bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnosis and Orthodontic Treatment of Obstructive Sleep Apnea Syndrome Children—A Systematic Review
Authors: Ferati Kenan , Bexheti-Ferati Arberesha , Palermo Andrea , Pezzolla Carmen , Trilli Irma , Sardano Roberta , Latini Giulia , Inchingolo Alessio Danilo , Inchingolo Angelo Michele , Malcangi Giuseppina , Inchingolo Francesco , Dipalma Gianna , Mancini Antonio
Published: January 2024

Obstructive sleep apnea syndrome (OSAS) is a respiratory illness that is associated with recurrent episodes of either partial or full obstruction of the upper airways, or apnea, among other sleep disorders. This study aims to analyze, through a literature review, whether orthodontic treatment can be a good treatment strategy for this type of disorder. We performed a database search on Scopus, Web of Science, and Pubmed with the keywords OSA(S) and orthodontics to select the papers under evaluation. The criteria for inclusion were articles related to OSA(S) children undergoing an orthodontic treatment and clinical studies or case series, excluding systematic reviews, narrative reviews, meta-analyses, adult studies, animal models, and in vitro studies. The screening phase ended with the selection of 16 publications for this work. RME, or rapid maxillary expansion, turned out to be the preferred orthodontic treatment in cases of pediatric OSAS. The goal of this orthodontic procedure is to increase the hard palate’s transverse diameter by reopening the mid-palatal suture. Children with maxillary contraction and dental malocclusion typically undergo such a procedure and have excellent results. However, OSAS is a multifactorial disorder; it does not seem related to the morphology of the oral cavity, and therefore, it is not always possible to cope with this problem exclusively through orthodontic treatment.
Exploring the Risk Factors for Oral Cancer in Pakistan: A Systematic Literature Review
Authors: Khan Muhammad Feroz , Hayhoe Richard P. , Kabir Russell
Published: January 2024

Background: Oral cancer is one of the major public health issues in Pakistan and is the second most common malignancy in the country. This is mainly attributed to the widespread use of smokeless tobacco products, cigarettes, and paan without tobacco. This review aims to go beyond commonly discussed factors and, consequently, to provide a comprehensive picture of all the multi-faceted contributors to the high prevalence of the carcinoma of the oral cavity, including the role of human papillomavirus and genetic predisposition. The aim is to synthesise all available evidence on the predisposing factors of oral carcinoma in Pakistan. Methods: This is a comprehensive systematic review of all observational studies investigating the contributing factors of malignancy of the oral cavity in Pakistan, and it strictly follows the PRISMA guidelines. Multiple databases, such as PubMed, EBSCO CINAHL Plus, SCOPUS, and Ovid Medline, were used to find studies, and the Cochrane Database of Systematic Reviews was searched for existing/ongoing reviews carried out on the same topic. A meta-synthesis of selected studies was carried out to create robust and statistically valid conclusions. Results: ST and cigarette smoking were found to be the major contributors to the burden of carcinoma of the lip and oral cavity. The included studies indicated that genetic predisposition and human papillomavirus could be major risk factors for the disease in the Pakistani population, but not enough research has been carried out to find their true impact. Conclusions: Smokeless tobacco, cigarette smoking, genetic predisposition, and human papillomavirus can be considered significant risk factors for oral cancer in Pakistan.
Lossy Compression of Individual Sequences Revisited: Fundamental Limits of Finite-State Encoders
Authors: Merhav Neri
Published: January 2024

We extend Ziv and Lempel’s model of finite-state encoders to the realm of lossy compression of individual sequences. In particular, the model of the encoder includes a finite-state reconstruction codebook followed by an information lossless finite-state encoder that compresses the reconstruction codeword with no additional distortion. We first derive two different lower bounds to the compression ratio, which depend on the number of states of the lossless encoder. Both bounds are asymptotically achievable by conceptually simple coding schemes. We then show that when the number of states of the lossless encoder is large enough in terms of the reconstruction block length, the performance can be improved, sometimes significantly so. In particular, the improved performance is achievable using a random-coding ensemble that is universal, not only in terms of the source sequence but also in terms of the distortion measure.
Computational Thinking (CT) towards Creative Action: Developing a Project-Based Instructional Taxonomy (PBIT) in AI Education
Authors: Zhou Chunfang , Zhang Wei
Published: January 2024

This paper aims to develop a new model of Project-Based Instructional Taxonomy (PBIT) that provides a tool of course design that facilitates Computational Thinking (CT) development as creative action in solving real-life problems. Theoretically, PBIT is built on an integrative framework bringing together with studies on CT education, creativity, Bloom’s Taxonomy, and Project-Based Instruction (PBI). This guides the course design to make alignment between diverse elements including education objectives, categories of CT, levels of learning ability, process of project facilitation, and methods of grading. A case will be discussed that focuses on a course Deep Learning and Technologies in AI bachelor program at Northeastern University (NEU) in China. It also shows how PBIT is applied in teaching practice that benefits students’ CT development. As the conclusion indicates, this paper has contributions to future research on creativity, PBI, CT, and AI education.
Ignition Locations and Simplified Design Guidelines for Enhancing the Resilience of Dwellings against Wildland Fires
Authors: Arruda Mário Rui Tiago , Bicelli António Renato A. , Branco Fernando
Published: January 2024

