bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Syariah Compliance, Promosi dan Teknologi Terhadap Reputasi Bank Syariah Indonesia dan Dampaknya terhadap Loyalitas Nasabah
Authors: Siregar Ita Nurliana
Published: August 2022

Penelitian ini bertujuan untuk mengetahui pengaruh Syariah Compliance, Promosi dan Teknologi terhadap Reputasi Bank Syariah Indonseia Cabang Gatot Subroto dan Dampaknya terhadap Loyalitas Nasabah secara persial dan secara bersamaan. Jenis data yang digunakan dalam penelitian ini adalah data kuantitatif. Pengumpulan data dilakukan dengan cara Angket (Koesioner), Dokumentasi dan Wawancara. Sampel dalam penelitian ini berjumlah 100 orang. Analisis data yang digunakan adalah analisis Deskriptif, Uji Variabel, Uji Reliabilitas, Analisis Regresi Linier Berganda, Uji T, Uji F, dan Analisis Koefisien Determinasi dan Path Analysis. Secara langsung syariah compliance melalui reputasi mempunyai pengaruh signifikan terhadap loyalitas nasabah, secara tidak langsung promosi melalui reputasi mempunyai pengaruh signifikan terhadap loyalitas nasabah dan secara tidak langsung teknologi melalui reputasi mempunyai pengaruh signifikan terhadap loyalitas nasabah.
Platelet-rich plasma treatment in patients with refractory thin endometrium and recurrent implantation failure: A comprehensive review
Authors: Kim Min Kyoung , Song Haengseok , Lyu Sang Woo , Lee Woo Sik
Published: August 2022

Refractory thin endometrium and recurrent implantation failure are among the most challenging infertility-related factors hindering successful pregnancy. Several adjuvant therapies have been investigated to increase endometrial thickness and the pregnancy rate, but the treatment effect is still minimal, and for many patients, these treatment methods can be quite costly and difficult to approach. Platelet-rich plasma (PRP) is an autologous concentration of platelets in plasma and has recently been elucidated as a better treatment option for these patients. PRP is rich in cytokines and growth factors, which are suggested to exert a regenerative effect at the level of the injured tissue. Another advantage of PRP is that it is easily obtained from the patient’s own blood. We aimed to review the recent findings of PRP therapy used for patients with refractory thin endometrium and recurrent implantation failure.
On the Cost of Suppressing Volume for Encrypted Multi-maps
Authors: Ando Megumi , George Marilyn
Published: August 2022

Structured encryption (STE) schemes allow a client to store sensitive data on a semi-trusted remote server and query the data. STE schemes strike a balance between privacy and efficiency by leaking some information to the server. In particular, many STE schemes leak the volume pattern i.e., response lengths, and the query equality pattern i.e., if any queries are repeated. Recently discovered leakage-abuse attacks demonstrate that leaking the volume pattern can be unsafe; that is, the server can reconstruct parts of the database from this leakage. To address this leakage, Kamara and Moataz proposed a novel multi-map encryption scheme, AVLH, that hides query volumes by padding responses with parts of other responses (Eurocrypt 2019). AVLH was shown to be more storage-efficient than the naive approach to pad responses with dummy values to reach the maximum response length. Subsequently, Patel et al. provided an even more efficient volume-hiding multimap scheme, dprfMM (CCS 2019). Despite these advances, the costs of fully suppressing query volumes are still unclear. In this paper, we provide the first lower bounds on STE schemes for multi-maps that leak at most the query equality pattern. Surprisingly, we find that in many cases, such STE schemes cannot be more storage-efficient than naively padding to the maximum length.
Neural Fuzzy Extractors: A Secure Way to Use Artificial Neural Networks for Biometric User Authentication
Authors: Jana Abhishek , Paudel Bipin , Sarker Md Kamruzzaman , Ebrahimi Monireh , Hitzler Pascal , Amariucai George T
Published: August 2022

Powered by new advances in sensor development and artificial intelligence, the decreasing cost of computation, and the pervasiveness of handheld computation devices, biometric user authentication (and identification) is rapidly becoming ubiquitous. Modern approaches to biometric authentication, based on sophisticated machine learning techniques, cannot avoid storing either trained-classifier details or explicit user biometric data, thus exposing users’ credentials to falsification. In this paper, we introduce a secure way to handle user-specific information involved with the use of artificial neural networks for biometric authentication. Our proposed architecture, called a Neural Fuzzy Extractor (NFE), allows the coupling of pre-existing classifiers with fuzzy extractors, through an artificial-neuralnetwork-based buffer called an expander, with minimal or no performance degradation. The NFE thus offers all the performance advantages of modern deep-learningbased classifiers and all the security of standard fuzzy extractors. We demonstrate the NFE retrofit of a few classic artificial neural networks, for simple biometric authentication scenarios.
On the Feasibility of Linking Attack to Google/Apple Exposure Notification Framework
Authors: Nomoto Kazuki , Akiyama Mitsuaki , Eto Masashi , Inomata Atsuo , Mori Tatsuya
Published: August 2022

