methods

Fifty-four cadaver tibias underwent a standardized midshaft osteotomy to create a fracture gap model to simulate a comminuted diaphyseal fracture. All specimens were randomly divided into three groups of eighteen specimens each and stabilized with either a unilateral external fixator or two configurations of the plate-type external fixator. Six specimens of each configuration were tested to determine fixation stiffness in axial compression, four-point bending, and torsion, respectively. Afterwards, dynamic loading until failure was performed in each loading mode to determine the construct strength and failure mode.

Results

The plate-type external fixator provided higher stiffness and strength than the traditional unilateral external fixator. The highest biomechanics were observed for the classical plate-type external fixator, closely followed by the extended plate-type external fixator.

Conclusions

The plate-type external fixator is stiffer and stronger than the traditional unilateral external fixator under axial compression, four-point bending and torsion loading conditions.
Baicalein neutralizes hypercholesterolemia-induced aggravation of oxidative injury in rats
Authors: Alsaad Abdulaziz MS , Almalki Mohammed S , Almutham Ibrahim , Alahmari Abdulwahab A , Alsulaiman Mohammed , Al-Rejaie Salim Saleh
Published: February 2020

Background: Hypercholesterolemia is a major risk factor for several cardiovascular and metabolic diseases as it triggers oxidative and pro-inflammatory cascades. Baicalein (BL) is a natural flavone with multiple therapeutic properties. The present study aimed to evaluate the potential protective effect of BL supplementation in hypercholesterolemic rats.
Methods: Rats were fed a high-cholesterol diet (HCD) for six weeks and then orally administered BL at two doses (25 and 50 mg/kg body weight/day) for four weeks. Serum lipids, liver enzymes, cardiac enzymes, renal markers, tumor necrosis factor-α, interleukin-6, interleukin-1β, interleukin-10, caspase-3, nitric oxide and prostaglandin-2 were measured. In renal, hepatic, and cardiac tissues, thiobarbituric acid-reactive substance, glutathione, superoxide dismutase, catalase, and glutathione peroxidase activities were measured.
Results: The altered levels of lipoproteins, aminotransferases, creatine kinases, and urea in hypercholesterolemic animals were significantly corrected by BL. Inflammatory and apoptotic biomarkers were also markedly attenuated in the HCD group following BL treatment. Hypercholesterolemia considerably induced the lipid peroxidation product, TBARS, and oxidative radicals in cardiac, hepatic, and renal tissues, which were attenuated by BL treatment, particularly, at the 50 mg/kg/day dose. BL enhanced the activities of superoxide dismutase, catalase, and glutathione peroxidase that were suppressed by HCD. Histological alterations induced by cholesterol overload in cardiac, hepatic, and renal tissues were ameliorated by BL supplementation.
Conclusions: Our results show that the co-administration of BL (25 and 50 mg/kg/day) in HCD rats improved all the altered parameters. Activation of cellular antioxidant enzymes and/or suppression of inflammatory cytokines may be involved in these prominent effects.
Leucine-rich α2-glycoprotein-1 upregulation in plasma and kidney of patients with lupus nephritis
Authors: Yang Yi , Luo Ran , Cheng Yichun , Liu Tingting , Dai Wei , Li Yueqiang , Ge Shuwang , Xu Gang
Published: February 2020

