bluuebunny/crossref_metadata_2025 huggingface dataset:
Observation of the Apoapsis of S62 in 2019 with NIRC2 and SINFONI
Authors: Peißker Florian , Eckart Andreas , Ali Basel
Published: September 2021

Given the increased attention toward the detection of faint stars in the Galactic center, we would like to address the detectability of S62 in its apoapsis with the Spectrograph for INtegral Field Observations in the Near Infrared at the Very Large Telescope (SINFONI; VLT) and the Near-Infrared Camera 2 (NIRC2; KECK) in this work. Because of the nearby stars and the chance of confusion, we are using Lucy–Richardson deconvolved images to detect S62 on its Keplerian orbit around Sgr A* with a period of less than 10 yr. We use the same data set as for S62 to trace additionally the S-cluster star S29 at the expected position based on the orbital elements presented in this work. To verify the results of the filtering technique, we are analyzing K-band continuum data of the same epoch independently observed with NIRC2/KECK. Based on the well-derived orbit of S62, we find the star in projection at the expected position in 2019.4 and 2019.5. By analyzing the SINFONI data of 2019.5, we confirm the 16.1 ± 0.2 mag for S62 that was formerly derived with NAOS-CONICA (NACO; VLT). We base our NACO imaging analysis on the robust data set that was previously used to investigate the Schwarzschild precision of S2. We also present a critical discussion of the elsewhere proposed linear trajectory of S62 and its disputed identification with a 19 mag star found with GRAVITY mounted at the VLT Interferometer.
Antenatal Care for Pregnant Women Infected with HIV/AIDS in Bonto Bahari District, Bulukumba Regency, Indonesia
Authors: Raodhah Sitti , Syahrir Sukfitrianty , Nildawati Nildawati , Nuryana Andi , Lagu Abd. Majid H.R.
Published: September 2021

Objectives: The purpose of this study was to determine the description of Antenatal Care in pregnant women infected with HIV/AIDS in Bonto Bahari District, Bulukumba Regency. Methods: This study used a qualitative method with a phenomenological approach. Data were collected through in-depth interviews with snowballing sampling techniques. The number of informants was six people consisting of one key informant and five primary informants. Results: The knowledge of pregnant women about HIV was low. In areas where HIV-infected pregnant women live, the health service centre is available such as a Public Health Centre (Puskesmas) that can be accessible. Pregnant women were looking for treatment at the Puskesmas around their area. Unfortunately, some pregnant women did not search for any treatment since they were afraid of their HIV status revealed by Health workers and people in Puskesmas. At Puskesmas, they only obtained poor service and discriminated from other non-HIV pregnant women. Those pregnant women acquired support from the family emotionally, financially, and information support. However, some of them also had no support from their families after knowing their illness. Conclusion: Knowledge of HIV/AIDS by pregnant women with HIV positive was low. After realising that their husbands were infected, they were furious and disappointed with their husbands. Besides, the health workers were not good at serving those pregnant women positively with HIV/AIDS. They tended to discriminate from other patients without HIV/AIDS. Family support for pregnant women was including emotional, financial, and information supports
Spatial Pattern Analysis of Malaria Cases in Muara Enim Regency using Moran Index and Local Indicator Spatial Autocorrelation
Authors: Sunarsih Elvi , Zulkarnain Muhammad , Hanum Laila , Flora Rostika , Damiri Nurhayati
Published: September 2021

BACKGROUND: Malaria is a disease which still becomes a global health issue, including in Indonesia, because of its potential vector which can infect and spread causing a wide impact. Until currently, malaria still becomes a serious threat to people living in tropical and subtropical areas. Muara Enim Regency is a malaria-endemic regency with the second highest positive case in South Sumatra Province, with an API value in 2019 was 0.18/1000 population.

AIM: The current research was performed to identify and change the spatial pattern of malaria cases, environmental variability (rainfall), population density using Moran index and local indicator spatial autocorrelation (LISA), and habitat in Muara Enim Regency.

METHODS: This research employed a quantitative research design with an analytical survey research method and a case–control approach. This research method was designed using a geographic information systems approach.

RESULTS: The results of the study showed that malaria cases in Muara Enim Regency in 2017 occurred in groups with a Moran index of 0.263, indicating a positive autocorrelation. Meanwhile, based on the LISA index, it was found that there were three districts categorized as high-high (HH) (quadrant 1), those are Lawang Kidul District, Muara Enim District, and Gunung Megang District, while in the low-high (LH) category (quadrant 2), there was Benakat District. In 2018, it also occurred in groups where the Moran index was 0.129, indicating a positive autocorrelation, while the LISA index found that there was one district categorized as HH (quadrant 1) which is Lawang Kidul District, and district categorized as LH (quadrant 2) was Gunung Megang District. In 2019, it happened randomly or spread with a Moran index of −0.022 indicating a negative autocorrelation, while based on the LISA index, it was found that there was one subdistrict categorized as HH category (quadrant 1) which is Lawang Kidul District and two districts categorized as LH (quadrant 2) which are Semende Darat Laut and Rambang Niru.

CONCLUSION: There was a change in the results of Moran index from a positive autocorrelation in 2017, 2018, to a negative autocorrelation in 2019 with the results of the LISA index for malaria cases in 2017–2019 in one subdistrict, namely, Lawang Kidul District categorized as a HH category (quadrant 1).
Relationship of Patellofemoral Osteoarthritis to Changes in Performance-based Physical Function Over 7 Years: The Multicenter Osteoarthritis Study
Authors: Hart Harvi F. , Neogi Tuhina , LaValley Michael , White Daniel , Zhang Yuqing , Nevitt Michael C. , Torner James , Lewis Cora E. , Stefanik Joshua J.
Published: September 2021

Objective

To determine the relationship of patellofemoral osteoarthritis (PFOA) to changes in performance-based function over 7 years.

