bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPLEMENTASI SISTEM PENANGGULANGAN GAWAT DARURAT TERPADU K119 (SPGDT K119) DI KABUPATEN KUDUS
Authors: Mochamad Amad , Arso Septo Pawelas , Setyaningsih Yuliani
Published: January 2022

Sistem Penanggulangan Gawat Darurat Terpadu 119 (SPGDT K119) merupakan salah satu inovasi layanan kesehatan untuk menangani kasus kegawat daruratan di Kabupaten Kudus. Pelaksanaan program SPGDT K119 ini masih dikeluhkan masyarakat, laporan keluhan lambat ditangani, akses call center tidak mudah dihubungi, peran penanganan kasus oleh tim RSUD lebih besar jika dibandingkan dengan tim pelaksana Puskesmas. Tujuan dari penelitian ini untuk menganalisis implementasi sistem penanggulangan gawat darurat terpadu K119 (SPGDT K119) di Kabupaten Kudus. Metode penelitian yang digunakan adalah penelitian kualitatif dengan wawancara mendalam dan observasi. Informan utama dalam penelitian ini terdiri dari 16 orang dan informan triangulasi 4 orang. Hasil penelitian menunjukkan Implementasi SPGDT K119 belum berjalan sesuai yang diharapkan, upaya meningkatkan akses dan mutu pelayanan kegawatdaruratan belum dapat dicapai, koordinasi dan komunikasi antar tim belum efektif, komitmen petugas pelaksana puskesmas belum terbangun, tupoksi serta SOP belum dipahami secara menyeluruh oleh pelaksana. Rekomendasi dari hasil penelitian ini yaitu penggalangan komitmen pemangku kebijakan dan pelaksana, peningkatan koordinasi dan komukasi efektif antar tim, penyediaan sumber daya sesuai kebutuhan program, meningkatkan sosialisasi, dan pelatihan petugas pelaksana. Kata kunci: gawat darurat, penanggulangan dan implementasi
HUBUNGAN ASPEK SOSIAL PEKERJAAN DAN KONDISI KINERJA DENGAN KEPUASAN KERJA PEGAWAI PUSKESMAS DI KABUPATEN KONAWE UTARA
Authors: Rahayu Sri , Saafi La Ode , Munir Sanihu
Published: January 2022

Kepuasan kerja adalah kondisi pada tingkat yang dirasakan seseorang atas peranan atau pekerjaannya dalam sebuah organisasi.  Jadi secara umum  kepuasan kerja menyangkut psikologis individu didalam organisasi, yang diakibatkan oleh keadaan yang ia rasakan dari lingkungannya. PUSKESMAS sebagai pusat kesehatan masyarakat  yang bersentuhan langsung dengan masyarakat merupakan ujung tombak pemerintah dalam bidang kesehatan. Selanjutnya aspek sosial adalah segala hasil aktivitas yang meliputi hubungan manusia dengan alam disekitarnya. Tujuan penelitian in adalah untuk mengetahui faktor-faktor yang berhubungan dengan kepuasan kerja pegawai Puskesmas dan menganalisis hubungan aspek sosial dalam pekerjaan dengan kepuasan kerja. Metode yang digunakan adalah mengginakan literature review yang dipadukan dengan  metode Importance-Performance analysis (analisis tingkat kepentingan dan kinerja/kepuasan) dan kuantitatif. Hasil yang dicaoai adalah dapat mengetahui sejauh mana kepuasan bekerja pada PUSKESMAS berdasarkan pada kebijakan yang ada.  Kesimpulan yang diperoleh bahwa terdapat Hubungan Aspek Sosial Dalam Pekerjaan Dengan Kepuasan Kerja Pegawai Puskesmas Kata Kunci: PUSKESMAS, Kepuasan Kerja,  Importance-Performance analysis
PENGARUH PENDAMPINGAN PETUGAS PENGELOLA OBAT PUSKESMAS TERHADAP PERENCANAAN OBAT DAN KETERSEDIAAN OBAT DI KABUPATEN BUTON UTARA
Authors: Irnawati Irnawati , Sunarsih Sunarsih , Tosepu Ramadhan
Published: January 2022

PUSKESMAS adalah sebuah organiisasi yang memberikan fasilitas pelayanan kesehatan dalam upaya kesehatan masyarakat dan upaya kesehatan perseorangan tingkat pertama, dengan lebih mengutamakan upaya pertolongan pertama, untuk mencapai derajat kesehatan masyarakat yang setinggi-tingginya di wilayah kerjanya. Obat merupakan salah satu komponen utama ynng ada dalam PUSKESMAS dalam rangka pelayanan terhadap masyarakat yang sakit. Tujuan penelitian ini adalah Untuk mengetahui pendampingan pengelola obat Puskesmasdalam meningkatkan perencanaan obat dan ketersediaan obat di Kabupaten Buton Utara. Metode penelitian yang digunakan adalah metode penelitian kuantitatif dengan desain Pre Eksperimen yakni peneliti memberikan perlakuan pada responden penelitian. Hasil penelitian ini dapat menjadi bahan acuan dalam melakukan perencanaan obat sehingga ketersediaan obat di Puskesmas aman dan terjamin serta tepat sasaranserta menjadi acuan untuk pengembangan penelitian selanjutnya. Kesimpulan yang diperoleh bahwa terdapat peningkatan perencanaan obat dan ketersediaan obat terhadap pendampingan petugas pengelola obat puskesmas. Kata Kunci: Puskesmas, Obat,Petugas Pengelola Obat, Pendampingan, Pendampingan
FORMULASI KRIM EKSTRAK DAUN MENGKUDU (Morinda citrifolia L.) SEBAGAI SEDIAAN PELINDUNG SINAR ULTRAVIOLET
Authors: Mugitasari Dessy Erliani , Rahmawati Bela
Published: January 2022