Background Increased leucine-rich α2-glycoprotein-1 (LRG1) has been observed in various inflammatory and autoimmune diseases. We aimed to explore the expression and role of LRG1 in lupus nephritis (LN). Methods Plasma LRG1 (pLRG1) was measured by enzyme-linked immunosorbent assay in 101 patients with renal biopsy-proven LN and 21 healthy controls (HC). Relationships between pLRG1 and clinical and pathological characteristics were analyzed. The expression of LRG1 in peripheral blood leukocytes and kidney was detected by flow cytometry, immunohistochemistry and immunofluorescence, respectively. Further cell experiments were focused on the role of LRG1. Results We found that LRG1 was expressed in plasma, some peripheral blood leukocytes, proximal tubule and several inflammatory cells. The levels of LRG1 in plasma, peripheral blood leukocytes and kidney were elevated in LN patients as compared to HC. Plasma expression levels of LRG1 correlated positively with renal function and renal disease activity, and reflect specific pathologic lesions in the kidneys of patients with LN. Interleukin-1β and interleukin-6, not tumor necrosis factor-α and interferon γ induced the LRG1 expression in human renal tubular epithelial cell line. Moreover, stimulation of recombinant human LRG1 could inhibit late apoptosis, promote proliferation and regulate expression of inflammatory factors and cytokines. Conclusions Plasma expression levels of LRG1 were associated with renal function, disease activity, and pathology in LN. It might also be involved in renal inflammation, proliferation and apoptosis of endothelial cells. LRG1 might be a potential prognosis novel predictor in LN patients.
S100A4 promotes colorectal carcinoma growth by enhancing aerobic glycolysis
Authors: Wu Guiyang , Wu Chongshan , Ye Fubo , Zhu Xiongwen , Chen Zaiping
Published: February 2020

Background Glucose metabolism transformation plays critical role in cancer cell malignancies maintenance. Aberrant cancer cell metabolism is considered to be the hallmark of cancer. S100A4 has been identified as an oncogene in a variety of cancers. However, its role in the cancer cell glucose reprogramming has been seldom reported. The aim of this study was to examine the role of S100A4 in aerobic glycolysis in colorectal cancer (CRC). Methods We investigated S100A4 expression in 224 cases of primary CRC and matched normal colonic tissue specimens, and explored the underlying mechanisms of altered S100A4 expression as well as the impact of this altered expression on CRC growth and glycolysis using in vitro and animal models of CRC. Results S100A4 was more highly expressed in CRC tissues than in the adjacent normal tissues (59.4% vs 17.4%, P <0.05). Higher S100A4 expression was associated with advanced node stage ( P =0.018) and larger tumor size ( P =0.035). A Cox proportional hazards model suggested that S100A4 expression was an independent prognostic factor for both OS (HR: 3.967, 95%CI: 1.919-8.200, P <0.001) and DFS (HR: 4.350, 95%CI: 2.264-8.358, P <0.001) in CRC after surgery. Experimentally, silencing S100A4 expression significantly decreased the growth and glycolysis rate of CRC both in vitro and in vivo . Mechanically, S100A4 could affect the hypoxia-inducible factor (HIF)-1α activity as demonstrated by the HIF-1α response element–luciferase activity in CRC cells. Conclusions These results disclose a novel role for S100A4 in reprogramming the metabolic process in CRC by affecting the HIF-1α activity and provide potential prognostic predictors for CRC.
Accuracy of rigid registration between amyloid / tau PET and MRI based on normalized mutual information
Authors: Iwao Yuma , Akamatsu Go , Wagatsuma Kei , Sakata Muneyuki , Ishii Kenji , Takahashi Miwako , Yamaya Taiga
Published: February 2020

Purpose Fusion images of positron emission tomography ( PET and magnetic resonance image MRI are effective to evaluate pathological changes using anatomical information. Registration of PET and MRI based on normalized mutual information (NMI) is widely used , where PET images change a lot depending on not only the choice of tracers but also disease progress ion , but the co registration accuracy has not been confirmed well yet. The aim of this study is to clarify the accuracy of NMI based registration between MRI and PET (amyloid PET and tau PET). Methods We obtained PET and MRI data from 69 participants (ages from 47 to 87 ) who underwent PET using one of the following four tracers 11 C PiB, 18 F Florbetapir, 11 C PBB3 or 18 F THK5351. T he ground truth (i .e .., a set of registered MRI PET images) was manually made by two experts. For each data set, 40 set of perturbed parameters were given to MR image s . Then each perturbed MR I was registered to the PET image using the statistical parametric mapping (SPM) tool. The differences between the given and the estimated shifts and rotates were calculated as registration errors. Results We found the registration errors were around 2 mm in the shift and around 1 deg in the rotation. These registration errors were independent of the amount of the perturbation given. Conclusion Although negative subjects of tau tracers showed higher error than other tracers, the registration error was less than PET spatial resolution, which supported a proof of the stability of the SPM.
Using human pluripotent stem cell differentiated endothelial cells to study the differential regulation in PAH
Authors: Qin Kezhou , Yang Jun
Published: February 2020

