bluuebunny/crossref_metadata_2025 huggingface dataset:
Non-Toxin-Based Clostridioides difficile Vaccination Approaches
Authors: Razim Agnieszka , Górska Sabina , Gamian Andrzej
Published: February 2023

Clostridioides difficile (CD) is a Gram-positive, anaerobic bacterium that infects mainly hospitalized and elderly people who have been treated with long-term antibiotic therapy leading to dysbiosis. The deteriorating demographic structure and the increase in the number of antibiotics used indicate that the problem of CD infections (CDI) will continue to increase. Thus far, there is no vaccine against CD on the market. Unfortunately, clinical trials conducted using the CD toxin-based antigens did not show sufficiently high efficacy, because they did not prevent colonization and transmission between patients. It seems that the vaccine should also include antigens found in the bacterium itself or its spores in order not only to fight the effects of toxins but also to prevent the colonization of the patient. This literature review summarizes the latest advances in research into vaccine antigens that do not contain CD toxins.
Efficient Development of Green Emulsifier/Emollient-Based Emulsion Vehicles: From RSM Optimal Experimental Design to Abridged In Vivo Assessment
Authors: Vukašinović Mila , Savić Sanela , Cekić Nebojša , Ilić Tanja , Pantelić Ivana , Savić Snežana D.
Published: February 2023

Since natural-origin, sustainable ingredients are preferred by modern consumers, novel emulsifiers and emollients keep entering the market. This study hypothesizes that a combination of in silico, instrumental tools and simplified sensory studies could be used to efficiently characterize emulsions in a shorter timeframe. A total of 22 rather simple o/w emulsions were prepared by a time/energy-saving emulsification process. A natural mixed emulsifier (Lauryl Glucoside/Myristyl Glucoside/Polyglyceryl-6 Laurate) and two emollients (both with INCI name C15–19 Alkane) were used. The performed D-optimal experimental design within the response surface method (RSM) significantly narrowed down the number of samples about to enter the stage of texture, friction and sensory studies to the samples comprising 30% of a respective Emogreen emollient and 2% or 3% of the emulsifier. The sample comprising 2% emulsifier/30% Emogreen® L15 showed significantly higher firmness (42.12 mN) when compared to the one with 2% emulsifier/30% Emogreen® L19 (33.62 mN), which was somewhat unexpected considering the emollients’ inherent viscosity values (4.5 mPa·s for L15 and 9 mPa·s for L19). The sample with 2% emulsifier/30% Emogreen® L19 managed to maintain the lowest friction, while the one with 3% emulsifier/30% Emogreen® L19 released its full lubricating potential in the second part of the measurement (30–60 s). The obtained results revealed the strengths and weaknesses of each formulation, narrowing down their possible applications in the early development stage.
Acceleration of Wound Healing through Amorphous Calcium Carbonate, Stabilized with High-Energy Polyphosphate
Authors: Wang Shunfeng , Neufurth Meik , Schepler Hadrian , Tan Rongwei , She Zhending , Al-Nawas Bilal , Wang Xiaohong , Schröder Heinz C. , Müller Werner E. G.
Published: February 2023

Amorphous calcium carbonate (ACC), precipitated in the presence of inorganic polyphosphate (polyP), has shown promise as a material for bone regeneration due to its morphogenetic and metabolic energy (ATP)-delivering properties. The latter activity of the polyP-stabilized ACC (“ACC∙PP”) particles is associated with the enzymatic degradation of polyP, resulting in the transformation of ACC into crystalline polymorphs. In a novel approach, stimulated by these results, it was examined whether “ACC∙PP” also promotes the healing of skin injuries, especially chronic wounds. In in vitro experiments, “ACC∙PP” significantly stimulated the migration of endothelial cells, both in tube formation and scratch assays (by 2- to 3-fold). Support came from ex vivo experiments showing increased cell outgrowth in human skin explants. The transformation of ACC into insoluble calcite was suppressed by protein/serum being present in wound fluid. The results were confirmed in vivo in studies on normal (C57BL/6) and diabetic (db/db) mice. Topical administration of “ACC∙PP” significantly accelerated the rate of re-epithelialization, particularly in delayed healing wounds in diabetic mice (day 7: 1.5-fold; and day 13: 1.9-fold), in parallel with increased formation/maturation of granulation tissue. The results suggest that administration of “ACC∙PP” opens a new strategy to improve ATP-dependent wound healing, particularly in chronic wounds.
Novel Regioselective Synthesis of 1,3,4,5-Tetrasubstituted Pyrazoles and Biochemical Valuation on F1FO-ATPase and Mitochondrial Permeability Transition Pore Formation
Authors: Algieri Vincenzo , Algieri Cristina , Costanzo Paola , Fiorani Giulia , Jiritano Antonio , Olivito Fabrizio , Tallarida Matteo Antonio , Trombetti Fabiana , Maiuolo Loredana , De Nino Antonio , Nesci Salvatore
Published: February 2023

