bluuebunny/crossref_metadata_2025 huggingface dataset:
EXPERIENCES OF MALAYSIANS RECOVERING FROM SUBSTANCE USE DISORDER WITHOUT FAMILY SUPPORT: A PHENOMENOLOGICAL STUDY
Authors: Hsia Julie Tay Gek , Yusoff Nur Hafizah , Abdullah Azlina
Published: September 2024

Substance use disorder recovery often involves a complex and diverse path influenced by numerous circumstances, making it a unique journey for each person. This study provides a deeper examination of individuals who have undergone the recovery process without familial assistance, examining alternative support networks, coping mechanisms, and the overall impact of the recovery journey on their lives. The objective is to comprehend the strategies employed by these individuals in their recovery process and the role of internal motivation, external factors, and peer support in fostering positive change. This study employs a qualitative phenomenological approach, using purposive and snowball sampling to recruit and conduct semi-structured interviews with six individuals. The research indicates that coping with loss and yearning during recovery plays a pivotal role in influencing individuals’ decisions to change, with internal motivation, external factors, and peer support being identified as interconnected drivers of positive change. Recognizing that people in recovery encounter various situations that may impact their journey suggests that individualized and adaptable policies should be provided according to each person’s needs and experiences. This study contributes novel insights into the recovery process without family support, emphasizing the need for adaptable support strategies in substance use disorder recovery.
A MODEL OF STUDENTS’ INTEREST IN STOCK INVESTMENT WITH RISK PERCEPTION AS A MODERATION
Authors: Kristiana Ida , Pangestu Amanda Agi , Agung Ery Wibowo , Janie Dyah Nirmala Arum , Nurcahyono Nurcahyono
Published: September 2024

This research aims to determine the factors that influence students’ interest in investing in shares, both directly and indirectly. These factors include investment knowledge, financial literacy, investment motivation, technological advances, and are moderated by risk perception. The population of this research is students in Semarang City in general and students who are members of KSPM. Samples were taken using the purposive sampling method, namely 300 respondents. The data analysis technique used is path analysis assisted by WarpPLS 7.0 software. The research results show that investment knowledge has a negative effect. Financial literacy, investment motivation and technological progress have a positive effect on students’ stock investment interest. Then the risk perception variable weakens the relationship between investment knowledge and technological progress on students’ stock investment interest. Furthermore, the risk perception variable strengthens the relationship between financial literacy and investment motivation on students’ stock investment interest.
THE IMPACT OF PUBLIC RELATIONS ON STRENGTHENING EDUCATIONAL INSTITUTIONS’ REPUTATIONS: KING KHALID UNIVERSITY AS A MODEL
Authors: Khasawneh Mohamad Ahmad Saleem
Published: September 2024

This study aimed to explore the role of public relations in enhancing Saudi Universities’ reputation. This study focused on King Khalid University as a model. The study used descriptive methodology and designed a questionnaire as an instrument to collect data from a sample of 88 faculty members from different faculties at the university. The results indicated a relationship between public relations and the dimensions of an organization’s reputation (social responsibility, quality of service), and there was no relationship between public relations and the creative skills dimension. The findings revealed an important role for public relations in enhancing the reputation of an organization, indicating the necessity of applying public relations activities and taking care of various audiences at the educational level. The findings also revealed universities’ willingness, especially King Khalid University, to invest in public relations matters to strengthen their reputation.
PREDICTING THE PROGNOSIS OF COVID-19 PATIENTS BASED ON CHEST X-RAY AND CLINICAL DATA
Authors: Alzu’bi Amal , Mustafa Omara , Najadat Hassan
Published: September 2024

The rapid emergence of COVID-19 resulted in a pandemic that affected the well-being of millions of people. This research aims to help hospitals in Jordan forecast the prognosis of COVID-19 patients at the early stages using machine learning algorithms, which can promote their ability to build and assess strategic planning and decision making. We applied several machine learning algorithms to predict the prognosis of the admitted COVID-19 patients at early stages and classify the infected cases according to their severity of illness and other factors and then recommend the appropriate level of care, including ICU, intermediate, or general floor, using objective measures without any subjective evaluation by physicians. A total of 153 COVID-19 patient records were collected from King Abdullah University Hospital (KAUH), including demographics, comorbidities, length of stay, laboratory tests, chest x-ray severity score, and level of care. The results demonstrate that the highest F1-score was achieved by the XGB classifier (99% on average across different levels of care, followed by the gradient boosting classifier and SVM (97% and 96.6% respectively. In conclusion, our research can help reduce medical errors and improve patient safety. Additionally, it can significantly reduce the length of stay of patients.
Problems and prospects of the functioning of agricultural chains in the meat breeding of Ukraine
Authors: Ibatulin Ildus , Nedaskivsky Volodymyr , Golembivsky Serhiy , Artimonova Iryna , Prysiazhnyuk Natalia
Published: September 2024

