bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure Legends from Thyroid Hormone Regulation of miR-21 Enhances Migration and Invasion of Hepatoma
Authors: Huang Ya-Hui , Lin Yang-Hsiang , Chi Hsiang-Cheng , Liao Chen-Hsin , Liao Chia-Jung , Wu Sheng-Ming , Chen Cheng-Yi , Tseng Yi-Hsin , Tsai Chung-Ying , Lin Sheng-Yen , Hung Yu-Ting , Wang Chih-Jen , Lin Crystal D. , Lin Kwang-Huei
Published: April 2023

PDF - 119K, Legends for Figures 1-8.
Supplementary Figure 5 from Thyroid Hormone Regulation of miR-21 Enhances Migration and Invasion of Hepatoma
Authors: Huang Ya-Hui , Lin Yang-Hsiang , Chi Hsiang-Cheng , Liao Chen-Hsin , Liao Chia-Jung , Wu Sheng-Ming , Chen Cheng-Yi , Tseng Yi-Hsin , Tsai Chung-Ying , Lin Sheng-Yen , Hung Yu-Ting , Wang Chih-Jen , Lin Crystal D. , Lin Kwang-Huei
Published: April 2023

PDF - 38K, Sequence of primary miR-21 promoter region (-3000/+1).
Supplementary Figure 4 from Thyroid Hormone Regulation of miR-21 Enhances Migration and Invasion of Hepatoma
Authors: Huang Ya-Hui , Lin Yang-Hsiang , Chi Hsiang-Cheng , Liao Chen-Hsin , Liao Chia-Jung , Wu Sheng-Ming , Chen Cheng-Yi , Tseng Yi-Hsin , Tsai Chung-Ying , Lin Sheng-Yen , Hung Yu-Ting , Wang Chih-Jen , Lin Crystal D. , Lin Kwang-Huei
Published: April 2023

PDF File - 47K, Effect of T3 on primary miR-21 in HepG2-TR�1 cells.
Supplementary Figure 2 from Thyroid Hormone Regulation of miR-21 Enhances Migration and Invasion of Hepatoma
Authors: Huang Ya-Hui , Lin Yang-Hsiang , Chi Hsiang-Cheng , Liao Chen-Hsin , Liao Chia-Jung , Wu Sheng-Ming , Chen Cheng-Yi , Tseng Yi-Hsin , Tsai Chung-Ying , Lin Sheng-Yen , Hung Yu-Ting , Wang Chih-Jen , Lin Crystal D. , Lin Kwang-Huei
Published: April 2023

PDF File - 46K, Endogenous protein expression of TR�1 in various types of hepatoma cell lines.
Supplementary Data 3 from Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from T-cell–Mediated Lysis
Authors: Akalay Intissar , Janji Bassam , Hasmim Meriem , Noman Muhammad Zaeem , André Fabrice , De Cremoux Patricia , Bertheau Philippe , Badoual Cécile , Vielh Philippe , Larsen Annette K. , Sabbah Michèle , Tan Tuan Zea , Keira Joan Herr , Ying Hung Nicole Tsang , Thiery Jean Paul , Mami-Chouaib Fathia , Chouaib Salem
Published: April 2023

PDF file - 317K, List of EMT- and autophagy-related differentially expressed genes in SNAI1- and SNAI1-6SA-expressing MCF-7 cells
Supplementary Figure 1 from Thyroid Hormone Regulation of miR-21 Enhances Migration and Invasion of Hepatoma
Authors: Huang Ya-Hui , Lin Yang-Hsiang , Chi Hsiang-Cheng , Liao Chen-Hsin , Liao Chia-Jung , Wu Sheng-Ming , Chen Cheng-Yi , Tseng Yi-Hsin , Tsai Chung-Ying , Lin Sheng-Yen , Hung Yu-Ting , Wang Chih-Jen , Lin Crystal D. , Lin Kwang-Huei
Published: April 2023

PDF File - 116K, Full-length 3'UTR sequence of TIAM1 and MSH2.
Supplementary Figure Legends from Myeloid WNT7b Mediates the Angiogenic Switch and Metastasis in Breast Cancer
Authors: Yeo Eun-Jin , Cassetta Luca , Qian Bin-Zhi , Lewkowich Ian , Li Jiu-feng , Stefater James A. , Smith April N. , Wiechmann Lisa S. , Wang Yihong , Pollard Jeffrey W. , Lang Richard A.
Published: April 2023

PDF file - 1107K
Supplementary Figure 1 from Myeloid WNT7b Mediates the Angiogenic Switch and Metastasis in Breast Cancer
Authors: Yeo Eun-Jin , Cassetta Luca , Qian Bin-Zhi , Lewkowich Ian , Li Jiu-feng , Stefater James A. , Smith April N. , Wiechmann Lisa S. , Wang Yihong , Pollard Jeffrey W. , Lang Richard A.
Published: April 2023

PDF file - 2729K, S1: Flow sorting of human and mouse tumor-associated macrophages.
Supplementary Methods from Oncolytic Vaccinia Virus Disrupts Tumor-Associated Vasculature in Humans
Authors: Breitbach Caroline J. , Arulanandam Rozanne , De Silva Naomi , Thorne Steve H. , Patt Richard , Daneshmand Manijeh , Moon Anne , Ilkow Carolina , Burke James , Hwang Tae-Ho , Heo Jeong , Cho Mong , Chen Hannah , Angarita Fernando A. , Addison Christina , McCart J. Andrea , Bell John C. , Kirn David H.
Published: April 2023