Methods

There were 2666 participants (62.2 ± 8.0 yrs, BMI 30.6 ± 5.9 kg/m2, 60% female) from the Multicenter Osteoarthritis Study with knee radiographs at baseline who completed repeated chair stands and a 20-meter walk test (20MWT) at baseline, 2.5, 5, and 7 years. Generalized linear models assessed the relation of radiographic PFOA and radiographic PFOA with frequent knee pain to longitudinal changes in performance-based function. Analyses were adjusted for age, sex, BMI, tibiofemoral OA, and injury/surgery.

Results

Linear models demonstrated a significant group-by-time interaction for the repeated chair stands (P= 0.04) and the 20MWT (P< 0.0001). Those with radiographic PFOA took 1.01 seconds longer on the repeated chair stands (P= 0.02) and 1.69 seconds longer on the 20MWT (P< 0.0001) at 7 years compared with baseline. When examining the relation of radiographic PFOA with frequent knee pain to performance-based function, there was a significant group-by-time interaction for repeated chair stands (P= 0.05) and the 20MWT (P< 0.0001). Those with radiographic PFOA with frequent knee pain increased their time on the repeated chair stands by 1.12 seconds (P= 0.04) and on the 20MWT by 1.91 seconds (P< 0.0001) over 7 years.

Conclusion

Individuals with radiographic PFOA and those with radiographic PFOA with frequent knee pain have worsening of performance-based function over time. This knowledge may present opportunities to plan for early treatment strategies for PFOA to limit functional decline over time.
Soins palliatifs : proposition ou imposition
Authors: Fulchiron Héléna , Burelli Christine
Published: September 2021

Chaque pratique a son socle de construction truffé d’idéaux. S’ils donnent, dans un premier temps, une orientation bienveillante, ils peuvent devenir néfastes. C’est aussi le cas parfois des soins palliatifs dont la pratique est sous tendue par un « vouloir le bien pour l’autre » tout autant que par un idéal de ce que serait « la bonne mort ». Cet article se propose alors de questionner ces postures afin de réinterroger le positionnement que chacun peut prendre face à un sujet singulier.
Quelle élaboration possible d’une approche palliative en maternité ?
Authors: Béchu Alice
Published: September 2021

Associer soins palliatifs et maternité constitue un paradoxe qui provoque une effraction : cela bouleverse l’ordre générationnel pensé dans notre société. Cet article explore l’expérience d’une psychologue de soins palliatifs qui intervient en maternité autour de la perte périnatale. Prise dans une ambivalence entre angoisse et élaboration, un psychologue extérieur convoqué pour traiter la question de la mort au début de la vie permet un travail singulier, clinique et institutionnel, sur cette dimension douloureuse à l’hôpital.
Traumatisme, non-deuil et pulsion de mort. Quelles transmissions aux générations futures ?
Authors: Lassagne Boris
Published: September 2021

Les expériences traumatiques et la confrontation avec la mort gardent toute leur intensité lorsqu’elles ne sont pas reliées à un maillage signifiant permettant le travail psychique de la perte de l’objet d’amour. Toutes les pertes étant à la fois objectales et narcissiques, refoulées ou déniées, ces blessures restées vivaces auront diverses incidences sur les modes d’être des sujets concernés. L’objet de cet article est de mettre en perspective les perturbations liées au traumatisme de la perte d’un enfant. Les conséquences de ces pertes seront évaluées sur la dynamique familiale ainsi que sur les structures psychiques des descendants et plus particulièrement sur celle d’un homme de 35 ans.
Rationalité de l’État et causes de la guerre
Authors: Baranets Élie
Published: September 2021

La guerre génère des coûts si élevés que l’on peine à identifier quelle fin ce moyen pourrait rationnellement servir. Pour le déterminer, nous présentons les analyses qui, en Relations internationales, voient dans l’État un acteur unitaire. C’est le cas des théories qui, situées au niveau du système international, étudient la manière dont la puissance est distribuée entre les différents États. C’est aussi le cas des théories qui, situées au niveau des interactions entre États, étudient leurs interactions. Ces deux approches permettent de comprendre, respectivement, l’émergence d’un climat d’hostilité entre certaines entités politiques, et les modalités de la compétition militaire qu’il génère.
Les causes du conflit ethnique : un état des lieux
Authors: Panel Sophie
Published: September 2021

Les guerres civiles constituent aujourd’hui la forme la plus fréquente et la plus meurtrière de conflit armé. La majorité de ces conflits sont « ethniques » dans le sens où ils opposent des belligérants issus de groupes ethniques distincts. Cet article passe en revue la littérature sur les causes des conflits ethniques : il fournit un aperçu sur les mesures quantitatives communément employées, présente quelques faits centraux sur la distribution de ces conflits, puis discute six théories du conflit ethnique en les confrontant de façon systématique aux résultats de la recherche empirique. Il ressort de cette synthèse que les conflits ethniques sont rares en termes absolus (si on les rapporte au nombre de groupes ethniques qui cohabitent dans chaque État) mais fréquents en termes relatifs (si on les compare aux guerres civiles non ethniques), et qu’ils s’expliquent davantage par des facteurs d’ordre économique que par la persistance d’antagonismes historiques ou des divergences culturelles.
La guerre est-elle dans notre nature ?
Authors: Gat Azar , Baranets Élie
Published: September 2021

