bluuebunny/crossref_metadata_2025 huggingface dataset:
Carino: homo omnium contaminatissimus o bene agens erga Christianos
Authors: Motta Daniela
Published: September 2024

S. Mazzarino leggeva l’ostilità della Historia Augusta verso Carino in parallelo all’attestazione della Passio Cantiorum relativa al cristianesimo dell’imperatore, interpretando i due testi come riflesso della rivalità fra il gruppo paganeggiante dei Nicomachi–Simmachi e quello cristiano dei Probi–Anicii agli inizi del V secolo. Tuttavia, la datazione più tarda della Passio, evidenziata in studi successivi, esclude una concomitanza cronologica fra i due testi. A partire da tali premesse, in questo saggio viene riesaminata nel suo complesso la tradizione storiografica e agiografica su Carino. In particolare, sul versante storiografico il raffronto fra filone greco, con specifico riguardo a Eunapio di Sardi, e filone latino, fa emergere come la rappresentazione deformante di Carino accomuni questi testi e affondi le sue radici nella propaganda dioclezianea. L’apporto della tradizione agiografica, che capovolge lo stereotipo negativo di Carino facendone un cristiano, si inserisce in questo quadro di analisi ed è a sua volta da leggere nella prospettiva della contrapposizione a Diocleziano. Accanto alla Passio Cantiorum vengono ripercorse altre testimonianze agiografiche relative a Carino cristiano, la Passio Sebastiani e il dossier sui SS. Cosma e Damiano; da un filone sui santi anargiri attinge Malala, il quale dunque segue la tradizione agiografica piuttosto che quella storiografica su Carino.
Das Konzept des sozialen Friedens und seine Widersprüche: ein Beitrag zu Aristoteles’ argumentativer und historischer Glaubwürdigkeit
Authors: Dietze-Mager Gertrud
Published: September 2024

The present article studies Aristotle’s concept of social peace which presupposes a stable politeia based on homonoia between rich and poor, and the existence of a broad middle class. It discusses Aristotle’s analysis of these prerequisites and their disruption by the demagogues and the payments for public service to the polloi. In the process we discover serious contradictions which weaken Aristotle’s reasoning. In the light of external sources it also becomes evident that his information concerning important aspects is misleading, and that, furthermore, he seems to circumvent information which might weaken his attack on what he considers the radical democracy of his time. As a consequence, Aristotle’s reliability as a historical witness is questioned.
T. Quinctio Crispino Badius Campanus Hospes Erat: L’ultimo duello capuano (Liv. 25.18.4–13)
Authors: Todaro Giovanna
Published: September 2024

L’articolo analizza l’episodio relativo al duello svoltosi nel 212 a. C., prima della riconquista romana di Capua, fra i due cavalieri Badio e Crispino, Campano l’uno e Romano l’altro (Liv. 25.18.4–13). La vicenda è incentrata sul legame di hospitium esistente tra i contendenti e rifiutato pubblicamente dallo sfidante Badio prima del combattimento. Il motivo letterario della monomachia, per di più declinata secondo lo schema dell’arcaico duello fratricida, all’interno della terza decade sembra soprattutto veicolare un messaggio ideologico e politico. La doppia corrispondenza fra microconflitto e macroconflitto, fra legame personale ricusato e alleanza fra Stati infranta, contiene un messaggio identitario e nazionalistico conforme alla linea politica instaurata dal principato dopo le guerre civili.
Ch. 7. Autopsy from a Broken Monarchy: Trauma-based Readings from Cassius Dio’s Contemporary Rome
Authors: Madsen Jesper Majbom
Published: September 2024

