bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on Relationship of Serum Total Cholesterol Low Density Lipoprotein and Triglycerides With Body Mass Index
Authors: Hossain Kamal , Hoque Mahmudul , Faiz Saifur Nahar , Alam ASM Towhidul
Published: December 2021

The present case control study was designed to determined the relationship between serum Total cholesterol, Low Density Lipoprotein (LDL), Triglycerides (TG) and Body Mass Index (BMI). The study was carried out in the Department of Biochemistry Chittagong Medical College during the period of January 2010- December 2010. Samples were collected from population of different area of Chittagong City Corporation of different occupations, age from 35- 60 years. The data were collected by a structured questionaries which includes age, sex, occupation, dietary habits, family history of hyperlipidemia and DM. BMI was calculated by standardized protocol. Population suffering from DM, renal diseases and other endocrine disease were excluded. A total of 105 subjects were included in this study. Among them 70 were considered as case ( whose BMI was 25 kg/m2) and 35 were considered as control ( whose BMI was < 25 Kg/ m2).Serum Total cholesterol, LDL-C, HDL-C and TG were measured in all samples in fasting state. Study showed that female were more obese than male,( 31.14 +2.23kg/m2 Vs 29.71 +2.69kg/mo), p= <0.05.Results showed that Serum TC(45%), LDL-C(65%), TG(70%) were significantly higher in cases than that of controls (p=<0.001).Serum HDL-C(35%) was significantly decreased in cases than that of controls (p=<0.001).Study showed that hypertriglyceridemia (70%) was the common lipid abnormality and then LDL-C (65%). Study revealed that there was no significant difference in lipid profile between male and female. Pearson's Correlation Coefficient showed that there were positive correlation between TC (r=0.234,p=<0.05), LDL-C (r=0.258,p=<0.01), TG (r=0.409,p=<0.001) and BMI, and was negative correlation between HDL-C(r= -0.403, p= <0.001) and BMI. So early detection and prevention of obesity and abnormal lipid profile can largely reduce morbidity and mortality and alleviate undue burden on our limited health budget.

JCMCTA 2012 ; 23 (2): 22-26
A Study of Liver Function Tests in Patients Receiving Four Drugs Regimen in Initial Two Months as Antitubercular Drugs
Authors: Faiz Saifun Nahar , Haque Mahmudul , Hossain Kamal , Alam ASM Towhidul
Published: December 2021

Biochemical monitoring of liver function is essential because Anti Tubercular Therapy (ATT) induced hepatotoxicity can cause permanent injury to liver and death. This cross-sectional comparative study was conducted in department of Biochemistry of Chittagong Medical College during the period of July 2009- Jun 2010 to determine the association of Anti-TB treatment to alter the liver function in patients of intensive phase of tuberculosis taking Four Fixed Dose Combination of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol. A total of 100 subjects were enrolled in this study. They were divided into two groups. Group A (case) was diagnosed case of tuberculosis and had taken anti TB drugs (four Fixed dose combination) at least for fifteen days and group B (control) was consisting of normal subjects. Serum ALT, AST, Bilirubin and prothrombin time were measured. It was found, that out of 70 subjects 20% had increased level of serum ALT, 17.1% had increased level of serum AST, 20% had increased level of serum bilirubin and only 2.9% had increased level of prothrombin time in case group. Finally, determination of liver functions in patients receiving Anti TB therapy (in intensive phase) should be done irrespective of presence or absence of established risk factors, to minimize not only the incidence but also the morbidity and mortality.

JCMCTA 2012 ; 23 (2): 27-29
One Year Review of Maternal Mortality Associated With Eclamsia in a Tertiary Care Level Hospital
Authors: Siddiqual Shamima , Alam Md Mahbub , Khatun Mahbub Ara
Published: December 2021

To enlist the causes of maternal death in patients of eclampsia and to determine how sociodemograpphic and clinical characteristics of the women influence the death in eclampsia in our setup. This study was conducted in obstetrics and gynaecology department of Chittagong Medical College Hospital, Chittagong, from January 2011 to December 2011. Patients were admitted through emergency obstetrics care unit. Patients demographic record including age, parity, education, socio-economic status along with antenatal care records, level of care and distance from hospital number of fits, gestational age, type of eclampsia, presence of complications, mode of delivery and causes of death were analyzed. All this information was collected from patients records. Eclampsia accounted for 38 (37.7%) of the 101 total maternal deaths recorded within the 1 year period, with case fatality of 9.9%.All patients were unbooked and majority were primigridia(63%) and less than 20 years(39%). Education and socioeconomic status were poor. Ante partum eclampsia was the cause in 78.9% and 5.2% of the pregnancies were not delivered before their death. Overall 23% patients had at least one complications and the remaining 67% had more than one complications. The complications leading to eventual death were pulmonary oedema 7(18.4%), LVF 6(15.7%), CVD 6(15.7%), Multiorgan failure 6(15.7%), HELLP 4(10.5%), DIC 3(7.8%), Renal failure 3(7.8%), peroperative cardiac arrest 2(5.2%) and pulmonary embolism 1(2.6%). The distance from the hospital was 10km to 150km. The level of care at nearest health facilities were estimated.52.6% was attended by traditional birth attendant, 6.9% by skilled birth attendants, 2.9% by doctors and for 25.7%, no level of care was available. Eclampsia stil remains the major cause of maternal mortality in our setup resulting from unsupervised pregnancies and deliveries. There is need to educate and encourage the general public for antenatal care and hospital delivery.

