bluuebunny/crossref_metadata_2025 huggingface dataset:
Administrative Traditions: Concepts and Variables
Authors: Peters B. Guy
Published: December 2021

Contemporary administrative systems are shaped in part by their past and by the conceptions of good administration that are embedded in administrative culture. Administrative traditions shape contemporary administration in Europe and have been heavily influenced by European models. Administrative tradition means an historically based set of values, structures, and relationships with other institutions that define the nature of appropriate public administration. Seven dimensions can be used to both define these traditions and categorize public administration into four groups of nations. This explanation is similar to cultural explanations, but it includes the influence of structures as well as ideas. While the model of traditions developed is based largely on European and North American experiences, it can also be applied to a much broader range of administrative systems.
Key Actors in the Management of Crises: International and Regional Organizations
Authors: Gardell Eva-Karin , Verbeek Bertjan
Published: December 2021

In crisis-ridden times, when events like the COVID-19 pandemic, acts of terrorism, and climate change-induced crises are making constant headlines, states, businesses, and individuals alike look to international organizations (IOs) to help them weather the storm. How can the role of IOs be better understood in the context of crisis and crisis management? For a start, it requires a distinction between objective and subjective crisis perspectives in studying IOs. From an objective perspective, IOs are examined as unitary actors that have the aim of contributing to the stability of the international political system. On the other hand, in a subjectivistic approach, IOs’ actual crisis management is the focus. In this perspective, the emphasis is on an IO’s internal life, that is, its perceptions, bureau politics, and decision-making. In the exploration of these issues, IOs can no longer by studied as entities but have to be unwrapped into small groups and individuals, such as members of secretariats or member state’s top politicians. As borne out by theories developed by scholars of crisis management and foreign-policy analysis, centralization and cognitive bias are of special interest in the study of IOs. IOs’ crisis management has four crisis phases and tasks: sense-making, decision-making, meaning-making, and crisis termination. Finally, crises may prove a threat to, or an opportunity for, IOs. Transnational crises may usher in IOs’ foundation and flourishing, or they may contribute to IOs’ demise.
Germany: An Army in a Democracy in an Epoch of Extremes
Authors: Abenheim Donald , Halladay Carolyn
Published: December 2021

The German soldier and German politics in the second decade of the 21st century face the challenges of a deteriorating international system as well as the reappearance of integral nationalism at home and abroad. The security-building roles and missions of the German armed forces in the three decades since unity are being reoriented to alliance collective defense as well as security building amid great friction with sources near and far. These phenomena in their variety threaten the civic and multilateral tenets of German statecraft as well as fundamental military standards and defense organization since 1949, and in particular, since unification in 1990. Specifically, the constants of postwar German democratic civil–military relations—the citizen in uniform, both bound and empowered by Innere Führung, serving in arms in a force firmly located in European and alliance structures but with a low profile at home, undergirded by both legal and social preferences—have had to withstand multiple blows of late. Some of these blows have been a result of unintended consequences of various policies or nonpolicies articulated without sufficient regard for current context; some as a result of unforced errors by leaders relying on outdated assumptions; and some as intentional provocations amid a fraying political consensus. While the German defense establishment—civilian and uniformed—has thus far mostly mastered these circumstances, the strain on German democratic civil–military relations is unmistakable. Thus, Germany’s civil–military relations face the test that they have well surmounted in the past, that is, to have a good democracy and a good army at the same time. The Bundeswehr’s 2020 deployment amid the coronavirus crisis, alongside discussions about a corona dividend in times of exploding state deficits, seems to have boosted soldiers’ popularity, and thus has opened a new facet of civil–military relations. However, the Bundeswehr must be careful not to foster a self-image of camouflaged civilian service or to create an identity crisis of its Afghanistan veterans serving for months as attendants in retirement homes. The public debate and official reflection manifest at best a mediocre comprehension of the needs of the soldier and the imperative to find a usable past for soldiers asked to defend democracy against its many enemies, without falling prey to militarism and integral nationalism. Innere Führung remains the valid heritage of the German soldier, even—or perhaps especially—for those who are asked by duty and fate to risk their lives in combat.
Music Performance
Authors: Pfordresher Peter
Published: December 2021

Music performance involves precise motor control that is coordinated with higher order planning to convey complex structural information. In addition, music performance usually involves motor tasks that are not learned spontaneously (as in the use of the vocal apparatus), the reproduction of preestablished sequences (notated or from memory), and synchronized joint performance with one or more other musicians. Music performance also relies on a rich repertoire of musical knowledge that can be used for purposes of expressive variation and improvisation. As such, the study of music performance provides a way to explore learning, motor control, memory, and interpersonal coordination in the context of a real-world behavior. Music performance skills vary considerably in the population and reflect interactions between genetic predispositions and the effect of intensive practice. At the same time, research suggests that most individuals have the capacity to perform music through singing or learning an instrument, and in this sense music performance taps into a universal human propensity for communication and coordination with conspecifics.
Informal Economies
Authors: Aryeetey Ernest
Published: December 2021