An efficient, eco-compatible, and very cheap method for the construction of fully substituted pyrazoles (Pzs) via eliminative nitrilimine-alkene 1,3-dipolar cycloaddition (ENAC) reaction was developed in excellent yield and high regioselectivity. Enaminones and nitrilimines generated in situ were selected as dipolarophiles and dipoles, respectively. A deep screening of the employed base, solvent, and temperature was carried out to optimize reaction conditions. Recycling tests of ionic liquid were performed, furnishing efficient performance until six cycles. Finally, a plausible mechanism of cycloaddition was proposed. Then, the effect of three different structures of Pzs was evaluated on the F1FO-ATPase activity and mitochondrial permeability transition pore (mPTP) opening. The Pz derivatives’ titration curves of 6a, 6h, and 6o on the F1FO-ATPase showed a reduced activity of 86%, 35%, and 31%, respectively. Enzyme inhibition analysis depicted an uncompetitive mechanism with the typical formation of the tertiary complex enzyme-substrate-inhibitor (ESI). The dissociation constant of the ESI complex (Ki’) in the presence of the 6a had a lower order of magnitude than other Pzs. The pyrazole core might set the specific mechanism of inhibition with the F1FO-ATPase, whereas specific functional groups of Pzs might modulate the binding affinity. The mPTP opening decreased in Pz-treated mitochondria and the Pzs’ inhibitory effect on the mPTP was concentration-dependent with 6a and 6o. Indeed, the mPTP was more efficiently blocked with 0.1 mM 6a than with 1 mM 6a. On the contrary, 1 mM 6o had stronger desensitization of mPTP formation than 0.1 mM 6o. The F1FO-ATPase is a target of Pzs blocking mPTP formation.
Endophytic Fungi Isolated from Ageratina adenophora Exhibits Potential Antimicrobial Activity against Multidrug-Resistant Staphylococcus aureus
Authors: Wen Juan , Okyere Samuel Kumi , Wang Jianchen , Huang Ruya , Wang Ya , Liu Lin , Nong Xiang , Hu Yanchun
Published: February 2023

Multidrug-resistant bacteria such as Staphylococcus aureus (MRSA) cause infections that are difficult to treat globally, even with current available antibiotics. Therefore, there is an urgent need to search for novel antibiotics to tackle this problem. Endophytes are a potential source of novel bioactive compounds; however, the harnessing of novel pharmacological compounds from endophytes is infinite. Therefore, this study was designed to identify endophytic fungi (from Ageratina adenophora) with antibacterial activity against multidrug-resistant bacteria. Using fungal morphology and ITS-rDNA, endophytic fungi with antibacterial activities were isolated from A. adenophora. The results of the ITS rDNA sequence analysis showed that a total of 124 morphotype strains were identified. In addition, Species richness (S, 52), Margalef index (D/, 7.3337), Shannon–Wiener index (H/,3.6745), and Simpson’s diversity index (D, 0.9304) showed that A. adenophora have abundant endophytic fungi resources. Furthermore, the results of the agar well diffusion showed that the Penicillium sclerotigenum, Diaporthe kochmanii, and Pestalotiopsis trachycarpicola endophytic fungi’s ethyl acetate extracts showed moderate antibacterial and bactericidal activities, against methicillin-resistant Staphylococcus aureus (MRSA) SMU3194, with a MIC of 0.5–1 mg/mL and a MBC of 1–2 mg/mL. In summary, A. adenophora contains endophytic fungi resources that can be pharmacologically utilized, especially as antibacterial drugs.
Plant Peroxisomal Polyamine Oxidase: A Ubiquitous Enzyme Involved in Abiotic Stress Tolerance
Authors: Samanta Ishita , Roy Pamela Chanda , Das Eshani , Mishra Sasmita , Chowdhary Gopal
Published: February 2023

Polyamines (PAs) are positively charged amines that are present in all organisms. In addition to their functions specific to growth and development, they are involved in responding to various biotic and abiotic stress tolerance functions. The appropriate concentration of PA in the cell is maintained by a delicate balance between the catabolism and anabolism of PAs, which is primarily driven by two enzymes, namely diamine oxidase and polyamine oxidase (PAO). PAOs have been found to be localized in multiple subcellular locations, including peroxisomes. This paper presents a holistic account of peroxisomal PAOs. PAOs are flavin adenine dinucleotide-dependent enzymes with varying degrees of substrate specificity. They are expressed differentially upon various abiotic stress conditions, namely heat, cold, salinity, and dehydration. It has also been observed that in a particular species, the various PAO isoforms are expressed differentially with a spatial and temporal distinction. PAOs are targeted to peroxisome via a peroxisomal targeting signal (PTS) type 1. We conducted an extensive bioinformatics analysis of PTS1s present in various peroxisomal PAOs and present a consensus peroxisome targeting signal present in PAOs. Furthermore, we also propose an evolutionary perspective of peroxisomal PAOs. PAOs localized in plant peroxisomes are of potential importance in abiotic stress tolerance since peroxisomes are one of the nodal centers of reactive oxygen species (ROS) homeostasis and an increase in ROS is a major indicator of the plant being in stress conditions; hence, in the future, PAO enzymes could be used as a key candidate for generating abiotic stress tolerant crops.
Assessment of the Effect of Treating ‘GiSelA 5’ Softwood Cuttings with Biostimulants and Synthetic Auxin on Their Root Formation and Some of Their Physiological Parameters
Authors: Świerczyński Sławomir
Published: February 2023

