bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 1 from Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion
Authors: Li Fengkai , Kitajima Shunsuke , Kohno Susumu , Yoshida Akiyo , Tange Shoichiro , Sasaki Soichiro , Okada Nobuhiro , Nishimoto Yuuki , Muranaka Hayato , Nagatani Naoko , Suzuki Misa , Masuda Sayuri , Thai Tran C. , Nishiuchi Takumi , Tanaka Tomoaki , Barbie David A. , Mukaida Naofumi , Takahashi Chiaki
Published: March 2023

Pathway analysis of genes upregulated by RB depletion in MCF-7 cells.
Supplementary Data from MDM2-Recruiting PROTAC Offers Superior, Synergistic Antiproliferative Activity via Simultaneous Degradation of BRD4 and Stabilization of p53
Authors: Hines John , Lartigue Schan , Dong Hanqing , Qian Yimin , Crews Craig M.
Published: March 2023

Online captions for SI
Supplemental Table 1 from RNA Sequencing of the NCI-60: Integration into CellMiner and CellMiner CDB
Authors: Reinhold William C. , Varma Sudhir , Sunshine Margot , Elloumi Fathi , Ofori-Atta Kwabena , Lee Sunmin , Trepel Jane B. , Meltzer Paul S. , Doroshow James H. , Pommier Yves
Published: March 2023

Gene composite transcript levels for 23,826 genes (fragments per kilobase per million reads, FPKM)
Table S2 from A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT
Authors: Kossenkov Andrew V. , Qureshi Rehman , Dawany Noor B. , Wickramasinghe Jayamanna , Liu Qin , Majumdar R. Sonali , Chang Celia , Widura Sandy , Kumar Trisha , Horng Wen-Hwai , Konnisto Eric , Criner Gerard , Tsay Jun-Chieh J. , Pass Harvey , Yendamuri Sai , Vachani Anil , Bauer Thomas , Nam Brian , Rom William N. , Showe Michael K. , Showe Louise C.
Published: March 2023

Number of samples used on different platforms for training and validation sets
Table S1 from A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT
Authors: Kossenkov Andrew V. , Qureshi Rehman , Dawany Noor B. , Wickramasinghe Jayamanna , Liu Qin , Majumdar R. Sonali , Chang Celia , Widura Sandy , Kumar Trisha , Horng Wen-Hwai , Konnisto Eric , Criner Gerard , Tsay Jun-Chieh J. , Pass Harvey , Yendamuri Sai , Vachani Anil , Bauer Thomas , Nam Brian , Rom William N. , Showe Michael K. , Showe Louise C.
Published: March 2023

Demographics for patients used in the microarray study
Supplementary Data File from Preexisting Commensal Dysbiosis Is a Host-Intrinsic Regulator of Tissue Inflammation and Tumor Cell Dissemination in Hormone Receptor–Positive Breast Cancer
Authors: Buchta Rosean Claire , Bostic Raegan R. , Ferey Joshua C.M. , Feng Tzu-Yu , Azar Francesca N. , Tung Kenneth S. , Dozmorov Mikhail G. , Smirnova Ekaterina , Bos Paula D. , Rutkowski Melanie R.
Published: March 2023

Descriptions of supplemental figure legends.
Figure S1 from A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT
Authors: Kossenkov Andrew V. , Qureshi Rehman , Dawany Noor B. , Wickramasinghe Jayamanna , Liu Qin , Majumdar R. Sonali , Chang Celia , Widura Sandy , Kumar Trisha , Horng Wen-Hwai , Konnisto Eric , Criner Gerard , Tsay Jun-Chieh J. , Pass Harvey , Yendamuri Sai , Vachani Anil , Bauer Thomas , Nam Brian , Rom William N. , Showe Michael K. , Showe Louise C.
Published: March 2023

NanoString platform quality controls
Supplementary Table from Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells
Authors: Schwab Annemarie , Siddiqui Aarif , Vazakidou Maria Eleni , Napoli Francesca , Böttcher Martin , Menchicchi Bianca , Raza Umar , Saatci Özge , Krebs Angela M. , Ferrazzi Fulvia , Rapa Ida , Dettmer-Wilde Katja , Waldner Maximilian J. , Ekici Arif B. , Rasheed Suhail Ahmed Kabeer , Mougiakakos Dimitrios , Oefner Peter J. , Sahin Ozgur , Volante Marco , Greten Florian R. , Brabletz Thomas , Ceppi Paolo
Published: March 2023

List of differentially expressed genes in all analyzed datasets
Supplementary Data Figure 1 from Preexisting Commensal Dysbiosis Is a Host-Intrinsic Regulator of Tissue Inflammation and Tumor Cell Dissemination in Hormone Receptor–Positive Breast Cancer
Authors: Buchta Rosean Claire , Bostic Raegan R. , Ferey Joshua C.M. , Feng Tzu-Yu , Azar Francesca N. , Tung Kenneth S. , Dozmorov Mikhail G. , Smirnova Ekaterina , Bos Paula D. , Rutkowski Melanie R.
Published: March 2023

16S rDNA sequencing of antibiotic and non antibiotic treated mice prior to tumor initiation indicates mice have commensal dysbiosis. A. shows phylum and genus reads, B. shows beta diversity, C. Shows alpha diversity, D. Shows cecal weights
Supplementary Video S2_Vector from Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility, and Metastasis
Authors: Khan Imran , Gril Brunilde , Steeg Patricia S.
Published: March 2023

Endocytosis of pHrodo Red-EGF in vector expressing cells
Supplementary Video S2_NME1_P96S from Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility, and Metastasis
Authors: Khan Imran , Gril Brunilde , Steeg Patricia S.
Published: March 2023

Endocytosis of pHrodo Red-EGF in NME1_P96S (mutant) expressing cells
Figure S4 from LINC00261 Is an Epigenetically Regulated Tumor Suppressor Essential for Activation of the DNA Damage Response
Authors: Shahabi Shandy , Kumaran Vishaly , Castillo Jonathan , Cong Zhengmin , Nandagopal Gopika , Mullen Daniel J. , Alvarado Alexander , Correa Michele Ramos , Saizan Autumn , Goel Riya , Bhat Amrita , Lynch Sean K. , Zhou Beiyun , Borok Zea , Marconett Crystal N.
Published: March 2023

