bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Pluri-Lateral Free Trade Agreements on Innovation: Example of ASEAN
Authors: Smith Robert , Smith Nucharee , Perry Mark
Published: September 2023

Innovation has been identified as a critical indicator for an economy to succeed in the fourth industrial revolution. Historically, some members of the Association of Southeast Asian Nations have been better known for violation of intellectual rights rather than their protection. However, this is changing as their economies develop and they have been better integrated into the global economy. Integration has been facilitated by their membership of the World Trade Organization and bilateral Free Trade Agreements (FTAs) between individual states and their trading parties. ASEAN has entered into plurilateral FTAs with some of its trade partners. A key element of these plurilateral FTAs is that most dedicate a Chapter on the protection of intellectual property rights. These clauses have two essential elements. Firstly, they set out the obligations of the parties to protect intellectual property rights and their commitment to seek membership of intellectual property treaties. Secondly, the parties undertake to assist the lesser developed members with improving their processes and procedures so that they can accede to appropriate treaties. The research analysed the impact of these multilateral FTAs on the protection of patents and marks by the individual ASEAN members.
Family Business Dynamics in Southeast Asia: A Comparative Study of Indonesia, Malaysia, Singapore, and Thailand
Authors: Sukamdani Nugroho
Published: September 2023

The research discussed the literature on family business in four Southeast Asian countries, namely Indonesia, Malaysia, Singapore, and Thailand. The four countries were selected as case studies to contextualize the southeast Asian family business context. In addition, the research perceived that the four countries have similar sociocultural characteristics, potentially providing similar attributes to how family businesses establish and grow. Drawing from literature collected from the Scopus database through the keywords “family business,” “Indonesia,” “Malaysia,” “Thailand,” and “Singapore,” the research provided the dynamics of knowledge production through systemic literature review. A narrative literature review was implemented to provide a high level of abstraction to the literature on family business differences and similarities. The findings show that the theme of succession was widely discussed in the literature. Succession in all four countries still prioritizes members of the family as successors. However, literature in Indonesia provides a more in-depth understanding of the way succession works. The research enriches the present discussion and provides insights for researchers on the research gap in family business issues. At a practical level, the research provides insight for professionals who work in the sector to gain insight into how family businesses work to maintain their entrepreneurial spirit.
A EDUCAÇÃO SUPERIOR NA CONJUNTURA DE FRAGILIZAÇÃO DA DEMOCRACIA NO BRASIL: IMPACTOS SOBRE AS CONDIÇÕES DA OFERTA E DO FINANCIAMENTO
Authors: Moreira Claudia Regina Baukat Silveira
Published: September 2023

Analisa-se os impactos da conjuntura política sobre as condições da oferta e do financiamento da educação superior. Para tanto, recorreu-se a dados de execução do orçamento federal e dados da Receita Federal; recorreu-se, também, aos dados do Censo da Educação Superior. Há um processo de redução do montante direto investido em educação superior, efeito esperado das políticas de austeridade fiscal em vigência, e o privilegiamento do investimento indireto no setor privado, via renúncia fiscal. É fortalecida a oferta privada, com a progressiva ampliação da EaD e a concentração de capital em grupos consolidadores. Tal quadro compromete a compreensão da educação enquanto direito em favor de uma concepção mercadológica.
ADSORÇÃO DE AZUL DE METILENO UTILIZANDO CARVÃO ATIVADO PREPARADO A PARTIR DA CASCA DO TAMBORIL (Enterolobium contortisiliquum)
Authors: Silva Francisco , Cantanhede Leonardo , Marques Izaías , de Figueredo Gilvan
Published: September 2023

ADSORPTION OF METHYLENE BLUE USING ACTIVATED CHARCOAL PREPARED FROM THE PEELS OF MONKFISH (Enterolobium contortisiliquum). Contamination of natural resources by dyes present in industrial effluents causes serious impacts to the environment. Research on efficient methods to remove these contaminants has intensified in recent years. A promising method is adsorption, as it uses effective and low-cost adsorbents, such as biomass. In this study, the adsorptive capacity of carbon chemically activated with phosphoric acid (H3PO4) obtained from monkfish (Enterolobium contortisiliquum) shells was investigated for the removal of methylene blue (MB) dye in aqueous medium. UV-Visible was used to quantify the dye removed from the experimental batch method. Adsorption tests at different temperatures suggest that the Langmuir isotherm model (R2 = 0.9967) and the pseudosecond order kinetic model better fit the experimental data. The negative values of ∆Hads and ∆Gads express that the adsorption dynamics is exothermic and spontaneous. The positive value of ∆Sads suggests an increase in disorder at the solid-solution interface during the process. Under these conditions, TCA (monkfish activated charcoal) presented a qe of 525.15 mg g-1, reaching a removal percentage of 82.67%. The treatment carried out to obtain activated carbon allowed the SEM, BET and FT-IR analyses to reveal a porous surface with the presence of micro and mesopores and acid groups on the TCA surface.
PRECIOS Y COSTO DE OPORTUNIDAD DE LA AGRICULTURA COMERCIAL EN EL PERÚ 2001-2021
Authors: Magallanes Díaz Juan F. , Camasi Montes Carlos F. , Rojas Cubas Juan C.
Published: September 2023

