bluuebunny/crossref_metadata_2025 huggingface dataset:
Model Data Mining Time Series Untuk Prediksi Profitabilitas Perusahaan
Authors: Junaidi Muksan , Widyassari Adhika Pramita
Published: April 2020

Profitabilitas merupakan rasio keuangan yang memperlihatkan kemampuan operasional perusahaan untuk menghasilkan laba operasi melalui modal sendiri. Untuk melihat kondisi kemampuan operasional perusahaan pada masa mendatang, bisa dilakukan dengan memprediksi nilai rasio tersebut. Teknik dalam menangani masalah prediksi ini adalah menggunakan model data mining. Penelitian ini bertujuan mengembangkan aplikasi prediksi profitabilitas keuangan perusahaan melalui model data mining neuro-fuzzy ANFIS dengan data time series. Data penelitian adalah data sekunder bersifat kuantitatif dari wibe site www.idx.co.id. Populasi data dari perusahaan emiten LQ45 di Bursa Efek  Indonesia(BEI) tahun 2011-2016 berjumlah 45 perusahaan. Pemrosesan awal menghitung nilai rasio keuangan perusahaan yang akan dipakai sebagai data input pada model ANFIS. Simulasi dan evaluasi model menggunakan aplikasi GUI program Matlab. Perbandingan antara perhitungan rasio profitabilitas tahun yang di prediksi dengan nilai dari model ANFIS. Hasil akhir menunjukkan bahwa nilai model ANFIS sangat optimal, efisien, konsisten dan paling mendekati rata-rata nilai rasio tahun yang di prediksi sebesar 9.95% pada fungsi keanggotaan Segitiga. Sedang hasil prediksi tiga fungsi keanggotaan lainnya Trapesium, G-bell dan Gauss kurang optimal.
SELEKSI FITUR WARNA CITRA DIGITAL BIJI KOPI MENGGUNAKAN METODE PRINCIPAL COMPONENT ANALYSIS
Authors: Nugraha Danang Aditya , Wiguna Anggri Sartika
Published: April 2020

Proses klasifikasi citra digital dilakukan terhadap data fitur yang menggambarkan ciri suatu citra. Dalam penelitian sebelumnya mengenai klasifikasi biji kopi untuk menentukan tingkat roasting, digunakan fitur warna RGB dan metode klasifikasi Jaringan Syaraf Tiruan dengan algoritma Back Propagation. Namun dalam penelitian tersebut didapatkan hasil klasifikasi yang kurang memuaskan akibat dari fitur yang digunakan kurang dapat memisahkan ciri dari setiap tingkat roasting biji kopi. Pada penelitian ini dilakukan penambahan fitur warna yang digunakan melalui penggunaan representasi warna RGB dan HSI, yang kemudian dihitung nilai mean, median, standar deviasi, skewness, kurtosis, dan energy pada setiap komponen warna. Dengan demikian terdapat 33 data fitur citra biji kopi. Dengan jumlah fitur yang semakin banyak, menimbulkan masalah baru dimana tidak setiap fitur mempunyai kontribusi yang signifikan dalam proses klasifikasi, sehingga diperlukan proses seleksi fitur untuk mendapatkan fitur dengan kontribusi maksimal. Pada penelitian ini metode Principal Component Analysis diujikan sebagai metode untuk seleksi fitur. Uji coba dilakukan terhadap 240 data citra digital biji kopi, dimana terdapat 120 citra biji kopi Arabika dan 120 citra biji kopi Robusta. Setiap jenis citra biji kopi tersebut terbagi menjadi tingkat roasting mentah, light roasting, medium roasting, dan dark roasting. Hasil penelitian ini didapatkan bahwa rata-rata proses training pada data fitur setelah dilakukan proses seleksi fitur mengalami peningkatan  dibandingkan tanpa seleksi fitur. Hal ini terlihat dari 5 kali proses training dengan seleksi fitur didapatkan nilai akurasi terbaik hingga 90,8%, sedangkan tanpa seleksi fitur didapatkan akurasi terbaik adalah 89,6%.
Comparative study of time taken for skin closure, infection rate and postoperative pain in skin closure with sutures and staplers in open inguinal hernioplasty
Authors: Rajasenthil V  , Sriraman K B  , Kaliyappa C
Published: April 2020

Wound healing is a complex and dynamic process and is influenced by surgical technique. Optimal wound healing, with a minimal scar that compromises neither appearance nor function, is the desired result. This process is affected by both local and systemic factors. Many local conditions are readily controlled at the time of wound closure, and several fundamental principles of surgical wound closure exist that should be adhered to in the management. Skin is usually closed with sutures then later with skin staplers.Skin staplers are quick and easy to use, but an assistant is usually required to hold the skin edges accurately with forceps or skin hooks.Stapler's closure also causes considerably less damage to wound defenses than closure with least reactive non-absorbable suture. Standard suturing causes significantly more necrosis than stapling in myocutaneous flaps. We did this study to compare the time required for the closure of skin, infection rate, pain at the operated site with sutures and staplers in open inguinal hernia repair. 80 patients who were posted for elective open inguinal hernia surgery at Sri Ramachandra Medical College & Research Institute, porur, Chennai was included in this study. Time taken for closure of skin, infection rate and the pain was less in patients with stapler closure than with skin sutures
Enhancement of solubility and bioavailability of modafinil using nanoparticles
Authors: Balachandar K  , Subramanian S
Published: April 2020

