bluuebunny/crossref_metadata_2025 huggingface dataset:
What a Difference 35 Years Can Make
Authors: Worthington, Jr. Everett L.
Published: May 2016

I review changes in social trends, psychological science, psychotherapy practice, and theology—
which have been so profound they have often seemed like revolutions—since the landmark publication
by Allen E. Bergin, “Psychotherapy and Religious Values,” in 1980. I attempt to predict some current and
future trends that will shape the practice and research in the treatment of religious people for psychological
disorders, including theological changes toward more open theology, less doctrinally centered religions,
more attention to individual spirituality, and more relational psychology and theology. In the field of
psychotherapy research, efficacy studies are no longer the gold standard of research, replaced by large trials
demonstrating effectiveness and dissemination. The expensive research required will likely cut the amount
of research done on religiously and spiritually accommodated treatments; thus winnowing of treatments
is likely in the future. Practitioners will need to become competent to counsel people using many religious
and spiritual accommodations. I acknowledge that predicting the future accurately is at best tentative, and
I urge that this be read with circumspection.
Rediscovery of Early Twentieth-Century Ecotheology
Authors: Pihkala Panu
Published: May 2016

In this article, I examine the early history of Christian environmentalism (“ecotheology”)
in the twentieth century. I delineate four strands of early ecotheology: agrarian ecotheology; social
Christianity; British contributions; and “post-liberal” foundations for later ecotheological movements. I
show that ecotheology was a slowly-rising movement, which had notable proponents. I argue that these
early ecotheologians are significant for several reasons. First, these writings support the view that there
are momentous roots of environmentalism in the late 19th and early 20th Century. Second, these texts
reveal important information about the relation of Christian and other environmentalism. Third, early
ecotheologians contributed to discussion about themes which would later form distinctive environmental
disciplines, such as environmental aesthetics, education, ethics, history and philosophy. Their thoughts
offer interesting reflections pointing to these fields. Fourth, the contributions by the early ecotheologians
are not only historically interesting, but they have relevance for the current discussion. These theologians
were in a special position to notice the major changes brought by technological development in the twentieth
century and they provided important critical reflections about these issues. Because they developed their
thought independently, they display creative thinking, although often in an unfinished manner.
Interspiritual Theology as a Radical Potential
for New Vistas in Theological Thought
Authors: McEntee Rory
Published: May 2016

Is a transreligious theology possible? A theology that is not beholden to any particular religious
tradition? If so, what would it be? What would it look like? How would it be done? Perhaps more importantly,
why would it be done? That is, whom would it be for? Is it a part of a larger (and perhaps privileged) pursuit
of human philosophical wisdom and progress? Or are there real world communities in need of such a thing?
Could it be helpful to religious traditions themselves? These are some of the questions pursued here. In
response, I offer the possibility of an “interspiritual theology,” a theology that opens widely—in the spirit
of exploration and hypothesis—to such questions, while aiming not to lose the heart of the theological
endeavor, articulated by Evagrius of Pontus as, “The one who truly prays is a theologian; the one who
is a theologian, prays truly.” As one possible strand of transreligious theological thought, interspiritual
theology finds resonance with contemporary academic scholars Robert Neville, Wesley Wildman, John
Thatamanil, Beverly Lanzetta and the late Raimon Panikkar, as well as real-world movements on the
ground springing up outside of academia. Interspiritual theology is explained as being inter-religious,
interdisciplinary, pragmatic, contemplative, and prophetic. An academic endeavor that is in partnership
with (but not beholden to) religious traditions, in service to spiritual communities outside of academia, in
dialogue with secular sciences, partaking of transformative wisdom, and committed to the prophetic task of
service to humanity and the transformation of all of its social, cultural, political, and economic structures
to reflect the deep human values of dignity, equality, compassion, love and wisdom—while also pursuing
the transreligious project of understanding “as fully as possible the nature of ultimate reality.”
At the Threshold of Representation: Cremation and Cremated Remains in Classical Latin Literature
Authors: Habinek Thomas
Published: May 2016

This paper considers a set of passages from classical Latin literature of the first century BC and first century AD that indicate awareness of the particular transformations undergone by a human body during the process of open-air cremation. Evidence for the extent of cremation throughout the Roman West is reviewed, as are indications that mourners frequently remained near the pyre throughout the lengthy transformation of the corpse into bone-remnants and ash. In addition, archaeological, ethnographic, and forensic evidence documenting the step-by-step changes undergone by the burning body is introduced. Against this backdrop, numerous passages from authors such as Horace, Vergil, Propertius, Tibullus, Ovid, Seneca, Lucan, Statius, and Suetonius take on new significance. Although authors occasionally cite crematory details as such, they more frequently make use of such details in non-crematory contexts in order to achieve a variety of literary and aesthetic goals, including economy of description, reflection on the circulation of substance, and clarification of the process of ekpyrosis, or cosmic conflagration. For these writers considered as a group cremation serves as an indicator of both the abject nature of the human condition and of its potential sublimity. The calculated displacement of key aspects of the crematory process onto non-crematory events and practices mirrors and extends the liminality associated with crematory rites.
The Use and Abuse of Training “Science” in Philostratus' Gymnasticus
Authors: Stocking Charles H.
Published: May 2016