En Perú las exportaciones de origen agropecuario se han multiplicado casi 10 veces, pasando de un valor FOB cercano a los US$200 millones en el 2001, a un valor de US$1 950 millones en el 2022, sin embargo, la participación de sus valores negociables (acciones de empresa) en un mercado centralizado en la Bolsa de Valores de Lima (BVL) es muy reducida. Con excepción de las empresas del azúcar, la mayoría no reportan información sobre los precios de mercado de sus acciones corporativas en la BVL, limitando el cálculo del costo de oportunidad del capital (COK) en este sector. La investigación planteó como objetivo aproximar el COK agrícola a partir de los precios registrados por los productos exportados e importados, considerando una muestra conformada por siete productos de exportación y seis productos de importación, que representan más del 85% del valor de comercialización agropecuaria del Perú con el exterior. Para determinar el COK agrícola se utilizó el modelo Capital Asset Pricing Model (CAPM), un modelo de valoración de activos de capital que permite calcular el precio y comportamiento de los activos financieros variables. La investigación logró el objetivo de determinar el COK para el sector agropecuario comercial en el Perú para el periodo analizado 2001 - 2021, el valor resultante alcanzó el nivel de 20.24%, lo que refleja asumir el riesgo de inversión en este sector y que se encuentra por debajo del cálculos realizados por otros estudios y por debajo de las altas tasas de descuento que la banca comercial aplica al flujo de proyectos de inversión en la agricultura, castigando mucho más el valor de las inversiones en el sector.
PROGRAMA INSTITUCIONAL DE BOLSAS DE INICIAÇÃO EM DESENVOLVIMENTO TECNOLÓGICO E INOVAÇÃO (PIBITI) DA UNIVERSIDADE ESTADUAL DE MATO GROSSO DO SUL - UEMS COMO POTENCIAL FONTE DE INOVAÇÃO FRUGAL
Authors: Ferreira da Silva Luciana , Paim Berti Alessandra , Dos Santos Barros Fabio , Peixoto Rosário Francisco José , Alves de Lima Araken
Published: September 2023

Apesar da questão da frugalidade estar presente no discurso acadêmico por mais tempo, o termo “inovação frugal” tem sido utilizado com maior frequência na última década. Conhecer as iniciativas é fundamental para amadurecer a visão de oportunidades, processos indutores e preparar o ecossistema de inovação para reconhecer as particularidades e desenvolver inovações frugais no Brasil. Conhecer o que tem sido desenvolvido pelas universidades torna-se preponderante nesse processo, e nessa perspectiva, este artigo tem como objetivo analisar o potencial dos projetos desenvolvidos pelo Programa Institucional de Bolsas de Iniciação em Desenvolvimento Tecnológico e Inovação (PIBITI) da Universidade Estadual de Mato Grosso do Sul (UEMS), na geração de soluções tecnológicas locais com características de inovação frugal no período de 2013 a 2021. O desenho metodológico utilizou-se de uma abordagem baseada em técnicas de lexicometria e text data mining a fim de compreender se os projetos PIBITI da UEMS possuem potencial para a construção de interações entre a universidade, empresas ou demandas específicas da sociedade sul-mato-grossense. Evidencia-se claramente a vocação da UEMS nas pesquisas relacionadas às tecnologias agropecuárias, soluções em saúde e educação, desenvolvimento de novos materiais, alicerçadas na expertise instalada nos Centros de Pesquisa e com foco nas temáticas regionais. Foi verificado o viés de inovação frugal nos projetos analisados, o que demonstra a relevância da continuidade, bem como, o aprimoramento do Programa PIBITI, como fonte colaborativa nas soluções tecnológicas locais de Mato Grosso do Sul, potencial fortalecimento da ciência e aplicabilidade na sociedade em geral e empresas brasileiras.
INTELIGÊNCIA ARTIFICIAL
Authors: Vicente Nunes de Oliveira Bruno , Melo Filipe Torres de
Published: September 2023

A Inteligência Artificial – IA pode ser definida como o estudo de agentes computacionais inteligentes que recebem percepções do ambiente e executam ações, bem como tomam decisões autônomas. Na contemporaneidade, esse mecanismo é aplicado em diversos segmentos, desde o agronegócio até os serviços relacionados à saúde. Ademais, em consonância às recentes pesquisas, a utilização da IA, em nível mundial, cresce consideravelmente. Posto isto, este estudo se configura em natureza exploratória, com auxílio de pesquisa documental, a partir do acesso à base de dados de patentes inglesa Questel Orbit Intelligence. Nesse contexto, por meio da metodologia PRISMA, identificaram-se 87.959 patentes depositadas sobre o tema, em âmbito mundial, entre os anos 2003 e 2022. Ademais, há um crescimento acentuado de depósitos de patentes de IA a partir de 2015. Notou-se, também, a China como propulsora internacional no desenvolvimento dessa tecnologia, principal nação depositante. Diante disso, constatou-se que a publicação de patentes de IA acompanha o progresso exponencial de tal tecnologia, levando em consideração os aspectos de proteção de propriedade intelectual e de segurança jurídica, o que possibilita vantagens competitivas frente aos concorrentes, obtidas por intermédio do direito à concessão de patentes.
BREVES AVALIAÇÕES SOBRE PERSONALIDADE E RESPONSABILIDADE JURÍDICAS: UMA DISCUSSÃO SOBRE TECNOLOGIAS DE INTELIGÊNCIA ARTIFICIAL EM PATENTES
Authors: Sampaio Giovanna Martins , Belmino dos Santos João Antonio
Published: September 2023

