bluuebunny/crossref_metadata_2025 huggingface dataset:
PROPOSTA DE ESCALA DE NÍVEL DE MATURIDADE PARA TECNOLOGIAS SOCIAIS
Authors: Carniello Monica Franchi , Dos Santos Moacir José
Published: December 2024

As tecnologias sociais potencialmente são uma forma de fomentar o desenvolvimento de um território, pois focam em processos que objetivam a emancipação e, em última instância, melhoria das condições de vida dos autores envolvidos. No contexto contemporâneo, há uma supervalorização das tecnologias que podem ser apropriadas pelo mercado. Para identificar os níveis de maturidade de uma tecnologia é usual utilizar a escala Technology Readiness Levels (TRL). As tecnologias sociais, por sua finalidade e natureza, não se encaixam plenamente nessa escala. O objetivo geral deste artigo é propor uma escala de maturidade para tecnologias sociais que as considerem quanto a transformação social. A pesquisa se caracteriza como exploratória e bibliográfica, de abordagem qualitativa. Os resultados apresentam uma escala de maturidade quanto a inserção e adoção das tecnologias por grupos sociais e seu potencial de transformação, considerando as fases de pré-desenvolvimento, desenvolvimento e pós-desenvolvimento.
The effect of Spirulina Platenisis supplementation on the immune response to FMD in sheep vaccinated with inactivated FMD vaccine
Authors: Mohamed Azza , Atwa Mohamed , ezaldin Diana
Published: December 2024

Spirulina's nutritional profile, non-toxicity, and medicinal properties make it a popular choice for use as a nutraceutical feed additive. This study investigates the impact of Spirulina platensis (SPL) algae addition in sheep ration on some of their haemato-biochemical parameters and the humeral immune response to the inactivated FMD vaccine. This experimental work was conducted using 15 sheep classified in 3 groups (5 sheep/ group). The first group was kept without ration additive or vaccination. The second group was vaccinated with FMD vaccine without ration additive while the third group received Spirulina platensis (SP) at the rate of 1gm / 10 kg BW /day starting from one week before vaccination and till the end of experiment (40 weeks). Evaluation of sheep immune response was investigated by measuring the total serum protein, albumin, globulin and the antibody titer by serum neutralization test (SNT) and indirect enzyme linked immune sorbent assay (ELISA). It was found that there was a marked increase in the levels of total protein, globulin and FMD antibody titer in the serum of sheep received SP than in vaccinated sheep without SP ration additive. Depending on these results we can conclude that Spirulina Platenesis has an immune modulatory effect in sheep vaccinated with FMD vaccine suggesting that it can increase the protection rate and immunity duration against the disease infection.
The impact of supplementing thymol, eugenol, and their combination into the diet of growing rabbits on growth traits and hematological parameters under heat stress conditions
Authors: Mohamed Mahmoud , Fathala Mohamed , Elkomy Alaa , Abdullah Hajar , Sahwan Ferial
Published: December 2024

Heat stress poses significant challenges for rabbit production, affecting welfare, growth, and overall performance. In this study, we aimed to evaluate the impact of dietary supplementation with thymol, eugenol, and their combination on the growth parameters and hematological parameters on growing heat stressed rabbits. Sixty weaned V-line rabbits, aged 35 days with an initial body weight of 654 ± 10 g were distributed into five groups: C- (control diet under thermoneutral conditions), C+ (control diet under heat stress), T (250 mg/kg thymol supplemented with the control diet under heat stress), E (250 mg/kg eugenol supplemented with the control diet under heat stress), and ET (250 mg/kg thymol + 250 mg/kg eugenol supplemented with the control diet under heat stress).The results revealed that both the thymol alone and thymol-eugenol mixture in rabbits' diet contributed to the highest body weight and weight gain, showing significant improvements during specific weeks of the trial due to their phytogenic substances properties (P<0.05). Moreover, the thymol-eugenol combination resulted in increased feed intake (P<0.001) in the heat-stressed groups, indicating a potential synergistic effect. Phytogenic supplementation effectively enhanced WBCs count, neutrophil, and lymphocyte percentage, alongside the restoration of MCV, MCH, and RDW-SD values to levels similar to those of non-stressed rabbits. In conclusion, dietary phytogenic compounds in thymol and eugenol could mitigate the harmful effect of heat stress in growing rabbits
Preparation and evaluation of inactivated Newcastle virus vaccine with new adjuvant (EOLANE 150)
Authors: Abdelmoneam Mahmoud , Ali Zeinab , Shaheen Hala , Soliman Reem , Saad Mohamed , Elsafty Mounir
Published: December 2024