This paper presents a study based on new fireproof design guidelines for dwellings against the impact of wildfires. The main objective is to present the results from the surveys of the large wildfires of 2017 in Portugal, identifying vulnerabilities in dwellings that may result in spot ignitions when exposed to wildfires. Utilizing the information gathered from these surveys, it is possible to recommend fire resistance and reaction class requirements using European indoor fire standards and adapting them to suit wildfire conditions. The study focuses on classical dwellings predominantly located in high-risk fire zones within the wildland–urban interface. These assessments have the potential to generate new fireproof construction recommendations employing traditional materials commonly found in the European construction industry.
In Vitro Culture of Glochidia and Morphological Changes in Juveniles of the Endangered Freshwater Mussel Solenaia oleivora
Authors: Ma Xueyan , Jin Wu , Lv Guohua , Chen Wanwen , Xu Dongpo , Xu Pao , Hua Dan , Wen Haibo
Published: January 2024

The artificial propagation of the endangered Solenaia oleivora, with unknown fish hosts, was performed via in vitro culture with bighead carp, grass carp, common carp, bovine, and rabbit sera. The effects of glochidium density on transformation rates were evaluated, and the development of juveniles that metamorphosed successfully was documented. The control group had a transformation rate of 0 and a contamination rate of 0. No significant differences were found in the transformation and contamination rates of the bighead carp, grass carp, and common carp serum groups, and their transformation rates were significantly higher, and contamination rates were significantly lower than those of the bovine and rabbit serum groups. Moreover, no significant differences were observed in the transformation rates of glochidia (culture density, 2000–5000 glochidia/dish) in contamination-free conditions. Specimen shell length/height increased from 1.08 ± 0.01 on the first day to 3.08 ± 0.29 during the 13th week. On the basis of anterior and posterior growth differences, juvenile growth was divided into the following three phases: the rapid anterior growth period, distinct anterior and posterior idiophase, and rapid posterior growth period. This study not only provides technological support for the artificial propagation of S. oleivora but also lays a foundation for resource recovery.
Application of Central-Weighted Essentially Non-Oscillatory Finite-Volume Interface-Capturing Schemes for Modeling Cavitation Induced by an Underwater Explosion
Authors: Adebayo Ebenezer Mayowa , Tsoutsanis Panagiotis , Jenkins Karl W.
Published: January 2024

Cavitation resulting from underwater explosions in compressible multiphase or multicomponent flows presents significant challenges due to the dynamic nature of shock–cavitation–structure interactions, as well as the complex and discontinuous nature of the involved interfaces. Achieving accurate resolution of interfaces between different phases or components, in the presence of shocks, cavitating regions, and structural interactions, is crucial for modeling such problems. Furthermore, pressure convergence in simulations involving shock–cavitation–structure interactions requires accurate algorithms. In this research paper, we employ the diffuse interface method, also known as the interface-capturing scheme, to investigate cavitation in various underwater explosion test cases near different surfaces: a free surface and a rigid surface. The simulations are conducted using the unstructured compressible Navier–Stokes (UCNS3D) finite-volume framework employing central-weighted essentially non-oscillatory (CWENO) reconstruction schemes, utilizing the five-equation diffuse interface family of methods. Quantitative comparisons are made between the performance of both models. Additionally, we examine the effects of cavitation as a secondary loading source on structures, and evaluate the ability of the CWENO schemes to accurately capture and resolve material interfaces between fluids with minimal numerical dissipation or smearing. The results are compared with existing high-order methods and experimental data, where possible, to demonstrate the robustness of the CWENO schemes in simulating cavitation bubble dynamics, as well as their limitations within the current implementation of interface capturing.
Evaluation of the Potential Protective Effect of Ellagic Acid against Heavy Metal (Cadmium, Mercury, and Lead) Toxicity in SH-SY5Y Neuroblastoma Cells
Authors: Mallamaci Rosanna , Barbarossa Alexia , Carocci Alessia , Meleleo Daniela
Published: January 2024

Ellagic acid (EA), a polyphenolic constituent of plant origin, has been thoroughly investigated for its hypothesised pharmacological properties among which antioxidant and neuroprotective activities are included. The present study was designed to explore whether EA could attenuate heavy metal (cadmium, mercury, and lead)-induced neurotoxicity in SH-SY5Y cells, which were utilized as a model system for brain cells. MTT and LDH assays were performed to examine the viability of the SH-SY5Y cells after exposure to Cd, Hg, and Pb (either individually or in combination with EA) as well as the effects of necrotic cell death, respectively. Furthermore, 2′,7′-dichlorodihydrofluorescein diacetate (DCFH-DA), a cell-based assay, was performed to determine whether EA could protect SH-SY5Y from heavy metal-induced oxidative stress. Results allowed us to assess the capability of EA to enhance the number of viable SH-SY5Y cells after exposure to heavy metal toxicity. Pre-treatment with EA showed a considerable, concentration-dependent, cytoprotective effect, particularly against Cd2+-induced toxicity. This effect was confirmed through the reduction of LDH release after the simultaneous cell treatment with Cd2+ and EA compared with Cd2+-treated cells. Furthermore, a significant, concentration-dependent decrease in reactive oxygen species (ROS) production, induced by H2O2 or heavy metals, was observed in the same model. Overall, the obtained results provide further insight into the protective role of EA against heavy metal-induced neurotoxicity and oxidative stress, thus indicating the potential beneficial effects of the consumption of EA-rich foods. However, to confirm its effects, well-designed human randomized controlled trials are needed to fill the existing gap between experimental and clinical research.
Immobilization of Enological Pectinase on Magnetic Sensitive Polyamide Microparticles for Wine Clarification
Authors: Oliveira Sandra Cristina , Dencheva Nadya Vasileva , Denchev Zlatan Zlatev
Published: January 2024

