bluuebunny/crossref_metadata_2025 huggingface dataset:
LEVERAGING IOT FOR SMARTER SUPPLY CHAIN MANAGEMENT AND LOGISTICS: A COMPREHENSIVE REVIEW AND FUTURE PERSPECTIVES
Authors: K Mrs. Madhura , B Dr. Raghavendra
Published: June 2024

The integration of the Internet of Things (IoT) in supply chain management and logistics has emerged as a promising approach to enhance operational efficiency, transparency, and agility. A comprehensive data analysis and interpretation of the integration of Internet of Things (IoT) technology in supply chain management and logistics. The study aims to assess the current level of IoT adoption, identify challenges faced during implementation, examine the relationship between IoT adoption and supply chain efficiency, explore potential benefits, and evaluate the impact of IoT integration on organizational performance and customer satisfaction. The data analysis is based on survey responses from diverse organizations operating in various industries. The survey investigated the extent of IoT adoption in different supply chain activities, such as inventory management, transportation, warehousing, and order fulfilment. The findings reveal that 75% of the surveyed organizations have partially adopted IoT in their supply chain operations, with varying degrees of implementation across different activities. Furthermore, the research identifies key challenges faced by organizations in implementing IoT, with the cost of implementation, integration with existing systems, and data security and privacy concerns being the most prominent hurdles. The study also explores the relationship between IoT adoption and supply chain efficiency. The data analysis demonstrates a positive correlation between IoT adoption and supply chain performance, with improvements observed in on-time delivery, order accuracy, and inventory turnover among the organizations that adopted IoT. The potential benefits of IoT adoption in supply chain management are investigated. The data analysis highlights the expected advantages of real-time tracking and visibility, predictive maintenance, and enhanced demand forecasting. Finally, the impact of IoT integration on overall organizational performance and customer satisfaction is evaluated. The data analysis indicates that a significant majority of organizations reported an overall improvement in performance after IoT integration, and a positive impact on customer experience and loyalty. In conclusion, this research provides valuable insights into the adoption and implications of IoT in supply chain management and logistics. The findings underscore the potential for IoT to drive efficiency and enhance customer satisfaction in the supply chain context. However, challenges related to cost, integration, and data security need to be addressed for successful implementation. The research contributes to a deeper understanding of leveraging IoT for smarter supply chain management and logistics, paving the way for further advancements and future perspectives in this rapidly evolving domain
CORPORATE GOVERNANCE ENUMERATION OF CONCEPTS, THEORIES AND REPORTS
Authors: V Dr. Mahalakshmi
Published: June 2024

Corporate Governance is about transparency and accountability, the openness, honesty and fairness in the management of an organization by its board in order to ensure sustainable efficiency and disclosure it is necessary to mandatorily follow the principles of Corporate Governance. To develop a strong base of CG rules, policies and norms, studying the backdrop and the evolution of CG in India is necessary. Various Countries have attempted to develop CG norms according to their business environment to create ethical way of conducting business. In the run of learning more about CG, the reports, theories, and models available are to be analyzed and understood to develop a strong CG of India. In this chapter enumerating the reports, theories, and models are considered to create strong base
FUTURE TRENDS IN BUSINESS MANAGEMENT CHALLENGES AND SUSTAINABILITY
Authors: Rathi Dr. Janvi
Published: June 2024

This study is based on the further trend in the business management sectors and its possible challenges. In addition, the trend for sustainability will be discussed. Here, the researcher has not only focused on further trends of business management but also focused on the present as well as traditional business trends. Here a glimpse has been provided to understand the innovation of smart technologies and their effect in developing a business organization in the current market. It has been observed that the demand for AI and automation or robotics systems in manufacturing products is high. However, the researcher has concentrated more on the trend on further business models and trends based on present business trends
INDUSTRY AND COMPANY ANALYSIS OF SULA VINEYARDS: UNVEILING THE SUCCESS OF INDIA'S WINE INDUSTRY LEADER
Authors: Sawant Durga Laxman
Published: June 2024

This project presents business and marketing analysis of Sura Vineyards, a well-known player in the Indian wine industry. India's wine industry has experienced significant growth in recent years and Sura Vineyards has emerged as a leader in this emerging sector. The first part of the review focuses on the overall wine industry in India and explores the historical development, current trends and future growth of this industry. Explore key concepts such as government regulations, consumer preferences, and distribution to understand business opportunities and challenges. Part Two covers detailed company analysis of Sula Vineyards. Explain the company's history, mission, and business goals. Analysis of Sula Vineyards' financial performance, including revenue, profitability and key financial ratios, to assess the health and profitability of the company. Additionally, the project evaluates Sula Vineyards' market positioning, competitive advantage, and the unique selling points that have contributed to its success. Furthermore, the project examines Sula Vineyards' supply chain management, production process, and quality control practices, emphasizing their commitment to sustainability and environmental responsibility. The company's marketing and branding strategies are also scrutinized to understand how they have captured and retained a significant market share in the Indian wine industry. Moreover, the project analyzes the management team and corporate governance practices at Sula Vineyards to assess their leadership and decision-making capabilities, which play a crucial role in the company's sustained growth and success. The findings of this industry and company analysis aim to shed light on the factors that have contributed to Sula Vineyards' ascendancy as a market leader in India's wine industry. By understanding the industry dynamics and the successful strategies adopted by Sula Vineyards, this study provides valuable insights for other players in the wine sector and offers a framework for strategic decision-making in the rapidly evolving Indian wine market
THE LASER RENAISSANCE: REVOLUTIONIZING DENTISTRY FOR THE MODERN AGE
Authors: Poonia Dr Nikita , Jain Dr Sheena , Jha Dr Swati , Mahajan Dr Siddhant
Published: June 2024

