bluuebunny/crossref_metadata_2025 huggingface dataset:
On the Valuation of Benefits Dependent upon Promotion to a Higher Status
Authors: Thomas Ernest C.
Published: June 2019

The suggestion has been made to me by Mr. George King, to write a paper upon an interesting problem which recently occupied our joint attention.

A brief statement of the case is as follows :

In a great public service there are certain well-defined ranks, the upper ones of which are exclusively recruited by promotion from the lower ones. There are limiting ages of retirement in each rank, and in the event of an officer reaching the fixed age without being promoted he is retired on a pension. The scale of pension depends mainly on length of service, varying of course with each rank, and, as the majority enter in the lowest rank between comparatively narrow limits of age, it is sufficient to deduce an average rate of pension at each age in the various ranks. The problem is to find what amount of annual contribution, uniform throughout future service, should be made in respect of each officer now in the service, of whatever age or rank, in order to provide for the ultimate charge for pensions.

In the particular case presented there were six ranks to be dealt with, and it was understood that the calculations were to be made at 3 per-cent compound interest. I trust I may be excused for this vague statement of the case, but I could hardly be more explicit without being too definite. I shall refer to these ranks throughout as first, second, third ranks, &c., where the first is understood to mean the highest.
On the Treatment of the Depreciation in Assets Due to an Enhanced Rate of Interest
Authors: Tilt Robert Ruthven
Published: June 2019

Twenty years ago actuaries were fighting the effects of a falling rate of interest, and they did not then know that the battle would become more acute for the next few years, to be followed by a complete change of front on the side of their opponent. Life offices have, at the present time, chiefly in consequence of a rise in the rate of interest, large amounts of depreciation to face, amounts which in some cases are the equivalent of a substantial part of the quinquennial surplus. The question, therefore, of the proper treatment of this depreciation, with due regard to the enhanced rate of interest secured by the lower capital values, seems to be one that may properly occupy the attention of the Institute at a Sessional Meeting.
Canadian Mortgages Regarded as a Field for the Investment of the Funds of British Life Assurance Companies, with Some General Notes on Canadian Indebtedness
Authors: Besant Arthur Digby
Published: June 2019

In the course of the past summer I visited Canada, partly with a view to investigating upon the spot the opportunities which the Dominion might afford for mortgage investments, and partly in order to gain, at first hand, knowledge of the general financial conditions of the country.

The subject is one of great importance, and although the outbreak of war may have rendered all questions of new investments of purely academic interest for the moment, yet I hope that the following notes will be of interest to the Institute, and may be turned to some practical use in a not distant future.
Practical Points in Connection with the Formation and Valuation of Pension Funds, with a Note on Group Assurances
Authors: Burn Joseph , Symmons Frank Percy
Published: June 2019

It is with, some diffidence that we venture to submit to the Institute a paper on the subject of Pension Funds; indeed, after again perusing the masterly essays on this important subject which Mr. Manly and Mr. King have given to us it appears almost presumptuous to add anything further. Valuable papers have also been contributed by other members of our Institute. Thus Mr. James McGowan in vol. xxxvii of the Journal dealt with the subject of Pension Funds more or less generally, and supplied us with a very large number of formulæ. Mr. James Bacon in vol. xlii dealt with the construction of Salary Scales, whilst Mr. E. C. Thomas and Mr. Thomas Tinner (see J.I.A., vols. xlviii and xliv) both supplied formulæ intended to meet difficulties arising in certain events. With regard to benefit societies, Sir Alfred Watson's paper (J.I.A., vol. xliv) on this important branch of the subject may be taken as a text book.
Director's Report
Authors: Allen E. J.
Published: June 2019

After the completion of the investigation of the fauna and bottom-deposits of the outlying grounds extending from the neighbourhood of the Eddystone to Start Point, a detailed account of which was given in the last number of the Journal of the Association, a systematic investigation upon a similar plan was undertaken of the inshore grounds. The general area originally contemplated for detailed charting may be roughly described as lying between the 30-fathom line and the shore, and extending from the neighbourhood of Bolt Tail to Looe. In such an area the conditions are necessarily much more complicated than those which were met with on the Eddystone to Start grounds, where the depths varied but little from 30 fathoms, and where any effect upon the bottom fauna due to wave action was very slight. A further unfortunate complication has been introduced by the fact that immense quantities of refuse have been deposited all over the grounds immediately to the south and west of Plymouth Sound, by barges working in connection with the harbour improvement schemes in the Hamoaze and at Keyham, as well as by the barges belonging to the Plymouth Corporation, which discharge the refuse from the town. To such an extent has this deposit taken place that many of the most fruitful dredging and trawling grounds in the immediate neighbourhood have been rendered practically unworkable, and we have been compelled to abandon any serious systematic investigation of a considerable portion of the area originally contemplated.
On the Teaching of Elementaby Mathematics in Secondary Schools
Authors: Walker W. J.
Published: June 2019

In order to make this brief paper as practical as possible, I shall plunge into the subject with little introduction.

I wish to consider the question from three points of view.

(1)

What is the ideal course?

(2)

What is the best practicable course?