This article addresses how the sophistic-style analysis in Philostratus' Gymnasticus gives expression to the physical and social complexities involved in ancient athletic training. As a case in point, the article provides a close reading of Philostratus' description and criticism of the Tetrad, a four-day sequence of training, which resulted in the death of an Olympic athlete. To make physiological sense of the Tetrad, this method of training is compared to the role of periodization in ancient medicine and modern kinesiology. At the same time, Philostratus' own critique of the Tetrad is compared to Foucauldian models of discipline and bodily attention. Ultimately, it is argued that the Tetrad fails because it does not incorporate καιρός, a theme common to athletics, medicine, and rhetoric. Overall, therefore, Philostratus' critique of the Tetrad helps us to appreciate the underrepresented role that γυμναστική occupied in the larger debates on bodily knowledge in antiquity.
Heideggerian Mathematics
Authors: Hunter Ian
Published: May 2016

This paper provides a historical redescription and reinterpretation of Alain Badiou’s major work, Being and Event. The work is approached historically, as a text that uses Heideggerian metaphysics to perform an allegorical exegesis of mathematical set theory and does so as a means of fashioning a supremacist spiritual pedagogy for a philosophical elite in the context of a national intellectual subculture.
From Virtue to Surplus
Authors: Soll Jacob
Published: May 2016

This article explains how, during the time of the French Revolution, the financial language of accounting became part of modern political discourse with surpluses representing virtue, and deficits, failure.
The Historical Society of Southern California’s Hidden Treasures, Including an Angeleno’s Civil War Diary and Letter
Authors: Spitzzeri Paul R.
Published: May 2016

An account of the discovery of artifacts in the collection of the Historical Society of Southern California. Highlighted is the Civil War diary and a letter written by Charles Myers Jenkins, the only enlistee from Los Angeles to see combat for the Union during the Civil War. Included is a transcription of the November 1864 letter Jenkins wrote to his mother after his release from a Confederate prisoner-of-war camp.
Seamus Heaney at Berkeley, 1970–71
Authors: O’Shea Edward
Published: May 2016

Irish poet Seamus Heaney spent the 1970–71 academic year as a visiting professor at the University of California, Berkeley. He had come from Northern Ireland in the time of the Troubles; he arrived at a campus stirred by anti-war protest. This article explores the impacts of Heaney’s time in Berkeley on his poetry.
Transnational and Local-Focus Ethnic Networks
Authors: Hung Yu-Ju
Published: May 2016

While nineteenth-century Chinese immigrants took comfort in social organizations based on networks carried over from China, this case history of recent Chinese immigrant communities in the San Gabriel Valley finds two kinds of social organizations operating complementarily. Transnational organizations, based on networks established in regions of origin, sustain community bonds among immigrants and their offspring. Local-focus organizations are a new type, formed among Chinese American suburbanites to empower them in local issues.
Effect of Patient-Centered Medical Home on Preventive Services for Adolescents and Young Adults
Authors: Garcia-Huidobro Diego , Shippee Nathan , Joseph-DiCaprio Julia , O’Brien Jennifer M. , Svetaz Maria Veronica
Published: May 2016

OBJECTIVE:

To determine the association between enrollment in patient-centered medical homes (PCMHs) and the receipt of preventive services among adolescents and young adults.

METHODS:

Retrospective cohort study including patients of Hennepin County aged 10 to 24 who had face-to-face or telephone encounters with health care providers between 2010 and 2014 at clinics with PCMHs at the Hennepin County Medical Center, Minnesota. Exposure was enrollment in PCMHs. Outcomes were receipt of (1) preventive visits; (2) prescriptions for influenza, meningococcal, and human papillomavirus vaccinations; (3) screening for sexually transmitted infections; (4) prescription of any contraceptive and long-acting reversible contraceptives; and (5) cervical cancer screening. Generalized mixed effect models in a propensity-score-matched sample were used for data analysis.

RESULTS:

Overall, 21 704 patients were included. Most patients were female, US-born, Hispanic/Latino, with an average age of 20.8 years. Patients enrolled in PCMH (n = 729) were more likely to be Latino, students, and have health insurance (P < .001). Adjusted odds ratios (99% confidence intervals) comparing the receipt of preventive services of patients enrolled in PCMHs to youth who did not receive these services were as follows: (1) preventive visits 1.10 (0.93–1.29); (2) influenza 0.89 (0.74–1.07), meningococcal 1.53 (1.30–1.80), and human papillomavirus vaccinations 1.53 (1.28–1.84); (3) screening for sexually transmitted infections 1.69 (1.28–2.24); (4) prescription of any type of contraception 2.18 (1.56–3.03) and long-acting reversible contraceptives 2.66 (1.89–3.74); and (5) cervical cancer screening 1.14 (0.87–1.48).