A pesquisa pautou-se numa abordagem interdisciplinar sobre a ética jurídica envolvida na Era Digital, especialmente no que diz respeito ao uso de Inteligência Artificial no desenvolvimento de patentes como contorno; Além disso, os estudos abrangeram uma visão sobre a questão da responsabilidade civil, no âmbito amplo do Direito Contratual e das licenças. A pesquisa abordou as diferentes teorias e perspectivas sobre capacidade jurídica, direito privado e direitos da personalidade, ilustrando o conceito teórico de justiça para fundamentar/embasar a problemática ética decorrente do uso da IA. Portanto, este trabalho de pesquisa englobou as vantagens e desvantagens envolvidas no cenário da Inteligência Artificial, demonstrando o desempenho e os resultados aprimorados na área de propriedade industrial, de acordo com práticas e técnicas empresariais e parâmetros éticos que devem ser perseguidos pela sociedade, para desenvolver uma uso transparente, confiável, e explicável da Inteligência Artificial como uma ferramenta especialmente relacionada ao sistema de patentes. Além disso, os estudos abordaram sumariamente os aspectos regulatórios e as políticas legislativas da IA ​​nos contextos internacional e europeu, fornecendo um quadro de direito comparado. Consequentemente, para alcançar este esforço multidisciplinar, uma perspectiva também centrada na análise de dados teve que ser aplicada, empregando principalmente o método e os esquemas funcionais, visando melhor abordar o uso da IA ​​na propriedade intelectual e suas consequências. Foi apresentada uma pequena introdução aos conceitos relevantes do cenário de IA, assim como os leitores encontrarão a contextualização de alguns outros conceitos ao longo desta tese; mais tarde, foi introduzida – e necessariamente criticada – a ideia de um esquema de seguro obrigatório para essas tecnologias de inteligência artificial; Ainda, o trabalho abordou algumas das questões éticas, de transparência e jurídicas envolvidas nessa problemática, e para isso, foram aqui abarcados alguns comentários sobre o marco contratual e as mudanças trabalhistas, a fim de chegar à principal conclusão do uso da IA ​​como ferramenta para auxiliar na “entrega” de inovações, “invenções” e melhorias do sistema de Patentes na totalidade; Com relação às limitações do presente trabalho, visto que o tema vem sendo bastante discutido entre áreas afins, o objetivo foi abordar os principais pontos jurídicos da responsabilidade civil e dos problemas éticos, a partir das suas noções básicas, portanto, outras ideias poderiam ser elaboradas e esculpidas.
REDESCOBRINDO A COLETIVIDADE NO ÂMBITO DA PROPRIEDADE INTELECTUAL
Authors: Gonçalves Vitor da Silva
Published: September 2023

O conceito de commons se originou no campo material, mas, nas últimas décadas, foi ampliado para o campo da propriedade intelectual, como oposição a restrições historicamente construídas, promovendo modelos de acesso aberto e colaborativos. Nesse sentido, o presente trabalho realizou, por meio de pesquisa bibliográfica, uma síntese histórica dos commons e a construção de um paralelo entre os processos ocorridos no âmbito da propriedade sobre bens materiais e da propriedade intelectual. É observado que, na antiguidade, esta primeira possuía um aspecto mais coletivo do que privado, mas passou por um processo de fechamento, tornando-se majoritariamente individual. Já os bens imateriais, também se apresentavam como coletivos e passaram por um processo similar de fechamento, a partir do reconhecimento da sua forma de propriedade e criação de leis para sua proteção. Entretanto, diferentemente dos bens materiais, houve uma reviravolta: o resgate e readaptação das antigas ideias de propriedade compartilhada e criação colaborativa, promovendo um movimento de reabertura dos commons imateriais.
EDUCAÇÃO E ARQUIVOS
Authors: Sabino Fernanda de Matos Tostes , Gomes Priscila Ribeiro
Published: September 2023

Este artigo é resultado do desenvolvimento de pesquisa relacionada ao Programa de Iniciação Científica da Universidade Federal do Estado do Rio de Janeiro, que culminou na escrita de trabalho de conclusão do curso de Arquivologia.  O objetivo deste estudo voltou-se à realização de um levantamento acerca da produção bibliográfica em torno das interlocuções que envolvem os campos da Arquivologia e Educação, a partir de dois eventos:  Congresso Nacional de Arquivologia (CNA) e a Reunião de Ensino e Pesquisa em Arquivologia (REPARQ), ambos eventos desde a data de criação. Além de apresentar um breve histórico sobre os eventos, a pesquisa também possibilitará aos interessados nos diálogos entre Arquivos e Educação identificar as possibilidades dos temas apresentadas nos eventos. Para atingir os objetivos propostos foram utilizados os métodos de pesquisa bibliográfico e documental acerca das produções do CNA e Reparq, que serviram como base para uma posterior análise comparativa.
Ethyl Acetate Fraction from Hedyotis Diffusa Plus Scutellaria Barbata
Inhibits the Progression of Breast Cancer via Targeting LMO1 and
AKT/Mtor Signaling Pathway
Authors: Li Zhiyuan , Li Jingwei , Liu Xiaofei , Sun Ziyuan , Sun Xiaohui
Published: September 2023

Background:

Traditional Chinese medicines are widely used in cancer treatment. Scutellaria
barbata and Hedyotis diffusa herb pair (SH) has an anticancer effects in various tumors.
However, the specific mechanism of SH in breast cancer remains unclear.

Methods:

In the present research, we investigated the effect and regulatory network of SH in in
breast cancer. CCK8, colony formation, transwell, wound healing and flow cytometry analysis
were used for the detection of cell function.

Results:

Ethyl acetate fraction from SH at an equal weight ratio (EA11) could inhibit the proliferation,
migration and invasion of MCF7 and MDA-MB-231 cells. It also induced apoptosis in these
two cell lines by downregulating Bcl2 and upregulating Bax and Cleaved-Caspase3. SH reduced
the activation of the AKT/mTOR signaling pathway and the expression of p70S6K. Sequencing
results showed that LMO1 was significantly downregulated in SH-treated cells compared with control
cells. Importantly, overexpression of LMO1 attenuated the inhibitory effect of SH on cell proliferation
and invasion and induced inflammatory tumor microenvironment.