(3)

What effect the best practicable course should have on the teaching of the subject in our secondary schools, and also—since the two are so closely connected—in our elementary schools.
The process and delivery of CBT for depression in adults: a systematic review and network meta-analysis
Authors: López-López José A. , Davies Sarah R. , Caldwell Deborah M. , Churchill Rachel , Peters Tim J. , Tallon Deborah , Dawson Sarah , Wu Qi , Li Jinshuo , Taylor Abigail , Lewis Glyn , Kessler David S. , Wiles Nicola , Welton Nicky J.
Published: June 2019

Cognitive-behavioural therapy (CBT) is an effective treatment for depressed adults. CBT interventions are complex, as they include multiple content components and can be delivered in different ways. We compared the effectiveness of different types of therapy, different components and combinations of components and aspects of delivery used in CBT interventions for adult depression. We conducted a systematic review of randomised controlled trials in adults with a primary diagnosis of depression, which included a CBT intervention. Outcomes were pooled using a component-level network meta-analysis. Our primary analysis classified interventions according to the type of therapy and delivery mode. We also fitted more advanced models to examine the effectiveness of each content component or combination of components. We included 91 studies and found strong evidence that CBT interventions yielded a larger short-term decrease in depression scores compared to treatment-as-usual, with a standardised difference in mean change of −1.11 (95% credible interval −1.62 to −0.60) for face-to-face CBT, −1.06 (−2.05 to −0.08) for hybrid CBT, and −0.59 (−1.20 to 0.02) for multimedia CBT, whereas wait list control showed a detrimental effect of 0.72 (0.09 to 1.35). We found no evidence of specific effects of any content components or combinations of components. Technology is increasingly used in the context of CBT interventions for depression. Multimedia and hybrid CBT might be as effective as face-to-face CBT, although results need to be interpreted cautiously. The effectiveness of specific combinations of content components and delivery formats remain unclear. Wait list controls should be avoided if possible.
III. The Pahlavi Texts of Yasna LXX (Sp. LXIX), for the first time critically treated
Authors: Mills Lawrence
Published: June 2019

To those (Supreme Persons) do I sacrifice; to them do I come on for friendly aid, who are the Amešaspentas, who rule aright, who establish (all things) well; (2) and to that Chief would I take up (or ‘celebrate’ my song), to that God and ritual Chief do I sacrifice who is Auharmazd, (3) the Creator, the Rejoicer, the Producer of every benefit. (4) And I sacrifice to the Chief who is Zartušt, the Spitāmān.
II.—Certain Fundamental Power Series and their Differential Equations
Authors: Jackson F. H.
Published: June 2019

Consider a sequence of elements p1, p2, p3,.......... then (mr) will denote the sum of the first mr elements of the sequence. The simplest connection between the terms of the sequence is equality.
Cultural Understandings of Dementia in Indigenous Peoples: A Qualitative Evidence Synthesis
Authors: Jacklin Kristen , Walker Jennifer
Published: June 2019

Les démences liées à l’âge constituent un problème de santé important au Canada, en particulier chez les communautés autochtones, où les taux de démences surpassent d’environ 34 % ceux retrouvés dans la population canadienne. Cette étude présente une synthèse des données qualitatives tirées des articles traitant de la compréhension culturelle des démences chez les peuples autochtones du Canada. Les résultats principaux suggèrent que peu de recherches ont été effectuées dans ce domaine, en particulier chez les Inuits et les Métis, malgré une progression de l’exploration de ce sujet au Canada. La synthèse de la littérature a révélé que la démence est perçue comme une partie naturelle du cycle de vie par de nombreux Autochtones. Bien que les modèles communautaires et informels de soins soulèvent d’importants défis pour les aidants naturels, ils sont régulièrement appliqués. Cette synthèse sera utile pour les organismes et les prestataires de soins de santé qui recherchent des approches appropriées pour répondre aux besoins des patients et des familles autochtones aux prises avec la démence.
Rice Ecology and Ecological Relations: An Ontological Analysis of the Jiangjunya Masks and Crop Images from China's East Coast
Authors: Qu Feng
Published: June 2019

Depictions of human faces and rice-crop images found at the Jiangjunya rock-art site in Lianyungang City, Jiangsu Province, China, reveal entangling relationships between spiritual and economic aspects. Drawing on the relational ecology model and animist ontology theory, the author provides an analysis of the Jiangjunya rock art in its economic, social, spiritual and historical contexts, proposing that prehistoric farmers along China's east coast perceived rice plants as relating to persons. Rice was conceptualized not in utilitarian terms as a means of subsistence (used and consumed by humans) but rather as subjects capable of action. The human masks of Jiangjunya hence suggest a personhood for rice, rather than representing humans or anthropomorphic gods. Furthermore, the history of the Jiangjunya rock-art site corresponds with the history of local economics. The relational ontologies might have transformed gradually from human–animal interactions in the Late Palaeolithic and Early Neolithic periods to human–plant interactions in Late Neolithic societies. The author concludes that the art site was possibly treated as a mnemonic maintaining interpersonal and intersubjective relationships across thousands of years.
On the Thrust of Propellers
Authors: Chatley H.
Published: June 2019

The thrust obtainable from a propeller depends on three variable quantities :

(1)

The revolutions per second (n).

(2)

The dimensions of the propeller.

(3)

The slip (s).

Two further quantities are involved, the Torque (M) and the Power (H), but these are both dependent on the three preceding.