Figure S4. A. Migration of LINC00261 in A549 cell lines. The A549-shLINC00261 stable cell line and A549-shScrambled control were plated on transwell filters and measured by Violet blue staining. Statistical analysis was performed using a paired t-test (p=0.0581). B. Brightfield image of A549-shLINC00261 stable cell line and A549-shScrambled control. Magnification = 40X. Arrows indicate multinucleated cells (~10-15% of total population).
Figure S3 from LINC00261 Is an Epigenetically Regulated Tumor Suppressor Essential for Activation of the DNA Damage Response
Authors: Shahabi Shandy , Kumaran Vishaly , Castillo Jonathan , Cong Zhengmin , Nandagopal Gopika , Mullen Daniel J. , Alvarado Alexander , Correa Michele Ramos , Saizan Autumn , Goel Riya , Bhat Amrita , Lynch Sean K. , Zhou Beiyun , Borok Zea , Marconett Crystal N.
Published: March 2023

Figure S3. Characterization of stable H522-CMV-LINC00261 cell lines. A. qRT-PCR levels of LINC00261 expression in H522 cells transfected with ectopic CMV-LINC00261 and CMV-NEO backbone as the control vector. Three stable cells lines of each construct were generated. B. IGV image of LINC00261 locus (hg19). Blue = BigWig tracks of primary AEC RNA expression. Reads are binned to 30bp windows. Purple = BigWig tracks of H522 cell lines stably selected with either CMV-LINC00261 ectopic expression or CMV-NEO control vector.C. Quantification of in vitro cell migration shown in Figure 2B using T-Scratch Software. Paired t-test was used for statistical significance. D. Gating images of FACS analysis from Figure 2C. Live cells were selected by exclusion of cell debris. Representative images shown.
Supplementary Data from Phosphorylation of SOCS1 Inhibits the SOCS1–p53 Tumor Suppressor Axis
Authors: Saint-Germain Emmanuelle , Mignacca Lian , Huot Geneviève , Acevedo Mariana , Moineau-Vallée Karine , Calabrese Viviane , Bourdeau Véronique , Rowell Marie-Camille , Ilangumaran Subburaj , Lessard Frédéric , Ferbeyre Gerardo
Published: March 2023

Supplementary data contains additional methods and reagents and figures. The figures contain the following information: Supplementary Figure 1 extends figure 1 providing evidence that SOCS1 may interact with hydrophobic motifs present in many transcription factors. Supplementary Figure 2 supports figure 1 showing SOCS1 mutations found in human cancers that affect the SOCS1-p53 interacting motif Supplementary Figure 3 extends figures 1 and 2 providing additional functional characterization of SOCS1 mutants that affect p53 binding. Supplementary Figure 4 supports figure 5 showing SOCS1, p53, and YES1 expression levels in DLBCL. Supplementary Figure 5 supports figure 5 showing a description of patients' samples using to study phospho-SOCS1 levels by cancer subtype and different kinds of phospho-SOCS1 staining in these samples. Supplementary figure 6 supports figure 6 showing SRC family expression in DLBCL according to Oncomine. Supplementary Figure 7 supports figure 6 showing controls for the PLA that shows SOCS1-p53 interaction.
Figure S5 from Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
Authors: Daher Boutaina , Parks Scott K. , Durivault Jerome , Cormerais Yann , Baidarjad Hanane , Tambutte Eric , Pouysségur Jacques , Vučetić Milica
Published: March 2023

Clonogenicity
Figure S4 from Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
Authors: Daher Boutaina , Parks Scott K. , Durivault Jerome , Cormerais Yann , Baidarjad Hanane , Tambutte Eric , Pouysségur Jacques , Vučetić Milica
Published: March 2023

Tumor Growth
Supplementary Data from Activation of the Unfolded Protein Response via Inhibition of Protein Disulfide Isomerase Decreases the Capacity for DNA Repair to Sensitize Glioblastoma to Radiotherapy
Authors: Liu Yajing , Ji Wenbin , Shergalis Andrea , Xu Jiaqi , Delaney Amy M. , Calcaterra Andrew , Pal Anupama , Ljungman Mats , Neamati Nouri , Rehemtulla Alnawaz
Published: March 2023

Cell line authentication
Figure S1 from Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
Authors: Daher Boutaina , Parks Scott K. , Durivault Jerome , Cormerais Yann , Baidarjad Hanane , Tambutte Eric , Pouysségur Jacques , Vučetić Milica
Published: March 2023

Clonogenicity & growth
Video S2 from Contact-Dependent Killing by Cytotoxic T Lymphocytes Is Insufficient for EL4 Tumor Regression In Vivo
Authors: Beck Richard J. , Slagter Maarten , Beltman Joost B.
Published: March 2023

Supplemental Video 2
Supplementary Methods from Contact-Dependent Killing by Cytotoxic T Lymphocytes Is Insufficient for EL4 Tumor Regression In Vivo
Authors: Beck Richard J. , Slagter Maarten , Beltman Joost B.
Published: March 2023

Supplementary Methods
Supplementary Figure6 from Temozolomide Induces Senescence and Repression of DNA Repair Pathways in Glioblastoma Cells via Activation of ATR–CHK1, p21, and NF-κB
Authors: Aasland Dorthe , Götzinger Laura , Hauck Laura , Berte Nancy , Meyer Jessica , Effenberger Melanie , Schneider Simon , Reuber Emelie E. , Roos Wynand P. , Tomicic Maja T. , Kaina Bernd , Christmann Markus
Published: March 2023

Expression and phosphorylation of E2F1 and DP1
Figure S6 from Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E
Authors: Zhang Ying , Pusch Stefan , Innes James , Sidlauskas Kastytis , Ellis Matthew , Lau Joanne , El-Hassan Tedani , Aley Natasha , Launchbury Francesca , Richard-Loendt Angela , deBoer Jasper , Chen Sheng , Wang Lei , von Deimling Andreas , Li Ningning , Brandner Sebastian
Published: March 2023

miR183 and SEMA3E expression in vitro
Figure S5 from Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E
Authors: Zhang Ying , Pusch Stefan , Innes James , Sidlauskas Kastytis , Ellis Matthew , Lau Joanne , El-Hassan Tedani , Aley Natasha , Launchbury Francesca , Richard-Loendt Angela , deBoer Jasper , Chen Sheng , Wang Lei , von Deimling Andreas , Li Ningning , Brandner Sebastian
Published: March 2023

Apoptotic response to ER stress in vitro and in vivo
Supplementary Figures S1- S22. from Role of Chromatin Damage and Chromatin Trapping of FACT in Mediating the Anticancer Cytotoxicity of DNA-Binding Small-Molecule Drugs
Authors: Nesher Elimelech , Safina Alfiya , Aljahdali Ieman , Portwood Scott , Wang Eunice S. , Koman Igor , Wang Jianmin , Gurova Katerina V.
Published: March 2023

