bluuebunny/crossref_metadata_2025 huggingface dataset:
Problems in diabetic retinopathy treatment and management during the COVID-19 pandemic
Authors: Öncül Hasan , Alakuş Mehmet Fuat
Published: November 2020

Purpose: The aim of this study is to determine the problems occurring
during the COVID-19 pandemic period in patients treated with
intravitreal (IV) injection for diabetic retinopathy, and to provide
recommendations for treatment management in these patients. Methods:
Twenty-nine eyes of 17 patients were included in this prospective,
observational study. The frequency of hospital visits, treatments
performed, and detailed ophthalmological examination findings, including
optical coherence tomography findings and glycated haemoglobin (HbA1c)
values, were recorded in the period before the COVID-19 pandemic. During
the COVID-19 pandemic period, the detailed ophthalmological examination
findings and HbA1c values were noted after the patients who had delayed
their routine control time (>90 days) applied to the
hospital. New treatments were planned according to the current
situation. Results: Seventeen patients who were diagnosed with diabetic
macular edema were included in the study; 10 were female (58.8%) and
seven were male (41.2%). The mean time interval between following
visits was 45.52±5.85 days during the pre-pandemic period, but it
increased to 110.41±13.47 days during the COVID-19 pandemic period
(p<.001). Visual acuity (LogMAR) was 0.44±0.36 in the
pre-pandemic period and 0.76±0.48 during the COVID-19 pandemic period
(p=.003). Central macular thickness was 300.10±85.56 µm in the
pre-pandemic period and it increased to 387.10±144.48 µm during the
COVID-19 pandemic period (p=.007). In three patients, complications of
diabetic retinopathy that could not be cured by medical treatment
developed and surgical treatment was recommended. Conclusions: Delays in
the treatment of diabetic retinopathy may cause permanent impairment in
visual functions. The COVID-19 pandemic has caused an increase in the
hospital visit intervals of patients, and this situation has resulted in
disruptions in the follow-up and treatment of patients with diabetic
retinopathy. Alternative diagnosis and treatment practices are needed in
order to manage these and similar processes smoothly.
Clinical outcome after bioprosthetic aortic root replacement: A Meta-Analysis and Microsimulation model
Authors: Arabkhani Bardia , Etnel Jonathan , Vriesendorp Michiel , Valen Richard van , Lansac Emmanuel , Brakel Thomas van , Bogers Ad , takkenberg hanneke
Published: November 2020

Background and aim of the study This study aims to provide an overview
of clinical outcome after bioprosthetic aortic root replacement and
lifetime event-risk estimates of mortality and valve-related events, and
the potential effect of type of prosthesis used. Methods A systematic
literature search was conducted between January 2000 and August 2019.
Inclusion criteria: aortic root replacement in adults. Data were pooled
by inverse-variance weighting and entered a microsimulation model to
calculate lifetime event-risk and (event-free) life expectancy. Results
Of 2.106 publications, 31 were included (N = 5.227 patients, 74%
stentless valves). Mean age was 65.4 years (74% male). Pooled early
mortality was 5.5% (95% CI: 4.3-7.2%). During follow-up (mean 4.1
years, total 22.706 patient-years), late mortality was
4.8%/patient-year and reoperation 0.9%/patient-year.
Linearized-occurrence-rates for thromboembolism, endocarditis, and
hemorrhagic events:1.2; 0.9 and 0.5 %/patient-year; no significant
difference between stented and stentless prosthesis. Translating into a
60-year-old patient, an estimated life expectancy of 14 years (general
population: 22 years) and lifetime risks of thromboembolism,
endocarditis and reintervention of 21%, 13%, and 8%, respectively is
expected. Conclusions The study shows impaired survival and a notable
lifetime risk of valve-related events after bioprosthetic aortic root
replacement. The risk of thromboembolism is prominent, especially during
earlier follow-up, suggesting higher risk of thromboembolism early after
operation. Type of prosthesis, stented or stentless, is not associated
with higher valve-related events. Moreover, this study could be used as
a benchmark to compare outcome with other aortic root replacement
procedures.
Pan-genome analysis of coronaviruses derived from major of canine and feline
Authors: Thi Hai Ha Pham , Nguyen Thanh Luan
Published: November 2020

Coronaviruses (CoVs) are a well-known cause of severe enteric,
respiratory, and systemic disease in a wide range of animals and in
humans. To understand the route of disease origin and viral transmission
in companion animals, a comparative pan-genomic analysis of coronavirus
sequences originating from major felines and canines were conducted. The
average nucleotide identity (ANI) is a rapid procedure for assessing the
very close antigenic relationship between feline CoV (FCoVs) and canine
CoV (CCoVs) and ANI-based phylogenetic tree that clustered CoVs
according to their respective host species. While pan-genomic analysis
demarcated strains clearly. The distribution of the clinical isolates
all across the categories in the hierarchical phylogenetic model enabled
the visualization of their original ecological niche rather than their
isolation source, as infections are extremely rare events and
evolutionary dead-ends. In polymorphism analysis, we found seven
accessory gene clusters common to the FCoV/CCoV category clade,
including pantropic strains, that perform functions supporting their
pathogenicity. In addition, the gene presence/absence among FCoVs and
CCoVs would provide very valuable information on species-specific
control measures against CoV disease, such as the selection of good
markers for differentiating new species from common and/or pantropic
isolates. Also, the virulent FCoV strains were grouped with human CoV
strains NL63 and 229E confirming hypotheses stating that cats are highly
susceptible to HCoVs, while dogs have low susceptibility to the virus.
In conclusion, the combined analysis allows for better phylogenetic
resolution and the implication of virus origins, recombination, and
virus–host interaction, as well as biomarkers.
Landscape and spatial patterns of avian influenza virus in Danish wild birds, 2006-2020
Authors: Kjær Lene , Hjulsager Charlotte , Larsen Lars , Boklund Anette , Halasa Tariq , Ward Michael , Kirkeby Carsten
Published: November 2020