Supplementary Methods PDF file - 44K, GLP toxicology study, In vivo imaging and mouse immunohistochemical analyses
Supplementary Figure 4 from Oncolytic Vaccinia Virus Disrupts Tumor-Associated Vasculature in Humans
Authors: Breitbach Caroline J. , Arulanandam Rozanne , De Silva Naomi , Thorne Steve H. , Patt Richard , Daneshmand Manijeh , Moon Anne , Ilkow Carolina , Burke James , Hwang Tae-Ho , Heo Jeong , Cho Mong , Chen Hannah , Angarita Fernando A. , Addison Christina , McCart J. Andrea , Bell John C. , Kirn David H.
Published: April 2023

Supplementary Figure 4 PDF file - 69K, Day 5 enhancement waterfall plot
Supplementary Figure S4 from Adjuvants That Improve the Ratio of Antigen-Specific Effector to Regulatory T Cells Enhance Tumor Immunity
Authors: Perret Rachel , Sierro Sophie R. , Botelho Natalia K. , Corgnac Stéphanie , Donda Alena , Romero Pedro
Published: April 2023

Supplementary Figure S4. Draining lymph node T cell responses following vaccination of tumor-bearing mice
Supplementary Figure 3 from Identification of Inherited Genetic Variations Influencing Prognosis in Early-Onset Breast Cancer
Authors: Rafiq Sajjad , Tapper William , Collins Andrew , Khan Sofia , Politopoulos Ioannis , Gerty Sue , Blomqvist Carl , Couch Fergus J. , Nevanlinna Heli , Liu Jianjun , Eccles Diana
Published: April 2023

PDF file - 53K, Regional plot of p-values arising from cox-proportional hazard models, 250 kb either side of the rs3785982 variant in stage-1. P-values are from imputed data alone.
Supplementary Figure 4 from Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy
Authors: Mok Stephen , Koya Richard C. , Tsui Christopher , Xu Jingying , Robert Lídia , Wu Lily , Graeber Thomas G. , West Brian L. , Bollag Gideon , Ribas Antoni
Published: April 2023

PDF file - 490K, Effects of PLX3397 on the distribution of adoptively transferred lymphocytes in the OT-1 ACT model.
Supplementary Figure 1 from Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy
Authors: Mok Stephen , Koya Richard C. , Tsui Christopher , Xu Jingying , Robert Lídia , Wu Lily , Graeber Thomas G. , West Brian L. , Bollag Gideon , Ribas Antoni
Published: April 2023

PDF file - 32K, Expression of CSF-1 by SM1.
Supplementary Table 6 from Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
Authors: Lee Genee Y. , Haverty Peter M. , Li Li , Kljavin Noelyn M. , Bourgon Richard , Lee James , Stern Howard , Modrusan Zora , Seshagiri Somasekar , Zhang Zemin , Davis David , Stokoe David , Settleman Jeffrey , de Sauvage Frederic J. , Neve Richard M.
Published: April 2023

XLSX file - 29K, Analysis of expression (cancer versus normal) and association with outcome for PSMB4 and SHMT2.
Supplementary Table 5 from Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
Authors: Lee Genee Y. , Haverty Peter M. , Li Li , Kljavin Noelyn M. , Bourgon Richard , Lee James , Stern Howard , Modrusan Zora , Seshagiri Somasekar , Zhang Zemin , Davis David , Stokoe David , Settleman Jeffrey , de Sauvage Frederic J. , Neve Richard M.
Published: April 2023

XLSX file - 39K, Gene copy number and ecpression (by Affymetrix and TaqMan) in cell lines used to screen for hits.
Supplementary Table 4 from Notch3 Pathway Alterations in Ovarian Cancer
Authors: Hu Wei , Liu Tao , Ivan Cristina , Sun Yunjie , Huang Jie , Mangala Lingegowda S. , Miyake Takahito , Dalton Heather J. , Pradeep Sunila , Rupaimoole Rajesh , Previs Rebecca A. , Han Hee Dong , Bottsford-Miller Justin , Zand Behrouz , Kang Yu , Pecot Chad V. , Nick Alpa M. , Wu Sherry Y. , Lee Ju-Seog , Sehgal Vasudha , Ram Prahlad , Liu Jinsong , Tucker Susan L. , Lopez-Berestein Gabriel , Baggerly Keith A. , Coleman Robert L. , Sood Anil K.
Published: April 2023

PDF file - 65K, Microarray Analysis of Significantly Down- regulated Genes in OVCAR3 cells With or Without Notch3 Silencing.
Supplementary Methods from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: April 2023

PDF file - 155KB
Supplementary Figure 2 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

PDF file - 766K, TaqMan validation of RNAseq data. Taqman Fold Change was calculated for three genes (PTN, SYNM, and TMSB10) and plotted against FPKM values.
Supplementary Methods from Selection of Personalized Patient Therapy through the Use of Knowledge-Based Computational Models That Identify Tumor-Driving Signal Transduction Pathways
Authors: Verhaegh Wim , van Ooijen Henk , Inda Márcia A. , Hatzis Pantelis , Versteeg Rogier , Smid Marcel , Martens John , Foekens John , van de Wiel Paul , Clevers Hans , van de Stolpe Anja
Published: April 2023

PDF file - 174KB, Details of the modeling approach, selected genes and probesets, and additional results. Also includes supplementary references.
Supplementary Figure 7 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: April 2023

PDF file - 3369K, JAM-B is expressed on BM endothelial cells of NOD/SCID mice
Supplementary Methods, Figure Legend, Table 1, Figures 1-8 from Midkine Promotes Neuroblastoma through Notch2 Signaling
Authors: Kishida Satoshi , Mu Ping , Miyakawa Shin , Fujiwara Masatoshi , Abe Tomoyuki , Sakamoto Kazuma , Onishi Akira , Nakamura Yoshikazu , Kadomatsu Kenji
Published: April 2023

