bluuebunny/crossref_metadata_2025 huggingface dataset:
A Powerful Sisterhood: Black Women Scholars in Feminist HCI
Authors: Reece Shaniah , Adenuga Covenant , Ablorh Tierra , Rankin Yolanda A.
Published: January 2025

In this forum we explore different perspectives for how to apply intersectionality as a critical framework for design across multiple contexts. ---
Yolanda A. Rankin and Jakita O. Thomas, Editors
Being a First-Year Undergrad in Human-Centered Research
Authors: Anfang Lily , Flynn Maya , Gray Kaitlynn , Sandoval Ethan , Kirabo Lynn
Published: January 2025

The
Interactions
website (interactions.acm.org) hosts a stable of bloggers who share insights and observations on HCI, often challenging current practices. Each issue we'll publish selected posts from some of the leading and emerging voices in the field.
Prognostic Value of Cardiac MRI Late Gadolinium Enhancement Granularity in Participants with Ischemic Cardiomyopathy
Authors: Unger Alexandre , Garot Jérôme , Toupin Solenn , Duhamel Suzanne , Sanguineti Francesca , Hovasse Thomas , Champagne Stéphane , Unterseeh Thierry , Chevalier Bernard , Akodad Mariama , Neylon Antoinette , Hamzi Lounis , Gonçalves Trecy , Florence Jeremy , Gall Emmanuel , Martial Paul-Jun , Mirailles Raphael , Pfeffer Alexandre , Canuti Elena Sofia , Dillinger Jean Guillaume , Henry Patrick , Bondue Antoine , Bousson Valérie , Garot Philippe , Pezel Théo
Published: January 2025

A cardiac MRI model incorporating the ischemic late gadolinium enhancement (LGE) parameters of extent, transmurality, location, and midwall LGE significantly outperformed traditional risk factors in predicting all-cause mortality in participants with ischemic cardiomyopathy.
High Accuracy and Applicability Battery Aging Models for Electric Vehicle Applications
Authors: Yarimca Gulsah , Solberg Jensen Anders Christian , Cetkin Erdal
Published: January 2025

Batteries have gained significant attention due to their numerous advantages in applications such as electric vehicles. One of the factors limiting industry adoption is the aging of batteries. The characteristics of battery aging vary depending on many factors such as battery type, electrochemical reactions and operating conditions. Here we document the comparison of semi-empirical aging models (SEM), highlighting limitations and challenges. In addition, four SEMs are proposed. The usability and compatibility of these models are evaluated using experimental data from various sources including the Horizon 2020 Helios Project. The optimized parameters of each model are documented via linear regression and genetic algorithms. The results show that the genetic algorithm approach provides higher accuracy in comparison to the linear regression. The documented SEMs reveal better prediction performance than the literature of calendar obsolescence with SEM-3 and 7 performing particularly well in predicting capacity loss for the Helios dataset with low errors, i.e. 0.43 and 0.79 RMSE, respectively. The range of RMSE values for model predictions across all the datasets ranges from 0.196 to 3.903. This study aims to document the accuracy of SEMs both from the literature and proposed in the paper relative to battery ageing data from distinct sources.
Ventilatory long-term facilitation at rest increases the feedforward contribution to subsequent exercise ventilatory responses
Authors: Welch Joseph F. , Cretney Brighton R. , Mitchell Gordon S. , Balanos George M.
Published: January 2025

We demonstrate that by inducing ventilatory long-term facilitation (LTF) at rest, subsequent ventilatory responses to mild or moderate exercise are altered. When ventilatory LTF was induced via hypercapnic acute intermittent hypoxia, the feedforward contribution to exercise hyperpnea increased, accompanied by marginal increases in the overall system response and decreases in end-tidal Pco2. Thus, respiratory motor plasticity at rest can “spill over” to other physiological states, including mild or moderate steady-state exercise.
Unipotency of Matrix Group Generated by Two Matrices
Authors: Cheng Yanshuo , Yang Xinsong
Published: January 2025

In this paper, the problem of unipotency for the matrix group generated by two matrices is examined. By employing matrix logarithms as a tool, various combinatorial formulas for matrices were derived by selecting different primitive elements. Key conclusions were then reached through the organization and simplification of these formulas. It was ultimately demonstrated, based on these conclusions, that a matrix group G generated by two matrices, where the Jordan blocks do not exceed third order, must be unipotent if each primitive element of G is unipotent and has an order of six or less.
Effects of Different Dried Chlorella pyrenoidosa Preparations on Fatty Acid Profiles and Reproductive Outcomes in Daphnia carinata
Authors: Jin Jiaqi , Zhang Feng , Yang Tian , Jiang Yinan , Wei Wenzhi
Published: January 2025

Daphnia carinata is an important biological live feed in aquaculture. Conventionally, D. carinata is cultivated and fed with fresh Chlorella pyrenoidosa, which is inconvenient for storage and transportation. After undergoing vacuum freeze‐drying or spray‐drying, C. pyrenoidosa exhibits advantages such as reduced weight and easier storage and transport. This study investigated the effects of feeding freeze‐dried and spray‐dried Chlorella on the reproductive performance and fatty acid composition of D. carinata. The results indicated that there was no significant difference in reproductive performance between the two groups of D. carinata fed with freeze‐dried Chlorella and fresh Chlorella. However, a significant decline in reproductive performance was observed in the group fed with spray‐dried Chlorella. The contents of crude fat and unsaturated fatty acids in freeze‐dried Chlorella were significantly higher than in spray‐dried Chlorella. Additionally, D. carinata fed with freeze‐dried Chlorella exhibited significantly higher levels of unsaturated fatty acids (especially ALA and EPA) than those fed with spray‐dried Chlorella. In conclusion, freeze‐dried Chlorella can be used as an alternative to fresh Chlorella for cultivating D. carinata. Unsaturated fatty acids are a key factor influencing the reproductive performance of D. carinata.
Flavonoids of Tetrastigma hemsleyanum Diels et Gilg Against Acute Hepatic Injury by Blocking PI3K/AKT Signaling Pathway
Authors: Li Lingling , Zhan Lianghui , Wu Xiaojun , Jiang Xuechun , Pu Jinbao
Published: January 2025