Traditional dental procedures have been transformed by lasers in dentistry, which provide accurate and minimally invasive solutions for a variety of applications. This chapter examines the various applications of lasers in dentistry, highlighting its effectiveness in managing both soft and hard tissues. Lasers are particularly good at preventing bleeding and improving vision during soft tissue treatments such as frenectomies and gingivectomies. Furthermore, periodontal therapy makes considerable use of lasers, which effectively disinfect periodontal pockets and stimulate tissue regeneration. Lasers are used in hard tissue applications to precisely ablate enamel, allowing cavities to be prepared with the least amount of harm to the neighboring good tooth structure. They are useful in caries removal because of their capacity to target carious lesions specifically, providing a cautious substitute for conventional drills. Additionally, lasers play a pivotal role in endodontic therapy, disinfecting root canals effectively and enhancing the success of root canal treatments. Beyond clinical applications, lasers in dentistry contribute to patient comfort by minimizing postoperative pain and reducing the need for anesthesia in certain procedures. While challenges such as cost and operator training persist, the continued integration of lasers into dental practice holds promise for advancing patient care, promoting faster healing, and shaping the future of dentistry towards more patient-friendly and efficient treatments
CLINICAL APPLICATIONS OF MINI IMPLANT
Authors: Yadav Dr. Deepti , Paul Dr. Rahul , Gulia Dr. Vandana , Gupta Dr. Mudita , Sharma Dr. Ish Kumar , Kesiezie Dr. Teisovinuo
Published: June 2024

Mini-implants, also known as temporary anchorage devices (TADs), have emerged as a transformative innovation in the field of orthodontics, providing a robust and versatile means of achieving precise tooth movement. These small, screw-like implants, strategically placed within the jawbone, offer significant advantages over conventional anchorage methods such as headgear and elastics. A primary application of mini-implants lies in cases demanding absolute anchorage, where tooth movement must occur without compromising the position of adjacent teeth. Mini-implants serve as steadfast anchor points, enabling orthodontists to execute controlled tooth repositioning without jeopardizing occlusal stability. This capability proves invaluable for correcting severe malocclusions, impacted teeth, and open bites. Mini-implants also play a pivotal role in accelerating tooth movement, a technique known as accelerated osteogenic orthodontics (AOO). By strategically placing mini-implants, orthodontists can apply precise forces directly to the teeth, facilitating faster and more efficient tooth movement compared to traditional methods. The clinical applications of mini-implants extend to a wide range of orthodontic procedures, including: Molar intrusion, Mesiodistal control, Space closure, Crossbite correction and Surgical orthodontics. Mini-implants are generally well-tolerated by patients, with minimal discomfort during placement and removal. The procedure is typically performed under local anesthesia and requires no incision or sutures. Moreover, mini-implants boast a high success rate, with a low incidence of complications such as implant failure or infection. In summary, mini-implants have revolutionized the field of orthodontics, offering a multitude of benefits over traditional anchorage methods. Their versatility, effectiveness, and patient-friendliness have solidified their position as a cornerstone of modern orthodontic treatment
SURGICAL CORRECTION OF COMMON DENTOFACIAL DEFORMITIES
Authors: Yadav Dr. Deepti , Paul Dr. Rahul , Gupta Dr. Mudita , Sharma Dr. Ish Kumar , Saini Dr. Prakher
Published: June 2024

The categorization of Mandibular Malformation and Temporomandibular Joint falls into several classifications Type I TMJ– Minimal hypoplasia of the glenoid fossa and the condyle- ascending ramus on either side characterizes mandibular deformity. The skeletal components are all present. Type IIA TMJ little degree of glenoid fossa and condyle-ascending ramus hypoplasia are present in TMJ-mandible malformation. Type IIB Condyles suffer from significant hypoplasia in mandibular deformity. Type III A mandibular defect known as glenoid fossa-mandibular malformation. Mandible is positioned backwardly is prevented from stopping against the skull base
PRECISION MEDICINE: UNLEASHING THE FUTURE OF HEALTHCARE
Authors: S Dr. Kavitha , Swathi N. L. , Riyazullah M. S. , Sree M. Mona , Priya Devi , Kumar Dr. Achukatla
Published: June 2024