The use of free pectinases as clarification biocatalysts constitutes a well-established practice in the large-scale production of various types of wines. However, when in the form of free enzymes, the recovery and reusability of pectinases is difficult if not impossible. To address these limitations, the present study focuses on the noncovalent adsorption immobilization of a commercial pectinolytic preparation onto highly porous polyamide 6 (PA6) microparticles, both with and without magnetic properties, prepared via activated anionic polymerization. The two pectinase complexes resulting after immobilization underwent comparative activity and kinetic studies, contrasting them with the free enzyme preparation. In comparison with the free enzyme, the PA6-immobilized pectinase complexes exhibited more than double the specific activity toward the pectin substrate. They displayed a slightly higher affinity to the substrate while acting as faster catalysts that were more resistant to inhibition. Furthermore, the immobilized complexes were applied in the clarification process of industrial rosé must, whereby they demonstrated accelerated performance as compared with the free enzyme. Moreover, the PA6-immobilized pectinase biocatalysts offered the potential for three consecutive cycles of reuse, achieving complete rosé must clarification within relevant timeframes in the range of 3–36 h. All these results suggest the potential industrial application of the pectinases noncovalently immobilized upon PA6 microparticles.
Non-Destructive Assessment of Microstructural Changes in Kabuli Chickpeas during Storage
Authors: Indore Navnath S. , Chaudhry Mudassir , Jayas Digvir S. , Paliwal Jitendra , Karunakaran Chithra
Published: January 2024

The potential of hyperspectral imaging (HSI) and synchrotron phase-contrast micro computed tomography (SR-µCT) was evaluated to determine changes in chickpea quality during storage. Chickpea samples were stored for 16 wk at different combinations of moisture contents (MC of 9%, 11%, 13%, and 15% wet basis) and temperatures (10 °C, 20 °C, and 30 °C). Hyperspectral imaging was utilized to investigate the overall quality deterioration, and SR-µCT was used to study the microstructural changes during storage. Principal component analysis (PCA) and Partial Least Squares Discriminant Analysis (PLS-DA) were used as multivariate data analysis approaches for HSI data. Principal component analysis successfully grouped the samples based on relative humidity (RH) and storage temperatures, and the PLS-DA classification also resulted in reliable accuracy (between 80 and 99%) for RH-based and temperature-based classification. The SR-µCT results revealed that microstructural changes in kernels (9% and 15% MC) were dominant at higher temperatures (above 20 °C) as compared to lower temperatures (10 °C) during storage due to accelerated spoilage at higher temperatures (above 20 °C). Chickpeas which had internal irregularities like cracked endosperm and air spaces before storage were spoiled at lower moisture from 8 wk of storage.
Encapsulation of Benzaldehyde Produced by the Eco-Friendly Degradation of Amygdalin in the Apricot Kernel Debitterizing Wastewater
Authors: Song Lei , García Martín Juan Francisco , Zhang Qing-An
Published: January 2024

In order to fully utilize the by-products of apricot kernel-debitterizing and address the chemical instability of benzaldehyde in the food industry, benzaldehyde was first prepared by adding the apricot kernel powder to degrade the amygdalin present in the apricot kernel-debitterizing water. Subsequently, β-cyclodextrin was employed to encapsulate the benzaldehyde, and its encapsulation efficacy was evaluated through various techniques including Fourier transform infrared spectroscopy, thermogravimetric analysis, release kinetics fitting inhibitory effect and the effect on Botrytis cinerea. Finally, the encapsulation was explored via molecular docking and molecular dynamics simulations. The results indicate that the optimal preparation conditions for the benzaldehyde were 1.8 h, 53 °C and pH 5.8, and the encapsulation of benzaldehyde with β-cyclodextrin (wall–core ratio of 5:1, mL/g) has been verified by the deceleration in the release rate, the enhanced thermal stability and the prolonged inhibition effect against Botrytis cinerea. The encapsulation proceeded spontaneously without steric hindrance in the simulation, which led to a reduction in the hydrophobic cavity of β-cyclodextrin. In conclusion, the amygdalin in the debitterizing wastewater can be degraded in an eco-friendly way to produce benzaldehyde by adding apricot kernel powder, which contains β-glucosidase; the encapsulation of benzaldehyde is stable, thus enhancing the utilization of amygdalin in the debitterizing wastewater of apricot kernels.
NaDES Application in Cosmetic and Pharmaceutical Fields: An Overview
Authors: Villa Carla , Caviglia Debora , Robustelli della Cuna Francesco Saverio , Zuccari Guendalina , Russo Eleonora
Published: January 2024

