bluuebunny/crossref_metadata_2025 huggingface dataset:
Efectividad del Sellado Dentinario Inmediato como Método de Prevención ante la Sensibilidad Postoperatoria en Restauraciones Indirectas. Revisión Bibliográfica
Authors: Bucheli Naranjo Diego David , Armas Vega Ana , Vallejo Izquierdo Luis Alberto
Published: October 2023

Objetivo: Determinar la eficacia que ofrece el sellado dentinario inmediato como método de prevención ante la sensibilidad post operatoria en restauraciones indirectas mediante una revisión literaria en pubmed y google académico, entre los años 2019 y 2023. Metodología: Se planteó una investigación mediante una revisión descriptiva, donde se recopilaron artículos científicos publicados en diferentes sociedades de investigación dedicadas a la salud. Se comenzó con la búsqueda de artículos en la plataforma virtual Pubmed y posteriormente en bibliotecas virtuales como google académico, se efectuó la búsqueda utilizando palabras claves de búsqueda como “sellado destinario inmediato” y “sensibilidad postoperatoria” y sus equivalentes en inglés.  En la búsqueda inicial produjo un total de 508 artículos de interés tanto en idioma inglés, portugués y español, distribuidos 475 google académico y 33 en pubmed. Luego se procedió a descartar 495 artículos que no cumplían con la relación entre la eficacia que ofrece el sellado dentinario inmediato como método de prevención ante la sensibilidad post operatoria en restauraciones indirectas, e artículos relacionados o con mención a sensibilidad en restauraciones indirectas, se excluyeron aquellos que no cubrieron los elementos de búsqueda, duplicados, así como tesis, monografías y artículos que no tenía un acceso completo y libre. Se seleccionaron 13 artículos que cumplían con los criterios de inclusión establecidos, los cuales fueron publicados entre los años 2019 y 2023 y mantenían su enfoque en el tema de interés. Conclusión: La literatura revisada muestra que la ejecución del protocolo SDI ofrece prevenir la sensibilidad postoperatoria en restauraciones indirectas.
Plan Estratégico de Educación Rural en Colombia y desarrollo económico territorial: Una mirada a las estrategias dirigidas a los docentes
Authors: Ortega Rolando
Published: October 2023

Plan Estratégico de Educación Rural en Colombia y desarrollo económico territorial: Una mirada a las estrategias dirigidas a los docentes
Metodología de investigación doctoral vinculada al diseño curricular de una propuesta de formación en competencias digitales para docentes colombianos
Authors: Ortega Rolando
Published: October 2023

Metodología de investigación doctoral vinculada al diseño curricular de una propuesta de formación en competencias digitales para docentes colombianos
Adesão ao tratamento farmacológico em pacientes com doenças cardiovasculares no sul do Brasil
Authors: Ortega Rolando
Published: October 2023

Adesão ao tratamento farmacológico em pacientes com doenças cardiovasculares no sul do Brasil
O Povo Indígena Palikur e Sua Identidade Étnica na Prática Pedagógica Dos Professores na Amazônia Amapaense
Authors: Ortega Rolando
Published: October 2023

O Povo Indígena Palikur e Sua Identidade Étnica na Prática Pedagógica Dos Professores na Amazônia Amapaense
Biomarcadores salivares como ferramenta de triagem diagnóstica para Amelogênese Imperfeita: Resultado de estudos preliminares
Authors: Ortega Rolando
Published: October 2023

Biomarcadores salivares como ferramenta de triagem diagnóstica para Amelogênese Imperfeita: Resultado de estudos preliminares
Representación Iconográfica e Iconológica de la Chakana y los 4 Raymis en el Ecuador para Su Difusión y Preservación
Authors: Ortega Rolando
Published: October 2023

Representación Iconográfica e Iconológica de la Chakana y los 4 Raymis en el Ecuador para Su Difusión y Preservación
Observatorio virtual de la industria de software campechana.
Authors: Ortega Rolando
Published: October 2023

Observatorio virtual de la industria de software campechana.
Repensar el dispositivo jurídico de los Derechos Humanos desde la biopolítica y los conceptos de Zoé y Bíos
Authors: Ortega Rolando
Published: October 2023

Repensar el dispositivo jurídico de los Derechos Humanos desde la biopolítica y los conceptos de Zoé y Bíos
Competencias de los docentes STEM en secundaria: percepciones de los directivos docentes
Authors: Rincón Sánchez Astrith Eugenia
Published: October 2023

Competencias de los docentes STEM en secundaria: percepciones de los directivos docentes
Materiales comerciales de maíz, para los procesos de producción y conservación de forraje en forma de ensilaje
Authors: Ortega Rolando
Published: October 2023

Materiales comerciales de maíz, para los procesos de producción y conservación de forraje en forma de ensilaje
Comunicación Interpersonal y la Satisfacción Laboral de los trabajadores de la Unidad de Gestión Educativa Local Tumbes 2022
Authors: Campos Supo Cristofers Damián
Published: October 2023