The ‘GiSelA 5’ rootstock is of high importance for growing sweet cherries because it significantly reduces the growth vigour of the trees and accelerates their fruiting. However, the method of its propagation using ‘in vitro’ cultures is expensive, prompting researchers to look for alternative methods of propagation. One of these is the root formation in shoot cuttings. The experiment presented in this paper compared the use of powdered synthetic auxins (Rhizopon AA, Ukorzeniacz AB) and their alcoholic solution (IAA, IBA), and the biostimulants Goteo and Bispeed as foliar sprays for root formation in softwood cuttings ‘GiSelA 5’ and measured some parameters of physiological processes. In addition, two different substrates of river sand with peat (1:2) and peat substrate with perlite (2:1) were used. Cuttings were obtained on two dates, in the first and third years in the month of June. Biostimulants increased the number of rooted cuttings (Goteo—16.1%, Bispeed—18.1%) without improving their growth and the intensity of most of the analyzed physiological processes compared to the control. Synthetic preparations also increased the percentage of rooted cuttings Rhizopon AA (24.4%), Ukorzeniacz AB (21.4%), auxin IBA (19.7%) and auxin IAA (14.7%), while simultaneously improving their growth and level of vital processes compared to the controls and biostimulants. The substrate consisting of peat with sand improved root formation by 6.2%, without significantly changing the growth parameters and vital functions of the cuttings. The earlier date of propagation increased the root formation percentage only by 4% and the number of roots by 14% of the ‘GiSelA 5’ rootstock cuttings.
Public Health Implications of Invasive Plants: A Scientometric Study
Authors: Denóbile Camila , Chiba de Castro Wagner Antonio , Silva Matos Dalva Maria da
Published: February 2023

Movements of organisms through distinct places can change the dynamics of ecological interactions and make the habitat conducive to the spread of diseases. Faced with a cyclical scenario of invasions and threats in a One Health context, we conducted a scientometric study to understand how disturbances in environments with invaded vegetation affect the incidence of parasites and disease prevalence rates. The search was carried out in Web of Science and Scopus databases, with keywords delimited by Boolean operators and based on the PRISMA protocol. Thirty-sixarticles were full-read to clarify the interaction between diseases and invaded areas. The analysis covered publications from 2005 to 2022, with a considerable increase in the last ten years and a significant participation of the USA on the world stage. Trends were found in scientific activities, and we explored how invasive species can indirectly damage health, as higher concentrations of pathogens, vectors, and hosts were related to structurally altered communities. This paper reveals invaded plants threats that enhance disease transmission risks. It is likely that, with frequent growth in the number of introduced species worldwide due to environmental disturbances and human interventions, the negative implications will be intensified in the coming years.
Phytotoxicity of Quillaja lancifolia Leaf Saponins and Their Bioherbicide Potential
Authors: Marques Maria E. M. , de Carvalho Ana C. , Yendo Anna C. A. , Magedans Yve V. S. , Zachert Eliane , Fett-Neto Arthur G.
Published: February 2023

Weeds are major threats to the integrity of agricultural and natural environments due to their invasive and competing potential. Bioherbicides are substances based on natural compounds that are biodegradable and often have low residual effects. Plant species able to produce and release phytotoxic compounds may represent effective bioherbicide sources. Leaves of Quillaja lancifolia D.Don (formerly Q. brasiliensis (A.St.-Hil. & Tul.) Mart.) produce water-soluble specialized metabolites of the saponin class that could be evaluated for phytotoxic activity and potential as natural herbicides. This study was conducted to examine the impacts of Q. lancifolia total saponins aqueous extract (AE) at 4 and 10% (w/v) and of two combined reverse-phase chromatography purified saponin fractions (QB) at 1 and 2% (w/v) on morpho-physiological parameters of Lactuca sativa (lettuce) and Echinochloa crus-galli (barnyardgrass) in pre- and post-emergence bioassays. QB was only tested in pre-emergence assays. In pre-emergence bioassays, the germination rate and germination kinetics were determined. Post-emergence evaluations included effects on seedling morphology, root and shoot length, dry mass, and chlorophyll content. Osmotic potential and pH analyses ruled out roles for these factors in the observed responses. AE had a high inhibitory impact on the germination of both lettuce and barnyardgrass. QB at 1% and 2% (w/v) significantly decreased the growth of lettuce seedlings germinated in its presence by more than 10-fold. Phytotoxic effects on the post-emergence growth of lettuce, especially at the highest concentration tested of AE (10% w/v), was also observed. The presence of quillaic acid-based triterpene saponins in AE and QB was confirmed using different analytical methods. Therefore, both saponin-enriched fraction and aqueous extracts of Q. lancifolia inhibited tested plant growth and development. The water solubility of saponins and the availability of a sustainable source of these molecules from the leaves of cultivated young Q. lancifolia plants make them attractive candidates for use as bioherbicides.
Ozone and Temperature May Hinder Adaptive Capacity of Mediterranean Perennial Grasses to Future Global Change Scenarios
Authors: Prieto-Benítez Samuel , Ruiz-Checa Raquel , González-Fernández Ignacio , Elvira Susana , Rucandio Isabel , Alonso Rocío , Bermejo-Bermejo Victoria
Published: February 2023