JCMCTA 2012 ; 23 (2): 30-33
Clinical Laboratory and Pathological Features Of Admitted Lupus Nephritis Patients
Authors: Duttal Pradip Kumar , Chowdhury Pratik , Haider Md Shafiul , Roy Satyajit , Faruk Md Golam , Kashem Md Abul , Huda Md Nurul , Das Saibal , Paul Sujat , Dutta Arup
Published: December 2021

Clinical features of Systemic Lupus Erythematosus (SLE) worsens when it involves kidneys. Even then in our socioeconomic context the patients who seek admission are usually at later stages. Moreover histological classes may not be previewed by clinical and laboratory features. The aim of the study is to show variation of clinical features and laboratory findings in relation to pathological classes of Lupus nephritis. It was a cross sectional descriptive study enrolling 30 female patients admitted in medicine and nephrology department of Chittagong Medical College. Majority of the patients are of age range 21-40 years (73%); belonging to middle class family (90%) and educated upto level of secondary school certificate (43%). Oedema (93%), normotension (73%) and anaemia (93%) are common clinical features. Though all patients had macroscopic proteinuria only 20 % patients had massive proteinuria (>3gm%). Serologically Nineteen patients are ANA positive (63%) and all patients had Anti-dsDNA positivity. Class III and Class IV comprises 70% of patients. Estimated Glomerular filtration rate (eGFR) is more in class V ( mean 77.77) and class III (mean 76.86) than class II ( mean 52.67) and class IV ( mean 59.95) signifying eGFR cannot estimate severity. In conclusion without renal biopsy Lupus nephritis class cannot be ascertained and so class specific management cannot be given.

JCMCTA 2012 ; 23 (2): 34-37
Anthropometric Parameters of Newborn Infants
Authors: Das Jagadish C
Published: December 2021

Bangladesh is a densely populated developing country. Majority of the population live here in the rural community. Illiteracy, poverty and malnutrition are widely prevalent here. Health service facilities even for the neonate are not satisfactory. Anthropometric parameters at birth are considered to be of great value. Incidence of low birth weight is high in our area. Though study on anthropometric parameters on neonate in our country had been undertaken in the past, attempt on various anthropometric parameters at a time are not much. Here, an attempt has been taken to study maximum anthropometric parameters on neonates at a time so that an idea can get on these parameters. It was a descriptive cross-sectional study on 560 newborn infants over a period of one year six months. In this work, mean gestational age of neonate was 37.9±10 week. Mean birth weight was 2507 580 gm but mean birth weight of term neonates were 2770 gm. Approximately 47% babies were low-birth weight. Though observed mean birth length was 48.1 = 3.1cm, the average length for term babies was 49.4±1.8 cm. Values of observed mean mid-arm circumference, head circumference, chest circumference, abdominal girth and calf circumference were 9±1.3 cm, 32.8±2.0 cm, 30.2±2.9 cm, 27.7±2.6 cm and 10.11.2 cm respectively. All anthropometric parameters were marginally more in male than in female babies.

JCMCTA 2012 ; 23 (2): 38-41
Unusual and Late Recurrence in Ovarian Adult Granulosa Cell Tumour: A Case Report
Authors: Noor Serajun , Ahmed Jashim Uddin , Chowdhury Shahanara , Rahman Zillur
Published: December 2021

Granulosa cell tumour of ovary are rare hormonally active neoplasm characterized by indolent course, local spread with a preponderance for extremely late recurrence and high survival rate. We report a 60 year old lady presented in 2009 with aggressive looking growth in vulva 16 years after her total abdominal hysterectomy with Bilateral salphingo-ophorectomy with infracolic omentectomy for suspected stage granulosa cell tumour of ovary , confirmed by histopathology. She remained disease free for 13 years and in 2005 underwent resection of retroperitoneal mass with multiple peritoneal implant, confirmed to be a granulosa cell tumour after biopsy. Despite six course adjuvent combination therapy with complete response she presented after 4 years in 2009 with a second recurrence in vulva. She had tumour reductive surgery followed by chemotherapy and hormonal therapy but the disease was progressive. In conclusion late recurrence and repeat recurrence is a hallmark for granulosa cell tumour of ovary, so we emphasis the need for long term follow up and consider the possibility of recurrence when presented with acute abdomen after initial surgery for granulose cell tumour. But there is no standard management protocol and we review this patients treatment in the context of current literature.

JCMCTA 2012 ; 23 (2): 42-46
Intravesical Foreign Body: A Case Report
Authors: Ul Haque Mohammed Monowar , Md Nizamuddin -
Published: December 2021

Foreign body in the urinary bladder is not very common. It may occur by self insertion or migration from neighboring organs. It represents a urologic challenge which requires prompt management and should be treated as emergencies. Most of the foreign bodies in the urinary bladder can be successfully removed endoscopically. Sometimes open surgical procedure may require in removing the foreign body. Removal of foreign body from urinary bladder may be quite challenging requiring imaginations & high level surgical skills. Here we reported a case of 29 years old mentally retarded man with an intravesical foreign body. We successfully removed the foreign body by endoscopic procedure under general anesthesia. In post operative follow up there was no voiding problem & patient was advised for psychiatric consultation.