Comunicación Interpersonal y la Satisfacción Laboral de los trabajadores de la Unidad de Gestión Educativa Local Tumbes 2022
GERMANY NEEDS SKILLED INDIAN MIGRANT LABOUR
Authors: Maurya Rohit , Donthula Dr. Vinai Kumar
Published: October 2023

Germany is the fourth largest economy in the world, after the USA, China, and Japan, but Germany still needs huge amount of skilled labour especially skilled Indian migrant labour. This Study provides a descriptive analysis of the need for skilled Indian migrant labour in Germany, and according to BAMF (the federal office for migration and refugees), most highly educated Indians are shifting to Germany every year, not only for higher education and employment but also for business purposes, and Germany also needs them, for whom the Federal Republic of Germany tries to make an attractive immigration policy as well as act for skilled workers. But question is arising: why does Germany need skilled Indian migrant labour? Why does Germany want the most a greater number of Indian migrants except Chinese migrants? What does Germany do to attract Indian Migrants? What is the policy for them if they want to work there and try to integrate into German society? This Study was carried out using the labour migration and pull and push migration theory as a method, which includes newspapers, magazines, books, documents from government agencies, related articles, annual reports etc.
A STUDY ON WORK SAFETY OF HEALTHCARE EMPLOYEES
Authors: Bhatia Vishesh , Dhaliwal Dr. Amandeep
Published: October 2023

The ancient pandemics like situations partake brought out trendy open the shortcomings of administration to guard the health and safety of their employees especially in the healthcare sectors. Because of this many of the healthcare organizations nowadays have started giving a lot of attention to work safety of their employees. The health and safety management norms have been set up for the same to avoid as such major disasters. In the healthcare industry, a culture of safety and the performance of safety protocol is followed keeping in mind the employee or workers safety. But even then due to the “people” element, unsafe behaviours leading to accidents. Therefore this research intends to study the work safety of healthcare employees in healthcare sector. An empirical study was undertaken where the employees of a multispecialty hospital were asked to respond to questionnaire to collect their perception towards the employees work safety and all the procedures that are being performed regarding work safety of any employee in the organisation. The results revealed that though organisations are doing a lot for employee safety but still some major concerns remain. This research would be very helpful in promoting the work safety culture.
New records for the wild bee fauna (Hymenoptera, Anthophila) of Serbia
Authors: Mudri-Stojnić Sonja , Andrić Andrijana , Józan Zsolt , Likov Laura , Tot Tamara , Grković Ana , Vujić Ante
Published: October 2023

Numerous scientific projects have been initiated with the aim of tackling the decline in insect pollinators, a crucial group for the functioning of terrestrial ecosystems. One of the first steps is to address information gaps on species spatial distribution, diversity, and abundance that prevent effective conservation actions in Europe. Given that Serbia belongs to the understudied areas, efforts are being made to improve knowledge of its bee diversity and abundance. The present study includes the monitoring of bees at 54 sites, surveyed three times during 2022. The conducted protocol combined two methods, transect walks and pan traps, resulting in the discovery of 312 bee species. The main results present the records of 25 species, not previously mentioned in Serbia, while another important finding is the confirmation of the presence of 26 species, without any available records from the 21st century. Moreover, 79 here examined species were known only from literature-based data. Six of the recorded species are considered threatened and 67 (10 newly recorded) have been assessed as Data Deficient in the European Red List of Bees. Therefore, the present study not only contributes to an update and confirms the list of bee species in Serbia, that now counts 731 species, but also provides additional information about European distribution, required for new assessment at the European level. In addition, the results indicate that the combination of complementary sampling methods is an effective way to assess bee diversity and abundance.
The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studies
Authors: Gevrenova Reneta , Balabanova Vessela , Zheleva-Dimitrova Dimitrina , Momekov Georgi
Published: October 2023

Several species of the genus Tanacetum L. (Asteraceae) spread in the Southestern Europe are traditionally used as medicinal and aromatic plants, including T. vulgare, T. parthenium, T. macrophyllum, T. balsamita, T. poteriifolium. The review is focused on the phytochemical and pharmacological studies of these taxa. Major chemical constituents are acylquinic acids, sesquiterpenes, sesquiterpene lactones, methoxylated flavonoids. An in-depth depiction of more than 100 secondary metabolites was achieved in Tanacetum species by liquid chromatography-high resolution mass spectrometry. The ethnopharmacological studies indicate that species possess antioxidant, enzyme inhibitory and cytotoxic activity along with antimicrobial and antiviral effects. Reports revealed anti-inflamatory and neuromodulatory activity involved in the pharmacological approach in counteracting migraine attacks. Multivariate data analysis allowed the identification of the most discriminant metabolites and bioactivities in the herbal drugs. This review emphasizes T. vulgare, T. macrophyllum, T. balsamita and T. parthenium as potential raw material for health-promoting application in pharmaceutical area.
Une autre histoire (algérienne) de la France est possible
Authors: Sidi Moussa Nedjib
Published: October 2023

