bluuebunny/crossref_metadata_2025 huggingface dataset:
Research on the Practical Path of Green Consumption in China under the Concept of Green Development in the New Era
Authors: Li Yuanyuan
Published: January 2023

Since the reform and opening up, China’s economy and society have developed rapidly and achieved great construction results. However, the rough development has brought a series of bad consequences, especially the ecological environment is getting worse and worse, so it is especially important to promote green development. Green development is to focus on the common development of economy, ecology and natural environment, to save resources and to adhere to the road of sustainable development. With the development of the times, the green consumption mode has become a new way of consumption. This mode is complementary to green development and follows the principles and concepts of green development. Green consumption is also a concrete embodiment of this concept. The purpose of this paper is to summarize the challenges faced by the implementation of green consumption policy in China and to put forward some feasible suggestions.
SYNTHESIS OF MOLECULAR IMPRINTED POLYMER SALBUTAMOL USING METHACRYLIC ACID MONOMER AND TRIMETHYL PROPANE TRIMETHACRYLATE (TRIM) AS A CROSS-LINKER THROUGH SUSPENSION POLYMERIZATION
Authors: SUSANTI IKE , SAFITRI NISA , PRATIWI RIMADANI , HASANAH ALIYA NUR
Published: January 2023

Objective: This study aims to determine the analytical performances and characteristics of MIP salbutamol made with methacrylic acid (MAA) monomer and trimethylpropane trimethacrylate (TRIM) cross-linker through suspension polymerization.

Methods: The MIP salbutamol was synthesized using suspension polymerization. The analytical performances of MIP, such as the adsorption ability, adsorption capacity and selectivity, were evaluated by Spectrophotometer UV-Vis. The physical characterization of MIP and NIP were evaluated using FTIR, TEM-EDS, Brunauer-Emmett-Teller (BET) method and Barret-Joyner-Halenda (BJH) method.

Results: Molecular Imprinted Polymer (MIP) showed better analytical performance than Non-Imprinted Polymer (NIP), the adsorption ability of MIP and NIP reached about 90.43% and 53.92%, respectively. The MIP was selective for salbutamol when compared to terbutaline and salmeterol xinafoate with an imprinting factor (IF) of 1.2841. The MIP has spherical shape particles with diameters in the range of 10-100 µm with a surface area of 185.546 m2/g, pore volume of 0.257 cm3/g, and pore size of 16.599 Å.

Conclusion: The Based on these results, MIP salbutamol, has the potential to be developed as a method for the preparation of salbutamol analysis from biological samples.
Β-LACTAMASES INHIBITOR-PRODUCING SOIL BACTERIA FOR AMPICILLIN-RESISTANT UROPATHOGENIC ESCHERICHIA COLI ISOLATE
Authors: KUSUMA SRI AGUNG FITRI , YURINA VALENTINA , RETNONINGRUM DEBBIE S. , HILMI INDAH LAILY , RAHAYU SUSI AFRIANTI , ANGGRAINI YUNI NOER
Published: January 2023

Objective: The goals of this investigation were to identify the species of the producers and ascertain the dose-dependent effect of extracellular products of Indonesian bacteria that generate β-lactamases inhibitors.

Methods: An agar diffusion technique for the lactamase inhibitor activity assay was performed. Observation of bacteria using phenotypic analysis was performed by observing colony color and cell shape morphology, biochemical assays and a series of carbohydrate fermentation tests. Bacterial identification was performed by comparing the nucleotide sequence of the 16S rDNA gene of target bacteria with available nucleotide sequences in Gene Library (NCBI). Combining data from phenotypic and genotypic analyses allowed for the identification of the producers.

Results: According to our findings, none of the bacteria's extracellular products, which contain β-lactamase inhibitors in a range of concentrations, showed a discernible impact on the values of the inhibition zone. The producers are Aeromonas popoffii, Alcaligenes faecalis, Streptomyces brasiliensis, Staphylococcus equorum, Pseudomonas putida, Pseudomonas fluorescens, Salmonella typhi, Enterobacter hormaechei, Serratia marcescens and Enterobacter sp. The highest potency of β-lactamase inhibitor was provided by the extracellular product of VR3 isolate bacteria which was identified as Serratia marcescens.

Conclusion: In conclusion, this study clearly showed that our isolated bacteria have the potential to be further investigated in order to maximize the recovery of β-lactamase inhibitor compounds.
SCREENING OF ASHITABA (ANGELICA KEISKEI K.) COMPOUNDS AS POTENTIAL MYCOBACTERIUM TUBERCULOSIS KASA INHIBITORS
Authors: ASNAWI AIYI , FEBRINA ELLIN , ALIGITA WIDHYA , KURNIA DEWI , AMAN LA ODE , YULIANTINI ANNE
Published: January 2023

Objective: Tuberculosis (TB) is a major global issue, mainly owing to the emergence of antibiotic-resistant strains of the disease's causative agent, Mycobacterium tuberculosis. The current standard of treatment for tuberculosis entails a prolonged course of antibiotics with toxic side effects and is accompanied by low patient compliance. Therefore, developing and discovering TB medications is critical to obtaining TB drugs that are more effective and sensitive to Mycobacterium tuberculosis. Ashitaba (Angelica keiskei K.) has reported that Ashitaba extract and chalcone have anti-TB properties, but the responsible compound has not been reported yet. This study aimed to identify the profile metabolites present in Ashitaba and their interaction with Mycobacterium tuberculosis KasA.

Methods: To suggest these, we used molecular docking and molecular dynamic to predict the interactions of 40 selected compounds from the Ashitaba against Mycobacterium tuberculosis KasA (PDB ID 2WGE).

Results: The results of molecular docking identified the top two compounds as xanthoangelol I (XAI) and (2E)-1-[4-hydroxy-2-(2-hydroxy-2-propanyl)-2,3-dihydro-1-benzofuran-7-yl]-3-(4-hydroxyphenyl)-2-propen-1-one (4HH), with bond free energies of-12.03 and-11.87 kcal/mol, respectively. Based on the results of molecular dynamics simulations, the XAI was stronger than 4HH in stabilizing complexes with 2WGE with total energy (ΔGbind, MMGBSA) of-54.8512 and-37.8836 kcal/mol, respectively.