Climate warming is recognized as a factor that threatens plant species in Mediterranean mountains. Tropospheric ozone (O3) should also be considered as another relevant stress factor for these ecosystems since current levels chronically exceed thresholds for plant protection in these areas. The main aim of the present study was to study the sensitivity of four Mediterranean perennial grasses to O3 and temperature based on plant growth, gas exchange parameters (photosynthesis—A, stomatal conductance—gs, and water use efficiency—WUE), and foliar macro- (N, K, Ca, Mg, P, and S) and micronutrients (B, Cu, Fe, Mn, Mo, and Zn) content. The selected species were grasses inhabiting different Mediterranean habitats from mountain-top to semi-arid grasslands. Plants were exposed to four O3 treatments in Open-Top chambers, ranging from preindustrial to above ambient levels, representing predicted future levels. Chamber-less plots were considered to study the effect of temperature increase. Despite the general tolerance of the grasses to O3 and temperature in terms of biomass growth, WUE and foliar nutrient composition were the most affected parameters. The grass species studied showed some degree of similarity in their response to temperature, more related with phylogeny than to their tolerance to drought. In some species, O3 or temperature stress resulted in low A or WUE, which can potentially hinder plant tolerance to climate change. The relationship between O3 and temperature effects on foliar nutrient composition and plant responses in terms of vegetative growth, A, gs, and WUE constitute a complex web of interactions that merits further study. In conclusion, both O3 and temperature might be modifying the adaptation capacity of Mediterranean perennial grass species to the global change. Air pollution should be considered among the driving favors of biodiversity changes in Mediterranean grassland habitats.
Copolymerization of Carbon Dioxide with 1,2-Butylene Oxide and Terpolymerization with Various Epoxides for Tailorable Properties
Authors: Tang Shuo , Suo Hongyi , Qu Rui , Tang Hao , Sun Miao , Qin Yusheng
Published: February 2023

The copolymerization of carbon dioxide (CO2) with epoxides demonstrates promise as a new synthetic method for low-carbon polymer materials, such as aliphatic polycarbonate materials. In this study, a binary Schiff base cobalt system was successfully used to catalyze the copolymerization of 1,2-butylene oxide (BO) and CO2 and its terpolymerization with other epoxides such as propylene oxide (PO) and cyclohexene oxide (CHO). 1H nuclear magnetic resonance (1H NMR), diffusion-ordered spectroscopy (DOSY), gel permeation chromatography (GPC), and differential scanning calorimetry (DSC) confirmed the successful synthesis of the alternating terpolymer. In addition, the effects of the polymerization reaction conditions and copolymerization monomer composition on the polymer structure and properties were examined systematically. By regulating the epoxide feed ratio, polycarbonates with an adjustable glass transition temperature (Tg) (11.2–67.8 °C) and hydrophilicity (water contact angle: 85.2–95.2°) were prepared. Thus, this ternary polymerization method provides an effective method of modulating the surface hydrophobicity of CO2-based polymers and their biodegradation properties.
Study on the Influence of Accelerated Aging on the Properties of an RTV Anti-Pollution Flashover Coating
Authors: Chen Junwei , Li Bo , Zeng Xiaomei , Li Zhenggang , Wen Yi , Hu Quan , Yang Qiu , Zhou Mi , Yang Bing
Published: February 2023

The purpose of this work is to study the accelerated aging behavior of a room-temperature vulcanized (RTV) silicone rubber anti-pollution flashover coating. Red, blue and gray RTV rubber samples were selected to prepare coatings on the surface of stainless-steel sheets. The accelerated aging test was carried out in an aging test chamber according to a four-step program cycle. After the completion of different aging tests, the color difference, glossiness, surface micromorphology, wettability, insulation performance and other parameters of the samples were measured using colorimetry, infrared spectrometry, scanning electron microscopy, and a high-voltage breakdown tester. The results showed that with the increase in aging time, the color difference ∆Eab of the coatings increased. The G60 gloss value decreased gradually and tended to be saturated after 60 cycles. After the aging tests, the RTV coating surface had holes, cracks, peeling and other damage to varying degrees. The C:Si atomic ratio was less than 2, and the hydrophobicity was obviously deteriorated. After aging, the electrical strength of the three RTV coatings decreased significantly. It can be concluded that during the accelerated aging test, the RTV coating had cross-linking and oxidation reactions, and the internal deterioration and surface damage of the coating led to changes in its color, luster, morphology, insulation strength, etc.
Structural, Mechanical, and Tribological Properties of Oriented Ultra-High Molecular Weight Polyethylene/Graphene Nanoplates/Polyaniline Films
Authors: Dayyoub Tarek , Maksimkin Aleksey , Olifirov Leonid K. , Chukov Dilus , Kolesnikov Evgeniy , Kaloshkin Sergey D. , Telyshev Dmitry V.
Published: February 2023

