bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical effectiveness and prospects of methylene blue: A systematic review
Authors: Seitkazina Assel , Yang Jin-Kyoung , Kim Sehoon
Published: September 2022

Methylene blue (MB) is a well-known pharmaceutical ingredient that is thought to have a multi-targeted therapeutic effect as an anti-malarial and neuroprotective agent and has recently been identified as a treatment for coronavirus disease 2019 (COVID-19). In this review, we present an overview of relevant clinical trials, including ongoing trials, on the therapeutic uses of MB. A search for clinical trials on clinicaltrials.gov was performed using the terms “methylene blue” and “methylthionine chloride.” This review focuses on clinical trials of MB-based therapies applied to brain diseases, cancer imaging and diagnosis, infectious diseases such as malaria or COVID-19, and cardiovascular diseases. Nanoparticle-based delivery techniques have also been briefly discussed in addition to common delivery methods.
Suicidal ideation and long work hours by gender in Korean employees: The Kangbuk Samsung Workplace Mental Health Study: A cross-sectional study
Authors: Lee Heejun , Cho Sung Joon , Shin Young-Chul , Shin Dong-Won , Park Jae-Hyun , Kim Mukyeong , Oh Kang-Seob , Jeon Sang-Won
Published: September 2022

Purpose: This study investigated the relationship between increased working hours and suicidal ideation among Korean full-time employees by gender.Methods: Participants were employees from 54 companies and local government organizations in Korea, aged 19 to 68, who completed a self-reported questionnaire on sociodemographic factors, daily perceived stress, resilience, depressive symptoms, and suicidal ideation. Of the initial 15,360 respondents, participants who worked less than 40 hours were excluded. The final sample size was 9,326 (5,652 men, 3,674 women). Sociodemographic factors and psychological characteristics of participants with suicidal ideation were analyzed using Student’s t-tests and chi-square tests for continuous and categorical variables, respectively. Hierarchical logistic regression analyses were performed using suicidality as the dependent variable respectively for all participants, for male, and female. Furthermore, we used these results to compare differences between men and women associated with regard to long working hours to better understand how long working hours correlate with suicidal ideation; further, we examined the impact of gender on this relationship.Results: In univariate analyses, suicidal ideation was associated with increased working hours. Hierarchical logistic regression analyses of sociodemographic and psychological factors found no association between long working hours and suicidal ideation for the participants overall. However, they showed significant differences between men and women, such that long working hours were associated with suicidal ideation in men but were non-significant for women.Conclusion: Suicidal ideation is associated with long working hours among Korean male full-time workers, while other factors are more likely to lead to suicidal ideation among female workers. Suicide prevention measures for employees should thus be developed based on gender.
The role of the researcher in participatory processes: A study of learning about place and place attachment in communities
Authors: Elmersjö Magdalena , Bertilsdotter Rosqvist Hanna
Published: September 2022

This article explores what the present researchers have learned about place and place attachment in connection with an ongoing study of homemaking, belonging, and the significance of place for older people. The article is a contribution to research on the role of the researcher in the field, with a particular focus on the researcher’s own place attachment in the research process. The data comprises interviews, observations and diaries, and the writing of it was an iterative process that took place within a place attachment process. We are interested in the impact of place on what researchers learn about place and their own place attachment process - in relation to the idea of a place and its inhabitants as co-producers of each other. To be place attached means having an identity that is connected to a place, and it has been suggested that this has an impact on community development and social community capacity. The articleprovides insights into the place attachment of the researchers, and how the value of time spent at a place is central to embracing place and becoming fully part of the participatory process, bringing truthfulness to participatory community-based research.
Ethnopharmacological Review of Terminalia chebula
Authors: R Chandrasekar
Published: September 2022

Terminalia chebula, traditionally regarded as universal panacea, is known for its pleiotropic effects, including the effects on oxidative stress, malignant tumor growth, wound healing, and insulin sensitivity in Type 2 diabetes. In India and Southeast Asia the fruit is used as a popular folk medicine for antitussive, diuretic, homeostatic, laxative and cardiotonic treatments. In the fruits of T. chebula three hydrolyzable tannins chebulinic acid, chebulagic acid and 1, 3, 6-tri-O-galloylß-D-glucose could be determined by RP-HPLC. The contents of the first two substances were interrelated with the varieties. Experimental studies presented by different article show important action of substance present in fruit pulp Terminalia chebula, Antibacterial activity Test showed a broad spectrum of antibacterial activity with an inhibition zone size of 11 to 27 mm, against all the test bacteria. There was a synergistic action of the crude extracts with broad spectrum antibiotic like tetracycline and other pulp extract also act on viral disease In vitro they may inhibited the replication of human cytomegalovirus growth. Antioxidant activity of T. chebula fruit pulp well established, The aqueous extract of T. chebula fruit pulp was tested for its cytoprotective activity. Show, the cultured rat primary hepatocytes and rat whole livers the extract reversed an oxidative injury; caused by tert-butyl hydroperoxide and lactate dehydrogenase leakage significantly. Pharmacological effects, includes against anaphylactic shock, Antispasmodic activity, Gastrointestinal activity, Cardiotonic activity etc
The Minimalistic Metamorphoses-Adamantinoma
Authors: A Bajaj
Published: September 2022