Conclusion: It can be concluded that xanthoangelol I (XAI) have the most potent inhibitor of Mycobacterium tuberculosis KasA.
PREDICTION OF THE EFFECT OF SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) IN THE CYP2C9 ON WARFARIN METABOLISM BY IN SILICO STUDY
Authors: PUTRIANA NORISCA ALIZA , RUSDIANA TAOFIK , ROSTINAWATI TINA , AKBAR MOHAMMAD RIZKI , MEGANTARA SANDRA , HIDAYANTI SABRANAH
Published: January 2023

Objective: This study aimed to predict the effect of SNPs CYP2C9 s on the metabolic activity of S-warfarin in the body.

Methods: Molecular modeling was performed to obtain SNPs CYP2C9 and molecular docking was performed to predict the effect of SNPs CYP2C9 on the metabolic activity of S-warfarin.

Results: The results showed that wild-type CYP2C9 had the strongest binding affinity (∆G: -9.76 kcal/mol), indicating that wild-type CYP2C9 had the best metabolic activity compared to SNPs CYP2C9. There was a decrease in hydrogen bond formation in SNPs CYP2C9 and an increase in the distance between C7 S-warfarin and Fe-Heme in CYP2C9 SNPs when compared to wild-type CYP2C9

Conclusion: The decrease in binding affinity, decrease in hydrogen bond formation, and an increase in the distance between C7 S-warfarin and Fe-Heme on SNPs CYP2C9 indicated that SNPs CYP2C9 had decreased metabolic activity against S-warfarin which led to an increased risk of bleeding.
PATTERNS OF METHAMPHETAMINE USE AND ITS ASSOCIATIONS WITH PSYCHIATRIC SYMPTOMS IN PATIENTS UPON ADMISSION AT THE NATIONAL REHABILITATION CENTER LIDO BOGOR, INDONESIA
Authors: ROHMANIKA  , AROZAL WAWAIMULI , LOUISA MELVA , GAYATRI ANGGI , KEKALIH ARIA , MARZUKI HY JEFMAN EFENDI , LESTARI ERNIAWATI , UTAMI DIAH SETIA
Published: January 2023

Objective: Methamphetamine (MA) is a substance that is heavily abused worldwide. This present study aimed to investigate the association between the patterns of methamphetamine use and psychiatric symptoms in patients upon admission at The National Rehabilitation Center, Lido Bogor.

Methods: This was a cross-sectional study of MA abusers during the period of January 2016–December 2018 at The National Rehabilitation Center, Lido, Bogor. This study was done by assessing medical records. The inclusion criteria were MA abusers at the age of 18 y and above. Assessment of psychiatric symptoms was evaluated using Addiction Severity Index (ASI). Microsoft Excel and SPSS version 22.0 were used to process the data.

Results: The inclusion criteria were fulfilled by 1842 MA abusers. We found that 770 (41.8%) of MA abusers were assessed with psychiatric symptoms according to ASI. Depression was the most prevalent psychiatric symptom (31.9%), followed by anxiety (24.5%), and psychosis (8.9%). According to the results of multivariate analysis, the demographic profile and the mode of MA administration that are associated with the psychiatric symptoms were: female [odds ratio (OR): 1.95; 95% confidence interval (CI): 1.25–2.96, p<0.001], 5-year duration of use [OR 1.43; 95% CI: 1.43 (1.19–1.73), p<0.001], smoking as the route of administration [OR 1.3; 95% CI: 1.08–1.56, p<0.001, p = 0.006], and concomitant use with other narcotics [OR 1.76; 95% CI: 1.46–2.13, p<0.001].

Conclusion: Among MA abusers admitted to The National Rehabilitation Center, the main factors associated with psychiatric symptoms were: female, long duration of use, smoking as the route of administration, and concomitant use with other narcotics.
PROFILE OF ANTIBIOTIC RESISTANCE AGAINST INFLUENZA IN ADULT PATIENTS: A CASE STUDY AT CITY HEALTH CENTER IN INDONESIA
Authors: RAMDHANI DANNI , KUSUMA SRI AGUNG FITRI , AZIZAH SHINTA NUR , KHUMAIROH IKA , BAP HILARIUS , SEDIANA DEDE
Published: January 2023

Objective: In developing countries, cases of Haemophilus influenzae (HI) resistance to levofloxacin, cefixime, and tetracycline have become a serious problem in clinical treatment. This study was conducted to determine the antibiotic resistance profile of HI from adult patient isolates and to provide guidelines for more effective clinical treatment in Indonesia.

Methods: The patient isolate stock was rejuvenated, cultured on growth media and the Kirby-Bauer disc diffusion method was used to test for antibiotic susceptibility. Evaluation was guided by recommendations from the Clinical and Laboratory Standard Institute (CLSI).

Results: A total of 643 isolates obtained from the respiratory tract isolated and identified 73 HI strains. The resistance rates of the HI isolates to tetracycline, cefixime, and levofloxacin were 10.54 %, 4.31%, and 5.67%.

Conclusion: Cefixime showed more effective activity than levofloxacin and tetracycline to treat the HI strain.
ETHNOMEDICINAL STUDY OF UBAR KAMPUNG FOR DIABETES MELLITUS: INDIGENOUS KNOWLEDGE, BELIEF, AND PRACTICE OF MEDICINAL, AROMATIC, AND COSMETIC (MAC) PLANTS IN SUNDA REGION, WEST JAVA, INDONESIA
Authors: FEBRIYANTI R. M. , SLIKKERVEER L. J. , SPAINK H. P. , LESTARI K. , SAEFULLAH K.
Published: January 2023

Objective: Over the past several decades, ethnobotany and ethnomedicine have been considered as a more appropriate interdisciplinary approach to drug discovery involving interdisciplinary collaboration. Several studies on ethnomedicine and ethnobotany worldwide have shown that diabetes mellitus has been recognised by the traditional healer as a pathological condition which can be treated with specific medicinal plants. The starting point in an ethno-directed search for anti-diabetic plants is the identification of plant species used by local healers for this purpose. This study aims to document medicinal plants used by local communities for the treatment of diabetes mellitus.