JCMCTA 2012 ; 23 (2): 47-49
Uterine Perforation With Bowel Infarction In a Case of Unsafe Abortion
Authors: Ferdous Afroza , Chowdhury Shahanara , Akter Rawshan
Published: December 2021

Every year worldwide about 42 million women with unintended pregnancies choose abortion, and nearly half of these procedures, 19 million, are unsafe. Some 70,000 women die of unsafe abortion annually, making it one of the leading causes of maternal mortality (13%). Of the women who survive unsafe abortion, 5 million will suffer longterm health complications. Unsafe abortion is thus a pressing issue. Both of the primary methods for preventing unsafe abortionless restrictive abortion laws and greater contraceptive useface social, religious, and political obstacles, particularly in developing countries, where most unsafe abortions (97%) occur. Even where these obstacles are overcome, women and health care providers need to be educated about contraception and the availability of legal and safe abortion, and women need better access to safe abortion and post abortion services. Otherwise, desperate women, facing the financial burdens and social stigma of unintended pregnancy and believing they have no other option, will continue to risk their lives by undergoing unsafe abortions. According to the World Health Organization (WHO), every 8 minutes a woman in a developing nation die of complications arising from an unsafe abortion. The fifth United Nations Millennium Development Goal recommends a 75% reduction in maternal mortality by 2015. WHO deems unsafe abortion one of the easiest preventable causes of maternal mortality and a staggering public health issue. We report a case of a 21 years female who presented with uterine perforation with small intestinal prolapse through uterine perforation that required repair of uterine perforation with resection anstomosis of small gut after a unsafe abortion of a 16 weeks pregnancy.

JCMCTA 2012 ; 23 (2): 50-52
Comparison Between Preoperative Image Guided Biopsy and Open Biopsy in Clinically Labeled “Unresectable Carcinoma Pancreas”
Authors: Al Farooq Md Abdullah , Bhuiyan Md Akbar Husain , Tajreen Tania , Ali Mohammad
Published: December 2021

Although clinical findings along with modern laboratory investigations and imaging can help to diagnose pancreatic cancer and label them respectable or unrespectable, tissue diagnosis is essential to confirm the diagnosis and proper management. This retrospective review was done form July 2004 to June 2006 in BIRDEM hospital, Dhaka, Bangladesh, in patient with clinically labeled 'unresectable carcinoma pancreas' to evaluate the preoperative and postoperative biopsy pattern with their histopathological diagnosis. Forty (40) patients were clinically labeled as ‘unresectable carcinoma pancreas'. Preoperative image guided biopsy was taken in 25 patients. Methods of preoperative tissue diagnosis with their histopathology reports were noted. In forty (40) patients it was planned to take open biopsy along with other palliative surgical procedures. In 38 patients tumours found unresectable and biopsy were taken from the lesion, involved organ or lymph node. In 2 patients curative resection were done and whole specimens were sent for histopathology. Histopathology report of post surgical specimen was compared with preoperative histopathology report. Preoperative biopsies were done by ERCP in 12 patients. Ten (10) image (ultrasonography, computed tomography scan) assisted fine needle aspiration biopsy were taken from the pancreatic lesion. Preoperative imaging failed to detect any pancreatic mass in the rest 3 patients but showed suspected liver metastasis. Image (computed tomography scan) assisted 03 fine needle aspiration biopsies were taken from 3 hepatic metastasis. Histopathological report showed pancreatic duct cell carcinoma in 19 (76%) patients, 1(4%) patients had chronic pancreatitis. Biopsy report was not conclusive in 2 (8%) patients. All 3 biopsies from liver focus were metastatic pancreatic cancer (12%). Histopathology report of laparotomy samples revealed that 35 patients (87.5%) had pancreatic duct cell carcinoma. Out of the rest 5 patients 2 patients (5%) were chronic pancreatitis, non Hodgkin's lymphoma 01 patients (2.5%), tuberculosis 01patients (2.5%) and metastatic renal cell carcinoma 01 patient (2.5%). Open biopsy has a greater diagnostic accuracy than preoperative biopsy in diagnosing unrespectable pancreatic carcinoma and to exclude other pancreatic mass lesions labeled clinically as ‘unrespectable carcinoma pancreas'. Open biopsy is recommended in clinically labeled 'unrespectable carcinoma pancreas'.

JCMCTA 2012 ; 23 (2): 53-57
Gastrocnemius Muscle Flap for Coverage Of Knee & Proximal Third of Tibial Defects
Authors: Biswas Alak Kanti , Kabir Tafhim Ehsan , Chowdhury M Nazrul Islam , Hye Md Abdul , Matin Quasarul , Das Chandan Kumar
Published: December 2021

Gastrocnemius is the muscle of choice for reconstruction of defects involving soft tissue loss over the upper third tibia as well as knee joint. We present a series of 12 patients who underwent gastrocnemius muscle flap(Medial head, proximally based) coverage for this type of defects. Patients age-18 years or above. There were 9 males and 3 females. In all cases, delayed reconstruction was performed ranging from 1 week to 3 months after the creation of defects. Maximum number of pts were within 18-35 years age groups (66.66%), 75% were victims of RTA, 75% had associated fractures. Results of surgery were graded as excellent(83.33%) to good(16.67%) depending upon the outcome and functional restoration of patients. There was no case of complete muscle flap failure. Minor complications were ( 1 pt. developed partial flap necrosis & 1 pt. developed infection) noted but none required a separate operative procedure. We have found this procedure to be reliable, technically easy, biologically sound and esthetically acceptable.

JCMCTA 2012 ; 23 (2): 58-61
Probiotics and Prebiotics
Authors: Dutta Pradip Kumar , Dutta Arup , Islam Md Nazrul , Chowdhury Pranab Kumar , Ghose Sankar Kumar
Published: December 2021