Newcastle disease virus cause one of the most damaging viral diseases in poultry industry worldwide. D-VII strain of Newcastle virus was prepared using three different oil adjuvants i.e. Eolane-150, paraffin oil and Montanide ISA 71. Humoral Immune response and potency of all the vaccinated and control groups after single vaccination was evaluated in specific pathogenic free (SPF) birds through Haemagglutination inhibition test and challenge test. In present study, results of Haemagglutination Inhibition Test conducted on serum samples of three vaccinated and one control groups indicated that the group vaccinated with montanide ISA 71 showed highest level of antibodies titer (8.30 log2) on 4th week post vaccination. While the highest antibodies level recorded in groups vaccinated with Eolane-150 and paraffin oil adjuvanted were (7.60 log2, 6.70 log2) respectively. All the vaccinated groups with montanide ISA 71, Eolane 150, paraffin oil showed (100%, 95% and 90%) respectively when challenged with virulent NDV (D-VII strain ) at 4th week post vaccination. vaccines prepared with Eolane-150 and Montanide ISA 71 oil adjuvant had no change in color, no phase separation and no liquefaction up to 90 days post manufacturing at 4°C and 25°C. On the other hand, vaccine with paraffin oil adjuvant showed phase separation of aqueous and oil phase days post manufacturing. As a summary we concluded that three prepared vaccines are not significantly different. Eolane 150 oil adjuvant somewhat similar to Montanide ISA 71 oil adjuvant as provides higher protective antibody titers and protects against challenge by virulent NDV in contrast with vaccine prepared from paraffin oil adjuvant. Also, Eolane 150 economically is a cheaper formulation and accessible adjuvant compared to Montanide ISA 71 and consumes a little time and simple effort during vaccine preparation process compared to paraffin oil adjuvants.
Effect of Different Marketing Age on Productive and Economic Efficiency of Broiler Chickens
Authors: Hamed Amira , Gamil Zienab , Sallam Eman , Mohammed Liza
Published: December 2024

Broiler marketing decisions and the length of the production cycle are critical when considering productivity and profitability. Therefore, the purpose of this study was to evaluate the effects of different marketing ages on the Ross chickens' growth performance, carcass characteristics, and economic efficiency. A total of 120 one-day-old Ross chicks were received, weighted, and then divided by chance into five treated groups (each with four subgroups and six chicks per subgroup) according to marketing age (D1:33 days; D2: 35 days; D3: 37 days; D4: 39 days and D5: 41 days). Our findings declared that changes in broiler marketing age were associated with highly significant changes in final body weight, body weight gain, average daily gain, relative growth rate, feed intake, feed conversion rate (FCR), feed cost, total cost, total cost per day, total return per day, and total return. The highest values were recorded with the highest marketing age (41 d.), while the lowest values of the same parameters were observed with the lowest marketing age (33 d.). A significant increase in dressing percentage was observed as broiler age progressed from 33 to 39 days at the market; afterward it decreased. D1 had significantly the highest net profit per kilogram live body weight, profitability index, and benefit-cost ratio compared to D5, along with a significantly lower FCR, which indicates a better economic efficiency of lower marketing age. So we concluded that birds marketed at 33 d. can be used efficiently to reduce expenses and obtain better FCR and profitability than birds marketed at 41 d.
Monitoring adverse blood transfusion reactions at a tertiary care hospital in Haryana: A haemovigilance study
Authors: Kushwaha Anugya , Bhardwaj Vinod , Singh Pawan , Kumar Naveen , Budania Navin , Ahuja Siddharth
Published: December 2024

Background:
Hemovigilance stands as a fundamental necessity for the safe transfusion practice. It is an essential component of quality management in transfusion.

Aim:
Study was conducted with the primary objective to determine the incidence of adverse transfusion reactions occurring in blood/ blood product recipients and secondary objectives were to access the imputability and severity of those adverse transfusion reactions.

Methods:
This was a cross-sectional, observational study conducted in the blood bank department of SHKM GMC Hospital, over a period of 1 year from October 2022 to September 2023. All patients admitted to the clinical wards and ICUs of different clinical departments who were transfused with whole blood/blood components and reported to have transfusion reaction during or after transfusion of blood components were enrolled in the study. The only exclusion criteria were the participants not willing to participate in the study.

Results:
The incidence of adverse transfusion reactions in the current study is 0.73%. Majority of ATR incidence was seen with whole blood 2.41% as compared to other blood components. Allergic reactions accounted for 40.91%, followed by febrile non-hemolytic transfusion reactions 33.33%. Most of adverse transfusion reactions in the study were non-severe (Grade-1) 84.85%. The imputability assessment of majority of the transfusion reactions was in probable 65.15% and possible category 24.24%.

Conclusion:
The current study highlights the significance of transfusing blood and blood components judiciously. Blood bank SOPs regarding transfusion should be strictly follow to prevent errors while transfusion.
Exploring the impact of an innovative student question-making activity in competency based medical curriculum: A comparative study from two batches
Authors: Dhar Dipak , Shrivastava Abha
Published: December 2024

Background:
Active learning is a pivotal component of the Competency Based Curriculum reforms worldwide. Its advantages in terms of learning outcomes, student motivation and engagement are well known. But implementation of active learning across the world remains low. This study aimed to introduce a new teaching-learning method which is driven by the philosophy of active learning and builds upon the benefits of student question-making.

Aim:
The study was done to assess the effectiveness student-generated Scenario-Based Questions (SBQs) on their knowledge and how it impacted their overall academic performance. The study also sought to understand the dynamics of implementing this method and gauge how the students received this method of learning.

Methods:
An analytical cross-sectional study was conducted among two consecutive batches of MBBS students in their Phase 1 in Physiology. Participants were divided into study and control groups. The study group underwent learning sessions by question-making (structured, subjective type Scenario-Based Questions), while the control group received traditional small group teaching. Knowledge was compared by within-group analysis of pre-post questionnaire scores using paired t-test. Between-group analysis was done using independent sample t-test for academic performance as recorded from the aggregate marks obtained our of 100 in pre-university examination. Feedback was collected from students on a Likert scale. P-value <0.05 was considered statistically significant.