Avian influenza (AI) is a contagious disease of birds with zoonotic
potential. AI virus (AIV) can infect most bird species, but clinical
signs and mortality vary. Assessing the distribution and factors
affecting AI incidence can direct targeted surveillance to areas at risk
of disease outbreaks, or help identify disease hotspots or areas with
inadequate surveillance. Using virus surveillance data from passive and
active AIV wild bird surveillance, 20062020, we investigated the
association between a range of landscape factors and game bird release
and the presence of AIV. Furthermore, we assessed potential bias in the
passive AIV surveillance data submitted by the public, via factors
related to public accessibility. Lastly, we tested the AIV data for
possible hot and cold spots within Denmark. The passive surveillance
data was biased regarding accessibility to areas (distance to roads,
cities and coast) compared to random locations within Denmark. We found
significant effects of variables related to coast, wetlands and cities
for the passive and active AIV surveillance data (P< 0.01),
but found no significant effect of game bird release. We used these
variables to predict the risk of AIV presence throughout Denmark, and
found high-risk areas concentrated along the coast and fjords. For both
passive and active surveillance data, low-risk clusters were mainly seen
in Jutland and northern Zealand, whereas high-risk clusters were found
in Jutland, Zealand, Funen and the southern Isles such as Lolland and
Falster. Our results suggest that landscape affects AIV presence, as
coastal areas and wetlands attract waterfowl and migrating birds and
therefore might increase the potential for AIV transmission. These
findings have enabled us to create risk maps of AIV incidence in wild
birds and pinpoint high-risk clusters within Denmark. This will aid
targeted surveillance efforts within Denmark and potentially aid in
planning the location of future poultry farms.
Axin, the classic scaffold protein of Wnt/β-catenin signalling as a potential drug-target for vitiligo
Authors: Chen Duozhi , Fan Shirui , Lu Xueying , Jing Chenxu , Zang Deng , Yang Bijuan , Cai Jieyun , Wang Yiting , Zhang Xinfang , Li Lin , Aisa Haji Akber , Hao Xiaojiang
Published: November 2020

Background and Purpose: Humans have been fighting vitiligo for centuries
but still being inferior due to the lack of efficiency drugs and
therapies. While some research has implied the therapeutic potential of
Wnt/β-catenin signalling on curing vitiligo but correlation mechanism is
not clear and no Wnt-specific anti-vitiligo drug has been reported.
Here, We identified how vitiligo could be treated by regulating Wnt and
two lead compounds of new anti-vitiligo drugs have been found.
Experimental Approach: Wnt agonists were rational synthesized and then
be evaluated their effects on vitiligo in B16 cells and C57B/L mouse.
Furthermore, Co-IP and Site-directed mutagenesis were employed to
indicate the mechanism and the target of the compounds. Key Results:
HCJA121 and HCJA404 could significantly promote the synthesis of
melanin, restore the pigmented function of skin, and improve the
symptoms of vitiligo. Mechanism studies indicated that HCJA121 and
HCJA404 target the DAX domain of Axin by binding to LYS781 and LEU784
then potentiate the Axin-LRP6 association and eventually promoted
melanogenesis. Conclusions and Implications: These findings imply an
alternative regulatory mechanism of melanogenesis and the Axin protein
could be a new target for anti-vitiligo agents which reveal a
therapeutic strategy for vitiligo. Besides, HCJA121 and HCJA404 may
represent potential compounds for vitiligo treatment.
Magic and Disbelief in Carolingian Lyon
Authors: Bailey Michael D.
Published: November 2020

The Middle Ages are often associated with credulity, especially toward magic, compared to modern Western society, which is often regarded as thoroughly disenchanted. Yet not all medieval people believed unhesitatingly in all magical practices. The early ninth-century Carolingian archbishop Agobard of Lyon described a remarkable system of weather-magic widely believed by people in his diocese of which he was completely skeptical. He justified his disbelief through references to biblical texts, but this study argues that his disbelief was grounded in his own encounters with and investigations of these magical practices, and focused only on certain elements within them.
Power and Conflict in Russia’s Borderlands. The Post-Soviet Geopolitics of Dispute Resolution
Authors: Levinsson Claes
Published: November 2020

Abstract: Power and Conflict in Russia’s Borderlands. The Post-Soviet Geopolitics of Dispute ResolutionClaes Levinsson (Uppsala University) reviews Power and Conflict in Russia’s Borderlands. The Post-Soviet Geopolitics of Dispute Resolution by Helena Rytövuori-Apunen.
O MENINO DO GOUVEIA A HISTÓRIA REAL QUE INSPIROU O PRIMEIRO CONTO HOMOERÓTICO BRASILEIRO DE 1914
Authors: Costa Valmir
Published: November 2020

O primeiro conto homoerótico do Brasil, “O Menino do Gouveia”, foi lançado em fevereiro de 1914. Trata-se do sexto volume da coleção “Contos Rápidos” da revista erótica O Rio Nu (1898-1916), voltada para homens heterossexuais. Porém, O Rio Nu inicia uma narrativa pilhérica e erótica com um tal “Gouveia” a partir de julho de 1906 até o lançamento do conto em 1914. Tal personagem real é retratado em O Rio Nu como um homem mais velho com tara por sexo anal. Para além da ficção, o conto é inspirado em um fato real ocorrido no ano de 1906, envolvendo o tal Gouveia, inclusive, o nome vira gíria e uma lenda urbana no Rio de Janeiro daquele período. Tal descoberta deve-se a uma pesquisa realizada nos diários Jornal do Brasil, Jornal do Commercio e O Paiz, entre maio e julho de 1906, para verificar algumas notícias publicadas sobre o “Gouveia” na Hemeroteca Digital Brasileira, da Fundação Biblioteca Nacional.
A GUINADA PRAGMÁTICA DA LINGUAGEM E “A INVENÇÃO DO COTIDIANO”
Authors: Trombetta Gerson Luís , Soares Fabrício Antônio Antunes
Published: November 2020