Adamantinoma is an exceptional, primary, malignant, low-grade bone, biphasic, fibro-osseous bone neoplasm of uncertain origin typically constituted of epithelial articulations embedded within a mesenchymal or osteofibrous dysplasia-like stroma. Adamantinoma commonly arises within diaphysis and metaphysis of tibia in addition to ulna, femur, fibula, humerus, radius, ribs, tarsal and metatarsal bones. Adamantinoma depicts a repetitive mutation of KMT2D (MLL2) gene along with fusion of somatic gene EPHB4-MARCH10. Expression of DLK1 gene is enhanced. Adamantinoma is subdivided into diverse categories such as classic subtype, osteofibrous dysplasia-like or differentiated adamantinoma and dedifferentiated adamantinoma. The neoplasm is comprised of epithelial cells with minimal atypia disseminated within an osteofibrous dysplasia -like stroma. Solid nests of basaloid cells with peripheral palisading, tubular structures, clusters of keratinized squamous epithelium or fascicles of spindle-shaped cells are exemplified.
Plasma Cell Leukemia–A Case Report and Review of Literature
Authors: S Nibhoria
Published: September 2022

Plasma cell leukaemia (PCL) is one of the most aggressive and rarest forms of plasma cell dyscrasia. As prognosis is very poor, it is very important to recognize this entity sufficiently early so that one can offer combination chemotherapy at the earliest which can prolong survival.
The TUR Syndrome May Vanish from Urology but will be ReIncarnating as ARDS after Saline Use as Irrigating Fluid in Endoscopic Surgery
Authors: ANM Ghanem
Published: September 2022

Objective: To demonstrate the TUR syndrome characterized with hyponatraemia (HN) will no longer be seen after using saline as irrigating fluid in urology, but it has re-incarnated as the acute respiratory distress syndrome (ARDS) presenting with the same clinical picture of the multiple organ dysfunction syndrome (MODS). Material and Methods: A focussed objective and relevant narrative review of other eminent authors’ work and mine are used here. Results: The TUR syndrome characterized with HN will no longer occur in urology after the use of saline as irrigating fluid in endoscopic surgery. It has reincarnated as ARDS presenting with the same MODS clinical picture. It is induced by VO caused by iv fluid infusions. This induces cardiovascular shock (VOS) that cause ARDS. The latter is already common in clinical practice due to the excessive us of IV fluids in the management of shock, acutely ill patients, and prolonged major surgery as iatrogenic complication of fluid therapy. The wrong Starling’s law dictates the current faulty rules on fluid management of shock that mislead physicians into giving too much fluid. The correct replacement is the hydrodynamics of the porous orifice (G) tube which should be the new scientific basis for fluid therapy in shock management. The currently available hypertonic sodium therapy of 5%NaCl and/or 8.4%NaCo3 is lifesaving therapy for HN, the TUR syndrome and ARDS. Conclusion: The TUR syndrome may seem to have been eradicated in urology with the use of saline as irrigating fluid in endoscopic surgery. However, it has reincarnated as ARDS with the same clinical picture of MODS. It is an iatrogenic complication of fluid therapy dictated by the wrong Starling’s law for which the hydrodynamic of the G tube is the correct replacement that should be the new scientific basis for a new policy on fluid management of shock.
No Added Benefit of Systematic Bladder Biopsies after BCG Induction in High-Risk Non-Muscle-Invasive Bladder Cancer Optimally Managed
Authors: E Xylinas
Published: September 2022

Objectives: To evaluate the added detection benefit of routine transurethral biopsies after an induction course of intravesical Bacillus Calmette-Guérin (BCG) for high-grade NMIBC. Methods: We retrospectively included all patients who underwent white and blue light TURB, subsequent adjuvant induction scheme of BCG, followed by post-instillation biopsies. We excluded patients in whom a prior BCG induction course failed those with synchronous upper tract urothelial carcinoma, and those who did not receive the full 6-week course. A total of 62 patients met inclusion criteria and their records were analyzed. Cystoscopy findings, urine cytology and pathological results of transurethral biopsy were evaluated. Sensitivity, specificity, positive predictive value, negative predictive value, positive and negative likelihood ratios and diagnostic accuracy were calculated for cystoscopy and cytology separately and in combination. Results: After BCG, a total of 342 bladder biopsy were taken with a median of 5 (IQR 2) per case. The biopsy was positive in 13 patients (21%). The median number of positive biopsies was 2 (IQR 1) and the total number of positive biopsies was 27 (8%). The biopsy was positive at the initial tumor site in 8 patients (61.5%). No complications of Clavien III to V were reported. Out of 62 patients who underwent systematic transurethral biopsy, only 3 (5%) presented complications from grade I to II. We found a significant association of positive biopsy with positive urinary cytology (p <0.001) and the presence of erythematous lesions (p <0.02) or visible tumors (p <0.001) at cystoscopy. The pre-BCG stage T (p = 0.32), the presence of CIS (p = 0.71), the multifocal tumor (p = 0.41) and the size (p = 0.52) were not associated with a positive biopsy occurrence. For normal bladder mucosa the predictive value of negative biopsy in cases with negative vs positive cytology was 98% vs 79% (p 0.001). Conclusion: Routine transurethral bladder biopsies after a BCG induction course are not mandatory in the modern era of NMIBC management.
Therapeutic Approach to Erectile Dysfunction - News and Future Perspectives
Authors: BJ Pereira
Published: September 2022