The expressions, “informal economy,” “informal sector,” and “informal employment” reflect statistical terms and definitions used to describe various aspects of informality. They are the result of several decades of work to develop a framework that adequately represents the multifaceted nature of informality as it applies not only to developing countries, but also to other transition and developed economies. The informal sector is generally viewed as the set of activities of small unregistered enterprises, while informal employment refers to employment within the formal or informal sector that lacks any form of protection, whether legal or social.1 The informal economy is a broader concept that encompasses all of these elements in their different forms, including their outputs and outcomes.

The many different views about the drivers and composition of the informal economy in Africa have influenced various prescriptions and policy responses. On the one hand, some have viewed informality as being inimical to investment and growth, given that the activities undertaken usually fall outside of official regulation and control. The policy response has, therefore, often been to clamp down on or formalize the activities and relationships within the informal economy. On the other hand, informality is sometimes viewed as critical for growth and poverty reduction, given that the informal economy is inextricably linked to the formal economy while also serving as an important source of livelihood for millions of people. As a result of this, some effort has recently gone into providing a more supportive environment to enhance productivity within the informal economy and minimize its inherent vulnerabilities in the last decade.

In the face of increasing globalization and access to new technologies that will drive the future of work, there is concern about the future of informal economic activities. Whether new technologies lead to a decline or upscaling of the informal economy in Africa will depend on several elements. Technology will not only shape how informality in Africa is viewed, but will influence the kind of activities undertaken, its links with the formal economy, and ultimately, the public policy response, which will itself be shaped by advances in technology.
The Macroeconomics of Stratification
Authors: Seguino Stephanie
Published: December 2021

Stratification economics, which has emerged as a new subfield of research on inequality, is distinguished by a system-level analysis. It explores the role of power in influencing the processes and institutions that produce hierarchical economic and social orderings based on ascriptive characteristics. Macroeconomic factors play a role in buttressing stratification, especially by race and gender. Among the macroeconomic policy levers that produce and perpetuate intergroup inequality are monetary policy, fiscal expenditures, exchange rate policy, industrial policy, and trade, investment, and financial policies. These policies interact with a stratification “infrastructure,” comprised of racial and gender ideologies, norms, and stereotypes that are internalized at the individual level and act as a “stealth” factor in reproducing hierarchies. In stratified societies, racial and gender norms and stereotypes act to justify various forms of exclusion from prized economic assets such as good jobs. For example, gendered and racial stereotypes contribute to job segregation, with subordinated groups largely sequestered in the secondary labor market where wages are low and jobs are insecure. The net effect is that subordinated groups serve as shock absorbers that insulate members of the dominant group from the impact of negative macroeconomic phenomena such as unemployment and economic volatility. Further, racial and gender inequality have economy-wide effects, and play a role in determining the rate of economic growth and overall performance of an economy. The impact of intergroup inequality on macro-level outcomes depends on a country’s economic structure. While under some conditions, intergroup inequality acts as a stimulus to economic growth, under other conditions, it undermines societal well-being. Countries are not locked into a path whereby inequality has a positive or negative effect on growth. Rather, through their policy decisions, countries can choose the low road (stratification) or the high road (intergroup inequality). Thus, even if intergroup inequality has been a stimulus to growth in the past, it is possible to choose an equity-led growth path.
The Implications of Informal Settlement Upgrading Programs for Access to Water, Sanitation, and Public Health
Authors: Satterthwaite David , Sverdlik Alice
Published: December 2021

Most cities in low- and middle-income countries have substantial proportions of their population living in informal settlements—sometimes up to 60% or more. These also house much of the city’s low-income workforce; many informal settlements also concentrate informal economic activities. These settlements usually lack good provision for water, sanitation, and other essential services.

The conventional government responses were to bulldoze them or ignore them. But from the 1960s, another approach became common—upgrading settlements to provide missing infrastructure (e.g., water pipes, sewers, drains). In the last 20 years, community-driven upgrading has become increasingly common. Upgrading initiatives are very diverse. At their best, they produce high-quality and healthy living conditions and services that would be expected to greatly reduce illness, injury or disablement, and premature death. But at their worst, upgrading schemes provide a limited range of improvements do nothing to reduce the inhabitants’ exclusion from public services.

There is surprisingly little research on upgrading’s impact on health. One reason is the very large number of health determinants at play. Another is the lack of data on informal settlement populations.

Much of the innovation in upgrading is in partnerships between local governments and organizations formed by informal settlement residents, including slum/shack dweller federations that are active in over 30 nations.