Conclusion:

In conclusion, the SH herb pair inhibited the proliferation and metastasis through
downregulating LMO1 expression and reducing the activation of the AKT/mTOR signaling pathway.
LMO1 has the potential as a new target in the treatment of breast cancer.
Role of Bioactive Compounds, Novel Drug Delivery Systems, and
Polyherbal Formulations in the Management of Rheumatoid Arthritis
Authors: Rana Neha , Gupta Piyush , Singh Hridayanand , Nagarajan Kandasamy
Published: September 2023

Rheumatoid Arthritis (RA) is an autoimmune disorder that generally causes joint synovial
inflammation as well as gradual cartilage and degenerative changes, resulting in progressive
immobility. Cartilage destruction induces synovial inflammation, including synovial cell hyperplasia,
increased synovial fluid, and synovial pane development. This phenomenon causes articular
cartilage damage and joint alkalosis. Traditional medicinal system exerts their effect through several
cellular mechanisms, including inhibition of inflammatory mediators, oxidative stress suppression,
cartilage degradation inhibition, increasing antioxidants and decreasing rheumatic biomarkers.
The medicinal plants have yielded a variety of active constituents from various chemical
categories, including alkaloids, triterpenoids, steroids, glycosides, volatile oils, flavonoids, lignans,
coumarins, terpenes, sesquiterpene lactones, anthocyanins, and anthraquinones. This review sheds
light on the utilization of medicinal plants in the treatment of RA. It explains various phytoconstituents
present in medicinal plants and their mechanism of action against RA. It also briefs about the
uses of polyherbal formulations (PHF), which are currently in the market and the toxicity associated
with the use of medicinal plants and PHF, along with the limitations and research gaps in the
field of PHF. This review paper is an attempt to understand various mechanistic approaches employed
by several medicinal plants, their possible drug delivery systems and synergistic effects for
curing RA with minimum side effects.
Recent Progress in Layered Double Hydroxides-based Materials as Sustainable Nanoadsorbents for Hazardous Pollutants Recovery from Aqueous Medium
Authors: Dib Mustapha , Kacem Marieme , Tajuddin Nazrizawati A.
Published: September 2023

The increasing prevalence of hazardous pollutants in water poses a significant
global threat to the environment and human health. To address this issue, various methodologies
have been developed for the determination and removal of harmful contaminants,
with layered double hydroxides (LDHs)-based materials emerging as promising
adsorbents. This review focuses on recent advancements in the application of LDHsbased
materials for the removal of specific harmful pollutants, such as selenium, fluoride,
heavy metals, and organic dyes, from aqueous solutions. Heavy metals and organic
dyes, in particular, are major contributors to environmental pollution, necessitating effective
and eco-friendly treatment methods.
Design and Simulation of a CdTe/C2N/SnO2 Trilayer Photovoltaic Cell viaSCAPS-1D
Authors: Meena Rupanjali , Lata Lalit kumar , Jain Praveen Kumar , Sethi Sarabjeet Singh
Published: September 2023

Introduction:

Simulation of cadmium telluride (CdTe)-based solar cells (CdTe/C2N/SnO2) using Solar Cell Capacitance Simulator-1D (SCAPS-1D) has been presented in this article.

Method:

C2N was introduced as a buffer layer, SnO2 was introduced as a window layer, and CdTe was introduced as an absorber layer.

Result:

The impact of the thickness of the CdTe, SnO2, and C2N layers, the defect density and carrier concentration of the CdTe layer, and the impact of ambient temperature were analyzed.

Conclusion:

The optimized solar cell demonstrated a maximum power conversion efficiency (PCE) of 22.41% with an open circuit voltage (VOC) of 1.07 V, a short circuit current density (JSC) of 23.59 mA/cm2, and an FF of 88.51%, indicating huge promise in low-cost solar energy harvesting.
Nintedanib as the First Treatment for Group of Progressive Interstitial
Lung Diseases: A Review of Patent Literature
Authors: Trivedi Madhavkumar Dilipbhai , Dubal Gaurang , Vora Pratik Ashwinbhai
Published: September 2023

Nintedanib is a competitive inhibitor of non-receptor tyrosine kinase (nRTKs) and receptor
tyrosine kinase (RTKs). Nintedanib is a substrate for the P-glycoprotein transporter, which
returns ingested substances to the gastrointestinal lumen. At present, Nintedanib is being prescribed
for individuals diagnosed with idiopathic pulmonary fibrosis (IPF). This assessment provides
a concise overview of the latest patents pertaining to Nintedanib. The patents covered in this
analysis are categorized into sections, including patents related to the active ingredient, polymorph,
formulation, and treatment method. The purpose of this compilation is to offer researchers
convenient access to all the relevant patents in a single resource. Information was collected from
diverse web databases, including both paid and free sources. Paid databases, such as Orbit® and
SciFinder® were utilized as examples. On the other hand, free databases, such as the European
Patent Office's Espacenet®, WIPO Patentscope® the Indian patent database, and Google Patents,
were also accessed for data gathering purposes. The orange-book listed patents for Nintedanib are
set to expire in July 2029. These patents explore various excipients to address the solubility issue
in the long-term storage of the formulation. However, despite these efforts, there is still a need for
further research to enhance the properties of the Nintedanib formulation. Extensive research has
been conducted on multiple methods for manufacturing Nintedanib and its formulations. This
dynamic study has the potential to create opportunities for numerous generic companies to
enter the United States market. This, in turn, will improve healthcare accessibility by lowering
costs.
Therapeutic Importance and Pharmacological Activities of Norisoboldine
in Medicine for the Treatment of Human Disorders
Authors: Patel Dinesh Kumar , Patel Kanika
Published: September 2023

Background:

Natural products constitute a unique source of chemical compounds with vast multi-target potential for the treatment of complex human disorders. Phytochemicals are pure phytoconstituents of plants, mainly responsible for their therapeutic potential and pharmacological activities. Natural products isolated from medicinal plants have been used as a lead source of drug. Norisoboldine is an important isoquinoline alkaloid found to be present in the dry root of Lindera aggregate.

