bluuebunny/crossref_metadata_2025 huggingface dataset:
Weaver syndrome and EZH2 mutations: Clarifying the clinical phenotype
Authors: Tatton‐Brown Katrina , Murray Anne , Hanks Sandra , Douglas Jenny , Armstrong Ruth , Banka Siddharth , Bird Lynne M. , Clericuzio Carol L. , Cormier‐Daire Valerie , Cushing Tom , Flinter Frances , Jacquemont Marie‐Line , Joss Shelagh , Kinning Esther , Lynch Sally Ann , Magee Alex , McConnell Vivienne , Medeira Ana , Ozono Keiichi , Patton Michael , Rankin Julia , Shears Debbie , Simon Marleen , Splitt Miranda , Strenger Volker , Stuurman Kyra , Taylor Clare , Titheradge Hannah , Van Maldergem Lionel , Temple I. Karen , Cole Trevor , Seal Sheila ,   Childhood Overgrowth Consortium, Rahman Nazneen
Published: November 2013

Weaver syndrome, first described in 1974, is characterized by tall stature, a typical facial appearance, and variable intellectual disability. In 2011, mutations in the histone methyltransferase, EZH2, were shown to cause Weaver syndrome. To date, we have identified 48 individuals with EZH2 mutations. The mutations were primarily missense mutations occurring throughout the gene, with some clustering in the SET domain (12/48). Truncating mutations were uncommon (4/48) and only identified in the final exon, after the SET domain. Through analyses of clinical data and facial photographs of EZH2 mutation‐positive individuals, we have shown that the facial features can be subtle and the clinical diagnosis of Weaver syndrome is thus challenging, especially in older individuals. However, tall stature is very common, reported in >90% of affected individuals. Intellectual disability is also common, present in ∼80%, but is highly variable and frequently mild. Additional clinical features which may help in stratifying individuals to EZH2 mutation testing include camptodactyly, soft, doughy skin, umbilical hernia, and a low, hoarse cry. Considerable phenotypic overlap between Sotos and Weaver syndromes is also evident. The identification of an EZH2 mutation can therefore provide an objective means of confirming a subtle presentation of Weaver syndrome and/or distinguishing Weaver and Sotos syndromes. As mutation testing becomes increasingly accessible and larger numbers of EZH2 mutation‐positive individuals are identified, knowledge of the clinical spectrum and prognostic implications of EZH2 mutations should improve. © 2013 Wiley Periodicals, Inc.
Neurophysiologic effect of GWAS derived schizophrenia and bipolar risk variants
Authors: Hall Mei‐Hua , Levy Deborah L. , Salisbury Dean F. , Haddad Steve , Gallagher Patience , Lohan Mary , Cohen Bruce , Öngür Dost , Smoller Jordan W.
Published: November 2013

Genome‐wide association studies (GWAS) have identified multiple single nucleotide polymorphisms (SNPs) as disease associated variants for schizophrenia (SCZ), bipolar disorder (BPD), or both. Although these results are statistically robust, the functional effects of these variants and their role in the pathophysiology of SCZ or BPD remain unclear. Dissecting the effects of risk genes on distinct domains of brain function can provide important biological insights into the mechanisms by which these genes may confer illness risk. This study used quantitative event related potentials to characterize the neurophysiological effects of well‐documented GWAS‐derived SCZ/BPD susceptibility variants in order to map gene effects onto important domains of brain function. We genotyped 199 patients with DSM‐IV diagnoses of SCZ or BPD and 74 healthy control subjects for 19 risk SNPs derived from previous GWAS findings and tested their association with five neurophysiologic traits (P3 amplitude, P3 latency, N1 amplitude, P2 amplitude, and P50 sensory gating responses) known to be abnormal in psychosis. The TCF4 SNP rs17512836 risk allele showed a significant association with reduced auditory P3 amplitude (P = 0.00016) after correction for multiple testing. The same allele was also associated with delayed P3 latency (P = 0.005). Our results suggest that a SCZ risk variant in TCF4 is associated with neurophysiologic traits thought to index attention and working memory abnormalities in psychotic disorders. These findings suggest a mechanism by which TCF4 may contribute to the neurobiological basis of psychotic illness. © 2013 Wiley Periodicals, Inc.
Nanoporentechniken zur Sequenzierung und Detektion von Nukleinsäuren
Authors: Ying Yi‐Lun , Zhang Junji , Gao Rui , Long Yi‐Tao
Published: November 2013

Nanoporentechniken, die die Funktionen natürlicher Ionenkanäle nachahmen, sind nützliche Methoden für den Einzelmolekülnachweis. Das Verfahren erlaubt die selektive Analyse von Nukleinsäuren in Echtzeit und im Hochdurchsatz. Zwei Arten von Nanoporen finden Anwendung: biologische Nanoporen und Festkörpernanoporen. Dieser Kurzaufsatz beleuchtet die Grundlagen und jüngsten Fortschritte bei der nanoporenbasierten Sequenzierung und Detektion von Nukleinsäuren. Außerdem wird eine neuartige, erst kürzlich eingeführte Nanoporentechnik für die Analyse von Biomolekülen vorgestellt.
Dehydrierende Kreuzkupplungen von C‐H‐Bindungen: vielseitige Verfahren zur Bildung von C‐C‐Bindungen
Authors: Girard Simon A. , Knauber Thomas , Li Chao‐Jun
Published: November 2013

In den vergangenen zehn Jahren wurde eine beeindruckende Zahl an Verfahren entwickelt, die den selektiven Aufbau von C‐C‐Bindungen über die direkte Verknüpfung von zwei unterschiedlichen C‐H‐Bindungen unter oxidativen Bedingungen ermöglichen. Diesen Methoden ist gemeinsam, dass die reaktiven Zwischenstufen durch Aktivierung der beiden C‐H‐Bindungen in situ gebildet werden. Diese Strategie wurde von der Gruppe von Li als dehydrierende Kreuzkupplung (CDC, “cross‐dehydrogenative coupling”) eingeführt und eröffnet abfallarme Synthesealternativen zu klassischen Kupplungsverfahren, die sich auf die Verwendung von vorfunktionalisierten Ausgangsstoffen stützen. Dieser Aufsatz hebt die Fortschritte auf dem Gebiet der dehydrierenden C‐C‐Bindungsknüpfungen hervor und liefert einen umfassenden Überblick über die vorhandenen Verfahren.
Foldamer‐Mediated Remote Stereocontrol: >1,60 Asymmetric Induction
Authors: Byrne Liam , Solà Jordi , Boddaert Thomas , Marcelli Tommaso , Adams Ralph W. , Morris Gareth A. , Clayden Jonathan
Published: November 2013

