bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Trunk Muscle Endurance in Chronic Ankle Instability
Authors: Noha Mahmoud Youssef  , Hossam Eddein Fawaz  , Ahmed Salamah Yamany  , Azza Mohammed Abdelmohsen  , Ghada Mohamed Elhafez
Published: November 2023

Background: Testing the association between trunk muscle endurance and chronic ankle instability (CAI) is very important to recognize risk factors related to CAI. This facilitates prevention of injury and management of the associated musculoskeletal deficits of CAI. Objective:  to assess endurance of trunk muscles in females with CAI. Methods: This study consisted of 62 females, allocated into two equal groups of 31; the experimental group (A) included females with CAI and the healthy control (Group B) included healthy females. McGill core endurance tests (prone-bridge, right side-bridge, left side-bridge, trunk flexion and horizontal back extension) were administered to assess trunk muscle endurance. Results: Statistical analysis revealed no significant differences in trunk muscle endurance between the two tested groups (p > 0.05). Conclusions: Although, the results indicated higher values of trunk endurance in the CAI group compared with their healthy controls, no statistically significant differences were observed between the two groups. This denotes the compensatory mechanism that altered ankle-hip strategy.
Administrative-Territorial Reformes Conducted In Central Asia And Its Results
Authors: Normatov Otabek Maxamatjonovich  , Mamadaminova Bakhtigul Abdupattayevna  , Sulaymanova Shohsanam Absamatovna
Published: November 2023

This article talks about the regionalization processes carried out in 1926 and their special role in the development of the newly formed republics and autonomous regions in this direction. Information is also provided on the administrative units of the newly formed republics in Central Asia, the preparatory processes for determining their borders and territories, and the total population of the Soviet republics and autonomous regions. In particular, it was emphasized that the administrative and economic zoning carried out in the Uzbek SSR, the first regions created in the republic, on the one hand, for the development and economy of the national economy, and on the other hand, for the division into new administrative regions and management systems, were of great importance .
Impact of Frame-By-Frame Monitoring of Embryos on Obstetric And Perinaaaaatal Outcomes In Singleton Pregnancies In Assisted Reproductive Technology Programs
Authors: Yuldasheva Suraya Zarifovna  , Yulduz Gulyamovna Rasul-zade
Published: November 2023

The embryological stage of the implementation of ART programs can be considered one of the most important, since the assessment of the competencies or "quality" of oocytes, their fertilization and in vitro cultivation to the stage of preimplantation embryos largely determine its success. . An efficient method of embryo selection is currently in high demand in this field, since it is a method of selecting embryos that have the highest potential for implantation. Almost all publications on time-lapse microscopy have focused on timing specific embryonic division events and then using this information to create algorithms to help select an embryo for transfer, but there are insufficient data on obstetric and perinatal outcomes.
The Use of Artificial Intelligence in Interactive Virtual Reality Adaptive Environments with Real-Time Biofeedback Applied to Phobias Psychotherapy
Authors: Gomes Paulo Veloso , Sá Vítor J. , Donga João , Marques António , Gomes Bárbara , Almeida Raquel Simoes de , Pereira-Loureiro Javier
Published: November 2023

Exposure therapy is a type of psychotherapy where the patient is gradually exposed to a fear situation. Patients may present different degrees of phobia, and the degree of phobia of each patient changes throughout the treatment. The use of Interactive Virtual Reality Adaptive Environments, where the interaction is personalized through real-time biofeedback mechanisms, allows the environment to adapt to the patients and their evolution throughout the treatment. The Artificial Intelligence affective algorithms continuously monitor the patient’s behavioral data and physiological responses to adjust the intensity and number of the stimuli. This real-time adaptation aims to personalize and optimize the exposure process, gradually desensitizing patients to their fears
Use of Deep Learning Techniques for Motor Events Detection in Polysomnographic Records
Authors: Lloves García Inés , Álvarez-Estévez Diego
Published: November 2023

Sleep medicine deals with the diagnosis and treatment of sleep-related disorders. The diagnosis is carried out through the manual analysis and labeling of polysomnographic studies, which record various electrophysiological and pneumological signals of the patient throughout the night. This process involves the analysis of long duration signals, is complex, and demands considerable resources and time on the part of the clinical expert. The purpose of this proyect is the construction of automatic analysis algorithms that considerably reduce the analysis duration, reducing the manual workload, and minimizing possible human errors, providing repeatability and robustness. In particular, the objective is to use machine learning algorithms, based on Deep Learning techniques, for the identification and location of physiological events in these polysomnographic records. Specifically, the goal is to locate physiological events associated with involuntary motor movements that occur in the limbs, known as Limb Movements
Influence of climate variability on fire generation
Authors: Ferrelli Federico , Casado Ana
Published: November 2023

This study evaluates the occurrence of dry and wet events and their relationship with fires in southern Pampas, Argentina. The intensity and magnitude of dry and wet events were determined based on the regional series of the Standardized Precipitation and Evapotranspiration Index (SPEI) for the 2000-2021 period. The data obtained were related to the El Niño Oceanic Index (ONI) to analyze the incidence of El Niño and La Niña events in generating them. Fires in the region were detected using remote sensing techniques, considering the number of events, their intensity, extent, and duration. The southern Pampas experiences marked rainfall variability, with 15 dry events, 11 wet years, and 2 standard years recorded for the period analyzed. Extreme dry years were, on average, more intense (SPEI = -2.14) and occurred mainly during the negative ONI phase. In contrast, extreme wet years exhibited lower intensity (SPEI = 1.98), and only the most intense ones were related to neutral ONI phases. We analyzed a representative extremely dry (ED) and an extremely wet events (EW) to interpret the relationship between climate variability and the spatiotemporal variability of fires in the region. It was observed that during the EW event (2014-2015, SPEI = 1.52, and El Niño event until 2015) the number of fires was higher compared to an ED event (2008-2009, SPEI = -2.22, and La Niña event during 2008), with 460 and 205 fires, respectively. The intensity was higher in the EW (302.6 and 31.5 MW), while the area presented considerable differences (1722 and 815.5 km2, respectively). Finally, the duration of the fires was shorter in ED than in EW (6 and 8 months, respectively). These results were related to vegetation health (NDVI = 0.29 and 0.41 and EVI = 0.15 and 0.21 in ED and EW, respectively) and changes in land covers. This study provides a solid database for future research efforts and sustainable land management plans.
Evaluation of diagnostic accuracy of latex agglutination test and E-test for the detection of methicillin-resistant Staphylococcus aureus
Authors: Gupta Nupur , Jais Manoj , Sharma Aditi , Shrivastava Priyanshu K.
Published: November 2023