Precision medicine is a healthcare approach that utilizes data from interdisciplinary field of diagnostics, genomics, proteomics, metabolomics, phenotypic characters and data from patients to generate insights to provide tailored therapy for better patient compliance. This chapter focuses on some of the futuristic trends in the field of medicine ranging from the role of pharmaceutical industry in precision health care to the use of pharmacogenomics that studies the genetic variations and the efficacy of therapy provided. The chapter also throws light upon fascinating approaches of futuristic diagnosis techniques that encourages the use of nanotechnology, AI/ML & NLP technologies for complex data analysis and monitoring treatment efficacy. We shall also discuss about Biohacking which objectifies the enhancement of general well-being and promoting lifespan
CORRELATION BETWEEN CARDIOVASCULAR DISEASE AND PULMONARY FUNCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: A LITERATURE REVIEW
Authors: Yadav Neha , Bajpai Aakanksha , Sharma Dr. Digvijay
Published: June 2024

The prevalence of diabetes in India has witnessed a persistent increase over recent decades, posing a substantial public health challenge. Importantly, the American Thoracic Society European Respiratory Society (ATS/ERS) guidelines underscore the lungs as a primary target organ for diabetic complications. Among individuals with type 2 diabetes mellitus, a notable decline in pulmonary function parameters, including Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV1), and Peak Expiratory Flow Rate (PEFR), indicative of a dominant restrictive pattern of pulmonary dysfunction, has been observed. Simultaneously, the initial diagnosis of type 2 diabetes often reveals a high prevalence of cardiovascular complications. Nevertheless, an unexplored nexus exists between cardiovascular disease and pulmonary function in type 2 diabetes. This study addresses this critical knowledge gap by conducting a meticulous review of 18 selected articles out of 40, aiming to elucidate the potential correlation between cardiovascular disease and pulmonary function in type 2 diabetes, thus contributing valuable insights to inform patient management and improve overall care outcomes in this population
SOME RESULTS ON THE REES ALGEBRAS AND ANALYTICALLY INDEPENDENT OF IDEALS
Authors: Singh Priti , Kumar Avinash
Published: June 2024

In this paper, we study analytically independent elements and the equations defining the Rees algebra of an ideal. Also we define the structure of the fiber cones, where elements are analytically independent. 2010 AMS Subject Classification: 13A30, 13B22, 13A15.
RELATION BETWEEN MATHEMATICS AND LAW “AN ANALYTICAL STUDY”
Authors: Patel Dr. Shriram
Published: June 2024

Law is rules of human activities it is the novel code of conduct to be followed by every citizens and human being who are living in particular nation as country where particular law has application. Although there are some laws which has universal application beyond territory of particular nation or country the laws which has universal application are considered natural laws divine laws or equity laws. The laws of world regardless of its application is considered as science based of certain norms and rules. According to famous jurist John Salmond “Law is Science of civil law1”. Prof. Kelson the law is science of norms2. The nature of law is humanities law having distinct identity closely related to various branches of knowledge. The law is not confined merely to statue, Act, ordinances rules regulation but it is related to all sciences like political science, sociology, mathematics, chemistry and all other sciences. However during the 19th century period physical sciences, chemistry, physics, biology made marked progress by adhering inductive method to find out= exactitude causal relationship between the matter and the hypothesis. In 20thcentury, mathematics contributed to progressive evolution of law. The physical law of Newton gravity theory and evolution theory of Darwin were of this kind. The mathematics science has its influence of penalty as fine as well as providing pecuniary compensation to victim.
SEDITION LAWS IN INDIA: A CRITICAL REVIEW
Authors: Afreen Tehseen
Published: June 2024

The Unlawful Activities (Prevention) Act of 1967 (UAPA) evolved as an anti-terrorism statute that stops unlawful activities associations and people from engaging in unlawful activities while upholding India's integrity and sovereignty. It has been revised to serve the basic purpose of the act and to ensure its successful application. However, it violates and undermines a few basic human rights because the term “terrorist” has not been given an appropriate definition, creating a vacuum and a question about the authority for the grounds of an Individual's detention under the UAPA and ending up with a troublesome nature for citizens. The Unlawful Activities (Prevention) Act has been the subject of numerous petitions from people who claim that it breaches several key articles of the Indian Constitution. They are asking for the act's provisions to be declared unconstitutional. The jailed person must deal with serious consequences when their bail request is denied. There are many debates over its nature and incidents where many human rights activists were held for years without being tried in court. Laws like the UAPA are blatant violations of the constitutional guarantees of freedom that are necessary for democracy to flourish. These freedoms grant people the right to express themselves through rallies and protests and also permit the public to mobilize their thoughts, whether or not these choices are critical of the government. By reviving colonial policies intended to stifle freedom movements, this Amendment makes a retrograde. In the majority of circumstances, the Act makes actions that are motivated by ideology or association illegal. Therefore, an effort has been made to examine the 1967 Unlawful Activities (Prevention) Act through this paper.
IMPACT OF ARTIFICIAL INTELLIGENCE AND LAW
Authors: Kavya Menda
Published: June 2024

Artificial intelligence (AI) is a rapidly developing technology that has the potential to alter how people communicate and interact with one another in the workplace and other social and economic settings. It is based on data service industries and improves our lives by suggesting articles and breaking news and acting as a meeting reminder. AI has the power to alter how individuals interact with the internet, one another, and other socioeconomic institutions. The legal profession is also being transformed by AI, with paperwork and data management being replaced by software. The legal industry is experiencing rapid growth and technological advancement, with over 100,000 jobs facing a high risk of automation in the next twenty years. The legal profession has been revolutionizing with innovations such as typewriters, computers, libraries, online portals, fax machines, and emails. Given that the worldwide market for legal services is thought to function with a low level of digitalization, the moment is ideal for AI to begin working in the legal profession.
BIOSURFACTANTS FOR SUSTAINABLE SOIL MANAGEMENT
Authors: S. R Manasa , K Tilak , N Sushma , V. S Vidya
Published: June 2024