Digital contact-tracing (DCT) applications have been installed on more than 188 M smartphones worldwide as an effective mechanism for monitoring contact with COVID-19 infected individuals. DCT is promising not only for COVID-19, but also for preparing for a possible future large-scale pandemic. The DCT framework is unique in that it combines Bluetooth Low Energy (BLE) communications with cryptography techniques to track exposure on a large scale while protecting user privacy. The objective of this study is to assess the risk of the linking attack to the DCT frameworks; i.e., linking individuals to the identifiers contained in BLE broadcast frames that are supposed to be anonymized. Specifically, we target Google/Apple’s Exposure Notification (GAEN), which is the representative implementation of DCT. Our extensive experiments demonstrate that passively collected rolling proximity identifiers (RPIs) contained in the BLE frames can be linked to face photos which could lead to the exposure of privacy information with high accuracy, including infection status. We also demonstrate that an attacker with a few number of devices can correctly link RPIs and the images of the target person with a success rate of 86% at a rate of 5,000 users per hour. Based on these results, we propose countermeasures to reduce the inherent privacy risk of the GAEN framework.
Replay (Far) Away: Exploiting and Fixing Google/Apple Exposure Notification Contact Tracing
Authors: Ellis Christopher , Wen Haohuang , Lin Zhiqiang , Arora Anish
Published: August 2022

Digital contact tracing offers significant promise to help reduce the spread of SARS-CoV-2 and other viruses. Google and Apple joined together in 2020 to create the Google/Apple Exposure Notification (GAEN) framework to determine encounters with anonymous users later diagnosed COVID-19 positive. However, as GAEN lacks geospatial awareness, it is susceptible to geographically distributed replay attacks. Anonymous, low-cost, crowd-sourced replay attack networks deployed by malicious actors (or far away nation-state attackers) who utilize malicious (or innocent) users’ smartphones to capture and replay GAEN advertisements can drastically increase false-positive rates even in areas that otherwise exhibit low positivity rates. In response to this powerful replay attack, we introduce GAEN+ , a solution that enhances GAEN with geospatial awareness while maintaining user privacy, and demonstrate its ability to effectively prevent geographically distributed replay attacks.
Organizational innovation and ports logistiques: The case of Agadir port
Authors: SERGHINI Meryem
Published: August 2022

The aim of this work is to study the contribution of organizational innovation to the achievement of the logistical performance of the port of Agadir. The results of this research highlight three areas of innovative organizational practices: structure, IS, and Human Resources. The port of Agadir has an interest in adopting management practices. This fact is observed in our qualitative study where the significant impact of organizational innovation on the logistics performance of the port is positive. The mobilization of Network theory recognizes that the managerial approach is a strategic tool for the adoption of innovative organizational practices and not as a source of costs (Michel Callon and Bruno Latour (2016).
Narrow Concept of Accountability in Public Sector Expenditure: Measuring Accountability Proportionately and Progressively
Authors: I Dewa Agung Gede Manu  , I Made Subawa2  , Putu Gede Arya Sumerta Yasa  , Desak Putu Dewi Kasih
Published: August 2022

Accountability is one of the main elements of the realization of good governance which is currently being pursued in Indonesia. The government is asked to report the results of the programs that have been implemented so that the public can assess whether the government has worked economically, efficiently and effectively. Accountability can be seen from an accounting perspective, a functional perspective and an accountability system perspective. This Scientific Journal uses normative legal research and uses a statutory approach and a legal concept approach. the development of the public service paradigm from a broad concept of accountability to a narrow concept of accountability in public sector procurement spending that uses providers of goods and services, both as business entities and individuals, is done through the selection of providers of goods and services. The power to set policies is exercised by the legislature, specifically in the policy of setting the state budget, known as budget rights. Meanwhile, the executive power in the field of state finances is known as the general power for managing state finances. Based on this, the concept of governance which emphasizes the mechanism in carrying out functions by actors involved in certain sectors has not shown a certain mechanism, as well as the principle of accountability which is an element of governance that is still an accountability concept with general evaluative character (umbrella concept). The very broad, general and evaluative, is very difficult to define practically and empirically because there are no operational standards for accountable behavior.
Residential Housing Satisfaction in Public Housing Estates in Calabar, Cross River State, Nigeria
Authors: Ajom Simon K. , Mfon Ifiok Enobong , Moses Ndifreke Etim , Eteng Salvation
Published: August 2022

The paper examined the satisfaction level of residents in public housing estates in Calabar, Cross River State Nigeria. The variables for establishing the satisfaction level were broadly categorized into three (3); housing location, physical facilities and environmental factors. However, five (5) public residential estates were selected for data collection. Data were elicited using 100 copies of questionnaire. Questionnaire were given to household heads and all were returned and used for analysis. Analysis were carried out using frequencies and relative satisfaction index (RSI). With RSI, the satisfaction level of the residents with the housing area was determined. Furthermore, a five point likert scale was adopted in collecting data from residents within the housing area. Findings revealed that the residents of public housing estates were not completely satisfied with the housing environments. For instance, it was shown that the residents were fairly satisfied with the housing location. Similar results were obtained on both the environmental and physical facilities. Variables such as proximity to service, waste disposal/management, water supply among others were observed to influence the level of satisfaction of residents with the housing area. It was also observed that facilities and amenities were drastically deteriorating within public residential estates and the aesthetic quality of the housing environment is facing serious distortion. Based on these observations, it was suggested that facilities and amenities that go along to making housing environments habitable and conducive be provided and deteriorating facilities be upgraded. There should also be regular renewal of the housing environments in public estates to avoid deterioration and dilapidation of structures within the housing environment.