Background: This study was undertaken to compare the phenotypic methods of latex agglutination test and e-test with polymerase chain reaction for the detection of methicillin-resistant Staphylococcus aureus.
Methods: Two hundred pus samples obtained from different clinical disciplines were subjected to the latex agglutination test and minimum inhibitory concentration by e-test (Oxacillin and Vancomycin) as per the standard guidelines. The comparison was made with polymerase chain reaction as the reference test. The diagnostic accuracy of each method was reported in terms of sensitivity, specificity, positive predictive value, and negative predictive value.  
Results: The sensitivity of latex agglutination test was found to be 100% whereas e-test for Oxacillin was found to be 96.67% sensitive. Higher specificity for e-test was reported (99.41%) when compared to the latex agglutination test (97.65%).
Conclusions: Latex agglutination and e-tests are tests are relatively simpler, rapid, and easy-to-perform methods when compared to polymerase chain reaction. The present study reported high sensitivity and specificity values for both the tests, and therefore supports usage of the stated methods as screening tools for methicillin-resistant S. aureus. However, more multi-centric studies are recommended to precisely determine the diagnostic accuracy of these phenotypic methods.
Port site tuberculosis and retained gall stone after laparoscopic cholecystectomy
Authors: Kumar Vivek , Siddiqui Azaz Akhtar , Kesiezie Khriethonuo , Goel Mahak , Kumar Arun , Bhattacharya Jenna B. , O. V. Fathima
Published: November 2023

Laparoscopic cholecystectomy is one of the most common general surgical procedures performed. Port site infection is common surgical site infection. However, tuberculosis of port sites is very uncommon. We report a case of a 36-year-old lady who was presented to our center with complaint of swelling at midclavicular port and seropurulent discharge from epigastrium port site for one month after laparoscopic cholecystectomy done outside. Patient underwent wide local excision with stone retrieval and histopathology of specimen was suggestive of chronic inflammation. Following excision patient again develop swelling at scar site and FNAC from swelling reveal feature of tuberculosis, subsequently patient was started on anti-tubercular drug therapy and follow-up after 2 months show healthy suture line with no sinus or discharge or swelling.  Port site tuberculosis in absence of tuberculosis of gall bladder and abdominal is most likely due to contamination of instrument or dressing by mycobacterium tuberculosis. Diagnosis is made by ZN staining or FNAC or biopsy. Management includes incision and drainage or debridement or wide local excision with anti-tuberculosis medication. Following standardized sterilization procedure is essential for prevention.
Using Corpora for English Language Teacher Education (ELTE)
Authors: Walsh Steve
Published: November 2023

The article seeks to explore the use of corpora in the training and professional development of English language teachers. It will be argued that in ELTE (English Language Teacher Education), the use of corpus-based approaches offers a wide range of possibilities which enable and promote reflection, encourage the sharing of best practice and foster data-driven practice procedures. The analytical core of the paper focuses on two examples of integrating corpora into ELTE—CLCA, an amalgamation of corpus linguistics and conversational analysis, and SETTVEO, a combination of the SETT (Self-Evaluation of Teacher Talk) framework and the VEO (Video Enhanced Observation) app. The former provides insights into enhanced understandings of spoken interaction and its relationship with learning. The latter aids teachers in developing their classroom interactional competence by collecting reflective and interactional data so as to establish and evaluate a dialogic and collaborative approach to reflective practice.
The Role of Information and Communication Technologies (ICT) in Early Childhood Education. Integrating Educational Software into Activity
Authors: Iancu Aurelia
Published: November 2023

The importance of using ICT in education has been highlighted and emphasized in the international literature. The main impact of this is at the level of curriculum design and development. The study is based on the integration of information and communication technologies into current training methods, the essence of which is to rethink the way learning takes place and the roles of the two main educational actors: the teacher and the learner. In this new context, this study aims to provide a theoretical and structural perspective on ICT, as well as the role and weight of different components of the curriculum system in the design of learning programmes based on the integration of ICT in training and assessment activities. It is well known that for pre-school children, the element of novelty that emerges in all activities carried out in the instructional-educational process plays a very important role. The more this element is present, the better their attention and memory are stimulated, enabling them to concentrate better on the tasks at hand. It is now a fact that all children are attracted to computer games and all activities involving their use. In order to maximize the time spent in front of the computer for the benefit of children, and because we have educational software suitable for preschoolers, we have formulated the objectives and hypotheses of this work, based on the premise that the attention of children who use this educational package will have a progress of memory in both quantitative and qualitative analysis.
Hook-effect in the endocrinology practice: case-report
Authors: Tsiberkin A. I. , Timkina N. V. , Zayachkovskiy N. A. , Paltsev A. A. , Grineva E. N.
Published: November 2023

