bluuebunny/crossref_metadata_2025 huggingface dataset:
NARRATIVE TECHNOLOGY FOR THE DEVELOPMENT OF PERSONAL LIFE COMPETENCE
Authors:   G S. Kostiyk Institute of Psychology of the NAЕS of Ukraine, Rudnytska Svitlana
Published: October 2024

The article addresses the issue of developing personal life competence within the framework of the psychological-hermeneutic, specifically narrative, approach. The feasibility of using narrative technologies in the context of developing personal life competence is substantiated: by constructive problem-solving, effective setting and solving of life tasks, strengthening psychological resilience, enhancing self-awareness and reflection, and building productive adaptive strategies during the prolonged war in Ukraine. The article characterizes the author's narrative technology as "Core Personal Questions," aimed at developing personal life competence through self-reflection, defining personal values, motives, and goals, and forming a holistic self-image. The proposed technology helps individuals understand their own experiences, current resources, beliefs, behavioral strategies, self-presentations, and life and personal projects, which is of significant importance during the war. The narrative technology "Core Personal Questions" is directed towards constructing retrospective, current, and prospective self-narratives, through which the understanding of life and personal experiences, determination of meaningful priorities and prospects, and adaptation to the current crisis conditions occur. The use of this technology involves the development of personal life competence in three dimensions: routine-selective, adaptive, and innovative. The methodological tools are based on key questions, the search for answers to which fosters self-reflection, independent setting, clarification, and redefinition of the main life tasks by the individual. The article illustrates the possibilities of applying the proposed narrative technology in working with vulnerable populations during the war in Ukraine. Keywords: personality, life competence, development, dimensions of development, reflection, narrative, narrative technologies, personal questions, war in Ukraine
CORPORATE CULTURE AS A FACTOR IN PERSONNEL EFFICIENCY
Authors:   Taras Shevchenko National University of Kyiv, Chuhaieva Nataliia , Myshko Kseniia ,   National University of Food Technologies
Published: October 2024

The article is devoted to the study of the influence of corporate culture on the efficiency of personnel through the prism of work psychology. The main focus is on the analysis of key components of corporate culture, such as corporate values, norms and traditions, and their impact on staff motivation. Corporate culture is defined as a set of values and beliefs that determine the behavior of employees and the effectiveness of the organization as a whole. The psychological climate in the organization is considered as a critical factor affecting job satisfaction and the emotional state of employees. The article substantiates the importance of maintaining a healthy psychological climate for ensuring high productivity. Various aspects of personnel motivation are considered, including intrinsic and extrinsic incentives. It has been found that a positive corporate culture promotes motivation, improves communication and strengthens trust between employees. In particular, factors such as open communication, support from management and opportunities for professional development are key to ensuring high performance. The study shows that a positive psychological climate helps reduce stress levels and increase overall job satisfaction. It is noted that corporate values, which are shared by all members of the organization, create a basis for successful cooperation and achievement of common goals. The authors provide recommendations for implementing effective management practices to improve corporate culture. Special attention is paid to the role of leadership in the formation of a favorable working environment. The conclusions emphasize the need for a strategic approach to the formation of corporate culture. It is emphasized that investment in the development of corporate culture has a positive effect on the efficiency of the staff in general. Keywords: corporate culture, work psychology, personnel motivation, psychological climate, corporate values
Reproducible High Performance Computing without Redundancy with Nix
Authors: Goswami Rohit , S. Ruhila , Goswami Amrita , Goswami Sonaly , Goswami Debabrata
Published: October 2024

High performance computing (HPC) clusters are typically managed in arestrictive manner; the large user base makes cluster administrators unwillingto allow privilege escalation. Here we discuss existing methods of packagemanagement, including those which have been developed with scalability in mind,and enumerate the drawbacks and advantages of each management methodology. Wecontrast the paradigms of containerization via docker, virtualization via KVM,pod-infrastructures via Kubernetes, and specialized HPC packaging systems viaSpack and identify key areas of neglect. We demonstrate how functionalprogramming due to reliance on immutable states has been leveraged fordeterministic package management via the nix-language expressions. We show itsassociated ecosystem is a prime candidate for HPC package management. We furtherdevelop guidelines and identify bottlenecks in the existing structure andpresent the methodology by which the nix ecosystem should be developed furtheras an optimal tool for HPC package management. We assert that the caveats of thenix ecosystem can easily mitigated by considerations relevant only to HPCsystems, without compromising on functional methodology and features of thenix-language. We show that benefits of adoption in terms of generatingreproducible derivations in a secure manner allow for workflows to be scaled acrossheterogeneous clusters. In particular, from the implementation hurdles facedduring the compilation and running of the d-SEAMS scientific software engine,distributed as a nix-derivation on an HPC cluster, we identify communicationprotocols for working with SLURM and TORQUE user resource allocation queues.These protocols are heuristically defined and described in terms of thereference implementation required for queue-efficient nix builds.
Can electronic diary compliance yield information on cognitive control in remitted depressed- and never-depressed individuals? Insights from a multi-study analysis
Authors: Besten Marlijn Elisabeth , van Vugt Marieke K. , Yang Hang , Smit Arnout Christiaan , Aleman Andre , Riese Harriette , van Tol Marie-José
Published: October 2024