Objective: This study aims to investigate the mechanism of Tetrastigma hemsleyanum Diels et Gilg flavonoids (THF) on acute hepatic injury (AHI).

Methods: First, high‐performance liquid chromatography (HPLC) fingerprints were established to obtain the main chemical components of THF. According to the network pharmacology databases, collect active targets of AHI and potential targets. Using interaction targets to construct a protein–protein interaction (PPI) network, followed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Finally, the affinity between the core targets and the main active ingredients was verified by molecular docking. Next, verified network pharmacology predictions with animal experiments. Mice were treated with THF (20, 40, and 80 mg/kg) for 7 days, and then built an acute liver injury model (lipopolysaccharide [LPS], 10 mg/kg). Detecting the liver biochemical indices, observe the liver pathological changes, and verify the key signaling pathway targets.

Results: HPLC showed that the main components of THF were quercetin and kaempferol. Seven active ingredients and 193 potential targets were screened, and 259 disease targets related to acute liver injury, quercetin, and kaempferol may be the main active ingredients in THF. PPI network analysis showed that tumor necrosis factor (TNF), interleukin‐6 (IL‐6), and tumor protein 53 (TP53) were potential targets of THF for the treatment of AHI. KEGG analysis showed that the phosphoinositide 3‐kinase (PI3K)/protein kinase B (AKT) signaling pathway might be one of the main pathways in the treatment of AHI. The molecular docking results showed that active compounds both have strong binding activity with potential targets in PPI. In vivo experiments showed that THF could reduce the fibrosis and inflammation of liver tissue etc. Meanwhile, it could downregulate the alanine aminotransferase (ALT), aspartate aminotransferase (AST), IL‐6, tumor necrosis factor alpha (TNF‐α), C‐reactive protein (CRP) levels, and the protein expressions of phosphorylated phosphoinositide 3‐kinase (p‐PI3K), phosphorylated protein kinase B (p‐AKT), and the ratio of BCL2‐associated X (BAX)/B‐cell lymphoma‐2 (BCL‐2) in the liver tissue of the mice with acute liver injury and upregulate the level of interleukin‐10 (IL‐10).

Conclusion: The treatment of acute liver injury with THF is characterized by multicomponents and multitargets, and its mechanism may be related to the alleviation of the inflammatory response, reduction of apoptosis, and regulation of the PI3K/AKT signaling pathway.
Socios y socias de las Big Four que han auditado empresas IPSA 2015-2022
Authors: González Valles Gabriela Alejandra
Published: January 2025

Desde el inicio de la profesión contable, las mujeres han tenido dificultades en la integración a esta y en ser consideradas profesionales cualificadas para enfrentar cualquier reto en los negocios, lo cual evoca los límites establecidos por los estereotipos de género que aun persisten en la sociedad. A pesar de la femilización que ocurrió en la carrera de Contador Público y Auditor en pleno siglo XXI, se ha identificado que los altos cargos de las empresas siguen estando fuera de alcance para las mujeres. Este ejercicio de investigación revisó las memorias anuales y estados financieros de las empresas del IPSA entre 2015-2022 con el objetivo de identificar si las mujeres están participando de estos escenarios profesionales o siguen siendo excluidas. Se encontró que, si bien hay pocas mujeres auditando dichas empresas, estas se ubican en la industria retail, segmentando su participación dentro del mercado de servicios profesionales de contabilidad y auditoría en Chile.
Maternidad. Cuestionamiento sobre las capacidades femeninas en la profesión contable
Authors: Herrera Becerra Paulina
Published: January 2025

Esta investigación se centra en describir los efectos de la maternidad en la carrera profesional de las mujeres Contadoras Públicas y Auditoras (CPA). El objetivo principal fue examinar cómo la maternidad impacta en las oportunidades profesionales dados los estereotipos y prejuicios asociados a la maternidad en el entorno laboral. Se realizar una revisión de literatura en las bases de datos para identificar el impacto sistematizado por la academia, evidenciando la importancia que tiene en la trayectoria profesional de las mujeres CPA. A pesar de las políticas de flexibilidad y apoyo a la maternidad implementadas por algunas empresas, la percepción general de que las madres están menos comprometidas con su trabajo persiste, lo que afecta negativamente sus oportunidades de ascenso y aumento salarial. Se identificaron estereotipos y prejuicios profundamente arraigados que asocian la maternidad con una disminución en la capacidad de las mujeres para asumir roles de liderazgo. Estos estereotipos influyen en la manera en que las empresas toman decisiones de contratación y promoción, perpetuando las desigualdades de género en el sector de la auditoría.
Supplementary Table S1 from Long-term Follow-up of Patients Having False-Positive Multitarget Stool DNA Tests after Negative Screening Colonoscopy: The LONG-HAUL Cohort Study
Authors: Cotter Thomas G. , Burger Kelli N. , Devens Mary E. , Simonson Julie A. , Lowrie Kari L. , Heigh Russell I. , Mahoney Douglas W. , Johnson David H. , Ahlquist David A. , Kisiel John B.
Published: January 2025