PDF file - 7746K, Supplementary Table S1. Sequence of primers for PCR experiments Supplementary Figure S1. mRNA expressions in the SMG of MYCN Tg mice Supplementary Figure S2. MK expression in the growing tumors of MYCN Tg mice Supplementary Figure S3. SPR assay with the RNA aptamer Apt-nc Supplementary Figure S4. In vivo AP assay with TNB1 cells Supplementary Figure S5. Soft agar assay with TNB1, YT-nu and LNCap cells. Supplementary Figure S6. The overview of TNB1 xenograft tumors Supplementary Figure S7. Soft agar and xenograft experiments with YT-nu cells Supplementary Figure S8. The attenuation of Notch2 signaling in Apt-1-treated YT-nu xenograft tumors
Supplementary Figure S4 from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: April 2023

Supplementary Figure S4 PDF file - 1618K, Twenty-eight surface markers associated with activation, cytotoxicity, and differentiation were analyzed by flow cytometry on the gated NK population from the PBMC of patients with cancer on Day 0 (rest, pre-activation) and Day 11 (activation, post-expansion)
Supplementary Table 1 from FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57
Authors: Cuevas Rolando , Korzeniewski Nina , Tolstov Yanis , Hohenfellner Markus , Duensing Stefan
Published: April 2023

PDF file - 55K, SiRNA library used for the centriole overduplication screen.
Supplementary Figure Legend from Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer
Authors: Khalaileh Abed , Dreazen Avigail , Khatib Areej , Apel Roy , Swisa Avital , Kidess-Bassir Norma , Maitra Anirban , Meyuhas Oded , Dor Yuval , Zamir Gideon
Published: April 2023

PDF file - 66K
Supplementary Movie S2 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: April 2023

Supplementary Movie S2 AVI file - 1069K, GFP-labeled MDA-MB-231 cells stably expressing Arkadia C937A were seeded on top of a layer of HUVEC cells, and images were acquired every 5 min using a Plan apochromat 20x 0.8 objective on a Zeiss LSM 780 confocal microscope. The movie was created using Imaris software (Bitplane)
Supplementary Figure 1 from RNA Trafficking by Acute Myelogenous Leukemia Exosomes
Authors: Huan Jianya , Hornick Noah I. , Shurtleff Matthew J. , Skinner Amy M. , Goloviznina Natalya A. , Roberts Charles T. , Kurre Peter
Published: April 2023

PDF file - 2.9MB, The detection of IGF-1R in HL-60 cell and vesicle lysates by Western blot
Supplementary Legends from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: April 2023

Supplementary Legends PDF File - 120K, Legends for Supplementary Figures, Table, and Movies
Supplementary Figure S6 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: April 2023

Supplementary Figure S6 PDF File - 35K, Validation of RNA-seq data by qPCR
Supplementary Figure S1 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: April 2023

Supplementary Figure S1 PDF File - 109K, A mutation in the Arkadia gene in NCI-H460 cells produces a truncated protein
Supplementary Figure 10 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: April 2023

PDF file - 46KB, NOS1 and CXCL14 mRNA expression correlates in human breast cancer data sets.
Supplementary Table 2 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: April 2023

PDF file - 57K, COX regression multivariate analysis for the predictive factor biochemical recurrence (BCR).
Supplementary Table 1 from Neuregulin Autocrine Signaling Promotes Self-Renewal of Breast Tumor-Initiating Cells by Triggering HER2/HER3 Activation
Authors: Lee Cleo Yi-Fang , Lin Yuan , Bratman Scott V. , Feng Weiguo , Kuo Angera H. , Scheeren Ferenc A. , Engreitz Jesse M. , Varma Sushama , West Robert B. , Diehn Maximilian
Published: April 2023

PDF file - 52K, Clinical information for BCA patient-derived xenografts.
Supplementary Figure 1 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: April 2023

PDF file - 68K, Localization of the CHD1 FISH probe made from two BAC clones relative to the CHD1 gene.
Supplementary Methods and Figure Legends from PARI Overexpression Promotes Genomic Instability and Pancreatic Tumorigenesis
Authors: O'Connor Kevin W. , Dejsuphong Donniphat , Park Eunmi , Nicolae Claudia M. , Kimmelman Alec C. , D'Andrea Alan D. , Moldovan George-Lucian
Published: April 2023

PDF file - 62K, Supplemental Materials and Methods, including: Antibodies, Gene knockdown by siRNA, and Histology.
Supplementary Figures 1 - 11 from PARI Overexpression Promotes Genomic Instability and Pancreatic Tumorigenesis
Authors: O'Connor Kevin W. , Dejsuphong Donniphat , Park Eunmi , Nicolae Claudia M. , Kimmelman Alec C. , D'Andrea Alan D. , Moldovan George-Lucian
Published: April 2023