Community-driven processes can deal with issues that are more difficult for professionals to resolve—including mapping and enumerations. Meanwhile, local government can provide the connections to all-weather roads, water mains, sewers, and storm drains into which communities can connect.
Epigenetics and Applied Anthropology
Authors: Klein Charles H.
Published: December 2021

Since Francis Crick and James D. Watson’s discovery of DNA in 1953, researchers, policymakers, and the general public have sought to understand the ways in which genetics shapes human lives. A milestone in these efforts was the completion of the Human Genome Project’s (HGP) sequencing of Homo sapiens’ nearly three million base pairs in 2003. Yet, despite the excitement surrounding the HGP and the discovery of the structural genetic underpinnings of several debilitating diseases, the vast majority of human health outcomes have not been linked to a single gene. Moreover, even when genes have been associated with particular diseases (e.g., breast and colon cancer), it is not well understood why certain genetically predisposed individuals become ill and others do not. Nor has the HGP’s map provided sufficient information to understand the actual functioning of the human genetic code, including the role of noncoding DNA (“junk DNA”) in regulating molecular genetic processes.

In response, a growing number of scientists have shifted their attention from structural genetics to epigenetics, the study of how genes express themselves in particular situations and environments. Anthropologists play roles in these applications of epigenetics to real-world settings. Their new theoretical frameworks unsettle the nature-versus-nurture binary and support biocultural anthropological research demonstrating how race becomes biology and embodies social inequalities and health disparities across generations. Ethnographically grounded case studies further highlight the diverse epigenetic logics held by healthcare providers, researchers, and patient communities and how these translations of scientific knowledge shape medical practice and basic research. The growing field of environmental epigenetics also offers a wide range of options for students and practitioners interested in applying the anthropological toolkit in epigenetics-related work.
Black Nationalism
Authors: Newman Mark
Published: December 2021

The popular media often illustrate black nationalism with images of Malcolm X and black leather-jacketed, Afro-wearing, armed Black Panthers in the 1960s, and, in later decades, Louis Farrakhan and hip-hop artists such as Public Enemy. Although historians disagree about black nationalism’s composition and origins, they argue that it has a long pedigree in American history, traceable at least to the first half of the 19th century, if not earlier. While men were most often black nationalism’s public exponents, and some emphasized manhood and female subordination, black nationalism also appealed to many black women, some of whom also exercised leadership and organizational skills in its service. Marcus Garvey, a Jamaican, led the first mass black nationalist organization in the United States, the Universal Negro Improvement Association (UNIA), during the 1920s. Like 19th-century black nationalists, Garvey advocated an independent state for people of African descent, black uplift, and the “civilizing” of Africa. Although not original to him, his emphasis on the right to self-defense, independent black economic development, and pride in African history boosted the UNIA’s popularity. Garvey fell victim to state oppression in the United States, but some former Garveyites joined the Moorish Science Temple of America (MSTA) and probably also the Nation of Islam (NOI), both of which rejected Christianity, identified blacks as Asiatics, and adopted particularist interpretations of Islam.

In the 1950s and 1960s, Malcolm X, the charismatic son of Garveyite parents, became the Nation’s chief recruiter. Personal differences with Elijah Muhammad, the Nation’s leader since the 1930s, eventually led to Malcolm X’s departure in 1964. Although he was assassinated in 1965, Malcolm X’s calls for armed self-defense, self-determination and black pride, and identification with anticolonial struggles heavily influenced Black Power advocates. Some civil rights organizations and workers, who were disillusioned by intransigent white racism and distrustful of white liberals, championed Black Power, which was multifaceted and sometimes more reformist than nationalist. In the early 1990s, polls suggested that black nationalist ideas were more popular than during their supposed heyday in the late 1960s, before internal dissension and state repression undermined many Black Power groups.
Jimmy Carter and Human Rights in Latin America
Authors: Walker Vanessa
Published: December 2021

Human rights was perhaps the defining feature of Jimmy Carter’s presidency. Although much attention was given at the time to its impact on US relations with the Soviet Union and Eastern Europe, Latin America was equally, if not more, important in defining and implementing Carter’s vision of a human rights foreign policy. Latin America was the site of some of the Carter administration’s most visible and concentrated human rights diplomacy, and revealed the central logic and persistent challenges of implementing a coherent, comprehensive human rights policy that worked in tandem with other US interests. Carter’s Latin America policy reimagined US national interests and paired human rights with greater respect for national sovereignty, challenging US patterns of intervention and alignment with right-wing anticommunist dictatorships throughout the Cold War. In the Southern Cone, the Carter administration’s efforts to distance the United States from repressive Cold War allies and foster improvements in human rights conditions provoked nationalist backlash from the military regimes, and faced domestic criticism about the economic and security costs of new human rights policies. Similarly, in Central America, the administration faced the challenge of reforming relations with abusive anticommunist allies in Nicaragua, Guatemala, and El Salvador without supporting communist revolution. Its tepid and cautious response to violence by the Central American governments called into question the Carter administration’s commitment to its human rights agenda. In Cuba, the Carter administration sought to advance human rights as part of a larger effort to normalize relations between the two countries, an effort that was ultimately stymied by both geopolitical dynamics and domestic politics. Although limited in the fundamental changes it could coax from foreign governments and societies, the administration’s policy had a tangible impact in specific high-profile human rights cases. In the long term, it helped legitimize human rights as part of international diplomacy in Latin America and beyond, amplifying the work of other government and nongovernment proponents of human rights.
Black Tribute in the Spanish Americas
Authors: Gharala Norah
Published: December 2021

