bluuebunny/crossref_metadata_2025 huggingface dataset:
The effects of upper body blood flow restriction training on muscles located proximal to the applied occlusive pressure: A systematic review with meta-analysis
Authors: Pavlou Kyriakos , Korakakis Vasileios , Whiteley Rod , Karagiannis Christos , Ploutarchou George , Savva Christos
Published: March 2023

Background

Blood flow restriction combined with low load resistance training (LL-BFRT) is associated with increases in upper limb muscle strength and size. The effect of LL-BFRT on upper limb muscles located proximal to the BFR cuff application is unclear.

Objective

The aim of this systematic review was to evaluate the effect of LL-BFRT compared to low load, or high load resistance training (LL-RT, HL-RT) on musculature located proximal to cuff placement.

Methods

Six electronic databases were searched for randomized controlled trials (RCTs). Two reviewers independently evaluated the risk of bias using the PEDro scale. We performed a meta-analysis using a random effects model, or calculated mean differences (fixed-effect) where appropriate. We judged the certainty of evidence using the GRADE approach.

Results

The systematic literature searched yielded 346 articles, of which 9 studies were eligible. The evidence for all outcomes was of very low to low certainty. Across all comparisons, a significant increase in bench press and shoulder flexion strength was found in favor of LL-BFRT compared to LL-RT, and in shoulder lean mass and pectoralis major thickness in favor of the LL-BFRT compared to LL-RT and HL-RT, respectively. No significant differences were found between LL-BFRT and HL-RT in muscle strength.

Conclusion

With low certainty LL-BFRT appears to be equally effective to HL-RT for improving muscle strength in upper body muscles located proximal to the BFR stimulus in healthy adults. Furthermore, LL-BFRT may induce muscle size increase, but these adaptations are not superior to LL-RT or HL-RT.
Trains and Constrains: Re-Examining the Griersonian Documentary Influence upon David Lean’s Brief Encounter (1945)
Authors: Moore Emily
Published: March 2023

Early British documentary cinema, pioneered by John Grierson, undeniably had a heavy influence on later wartime-era cinema. One such film is David Lean’s beloved Brief Encounter. Lean’s utilization of a first-person, omnipresent narrative structure mirrors the philosophy behind these earlier documentary films. By first providing an overview of the history of documentary film, Lean’s depiction of the banality of middle England is then re-examined through the lens of Laura and Alec’s affair. Particular focus is placed upon his depiction of class, empire, and female voices, which are compared and contrasted to these aforementioned British documentaries.
Dossier Introduction: Contemporary Horror Cinema
Authors: Cottrel Adam , Michael Charlie , Rusnak Stacy
Published: March 2023

The five essays compiled in this dossier address issues of representation in classic and contemporary horror cinema. Students from the Film program at Georgia Gwinnett College (Lawrenceville, Georgia) consider films by Alfred Hitchcock, Jordan Peele, Wes Craven, Pedro Almodovar, and others. In this brief introduction, the three faculty editors of the dossier discuss the theoretical and cultural stakes of the essays to follow.
Interview with Daniel Scarpati, Filmmaker and Author of Gofers
Authors: Underwood Gray
Published: March 2023

This is an interview with New York-based filmmaker/author Daniel Scarpati about his experiences working on set in various capacities and his writing/self-publishing process in creating Gofers, a guide to life on a film set and beyond for aspiring filmmakers and PAs.
Analysing the groundwater level and its determinants in a drained peatland forest: a case study in South Lapland, Finland
Authors: Hiltunen Oiva , Hallikainen Ville , Palander Teijo
Published: March 2023

In southern Lapland, 70% of drained peatland forests have a peat layer thickness of less than one metre. On these sites, the question is how the subsoil under the peat affects groundwater level and thus timber harvesting. The aim of this study was to investigate the effect of the peat layer (<1 m) and subsoil on the groundwater level and its variation during the growing season (non-frost) by modelling the factors affecting water level. In sandy soils, the groundwater level rose by 20 cm when the peat layer thickness increased from 20 to 70 cm. In silty soils the effect of the peat thickness on groundwater remained minor. When the subsoil was sand or coarser, the groundwater level was usually deeper than when it was silty or finer. The effect of stand volume (m–3 ha–1) on the groundwater level was rather weak albeit significant. The model explained a significant part of the groundwater surface variation, with a marginal coefficient of determination (R2) of 68%. It seems that the rutting of roads could be avoided in late summer if the precipitation is remarkably lower during that period, or if the subsoil is sandy with thin peat layer on top of it. Because the groundwater level affects the load-bearing capacity of timber-harvesting machinery, it is important to study this issue in more detail in the future.
Infliximab for Steroid-Refractory Immune Checkpoint Inhibitor-Induced Acute Pancreatitis
Authors: Townsend Matthew J. , Hodi F. Stephen , Grover Shilpa
Published: March 2023

Acute pancreatitis is an infrequent but clinically significant complication of immune checkpoint inhibitor (ICI) therapy. Guidelines recommend high-dose steroids and withdrawal of ICI in patients with severe ICI-induced pancreatitis. Management of steroid-refractory ICI pancreatitis is unclear. Infliximab is used to treat select extrapancreatic immune-related adverse events, but its role in ICI pancreatitis remains undefined. To our knowledge, we describe the first case of ICI pancreatitis successfully treated with infliximab after inadequate steroid response (recurrent pancreatitis on multiple attempted steroid tapers). Infliximab may be a viable treatment of steroid-refractory ICI pancreatitis. Further study of its potential effectiveness may improve guideline-directed care.
Drogas en la adolescencia. Modelo descriptivo de tipo cognitivo y neuropsicológico
Authors: Erazo Santander Oscar Armando
Published: March 2023

