bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-term settlement and bearing capacity of foundations adjacent to vertical excavation at various parameters of soil viscosity
Authors: Ter-Martirosyan Zaven G. , Ter-Martirosyan Armen Z. , Vanina Yuliya V.
Published: January 2023

Introduction. When the underground part of a high-rise building interacts with the surrounding soil massif behind the excavation pit, a complex heterogeneous stress-strain state occurs, transforming in space and time — during construction and during the exploitation of the building. Special issues arise when the soil massif is heterogeneous and has rheological properties, and an additional load acts near the pit excavation at the same time.

Materials and methods. For the problem of the stress strain statement of soil with a weight behind the enclosure of a pit with a depth h, taking into account the influence of a distributed load q = const with a width b = 2a at a distance c from the edge of the enclosing structure of the pit, the stress components were obtained using a solution based on the Ribier – Filon trigonometric series. To determine the settlement over time of the foundation near the pit, the A.Z. Ter-Martirosyan’s model was used. To describe shear deformations and the Kelvin – Foigt’s model was used to describe volume deformations, assuming that ε.z(t) = ε.v(t) + ε.γ(t), according to the Henky’s system of physical equations.

Results. An analytical method has been developed for quantifying the settlement of soil bases and foundations of nearby buildings behind the pit over the time. The graphs of the settlement-time with double curvature, as well as the graph of the long-term stability of the base are obtained.

Conclusions. The solutions obtained can be used to determine the long-term settlements and bearing capacity of the foundations of buildings and structures with rheological properties near the pits. The selected geomechanical model of the foundation (its geometric parameters, initial and boundary conditions), as well as the computational model of the soil (linear, nonlinear and rheological) and the type of physical equations (Hooke system or Henky system), significantly affect the type of the settlement-time curve (S–t), as well as the bearing capacity of the soils. Collaborative using of A.Z. Ter-Martirosyan’s rheological model and Kelvin – Foigt’s rheological model makes it possible to obtain settlement-time graphs with double curvature, as well as a graph of the long-term stability of the soil base.
Hydrological and water resources investigations of the Mereb-Gash river basin in Eritrea
Authors: Ghebrehiwot Anghesom A. , Kozlov Dmitry V.
Published: January 2023

Introduction. Adaptation and mitigation of climate change and its consequences through effective water resources management, among others, is essential for achieving sustainable development goals. The construction of water infrastructure facilities and the maintenance of existing ones which can be done with up-to-date hydrological information are required. Therefore, this study aims at obtaining unique information and choosing effective tools for stream flow simulations in Mereb-Gash river basin.

Materials and methods. To this end, physically-based semi-distributed and conceptual models are investigated using climate reanalysis datasets and geomorphologic catchment characteristics. Prior to feeding model forcing variables, their statistical and spatial patterns, methods of potential evapotranspiration estimations, and basin drought conditions are studied. Two or more approaches have been employed for each of these tasks.

Results. GIUH-Nash model has the potential to produce acceptable values in most cases irrespective of sources and resolutions of digital elevation models, but it is found to be sensitive to the type of algorithms selected for stream network generations. The continuous simulation models reveal considerable overestimation of most of the precipitation in the reanalysis datasets, which in turn has a significant effect on other variables, such as potential evapotranspiration and thereby leading to a substantial discrepancy between simulated and observed.

Conclusions. Despite the fact that reanalysis dataset has a great advantage over ground-based observations in terms of their simplicity and accessibility, the research results have shown the need for a critical attitude to both sources of initial data. To minimize the uncertainties of mathematical models and thereby to improve modeling capabilities, there is no qualitative alternative to restoring existing as well as new ground-based observation stations.
Research on the potential demand for non-commercial rental housing
Authors: Magina Anastasia I. , Mishlanova Marina Yu.
Published: January 2023

Introduction. Existing market, regulatory, organizational and economic mechanisms do not cope with the urgent tasks in the housing sphere of Russia. Inaccessibility of housing purchase and mortgage lending for a large part of the population leads to the need to seek other forms of solving the housing problem, in particular, to realize this need by renting housing. The article is devoted to one of the socio-economic objectives of national development — the formation of a civilized market of non-commercial rental housing.

Materials and methods. The method of sociological survey used for students studying in Moscow allowed us to obtain the opinion of people who will stay to work in this region in the future. To determine the parameters of the sociological survey, the study used the basic principles of the quota sampling method with interrelated parameters. When processing the obtained information, the well-known methods of culling the results of the survey, the analysis of linear distributions, correlation analysis were used. Tables, pie charts and histograms were used to visualize the results of the obtained data, which allow making a comparative analysis.

Results. In order to conduct a sociological survey, the research program presented in the article was developed. The authors studied the ranked list of consumers of the residential real estate rental market. The assessment of the segments of social and non-commercial rental housing and the prospects for their development is presented. Among the consumers the authors have reasonably singled out young professionals and characterized this group from the position of potential demand on the market of non-commercial rental housing. The authors identified the socio-economic problem and determined the direction of the study — the consideration of future university graduates as potential consumers of rental housing. In addition, the study allowed the authors to identify the directions of formation of a civilized housing rental market, in particular, the prospects of state regulation.

