bluuebunny/crossref_metadata_2025 huggingface dataset:
Morphological and molecular identification of new records and new host plants of powdery mildews (Erysiphaceae) from Mexico
Authors: Gregorio-Cipriano Rosario , González Dolores , Félix-Gastelum Ruben , Chacón Santiago
Published: January 2022

Powdery mildew is one of the most severe diseases affecting Cucurbitaceae. We identify the members of Erysiphaceae infecting cucurbits in three producing regions in Mexico. We determined that Golovinomyces ambrosiae (Schwein.) U. Braun & R.T.A. Cook, Neoerysiphe sechii R. Gregorio-Cipriano & D. González, and Podosphaera xanthii (Castagne) U. Braun & Shishkoff infected cultivated and wild cucurbits species or subspecies. Leaf samples showing symptoms and signs of powdery mildew were collected from the northwestern, central western, and eastern regions of Mexico between 2017 and 2020. Species associated with the disease were identified based on morphology and internal transcribed spacer rDNA sequences. All powdery mildew specimens presented only the anamorph. Podosphaera xanthii was the predominant species; it was found in 84.76% of the samples and in 13 out of 14 species or subspecies of cucurbits. Neoerysiphe sechii was found in 15.24% of the samples and in only four cucurbit species from the central western and eastern regions of Mexico. Golovinomyces ambrosiae was documented for the first time in a Cucurbitaceae species (Sicyos deppei G.Don) from central west Mexico. Three new hosts were registered for N. sechii (Cucurbita ficifolia Bouché, Echinopepon milleflorus Naudin, and Sicyos laciniatus L.) and eight for P. xanthii (Cucurbita argyrosperma C.Huber, Cucurbita argyrosperma subsp. sororia (L.H.Bailey) Merrick & D.M.Bates, C. ficifolia, Cucurbita okeechobeensis subsp. martinezii (L.H.Bailey) T.C.Andres & G.P.Nabhan ex T.W.Walte, Cucurbita radicans Naudin, Sechium edule (Jacq.) Sw., S. laciniatus, and S. deppei).
Assessing the quality of a network of vector-field sensors
Authors: Smiga Joseph A.
Published: January 2022

An experiment consisting of a network of sensors can endow several advantages over an experiment with a single sensor: improved sensitivity, error corrections, spatial resolution, etc. However, there is often a question of how to optimally set up the network to yield the best results. Here, we consider a network of devices that measure a vector field along a given axis; namely for magnetometers in the Global Network of Optical Magnetometers for Exotic physics searches (GNOME). We quantify how well the network is arranged, explore characteristics and examples of ideal networks, and characterize the optimal configuration for GNOME. We find that by re-orienting the sensitive axes of existing magnetometers, the sensitivity of the network can be improved relative to the past science runs.
A representação de outsiders em Estranhos no Paraíso
Authors: Pacheco Helena Lukianski , Silva Melina Aparecida dos Santos
Published: January 2022

O objetivo deste artigo é analisar o filme Estranhos no Paraíso (Stranger than Paradise, 1984), do cineasta estadunidense Jim Jarmusch. Propomos uma reflexão sobre o fato de que, ao longo do século XX, “imagens modelares” do American way of life constituíram uma das várias configurações estadunidenses das relações estabelecidos-outsiders, com o apoio da mídia e da indústria cultural. Desta forma, a análise fílmica de Estranhos no Paraíso terá como um dos principais aportes teóricos a concepção de outsiders. Partiremos da questão: como o filme Estranhos no Paraíso mostra uma representação crítica das relações estabelecidos-outsiders instauradas pelo american way of life?
Em Quarentena – um podcast da Agência Mural de Jornalismo das Periferias
Authors: Rovida Mara
Published: January 2022

O isolamento social, demandado a partir de 2020 por conta da pandemia, interferiu no fazer jornalístico, da apuração à narrativa. Este artigo apresenta uma pesquisa exploratória estruturada em abordagem de análise de conteúdo, cujo objetivo é compreender algumas das estratégias narrativas do jornalismo das periferias, no contexto de 2020. Para tanto, realizou-se uma análise dos 40 primeiros episódios do podcast Em Quarentena, produzido por um coletivo de jornalistas que atua na Região Metropolitana de São Paulo (RMSP), maior macrometrópole brasileira. Este trabalho está inserido num universo reflexivo mais amplo, elaborado a partir de um estudo sobre a produção jornalística nas periferias da RMSP que vem sendo desenvolvido desde 2018 e que, portanto, serve de base para a presente discussão.
Contra estigmas e generalizações: o direito à voz e as estratégias de apagamento e invisibilidade do sujeito no texto jornalístico
Authors: Moreira Fernando de Freitas
Published: January 2022

Neste artigo, desenvolvemos uma observação crítica sobre a representatividade identitária da alteridade na mídia a partir de uma abordagem transdisciplinar. Partindo de uma análise sociológica e cultural do sistema de produção de consensos em que se insere o fazer jornalístico, buscamos identificar estruturas subjacentes a ele. Metodologicamente, portanto, optamos pelo paradigma do estruturalismo. Em seguida, comparamos o tratamento e a construção do éthos do sujeito do enunciado em duas reportagens: a primeira, um desdobramento do rompimento da barragem da Vale, em Brumadinho, mostrando como as vítimas da mineradora foram retratadas na narrativa; a segunda, um perfil de Ricardo Corrêa da Silva, pejorativamente chamado de Fofão da Augusta, por suas características físicas e pelo hábito de frequentar a famosa rua paulistana. Por fim, propomos uma discussão sobre as possibilidades de inclusão do sujeito que estava à margem, o outro, mostrando que sua individualização é possível e evita estereotipagens preconceituosas.
Experimentações narrativas em Twin Peaks: The Return: narração paramétrica na ficção televisiva contemporânea
Authors: Quaioti Henrique Bolzan , Ferraraz Rogério
Published: January 2022