Introducción: La drogadicción es una pandemia que afecta a 324 millones de consumidores y que en Colombia un 63% de estudiantes informan haber consumido algún tipo de droga, los gobiernos en su afán de intervenir la problemática han buscado reducir la oferta con resultados negativos y de comprender la demanda con tesis neuropsicológicas que explican el mantenimiento de la conducta y de buscar comprender que lleva a los sujetos a elegir y realizar la primera conducta de consumo. Ante esta última premisa el estudio busca identificar y describir las relaciones existentes entre factores cognitivos como la intencionalidad y las funciones ejecutivas de inhibición, planeación y toma de decisiones en los procesos de elección y realización de esta conducta en los adolescentes. Metodología: En una muestra de 80 estudiantes se realizó un estudio cuantitativo de tipo descriptivo y correlacional al cual se le aplico el Emiud para evaluar la intención de consumo, laberintos y torres para planeación, laberintos y stroop para inhibición y juego de carta de Iowa para toma de decisiones. Resultados: El 51% de estudiantes informa no tener seguridad de no consumir una droga y un 14% informar tener la intención de consumir, además cuando la intención es positiva se acompaña de actitudes, norma subjetiva y control conductual también positivas, las cuales se correlacionan de forma negativa con la planeación, inhibición y toma de decisiones. Discusión: Los estudiantes con intención de consumir una droga presentan una inhibición con tendencia impulsiva y automática, planeación de corto plazo y una toma de decisiones con riesgo.
iolencia de pareja: propuestas de atención en aislamiento por COVID-19
Authors: Quiroz Molinares Nathalia , Medina Sarmiento Wendy Isabel
Published: March 2023

La violencia de pareja es un problema de salud pública, así como una violación a los derechos humanos. Este tipo de violencia incluye actos de abuso físico, sexual, verbal y emocional cometidos dentro del marco de una relación afectiva (Ministerio de Salud Pública, 2019). Debido a las crisis y los momentos de incertidumbre desatados por la actual emergencia sanitaria causada por el SARS-COV-19, se han desencadenado un importante incremento en los casos de violencia de pareja en todo el mundo, así lo confirman algunas cifras disponibles en el informe expuesto por Ruiz y Pastor (2020), en donde mencionan que las líneas de ayuda han registrado un aumento del 60% en México, el 40% en Australia, el 30% en Chipre y el 20% en los Estados Unidos.
Differences Between Sexes in Psychopathological Variables among Adolescent Victims of Dating Violence
Authors: Rey Anacona César Armando , Martínez Gómez Jorge Arturo
Published: March 2023

Este estudio descriptivo comparativo tuvo como objetivo examinar si existían diferencias por sexo con respecto a un conjunto de variables psicopatológicas y otras dificultades, entre adolescentes víctimas de violencia en el noviazgo (VN). Participaron 757 adolescentes entre 12 y 19 años de edad, el 59% mujeres, vinculados a 15 instituciones de educación media de dos ciudades intermedias de Colombia. Se utilizó la versión española del Conflict in Adolescent Dating Relationships Inventory (CADRI), el Sistema de Evaluación de la Conducta de Niños y Adolescentes -versión de auto informe- (BASC-S3), la Lista de Síntomas SCL-90-R y un cuestionario de auto-informe de variables psicológicas. Los va-rones reportaron haber recibido una frecuencia mayor de malos tratos de tipo relacional y físico. Sin embargo, las mujeres evidenciaron una frecuencia signi-ficativamente mayor de síntomas psicopatológicos, un mayor desajuste clínico y personal, y malas relaciones con pares y familiares, lo cual indica que las mujeres víctimas de esta forma de violencia presentan más dificultades, aspecto que debería ser considerado en las campañas prevención e intervención de esta problemática.
Revisión sistemática de las aplicaciones de la escala CS-DS Chronic Self Destructiveness Scale, 1985-2019
Authors: Higuita Gutiérrez Luis Felipe , Úsuga Úsuga Franky Alberto , Cardona Arias Jaiberth Antonio
Published: March 2023

Introducción: La escala CS-DS (Chronic Self-Destructiveness Scale) fue diseñada y validada en 1985 y a la fecha no se conocen sus aplicaciones en estudios investigativos. Objetivo: Analizar los usos de la escala CS-DS mediante una revisión sistemática de la literatura y comparar los puntajes de autodestructividad indirecta en diferentes grupos poblacionales en el periodo 1985-2019. Materiales y métodos: Revisión sistemática en cinco bases datos multidisciplinarias con tres estrategias de búsqueda siguiendo las recomendaciones de Cochrane, las fases de la guía PRISMA y los criterios de la guía MOOSE. La selección de los estudios y la extracción de las variables se realizó por dos investigadores garantizando exhaustividad y reproducibilidad. Se evaluó la calidad metodológica y se realizó metanálisis de medidas indirectas por tipo de población estudiada, metanálisis de efectos aleatorios para diferencia de medias según el sexo y meta-regresión por dimensiones de la escala. Resultados: Se incluyeron 23 estudios con 6.382 individuos. La menor autodestructividad se halló en población sana y con psoriasis, la mayor en drogadicción, seguido de intento suicida, delincuencia, ansiedad o depresión y esquizofrenia. En población sana no se hallaron diferencias según el sexo y en las personas con intento suicida se halló mayor autodestructividad en los hombres en las dimensiones de negligencia personal y social, falta de planificación e impotencia y pasividad frente a los problemas. Conclusión: La escala CS-DS ha sido aplicada básicamente en Estados Unidos y Polonia, en diferentes poblaciones de personas sanas y enfermas. CS-DS demuestra capacidad discriminante para perfilar la autodestructividad en diferentes poblaciones, principalmente con afectaciones mentales, al tiempo que sus dimensiones presentan un perfil diferencial por sexo.
Effect of Storage of Yellow Pigment from Halophilic Bacillus clausii J1G-0%B on Antioxidant Activity
Authors: Arum Galuh Dwi , Asy'ari Mukhammad , Mulyani Nies Suci
Published: March 2023