La possibilité de la guerre comme celle de la paix sont présentes au fond de chacun d’entre nous. La boîte à outils des comportements humains comprend un certain nombre d’outils majeurs, destinés respectivement au conflit violent, à la compétition pacifique, ou à la coopération, en fonction de l’évaluation faite par chacun de ce qui leur sera le plus utile dans des circonstances données. Le conflit n’est qu’un de ces outils – le marteau – parmi un éventail d’outils comportementaux diversifiés. Ces trois stratégies comportementales ne sont pas toutes purement acquises par la culture. La dichotomie naïve inné/acquis ignore la machine biologique lourde et complexe à l’origine de chacune de ces stratégies comportementales et de leurs interactions réciproques. Parce qu’ils ont tous été fort pratiques tout au long de notre évolution, ces outils nous apparaissent à la fois comme étant à notre portée et prêts à être activés. Dans le même temps, ils sont étalonnés de manière variable en fonction des conditions particulières à travers l’apprentissage culturel, indiquant que leur utilité relative est susceptible de grandement fluctuer. Ainsi, l’émergence d’une autorité étatique coercitive a orienté le menu des stratégies comportementales vers des options pacifiques sur la scène interne ; l’évolution des conditions économiques, sociales et politiques pourrait conduire à un effet similaire à l’échelle internationale.
Facteurs thérapeutiques et anti-thérapeutiques de l’analyste, selon Herbert Rosenfeld
Authors: Ithier Béatrice
Published: September 2021

L’auteure souhaite exposer la méthodologie d’Herbert Rosenfeld présente dans Impasse et interprétation, en l’articulant à certaines notions de Klein et de Bion. Elle considère que la préoccupation méthodologique de Rosenfeld marquée par la considération du trauma constitue la dominante de son dernier parcours. Le modèle du transfert psychotique ne se réduit ni à la schizophrénie, ni aux états confusionnels et narcissiques négatifs, mais va se trouver étendu aux états borderline et à tout processus analytique. L’auteure souligne dans cette approche une réflexion sur l’interprétation du transfert et du contre-transfert, adossée aux différentes modalités de l’identification projective et de la notion contenant-contenu de Bion. La prise en compte de l’impact de l’état d’esprit de l’analyste sur le patient, de même que le traitement de l’émotionnel entre eux, renvoie au cœur de l’analyse contemporaine.
Nexus between crude oil prices, clean energy investments, technology companies and energy democracy
Authors: Özdurak Caner ,   Financial Economics Department, Yeditepe University, İstanbul, Turkey
Published: September 2021

In this study, we examine the nexus between crude oil prices, clean energy investments, technology companies, and energy democracy. Our dataset incorporates four variables which are S & P Global Clean Energy Index (SPClean), Brent crude oil futures (Brent), CBOE Volatility Index (VIX), and NASDAQ 100 Technology Sector (DXNT) daily prices between 2009 and 2021. The novelty of our study is that we included technology development and market fear as important factors and assess their impact on clean energy investments. DCC-GARCH models are utilized to analyze the spillover impact of market fear, oil prices, and technology company stock returns to clean energy investments. According to our findings when oil prices decrease, the volatility index usually responds by increasing which means that the market is afraid of oil price surges. Renewable investments also tend to decrease in that period following the oil price trend. Moreover, a positive relationship between technology stocks and renewable energy stock returns also exists.
A novel dynamic brain network in arousal for brain states and emotion analysis
Authors: Gao Yunyuan ,   College of Automation, Hangzhou Dianzi University, Hangzhou, China, Cao Zhen , Liu Jia , Zhang Jianhai ,   Key Laboratory of Brain Machine Collaborative Intelligence of Zhejiang Province, Hangzhou, China,   Department of Industrial and Systems Engineering, Auburn University, Auburn, AL, United States,   School of Computer Science and Technology, Hangzhou Dianzi University, Hangzhou, China
Published: September 2021

Background

Brain network can be well used in emotion analysis to analyze the brain state of subjects. A novel dynamic brain network in arousal is proposed to analyze brain states and emotion with Electroencephalography (EEG) signals.

New Method

Time factors is integrated to construct a dynamic brain network under high and low arousal conditions. The transfer entropy is adopted in the dynamic brain network. In order to ensure the authenticity of dynamics and connections, surrogate data are used for testing and analysis. Channel norm information features are proposed to optimize the data and evaluate the level of activity of the brain.

Results

The frontal lobe, temporal lobe, and parietal lobe provide the most information about emotion arousal. The corresponding stimulation state is not maintained at all times. The number of active brain networks under high arousal conditions is generally higher than those under low arousal conditions. More consecutive networks show high activity under high arousal conditions among these active brain networks. The results of the significance analysis of the features indicates that there is a significant difference between high and low arousal.

Comparison with Existing Method(s)

Compared with traditional methods, the method proposed in this paper can analyze the changes of subjects' brain state over time in more detail. The proposed features can be used to quantify the brain network for accurate analysis.

