bluuebunny/crossref_metadata_2025 huggingface dataset:
The ten commandments of translational research informatics
Authors: Hulsen Tim
Published: September 2019

Translational research applies findings from basic science to enhance human health and well-being. In translational research projects, academia and industry work together to improve healthcare, often through public-private partnerships. This “translation” is often not easy, because it means that the so-called “valley of death” will need to be crossed: many interesting findings from fundamental research do not result in new treatments, diagnostics and prevention. To cross the valley of death, fundamental researchers need to collaborate with clinical researchers and with industry so that promising results can be implemented in a product. The success of translational research projects often does not depend only on the fundamental science and the applied science, but also on the informatics needed to connect everything: the translational research informatics. This informatics, which includes data management, data stewardship and data governance, enables researchers to store and analyze their ‘big data’ in a meaningful way, and enable application in the clinic. The author has worked on the information technology infrastructure for several translational research projects in oncology for the past nine years, and presents his lessons learned in this paper in the form of ten commandments. These commandments are not only useful for the data managers, but for all involved in a translational research project. Some of the commandments deal with topics that are currently in the spotlight, such as machine readability, the FAIR Guiding Principles and the GDPR regulations. Others are mentioned less in the literature, but are just as crucial for the success of a translational research project.
Wellbeing series: Meditation for paramedics
Authors: Colbeck Marc
Published: September 2019

In this wellbeing series we present practical advice for prehospital care providers, responders, and other shift workers. These articles are produced by experts in their field. Many of these topics were presented at the Irish College of Paramedics Wellbeing Symposium in University College Cork in May 2019.
Assessment of research methodology concepts through critical appraisal among undergraduate medical students and their perception: A single center study
Authors: Bhatti Mahwish Majid , Naseem Sajida , Din Imad ud , Naeem Zahid , Ahmad Rifat Nadeem
Published: September 2019

Introduction: Evidence based medicine is an interplay of individual clinical acumen and best available evidence through scientific systematic research. With the advent of modern medicine in the last two centuries, medical education has seen and continues to experience its revolutionary effects. An important aspect in this regard is the integration of biomedical research.

Objectives: To assess the research skills among undergraduate medical students exposed to the teaching of research longitudinally through all the five academic years.

Methodology: A mixed method study was conducted in which third year MBBS students were assessed in a group through power point presentation regarding different concepts of research while critically appraising a research article. Quantitative and qualitative data were collected. Descriptive statistics were calculated, as well as thematic analysis was done.

Results: From a total of 102 participants, 58 were male and 42 were female. Majority of the participants (81.4%) achieved an average or a good score and only 18.6% achieved a poor score. Six themes were generated. General enthusiasm about the activity was noted among participants who considered it beneficial. However, only a few were in the favor of incorporating this activity as a mandatory component in undergraduate studies.

Conclusion: Incorporating research in a mandatory longitudinal theme component as part of undergraduate medical studies seems a potential method of laying the foundation for future physician scientists.
Meta-Analytic Review of Sport Consumption: Factors Affecting Attendance to Sporting Events
Authors: Kim Yukyoum , Magnusen Marshall , Kim Minjung , Lee Hyun-Woo
Published: September 2019

Abstract: Understanding what leads individuals to consume the product of sport is central to the study of the sport management discipline. Though the study of sport consumer behavior benefits from an extensive body of work, many key issues (e.g., external validity concerns) still require attention. This meta-analysis provides a comprehensive and systematic empirical review of the sport (mostly team sport) attendance literature. Specifically, this study examines the relationship between three categories of predictors (fan-focused, relationship-focused, and product-focused) and sport attendance. Also examined are four categories of moderators (sport level, culture, gender, and sample type). The present meta-analysis integrates 352 effect sizes based on 172,142 participants from 123 independent samples drawn from 119 studies. The results of this study, such as the relationship-focused factors of identification and commitment having the largest effects on attendance of all the proposed antecedents, offer a variety of important implications for improving how sport attendance is studied and marketing initiatives are planned and executed.
How Major League Teams Hire Entry-Level Ticket Sales Representatives: A Qualitative Analysis
Authors: Popp Nels , Harrolle Michelle , Wells Janelle E.
Published: September 2019

Abstract: Maintaining a robust salesforce is critical for nearly any business. The sport industry is no exception, as salespeople help sport organizations generate essential ticket revenue. While the sport industry is a popular career option for young professionals, relatively few aspiring sport managers desire to work in sales. As such, entry-level sport ticket sales positions experience high turnover. The purpose of this study is to assess the hiring processes of recruitment, evaluation, and selection of sales candidates among North American professional sport leagues. Qualitative interviews were conducted with 21 ticket sales hiring managers from teams in the four major North American professional sports leagues (MLB, NBA, NFL, and NHL). Data analysis from interviews revealed four primary themes: (a) recruitment as an active and continuous process, (b) contrasting approaches to interviewing, (c) hiring managers’ preferences for ideal candidates, and (d) challenges assessing candidates. Several subthemes were identified. Implications for faculty, practitioners, and students are discussed.
A ARTICULAÇÃO ENTRE A EDUCAÇÃO BÁSICA E O ENSINO SUPERIOR: CONTRIBUIÇÕES DOS MESTRADOS PROFISSIONAIS EM EDUCAÇÃO
Authors: Lima Francine , Ferreira Helena , Villarta-Neder Marco
Published: September 2019