Cassius Dio’s contemporary books are often held to be for historians a particularly useful part of his Roman History. As a senator in Rome, Dio was well placed to describe what he saw during a long career in Roman politics. Dio’s eyewitness reports bring us right into the middle of the action but his own personal investment in the affairs raise the question of reliability and accuracy. In this article I read Dio’s contemporary books as a trauma-based narrative, where Dio uses personally invested autopsy accounts to paint the picture of a political collapse that follows the death of Marcus Aurelius. In Dio’s narrative, Rome is falling apart at the hands of tyrannical emperors who humiliated, pursued, prosecuted, or murdered members of the political elite who for their part were gradually losing their moral compass. Dio criticises the emperor of his time but the scope seems bigger. By sharing his traumatic experience from Roman politics, Dio’s trauma-based narrative serves to mobilise sympathy for the senators and thus a united front against the emperor of the time and the form of reign they choose.
Published in Andrew G. Scott,, ed., Studies in Contemporary Historiography (HISTOS Supplement 15), p. 163-189.
Exchange
Authors: Porciani Leone , Joyce C. J.
Published: September 2024

This is an exchange between Leone Porciani (in Italian) and C. J. Joyce (in English).
Fate, Divine Phthonos, and the Wheel of Fortune: the Reception of Herodotean Theology in Early and Middle Byzantine Historiography
Authors: Zali Vasiliki
Published: September 2024

Herodotus enjoyed wide popularity among Byzantine historians. Within a Christian society, his complicated religious outlook and his moral viewpoint were of interest to the historians while at the same time presenting difficulties for their perception of historical causation. This article traces the responses of three early and middle Byzantine historians to Herodotus’ religious views. I focus in particular on the significance which three concepts central to Herodotus’ religious and historical thought—fate, divine phthonos, and the wheel of fortune— hold in selected passages from Procopius’ Wars, Michael Psellus’ Chronographia and Nicetas Choniates’ History. I argue that these three concepts are not merely employed as literary devices but can help elucidate the theological and historical views of the Byzantine historians.
Published in Anthony Ellis, ed., God in History (HISTOS Supplement 4), p. 85-126.
Ch. 4. Honour and the Art of Xenophontic Leadership
Authors: Keim Benjamin D.
Published: September 2024

Throughout his wide-ranging corpus Xenophon portrays the desire for honour as a fundamentally human characteristic, one commonly attributed to rulers and commanders and yet also found among other individuals, regardless of their sex or social status. Here I explore how the motivations of honour, and the award of instantiated honours, are to be negotiated by Xenophon’s ideal leader. Every leader is in a position of honour: in order to be successful the good leader must first establish, by properly honouring the gods and his followers, the context within which he may then distribute honours effectively, thereby helping train his followers and achieve their mutual flourishing.
Published in Richard Fernando Buxton, ed., Aspects of Leadership in Xenophon (HISTOS Supplement 5), p. 121-62.
VOLUME-SCULPTURAL RESTORATION MATERIALS FOR RESTORING THE APPEARANCE OF BIOLOGICAL OBJECTS DURING THEIR LONG-TERM PRESERVATION (REVIEW)
Authors: Abramov Yu.V.
Published: September 2024

The problem of finding restoration materials that have the necessary properties for their use on preserved biological objects still remains relevant in medicine (in particular, in forensic medicine, anatomy, thanatopraxy) and museums. This work summarizes information about materials used to eliminate volumetric defects in the appearance of biological objects, in particular, museum exhibits, anatomical preparations and bodies of the dead. Information has been collected on the composition of multicomponent plastics used in restoration. It has been established that various types of materials for the restoration of long-term preserved biological objects, as well as many technologies and techniques for their use, are largely taken from the field of makeup and cosmetology techniques. Natural polymers traditionally used in restoration continue to be widely used in restoration work on biological objects. These are plant, animal and mineral waxes, animal and vegetable glues, as well as natural resins. To create sculptural restoration elements, both homogeneous materials (for example, wax) and multicomponent plastic masses, consisting of several natural components with the addition of pigments, are used. Commercially available, ready-made restoration waxes are also used. Recently, various classes of synthetic polymers, such as polyethylene glycols, polyurethanes, epoxy resins, dental plastics, tetrafluoroethylene-based copolymers, silicones, synthetic latex and others, have become widely used in volumetric sculptural restoration. Separately, data on the restoration of objects from natural history collections of museums is summarized. In this area, completely different materials are used to eliminate volumetric defects in exhibits, often those that are more accessible and allow for rapid restoration of the appearance of a biological object. In the restoration of museum exhibits, cotton wool, paper, various sealants, mastics, putties, synthetic and natural polymers and many other materials are used
SELECTION AND EVALUATION OF CONSERVATION CONDITIONS OF CLAVICEPS PURPUREA SAPROPHYTIC LINES
Authors: Volnin A.A. , Bobyleva R.I. , Tsybulko N.S. , Savin P.S. , Shtrom K.A. , Myasnikova S.B. , Bokhan A.I.
Published: September 2024