Conclusions. As a result of the study the availability and options for future graduates to realize the need for housing, the characteristics of the potential demand of future graduates for non-profit housing rental were investigated. The generalization of the results allowed the authors to identify the main directions of development of the market of non-commercial rental housing.
Social factors affecting relapse of severe mental illness: A qualitative analysis of healthcare team's perceptions
Authors: Seyedfatemi Naima , Saber Saman
Published: January 2023

Objective: Relapse is a challenge for patients with severe mental illness (SMI). The purpose of present study was to explain the health care team’s perception of social factors affecting SMI relapse.

Methods: In this qualitative content analysis study, semi-structured interviews have been conducted with 23 members of healthcare team. Content analysis was used to categorize the data.

Results: The social factors affecting the relapse of SMI could be classified in three categories of community-related factors, cultural factors, and family-related factors. The first category included low socioeconomic status, lack of community support for SMI patients, and insufficient awareness of community about SMI. The second category included false beliefs and misconceptions, and negative attitudes towards SMI. The third category also included dysfunctional family and non-supportive family.

Conclusion: In order to deal with cultural misconceptions that lead to the relapse of SMI, it is necessary to implement culture-based interventions to correctly confront negative attitudes and stigmatized beliefs and fight against cultural taboos that govern the phenomenon of SMI relapse in Iran. It seems that the implementation of family-centered interventions for the family of patients with SMI can reduce the burden of family-related factors in disease relapse.
Fontes de concepções de avaliação educacional por três professores de matemática do ensino secundário geral
Authors: Chicote Rosalino Subtil , Deixa Geraldo Vernijo
Published: January 2023

A pesquisa visou revelar a fonte da concepção da avaliação educacional de três professores de matemática do Ensino Secundário Geral. Ela foi de abordagem qualitativa e os dados foram produzidos por meio de uma entrevista semiestruturada. A Análise Textual Discursiva serviu para análise dos dados. Dos resultados, não foram identificadas novas concepções de avaliação educacional, prevalece a concepção de avaliação como medida das aprendizagens. Conclui-se que as concepções desses professores possuem duas fontes: formação de professores e experiências quotidianas. Sugere-se a incorporação de Avaliação em Matemática como disciplina na estrutura curricular do curso de formação de professores de matemática.
Males da exclusão: o SANAR e o combate a doenças negligenciadas em Pernambuco
Authors: Da Silva José Alexandre , Da Silva Breno Avelino , Batista Danillo Rafael
Published: January 2023

Em que medida o programa SANAR reduziu a incidência de doenças negligenciadas em Pernambuco? Segundo o Governo do Estado, o SANAR se configurou como uma experiência bem-sucedida. Porém, os poucos estudos sobre essa política não necessariamente corroboram esse otimismo. Nesse trabalho, examinamos o período de 2001-2014, tendo os 184 municípios pernambucanos como unidade de análise. O objetivo é realizar uma avaliação de impacto do programa SANAR em sua primeira etapa. Nossa hipótese é que o programa reduz significativamente as taxas de incidência da tuberculose e da esquistossomose. Para testá-la, utilizamos o método de diferença em diferença com escore de propensão e de controle sintético. Os principais resultados são: 1) no período após a implementação do programa, o grupo tratado (de municípios assistidos pelo programa) apresenta maior incidência e maior abandono ao tratamento de tuberculose; 2) o grupo tratado apresenta maior incidência e ausência de tratamento de esquistossomose; 3) a variável tratamento não apresenta significância estatística em nenhum modelo estimado e 4) não há indícios de eficácia do programa.
A aplicabilidade do direito ao esquecimento às pessoas condenadas penalmente
Authors: Xavier José Tadeu Neves , Santos Ana Luiza Liz dos
Published: January 2023

O presente estudo apresenta breves considerações sobre o reconhecimento do direito ao esquecimento às pessoas condenadas criminalmente. Como procedimento metodológico, utilizou-se o método de abordagem hipotético-dedutivo e técnica de pesquisa bibliográfica e jurisprudencial. Diante do desenvolvimento tecnológico e do avanço da Sociedade de Riscos e da Sociedade da Informação, o direito ao esquecimento passa a receber atenção do pensamento jurídico, com destaque especialmente na seara penal, isto é, como instituto de ressocialização das pessoas condenadas criminalmente. O objetivo geral, portanto, é estudar a tutela dos bens jurídicos diante do atual contexto da Sociedade de Riscos e da Sociedade da Informação, a partir da transformação que a tecnologia tem causado na modernidade. Como objetivos específicos, tem-se: observar algumas especificidades da Sociedade de Riscos e da Sociedade da Informação; explanar breves considerações sobre a tutela do bem jurídico do qual decorre o direito ao esquecimento; estudar o reconhecimento do direito ao esquecimento para as pessoas condenadas criminalmente, inclusive com base em sua origem, que é vinculada ao Direito Penal; e verificar a aplicabilidade prática do direito ao esquecimento em matéria penal, a partir do posicionamento do Superior Tribunal de Justiça sobre a temática. Conclui-se que a Sociedade de Riscos e a Sociedade da Informação inserem diversos bens jurídicos em condição de vulnerabilidade, de modo que, especificamente o direito ao esquecimento pode figurar como suporte fundamental para a consumação do instituto da ressocialização criminal.
O reflexo da seletividade do sistema de justiça criminal na composição dos bancos de perfis genéticos
Authors: Nascimento Deise dos Santos , Borges Clara Maria Roman
Published: January 2023

