bluuebunny/crossref_metadata_2025 huggingface dataset:
ASSESSMENT OF BENEFITS OF URBAN AGRICULTURE IN EDO AND OYO STATES, NIGERIA
Authors: EDEOGHON Clara Obehi. , AJAYI Michael Tunde
Published: October 2015

The study assessed benefits of Urban Agriculture in Edo and Oyo states, Nigeria. Data were collected from 345 urban farmers in six cities using a structured questionnaire and interview schedule. Findings showed that respondents' perceived benefits were being able to eat balanced meals at all times from farm produce (χ= 4.24), income from urban agriculture improved respondents' standard of living (χ= 4.15) and ability to save money from urban agriculture (χ= 4.08). Respondents' farming experience, farm size, cooperative membership and poultry enterprise had significant relationship with benefits from urban agriculture. Significant differences in benefits existed among the six cities.
Spanish Adaptation and Validation of the Posttraumatic Growth Inventory–Short Form
Authors: Castro Manuel Cárdenas , Delgado Jaime Barrientos , Alvarado Emilio Ricci , Rovira Darío Páez
Published: October 2015

The purpose of this article is to adapt and validate the short form of the Posttraumatic Growth Inventory (PTGI-SF) in Spanish. The scale consists of 10 items distributed in 5 posttraumatic growth dimensions measured in the original instrument. The psychometric properties and dimensionality of the scale are examined in a sample of college students (N = 681). Results lend support to the validity and reliability (α = .83) of the PTGI-SF. The dimensions of PTGI-SF show correlations ranging between .29 and .52. In addition, the inventory correlates significantly with deliberate rumination (r = .39) and the search for meaning in life (r = .32). The factor loadings of the items in the confirmatory factor analysis varied between .52 and .87, showing good fit indexes (comparative fit index = .97, Tucker-Lewis index = .93, relative fit index = .90, incremental fit index = .97, normed fit index = .96, and root mean square error of approximation = .05). Multigroup confirmatory factor analysis supported invariance of the PTGI-SF across the 2 groups. Finally, significantly higher PTGI-SF scores were observed in subjects who were actively looking for meaning in life, or had found it after a seeking process, than in subjects who had not looked for meaning in life or had given up because they had not been successful.
OC-k3 cells, an in vitro model for cochlear implant biocompatibility
Authors: Astolfi Laura , Simoni Edi , Martini Alessandro
Published: October 2015

Objective:

In patients with severe or deep hypoacousis, the cochlear implant represents the only way to recover the ability to hear. Nevertheless, the insertion of a silicone-embedded electrode in the cochlea may produce damage through pressure, shock, bleeding and tissue perforation, which could cause apoptosis and necrosis in the organ of Corti. Another variable is the use of different silicone materials. Although all embedding silicone compounds are medical grade biocompatible, their effects in the inner ear environment have never been tested. Our aim was to assess whether polydimethylsiloxane (PDMS) compounds employed in cochlear implants could be cytotoxic to inner ear cells, by exposing an in vitro organ of Corti cell line (OC-k3) to four PMDS compounds (three fluid and one elastomere) and verifying whether or not any one of these compounds could lead to cell death by apoptosis or necrosis.

Study design:

To obtain a toxicity curve, OC-k3 cells were exposed to PDMS compounds (octadimethylsiloxane, hexadimethylsiloxane, decamethylcyclopentasiloxane and a silicon rod) at different dilutions and time of exposure, testing vitality by flux cytofluorometry and fluorescence microscopy. Investigations were extended to molecular interactions between OC-k3 cells and PDMS, testing cell death markers by immunocytochemistry and real-time PCR.

Results:

Among the fluid PDMS compounds, decamethylcyclopentasiloxane induced the highest significant cell mortality (at 1:100 dilution) after 48 h of treatment, followed by octadimethylsiloxane (1:10) and hexadimethylsiloxane (1:5) at 24 h. The silicon rod did not show any inner ear cell toxicity.

Conclusion:

In our experimental conditions, the observed cell mortality was not caused by release of cytotoxic molecules by PDMS on OC-k3 cells, but by the formation by PMDS of a surface film preventing air exchange. From a biomolecular point of view, PDMS compounds appear suitable for electrode coating in cochlear implants.
The possible role of Vicorder® apparatus in the diagnostic protocol of inner ear diseases
Authors: Pirodda Antonio , Brandolini Cristina , Raimondi Maria Chiara , Pelligra Irene , Strocchi Enrico , Cicero Arrigo F. G. , Rosticci Martina , Borghi Claudio
Published: October 2015

Objective:

Cardiovascular risk factors are widely reputed to be a possible cause for hearing impairment, and the role of arterial stiffness as a cardiovascular risk predictor has been recently emphasized. For these reasons pulse wave velocity (PWV) could represent a useful parameter in order to rapidly assess or rule out the existence of an underlying overall deteriorating circulatory condition in cases of inner ear impairment.

Method:

In order to assess the real significance of PWV for audiological purposes, a study was carried out comparing this parameter in subjects with normal hearing and those with symmetrical sensorineural hearing loss.

Results:

The results suggested an apparent lack of correlation between arterial stiffness and hearing deterioration.