Results:
Students in the study group demonstrated significantly higher post-test scores and better academic performance compared to the control group. Positive feedback regarding the method's effectiveness and acceptability was received from participants.

Conclusion:
The SBQ-based question-making activity method is an effective tool for enhancing medical students' learning and academic performance. It fosters deeper understanding, critical thinking, and engagement. This method can be incorporated into medical education to promote student-centred learning and improve overall outcomes and eventually transform them into life-long learners.
Vasorelaxant effects of hydro-ethanol leaves extract of Adansonia digitata on different models of conductance and resistance vessels in rat
Authors: Sene Mbaye , Diouf Ibrahima , Ba Awa , Ndiaye Mamadou , Ba Fatoumata , Toure Maimouna , Diaw Ndeye , Kane Modou , Sarr Mamadou , kerth Val
Published: December 2024

Background:
Adansonia digitata leaves are utilized in traditional medicine for the treatment of hypertension in Senegal.

Aim:
The objective of this study was to evaluate the vasorelaxant effects of the hydroethanolic leaf extract of Adansonia digitata (ADF) on rat mesenteric, carotid, femoral arteries, and thoracic aorta.

Methods:
Rat mesenteric, carotid, femoral arteries, and thoracic aorta rings were suspended in organ chambers for recording changes in isometric forces. They were then balanced for 45 minutes to a basal tension of 1 g and contracted with a KCl solution (80 mM) to verify the integrity of the arteries. After washing with Krebs solution and returning to a basal tension of 1 g, the rings were contracted again with phenylephrine (1 μM) until the concentration plateau was reached, then released by adding acetylcholine (ACh, 1 μM). Vessels were considered to have functional endothelium when acetylcholine induced a relaxation greater than 90%. In some experiments, the endothelium was removed before contraction with phenylephrine and concentration-relaxation responses to ADF were measured.

Results:
ADF produced 91.43%, 72.08%, 68.89%, and 71.32% relaxation, respectively, in superior mesenteric, carotid, femoral arteries, and thoracic aorta at 10 µg/ml in endothelium-intact arteries pre-contracted with phenylephrine.

Conclusion:
Adansonia digitata induces vasodilation, which may explain its antihypertensive effect and its use in traditional African medicine.
Assessment of mind mapping as a tool for retention of learning in microbiology among phase II medical students: A mixed methods study
Authors: Kaup Soumya , Gurumurthy Rekha , Srinivas Roopashree
Published: December 2024

Background:
Medical curriculum is vast and retaining information is a challenge. Mind mapping is a tool that can facilitate retention of information by actively involving the learner in the learning process.

Aim:
Current study was conducted to assess the effectiveness of mind mapping as a tool for knowledge retention and revision; and to explore the perceptions of students regarding its utility.

Methods:
A concurrent mixed-methods study was conducted in the Microbiology department involving 73 phase-II medical students. Students were divided into two groups by stratified random sampling ensuring equal distribution of slow, moderate and fast learners. Group-A consisting of 36 students was trained on the usage of mind maps. After a didactic lecture, group-A used mind mapping whereas group-B, consisting of 37 students used conventional reading for learning and revision. Mean scores of the two groups in MCQ-based test at 1 week and 1 month was compared and statistical significance assessed using independent-sample t-test. Perception of mind mapping among the students was assessed using a questionnaire and Focus Group Discussions and presented in the form of themes.

Results:
Our study showed significant difference in MCQ scores at 1 week (p<0.01) showing that mind mapping is a useful tool for knowledge retention. Most of the students perceived mind mapping as a useful tool and opined that it facilitated knowledge retention, saved time during revision and improved comprehension.

Conclusion:
Mind mapping aids in retention of knowledge and can be a useful supplementary tool facilitating the students to effectively assimilate the vast medical curriculum.
Efficacy and safety of metformin immediate release versus extended release in drug naive patients with type 2 diabetes: A randomized controlled trial
Authors: Farookh Syed , Kamath Laxminarayana , R Raveendra
Published: December 2024

Background:
Type 2 Diabetes is marked by varying degrees of insulin resistance and a progressive decline in the function of pancreatic β cells, this resulting in compromised insulin secretion leading to hyperglycemia and subsequent complications.

Aim:
This study aims to evaluate the efficacy and safety of Metformin Immediate Release (IR) versus Metformin Extended Release (ER) in patients with Type 2 Diabetes.

Methods:
In this parallel group, comparative, open label clinical study, patients (n = 70) were assigned to two groups: 35 patients were randomized to receive Metformin IR 500 mg tablet orally twice daily and the remaining 35 patients to receive Metformin ER 1000 mg tablet orally once daily for 12 weeks. Fasting Plasma Glucose (FPG), Postprandial Plasma Glucose (PPG) and Glycated Hemoglobin (HbA1c) were recorded at the start and end of study.

Results:
There was a significant decrease in FPG, PPG and HbA1c glycemic parameters from baseline to week 12 in both Metformin IR and Metformin ER groups but the difference was not statistically significant between the groups. Incidence of adverse effects were less reported with extended-release formulation. All patients tolerated both the formulations of metformin with good compliance.