O presente artigo analisa os impactos dos bancos de perfis genéticos sobre minorias sobrerrepresentadas no sistema de justiça criminal brasileiro. O objetivo é investigar de que maneira essa tecnologia reforça o controle penal de grupos já marginalizados nesse sistema. Para esse fim, inicialmente são examinados os critérios das políticas de coletas de DNA na criação suspeitos, bem como os reflexos dessas políticas em minorias desproporcionalmente representadas no sistema de justiça criminal. Na sequência, são abordadas as possibilidades de políticas mais inclusivas de coletas de DNA para, enfim, discutir os impactos do policiamento genético no projeto de seletividade que os bancos tendem a reproduzir na construção de suspeitos racializados. A pesquisa é exploratória, mediante técnica de pesquisa bibliográfica e documental, por intermédio de uma abordagem qualitativa, com análise teórico-narrativa. Ao final, os resultados indicaram que os bancos de perfis genéticos reforçam o controle penal de jovens, negros e pobres ao (re)estigmatizá-los e mantê-los como alvos principais do sistema de justiça criminal, que inevitavelmente refletem as disparidades da criminalização secundária em sua composição. Diante disso, argumenta-se que os debates atinentes à política de coleta de DNA para fins de identificação criminal e armazenamento em bancos de perfis genéticos devem incluir o impacto desproporcional em minorias racialmente criminalizadas.
AS CIDADES DOS PUNKS
Authors: Bittencourt João
Published: January 2023

A proposta desse artigo é problematizar a relação entre o Punk e a cidade, mostrandocomo o surgimento desse estilo de vida jovem foi fortemente influenciado pelasdinâmicas da vida urbana, podendo ser classificado como uma forma sui gêneris decitadinidade. É por meio do caminhar na urbe que os punks expõem seus valores estéticose visões de mundo, tensionando uma percepção higienizada e ordeira que busca impedir(ou regulamentar) o nomadismo dos indesejáveis. A cidade se apresenta para os punkscomo um paradigma fundante de suas experiências citadinas que ganha forma a partir daprodução de narrativas orais e imagéticas, expressadas em letras de músicas, pichações,poesias, etc. É a partir desse material que extrairemos os sentidos mobilizados por essesatores "sobre a cidade”, sobre "estar na cidade” e sobre o "fazer-cidade".
UM CASEBRE JUNTO À CADEIA: Sociabilidade entre figuras sociais antagônicas
Authors: Meira Bonfim Mantellatto Laura
Published: January 2023

Por meio de um relato de história oral, este artigo recupera detalhes da forma de sociabilidade, e os sentidos atribuídos à vida cotidiana, no contexto histórico das décadas de 1960 a 1980. Quem nos conta esta história é Lourdes, mulher que, em 1964, logo após o casamento com um policial militar, mudou-se com ele para um casebre anexo à cadeia de madeira, na pequena cidade de Ivaiporã/PR. Lourdes relata a formação de um relacionamento de amizade com os presos, com quem partilhava, inclusive, a cozinha do casebre, onde alguns dos homens eram encarregados pelo preparo da refeição para o todo o grupo encarcerado. Além deles, Lourdes também se aproxima de mulheres da zona de meretrício, as quais, quando presas, ficavam sob seus cuidados. O artigo discute as transformações sociais ao longo processo de modernização de Ivaiporã, com ênfase na política de administração dos espaços e possibilidades de arranjos interpessoais ao longo do período ditatorial, responsável por reprimir encontros e formas de associação variadas.

Palavras-chaves: História oral. Sociabilidade. Modernização capitalista. Ditadura militar.
ATORES URBANOS, TRAJETÓRIAS E PROJETOS DE VIDA NA CIDADE: Abordagens etnográficas em perspectiva
Authors: Ferro Lígia , Abalos Júnior José Luís , Marmanillo Pereira Jesus
Published: January 2023

Este artigo reflete sobre o processo de organização do dossiê denominado “AtoresUrbanos: estéticas, trajetórias e projetos de vida na cidade” publicado em dezembro de2022 pela revista Iluminuras, vinculada ao Programa de Pós-Graduação em AntropologiaSocial da Universidade Federal do Rio Grande do Sul (PPGAS/UFRGS). Desde omomento da concepção do dossiê procuramos construir uma proposta de chamada quedialogasse com as temáticas dos atores urbanos, com foco especial nos processos deinterlocução entre pesquisadores e parceiros de pesquisa no espaço da cidade. Nestesentido a proposta do dossiê se mostrou um espaço privilegiado para reflexão sobrealteridades privilegiadas na pesquisa social, e mais especificamente nas práticasetnográficas urbanas. Começamos o texto abordando os conceitos chaves que fizeramparte do processo de editoração, como atores sociais, etnografia urbana e projetos de vida.Posteriormente indicamos três eixos de leitura identificados como artes e intervençõesurbanas; cidades, imagens e sociabilidades e, por fim, migrações e trabalho. Concluímosabordando que as conexões criativas dos trabalhos com eixos citados nos ajudam a pensarnovas parcerias de pesquisa e formas de contato com subjetividades na cidade no contextoda pesquisa em ciências sociais.
CICLOS ELEITORAIS E PARTIDÁRIOS E INTERAÇÃO ESPACIAL NAS DESPESAS EM SAÚDE E SANEAMENTO MUNICIPAIS (1998-2012)
Authors: GOMES BRUNO SILVA DE MORAES , Bastos Suzana Quinet de Andrade , Almeida Eduardo Simões de
Published: January 2023