From the late 16th to the early 19th centuries, free individuals, families, and corporate groups whose reputations or self-descriptions defined them as Black in the Spanish Americas were subject to a specific tax. The royal tribute tax established the relationship between loyal vassals and a responsive Crown. Under Habsburg rule, tribute circumscribed the freedom of Black subjects but offered a path to privileges for those who provided services to the Crown. Attempts to levy the tax in the 16th and 17th centuries were wide-ranging but yielded comparatively small amounts of revenue. Tribute, nevertheless, affected many regions of the Spanish Americas, either by its collection or via the strategies Black people took to avoid it or contest its imposition. The responses of Black people and local officials to the tax determined how regularly it was enforced and how much revenue it would generate. Even where it failed, debates over tribute and attempts to collect it can reveal what it meant to be Black for colonial officials and ordinary people. Bourbon reforms led to an increasing emphasis on the fiscal potential of Black tribute, much of which became concentrated in the heart of New Spain. Hundreds of thousands of people not only paid tribute but were registered using new methods. The information produced within the tribute regime approximated the density, distribution, and interconnectedness of Black and Indian populations. In addition to the revenue and data its collection yielded, the imposition of Black tribute remains fundamental to understanding the colonial status, sense of identity, and experiences of Black people in the Spanish Empire.
Witchcraft in Colonial Latin America
Authors: von Germeten Nicole
Published: December 2021

The European ideas associated with witchcraft came to the Americas as a multipronged weapon of imperialism, a conception of non-Christian beliefs not as separate worldviews but as manifestations of evil and the reigning power of the devil over Indigenous peoples and, slightly later, African slaves and free people of African origins or heritage. To create this imperialist concept, colonizers drew from a late medieval demonological literature that defined witchcraft as ways of influencing one’s fate through a pact with the devil and the ritual of witches’ sabbaths. Through the court structure of the Holy Offices of the Spanish and Portuguese Inquisitions, Iberian imperialists set up judicial processes that they designed to elicit confessions from their colonial subjects regarding their involvement in what was labeled witchcraft and witches’ sabbaths, but which was most likely either non-European beliefs and practices, or even popular European ideas of healing. Archival documents from the Holy Office fueled Europeans’ vision of themselves as on the side of cosmic good as well as providing some details regarding popular practices such as divination and love magic. Whatever ethnographic details emerge from this documentation, the use of the terminology of witchcraft always signals an imperialistic lens.
The Institute of Geology of Mexico and Its Precedents: History and Legacy
Authors: Morelos Rodríguez Lucero
Published: December 2021

In 2019, the Institute of Geology celebrated its ninetieth anniversary as part of Universidad Nacional Autónoma de México (UNAM). The main establishment in Mexico for the teaching, research, and dissemination of the geological sciences, it is an institution with a long history and a great scientific legacy. It dates back to the 19th century, since it is the heir to the Geological Institute of Mexico (1888), the first institute in the Mexican republic to carry out research in the geological sciences and to study the country’s territory from three points of view: scientific, technical, and industrial. It was conceived by the mining engineer Antonio del Castillo (1820–1895) to meet the need to scientifically explore the country’s latent mineral wealth, for which reason its functions included: mapping regions whose lithology and resources were unknown, providing specialized services to the public—the analysis and classification of water, rocks, land, fossils, minerals, and oil—and creating a geological and paleontological museum for the nation.

From 1888 to 1917, the institution was part of the Ministry of Development, Colonization, Industry, and Commerce (Ministerio de Fomento, Colonización, Industria y Comercio). In 1917, the Venustiano Carranza administration promulgated a new constitution, reformed governmental administration, and created the Ministry of Industry, Commerce, and Labor (Secretaría de Industria, Comercio y Trabajo), which was responsible for all questions related to industries such as mining and oil. Although it lapsed somewhat between 1917 and 1929, during the armed conflict of the Mexican Revolution (1910–1920), the Institute of Geology of Mexico was assigned to the Department of Geological Studies and Explorations, with the task of carrying out applied science through the study of new and old mining areas and the location of aquifers.