O objetivo deste artigo é identificar a existência de narração paramétrica (conceito originalmente aplicado por David Bordwell a certas obras fílmicas) na ficção televisiva contemporânea, bem como apontar uma hipótese sobre o propósito do uso desse modo narrativo. Para tanto, elegemos como corpus a série "Twin Peaks: the return" (2017), dirigida por David Lynch e escrita por ele e por Mark Frost. Acreditamos ser possível identificar que existe pelo menos um evento narrativo na série que pode ser considerado paramétrico, que denominamos “Dale Cooper letárgico”. Através da análise desse evento narrativo, pretendemos demonstrar, que, usando uma narrativa paramétrica, Lynch e Frost subvertem grande parte das convenções que a própria série original engendrou em 1990, trazendo, assim, novas experimentações à ficção televisiva.
Das ruas ao tapete vermelho: o pañuelazo de Que sea ley como apropriação do espaço estésico
Authors: Vaz Aline
Published: January 2022

O objetivo desta pesquisa é analisar o pañuelazo verde, marcha pela descriminalização do aborto realizada no tapete vermelho no Festival de Cannes de 2019, como uma forma de vida que se constitui na apropriação do espaço estésico. Neste contexto, a partir do “agir com”, potencializa-se o “agir contra”, uma maré verde (progressista) que se manifesta em resposta a uma maré azul (conservadora). Logo, verificando matérias jornalísticas online de distintos países, concluímos que a manifestação de artistas e ativistas é capturada e midiatizada, tornando-se uma experiência estética e comunicacional que transborda o lançamento do filme Que sea ley no Festival de Cannes, como um vetor de experiência estésica que se organiza em torno de movimentos sociais e produtos mediatizados.
A linguagem cinematográfica como linguagem cotidiana
Authors: Odin Roger , Sousa Eduardo Paschoal de
Published: January 2022

Este artigo mostra como o celular ou, mais precisamente, o smartphone, permitiu, pela primeira vez na história do cinema, a instauração da linguagem cinematográfica como linguagem cotidiana, ou seja, como operador no espaço da comunicação cotidiana. Para isso, colocamos em evidência as principais funções dessa linguagem nesse espaço, analisamos sua forma e nos interrogamos sobre as consequências dessa mudança de status.
Criando pontes entre identidade, cultura e nação: o uso de Freire no intercâmbio estudantil em Gana
Authors: Steeves H. Leslie
Published: January 2022

Este ensaio mostra como a pedagogia de Paulo Freire tem informado um intercâmbio anual imersivo e de longa duração de estudantes de jornalismo e comunicação da Universidade de Oregon, EUA, em Gana, África Ocidental. Os alunos são diversos por classe econômica, identidade racial e étnica, gênero, sexualidade, deficiência e formação cultural. Eles são duplamente desafiados a viver juntos e a trabalhar em diferentes estágios em um ambiente cultural desconhecido, ao lado de ganeses, enquanto completam tarefas e atingem resultados de aprendizagem do programa. Os conceitos e métodos de Freire buscam quebrar barreiras entre professores e alunos e capacitar todos os participantes ao mesmo tempo em que os engajam na formação educativa.
Consciência crítica e emancipação cultural em legados (Sul) africanos da comunicação para a mudança social
Authors: Chasi Colin , Rodney-Gumede Ylva
Published: January 2022

Neste artigo, reconhecemos o pensamento freiriano como fundamental para a articulação de um dos quatro principais fluxos de influência às abordagens sul-africanas de comunicação e mudança social. Sabelo Ndlovu-Gatsheni (2017) afirmou que os estudos universitários na África têm três influências civilizacionais: “As próprias ricas culturas/ tradições da África, as culturas/tradições islâmicas e as culturas/tradições ocidentais” (p. 54). Este relato da influência da conscientização freiriana sobre a filosofia e as práticas do movimento Consciência Negra, originário da África do Sul na década de 1960, chama a atenção para o pensamento do Consciência Negra, considerado um marco fundamental nos estudos de comunicação e mudança social.
A visão de desenvolvimento e mudança social de Freire: experiências do passado, desafios do presente e perspectivas para o futuro
Authors: Suzina Ana Cristina , Tufte Thomas
Published: January 2022

Este artigo propõe tomar o pensamento de Freire como um modelo ou mesmo paradigma de comunicação, desenvolvimento e mudança social. Para tanto, primeiro delineamos a dimensão ontológica de Freire, apresentando e discutindo seus cinco princípios subjacentes. Em seguida, percorremos seu legado, apresentando e discutindo como ele inspirou três importantes pensadores ibero-americanos, Augusto Boal, Juan Díaz Bordenave e Boaventura de Sousa Santos. Finalmente, aprofundamos nossa análise da visão de Freire sobre desenvolvimento e mudança social, destacando como ele navega entre uma visão normativa fundamentada em uma aspiração utópica de mudança e uma metodologia muito sistemática e rigorosa, sua pedagogia libertadora.
Teses e dissertações de 1º de julho de 2020 a 30 de junho de 2021
Authors: MATRIZes Editores
Published: January 2022

