bluuebunny/crossref_metadata_2025 huggingface dataset:
Possibilities of targeting in food chain safety risk communication
Authors: Süth M. , Mikulka P. , Izsó T. , Kasza GY.
Published: October 2018

In recent years, there have been many changes in the food market, which have greatly transformed our approach to food chain supervision. The increasing complexity of the food chain (e.g. globalization of food trade, expansion of raw materials and additives, technical advancement), the frequent changes in food consumption trends and the phenomenon of food crime belong to the most challenging issues for food chain control institutions. These factors require the re-evaluation of the role of consumers in the food chain. The overall aim of this research was to explore consumers’ risk perception and risk avoidance for a more efficient, targeted risk communication. In the survey 1003, face-to-face interviews were made using questionnaire. The statistical analysis of data was followed by the identification and characterization of 4 relevant target groups with cluster analysis method: disinterested youngsters (17.0%), conscious elders (39.4%), food adepts (27.5%), and soul of the family (16.1%). Results indicated, that the Hungarian society can be segmented regarding to food associated risk perception and avoidance. It has been also proven, that risk perception is influenced by demographic factors. Furthermore, we have also managed to conclude that efficient risk communication would require a well-aimed and focused communication strategy.
An artistic, mythological and documentary study of the Atargatis panel from et-Tannur, Jordan
Authors: Almasri Eyad , Balaawi Fadi , Alshawabkeh Yahya
Published: October 2018

In 1937 and 1938, a group of high-relief and round statues were uncovered during the joint expedition of the American School of Oriental Research in Jerusalem and the Department of Antiquities in Palestine at the Khirbet et-Tannur Temple, located in Jordan. This expedition was headed by Nelson Glueck (Figs 1, 2). The statues uncovered are important in that they offer considerable information about Nabataean art and religion. This paper concentrates on one of the high-relief statues, called the Atargatis Panel by its excavator, Glueck. It was chosen as a case study for its availability in Amman, Jordan. The other Atargatis statues found at the site are now in the Cincinnati Art Museum in the United States of America. This paper also examines the Nabataean religious beliefs concerning Atargatis and her fertility cult, in addition to the art style of the statue. Furthermore, the digital 3D imaging documentation of the Atargatis statue at The Jordan Museum is presented. Dense image matching algorithms presented a flexible, cost-effective approach for this important work. These images not only provide geometric information but also show the surface textures of the depicted objects. This is especially important for the production of virtual 3D models used as a tool for documentary, educational and promotional purposes.
The Parthian rival and Rome’s failure in the East: Roman propaganda and the stain of Crassus
Authors: Overtoom Nikolaus Leo
Published: October 2018

The consequences of Crassus’ invasion of Mesopotamia in 54–53 BCE were unanticipated and unintended; however, his disastrous failure shocked the Roman world and suddenly established the Parthians as a serious rival to Rome. Moreover, the shame the Romans felt after the Battle of Carrhae was considerable. The battle scarred the Roman psyche and severely damaged the Roman ego. This study synthesizes and investigates what became a vicious and virulent Roman literary tradition of anti-Crassus propaganda, examining how numerous Roman writers over the course of numerous centuries used the dead and disgraced Crassus as a convenient scapegoat to help explain Rome’s failure to dominate the East and subdue the Parthian rival. It demonstrates that these writers ignored the legitimate causes for the First Romano-Parthian War (56 BCE – 1 CE), which Crassus had inherited, and illustrates that the disaster at Carrhae became a popular moralizing lesson about the consequences of greed, impiety, and hubris.
‚Libri e biblioteche nell’epistola I. 20 di Orazio*
Authors: Acél Zsolt
Published: October 2018

This study attempts to give an interpretation of Horace’s final piece of his First Book of Epistles from the point of view of the ancient culture of books and literature. Horace’s Epistles expressly mention the Library of Palatine Apollo. From a distance, they refer to some of the principles of Augustan cultural politics which created the library itself, and also draw an accurate picture of the process of the auto-canonization process which created the (concept of the) golden age of Roman literature. First, the study outlines the basic characteristics of the Horatian epistle, then looks for answers to the following questions: what are the forms of literary publicity and how do libraries appear in the Epistles? What does the need for canonization mean? How is it possible to canonize the living? How does the concept of the golden age of Roman literature take shape in the literature around 10 BCE?
19. századi épületek értékvédelme Győr-Moson-Sopron megyében
Authors: Veöreös András
Published: October 2018

A 19. századi védett épületek aránya nagy valószínűséggel elmarad a teljes történeti épületállományon belül az ebből az időszakból származó épületek arányától. Elgondolkodtató ez amiatt, hogy a műemléki védelmet nem élvező klasszicista és romantikus, de még inkább a századvégi historizáló és szecessziós építészeti emlékeink jelentős része rendelkezik az eredeti (védhető/védendő) épületalkatrészekkel. Ezzel szemben a szinte kivétel nélkül védettség alatt álló középkori vagy barokk kori épületeinken a fő tartószerkezet kivételével alig találunk eredeti, építéskori épületalkatrészeket. Így tetőszerkezetek, tetőfedések, padlásszellőzők, padló- és falburkolatok, ajtók, ablakok, kapuk, kilincsek, rácsok, lépcsőkorlátok, vakolatok, díszítőfestés, stukkó, cserépkályhák nyújtanak képet a korszak építési technikájának rendkívül magas színvonaláról. A műemléki értékek pusztulása alapvetően három okra vezethető vissza: műszaki, erkölcsi és bürokratikus avulásra. Az elavult szerkezetek esetében válik szükségessé a valamilyen szintű felújítás, ami sok esetben szintén az eredeti épületelemek károsodásához vezet. Jelen cikk néhány jellemző példa bemutatásával próbál meg képet adni a 19. századi, műemléki értékkel bíró épületek megőrzése körüli dilemmákról.
Egy továbbépítés rétegei
Authors: Pazár Béla
Published: October 2018