Erectile dysfunction is defined as the inability to get or keep an erection that is sufficient for satisfactory sexual intercourse. It is one of the most prevalent sexual dysfunctions in men, usually correlated with aging. This pathology is generally associated with repercussions in the psychological and social well-being of the patient and his relationship with his partner. This way, it is considered an important cause of a decrease in quality of life. The treatments available today, in most cases, solve the symptoms, however, none of them can reverse the physiopathological basis of erectile dysfunction. In addition to that, they can also interfere with the spontaneity of sexual intercourse, which may be an obstacle to their use. The search for new therapeutic alternatives for erectile dysfunction is in constant development. As sexuality is an important element in human life, an update on these therapeutic advances becomes pertinent, since they could eventually change the paradigm of treatment of this pathology. This work aims to produce a review of the evidence on recent therapeutic advances in erectile dysfunction, as low-intensity shockwave therapy, botulinum toxin treatment, and platelet-rich plasma therapy. This way, a wide bibliography research will be conducted, through online databases and relevant manuscripts.
Assessment of Ureteric Stone Composition Along with Medical Expulsive Treatment of Distal Unilateral Ureterolithiasis in Emergency Department
Authors: F Naeem
Published: September 2022

Background: Ureterolithiasis is among the foremost painful and prevalent among urologic disorders which will substantially impact health-related quality of life. The objective of this study is to provide a brief description regarding ureteric stone composition and treatment of ureterolithiasis. Method: The method of this study was chosen to be cross sectional prospective. The study was carried out in department of urology of Sialkot Medical Complex and Amina Hospital Sialkot cant. Sample size for this study was taken as 200 patients. Well-structured data collection form was prepared, analyzed and then filled by interviewing the patients. Result: The highest occurring stone type was calcium oxalate dihydrate stone (39.5%) and calcium oxalate monohydrate stone (33%). Tamsulosin (96%) was highest recommended for calculus expulsion therapy along with citro soda (90%), diclofenac sodium (76%) and omeprazole (62.5%).
An Appraisal of the Waste Crisis, Urban Floods and Municipal Solid Waste Management in Port Harcourt City, Nigeria
Authors: DN Ogbonna
Published: September 2022

Solid Waste Management (SWM) system has become one of the contemporary issues of the 21st century at all levels. SWM value chain from generation, storage, collection, transportation to disposal requires proper and efficient control. The volume of waste that is generated should be minimized, storage containers should be adequate and suitable, collection should be frequent, transportation vehicles should be appropriate for the purpose and disposal of wastes should be at dumpsites. Municipal Solid Waste management for that matter has become problematic with Port Harcourt as the city is being inundated with so much filth which has proven to be very difficult and seemingly impossible for the municipal authorities to tackle. Efficient MSWM systems require professional management, supported by an informed population and appropriate legislation and policies. This narrative deals to review different waste fractions showing how several sources of pollution are affecting the environment, population health, and sustainable development. This calls for scholars and stakeholders to quantify the comprehensive impacts and plan for integrated solid waste collection, disposal and treatment systems, to improve environmental sustainability at all levels.
Condecorações Estrangeiras
Authors: Pessoa Epitácio , França Marcílio
Published: September 2022

Epitácio Pessoa (Umbuzeiro, May 23, 1865 - Petrópolis, February 13, 1942), an honorary member, benefactor and honorary president of IHGB, was an eminent jurist in the fields of international, private and constitutional law. About a century ago, Pessoa, who had been Justice of the Brazilian Supreme Court and was then President of the republic, presented to the Brazilian Senate a legal opinion commenting on the effects of art. 72, § 29 of the 1891 constitution on the (im)possibility of Brazilian citizens to receive foreign decorations. Due to its historical and doctrinal relevance, we reproduced his opinion here with some comments and notes.
A constituição da propriedade nas décadas finais do Antigo Regime
Authors: Sanches Marcos Guimarães , Lima Rachel Gomes
Published: September 2022