Oxidative stress is a state of excess free radicals in the body, which results in increased oxidation processes in the body’s cells and causes damage. In previous studies, one way to neutralize this situation was found, namely with halophilic bacteria. Halophilic bacteria can live at a salt content of 2% to 30%. These bacteria can produce various kinds of pigments for self-defense from extreme environments, which function as immunomodulatory compounds and have antioxidant activity. The antioxidant activity of the yellow pigment halophilic bacteria Bacillus clausii J1G-0%B using the DPPH method showed that the effect of light and air on antioxidant activity was 17.88% inhibition in the crude extract and 14.24% inhibition at 1600 ppm. Antioxidant activity decreased by 17.13% under the influence of air, 1.89% under the influence of light, and 28.58% under the influence of air and light. FTIR analysis under the influence of air experienced a decrease in the peak of the CO carbonyl group of 1739.29 cm-1 and an increase in the alkane C-H group of 1369.52 cm-1, while under the influence of light and open conditions, the carbonyl CO group experienced an increase of 1739.50 cm-1 and 1739.46 cm-1 and the increase in alkane C-H groups 1371.41 cm-1 and 1369.53 cm- 1.
Synthesis of Lead Oxide Using the Oxidizing Agent (NH4)2S2O8 with Variaous Amounts of NaOH for Decolorization of Remazol Black B Solution
Authors: Anggita Meiske Erdinarini , Haris Abdul , Widodo Didik Setiyo
Published: March 2023

In this study, the lead oxide has been successfully synthesized using oxidizing agents (NH4)2S2O8 and applied to decolorize the Remazole Black B (RBB) solution. Lead oxide was synthesized by the batch method through the mechanism of reduction-oxidation and characterized using SEM-EDX and XRD. Decolorizing RBB solution was performed using a modified Fenton method. This study aims to determine the optimum performance of RBB decolorization from lead oxide. The results showed that the crystal formed contains Pb and O. Pb oxide obtained was α-PBO2 with the orthorhombic crystal system. Based on characterization, the lead oxide obtained has a surface morphology of coral flowers-like. Synthesis utilizing equilibrium composition (1:2) and a drying temperature of 100°C yielded Pb oxide, which has a better potential as a modifier in RBB decolorization with a decolorization percentage of 80.07%. The process was then carried out for advanced synthesis less and excess of molar variations. The ratio of lead oxide: NaOH (1:4) showed optimum performance in decolorizing RBB with a decolorization percentage of 80.07 %.
ASUPAN VITAMIN D, KALSIUM DAN AKTIVITAS FISIK KAITANNYA DENGAN GANGGUAN SIKLUS MENSTRUASI PADA MAHASISWI
Authors: Mutia Miladia Gita , Putriana Dittasari
Published: March 2023

Latar Belakang: Masalah kesehatan reproduksi yang sering terjadi salah satunya gangguan siklus menstruasi. Di Indonesia, sebanyak 35,5% mahasiswi yang terdapat di 59 perguruan tinggi mengalami gangguan tersebut.  Adapun faktor yang mempengaruhi seperti kurangnya asupan vitamin D, asupan kalsium, dan tingginya aktivitas fisik. Mahasiswa Fakultas Hukum Universitas Muhammadiyah Surakarta memiliki aktivitas yang sangat padat, sehingga dilakukan studi pendahuluan di fakultas tersebut.Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan asupan vitamin D, asupan kalsium, dan aktivitas fisik dengan gangguan siklus menstruasi pada mahasisiwi Fakultas Hukum Universitas Muhammadiyah Surakarta. Metode: Desain penelitian ini adalah observasional dengan pendekatan cross sectional yang melibatkan 73 mahasiswi Fakultas Hukum Universitas Muhammadiyah Surakarta usia 18-19 tahun, yang diambil dengan metode accidental sampling. Data asupan vitamin D dan kalsium diperoleh menggunakan Semi Quantitative Food Frequency Questionnaire (SQ-FFQ) selama satu bulan terakhir, data aktivitas fisik menggunakan International Physical Activity Questionnaire (IPAQ) selama satu minggu terakhir dan data gangguan siklus menstruasi menggunakan kuesioner siklus menstruasi melalui google form. Analisis data pada software SPSS menggunakan uji chi square.Hasil : Sebagian besar responden memiliki asupan vitamin D kurang (94,5%), asupan kalsium kurang (87,7%), aktifitas fisik berat (80,8%) dan gangguan siklus menstruasi (4,1%). Hasil uji analisis chi square tidak terdapat hubungan antara asupan vitamin D (p=0,631), asupan kalsium (p=0,597), dan aktifitas fisik (p=0,389) dengan gangguan siklus menstruasi.  Simpulan: Tidak terdapat hubungan asupan vitamin D, asupan kalsium, dan aktivitas fisik dengan gangguan siklus menstruasi (p>0,05). Diharapkan responden dapat meningkatkan asupan vitamin D dan kalsium yang cukup serta memperhatikan aktivitas fisik agar tidak berlebihan
„Biblioteka” – kilka refleksji z okazji 25-lecia nowej edycji czasopisma
Authors: Dąbrowicz Małgorzata , Jazdon Artur
Published: March 2023

W artykule zostały przedstawione historia i teraźniejszość „Biblioteki” – czasopisma naukowego wydawanego przez Bibliotekę Uniwersytecką w Poznaniu. Obecna edycja rocznika, publikowana od 1997 roku, jest kontynuacją czasopisma ukazującego się w latach 1960–1970. Z okazji 25-lecia nowej edycji „Biblioteki” podsumowano dotychczasowy dorobek czasopisma oraz wskazano współczesne wyzwania związane z jego dalszym rozwojem.
A Recently Discovered Folia from the 12th-century Apostolus Christinopolitanus
Authors: Voloshchenko Stanislav
Published: March 2023