In this study, we described a case that illustrates the clinical significance of the hook-effect, a laboratory phenomenon when the measured hormone level is falsely lowered due to the binding of signaling antibodies with high analyte concentration. In a patient with a newly diagnosed 2.7 x 1.7 x 2.1 cm pituitary macroadenoma, laboratory testing revealed an increase in prolactin level to 878.6 mMU/ml (105.0–540.0 mMU/ ml). The abnormality was interpreted as a secondary increase hyperprolactinemia due to pituitary stalk compression, and the patient was referred for surgery. Upon admission to the hospital, the prolactin level was measured repeatedly using a more modern test system and the level was 2 296.0 ng/ml (4.0–15.2) without detecting a significant amount of macroprolactin. The degree of hyperprolactinemia indicated the presence of macroprolactinoma. The patient was discharged from the neurosurgical department with a recommendation to start dopamine agonists treatment, which showed an excellent biochemical response. A personalized approach to the differential diagnosis of hyperprolactinemia, which takes into account not only a wide range of pathological conditions, but also a number of laboratory phenomena, reduces the risks of unjustified surgical interventions in patients with prolactinomas.
Immersive virtual reality as a social research environment. The impact of the presence of an embodied agent on the Stroop task performance based on own research
Authors: Walas Aleksander
Published: November 2023

This empirical study examined the effects of the presence of others (physical observers and embodied agents) on the performance of the Stroop task within an immersive virtual reality (VR) environment. Drawing from the research conducted by Pascal Huguet and his colleagues, who explored the social facilitation and inhibition effects in traditional lab conditions using the Stroop test, the current study sought to test these effects in VR conditions. Participants were divided into four groups, each experiencing different conditions – performing the task alone, under the awareness of being observed, or in the presence of embodied agents (formally dressed as Dr. Piotr or casually as Piotrek). A one-way analysis of variance (ANOVA) for independent samples was conducted to evaluate the results. Findings showed a significant reduction in Stroop interference when participants were aware of being observed by the experimenter. However, the presence of embodied agents in the VR environment, regardless of their regardless of their dress or manner of presentation, did not significantly influence the results. These results not only confirmed the occurrence of the Stroop interference effect in VR conditions, comparable to traditional lab conditions, but they also suggested that the social presence of the experimenter could enhance task performance in the VR environment. There was no significant influence observed from the presence of embodied agents, though. These observations can greatly contribute to the development of VR. However, further research is required to expand these findings, considering factors such as sample size and realism of embodied agents.
Katolicki tygodnik „Idziemy” wobec pełnoskalowej inwazji Rosji na Ukrainę
Authors: Leśniczak Rafał
Published: November 2023

Celem podjętej analizy jest próba określenia stanowiska redakcji ogólnopolskiego tygodnika katolickiego „Idziemy” dotyczącego działań politycznych rządu Mateusza Morawieckiego, jak również polskich biskupów i papieża Franciszka w kontekście pełnoskalowej inwazji Rosji na Ukrainę. Materiał badawczy stanowiły drukowane wersje periodyku od 20.02.2022 do 24.04.2022. Wykorzystano metodę analizy zawartości, uzupełnioną o element hermeneutyczny. Tygodnik wyrażał poparcie dla działań politycznych rządu premiera Morawieckiego w obszarze bezpieczeństwa militarnego i bezpieczeństwa energetycznego. Ponadto aprobatywnie zaprezentowano działania podjęte przez polityków Zjednoczonej Prawicy w kontekście kryzysu uchodźczego. Periodyk poparł stanowisko polskich biskupów i papieża Franciszka dotyczące wojny rosyjsko-ukraińskiej.
Między uwidacznianiem a zacienianiem. Zarządzanie jawnością w doświadczeniu matek tworzących rodziny nieheteronormatywne w Polsce
Authors: Wojciechowska Magdalena
Published: November 2023

Celem artykułu jest przyjrzenie się temu, w jaki sposób polskie pary jednopłciowe, które wspólnie wychowują dziecko poczęte w ramach związku, funkcjonują na co dzień w różnych wymiarach przestrzeni społecznej. Działając w niesprzyjających warunkach społeczno-kulturowych, czego egzemplifikację stanowi marginalizacja osób wykraczających poza heteronormę, kobiety projektują różne strategie interakcyjne, które pozwalają im zarządzać jawnością rodziny i tym samym chronić ją przed antycypowaną przemocą symboliczną. Ich działania w tym zakresie dotyczą aktywności w ramach przestrzeni miejsc prywatnych, wspólnych oraz zinstytucjonalizowanych i są zorientowane na uwidacznianie bądź zacienianie konstelacji rodziny, także za sprawą „uchodzenia” (passing). Analiza nakierowana jest na ukazanie, że określone sposoby praktykowania rodziny, choć przyczyniają się do osiągania zamierzonych celów, w dłuższej perspektywie mogą prowadzić do podtrzymywania norm, które uczestniczki badania uważają za marginalizujące. Przytaczane wnioski są oparte na sześcioletnich badaniach dotyczących doświadczania macierzyństwa nieheteronormatywnego, które zrealizowano z udziałem 21 polskich par kobiet wychowujących dziecko poczęte w czasie trwania ich związku.
Znaczenie mediów społecznościowych w postrzeganiu wizerunku miasta na przykładzie Łodzi
Authors: Łaska-Formejster Alicja , Kowalska Dominika
Published: November 2023