An N‐terminal L‐α‐methylvaline dimer induces complete conformational control over the screw sense of an otherwise achiral helical peptide foldamer formed from the achiral quaternary amino acids Aib and Ac6c. The persistent right‐handed screw‐sense preference of the helix enables remote reactive sites to fall under the influence of the terminal chiral residues, and permits diastereoselective reactions such as alkene hydrogenation or iminium ion addition to take place with 1,16‐, 1,31‐, 1,46‐ and even 1,61‐asymmetric induction. Stereochemical information may be communicated in this way over distances of up to 4 nm.
Preliminary evaluation of packaging‐content interactions: Mechanical and physicochemical characterization of polylactide bottles
Authors: Capra Priscilla , Briasco Benedetta , Sorrenti Milena , Catenacci Laura , Sachet Marco , Perugini Paola
Published: November 2013

Biodegradable materials as polylactide (PLA) are very interesting for cosmetic packaging application. However, these polymers, under environmental conditions or/and chemical treatments, can undergo “aging,” compromising their performances such as container. The aim of this study was the evaluation of mechanical, physicochemical, and organoleptic properties of PLA bottles present in the cosmetic market. In particular, mechanical tests and thermal analyses were applied to study the PLA container degradation under stressed physicochemical conditions. Calorimetric and morphological analyses were applied to evaluate differences between internal and external surface of containers. Results highlighted that the heating process together with chemical treatment determined a significant modification on polymer, leading to a more resistant and fragile material, whereas the only physical or chemical treatment alone showed a plasticizing effect. In conclusion, this study represents a start point to evaluate content–packaging interactions to optimize the choice of PLA polymer as cosmetic packaging. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40067.
Green synthesis and characterization of phosphorus flame retardant crosslinking agents for epoxy resins
Authors: Toldy Andrea , Szolnoki Beáta , Csontos István , Marosi György
Published: November 2013

The flame‐retardant efficacy of phosphorus‐containing reactive amine hardeners for epoxy resins is well‐known; however their synthesis often applies hazardous, objectionable reagents. The aim of this work is to develop an effective synthesis method for the preparation of P‐containing amines, which can act as flame‐retardant crosslinking agent in epoxy resins. The syntheses and testing of an aliphatic and two aromatic amines are described: curing properties, glass transition temperature, thermal stability, and flame‐retardant performance of the amines are studied. On the basis of these results, the scaling‐up and the optimization of the synthesis of the phosphorus‐containing aliphatic amine hardener in ReactIR™ in situ FTIR apparatus is discussed. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40105.
Magnetic Investigations of Buried Palaeohearths Inside a Palaeolithic Cave (Lazaret, Nice, France)
Authors: Jrad Abir , Quesnel Yoann , Rochette Pierre , Jallouli Chokri , Khatib Samir , Boukbida Hanane , Demory François
Published: November 2013

We present a magnetic study of palaeohearths within Lazaret cave (Nice, France) that demonstrates how to recognize fired structures in similar geological contexts. Using magnetic field and susceptibility mapping, excavated and potentially still‐buried palaeohearths of the cave are investigated. Our study reveals some difficulties in conducting a magnetic field survey to detect combustion features in a cave due to noise and ambiguities in anomaly assignment. To overcome these difficulties, discrete measurements and a specific post‐processing methodology were applied to remove the magnetic noise generated by surrounding artificial sources. In addition, experimental and numerical modelling constrained by laboratory examinations of the magnetic mineralogy were performed to better identify the magnetic imprint of such fireplaces. We confirm that a short‐term fireplace produces a thin ash‐bearing layer characterized by a high magnetic susceptibility and a high frequency dependence due to a large proportion of grains of pseudo‐single‐domain (PSD) size. Such a burnt soil layer is the main source of the ca. 50 nT amplitude magnetic field anomaly at a sensor height of 15 cm observed over the excavated palaeohearth, as well as over an experimental hearth. Copyright © 2013 John Wiley & Sons, Ltd.
The wisdom of citing scientists
Authors: Bornmann Lutz , Marx Werner
Published: November 2013

This Brief Communication discusses the benefits of citation analysis in research evaluation based on Galton's “Wisdom of Crowds” (1907). Citations are based on the assessment of many which is why they can be considered to have some credibility. However, we show that citations are incomplete assessments and that one cannot assume that a high number of citations correlates with a high level of usefulness. Only when one knows that a rarely cited paper has been widely read is it possible to say—strictly speaking—that it was obviously of little use for further research. Using a comparison with “like” data, we try to determine that cited reference analysis allows for a more meaningful analysis of bibliometric data than times‐cited analysis.
Hazard ratio estimation for two‐sample case under interval‐censored failure time data
Authors: Feng Yanqin , Sun Jianguo
Published: November 2013

This paper discusses two‐sample comparison in the case of interval‐censored failure time data. For the problem, one common approach is to employ some nonparametric test procedures, which usually give somep‐values but not a direct or exact quantitative measure of the survival or treatment difference of interest. In particular, these procedures cannot provide a hazard ratio estimate, which is commonly used to measure the difference between the two treatments or samples. For interval‐censored data, a few nonparametric test procedures have been developed, but it does not seem to exist as a procedure for hazard ratio estimation. Corresponding to this, we present two procedures for nonparametric estimation of the hazard ratio of the two samples for interval‐censored data situations. They are generalizations of the corresponding procedures for right‐censored failure time data. An extensive simulation study is conducted to evaluate the performance of the two procedures and indicates that they work reasonably well in practice. For illustration, they are applied to a set of interval‐censored data arising from a breast cancer study.
Tensile properties of a morphologically split supraspinatus tendon
Authors: Matsuhashi Tomoya , Hooke Alexander W. , Zhao Kristin D. , Goto Akira , Sperling John W. , Steinmann Scott P. , An Kai‐Nan
Published: November 2013

