bluuebunny/crossref_metadata_2025 huggingface dataset:
GFWA - Generating Fresh Water from the Atmosphere
Authors: Mandala Ishaan
Published: December 2024

Drought is a global problem with widespread economic and environmental ramifications, affecting millions worldwide. Traditional water supply methods became unsustainable and expensive. Therefore, there is a need to find cost-efficient ways to generate water without harming the ecosystem. The project aims to test the effectiveness of the atmospheric water generation prototype “GFWA” using heat compression and the Peltier effect. The hypothesis is that GFWA can generate a minimum of two fl. oz of water daily from the atmosphere, providing a cost-efficient solution for households to produce clean drinking water.
The GFWA prototype was built by placing the Peltier chip in the middle to optimize heat flow. Materials used to construct the prototype are a PC heat sink, a small heat sink rack, a Peltier chip, ceramic filter balls, and a DC Jack. The experiment was conducted for 11 days, where the daily amount of water generated and pH levels were monitored to ensure water quality.
Discovery shows that larger heat sinks generated more water, and the device would need to be larger or run longer to be cost-effective. The results showed that GFWA generated approximately four fl oz of water per day, which supports the hypothesis. GFWA produced water with lesser ppm levels than other common sources and was somewhat cost-effective.
These findings are significant as they introduce a new and efficient way to solve drought and generate water. Rather than relying on available solutions like rainwater harvesting, GFWA offers a solution that can generate water from an always-available resource.
Transfer of sensorimotor adaptation reveals independent prosodic representation after segment-prosody coordination in speech production
Authors: Zeng Yuyu , Parrell Benjamin , Niziolek Caroline A
Published: December 2024

In speech production, there is a long-standing debate regarding whether word-level prosodic structure has an independent representation separable from segments. Using a novel assay of sensorimotor adaptation, we observe straightforward evidence supporting an independent prosodic structure even after its coordination with the segments. Participants exposed to opposing formant perturbations applied to the two syllables of a single trained word (e.g., “bedhead” → “bidhad”) adapted separately to counteract the syllable-specific perturbations (i.e., producing “badhid”) and, critically, transferred the learned adaptation to untrained words based purely on shared prosodic structure (words with the same prosody but novel syllables, e.g., producing “breastfed” like “brastfid”). This evidence for an independent word-level prosodic representation, which has been hard to detect in previous studies, highlights the usefulness of sensorimotor adaptation as a tool for language production research.
Transition ability to safe states reduces fear responses to height
Authors: Haruno Masahiko , Fujino Misako
Published: December 2024

Previous studies on fear extinction have primarily focused on repeated exposure to fear-inducing context without negative consequences. However, it is also possible that an individual can reduce fear responses by predicting that they can transition to a safe environment through their own actions, even if a fear-inducing context appears. The effect of this transition ability on fear responses remains largely unexplored. Here, by conducting virtual reality (VR) experiments involving height and flight scenarios, we examined whether participants' fear responses to height decrease after actively experiencing a low-altitude VR flight, which allowed them to predict that they would be in a safe state by flying even if they fell from a height. Specifically, participants in the flight group (n=49) flew over a city at altitudes below 5 meters for 7 minutes, while participants in the control group (n=50) watched a video of a flight group participant's experience. Before and after the flight or passive viewing task, both groups walked on a plank while having their skin conductance response (SCR) and subjective fear score (SFS) measured. We found that the active flight group exhibited a greater reduction in both SCR and SFS compared to the control group, and that the questionnaire score of the controllability over the virtual self-body during the VR flight, predicts the SCR reduction in the flight group. These results clarified that the ability to transition to safe states by self actions can reduce physiological and subjective fear responses.
Design and Evaluation of Dental and Oral Health Education Using Design Thinking
Authors: Blolong Damiana Trivinita L , Wibowo Merlinda
Published: December 2024

Purpose: To design a learning  for dental and oral health by applying the Design thinking method.Design/method/approach: using the Design thinking method which has several processes such as Empathize, Define, Ideate, Prototype, and Test.Finding/Result:  Design as a learning media for dental and oral health that is adapted to what is needed by users.Originality/state of the art: Designing a learning media website using the design thinking method and then evaluating to measure the quality of the system using the System Usability Scale method.
Classification of apple maturity based on color using the K-Nearest Neighboor (KNN) method
Authors: Fa Nur , Saputra Rizal Adi , Nangi Jumadil
Published: December 2024

Purpose: The aim of this research is to provide support to apple fans and farmers in determining the choice of fruit that is ripe and ready to be consumed, using indicators of outer skin color as a basis for classification.Design/methodology/approach: The approach uses the K-Nearest Neighbor (KNN) method to classify the level of ripeness of apples based on skin color. KNN is used as a classification method. This approach utilizes the similarity of skin color with training data to determine the level of maturity. The evaluation results showed an accuracy of 90%, making it an effective approach for identifying the ripeness level of apples.Findings/result: From the results of the system evaluation of 206, it shows an accuracy level of 90% with a sensitivity of 80% and a specificity of 67% as measured by the Hold Out Estimation model.Originality/value/state of the art: This research uses test data/testing data originating from Kaggle and Google as well as several photos taken directly. In total, 206 images of apples were used.
The Application of Artificial Intelligence in Waste Classification as an Effort In Plastic Waste Management
Authors: Listyalina Latifah , Utami Ratri Retno , Arifin Uma Fadzilia , Putri Naimah
Published: December 2024