Introduction. Ergot Claviceps purperea plays an important role in health-care technologies. Accumulation of genetic resources of industrial pharmaceutical strains of parasitic ergot is the actual scientific problem. This work is devoted to development of selection and evaluation of conservation conditions of Claviceps purpurea saprophytic lines. Conidiospores and saprophytic mycelium were frozen at –20 0C, after 10 months of storage and cultivated in Erlenmayer flasks on a liquid medium and on an agarised medium. Cryopreserved samples of conidiospores and mycelium retained the ability to grow and alkaloids biosynthesis in vitro. Results. The best lines were selected from sclerotias of 3 parasitic strains and deposited in the form of axenic and saprophytic mycelium for long-term storage (ergotoxin ВКМ-F-2450-D-23-1, ergotoxin ВКМ-F-2450-D-23-9, ergotamine ВКМ- F-2641-D-S-2, ergocornam ВКМ-F-3662-D-22-5). Sclerotia of ergotamine-producing strain had a level of alkaloid synthesis of 0.78 g/100 g, with an ergotamine content of 67.9%, and demonstrated of pigmented purple mycelium in axenic culture. Sclerotias of ergotoxin-producing strain – 0.76 and 0.59 g/100 g, containing 51.5 and 50.3% of the sum of ergocornine and α-ergocryptine, 20 and 22% of β-ergocryptine, respectively, both lines demonstrated sclerotia-like mycelium and alkaloids biosynthesis in saprophytic cultivation on agarised medium. Sclerotia of ergocornam-producing strain – 0.79 g/100 g, containing 18.2% of ergocornam and 24.6% of ergometrine, demonstrated pigmented purple mycelium in axenic culture. Conclusion. Development of long-term storage biocollections, including cryocollections for organisms producing pharmaceuticals raw substances, creates the basis for technological sovereignty of the Russian Federation. It is reducing dependence on imported drugs and pharmaceuticals raw substances, including ergoalkaloids.
SOME PLANT SECONDARY METABOLITES AS PROMISING CANDIDATES FOR THE TREATMENT OF LUNG CANCER AND PANCREATIC CANCER
Authors: Mezhevova I.V. , Filippova S.Yu. , Chembarova T.V. , Gnennaya N.V. , Zlatnik E.Yu. , Novikova I.A. , Enin Y.S. , Burov O.N.
Published: September 2024

Introdution. Cancer is the second leading cause of death in Russia and the world after cardiovascular diseases. Chemotherapy remains the main line of treatment, but tumor cells can become resistant to drugs. Researchers are working on new effective drugs, including secondary metabolites of plants that have antitumor effects through various mechanisms. The aim of this study was to investigate the cytotoxic properties of three compounds: alkaloid P1, terpenoid P2, and flavonoid V1 against pancreatic cancer cell line AsPC-1 and non-small cell lung cancer H1299. Material and methods. Secondary metabolites of Petasites hybrydicus (L.) G. Gaertn., B.Mey. & Scherb. and Viscum album L. were extracted using tetrachloroethylene. For identification of the isolated compounds, high-performance liquid chromatography with mass detection and nuclear magnetic resonance method were used. Non-small cell lung cancer cell line H1299 and pancreatic cancer AsPC-1 were grown in RPMI1640 medium (Gibco, USA) supplemented with 10% FBS (HyClone, USA) and 1% glutamine (Biolot, Russia) under standard conditions. Cell sensitivity to the studied compounds was determined by MTT test. Results. All three compounds demonstrated antitumor activity against the studied cell lines. Compound V1 increased signs of mesenchymal cells morphology and apoptosis, with IC50 values of 234.24±21.56 μM (AsPC-1) and 565.62±84.31 μM (H1299). Compound P1 promoted multinucleated cell formation in H1299 culture. Half-inhibitory doses for P1 were 652.54±56.12 μM (AsPC-1) and 157.85±48.62 μM (H1299). Compound P2 induces cell apoptosis and necrosis and probably affects membrane rigidity. The IC50 values for P2 were 802.34±121.02 μM (AsPC-1) and 415.71±75.05 μM (H1299). Conclusions. These compounds can be considered promising antitumor agents for lung cancer and pancreatic cancer.
S-NITROSOGLUTATIONIN AS AN INDUCER OF NITROSATIVE STRESS
AND APOPTOSIS
Authors: Suchkova O.N. , Abalenikhina Yu.V. , Shchulkin A.V. , Kostyukova E.V. , Kochanova P.D. , Gadzhieva F.T. , Yakusheva E.N. , Uzbekov M.G.
Published: September 2024