The supraspinatus tendon consists morphologically of two sub‐regions, anterior and posterior. The anterior sub‐region is thick and tubular while the posterior is thin and strap‐like. The purpose of this study was to compare the structural and mechanical properties of the anterior and posterior sub‐regions of the supraspinatus tendon. The supraspinatus tendons from seven human cadaveric shoulders were morphologically divided into the anterior and posterior sub‐regions. Length, width, and thickness were measured. A servo‐hydraulic testing machine (MTS Systems Corporation, Minneapolis, MN) was used for tensile testing. The maximal load at failure, modulus of elasticity and ultimate tendon stress were calculated. Repeated measures were used for statistical comparisons. The mean anterior tendon cross‐sectional area was 47.3 mm2 and the posterior was 32.1 mm2. Failure occurred most often at the insertion site: anterior (5/7) and posterior (6/7). All parameters of the anterior sub‐region were significantly greater than those of the posterior sub‐region. The moduli of elasticity at the insertion site were 592.4 MPa in the anterior sub‐region and 217.7 MPa in the posterior (P = 0.01). The ultimate failure loads were 779.2 N in the anterior sub‐region and 335.6 N in the posterior (P = 0.003). The ultimate stresses were 22.1 MPa in the anterior sub‐region and 11.6 MPa in the posterior (P = 0.008). We recognized that the anterior and posterior sub‐regions of the SSP tendon have significantly different mechanical properties. In a future study, we need to evaluate how best to repair an SSP tendon considering these region‐specific properties. Clin. Anat. 27:702–706, 2014. © 2013 Wiley Periodicals, Inc.
Optimal duration of dual antiplatelet therapy following treatment with the endeavor zotarolimus‐eluting stent in real‐world Japanese patients with coronary artery disease (OPERA): Study design and rationale
Authors: Nakamura Masato , Nanto Shinsuke , Hirayama Atsushi , Takayama Tadateru , Nishikawa Masakatsu , Kimura Kazuo , Morita Satoshi , Aizawa Tadanori , Asano Ryuta , Matsumaru Yuji , Hamada Chikuma , Isshiki Takaaki ,   for the OPERA Steering Committee and Investigators
Published: November 2013

Background: In patients with coronary artery disease (CAD), there is an increasing therapeutic need among interventional cardiologists to conduct dual antiplatelet therapy (DAPT) whose duration is shorter than current guideline‐recommended 6–12 months after the implantation of drug‐eluting stents. However, no clinical grounds sufficient to rationalize the need are available. Objectives: To define the optimal duration of DAPT and to examine the safety and efficacy of the Endeavor zotarolimus‐eluting stent (E‐ZES) in real‐world Japanese patients with CAD. Study design: The present prospective, nonrandomized, multicenter, controlled study is uniquely designed to examine the analysis set to be formulated after integrating two different databases consisting of the following two study arms: the 3‐month DAPT arm, in which 1,210 patients were consecutively enrolled at 106 medical institutions; and the 12‐month DAPT arm, in which 1,210 patients will be consecutively extracted from the Endeavor Japan post‐marketing surveillance at 60 medical institutions. The primary endpoint is “net adverse cardiac and cerebrovascular events—death, myocardial infarction, cerebrovascular accident, and major bleeding)” at 12 months after implantation. The secondary endpoints are as follows: major adverse cardiac events at 1, 3, 6, 9, and 12 months after implantation; target vessel revascularization and target lesion revascularization at 9 and 12 months after implantation; and stent thrombosis, DAPT compliance, and bleeding events at 12 months after implantation. Noninferiority in the E‐ZES's profiles between the study arms will be investigated. Conclusions: The present study will provide insight into the optimal duration of DAPT after the E‐ZES implantation in individual, real‐world patients with CAD. © 2013 Wiley Periodicals, Inc.
Characterization of a Novel Flat‐Panel Airlift Photobioreactor With an Internal Heat Exchanger
Authors: Kochem Luce Helena , Da Fré Nicéia Chies , Redaelli Cristiane , Rech Rosane , Marcílio Nilson Romeu
Published: November 2013

A novel flat‐panel airlift photobioreactor with an internal heat exchanger (FPA‐IHE) separating the riser and downcomer zones was characterized. The proposed FPA‐IHE has working volume of 2.2 L, height of 450 mm and light path of 50 mm. The overall heat transfer coefficients for the internal heat exchanger and the external surface of the reactor were 47.0 W m–2K–1 and 7.1 W m–2K–1, respectively. The mass transfer coefficient increased with an increase in the volumetric power input until a value of 0.01 s–1. The mixture time decreased with the increase in the superficial gas velocity of the riser. The circulation time ranged from 5 to 6 s. The specific growth rates of Dunaliella tertiolecta and Chlorella minutissima were high, 0.77 d–1 and 0.67 d–1, respectively; thus, the FPA‐IHE photobioreactor is a promising environment for the development of highly productive processes using microalgae.
Chiral Photoresponsive Tetrathiazoles That Provide Snapshots of Folding States
Authors: Nakashima Takuya , Yamamoto Kyohei , Kimura Yuka , Kawai Tsuyoshi
Published: November 2013

Herein, we designed chiral photoresponsive tetra(2‐phenylthiazole)s, which induce a diastereoselective 6π‐electrocyclization reaction in a helically folded structure to freeze the conformational interconversions. The folding conformation with one helical turn of tetra(2‐phenylthiazole)s was supported by multiple intramolecular noncovalent interactions including vicinal S⋅⋅⋅N interheteroatom interactions and CH–π and π–π stacking interactions between nonadjacent units, as found in X‐ray crystal structures as well as quantum chemical calculations. The introduction of a chiral group at both ends of tetra(2‐phenylthiazole) dictates the preferential folding into a one‐handed helix conformation by the simultaneous operation of S⋅⋅⋅O and multiple CH–π interactions that involve the chiral end groups. Since the tetra(2‐phenylthiazole)s possess two equivalent photoreactive 6π‐electron systems and the folded conformation is suitable for photoinduced electrocyclization reaction, they undergo a photocyclization reaction in a stereoselective manner to memorize the chirality of the helix in a resulting diastereomeric closed form.
Comparison of Gas Sorption Properties of Neutral and Anionic Metal–Organic Frameworks Prepared from the Same Building Blocks but in Different Solvent Systems
Authors: Choi Myung‐Ho , Park Hye Jeong , Hong Dae Ho , Suh Myunghyun Paik
Published: November 2013

Two different 3D porous metal–organic frameworks, [Zn4O(NTN)2]⋅10 DMA⋅7 H2O (SNU‐150) and [Zn5(NTN)4(DEF)2][NH2(C2H5)2]2⋅8 DEF⋅6 H2O (SNU‐151), are synthesized from the same metal and organic building blocks but in different solvent systems, specifically, in the absence and the presence of a small amount of acid. SNU‐150 is a doubly interpenetrated neutral framework, whereas SNU‐151 is a non‐interpenetrated anionic framework containing diethylammonium cations in the pores. Comparisons of the N2, H2, CO2, and CH4 gas adsorption capacities as well as the CO2 adsorption selectivity over N2 and CH4 in desolvated SNU‐150′ (BET: 1852 m2 g−1) and SNU‐151′ (BET: 1563 m2 g−1) samples demonstrate that the charged framework is superior to the neutral framework for gas storage and gas separation, despite its smaller surface area and different framework structure.
ChemInform Abstract: A Luminescent Material: La3Cl(CN2)O3 Doped with Eu3+ or Tb3+ Ions.
Authors: Kubus Mariusz , Enseling David , Juestel Thomas , Meyer H.‐Juergen
Published: November 2013