O trabalho investiga evidências de ciclos políticos e eleitorais nas despesas com a função saúde e saneamento. O modelo de painel dinâmico espacial propicia observar se a hipótese de ciclos eleitorais e partidários é plausível ou não, ou seja, seocorre o aumento das despesas com saúde e saneamento nos anos da eleição municipal e quais os partidos que mais gastam com saúde e saneamento. Identifica-se que o padrão dessas despesas é influenciado pelo comportamento das despesas dos municípios vizinhos. Nota-se a presença do efeito spillover, pois os governantes reduzem suas despesas com saúde e saneamento ao observarem que os vizinhos aumentam as despesas.
Uma Curva Elíptica sobre F_23
Authors: Apaza Rodriguez Jaime Edmundo
Published: January 2023

Neste trabalho apresentamos um modelo de uma Curva Elíptica definida sobre um corpo primo. Nas primeiras seções fazemos um estudo preliminar das Curvas Elípticas e dos Corpos Finitos, em especial dos Corpos de Galois, e é definida a operação de adição na Curva Elíptica (dependendo da característica do corpo em questão). Na última seção apresentamos o modelo de uma Curva elíptica definida sobre o corpo F_23.
Aprendizagem baseada em projetos: possibilidade didática de implantação de hortas escolares
Authors: Santana Viviane Mendes , Silva Gabriele Marisco da
Published: January 2023

A aprendizagem baseada em projetos (ABPr) trata-se de uma estratégia ativa caracterizada principalmente pelo incentivo à autonomia do aluno e à realização de atividades coletivas. Partindo disso, o presente estudo objetivou identificar as opiniões e as possibilidades de engajamento de professores sobre as estratégias ativas e uso da ABPr para implantação de projetos de hortas escolares. Os dados foram obtidos a partir de um processo formativo com professores da educação básica. Os resultados foram analisados por meio da análise de conteúdo. Identificou-se que os professores conhecem diferentes estratégias ativas de ensino, porém possuem algumas dificuldades na utilização, sendo justificadas pela falta de material de apoio e de capacitação docente. A maioria afirmou conhecer a ABPr, citando que é uma estratégia que estimula o pensamento crítico, realização de trabalho coletivo, criatividade, respeito e resolução de problemas. Para os professores dessa pesquisa, tanto docentes quanto discentes apoiariam a implementação de um projeto utilizando os preceitos da ABPr na sua escola com a temática horta, o qual trará benefícios importantes para o processo de ensino-aprendizagem, como incentivar a autonomia e o protagonismo do aluno.
القيم النضالية الشخصية الرئيسية في رواية في سبيل التاج لمصطفي لطفي المنفلوطي: تحليل سوسيولوجي الأدب
Authors: Vita Diana Ermawati
Published: January 2023

The problem in this research is the value of the struggle of the main character contained in the novel Fi Sabili at-Taj by Mushtafa Luthfi al-Manfaluthi.  The purpose of this research is to find out, describe, and analyze the values ​​of the struggle of the main character in the novel Fi Sabili at Taj by Mushtafa Luthfi al Manfaluthi in solving the problems at hand.  Based on the source of the data studied, the researcher found the value of the struggle shown by the main character.  The results of this study are that there are eight values ​​of struggle, namely the value of self-sacrifice, the value of unity, the value of respect, the value of patience and the spirit of never giving up, the value of cooperation, the value of love for the country, the value of hard work and the value of national spirit.  The novel Fi Sabili at-Taj contains a good story about the struggle to defend the nation and state so that it can build the character of defenders of the nation and state.
خطبة طارق بن زياد قبل فتح الأندلس (دراسة تحليلية التأويلية)
Authors: Anas Rulloh Mohammad
Published: January 2023

This study discusses the meaning and interpretation in the text of Tariq bin Ziyad's sermon before the conquest of Andalusia with the interpretation or hermeneutic analysis method. The purpose of this study is to uncover the explicit and implicit meanings of Tariq bin Ziyad's sermon text before the conquest of Andalusia. This research uses the type of library research, because most of the data and sources of this research come from books and documents. The researcher uses the document study method in his research as a data collection method. As for verifying the validity of the data, the researchers used triangulation techniques. Using descriptive analysis in analyzing the data after analyzing the interpretation in the text of Tariq bin Ziyad's sermon before the conquest of Andalusia. We know that this sermon contains motivation, advice and wisdom.
Reflections of Urartian Cities in Rural Areas: Potters’ Marks and Red Burnished Wares from Murat Höyük and Murat Tepe in Bingöl, Turkey
Authors: DANIŞMAZ Harun , ÖZDEMİR Abdulkadir
Published: January 2023

This study discusses previously unpublished examples of Urartian red burnished pottery and potters’ marks found during excavations at Murat Höyük and Murat Tepe in East Anatolia. Findings discussed in this study provide tangible evidence for the cultural influence of Urartian cities on rural areas.