Biosurfactants, a diverse group of biologically-derived surface-active molecules, have garnered significant attention due wide applications and special properties. Produced by microorganisms, biosurfactants exhibit exceptional surface tension reduction, emulsification, and foaming abilities, surpassing their synthetic counterparts in several aspects. This abstract provides an overview of biosurfactants, their production and their diverse applications.
PROSPECT OF NANOTECHNOLOGY IN FOOD PACKAGING
Authors: Singh Richa
Published: June 2024

Nanotechnology is a revolutionary technology that has the power to transform our lives in countless ways. It’s potential to improve health, wealth, products, and food is immense. However, it is surprising that food nanopackaging, an area with immense possibilities, has not been explored to its full potential yet in the fields of nanoscience and food science. This chapter covers bio-based packaging technology with potential applications in the industry. The utilization of bio-based packaging as an alternative to conventional packaging has emerged as an effective solution to mitigate the environmental hazards posed by non-degradable plastic polymers. Bio-based packaging offers the ability to reduce waste, extend the shelf life of products, and improve their quality. Further, enhancing its properties, nanomaterials can be employed to improve the packaging’s barrier properties, mechanical strength, flexibility, and stability. Its implementation could enhance food quality, safety, and sustainability.
KOKUM AN UNDERUTILIZED FRUIT AND ITS THERAPEUTIC BENEFITS: A REVIEW ON ITS NUTRITIONAL ASPECT
Authors: Mathur Shubhi
Published: June 2024

Kokum, is an underutilized fruit scientifically named as Garcinia indica Choisy consisting of Nutraceutical properties benefitting to ailments due its abundance in phytoconstituents such as Garcinol, HCA and anthocyanin. These are typically located in India’s western ghats and harvested in the summer season between April and May, belonging to Guttiferae family it is used widely from pharmaceutical industries using it as a drug for cure whereas confectionary industry producing wine to skincare products. Though kokum holds its place in Ayurveda by using its sources due to presence of several bioactive substances like xanthones, flavonoids and phenolic acids is being fully utilized to treat various disorders. Studies are demonstrating this substance mode of action against tumor cells including anti-histamine and anti-inflammatory effects. Mainly kokum rind part is utilized majorly which not only possess fat reducing properties curing obesity but also prevents the action of the enzyme citrate which transforms carbs into fats.
ROLE OF NUTRITION FOR INJURY REHABILITATION IN ATHLETES AND FOR BETTER PERFORMANCE AFTER RECOVERY: A REVIEW
Authors: Sharma Akshi , Sharma Dhananjay
Published: June 2024

The process of restoring to normal life after injury, by proper training and therapy is known as rehabilitation. There is no sports participation without the risk of injuries and fear of injury affects the performance of athletes. There are various types of sports injuries that are categorized under muscle, joint, and bone injuries. These injuries occur because of inadequate nutrition, improper techniques, use of improper equipment, and because of not wearing protective equipment. After having an injury, it is important to recover quickly and to enter the game as soon as possible. The role of nutrition during rehabilitation is very important and providing an adequate amount of nutrition is mandatory as micro and macro nutrients which are present in an athlete’s diet can speed up the recovery time if consumed in proper amounts. Strain, sprain, dislocation, fractures, knockout, punch syndrome, wrestler ear weightlifter blackout, etc are some common sports injuries. In this review, we have focused on the role of various micro and macronutrients and certain supplements which are required for injury recovery. Intake of a diet that is rich in protein, carbohydrates, fats, antioxidants, fiber, omega-3 fatty acids, phytochemicals, and vitamins C and D is very beneficial as it increases the recovery rate. Probiotics, dietary fiber, and prebiotics decrease the side effects caused by antibiotics and are also responsible for increasing the absorption of protein. Phytochemicals are found in fruits and its consumption through whole food is considered beneficial as compared to supplements. Phytochemicals reduce muscle soreness and inflammation and increase the recovery time. During rehabilitation, maintaining energy balance is very important as a negative energy balance can reduce muscle mass. Intake of collagen, with gelatin and vitamin C, helps in joint and tendon injury recovery. It also reduces knee pain and increases the thickness of the cartilage. Vitamin D can be received from sunlight and can also be consumed through supplements. Intake of vitamin D and calcium supplements increases bone density.
FOOD STORAGE AND PRESERVATION
Authors: Renu Shrestha Dr. , Deepa Joshi Dr.
Published: June 2024

The practice of food preservation is not new to human civilization. From the ancient time, leaves, branches of tree, bamboo have been utilized to keep the food items fresh and easy to transport. Now a days, researchers discovered many technologies to upkeep the shelf life of food items, but emphasis has been given to those techniques which not only enhance the shelf life of the product, but also lessen the nutrient loss and organoleptic properties loss. This chapter includes all the conventional and modern technologies, which are being utilized for this purpose.
A REVIEW ON AQUATIC WEEDS AND THEIR MANAGEMENT
Authors: P Sedyaaw , J. M Koli , Sharangdher S. T. , Pathan D. I.
Published: June 2024