Media społecznościowe wykorzystywane przez podmioty i instytucje zajmujące się marketingiem terytorialnym stały się dla nich ważnym narzędziem w przekazywaniu informacji, kreowaniu marki oraz wizerunku i promowaniu podejmowanych przez nie działań. W analizie, której wyniki zostały przywołane w niniejszym artykule, istotne było określenie wpływu mediów społecznościowych poświęconych Łodzi i ich oddziaływania na kształtowanie wizerunku miasta w opinii badanych osób. Badanie zrealizowane zostało metodą ankiety internetowej (CAWI), zamieszczonej na trzech portalach społecznościowych związanych z Łodzią (Aktywna Łódź, Łódź – Mieszkańcy Łodzi, Łódź ♥). Z analizy wynika, że social media, profile Łodzi, skutecznie przyczyniają się do budowania i wzmacniania marki miasta, są źródłem informacji, wymiany opinii, sugestii i rekomendacji oraz inspiracją i podstawą podejmowanych przez użytkowników decyzji. Czynnikami kształtującymi wizerunek miasta są jego atmosfera, infrastruktura oraz zasoby kulturalne i sportowe, szczególnie zaś (cykliczne i jednorazowe) wydarzenia właśnie o charakterze kulturalnym i sportowym.
Preceptors and the New Neonatal Nurse Practitioner Educational World
Authors: Moss Colleen Reilly , Savin Michele , Sharpe Elizabeth , Wallman Carol
Published: November 2023

The need for neonatal nurse practitioner (NNP) preceptors has never been greater. Precepting is a professional responsibility with both rewards and challenges. The recent pandemic has brought about new challenges, not the least of which is burnout from clinical, learner, and environmental demands. A new educational model from the American Association of Colleges of Nursing and the National Task Force outlines educational and preceptor requirements aimed at improving the advanced practice educational experience for students and preceptors. Available research provides evidence of what preceptors value and how to develop best practices with academic institutions to advocate for their students. This article will discuss new nursing educational models and the role of the NNP preceptor and analyze current best practices in preceptor recruitment and retention while discussing national trends impacting personal and professional NNP practices.
Detection of mRNA and Anibody in Mice Injected withPlasmid pCDNA3.1-SRM Carrying African SwineFever Virus Gen Able to Produce Self-Replicating RNA
Authors: Mahardika Gusti Ngurah Bayu Krisna , Pharmawati Made , Ramona Yan
Published: November 2023

Vaccine technology and gene therapy have been well developed, in which DNA and mRNA is used as a base. This technology has a drawback as high quantities of DNA/RNA are needed, and therefore it is not feasible economically, especially for animals. Self-replicating/amplifying RNA (saRNA) is a promising technology to cope with the drawback of DNA and mRNA vaccines. A pCDNA3.1-SRM plasmid with a gene of picornavirus encoding polymerase enzyme and 5’-and 3’-untranslated region (UTR) might produce saRNA to be used as a vaccine. In this research, the pCDNA3.1-SRM plasmid was inserted with DNA “ASF-276R-224L” encoding antigens for the African swine fever (ASF) virus. The main aim of this research was to compare the amount of mRNA and antibody of the pCDNA3.1-SRM vaccine with the pCDNA3.1 without polymerase gene as a control vaccine in mice. A total of 46 mice were divided into four groups according to the amount of plasmid per vaccine and type of plasmid. The mRNA quantity was obtained from CT-Values in the qRT-PCR analysis of mice thigh muscles that were sampled at day 3, 6, and 9 post-injections. African swine fever antibodies were measured using ELISA applying synthetic peptides and the optical density (OD) were statistically analysed using T-test method. The results of both mRNA quantity and antibody level of pCDNA3.1-SRM were found to be higher when compared to the control vaccine, but they are not significantly different statistically (p>0.05). For future research, it is recommended to improve the construction of pCDNA3.1-SRM plasmid.
KARAKTERISTIK UKURAN TUBUH KAMBING SENDURO ASAL SENDURO LUMAJANG JAWA TIMUR
Authors: Prasetyo Guruh , Susilorini Tri Eko , Septian Wike Andre , Tribudi Yuli Arif , Efendi Ahmad Zarkasi , Hidayah Nur , Damayanti Heri , Suyadi Suyadi
Published: November 2023

Keragaman plasma nutfah merupakan sumber bahan genetik yang mempunyai nilai guna yang eksistensinya perlu dilindungi dan dilestarikan. Plasma nutfah kambing asli Indonesia salah satunya adalah kambing senduro, yang sudah ditetapkan oleh Keputusan Kementerian Pertanian No.1055/Kpts/SR.120/10/2014 yang berasal dari Kecamatan Senduro, Kabupaten Lumajang, Jawa Timur. Tujuan penelitian adalah menganalisis sifat fenotipe kambing senduro berdasarkan sifat kuantitatifnya. Pengamantan fenotipe meliputi panjang badan, lingkar dada, tinggi pundak, panjang telinga, panjang rambut rewos dan korelasi setiap sifat fenotip tersebut. Materi yang digunakan pada penelitian ini adalah kambing Senduro jantan dan betina dewasa masing-masing sebanyak 14 dan 25 ekor. Kambing senduro yang diamati pada kambing dengan kondisi gigi seri ke-3 (I3) telah diganti oleh gigi permanen yaitu kambing senduro berumur 2-4 tahun. Data morfometrik yang diperoleh dihitung rata-rata, simpangan baku serta korelasi antar ukuran morfometrik menggunakan program Genstat 14.2 kemudian dianalisis secara deskriptif. Hasil penelitian ini menunjukkan bahwa kambing senduro memiliki bobot badan 24,56 ± 5,48 kg (jantan) dan 26,84 ± 6,50 kg (betina), panjang badan 63,89 ± 4,76 cm (jantan) dan 63,32 ± 6,29 cm (betina), lingkar dada 61,67 ± 4,36 cm (jantan) dan 66,48 ± 6,56 cm (betina), tinggi pundak 66,33±4,53 cm (jantan) dan 64,71 ± 5,76 cm (betina), panjang telinga 31,22 ± 2,17 cm (jantan) dan 28,13 ± 2,74 cm (betina), panjang rambut rewos/surai 17,56 ± 1,67 cm (jantan) dan 14,58 ± 2,39 cm (betina). Ukuran morfometrik pada kambing senduro berkorelasi positif satu sama lain. Terdapat korelasi yang sangat signifikan antara lingkar dada, panjang badan dan tinggi badan dengan bobot badan pada kambing senduro.
PROMENE U PRISTUPU ISTRAŽIVANJA MANJINSKIH KULTURA
Authors: THOMKA Beáta
Published: November 2023