One of the important Cyrillic medieval manuscripts from Kievan Rus is the Apostolus Christinopolitanus – a 12th-century codex which is now separated into two parts that are preserved (though some fragments have been lost) in Kyiv (Institute of Manuscript of V.I. Vernadskyi National Library of Ukraine, since 1927) and Lviv (History Museum of Lviv, since 1948). This article discusses four parchment folia from Kraków (The Princes Czartoryski Library, Poland) discovered in July 2020. Paleographical, orthographical, linguistic and textological features indicate that this section is the previously lost part of the Apostolus Christinopolitanus (excerpts from Act 13,5–20, 15,29–16,4, 1Tim 4,8–5,4 and 2Tim 1,10–2,4). The Kraków folia are the continuation of the Kyiv part and the beginning and final part of the Lviv part of the codex. The Kraków part was detached before 1888, when the manuscript was shown to the public at the Lviv Stauropegion Institute Exhibition and described and foliated for the catalogue by Antonij Petruševič. This article contains photocopies of all of the newly-discovered fragments.
Rozważania nad problemem nakładu Statutu Jana Łaskiego
Authors: Graś Wojciech
Published: March 2023

Artykuł porusza zagadnienie nakładu egzemplarzy pergaminowych oraz papierowych Statutu Jana Łaskiego. Problem ten rozpatrywany jest w dwóch aspektach. Po pierwsze, przybliżono i usystematyzowano funkcjonujące w literaturze przedmiotu poglądy na temat liczby wydrukowanych egzemplarzy. Krytyce poddany został najwcześniejszy, pochodzący z końca XVIII wieku, przekaz autorstwa Tadeusza Czackiego traktujący o nakładzie Statutu. Został on skonfrontowany z obecnym stanem wiedzy o oficynie Jana Hallera. W dalszej części ukazane zostało to, w jaki sposób pogląd o skromnym nakładzie Statutu był powielany w kolejnych publikacjach. Po drugie, przedstawiono rozważania na temat funkcji egzemplarzy pergaminowych oraz papierowych, ich przeznaczenia oraz potencjalnie różnego finansowania nakładu na poszczególnych tworzywach. Całość uzupełniają uwagi na temat prawdopodobnej liczby wydrukowanych egzemplarzy poczynione na podstawie dostępnych źródeł oraz zachowanych do dzisiaj egzemplarzy Statutu.
Zbiory funeralne w zasobach Pracowni Dokumentów Życia Społecznego Biblioteki Uniwersyteckiej w Poznaniu – nekrologi i obrazki komemoratywne
Authors: Urbańska Agnieszka
Published: March 2023

Tekst traktuje o zbiorach funeralnych znajdujących się w zasobach Pracowni Dokumentów Życia Społecznego Biblioteki Uniwersyteckiej w Poznaniu. Należą do nich m.in. nekrologii oraz obrazki komemoratywne. Oba rodzaje  tekstów można zróżnicować ze względu na funkcję i cechy zewnętrzne, łączy je natomiast konsytuacyjność w odniesieniu do śmierci konkretnej osoby. Zarówno  nekrologi, jak i karty pogrzebowe pozostają ważnym źródłem do badań.
Bioelectrical impedance phase angle is associated with physical performance before but not after simulated multi‐stressor military operations
Authors: Varanoske Alyssa N. , Harris Melissa N. , Hebert Callie , Johannsen Neil M. , Heymsfield Steven B. , Greenway Frank L. , Ferrando Arny A. , Rood Jennifer C. , Pasiakos Stefan M.
Published: March 2023

Physical performance decrements observed during multi‐stressor military operations may be attributed, in part, to cellular membrane dysfunction, which is quantifiable using phase angle (PhA) derived from bioelectrical impedance analysis (BIA). Positive relationships between PhA and performance have been previously reported in cross‐sectional studies and following longitudinal exercise training programs, but whether changes in PhA are indicative of acute decrements in performance during military operations is unknown. Data from the Optimizing Performance for Soldiers II study, a clinical trial examining the effects of exogenous testosterone administration on body composition and performance during military stress, was used to evaluate changes in PhA and their associations with physical performance. Recreationally active, healthy males (n = 34; 26.6 ± 4.3 years; 77.9 ± 12.4 kg) were randomized to receive testosterone undecanoate or placebo before a 20‐day simulated military operation, which was followed by a 23‐day recovery period. PhA of the whole‐body (Whole) and legs (Legs) and physical performance were measured before (PRE) and after (POST) the simulated military operation as well as in recovery (REC). Independent of treatment, PhAWhole and PhALegs decreased from PRE to POST (p < 0.001), and PhALegs, but not PhAWhole, remained lower at REC than PRE. PhAWhole at PRE and REC were associated with vertical jump height and Wingate peak power (p < 0.001–0.050), and PhAWhole at PRE was also associated with 3‐RM deadlift mass (p = 0.006). However, PhA at POST and changes in PhA from PRE to POST were not correlated with any performance measure (p > 0.05). Additionally, PhA was not associated with aerobic performance at any timepoint. In conclusion, reduced PhA from PRE to POST provides indirect evidence of cellular membrane disruption. Associations between PhA and strength and power were only evident at PRE and REC, suggesting PhA may be a useful indicator of strength and power, but not aerobic capacity, in non‐stressed conditions, and not a reliable indicator of physical performance during severe physiological stress.
How I Met Your Fans: A Comparative Textual Analysis ofHow I Met Your Motherand Its Reboots
Authors: Kocak Can
Published: March 2023