Assuming, in the first place, a constant slip (say, 100 per cent.), and choosing any convenient vaiue for the revolutions, we immediately fix a relation between the power consumed and the torque.
Military Aviation
Authors: Sykes F.H.
Published: June 2019

Sir John, Ladies and Gentlemen,—When, a few days ago, I had finished the notes for this evening, I rather wondered which portion of me, if any, you would kindly allow, to leave this room. You will, I am afraid, tell me it is not a lecture on Military Aviation at all, that—but I will not take the words out of your mouth. My excuse is that the words "military" and "aviation" are each so large and lead in such innumerable directions. It is difficult to obtain a correct perspective of the combination. I must rely upon the usual hope of the diffident speaker and say how desirous I am that my efforts may at all events lead to a brilliant and illuminating discussion.
Aeronautical Research in the Home
Authors: Thurston A.P.
Published: June 2019

Anyone who is worth his salt is fired with the desire to add to the sum of human knowledge. That is one of the basic principles of our lives. For all such there is a vast field of useful work in the science of Aeronautics, provided they have sufficient determination and grit. It is to these I am speaking to-night, and it is my sole purpose to endeavour to direct interest in research Work by showing how easy it is to construct simple apparatus with little money. I propose afterwards to describe a few diverse experimental researches made with such an apparatus. Needless to say, it will be a real pleasure to me to give any assistance or advice I can to all who may decide to instal such apparatus. The greater the number of experimenters at work, the faster will our knowledge proceed, and so long as the work is done it matters little whether it is you or I who do it.
A Further Three Years’ Flying Experience
Authors: Hucks B. С
Published: June 2019

Ladies and Gentlemen,—I think perhaps the title of my paper requires a short explanation before beginning.

A little over three years ago I was honoured by being asked to read a paper on Hying before this Society, which I then called, “Three Years’ Flying Experience.” I need hardly say that paper caused me no small amount of anxiety in preparing, even then, when a mere description of an ordinary flight would deeply interest most people, because when I came to get down to it I had to ask myself what there was I could find to talk about that would interest the learned and technical audience I knew I should have to face.
Observations of a Kinetic‐Scale Magnetic Hole in a Reconnection Diffusion Region
Authors: Zhong Z. H. , Zhou M. , Huang S. Y. , Tang R. X. , Deng X. H. , Pang Y. , Chen H. T.
Published: June 2019

Magnetic holes have been widely observed in various space plasma systems. The origin of magnetic holes and their influence to background plasma are under debate. In this paper, we show a kinetic‐scale electron vortex magnetic hole in a nonideal region of an active X line, which was observed by the Magnetospheric Multiscale mission at the dayside magnetopause. Intense current and nonideal electric field in the electron frame were observed within the magnetic hole, which led to a strong energy dissipation. Thus, the electron vortex magnetic hole probably provided an additional energy dissipation channel besides the electron diffusion region adjacent to the hole. We suggest that magnetic reconnection provided favorable conditions for the formation of this kinetic‐scale magnetic hole and is an important source of magnetic holes in space plasma.
How Does Radiation Code Accuracy Matter?
Authors: Huang Yi , Wang Yuwei
Published: June 2019

The accuracy of radiation calculations matters for climate simulations. Radiation code assessments typically validate such quantities as radiative fluxes and heating rates. However, it is not clear how these quantities or their uncertainties affect climate sensitivity—the extent of warming driven by the CO2 radiative forcing. Here, we assess the temperature response uncertainty by comparing simulations based on parameterized radiation codes to that based on a benchmark line‐by‐line model, in an idealized global warming (quadrupling CO2) experiment. We present an idea to quantitatively relate the radiative quantities to equilibrium temperature response. We find that when the temperature change is solely driven by the radiative process (a pure radiative adjustment), the temperature change and its uncertainty can be well diagnosed by the proposed method. Under this situation, the temperature response uncertainty is found to result from the uncertainties in both CO2 forcing and the radiative Jacobians. This calls into attention the importance of Jacobians in the radiation code intercomparison and validation. When the temperature change is driven by both radiation and convection (a radiative‐convective adjustment), the temperature change can no longer be predicted by a simple diagnostic equation. Nevertheless, the validation against the benchmark simulation provides an estimate of the temperature response errors that may be attributed to radiation code inaccuracy. We find that such errors may reach several 10th° Kelvin for surface temperature and more than 1° Kelvin for atmospheric temperatures.
Demonstrating the Impact of Colocated Behavioral Health in Pediatric Primary Care
Authors: Valleley Rachel J. , Meadows Tawnya J. , Burt Jennifer , Menousek Kathryn , Hembree Kristen , Evans Joseph , Gathje Rebecca , Kupzyk Kevin , Sevecke Jessica R. , Lancaster Blake
Published: June 2019

Objective: It is critical to address the behavioral health (BH) needs of youth given the high prevalence of diagnosable BH concerns prior to age 18 and the barriers for accessing BH services. To improve access, integration of BH services with primary care is increasing. The colocated model is one proposed method for increasing access to BH services for children. The current study sought to provide demonstration data for colocated BH services within the pediatric medical home. Method: A retrospective review of 694 new BH patient charts ranging from 1–18 years from 9 primary care clinics across three states participated. Data on number of sessions attended with a BH provider, report of homework completion (where relevant), clinician rating of adherence, and improvement ratings were collected. Results: Across all sites, 85% of referred patients attended their first appointment, and 84% of patients showed improvement over a 6-month period. Conclusions: This study is among the first to provide outcome data demonstrating the effectiveness of the colocated model for delivering BH services in primary care. Data provide information on the relationship between patient outcomes and adherence to recommendations delivered during colocated BH treatment. High attendance rates at initial appointment and overall improvement ratings were observed, suggesting the colocated BH model is a feasible model to improve access and outcomes in pediatric BH services.