The article investigates the problem of property, or its multiple forms, at the end of the Ancien Régime, taking as case study part of the lands to the Society of Jesus confiscated by the Crown in 1759. Considering that the concept of property as defined by civil law in the 19th century did not yet apply, we understand that there was in the late 18th century a transition to such a concept involving at least two notions of property. Likewise, when studying the configuration of a new landholding structure on the outskirts of the city, we see a quite complex process, deviant from general historiography, related to “large” properties dedicated to export crops such as sugar. The dynamics resulting from the confiscation of the Jesuit lands and their auctioning led to a structure of smaller properties focused on the production of supplies and even on housing, indicating thus the formation of a land market in the region. It is also worth noting that the topic is of interest to the understanding of the formation of the so- called suburbs, a process equally complex and not limited to the displacement of population due to the growth of the city and urban interventions.
EFL University Students’ Attitudes Towards ICT Use for English Language Learning
Authors: Al Arif Tubagus Zam Zam , Hidayati  , Kurniawan Dedy
Published: September 2022

Information and Communication Technology (ICT) has become an essential tool in the field of education, especially for English language learning. This study aims at investigating EFL university students’ perception toward the use of ICT for English language learning. The descriptive quantitative method was applied in this study, which involved 304 students' teachers of English department at a state university in Indonesia. The instrument used in collecting the data was a questionnaire. Descriptive quantitative analysis was used to analyze the data obtained in this study. The result shows that the respondents’ perception was positive in some dimensions. Positive and high perceptions were found in (1) perceived ease of use, (2) perceived usefulness, and (3) attitudes. The results also revealed that the majority of respondents had an ICT device, with YouTube being the most popular activity for English language learning, followed by Google translate and social media.
Implementasi E-Learning di Sekolah Menengah Kejuruan
Authors: Audiva Randi , Rini Faiza , Irsyadunas Irsyadunas
Published: September 2022

Tujuan penelitian ini adalah untuk membantu guru dan siswa dalam proses pembelajaran online. Pada masa  pandemi menyebabkan keterbatasan  waktu tatap muka sehingga proses pembelajaran kurang maksimal, dengan  E-Learning ini dapat membantu siswa dalam mengakses materi dan tugas kapanpun dan baik dengan mengunakan komputer / laptop atau smartphone yang terhubung dengan jaringan internet. Penelitian ini menggunakan model Unified Modeling Languange (UML) dan metode Development Life Cycle (SDLC) yang meliputi 5 tahapan yaitu Planning (Perencanaan), Analysis (Analisis), Design (Perancangan), Implementation (Implementasi), Testing (Pengujian). Untuk proses pembuatan penulis menngunakan Platform Moodle dan server database menggunakan Xampp. Hasil dari penelitian ini berupa sebuah media pembelajaran E-Learning berbasis Moodle yang pengujiannya menggunakan Blackbox testing  yang mana hasilnya valid atau susuai dengan yang diterapkan. Sistem ini dapat memudahkan siswa dan guru dalam melakukan proses pembelajaran pada masa pandemi covid-19.
Rancang Bangun Timbangan Digital Ramah Anak Berbasis Arduino di Posyandu Kota Cilegon
Authors: Islam Saeful , Irwanto Irwanto , Aribowo Didik
Published: September 2022

Dalam proses pelaksaan kegiatan posyandu, ada tahapan penimbangan serta pengukuran tinggi badan balita. Kegiatan tersebut merupakan kegiatan inti untuk mengetahui tumbuh kembang balita serta indikasi stunting. Dilapangan ditemukan penggunaan timbangan yang tidak maksimal serta keluhan dari orang tua balita ketika melakukan proses penimbangan, dimana penimbangan tersebut menggunakan timbangan manual jenis dacin yang digantung disembarang tempat. Dalam proses penimbangan tersebut menimbulkan rasa tidak nyaman, takut serta membuat balita enggan untuk melakukan proses penimbangan bila dimasukan kedalam ayun timbangan yang terbuat dari kain. Selain permasalah tersebut juga ditemukan bahwa kader posyandu mengalami kesulitan dalam proses kalibrasi dan pembacaan hasil sehingga menimbulkan pengukuran yang tidak akurat serta lelah karena balita menangis dan meronta ketika melakukan penimbangan. Oleh sebab itu dilakukan penelitian perancangan serta membuat produk timbangan yang disukai oleh balita, akurat serta mudah digunakan oleh para kader. Pada perancangan alat ini menggunakan sensor loadcell yang difungsikan untuk mengukur berat balita, arduino difungsikan untuk mengatur kontrol dari rangkaian serta coin acceptor yang digunakan sebagai pemeroses input analog berupa coin 1000 rupiah dan menggunakan LCD display digunakan untuk menampilkan hasil dari proses penimbangan. Timbangan ini dikemas dengan bentuk karakter angsa yang ditujukan untuk menarik minat serta membuat balita nyaman dalam proses penimbangan.
Studi Evaluasi Layanan Digital Berbasis Android di SMKN 1 Karimun
Authors: Meliasari Rizki , Mukhaiyar Riki , Ambiyar Ambiyar , Huda Asrul
Published: September 2022