Introduction. In the meat balance of Ukraine, beef and veal have a decisive place, which cannot be replaced, since each of these types of meat has specific taste properties, amino acid composition and nutritional value. However, a sharp decline in the production of livestock meat products during the years of market transformations led to a significant reduction in the population's consumption of beef and veal against the background of a decrease in the supply of domestic meat and a significant increase in its imported supplies in frozen form. The problem can be successfully solved only through the development of specialized meat cattle breeding.
Method (methodology). To implement the tasks set in the article, the following methods and techniques were used: monographic and graphic - for a comprehensive study of the current state of production of meat and livestock products and the determination of factors affecting its effectiveness; selective - for a detailed survey of individual livestock farms; abstract-logical, calculation-constructive and balance - when justifying indicators of the development of production and consumption of beef and veal for the future, as well as the size of state support.
The results. On the basis of the conducted research, it was established that measures to fundamentally improve the situation in all segments of animal husbandry and raw meat processing are necessary to ensure food independence and security of Ukraine. The industry requires significant financial support from the state, including by reducing credit rates, timely payments of subsidies, regulation of foreign trade in livestock products, and ultimately increasing the competitiveness of domestic meat both on domestic and foreign markets. Given the low demand for beef in the domestic market as a result of the low purchasing power of the population and food culture, the main vector for the sale of cattle is export. For this purpose, at the state level, measures aimed at increasing the export potential in beef cattle breeding have been proposed.
Comprehensive Analysis of the Effectiveness of Omnichannel Marketing Strategy in Increasing Sales Optimization in Companies
Authors: Sutomo Sutomo
Published: September 2024

This study aims to evaluate the effectiveness of omnichannel marketing strategies in optimizing a company's sales performance. By integrating online and offline sales channels, omnichannel strategies provide a seamless customer experience. This study uses a quantitative approach with a descriptive-analytical method to analyze the relationship between omnichannel strategy and sales performance. A sample of 150 retail companies was selected through purposive sampling, ensuring that only companies implementing a comprehensive omnichannel strategy were included. Data collection was conducted through structured surveys and secondary sources, where respondents rated the strategy's effectiveness using a 5-point Likert scale. The results showed a significant increase in sales performance, with an average increase of 18% in the surveyed companies. In addition, customer satisfaction and operational efficiency were found to act as moderating variables in the relationship between omnichannel strategies and sales performance. This study concludes that omnichannel marketing strategies effectively increase sales and customer satisfaction, with recommendations for further research and practice focused on improving inventory management and technology integration.
tradition of catch marriage at Sumba from a human rights perspective
Authors: Bire Chatryen M. Dju , Jacob Yossie M. Y. , Nubatonis Orpa J. , Lamataro Cyrilius W.T.
Published: September 2024

Purpose: Marriage must be based on the willingness of each party to become husband and wife to form a happy family without any coercion from any party. If a marriage is entered into without the consent of both parties, the marriage can be a reason to cancel the marriage. Arrest marriage is a process where a woman is taken by force or violence by a man to become his wife and then carries out a traditional procession through the replacement process. The purpose of this writing is to look at the tradition of capture marriage that occurs on Sumba Island from a human rights perspective.
Research Methodology: The method used is normative research.
Results: The results of the research show that a woman who is already under the control of a man (in this case married and arrested) no longer needs his consent whether she agrees or not to be taken and used as a wife. This is of course in conflict with Article 2 of the Marriage Law where the consent of the parties, both the man and the woman, is the main thing. Arrested marriages which are carried out by not giving a woman the freedom to determine with whom she will build and maintain a household are a violation of human rights. Article 1 of the Human Rights Law provides an understanding relating to human rights violations, namely every action of a person or group of people, including state officials, whether intentionally or unintentionally, taking or depriving human rights. From a human rights perspective, it is clear that any type of action that causes torture and fear, both physically and spiritually, is a violation of human rights.
Influence of work facilities, competency, communication on business participants' satisfaction through service quality as a variable intervening at investment and one door opening service of the province of the Riau Island Government
Authors: Hendrayani Lili , Wibisono Chablullah , Satriawan Bambang
Published: September 2024

Purpose: This study aimed to analyze the effect of Work Facilities, Competence, and Communication on Business Satisfaction through Service Quality as an intervening variable at the Investment and One-Stop Integrated Service Office of the Riau Islands Provincial Government, totaling 168 employees.
Research Methodology: The sample used in this study was the entire population of 168 employees of the Investment Service and One-Stop Integrated Service of the Riau Islands Provincial Government. In this study, the sampling technique used was nonprobability sampling with the technique taken, namely saturated sampling (census). The research method uses a quantitative approach with the analysis of partial least squares (PLS) analysis techniques with SmartPLS version 4.0.
Results: The results indicate that Work Facilities have a positive and significant effect on satisfaction. Competence has a positive and insignificant effect on satisfaction. Communication had a positive and insignificant effect on satisfaction. Service Quality had a positive and significant effect on satisfaction. Work facilities had a positive and significant effect on service quality. Competence has a positive and significant effect on Service Quality. Communication has a positive and significant effect on Service Quality. Service Quality does not mediate the influence of Work Facilities on Satisfaction. Service Quality mediates the influence of Competence on Satisfaction. Service Quality mediates the influence of Communication on Satisfaction.
Analysis of customer satisfaction of regional drinking water company Tirta Mulia Karimun the Riau Islands
Authors: Ngaliman Ngaliman , Rafiza Raja , Khaddafi Muammar
Published: September 2024