Dados das teses e dissertações defendidas no PPGCOM/USP de 1º de julho de 2020 a 30 de junho de 2021.
Revendo Paulo Freire: uma introdução
Authors: Citelli Adilson , Suzina Ana Cristina , Tufte Thomas
Published: January 2022

A revista Matrizes lança este número especial dedicado ao centenário do nascimento de Paulo Freire (1921-1997). Os textos a serem lidos reúnem artigos produzidos por autores e autoras de vários países, o que atesta o vigor e a atualidade da contribuição teórico-prática, deste pernambucano cidadão do mundo. Tais análises intentam verificar quais as contribuições do pensamento freiriano para o campo da comunicação, da educação e do desenvolvimento da sociedade civil, considerando as realidades locais em que foram mobilizadas.
Las Voces que Somos, um enunciado da mídia dialógica indígena para a libertação
Authors: Magallanes-Blanco Claudia
Published: January 2022

Neste artigo, reviso as teorias de Paulo Freire da ação antidialógica e da ação cultural dialógica, bem como a noção de diálogo e enunciados de Bakhtin. Com base nisso, enfoco um projeto de comunicação de mídia indígena no estado de Oaxaca, México, e em um de seus produtos midiáticos que considero um enunciado de mídia. Defendo que os temas centrais do projeto de comunicação e uma série de rádio que os abordam, refletem o diálogo entre os comunicadores indígenas e a realidade atual que enfrentam, que ameaça seus territórios e modos de vida. O diálogo é um componente fundamental de um processo comunicativo que molda nossa compreensão do sistema-mundo e torna as diferenças e desigualdades evidentes.
Duas faces do mesmo CLIL: A integração de conteúdo e língua na formação de professores e em projetos para o ensino de italiano em escolas públicas brasileiras
Authors: Porcellato Adriana Mendes
Published: January 2022

Este estudo foi conduzido no contexto de um programa multicultural para capacitar professores de diferentes disciplinas na rede pública municipal de São Paulo a ofertar projetos de língua italiana aos alunos de suas escolas. Os dados apresentados neste artigo foram coletados durante a preparação didática, em que a abordagem CLIL (Content and Language Integrated Learning), que promove a aprendizagem integrada de língua e conteúdo (cf. COYLE, HOOD e MARSCH, 2010), teve dúplice função: por um lado, as aulas do curso de formação foram elaboradas seguindo essa abordagem; por outro, o CLIL foi um dos conteúdos tratados no curso e influenciou os projetos finais elaborados pelos professores. Analisando as atividades didáticas utilizadas no curso, o diário da formadora, os projetos finais e os questionários respondidos pelos professores, percebeu-se que a implementação da modalidade CLIL exige diversos conhecimentos por parte do docente e, em especial, uma sensibilidade linguística (HE e LIN, 2018) específica que permita identificar pontos de integração entre o conteúdo ensinado e os aspectos linguísticos necessários para a aquisição. As análises mostraram que, durante a preparação didática e com o apoio da formadora, os professores começaram a adquirir, mesmo que só parcialmente, essa sensibilidade. Apesar de apresentar desafios, a abordagem CLIL pode ser um caminho promissor quando aplicada ao contexto de formação de professores e ao ensino da língua italiana.
Inquiries on Cultural Markers in Translation
Authors: Aubert Francis Henrik
Published: January 2022

In descriptive translation studies, the identification of cultural markers brings with it certain theoretical and methodological difficulties: the very conceptualization of the cultural marker; its subcategories, both linguistic and extra-linguistic; the appropriate procedures to carry out its identification. The present essay seeks to map the extent of these difficulties and make a number of proposals, yet to be tested in descriptive practice.
Nossos corpos por nós mesmas: o processo de tradução e adaptação cultural em palimpsesto
Authors: Lima Érica
Published: January 2022

O objetivo deste trabalho é discutir alguns aspectos da tradução do livro Our Bodies, Ourselves, cujo primeiro volume, Nossos corpos por nós mesmas, acaba de ser publicado no Brasil. Para tanto, serão apresentadas as três etapas principais do processo, divididas em camadas. Na primeira, temos a preparação, com reflexão teórica que fundamenta o trabalho de tradução colaborativa e ativista e definição da metodologia adotada. Em seguida, trazemos algumas considerações sobre a tradução propriamente dita e, por fim, apresentamos cinco depoimentos sobre os diferentes impactos que o projeto tem trazido  para as alunas e dos alunos que participaram da tradução. O texto apresenta, ainda, exemplos de adaptação cultural para diferentes países, em especial para realidade brasileira, e algumas conclusões.
Entre a domesticação e a estrangeirização: análise das estratégias de tradução em “Sejamos todos feministas”
Authors: Koglin Arlene , Morales Klee Márcia
Published: January 2022

Este artigo discute as estratégias de tradução empregadas no ensaio ‘Sejamos todos feministas,’ da escritora Chimamanda Adichie, no par linguístico inglês-português brasileiro. Ademais, examina teoricamente as implicações ideológicas das soluções tradutórias adotadas em trechos escolhidos segundo dois parâmetros: estranhamento durante a leitura do texto de chegada e evidência de passagens, no texto fonte, com teor nitidamente ideológico. Baseado nas teorias de Schleiermacher (2007), Venuti (1995) e Niranjana (1992, 2010), partiu-se da hipótese de que o texto de chegada tenderia à domesticação através de apagamentos ou de adaptação de estereótipos descritos pela autora no texto fonte. Nos trechos selecionados, a análise demonstrou que a domesticação ocorreu nos níveis estrutural, lexical, cultural, social, ideológico e político, o que confirma nossa hipótese.
Reconstruyendo el chisme: variedad lingüística y marcadores culturales en la traducción al español mexicano del cuento “O jardim selvagem” de Lygia Fagundes Telles
Authors: Ponce Zyanya Carolina
Published: January 2022