Thousands of species of bacteria colonize gut. The number of microbes is ten times that of total human body cells. The intestinal microbiota is not always harmful, sometimes it is beneficial for human health. If the growth and activity of the intestinal microbiota is perturbed, it may lead to various diseases such as irritable bowel syndrome, autoimmune diseases, infections, colon cancers, gastric ulcers, cardiovascular disease and obesity. Restoration of the gut microbiota may be done by the use of probiotics (beneficial bacteria). Prebiotics, on the other hand, are the food substrate for probiotics. This review article describes uses and harms of probiotics and prebiotics in the body and their rationale for using in diet.
JCMCTA 2012 ; 23 (2): 62-68
Prevention of inflammatory complications in treatment of patients with acute odontogenic purulent periostitis of the jaws
Authors:   National University of Health of Ukraine named after P.L. Shupyka, Kyiv, Ukraine, Tymofieiev O. , Maksymcha S. ,   Kyiv Medical University, Kyiv, Ukraine, Yarifa M. ,   Kyiv Medical University, Kyiv, Ukraine, Dubichenko S. ,   Kyiv Medical University, Kyiv, Ukraine, Myroshnyk A. ,   Kyiv Medical University, Kyiv, Ukraine, Savitskiy O. ,   Kyiv Medical University, Kyiv, Ukraine, Blinova V. ,   Kyiv Medical University, Kyiv, Ukraine, Ucharska O. ,   Kyiv Medical University, Kyiv, Ukraine, Serga O. ,   Kyiv Medical University, Kyiv, Ukraine
Published: December 2021

Purpose: to determine the effectiveness of the drug «Tantum Verde®» for the prevention of inflammatory complications in the oral cavity and peri-maxillary soft tissues in patients with acute odontogenic purulent periostitis of the jaws. Methods: 118 patients with acute odontogenic purulent periostitis of the jaws aged from 16 to 65 years were examined (86 people – the main group, 32 people – the control group). Results: on the basis of examinations those patients with acute odontogenic purulent periostitis of the jaws it was found that the drug «Tantum Verde®» used for oral baths after opening subperiostal abscesses has a pronounced antiseptic, anti-inflammatory, analgesic and deodorizing effects. Conclusions: using the drug «Tantum Verde®» made it possible to reduce the number of pyoinflammatory complications and reduce the duration of treatment of patients. During the research was established that the drug «Tantum Verde®» is an effective antimicrobial, analgesic, anti-inflammatory and antipyretic drug and can be recommended for the treatment of patients with acute odontogenic purulent periostitis of the jaws. Key words: pain, inflammation, complications, immunity, periostitis, Tantum Verde®.
Genetic and epigenetic factors of caries
Authors:   Uzhhorod National University, Uzhhorod, Ukraine, Bilynskyi O. , Kostenko Ye. ,   Uzhhorod National University, Uzhhorod, Ukraine
Published: December 2021

Summary. The paper analyzes the literature on the causes of caries, including the most common epigenetic factors, such as poor oral hygiene, adequate or deficient nutrition, the nature of food, biogeochemical and territorial factors, the content of microelements of water and soil, the level of environmental pollution, etc., as well as considering the genetic component, type of blood group, the structure of the hard tissues of the tooth, including a set of genes responsible for the occurrence and development of carious pathology. It was found that in conditions of fluoride and iodine deficiency, environmental factors have a critical role in the formation of the population-characteristic pattern of changes in dental status associated with the prevalence and intensity of caries. However, variations in these indicators may be partly mediated by the influence of genetically associated factors. The results of the analysis allowed to identify opportunities for the formulation of several independent analytical approaches that would help establish the significance of the genetic component in the structure of caries prognosis in terms of interaction with environmental conditions, actually determining how certain environmental factors can influence changes in genetic predisposition to caries. It can be summarized, that all currently available studies of the role of heredity in the risk structure of caries pathology is divided into two broad categories: identification of specific localized changes in genotype and verification of combinations or sets of such changes that can determine caries risk. Key words: caries, caries intensity, caries prevalence, genetics, twins, epigenetics, environment, saliva pH.
The use of adhesive fiber systems for restoring dental defects
Authors:   National Medical University. O.O. Bogomolets, Kyiv, Ukraine, Kolenko Yu. , Litvin T. ,   JenDental-Ukraine Company, Kyiv, Ukraine
Published: December 2021

Summary. The article deals with the use of adhesive fiber systems for the restoration of dentition defects. Adhesive bridges made in a direct way in one patient visit allow for the restoration of single included defects in the dentition with minimal preparation of abutment teeth. Key words: included dentition defects, adhesive bridges, fiber reinforcement elements; composite materials.
Type 3 Dens Invagination. Diagnosis and comprehensive treatment
Authors:   Dentis Empire LLC, Kyiv, Ukraine, Degasyuk V.
Published: December 2021

Object: researching the combination of endodontic and surgical treatment of a tooth with developing dens invaginatus pathology. Materials and methods. X-ray diagnostics were performed with the Veraview X800 Morita. Irrigation with sodium hypochlorite solution 5.25 % with additional ultrasound treatmentabd 17 % EDTA solution were used for drug treatment of invagination and the main channel. The root canal and invagination, due to a non-standard structure, were handled by VDW hand tools combined with the Aurum BLUE (Meta Biomed) machine tool. Constant obturation was performed by the method of vertical compaction «Siller-AN plus». During the surgical stage, Langer (Hu-Friedy) periodontal curettes, CL 8 (Hu-Friedy) curettage spoon, 141-004-31W Oval Spoon Excavator (Hu-Friedy) were used; access to the focus was formed using a piezo surgical spherical nozzle (CE 1, Piezotome Solo (Satelec, Akteon). 4583 Kohler needle holder was used for suturing, suture material – polypropylene 5.0. The bone defect was filled with xenogenic material BIO GEN cancellous size 2/3 mm, 2.0 (Biotek), the barrier membrane – BIOCOLLAGEN (Biotek), the periodontal defect was filled with BIO GEN mix (Biotek). Key words: dens invaginatus, tooth in tooth, endodontic treatment, bone augmentation, apical surgery.
Study of physicochemical properties of oral fluid in persons with periodontal disease on the background of metabolic syndrome
Authors:   Bukovynian State Medical University, Chernivtsi, Ukraine, Glushchenko T.
Published: December 2021