A 21. század első negyedének kutatásai olyan szempontokat vetnek fel, amelyek alkalmasak a kisebb közösségek irodalmi tevékenységének történeti értelmezésére, valamint jelenkori változásaik követésére is: „a regionális irodalomtörténetek révén újra polgárjogot nyernek a marginalizált vagy elnyomott csoportok irodalmai, maguk a régiók pedig kikerülnek a marginalizált pozícióból” (John Neubauer). A dolgozat a minor kulturális fogékonyság és a regionális pluralizmus kérdéseiben a szűkebb-tágabb régiónkból, vagy kisebb európai kultúrák köréből származó teoretikusok javaslatait érinti. Nem véletlen, hogy olyan irodalmárok igyekeznek rávilágítani a kisebbségi pozíciók, a többnyelvű közegek és a hierarchikus szerkezetű, nemzetközpontú koncepciók összeférhetetlenségére, akiket a tárgykör kutatása iránt saját tapasztalataik is érzékennyé tettek (Ďurišin, Fried, Neubauer, Tihanov, Thomsen, Brajović, Juvan, Grčević, Kovač).
HATVANY LAJOS ELSŐ EMIGRÁCIÓJA ÉS DAS VERWUNDETE LAND CÍMŰ MUNKÁJA
Authors: BIRÓ Annamária
Published: November 2023

Hatvany Lajos tagja volt annak a küldöttségnek, amelyik Károlyi Mihály vezetésével a Magyar Nemzeti Tanács képviseletében 1918. november 7-én Belgrádba utazott a fegyverletételi szerződés konkretizálására. Itt szerzett kiábrándító tapasztalatait először lapjában, a Pesti Napló hasábjain publikálta 1918-ban, majd pedig bécsi emigrációjában a kudarc okait végiggondolva 1921-ben adta ki a Romain Rolland-nak ajánlott Das verwundete Land című kötetét, melyben a külföldi olvasóknak próbálja elmagyarázni a magyarság szenvedéstörténetét. A dolgozat Hatvany Lajos emigrációjával és az említett kötettel és annak recepciótörténetével foglalkozik, választ keresve arra a kérdésre, hogy a többszörösen kirekesztett Hatvany miért vágyik vissza mégis folyamatosan Magyarországra.
MÁRAI SÁNDOR ÉS AZ AMERIKAI MELEG EMANCIPÁCIÓ
Authors: CSEHY Zoltán
Published: November 2023

Ez a tanulmány Márai Sándor naplói alapján vizsgálja meg az író viszonyát az amerikai meleg mozgalmak emancipációs törekvéseihez, illetve tárja fel az emigráns író Amerika-képének freudista alapozású pszichoszexuális vonatkozásait. Egy meglehetősen széles nyomtávú diskurzusról van szó, mely Walt Whitman költészetének megítélésétől kezdődően meleg bűntényeken, művészeti alkotásokon és politikai manipulációkon (pl. a Chambers–Hiss-eset), vagy a San Diegó-i pride leírásán át a homoszexualitáshoz társított intellektuális elitizmus démonizálásáig vezet.
GION NÁNDOR LATROKNAK IS JÁTSZOTT CÍMŰ TETRALÓGIÁJÁNAK GENETIKUS SZÖVEGVIZSGÁLATA
Authors: HORVÁTH FUTÓ Hargita
Published: November 2023

A tanulmány a szöveggenetika vizsgálati módszereivel gyűjti össze Gion Nándor Latroknak is játszott című regénytetralógiája keletkezésének dokumentumait, és rekonstruálja az alkotói folyamatot a hagyatékban fennmaradt átdolgozott, javított kéz- és gépiratok (szűkebb értelemben vett genetikus dosszié) alapján, amelyek az írás folyamatát tükrözik. A regények létrejöttének vizsgálatát a tágabban értelmezett genetikus dosszié részét képező egyéb segédanyagok (levelek, fényképek, képeslapok, kereszt- és házasságlevelek, korabeli újsá- gok, történelmi források, vázlatok stb.) is segítik, a tanulmány ezeket is számba veszi. Az anyag nagyobb része az Országos Széchényi Könyvtár Kézirattárában található a Fond 583/1‒22. jelzet alatt, néhány dokumentum pedig a szenttamási Gion Nándor Emlékház Kézirattárában. A mű szövegforrásait feltáró munka dokumentálja a korpusz szövegváltozatait is az elő-szövegektől az utó-szövegekig, azaz a különböző nyomtatott variánsokig.
Efeitos de um grupo educativo nas práticas parentais promotoras do desenvolvimento infantil
Authors: Costa Priscila , CINTRA THATIANNE FERREIRA GOMES , Cordeiro Samara Macedo , De Andrade Paula Rosenberg , Veríssimo Maria de la Ó Ramallo
Published: November 2023