Conclusions

The proposed dynamic brain network bridges the research gaps in lacking time resolution and arousal conditions in emotion analysis. We can clearly get the dynamic changes of the overall and local details of the brain under high and low arousal conditions. Furthermore, the active segments and brain regions of the subjects were quantified and evaluated by channel norm information.This method can be used to realize the feature extraction and dynamic analysis of the arousal dimension of emotional EEG, further explore the emotional dimension model, and also play an auxiliary role in emotional analysis.
Thematic Analysis of Nurses’ Experiences With The Joint Commission’s Medication Management Titration Standards
Authors: Davidson Judy E. , Chechel Laura , Chavez Jose , Olff Carol , Rincon Teresa
Published: September 2021

Background

For decades, medication titration has been within nurses’ scope and practice. In 2017 The Joint Commission (TJC) revised elements for orders for the titration of continuous intravenous medications.

Objectives

To explore the practice and perceptions of nurses regarding TJC standards for titration of continuous intravenous medications.

Methods

Nurses with experience titrating medications completed an investigator-designed, validated cross-sectional survey. Inductive thematic analysis was conducted in order to analyze the open-ended comments from that quantitative survey.

Results

From among 730 completed surveys, 159 comments were received. Analysis of the comments yielded 3 levels of abstraction. Two overarching themes were harm and professionalism. Additional abstraction for the harm theme revealed categories of erosion of workplace wellness, moral dilemma, and patient safety, which were coded as relating to workplace stress, workload, burnout/turnover, physical risk, inefficiency, demeaning/devalued, falsification of records, problematic orders, burden of documentation, suboptimal care, delay in care, individualized care, and provider availability. Within the professionalism theme, categories of autonomy and nurse proficiency were identified, with 7 associated codes: top of scope, critical thinking, overregulation, teamwork, education, registered nurse knowledge, and novice registered nurse guidance.

Conclusions

The standards from TJC impose harm by eroding workplace wellness and introducing moral dilemmas and patient safety concerns. Professionalism is threatened through limits on scope and autonomy. Further advocacy is necessary in order to resolve unanticipated consequences related to the titration standards.
Long-Term Evolution of the Adaptive NKG2C+ NK Cell Response to Cytomegalovirus Infection in Kidney Transplantation: An Insight on the Diversity of Host–Pathogen Interaction
Authors: Ataya Michelle , Redondo-Pachón Dolores , Llinàs-Mallol Laura , Yélamos José , Alari-Pahissa Elisenda , Pérez-Sáez María J , Altadill Mireia , Raïch-Regué Dàlia , Vilches Carlos , Pascual Julio , Crespo Marta , López-Botet Miguel
Published: September 2021

Human CMV infection is frequent in kidney transplant recipients (KTR). Pretransplant Ag-specific T cells and adaptive NKG2C+ NK cells associate with reduced incidence of infection in CMV+ KTR. Expansions of adaptive NKG2C+ NK cells were reported in posttransplant CMV-infected KTR. To further explore this issue, NKG2C+ NK, CD8+, and TcRγδ T cells were analyzed pretransplant and at different time points posttransplant for ≥24 mo in a cohort of CMV+ KTR (n = 112), stratified according to CMV viremia detection. In cryopreserved samples from a subgroup (n = 49), adaptive NKG2C+ NK cell markers and T cell subsets were compared after a longer follow-up (median, 56 mo), assessing the frequencies of CMV-specific T cells and viremia at the last time point. Increased proportions of NKG2C+ NK, CD8+, and TcRγδ T cells were detected along posttransplant evolution in viremia(+) KTR. However, the individual magnitude and kinetics of the NKG2C+ NK response was variable and only exceptionally detected among viremia(–) KTR, presumably reflecting subclinical viral replication events. NKG2C+ expansions were independent of KLRC2 zygosity and associated with higher viral loads at diagnosis; no relation with other clinical parameters was perceived. Increased proportions of adaptive NKG2C+ NK cells (CD57+, ILT2+, FcεRIγ–) were observed after resolution of viremia long-term posttransplant, coinciding with increased CD8+ and Vδ2– γδ T cells; at that stage CMV-specific T cells were comparable to viremia(–) cases. These data suggest that adaptive NKG2C+ NK cells participate with T cells to restore CMV replication control, although their relative contribution cannot be discerned.
Anti-Monomeric C-Reactive Protein Antibody Ameliorates Arthritis and Nephritis in Mice
Authors: Fujita Chitose , Sakurai Yasuo , Yasuda Yuki , Takada Yoshikazu , Huang Cheng-Long , Fujita Masaaki
Published: September 2021

Conformation-specific Ags are ideal targets for mAb-based immunotherapy. Here, we demonstrate that the monomeric form of C-reactive protein (mCRP) is a specific therapeutic target for arthritis and nephritis in a murine model. Screening of >1800 anti-mCRP mAb clones identified 3C as a clone recognizing the monomeric, but not polymeric, form of CRP. The anti-mCRP mAb suppressed leukocyte infiltration in thioglycollate-induced peritonitis, attenuated rheumatoid arthritis symptoms in collagen Ab-induced arthritis model mice, and attenuated lupus nephritis symptoms in MRL/Mp-lpr/lpr lupus-prone model mice. These data suggest that the anti-mCRP mAb 3C has therapeutic potential against rheumatoid arthritis and lupus nephritis.
USP21 Deubiquitinase Regulates AIM2 Inflammasome Activation
Authors: Hong Yujin , Lee Seong-Ok , Oh Changhoon , Kang Kwonyoon , Ryoo Jeongmin , Kim Dongyoung , Ahn Kwangseog
Published: September 2021