Topicality. Over the past few years, scientists have attracted the attention of the problem of studying the relationship between metabolic syndrome and periodontal disease. Topics of risks associated with the association with various metabolic disorders have become one of the most important research topics in periodontology. Oral fluid plays a leading role in the proper functioning and maintenance of homeostasis of the entire periodontal tissue complex, is a mediator of the combination of its structures with the environment and an important nutrient substrate for the microflora of the oral cavity. The aim of the study. In order to study the quantitative and qualitative changes of oral fluid in periodontal diseases on the background of the metabolic syndrome, the rate of secretion of mixed saliva, its viscosity and acid-base balance were studied. 2 groups were formed for research: basic and comparative. Materials and methods. The main group included 30 people with inflammatory-dystrophic lesions of the periodontium on the background of metabolic syndrome, the comparison group consisted of 30 people with periodontal disease without endocrinological pathology. Results and discussion. The results of the study revealed homeostatic shifts in the oral biosystem of persons with periodontal disease on the background of metabolic syndrome: a decrease in salivation may indicate a violation of the secretory function of the salivary glands on the background of metabolic disorders, which naturally affected the increase in saliva viscosity. Conclusions. The predominance of acidosis in the oral cavity and the reduction of the protective properties of saliva becomes an important factor in creating a periodontopathogenic situation in the oral cavity and aggravating the course of periodontal disease in this category of patients. Key words: metabolic syndrome, periodontal disease, oral fluid, physicochemical properties.
Six-year analysis of traumatic injuries of the craniomaxillofacial area: relation between maxillofacial and traumatic brain injuries
Authors:   Institute of Postgraduate Education of the National Medical University. O.O. Bogomolets, Kyiv, Ukraine, Shuminsky E. , Kopchak A. ,   Institute of Postgraduate Education of the National Medical University. O.O. Bogomolets, Kyiv, Ukraine
Published: December 2021

Summary. Craniofacial trauma is one of the most difficult types of injuries. There is disagreement among various authors about the relationship between maxillofacial trauma (MFT) and traumatic brain injury (TBI). Purpose. Retrospectively evaluate the epidemiology of traumatic injuries of the craniomaxillofacial area and determine whether there is a relationship between different isolated or combined fractures of the facial bones and brain damage. Materials and methods. The case histories of three groups of patients with isolated fractures of the mandible (I group), isolated fractures of the midface zone (II group) and combined fractures of all areas of the face (III group), who were hospitalized in the period from 2012 to 2017, were analyzed. The main epidemiological indicators were determined. The analysis of indicators of severity of MFT and TBI is carried out. Correlation analysis of indicators, analysis using the Kruskal- Wallis test and Steel-Dwass test for pairwise comparisons was performed. Results. Were treated519 patients. 457 men (88 %) and 62 women (12 %). The main causes of injuries were assaults (40 %). Correlation analysis did not reveal the dependence of MFT and TBI. The difference in severity of isolated fractures of the mandible and midface bones was statistically significant, and there is a statistical significance between the severity of TBI in case of isolated fractures of midface bones and panfacial fractures (p < 0.05). Conclusions. The severity of maxillofacial trauma in the case of panfacial fractures is on average 3 times higher than in the case of isolated fractures of the lower jaw or midface bones. The severity of TBI is largely consistent with concussion in all groups, but in the group with panfacial fractures, the median rate is lower comparing to other groups. Key words: Glasgow coma scale, fracture, Le Fort, traumatic brain injury
The period of the pandemic is the hour of the poke of new possibilities
Authors:   Stamil Dental Research and Clinical Center, Kyiv, Khlyebas S.
Published: December 2021

Summary. With the appearance of bugs of critical situations during the COVID-19 pandemic, it is much more effective than the solution, and it is also often the case that patients are killed on assistance at the advanced stages of protection. Yak for a drug user and for a patient of a bug of factors rizik for an hour of a dental appointment. Medical personnel in the field of individual control, however, it is relevant to feed the fast triviality with the method of reducing the risk of information and increasing the throughput (probing patients) Key words: Futurabond U, ORMOCER®, universal nano-hybrid photopolymer material «Admira Fusion» restoration.
Comparative characteristics of the effect of the drug based on amantadine hydrochloride on changes in the titers of neuromarkers in experimental iatrogenic compression-toxic lesions of the lower alveolar nerve in normoglycemic rabbits and on the background of alloxan diabetes
Authors:   Vinnytsia National Medical University named after E. Pirogov, Vinnytsia, Ukraine, Perlova A. , Shinkaruk-Dikovitskaya M. ,   Vinnytsia National Medical University named after E. Pirogov, Vinnytsia, Ukraine, Kovalchuk L. ,   Vinnytsia National Medical University named after E. Pirogov, Vinnytsia, Ukraine, Kutsak O. ,   Vinnytsia National Medical University named after E. Pirogov, Vinnytsia, Ukraine
Published: December 2021

