bluuebunny/crossref_metadata_2025 huggingface dataset:
Domínio, Crise e Emergência de Paradigmas: discursos sobre as ciências na Ciência da Informação
Authors: Francelin Marivalde Moacir
Published: April 2023

Apresenta e analisa os principais eventos que caracterizaram os chamados paradigmas dominantes, paradigmas em crise e paradigmas emergentes. Identifica e discute a presença e os pontos de vista sobre esses paradigmas na Ciência da Informação. O objeto, inicialmente selecionado, é o contexto que discursa sobre a ciência. Paradigmas dominantes, revoluções científicas, crise dos paradigmas e paradigmas emergentes são os principais temas desse discurso. O artigo pergunta sobre a forma como esses temas são apresentados na Ciência da Informação. Contextualiza a pergunta de pesquisa na presença do livro Um discurso sobre as ciências na área. Parte da hipótese de que a literatura da área objetiva apresentar alguns dos paradigmas emergentes, sem especificar a questão do senso comum. Pesquisa exploratória e reflexiva, baseada em revisão bibliográfica. O artigo contribui para refletir sobre as propostas dos paradigmas emergentes no contexto de uma ciência pós-moderna.
Redes Sociais como Ferramentas de Comunicação: uma síntese teórica
Authors: Faoro Roberta Rodrigues , Abreu Marcelo Faoro de , Demarchi Mateus
Published: April 2023

As redes sociais possuem uma grande quantidade de usuários, deste modo, a presença das organizações nas redes sociais é essencial, para divulgar sua marca e principalmente estabelecer interações com seus clientes. Neste sentido, o propósito desta síntese é discutir as redes sociais como ferramentas de comunicação entre as empresas e seus clientes. Busca-se demonstrar o uso de redes sociais para comunicação bidirecional, o uso de redes sociais produzindo conteúdo personalizado e o uso de redes sociais para compartilhamento de informações, experiências, enfim, de conhecimento. A discussão apresentada nesta síntese limita-se ao cunho teórico sendo, portanto, de fundamental importância a realização de estudos empíricos com vistas à validação ou rejeição das proposições aqui apresentadas.
A Redefinição da Biblioteca Universitária à Luz dos Paradigmas da Biblioteconomia e Ciência da Informação: um estudo de caso
Authors: Santa Anna Jorge , Costa Maria Elizabeth de Oliveira
Published: April 2023

Apresenta as contribuições advindas da Biblioteconomia e Ciência da Informação quanto às práticas profissionais realizadas em uma biblioteca universitária. Objetiva identificar os pontos paradigmáticos observados na referida unidade de informação, a partir dos paradigmas que sustentam essas duas áreas do conhecimento, discorridos na literatura. Com esse propósito, o estudo caracteriza as bibliotecas universitárias na modernidade; apresenta os paradigmas da Ciência da Informação e Biblioteconomia; e, por fim, investiga a política institucional, os produtos e serviços realizados nessa biblioteca, identificando pontos paradigmáticos que os sustentam. Por meio da revisão de literatura e da análise e discussão dos dados coletados em campo, constatou-se que a maioria dos paradigmas adotados pela biblioteca universitária pertence à Biblioteconomia, tais como: foco no acervo documental, pouca preocupação com o usuário, maioria dos itens centra-se em livros impressos, atuação tecnicista, atividades de cunho meramente informacional e pouca interação entre setores e gestão dos fluxos de informação. Apenas dois paradigmas são frutos da Ciência da Informação, a saber: preocupação acentuada com a recuperação da informação e tendência à informatização. Sugere-se a elaboração de um plano de ação, oriundo de um planejamento bem estruturado, a fim de reformular a política institucional, redefinindo e ampliando as práticas bibliotecárias, tendo como base, a fusão dos paradigmas dessas duas áreas.
Interfaces em Arquivologia, Biblioteconomia e Ciência da Informação: abordagem temática e atuação profissional
Authors: Souza Edivanio Duarte de , Araujo Ronaldo Ferreira de
Published: April 2023

Editorial, v. 4, n. 3.
La teoría de la difusión de las innovaciones en la cultura zenú
Authors: Restrepo-Arango Cristina
Published: April 2023

Aplica la teoría de la difusión de las innovaciones a la literatura producida sobre la cultura zenú. Fueron identificados 154 documentos publicados desde 1875 hasta junio de 2018 por 170 autores diferentes. La teoría de la difusión de las innovaciones identifica cinco categorías de adopción de una idea. Primero, innovadores; segundo, adoptantes iniciales; tercero, mayoría temprana; cuatro, mayoría tardía; y quinto, rezagados. Estas categorías se identificaron en esta literatura; por ejemplo, se encontraron en el grupo de los innovadores cuatro autores; en el grupo de los adoptantes iniciales 23 autores; en el grupo de la mayoría temprana 58 autores; en el grupo de la mayoría tardía 58 autores; y en el grupo de los rezagados 27 autores.
Creating a School Library with Impact
Authors: Roche Caroline , Band Barbara , Cavender Nick , Chambers Lucy , Everall Annie , Krajewski Ellen , Pavey Sarah
Published: April 2023

School libraries are facing numerous challenges in the twenty-first century. The number of professionally qualified staff working in schools has fallen in recent years and, increasingly, new appointments to library positions are sorely lacking the skills and knowledge needed. While there are a number of resources available detailing how to improve your school library once it is up and running there is a dearth of books that deal with the absolute basics in a practical manner, looking at the role from the first day.