The aim of the present work is to develop polymeric nanoparticles using Modafinil to improve its solubility, thereby increasing its bioavailability. Ionic-Gelation method has been employed for the preparation of nanoparticles using chitosan, a natural polymer, and TPP, a cross-linking agent. In this method, the drug is mixed with a polymer and maintained at a pH between 4.5 - 5.5, and the solution of TPP is added to the polymer-drug mixture under magnetic stirring. The size of nanoparticles prepared by this method usually ranges from      1-1000 nm. The reduction in the size of particles directly enhances the solubility of drug that increases its bioavailability. Nine formulations (F1-F9) of nanoparticles were optimized by varying the concentrations of chitosan and TPP. Prepared nanoparticles were evaluated for size, zeta potential, PDI, and drug content. Formulation F9 with 0.25% of chitosan & 0.5% of TPP concentration has been chosen as best formulation and lyophilized to obtain solid nanoparticles. The obtained nanoparticles loaded with modafinil are used for the preparation of tablets, and the in-vitro dissolution characteristics are compared with the marketed tablet of modafinil. in-vitrocharacteristics of tablets with modafinil loaded polymeric nanoparticles showed improved solubility than a marketed tablet.
Isolation, Identification and Characterization of Ximenynic Acid with Anti-Aging Activity from Santalum Album
Authors: Shivatare Rakesh S , Musale Ramesh , Lohakare Priya , Patil Dipika , Choudhary Durga , Ganu Gayatri , Nagore Dheeraj H , Kewatkar Shailesh M
Published: April 2020

Medicinal plants and its products have been used as a remedial agent in most irising countries for treating diseases. Furthermore, an increasing reliance on the use of medicinal plants in industrialized societies has been traced for the extraction and development of several drugs and chemotherapeutics from these herbal plants. Novel acetylenic fatty acids named Ximenynic acid (XMA) were successfully isolated from the seeds of Santalum album L by N-Hexane extraction. Ximenynic acid (or Santalbic acid) is one of the few acetylenic fatty acids occurring at higher levels in plant seed oils. Ximenynic acid predominantly exists in the seed oil of Santalaceae, Olacaceae, and Opiliaceae families. The structure of XMA was characterized by UV-visible spectroscopy, Infrared Spectrum(IR), NMR Spectroscopy, Differential scanning calorimetry (DSC), Thermal Gravimetric Analysis (TGA), X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy(FT-IR), LCMS spectral analysis. The antiaging activities were assessed by anti-collagenase enzyme assay. Structural analysis revealed that XMA was a crystalline material with a melting point of 38.25°C and an average molecular weight of 278 kDa.Which is composed of carboxylic acid, butylene acid, methylene, allylic in their structure. The antiaging assay showed that XMA exhibited significant collagenase inhibition activity as compared with Catechin. These findings suggested that the acetylenic fatty acids XMA could be served as a novel antiaging in Pharmaceutical as well as the cosmetic industry.
Vitamin D Adequacy & Improvements In Children with Developmental Coordination Disorder
Authors: U Ganapathy Sankar , R Monisha , Vallaba Doss Christopher Amalraj , R M Palanivel
Published: April 2020

Children and adults with Developmental coordination disorder are more prevalent in vitamin D deficiency. Vitamin D – Sunshine vitamin is deficient because of poor physical activity in the green land. Vitamin D plays a vital role in muscle coordination &neural activation. It also enhances immunity, boosts metabolism and protects against secondary infections. When research articles related to vitamin D level supplementation are reviewed, it has been identified that the focus of the research was on risk-benefits. Researches were focused towards general interpretations of the test result. Vitamin D requirement for normal population is 20 ng/mL to 30 ng/mL (75 nmol/L). wide literature search has proved that a person with cancer, autoimmune disease, Cardiovascular disorders and the person with any developmental disability and DCD must consider 40 ng/mL (100 nmol/L) as a minimum level to avoid co-morbidities. Children and adults with DCD need adequate physical activity in green land, which facilitates sunlight exposure and there should be a compulsory oral supplementation. This study examines vitamin D requirements for the musculoskeletal system and improvements in children with DCD and it insists on the need for vitamin D for enhancing performance in ADL .
Effectiveness of dysphagia exercises on swallowing ability among patients with Cerebrovascular Accidents
Authors: Bhuvaneshwari G  , Somiya C
Published: April 2020

Cerebrovascular  accident  (CVA)  is one of the foremost reasons leading to mortality and morbidity throughout the world. It is the third biggest killer in India after a heart attack and cancer.  It is like a chronic health condition which negatively impacts on quality of life. Dysphagia is one of the most successive side effects in patients with a stroke which is a loss of motion of throat muscles. This condition can disturb the gulping procedure and make eating, drinking, taking prescription and breathing trouble. Dysphagiaexercises are designed toenhancing muscles and coordinatingthe nervesandmuscles involved in swallowing.The pre-experimental design was used with 60 samples who matched the inclusion criteria who were selected by purposive sampling technique.The study aims is to assess the swallowing ability before and after dysphagia exercisesamong patients with cerebrovascular accidents. Demographical variables were collected by using self- structured questionnaires and Modified Mann Assessment of Swallowing Ability Scale.The study uncovered that the pre-test mean swallowing ability score was 42.45 with a standard deviation of 8.63 among the cerebrovascular accident patients. The post-test swallowing ability mean score of 50.54% with a standard deviation of 8.23 among the cerebrovascular accident patients. The study findings concluded thatDysphagia practices which was an effective, inexpensive, simple measure for improving swallowing ability among patients with cerebrovascular accident.
Assessment of utilization of anticancer drugs in cancer centre at tertiary care hospitals in Telangana region
Authors: Praveen Kumar T  , Nadeem Ahmed  , Sravan Kumar B  , Chinna Eswaraiah M
Published: April 2020