De la guerre d’indépendance à l’immigration postcoloniale, la colonisation de l’Algérie demeure centrale dans les débats de l’ancienne métropole. Se confronter à cette question peut aider à comprendre la France contemporaine, par-delà les peurs et les fantasmes.
L’innovation organisationnelle dans les organisations publiques : le cas du Parc olympique
Authors: Brunet Maude , Adam Mélanie , Brodeur Joëlle
Published: October 2023

Ce papier aborde l’innovation organisationnelle dans une organisation publique, vue comme le résultat d’un changement systémique complexe et social. La restructuration interne d’un secteur d’activités du Parc olympique est au cœur de cette analyse, avec la création d’une direction Bureau de projets. Une collecte de données incluant 6 entrevues semi-dirigées avec des acteurs stratégiques du Parc olympique, ainsi que l’analyse de documents internes, permet de mettre en lumière la démarche de transformation organisationnelle. Les résultats illustrent les leviers d’action déployés par cette organisation publique pour mener sa transformation. Une discussion élargit le sujet de l’innovation organisationnelle dans les organismes publics et souligne les principales contributions et limites de l’étude.
Le rôle de la débrouillardise et de l’innovation frugale dans le succès des jeunes femmes entrepreneures camerounaises
Authors: Sangué-Fotso Robert , Dida Ngouane Chaveline
Published: October 2023

Très souvent cachée derrière son homologue masculin, la femme entrepreneure est quelquefois obligée de se contenter d’une description masculine de sa position. Questionner le succès au féminin devient alors intéressant ; surtout lorsqu’on discute des comportements des entrepreneurs naissants. Pour atteindre notre objectif, nous mobilisons une approche qualitative basée sur des récits de vie de deux jeunes femmes entrepreneures, dans le but de comprendre le rôle que jouent la débrouillardise et l’innovation frugale dans le succès des jeunes femmes entrepreneures. Si les stéréotypes de genre affectent l’initiative féminine, la débrouillardise leur permet de démarrer, et l’innovation frugale de se réaliser et de rêver encore plus grand. Telles sont les principales conclusions de cette recherche.
Promoting peer learning in education: Exploring continuous action iterated dilemma and team leader rotation mechanism in peer-led instruction
Authors: Yin Xiangwen
Published: October 2023

This paper promotes teacher-guided peer learning in education with continuous action iterated dilemma (CAID) based on team leader rotation mechanism. In previous teaching activity models, the learning communication relationship between peers was described as static, but the static relationship will hinder the learning efficiency, which does not match the real world. In addition, in view of the independence of individual students, it is necessary to establish a dynamic model which considers the complex behavior of every student. In this paper, we first propose a team leader rotation mechanism that makes sure each student has the opportunity to become a team leader, which enhances students' sense of participation and improves classroom efficiency. Next, we establish a multi-layer nonlinear student dynamic model based on continuous action iteration dilemma and involved complex and unknown nonlinear environmental factors to fit different environmental influences on different students. Also, in order to demonstrate the convergence of the proposed model, we devise the Lyapunov function as a means of mathematical proof. Through this analysis, we establish the stability of the proposed model and verify its independence from parameters, thereby enhancing its applicability in practical contexts. By incorporating the team leader rotation mechanism proposed in this paper, teachers will be able to ensure diverse student engagement to achieve information consistency, thereby ensuring the effectiveness of the classroom.
The Restoration and Refunctionalisation of Medieval Fortified Manor Houses by the Portuguese Dictatorial Regime (1926–1974)
Authors: Rodrigues dos Santos Joaquim
Published: October 2023

In the Modern Age, most fortified manor houses in Portugal fell into ruin, due to the lack of dignified living conditions, the obsolescence of defensive structures, and the decline decay of aristocratic families. However, between 1933 and 1974, many ruined fortified manor houses were restored by the Portuguese dictatorial regime. The nationalist dictatorship of Estado Novo used heritage as an ideological instrument of propaganda. This proposal aims to analyse the context of the ideological restoration of medieval fortified manor houses by the dictatorial regime, addressing symbolisms, restoration actions, and the contextualisation of fortified manor houses in Portugal by focusing on particular case studies.
Nuevos datos faunísticos e interacciones de moscas piojo (Diptera: Hippoboscidae) parasitando aves capturadas con redes japonesas en el Sistema Central (España)
Authors: González‍ Mikel A. , Hidalgo‍ Juan Carlos , Talabante‍ Carlos , Bernal Iván
Published: October 2023