PDF file - 2404K, Supplementary Figures 1-11; Supplementary Figure 1: Representative micrographs showing a decrease in IR-induced RAD51 foci in PARI-overexpressing 8988T and CAPAN2 cells. Supplementary Figure 2: PARI-overexpressing pancreatic cancer cell line 8988T is hypersensitive to PARP inhibitor ABT-888. Supplementary Figure 3: SupF-based mutagenesis assay showing increased point mutations in 293T cells overexpressing Myc-PARI at high levels. Supplementary Figure 4: Analysis of chromosome morphology in metaphase spreads of 8988T cells, showing that PARI knockdown reduces chromosomal aberrations following exposure to 20ng/ml MMC. Supplementary Figure 5: PARI depletion reduces viability of PARI-overexpressing cells (CAPAN2), but does not affect the cells that do not overexpress it (CAPAN1, HeLa, 293T). Supplementary Figure 6: PARI knockdown leads to a significant increase in the S-phase fraction. Supplementary Figure 7: FACS analysis of 8988T cells treated with HU, followed by release in fresh media. Supplementary Figure 8: PARI depletion in CAPAN2 (pancreatic cancer cells overexpressing PARI) results in HU sensitivity. Supplementary Figure 9: Depletion of PARI by shRNA decreases cellular proliferation when grown in the presence of 20μg/ml doxycyline. Supplementary Figure 10: H&E stain of paraffin-embedded slides showing increased necrosis in xenograft tumors originating from PARI-depleted 8988T cells. Supplementary Figure 11: Model of PARI-dependent DNA repair regulation in pancreatic cancer cells.
Supplementary Materials and Methods from β-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
Authors: Mokkapati Sharada , Niopek Katharina , Huang Le , Cunniff Kegan J. , Ruteshouser E. Cristy , deCaestecker Mark , Finegold Milton J. , Huff Vicki
Published: April 2023

PDF file - 90KB
Supplementary Materials and Methods, Table 1 from Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15
Authors: Bruzzese Francesca , Hägglöf Christina , Leone Alessandra , Sjöberg Elin , Roca Maria Serena , Kiflemariam Sara , Sjöblom Tobias , Hammarsten Peter , Egevad Lars , Bergh Anders , Östman Arne , Budillon Alfredo , Augsten Martin
Published: April 2023

PDF file - 166KB, Supplementary Table 1. Human and murine primer.
Supplementary Figure 3 from β-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
Authors: Mokkapati Sharada , Niopek Katharina , Huang Le , Cunniff Kegan J. , Ruteshouser E. Cristy , deCaestecker Mark , Finegold Milton J. , Huff Vicki
Published: April 2023

PDF file - 1806KB, Wnt pathway and proliferation in livers of littermate control adult mice and one month old Tg-beta-cats mice.
Supplementary Figure 1 from β-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
Authors: Mokkapati Sharada , Niopek Katharina , Huang Le , Cunniff Kegan J. , Ruteshouser E. Cristy , deCaestecker Mark , Finegold Milton J. , Huff Vicki
Published: April 2023

PDF file - 1419KB, Characterization of CreERTM-GFP+ cells of fetal liver.
Supplementary Table 1 from Enhancement of Antitumor Immunity in Lung Cancer by Targeting Myeloid-Derived Suppressor Cell Pathways
Authors: Sawant Anandi , Schafer Cara C. , Jin Tong Huan , Zmijewski Jaroslaw , Tse Hubert M. , Roth Justin , Sun Zhihuan , Siegal Gene P. , Thannickal Victor J. , Grant Stefan C. , Ponnazhagan Selvarangan , Deshane Jessy S.
Published: April 2023

PDF file - 18K, Antibodies used for characterization of Immune Cell Phenotypes.
Supplementary Figures 1 - 7 from Enhancement of Antitumor Immunity in Lung Cancer by Targeting Myeloid-Derived Suppressor Cell Pathways
Authors: Sawant Anandi , Schafer Cara C. , Jin Tong Huan , Zmijewski Jaroslaw , Tse Hubert M. , Roth Justin , Sun Zhihuan , Siegal Gene P. , Thannickal Victor J. , Grant Stefan C. , Ponnazhagan Selvarangan , Deshane Jessy S.
Published: April 2023

PDF file - 381K, The phenotype of MDSC in the lung and spleen from lung cancer challenged mice (S1); Reduced tumor burden in mice from Gem and SODmim+Gem therapy groups (S2); Combination therapy reduced infiltration of neutrophils but not macrophages in tumor (S3); Combination therapy was efficient in reducing tumor growth in catalase deficient mice by decreasing MDSC infiltration and improving the memory CD8+ T cell response (S4); Persistent memory CD8+ T cell subsets expand following re-encounter with i.v. challenged LLC cells (S5); Adoptively transferred memory cells persist and reduce MDSC infiltration and tumor burden in LLC-rechallenged recipient mice (S6); Adoptively transferred memory cells expand upon encounter with tumor cells (S7).
Supplementary Figure 5 from A Preclinical Assay for Chemosensitivity in Multiple Myeloma
Authors: Khin Zayar P. , Ribeiro Maria L.C. , Jacobson Timothy , Hazlehurst Lori , Perez Lia , Baz Rachid , Shain Kenneth , Silva Ariosto S.
Published: April 2023

PDF file - 677K, In vitro melphalan chemosensitivity of three MM patients.
Supplementary Figures 1 - 7, Table 1 from HMMR Maintains the Stemness and Tumorigenicity of Glioblastoma Stem-like Cells
Authors: Tilghman Jessica , Wu Hao , Sang Yingying , Shi Xiaohai , Guerrero-Cazares Hugo , Quinones-Hinojosa Alfredo , Eberhart Charles G. , Laterra John , Ying Mingyao
Published: April 2023

PDF file - 1756KB, Supplemental Figure 1: Representative results show tumor specimens in GBM tissue array stained with rabbit IgG as the primary antibody. Supplemental Figure 2. HMMR expression in human gliomas. Supplemental Figure 3. HMMR knockdown inhibits cell proliferation. Supplemental Figure 4. HMMR immunohistochemistry (IHC) staining on tumors derived from GBM1A cells infected with HMMR shRNA1 or non-targeting (NT) control shRNA. Supplemental Figure 5. Limiting dilution tumor initiation assay. Supplemental Figure 6. Red and green GBM neurospheres for in vivo dual-color competition assay. Supplemental Figure 7. The correlation between HMMR and OLIG2 expression in human GBM specimens. Supplemental Table 1. HMMR shRNA sequences and qRT-PCR primer sequences.
Supplementary Table S5 from Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma
Authors: Zhang Keqiang , Chu Kevin , Wu Xiwei , Gao Hanlin , Wang Jinhui , Yuan Yate-Ching , Loera Sofia , Ho Kimberley , Wang Yafan , Chow Warren , Un Frank , Chu Peiguo , Yen Yun
Published: April 2023