Murat Höyük and Murat Tepe are located on the northeast bank of the Murat River, at the point where the river meanders east. The two adjacent sites derive their name from this river. Excavations at Murat Tepe revealed two settlement levels dating to the Medieval Period and the Iron Age. At nearby Murat Höyük, Medieval, Middle Iron Age, Early Iron Age and Early Bronze Age levels were documented. A few examples of potters’ marks and red burnished ware sherds were found at both sites. In general, current research suggests that red burnished ware and ceramic vessels bearing potters’ marks were used in elite and palatial contexts in Urartian cities. Therefore, the attestation of these assemblages at rural sites such as Murat Höyük and Murat Tepe in a remote region away from Urartian cities, provides significant information on the kingdom’s cultural influence on rural areas.
Middle Ear Resonance Values of Patients with Temporomandibular Disorder
Authors: Ekşi Beyza , Konukseven Bahriye , Gözler Serdar
Published: January 2023

Objective: This study aimed to investigate the effect of the disease on
the middle ear resonance frequencies with wide-band tympanometry in the
people with temporomandibular disorder (TMD). Methods: A total of 40
individuals (24 patients, 16 control groups), 18 years of age and older,
25 females and 15 males, were included in the study. For the patients
who came to the Oral Diagnosis Department of XXXX University with the
complaint of TMD, the patient’s history and detailed examination were
taken by the specialist dentist. Pure tone audiometry (125-8000 Hz
air-way, 250-4000 Hz bone conduction thresholds) and speech audiometry,
acoustic immitance and middle ear resonance measurements, outer ear
resonance test were applied. Results: TMD ipsilateral and contralateral
middle ear resonance values for each individual of the study group and
control group and statistical data were determined. No difference was
observed in the mean values of the 3 groups for middle ear resonance.
However, there was a significant difference between the middle ear
resonance values of the TMD ipsilateral and control groups. Conclusion:
In a patient population with TMD the increase in middle ear RF values in
the ipsilateral ears of the lesion may provide evidence of an increase
in the stiffness of the middle ear system, offering a new perspective on
the pathophysiology of the disease. KEY POINTS 1) Middle ear canal
resonance frequency can be determined with wideband tympanometry (WBT).
2) There was no difference in the mean values of the three groups for
the ipsilateral of the temporamandibular disorder, the contralateral of
the temporamandibular disorder and the middle ear resonance values of
the control group. 3) It was observed that there was a significant
difference between the ipsilateral resonance values of the TMD patient
group and the middle ear resonance values of the control group. 4) This
study aims to present additional findings and methods for differential
diagnosis by showing the differences between clinical tests applied to
individuals with TMD and middle ear findings of normal individuals. 5)
This study will also provide the first findings of minor middle ear
pathology in patients with TMJ disorders by WBT.
Cytosolic protein delivery using ultrasound-guided vaporization of perfluorocarbon nano-droplets
Authors: Yamaguchi Satoshi , Kisaka Miho , Higashi Kotaro , Ishijima Ayumu , Azuma Takashi , Nakagawa Keiichi , Shibasaki Yoshikazu , Sakuma Ichiro , Okamoto Akimitsu
Published: January 2023

Ultrasound-guided protein delivery is promising for site-specific
control of cellular functions in the deep interior of the body in a
noninvasive manner. Herein, we propose a method for cytosolic protein
delivery based on ultrasound-guided intracellular vaporization of
perfluorocarbon nano-droplets. The nano-droplets were conjugated with
cargo proteins through a bio-reductively cleavable linker and introduced
into living cells via antibody-mediated binding to a cell-surface
receptor, which gets internalized through endocytosis. After the cells
were exposed to ultrasound for endosomal escape of proteins, the
ultrasound-responsive cytosolic release of a cargo enzyme was confirmed
by visualizing the hydrolysis of the fluorogenic substrate using
confocal microscopy. Moreover, a significant decrease in cell viability
was achieved via the release of a cytotoxic protein in response to
ultrasound treatment. The results of this study provide the proof of a
principle that protein-conjugated nano-droplets can be used as carriers
in ultrasound-guided cytosolic delivery of proteins.
NLRP2 in health and disease
Authors: Zhang Tongtong , Xing Fei , Qu Mingcui , Yang Zhihu , Liu Yafei , Yao Yongchao , Xing Na
Published: January 2023

NLR family pyrin domain containing 2 (NLRP2) is a novel member of the
Nod-like receptor (NLR) family. However, our understanding of NLRP2 has
long been ambiguous. NLRP2 may have a role in the innate immune
response, but its specific  functions remain controversial.
Although NLRP2 can initiate inflammasome and promote inflammation, it
can also downregulate inflammatory signals. Additionally, NLRP2 has been
reported to function in the reproductive system and shows high
expression in the placenta. However, the exact role of NLRP2 in the
reproductive system is unclear. Here, we highlight the most current
progress on NLRP2 in inflammasome activation, effector function, and
regulation of nuclear factor-κB. And we discuss functions of NLRP2 in
inflammatory diseases, reproductive disorders, and the potential
implication of NLRP2 in human diseases.
Chronic Degradation of Seasonally Dry Tropical Forests Increases the Incidence of Genotoxicity in Birds
Authors: Solórzano Gabriela Cevallos , Ordóñez-Delgado Leonardo , Espinosa Carlos Ivan , Jara Paul , Tomás Gustavo , Moscoso Natalia Bailón
Published: January 2023