Purpose: Sorting waste before it is deposited in the Final Disposal Site (TPA) is crucial to reduce the increasing amount of waste accumulation each year. This issue can be addressed by implementing machines capable of automatically sorting waste.Design/methodology/approach: This research is quantitative and utilizes secondary data, namely image data of various types of waste. The images will be classified into organic and inorganic waste using a deep learning model. The measurement conducted involves assessing the accuracy of the designed deep learning model in classifying waste images into appropriate categories.Fondings/results: Based on the available dataset, waste identification will be performed, including food waste, paper, wood, leaves, electronic waste, metal, plastic, and bottles. The overall accuracy of the model is 94.42%, indicating that the model correctly classifies 94.42% of waste samples.Originality/value/state of the art: This research can classify 8 types of waste classes successfully using deep learning.
Application of the Technological Acceptance Model(TAM) Approach to the Influence of Public Perceptions Using Digital Wallets
Authors: Saputra Elin Panca , Saputro Achmat Yulyadi , Priyono Priyono , Kusumo Aryo Tunjung , Rahman Taufik
Published: December 2024

Purpose: This research aims to conduct a study of the perceptions of digital wallet users and how users' reactions influence the benefits of digital wallets in the big city of JakartaDesign/methodology/approach: The research method applied is a quantitative method. The population of this research is digital wallet users in the city of Jakarta. The number of samples applied was 121 respondents according to the purposeful sampling method. The data testing methods applied are convergent validity, discriminant validity, composite reliability and Cronbanch alpha. Data calculations apply Smart PLS 3 software. The results of this study show that trust and perceived risk do not influence user preferences for using digital walletsFindings/result: The results of this research constantly support a number of previous studies related to TAM where perceived usefulness and perceived ease of use play a direct and indirect role in interest in using digital wallets. So the community's perceived usefulness is a variable that has a prominent influence on the preferences of digital wallet users in the city of Jakarta.Originality/value/state of the art: The steps taken from the start of the study to its conclusion were designed to use the TAM approach to determine how the public felt about this particular study. This study uses quantitative research methods and yields two models: an inner model, or structural model, that includes path analysis through Smart PLS 3 data analysis, and an outer model, or measurement model, that includes composite reliability, conbranch alpha, discriminant validity, and convergent validity.
Tahsin Tracker as an Effort to Improve the Services of the Islamic Studies Development Institute for Lecturers and Education Personnel at Ahmad Dahlan University
Authors: Tarmuji Ali , Masduki Yusron
Published: December 2024

Purpose: This research aims to produce a Tahsin Tracker application as a tool to overcome several problems in managing tahsin guidance organized by the Islamic Studies and Development Institute (LPSI) UAD for lecturers and education staff.Design/method/approach: The method used in system development by applying general software development methods. The stages adopted include data collection, needs analysis (user and system), design (process, database and interface), implementation (database and program, and system testing.Results: A Mobile Web-based Tahsin Tracker application has been produced and has been tested on potential users using black box and SUS testing. Black box testing is 100% valid. The SUS test obtained a score of 79. Based on the SUS score of 79, the application is in the Acceptance Range: ACCEPTABLE, Grade Scale: C, and Adjective Rating: EXCELLENT category.Originality/state of the art: Based on previous research, as well as the results of the development of existing tahsin applications, this research adopts and complements existing deficiencies and produces new assessments of the features and usability in related units, because it replaces the manual method of book record basis, and becomes the main alternative for developing institutional service media in a better direction.
Performance Analysis of FastAPI Framework on Lost Circulation Handling Management Application in Oil Well Drilling
Authors: Suryotomo Andiko Putro , Akbar Bagus Muhammad , Husaini Rochmat
Published: December 2024

Purpose: This study aims to conduct a load testing using JMeter and then analyze the performance of the FastAPI framework on the backend of the lost circulation handling management application in oil well drilling. The developed API receives input in the form of drilling parameter data (daily drilling report) from drilling engineers to be processed by a machine learning model (prediction and classification) through the FastAPI framework. The developed API returns processing data in JSON format.Methodology: Performance measurement is done by conducting load testing simulations using the help of JMeter software. Load testing scenarios are created by varying the number of users and ramp-up time, as well as the method of loading the machine learning model used (normal or preemptive loading). The parameters measured in the test scenario are average execution time, maximum execution time, error percentage, and request throughput.Findings: Load testing on a FastAPI-developed API demonstrated that for compute-heavy tasks like machine learning inference, increasing the number of processor cores and using preemptive model loading led to significantly better performance improvements than changes in processor clock speed or switching from HDD to SSD. Even when simulating a higher user load than initially expected (up to 250 users/threads), FastAPI maintained good response times and a low error rate, remaining below 20%.Originality/value/state of the art: This study result is an information about the performance of the FastAPI framework in the application of lost circulation handling management in oil well drilling in the deployment phase, not only up to the model testing phase as in previous studies.
Forecasting Sea Surface Salinity in the Eastern Madura Strait Using a 1D Convolutional Neural Network
Authors: Rozzy Fahrul , Novitasari Dian Candra Rini , Yuliati Dian , Sani Puteri Permata
Published: December 2024

Tujuan: Penelitian ini bertujuan untuk memprediksi salinitas permukaan air laut pada perairan Selat Madura bagian Timur menggunakan 1D CNN dan menguji daripada performa model arsitektur 1D CNN yang dibuat. Berdasarkan hasil prediksi yang diperoleh, diharapkan mampu memberi informasi ke masyarakat terkait kondisi salinitas permukaan Selat Madura bagian Timur beberapa hari ke depan.Perancangan/metode/pendekatan: Hal pertama yang perlu dilakukan adalah memprediksi tiap parameter sebelum memprediksi salinitas permukaan. Penelitian ini menggunakan metode 1D CNN, dengan parameter kecepatan arus eastward, arus northward dengan 3 kedalaman berbeda, dan salinitas pada 2 kedalaman berbeda.Hasil: Berdasarkan penelitian ini diperoleh model 1D CNN mampu memprediksi salinitas dengan sangat baik, dengan MAPE sebesar 2.86% pada nilai dropout 0.8 dan batchsize 64. Adapun hasil prediksi untuk 6 hari ke depan, dari 17 Januari 2023 pukul 19.00 hingga 23 Januari 2023 pukul 07.00 dengan rentang waktu per 12 jam adalah mengalami penurunan dengan angka terendah menyentuh 33.313 PSU.Keaslian/ state of the art: Pada penelitian ini menggunakan parameter prediksi, metode, dan diperoleh hasil yang berbeda dengan penelitian sebelumnya.
التسلح ومعضلة الأمن في المنطقة المغاربية: التنافس الجزائري - المغربي
Authors: بن عنتر عبد النور
Published: December 2024