O artigo apresenta as características gerais da guinada pragmática da linguagem, de modo especial como aparecem na filosofia de Ludwig Wittgenstein. Apresenta também como as teses centrais da guinada pragmática da linguagem influenciaram a visão de Michel de Certeau sobre a narrativa historiográfica, exposta no seu livro A invenção do cotidiano.  A hipótese é que a maneira como Michel de Certeau dialoga teoricamente com o segundo Wittgenstein abre desafios e perspectivas para a narrativa historiográfica que vão muito além das limitações empiristas.
VISÕES SOBRE O HUMANO: A FRONTEIRA-SERTÃO DO BRASIL MERIDIONAL (1889-1905)
Authors: Pereira de Lima Aranha Bruno
Published: November 2020

Este artigo consiste numa proposta de análise de relatos decorrentes das expedições brasileiras que se dirigiram à fronteira com a Argentina entre 1889 e 1905, onde hoje se localiza a província de Misiones (Argentina) e as regiões sudoeste do Paraná e oeste de Santa Catarina e Rio Grande do Sul, no lado brasileiro. Nossa análise busca ampliar a ideia de fronteira apenas como uma linha demarcatória para pensá-la como uma borderland, idealizada pelos viajantes como um sertão a ser ocupado formalmente pelo Estado. Com isto, percebemos que o olhar manifestado sobre as populações sertanejas desta região interiorana era permeado por diversas nuances, sobretudo, por se tratar de um espaço transnacional onde ainda não existia uma fronteira demarcada de fato.
RESEARCH ON THE GOVERNANCE OF GOVERNMENT NETWORK PUBLIC OPINION IN THE AGE OF BIG DATA
Authors: Chunjuan Wang , Xiao Zhu
Published: November 2020

With the popularization of mobile terminals, information is becoming more and more unimpeded, along with the advent of the era of big data. It brings both opportunities and challenges to the governance of government network public opinion. Using the literature research methodology and the case analysis, combing the research results of domestic and foreign scholars, this paper analyzes the current situation of the network public opinion governance, concludes that having initially built a big data platform for network public opinion and realized the transformation from managing to governing network public opinion, the government strengthens the awareness of the rule of law of network public opinion gradually. Also, it is believed that the government has not fully grasped the opportunity brought about by the big data, with idea, technology as well as ethical dilemma remaining. Finally, from the three aspects it provides development strategies for the government to create a healthy and green network public opinion ecology.
A RANKING FOR THE SUSTAINABLE DEVELOPMENT GOALS FOCUSING ON THE 5PS
Authors: Dumpe Agris L. , Guevara Arnoldo De Hoyos
Published: November 2020

Moving strategically toward the 2030 Agenda for Sustainable Development, the UN organized a Sustainable Development Solutions Network (UNSDSN) and a Platform (HLPF) in order to harness the so-called Data Revolution that could help to achieve systemically the 17 Goals, by attaining local and globally the corresponding targets. For this purpose, there is a need to keep joining efforts and know-how to develop an appropriate framework and roadmap. This paper represents a contribution for monitoring the SDG based on the 5Ps People, Planet, Prosperity, Peace and Partnership; by using data from the Iberoamerican Foresight Network Observatory (ORIBER).
A ERA DO BIG DATA: PRINCIPAIS IMPLICAÇÕES SOBRE SEGURANÇA E PRIVACIDADE E AS NOVAS TECNOLOGIAS CAPAZES DE AUXILIAR PROCESSOS INVESTIGATIVOS E DETECÇÃO DE FRAUDES EM TEMPO REAL
Authors: Rosini Filho Alessandro Marco , Rosini Alessandro Marco , Palmisano Angelo
Published: November 2020

With the great expansion in the volume of data created in recent years, coupled with the speed at which the most distinct information is generated from multiple and different origins, this work developed through qualitative method, based on a review and descriptive analysis of main publications made on the topic Big Data, based on security and privacy, in order to understand and analyze the different thoughts on the subject. We sought to submit the concepts involving this phenomenon termed as Big Data, as well as expose the issues and challenges surrounding the security and privacy of data stored and used by organizations that adopt technologies capable of extracting determining values on existing data, detecting that there are still many aspects that effect which must be carefully evaluated by the organizations that have this type of technology, or aims to implement it. In this concern, it was of interest in this research and check to see that these new technologies can make a decisive contribution to security optimization engine of technological environments and own technology itself, can bring important advances with regard to the prevention and detection fraud, more efficiency and agility in investigative processes and add more strategic intelligence with respect to public safety, aimed at combating crime.
Symptoms of Heat Stress in Tropical and Subtropical Regions on Farm Animals
Authors: Habeeb Alsaied Alnaimy Mostafa
Published: November 2020

The thermal relief regions for maximum animals are ranged 4 °C and 25 °C. In tropical and subtropical countries ambient temperature surpasses 25° C and animals undergo high environmental temperatures. Most physiological and biochemical variations in animals could take place to care for essential cell functions in contradiction of stressful conditions and to certification a fast retrieval from modest hypothermic destruction. Animal performance is reduced due to extreme variations in biological purposes affected by heat-stress conditions.
Microbiological Properties of Probioticated Kununzaki Drink Enriched with Cocoa Powder
Authors: Adeniran H. A. , Adeniyi D. M. , Taiwo K. A.
Published: November 2020