Conclusion:
In this study both Metformin Immediate Release (IR) and Extended Release (ER) formulations demonstrated similar efficacy in improving glycemic control in drug naïve patients with type 2 diabetes. However, the ER formulation exhibited a superior safety profile, characterized by a reduced incidence of adverse effects, thereby could improve drug compliance.
Genetics, Human Capital Formation and the Intergenerational Transmission of Socioeconomic Status
Authors:   , van Alten Sjoerd Jan Dick
Published: December 2024

This thesis explores how genetics influences socioeconomic traits, such as education, income, and health outcomes. It contributes to the methodology of measuring the genetic underpinnings of such traits, and makes an applied contribution by assessing the role that genetics plays in the intergenerational transmission of socioeconomic status.
Chapters 2 and 3 study how the large genetic data sets that are used in genomewide association studies (GWAS) of human behavioral traits are subject to selection bias, because respondents participate in such data sets on a voluntary basis. In Chapter 2, I highlight how various estimates from a frequently used large-scale biobank (the UK Biobank) may be misleading due to volunteer bias, how this bias can be mitigated with inverse probability weights, and I give suggestions on how the next generation of biobanks could deal with this problem of volunteer bias.
In chapter 3, I use the weights estimated in Chapter 2 to show that the non-representative sampling of genetic data biases GWAS analyses. Correcting for volunteer bias using inverse probability weights generally increases the effect sizes of SNPs, increases heritability estimates and alters gene tissue expression results for various traits investigated.
In chapter 4, I study the impact of the polygenic index (PGI) for educational attainment (EA) on the socioeconomic outcomes of one's children. Studying this causal impact is made possible through a novel link between the Lifelines Cohort Study and Dutch administrative data. I condition on the sum of grandparental PGIs to isolate exogenous variation in a parent's PGI at the conception of this parent. As a result, the estimated effect of the parent's PGI on their children's outcomes can be causally interpreted. I find that the EA PGI of parents influences their children's education, income, and wealth, once these children have reached adulthood. The effects are relatively large, showing a surprisingly high intergenerational persistence of one's EA PGI. I show that this high persistence can be understood because two mechanisms mediate the effect of a parent's PGI on children's socioeconomic outcomes. The first occurs at conception of the child, due to the transmission of genetic material from the parent to the child. The second mechanism is environmentally mediated: the genes of a parent influence the environment in which children grow up. Hence, even genes that are not transmitted to the child impact socioeconomic outcomes of children. This “genetic family environment” effect is especially large for wealth-related outcomes, contributing to the large intergenerational persistence of wealth.
The Story of Prophet Ibrahim as a Model of Example in the Qur'an
Authors: . Mahfud , Syayfi Sohib , Dewi Nurul Auliya , Anshorullah Arich H
Published: December 2024

Example is one of the most effective educational methods to instill positive values in a person. However, in the modern era with easy access to information, exposure to various cultures and figures can have a negative impact if imitating a figure who has bad morals. Islam as a religion of rahmatan lil 'alamin, provides many exemplary examples to be learned, one of which is the Prophet Ibrahim 'alaihis salam who is nicknamed as the Father of the Prophets and the Lover of Allah. This study aims to examine the example of the Prophet Ibrahim 'alaihis salam as depicted in the Qur'an. The method used is qualitative literature research. The research data is in the form of verses of the Qur'an and their interpretations, then analyzed and interpreted. The results of the study show that there are many examples of the story of the Prophet Ibrahim 'alaihis salam that can be adopted in daily life. The story of the Prophet Ibrahim 'alaihis salam provides a valuable lesson on how to be a devout Muslim and behave nobly. His example can be a source of inspiration for Muslims to improve the quality of faith and morals.
Moral Criteria for Couples in the Story of the Prophet Moses and the Madyan Woman in Surah Al-Qaṣaṣ: 22-28
Authors: Haris Abdul Rauf , . Mahfud , Bahiy Ni’mazzad Al-
Published: December 2024

The benchmark that is considered by shari'a in choosing a spouse is in terms of religion and morals, because these two things can show the nobility of the couple. The selection of a partner based on religion and morals has been applied first by the Prophet Moses in QS. Al-Qaṣaṣ. In the letter, it is explained that Moses chose Shafura (the youngest son of Shu'aib) because the Prophet Moses already knew his morals. Likewise, Shu'aib chose Moses after seeing the religion and morals of the Prophet Moses. The purpose of writing this thesis is to explain the moral content of the Prophet Moses and Madyan women in QS. Al-Qaṣaṣ: 22-28. The method used by the author is a qualitative method with a type of library research that is descriptive and analytical. The primary sources used by the author include Tafsir At-Tahrīr wa At-Tanwīr, At-Tafsir Al-Munīr, Tafsir Al-Qur'ān Al-Karīm by Al-'Uthaymeen. The conclusion of this study is that the author found several moral values in the Prophet Moses, including: tawakal to Allah, compassion for the weak, patience, strong and trustworthiness, keeping promises and perfecting them. The moral values that the author gets from Madyan women are: filial piety to parents, murū'ah (maintaining self-honor), shyness, intelligence and gentleness in speaking.
The Concept of Repentance in the Tafsir of the Qur'an Al-Azhim: A Survey According to Ibn Kathir
Authors: Syayfi Sohib , Hariyanto Didik , . Taufik
Published: December 2024