Methods: This ethnographical study highlights the emic point of the local people to documents knowledge, belief, and practice of ubar kampung in Sunda Region.

Results: The results of this study reveals 20 of most frequently used of medicinal, aromatic, and cosmetic plants by people in Sundanese community. The majority of plant species used for the treatment of diabetes mellitus belong to the families of Asteraceae (2 species), Lauraceae (2 species), and Liliaceae (2 species).

Conclusion: Most of the medicinal plants reported in the research area are already publicly acknowledged for their medicinal properties, indicating that their pharmacological activities have been studied in different areas. Medicinal plants such Syzygium polyanthum, Moringa oleifera, Swietenia mahagoni, Allium sativum, and Cinnammomum burmanni have been widely used in several regions by various ethnic groups. Leaves are the most frequently used plant part. In general, infusion and decoction are the most common plant preparation methods in the research area.
THE POTENTIAL OF LANGIR (ALBIZIA SAPONARIA LOUR.) STEM BARK AS ANTI-DANDRUFF: IN SILICO AND IN VITRO STUDIES
Authors: HIMANIARWATI  , ARBA MUHAMMAD , SUSILAWATI YASMIWAR , MUSTARICHIE RESMI
Published: January 2023

Objective: Dandruff is a scalp problem that occurs in almost all people in the world. The main cause of dandruff is the growth of fungus on the scalp. This study aims to evaluate the antifungal activity of the Langir bark against Malassezia furfur, in vitro and in silico. 
Methods: In vitro testing was carried out using the agar diffusion method with paper disks to calculate the inhibition zones of the Langir stem bark extract and fractions, while the in silico test was carried out using the molecular docking method using Lanosterol 14-alpha demethylase receptors with a homology model using 5 compounds from the genus Albizia as ligands.
Results: Antifungal activity of Langir bark extract showed significant activity in all concentrations (5-20%), and also for all fractions (p<0.05). However, the water fraction had better activity than others, with an inhibition zone of 17.33 mm at a concentration of 15% and 18.67 mm at a concentration of 20%, while the positive control (ketoconazole 1%) had an inhibition zone of 16.67 mm. Furthermore, the in silico test revealed that the 5 metabolites in Langir plant provide better binding energy than ketoconazole (-10.1 kcal/mol), namely, Tamarixetin 3-rutinoside (-10.7 kcal/mol), Quercetin 3-rhamnosyl-galactoside (-10.4 kcal/mol), Albiziasaponin A (-11.6 kcal/mol), Albiziasaponin C (-11.9 kcal/mol) and Albiziasaponin D (-11.9 kcal/mol). 
Conclusion: The water fraction of Langir bark has activity in inhibiting the growth of M. furfur so that it can be developed as a therapeutic alternative for anti-dandruff.
THE EFFECT OF CO-PROCESSED EXCIPIENTS DURING FORMULATION AND EVALUATION OF PEDIARIC LEVETIRACETAM ORODISPERSIBLE TABLETS IN RATS
Authors: TEAIMA MAHMOUD H. , EL MESSIRY HUSSIEN MOHAMED AHMED , DAHI OSMAN TASNEEM , A. EL-NABARAWI MOHAMED , A. HELAL DOAA
Published: January 2023

Objective: The main aim of this research was to make cost-effective taste-masking oral pediatric orodispersible tablets (ODTs) of Levetiracetam as an antiepileptic drug (AED) using various co-processed excipients by direct compression method.
Methods: Eight kinds of ready-made co-processed excipients in addition to sucralose and menthol as a sweetener, were utilized. The weight variation, drug content, friability, in vitro disintegration, dissolution time, hardness, thickness, and pharmacokinetics of the produced ODTs were determined.
Results: The optimized formula (F5) containing Pharmaburst® 500 showed the shortest disintegration time (11.66 sec) and more than 98% of Levetiracetam within 10 min (Q10). The Pharmacokinetic study of this optimum formula (F5) in rats using an HPLC-UV detector showed 26.904±2.027 ng/ml as the Cmax and 101.935±0.894 h ng/ml as AUC compared to commercial Tiratam® solution 10.421±0.295ng/ml and 23.135±0.43 h ng/ml respectively.
Conclusion: Levetiracetam orally orodispersible tablets were successfully prepared with acceptable hardness, satisfactory taste, and rapid disintegration in the oral cavity avoiding first-pass metabolism to yield the desired rapid effect in facing epilepsy for patients who experience dysphagia like pediatric and geriatric. In addition to the unconsciousness of the epileptic patient followed the seizure attack.
CENTRAL COMPOSITE FACE-CENTERED DESIGN-BASED OPTIMISATION, DEVELOPMENT AND CHARACTERISATION OF FAVIPIRAVIR-LOADED PLGA NANOPARTICLES
Authors: R VENKATA KAVYA , B. JEEVANA JYOTHI
Published: January 2023