Major Depressive Disorder (MDD) is associated with cognitive control deficits that often persist after remission, affecting daily life functioning and increasing relapse risk. Residual symptoms such as negative affect and low motivation may impede cognitive control and thereby hamper goal directed behavior, and as such functioning in daily life. This study examined whether goal-directed behavior, for which we took compliance in responding to daily questionnaires in an experience sampling method (ESM) study as a proxy, 1) could reflect cognitive control allocation, 2) differs over time in individuals with remitted MDD compared to never-depressed (ND) individuals, and 3) relates to factors associated with cognitive control allocation and depressive vulnerability, including positive and negative affect, rumination, sleep quality, motivation, and lack of interest. Remitted MDD (rMDD) and ND individuals participated in three studies with daily (5 to 10) ESM measurements over a period of two weeks to four months. ESM compliance (calculated as the mean response rate and variability (SD) in response rate), inhibitory control (assessed with the Sustained Attention to Response Task), and factors related to depressive relapse vulnerability (positive and negative affect, rumination, sleep quality, motivation, and lack of interest) were assessed. Kendall’s correlations and Linear Mixed Effect models examined the relationships between ESM compliance, inhibitory control, and depressive vulnerability factors. Linear mixed effect models showed no evidence for a relationship (∆AIC below -2) between lab-based cognitive control and compliance. However, correlational analyses showed a positive relationship between mean compliance and inhibitory control [τb = .32, p=0.002; BF10=23.1] and a negative relationship between compliance variability and inhibitory control [τb = -.28, p=0.005; BF10=8.7]. The strength of the correlation was comparable to negative affect, which was also found to relate to mean compliance [τb = -0.20; p below 0.001; BF10=2091.4] and compliance variability [τb = 0.20; p below 0.001; BF10=1896.3]. Changes in compliance over days did not differ between rMDD and ND individuals (∆AIC below -2). No significant associations between compliance and other vulnerability factors were observed (p below 0.05).These findings indicate mixed evidence for ESM compliance as a reflection of cognitive control, with correlations suggesting that cognitive control and negative affect are associated with compliance. No significant associations with other vulnerability factors were found. Future research could explore the utility of ESM compliance in assessing cognitive control and goal pursuit using an optimized design for that question.
AI for Scientists: Using Cognitive Task Analysis to Guide Scientific AI
Authors: Irons Jessica , Cooper Patrick , McGrath Melanie , Duenser Andreas
Published: October 2024

Advancements in artificial intelligence (AI) have the potential to fundamentally change how science is conducted. To ensure scientists can employ AI tools effectively, design should be grounded in a deep understanding of the work context. The current study proposes using a modified cognitive task analysis to map out scientific workflows and decision-making processes. Following this approach, we conducted interviews with scientists from two structural biology case studies, genome annotation and protein crystallisation. Analyses revealed the major challenges facing scientists and the strategies they employed to overcome them. We also identified key opportunities and implications for AI in workflows, capturing findings in a novel workflow diagram. Notable contextual differences emerged across the two case studies, highlighting the need for tailored AI solutions for different problems. Results highlight the utility of cognitive task analysis in understanding scientific workflows in their unique context, paving the way for strategic implementation of AI in science.
Competitor or complement? Swiss Training Firms’ Perspective on General Education
Authors: Wilson Anna , Bajka Scherwin M.
Published: October 2024

In knowledge economies, technological advancements have brought about new occupational skill demands. In accommodating these needs, many economies have expanded general education at the cost of vocational education and technical training (VET). This trend also permeates coordination-based economies, wherein firms provide the technical aspect of training (dual VET). Despite rapidly changing skill demands, the well-established collective action among training firms has remained intact. Yet, firms may change their perception of the importance of VET compared to general education, as it reshuffles their dependency on dual VET. In this paper, we explore how the expansion of general education tracks at the upper secondary level, along with firms’ academic requirements and use for higher educated workers, influence firms’ perception of general education at the upper secondary education level as being a competitor to initial dual VET programs. This perception is important as it may affect firms’ motivation to continue providing training and their broader adaptation to institutional change. Combining novel survey data with federal educational statistics, we show that a firm’s regional exposure to general education expansion at the upper secondary level has no significant effect on firms’ view of general education as a competitor. However, firms’ academic requirements and their need and use also for higher (general) educated workers better explain the outcome.
The PET@home Toolkit: A Process Evaluation Study
Authors: Reniers Peter , Hediger Karin , Declercq Ine J.N. , Enders-Slegers Marie-Jose , Gerritsen Debby , Leontjevas Ruslan
Published: October 2024