A new scenario emerged in 1929 when the administration of President Emilio Portes Gil enacted the Organic Law of the National University, granting the latter university autonomy, which also allowed institutions of a scientific nature such as the National Astronomical Observatory, the National Library, the Department of Biological Studies, and the National Geological Institute to carry out research as one of their substantive activities. On November 16, 1929, the former Department of Geological Studies and Explorations was incorporated in the most important scholarly institution of Mexico under the name of the Institute of Geology.
The Charro as a Humorous Rural Stereotype in Mexico in the 1920s
Authors: Navarro Granados Daniel Efraín
Published: December 2021

At the beginning of the 20th century, the charro, a traditional figure from the rural world, emerged on the Mexican cultural scene as a relevant stereotype. In the following years, the charro transformed into a national personification of Mexico, especially once it became a key figure of Mexican cinema and mariachi music. Notwithstanding this fact, its trajectory was more convoluted than it seems, and different versions of the character coexisted at least until the 1920s. Whereas the charro was usually represented as an attractive and seductive man, there was also a comic version, portrayed as an overweight or unkempt man with a provincial mentality. The characters played by the comic performer Leopoldo Beristáin and the protagonists of Sunday comic strips, such as Don Catarino and Mamerto Albondiguilla, were some examples of the latter. While the positive interpretation of the charro ended up prevailing as the main iteration of the character, the comic depictions of this stereotype show the rejection and contempt that the urban population felt for a rural world that had invaded the Mexican capital as a result of the revolution—a world perceived as provincial, backward, and laughable, an idea that would dominate foreign and national imageries of Mexico.
The Strait of Magellan—a Gateway to New Worlds
Authors: Onetto Pavez Mauricio
Published: December 2021

The year 2020 marks the five hundredth anniversary of the “discovery” of the Strait of Magellan. The unveiling of this passage between 1519 and 1522 allowed the planet to be circumnavigated for the first time in the history of humanity. All maritime routes could now be connected, and the idea of the Earth, in its geographical, cosmographic, and philosophical dimensions, gained its definitive meaning. This discovery can be considered one of the founding events of the modern world and of the process of globalization that still continues today.

This new connectivity awoke an immediate interest in Europe that led to the emergence of a political consciousness of possession, domination, and territorial occupation generalized on a global scale, and the American continent was the starting point for this. This consciousness also inspired a desire for knowledge about this new form of inhabiting the world. Various fields of knowledge were redefined thanks to the new spaces and measurements produced by the discovery of the southern part of the Americas, which was recorded in books on cosmography, natural history, cartography, and manuscripts, circulating mainly between the Americas and Europe.

All these processes transformed the Strait of Magellan into a geopolitical space coveted by Europeans during the 16th century. As an interoceanic connector, it was used to imagine commercial routes to the Orient and political projects that could sustain these dynamics. It was also conceived as a space to speculate on the potential wealth in the extreme south of the continent. In addition, on the Spanish side, some agents of the Crown considered it a strategic place for imperial projections and the defense of the Americas.
Discriminative Learning and the Lexicon: NDL and LDL
Authors: Chuang Yu-Ying , Baayen R. Harald
Published: December 2021

Naive discriminative learning (NDL) and linear discriminative learning (LDL) are simple computational algorithms for lexical learning and lexical processing. Both NDL and LDL assume that learning is discriminative, driven by prediction error, and that it is this error that calibrates the association strength between input and output representations. Both words’ forms and their meanings are represented by numeric vectors, and mappings between forms and meanings are set up. For comprehension, form vectors predict meaning vectors. For production, meaning vectors map onto form vectors. These mappings can be learned incrementally, approximating how children learn the words of their language. Alternatively, optimal mappings representing the end state of learning can be estimated. The NDL and LDL algorithms are incorporated in a computational theory of the mental lexicon, the ‘discriminative lexicon’. The model shows good performance both with respect to production and comprehension accuracy, and for predicting aspects of lexical processing, including morphological processing, across a wide range of experiments. Since, mathematically, NDL and LDL implement multivariate multiple regression, the ‘discriminative lexicon’ provides a cognitively motivated statistical modeling approach to lexical processing.
Morphological and Syntactic Variation and Change in Latin American Spanish
Authors: Lipski John M.
Published: December 2021