Objective: The objective of this study is to fabricate favipiravir-loaded PLGA nanoparticulate systems that can increase the solubility along with the sustained release of favipiravir.
Methods: The favipiravir-loaded Poly (D, L-lactic-co-glycolide) (PLGA) nanoparticulate systems were prepared by the nanoprecipitation method. A 3-factor, 2-level central composite face-centered design was employed to study the effect of formulation variables having a concentration of PLGA, polyvinyl alcohol (PVA) and stirring rate as critical formulation attributes and particle size, drug entrapment efficiency, and percentage cumulative drug release as critical quality attributes on prepared favipiravir nanoparticles. Drug interaction studies were performed by FTIR and DSC. Surface morphology was analysed by scanning electron microscopy (FEI Quanta 250 FEG, USA). Particle size, zeta potential, and polydispersity index were analysed by the nanoparticle analyser SZ-100 (HORIBA Scientific nanopartica, Japan). In vitro drug release studies were performed using a UV-Visible spectrophotometer at λmax 234 nm. In vitro drug release data obtained was fitted into various mathematical kinetic models.
Results: The numerical optimization process predicted the level of PLGA concentration as 69.96 mg, PVA concentration as 4.99%, and stirring rate as 799 rpm for the optimised formulation. The low percentage of relative error for the optimised formulation confirms the validation of the model. The optimised formulation had a 77.65% entrapment efficiency with a particle size of 109.7 nm and the percent cumulative drug release showed 86.46% drug release over 720 min. The drug release was found to follow first-order release kinetics with anomalous non-Fickian diffusion kinetics.
Conclusion: Hence, such an attempt at fabrication of favipiravir-loaded PLGA nanoparticulate systems may be useful for sustained release of drug over 720 min.
IMPROVING SOLUBILITY OF METHOTREXATE BY SOLID DISPERSION
Authors: MOHAMAD ALI ALALI MUQDAM MAHDI , AL-MOUSAWY JINAN M. , KADHIM ZAHRAA MOHAMMED , ASHOOR JAMAL ALI
Published: January 2023

Objective: Methotrexate (MTX) is a folate antimetabolite used for the management of neoplastic diseases like leukemia and breast cancer, Methotrexate is also used in the treatment of psoriasis as well as rheumatoid arthritis. The goal of this research was to improving the solubility and dissolution profile of methotrexate solid dispersion by using different polymers.
Methods: A total six formulas were prepared as solid dispersion of methotrexate by solvent evaporation method by using polyethylene glycol (PEG-4000) and poly Vinyl pyrolidone (PVP-K30) as polymeric solubilizer in ratio (1:1,1:2,1:4), Then the solid dispersion of methotrexate were evaluated by solubility test, permeability test and FTIR study.
Results: All six solid dispersion formulas showed a significant improvement in the solubility of methotrexate, and the formulations demonstrated improved in the rate of drug release of approximately 99.8±0.9 within 60 min. FTIR study for F3 and F6 show no drug-excipients interaction.
Conclusion: Methotrexate was successfully enhanced its water solubility by using solid dispersion.
AN OVERVIEW: DEVELOPMENT OF COLON DRUG DELIVERY SYSTEM AND ITS APPLICATION AND LIMITATIONS
Authors: SOPYAN IYAN , KOMARUDIN ANITA DEWI PERMATASARI , HUANG JESSICA ANLIANI , K. S. INSAN SUNAN
Published: January 2023

There are various routes of drug administration. Oral administration is considered the most preferred route in drug administration for systemic effects, but the oral administration is not suitable for people with ulcerative colitis, crohn's disease, bowel cancer, diarrhea, treatment of diseases that sensitive to circadian rhythms such as asthma and angina, as well as for steroids administration. The delivery of targeted drugs has the goal of achieving the desired therapeutic profile by delivering the drug to the target site. This study conducted by reviewing related articles based on specify keywords on Science Direct database that has been published for the last 10 y. In recent decades, research has been conducted to develop methods that can target drugs to specific organs. The focusing on targeted drug delivery system to the colon, the various ways that were carried out for its approach, as well as the evaluation. By this study, some challenges in the colon drug delivery system could be overcome along with new approaches.
AHORRO DE LOS HOGARES MEXICANOS ANTES Y DURANTE LA PANDEMIA DE LA COVID-19
Authors: Villar Hernández Bartolo de Jesús , Jiménez Alba María Guadalupe , Sánchez Carrera Edgar Javier
Published: January 2023

En este trabajo de investigación analizamos la tasa de ahorro de los hogares mexicanos antes y durante la pandemia por la COVID-19. El objetivo central es actualizar el conocimiento sobre el tema, para así cuantiﬁcar el efecto de las variables socioeconómicas y sociodemográﬁcas determinantes del ahorro. Aplicamos el método econométrico de regresión cuantil para los datos de la Encuesta Nacional de Ingresos y Gastos de los Hogares de 2018 y 2020. Los resultados obtenidos comprueban la heterogeneidad de la inﬂuencia de las variables seleccionadas según el cuantil de la tasa de ahorro modelada, así como el cambio dinámico del efecto asociado a los determinantes y de la tasa de ahorro como consecuencia de la crisis económica derivada por la COVID-19.
 
ON THE MEXICAN HOUSEHOLDS’ SAVINGS BEFORE AND DURING THE COVID-19 PANDEMIC
ABSTRACT
In this research paper we analyze the Mexican household saving rates before and during the COVID-19 pandemic. Our key research goal is to update the knowledge on this topic and quantify the effects of socioeconomic and sociodemographic covariates as household saving determinants. We apply a quantile regression model taking data from the 2018 and 2020 Encuesta Nacional de Ingresos y Gastos de los Hogares. Our results provide evidence about the heterogeneity of the effects of socioeconomic and sociodemographic household saving determinants, also about the dynamic change of effects associated with the determinants and the household saving rate, as a consequence of the economic crisis derived from COVID-19.
A Review on Vehicle Suspension with Urethane Buffer
Authors: Patil Shubham S. , Inamdar Prof. Dr. Kedar H.
Published: January 2023

Abstract: Elastomers are extensively used in the automobile industry due to their excellent damping and energy absorption characteristics and low cost, to isolate the structures from vibration and shock loads. In this study, the aim is to analyse the effect of an elastomer buffer implanted in the suspension of an automobile. In this study, the effect of coil spring with and without polyurethane buffer on spring damping capabilities will be analysed. In new vehicle, performance of the suspension is better, but after some years performance of the suspension is reducing. Which also impact on suspension life, so performance of the suspension will be increased by using urethane buffer
Community aqueducts in Colombia and their struggle for legal recognition
Authors: Platarrueda Irene
Published: January 2023