Cancer is a life-threatening disease and is a major economic burden to families in India. Assessment of the utilization of anticancerdrugs promotes rational in using drugs.The main objective of the study was to identify theprevalence of various types of cancers, analyzing the prescribing patterns of anticancer drugs in cancer centers atthe tertiary care government hospital of Telangana. It was aProspective and observational study carried out in hospitals ofTelangana for a period of six months, which includes 300 patients. All the patients with respective to age, sex, diagnosis, and treatment, who were on anticancer prescription and were willing to give consent, were included in the study.Among 300 patients selected in our study, 111 (37 %) were males, and 189 (63 %) were female patients.170 (56.66 %) cancer cases were evident between 71 to 80 years of age. Hypertension is the major comorbidity observed in 68 cancer patients.54 drugs were prescribed for different cancers patients in our study.  The most commonly used class of anticancer agents wastyrosine kinase inhibitors (10drugs), monoclonal antibodies (10 drugs). 33 female patients were suffering from breast cancer, and Lungs cancer was found in 44 patients. Carboplatin was given to 30 (10%) patients, followed by Chlorambucil to 27 patients (9%).Assessment of utilization of Anticancer Drugs promotes education to a physician for rational drug use and can give better health care and also cost-effective treatment.
Synthesis of some novel 3- (4-ethoxyphenyl) -5- (4-substituted) -4,5-dihydro-1H-pyrazole derivatives as potent antioxidant agents
Authors: Lakshminarayanan B  , Kannappan N  , Subburaju T  , Kalaichelvan V K
Published: April 2020

Pyrazolines are the most useful heterocyclic moiety in Pharmaceutical and Chemical fields and as the most potential molecules for the design of new chemical entities. Nitrogen-containing heterocyclic compounds, pyrazolines and their derivatives showed a variety of pharmacological activities, including antioxidant properties. In the present study, eleven novel ethoxylated pyrazoline derivatives were synthesized by condensing chalcones with electron releasingethoxy group at one end and different electron-donating, electron-withdrawing groups in another end with hydrazine hydrate andalcohol. The compounds synthesized were structural elucidated by their spectroscopic studies. All the compounds synthesized were evaluated for their in vitro antioxidant potential by 2,2’-diphenyl-1-picrylhydrazyl (DPPH)and hydrogen peroxide free radical scavenging assay methods.Some of these molecules possess moderate to good antioxidant activitywhen compared to standard ascorbic acid. The compound with methoxy group (EH2) exhibits potent antioxidant activity with IC50 value of 9.02 and 9.44µg/ml in DPPH and hydrogen peroxide assay method respectively and the compound with hydroxy group (EH9) also showed potent antioxidant activity with IC50 value of 12.41 and 14.56µg/ml in DPPH and hydrogen peroxide free radical scavengingassay method respectively when compared to standard. The compounds containing electron-donating substituents were found to be good antioxidantswhen compared to standard ascorbic acid.
Improvement of econazole nitrate solubility by using surfactants and phospholipids according to optimized experimental design
Authors: Ismail Bennani  , Lamyae Yachi  , Yassir El Alaoui  , Aicha Fahry  , Nawal Cherkaoui  , Abdelkader Laatiris  , Jaouad El Harti  , Younes Rahali
Published: April 2020

The main purpose of this study is to improve and boost the solubility of Econazole Nitrate in water using phospholipid and surfactants, until it becomes possible to evaluate the utility of a mixture design in order to determine the optimal composition of non-ionic surfactants and phospholipids needed to obtain a significant improvement in the solubility of Econazole Nitrate in water. The design of experiments approach was tested using a mixture design of Lipoïd 75® as phospholipid and Econazole Nitrate, Tween® 80 and Solutol®HS 15 as surfactants,. Solubility was determined by the analysis of samples absorbance at 225 nm. and the measurement size of particles conducted using a Dynamic Light Scattering at the maximum point of solubility. The final results displayed an improvement in solubility with a statistically significant increase in many tested mixtures. Analysis of the design space showed that, the solubility of Econazole Nitrate is importantly affected by the concentration of surfactants. The best obtained test encloses 1% Econazole Nitrate, 2% Tween® 80, 0.5% Lipoid 75®, 2% Solutol®HS 15 and water q. s. for 100% w / w. Our study has demonstrated that optimized experimental design determines the proportions and the effects of every component based on a limited number of experiments.
In-vitro antibiofilm activity of selected medicinal plants against Staphylococcus aureus biofilm on chitin flakes as substrate
Authors: Baishya Rimashree , Banerjee Soma
Published: April 2020