Innate immune sensing of cytosolic DNA via absent in melanoma 2 (AIM2) is a key mechanism leading to inflammatory responses. As aberrant immune responses by dysregulated AIM2 are associated with autoinflammatory diseases, activation of the AIM2 inflammasome should be tightly controlled. In this study, we discovered that ubiquitination and deubiquitination of AIM2 are critical events that regulate AIM2 inflammasome activation. In resting human macrophage cells, AIM2 is constitutively ubiquitinated and undergoes proteasomal degradation to avoid autoinflammation. Upon DNA stimulation, USP21 binds to AIM2 and deubiquitinates it, thereby increasing its protein stability. In addition to the role of USP21 in regulating AIM2 turnover, we uncovered that USP21-mediated deubiquitination of AIM2 is required for the assembly of the AIM2 inflammasome. Depletion of USP21 does not affect the DNA-binding ability of AIM2 but inhibits the formation of the AIM2–ASC complex. Our findings establish that fine-tuning of AIM2 by the ubiquitin system is important for regulating AIM2 inflammasome activation.
Association between Metabolic Syndrome and Microvascular Complications in Chinese Adults with Type 1 Diabetes Mellitus
Authors: Huang Qianwen , Yang Daizhi , Deng Hongrong , Liang Hua , Zheng Xueying , Yan Jinhua , Xu Wen , Liu Xiangwen , Yao Bin , Luo Sihui , Weng Jianping
Published: September 2021

Background: Both type 1 diabetes mellitus (T1DM) and metabolic syndrome (MetS) are associated with an elevated risk of morbidity and mortality yet with increasing heterogeneity. This study primarily aimed to evaluate the prevalence of MetS among adult patients with T1DM in China and investigate its associated risk factors, and relationship with microvascular complications.Methods: We included adult patients who had been enrolled in the Guangdong T1DM Translational Medicine Study conducted from June 2010 to June 2015. MetS was defined according to the updated National Cholesterol Education Program criterion. Logistic regression models were used to estimate the odds ratio (OR) for the association between MetS and the risk of diabetic kidney disease (DKD) and diabetic retinopathy (DR).Results: Among the 569 eligible patients enrolled, the prevalence of MetS was 15.1%. While female gender, longer diabetes duration, higher body mass index, and glycosylated hemoglobin A1c (HbA1c) were risk factors associated with MetS (OR, 2.86, 1.04, 1.14, and 1.23, respectively), received nutrition therapy education was a protective factor (OR, 0.46). After adjustment for gender, age, diabetes duration, HbA1c, socioeconomic and lifestyle variables, MetS status was associated with an increased risk of DKD and DR (OR, 2.14 and 3.72, respectively; both P<0.05).Conclusion: Although the prevalence of MetS in adult patients with T1DM in China was relatively low, patients with MetS were more likely to have DKD and DR. A comprehensive management including lifestyle modification might reduce their risk of microvascular complications in adults with T1DM.
Large-scale testing on compressibility characteristics of stiff backfill
Authors: Arjang B
Published: September 2021

The compressibility characteristics of various stiff fills on large-scale laboratory specimens were investigated to determine the effectiveness of additives on stiffness of rockfills. Combinations of cemented and uncemented rockfills with selected ranges of
tailings were tested under controlled loading conditions. Under a constant compression rate to a maximum load of 9 MN, load-deformation responses were obtained from test specimens confined in a rigid 0.50 m diameter cylinder. Compressibility data, stress-strain relationships and the function of void
ratio and material characteristics on stiffness of rockfills were evaluated. The results showed that at high stress levels strength and deformation characteristics of rockfills are primarily controlled by initial void ratio rather than by cement content. Based on laboratory evidence a fill type with
rockfill-tailings ratio of 5:1 has been identified which is expected to provide the desired ultimate stiffness under confined conditions in mining applications. However, additional testing is needed to develop an optimum fill utilizing uncemented rockfills.
Using flashcards for English second language creative writing in Grade 1
Authors: Mathura Shivona , Zulu Free-Queen B.
Published: September 2021

Background: English Second Language (ESL) learners have difficulty constructing sentences due to internalising information in their home language and thereafter translating it into English. Learners who have difficulty speaking English generally encounter problems writing it, which hampers their creative writing ability.Objectives: The purpose of the research was to identify a teaching strategy to facilitate ESL learners with creative writing. This study explored the influence of flashcards on the creative writing skills of Grade 1 ESL learners and improved the researchers’ teaching practice.Method: This qualitative study depicted an action research design and utilised an inductive approach to data analysis. Convenience sampling was used when selecting the participants who were 31 Grade 1 learners in a school in Pietermaritzburg. The flashcards were used during the implementation stage of the action research process as an intervention to enhance learners’ creative writing skills.Findings: The findings indicate that learners who participated in the study had improved in their written assessments. There were three themes identified, which included misspelt words, incorrect use of tenses and ungrammatical sentence construction. Flashcards revealed the correct sentence writing techniques by depicting sentences. Learners’ written pieces were more logical and they participated actively during lessons. This enhanced the researcher’s teaching practice, which catered to both visual and auditory learners.Conclusion: The findings suggest that the use of flashcards had a positive effect on ESL learners’ creative writing skills. This encouraged participatory teaching and learning, which can be of benefit to many teachers seeking to engage learners using alternate learning styles.
Prognostic significance of viable tumor size measurement in hepatocellular carcinomas after preoperative locoregional treatment
Authors: Hwang Yoon Jung , Lee Youngeun , Park Hyunjin , Lee Yangkyu , Lee Kyoungbun , Kim Haeryoung
Published: September 2021