Man is a creature prone to sin, but with repentance, every mistake and sin can be washed away. Repentance is a process of changing from bad conditions to good desired by Allah the Exalted, which is accompanied by charity and charity. The concept of repentance is an integral part of Islamic sharia which governs the relationship between the slave and the Rabb. This study aims to elaborate the interpretation of verses on repentance and its concept according to Ibn Kathir, using thematic research methods. The conditions for receiving repentance include stopping sins, feeling remorse, wanting not to repeat sins, asking forgiveness, and restoring the rights of others if involved in violations of rights. The conclusion of this study is that repentance has the meaning of "return and regret" when it comes to sin. The concept of repentance according to Ibn Kathir is that every individual who commits a sin, then regrets his deed, confesses the sin, and immediately repents and performs pretext, will be accepted repentance by Allah.
Overview of the Level of Activity Daily Living of the elderly who have chronic diseases in the Geriatric Polyclinic of the State General Hospital
Authors: Ni Wayan Suetri  , Sang Ayu Ketut Candrawati  , Ni Ketut Citrawati
Published: December 2024

Introduction: The increase in the elderly population will of course be accompanied by an increase in the risk of suffering from chronic diseases which can accelerate functional decline and reduce the ability of the elderly to carry out important activities in daily living Activities of Daily Living (ADL
Objectives:    The aim of this study was to obtain a more comprehensive picture of the level of ADL independence in elderly people with chronic diseases
Methods:  This type of research is descriptive with a cross-sectional study design. The research sample of elderly people who had chronic diseases was 63 elderly people selected using consecutive sampling. The research instrument uses the Barthel Index.
Results:  The results of the study showed that of the 63 elderly people, the majority of the 39 elderly people (61.9%) who had chronic diseases experienced a mild level of dependence in carrying out daily living activities
Conclusions:  Chronic diseases can affect the functional abilities of elderly people in living their daily lives. The importance of educating the elderly and their families about chronic disease management, providing support to increase independence, as well as developing intervention programs that can improve the elderly's ability to carry out Activities of Daily Living (ADL).
The Effect of Giving Krispi Potato Skin on Increasing Hemoglobin Levels in Adolescent Girls at Salafiyah Syafi'iyah Islamic Boarding School Sukorejo Situbondo
Authors: Ifa Nurhasanah
Published: December 2024

Introduction: An adolescent is someone who experiences rapid growth and development. Not infrequently, information that says that adolescents often experience several diseases, especially anemia. anemia is characterized by Hb levels below normal. Usually those who often experience anemia are adolescent girls, therefore it is necessary to prevent and overcome anemia by increasing Hb levels.
Objective: the purpose of this study was to determine the effect of giving crispy potato skins on increasing hemoglobin levels in adolescent girls at the Salafiyah Syafi'iyah Islamic Boarding School in Sukorejo Situbondo.
Methods: the method used in this study is a pre-experiment one group test, conducted on adolescent girls aged 13-22 years as many as 25 people.
Result: the results of this study are independent variables, namely age (0.227), knowledge (0.517) and provision of potato skins (0.999) have no effect on increasing Hb levels.

Conclusions: the conclusion of this study is to minimize the level of error when conducting research so that the results obtained are maximized and in accordance with the desired research objectives.
Treatment Modalities, Analgesic Use, Cancer Stage, and Cancer Location on Symptom Clusters in Head and Neck Cancer Patients
Authors: Ika sari Wyssie
Published: December 2024

Introduction: Head and neck cancer patients generally have the same symptoms, but the prevalence and severity can vary. The prevalence and severity of symptoms in a cluster are related to the overall symptom experience. The prevalence and severity of symptoms in a cluster can be related to the patient's health and illness state. Objectives: This research aims to determine the relationship between treatment modalities, analgesic use, cancer stage, and cancer location on symptom clusters in head and neck cancer patients. Methods: The method used is analytical observational with a cross-sectional approach. The sample inclusion criteria were as follows: head and neck cancer without metastatic disease to the brain, cooperative and good at communicating, and age 18-70 years. Meanwhile, the exclusion criteria are not completing the questionnaire due to critical condition, mental disorders, death, and patient going home. The sampling technique used was consecutive sampling, consisting of 111 patients at Dr. Kariadi Central General Hospital of Semarang. Data analysis using Spearman Rho. Results: The relationship between the significance values ​​of the treatment modality variables for sickness and gastrointestinal symptom clusters, the use of analgesics for gastrointestinal symptom clusters, the location of cancer for emotional symptom clusters, and the stage with symptom clusters is <0.05. The research results also show that several variables also have a significance value of > 0.05. Conclusions: Good identification of treatment modalities, use of analgesics, cancer stage, and cancer location is expected to be able to overcome symptom clusters in head and neck cancer.
The Care Giver Lived Experience in Caring for Elderly With Palliative Conditions
Authors: Ni komang Sukra andini , Sang ayu ketut candrawati
Published: December 2024