Las moscas piojo (Diptera: Hippoboscidae) son ectoparásitos permanentes de aves y mamíferos. La abundancia y composición faunística de los hipobóscidos de España está relativamente poco estudiada, con 20 especies registradas hasta el momento. El objetivo de este estudio es aportar datos nuevos sobre estos ectoparásitos a partir de hospedadores aviares recogidos con redes japonesas en dos estaciones de anillamiento del Sistema Central en Madrid (España). Se identificaron cuatro especies generalistas de moscas piojo de la subfamilia Ornithomyinae, obtenidas de 13 hospedadores aviares (Orden: Passeriformes). Estas especies son, en orden de abundancia decreciente: Ornithomya fringillina (Curtis, 1936), Ornithophila metallica (Schiner, 1864), Ornithomya avicularia (Linnaeus, 1758) y Ornithoica turdi (Oliver in Latreille, 1811). El alcaudón común Lanius senator Linnaeus, 1758 fue la especie de ave más comúnmente parasitada por hipobóscidos. Se proporcionan nuevos datos faunísticos e interacciones aves-parásito para España.
Compuestos de yeso con adición de fibras textiles posconsumo de algodón
Authors: Castillo Rodríguez Anabel Patricia , García Navarro Justo
Published: October 2023

La sostenibilidad en la construcción es clave en la reducción del consumo de recursos como materiales y energía, es fundamental adoptar acciones eficientes en procesos de construcción como la reutilización de residuos. Por ello, el presente trabajo analiza la influencia de la incorporación de residuos textiles posconsumo de algodón en las propiedades físico-mecánicas de compuestos de yeso. Se realizó un trabajo experimental en donde se ensayaron probetas de yeso adicionadas con fibras posconsumo de algodón en diferentes formatos, y longitudes (20 y 35mm), adiciones de 0,5% y fibras de 35mm de longitud incrementaron la resistencia a flexión y compresión en un 5,9% y 11% respectivamente, y la absorción de agua por capilaridad descendió un 26% con el 1% de adición. Finalmente se observó que las fibras reducen el desprendimiento de fragmentos de yeso al momento de alcanzar la carga de rotura, mejorando la tenacidad de los compuestos.
A Boosted Evolutionary Neural Architecture Search for Timeseries Forecasting with Application to South African COVID-19 Cases
Authors: Akinola Solomon Oluwole , Qingguo Wang , Olukanmi Peter , Tshilidzi Marwala
Published: October 2023

In recent years, there has been an increase in studies on time-series forecasting for the future occurrence of disease incidents. Improvements in deep learning approaches offer techniques for modelling long-term temporal relationships. Nonetheless, this design practice is rigorously painstaking, prone to errors, and requires human expertise. The advent of feature enrichment with automatic architecture search typically optimises the discovery of new neural architectures applicable in domains such as time-series modelling. The main methodological contribution of this study is an approach for time-series forecasting using feature-enriched filters and an evolutionary neural architecture search with sequence-to-sequence gated recurrent units (GRU-Seq2Seq). This is applied to the prediction of daily cases of coronavirus disease in South Africa. The highly pathogenic coronavirus pandemic incident data was modelled with filters, optimised hyper-parameter search trials and an evolutional neural algorithm. The proposed model was benchmarked against ARIMA and SARIMA. The model predicted trends for 30, 60 and 90-day horizons and evaluated them for 7, 14 and 31 days. Simulation results demonstrate that observed daily case counts with added filters and evolutionary search optimisation for forecasting improve performance accuracy. Generally, the proposed bFilter+GRU-Seq2Seq with optimal search configuration outperformed ARIMA and SARIMA with lower error scores and higher performance metrics, with an R2 score of 7.48E-01 for a 30-day forecast horizon.
Smart Environments through the Internet of Things and Its Impact on University Education: A Systematic Review
Authors: Chamorro-Atalaya Omar , Morales-Romero Guillermo , Quispe-Andía Adrián , Caycho-Salas Beatriz , Ramos-Salazar Primitiva , Cáceres-Cayllahua Elvira , Arones Maritza , Auqui-Ramos Renan
Published: October 2023

At present, there is diverse scientific evidence of the contributions of smart environments (SE) that have positively impacted various urban problems. However, the concept of SE is very broad, so it is relevant to investigate how these technological trends have been integrated into the university educational environment. Therefore, the objective of this study is to explore and describe the state of the art on the impact of intelligent environments implemented through the Internet of Things (IoT) in university education. Therefore, a systematic review of the literature was developed. The research was developed with a mixed approach and descriptive scope. From this study, it was determined that the purpose of implementing SE in university education is focused on contributing to the teaching and learning process and managing and optimizing the use of resources provided by the educational environment. In addition, smart classrooms are the type of environments that have been implemented to a greater extent and whose results show a positive impact on indicators such as motivation, participation, interaction, satisfaction, and student attitude. With which it is concluded that universities should reflect on the implementation of institutional policies that lead to the progressive implementation of SE, seeking to transcend from being just simple learning classrooms to sustainable environments that contribute to student health and environmental conservation.
Quality of 3D Printed Objects Using Fused Deposition Modeling (FDM) Technology in Terms of Dimensional Accuracy
Authors: Alaa Aljazara  , Nadine Abu Tuhaimer  , Ahmed Alawwad  , Khalid Bani Hani  , Abdallah D. Qusef  , Najeh Rajeh Alsalhi  , Aras Al-Dawoodi
Published: October 2023

