bluuebunny/crossref_metadata_2025 huggingface dataset:
Insights Into Atopic Dermatitis – From Pathogenesis to Therapy
Authors: Papadakis K. , Handjieva-Darlenska T. , Tafradjiiska-Hadjiolova R. , Nocheva H.
Published: May 2023

Atopic dermatitis (AD), or eczema, is a common skin disease that is often associated with other atopic disorders, such as allergic rhinitis and asthma. The disease can develop both in infancy and adulthood, and characterizes with recurrent episodes impairing the quality of life. The review аnalyzes the genetical, immunological, and environmental factors in the pathogenesis of AD. The role of the skin barrier function is also considered in regard of the main hypotheses for AD development. Further elucidation of the mechanisms involved in the pathogenesis of AD could give interesting and useful clues for therapeutic protocols and prophylactic approaches.
Blood Transfusion in Covid-19 Patients: One Year Survey
Authors: Ali Sevigean , Badea Andreea Iulia , Lepadatu Olimpia , Petrovici Maria , Daba Lavinia , Botnarciuc Mihaela
Published: May 2023

Introduction: Due to the COVID-19 outbreak, many chronic patients and elective surgical procedures have been postponed to create spaces for the hospitalization of COVID-19 patients, raising issues related to this change. The objective of this study is to assess the effect of the COVID-19 pandemic on the demand for blood products transfusion.

Materials ant methods: The study presents the results of a retrospective study of blood transfusions in COVID-19 patients admitted to the Constanta County Emergency Clinical Hospital. The period of study was January-December 2021. We compared the transfusion requirement for each type of blood component in COVID 19 patients versus patients with non-COVID pathology.

Results and discussions: During 2021, we transfused 282 COVID-19 patients; 150 patients had only Covid pneumonia (of which 19 patients with severe forms needed intensive care in ICU-Covid), and 132 patients had various co-morbidities. The maximum blood requests was registered in the period February - April 2021, with a peak of 63 patients in April 2021. The main co-morbidities in patients with Covid 19 were: severe anemia in patients with malignant hemopathies. Anemia at admission in patients with Covid pneumonia is reported in more than 40% of patients . Moderate anemia (Hb <11 g/dL) is considered as an independent risk factor for the severe course of COVID-19 infection and mortality in these patients. The transfusion requirement in these patients was greater than 1.43 RBC (units/patient), 0.81 Plasma units/patient, 0.40 Platelets concentrate units + single donor platelet concentrate units/patient, in accordance with the associated pathology.

Conclusions: The most requested product was packed red blood cells, the correction of anaemia being an important factor in preventing the severe course of the disease. The platelet requirement was 0.15 units/patient, thrombocytopenia being present in patients with severe evolution of the infection (hospitalized in ICU-COVID). The most requested blood groups were O+ and A+. COVID-19 transfusion data will help plan and prepare for the use of blood resources during the pandemic.
Applicability of Induction Furnace Steel Slag in RC Columns Subjected to Axial and Uniaxial Loading
Authors: Ali Zahraa H. , Khalid Nibras N.
Published: May 2023

Carbon emissions and sand mining have generated massive environmental imbalances. Because of the impact of depleting resources, using slag in concrete is a viable alternative for minimizing environmental impact. The acceptability of using induction furnace steel slag as a partial replacement for aggregate and as an additive in concrete mixtures for columns was investigated. Ten 140 mm × 140 mm × 750 mm short columns subjected to axial and uniaxial loads were tested. The outcome demonstrates that using SS in general decreases displacement levels and increases load levels. The proposed steel slag as a 30 % sand replacement mixture is preferred over the others. All the suggested combinations showed decreases in the ductility ratio and energy absorption. Induction furnace steel slag can be used in concrete columns.
Permanent Deformation Evaluation of Modified Asphaltic Pavement Based on Numerical Simulation Models
Authors: Alhelyani Akram , Zhang Shuwen
Published: May 2023

Since the use of additives supplies the different properties required to develop better-performing roadways, modification with additives has been used as one of the attractive alternatives when the base asphalt does not satisfy the requirements for traffic load, climate variations, and paving structure. This study evaluates the effect of additive materials of improving the ability of the surface layer to withstand permanent deformation. In addition, it discusses to what extent using waste materials as additive materials affects permanent deformation resistance and the extent of using waste materials as alternative modifiers to commercial polymers to enhance permanent deformation resistance. In this study, the simulation using the ABAQUS program under the conditions of using different percentages of the additives, changes in the thickness of the surface layer, and increasing the temperature on permanent deformation of the asphalt layer was investigated. The simulation results showed that using modified mixtures improved the Hot Mix Asphalt HMA's properties and decreased the mixtures' temperature susceptibility, which manifested as a decrease in permanent deformation (lower rutting depth) when compared to an unmodified mixture. Furthermore, using waste materials led to the greatest decrease in permanent deformation among all models.
Shear and Flexural Behavior of Lightweight Concrete Beams Containing Hybrid Fibers
Authors: Al-Khafaji Noora H. A. , Harba Ibrahim S. I.
Published: May 2023