Methods:

In the present paper, scientific data of norisoboldine have been collected from Google, Google Scholar, PubMed, Science Direct and Scopus and analyzed in order to know the biological potential and therapeutic effectiveness of norisoboldine in medicine. Scientific data of medicinal importance and therapeutic potential of norisoboldine has been collected and analyzed in the present work. Moreover, all the collected scientific data have been separated into different sub-section i.e. Medicinal importance, pharmacological activities and analytical aspects. Detailed pharmacological activity data of norisoboldine have been analyzed in the present work to know the therapeutic effectiveness of norisoboldine in medicine. Analytical data of norisoboldine have also been collected and analyzed in the present work.

Results:

Scientific data analysis revealed the biological importance of isoquinoline alkaloids in medicine. Isoquinoline alkaloids are pure, active phytochemical present in several natural edible products including vegetables, plants, and fruits. Norisoboldine has a biological effect on arthritis, colitis, apoptosis, osteoclast differentiation, inflammatory pain, renal ischemia-reperfusion injury, acute lung injury, pro-inflammatory cytokines, tumor, regulatory T cells, and endothelial cell migration. However nanoemulsifying drug delivery system of norisoboldine has also been prepared in order to get better therapeutic value. Further analytical parameters of norisoboldine were also discussed in the present work in order to get the scientific information of separation, isolation and identification parameter of norisoboldine.

Conclusion:

Present work revealed the therapeutic potential of norisoboldine in medicine.
Model Aliran 2-D untuk Memprediksi Gerusan dan Sedimentasi di Saluran Jakabaring Sport City (JSC) Palembang
Authors: Syarifudin Achmad
Published: September 2023

Penelitian ini bertujuan untuk mengkaji gerusan (erosi) dan sedimentasi (deposisi) di saluran utama Jakabaring Sport City (JSC) yang berada di Sub-DTA (Daerah Tangkapan Air) Jakabaring. Metode penelitian yang dipakai dalam kajian ini menggunakan pendekatan model fisik aliran 2-Dimensi (2-D) dengan saluran standar (standard flume) yang ada di laboratorium Hidrolika Fakultas Teknik Universitas Bina Darma Palembang. Data hasil penelitian di analisis dimensi dengan metode Langhaar untuk mendapatkan hubungan antara variabel terkait tersebut untuk mendapatkan parameter tak berdimensi. Hasil penelitian diperoleh kedalaman gerusan (de) maksimum sebesar 0,9 cm terjadi pada waktu “running test” selama 5 menit di model dengan nilai R2=0,887 atau R=0,7867 berarti 78,67% kedalaman gerusan (erosi) yang terjadi dipengaruhi oleh faktor waktu (t), jarak (x), dan kecepatan aliran (v). Sedangkan besarnya sedimentasi (deposisi) maksimum sebesar 0,5 cm terjadi pada waktu “running test” selama 5 menit di model dengan nilai R2=0,805 atau R=0,6480 artinya terdapat 64,80% sedimentasi (deposisi) dipengaruhi oleh faktor waktu (t), jarak (x), dan kecepatan aliran (v).
تحلیل الکفاءة الانتاجية والاقتصادية لنظم انتاج محصول الخيار في محافظة السلیمانیة للموسم الزراعي (2021_2022)
Authors: Aziz Nigar Jebar , Huseen Khalid Mohammad
Published: September 2023

يسعى الدراسة الى تحليل الكفاءة الانتاجية والاقتصادية لمحصول الخيار وتقييم نظم الانتاج الثلاث (نظام المكشوف –الزراعة التقليدية، الزراعة بنظام البيوت البلاستيكية ، نظام الزراعة بالانفاق  البلاستيكية) المختلفة اقتصاديا في محافظة السليمانية . وذلك باستخدام بيانات اولية (مباشرة) تم تجميعها لعينة من مزارعي (منتجي) محصول الخيار في النظم الثلاثة في الموسم الزراعي 2021-2022. 
   توصلت الدراسة الى تحديد العناصر الانتاجية الاكثر اهمية والاكثر تاثيرا بانتاج محصول الخيار المنتج بنظم الانتاج الثلاثة وهما كل من السماد العضوي والسماد النتروجيني ، وقد تم تقدير دالة الاستجابة المحصولية المقدرة واشتقاق دالة منحى الناتج المماثل وخط منحى التوليفات الاقل تكلفة . وجد الانتاج الفعلي لمحصول الخيارفي محافظة السليمانية يتم في مرحلة الانتاج الاولي مرحلة (غير اقتصادية) في النظم الثلاثة حيث بلغ حوالي 16 طن للدونم في حالة الزراعة المكشوفة ونحو(40 طن للدونم) في نظام الزراعة بالبيوت البلاستيكية ونحو(24 طن للدونم) في حالة نظام الزراعة بطريقة الانفاق.قدر صافي العائد المتحقق للطن حوالي (9934 الف دينار) في نظام الزراعة بالبيوت البلاستيكية ثم ياتي الانتاج في نظام الانفاق بصافي عائد للطن حوالي (3511 الف دينار) وجاء مستوى الكفاءة الاقتصادية لمحصول الخيار في نظام الزراعة المكشوفة اقل بالمقارنة بالنظامين السابقين حيث قدر عائد الطن من محصول الخيار بحوالي (1231 الف دينار) فقط .
   توصي الدراسة بالاستخدام الامثل للكميات المثلى الاقتصادية من عنصري الانتاج السماد العضوي والسماد النتروجيني كونهما من العناصر الفعالة لزيادة الانتاج
لمحصول الخيار في النظم الثلاثة ، وذلك من خلال زيادة كفاءة استخدامهما بهدف الوصول الى الحجم الاقتصادي وتقليل الخسارة التي يتكبدها المزارع بسبب الانتاج بمرحلة غير اقتصادية ( المرحلة الاولى ) .
A Survey of Patient Demographics in Inflammatory Skin Disease Case Reports
Authors: O'Hagan Ross , Caldas Stella A , Brunner Patrick M , Ungar Benjamin
Published: September 2023