Supplementary Table S5 PDF file 57K, Relative gene copy number determined by qPCR analysis (ratio to adjacent normal tissue) of selected eight genes located on chromosome 12q13-15 of individual DDLS
Supplementary Figure 3 from Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity
Authors: Risinger A.L. , Li J. , Bennett M.J. , Rohena C.C. , Peng J. , Schriemer D.C. , Mooberry S.L.
Published: April 2023

PDF file - 215K, High magnification electron micrographs (20,000x and 50,000x) of microtubules formed in the presence of 2 mg/ml tubulin with 10 microM AJ, PTX or LAU after chilling the microtubules at -20 degrees C for 30 min.
Supplementary Tables from ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Authors: Molina Angie , Velot Lauriane , Ghouinem Lydia , Abdelkarim Mohamed , Bouchet Benjamin Pierre , Luissint Anny-Claude , Bouhlel Imène , Morel Marina , Sapharikas Elène , Di Tommaso Anne , Honoré Stéphane , Braguer Diane , Gruel Nadège , Vincent-Salomon Anne , Delattre Olivier , Sigal-Zafrani Brigitte , André Fabrice , Terris Benoit , Akhmanova Anna , Di Benedetto Mélanie , Nahmias Clara , Rodrigues-Ferreira Sylvie
Published: April 2023

Supplementary Tables XLS file - 200K, Table SI : breast tumors and normal samples data; Table SII: MTUS1 expression level in invasive breast tumors collected at Institut Gustave Roussy; Table SIII: Time-course of metastasis formation
Movie 7 from ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Authors: Molina Angie , Velot Lauriane , Ghouinem Lydia , Abdelkarim Mohamed , Bouchet Benjamin Pierre , Luissint Anny-Claude , Bouhlel Imène , Morel Marina , Sapharikas Elène , Di Tommaso Anne , Honoré Stéphane , Braguer Diane , Gruel Nadège , Vincent-Salomon Anne , Delattre Olivier , Sigal-Zafrani Brigitte , André Fabrice , Terris Benoit , Akhmanova Anna , Di Benedetto Mélanie , Nahmias Clara , Rodrigues-Ferreira Sylvie
Published: April 2023

Movie 7 AVI file - 629K, Time-lapse videomicroscopy of wound healing assay in GFP-D2-transiently transfected D3H2LN cells
Movie 2 from ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Authors: Molina Angie , Velot Lauriane , Ghouinem Lydia , Abdelkarim Mohamed , Bouchet Benjamin Pierre , Luissint Anny-Claude , Bouhlel Imène , Morel Marina , Sapharikas Elène , Di Tommaso Anne , Honoré Stéphane , Braguer Diane , Gruel Nadège , Vincent-Salomon Anne , Delattre Olivier , Sigal-Zafrani Brigitte , André Fabrice , Terris Benoit , Akhmanova Anna , Di Benedetto Mélanie , Nahmias Clara , Rodrigues-Ferreira Sylvie
Published: April 2023

Movie 2 AVI file - 2424K, Time-lapse videomicroscopy of wound healing assay using GFP-ATIP3-transfected D3H2LN clone (Cl3)
Supplementary Figure 5 from Parathyroid Hormone–Related Protein Drives a CD11b+Gr1+ Cell–Mediated Positive Feedback Loop to Support Prostate Cancer Growth
Authors: Park Serk In , Lee Changki , Sadler W. David , Koh Amy J. , Jones Jacqueline , Seo Jung Won , Soki Fabiana N. , Cho Sun Wook , Daignault Stephanie D. , McCauley Laurie K.
Published: April 2023

PDF file - 3119K, Supplemental Fig. 5 Alterations in the bone marrow after a single rPTHrP administration.
Supplementary Table 2 from Hyperpolarized 13C-Pyruvate Magnetic Resonance Reveals Rapid Lactate Export in Metastatic Renal Cell Carcinomas
Authors: Keshari Kayvan R. , Sriram Renuka , Koelsch Bertram L. , Van Criekinge Mark , Wilson David M. , Kurhanewicz John , Wang Zhen J.
Published: April 2023

PDF file-56KB, Analysis of hyperpolarized dynamics in bioreactors containing perfused HK2, UMRC6 and UOK262 cells at a flow rate of 2.5ml/min.
Supplementary Table 2 from Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment
Authors: Dijkgraaf Eveline M. , Heusinkveld Moniek , Tummers Bart , Vogelpoel Lisa T.C. , Goedemans Renske , Jha Veena , Nortier Johan W.R. , Welters Marij J.P. , Kroep Judith R. , van der Burg Sjoerd H.
Published: April 2023

PDF file - 68K, Cancer cell lines were treated with 2μg/mL cisplatin or 20μg/mL carboplatin for 16h. Then, cells were washed and medium was replaced. TSN were analyzed after 24h for cytokine production. Mean of 3 experiments. Cervical cancer cell lines; CSCC1, CASKI, HELA, CC8 and CSCC7. Ovarian cancer cell lines; SKOV3, OVCAR3, A2780, COV413B and CAOV3. No significant changes were observed. nd: not detectable; blanks: not tested.
Supplementary Table 1 from Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment
Authors: Dijkgraaf Eveline M. , Heusinkveld Moniek , Tummers Bart , Vogelpoel Lisa T.C. , Goedemans Renske , Jha Veena , Nortier Johan W.R. , Welters Marij J.P. , Kroep Judith R. , van der Burg Sjoerd H.
Published: April 2023