Supplementary Table S1
The spatial organization of cDC1 with CD8+ T cells is critical for the response to immune checkpoint inhibitors in melanoma patients
Authors: Gobbini Elisa , Hubert Margaux , Doffin Anne-Claire , Eberhardt Anais , Hermet Léo , Li Danlin , Duplouye Pierre , Ghamry-Barrin Sarah , Berthet Justine , Benboubker Valentin , Grimont Maxime , Sakref Candice , Perrot Jimmy , Tondeur Garance , Harou Olivier , Lopez Jonathan , Dubois Bertrand , Dalle Stephane , Caux Christophe , Caramel Julie , Valladeau-Guilemond Jenny
Published: January 2025

Dendritic cells (DCs) are promising targets for cancer immunotherapies because of their central role in the initiation and control of immune responses. The rare cDC1 population is of particular interest because of its remarkable ability to cross-present antigens (Ag) to CD8+ T cells, to promote Th1 cell polarization and NK cell activation and recruitment. However, the spatial organization and specific functions of cDC1s in response to immunotherapy remain to be clearly characterized in human tumors. Here, we implemented a multiplexed immunofluorescence analysis pipeline coupled with computational image analysis to determine the spatial organization of the cDC1 subset in a cohort of skin lesions from advanced melanoma patients treated with immune checkpoint inhibitors (ICI). For this, we performed a whole-slide image analysis of cDC1 infiltration and distribution as well as their spatial interactions with key immune partners such as CD8+ T cells and pDC according to the response of patients to ICI. We also analyzed LAMP3+-DC, which correspond to a mature subset of tumor-infiltrating DCs. Distance and cell network analyses demonstrated that cDC1s exhibited a scattered distribution compared to tumor-infiltrating pDCs and LAMP3+-DCs, which were preferentially organized in dense areas with high homotypic connections. Interestingly, the proximity and interactions between CD8+ T cells and cDC1s were positively associated with the response to ICI. In conclusion, our study unravels the complex spatial organization of cDC1s and their interactions with CD8+ T cells in melanoma patient lesions, shedding light on their pivotal role in shaping the response to ICI.
Trabectedin enhances the antitumor effects of IL-12 in triple-negative breast cancer
Authors: Schwarz Emily , Savardekar Himanshu , Zelinskas Sara , Mouse Abigail , Lapurga Gabriella , Lyberger Justin , Rivaldi Adithe , Ringwalt Emily M. , Miller Katherine E. , Yu Lianbo , Behbehani Gregory K. , Cripe Timothy P. , Carson William E.
Published: January 2025

Interleukin-12 (IL-12) is a potent NK cell–stimulating cytokine, but the presence of immunosuppressive myeloid cells such as myeloid-derived suppressor cells (MDSC) can inhibit IL 12-induced NK-cell cytotoxicity. Thus, we hypothesized that trabectedin, a myeloid cell–depleting agent, would improve the efficacy of IL-12 in triple-negative breast cancer (TNBC). In vitro treatment of healthy donor NK cells with trabectedin increased expression of the activation marker CD69 and mRNA expression of T BET (Tbx21), the cytotoxic ligands TRAIL (TNFSF10) and Fas ligand (FASLG) and the dendritic cell (DC)–recruiting chemokine lymphotactin (XCL1). The combination of IL-12 and trabectedin increased NK-cell cytotoxicity, activation and production of IFN-γ, TNF-α and granzyme B in the presence of human TNBC cells. Treatment of 4T1 and EMT6 tumor-bearing mice with IL-12 and trabectedin led to a significant reduction in tumor burden compared to single-agent controls, and the highest levels of plasma IFN-γ, intratumoral CD8+ T cells and conventional type 1 DC. MDSC and M2-like macrophages were significantly decreased with combination therapy. NK-cell depletion abrogated the effects of combination therapy, as did elimination of CD8+ T cells. NK-cell depletion led to lower levels of the NK cell–derived chemokine CCL5 and the DC-derived chemokine CXCL10, higher tumor burden, and decreased intratumoral CD8+ T cells. IL 12 and trabectedin also significantly enhanced the response of TNBC to anti-PD-L1 therapy. These data suggest that MDSC depletion augments the ability of IL-12-activated NK cells to drive the infiltration of DC and CD8+ T cells into TNBC for an antitumor effect.
Figure 6 from Claudin-4 Stabilizes the Genome via Nuclear and Cell-Cycle Remodeling to Support Ovarian Cancer Cell Survival
Authors: Villagomez Fabian R. , Lang Julie , Nunez-Avellaneda Daniel , Behbakht Kian , Dimmick Hannah L. , Webb Patricia G. , Nephew Kenneth P. , Neville Margaret , Woodruff Elizabeth R. , Bitler Benjamin G.
Published: January 2025