Conclusion:

The findings appear to indicate that the relationship between systemic circulation and inner ear function, when excluding acute and/or well identifiable impairment factors, is not as linear as expected.
Incidence and Risk Factors of Surgical Site Infection Following Cesarean Section at Dhulikhel Hospital
Authors: Shrestha S , Shrestha R , Shrestha B , Dongol A
Published: October 2015

Background Cesarean Section (CS) is one of the most commonly performed surgical procedures in obstetrical and gynecological department. Surgical site infection (SSI) after a cesarean section increases maternal morbidity prolongs hospital stay and medical costs.Objective The aim of this study was to find out the incidence and associated risk factors of surgical site infection among cesarean section cases.Method A prospective, descriptive study was conducted at Dhulikhel Hospital, department of Obstetrics and Gynaecology from July 2013 to June 2014. Total of 648 women who underwent surgical procedure for delivery during study period were included in the study. Data was collected from patient using structred pro forma and examination of wound till discharge was done. Data was compared in terms of presence of surgical site infection and study variables. Wound was evaluated for the development of SSI on third day, and fifth post-operative day, and on the day of discharge.Results Total of 648 cases were studied. The mean age was 24±4.18. Among the studied cases 92% were literate and 8% were illiterate. Antenatal clinic was attended by 97.7%. The incidence rate of surgical site infection was 82 (12.6%). SSI was found to be common in women who had rupture of membrane before surgery (p=0.020), who underwent emergency surgery (p=0.0004), and the women who had vertical skin incision (p=0.0001) and interrupted skin suturing (p=0.0001) during surgery.Conclusion Surgical site infection following caesarean section is common. Various modifiable risk factors were observed in this study. Development of SSI is related to multi-factorial rather than one factor. Development and strict implementation of protocol by all the health care professionals could be effective to minimize and prevent the infection rate after caesarean section.Kathmandu University Medical Journal Vol.12(2) 2014: 113-116
Distally Based Sural Faciocutaneous and Fascial (Adipofascial) Flap for Reconstruction of Distal Leg, Ankle and Foot Defects
Authors: Parajuli NP , Shrestha D , Panse N
Published: October 2015

Background Any soft tissue defect in distal leg, ankle and hind foot is still a challenging problem. There are various options for coverage of such defects, but the distally based sural neurocutaneous and neurofascial flap based on the sural nerve and superficial sural artery has been an important option.Objective To evaluate the efficacy of distally based sural flap in reconstruction of the distal leg, ankle and hind foot soft tissue defects.Method Seventeen patients with soft tissue defects over distal leg, ankle and hind foot were included in this study. All patients were treated with distally based sural flap. Most of the cases were due to trauma (16 cases) which compromised tendon and bone. One case was of malignant melanoma of sole of hind foot which required wide excision and soft tissue reconstruction with sural flap.Result In all cases defects were successfully covered. Three showed venous congestion and partial necrosis. One developed secondary infection. One flap failed completely. Mean follow up of patients was 20 months (6 – 36 months).Conclusion Sural flap is a good option for reconstruction of distal leg, ankle and foot defects.Kathmandu University Medical Journal Vol.12(2) 2014: 126-131
Ineffable Cultures or Material Devices: What Valuation Studies can Learn from the Disappearance of Ensured Solidarity in a Health Care Market
Authors: Zuiderent-Jerak Teun , Van Egmond Stans
Published: October 2015

Valuation studies addresses how values are made in valuation practices. A next - or rather previous - question becomes: what then makes valuation practices? Two oppositional replies are starting to dominate how that question can be answered: a more materially oriented focus on devices of valuation and a more sociologically inclined focus on ineffable valuation cultures. The debate between proponents of both approaches may easily turn into the kind of leapfrog debates that have dominated many previous discussions on whether culture or materiality would play a decisive role in driving history. This paper explores a less repetitive reply. It does so by analyzing the puzzling case of the demise of solidarity as a core value within the recent Dutch health care system of regulated competition. While “solidarity among the insured” was both a strong cultural value within the Dutch welfare-based health system, and a value that was built into market devices by health economists, within a fairly short time “fairness” became of lesser importance than “competition”. This makes us call for a more historical, relational, and dynamic understanding of the role of economists, market devices, and of culture in valuation studies.
Metabolic Profile and Inflammatory Responses in Dairy Cows with Left Displaced Abomasum Kept under Small-Scaled Farm Conditions
Authors: Klevenhusen Fenja , Humer Elke , Metzler-Zebeli Barbara , Podstatzky-Lichtenstein Leopold , Wittek Thomas , Zebeli Qendrim
Published: October 2015

Left displaced abomasum (LDA) is a severe metabolic disease of cattle with a strong negative impact on production efficiency of dairy farms. Metabolic and inflammatory alterations associated with this disease have been reported in earlier studies, conducted mostly in large dairy farms. This research aimed to: (1) evaluate metabolic and inflammatory responses in dairy cows affected by LDA in small-scaled dairy farms; and (2) establish an Animals 2015, 5 1022 association between lactation number and milk production with the outcome of metabolic variables. The cows with LDA had lower serum calcium (Ca), but greater concentrations of non-esterified fatty acids (NEFA) and beta-hydroxy-butyrate (BHBA), in particular when lactation number was >2. Cows with LDA showed elevated levels of aspartate aminotransferase, glutamate dehydrogenase, and serum amyloid A (SAA), regardless of lactation number. In addition, this study revealed strong associations between milk yield and the alteration of metabolic profile but not with inflammation in the sick cows. Results indicate metabolic alterations, liver damage, and inflammation in LDA cows kept under small-scale farm conditions. Furthermore, the data suggest exacerbation of metabolic profile and Ca metabolism but not of inflammation and liver health with increasing lactation number and milk yield in cows affected by LDA.
Effect of the Quality Property of Table Grapes in Cold Chain Logistics-Integrated WSN and AOW
Authors: Xiao Xinqing , Wang Xiang , Zhang Xiaoshuan , Chen Enxiu , Li Jun
Published: October 2015