Implications for Impact Statement

This study is one of the first real world applications of a colocated model of pediatric integrated primary care. The data indicate that families showed up for visits and children had improvement in behavioral health symptoms.
Seeking active RubisCOs from the currently uncultured microbial majority colonizing deep-sea hydrothermal vent environments
Authors: Böhnke Stefanie , Perner Mirjam
Published: June 2019

Almost all the inorganic carbon on Earth is converted into biomass via the Calvin–Benson–Bassham (CBB) cycle. Here, the central carboxylation reaction is catalyzed by ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO), which can be found in numerous primary producers including plants, algae, cyanobacteria, and many autotrophic bacteria. Although RubisCO possesses a crucial role in global biomass production, it is not a perfect catalyst. Therefore, research interest persists on accessing the full potential of yet unexplored RubisCOs. We recently developed an activity-based screen suited to seek active recombinant RubisCOs from the environment—independent of the native host’s culturability. Here, we applied this screen to twenty pre-selected genomic fosmid clones from six cultured proteobacteria to demonstrate that a broad range of phylogenetically distinct RubisCOs can be targeted. We then screened 12,500 metagenomic fosmid clones from six distinct hydrothermal vents and identified forty active RubisCOs. Additional sequence-based screening uncovered eight further RubisCOs, which could then also be detected by a modified version of the screen. Seven were active form III RubisCOs from yet uncultured Archaea. This indicates the potential of the activity-based screen to detect RubisCO enzymes even from organisms that would not be expected to be targeted.
Spaced training improves learning in Ts65Dn and Ube3a mouse models of intellectual disabilities
Authors: Lauterborn J. C. , Schultz M. N. , Le A. A. , Amani M. , Friedman A. E. , Leach P. T. , Gall C. M. , Lynch G. S. , Crawley J. N.
Published: June 2019

Benefits of distributed learning strategies have been extensively described in the human literature, but minimally investigated in intellectual disability syndromes. We tested the hypothesis that training trials spaced apart in time could improve learning in two distinct genetic mouse models of neurodevelopmental disorders characterized by intellectual impairments. As compared to training with massed trials, spaced training significantly improved learning in both the Ts65Dn trisomy mouse model of Down syndrome and the maternally inheritedUbe3amutant mouse model of Angelman syndrome. Spacing the training trials at 1 h intervals accelerated acquisition of three cognitive tasks by Ts65Dn mice: (1) object location memory, (2) novel object recognition, (3) water maze spatial learning. Further, (4) spaced training improved water maze spatial learning byUbe3amice. In contrast, (5) cerebellar-mediated rotarod motor learning was not improved by spaced training. Corroborations in three assays, conducted in two model systems, replicated within and across two laboratories, confirm the strength of the findings. Our results indicate strong translational relevance of a behavioral intervention strategy for improving the standard of care in treating the learning difficulties that are characteristic and clinically intractable features of many neurodevelopmental disorders.
Author Correction: Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy
Authors: Zhang Wenjia , Hu Xianglong , Shen Qi , Xing Da
Published: June 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane
Authors: Fontana Gabriele A. , Hess Daniel , Reinert Julia K. , Mattarocci Stefano , Falquet Benoît , Klein Dominique , Shore David , Thomä Nicolas H. , Rass Ulrich
Published: June 2019

Rif1 is involved in telomere homeostasis, DNA replication timing, and DNA double-strand break (DSB) repair pathway choice from yeast to human. The molecular mechanisms that enable Rif1 to fulfill its diverse roles remain to be determined. Here, we demonstrate that Rif1 is S-acylated within its conserved N-terminal domain at cysteine residues C466 and C473 by the DHHC family palmitoyl acyltransferase Pfa4. Rif1 S-acylation facilitates the accumulation of Rif1 at DSBs, the attenuation of DNA end-resection, and DSB repair by non-homologous end-joining (NHEJ). These findings identify S-acylation as a posttranslational modification regulating DNA repair. S-acylated Rif1 mounts a localized DNA-damage response proximal to the inner nuclear membrane, revealing a mechanism of compartmentalized DSB repair pathway choice by sequestration of a fatty acylated repair factor at the inner nuclear membrane.
Intensification in pastoralist cereal use coincides with the expansion of trans-regional networks in the Eurasian Steppe
Authors: Ventresca Miller Alicia R. , Makarewicz Cheryl A.
Published: June 2019

The pace of transmission of domesticated cereals, including millet from China as well as wheat and barley from southwest Asia, throughout the vast pastoralist landscapes of the Eurasian Steppe (ES) is unclear. The rich monumental record of the ES preserves abundant human remains that provide a temporally deep and spatially broad record of pastoralist dietary intake. Calibration of human δ13C and δ15N values against isotope ratios derived from co-occurring livestock distinguish pastoralist consumption of millet from the products of livestock and, in some regions, identify a considerable reliance by pastoralists on C3 crops. We suggest that the adoption of millet was initially sporadic and consumed at low intensities during the Bronze Age, with the low-level consumption of millet possibly taking place in the Minusinsk Basin perhaps as early as the late third millennium cal BC. Starting in the mid-second millennium cal BC, millet consumption intensified dramatically throughout the ES with the exception of both the Mongolian steppe where millet uptake was strongly delayed until the end of first millennium cal BC and the Trans-Urals where instead barley or wheat gained dietary prominence. The emergence of complex, trans-regional political networks likely facilitated the rapid transfer of cultivars across the steppe during the transition to the Iron Age.
Author Correction: A large-scale RNA interference screen identifies genes that regulate autophagy at different stages
Authors: Guo Sujuan , Pridham Kevin J. , Virbasius Ching-Man , He Bin , Zhang Liqing , Varmark Hanne , Green Michael R. , Sheng Zhi
Published: June 2019

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Analysis of the geometric phase for a nanowire-bridged superconducting Fabry-Perot resonator
Authors: Choi Jeong Ryeol , Ju Sanghyun
Published: June 2019