Purpose: The purpose of this study was to determine and analyze the indirect effect of leadership on burnout among Riau Islands Province Regional Secretariat Employees. To determine and analyze the indirect effect of Workload on burnout of Riau Islands Province Regional Secretariat Employees. To determine and analyze the direct effect of emotional factors on burnout of Riau Islands Province Regional Secretariat Employees. As a regional company that provides basic clean water services for the Karimun Regency community, PDAM Tirta Mulia Karimun should provide customer satisfaction. However, many customers still complain about water quality and limited volume. This study aims to determine the effects of quality, volume, tariffs, and services on customer satisfaction.
Research Methodology: This study used a quantitative method. The sample consisted of 200 respondents who were analyzed using the SMARTPLS program. After validity and reliability tests were conducted, a hypothesis test was conducted.
Results: The results showed that quality, volume, and service had a significant direct effect on customer satisfaction. Tariff had an insignificant direct effect on satisfaction. Product quality has a significant direct effect on PDAM services. Volume had a significant direct effect on service. Tariffs have a significant direct effect on PDAM services. Product quality had a significant effect on customer satisfaction through PDAM Tirta Mulia Karimun services, with a P value of 0.001 <0.05. Volume has a significant effect on customer satisfaction through services, with a P value of 0.001 <0.05. Tariffs have a significant influence on customer satisfaction through PDAM Tirta Mulia Karimun services, with a P value of 0.008 <0.05. Customer satisfaction is influenced by product quality, volume, and tariffs by 70.4%. This study concludes that the variables studied, namely, quality, volume, tariff, and service, have a significant influence on customer satisfaction. The dominant improvements that must be made are related to quality and volume.
Prediction of financial distress in transportation and logistics companies before, during and after the Covid-19 pandemic listed on the Indonesia Stock Exchange
Authors: Dewi Sinta
Published: September 2024

Purpose: This study aims to predict financial distress in transportation and logistics companies before, during, and after the Covid-19 pandemic.
Research Methodology: The research subjects were 23 companies, and the study utilized an artificial neural network model. This study uses financial ratios, including the debt-to-asset ratio (DAR), Current Ratio (CR), and Return on Assets (ROA) as input variables in the artificial neural network architecture. The objectives of this study are to calculate the three ratios used as test data, determine the differences in financial ratios between companies reported as financially distressed and those not experiencing financial distress in the training data, identify the artificial neural network model architecture that produces good performance on the training data sample for use in testing predictions, and predict financial distress using an artificial neural network on transportation and logistics companies listed on the Indonesia Stock Exchange, which are part of the research sample. The research sample consisted of 20 transportation and logistics companies listed on the Indonesia Stock Exchange from 2015 to 2019.
Results: The results reveal that companies reported as financially distressed have lower average values for the three ratios compared to companies not experiencing financial distress, making them suitable input variables. The best artificial neural network architecture in this study included an input layer with 60 neurons, a hidden layer with 15 neurons, and an output layer with one neuron. This architecture achieved a training performance mean square error (MSE) of 0.125004 and an R value of 50.00%. The study's findings suggest that 12 companies are predicted to experience financial distress.
Navigating Bilingualism: Exploring Language Dynamics in Indonesian Children Reluctant to Speak With Parents Using Foreign Language
Authors: Rahman Muhammad Arinal
Published: September 2024

Despite the acknowledged benefits of bilingualism in children's language development and executive functioning, a significant gap persists in understanding instances where bilingual children actively avoid using their acquired language skills with their parents. This study addresses this gap by examining the factors contributing to the reluctance of Indonesian children proficient in foreign languages to speak them with their parents. Through qualitative exploration deeply embedded in the participants' cultural and linguistic context, the research focuses on parental influence and intergenerational dynamics. This theme underscores parents' pivotal role in shaping bilingual children's language choices and preferences, revealing insights into their tendency to avoid speaking a foreign language. The complex dynamics of language dominance and exposure in bilingual families, influenced by factors such as parental beliefs, language policies, and the broader sociocultural context, are explored. The interplay between parental guidance and a child's preferences underscores the intricate nature of language dynamics within the family. Additionally, the study examines how navigating multicultural environments within bilingual families significantly impacts bilingual children. This unique case sheds light on how parental influence and cultural exposure jointly shape a child's bilingual language preferences, providing a nuanced understanding of language choices within a family setting.
Speaking with Distance: Exploring the Effectiveness of Remote Practice
Authors: Tauchid Ahmad , Seftika  , Zumrudiana Ainu , Suwandi Edi
Published: September 2024

The rising prominence of remote speaking practice in education and professional development underscores its critical significance. Enabled by advancing technology, remote platforms offer unprecedented convenience and accessibility for individuals to refine speaking skills. Research explores the efficacy of remote speaking practice, drawing on previous studies that have examined technology-mediated communication for language learning and public speaking training. Building on this foundation, this study investigates students' perceptions of remote speaking tasks' impact on pronunciation, speaking skills, and confidence. Through a qualitative approach involving open-ended surveys distributed to 19 English students at one of the Islamic private universities in Indonesia, attitudes and motivations shaping students' perspectives are explored. Analysis using NVivo 12 highlights the pivotal role of remote speaking tasks in improving pronunciation skills and fostering English speaking proficiency. Moreover, students' recognition of confidence as integral to successful language learning underscores the importance of supportive learning environments. The findings underscore the necessity of integrating remote speaking tasks into language curricula to enhance pronunciation and speaking proficiency effectively while emphasizing the pivotal role of confidence in facilitating language acquisition. These insights hold significant implications for language education, advocating for the incorporation of remote speaking practice to empower learners in developing fluency and proficiency in virtual environments.
Ruptura Esplénica en gestante como debut de Leucemia Mieloide Crónica: Reporte de un caso y revisión de la literatura
Authors: Seminario-Marcelo Victor Ernesto , Cueva-Salazar Martha Isabel , Luperdi-Rodríguez Marisela Liz , Mesta-Cornetero María Luisa , Salazar-Carrillo Karina , La Torre-Matuk Alejandra
Published: September 2024