Background: Preoperative locoregional treatment (LRT) for hepatocellular carcinoma (HCC) often induces intratumoral necrosis without affecting the overall tumor size, and residual viable tumor size (VTS) on imaging is an important clinical parameter for assessing post-treatment response. However, for surgical specimens, it is unclear whether the VTS would be more relevant to prognosis compared to total tumor size (TTS).Methods: A total of 142 surgically resected solitary HCC cases were retrospectively reviewed. The TTS and VTS were assessed by applying the modified Response Evaluation Criteria in Solid Tumors method to the resected specimens, and correlated with the clinicopathological features and survival.Results: As applying VTS, 13/142 cases (9.2%) were down-staged to ypT1a. Although the survival analysis results for overall survival according to TTS or VTS were similar, VTS was superior to predict disease-free survival (DFS; p = .023) compared to TTS (p = .08). In addition, multivariate analysis demonstrated VTS > 2 cm to be an independent predictive factor for decreased DFS (p = .001). In the subpopulation of patients with LRT (n = 54), DFS in HCCs with TTS or VTS > 2 cm were significantly shorter than those with TTS or VTS ≤ 2 cm (p = .047 and p = .001, respectively). Interestingly, HCCs with TTS > 2 cm but down-staged to VTS ≤ 2 cm after preoperative LRT had similar survival to those with TTS ≤ 2 cm.Conclusions: Although the prognostic impact of tumor size was similar regardless of whether TTS or VTS was applied, reporting VTS may help to increase the number of candidates for surgery in HCC patients with preoperative LRT.
A categorical characterization of quantum projective spaces
Authors: Mori Izuru , Ueyama Kenta
Published: September 2021

Let

R

be a finite dimensional algebra of finite global dimension over a field

k

. In this paper, we will characterize a

k

-linear abelian category

\mathscr C

such that

\mathscr C\cong \operatorname {tails} A

for some graded right coherent AS-regular algebra

A

over

R

. As an application, we will prove that if

\mathscr C

is a smooth quadric surface in a quantum

\mathbb P^3

in the sense of Smith and Van den Bergh, then there exists a right noetherian AS-regular algebra

A

over

kK_2

of dimension 3 and of Gorenstein parameter 2 such that

\mathscr C\cong \operatorname {tails} A

where

kK_2

is the path algebra of the 2-Kronecker quiver

K_2

.
Quasi-homogeneity of potentials
Authors: Hua Zheng , Zhou Guisong
Published: September 2021

In noncommutative differential calculus, Jacobi algebra (or potential algebra) plays the role of Milnor algebra in the commutative case. The study of Jacobi algebras is of broad interest to researchers in cluster algebra, representation theory and singularity theory. In this article, we study the quasi-homogeneity of a potential in a complete free algebra over an algebraic closed field of characteristic zero. We prove that a potential with finite dimensional Jacobi algebra is right equivalent to a weighted homogeneous potential if and only if the corresponding class in the 0th Hochschlid homology group of the Jacobi algebra is zero. This result can be viewed as a noncommutative version of the famous theorem of Kyoji Saito on isolated hypersurface singularities.
Association between Preferred Language and Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children in the United States
Authors: Otto William R. , Grundmeier Robert W. , Montoya-Williams Diana , Njoroge Wanjikũ F. M. , Wallis Kate E. , Gerber Jeffrey S. , Yun Katherine
Published: September 2021

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has had a disproportionate impact on Black, Hispanic, and other individuals of color, although data on the effect of a person’s language on SARS-CoV-2 infection are limited. Considering the barriers suffered by immigrants and non-English-speaking families, we tested whether children with a preferred language other than English was associated with SARS-CoV-2 infection. Children from families with a preferred language other than English had a higher predicted probability of SARS-CoV-2 test positivity (adjusted odds ratio, 3.76; 95% CI, 2.07–6.67) during the first wave of the pandemic. This discrepancy continued into the second wave (adjusted odds ratio, 1.64; 95% CI, 1.10–2.41), although the difference compared with families who prefer to speak English decreased over time. These findings suggest that children from non-English-speaking families are at increased risk of SARS-CoV-2 infection, and efforts to reverse systemic inequities causing this increased risk are needed.
Active Masking of Tonal Noise using Motor-Based Acoustic Generator to Improve EV Sound Quality
Authors: He Song , Miller John , Peddi Vinod , Omell Bill , Gandham Michael
Published: September 2021

Electric motor whine is one of the main noise sources of electric vehicles (EVs). Without engine masking noise, high pitch tonal noise from electric motor can be highly annoying and raise sound quality issues for electrified propulsion systems. This paper describes a patented new technology that controls electric motor to actively mask annoying high-pitch tonal noise by (i) controlling electric motor to create complementary low order tones to enrich sound complexity and distract high pitch tones; (ii) controlling motor to generate random dithering noise to raise masking noise floor and reduce tone-to-noise ratio around tonal targets; (iii) combining complementary injection at low frequency and dithering at high frequency for enhanced masking. This new technology enables controlling masking noise level, frequency, order and bandwidth as a function of motor torque and speed for most effective masking. The new active masking technology is successfully implemented and validated using GM’s Bolt EV in motor dyno and vehicle cabin noise tests. Jury tests are performed that confirm enhanced EV sound quality with slight impact on motor torque and efficiency.
Electrocardiographic alterations by pneumothorax: a case-control study with review of the literature
Authors: Minotti Bruno , Brenner Roman , May Desbiolles Lotus , Osterwalder Joseph , Schoch Otto D. , Ammann Peter
Published: September 2021