A technika termékeit egyre gyorsabban fogyasztjuk és dobjuk el. Csak a legújabbak érdekelnek, a többi formátlanná vált hulladék, szemét, amivel egyre inkább kezdenünk kell valamit. Az épületek évtizedekig, évszázadokig néha évezredeken át velünk vannak, újdonság értékük tehát eleve viszonylagos, nem emelhető más értékeik fölé, azokkal nem állítható szembe. Ez a felismerés a szűkebb értelemben vett technika bűvöletében élt 20. század elmúltával arra indít, hogy újraértelmezzük az új és a régi, és ezzel együtt a stílus és a mű értelmét, kapcsolatát, és felülvizsgáljuk a stílusok koncepciójába kimerevített múltképünket az építészetben is. Az ezredforduló után több jelentős értékű régi épület újra felépítése, újra befejezése Európában ezt a változást jelzi.
Development of magnetic solid-phase extraction coupled with dispersive liquid–liquid microextraction method for the simultaneous determination of biphenyl and biphenyl oxide in water samples
Authors: Noori Arezoo Hassan , Rezaee Mohammad , Kazemipour Maryam , Mashayekhi Hossein Ali
Published: October 2018

A new and sensitive method, termed magnetic solid phase extraction combined with dispersive liquid–liquid microextracton (MSPE–DLLME), has been developed for the simultaneous determination of biphenyl and biphenyl oxide in water samples. Different parameters influencing the extraction efficiency, including the amount of sorbent, sorption time, type of elution solvent and its volume, type of extraction solvent and its volume, and elution time were optimized. The calibration curves were linear in the range of 0.5–100 μg/L for both of them. The limits of detection (LODs) were achieved, 0.03 μg/L for biphenyl and 0.07 μg/L for biphenyl oxide, respectively. Ultimately, the applicability of the method was successfully confirmed by the extraction and determination of biphenyl and biphenyl oxide in sea, river, tap, and water well.
An update of the incidence of fulminant hepatitis due to viral agents during pregnancy
Authors: Seifoleslami Mehri
Published: October 2018

Fulminant hepatitis in pregnant women is one of the major public health issues and remains a challenging clinical problem with extremely high maternal and fetal morbidity and mortality, which, in parallel, viral factors are the most common cause of hepatic disorders and dysfunction during pregnancy that may lead to fulminant hepatic with a fast progression. Therefore, this review helps to inform clinicians about the current status of the incidence of fulminant hepatitis due to viral agents during pregnancy.
Spanish validation of the Sexual Addiction Screening Test
Authors: Castro-Calvo Jesús , Ballester-Arnal Rafael , Billieux Joel , Gil-Juliá Beatriz , Gil-Llario María Dolores
Published: October 2018

Background and aims

Sexual addiction is a pathological behavior characterized by a combination of excessive sexual desire and impaired ability to control it. Its incidence ranges between 1.2% and 32.2%, although this number may vary depending on the screening tool used. This wide variability is largely due to the use of non-validated instruments (e.g., structural validity relying on exploratory analyses, instruments translated without an additional validation process, or instruments validated in another format). To deal with these limitations, this study tested the psychometric properties of the Spanish paper-and-pencil and online versions of the Sexual Addiction Screening Test (SAST).

Methods

A total of 2,528 participants (1,163 males) completed the Spanish version of the SAST, along with other instruments assessing sexual compulsivity (1,585 = paper-and-pencil, 943 = online).

Results

The exploratory factor analysis yielded a four-factor structure explaining 57.39% of the variance for the SAST paper-and-pencil version. This factor structure was then verified for the online version through the use of confirmatory factor analysis [χ2(264) = 441.59; χ2/df = 1.66; RMSEA = 0.02; CFI = 0.94; IFI = 0.94]. This methodology was also used to support measurement invariance (configural, metric, and scalar invariance) according to gender. The reliability of the total score ranged from .82 to .85. Similarly, correlations with related scales were positive and significant (r between .22 and .71). Temporal stability 1 year after the first application was 0.65 (paper-and-pencil format) and 0.60 (online version).

Conclusion

These results, together with the absence of questionnaires translated into Spanish to assess this construct, justify the use of the SAST in the evaluation of sexual addiction in Spanish-speaking countries.
Relationship between attention-deficit hyperactivity disorder symptoms and problem gambling: A mediation analysis of influential factors among 7,403 individuals from the UK
Authors: Jacob Louis , Haro Josep Maria , Koyanagi Ai
Published: October 2018

Background and aims

Our goal was to examine the association between attention-deficit hyperactivity disorder (ADHD) symptoms and gambling problems, and to identify potential mediating factors of this association.