Se reporta el caso clínico de una paciente de 34 años en semana 30 de gestación, que debuta con Leucemia Mieloide Crónica (LMC) complicada por una ruptura esplénica aguda secundaria a esplenomegalia masiva. Inicialmente ingresa por dolor abdominal y hallazgos de laboratorio compatibles con LMC en fase crónica. Recibe tratamiento conservador por precaución de efectos teratogénicos. Al día 7 presenta deterioro clínico con sufrimiento fetal, encontrándose en laparotomía exploratoria un hemoperitoneo masivo por laceración esplénica de 12 cm. Se realiza esplenectomía de urgencia y cesárea, con recién nacido sano. La paciente evoluciona favorablemente. Este es el primer caso reportado de rotura esplénica como debut de LMC gestacional. Se discuten los desafíos terapéuticos ante el riesgo fetal de los inhibidores tirosina quinasa, y la importancia de un abordaje interdisciplinario hematología-obstetricia-cirugía para optimizar resultados maternos y neonatales.
ONCOGENIC VIRUSES: A SHORT REVIEW
Authors: Badari Rao Karanam
Published: September 2024

Viruses that cause neoplasia are called oncogenic viruses. Identication of oncogenic viruses in humans
is a complex process and has intrigued researchers over the years. Functional analysis of protein
sequences expressed during viral infection continues to provide clues to its persistent nature, as well as reactivation and
malignant transformation. Understanding the relationship between viruses and neoplasia and implication of viruses to specic
cancers is important for the prevention and treatment of virally induced tumors and diseases.
ABDOMINAL SKIN INCISION CLOSURE WITH NON- ABSORBABLE SUTURES VERSUS STAPLES- A COMPARATIVE STUDY
Authors: Roby Calvin , Chandra Satish , M Rai Likhith , J Jangamashetty Shivakumar , G Hegde Yatish , Mulla Hind Noorudheen , R Chinya Sanskriti
Published: September 2024

The act of sewing is as old as Homo sapiens. In Susruta
Samhitha 600 BC there is mention of suture material made
from animal sinews, braided horsehair, leather strips, and
vegetable bers.
CLINICAL CHALLENGES AND MANAGEMENT OF HYPERLEUKOCYTOSIS AND LEUKOSTASIS IN HEMATOLOGIC CANCERS
Authors: Diaz Diaz Miguel Angel
Published: September 2024

Hyperleukocytosis is dened as a white blood cell (WBC) count exceeding 100,000/microL in patients with
leukemia, particularly acute myeloid leukemia (AML). Leukostasis, or symptomatic hyperleukocytosis,
results in microvascular occlusions causing respiratory distress, central nervous system abnormalities, and organ dysfunction.
The epidemiology varies, with hyperleukocytosis frequently observed in AML, affecting up to 20% of newly diagnosed patients,
and less commonly in other leukemias. The pathophysiology involves increased blood viscosity and endothelial adhesion,
leading to tissue hypoxia. Clinical manifestations include neurological and respiratory symptoms, necessitating early
recognition and intervention. Treatment involves cytoreductive therapy, supportive care, and monitoring, aiming to reduce the
high initial mortality associated with leukostasis.
UNIQUE OBSTETRIC CHALLENGES: UNICORNUATE UTERUS WITH STOMA AND SUCCESSFUL MANAGEMENT OF POSTNATAL BURST ABDOMEN
Authors: F Lewis Preeti , Bendale Rucha , Thathira Swati , Surpatne Vaishnavi
Published: September 2024

Living with a permanent stoma has negative and stressful impact on patient's mind, health and body and
having a pregnancy in such a condition is challenging for patient as well as treating obstetrician to give
the best possible management and provide meticulous care to prevent further complications. Past studies have focused on
fertility and conception but data on patient experience and outcome of pregnancy after stoma surgery is scarce . Such patients
not only require meticulous post op care for preventing complications due to stoma but also psychosocial counselling to comply
by the treatment . Future research is needed on the impact of surgical complications on psychology of the patient such as anxiety,
depression and post-traumatic stress, as well as on how to support patients who experience a complicated postoperative
recovery. Here is an exceptionally rare case of unicornuate uterus associated with dorsal pancreatic agenesis with colostomy
done in a case of anorectal malformation with disuse atrophy of distal loop of colon with cystic lymphangioma with
postoperative burst abdomen managed successfully
CURRENT STRATEGIES IN TREATING AND PREVENTING SPONTANEOUS BACTERIAL PERITONITIS IN ADULTS
Authors: Perez Correa Juan Felipe
Published: September 2024

Spontaneous bacterial peritonitis (SBP) is a life-threatening infection in patients with cirrhosis and
ascites. Early recognition and prompt treatment with empirical antibiotics, albumin administration, and
supportive care are essential to improve outcomes. This review discusses the pathogenesis, clinical manifestations, diagnosis,
treatment, and prevention strategies for SBP, emphasizing the importance of timely intervention. Preventive measures, including
secondary prophylaxis with antibiotics, are recommended for high-risk patients to reduce recurrence rates. Enhanced
diagnostic techniques and tailored treatment approaches are critical for managing SBP effectively.
LAPAROSCOPIC VAGINOPLASTY PROCEDURE USING A MODIFIED PERITONEAL PULL-DOWN TECHNIQUE WITH UTERINE BUD FLAP IN PATIENTS WITH MAYER–ROKITANSKY–KÜSTER–HAUSER SYNDROME.
Authors: Patel Paulomi , Kendre Kranti , Mandade Krishna
Published: September 2024

Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is a
congenital malformation characterized by the defective
development of the Müllerian ducts resulting in the absence of
a functional vagina and uterus in the presence of normally
functioning ovaries. [1] As a result, conception and vaginal
sexual activity are compromised. In patients with MRKH
syndrome, the creation of a neovagina allows for satisfactory
sexual intercourse, and uterus transplantation (UTx) can
allow patients with MRKH syndrome to give birth. [2] Several
surgical and nonsurgical techniques for creating an
adequately sized and functional neovagina to allow for
sexual intercourse have been developed for patients with
MRKH syndrome. [3],[4] However, the surgical method with the
best anatomical and functional outcomes is controversial due
to a lack of comparative studies. In addition, various materials
have been used to cover the newly created space. The
laparoscopic Davydov procedure is one of the most commonly
used techniques, in which multiple complications have been
observed.[5,6] Therefore, various modied laparoscopic
procedures have been developed.[7,8,9] In this report, we
describe a novel laparoscopic vaginoplasty procedure, using
a pull-down technique of the peritoneal aps with additional
structural support to the neovaginal apex using the incised
uterine bud in patients with MRKH syndrome and report the
anatomical and functional outcomes of our case series. [10]
UNVEILING RISKS: A DETAILED REVIEW OF CALCIUM HYDROXIDE ACCIDENTS IN ENDODONTIC THERAPY
Authors: Vandekar Mansi , Pendse Gayatri , Toprani Nikita , U Hulyal Shreya , Misra Rashmi , Shah Anuja
Published: September 2024

Calcium hydroxide paste is widely used as a provisional root canal lling material. When extruded
inadvertently into the periapical region, it may lead to several complications. Clinicians should remain
vigilant regarding the extrusion of intracanal medicaments and the potential for injury to the maxillary sinus or inferior alveolar
canal. Care must be taken when administering calcium hydroxide into the canal to prevent any injury to the underlying nerves.
These accidents, arising from various factors such as incorrect placement techniques and inadvertent extrusion, manifested a
spectrum of complications, from minor discomfort to signicant tissue damage. Management of these incidents necessitated
meticulous interventions and occasionally surgical procedures to address the severe consequences. It underscores the critical
role of precision and interdisciplinary cooperation in managing calcium hydroxide accidents effectively
SPINAL TUBERCULOSIS: ROLE OF MRI IN DECIDING THE DURATION OF ANTITUBERCULAR THERAPY
Authors: Shinde Mahesh , Patel Mihir , Das Gupta Bibhas , Sharma Atharva , Upadhyay Dheer , Chiwadshetti Shreyasi , Patil Yogeshwari , Dhage Tejas , Kowe Chhavi , Charolia Abdullah , Rajesh Dhayalkar Komal , Chavan Praful
Published: September 2024

Introduction: The most common extrapulmonary location of TB is the spine, accounting for more than
50% of musculoskeletal TB. MRI is the most valuable method for detecting early disease and is the
preferred technique to dene the activity and extent of infection. It is also considered the imaging modality of choice for followup of tuberculous patients managed by operative or nonoperative treatment of tuberculous spine. Follow-up MRI can make a
big difference in spinal tuberculosis; it can clearly show the change in the vertebral body and intervertebral space, paraspinal
abscess, and the kyphosis angle after the treatment, which can provide a reference for clinical treatment and estimating
prognosis. Role of MRI in deciding stoppage of anti-tubercular treatment in spinal tuberculosis. Aims and Objectives:
Materials and Methods: This is a retrospective and prospective observational study on 62 patients of all ages and either sex of
spinal TB who sequentially underwent MRI pre-treatment and every 6 months after starting treatment till complete resolution.
Results: Out of 62 spinal tuberculosis patients, higher incidence is noted in females (42 patients,65%) with the most common
age group affected being 21 to 30 years (20 patients,32%) with predominant involvement of thoracic spine (35 patients, 56.5%)
followed by lumbar spine (16 patients,25.8%) and cervical spine (3 patients,4.8%), with 8 patients (12.9%) having skip lesions.
Of 62 patients, 34 (54.8%) were positive for gene expert, and 17(27.4) were positive for culture. 36 (56%) patients underwent
decompression and instrumentation, and 26 (46%) were managed conservatively. At the end of the study,42 patients showed
complete or near complete resolution. A total (42 patients,67.7%) had stopped AKT based on MRI resolution. The remaining 20
patients (32.3%) with partial and no resolution were continued on AKT for 18 months. MRI is the bes Conclusion: t modality to
diagnose and monitor response to antitubercular treatment and is the best modality to stop antitubercular therapy depending
upon complete resolution.
EFFECT OF HEMODIALYSIS ON OUTCOME OF COVID 19 PATIENTS WITH RENAL FAILURE
Authors: Gupta Rahul , Yadav Sns , Singh Gk , Singh Rr
Published: September 2024