Creating a School Library with Impact: A Beginners Guide is an introductory manual for anyone entering or looking to enter the exciting world of school librarianship in primary or secondary school settings. It provides readers with everything they need to know and understand from day one from author visits, social media, reading schemes, information literacy, evaluating your library, the physical layout of your room and much more, providing an invaluable guide to those first few years in the role.
EFFECT OF SHORT AND LONG DURATION NADA YOGA MEDITATION ON HEART RATE OF PARA YOGA ATHLETES
Authors: Tewani Dakshata , Singh Vikram , Joshi Navdeep , Singh Surender
Published: April 2023

Introduction: Heart rate is a fairly good indicator of health-related physical fitness and is often used by fitness and yoga trainers before, during, and after their training sessions. “Divyang Jana”, a term often used to refer to persons with disabilities (PwD) are equally and sometimes more prone to having elevated heart rates because of external and internal conditions beyond their control. This study was undertaken to evaluate the role of NADA Yoga Meditation (22 minutes) in improving the important physiological parameter heart rate (HR) in visually impaired (VI) para yoga athletes of Uttarakhand.Method: 52 para-yoga athletes were divided into two groups of which one group did Meditation and the other did not. HR-1 (pre-intervention, HR-2- after one week, and HR-3 after 2 weeks of the intervention were measured in beats per minute offline (first week) and online (second week) NADA meditation training.Result: At the end of the study significant decrease in HR-2 and HR-3 was seen in the para yoga sports persons who practiced Meditation as compared to the non-practicing group (control group) after controlling for the covariate HR-1 (pre-intervention heart rate).Discussion: The results were interpreted using MANCOVA and concluded that NADA yoga meditation was effective in reducing the heart rate mediated anxiety levels of yoga para-athletes in just 2 weeks and was found to be effective not only in just a week but also after 2 weeks of NADA Yoga meditation training done for 22 minutes each. Further, it can be argued that NADA yoga meditation may modulate the physiological response to stress via neurohumoral activation as displayed by the fairly good indicator namely heart rate.
Regionalist Voting Behavior in Administrative Border Areas: Focusing on the Yeongnam-Honam border area
Authors:   Institute of East and West Studies Yonsei University, Park Jung Heui , Lee Jae Mook
Published: April 2023

This paper examines the regionalist voting behavior in the geographically adjacent Yeongnam-Honam border area, although the administrative districts at the metropolitan level are different. More specifically, this study aims to empirically verify the regionalist voting relaxation phenomenon in the Yeongnam-Honam border area, where emotional communication is possible through daily life sharing and various friendly exchanges. To do so, collective data are examined with counting data for each voting district for presidential and general elections held in Korea since 2000, and voter support patterns of regional dominant parties in the region are analyzed. As a result of the analysis of the collective data, First of all, it was possible to verify the regionalist voting relaxation phenomenon withdrawing from support for regional dominant parties in 15 of the 26 Eups and Myeons as the subject of analysis of the Yeongnam-Honam border area belonging to 9 Sis and Guns. Through this, it was validated that “Honam in Yeongnam, Yeongnam in Honam” actually exists. However, it was analyzed that this regionallist voting relaxation phenomenon did not affect between neighboring Eups and Myeons. Second of all, it was confirmed that the possibility that various friendly affairs and geographical or topographical influences could affect regionalist voting behavior. The intensity of relaxation phenomenon was strong in which exchanges such as sisterhood relationships and friendly activities between neighboring Eups and Myeons were held, or in areas without topographical obstacles such as mountains and rivers.
Descriptive analysis of the elevation in the third time of volleyball through the "Tracker" program
Authors: Bucio-Ramos I  , López de la Rosa LE  , Flores-Flores A  , Zamora-Navarro A  , Rivera A
Published: April 2023

In the game of volleyball, the correct elevation of the ball for offensive shots is essential to exert an adequate ball hit and achieve points in favor. The objective of the present investigation was to establish a range in the elevation of the third time towards position 4 to improve the attack in volleyball players. For this investigation, a protocol was created that equalizes the conditions and executions that are carried out during an official volleyball match, this protocol was applied to 13 players in the position of male lifter from different selective teams in Puebla city. The method of observation and measurement by videometry was used and 13 elevators from the state of Puebla selected in a non-probabilistic way were compared, each one made 10 elevations as established by the protocol, each one of the subjects to be studied was recorded and each one was cut video to a direction of 3 to 5 seconds with the help of the online video trimmer, once the cuts were made, it was analyzed with the help of the "Tracker" program that analyzes the parabolic shot, as is the elevation in volleyball, this program locates the ball by points and with a Cartesian plane as well as with its respective calibration offers numbers in meters according to each point that the program locates. With the data obtained, the range for elevation can be known and thus the coach can have one more tool on how to evaluate his player in the point guard position.
Case report: Bilateral upper urinary tract tumor causing obstructive anuria
Authors: Nabil ALAOUI MHAMMEDI  , Othman Chama  , Mostafa Ahssaini  , Soufiane Mellas  , Jalal Eddine El Ammari  , Mohamed Fadl Tazi  , Jamal Mohammed El Fassi  , Hassan MY Farih
Published: April 2023