Due to the low density of lightweight concrete, work has been done in this research to develop it by adding fibers of more than one type to improve its properties. Basic tests were conducted to determine the properties of concrete before and after the addition of fibers. The variables of the models were beams in two groups (shear and flexural). The variables of these two groups included the type of fibers (steel and polypropylene) and the size of the added fibers 0 %, 0.05 %, 0.1 % for polypropylene fibers 0 %, 0.75 %, 1 % for steel fibers. This study presented an examination of 18 beam specimens and discussed the results, which included mechanical properties (air dry density, slump test, compressive strength, modulus of elasticity, flexural strength, and splitting tensile strength). The results showed that the addition of fibers had an effective effect on the compressive strength, and this led to an increase in the resistance to shear forces and flexural forces, as the highest load capacity was shown by adding polypropylene fibers at a rate of 0.1 % in both groups, and the fibers played an important role in reducing the width of cracks and controlling their spread due to modulus of elasticity of the fiber.
Incremental Dynamic Analysis and Seismic Fragility Analysis of Reinforced Concrete Frame
Authors: Awchat Ganesh , Patil Abhishek , More Ashish , Dhanjode Gopal
Published: May 2023

Due to technological developments in last decade, new methods of seismic evaluation are in use like simulation based, algorithm based, probabilistic, software based etc. These developments have enabled researchers to move from linear to non-linear methods of analysis. Incremental dynamic analysis (IDA) is performance evaluation method where a suite of ground motions applied to structure are further scaled to particular levels of seismic intensity. Seismic fragility curves become significant in estimation of structures risk possibility from the point of view of potential earthquakes and helps in predicting the economic consequences for forthcoming earthquakes. The paper reflects IDA and seismic fragility analysis of ground storey + 7 floor (G + 7) reinforced concrete frame subjected to suite of eleven ground motions. Primary objective was to perform equivalent static and linear-dynamic analysis to meet the National and International codal requirements. Then, pushover analysis is carried out by introducing parametric auto hinges as per ASCE 41-13 tables. To carry out pushover analysis, both geometric and material non-linearity was introduced. Strong ground motions were selected as per suitable criteria of seismic intensity. IDA is then carried out as per SeismoStruct 2022 software and using IDA curves, the fragility analysis was carried out. The results of study found useful for researchers to predict the probability of damage of the structure under earthquakes.
Cam teach and prosper? EFL teachers’ attitudes, well-being, and coping strategies in an online setting
Authors: Martinović Anna , Dumančić Dino
Published: May 2023

The global Covid-19 pandemic led to the turn toward online learning and the need to adapt to new ways of English foreign language (EFL) teaching. This mixed-methods research aimed to examine teacher attitudes, well-being, and coping strategies related to online EFL teaching. The results indicated that Croatian EFL teachers had a positive attitude toward online teaching and acknowledged the importance of being digitally competent. EFL teachers were unsure about their ability to deal with online teaching and indicated their need to improve their IT skills. They revealed more negative than positive responses regarding their well-being and showed that they tried to actively cope during the pandemic. Results also showed better coping strategies among female teachers.
Challenges of distance English teaching: Narrative analysis of Iranian mainstream EFL teachers’ lived experiences
Authors: Fakharzadeh Mehrnoosh , Naderi Mohammad Hassan
Published: May 2023

This study aimed to examine what challenges Iranian EFL teachers in the mainstream educational system experienced in distance classes during the COVID-19 pandemic. Telephone unstructured narrative interview was employed to collect data from 20 teacher participants, and two theoretical frameworks, CoI and TPACK, were used to interpret the results. The thematic narrative analysis yielded ten themes: non-customized platforms, material-related issues, connection/internet issues, pedagogical problems, evaluation problems, insufficiency of teachers’ knowledge of technology, unmet expectations, physical absence of teacher/student, student-related issues, and dealing with negative emotions. The authors discuss that while some challenges are the antecedent contextual challenges that existed and will probably continue to exist in the context of distance classes, some other challenges can be avoided if teachers are equipped with TPACK to fulfill their new roles in the community of distance classes.
Exclamatives as means of exhibiting emotions in Henry James’s Washington Square: Pragmatic aspect
Authors: Lapka Olha
Published: May 2023

The article aims to analyse exclamatives as means of expressing emotions in dialogical discourse through the Speech Acts Theory. In particular, it dwells upon the representation of the Universal Emotion by the sub-classes of speech acts on the material of Henry James’s Washington Square. For this purpose, a structural-semantic analysis, a speech acts analysis, an intentional analysis, and a statistical analysis were used in the research. The results established pragmatic regularities of using the exclamatives in the course of communication in the novel. Thus, emotions play an essential role in constructing the character’s individual features, each of them having his/her predominant emotion. In addition, the statistical analysis showed that the majority of the analysed exclamatives are used to express the emotions of anger, joy, and sadness, which are construed predominantly by expressive and representative speech acts.
Simulation of Pipe Networks Using EPANET to Optimize Water Supply: A Case Study for Arjawinangun Area, Indonesia
Authors: Safitri Adam , Wahyudi Slamet Imam , Soedarsono
Published: May 2023