CONCLUSIONS:

Overall, patients enrolled in PCMHs had higher odds of receiving multiple preventive services.
Y-глутамілтрансфераза в моделі канцерогенезу у щурів
Authors: Babij S. O. , Djomshina O. O. , Shtemenko N. I.
Published: May 2016

For the first time activity of membrane bound and soluble forms of γ-glutamyl transferase in the rat erythrocytes under the model tumour in vivo and under correction of the pathological state by complexcompounds of rhenium (III) with organic ligands and cisplatin (rhenium-platinum system) was studied. The increased activity of the membrane bound enzyme and decrease of its cytosolic activity in the red blood cells during development of Guerin’s carcinoma T8 was found. Also the positive impact of the rheniumplatinum system on the enzymatic activity in the erythrocytes was shown, namely: the reduction of membrane bound and increase of cytosolic activity. As a result, the ratio between activity of the membrane bound enzyme and cytosolic one verged towards the correct level. The conclusion was made that the use of membrane bound and soluble γ-glutamyl transferase in the erythrocytes as a diagnostic enzyme of carcinogenesis is reasonable.
Вплив умов культивування на біосинтез протеолітичних ферментних комплексів Yarrowia lipolytica
Authors: Goncharov A. M. , Gavriljuk V. G. , Matseljukh E. V. , Vinnikov A. I.
Published: May 2016

It was established, that production of proteolytic enzymes from yeasts is effected by sources of Carbon, Nitrogen and energy. The impact of different organic substances to proteo-, fibrino-, gelatine- and haemoglobinolytic enzyme activity from Yarrowia lipoytica 2061 is established. Positive effect of addition galactose and gelatin with glycine in cultural liquid is revealed. Optimal temperature, pH and other physical parameters for getting proteolityc enzyme complexes is defined.
Особливості накопичення важких металів органами та тканинами мікромамалій у різних за ступенем забруднення біогеоценозах
Authors: Zemliany О. А.
Published: May 2016

Microelements accumulation features are considered in micromammals’ organism taken from different degrees transformation biogeocoenosis of Dnipropetrovs’k region. Coefficients of accumulation are defined in different organs and tissues. Accumulation of heavy metals in the micromammals’ organism in different ecosystems, with a different technogenic contamination is heterogeneous. Organs which defined asconcentrators are spleen, heart and gonads. They have primary accumulation of heavy metals. Organs–deconcentrators are those which have active extraction of microelements (liver, kidneysand and intestine). Tendency to the decline of microelements accumulation intensity in animals from strongly transformed biogeocoenosis are stated. Formation of the special barriers of accumulation and excretion from organism by organs–deconcentrators testifies to making an adaptive mechanism at the level of physiology-biochemical processes and, first of all, the metabolism intensification.
Ординація та сітьовий аналіз угруповань павуків
Authors: Kunakh O. M.
Published: May 2016

The network approach is proposed to study the animal community with herpetobiont spiders of Dnipropetrovsk region as an example. The network representation is an alternative of an ordination paradigm in community structure description. The advantages of the network approaches in animal community analysis are shown. The possible directions of the herpetobiont spiders community formation of the steepe zone ofUkraine have been found. The effect of the forests on the steepe animals community is shown.
Катіонний склад слини у людей із порушеннями діяльності шлунково-кишкового тракту
Authors: Markina M. V. , Vyatkin О. V. , Lyashenko V. P. , Rudenko А. І.
Published: May 2016

Connection between the pathologies of alimentary canal and the changes of concentrations of microelements in human saliva is under consideration. The decrease of the cations content in saliva under forming and developing the pathological process in gastrointestinal tract is shown.
Екологічні особливості рідкісних родів актиноміцетів у ґрунтах Азербайджану
Authors: Abushova A. R. , Gasanova S. A. , Kasimzade M. A.
Published: May 2016

The results of the research of rare species of actinomycetes in some soils of Azerbaijan were studied. On the selective media the representatives of Streptomyces, Streptosporangium, Micromonospora, Actinomadura, Microbispora, Saccharopolyspora and Saccharomonospora were revealed. Species of Streptomyces and Micromonospora dominate in mountain-wood ecosystems (60 %.). It was established that among streptomyces species of Cinereus section of Violaceus series; Helvolo-Flavus sections of Helvolus series, Roseus sections of Fuscus series; Azureus sections of Coerulescens series. It was established that amount of termotolerant actinomycetes in the investigated desert soils of Azerbaijan depends on the incubation temperature. The species of Streptomyces, Micromonospora, Saccharopolyspora and Actinomadura genera were isolated from desert soils of Azerbaijan.
Залежність етологічних реакцій щурів із підлеглою поведінкою від типу партнера у тесті «перегородка»
Authors: Veselovskaya E. V.
Published: May 2016

The dynamics of the reactions of rats with submissive type of behaviour to known or unknown part-ners has been investigated under modelling of sensory contact in a «partition» test under the conditions of agonistic collisions. Testing the rats with submissive type of behaviour testifies to the fact that after the series of agonistic collisions the rats demonstrate increasing fear of a known partner-aggressor, but they keep the interest in an unknown partner in a «partition» test.
Порівняльний аналіз флористично-фауністичних комплексів у біогеоценозах Кримського Присивашшя
Authors: Gromenko V. M. , Ivashov A. V.
Published: May 2016

Prisivachie is the complicated ecological system which is considered as a landscape rank. At the same time the structure of the landscape includes a number of ecosystems of lower level – biogeocenoses. The specific structure of floristic and faunistic complexes of each biogeocenosis is established and studied. The comparative analysis of the complexes with the use of Jacquard's similarity coefficient has been carried out; the degree of their similarity has been revealed.
Вихровий вплив імпульсного магнітного поля на осмотичну резистентність еритроцитів щурів
Authors: Zadorozhna G. O. , Lyashenko V. P , Chaus T. G. , Lis A. , Tkachenko J. O.
Published: May 2016