Tabir surya merupakan suatu zat material yang dapat melindungi kulit atau radiasi sinar UV. Senyawa fenolik yang terdapat pada daun mengkudu berfungsi melindungi jaringan tubuh terhadap kerusakan akibat radiasi sinar matahari. Senyawa fenolik khususnya golongan flavonoid mempunyai potensi sebagai tabir surya karena adanya gugus kromofor yang mampu menyerap sinar UV. Pengukuran aktivitas tabir surya dilakukan secara in vitro menggunakan spektrofotometri UV-Vis dengan menentukan nilai SPF dari ektrak daun mengkudu dan krim ekstrak daun mengkudu. Penelitian ini bertujuan untuk memperoleh sedian krim ekstrak daun mengkudu yang baik dengan melakukan uji ekstrak daun mengkudu yang mempunyai aktivitas SPF dan uji parameter sifat fisik yang baik (daya lekat, daya sebar, organoleptis, pH, dan viskositas). Jenis penelitian yang dilakukan  ini adalah penelitian kualitatif yang dilakukan secara eksperimental. Pembuatan krim ekstrak daun mengkudu dilakukan dengan menggunakan menggunakan basis vanishing cream. Krim diformulasikan menjadi tiga variasi konsentrasi yaitu 10%, 15% dan 20%. Uji yang di lakukan meliputi uji organoleptis, uji homogenitas, uji daya lekat, uji daya sebar, dan uji pH. Dari hasil penelitiaan didapatkan hasil pada uji skrinning fitokimia kualitatif ekstrak daun mengkudu adalah positif menggandung flavonoid, saponin, dan tanin. Hasil uji SPF pada variasi konsentrasi ekstrak daun mengkudu 10%, 15%, dan 20% secara berturut-turut sebesar 22.435, 22.397, dan 22.678. Sedangkan nilai SPF pada krim ekstrak daun mengkudu 10%, 15%, dan 20% berturut-turut sebesar 29.902, 29.818, 29.916. Nilai SPF yang paling optimal ditunjukkan pada variasi konsentrasi 20% krim ekstrak daun mengkudu dengan nilai SPF 29,916 yang termasuk dalam kategori proteksi ultra karena range lebih dari 15.
HUBUNGAN PENGGUNAAN GADGET DENGAN INTERAKSI SOSIAL ANAK USIA SEKOLAH DI SDN 02 BANYUURIP KECAMATAN MARGOREJO KABUPATEN PATI
Authors: Rohana Fiidatun , Hartini Sri
Published: January 2022

Perkembangan teknologi dan informasi mengalami kemajuan yang sangat pesat yang di tandai dengan kemajuan pada bidang informasi dan teknologi. Kemajuan teknologi seperti gadget ini tentu memberi dampak positif terutama memudahkan seseorang mencari informasi, mempermudah pekerjaan dan mempersingkat proses informasi baik dalam pekerjaan bidang ekonomi, pendidikan dan lain-lain. Dilain pihak penggunaan yang tidak terkontrolkan memberi dampak negatif bagi penggunanya. Dampak dari permainan gadget itu sendiri adalah mengganggu saraf motorik halus, menghambat perkembangan interaksi sosial, mempengaruhi pola tingkah laku anak, mempengaruhi pola bicara, mudah emosi, terpapar konten kekerasan dan pornografi, bahaya radiasi, pola makan, obesitas, dan susah tidur. Untuk menganalisa hubungan penggunaan gadget dengan interaksi sosial anak usia sekolah di SDN 02 Banyuurip Kecamatan Margorejo Kabupaten Pati. Jenis penelitian ini yang digunakan yaitu kuantitatif dengan menggunakan  metode survey atau penggumpulan data dengan cara pendekatan cross sectional. Populasi sebanyak 39 anak dan sampelnya menggunakan total sampling jadi sampel yang digunakan sebanyak 39 anak. Berdasarkan hasil penelitian menunjukkan paling banyak adalah responden penggunaan gadget tinggi dengan jumlah 23 responden (59,0%), dan paling sedikit adalah penggunaan rendah dengan jumlah 6 responden (15,4%), dan diantarnya adalah penggunaan sedang dengan jumlah 10 responden (25,6%). Penelitian tentang hubungan penggunaan gadget dengan interaksi sosial menghasilkan nilai p value (p 0,000 < ? 0,05) maka terdapat hubungan penggunaan gadget dengan interaksi sosial. Ada hubungan penggunaan gadget dengan interaksi sosial anak usia sekolah di SDN 02 Banyuurip kecamatan margorejo kabupaten pati.
KORELASI LAMA MENDERITA HIPERTENSI DENGAN TINGKAT KECEMASAN PENDERITA HIPERTENSI
Authors: Suciana Fitri , Agustina Nur Wulan , Zakiatul Mifta
Published: January 2022

Hipertensi atau tekanan darah tinggi adalah peningkatan tekanan darah sistolik lebih dari 140 mmHg dan tekanan darah diastolik lebih dari 90 mmHg. Jumlah penyandang hipertensi terus meningkat setiap tahunnya, diperkirakan pada tahun 2025 akan ada 1,5 miliar orang yang terkena hipertensi, dan setiap tahunnya 10,44 juta orang meninggal akibat hipertensi dan komplikasinya. Lama menderita hipertensi akan menyebabkan beberapa komplikasi seperti gagal jantung, gagal ginjal, stroke. Namun selain menimbulkan masalah fisik, hipertensi juga dapat menyebabkan masalah psikologis seperti kecemasan. Tujuan dari penelitian ini adalah mengetahui adakah korelasi antara lama menderita hipertensi dengan tingkat kecemasan penderita hipertensi. Jenis penelitian yang digunakan adalah deskripsi analitik dan menggunakan pendekatan cross sectional dengan jumlah sampel sebanyak 56 responden. Pengambilan data pada penelitian ini menggunakan kuesioner HARS yang dianalisis dengan menggunakan uji kendall tau. Hasilnya adalah sebagian besar dengan hipertensi sedang dengan TD 160-180 mmHg sebanyak 28 responden , lama menderita hipertensi > 11 tahun sebanyak 24 responden, tingkat kecemasan penderita dengan tingkat kecemasan ringan sebanyak 31 responden. Nilai kendall’s tau antara lama menderita hipertensi dan tingkat kecemasan diketahui sebesar 0,417 dengan nilai signifikan 0,000 (< 0,05). Kesimpulan pada penelitian ini adalah adanya hubungan antara lama menderita hipertensi dengan tingkat kecemasan.
PENGARUH TERAPI SPIRITUAL EMOTIONAL FREEDOM TECHNIQUE (SEFT) TERHADAP DEPRESI PADA PASIEN GAGAL GINJAL KRONIS
Authors: Setianingsih Setianingsih , Rahayuningsih Tri , Agustina Nur Wulan
Published: January 2022