Este artículo tiene como objetivo presentar los desafíos y soluciones de traducción del cuento “O jardim selvagem” de Lygia Fagundes Telles al español mexicano. Al entender el proceso traductorio como una transferencia cultural, realizamos una traducción comentada basándonos en nuestro público meta: discutiendo sobre la variación lingüística y los marcadores culturales. El cuento es construido principalmente por diálogos, lo que nos llevó a una discusión de la noción de dialecto y registro na tradução (Hatim & Mason, 1995). También presentamos aspectos de la cultura brasileña a partir de los marcadores culturales (Azenha, 2006; Aubert, 2006; Reichman & Zavaglia, 2014). La clasificación de los comentarios fue basada en el objetivo principal de la traducción: acercar al público mexicano a la obra de Lygia Fagundes Telles.
Marcadores culturais na tradução de linguagens multimodais
Authors: Aragão Sabrina Moura
Published: January 2022

Este trabalho apresenta uma reflexão acerca da tradução de marcadores culturais presentes nas linguagens multimodais. Nesse sentido, a perspectiva da multimodalidade, que mostra que o sentido é produzido a partir da inter-relação de diferentes modos, ou recursos semióticos, configura-se como uma via de reflexão acerca da tradução de histórias em quadrinhos. Tendo em vista a noção de marcador cultural discutida no âmbito dos Estudos da Tradução, aplicamos tais conceitos à especificidade da linguagem dos quadrinhos e seu processo de tradução. Considerando tais aspectos, defendemos a hipótese de que, além do texto, a imagem também representa marcadores culturais, o que traz implicações e questões específicas acerca da tradução de quadrinhos.
Cultural markers in the Brazilian film O auto da Compadecida and its subtitles in English
Authors: Monteiro Marcela , Zavaglia Adriana
Published: January 2022

This article proposes a typology of translation of cultural markers in subtitles and uses as research material the film O auto da Compadecida (Arraes, 2000) in Brazilian Portuguese and its translation, A dog's will (Magrath, Videolar, 2000). The difficulty that cultural markers generate during various translation processes is evident and is accentuated in audiovisual works, in which different elements converge (text, image, sound design, soundtrack, body language, among others). To contribute to its analysis in this context, we used the concept of cultural marks and markers (Reichmann and Zavaglia, 2014), translational modalities (Aubert, 2006b), and considered translation techniques (Nunes, n.d.) to arrive at the typology presented here, followed by examples and illustrations.
Estudios culturales en América Latina
Authors: Restrepo Eduardo
Published: January 2022

Duas grandes confusões parecem operar, com frequência, nos discursos em torno dos estudos culturais na América Latina. A primeira é a equivalência de estudos culturais e estudos sobre a cultura. A segunda, muito frequente no contexto estadunidense, é misturar sob o rótulo de estudos culturais a produção heterogênea de intelectuais latino-americanos que abordaram assuntos de cultura e poder e a de acadêmicos latino-americanistas das universidades do Norte. Neste artigo se evidenciam os problemas de ambas as confusões e se sublinham algumas de suas nefastas consequências para a articulação de um projeto intelectual e político de estudos culturais na América Latina.
Matriz biológico-cultural da existência humana: fundamentos para aprender, ensinar e educar
Authors: Infante-Malachias Maria Elena
Published: January 2022

Neste ensaio apresentamos uma reflexão sobre a matriz biológico-cultural da existência humana a partir da epistemologia da Biologia do Conhecer, que considera o conhecimento a partir do sujeito que conhece. A matriz que constitui o cerne da Biologia Cultural corresponde à trama relacional onde o homem surge se realiza e conserva o seu viver humano. Nesta trama relacional que se inicia em um processo histórico que teve a sua origem há bilhões de anos, surgem todos os mundos que vivemos como as distintas dimensões do nosso viver cultural. Discutimos a relevância desta perspectiva, que considera ao mesmo tempo a constituição biológica e a cultura, para as relações humanas do ensinar e aprender e destacamos a possibilidade de transformação que surge ao considerar o outro como um legítimo outro na convivência.
A fome antropofágica: utopias e contradições
Authors: Filgueiras Fernanda Oliveira , Leonel Mauro de Mello
Published: January 2022

O Modernismo no Brasil significou um marco, que anunciou o fim de um período cultural caracterizado pelo legado e pelo conservadorismo. O Movimento Antropofágico foi a síntese artística e intelectual dessas reflexões. Este trabalho se propõe a discutir as contribuições e controvérsias deixadas pelo movimento no contexto de urbanização e cosmopolitismo em que ele emergiu na cidade de São Paulo.
Ethnical Afro Tourism in Brazil
Authors: Godoi Luiz Gonzaga , Panosso Netto Alexandre
Published: January 2022