The aim of the study is to assess the antibiofilm activity of ethanolic extracts of few Indian traditional herbal plants against Staphylococcus aureus biofilm along with phytochemical analysis of plant extracts and identification of active compounds. Broth micro-dilution method was followed for minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) study of the plants against Staphylococcus aureus ATCC 25923. Chitin was used as a substrate for biofilm formation and antibiofilm activity of plant extract was investigated. Scanning electron microscopy (SEM) and Fourier-transform infrared spectroscopy (FT-IR) of the chitin flakes were analysed to determine the inhibitory effect of the plant extract on Staphylococcus aureus biofilm. Curcuma longa showed the best antibacterial activities where MIC and MBC were 0.4 mg/ml and 1.60 mg/ml respectively. Viability cell counts of both planktonic and sessile condition of Staphylococcus aureus showed that C.longa ethanolic extract have an antibiofilm activity. The major compounds of C.longa extract was found to be curcumin, which responded for antibiofilm activity against S. aureus. Curcuma longa rhizome and its active compound curcumin can be a potential natural source of antibiofilm agents against infectious biofilm forming Staphylococcus aureus.
Adequacy of Olmesartan monotherapy versus cotherapy in patients with essential hypertension
Authors: Rada Feryal Hashim
Published: April 2020

Olmesartan is a class of an angiotensin II receptor blocker drugs used for the treatment of hypertension. The aim of this crossover clinical study is to evaluate the safety and effectiveness of Olmesartan monotherapy compared to Olmesartan plus amlodipine co-therapy in patients with essential hypertension. An entire of eighty-three patients (45 males, 38 females) their age ranging  (45-55 ) years with essential hypertension enrolled from Al Yarmouk hospital /Iraq for this study. After reaching the point of inclusion criteria, they treated with Olmesartan medoxomil 20 mg daily for a period of two months, then after two weeks of wash off, they treated with Olmesartan 20 mg daily plus amlodipine 10 mg daily for another two months. Blood pressure (systolic and diastolic) and clinical laboratory tests that include fasting blood levels of glucose, insulin, lipid profile, adiponectin, leptin, cystatin c and creatinine were obtained and studied at baseline (prior treatment), after two months of Olmesartan monotherapy and after two months of Olmesartan co-therapy.The statistical analyses of the data in patients using Olmesartan co-therapy versus Olmesartan monotherapy showed more effectiveness in decreasing blood pressure, better in reducing the blood levels of glucose, insulin, total cholesterol, triglyceride, and leptin, superior in elevating the values of insulin sensitivity index and in elevating the blood levels of adiponectin. Concisely, the addition of amlodipine to Olmesartan treatment ameliorated insulin sensitivity and adiponectin level and attenuated the leptin level.
SARS-CoV-2 / 2019-Novel Corona Virus: An Epidemic to Pandemic
Authors: Argha Sarkar  , Mayuri Kundu  , Padarthi Venkataramana  , Pinaki Chakraborty
Published: April 2020

An unexpected outbreak of pneumonia of unfamiliar aetiology in Wuhan,Hubei, China was reported in December 2019. World Health Organization identified the pathogen and named it COVID-19. COVID-19 madethe world go through a cisis. The impact of this viral disease is now an issue of major concern. Respiratory infections, dry cough with fever are the major symptoms which are due to beta coronavirus, namely Severe Acute Respiratory Syndrome corona virus 2 (SARS-CoV-2). Within a short spell, COVID-19 spread all over China. Since January to today 24 March 2020 this epidemic turned into pandemic with continuous rise of cases and deaths. Italy, Germany, Spain, USA, Iran, France are the countries where the disease is spreading in a community level and rest of the countries over the globe the positive cases are also comingin.  As the disease is communicable, it is highly necessary to take measures before it starts spreading in countries like India where the population is very high. The treatment of this severe acute respiratory syndrome corona virus 2 is not clear so far. Prevention is the only way to stop spreading this fatal disease. In view of this, the total state of knowledge regarding COVID-19 and the suggestive prevention are discussed by considering countries (considering India) where the population is high and this pandemic has just started spreading.
Effect of cooking methods on nutritional composition and antioxidant properties of lotus (Nelumbo nucifera) rhizome
Authors: Chen S.Y. , T.M. Tengku Rozaina
Published: April 2020

Lotus (Nelumbo nucifera) rhizome possessed abundant nutrients such as vitamin C,
minerals and antioxidants. The consumption of lotus rhizome is limited in Malaysia due to
limited information on its nutritional values. Cooking or heat treatment may cause
nutritional changes in the food, however, there is a lack of study on the effect of cooking
methods on nutritional contents of lotus rhizome. In this study, the effects of cooking
methods (steaming, boiling and deep-frying) on nutritional composition (proximate,
vitamin C and minerals) and antioxidant properties (total phenolic content, total flavonoid
content, DPPH and ABTS scavenging activity) of lotus rhizome were investigated.
Results showed that boiling significantly increased moisture and crude fibre but decreased
ash, crude fat and crude protein contents of lotus rhizome. Meanwhile, deep frying
significantly reduced moisture and increased ash, crude fat, crude protein, crude fibre and
carbohydrate contents of lotus rhizome. Steaming induced no significant changes in
moisture, crude protein, crude fat, crude fibre, carbohydrate, vitamin C and mineral
(potassium, zinc and copper) contents when compared to the raw lotus rhizome. Boiling
significantly reduced the amount of vitamin C while deep frying caused a significant
reduction in total phenolic content, total flavonoid content and antioxidant activity for
both ABTS and DPPH assays of lotus rhizome. In conclusion, steaming would be the best
cooking methods for lotus rhizome while deep frying is not recommended to retain the
nutritional composition and antioxidant properties of lotus rhizome.
O uso das afetividades em Wallon e as práticas socioeducativas de um projeto social em São Gonçalo - RJ
Authors: Ferreira Arthur Vianna , Lopes Lucas Salgueiro
Published: April 2020