Introduction: Elderly is the final stage of the human development cycle. Every year the number of elderly people increases in Indonesia in the Bali area based on the population census. The prevalence of the number of elderly people from 2021 to 2022 increases. According to a survey by the Indonesian Medical Gerontology Association (PERGEMI), as many as 24.6% of the elderly population (seniors) in Indonesia have a history of chronic disease. In the condition of the elderly who are unable to take care of themselves fully, they need a caregiver or companion who is often called a caregiver, the role of a caregiver is as a provider of nursing care to the patient. Objectives: This study aims to describe of the care giver's experience in caring for elderly people with palliative conditions.
Methods: Data were collected using the face-to-face individual in deep interview, with semi structure interview questions.
Results: The results of this study by using interviews and observations from 4 participants, 4 themes were obtained that show the Care Giver's experience in caring for the elderly with palliative conditions, namely: (1) End Stage of Life Phase (2) Routine Care (3) Psychological Support (4) Spiritual Support.
Conclusions: The description of the Care Giver's experience is considering palliative conditions as conditions in the End Stage of Life Phase; Daily care focuses on Routine Care; Psychological support is really needed; Spiritual support is really needed. Based on the research results, it can be concluded that elderly people in nursing homes in the final phase of their lived experience worsening conditions between life and death and all their needs are assisted by caregivers. In palliative conditions, all daily needs are fulfilled by the caregiver. The main focus of care for elderly people with palliative conditions is providing psychological support and spiritual supported
Implementation of Maintaining Mobility to Reduce the Risk Falls in Elderly
Authors: Elmaghfuroh Dian Ratna , Haryanti Dwi Yunita , Romadhoni Roza Riska
Published: December 2024

Aging is associated with a decline in the physical and cognitive functions of the human body, which also involves the possibility of age-related diseases. Reduced muscle strength and coordination of the lower extremities, accompanied by decreased gait assurance and balance control, are the results of physical deterioration in the aging body. In decreased physiological function, these disorders lead to a higher risk of falls in the elderly. Maintaining mobility is an effort that can be a preventive measure for falls through physical exercise, meeting nutritional needs, and regular health checks. This study aims to determine the effect of palliative care using a maintaining mobility approach to prevent the risk of falls in the elderly at PSTW Jember. This research design is a pre-experimental quantitative research design with a pretest-posttest group design approach with a total sample of 30 elderly people. This research uses analysis of the Wilcoxon statistical test. The research results showed that elderly people who were at risk of falling had a history of musculoskeletal disease of 33.3%, with a p-value of 0.0001. The implementation of maintaining mobility for the elderly can affect the Morse Fall Scale score. In conclusion, there is an effect of maintaining mobility interventions to reduce the risk of falls in the elderly at PSTW Jember.
The Effect of Earthquake Simulation Animation Videos on The Knowledge And Skills of Earthquake Disaster Preparedness in The 5th-Grade Elementary School Klatak Banyuwangi 2023
Authors: Masroni Masroni , Andrik Hermanto  , Hillary Elsafitra
Published: December 2024

Introduction: Disaster preparedness involves preparing a counter-disaster plan, warning of the disaster, and maintaining resources needed during and after a disaster. The media that can be used by using animated videos can increase knowledge and skills more easily and interestingly for elementary school students.
Objectives: This study aimed to investigate the effect of earthquake simulation animation videos on the knowledge and skills of earthquake disaster preparedness in the 5th-grade Elementary School Klatak Banyuwangi.
Methods: This study used a pre-experimental research plan with a one-group pre-test post-test research design of 56 respondents with a total sampling technique. Then, statistical analysis was done using the Wilcoxon Signed Rank Test from SPSS 16.
Results: Before being given an animated video, they had a knowledge level of scores, most of them as much as 41% in the category of unprepared, mostly 62.5% competent enough for skills. After being given an animated video, knowledge increased to 64.3% with ready criteria, and skills increased to 82.1% with very competent criteria. With a significance value of p=0.000<0.05, there was a significant Effect of Earthquake Simulation Animation Videos on the Knowledge and Skills of Earthquake Disaster Preparedness in 5th grade elementary School Klatak Banyuwangi 2023.
Conclusions: Applying knowledge and skills in earthquake disaster preparedness can be done early, starting from elementary school, one of which is by using animated video media, which is expected to be more easily understood, interesting, and can be applied in everyday life.
Effect Of Chlorine Application In Simple Water Filtration Process On Iron Content Reduction In Groundwater
Authors: Gultom Tati Baina , Sapta Wibowo Ady
Published: December 2024

Chlorine Ca(OCl)2 is another compound of chlor that can also remove various kinds of organic and inorganic substances, where these substances have oxidizing and reducing abilities.
Two-valence iron (Fe2+) contained in groundwater is caused by the dissolution of water that seeps into the soil, so that the groundwater contains ferrous bicarbonate [Fe(HC03)2], where the water when used will harm the user.
This experimental study aims to determine the effect of the dose of chlorine as an oxide in a simple water filtration process on reducing iron (Fe) levels in groundwater using water samples from the borehole complex of the Tanjungkarang Health Polytechnic, Department of Environmental Health. The research was conducted in the laboratory of the Environmental Health Department of Tanjungkarang Health Polytechnic, by making several doses of chlorine treatment in 1,000 ml of raw water, namely P1 = 0.5 gr, P2 = 1.0 gr, P3 = 1.5 gr, P4 = 2.0 gr and P0 without chlorine as a control.
The treatment process is carried out by dosing chlorine, stirring (V = 70 rpm, t = 5 minutes), settling (t = 5 minutes) and filtering with a sand filter (0 = 0.1 - 1.5 mm, h = 20 cm) at a discharge of 100 ml / minute.