Objetivo: avaliar os efeitos de um grupo educativo nas práticas parentais promotoras do desenvolvimento infantil adotadas por familiares de lactentes. Métodos: ensaio clínico randomizado de abordagem quantitativa conduzido em serviço de atenção básica com familiares de lactentes. O grupo controle recebeu acompanhamento de saúde usual, e o grupo experimental foi convidado para interagir com o grupo educativo. As práticas parentais foram avaliadas utilizando o instrumento da Organização Mundial da Saúde (OMS) e do Fundo das Nações Unidas para a Infância (Unicef) para avaliação do cuidado promotor do desenvolvimento infantil. Resultados: participaram do estudo 21 familiares de lactentes. Após a intervenção, houve um aumento de práticas parentais no grupo experimental, como brincar com objetos domésticos (46,1% versus 12,5% no grupo controle), brincar com brinquedos feitos em casa (38,5% versus 12,5% no grupo controle) e contar histórias com livros infantis (38,4% versus 12,5% no grupo controle). Conclusão: os grupos educativos apoiaram práticas parentais de promoção do desenvolvimento de lactentes.
Indikátorok használata az innovációs teljesítmény mérésére a magyar egyetemeken – egy empirikus felmérés tapasztalatai
Authors: Buzási Zoltán , Jelen Tibor
Published: November 2023

A felsőoktatási intézmények innovációs tevékenységét, tudástranszfer-funkciójának érvényesülését indikátorokkal mérik. Az indikátorokkal való mérésnek – célszerűsége ellenére – számos elvi és gyakorlati korlátja van. Ez a tanulmány összefoglalja annak az empirikus felmérésnek az eredményeit, amelyben a szerzők olyan, kiválasztott indikátorokat vizsgáltak, amelyek alkalmasak lehetnek a felsőoktatási intézmények innovációs, szellemitulajdon-védelmi és technológiatranszfer-tevékenységének, illetve az e tevékenységeken belüli szervezeti teljesítmények mérésére, egyrészt az intézményen belül, másrészt az intézmények közötti összehasonlításban. Az empirikus felmérés eredményeinek elemzése segít áttekinteni a komplex és sokrétegű szempontrendszer azon, néhány hangsúlyosnak tekintett elemét, amelyek alapján kiválaszthatóvá válnak a megfelelő tartalmú indikátorok – akár a saját használatú, intézményen belüli mutatók, akár egy ágazati szintű, standard indikátorkészlet. A tanulmány szerzői a bemutatott helyzetkép alapján javaslatokat fogalmaznak meg az indikátorok használatára vonatkozóan, a jelenlegi gyakorlat jobbá tétele érdekében.
Systematic review on training models for partial nephrectomy
Authors: Farinha Rui J. , Mazzone Elio , Paciotti Marco , Breda Alberto , Porter James , Maes Kris , Van Cleynenbreugel Ben , Vander Sloten Jozef , Mottrie Alexandre , Gallagher Anthony G.
Published: November 2023

Robot-assisted partial nephrectomy (PN) is a complex and index procedure with a difficult learning curve that urologists need to learn how to perform safely. We systematically evaluated the development and validation evidence underpinning PN training models (TMs) by extracting and reviewing data from PubMed, Cochrane Library Central, EMBASE, MEDLINE, and Scopus databases from inception to April 2023. The level of evidence was assessed using the Oxford Center for Evidence-Based Medicine. Of the 331 screened articles, 14 cohort studies were included in the analysis. No randomized controlled trials were found, and the heterogeneous nature of the models, study groups, task definitions, and subjectivity of the metrics used were transversal to all studies. All the models were rated good for realism and usefulness as training tools. Methodological discrepancies preclude definitive conclusions regarding the construct validation. No discriminative or predictive validation evidence was reported, nor were there comparisons between an experimental group trained with a TM and a control group. The previous findings stand for the low level of evidence supporting the efficacy of the described TMs in the acquisition of skills required to safely perform PN.
Uncovering the Blueprint of Aging: How Aging Causes Late-Life Disease
Authors: Kern Carina , Stebbing Justin
Published: November 2023

The evolutionary theory of aging, particularly antagonistic pleiotropy (AP), provides an account of the ultimate origins of aging. What remains unclear is the nature of the proximate mechanisms by which AP gives rise to diseases of aging, like cardiovascular disease and Alzheimer’s disease. Damage-centric theories focusing on loss of genetic and cellular function have been proposed, as well as programmatic theories focusing on unwanted gene and cellular function. The latter include the hyperfunction and developmental theory that view aging as the futile continuation, or run-on, of growth and developmental programmes into later life. Yet neither type of theory has performed well in explaining late-life disease aetiology, particularly with respect to disease onset, presentation and progression. What is proposed here in this review is a new programmatic theory of aging. We argue that the emergence of many specific diseases may involve quasi-programmes that are not the result of run-on, but rather are triggered by other factors in late life. Such triggers may be non-programmatic (e.g. infection, mechanical injury) or programmatic. Moreover, the consequent pre-pathological and pathological changes may in some cases trigger further changes, leading to futile and destructive cascades of quasi-programmes and pathology. The origins of triggered quasi-programmes can be traced to biological constraint i.e. the inability of organisms to optimise all functions at once. And, to some extent, the new theory presented here revises the understanding of AP. That is, because any gene can be triggered in an erroneous manner, every gene is potentially an AP gene that risks pathology, though level of risk varies according to constraint. To help validate the theory, we test it against several complex diseases of aging. The new model in this review attempts to provide a blueprint understanding that, to a certain extent, closes the gap in the causal chain of events between evolutionary causes of aging and the aetiology of age-related diseases. It also helps to explain why certain disorders mimic accelerated aging and how interventions, such as the suppression of IIS and mTOR retard many aspects of aging; notably, though, unlike prior programmatic theories, the new theory is not mTOR-centric. Finally, it provides new perspectives on possible treatment of aging.
The Viable but Non-Culturable (VBNC) State, a Poorly-Explored Aspect of Beneficial Bacteria
Authors: Pazos-Rojas Laura Abisaí , Cuellar-Sánchez Alma , Romero-Cerón Ana Laura , Rivera-Urbalejo América , Van Dillewijn Pieter , Luna-Vital Diego Armando , Muñoz-Rojas Jesús , Morales-García Yolanda Elizabeth , Bustillos-Cristales María del Rocío
Published: November 2023