Penelitian ini bertujuan untuk mengevalusi program layanan digital berbasis android yang dilaksanakan di SMK Negeri 1 Karimun. Layanan digital yang dimaksud adalah pelaksanaan ujian digital dan layanan e-raport. Metode yang digunakan dalam penelitian ini adalah metode mix method. Dalam hal ini peneliti mengevaluasi program layanan digital berbasis android di SMK Negeri 1 Karimun yang ditinjau dari kontek, masukan, proses dan hasil. Pengumpulan data secara kuantitatif dan kualitatif. Hasil penelitian ini menjelaskan bahwa pelaksanaan layanan digital yang diterapkan di SMK Negeri 1 Karimun secara umum sudah berada pada kategori baik. Analisis secara konteks program yang dijalankan sudah sesuai dengan rancangan dan tujuan program. Analisis secara input mengungkapkan bahwa upaya penyediaan sarana dan prasana telah diupayakan. Analisis secara proses, layanan digital sudah sangat baik. Analisis secara produk, tampilan dan icon yang ada pada aplikasi sudah cukup jelas dan mudah dipahami.
EFEK POTENSIAL SOAL PENALARAN TIPE TIMSS MENGGUNAKAN KONTEKS BUDAYA LAMPUNG
Authors: Wahyudi Tri
Published: September 2022

The results of the TIMSS study show that Indonesia's rank in mathematics is still low, especially in the cognitive domain of reasoning. This is due to Indonesian students are less accustomed to solve math problems that have a high complexity which demands reasoning skills such as TIMSS problem. The use of context in the exercise of mathematical problems is exactly precise because it is useful in the formation of concepts, access and motivation towards mathematics, modeling, providing tools for thinking using procedures, notations, drawings and rules, reality as the source and application domain, and specific skills training In certain situations. One of contexts that can be used is culture. Mathematics in essence grows from the skill or activity of the cultural environment, so that the mathematics of a person is influenced by his cultural background. This study aims to see the potential effects generated by the problem of specially designed reasoning with the TIMSS problem and using the Lampung cultural context. From the results of the research shows the problems are able to attract interest, motivate and foster the seriousness of students to solve the problem. In addition, these problems are able to elicit students' mathematical reasoning skills, lure students to think harder, more thoroughly, and reason using logic in solving problems.
Enterprise digital transformation and debt financing cost in China?s A-share listed companies
Authors: Sun Changling , Zhang Zixi , Vochozka Marek , Vozňáková Iveta
Published: September 2022

Research background: The rapid development of digital economy has set off a new wave of enterprise reform. Developing the digital economy is not only an urgent requirement of the current situation, but also an important way to meet the people's better life.
Purpose of the article: This paper attempts to reveal the important role of the development of digital technology on the debt financing cost of micro enterprises, and provide micro evidence for the integration of digital economy and real economy. At the same time, this paper wants to provide relevant guidance for formulating digital related policies and reducing the financing cost of the real economy.
Methods: Taking China?s A-share listed companies from 2007 to 2020 as a sample, this paper empirically tests the impact of enterprise digital transformation on debt financing cost and its mechanism. In the robustness test, this paper uses the measures of changing independent variables and dependent variables, instrumental variable method and quantile regression method. In the mechanism test, this paper uses the intermediary effect model. In the further study, this paper uses the method of group regression.
Findings & value added: The study finds that the digital transformation of enterprises significantly reduces the cost of debt financing. Mechanism tests show that the role of enterprise digital transformation in reducing debt financing costs is mainly realized by reducing information asymmetry and alleviating agency problems. Further tests show that the relationship between enterprise digital transformation and debt financing cost is affected by the degree of market competition, whether it is a high-tech enterprise and audit quality. When the degree of market competition is high, the enterprise is a high-tech one, or it is audited by the four major international accounting firms, the effect of enterprise digital transformation on the reduction of debt financing cost is more significant. The method used in this paper is also applicable to the study of other economic management problems. This paper proves a positive significance of digital transformation, which is conducive to promoting the digital transformation of enterprises. Especially for those enterprises in non-high-tech industries, they should speed up the pace. At the same time, this paper has a certain guiding role for the introduction and implementation of policies to encourage digital transformation.
Agribusiness and Food Security: Threats and Issues of Legal Regulation in Martial Law
Authors: Kurman T.V.
Published: September 2022

The article is devoted to researching issues of legal provision of food security and functioning of agribusiness under martial law in Ukraine. The author focuses on the fact that guaranteeing food security is one of the main tasks of every modern civilized state. For Ukraine, which is currently in extremely difficult conditions of martial law, the issues of food security and overcoming the negative consequences of disruption of agricultural production processes are of particular importance. Waging a full-scale war on the territory of Ukraine creates threats in the field of food supply not only for the population of our country, but also for other countries, in particular the countries of Asia and Africa, which are import-dependent on the supply of agricultural products from national producers. Therefore, national agribusiness in modern conditions is not only a type of business activity in the agricultural sector, but also a sphere of social responsibility, which today is taking on a global character.