The Spanish language, as it spread throughout Latin America from the earliest colonial times until the present, has evolved a number of syntactic and morphological configurations that depart from the Iberian Peninsula inheritance. One of the tasks of Spanish variational studies is to search for the routes of evolution as well as for known or possible causal factors. In some instances, archaic elements no longer in use in Spain have been retained entirely or with modification in Latin America. One example is the use of the subject pronoun vos in many Latin American Spanish varieties. In Spain vos was once used to express the second-person plural (‘you-pl’) and was later replaced by the compound form vosotros, while in Latin America vos is always used in the singular (with several different verbal paradigms), in effect replacing or coexisting with tú. Other Latin American Spanish constructions reflect regional origins of Spanish settlers, for example, Caribbean questions of the type ¿Qué tú quieres? ‘What do you (sg)want?’ or subject + infinitive constructions such as antes de yo llegar ‘before I arrived’, which show traces of Galician and Canary Island heritage. In a similar fashion, diminutive suffixes based on -ico, found in much of the Caribbean, reflect dialects of Aragon and Murcia in Spain, but in Latin America this suffix is attached only to nouns whose final consonant is -t-. Contact with indigenous, creole, or immigrant languages provides another source of variation, for example, in the Andean region of South America, where bilingual Quechua–Spanish speakers often gravitate toward Object–Verb word order, or double negation in the Dominican Republic, which bears the imprint of Haitian creole. Other probably contact-influenced features found in Latin American Spanish include doubled and non-agreeing direct object clitics, null direct objects, use of gerunds instead of conjugated verbs, double possessives, partial or truncated noun-phrase pluralization, and diminutives in -ingo. Finally, some Latin American Spanish morphological and syntactic patterns appear to result from spontaneous innovation, for example, use of present subjunctive verbs in subordinate clauses combined with present-tense verbs in main clauses, use of ser as intensifier, and variation between lo and le for direct-object clitics. At the microdialectal level, even more variation can be found, as demographic shifts, recent immigration, and isolation come into play.
Intraspecific breakdown of self-incompatibility inPhysalis acutifolia(Solanaceae)
Authors: Pretz Chelsea , Smith Stacey D
Published: December 2021

Variation in mating systems is prevalent throughout angiosperms, with many transitions between outcrossing and selfing above and below the species level. This study documents a new case of an intraspecific breakdown of self-incompatibility in a wild relative of tomatillo, Physalis acutifolia. We used controlled greenhouse crosses to identify self-incompatible (SI) and self-compatible (SC) individuals grown from seed sampled across seven sites across Arizona and New Mexico. We measured 14 flower and fruit traits to test for trait variation associated with mating system. We also quantified pollen tube growth in vivo and tested for the presence of the S-RNase proteins in SI and SC styles. We found that seed from six of the seven sites produced SI individuals that terminated self-pollen tubes in the style and showed detectable S-RNase expression. By contrast, seed from one Arizona site produced SC individuals with no S-RNase expression. These SC individuals displayed typical selfing-syndrome traits such as smaller corollas, reduced stigma–anther distances, and a smaller pollen–ovule ratio. We also found plasticity in self-incompatibility as most of the SI individuals became SC and lost S-RNase expression roughly after 6 months in the greenhouse. While fixed differences in mating systems are known among the SI wild species and the often SC domesticated tomatillos, our study is the first to demonstrate intraspecific variation in natural populations as well as variation in SI over an individual’s lifespan.
Coronavirus GenBrowser for monitoring the transmission and evolution of SARS-CoV-2
Authors: Yu Dalang , Yang Xiao , Tang Bixia , Pan Yi-Hsuan , Yang Jianing , Duan Guangya , Zhu Junwei , Hao Zi-Qian , Mu Hailong , Dai Long , Hu Wangjie , Zhang Mochen , Cui Ying , Jin Tong , Li Cui-Ping , Ma Lina ,   Language translation team, Su Xiao , Zhang Guoqing , Zhao Wenming , Li Haipeng
Published: December 2021

Genomic epidemiology is important to study the COVID-19 pandemic, and more than two million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic sequences were deposited into public databases. However, the exponential increase of sequences invokes unprecedented bioinformatic challenges. Here, we present the Coronavirus GenBrowser (CGB) based on a highly efficient analysis framework and a node-picking rendering strategy. In total, 1,002,739 high-quality genomic sequences with the transmission-related metadata were analyzed and visualized. The size of the core data file is only 12.20 MB, highly efficient for clean data sharing. Quick visualization modules and rich interactive operations are provided to explore the annotated SARS-CoV-2 evolutionary tree. CGB binary nomenclature is proposed to name each internal lineage. The pre-analyzed data can be filtered out according to the user-defined criteria to explore the transmission of SARS-CoV-2. Different evolutionary analyses can also be easily performed, such as the detection of accelerated evolution and ongoing positive selection. Moreover, the 75 genomic spots conserved in SARS-CoV-2 but non-conserved in other coronaviruses were identified, which may indicate the functional elements specifically important for SARS-CoV-2. The CGB was written in Java and JavaScript. It not only enables users who have no programming skills to analyze millions of genomic sequences, but also offers a panoramic vision of the transmission and evolution of SARS-CoV-2.
Bringing Dignity to the Assessment of Safety for Children who Live with Violence
Authors: Alexander Kate , Humphreys Cathy , Wise Sarah , Zhou Albert
Published: December 2021