ABSTRAK Pasien gagal ginjal yang menjalani hemodialisis seringkali mengalami depresi, akibat perasaan sedih memikirkan penyakit yang diderita yang tidak kunjung sembuh, adanya efek samping dari terapi hemodialisis, dan memikirkan banyaknya biaya pengobatan yang harus dikeluarkan. Salah satu terapi untuk mengatsi perasaan depresi pada pasien gagal ginjal dengan terapi hemodialisa dapat diberikan   Spiritual Emotional Freedom Technique (SEFT). Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian Spiritual Emotional Freedom Technique (SEFT) dalam menurunkan tingkat depresi pada pasien gagal ginjal dengan terapi hemodialisa. Penelitian ini menggunakan desain pre experiment. Jumlah sampel penelitian sebanyak 10 pasien gagal ginjal yang menjalani hemodialisis di RSU PKU Muhammadiyah Delanggu Klaten. Alat pengumpulan data menggunakan Beck Depression Inventory (BDI).  Intervensi berupa Spiritual Emotional Freedom Technique (SEFT) diberikan kepada semua responden. Yang kemudian dibandingkan tingkat depresi pre dan post terapi SEFT. Teknik analisis data menggunakan analisis univariat dan bivariat dengan uji statistik Paired t-test. Hasil penelitian diperoleh: (1) Usia pasien sebagian besar berusia antara 45-58 tahun (70%), dan termasuk usia pertengahan memasuki periode lanjut usia; (2) Berdasarkan jenis kelamin, hampir seluruhnya adalah laki-laki (90%); (3) Tingkat pendidikan pasien sebagian besar lulus SLTA sederajat (30%) dan lulus perguruan tinggi (30%); 94) Jenis pekerjaan pasien sebagian besar adalah buruh (40%), PNS/pensiunan (20%), dan tidak bekerja (20%); 95) Seluruh pasien menjalani hemodialisis dalam kurun waktu kurang dari 2 tahun (100%). Hasil uji Paired T-test antara skor pre test dan post test diperoleh angka p value = 0,001 < 0,05 yang  menunjukan ada pengaruh signifikan. Kesimpulan penelitian ini adalah terapi SEFT dapat menurunkan tingkat tingkat deperesi pasien gagal ginjal yang menjalani hemodialisis. Kata kunci : Gagal ginjal, Hemodialisis, Depresi, terapi SEFT
PENGETAHUAN STANDART LABELING TRIAGE DENGAN TINDAKAN KEGAWATAN BERDASARKAN STANDART LABELING TRIAGE
Authors: Zahroh Roihatul , Basri Ahmad Hasan , Kurniawati Elok
Published: January 2022

ABSTRAK Pengetahuan tentang standart labeling triase erat kaitannya dengan tindakan kegawatan berdasarkan standart labeling triase. Tujuan penelitian ini adalah untuk menganalisis hubungan pengetahuan tentang standart labeling triase dengan tindakan kegawatan berdasarkan standart labeling triase di  Instalasi Gawat Darurat. Metode yang digunakan adalah desain penelitian cross sectional dengan subyek penelitian sebanyak 24 orang dengan metode total sampling di Instalasi Gawat Darurat RSUD Bhakti Dharma Husada. Dengan variabel independen adalah pengetahuan tentang standart labeling triase dilihat dengan kuesioner dan variabel dependen tentang tindakan perawat berdasarkan standart labeling triase dilakukan dengan observasi. Selanjutnya data diolah menggunakan analisis spearman rank corelation dengan signifikasi < 0,05. Hasil penelitian dengan uji statistik spearman’s rho didapatkan nilai signifikan (2-tailed)= 0,002 yang berarti ada hubungan pengetahuan tentang triase. Sedangkan nilai kolerasi = 0,590 artinya ada derajat hubungan kuat antara pengetahuan tentang standart labeling triase dengan tindakan kegawatan berdasarkan standart labeling triase. Dari hasil penelitian ini diharapkan adanya gambaran bagi perawat bahwa begitu besarnya pengaruh pengetahuan dalam penangan penderita gawat darurat. Sehingga termotivasi untuk melakukan tindakan yang lebih baik dengan cara peningkatan pengetahuan dengan diskusi/seminar, pelatihan atau melanjutkan pendidikan formal. Kata Kunci: Pengetahuan, Tindakan Kegawatan, Standart Labeling Triase
PENGARUH KONSUMSI TEH DAUN KELOR TERHADAP PENINGKATAN PRODUKSI ASI DI GROBOGAN
Authors: Purnanto Nurulistyawan Tri , Himawati Laily , Ajizah Nur
Published: January 2022

ABSTRAK Rendahnya cakupan ASI eksklusif di Indonesia menjadikan anak terkurangi haknya untuk mendapatkan makanan bernutrisi tinggi bagi pertumbuhan. Hal ini dikarenakan kurangnya produksi ASI pada ibu menyusui. Pemberian tindakan non farmakologi seperti teh daun kelor diharapkan mampu meningkatkan produksi ASI sehingga anak tetap mendapatkan ASI. Penelitian ini bertujuan untuk untuk mengetahui pengaruh konsumsi teh daun kelor terhadap peningkatan produksi ASI di Kabupaten Grobogan. Metode penelitian ini berjenis quasi experimental study dengan menggunakan one group prepost test design pada 60 responden. Intervensi dilakukan selama 3 minggu untuk menilai produksi ASI antara Pre dan Post intervensi. Data dianalisa dengan menggunakan Uji Paired t-Test. Hasil penelitian menunjukkan rata-rata ASI pada tahap pre-test sebanyak 152,00 meningkat menjadi 158,50 pada tahap post-test. Terdapat perbedaan jumlah ASI dengan p-value sebesar 0,002 dengan nilai korelasi sebesar 0,934. Kesimpulan penelitian ini adalah terdapat pengaruh yang signifikan pada konsumsi teh daun kelor untuk produksi ASI.  Kata Kunci : Teh Daun Kelor, Produksi ASI
Neurosurgical versus endovascular treatment of craniocervical junction arteriovenous fistulas: a multicenter cohort study of 97 patients
Authors: Takai Keisuke , Endo Toshiki , Seki Toshitaka , Inoue Tomoo , Koyanagi Izumi , Mitsuhara Takafumi , _ _ , _ _ , Ito Keisuke , Iwasaki Motoyuki , Uchikado Hisaaki , Umebayashi Daisuke , Otsuka Munehiro , Ohtonari Tatsuya , Oda Junpei , Kageyama Hiroto , Kurokawa Ryu , Koizumi Satoshi , Sugawara Taku , Takeshima Yasuhiro , Nagashima Yoshitaka , Nishikawa Misao , Fujimoto Masashi , Honda Fumiaki , Matsui Seishi , Matsumoto Yoshihisa , Miyoshi Yasuyuki , Murata Hidetoshi , Yasuhara Takao , Yamahata Hitoshi , Yamamoto Shinji , Yamamoto Yu
Published: January 2022