Introduction. S-nitrosoglutathione is an S-nitrosylated derivative of glutathione and is considered an important mediator of the signaling effects of ni-tric oxide (II). In turn, nitric oxide can exhibit both regulatory and toxic effects due to the formation of active forms of nitrogen and nitrosylation of in-tracellular components, which can lead to the development of apoptosis. The role of nitric oxide in the regulation of apoptosis is dual, and therefore re-quires further study. The aim of the work was to study the possibility of the development of nitrosative stress and apoptosis under the action of the NO donor – S-nitrosoglutathione. Material and methods. The study was performed on a HepG2 cell culture. S-nitrosoglutathione was added to the cells at concentrations of 1, 10, 50, 100 μМ and incubated for 3 and 24 hours. Water (S-nitrosoglutathione solvent) was added to the control cells in an equivalent volume. Photometric methods were used to determine cell viability (MTT test), the concentration of nitric oxide and peroxynitrite metabolites. Expression of 3-nitrothyrosine, Bcl2 and Fas were detected by Western blot. Results. S-nitrosoglutathione at a concentration of 100 μМ (24 h) decreased cell viability and increased concentration of peroxynitrite. The level of nitric oxide metabolites increased under the action of S-nitrosoglutathione at concentrations of 1–100 μМ and exposure periods of 3 and 24 hours, which led to an increase the expression of 3-nitrothyrosine. S-nitrosoglutathione with incubation for 3 hours and concentrations of 1–50 μM increased the level of Bcl2, at concentrations of 50–100 μM it decreased the content of Fas; when incubated for 24 hours and concentrations of 1-100 µM it decreased the level of Bcl2 and Fas. Conclusion. Thus, in this study, it was found that S-nitrosoglutathione at concentrations of 1–50 μM and an exposure period of 3 hours has a signaling effect in HepG2 cells. S-nitrosoglutathione at a concentration of 100 μМ during incubation of 3 and 24 hours causes the development of nitrosative stress, which leads to the development of apoptosis and decreased cell viability.
PKM UPAYA PENCEGAHAN MIS-INFORMASI DAN DISINFORMASI PADA PELAJAR SMP N 1 DI KOTA SALATIGA DALAM MELAWAN INFORMASI HOAK DI INTERNET
Authors: Triyono Agus , Suhariyanto Suhariyanto , Satria Candra Yuda , Adham Muhammad Afif Ridwan
Published: September 2024

