bluuebunny/crossref_metadata_2025 huggingface dataset:
TRANSPARANSI PENGELOLAAN DANA DESA DI DUSUN SEBERANG JAYA KECAMATAN BATHIN II PELAYANG KABUPATEN BUNGO
Authors: Sunaryo Joko , Dowindra Dowindra , Darmawanto Darmawanto , Handani Deni
Published: October 2022

Penelitian ini dilatarbelakangi oleh ada indikasi terdapat pelaksanaan kegiatan tidak dipasang papan informasi pembangunan dan kegiatan pembangunan yang dilaksanakan oleh pemerintah dusun tidak sesuai dengan Rencana Anggaran Biaya (RAB) atau perencanaan yang telah ditetapkan sebelumnya.Tujuan penelitian ini untuk mengetahui transparansi? pemerintah Dusun Seberang Jaya dalam pengelolaan dana desa. Metode yang digunakan dalam penelitian ini ialah deskriftif kualitatif. Populasi dalam penelitian ini ialah pemerintah Dusun dan BPD Seberang Jaya ?dan tokoh masyarakat. Sampel berjumlah 9 orang yang diambil dengan teknik purposive sampling. Teknik pengumpulan data yaitu observasi, wawancara, dan dokumentasi.Hasil penelitian diketahui bahwa pemerintah Dusun Seberang Jaya dalam pengelolaan dana desa belum mengacu pada prinsip transparansi pengelolaan dana desa. Hal ini terlihat dari belum semua masyarakat mengetahui tentang jadwal penyusunan kegiatan pembangunan dusun dan masih terdapat kegiatan pembangunan dusun tidak dilengkapi dengan papan informasi pembangunan. Selain itu masyarakat masih mengalami kesulitan untuk memperoleh atau mengakses informasi secara siap, mudah dan tepat waktu terkait dengan rencana anggaran kegiatan pembangunan dusun. Pemerintah Dusun Seberang Jaya hanya memberikan informasi jumlah keseluruhan anggaran melalui papan informasi APBDus dan belum dapat memanfaatkan teknologi informasi guna memenuhi semua kebutuhan informasi yang diinginkan masyarakat karena masih mengalami keterbatasan sumber daya manusia dan sarana dan prasarana lainnya.
ANALISIS KEPUASAN KONSUMEN TERHADAP KOPI HALAL NETWORK INTERNATIONAL (HNI) PRODUK PT. HPAI DI WONOGIRI, INDONESIA
Authors: Setiawan Indra , Rahmadieni Risky Yuniar , Rejeki Sari
Published: October 2022

Abstract: Research with quantitative descriptive methods was carried out on Coffe HNI products. The purpose of this study is to determine whether customer satisfaction from Coffe HNI products is influenced by price, product quality, and promotion. Customer satisfaction is important for a business if they don’t want to lose their customers. Coffe HNI is a coffe product that has been established since 2012 in Indonesia. The population in this study is Coffe HNI customer who live and have activities in Wonokarto Kelurahan, Wonogiri. Samples taken as many as 100 respondents using the Random Sampling method through direct distribution to outlets in Wonokarto and through Google Form. Quantitative analysis technique with the analytical toolusedisPartialLeastSquare(PLS).Theresultsshowedthatthepriceandproduct quality variables were influential and significant for customer satisfaction. While promotion variables have no effect and are not significant for customer satisfaction.
Keywords: Customer Satisfaction, Price, Product Quality, Service Quality, Promotion
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KEPATUHAN IBU DALAM PEMBERIAN IMUNISASI DASAR PADA BAYI DI PUSKESMAS KECAMATAN CENGKARENG JAKARTA BARAT
Authors: Desnita  , Yanuar
Published: October 2022

The immunization program has large leverage to improve community health status, because the majority of infant mortality can be prevented by immunization interventions. One effort to improve children's immunity is the giving basic immunization. In immunization programs mother's role is the most important, knowledge of mothers about immunizations influence the implementation immunization itself. To maximize the results of the immunization, it should be given routinely. The purpose of this study was to determine the relationship between the level of knowledge with obedience mother in giving of basic immunization to infants. This research method is descriptive correlation with a quantitative approach. The population in this study were mothers who had babies to immunization in Puskesmas Cengkareng, West Jakarta. The number of samples obtained 50 respondents. Data were  collected by questionnaire. Data analysis using chi-square test with p-value (> 0.05).      The results showed 46 respondents were knowledgeable of both adherent in the giving of basic immunization 43 respondents (93.5%) and less adherent knowledgeable three respondents (6.5%) of 4 respondents. Statistical test results obtained with chi square p-value 0.191 (> 0.05). There is no significant relationship between the level of knowledge of mothers with maternal compliance in the provision of basic immunization in infants. Because, basically, mothers who have very high awareness of immunization.
PENGARUH SENAM KAKI PADA LANSIA PENDERITA DIABETES MELLITUS DI PUSKESMAS DUREN SAWIT
Authors: Desi Purnamasari
Published: October 2022