The new title compound is synthesized by solid state reaction of LaOCl and Li2(CN2) (750 °C, 2 d) and characterized by single crystal XRD, FTIR spectroscopy, and luminescence measurements.
ChemInform Abstract: Ternary Antimonides RE4T7Sb6 (RE: Gd—Lu; T: Ru, Rh) with Cubic U4Re7Si6‐Type Structure.
Authors: Schellenberg Inga , Rodewald Ute Ch. , Schwickert Christian , Eul Matthias , Poettgen Rainer
Published: November 2013

The title compounds are prepared by arc‐melting of the elements followed by annealing (evacuated quartz ampoules, 1370 K, 1 h).
ChemInform Abstract: High‐Pressure Synthesis and Characterization of the Rare‐Earth Fluoride Borate LaB2O4F.
Authors: Hinteregger Ernst , Kocsis Krisztina , Hofer Thomas S. , Heymann Gunter , Perfler Lukas , Huppertz Hubert
Published: November 2013

LaB2O4F is prepared from stoichiometric mixtures of La2O3, B2O3, and LaF3 under high‐pressure/high‐temperature conditions (BN crucibles in multianvil press, 1300 °C, 1.1 GPa).
ChemInform Abstract: Monomer and Dimer of Mono‐titanium(IV)‐Containing α‐Keggin Polyoxometalates: Synthesis, Molecular Structures, and pH‐Dependent Monomer—Dimer Interconversion in Solution.
Authors: Matsuki Yusuke , Mouri Yuki , Sakai Yoshitaka , Matsunaga Satoshi , Nomiya Kenji
Published: November 2013

Compounds (III) and (IV) are characterized by single crystal XRD, FTIR, CPMAS 31P NMR, and solution 31P and 183W NMR spectroscopy.
ChemInform Abstract: Copper and Zinc Substitutions in Clathrates of Tin: Synthesis, Structural Characterization, and Physical Properties of A8Cu2.67Sn43.33 and A8Zn4Sn42 (A: K, Rb, Cs) with the Type‐I Structure.
Authors: Schaefer Marion C. , Bobev Svilen
Published: November 2013

The new compounds K8Cu2.77Sn43.23, Rb8Cu2.8Sn43.2, Cs8Cu2.69Sn43.31, K8Zn3.78Sn42.22, Rb8Zn3.52Sn42.48, and Cs8Zn3.44Sn42.56 are prepared in quantitative yield by arc melting of the elements with Sn acting as self‐flux, followed by heating at 600 °C for 15 h.
ChemInform Abstract: Synthesis and Structure of KPbBP2O8 — A Congruent Melting Borophosphate with Nonlinear Optical Properties.
Authors: Li Hongyi , Zhao Yi , Pan Shilie , Wu Hongping , Yu Hongwei , Zhang Fangfang , Yang Zhihua , Poeppelmeier Kenneth R.
Published: November 2013

The title compound is prepared by solid state reaction of KNO3, PbO, H3BO3, and NH4H2PO4 (1.
ChemInform Abstract: Early‐Lanthanide Complexes with All‐Inorganic Macrocyclic Polyoxovanadate Ligands.
Authors: Nishio Masaki , Inami Shinnosuke , Hayashi Yoshihito
Published: November 2013

Compound (III)·3MeCN and (Et4N)7[CeV10O30]·3MeCN crystallize in the orthorhombic space group P212121 with Z = 4.
ChemInform Abstract: Two Members of the {X4Nb16O56} Family (X: Ge, Si) Based on [(GeOH)2Ge2Nb16H2O54] 12‐ and [K(GeOH)2Ge2Nb16H3O54 ]10‐.
Authors: Zhang Xin , Liu Shu‐Xia , Li Shu‐Jun , Gao Yu‐Huan , Wang Xue‐Na , Tang Qun , Liu Yi‐Wei
Published: November 2013

(III) and (VI) are characterized by single crystal XRD, IR and UV/VIS diffuse reflectance spectroscopy, and electrochemical measurements.
ChemInform Abstract: Monolacunary Germanomolybdates Binding with Transition‐Metal Ions (CoII, NiII, and MnII) in Aqueous Solution: Synthesis, Crystal Structures, and Magnetic Properties.
Authors: Wang Na , Li Fengyan , Wang Yuchao , Xu Lin , Cui Keyu , Xu Bingbing
Published: November 2013

Compounds (IIIa—c) are characterized by single crystal XRD, IR and UV/VIS spectroscopy, cyclic voltammetry, and magnetic measurements.
ChemInform Abstract: Four Members of the Sandwich‐Type Polytungstophosphate Family Based on Pentalacunary [HPW7O28]8‐ Building Blocks.
Authors: Zhang Dongdi , Zhang Yanhui , Zhao Juan , Ma Pengtao , Wang Jingping , Niu Jingyang
Published: November 2013

The new compounds (III), (V), and (VII) are characterized by single crystal XRD, IR and UV/VIS spectroscopy, and cyclic voltammetry.
ChemInform Abstract: Novel O,N,N,O‐Tetradentate Ligand from Tartaric Acid.
Authors: Balaraman Kaluvu , Vasanthan Ravichandran , Kesavan Venkitasamy
Published: November 2013

The ligand is applied for asymmetric palladium catalyzed alkylation of allylic acetates.
ChemInform Abstract: Asymmetric Aldol Reactions in Caprolactam—Quaternary Ammonium Salt Coordination Ionic Liquid Catalyzed by L‐Pro‐L‐Trp.
Authors: Zhang Bao‐Hua , He Jing‐Yu , Liu Si‐Jie , Shi Lan‐Xiang
Published: November 2013

A direct asymmetric aldol reaction of aldehydes (I) and acetone (II) catalyzed by a dipeptide is achieved in β‐caprolactam‐quaternary ammonium salt coordination ionic liquid media in good yields and enantioselectivities.
ChemInform Abstract: An Efficient and Scalable Room Temperature Aerobic Alcohol Oxidation Catalyzed by Iron Chloride Hexahydrate/Mesoporous Silica Supported TEMPO.
Authors: Wang Lianyue , Li Jun , Zhao Xiaoping , Lv Ying , Zhang Hengyun , Gao Shuang
Published: November 2013

The immobilized TEMPO catalyst can be recycled and reused for at least four runs without significant loss of activity (yields determined by GC).
ChemInform Abstract: Azidation of β‐Keto Esters and Silyl Enol Ethers with a Benziodoxole Reagent.
Authors: Vita Maria Victoria , Waser Jerome
Published: November 2013