Este artigo elege como objeto de discussão um dos objetivos precípuos dos mestrados profissionais em educação, qual seja, a articulação entre o ensino superior e a educação básica. O objetivo consiste em inventariar as contribuições propiciadas pelo Programa de Mestrado Profissional em Educação (PPGE) da Universidade Federal de Lavras (MG) para a atuação dos egressos na educação básica. O trabalho apresenta as especificidades das propostas dos mestrados profissionais em educação, discute os processos de articulação entre ensino superior e educação básica e analisa o contexto dos processos de formação de professores e de constituição de sujeitos. O trabalho apresenta uma análise das percepções dos egressos acerca da efetividade das ações formativas para os diversos campos de atuação de professores da educação básica. As discussões empreendidas demonstraram que a articulação entre ensino superior e a educação básica ainda constitui um desafio, uma vez que as contribuições ainda demandam um tratamento que permita a criação de estratégias para uma maior visibilidade das ações/pesquisas desenvolvidas e a sistematização das percepções dos egressos. Nesse sentido, a contribuição deste trabalho se consubstancia na provocação de uma reflexão sobre a efetividade dos Mestrados Profissionais para uma formação para a docência e para a gestão escolar na educação básica, evidenciando um posicionamento que considera que o projeto e as ações formativas dessa modalidade se constituem como práticas sociais, que, por sua vez, promovem a constituição de sujeitos, propiciam a compreensão de processos educativos, ampliam as bases epistemológicas e fortalecem a aproximação entre agências educativas e agentes formadores.
O USO DE PLATAFORMAS DIGITAIS E FLIPPED CLASSRROM EM UMA DISCIPLINA NO MESTRADO PROFISSIONAL EM EDUCAÇÃO
Authors: De Souza Mariana , Bussolotti Juliana , Ribeiro Suzana , Da Cunha Virgínia Mara
Published: September 2019

O presente artigo tem por objetivo apresentar as estratégias metodológicas utilizadas na disciplina obrigatória “Escola, Currículo e Diversidade” do Mestrado Profissional em Educação da Universidade de Taubaté nos anos de 2017 e 2018, a partir de seu desenho curricular, estabelecendo uma análise com a avaliação final da disciplina. Esse estudo retrata a participação de 66 mestrandos, sendo 45 no ano de 2017, distribuídos em duas turmas, uma com 21 alunos e outra com 24, e 21 alunos no ano de 2018. A disciplina, composta por 15 semanas de aulas, teve seu material preparatório disponibilizado em duas plataformas digitais distintas: Google Drive no ano de 2017 e Rede Social Cuboz no ano de 2018. Todas as aulas se organizaram a partir da Flipped Classroom, por meio da qual os mestrandos deveriam ler os textos e demais materiais recomendados, responder as questões de um formulário eletrônico e envia-lo antes da aula. As aulas aconteceram a partir do uso de metodologias participativas, por meio das quais os mestrandos puderam compartilhar dúvidas, aprendizagens e construir conhecimento. Os dados aqui apontados demonstram que a organização curricular e a diversificação metodológica contribuem para: (i) a organização do trabalho, (ii) o desenvolvimento da autonomia de estudos para mestrandos iniciantes, (iii) a interação e participação do grupo quanto às temáticas propostas; (iv) a análise dos assuntos e sua correlação com os temas de pesquisa.
Performance Analysis of Repeated Index Modulation with Coordinate Interleaving over Nakagami-m Fading Channel
Authors: Huyen Le Thi Thanh , Nam Tran Xuan
Published: September 2019

In this paper, a new Space-Time Block Coded Spatial Modulation (SM) scheme based on the Golden Code, called the In this paper, we evaluate the symbol error performance of an extended Index Modulation for Orthogonal Frequency Division Multiplexing (IM-OFDM), namely repeated index modulation-OFDM with coordinated interleaving (abbreviated as ReCI), over the Nakagami-m fading channel. The ReCI system attains higher error performance than the conventional IM-OFDM with coordinate interleaving (IMOFDM-CI). In order to investigate the system performance over the Nakagami-m fading channel, we derive the closed-form expressions for the symbol error probability (SEP) and the bit error probability (BEP). The analytical results give interesting insights into the dependence of SEP on system parameters. Their tightness is also validated by numerical results, which show that our proposed scheme can provide considerably better error performance than the conventional IM-OFDM and IM-OFDM-CI at the same spectral efficiency. DOI: 10.32913/mic-ict-research.v2019.n1.863
Um af-liði í ópersónulegri þolmynd
Authors: Ingason Anton Kar , Sigurðsson Einar Freyr
Published: September 2019

This paper discusses the use of ‘by’-phrases in Impersonal Passives in Icelandic. It has been claimed in the literature on Icelandic syntax that ‘by’-phrases that express the agent are not very good or even ungrammatical in Impersonal Passives. The pa-per shows that this point of view oversimplifies the facts because various examples of this pattern can be found in natural data and these examples do not seem to reflect mistakes in linguistic performance. We discuss examples from the Icelandic treebank and from the web and we suggest that ‘by’-phrases are more likely to be used in Impersonal Passives if they involve new information and/or if they are heavy. One of the conclusions of the article is that large and well annotated corpora are important for linguistic research that focuses on rare constructions.
Media for sex education in elementary school: Which one is better?
Authors: Maharani Luluk Nandya , Sanyata Sigit
Published: September 2019

In the last decade, the problem of child sexual violence is very prevalent, therefore the need for the application of sex education in elementary school children. This is done to provide knowledge about sex education that is tailored to the stage of child development and to avoid the danger of predators of violence and sexual abuse. Providing knowledge about sex education will be better if there are supporting media in its delivery. Regarding the good media in teaching sex education to elementary school children there are currently two namely electronic and print media. Although there are two media to introduce sex education, but they have not shown maximum results, both media have their advantages and disadvantages. This paper aims to review the literature in the delivery of sex education in elementary schools using electronic and print media. The results or reviews in this discussion are expected to provide information that can be used as a theoretical and methodological basis for further research in the use of sex education delivery media for elementary students.
The Future of Mental Health Nursing Practice In Saudi Arabia: A Delphi Study
Authors: Alzghool Muneeb Mohammed , Al-Bakiri Abdulrahman Mohammed
Published: September 2019

Background: Mental health nursing education, research, and practice is well examined in North America and Europe. But, evidence in literature relating to the future of nursing practice in Saudi Arabia is very limited.