Preparing high-strength polymeric materials using an orientation drawing process is considered one of the most urgent topics in the modern world. Graphene nanoplates/polyaniline (GNP/PANI) were added to the commercial grade UHMWPE (GUR 4120) matrix as a filler with antifriction properties. The effect of GNP/PANI addition on the structure, the orientation process, the void formation (cavitation), the mechanical, and tribological properties was studied using differential scanning calorimetry (DSC), dynamical mechanical analysis (DMA), and scanning electron microscopy (SEM). The paper’s findings indicated an increase in the cavitation effect of 120–320% after the addition of GNP/PANI to the UHMWPE polymer matrix. This increase, during the process of the oriented films’ thermal orientation hardening, led, in turn, to a decrease in the tensile strength during the process of the oriented films’ thermal orientation hardening. Furthermore, the decrease in the coefficient of friction in the best samples of oriented UHMWPE films was two times greater, and the increase in wear resistance was more than an order of magnitude. This process was part of the orientation hardening process for the UHMWPE films containing PE-wax as an intermolecular lubricant, as well as the presence of GNP/PANI in the material, which have a high resistance to abrasive wear.
Development of Photoluminescent and Photochromic Polyester Nanocomposite Reinforced with Electrospun Glass Nanofibers
Authors: Abdu Mahmoud T. , Khattab Tawfik A. , Abdelrahman Maiada S.
Published: February 2023

A polyester resin was strengthened with electrospun glass nanofibers to create long-lasting photochromic and photoluminescent products, such as smart windows and concrete, as well as anti-counterfeiting patterns. A transparent glass@polyester (GLS@PET) sheet was created by physically immobilizing lanthanide-doped aluminate (LA) nanoparticles (NPs). The spectral analysis using the CIE Lab and luminescence revealed that the transparent GLS@PET samples turned green under ultraviolet light and greenish-yellow in the dark. The detected photochromism can be quickly reversed in the photoluminescent GLS@PET hybrids at low concentrations of LANPs. Conversely, the GLS@PET substrates with the highest phosphor concentrations exhibited sustained luminosity with slow reversibility. Transmission electron microscopic analysis (TEM) and scanning electron microscopy (SEM) were utilized to examine the morphological features of lanthanide-doped aluminate nanoparticles (LANPs) and glass nanofibers to display diameters of 7–15 nm and 90–140 nm, respectively. SEM, energy-dispersive X-ray spectroscopy (EDXA), and X-ray fluorescence (XRF) were used to analyze the luminous GLS@PET substrates for their morphology and elemental composition. The glass nanofibers were reinforced into the polyester resin as a roughening agent to improve its mechanical properties. Scratch resistance was found to be significantly increased in the created photoluminescent GLS@PET substrates when compared with the LANPs-free substrate. When excited at 368 nm, the observed photoluminescence spectra showed an emission peak at 518 nm. The results demonstrated improved hydrophobicity and UV blocking properties in the luminescent colorless GLS@PET hybrids.
Paving the Way for Synthetic Intrinsically Disordered Polymers for Soft Robotics
Authors: Coskuner-Weber Orkid , Yuce-Erarslan Elif , Uversky Vladimir N.
Published: February 2023

Nature is full of examples of processes that, through evolution, have been perfected over the ages to effectively use matter and sustain life. Here, we present our strategies for designing intrinsically disordered smart polymers for soft robotics applications that are bio-inspired by intrinsically disordered proteins. Bio-inspired intrinsically disordered smart and soft polymers designed using our deep understanding of intrinsically disordered proteins have the potential to open new avenues in soft robotics. Together with other desirable traits, such as robustness, dynamic self-organization, and self-healing abilities, these systems possess ideal characteristics that human-made formations strive for but often fail to achieve. Our main aim is to develop materials for soft robotics applications bio-inspired by intrinsically disordered proteins to address what we see as the largest current barriers in the practical deployment of future soft robotics in various areas, including defense. Much of the current literature has focused on the de novo synthesis of tailor-made polymers to perform specific functions. With bio-inspired polymers, the complexity of protein folding mechanisms has limited the ability of researchers to reliably engineer specific structures. Unlike existing studies, our work is focused on utilizing the high flexibility of intrinsically disordered proteins and their self-organization characteristics using synthetic quasi-foldamers.
A Reactive Molecular Dynamics Study on Crosslinked Epoxy Resin Decomposition under High Electric Field and Thermal Aging Conditions
Authors: Sun Wei-Feng , Chern Wen Kwang , Chan John Chok You , Chen Zhong
Published: February 2023

To reveal the microscopic mechanism of synergetic thermal–electrical degradation during a partial discharge process in epoxy insulation materials, the decomposition of crosslinked epoxy resin is investigated using reactive molecular dynamics simulations under high electric field and thermal degradation conditions. Bond-boost acceleration method is employed in reactive molecular dynamics simulations to successfully establish epoxy polymer models with a crosslink degree of 93%. Active molecular species derived from electrical partial discharges are considered in the current work. Small molecule products and decomposition temperature in the degradation process under an electric field are calculated to elucidate the effect of nitric acid and ozone molecules, being the active products generated by electrical partial discharges, on the synergetic thermal–electrical degradation of epoxy resin. Both nitric acid and ozone exacerbate thermal impact decomposition of crosslinked epoxy polymer by decreasing initial decomposition temperature from 1050 K to 940 K and 820 K, respectively. It is found that these active products can oxidize hydroxyl groups and carbon–nitrogen bridge bonds in epoxy molecular chains, leading to the aggravation of epoxy resin decomposition, as manifested by the significant increase in the decomposed molecular products. In contrast, thermal degradation of the epoxy resin without the active species is not expedited by increasing electric field. These strongly oxidative molecules are easily reduced to negative ions and able to obtain kinetic energies from electric field, which result in chemical corrosion and local temperature increase to accelerate decomposition of epoxy insulation materials.
Adsorptive Removal of Boron by DIAION™ CRB05: Characterization, Kinetics, Isotherm, and Optimization by Response Surface Methodology
Authors: Al-dhawi Baker , Kutty Shamsul , Hayder Gasim , Elnaim Bushra , Mnzool Mohammed , Noor Azmatullah , Saeed Anwar , Al-Mahbashi Najib , Al-Nini Ahmed , Jagaba Ahmad
Published: February 2023