The efficient azidation of β‐keto esters and silyl enol ethers using a benziodoxole‐derived azide transfer reagent is reported.
ChemInform Abstract: Synthesis and Characterization of Sterically Enlarged Hoveyda‐Type Olefin Metathesis Catalysts.
Authors: Shahane Saurabh , Toupet Loic , Fischmeier Cedric , Bruneau Christian
Published: November 2013

In view of the utilization of catalysts in nanofiltration processes a series of modified 2nd generation Hoveyda‐Grubbs‐type metathesis catalysts are synthesized.
ChemInform Abstract: Cyclodehydration of N‐(Aminoalkyl)benzamides under Mild Conditions with a Hendrickson Reagent Analogue.
Authors: Loughlin Wendy A. , Jenkins Ian D. , Petersson Maria J.
Published: November 2013

Cyclohydration of benzamides occurs in two steps using phosphinium anhydrides.
ChemInform Abstract: Development of Asymmetric Deacylative Allylation.
Authors: Grenning Alexander J. , Van Allen Christie K. , Maji Tapan , Lang Simon B. , Tunge Jon A.
Published: November 2013

A simple, robust, and new method for the preparation of allylated tetralones is developed.
ChemInform Abstract: Copper‐Catalyzed Regioselective Fluorination of Allylic Halides.
Authors: Zhang Zuxiao , Wang Fei , Mu Xin , Chen Pinhong , Liu Guosheng
Published: November 2013

This reaction requires a heteroatom functional group in the substrate to give good reactivity and regioselectivity.
ChemInform Abstract: Modular Bipyridine Ligands Coupled with Cinchona Alkaloids for Cu(II)‐Catalyzed Asymmetric Henry Reactions.
Authors: Liu Ming , Ma Shijun , Tian Zhiqing , Wu Hao , Wu Lulu , Xu Xiufang , Huang Yaodong , Wang Yongmei
Published: November 2013

Novel bipyridine substituted cinchona ligands are prepared and successfully applied to Cu(II)‐catalyzed asymmetric Henry reactions.
ChemInform Abstract: Palladium‐Catalyzed Intermolecular Aminoacetoxylation of Alkenes and the Influence of PhI(OAc)2 on Aminopalladation Stereoselectivity.
Authors: Martinez Claudio , Wu Yichen , Weinstein Adam B. , Stahl Shannon S. , Liu Guosheng , Muniz Kilian
Published: November 2013

In comparison to related reactions under aerobic conditions, the utilization of Ph—I(OAc)2 changes the aminopalladation step from a cis‐selective process to a trans‐selective one.
ChemInform Abstract: A New Strategy for the Construction of α‐Amino Acid Esters via Decarboxylation.
Authors: Zhang Jie , Jiang Jiewen , Li Yuling , Zhao Yun , Wan Xiaobing
Published: November 2013

This method is characterized by readily accessible starting materials, the lack of moisture sensitivity, environmentally benign reaction conditions, and a wide substrate scope.
ChemInform Abstract: Asymmetric Syntheses of Enantiopure C(5)‐Substituted Transpentacins via Diastereoselective Ireland—Claisen Rearrangements.
Authors: Davies Stephen G. , Fletcher Ai M. , Roberts Paul M. , Thomson James E. , Zammit Charlotte M.
Published: November 2013

Asymmetric syntheses of amino‐methyl‐cyclopentanecarboxylic acids are achieved in 9 steps from commercially available starting materials via Ireland‐Claisen rearrangement of β‐amino allyl esters (I), followed by ring‐closure metathesis, reduction and deprotection.
ChemInform Abstract: Synthesis of Multisubstituted Olefins Through Regio‐ and Stereoselective Silylborylation of an Alkynylboronate/Chemoselective Cross‐Coupling Sequences.
Authors: Jiao Jiao , Nakajima Kiyohiko , Nishihara Yasushi
Published: November 2013

A highly regio‐ and stereoselective silylborylation of alkynylboronate (I) is disclosed.
ChemInform Abstract: Rh(III)‐Catalyzed C—H Amidation Using Aroyloxycarbamates to Give N‐Boc Protected Arylamines.
Authors: Grohmann Christoph , Wang Honggen , Glorius Frank
Published: November 2013

The presented reaction proceeds under mild conditions with a broad functional group tolerance.
ChemInform Abstract: Expedient C—H Amidations of Heteroaryl Arenes Catalyzed by Versatile Ruthenium(II) Catalysts.
Authors: Thirunavukkarasu Vedhagiri S. , Raghuvanshi Keshav , Ackermann Lutz
Published: November 2013

Heteroaryl‐substituted arenes and heteroarenes are efficiently amidated through ruthenium‐catalyzed C—H bond functionalizations with a variety of sulfonyl azides.
ChemInform Abstract: Synthesis of Alkyl‐Ynol‐Ethers by “Anti‐Michael Addition” of Metal Alkoxides to β‐Substituted Alkynylsulfones.
Authors: Marzo Leyre , Parra Alejandro , Frias Maria , Aleman Jose , Garcia Ruano Jose Luis
Published: November 2013

Alkynyls bearing aryl or triisopropylsilyl groups are suitable substrates for the title synthesis.
ChemInform Abstract: Tandem Iminium/Copper Catalysis: Highly Enantioselective Synthesis of α,β‐Disubstituted Aldehydes.
Authors: Kim Ju‐Hye , Park Eun‐Jin , Lee Hwa‐Jung , Ho Xuan‐Huong , Yoon Hyo‐Sang , Kim Pilsoo , Yun Hoseop , Jang Hye‐Young
Published: November 2013

The title reaction proceeds through iminium‐catalyzed Michael addition followed by copper‐assisted addition of TEMPO in a one‐pot manner.
ChemInform Abstract: Facile Oxidation of Alcohols to Aldehydes or Ketones with 1‐Acetoxy‐5‐nitro‐1,2‐benziodoxole‐3(1H)‐one.
Authors: Iinuma Masataka , Moriyama Katsuhiko , Togo Hideo
Published: November 2013

The title reaction represents the first method for the effective oxidation of alcohols to aldehydes or ketones with a trivalent iodine reagent alone under mild conditions.
ChemInform Abstract: Gold Meets Rhodium: Tandem One‐Pot Synthesis of β‐Disubstituted Ketones via Meyer—Schuster Rearrangement and Asymmetric 1,4‐Addition.
Authors: Hansmann Max M. , Hashmi A Stephen K. , Lautens Mark
Published: November 2013

A novel and general Au/Rh tandem transformation providing β‐disubstituted ketones as valuable synthetic building blocks in high yields and enantioselectivities is disclosed.
ChemInform Abstract: Silver‐Mediated Methoxycarbonyltetrafluoroethylation of Arenes.
Authors: Hafner Andreas , Feuerstein Thomas J. , Braese Stefan
Published: November 2013