Natural deep eutectic solvents (NaDES) represent a new generation of green, non-flammable solvents, useful as an efficient alternative to the well-known ionic liquids. They can be easily prepared and exhibit unexpected solubilizing power for lipophilic molecules, although those of a hydrophilic nature are mostly used. For their unique properties, they can be recommend for different cosmetic and pharmaceutical applications, ranging from sustainable extraction, obtaining ready-to-use ingredients, to the development of biocompatible drug delivery responsive systems. In the biomedical field, NaDES can be used as biopolymer modifiers, acting as delivery compounds also known as “therapeutic deep eutectic systems”, being able to solubilize and stabilize different chemical and galenical formulations. The aim of this review is to give an overview of the current knowledge regarding natural deep eutectic solvents specifically applied in the cosmetic and pharmaceutical fields. The work could help to disclose new opportunities and challenges for their implementation not only as green alternative solvents but also as potential useful pathways to deliver bioactive ingredients in innovative formulations.
The Recent Progress of the Cellulose-Based Antibacterial Hydrogel
Authors: Sun Ying , Wang Jiayi , Li Duanxin , Cheng Feng
Published: January 2024

Cellulose-based antibacterial hydrogel has good biocompatibility, antibacterial performance, biodegradability, and other characteristics. It can be very compatible with human tissues and degradation, while its good water absorption and moisturizing properties can effectively absorb wound exudates, keep the wound moist, and promote wound healing. In this paper, the structural properties, and physical and chemical cross-linking preparation methods of cellulose-based antibacterial hydrogels were discussed in detail, and the application of cellulose-based hydrogels in the antibacterial field was deeply studied. In general, cellulose-based antibacterial hydrogels, as a new type of biomaterial, have shown good potential in antimicrobial properties and have been widely used. However, there are still some challenges, such as optimizing the preparation process and performance parameters, improving the antibacterial and physical properties, broadening the application range, and evaluating safety. However, with the deepening of research and technological progress, it is believed that cellulose-based antibacterial hydrogels will be applied and developed in more fields in the future.
How Did the Late Paleozoic to Early Mesozoic Tectonism Constrain the Carboniferous Stratigraphic Evolution in the Eastern Qaidam Basin, NW China?
Authors: Zhong Chang , Tang Xiaoyin , Wang Jiaqi
Published: January 2024

The eastern Qaidam Basin (EQB), along with its surrounding orogenic belts, witnessed complicated tectonic movements in the period from the late Paleozoic to the early Mesozoic. As strategic succeeding strata, the Carboniferous strata (CST) in the EQB have gradually become a research hotspot in recent years. However, the question of how tectonism controlled the tempo-spatial evolution of the CST has yet to be studied. To resolve these issues, we collated statistics related to unconformities, seismic interpretation, and basin modeling in this study. The results show that the structure of the CST was mostly controlled by NNE-striking faults, namely the Zongjia and Ainan Fault, in the period from the Carboniferous to the Triassic time. During the Carboniferous time, the sedimentation of the CST was controlled by medium-high angle potential normal faults. The CST experienced two stages of tectonic subsidence and subsequent burial: the highest average subsidence and burial rate of 45 m/Ma and 12 m/Ma occurred at 340~285 Ma, decreasing to 15 m/Ma and 7.5 m/Ma between 305 Ma and 250 Ma. However, the maximum burial (~5500 m) took place at ~250 Ma. From the end of the late Permian to the late Triassic (254~195 Ma), the overall exhumation rate of the CST has averaged 38.71 m/Ma, and 75 m/Ma in the southern margin of the Huobuxun Depression. The CST near the piedmont margins of the EQB suffered essential denudation at 254~195 Ma, resulting in small amounts of the residual CST. In these areas, the CST were deformed with a steepening dip during this time and were characterized by the combinations of syncline-anticlinal asymmetric folds with the high-angle interlimb. These findings indicated that the tempo-spatial evolution of the CST was possibly influenced by the sedimentary and tectonic transition, and was a combined response to Paleo-Tethys Ocean subduction, and arc-continental collisions since the late Paleozoic to early Mesozoic periods.
Investigating the Electrical and Mechanical Properties of Polystyrene (PS)/Untreated SWCNT Nanocomposite Films
Authors: Parnian Pooyan , D’Amore Alberto
Published: January 2024

This paper presents a study of the electrical and mechanical properties of polystyrene (PS)/carbon nanotube (CNT) composites prepared using the doctor blade technique. The nanocomposite films of PS/CNT were prepared by casting a composite solution of PS/CNT in tetrahydrofuran (THF) on a glass substrate using a doctor blade and drying in an oven. The nanocomposite films were then characterized using a tensile test and the four-point probe method to evaluate their mechanical properties and electrical conductivity. The experimental results were used to analyze the unpredicted behavior of the nanocomposite films. The experimental results showed that the electrical conductivity of the nanocomposite films became almost insensitive or unmeasurable with increasing CNT content for very dilute PS–THF solutions. In contrast, at higher PS concentrations, film conductivity increased to a given CNT threshold and then decreased. Based on PS–THF viscosity–concentration data, a discussion is elaborated that partially justifies the experimental results.
The Use of Functional Biomaterials in Aesthetic and Functional Restoration in Orbital Surgery
Authors: Wu Kevin Y. , Fujioka Jamie K. , Daigle Patrick , Tran Simon D.
Published: January 2024