Bilateral upper urinary tract tumors refer to the presence of cancerous growths in both kidneys or ureters. This condition is relatively rare, and diagnosis typically involves imaging tests such as CT scans or MRIs. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches, depending on the stage and location of the tumors. Prognosis varies depending on several factors, including the type of tumor, the patient's overall health, and the extent of the disease at the time of diagnosis. Early detection and treatment are essential for improving outcomes in patients with bilateral upper urinary tract tumors.
Factors related to compliance of Covid-19 health protocols among restaurant employees, Mandonga District, Kendari City, Indonesia
Authors: Arum Dian Pratiwi  , Febi Tri Oktaviani  , Nani Yuniar  , Lisnawaty
Published: April 2023

The restaurant is one of the places that was given a permit to continue to run its business activities in the midst of the Covid-19 pandemic. Restaurant employees can act as spreaders or contracting diseases, this can be through contact between food brought by employees and when interacting with visiting consumers. Therefore, it is important to implement health protocols as an effort to prevent the transmission of Covid-19. The general purpose of this study was to determine the factors related to compliance with the Covid-19 health protocol in restaurant employees, Mandonga District, Kendari City. This study was an analytical study with a cross sectional. The sample in this study amounted to 120 people who were taken using the technique of incidental sampling. Statistical test used test Chi-square with independent variables namely knowledge, education, belief, availability of infrastructure, and economic status with measuring tools in the form of questionnaire sheets and interview methods. The results showed that 106 respondents (88.3%) did not comply with the Covid-19 health protocol and 14 (11.7%) complied with the Covid-19 health protocol. Knowledge variable (p-value =0.000), education (p-value = 0.038), confidence (p-value =0.000), the availability of infrastructure (p-value =0.000) indicates that there was a relationship with Covid-19 health protocol compliance, while the economic status variable (p-value =0.196) showed that there was no relationship with Covid-19 health protocol compliance. The conclusion of the study showed that the variables of knowledge, education, belief, availability of infrastructure have a relationship with Covid-19 health protocol compliance, while the economic status variable has no relationship.
GVHD in its sclerodermiform form revealing type 1 diabetes: A case report
Authors: Hassan Aden Neima  , M’ Ballou Camara  , S. RAFI  , G. El MGHARI  , N. El ANSARI
Published: April 2023

Sclerodermiform syndrome is Common in diabetic, it encompasses a set of manifestations that preferentially affect the hands and back, but the association of type 1 diabetes with systemic sclerosis is a rare entity. We report the case of 18-year-old patient from a consanguineous marriage, with a history of acute myeloid leukemia which he was treated by an allograft in France associated with chemotherapy 9 session and immunosuppressants currently in complete remission, diabetic type 1 for 4 years, hypothyroidism under levothyrox 50ug / d. At the interrogation the patient reported the consequences of the graft were marked by stage I cutaneous GVHD confirmed by skin biopsy of which he received corticosteroid therapy at a dose of 10mg / day in addition to neoral or slightly atrophic hyperpigmented macules not sclerotic at the level of the back and the lateral surface of the left foot. The patient also had corticosteroid-induced complications, including diabetes and osteoporosis. On physical examination tendon retraction, elbows and finger, Amyotrophy of the hands, palpable thyroid not increased volume allowed for glycemic imbalance. At TSH biology = 6uui / ml, HBA1C = 8%, anti-GAD antibody negative to cervical ultrasound: thyroid hypotrophy with thyroid nodules classified EUTIRADS 2. The patient is referred for follow-up in dermatology. The association of sweet diabetes and sclerodermiform lesions is frequently linked to the glycemic imbalance responsible for an accumulation of extracellar matrix and excessive glycation of collagen. The search for signs of scleroderma should be evoked in front of a diabetic hand syndrome to Watch for and treat associated pathologies.
A Study on the Free Use of Public Works: Focused on the Seoul Central District Court’s 2019 Gadan 5207564 Decision
Authors:   Korea Copyright Commission, Yoo Ji-Hye
Published: April 2023

The Copyright Act has regulations on the free use of public works that guarantee the free use of public works by limiting the copyright of works produced with the government’s budget. According to the relevant regulations, the copyright of public works of the state or local governments is restricted, and the copyright of public works of public institutions under the Act on the Management of Public Institution is not restricted, but need to follow to government policies. As part of the policies, KOGL is being implemented to indicate the scope of free use and permission to use public works. Recently, a copyright infringement occurred due to an error in the application of KOGL. The case only dealt with whether the user infringed the copyright, but cases of misrepresenting the scope of the license due to a mistake of a public institution may continue to occur, and it could cause reliability problems for the actions of public institutions. On the other hand, the Act On Promotion Of The Provision And Use Of Public Data(‘Public Data Act’) regulates the provision and use of public data, which is a concept overlapping public works, and there is a concern about inconsistency with the free use system of public works under Copyright Act. In this background, this paper reviews the Seoul Central District Court's decision on April 9, 2021, compares and analyzes the free use of public works under the Copyright Act and the Public Data Act, and suggests implications and improvement.
Improvement of Database Rights for the Development of Data Economy
Authors:   Korea Copyright Commission, Lee Sang-Yong
Published: April 2023