Purpose: The aim of this study was to explore the future directions of mental health nursing practice in Saudi Arabia by obtaining expert consensus and to recommend a future agenda for policymakers and researchers in the field of mental health nursing.

Methodology: A Delphi method was used. The data was collected over three rounds. For the first round, the researcher utilized open-ended question questionnaire. Following the content analysis of the open-ended questions (639) responses were elicited. A 33 items questionnaire was then constructed with five major categories and were utilized later during the second and third round of the study. The initial sample consisted of (N= 87 males) and (N=63 females), Saudi and Non-Saudi. The rank of panel members were staff nurses, nurse managers, lecturers, assistant professors, associate professors, and professors. The second round.

consisted of (N=140), while the third round consisted of(N=120) of the experts panel who agreed to continue in participating in the study.

Results: The results of the study showed that consensus among the experts was reached on 19 elements with agreement level of 80% or more. In conclusion, it was apparent that expert panel believes that there are many elements that should shape up the future of mental health nursing practice by 2025. However, less emphasis was apparent from the panel ratings on items such as the stigma associated with mental illness and mentally ill people.

Conclusions: The results of the study showed that 19 items have achieved 80% and over of consensus and agreement by the experts. Most of the remaining items reached an agreement level by the experts panel ranging between 60% to 79%, which suggests that the future directions of mental health nursing practice in Saudi Arabia is not only limited to those items that achieved consensus by 80% or more, and that policymakers and nurse researchers should consider both thoroughly.
KORELASI ANTARA KADAR SUPEROKSIDA DISMUTASE DENGAN MALONDIALDEHID PADA JARINGAN KERATOSIS SEBOROIK
Authors: Widiatmoko Arif , SHW Tantari , Ardian Yusuf
Published: September 2019

Keratosis seboroik (KS) merupakan tumor jinak epidermis dan sering dikeluhkan karena secara kosmetik mengganggu penampilan. Superoksida dismutase (SOD) merupakan salah satu antioksidan enzimatik intraseluler yang efektif mencegah stres oksidatif sebagai penyebab utama proses penuaan dan pembentukan lesi tumor keratosis seboroik. Malondialdehid (MDA) adalah senyawa dialdehida produk metabolit oksidasi membran sel oleh radikal bebas. Kadar antioksidan yang rendah biasanya disertai dengan peningkatan kadar MDA.Penelitian ini bertujuan untuk mengetahui korelasi kadar SOD dan kadar MDA jaringan pada pasien keratosis seboroik.Desain penelitian ini adalah analitik observasional potong lintang. Subjek penelitian didapatkan dari Poliklinik Kulit dan Kelamin RSUD dr. Saiful Anwar Malang secara consecutive sampling. Semua proses diagnosis, terapi pengangkatan lesi, serta pemeriksaan kadar SOD dan MDA jaringan keratosis seboroik dilakukan terhadap masing-masing subjek penelitian. Pemeriksaan SOD dan MDA jaringan menggunakan cara enzyme-link immunosorbent assay (ELISA) Bioassay. Uji normalitas data menggunakan uji Kolmogorov-Smirnov. Uji korelasi menggunakan uji Pearson. Analisis statistik menggunakan program Statistical Package for Social Sciences (SPSS) versi 15.Subjek penelitian yang didapatkan sebanyak 20 pasien. Rerata kadar SOD jaringan sebesar 0,7665 Î¼M/L dan rerata kadar MDA jaringan sebesar 0,6727 Î¼M/L. Koefisien korelasi antara kadar SOD jaringan dengan kadar MDA jaringan sebesar -0,447 dengan nilai p=0,048. Penelitian ini menunjukkan bahwa semakin rendah kadar SOD akan semakin tinggi kadar MDA pada jaringan keratosis seboroik.Kata kunci: keratosis seboroik, SOD, MDA
Determinan Kejadian Bayi Berat Lahir Rendah (BBLR) di RS Panembahan Senopati Bantul
Authors: Arsesiana Angga , Kumala Desi , Alestari Rena Oki
Published: September 2019