Fear dominates women and children’s experience of domestic violence. Fear of harm, and the consequences of others finding out, can mean mothers are reluctant to seek help. Ironically, these survival behaviours can be understood as non-protective by child protection practitioners. This article describes research undertaken in New South Wales (NSW) Australia to determine the impact on child protection practitioner perceptions of child safety when Response-Based Practice (RBP) questions are combined with the standard NSW Structured Decision Making (SDM) safety assessment. RBP reflects core social work values through questions that explore how victims respond to, resist and manage violence. A vignette experiment with a between-subjects design was used to compare child safety assessments by practitioners who watched an interview guided by SDM alone and practitioners who watched an interview using the combined ‘treatment’ (SDM+RBP) approach. Participants (N = 1,041) were randomly assigned to SDM and treatment groups. Participants who watched the treatment approach were significantly more likely to assess the mother as cooperative and protective and significantly less likely to indicate that the children would be taken from her care. Thus, the results demonstrate that understanding how women manage violence changes practitioner views about maternal protectiveness and child safety.
Design and simulation analysis of high-temperature heat-storage combined-circulation system
Authors: Zhang Hongwei , Liu Junqing , Liang Wenbin , Shan Hongqing , Wang Jie
Published: December 2021

In view of the continuous increase in the proportion of renewable energy connected to the grid in China and the increasing peak-to-valley difference in electricity demand on the power grid, this paper proposes a high-temperature thermal-storage combined-cycle power-generation system. Using Thermoflex thermal simulation analysis software, a high-temperature thermal-storage combined-cycle simulation analysis system model was established, and the influence of different initial temperatures and pressure ratios on the combined-cycle system was analysed. Sensitivity analysis of factors such as electricity cost, annual operating hours, initial equipment investment, unit efficiency and other factors that affect the net income of the system was carried out. According to the current power-peak-shaving auxiliary service market in China, it is pointed out that high-temperature thermal-storage combined-cycle projects must be profitable and obtain good economic benefits. The results obtained, on the one hand, provide suggestions for the flexibility and transformation of current gas-fired steam generators for peak shaving and, on the other hand, provide references for the subsequent development of high-temperature thermal-storage combined-cycle demonstration projects.
Brain functional network abnormalities in parkinson’s disease with mild cognitive impairment
Authors: Suo Xueling , Lei Du , Li Nannan , Peng Jiaxin , Chen Chaolan , Li Wenbin , Qin Kun , Kemp Graham J , Peng Rong , Gong Qiyong
Published: December 2021

Mild cognitive impairment in Parkinson’s disease (PD-M) is related to a high risk of dementia. This study explored the whole-brain functional networks in early-stage PD-M. Forty-one patients with PD classified as cognitively normal (PD-N, n = 17) and PD-M (n = 24) and 24 demographically matched healthy controls (HC) underwent clinical and neuropsychological evaluations and resting-state functional magnetic resonance imaging. The global, regional, and modular topological characteristics were assessed in the brain functional networks, and their relationships to cognitive scores were tested. At the global level, PD-M and PD-N exhibited higher characteristic path length and lower clustering coefficient, local and global efficiency relative to HC. At the regional level, PD-M and PD-N showed lower nodal centrality in sensorimotor regions relative to HC. At the modular level, PD-M showed lower intramodular connectivity in default mode and cerebellum modules, and lower intermodular connectivity between default mode and frontoparietal modules than PD-N, correlated with Montreal Cognitive Assessment scores. Early-stage PD patients showed weaker small-worldization of brain networks. Modular connectivity alterations were mainly observed in patients with PD-M. These findings highlight the shared and distinct brain functional network dysfunctions in PD-M and PD-N, and yield insight into the neurobiology of cognitive decline in PD.
The “two-brain” approach reveals the active role of task-deactivated default mode network in speech comprehension
Authors: Liu Lanfang , Li Hehui , Ren Zhiting , Zhou Qi , Zhang Yuxuan , Lu Chunming , Qiu Jiang , Chen Hong , Ding Guosheng
Published: December 2021