Physical exercise is very important in controlling diabetes because of its effect on lowering blood glucose levels by increasing glucose uptake by muscles and improving insulin use. The purpose of the study was to determine the effect of foot exercise on the elderly with diabetes mellitus at the Duren Sawit Health Center. The research design used is a quasi-experimental where the subject group is observed before the intervention is carried out, then observed again after the intervention is carried out. From the results of this study, it can be seen that 78.4% of those who follow leg gymnastics are elderly people who are more than 60 years old and 64.9% are women. The statistical test results obtained p-value = 0.000, it can be concluded that there is a significant difference between before and after DM foot exercise on the sensitivity of the feet of elderly people with DM.
GAMBARAN POLA ASUH ORANG TUA TERHADAP PERKEMBANGAN REMAJA DI SMP KRISTEN IMMANUEL GROGOL
Authors: Lyana Arsianti  , Bernadetta Miranti Debora  , Arni Safdiantina
Published: October 2022

Pattern foster parent is all the interactions between parents and children. Interaction herein referred attitudes expression value of attention in the care and training of their behavior. Parenting is a complex issue that includes action, interaction and reaction of all family members are father, mother, and each - each child. This study aims to look at the picture to the parents' parenting adolescent development. This study design using simple descriptive is one type of research methods to see the picture to the parents' parenting adolescent development in accordance with what it is. The number of samples used by 45 respondents in class VII and class VIII SMP Kristen Immanuel. These results indicate that people know students SMP Kristen Immanuel parenting parents apply the most dominant is the democratic parenting parents as much as 34 respondents (75.6%) while the value of being authoritarian parenting as much as 8 respondents (17.8%), and the lowest value of permissive parenting as much as three respondents (6.7%).
HUBUNGAN TINGKAT PENGETAHUAN HIPERTENSI PADA LANSIA DENGAN KEPATUHAN MENGIKUTI TATA PELAKSANAAN HIPERTENSI
Authors: Anitha Anitha
Published: October 2022

Hypertension is a condition where a person's blood pressure is above the optimal normal limit of 120 mmHg for systolic and 80 mmHg for diastolic. This disease can be categorized as a disease because the patient does not know he has hypertension before checking his blood pressure. This study aims to determine the relationship of knowledge level, hypertensive disease in elderly with elderly compliance in following posyandu elderly in Rawa Buaya Cengkareng, West Jakarta. The design of this study is descriptive correlation with cross sectional approach with a large sample of 73 respondents recruited with random sampling. Data collection using instrument in the form of kuesiner. The data analysis is univariate analysis in the form of frequency distribution and bivariate analysis in the form of different test of two proportions (chi-square). Of the 73 respondents the average age of the elderly between 60-74 years is 79.5%, the most sexes are women 67.1%, the most basic educated elderly are 49.3%, the highest level of knowledge of the elderly (high ) was 64.4%, while for a good compliance rate of 49.3%. There is no significant correlation between Knowledge with compliance in following the posyandu of mswarling elderly marsh swamp crocodile cengkarteng west jakarta. (P value = 0.688).
PENGARUH PENDIDIKAN KESEHATAN MELALUI WHATSAPP TERHADAP PENGETAHUAN TENTANG DIET SEHAT PADA PENDERITA DIABETES MELITUS
Authors: Nisi Saharudin , Kamini Kamini , Idham Widya Nugraha
Published: October 2022

This research was carried out in the area of ​​Rawa Buaya Village which is a partner of STIK Kesosi. The population in this study were all diabetics. This study aims to determine the effect of health education through WhatsApp on knowledge about the dietary patterns of people with diabetes mellitus. This study uses an experiment with a quasi-experimental approach with a non-equivalent control group design. The population in this study were all diabetics with a sample of 38 respondents in each group using a simple random sampling technique. The results in this study indicate that between the treatment and control groups the P value of Knowledge Value is 0.002. P Value of Attitude is 0.003. P Value of Diet is 0.001 . Thus, it can be concluded that there is an effect of health education through WhatsApp on the knowledge of the diet of people with diabetes mellitus. Patients' knowledge of DM is a tool that helps patients carry out diabetes management throughout their lives. Thus, the more and better the sufferer understands about his disease, the more he understands how to change his behavior and why it is necessary. So it is recommended that related parties pay more attention to people with diabetes, in providing understanding to sufferers to increase understanding and apply appropriate eating patterns.
Development of Human Resource Management Structural Equation Model of the Automotive Parts Manufacturing Industry in Thailand
Authors: Nanthasudsawaeng Kritchouw
Published: October 2022

This research aims to study the human resource management model influencing the operational efficiency of the automotive parts manufacturing industry in Thailand. It is quantitative research and the research tool used was a questionnaire. The sample groups were executives of 500 establishments. The results showed that the knowledge management was average at a high level followed by human resource management, operational efficiency, and organizational innovation. The correlation analysis found that human resource management had a close relationship with organizational innovation. Knowledge management and operational efficiency were high as per the results of the concordance analysis of the model. It was found that the factors directly influencing operational efficiency were human resource management, organizational innovation, and knowledge management. These factors are important tools that help increase operational efficiency and create sustainable competitive advantages for the automotive parts manufacturing industry in Thailand.
Spontaneous Subarachnoid Haemorrhage After COVID-19 Vaccination; a Rare Case Report
Authors: Abdollahi Mostafa , Alidaei Nasim , Ayar Ayoub
Published: October 2022