In providing clean water services to a community, a clean water supply distribution network system is very important. This study is aimed at the determination of the distribution pipe network by simulating and optimizing the water supply system in the Arjawinangun area, Cirebon, West Java, Indonesia. The data collected was analyzed by using EPANET 2.0 software for modelling water distribution systems. The results show that the total domestic and non-domestic water demand is 391.41 l/s, with a leakage rate of 20%. The pipeline installation plan for the Arjawinangun area is planned to be installed for a length of 23,045 m, with pipe diameters ranging from 400 to 90 mm. The Arjawinangun Area O take Reservoir drainage system, which is at an elevation of +25 m above sea level, requires a distribution pump with a head (H) of 6.0 bar. Also, using the gravity distribution technique, a water tower can be built (~ 55 m) as a water supply booster pump.
Seismic analysis of Fractured Koyna Concrete Gravity Dam
Authors: Ouzandja Djamel , Messaad Mokhtar , Berrabah Amina T. , Belharizi Mohamed
Published: May 2023

Seismic analysis of a fractured dam is a generally complex problem. This paper presents an earthquake behavior investigation of a fractured concrete gravity dam considering dam-reservoir--foundation rock interaction. The Koyna dam profile, located in India, is adopted in this study. The nonlinear finite element analyses are conducted taking into account empty and full reservoir cases, to exhibit the hydrodynamic e ect of reservoir water on the dam earthquake response. The hydrodynamic pressure is modeled by fluid finite elements based on a Lagrangian approach. Transient analyses take into account material and connection nonlinearity. Drucker-Prager model is employed in nonlinear analyses for the dam concrete and foundation rock. The structural crack between the top and bottom blocks of the dam is presented by surface-to-surface contact elements based on Coulomb’s friction law in order to simulate the behavior of contact joints and deformation of blocks. The distribution of horizontal displacements and principal stresses along the dam height is investigated for empty and full reservoir cases.The failure processes of two potential failure modes of cracked dam, i.e, the separation and sliding of top block during an earthquake, are examined.
The Work of Reproduction in the Age of Digital Art: The Role of ‘Aura’ in the Revitalisation of Vinyl Records and Cassettes
Authors: Tsitsos William E. , Saylor Breckenridge R.
Published: May 2023

We explain recent popularity in vinyl records by reframing Walter Benjamin’s notion of ‘aura’ in terms of social forces such as alienation and cultural capital. Where he pays attention to specific artefacts’ mechanical reproducibility as a way of assessing their aura, we consider how mediums themselves broadly possess variable levels of aura inversely related to their ability to be mechanically reproduced by consumers. The more easily consumers can reproduce a medium, the less aura it possesses.
Influence of Fibers on Fresh and Mechanical Properties of (FRC) Fiber Reinforced Concrete, A Step Towards Sustainability
Authors: Ahsan M. , Adil Sultan M. , Ahmad Z. , Cheema S. , Jawad M. , Kanwal Humaira , Asim M. , Mughal Tayyaba Latif , Tahir M. , Mahmood Amna , Mughal Sadia
Published: May 2023

Mostly used material is concrete which has versatile quality for construction works. Fibrous concrete have significant factor that improve the scale and value to concrete for humid environments with significant role. Day by day abundant demand and use of concrete is increasing. It is considered as a 2nd largest building material due to the major productivity. By the use of fibrous concrete, some bonding and environmental issues have been addressed. Keeping in this view, an experimental based study is conducted to evaluate the strength of fiber reinforced concrete at different percentages 0%, 0.5%, 1.0%, 1.5% and 2.0%. All percentages are added by the weight of concrete with all fibers. In this connection, one hundred and fifty-three cylinders of five mixes are prepared. Workability checked of fresh concrete during the pouring of concrete cylinders. Poured cylinders’ samples are left for different curing ages at 7 and 28 days. One hundred and two cylinders for compression at 7 and 28days but fifty-one cylinders for split tensile test at 28days with all fibers i.e. glass fiber, steel fiber, coconut fiber and polypropylene fiber. After curing, compression and split tensile tests are performed to check the strength of hardened concrete. Workability of five mixes lies between 40-90mm.Fibrous concrete is suitable for humid environment where high strength and voids less concrete are required. Addition of fibers in concrete may improves the strength parameters as well as to increase the bonding and tensile properties of concrete. It reduces the quantity of water to be used in concrete. Also the use of different types of fibers has been proved to be economical and is considered as environmental friendly construction material.
The Effect of Brick and Glass Powder on the Mechanical Properties and Porosity of Self-Compacting Mortar
Authors: Bouleghebar Yasmina , Bentchikou M. , Boukendakdji O. , El-Hadj K. , Debieb F. , Maisarah Ali
Published: May 2023

The use of glass and brick powder waste as supplementary cementious material provides an effective approach to produce concrete in order to effectively save resources and solve environmental pollution problems. This study shows the evolution of the preparation of an eco-friendly self-compacting mortar (SCM) with various fineness levels and replacement ratios of crushed glass and crushed calcined brick waste. Cement was replaced by weight, by 8, 12, 16, 20, 24% of glass powder (GP) and 4, 8, 12, 16 and 20% of crushed brick powder (BP), with three specific surface Blaine (SSB) fineness measurements (F1=3300cm2/g,F2=4400 cm2/g and F3=6000 cm2/g) for both wastes. Mini-slump and V-funnel flow time tests of fresh SCM were evaluated. Compressive and flexural strength developments of cured SCMs were determined on 7, 14, 28, 5 6, and 90 days. In addition, porosity of SCM was also evaluated. The results revealed that the (SCM-GP) mix increases workability and reduces superplasticizer dosage, while the (SCMBP) mix reduces workability with a slight increase in superplasticizer. When the GP fineness is higher than the cement fineness, the compression strength with GP contents up to 16% is superior to without the GP, whereas for the BP the strength improvement is up to 8%, while the compression strength decreases when the GP and BP fineness is close or lower than the cement fineness. The porosity diminishes with the increase of the fineness; the 12% of the GPF3 indicated the lowest porousness at 400 days, whereas for SCM-BP the 8BPF3 is the least porous mixture.
The different effects of regional and local winds on dew formation in the Negev desert
Authors: Kidron Giora J. , Kronenfeld Rafael , Temina Marina
Published: May 2023