The research of the dynamics of the osmotic resistance of erythrocytes of rats in the conditions of the influence of the vortical impulsive magnetic field has been provided. It has been discovered that the protracted magnetic field during 21 weeks modulates (changes) the studied index. The peculiarities of the action of right- and left-directed vortical influences of the magnetic field at their protracted use are examined. Under the prolonged action the effects of the vortical magnetic field of different orientation were different and became apparent at the beginning of the research. The action of the right-directed magnetic field caused the revival of the morphofunctional state of erythrocytes, while the left-directed one worsened it.
Культура ізольованих зернівок як біотехнологічна система дорощування зиготичних зародків кукурудзи in vitro
Authors: Lyapustina Е. V.
Published: May 2016

The investigation established the possibility of production of maize embryo in culture of isolated caryopsis on artificial nutrient medium in vitro conditions from a zygote / proembryo and globular stage up to the full maturity. It was determined that the cultivation of caryopsis on artificial nutrient medium provides the accumulation of starch in endosperm. The internal state of cultured caryopsis can be considered as a marker of embryo upgrowing and starch accumulation in endosperm, irrespective of the genotype. The genotype, the age of cultured caryopsis and concentration of sucrose influence on the development of endosperm, accumulation of starch in endosperm and embryo upgrowing from the zygote / proembryo and globular stage.
Вплив термічної стимуляції на біопотенціали листя кукурудзи
Authors: Motsnyj M. P. , Botsva N. P. , Vlasova S. V. , Elina О. V. , Matvij I. P.
Published: May 2016

Dynamics of maize leaves' biopotentials evoked by cold- and heat stimuli with two frequencies 0.05 and 0.1 Hz is analyzed. Potential amplitude dependence of heating rate and time interval between first and following stimuli during both heating and cooling was discovered. It is ascertained that following potentials' amplitude increases in time during heat stimulation and decreases in time during cold stimulation. Qualitative difference in the reaching of potential stabilization is established for both stimulation frequencies; and probable reasons of the difference are analyzed. Potential stabilization levels are fixed for each series of experiment.
Вплив нанопрепаратів кластерних сполук ренію на активність ферментів печінки в моделі пухлинного росту
Authors: Suponko J. V. , Shtemenko N. I.
Published: May 2016

Enzymes’ level in rat’s hepatocytes under Guerin's carcinoma T8 development as well as after injection of rhenium compounds and cis-platin has been studied. It has been determined that the decrease of enzymatic activity to the level of the animals of control group was observed at the simultaneous injection of cis-platin and cluster rhenium compounds in nanoliposomal and water-soluble forms. That confirms possible hepatoprotective properties of the rhenium compounds. It has been shown that hepatoprotective properties of rhenium cluster compounds mostly don’t depend on the form of their injection and are detected regardless of anticancer properties. Rhenium-platinum system with β-alanine ligand in aqueous solution, has been found. Its injection is accompanied by the hepatoprotective effect.
Рівень обмінних процесів організму поросят за умов уведення комплексних органічних сполук есенційних мікроелементів
Authors: Shapovalov S. O.
Published: May 2016

Use of preparations developed on basis of the microelements compounds is an efficient alternative to existed traditional approach to the prevention of metabolic disorders in animals. Obtained results enlarge understanding the mechanisms of antioxidant system activity and could be the basis for elaboration of scientific schemes of metabolism regulation with the help of different bioactive food supplements. Microelements complex “Biotam” stimulates proteins biosynthesis and increasing its level in the animals blood. It is proved that introduction of additional amount of microelements actuates the processes of proteolysis due to activation of pancreatic membrane enzymes.
Ідентифікація нелінійностей нейрональних систем спинного мозку методом псевдовипадкових стимулів
Authors: Shugurov O. O.
Published: May 2016

We have investigated nonlinear properties of integrative system of a spinal cord (SC) of cats by the method of pseudo-casual stimulation of nerves as well as the evoked potentials (EP) of SC. Nonlinearity of target reaction was estimated by calculation of nuclei of a Viner series. We have found the first three nuclei, which enabled us to describe adequately N1-components and Р-phase of EPSC. We have shown that for the descriptions of N2- and N3-components of EP one needs a calculation of nuclei of a high order.
Вплив комплексів заліза на формування фотосинтетичного апарату та вихід генетичних змін у гамма-опроміненого насіння пшениці
Authors: Shamilov E. N. , Abdullayev A. S. , Rzayeva I. A. , Azizov I. V.
Published: May 2016

Influence of various doses of γ-irradiation on biosynthesis of chlorophyll and carotinoids, and also on a progress of mitotic divisions of meristematic cells of root hairs at sprouting wheat seeds at the presence of pyrocatechol, iron pyrocatecholat, thiocarbamide, iron thiocarbamide, rutine, iron rutinate, juglon and iron juglonate was studied. There was revealed that iron pyrocatecholate, iron rutinate, juglon and iron juglonate possess appreciable radioprotective properties which stimulate adaptive biosynthesis of chlorophyll and carotinoids, and also considerably reduce a number of chromosomal aberrations under irradiation.
Екологічна структура угрупувань панцирних кліщів (Acariformes, Oribatei) ділянок рекультивації м. Жовті Води Дніпропетровської області
Authors: Shtirts А. D. , Kul’bachko Y. L. , Nikitenko А. V. , Didur О. A.
Published: May 2016