Environmental stress as a consequence of anthropic pressures can affect
the physiological condition of animals and cause damage to their DNA.
Multiple studies have shown genotoxic effects of different pollutants;
however, to our knowledge, the impact of environmental stress on genetic
damage has been scarce explored. In some stressful ecosystems, such as
seasonally dry tropical forests, the combined effects of anthropogenic
activities and ongoing global changes cause increased environmental
stresses that could trigger physiological and genetic effects on
biodiversity. In this study, we evaluated the changes in the prevalence
of genotoxic damage to birds in three states of forest degradation in
the Tumbesian Region of Western Ecuador. We used the blood samples of 52
bird species to determine the frequency of micronucleus and nuclear
abnormalities in the erythrocytes. Our results showed a significant
effect of forest degradation in the proportion of micronucleus and
nuclear abnormalities at the community level, localities with higher
degradation showed higher levels of abnormalities. However, when
analyzing the dominant species, we found contrasting responses. While
Amazilis amazilia and Lepidocolaptes souleyetii showed a reduction in
the proportion of nuclear abnormalities from the natural to
shrub-dominated localities, Troglodytes aedon and Polioptila plumbea
showed an increase. We concluded that the degradation process of these
tropical forests increases the stress on the bird community generating
genotoxic damage to the bird community. Bird responses seem
species-specific, which could explain the differences in changes in bird
composition reported in other studies.
The Main Himalayan Thrust beneath Nepal and Southern Tibet illuminated by seismic ambient noise and teleseismic P wave coda autocorrelation
Authors: Thapa Hari Ram , Pachhai Surya , Aoudia Abdelkrim , Manu-marfo Daniel , Priestley Keith F. , Mitra Supriyo
Published: January 2023

Nepal is an actively deforming region due to its tectonic setting that
hosts many destructive earthquakes including the recent 2015 Mw 7.8
Gorkha earthquake. To better understand the physics of earthquakes and
their precise location as well as monitoring of seismicity and real-time
seismic hazard in the region, a highly resolved 3-D structure of the
crust is essential. This study presents a new 3-D S-wave velocity
structure of the crust using ambient noise tomography (ANT). This study
further constrains the discontinuities beneath Himalaya Nepal using
teleseismic P-wave coda autocorrelation. The results from the P-wave
coda autocorrelation identify major seismic discontinuities in the crust
including the Main Himalayan Thrust (MHT). The MHT with two ramps
correlates well with a low S-wave velocity layer obtained from the ANT.
The first ramp agrees with the duplex structure in the MHT beneath
Lesser Himalaya while the second connects flat low velocity beneath High
Himalaya to a broad low-velocity zone beneath South Tibet. The geometry
and extent of the High Himalaya low-velocity layer mimics the
decollement coupling zone inferred from GPS data with widths of 50-70 km
north of the nucleation of the 2015 Mw 7.8 Gorkha earthquake and 90-100
km north of the source of the Mw 8.4 1934 earthquake. The occurrence of
millenary Mw>9.0 earthquakes in Central and Eastern Nepal
would require either a wider coupling low velocity zone compared to the
ones identified in this work or the involvement of southernmost Tibet
low velocity decoupling zone so to store enough elastic energy.
Classification of Solar Flares using Data Analysis and Clustering of Active Regions
Authors: Baeke Hanne , Amaya Jorge , Lapenta Giovanni
Published: January 2023

We devised a new data analysis technique to identify the threat level of
solar active regions by processing a combined data set of magnetic field
properties and flaring activity. The data set is composed of two
elements: a reduced factorization of SHARP properties of the active
regions, and information about the flaring activity at the time of
measurement of the SHARP parameters. Machine learning is used to reduce
the data and to subsequently classify the active regions. For this
classification we used both supervised and unsupervised clustering. The
following processing steps are applied to reduce and enhance the SHARP
data: outlier detection, redundancy elimination with common factor
analysis, addition of sparsity with autoencoders, and construction of a
balanced data set with under- and over-sampling. Supervised clustering
(based on K-nearest neighbors) produces very good results on the strong
X- and M-flares, with TSS scores of respectively 93% and 75%.
Unsupervised clustering (based on K-means and Gaussian Mixture Models)
shows that non-flaring and flaring active regions can be distinguished,
but there is not enough information in the data set for the technique to
identify clear differences between the different flaring levels. This
work shows that the SHARP database lacks information to accurately make
flaring predictions: there is no clear hyperplane in the SHARP parameter
space, even after a detailed cleaning procedure, that can separate
active regions with different flaring activity. We propose instead, for
future projects, to complement the magnetic field parameters with
additional information, like images of the active regions.
Selection of a stress-based soil compaction test to determine potential impact of machine wheel load
Authors: Ali Aram , Bennett John , Roberton Stirling , Krwanji Diman , Zhu Yingcan , West David
Published: January 2023

The use of heavy machinery is increasing in agricultural industries in
particular cotton farming systems, which induces an increased risk of
soil compaction and yield reduction. Hence, there is a need for a
technical solution to use available tools to measure projected soil
compaction due to farm machinery traffics. The aim of this work was to
compare the effects of static and dynamic loads on soil compaction. In
this study, three vertosols (common soil for cotton production) were
selected to examine soil compaction under a range of static and dynamic
loads using uniaxial compression equipment and a modified proctor test,
respectively. In general, soils behaved similarly under static and
dynamic loads with no significant difference between bulk density values
for all moisture contents with a high index of agreement (d=0.96, RMSE=
0.056). The results further indicate better agreement between soil
compaction for static and dynamic loads Uniaxial compression test
(static loads) produced higher compaction compared to the modified
proctor test (dynamic loads) in particular at moisture contents lower
than the plastic limit condition. The variation in soil compaction for
static and loads was often evident for loads ≥600 kPa, with the highest
soil compaction induced under loads ≥1200 kPa. The findings of this
study confirm the suitability of a modified proctor method to assess
soil compaction as an alternative tool under a range of moisture
contents and machinery loads for vertosols.
Harnessing Underutilized Gene Bank Diversity and Genomic Prediction of Cross Usefulness to Enhance Resistance to Phytophthora cactorum in Strawberry
Authors: Jiménez Nicolás , Feldmann Mitchell , Famula Randi , Pincot Dominique , Bjornson Marta , Cole Glenn , Knapp Steven
Published: January 2023