The Dutch PET@home Toolkit was developed to mitigate challenges and foster conversations andplanning concerning pets in long-term care at home. This process evaluation study aimed to evaluate the practical application of the toolkit on four topics: 1) satisfaction; 2) relevance; 3) feasibility; and 4) integration of the PET@home Toolkit materials in home care. Outcomes may be used to improve the toolkit materials to better align with the long-term care at home setting. Accounting for data saturation, professional caregivers (N=6), clients (N=2), and family caregivers (N=2) who used toolkit materials participated in semi-structured interviews. Interviews were analysed by two researchers in ATLAS.ti using an inductive-iterative approach. The researchers reached consensus on themes and clustering within interview topics. This led to the identification of the following topics and (themes): satisfaction (general impression, suggestions for improvement), relevance (awareness, planning, pet-related aspects in practice, impact on healthcare quality), feasibility (healthcare practice, competence, quantity), and implementation (digitalisation, task owner, piloting, timing). Several improvements were made to toolkit materials, such as providing clearer instructions for clientsin the information booklet. Participants acknowledged the toolkit could lead to better planning whilemitigating potential challenges concerning pets which may lead to longer-lasting relationships between clients and their pets
Delivering participatory food systems research in our own communities: reflections about co-production by community food researchers and community partners
Authors: Gardiner Hannah , Roughton Maria , Howard Lisa , Hunt Louise , Nisa Unis , Pettinger Clare
Published: October 2024

This article offers insights into delivering community-engaged research (co-production), from the perspectives of engaged citizens and community partners. It adds to scholarship addressing epistemic justice issues that the experiences of engaged citizens are rarely explored.The engaged citizens are community collaborators in FoodSEqual (a UKRI funded project aiming to co-produce solutions to food system inequality in four UK locations). During FoodSEqual’s delivery, it became clear contextual factors and practical delivery varied. To support shared learning, an in-person reflective session was held using the ‘open space method’ (Involve, n.d) (participants: Community Food Researchers (CFRs) (n=14), community coordinators (n=6)). Four key themes were defined during the session. A content analysis of observational notes was undertaken by a PhD Student (HG) and CFR (MR). Resulting outputs were checked with most of the original participants.Four areas identified as instrumental to successful community co-production were: 1. Engagement and building trust; 2. Co-designing practical research activities; 3. Balancing structure and flexibility; 4. Community engagement outside activities. Implications for practice include mitigating tensions between different ways of working, the need for better understanding and acknowledgement of community roles, and proposals for how the engagement model itself can contribute to food system transformation.
Women in International Negotiations: Evidence from the Council of the European Union
Authors: Huikuri Tuuli-Anna , Hunter Tom McCrae
Published: October 2024

What is the impact of increasing women’s participation in international negotiations? Although a growing international relations scholarship is examining the role of women leaders on interstate conflict and crisis bargaining, we know less about the wider dynamics of women getting a seat in the rooms where the terms of international cooperation are negotiated. Long-standing assumptions hold that women are more peaceful and cooperative than men. However, it has also been suggested that women who have made it to the relevant top offices are likely unrepresentative, and have to adjust their behavior to meet expectations. Leveraging novel data on the gender of speakers in over 3,500 negotiation statements at the Council of the EU in 2011-2016, we investigate whether women employ systematically different negotiation rhetoric than men. Building on existing work on international relations, psychology, and business studies, we investigate empirically the individual-level sources of negotiation strategies, as well as their likely impact on international cooperation.
Bridging the Mental Health Care Gap for International Students via Digital Interventions
Authors: Xie Qiang , Zhu Yiqin , Lin Tao , Yin Zizhuo , Goldberg Simon
Published: October 2024

Objectives: Mental health issues among international students are concerning. However, international students tend to underutilize and benefit less from traditional mental health services compared to their domestic counterparts. The current paper proposes digital mental health interventions (DMHIs) as a promising approach to bridge mental health inequities faced by international students. Methods: We explore the definition, types, and efficacy of DMHIs. We outline the unique promise of these interventions in reducing barriers to health service access encountered by international students. To illustrate these points, we discuss example studies of DMHIs for international students. Results: Recent studies have supported the potential benefits of DMHIs for improving international students’ psychological distress, well-being, and help-seeking outcomes. However, many scientific questions remain unsolved. Discussion: To optimize the potential of these interventions for international students, researchers should conduct well-powered randomized controlled trials, examine correlates of intervention use, design single-session interventions, co-develop interventions with the international student community, integrate interventions within the larger system, incorporate ecological momentary assessment and digital phenotyping, and leverage immersive and interactive digital technology.
Explaining Away the Illusion of Consensus
Authors: Connor Desai Saoirse , Lee Jaimie , Hayes Brett
Published: October 2024

Consensus among sources often signals a claim’s trustworthiness. However, when all sources simply echo information from a single origin, an “illusion of consensus” can arise, leading individuals to feel equally convinced by a dependent consensus (a single, repeatedly cited source) as by an independent consensus (corroborated information from multiple sources), unless their independence is made clear. This effect may occur because repetition can be perceived as a cue for credibility; thus, undermining source credibility might prompt individuals to discount a dependent consensus. We conducted three experiments to test whether whether explaining that source repetition resulted from biases in source selection can enable people to discount a dependent consensus. Participants engaged in a political polling task to assess confidence in claims supported by an independent consensus (news outlets citing different polling companies), a dependent consensus without explanation (news outlets citing the same polling company), or a dependent consensus accompanied by explanations that either boosted or undermined source credibility. While an independent consensus was more persuasive than dependent consensus, explanations alone did not affect claim confidence (Experiments 1-2a, 2b). In Experiment 3, when participants generated their own explanations for why source repetition might undermine reliability, confidence in claims supported by a dependent consensus was reduced. These findings suggest that social inference processes contribute to the illusion of consensus, with implications for interventions designed to mitigate the impact of misleading claims repeated in media.
Essential Workers and Wage Inequality: Wage Differentials before and during the Covid-19 Pandemic, 2006 to 2022
Authors: Janietz Christoph
Published: October 2024