OBJECTIVE

Craniocervical junction (CCJ) arteriovenous fistulas (AVFs) are treated using neurosurgical or endovascular options; however, there is still no consensus on the safest and most effective treatment. The present study compared the treatment results of neurosurgical and endovascular procedures for CCJ AVFs, specifically regarding retreatment, complications, and outcomes.

METHODS

This was a multicenter cohort study authorized by the Neurospinal Society of Japan. Data on consecutive patients with CCJ AVFs who underwent neurosurgical or endovascular treatment between 2009 and 2019 at 29 centers were analyzed. The primary endpoint was the retreatment rate by procedure. Secondary endpoints were the overall complication rate, the ischemic complication rate, the mortality rate, posttreatment changes in the neurological status, independent risk factors for retreatment, and poor outcomes.

RESULTS

Ninety-seven patients underwent neurosurgical (78 patients) or endovascular (19 patients) treatment. Retreatment rates were 2.6% (2/78 patients) in the neurosurgery group and 63% (12/19 patients) in the endovascular group (p < 0.001). Overall complication rates were 22% and 42% in the neurosurgery and endovascular groups, respectively (p = 0.084). Ischemic complication rates were 7.7% and 26% in the neurosurgery and endovascular groups, respectively (p = 0.037). Ischemic complications included 8 spinal infarctions, 2 brainstem infarctions, and 1 cerebellar infarction, which resulted in permanent neurological deficits. Mortality rates were 2.6% and 0% in the neurosurgery and endovascular groups, respectively (p > 0.99). Two patients died of systemic complications. The percentages of patients with improved modified Rankin Scale (mRS) scores were 60% and 37% in the neurosurgery and endovascular groups, respectively, with a median follow-up of 23 months (p = 0.043). Multivariate analysis identified endovascular treatment as an independent risk factor associated with retreatment (OR 54, 95% CI 9.9–300; p < 0.001). Independent risk factors associated with poor outcomes (a postoperative mRS score of 3 or greater) were a pretreatment mRS score of 3 or greater (OR 13, 95% CI 2.7–62; p = 0.001) and complications (OR 5.8; 95% CI 1.3–26; p = 0.020).

CONCLUSIONS

Neurosurgical treatment was more effective and safer than endovascular treatment for patients with CCJ AVFs because of lower retreatment and ischemic complication rates and better outcomes.
Flow augmentation STA-MCA bypass evaluation for patients with acute stroke and unilateral large vessel occlusion: a proposal for an urgent bypass flowchart
Authors: Sebök Martina , Esposito Giuseppe , Niftrik Christiaan Hendrik Bas van , Fierstra Jorn , Schubert Tilman , Wegener Susanne , Held Jeremia , Kulcsár Zsolt , Luft Andreas R. , Regli Luca
Published: January 2022

OBJECTIVE

Endovascular recanalization trials have shown a positive impact on the preservation of ischemic penumbra in patients with acute large vessel occlusion (LVO). The concept of penumbra salvation can be extended to surgical revascularization with bypass in highly selected patients. For selecting these patients, the authors propose a flowchart based on multimodal MRI.

METHODS

All patients with acute stroke and persisting internal carotid artery (ICA) or M1 occlusion after intravenous lysis or mechanical thrombectomy undergo advanced neuroimaging in a time window of 72 hours after stroke onset including perfusion MRI, blood oxygenation level–dependent functional MRI to evaluate cerebrovascular reactivity (BOLD-CVR), and noninvasive optimal vessel analysis (NOVA) quantitative MRA to assess collateral circulation.

RESULTS

Symptomatic patients exhibiting persistent hemodynamic impairment and insufficient collateral circulation could benefit from bypass surgery. According to the flowchart, a bypass is considered for patients 1) with low or moderate neurological impairment (National Institutes of Health Stroke Scale score 1–15, modified Rankin Scale score ≤ 3), 2) without large or malignant stroke, 3) without intracranial hemorrhage, 4) with MR perfusion/diffusion mismatch > 120%, 5) with paradoxical BOLD-CVR in the occluded vascular territory, and 6) with insufficient collateral circulation.

CONCLUSIONS

The proposed flowchart is based on the patient’s clinical condition and multimodal MR neuroimaging and aims to select patients with acute stroke due to LVO and persistent inadequate collateral flow, who could benefit from urgent bypass.
Electrical stimulation–induced speech-related negative motor responses in the lateral frontal cortex
Authors: Zhou Yuyao , Zhao Zehao , Zhang Jie , Hameed N. U. Farrukh , Zhu Fengping , Feng Rui , Zhang Xiaoluo , Lu Junfeng , Wu Jinsong
Published: January 2022

OBJECTIVE

Speech arrest is a common but crucial negative motor response (NMR) recorded during intraoperative brain mapping. However, recent studies have reported nonspeech-specific NMR sites in the ventral precentral gyrus (vPrCG), where stimulation halts both speech and ongoing hand movement. The aim of this study was to investigate the spatial relationship between speech-specific NMR sites and nonspeech-specific NMR sites in the lateral frontal cortex.

METHODS

In this prospective cohort study, an intraoperative mapping strategy was designed to identify positive motor response (PMR) sites and NMR sites in 33 consecutive patients undergoing awake craniotomy for the treatment of left-sided gliomas. Patients were asked to count, flex their hands, and simultaneously perform these two tasks to map NMRs. Each site was plotted onto a standard atlas and further analyzed. The speech and hand motor arrest sites in the supplementary motor area of 2 patients were resected. The 1- and 3-month postoperative language and motor functions of all patients were assessed.