Supplementary Figures S1-S4- Cytotoxicity data for four cell lines with all compounds used in the study. S5-S7 - C-trapping via western blotting with in three cell lines. S8-S9 - C-trapping via imaging on populations of cells with high and low magnifications. S10- Time dependence of c-trapping S11 - Comparison of drug accumulations in the nuclei of cells via autofluorescence. S12 - Effect of inhibition of MDR on cytotoxicity of the drugs. S13 - Comparison of the potency of c-trapping caused by different compounds in HCT116 cells S14. Quantitation of Histone H4 eviction. S15. Immunofluorescent staining of histone H3. S16. Comparison of patterns of c-trapping caused by high concentrations of the drugs. S17-S20 - Analyses of genome-wide distribution of FACT via ChIP-seq. S21. Assessment of DNA damaging properties of the compounds. S22. Assessment of correlations between different parameters measured. S
Figure S3 from Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E
Authors: Zhang Ying , Pusch Stefan , Innes James , Sidlauskas Kastytis , Ellis Matthew , Lau Joanne , El-Hassan Tedani , Aley Natasha , Launchbury Francesca , Richard-Loendt Angela , deBoer Jasper , Chen Sheng , Wang Lei , von Deimling Andreas , Li Ningning , Brandner Sebastian
Published: March 2023

Generation of IDH mutant brain tumours with tamoxifen induced Cre mediated recombination
Supplementary Table 1a from miR-450a Acts as a Tumor Suppressor in Ovarian Cancer by Regulating Energy Metabolism
Authors: Muys Bruna Rodrigues , Sousa Josane F. , Plaça Jessica Rodrigues , de Araújo Luíza Ferreira , Sarshad Aishe A. , Anastasakis Dimitrios G. , Wang Xiantao , Li Xiao Ling , de Molfetta Greice Andreotti , Ramão Anelisa , Lal Ashish , Vidal Daniel Onofre , Hafner Markus , Silva Wilson A.
Published: March 2023

Supplementary Table 1a. List of potential total miRNA and miR-450a only binding sites from A2780 control cell line
Supplementary Tables S9-12 from tRNA Fragments Show Intertwining with mRNAs of Specific Repeat Content and Have Links to Disparities
Authors: Telonis Aristeidis G. , Loher Phillipe , Magee Rogan , Pliatsika Venetia , Londin Eric , Kirino Yohei , Rigoutsos Isidore
Published: March 2023

This file contains the results on repeat element analyses and on the sex dependencies of tRF-mRNA correlations.
Supplementary Figure 3 from miR-450a Acts as a Tumor Suppressor in Ovarian Cancer by Regulating Energy Metabolism
Authors: Muys Bruna Rodrigues , Sousa Josane F. , Plaça Jessica Rodrigues , de Araújo Luíza Ferreira , Sarshad Aishe A. , Anastasakis Dimitrios G. , Wang Xiantao , Li Xiao Ling , de Molfetta Greice Andreotti , Ramão Anelisa , Lal Ashish , Vidal Daniel Onofre , Hafner Markus , Silva Wilson A.
Published: March 2023

Supplementary Figure 3. Protein blot from AGO proteins from nuclear and cytoplasmic portions of A2780.
Supplementary Table S6 from tRNA Fragments Show Intertwining with mRNAs of Specific Repeat Content and Have Links to Disparities
Authors: Telonis Aristeidis G. , Loher Phillipe , Magee Rogan , Pliatsika Venetia , Londin Eric , Kirino Yohei , Rigoutsos Isidore
Published: March 2023

This file contains the statistics of the length distribution of exons and introns of the genes that are correlated with nuclear and mitochondrial tRFs.
Supplementary Table S3 from Psychologic Distress Is Associated with Cancer-Specific Mortality among Patients with Cervical Cancer
Authors: Lu Donghao , Andrae Bengt , Valdimarsdóttir Unnur , Sundström Karin , Fall Katja , Sparén Pär , Fang Fang
Published: March 2023

Associations of subtypes of loss and severe illness of a family member with the risk of overall mortality.
Supplementary table 2 from SF3B2-Mediated RNA Splicing Drives Human Prostate Cancer Progression
Authors: Kawamura Norihiko , Nimura Keisuke , Saga Kotaro , Ishibashi Airi , Kitamura Koji , Nagano Hiromichi , Yoshikawa Yusuke , Ishida Kyoso , Nonomura Norio , Arisawa Mitsuhiro , Luo Jun , Kaneda Yasufumi
Published: March 2023

A list of antibodies used in the study
Supplementary Data from SF3B2-Mediated RNA Splicing Drives Human Prostate Cancer Progression
Authors: Kawamura Norihiko , Nimura Keisuke , Saga Kotaro , Ishibashi Airi , Kitamura Koji , Nagano Hiromichi , Yoshikawa Yusuke , Ishida Kyoso , Nonomura Norio , Arisawa Mitsuhiro , Luo Jun , Kaneda Yasufumi
Published: March 2023

This text file includes SF3B2 binding sites.
Supplemental Materials & Methods from Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models
Authors: Kukuyan Anna-Mariya , Sementino Eleonora , Kadariya Yuwaraj , Menges Craig W. , Cheung Mitchell , Tan Yinfei , Cai Kathy Q. , Slifker Michael J. , Peri Suraj , Klein-Szanto Andres J. , Rauscher Frank J. , Testa Joseph R.
Published: March 2023

Analysis of The Cancer Genome Atlas (TCGA) mesothelioma cases.
Supplementary Figure S3 from Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer
Authors: Combès Eve , Andrade Augusto F. , Tosi Diego , Michaud Henri-Alexandre , Coquel Flavie , Garambois Veronique , Desigaud Delphine , Jarlier Marta , Coquelle Arnaud , Pasero Philippe , Bonnefoy Nathalie , Moreaux Jerome , Martineau Pierre , Del Rio Maguy , Beijersbergen Roderick L. , Vezzio-Vie Nadia , Gongora Celine
Published: March 2023

Oxaliplatin combined with the ATR inhibitor VE-822 induces immune death signalling
Supplementary Figure 2 from Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer
Authors: Combès Eve , Andrade Augusto F. , Tosi Diego , Michaud Henri-Alexandre , Coquel Flavie , Garambois Veronique , Desigaud Delphine , Jarlier Marta , Coquelle Arnaud , Pasero Philippe , Bonnefoy Nathalie , Moreaux Jerome , Martineau Pierre , Del Rio Maguy , Beijersbergen Roderick L. , Vezzio-Vie Nadia , Gongora Celine
Published: March 2023

Effect of ATR inhibition combined with oxaliplatin treatment on the ATR and ATM pathways.
Supplementary Data from Histone Demethylase KDM4B Promotes DNA Damage by Activating Long Interspersed Nuclear Element-1
Authors: Xiang Ying , Yan Kai , Zheng Qian , Ke Haiqiang , Cheng Jie , Xiong Wenjun , Shi Xin , Wei Lei , Zhao Min , Yang Fei , Wang Ping , Lu Xing , Fu Li , Lu Xuemei , Li Feng
Published: March 2023