Kununzaki- a popular and an affordable West African cereal-based beverage was enriched with cocoa powder and subjected to ‘probiotication’ with ‘probiotic’ lactic acid bacteria and subsequently investigated for sustained viability of the microbes and ability to suppress growth of food-borne bacteria. This study enumerated the different microbes in enriched kununzaki drink before and during storage, identified the isolated microbes and assessed the viability of the ‘probiotic’ lactic acid bacteria (LABs) in the drink and determined the antagonistic effect of the LABs on two selected food-borne pathogens. This was with a view to enhancing the health giving attributes of affordable kununzaki, which is already a popular beverage in Nigeria. Laboratory results revealed total viable bacteria, lactic acid bacteria and mould counts to range from 4.69 – 8.76, 6.45 – 9.74 and 6.04 – 8.77 log cfu ml-1, respectively. The microorganisms isolated were identified as: Bacillus brevis, B. Badius, B. polymyxa, B. macquariensis, B. pantothenticus, Staphylococcus aureus, S. epidermidis, Serratia marcescens, Lactobacillus delbrueckii, L. fermentum, L. plantarum, L. casei, Aspergillus niger, and Curvularia affinis. ‘Probiotic’ lactic acid bacteria were viable (69.75 log cfu ml-1) at the end of four weeks of storage. The viabilities of Lactobacillus fermentum which were 9.75 and 9.58 log cfu ml-1 at ambient and refrigerated temperatures, respectively were higher than those of other lactic acid bacteria species. The same organism was found to be active against one of the tested food-borne pathogens, Escherichia coli as evident in the diameter of zone of inhibition on plate and broth culture analyses. The study concluded that Lactobacillus fermentum could be effectively used for ‘probiotication’ of kununzaki enriched with 20% cocoa powder and the resulting product exhibited potential of checkmating a food-borne bacterial strain and by implication has the potential of promoting the health of consumers. The product was also found to be microbiologically stable for 4 weeks of storage at ambient and refrigeration temperatures.
Characterization of The Nutritional Properties of Sorghum Composite Flours Using Different Food to Food Fortification Approaches
Authors: Mugalavai Violet K. , Oyalo Josiah O. , Onkware Augustino O.
Published: November 2020

Intervention using blended composite flours can reduce malnutrition in sub Saharan Africa. Prevalence of protein-energy malnutrition among the vulnerable children has necessitated research on cost effective food product development like food to food fortification of common staples like sorghum. An investigation was carried out on the nutritional properties of selected sorghum composite flours for the production of porridge for both home and industrial applications. In this study, composite flours V1 to V4 were made from sorghum, maize, grain amaranth, baobab and butternut at different rations; V1-(42.5:22.5:5:15:15),V2-(22.5:42.5:5:15:15), V3-(32.5:32.5:5:15:15) and V4-(65:0:5:15:15) were compared against composite flours AV1 to AV4 made from sorghum, cassava, chickpea, orange fleshed sweet potatoes (OFSP) and baobab; AV1-(42.5:22.5:5:15:15) AV2-(22.5:42.5:5:15:15), AV3-(32.5:32.5:5:15:15) and AV4-(65:0:5:15:15). Standard methods were used in determining the chemical characteristics of the composite flours. Composite flour formulations were based on Concept4â creative software. Results on proximate composition indicated a significant (p < 0.05) difference in moisture content of the control composite (V5) and the other composite flours with the moisture content ranging from 9.1% to 12.1% in V5 and V3 respectively. Carbohydrates were the most abundant nutrient in the composite flours 66.0 to 72.7% in V1 and V5 respectively, followed by fat 5.5% (AV3) to 9.2% (AV1), protein 5.1 (AV2) to 8.6% (AV4), crude fibre 1.5 (V2) to 4.3% (V5), and ash 1.4 (AV1) to 2.8% (AV4). The total energy ranged between 359.25 kcal (V4) to 379.94 kcal (V1) however, these values were not significantly different (p > 0.05). Zinc, calcium and magnesium concentration were significantly different (p <0.05) between the sorghum-maize-grain amaranth-baobab-butternut, on one hand and sorghum-cassava-chickpea-OFSP-baobab composite flours on the other. The concentrations of phosphorus and Iron were not significantly different (p > 0.05). Correlation analysis revealed significant negative correlation between crude protein and fibre (-0.512, p ≤ 0.001) and crude protein and iron (-0.386, p ≤ 0.047), whereas crude protein and magnesium had a significant positive correlation (0.455, p ≤ 0.017). The results indicate that both categories of flour composites have the potential to improve nutritional status of consumers. Thus, consumption of V1 and V4 composite flours with a protein content of 8.1% and 8.6% maybe encouraged for children aged 6 - 59 months who need products with good nutritional composition for proper growth and development.
Chromosome HeatMap in CDK Patients as Defined by Multiregional Sequencing on Illumina MiSeq Platform
Authors: Fazaludeen Mohammad F. , Warille Aymen A. , Alaraj Mohd Ibrahim , Nuglozeh Edem
Published: November 2020

Renal failure and kidney disease are major concerns worldwide and are commonly coupled to diseases like hypertension, diabetes, obesity, and hypercholesterolemia. We undertook this study to explore the scope of genetic spectrum underlying the physiopathology of end-stage renal disease (ESRD) using whole exome sequencing (WES) on genomic DNA (gDNA) from 12 unrelated patients in younger ages. We have performed WES on 12 patients in stage of ESRD and analyze the FASTQ data through GATK pipeline. Here, we report for the first time a novel approach of establishing the severity and the magnitude of a disease on different chromosomes and associated karyotypes using chromosome Heatmap. The chromosome Heat will provide us with a road map to narrow down mutations selection leading us to SNPs characterization. Our preliminary results presented in the form of chromosomes HeatMap prelude our ongoing works which consist in identifying and characterizing new genes involved in the problem of renal diseases, results that depict the magnitude of the uncovered genes mutations and their biological implications related to the genome of these patients.
Radiation Induced Defects and Thermoluminescence Characteristics in Eu, Dy and Eu/Dy Doped-Quartz Sol-Gel by 2 Gy Beta and 2 MeV ⁴He⁺ Irradiations
Authors: Khamis Fawzeia , Arafah D.-E.
Published: November 2020