Table grapes are very popular for their high nutritional and therapeutic value. The objective of this work was to study the effect of table grapes’ quality property in cold chain logistics for improving the transparency and traceability of table grapes’ cold chain logistics and ensuring the table grapes’ quality and safety. Temperature and relative humidity are monitored by adopting the wireless sensor network (WSN) as the fundamental network infrastructure and adaptive optimal weighted data fusion (AOW) for the adaptive data fusion. The cold chain process, firmness quality and adaptive data fusion of temperature and relative humidity were evaluated in an actual cold chain logistics. The results indicate that the WSN and AOW methods could effectively reflect the real-time temperature and relative humidity information and quality property, improve the transparency and traceability in the cold chain and ensure the preservation of the quality and safety of table grapes. The AOW performance analysis shows that the AOW, whose mean absolute error and mean relative error of the temperature data are 0.06 °C and 8.61% and relative humidity data are 0.12% and 0.23%, respectively, could fuse the sensor data accurately, efficiently and adaptively and meet the actual application requirements.
Design of the Secondary Optical Elements for Concentrated Photovoltaic Units with Fresnel Lenses
Authors: Chen Yi-Cheng , Chiang Hung-Wei
Published: October 2015

The goal of this presented study was to determine the optimum parameters of secondary optical elements (SOEs) for concentrated photovoltaic (CPV) units with flat Fresnel lenses. Three types of SOEs are under consideration in the design process, including kaleidoscope with equal optical path design (KOD), kaleidoscope with flat top surface (KFTS), and open-truncated tetrahedral pyramid with specular walls (SP). The function of using a SOE with a Fresnel lens in a CPV unit is to achieve high optical efficiency, low sensitivity to the sun tracking error, and improved uniformity of irradiance distribution on the solar cell. Ray tracing technique was developed to simulate the optical characteristics of the CPV unit with various design parameters of each type of SOE. Finally, an optimum KOD-type SOE was determined by parametric design process. The resulting optical performance of the CPV unit with the optimum SOE was evaluated in both single-wavelength and broadband simulation of solar spectrum.
Carrier-Envelope Offset Stabilized Ultrafast Diode-Pumped Solid-State Lasers
Authors: Schilt Stéphane , Südmeyer Thomas
Published: October 2015

Optical frequency combs have been revolutionizing many research areas and are finding a growing number of real-world applications. While initially dominated by Ti:Sapphire and fiber lasers, optical frequency combs from modelocked diode-pumped solid-state lasers (DPSSLs) have become an attractive alternative with state-of-the-art performance. In this article, we review the main achievements in ultrafast DPSSLs for frequency combs. We present the current status of carrier-envelope offset (CEO) frequency-stabilized DPSSLs based on various approaches and operating in different wavelength regimes. Feedback to the pump current provides a reliable scheme for frequency comb CEO stabilization, but also other methods with faster feedback not limited by the lifetime of the gain material have been applied. Pumping DPSSLs with high power multi-transverse-mode diodes enabled a new class of high power oscillators and gigahertz repetition rate lasers, which were initially not believed to be suitable for CEO stabilization due to the pump noise. However, this challenge has been overcome, and recently both high power and gigahertz DPSSL combs have been demonstrated. Thin disk lasers have demonstrated the highest pulse energy and average power emitted from any ultrafast oscillator and present a high potential for the future generation of stabilized frequency combs with hundreds of watts average output power.
In Vivo Electrochemical Analysis of a PEDOT/MWCNT Neural Electrode Coating
Authors: Alba Nicolas , Du Zhanhong , Catt Kasey , Kozai Takashi , Cui X.
Published: October 2015

Neural electrodes hold tremendous potential for improving understanding of brain function and restoring lost neurological functions. Multi-walled carbon nanotube (MWCNT) and dexamethasone (Dex)-doped poly(3,4-ethylenedioxythiophene) (PEDOT) coatings have shown promise to improve chronic neural electrode performance. Here, we employ electrochemical techniques to characterize the coating in vivo. Coated and uncoated electrode arrays were implanted into rat visual cortex and subjected to daily cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) for 11 days. Coated electrodes experienced a significant decrease in 1 kHz impedance within the first two days of implantation followed by an increase between days 4 and 7. Equivalent circuit analysis showed that the impedance increase is the result of surface capacitance reduction, likely due to protein and cellular processes encapsulating the porous coating. Coating’s charge storage capacity remained consistently higher than uncoated electrodes, demonstrating its in vivo electrochemical stability. To decouple the PEDOT/MWCNT material property changes from the tissue response, in vitro characterization was conducted by soaking the coated electrodes in PBS for 11 days. Some coated electrodes exhibited steady impedance while others exhibiting large increases associated with large decreases in charge storage capacity suggesting delamination in PBS. This was not observed in vivo, as scanning electron microscopy of explants verified the integrity of the coating with no sign of delamination or cracking. Despite the impedance increase, coated electrodes successfully recorded neural activity throughout the implantation period.
Direct Interaction between Carcinoma Cells and Cancer Associated Fibroblasts for the Regulation of Cancer Invasion
Authors: Yamaguchi Hideki , Sakai Ryuichi
Published: October 2015