O artigo desenvolve uma discussão teórica sobre o turismo étnico afro no Brasil. A temática somente recentemente tem merecido a devida atenção dos estudiosos, motivo pelo qual se justifica a abordagem. Os objetivos são três: 1) revisar a história das culturas afros no Brasil; 2) identificar as forças que garantem o respeito a essas identidades e; 3) analisar como os destinos afro devem ser trabalhados neste contexto. A metodologia empregada é a revisão teórica dos textos que abordam a cultura afro brasileira, tendo como pano de fundo da discussão os delineamentos dos estudos culturais. Conclui-se que o produto turístico com base na cultura afro é um produto viável no Brasil, porém deve primar pelos quesitos de respeito, alteridade, ética e valorização de todas as culturas envolvidas no processo.
Tobacco Consumption and High‐Sensitivity Cardiac Troponin I in the General Population: The HUNT Study
Authors: Skranes Julia Brox , Lyngbakken Magnus Nakrem , Hveem Kristian , Røsjø Helge , Omland Torbjørn
Published: January 2022

Background

Cardiac troponins represent a sensitive index of subclinical myocardial injury and are associated with increased risk of cardiovascular events in the general population. Despite positive associations with cardiovascular risk of both cardiac troponins and cigarette smoking, concentrations of cardiac troponin I measured by high‐sensitivity assays (hs‐cTnI) are paradoxically lower in current smokers than in never‐smokers. The impact of smoking intensity and time from smoking cessation on hs‐cTnI remains unknown.

Methods and Results

hs‐cTnI concentrations were measured in 32028 subjects free from cardiovascular disease enrolled in the prospective, population‐based HUNT (Trøndelag Health Study). Tobacco habits were self‐reported and classified as never (n=14 559), former (n=14 248), and current (n=3221) smokers. Current smokers exhibited significantly lower concentrations of hs‐cTnI than never‐smokers (
P
<0.001). In adjusted models, both current smoking (−17.3%; 95% CI, −20.6 to −13.9%) and former smoking (−6.6%; 95% CI, −8.7 to −4.5%) were associated with significantly lower hs‐cTnI concentrations. Among former smokers, higher smoking burden (>10 pack‐years) were associated with lower concentrations of hs‐cTnI. Time since smoking cessation was associated with increasing concentrations of hs‐cTnI in a dose‐dependent manner (
P
for trend<0.001), and subjects who quit smoking >30 years ago had concentrations of hs‐cTnI comparable with those of never‐smokers.

Conclusions

In the general population, both current and former cigarette smoking is associated with lower concentrations of hs‐cTnI. In former smokers, there was a dose‐response relationship between pack‐years of smoking, and hs‐cTnI. Time since smoking cessation was associated with increasing concentrations of hs‐cTnI, indicating a continuum of hs‐cTnI from current smoker to never‐smokers.
Thinking across Frames – Temporally Extended Consciousness and the Animation Timeline
Authors: Buchanan Andrew
Published: January 2022

This article explores ways in which animation production technologies (including pre-cinema, film, and digital tools) have evolved as a system that abstracts time, primarily through its spatialization. This abstraction necessitates certain assumptions about the nature of time, including its linearity and directionality. Animation technologies have evolved so as to support various modes of temporally extended consciousness; an animator’s craft thinks and works through time. Embedded within digital production technologies, the animator is faced with a new philosophical instrument: the animation timeline. The main timeline utility in most animation software adopts a linear, mechanical model of time with the individual frame as the base unit. However, digital animation timeline can also complicate the spatialized temporal dimension, as the timeline is also embedded within animated objects in motion paths and other interface elements . As animated objects always exist through time, not merely within individual frames, the animation software tools for working with time both confine and unlock opportunities for working with time.
Prior’s Turn to Medieval Logic
Authors: Jakobsen David
Published: January 2022

The peculiar aspect of medieval logic, that the truth-value of propositions changes with time, gradually disappeared as Europe exited the Renaissance. In modern logic, it was assumed by W.V.O. Quine that one cannot appreciate modern symbolic logic if one does not take it to be tenseless. A.N. Prior’s invention of tense-logic challenged Quine’s view and can be seen as a turn to medieval logic. However, Prior’s discussion of the philosophical problems related to quantified tense-logic led him to reject essential aspects of medieval logic. This invites an evaluation of Prior’s formalisation of tense-logic as, in part, an argument in favour of the medieval view of propositions. This article argues that Prior’s turn to medieval logic is hampered by his unwillingness to accept essential medieval assumptions regarding facts about objects that do not exist. Furthermore, it is argued that presentists should learn an important lesson from Prior’s struggle with accepting the implications of quantified tense-logic and reject theories that purport to be presentism as unorthodox if they also affirm Quine’s view on ontic commitment. In the widest sense: philosophers who, like Prior, turn to the medieval view of propositions must accept a worldview with facts about individuals that, in principle, do not supervene (present tense) on being, for they do not yet exist.
The Response of Creative Class Members to Regions Vying to Attract Them With Subsidies
Authors: Batabyal Amitrajeet A. , Beladi Hamid
Published: January 2022

There are no theoretical studies in regional science that examine which region to locate in from the standpoint of a creative class member, given that the pertinent regional authorities (RAs) are competing among themselves to attract the creative class using subsidies. This gap provides the motivation for our paper. This paper’s contribution is that it is the first to theoretically study the regional location choice of creative class members when the RAs of the locations in which they might locate are using subsidies to attract them. Specifically, a knowledge good producing creative class member must decide which of two regions ( A or B) to locate his plant in. This good is produced using a Cobb–Douglas function with creative and physical capital. We analyze plant location in four cases. In the benchmark case, we show that the representative creative class member ought to locate his plant in the less expensive region B. Next, we show that a small subsidy to creative capital by region A switches the plant location decision from region B to A. Finally, when both regions grant identical subsidies to creative capital, the representative creative class member is indifferent between locating in regions A and B. So, for identical subsidies to affect the plant location decision, they are better targeted to physical and not to creative capital.