تتناول الدراسة مسألة التسلح ومعضلة الأمن في المنطقة المغاربية، مع التركيز على التنافس بين الجزائر والمغرب. وتجادل بأن مستوى تسلح البلدين ارتفع على نحو ملحوظ في السنوات الأخيرة، في سياق تنافس بنيوي؛ ما جعل المنطقة المغاربية واحدة من أكثر المناطق تسلحًًا في العالم، على الرغم من غياب التهديدات البينية الوجودية. تحاول الدراسة فحص مسألة التسلح في المنطقة المغاربية وفهم محدداتها وتطوراتها، مركّّزةًً على العوامل التي تؤثر فيها وتداعياتها المحتملة. وباعتماد المقاربة الواقعية إطارًًا نظريًًا، تتناول الدراسة عدة محاور، منها تحليل بيانات معهد ستوكهولم للسلام لإظهار حجم الإنفاق العسكري المغاربي المرتفع وتطوره، وتحليل محددات التسلح المغاربي ومخاطره العسكرية. وتُُختم باستنتاجات أساسية منها أن: تسلّّح البلدين يعكس تنافسهما على الزعامة ومدركات التهديد، وأن دينامية التسلح مستقلة عن التوترات السياسية البينية، وأن ثمة احتمال مواجهة عسكرية بين القوتين الإقليميتين بسبب تفاعل عوامل طارئة وأخرى بنيوية.
سياسة الردع والدول المراجِِعة من منظور واقعي: أزمة سد النهضة نموذجًًا
Authors: فكري مروة
Published: December 2024

تناقش هذه الدراسة القدرة التفسيرية للمدرسة الواقعية لأزمة سد النهضة بين كل من مصر وإثيوبيا، انطلاقًًا من مقولات نظريتي الردع، وتحدي الدول المراجعة للمهيمن. وتعتمد على مفهوم الهيمنة بمعناه الواسع الذي يشمل الهيمنة المائية، حيث يكون سلوك إثيوبيا سلوكًًا مراجعًًا للهيمنة المصرية في حوض النيل. وتخلص الدراسة إلى أن أزمة سد النهضة تبرز نجاحات المنظور الواقعي وإخفاقاته؛ فهي تعكس من ناحية الأفكار الواقعية الخاصة بأهمية عنصر القوة وبناء التحالفات، وفكرة تضارب المصالح والمكاسب النسبية وأثر النظام الدولي في سلوك الدول. ومن ناحية أخرى، تبرز قصور الواقعية في التفسير نتيجة إهمالها العوامل الداخلية وأهمية العوامل غير المادية في تحقيق مصالح الدولة وتفعيل هيمنتها.
من مرحلة ما بعد الديمقراطية إلى مرحلة الديمقراطية الجديدة
Authors: صوفي نهيلة
Published: December 2024

عنوان الكتاب في لغته: From Post-democracy to Neo-democracy.
عنوان الكتاب: من مرحلة ما بعد الديمقراطية إلى مرحلة الديمقراطية الجديدة.
تأليف: كلاوس فون بايمه.
ترجمة: سيد فارس.
الناشر: الدوحة/ بيروت: المركز العربي للأبحاث ودراسة السياسات.
سنة النشر: 2017
In vitro Assessment of Paclitaxel-loaded Niosome Nanoparticles and Their Cytotoxic Effects on the Ovarian Cancer Cell Line A2780CP
Authors: Khaje Nasrin , Salehan Fatemeh , Shakiba Davoud , Shabestari Aida Mohammadiun , Shoarishoar Seyedeh Shahed
Published: December 2024

Background: One of the major concerns in contemporary medical science is the issue of cancer, with ovarian cancer being a significant contributor to cancer-related deaths. A key challenge in treating ovarian cancer is its initial responsiveness followed by resistance to paclitaxel therapy. However, recent advances in nanotechnology, particularly drug delivery systems like niosomes, offer promising solutions.
Methods: Researchers fabricated nanoparticles via the ether injection approach and analyzed them for particle dimensions, surface charge, and medication release characteristics. Subsequently, they employed A2780CP ovarian cancer cell lines to evaluate the impact of nanodrug using an MTT assay.
Results: The average particle size was reported at 190.3 ± 20.6 nm, with a zeta potential of -18.9 ± 2.7 mV. Notably, high encapsulation proficiency (87.6 ± 32%) verified the successfulness of the applied technique. Moreover, the cytotoxicity assessment demonstrated enhanced efficacy of nanodrug over free carboplatin when targeting A2780CP cell lines (P < 0.05).
Conclusion: these findings suggest that pegylated liposomal nanocarriers could be effective carriers for delivering paclitaxel to A2780CP ovarian cancer cell lines.
Histopathological Spectrum of Gastroduodenal Biopsies in North East India - A 1 Year Cross-sectional Study in a Tertiary Care Centre
Authors: Sarma Usha , Kalita Upasana
Published: December 2024