Background & Objectives: COVID19 has the capacity to injure organs such as the heart, nervous system,
or the kidney besides causing interstitial and alveolar pneumonia1,2. Acute Kidney Injury (AKI) is an
independent risk factor for mortality in Covid 19 and is the most frequent extra-pulmonary organ dysfunction associated with
ARDS. CKD patients have worsened Covid 19 outcomes due to increased risk of infection-related mortality as a consequence of
impaired immunity. However, data comparing AKI and CKD patients on Maintenance Haemodialysis (MHD) in Covid-19 are
sparse. So we undertook this study. The purpose of this present work was to evaluate the Effect of Haemodialysis on Outcome of
Covid 19 Patients with Renal Failure in a tertiary care hospital in rural settings during the 1st and 2nd wave of Covid – 19
pandemic. Methodology: 342 eligible Covid 19 patients were selected from case les of patients admitted during rst and
second wave of Covid 19 at our institute from July 2020 to June 2021. These patients were divided into two groups viz. patients
with renal failure (n=171) and without renal failure (n=171). Those with RF were further subdivided into CKD & AKI (n=49 &
n=122 respectively). Outcomes were compared in both the groups and intragroup analysis was also done. Results: We found
that, in patients with Renal Failure, CKD patients on Maintenance Hemodialysis fared better than AKI patients who did not
require Dialysis(mortality - 24.5% vs 35.2% respectively). Also mortality was slightly lower in CKD patients on MHD i.e.24.5% as
compared to non-RF patients i.e. 25.1%. Similarly, mortality was higher among patients with AKI who did not need HD i.e. 35.2%
when compared to non-RF patients 25.1%. Conclusion: Thus, Acute Kidney Injury (AKI) patients were at risk for more severe
disease and worst outcomes, when compared to Chronic Kidney Disease (CKD) patients on MHD. Also CKD patients on
Maintenance Hemodialysis (MHD) faired equally or better when compared to non-RF patients. Therefore Haemodialysis could
have played a protective role and needs to be explored as a novel treatment modality for SAR-COV-2 infection.
Caracterización clínica de las pacientes con aborto en el Hospital Nacional de Jalapa
Authors: Guevara Gaitán William Alexander
Published: September 2024

OBJETIVO: Describir las características clínicas de las pacientes con aborto ingresadas en el servicio de complicaciones prenatales del Hospital Nacional Nicolasa Cruz de Jalapa, durante los años 2019 al 2023. MÉTODO: Estudio descriptivo transversal con 257 pacientes. Se realizó la revisión de historiales clínicos y con una boleta de recolección de datos se documentó la información personal, antecedentes gineco obstétricos, tipo de aborto, tratamiento y antecedentes patológicos de cada paciente. Se analizaron los datos y generaron gráficas para una mejor comprensión e interpretación. RESULTADOS: De los 257 casos, el 54% de las pacientes tenían 30 años o más, el 46% escolaridad primaria, el 91% ama de casa, el 67% católica, el 76% en unión de hecho, el 82% con embarazo de primer trimestre, el tipo de aborto más frecuente con un 77% es el aborto incompleto, el 31%  de estos casos recibió terapia doble con misoprostol y legrado uterino, y el 80% no tiene antecedentes patológicos. CONCLUSIÓN: Los mayores porcentajes son mujeres mayores a 30 años, amas de casa, católicas, multíparas, con embarazo en primer trimestre que presentan aborto incompleto predominantemente y reciben tratamiento con misoprostol y legrado uterino sin antecedentes patológicos, pero eventualmente con infección urinaria y/o anemia. Es necesario que el Hospital Nacional fortalezca la vigilancia epidemiológica implementando un sistema de registro detallado de los casos de aborto, hasta su evolución al egreso para identificar tendencias, evaluar la efectividad de los tratamientos y detectar posibles áreas de mejora.
Upper Gastrointestinal Bleeding in Cardiac Patient: Etiology, Risk Factors and Management
Authors: Mghyly F. , Cherkaoui M. , Mechhor S. , Bacha H. El , Benzzoubeir N. , Errabih I.
Published: September 2024

Upper Gastrointestinal bleeding (UGIB) is a frequent emergency in hepato-gastroenterology, particularly severe in cardiac patients. The aim of this study was to investigate the etiologies, risk factors and management of upper gastrointestinal bleeding in these patients. We conducted a descriptive cross-sectional study in our department, between April 2020 and January 2024, including 56 cardiac patients who presented with UGIB and benefited from endoscopic exploration. The mean age of the patients was 69 years, with a male predominance. Of these, 46,4 % were on anticoagulants alone, 32,1% on antiplatelet agents alone, and 5,3% on a combination of the two. Gastro-duodenal ulcer was the cause of bleeding in 46.4% of patients. Blood transfusion was required in 29 patients (51,8%), and intensive care in 12 patients (21,4%). The evolution was marked by a recurrence during the same hospitalization in 10 patients (17.8%), and 3 patients (5,3%) died during the same hospitalization from hemorrhagic shock. In conclusion, cardiac patients present a higher morbidity and mortality in cases of digestive gastrointestinal bleeding, underlining the importance of rapid and effective management.
Sturge-Weber Syndrome A Case Report
Authors: Odoulou B. P. , Nzingoula C. M. , Nyamungu L. , Bouktib Y. , Hajjami A. El , Boutakioute B. , Idrissi M. Ouali , Ganouni N. Cherif Idrissi El
Published: September 2024