The geometric phases of a nanowire-bridged superconducting Fabry-Perot resonator subjected to a microwave transmission have been investigated through its modelling into a RLC-circuit. Because the Hamiltonian of the system is a somewhat complicated form, special mathematical techniques, such as the invariant operator method and the unitary transformation approach, have been adopted in order to treat the system; These methods are very useful for managing complicated time-dependent Hamiltonian systems. We have rigorously evaluated the analytical geometric phases in both the Fock and coherent states. Typically, the geometric phases oscillate and the amplitude of such oscillations tend to grow over time. The influence of parameters of the system on the geometric phases has been analyzed in detail through the relevant illustrations. From our research, the concept of geometric phases and associated quantum mechanical characters of the system has been clarified. Our investigation for the geometric phases is useful for understanding topological features of the system, that take place through the evolution of the wave functions.
Microbial community structure of soils in Bamenwan mangrove wetland
Authors: Liu Min , Huang Huiqin , Bao Shixiang , Tong Yuhe
Published: June 2019

Microbial community diversity and composition are important for the maintenance of mangrove ecosystem. Bacterial and archaeal community composition of the Bamenwan Mangrove Wetland soil in Hainan, China, was determined using pyrosequencing technique. Bacterial community composition presented differences among the five soil samples. Rhizobiales with higher abundance were observed in inner mangrove forest samples, while Desulfobacterales were in the seaward edge samples, and Frankiales, Gaiellales and Rhodospirillales in the landedge sample. For archaea, Crenarchaeota and Euryarchaeota dominated in five samples, but the proportion in each samples were different. Dominant archaeal community composition at the order level was similar in the seaward edge samples. The dominant archaeal clusters in the two inner mangrove forest samples were different, with Soil Crenarchaeotic Group (SCG) and Halobacteriales in sample inside of Bruguiera sexangula forest and SCG, Methanosarcinales and Marine Benthic Group B (MBGB) in sample inside of Xylocarpus mekongensis forest. The dominant archaeal clusters in land sample were unique, with Terrestrial Group and South African Gold Mine Group 1. The metabolic pathways including metabolism, genetic information processing, environmental information processing, cellular processes, organismal systems and human diseases were all detected for bacterial and archaeal functional profiles, but metabolic potentials among five samples were different.
First-principles study of the complex magnetism in Fe16N2
Authors: Bhattacharjee Satadeep , Lee Seung-Cheol
Published: June 2019

Magnetic exchange interactions in pure and vanadium (V)-doped Fe16N2 are studied within the framework of density functional theory (DFT). The Curie temperatures were obtained via both mean field approximation (MFA) and Monte Carlo (MC) calculations based on interactions that were obtained through DFT. The Curie temperature (TC) for pure Fe16N2 that was obtained under MFA is substantially larger than the experimental value, suggesting the importance of thermal fluctuations. At zero field, the calculated magnetic susceptibility shows a sharp peak at T = TC that corresponds to the presence of localized d-states. From the nature of the exchange interactions, we have determined the reason for the occurrence of the giant magnetic moment in this material, which remained a mystery for decades. Finally, we posit that Fe16N2 can also act as a satisfactory spin injector for III–V semiconductors, in addition to its application as a permanent magnet, since it has very high spin polarization (compared to elemental ferromagnets) and smaller lattice mismatch (compared to half-metallic Heusler alloys) with conventional III–V semiconductors such as GaAs and InGaAs. We demonstrate this application in the case of Fe16N2(001)/InGaAs(001) hetero-structures, which exhibit substantial spin polarization in the semiconductor (InGaAs) region. PACS number: 82.65.My, 82.20.Pm, 82.30.Lp, 82.65.Jv.
Conjunctival dysbiosis in mucosa-associated lymphoid tissue lymphoma
Authors: Asao Kazunobu , Hashida Noriyasu , Ando Satoru , Motooka Daisuke , Kurakami Hiroyuki , Nakamura Shota , Yamashita Daisuke , Maruyama Kazuichi , Kawasaki Satoshi , Yamada Tomomi , Iida Tetsuya , Nishida Kohji
Published: June 2019

To investigate the conjunctival microbiota and the association between the development of conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma and dysbiosis, DNA samples were collected from 25 conjunctival MALT lymphoma patients and 25 healthy controls. To compare the microbiota, samples were collected from the following four body locations: conjunctiva, meibomian gland, periocular skin and hand. Extracted DNA was analyzed by 16S rRNA sequences, and libraries were sequenced on an Illumina MiSeq sequencer. The differences in bacteria were characterized by using principal coordinate analysis of metagenomics data, and the differences in bacterial compositions were evaluated by linear discriminant analysis effect size. The conjunctival microbiota of MALT lymphoma patients was compositionally different from that of healthy controls. For the conjunctival MALT lymphoma patients, alterations in the microbial composition were detected, and a remarkable change was detected at the conjunctiva. Detailed analysis showed that a specific population of the microbiota, the genus Delftia, was significantly more abundant in conjunctival MALT lymphoma patients, and the genera Bacteroides and Clostridium were less abundant in the MALT lymphoma patients. A specific microbiota on the ocular surface in conjunctival MALT lymphoma patients was detected, and dysbiosis may play an important role in the pathophysiology of conjunctival MALT lymphoma.
FimH-based display of functional eukaryotic proteins on bacteria surfaces
Authors: Chmielewski Markus , Kuehle Johannes , Chrobok Danuta , Riet Nicole , Hallek Michael , Abken Hinrich
Published: June 2019