Background: Gastrointestinal problems are very common nowadays and most people are likely to experience gastrointestinal symptoms throughout their lives. Acid peptic disease (APD), including gastric ulcers, duodenal ulcers, and gastro esophageal reflux disease is a common disorder of the gastrointestinal region, the pathogenesis of which involves an imbalance between acid secretion and gastric mucosal defenses. Besides, malignancies are also fairly common in these regions. This is a study done in 100 cases of gastroduodenal biopsies in a 1 year period.
Aims and Objectives: To see the histopathological spectrum of gastro-duodenal biopsy tissue collected by endoscopy and to correlate the association with clinical and demographic findings.
Result: The prevalence of gastroduodenal lesion is more common among males around the fifth decade of life. Abdominal pain and dyspepsia were the most common presenting clinical complaint. There were 56 benign cases, 11 cases of premalignant category (Dysplasia/ Metaplasia) and 27 malignant cases, out of which Moderately differentiated Adenocarcinoma was the most common.
Conclusion: Endoscopic gastroduodenal biopsies helps in detecting benign as well as malignant lesions. A variety of non-neoplastic and neoplastic lesions were reported in the present study across a wide range of age and site distribution. The combination of endoscopy and histopathological study of gastroduodenal biopsy provide a powerful diagnostic tool for better management of patients.
The Association of Helicobacter pylori Infection and Virulence Factors in Gastric Cancer in Thi-Qar, Iraq
Authors: Qasim Maytham T. , Mohammed Zainab I.
Published: December 2024

Background: The significance of Helicobacter pylori (H. pylori) infection in developing gastric cancer has been increasingly recognized. However, a noticeable gap exists in the literature regarding the prevalence of key virulence factors, particularly in Iraq. Therefore, Our study aimed to investigate the prevalence of H. pylori infection and the presence of virulence factors, namely the CagA and VacA genes, in gastric cancer patients.
Methods: A case-control study was conducted on 45 gastric cancer patients (38 males and 7 females) from September 2020 to February 2021. During routine endoscopic procedures, gastric biopsy specimens were collected from the tumour and adjacent non-tumour tissues. The presence of H. pylori was detected using quantitative real-time PCR, and the virulence factors CagA and vacA were identified using specific primers.
Results: H. pylori infection was detected in a significant 85% (38/45) of the patients, with a higher prevalence in males 89.5% (34/38) compared to females 10.5% (4/38) (P=0.021) (Chi-square test). No significant age-related differences were observed. The CagA gene was present in a substantial 58.8% (22/38) of H. pylori-positive patients, predominantly in tumor tissues at 81.81% (18/22), while the vacA gene was found in only one patient. These results underscore the importance of our research in understanding the prevalence of H. pylori infection and the presence of virulence factors in gastric cancer patients.
Conclusion: The high prevalence of H. pylori infection and the significant presence of the CagA virulence factor in tumour tissues underscore the bacterium’s role and risk factors in gastric carcinogenesis in Thi-Qar, Iraq.
Ameliorative Potential of Ursolic Acid Isolated from Morina coulteriana Royle Targeting P53 Gene Mutation Induced by Cyclophosphamide
Authors: Kour Jasbir , Lone Bashir Ahmad , Shah Naseer ue-din , Ganai Bashir A. , Ali Md.  Niamat , Akbar Seema
Published: December 2024

Objective: More than 50% of human cancers show mutated TP53 gene. Reactivation or restoration of p53 mutations is viewed as a potential approach for treating cancer. The objective of the present study was to determine whether ursolic acid (UA) could effectively restore the p53 mutations to their wild type or normal state and upregulate its expression.
Methods: The animals were divided into 3 groups, each with 10 mice. Group I was the negative control which received normal saline with 1% dimethyl sulfoxide (DMSO). Group II was the positive control which received cyclophosphamide (CP) (50mg/kg bw) intrapritonealy for 4 days continuously after which the animals were kept on normal saline for the rest 10 days. The treatment group received cyclophosphamide (CP) initially for the first 4 successive days intraperitoneally (50mg/kg bw) and then ursolic acid (UA) (60 mg/kg bw) orally for the next 10 days (post-treatment). Isolated DNA was used in Sanger sequencing of the polymerase chain reaction (PCR) amplified product of the TP53 gene.
Results: Our study demonstrated that UA treatment post CP injection had a restoration efficacy of 89.08%. The molecule, in this investigation, was able to restore the wild type (normal) conformation to the mutations induced by cyclophosphamide in the TP53 gene. 89.08 % mutations converted back to their normal or wild-type forms in the treatment group.
Conclusion: Several investigations have been carried out on this molecule and have indicated UA as a promising chemopreventive agent. The most frequently mutated gene in any type of cancer is the tumor suppressor p53 and UA has shown a potential in functional restoration of the mutated p53 protein. p53 is known to play a vital role in apoptosis and the p53 dependent apoptotic pathway is of prime importance in cancer therapy. Though there has been pioneering work on PRIMA-1 and thiosemicarbazones, identification and development of additional molecules is required.
Enhancing the Cytotoxic Effects of Carboplatin and Cisplatin on Liposomes in Oral Cancer Cells with Curcumin
Authors: Saeidi Nastaran , Ansarikojouri Mandana , Mardani Maryam , Rezazadeh Reza , Khanlari Goodarzi Mahyar , Amiri Faezeh
Published: December 2024