When aquatic weeds grow too much, they pose a threat to fish farming. An essential component of pond management is weed control. Among the 160 aquatic weeds in India, the following are of important: Salvinia molesta, Ceratophyllum demersum, Chara spp., Hydrilla verticillata, Eichhornia crrassipes, Typha angustata, Nelumbo nucifera, Nitelias, Ipomoea aquatica, Alternanthera philoxeroides, Vallisneria spiralis. Aquatic weeds are rapidly expanding in several irrigation and hydropower projects across the nation, including the Kakki and Idikki reservoirs in Kerala, the Tungabhadra project in Karnataka, and the Nagarjuna Sagar project in Andhra Pradesh. Weeds significantly increase evapotranspiration rates compared to open surface rates, which results in significant water loss. Eutrophication caused by water hyacinth renders water unsuitable and reduces water flow, in addition to various health-related issues. Biological, chemical, and physical strategies can all be used to control aquatic weeds. Aquatic weeds can be stopped from spreading or eliminated using a number of common control methods. Physical remedies work best for small-scale infestations, but they are expensive and prone to regrowth when used on big water bodies. Aquatic weeds have long been subject to chemical treatment, however this practise is not common in India. Herbicide control of tiny infestations has frequently been quite successful, but it significantly depends on trained operators who keep a close eye out for the appearance of regrowth or seedlings over a lengthy period of time. The amount of nutrients released into water in recent decades has significantly increased from home and industrial sources as well as from land where fertilisers are applied or where clearing has increased run-off. Neochetina spp. and Cyrtobagaus salvinae, exotic weevils, have been used successfully to manage water hyacinth and water fern in several parts of India, but suitable bio- agents are not yet available for several additional aquatic weeds. With varied degrees of success, some submerged weed, particularly Hydrilla species, have been controlled using some kinds of herbivorous fish, including Tilapia spp. and Ctenopharyndon idella. This essay discusses the issues with aquatic weeds in India and the attempts taken thus far to manage them using a variety of techniques.
STUMP APPENDICITIS; IT’S RARE, BUT STILL THERE
Authors: Chaudhary Rajesh , Baharti Ramesh , Bhatia Arvind , Shukla Ankit , Kumar Munish , Rana Maninder
Published: June 2024

Acute appendicitis is the most common surgical emergency worldwide so, emergency appendectomy is the most performed emergency surgery throughout the world. Intestinal obstruction, intraabdominal collection, faecal fistula formation and incisional hernias are the complications of appendectomy. Stump appendicitis is one of the rarest complications of appendectomy. World over, only 132 cases have been reported so far. Since the patients have undergone appendectomy, Stump appendicitis is last of any physician’s initial diagnoses, leading to mismanagement of such patients. The diagnosis is usually based on the clinical examination which is like those in acute appendicitis but since there is the history of appendectomy, usually another diagnosis is considered first. Ultrasound of the abdomen can pick up Stump appendicitis, but still undiagnosed cases will require the CECT of abdomen for diagnosis. This difficulty and delay in diagnoses may lead to serious complications like perforation of the Caecum and generalised peritonitis. Completion Appendectomy, whether open or laparoscopic, is the treatment of choice. We present the case of a 31-year-old female patient who presented to ED with a RIF pain after 8 months of emergency Appendectomy. She had a history of similar complaints in the past and was previously treated for UTI, 3 months ago. This time she again presented with the signs and symptoms of acute appendicitis and subsequently was diagnosed as stump appendicitis on USG Abdomen. Completion Appendectomy was done. To manage stump appendicitis high index of suspicion, good clinical acumen and surgical expertise is required. Although the patients can be managed conservatively with antibiotics, Completion Appendectomy is the treatment of choice.
SYSTEMATIC REVIEW ON WEARABLE GADGETS IN HEALTHCARE MANAGEMENT
Authors: Gurugubelli Simhachalam , Pydi Swetha
Published: June 2024

This chapter reflects upon the impact that wearables have on modern medicine and fitness especially tracking variables of aerobic fitness.
PLASTINATION- ADVANCED TECHNIQUE TO PRESERVE SPECIMENS IN MEDICAL AND DENTAL COLLEGES
Authors: Rajan Dr. T. , Vinothini Dr. G. , Nagarajan Dr. Prithiviraj
Published: June 2024

n addition to its educational significance, this chapter highlights the practical advantages of plastinated specimens in medical and dental colleges. Plastination offers a cost-effective and safe alternative to traditional preservation methods, reducing the need for toxic fixatives and frequent maintenance. With their long-lasting properties, plastinated specimens provide a valuable resource for long-term research and histologic examination. Furthermore, the chapter discusses the limitations and challenges associated with plastination, including the technique's complexity and the need for specialized equipment and dedicated staff. Despite these challenges, plastination remains a transformative technique that continues to shape the future of anatomical teaching and research in medical and dental education.
MIGRAINE AND THE ENDOCANNABINOID SYSTEM: A STORMY RELATIONSHIP
Authors: Pala Daniele , Deidda Arianna , Cherchi Alessandra , Erminia Stochino Maria , Pistis Marco
Published: June 2024