3D printers are known for providing parts with relatively good accuracy. However, the level of accuracy in the dimensions of printed objects may not matter if they do not have a mechanical purpose. When multiple 3D-printed parts are intended to be integrated with each other to create a larger system, even a fraction of a millimeter can have a significant impact on the entire system. This study aims to investigate the variation in dimension when a single print file is replicated using the same slicing settings. The findings are then analyzed using quality control tools and compared to the designed measurements. Fused deposition modeling (FDM) technology or fused filament fabrication (FFF) technology was chosen for this study due to its availability to the common user, its relatively low cost, and its increasing popularity in different applications and industries. The material used in this study is polylactic acid (PLA) which is a thermoplastic and the most widely used plastic filament in 3D printing. It has a low melting point, high strength, low thermal expansion, and is relatively cheap. The dimensional accuracy of FDM-produced parts was evaluated by comparing the dimensions of the fabricated specimens with their computer-aided design (CAD) models. Statistical analysis revealed that the mean dimensional deviations were within the specified tolerance limits for most of the tested parts. This suggests that FDM technology is reliable in terms of achieving dimensional accuracy.
Biological Control of Nematodes in Citrus Orchards
Authors: Abobatta Fouad , Swamy Chidanandamurthy Thippeswamy
Published: October 2023

There are various challenges facing citrus orchards, including abiotic and biotic threats. In citrus orchards, nematodes are one of the significant biotic stressors that cause severe threats on growth and fruiting of citrus trees. Managing nematodes in citrus orchards reduces tree decline, decreasing various hazards of chemical nemacides on environment and humanity. Using biological control enhances tree growth, improves productivity, and protects the environment. There are different methods to manage the nematode problem in different crops, including physical techniques, crop rotation, resistant varieties, in addition to biological control. Using multiple strategies to control nematodes is beneficial and safer through reducing the use of nematicides and utilizing environmentally friendly substances, which are safer for human health and protect the environment. Presently, there is more interest in using organic nematicides to control plant-parasitic nematodes because of their positive impacts on crop productivity, soil, and the environment.
Cyber Security Strategies
Authors: Partsvania Liza
Published: October 2023

In this chapter, the main concept of cyber security strategy and policy of several states in the field of cyber defense policy are discussed and analyzed. This factor allows the authors to make a comparative analysis of the cyber security strategies of such states and organizations as NATO, the European Union, the USA, Estonia, Lithuania, and Georgia. Particularly, there are analyzed appropriate documents in the field of cyber security and cyber defense taking into account the current realities in world politics.
EU's Cyber Security Strategy Before and During the War in Ukraine
Authors: Bitsadze Tamari
Published: October 2023

This chapter first examines the European Union's cyber security strategy and then analyzes the common principles of the member states in this regard. The authors discuss the European Union's role in the advancement of cyber security. In addition, the chapter reviews the EU Convention on Cybercrime. Most importantly, they discuss the impact of the most important and relevant issue, the Russia-Ukraine war, on the EU's cyber security strategy and investigate what changes and challenges the ongoing conflict in Ukraine has brought to the EU's cyber security strategy.
Driving Social and Environmental Impact
Authors: Mızrak Filiz
Published: October 2023

The pursuit of sustainability and corporate social responsibility has become critical for businesses as they strive to create positive social and environmental impacts while ensuring long-term profitability. This chapter investigates the significance and implementation strategies of sustainability and corporate social responsibility in driving positive social and environmental impacts for businesses. By analyzing the origins, key principles, and practical applications of these frameworks, the research explores the evolving societal expectations and regulatory landscape that demand responsible and sustainable business practices. It examines the benefits and challenges associated with adopting sustainability and CSR, drawing on case studies of successful organizations that have integrated these principles into their core strategies. The findings contribute to the existing knowledge on sustainability and CSR, offering insights for practitioners, policymakers, and researchers, and encouraging businesses to embrace these frameworks to create long-term value for society and the environment.
Public-Private Partnership as a Strategy for Infrastructure Development
Authors: Baporikar Neeta
Published: October 2023

Infrastructure development (ID) is a major force behind progress in developing nations and a crucial enabler of productivity and long-term economic growth. The crucial element that might raise a nation's socioeconomic standards is the development of its infrastructure. In general, emerging nations have been constrained in their ability to build their infrastructure, and due to the increasingly competitive global environment, governments are seeking inventive ways to develop infrastructure. Increasingly, public-private partnerships (PPP) are being used to take advantage of and benefits that both the public and private sectors can offer. Namibia is no exception and so the government aspires to use PPPs as a tool to reach the country's objectives of infrastructure development. Hence, adopting a qualitative approach, this chapter intends to investigate the role of PPPs in infrastructure development and examine the part that PPPs perform in infrastructure development strategy and also provides a PPP strategic framework that can be utilized to guide future projects.
Prior SARS-CoV-2 Infection Enhances Initial mRNA Vaccine Response with a Lower Impact on Long-Term Immunity
Authors: Silva-Moraes Vanessa , Souquette Aisha , Sautto Giuseppe A , Paciello Ida , Antonelli Giada , Andreano Emanuele , Rappuoli Rino , Teixeira-Carvalho Andréa , Ross Ted M
Published: October 2023