Supplementary Tables - Supplementary Tables S1-3. Table S1. List of quantitative RT-PCR primers used in this study; Table S2. List of ChIP-qPCR primers used in this study; Supplementary Table S3. Distribution of H3K9me3 ChIP-seq peaks in various types of human cancer cells. Supplementary Figures - Supplementary Figures S1-7. Supplementary Figure S1. Enrichment profile plots of the KDM4B-dependent H3K9me3 peaks overlapped SINE, LTR, genebody and intergenic in three cell types; Supplementary Figure S2. The LINE-1 phylogenetic tree and the evaluation of H3K9me3 signal in selected evolutionarily young LINE-1 element; Supplementary Figure S3. Effect of KDM4 proteins on LINE-1 expression; Supplementary Figure S4. Schematic illustration of retrotransposition cassette assay; Supplementary Figure S5. The ORF1p, global H3K9me3 and DNA damage level were detected in various breast cell lines; Supplementary Figure S6. The retrotransposition cassette assay in breast cancer cells and normal breast epithelial cells; Supplementary Figure S7. ORF2 expression is sufficient to induce the DNA damage.
Supplementary Data from Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration
Authors: Singh Manjulata , Tian Xiao-Jun , Donnenberg Vera S. , Watson Alan M. , Zhang JingYu , Stabile Laura P. , Watkins Simon C. , Xing Jianhua , Sant Shilpa
Published: March 2023

Supplementary video showing migration of a microtumor
Supplementary Data from Imaging of Activated T Cells as an Early Predictor of Immune Response to Anti-PD-1 Therapy
Authors: Levi Jelena , Lam Tina , Goth Samuel R. , Yaghoubi Shahriar , Bates Jennifer , Ren Gang , Jivan Salma , Huynh Tony L. , Blecha Joseph E. , Khattri Roli , Schmidt Karl F. , Jennings Dominique , VanBrocklin Henry
Published: March 2023

FACS analyses, expression of transporters and kinases in immune cells, tumor growth.
Supplementary Figures 1-8 from M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer
Authors: Lan Jingqin , Sun Li , Xu Feng , Liu Lu , Hu Fuqing , Song Da , Hou Zhenlin , Wu Wei , Luo Xuelai , Wang Jing , Yuan Xianglin , Hu Junbo , Wang Guihua
Published: March 2023

Supplementary Figures 1-8ï¼š Supplementary Figure 1 Exosomes were produced by M2 macrophage. Supplementary Figure 2 M2-macrophage-derived exosomes enhance cell mobility, migration and invasion in SW480 and HCT 116 cells. Supplementary Figure 3 Increased miR-21-5p and miR-155-5p in exosomes and SW48 cells treated with exosomes derived from M2 macrophage. Supplementary Figure 4 BRG1 is the target of miR-21-5p and miR-155-5p Supplementary Figure 5 Downregulated BRG1 promote CRC cell migration and invasion. Supplementary Figure 6 BRG1 mediates CRC migration and invasion induced by M2 derived exosomes. Supplementary Figure 7 M2-macrophage-derived exosomes enhance cell migration and invasion in CO-115. Supplementary Figure 8 Quantification of relative protein level of BRG1 based on three independent tests for Fig. 6B.
Supplementary Data from Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma
Authors: Feddersen Charlotte R. , Schillo Jacob L. , Varzavand Afshin , Vaughn Hayley R. , Wadsworth Lexy S. , Voigt Andrew P. , Zhu Eliot Y. , Jennings Brooke M. , Mullen Sarah A. , Bobera Jeremy , Riordan Jesse D. , Stipp Christopher S. , Dupuy Adam J.
Published: March 2023

Supplemental figures showing more detailed analysis of the genetic screen results (S1-S3), additional experiments showing biological validation of major candidate genes (S4-S7), and characterization of spontaneous Vemurafenib resistance in A375 cells (S8).
Table S2 from APC/C-CDH1–Regulated IDH3β Coordinates with the Cell Cycle to Promote Cell Proliferation
Authors: Wu Qingnan , Zhang Weimin , Xue Liyan , Wang Yan , Fu Ming , Ma Liying , Song Yongmei , Zhan Qi-Min
Published: March 2023

Supplementary Table S2 Metabolic gene with CNV larger than 20%.
Supplementary Video 1 from A Direct Podocalyxin–Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells
Authors: Wong Bin Sheng , Shea Daniel J. , Mistriotis Panagiotis , Tuntithavornwat Soontorn , Law Robert A. , Bieber Jake M. , Zheng Lei , Konstantopoulos Konstantinos
Published: March 2023

PODXL knockdown impairs 2D random migration of metastatic pancreatic cancer cells. Representative scramble control (left) and PODXL-KD (right) SW1990 cells migrating on collagen I-coated glass coverslips. Scale bar represents 50 µm. Related to Fig. 1B.
Table S1 from Glutamate Decarboxylase 65 Signals through the Androgen Receptor to Promote Castration Resistance in Prostate Cancer
Authors: Gao Yi , Chen Lu , Du ZunGuo , Gao WenChao , Wu ZhengMing , Liu XiuJuan , Huang Hai , Xu DanFeng , Li QingQuan
Published: March 2023

Table S1 shows the detailed information of PDX lines used in this study
Figure S5 from Glutamate Decarboxylase 65 Signals through the Androgen Receptor to Promote Castration Resistance in Prostate Cancer
Authors: Gao Yi , Chen Lu , Du ZunGuo , Gao WenChao , Wu ZhengMing , Liu XiuJuan , Huang Hai , Xu DanFeng , Li QingQuan
Published: March 2023

Figure S5 shows the effects of GAD65 knockdown on CRPC growth and progression
Supplementary Tables S1-3 from TLR Signaling Is Activated in Lymph Node–Resident CLL Cells and Is Only Partially Inhibited by Ibrutinib
Authors: Dadashian Eman L. , McAuley Erin M. , Liu Delong , Shaffer Arthur L. , Young Ryan M. , Iyer Jessica R. , Kruhlak Michael J. , Staudt Louis M. , Wiestner Adrian , Herman Sarah E. M.
Published: March 2023

Supplementary Table S1: Patient Characteristics Supplementary Table S2: Experimentally derived gene sets and reference list Supplementary Table S3: TLR signature differentially expressed gene list
Supplementary Figures S1-S9 from CXADR-Mediated Formation of an AKT Inhibitory Signalosome at Tight Junctions Controls Epithelial–Mesenchymal Plasticity in Breast Cancer
Authors: Nilchian Azadeh , Johansson Joel , Ghalali Aram , Asanin Sandra T. , Santiago Ana , Rosencrantz Oskar , Sollerbrant Kerstin , Vincent C. Theresa , Sund Malin , Stenius Ulla , Fuxe Jonas
Published: March 2023