Taxonomical composition and ecological structure of Oribatei associates in recultivated territories  located near Zhovti Vody town are investigated. The artificial arboreal planting causes increase of oribatida number in comparison with recultivated areas without arbors. Planting of trees and presence of the leaf litter promote to redistribution of oribatida life-form and change of structure in their complexes. The positive influence of artificial forest ecosystems in technogenic landscapes of different stages of technical remediation on forming of Oribatei ecological structure is shown.
Вплив кластерних сполук ренію з органічними лігандами на активність глюкозооксидази
Authors: Voronkova Y. S. , Shtemenko N. I.
Published: May 2016

Influence of cluster rhenium compounds with different ligands on the activity of glucoseoxidase was studied. Ability of the rhenium compounds to influence on the enzyme’s activity was ascertained. Itis depended on the compound structure and the time of incubation: activity of the glucoseoxidase changed by 4–24 %. The cluster compound with GABA ligand reduced the enzymatic activity, but compounds with hydrophobic ligands increased the activity of glucoseoxidase. Different mechanisms of the cluster rhenium compound–enzyme interactions are suspected.
Кадмій у ґрунтах м. Дніпродзержинськ
Authors: Goon’ko S. A.
Published: May 2016

Data on cadmium distribution in the soils of industrial, residential and recreational areas of Dniprodzerzhinsk city are presented. According to the classification of urban soils the following types of soils were identified in the city: urban soil proper, plantosoil, anthropogenic-surface-transformed natural soil and lawn soil. We have made the estimation of cadmium content. The problem of soils contamination in the city with high anthropogenic load is discussed. The total cadmium content in the industrial, residential and recreational soils of Dniprodzerzhinsk varies within 0.6–10.5 mg/kg, but movable forms make 0.1–3.4 mg/kg of soil. Cadmium in the urban soil proper of the right-bank city surpasses the maximum permissible concentration (MPC) twice. At the same time the soils in the left-bank area and in the eastern and western areas of the right-bank were under MPC.
Влияние лецитина и казеина на спектр антимикробной активности бактериоцинов молочнокислых бактерий, изолированных из азербайджанских сыров
Authors: Gulahmedov S. G. , Huseynova N. F. , Abdullaeva N. A. , Kuliev A. A.
Published: May 2016

The influence of lecithin and casein on the antimicrobial activities of bacteriocins isolated from Lactobacillus paracasei spp. paracasei BN ATS 8w, Enterococcus faecium А5 andLactobacillus rhamnosus FAZ 16mstrains was studied. Lactobacillus bulgaricus 340, Listeria innocua СIP 80.11, Escherichia coli ATCC 23355, Enterococcus faecalis ATCC 1.144 were used as target organisms. Used concentrations of lecithin and casein – 0.1 % and 1–5 g/L respectively – were antagonistic to the bacteriocins. These substances are constituents of most fermented products.
Особливості реагування антиоксидантної системи нирок мишей на дію низькочастотної вібрації
Authors: Dotsenko O. I.
Published: May 2016

Influence of 14-day vibrations of 8, 16, 24 and 32 Hz frequencies with 0.8 ±0.12 mmamplitude on the activities of SOD–catalase and the glutathione system and on the content of reduced glutathione in mice kidneys homogenates is studied. The tissues hypoxia and decrease of the reduced glutathione in kidneys are shown. Carried out analysis of changes in the oxidizing processes and antioxidant protection enzymes testifies to decrease in capability of an organism to response adequately to such stressful factor as low-frequency vibration.
Вплив психотропних лікарських засобів на спонтанну поведінкову актиність білих щурів
Authors: Drozdov A. L. , Demchenko E. M. , Ejjyad A. , Nerush O. P.
Published: May 2016

Data obtained showed that using of neuroleptics in conditions of experimental psychosis was accompanied by the decreasing of mobility, investigative behavior and emotionality in experimental animals more than in intact ones. Asopposed to that, the action of atypical antipsychotic drug – sulpiride was characterized by the anxiety decreasing but the mobility increasing. The nootropic agents resulted in increasing of motor and emotional activity. The established pharmacological effects of neuroleptics, antidepressants and nootropic agents may use in clinical practice for treatment optimization of the patients with mental disability including schizophrenia.
Роль комісій підприємств з атестації робочих місць у професійній реабілітації осіб з обмеженими можливостями
Authors: Yеrochkina T. V. , Borisenko S. S. , Danilenko G. V. , Pologaj N. G.
Published: May 2016

The adequacy of physically challenged persons’ employment in companies depending on their health status and working environment was assessed. The sickness rate of workers on certified workplaces with safety labor conditions is three times less than on not certified ones, and the average disability days – 2.6 times less. The concept of improving the certification of workplaces of the disabled persons for the purpose of advance of their vocational rehabilitation is developed.
Вплив реній-платинової системи у вигляді наноліпосом на проліферативну активність ракових клітин
Authors: Kononova G. S. , Antonuk S. V. , Shtemenko N. I.
Published: May 2016