Di beberapa platform media sosial saat sering terjadi unggahan atas pelanggaran yang dilakukan oleh sekelompok orang. Tak jarang konten berisikan tentang tindakan kriminal yang dilakukan oleh anak-anak yang masih remaja dengan status pelajar sekolah menengah pertama (SMP). Kejadian itu setelah ditangani pihak berwajib akibat dari pengaruh media sosial yang berisi konten misinformasi dan disinformasi.
Tujuan kegiatan ini dilakukan adalah untuk memberi pemahaman dan aksi nyata dengan meningkatkan skill dan penjelasan yang komprehensif untuk mengantisipasi tindakan negatif aktibat konsumsi internet.
Metode kegiatan dilakukan dengan memberikan paparan materi dan praktek langsung dalam penggunaan smartphone dalam mencegah timbulnya disinformasi dan misinformasi dari internet.
Hasil dari kegiatan ini adalah pelajar SMP kelas 8 mampu berpikir kritis atas masifnya informasi di internet di smart phonenya. Dari pola pikir kritis tersebut kemudian mampu mengambil sikap atas informasi yang diperoleh dengan cara cros cek melalui nalar sehat dan bantuan aplikasi untuk mampu mengambil kebutusan secara bijak. Dari hal tersebut pelajar sudah mendapat asupan informasi yang cukup dan membuat perubahan untuk bijak menggunakan smart phonenya.
Kesimpulan kegiatan ini adalah pelajar sudah kritis dan mampu memilah informasi yang benar atau yang mengandung unsur hoak. Sehingga pelajar dapat menggunakan internet untuk kebutuhan positif dan tidak terhasut provokasi atas informasi yang tidak bermanfaat.
PEMBERDAYAAN PETANI KELAPA SAWIT DI DESA TIANG TARA MELALUI PELATIHAN GOOD AGRICULTURAL PRACTICES
Authors: Bahtera Novyandra Ilham , Yulia Yulia , Herza Herza
Published: September 2024

Desa Tiang Tara di Kecamatan Bakam, Kabupaten Bangka, memiliki luas wilayah 4.954 hektar dengan 61,6% digunakan untuk perkebunan kelapa sawit. Desa ini menghadapi berbagai tantangan dalam sektor pertanian, terutama bagi petani kecil kelapa sawit yang mengalami kesulitan bersaing di pasar internasional, kurang memahami Good Agricultural Practices (GAP), dan menghadapi rantai pasok yang panjang. Selain itu, petani kecil juga terhambat oleh kondisi sosial-ekonomi yang rendah, akses terbatas ke teknologi, dan kurangnya pengetahuan pertanian. Program pemberdayaan ini bertujuan untuk meningkatkan pengetahuan dan keterampilan petani melalui sosialisasi, pelatihan, dan pendampingan dalam penerapan GAP. Target dari program ini meliputi peningkatan pengetahuan GAP dan adopsi praktik GAP oleh petani. Metode pelaksanaan program mencakup kerjasama dengan berbagai pihak, sosialisasi, pelatihan intensif, dan pendampingan teknis. Evaluasi dilakukan melalui kuesioner untuk mengukur keberhasilan program serta memperoleh umpan balik dari peserta. Hasil penelitian menunjukkan bahwa mayoritas petani berusia di atas 40 tahun dengan pendidikan formal rendah, yang mempengaruhi pemahaman mereka terhadap GAP. Saat ini, produksi rata-rata kelapa sawit masih rendah dan pendapatan petani belum mencukupi. Melalui program ini, pengetahuan dan keterampilan petani dalam budidaya kelapa sawit meningkat, yang diharapkan dapat meningkatkan produktivitas dan kesejahteraan petani di Desa Tiang Tara.
Incorporação da Mercaptopurina em sistemas multicamadas
Authors: Souza Vitor Oliveira De , Ribeiro Raquel , Almeida Ester Costa de , Abrahão João Marcos Pinheiro Moreira , Letichevsky Sonia , Silva Cristiane Evelise Ribeiro da , Sousa Filho Idio Alves de , Sales Tiago José Bandeira , Gomes Vinicius Olivieri Rodrigues , Mendonça Roberta Helena
Published: September 2024

O câncer continua sendo uma doença desafiadora, exigindo esforços contínuos para explorar estratégias inovadoras de tratamento. O desenvolvimento de sistemas de entrega de medicamentos (DDS) utilizand
A PANDEMIA E O RISCO DE MEDICALIZAÇÃO DA VIDA
Authors: Silva Jéssica Pacheco Da , Batista Larissa de Oliveira de , Tuon Lisiane , Ceretta Luciane BISOGNIN
Published: September 2024