Background: Oral squamous cell carcinoma remains challenging to treat effectively with conventional chemotherapy, leading researchers to explore synergistic combinations to enhance therapeutic outcomes. Combining curcumin with platinum-based drugs, such as cisplatin and carboplatin, has demonstrated potential in enhancing cytotoxic effects. However, limited studies have explored these combinations’ efficacy and sustained release profile in liposomal form specifically for oral cancer. This study investigates the enhanced cytotoxic effects of cisplatin-curcumin and carboplatin-curcumin nanoliposome formulations on CAL 27 oral cancer cells.
Methods and Materials: Nanoliposomes encapsulating cisplatin or carboplatin with curcumin were formulated and characterized by particle size, zeta potential, and polydispersity index (PDI) to ensure optimized delivery properties. Particle sizes of the cisplatin and carboplatin nanoliposomes ranged from 175 to 187 nm, with a zeta potential greater than -30 mV, indicating good stability, and PDI values less than 0.48, suggesting uniform particle size distribution. In vitro cytotoxicity was assessed using the MTT assay at 24, 48, and 96 hours across different curcumin concentrations.
Results: Cisplatin-curcumin and carboplatin-curcumin nanoliposome formulations demonstrated significantly increased cytotoxicity in CAL 27 cells compared to control groups. Drug release studies indicated a sustained release profile, with approximately 22% of cisplatin and 28% of carboplatin released over 52 hours, which may prolong therapeutic effects by maintaining drug availability within the cancer cells.
Conclusion: The findings suggest that cisplatin-curcumin and carboplatin-curcumin nanoliposomal formulations enhance the cytotoxic effects of these chemotherapeutic agents while providing a stable, sustained release profile.
Unveiling the Anticarcinogenic Efficacy of Nirgundi with Emphasis on Oral Cancer: A Comprehensive Review
Authors: Ravi Ashwini , V Vasanthi , K B Vinitha , Padmanabhan Gopikrishna , Venkatkumar Shruthi , K Rajkumar
Published: December 2024

India contributes one-third to the global cancer burden, which may be attributed to the fact that the diagnosis is usually made in the advanced stage. Oral cancer is the most common cancer, predominantly caused by the use of tobacco in middle-aged males in India. The concept of chemotherapy initially emerged after systemic mustard gas poisoning damaged the bone marrow and lymphatic tissues. Traditional medicine has been proven to have medicinal value with fewer side effects as compared to allopathic drugs. Phytochemicals have been reported to exert anticancer effects by modulating the immune response and targeting the molecular mechanisms. Few studies have demonstrated that the traditional herbs exert antitumor efficacy by inducing cytotoxicity, promoting apoptosis, regulating epigenetic modifications, inhibiting metastasis along with their antioxidant and anti-inflammatory activity. Nirgundi (Vitex negundo) in various composition has been used in producing commercial pharmaceutical products for the management of both oral health and general health. The present review focuses on the antitumorigenic efficacy of Nirgundi in various cancers, with an emphasis on oral cancer.
Perception and Belief of Dietary Intake among Newly Diagnosed with Gynaecologic Cancer in Malaysia: A Qualitative Study
Authors: Yi Ho Chiou , Mat Daud Zulfitri Azuan , Mohd Yusof Barakatun Nisak , Abdul Majid Hazreen
Published: December 2024

Background: Gynaecologic cancers (GC) experience unintentional weight loss and inadequate oral intake even before treatment. Cancer patients are at risk of accessing inaccurate advice and misleading information due to the prevalence of misinformation regarding nutrition and cancer in the media. This study aimed to obtain a comprehensive understanding of the perception and belief of dietary intake among newly diagnosed with GC in Malaysia.
Methods: We conducted in-depth qualitative interviews with 12 GC respondents from three major ethnicities and continued until the saturation point was reached. A semi-structured interview guide is employed. The interviews were audio recorded and verbally transcribed. Thematic analysis with theoretical saturation was applied to data analysis.
Results: The majority of patients interviewed reported that they made dietary modifications following their GC diagnosis, such as healthy eating, and began taking supplements. Their belief and perception of dietary intake were influenced by the impact of diagnosis, uncertainty, and fear of cancer progression and empowerment through nutrition. The cultural influence and access to resources and information might affect their dietary intake. There was evidence of navigating information overload from various sources after newly diagnosed GC. They felt a dilemma in food choices, balancing emotional and nutritional needs. The multidisciplinary support systems and healthcare delivery approach were useful.
Discussion and conclusion: The perception and belief of dietary intake among newly diagnosed with GC in Malaysia is diverse and can vary greatly depending on individual experiences, beliefs, and situations. They may attempt to restore some control over their health in the face of a cancer diagnosis. All respondents admitted that they changed to a healthy diet after being diagnosed with GC. The healthcare profession might benefit from current qualitative research to better understand more patients and increase the quality of oncology dietetic service and decision-making. Hence, effective dietary interventions and support strategies could be established for this population.
The Therapeutic Implications of Biomarkers Testing in Non-small Cell Lung Cancer in Middle- and Low-income Country: The Example of Morocco
Authors: Aazzane Oussama , Fathi Sofia , Meryem Charkaoui , Abdelkader Acharki , Souha Sahraoui , Nadia Benchakroun , Hassan Fellah , Mehdi Karkouri
Published: December 2024

Introduction: The Identification of PD-L1, EGFR and ALK status is essential to guide personalized treatment of NSCLC. The objective of our study is to evaluate the implication of changing the therapeutic protocol on the prognosis of Moroccan patients with NSCLC.
Methods: Between January 2019 and February 2023, 96 patients with NSCLC were recruited.
Results: In our population, the patients were treated with different first-line protocols: 83.34% (N=80) with neo-adjuvant chemotherapy, 14.58% (N=14) with immunotherapy and 2.08% (N=2) with targeted therapy. Of the 82 patients who received neo-adjuvant chemotherapy (N=80), 24 were able to switch to immunotherapy. While, the 2 patients who received targeted therapy beforehand also switched to immunotherapy. The influence of the number of chemotherapy (Chemo) cycles on vital status and overall survival (OS) of the 24 patients who switched from their initial protocol to immunotherapy (IO) showed that patients who received IO after completing the 4 or 5 cycles of chemo had a good OS, with a mean of 29.07 months. In comparison, patients who received less than 4 cycles of chemo had a mean OS of 14.70 months, while those who received more than 5 cycles of chemo had a mean OS of 21.38 months. Furthermore, the association between change in treatment protocol and patient vital status was significant (p=0.013). However, there was a significant difference in OS between patients who maintained the treatment protocol (mean OS=12.43 months) and those who changed the protocol (mean OS=24.01 months) (p=0.000). Multivariate analysis indicated that maintaining the initial therapeutic protocol was independently associated with a reduced OS (p=0.003).
Conclusion: Our results highlight the impact of changing the protocol on the OS of NSCLC patients taking into account the importance of choosing the right timing to switch to IO based on the number of prior chemo cures.
العلاقة بين الحرية الأكاديمية والتفكير الإيجابي لدى أعضاء الهيئة التدريسية في الجامعات الفلسطينية
Authors: رمضان جهاد عبد الفتاح , قدومي عبد الناصر عبدالرحيم
Published: December 2024