Decrease of proliferative activity of the cells of Guerin’s carcinoma T8 in the different conditions of administration of the Rhenium-Platinum anti-tumour system as nanolyposomes is shown. The Rhenium-Platinum anti-tumour system influenced on the morphological indices of tumour tissue. The cluster rhenium compounds reduced the indices of pathological mitoses 3.0–3.6 times in comparison with a control group. The amount of PCNA-positive cells under the Rhenium-Platinum system treatment went down by 82.5–84.5 %. The anti-tumour system led to the predominance of apoptotic cell death over the necrotic one. The most effective agent was the compound with cis-adamantan organic ligand cis-Re2(C10H15COO)2Cl4·2DMSO introducted on the 9th day.
Ефект попередників і модуляторів біосинтезу убіхінону на вміст і функціонування убіхінону та оксидативний статус у серці при введенні адреналіну
Authors: Kuchmenko O. B. , Petukhov D. M. , Yevstratova I. N. , Mkhitaryan L. S. , Donchenko G. V.
Published: May 2016

Preventive and/or subsequent application of precursors and modulators complexes of ubiquinone biosynthesis under the adrenaline treatment reduces free-radical lipid and protein peroxidation intensity, but increases superoxide dismutase activity and improves activities of the mitochondrial electron-transport chain complexes. EPM and EPMD complexes can be effective anti-hypoxic remedies that promote normalization of the energy metabolism in ischemic heart.
Зміни сумарної фонової електричної активності гіпокампа та поведінкових реакцій щурів при тривалому стресі
Authors: Melnikova O. Z. , Lyashenko V. P. , Chaus T. G. , Burceva D. A. , Kalyuzhnaya L. V.
Published: May 2016

The dynamics of power and waves spectral composition of total background electrical activity in hippocampus and changes of motor and investigative activity of rats during long-lasting stress were investigated. The dependence of analysed indices on duration of the stress influence was found. The correlation between hippocampus bioelectrical activity and behavioural reactions of rats were established.
Розповсюдженість карбапенемрезистентних штамів Pseudomonas aeruginosa – продуцентів метало-β-лактамаз
Authors: Nesteruk K. M. , Sokolova I. E. , Bratus O. V.
Published: May 2016

The existence of Gram-negative bacilli producing metallo-β-lactamase has been increasingly reported in many countries. The polyresistant strains of Pseudomonas aeruginosa isolated from patients’ urine were studied. The sensitiveness of strains to imipenem was assessed. The production of carbapenem-hydrolysing enzymes in resistant and moderately resistant strains was investigated. A high level of prevalence of the metallo-β-lactamase according to phenotypical test was showed. The necessity of monitoring of the distribution of carbapenem-hydrolysing enzymes producers is grounded.
Біологічні властивості бактерій роду Staphylococcus, виділених від пацієнтів Дніпропетровської клінічної лікарні ім. І. І. Мечнікова
Authors: Nikulina Y. Y. , Lavrentyeva K. V. , Cherevach N. V. , Sirokvascha О. А. , Vinnikov A. I.
Published: May 2016

It was investigated the biological properties of 494 strains of Staphylococcus genus isolated from pathological material of patients from 15 Departments of Mechnikov Dnipropetrovsk Region Clinical Hospita. All microflora was presented by four bacteria species: Staphylococcus aureus, S. epidermidis, S. haemolyticus and S. saprophyticus. S. aureus was the most extended agent of infections. All bacteria were the most sensitive to linezolid, gentamycin and meropenem.
Ідентифікація термостабільного ентеротоксину Escherichia coli при колібактеріозі телят
Authors: Sukharev Y. S.
Published: May 2016

IFA test-sistem is developed for identification of the heat stable (ST) enterotoxin of Escherichia coli in the calves faeces at different stages of colibacteriosis. The range of its titre makes ≥ 250 ng/ml at the hyperacute stage, at the acute stage – ≥ 500 ng/ml, and at the subacute one– ≥ 1 000 ng/ml. The registered enterotoxin titres can be considered as the diagnostic indices.
Вітамінне забезпечення організму поросят за умов уведення мікроелементної композиції супоросним свиноматкам та поросятам у ранньому постнатальному онтогенезі
Authors: Shapovalov S. О. , Dolgaya M. N.
Published: May 2016

Data on the influence of «Biotam» microelements composition on the level of vitamins A, Е, В2 in blood, liver and muscles of piglets in early postnatal ontogenesis are presented. Significant increase of its concentrations in the animals of the experimental group is shown.
Різноманіття паразитів м’ясоїдних тварин на території м. Дніпропетровськ
Authors: Boyko О. О. , Faly L. I. , Brygadyrenko V. V.
Published: May 2016

In Dnipropetrovsk sity (Ukraine, Dnipropetrovsk region) in carnivorous animals 10 species of parasites (helminths and coccidia) were found: Uncinaria sp., Ancylostoma sp., Dictyocaulus immitis (Nematoda, Strongylata), Strongyloides stercoralis (Nematoda, Rhabditata), Spirocerca lupi (Nematoda, Spirurata), Toxocara canis (Nematoda, Ascaridata), Trichuris vulpis (Nematoda, Trichurata), Dipylidium caninum (Cestoda, Hymenolepidata), Cystoisospora sp. and Toxoplasma gondii (Sporozoa, Coccidia). In soil S. stercoralisand Uncinaria sp. weredominanted. In most carnivorous animals registered in L. Globa park and T. Shevchenko park the S. stercoralisand Uncinaria sp., Cystoisosporasp. and T. gondii were found.
Action of manganese salt on Triticum aestivum
Authors: Tkach E. , Vakerich M. , Nikolaychuk V.
Published: May 2016