Several conversions of the triazene moiety into different functional groups are presented.
ChemInform Abstract: Copper‐Catalyzed Dehydrogenative Reaction: Synthesis of Amide from Aldehydes and Aminopyridine.
Authors: Yang Sizhuo , Yan Hao , Ren Xiaoyu , Shi Xiaokang , Li Jian , Wang Yuling , Huang Guosheng
Published: November 2013

A simple protocol using air as the oxidant is developed for the synthesis of benzamides via oxidative amidation of benzaldehydes with aminopyridine derivatives.
ChemInform Abstract: Synthesis of S‐Aryl Arenethiosulfonates from N,N‐Di(arenesulfonyl)hydrazines: Reduction of Sulfonyl Chlorides with an Organic Reagent.
Authors: Iwata Satoshi , Senoo Masato , Hata Takeshi , Urabe Hirokazu
Published: November 2013

The presented reaction is limited to N,N‐Di(arenesulfonyl)hydrazines and does not work with N,N‐Di(alkylsulfonyl)hydrazines.
ChemInform Abstract: Organocatalytic Asymmetric Sulfa‐Michael Addition of Thiols to α,β‐Unsaturated Hexafluoroisopropyl Esters: Expeditious Access to (R)‐Thiazesim.
Authors: Fang Xin , Li Jun , Wang Chun‐Jiang
Published: November 2013

Application of this method is demonstrated by the total synthesis of (R)‐Thiazesim (VI) that is obtained in 75% yield and 98% e.e.
ChemInform Abstract: Aerobic Oxysulfonylation of Alkenes Leading to Secondary and Tertiary β‐Hydroxysulfones.
Authors: Lu Qingquan , Zhang Jian , Wei Fuliang , Qi Yue , Wang Huamin , Liu Zhiliang , Lei Aiwen
Published: November 2013

The novel title reaction tolerates a wide range of functional groups and proceeds without any additional initiators.
ChemInform Abstract: Synthesis of Substituted Biaryls via Suzuki, Stille and Hiyama Cross‐Coupling and Homo‐Coupling Reactions by CN‐Dimeric and Monomeric ortho‐Palladated Catalysts.
Authors: Hajipour Abdol R. , Rafiee Fatemeh
Published: November 2013

The monomeric ortho‐palladated catalyst (DMPA) is successfully applied to the title coupling reactions [43 examples].
ChemInform Abstract: One‐Pot Synthesis of Novel Spiro[quinazoline/pyrimidine]ones via Multi Component Reaction.
Authors: Meshram Gangadhar , Wagh Pramod , Deshpande Shruti , Amratlal Vipul
Published: November 2013

A new and facile one‐pot method for synthesis of the title scaffolds is presented and further extended by employing two other reactive ketones instead of isatin.
ChemInform Abstract: Synthesis of cis‐C‐Iodo‐N‐tosyl‐aziridines Using Diiodomethyllithium: Reaction Optimization, Product Scope and Stability, and a Protocol for Selection of Stationary Phase for Chromatography.
Authors: Boultwood Tom , Affron Dominic P. , Trowbridge Aaron D. , Bull James A.
Published: November 2013

The excellent cis‐diastereoselective title synthesis provides a wide range of cis‐iodoaziridines including the first examples of alkyl‐substituted iodoaziridines (≥95 % ds.).
ChemInform Abstract: A Thioannulation Approach to Substituted Thiophenes from Morita—Baylis—Hillman Acetates of Acetylenic Aldehydes.
Authors: Reddy Chada Raji , Valleti Redi Rani , Reddy Motatipally Damoder
Published: November 2013

The new and versatile protocol for the title approach proceeds under mild and metal‐free reaction conditions and through a tandem allylic substitution/deacetylative thiocycloisomerization.
ChemInform Abstract: Highly Regioselective and Metal‐Free γ‐Addition of β‐Keto Esters to Isatins, Catalyzed by DABCO: Direct Access to Novel Class of Diversely Functionalized 3‐Hydroxy‐2‐oxindole Scaffolds.
Authors: Thakur Pramod Bhagwan , Sirisha Katukuri , Sarma Akella Venkata Subrahmanya , Nanubolu Jagadeesh Babu , Meshram Harshadas Mitaram
Published: November 2013

The DABCO catalyzed aldol reaction of isatins with β‐keto esters provides unexpected γ‐addition products with high regioselectivity.
ChemInform Abstract: Cyclization‐Carbonylation‐Cyclization Coupling Reaction of α, β‐Alkynic Hydrazones with Palladium(II)‐Bisoxazoline Catalyst.
Authors: Kusakabe Taichi , Sagae Hiroshi , Kato Keisuke
Published: November 2013

The title reaction affords symmetrical ketones (III) bearing two pyrazole groups and is general for a wide range of substrates.
ChemInform Abstract: Sequential [3 + 2] Cycloaddition/Air Oxidation Reactions: Triazoloyl Ion Assisted Oxidative Cleavage of Alkynes.
Authors: Ponpandian Thanasekaran , Muthusubramanian Shanmugam , Rajagopal Sridharan
Published: November 2013

Benzaldehyde or formaldehyde, respectively, are the byproducts in these reactions.
ChemInform Abstract: A Facile Synthesis of 4,6,7,8,8a,9‐Hexahydropyrrolo[1,2‐a][1,2,3]triazolo[1,5‐d]pyrazines by a Three‐Component Coupling Reaction Followed by Intramolecular 1,3‐Dipolar Cycloaddition.
Authors: Dhondge Attrimuni P. , Afraj Shakil N. , Nuzlia Cut , Chen Chinpiao , Lee Gene‐Hsian
Published: November 2013

Compounds (IV) and (VII) are generally isolated in < 89% d.e.
ChemInform Abstract: The Syntheses, Molecular Structures, Spectroscopic Properties (IR, Micro‐Raman, NMR and UV—vis) and DFT Calculations of Antioxidant 3‐Alkyl‐4‐ [3‐methoxy‐4‐(4‐methylbenzoxy)benzylidenamino] ‐4,5‐dihydro‐1H‐1,2,4‐triazol‐5‐one Molecules.
Authors: Goekce Halil , Bahceli Semiha , Akyildirim Onur , Yuesek Haydar , Kol Oezlem Guersoy
Published: November 2013

The title new compounds are screened for their in vitro antioxidant activity and demonstrated a marked capacity for iron binding.
ChemInform Abstract: Synthesis of Substituted 3‐Iodocoumarins and 3‐Iodobutenolides via Electrophilic Iodocyclization of Ethoxyalkyne Diols.
Authors: Reddy Maddi Sridhar , Thirupathi Nuligonda , Babu Madala Hari , Puri Surendra
Published: November 2013