The development of strawberry (Fragaria × ananassa)
cultivars resistant to Phytophthora crown rot (PhCR), a devastating
disease caused by the soil-borne pathogen Phytophthora cactorum,
has been challenging, partly because resistance phenotypes are
quantitative and only moderately heritable. To develop deeper insights
into the genetics of resistance and build the foundation for applying
genomic selection, a genetically diverse training population was
screened for resistance to California isolates of the pathogen. Here we
show that genetic gains in breeding for resistance to PhCR have been
negligible (3% of the cultivars tested were highly resistant and none
surpassed early twentieth century cultivars). Narrow-sense heritability
for PhCR resistance ranged from 0.35-0.57. Using multivariate GWAS, we
identified a large-effect locus (predicted to be RPc2) that appears to
be ubiquitous, slowed symptom development, explained 43.6-51.6% of the
genetic variance, was necessary but not sufficient for resistance, and
was strongly associated with calcium channel and other genes with known
plant defense functions. The addition of underutilized gene bank
resources to our training population doubled additive genetic variance,
increased the accuracy of genomic selection, and enabled the discovery
of individuals carrying favorable alleles that are either rare or not
present in modern cultivars. The incorporation of an RPc2-associated SNP
as a fixed effect increased genomic prediction accuracy from 0.40 to
0.55. Finally, we show that parent selection using genomic-estimated
breeding values, genetic variances, and cross-usefulness holds promise
for enhancing resistance to PhCR in strawberry.
Production portfolio analysis of companies form the field of forestry: Case study
Authors: Keca Ljiljana , Blanusa Iliana , Marceta Milica
Published: January 2023

In the paper, through a case study of a company from the field of forestry,
an analysis of the product portfolio was carried out and the position of
each product was defined within the BCG (growth/share) matrix. As well as
that, based on the conducted SWOT analysis, the company?s strengths, and
weaknesses, as well as opportunities and threats from the envi?ronment, were
identified. The goal of the paper is to identify the best way to use
financial resources and define the need to introduce new products, in order
to assess the potential and market opportunities of the company ?Gradina
Sistem? d.o.o. from Temerin. The purpose of the work is to define directions
for (re)directing financial resources towards more sustainable and
profitable ones based on the established positions of individual products.
The subject of the research is the company ?Gradina Sistem? d.o.o. from
Temerin, its current business system and production portfolio, which is
mostly focused on: wooden flooring, pallets and crates made of poplar.
How do we SEE digital platform workers’ skill patterns? Evidence from South-Eastern Europe
Authors: Ivanovic Vladan , Andjelkovic Branka , Jakobi Tatjana , Kalinic Zoran , Radonjic Ljubivoje , Colovic Petar
Published: January 2023

The study aims to identify and describe the most relevant professional skill patterns among the digital platform workers from the selected Southeastern European (SEE) countries. Such orientation is based on the relatively modest presence of SEE countries in large pan-European studies, and on the lack of information regarding the applicability of existing online job taxonomies in observed countries. Applying a topic approach as a natural language processing technique, we analyzed the sets of self-reported skills provided by digital platform workers registered at the Upwork platform. Seven distinctive skill profiles were extracted, which only partly overlapped with the standard Oxford?s Online Labour Index of digital job taxonomy. Results are indicating clear distinctions between highly specialized and general job categories, and between creative and technical professions. Mapping of the skills and national affiliations reveal differences between EU and non-EU countries in the region regarding professional inclinations. Partly in line with the findings of previous studies, the results pave the way for future research on this topic.
Computational Tools and Experimental Methods for the Development of Passive Prosthetic Feet
Authors:   , Morgan Benjamin W.
Published: January 2023

Modern prosthetic foot designs are incredibly diverse in comparison to what was o↵ered to amputees at the turn of the millennium. Powered ankles can supply natural levels of joint torque, whilst passive feet continue to optimise for kinematic goals. However, most passive feet still do not solve the issue of unhealthy loads, and an argument can be made that optimisation methods have neglected the less active and elderly amputee. This thesis creates a framework for a novel approach to prosthetic foot optimisation by focusing on the transitionary motor tasks of gait initiation and termination.An advanced FEA model has been created in ANSYS® using boundary con-ditions derived from an ISO testing standard that replicates stance phase loading. This model can output standard results found in the literature and goes beyond by parameterising the roll-over shape within the software using custom APDL code. Extensive contact exploration and an experimental study have ensured the robustness of the model. Subject force and kinematic data can be used for speciﬁc boundary conditions, which would allow for easy adaptation to the transitionary motor tasks.This FEA model has been used in the development of prosthetic experiment tool, which can exchange helical springs to assess e↵ects of small changes in sti↵-ness on gait metrics. A rigorous design methodology was employed for all compo-nents, including parametric design studies, response surface optimisation, and ISO level calculations. The design has been manufactured into a working prototype and is ready for clinical trials to determine its eﬃcacy.The conclusion of this framework is in the development of an experimental method to collect subject data for use in the models. A pilot study uncovered reliable protocols, which were then veriﬁed with ANOVA statistics. Proportional ratios were deﬁned as additions to metric peak analyses already found in the liter-ature. These tools are ready for deployment in full clinical trials with amputees, so that a new prosthetic optimisation pathway can be discovered for the beneﬁt of less active or elderly amputees.
Effect of Viscosity Contrast and Wetting on Frictional Flow Patterns
Authors:   , Zhang Dawang
Published: January 2023