Impact of targeting claudin-4’s functional effects via CMP and FSK on ovarian cancer cell survival. Olaparib treatment was used as a reference (Supplementary Fig. S6D–S6F) to evaluate the effects of CMP and FSK on cell survival using the 7-day colony formation assay and crystal violet staining. Cells were treated as follows: two cycles of treatment (at days 0 and 3) for OVCAR8 and OVCAR3 cells and one treatment for OVCA429 (at day 0). A, Percentage of tumor cell survival during olaparib treatment vs. olaparib + FSK (5 µmol/L) and claudin-4 overexpression, and similar information during claudin-4 downregulation in OVCA429 cells (B) and OVCAR3 cells (C). D, Percentage of tumor cell survival during olaparib + FSK (5 µmol/L) vs. olaparib + FSK (5 µmol/L) + CMP (400 µmol/L) and claudin-4 overexpression, and similar information during claudin-4 downregulation in OVCA429 cells (E) and OVCAR3 cells (F), respectively (three independent experiments; two-way ANOVA; significance P < 0.05). Graphs show mean and SEM. KD, knockdown; Olap/olap, olaparib; Veh/veh, vehicle.
Figure 5 from Claudin-4 Stabilizes the Genome via Nuclear and Cell-Cycle Remodeling to Support Ovarian Cancer Cell Survival
Authors: Villagomez Fabian R. , Lang Julie , Nunez-Avellaneda Daniel , Behbakht Kian , Dimmick Hannah L. , Webb Patricia G. , Nephew Kenneth P. , Neville Margaret , Woodruff Elizabeth R. , Bitler Benjamin G.
Published: January 2025

Effect of combining olaparib, FSK, and CMP on LAT1 expression. Ovarian tumor cells were treated with a tripartite combination of olaparib (600 nmol/L), FSK (5 µmol/L), and CMP (400 µmol/L) for different time points. Subsequently, cell lysates were obtained to carry out immunoblotting for LAT1. A–C LAT1 protein expression at different time points in OVCAR8, OVCA429, and OVCAR3 cells, respectively. On the right are graphs showing the corresponding quantification of LAT1 from A–C relative to loading control. KD, knockdown; Veh/veh, vehicle.
Figure 3 from Claudin-4 Stabilizes the Genome via Nuclear and Cell-Cycle Remodeling to Support Ovarian Cancer Cell Survival
Authors: Villagomez Fabian R. , Lang Julie , Nunez-Avellaneda Daniel , Behbakht Kian , Dimmick Hannah L. , Webb Patricia G. , Nephew Kenneth P. , Neville Margaret , Woodruff Elizabeth R. , Bitler Benjamin G.
Published: January 2025

Remodeling of nuclear morphology and the nuclear lamina during claudin-4 disruption. Ovarian tumor cells were treated with CMP (400 µmol/L) for 48 hours, and then cells were stained to mark the nuclear lamina (using antibodies against lamin B1 and lamin A/C) and the nuclei (using DAPI). Subsequently, we performed a morphometric characterization. A, Top, confocal images showing (maximum projections) nuclei size of OVCAR8 as well as OVCA429 (B) and OVCAR3 cells (C). Bottom, corresponding quantification for (A–C; n = OVCAR8, 1711 cells; OVCA429, 2,630 cells; OVCAR3, 2,365 cells; two-tailed Mann–Whitney test, Kruskal–Wallis test with Dunn’s multiple comparisons; three independent experiments). D, Top, selected confocal images (maximum projections) showing nuclear lamina components corresponding to OVCAR8 cells overexpressing claudin-4 and claudin-4 downregulation in OVCA429 (E) and OVCAR3 cells (F). Bottom, corresponding quantification of nuclear accumulation of lamin B1 and lamin A/C (yellow arrowheads highlight comparison of lamin B1 during claudin-4 overexpression and downregulation) under different conditions (three independent experiments; Kruskal–Wallis test with Dunn’s multiple comparisons. (Significance, P < 0.05). Graphs show mean and SEM, scale bar, 5 µm. KD, knockdown; MFI, mean fluorescence intensity; Veh, vehicle.
Figure 1 from Claudin-4 Stabilizes the Genome via Nuclear and Cell-Cycle Remodeling to Support Ovarian Cancer Cell Survival
Authors: Villagomez Fabian R. , Lang Julie , Nunez-Avellaneda Daniel , Behbakht Kian , Dimmick Hannah L. , Webb Patricia G. , Nephew Kenneth P. , Neville Margaret , Woodruff Elizabeth R. , Bitler Benjamin G.
Published: January 2025

Cell-cycle progression during claudin-4 modulation. Ovarian tumor cells were cultured and stained for PI at 24, 48 (OVCAR8 and OVCA429 cells), and 96 hours (OVCAR3 cells). Subsequently, cell-cycle progression was evaluated via flow cytometry. A, Representative histograms of cell-cycle phases during claudin-4 overexpression; right, percentages of cells at each cell-cycle stage. Similarly, the effect of claudin-4 downregulation in OVCA429 (B) and OVCAR3 (C). D, Model illustrating that claudin-4 overexpression reduces the proportion of tumor cells in the S-phase of the cell cycle, whereas its downregulation results in an accumulation of cells in the G2–M phase and a decrease in the G0–G1 phase. (four independent experiments, three independent experiments for OVCAR3 at 96 hours; two-tailed unpaired t test; significance P < 0.05). Graphs show min to max (+ indicates mean). KD, knockdown; PI, propidium iodide.
Targeted Axillary Dissection Using Surgical Marker Navigation After Neoadjuvant Systemic Treatment in Breast Cancer Patients: A Single Center Experience
Authors: Egle Daniel , Brunner Cristine , Ritter Magdalena , Wieser Verena , Knoll Katharina , Amort Birgit , Soleiman Afshin , Fiegl Heidelinde , Marth Christian , Albertini Carmen , Bartsch Rupert
Published: January 2025