The demand for recombinant proteins for analytic and therapeutic purposes is increasing; however, most currently used bacterial production systems accumulate the recombinant proteins in the intracellular space, which requires denaturating procedures for harvesting and functional testing. We here present a novel FimH-based expression system that enables display of fully functional eukaryotic proteins while preventing technical difficulties in translocating, folding, stabilizing and isolating the displayed proteins. As examples, Gaussia Luciferase (GLuc), epidermal growth factor (EGF), transforming growth factor-α (TGF-α) and epiregulin (EPRG) were expressed as FimH fusion proteins on the surface of E. coli bacteria. The fusion proteins were functionally active and could be released from the bacterial surface by specific proteolytic cleavage into the culture supernatant allowing harvesting of the produced proteins. EGFR ligands, produced as FimH fusion proteins and released by proteolytic cleavage, bound to the EGF receptor (EGFR) on cancer cells inducing EGFR phosphorylation. In another application of the technology, GLuc-FimH expressed on the surface of bacteria was used to track tumor-infiltrating bacteria by bioluminescence imaging upon application to mice, thereby visualizing the colonization of transplanted tumors. The examples indicate that the FimH-fusion protein technology can be used in various applications that require functionally active proteins to be displayed on bacterial surfaces or released into the culture supernatant.
Synthesis and characterization of novel phenolic derivatives with the glycerol ketal group as an efficient antioxidant for gasoline stabilization
Authors: Namazifar Zeinab , Saadati Fariba , Miranbeigi Ali Akbar
Published: June 2019

The development of antioxidants containing phenol, hydroxyl, and ketal functional groups with higher thermal stability provides a creative approach to preventing the degradation of stored petroleum-derived products such as gasoline.
A chip-based potentiometric sensor for a Zika virus diagnostic using 3D surface molecular imprinting
Authors: Ricotta Vincent , Yu Yingjie , Clayton Nicholas , Chuang Ya-Chen , Wang Yantian , Mueller Steffen , Levon Kalle , Simon Marcia , Rafailovich Miriam
Published: June 2019

The high sensitivity and high selectivity demonstrated here proved that this lab-on-a-chip diagnostic has the potential to become a point-of-care (POC) detection system for rapid and accurate screening of flaviviruses.
Electrospun nanofiber supported optodes: scaling down the receptor layer thickness to nanometers – towards 2D optodes
Authors: Baranowska-Korczyc Anna , Maksymiuk Krzysztof , Michalska Agata
Published: June 2019

A novel type of optode sensor is proposed using electrospun nanofibers as the supporting inert material.
Advances in age-dating of individual uranium particles by large geometry secondary ion mass spectrometry
Authors: Szakal Christopher , Simons David S. , Fassett John D. , Fahey Albert J.
Published: June 2019

Age-dating measurements are performed on individual uranium particles that are younger, smaller, and less enriched in 235U than previously reported.
A sensitive enzyme-free lactic acid sensor based on NiO nanoparticles for practical applications
Authors: Amin Sidra , Tahira Aneela , Solangi Amber , Mazzaro Raffaello , Ibupoto Zafar Hussain , Vomiero Alberto
Published: June 2019

A facile and efficient electrochemical sensing platform has been successfully exploited for the first time for the determination of lactic acid using a nickel oxide (NiO) nanoparticle-modified glassy carbon electrode (GCE).
Development and application of a lateral flow colloidal gold immunoassay strip for the rapid quantification of ciprofloxacin in animal muscle
Authors: Yu Lu , Liu Minxuan , Wang Tianying , Wang Xianghong
Published: June 2019

Ciprofloxacin is a major metabolite of enrofloxacin.
Drastic promotion of guanine oxidation via electron transfer in Ψ-type DNA
Authors: Sakurai Shunsuke , Esumi Mayu , Tanaka Makiko
Published: June 2019

Drastic promotion of guanine oxidation was induced by not only intraduplex ET but also interduplex ET in Ψ-type DNA in a crowded environment using PEG.
Unexpected reaction patterns enable simultaneous differentiation of H2S, H2Sn and biothiols
Authors: Chen Wenqiang , Fu Li , Chen Chunfei , Xiao Junan , Li Wenxiu , Zhang Liangliang , Xiao Qi , Huang Chusheng , Sheng Jiarong , Song Xiangzhi
Published: June 2019

A robust fluorescent probe, MCP1, was developed for triple-detection of H2S, H2Sn and biothiols for the first time.
Transparent crystalline cubic SiC-on-glass electrodes enable simultaneous electrochemistry and optical microscopy
Authors: Phan Hoang-Phuong , Masud Mostafa Kamal , Vadivelu Raja Kumar , Dinh Toan , Nguyen Tuan-Khoa , Ngo Kieu , Dao Dzung Viet , Shiddiky Muhammad J. A. , Hossain Md Shahriar A. , Yamauchi Yusuke , Nguyen Nam-Trung
Published: June 2019

This work introduces transparent SiC-on-glass as a new platform for biosensing applications which enables cell culturing, stimulating, microscopy-imaging and bioelectrochemical detection.
Rhodium(iii)-catalysed carboxylate-directed C–H functionalizations of isoxazoles with alkynes
Authors: Yugandar Somaraju , Nakamura Hiroyuki
Published: June 2019

Isoxazolyl-4-carboxylic acids underwent rhodium(iii)-catalysed carboxylate-directed C–H functionalizations with internal alkynes to produce pyranoisoxazolones, isoquinolines, and 5-alkenylisoxazoles controlled by oxidants.
Traceable in-cell synthesis and cytoplasm-to-nucleus translocation of a zinc Schiff base complex as a simple and economical anticancer strategy
Authors: Cao Qian , Yang Jing , Zhang Hang , Hao Liang , Yang Gang-Gang , Ji Liang-Nian , Mao Zong-Wan
Published: June 2019