Methods

This study used cross-sectional, community-based data from 7,403 people aged ≥16 years who participated in the Adult Psychiatric Morbidity Survey 2007. ADHD symptoms were assessed using the Adult ADHD Self-Report Scale (ASRS) Screener. Problem gambling was assessed using a questionnaire based on the 10 DSM-IV diagnostic criteria for pathological gambling. Respondents were classified as having no problem, at-risk, or problem gambling. Logistic regression and mediation analyses were conducted to analyze the association between ADHD symptoms (i.e., ASRS score ≥14) and problem gambling and the role of several variables in this association.

Results

The prevalence of at-risk (5.3% vs. 2.4%) and problem gambling (2.4% vs. 0.6%) was higher in individuals with ADHD symptoms than in those without ADHD symptoms. ADHD symptoms were significantly associated with both at-risk (OR = 2.15; 95% CI = 1.22–3.79) and problem gambling (OR = 3.57; 95% CI = 1.53–8.31) when adjusted for age, sex, and ethnicity. Common mental disorders (CMDs; i.e., depression and anxiety disorders) (mediated percentage = 22.4%), borderline personality disorder (BPD) traits (22.1%), stressful life events (13.2%), stress at work or home (12.6%), alcohol dependence (11.8%), and impulsivity (11.2%) were significant mediators in the ADHD–gambling association.

Discussion and conclusions

Overall, ADHD symptoms were positively associated with problem gambling. CMDs, BPD traits, and stressful life events were important mediators in this relationship.
The association of celebrity worship with problematic Internet use, maladaptive daydreaming, and desire for fame
Authors: Zsila Ágnes , McCutcheon Lynn E. , Demetrovics Zsolt
Published: October 2018

Background and aims

Celebrity worship, defined as an obsessive fascination with a famous person, has been associated with several mental health problems, such as symptoms of depression and anxiety, dissociation, and body image concerns. The aim of this study was to extend the scope of investigation of previous research on psychological correlates by exploring the association of celebrity worship with compulsive behaviors, such as problematic Internet use, maladaptive daydreaming, desire for fame, and self-efficacy.

Methods

A voluntary sample of 437 Hungarian adolescents and adults (78.3% male; Mage = 24.7 years, SD = 7.4) completed an online questionnaire focusing on attitudes toward celebrities and other relevant variables.

Results

As a result of hierarchical regression analyses, high levels of celebrity worship were associated with problematic Internet use, maladaptive daydreaming, and desire for fame. Furthermore, females were at higher risk to become obsessed with celebrities than males.

Discussion and conclusion

These findings provide with a more comprehensive picture of psychological difficulties associated with celebrity worship and may contribute to a better understanding of this phenomenon.
The relationship between sexual sensation seeking and problematic Internet pornography use: A moderated mediation model examining roles of online sexual activities and the third-person effect
Authors: Chen Lijun , Yang Ying , Su Wenliang , Zheng Lijun , Ding Cody , Potenza Marc N.
Published: October 2018

Background and aims

Internet pornography consumption is prevalent among college students and problematic for some, yet little is known regarding the psychological constructs underlying problematic Internet pornography use (PIPU). Drawing on the Interaction of Person-Affect-Cognition-Execution model, this study tested a model that sexual sensation seeking (SSS) would impact PIPU through online sexual activities (OSAs) and that this relationship would be influenced by the third-person effect (TPE; a social cognitive bias relating to perceived impacts on others as compared to oneself) in a gender-sensitive manner.

Methods

A total of 808 Chinese college students (age range: 17–22 years, 57.7% male) were recruited and surveyed.

Results

Men scored higher than women on OSAs and PIPU and on each scale’s component factors. The relationship between SSS and PIPU was mediated by OSAs, and the TPE moderated this relationship: the predictive path (SSS to PIPU) was significant only in participants with high TPE. The moderated mediation model was not invariant across gender groups, with data suggesting that it accounted for a greater proportion of the variance in men as compared with women.

Discussion and conclusions

The findings suggest that SSS may operate through participation in OSAs to lead to PIPU, and this relationship is particularly relevant for college-aged males scoring high on the TPE. These findings have implications for individuals who might be particularly vulnerable to developing PIPU and for guiding educational efforts and targeting interventions in college-aged students. The extent to which these findings extend to other age groups and cultures warrants further examination.
Pathological buying symptoms are associated with distortions in judging elapsed time
Authors: Nicolai Jennifer , Moshagen Morten
Published: October 2018

Background and aims

Pathological buying (PB) is often assumed to be related to deficits in impulse control. Distortions in judging elapsed time are one component of behavioral impulsivity. This study was set out to examine the hypothesis that PB propensity is associated with distorted time perception, such that time is perceived to pass more slowly.

Methods

The study is based on a convenience sample of 78 adults. Symptom severity of PB and related problems/disorders (substance use, borderline, depression, mania, and obsessive–compulsive disorder) as well as four dimensions of trait impulsivity were assessed. A time-production task was employed that required participants to produce prespecified time intervals ranging from 1 to 60 s.

Results

PB propensity was associated with the belief that time elapses more slowly, even when controlling for symptoms of related disorders and general trait impulsivity. Neither trait impulsivity nor symptoms of related disorders were predictive of distortions in judging elapsed time.