Spike-encoding mRNA vaccines in early 2021 effectively reduced SARS-CoV-2–associated morbidity and mortality. New booster regimens were introduced due to successive waves of distinct viral variants. Therefore, people now have a diverse immune memory resulting from multiple SARS-CoV-2 Ag exposures, from infection to following vaccination. This level of community-wide immunity can induce immunological protection from SARS-CoV-2; however, questions about the trajectory of the adaptive immune responses and long-term immunity with respect to priming and repeated Ag exposure remain poorly explored. In this study, we examined the trajectory of adaptive immune responses following three doses of monovalent Pfizer BNT162b2 mRNA vaccination in immunologically naive and SARS-CoV-2 preimmune individuals without the occurrence of breakthrough infection. The IgG, B cell, and T cell Spike-specific responses were assessed in human blood samples collected at six time points between a moment before vaccination and up to 6 mo after the third immunization. Overall, the impact of repeated Spike exposures had a lower improvement on T cell frequency and longevity compared with IgG responses. Natural infection shaped the responses following the initial vaccination by significantly increasing neutralizing Abs and specific CD4+ T cell subsets (circulating T follicular helper, effector memory, and Th1-producing cells), but it had a small benefit at long-term immunity. At the end of the three-dose vaccination regimen, both SARS-CoV-2–naive and preimmune individuals had similar immune memory quality and quantity. This study provides insights into the durability of mRNA vaccine-induced immunological memory and the effects of preimmunity on long-term responses.
First record of naturalization of Erechtites hieraciifolius (L.) Raf. ex DC. (Asteraceae) in Italy
Authors: Trotta Giacomo , Castello Miris , Petruzzellis Francesco , Pischedda Sara , Boscutti Francesco
Published: October 2023

The plant species Erechtites hieraciifolius (Asteraceae) is here reported for the first time in Italy as a naturalized neophyte in the Classical Karst. The species was observed in 2023 in post-fire forest areas burnt by wildfires in the summer 2022. The features of findings suggest for a naturalization of the species with putative invasive character. This novel occurrence highlights the need for additional research to better understand its colonization and expansion, suggesting the need of early eradication actions.
Neuronal conversion from glia to replenish the lost neurons
Authors: Liang Shiyu , Zhou Jing , Yu Xiaolin , Lu Shuai , Liu Ruitian
Published: October 2023

Neuronal injury, aging, and cerebrovascular and neurodegenerative diseases such as cerebral infarction, Alzheimer's disease, Parkinson's disease, frontotemporal dementia, amyotrophic lateral sclerosis, and Huntington's disease are characterized by significant neuronal loss. Unfortunately, the neurons of most mammals including humans do not possess the ability to self-regenerate. Replenishment of lost neurons becomes an appealing therapeutic strategy to reverse the disease phenotype. Transplantation of pluripotent neural stem cells can supplement the missing neurons in the brain, but it carries the risk of causing gene mutation, tumorigenesis, severe inflammation, and obstructive hydrocephalus induced by brain edema. Conversion of neural or non-neural lineage cells into functional neurons is a promising strategy for the diseases involving neuron loss, which may overcome the above-mentioned disadvantages of neural stem cell therapy. Thus far, many strategies to transform astrocytes, fibroblasts, microglia, Müller glia, NG2 cells, and other glial cells to mature and functional neurons, or for the conversion between neuronal subtypes have been developed through the regulation of transcription factors, polypyrimidine tract binding protein 1 (PTBP1), and small chemical molecules or are based on a combination of several factors and the location in the central nervous system. However, some recent papers did not obtain expected results, and discrepancies exist. Therefore, in this review, we discuss the history of neuronal transdifferentiation, summarize the strategies for neuronal replenishment and conversion from glia, especially astrocytes, and point out that biosafety, new strategies, and the accurate origin of the truly converted neurons in vivo should be focused upon in future studies. It also arises the attention of replenishing the lost neurons from glia by gene therapies such as up-regulation of some transcription factors or down-regulation of PTBP1 or drug interference therapies.
The bumpy road of purinergic inhibitors to clinical application in immune-mediated diseases
Authors: Wyss Matthias T. , Heuer Christine , Herwerth Marina
Published: October 2023

Purinergic signaling plays important roles throughout the body in the regulation of organ functions during and following the disruption of homeostasis. This is also reflected by the widespread expression of two families of purinergic receptors (P1 and P2) with numerous subtypes. In the last few decades, there has been increasing evidence that purinergic signaling plays an important role in the regulation of immune functions. Mainly, signals mediated by P2 receptors have been shown to contribute to immune system-mediated pathologies. Thus, interference with P2 receptors may be a promising strategy for the modulation of immune responses. Although only a few clinical studies have been conducted in isolated entities with limited success, preclinical work suggests that the use of P2 receptor inhibitors may bear some promise in various autoimmune diseases. Despite the association of P2 receptors with several disorders from this field, the use of P2 receptor antagonists in clinical therapy is still very scarce. In this narrative review, we briefly review the involvement of the purinergic system in immunological responses and clinical studies on the effect of purinergic inhibition on autoimmune processes. We then open the aperture a bit and show some preclinical studies demonstrating a potential effect of purinergic blockade on autoimmune events. Using suramin, a non-specific purinergic inhibitor, as an example, we further show that off-target effects could be responsible for observed effects in immunological settings, which may have interesting implications. Overall, we believe that it is worthwhile to further investigate this hitherto underexplored area.
Reviewers
Authors: Yilmaz Nadir
Published: October 2023