Case reports serve many functions in the medical literature. We explore patient demographics in case reports for common inflammatory skin diseases.
Effect of Pretreatments and Drying Methods on The Physicochemical and Antioxidant Properties of Whole Eggplant (Solanum aethiopicum) Flour
Authors: Ukom Anthony , Egbujor Dennis , Nwanagba Lilian , Okparauka Immaculata
Published: September 2023

Sliced eggplant was pretreated (blanching and citric acid dip), -dried (oven and sun), then pulverized to flour. Physicochemical and antioxidant properties were evaluated using standard methods. The results showed increases in protein, moisture, fat, ash, crude fiber, and carbohydrate contents. They ranged from 7.78–8.39%, 8.90–10.14%, 4.32–5.28%, 0.77–0.91%, 10.72–13.43%, and 63.35–65.77%, respectively. Citric acid treatment and dried methods increased the minerals content for sodium (121.77–125.87 mg/100g), zinc (3.18–5.77 mg/100g), potassium (489.53–628.58 mg/100g), magnesium (68.86–75.39 mg/100g) and iron (8.91–11.82 mg/100g) than the blanched treatment. Functional properties of eggplant flour revealed that bulk density (0.42–0.50%,), oil absorption capacity (0.64–4.85%), and wettability (1.43–4.35%,) increased with citric acid and sun-drying method while swelling index (1.25–1.61%) and water absorption capacity (3.85–5.61%) increased with citric acid and oven drying method. Total polyphenol (26.49–29.78 mg GAE/mL), flavonoid (22.12–11.38 mg QE/mL), ABTS (52.38–61.34 Mmol/100 mL), DPPH (62.78–68.48%) and FRAP (58.67–65.36 Mmol/100mL) showed significant (p<0.05) increases in citric acid and dried methods. From the results, the physicochemical and antioxidant properties of eggplant flour were positively affected by citric acid pre-treatments in sun and oven-dried methods.
The Perception of internally displaced Persons and the role of Social Actors in the Amelioration of their Living Conditions in Cameroon
Authors: Muluh Khan Julius , Kunock Afu Isaiah , Bertrand Djouda Feudjio Yves
Published: September 2023

The controversy surrounding the concept “internally displaced persons” is old as the history of migration but the concept is relatively pronounced in Cameroon with multidimensional perceptions from host populations and social actors whose role vary from the provision of material assistance to psychosocial counseling. The perception of the displaced from the socio-political crisis in the North West and South West regions of Cameroon differs and their plight is partially neglected and not directly addressed by national and international instruments that Cameroon have had to ratify. With competition amongst themselves and with host communities over the use of scarce resources, this paper has as objective to investigate how these internally displaced persons are perceived in host communities and to provide an indebt analysis of the role that social actors play in the transformation of the living conditions of the displaced. To arrive at the required results, the qualitative research method was used with interviews, life stories, and observations. The data collected was transcribed and analyzed using the content analysis. After defining the population, a sample unit was selected with care and precision (Copi, & Cohen, 2011) using the purposive snowball sampling technique as opposed to stratified and cluster sampling techniques (Cohen and al., 2007). The results revealed that the affected population are in a transgression from conflicts to the reality of their lives confirmed by the mutual suspicion and conflictual relationships between them. An analysis of the perception of host communities by IDP’s, was characterized as a deceptive social perception and that of anti-sociality instilling in them the feelings of auto-marginalization. However, some members of the host community though lacking resources exhibited solidarity and assistance that helped improve their standards of living. The results also revealed the settlement challenges, with some family members and friends serving as “de factor NGO”, portraying the perception of partial neglect and inadequate treatment of IDP’s and the host communities by local state authorities, Non-Governmental Organizations and other social actors. Hence, necessitating an urgent politico-institutionalized response on the plight of the displaced and host communities in Cameroon.
Performance Enhacement of MIMO-CDMA system using Adaptive Non-Coherent Receiver
Authors: Sreesudha P , Rajender G
Published: September 2023