PDF file - 50K, Percentage of cells expressing the different phenotypic markers on cultured APC as measured by flow cytometry. Indicated are the mean percentage of 3 experiments with standard deviation of 3 different donors used. CD: Cluster of differentiation. The percentage of cells expressing the indicated markers after monocytes were differentiated in the presence of M2-TSN and APC-TSN were compared with mo-DC by unpaired t-test. Bold reflects p < 0.01. Cervical cancer cell lines; CSCC1, CASKI, HELA, CC8 and CSCC7. Ovarian cancer cell lines; SKOV3, OVCAR3, A2780, COV413B and CAOV3.
Supplementary Figures 1 - 7 from Targeting the Deregulated Spliceosome Core Machinery in Cancer Cells Triggers mTOR Blockade and Autophagy
Authors: Quidville Virginie , Alsafadi Samar , Goubar Aïcha , Commo Frédéric , Scott Véronique , Pioche-Durieu Catherine , Girault Isabelle , Baconnais Sonia , Le Cam Eric , Lazar Vladimir , Delaloge Suzette , Saghatchian Mahasti , Pautier Patricia , Morice Philippe , Dessen Philippe , Vagner Stéphan , André Fabrice
Published: April 2023

PDF file - 272K, Supplemental figure S1: Correlation analysis between proliferation marker MIK67 and the spliceosome-related genes Supplemental figure S2: Expression of the indicated spliceosomal components in SNRPE or SNRPD1-depleted cells. Supplemental figure S3: Effect of siRNA-mediated depletion of SNRPE or SNRPD1 on cell viability in additional breast, melanoma and lung tumoral cell lines Supplemental figure S4: Correlation analysis between the proliferation rate of all tested cell lines tested and their sensitivity to SNRPE or SNRPD1 depletion Supplemental figure S5: Apoptosis detection in SKBr-3 cell line following SNRPD1 depletion Supplemental figure S6: Genes whose initial exon expression is modulated by SNRPE. Supplemental figure S7: Expression of GUSB and RPLPO control genes in SNRPE-depleted cells treated or not with cycloheximide
Supplementary Figure Legend from Loss of TGF-β Adaptor β2SP Activates Notch Signaling and SOX9 Expression in Esophageal Adenocarcinoma
Authors: Song Shumei , Maru Dipen M. , Ajani Jaffer A. , Chan Chia-Hsin , Honjo Soichiro , Lin Hui-Kuan , Correa Arlene , Hofstetter Wayne L. , Davila Marta , Stroehlein John , Mishra Lopa
Published: April 2023

PDF file - 54K
Supplementary Figures 1 - 3 from Dysregulation of Cholesterol Homeostasis in Human Prostate Cancer through Loss of ABCA1
Authors: Lee Byron H. , Taylor Margaret G. , Robinet Peggy , Smith Jonathan D. , Schweitzer Jessica , Sehayek Ephraim , Falzarano Sara M. , Magi-Galluzzi Cristina , Klein Eric A. , Ting Angela H.
Published: April 2023

PDF file - 339K, S1. Validation of custom rabbit anti-ABCA1 antibody. S2. Additional ABCA1 bisulfite sequencing validation in PrEC and LNCaP cells. S3. DNA methylation patterns at the ABCG1 locus.
Supplementary Figure 4 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells
Authors: Jia Jinping , Bosley Allen D. , Thompson Abbey , Hoskins Jason W. , Cheuk Adam , Collins Irene , Parikh Hemang , Xiao Zhen , Ylaya Kris , Dzyadyk Marta , Cozen Wendy , Hernandez Brenda Y. , Lynch Charles F. , Loncarek Jadranka , Altekruse Sean F. , Zhang Lizhi , Westlake Christopher J. , Factor Valentina M. , Thorgeirsson Snorri , Bamlet William R. , Hewitt Stephen M. , Petersen Gloria M. , Andresson Thorkell , Amundadottir Laufey T.
Published: April 2023

PDF file - 30KB, Expression of MYH9 and MYH10 in PANC-1 stable cell lines by RT-qPCR showing higher RNA expression of MYH9 (red) as compared to MYH10 (blue) in PANC1-vo and PANC1-CLPTM1L stable cell lines.
Supplementary Material from Characterization of a Novel PERK Kinase Inhibitor with Antitumor and Antiangiogenic Activity
Authors: Atkins Charity , Liu Qi , Minthorn Elisabeth , Zhang Shu-Yun , Figueroa David J. , Moss Katherine , Stanley Thomas B. , Sanders Brent , Goetz Aaron , Gaul Nathan , Choudhry Anthony E. , Alsaid Hasan , Jucker Beat M. , Axten Jeffrey M. , Kumar Rakesh
Published: April 2023

Supplementary Material PDF file - 147K, Supplementary Methods: Immunohistochemistry and magnetic resonance imaging. Supplementary Table 1: Kinase selectivity profiling of GSK2656157. Supplementary Table 2: Gene list for Human UPR array
Supplementary Table 7 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

XLSX file - 13KB, Association between AR, RUNX2 and SNAI2 in clinical samples.
Supplementary Methods from API5 Confers Tumoral Immune Escape through FGF2-Dependent Cell Survival Pathway
Authors: Noh Kyung Hee , Kim Seok-Ho , Kim Jin Hee , Song Kwon-Ho , Lee Young-Ho , Kang Tae Heung , Han Hee Dong , Sood Anil K. , Ng Joanne , Kim Kwanghee , Sonn Chung Hee , Kumar Vinay , Yee Cassian , Lee Kyung-Mi , Kim Tae Woo
Published: April 2023