الأهداف: هدفت الدراسة التعرف إلى العلاقة بين الحرية الأكاديمية والتفكير الإيجابي لدى أعضاء الهيئة التدريسية في الجامعات الفلسطينية، والفروق فيهما تبعًا لمتغير الرتبة الأكاديمية. المنهجية: لتحقيق أهداف الدّراسة استخدم المنهج الوصفي التحليلي نظرًا لملاءمته لأهداف الدراسة، وأجريت الدراسة على عينة عشوائية-طبقية مكونة من (420) من أعضاء الهيئة التدريسية في الجامعات الفلسطينية وتمثل ما نسبته (10%) تقريبًا من مجتمع الدراسة. ولجمع البيانات استخدم مقياسين الأول مقياس الحرية الأكاديمية (12) فقرة، والآخر مقياس التفكير الإيجابي (11) فقرة. النتائج: توصلت الدراسة إلى أن مستوى الحرية الأكاديمية لدى أعضاء الهيئة التدريسية في الجامعات الفلسطينية كان مرتفعًا أما مستوى التفكير الإيجابي فجاء مرتفعًا جدًا، ووجود علاقة إيجابية بين الحرية الأكاديمية والتفكير الإيجابي لدى أعضاء الهيئة التدريسية في الجامعات الفلسطينية في الضفة الغربية. الخلاصة: في ضوء نتائج الدّراسة، أوصى الباحثان بتعزيز سياسات الحرية الأكاديمية لجميع أعضاء الهيئة التدريسية، بغض النظر عن الرتبة الأكاديمية، بحيث يمكن تحقيق ذلك من خلال تنظيم ورش عمل وبرامج تدريبية تهدف إلى تعزيز الوعي بأهمية الحرية الأكاديمية وأثرها الإيجابي على التفكير الإيجابي والإبداع الأكاديمي.
تمويل التعليم العام في المملكة العربية السعودية في ضوء خبرات بعض الدول المتقدمة
Authors: السيف عواطف , الجريسي أماني , السعيد هديل
Published: December 2024

الأهداف: هدفت الدراسة الحالية إلى التعرف على واقع مويل التعليم العام في المملكة العربية السعودية والتعرف على واقع تمويل التعليم العام في عدد من الدول المتقدمة منها: فنلندا واليابان والولايات المتحدة. المنهجية: استخدم المنهج الوصفي التحليلي القائم على جمع وتحليل المعلومات التي تضمنتها أدبيات الدراسات السابقة المتعلقة بتمويل التعليم للمقارنة بين الدول. الخلاصة: توصلت الدراسة إلى عدد من التوصيات أهمها: تعيين كوادر وطنية مؤهلة وعلى درجه عالية من الاحترافية لإدارة الموارد المالية، وضع خطة استراتيجية لتنويع مصادر التمويل الذاتي في المدارس، الاستفادة من تجارب الدول المتقدمة في بعض مصادر التمويل والحث على تطبيق نموذج المدرسة المنتجة في المدارس.
معتقدات طلبة التأهيل التربوي بجامعة نزوى في توظيف أدوات الذكاء الاصطناعي في العملية التعليمية بسلطنة عُمان
Authors: الندابي عزيز بن سيف بن محمد , الرواحي منصور بن ياسر بن عبيد
Published: December 2024

الأهداف: هدفت الدراسة إلى التعرف على معتقدات طلبة التأهيل التربوي بجامعة نزوى في توظيف أدوات الذكاء الاصطناعي في العملية التعليمية. المنهجية: اتبعت الدراسة المنهج المسحي القائم على استبانة لقياس معتقدات الطلبة، وتمثلت عينة الدراسة بمجموع (187) طالب وطالبة من مختلف التخصصات الإنسانية والتطبيقية تم اختيارها بطريقة عشوائية. النتائج: توصلت الدراسة إلى وجود معتقدات مرتفعة لدى طلبة التأهيل التربوي في استخدام أدوات الذكاء الاصطناعي في العملية التعليمية، كما أظهرت النتائج عدم وجود فروق دالو إحصائيًا معتقدات توظيف أدوات الذكاء الاصطناعي في العملية التعليمية لدى طلبة دبلوم التأهيل التربوي بجامعة نزوى تبعًا لمتغير نوع التخصص (إنساني/ علمي). الخلاصة: قدمت الدراسة عددًا من التوصيات بناء على نتائجها منها: دعم طلبة التأهيل التربوي وتعزيز ممارساتهم التدريسية في توظيف أدوات الذكاء الاصطناعي، وتوفير البيئة التعليمية الرقمية اللازمة لتطبيق تقنيات الذكاء الاصطناعي في التدريس.
العلاقة بين الروح الرياضية والهوية الرياضية لدى لاعبي الكرة الطائرة في فلسطين
Authors: قدومي عبد الناصر عبدالرحيم , يوسف حسين محمد , سالم جمال شاكر
Published: December 2024