SinceHow I Met Your Mother(HIMYM) ended in 2014 with its ninth season, there have been multiple attempts to create a new series based on a similar premise – one parent telling their kid(s) how they met their other parent.How I Met Your Dad(HIMYD), which was planned to begin in 2014 right after HIMYM’s final, was not picked up by any network, whileHow I Met Your Father(HIMYF), which started airing in 2022, is continuing a successful [Upon its release, the show, whose premiere was watched in 420 K households, held the fifth place on the TV time charts and went on to stay on the list for four more weeks (The Entertainment Strategy Guy).] run, currently in its second season. This article compares the narrative and narration of the first episodes of these three series, including themes, recurring jokes, sound and visual effects, introductions of important characters and the “missing” parent, as well as the use of cameos. By doing this, it aims to delve into the reason behind why one of these reboot attempts was favoured over the other. The answer is provided as the difference between the amount of fan service in HIMYD and HIMYF, with the latter establishing more direct connections with HIMYM. In addition to becoming a rather common tendency by creatives, this article claims that fan service also seems to be used by networks and production companies as a way of ensuring audience engagement.
A study of somatic BRCA variants and their putative effect on protein properties in malignant mesothelioma
Authors: Krishnamurthy Kritika , Oh Kei Shing , Alghamdi Sarah , Sriganeshan Vathany , Poppiti Robert
Published: March 2023

Objectives

The aim of this study is to analyze the prevalence of somatic mutations in BRCA1 and BRCA2 in malignant mesothelioma and their putative impact on protein properties.

Methods

Eighteen cases of malignant mesothelioma were retrieved from the archives and for next generation sequencing analysis of BRCA1 and BRCA2 genes. Variants were analyzed using Ensembl VEP17, Polyphen 2.0 software, SIFT software, MutpredV2, and SWISS-MODEL homology-modeling pipeline server.

Results

BRCA2 variants were found in significantly higher percentage (22%) of cases (p=0.02). Five missense variants were identified. These were p.A2351P, p.T2250A, p.A895V, pG1771D, and p.R2034C. The SIFT scores of all except one were ≥ 0.03. The Polyphen scores of these four alterations were ≤0.899. In case of p.A2315, the SIFT score was 0.01, while the Polyphen 2 score was 0.921. MutPred2 scores were ≤0.180 for all. Loss of intrinsic disorder was predicted (Pr=0.32, p=0.07) for p.R2034C, while gain of intrinsic disorder was predicted for p.A2351P (Pr=0.36, p=0.01) and p.G1771D (Pr=0.34, p=0.02).

Conclusions

BRCA2 somatic variants were identified in 22% cases of malignant mesotheliomas in this study. The variants localize more frequently to the disordered regions of the protein and are predicted to affect the level of disorder.
Process configuration of combined ozonolysis and anaerobic digestion for wastewater treatment
Authors: Otieno Benton , Khune Mervyn , Kabuba John , Osifo Peter
Published: March 2023

Industrial activities and increased human population have made wastewater streams not entirely amenable to conventional treatment methods. Anaerobic digestion (AD) can treat such wastewaters with the advantage of bioresource recovery. However, the presence of solids and recalcitrant compounds in most wastewater streams may affect the AD process. Thus, combining AD with advanced oxidation processes (AOPs) such as ozonolysis is necessary. Ozonolysis can improve the biodegradability of wastewater substrates or eliminate biorecalcitrant pollutants that escape the AD process. This study combined ozonolysis with AD to treat waste activated sludge (WAS) and distillery wastewater (DWW). When applied as a pre-treatment, ozonolysis caused the rigid cell walls in WAS to rupture and solubilised the extracellular polymeric substances (EPS), leading to increased biodegradability. For the DWW, ozonolysis pre-treatment reduced the biorecalcitrant aromatic compounds to simple aliphatic compounds, thereby increasing biodegradability. In the ensuing anaerobic process, the WAS pre-treatment improved TSS and COD reductions and a 230% increase in cumulative biogas production. For the DWW, the ozonolysis pre-treatment did not significantly impact COD reduction or biogas production; however, ozonolysis as a post-treatment removed the color causing biorecalcitrant melanoidins from the anaerobically digested effluent and solubilised the sludge (TSS) washed out from the AD unit. Therefore, the AD-ozonolysis process configuration depends on the substrate being treated. Ozonolysis is best applied pre-AD for WAS treatment and post-AD for DWW.
Niederschwellig, flexibel, digital – Seelsorge auf Instagram
Authors: Lindena Insa Maren
Published: March 2023

Seelsorge wird schon seit den 1990er Jahren digital per Mail oder Chat angeboten. Seit einigen Jahren gibt es vermehrt auch Seelsorge auf Instagram. Um erste Einblicke zu erhalten, wurde ein Fragebogen entwickelt, der von drei auf Instagram seelsorglich aktiven Pfarrpersonen ausgefüllt und mittels qualitativer Inhaltsanalyse ausgewertet wurde. Die Ergebnisse vermitteln einen Eindruck, wie Seelsorge auf Instagram umgesetzt werden kann und welche Chancen und Herausforderungen dabei entstehen. Sie zeigen, dass die Selbstpräsentation als Pfarrperson sowie die angesprochenen Themen (z. B. Krankheit, Sterben, Beziehungsprobleme, Glaubensfragen) in Posts und Stories Anknüpfungspunkte zur Seelsorge auf Instagram bieten, die v. a. in den Privatnachrichten stattfindet. Die Chance der Instagram-Seelsorge liegt in ihrer Niederschwelligkeit sowie der zeitlichen und örtlichen Flexibilität, die besonders für weibliche, jüngere Personen im Alter von ca. 18 bis 45 Jahren attraktiv sind. Das unvorhersehbare Arbeitsaufkommen und der damit verbundene hohe Zeitaufwand werden wiederum als herausfordernd beschrieben. Auch die Wahrung des Seelsorgegeheimnisses wird aufgrund der Datenschutzprobleme als schwierig wahrgenommen. Doch ein Rückzug aus der Social-Media-Seelsorge scheint trotz der datenschutzrechtlichen Herausforderungen nicht angemessen. Vielmehr besteht die Notwendigkeit, neue Regelungen und technische Möglichkeiten zu entwickeln, um verantwortungsvolle und rechtlich abgesicherte Seelsorge auf Instagram weiterhin zu gewährleisten.
Possibilidades teórico-metodológicas entre raça (cor) e sindicalismo
Authors: Clímaco Alves Thompson
Published: March 2023