Migraine is a neurological disorder with high incidence characterized by peripheral and central sensitization. The trigemino-vascular system is implicated in the genesis of the migraine attack. CGRP is one of the main determinants of the migraine pain. CGRP-targeting drugs like anti-CGRP monoclonal antibodies (anti-CGRP and anti-CGRP-receptor monoclonal antibodies) and CGRP-receptor antagonists named “gepants” are effective and safe drugs recently introduced into clinical practice. The endocannabinoid system is a lipid-based neurotransmitter complex that has been linked to migraine. The CB1 receptor is localized in the presynaptic synapses of the trigeminal terminals and is activated by the endocannabinoid anandamide. It acts as a negative regulator of the CGRP release. Anandamide has been found in reduced amounts in subjects suffering from migraine. This review will summarize the evidence in the literature regarding the relationship between migraine and the endocannabinoid system, particularly the clinical data.
TO DO OR NOT TO DO: ORAL CANCER DIAGNOSTIC MODALITIES
Authors: Pathak Dr. Aparna , Kaur Dr. Geetptriya , Handa Dr. Tanvi , Trimukhe Dr. Akshay Chandrakant
Published: June 2024

Oral cancer is one of the most common head and neck cancers, and the overall 5-year survival rate is less than 50%. Oral squamous cell carcinoma is the most common type of oral malignancy. Various diagnostic techniques have been developed for early diagnosis of oral cancer. The wide spectrum of diagnostic modalities used for early detection of oral cancer include common diagnostic techniques, new diagnostic techniques under development, and advanced diagnostic techniques. To date, intraoral and extraoral examination is still the standard method for the detection of oral cancer. The most common diagnostic techniques involved in oral cancer examination are visual examination, biopsy and histopathology report, vital staining, oral cytology, and optical imaging. The main new diagnostic methods under development include DNA Methylation Biomarkers, mRNA biomarkers, and protein biomarkers. The discovery of biomarkers in biological fluids such as blood, urine, and saliva provides significant hope for early diagnosis. The recently developing advanced diagnostic techniques include Artificial Intelligence, Oral Fluid Biosensor, and Lab – on – Chip. Considering the scale of oral cancer research, most of the diagnostic modalities are available commercially. Therefore, future tools such as AI-based technology should be explored to improve the effectiveness of oral cancer diagnosis.
UNANI SYSTEM OF MEDICINE-GLOBAL STATUS AND CAREER PROSPECTS
Authors: Hasan Lari Dr. Qamrul , Akhtar Dr. Sana , Khan Dr. Mohammad Shamim
Published: June 2024

The Unani medical system that originated in the Greece was later on taken up by the Romans. Thereafter, it reached land of the Arabs and from there to Central Asia and parts of Europe during the Middle Ages. It reached to India from Arab and Iran and developed into comprehensive medical system. In order to promote and propagate Unani system of medicine worldwide, various efforts have been made and strategies have been formulated by Government of India and the International organizations such as World Health Organization. Ministry of Ayush and WHO have given recognition to this system and are doing their best in the upliftment of system. Although Unani medicine is popular among the masses of Islamic Republic of Iran, South Africa, and some other countries but it has a special status in Indian subcontinent. With a vast, functional network of institutions of higher learning, medical facilities, and research and development, India is currently leading the world in the field of n Unani Medicine. Few decades earlier, due to lack of awareness and information access, the Unani graduates were confined to the field of private practice only. Rapid expansion of healthcare industry, opening up of new colleges, institutions, hospitals, research unit has open the path of utilisation of Unani scholars. Various career opportunities available to Unani graduates in general or with specialisation can be classified as academics, civil services, hospital and health management, Research and Development, Drug Manufacturing Unit, Medical tourism, Medical informatics etc. Through qualifying TCAM exam, they can get license to practice in UAE. An attempt has been made in this chapter to explore the global status of Unani system of Medicine and career opportunities available for Unani scholars.
A STUDY ON KNOWLEDGE, ATTITUDE AND PRACTICES TOWARDS IRON DEFICIENCY ANEMIA AMONG ADOLESCENT GIRLS (10-19 YEARS) OF HAPUR, UTTAR PRADESH- A CROSS-SECTIONAL STUDY
Authors: Agarwal Charu , Agarwal Shalini
Published: June 2024

Iron deficiency anemia (IDA) is a significant public health concern, particularly among adolescent girls, due to their increased iron demands during the rapid growth and development phase. The present study aimed to assess the knowledge, attitudes, and practices related to iron deficiency anemia among adolescent girls aged 10-19 years in the Hapur district of Uttar Pradesh. This cross-sectional study was conducted which involved a representative sample of 50 adolescent girls (10-19 yrs) from various educational institutions and community settings. A structured questionnaire was designed to gather data on the participants' knowledge about iron deficiency anemia.The study also sought to understand the attitudes of the participants towards anemia and their perception of the importance of iron-rich diets and iron supplementation. Additionally, the practices related to dietary habits, consumption of iron supplements (if any), and awareness of available healthcare services for anemia were assessed. The findings reveal a concerning lack of awareness regarding iron deficiency anemia and its potential health implications among the target population. Attitude assessment further highlighted the challenges in adopting iron-rich dietary practices.The study revealed suboptimal dietary practices, with a considerable proportion of adolescent girls consuming diets lacking in iron-rich foods contributing to the prevalence of anemia. Therefore, it is necessary to address knowledge gaps, misconceptions, and dietary practices related to iron deficiency anemia among adolescent girls in Hapur, Uttar Pradesh.
CHROMOSOMAL ABERRATIONS AND FERTILITY – A REVIEW
Authors: Shubham Mr. , Kumar Aman , Raina Arun
Published: June 2024