Thermoluminescence (TL) of pure and Eu3+ and Dy3+ doped synthesis quartz was synthesized and their ion beam and thermoluminescence properties were investigated. The as prepared, doped and co-doped quartz and the effects of imparting 2 Gy beta dose and 2MeV 4He+ ion beam irradiation is investigated. The basic model proposed and can explain our observations is that, the dominant signals from the as prepared material arise from the incorporation of the transitions within the RE dopants enhanced by the intensity from the intrinsic or host defect sites within the synthesis quartz network. The complex shape TL glow curves indicate that irradiation causes major distortions to the lattice with the incorporation of extrinsic impurities and RE doping processes, induce perturbations and alter the energy levels pattern of the free ions and assigned transitions probabilities in a manner that that depends on the dopants, their concentrations and the host material. The larger Eu ions stabilize the emission more than that of the Dy ions. The TL peak temperatures are commonly correlated via charge transfer processes and scale with the ions size, in such a manner that the close proximity (or shallow traps) allows lower temperature electron release, whereas the more distant variants (deep traps) are less distorted, but are still able to couple to the higher energy orbitals of the Eu ions.
Pemberdayaan Lokal Masyarakat Kelurahan Wonolopo Kecamatan Mijen Kota Semarang Melalui Pengembangan Desa Agrowisata
Authors: Junaedi Sony , Hayati Endah Dwi , Muslimah Muslimah
Published: November 2020

Kelurahan Wonolopo merupakan desa wisata yang telah ditetapkan menjadi wisata Kota Semarang. Perpaduan antara keindahan alam, kehid
Reflexões para o ensino de língua portuguesa na educação básica
Authors: Santos Gisely Storch do Nascimento , Andrade Fabio Santos de
Published: November 2020

É amplo o debate acadêmico no que se refere ao ensino de língua portuguesa orientado pelas práticas de linguagem. No presente trabalho buscou-se compreender quais são os objetivos do ensino de língua portuguesa frente aos documentos basilares, sendo eles os Parâmetros Curriculares Nacionais e Base Nacional Comum Curricular, bem como quais os caminhos metodológicos possíveis para atender aos pressupostos normativos e teóricos para o ensino de linguagem nas escolas.  Para coleta de dados foi realizada a análise documental e a pesquisa bibliográfica para compreensão de quais seriam os pressupostos para o ensino de linguagem nas escolas, bem como quais as metodologias possíveis. Como resultado da pesquisa, percebeu-se a necessidade do trabalho com os gêneros textuais em sala, apresentando-se algumas possibilidades de organização metodológica para o trabalho com esses gêneros textuais.
Los costos de la cárcel
Authors: Bernal Fabián
Published: November 2020

El contexto carcelario se debe concebir como un orden social desde el cual se ejerce control poblacional, a través de diversos mecanismos, estos implican una maximización de estrategias de vigilancia, donde las diferentes formas de control convergen en el disciplinamiento constante de las subjetividades. Estos mecanismos hacen que la cárcel funcione como una maquina sustentada por quienes la habitan. Memorias de las cárceles argentinas, colombianas y de estadounidenses son ejemplos de esta modalidad de control, sin embargo, pese a que sus dinámicas de funcionamiento interno son diferentes, no escapan a una dimensión económica del control poblacional, donde las personas privadas de su libertad son el insumo básico para el funcionamiento de la máquina, y las destinatarias de las consecuencias subjetivas de la misma. Este ensayo se basa en memorias que dan cuenta de la vivencia de quienes fueron parte e insumo de dicha maquinaria, quienes desde sus recuerdos muestran un retrato del significado y costos del encierro más allá de las fronteras.
Derroteros fundamentales de la cuestión de los principios en el pensamiento jurídico occidental del siglo XX
Authors: Monzón Alejandro González
Published: November 2020

El presente trabajo tiene como objetivo presentar los derroteros fundamentales que ha asumido la cuestión de los principios en el pensamiento jurídico occidental del siglo XX. En este sentido, se identifican y desarrollan en sus aspectos esenciales cinco tendencias sobre el tema, a saber: los principios desde el discurso ontológico-jurídico; los principios desde el discurso de la teoría de las normas jurídicas; los principios desde el discurso de la metodología de la aplicación del Derecho; los principios desde el discurso de la teoría de los derechos fundamentales; y los principios desde el discurso de la argumentación jurídica.
Tierra abandonada
Authors: Muñoz Lorena , Marina Franco Carballo
Published: November 2020

El trabajo propone un abordaje de las construcciones sociales y pensamientos sobre la distribución del territorio, advirtiendo que suelen trasladarse a conflictos académicos, ideológicos y políticos, que muchas veces parten de falsas dicotomías entre el concepto de derecho a la propiedad privada versus el derecho al hábitat. Concluyen sus autores que el Estado no puede mantenerse ajeno a estar realidad, debe revalorizar su rol de regulador de los derechos de propiedad. Y tal regulación se manifiesta, poniendo en práctica políticas públicas que incluyan los diferentes dispositivos e instrumentos existentes para combatir el suelo ocioso.
Teletrabajo, formas de organización, problemas y desafíos
Authors: Correa Francisco , Moltrazio Carolina
Published: November 2020