Introduction: Cerebrovascular incidents are considered uncommon but important complications of vaccination against coronavirus disease-2019 (COVID-19). Subarachnoid hemorrhages (SAH) usually occur due to an underlying cerebral aneurysm. In this study, we have reported a subarachnoid hemorrhage incidence in a patient shortly after receiving the COVID-19 vaccine (ChAdOx1-AstraZeneca). Case Presentation: A 69-year-old male with no remarkable risk factors referred to the emergency room with complaints of headache, nausea, and vomiting. The patient had received his first dose of vaccine against COVID-19 four days before symptoms started. An aggravated headache, nausea, elevated blood pressure (180/100), and drowsiness occurred on the second day of admission. Imaging implied on acute hydrocephalus and increased intracranial pressure (ICP) caused by subarachnoid hemorrhage. The condition was treated by inserting an external ventricular drain (EVD). We found no underlying vascular abnormality in primary and follow-up cerebral angiographies. Conclusions: Reported cerebral haemorrhages caused by COVID-19 vaccination are mostly intra-parench. Our study observed a type of cerebrovascular event that has not been reported frequently. Vaccine-associated cerebrovascular events, however rarely, are critical. It is important to demonstrate possible risks and complications, as vaccination programs against COVID-19 have become an essential part of health care in most countries.
Investigation of the Relationship Between Emotional Well-being and Coping Behavior in Adolescence
Authors: Tsirul'nikova Elena Aleksandrovna , Shvarts Tat'yana Sergeevna
Published: October 2022

The subject of the study is an empirical analysis of the relationship between the level of emotional well-being and coping behavior of adolescents In the course of the study, a technique for diagnosing stress-coping behavior was used (D. Amirkhan). In order to assess socio-psychological distress and destructive behavior, an express assessment map was developed, including a study of socio-environmental (social distress, social maladjustment, sustained social isolation) and psychological markers (accentuated features of age-related personality development, destructive communication/aggression, psychological maladjustment, autoaggression). Thanks to the correlation analysis carried out according to the r-Spearman criterion, it was possible to establish the essential interrelations of socio-environmental markers of emotional distress of adolescents with coping strategies. As a result of the conducted research, it was found that the reaction of adolescents to socio-environmental distress is associated with the ability to overcome difficult life periods. With the ability of a teenager to independently resolve existing difficulties or turn to social support, it is easier for a teenager to endure external disharmony, which allows him to maintain emotional stability. In conditions when a teenager does not have constructive ways of coping and is not ready to tell others about his experiences, social distress is aggravated by emotional disharmony, which leads to the development of stable social isolation and autoaggression. Also in our article, ways of working with adolescents with different levels of emotional distress were proposed.
The Application of Remote Sensing Techniques and Spectral Analyzes to Assess the Content of Heavy Metals in Soil – A Case Study of Barania Góra Reserve, Poland
Authors: Sobura Szymon , Hejmanowska Beata , Widłak Małgorzata , Muszyńska Joanna
Published: October 2022

The understanding of the spatial and temporal dynamics of farmland processes is essential to ensure the proper crop monitoring and early decision making needed to support efficient resource management in agriculture. By creating appropriate crop management strategies, one can increase harvest efficiency while reducing costs, waste, chemical spraying, and inhibiting the impact of biotic and abiotic factors on crop stress. Only reliable spatial information makes it possible to comprehend the influence of various factors on the environment. The main objective of the research presented in the paper was to assess the possibility of using maps of vegetation and soil indices, such as NDVI, SAVI, IRECI, CIred-edge, PSRI and HMSSI, calculated on the basis of images from the Sentinel-2 satellite, to qualitatively determine the increased amount of heavy metals in the soil in the areas of small agricultural plots around the Barania Góra nature reserve in Poland.The conducted pilot project shows that the spectral indices: NDVI, SAVI, IRECI, CIred-edge, PSRI, and HMSSI, calculated on the basis of images from Sentinel-2, have the potential to assess the content of nickel zinc, chromium and cobalt in the soil on agricultural plots. However, the confirmation of the obtained results requires continuation of the research.
Nitrogen fertilization and CO2 concentration synergistically affect the growth and protein content of Agropyron mongolicum
Authors: Xu Aiyun , Zhang Lihua , Wang Xiaojia , Cao Bing
Published: October 2022

Background

The nitrogen (N) and protein concentrations in plant tissues exposed to elevated CO2 (eCO2) generally decline , such declines in forage grass composition are expected to have negative implications for the nutritional and economic value of grass. Plants require N for the production of a photosynthetically active canopy and storage proteins in the tissues, whose functionality will strongly influence productivity and quality. The objective of this study was to investigate whether eCO2 plus N-fertilization increases growth and N nutrition of Agropyron mongolicum, and the dependence of this improvement on the coordination between root and leaf development.

Methods

We analyzed A. mongolicum from field-grown within the open-top chambers (OTCs) facility under two atmospheric CO2 (ambient, 400 ± 20 µmol mol−1, aCO2, and elevated, 800 ± 20 µmol mol−1, eCO2) and three N-fertigation treatments (control, low N-fertigation , and high N-fertigation) for two months.