RESULTS

A total of 91 PMR sites and 72 NMR sites were identified. NMR and PMR sites were anteroinferiorly and posterosuperiorly distributed in the precentral gyrus, respectively. Three distinct NMR sites were identified: 24 pure speech arrest (speech-specific NMR) sites (33.33%), 7 pure hand motor arrest sites (9.72%), and 41 speech and hand motor arrest (nonspeech-specific NMR) sites (56.94%). Nonspeech-specific NMR sites and speech-specific NMR sites were dorsoventrally distributed in the vPrCG. For language function, 1 of 2 patients in the NMA resection group had language dysfunction at the 1-month follow-up but had recovered by the 3-month follow-up. All patients in the NMA resection group had fine motor dysfunction at the 1- and 3-month follow-ups.

CONCLUSIONS

The study results demonstrated a functional segmentation of speech-related NMRs in the lateral frontal cortex and that most of the stimulation-induced speech arrest sites are not specific to speech. A better understanding of the spatial distribution of speech-related NMR sites will be helpful in surgical planning and intraoperative mapping and provide in-depth insight into the motor control of speech production.
NILAI USAHA INDUSTRI PRIMER HASIL HUTAN KAYU PADA CV SINAR JAYA DI KECAMATAN CIGUDEG KABUPATEN BOGOR
Authors: Pradipta Gayuh Angga , Susdiyanti Tun , Supriono Bambang
Published: January 2022

Community forests are the source of raw materials for the Primary Wood Forest Products Industry at CV Sinar Jaya in Cigudeg District, Bogor Regency. Optimizing the use of these raw materials can affect the business value of the wood processing industry. The purpose of this study was to determine the yield value and to analyze the business value of sawmill activities at CV. Sinar Jaya. The research method was carried out by means of quantitative analysis methods of collecting production data by direct measurement and interviews as well as calculating the value of economic income obtained from sawmill activities and overall waste utilization, the size of wood raw materials includes 10 centimeters to 30 centimeters with a length of 2 ,8 meters to 3 meters. The results showed that the average yield value is 55%, productivity is 1.51 m3/hour round wood, sawn wood is 0.83 m3/hour production cost is Rp 1,181,600,000.0/year, Income value is Rp. 1,509,600,0000.00/year, net profit value is Rp. 328,000.00/year, the value of marketing costs is Rp. 0 the value of the benefit cost ratio is 1.28/year and the work performance value of logs is Rp. 12,712.89 sawn wood Rp. 22,867.14. To increase the yield, the skills of the sawing workforce must be improved to minimize damage toeach sortimen. In order for business value to increase, productivity must be intensified and the availability of raw materials must be sustainable.
KARAKTERISTIK SPASIAL DAN POTENSI CADANGAN KARBON DI BENTANG ALAM MBELILING NUSA TENGGARA TIMUR
Authors: Oktian Serlina H. , Setyaningsih Luluk , Anen Nengsih , Adinugroho Wahyu C.
Published: January 2022

Providing comprehensive information on carbon stock data on all carbon pools needs to be done to plan and measure climate change mitigation efforts that are carried out. This research was conducted by analyzing spatial characteristics and estimating carbon stocks with model development. Spatial analysis is carried out to provide an overview of the distribution of spatial values that can use the built model. Estimation of carbon stock is carried out by building a carbon stock estimator model that correlates the value of remote sensing parameters with the value of carbon stocks in all carbon storage sources. The characteristics of the vegetation index value in the forest category are greater than in the non-forest category and vice versa for the distribution of the digital number average value. The model development is only carried out on aboveground biomass and belowground biomass carbon pools. The results of the analysis of the estimation of carbon stocks based on the selected model showed the potential for aboveground biomass was 5,200,841.45 tC and the potential for belowground biomass was 1,317,948.10 tC.
NILAI EKONOMI KEGUNAAN WISATA ALAM SITUGUNUNG TAMAN NASIONAL GUNUNG GEDE PANGRANGO
Authors: Rezki Amala , Lidiawati Ina , Supriono Bambang
Published: January 2022

The Situgunung area has direct usability value as recreation place and natural tourism. This study aims to determine the perception of visitors and the economic value usability on the natural tourism of Situgunung. This research method uses descriptive methods as well as traveling expenses or the Travel Cost Method (TCM). Testing the perception of visitors using validity and reliability tests were analyzed descriptively using a Likert scale and the economic value use was analyzed using the concept of travel cost (TCM). This result of the study indicates the index of visitors’ perceptions of Situgunung Nature Tourism from the beauty is 89,25% very beautiful, the security aspect is 83,5 % very safe, the hygiene aspect is 77,5% very clean, the accessibility aspect is 77,75% very easy, the facility aspect is 74,25% complete. And the economic value of the use of Situgunung Nature Tourism is Rp.49.197.122.816/year, with the average traveling expenses calculated based on the zone or distance from the area from which the visitor came to the tourist location. With the high perception of visitors and the value of economic use of Situgunung Nature Tourism objects, a more professional management is needed without reducing the concept of natural sustainability.
PENGARUH RESIN TERHADAP PERUBAHAN WARNA PADA CAT TEMBOK
Authors: Nurlela Nurlela , Risnawati Risnawati
Published: January 2022