Discussion and conclusion

These results suggest that PB propensity is related with non-specific, general deficits in judging elapsed time as a specific component of behavioral impulsivity.
Classification of problematic Internet usage types by motives and contexts with elementary and secondary school-aged counseling clients
Authors: Kim Bugeun , Lee Seul , Doh Young Yim , Gweon Gahgene
Published: October 2018

Background and aims

Past research on the classification of problematic Internet use (PIU) has focused on symptom-based severity and usage motive in order to understand its mechanism. Recently, usage context, such as family or social relationships, has been identified as a key influencing factor of PIU. Therefore, we extended the classification of PIU to include usage context in addition to symptom-based severity and usage motive.

Methods

To classify PIU types, we conducted two studies. First, we performed a clustering analysis, where 265 counseling cases were clustered into usage types in terms of motive and context. After characterizing each usage type, we examined their hierarchical relationships by considering symptoms. Second, we performed a focus group interview with six counselors to increase the transferability of usage types. This transferability was established by matching counselors’ quotations to the usage types. When usage types showed consistency between quotations and the clustering analysis, we identified the progression patterns between hierarchical relationships.

Results

The clustering analysis of motive and context yielded six usage types with three hierarchical relationships. The focus group interview results verified the transferability of these six types and identified two progression patterns between the hierarchical relationships.

Discussion and conclusion

Although usage motive and context were given equal weight before the clustering analysis, the resulting types revealed that usage context played a greater role in the classification process.
Symbolic and realistic threats – frame analysis of political and media discourses about refugees and migrants
Authors: Egres Dorottya
Published: October 2018

The domination of the news media by the political sphere in Hungary is continuously debated in public and scientific discourses. The issue of migration has resurfaced on the Hungarian political and media agenda following the refugee crisis of 2015. The first part of the paper offers a theoretical overview of frame analysis. Framing refers to making an aspect of an issue salient, thus suggesting a certain interpretation and evaluation of the issue. In the second part, the methodology of frame analysis is used to explore representations of refugees and migrants in two parliamentary speeches of the Hungarian Prime Minister and three online media outlets of different political orientations (Híradó, Index, Origo) in September and November 2015. The results show that the PM framed the issue as a symbolic threat and political conflict, while the media emphasized realistic threats, the politically divided and humanitarian aspect of migration. The article highlights some of the instances where the media does not follow the political discourse.
The power (and problem) of money
Authors: Kövecses Zoltán
Published: October 2018

In the paper, I examine what English idioms related to money reveal about the conceptualization of money. Most money-related idioms in English are based on metaphor. Working with conceptual metaphor theory, I suggest that money idioms in English rely especially on two conceptual metaphors: MONEY IS A MOVING SUBSTANCE / OBJECT / LIQUID and MONEY IS A FORCE. It is well-known that both in everyday talk and expert communication money is conceived of as a MOVING SUBSTANCE / OBJECT / LIQUID. Several studies have dealt with this conceptual metaphor from a cognitive linguistic perspective. However, the FORCE metaphor has received much less attention in the metaphor literature, though it is the latter metaphor that captures the way we view our relationship to money, that is, the way we see the role of money in our life in society. Given this focus, I analyze the FORCE metaphor in some detail, raise the issue of what motivates the emergence of this metaphor, and, finally, address the question of what lends especial cultural significance to it.
What argumentation theory can teach us about commercials: Strategic maneuvering and the ‘tulip test’
Authors: Csordás Hédi Virág , Forrai Gábor
Published: October 2018

The paper seeks to show that the theory of strategic maneuvering, the most recent version of the pragma-dialectical approach to argumentation, can make vital contribution to understanding how commercials are designed and defended against legal challenges. If commercials can be subjected to argumentation-theoretic analysis, that would also show that the idea that commercials never constitute genuine arguments is mistaken. We will begin by sketching the pragma-dialectical approach and the theory of strategic maneuvering, then we apply the latter to two cases: the argument in a commercial aiming to persuade customers that Dove Intensive Cream moisturizes better than Nivea’s similar product, and the argument given by Dove’s manufacturer, Unilever, during the proceedings conducted by the Hungarian Competition Authority, which is intended to convince the Authority that the commercial is not deceptive.
Media messages and eating disorders: Taste and price of a message
Authors: Forgács Attila , Bóna Enikő , Csíkos Tímea , Metercsik Helga
Published: October 2018

Eating habits have become increasingly irrational in the last century; a variety of eating disorders have appeared. Obesity seems to be impossible to cure. Nowadays, the impact of media-marketing is the most powerful social influence on eating habits. Media has five main messages on eating and the body: 1. “Be thin!” 2. “Consume and eat!” 3. “Be afraid of food!” 4. “Food will disappear!” 5. “You are not feminine / masculine enough!” Most of these messages and directions are inconsistent with each other: e.g. “Buy and eat more, but remain thin!” The double-bind communication of media-marketing is pathogenic and schizoid. Food-related media messages are multi-layered and contradictory on many levels, so it would be more appropriate to talk about a multiple bind. The paper offers new communication strategies in order to manage the chaotic information on eating and to decrease the inconsistencies on the topic.
Lower occlusion pressure during resistance exercise with blood-flow restriction promotes lower pain and perception of exercise compared to higher occlusion pressure when the total training volume is equalized
Authors: Soligon SD , Lixandrão ME , Biazon TMPC , Angleri V , Roschel H , Libardi CA
Published: October 2018