The research results from 5 experiments showed the following experimental results of chlorine 0.0 gr (70.00%); 0.5 gr (84%); 1.0 gr (90%); 1.5 gr (97%) and 2.0 gr (98%). The statistical test used is the analysis of variance, where the hypothesis of the experimental results is rejected, which means that there is a significant difference in the effect of dosage as an oxidizer in a simple water filtration process on reducing iron (Fe) content in groundwater. Further research is needed for maximum results
THE EFFECT OF ELDERLY EXERCISES ON REDUCING PAIN IN THE ELDERLY AT THE AL-ISLAH ELDERLY CENTER
Authors: Hahar Enos Umbu mada , Sih Ageng Lumadi  , Sismala Harningtyas
Published: December 2024

Introduction: Elderly or old age is the final stage of human life development, starting from the age of 60 years and above. The elderly experience a decrease in the ability of the body's organs to repair themselves or change or maintain normal function. Gymnastics for the elderly is light exercise that can be done anywhere, and is a sport that is not included in the heavy exercise category, so it can be applied to the elderly.
Objective: to determine the effect of exercise on reducing pain in the elderly at the Al-ishlah elderly home.
Method: The research design used was pre-experimental using one class pre test-post test design. The total sample of 22 respondents was included in this research. The Wilcoxon test was used in this research with the SPSS program.
Results: test results p value = 0.000. This result shows a significant value smaller than the specified value, namely 0.05 (p≤0.05). Based on these results, Ha was accepted and Ho was rejected, so it was concluded that Ha was accepted, meaning that there was an influence of elderly exercise on reducing pain in the elderly at the Al-Islah Elderly Home.

Conclusion: There is an influence of elderly exercise on reducing pain in the elderly with a pain score scale of mild, moderate and severe
The Effectiveness of Diabetes Self-Management Education on Changes in Blood Sugar Levels in Type II DM Patients at the Klatak Public Health Center, Banyuwangi Regency
Authors: Efendi Achmad , Lidia Hastuti  , Wuriani
Published: December 2024

Introduction: Providing self-skills education and training to improve the ability of type II DM sufferers to carry out self-care management (DSME) including 8 important components and applying peer support to increase motivation and improve their health, avoid complications to early death.
Objective: This study aimed to determine the effectiveness of Diabetes Self-Management Education on changes in blood glucose levels in patients with type II DM at Banyuwangi Regency in 2023.
Method: Experimental research with the design of True Experimental Pretest pos-ttest control group design. The population were all type II DM patients who were treated regularly at the Klatak Public Health Center. A sample of 24 respondents in the control and 24 in the intervention groups used the MSD sample size formula. Respondents in this study were examined pre- & post-test venous plasma blood glucose levels. The sampling technique used is an RCT. Data analysis used SPSS 21 for Windows statistical T-test.
Result: The paired T-test results indicated that the P-value for the intervention group was less than 0.05, specifically 0.000. It means Ha is accepted. So, the blood glucose levels differ before and after undergoing DSME with the Peer Support Group method. Then, with a significance value of 0.015 being less than 0.05, it can be inferred that there is a noteworthy difference. Statistical test results of the N-gain score in the intervention group were 50.3% in the Less Effective category, while in the control group was -4.4% in the Ineffective category.
Conclusion: There is a significant mean difference between the two groups. The N-gain score test results in the intervention group were higher than control group. It is hoped that the implementation of DSME with the Peer Support Group will be more systematic, sustainable, and focused on changing behavior.
OS MEIOS PROBATÓRIOS DE ILÍCITOS ELEITORAIS LIGADOS À INTELIGÊNCIA ARTIFICIAL E O RITO DA REPRESENTAÇÃO POR PROPAGANDA IRREGULAR NO DIREITO PROCESSUAL ELEITORAL DO BRASIL
Authors: Café Antônio Eduardo Oliveira Damascena
Published: December 2024

Os novos dispositivos os quais disciplinam o uso de inteligência artificial, acrescentados à Resolução do Tribunal Superior Eleitoral que regulamenta a Propaganda Eleitoral, traz, em sua redação, ilícitos que devem, segundo o processo eleitoral brasileiro, ser alvos de processo judicial de representação, rito célere e que não permite dilação probatória. Por isso, se faz necessário tratar e pré-constituir os meios de provas possíveis para se ingressar com a referida pretensão na justiça, bem como para comprovar a existência ou não do ilícito, uma vez que a olho nu é muito difícil determinar se um conteúdo é ou não manipulado por tecnologias artificiais, dada sua computadorizada precisão. O estudo traz como referencial teórico a teoria da prova eleitoral proposta por José Jairo Gomes dentro da contenda judicial eleitoral. Para tanto, foram realizadas revisões bibliográficas e uso de ferramentas tecnológicas que poderão incrementar os meios de prova. Os resultados foram as proposições de plataformas e técnicas testadas e verificadas, por este estudo, bem como a compatibilidade com o regramento pátrio, para adequar o arcabouço probatório às inovações tecnológicas da inteligência artificial.
Cyclodextrin- based nanoparticles for pharmaceutical Application as an Antimicrobial Agents: A Review
Authors: Yadav Abhishek , Gupta Ashutosh , Prajapati Indrakesh , Singh Riya , Mishra Shweta
Published: December 2024