Specificneed in manganese is a characteristic feature of all plants. At present time, participation of this element in functioning in a number of processes and structures in the plant organism is proved. Indispensabilityof manganese as a component of plant metabolism is evidenced by death of plants aged 2–4 weeks at absolute exclusion of manganese nutrient medium, and symptoms of disorders at all levels of metabolism due to lack of this element. As opposed to symptoms of deficiency which are specific for every element, the signs of excess are more or less the same. In conditions of gradual increase of the concentration of ions as factors of influence, gradual manifestation of plant organism depression is observed: growth inhibition, root dying and leaf chlorosis, etc. Foliar feeding of grain crops including winter wheat with manganese is very important because they have a great need for such elements as manganese and copper. Efficiencyof the types of foliar feeding is connected with the mechanisms of penetration of manganese into the plant cells. Unlike other metals, manganese can be mobilized by sprouts from seed integument: metal absorption from wheat seeds lasts till the seventh day. That’s why, the aim of our work was to investigate the influence of pre-sowing processing of winter wheat seeds with solutions of different concentrations of manganese sulfate for detection of the optimal concentration and studying of phytotoxic influence of the excess manganese action. Vegetation tests were carried out in the laboratory conditions for performing the studies. Winter wheat seeds were steeped into solutions of manganese sulfate in such concentrations as 0.001%, 0.01%, 0.1%, 0.5% and 1%. After that they were couched in multi-component environment (sod-podzol soil). As a control variant, an experiment without treatment was used. The influence of different concentrations on the growth processes such as seed germination, length of the sprout, weight of the plants and their root system was estimated. It was determined that the optimal concentration of manganese sulfate for the pre-sowing processing was equal to 0.001–0.01%. The critical one, at which the phytotoxic action is manifested in growth depression and decrease of sprout biomass, is the use of 0.5–1.0% solution of manganese sulfate for the pre-sowing seed treatment.
Role of fibronectin under conditions of doxorubicin action
Authors: Shevtsova A. I. , Ushakova G. A.
Published: May 2016

There is no standard as to treatment of anthracycline chemotherapy complications. The reduction of cytotoxic drugs toxicity without weakening of their antitumor action remains relevant. The extracellular matrix which key component is fibronectin is present in all tissues and it continuously undergoes controlled remodeling. So, the purpose of our work was to study the level of fibronectin in the experimental model of doxorubicin-induced cardiomyopathy and effects of this cytostatic and its co-administration with antioxidants of different nature.The level of fibronectin was measured by ELISA using monospecific antibodies against fibronectin (Sigma, USA), secondary anti-IgG labeled with horseradish peroxidase (Sigma, USA) and fibronectin standard (Sigma, USA). The study was conducted on Wistar male rats with weight of 210 ± 50 g which were divided into 4 groups by 8 animals in each group: 1 – control, rats receiving saline i/p; 2 – doxorubicin 1 mg/kg i/p once a week during 4 weeks; 3 – doxorubicin by the same scheme plus 1% 2-oxoglutarate in drinking water during 4 weeks;4 – doxorubicin by the same scheme and korvitin injection 30 min before doxorubicin application once a week during 4 weeks. Obtained data indicate the effect of doxorubicin to decrease in index mass heart in 38% of animals compared to control animals; decrease in total protein concentration by 8% (Р < 0,05) and increase of the level of fibronectin by 67% (P < 0,001) in blood plasma of rats and decrease in the level of fibronectin in the heart extract by 19% (Р < 0,05) under development of doxorubicin-induced cardiotoxicity. Increased fibronectin concentration in blood plasma had strong correlation with decreased total protein concentration in blood (r=0,80) and heart extract (r=0,59) in rats with doxorubicin-induced cardiomiophaty indicating the sensitive reaction of fibronectin to development of metabolic disorders under doxorubicin influence.
Altered balance between proteolysis and antiproteolysis in oncohematologic diseases
Authors: Shaul’ska O. E. , Diachenko L. M. , Nikolayenko-Kamyshova T. P. , Shevtsova A. I.
Published: May 2016

Destruction of malignant cell clones and search for markers of the effectiveness of chemotherapy in patients with hematologic malignancies is an urgent direction of research. The purpose of this paper was to study plasma of patients with various forms of blood tumor, the activity of trypsin-like enzymes, matrix metalloproteinases MMP2 and MMP9, content of α1-proteinase inhibitor and α2-macroglobulin before and after the cytotoxic therapy by anthracycline antibiotics, doxorubicin and daunorubicin. It was established that concentration of inhibitors and activity of trypsin-like enzymes increased in patients with acute myeloid leukemia and multiple myeloma against the backdrop of multidirectional changes of proMMP9. Activity of the latter enzyme was reduced to 0,03±0,01 rel. u. in acute myeloid leukemia, and after chemotherapy it increased 7 times. Reducing level of inhibitors and increasing activity of MMP9 were found in chronic lymphocytic leukemia. The presence of the correlation between the α2-macroglobulin and gelatinase activity in the treatment indicates that the inhibitor is an important mechanism for storing of gelatinоlytic potential. Balance between proteolysis and antiproteolysis depends on the type of proliferating cells and the course of the disease. Indicators of tissue destruction may be an additional criterion for monitoring the stage of blood tumors and efficacy of treatment.
Evaluation of efficiency of using the enzyme preparation «Celloviridin Dx20» in the content of pig feed
Authors: Dejnega A. O. , Lesova V. O. , Anatsky A. S.
Published: May 2016