With dew serving as an important water source for various small organisms and plants in deserts, knowledge regarding the spatial distribution of dew (which constitutes an important fraction of the non-rainfall water, NRW) is of prime importance. This is also the case for the Negev dew desert. According to the classical model, local nocturnal katabatic winds that descend down the slopes during the night to the wadi beds are responsible for the accumulation of cold air, subsequently triggering dew formation in the wadis. Nevertheless, NRW measurements that were conducted in a one-order drainage basin in the Negev during the dewy season (late summer and fall) yielded half the amount in the wadi bed in comparison to the hilltop, attributed to the sheltered position of the wadi from the cooling effect of the regional (sea-breeze) winds, which are not considered by the classical model. Hypothesizing that the classical model may however take place at wide wadi where the sea breeze winds are not sheltered, measurements of dew and temperatures were periodically carried out at the beds of a 5 m-wide narrow (NW) and a 200 m-wide (WW) wadi beds and at the hilltop (HT). The findings did not fully support our hypothesis. In comparison to the hilltop, and despite the mutual effect of the katabatic and the sea breeze winds on the wide wadi bed, also the wide wadi exhibited lower amounts of dew than that of the hilltop, with NRW following the pattern HT > WW > NW. The overwhelming effect of the sea-breeze winds was also supported indirectly by periodic NRW and temperature measurements during the winter during which the sea breeze does not commonly take place. Evidence suggests that whereas the classical model takes place during the winter during which the katabatic winds may play a central role in dew formation, the occurrence of the sea breeze (regional wind) during the late summer and fall overshadows the effect of the local katabatic winds. Our findings point to the possibility that the classical model may not adequately predict dew formation in regions subjected to sea-breeze winds.
Sustainable Consumer Activities of Varna Households
Authors: Kehayova-Stoycheva Maria , Ivanov Svilen , Vasilev Julian
Published: May 2023

The purpose of this article is to present the process for developing individual indexes of sustainable household actions in several thematic areas of sustainable consumption. These areas are energy efficiency, electricity and water consumption, food consumption, transport use and product disposal. Based on these individual indexes, a proposal for the creation of an aggregated individual household index for sustainable consumption is discussed. Based on the developed indexes, a segmentation of households into three basic segments is proposed. The proposed indexes are designed based on the results of a survey conducted among 342 households from the city of Varna, Bulgaria in the months of January - April 2022. The proposed indexes, after adaptation, can be used as a tool for self-assessment of sustainable household consumption in different cities and countries. In this sense, as a result of their implementation, it is expected that the motivation of households towards inclusion in sustainable consumption will be increased.
The Potential of Work From Home for Determining Job Quality
Authors: Porancea-Răulea Andreea Simina
Published: May 2023

Job quality is carefully studied in the research literature and there are multiple models for analyzing relevant indicators. The COVID-19 pandemic has impacted employees’ work and lives, leading to changes in work patterns. Much of the discussions fell under the label of the possibility of working from different places and the implications of information technology on the perceived quality of a workplace. The present study examines the relationship between the perceived quality in the context of distance working. To address the current situation the study emphasizes how the theory, research, and practice have evolved in regard to perceived work quality and its implication for employees. The notion of perceived organization quality was broadened, and the implication of working from home was analyzed from the employees’ point of view. How the possibility of working from home affects the perceived quality of an organization and how this will shape the organization’s functions are subjects of this article. The findings contribute to the understanding of employees’ behavior with choosing a workplace and the key factors that shape the image of a quality organization.
The Mediating Effect of Profitability on the Relationship Between Working Capital Management and Sustainable Growth
Authors: Suntraruk Phassawan
Published: May 2023

This study investigates the relationship between working capital management and sustainable growth, taking into account the mediating role of profitability. The study uses a sample of non-financial companies that were listed on the Thai Stock Exchange between 2010 and 2020. This study documents the absence of direct relationship between working capital management and sustainable growth using fixed effects regression models. Nonetheless, it is found that profitability appears to be a mediating factor in this relationship. Companies can attempt to minimize their cash conversion cycle to enhance their profitability, which will further help them raise their sustainable growth. Furthermore, companies with higher operating cash flows and those with lower financial debt are able to achieve higher profitability and sustainable growth. Remarkably, this study shows that large companies are more profitable and have higher sustainable growth than smaller ones.
High-tech radiation methods in the diagnosis of endometrial cancer – multiparametric MRI, ultrasound tomography, 3D angiography, energy dopplerography
Authors: Nudnov N. V. , Ivashina S. V. , Aksenova S. P.
Published: May 2023