A significant issue for the ecosystem is the presence of boron in water resources, particularly in produced water. Batch and dynamic experiments were used in this research to extract boron in the form of boric acid from aqueous solutions using boron selective resins, DIAION CRB05. DIAION™ CRB05 is an adsorbent that is effective in extracting boron from aqueous solutions due to its high binding capacity and selectivity for boron ions, and it is also regenerable, making it cost-effective and sustainable. Field Emission Scanning Electron Microscopy (FESEM), X-ray diffraction (XRD), and FTIR analysis for DIAION CRB05 characterization. To increase the adsorption capacity and find the ideal values for predictor variables such as pH, adsorbent dose, time, and boric acid concentration, the Box–Behnken response surface method (RSM) was applied. The dosage was reported to be 2000 mg/L at pH 2 and boron initial concentration of 1115 mg/L with 255 min for the highest removal anticipated from RSM. According to the outcomes of this research, the DIAION CRB05 material enhanced boron removal capability and has superior performance to several currently available adsorbents, which makes it suitable for use as an adsorbent for removing boric acid from aqueous solutions. The outcomes of isotherm and kinetic experiments were fitted using linear methods. The Temkin isotherm and the pseudo-first-order model were found to have good fits after comparison with R2 of 0.998, and 0.997, respectively. The results of the study demonstrate the effectiveness of DIAION™ CRB05 in removing boron from aqueous solutions and provide insight into the optimal conditions for the adsorption process. Thus, the DIAION CRB05 resin was chosen as the ideal choice for recovering boron from an aqueous solution because of its higher sorption capacity and percentage of boron absorbed.
Mechanical and Durability Properties of CCD-Optimised Fibre-Reinforced Self-Compacting Concrete
Authors: Sivanandam Gunachandrabose , Venkataraman Sreevidya
Published: February 2023

The accelerated advancement of industrialization, urbanization, and technology produces an enormous amount of waste materials that are channelled into the environment, contaminating the soil, water and air. This exceedingly large volume of waste in the planet’s environment has made it challenging and difficult to handle; thus, it is urgent to facilitate alternative methods of waste disposal. Moreover, the consumption of concrete raw materials increases as a consequence of a sudden increase in concrete usage. In this study, printed circuit boards (PCB), cutting waste (e-waste) (0%, 5%, 10%, 15%, 20%) and recycled concrete aggregate (construction and demolition waste) (0%, 20%, 40%, 60%, 80%, 100%) replace the fine and coarse aggregate; this is utilised in the making of self-compacting concrete (SCC). To mitigate the impact of shrinkage and micro-cracks produced during loading, synthetic fibres (polypropylene fibres) (0%, 0.25%, 0.5%, 0.75%, 1%) are incorporated into the dense matrix of concrete. Based on the experiments conducted, it is concluded that the optimum percentages of e-waste, recycled aggregate and synthetic fibres are 10%, 60% and 0.5%, respectively. It is proposed to use response surface methodology for the statistical modelling of fibre-reinforced self-compacting concrete (FRSCC) ingredients, which will diminish the number of experiments conducted during optimisation. Experimental optimisation of ingredients was carried out by determining the workability properties (slump flow, L-Box, V-Funnel and Sieve test), strength properties (compressive, split tensile, flexural at 7, 14, 28 days of curing) and durability properties against chemical exposure (sulphuric and hydrochloric acid attack, sulphate attack at 29 and 90 days of immersion). In the statistical optimisation process, the central composite design (CCD) is utilised, and it is concluded that the optimum percentages of e-waste, recycled aggregate and synthetic fibres are 9.90%, 51.35% and 0.503%, respectively, as these produce a compressive strength (CS) of 47.02 MPa at the end of the 28th day of curing, whereas FRSCC created with experimentally optimised ingredients shows a strength of 46.79 MPa with the use of 60% of recycled aggregate, 10% of e-waste and 0.5% polypropylene fibre. Hence, it is observed that the CCD-optimised ingredients were the optimum dosage of ingredients based on the compressive strength values at 28 days. It is concluded that the FRSCC specimens created with CCD-optimised parameters show better resistance against loading and chemical exposure, as these show minimum weight and strength loss when compared to FRSCC with experimentally optimised parameters.
Thermal and Sound Insulation Properties of Recycled Expanded Polystyrene Granule and Gypsum Composites
Authors: Bumanis Girts , Argalis Pauls Pavils , Sahmenko Genadijs , Mironovs Deniss , Rucevskis Sandris , Korjakins Aleksandrs , Bajare Diana
Published: February 2023