The tumor stroma acts as an essential microenvironment of the cancer cells, which includes many different types of non-cancerous cells and the extracellular matrix (ECM). Stromal fibroblasts (SFs) are the major cellular constituents of the tumor stroma and are often called cancer-associated fibroblasts (CAFs). They are often characterized by α-smooth muscle actin (αSMA) expression, which is indicative of the myofibroblast phenotype and strong contractility. These characteristics contribute to the remodeling and stiffening of the stromal ECM, thereby offering an appropriate field for cancer cell invasion. Importance of the tumor stroma in cancer progression has recently been highlighted. Moreover, several reports suggest that stromal fibroblasts interact with adjacent cancer cells through soluble factors, exosomes, or direct cell-cell adhesion to promote cancer cell invasion. In this review, current models of the regulation of cancer cell invasion by surrounding fibroblasts are summarized, including our recent work on the interaction between stromal fibroblasts and scirrhous gastric carcinoma (SGC) cells by using a three-dimensional (3D) culture system. Further mechanistic insights into the roles of the interaction between cancer cells and stromal fibroblasts in cancer invasion will be required to identify novel molecular targets for preventing cancer cell invasion.
Application of a Coated Film Catalyst Layer Model to a High Temperature Polymer Electrolyte Membrane Fuel Cell with Low Catalyst Loading Produced by Reactive Spray Deposition Technology
Authors: Myles Timothy D. , Kim Siwon , Maric Radenka , Mustain William E.
Published: October 2015

In this study, a semi-empirical model is presented that correlates to previously obtained experimental overpotential data for a high temperature polymer electrolyte membrane fuel cell (HT-PEMFC). The goal is to reinforce the understanding of the performance of the cell from a modeling perspective. The HT-PEMFC membrane electrode assemblies (MEAs) were constructed utilizing an 85 wt. % phosphoric acid doped Advent TPS® membranes for the electrolyte and gas diffusion electrodes (GDEs) manufactured by Reactive Spray Deposition Technology (RSDT). MEAs with varying ratios of PTFE binder to carbon support material (I/C ratio) were manufactured and their performance at various operating temperatures was recorded. The semi-empirical model derivation was based on the coated film catalyst layer approach and was calibrated to the experimental data by a least squares method. The behavior of important physical parameters as a function of I/C ratio and operating temperature were explored.
Active Nuclear Import of Membrane Proteins Revisited
Authors: Laba Justyna , Steen Anton , Popken Petra , Chernova Alina , Poolman Bert , Veenhoff Liesbeth
Published: October 2015

It is poorly understood how membrane proteins destined for the inner nuclear membrane pass the crowded environment of the Nuclear Pore Complex (NPC). For the Saccharomyces cerevisiae proteins Src1/Heh1 and Heh2, a transport mechanism was proposed where the transmembrane domains diffuse through the membrane while the extralumenal domains encoding a nuclear localization signal (NLS) and intrinsically disordered linker (L) are accompanied by transport factors and travel through the NPC. Here, we validate the proposed mechanism and explore and discuss alternative interpretations of the data. First, to disprove an interpretation where the membrane proteins become membrane embedded only after nuclear import, we present biochemical and localization data to support that the previously used, as well as newly designed reporter proteins are membrane-embedded irrespective of the presence of the sorting signals, the specific transmembrane domain (multipass or tail anchored), independent of GET, and also under conditions that the proteins are trapped in the NPC. Second, using the recently established size limit for passive diffusion of membrane proteins in yeast, and using an improved assay, we confirm active import of polytopic membrane protein with extralumenal soluble domains larger than those that can pass by diffusion on similar timescales. This reinforces that NLS-L dependent active transport is distinct from passive diffusion. Thirdly, we revisit the proposed route through the center of the NPC and conclude that the previously used trapping assay is, unfortunately, poorly suited to address the route through the NPC, and the route thus remains unresolved. Apart from the uncertainty about the route through the NPC, the data confirm active, transport factor dependent, nuclear transport of membrane-embedded mono- and polytopic membrane proteins in baker’s yeast.
Scintigraphic Small Intestinal Transit Time and Defaecography in Patients with J-Pouch
Authors: Kjaer Mie , Simonsen Jane , Hvidsten Svend , Kjeldsen Jens , Gerke Oke , Qvist Niels
Published: October 2015