In 2020, several governments declared specific occupations as essential for maintaining the functioning of society in response to the Covid-19 pandemic. A current question in the public debate on fair pay is whether essential workers are sufficiently remunerated. Using data from the Netherlands, I analyze the wages of essential workers relative to other workers before and during the Covid-19 pandemic. Wage decompositions indicate that, between 2006 and 2019, essential workers earned less compared to other workers within higher-paid strata, while they earned more within lower-paid strata of the occupational structure in the Netherlands. These wage differentials are shaped by sex composition and sectoral employment. In addition, I employ a difference-in-differences design based on quarterly data between 2017 and 2022 to assess whether the onset of the Covid-19 pandemic reduced an existing average wage gap in response to an increasing public appreciation of essential work. Results indicate that the collective experience of the Covid-19 pandemic has not benefited essential workers in the short-term.
“Crikey! Let’s keep it cozy like a joey in a pouch– not too hot or cold!” Can humour or compassion encourage sustainable heater use at hotels?
Authors: Greene Danyelle , Zinn Anna Kristina , Chen Qingqing , Serati Reza , Portmann Marius , Dolnicar Sara
Published: October 2024

In the hotel industry, the management of room temperatures plays a crucial role in both environmental impact and energy costs. Small changes, such as reducing heating by 1°C, can save around 6% on electricity. Despite the significant impact, there is a notable scarcity of interventions aimed at promoting sustainable air conditioner use among guests. Most pro-environmental behaviour-change interventions in tourism focus on environmental messaging and negative appeals, with mixed effectiveness. Positive emotions like amusement (humour) and self-transcendent emotions (compassion) have been largely overlooked but have shown potential in other research contexts. The current series of studies assesses the comparative effectiveness of messages designed to trigger humour, compassion, and environmental beliefs on sustainable air conditioner use. In Study 1, we develop and evaluate four alternative messages for each theoretical construct. We use the most effective message for each construct (e.g., the most amusing humour message) in Studies 2 and 3. Study 2 serves as a manipulation check to ensure the messages effectively triggered the intended theoretical constructs. It also assesses behavioural intentions and emotional reactions. Study 3 tests the impact of the interventions on real behaviour in a quasi-experimental field study. Study 2 shows that each message effectively strengthens its respective theoretical construct (e.g., the environmental message strengthened environmental beliefs). The field study demonstrates that all three messages, along with a basic behaviour instruction message, increase sustainable air conditioner use. The humour message had an advantage over the others, being positively perceived by participants and not causing negative reactions. Therefore, framing sustainable air conditioner use instructions humorously appears to be a promising strategy in the hotel context. While our humour message is tailored to the Australian winter context, future research should explore the applicability of humour-based interventions in diverse cultural and climate settings to enhance sustainable air conditioner practices globally.
PENERAPAN 4C SKILLS DALAM PEMBELAJARAN ABAD 21 DI SEKOLAH DASAR
Authors: Realitawati Realitawati , Ikrom Fadhli Dzil , Herawan Endang , Kadarsah Deni
Published: October 2024

Elementary schools play an important role in developing students' understanding and skills. Therefore, the transformation of elementary schools is very important to produce a critical, creative and innovative generation capable of facing the challenges of the 21st century. The purpose of this research is to determine the application of 4C skills (Critical Thinking Skills, Creativity and Innovation Skills, Communication Skills, Collaboration Skills) in teachers' teaching in 21st century learning at SD Negeri Serang 20. The research method uses qualitative methods by conducting structured interviews. The target respondents were all 10 teachers of SD Negeri Serang 20. The results of the research show that the respondents have integrated 4C skills into the curriculum and daily learning activities.
PENGARUH PENGGUNAAN MEDIA AJAR BERBASIS TEKNOLOGI ANIMAKER PADA MATA PELAJARAN IPAS TERHADAP MINAT BELAJAR PADA SISWA SEKOLAH DASAR
Authors: Erisnaentin Meilinda , Abdullah Kusmajid
Published: October 2024