 

Keywords: Housing environment, housing location, level of satisfaction, physical facilities, residential housing.
Scientometric Analysis and Collaboration Trends of Published Literature by State Universities from West Bengal
Authors: RAHAMAN JIAUR , Sadik Batcha
Published: August 2022

The study examines the analysis of research output by the Universities of West Bengal from 2002 to 2021. Journal articles are the most preferred form of publication type of documents by the Universities of West Bengal. It shows the highest RGR value among seven universities is obtained by Vidyasagar University in the year 2021 and the lowest value is obtained by the University of Calcutta in the year 2021. The study used Domestic Collaboration and International Collaboration and it shows the highest paper 11529 (38.38%) was published at the domestic level and international level 3140 (43.87%) by Jadavpur University. It found that 16.82 % of the total publications are open access research articles with 6255. It is quite interesting to know that Jadavpur University has a significant lead towards encouraging the researcher to publish in open access journals with 33.78%. The most productive author is Subhadeep Das, Department of Life Sci. & Biotechnology, Jadavpur University with 908 articles ranked in first place among the universities studied.
Effect of Scaffolding Teaching Method on Students’ Academic Achievement in Mathematics
Authors: Faheem Khan  , Aqsa Ahmad  , Memoona Gul  , Shakeel Hussain  , Sobia yousaf
Published: August 2022

The current research focuses on the scaffolding instructional technique in improving students’ understanding level in the subject of mathematics.  The study was experimental in nature and thereby experiment was conducted at Government School Daraban Kalan, District Dera Ismail Khan, Khyber PakhtunKhwa. Two groups are formed of 10th grade students on the basis on pre-test score. Twenty five (25) students were randomly assigned to control group whereas 25 students assigned randomly to experimental group. Control group were taught to conventional style of teaching while treatment group was taught by using scaffolding instructional approach. Pretest and Posttest was developed from 10th grade mathematics syllabus. The result of the study reveals that students secured high marks in experimental group as compared to control group. The study concluded that scaffolding instructional strategy enhances the students learning in academic achievement.
Women and Emotional Variabilities: Reading of the Delicate Complexes ‘Subjecting Asha-Binodini’ in Tagore’s Chokher Bali
Authors: Roy Suparna
Published: August 2022

Women have often been deployed from many social representational practices for their absently marked subject positions; they have been made to function as the ‘subjects’ of absent political representations. Feminism as such had no pinpointed strategy of commencing in Indian geography, except for personalities protesting against social rules to demand equal spaces for the women. In the field of Indian English Literature that can be considered as feminist writings, we indeed have remarkable contributing personalities like Mahasweta Devi, Jhumpa Lahiri, and many more. Culture functions as a foundationalist fable in shaping identities and sustaining them, and such Bengali culture has also created women as a separate entity definable by few ‘fixed’ characteristics of linguistic absence. In this regard Judith Butler beautifully stated that “Women are the sex which is not “one”. Within…a phallogocentric language, women constitute the unrepresentable…women represent the sex that cannot be thought, a linguistic absence and opacity” (Butler, 13). Rabindranath Tagore’s literary pieces has often been called feminist works for they constructively deconstructed the intricate cultural stigmas. Tagore’s presentation of women was both subversive and culturally vibrant, few dominated; while few were dominated, which my paper would try discerning by the application of queer-post-structuralist feminist theory.
Pela Gandong local wisdom as multicultural education model after the Ambon Conflict
Authors: Hasudungan Anju Nofarof
Published: August 2022

The purpose of this study is to describe how Pela Gandong as a model of multicultural education has been implemented between the State Junior High School (SMPN) 9 Ambon City and the State Junior High School (SMPN) 4 Salahutu Liang, Central Maluku Regency. The Ambon conflict became a very valuable lesson for the Indonesian people, especially the Ambonese-Maluku people. That the diversity that has been bestowed must be managed properly and is a reality of life. The Ambon conflict is the largest civil conflict based on ethnicity, religion, race and ethnicity (SARA) after the fall of the Suharto government on May 21, 1998. After the Ambon conflict ended, various parties began to think about how to do peacebuilding so that similar conflicts did not happen again. One of them is implementing multicultural education based on the local wisdom values of Pela Gandong. During the Ambon conflict resolution, Pela Gandong's local wisdom became the medium. The research method used is descriptive qualitative with a case study approach. Data was collected by means of literature study, interviews, observation, and document analysis. The results show that Pela Gandong contains multicultural values that have been built by the ancestors of the Maluku people, and is currently uniting Muslim and Christian students with a local cultural approach. The implementation is done by transforming Pela Gandong values in schools and teacher exchanges. Then jointly held; scouting activities, camping, Christmas, iftar, Sports and Arts Week. Both schools were also part of the 2013 film Provocateur of Peace as a campaign for peace and the spread of multicultural values.
Numerical study of convective heat transfer and of turbulent forced of differents Nanofluids in channel
Authors: Bekhti MOHAMMED , Rachid Saim
Published: August 2022