JEL Codes: R11, R58
An Email Coaching Option Increases Participant Program Utilization and Coach Productivity
Authors: Garrels Samantha , Macias Elizabeth , Bender Eric , Spoonheim Joel , Kottke Thomas E.
Published: January 2022

Purpose

To assess impact of adding an email option to phone-based coaching on the number of coaching sessions completed.

Design

Retrospective analysis of a change in program design.

Setting

A health plan health and wellness coaching service.

Subjects

Six thousand six hundred twenty four individuals who scheduled at least one coaching session.

Intervention

Adding an email option to phone coaching May 1 to August 31, 2020.

Measures

Association of a participant using an email coaching option with completing 3 coaching sessions; overall number of participants completing 3 coaching sessions when email is offered; participant satisfaction rates; and, average number of participants coached per coach by month.

Analysis

χ2; linear and logistic regression with gender, age, and education as covariates.

Results

When we offered email coaching, 29.6% of eligible participants used the option, and compared with the same months the prior year, the proportion of participants completing 3 sessions during those months was higher (73% vs 67%). ( P < .0001) 96.5% of participants who used email, vs 92.0% who did not, completed 3 sessions before their employer’s benefit qualifying deadline. ( P < .0001) More than 85% who responded to the email coaching survey expressed satisfaction. On average, each coach served 43% (486 vs 340) more participants per month when we offered email coaching. ( P < .0001).

Conclusion

Adding email coaching to phone coaching can increase program utilization by individuals who use email, increase overall program utilization, generate high levels of participant satisfaction, and increase the number of participants served per coach.
India’s Fight against the COVID-19 Pandemic: Lessons and the Way Forward
Authors: Sharma Shalendra D.
Published: January 2022

In early 2020, when the COVID-19 pandemic was indiscriminately spreading around the world, the seeming ability of India, the world’s second most populous country (with over 1.3 billion people), to contain the virus within its borders and keep COVID-19 infection and mortality rates low relative to population size was seen as miraculous. However, the miracle ended when the ‘second-wave’ hit India in April 2021. On 1 May 2021, India became the first country in the world to record more than 400,000 coronavirus infections in a single day. This exponential rise in COVID-19 cases started on 28 April 2021 when India recorded 379,459 new COVID-19 cases and 3,647 deaths. This marked the eighth straight day of more than 300,000 cases a day—making India the second-highest COVID-19 case count in the world (over 20 million) with over 25 per cent of the global deaths from COVID. The following examines India’s fight against the pandemic, the failure to contain the second wave, the lessons learned and the way forward.
What Counts as Evidence in Child Welfare Research?
Authors: Tajima Emiko A. , Day Angelique G. , Kanuha V. Kalei , Rodriquez-JenKins Jessica , Pryce Jessica A.
Published: January 2022

In this commentary, we respond to Barth and colleagues and critique their premise that Western-based research with population-level administrative data is the best and only valid evidence on which to base child welfare policy and practice changes. We offer an alternative viewpoint on what forms of evidence should be brought to bear as we consider re-envisioning the child welfare system, highlighting the importance of lived experience and the need to consider the evidence regarding all marginalized racial and ethnic groups. We argue that evidence should represent the perspectives of those with lived experience and that collaborative child welfare research can strengthen the validity of analyses and interpretations. We hold that Barth et al. ask and answer the wrong questions. We press for deeper critical reflection, a more nuanced intersectional lens, and urgent action to address structural and institutional racism in the child welfare system.
Virtual Bronchoscopy-Guided Transbronchial Biopsy Simulation Using a Head-Mounted Display: A New Style of Flexible Bronchoscopy
Authors: Okachi Shotaro , Ito Takayasu , Sato Kazuhide , Iwano Shingo , Shinohara Yuka , Itoigawa Hideyuki , Hashimoto Naozumi
Published: January 2022

Background/need. The increases in reference images and information during bronchoscopy using virtual bronchoscopic navigation (VBN) and fluoroscopy has potentially created the need for support using a head-mounted display (HMD) because bronchoscopists feel difficulty to see displays that are at a distance from them and turn their head and body in various directions. Methodology and device description. The binocular see-through Moverio BT-35E Smart Glasses can be connected via a high-definition multimedia interface and have a 720p high-definition display. We developed a system that converts fluoroscopic (live and reference), VBN, and bronchoscopic image signals through a converter and references them using the Moverio BT-35E. Preliminary results. We performed a virtual bronchoscopy-guided transbronchial biopsy simulation using the system. Four experienced pulmonologists performed a simulated bronchoscopy of 5 cases each with the Moverio BT-35E glasses, using bronchoscopy training model. For all procedures, the bronchoscope was advanced successfully into the target bronchus according to the VBN image. None of the operators reported eye or body fatigue during or after the procedure. Current status. This small-scale simulation study suggests the feasibility of using a HMD during bronchoscopy. For clinical use, it is necessary to evaluate the safety and usefulness of the system in larger clinical trials in the future.
Lifetime and Aging Degradation Prognostics for Lithium-ion Battery Packs Based on a Cell to Pack Method
Authors: Che Yunhong , Deng Zhongwei , Tang Xiaolin , Lin Xianke , Nie Xianghong , Hu Xiaosong
Published: January 2022