: The effect of using technology-based learning media on science subjects. So you can see how strong the influence of technology-based learning media is on increasing students' interest in learning in the learning process. The aim of this research is to determine the effect of using Animaker technology-based teaching media on class 4 students' interest in learning. This type of research uses a quantitative approach with experimental research methods. The method used to find the effect of treatment on the thing being researched. Therefore, in this experimental method there will be special treatment to determine whether or not there is an influence in the research. The method used by researchers is Quasi Experimental design. hypothesis testing, the results of the independent t test show that there are significant differences between the two groups. Levene's Test shows that the variance of the two groups is considered the same (Sig. 0.804). The t-test results show a t-statistic value of 5.298 with 54 degrees of freedom and a significance value of 0.000. The mean difference between the experimental and control groups was 8.964 with a 95% confidence interval ranging from 5.572 to 12.356. These results indicate that the use of Animaker teaching media significantly increases students' interest in learning compared to conventional learning methods. It is concluded that there is a significant influence from the use of Animaker technology-based teaching media on students' interest in learning in science and science subjects in class 4 at SDN Grogol Utara 09. Analysis statistics show that there is a significant difference in the post-test results between the experimental group using Animaker and the control group using conventional methods. With the experimental group's average post-test results being slightly higher, this difference is statistically large enough to be declared a significant difference.
METODOLOGIAS ATIVAS EM AULAS DE BIOLOGIA NO ENSINO MÉDIO
Authors: CARLOS DA SILVA LUIZ , FEITOZA DA SILVA FRANCIENE
Published: October 2024

A educação vem passando por mudanças, saindo da visão tradicional que o professor é a figura central e os estudantes apenas os receptores de conteúdos de forma mecânica. Assim, é necessária cada vez mais a busca por novos métodos de ensino que possibilitem uma aula mais diversificada. As metodologias ativas no ensino de biologia é muito importante, pois permitem que os estudantes se tornem mais participativos e protagonistas, aprendendo assim de forma significativa. No entanto, o objetivo desse trabalho de revisão bibliográfica constitui em analisar as contribuições das metodologias ativas utilizadas em aulas de biologia no ensino médio. Com isto, foram selecionadas pesquisas bibliográficas em trabalhos científicos no Google Acadêmico publicadas no período de 2018 a 2022, visando referências que abordassem informações sobre as metodologias ativas e ensino de biologia no ensino médio com os descritores: Biologia, Metodologias Ativas e Estratégias de Ensino. Na fundamentação teórica apresentamos três categorias: Contexto Histórico, Ensino de Biologia, Metodologias Ativas. A seleção foi feita mediante o titulo a leitura dos resumos aqueles que mais se aproximassem do assunto foram coletados para estudo, os que não tratavam das metodologias ativas foram excluídos. Nos resultados apresentamos que as metodologias ativas vêm sendo cada vez mais difundidas no ensino de biologia. Porém, ainda são encontrados poucos trabalhos sobre essa supracitada temática. As conclusões demonstram que através dos trabalhos analisados que a uma grande necessidade de adotar metodologias ativas no ensino de biologia. Elas são fundamentais para que os objetivos do ensino sejam alcançados, como também constituem maneiras de alteração do ensino tradicional, pois trazem uma maior autonomia do aluno.
Strategia prezydenta Litwy wobec Ukrainy w latach 2022–2024
Authors: Malużinas Martinas
Published: October 2024

Celem artykułu jest analiza i ocena retoryki oraz strategii podjętej przez prezydenta Litwy wobec Ukrainy w latach 2022–2024 po rosyjskiej inwazji na Ukrainę. Według postawionej hipotezy zagrożenie rosyjskie prowadzi do intensyfikacji współpracy Litwy na arenie międzynarodowej oraz zmiany priorytetów strategicznych, zwłaszcza w kontekście Ukrainy. Przyjęta metodologia bazuje na studium przypadku i teorii adaptacyjnej, co pozwala dokonać szczegółowej analizy polityki zagranicznej państwa litewskiego. Wyniki badań pokazują, iż aktywna polityka prezydenta Litwy na rzecz Ukrainy postrzegana jest jako element zwiększenia litewskiego bezpieczeństwa oraz umocnienia międzynarodowej roli tego państwa.
Analisis Generator Sinkron Unit 2 Akibat Overheating Di Pembangkit Listrik Tenaga Gas MPP Balai Pungut
Authors: Abrar Tanjung  , Zafid Maulana  , Hazra Yuvendius
Published: October 2024

Generator sinkron adalahh mesin sinkron pengubah energi mekanik menjadi energi listrik yang memiliki frekuensi putar rotor sama dengan frekuensi tegangan yang dibangkitkan. Generator sinkron yang ditinjau adalah generator sinkron pada PLTG MPP Balai Pungut. Tujuan penelitian ini adalah menganalisis kenaikan temperatur akibat perubahan generator sinkron serta menganalisis efisiensi generator sinkron terhadap rugi-rugi daya akibat overheating. Kenaikan temperatur disebabkan oleh pengaruh beban, arus jangkar, rugi-rugi total yang bervariasi. Dari hasil analisa dan perhitungan yang dirata-ratakan pada bulan April, Mei, Juni 2021 dapat dilihat bahwa, kenaikan temperatur disebabkan oleh pengaruh beban yang bervariasi. Temperatur tertinggi terjadi pada bulan April dengan temperatur 85,43°C pada beban 23,05 MW dan arus jangkar 1160,146 A, serta temperatur terendah terjadi pada bulan Mei dengan temperatur 52,47°C pada beban 12,60 MW dan arus jangkar 641,915 A. Efisiensi generator sinkron unit 2 PLTG MPP Balai Pungut dipengaruhi oleh rugi-rugi total generator yang menyebabkan terjadinya overheating. Semakin meningkat efisiensi nya maka rugi-rugi total nya juga meningkat, efisiensi terendah yang terjadi pada bulan April, Mei, Juni 2021 terdapat pada bulan Mei dengan efisiensi 93,03% dan rugi-rugi total nya 0,930 kW, serta efisiensi tertinggi terdapat pada bulan April dengan efisiensi 95,05% dan rugi-rugi total nya 1,190 kW.
Studi Karakteristik Generator Sinkron Terhadap Perubahan Beban di PT. PLTG Mobile Power Plant Balai Pungut
Authors: Tara Sukmana Iqbal , Arlenny Arlenny , Zondra Elvira , Monice Monice
Published: October 2024