El aislamiento alteró rotundamente nuestra forma de vida y aceleró debates que teníamos pendientes en distintos planos. Algunos nuevos. Otros, como el teletrabajo, que tienen algunos años y que responden a múltiples factores. Buscamos hacer algunas aproximaciones conceptuales y analizar el impacto que tienen las nuevas formas de producción sobre la forma de organización del trabajo, así como los desafíos jurídicos y sindicales que se disparan.  La historia de la humanidad ha demostrado que con la evolución de las formas empresariales y de los procesos productivos se han dispuesto y/o diseñados nuevas herramientas de trabajo, nuevas formas de consumo, nuevas formas de estudio, nuevas formas de vincularnos, nuevas formas de familia, nuevas formas de organización gremial y política. Este devenir exige una mirada crítica para entender a qué responde el fenómeno del teletrabajo en tanto nueva modalidad de contratación. Así como también para pensar, proyectar y resolver las distintas dificultades que se presentan en materia gremial política (para adaptarnos a una nueva forma de organización que altera nuestras condiciones de trabajo) y en materia normativa (para reglar una nueva realidad laboral). Al respecto, compartiremos las nociones fundamentales del nuevo régimen legal del contrato de teletrabajo.
La astucia de la Corte Suprema de Justicia de la Nación: argumentos para el rechazo o para la declaración de certeza pretendida respecto del art. 30 del Reglamento del Senado de la Nación
Authors: Arias Gerónimo
Published: November 2020

El trabajo analiza el fallo de la CSJN en la causa “Fernández de Kirchner, Cristina en carácter de Presidenta del Honorable Senado de la Nación s/ acción declarativa de certeza”, del 24/04/2020. Para el autor, la decisión comentada versa sobre un debate jurídico de profunda raíz política. Por esta razón, cree que el derecho, como producto de su tiempo, ha dado un resultado positivo y acorde a las necesidades que la pandemia nos exige, receptando las imperiosas demandadas de un contexto imprevisible. Ello es así, toda vez que esta sentencia, sin comprometerse más allá de lo necesario, lo hizo de manera suficiente para facilitar el camino al Poder Legislativo y que éste cumpla su mandato constitucional, aún en las condiciones excepcionales en las que la presentación de la Presidenta del Senado fue realizada.
El certiorari positivo: el avance hacia la jurisdicción estratégica de la Corte Suprema de Justicia de la Nación para definir una agenda judicial racional
Authors: Perícola María Alejandra , Lauhirat Santiago
Published: November 2020

En este trabajo se analiza –a partir de los debates suscitados por la reforma judicial entre los cuales se incluye la creación de un “Consejo Consultivo para el Fortalecimiento del Poder Judicial y del Ministerio Público”- la transformación de una jurisdicción reglada por parte de la CSJN hacia una “apelación discrecional”, para lo cual se torna necesaria la incorporación y profundización del instituto procesal conocido como certiorari positivo. Para este fin, se analiza en primer lugar la apelación reglada, su traspaso hacia una apelación discrecional por parte de la CSJN. En tercer lugar se realiza un análisis constitucional del art.280 del Código Procesal Civil y Comercial de la Nación y finalmente una reflexión sobre la utilidad práctica para la selección de casos estratégica al incorporar el certiorari positivo en el marco de una reforma judicial.
La trata de personas: la codificación de un delito entorpecido por un lenguaje poco preciso
Authors: Marina Lisé Sofía
Published: November 2020

Durante años, la trata de personas, a pesar de considerarse uno de los delitos más importantes y antiguos de la sociedad, ha sido pasada a un segundo plano en la codificación de nuestro código penal dejando como consecuencia una redacción inconsistente e incompleta. Y es que resulta incomprensible cómo es que un delito que atenta a los principales derechos humanos pueda ser pasado desapercibido a lo largo de la historia penal y social de nuestro país, y que haya comenzado a tomar relevancia la necesidad de un reparo social y legislativo recién en el siglo XXI.
El ocio como anti-derecho
Authors: De Viola Ana María Bonet , Saidler Yael Selene , Piva Esteban
Published: November 2020

Artículo de reflexión jurídica. Este artículo fue redactado en el marco del Proyecto de Investigación “Derechos humanos y economía. Relaciones y tensiones entre los derechos sociales y ambientales y el orden jurídico-económico transnacional”, dirigido por Ana María Bonet de Viola y financiado por la Universidad Católica de Santa Fe, Argentina (2019-2022). Los autores realizan un especial reconocimiento a Federico Ignacio Viola que, a partir de su café filosófico acerca del “Elogio de la pereza”, ha inspirado la temática del presente artículo.
Acuerdos de emergencia
Authors: Sánchez John A. Carlin , Trillo Verónica Susana
Published: November 2020

En el siguiente trabajo, nos proponemos analizar las Acordadas 2, 3, y 9 de la Cámara Federal de Casación Penal, con la impronta de hacer explicitas las razones dadas por parte de este tribunal respecto a las cuestiones referentes a la situación de las mujeres en cárceles en el contexto de la pandemia COVID-19. Esto es, detallar cuáles son las medidas de protección adoptadas y, además, cuáles deberían ser los procedimientos a seguir toda vez que se requiera hacer efectiva alguna protección de derechos y garantías en el ámbito carcelario, respecto a mujeres privadas de su libertad, mujeres embarazadas o con hijos a cargo, haciendo una distinción respecto de aquellos niños/as que se encuentren o no alojados en prisión. Para este último supuesto, nos valdremos del análisis de los argumentos de dos fallos resueltos por la Cámara Federal de Casación Penal, en el período del aislamiento preventivo y obligatorio, tomando como muestra dos casos en los que se resolvió de manera divergente.
El rol de los y las juristas frente a las prisiones y el COVID-19
Authors: Gusis Gabriela
Published: November 2020