The Influence of Resin against the Change of Color on the Wall PaintThe quality of the paint is determined by the resin used. Synthetic resins for polymer paints are made by combining several monomers to achieve various characteristics. The incorporation of some monomers such as polyvinyl acetate resin, acrylic vinyl resin and acrylic styrene resin which act as a binder can affect the quality of the paint especially the color change. The purpose of this study is to find the color changes that occur on the wall paint by using Poly Styrene Acrylic , Poly Vinyl Acetate and Poly Vinyl Acrylic. From the results of the measurement of color difference, significant color change occurs in the Poly Vinyl Acetate (PVAc) + Poly Vinyl Acrylic (PVA) and Poly Styrene Acrylic (PSA). The results of the quality test of the three resins based on pH test, scrub test and viscosity test, PSA has better quality compared to PVA + PVAc and PVA resin. From the color difference measurement test, some things need to be considered, are temperature, film thickness, substrate color/background color and measurement conditions (measured in wet sample/in plate/dry surface) and test on resin added additive according to the type of each resin.Keywords: Paint, Resin, Color Changes, Poly Vinyl Acetate, Poly Styrene.ABSTRAK Kualitas dari cat sangat ditentukan oleh resin yang digunakan. Resin sintetis untuk cat berupa polimer yang dibuat dengan menggabung beberapa monomer untuk mencapai berbagai karakteristik. Penggabungan dari beberapa monomer seperti resin poli vinil asetat, resin vinil akrilik dan resin stirena akrilik yang berfungsi sebagai pengikat mampu mempengaruhi kualitas cat terutama dari perubahan warna. Tujuan dari penelitian ini adalah untuk mengetahui perubahan warna yang terjadi pada cat tembok dengan menggunakan Poli Stirena Akrilik, Poli Vinil asetat dan Poli Vinil Akrilik. Dari hasil pengukuran perbedaan warna, perubahan warna cukup signifikan terjadi pada resin Poli vinil Asetat (PVAc) + Poli Vinil Akrilik (PVA) dan resin  Poli Stirena Akrilik (PSA). Hasil uji Kualitas cat dari ketiga resin berdasarkan uji pH, uji scrub dan uji viscositas, PSA memiliki kualitas yang lebih baik dibandingkan dengan resin PVA+PVAc dan PVA. Dari pengujian pengukuran perbedaan warna, beberapa hal yang perlu di perhatikan, yaitu suhu, film thickness, warna substrat/background color dan kondisi pengukuran (diukur dalam keadaan wet sample/dalam bentuk plate/dry surface) dan pengujian terhadap resin yang ditambahkan zat aditif yang sesuai dengan tipe masing-masing resin tersebut.Kata Kunci: Cat, Resin, Perubahan Warna, Poli Vinil, Poli Stirena.
KANDUNGAN KIMIA DARI LIMBAH LUMPUR INSTALASI PENGOLAHAN AIR MINUM UNTUK BETON GEOPOLIMER DENGAN XRF
Authors: Nuryanti Nuryanti , Arizal Ridha , Arrisujaya Dian
Published: January 2022

Chemical Containt of Waste Water Installation of Drinking Water Treatment for Geopolymer Concrete by XRF Preparation of geopolymer concrete from waste water installation of drinking water treatment (WIDWT) was manufactured in accordance with SNI. Specimen of size 5 x 5 x 5 cm cubes was used for the concretes. The mortar material consisted of binders, activator, aggregate (fine sand) and water (60% of aggregate and 40% of activators and binders). The composition of the activator and binder mixture were 1: 2; 1: 1,5; 1: 1; 1.5: 1; and 2: 1. The results of the comparison of binders A and B were 4.2: 1 and 6.5: 1. The binders were divided into 2 types: A binder (sludge of WIDWT was dried with oven at 105oC for 24 hours) and B Binder (sludge of WIDWT was dried by kiln at 650oC for 6 hours). The highest compressive strength test was 10.00 MPa on binder A with the ratio of activator and binder 1: 1 and Si: Al ratio (4.2: 1). Binder B with a compressive strength of 9.87 MPa with the ratio of activator and binder 1.5: 1 and Si: Al ratio (6.5: 1). Samples of IPAM sludge waste were tested by X-Ray Fluorescence (XRF), compressive strength testing of mortar geopolymer with Toni-Technik compressive strength test. The highest value of compressive strength appropriated to SNI 03-0691-1996 in class D which can be applied for City Park.Keywords: geopolymer, WIDWT, XRF, activator, binder ABSTRAK Pembuatan beton geopolimer dari limbah instalasi pengolahan air minum (IPAM) telah dilakukan. Beton geopolimer dibuat sesuai dengan SNI pembuatan mortar geopolimer dengan ukuran 5 x 5 x 5 cm. Bahan mortar terdiri dari binder, larutan aktivator dan agregat (pasir halus) serta air dengan perbandingan 60% (agregat) dan 40%(aktivator dan binder). Parameter variasi campuran aktivator dan binder yaitu 1:2; 1:1,5; 1:1; 1,5:1; dan 2:1. Binder dibagi menjadi 2 jenis yaitu Binder A (lumpur IPAM yang dikeringkan dengan oven pada suhu 105oC selama 24 jam) dan Binder B (lumpur IPAM yang dikeringkan dengan tanur pada suhu 650oC selama 6 jam). Hasil perbandingan binder A dan B adalah 4,2:1 dan 6,5:1. Hasil uji kuat tekan tertinggi sebesar 10,00 Mpa pada binder A dengan perbandingan aktivator dan binder 1:1 dengan perbandingan Si:Al (4,2:1). Binder B dengan kuat tekan 9,87 Mpa dengan perbandingan aktivator dan binder 1,5:1 dengan perbandingan Si:Al (6,5:1). Sampel limbah lumpur IPAM diuji dengan X-Ray Flourescene (XRF), pengujian kuat tekan mortar geopolimer dengan alat uji kuat tekan merk Toni-Technik. Nilai kuat tekan tertinggi memasuki persyaratan mutu SNI 03-0691-1996 pada kelas D yang bisa diaplikasikan untuk taman kota.Kata Kunci: geopolimer, IPAM, XRF, aktivator, binder
Evaluating and extending the Informed Consent Ontology for representing permissions from the clinical domain
Authors: Umberfield Elizabeth E. , Stansbury Cooper , Ford Kathleen , Jiang Yun , Kardia Sharon L.R. , Thomer Andrea K. , Harris Marcelline R.
Published: January 2022

The purpose of this study was to evaluate, revise, and extend the Informed Consent Ontology (ICO) for expressing clinical permissions, including reuse of residual clinical biospecimens and health data. This study followed a formative evaluation design and used a bottom-up modeling approach. Data were collected from the literature on US federal regulations and a study of clinical consent forms. Eleven federal regulations and fifteen permission-sentences from clinical consent forms were iteratively modeled to identify entities and their relationships, followed by community reflection and negotiation based on a series of predetermined evaluation questions. ICO included fifty-two classes and twelve object properties necessary when modeling, demonstrating appropriateness of extending ICO for the clinical domain. Twenty-six additional classes were imported into ICO from other ontologies, and twelve new classes were recommended for development. This work addresses a critical gap in formally representing permissions clinical permissions, including reuse of residual clinical biospecimens and health data. It makes missing content available to the OBO Foundry, enabling use alongside other widely-adopted biomedical ontologies. ICO serves as a machine-interpretable and interoperable tool for responsible reuse of residual clinical biospecimens and health data at scale.
Spectral asymptotics for the Schrödinger operator with a non-decaying potential
Authors: Dimassi Mouez , Fujiié Setsuro
Published: January 2022