In order to support the transition to a data economy where data functions as an important product and commodity, it is necessary to establish an institution to encourage producing and opening quality datasets. Database right under the Copyright Act and the prohibition of unauthorized use of other’s achievements and illegal use of data under the Unfair Competition Prevention Act serves as potential institution for protection of datasets. Each of these has its own strengths and weaknesses and can play a role, but the prospects of the database right stand out in particular. This is because it has excellent clarity and predictability, protects against infringement by non-competitors, and separates the domains of monopoly and sharing appropriately and clearly. However, database right is not without room for improvement. First, there are unstructured datasets without searchability among training data for AI, and it is necessary to remove the element of searchability from the concept of database in order to include them in the scope of protection. Second, in order to compensate for the uncertainty of protection requirements, it is necessary to introduce the provision for presuming the establishment of ‘substantial part’ of the database when structural information on the arrangement or composition of materials is included. Third, it is necessary to reexamine the boundary between monopoly and sharing. For example, if the database is the sole source for a certain data, it may be desirable to introduce a compulsory licensing regime according to the FRAND standard.
PENGEMBANGAN E-MODUL FISIKA BERKONTEKS ETHNOPHYSICS PADA POKOK BAHASAN GERAK MELINGKAR
Authors: Dani Rahma , Jufrida Jufrida , Basuki Fibrika Rahmat , Nurmaliza Nurmaliza
Published: April 2023

Penelitian ini bertujuan untuk mengembangkan e-modul fisika berkonteks ethnophysics pada pokok bahasan gerak melingkar. Penelitian ini menggunakan model pengembangan 4D (Define, Design, Develop, dan Dessiminate). Subjek penelitian ini adalah siswa kelas X SMAN 7 Kota Jambi dan SMAN 9 Kota Jambi dengan jumlah siswa sebanyak 30 orang. Instrumen yang digunakan dalam penelitian ini berupa lembar observasi, lembar wawancara, lembar validasi ahli materi dan media, serta angket persepsi siswa. Jenis data yang diperoleh yaitu data kualitatif dan data kuantitatif. Data kualitatif dianalisis  secara deskriptif dan dan data kuantitatif dianalisis menggunakan statistik deskriptif. Penelitian ini menghasilkan e-modul fisika berkonteks ethnophysics pada pokok bahasan gerak melingkar. Hasil validasi oleh ahli materi diperoleh persentase sebesar 95,93% dengan kategori sangat baik, ahli media sebesar 98,33% dengan kategori sangat baik, dan hasil persepsi siswa sebesar 88,9% dengan kategori sangat baik.
PENGARUH MODEL PEMBELAJRAN PROBLEM BASED LEARNING TERHADAP KETERAMPILAN BERPIKIR KRITIS DAN KEMAMPUAN PEMECAHAN MASALAH KELAS X DI SMA NEGERI 36 MUSI BANYUASIN
Authors: Sari Tri Novita , Sukarno Sukarno , Irawan Turino Adi
Published: April 2023

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Problem Based Learning (PBL) terhadap keterampilan berpikir kritis dan kemampuan pemecahan siswa kelas X di SMA Negeri 36 Musi Banyuasin. Penelitian ini merupakan penelitian kuantitatif menggunakan pendekatan Quasi Eksperiment dengan desain penelitian One Group Pretest-Posttest. Pengumpulan data dengan menggunakan lembar angket dan tes. Dalam penelitian ini terdapat sampel sebanyak 27 siswa dengan teknik pengambilan sampel yaitu Purposive Sampling. Berdasarkan data dan pembahasan ditemukan bahwa penggunaan model pembelajaran hasil analisis uji “t” diketahui nilai signifikasi model pembelajaran PBL adalah 0,81 > 0,05, berpengaruh terhadap keterampilan berpikir kritis. Sedangakan, pengaruh kemampuan pemecahan masalah terhadap keterampilan berpikir kritis nilai signifikansi adalah 0,22 > 0,05. Artinya terdapat pengaruh saat sebelum diberikan model pembelajaran dengan sesudah diberi model pembelajaran.
ANALISIS PROBLEMATIKA PROSES PEMBELAJARAN LISTRIK DINAMIS DAN SOLUSINYA DI SMA NEGERI 4 BATANGHARI
Authors: Kurnia Melisa Bella , Sukarno Sukarno , Syefrinando Boby
Published: April 2023

Penelitian ini bertujuan untuk mengetahui problematika dalam proses pembelajaran listrik dinamis dan solusinya. Penelitian ini dilaksanakan melalui metode kualitatif yang dilaksanakan di SMAN 4 Batanghari. Data proses pelaksanaan pembelajaran listrik dinamis diperoleh melalui lembar observasi guru dan peserta didik. Hasil penelitian menunjukkan: (1) Problematika proses pembelajaran listrik dinamis di SMAN 4 Batanghari terdapat beberapa aspek yang dilihat, diantaranya problematika dari peserta didik, problematika proses pelaksanaan pembelajaran di dalam kelas, problematika sarana dan prasasara. Untuk problematika proses pelaksanaan pembelajaran didalam kelas terdapat faktor yang mempengaruhinya, yaitu ketidakaktifan peserta didik, kurangnya waktu pada saat jam pelajaran. Untuk problematika sarana dan prasarana ditinjau dari tidak adanya alat-alat praktikum di dalam laboratorium fisika, terkhusus alat untuk materi listrik dinamis, sehingga peserta didik tidak bisa melakukan praktikum. (2) Solusi problematika proses pembelajaran listrik dinamis yaitu menggunakan Media pembelajaran bebasis digital dengan menggunakan aplikasi  phET. Dengan penggunakan media tersebut proses pembelajaran akan berjalan dengan baik, hal itu akan lebih mudah memahami materi dan konsep serta bisa melakukan simulasi praktikum, penggunaan media tersebut juga minim resiko apabila melakukan praktikum secara virtual.
Relationships between Vascular Leakage Factor and Pulmonary Dysfunction in Dengue Hemorrhagic Fever
Authors: Kustiyah Azizah Retno , Soemantri AG Soemantri AG
Published: April 2023