Background: In early-stage breast cancer with initially positive axillary lymph nodes, reliable assessment of the involvement of the axilla is important because of the prognostic importance of lymph-node metastases. After neoadjuvant chemotherapy (NACT) targeted axillary dissection (TAD) including sentinel lymph-node biopsy and primarily involved lymph nodes, is currently regarded as the standard of care. The target lymph node must be marked using a clip/marker and later localized using a reliable guidance technique to identify the node to avoid the indication of axillary lymph-node dissection.
Methods: The present study aimed to evaluate retrospective data collected from April 25th, 2022, until March 30th, 2023, on a consecutive series of patients, to determine the efficacy and safety of using the Sirius Pintuition GPSDetect™ surgical marker navigation system.
Results: This case series shows that identification of the target node with surgical marker navigation is feasible and safe with a 100% identification rate at surgery, in a population of patients with histologically verified axillary lymph-node involvement before NACT.
Conclusion: Magnetically guided localization systems may therefore be a valid alternative to ultrasound-guided wire placement. The data highlights the practicality of the magnetically guided approach, which potentially contributes to a reduction in treatment related morbidity by avoiding unnecessary axillary lymph node dissection.
Use of Endoflip – Impedance Planimetry System: For Which Indications?
Authors: Nagl Sandra , Ebigbo Alanna , Messmann Helmut
Published: January 2025

Background: The functional lumen imaging probe (EndoFLIP), which utilizes impedance planimetry, has emerged as a valuable tool for a more comprehensive evaluation of esophageal physiology and pathophysiology beyond traditional high-resolution manometry. Summary: EndoFLIP, including its variations EndoFLIP and EsoFLIP, measures intraluminal distensibility and compliance by assessing diameter and distension pressure using balloon catheters. Key Messages: This technology is applicable to various organs such as the esophagus, stomach, and anorectal region, and serves in both diagnostic and therapeutic contexts, especially in ambiguous clinical cases.
Persistierender Husten nach SARS-CoV2-Infektion: Bronchiale Obstruktion provozieren!
Authors: Keymel Stefanie
Published: January 2025

Background: Coronavirus disease 2019 (COVID-19) has a considerable impact on the global healthcare system. Individuals who have recovered from COVID often experience chronic respiratory symptoms that affect their daily lives. This study aimed to assess respiratory dynamics such as airway hyperresponsiveness (AHR) and bronchodilator response in post-COVID patients. Methods: This study included 282 adults with respiratory symptoms who underwent provocation tests. The demographic details, clinical symptoms and medical histories were recorded. Baseline spirometry, methacholine challenge tests (MCT) and post-bronchodilator spirometry were performed. Patients were divided into the following four groups: Group 1: non-COVID-19 and negative MCT; Group 2: post-COVID-19 and negative MCT; Group 3: non-COVID-19 and positive MCT; and Group 4: post-COVID-19 and positive MCT. Results: Most post-COVID-19 patients (43.7%) experienced AHR, and wheezing was more common. Patients in Group 4 exhibited increased intensities of dyspnoea, cough and wheezing with the lowest pulmonary function test (PFT) parameters at baseline. Moreover, significant decreases in PFT parameters after the MCT were observed in these patients. Although the prevalence of a low forced expiratory volume in 1 s to forced vital capacity ratio (<70%) was initially 2% in Group 4, it increased to 29% after MCT. No significant differences in allergic history or underlying diseases were observed between the groups.
A arqueologia de grupos caçadores-coletores na região de Piracicaba: estado da arte
Authors: Correa Letícia Cristina , Bradley Bruce , Okumura Mercedes , Parenti Fabio , Araujo Astolfo Gomes de Mello
Published: January 2025

The central portion of São Paulo State has proven to be an important location for identifying different types of artifacts associated with hunter-gatherer groups. Piracicaba city seems to be no different. Even with few registered archaeological sites, knowledge of the area can be built from analyzes of artifacts collected by local residents. We present results of unprecedented analyzes that allow us to propose cultural variability within what was called the Rioclarense Industry. This study also shows the importance of working with pieces without exact context, as a way of advancing knowledge in areas with few registered sites.
Inhibition of thalamic relay nuclei scales the aperiodic and alpha band oscillations associated with arousal during naturalistic stimulus viewing
Authors: Borah Ritu M. , Pathak Anagh , Banerjee Arpan
Published: January 2025

Existing psychological theories posit valence and arousal as two dimensions along which subjective emotions’ states are represented. The present study sought to determine whether the emotional ratings projected along the valence–arousal axis during naturalistic stimulus viewing are further mapped in the neurodynamical attributes observed from noninvasive electroencephalography (EEG) in humans and their potential biophysical causes. While several studies have explored the periodic features of EEG dynamics of emotion processing, very few studies have previously explored the aperiodic (1/f) components vis-à-vis emotion arousal. Recent signal processing developments have established that segregating EEG time series into aperiodic and periodic components provides fundamental insights underlying neural computations, specifically excitatory–inhibitory balance. In this study, we identified that there is a significant increase in exponent and offset of aperiodic background during arousal. In contrast, there were no discernible variations between the aperiodic components during the differential valence scenarios. Reduction in periodic alpha power was observed with high arousal in line with previous studies. Finally, implementation of a biophysically realistic corticothalamic model of neural field activity allowed us to mechanistically explain that both the empirical observations of heightened arousal represented as higher slope of aperiodic background and decrease in power of the periodic alpha oscillations emerge from an increased inhibitory influence to relay nuclei of the thalamus.
Modelling low-dimensional interacting brain networks reveals organising principle in human cognition
Authors: Perl Yonatan Sanz , Geli Sebastian , Pérez-Ordoyo Eider , Zonca Lou , Idesis Sebastian , Vohryzek Jakub , Jirsa Viktor K. , Kringelbach Morten L. , Tagliazucchi Enzo , Deco Gustavo
Published: January 2025