We study Schrödinger operators [Formula: see text] acting in [Formula: see text] for non-decaying potentials V. We give a full asymptotic expansion of the spectral shift function for a pair of such operators in the high energy limit. In particular for asymptotically homogeneous potentials W at infinity of degree zero, we also study the semiclassical asymptotics to give a Weyl formula of the spectral shift function above the threshold [Formula: see text] and Mourre estimates in the range of W except at its critical values.
Contrast-enhanced ultrasound for evaluating response to pulsed-wave high-intensity focused ultrasound therapy in advanced pancreatic cancer
Authors: Yang Yu , Shi Xian-quan , Chen Guang , Zhou Xiao-na , Qian Lin-xue
Published: January 2022

OBJECTIVE: To examine whether contrast-enhanced ultrasound (CEUS) parameters in patients with advanced pancreatic cancer could be used to assess response to treatment with pulsed-wave high intensity focused ultrasound (PW-HIFU). METHODS: We prospectively recorded the pretreatment and posttreatment CEUS related parameters, CA19-9, pain scores of 30 patients with advanced pancreatic cancer treated with PW-HIFU treatment. Correlation of clinical parameters, tumor characteristics, and PW-HIFU treatment energy with CEUS parameters were analyzed. RESULTS: Pain score decreased after treatment (from 4.80±2.14 to 3.28±1.93, p = 0.001). CA19-9 dropped in RT decreased group, 4 weeks after one session PW-HIFU, compared with prolonged group (p = 0.013). According to the display of blood vessels in the mass by CEUS, tumors were classified by vessel grade (VG), VG1: no vessel can be seen; VG 2: vessels diameter < 5 mm; VG 3: vessels diameter > 5 mm. VGs were different between increased and decreased relative rise intensity (rRI) groups (p = 0.008). VG1 group shown a decreased rRI after treatment, while VG3 group showed the opposite trend (p = 0.006). CONCLUSIONS: CEUS can evaluating response to PW-HIFU in advanced pancreatic cancer. Quantitative analysis may help to assess the short-term efficacy of patients and help for individualized treatment.
Singleton pregnancy losses before gestational week 22 among patients with autoimmune disorders and methylenetetrahydrofolate reductase polymorphisms
Authors: Cagan Murat , Okuducu Ummuhan , Donmez Hanife Guler , Beksac Mehmet Sinan
Published: January 2022

BACKGROUND: The rates of pregnancy losses (PLs) are increased by maternal risk factors such as autoimmune disorders (AD) and methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms. OBJECTIVE: To evaluate singleton PLs before gestational week (gw) 22 among patients with AD and MTHFR polymorphisms. METHODS: Totally, 1108 singleton pregnancies in 243 women were categorized as: 1) 148 pregnancies in 33 patients with AD, 2) 316 pregnancies in 66 patients with MTHFR polymorphisms, 3) 644 pregnancies in 144 patients with AD +MTHFR polymorphisms. PLs were classified into subgroups: a) Chemical Pregnancy(CP), b) Blighted Ovum(BO), c) gw ⩽ 10, d) gw11–14 e) gw15–22, f) Ectopic Pregnancy(EP), g) Trophoblastic Disease(TD). Obstetric histories were compared using Beksac Obstetrics Index (BOI): [number of living child + (π/10)]/gravida. RESULTS: PL rates before gw22 were 39.2% (58/148), 33.2% (105/316), and 36.3% (234/644) in AD, MTHFR, and AD +MTHFR groups, respectively (p= 0.421). The rate of Pre-Prenatal Screening Period fetal losses (CP + BO + gw ⩽ 10 fetal losses + EP + TD) were 84.8%, 75.9%, and 77.8% in AD, MTHFR, and AD +MTHFR, respectively (p= 0.264). Gravidity ⩽ 4 versus those with gravidity ⩾ 5 had statistically significant differences in BOI (p< 0.001). CONCLUSIONS: PL rate before gw22 among singleton pregnancies with AD and/or MTHFR polymorphisms was 35.8%. The clinical findings seem to be more complicated in patients with gravidity ⩾ 5.
Performance and planning model for HEIs: A developmental engine for intellectual capital
Authors: Al-Hemyari Zuhair A. , AlSarmi Abdullah M.
Published: January 2022

BACKGROUND:

HEIs implement different techniques for the problem of assessing the progress towards the notified goals or the achievements, which is the only way to ensure that the HEIs are functioning properly along the right way or not.

OBJECTIVE:

The aim of this paper is to propose a model for assessing the performance, which may be of interest to institutions, partners, society and students.

METHODS:

In this paper, the technique of performance-related goals of HEIs, and a statistical approach are proposed. The methodology of this paper will manage briefly the issues of the applicability of the technique, how to derive the “goals” for HEI’s, taking into consideration the indicators of the Intellectual Capital (Human, Organizational, and Relational), and how to collect the data from HEIs successfully. The processes of assuring the technique of performance-related goals, deriving and implementing the goals, and the acquisition and testing of data are developed.

RESULTS:

The findings of this paper are in two directions, i.e. in the proposing of a performance model for HEIs which is based on the goals of HEIs; and in the application side, i.e. in the practical results of the evaluation of HEIs and how to clarify the performance of institutions and how to compare between them. The findings show that the practical results are significant, and reliable.