This file includes supplementary figures S1-S9: Figure S1. Immunofluorescence and western blot results showing differences in CXADR expression between EpH4, EpRas and EpXT cells. Figure S2. Western blots showing how incubatino with an AKT inhibitor, or knockdown of CXADR affects EMT markers in EpRas cells. Figure S3. Immunofluorescence images showing co-localization of CXADR with PHLPP2, PTEN and MAGI-1 in EpH4 cells. Figure S4. Results from Co-IP experiments, protein stability assays, and confuency experiments. Figure S5. Immunofluorescence staining of PHLPP2 and PTEN in the intestinal epithelium of CXADR-deficient mice. Figure S6. Kaplan-Meier curves showing how the expression of CXADR and other junction proteins correlates with overall survival in the GOBO database. Figure S7. Kaplan-Meier curves showing how the expression of MAGI1, PTEN and PHLPP2 correlates with overall survival in the GOBO database. Figure S8. Schematic diagram showing the expression of CXADR in 51 human breast cancer cells. Immunofluorescence and western blot results showing how overexpression of CXADR affects EMT markers and signalosome components in breast and lung cancer cells. Figure S9. Scatter plots showing variability in staining of MAGI-1, PTEN, PHLPP2 and E-cadherin in luminal A and basal tumors.
Table S1 from LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in KRAS-Mutant Lung Adenocarcinoma
Authors: Galan-Cobo Ana , Sitthideatphaiboon Piyada , Qu Xiao , Poteete Alissa , Pisegna Marlese A. , Tong Pan , Chen Pei-Hsuan , Boroughs Lindsey K. , Rodriguez Mirna L.M. , Zhang Winter , Parlati Francesco , Wang Jing , Gandhi Varsha , Skoulidis Ferdinandos , DeBerardinis Ralph J. , Minna John D. , Heymach John V.
Published: March 2023

Abbreviations used in the manuscript.
Supplementary Tables from Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress
Authors: Young Lucy A. , O'Connor Lenka Oplustil , de Renty Christelle , Veldman-Jones Margaret H. , Dorval Thierry , Wilson Zena , Jones David R. , Lawson Deborah , Odedra Rajesh , Maya-Mendoza Apolinar , Reimer Corinne , Bartek Jiri , Lau Alan , O'Connor Mark J.
Published: March 2023

This file contains Supplementary Tables 1-6. Table S1 lists the growth inhibitory values of AZD6738 and cell doubling rates in DLBCL cell lines used in the study. Table S2 details the median replication fork velocities of DLBCL cell lines treated with DMSO and AZD6738 in Figure 3. Table S3 lists the statistical significance for DNA fibre analysis in Figure 3. Tables S4-S6 summarise the in vivo experiment groups used in the manuscript, including animal numbers in study, efficacy and body weight loss.
Table S2 from Glucocorticoid Receptor Signaling Activates TEAD4 to Promote Breast Cancer Progression
Authors: He Lingli , Yuan Liang , Sun Yang , Wang Pingyang , Zhang Hailin , Feng Xue , Wang Zuoyun , Zhang Wenxiang , Yang Chuanyu , Zeng Yi Arial , Zhao Yun , Chen Ceshi , Zhang Lei
Published: March 2023

Expression of TEAD4 and GR in breast cancer samples
Supplementary Data from A Multigene Assay Determines Risk of Recurrence in Patients with Triple-Negative Breast Cancer
Authors: Stewart Rachel L. , Updike Katherine L. , Factor Rachel E. , Henry N. Lynn , Boucher Kenneth M. , Bernard Philip S. , Varley Katherine E.
Published: March 2023

Supplemental Figures 1-7 include a graphical outline of the study, graphs depicting probe performance, correlations between MHCII and TIL scores, ROC statistics, and additional Kaplan Meier curves.
Figure S6 from Glucocorticoid Receptor Signaling Activates TEAD4 to Promote Breast Cancer Progression
Authors: He Lingli , Yuan Liang , Sun Yang , Wang Pingyang , Zhang Hailin , Feng Xue , Wang Zuoyun , Zhang Wenxiang , Yang Chuanyu , Zeng Yi Arial , Zhao Yun , Chen Ceshi , Zhang Lei
Published: March 2023

Supplementary Figure 6. Glucocorticoids promote breast cancer cell survival and migration dependent on both TEAD4 and GR.
Figure S2 from Glucocorticoid Receptor Signaling Activates TEAD4 to Promote Breast Cancer Progression
Authors: He Lingli , Yuan Liang , Sun Yang , Wang Pingyang , Zhang Hailin , Feng Xue , Wang Zuoyun , Zhang Wenxiang , Yang Chuanyu , Zeng Yi Arial , Zhao Yun , Chen Ceshi , Zhang Lei
Published: March 2023

Supplementary Figure 2. Glucocorticoids promote TEAD4 nuclear accumulation.
Figure S1 from Glucocorticoid Receptor Signaling Activates TEAD4 to Promote Breast Cancer Progression
Authors: He Lingli , Yuan Liang , Sun Yang , Wang Pingyang , Zhang Hailin , Feng Xue , Wang Zuoyun , Zhang Wenxiang , Yang Chuanyu , Zeng Yi Arial , Zhao Yun , Chen Ceshi , Zhang Lei
Published: March 2023

Supplementary Figure 1. Glucocorticoids up-regulate TEAD4.
Figure S3 from Upregulation of PD-L1 via HMGB1-Activated IRF3 and NF-κB Contributes to UV Radiation-Induced Immune Suppression
Authors: Wang Wei , Chapman Nicole M. , Zhang Bo , Li Mingqi , Fan Meiyun , Laribee R. Nicholas , Zaidi M. Raza , Pfeffer Lawrence M. , Chi Hongbo , Wu Zhao-Hui
Published: March 2023

SIRT1 inactivation upon UVR promotes HMGB1 acetylation and secretion.
Figure S2 from Upregulation of PD-L1 via HMGB1-Activated IRF3 and NF-κB Contributes to UV Radiation-Induced Immune Suppression
Authors: Wang Wei , Chapman Nicole M. , Zhang Bo , Li Mingqi , Fan Meiyun , Laribee R. Nicholas , Zaidi M. Raza , Pfeffer Lawrence M. , Chi Hongbo , Wu Zhao-Hui
Published: March 2023