Up to now, primary resources have been the main choice of raw material selection for production. Now, global market tendencies have brought significant attention to secondary resources as the price has been raised for primary materials, and there is a shortage of their delivery. This could bring an additional effort to increase the recycling level of construction and demolition waste, including expanded polystyrene (EPS). Efforts have been made to develop new efficient building materials with a high content of recycled EPS. In this paper, composite insulation material made of gypsum hemihydrate and recycled EPS beads by casting and compression methods were evaluated, and properties were compared. Thermal and sound insulation properties were characterized. Density from 48 to 793 kg/m3 was obtained and the thermal conductivity coefficient from 0.039 to 0.246 W/(m·K) was measured. Compression strength was from 18 kPa to 2.5 MPa. Composites produced with the compression method have a sound absorption coefficient α > 0.9 in the range from 600 to 700 Hz, while the samples produced by casting showed poor sound absorption with wide deviation. Compression methods had an advantage over the casting method as more homogenous and lightweight materials were produced with improved insulation properties.
Contemporary Art and Sufi Aesthetics in European Contexts
Authors: Kuehn Sara
Published: February 2023

This article examines the work of seven contemporary artists whose aesthetics exemplify the “lived” experience of Islamic mysticism or Sufism (Arabic tasawwuf) within a European context. The work of artists born in Islamic majority countries and familiar with “traditional” Sufi idioms and discourses, but now immersed in Western culture, is often associated with “diasporic art”. From this hybrid perspective some of their artistic narratives reconfigure or even subvert the “traditional” Sufi idioms, and do so in such a way as to provoke a more profound sensory experience in the viewer than traditional forms of art. Drawing upon recent methodological tendencies inspired by the “aesthetic turn”, this study explores post- and decolonial ways of thinking about Sufi-inspired artworks, and the development of a transcultural Sufi-inspired aesthetic within the context of migration and displacement over the last half-century.
Palamism, Humboldtianism, and Magicism in Pavel Florensky’s Philosophy of Language
Authors: Biriukov Dmitry , Gravin Artyom
Published: February 2023

This article analyzes the evolution of Pavel Florensky’s teachings about language from the end of the 1910s to the early 1920s in the context of the two lines of influence (Humboldtian–Potebnian and Palamite) on the basis of which this teaching developed. In his reasoning about language, Florensky, proceeding from intuition, declares that there is a rigid connection between the word’s sound/phoneme; its morpheme, etymon, and sememe (the given here and now meaning); and its denotate. According to Florensky, this points to the magicism of the word as such. At the beginning of the 1910s, Florensky, having become a participant in the name-glorifying debates, also adhered to the line presupposing a rigid connection between the word’s sound (the name, which is applied to God), its meaning, and its denotate. All these lines converged in Florensky’s thoughts on the nature of language in the late 1910s and the early 1920s. He turned again to the Humboldtian–Potebnian language scheme but rethought it, speaking of the intentionally charged sememe as the word’s inner form. In texts written in the late 1910s and the early 1920s, we single out two aspects of the understanding of the magicism of the word which were key for Florensky, namely the aspect revealed in the discourse of the independent and autonomous existence of words and names and the aspect presupposing the intentionally willed moment in the phenomenon of the magicism of the word.
An Overhead Collapsible Origami-Based Mount for Medical Applications
Authors: Li Lailu , Long Flynn Loh Jian , Lim Irvin , Sun Tianyu , Ren Hongliang
Published: February 2023

To aid physicians in the precision diagnosis of ailments in the cranial region, we propose an overhead collapsible origami-based mount (Over-COM) with the advantages of being mountable, compact, lightweight, portable, and easy-to-use. The Over-COM can hold small diagnosis apparatuses, attach to regions of interest (ROIs) on the head, and adjust the posture and penetration angle of the sensor to detect the optimal medical signal. The prototype of the Over-COM consists of a setup (housing, eight linear actuators, and an IMU) that can be attached to the head with adhesive or straps, and a small box (containing the microcontroller and battery pack) that can be placed away from the patient. In order to verify the performance of the system, experiments investigating the device’s DOFs and scan protocols were carried out. The experimental results demonstrated that the Over-COM could hold the diagnosis device, locate the ROIs, and determine the best sensor posture and penetration angles.
A Review of Data Augmentation Methods of Remote Sensing Image Target Recognition
Authors: Hao Xuejie , Liu Lu , Yang Rongjin , Yin Lizeyan , Zhang Le , Li Xiuhong
Published: February 2023

In recent years, remote sensing target recognition algorithms based on deep learning technology have gradually become mainstream in the field of remote sensing because of the great improvements that have been made in the accuracy of image target recognition through the use of deep learning. In the research of remote sensing image target recognition based on deep learning, an insufficient number of research samples is often an encountered issue; too small a number of research samples will cause the phenomenon of an overfitting of the model. To solve this problem, data augmentation techniques have also been developed along with the popularity of deep learning, and many methods have been proposed. However, to date, there is no literature aimed at expounding and summarizing the current state of the research applied to data augmentation for remote sensing object recognition, which is the purpose of this article. First, based on the essential principles of data augmentation methods, the existing methods are divided into two categories: data-based data augmentation methods and network-based data augmentation methods. Second, this paper subdivides and compares each method category to show the advantages, disadvantages, and characteristics of each method. Finally, this paper discusses the limitations of the existing methods and points out future research directions for data augmentation methods.
Indoor Location Technology with High Accuracy Using Simple Visual Tags
Authors: Gao Feng , Ma Jie
Published: February 2023