The state of modern legal provision of food safety was studied, novelties were analyzed and problems of legislative regulation of relations in the specified sphere were identified. It is noted that currently an effective legal mechanism for guaranteeing food security in Ukraine has not been formed. The legislative amendments hastily adopted by the legislator do not form a scientifically based and systematic approach, do not take into account the needs of European integration transformations, the need for strategic reforms in the direction of sustainable development of the agrosphera and countering climate changes that are negative for agricultural production. The possibility of ensuring food security must be guaranteed by the availability of appropriate resources in the agrosphera, its sustainable development, the potential of domestic agricultural production, and the ability to ensure the country's integration into the European and global economic space.

The author comes to the conclusion that the problem of forming an integral mechanism of legal provision of food security in Ukraine is extremely relevant today. This mechanism should include an effective monitoring system with the aim of identifying existing and potentially possible internal and external threats and aimed at solving specific tasks that meet the modern interests and expectations of citizens, territorial communities, Ukrainian society and the state, in particular, in conditions of martial law, as well as contribute to the further improvement of the legislation of Ukraine, the development of science and social progress, which is impossible without guaranteeing the food security of the state and the sustainable development of the agrosphera.
Peculiarities of witness and victim interrogation during investigation of threats or violence against a law enforcement officer
Authors: Kobets S.V.
Published: September 2022

The article reveals the peculiarities of witness and victim questioning in proceedings about threats or violence against a law enforcement officer. The main constituent elements of preparation for conducting this investigative action have been determined. The circle of persons who can act as witnesses in similar proceedings is outlined, and it is established that their list depends on the method and circumstances of commission of this criminal offense. The information that should be established as a result of the interrogation of these persons has been determined. Special attention is paid to tactical techniques of witness interrogation, the choice of which depends on specific investigative situation (investigative materials at disposal of an investigator, characteristics of interrogated person and his interest in results of investigation, the nature of relationship established during the investigative action between investigator and interrogated, etc.). The specifics of interrogation of a witness who is a representative of a law enforcement agency have been determined.

Problematic aspects of interrogation of victims in the investigated proceedings are revealed. It is emphasized that the testimony of this category of witnesses is characterized by completeness and detail, which is caused by the availability of legal knowledge. Acquaintance with regulatory documents regulating the activities of the structure where the victim is employed is recognized as a necessary element of preparation for such interrogations. The list of circumstances to be ascertained during the interrogation of victim law enforcement officer has been defined. Tactical methods that can be used by investigator in various interrogation situations are proposed. It is emphasized that the pronounced conflictual nature of the situation of interrogation of victim in the investigated proceedings usually occurs in case of illegal behavior of law enforcement officer (exceeding official powers, unjustified use of coercion, etc.) on the eve of committing a criminal offense against him. Attention was drawn to the violations that investigators assume when interrogating law enforcement officers as victims.
The law on weapons in Ukraine: a military necessity or a requirement of the time?
Authors: Gretskikh O.V. , Melnyk S.V.
Published: September 2022

After gaining independence at the end of the 20th century and until the start of the active phase of the Russian Federation’s war against it in early 2022, Ukraine inertly treated states with limited civilian access to weapons, remaining the only country in Europe that does not have an appropriate regulatory law, although legislative discussions on this This law has been going on since 1994. Under the conditions of a consistently high level of “armed” crime in Ukraine over the past 10 years, such a law should become a deterrent tool for self-defense of citizens from criminal attacks, and by the beginning of 2022 in Ukraine there were objective prerequisites for the adoption of a modern law on weapons as a framework legislative act in the field of its civil circulation. Today, in the conditions of martial law, the state has a special law on the legal principles of rebuffing the aggressor by civilians using weapons, and the Supreme Council of Ukraine is considering a progressive bill to regulate this area of legal relations. Their essence and conceptual beginnings are analyzed through the study of the concepts of "weapon" and "arms circulation". To this end, the scientific and theoretical understanding of the category "weapon" and its main characteristics have been refined from the point of view of the material essence, the result of the activity and the meaningful purpose. As part of this analysis, it was found that the draft law No. 5708 offers a meaningful modern definition of the concept of "weapon" and the definitions of categories derived from it, which is their first legislative regulation in Ukraine. At the same time, the current Law of Ukraine "On Ensuring the Participation of Civilians in the Defense of Ukraine" does not contain any normative definitions and clarifications, which is explained by the urgent military necessity of a massive rebuff to the enemy's aggression as the conditions in which this legislative act was adopted. The same situation is observed around another fundamental concept of this problem - "arms circulation".
Necip Ali (Küçüka) Bey’in Hakikat Gazetesindeki Yazıları
Authors: ŞAHİNTÜRK Fatma
Published: September 2022