The increase in the incidence of endometrial cancer is noted not only in postmenopausal women, but also in a socially active group of women of reproductive age, starting from 25 years. Ultrasound and magnetic resonance imaging (MRI) are the main methods of non-invasive diagnosis of endometrial cancer. Our study included 69 patients with endometrial cancer stages I–IV aged 30 to 79 years. The diagnostic informativeness of the MRI method in detecting tumor invasion into the myometrium for all groups was: sensitivity – 82.30%, specificity – 6.6%, PPV – 93.30%, NPV – 40%. The diagnostic informativeness of the ultrasound method in detecting tumor invasion into the myometrium for all groups was: sensitivity – 91.3%, specificity – 88.4%. The peculiarity of this study was to evaluate the possibilities of radiation methods (ultrasound, MRI) in the staging of endometrial cancer.
18FDG PET-CT significance for post-treatment monitoring in cervical and uterine cancer patients with suspected recurrence in previously irradiated zones
Authors: Solodkiy V. A. , Nudnov N. V. , Kreynina Yu. M. , Shevchenko L. N. , Kaskulova M. Kh. , Titova V. A. , Pronkina E. V. , Vorobjeva V. O.
Published: May 2023

Early detection of cervical (CC) and endometrial (EC) cancer recurrence in previously irradiated areas remains a difficult task for clinicians and radiologists. 18F-FDG PET-CT scope and limits in this matter are not clear yet.

Purpose. To determine 18F-FDG PET-CT significance and diagnostic value in differential diagnosis of locoregional recurrence and post-radiation tissue changes in CC and EC patients with suspected relapse in preirradiated zones.

Materials and methods. Follow-up data, including multiparametric MRI (T1-WI, T2-WI, DWI, DCE) and 18FFDG PET-CT full descriptions, were studied in 51pts., in 25(49%) CC and 26 (51%) EC Ia–IIIc FIGO, with suspected loco-regional recurrence in pre-irradiated area, 4–96 months after the end of treatment.

Adjuvant combined radiotherapy (conformal pelvic EBRT – 3D-CRT, IMRT, VMAT, endovaginal 192Ir HDR brachytherapy) was performed in 33 (64,7%) pts. after radical surgery, adjuvant chemoradiation with Cisplatin 40 mg/m2 or Carboplatin AUC2 weekly – in 8 (24.2%) of them. 18 (35,3%) pts. were treated with definitive chemoradiation, median EQD2 for HR-CTV D90 81.6 ± 4.4 Gy (CI 95% 72.4 Gy – 93.7 Gy) and 54.6 ± 3.3 Gy (CI 95% 48.8–64.2 Gy) for metastatic pelvic and paraaortic lymph nodes.

Indications for 18F-FDG PET-CT (Biograph True64, Siemens, 3.8–4.7 MBq/kg, total 169–356 MBq) in all pts. were suspicious clinical, cytological, complex ultrasound, and multiparametric MRI findings in pre-irradiated zones. Any areas of 18F-FDG pathologically increased uptake were considered hypermetabolic lesions, positive for cancer recurrence.

Results. No evidence of loco-regional recurrence in pre-irradiated zones was confirmed in 32 (62.7%) pts. Clinical, morphological and radiological signs of progression were obtained in 16 (31.3%) 18F-FDG PET-CTpositive patients, with SUVmax 2.86–8.8 in this subgroup. 18F-FDG PET-CT false-positive results were obtained in 6 (11.8%) patients, false-negative – in 1 (1.9%) heavy pre-treated CC patient. 18F-FDG PET-CT sensitivity was 94.1%, specificity – 84.2%, positive predictive value – 72.7%, negative predictive value – 96.9%.

Conclusions. 18F-FDG-PET-CT has a high diagnostic value in the differential diagnosis of loco-regional relapses and post-radiation tissue changes in CC and EC patients with suspected progression in pre-irradiated zones. But 18F-FDG-PET-CT findings evaluation and interpretation requires a multidisciplinary discussion and consensus for this cohort of patients.
Possibilities of CT angiography of the inferior mesenteric artery in planning resections of the left half of the colon in patients with colorectal cancer
Authors: Arablinskii A. V. , Seurko K. I. , Pashkovskaia A. A. , Voynovskiy A. E. , Stepanchenko A. P. , Kosenkov A. N.
Published: May 2023

During laparoscopic surgery for colorectal cancer, vascular structures may be incorrectly identified and damaged due to ignorance of the variant anatomy of the inferior mesenteric artery (IMA), lack of tactile sensations, narrowed field of vision, which leads to complications such as massive bleeding and intestinal ischemia. Therefore, the preoperative study of the variant anatomy of the IMA is of paramount importance. Knowing the variant anatomy of the vessels before surgery, you can make an operation plan in advance, which will ensure fast and safe vascular ligation at the required level and lymph dissection.

Aim: To develop a classification of IMA variability for practical use in operations for colorectal cancer. Optimize the standard abdominal scanning protocol to improve the accuracy of MSCT and the best visualization of the IMA and its branches.

Material and methods. From February 2013 to March 2022, 214 computed tomograms (CT) of abdominal organs with intravenous contrast were analyzed. We studied the variant anatomy of the IMA. The abdominal cavity scanning protocol was optimized using a 100 kV tube voltage, the contrast density of the NBA and its branches was compared using standard and optimized scanning protocols during a retrospective analysis of 105 CT studies of abdominal organs.