The new method to synthesize various iodocoumarins and iodobutenolides proceeds via an exclusive 6‐endo‐dig iodocyclization of 3‐ethoxy‐1‐(2‐alkoxyphenyl)‐2‐yn‐1‐ols and 5‐endo‐dig iodocyclization of 1‐alkoxy‐4‐ethoxy‐3‐yn‐1,2‐diols, respectively.
ChemInform Abstract: Organocatalyzed Michael—Michael Cascade Reaction: Asymmetric Synthesis of Polysubstituted Chromans.
Authors: Jia Zhen‐Xin , Luo Yong‐Chun , Cheng Xi‐Na , Xu Peng‐Fei , Gu Yu‐Cheng
Published: November 2013

The title reaction provides a mild and efficient approach for the synthesis of the chiral benzopyrans (III) and (VI) with three consecutive stereocenters.
ChemInform Abstract: Palladium(II)‐Catalyzed Dehydrogenative Cross‐Coupling Between Two Csp3—Bonds: Unexpected C=C Bond Formation.
Authors: Li Gaocan , Qian Shengyou , Wang Chunxia , You Jingsong
Published: November 2013

This is the first method for the construction of C=C double bonds via palladium‐catalyzed oxidative cross‐coupling between two Csp3—H bonds without the need for an extra oxidant.
ChemInform Abstract: Rhodium(III)‐Catalyzed Oxidative Olefination of Pyridines and Quinolines: Multigram‐Scale Synthesis of Naphthyridinones.
Authors: Zhou Jun , Li Bo , Hu Fang , Shi Bing‐Feng
Published: November 2013

Several further synthetic transformations of the primary reaction products are demonstrated, including strategies for the synthesis of some biologically active compounds.
ChemInform Abstract: A Highly Diastereo‐ and Enantioselective Synthesis of Tetrahydroquinolines: Quaternary Stereogenic Center Inversion and Functionalization.
Authors: Luo Chaosheng , Huang Yong
Published: November 2013

A variety of tetrahydroquinolines is prepared with high dia‐ and enantioselectivities using one or two different anilines.
ChemInform Abstract: Heteroatom‐Guided, Palladium‐Catalyzed Regioselective C—H Functionalization in the Synthesis of 3‐Arylquinolines.
Authors: Tiwari Virendra Kumar , Pawar Govind Goroba , Das Riki , Adhikary Amit , Kapur Manmohan
Published: November 2013

A new approach for the regioselective functionalization of the C‐3‐position of quinolines is described.
ChemInform Abstract: Photocycloadditions of Substituted Oxazoles with Isoquinoline‐1,3,4‐trione—Chemo‐, Regio‐, Diastereoselectivities and Transformation of the Photocycloadducts.
Authors: Huang Cheng‐mei , Jiang Heng , Wang Ru‐zhi , Quah Ching Kheng , Fun Hoong‐Kun , Zhang Yan
Published: November 2013

Different from other α‐diketones, photocycloadditions of trione (I) with oxazoles (II) proceed exclusively via a [2 + 2] pathway with exclusive involvement of the C(4) carbonyl group.
ChemInform Abstract: Cascade Electrophilic Iodocyclization: Efficient Preparation of 4‐Iodomethyl Substituted Tetrahydro‐β‐carbolines and Formal Synthesis of Oxopropaline G.
Authors: Song Hongjian , Liu Yongxian , Wang Qingmin
Published: November 2013

4‐Iodomethyl substituted tetrahydro‐β‐carbolines, the core structure of numerous natural products and bioactive molecules, are readily prepared via I2‐promoted cascade electrophilic cyclization.
ChemInform Abstract: Tetrahydroquinolines and Benzazepines Through Catalytic Diastereoselective Formal [4 + 2]‐Cycloaddition Reactions Between Donor—Acceptor Cyclopropenes and Imines.
Authors: Truong Phong M. , Mandler Michael D. , Zavalij Peter Y. , Doyle Michael P.
Published: November 2013

Regio‐ and diastereoselective Lewis acid catalyzed cycloaddition reactions between imines and donor—acceptor cyclopropenes generated from silyl‐protected enoldiazoacetates (I) provide direct access to stable cyclopropane‐fused tetrahydroquinolines and, with cyclopropane ring opening under mild conditions, to 1H‐benzazepine derivatives (IX).
ChemInform Abstract: Protecting‐Group‐Free Total Synthesis of (—)‐Rhazinilam (VII) and (—)‐Rhazinicine (VIII) Using a Gold‐Catalyzed Cascade Cyclization.
Authors: Sugimoto Kenji , Toyohima Kazuki , Nonaka Shiori , Kotaki Kenta , Ueda Hirofumi , Tokuyama Hidetoshi
Published: November 2013

For the first time the asymmetric total synthesis of the title compound (VII) is presented.
ChemInform Abstract: Asymmetric Ruthenium‐Catalyzed Hydrogenation of 2‐ and 2,9‐Substituted 1,10‐Phenanthrolines.
Authors: Wang Tianli , Chen Fei , Qin Jie , He Yan‐Mei , Fan Qing‐Hua
Published: November 2013

The first highly enantio‐ and diastereoselective hydrogenation of 2,9‐ and 1,10‐phenanthrolines using a chiral cationic ruthenium diamine catalyst is presented.
ChemInform Abstract: Cascade Synthesis of Azoquinazolinones by Cu(I)‐Catalyzed C—N Coupling/C—H Activation/C—N Formation Reactions under O2.
Authors: Chen Dingben , Chen Qiufang , Liu Miaochang , Dai Shuangqun , Huang Ling , Yang Jianguo , Bao Weiliang
Published: November 2013

A convenient one‐pot protocol is presented for the reaction of 2‐iodo‐benzamides with various N‐heterocycles to give azoquinazolinone derivatives via the title process.
ChemInform Abstract: Bifunctionalized Allenes. Part 9. An Efficient Method for Regioselective Synthesis of 4‐Heteroatom‐Functionalized Allenecarboxylates.
Authors: Ivanov Ivaylo K. , Parushev Ivaylo D. , Christov Valerij Ch.
Published: November 2013

This reaction proceeds via an atom economical [2,3]‐sigmatropic rearrangement of 2‐heteroatom‐functionalized alk‐3‐ynecarboxylates.
ChemInform Abstract: Hydroxyphosphinylation Reaction of 3‐Cyclopropylideneprop‐2‐en‐1‐ones via C—P σ‐Bond Cleavage.
Authors: Miao Maozhong , Cao Jian , Huang Xian , Wu Luling
Published: November 2013