Background: Mortality in Dengue patients hospitalized in Dr. Kariadi Hospital, Semarang is very high. The most common cause of death were bleeding and Multiple Organ Dysfunction including pulmonary dysfunction that manifest as Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS). The previous study have shown the incidence of ARDS in DSS but the incidence of pulmonary dysfunction in dengue hemorrhagic fever is unknown.Design and Methods: An analytical observational study was performed in Non DSS and DSS patients. Researsh subjects were patients, aged 3-14 years old, with DHF according to WHO criteria 1999 hospitalized in the pediatric ward and Pediatric Intensive Care Unit (PICU) Dr. Kariadi Hospital Semarang from February 2003 until August 2005.Result: Forty patients were included for analysis consisting of 20 Non DSS and 20 DSS. Mann-Whitney analysis showed a significant differences in the incidence pulmonary dysfunction between Non DSS and DSS patient (p < 0,05). Kendallâ€™s Tau_b analysis showed a relationship between PEI value and pulmonary dysfunction, the low total protein plasma level with pulmonary dysfunction and the low albumin plasma level with pulmonary dysfunction with r = 0.552; 0.540; 0.353 respectively, (p= 0.01).Conclusion: The study showed that pulmonary dysfunction occured more frequent in DSS than Non DSS. There were relationships between vascular leakage factors (PEI, total protein level, albumin level) with incidence of pulmonary dysfunction in DHF patients (Sains Medika, 3(1):1-15).
The Correlation between the Dimention of Trust among the Member of the Group and the Effectiveness of PBL Tutorial Group
Authors: Istadi Yani
Published: April 2023

Background: The tutorial plays a central role in problem-based learning (PBL). The effective implementation of small group tutorials is one of the key contributors to the students success in examinations. This study aimed to identify factors perceived as the predictors for effectiveness of PBL group tutorial.Design and method: The subjects of the study were all of the students (year of 2008) of the Medical College of Sultan Agung Islamic University taking the Tropical Disease Module. The adapted version of the scales adopted in this study included the scale developed by Van den Bossche et al for assessing team (group) effectiveness, trust dimension and learning behavior, a scale developed by Dolmans & Ginns (2005) for assessing tutorâ€™s performance, a 5 points likert scale was used to asses the student opinions. Quantitative approach with correlation and multiple regression analysis was applied.Result: Of 238 students included in the study 84 (37.3%) were male and 139 (62.3%) were female. There was a significantly positive correlation between the trust dimension related to the interpersonal relationship among the members of tutorial group with the effectiveness of tutorial group ( r = 0.631, p< 0.01). There was a medium correlation among cohesion, group potency and psychological (r= 0,700, p < 0.05 there was correlation among the variables of (r = 0,557, p < 0,001), group potency (r = 0,517, p < 0,001), and psychological assurance (r = 0,437, p < 0.001). These three variables contributed to the group effectiveness as much as 48.4% with a F value of 87.857. The component of independence was not found to be the predictive factors for group effectiveness. The correlations among the variables of cohesion, group potency and psychological assurance resulted in contingency coeficien of 0.700 with p<0.05.Conclusion: The higher trust related to the interpersonal relationship among the member of groups, the more effective the group will be. Cohesion, group potency and psychological assurance were found to be the predictive factors for group effectiveness (Sains Medika, 3(1):16-23).
Hyperexpression of TNF-Stimulated 6 (TSG-6) of HumanTracheal Aspirate and Bronchial Alveolar Lavage from Heavy-Smoker and Lung TB
Authors: Trihadi Djoko
Published: April 2023

Background: TSG-6, an inflamation-associated protein, forms covalent complexes with heavy-chains from TNF. These protein potentiating the antiplasmin activity of this serine protease inhibitor. The aim of study was to determine and show that TSG-6 are present in Bronchoalveolar Lavage (BAL) from patients with lung TB and heavy smoker.Design and Methods: Experiments conducted in vitro with purified components revealed that TSG-6 had immunodetection in the Human Tracheal Aspirates (HTA) and BAL of heavy smoker and Lung Tuberculosis.Results: Immunoprecipitation revealed that TSG-6 accounts in airways hyperresponsiveness for significant proportion of BAL and HTA, but not in control (p < 0,01). TSG-6 relevant protease inhibitor in airway secretion. In primary cultures of differentiated human airway epithelial, which suggest that TSG-6 may be induced by TNF. Our results suggest that TSG-6 may play an important protective role in bronchial epithellium buy increasing the antiprotese screen on the airway lumen. The present study identifies a novel function of TSG-6 by a distinct mechanism system regulated, enhancement of anti TK activity, and provides a rational for this activity within the context of inflamed airways. These findings correlate with the observed increases in protein expressions in human HTA and BAL.Conclusions: TSG-6 are hyper-expressed in airway epithelial cells in cultures of smoker and lung TB. The interactions of TSG-6 with other molecules are also potentially important to the pathophysiologic aspects of inflammatory airways diseases that remain to be elucidated (Sains Medika, 3(1):31-40).
The Effect of Honey Administration on Gastrohistopathological Image Study In Male White Wistar Rat Induced With Indomethacin
Authors: Suprijono Agus , Trisnadi Setyo , Negara Henri Perwira
Published: April 2023