Sturge-Weber syndrome (SWS) or encephalo-trijeminous angiomatosis combines congenital facial angioma, leptomeningeal angioma and choroidal angioma. Diagnosis is made with MRI, ideally before ocular complications arise. In Sturge-Weber syndrome, neurodevelopmental outcome depends on recognition of the signs of severity and appropriate therapeutic management of the epilepsy. We report the case of a 9-year-old boy in whom Sturge-Weber syndrome was suspected on the basis of a facial angioma and drug-resistant epilepsy.
A INFLUÊNCIA DOS FÁRMACOS SOBRE A MICROBIOTA GASTROINTESTINAL HUMANA: UMA REVISÃO DE LITERATURA
Authors: Candido Giovanna Zuzarte , Mazarotto Edson José , Gregório Paulo Cézar , Gasparin Caroline Cardozo
Published: September 2024

A microbiota intestinal humana apresenta um papel fundamental na degradação dos alimentos e na homeostase do organismo. Idade, questões sociais, uso de medicamentos e até mesmo a dieta podem influenciar e modificar a abundância e a diversidade das bactérias que a compõe. A maioria dos medicamentos causam alterações na microbiota intestinal, resultando em aumento na abundância de alguns táxons e diminuição de outros; este fato decorre não somente de antibióticos, mas também de diversas classes, tais como: inibidores da bomba de prótons, drogas de abuso, antidepressivos, antiparkissonianos e quimioterápicos. O presente trabalho busca comparar artigos para a produção de uma revisão de literatura sobre a interação das principais classes farmacológicas com a microbiota intestinal humana. Observa-se que a microbiota intestinal se comunica com o cérebro através do eixo intestino-cérebro, influenciando o humor, a cognição e o comportamento. Sua construção se inicia no nascimento, sendo moldada pelo parto, tipo de alimentação e exposição a antibióticos, entre outros. Ao longo da vida a composição se estabiliza e com a idade avançada, pode ocorrer um desequilíbrio, favorecendo o desenvolvimento de doenças. A disbiose da microbiota intestinal pode ocasionar uma série de problemas como doenças cardiovasculares, diabetes, obesidade, doenças inflamatórias e até câncer. Além disso, é notável a existência de uma dupla influência: sua interferência sobre a resposta aos medicamentos, bem como a alteração de sua composição pelos fármacos. Antibióticos, por exemplo, podem causar disbiose, enquanto outros fármacos, como a metformina, podem ter seus efeitos modulados pela microbiota. Desta forma, a microbiota intestinal é um componente essencial da nossa saúde, influenciando diversos aspectos do nosso organismo. Compreender a relação entre a microbiota e a saúde abre caminhos para novas abordagens terapêuticas e preventivas para diversas doenças.
Incidência de Sífilis Congênita no estado de Alagoas entre os anos de 2019 a 2023.
Authors: Lícia Lins Santos  , Gabriela Melo calazans  , Rocha de Mello Gonzaga Maria Letícia , Gabriela Medeiros Nunes Santos  , Paula Thaís Cardoso Menezes  , Victor Menezes Cardoso  , Guedes Andressa de Melo Cavalcante , Trindade Thalita Marcelle Lisboa da , Melanias Fernanda Gouveia , Neri Thayná oliveira de Moraes Higashikawachi
Published: September 2024

A sífilis é um problema de saúde pública, com notificação compulsória, causado pela bactéria Treponema pallidum. É classificada como adquirida quando transmitida por contato sexual ou transfusão sanguínea, e congênita ou gestacional quando ocorre transmissão da mãe para o feto durante a gravidez. A sífilis tem alta relevância epidemiológica entre as Infecções Sexualmente Transmissíveis, devido ao impacto na saúde das gestantes e dos recém-nascidos. A alta incidência da sífilis congênita ressalta a necessidade de melhorias no pré-natal, já que a doença pode ser diagnosticada rapidamente e tratada, reduzindo as taxas de infecção fetal e os riscos associados. O objetivo principal do estudo é analisar a incidência de Sífilis Congênita no estado de Alagoas entre os anos de 2019 a 2023. Foi realizado um estudo epidemiológico analítico, utilizando como base dados coletados do Sistema de Informação de Agravos de Notificação (SINAN), onde analisou-se todos os casos de sífilis congênita notificados no estado de Alagoas durante o período de estudo de 2019 a 2023, categorizados por dados demográficos, clínicos e epidemiológicos. O estudo demonstra decaimento das taxas de Sífilis Congênita, entretanto, devido ao seu alto impacto na sociedade, com elevada morbimortalidade, continua sendo um grande problema de saúde pública.
Perfil epidemiológico de internações e óbitos por malária no brasil, entre 2013 e 2023.
Authors: Santos Bastos Alexandre Augusto , Dourado Alícia Montenegro , Leite Campos Brenda , Oliveira da Silva Jamile , Santana Bomfim Lara Brenda , Cosenza Matos Sara , Oliveira Carneiro Pedro Paulo
Published: September 2024