O presente trabalho é resultado de algumas considerações inicias de uma pesquisa em andamento. Dessa forma, não há o interesse em apresentar conclusões apressadas ou resultados parciais. Dito isso, o intuito do artigo é discutir, de forma propositiva, as relações entre raça e sindicalismo a partir de algumas pautas do Centro Operário de Barra Mansa durante a década de 1930. Para isso, são mobilizados debates inscritos na história social do trabalho (dos mais tradicionais aos mais recentes) sobre sindicalismo nos anos 1930, bem como às críticas à ausência da raça nos debates da área. Além disso, são apresentadas possibilidades teórico-metodológicas com o intuito de aproximar questões presentes nos sindicatos, que aparentemente não estão vinculados à raça diretamente, como: sindicalização dos trabalhadores rurais, instrução primária e assistência médica.
Aprimoramento da repressão à ociosidade no pós abolição (1888)
Authors: Stefanny Santos da Conceição Ingrid
Published: March 2023

O presente artigo tem como foco, a análise do combate à ociosidade no Brasil após a abolição da escravidão (1888). Nessa conjuntura, havia a expectativa que os ex-escravizados provocariam um caos social, ao passo que, o processo de repressão ao que se denominou de vadiagem foi fomentado pela emergência do Projeto nº33/1888 de autoria do Ministro da Justiça, Ferreira Vianna. O trabalho instrumentalizou-se da Análise de Discurso como método para problematizar a apresentação do Projeto nº33/1888, concomitante à luz da teoria da Criminologia Crítica. Observou-se que o Projeto nº33/1888 possuía um viés de controle social e racial, visando integrar por meio do trabalho compulsório os ex-escravizados. O artigo, dentro de seus limites, busca trazer uma contribuição sobre o pós abolição e a marginalização social, salientando a negação de cidadania a determinados extratos sociais na sociedade brasileira.
Faking It, Finishing, and Ambivalence
Authors: Frischherz Michaela , Rowe Desirée D.
Published: March 2023

This essay analyzes the transcription of critical focus group conversation among women to understand failure within their sexual lives. Against the backdrop of normative sexual scripts, women discuss faked orgasms and lackluster sex. Practicing a reparative reading method, we explore the relationship between failure, ambivalence, and sex in conversation. We conclude that the focus on women’s lived experiences highlights the reparative possibilities of ambivalent discussions surrounding failure; failure and ambivalence in sex are neither endgame nor roadblock. Instead, failure and ambivalence are constitutive of the gray areas of sexual communication, which contain within them moments of agency, pleasure, and power.
Fuck It
Authors: Smithers Laura
Published: March 2023

Profane methodologies is one way to describe research practices as creation rather than categorization and optimization. This essay takes on the utterance of fuck it, ubiquitous in late capitalism, as a spark that profanes methodologies. The essay explores the creative potential of fuck it in research methodologies in three ways. First, fuck it is situated within existing modes of inquiry. Second, fuck it is discussed as a performative that creates both an impasse and aesthetic. Third, fuck it is explored in three locations using both low theory exemplars and data from an ongoing post qualitative inquiry.
The Van Gogh Experience
Authors: Borchard Kurt
Published: March 2023

This experimental writing both embodies and interrogates how creative work that is re-mixed and re-presented also creates multivalent “experiences.” A menagerie of quotations performs both a narrative-of-thinking and open-ended discursive potential. The work asks: Can this manuscript both analyze and perform a subversion, problematizing notions of authenticity, authorship, ownership, production, distribution, reception, and meaning? Can immersion in fragmented, derivative writing produce an affective experience in line with a contemporary post-pandemic and technologically- and social-media-immersive “structure of feeling”? The excerpts include discussions of Vincent Van Gogh’s work recently presented as popular “immersive experiences”; discourse on the commodification, reproduction, and authenticity of art; views on artistic presentation in a pandemic- and technology-infused era; and quotations concerning (and drawn from work in) deconstruction, authorship, and avant-garde fiction, further extending interpretative potential. Where does it start, where does it take you, and where do you feel it?
The correlation of surface roughness and tool edge condition under sustainable cryogenic machining
Authors: NURUL HAYATI ABDUL HALIM  , CHE HARON CHE HASSAN , ABDUL GHANI JAHARAH , AZHAR MUAMMAR FAIQ , M.Z. Zulkifli
Published: March 2023