Many bacteria have the ability to survive in challenging environments; however, they cannot grow on standard culture media, a phenomenon known as the Viable but Non-Culturable (VBNC) state. Bacteria commonly go into the VBNC state under nutrient-poor environments or under stressful conditions. This review explores the concept of the VBNC state, providing insights into the beneficial bacteria known to employ this strategy. The investigation covers different chemical and physical factors that can induce the latency state, cell features, and gene expression observed in cells in the VBNC state. The revision also covered the significance and applications of beneficial bacteria, methods for evaluating bacterial viability, the ability of bacteria to persist in environments associated with higher organisms, and the factors that facilitate the return to the culturable state. Knowledge about beneficial bacteria capable of entering the VBNC state remains limited, however, beneficial bacteria in this state could face adverse environmental conditions, and return to culturable state when conditions become suitable and continue to exert their beneficial effects. Likewise, this unique feature positions them as potential candidates for healthcare applications, such as the use of probiotic bacteria to enhance human health, applications in industrial microbiology for the production of prebiotics, functional foods, and in the beer and wine industry. Moreover, their use in formulations to increase crop yield and for bacterial bioremediation offers an alternative pathway to harness their beneficial attributes.
First Sero-Epidemiological Investigation of SARS-CoV-2 among Students and Staff of Polytechnic High School a Community of Cheikh Anta Diop University after the Fourth Wave of COVID-19 in Senegal
Authors: THIAM Fatou , Diouara Abou Abdallah Malick , NDIAYE Clemence Stephanie Chloe Anoumba , DIOUF Ibrahima , KEBE Khadim , SENGHOR Assane , DJOUMOI Djibaba , MBAYE Mame Ndew , DIOP Idy , SANE Sarbanding , COUNDOUL Seynabou , Tene Sophie Deli , DIOP Mamadou , Dieng Abdou Lahat , NDIAYE Mamadou , DIOUF Massamba , Sall Saïdou Moustapha , NGUER Cheikh Momar
Published: November 2023

Cross-sectional survey was conducted to capture the true extent of COVID-19 exposure among students and staff of Polytechnic High School (PHS). Random cluster sampling was carried out between May 19 and August 18, 2022, after the fourth wave of COVID-19 transmission. IgM and IgG SARS-CoV-2 antibodies were screened using WANTAI SARS-CoV-2 ELISA assays. Seroprevalence and descriptive statistics were calculated. Moreo-ver, the association between seropositivity and different factors (age, gender, preventive measures comorbidity, and symptoms, etc.) was determined using Logistic Regression. The overall IgG and IgM seroprevalence were 92% and 6.91% respectively. We found a higher IgM seroprevalence in men than women (9.4% vs. 5.6%) and a lower IgM seroprevalence in (18-25) age group compared to (55-65) years. Low compliance with preventive measures was found with a significant IgM seroprevalence depending on non-respect of social distancing (p = 0.008). A total of 70% of participants presented symptoms linked to COVID-19 at the moment of the survey. Results revealed a significant difference according to IgG seroprevalence among participants who declared fa-tigue symptoms 92.06% compared to those who did not 80.39% (p = 0.0027). IgM seropositivity was associated with Body Mass Indice (BMI) categorized (O.R. 0.238, p = 0.043), ethnic group (O.R. 0.723, p = 0.046) and marital status (O.R. 2.399, p = 0.021). Moreover, IgG seropositivity was associated with Chronic sinusitis comorbidity (O.R. 0.238, p = 0.043) and vaccination status (O.R. 4.741, p < 0.001). The majority of students and staff have al-ready been exposed to SARS-CoV-2 and confirm the circulation of SARS-CoV-2 in PHS at the time of the survey. Our results underline the importance of sero-epidemiological surveys to estimate the real impact of the COVID-19 pandemic in a community and to monitor disparities in antibody response in the population.
RTMN 2.0 – an Extension of Robot Task Modelling and Notation (RTMN) Focus on Human Robot Collaboration
Authors: Zhang Sprenger Congyu , Corrales Ramón Juan Antonio , Baier Norman Urs
Published: November 2023

This paper describes RTMN 2.0 - an extension of the modeling language RTMN. RTMN combines process modeling and robot execution. The reusability and intuitive robot programming allows people without programming expertise to plan and control robots. While RTMN focuses on the ease of use and flexibility of robot programming by providing an intuitive modelling language, RTMN 2.0 concentrates on Human Robot Collaboration (HRC), which represents the current trend of the industry shift from ‘mass-production’ to ‘mass-customization’. While traditional robot systems provide high payload capabilities and repeatability, they suffer from limited flexibility and dexterity. Therefore, human-robot collaboration is a suitable arrangement to leverage the unique capabilities of both humans and robots for increased efficiency and quality in industrial scenarios. HRC has made a great impact on the robotic industry: increased efficiency, reduced costs and improved productivity, which can be adopted to make up for the skill gap of a shortage of workers in the manufacturing industry. The extension in RTMN 2.0 includes the following notations: HRC tasks, requirement, Key Performance Indicator (KPI), condition check and decision making, join/split and data association. With all these additional elements RTMN 2.0 covers the full scale of agile manufacturing – light out and collaborative.
Role of Telomere Length in Survival of Patients with Idiopathic Pulmonary Fibrosis and Other Interstitial Lung Diseases
Authors: Tesolato Sofía , Vicente-Valor Juan , Jarabo Jose-Ramón , Calatayud Joaquín , Saiz-Pardo Melchor , Nieto Asunción , Álvaro-Álvarez Dolores , Linares María-Jesús , Fraile Carlos-Alfredo , Hernando Florentino , Iniesta Pilar , Gómez-Martínez Ana-María
Published: November 2023