Introdução: A malária é uma doença infecciosa causada por um parasito do gênero Plasmodium, transmitido para humanos através da picada de fêmeas infectadas dos mosquitos do gênero Anopheles, insetos que costumam se alimentar em horários crepusculares. Objetivo: Apresentar o número de internações e óbitos por malária no Brasil no período de 2013 a 2023. Método: Estudo observacional, retrospectivo e descritivo do tipo ecológico com dados secundários obtidos no Departamento de Informática do Sistema Único de Saúde (DATASUS), e de forma mais específica, através do Sistema de Informação de Vigilância Epidemiológica da Malária (Sivep-Malária), referentes a análise os aspectos epidemiológicos da malária no Brasil. Foram incluídos todos os casos notificados no primeiro ano de sintomas de pacientes com Malária no Brasil entre os anos de 2013 e 2023. As variáveis para esse estudo foram: distribuição geográfica, faixa etária, raça, sexo, número de internações e de óbitos. Resultados: Foram identificados um total de 2.842 casos confirmados de malária em indivíduos de 20 a 39 anos, 2178 (76,6%) homens e 664 (23,4%) mulheres foram acometidos com a doença. A região Sudeste concentrou o maior número de casos o que representou um total de 1330 notificações. Somando todos os casos houve predomínio da raça Parda (44,9%). Em relação ao número de internações, a região Norte do país superou todas as outras com um total de 6700 (79,6%).  Uma maior frequência de óbitos foi notada na região Sudeste (36%) e no ano de 2021 em todas as regiões. Conclusão: A malária é uma doença mais prevalente em indivíduos brancos e pardos, homens e jovens, fatos que se traduzem em uma população economicamente produtiva. Apesar dos avanços na prevenção e tratamento, a malária ainda representa um desafio significativo para a saúde pública em muitas regiões tropicais e subtropicais, incluindo o Brasil. Principalmente nas regiões de grandes concentrações de casos e óbitos como no Sudeste do país.
Insuficiência cardíaca e os fatores relacionados à anemia ferropriva, bem como sua maior incidência em mulheres
Authors: Liliane Barbosa Jeovana , De Deus Miranda Gabriela , Volpe Eduarda , Souza Melo Samara , Alves de Sousa Matheus , Maciel de Araújo Mariana
Published: September 2024

O estudo visa elucidar se a insuficiência cardíaca e os fatores relacionados à anemia ferropriva podem estar associadas, bem como sua maior incidência em mulheres. Foi utilizada a base de dados PubMed (US National Library of Medicine), com dados científicos de 01 de agosto de 2023, com o filtro “female”, sem restrição de idioma. A deficiência de ferro (DI) apresenta índices relevantes em pacientes com insuficiência cardíaca (IC). Modificações na homeostase do ferro levam a um defeito no seu transporte e utilização, explicado pela resposta inflamatória sistêmica induzida pela IC grave , sendo mais comum no sexo feminino. Essa prevalência em mulheres está relacionada a diversos fatores como a regulação dos níveis de ferro por hormônios e resposta imunitária. A prevalência da DI aumenta com a gravidade da disfunção cardíaca, pois o ferro é essencial para reações de alta energia como a demanda muscular exige, além disso, a disfunção mitocondrial acarretada por ela causa efeitos adversos na contratilidade e relaxamento dos cardiomiócitos. A DI na IC demonstrou ser um fator que auxilia o aumento da mortalidade e pior qualidade de vida, além de ser associada ao número crescente de hospitalizações. Apesar desse fator independente contribuir para a piora da insuficiência cardíaca, em especial no sexo feminino, a suplementação intravenosa de ferro em pacientes com IC pode acarretar na melhora dos sintomas, sobressaindo os benefícios diante dos efeitos colaterais.
P.A.S.S.WORD.S (PICTURE ANALYSIS, SEQUENTIAL SCRIPTING, WORD SWAP AT WORD CRAFT): PAGHUBOG SA KASANAYAN SA PAGBUO NG SANAYSAY NG MGA MAG-AARAL SA IKA-9 NA BAITANG
Authors: Joy S. Baradillo  , Jayvee S. Bustamante  , Shellah Me T. Sedayon  , Shiela Me L. Semblante  , Marie Grace T. Varquez
Published: September 2024

Ang layunin ng pag-aaral na ito ay tukuyin ang mga epektibong estratehiya at mga interbensyon na inakma upang matugunan ang mga suliraning kinakaharap sa paggawa ng sanaysay sa Baltazar Nicor Valenzuela National High School. Ang pag-aaral na ito ay isang experimental research na gumagamit ng disenyong investigative approach na naglalayong matukoy kung may epekto ang ginamit na interbensyon sa mga suliraning kinakaharp ng mga nasa ika-9 na baitang sa paggawa ng sanaysay at masuri ang kanilang pag-unlad batay sa resulta ng pre-test at post-test. Batay sa naging resulta sa pag-aaral na ito ay may t-value na - 4.957 at p-value na <.001 na nagpapahiwatig na lubos na makabuluhan at may positibong epekto ang interbensyon o pagpapaunlad ng kasanayan ng mga mag-aaral sa pagbuo ng isang sanaysay. Ang paggamit ng interaktibo at nakakaenganyong aktibidad katulad ng P.A.S.S WORD.S o Picture Analysis, Sequencial Scripting, Word Swap at Word Craft ay nagbibigay-daan sa mga mag-aaral upang mapatibay at mapaunlad ang kakayahan ng mga mag-aaral sa paggawa ng sanaysay. Maaaring isaalang-alang ng mga tagapagturo ang paglalaan sa karagdagang atensyon sa pagpapabuti ng organisasyon, nilalaman, bokabolaryo, pamamaraan at wikang ginamit ng mga mag-aaral sa paggawa sanaysay sa pamamagitan ng iba’t-ibang interbensyon na angkop sa mga mag-aaral. Ang mga sumusunod ay idinadag: (1) Datos at pamamaraan; at (2) Mga karagdagang natuklasan.
MGA SUSING SALITA: Picture Analysis, Sequential Scripting, Word Swap, Word Craft