The discovery of resting-state networks shifted the focus from the role of local regions in cognitive tasks to the ongoing spontaneous dynamics in global networks. Recently, efforts have been invested to reduce the complexity of brain activity recordings through the application of nonlinear dimensionality reduction algorithms. Here, we investigate how the interaction between these networks emerges as an organising principle in human cognition. We combine deep variational autoencoders with computational modelling to construct a dynamical model of brain networks fitted to the whole-brain dynamics measured with functional magnetic resonance imaging (fMRI). Crucially, this allows us to infer the interaction between these networks in resting state and seven different cognitive tasks by determining the effective functional connectivity between networks. We found a high flexible reconfiguration of task-driven network interaction patterns and we demonstrate that it can be used to classify different cognitive tasks. Importantly, compared with using all the nodes in a parcellation, we obtain better results by modelling the dynamics of interacting networks in both model and classification performance. These findings show the key causal role of manifolds as a fundamental organising principle of brain function, providing evidence that interacting networks are the computational engines’ brain during cognitive tasks.
The Danish-Halle Mission from the Perspective of Embodiment: Communication, Ritual, and the Body in Interreligious Contact
Authors: Lind Erki
Published: January 2025

This article studies the role of the body in interreligious contact by looking at the eighteenth-century Danish-Halle mission in South India. The missionaries’ theological arguments were mostly well received by Tamil Hindus, but the bodily lived religion and everyday experience determined the relationship with Christians. It was not only two different theologies that interacted, but two different conceptions of man. The missionaries used verbal communication and sought common ground in concepts, but the article argues that the body also participates in the communication process. The article argues first that the body is a center of relations, and that these relations are created in ritual. Separate rituals not only hold persons in separate networks of relations but create separate worldviews that lay the basis for separate concepts. Second, the body connects the doctrine with ritual and behavior, and the way the body experiences reality forms the basis for lived religion.
Tibetan Remediations: Wax Doubles of Khenpo Jigme Phuntsok
Authors: Brox Trine
Published: January 2025

This article contributes to the study of material religion a discussion on the notion of remediation, by exploring the affordances of the waxwork as a new medium in the Tibetan Buddhist field. It shows how Tibetan waxworks are remediations in two senses of the word. Like the new media forms explored in other studies, they reference older media, blending the popular hyperreal waxwork that we know from Madame Tussauds and the well-established religious mediums of the statue and photo icon. But they can also remediate in the sense of restoration, evoking an experience of bodily copresence with the deceased (or otherwise absent) that can exceed the propinquity afforded by other media used as proxies. Drawing on observations of and interviews with people interacting with waxwork doubles of the Tibetan Buddhist authority Khenpo Jigme Phuntsok (1933–2004), I explore how such remediations can have limited but also unexpected potency and authority.
The Impact of School Support on College Students’ Willingness to Start Their Own Businesses: a Regulated Mediating Effect in Shaanxi
Authors: Yuan Zhaoyang , Chen Wei , Yuan Xiaofei
Published: January 2025

To explore the influence mechanism of school support on college students ‘entrepreneurial willingness, this study conducted a questionnaire survey on 241 college students in three universities in Shaanxi, and the results found that college students’ entrepreneurial willingness, entrepreneurial self-efficacy plays a positive intermediary role; gender not only plays a direct role between the school support and college students ‘entrepreneurial willingness, but also regulates the indirect relationship between school support and college students’ entrepreneurial self-efficacy. These studies found theoretical and practical significance: on the one hand, increasing school support can significantly enhance the entrepreneurial willingness of college students by enhancing the self-efficacy of entrepreneurship; on the other hand, female college students seem to be less sensitive to male college students ‘entrepreneurship support, indicating that the existing school support measures may not take into account the gender differences of students, and need to reflect to develop entrepreneurial support measures suitable for students’ gender characteristics.
Plurilateral Agreements, Multilateralism and Economic Development
Authors: Hoekman Bernard M. , Mavroidis Petros C.
Published: January 2025

Plurilateral agreements among sub-sets of economies have a long history within the multilateral trading system. Plurilaterals may appear superficially less attractive than a set of non-discriminatory multilateral rules that apply to all WTO members but may, both in theory and in practice, be better suited to accommodate diversity across countries in the desire and ability to regulate certain aspects of economic activity. As long as such differences between countries do not lead to discrimination or encroachment on other countries’ rights under WTO rules, it is potentially beneficial for the trading system to permit groups of countries to pursue regulatory cooperation, even if other countries do not wish to follow suit. The alternatives to greater accommodation of plurilateral cooperation in the WTO are more preferential (discriminatory) trade agreements and club-based initiatives outside the WTO. Both options are arguably worse for non-participating developing countries than incorporating open, transparent plurilateral agreements into the WTO. Opponents of plurilateral initiatives operating under WTO auspices run the risk of inducing further erosion of the multilateral trading system.
Integrative taxonomy of introduced Haplosclerida and four new species from Hawaiʻi
Authors: VICENTE JAN , RUTKOWSKI EMILY , LAVROV DENNIS V. , MARTINEAU GABRIELLE , TIMMERS MOLLY , TOONEN ROBERT J.
Published: January 2025