Results

Elevated CO2 plus N-fertigation strongly increased shoot and root biomass, and the nitrogen and protein concentrations of A. mongolicum compared to those plants at aCO2 levels. Increased N content in leaves and reduced specific leaf area (SLA) at a high N supply could alleviate photosynthetic acclimation to eCO2 and drive the production of greater shoot biomass with the potential for higher photosynthesis, productivity, and nutritional quality. The increased root length (RL), the ratio of total aboveground N taken up per RL (TN/RL), stomatal conductance (Gs), and transpiration rate (Tr) contribute to the transpiration-driven mass flow of N, consequently increasing N uptake by roots. In addition, a smaller percentage of N remained as unassimilated nitrate (${\mathrm{NO}}_{3}^{-}$) under eCO2, indicating that assimilation of ${\mathrm{NO}}_{3}^{-}$ into proteins was not inhibited by eCO2. These findings imply that grass productivity and quality will enhance under anticipated elevated CO2 concentration when effective management measures of N-fertilization are employed.
SES1 is vital for seedling establishment and post-germination growth under high-potassium stress conditions in Arabidopsis thaliana
Authors: Guan Peiyan , Xie Chen , Zhao Dongbo , Wang Liyan , Zheng Chengchao
Published: October 2022

Background

The potassium ion (K+) plays an important role in maintaining plant growth and development, while excess potassium in the soil can cause stress to plants. The understanding of the molecular mechanism of plant’s response to high KCl stress is still limited.

Methods

At the seed stage, wild type (WT) and SENSITIVE TO SALT1 (SES1) mutants were exposed to different concentrations of potassium treatments. Tolerance was assayed as we compared their performances under stress using seedling establishment rate and root length. Na+content, K+content, and K+/Na+ ratio were determined using a flame atomic absorption spectrometer. In addition, the expressions of KCl-responding genes and ER stress-related genes were also detected and analyzed using qRT-PCR.

Results

SES1 mutants exhibited seedling establishment defects under high potassium concentration conditions and exogenous calcium partially restored the hypersensitivity phenotype of ses1 mutants. The expression of some K+ transporter/channel genes were higher in ses1-2, and the ratio of potassium to sodium (K+/Na+) in ses1-2 roots decreased after KCl treatment compared with WT. Further analysis showed that the ER stress marker genes were dramatically induced by high K+ treatment and much higher expression levels were detected in ses1-2, indicating ses1-2 suffers a more serious ER stress than WT, and ER stress may influence the seedling establishment of ses1-2 under high KCl conditions.

Conclusion

These results strongly indicate that SES1 is a potassium tolerance relevant molecule that may be related to maintaining the seedling K+/Na+ balance under high potassium conditions during seedling establishment and post-germination growth. Our results will provide a basis for further studies on the biological roles of SES1 in modulating potassium uptake, transport, and adaptation to stress conditions.
A Python script to design primers for overlap extension PCR to ligate two DNA fragments
Authors: Hu Yunzhuo , Xu Fei , Huang Bifang , Chen Xuanyang , Lin Shiqiang
Published: October 2022

Ligating two or more DNA fragments is a regular operation for the subcloning and the engineering of vectors. The overlap extension PCR serves as a straightforward method to solve this issue. However, it takes a relatively long time to design the appropriate overlapping primers and the primers for the full-length sequence, and there has not been a professional offline software for such kind of primer design. Here, we propose a Python script to search, calculate and sort thousands of combinations of primers for users according to the predefined parameters. The results of script running and experimental validation show that this script is capable of generating the optimal pairs of primers based on the proper melting temperatures and lengths of the primers, which facilitates gene modification in research.
Functional Role of Pulvinar In the Sustained Attention
Authors: Jiang Xiaoshu , Fang Qi
Published: October 2022

Sustained attention is important for survival in a challenging environment. Oscillatory activities in the pulvinar have been reported to correlate with sustained attention. However, whether pulvinar can causally establish and maintain sustained attention is elusive. To address this question, in this study, we opto-genetically activated pulvinar neurons during delay period in the five-choice serial reaction time task and measured the behavioral outputs. We found that pulvinar firing rates were significantly increased after optogenetic stimulation. Also, in the behavioral test, the correct rates were remarkably increased with decreased omission rates, but the reaction time and reward retrieval time remained the same. Together, these results deepen our understanding of the functional role of pulvinar in sustained attention.
Vers un partenariat pour la création de milieux scolaires favorisant, durablement et de façon efficiente, la socialisation et le bien-être psychologique des élèves et du personnel
Authors: Bowen François , Morissette Éric , Levasseur Caroline , Marion Élodie , Carpentier Geneviève , Poirel Emmanuel , Beaumont Claire , Leadbeater Bonnie , Beaulieu Judith , Ouellet-Morin Isabelle , St-Cyr Claude , Cantin Stéphane , Fullan Michael
Published: October 2022

Cet article décrit un projet de recherche collaborative, entre praticiens-partenaires et chercheurs, portant sur un modèle d’accompagnement et de formation des intervenants scolaires, visant une mise en oeuvre optimale et durable de programmes et d’interventions fondées sur des données probantes concernant le développement de la socialisation des élèves (prévention de la violence) ainsi que leur bien-être psychologique. La conceptualisation et l’expérimentation de ce modèle reposeront sur une structure et un fonctionnement partenarial mobilisant pas moins de 11 organisations représentant divers partenaires du milieu scolaire, qui travailleront avec plus de 18 chercheurs et 10 collaborateurs sur une période de trois ans.
Antioxidant and Antibacterial Activity of Caulerpa Flour (Caulerpa lentifera) as Functional Food Raw Material
Authors: Arfini Fifi , Mahendradatta Meta , Metusalach . , Zainal . , Malle Sriwatti
Published: October 2022

Aims: This research aims to study the process of making Caulerpa seaweed flour and extract; analyzed the antioxidant activity and inhibitory antibacterial activity of Caulerpa flour.