In this study, the flow field and heat transfer of differents nanofluids (AL2O3, CuO, SiO2, ZnO), turbulent forced convection in a channel. The surface of the channel is hot Th= 310 K. Simulations are carried out for constant water Prandtl number of 6.99, Reynolds numbers from 20,000, 30,000, 40,000, 50,000 to 60,000, nanoparticles volume fractions of 0, 0.01, 0.02, 0.03, 0.04 and nanoparticles diameter of 30 nm. The finite volume method and SIMPLE algorithm and k-e are utilized to solve the governing equations numerically. The numerical results showed that with enhancing Reynolds numbers and volume fractions, average Nusselt number increases.
The Basic Concept of Cyber Crime
Authors: Goni Osman , Md. Haidar Ali  , Showrov  , Md. Mahbub Alam  , Md. Abu Shameem
Published: August 2022

Cyber Crime is a common phenomenon in the world. Cyber Crime is that group of activities made by the people by creating disturbance in network, stealing others important and private data, documents, hack bank details and accounts and transferring money to their own. Cyber Crime, especially through the Internet, has grown in importance as the computer has become central to commerce, entertainment, and government. Cyber crime, also called computer crime, the use of a computer as an instrument to further illegal ends, such as committing fraud, Trafficking in child pornography and intellectual property, stealing identities, or violating privacy. The cyber crime and they its impacts over the society in the form of economical disrupt, psychological disorder, threat to National defense etc. Restriction of cyber crimes is dependent on proper analysis of their behavior and understanding of their impacts over various levels of society. Now a day’s Cyber crime is increasing day by day. People have been greatly suffering for it. It is not only creates human suffering but also put effect on it. So Cyber Crime is one of the major crimes done by computer expert.  This paper gives the basic concept of cyber crime.
Estimation of the Global Solar Radiation in Anyigba Kogi State Using Hargreaver And Samani
Authors: Ayodele Abdullateef , Ohiani O. Alexander  , Adeyemi  O. John  , Papa M.A
Published: August 2022

ABSTRACT: This work estimates the global solar radiation in Anyigba with latitude 7.498 using Hargreaves and Samani model. The average monthly global radiation for Anyigba was found to be 32 MJ/m2 /day with a MBE of 15.6333 MJ/m2 /day and RMSE OF 5.985 MJ/m2 /day.
SKELETON-BASED ACTION RECOGNITION USING FEATURE FUSION FOR SPATIAL-TEMPORAL GRAPH CONVOLUTIONAL NETWORKS
Authors: Pham Dinh Tan
Published: August 2022

Human action recognition (HAR) has been used in a variety of applications such as gaming, healthcare, surveillance, and robotics. Research on utilizing data such as color, depth, and skeletal data has been extensively conducted to achieve high-performance HAR. Compared with color and depth data, skeletal data are more compact, therefore, they are more efficient for computation and storage. Moreover, skeletal data are invariant to clothing textures, background, and lighting conditions. With the booming of deep learning, HAR has received a lot of attention. Spatial-Temporal Graph Convolution Networks (ST-GCN) have proved to be state-of-the-art architecture for HAR using skeleton data. However, this does not hold when working with challenging datasets that contain incomplete and noisy skeletal data. In this paper, a new method is proposed for HAR by adding a Feature Fusion module and applying hyperparameter optimization. The performance of the proposed method is evaluated on the challenging dataset CMDFALL and the newly-built MICA-Action3D dataset. Experimental results show that the proposed method significantly improves the performance of ST-GCN on these challenging datasets.
Determination of radio wave propagation conditions in the atmosphere of Hanoi using the meteorological data
Authors: Pham Chi Cong
Published: August 2022

This article uses the data of radio occultation and the radiosonde data to determine radio refractive index and wave propagation conditions in the atmosphere of the Hanoi area. The content of this article uses the data of radio occultation in 2014-2016 and the radiosonde data in 2016-2018, showing that the radio refractive index tends to decrease with altitude, the maximum average value of radio refractivity is 370 N-units, the largest radio refractivity difference between years is not more than 11 N-units, at high altitudes the radio refractivity value is close to the value at standard model of the ITU-R while at a small altitude the difference between the model value and the observed value is up to 60 N-units, the vertical gradient of refractivity and the effective earth radius coefficient is independent with altitude. Based on radio refractivity, it is possible to determine tropospheric delay, which is input data for problems such as satellite positioning, altimetry satellite and under-the-horizon radar.
SYNTHESIS AND APPLICATION OF Cu-Fe HYDROTALCITE IN ALDOL REACTION
Authors: Nguyen Bich Ngoc
Published: August 2022