Objective methods for examination of pouch function are warranted for a better understanding of the functional result and treatment of dysfunction. The objective of this study was to evaluate the results of scintigraphic intestinal transit time and defaecography compared to the results of pouch function, mucosal condition and a questionnaire on quality of life (QoL). This cross-sectional study included 21 patients. Scintigraphic transit time and defaecography was determined with the use of Tc-99m. Pouch function was assessed by number of bowel movements, pouch volume, and continence. Pouch mucosal condition was evaluated by endoscopy and histology. Median transit time was 189 min (105–365). Median ejection fraction at defaecography (EF) was 49% (3–77) and 62% (17–98) after first and second defecation. Median pouch volume was 223 mL (100–360). A median daily stool frequency of nine (4–25) was reported and three (14%) patients suffered from daytime incontinence. No patients had symptomatic or endoscopic pouchitis; however, the histology showed unspecific inflammation in 19 (90%) patients. There was no correlation between transit time, evacuation fraction (EF) and pouch function in univariate analysis. However, we found a high body mass index (BMI) and a low bowel movement frequency to be associated with a longer transit time by multivariate analysis. Scintigraphic determination of transit time and defaecography are feasible methods in patients with ileal pouch anal anastomosis, but the clinical relevance is yet doubtful.
Mineralization of Early Stage Carious Lesions In Vitro—A Quantitative Approach
Authors: Deyhle Hans , Dziadowiec Iwona , Kind Lucy , Thalmann Peter , Schulz Georg , Müller Bert
Published: October 2015

Micro computed tomography has been combined with dedicated data analysis for the in vitro quantification of sub-surface enamel lesion mineralization. Two artificial white spot lesions, generated on a human molar crown in vitro, were examined. One lesion was treated with a self-assembling peptide intended to trigger nucleation of hydroxyapatite crystals. We non-destructively determined the local X-ray attenuation within the specimens before and after treatment. The three-dimensional data was rigidly registered. Three interpolation methods, i.e., nearest neighbor, tri-linear, and tri-cubic interpolation were evaluated. The mineralization of the affected regions was quantified via joint histogram analysis, i.e., a voxel-by-voxel comparison of the tomography data before and after mineralization. After ten days incubation, the mean mineralization coefficient reached 35.5% for the peptide-treated specimen compared to 11.5% for the control. This pilot study does not give any evidence for the efficacy of peptide treatment nor allows estimating the necessary number of specimens to achieve significance, but shows a sound methodological approach on the basis of the joint histogram analysis.
Energy Management of a Hybrid-Power Gas Engine-Driven Heat Pump
Authors: Meng Qingkun , Cai Liang , Ji Wenxiu , Yan Jie , Zhang Tao , Zhang Xiaosong
Published: October 2015

The hybrid-power gas engine-driven heat pump (HPGHP) combines hybrid power technology with a gas engine heat pump. The engine in the power system is capable of operating constantly with high thermal efficiency and low emissions during different operating modes. In this paper, the mathematical models of various components is established, including the engine thermal efficiency map and the motor efficiency map. The comprehensive charging/discharging efficiency model and energy management optimization strategy model which is proposed to maximize the efficiency of instantaneous HPGHP system are established. Then, different charging/discharging torque limits are obtained. Finally, a novel gas engine economical zone control strategy which combined with the SOC of battery in real time is put forward. The main operating parameters of HPGHP system under energy management are simulated by Matlab/Simulink and validated by experimental data, such as engine and motor operating torque, fuel consumption rate and comprehensive efficiency, etc. The results show that during 3600 s’ run-time, the SOC value of battery packs varies between 0.58 and 0.705, the fuel consumption rate reaches minimum values of approximately 291.3 g/(kW h) when the compressor speed is nearly 1550 rpm in mode D, the engine thermal efficiency and comprehensive efficiency reach maximum values of approximately 0.2727 and 0.2648 when the compressor speed is 1575 rpm and 1475 rpm, respectively, in mode D. In general, the motor efficiency can be maintained above 0.85 in either mode.
A Tabu Search Algorithm for the Power System Islanding Problem
Authors: Tang Fei , Zhou Huizhi , Wu Qinghua , Qin Hu , Jia Jun , Guo Ke
Published: October 2015

The power system islanding problem aims to divide the power system into several different islands after serious disturbances occur. The objective of this problem is to minimize the total generation-load imbalance of all islands while placing the coherent generators in the same island and maintaining the connectivity of each island. Two main challenges of solving this problem are the large scale of the power system and the requirement of a short computation time. In this study, we propose a tailored tabu search algorithm to solve this problem, which employs a novel initial solution generation procedure and a neighborhood operation based on the movement of the boundary nodes. The numerical experiments on 15 test instances show that this algorithm can deal with the power systems with up to 3120 nodes within 0.7 s. Then, the comparisons with some existing islanding methods based on the IEEE 39-bus system and the IEEE 118-bus system prove the validity and accuracy of our method. Finally, time-domain simulations based on three power systems demonstrate the importance of our tabu search algorithm in minimizing the impacts of the disastrous disturbances. The computational results imply that our tabu search algorithm is very effective and efficient and satisfies the requirements of islanding power systems of various sizes.
Analysis and Optimization Design of a Solar Water Heating System Based on Life Cycle Cost Using a Genetic Algorithm
Authors: Ko Myeong
Published: October 2015