Haplosclerid sponges (Porifera: Demospongiae: Heteroscleromorpha), and particularly the family Chalinidae, are notoriously difficult to identify through taxonomic methods alone. Here we use an integrative approach to confirm the identification and report both polymorphic characters and different morphotypes exhibited from a recruitment stage that complicate identification of introduced haplosclerid species Haliclona (Soestella) caerulea and Gelliodes conulosa sp. nov. in Hawaiʻi. Using these same methods, we also describe three new species Haliclona (Gellius) pahua sp. nov., Haliclona (Reniera) kahoe sp. nov., Haliclona (Rhizoniera) loe sp. nov. from our collections in Kāne‘ohe Bay. Using a combination of mitochondrial and ribosomal RNA sequences, we compile a phylogeny that is consistent with previous molecular work but is at odds with the morphological characters used to classify species belonging to Chalinidae and Niphatidae families within Haplosclerida. Although shared morphological traits were distributed across taxa throughout the tree, both mitochondrial and ribosomal RNA sequences were diagnostic, with an average of at least 3 % sequence divergence among species and their closest relative. This study highlights both the use of standardized Autonomous Reef Monitoring Structures (ARMS) to access the hidden diversity of haplosclerid sponges, and the potential for competition between these introduced and newly described and potentially endemic species.
Redescriptions of Homoplectra japonica (Banks 1906) and H. albomarginata (Ulmer 1907) (Trichoptera, Hydropsychidae), with descriptions of five new similar species from Japan
Authors: NOZAKI TAKAO
Published: January 2025

The two known Japanese species of the genus Homoplectra, H. japonica (Banks 1906) and H. albomarginata (Ulmer 1907), are redescribed, and five new similar species are described, H. flagelliformis sp. nov., H. shikoku sp. nov., H. bicornis sp. nov., H. kimi sp. nov., and H. inazui sp. nov. A lectotype is selected for Arctopsyche japonica Banks 1906 for nomenclatural stability. The adults of these species have distinct yellow and black markings on their wings, which are unique among known congeners. A diagnostic species group, the Homoplectra japonica Species Group, is recognized based on wing markings and venation and the shape of the male phallic apparatus. Descriptions are provided for males and females of all species, and the immature stages of H. japonica and H. albomarginata. Larvae of H. japonica and H. albomarginata were found in seeps and small flows in mountain areas.
Contributions to the genus Bolbochromus Boucomont, 1909 (Coleoptera: Geotrupidae: Bolboceratinae) from China, with the description of a new species
Authors: GAO HAO , GESHEV GEORGI A.
Published: January 2025

A new species of the genus Bolbochromus Boucomont, 1909, Bolbochromus sunfengyii Gao & Yang, new species, is described from Yunnan, China. The female of B. nomurai Li & Krikken, 2013 is described for the first time. Bolbochromus sinensis Krikken & Li, 2013 is newly recorded from Jiangxi and Zhejiang Provinces. Elytral color pattern variations of the aforementioned species are also provided.
The Labor of Distinction: Butlers, Service Work, and the Production of Elite Lifestyles
Authors: Boyle Bryan , Vandebroeck Dieter
Published: January 2025

Elites appropriate labor that produces and reproduces distinct lifestyles. This article shows how the practice of this type of labor—what we term the “labor of distinction”—consists of four core dimensions: (1) curatorship, in the management of employers’ class symbols; (2) menialism, in freeing employers from “vulgar” practices; (3) Veblenian embodiment, in signaling employers’ status through bodily display; and (4) non-personship, in procuring social distance between laborer and employer, typically through concealment. Drawing from an “enactive” ethnography of the butler profession, where the lead author trained and worked as a butler in the UK, we illustrate the operation of all four of these dimensions and how they complement one another. By situating the butler in relation to other labor roles and occupations, we theorize a division of labor to outline how types of workers are differentially poised to serve elite distinction, and how elites with varying levels of purchasing power across geographic and historical contexts may incorporate labor in their distinction strategies. Our conceptualization comes at a time when the capacity for elites to employ this labor is growing and is, we argue, important to further understand elite symbolic power.
Economic Evidence in Occupational Therapy: A Rapid Review
Authors: Freeman Andrew R. , Larivière Nadine , Baillet Judith , Beauchemin Rachel , Lavoie-Trudeau Étienne , Martel Myriam , St-François Mégan
Published: January 2025

Background. Given the necessity to demonstrate that occupational therapy services are a good use of resources, understanding the state of economic evidence is essential. Purpose. This article presents a rapid review of this evidence. Method. Relevant articles were identified using SCOPUS. Eligible studies included economic analyses of interventions that included occupational therapy and were published in English or French after 1999. The findings were synthesized and then appraised using the Quality of Health Economic Studies (QHES) template. Results. The 135 studies identified were conducted in 23 countries and most commonly: with adults/older adults; in home, inpatient, outpatient, and rehabilitation centre settings; with individuals with cerebrovascular accident and orthopaedic conditions. The specific occupational therapy role was specified in 60% of the studies. Approximately 50% of the investigations used a randomized controlled trial and a cost effectiveness analysis, and 40% used a societal economic perspective. The average QHES score was 74.4/100 (reasonable quality). Implications. This review has revealed areas of relative strength, some important gaps, and potential directions for future action. Economic evidence that specifically identifies the occupational therapy contribution must continue to be gathered. The profession should consider the strategic alignment of its economic research (e.g., home care) to maximize its impact.
Investigation of IN625, IN939 and IN738 superalloy filler powders utilization in the direct metal deposition repair practice of IN738 gas turbine blade
Authors: Amirjan Mostafa , Khodabandeh Masoumeh
Published: January 2025