الأهداف: هدفت الدراسة التعرف إلى درجة الروح الرياضية والهوية الرياضية والعلاقة بينهما لدى لاعبي الكرة الطائرة في فلسطين. المنهجية: استخدم المنهج الوصفي الارتباطي نظرًا لملاءمته لأهداف الدراسة، وتكونت العينة من (114) لاعبًا من أندية الدرجة الممتازة والأولى للكرة الطائرة في فلسطين، وطبق مقياس روبرت وآخرون Robert,etal,1997) ( للروح الرياضية، ومقياس بروور وكورلنز (Brewer and Cornelius, 2001) للهوية الرياضية. النتائج: توصلت نتائج الدراسة إلى أن درجة الروح الرياضية كانت كبيرة وبوزن نسبي (84%)، ودرجة الهوية الرياضية كبيرة جدًا وبوزن نسبي (85.42%)، وكانت العلاقة بين الروح الرياضية والهوية الرياضية إيجابية، حيث وصل معامل الارتباط بيرسون بينهما إلى (0.73) والانحدار إلى (0.534). الخلاصة: أوصت الدراسة بعدة توصيات من أهمها: زيادة اهتمام المدربين بتضمين التدريبات والمواقف التدريبية المشابهة لطبيعة الأداء في البرامج التدريبية التي تسهم في تنمية كل من الروح الرياضية والهوية الرياضية عند الإعداد النفسي والتربوي والمعرفي للاعبين.
درجة ممارسة القيادة الابتكارية وعلاقتها بالفاعلية التنظيمية لدى مديري مدارس التعليم الأساسي في سلطنة عُمان
Authors: العامرية بدرية بنت حمود بن سعيد
Published: December 2024

الأهداف: هدفت الدراسة الحالية تعرف درجة ممارسة مديري المدارس للقيادة الابتكارية وعلاقتها بالفاعلية التنظيمية في مدارس التعليم الأساسي (5-10) بمحافظتَيْ مسقط والداخلية. المنهجية: لتحقيق أهداف الدراسة الحالية تَمَّ استخدام المنهج الوصفي الارتباطي، كما اسْتُخْدِمَتِ الاستبانة أداةً للدراسة الحالية في جمعِ البيانات والمعلومات، وتَمَّ التَّأَكُّد من صدقها وثباتها، وطُبِّقَتْ على عيِّنة مكوَّنة من (474) معلِّمًا ومُعَلِّمَةً في مدارس التعليم الأساسي (5-10) بمحافظتَيْ مسقط والداخلية في سلطنة عُمَان. النتائج: من أَهَمِّ النتائج التي توصَّلت إليها الدراسة الحالية هي: إِنَّ درجة ممارسة القيادة الابتكارية لدى مديري مدارس التعليم الأساسي بمحافظتَيْ مسقط والداخلية في سلطنة عُمَان جاءت بدرجة ممارسة كبيرة، كما كشفت نتائج الدراسة الحالية أَنَّ درجة الفاعلية التنظيمية في مدارس التعليم الأساسي من الصفوف (5-10) في محافظتَيْ مسقط والداخلية في سلطنة عُمَان جاءت بمستوًى كبير، كذلك كشفت نتائج الدراسة الحالية وجود علاقة ارتباطية موجبة ودالة إحصاءً بين أبعاد القيادة الابتكارية جميعها لمديري المدارس وأبعاد الفاعلية التنظيمية لمدارس الحلقة الثانية في محافظتَيْ مسقط والداخلية بسلطنة عُمَان. الخلاصة: في ضوء ما توصَّلَتْ إليه الدراسة الحالية من نتائج؛ تَمَّ تقديم مجموعة من التوصيات أَبْرَزُها: تنفيذ المزيد من الدورات والبرامج التدريبية التي تُعْنَى بتنمية مستوى ممارسة مديري المدارس للقيادة الابتكارية، والعمل على مراجعة استراتيجيَّات تقويم مديري المدارس؛ بحيث تشتمل على المزيد من البنود التي تهتمُّ بتقييم درجة ممارسة مديري المدارس للقيادة الابتكارية، وأثرها في الفاعلية التنظيمية بالمدرسة.
Opportunities and Challenges of Online Professional Development Training: Perspectives of Private Schools’ Teachers
Authors: Abuhattab Sobhi Yousef , Arafeh Ali Jamal , Alghafri Mohammed Suloom
Published: December 2024

Objectives: This study aimed to explore the perspectives of English Language teachers in private Schools regarding opportunities and challenges of online professional development (PD) programs. It also investigated their attitudes towards these online programs. Methods: The qualitative method was employed to provide in-depth insights into the complex and nuanced perspectives of teachers regarding online professional development (PD), 5 Semi structured focus group interviews were conducted via Zoom platform with a subset of English Language teachers (N=20) randomly selected from a total of 100 male and female English Language teachers in 6 private international schools at Ajman Educational Zone. The interview main questions and follow up ones were validated by a jury of experts. Inter-rater reliability was also conducted to ensure the accuracy and precision of the results analysis. In addition, two research main questions were used to guide the study. Results: The results showed that Online Professional Development Programs granted teachers professional development training opportunities in terms of quality and quantity as well as types and varieties since these programs are flexible, and affordable. They could also save time, efforts, money, and energy. In contrast, the challenges lied in language barriers, and appropriateness for the specific needs of teachers, students, subjects, and context. Additionally, most teachers developed positive attitudes towards online professional development programs. Conclusion: It could be concluded that online professional development training programs were beneficial for teachers who developed mostly positive attitudes in various aspects like flexibility, affordability and variations though there were some barriers like appropriateness and language barriers.
Orality and Literature. On the Genealogy of Modern Culture in Friedrich Nietzsche's Basel Lectures
Authors: Santini Carlotta
Published: December 2024