Este artigo tem como objetivo identificar a relevância da afetividade nos processos de ensino-aprendizagem em uma instituição socioeducativa não escolar. O material de análise dessa pesquisa foi construído a partir da escrita de diários de campo que relatam as visitas realizadas ao projeto Luxo de Vida durante o ano de 2017. Esses diários foram escritos com base na observação de campo a partir da fenomenologia de Edmund Husserl. Assim, busca-se fazer uma articulação do material com os conceitos de Henri Wallon, tal como uma análise histórica e social do contexto local da ONG, localizada no Complexo do Salgueiro. A partir dos resultados dessa pesquisa, concluímos que o uso de uma afetividade positiva, com práticas de encorajamento para maior autonomia do aluno, gera resultados mais eficazes no processo de aprendizagem, em especial, quando respeitado o tempo de desenvolvimento e o contexto social na qual o aluno está inserido
Vortex-induced vibration of elastically connected multiple circular cylinders in a side-by-side arrangement in steady flow
Authors: Kaja Kalyani , Zhao Ming
Published: April 2020

Vortex-induced vibration (VIV) of multiple circular cylinders elastically connected together in a side-by-side arrangement subject to steady flow is investigated numerically at a low Reynolds number of 150 and a mass ratio of 2. Simulations are conducted for two-, five- and ten-cylinder systems over a wide range of reduced velocities. The aim of the study is to identify the high-amplitude response range of the reduced velocity for the multiple degree of freedom vibration system and identify the difference between the responses of the single- and multiple-degree-of-freedom vibrations. Unlike the single cylinder case, distinct lock-in between the response frequency and any of the structural natural frequencies in a wide range of reduced velocity is not observed in the multiple-cylinder cases. Instead, the response frequency increases continuously with increasing reduced velocity. High response amplitudes are found when the response frequency is between the first and the highest modal frequencies. In a multiple-cylinder system, the single-mode response, where the vibration is dominated by one mode, can be only found in low reduced velocity range. In the single-mode branch, the dominance of a single mode shape in the response can be clearly identified except at the boundary reduced velocity between two modes. The maximum response amplitude occurs in the multiple-mode response and interaction between the vortices in the wake of the cylinders is strong when the response amplitudes are high.
3D model simulating the hydro-mechanical state of unsaturated and deformable material during hot air drying
Authors: Hassini Lamine
Published: April 2020

A three dimensional model to predict the hydro-mechanical state of unsaturated and deformable material during hot air drying has been proposed. The material viscoelastic behaviour was formulated using Bishop’s effective stress theory for partially saturated material using the liquid saturation as the Bishop parameter. The hydro-thermal and mechanical equations were coupled by the fluid pressure and the solid matter velocity. The model was applied to a deformable material (innovative clay-cellulose fibers composite) subjected to convective drying. A generalized Maxwell model with five elements, whose parameters were measured experimentally and correlated to water content was used to describe the material’s viscoelastic behavior. The hydro-thermal part of the proposed model was validated on the basis of a  comparison of experimental and simulated drying rate curves. The Von Mises stress was simulated and compared to the experimental tensile strength in order to predict the time and the region of material failure.  For a drying process at95°C, the region of failure risk was identified. The failure may occur on the lateral surface of the slab in contact with air at a drying time of 2.5h.
Combining Methods to Estimate Ecosystem Integrity and Ecosystem Service Potentials and Flows for Crop Production in Schleswig-Holstein, Germany
Authors: Zelený Jakub , Bicking Sabine , Dang Kinh Bac , Müller Felix
Published: April 2020

Human well-being is highly dependent on nature, especially with respect to food provision. This study has been developed in the ecosystem service framework and focuses on the evaluation of ecological integrity as a basefor the capacity of Schleswig-Holstein to provide ecosystem services. The ecosystem service potential is assessed based upon a Bayesian belief network and the study area’s soil fertility. The respective service flow is estimated from official regional statistics, and is represented by the total harvested biomass for food, fodder and energy. The spatial distribution of six different ecological integrity variables and the crop production potentials and flows are compared and interpreted with respect to the characteristics of the main landscape regions within the study area. The results indicate a trade-off between the actual crop production and the underlying ecological integrity and service potentials. This trade-off is strongest in case of croplands, while it gradually diminishes in grasslands and forests. Based on the results, conclusions about the relation between ecosystem services and ecological integrity are drawn. The findings of the study can be used to support the development of sustainable land management strategies, which aim to harmonize agricultural production and environmental conditions.
Ocorrência de internações por condições sensíveis à atenção primária (ICSAP) no município de Campinas, São Paulo: associação com os atributos necessários a atenção primária.
Authors: Fonseca Marcia Regina Campos Costa da , Santana Laura Alejandra Matulevich , Rojo Maria Eduarda Ribeiro
Published: April 2020