Necip Ali (Küçüka) Bey, genellikle Ankara İstiklal Mahkemelerinin müddeiumumisi (savcı) olması dolayısıyla hukukçu kimliği ile tanınmaktadır. Hukukçu kimliğinin yanında, mecliste beş dönem Denizli mebusu olarak görev almış, halkevlerinde idarecilik yapmış, Ulus Gazetesi, Ülkü Dergisi ve Adliye Ceridesi gibi çeşitli gazete ve dergilerde yazılar kaleme almış ve en nihayetinde de Hakikat isimli bir gazete çıkararak yazı hayatına burada devam etmiştir. Necip Ali Bey’in imtiyaz sahibi ve başmuharriri olduğu, yazı işleri müdürlüğünü Cemal Hakkı Selek’in yaptığı Hakikat Gazetesi, 19 Temmuz 1940 tarihinde İstanbul’da Cumhuriyet Matbaasında basılarak yayın hayatına başlamıştır. Gazete günlük akşam gazetesi olarak siyasi, iktisadi ve edebi içeriklere sahip şekilde dört sayfa halinde yayın hayatını devam ettirmiştir. Başmuharrir olarak Necip Ali Bey gazetede dünya savaşı, savaşa müdahil olan devletlerin politikaları, Türkiye’nin savaşa bakışı, ülke içinde yaşanan iktisadi olaylar ve buna karşı yapılan çalışmalar ile Türkiye nüfusuna dair düşüncelerini kaleme almıştır. Hakikat gazetesi, yoğun olarak savaşa müdahil olan devletlerin politikaları, savaşın genel seyri ile ülke içinde ve dışında yaşanan birçok meseleye yer vermiş olan günlük akşam gazetesidir. Çalışmada Hakikat Gazetesinin 19 Temmuz 1940-31 Aralık 1940 tarihleri arasında yayımlanmış olan tüm sayıları incelenmiş ve Necip Ali Bey’e ait tüm yazılar okunarak değerlendirilmiştir.
CRISIS OF LANGUAGE: SEMANTICS IN GOD-DISCUSSION OF THE FATHERS
Authors: JAMIR Chongpongmeren
Published: September 2022

The early Christian discussion on the doctrine of God occurred primarily within the Hellenistic culture. Christians borrowed both concepts and religious and philosophical vocabularies from the existing culture to appropriate their faith. These concepts and vocabularies have inherent meanings associated with them. Thus, a Hellenization of Christianity has been argued for in the existing literature. On the other hand, baptizing them into Christian usage also resulted in a dehellenization of the cultural concepts and vocabularies. This essay focuses on the linguistic aspect of the interaction of Christianity with culture during its early years. It argues that Patristic discussion on God and Godhead needs to be understood within the dynamics of the crisis of language and the semantic differences that accompanied patristic appropriation of the Christian faith.
Nanotechnology and the application in the food industry
Authors: Ojeda Gonzalo Adrián , Arias Gorman Adriana María , Sgroppo Sonia Cecilia
Published: September 2022

The application of nanotechnology in the food industry enables prioritization of consumers’ needs. Nanotechnology has the ability to provide new forms of control on food structure; therefore, this technology has higher industrial value. This paper briefly introduces the main concepts of nanotechnology and its correlation with size reduction performance. This paper also introduces the main nanobjects and their potential applications in food, and summarizes various studies and their applications in food industry.
Fringing Field Analytical Calculation of High Frequency Planar Magnetic Components
Authors:   Beijing Jiaotong University, Tian Ye
Published: September 2022

When the switching frequency is above 100 kHz, the winding loss of the round wire magnetic component will increase sharply due to skin effect and proximity effect, which greatly limits its wide application. On the contrary, the planar magnetic component can not only work at such high frequency, but also suitable for high power density applications for its low profile. However, in order to avoid core saturation and change the inductance, the air gap is usually required in the design of the planar magnetic component, which will produce fringing effect and further increase the winding loss. Based on Roshen’s assumptions, this paper analyzes the planar magnetic component with center air gap. Firstly, the Schwartz-Christoffel mapping is used to establish the mapping relationship between the air gap fringing region and the strip region. Then the magnetic field intensity in complex form is obtained by the complex potential function and the one in vector form is given, which is represented by the strip region coordinate. Finally, the magnetic field intensity verification and the thermal verification are carried out. The method proposed in this paper provides effective guidance for the design of planar magnetic components operating at high frequency.
A Data-Driven Self-Learning Evaluation Method of Voltage Sag Severity
Authors:   the Electric Power Scientific Research Institute of State Grid Henan Province Electric Power Company, Liu Shuming
Published: September 2022

Lightning is one of the main causes of voltage sags, and it is of great significance for subsequent analysis and governance to accurately evaluate the severity of the sag events caused by lightning. There are many uncertain factors between lightning fault events and voltage sag events. To evaluate the severity of voltage sag events caused by lightning, a data-driven self-learning evaluation method for voltage sag severity is proposed. According to a large number of online monitoring data of lightning positioning system and power quality monitoring system, the association rule mining algorithm based on incremental learning is used. And the rules are kept updating through the accumulation of historical data, which may give it the abilities of self-learning. The empirical analysis is carried out based on the monitoring data of a regional power grid. The results show that the method in this paper can accurately mine more valuable rules in reality and solve the problem of low efficiency of mining algorithm when the database changes dynamically.
Innovación docente en el estudio de la imagen
Authors: Mocholí Martínez María Elvira
Published: September 2022