Abstract: Wireless communication systems are a key means to meet the increasing demands for greater capacity and increased quality-of-service. MIMO systems have the potential to reduce the operational power consumption and enable the use of low complexity schemes for suppressing MU interference (MUI). One of the cellular communication technologies is CDMA. The combine of MIMO and CDMA is most able technique beyond 4G technologies. The DS-CDMA system is widely known for removing the effects of Multiple Access Interference (MAI) which degrades the performance of the system. The addition of interference cancellation which is a sub-optimal procedure of multiuser detector (MUD) in a DS-CDMA-MIMO system can greatly enhance its performance relative to that of conventional CDMA receiver and this can be verified with the help of MATLAB
Random unitaries, Robustness, and Complexity of Entanglement
Authors: Odavić J. , Torre G. , Mijić N. , Davidović D. , Franchini F. , Giampaolo S. M.
Published: September 2023

It is widely accepted that the dynamic of entanglement in presence of a generic circuit can be predicted by the knowledge of the statistical properties of the entanglement spectrum. We tested this assumption by applying a Metropolis-like entanglement cooling algorithm generated by different sets of local gates, on states sharing the same statistic. We employ the ground states of a unique model, namely the one-dimensional Ising chain with a transverse field, but belonging to different macroscopic phases such as the paramagnetic, the magnetically ordered, and the topological frustrated ones. Quite surprisingly, we observe that the entanglement dynamics are strongly dependent not just on the different sets of gates but also on the phase, indicating that different phases can possess different types of entanglement (which we characterize as purely local, GHZ-like, and W-state-like) with different degree of resilience against the cooling process. Our work highlights the fact that the knowledge of the entanglement spectrum alone is not sufficient to determine its dynamics, thereby demonstrating its incompleteness as a characterization tool. Moreover, it shows a subtle interplay between locality and non-local constraints.
Ayudas diagnósticas y diagnóstico diferencial de la enfermedad de Pompe
Authors: Marentes-Cubillos Alba Lucia , Carrillo-Villa Sandra , López-Cáceres Andrea del Pilar , Mesa-Mosquera Maria Paula
Published: September 2023

Introducción: la enfermedad de Pompe (EP) o glucogenosis tipo II es una enfermedad autosómica recesiva causada por mutaciones en el gen GAA que codifica para la proteína alfa-1,4-glucosidasa. Su deficiencia lleva a un almacenamiento anormal de glucógeno en los lisosomas de varias células, a través de los diferentes tejidos, lo que causa un compromiso musculoesquelético predominante.
Contenidos: los fenotipos de la enfermedad dependen de las variantes genéticas y de los niveles de la actividad enzimática residual. La enfermedad se presenta como EP de inicio infantil, EP de inicio tardío y EP intermedio, por lo que es de suma importancia su diagnóstico temprano, por medio de estudios moleculares como la secuenciación de Sanger y la secuenciación de nueva generación.
Conclusiones: se ha demostrado, mediante diferentes estudios, que las variaciones genéticas pueden diferir entre etnias, y es importante su caracterización molecular para determinar el tratamiento más adecuado, de acuerdo con el estado del material inmunológico de reacción cruzada (CRIM).
dinero electrónico como herramienta clave para promover la inclusión financiera
Authors: Ramos Zaga Fernando Antonio
Published: September 2023

La inclusión financiera en Perú se enfrenta a dificultades considerables, debido a los bajos niveles de acceso a servicios financieros como préstamos y cuentas de ahorro. Para hacer frente a este desafío, el dinero electrónico surge como una herramienta que, potencialmente, podría llegar a las poblaciones desatendidas por la banca tradicional. Por ende, el uso generalizado de la telefonía móvil en Perú es fundamental para promover la inclusión financiera en poblaciones que se encuentran en situación de vulnerabilidad económica. En ese sentido, el presente artículo tiene por objetivo analizar el marco legal del dinero electrónico, así como las barreras de acceso en la oferta y demanda de servicios financieros. Se concluye que el dinero electrónico puede llevar servicios financieros esenciales a poblaciones antes desatendidas, aprovechando la infraestructura móvil existente.
The development of proton-electron math e-comic to improve special needs students’ mathematical concepts understanding
Authors: Harisman Yulyanti , Fitrani Dwina  , Minora Longgom Nasution  , Mohd Hasril Amiruddin  , Hamdani Syaputra
Published: September 2023

Technology-based learning media is still lacking for special needs students in mathematics. Based on observations and interviews with Special School (SLB) teachers, the learning media used were still monotonous, such as picture books and writing using a blackboard. This research aims to develop e-comic math using the App Pixton application, which is valid and practical for children with special needs in SLB. The research method used is Plomp model development research in the prototype development phase: self-evaluation, expert review, and one-to-one evaluation. The data collection instruments used were a questionnaire and mathematical concepts on addition and subtraction topics for students with special needs. The research subjects were 21 students and 5 teachers from 5 different special schools in 5 West Sumatra, Indonesia cities. The study results show that the media developed is valid and practical for students with deaf and intellectual disabilities. This research implies that teachers must be able to develop other IT-based learning media to help students with special needs learn mathematics like normal children.
A Full W-Band Miniaturized Waveguide-to-Microstrip Transition and the Simple One-kit De-embedding Method for Planar Antenna Measurement
Authors: Tsai Cheng-Hua , Tarng Jenn-Hwan , Tsai Ching Han , Chung Shyh-Jong
Published: September 2023