A facile and cheap strategy based on visualized in-cell synthesis of theranostic Zn Schiff base complexes realizes cancer-specific therapy.
Inversion of donor–acceptor roles in photoinduced intervalence charge transfers
Authors: Aramburu-Trošelj Bruno M. , Oviedo Paola S. , Ramírez-Wierzbicki Ivana , Baraldo Luis M. , Cadranel Alejandro
Published: June 2019

Upon MLCT photoexcitation, {(tpy)Ru} becomes the electron acceptor in the mixed valence {(tpy˙−)RuIII−δ-NC-MII+δ} moiety, reversing its role as the electron donor in the ground-state mixed valence analogue.
Rapid NMR assignments of intrinsically disordered proteins using two-dimensional13C-detection based experiments
Authors: Sukumaran Sujeesh , Malik Shahid A. , R. Shankararama Sharma , Chandra Kousik , Atreya Hanudatta S.
Published: June 2019

An approach for rapid resonance assignments in proteins based on 2D13C-detected NMR experiments combined with amino acid selective unlabeling.
Lithium–oxygen batteries with triplex Li+-selective solid membranes
Authors: Choi Youngbin , Jung Keeyoung , Kim Hyeong-Jun , Moon Ji-Woong , Lee Jong-Won
Published: June 2019

A lithium–oxygen battery based on a Li+-selective solid membrane (LSSM) with a triplex (porous/dense/porous) structure is proposed.
Sub-nanometer scale size-control of iron oxide nanoparticles with drying time of iron oleate
Authors: Balakrishnan Thiruparasakthi , Lee Min-Jae , Dey Jahar , Choi Sung-Min
Published: June 2019

The drying time of iron oleate as a single and reliable control parameter for the fine size control (with a sub-nanometer scale step) of monodisperse IONPs in the large-scale thermal decomposition method.
Role of conformation in crystal formation and transition of polybutene-1
Authors: Qiu Xing , Hu Cunliang , Li Jingqing , Huang Dinghai , Jiang Shichun
Published: June 2019

Polymer conformation is the molecular basis underlying essentially all physical properties of polymers, and chain conformation and conformational energy play central roles in crystalline structure formations and structure transitions of polymers.
Vibrational spectra of Pb2Bi2Te3, PbBi2Te4, and PbBi4Te7 topological insulators: temperature-dependent Raman and theoretical insights from DFT simulations
Authors: Mal Priyanath , Bera G. , Turpu G. R. , Srivastava Sunil K. , Gangan A. , Chakraborty Brahmananda , Das Bipul , Das Pradip
Published: June 2019

Insertion of lead and lead telluride in Bi2Te3 leads to a change in the thermal conductivity, frequency shift, and the broadening of phonon modes.
Effects of complexation with sulfuric acid on the photodissociation of protonated Cinchona alkaloids in the gas phase
Authors: Ben Nasr Feriel , Alata Ivan , Scuderi Debora , Lepère Valeria , Brenner Valerie , Jaïdane Nejm-Eddine , Zehnacker Anne
Published: June 2019

The complex formed between Cinchona alkaloids and sulphuric acid consists of a doubly protonated Cinchona alkaloid strongly bound to a bisulphate HSO4− anion. This structure explains the lack of photo-reactivity of the complex upon UV irradiation.
Localised contacts lead to nanosecond hinge motions in dimeric bovine serum albumin
Authors: Ameseder Felix , Biehl Ralf , Holderer Olaf , Richter Dieter , Stadler Andreas M.
Published: June 2019

Domain motions in proteins are crucial for biological function.
Structural correlations tailor conductive properties in polymerized ionic liquids
Authors: Doughty Benjamin , Genix Anne-Caroline , Popov Ivan , Li Bingrui , Zhao Sheng , Saito Tomonori , Lutterman Daniel A. , Sacci Robert L. , Sumpter Bobby G. , Wojnarowska Zaneta , Bocharova Vera
Published: June 2019

In this paper, it was demonstrated that the mobile ion (anion) size and pendant group chemistry affect the packing of the polymer chains and influence conductivity in imidazolium based PolyILs.
Ultrathin metal/covalent–organic framework membranes towards ultimate separation
Authors: Zhang Chao , Wu Bai-Heng , Ma Meng-Qi , Wang Zuankai , Xu Zhi-Kang
Published: June 2019

Ultrathin metal/covalent–organic framework (MOF/COF) membranes have attracted increasing research interest and have been considered as state-of-the-art platforms applied in various environment- and energy-related separation/transportation processes.
A mechanochemical route for the synthesis of VNbO5 and its structural re-investigation using structure solution from powder diffraction data
Authors: Valentoni Antonio , Barra Paolo , Senes Nina , Mulas Gabriele , Pistidda Claudio , Bednarcik Jozef , Torre Francesco , Garroni Sebastiano , Enzo Stefano
Published: June 2019

VNbO5 with a revised space group P212121 versus Pnma has been successfully synthesized by a solvent-free mechanochemical route.
Preparation, characterization and electrocatalysis performance of a trimeric ruthenium-substituted isopolytungstate
Authors: Wan Rong , Li Huafeng , Ma Xinyi , Liu Zhen , Singh Vikram , Ma Pengtao , Zhang Chao , Niu Jingyang , Wang Jingping
Published: June 2019