This paper presents an optimization method to design a solar water heating (SWH) system based on life cycle cost (LCC). A genetic algorithm is employed to optimize its configuration and sizing as the optimization technique. To ensure that the optimal solution obtained from the proposed method is a practical design, three constraint conditions, including the energy balance, solar fraction, and available space to install solar collectors, have been set. In addition, the real devices available in the marketplace are considered in the optimization process that searches for optimal configuration and sizing, which is represented by the type and number of each component. By using the proposed method, a SWH system in an office building, South Korea has been designed and optimized. It is observed that a low solar fraction does not always present a decrease in the LCC. A trade-off between the equipment cost and the energy cost results in an optimal design of the SWH system that yields the minimum LCC.
A Multi-Criteria Decision Analysis of Waste Treatment Options for Food and Biodegradable Waste Management in Japan
Authors: Babalola Micky A.
Published: October 2015

Dealing with large-scale Food and Biodegradable Waste (FBW) often results in many logistical problems and environmental impacts to be considered. These can become great hindrances when the integration of solid waste management is concerned. Extra care is needed to plan such waste disposal or treatment services and facilities, especially with respect to the ecological impact. Decision-making with regards to the sustainable use of these facilities also involves tradeoffs between a number of conflicting objectives, since increasing one benefit may decrease the others. In this study a Multi-Criteria Decision Analysis (MCDA) is presented to evaluate different waste management options and their applicability in Japan. The analytical process aims at selecting the most suitable waste treatment option, using pairwise comparisons conducted within a decision hierarchy that was developed through the Analytical Hierarchy Process (AHP). The results of this study show that anaerobic digestion should be chosen as the best FBW treatment option with regards to resource recovery. The study also presents some conditions and recommendations that can enhance the suitability of other options like incineration and composting.
Nanoparticle-Integrated Hydrogels as Multifunctional Composite Materials for Biomedical Applications
Authors: Biondi Marco , Borzacchiello Assunta , Mayol Laura , Ambrosio Luigi
Published: October 2015

This review focuses on the most recent developments in the field of nanocomposite hydrogels intended for biomedical applications. Nanocomposite hydrogels are hydrated polymeric networks with a physically or covalently crosslinked three-dimensional (3D) structure swollen with water, in the presence of nanoparticles or nanostructures. A wide array of nanomaterials (polymeric, carbon-based, metallic, ceramic) can be incorporated within the hydrogel network to obtain reinforced nanocomposite hydrogels. Nanocomposites represent a new class of materials with properties absent in the individual components. In particular, the incorporation of nanomaterials within a polymeric hydrogel network is an attractive approach to tailor the mechanical properties of the hydrogels and/or to provide the nanocomposite with responsiveness to external stimuli.
Late Tertiary Petrified Wood from Nevada, USA: Evidence of Multiple Silicification Pathways
Authors: Mustoe George
Published: October 2015

Late Tertiary fossil woods from the state of Nevada provide an opportunity for observing the mineralization sequences that cause buried wood to become permineralized. Oligocene and Miocene caldera basins contain abundant petrified wood that ranges in composition from incipient silicification to complete permineralization. Examination of specimens from 21 localities reveals that the petrifaction sequence can follow multiple pathways. Fossil wood specimens from a single stratum may have different mineralization; silicification may vary even within a single specimen. Despite these variations, several trends are evident. Features in Nevada specimens suggest that two fundamental processes are involved: early mineralization of cell walls, and later silica deposition in lumina, vessels, and rot pockets from groundwater that permeated these open spaces. The process of open-space filling may be analogous to the genesis of geodes and veins, where multiple episodes of hydrothermal precipitation may produce opal, chalcedony, and quartz as deposits within a single cavity. Silica polymorphs may coexist as primary precipitates, or they may originate from solid-state transformation of a single parent material. Relic lepisphere textures observed in some chalcedony wood specimens are evidence of opal→chalcedony transition. In Nevada, specimens that contain crystalline quartz, this mineral appears to have been formed by direct precipitation in open spaces, not from recrystallization of chalcedony. Opal-A has seldom been reported in fossil wood, but this amorphous material is fairly common in Nevada specimens.
Prevalence and Molecular Characteristics of Waterborne Pathogen Legionella in Industrial Cooling Tower Environments
Authors: Li Lijie , Qin Tian , Li Yun , Zhou Haijian , Song Hongmei , Ren Hongyu , Li Liping , Li Yongguang , Zhao Dong
Published: October 2015

Cooling towers are a source of Legionnaires’ disease. It is important from a public health perspective to survey industrial cooling towers for the presence of Legionella. Prospective surveillance of the extent of Legionella pollution was conducted at factories in Shijiazhuang, China between March 2011 and September 2012. Overall, 35.7% of 255 industrial cooling tower water samples showed Legionella-positive, and their concentrations ranged from 100 Colony-Forming Units (CFU)/liter to 88,000 CFU/liter, with an average concentration of 9100 CFU/liter. A total of 121 isolates were obtained. All isolates were L. pneumophila, and the isolated serogroups included serogroups 1 (68 isolates, 56.2%), 6 (25, 20.7%), 5 (12, 9.9%), 8 (8, 6.6%), 3 (6, 5.0%) and 9 (2, 1.6%). All 121 isolates were analyzed by pulsed-field gel electrophoresis (PFGE) and 64 different patterns were obtained. All 121 isolates were analyzed sequence-based typing (SBT), a full 7-allele profile was obtained from 117 isolates. One hundred and seventeen isolates were divided into 49 sequence types. Two virulence genes, lvh and rtxA, are analyzed by polymerase chain reaction (PCR). 92.6% (112/121) and 98.3% (119/121) isolates carried lvh and rtxA respectively and 90.9% (110/121) of tested isolates carried both genes. Our results demonstrated high prevalence and genetic polymorphism of L. pneumophila in industrial cooling tower environments in Shijiazhang, China, and the SBT and virulence gene PCR results suggested that the isolates were pathogenic. Improved control and prevention strategies are urgently needed.
Lower Risk of Stroke after Deformity Surgery: Long Term Benefit Demonstrated by a National Cohort Study
Authors: Huang Liang-Chung , Chung Wu-Fu , Liu Shih-Wei , Chang Peng-Yuan , Chen Li-Fu , Wu Jau-Ching , Chen Yu-Chun , Huang Wen-Cheng , Liu Laura , Cheng Henrich , Lo Su-Shun
Published: October 2015