To achieve low-cost and robustness, an indoor location system using simple visual tags is designed by comprehensively considering accuracy and computation complexity. Only the color and shape features are used for tag detection, by which both algorithm complexity and data storage requirement are reduced. To manage the nonunique problem caused by the simple tag features, a fast query and matching method is further presented by using the view field of the camera and the tag azimuth. Then, based on the relationship analysis between the spatial distribution of tags and location error, a pose and position estimation method using the weighted least square algorithm is designed and works together with the interactive algorithm by the designed switching strategy. By using the techniques presented, a favorable balance is achieved between the algorithm complexity and the location accuracy. The simulation and experiment results show that the proposed method can manage the singular problem of the overdetermined equations effectively and attenuate the negative effect of unfavorable label groups. Compared with the ultrawide band technology, the location error is reduced by more than 62%.
An Efficient Self-Organized Detection System for Algae
Authors: Gong Xingrui , Ma Chao , Sun Beili , Zhang Junyi
Published: February 2023

Algal blooms have seriously affected the production and life of people and real-time detection of algae in water samples is a powerful measure to prevent algal blooms. The traditional manual detection of algae with a microscope is extremely time-consuming. In recent years, although there have been many studies using deep learning to classify and detect algae, most of them have focused on the relatively simple task of algal classification. In addition, some existing algal detection studies not only use small datasets containing limited algal species, but also only prove that object detection algorithms can be applied to algal detection tasks. These studies cannot implement the real-time detection of algae and timely warning of algal blooms. Therefore, this paper proposes an efficient self-organized detection system for algae. Benefiting from this system, we propose an interactive method to generate the algal detection dataset containing 28,329 images, 562,512 bounding boxes and 54 genera. Then, based on this dataset, we not only explore and compare the performance of 10 different versions of state-of-the-art object detection algorithms for algal detection, but also tune the detection system we built to its optimum state. In practical application, the system not only has good algal detection results, but also can complete the scanning, photographing and detection of a 2 cm × 2 cm, 0.1 mL algal slide specimen within five minutes (the resolution is 0.25886 μm/pixel); such a task requires a well-trained algal expert to work continuously for more than three hours. The efficient algal self-organized detection system we built makes it possible to detect algae in real time. In the future, with the help of IoT, we can use various smart sensors, actuators and intelligent controllers to achieve real-time collection and wireless transmission of algal data, use the efficient algal self-organized detection system we built to implement real-time algal detection and upload the detection results to the cloud to realize timely warning of algal blooms.
3D Multi-Modality Medical Imaging: Combining Anatomical and Infrared Thermal Images for 3D Reconstruction
Authors: Abreu de Souza Mauren , Alka Cordeiro Daoana Carolaine , Oliveira Jonathan de , Oliveira Mateus Ferro Antunes de , Bonafini Beatriz Leandro
Published: February 2023

Medical thermography provides an overview of the human body with two-dimensional (2D) information that assists the identification of temperature changes, based on the analysis of surface distribution. However, this approach lacks spatial depth information, which can be enhanced by adding multiple images or three-dimensional (3D) systems. Therefore, the methodology applied for this paper generates a 3D point cloud (from thermal infrared images), a 3D geometry model (from CT images), and the segmented inner anatomical structures. Thus, the following computational processing was employed: Structure from Motion (SfM), image registration, and alignment (affine transformation) between the 3D models obtained to combine and unify them. This paper presents the 3D reconstruction and visualization of the respective geometry of the neck/bust and inner anatomical structures (thyroid, trachea, veins, and arteries). Additionally, it shows the whole 3D thermal geometry in different anatomical sections (i.e., coronal, sagittal, and axial), allowing it to be further examined by a medical team, improving pathological assessments. The generation of 3D thermal anatomy models allows for a combined visualization, i.e., functional and anatomical images of the neck region, achieving encouraging results. These 3D models bring correlation of the inner and outer regions, which could improve biomedical applications and future diagnosis with such a methodology.
A Perspective on Lifelong Open-Ended Learning Autonomy for Robotics through Cognitive Architectures
Authors: Romero Alejandro , Bellas Francisco , Duro Richard J.
Published: February 2023

This paper addresses the problem of achieving lifelong open-ended learning autonomy in robotics, and how different cognitive architectures provide functionalities that support it. To this end, we analyze a set of well-known cognitive architectures in the literature considering the different components they address and how they implement them. Among the main functionalities that are taken as relevant for lifelong open-ended learning autonomy are the fact that architectures must contemplate learning, and the availability of contextual memory systems, motivations or attention. Additionally, we try to establish which of them were actually applied to real robot scenarios. It transpires that in their current form, none of them are completely ready to address this challenge, but some of them do provide some indications on the paths to follow in some of the aspects they contemplate. It can be gleaned that for lifelong open-ended learning autonomy, motivational systems that allow finding domain-dependent goals from general internal drives, contextual long-term memory systems that all allow for associative learning and retrieval of knowledge, and robust learning systems would be the main components required. Nevertheless, other components, such as attention mechanisms or representation management systems, would greatly facilitate operation in complex domains.