The ruthenium-containing isopolytungstate Rb10K3H6[SeO3(H9Ru5.5W30.5O114)]Cl3·48H2O was isolated and then served as a catalyst, showing electrochemical catalytic activity towards the oxidation reaction of nitrite.
A mixed-spin spin-crossover thiozolylimine [Fe4L6]8+ cage
Authors: Li Li , Craze Alexander R. , Mustonen Outi , Zenno Hikaru , Whittaker Jacob J. , Hayami Shinya , Lindoy Leonard F. , Marjo Christopher E. , Clegg Jack K. , Aldrich-Wright Janice R. , Li Feng
Published: June 2019

A mixed-spin spin-crossover thiozolylimine [Fe4L6]8+ tetrahedral cage is reported.
Hyperstable chromium(iii)/manganese(ii) bimetallic wheel clusters with visible photoactivity
Authors: Zhang Junxiang , Zhang Jian , Liu Xuguang , Xu Tingting , Liu Shengjun , Hou Xudong , Tong Jing , Wang Yan , Wang Yang , Albolkany Mohamed K. , Liu Bo
Published: June 2019

Carboxylate-coordination and transition metal-doping into nanocluster lead to a hyperstable and photo-active hetero-polyoxotitanate of [Cr8−xMnx(OH)8−x(H2O)x(OOCC6H5)16,x= 1.11] with visible light photocurrent and photocatalytic H2evolution rate.
Revealing the reduction process of Cu(ii) by sodium bis(trimethylsilyl)amide
Authors: Yang Dali , Yi Hong , Chen Hong , Qi Xiaotian , Lan Yu , Pao Chih-Wen , Lee Jyh-Fu , Zhang Heng , Chen Yi-Hung , Lei Aiwen
Published: June 2019

Using XAS and EPR spectroscopy, we showed that sodium bis(trimethylsilyl)amide (NaHMDS) serving as an electron donor could reduce Cu(ii) to an active Cu(i) species.
Combined mild chemical pretreatments for complete cadmium release and cellulosic ethanol co-production distinctive in wheat mutant straw
Authors: Cheng Liangliang , Wang Lingqiang , Wei Luyao , Wu Yue , Alam Aftab , Xu Chengbao , Wang Yanting , Tu Yuanyuan , Peng Liangcai , Xia Tao
Published: June 2019

A complete cadmium release and high cellulosic ethanol co-production was achieved in wheat mutant straw in two-step mild chemical pretreatment.
An improved in situ technique for the analysis of the Os isotope ratio in sulfides using laser ablation-multiple ion counter inductively coupled plasma mass spectrometry
Authors: Zhu Lü-Yun , Liu Yong-Sheng , Jiang Shao-Yong , Lin Jie
Published: June 2019

The 187Os/188Os ratio in low-Os sulfides could be in situ measured precisely by LA-MC-ICP-MS equipping an array of ion counters.
Synthesis, characterization and computational study of an ilmenite-structured Ni3Mn3Ti6O18thin film photoanode for solar water splitting
Authors: Munawar Khadija , Perveen Fouzia , Shahid Muhammad Mehmood , Basirun Wan Jeffrey , Bin Misran Misni , Mazhar Muhammad
Published: June 2019

Thin films of a Ni3Mn3Ti6O18solid solution photoanode have been deposited on an FTO coated glass substrate and experimental results are supported by DFT studies.
Tracking pereirine and flavopereirine in pau-pereira using Raman and SERS spectroscopies
Authors: Maia Lenize F. , Almeida Márcia R. , Carvalho Dhieniffer F. , Rosa Nathália M. P. , Sant’Ana Antonio Carlos , Costa Luiz Antônio S. , de Oliveira Vanessa End , Pinto Angelo C. , de Oliveira Luiz Fernando C.
Published: June 2019

Raman and SERS spectroscopies have been used to identify the bioactive compounds pereirine and flavopereirine from stem bark, ethanolic crude extracts and infusions.
A putative heme manganese(v)-oxo species in the C–H activation and epoxidation reactions in an aqueous buffer
Authors: Harmalkar Dinesh S. , Santosh G. , Shetgaonkar Siddhi B. , Sankaralingam Muniyandi , Dhuri Sunder N.
Published: June 2019

Synthesis and reactivity studies of manganese(v)-oxo species in the C–H activation of alkyl hydrocarbons and epoxidation of cyclohexene in aqueous conditions are investigated.
New thiosemicarbazide and dithiocarbazate based oxidovanadium(iv) and dioxidovanadium(v) complexes. Reactivity and catalytic potential
Authors: Maurya Mannar R. , Sarkar Bithika , Kumar Amit , Ribeiro Nádia , Miliute Aistè , Pessoa João Costa
Published: June 2019

The new thiosemicarbazide and dithiocarbazate based vanadium complexes show remarkable catalytic potential for oxidation of alcohols and simple arenes.
In vitroexperiments and infrared spectroscopy analysis of acid and alkaline phosphatase inhibition by vanadium complexes
Authors: Parente Juliana E. , Naso Luciana G. , Jori Khalil , Franca Carlos A. , da Costa Ferreira Ana Maria , Williams Patricia A. M. , Ferrer Evelina G.
Published: June 2019

Two oxidovanadium complexes with 4-aminobenzoic acid and/or the peroxo anion as ligands were synthesized and characterized by elemental analysis, conductivity measurements, TGA/DTA,1H NMR, EPR, FTIR, and UV/vis spectroscopies.
Post-synthetic modification of a Tb-based metal–organic framework for highly selective and sensitive detection of metal ions in aqueous solution
Authors: Huangfu Mengjie , Tian Xueqin , Zhao Shuang , Wu Pengyan , Chu Huacong , Zheng Xiaotian , Tang Jiawei , Wang Jian
Published: June 2019

Post-synthetic modification of a MOF led to selectivity and sensitivity enhancement for Fe3+detection in water with a detection limit of 70 nM.