Objectives: This study aimed to investigate the long-term risk of stroke in adult patients with spinal deformity. Specifically, the study addressed the possible protective effect of surgery for spinal deformity against stroke. Methods: Using the National Health Insurance Research Database (NHIRD), a monopolistic national database in Taiwan, this retrospective cohort study analyzed the incidence of stroke in patients with adult spinal deformity (ASD) in a 11-year period. A total of 13,503 patients, between 55 and 75 years old, were identified for the diagnosis of ASD. The patients were grouped into two: the surgical group (n = 10,439) who received spinal fusion surgery, and the control group (n = 2124) who received other medical treatment. The incidence rates of all subsequent cerebrovascular accidents, including ischemic and hemorrhagic strokes, were calculated. Hazard ratios for stroke were calculated use a full cohort and a propensity score matched cohort. Adjustments for co-morbidities that may predispose to stroke, including hypertension, diabetes mellitus, arrhythmia and coronary heart disease were conducted. Kaplan-Meier and Cox regression analyses were performed to compare the risk of stroke between the two groups. Results: During the total observation period of 50,450 person-years, the incidence rate of stroke in the surgical group (15.55 per 1000 person-years) was significantly lower than that of the control group (20.89 per 1000 person-years, p < 0.001). Stroke was more likely to occur in the control group than in the surgical group (crude hazard ratio 1.34, p < 0.001; adjusted HR 1.28, p < 0.001, by a propensity score matched model). Conclusions: In this national cohort of more than 13,000 ASD patients covering 10 years, stroke was approximately 25% less likely to happen in patients who underwent spinal fusion surgery than those who received medical management. Therefore, spinal fusion surgery may provide a protective effect against stroke in adult patients with spinal deformity.
Hepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice
Authors: Li Jinlong , Duan Xiaoxu , Dong Dandan , Zhang Yang , Li Wei , Zhao Lu , Nie Huifang , Sun Guifan , Li Bing
Published: October 2015

Inorganic arsenic (iAs), a proven human carcinogen, damages biological systems through multiple mechanisms, one of them being reactive oxygen species (ROS) production. NRF2 is a redox-sensitive transcription factor that positively regulates the genes of encoding antioxidant and detoxification enzymes to neutralize ROS. Although NRF2 pathway activation by iAs has been reported in various cell types, however, the experimental data in vivo are very limited and not fully elucidated in humans. The present investigation aimed to explore the hepatic and nephric NRF2 pathway upregulation in acute arsenic-exposed mice in vivo. Our results showed 10 mg/kg NaAsO2 elevated the NRF2 protein and increased the transcription of Nrf2 mRNA, as well as up-regulated NRF2 downstream targets HO-1, GST and GCLC time- and dose-dependently both in the liver and kidney. Acute NaAsO2 exposure also resulted in obvious imbalance of oxidative redox status represented by the increase of GSH and MDA, and the decrease of T-AOC. The present investigation reveals that hepatic and nephric NRF2 pathway expression is an early antioxidant defensive response upon iAs exposure. A better knowledge about the NRF2 pathway involvment in the cellular response against arsenic could help improve the strategies for reducing the cellular toxicity related to this metalloid.
Identification of Risk Factors Affecting Impaired Fasting Glucose and Diabetes in Adult Patients from Northeast China
Authors: Yin Yutian , Han Weiqing , Wang Yuhan , Zhang Yue , Wu Shili , Zhang Huiping , Jiang Lingling , Wang Rui , Zhang Peng , Yu Yaqin , Li Bo
Published: October 2015