Resume. Under the conditions of an experimental study of normoglycemic animals and the creation of aloxan sugar diabetes (ASD) as a premorbital background, iatrogenic damage to the lower alveolar nerve by filling materials based on resorcinol-formalin and epoxy resin causes destructive - degenerative changes, as evidenced by an increase in neuromarker titers NSE and S100 protein. After a 30-day therapy with a drug based on amantadine hydrochloride at a dose of 10 mg / kg, both indicators in both study groups significantly decreased. The titers of NSE and S100 protein in the group with ASD in both subgroups were 1.94 times, and 1.87 times less, which indicates the effectiveness of its use in this pathology, but compared with the group of normoglycemic animals, these indicators were 1.1 times and 1.72 times less, which occurred against the background of a parallel decrease in S 100 protein titers by 1.99 and 2.04 times, which indicates the presence of neuroprotective activity in this drug. This, in turn, is conducive to its further clinical research and the involvement of a drug based on amantadine hydrochloride in the main protocol for the treatment of patients with diabetes. Key words: iatrogenic compression-toxic lesion of the lower alveolar nerve, aloxan sugar diabetes, neuron-specific enolase, S 100 protein, amantadne hydrochloride, neuroprotection.
Adhesive photocomposite prosthese – option of restoration of dental row defect in the frontal area (clinical case report)
Authors:   Enigma Beauty Salon, Kyiv, Ukraine, Mochalov I. , Golinka O. ,   Uzhhorod National University, Uzhhorod, Ukraine
Published: December 2021

Summary. Having and maintaining a smile aesthetic is an essential component of modern popular culture. Adhesive bridges («Maryland bridge») have been developed to eliminate single included defects in the dentition in the frontal areas, without preparing the supporting teeth. In modern conditions this technology is the method of choice since single defects in the anterior part of the dentition can also be eliminated through orthodontic treatment, manufacturing of a partially removable plate prosthesis, a traditional dental bridges, the manufacturing of cantilever orthopedic structures and prosthetics based on a dental implant. Adhesive dentures are a relatively new dental technology (which is on the border of orthopedic and therapeutic dentistry) the first work in this direction was carried out in the early 80s of the twentieth century. Modern adhesive bridges are divided into two large groups – solid metal and photopolymer (composite) which prevail in practice. The optimal form of the release of the reinforcing element which combines a slight preparation of abutment teeth to a safe depth, high physical and mechanical properties, simple achievement of the anatomical shape of the teeth in the bridge structures of the anterior and posterior teeth is fiberglass in the form of ribbons 2 mm wide, up to 0.5 mm (this is the most effective width and thickness for clinical practice) and braided type. Using adhesive bridges, it is possible to optimally restore the aesthetics of the anterior part of the dentition in one visit without preliminary preparation of adjacent teeth. An example of the manufacture of a photocomposite adhesive prosthesis reinforced with glass fiber for the restoration of a single included defect in the dentition in the frontal area using domestically produced materials is given. Key words: teeth, defect, composite, adhesion, fiberglass.
The influence of periodont tissue diseases on the quality of life of patients
Authors:   National Medical University. O.O. Bogomolets, Kyiv, Ukraine, Kolenko Yu.G. , Volovyk I.VolovykA. ,   National Medical University. O.O. Bogomolets, Kyiv, Ukraine, Myalkivsky K.O. ,   Smile Quarter Dental Clinic, Kyiv, Ukraine
Published: December 2021

Relevance. One of the most pressing problems in dentistry today is periodontal disease. According to the World Health Organization (WHO), tooth loss from gum disease develops 5 times more often than in caries complications and is the second most common. Periodontal diseases are diagnosed in 85–95 % of the adult population of our country over the age of 35. Goal. Based on clinical data and quality of life of patients to analyze and evaluate the effectiveness of Tantum Verde® in comparison with the traditional scheme. Materials and methods. Examination and comprehensive treatment of 86 young people aged 20 to 45 years (42 men and 44 women), of which 66 were patients with generalized periodontitis initial–I degree, chronic course, and 20 patients with intact periodontium. The 1st (20 patients) group included persons who get traditional periodontal treatment, the 2nd comparison group (46 patients) consisted of participants who additionally received Tantum Verde®. Objective examination of the condition of periodontal tissues was performed using indices: hygienic OHI-S, periodontal PI, papillary-marginal-alveolar PMA. Assessment of the quality of life of patients with generalized periodontitis initial–I degree, chronic course was performed using the questionnaire SF-36, adapted for patients with inflammatory periodontal diseases. Results. As a result of the treatment, positive results were achieved in both groups. Clinically, there was a thickening of the gums, no redness and swelling of the interdental papillae. A significant decrease in periodontal indices was observed in patients of both the 1st and 2nd groups. In a comparative aspect, it was noted that the reduction in OHI-S and PI was effective in all study participants, PMA – more pronounced in those who used Tantum Verde®. Patients of the second group noted an improvement in the clinical condition of periodontal tissues by 89.7 %; physical condition by 86 %; psycho-emotional state by 84.1 %; social function – by 64.7 %; from the block of questions about the peculiarities of the treatment of many patients worried about the fear of future treatment, uncertainty about the effectiveness of therapy and the use of interdental hygiene, indicators in this group decreased by 78.9 %. Conclusion. The assessment of the quality of life of patients showed that the use of Tantum Verde® gives a significant improvement in quality of life, which is manifested in a reduction in the number of exacerbations and increase the duration of remission. Key words: generalized periodontitis, periodontal tissues, quality of life, Tantum Verde®.
Retrospective analysis of the frequency of detection of cystic lesions of the maxillofacial area and neck
Authors:   Vinnytsia National Medical University named after E. Pirogov, Vinnytsia, Ukraine, Krynychnykh H. , Shuvalov S. ,   Vinnytsia National Medical University named after E. Pirogov, Vinnytsia, Ukraine
Published: December 2021

Abstract. The frequency of detection of cystic lesions of the head and neck in dental patients of the maxillofacial department of the Vinnitsya Regional Clinical Hospital named after N.I. Pirogov on the basis of a retrospective analysis of the hospital’s archival materials for five years was determined. The structure of the cysts of the maxillofacial region with the correlation of age and gender indicators is described. Key words: frequency, cyst, retrospective analysis, correlation.
Assessment of the dynamics of x-ray morphometric indices of the jaws in children with variable bite
Authors:   Lviv National Medical University named after Danylo Halytsky, Lviv, Ukraine, Isakova O. , Makeev V. ,   Lviv National Medical University named after Danylo Halytsky, Lviv, Ukraine
Published: December 2021