Latar Belakang: Berat badan lahir rendah adalah salah satu indikator kesehatan anak dan merupakan faktor utama dalam peningkatan angka kematian, morbiditas dan disabilitas neonatal, bayi dan anak-anak.Tujuan: Penelitian ini bertujuan untuk mengetahui dan menganalisis terjadinya BBLR di Rumah Sakit Panembahan Senopati Bantul.Metode: Ini adalah studi analitik observasional dari desain kasus kontrol. Populasi penelitian ini adalah semua ibu yang melahirkan dengan berat badan lahir rendah di Rumah Sakit Panembahan Senopati. Sampel penelitian ini adalah ibu melahirkan berat badan lahir rendah (case) sebanyak 162 ibu dan ibu melahirkan berat lahir normal (kontrol) sebanyak 162. Analisis dilakukan secara deskriptif, chi square dan regresi logistik.Hasil: Hasil penelitian ini menunjukkan bahwa penentu berat lahir rendah adalah Hb <11 g / dL dengan nilai OR 19,02. Selain itu ada juga faktor lain yang mempengaruhi terjadinya BBLR adalah komplikasi kehamilan dengan nilai OR 13,28, paritas dengan nilai OR 10,37, penyakit kronis dengan nilai OR 8,18, dengan nilai OR 3,92 dan usia kehamilan dengan OR 3,88. Dianjurkan bagi wanita hamil untuk secara rutin melakukan pemeriksaan kehamilan untuk memantau kondisi janin sehingga faktor penyebab BBLR dapat dideteksi sejak dini.Kesimpulan: Penentu berat lahir rendah adalah tingkat Hb <11gr / dL dengan nilai OR 19,02.Â Kata kunci: Berat lahir rendah, kecelakaan, determinanÂ Â ABSTRACTÂ­Â­BACKGROUND Low birth weight is one indicator of child health and is a main factor in increased mortality, neonatal morbidity and disability, infants and children.OBJECTIVE This study aims to determine and analyze the occurrence of low birth weight in Panembahan Senopati Bantul Hospital.METHODS This was an observational analytic study of case-control design. The population of this study were all mothers who gave birth to low birth weight in Panembahan Senopati Hospital. The sample of this research is mother giving birth of low birth weight (case) as much as 162 mother and mother giving birth of normal birth weight (control) as much as 162. Analysis is done descriptive, chi square and logistic regression.RESULT Result of this research shows that the determinant of low birth weight is Hb <11 g / dL with OR value of 19,02. In addition there are also other factors that affect the occurrence of low birth weight is pregnancy complications with the value of OR 13.28, parity with the value of OR 10.37, chronic disease with OR value of 8.18,Â  with OR value of 3.92 and gestational age with the OR 3.88. It is recommended for pregnant women to routinely conduct pregnancy examination to monitor condition of fetus so that cause factor of LBW can be detected early.CONCLUSION Determinant of low birth weight is Hb level < 11gr/ dL with OR value 19,02.Â Keyword: Low birth weight, accident, determinantÂ
Hubungan Tingkat Pengetahuan Dan Sikap Suami Terhadap Pemberian Imunisasi Bcg Pada Bayi Di Desa Lumban Suhi Kecamatan Pagururan Kabupaten Samosir
Authors: Situmorang Lina Kristia Winda , Munthe Juliana
Published: September 2019

Latar Belakang Pada tahun 2015 WHO telah mencanangkan program imunisasi sejak tahun 1974 dengan EPI. IndonesiaÂ  memiliki cakupan rendah imunisasi BCG pada tahun 2014 yaitu 92,3% dan menurun pada tahun 2015 sebesar 86,54%, angka belum mnecapai targer 2015 yaitu 91%. BCG adalah cairan kekebalan aktifÂ  terhadap penyakit tuberkulosis ( TBC) diberikan 1 kali pada usia 2 buan yang dimasukkan kedalam tubuh.Tujuan Penelitian Untuk mengetahui Hubungan tingkat pengetahuan dan sikap suami terhadap pemberian imuisasi dasar BCG pada bayi di Desa Lumaban Suhi Kecamatan Pangururan Kabupaten Samosir.Metode Penelitian Jenis penelitian ini yaitu analitik koleratif yaitu menganalisa hubungan antara variabel dengan rancangan cross sectional denagn menggunakan data primer yang didapat dari kuesioner dimana sampel sebanyak 30 orang suami yang mempunyai anak 0-2 bulan.Hasil Penelitian Hasil penelitian menunjukkan bahwa berpengetahuan cukup/kurang dengan sikap yang tidak baik dalam pemberian imunisasi BCG yaitu sebanyak 16 orang ( 61,5 %). Hasil uji Chi Square menunjukkan bahwa p= 0,024 artinya ada hubungan antara pengetahuan dan sikap suami dalam pemberian imunisasi BCG pada bayi.Kesimpulan Terdapat hubungan signifikan antara sikap dan pengetahuan suami terhadap pemberian imunisasi pada bayi usia 0-2 bulan dan kekuatan hubungan termasuk kuat. Hasil penelitian juga dapat disimpulkan bahwa kurangnya pengetahuan dan sikap suami berdampak pada tidak diberikanya imunisasi BCG relatif besar.Â Kata Kunci : Pengetahuan, Sikap Suami, Imunisasi BCG, Bayi
Penyuluhan Kesehatan Menggunakan Survivor Dengan Non Survivor Untuk Meningkatkan Perilaku Tentang Pemeriksaan Payudara Sendiri Pada Wanita Usia Subur Di Yogyakarta
Authors: Lestari Rena Oki , Arsesiana Angga , Widyandini Meyska
Published: September 2019

BACKGROUND: Cancer disease is one of the main causes of the death in the worldwide. However,the appropriate ways in improving breast self-examination behavior (SADARI) in productive fertile woman is not discovered yet.OBJECTIVE: The aims of this study were to obtain the information about the use of survivors and nonsurvivor of breast cancer in improving the behavior ofÂ Â  productive fertile woman. In addition, measuring how farthe impact of the characteristic of the respondents' behavior.METHODS The type of this study was Quasi Experimental, pretest posttest control group design, using female respondents in fertile aged, aged 20-30 years from 78 respondents, which wasrandomly selected. Independent variable in research was health counseling using survivor asresource with non survivor of breast cancer. The dependent variable in this study was knowledge, attitude, and skill. The instruments used to measure knowledge and attitudes were questionnaires, whilethe skills were measured by using the BSE, Breast Self-Examination, (SADARI) checklist sheet. The data obtained were analyzed by using Independent sample T Test and Mancova test with significant level of Î±: 0,05.RESULTS Â The results showed that there was a significant difference in the knowledge and skill of the productive women between counseling conducted by survivors with nonsurvivor (Ï-value 0.0001), while there was no significant improvement for the attitude (Ï-value 0.056). There was no characteristic influence on skill improvement, except work and experience factor (Ï-value 0.013 and Ï-value 0.039).CONCLUSION :Â Increasing the knowledge, attitudes and skills significantly differed between the use of survivor and nonsurvivor sources (p-value 0.0001) by controlling work and experience factors.Keywords: Survivor, nonsurvivor, breast cancer, counseling, Breast Self-Examination
Faktor yang Mempengaruhi Ibu Hamil Melakukan Kunjungan Antenatal Care
Authors: Ningrum Novalia Widya
Published: September 2019