Study Design: The experimental design used in the first stage is the T-test by comparing the two washing treatments (3 times and 5 times), and in the second stage using a Completely Randomized Design.

Place and Duration of Study: The present study was conducted in Department of Aquatic Product Processing and Storage, Pangkep State Polytechnic of Agriculture. The duration of research is 6 month i.e from April, 2022 – September, 2022.

Methodology: The drying method is carried out by weighing fresh Caulerpa lentifera. samples and spread them on a baking sheet and in an oven to dry at 50°C. Caulerpa lentifera, which has been in powder form, will be analyzed for its antioxidant and antimicrobial properties. The extraction process will also be carried out on Caulerpa lentifera flour and analyzed for its antioxidant and antimicrobial properties.

Results: The results of the first phase of the study showed that the 5 times washing process on Caulerpa seaweed resulted in better quality than 3 times washing with an antioxidant value of 115.36 ppm, the water content of 9.9%; ash content of 23.65%; Ca levels of 152.4 mg/100 g; fiber 41.24%; Iodine 31.08 g/g and 4.16% yield. Caulerpa flour had the highest antioxidant and antibacterial activity compared to ethyl acetate and methanol with a value of 115.36 mg/L and an inhibitory diameter of 6.88 mm against Escherichia coli.

Conclusion: The antioxidant activity of seaweed flour is in the medium category and has an inhibitory power against pathogenic bacteria E.coli, so it has the potential as a functional food.
Screening of Hybrid Varieties of Tomato Crop against American Serpentine Leaf Miner, (Liriomyza trifolii, Burgess) in Lucknow District of Uttar Pradesh, India
Authors: Rai Deepak , Dubey A. K. , Singh S. N.
Published: October 2022

Tomato is a major cash crop of farmers of central plain of Uttar Pradesh. Injudicious use of chemicals invited too many number of insect pests. Among them sucking insect problems were very serious in comparison to biting and chewing insects because these insects developed resistance and insecticides. So, in last five years pest scenario had changed. Some new insects were seen on crops. In which, American serpentine leaf minor in one of them. Their incidence increasing very rapidly in different crops like tomato, vegetable pea and cucurbitaceous crops etc. Tomato crop was more susceptible for leaf miner. Due to which screening of popular tomato varieties were urgently needed. On that basis this study were carried out on ten popular hybrid varieties. The field incidence of the serpentine leaf miner, L. trifolii (Burgess) was severe during the fruiting stage of the crop. Infestation was higher on lower surface of leaf in comparisons of upper surface. On the basis of cumulative susceptibility index test varieties all varieties viz. Pusa Rohini, Pusa Uphar, Arka Saurabh, Naveen-2000, N-815, Arka Vardan, Pusa Sadabahar, Arka Vishal, N-2535 and ArkaVardan were found to be resistant/less susceptible. There were no significant correlation found among leaf miner incidence and yield of crop. All tested hybrid varieties performed better in Lucknow district of Uttar Pradesh.
The Impact of Perceived Service Quality on Customer Loyalty towards Chinese Fitness Centres: The Moderating Role of Reputation/Image
Authors: Gu Shengyu
Published: October 2022

The trend of joining a fitness club has been growing rapidly since the last decade, but it's difficult to justify the actual reason which can keep the members of the club loyal. This study has indicated some key reasons for customer loyalty, including perceived service quality and customer satisfaction which is influenced by customer delight. Therefore, the basic aim of this research is to explore the effect of perceived service quality on customer loyalty. To explore the relationships made by deep literature analysis, this research collected data from 411 members of Chinese fitness clubs. This data was further observed in AMOS software to ensure the results of the hypothesis. The results highlighted that there is a significant and positive impact of perceived service quality on customer delight and customer loyalty. The delighted customer will be satisfied and that satisfaction will lead to customer loyalty. In addition, reputation and image can significantly moderate the relationship between customer satisfaction and customer loyalty. The managers of owners of fitness clubs can seek the important results highlighted by this research for developing marketing strategies for clubs.
Changes in Liver Histomorphology, Hematological Parameters and Lipid Profile of Cadmium-Exposed Rats Treated with Combined Leaf Extract of Vernonia amygdalina and Occimum gratissimum
Authors: Orororo Osuvwe Clement , Efekemo Oghenekevwe , Udi Onoriode Andrew
Published: October 2022

Aim: This study was aimed at examing the effect of mixture of Ocimum gratissimum extract and Vernonia amygdalina extract on lipid profile and hematological parameters of Wistar rats administered with cadmium.

Methodology: Sixteen female rats were divided into four groups and designated as follows: Group 1-Control (Normal Saline,) Group 2-(Cadmium 10mg/kg bwt), Group 3 (Normal saline, leaf extract 200kg/kg bwt) Group 4 (Cadmium 10mg/kg bwt and leaf extract 200kg/kg bwt) and were treated for 28 days (4 weeks).

Results: Exposure of rats to Cadmium alone (Group B) brought about significant increase in levels of Cholesterol, TAG and LDL with a decrease in HDL compared to control and rats maintained on plant extract alone (Group 3). However, treatment of Cd-exposed rats with mixture of the plant extracts (Group 4) significantly reduced Cholesterol, TAG and LDL with an increase in HDL compared to rats maintained on Cd alone (Group 2). The PCV and RBC of the rats administered with the cadmium showed a significant reduction when compared to the control group, whereas the WBC increased significantly (p< 0.05). The group administered with the leaf extract and a combination of the leaf extract and cadmium recorded an increased in the (PCV), (RBC) level of the Wistar rat and a reduction in the (WBC) level when compared to the group administered with cadmium.