In Colombia there are thousands of community aqueducts that supply water to remote rural communities and peripheral urban settlements. These community aqueducts have united in a National Network to fight for legal recognition and support, since Colombia’s neoliberal policies don’t acknowledge their communitarian nature and have imposed legal requirements that push them towards privatization. Departing from a Latin American political ecology perspective, the paper discusses how this struggle is part of a broader regional movement in which a different rationality between humans and nature, not mediated by economic interests, is fighting to survive and advance in contestation to the hegemonic capitalist model. I argue that community aqueducts put in practice the defense of water as a common in an autonomous exercise of governance that contributes to the construction of territories in Latin America.
Superplants: hegemonic masculinities holding up the green transition
Authors: Hogan Mary
Published: January 2023

This paper departs from a consideration of an emerging popular discourse concerning a plant-based mining technology called agromining. Agromining is defined by its inventors as a method for mining metals with plants, encompassing a chain of procedures from the cultivation of metal-absorbing plants to the marketing of the pure metal extracted from them. It is being developed and marketed by scientists as an environmentally friendly alternative to traditional mining that can support technological shifts needed for the green transition. Following the characterization within this popular discourse of the agromining plants as “super”, the hegemonic logics behind it are exposed and used to unpack the agendas, political biases, and naturalized ideologies behind green technologies. This paper investigates why being super is so appealing and what logics are upheld and reproduced by prioritizing superness. Three central elements construct the main argument of this paper: hegemonic masculinity, the depoliticization of climate change, and the lack of a plural democratic space to address the global ecological crisis. These points give context to why superness may be an attractive quality for a green technology and help to problematize the neutrality of science-backed solutions to ecological problems. Possibilities for refusal and resisting both hegemonic masculinity and the dominant logics that reproduce it are discussed with contributions from Feminist, Queer, and Crip theories.
panoramic view to the evolution of three scientific communities in chilean academia 2012-2022
Authors: Gibert Galassi Jorge , Espina Bocic Paola
Published: January 2023

The scientific community (or the academic profession) is one of the key players in the global and local dynamics of R&D and affects enormously the performance of contemporary societies. Nevertheless, historical, and institutional conditions strongly affect the magnitude and form of scientific and technological production in the various scientific communities around the globe. During the 20th century, the scientific community has been described as Merton's CUDO, followed by Kuhn's notion of paradigm, and finally in terms of post-normal science debates, mode two, and triple helix. This paper compares two measurements (survey-2012, and survey 2022), describing the evolution of a set of characteristics, especially incentives and values, ​​​​in three scientific communities (astronomers, sociologists, and molecular biologists) as representative of three epistemic practices: exact sciences, natural sciences, and social sciences. After an introduction describing the context of knowledge production in Chile, the paper compares results from both surveys, trying to understand the differences and aspects in common in a transversal way through three dimensions. The results are the outcome of two online surveys applied to a statistically representative of the communities studied.
Análisis de las lecturas de caricaturas periodísticas por parte de universitarios
Authors: Urrego Carlos , Ramírez Llanos Juan Sebastián
Published: January 2023

El presente artículo recoge las concepciones construidas a través de las caricaturas periodísticas publicadas en medios de comunicación masivos colombianos, y la manera en la que estudiantes universitarios resignifican o apropian dicho producto comunicativo. Luego de revisar los elementos conceptuales acerca de este producto del género periodístico de opinión en el que se definen sus tipos, categorías, usos, recursos gráficos utilizados y el impacto que tienen en la construcción de realidad, se aplicó una encuesta a ciento cincuenta universitarios, con quienes se analizó la forma de lectura de caricaturas para identificar los cambios de comprensión, estado de ánimo y tipo de recibimiento a la información icónica allí consignada, todo ello a través de un instrumento de medición basado en aspectos de la escala de Likert para que los participantes pudieran calificar un grupo de diez caricaturas publicadas. Se buscó comprender la manera en la que el público objeto resignifica o apropia dicho producto periodístico y el impacto que tiene en la forma de leer los acontecimientos. Se concluye que el género periodístico de opinión y la caricatura —como una de sus expresiones— mantiene una relación estrecha con la forma en la que los universitarios entienden su contexto, pero se confirma la brecha existente entre la información y este grupo etario. Se encontró que los jóvenes que consumen caricaturas las utilizan para reafirmar sus convicciones, pero poco para hacer lecturas de realidad disímiles a las propias.
Coronavirus Causes Diabetes in People who Did Not Have Diabetes Before They Contracted COVID-19
Authors:   Department of ChemistryandBiochemistry, College of Medicine, Al-Nahrain University, Kadhimiya, Baghdad, Iraq, Y.Jameel Ziena , B.Hasan Bassam ,   Department of Chemistry, College of science, Al-Nahrain University, Jadriya, Baghdad-Iraq
Published: January 2023

Coronavirus disease infects the respiratory system through binding to the receptor of angiotensin-converting enzyme2(ACE2), Symptoms of the disease develop within 5-6 days after infection, accompanied by mild to moderate symptoms in the initial stage of the disease, and continue for 10-15 days. But it has the potential to develop into severe acute respiratory distress syndrome (ARDS), which leads to the destruction of multiple organs in the body, including the beta cells in the islets of Langerhans in the pancreas, causing type 1 or type 2 diabetes and high blood sugar. The aim of the study is to detect diabetes mellitus in people with COVID-19 who did not have diabetes and did not have a family history of the disease before they were exposed to the virus. COVID-19 was diagnosed by nasal swab through PCR Real-time. The detection of diabetes was through blood tests such as blood sugar, and glycated hemoglobin (HbA1C), and the acute stage of the infection was detected through Dimer, LDH, Ferritin, and C -reactive protein (CRP) tests. From the results that obtained during the research, it was found that the patient percentage with diabetes due to the virus is 20% of type I, while 80% diabetes of type II.
Identifikasi Panen, Pasca Panen dan Kelembagaan Usahatani Kopi
Authors: Adri Adri , Firdaus Firdaus , Yardha Yardha
Published: January 2023