Results. We proposed the classification of structure of the IMA and its branches. This is especially important when the safe lymph node dissection along the IMA is necessary. I type – several colonic branches derivate from the IMA by independent trunks (54%); II type – all colon branches derivate from the IMA in one point like a “goose paw” (25%); III type – one colon branch departs from the IMA by a single trunk; then it divides into colonic branches (21%).

The accuracy of MSCT of the abdominal organs with intravenous contrast, which was determined by comparing the results of studies with intraoperative data, was 97.9%. The sensitivity of the method is 95.8%, the specificity of the method is 100%.

The use of a scanning protocol with a tube voltage of 100 kV makes it possible to simplify and speed up the determination of the anatomical type of structure, improve the visualization of the IMA and its branches.

Conclusion. CT with 3D-reconstruction of vessels allows the surgeon to perform an extended LND for colorectal cancer with a minimal risk of complications.
Using an artificial intelligence algorithm to assess the bone mineral density of the vertebral bodies based on computed tomography data
Authors: Artyukova Z. R. , Kudryavtsev N. D. , Petraikin A. V. , Abuladze L. R. , Smorchkova A. K. , Akhmad E. S. , Semenov D. S. , Belyaev M. G. , Belaya Zh. E. , Vladzimirskyy A. V. , Vasiliev Yu. A.
Published: May 2023

Goal: To develop a method for automated assessment of the volumetric bone mineral density (BMD) of the vertebral bodies using an artificial intelligence (AI) algorithm and a phantom modeling method.

Materials and Methods: Evaluation of the effectiveness of the AI algorithm designed to assess BMD of the vertebral bodies based on chest CT data. The test data set contains 100 patients aged over 50 y.o.; the ratio between the subjects with/without compression fractures (Сfr) is 48/52. The X-ray density (XRD) of vertebral bodies at T11-L3 was measured by experts and the AI algorithm for 83 patients (205 vertebrae). We used a recently developed QCT PK (Quantitative Computed Tomography Phantom Kalium) method to convert XRD into BMD followed by building calibration lines for seven 64-slice CT scanners. Images were taken from 1853 patients and then processed by the AI algorithm after the calibration. The male to female ratio was 718/1135.

Results: The experts and the AI algorithm reached a strong agreement when comparing the measurements of the XRD. The coefficient of determination was R2=0.945 for individual vertebrae (T11-L3) and 0.943 for patients (p=0.000). Once the subjects from the test sample had been separated into groups with/without Сfr, the XRD data yielded similar ROC AUC values for both the experts – 0.880, and the AI algorithm – 0.875. When calibrating CT scanners using a phantom containing BMD samples made of potassium hydrogen phosphate, the following averaged dependence formula BMD =0.77*HU-1.343 was obtained. Taking into account the American College Radiology criteria for osteoporosis, the cut-off value of BMD<80 mg/ml was 105.6HU; for osteopenia BMD<120 mg/ml was 157.6HU. During the opportunistic assessment of BMD in patients aged above 50 years using the AI algorithm, osteoporosis was detected in 31.72% of female and 18.66% of male subjects.

Conclusions: This paper demonstrates good comparability for the measurements of the vertebral bodies’ XRD performed by the AI morphometric algorithm and the experts. We presented a method and demonstrated great effectiveness of opportunistic assessment of vertebral bodies’ BMD based on computed tomography data using the AI algorithm and the phantom modeling.
CT-sign “ground glass opacity” in granulomatosis with polyangiitis and community-acquired pneumonia
Authors: Safonova1 T. D. , Sheikh Zh. V.
Published: May 2023

Granulomatosis with polyangiitis (GPA) is a rare systemic disease characterized by two parallel processes: necrotizing granulomatous inflammation and low-immune vasculitis predominantly affecting small vessels. Differential diagnosis of lung lesions on CT in patients with an established diagnosis of granulomatosis with polyangiitis can be very difficult.

Purpose. Developing computed tomography criteria for the differential diagnosis of infiltrative changes in the lungs in patients with GPA and community-acquired bacterial pneumonia.

Materials and methods. 67 CT examinations of the chest by 24 patients with verified GPA with infiltrative lung lesions and 36 CT examinations by 30 patients with bacterial pneumonia without concomitant pulmonary pathology, a comparative analysis of the following characteristics of ground glass opacity symptom was performed: “location", “craniocaudal distribution”, “uniformity”, “localization”, “quantity”, “association with consolidation”, “association with pleural effusion”. CT was performed natively on a Toshiba Aquilion Prime CT scanner according to a standard examination protocol with a slice thickness of 1 mm. Statistical processing of the obtained results was carried out

using the software application RStudio, version 1.3.1093 for mac OS (RStudio, PBC). To study the relationships between two categorical variables, the χ2 independence test and the principal component method for categorical

variables were used.

Results. GPA is characterized by multiple bilateral areas of ground glass opacity compaction, often with a central location, without a statistically significant craniocaudal dependence in the lung regions. In community-acquired pneumonia, this sign is more likely to be unilateral with a peripheral location in the lower lobes of the lung. Statistically significant differences in the degree of homogeneity, combination with consolidation, pleural effusion have not been established.