Background: Gastric disorder often generates clinical symptoms such as gastritis or peptic ulcer. Bee honey has high nutrient has been shown to have a protective effect against drugs destroying stomach. The purpose of this study was the difference effect of honey in various concentrations on the gastrohistopathological image in male white Wistar rat induced with indomethacin. Design and Methods: This was an experimental research using control group post test design. 24 male white rats Wistar were randomly divided into 6 groups of 4 mice each. Group I served as the control group (standar and aquades), group II: 3.78 mg of indometachin, group III: 3.78 indomethacin and 3.6 ml honey (25%,) group IV: 3.78 indomethacin 3.6 ml honey (50%,) group V: 3.78 mg indomethacin 3.78 mg and 3.6 ml (75%(), group VI: 3.78 indomethacin 3,78 mg and honey 3.6 ml 100%. Treatment given by sonde once a day for 15 days. the gastrohistopathological image was evaluated for degree of gastritis and degree of peptic ulcer. The data were tested with test Kruskal-Wallis followed by Mann-Whitney test. Results: Kruskal-Wallis test showed at least significant differences in the degree of gastritis and peptic ulcer between between the two groups (p <0.05). Mann-Whitney test howed that not all groups compared to control showed a significant different in the degrees of gastritis and peptic ulcer. Conclusion: The study suggested that honey have effect on the gastrohistopathological image of indomethacin-induced stomach (Sains Medika, 3(1):41-47).
The Trial on the Effectiveness of Honey on White Rats Using Geliate Acetate Method An Experimental Study in Male Wistar Rat
Authors: Goenarwo Edijanti , Chodidjah Chodidjah , Susanto Heri
Published: April 2023

Background: Pain is the most common complaint of a disease that can be reduced using the analgesic drugs. Besides the pharmacological medication, the traditional medications are available including honey containing flavanoid. The compound can protect the lipid membrane from the damage and inhibit cyclooxygenase, the main path of the synthesis mediator for pain like prostaglandin. This study aims at finding out the efficacy of analgesic of honey using geliate asetate method.Design and methods: In an experimental study using post test only control group design, 25 Wistar rat (80-90 days, BW 180-220 gr) were randomly divided into 3 groups of 5 mice each. Gp1: =aquadest (negative control), Gp2: 0.675 g/BW honey, Gp3: 1.35g honey Gr 4: 2.7 g/kgBW honey and Gr 5 (possitive control): 4.5 mg/ BW of paracetamol. 5 minutes after the treatment, an intraperitoneal injection of acetic acid was given for all groups. Anova followed by post Hoc test was used for data analysis.Result: The honey concentration of 50% (1.35) g was found to have increasing effect of analgesic while the concentration of 25% and 100 % showed a reducing analgesic effect.Conclusion: Honey has been shown to have an analgesic effect in mice with the effective concentration of 50% (1.35 g/kgBW) (Sains Medika, 3(1):48-53).
The Difference in Effectiveness of 70% and 0.5% Chlorine to ReduceThe Germ Number on Stethoscopeâ€™s Membrane Experimental research at stethoscope in Baitul Izah Ward of Sultan Agung Islamic Hospital Semarang
Authors: Pramita Heny , Saugi Abduh Saugi Abduh , Chodidjah Chodidjah
Published: April 2023

Background: Recently, nosocomial infection (hospital- acquired infections) is estimated to affects more than 1.4 million of in patients in all over the world. Stethoscope is one source of nosocomial infection caused by the continuous contact from one patient to another. 70% alcohol and 0.5% chlorine can be used for disinfection. The purpose of the research is to find out the difference in the effectiveness of 70% alcohol and 0.5% chlorine to reduce the amount of germ on the stethoscopeâ€™s membrane.Design and Methods: This was an experimental research with the Post Test Only Control Group Design using 18 stethoscopes divided into 3 groups randomly. Group A was the control group (aquabidest), group B were treated with 70% alcohol treatment, and group C was treated with 0.5% chlorine. The research samples were the stethoscopes used to treat patient in Baitul Izah ward of Islamic Hospital of Sultan Agung Semarang. The data on the germ amount was analyzed using Kruskal-Wallis test. Results: There was a significant difference between aquabidest group and 70% alcohol group (p<0.05) and between aquabidest control group and chlorine group(p>0.05), nevertheless, there was no significant difference between the 70% alcohol group and 0.5% chlorine group ( 0.652). Conclusion: There was no difference in the effectiveness between 70% alcohol and 0.5% chlorine to reduce the number of germ on the stethoscopeâ€™s membrane (Sains Medika, 3(1):63-68).
The Length of Stay Difference between Under 5 Years Patient with Acute Diarrhoea Treated With and Without Probiotic An Analytical Study in RSUD Kota Semarang during the Period January to December 2007
Authors: F. Riandari F. Riandari , Priyantini M. Sri
Published: April 2023