Low-intensity resistance exercise with blood-flow restriction (BFR) promotes similar adaptations to high-intensity resistance exercise (HI-RE). Interestingly, BFR has been demonstrated to be effective for a wide range of occlusion pressures. However, the occlusion pressure magnitude may alter the psychophysiological stress related to BFR as measured by rating of perceived exertion scale (RPE) and rating of pain. We aimed to compare the RPE and pain levels across different magnitudes of occlusion pressures, promoting new knowledge regarding occlusion pressure on stress related to BFR. All BFR protocols ranging between 40% and 80% of total arterial occlusion (BFR40, BFR50, BFR60, BFR70, and BFR80) were compared to HI-RE in 12 participants using a randomized and crossover design 72 h apart. BFR protocols and HI-RE were performed with 30% and 80% of one-repetition maximum (1RM) test value, respectively. RPE and pain levels were measured before exercise and immediately after each set. BFR protocols (i.e., BFR40 and BFR50) presented overall lower RPE response compared to higher-pressure BFR (i.e., BFR70 and BFR80) and HI-RE conditions. For pain levels, low-pressure BFRs (i.e., BFR40 and BFR50), and HI-RE showed lower values than high-pressure BFR protocols (i.e., BFR60, BFR70, and BFR80). In conclusion, low-pressure BFR protocols promote lower RPE and pain compared to high-pressure BFR protocols (between 60% and 80% of occlusion pressure), when total training volume (TTV) is equalized. In addition, HI-RE promotes similar levels of pain, but higher RPE than low-pressure BFR, probably due to the higher TTV.
Stigma of substance use in healthcare: A research on contact hypothesis
Authors: Pfitzner K , Kapitány-Fövény M
Published: October 2018

Introduction

Patients suffering from mental disorders and especially substance-use disorders (SUDs) are often stigmatized by both lay individuals and health professionals, which may lead to poorer treatment outcomes. The purpose of this study was to assess the level of stigma against alcohol and drug users among lay respondents and actors of healthcare.

Materials and methods

An online questionnaire was filled out by a total of 148 participants from three subgroups: (a) 25 addictology professionals, (b) 55 emergency care professionals, and (c) 68 lay individuals outside healthcare. The questionnaire contained standardized scales measuring the severity of substance use, authoritarianism, and own items assessing demographics, attitude towards substance users, and substance-related knowledge.

Results

A more accepting attitude towards drug users was explained by the respondents’ own substance use (β = 4.52, p < .01) and knowledge in addictology (β = 2.22, p = .05). Repeated encounters with substance users only showed connection with destigmatization in case of positive experiences. Emergency care professionals were characterized by the most stigmatizing attitude towards substance users.

Discussion

Our results partially support Allport’s contact hypothesis. We emphasize the need of a continuous sensitizing program targeting emergency care professionals in order to change their attitude towards SUD patients.
EKG-gyöngyszem: szerzett hosszú-QT-szindróma
Authors: Tomcsányi János , Tomcsányi Kristóf
Published: October 2018

Abstract:

Authors report the case of a patient with drug-induced long QT syndrome. This case highlights the importance of ECG signs of LQTS that may lead to torsade de pointes tachycardia. The patient received the QT prolonging moxifloxacine and the QT remained long even after the offending drug was discontinued. Orv Hetil. 2018; 159(39): 1607–1610.
Thalassaemiás betegen észlelt anaemia perniciosa – a diagnózis nehézségei
Authors: Kurdi Barnabás , Mezei Zoltán András , Kellner Ádám , Egyed Miklós
Published: October 2018

Abstract:

The bone marrow aspiration, which was done in a leukopenic, hypochromic, microcytic, progressive anemic, thalassemic patient, revealed megaloblastic morphology. The low level of vitamin B12 and the reticulocytosis following the B12 supportation strenghtened the diagnosis of pernicious anemia. The set of the right diagnosis has been delayed by the fact that even in severe anemia one could not obtain the typical signs of B12 deficiency, having a hypochromic, microcytic erythrocyte morphology, due to the thalassemia minor disorder. Orv Hetil. 2018; 159(33): 1368–1371.
Prosztatarákban szenvedő betegek definitív ellátásának tanulságai és modern stratégiái
Authors: Varga Linda , Bajory Zoltán , Pajor László , Révész János , Sükösd Farkas , Maráz Anikó
Published: October 2018

Abstract:

Introduction: Mortality of prostate carcinoma can be significantly decreased by the use of modern diagnostic and therapeutic options. Patients in early stages can be cured by radical surgery or radiotherapy. Aim: Overview and comparison of previous and present diagnostic and therapeutic methods regarding accuracy of diagnosis, improvement of efficiency and decrease of toxicities. We also aimed to explore general correlations in case of serious complications. Method: By the help of two prostate cancer patients we demonstrate the importance of accuracy and change of histological diagnosis, significance of proper imaging techniques, and also show parameters of conventional and modern radiotherapy and their acute and chronic complications. Differences of previous and present methods and their consequences were analyzed. Results: By now, histological findings in the patients’ diagnosis have changed. Both patients received conventional three-dimensional definitive radiotherapy in 2009–2011, and their prostate cancer was cured. In one case, urinary bladder also received radiotherapy because prostate carcinoma had infiltrated it. In the other case, the contemporary radiotherapy involved urinary bladder’s fundus due to safety margins. Although acute grade 2 cystitis developed in both cases and recovered in several weeks, as late complication bladder shrinkage developed, which after the ineffectiveness of conventional therapies had to be cured by radical cystoprostatectomy – in order to cease bleeding and to cure incontinence. Conclusions: In case of prostate carcinomas, serious complications can be avoided by the improvement of diagnostic and therapeutic options. Synthesis of data could be more successful if they were analyzed in the light of previous experiences. Orv Hetil. 2018; 159(32): 1317–1325.
Magyarországi intenzív osztályok szervdonációval kapcsolatos személyi és tárgyi feltételei
Authors: Mihály Sándor , Egyed-Varga Anita , Holtzinger Emese , Kara Kristóf , Ezer Erzsébet , Szedlák Balázs , Smudla Anikó , Nacsa János , Matusovits Andrea
Published: October 2018

Abstract:

Introduction: At the end of 2016, the number of patients on the domestic transplant waiting list was twice as much as the number of the organ transplantations accomplished that year. The institutional prerequisites for functional organ donation programs are the sufficient number of personnel and the adequate material conditions to be provided in relation to the needs. Aim: The goal of the current study was to evaluate the professional environment in Hungary. Method: The Organ Coordination Office at the Hungarian National Blood Transfusion Service compiled a questionnaire survey on the personnel and material conditions of the intensive care units (ICUs) in Hungary in regards to organ donations. The survey applied an online questionnaire including 43 questions. In addition to the number of beds and employees, we investigated the tools needed for the legal and the medical diagnosis of brain death as well as the accessibility of examinations on the donor information form. The data collection spanned from 12 December 2016 to 30 June 2017. Results: 59 intensive care units completed the questionnaire; the investigation involved 640 hospital beds, 816 physicians and 1252 nurses. In the daytime shift, 0.25 doctors and 0.41 nurses work on a patient bed at an average, while in the night shift, the figures are 0.11 and 0.33, respectively. 51.7% of the doctors are registered to access the National Non-Donor Registry, and brain death diagnosis committee is available in 83% of the hospitals. Among the medical imaging methods (cranial, abdominal-thoracic), CT scan in 71–73%, abdominal ultrasound in 75%, transthoracic echocardiograpy (TTE) in 37%, transoesophageal echocardiography (TEE) in 4%, bronchoscopy in 49%, coronarography in 19% are non-stop available, with instant interpretation in 75% of the cases. Transcranial Doppler (TCD) in 30%, four-vessel angiography in 45% and SPECT in 14% of the cases are available. More than 90% of the laboratory examinations on the donor information form are available 24 hours a day. Conclusion: The number of doctors and nurses did not change compared to our 2008 survey (0.18 doctors, 0.37 nurses/ICU beds in 2008), but the care of potential donors needs more resources and time. The standby availability of personnel and material conditions is a prerequisite for organ donation programs in order to save lives. Orv Hetil. 2018; 159(33): 1360–1367.
Az endoszkópos regiszterek szerepe a minőségi betegellátásban. Az új magyar Endoszkópos Retrográd Cholangiopancreatographia (ERCP) Regiszter első eredményei
Authors: Pécsi Dániel , Hegyi Péter , Szentesi Andrea , Gódi Szilárd , Pakodi Ferenc , Vincze Áron
Published: October 2018

Abstract:

Introduction: The continuous monitoring of quality indicators in gastrointestinal endoscopy has become an essential requirement nowadays. Most of these data cannot be extracted from the currently used free text reports, therefore a structured web-based data-collecting system was developed to record the indicators of pancreatobiliary endoscopy. Aim: A structured data-collecting system, the ERCP Registry, was initiated to monitor endoscopic retrograde cholangiopancreatography (ERCP) examinations prospectively, and to verify its usability. Method: From January 2017, all ERCPs performed at the First Department of Medicine, University of Pécs, have been registered in the database. In the first year, the detailed data of 595 examinations were entered into the registry. After processing these data, the testing period of the registry is now finished. Results: On 447 patients, 595 ERCPs were performed. The success rate of cannulation is 93.8% if all cases are considered. Difficult biliary access was noted in 32.1% of patients with native papilla, and successful cannulation was achieved in 81.0% of these cases during the first procedure. Post-ERCP pancreatitis was observed in 13 cases (2.2%), clinically significant post-papillotomy bleeding was registered in 2 cases (0.3%), while 27 patients (4.5%) developed temporary hypoxia during the procedure. 30-day follow-up was successful in 75.5% of the cases to detect late complications. All of the quality indicators determined by the American Society of Gastrointestinal Endoscopy (ASGE) were possible to monitor with the help of the registry. Our center already complies with most of these criteria. Conclusions: Continuous monitoring of the quality indicators of endoscopic interventions are not supported by the current hospital information system but it became possible with our registry. The ERCP Registry is a suitable tool to detect the quality of patient care and also useful for clinical research. Several endoscopy units have joined already this initiative and it is open for further centres through our web page ( https://tm-centre.org/hu/regiszterek/ercp-regiszter/ ). Orv Hetil. 2018; 159(37): 1506–1515.
Nem tapintható tüdőgócok drót- és izotópjelölés segítségével történő minimálinvazív műtéti eltávolítása
Authors: Farkas Attila , Kocsis Ákos , Andi Judit , Sinkovics István , Agócs László , Mészáros László , Török Klára , Bogyó Levente , Radecky Péter , Ghimessy Áron , Gieszer Balázs , Lang György , Rényi-Vámos Ferenc
Published: October 2018