Conclusion. CT reveals the characteristic features of the ground glass opacity CT sign in GPA and pneumonia, which, together with clinical and laboratory data, increase the accuracy of radiodiagnosis of these diseases.
Presentación
Authors: Prieto Stambaugh Antonio
Published: May 2023

Este año 2023 celebramos tres décadas de la fundación de la Asociación Mexicana de Investigación Teatral (AMIT) que desde sus inicios estableció el proyecto de crear un anuario en el que se publicarían trabajos derivados de sus congresos. Así surgió la revista Investigación Teatral, con Domingo Adame y Octavio Rivera como editores del número inaugural publicado en mayo de 1995 (aunque en la portada se consigna el año 1993, cuando se celebró el primer congreso de la AMIT). El Consejo Editorial incluye a figuras internacionales de la talla de Erika Fischer-Lichte, Josette Féral, Nel Diago y Eli Rozik.
Un gótico entre nosotros: Martín Zapata
Authors: Vincent Nidia
Published: May 2023

Se presenta una aproximación a la producción y poética no realista del dramaturgo mexicano Martín Zapata (1963). El artículo se centra en la obra que va de 1979 a 2016, correspondiente a sus dos primeras épocas (iniciación y exploración), bajo dos constantes: lo especular (metadrama) y la estética fantástico-gótica.
Martín Zapata: A Gothic Playwright Among Us
Abstract
This article discusses the poetic and non-realistic dramatic production of Mexican playwright Martín Zapata (1963). It focuses on the study of plays written from 1979 to 2016, which belong to his first two periods (initiation and exploration). Zapata’s work is analyzed under two aspects: as specular metadrama, and the fantastic-gothic aesthetic.
Recibido: 8 de diciembre de 2022Aceptado: 16 de febrero de 2023
Artes escénicas en espacios de privación de la libertad. Una mirada transdisciplinaria
Authors: García Carrión Thania Mariela
Published: May 2023

El presente testimonio describe la experiencia práctica que realicé al llevar herramientas de las artes escénicas al reclusorio de Pacho Viejo, Veracruz, durante los años 2017-2019. En este texto presento los desafíos de llevar a cabo un taller con 20 internos para lograr un acercamiento sensible y humano con personas recluidas en una prisión. Expongo las posibilidades que tienen las artes escénicas para generar vínculos y fortalecer el tejido social desde una cultura de paz a través de las artes. El sustento de mi trabajo en el reclusorio fue el paradigma transdisciplinario, mismo que permite transitar por distintos niveles de realidad desde la complejidad de lo escénico.
The Performing Arts in Prisons. A Transdisciplinary Perspective
Abstract
The following is a testimony of a performing arts project I implemented in the prison of Pacho Viejo, Veracruz, during 2016-2019. I describe the challenges of organizing a workshop for 20 inmates, with the aim of achieving a humane and sensible approach with people whose liberty is restricted. I discuss the potential that performing arts have in forging alliances and restoring the social fabric within a culture of peace. The project was based on the transdisciplinary paradigm, which allows for navigating different levels of reality withing the complex practice of performing arts.
Recibido: 28 de febrero de 2023
Aceptado: 06 de marzo de 2023
Chona. A self-made woman: disidencia en la re-existencia buchona
Authors: Chávez Sánchez Silverio
Published: May 2023

Por medio de un espectáculo con estructura de cabaret político mexicano, el grupo Gueza Cabaret nos cuenta la vida de Chona, personaje ficticio originario de la ciudad de Coatzacoalcos, Veracruz, que busca desesperadamente salir de la pobreza. La historia es contada por su amiga, compañera y cómplice de toda la vida, La Lupe, quien nos narra entre bailes, bromas y risas los altibajos de la trayectoria de Chona en su ascenso social. Mas allá de la risa y de la diversión que transmite el personaje, Chona es un ejemplo de la forma en la cual las mujeres nombradas como buchonas construyen sus vidas.
Recibido: 10 de febrero 2023
Aceptado: 13 de febrero 2023
José Ramón Alcántara Mejía (1945-2023) y Georges Banu (1943-2023) Fidelidad al teatro y a la amistad
Authors: Adame Domingo
Published: May 2023

¿Qué es lo que hay en el espacio que se abre cuando alguien experimenta el dolor por la muerte de un ser querido, y el momento en que el sujeto experimentador muere? Me interesa esta pregunta no por querer saber lo que sentirán mis seres queridos cuando muera, sino porque me parece que, por más que sea un proceso natural y continuo, contiene un potencial de sentido, el cual permite valorar con profundidad lo inexorable de nuestro destino
Epidemiological and clinical analysis of infection with the new coronavirus in the pediatric population: a systematic review
Authors: Santa Larissa , Prado Mateus , Vedovatto Mônica , Almeida Jáder
Published: May 2023