Identifikasi merupakan langkah awal yang penting dalam rangka memahami kondisi sistem usahatani disuatu wilayah. Hasil indentifikasi akan menentukan keputusan penting dalam pengembangan sistem usahatani (Hendayana, R. 2007). Keberhasilan usahatani tidak hanya tergantung pada faktor teknis dan biologis tetapi juga tergantung pada faktor sosial ekonomi dan kelembagaan. Oleh karena itu sumberdaya alam, sumberdaya manusia, teknologi dan kelembagaan adalah faktor - faktor penggerak dalam peningkatan produktivitas, kualitas dan nilai tambah usahatani. Empat faktor tersebut merupakan faktor kecukupan untuk mencapai suatu keragaan usahatani yang dikehendaki, artinya, satu atau lebih dari faktor tersebut tidak ada atau tidak sesuai dengan persyaratan kecukupan yang dimaksud, maka usahatani yang akan dikembangkan tidak dapat menghasilkan keragaan usahatani seperti yang diinginkan.
Estimasi Panjang Antrian Pada Simpang Bersinyal Dengan Menggunakan Artificial Neural Network
Authors: Respati Sara , Isram Mohamad , Fatmawati Fatmawati , Kusrini Sri
Published: January 2023

Signalized intersections are nodes in the transportation network where vehicles in different directions meet and are critical points for congestion. Vehicle queue length is one of the performance parameters of a signalized intersection. Long queues of vehicles are at high risk of accidents involving many vehicles. Feedback signal control (actuated signal control) can be used to improve intersection performance. One of the variables that can be used as a feedback input is the length of the vehicle queue. Traffic in Indonesia is mixed traffic where various types of vehicles use the same road lanes and with low lane discipline. This causes the traffic system to become complex and to be stochastic and non-linear. Queue length modeling using a static linear algorithm is unable to capture the phenomenon of this complex traffic system. Therefore, this study aims to build a queue length model based on machine learning, that is, using an artificial neural network (ANN). This model studies traffic systems with historical data so that through the training process it can model queue lengths with a good degree of accuracy. An estimation model was built and applied to a section of the Muara Rapak signalized intersections, Balikpapan. Data on queue length for 10 days, 2 hours/day, obtained using CCTV and direct field surveys. The results of the model test show that ANN has a good level of accuracy with MAE, RMSE and MAPE of 3.8 m, 4.9 m and 6%, respectively.
Peramalan Ekspor Karet Provinsi Jambi dengan Model Seasonal ARIMA
Authors: Atmanegara Eviyana
Published: January 2023

The industrial sector contributed the most to total non-oil and gas exports in Jambi Province. Rubber and its processed products are the main export commodities in the industrial sector. The export value of rubber and its products increased in 2017 but decreased again from 2018 to 2020. The decline in exports harmed the economy in Jambi Province. It is necessary to predict the export value of rubber and its products in the coming period. Forecasting is done on time series data using the ARIMA and SARIMA models. The best model for modeling the export value of rubber and its products in Jambi Province is SARIMA (0,1,1)(0,0,1)12. It is predicted that the export value of rubber and its processed products will decrease by around 4 percent in 2022. And decrease by around 5 percent in 2023. The results of this forecast can be used as an early warning in making policies related to exports in the coming period.
Pengembangan Kulit Manis Mendukung Pembangunan Pertanian Kerinci
Authors: Firdaus Firdaus , Izhar Lutfi , Salwati Salwati
Published: January 2023

Cinnamon is one of leading plantation commodity in Jambi Province, especially in Kerinci Regency, and has an enormous portion as the country's revenue. In addition, cinnamon is a multi-functional plant that can be used in industry, besides functioning as land conservation. However, seed support and technology studies need to be more considered and implemented. The purpose of this paper was to describe the seeds and cultivation innovation technology for cinnamon in Jambi Province. The study was carried out in several sub-districts in Karinci in 2018, using selected mother trees, demonstration plot for harvest and post-harvest analysis. The results show that recently the need for cinnamon seeds still has not sufficient. However, more than 4.000 cinnamon seeds have been distributed and provided with technology assistance for local Kerinci farmers. Dissemination of institutional cinnamon production guidelines and certification of cinnamon seedlings has been carried out in several farmers. The package of cinnamon technology components has been studied and disseminated within this Kerinci areas.
Sistem Pengawasan Perizinan Bidang Lingkungan Hidup Terhadap Perizinan Berusaha Bidang Kehutanan dan Pertambangan di Indonesia
Authors: Helmi Helmi
Published: January 2023

UU No. 32 Tahun 2009 tentang Perlindungan dan Pengelolaan Lingkungan Hidup mengehandaki sistem pengawasan terhadap pengelolaan lingkungan hidup secara terpadu. Kenyataan, sistem pengawasan perizinan bidang lingkungan hidup berjalan sendiri-sendiri secara sektoral. Kondisi umum sistem pengawasan perIzinan bidang lingkungan hidup ini mengakibatkan sulitnya keterpaduan pengelolaan lingkungan hidup yang sebenarnya merupakan asas penting dalam hukum lingkungan yang terdapat pada UU-PPLH. Dengan kata lain, cita-cita keterpaduan dalam UU PPLH, tidak dapat dilaksanakan terhadap sistem pengawasan perizinan bidang kehutanan dan pertambangan. UU-PPLH sebagai tidak sepenuhnya bisa diterapkan pada sistem pengawasan perIzinan yang diatur oleh UU Kehutanan dan Pertambangan. Selain substansinya banyak tidak sesuai juga norma hukum pengawasan perizinan pada UU-PPLH tidak lebih tinggi dibandingkan dengan UU Kehutanan dan UU Pertambangan. Dalam rangka pembentukan sistem pengawasan perizinan lingkungan hidup secara terpadu, maka pengaturan Pengelolaan Lingkungan Hidup Nasional dalam satu UU sangat diperlukan dalam rangka mewujudkan pembangunan berkelanjutan di Indonesia.
Analisa Kepuasan Konsumen Gojek di Kota Semarang Melalui Service Quality, Customer Requirement, dan Technical Response
Authors: Wibowo Bagus Yunianto , Ayuwardani Mellasanti , Setyawan Nanang Adie
Published: January 2023