Background: Diarrhoea is still public health problem and often cause outbreak with various morbidity and mortality. The long onset of acute diarrhoea causes the length of stay that affect the cost. So proper management is needed to shorten inpatient length of stay. Probiotic can make the convalescence of children with acute diarrhoea faster. The aim of the study is to know the lenght of stay difference between underfive year old children with acute diarrhoea treated with and without probiotic.Design and Methods: The study was an analitical study with case control design. Study Sample were all inpatient 6-24 month old children with acute diarrhoea in Kota semarang Hospital since January â€“ December 2007. Data were obtained from medical record in pediatric unit. Data analysis with stastitical test of Mann Whitney.Results: Of 130 samples, the lenght of stay average of < 5 years old children with acute diarrhoea with probiotik was 3,42 days compare 4,03 days children acute diarrhoea without probiotik. It is concluded that there was a significantly difference between two groups acute diarrhoea with probiotik and without probiotik.Conclusion: There was a significant difference between the length of stay for the patients with acute diarrhea with and without probiotic treatment. Mean of the length of stay for under 5 years old baby with and without probiotic were 3.42 days and 4.03 days respectively (Sains Medika, 3(1):78-83).
Effect of Jinten Hitam Seeds Oil (Nigella sativa L.) In adenocarsinoma Mammae C3H Mice In Vivo An Experimental Study on C3H Mice Inoculated With Cancerous Tissue
Authors: Suprijono Agus , Sumarno Sumarno , Hanugalih Hanugalih
Published: April 2023

Background: Jinten hitam (Nigella sativa L.) oil is a liquid made from Jintem hitam seeds which has been known to contain Thymoquinone having anti-cancer efect. Many cancer patients turn to cheaper alternative therapy including the traditional therapy. The objective of this experimental was to evaluate anti-cancer effect of Jinten hitam seeds oil in adenocarsinoma mammae C3H mice.Design and Methods: In this xperimental research with pre post test randomized control group design for 21 days, 24 C3H mice with tumor were divided into 4 group. K-I serves as a control given standard diet and aquades, K-II given standard diet, aquades and first dose of Jinten Hitam oil (0.1 ml/days), K-III given standard diet, aquades and second dose of Jinten Hitam oil ( 0.2 ml/days) and K-IV given standard diet, aquades and third dose of Jinten Hitam oil ( 0.3 ml/days). The volume was recorded at the day 21.Results: mean of the effect of Jinten hitam oil effect in adenocarcinoma mammae for the four group were 158.83 mmÂ³, 259.73 mmÂ³, 191.13 mmÂ³, K-IV 126.27 mmÂ³ respectively. Pair t-test and Wilcoxon test showed significant difference between First dose pre-First dose post and Second dose pre-second dose-post (p<0.05) and Anova test showed no significant difference between K-I K-II, K-I K-III, K-I K-IV, K-II K-III, K-II K-IV, K-III K-IV (p>0.05).Conclusion: Jinten Hitam oil has effect on the volume of Adenocarcinoma mammae in C3H mice (Sains Medika, 3(2):129-134).
Students Perceptions on the quality of clinical supervision among the 12 affiliated hospital of Medical Faculty of UNISSULA
Authors: Rahmawatie Dian Apriliana , Rahayu Gandes Retno , Prihatiningsih Titi Savitri
Published: April 2023

Background: Clinical supervision has a vital role in the learning process of undergraduate medical education because it may improve the studentâ€™s clinical performance of the students. Supervision is a complex activity and covers wide variety of applications. Medical faculty of Islamic Sultan Agung University has 15 affiliated hospitals for its clinical education. To assure the quality of the clinical program, an evaluation on the quality of clinical program is required. This study was conducted to assess the effectiveness of the clinical supervision among the 12 affiliated hospitals.Design and Methods: This study involved 181 students of clinical internship of the year 2003, 2004 and 2005 of medical faculty of Islamic Sultan Agung University having the clinical rotation at the stage of surgery, obsgyn, pediatrics, internal medicine, ENT, neurology, dermatology and venerology, psychiatry, across the affiliated hospitals. The subject were divided into groups based on the hospital they were placed. Clinical Teaching Effectiveness Instrument (CTEI) adapted in bahasa Indonesia was used. The Descriptive and Kruskal-Wallis test were applied for the data analysis.Results: Means of the effectiveness of clinical supervision for 12 affiliated hospitals ranged from 3.25 to 4.02. Kruskal-Wallis test resulted in the value of Chi-S=13.32 and p=0.27.Conclusion: Over all the clinical supervision for the 12 affiliated hospitals is perceived good and shows no significant difference. However the practice of clinical supervision varies among the hospitals (Sains Medika, 3(2):135-149).
Prevalence of Influenza Viruses (Influenza Like Illness) In Regional Laboratory Avian Influenza Semarang
Authors: Wahyutomo Ridha , Ciptaningtyas V. Rizke , Hadi Purnomo
Published: April 2023

Background: Influenza is the major health threat worldwide causing illness and death every year. However, data on the epidemiology of influenza in tropical countries, including Indonesia, are still limited. Up dated data for its prevalence is needed to monitor its spreading and to evaluate its outbreak. Therefore a working regional laboratory in surveillance of ILI (Influenza Like Illness) was formed. This research was conducted to provide updated data on prevalence of ILI in regional laboratorium avian influenza Semarang.Design and Method: Data from patients examined in the regional laboratory of avian influenza Semarang from April 2009 until December 2010 was collected. Samples were obtained from Malang sentinel, Yogyakarta sentinel and Semarang sentinel. Samples were examined using PCR to detect influenza A, influenza B, and swine flu.Result: out 1367 patients tested, 279 patients (20.41%) were from Yogyakarta sentinel, 619 patients (45.28%) were from Malang sentinel, and 467 patients (34.16%) were from Semarang sentinel. Flu A virus was detected in 117 patients (8.5%). Influenza B virus was found in 39 patients (2.8%). H1 virus was detected in 5 patients (0.36%). H3 virus was detected in 45 patients (3.29%). Swine flu virus was detected in 3 patients in Malang.Conclusion: The highest prevalence of flu A and flu B examined in avian influenza regional laboratory Semarang was from Semarang sentinel, followed by Yogyakarta sentinel and Malang (Sains Medika, 3(2):157-161).
The Difference in The Effect Between The Oxygenated and Mineral Water on The O2 Saturation And Urine pH
Authors: Ellyana Naila Shulya , Sarosa Hadi , Hussaana Atina
Published: April 2023