Reviewers
Evaluating agromorphological traits of Greek wheat landraces and exploring their potential for bread and pasta making based on seed physical properties
Authors: Protonotariou Styliani , Thanopoulos Ricos , Katsileros Anastasios , Bebeli Penelope , Mandala Ioanna
Published: October 2023

Physical and morphological characteristics of Greek wheat landrace and cultivar seeds were evaluated, aiming to assess their bread- and pasta-making quality. Furthermore, the plant agromorphological traits of wheat landraces and cultivars were measured and correlated with seed physical properties. Fifteen Triticum spp. accessions, out of which four cultivars (two Triticum aestivum and two T. durum), nine landraces (two T. durum, five T. aestivum, one T. dicoccum and one T. polonicum) and two T. durum of unknown status were studied. Seventeen morphological plant and seed traits were measured based on UPOV descriptors. Ear emergence was earlier in cultivars than in landraces. The plant weight of the landraces was, in some cases, almost twice the cultivars’. Seed firmness (62.96–194.85N) was positively correlated with thousand kernel weight and volume (0.840 and 0.791, P < 0.05, respectively). Based on the agromorphological traits, cluster analysis clearly separated the species and the cultivars from the landraces, and the unknown status accessions were grouped with the cultivars. Cluster analysis with all measured traits set the wheat accessions in the following distinct groups: (1) T. durum cultivars including the unknown status accessions, (2) T. aestivum cultivars, and (3) T. aestivum and T. durum landraces. T. polonicum and T. dicoccum each formed a separate group. Seed physical properties of the analyzed Greek landraces indicated their suitability for bread and/or pasta making.
Internal audit as an effective tool in Corporate Governance in Omani shipping companies (asyad)
Authors: Dr. Badriya Nasser Said Al Shammakhi  , Jumana Ali Abdullah Al Raisi  , Salema Harib Saif Al Maqrashi  , Saif Salim Harib Al Shuaaili  , Salim Hilal Salim Al Toubi
Published: October 2023

The report purpose is to evaluate how internal audits are handled in the shipping companies in the logistic transportation field. A majority of quality, independence, competence, and effectiveness of internal auditors have been examined and checked. Material out of both primary and secondary data sources were utilized in the research. Internal auditors and employees of Omani shipping enterprise were the area of focus. The demography inquiry and assessment of internal auditors were both detailed using correlation and frequencies analysis. The SPSS 29 version was utilized for the analysis of data. The Pearson correlation and significance improved a meaningful description. Correlation analysis findings revealed that internal audit effectiveness in Omani shipping companies was subpar, but also that internal audit quality, independence, and competence were all determined to be good. When internal auditors are competent and independent, as well as management is much more dedicated, quality of internal auditing within the enterprise will improve. The study is significant for investigators since it enhances knowledge of the variables that influence internal audit quality. Likewise, managers could use the study finding to address the actual issue impacting Omani shipping companies. Finally, future study might be done to evaluate how external auditors, for instance, evaluate the quality internal audits.
DRIFT spectroscopy and permutation importance algorithm in quantitative analysis of organic matter in soil model systems
Authors:   University of Novi Sad, Faculty of Sciences, Serbia, Jović Branislav D. , Panić Marko N. ,   University of Novi Sad, Biosense Institute, Serbia
Published: October 2023

In order to obtain useful MIR spectrochemical data of soil organic matter for the development of remote sensing methods, synthetically prepared soils with artificial precisely defined organic matter fractions, DRIFT spectroscopy and permutation importance algorithm were used in this paper. In terms of imitation of soil organic matter, sample model systems were prepared with precisely defined added values of added organic components. After MSC and SNV spectral treatments using PCA and LDA techniques and DRIFT spectra, the soil was classified according to the percentage of organic matter. Using the KDE+permutation importance algorithm, three significant MIR spectral regions were obtained for percentage grouping: 600-1000cm-1(skeletal vibrations of organic matter); 1750-2250cm-1 (Total reflectance+quartz overtones) and 3250-3950cm-1 (Hydroxyl groups). In terms of the potential for quantitative analysis, the calculated wavelength ranges match well with the classical spectrochemical theoretical basis of analytical methodologies. Also, extracted useful spectrochemical data can be potentially used in the development of new remote-satellite detection methods (ASTER satellite in SWIR and MIR range).
The influence of pyrocatechol added in pre-oscillatory period on the dynamics of the Bray-Liebhafsky reaction
Authors:   University of Belgrade, Faculty for Physical Chemistry, Serbia, Maksimović Jelena , Stevanović Kristina ,   University of Belgrade, Institute of Nuclear Sciences Vinča, Serbia, Simović-Pavlović Marina ,   University of Belgrade, Faculty of Mechanical Engineering, Serbia, Pagnacco Maja ,   University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Serbia
Published: October 2023