BACKGROUND: Numerous ECG alterations due to pneumothorax have been reported. The objective of the study was to establish the presence of ECG changes associated with pneumothorax in the literature, and in a cohort of patients with proven pneumothorax compared with age- and sex-matched healthy controls.
METHODS: A systematic review for ECG alterations associated with pneumothorax was performed. We then reviewed our hospital database for patients with pneumothorax and identified all patients with an ECG available at this time. The retrieved ECG alterations in the systematic review were identified in our pneumothorax patients and compared with a healthy sex- and age-matched control group. Accordingly, we calculated sensitivity and specificity for all alterations.
RESULTS: Seventeen ECG alterations were found and defined from the systematic review. Our pneumothorax cohort consisted of 82 pneumothorax patients and 82 control patients. Specificity was mostly more than 90%, but sensitivities were low. Phasic R voltage (pneumothorax group 25.6% vs control group 1.2%), T-wave inversion (31.7% vs 2.4%), prolonged QTc (11.0% vs 2.4%), right axis deviation (14.6% vs 3.6%) and QRS voltage ratio in aVF/I >2 (41.5% vs 22.0%) were significantly more frequent in pneumothorax patients compared with controls.
CONCLUSION: The sensitivity of published ECG signs in predicting pneumothorax in our cohort was low, which means that ECG findings are an unsuitable tool for pneumothorax screening. However, presence of these ECG signs might raise a suspicion of pneumothorax in patients presenting with dyspnoea, or unclear chest discomfort.
The Effect of Valproic Acid on the Transcriptional Activity of Ngf and Bdnf Genes of in Vitro Cultured Neurons Under Oxidative Stress Conditions
Authors: Filev A. D. , Ershova E. S. , Savinova E.A. , Кalakov A. M. , Veiko N. N. , Umriukhin P.E. , Kostyuk S.V.
Published: September 2021

Brain-derived neurotrophic factor (BDNF) is a secretory molecule that promotes peripheral neurons synaptic transmission and plasticity by TrkB receptor activation. This is shown in cultured central nervous system (CNS) neurons, including hippocampal and cortical cholinergic, dopaminergic and serotonergic neurons. Hypotheses suggesting that BDNF may play a potential role in the pathophysiology of schizophrenia are based on the key role of BDNF in the synaptic plasticity and, consequently, regulation of cognitive functions. In the schizophrenia treatment valproic acid is used in complex combined therapy regimens. Treatment of schizophrenia patients with valproate increases the BDNF level. Since it is not yet clear whether the BDNF protein levels measured in serum samples and in the brain correlate, we investigated valproate effects on the cultured neurons Bdnf transcription level. The primary neuron-glia culture was obtained from the cerebellum of 8-9-day-old Wistar rats. Valproic acid was added to the neurons (at a concentration of 50 µg/ml), oxidative stress was stimulated by 40 µMof H2O2, and injury was caused by mechanical damage to the neuron culture. It was shown that valproic acid in 3-24 hours increases the transcriptional activity of the Bdnf and Ngf (nerve growth factor) genes 2–2.5-fold (p<0.01) and approximately 1.5-fold (p<0.01), respectively. Mechanical trauma, unlike oxidative stress, activates the transcriptional activity of the Ngf and Bdnf genes (p<0.01). However, under oxidative stress and mechanical damage to neurons, the effect of valproic acid on the Ngf and Bdnf genes expression was insignificant. Fluorescence microscopy analysis using specific antibodies to neurons (anti-Map-2) showed that in the presence of valproic acid, the number of neuronal processes and contacts between them significantly increased. Evidently, valproate addition to antipsychotics can be effective for the overall clinical response. Relatively little research has been done on the signaling pathways in neurons that are activated by the valproic acid. However, we have obtained evidence of activation of the Ngf and Bdnf genes transcription in cultured neurons in vitro. We also found that in the presence of valproic acid, the number of neuronal processes and contacts between them significantly increased. However, we have also found that the oxidative stress accompanying the schizophrenia can significantly reduce the valproic acid effect on the Ngf and Bdnf genes expression. The results of the study may be potentially useful for new schizophrenia therapy strategies development.
COVID-LIBERTY, A Machine Learning Computational Framework for the Study of the Covid-19 Pandemic in Europe. Part 2: Setting up the Framework with Ensemble Modeling
Authors: Christakis Nicholas , Tirchas Panagiotis , Politis Michael , Achladianakis Minas , Avgenikou Eleftherios , Kossioris George
Published: September 2021

The Covid-19 pandemic has caused within a period of one year and eight months over 200,000,000 infections and more than 4,000,000 deaths. It is of paramount importance to design powerful and robust tools in order to be able to predict the evolution of the disease. In this paper, the computational framework COVID-LIBERTY is introduced, in order to assist the study of the pandemic in Europe. In Part 1, important parameters that should be taken into consideration and their parametrizations were given, as well as the details and mathematics of the computational engine of COVID-LIBERTY, a feed-forward, back-propagation Artificial Neural Network. In Part 2, the CPRT index is introduced, the framework setup around the Artificial Neural Network is presented and the algorithm of ensemble modeling is discussed, which improves the accuracy of the predictions. In the simulations, 4 European countries with similar population numbers were considered. The capabilities of the COVID-LIBERTY framework for accurate predictions for periods up to 19 days will be demonstrated.
Análisis de los hábitos de estudio en educación media superior en estudiantes de agronomía.
Authors: Peña Escalona Fleider L. , Chávez Arellano María Eugenia , Victorino Ramírez Liberio , González Garduño Roberto
Published: September 2021