Multiphase flows involving two fluids and a granular material occur in such diverse sce-narios as mud and debris flows, methane venting from sediments, degassing of volatiles from magma, and the processing of granular and particulate systems in the food, pharmaceutical, and chemical industries. The presence of the granular material introduces solid friction as a governing force in the dynamics, alongside viscosity and capillarity. This multitude of interacting elements and forces can give rise to instabilities and the emergence of patterns, making these multiphase frictional flows inherently difficult to predict or control. We refer to these granular-fluid-mixtures as frictional fluids.We explore here systematically the competition between frictional, viscous, and capillary forces in frictional fluid flows. Viscously stable (more viscous invading fluid) and unstable (more viscous defending fluid) scenarios are investigated, and we study wetting conditions from drainage (grains wetted by defending fluid), through mixed-wet, to imbibition (grains wetted by invading fluid). The emerging flow patterns are studied using both experiments and simulations. Firstly, the effect of viscous stabilization on frictional finger pattern formation is discovered. When the flow is viscously stable, increasing the viscous force leads to a striking transition from the growth of one solitary finger to the simultaneous growth of multiple, wandering fingers to the axisymmetric growth of a radial spoke pattern as the flow is increasingly viscously stabilised. When the flow is viscously unstable, in contrast, the invasion patterns transition from frictional fingering to classical viscous fingering as viscous force increases beyond a critical fluidisation threshold. Later, the effects of parameters such as plate spacing and its gradient along the cell, and the tilt angle of the cell, on the pattern formation is studied. Furthermore, viscously unstable fracturing in drainage is studied. A small change on the volume fraction of granular material which govern the friction stress in the system, can convert the invasion from bulldozing fractures to pore invasion. At high air pressure, the fractures form a radially symmetric pattern where the fractures also gradually widen over time. Finally, viscously stable displacement from imbibition through mixed-wet to drainage is explored. Here, three types of invasion dynamics happens simultaneously or sequentially: pore invasion, capillary bulldozing and erosion, and five regimes of invasion patterns are identified: (I) pure pore invasion, (II) pure capillary bulldozing, (III) capillary bulldozing followed by pore invasion, (IV) pore invasion followed by erosion and (V) capillary bulldozing followed by pore invasion and erosion. These are caused by the relative importance of capillarity, friction and viscous pressures determined by the experimentally controlled variables.
Coluna Degenerativa – Novas Evidências
Authors:   Serviço de Medicina Física e de Reabilitação, Centro Hospitalar e Universitário de Coimbra, P Coelho Alexandra Isabel , Santos Faria João ,   Serviço de Medicina Física e de Reabilitação, Centro Hospitalar e Universitário de Coimbra, HovenKamp Carla ,   Serviço de Medicina Física e de Reabilitação, Centro Hospitalar e Universitário de Coimbra, Branco João Paulo ,   Faculdade de Medicina da Universidade de Coimbra
Published: January 2023

Low back pain is a frequent complaint in the general population, that may also affect veteran athletes. Understanding the etiology of low back pain is essential for a correct therapeutic orientation, which should include behavioral changes and a rehabilitation program. In some cases, it may be necessary to associate pharmacological therapy, minimally invasive procedures, or even surgical interventions. Minimally invasive procedures include a variety of techniques and procedures that have demonstrated low to moderate degrees of evidence in pain management. As they are not risk free and have a limited duration of action, they should be reserved for cases refractory to conservative treatment.
Entrevista
Authors:   Liga de Portugal, Moreira André
Published: January 2023

“A área Saúde da Liga Portugal surgiu inicialmente como uma necessidade dos departamentos clínicos das sociedades desportivas.... Entendemos que a saúde e segurança dos jogadores e dos demais intervenientes no jogo deve ser uma prioridade. Os departamentos clínicos dos clubes têm de ser ouvidos e devem participar ativamente nas orientações desta área.... Procuraremos valorizar as competências clínicas dos clubes, otimizar os recursos humanos e materiais, assim como aumentar a homogeneidade dos diversos departamentos clínicos numa abordagem de sa.de multidisciplinar. ... Apenas com profissionais qualificados e atualizados com as exigências do futebol profissional se pode estar devidamente preparado para a prevenir e tratar adequadamente lesões dos jogadores, reduzir os tempos de return-to-play, potenciar o seu rendimento desportivo e lidar com qualquer emergência médica que possa surgir. ... ao nível das infraestruturas também pretendemos implementar a categorização, por níveis, dos departamentos clínicos. Esta categorização terá uma série de requisitos que são muito objetivos e que incluirá, por exemplo, a avaliação dos recursos humanos, as infraestruturas e equipamentos, a capacidade instalada para lidar com emergências médicas e a atualização ou formação dos profissionais de saúde. ...”