Abstract:

Introduction: Nowadays ever smaller, sub-centimetre lung nodules are screened and diagnosed. For these, minimally invasive resection is strongly recommended both with diagnostic and therapeutic purpose. Aim: Despite many advantages of minimally invasive thoracic surgery, thorough palpation of the lung lobes and thus the localization of lung nodules are still limited. There are several options to solve this problem. From the possibilities we have chosen and tried wire- and isotope-guided lung nodule localization. Materials and methods: In 2017, at the Thoracic Surgery Department of the National Institute of Oncology we performed wire- and isotope-guided minimally invasive pulmonary nodule resection in five patients. The diameter of the lung nodules was between 0.5 and 1.2 cm. The age of the patients was between 44 and 65 years and none of them had severe comorbidities, which meant low risk for complications. Results: We successfully performed the minimally invasive atypical resection in all cases. After the wire and isotope placement we found a 2–3 mm pneumothorax in one patient that did not need urgent drainage. In another patient we found that high amount of intraparenchymal bleeding surrounded the channel of the wire. During the operation, two wires were displaced when the lung collapsed, and in another case the mentioned bleeding got into the thoracic cavity and made it difficult to detect the nodule. In one case we resected the wire-guided lung tissue, but the isotope-guided lung nodule was below the resection line. Conclusion: Both techniques could help to localize the non-palpable lung nodules. Based on our initial experiences, the isotope-guided method provides more details to estimate the exact depth of the nodule from the visceral surface of the pleura and we can avoid the unpleasantness of wire displacement. On the other hand, the production of the isotope requires a more developed infrastructure and the exact timing of the operation after the isotope injection is more strict. Orv Hetil. 2018; 159(34): 1399–1404.
A szegedi Fogászati és Szájsebészeti Klinikán diagnosztizált, az orofacialis régiót érintő jóindulatú daganatok és daganatszerű laesiók klinikopatológiai retrospektív epidemiológiai analízise (1960–2014)
Authors: Sonkodi István , Boda Krisztina , Decsi Gábor , Buzás Kristóf , Nagy Katalin
Published: October 2018

Abstract:

Introduction: In a clinicopathological retrospective epidemiological study we investigated benign tumors and tumor-like lesions located in the orofacial region, diagnosed at the Universiy of Szeged, Department of Oral Medicine. Method: During a 54-year period (1960–2014), 14 661 biopsies were taken. The included subjects were 7491 patients diagnosed with benign tumors and tumor-like lesions. Results: The average age of patients was 55.3 years, 2823 (37.7%) patients were male and 4668 (62.3%) female. The male : female ratio was 1 : 1.65. Most of the patients included in the study were aged 51–60 (1280, 17.1%). The number of children was 1014 (13.6%) and the number of adults was 6477 (86.3%). The number of non-neoplasms was 6420 (85.7%), being significantly higher than the number of neoplasms (1071, 14.3%). Most of the lesions were of mesenchymal origin (5574, 77.4%); the number of lesions of non-mesenchymal origin was 982 (13.1%). The most prevalent type of lesions was traumatic fibroma (fibrosis): 1806 (32.4%). The most common lesion type in the group of lesions of infectious/inflammational origin was pyogenic granuloma, the number of which was 465 (8.3%). The most common cystic lesion was mucocele (805, 10.7%). Hemangioma was the most frequent lesion type among developmental anomalies with the number of 815 (14.6%). The most common location of the lesions was the lip in 2081 cases (27.8%), followed by the gingiva in 2024 cases (27.0%), bucca in 1069 cases (14.3%), tongue in 981 cases (13.1%), and the facial skin in 695 cases (9.3%). After taking biopsy, the majority of benign lesions were treated with cryo-, laser-, or combined (cryo and laser) surgery. Conclusion: The present computer-aided study showed that irritational fibroma was the most common orofacial benign tumor, and the lip was the most frequent location. The diagnostic classification and the methodology are considerably different in the majority of the studies, which may hinder the exact comparison with other surveys from different regions of the world. Orv Hetil. 2018; 159(37): 1516–1524.
Új korszak és új szempontok a transzfúziós kórokozó-átvitel kockázatában, különös tekintettel a rendszeres plazmaeredetű készítményre szoruló haemophiliás betegekre
Authors: Udvardy Miklós
Published: October 2018

Abstract:

Preparative and clinical transfusiology and transfusion, a majestic part of clinical medicine saved the life of hundred millions. However, bloodborne or transmitted infections became a serious issue in France in the 1980s, when many haemophiliacs were infected by HIV or hepatitis C virus by receiving plazma FactorVIII concentrates. This resulted in a quick and powerful development of screening as well as pathogen-inactivating methods, which reduced pathogen contamination and transmission to minimal levels. Times and pathogens are continously and rather quickly changing, so during the last decade many – not only egzotic – new pathogens and diseases were recognised, and some of them (e.g., Zyka virus, Ebola, hepatitis E virus, etc.) can also be transmitted by blood or blood-component transfusions, and in some instances they escape from standard screening and inactivation procedures. Hereby we try to focus and draw attention to some of these potentially pathogenic new bloodborne microbiological agents, and along with this we try to emphasize the significance of application of updated next generation screening and inactivation procedures. Interestingly a recent British trial, based on large population data, showed some evidence of a slight increase of non-Hodgkin lymphoma incidence in patients with multiple previous transfusions. Probably these facts are even more important in haemophiliacs, who receive prophylactic treatment 3 times weekly either by plasma factor concentrates derived from multiple donors or by gene synthetic factor sources. It is important that haemophiliac patient and family should receive the necessary information, and go for a fully informed consent based on the potential advantages and hazards of a particular treatment modality, the same way as in the chronic treatment of other diseases. Orv Hetil. 2018; 159(37): 1495–1500.
Postpartum vérzés ellátása arteria hypogastrica embolisatióval
Authors: Emődi Sándor , Pohánka Róbert , Mosonyi Attila , Dajka Miklós
Published: October 2018

Abstract:

Selective embolization of the hypogastric artery is nowadays commonly used for the haemostasis of gynaecological cancer patients. Also re-embolization is possible in the cases of repeated bleedings. We present this method based on the summary of three obstetrical patients in our hospital. In these patients, primary management failed to control bleeding after parturition caused by anatomic reasons which made it difficult to access the bleeding and to achieve haemostasis. During intervention we catheterized the visceral branch of the internal iliac artery selectively via an access in the common femoral artery. Thereafter we blocked the artery with Spongostan fillings. We had one patient, where we applied embolization in retroperitoneal haemorrhage after Caesarean section and supravaginal amputation of the uterus. In two other cases we successfully managed vaginal haematoma by embolization, whereas multiple surgical treatments were unsuccessful. The advantage of this method is that it does not require laparotomy or vaginal exploration. The disadvantage is that a well-equipped laboratory of angiography and an interventional radiologist are also required. Orv Hetil. 2018; 159(39): 1602–1606.
Újabb lipidológiai evidenciák és ajánlások
Authors: Bajnok László
Published: October 2018

Abstract:

The correlation between cholesterol and risk reduction is unique: no J curve is seen even at extreme low levels. According to PRECISE-IVUS, the effect of intensive cholesterol lowering on plaque regression is more pronounced post-myocardial infarction syndrome than in chronic coronary disease. The importance of LDL-C lowering with ezetimibe in IMPROVE-IT (1.4 mmol/L compared to 1.8 mmol/L in the statin monotherapy arm) is expressed in several international guidelines and the indication spectrum of combination cholesterol lowering has broadened and strengthened. There is a strong evidence that myalgia during statin treatment is generally not caused by statins and it is not related to type or dose of the drug. With patience, the majority of patients can be made to become statin takers even with good quality of life; for those who cannot, ezetimibe monotherapy can be an alternative. Even though intensive cholesterol lowering is safe, avoiding statin myopathy should be emphasized. Despite the outstanding efficacy and safety of cholesterol lowering, Hungarian statin sales have decreased recently, in which driven dilettante public climate around the products may be of utmost importance. Everyone of us should counteract this according to the possibilities. Orv Hetil. 2018; 159(32): 1303–1309.
Az El Camino zarándokút egészségügyi kockázatai. Tanulságok és tanácsok
Authors: Felkai Péter
Published: October 2018

Abstract:

The Way of St. James (El Camino) is getting more and more popular. Analysis of the age groups of the pilgrims shows that the number of young pilgrims (30< years) is decreasing, but the number of middle-aged people (30–60 years) is slightly increasing, while the number of elderly people (>60 years) has considerably increased. The statistical data of the Pilgrims’ office in Santiago de Compostela also display the continuous elevation in the number of the “pilgrims” who had completed the El Camino without any religious or spiritual reason. Therefore this pilgrim route became a long-distance trekking – in the point of view of travel medicine. The old age is a high risk for travellers moreover in this long distance trekking. Therefore pre-travel counselling would be vital for aged pilgrims. Unfortunately, a few articles have been published only on the medical problems of El Camino. Taking into consideration the possible health damages during the 800 km long “Camino”, the author describes its health hazards. This study could be a useful guideline for pre-travel advice for El Camino pilgrims as only limited information can be gained from the Pilgrims’ Reception Office (PRO) in Santiago de Compostela. Some information was collected from the relevant pages of the internet. Therefore the author could draw limited consequences from the statistical data. Yet, the analysis of the medical causes of the deceased pilgrims told more about the hazards of ‘The Way’. Although the number of female and male pilgrims was equal in the statistical data, yet the mortality rate of the male pilgrims is much more higher than that of the female pilgrims (93–7%). The most frequent cause of death was acute coronary syndrome or its suspicion (40–34%). The second most frequent cause of death was road traffic accident (17,5–25%). The most vulnerable pilgrims are the cyclists in this respect. The exacerbation of any chronic disease was also different among the genders (3–25%) but homicide is a more frequent cause of death in the female group (2%–8%). The cause of death was exhaustion, stroke, hypothermia and drowning (because of the ritual bathing in the sea, after the route completed) as well. Orv Hetil. 2018; 159(38): 1535–1542.