The integration of functional biomaterials in oculoplastic and orbital surgery is a pivotal area where material science and clinical practice converge. This review, encompassing primary research from 2015 to 2023, delves into the use of biomaterials in two key areas: the reconstruction of orbital floor fractures and the development of implants and prostheses for anophthalmic sockets post-eye removal. The discussion begins with an analysis of orbital floor injuries, including their pathophysiology and treatment modalities. It is noted that titanium mesh remains the gold standard for orbital floor repair due to its effectiveness. The review then examines the array of materials used for orbital implants and prostheses, highlighting the dependence on surgeon preference and experience, as there are currently no definitive guidelines. While recent innovations in biomaterials show promise, the review underscores the need for more clinical data before these new materials can be widely adopted in clinical settings. The review advocates for an interdisciplinary approach in orbital surgery, emphasizing patient-centered care and the potential of biomaterials to significantly enhance patient outcomes.
Correction: Bolocan et al. Convolutional Neural Network Model for Segmentation and Classification of Clear Cell Renal Cell Carcinoma Based on Multiphase CT Images. J. Imaging 2023, 9, 280
Authors: Bolocan Vlad-Octavian , Secareanu Mihaela , Sava Elena , Medar Cosmin , Manolescu Loredana Sabina Cornelia , Rașcu Alexandru-Ștefan Cătălin , Costache Maria Glencora , Radavoi George Daniel , Dobran Robert-Andrei , Jinga Viorel
Published: January 2024

In the original publication [...]
The Reality of a Head-Mounted Display (HMD) Environment Tested via Lightness Perception
Authors: Kuriki Ichiro , Sato Kazuki , Shioiri Satoshi
Published: January 2024

Head-mounted displays (HMDs) are becoming more and more popular as a device for displaying a virtual reality space, but how real are they? The present study attempted to quantitatively evaluate the degree of reality achieved with HMDs by using a perceptual phenomenon as a measure. Lightness constancy is an ability that is present in human visual perception, in which the perceived reflectance (i.e., the lightness) of objects appears to stay constant across illuminant changes. Studies on color/lightness constancy in humans have shown that the degree of constancy is high, in general, when real objects are used as stimuli. We asked participants to make lightness matches between two virtual environments with different illuminant intensities, as presented in an HMD. The participants’ matches showed a high degree of lightness constancy in the HMD; our results marked no less than 74.2% (84.8% at the maximum) in terms of the constancy index, whereas the average score on the computer screen was around 65%. The effect of head-tracking ability was confirmed by disabling that function, and the result showed a significant drop in the constancy index but that it was equally effective when the virtual environment was generated by replay motions. HMDs yield a realistic environment, with the extension of the visual scene being accompanied by head motions.
A New Plastic Design Approach for the Vertical-Side-Plating Thickness of Ice-Strengthened Ships Suffering from Ice Floe Impacts
Authors: Mu Mengying , Guo Kailing , Cai Wei , Zhu Ling , Pi Zhenyu , Zhou Shuo
Published: January 2024

Ice-strengthened ships inevitably suffer from ice floe impacts during navigation in icy regions. Under some extreme-ice-impact loadings, the ship structure will experience plastic deformations. The magnitude of plastic deformation is highly correlated with the ice floe-impact energy level. During most ice impacts, only the ship’s plate undergoes minor plastic deformation. Considering that the structure still has a high structural strength with a minor permanent deformation, developing a structural plastic design method for polar ships has become a hot research issue in current studies. Therefore, in this paper, based on the rigid-plastic theory and the ice-crushing-energy approach, an experimentally verified theoretical model for predicting plastic deformations of the vertical-side plate of polar ship subjected to ice floe impacts was established. According to the analytical solutions of the plastic deformation, the plastic design formula to determine the plating thickness of ice-strengthened ships subjected to ice floe impacts was further derived based on the plastic design criteria. In addition, the parameter analysis of ice strength described by the ice pressure–area relationship, allowable-permanent-set parameter, impact energy and ice shape were conducted, and plating-thickness design curves with different design parameters were given. The design of plating thickness is very sensitive to the determinations of the allowable-permanent set and ice pressure–area curves. The designed plating thickness decreased with the increase of the allowable-permanent set. Moreover, a comparative analysis of the designed plating thickness for ice floe impact and rigid-mass impact was also carried out. Under the same impact conditions, due to energy absorption caused by ice damage, the designed thickness of the plate for rigid-mass impact was much larger than that for the ice impact. It is necessary to consider the impact-induced ice damage and energy dissipation in a structural design, instead of using rigid impact loads for conservative design. The research in this paper can provide some useful references for the structural design of ice-strengthened ships subject to ice floe impacts.
Development of Biological Risk Assessment Protocols for Evaluating the Risks of In-Water Cleaning of Hull-Fouling Organisms
Authors: Hyun Bonggil , Jang Pung-Guk , Jang Min-Chul , Kang Jung-Hoon , Kim Ju-Hyoung , Ki Jang-Seu , Choi Dong Han , Yu Ok Hwan , Seo Jin-Young , Lee Woo-Jin , Shin Kyoungsoon
Published: January 2024