Introducción al dosier
Systemic Risk of The Vietnamese Commercial Banks: A New Approach Using CoVaR and SRISK Measurements
Authors: Lê Hải Trung , Đỗ Thu Hằng , Tạ Thanh Huyền
Published: September 2022

One of the main lessons of the global financial crisis in 2007–2009 is keeping individual financial institutions sound would be not enough for the stability of the financial system, given the increasing complexity of the banking activities and systemic risk. In this paper, the authors measure the systemic risk of 12 listed Vietnamese commercial banks from April 2008 to June 2021 based on two market risk measures, namely the CoVaR and SRISK. The use of market price in the estimation of bank systemic risk results in timely and forward-looking risk measures, which is particularly important during volatile periods. The authors also provide several policy discussions on the measurement and supervision of systemic risk in the Vietnamese banking sector.
Benefits of physical activity on cardiometabolic diseases in obese children and adolescents
Authors: Gao Juan , Lu Yi , Gokulnath Priyanka , Vulugundam Gururaja , Li Guoping , Li Jin , Xiao Junjie
Published: September 2022

In the past few decades, obesity in the pediatric population has dramatically increased and is common in many countries. Childhood obesity often causes health problems and increases the risk of cardiometabolic diseases such as type 2 diabetes, nonalcohol fatty liver, and cardiovascular diseases. Obesity in young people has been closely associated with environmental, behavioral, and genetic defects, including the availability of high-energy and sugary food and beverages, sedentary behavior, and hereditary factors. Few drugs are currently available to treat obesity in children and adolescents because it is difficult to demonstrate the safety of these drugs on the growth and development of the youth. Lifestyle modifications, such as diet control and physical exercise, are the primary approaches for preventing and treating childhood obesity. Among them, physical activity is a crucial component. This review summarizes the epidemiology, cardiometabolic risk of obesity, therapeutic strategies, and the benefits of exercise on obesity-related chronic diseases in children and adolescents.
Effects of Weight-Bearing and Weight-Supporting Sports on Bone Mass in Males
Authors: Długołęcka Barbara , Jówko Ewa
Published: September 2022

Introduction.
The aim of this work was to assess bone mineral content (BMC) and bone mineral density (BMD) in male athletes performing weight-bearing and weight-supporting sports activities as well as in untrained men.

Material and methods.
The study included 140 men aged 20-23. The study group consisted of wrestlers, football players, cyclists and untrained men. BMC (g) and BMD (g/cm2) in the lumbar spine (L2-L4) were determined with the use of the DEXA method. Biochemical parameters (concentration of osteocalcin, testosterone and 25-OH vitamin D in blood) were measured using the ELISA method. Diet composition was assessed based on three individual questionnaire interviews regarding nutrition in the last 24 hours prior to the study.

Results.
Statistical analysis revealed that wrestlers demonstrated the highest levels of parameters related to bone mass. In this group, mean values of BMC, BMD as well as BMD compared to peak populational bone mass were significantly higher than in cyclists and the men from the control group. In the case of BMD (g/cm2), the difference was at the level of p < 0.001, whereas in the remaining parameters, i.e. BMC (g) and BMD with reference to age (%), it was at the level of p < 0.01. No significant differences between the groups were observed in the concentration of osteocalcin, testosterone and 25-OH vitamin D in blood and in nutrition.

Conclusions
. Athletes who perform sports that predispose to the development of bone pathology should also do exercises that would support bone mineralisation and prevent osteoporosis in the future.
Perception of Innovations by Primary Education Teachers: Case Study of Bilingual Classes in Moscow and Moscow Region
Authors: Koroleva A. A. , Nikiforova A. N. , Novikova L. D.
Published: September 2022

The article considers the balance of tradition and innovation as forms of cultural dynamics using the example of education. The review of scientific publications published in 2020-2021 has found that the research interest in the topic is characteristic both of Russianand Spanish-speaking authors, which allows us to refer to international experience, mainly Spanish, for comparison. In this research the authors focus on the project of bilingual classes in primary schools in Moscow and Moscow region. The idea of bilingual education is that educational material is presented in two languages, yet the language pairs can vary: official and minority, official and migrant, official and foreign languages. In the context of the case study, teachers of primary education constitute the most promising group due to the structural features of this level. The system in which one teacher is responsible for most of the subjects allows the project to be implemented gradually without involving a large number of pedagogical staff. At the same time, a teacher of a bilingual class has an opportunity to develop an independent teaching strategy, demonstrating a high level of methodological freedom. The survey among the teachers found that while there is a demand for counseling on their part, they are motivated and receptive to innovations.