UVB-induced NF-kB activation is independent of p38, CK2, TAK1 and DDR kinases.
Figure S1 from Upregulation of PD-L1 via HMGB1-Activated IRF3 and NF-κB Contributes to UV Radiation-Induced Immune Suppression
Authors: Wang Wei , Chapman Nicole M. , Zhang Bo , Li Mingqi , Fan Meiyun , Laribee R. Nicholas , Zaidi M. Raza , Pfeffer Lawrence M. , Chi Hongbo , Wu Zhao-Hui
Published: March 2023

PD-L1 is upregulated in skin cells which correlates to NF-kB activation.
Key resources table from Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling
Authors: D'Agostino Luca , Nie Yingchao , Goswami Sayantani , Tong Kevin , Yu Shiyan , Bandyopadhyay Sheila , Flores Juan , Zhang Xiao , Balasubramanian Iyshwarya , Joseph Ivor , Sakamori Ryotaro , Farrell Victoria , Li Qi , Yang Chung S. , Gao Bin , Ferraris Ronaldo P. , Yehia Ghassan , Bonder Edward M. , Goldenring James R. , Verzi Michael P. , Zhang Lanjing , Ip Y. Tony , Gao Nan
Published: March 2023

Contains the names and the sources of the various antibodies and reagents utilized. Additionally, it also contains the oligonucleotide primers designed for quantitative PCR analysis.
Figure S7 from Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo
Authors: Xue Yuezhen , Barker Nick , Hoon Shawn , He Pingping , Thakur Teena , Abdeen Shifana Raja , Maruthappan Priadarsini , Ghadessy Farid J. , Lane David P.
Published: March 2023

Upregulation of p53 target genes in response to bortezomib in HCT116 p53+/+ xenograft tumors.
Supplementary Figure 3 from Activation of Peroxisome Proliferator-Activated Receptors α and δ Synergizes with Inflammatory Signals to Enhance Adoptive Cell Therapy
Authors: Saibil Samuel D. , St. Paul Michael , Laister Robert C. , Garcia-Batres Carlos R. , Israni-Winger Kavita , Elford Alisha R. , Grimshaw Natasha , Robert-Tissot Céline , Roy Dominic G. , Jones Russell G. , Nguyen Linh T. , Ohashi Pamela S.
Published: March 2023

Shows increased IFNgamma mRNA and T-bet expression in GW treated cells
Supplementary Figure S5 from Chromosome 12p Amplification in Triple-Negative/BRCA1-Mutated Breast Cancer Associates with Emergence of Docetaxel Resistance and Carboplatin Sensitivity
Authors: Gómez-Miragaya Jorge , Díaz-Navarro Ander , Tonda Raul , Beltran Sergi , Palomero Luis , Palafox Marta , Dobrolecki Lacey E. , Huang Chen , Vasaikar Suhas , Zhang Bing , Wulf Gerburg M. , Collado-Sole Alejandro , Trinidad Eva M. , Muñoz Purificación , Paré Laia , Prat Aleix , Bruna Alejandra , Caldas Carlos , Arribas Joaquín , Soler-Monso María Teresa , Petit Anna , Balmaña Judith , Cruz Cristina , Serra Violeta , Pujana Miguel Angel , Lewis Michael T. , Puente Xose S. , González-Suárez Eva
Published: March 2023

Chr12p amplification predicts better response to carboplatin
Supplementary Figure S3 from Chromosome 12p Amplification in Triple-Negative/BRCA1-Mutated Breast Cancer Associates with Emergence of Docetaxel Resistance and Carboplatin Sensitivity
Authors: Gómez-Miragaya Jorge , Díaz-Navarro Ander , Tonda Raul , Beltran Sergi , Palomero Luis , Palafox Marta , Dobrolecki Lacey E. , Huang Chen , Vasaikar Suhas , Zhang Bing , Wulf Gerburg M. , Collado-Sole Alejandro , Trinidad Eva M. , Muñoz Purificación , Paré Laia , Prat Aleix , Bruna Alejandra , Caldas Carlos , Arribas Joaquín , Soler-Monso María Teresa , Petit Anna , Balmaña Judith , Cruz Cristina , Serra Violeta , Pujana Miguel Angel , Lewis Michael T. , Puente Xose S. , González-Suárez Eva
Published: March 2023

Supplementary Figure S3
Supplementary Table S2 from SRSF3-Regulated RNA Alternative Splicing Promotes Glioblastoma Tumorigenicity by Affecting Multiple Cellular Processes
Authors: Song Xiao , Wan Xuechao , Huang Tianzhi , Zeng Chang , Sastry Namratha , Wu Bingli , James C. David , Horbinski Craig , Nakano Ichiro , Zhang Wei , Hu Bo , Cheng Shi-Yuan
Published: March 2023

List of SRSF3-affected AS events in GSCs
Supplementary Methods from Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia
Authors: Hosseini Mohsen , Rezvani Hamid Reza , Aroua Nesrine , Bosc Claudie , Farge Thomas , Saland Estelle , Guyonnet-Dupérat Véronique , Zaghdoudi Sonia , Jarrou Latifa , Larrue Clément , Sabatier Marie , Mouchel Pierre Luc , Gotanègre Mathilde , Piechaczyk Marc , Bossis Guillaume , Récher Christian , Sarry Jean-Emmanuel
Published: March 2023

Supplementary Methods
Supplementary Tables from Landscape of Germline and Somatic Mitochondrial DNA Mutations in Pediatric Malignancies
Authors: Triska Petr , Kaneva Kristiyana , Merkurjev Daria , Sohail Noor , Falk Marni J. , Triche Timothy J. , Biegel Jaclyn A. , Gai Xiaowu
Published: March 2023

Supplementary Tables 1-18 shows 1) mtDNA mutations found in 616 pediatric cancer samples, 2) calculation of expected dN/dS ratio, 3) mtDNA mutations found in 2202 tumor samples studied by two previous studies, 4) the number of nuclear and mtDNA somatic mutations found in 134 randomly selected tumor samples, 5) mtDNA genome coverage for all tumor samples studies, 6) mtDNA genome coverage for all matched normal samples studies, 7) samples with low mtDNA coverage, 8) mtDNA genome coverage for non-cancer children, 9) mtDNA variants found in matched normal samples, 10) mtDNA variants found in non-cancer samples, 11) samples with known pathogenic mtDNA variants, 12) mitochondrial haplogroups for all patients studies, 13) number of cancer patients by mtDNA haplogroup, 14) number of patients of each haplogroup by cancer subtype, 15) permutation results from meta-analysis, 16) meta-analysis of long homopolymer regions, 17) meta-analysis results of mtDNA tRNA mutations, 18) mtDNA mutations found in 5 mtDNA hypermutated cancer samples.
Supplementary Figures 1-14 from Antitumor Effects of Anti-Semaphorin 4D Antibody Unravel a Novel Proinvasive Mechanism of Vascular-Targeting Agents
Authors: Zuazo-Gaztelu Iratxe , Pàez-Ribes Marta , Carrasco Patricia , Martín Laura , Soler Adriana , Martínez-Lozano Mar , Pons Roser , Llena Judith , Palomero Luis , Graupera Mariona , Casanovas Oriol
Published: March 2023