Generator sinkron adalah mesin sinkron pengubah energi mekanik menjadi energi listrik yang memiliki frekuensi putar rotor sama dengan frekuensi tegangan yang dibangkitkan. Pada generator, energi mekanik didapat dari penggerak mula yang bisa berupa mesin diesel, turbin, baling-baling dan lain-lain.Pada pembangkit-pembangkit besar, salah satu alat konversi yang sering digunakan yaitu generator sinkron 3 phasa. Generator sinkron yang ditinjau adalah generator sinkron pada PLTG Balai Pungut. Tujuan penelitian ini adalah untuk menganalisa generator sinkron tiga fasa terhadap perubahan beban. Dari hasil analisa data bulan Februari dan Maret dirata ratakan menjadi 7 hari dan 7 tabel, isi tabel berdasarkan logsheet yaitu Beban, Arus Eksitasi, Tegangan Output. Beban generaotr yang bersifat fluaktif atau berubah ubah tiap jam nya. Beban terendah di hari senin yaitu 11 MW dan yang tertinggi 24,7 MW, Beban terendah di hari Selasa 15 MW dan yang tertinggi 26,64 MW, Beban terendah di hari Rabu 10,64 MW dan yang tertinggi 24,14 MW, Beban di hari Kamis adalah 14,25 MW hingga yang tertinggi 26,92 MW, Beban hari Jumat 13,02 MW dan 24,02 MW,  Beban tertinggi dihari sabtu yaitu 26,82 MW, Beban hari minggu adalah 11,25 MW untuk yang terendah dan 24,82 MW saat beban tertinggi. Efisiensi generator berubah ubah berkisar 75% hingga 86%.
Reconstruction of a matrix of genotypic correlations between variants within a gene for joint analysis of imputed and sequenced data
Authors: Svishcheva G. R. , Kirichenko A. V. , Belonogova N. M. , Elgaeva E. E. , Tsepilov A. Ya. , Zorkoltseva I. V. , Axenovich T. I.
Published: October 2024

When combining imputed and sequenced data in a single gene-based association analysis, the problem of reconstructing genetic correlation matrices arises. It is related to the fact that for a gene, we know the correlations between genotypes of all imputed variants and the correlations between genotypes of all sequenced variants, but we do not know the correlations between genotypes of variants, one of which is imputed and the other is sequenced. To recover these correlations, we propose an efficient method based on maximising the determinant of the matrix. This method has a number of useful properties and has an analytical solution for our task. Approbation of the proposed method was performed by comparing reconstructed and real correlation matrices constructed on individual genotypes from the UK biobank. Comparison of the results of gene-based association analysis performed by the SKAT, BT and PCA methods on reconstructed and real matrices, using modelled summary statistics and calculated summary statistics on real phenotypes, showed high quality of reconstruction and robustness of the method to different gene structures.
Expression profiles of genes involved in lignan synthesis in developing flax seeds
Authors: Pushkova Е. N. , Dvorianinova E. М. , Povkhova L. P. , Rozhmina T. А. , Novakovskiy R. O. , Sigova Е. A. , Dmitriev А. А. , Melnikova N. V.
Published: October 2024

Flax seeds are the richest plant source of lignans, which prevent the development of many diseases. Secoisolariciresinol diglucoside (SDG) is the predominant lignan in seeds of the cultivated species Linum usitatissimum. We sequenced transcriptomes of flax seeds at five developmental stages for 8 varieties differing in lignan content grown under three different conditions and evaluated the expression of PLR1 and UGT74S1 genes, which play a key role in SDG synthesis. The co-expression of PLR1 and UGT74S1 genes was detected, and the expression level of these genes was observed to change tens and hundreds of times during seed development, confirming their role in SDG synthesis in flax seeds. Low temperature (16 °С) and abundant watering resulted in a shift of the maximum expression level of both genes to later dates (14th day after flowering) compared to poor watering and high temperature (24 °С) and optimal conditions (20 °С) (7th day after flowering). Meanwhile, the expression level of PLR1 and UGT74S1 genes was lower under high temperature and poor watering than under optimal conditions. No association was found between lignan content in seeds of the studied flax varieties and the expression level of PLR1 and UGT74S1 genes. Our results provide important information on the contribution of genotype and environment to the expression of key genes of SDG synthesis, which is also necessary for the development of optimal approaches to obtain lignan-rich flax seeds.
The epistemological turn and the episteme of the social in the intellectual discourse of the sixteenth and seventeenth centuries
Authors: Fyodorov Sergey E.
Published: October 2024