Gojek merupakan perusahaan teknologi yang bergerak di bidang jasa angkutan transportasi yang didirikan oleh Nadiem Makarim dan timnya pada tahun 2010 di Jakarta. Gojek memiliki tujuan memberikan kenyamanan terhadap pelanggan, namun fakta di lapangan menunjukkan masih banyak pelanggan mengeluh terkait kualitas layanan Gojek, mulai dari kedatangan driver tidak tepat pada waktu, driver serampangan, kenaikan harga jasa. Dalam hal ini untuk memberikan masukan terhadap pihak gojek sebagai sarana peningkatan kepuasan pelanggan, Responden dalam penelitian ini adalah para pengguna layanan Gojek dari mahasiswa maupun pekerja di kota semarang dengan sampel 100 responden dari keseluruhan populasi. Penelitian ini menggunakan teknik analisis faktor konfirmatori dan maximum likehood estimation pada SEM (Structural Equations Modeling) dari paket statistik AMOS 24.0 (Analysis of Moment Structure). Teknik pengumpulan data menggunakan kuesioner dengan insidential sampling. Hasil estimasi parameter sesuai dengan hipotesis bahwa Service Quality  secara signifikan mempengaruhi Customer Satisfaction  dengan nilai critical ratio (c.r) 3,471 dan P-Value ***, Customer Requirement berpengaruh positif terhadap Customer Satisfaction  dengan nilai critical ratio (c.r) 3,639 dan P-Value ***, dan Technical Response berpengaruh positif terhadap Customer Satisfaction  dengan nilai critical ratio (c.r) 4,177 dan P-Value ***. Dari penelitian ini dapat disimpulkan bahwa pasca pandemi covid-19 saat ini para konsumen masih sangat antusias untuk menggunakan jasa Gojek guna memudahkan keperluan sehari-hari.
Perlindungan Peserta Magang Dalam Praktik Unpaid Internship Ditinjau Dari Peraturan Ketenagakerjaan Di Indonesia
Authors: Milenia Febi Cindy , Karsona Agus Mulya , Singadimedja Holyness N
Published: January 2023

Pada masa sekarang ini, marak diketahui mengenai pengadaan program magang tanpa pemberian uang saku (unpaid internship). Alasan perusahaan yang menyelenggarakan unpaid internship yaitu untuk merekrut tenaga kerja magang dari kalangan mahasiswa dan fresh graduate yang belum memikirkan uang dan hanya mencari pengalaman kerja. Artikel ini bertujuan untuk menganalisis legalitas dari praktik unpaid internship serta perlindungan hukum terhadap peserta magang dalam praktik unpaid internship ditinjau dari peraturan ketenagakerjaan yang ada di Indonesia, khususnya Undang-Undang Republik Indonesia Nomor 13 Tahun 2003 tentang Ketenagakerjaan dan Peraturan Menteri Ketenagakerjaan Republik Indonesia Nomor 6 Tahun 2020 tentang Penyelenggaraan Pemagangan di Dalam Negeri. Penelitian ini dijalankan dengan menggunakan metode yuridis normatif. Hasil yang didapat dari penelitian ini ialah apabila ditinjau dari Undang-Undang Ketenagakerjaan dan Permenaker No. 6 Tahun 2020, sudah menjadi kewajiban bagi perusahaan untuk memberikan uang saku bagi peserta pemagangan dan sudah seharusnya peserta magang unpaid internship dilindungi sesuai dengan peraturan perundang-undangan ketenagakerjaan yang berlaku.
Analisis Putusan Mahkamah Konstitusi No.15/PUU-XV/2017 Tentang Pengujian Undang-Undang No. 28 Tahun 2009 Tentang Pajak Daerah Dan Retribusi Daerah Terhadap Pasal 1 Ayat (3), 27 Ayat (1), Dan 28d Ayat (1) UUD 1945
Authors: Adelina Andi Aliya
Published: January 2023

Pada tahun 2017 dalam perkara Putusan MK Nomor 15/PUU-XV/2017, dilakukan judicial review terhadap Pasal 1 angka 13, Pasal 5 ayat (2), Pasal 6 ayat (4), dan Pasal 12 ayat (2) Undang-Undang PDRD yang diuji dengan Pasal 1 ayat (3), Pasal 27 ayat (1) dan Pasal 28D ayat (1) UUD 1945. Pengujian tersebut mempersoalkan alat berat yang tetap dikenakan pajak PKB dan BBNKB sementara berdasarkan Putusan MK Nomor 3/PUU-XIII/2015, alat berat bukanlah kendaraan bermotor dengan membatalkan norma hukum yang ada dalam Penjelasan Pasal 47 ayat (2) huruf e UU LLAJ. Pengujian UU PDRD ini menimbulkan adanya dugaan pelanggaran asas nebis in idem, mengingat telah dilakukan permohonan pengujian norma yang sama seperti pada perkara Putusan MK Nomor 1/PUU-X/2012. Selain itu, persoalan amar putusan yang dipandang tidak efektif dengan memberikan jangka waktu perbaikan undang-undang setelah menyatakan norma tersebut inkonstitusional, sehingga perlu dilakukan penelusuran mengenai Putusan MK Nomor 15/PUU-XV/2017. Metode penelitian yang digunakan dalam studi kasus ini merupakan yuridis normatif yang bersifat deskriptif analitis dengan menggunakan teknik studi kepustakaan. Hasil penelitian menunjukan bahwa Putusan MK Nomor 15/PUU-XV/2017 tidak melanggar asas Nebis In Idem dikarenakan terdapat batu uji yang berbeda, alasan Permohonan Pemohon yang berbeda serta Mahkamah memiliki pertimbangan hukum yang juga berbeda dikarenakan terdapatnya suatu keadaan hukum baru. Selanjutnya, bentuk amar Putusan MK Nomor 15/PUU-XV/2017 adalah tidak tepat karena bentuk amar putusan tersebut tidak termasuk dalma bentuk Putusan MK yang sudah diamanatkan undang-undang maupun perkembangan hukum, juga dampak keberadaan putusan tersebut yang menyebabkan kerugian yang berkelanjutan (continously damage).
Praktik Pemeriksaan Saksi Dengan Menggunakan Teleconference Pada Pengadilan Agama Demi Mewujudkan Asas Sederhana Cepat Dan Biaya Ringan
Authors: Utami Vidya Khairina , Artaji Artaji , Kusmayanti Hazar
Published: January 2023