Background: Besides genetic factors, the occurrence of diabetes is influenced by lifestyles and environmental factors as well as trace elements in diet materials. Subjects with impaired fasting glucose (IFG) have an increased risk of developing diabetes mellitus (DM). This study aimed to explore risk factors affecting IFG and diabetes in patients from Northeast China. Methods: A population-based, cross-sectional survey of chronic diseases and related risk factors was conducted in Jilin Province of Northeast China. All adult residents, aged 18–79, were invited to participate in this survey using the method of multistage stratified random cluster sampling. One hundred thirty-four patients with IFG or DM and 391 healthy control subjects were recruited. We compared demographic factors, body size measurements, healthy-related behaviors, and hair metallic element contents between IFG/diabetes patients and healthy individuals. Results: IFG/diabetes patients had a greater weight, waist, hip, and body mass index (BMI) than control subjects. Significant differences in the content of zinc (Zn), potassium (K), copper (Ca), and sodium (Na) as well as Cu/Zn ratios between IFG or DM patients and control subjects (p < 0.05) were also observed. Hair Cu, selenium (Se), and Na contents were positively correlated with blood glucose levels (Cu: rs = 0.135, p = 0.002; Se: rs = 0.110, p = 0.012; Na: rs = 0.091, p = 0.038). Polytomous logistic regression adjusting for age, sex, family history of diabetes and BMI, showed that subjects with high BMI were more likely to develop IFG and DM (IFG: OR = 1.15, OR 95% CI = 1.02–1.29; DM: OR = 1.15, OR 95% CI = 1.01–1.33). Moreover, rarely or never eating fruits was a risk factor for DM (OR = 5.46, OR 95% CI = 1.87–15.98) but not for IFG (OR = 1.70, OR 95% CI = 0.72–4.02). Subjects with abdominal obesity or DM history were more susceptible to DM (abdominal obesity: OR = 2.99, OR 95% CI = 1.07–8.37; DM history: OR = 2.69, OR 95% CI = 1.01–7.20). We found that subjects living in Changling County had a significantly lower chance to suffer from IFG (OR and 95% CI for OR: 0.25, 0.08–0.74). Men and 60–69 years old subjects were at increased risk for IFG (male: OR = 3.51, OR 95% CI = 1.34–9.18; age 60–69: OR = 6.64, OR 95% CI = 1.36–32.47). We did not find significant associations of IFG or DM with certain lifestyles (such as eating more meat, exercise or physical activity, smoking, or alcohol drinking) or the content of some metallic elements (such as iron (Fe), Zn , K, calcium (Ca), Na, or magnesium (Mg)). Conclusions: This study demonstrated that less or no fruit eating, DM family history, abdominal obesity conferred vulnerability to DM. Living in Changling County, men and 60–69 years old subjects were found to be risk factors for IFG. Subjects with high BMI were more likely to develop IFG and DM.
Exploring Ecosystems and Health by Shifting to a Regional Focus: Perspectives from the Oceania EcoHealth Chapter
Authors: Kingsley Jonathan , Patrick Rebecca , Horwitz Pierre , Parkes Margot , Jenkins Aaron , Massy Charles , Henderson-Wilson Claire , Arabena Kerry
Published: October 2015

This article highlights contributions that can be made to the public health field by incorporating “ecosystem approaches to health” to tackle future environmental and health challenges at a regional level. This qualitative research reviews attitudes and understandings of the relationship between public health and the environment and the priorities, aspirations and challenges of a newly established group (the Oceania EcoHealth Chapter) who are attempting to promote these principles. Ten semi-structured interviews with Oceania EcoHealth Chapter members highlighted the important role such groups can play in informing organisations working in the Oceania region to improve both public health and environmental outcomes simultaneously. Participants of this study emphasise the need to elevate Indigenous knowledge in Oceania and the role regional groups play in this regard. They also emphasis that regional advocacy and ecosystem approaches to health could bypass silos in knowledge and disciplinary divides, with groups like the Oceania EcoHealth Chapter acting as a mechanism for knowledge exchange, engagement, and action at a regional level with its ability to bridge the gap between environmental stewardship and public health.
Writing in a Digital World: Self-Correction While Typing in Younger and Older Adults
Authors: Kalman Yoram , Kavé Gitit , Umanski Daniil
Published: October 2015

This study examined how younger and older adults approach simple and complex computerized writing tasks. Nineteen younger adults (age range 21–31, mean age 26.1) and 19 older adults (age range 65–83, mean age 72.1) participated in the study. Typing speed, quantitative measures of outcome and process, and self-corrections were recorded. Younger adults spent a lower share of their time on actual typing, and demonstrated more prevalent use of delete keys than did older adults. Within the older group, there was no correlation between the total time spent on the entire task and the number of corrections, but increased typing speed was related to more errors. The results suggest that the approach to the task was different across age groups, either because of age or because of cohort effects. We discuss the interplay of speed and accuracy with regard to digital writing, and its implications for the design of human-computer interactions.
Noise Effects on Health in the Context of Air Pollution Exposure
Authors: Stansfeld Stephen
Published: October 2015

For public health policy and planning it is important to understand the relative contribution of environmental noise on health compared to other environmental stressors. Air pollution is the primary environmental stressor in relation to cardiovascular morbidity and mortality. This paper reports a narrative review of studies in which the associations of both environmental noise and air pollution with health have been examined. Studies of hypertension, myocardial infarction, stroke, mortality and cognitive outcomes were included. Results suggest independent effects of environmental noise from road traffic, aircraft and, with fewer studies, railway noise on cardiovascular outcomes after adjustment for air pollution. Comparative burden of disease studies demonstrate that air pollution is the primary environmental cause of disability adjusted life years lost (DALYs). Environmental noise is ranked second in terms of DALYs in Europe and the DALYs attributed to noise were more than those attributed to lead, ozone and dioxins. In conclusion, in planning and health impact assessment environmental noise should be considered an independent contributor to health risk which has a separate and substantial role in ill-health separate to that of air pollution.