The article presents a synthesis of the author’s findings on the antiquarian and erudite texts from England, France, and Germany that were produced during the sixteenth and seventeenth centuries. It is demonstrated, for the first time, that European intellectuals’ sustained interest in the construction of individual “fragments” of social reality predetermined the consistent development of certain descriptive schemes for the realisation of this project, initially focusing on the example of various categories of nobility, and subsequently on other social groups. The author places particular emphasis on the accessibility of comprehensive techniques in conjunction with narrative schemes, which are employed in the portrayal and classification of the nobility. Indeed, the author’s argument hinges on the assertion that such techniques facilitated this so-called antiquarian/erudite episteme, which in turn permitted the evaluation of perspectives for the construction and depiction of the “social” during this period. Whereas a new episteme completely transfigured all foregoing workings in understanding of intra- and extra-group communications, what is meant here is an epistemological turn occurred in the Early Modern intellectual discourse. Using various tools of discourse analysis, the author demonstrate, for the first time, that the kernel of the epistemological turn lies in a reinterpreting of a descriptive efficacy of the medieval corporate theory, which viewed all individual and collective agencies as collective or fictitious bodies devoid of personal identity. The new narrative scheme introduced in antiquarian and erudite texts diversified the functional model of social relations relevant to medieval epistemology.
“Social” terminology in sir John Skene’s lexicography “De verborum significatione”
Authors: Palamarchuk Anastasia A.
Published: October 2024

The process of specification of the social and, in particular, the process of demarcation between the social and the legal spheres in Early Modern European intellectual discourse exhibited both general regularities and elements contingent on the regional specificity of intellectual traditions and institutional practices. In the article, the author examines the Scottish version of this process, with the lexicography of the Scottish civil lawyer Sir John Skene (1549–1617) “De Verborum Significatione” serving as a case in point. The analysis of the social concepts included in the lexicography demonstrates that the heterogeneity of the genesis of strata and groups within the Scottish nobility, as observed by contemporaries, precluded the establishment of a hierarchy of noble titles and dignities within the Scottish kingdom. Consequently, reflection on the nobility as a social phenomenon was also prevented. Conversely, the ascendancy of civil law, with its rigorously delineated subject matter and enduring lexical apparatus, fostered the elaboration of the legal domain. However, this process also impeded the differentiation between the legal and the social. The author demonstrates that numerous concepts that would subsequently be imbued with particular social connotations within the Scottish intellectual tradition during the seventeenth century were nevertheless still regarded as an intrinsic component of the legal framework within the community of the kingdom. When referenced in the Scottish laws and parliamentary acts examined by Skene, these concepts were closely associated with legal privileges, judicial procedure, or the distinctive characteristics of property relations.
Biotechnological Production of the Recombinant Two-Component Lantibiotic Lichenicidin in the Bacterial Expression System
Authors: Antoshina D. V. , Balandin S. V. , Tagaev A. A. , Potemkina A. A. , Ovchinnikova T. V.
Published: October 2024

Lantibiotics are a family of bacterial antimicrobial peptides synthesized by ribosomes that undergo post-translational modification to form lanthionine (Lan) and methyllanthionine (MeLan) residues. Lantibiotics are considered promising agents for combating antibiotic-resistant bacterial infections. This paper presents a biotechnological method for obtaining two components of the lantibiotic lichenicidin from Bacillus licheniformis B-511 – Lchα and Lchβ. A system has been developed that allows co-expression of the lchA1 or lchA2 genes, encoding the precursors of the α- or β-components, respectively, with the lchM1 or lchM2 genes of the modifying enzymes LchM1 and LchM2 in Escherichia coli cells. The developed system of heterologous expression and purification made it possible to obtain, with high yield, post-translationally modified recombinant Lchβ, completely identical to the natural peptide in structure and biological activity.
Impact of Effectors on the Catalytic Activity of Galactonolactone Oxidase from Trypanosoma cruzi
Authors: Chudin A. A. , Kudryashova E. V.
Published: October 2024

The influence of the structure of the effectors, 1,4-benzoquinone, coenzymes Q and their structural analogues, on the activity of galactonolactone oxidase from Trypanosoma cruzi (TcGAL) and the homologous enzyme L-galactono-1,4-lactone dehydrogenase from Arabidopsis thaliana (AtGALDH) was studied. Using two forms of AtGALDH, natural (dehydrogenase) and mutant (exhibiting oxidase activity), the role of 1,4-benzoquinone and its analogs as electron acceptors of AtGALDH and TcGAL was revealed. It has been established that compounds containing methoxy groups are more effective electron acceptors for TcGAL (coenzyme Q0, 2,6-dimethoxy-1,4-benzoquinone) compared to compounds without OCH3 groups (2,5-dihydroxy-1,4-benzoquinone). Using 2,6-dimethoxy-1,4-benzoquinone as an electron acceptor, an approach to the spectrophotometric measurement of TcGAL activity by changes in the absorption of the electron acceptor in the absence of additional components (a dye that becomes colorless when interacting with the reaction product, ascorbate) is proposed. The results obtained allow for a more targeted search for TcGAL inhibitors, which can be considered as the basis for the development of selective drugs against Chagas disease caused by T. cruzi.
Comparative Behavior Analysis of Cy5-Pyrimidine Nucleotides in the Rolling Circle Amplification
Authors: Lapa S. A. , Chirkova P. A. , Surzhikov S. A. , Kuznetsova V. E. , Shershov V. E. , Chudinov A. V.
Published: October 2024