Supplementary figures on vessel phenotype, tumor effects, combo treatment, macrophage phenotype and effects, and human validation.
Supplementary Data Index from Antitumor Effects of Anti-Semaphorin 4D Antibody Unravel a Novel Proinvasive Mechanism of Vascular-Targeting Agents
Authors: Zuazo-Gaztelu Iratxe , Pàez-Ribes Marta , Carrasco Patricia , Martín Laura , Soler Adriana , Martínez-Lozano Mar , Pons Roser , Llena Judith , Palomero Luis , Graupera Mariona , Casanovas Oriol
Published: March 2023

Index of all Supplementary Data
Supplementary Figure 4 from Landscape of Germline and Somatic Mitochondrial DNA Mutations in Pediatric Malignancies
Authors: Triska Petr , Kaneva Kristiyana , Merkurjev Daria , Sohail Noor , Falk Marni J. , Triche Timothy J. , Biegel Jaclyn A. , Gai Xiaowu
Published: March 2023

Supplementary Figure 4 illustrates that mtDNA mutations of different mtDNA genes have varied predicted pathogenicity.
Supplementary Data from Upregulation of Myt1 Promotes Acquired Resistance of Cancer Cells to Wee1 Inhibition
Authors: Lewis Cody W. , Bukhari Amirali B. , Xiao Edric J. , Choi Won-Shik , Smith Joanne D. , Homola Ellen , Mackey John R. , Campbell Shelagh D. , Gamper Armin M. , Chan Gordon K.
Published: March 2023

suppl figures 1-6. SF1: Myt1 knockdown sensitizes breast cells to Adavosertib; SF2: Wee1 knockdown mimics Adavosertib treatment; SF3: Adavosertib does not inhibit Myt1 activity; SF4: Adavosertib resistant cells do not prematurely enter mitosis; SF5: Adavosertib induced mitotic exit delays occur in cells with and without abnormal chromosome condensation and spindle organization; SF6: Myt1 but not Wee1 is associated with a worse clinical outcome. Suppl. Table 1. p53 and molecular subtypes of breast cell lines. * indicate non-tumorigenic cell lines; Suppl Table 2. Cell line sensitive to Adavosertib in the presence of siSc or siMyt1; Suppl Table 3. Cdk1 inhibition prevents centromere fragmentation
Supplementary Figure S3 from A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3AR882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and Leukemogenesis
Authors: Lu Rui , Wang Jun , Ren Zhihong , Yin Jiekai , Wang Yinsheng , Cai Ling , Wang Gang Greg
Published: March 2023

This contains Supplementary Figure S3, which shows dose-dependent effect by DNMT3A hotspot mutation on transformation and CpG hypomethylation.
Supplementary Figure S2 from A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3AR882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and Leukemogenesis
Authors: Lu Rui , Wang Jun , Ren Zhihong , Yin Jiekai , Wang Yinsheng , Cai Ling , Wang Gang Greg
Published: March 2023

This contains Supplementary Figure S2, which reveals CpG hypomethylation included by DNMT3A hotspot mutations.
Supplementary Figures S1-S7 from ATMIN Is a Tumor Suppressor Gene in Lung Adenocarcinoma
Authors: Foster Hanna , Ruiz E. Josue , Moore Christopher , Stamp Gordon W. H. , Nye Emma L. , Li Ningning , Pan Yihang , He Yulong , Downward Julian , Behrens Axel
Published: March 2023

Supplementary figure S1. ATM is altered in LUAD and reduced expression correlates with poor survival. Supplementary figure S2. ATMIN and ATM immunohistochemical staining on LUAD and adjacent normal lung tissue. Supplementary figure S3. LUAD tumors deficient for Atmin or Atm exhibit activation of MAPK pathway and increase cell proliferation. Supplementary figure S4. Deletion of Atmin or Atm increases LUAD tumor burden. Supplementary figure S5. AtminÎ"L/+ KP tumor cells-maintained expression of Atmin target gene Dynll1. Supplementary figure S6. Homozygous and Heterozygous Atmin loss increases cell proliferation and tumor grafts. Supplementary figure S7. ATM and ATMIN deficiency confers resistance to replication stress.
Supplementary Data from Dysfunction of Poly (ADP-Ribose) Glycohydrolase Induces a Synthetic Lethal Effect in Dual Specificity Phosphatase 22-Deficient Lung Cancer Cells
Authors: Sasaki Yuka , Fujimori Hiroaki , Hozumi Miyuki , Onodera Takae , Nozaki Tadashige , Murakami Yasufumi , Ashizawa Kazuto , Inoue Kengo , Koizumi Fumiaki , Masutani Mitsuko
Published: March 2023

Figure S3 shows PAR accumulation in PARG knocked down A549 cells.
Supplementary Data from Dysfunction of Poly (ADP-Ribose) Glycohydrolase Induces a Synthetic Lethal Effect in Dual Specificity Phosphatase 22-Deficient Lung Cancer Cells
Authors: Sasaki Yuka , Fujimori Hiroaki , Hozumi Miyuki , Onodera Takae , Nozaki Tadashige , Murakami Yasufumi , Ashizawa Kazuto , Inoue Kengo , Koizumi Fumiaki , Masutani Mitsuko
Published: March 2023

TableS1 shows primer sequences for qRT-PCR.
Table S1 from SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program
Authors: Oliphant Michael U.J. , Vincent Melanie Y. , Galbraith Matthew D. , Pandey Ahwan , Zaberezhnyy Vadym , Rudra Pratyaydipta , Johnson Katherine R. , Costello James C. , Ghosh Debashis , DeGregori James , Espinosa Joaquin M. , Ford Heide L.
Published: March 2023

List of Oligos and Antibodies
Supplementary Materials and Methods from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
Authors: Tomé Mercedes , Pappalardo Angela , Soulet Fabienne , López José Javier , Olaizola Jone , Leger Yannick , Dubreuil Marielle , Mouchard Amandine , Fessart Delphine , Delom Frédéric , Pitard Vincent , Bechade Dominique , Fonck Mariane , Rosado Juan Antonio , Ghiringhelli François , Déchanet-Merville Julie , Soubeyran Isabelle , Siegfried Geraldine , Evrard Serge , Khatib Abdel-Majid
Published: March 2023