CONCLUSIONS:

This paper develops a significance model for performance appraisal of HEIs, how we can compare between the performance of HEIs, and to rank their performance. The practical results of the model are both accurate and significant.
Nonlinear Relationship of Non-High-Density Lipoprotein Cholesterol and Cognitive Function in American Elders: A Cross-Sectional NHANES Study (2011–2014)
Authors: Zhang Qiaoyang , Zhang Min , Chen Yun , Cao Yin , Dong Guanzhong
Published: January 2022

Background: Serum non-high-density lipoprotein-cholesterol (non-HDL-C) levels may be associated with cognitive function. Objective: The objective of this study was to evaluate the association between non-HDL-C and cognitive function among American elders. Methods: We used data from the 2011 to 2014 U.S. National Health and Nutrition Examination Survey (NHANES). A total of 3,001 participants aged over 60 years were enrolled in our analysis. The cognitive function was evaluated with the word learning subtest from the Consortium to Establish a Registry for Alzheimer’s disease (CERAD W-L), the Animal Fluency Test (AFT), and the digit symbol substitution test (DSST). We also created a composite cognitive z-score to represent a global cognition. We applied multivariate linear regression analyses to estimate the associations between non-HDL-C levels and all domains of cognitive function. Further, the generalized additive model and the smooth curve were conducted to investigate the dose-response relationship between non-HDL-C and global cognition. Results: Serum non-HDL-C was positively associated with global cognition (β= 0.20, 95% CI: 0.11, 0.28), AFT score (β= 0.54, 95% CI: 0.33, 0.76), and DSST score (β= 1.13, 95% CI: 0.56, 1.69) after fully adjusted. While non-HDL-C was not related to CERAD W-L score. In addition, an inverted U-shape curve was observed in the dose-response relationship between non-HDL-C and global cognition (p for non-linearity < 0.001). Conclusion: Serum non-HDL-C is positively and nonlinearly associated with cognitive function among American older adults. Maintaining serum cholesterol levels at an appropriate range may be helpful to the cognitive health of the elderly.
Protective Effect of Rivaroxaban Against Amyloid Pathology and Neuroinflammation Through Inhibiting PAR-1 and PAR-2 in Alzheimer’s Disease Mice
Authors: Bian Zhihong , Liu Xia , Feng Tian , Yu Haibo , Hu Xiao , Hu Xinran , Bian Yuting , Sun Hongming , Tadokoro Koh , Takemoto Mami , Yunoki Taijun , Nakano Yumiko , Fukui Yusuke , Morihara Ryuta , Abe Koji , Yamashita Toru
Published: January 2022

Background: Recent studies have revealed that atrial fibrillation (AF) patients have a high risk of developing cognitive impairment, vascular dementia, and Alzheimer’s disease (AD). Some reports suggest that the application of oral anticoagulant with an appropriate dose may have a preventive effect on AD. However, which oral anticoagulant drug is more appropriate for preventing AD and the underlying mechanism(s) is still unknown. Objective: The aim of the present study was to assess the treatment effect of rivaroxaban administration as well as investigate the roles of PAR-1 and PAR-2 in the AD + CAA mice model. Methods: In the present study, we compared a traditional oral anticoagulant, warfarin, and a direct oral anticoagulant (DOAC), rivaroxaban, via long-term administration to an AD with cerebral amyloid angiopathy (CAA) mice model. Results: Rivaroxaban treatment attenuated neuroinflammation, blood-brain barrier dysfunction, memory deficits, and amyloid-β deposition through PAR-1/PAR-2 inhibition in the AD + CAA mice model compared with warfarin and no-treatment groups. Conclusion: The present study demonstrates that rivaroxaban can attenuate AD progress and can be a potential choice to prevent AD.
Picture fuzzy MABAC method based on prospect theory for multiple attribute group decision making and its application to suppliers selection
Authors: Jiang Zhiwei , Wei Guiwu , Guo Yanfeng
Published: January 2022

In the garment manufacturing industry, purchasing management is an important link. The materials of making clothes often need high cost. In addition, customers put forward a request in the quality of clothes. Thus, choosing an optimal supplier is an essential part of job. Reaching cooperation with an optimal supplier not only can help garment manufacturer improve the quality of clothes but also is benefit to reduce the cost of producing. Most importantly, it can improve the competitiveness of manufacture enterprises. So, it is important for managers to find an optimal supplier and make a cooperation with it. In this paper, we analysis an issue about choosing an optimal supplier during four different suppliers. With analyzing this problem, we can introduce an extended method under picture fuzzy environment to evaluate and choose an optimal supplier. In this article, we describe some basic knowledges about picture fuzzy sets (PFSs) and picture fuzzy numbers (PFNs). Then, we introduce the extension of MABAC method which is on the basis of prospect theory (PT) with picture fuzzy numbers (PF-PT-MABAC) and utilize the PF-PT-MABAC model to evaluate different suppliers to choose an optimal supplier. Finally, we compare the result of PF-PT-MABAC with the result of traditional MABAC, PFWG operators and traditional TODIM method to test the efficiency of PF-PT-MABAC model.
A new method for ranking the usefulness of negative online reviews based on combined weighting method and improved TOPSIS
Authors: Yang Luting , Li Yan
Published: January 2022

Online shopping has gradually become an important way of consumption, and consumers are paying more and more attention to negative reviews. In order to avoid the massive amount of negative review information leading to loss of useful information, this paper proposes a method for evaluating the usefulness of negative online reviews. Firstly, the method constructs an evaluation index system for the usefulness of negative online reviews from three aspects: the form feature, text feature, and reviewer feature of negative reviews, and uses a combination weighting method based on fuzzy analytic hierarchy process (FAHP) and entropy method to determine the weight of each index. Secondly, the usefulness ranking results of negative online reviews are obtained through the improved TOPSIS method based on the combined weighting method. Finally, the empirical analysis of the proposed model is carried out by crawling the negative online reviews of JD.com Fresh Food platform, and the improved model is compared with the traditional TOPSIS model, which proves the feasibility and effectiveness of the model.
The cost-sensitive approximation of neighborhood rough sets and granular layer selection
Authors: Yang Jie , Luo Tian , Zeng Lijuan , Jin Xin
Published: January 2022

Neighborhood rough sets (NRS) are the extended model of the classical rough sets. The NRS describe the target concept by upper and lower neighborhood approximation boundaries. However, the method of approximately describing the uncertain target concept with existed neighborhood information granules is not given. To solve this problem, the cost-sensitive approximation model of the NRS is proposed in this paper, and its related properties are analyzed. To obtain the optimal approximation granular layer, the cost-sensitive progressive mechanism is proposed by considering user requirements. The case study shows that the reasonable granular layer and its approximation can be obtained under certain constraints, which is suitable for cost-sensitive application scenarios. The experimental results show that the advantage of the proposed approximation model, moreover, the decision cost of the NRS approximation model will monotonically decrease with granularity being finer.