Genetic disorders are the disorder which are caused due to the mutation or any change in the genome of individual. Genetic disorders are majorly divided into three groups : single gene disorders, chromosomal disorders and/ or multifactorial disorders. Single gene disorders or we can say that the mendelian disorders are occurs by any change in the DNA sequence of a gene like autosomal dominant, autosomal recessive, sex linked dominant, sex linked recessive. Chromosomal disorders are occurs because of chromosomal aberrations, occurs by numerically and/or structural changes. Molecular and cytogenetic techniques are widely used to examine the genetic changes that causes disorders.
GHRITHA-AN ELIXIR IN VISHA CHIKITSA
Authors: Raj Dr. Sheethal , P. K Dr. Athulya
Published: June 2024

Every moment, human beings are exposed to a wide variety of poisoning. It is imperative to have an advancement in science to protect our body from the harmful effect of poison. Hridaya is the organ which is primarily affected by Visha which results in death of an individual. Ghritha is considered as an elixir in Visha chikitsa as it is Vishahara, Ojo vardhaka, Vatapittahara and it does Hridayavarana and increases the longevity of life.
SYNTHESIS, PROPERTIES AND APPLICATIONS OF DENDRIMERS IN CHEMISTRY, MATERIALS SCIENCE AND NANOTECHNOLOGY
Authors: Khan Aashif , Kumar Gupta Ajay , Kumar Jain Sanmati
Published: June 2024

Dendrimers are monodispersing, well-defined, and uniform macromolecules with symmetrical branched units constructed around a small molecule or a linear polymer core. They have a core that is typically symmetric, an outer shell, and an inner shell. It discusses the divergent and convergent methods of synthesis, explaining their advantages and challenges. The concept of dendrimers, such as polyamidoamine (PAMAM), Polypropylenimine (PPI), and L-lysine-based dendrimers, showcases their distinct characteristics and applications ranging from drug delivery, gene therapy, and imaging to sensing, catalysis, and optoelectronics, underscoring the versatility of dendrimers. Dendrimers could be a wonderful choice in pharmaceuticals because of their diverse abilities and various applications.
NANOMATERIAL CHARACTERIZATION TECHNIQUES
Authors: Singh Arpita , A. Chavan Vilas , P Ariya , Udaynadh BVSS , Adithi Erra
Published: June 2024

What nanotechnology is going to do? It is predicted that nanotechnology will alter how we live as it has already influenced the modern technology. Nanomaterials have sparked significant interest across many scientific and industrial areas because of their distinctive features and applications. Accurate characterization of nanoparticles is essential to comprehending their structure, properties and behavior as nanotechnology develops. Any technology that works with materials at the nanoscale and has different biological, chemical, and physical properties from those of the bulk is referred to as nanotechnology. The fundamentals of instrumentation and their uses in the characterization of nanomaterials will be covered in this chapter. Among the various nanotechnologies, nanomaterials are characterized with instrumentations including dynamic light scattering (DLS), X-ray photoelectron spectroscopy (XPS),scanning electron microscope (SEM), secondary mass ion spectrometry (SIMS), transmission electron microscope (TEM), high resolution transmission electron microscopy (HRTEM), atomic force microscope (AFM), X-ray Diffraction (XRD) and Raman micro spectroscopy (Micro-Raman).In addition to imaging techniques, spectroscopic methods are crucial for understanding nanomaterial properties at the atomic and molecular levels. The spectroscopic techniques provide valuable insights into the chemical composition, crystal structure, and functional groups present in nanomaterials. The chapter concludes by highlighting the complementary nature of various nanomaterial characterization techniques and the importance of employing multiple methods for comprehensive material analysis. As nanotechnology continues to evolve, advancing these characterization techniques is vital for realizing the full potential of nanomaterials in diverse fields, including medicine, electronics, energy, and environmental applications.
APPLICATIONS OF NANOMATERIALS IN CHEMICAL INDUSTRY
Authors: Nageswararao P. V. , A Chavan Vilas , P Arya , Adithi Erra , Prasanthi M. , Udaynadh BVSS
Published: June 2024