Detailed description of the methodology performed.
Supplementary Figures with Figure legends. from CDK4 Regulates Lysosomal Function and mTORC1 Activation to Promote Cancer Cell Survival
Authors: Martínez-Carreres Laia , Puyal Julien , Leal-Esteban Lucía C. , Orpinell Meritxell , Castillo-Armengol Judit , Giralt Albert , Dergai Oleksandr , Moret Catherine , Barquissau Valentin , Nasrallah Anita , Pabois Angélique , Zhang Lianjun , Romero Pedro , Lopez-Mejia Isabel C. , Fajas Lluis
Published: March 2023

Supplementary Figures and Supplementary Figure legends. Supplementary Fig. 1.- CDK4 inhibition or depletion decreases mTORC1 activity in several cancer cell lines, Supplementary Fig. 2.- CDK4 effects on mTORC1 are α-ketoglutarate and E2F1-independent, Supplementary Fig. 3.- CDK4 phosphorylates FLCN, Supplementary Fig. 4.- CDK4 regulates mTORC1 activity through phosphorylating FLCN, Supplementary Fig. 5.- CDK4 inhibition or depletion increases lysosomal mass, Supplementary Fig. 6.- Hematoxylin and eosin staining and gene expression analysis of tumors from mice treated with or without LY2835219, Supplementary Fig. 7.- In vitro cell death analysis and in vivo electron microscopy analysis of tumors treated with DMSO, LY2835219, A769662 and the combination of A769662 with LY2835219
Video S1 from A Microbial Siderophore-Inspired Self-Gelling Hydrogel for Noninvasive Anticancer Phototherapy
Authors: Ko Seungbeom , Park Joo Yeon , Oh Yu-Kyoung
Published: March 2023

Self-gelling of HA-GA/Fe hydrogel
Figure S5 from A Microbial Siderophore-Inspired Self-Gelling Hydrogel for Noninvasive Anticancer Phototherapy
Authors: Ko Seungbeom , Park Joo Yeon , Oh Yu-Kyoung
Published: March 2023

Blood-time profile of hydrogel
Figure S2 from Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance
Authors: Ly Michelle , Rentas Stefan , Vujovic Ana , Wong Nicholas , Moreira Steven , Xu Joshua , Holzapfel Nicholas , Bhatia Sonam , Tran Damian , Minden Mark D. , Draper Jonathan S. , Hope Kristin J.
Published: March 2023

This figure shows the down regulation of AHR targets in specific subtypes of AML and the genes driving negative enrichment of AHR down regulated targets in LSCs
Figure S1 from Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance
Authors: Ly Michelle , Rentas Stefan , Vujovic Ana , Wong Nicholas , Moreira Steven , Xu Joshua , Holzapfel Nicholas , Bhatia Sonam , Tran Damian , Minden Mark D. , Draper Jonathan S. , Hope Kristin J.
Published: March 2023

This figure displays the elevated expression of MSI2 in LSCs and depicts the reduced leukemic burden in xenografts upon MSI2 knockdown
Video 5 from MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1
Authors: Chuang Huai-Chia , Chang Chih-Chi , Teng Chiao-Fang , Hsueh Chia-Hsin , Chiu Li-Li , Hsu Pu-Ming , Lee Ming-Ching , Hsu Chung-Ping , Chen Yi-Rong , Liu Yi-Chung , Lyu Ping-Chiang , Tan Tse-Hua
Published: March 2023

Video 5.avi GLK co-localizes with IQGAP1 at the leading edge of a migrating cell (Cell #5).
Supplementary Figs S9-11 from ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer
Authors: Vartanian Steffan , Lee James , Klijn Christiaan , Gnad Florian , Bagniewska Maria , Schaefer Gabriele , Zhang Donglu , Tan Jenille , Watson Sara A. , Liu Liling , Chen Honglin , Liang Yuxin , Watanabe Colin , Cuellar Trinna , Kan David , Hartmaier Ryan J. , Lau Ted , Costa Michael R. , Martin Scott E. , Merchant Mark , Haley Benjamin , Stokoe David
Published: March 2023

Figures S9-11. Effects of knocking down genes involved in oxidative stress
Supplementary Fig S15 from ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer
Authors: Vartanian Steffan , Lee James , Klijn Christiaan , Gnad Florian , Bagniewska Maria , Schaefer Gabriele , Zhang Donglu , Tan Jenille , Watson Sara A. , Liu Liling , Chen Honglin , Liang Yuxin , Watanabe Colin , Cuellar Trinna , Kan David , Hartmaier Ryan J. , Lau Ted , Costa Michael R. , Martin Scott E. , Merchant Mark , Haley Benjamin , Stokoe David
Published: March 2023

Figure S15. Relationship between KEAP1 mutant status and other genes in NSCLC
Supplementary Data from A Large-Cohort, Longitudinal Study Determines Precancer Disease Routes across Different Cancer Types
Authors: Hu Jessica X. , Helleberg Marie , Jensen Anders B. , Brunak Søren , Lundgren Jens
Published: March 2023

Figure S1 Figure S2 Figure S3 Figure S4 Figure S5
Legends Supplementary Data from T-Type Cav3.1 Channels Mediate Progression and Chemotherapeutic Resistance in Glioblastoma
Authors: Visa Anna , Sallán Marta C. , Maiques Oscar , Alza Lía , Talavera Elisabet , López-Ortega Ricard , Santacana Maria , Herreros Judit , Cantí Carles
Published: March 2023

Legends to Supplementary Figures
Figure S4 from T-Type Cav3.1 Channels Mediate Progression and Chemotherapeutic Resistance in Glioblastoma
Authors: Visa Anna , Sallán Marta C. , Maiques Oscar , Alza Lía , Talavera Elisabet , López-Ortega Ricard , Santacana Maria , Herreros Judit , Cantí Carles
Published: March 2023

Characterization of TMZ-resistant cell lines.
Supplementary Table S1 from Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response
Authors: Ramamoorthy Prabhu , Thomas Sufi Mary , Kaushik Gaurav , Subramaniam Dharmalingam , Chastain Katherine M. , Dhar Animesh , Tawfik Ossama , Kasi Anup , Sun Weijing , Ramalingam Satish , Gunewardena Sumedha , Umar Shahid , Mammen Joshua M. , Padhye Subhash B. , Weir Scott J. , Jensen Roy A. , Sittampalam G. Sitta , Anant Shrikant
Published: March 2023

Patient characteristics of primary tumor derived cultures.
Supplementary Table S1 from Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors
Authors: Barazas Marco , Gasparini Alessia , Huang Yike , Küçükosmanoğlu Asli , Annunziato Stefano , Bouwman Peter , Sol Wendy , Kersbergen Ariena , Proost Natalie , de Korte-Grimmerink Renske , van de Ven Marieke , Jonkers Jos , Borst Gerben R. , Rottenberg Sven
Published: March 2023

IHC scoring for 53BP1-positive cells. Related to Fig. 4D.