In the past two decades, chemical oscillators have emerged as a popular tool for the determination of “reactive” analytes due to their great sensitivity toward any kind of external perturbations. They have found application in many fields of applied science enabling relatively easy quantitative and qualitative analyses. In this study influence of pyrocatechol, an important precursor in many organic syntheses, on the pre-oscillatory period of the Bray-Liebhafsky (BL) reaction was examined. The BL reaction was followed by the potentiometric method. In a series of experiments (in a concentration range from 1.5 × 10-5 M to 3 × 10-5 M), pyrocatechol was added 45 minutes after the start of the reaction, causing an immediate appearance of oscillations. For these experimental conditions, the period between the first and second oscillation increases linearly with the added pyrocatechol concentration. The obtained results can be useful for analytical purposes and accordingly, potential determination of unknown pyrocatechol concentration..
Environmental Implications of Financial Development in CEE countries
Authors:   University of Kragujevac, Institute for Information Technologies, Serbia, Veselinović Nevena , Živković Jelena ,   University of Kragujevac, Institute for Information Technologies, Serbia
Published: October 2023

The examination considers the causality between financial development and carbon dioxide (CO₂) emissions in the sample of six Central and Eastern European (CEE) countries in the period range between 2000 to 2020. Utilizing the Dumitrescu and Hurlin panel causality test, the results confirmed a one-way causality, where financial development precedes changes in CO₂ emissions. The observed one-way causality suggests that improvements or advancements in financial development might have implications for environmental sustainability. Additionally, the Westerlund error-correction–based panel cointegration tests reveal cointegration between the variables, indicating a stable equilibrium association among them in the complete sample of countries. As countries strive for economic growth and development, it becomes crucial to consider the environmental consequences and adopt measures that promote sustainable practices. Policymakers and stakeholders must proactively recognize the potentially important role of financial development in shaping environmental outcomes and identify opportunities to effectively integrate sustainable practices into financial and economic strategies.
Antifreeze with coffee taste
Authors:   Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Serbia, Vraneš Milan B. , Papović Snežana M. ,   Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Serbia, Panić Jovana ,   Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Serbia, Borović Teona Teodora V. ,   Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Serbia, Cako Baganj Nikolet A. ,   Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Serbia, Belić Sanja D. ,   Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Serbia, Rackov Sanja ,   Faculty of Technology Novi Sad, University of Novi Sad, Serbia, Gadžurić Slobodan B. ,   Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Serbia
Published: October 2023

This study presents the results of volumetric and viscometric measurements of caffeine solutions in an equimolar mixture of ethylene glycol – water, known as antifreeze. Measurements were made in the temperature range T = (283.15 – 313.15) K and up to a caffeine molality of 0.12 mol∙kg-1. Experimental results are supported by molecular dynamics (MD) computer simulations. The obtained results indicate that water molecules have a dominant role in the solvation of caffeine. At the same time, ethylene glycol acts as a dehydrating agent and promotes the self-aggregation of caffeine and the investigated mixture.
Influence of the ionic liquids-based electrolytes on the tomato (Solanum lycopersicum L.) and cucumber (Cucumis sativus L.) growth, development and oxidative stress
Authors:   University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Serbia, Papović Snežana , Panić Jovana ,   University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Serbia, Borović Teona Teodora V. ,   University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Serbia, Cako Baganj Nikolet ,   University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Serbia, Belić Sanja ,   University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Serbia, Maksimović Ivana ,   University of Novi Sad, Faculty of Agriculture, Serbia, Putnik Delić Marina ,   University of Novi Sad, Faculty of Agriculture, Serbia, Gadžurić Slobodan ,   University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Serbia, Vraneš Milan ,   University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Serbia
Published: October 2023

The increasingly frequent improper disposal of lithium-ion batteries (LIB) is leading to concerns about the environmental consequences. When they are poured out, the flammable solvents from the electrolytes in LIBs are the threatening soil and plant contamination. If these liquids spill or leak from batteries, they could enter the soil through various pathways and contaminate crops such as cucumber and tomato plants, which have extensive root systems that may facilitate the absorption of ILs. After absorption, some electrolyte components could accumulate inside the plants and have toxic effects, potentially harming plant growth and crop fields. This study investigated how spilling electrolytes with varying combinations of ILs, organic solvents, and lithium salts in different concentrations affects the growth and development of tomatoes and cucumbers. Special attention was paid to examining the influence of electrolyte components on aerial parts and/or fruits of these plants and the levels of metabolites involved in antioxidant protection under stressful conditions, such as malonyldialdehyde (MDA). In this work, certain ILs with bis(trifluoromethylsulfonyl)imide, NTf2, anion have a phytotoxic effect, which negatively affects cucumber and tomato growth and development.