An unexpected hydroxyphosphinylation of 3‐cyclopropylideneprop‐2‐en‐1‐ones with phosphines is reported providing a unique regio‐ and stereoselective synthesis of highly functionalized (Z)‐alkenyl cyclopropanols with important potential.
ChemInform Abstract: Rhodium(III)‐Catalyzed Oxidative Coupling Through C—H Bond Cleavage Directed by Phosphinoxy Groups.
Authors: Unoh Yuto , Hashimoto Yuto , Takeda Daisuke , Hirano Koji , Satoh Tetsuya , Miura Masahiro
Published: November 2013

A straightforward synthesis of phosphaisocoumarins is achieved by the rhodium‐catalyzed oxidative coupling of diarylphosphinic and phenylphosphonic acid derivatives with alkynes.
ChemInform Abstract: Hydrophosphinylation of Unactivated Terminal Alkenes Catalyzed by Nickel Chloride.
Authors: Ortial Stephanie , Fisher Henry C. , Montchamp Jean‐Luc
Published: November 2013

The simple presented method uses a cheaper catalyst and proceeds for a broad scope of unactivated terminal olefins at room temperature.
ChemInform Abstract: Salimyxins and Enhygrolides: Antibiotic, Sponge‐Related Metabolites from the Obligate Marine Myxobacterium Enhygromyxa salina.
Authors: Felder Stephen , Kehraus Stefan , Neu Edith , Bierbaum Gabriele , Schaeberle Till F. , Koenig Gabriele M.
Published: November 2013

Salimyxin A (I), salimyxin B (II), enhygrolide A (III), and enhygrolide B (IV) are isolated.
ChemInform Abstract: Current Status and Future Developments in Preparation and Application of Colloidal Crystals
Authors: Cong Hailin , Yu Bing , Tang Jianguo , Li Zejing , Liu Xuesong
Published: November 2013

Review: 407 refs.
ChemInform Abstract: 25th Anniversary Article: Understanding the Lithiation of Silicon and Other Alloying Anodes for Lithium‐Ion Batteries
Authors: McDowell Matthew T. , Lee Seok Woo , Nix William D. , Cui Yi
Published: November 2013

Review: 145 refs.
ChemInform Abstract: Ligand Effects on Bonding and Ion Pairing in Cationic Gold(I) Catalysts Bearing Unsaturated Hydrocarbons
Authors: Zuccaccia Daniele , Belpassi Leonardo , Macchioni Alceo , Tarantelli Francesco
Published: November 2013

Review: < 60 refs.
ChemInform Abstract: Synthesis of Transition‐Metal Steroid Derivatives
Authors: Le Bideau Franck , Dagorne Samuel
Published: November 2013

Review: 367 refs.
ChemInform Abstract: Mixed AggregAte (MAA): A Single Concept for All Dipolar Organometallic Aggregates. 2. Syntheses and Reactivities of Homo/HeteroMAAs
Authors: Mongin Florence , Harrison‐Marchand Anne
Published: November 2013

Review: 1708 refs.
ChemInform Abstract: Double Metal‐ligand Exchange in Solvate Complex‐metal Porphyrin Systems
Authors: Berezin B. D. , Zvezdina S. V. , Berezin M. B.
Published: November 2013

Review: 39 refs.
ChemInform Abstract: N‐Heterocyclic Carbene (NHC)—Copper‐Catalyzed Transformations of Carbon Dioxide
Authors: Zhang Liang , Hou Zhaomin
Published: November 2013

Review: 70 refs.
ChemInform Abstract: Recent Advances in the Willgerodt—Kindler Reaction
Authors: Priebbenow Daniel L. , Bolm Carsten
Published: November 2013

Review: 95 refs.
ChemInform Abstract: Sulfonic Acid Functionalized Ordered Mesoporous Materials as Catalysts for Fine Chemical Synthesis
Authors: El Kadib Abdelkrim , Finiels Annie , Brunel Daniel
Published: November 2013

Review: 35 refs.
ChemInform Abstract: Iron‐Catalyzed Alkene Hydroboration with Pinacolborane
Authors: Zhang Lei , Huang Zheng
Published: November 2013

Review: 15 refs.
ChemInform Abstract: Constructing Molecular Complexity from Alkynol Derivatives: A Journey from Fischer Carbene Complexes to Tandem Catalysis with Gold and Other Carbophilic Lewis Acids
Authors: Rodriguez Felix , Fananas Francisco J.
Published: November 2013

Review: 30 refs.
ChemInform Abstract: (—)‐Isosteviol as a Versatile Ex‐Chiral‐Pool Bulding Block for Organic Chemistry
Authors: Lohoelter Christina , Weckbecker Magdalena , Waldvogel Siegfried R.
Published: November 2013

Review: 82 refs.
ChemInform Abstract: Metalated Indoles, Indazoles, Benzimidazoles, and Azaindoles and Their Synthetic Application
Authors: Ila Hiriyakkanavar , Markiewicz John T. , Malakhov Vladimir , Knochel Paul
Published: November 2013

Review: 149 refs.
ChemInform Abstract: Stereocontrolled Total Synthesis of Tetrodotoxin from Myo‐inositol and D‐Glucose by Three Routes: Aspects for Constructing Complex Multi‐functionalized Cyclitols with Branched‐chain Structures
Authors: Sato Ken‐ichi , Akai Shoji , Yoshimura Juji
Published: November 2013

Review: 107 refs.
ChemInform Abstract: Diels—Alder Reactions of 12‐Hydroxy‐9(10→20)‐5aH‐abeo‐abieta‐ 1(10),8(9),12(13)‐triene‐11,14‐dione
Authors: Majetich George , Zhang Yong , Tian Xinrong , Zou Ge , Li Yang , Wang Yangyang , Hu Shougang , Huddleston Eric
Published: November 2013

Review: 102 refs.
ChemInform Abstract: Novel Investigation of 1,5‐Diamino‐4‐methyltetrazolium Perchlorate [C2H7N6]+ [ClO4]‐: A Prospective Challenge to Nitrogen‐rich Ionic Salts and Health Risk
Authors: Swain Pravat K.
Published: November 2013

Review: synthesis, structural aspects, spectroscopic studies, and physico‐chemical properties of the title perchlorate; 43 refs.
ChemInform Abstract: Racemization of Amines and Related Derivatives Leading to Their Dynamic Kinetic Resolution
Authors: Jiang Cheng‐jun , Cheng Gui‐lin
Published: November 2013

Review: 58 refs.
ChemInform Abstract: Recent Contributions from the Asymmetric Aza‐Michael Reaction to Alkaloids Total Synthesis
Authors: Amara Zacharias , Caron Joachim , Joseph Delphine
Published: November 2013

Review: 61 refs.
ChemInform Abstract: Synthesis of Allocolchicinoids. A 50 Year Journey
Authors: Sitnikov N. S. , Fedorov A. Yu.
Published: November 2013

Review: 145 refs.