PDF file - 207KB
Supplementary Table 4 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

XLSX file - 31KB, Type II DHT and DHT dox-induced gene expression values from the microarray.
Supplementary Table 2 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

XLSX file - 9KB, Clinical characteristics of the TMA cohort.
Supplementary Figure Legend from Doxorubicin Eliminates Myeloid-Derived Suppressor Cells and Enhances the Efficacy of Adoptive T-Cell Transfer in Breast Cancer
Authors: Alizadeh Darya , Trad Malika , Hanke Neale T. , Larmonier Claire B. , Janikashvili Nona , Bonnotte Bernard , Katsanis Emmanuel , Larmonier Nicolas
Published: April 2023

PDF file - 93K
Supplementary Figure 5 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

PDF file - 53KB, SGK1 expression.
Supplementary Figure 4 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

PDF file - 111KB, SNAI2 protein in C4-2B/Rx2dox cells grown under serum free conditions.
Data Supplement from Microbiota Modulate Tumoral Immune Surveillance in Lung through a γδT17 Immune Cell-Dependent Mechanism
Authors: Cheng Min , Qian Liting , Shen Guodong , Bian Geng , Xu Tingjuan , Xu Weiping , Shen Gan , Hu Shilian
Published: April 2023

Supplemental Figure 1. Th17 cells are not induced in the lung after the tumor cell challenge. Supplemental Figure 2. No significant difference in the production of IFN-gamma by NK cells in the Abt mice compared with the control.
Supplementary Table S1 from FOXP3 Regulates Sensitivity of Cancer Cells to Irradiation by Transcriptional Repression of BRCA1
Authors: Li Weiquan , Katoh Hiroto , Wang Lizhong , Yu Xiaochun , Du Zhanwen , Yan Xiaoli , Zheng Pan , Liu Yang
Published: April 2023

Supplementary Table S1 XLS file - 40K, Foxp3 regulated genes as revealed by analysis of cDNA array data
Supplementary Figure 2 from Sunlight UV-Induced Skin Cancer Relies upon Activation of the p38α Signaling Pathway
Authors: Liu Kangdong , Yu Donghoon , Cho Yong-Yeon , Bode Ann M. , Ma Weiya , Yao Ke , Li Shengqing , Li Jixia , Bowden G. Tim , Dong Ziming , Dong Zigang
Published: April 2023

PDF file - 145K, The MAPK protein spectrum activated by UVA, UVB or SUV. (A) N/TERT-1 cells were irradiated with UVA (60 kJ/m2), UVB (3.6 kJ/m2) or SUV (60 kJ UVA/m2/3.6 kJ UVB/m2). Protein extracts (500 μg) were used for MAPK array analysis. Array spots were visualized using an ECL kit. The density of the each duplicated array spot in Fig. 2A was measured as described in Materials and Methods. The graph shows the fold change in SUV-induced phosphorylation of all 21 proteins compared to untreated control (i.e., value of 1). Data are shown as an average of duplicate samples. (B) Identification of proteins comprising the human phospho-MAPK array.
Supplementary Figure 1 from Sunlight UV-Induced Skin Cancer Relies upon Activation of the p38α Signaling Pathway
Authors: Liu Kangdong , Yu Donghoon , Cho Yong-Yeon , Bode Ann M. , Ma Weiya , Yao Ke , Li Shengqing , Li Jixia , Bowden G. Tim , Dong Ziming , Dong Zigang
Published: April 2023

PDF file - 45K, Identification of transgenic mice. The transgenic mice were identified by the tail test method. The tail (1 cm) was cut when the mouse was 12 d old. The genomic DNA was extracted using lysis buffer (100 mM Tris-HCl pH 8.5, 5 mM EDTA, 0.2% SDS, and 200 mM NaCl) with Proteinase K. K14 forward and reverse primers were used for PCR and ras was amplified as a control.
Supplementary Table S1 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Table S1 PDF file - 435K, ist of RT-PCR primers used for validation
Supplementary Figure S9 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S9 PDF file - 1478K, Expression levels of the LNX2 module
Supplementary Figure S8 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S8 PDF file - 391K, Reduction of CTNNB1 after siRNA against LNX2
Supplementary Figure S7 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S7 PDF file - 3031K, Molecular network analysis of downstream targets of KLF5 and LNX2
Supplementary Figure S6 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S6 PDF file - 2364K, Heatmap of the RNAi-signatures of the eight candidate genes
Supplementary Figure 4 from Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals
Authors: Miyabayashi Koji , Ijichi Hideaki , Mohri Dai , Tada Motohisa , Yamamoto Keisuke , Asaoka Yoshinari , Ikenoue Tsuneo , Tateishi Keisuke , Nakai Yousuke , Isayama Hiroyuki , Morishita Yasuyuki , Omata Masao , Moses Harold L. , Koike Kazuhiko
Published: April 2023

Supplementary Figure 4 PDF file - 177K, The effect of erlotinib was mainly through the inhibition of MAPK signaling
Supplementary Figure 2 from Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals
Authors: Miyabayashi Koji , Ijichi Hideaki , Mohri Dai , Tada Motohisa , Yamamoto Keisuke , Asaoka Yoshinari , Ikenoue Tsuneo , Tateishi Keisuke , Nakai Yousuke , Isayama Hiroyuki , Morishita Yasuyuki , Omata Masao , Moses Harold L. , Koike Kazuhiko
Published: April 2023