Herein, we evaluate the scientific basis for managing hull fouling of ships entering Korean ports, diagnose biological risks that may occur when in-water cleaning (IWC) systems remove hull fouling, and present a protocol for evaluating these risks (the Korean Infection Modes and Effects Analysis; K-IMEA). Protocol development included the selection of core elements and scenario design for IWC and the evaluation of regrowth experiments. The K-IMEA index was designed by considering the inoculation pathway of attaching organisms in all processes to ships that enter a port for in-water cleaning. A number of risk indices were defined: R1—Introduction/Establishment of alien species before in-water cleaning; R2—Establishment of alien species escaped during in-water cleaning; R3—Introduction/Establishment of alien species after in-water cleaning; and R4—Establishment of alien species in effluent water. K-IMEA regrowth experiments (R2 and R4) using the in-water cleaning effluent showed that the attachment and regrowth of prokaryotes, microalgae, and macroalgae were successfully detected. In particular, prokaryotes were observed in samples filtered through a 5 μm mesh of the in-water cleaning effluent, even at a low fouling rating (Levels 1–2). These experiments suggest a necessity to consider a secondary treatment method in addition to the primary filtration method for the treatment of in-water cleaning effluents.
Scaled Conjugate Gradient Neural Intelligence for Motion Parameters Prediction of Markov Chain Underwater Maneuvering Target
Authors: Ali Wasiq , Zuberi Habib Hussain , Qing Xin , Miyajan Abdulaziz , Jaffar Amar , Alharbi Ayman
Published: January 2024

This study proposes a novel application of neural computing based on deep learning for the real-time prediction of motion parameters for underwater maneuvering object. The intelligent strategy utilizes the capabilities of Scaled Conjugate Gradient Neural Intelligence (SCGNI) to estimate the dynamics of underwater target that adhere to discrete-time Markov chain. Following a state-space methodology in which target dynamics are combined with noisy passive bearings, nonlinear probabilistic computational algorithms are frequently used for motion parameters prediction applications in underwater acoustics. The precision and robustness of SCGNI are examined here for effective motion parameter prediction of a highly dynamic Markov chain underwater passive vehicle. For investigating the effectiveness of the soft computing strategy, a steady supervised maneuvering route of undersea passive object is designed. In the framework of bearings-only tracking technology, system modeling for parameters prediction is built, and the effectiveness of the SCGNI is examined in ideal and cluttered marine atmospheres simultaneously. The real-time location, velocity, and turn rate of dynamic target are analyzed for five distinct scenarios by varying the standard deviation of white Gaussian observed noise in the context of mean square error (MSE) between real and estimated values. For the given motion parameters prediction problem, sufficient Monte Carlo simulation results support SCGNI’s superiority over typical generalized pseudo-Bayesian filtering strategies such as Interacting Multiple Model Extended Kalman Filter (IMMEKF) and Interacting Multiple Model Unscented Kalman Filter (IMMUKF).
Parasitism-Induced Changes in Microbial Eukaryotes of Peruvian Alpaca Gastrointestinal Tract
Authors: Sanchez Diana , Zapata Celso , Romero Yolanda , Flores-Huarco Nils H. , Oros Oscar , Alvarado Wigoberto , Quilcate Carlos , Guevara-Alvarado Hada M. , Estrada Richard , Coila Pedro
Published: January 2024

Alpacas, important genetic resources in the Andean region of Peru, are vulnerable to diarrhea caused by pathogenic parasites such as Eimeria lamae and Giardia sp., which can be fatal, especially in neonates, due to their physiological immaturity and limited adaptability. The study investigated the diversity and abundance of intestinal fungi and protists in alpacas infected with Eimeria lamae and Giardia sp. compared to healthy alpacas. A total of 19 alpacas, aged between one and two months, were included. They were divided into two groups, one with pathological conditions (nine) and the other healthy (ten). Parasitological analyses for the detection of parasites and subsequent molecular analysis were performed on the collected fecal samples. The results revealed a greater diversity and abundance of protists in infected alpacas in comparison with healthy alpacas, while the fungal composition did not show significant changes. Therefore, parasitic infections affect the protist component of the alpaca gut microbiota. Also, it was observed that Blastocystis was identified in all healthy alpacas, serving as a possible marker of the health of the intestinal microbiota; in addition, Prussia and Pichia are beneficial fungi that help control diseases. This groundbreaking study in neonatal alpacas is the first to explore potential changes in the intestinal microbiota during an infectious state, underscoring the importance of further research to comprehend its effects on alpaca health and immune responses.
The Association between Abstinence Period and Semen Parameters in Humans: Results in Normal Samples and Different Sperm Pathology
Authors: Xie Min , Hämmerli Silvan , Leeners Brigitte
Published: January 2024