This paper investigates the correlation between surface roughness of Inconel 718 and tool edge condition of ball nose inserts when milled at high speed. The cutting parameters were varied as follows; cutting speed: 120–140 m/min, feed rate: 0.15–0.25 mm/tooth, and axial depth of cut: 0.3–0.7 mm. For a sustainable machining approach, the experimental works were carried out under a smooth supply of cryogenic coolant which is a mix of liquid CO2, gas CO2, and compressed air. The experimental results revealed that the range of surface roughness obtained is from 0.114 to 0.197 µm. Along the cutting process, the tool wear patterns such as the abrasion, chipping, and the intermittent build-up-edge near the depth of cut cause the rapid increase of tool wear as well as the roughness of the machined surface with a significant correlation between them. However, the roughness was slowly reduced and became stable with the increase of notch wear. The finding could be used as a prediction reference for monitoring surface roughness and tool wear progress under cryogenic conditions. It also provides foundations for further research on machinability under this sustainable approach.
Determinanty konkurencyjności produkcji przemysłowej krajów Grupy Wyszehradzkiej
Authors:   Uniwersytet Ekonomiczny w Krakowie, Ulbrych Marta , Lesiak Jakub ,   Uniwersytet Ekonomiczny w Krakowie
Published: March 2023

Purpose – The purpose of the article is to present the results of the study on determi-nants, measurement and analysis of changes in the competitiveness of manufacturing in the Visegrad Group countries against the selected EU countries, with particular emphasis on the environmental dimension. Research method – To achieve the goal of the paper, the method of analysing the source material and the available statistical data for the selected years of the period 2004–2019 was used.Then, the formal and statistical significance of the criteria and selection of indicators was performed, and deductive inference was carried out according to the results of taxonomic analysis using the Hellwig linear ordering method. Results – On the basis of the collected material and the conducted analysis, a ranking of the manufacturing competitiveness was established based on a synthetic measure.The Czech Republic turned out to be the leader within the Visegrad Group, while Poland achieved the worst results. Originality / value / implications / recommendations – The subject of the study, i.e. the factors determining the competitiveness of manufacturing in the changing macro economic environment, is important and up -to-date.The article is an attempt to organise the contemporary determinants of manufacturing competitiveness.The conducted research and formulated conclusions fill the existing gap as regards taking into account the challenges related to the climate and energy transformation, thus contributing to further considerations.
Ovisnost o internetu kod adolescenata
Authors: Mavar Mladen
Published: March 2023

Uporaba interneta, koji je neupitno koristan i praktičan, danas je nezaobilazni dio svakodnevnice. U značajnoj mjeri je i izvor problema, što se očituje kod onog dijela populacije kod kojega je evidentna nemogućnost kontroliranja vremena provedenog u aktivnostima na internetu. Rezultat toga je nastanak brojnih i različitih psihosocijalnih problema koji narušavaju funkcionalnost pojedinca i društva u cjelini te je na temelju toga opravdano govoriti o ovisnosti o internetu. Ovisnost o internetu smatra se vrstom bihevioralne ovisnosti, uključuje razvoj specifičnih mentalnih i ponašajnih oštećenja i problema karakterističnih za ovisničko ponašanje, ali bez uporabe psihoaktivnih sredstava kao uzroka same ovisnosti. Istraživanja prevalencije sustavno ukazuju na globalni porast ovisnosti o internetu s višim stopama u azijskim zemljama u odnosu na Europu i Ameriku. Kao jedan od problema procjene stopa prevalencije ističe se nedostatak jednoznačnih kriterija za definiranje ovisnosti o internetu kao i nedostatak kulturalno nepristranih, pouzdanih mjernih instrumenata. Ono što je posebno zabrinjavajuće je evidentan porast problema ovisnosti o internetu među adolescentima, zbog čega je važno daleko veći naglasak staviti na implementaciju novih znanja, redovitu provjeru postojećih i uvođenje novih preventivnih aktivnosti te podizanje svijesti o potencijalnim opasnostima prekomjernog korištenja interneta. Cilj ovoga istraživanja ponuditi je pregled podataka dobivenih iz istraživanja o prevalenciji, klasifikaciji, simptomima te prevenciji ovisnosti o internetu kod adolescenata.
Metafizička antropologija Tome Akvinskoga
Authors: Dadić Borislav , Poljak Maja
Published: March 2023

Antropološka misao Tome Akvinskoga, kao što sam naslov članka kaže, vezana je za metafiziku. Stoga razumijevanje njegove antropologije pretpostavlja poznavanje temelja tomističke metafizičke misli. U članku ćemo se susresti s pojmovima kao što su potencija, akt, forma, materija, bitak itd. te ćemo vidjeti kako Toma pomoću njih objašnjava posebnost ljudske duše u odnosu na druge forme i njezin odnos s tijelom. U prvom dijelu kratko se zaustavljamo na pregledu hijerarhije bića u Tominoj kozmologiji u kojoj čovjek zauzima posebno mjesto između dva svijeta: nematerijalnog i materijalnog. Upravo ta posebnost čovjekove pozicije u kozmološkom poretku Tomi nudi objašnjenja za neke specifičnosti ljudske duše zahvaljujući kojoj on čini posebnu vrstu bića. U drugom je dijelu članka riječ o pojedinim vlastitostima ljudske duše u odnosu na biljnu i životinjsku, kao što su njezina samostalnost i besmrtnost, dok je treći dio posvećen odnosu duše i tijela. Naposljetku u članku nalazimo kratki pregled Tomine filozofije spoznaje u kojoj pitanje razuma dolazi u prvi plan. Iz prethodno rečenoga jasan je cilj članka – pregled temeljnih tema Tomine antropološke misli.
Métodos de colaboración en las comedias de varios ingenios: el caso de El mejor amigo, el muerto
Authors: Campión Larumbe Miguel
Published: March 2023

Hay varias teorías sobre los métodos de colaboración en las comedias de varios ingenios del Siglo de Oro. Se especula con la composición sucesiva o simultánea, el uso de planes argumentales previos o la fase de corrección de borradores. También hay controversia sobre las razones por las que colaboraban; encargos de última hora, sociabilidad literaria, experimentación o atractivo comercial. Para resolver estas cuestiones, sería necesario analizar cada obra antes de extraer conclusiones generales. En este artículo se estudia el caso de El mejor amigo, el muerto de Belmonte, Rojas Zorrilla y Calderón, para tratar de dilucidar qué métodos de colaboración utilizaron sus autores.
Los puentes entre Manuel Vázquez Montalbán y el EZLN: cronología e intercambio textuales (II)
Authors: García García Sergio
Published: March 2023