For measuring the planar microstrip patch antenna in millimeter-wave
frequency range, the transition is usually required to connect to the
waveguide interface of frequency extender then a vector network
analyzer. The conventional solution is a two-stages transition by a
waveguide-to-coaxial transition as a first stage and an end-launch
adaptor as the second. Some works had proposed a directly transition
from a waveguide interface to a planar microstrip interface. But the
transitions of in-line structure will easily scattering that will affect
the measured results, and the vertical structure will encounter the
trade-off from the size of back cavity and the bandwidth performance. In
this paper, a vertical type, waveguide-to-microstrip (W2ML) transition
structure is proposed by the adoption of an aperture-stacked microstrip
patch antenna (ASMPA) to have the performance of ultra-wide bandwidth
and miniaturize the size. In addition, the characteristic of ASMPA W2ML
transition can easily been by one-kit de-embedding method that only THRU
calibration kit with time gating process is required. The consistency of
the simulated result compared to the measured-calculated result exhibit
the effectiveness of the proposed ASMPA W2ML transition for measuring a
real planar microstrip patch antenna in millimeter-wave band.
Visual-Numeric Endometriosis Scoring System (VNESS) for mapping surgical findings: A validation study.
Authors: Mondelli Benedetto , Khazali Shaheen , Fleischer Kyle , Bachi Averyl , Adamczyk Michael , Lemos Nucelio , Krentel Harald , Vashisht Arvind , Abdalla Abdelmonim , Mohazzab Arash , Delanerolle Gayathri , Possover Marc , Padmehr Roya , Shadjoo Khadijeh , MOAWAD GABY , Lee Ted , Saridogan Ertan
Published: September 2023

Objective The aim of this study was to assess inter-rater
reliability for components of the Visual-Numeric Endometriosis Scoring
System (VNESS). VNESS is a novel system for describing surgical findings
in each compartment of the pelvis in a way that is simple to use,
visually intuitive and mirrors a laparoscopic image of the pelvis.
Design Validation study using short surgical laparoscopic video
clips. Setting Anonymized video clips of endometriosis surgery
scored by 50 Gynaecologists from 12 countries. Population
Gynaecologists as scores of short surgical clips selected from a series
of endometriosis procedures performed between 2012 and 2022.
Methods 50 gynaecologists scored 93 short surgical videoclips
using VNESS. 4650 scores were compared against a reference score and
analysis was performed to assess inter-rater reliability. Main
outcome measures The outcome measures were percentage agreement between
given and reference scores, as well as intra-class correlation
coefficients (ICC), Cohen Kappa and Quadratic Weighted Kappa
Coefficients were calculated to evaluate inter-rater reliability.
Results The highest and lowest percentage agreement with the
reference score was seen in VNESS 4 (full thickness disease, 97%
perfect agreement) and VNESS 1 (superficial disease, 53% perfect
agreement) respectively. The intraclass correlation coefficient showed
strong inter-rater reliability for all VNESS compartments except the
vagina. Conclusions This study suggests that VNESS has
excellent inter-observer reliability. Correlation is stronger with more
severe disease.
Representation of Women in the Layangan Putus Film Series: Semiotic Analysis of Roland Barthes
Authors: Hanifah Ummy , Ningsih Titiek Surya
Published: September 2023

The film has the power to influence gender ideology. The preservation of gender ideology can be noticed in the portrayal of women as weak people who are always intimidated both physically, sexually, and economically. The image of women as weak creatures is depicted in the Layangan Putus film series. These film series reach the highest rank in several Southeast Asian countries. The film describes a wife's pressure from her husband's affair and her struggle to overcome it. This study aims to analyze the representations of women in the context of images and scenarios in a film shown in the film series Layangan Putus using Roland Barthes' semiotic approach. Barthes introduces the concept of denotation, connotations, and myths. The results revealed that the denotation analysis and connotation level in the Layangan Putus film series confirm women's opposition to gender roles. Furthermore, this opposition aligns with Liberal Feminism seeking to liberate women from male domination. Liberal feminists aim to liberate women from gender-based constraints, challenging the lower status assigned to them solely due to their sex. On the other hand, true equality can be achieved by embracing androgynous perspectives, recognizing that both men and women possess characteristics of femininity and masculinity.
Challenges in Incorporating English as the Medium of Instruction at King Saud bin Abdulaziz University for Health Sciences
Authors: Alkhateeb Abdulelah , Alhawsawi Sajjadllah
Published: September 2023

In contexts where English is not a mother tongue, several institutions implement English as the medium of instruction. This paper argues that Saudi students pursuing tertiary education in scientific disciplines like health sciences must study in English-medium settings where they encounter several academic challenges related to the English language. Pre-university education for Saudi students is conducted in Arabic, which may have resulted in a jarring transition when they were expected to be instructed in English at the university. This abrupt change in the instruction medium challenges students’ English language proficiency. This paper aims to answer this question “What do perspectives students and instructors at KSAU-HS have regarding the challenges of implementing EMI in CAMS-A? ” It may also question the institution’s language policy and the quality of its educational outcomes. By using data from semi-structured interviews and classroom observations, the findings of this paper attempt to comprehend challenges such as 1) pre-university English language preparations, 2) misaligned expectations between content instructors and English instructors regarding improving students’ English language, 3) time and effort in preparing and delivering lectures using EMI, and 4) impeding students’ comprehension of content knowledge and driving them to rote memorization. This paper discusses these obstacles to provide potential explanations and solutions by calling into question the monolingual bias of EMI programs in Saudi Arabia.
High-speed turnout as part of the track
Authors: Dyduch Janusz , Paś Jacek
Published: September 2023

This paper presents the classification and construction of high-speed railway turnouts operated on European railway lines. The existing computer programs supporting the diagnostics of high-speed railway turnouts with the most common causes of failures originating from infrastructure elements were analyzed. The authors point to the need for integration of high-speed turnouts as a single system containing modern point machine control of switch area and swing nose crossing area with induction heating of moving turnout elements. Attention was also paid to the need to use appropriate means of transport dedicated for railway turnouts in order to improve the initial quality of the product.