Background: During exercise, oxygen decreases due to acidosis leading the production acid urine by kidney. Oxygenated water having capability to absorb more oxygen compared to mineral water is used to meet the oxygen need during exercise. This study investigated the effect of oxygenated water and mineral water on the O2 saturation and urine pH.Design and method: In this crossover study, 46 subjects were randomly assigned to either oxygenated water or mineral water for 24 hours followed by a crossover to the other regimen for an additional 24 hours of treatment. After 100 m sprint running for 20 minutes, the oxygen saturation and urine pH of the subjects were assessed.Result:The mean oxygen saturation before and after the treatment of oxygenated water were 96.78Â±1.32 and 97.61Â±0.93 respectively. The mean oxygen saturation before and after the mineral water treatment was 97.35Â±0.85 and 97.01Â±1.04 respectively. The urine pH after the administration of oxygenated water and mineral water were 6.643Â±0.69 and 6.585Â±0,58 respectively. Wilcoxon test resulted in no significant difference in pH after the treatment of oxygenated water and mineral water (p=0.498). Urine pH after the treatment of oxygenated water was found to be higher compared to that of mineral water.Conclusion: the oxygenated water increases the O2 saturation and urine pH compared to mineral water (Sains Medika, 3(2):162-167).
Low Birth Weight as The Risk factor of Coronary Heart Diseases
Authors: Wibowo Joko Wahyu
Published: April 2023

Low birth weight, a nutritional deficiency is related to the increased in the coronary heart disease insidence. Low birth weight is correlated with the hipotalamus-pituitary-adrenal responsible for the the concentration of cortisol in sirculation, increased in homosistein, insuline resistence and increased C reactive protein playing role on the aterosclerosis process predispose the corronary disease. This paper will discuss the relationship between the low birth weight and the ateroclesoris process leading to coronary heart disesase (Sains Medika, 3(2):185-200).
Problem Based Learning (PBL) in Competence Based Curriculum and The Accademic Achievement: Evaluation of PBL Implementation
Authors: Kusumawati Wiwik
Published: April 2023

Background: Medical Faculties in Indonesia has implemented problem based learning (PBL) in competence based curriculum as a learning strategy. The aim of this study is to know the effect of PBL method on academic achievement and factors affecting successfull PBL implementation.Design and Method: This study used quantitative and qualitative method. Data collection method is by distributing questionnaires, focus group discussion (FGD) and document analysis of studentsâ€™ academic achievement. This study included 3 year level students (2004, 2005, 2006) using PBL in school of medicine faculty of medicine and health sciences UMY (FMHS UMY).Result: GPA average > 2.5 is 32.47 %, MCQ > 60 is 33.1% and OSCE is 92.8%. The role of tutor and also practical instructor to facilitate learning objective was not optimal. The factors for the poor implementation of PBL includes curriculum planning (understanding of PBL concept and dissemination of curriculum), implementation of curriculum (various of block load, opportunity for self directed learning, e-learning effectivity, etc) and assessment system (the number of students who reach minimal standar of MCQ is low, validity of MCQ is also low, etc).Conclusion: This study suggest the need to improve planning, implementation and curriculum assessment to support implementation of PBL. The role of Lecturer, tutor and practical instructor should be improved through faculty development to faciliate teaching learning proccess in PBL method (Sains Medika, 4(1):30-38).
The Study of Mouth Washing Duration with Boiled Uncaria gambir on the Dental Plague Formation
Authors: Susilowati Aning , Sumarawati Titiek
Published: April 2023

Background: Dental plague has been known to be the major agent causing dental carries and periodontal disease which are the most common dental and soft tissue diseases with the prevalence of 70-80%. The preventive measure including the use of chemical substance of catechin having anti-plague activity in the form of mouth wash has been shown to have effects on the dental plague formation. The objective of this study was to find out the duration of mouth washing with boiled gambir (Uncaria ambir) on the plague formation in Pondok Pesantren Al-Badriyah Mranggen, Demak.Design and Method: In this study using Pretest-Posttest Control Group Design, 44 samples of subjects was divided into 4 groups of 11 each. Group I, II, II were treated with the mouth wash of Uncaria gambir boiled 2, 3, 4 minutes respectively. Group IV serving as control was treated with mouth wash of water for 3 minutes. The data was analyzed with non parametric test using Kruskal-Wallis followed by Mann-Whitney test with p < 0.05.Result: Kruskal Wallis analysis showed a significant difference in mean of plague before and after the treatment among the four groups (p < 0.05). Mann-Whitney test showed no significant difference between group I and III ( p> 0.05) and significant difference for the rest of the groups (p < 0.05). Conclusion: The mouth rinse duration using boiled Gambir has been shown to have an effect on the dental plague formation. 3 minute mouth washing shows the optimum effect (Sains Medika, 4(1):57-62).