Este estudio, dividido en dos partes, tiene como propósito principal la realización y el análisis del corpus de los textos periodísticos, ensayísticos y de ficción que Manuel Vázquez Montalbán dedicó a la causa del ezln entre 1994 y 2003; asimismo, presta atención a la relación de este autor con el subcomandante Marcos, con el fin de determinar un imaginario global montalbaniano en torno al neozapatismo. Además, la relación del escritor con Chiapas se complementa con el estudio de varias obras de Marcos donde Vázquez Montalbán aparece como referente intelectual y como materia literaria, entre las que destaca la novela Muertos incómodos (falta lo que falta), escrita junto con Paco Ignacio Taibo II.
Identification of antimicrobial compounds in different hydrophilic larch bark extracts
Authors: Wagner Kerstin , Roth Caroline , Willför Stefan , Musso Maurizio , Petutschnigg Alexander , Oostingh Gertie Janneke , Schnabel Thomas
Published: March 2023

Larch bark is an undervalued material, but it has unique and valuable characteristics and compounds. The objective of this study was to extract and characterize molecular compounds of bark materials from different larch trees and to test these for their antimicrobial properties. The extractions were performed using methanol or water. The obtained extracts were analysed by gas chromatography coupled to mass spectrometry (GC-MS). Antimicrobial properties also were determined using different microbial strains, for example, Staphylococcus aureus. The GC-MS analysis showed that long chain alcohols, fatty acids, and polyphenols were present in the extracts. According to the results of the agar diffusion tests, only the methanol extract of larch bark had an inhibitory effect on the growth of Staphylococcus aureus. Two compounds of flavonoids and stilbenoids were shown to affect the microbial activity of the larch bark. Therefore, larch bark can be used for the extraction of compounds with specific anti-microbial properties.
Improving the adhesion of high-density softwoods with isocyanate based adhesives through surface incision
Authors: Vella Rodney , Heitzmann Michael T. , Redman Adam
Published: March 2023

Glue laminated timber is currently manufactured using classical adhesives such as resorcinol formaldehyde and phenol resorcinol formaldehyde. These are proven structural adhesives; however their long cure times and rising costs are creating opportunities for newer technology adhesives. One such class are the structural polyurethanes with decreased spread rates and faster curing times. Their limitation lies in their inability to adhere timbers of densities exceeding 800 kg/m3. When used on species including the southern pines (Pinus spp.) with a high frequency of latewood, they delaminate after accelerated weathering tests due to stresses imposed on the glue line during the drying process. Surface incision has been trialed in this study to increase the penetration of polyurethane adhesives and reduce glue line stresses. The study shows that incisions to a depth of 2 mm decreases delamination when compared to matched samples with no incisions. The significant increase in glue line surface area may result in stress reduction as the more compliant adhesive may distribute the stresses better across the glue line. Furthermore, microscopic analysis suggests that the incisions are reducing glue line stress through crack propagation into the timber pointing to the possibility of increased timber compliance at the glue line.
Effects of thermal treatment on the mechanical properties of larch (Larix gmelinii) and red oak (Quercus rubra) wood cell walls via nanoindentation
Authors: Wu Yan , Zhang Haiqiao , Zhang Yang , Wang Siqun , Wang Xinzhou , Xu Deliang , Liu Xiang
Published: March 2023

Thermally treated wood is widely used for construction, furniture, and flooring because it has better dimensional stability in outdoor conditions. There is a close relationship between the mechanical properties of thermally treated wood cell walls and the performance of its products. The hardness (H) and reduced elastic modulus (Er) of larch (Larix gmelinii) and red oak (Quercus rubra) wood cell walls were investigated via nanoindentation. The results showed that the larch and red oak wood specimens had different nanomechanical properties. The Er in the larch wood initially increased with a maximum value of 22.4 GPa at 225 °C, then rapidly decreased after 300 °C with a minimum value of 5.7 GPa at 350 °C. The Er in the red oak wood appeared to have a mild decline. The H in both wood species visibly increased with the thermal treatments due to the reduction of organic wood polymers and the increase of inorganic carbon materials.
Fiberboard made from scrap denim: Characterization of its properties by effective bulk modulus elastography
Authors: Shi Sheldon Q. , Cui Zhiying , Jin Yuqi , Smith Lee , Wu H. Felix , Neogi Arup
Published: March 2023

Fiberboards from scrap denim were fabricated using two different resins, melamine urea formaldehyde (MUF) and polymeric methylene diphenyl diisocyanate (pMDI). Resin content and MUF-pMDI weight ratio were studied. Physical and mechanical tests determined the modulus of elasticity (MOE), modulus of rupture (MOR), internal bond (IB), thickness swell (TS), and water absorption (WA). The resin content had significant impact on all properties. The MOE and IB were affected by the MUF-pMDI ratio. With 17 wt% more pMDI resin portion in the core layer of the denim boards, the IB for the denim fiberboard with a resin content of 15% was enhanced by 306%, while by 205% for the resin content of 25%. The increase in pMDI portion in the core layer of the boards improved both TS and WA of the scrap denim fiberboard. Effective bulk modulus elastography (EBME) was used to measure the acoustic reflection for the estimation of the strength properties of the denim fiberboard. The modulus results from EBME were correlated to the MOR, MOE, and IB of the denim fiberboard. A high correlation was found between the modulus from EBME and IB (R2 > 0.98). EBME can be a great technique to evaluate the bulk modulus distribution of the composites.