Introdução: As Internações por Condições Sensíveis à Atenção Primária (ICSAP) são um indicador indireto da efetividade do primeiro nível de atenção à saúde. Objetivo: Analisar a ocorrência de ICSAP e verificar a associação, nas unidades de saúde com maior e menor coeficiente ICSAP, com os atributos necessários à atenção primária à saúde (APS). Método: Estudo descritivo, sendo a fonte de dados das ICSAP, o Sistema de Informações Hospitalares-Campinas, 2015, e a fonte de dados referentes aos atributos das unidades de saúde, a entrevista aplicada à equipe de saúde, sendo um questionário avaliando a adequação da estrutura, baseado no Instrumento de Avaliação Externa do Programa Nacional de Melhoria do Acesso e da Qualidade da Atenção Básica (PMAQ) e o outro avaliando a adequação do processo de trabalho, através do Primary Care Assessment Tool PCATool-Brasil.  Para as análises estatísticas foi utilizado o teste de Wilcoxon-Mann-Whitney, sendo 5% o nível de significância adotado nos testes. Resultados: As ICSAP corresponderam a 15,6% do total de internações do município, sendo mais frequente entre os idosos (48,6%).  Não se observou significância estatística entre as ocorrências de ISCAP e os atributos da APS. Conclusão: Os achados deste estudo auxiliam na avaliação da atenção básica no Brasil.
Fuzzy Neural Technique Based Dynamic Voltage Restorer for Power Quality Enhancement Under Different Voltage Variations
Authors: Abdul-Jabbar Fathel Ali  , Wael Hussein Zayer  , Samhar Saeed Shukir
Published: April 2020

Abstract— Recently a large interest has been focused on power quality field due to: disturbances caused by non-linear loads, Increase in the number of electronic devices and renewable energy sources. Power quality measures the fitness of the electric power transmitted from generation to the industrial, domestic and commercial consumers. In a power system voltage distortion introduced by harmonics and voltage sags are the most severe affecting power quality, because of both consumers and utilities are affected by these disturbances. Different methods to enhance the power quality but the custom power device is the most effective and efficient method. One of which is the use of Dynamic Voltage Restorer (DVR). The performance of the DVR based on Fuzzy Neural controller to restore the load voltage to its nominal value under different fault conditions and power disturbances is presented in this paper. Simulation results are carried out using MATLAB/SIMULINK program. The faults and disturbances are initiated at 0.8s and kept till 0.95s.
Influence of Changing Porosity and Height of Fins on Thermal Performance of The Metal Foam Heat Sink: Numerical Investigation
Authors: Abbas J. Jubear  , Aqeel Mtasher Uglah
Published: April 2020

Abstract— With the major advances in technology, the extreme need for more powerful and efficient electronic devices and equipment has increased, that is requiring more heat generation as a result. So, it is necessary to find a cooling method commensurate with heat generated. This leads to the use of the foam heat sink which is considered as one of more powerful cooling methods for this purpose. The target of this work is to numerically investigate the impact of changing the porosity and the ratio between height of the fin respect to its length on base temperature and heat transfer coefficient in the case of natural convection conditions. The dimensions of the foam fins were 100 * 10 in mm (length * width) and the spacing between fins was 8 mm, while the height of fins was variable with ratio ranging from 0.2 to 2.4. The porosity of model was changing from 0.95 to 0.71 with fixed pore density of 10 PPI. The investigations have been performed by using ANSYS Fluent software (R16.1) and the model of a local thermal non-equilibrium (LINE) has been used in the analysis where, the temperature of the solid part in foam matrix and the fluid are solved individually in energy equation. The heat fluxes were various from 4 to 30 W, and air has been used as a working fluid. The results showed that the average improvement in base temperature of the heat sink is 16.7 %, and the maximum enhancement of heat transfer coefficient reaches about 21.3%, when the porosity reduced from 0.95 to 0.79. The highest enhancement in base temperature and heat transfer coefficient obtains when the height to length ratio is (2.2) and estimated by 30 % and 83.8% respectively, compared with the ratio of (0.2).
tugas audit sistem informasi ika farhan tama npm 195100042P
Authors: Ikafarhantama
Published: April 2020

AUDIT SISTEM INFORMASI MENGGUNAKAN FRAMEWORK COBIT 4.1 PADA PT ANEKA SOLUSI TEKNOLOGI
Genetic variations and drug repurposing provides key insights into the disruption of the SARS COV2
Authors: Panda Gayatri , Mishra Neha , Ray Arjun
Published: April 2020

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV- 2) is mediated via the initial interaction of the virus’s spike (S-) protein with a human receptor protein called angiotensin-converting enzyme 2 (hACE2). Interference in this association can have immense therapeutic importance. We used an in-silico combinatorial approach involving homology-based protein modeling, protein-protein docking, binding energy estimation and virtual screening techniques to probe for genetic variations and drug molecules for disruption of the hACE2-CoV2 interaction. Our results identified Ser19Pro variation on hACE2 showed similar structural stability to the native protein while having a destabilizing effect in the hACE2(Ser19Pro)-S-protein complex. We also found several FDA-approved drug molecules that can potentially induce competition-mediated destabilization of the hACE2-CoV2 complex. In conclusion, these findings provide critical insights for intervention strategies targeting the pathogenicity of SARS-CoV-2.
دوخ د لارستا كارى نةتةواودا
Authors: Ali Vian Ibrahim
Published: April 2020

Case, as a grammatical topic, is investigated in Kurdish Grammar textbooks in a rather broad sense, and most of the work on that topic is descriptive However,the study of Case pattern in relational clauses hasn’t been investigated yet Therefore ,this paper is an attempt to study Case in relational clause ,which in our view ,will be an important contribution in the field of Kurdish syntax in general, and the subject of Case in specific The study hypothesizes that the subject NP and the complement NP in these clauses are assigned Case structurally by the functional head AGR, under government
the origin of angular momentum:Equilibrium between Orbital Plane and Galactic Plane
Authors: saxena jagmohan
Published: April 2020

kepler law does not provide solution to axis motion of planets or celestial bodies it is unsolved mystery of space science how and why galaxies moves? why planets do axis movement it provides the solution Jagmohan saxena given a solition to मस्तर्य4
Review of the antiviral activity and pharmacology of monoglycerides and implications for treatment of COVID-19
Authors: Aldridge Mira
Published: April 2020