Purpose: to determine the peculiarities of the dynamics of the roentgenomorphometric indices of the jaws in children during the period of mixed bite. Materials and methods. The study assessed the dynamics of radiological indices (mental index (MI), gonial index (GI), upper and lower panoramic mandibular indices (PMI-S and PMI-i)). The study used orthopantomograms of 107 children (65 boys and 42 girls) aged 6–13 years from Lvov and Lviv region. All children were divided into age groups with the preservation of a proportional and harmonious distribution, both by sex and by age. Results. After evaluating the results of the study, the age periods of active restructuring of the bone structure of the child's jaws were identified. A characteristic feature of variations in index indicators is different age phases of active changes for boys and girls. The only common period for both sexes is the age of 9–10 years, when there is an increase in almost all index indicators, which coincides with the beginning of the eruption of multi-rooted teeth. Conclusions. Evaluation of index indicators using orthopantomograms in children during the period of mixed bite is an important diagnostic criterion for detecting active morphometric changes in the bone structures of the maxillofacial region, as well as an auxiliary diagnostic criterion when planning the timing of dental or orthodontic intervention. Key words: orthopantomogram, radiological indices, mental index, gonial index, upper and lower panoramic mandibular indices.
The instrument transfer method in four handed dentistry in dental operating microscope as a module of a training program in the aspect of reduction of the dynamic load of the visual system of the operator
Authors:   Kyiv International University, Kyiv, Ukraine, Goczewski Maciej , Stupnytsky R. ,   Kyiv International University, Kyiv, Ukraine
Published: December 2021

Resume. Introduction of a Dental Operating Microscope (DOM) in the clinical work can make some difficulties in operator’s work.In particular, to ensure the safety of the operator’s visual system and ergonomics of the work, the operator’s gaze should be continuously directed to the operating field. The instruments should be moved over the operating field by the assisting personnel, whose participation in the transfer is not complete until the evening nstrument is visible through the microscope and the operator is fully capable of controlling its movement. Instrument transfer method in DOM includes 3 steps: modified direct placement, predelivery, delivery and exchange of instruments. In the presented method the most important elements are the properly oriented end of the instrument by dental assistant and mutual grasp of instrument. The method allows to reduce the load on the operator’s visual system and to make four-handed work ergonomic. Key words: dental operating microscope (DOM), four-handed dentistry in DOM, instrument transfer in DOM, mutual grasp, visual system overload of dental operator.
Priority of clinical application of photodynamic therapy using the HELBO Thera Lite laser in the treatment of perodonton tissues in parodonton tissues
Authors:   Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Matviykiv T. , Rozhko M. ,   Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Hereliuk V. ,   Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine
Published: December 2021

Abstract. The availability of a huge number of tools, methods and techniques for the treatment of generalized periodontitis is not always effective in clinical practice, especially during a pandemic over COVID-19. The use of high-tech innovative techniques, including photodynamotherapy with HELBO Thera Lite laser can be a particularly promising area as an adjunct to the comprehensive treatment of generalized periodontitis. The technique is characterized by a decent arsenal of advantages over competitors on the market – is 92 % effective against typical periodontal pathogens, minimally invasive, does not require additional use of pharmaceuticals, including antibiotics, does not cause and is not accompanied by excessive psychological stress, has no side effects on others organs and systems. The relevance of its use in dental practice can significantly improve traditional methods of comprehensive treatment of generalized periodontitis, especially in patients after coronavirus infection, which further requires scientifically proved confirmation by studying the features of clinical, microbiological, biochemical and immunological parameters. Key words: generalized periodontitis, photodynamic therapy, Helbo therapy, coronavirus infection.
Paineet kypsyttävät huippusuorittajan
Authors: Isopahkala-Bouret Ulpukka
Published: December 2021

Julkisuudessa on viime aikoina puhuttanut erityisesti nuorten lukiolaisten ja yliopisto-opiskelijoiden jaksaminen tulevaisuutta koskevien valintojen ja vaatimusten ristipaineissa. Löytyykö oma paikka opintojen jälkeen työelämästä, onko se mieluinen ja mitä se vaatii? Nuoret aikuiset siirtyvät koulutuksesta työelämään vain huomatakseen, että heiltä odotetaan sielläkin yhä uusia näyttöjä ja jatkuvaa uuden opettelua. Olisi hyvä kysyä, millaiset rakenteelliset muutokset rakentavat systeemiä, joka ei palkitse liiallisesta suorittamisesta ja itsensä venyttämisestä äärirajoille. Perustavaa muutosta tarvitaan sekä arvostuksissamme että arvioinnin ja palkitsemisen käytännöissä. Uusi ideaali voisi olla yhteiskunta, jossa omaa arvoaan ei tarvitsisi todistella jatkuvalla itsensä ylittämisellä.
Eritapainen toimijuus koulutusvalinnoissa ja työelämässä
Authors: Vaattovaara Virpi , Ylitapio-Mäntylä Outi
Published: December 2021