Aging diagnosis of batteries is essential to ensure that the energy storage systems operate within a safe region. This paper proposes a novel cell to pack health and lifetime prognostics method based on the combination of transferred deep learning and Gaussian process regression. General health indicators are extracted from the partial discharge process. The sequential degradation model of the health indicator is developed based on a deep learning framework and is migrated for the battery pack degradation prediction. The future degraded capacities of both battery pack and each battery cell are probabilistically predicted to provide a comprehensive lifetime prognostic. Besides, only a few separate battery cells in the source domain and early data of battery packs in the target domain are needed for model construction. Experimental results show that the lifetime prediction errors are less than 25 cycles for the battery pack, even with only 50 cycles for model fine-tuning, which can save about 90% time for the aging experiment. Thus, it largely reduces the time and labor for battery pack investigation. The predicted capacity trends of the battery cells connected in the battery pack accurately reflect the actual degradation of each battery cell, which can reveal the weakest cell for maintenance in advance.
Exploring the transportome of the biosurfactant producing yeast Starmerella bombicola
Authors: Claus Silke , Jezierska Sylwia , Elbourne Liam D. H. , Van Bogaert Inge
Published: January 2022

Starmerella bombicola is a non-conventional yeast mainly known for its capacity to produce high amounts of the glycolipids ‘sophorolipids’. Although its product has been used as biological detergent for a couple of decades, the genetics of S. bombicola are still largely unknown. Computational analysis of the yeast’s genome enabled us to identify 254 putative transporter genes that make up the entire transportome. For each of them, a potential substrate was predicted using homology analysis, subcellular localization prediction and RNA sequencing in different stages of growth. One transporter family is of exceptional importance to this yeast: the ATP Binding Cassette (ABC) transporter Superfamily, because it harbors the main driver behind the highly efficient sophorolipid export. Furthermore, members of this superfamily translocate a variety of compounds ranging from antibiotics to hydrophobic molecules. We conducted an analysis of this family by creating deletion mutants to understand their role in the export of hydrophobic compounds, antibiotics and sophorolipids. Doing this, we could experimentally confirm the transporters participating in the efflux of medium chain fatty alcohols, particularly decanol and undecanol, and identify a second sophorolipid transporter that is located outside the sophorolipid biosynthetic gene cluster.
Premature mortality attributable to COVID-19: potential years of life lost in 17 countries around the world, January–August 2020
Authors: Ugarte Maider Pagola , Achilleos Souzana , Quattrocchi Annalisa , Gabel John , Kolokotroni Ourania , Constantinou Constantina , Nicolaou Nicoletta , Rodriguez-Llanes Jose Manuel , Huang Qian , Verstiuk Olesia , Pidmurniak Nataliia , Tao Jennifer Wenjing , Burström Bo , Klepac Petra , Erzen Ivan , Chong Mario , Barron Manuel , Hagen Terje P. , Kalmatayeva Zhanna , Davletov Kairat , Zucker Inbar , Kaufman Zalman , Kereselidze Maia , Kandelaki Levan , Le Meur Nolwenn , Goldsmith Lucy , Critchley Julia A. , Pinilla Maria Angelica , Jaramillo Gloria Isabel , Teixeira Domingos , Goméz Lara Ferrero , Lobato Jackeline , Araújo Carolina , Cuthbertson Joseph , Bennett Catherine M. , Polemitis Antonis , Charalambous Andreas , Demetriou Christiana A. ,   On behalf of the C-MOR consortium
Published: January 2022

Background

Understanding the impact of the burden of COVID-19 is key to successfully navigating the COVID-19 pandemic. As part of a larger investigation on COVID-19 mortality impact, this study aims to estimate the Potential Years of Life Lost (PYLL) in 17 countries and territories across the world (Australia, Brazil, Cape Verde, Colombia, Cyprus, France, Georgia, Israel, Kazakhstan, Peru, Norway, England & Wales, Scotland, Slovenia, Sweden, Ukraine, and the United States [USA]).

Methods

Age- and sex-specific COVID-19 death numbers from primary national sources were collected by an international research consortium. The study period was established based on the availability of data from the inception of the pandemic to the end of August 2020. The PYLL for each country were computed using 80 years as the maximum life expectancy.

Results

As of August 2020, 442,677 (range: 18–185,083) deaths attributed to COVID-19 were recorded in 17 countries which translated to 4,210,654 (range: 112–1,554,225) PYLL. The average PYLL per death was 8.7 years, with substantial variation ranging from 2.7 years in Australia to 19.3 PYLL in Ukraine. North and South American countries as well as England & Wales, Scotland and Sweden experienced the highest PYLL per 100,000 population; whereas Australia, Slovenia and Georgia experienced the lowest. Overall, males experienced higher PYLL rate and higher PYLL per death than females. In most countries, most of the PYLL were observed for people aged over 60 or 65 years, irrespective of sex. Yet, Brazil, Cape Verde, Colombia, Israel, Peru, Scotland, Ukraine, and the USA concentrated most PYLL in younger age groups.

Conclusions

Our results highlight the role of PYLL as a tool to understand the impact of COVID-19 on demographic groups within and across countries, guiding preventive measures to protect these groups under the ongoing pandemic. Continuous monitoring of PYLL is therefore needed to better understand the burden of COVID-19 in terms of premature mortality.
RETRACTED ARTICLE: The LMCD1-AS1/miR-526b-3p/OSBPL5 axis promotes cell proliferation, migration and invasion in non-small cell lung cancer
Authors: Hu Rui , Yu Yankai , Wang Haining
Published: January 2022

Purpose

To explore the specific role and regulatory mechanism of oxysterol binding protein like 5 (OSBPL5) in non-small cell lung cancer (NSCLC).