Monoglycerides are a class of lipids derived from fatty acids with well established antiviral properties. Monoglycerides are widely used in food processing, cosmetics and in nutritional supplements. This review examines the biochemical and pharmacological properties of monoglycerides and fatty acids as they pertain to COVID-19 pathogenesis. Information on monoglycerides, fatty acids and COVID-19 is presented with sources gathered through PubMed, Elsevier, JSTOR, Oxford University Press Medicine Archive, Wiley, MedRxiv and Google. The antiviral activity of monoglycerides has been documented since the 1970's. In vitro studies have shown that viral concentrations of enveloped viruses were reduced by over 10,000 fold in the presence of monoglycerides such as glycerol monolaurate. Moreover, glycerol monolaurate is widely available and generally recognized as safe (GRAS) by the FDA. The aim of this review is to present an evidence based case for further investigation into this class of compounds for the potential treatment of COVID-19.
tDCS and tinnitus A meta analytic exploration into efficacy and optimization
Authors: Cates Alexander , Davies Evan
Published: April 2020

Millions of Americans suffer from tinnitus, or ringing of the ears. Despite its prevalence, treatment for tinnitus is limited, with most approaches focusing on making the symptoms tolerable, instead of treating the underlying neurological causes. Recently however, brain stimulation techniques, such as transcranial direct current stimulation (tDCS), have emerged offering a new method to interact with the brain and offering hope as a new approach to treating the underlying causes of tinnitus, not just making the symptoms tolerable. In the present meta-analysis, we analyzed the results from 17 controlled trials and 5 uncontrolled case studies to determine the efficacy of tDCS for treating tinnitus. Additionally, we performed sub-analyses to test how different tDCS parameters may alter the efficacy of treatment. Overall, we found a small but significant effect (Overall Hedges g of 0.17 (95% CI 0.09-0.25)) of tDCS on tinnitus symptoms. However, mechanistically we found that targeting the DLPFC improved symptoms significantly more than other targets, including targeting the auditory cortex directly. This along with the subjective outcome measures currently available, suggest that while tDCS does offer a benefit to treating the symptoms, it does not appear to treat any underlying causes. It is the opinion of the authors therefore that tDCS should be used in addition to traditional interventions to make the symptoms more tolerable. As covered in the discussion, future research should explore more objective measures of tinnitus in order to better assess the efficacy of tDCS and other brain stimulation methods, with the hope of developing a causal treatment of tinnitus.
A cost-effective preventative approach to potentially save lives in the coronavirus pandemic, jointly using Vitamin D, Curcumin, and Vitamin C. Authors Bakare T A and Soar J S
Authors: Soar Jagjit S
Published: April 2020

he current COVID-19 pandemic now believed to be based on the mutation of the SARS-CoV virus (first reported in 2002) to SARS-CoV-2 emerging in 2019, is naturally causing extreme worry and concern around the world with sometimes mixed and incoherent messages on how to deal with it. There is a plethora of information from previous epidemics caused by other coronaviruses such as severe acute respiratory syndrome, SARS (2002) and Middle East respiratory syndrome MERS (2012) from which we can extrapolate guidance on how to deal with the current pandemic. In the current absence of specific pharmaceutical agents, we propose assessing the extended tools that we already possess in our biological armoury to combat, prevent and control the spread of this virus. Using a set of precise criteria to locate such possible contenders, we conducted literature searches to find compounds that met these criteria. We have now reduced this to a shortlist of three agents that may be the best candidates. We propose vitamin C, vitamin D and Curcumin fit our criteria well. These compounds are widely available to the general public. They are available online and over-the-counter as supplements. Otherwise healthy individuals are safely able to self-administer these agents as a prophylactic to protect themselves and to enhance their immune response. This would be especially desirable for the elderly and at risk groups. These agents can also be used as adjunct therapy, particularly for those who may have early symptoms. This preventative therapy could be implemented whilst awaiting specific pharmaceutical drugs to emerge as a treatment for COVID-19. Our suggested compounds are a highly cost-effective way to potentially reduce the mortality that is regretfully mounting as a result of COVID-19 infection. The biological mode of action and the dosing of these compounds are summarised.
Comparison of kernel functions of support vector machines: A case study for the solar cell output power prediction
Authors: NURWAHA Deogratias
Published: April 2020

Four kernel functions of support vector machines (SVM), namely, radial basis function, sigmoid function, linear function and polynomial function, were applied for the prediction of solar cell output power. Two types of SVM model such as epsilon-SRV and nu-SVR were chosen for each kernel function. Measured values of temperature T (°C) and irradiance E (〖kWh.m〗^(-2)) were used as inputs and solar cell output power P (kW) was used as output. The accuracy of each kernel function was evaluated using well known statistical parameters. Radial basis function using nu-SVR and polynomial function using epsilon-SVR provided similar and better results than other kernels. However, polynomial function has taken more analysis run time while radial basis function used more number of support vectors than other kernels. They may be more computationally expensive.
A comparative analysis of four-pole brushless DC motors with different slot and winding arrangement based on THD values
Authors: OCAK Cemil , DALCALI Adem
Published: April 2020