Latar Belakang: Pelayanan kesehatan selama kehamilan merupakan hal yang penting bagi ibu hamil dan bayi yang dikandungnya. Penyebab kematian tersebut karena kurang optimalnya pelayanan kesehatan selama masa kehamilan. Berbagai hal yang mempengaruhi pelayanan antenatal; pengetahuan,umur,pekerjaan,paritas,letak geografis tempat tinggal dan motivasi baik dari ibu ataupun lingkungan yang diteliti d Puskesmas X.Tujuan Penelitian: Menganalisis Faktor-faktor yang Mempengaruhi Ibu hamil Melakukan Kunjungan Antenatal Care di Puskesmas X.Metode : Penelitian menggunakan observasional kuantitatif dengan pendekatan cross sectional. Populasi dan sampel adalah ibu hamil TM III yang berada di wilayah kerja Puskesmas Takisung bulan April-Juni 2017 berjumlah 224 orang, di ambil dengan sampel minimal 30 orang. Teknik pengambilan sampel Purposive Sampling, dianalisis menggunakanÂ  uji Chi-square.Hasil : Analisis uji Chi-squareÂ  Faktor usia (p= 0,456 > Î±= 0,10) dan pengetahuan Ibu hamil TM III (p=0,926> Î± = 0,10, maka tidak adanya pengaruh umur dan pengetahuan terhadap kunjungan ANC. Faktor pekerjaan (p= 0,046 < Î± = 0,10), jumlah paritas (p=0,068 < Î± = 0,10), letak geografis (p=0,005 < Î± = 0,10), motivasi (p=0,001< Î± = 0,10),maka adanya pengaruh faktor pekerjaan, paritas, letak geografis dan motivasiÂ  terhadap kunjungan ANC.Simpulan: Faktor pekerjaan,jumlah paritas, letak geografis tempat tinggal, motivasi berpengaruh pada ibu hamil TM III dalam melakukan kunjungan Antenatal Care.Â Kata Kunci : Antenatal Care, letak geografis, motivasi, paritas, pekerjaan, pengetahuan, umur.
Analisis Kepuasan Pasien Peserta BPJS Terhadap Kualitas Pelayanan Asuhan Persalinan di RSUD Dr. H. Moch. Ansari Saleh Banjarmasin
Authors: Zulliati Zulliati
Published: September 2019

Latar Belakang: Program BPJS merupakan sarana bagi masyarakat untuk mendapatkan jaminan kesehatan berupa pembiayaan kesehatan agar peserta memperoleh manfaat pemeliharaan kesehatan dan perlindungan dalam memenuhi kebutuhan dasar dalam hal ini program BPJS untuk Kesehatan Ibu dan Anak khususnya pertolongan persalinan.Tujuan: yaitu untuk menganalisa Kepuasan pasien merupakan tingkat perasaan pasien yang timbul sebagai akibat dari kinerja pelayanan kesehatan yang telah diperoleh setelah pasien membandingkan dengan apa yang diharapkan. Aspek kualitas pelayanan yang meliputi Tangible, Reliability, Responsiveness, Assurance, dan Empathy dapat digunakan sebagai gambaran melihat sejauh mana kepuasan pasien dalam menerima pelayanan yang diberikan.Metode: yang digunakan dalam penelitian ini adalah potong silang dengan Uji Rank Spearman dan path analisys untuk menganalisis pengaruh tiap subvariabel. Sampel pada penelitian ini adalah ibu bersalin peserta BPJS di ruang bersalin RSUD Dr. H. Moch. Ansari Saleh, dengan jumlah 99 orang.Hasil: Â Hasil penelitian yang dilakukan yaitu terdapat pengaruh kualitas pelayanan pertolongan persalinan terhadap kepuasan pasien peserta BPJS dengan hasil skor kepuasan gabungan yaituÂ  74.7% yang berarti variabel kualitas pelayanan pertolongan persalinan terhadap kepuasan pasien peserta BPJS dapat diintepretasikan puas untuk keseluruhan pelayanan yang diberikan. Hasil uji analisis jalur subavariabel yang paling dominan secara statistik mempengaruhi kepuasan pasien peserta BPJS adalah pada subvariabel tangible (bukti langsung) dengan total kontibusi sebesar 31.42%. dan pengaruh yang paling kecil yaitu terdapat pada variabel empathy (empati) yaitu dengan total kontribusi sebesar 9.08%.Simpulan: terdapat pengaruh yang signifikan kualitas pelayanan pertolongan persalinan terhadap kepuasan pasien peserta BPJS, dengan subvariabel yang paling berpengaruh yaitu pada subvariabel tangible.Â Kata Kunci: Kualitas Pelayanan, Pertolongan Persalinan, Kepuasan Peserta BPJS Kota Banjarmasin.
Antibiotic-Induced, Increased Conjugative Transfer Is Common to Diverse Naturally Occurring ESBL Plasmids in Escherichia coli
Authors: Liu Gang , Bogaj Karolina , Bortolaia Valeria , Olsen John Elmerdahl , Thomsen Line Elnif
Published: September 2019