Background: The impact of sexual abstinence on sperm quality, particularly in pathological cases, is a subject of debate. We investigated the link between abstinence duration and semen quality in both normal and pathological samples. Methods: We analyzed semen samples from 4423 men undergoing fertility evaluation, comprising 1256 samples from healthy individuals and 3167 from those with conditions such as oligozoospermia, asthenozoospermia, teratozoospermia, or a combination of these factors, namely oligoasthenoteratozoospermia (OAT). Parameters including sperm concentration, the percentage of progressively motile spermatozoa, total motile sperm count, and the percentage of spermatozoa with normal morphology were assessed at various abstinence durations (each day, 0–2, 3–7, and >7 days). Results: Extended abstinence correlated with higher sperm concentration overall (p < 0.001), except in oligozoospermia. Longer abstinence reduced progressive motility in normal (p < 0.001) and teratozoospermic samples (p < 0.001). Shorter abstinence was linked to higher morphologically normal sperm in normal samples (p = 0.03), while longer abstinence did so in oligoasthenoteratozoospermic samples (p = 0.013). Conclusion: The findings suggest that a prolonged abstinence time is linked to higher sperm concentration, while optimal sperm motility is observed after shorter abstinence periods. However, results regarding morphology remain inconclusive. Recommendations on abstinence duration should be tailored based on the specific parameter requiring the most significant improvement.
The Sequence Characteristics and Binding Properties of the Odorant-Binding Protein SvelOBP1 from Sympiezomias velatus (Coleoptera: Curculionidae) to Jujube Volatiles
Authors: Zhai Yingyan , Zhang Feng , Tian Tianqi , Yang Yiwei , Li Yang , Ren Bowen , Hong Bo
Published: January 2024

Sympiezomias velatus (Chevrolat) (Coleoptera: Curculionidae) has caused serious damage on jujube trees (Ziziphus jujuba Mill) in northern China. Semiochemicals emerging from the host are essential in the process of insects identifying and localizing the host. The highly expressed odorant-binding protein 1 of S. velatus (SvelOBP1) was assumed to play a possible role in the recognition of host volatiles. In this study, SvelOBP1 was cloned based on the antennal transcriptome of S. velatus. The recombinant SvelOBP1 protein was expressed in Escherichia coli and purified by Ni-NTA resin. The predicted protein SvelOBP1 belonged to a classic OBP subfamily. The expression patterns revealed that SvelOBP1 was mainly expressed in the antennae of both males and females, whereas the expression of SvelOBP1 in other body parts could be neglected. The fluorescence binding assay indicated that SvelOBP1 displayed very strong binding affinities to dibutyl benzene-1,2-dicarboxylate and (Z)-hex-3-en-1-ol (Ki = 6.66 ± 0.03 and 7.98 ± 0.06 μM). The molecular docking results showed that residues Trp114, Phe115 and Asp110 may be involved in binding to both dibutyl benzene-1,2-dicarboxylate and (Z)-hex-3-en-1-ol and may have a great impact on odorant recognition of S. velatus. Our results provide evidence that SvelOBP1 might participate in the olfactory molecular perception of S. velatus and would promote the development of pest attractants for S. velatus control.
Chronic Toxoplasma gondii Infection Modulates Hearing Ability across the Adult Life Span
Authors: Getzmann Stephan , Golka Klaus , Bröde Peter , Reinders Jörg , Kadhum Thura , Hengstler Jan G. , Wascher Edmund , Gajewski Patrick D.
Published: January 2024

While several studies have shown associations between hearing disorders and congenital toxoplasmosis, the present study investigated the impact of chronic, latent Toxoplasma gondii (T. gondii) infection on hearing loss. We used a regression analysis to explore whether latent T. gondii infection modulates changes in hearing thresholds over an age range from 20 to 70 years. We analyzed audiometric data of 162 T. gondii IgG-positive and 430 T. gondii-negative participants, collected in the Dortmund Vital Study (DVS, ClinicalTrials.gov Identifier: NCT05155397), a prospective study on healthy cognitive aging. The regression analysis indicated that latent toxoplasmosis was associated with an accelerated development in hearing loss over the observed age range. Hearing loss was less frequent in IgG-positive than in IgG-negative participants up to the age of about 40 for a low (0.125–1 kHz)-frequency range. For high (2–8 kHz) frequencies, this pattern reversed for ages above 65 years. We discuss these findings on hearing function in the context of a recently proposed model, suggesting that latent toxoplasmosis can differentially affect brain functions across a lifespan.
Transient Simulation Analysis of Needle Roller Bearing in Oil Jet Lubrication and Planetary Gearbox Lubrication Conditions Based on Computational Fluid Dynamics
Authors: Gao Shushen , Hou Xiangying , Ma Chenfei , Yang Yankun , Li Zhengminqing , Yin Rui , Zhu Rupeng
Published: January 2024

The transient lubrication conditions of rolling bearings are different in gearboxes and bearing testers. It has been observed that samples of qualified rolling bearings tested in rolling bearing testers often fail and do not meet lifespan requirements when employed in other lubrication conditions. This may be caused by different factors affecting the bearing in testing and applying lubrication. Needle roller bearings were selected for this study to investigate the causes of this phenomenon in terms of lubrication. Based on the computational fluid dynamics (CFD) method, fluid domain models for the same type of rolling bearings with different lubrication conditions were established. The transient flow fields of rolling bearings with oil jet lubrication in a tester and splash lubrication in a planetary gearbox were simulated. The air–oil transient distribution of rolling bearings in two kinds of lubrication was analyzed. The results indicate that the rotational speed significantly affected the oil jet lubrication of the needle roller bearing. The average oil volume fraction rose by 0.2 with the increase in the bearing speed from 1200 r/min to 6000 r/min and by 0.06 with the increase in the oil jet velocity from 8 m/s to 16 m/s. The splash lubrication of the bearings in the planetary gearbox was directly related to the immersion depth of the rolling bearings in the initial position. Meanwhile, the splash lubrication of the bearings was also affected by other factors, including the initial layout of the planetary gears. The increase in speed from 1200 r/min to 6000 r/min made the average oil volume fraction of splash lubrication decrease by 4.4%. The average oil volume fraction of the bearings with splash lubrication was better than that with oil jet lubrication by an average of 41.9% when the bearing speed was in the low-speed stage, ranging from 1200 r/min to 3600 r/min. On the contrary, the bearings with oil jet lubrication were better than those with splash lubrication by an average of 31.8% when the bearing speed was in the high-speed stage, ranging from 4800 r/min to 6000 r/min.
Simulation of a Combined (2+1)-Dimensional Potential Kadomtsev–Petviashvili Equation via Two Different Methods
Authors: Awadalla Muath , Akbulut Arzu , Alahmadi Jihan
Published: January 2024