Methods and results

Quantitative real-time polymerase chain reaction (qRT-PCR) analysis demonstrated that OSBPL5 expression was notably elevated in NSCLC tissues and cell lines, and Kaplan–Meier analysis manifested that high OSBPL5 expression was closely related to the poor prognosis of NSCLC patients. Besides, according to the results from western blot analysis, cell counting kit-8, EdU and Transwell assays, knockdown of OSBPL5 suppressed NSCLC cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) process. Additionally, by performing qRT-PCR analysis, luciferase reporter and RNA pull-down assays, we verified that OSBPL5 was a downstream target of miR-526b-3p and long noncoding RNA (lncRNA) LMCD1-AS1 served as a sponge for miR-526b-3p. Moreover, from rescue assays, we observed that OSBPL5 overexpression offset LMCD1-AS1 knockdown-mediated inhibition in cell proliferation, migration, invasion and EMT in NSCLC.

Conclusions

This paper was the first to probe the molecular regulatory mechanism of OSBPL5 involving the LMCD1-AS1/miR-526b-3p axis in NSCLC and our results revealed that the LMCD1-AS1/miR-526b-3p/OSBPL5 axis facilitates NSCLC cell proliferation, migration, invasion and EMT, which may offer a novel therapeutic direction for NSCLC.
Acacetin inhibits invasion, migration and TGF-β1-induced EMT of gastric cancer cells through the PI3K/Akt/Snail pathway
Authors: Zhang Guangtao , Li Zhaoyan , Dong Jiahuan , Zhou Weili , Zhang Zhanxia , Que Zujun , Zhu Xiaohong , Xu Yan , Cao Nida , Zhao Aiguang
Published: January 2022

Background

Epithelial-to-mesenchymal transition (EMT) is a pivotal cellular phenomenon involved in tumour metastasis and progression. In gastric cancer (GC), EMT is the main reason for recurrence and metastasis in postoperative patients. Acacetin exhibits various biological activities. However, the inhibitory effect of acacetin on EMT in GC is still unknown. Herein, we explored the possible mechanism of acacetin on EMT in GC in vitro and in vivo.

Methods

In vitro, MKN45 and MGC803 cells were treated with acacetin, after which cell viability was detected by CCK-8 assays, cell migration and invasion were detected by using Transwell and wound healing assays, and protein expression was analysed by western blots and immunofluorescence staining. In vivo, a peritoneal metastasis model of MKN45 GC cells was used to investigate the effects of acacetin.

Results

Acacetin inhibited the proliferation, invasion and migration of MKN45 and MGC803 human GC cells by regulating the expression of EMT-related proteins. In TGF-β1-induced EMT models, acacetin reversed the morphological changes from epithelial to mesenchymal cells, and invasion and migration were limited by regulating EMT. In addition, acacetin suppressed the activation of PI3K/Akt signalling and decreased the phosphorylation levels of TGF-β1-treated GC cells. The in vivo experiments demonstrated that acacetin delayed the development of peritoneal metastasis of GC in nude mice. Liver metastasis was restricted by altering the expression of EMT-related proteins.

Conclusion

Our study showed that the invasion, metastasis and TGF-β1-induced EMT of GC are inhibited by acacetin, and the mechanism may involve the suppression of the PI3K/Akt/Snail signalling pathway. Therefore, acacetin is a potential therapeutic reagent for the treatment of GC patients with recurrence and metastasis.
Stakeholder views of the development of a clinical quality registry for interventional radiology: a qualitative study
Authors: Haig Ylva , Feiring Eli
Published: January 2022

Background

Clinical quality registries (CQRs) can likely improve quality in healthcare and research. However, studies indicate that effective use of CQRs is hindered by lack of engagement and interest among stakeholders, as well as factors related to organisational context, registry design and data quality. To fulfil the potential of CQRs, more knowledge on stakeholders’ perceptions of the factors that will facilitate or hamper the development of CQRs is essential to the more appropriate targeting of registry implementation and the subsequent use of the data. The primary aim of this study was to examine factors that can potentially affect the development of a national CQR for interventional radiology in Norway from the perspective of stakeholders. Furthermore, we wanted to identify the intervention functions likely to enable CQR development. Only one such registry, located in Sweden, has been established. To provide a broader context for the Norwegian study, we also sought to investigate experiences with the development of this registry.

Methods

A qualitative study of ten Norwegian radiologists and radiographers using focus groups was conducted, and an in-depth interview with the initiator of the Swedish registry was carried out. Questions were based on the Capability, Opportunity and Motivation for Behaviour Model and the Theoretical Domains Framework. The participants’ responses were categorised into predefined themes using a deductive process of thematic analysis.

Results

Knowledge of the rationale used in establishing a CQR, beliefs about the beneficial consequences of a registry for quality improvement and research and an opportunity to learn from a well-developed registry were perceived by the participants as factors facilitating CQR development. The study further identified a range of development barriers related to environmental and resource factors (e.g., a lack of organisational support, time) and individuallevel factors (e.g., role boundaries, resistance to change), as well as several intervention functions likely to be appropriate in targeting these barriers.

Conclusion

This study provides a deeper understanding of factors that may be involved in the behaviour of stakeholders regarding the development of a CQR. The findings may assist in designing, implementing and evaluating a methodologically rigorous CQR intervention.