Nanotechnology is considered essential in the field of pharmaceutical applications for treating drug
delivery problems as well as antimicrobial therapy and Cyclodextrin nanoparticles are noted to have an exceptional
versatility playing a major role. This review will focus on these nano systems enhance drug solubility, stability and
targeting (critical issues for poor bioavailable drugs or the management of problems like antimicrobial resistance)
Then, possible future directions for the biocompatibility and surface modification strategies that could improve
their therapeutic benefits will be discussed as well safety. Apart from pharmaceutical applications, cyclodextrin
nanoparticles have been used for environmental remediation including water treatment or novel application as
knowledge transfer and gas separation new area etc. Abstract This review elucidates the isolated interdisciplinary
growth of PAS in health professions education and seven other domains, showcasing their potential to enhance
understanding for both researchers and practitioners interested in how best to leverage their instrumentalize
affordances. Hence, cyclodextrin nanoparticles might facilitate such processes to be used more routinely and
predictably in the future development of health-related products and applications.
KEY WORDS: Cyclodextrin based nanoparticle, drug delivery, controlled release, Targeted therapy
LIBRARY MANAGEMENT SYSTEM
Authors: JANNATHUL FIRTHOUS, MRS.I.A. , KUMAR P.PRAVEEN , KRISHNAN, NAVANEETHA , ARJUN S.MOHANA , KUMAR T.NITHISH
Published: December 2024

This is a website created for online library management
system. In this website we are mentioned all authors and
books name and you can see and buy all types of books
which are available in the library. You can search and buy
all types of books which are available in the library. You
can see and get the books that you need in our website. In
this website if you order a book which is not delivered the
admin can immediately check the status of order and
deliver to your location as soon as possible. This website
is created for manage books in library.
Key Words: admin, book insert, Library Management.
The development of learning media in virtual classroom on topics of Thai performing arts
Authors: Rittibul Pravit , Boontonglek Manoch , Orachun Riswan , Ngerndang Artitaya , Boonsong Panurat
Published: December 2024

This research aims 1) to develop and test the effectiveness of learning media on Virtual Classroom on topics of Thai performing arts 2) to compare the pre- and post-learning achievements. 3) to study the satisfaction of students towards the learning media of Virtual Classroom on topics of Thai performing arts for Grade 10 students, Thammasat Khlong Luang Wittayakom School, thirty-six people were randomly selected. The research tools consisted of Learning Media Virtual Classroom on topics of Thai performing arts, pre-test and post-test media quality assessment form, satisfaction assessment form. Statistics used were mean standard deviation consistency Index of E1/E2 and t-score. The research findings were as follows: 1) The learning media development process for the Virtual Classroom on topics of Thai performing arts according to the ADDIE Model on Thai Traditional Performing Arts consisted of 4 types: 1. Khon (The Mask Dance) 2. Drama performances 3. Dance and dance performances 4. Native performances Teaching through learning media, Virtual Classroom on topics of Thai performing arts, efficiency was 82.31/85.56 which was higher than the criteria of 80/80. 2) The learning achievement of students after learning was higher than before which is different 3) Students' satisfaction after using the learning media Virtual Classroom on topics of Thai performing arts had the mean value of 4.56, at the highest level.
Network meta-analysis comparison of Hydrus, Istent microinvasive glaucoma surgery implants, and phacoemulsification for handling open-angle glaucoma
Authors: Anjaswari Niska Ayu , Primitasari Yulia , Wungu Citrawati Dyah Kencono , Komaratih Evelyn , Sasono Wimbo , Sulistiawati Sulistiawati
Published: December 2024

This study aims to analyze the comparative effectiveness of two Microinvasive Glaucoma Surgery (MIGS) devices, Hydrus and iStent, in combination with phacoemulsification in patients with open-angle glaucoma. The protocol for this network meta-analysis registered in PROSPERO under registration number CRD42023404273. Literature search was conducted following PRISMA guidelines. RCTs were retrieved from multiple databases based on inclusion and exclusion criteria. Evaluated parameters included intraocular pressure, visual acuity, the number of postoperative anti-glaucoma medications, and complications. Mean probability for each treatment was obtained using SUCRA. Ten selected articles originating from America and Europe with varying follow-up periods. SUCRA analysis shows that the combination of Hydrus and phacoemulsification ranks highest in reducing IOP at 92.38%, compared to the combination of iStent and phacoemulsification at 56.99%, and phacoemulsification only at 0.62%. The best outcomes for post-intervention BCVA ≥ 20/40 are reported in the SUCRA diagram (63.88%), as well as for the best post-intervention medication use (85.5%) and minimal complications (86.41%), which were observed in combination of iStent and phacoemulsification. The Hydrus combination intervention showed the greatest reduction in IOP, while the iStent combination more effective in improving visual acuity and reducing postoperative anti-glaucoma medication use and had the fewest overall postoperative complications. This study highlights that MIGS interventions, particularly Hydrus and iStent combined with phacoemulsification, offer significant benefits and show more effective compared to standalone phacoemulsification.