The heterogeneous recyclable catalyst, Cu-Fe hydrotalcite, was synthesized by coprecipitation, activated at 200oC and then successfully applied in Aldol reaction. The Aldol products were obtained in moderate yield under mild conditions, simple and environmentally benign process, with the recovery of hydrotalcite catalyst up to 99%. This procedure also exhibited efficiency in the total synthesis of Abhexone, a flavor with high demand in the food and cosmetic industry.
EFFECT OF SHAPE OF DOUBLE-CONE LINER ON PENETRATION DEPTH OF SHAPED CHARGE WITHOUT WAVE SHAPER
Authors: Bui Xuan Son
Published: August 2022

The paper presents the solution to increase the penetration for shaped charge, which has not a wave shaper, using the double cone liners while ensuring the conservation of liner’s mass compared with the traditional single cone liners. The calculation results of penetration for 44 mm small-caliber shaped charge have determined the position to change the angle of the double cone liner, at whichs the penetration depth of shaped charge increases by more than 16% compared with the penetration of the original single cone liner.
A VOLTAGE MODE CONTROL FOR SINGLE-PHASE INVERTERS IN PARALLEL OPERATION
Authors: Vu Hoang Phuong
Published: August 2022

The active and reactive power, P and Q, are important variables when dividing the load for parallel connected inverters using a droop controller. P and Q are calculated based on the transformer output voltage value and the load current. However, when it comes to sharing the nonlinear load power, low pass filters with very low cut-off frequency are used to eliminate harmonics of the load current for increasing accuracy when calculating P and Q. These filters slow down the dynamics of the system, reduce the reliability and cause control errors. This paper uses the DSOGI algorithm to replace the low pass filter, increasing the dynamics and stability of the system. The voltage mode control with a simple observer (DOB) can ensure that the quality of the inverters output voltage and current follows an IEEE standard. The algorithms were tested through simulation on Plecs, with system consists of 2 one phase inverters working in parallel.
SYNTHESIS OF FEEDBACK LINEARIZATION CONTROLLER WITH PARAMETERS OPTIMIZATION BASED ON BAT ALGORITHM FOR A MAGNETIC LEVITATION SYSTEM
Authors: Nguyen Xuan Chiem
Published: August 2022

In this paper, the method design controller based on the feedback linearization control (FLC) method with optimal parameter for time response thanks to BAT algorithm for magnetic levitation system (MLS). Feedback linearization controller based on equivalent transformations brings a nonlinear system into linear form, then uses the poles-placement method to find parameters for the linear tracking controller. The selected pole does not optimize the controller parameters when the system needs to satisfy a rapid response condition. Therefore, the authors use the BAT algorithm to find linear tracking controller parameters based on ITAE cost function. The controller with optimized parameters is verified through simulation and experiment results. The proposed controller efficiency is compared with the feedback linearization controller through the simulation results.
CONSTRUCTING DIGITAL SIGNATURE ALGORITHMS BASED ON NEW KEY SCHEMES
Authors: Nguyen Duc Thuy
Published: August 2022

The paper proposes a method of constructing digital signature algorithms based on the new key schemes. The new key schemes are difficult problems that currently have no solution. That algorithm construction method with a new key scheme is to improve the security of digital signature algorithms. The new method is showed through the construction of two specific digital signature algorithms and the generation of highly secure signature algorithms that are constructed by this method is completely possible.
PENGARUH PAJAK DAERAH, RETRIBUSI DAERAH DAN DANA ALOKASI KHUSUS TERHADAP PERTUMBUHAN EKONOMI KABUPATEN/KOTA DI JAWA TENGAH PERIODE 2015-2019
Authors: Rahman Kristanti , Yuliani Zubaedah Asih
Published: August 2022

This study was conducted with the aim of knowing and analyzing the effect of local taxes, regional retribution and special allocation funds on economic growth (a case study in districts/cities in Central Java). The sample of this study was determined using purposive sampling method. The type of data used was secondary data. In which the total samples selected in this study were 10 districts/cities. The data analysis method used is multiple linear regression analysis. The results of this study indicate that regional taxes and special allocation funds partially have no effect on economic growth, regional retribution has an effect on economics growths, and the influence of local taxes, regional retribution, special allocation funds have no effect on economic growth simultaneously. Further research is suggested to be able to expand the research sample, add variables, and extend the research period.
PENGETAHUAN ORANG TUA TERHADAP PERTUMBUHAN DAN PERKEMBANGAN BALITA MELALUI PENGGUNAAN BUKU KESEHATAN IBU DAN ANAK ( KIA )
Authors: Indria Gita Ayu
Published: August 2022

Toddler Period is an important stage in the growth and development of toddlers which is often called the golden age. In that period there are changes in physical growth and changes in cognitive development which are fundamental to the later stages of growth and development. This study aims to find out that parents' knowledge about the stages of growth and development can affect the growth and development process of toddlers in Kuripan Kidul Village, Kesugihan District, Cilacap Regency. This research is in the form of analytical research with a Cross Sectional Study. The sample used parents of toddlers, they are 40 respondents obtained by cluster random sampling. The results of this study show that there are differences in parents with sufficient knowledge of growth and development of toddlers, so the growth and development of toddlers will be in accordance with the stages of growth and development that are in the mother and child health Book. The results of the chi-square statistical test obtained 12,477 with a p-value of 0.001 and 100 persen ownership of the mother and child health Book. In parents who have knowledge of the growth and development of toddlers, there are no deviations in the growth and development of toddlers.
Therapeutic effects of cupping therapy in frozen shoulder: a review article
Authors: SHARMA RITA
Published: August 2022