Conclusion: The findings of this study demonstrate that mixture of Ocimum gratissimum and Vernonia amygdalina extracts have lipid lowering properties that may be advantageous to those with the problem of cadmium toxicity. The extracts were also found to be efficient in decreasing cholesterol, triacylglyceride, and low density lipoprotein levels, indicating that they have hypocholesterolaemic properties.
Study on the Hypolipidemic Effect of Moringa oleifera Seeds Based on Zebrafish Hyperlipidemia Model
Authors: Yuan Tao , Wen Xin-Yu , Chen Yue , Deng Yan , Li Hong-Zhi , Huang Yi
Published: October 2022

Objective: Investigated the hypolipidemic effect of alcoholic extract of Moringa oleifera seeds using the zebrafish hyperlipidemia model.

Methods: Using 0.3% egg yolk solution to feed zebrafish larval to construct the hyperlipidemia model. These larval fish in the model were treated with an extract of Moringa oleifera seeds for 2 days. Then, the tail vessels were observed after oil red O staining, and the accumulated optical density of lipids was analyzed. The body length, triglyceride (TG), and cholesterol (TC) levels were measured. Result: The accumulated optical density of lipids in the tail vessels of larval fish fed with 0.3% egg yolk was significantly higher than that of the blank group. The contents of TG and TC were also increased, indicating that the hyperlipidemia model was successfully established. After treatment with different concentrations of Moringa oleifera seed extract (10 μg/ml, 15 μg/ml, and 20 μg/ml), the staining attachment surface of vascular oil red O in the tail of hyperlipidemic zebrafish was significantly reduced by 42.8%, 63.3%, and 80.6% respectively. TG was reduced by 9.89%, 20.41%, and 26.40%. TC was reduced by 9.85%, 23.93%, and 33.80%. The data of each group were statistically significant (P<0.01).

Conclusion: Moringa seeds had a significant hypolipidemic effect on zebrafish and had no significant effect on the skeletal growth length of zebrafish.
Establishing Equivariant Class [O] for Hyperbolic Groups
Authors: Bhattacharjee Deep
Published: October 2022

This paper aims to create a class [O] concerning the groups associated with Gromov hyperbolic groups over correspondence and equivalence through Fuchsian, Kleinian, and Schottky when subject to Laplace – Beltrami in the Teichmüller space where for the hyperbolic 3-manifold when the fundamental groups of Dehn extended to Gromov – any occurrence of Švarc-Milnor lemma satisfies the same class [O] for quotient space and Jørgensen inequality. Thus the relation (and class) extended to Mostow – Prasad Rigidity Theorem in a finite degree isometry concerning the  structure of the commensurator in higher order generalizations suffice through CAT(k) space. The map of the established class [O] is shown at the end of the paper.
A Chaotic Clifford Attacker Map-based Image Encryption in Double Random Phase Encoding
Authors: Kalra Sahil , Siwach Vikash , Redhu Poonam , Vandna .
Published: October 2022

Encryption is the most useful technique used for the security of data during storage and transmission. A well-known encryption scheme called Double Random Phase encoding was introduced by Refregier and Javidi. But due to its linear nature, this scheme has been proven vulnerable against Known plaintext and chosen plaintext attacks. Here in this paper, we propose a chaotic map-based nonlinear encryption scheme that enhances the security of the DRPE encryption scheme for images. Clifford attacker is a non-linear chaotic map that has four parameters and two initial values. This map is highly sensitive to these values. Therefore, these parameters and initial values work as extra secret keys. MATLAB simulation shows that the proposed technique enhances the security level of the DRPE and at the same time has a better immunity to noise and occlusion attacks.
CD8+ Mycosis Fungoides in Peripheral Blood; A Rare Finding
Authors: Meraj Fatima , Khan Hamza , Zaman Amna Qamar uz , Jamal Saba
Published: October 2022

Cutaneous T cell lymphomas are mature lymphomas of T lymphocyte presenting with skin lesions and/or systemic manifestations. Majority of these cases show CD4+ phenotype and are classified as Mycosis Fungoides (MF)/Sezary syndrome (SS) spectrum.

Here we present a case of 74-year-old male patient, having no known comorbid, presented in Dr. Ziauddin Hospital, Karachi OPD with complains of generalized skin lesions, itching for 2 years, generalized weakness for 4 months and no lymphadenopathy or visceromegaly. CBC showed absolute lymphocytosis and absolute eosinophilia. Some lymphocytes exhibited cerebriform nuclei. CT scan neck, chest and abdomen showed bilateral enlarged superficial inguinal lymph nodes and multiple enlarged bilateral axillary lymph nodes. Skin biopsy was inconclusive. Immunophenotyping of peripheral blood was then performed which showed an aberrant T cell population showing positivity for CD3, CD8, CD2, CD25 and negative for CD4, CD45, CD5, CD30, CD56 with variable expression of CD7. Case was finalized as CD8+ Mycosis Fungoides with peripheral blood involvement.