Supplementary Figure 2 PDF file - 97K, MEK inhibition reduced the gemcitabine-induced activation of EGFR and ErbB2 in the PDAC cells
Supplementary Figure S2 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S2 PDF file - 1800K, Corroboration of gene expression levels by qRT-PCR
Supplementary Figure 1 from Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals
Authors: Miyabayashi Koji , Ijichi Hideaki , Mohri Dai , Tada Motohisa , Yamamoto Keisuke , Asaoka Yoshinari , Ikenoue Tsuneo , Tateishi Keisuke , Nakai Yousuke , Isayama Hiroyuki , Morishita Yasuyuki , Omata Masao , Moses Harold L. , Koike Kazuhiko
Published: April 2023

Supplementary Figure 1 PDF file - 186K, Exogenous EGF rescued gemcitabine-induced apoptosis in vitro
Supplementary Figure S12 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S12 PDF file - 1822K, Model for LNX2 mechanism of action
Supplementary Table 2 from xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma
Authors: Yoshikawa Momoko , Tsuchihashi Kenji , Ishimoto Takatsugu , Yae Toshifumi , Motohara Takeshi , Sugihara Eiji , Onishi Nobuyuki , Masuko Takashi , Yoshizawa Kunio , Kawashiri Shuichi , Mukai Makio , Asoda Seiji , Kawana Hiromasa , Nakagawa Taneaki , Saya Hideyuki , Nagano Osamu
Published: April 2023

PDF file - 70K, Gene list and SAM P values of GSEA analysis in Figure S4.
Supplementary Figure S10 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S10 PDF file - 230K, Minimal region of amplification in 13q12.2
Supplementary Figure S1 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S1 PDF file - 1274K, Schematic presentation of the workflow of experiments and analytical procedures
Supplementary Methods from xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma
Authors: Yoshikawa Momoko , Tsuchihashi Kenji , Ishimoto Takatsugu , Yae Toshifumi , Motohara Takeshi , Sugihara Eiji , Onishi Nobuyuki , Masuko Takashi , Yoshizawa Kunio , Kawashiri Shuichi , Mukai Makio , Asoda Seiji , Kawana Hiromasa , Nakagawa Taneaki , Saya Hideyuki , Nagano Osamu
Published: April 2023

PDF file - 98K
Supplementary Figure Legend from xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma
Authors: Yoshikawa Momoko , Tsuchihashi Kenji , Ishimoto Takatsugu , Yae Toshifumi , Motohara Takeshi , Sugihara Eiji , Onishi Nobuyuki , Masuko Takashi , Yoshizawa Kunio , Kawashiri Shuichi , Mukai Makio , Asoda Seiji , Kawana Hiromasa , Nakagawa Taneaki , Saya Hideyuki , Nagano Osamu
Published: April 2023

PDF file - 81K
Supplementary Table 1 from Deficiency of Phospholipase A2 Group 7 Decreases Intestinal Polyposis and Colon Tumorigenesis in ApcMin/+ Mice
Authors: Xu Changxin , Reichert Ethan C. , Nakano Tomoyuki , Lohse Mariah , Gardner Alison A. , Revelo Mónica P. , Topham Matthew K. , Stafforini Diana M.
Published: April 2023

PDF file - 63K, Differential PLA2G7 expression in colorectal adenocarcinomas versus normal tissues, as determined by immunohistochemical analyses reported in the literature.
Supplementary Figure 4 from xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma
Authors: Yoshikawa Momoko , Tsuchihashi Kenji , Ishimoto Takatsugu , Yae Toshifumi , Motohara Takeshi , Sugihara Eiji , Onishi Nobuyuki , Masuko Takashi , Yoshizawa Kunio , Kawashiri Shuichi , Mukai Makio , Asoda Seiji , Kawana Hiromasa , Nakagawa Taneaki , Saya Hideyuki , Nagano Osamu
Published: April 2023

PDF file - 156K, GSEA of microarray data for OSC19/HSC-4 cell (GSE41495) and cetuximab-resistant/cetuximab-sensitive HNSCC (GSE21483) profiles.
Supplementary Figure 1 from xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma
Authors: Yoshikawa Momoko , Tsuchihashi Kenji , Ishimoto Takatsugu , Yae Toshifumi , Motohara Takeshi , Sugihara Eiji , Onishi Nobuyuki , Masuko Takashi , Yoshizawa Kunio , Kawashiri Shuichi , Mukai Makio , Asoda Seiji , Kawana Hiromasa , Nakagawa Taneaki , Saya Hideyuki , Nagano Osamu
Published: April 2023

PDF file - 521K, A and B. The relationship between CD44v expression and sulfasalazine sensitivity. C and D. The effect of CD44 RNAi on cell growth of HNSCC cells.
Supplementary Figure 1 from Deficiency of Phospholipase A2 Group 7 Decreases Intestinal Polyposis and Colon Tumorigenesis in ApcMin/+ Mice
Authors: Xu Changxin , Reichert Ethan C. , Nakano Tomoyuki , Lohse Mariah , Gardner Alison A. , Revelo Mónica P. , Topham Matthew K. , Stafforini Diana M.
Published: April 2023

PDF file - 60K, cPAF-induced de-phosphorylation of pAKT473 does not require Gαi/ Gαo or PKA
Supplementary Table 2 from The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models
Authors: Miyajima Naoto , Tsutsumi Shinji , Sourbier Carole , Beebe Kristin , Mollapour Mehdi , Rivas Candy , Yoshida Soichiro , Trepel Jane B. , Huang Ying , Tatokoro Manabu , Shinohara Nobuo , Nonomura Katsuya , Neckers Len
Published: April 2023

PDF file - 69K, Crizotinib and ganetespib synergistically reduce growth of wild-type and mutant MET-driven tumor xenografts.