Interstitial lung diseases (ILDs) constitute a group of more than 200 disorders, being idiopathic pulmonary fibrosis (IPF) one of the most frequent. Telomere length (TL) shortening causes loss of function of the lung parenchyma. However, little is known about its role as prognostic factor in ILD patients. With the aim of investigating the role of TL and telomerase activity in the prognosis of patients affected by ILDs, we analysed lung tissue samples from 61 patients. We measured relative TL and telomerase activity by conventional procedures. Both clinical and molecular parameters were associated with overall survival by the Kaplan-Meier method. Patients with IPF had poorer prognosis than patients with other ILDs (p = 0.034). When patients were classified according to TL, those with shortened telomeres reported lower overall survival (p = 0.085); differences reached statistical significance after excluding ILD patients who developed cancer (p = 0.021). In a Cox regression analysis, TL behaved as a risk-modifying variable for death associated with rheumatological disorders (RD) co-occurrence (p = 0.029). Also, in patients without cancer, ferritin was significantly increased in cases with RD and IPF co-occurrence (p = 0.032). In relation to telomerase activity, no significant differences were detected. In conclusion, TL in lung tissue emerges as a prognostic factor in ILD patients, Specifically, in cases with RD and IPF co-occurrence, TL can be considered as a risk-modifying variable for death.
Evolution of Physical Performance throughout an Entire Season in Female Soccer Players
Authors: Reyes-Laredo Francisco , Pareja-Blanco Fernando , López-Lluch Guillermo , Rodriguez-Bies Elisabet
Published: November 2023

The aim of this study was to examine the seasonal variations in relevant indices of physical performance in female soccer players. Twenty-seven female soccer players were assessed at week 2 of the season (pre-season, PS), week 7 (end of pre-season, EP), week 24 (half-season, HS), and week 38 (end of season, ES). Testing sessions consisted of: 1) vertical countermovement jump (CMJ); 2) 20-m running sprint (T20); 3) 25-m side-step cutting maneuver test (V-CUT); and 4) progressive loading test in the full-squat exercise (V1-LOAD). Participants followed their normal soccer training, which consisted of three weekly training sessions and an official match, without any type of intervention. No significant time effects were observed for CMJ height (P = 0.29) and T20 (P = 0.11) along the season. Significant time effects were found for V-CUT (P = 0.004) and V1-LOAD (P = 0.001). V-CUT performance significantly improved from HS to ES (P = 0.001). Significant increases were observed for V1-LOAD throughout the season: PS-HS (P = 0.009), PS-ES (P < 0.001); EP-ES (P < 0.001); HS-ES (P = 0.009). In conclusion, female adapted soccer training may be effective for increasing muscle strength and change of direction ability. The high volume of endurance-type training typically accumulated throughout the season may prevent any sprint and jump improvements.
Treatment of Equine Tarsus Long Medial Collateral Ligament Desmitis with Allogenic Synovial Membrane Mesenchymal Stem/Stromal Cells Enhanced by Umbilical Cord Mesenchymal Stem/Stromal Cell-Derived Conditioned Medium: Proof of Concept
Authors: Leal Reis Inês , Lopes Bruna , Sousa Patrícia , Sousa Ana Catarina , Branquinho Mariana , Caseiro Ana Rita , Rêma Alexandra , Briote Inês , Mendonça Carla , Santos Jorge Miguel , Atayde Luís , Alvites Rui , Maurício Ana Colette
Published: November 2023

Horses are high performance athletes prone to sportive injuries such as tendonitis and desmitis. The formation of fibrous tissue in tendon repair becomes a therapeutic challenge to overcome. This impels regenerative medicine to develop innovative therapies that enhance tissue regenera-tion retrieving original tissue properties. Multipotent Mesenchymal Stem/ Stromal Cells (MSCs) have been successfully used to develop therapeutic products, as they secrete a variety of bioac-tive molecules that play a pivotal role in tissue regeneration. These factors are released in cul-ture media producing conditioned media (CM). The aforementioned assumptions led to the formulation of equine synovial membrane MSCs (eSM-MSCs) – the cellular pool that naturally regenerates joint tissue, combined with medium enriched in immunomodulatory factors (among other bioactive factors) produced by umbilical cord stroma-derived MSCs (eUC-MSCs), that nat-urally contribute to suppress the immune rejection in the maternal-fetal barrier. A clinical case of an equine acute desmitis, treated with this formulation is presented. Ultrasonographic ligament regeneration occurred in a reduced time frame, reducing stoppage time and allowing return to unrestricted competition after completion of a physical rehabilitation program. This study fo-cused on the determination of the formulation therapeutic potential and the evaluation of its synergistic effect in an equine desmitis treatment, utilizing the cells themselves and its secretome.
Shear Waves in an Elastic Plate with a Hole Resting on a Rough Base
Authors: Filippov Anatoly Nikolaevich
Published: November 2023

The article is devoted to the analytical and numerical study of the pattern of propagation and attenuation, due to Coulomb friction, of shear waves in an infinite thin elastic plate with a circular orifice of radius lying on a rough base. In the field of motion, an exact analytical solution of a nonlinear boundary value problem for tangential stresses and transversal velocities is obtained in quadratures by the method of Laplace transformations. It turned out that the complete exhaustion of the wave front of a strong rupture occurs at a finite distance from the center of the hole and an elementary formula is given for this distance (the case of tangential forces instantly applied to the orifice boundary, and then constant in time, is considered). For various ratios of the magnitude of the limiting friction force to the amplitude of the applied load, the trailing wave fronts are obtained, after which a state of static equilibrium between the elastic and friction forces with a nonlinear distribution of residual deformations is established in the region .