ABSTRACT  
Frozen shoulder is a chronic aseptic inflammation caused by injury and degeneration of shoulder capsule and periarthritic soft tissue (including ligaments, muscles, tendons, synovial sacs, etc.). Cupping is gaining popularity in physical medicine due to its ease of use, lack of side effects, and pain relief. This study looked at the efficacy of cupping therapy for treating shoulder pain. However, because very little literature on the efficacy of cupping therapy in the frozen shoulder is available, further research is needed in this field.
Keywords: Cupping therapy, frozen shoulder, adhesive capsulitis, wet cupping therapy, dry cupping.
A review on the classification, preparation of nutraceuticals and their application
Authors: Farakh Munir  , Urvah Asif
Published: August 2022

Nutritional health products are a powerful tool for maintaining and improving human health. They can fight against acute and chronic diseases caused by nutrition deficiency that promote quality effectiveness of human life. Nutritional therapeutic properties are needed to improve human health but due to their poor bioavailability and depending on their chemical instability to pH, oxygen, temperature and absorption of food ingredients, and also their low intake and low gastrointestinal absorption, the nutritional health benefits still lag behind their potential. Some of these limitations can be resolved by using micron and nanocapsulation technologies that can provide new delivery systems to many food industry, enriching foods and beverages with nutraceuticals. Micron and nanoencapsules of nutritional products provide large variety of advantages related to their stability like thermal, pH, in vitro performance, improved bioavailability and biological activity. Nanocarriers like liposomes, Nanoemulsion, lipids and polymer nanoparticles, micelles and cyclodextrins complex used for the administration of nutritional products.
Nanoemulsion for skin drug delivery
Authors: Shams-ul-Hassan  , Muhammad Imran Khan  , Mubashra Gul  , Badarqa Tul Ayesha  , Maria Gul
Published: August 2022

The use of nanoemulsion in augmenting dermal and transdermal effectiveness of drugs has now well established. The development of nanoemulsion based semisolid dosage forms is an active area of present research. However, thickening or liquid-to-semisolid conversion of the nanoemulsions provides opportunities to the formulation scientist to explore novel means of solving instability issues during transformation. Extending knowledge about the explicit role of nature/magnitude of zeta potential, types of emulsifiers and selection of appropriate semisolid bases could place these versatile carriers from laboratory to industrial scale. Nanoemulsions are termed as biphasic (O/W or W/O) or multiple nanoemulsions (W/O/W). Oil phase components include fatty acids (e.g., oleic acid), esters of fatty acids and alcohols (e.g., isopropyl myristate, isopropyl palmitate, ethyl oleate), medium chain triglycerides, triacetin, terpenes (e.g., limonene, menthol, cineole) and other penetration enhancers. Till date several approaches have been employed to develop nanoemulsions (size range 20–200 nm) which are High-energy emulsification and Low-energy emulsification. NanoemulsionS are found effective to treat psoriasis, dermatitis and cancer.
Development and in-vitro characterization of tiropramide tablets having immediate- and extended release layers
Authors: Riaz Muhammad , Ali Liaqat , Javed Saba , Hussain Syed Aatif , Shah Hassan Haider , Anwer Khaleeq
Published: August 2022

Purpose: The objective of this study was to explore the feasibility of developing of Tiropramide, bilayer tabletusing an immediate- and extended-release formulation. Method: After rheological performance of drug-excipientsmixture, Tiropramide HCl bilayer tablets were prepared by wet granulation method. FTIR analysis was performed toelucidate the compatibility behavior of drug and excipients. Effect of these varying concentrations of EthylCellulose (EC) and Hydroxy Propyl Methyl Cellulose (HPMC) were observed on the sustained release pattern of thematrices. Dissolution was performed by using 0.1N HCl and phosphate buffer pH 7.2 as medium at 37.0 ±0.5 ºC,while the stirring speed was set at 50RPM. The bilayer tablets were stored under conditions 40±2oC temperature and 75±5% humidity for stability testing. Results: It was observed that as the quantity of polymers (HPMC or EC)increases the sustained release effect also increases. It was obvious from these models that drug release form bilayer tablets followed the zero order model and Higuchi square root model and the drug release mechanism was diffusion and erosion. The polymers-drug combination was compatible in bilayer tablets before and during stability testing. Conclusion: Bilayer tablet of Tiropramide can be developed successfully in which one layer provides immediate release while the other prolongs the drug release.
A review on smart bioresponsive drug delivery systems
Authors: Haleem Kainat , Khan Muhammad Arslan
Published: August 2022