El objetivo fue analizar los hábitos de estudios (HE) en estudiantes de agronomía en educación media superior. Se aplicó una encuesta con seis escalas: Lugar de estudio (LUG), planificación de estudio (PLA), atención en la sala de estudio (ATE), técnicas de estudio (TEC), trabajos (TRA) y actitud general (ACT). Se utilizaron 343 registros de estudiantes de las sedes en Mérida, Veracruz, Tabasco y Texcoco. Los datos se analizaron con el procedimiento de rangos de Friedman. Las escalas ACT, TEC y ATE tuvieron valores de 73 a 78 %, mientras que TRA, LUG y PLA tuvieron 57.7, 60 y 34 %, respectivamente, lo que implica que los estudiantes deben mejorar sus trabajos, su lugar de estudio y planear sus actividades académicas.
Caracterización epistemológica de la formación de pregrado de la carrera Licenciatura en Educación, Logopedia, en la Universidad de Granma, Cuba.
Authors: Rodríguez Vázquez Clara María , Figueredo Vila Elba Rosa
Published: September 2021

La formación de pregrado del estudiante de la carrera Licenciatura en Educación, Logopedia, demanda del desarrollo de competencias comunicativas, dentro de las cuales ocupa un lugar destacado la comunicación asertiva, como condición para conformar el sentido y significado de la profesión a partir de la influencia que sobre él ejercen los diversos factores, el conjunto de actividades curriculares en las que se involucra y su incidencia desde la práctica laboral, donde asume roles que connotan su formación profesional. En tal sentido, el objetivo del presente artículo radica en congregar los principales fundamentos epistémicos que sustentan el proceso de formación de pregrado del licenciado en Educación, Logopedia, con énfasis en la comunicación asertiva, en la Universidad de Granma, Cuba.
El Modelo Educativo basado en Competencias: Factor clave en la Educación Superior de las Universidades Politécnicas de México.
Authors: Manzur Quiroga Silvia Cristina , Balcázar González Alejandro , Ponce Cruz Monserrath
Published: September 2021

En la actualidad, uno de los retos que enfrentan las Universidades Politécnicas es tener espacios de aprendizaje que garanticen la adopción de competencias que demanda el mercado laboral; por ello, el uso de Entornos Virtuales de Aprendizaje, surge como una herramienta clave para el desarrollo de habilidades técnicas y genéricas, además de propiciar el trabajo colaborativo en la construcción del conocimiento, donde es necesario resaltar la importancia de los actores involucrados (alta dirección, docentes y estudiantes). El presente trabajo dirige su atención a estos aspectos de interés para una mejor atención a los procesos que se desarrollan en ellas.
Bases neuropsicofisiológicas del proceso de aprendizaje del lenguaje escrito.
Authors: Labrada Estrada Luis Enrique , Diéguez Corría Olemma Elvira , Rodríguez Aguilar Yusleidys
Published: September 2021

El conocimiento por parte de los educadores de las bases neuropsicofisiológicas de la lectura y la escritura permite que puedan influir en un adecuado proceso de adquisición del lenguaje escrito en los niños, lo cual contribuye a disminuir la inseguridad, frustración, deserción escolar que actualmente existe en las escuelas; también permite evitar problemas de aprendizaje y de conducta. Con un enfoque psicofisiológico se tratan los factores que posibilitan el desarrollo del lenguaje escrito y algunas de las alteraciones que se pueden presentar cuando no son estimulados correctamente desde las primeras edades.
Sobre la discusión filosófica del término educación física: una perspectiva ecléctica.
Authors: Mujica Johnson Felipe Nicolás
Published: September 2021

La educación física moderna es una actividad pedagógica que surge influenciada por una perspectiva filosófica idealista, que favoreció su enfoque higienista y utilitario. Con el tiempo dicha concepción filosófica ha sido relativizada, dando lugar a una discusión filosófica donde se enfrentan las miradas objetivista y subjetivista. En este artículo se abordan ambas concepciones y se incluye una nueva mirada conceptual; en concreto, la perspectiva ecléctica que encuentra sus bases filosóficas en la corriente fenomenológica, existencialista y realista. De este modo, se concluye que el ámbito físico del ser humano responde a una síntesis entre aspectos objetivos y subjetivos, el cual puede ser educado de manera intencionada y con mayor protagonismo que en otros procesos educativos.
Estudio etnobotánica en especies medicinales, sus usos e intervenciones de enfermería en la comunidad Ramosloma, Ecuador.
Authors: Gómez Martínez Nairovys , Gómez Martínez Nayaris , Rodríguez Guerra Yoel , Casarreal Guerra Ana Martha , Vilema Vizuete Germania Elisabeth
Published: September 2021

La enfermería como ciencia siente la necesidad de conocer el origen, contexto y actuación de las plantas medicinales. Describir las acciones de enfermería desde el conocimiento de la etnobotánica en especies medicinales fue el objetivo de la investigación descriptiva, transversal. La muestra quedó constituida por 163 habitantes que cumplieron con los criterios de inclusión y exclusión. Variables estudiadas: edad, sexo, forma de obtención del conocimiento, número de especies conocidas, y actividades de enfermería. El 65,03% de la muestra perteneció al sexo femenino y el 12,26 % de conocimiento, el 96,94 % de las acciones de enfermerías realizadas fueron en edades de 78 años y más. Existió correlación entre las acciones de enfermería y la forma de conocimiento empírica y médica.