Tarkastelemme eri-ikäisten aikuisten koulutusvalintoja ja kokemuksia työelämästä. Pohdimme toimijuuden rakentumista sukupuolitapaisten toistojen tuloksena koulutuksessa ja työelämässä. Sukupuoli ohjaa usein valitsemaan sille merkittyjä koulutusaloja ja työtehtäviä. Kun toimijat ajatellaan samankaltaisiksi sukupuolen määrittämänä, uusinnetaan samalla yhteiskunnassa vallitsevia odotuksia. Erilaisten ja eritapaisten valintojen kautta on kuitenkin mahdollista purkaa tai muuttaa vallitsevia toimijuuksia määritteleviä diskursseja. Ensimmäinen aineistomme sisältää aikuisten kirjoitelmia ja haastatteluja, toinen koostuu varhaiskasvatuksen opettajaopiskelijoiden portfoliokirjoituksista. Luimme aineistoja ristiin toimijuusanalyysiin liittyvien modaliteettien täytyä, voida, tuntea, haluta, kyetä ja osata avulla. Kysymme, 1) millä tavoin sukupuolitapaisuus ohjaa koulutusvalintoja ja työelämän käytäntöjä ja 2) millaisilla modaalisilla ehdoilla valinnat mahdollistavat eritapaisen toimijuuden. Tulosten mukaan ymmärrystä sukupuolitapaisuudesta voidaan laajentaa, ja eritapaisuus voidaan nähdä toimijuuden mahdollisuutena sekä vastarintana odotetuille ja normitetuille valinnoille. Tutkimuksemme osoittaa, että koulutuksen ja työelämän vakiintuneita käytäntöjä kohtaan esiintyy tottelemattomuutta ja epäilyä. Samanaikaisesti tuloksemme paljastavat kahlittuja sukupuolittuneita tiloja, joissa mukaudutaan perinteisiin, diskursiivisiin toimijuuksiin.
Toimijuuden ja identiteetin yksilölliset ja sosiaaliset painotukset korkeakoulutettujen urapoluilla
Authors: Hanhimäki Eija , Vähäsantanen Katja , Rantanen Johanna
Published: December 2021

Tarkastelemme tutkimuksessa toimijuutta ja identiteettiä korkeakoulutettujen uratarinoissa. korkeakoulutettujen urapolkuja tutkimalla tunnistamme sekä korkeakoulutettujen urien rakentumisen tapoja että yksilön ja yhteiskunnan asettamien odotusten ja tavoitteiden merkitystä urapoluilla. Aineisto koostui Töissä.fi-verkkopalvelun kautta kerätyistä korkeakoulutettujen uratarinoista (N = 462). Tutkimusaineiston narratiivisessa analyysissa tarkastelimme, millaisia urapolkuja uratarinoista oli tunnistettavissa sekä millaisia toimijuuden ja identiteetin yksilöllisiä ja sosiaalisia painotuksia uratarinat sisälsivät. Analyysin pohjalta loimme seitsemän uratyyppitarinaa, jotka nimesimme urapolun rakentumista kuvaavalla tavalla. Uratyypit olivat 1) suunnitelmalliset, 2) osaamisen tunnistajat, 3) aktiiviset, 4) sattuman kuljettamat, 5) intohimon ohjaamat, 6) polveilijat ja 7) yrittäjähenkiset. Uratyyppitarinat kuvaavat, kuinka korkeakoulutettujen toimijuus ja identiteetti olivat uratarinoissa eri tavoin yksilöllisesti tai sosiaalisesti painottuneita. Toimijuuden ja identiteetin painottuminen kuvasti sitä, miten yksilöllisesti tai sosiaaliseen yhteisöön nojautuen eri uratyypit tekivät omaa uraa koskevia valintoja sekä määrittivät, mitä he halusivat olla työssään. Tulokset osoittavat korkeakoulutettujen urapolkujen moninaisuuden. Samalla ne luovat pohjaa sille, miten sekä koulutus- ja työllisyyspolitiikassa että koulutuksen ja ohjauksen kentillä voidaan tunnistaa ja tukea erilaisia korkeakoulutettujen urapolkujen rakentumisen tapoja.
Yhteisöllinen luovuus ja ekspansiivinen oppiminen harjoittelukoulun Muutoslaboratoriossa
Authors: Hyrkkö Sakari , Kajamaa Anu
Published: December 2021

Kulttuurihistoriallisen toiminnan teorian näkökulmasta luovuus ei näyttäydy vain yksilön kognitiivisena ilmiönä vaan yhteisöllisenä toimintana, joka tähtää jaettujen käytäntöjen uudistamiseen. Yhteisöllisen luovuuden on havaittu kytkeytyvän tiiviisti yhteisöllisen oppimisen muotoihin. Toiminnan teoreettisia empiirisiä tutkimuksia luovuuden ja oppimisen yhtymäkohdista on silti niukasti. Esittelemme tapaustutkimuksen suomalaisesta harjoittelukoulusta, jossa oli ilmennyt jännitteitä ja konflikteja tulevan opetussuunnitelmauudistuksen myötä. Ekspansiivisen oppimisen teoriaan pohjautuvassa Muutoslaboratorio-kehittämishankkeessa opettajaryhmä kehitti koululle uuden pedagogisen tiimityöskentelyn ja johtamisen toimintamallin. Tutkimme, millaisia luovia tekoja Muutoslaboratoriossa ilmeni, ja millä tavoin yhteisöllinen luova prosessi edisti osallistujien ekspansiivista oppimista. Havaitsimme ”luovia harppauksia”: uudenlaisia työtoiminnan käsitteellistyksiä, jotka muodostuivat vuorovaikutuksessa yksittäisten luovien tekojen ketjuista. Ne saivat alkunsa työtoiminnan analysoinnissa esiin nousseista ristiriidoista ja tukivat ryhmän ekspansiivista oppimista tarjoamalla ristiriitoihin luovia ratkaisuaihioita. Kehittämällämme analyysimenetelmällä yhteisöllistä luovuutta voidaan tarkastella ekspansiivisen oppimisen taustalla vaikuttavana mikrotason vuorovaikutusprosessina. Tuloksia voidaan hyödyntää esimerkiksi koulutusorganisaatioiden muutosprosesseissa.