This paper presents an investigation into original analytical solutions of the (2+1)-dimensional combined potential Kadomtsev–Petviashvili and B-type Kadomtsev–Petviashvili equations. For this purpose, the generalized Kudryashov technique (GKT) and exponential rational function technique (ERFT) have been applied to deal with the equation. These two methods have been applied to the model for the first time, and the the generalized Kudryashov method has an important place in the literature. The characteristics of solitons are unveiled through the use of three-dimensional, two-dimensional, contour, and density plots. Furthermore, we conducted a stability analysis on the acquired results. The results obtained in the article were seen to be different compared to other results in the literature and have not been published anywhere before.
Sensitivity Analysis, Synthesis and Gait Classification of Reconfigurable Klann Legged Mechanism
Authors: Hayat Abdullah Aamir , Megalingam Rajesh Kannan , Kumar Devisetty Vijay , Rudravaram Gaurav , Nansai Shunsuke , Elara Mohan Rajesh
Published: January 2024

Legged locomotion is essential for navigating challenging terrains where conventional robotic systems encounter difficulties. This study investigates the sensitivity of the reconfigurable Klann legged mechanism (KLM) to variations in the input geometric parameters, such as joint position location, link lengths, and angles between linkages, on the continuous coupler curve, which represents the output trace of the leg movement.The continuous coupler curve’s sensitivity is explored using global sensitivity analysis based on Sobol’s sensitivity method. Furthermore, a novel reconfigurability strategy is presented for the Klann mechanism, aiming to reduce the number of required actuators and the complexity in control. In simulation, the coupler curves obtained from the reconfigurable KLM are classified as hammering, digging, jam avoidance, and step climbing using machine learning approaches. Experimental validation is presented, discussing an approach to identifying geometric parameters and the resultant coupler curve. Illustrations of the the complete assembly of the reconfigured KLM with the obtained gaits using limited experiments are also highlighted.
A Comprehensive Multi-Strategy Enhanced Biogeography-Based Optimization Algorithm for High-Dimensional Optimization and Engineering Design Problems
Authors: Gao Chenyang , Li Teng , Gao Yuelin , Zhang Ziyu
Published: January 2024

The biogeography-based optimization (BBO) algorithm is known for its simplicity and low computational overhead, but it often struggles with falling into local optima and slow convergence speed. Against this background, this work presents a multi-strategy enhanced BBO variant, named MSBBO. Firstly, the example chasing strategy is proposed to eliminate the destruction of the inferior solutions to superior solutions. Secondly, the heuristic crossover strategy is designed to enhance the search ability of the population. Finally, the prey search–attack strategy is used to balance the exploration and exploitation. To verify the performance of MSBBO, we compare it with standard BBO, seven BBO variants (PRBBO, BBOSB, HGBBO, FABBO, BLEHO, MPBBO and BBOIMAM) and seven meta-heuristic algorithms (GWO, WOA, SSA, ChOA, MPA, GJO and BWO) on multiple dimensions of 24 benchmark functions. It concludes that MSBBO significantly outperforms all competitors both on convergence accuracy, speed and stability, and MSBBO basically converges to the same results on 10,000 dimensions as on 1000 dimensions. Further, MSBBO is applied to six real-world engineering design problems. The experimental results show that our work is still more competitive than other latest optimization techniques (COA, EDO, OMA, SHO and SCSO) on constrained optimization problems.
Free Vibration Analysis of Porous Functionally Graded Material Plates with Variable Thickness on an Elastic Foundation Using the R-Functions Method
Authors: Kurpa Lidiya , Pellicano Francesco , Shmatko Tetyana , Zippo Antonio
Published: January 2024

Free vibrations of porous functionally graded material (FGM) plates with complex shapes are analyzed by using the R-functions method. The thickness of the plate is variable in the direction of one of the axes. Two types of porosity distributions through the thickness are considered: uniform (even) and non-uniform (uneven). The elastic foundation is defined by two parameters (Winkler and Pasternak). To obtain the mathematical model of the problem, the first-order shear deformation theory of the plate (FSDT) is used. The effective material properties in the thickness direction are modeled by means of a power law. Variational Ritz’s method joined with the R-functions theory is used for obtaining a semi-analytical solution of the problem. The approach is applied to a number of case studies and validated by means of comparative analyses carried out on rectangular plates with a traditional finite element approach. The proof of the efficiency of the approach and its capability to handle actual engineering problems is fulfilled for FGM plates having complex shapes and various boundary conditions. The effect of different parameters, such as porosity distribution, volume fraction index, elastic foundation, FGM types, and boundary conditions, on the vibrations is studied.