Previously, we showed that cefotaxime (CTX) exposure increases conjugative transfer of a blaCTX–M–1 encoding IncI1 plasmid (IncI1/pST49/CTX-M-1) in Escherichia coli in a SOS-independent manner. This study aimed at investigating whether the observation was unique for that plasmid/strain/antibiotic combination or whether antibiotic-induced plasmid transfer (PT) is a more general phenomenon among plasmids in E. coli. Whole genome sequences of 25 E. coli strains were analyzed to identify different extended spectrum beta-lactamases (ESBL) plasmids enabling selection of a diverse collection of plasmids. Experiments were performed following exposure of these strains to 1/2 minimal inhibitory concentration (MIC) of CTX, ampicillin (AMP), or ciprofloxacin (CIP) before conjugation experiments. The frequency of PT was measured and compared to that of donors not exposed to antibiotics. Reverse-transcribed-quantitative real time polymerase chain reaction (RT-qPCR) was used to measure mRNA levels of five PT genes and two SOS response genes in donors exposed to antibiotics. The PT of eight strains (30.8% of strains tested) with IncI1/pST7/CTX-M-1, IncI1/pST49/CTX-M-1, IncI1/pST3/CTX-M-1, IncI1/pST293/CTX-M-1, IncI1/pST295/CTX-M-1, IncI1/pST16/CTX-M-55, and IncFII/CTX-M-14 (n = 2) plasmids was significantly increased following antibiotic exposure. CTX increased PT in all of these eight strain/plasmid combinations, AMP and CIP increased the PT in six and three strains, respectively. RT-qPCR showed that PT genes were up-regulated in the presence of the three antibiotics, whereas SOS-response genes were up-regulated only following CIP exposure. Our findings reveal that antibiotics can increase PT in E. coli strains with various ESBL plasmids. Thus, antibiotic-induced conjugative transfer of ESBL plasmids appears to be a common phenomenon in E. coli, having important implications for assessing the risks of antibiotic use.
Harvest Time Determines Quality and Usability of Biomass from Lowland Hay Meadows
Authors: Boob Meike , Elsaesser Martin , Thumm Ulrich , Hartung Jens , Lewandowski Iris
Published: September 2019

Species-rich hay meadows are usually managed extensively to maintain their biodiversity, with the harvested biomass traditionally being fed to ruminants for milk or meat production. The quality of the biomass is, however, variable, difficult to predict and often does not fulfil today’s requirements. This study established a field trial at two species-rich hay meadows to investigate the combined effect of fertilisation (none, phosphorus and potassium (PK), nitrogen, phosphorus and potassium (NPK)) and date of first cut (at different phenological stages) on biomass quality and quantity. In addition, the most suitable uses of the biomass were explored, including the alternatives biogas and combustion. After four years of the field trial, the stage of maturity at the time of first cut had a greater influence than extensive fertilisation on biomass quality. Dry matter yield (DMY) of the first cut was about 40%–60% of annual DMY (53.99 ± 12.51 dt ha−1 a−1) depending on site, fertilisation and harvest time. Fertilisation had a stronger effect than harvest time on DMY and annual methane yield. In most cases, there was no significant difference in chemical composition between biomass harvested at the end of the grass-flowering stage and at the seed-ripening stage. Thus, a late cut for hay proved to be the most flexible option.
A Rabbit Monoclonal Antibody against the Antiviral and Cancer Genomic DNA Mutating Enzyme APOBEC3B
Authors: Brown William L. , Law Emily K. , Argyris Prokopios P. , Carpenter Michael A. , Levin-Klein Rena , Ranum Alison N. , Molan Amy M. , Forster Colleen L. , Anderson Brett D. , Lackey Lela , Harris Reuben S.
Published: September 2019

The DNA cytosine deaminase APOBEC3B (A3B) is normally an antiviral factor in the innate immune response. However, A3B has been implicated in cancer mutagenesis, particularly in solid tumors of the bladder, breast, cervix, head/neck, and lung. Here, we report data on the generation and characterization of a rabbit monoclonal antibody (mAb) for human A3B. One mAb, 5210-87-13, demonstrates utility in multiple applications, including ELISA, immunoblot, immunofluorescence microscopy, and immunohistochemistry. In head-to-head tests with commercial reagents, 5210-87-13 was the only rabbit monoclonal suitable for detecting native A3B and for immunohistochemical quantification of A3B in tumor tissues. This novel mAb has the potential to enable a wide range of fundamental and clinical studies on A3B in human biology and disease.
Sulfuric Odor Precursor S-Allyl-l-Cysteine Sulfoxide in Garlic Induces Detoxifying Enzymes and Prevents Hepatic Injury
Authors: Yamaguchi Yusuke , Honma Ryosuke , Yazaki Tomoaki , Shibuya Takeshi , Sakaguchi Tomoya , Uto-Kondo Harumi , Kumagai Hitomi
Published: September 2019