The lectures on classical philology that Friedrich Nietzsche delivered in Basel between 1869 and 1879 constitute an extraordinarily promising new field of study that has opened up in recent years to Nietzsche scholars. In this article I intend to offer a novel reconstruction of Greek culture as it emerges from Nietzsche's Lectures on the History of Greek Literature. In a pioneering manner with respect to his time, Nietzsche identifies the dimension of orality, of the spoken word, as the salient character of Greek culture, and he sets it against contemporary culture and education, which are based on writing and learning from books. My purpose is to show how Nietzsche's cultural critique acts, taking its cue from an ancient and obsolete culture to highlight the weaknesses and contradictions of his contemporary culture.
Kant’s Project of the “Metaphysics of Morals” in Systematic and Historical Contexts
Authors: Terletsky Vitali
Published: December 2024

Kant first publicized the concept of “metaphysics of morals” in the Critique of Pure Reason and further justified it in other works. However, we can state some distinctive features and perspectives of this project. There are reasons to single out three meanings of this concept: the entire project of pure moral philosophy (MM1), the late work with the same name Metaphysics of Morals (1797) (MM2), the chapter in Groundwork (1785) on “Transition from popular moral philosophy to the metaphysics of morals” (MM3). It is obvious that MM2 and MM3 belong to MM1 as a whole systematic project of the metaphysics of morals. Among Kant scholars was established the view that Kant’s project of “metaphysics of morals” was “completely new”, and the concept itself is Kant’s “creature” (G. Tonelli, R. Brandt). Instead, recent research shows that this project belongs to the modern tradition of universal ethics (Pufendorf, Wolff and his school).
Dmytro Chyzhevskyi, Semen Semkovskyi according to criminal case dated December 16, 1920
Authors: Davidenko Illia
Published: December 2024

In 1920, Dmytro Chyzhevsky and Semen Semkovsky were defendants in a criminal case opened as part of the Bolshevik struggle against the Menshevik opposition. The author describes for the first time a number of documents from this case and compares it with the materials of some modern studies. Since Chyzhevskyi and Semkovskyi later became leaders of “emigrant” and “mainland” Ukrainian philosophy respectively, the author proves that the empirical material he describes cannot be ignored in a theoretical understanding of what Ukrainian philosophy was in the 1920s and 1930s.
Soviet Philosophy and Expertise: One Episode from Volodymyr Shynkaruk
Authors: Skrypnyk Kateryna
Published: December 2024

The first annotated publication of Volodymyr Shynkarukʼs expert opinion (prepared in 1984) on the script for the film “Five Spoons of Elixirˮ by the Strugatsky brothers.
Zinaida Luzina: White Spots on the Map of the Philosophy of the «Executed Renaissance» Era
Authors: Shvets Ryenat
Published: December 2024

The first commented edition of the text of Zinaida Luzina’s Curriculum vitae autograph, based on the material of her academic files as well as other documents and periodicals of the 1920s and 1930s.
Medieval thought from a fresh perspective. Arlig, A. W. (2023). Medieval Philosophy: A Contemporary Introduction. New York: Routledge.
Authors: Shymanovych Andrii
Published: December 2024

Review of Arlig, A. W. (2023). Medieval Philosophy: A Contemporary Introduction. New York: Routledge.
To hold Power over Being and Essence. Cassin, B., & Sigov, C. (2024). European dictionary of philosophies: Ukrainian context. Lexicon of untranslatables. Chapters V-VI (Vol. V, pp. 179-198). Kyiv: Duh i Litera.
Authors: Tekliuk Anatolii
Published: December 2024

Review of Chapters V “State and Power” and VI “Being and Essence” from Volume V of the European Dictionary of Philosophy (Kyiv: Duh i Litera, 2024).
Review of 2023 Papers on the History of Philosophy in the Journal “Filosofska Dumkaˮ
Authors: Holovashenko Iryna
Published: December 2024

An overview of papers devoted to the history of philosophy in the journal “Filosofska dumkaˮ (Philosophical Thought) (2023).
To the Origins of Modern Moral Philosophy. Darwall, S. L. (2023). Modern moral philosophy: from Grotius to Kant. Cambridge, & New York: Cambridge University Press.
Authors: Khoma Vsevolod
Published: December 2024

Review of Darwall, S. L. (2023). Modern moral philosophy: from Grotius to Kant. Cambridge, & New York: Cambridge University Press.
Archivum Sententiarum: the First Results
Authors: Davidenko Illia
Published: December 2024

Report on the first half of the year of the academic-archival center for the study of the history of Ukrainian philosophy of the 20th century Archivum Sententiarum.
Microvascular decompression in trigeminal neuralgia using a robot-assisted exoscope and head-mounted display
Authors: Rossini Zefferino , Tropeano Maria Pia , Franzini Andrea , Bresciani Ettore , Doneddu Pietro Emiliano , Pensato Umberto , Pessina Federico
Published: December 2024

OBJECTIVE

Microvascular decompression (MVD) in trigeminal neuralgia (TN) is currently managed using an operating microscope (OM). Recent experiences with endoscopy-assisted, fully endoscopic, and exoscopic surgery have been described, aiming to improve ergonomics and image quality. The aim of this study was to report the first series of patients operated on with the aid of a robotic binocular exoscope using a head-mounted display (RoboticScope).

METHODS

From September 2023 to March 2024, 9 patients with TN were treated using the RoboticScope. A classic mini-retrosigmoid approach was performed and standard microsurgical techniques were applied. Surgical timing, ergonomics, visual performances, adverse events, and 1-month postoperative pain outcomes were evaluated.

RESULTS

All surgeries were completed without shifting to the OM. Surgeon comfort with the RoboticScope was better compared with the OM and visualization was good. No intraoperative adverse events were recorded. The duration of the procedure was significantly shorter with the RoboticScope compared to those using the OM (median 18 vs 34 minutes, p = 0.0001).

CONCLUSIONS

MVD can be safely and effectively performed using the RoboticScope. Surgeons benefit from better ergonomics, stereoscopic image quality, and shorter surgical duration.