The conventional chemical industry has grown into a largely mature sector with a sizable amount of common goods created using tried-and-true methods. Therefore, it is more likely that specialty chemicals, novel functionalities derived from new processing techniques, and new microstructure control procedures will lead to new product and market prospects. It is well known that a material's molecular structure and microstructure play major roles in determining its properties. In order to make new discoveries, it is essential to regulate structures at the Nano- and micro-scales. The controlled manipulation of nanomaterials with at least one dimension below 100 nm is referred to as nanotechnology in this article. The production of goods and chemical compounds by the chemical industry was expensive and required more energy. For the generation of industrial energy on a big scale, these materials are inadequate. Modern chemical methods are no longer employed as a result. Nowadays, one of the greatest approaches for creating chemical compounds from nanoparticles is biological procedures employing a chemical approach. As a result of its small size, nanomaterials have several unique characteristics. Catalysts, selective adsorbents, protection, chemical sensors, water purification, drug delivery, coatings, and the production of nanofibers and other biopharmaceuticals and medical devices are the main applications in the chemical industries, and they all play significant roles in fostering the growth of the sector.
BEYOND THE SURFACE: EXPLORING THE GENETIC LANDSCAPE OF FUNGI FOR MEDICAL SOLUTIONS
Authors: Maheswary Dr. D. , Ramakrishnan Varshni , Gopinathan Dr. Anusha , Leela Dr. K.V.
Published: June 2024

Fungal infections are one of the leading causes of morbidity and mortality in the world. In recent years, the emergence of drug-resistant strains of Candida albicans poses a significant threat if infection control practices are not properly implemented alongside therapy.1 Moreover, understanding the molecular mechanisms underlying fungal pathogenesis and host-fungus interactions is crucial for developing effective strategies to combat fungal infections and mitigate their impact on human health and agriculture.1 In this chapter , we will explore the fungal genomics and fungi, providing insights into their evolutionary history and adaptation to different environments, paving the way for the development of more effective antifungal treatments.
FUTURISTIC TRENDS IN MEDICAL SCIENCES
Authors: K Dr. Kadiervel
Published: June 2024

This chapter delves into the forefront of medical innovation, covering Precision Medicine, Nanotechnology, CRISPR Technology, and Genomic Medicine. These cutting-edge fields collectively represent the vanguard of healthcare, promising to redefine diagnostics, treatment, and our understanding of the intricacies of human biology. The exploration begins with Precision Medicine, a paradigm shift in healthcare that tailors treatments to the individual's genetic makeup, environment, and lifestyle. By leveraging advanced genomic sequencing technologies, Precision Medicine empowers clinicians to devise targeted therapies with heightened efficacy and diminished side effects. The chapter examines the implications, challenges, and potential transformative impact of this personalized approach on healthcare. Nanotechnology takes center stage as the discussion unfolds, demonstrating its potential to revolutionize drug delivery. Engineered nanoparticles, scrutinized within the chapter, showcase the ability to transport drugs directly to targeted cells or tissues, thereby enhancing efficacy and minimizing adverse effects. Nanosensors and nanobots, designed for early disease detection and internal monitoring, add an exciting dimension to the evolving landscape of healthcare. CRISPR Technology emerges as a revolutionary force, allowing precise modification of genes. Explored within the chapter is the potential of CRISPR in correcting genetic defects, combating hereditary diseases, and even reshaping the understanding of human evolution. Ethical considerations surrounding gene editing and the societal implications of wielding such unprecedented genetic control are also addressed. Genomic Medicine, with its focus on deciphering the complete set of genes within an individual, forms another critical aspect of this exploration. The chapter scrutinizes how decoding the human genome has unlocked the secrets of DNA, paving the way for personalized treatments and more accurate diagnostic tools. Pharmacogenomics, a subset of Genomic Medicine, is discussed for its role in tailoring medication based on an individual's genetic profile. In conclusion, this chapter illuminates the transformative potential of Precision Medicine, Nanotechnology, CRISPR Technology, and Genomic Medicine in shaping the trajectory of medical sciences. It underscores the necessity for ongoing research, ethical considerations, and collaborative efforts to harness the full potential of these innovations, ensuring they contribute meaningfully to the advancement of healthcare.
INTERPRETATION OF ISCHEMIC HEART DISEASE IN TERMS OF AYURVEDIC SIX STAGES OF PATHOGENESIS & THERAPEUTIC INTERVENTION (SHAT KRIYAKALA)
Authors: Waghe Dr. Subhash
Published: June 2024

The death due to ischemic heart disease is increasing in Indian population at an alarming rate and accounts for around 15-20% of all deaths. The number of factors play role in the development of ischemic heart diseases but over consumption of oily fatty food and unhealthy lifestyle (mithya ahar vihar) with mental stress are the important basic factors enumerated by both the science. Shatkriya Kala is a unique pathological concept in Ayurveda developed with aim of treating the diseases at various stages of pathogenesis. Ancient Ayurvedic acharyas had stated 6 such stages of therapeutic intervention with reference to six stages of pathogenesis namely sanchaya, prakopa, prasara, sthansanshraya, vyakti and bheda. If disease is treated in early stages, it does not lead to complications. Hence, it is essential to apply the Ayurvedic concept of pathogenesis like ‘Shat Kriyakala’ to ischemic heart disease so as to study it from Ayurvedic pathological point of view and to evolve a strategy to deal with it, based on the Ayurvedokta principles of treatment particularly in terms of shatkriyakalas. The study of ischemic heart disease with reference to Shat Kriyakala, showed that the pathogenesis of ischemic heart disease can very well be arranged in Ayurvedokta six stages of Shat Kriyakala and treatment could be framed as per different stages. With the help of modern investigations, these six stages could be confirmed.