One of the main problems in the feeding of farm animals is the low degree of digestion and assimilation of nutrients in the feed used in animal production. In the bodies of animals such as pigs and poultry enzymes and microflora which are necessary for breaking down cellulose and other polysaccharides of vegetable raw materials are absent, therefore they not only fail to be digested in the gastrointestinal tract, but also obstruct access of other digestive enzymes to the other feed components, in particular intracellular proteins. The only way to solve this problem is deliberate introduction of enzymes into food. Depending on the type and composition of the feed, amylolytic, proteolytic, cellulolytic enzyme preparations are used. The purpose of this work is to assess the effect of the enzyme preparation "Celloviridin Dx20" as a fodder component on the growth and biochemical parameters of young pigs. For this purpose, a scientific and economic experiment on feeding young pigs was conducted at the agro-industrial farm«Niva» (Novonikolaevka village, Dnipropetrovsk region), in which the enzyme preparation «Celloviridin Dx20», which promotes the breakdown of plant cell polysaccharides (cellulose, xylans) was introduced to a standard feed mixture used in swine husbandry. The composition of the ration consisted of 60% barley, 20% wheat and 20% of the protein-vitamin-mineral complex «ShenPigStart». The results of the experiment showed that the introduction into the feed mixture of the enzyme preparation at 100 g per ton helps to increase the body weight of pigs by 11.6% compared to the control, can increase the digestion rate of fibre (13.8%), protein and fat. These results can be explained by the mechanism of action of the enzyme complex, which consists in the hydrolysis of polysaccharides of plant cell walls in the feed in the digestive tract of pigs, the formation of digestable polysaccharides and the release of additional quantities of intracellular proteins. The result of these phenomena is also a positive trend in feed nitrogen assimilation in animals of the experimental group: a 19% decrease in the amount of physiological secretions and a 12.5% increase in nitrogen use. At the same time hematology (hemoglobin, erythrocytes, leukocytes), calcium and phosphorus metabolism remained unchanged. This shows that the preparation used does not accumulate in the body and gradually loses enzymatic activity, and under the influence of the pigs’ stomach proteases it is broken down into separate amino acids which are absorbed by the animals. The resulting stimulatory effect of using "Celloviridin Dх20" has not only physiological but also economic importance, as it helps reduce the time for the pigs to reach slaughter weight (close to 100 kg) by 11 days, and consequently, reduces feed intake and its costs in rearing pigs on farms. Therefore, it is advisable to use "Celloviridin Dх20" in swine husbandry.
Molecular and cellular mechanisms of profile changes of charged blood plasma free oligosaccharides in myeloproliferative disorders
Authors: Pismenetskaya I. U. , Butters T. D.
Published: May 2016

Free oligosaccharides (FOS) are unbound to proteins or lipids structural analogs of their glycans. FOS appear as by-products of endoplasmic reticulum synthesis, cell control folding with endoplastic reticulum-associated degradation and lysosomal/endosomal breakdown of glycoconjugates. They may be either neutral or negatively charged depending on the way of their formation. Charged FOS appear during degradation of glycoconjugates in the lysosomal/endosomal system and are natural substrates for lysosomal sialidase-1. FOS are formed inside the cell but some of them can get into the extracellular space, and then into the blood and urine, where both neutral and charged structures were found. Secretion of charged FOS outside of the cell is most likely to be caused by the lysosomal exocytosis. The activity of neuraminidase-1 is known to be connected with the intensity of the lysosomal exocytosis. In our previous studies, it was found that HPLC-profiles of charged FOS were specifically changed in acute and chronic myeloproliferative blood disorders. The objective of this work was to analyze the molecular and cellular mechanisms of these changes and to test the hypothesis of their association with the activity change of lysosomal neuraminidase-1. Plasma samples of patients with acute and chronic leukaemia – polycytaemia vera, chronic idiopathic myelofibrosis, hypoplastic anaemia, myelodysplastic syndrome with transformation, acute lymphatic and acute myelomonocytic leukaemia – were collected for investigation. Plasma samples of practically healthy volunteers were obtained and used for comparison. After plasma deproteinization and FOS purification the oligosaccharides were labelled with anthranilic acid (2-AA), separated into the neutral and charged fractions with QAE Sephadex (Q25-120) chromatography and analysed using high-performance liquid chromatography (HPLC). Glucose unit values were determined following comparison with a 2-AA-labelled glucose oligomer ladder derived from a partial hydrolysate of dextran as an external standard. The data were collected and processed using Empower software. The charged FOS were digested with the sialidase from Arthrobacter ureafaciens. 2-AA – labelled free oligosaccharides from transferrin were used as an external standard for the structure decoding. In this paper, the changes in neraminidase-1 activity was first demonstrated on natural substrates, free oligosaccharides, in vivo. Chromatographic profiles of charged plasma FOS of patients with acute and chronic hematological malignancies revealed decreasing of neuraminidase-1 activity and increasing of the lysosomal exocytosis. Thus, chromatographic profiles of charged plasma FOS appeared to be a sensitive parameter of the lysosomal/endosomal status in normal or pathological states and to open up new prospects for their applications to the development of anti-cancer drugs designed to block the work of the lysosomal/endosomal system and monitoring of their action.