La realidad de las prisiones de América Latina, y el mundo entero, podríamos afirmar, presentan un escollo ético frente a la propagación de la pandemia en tanto, aunque no todas las prisiones se encuentran en las condiciones de hacinamiento que en gran medida sí hay en América Latina, muchas acarrean problemáticas de híper encarcelamiento, y otras tantas, aunque no cuentan con las mismas condiciones de detención deterioradas como las de nuestros márgenes, llevan consigo los males de cualquier institución total, lo que impone problemas específicos que se evidencian con mayor medida en medio de esta situación, pues la propagación de enfermedades en contextos de encierro estatal resulta ser claramente más alarmante.
Introducción al estudio de la Historia Constitucional
Authors: Moreno Guillermo Raúl
Published: November 2020

A la “historia” se la ha definido de múltiples maneras desde los tiempos más lejanos, pero seguramente todas esas posibles definiciones coincidirán en que estamos en presencia de un tipo de investigación sobre hechos ocurridos en el pasado. Pues, ya desde muy antiguo el término fue utilizado como sinónimo de “narración de los hechos humanos”.
Sustituyendo el futuro
Authors: De Alto Bruno Pedro
Published: November 2020

Se discute el mecanismo de las compras públicas de tecnología como herramienta del Estado para el desarrollo económico y sus posibilidades como promoción para la innovación. Se analiza el modelo de compras públicas clásico y se propone impulsar la Compra Pública de Tecnologías para la Innovación, como una estrategia válida, acertada y útil para el desarrollo nacional. Se trata de un mecanismo que se establece cuando una entidad pública aprueba un pedido de un producto o sistema que no existe en ese momento, que requiere el desarrollo de tecnología nueva o mejorada para poder cumplir con los requisitos demandados por el comprador. Para su implementación se discute la necesidad de establecer normativas específicas para lograr el fomento a este tipo de iniciativas desde distintos niveles del Estado. También se analizan las oportunidades que da la misma gestión pública, y se presentan algunos ejemplos que se están desarrollando durante la actual gestión de la Autoridad de Cuenca Matanza Riachuelo (ACUMAR).
Comunicación pública de la CyT, ¿en el fondo del ropero?
Authors: Murriello Sandra
Published: November 2020

Parece indiscutible que la comunicación pública de la ciencia y la tecnología resultan centrales en medio de la pandemia de COVID-19 que nos atraviesa. Sin embargo, ha quedado en evidencia que el complejo de CyT no tiene capacidad de respuesta comunicacional acorde a las necesidades actuales. En este artículo se reflexiona sobre esta situación a la luz de las prácticas habituales de comunicación instaladas en la comunidad científica. Se resalta la necesidad de poner en valor esta actividad en pos de una producción científico tecnológica que responda a las demandas de la comunidad que la sostiene.
Las vacunas como bienes sociales
Authors: Corvalán Dora
Published: November 2020

La Argentina pasó de contar con uno de los Calendarios Nacionales de Vacunación más completos del mundo, a tener durante los últimos años un faltante de vacunas para atender a la población. En este trabajo se analizan, por un lado, los cambios ocurridos en la producción de vacunas a nivel internacional, con la consolidación monopólica de un grupo de compañías farmacéuticas multinacionales. Por otro lado, se describe la situación en Argentina, su interrelación con el mercado internacional y los actores involucrados. Se propone una estrategia integral para abordar el desarrollo y producción de vacunas, aprovechando la experiencia y las capacidades científico tecnológicas con que cuenta el país. Se sugieren algunas recomendaciones en relación al mercado de vacunas global y el surgimiento de la COVID y se dejan abiertos una serie de interrogantes a resolver, para poder lograr el acceso de toda la población a este bien social.
Otro estilo científico y tecnológico es posible
Authors: Red PLACTS
Published: November 2020

En junio de 2020 fue creada la Red de Pensamiento Latinoamericano en Ciencia, Tecnología y Sociedad (Red PLACTS). Conformada por integrantes del sector científico, tecnológico y universitario, impulsa una agenda que ponga el conocimiento, los recursos y el complejo CyT en proyectos destinados a resolver necesidades y problemas de nuestra sociedad. Se propone participar e incidir en las decisiones que se toman en la gestión de los organismos de CyT, contribuyendo con propuestas e ideas que aporten a construir un proyecto de país popular, igualitario, democrático, soberano, solidario, con perspectiva feminista y desde una mirada federal. Rescata y recupera en proyectos y acciones concretas los aportes de lo que fue históricamente el PLACTED (Pensamiento Latinoamericano en Ciencia, Tecnología, Desarrollo y Dependencia). En este primer documento se describen las características principales de la dinámica tecnocientífica dominante a nivel global y se presentan algunas propuestas para impulsar un estilo científico tecnológico propio en nuestro país y la región.
Ursula Ganz-Blättler. “Signs of time: Cumulative narrative in broadcast television fiction”
Authors: Verhoeven Marcel
Published: November 2020