Exhibiting deactivation and anticorrelation with task-positive networks, the default mode network (DMN) has been traditionally thought to be suppressed to support externally oriented cognitive processes during spoken language comprehension. In contrast, recent studies examining listener–listener intersubject correlation (ISC) have proposed an active role of DMN in language comprehension. How can we reconcile those seemingly conflicting results? This study adopted a “two-brain” paradigm and combined “within-brain” and “across-brain” analyses to address this issue. We found, despite being deactivated and anticorrelated with the language network (LN) and executive control network (ECN), both the anterior and posterior DMN in the listeners’ brains were temporally coupled with the homologous networks in the speaker’s brain. Interestingly, the listener–speaker neural couplings persisted even after controlling for listener–listener ISC. Moreover, the coupling strength of posterior DMN positively correlated with the listeners’ speech comprehension. Further dynamic causal modeling showed that the LN and ECN, the anterior DMN, and the posterior DMN occupied the bottom, intermediate, and top layers of a hierarchical system, respectively. We suggest the DMN may primarily serve as an internal module that cooperates with the externally oriented modules, potentially supporting the transformation of external acoustic signals into internal mental representations during successful language comprehension.
Joint Associations of Multiple Lifestyle Factors With Risk of Active Tuberculosis in the Population: The Singapore Chinese Health Study
Authors: Li Huiqi , Chee Cynthia B E , Geng Tingting , Pan An , Koh Woon Puay
Published: December 2021

Background

Little is known about the joint associations of multiple lifestyle risk factors including smoking, low body mass index, physical inactivity, alcohol consumption, and low diet quality with risk of active tuberculosis.

Methods

We analyzed data from the Singapore Chinese Health Study, a prospective cohort study of 63 257 Chinese adults aged 45–74 years enrolled between 1993 and 1998. Incident cases of active tuberculosis were identified via linkage with the National TB Registry through 31 December 2016. Cox proportional hazards regression models were used to compute hazard ratios (HRs) and 95% confidence intervals (CIs) of tuberculosis risk in relation to the combined scores of lifestyle risk factors.

Results

Compared with participants with none of the risk factors, the adjusted HRs (95% CI) of active tuberculosis for participants with 1, 2, 3, 4, and 5 risk factors were 1.24 (1.02–1.51), 1.84 (1.51–2.23), 2.52 (2.03–3.14), 4.07 (3.07–5.41), and 9.04 (5.44–15.02), respectively (Ptrend < .0001). The HR for those with 5 factors was ~1.5 times the product of individual risk estimates from the 5 factors on a multiplicative scale. The stepwise increase in risk of active tuberculosis with increasing number of lifestyle risk factors was significantly stronger in participants with diabetes than their counterparts without diabetes at recruitment (Pinteraction = .01).

Conclusions

Multiple lifestyle risk factors were associated with risk of active tuberculosis in a synergistic manner. Our findings highlight the importance of public health programs and interventions targeting these factors simultaneously to reduce the tuberculosis burden among the general population.
Importance of a usual source of care in choosing low-priced generic drugs: a cross-sectional study
Authors: Son Kyung-Bok , Lee Eui-Kyung
Published: December 2021

Background

The potential to lower pharmaceutical spending exists if physicians prescribe low-priced generics. This study aimed to empirically investigate the determinants of choosing low-priced generic drugs in South Korea.

Methods

The 2018 HIRA-NPS dataset was used for this study. Among 1.45 million individuals, we identified the patients who were prescribed atorvastatin 10 mg for more than 60 days in 2018 as the study subjects, separated the subjects into high- and low-priced groups based on their average unit price, and applied a series of logistic regression models to elucidate the factors affecting low-priced drug choice.

Results

Out of 60,984 subjects, only 10,228 (17%) were categorized into the low-priced group. The majority of the subjects (31%) were prescribed drugs at the maximum reimbursement price. Age of the subject, the frequency of visits to the institution, the existence of a usual source of care, and the institution type that a subject mainly visited for prescriptions were associated with being prescribed low-priced generics.

Conclusion

The association of being prescribed low-priced generics with the primary care institution and the usual source of care could be interpreted as evidence for the role of primary care in the continuity of patient-centred care. Creating health systems under which professionals act as perfect agents of a patient and/or an insurer is required.
Bidirectional Within- and Between-Person Relations Between Physical Activity and Cognitive Function
Authors: Stenling Andreas , Eriksson Sörman Daniel , Lindwall Magnus , Machado Liana
Published: December 2021

Objectives

To examine bidirectional within- and between-person relations between physical activity and cognitive function across 15 years.

Methods

Participants (N = 1,722, age range 40–85 years, 55% women) were drawn from the Betula prospective cohort study. We included 4 waves of data. Bivariate latent curve models with structured residuals were estimated to examine bidirectional within- and between-person relations between physical activity and cognitive function (episodic memory recall, verbal fluency, visuospatial ability).

Results

We observed no statistically significant bidirectional within-person relations over time. Higher levels of physical activity at baseline were related to less decline in episodic memory recall. Positive occasion-specific within- and between-person relations were observed, with the most consistent being between physical activity and episodic memory recall.

Discussion

The lack of bidirectional within-person relations indicates that shorter time lags may be needed to capture time-ordered within-person relations. The link between higher physical activity at baseline and less decline in episodic memory recall over time may indicate a protective effect of physical activity on episodic memory recall.