Brushless DC motors (BLDC) are widely used in variable speed drive applications. Nowadays the relationship between the number of poles, slots and winding arrangements in BLDC motors continues to be a very challenging topic. The main objective of this work was to develop and compare four-pole BLDC motors with different slot numbers (6, 12 and 15) and winding arrangements. Three-dimensional finite element analysis (FEA) was conducted to characterize the proposed designs. The Total Harmonic Distortion (THDv) which tells the amount of harmonics present in the voltage have been obtained and compared based on the different slot numbers and winding arrangement. In the study, an extensive investigation of the THDv values in four-pole BLDC motors having different slot and winding configurations has been carried out. From the simulated results it is evident that the lowest THDv and corresponding sinusoidal back emf can be obtained by implementing 15 slots within four-pole designs. The performance values have been examined comparatively by analysing the motors at the rated condition.
Evaluation of biodiesel produced from tea seed oil in terms of fatty acid components
Authors: AYDIN Fatih , ÇALIŞKAN Sena
Published: April 2020

Factors such as increased energy demand, environmental pollution, energy security and ensuring energy sustainability have accelerated the search for alternative energy. The interest in renewable energy sources has increased with the decrease of oil, oil crises and the increase of environmental awareness. Biodiesel is an alternative energy source that is renewable with chemical methods from vegetable and animal oils. It does not cause CO₂ release and greenhouse effect compared to petro diesel. It is an environmentally friendly fuel. The tea seeds used in this study have been selected as an alternative from the idle tea seed for biodiesel production without harming the cooking oil stock in Turkey, which is an agricultural country where tea growing and tea consumption is increasing. Biodiesel production was investigated with the transesterification method, which is a method that reduces the production cost and viscosity of the oil obtained from tea seeds by using less chemicals to bring the idle tea seeds to the economy in Turkey and in the world.
A Systematic Review of Role and Responsibilities of Head Teachers at Primary Level in District Shaheed Benazirabad
Authors: Shaikh Muhammad Ali , Deraj Mahboob Ali , Sahito Zahid Hussain
Published: April 2020

The purpose of this research study was to review the expected role and responsibilities to be played by headteachers and done in reality at the primary school level in District Shaheed Benazirabad. It has been observed that headteachers in public schools at the primary level are not performing as per the need of the time. For the purpose, a tailor-made questionnaire was distributed among randomly selected headteachers. The quantitative research approach was used to solve the query. The results indicate the lenient approach of headteachers towards their duties.
Exploring the Influence of Unemployment on Criminal Behavior in Punjab, Pakistan.
Authors: Khaliq Nouman , Shabbir Muhammad , Batool Zahira
Published: April 2020

The main objective of this research was to investigate the effect of unemployment on criminal behavior. A multistage sampling technique was used for the selection of a sample of 400 respondents who have ever committed a crime. A well-designed and the pre-tested interviewing schedule was used to collect information from the respondents in randomly selected district jails of Punjab, Pakistan. Descriptive analysis shows that majority of the respondents was young and married. Around onefourth of the respondents were illiterate and about the same proportion had primary level education. Two-fifth of the respondents had less than Rs. 20,000 monthly family income. Multivariate analysis revealed that unemployed respondents had 30 percent more chances to commit the crime as compared to the employed respondents. Thus the set hypothesis that unemployment is significantly related to criminal behavior of the respondents is upheld
COMBINED EFFECTS OF QUERCETIN AND MODULATORS OF REDOX SENSITIVE FACTORS ON THE INDICATORS OF SYSTEMIC INFLAMMATORY RESPONSE, CARBOHYDRATE AND LIPID METABOLISM IN RATS EXPOSED TO INTRAPERITONEAL AND INTRAGINGIVAL ADMINISTRATION OF SALMONELLA TYPHI LIPOPOLY
Authors: Yelins’ka A.M. , Kostenko V.O.
Published: April 2020

The experiment on 70 white rats was designed to investigate the effects of a water-soluble form of quercetin and modulators of AP-1 and Nrf2 transcription factors on the blood indicators of the systemic inflammatory response (SIR), and carbohydrate and lipid metabolism under the conditions of intraperitoneal and intra-gingival administration of S. typhi lipopolysaccharide (LPS). The animals were divided into 7 groups: the 1st group consisted of intact rats; the 2nd group included animals exposed to combined systemic and local administration of LPS - pyrogenal; the 3rd, 4th and 5th groups included the animals who were respectively injected with water-soluble complex of quercetin and polyvinylpyrrolidone (corvitin) in a dose of 100 mg/kg (10 mg/kg in terms of quercetin), an inhibitor of activation of AP-1 SR 11302 (in a dose of 1 mg / kg) and Keap1 / Nrf2 / antioxidant-responsive element (ARE) signaling pathway inducer epigallocatechin-3-gallate (EGCG, in a dose of 21.1 mg / kg) 3 times a week, starting on the 30th day since the experiment modeling. The 6th and 7th groups of the rats were subjected to combined effects of quercetin + SR 11302 and quercetin + EGCG, respectively. The study has demonstrated the combination of quercetin and SR 11302, or EGCG, in systemic and local administration of S. typhi lipopolysaccharide more effectively prevents the production of ceruloplasmin, a SIR marker, by-products of lipid peroxidation in rats’ blood, as well as increases its antioxidant potential compared to the separate application of these drugs. The combination of quercetin and SR 11302, or EGCG, under the experimental conditions has been found out to more effectively correct carbohydrate metabolism disorders (hyperinsulinemia, insulin resistance) than this occurs under separate usage of the agents, but does not reveal significant synergism in the correction of dyslipoproteinemia.