OBJECTIVE: The main objective of this study is to collection review the literature in order to analyze epidemiologically and clinically the infection by the new Coronavirus in the pediatric public. METHODS: To carry out such an analysis , articles were selected through a structured search strategy in the databases of Pubmed , Cochrane and Scielo. The articles were selected according to to the recommendations of the preferred reporting Items for Systematic Reviews and Meta- analysis Protocol (PRISMA-P). and the review protocol (Prospero) was registered at York University under the following identification number : CRD CRD42020197304. RESULTS: The literature search identified 985 articles. After methodological screening , 6 studies were eligible for this systematic review. The number of participants ranged from 10 to 43 children aged between 1 month and 16 years old with a predominance of the male population. The clinical presentation was variable , and it can show from asymptomatic forms , which represent the vast majority , to severe cases that result in death. In symptomatic cases, the disease usually manifests itself through mild symptoms of the respiratory tract. In more severe cases, patients may have respiratory failure and multisystemic inflammatory syndrome. CONCLUSIONS: Studies have shown that children have milder clinical presentations when compared to adults , in addition to faster recovery and better prognosis. The cause for the difference in the manifestation of the disease is not completely elucidated with several hypotheses being studied. In terms of treatment , the care offered is only supportive , aiming at patient comfort and management of comorbidities.
Pancreatitis subsequent to SARS-CoV-2 infection in a pediatric indigenous patient from the Paranapua tribe
Authors: Sá Kamilla , Cruz Gabriela , Flores Isabella , Araújo Lorena , Estebez Emília , Holanda Iane , Silva Gabriela , Martins Ulisses , Martins Marilene , Dedivits Rogério
Published: May 2023

OBJECTIVE: To hypothesize a correlation between previous infection by SARS-Cov-2 and acute pancreatitis due to the inflammatory process caused by the virus in an indigenous pediatric patient. CASE REPORT: A 7-year-old female indigenous patient, from the Paranapua tribe, with a history of contact with community with COVID-19 infected, presenting with acute pancreatitis of unknown etiology even after laboratory and imaging investigation, presenting with pulmonary involvement and IgG positive for SARS-CoV-2. COMMENTS: At the threshold of the COVID-19 pandemic, there was an increase in the involvement of various organs and systems, especially in pediatric patients, intriguing the appearance of inflammatory conditions such as acute pancreatitis. This case report describes a rare extrapulmonary form of COVID-19, not yet described in the literature, and a possible correlation between viral inflammation and pancreatic involvement in an indigenous patient from Paranapua.
Pencarian Inhibitor DYRK2 dari Database Bahan Alam Zinc15: Analisis Farmakofor, Simulasi Docking dan Dinamika Molekuler
Authors: Aman La Ode , Sihaloho Mangara , Arfan Arfan
Published: May 2023

DYRK2 (Dual-specificity tyrosine phosphorylation-regulated kinase 2) merupakan protein kinase yang memiliki banyak peranan dalam berbagai proses biologis, termasuk pembelahan sel, proliferasi sel, diferensiasi sel, dan apoptosis. DYRK2 diantaranya terlibat dalam regulasi siklus sel dengan cara mengatur aktivitas proteasom 26S sehingga inhibisi aktivitas DYRK2 dapat menghambat fungsi proteasom 26S dan mengurangi proliferasi sel kanker. Secara in vitro, kurkumin menunjukan kemampuan mengurangi proliferasi sel kanker melalui penghambatan enzim DYRK2. Pada penelitian ini, analog kurkumin telah diskrining dari database bahan alam Zinc15 dengan menggunakan model farmakofor yang diperoleg dengan pendekatan berbasis ligan. Hasil skrining kemudian dievaluasi dengan menerapkan teknik docking molekuler dan dinamika molekuler berdasarkan energi interaksi, rata-rata energi pengikatan bebas dan stabilitas interaksi antara ligan dan situs aktif DYRK2. Skrining terhadap 270.547 molekul dari database bahan alam Zinc15 menghasilkan 110 senyawa hit terpilih. Dengan mempertimbangkan hasil simulasi docking dan dinamika molekuler, tiga analog kurkumin prospektif telah dipilih yaitu ZINC000085597244, ZINC000217945958, dan ZINC000217643970. Molekul-molekul ini memiliki kriteria yang lebih baik dibandingkan kurkumin pada beberapa kriteria, seperti energi interaksi, energi pengikatan bebas, dan stabilitas interaksi dengan target. Disimpulkan, senyawa-senyawa ZINC000085597244, ZINC000217945958, dan ZINC000217643970 diprediksi sebagai kandidat potensial untuk obat anti-kanker dengan mekanisme aksi spesifik terhadap DYRK2.
El consumo responsable como un desafío social
Authors: Mejia-Giraldo Juan F. , Arango-Román Alexander
Published: May 2023

El objetivo del artículo es analizar el consumo responsable como un desafío social al cual se ven enfrentados individuos de la ciudad de Medellín, Colombia, con el fin de comprender, desde sus vivencias y a su escala, el trabajo de las estructuras en el diseño de esta prueba colectiva. Para esto, se realizaron 26 entrevistas (tomando como referencia la sociología de los desafíos sociales) a consumidores con alto grado de identificación con las marcas de vestuario Nike, Adidas y H&M, las cuales han sido objeto de cuestionamientos por sus prácticas productivas. Entre los hallazgos, se observa que los actores aprecian la contradicción planteada en un contexto social que los incita a comprar constantemente y que, al mismo tiempo, los sitúa como los grandes responsables por los impactos negativos, reconociendo que las estructuras sociales parecen conspirar en favor de un consumo que no se articula a uno con rasgos de responsabilidad.
Reseña sobre el libro “Intimidad burocrática. Precarización laboral, clientelismo y sentido del trabajo en el Estado colombiano”
Authors: Ladino-Orjuela Wilson H.
Published: May 2023

Martínez, S. P. y García, F. A. (2021). Intimidad burocrática. Precarización laboral, clientelismo y sentido del trabajo en el Estado colombiano. Universidad del Valle.