S-Allyl-l-cysteine sulfoxide (ACSO) is a precursor of garlic-odor compounds like diallyl disulfide (DADS) and diallyl trisulfide (DATS) known as bioactive components. ACSO has suitable properties as a food material because it is water-soluble, odorless, tasteless and rich in bulbs of fresh garlic. The present study was conducted to examine the preventive effect of ACSO on hepatic injury induced by CCl4 in rats. ACSO, its analogs and garlic-odor compounds were each orally administered via gavage for five consecutive days before inducing hepatic injury. Then, biomarkers for hepatic injury and antioxidative state were measured. Furthermore, we evaluated the absorption and metabolism of ACSO in the small intestine of rats and NF-E2-related factor 2 (Nrf2) nuclear translocation by ACSO using HepG2 cells. As a result, ACSO, DADS and DATS significantly suppressed the increases in biomarkers for hepatic injury such as the activities of aspartate transaminase (AST), alanine transaminase (ALT) and lactate dehydrogenase (LDH), and decreases in antioxidative potency such as glutathione (GSH) level and the activities of glutathione S-transferase (GST) and glutathione peroxidase (GPx). We also found ACSO was absorbed into the portal vein from the small intestine but partially metabolized to DADS probably in the small intestine. In in vitro study, ACSO induced Nrf2 nuclear translocation in HepG2 cells, which is recognized as an initial trigger to induce antioxidative and detoxifying enzymes. Taken together, orally administered ACSO probably reached the liver and induced antioxidative and detoxifying enzymes by Nrf2 nuclear translocation, resulting in prevention of hepatic injury. DADS produced by the metabolism of ACSO in the small intestine might also have contributed to the prevention of hepatic injury. These results suggest potential use of ACSO in functional foods that prevent hepatic injury and other diseases caused by reactive oxygen species (ROS).
Chemical Composition and Antioxidant Activity of the Main Fruits Consumed in the Western Coastal Region of Ecuador as a Source of Health-Promoting Compounds
Authors: Guevara Mabel , Tejera Eduardo , Granda-Albuja María G. , Iturralde Gabriel , Chisaguano-Tonato Maribel , Granda-Albuja Silvana , Jaramillo-Vivanco Tatiana , Giampieri Francesca , Battino Maurizio , Alvarez-Suarez José M.
Published: September 2019

We studied 19 different tropical fruits traditionally consumed in the coastal lowlands of Ecuador to determine their chemical composition and antioxidant activity. Carambola (Averrhoa carambola L.) had the highest total phenolic, flavonoid, and total antioxidant capacity values, whereas guava fruits (Psidium guajava L.) had the highest vitamin C values. The main organic acids identified were lactic, citric, and acetic acids, and the highest amount of lactic acid was found in soursop fruits (Annona muricata L.), whereas Ecuadorian ivory palm (Phytelephas aequatorialis Spruce) and guava fruits had the highest acetic acid content. Guava also had the highest citric acid content; the highest concentration of oxalic acid was found in carambola. In terms of sugar content, giant granadilla (Passiflora quadrangularis L.) had the highest values of glucose, and red mombin (Spondias mombin L.) had the largest values for fructose and guava for sucrose. Chili pepper (Capsicum chinense Jacq) proved to be the main source of carotenoids, lutein, and β-carotene, anthocyanins, and vitamin C. The results here increase our knowledge regarding the composition of the main fruits consumed on the west coast of Ecuador to facilitate recommendations as potential sources of health-promoting compounds.
Assessment of Growing Thermal Conditions of Main Fruit Species in Portugal Based on Hourly Records from a Weather Station Network
Authors: Santos Mónica , Fraga Helder , Belo-Pereira Margarida , Santos João A.
Published: September 2019

Thermal conditions in mainland Portugal were evaluated using a new hourly database over the recent period of 2000–2018 (19 years). The number of hours within each different temperature interval was calculated from the long-term means of the hourly temperatures of a network of 63 meteorological stations. A geostatistical approach, using elevation, distance to coastline and latitude, was subsequently applied to provide gridded patterns at a high spatial resolution (1 km grid spacing). Eight fruit species (almond tree, carob tree, chestnut tree, citrus fruits, cork oaks, holm oaks, olive trees, and grapevines) were selected to assess their hourly thermal growing conditions. The results highlight the strong spatial variability of temperature levels in mainland Portugal, providing new insights into their spatial distribution. The number of hours in the year with cool conditions (4–12 °C) is higher in the northern-central regions, mainly in mountainous areas. Additionally, the number of hours in the year with temperate conditions (12–20 °C) emphasizes the importance of the distance to the coastline (maritime influence). The warm conditions (20–28 °C) are most prevalent in the south of the country and in the Douro valley, whereas the very warm conditions (number of hours with temperature between 28–36 °C) are essentially restricted to inner-southern Portugal and to the upper Douro valley. This study also reveals, with high accuracy, the thermal growing conditions of main fruit species in mainland Portugal, giving particular emphasis to olive trees and grapevines. These findings may help decision support systems providing more reliable and accurate guidelines to stakeholders, decision-makers, and farmers. The main maps are available in a widely used file format (shapefile), thus allowing their application to a wide range of other areas of interest.
Noise Reduction Mechanisms of an Airfoil with Trailing Edge Serrations at Low Mach Number
Authors: Tang Hui , Lei Yulong , Fu Yao
Published: September 2019

Trailing-edge serrations have proven to be valid applications of trailing edge noise mitigation for an airfoil, while the physical noise reduction mechanism has not been adequately studied. We performed simulations employing Large-eddy simulation and the Lighthill–Curle method to reveal the variation in the hydrodynamic field and sound source due to the trailing edge serrations. The grid resolution and computational results were validated against experimental data. The simulation results show that: the trailing edge serrations impede the growth of spanwise vortices and promote the development of streamwise vortices near the trailing edge and the wake; the velocity fluctuations in the vertical cross-section of the streamwise direction near the trailing edge are reduced for the serrated airfoil, thereby obviously reducing the strength of the pressure fluctuations near the trailing edge; and the trailing edge serrations decrease the distribution of the sound source near the trailing edge and reduce the local peak value of sound pressure level in a specific frequency range as well as the overall sound pressure level. Moreover, we observed that, in the flow around the NACA0012 airfoil, the location where the strong sound source distribution begins to appear is in good agreement with the location where the separated boundary layer reattaches. It is therefore effective to reduce trailing edge noise by applying serrations on the upstream of the reattachment point.
Thermal Infrared Small Ship Detection in Sea Clutter Based on Morphological Reconstruction and Multi-Feature Analysis
Authors: Li Yongsong , Li Zhengzhou , Zhu Yong , Li Bo , Xiong Weiqi , Huang Yangfan
Published: September 2019