During the past several decades, many sensing mechanisms have emerged, which provide new control strategies for designing closed-loop drug delivery systems. For such systems, numerous bioresponsive materials are utilized to construct functional modules for the desired devices. The typical closed-loop drug delivery systems recently reported in this review. The stimuli-responsive polymers serve to provide a snapshot of the utility and complexity of polymers that can sense, process, and respond to stimuli in modulating the release of a drug. Stimuli-responsive drug delivery vehicles come in the form of polymersomes, liposomes, micelles and dendrimers. Therapeutics is designed to be controlled released from drug carriers through the structural transformations such as shrinking, swelling, and dissociation or unique responsive cleavage route.
Preparation of mucoahesive tablets of famotidine by wet granulation method and its in-vitro testing
Authors: Alvi Zainab , Sharmeen Hira , Ayub Alina , Shahid Attia , Dildar Hafiza Nida , Imtiaz Mahnoor , Ejaz Iqra
Published: August 2022

Objective: Famotidine is a histamin H2-receptor antagonist.The aim and objective of the present work is toformulate and evaluate mucoadhesive tablets of famotidine. It is also foused on the selection of mucoadhesivepolymer & its activity in various combinations & ratios. The poor bioavialability & shorter half-life suffice thedevelopment of controlled release mucoadhesive formulation. Method: Mucoadhesive tablets each containing 20mg of famotidine were prepared by conventional wet granulation method employing as mucoadhesive materials. A batch of 50 tablets was prepared, in each case a blend of 1 gm of famotidine with different polymers addition indifferent strengths with required 40mg lactose as diluent achieved after titration which were then grannulated along with a solvent blend if water and ethyl alcohol. Results: The flow properties of all five batches were in between fair and passable. Hardness of tablets ranged from 6.9-8.2 kg/cm2 and the percentage friability was between 0.25-0.79 %. The drug content uniformity in the mucoadhesive tablets was 96.49-104.81%. The surface pH study was within the range from 6.7-7.4. From all formulations, over 20% of the famotidine was release within first hour of dissolution study. In the present study the formulation FT04 (tragacanth & HPMC ) has shown cumulative percent drug release of about 80.762% in 12 h. Conclusion: From the results we concluded that formulation containing famotidine with HPMC & tragacanth has given better drug release property than the other four formulations & the wash-off test has shown that this formulation (FT04) has better mucoadhesive property.
Drugs prescribed and adverse drug reaction monitoring in skin diseases
Authors: Ashraf Maham , Ali Huma Mahmood , Niaz Saba , Batool Moater , Rehman Fauzia , Nabi Ifra
Published: August 2022

Background: Skin diseases are more common due to bacteria and fungi, mostly antibiotics, antifungal, NSAIDs, corticosteroids, antipsoriatics and antiacne agents are prescribed. 10% of hospital admissions are due to these ADRsthat include anaphylactic shock, hypersensitivity reactions. Monitoring of ADRs associated with the use of these drugs can be monitored by various ways including spontaneous reporting, yellow card scheme, direct patient reporting, and case control and cohort studies. Method: It is a retrospective study conducted by reviewing researcharticles and journals like Journal American Medical Association, JAMA, American Society of Health System Pharmacists, MedCare etc. relating to skin diseases and ADR monitoring relating to use of drugs for treatment from1969 to 2016. Conclusion: Most prevalent skin diseases are acne, microbial infections, psoriasis, hypersensitivityreactions, fungal infections and drug used for their treatment results in various adverse drug reactions which should be monitored during the therapy. These ADRs may be associated with minor to life threatening conditions.
Evaluation of in vitro pharmacological activities of Diospyros malabarica kostel fruit
Authors: Sahar Javed  , Sabi Rehman  , Muzamil Zaman Khan  , Anwar Khalid  , Rida Qaseem  , Muhammad Humayun
Published: August 2022

Objective: To explore the in vitro pharmacological activities of fruit of Diospyros malabarica. Method: 70% ethanolic extracts of Diospyros malabarica was screened against ten pathogenic bacteria, five strains of gram +ve, five strains of gram –ve bacteria and fungi by using disc diffusion method. Moreover, to study the toxicity of this fruit, we conducted a saltwater shrimp lethality bioassay based on the ability to kill laboratory cultured brine shrimps (Artemiasalina). Results: Fruits extracts were found to exhibit antimicrobial activity against bacterial pathogens with the zone of inhibition ranges between 13mm to 19mm. Fruit Extracts was also tested for its antifungal activity against fungal strains exhibiting zone of inhibition ranges from 14 mm to 19 mm. The fruit extract of Diospyros malabarica shows significant lethality towards brine shrimps at LD50 value of 93.55 ppm. Conclusion: Plant extracts is potentially effective in suppressing microbial and fungal growth. As fruit extracts has significant LD50 value thus it can be further used for cancer cell line studies.
Prescription medication-induced psychosis: A high alert for drug experts
Authors: Najla Taslim  , Dustin Edge
Published: August 2022

Psychosis is a complex mental illness of behavioral, psychological, and emotional disturbances. Secondary psychosis can be elicited by prescription medications and literature is replete with examples of such drugs. Objectives: The goal of this article is to gather information from multiple published sources to highlight the culprit prescription medications that are linked with psychotic episodes and compose the findings into a simplified, standalone publication for readers to conveniently become aware of this phenomenon. It is also intended to reiterate the critical role and significance of the pharmacist as a vital player in a health care team. Methods: The scientific literature was searched on the PubMed database using the key search phrase “psychosis, medicines or drug or prescription.” The search was limited to the time period from 1960-2019 to ensure the inclusion of the vast majority of previously reported cases of currently available medicines and their related psychoses. Conclusion: Commonly prescribed medications can cause serious, albeit preventable, psychiatric issues. Pharmacists as vital players in patient care can avert the untoward psychotic episode by taking timely steps in notifying the prescribers or counseling the patient on measures to avoid serious and fatal psychotic issues.
A mini review: Cancer, types and its treatment alongwith its complications
Authors: Rabia Shakeel  , Ayesha Liaqat  , Huma Khalid
Published: August 2022