Pengadilan Agama adalah pengadilan yang mengadili perkara privat antar individu yang beragama Islam dan menggunakan syariat hukum Islam dalam proses beracaranya. Ketentuan pada Pasal 54 Undang-Undang Peradilan Agama menyebutkan bahwa apabila terdapat suatu hal yang tidak diatur secara khusus pada Undang-Undang Peradilan Agama, maka akan tetap mengacu kepada hukum acara perdata yang berada di lingkungan Peradilan Umum, yaitu salah satunya HIR/Rbg. Perkembangan teknologi yang terjadi membuat munculnya PERMA No.1 Tahun 2019 dan membuat perubahan pada litigasi terutama pembuktian, yaitu pemeriksaan keterangan saksi menggunakan teleconference. Praktik ini menimbulkan perbedaan dan kendala dengan syarat formil dalam sahnya alat bukti saksi pada HIR/Rbg. Efektifitas dan efisiensi beracara dengan menggunakan teleconference dalam pemeriksaan saksi menggunakan teleconference agar dapat terwujudnya asas sederhana, cepat dan biaya ringan. Penelitian dilaksanakan dengan menggunakan metode yuridis normatif dengan metode analisis yuridis kualitatif, yaitu menggabungkan data primer yang didapatkan di Pengadilan Agama Jakarta Pusat dan Pengadilan Agama Jakarta Barat dengan data sekunder. Pemeriksaan saksi dengan menggunakan teleconference pada dasarnya tetap dilaksanakan secara langsung dan dalam waktu yang bersamaan pada saat persidangan, meskipun saksi hadir secara virtual. Praktik ini tidak bertentangan dengan HIR dan Rbg. PERMA No.1 Tahun 2019, HIR, dan Rbg dianggap kurang efektif dan efisien dalam membantu terwujudnya asas cepat, sederhana dan biaya ringan. Perwujudan asas sederhana, cepat dan biaya ringan tetap terpenuhi dalam praktik pemeriksaan saksi dengan menggunakan teleconference, baik dari segi prosedur administrasi, prosedur pemeriksaan, jangka waktu, dan biaya perkara. Kebutuhan dari seluruh Pengadilan Agama dalam melaksanakan pemeriksaan saksi dengan menggunakan teleconference perlu diperhatikan kembali oleh Mahkamah Agung.
Penyelesaian Pembiayaan Macet Pada Fasilitas Pinjaman Usaha di Marketplace Dalam Praktik
Authors: Widaningtyas Syifa Afiani , Murwadji Tarsisius , Mulyati Etty
Published: January 2023

Tujuan dari penelitian ini adalah untuk mengetahui dan menganalisis secara yuridis tanggung jawab dan upaya terhadap penyelesaian pembiayaan macet yang terjadi dalam praktik penyaluran fasilitas pinjaman di marketplace oleh Lembaga Keuangan Bank. Metode penelitian yang digunakan adalah yuridis normatif dengan spesifikasi penelitian deskriptif analitis. Hasil penelitian menunjukkan bahwa tanggung jawab dari para pihak dalam penyediaan fasilitas pinjaman di marketplace dibebankan kepada pihak lembaga keuangan bank. Selain itu, upaya penyelesaian yang dapat dilakukan oleh lembaga keuangan bank adalah berupa hapus buku sebagai upaya penyelesaian akhir sebagaimana ditentukan dalam Peraturan Otoritas Jasa Keuangan Nomor 40/POJK.03/2019 tentang Penilaian Aset Bank Umum. Namun, hapus buku dalam hal ini tidak menghapuskan hak untuk menagih miliki bank karena perikatan yang terbentuk antara bank dengan pelaku usaha melalui perjanjian pembiayaan belum terhapus dan masih mengikat bagi para pihak.
Pengaruh Sensasi Dan Repetisi Iklan Terhadap Efektivitas Iklan Pada Iklan Pasta Gigi Dalam Menciptakan Proses Pembelajaran Konsumen
Authors: Hasiholan Leonardo Budi , Amboningtyas Dheasey
Published: January 2023

Tujuan Penelitian ini ingin menganalisis pengaruh sensasi danrepetisi iklan terhadap efektivitas iklan pada pasta gigi dalam menciptakan proses pembelajaran konsumen. Perkembangan teknologi informasi yang berkembang sangat pesat saat ini berpengaruh bagi masyarakat dalam mendukung berbagai kegiatan bisnis baik besar maupun kecil agar dapat dikenal secara global. Berdasarkan hasil penelitian ini diharapkan menjadi acuan bagi penelitian di  masa mendatang yang meneliti mengenai sensasi iklan dan repetisinya dan memberikan kontribusi terkait efektivitas iklan di media televisi dan audiovisual lainnya. Penelitian ini menggunakan desain survey, yaitu penelitian yangmengambil sampel dari suatu populasi dan menggunakan kuesioner sebagaialat pengumpulan data pokok. Populasi dari penelitian ini adalah seluruhmasyarakat di Kota Semarang. Sampel dalam penelitian ini diambil 100 orangmasyarakat sebagai sampel penelitian dengan menggunakan metode purposivesampling sebagai teknik pengambilan sampel. Adapun analisis data dalam penelitian ini menggunakan regresi linier berganda. Studi Pustaka adalah teknik untuk mendapatkan data teoritis atau data sekunder dalam penelitian. Studi Pustaka dilakukan dengan mempelajari buku, literatur, dokumen resmi, catatan dan transkrip, yang terkait dengan penelitian.