Two pairs of Cy-5-labeled dU and dC triphosphates with similar electroneutral fluorophore structures differing in the length of the hydrocarbon linker between the fluorophore and the nitrogenous base were synthesized. A comparative analysis of their substrate behavior in the rolling circle amplification (RCA) using Bst 3.0 DNA polymerase was carried out. It was found that nucleotides with a long linker between the fluorophore and pyrimidine base are more efficiently incorporated into the growing DNA chain, while nucleotides with a short linker inhibit RCA less. In each of the dU and dC pairs with similar fluorophores and linkers, fluorescently labeled uridine derivatives demonstrated a high embedding density. It was found that with simultaneous incorporation of labeled dU and dC, the inhibitory effect does not summarise. This gives grounds for a more careful study of various Cy5-dC variants in order to increase a sensitivity of the analysis with simultaneous introduction of labeled dU and dC.
Physicochemical Features of Thrombin Binding to Platelet Membrane
Authors: Kerimov R. R. , Nechipurenko D. Yu. , Panteleev M. A.
Published: October 2024

Thrombin is a key enzyme of the blood coagulation system, which has been actively studied since the beginning of the last century. The formation of thrombin from prothrombin in the area of vessel injury leads not only to the formation of fibrin – an important structural component of the hemostatic clot – but also to the activation of platelets, endothelium and immune system cells. The binding of thrombin to the platelet surface is thought to play a critical role in the process of platelet activation and may also ensure the maintenance of a high concentration of thrombin within the thrombus due to the concentration of protease on the platelet surface. To date, all major thrombin receptors on platelets have been thoroughly characterized: through various experimental methods, the physicochemical parameters of the corresponding intermolecular interactions have been established. Since the interaction of thrombin with platelets leads to their activation, which includes changes in the number of receptors as a result of granule secretion, the interpretation of the observed kinetic binding curves faces a number of difficulties. It is known that some receptors as a result of platelet activation are able to redistribute on the membrane and form dimers and clusters, which makes the kinetics of thrombin binding to platelets an extremely complex process depending on many factors, such as activator concentrations, platelet state, and other local parameters of the system. This review aims to describe the current understanding of the interaction of thrombin with the platelet membrane and to outline important unresolved issues in this area of research. The survey provides not only information on structural and kinetic features of thrombin binding to individual platelet membrane proteins, but also analyzes the relationship between the relevant interaction parameters and previously obtained data on the integral kinetics of protease binding to the platelet surface.
Chess and explainable AI
Authors: Björnsson Yngvi
Published: October 2024

Chess, once famously referred to as the drosophila of artificial intelligence (AI) research, has been a significant domain for developing intelligent AI agents capable of achieving super-human performance in domains previously dominated by humans. However, the emphasis on unceasingly improved playing strength has come at the cost of neglecting other fundamental aspects of intelligent agents, such as being capable of explaining the rationality behind their decisions in human-understandable terms. The need for such capabilities may be even more profound now than before, partly because such agents may be capable of learning novel concepts of interest to us humans, for example, as recently demonstrated in the game of chess. In this paper, we survey the state of explainable AI in chess-playing agents, arguing that chess may indeed hold a promise as an admissible domain for explainable AI.
Effect of chest expansion resistance exercise and respiratory muscle stretching on respiratory function and gait endurance in patients with stroke
Authors: Lee Jiyeon , Kim Jinseop
Published: October 2024

Background

Limited chest expansion and asymmetry in the respiratory muscles after a stroke lead to poor ventilation and reduced physical performance.

Objectives

To determine the effect of chest expansion resistance exercise and respiratory muscle stretching on respiratory function and gait endurance in patients with stroke.

Methods

Thirty stroke patients were randomly assigned to a chest expansion resistance group (CERG), a respiratory muscle stretching group (RMSG), and a control group (CG). CERG and RMSG received chest expansion resistance and respiratory muscle stretching, respectively, 3 times a week for 8 weeks. Respiratory function, respiratory muscle strength, and gait endurance were measured before and after the intervention period.

Results

The experimental groups, CERG and RMSG, showed significant improvements in respiratory function variables ( p < .05). For respiratory muscle strength variables, maximal inspiratory pressure (MIP) in the CERG and maximal expiratory pressure (MEP) in the RMSG showed significant changes compared to the CG ( p < .05). Both CERG and RMSG also showed significant improvements in the 6MWT compared to the CG ( p < .05).

Conclusion

Chest expansion resistance exercise would be a more effective method, while both chest expansion resistance exercise and respiratory muscle stretching are helpful in improving respiratory function and gait endurance.