In the present work, three different superalloy filler powders IN625, IN939 and IN738 subjected to direct metal deposition on IN738 substrate. The repair process was done on lower part of a blade airfoil. Then, the cross-section of repaired zones was characterised using optical microscopy, scanning electron microscopy and phase analysis. Also, the hardness of repaired zone, substrate and heat-affected zone were investigated. The results showed, in a certain processing parameter, the crack-free precipitates of IN625 and IN738 was obtained. For IN939, a macro-crack along the build direction was observed. Due to the difference in the growth direction of the dendrites on both sides of the macro-crack, a high-angle grain boundary (HAGB) with a large misorientation angle >15° was formed, resulting in increased cracking susceptibility and development of a macro-crack. No γ’ phase was observed for as-deposited IN738 and IN939 due to cooling rate faster than 105(K.s−1).
Streamlining Online Astronomy Education: Integrating ChatGPT and Stellarium Planetarium Software to Serve as a Virtual Teaching Assistant
Authors: Li Linghong , Patton Wayne F.
Published: January 2025

The evolving landscape of higher education demands integrating advanced technologies to foster engaging and inclusive learning environments. This paper examines the practical integration of Stellarium, a virtual planetarium software, and ChatGPT, an AI conversational agent, in an asynchronous online undergraduate astronomy course. Stellarium enables students to explore celestial phenomena in an interactive virtual setting, enhancing conceptual understanding. ChatGPT supports instructor oversight by facilitating interactive discussions, answering student queries, and providing personalized tutoring, thereby promoting active engagement. By showcasing the implementation process and its impact on student learning, this study demonstrates how merging innovative pedagogies with cutting-edge tools can enhance online astronomy education and offers insights for broader applications across disciplines.
Autism Screening in High-Likelihood Children in a Community Early Intervention Setting: A Hybrid Effectiveness-Implementation Study
Authors: Perez Liz Georgina , Thao Diana , Reeb Katelyn , Goy Ilene , McCurdy Erin , Yudell Michael , Robins Diana L.
Published: January 2025

Identification of likelihood for autism in the early intervention (EI) system facilitates referrals to diagnostic assessments and targets autism-specific needs. However, performance of autism screeners in high-likelihood preschool children and barriers to implementation need to be further studied. The current effectiveness-implementation hybrid type 1 study examined the impact of administering the Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-CHAT-R/F) in a sample of preschool children during the EI intake phone call. Data from 2,661 educational records showed that 42.8% of them received the M-CHAT-R. Only 14.0% of the screen-positive children completing the process to determine eligibility for EI services were referred for an autism-specific evaluation. Most of these (94.8%), regardless of screener status, received an autism diagnosis, suggesting that referrals are based on clinical judgment. Training and incorporation to current protocols within agencies are necessary to introduce a screening tool and support implementation fidelity and effective autism detection.
The influence of daily traumas among Turkish Cypriot and Greek Cypriot journalists residing in a divided and conflicted environment
Authors: Yontucu Huri , Ersoy Metin
Published: January 2025

The world has faced a series of challenges, starting with the COVID-19 crisis and followed by economic downturns. Among these significant issues, daily occurrences of crimes, rape and natural disasters continue to unfold. These crises have mainly influenced journalists due to the high nature of their profession. This study investigated the psychological influence of daily crises on media workers, their coping strategies, their distress tolerance and how these variables influence one another. It also aimed to understand whether there is any difference between the two communities working in northern and southern Cyprus, a divided European country. One hundred and six journalists participated in the study, with 69 Turkish Cypriots and 37 Greek Cypriots. Results showed that both community journalists face traumatic emotions, have a low level of distress tolerance and utilise some adaptive coping strategies. Based on the psychological conditions that influence media professionals’ approaches to news coverage in fostering or hindering peacebuilding efforts, it is vital to examine the influence of daily crises in divided and conflicted societies.
Bio-lubricants as viable replacements for mineral oils in automotive engines: A review
Authors: Pendbhaje Gaurav , Ali Mohammed , Bajaj Dipak
Published: January 2025

This review paper explores the potential of bio-lubricants as sustainable alternatives to conventional mineral oils for the lubrication of automotive engines. Bio-lubricants, which are derived from renewable sources such as vegetable oils, provide substantial environmental advantages, such as reduced toxicity and biodegradability. The review summarizes the results of recent research, emphasizing the superior lubricity, oxidative stability, and wear resistance of bio-lubricants, particularly those that have been formulated with additives to improve performance. The chemical structure and fatty acid composition of vegetable oils, including soybean, palm, and cottonseed oils, are the subject of discussion, as they have a significant impact on their lubrication properties. The efficacy of advanced modeling techniques, such as genetic algorithm (GA) and artificial neural networks (ANN), in the prediction and optimization of bio-lubricant formulations is assessed. Despite their promising qualities, bio-lubricants encounter obstacles such as fluctuations in raw material quality and increased production costs. The review underscores the necessity of ongoing research and development to confront these obstacles, with an emphasis on enhancing performance consistency and cost-effectiveness. It is argued that the transition to bio-lubricants is a crucial step in the pursuit of sustainable automotive lubrication, as it reduces dependence on non-renewable resources and mitigates environmental damage. Future research directions and recommendations are suggested to further improve the applicability and adoption of bio-lubricants in the automotive industry.