These findings are very rare and highlight the importance of integrated approach to clinical course, morphological findings and other ancillary tests to be used in correlation with each other. These findings also highlight the diversity present in T cell malignancies in terms of immunophenotype.
Who is Responsible for Climate Change: Celestial Phenomena or Human Activity?
Authors: Silva Carlos Augusto Ramos e
Published: October 2022

One of the great contemporary concerns of humanity is the analysis of climate change, that is, of the processes that alter the structure and functioning of the planet as a system and whose causes are inherently related to human activities. The direct relationship between climate change and carbon cycling in ecosystems is increasingly debated. Arrhenius in 1896 may have "planted the seed" of "global warming" when he launched the theory of the "greenhouse" in the planet's atmosphere by CO2 [1]. Several premises are assumed as evidence of global warming, such as: records in the ice core and records of the concentration of carbon dioxide in the atmosphere in the 19th and 20th centuries. It has never been experimentally demonstrated that records in ice cores are reliable in representing the original atmospheric composition. And the objections in the records of [CO2] in the atmosphere by renowned scientists have never been considered by climatologists.
Customized Fertilizer: A Key for Enhanced Crop Production
Authors: Bhadu Anil , Singh Bhim , Gulshan Tajalee , Kumawat Shesh Narayan , Choudhary Rakesh Kumar , Farooq Faraaz
Published: October 2022

One of the most important inputs in increasing food grain production is fertiliser. In terms of nutrients (N, P, and K), annual fertiliser consumption has increased from 0.07 million tonnes in 1951–1952 to more than 26.5 million tonnes in 2017–2018 [1], and consumption per hectare has increased from less than one kilogramme in 1951–1952 to the level of 137.62 kilogrammes in 2015–16. An important component for crop yield and productivity is fertiliser. Fertiliser use accounts for 55% of increased food output. India's annual food grain requirement is around 300 mt per annum by 2020. The area under cultivation cannot be expected to grow beyond the current 142 mha, hence a large portion of the increase in food grain output must be achieved by increasing productivity per unit area. In comparison to most crops, rice has a nitrogen fertiliser efficiency of just 30–40% and other cereals have a phosphorus fertiliser efficiency of 15–20%. Combinations of primary nutrients, secondary nutrients, and micronutrients may be included in the customised fertiliser. At customised fertilisers, major ingredients like Urea, Diammonium Phosphate (DAP), and Potash are combined with micronutrients like sulphur, zinc, and boron in a ratio that is appropriate for certain crops and soil types. As we know that, in addition to bigger amounts of fertilizer being removed, the development of high yielding systems is likely to make the problem of secondary and micronutrient deficiencies worse by applying huge amounts of N, P, and K to meet higher yield targets. As a result, there is a chance that in intensive systems, a negative balance may develop and there will be a shortage of secondary and micronutrients. Balanced fertilisation, site-specific nutrient management, and customised fertilisers will all be crucial in achieving sustainable future goals. In long run, such a strategy may also increase agricultural yields and prevent the loss of soil fertility. As a result, the current article concentrates on the various features of customised fertilisers connected to their necessity, production, standards, and long-term prospects.
Various Methods Involved in Studying Persistence and Residues of Pesticides in Soil
Authors: Naik D. Balaji , Gurumurthy K. T.
Published: October 2022

Pesticides protect plants or plant products from crop pests, plagues, and weed competition, improving yields and protecting the assembly's availability, quality, dependability, and economic competitiveness for the benefit of farmers and consumers. The introduction of cutting-edge technologies, from breeding to harvesting, has contributed to an increase in agricultural yields. These activities are aided by the use of agrochemicals, which in general endanger the environment's sustainability by polluting soils, water, and air. Pesticides' harmful effects pose a threat not only to nearby natural habitats, but also to cropland itself.
Nutrient Transformation in Different Land Use Systems
Authors: Naik D. Balaji , Gurumurthy K. T.
Published: October 2022

Land use is an emerging socio-economic activity wherein a region of one major specific purpose utility may be converted into another land for general purpose utility. Land use and management practices influence soil nutrients related to soil processes, such as erosion, oxidation, mineralization and leaching, consequently modifying the transport and redistribution processes. Deforestation is widespread in the tropics, and future changes in land use may have an impact on soil nutrient conversions. Understanding how the ecosystem operates and estimating the effects of future land use change on soil properties require characterising the spatial variability of soil nutrients in relation to site properties such as climate, land use, topography, and other variables.
Screening and Characterization of L-asparaginase Producing Bacterial Strains from the Soil in Bangladesh
Authors: Kabir Md. Mohiuddin , Imam Md. Rayhan , Nijhum Tasrin Naher , Hossain Chowdhury Faiz
Published: October 2022