The existing thermal infrared (TIR) ship detection methods may suffer serious performance degradation in the situation of heavy sea clutter. To cope with this problem, a novel ship detection method based on morphological reconstruction and multi-feature analysis is proposed in this paper. Firstly, the TIR image is processed by opening- or closing-based gray-level morphological reconstruction (GMR) to smooth intricate background clutter while maintaining the intensity, shape, and contour features of ship target. Then, considering the intensity and contrast features, the fused saliency detection strategy including intensity foreground saliency map (IFSM) and brightness contrast saliency map (BCSM) is presented to highlight potential ship targets and suppress sea clutter. After that, an effective contour descriptor namely average eigenvalue measure of structure tensor (STAEM) is designed to characterize candidate ship targets, and the statistical shape knowledge is introduced to identify true ship targets from residual non-ship targets. Finally, the dual method is adopted to simultaneously detect both bright and dark ship targets in TIR image. Extensive experiments show that the proposed method outperforms the compared state-of-the-art methods, especially for infrared images with intricate sea clutter. Moreover, the proposed method can work stably for ship target with unknown brightness, variable quantities, sizes, and shapes.
Non-Touch Sign Word Recognition Based on Dynamic Hand Gesture Using Hybrid Segmentation and CNN Feature Fusion
Authors: Rahim Md Abdur , Islam Md Rashedul , Shin Jungpil
Published: September 2019

Hand gesture-based sign language recognition is a prosperous application of human– computer interaction (HCI), where the deaf community, hard of hearing, and deaf family members communicate with the help of a computer device. To help the deaf community, this paper presents a non-touch sign word recognition system that translates the gesture of a sign word into text. However, the uncontrolled environment, perspective light diversity, and partial occlusion may greatly affect the reliability of hand gesture recognition. From this point of view, a hybrid segmentation technique including YCbCr and SkinMask segmentation is developed to identify the hand and extract the feature using the feature fusion of the convolutional neural network (CNN). YCbCr performs image conversion, binarization, erosion, and eventually filling the hole to obtain the segmented images. SkinMask images are obtained by matching the color of the hand. Finally, a multiclass SVM classifier is used to classify the hand gestures of a sign word. As a result, the sign of twenty common words is evaluated in real time, and the test results confirm that this system can not only obtain better-segmented images but also has a higher recognition rate than the conventional ones.
Separation of Cenospheres from Lignite Fly Ash Using Acetone–Water Mixture
Authors: Yoriya Sorachon , Intana Tanasan , Tepsri Phattarathicha
Published: September 2019

This work reports on the separation of cenospheres from lignite fly ash through a wet separation process-the sink-float method. A better quality of cenospheres could be achieved through a physical–chemical approach using an acetone–water mixture as a medium. This work aimed to elucidate the correlation between the structure, morphology, and composition and medium fraction variables, with data for the freshly prepared and the reused mixtures presented for comparison. The work covers a study of the macrocomponent composition of an Fe2O3–SiO2–Al2O3 system, highlighting the pair dependences of SiO2–Al2O3, Al2O3–Fe2O3, and SiO2/Al2O3–Al2O3 and revealing an interesting result in terms of geochemical characteristics categorizing the collected cenosphere fractions separated from high-calcium class C fly ash produced from a lignite coal power plant in Thailand (as magnetic cenospheres). The CaO and SO3 contents increased monotonically with increased water content, particularly for the CaO composition profile, which was found to be similar to the increased carbonate concentration measured from the mixtures after use. The physicochemical properties in terms of the self-association ability of the acetone–water mixing phase is believed to have played an important role in determining the intermolecular interactions and reactivity of ions in the liquid phase, consequently affecting the separation efficiency, recovery yield, and quality of cenospheres.
Harnessing the Full Potential of Industrial Demand-Side Flexibility: An End-to-End Approach Connecting Machines with Markets through Service-Oriented IT Platforms
Authors: Roesch Martin , Bauer Dennis , Haupt Leon , Keller Robert , Bauernhansl Thomas , Fridgen Gilbert , Reinhart Gunther , Sauer Alexander
Published: September 2019

The growing share of renewable energy generation based on fluctuating wind and solar energy sources is increasingly challenging in terms of power grid stability. Industrial demand-side response presents a promising way to balance energy supply and consumption. For this, energy demand is flexibly adapted based on external incentives. Thus, companies can economically benefit and at the same time contribute to reducing greenhouse gas emissions. However, there are currently some major obstacles that impede industrial companies from taking part in the energy markets. A broad specification analysis systematically dismantles the existing barriers. On this foundation, a new end-to-end ecosystem of an energy synchronization platform is introduced. It consists of a business-individual company-side platform, where suitable services for energy-oriented manufacturing are offered. In addition, one market-side platform is established as a mediating service broker, which connects the companies to, e.g., third party service providers, energy suppliers, aggregators, and energy markets. The ecosystems aim at preventing vendor lock-in and providing a flexible solution, relying on open standards and offering an integrated solution through an end-to-end energy flexibility data model. In this article, the resulting functionalities are discussed and the remaining deficits outlined.