People differ from one another in many ways, including how our bodies work. How our bodies differ is still being studied; but some key differences are already known. Cancer can cause symptoms like pain and fatigue. Cancer treatment is used to remove or destroy cancer cells either by chemotherapy, surgery radiation but can also cause side effects. Side effects are unhealthy or unpleasant physical or emotional reactions to treatment. Side effects can also include pain or fatigue as well as many other symptoms. Not every patient with cancer gets symptoms. It depends on many factors. Such factors include the type and stage of cancer, and the type, length, and amount of treatment. In any case, relief from symptoms is often possible.
Formulation and evaluation of buccal bioadhesive tablets using glimepiride as a model drug
Authors: Syeda Sualyha Noor  , Muhammad Akram Choohan
Published: August 2022

Objectives: The present investigation is concerned with formulation and evaluation of bioadhesive buccal tabletscontaining antidiabetic drug, Glimepiride to circumvent the first pass effect and to improve its bioavailability because bioadhesion has shown renewed interest for prolonging the residence time of bioadhesive dosage forms through various mucosal routes in drug delivery applications. Bioadhesive-based topical and local systems have shown enhanced bioavailability. Bioadhesive drug delivery gives rapid absorption and good bioavailability due to itsconsiderable surface area and high blood flow. Drug delivery across the mucosa bypasses the first-pass hepaticmetabolism and avoiding the degradation of gastrointestinal enzymes and with reduction in dosing frequency and dose related side effects. Methods: The tablets were prepared by direct compression method. Six formulations weredeveloped with varying concentrations of polymers like sodium alginate, PVP and magnesium stearate. The tabletswere tested for weight variation, hardness, surface pH, drug content uniformity, percentage swelling index,bioadhesive strength, ex-vivo residence time in-vitro drug dissolution study, in-vitro drug release kinetic study, exvivo permeation study and Stability study. Results: FTIR studies showed no evidence on interactions between drug, polymers, and excipients. The surface pH, bioadhesive strength was found to be 6.22, 16g and, respectively. The formulation containing 4 mg of Glimepiride exhibited 6 h sustained drug release i.e. 93.98±0.8% with desiredtherapeutic concentration. The drug permeation from the formulation was slow and steady and 3.56 mg of Glimepiride could permeate through sheep buccal membrane with a flux of 0.27 mg hr-1 cm-2. The in-vitro release kinetics studies reveal that the formulation fits well with zero order kinetics. Conclusion: Hence, it was concluded that the formulation was suitable for all the evaluation parameters and can be permeated through human buccal mucosa.
Case study: A qualitative study aimed at comparing standard therapy in a breast cancer patient to the spiritual healing and psychological support, in improving patient’s compliance
Authors: Ali Hassan  , Hafiz Abdul Majeed  , Azizullah Kakar
Published: August 2022

Background: Breast tumor is the most well-known type of cancerous growth in ladies of Pakistan. The effect of theunderlying diagnosis, treatment conventions, chemotherapeutic agents in contrast with culture, social and psychological parts of the ailment is not settled. Method: This subjective review analyzed and contrasted thestandard treatment conventions and the Spiritual Healing including psychological support utilized by patient withbreast cancer in connection to its effect on the enhanced quality of her life and her enhanced wellbeing status. MrsFouzia Mohsin a patient with bosom malignancy persistent, mother of 6 youngsters having an age of 53 years and 5months from Faisalabad experiencing chemotherapy from Shifa International Hospital Islamabad and also SpiritualHealing and mental support was met. Information were dissected utilizing topical examination. The patient'sunderstanding of bosom disease concentrated on the conviction of suitability of medication treatment picked by herphysician and in addition the positive mental impact of Spiritual recuperating alongside the scope of feelings felt allthrough her ailment. Results: The significance of spiritual healing and mental support of the family along withbreast cancer tackling techniques i.e chemotherapy, radiotherapy and mastectomy is far excessively helpful andsteady in method for upgrading consistence to treatment and accordingly enhanced personal satisfaction. This is the principal study to look into the case of lady experiencing breast cancer on the experiencing chemotherapy andSpiritual Healing. This article gives illumination of the voiced encounters of a woman with breast tumor. The information not just highlights the part of standard chemotherapy and radiotherapy as fundamental adaptingmethodologies additionally underlines the adapting of issues like disengagement, hostility, and outrage as regularreactions to chemotherapy through Spiritual Healing and Psychological support of the family. Conclusion: One of akind elements are bosom malignancy patient's have to look for Spiritual Healing and Support of family for hersickness to remain spurred and increment in her consistence. These social elements require advance examination and research.