Although the enzyme L-asparaginase (L-ASNase) from Escherichia coli, Erwinia and Serratia has been applied to treat certain lymphomas and leukemias, several medical complications such as severe immunological responses leading to hypersensitivity, anaphylaxis, etc. have limited its application. The researchers have documented that such impediments are due to the different biochemical and kinetic properties of L-ASNase, which are directly dependent on genetic variations in microbial strains. Thus, there is a compelling need to explore novel L-ASNase producing microorganisms that would exhibit different serological properties while retaining similar and/or better therapeutic effects against cancer cells. Heretofore, L-ASNase producing bacterial strains from Bangladesh have never been isolated and characterized. Therefore, the main objective of this research was to isolate and characterize these strains from unexplored and ecologically different habitats that could lead to developing a potential therapeutic drug with fewer immunological responses and side effects over the existing drugs in order to treat cancer patients in the near future. Two L-ASNase producing bacterial strains were successfully isolated from the soil of Hatirjheel lake in Dhaka for the first time. Molecular characterization revealed that both strains belonged to Pseudomonas aeruginosa and their DNA sequences were submitted to NCBI GenBank. The accession number OK446669 was obtained for the strain of P. aeruginosa EWUKR-1 and OL307081 for P. aeruginosa EWUKR-2. The specific activity of L-ASNase from EWUKR-2 (212.1 ± 14.8 U/mg protein) was significantly higher than that of EWUKR-1 (16.3 ± 0.8 U/mg protein) when they were grown in modified M9 media containing 0.5 g/l glucose at 370C for 24 hours. The experimental results revealed that both of these bacterial strains were extracellular L-ASNase producers. The enzyme from P. aeruginosa EWUKR-2 was partially purified using saturated ammonium sulfate followed by dialysis and concentrated using Vivaspin-20 centrifugal concentrator having MWCO of 30 kDa. The optimum temperature and pH of the partially purified enzyme were 370C and 7.5, respectively. The purification-fold after ammonium sulfate precipitation and yield of the concentrated enzyme were 2.8 and 101%, respectively. SDS-PAGE analysis revealed that the molecular weight of L-ASNase from P. aeruginosa EWUKR-2 was around 43 kDa.
An Unusual Detected Cause of Abnormal Liver Enzymes in an Aircrew Member Periodical Visit: Case Report
Authors: Zerrik Meryem , Echchachoui Houda , Iloughmane Zakaria , Ghazi Mouna El , Smires Fahd Bennani , Khalifa Mohamed El , El’mhadi Choukri , Benaissa Laila , Chemsi Mohamed
Published: October 2022

Background: Hepatic tuberculosis (TB) is a rare entity, poorly described in the literature. It presents with nonspecific clinical manifestation and imaging findings mimicking other liver disease making diagnosis challenge. We report a case of isolated hepatic tuberculosis in asymptomatic cabin crew member diagnosed accidentally by investigating a liver chemistry test disorder.

Case Report: A 28 year-old Moroccan cabin crew attendant came to the aeromedical expertise center to perform her periodical medical assessment. She had no medical history. Physical examination was unremarkable. Liver chemistry test values were elevated. Imaging studies of the liver suggested malignant disease. Histological examination showed isolated hepatic tuberculosis.

Discussion: Isolated hepatic TB is very uncommon, lacks typical clinical manifestation and radiological features, but remains an important differential diagnosis of hepatic nodules especially in endemic areas. This observation highlights the benefit of liver chemistry test evaluation realized systematically for periodical aeromedical fitness to diagnose some pathology in asymptomatic stage avoiding complications. Hepatic TB is a cause of temporarily unfitness because it’s not compatible with flight safety conditions. Aircrew with hepatic TB will need to be assessed for both complete disease control and full resolution of any iatrogenic side effect of anti-tubercular drugs before returning to fly under some restrictions.
Insecurity and Performance of Business Activities in Anambra State, Nigeria
Authors: Uzoamaka Ndubuisi-Okolo Purity , Francisca Onuzulike Nkechi
Published: October 2022

Insecurity constitutes nuisance to human lives and properties, impedes business activities, inculcate phobia in both local and foreign investors. Consequent upon this, human security has been encroached due to incessant insecurity menace besetting the peaceful co-existence of individuals residing within and outside the vicinity of Anambra State, Nigeria. This scenario has consistently created vacuum for chaos and disorderliness. In the light of the above, this paper focuses attention on insecurity and performance of business activities in Anambra State, Nigeria. Specifically, the study sought to ascertain the factors militating against the successful operation of business activities in Anambra State, and also to determine the type of relationship that exists between the independent variable (human security) and dependent variable (market share). The study adopted both qualitative and quantitative research design method (triangulation) with sixty eight participants randomly selected. The participants comprised of experienced entrepreneurs from Onitsha, Nnewi and Awka with not less than ten years of experience in their diverse businesses. Structured questionnaire and in-depth interview were simultaneously utilized to elicit reliable, timely and valuable information from the respondents respectively. The structured questionnaire was administered to sixty two (62) respondents while six respondents were orally interviewed. Data generated from structured questionnaire was analyzed using Pearson Product Moment Correlation Coefficient which is an inferential statistical tool while data elicited from in-depth interview was thematically analyzed. The results revealed that human security had a statistically positive significant relationship with market share. This implies that a proportionate increase in human security will attract commensurate increase in market share and vice versa. The in-depth interview conducted disclosed that family responsibilities, difficulties in raising children, sit-at-home syndrome, insecurity, high cost of goods, low turnover, forced migration, and insufficient capital are the major factors besetting the performance of business activities in Anambra State, Nigeria. In view of the findings above, we recommended serious government intervention to cushion the effect of human insecurity by adopting a regulatory framework that will usher defaulters to befitting penalty in order to inculcate sustainable virtues in them. That is why, unequivocally speaking, protection of human rights, dignity, and integrity need to be the greatest concern of government at all levels because life has no duplicate. Also, government at all levels need to pay close attention to sit-at-home syndrome and high cost of goods in the market as majority of the entrepreneurs in Awka, Onitsha and Nnewi respectively lean on daily income for the provision of  basic necessities of life.