TV series are one of the very few ‘traditional’ media formats that continue to thrive in the current media landscape. In Europe, the format of TV series (i.e. serial audio-visual fictional narratives) has been surging for some time in terms of numbers of suppliers and consumers, as well as in shares of distributors’ offerings and consumers’ media use. Homegrown high-end original productions have become ‘calling cards’ for suppliers active in the European market(s). Subscription-based, pay-per-view, and advertising-based networks, as well as public service suppliers order and finance serial fiction. International players like Netflix, HBO, Sky, and Amazon invest in original (co-) productions in many countries. From a media economic perspective, the market entry of more and more ‘big tech’ and conglomerate players into the production and distribution of TV series is another indicator of the importance of the product TV series. The success of the format warrants extensive investigation. Nevertheless, compared to, e.g., cinema, ‘new’ media, and political communication, the attention of scholars in communication/media science and other disciplines still seems surprisingly modest, particularly in Europe. Some noteworthy European works on fictional TV series are Schlütz (2016), Redvall (2013), Gormász (2015), and the scientific journal Series – International Journal of TV Serial Narratives (series.unibo.it). Ursula Ganz’s work Signs of Time was accepted as a habilitation thesis in 2009, and an adapted form was published in 2018. The thesis thus represents somewhat of a European premiere in discussing in great detail and depth what the term ‘(audiovisual) cumulative narrative’ entails and how the central feature of accumulation impacts the analysis of narrative as communication and reflective stance.
Zukunftswerkstatt der Ulrich Saxer-Stiftung zum Thema «Media Labs»: Schickes Label oder modernes Arbeiten in der Kommunikationswissenschaft?
Authors: Schweizer Corinne
Published: November 2020

Media Labs: Ist das nur ein schickes Label oder steht dahinter eine moderne Form der Arbeitsorganisation für die kommunikationswissenschaftliche Forschung? Dieser Frage ging die Zukunftswerkstatt der Ulrich Saxer-Stiftung nach, die am 23. Oktober 2020 an der Universität Zürich stattfand. Das Ziel der am IKMZ angesiedelten Stiftung ist es, den publizistik- und kommunikationswissenschaftlichen Nachwuchs in der Schweiz zu fördern. Das tut sie unter anderem durch eine jährliche Werkstatt zu einem aktuellen Thema. Unter der Leitung von Dr. Corinne Schweizer wurde die Werkstatt Corona-bedingt als hybride Variante durchgeführt: Einige Teilnehmende und Referierende sassen im Hörsaal, andere waren online zugeschaltet.
Case report: myxoid atypical fibroxanthoma: a challenging diagnosis of a rare variant
Authors: Stavrinou Nikolina , Papadopoulou Stavroula , Mitropoulou Georgia , Trihia Helen , Provatas Ioannis
Published: November 2020

Background:

Atypical fibroxanthoma is a cutaneous benign tumor of uncertain lineage, occurring more frequently in elder men, in sun-exposed or irradiated skin. It appears as a slowly progressing nodule, and it is treated by total excision. Several histological types have been described including the myxoid atypical fibroxanthoma.

Case presentation:

A 73-year-old male presented at the plastic surgery department for excision of a single hard, centrally ulcerated, nodule on the right side of the scalp, 4.1 cm in maximum diameter growing slowly during the last years. The microscopical examination revealed a circumscribed, cellular tumor developing in the dermis. The cellular population consisted of spindle cells and histiocytes, without a specific growth patern. Moderate cytologic and nuclear atypia were observed, combined with a relatively high mitotic rate. Also, many positive areas of myxoid degeneration detected with periodic acid Schiff and Alcian Blue stains were revealed. Immunohistochemistry showed positivity of the tumor cells for CD10, FXIIIa and focally for CD68, CD117, smooth muscle actin (SMA), and CD99. Tumor cells were negative for all the other assessed markers, including S-100 and Desmin. Ki-67 was 20%. Based on these morphological findings, the diagnosis of myxoid atypical fibroxanthoma was made.

Conclusion:

Atypical fibroxanthoma is a benign lesion, the diagnosis of which may be proved dificult and challenging. Moreover, when we deal with a rare histologic variant, such as the atypical fibroxanthoma with myxoid change, only the strict application of histological criteria combined with the immunohistochemical findings can lead us to the correct diagnosis, excluding malignant, easily recurring, and metastasizing neoplasms.
EFFECTS OF BIOPESTICIDES IN Tetragonisca angustula LATREILLE (HYMENOPTERA: MELIPONINAE) POLLINATORS
Authors: Prescinato de Oliveira Carlos Vinício , Sinópolis Gigliolli Adriana Aparecida , Galhardo Douglas , Moreira Daiani Rodrigues , Ronqui Ludmilla , Santos Simone Aparecida , Arnault Toledo Vagner Alencar , Ruvolo-Takasusuki Maria Claudia Colla
Published: November 2020

Stingless bees Tetragonisca angustula (Latreille) (Hymenoptera: Meliponinae) are pollinators of native and cultivated plants, are therefore in contact with areas contaminated by pesticides. These native bees were evaluated for changes in gene expression of esterase isoenzymes and peptides after contamination by contact with insecticides growth regulators Gallaxy ® EC 100, Natuneem and Azamax after 48, 120, 168 hours, 30 and 60 days. EST-4 presented an increase in relative activity after contamination with Gallaxy ® 100 EC at 6.2 × 10-2 g a.i/mL, Natuneem at 7.5 × 10-5 g a.i/mL and Azamax at 1.2 × 10-3 g a.i/mL after 60 days, 48 h and 60 days, respectively. Inhibition of the relative activity of EST-4 was detected after contamination by the Natuneem at 1.5 × 10-5 g a.i/mLand Azamax at 1.2 × 10-3 g a.i/mL after 48 h and 30 days respectively. The insecticides growth regulators promoted changes in protein synthesis of adult workers of T. angustula resulting in an increase or decrease in the relative intensity of bands, and the appearance of new peptides compared with controls. Changes in protein synthesis have been identified mainly after long period of contamination, 120 and 168 h with the IGRs Gallaxy ® EC 100 (at 0.78 and 1.25 g a.i/mL), Azamax (at 1.2 × 10-3 and 6 × 10-3 g a.i/mL) and Natuneem (at 7.5 × 10-5 and 3 × 10-3 g a.i/mL) and 60 days with Natuneem (at 1.5 × 10-5 g a.i/mL).