Aims Endothelial cells (ECs) have been applied in clinic to treat pulmonary arterial hypertension (PAH), a disease characterized by disordered pulmonary vasculature. However, lack of enough transplantable cells before the deterioration of patient condition is current limitation to apply cell therapy in cardiovascular diseases. So, we thought it necessary to continue to differentiate embryo stem cells (ESCs)/induced-pluripotent stem cells (iPSCs) into endothelial cells (ECs) and identify their characteristics. Methods and results Comparing previous reported methods of human pluripotent cell differentiation toward vascular cells/ Hemogenic Endothelial cells/ endothelial colony-forming cells, we established a highly efficient differentiation protocol to get cells that match phenotype of isolated ECs from health donors. This protocol, including two stages, early mesoderm endothelial progenitor stage and EC marker expression stage. In the first stage, Rock inhibitor Y27632 and DMSO plays an important role in inducing-APLNR + mesoderm and promotes EC differentiation potential; later on SB431542 and BMP4 drives cells toward EC lineage. Meanwhile, an improved protocol with chemically-defined medium (CDM) has similar differentiation efficiency,again demonstrating that a large number of clinically needed cells could be obtained with simple factors. ESC/iPSC-ECs, normal EPCs and IPAH-EPCs have the characteristics of early EPCs marked by CD133 and mesenchymal stem cells. Microarray analysis further revealed IPAH-derived EPCs features of rapid proliferation and weak immune regulation. At last, a model Zebrafish xenograft was utilized to assess the functionality of differentiated ESC/iPSC-ECs. ConclusionsWe established a highly efficient differentiation protocol to get ESC/iPSC-ECs with characteristics of phenotype and molecular matched with early-EPCs from health donors, and revealed the molecular pathogenesis in PAH.
Short-term observation of electric ablation with nanosecond pulsed electric field (nsPEF) on hepatic hilar area
Authors: Lu Jiahua , Qian Junjie , Zhang Shiyu , Chen Xinhua , Yin Shengyong , Zhou Lin , Zheng Shusen , Zhang Wu
Published: February 2020

Background: Treatment of liver malignancies located at the hepatic hilar area has long been recognized as a challenge for both surgeons and interventional radiologists. Traditional locoregional thermal ablative therapies like radiofrequency ablation (RFA) have natural deficiencies to achieve complete ablation. Nanosecond pulsed electric field (nsPEF) has emerged as a novel electric power based locoregional therapy. It has been reported to eﬀectively ablate liver malignancies while its effect on tumors located in hepatic hilar areas still lacks well-controlled follow-up studies. Methods: This pre-clinical study was conducted to evaluate the safety and feasibility of nsPEF ablation in the hepatic hilar area and to investigate its effect on liver vasculature systems. Two-needle electrodes of the nsPEF were placed around the hepatic hilar areas in the rabbit liver under ultrasonic guidance. During and after the procedure of nsPEF ablation, electrocardiographs (ECG) was used to monitor cardiovascular activities and ultrasonography was used to detect vascular changes. The blood samples and liver specimens were collected at pre-treatment and at 2 hours, 2 days, 7 days, 14 days and 28 days post-treatment. Results: Histopathological studies showed the targeted portal area was ablated accurately without perivascular sparing. The major structures of the large hepatic veins and bile ducts near hilar areas were preserved well. Follow-up biochemical tests showed a transient and mild impairment of liver function. The results of myocardial enzymes and routine blood test proved nsPEF won’t cause collateral damage on cardiac systems or increase potential infection risk. Ultrasonography and electrocardiographs found no massive hemorrhea and abnormal cardiac activities. Conclusion: Our results demonstrate that nsPEF is safe and feasible in the ablation of large animal models. During the treatment, nsPEF would not disturb vital organ functions or cause irreversible complications. Furthermore, it can ablate the hepatic hilar area without damaging large hepatic vasculatures, which could be a promising method for non-thermal tumor ablation.