A medicalização é uma prática realizada pela medicina que implica na vida das pessoas de forma adequada para o processo de tratamento das doenças das mesmas. Porém, a população diante enfrentamento do
COMO DEVO CUIDAR DO MEU CATETER DE HEMODIÁLISE?
Authors: Sousa Ralrizônia Fernandes , Carneiro Irna Carla do Rosário Souza , Santos Valéria Regina Cavalcante dos , Viana Danielle Rachid , Santos Jackson
Published: September 2024

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Emergent Technologies in Human Detection for Disaster Response: A Critical Review
Authors: Ahmed Sajjad
Published: September 2024

In the face of natural disasters, the rapid detection of trapped victims is crucial for effective search and rescue (SAR) operations. This review critically examines the emergent technologies in human detection that are pivotal in disaster response. Current methodologies for human detection encompass a variety of techniques: Radar, Artificial intelligence (AI), Drones, Robotics, Gas sensors, Acoustic, Infrared, and Optical detection. These methods are specifically designed to detect human presence in disaster scenarios by leveraging principles from electromagnetic, acoustic, AI-based algorithms, gas sensors, and optical detection. However, these technologies face challenges and limitations. They often depend on environmental conditions, encounter obstacles that affect their penetration capabilities, and have limited spatial resolution due to complex backgrounds. This paper aims to provide a comprehensive overview of the state-of-the-art in human-detection technologies, assess their impact on SAR missions, and offer insights into future advancements that could further enhance the survivability of disaster-stricken individuals.
Importancia de las variaciones anatómicas en la educación en salud
Authors: García Sarria Laura , Restrepo Laura , Montoya Cobo Estefania
Published: September 2024

Introduction: Anatomical variations constitute an area that has been little addressed in the different study plans of careers such as Medicine and Nursing, since they are exclusively associated with medical-surgical specialties, however, their knowledge must be present from clinical suspicion and improve diagnosis and treatment times. In all surgeries there is a 15% risk of complications and even death, associated with ignorance of the different anatomical variations present in humans, making professional performance difficult.
Materials and methods: A review of the topic was carried out using PubMed with keywords and an advanced search equation. 83 articles were returned, of which 48 that did not meet the objective of the study were discarded, finally reviewing 35 documents.
Results: In the cardiovascular, nervous and muscular systems there is a wide range of anatomical variations that are little known or applied in clinical correlation, especially cardiovascular, nervous and muscular.
Discussion: Although not all reports on anatomical variations present a high percentage, it is necessary for the health professional to know and recognize the risks that their presence can cause in the patient.
Conclusions: Despite the few percentages of variability reported in different body systems, its identification from undergraduate careers in the health area is essential, in order to improve the diagnosis-treatment correlation and surgical planning with a reduction in associated complications. due to lack of knowledge of unconventional anatomy
Concurrent Guillain-Barré syndrome and longitudinally extensive myelopathy secondary to SARS-CoV-2 infection. Case report
Authors: Bonilla Arbelaéz Maria Isabella , Clavijo Salazar D’angelo , Cruz López Juan Felipe , Duque Montoya Daniela
Published: September 2024

Introduction: The severe acute respiratory syndrome caused by the virus SARS-CoV-2 may have a wide range of neurological manifestations. Guillain-Barré syndrome (GBS) is a post-infectious acute polyneuropathy characterized by symmetrical and ascending flaccid paralysis, described as a complication of SARS-CoV-2 infection and other pathogens. Inflammatory myelopathies associated with the virus have been also described, among which transverse myelitis is frequent. Outstanding the autoinflammatory characteristics of both entities, there is the possibility of concurrent presentation.
Case description: a 23-year-old male consulted due to pain and ascending acute weakness syndrome in the lower limbs with the impossibility for urination and defecation over a 4-day course. The diagnosis of Guillain Barrè was made by electromyography, a thoracolumbar magnetic resonance was performed, with findings of longitudinally extensive inflammatory myelopathy. An antibody test for SARS-CoV-2 was performed on cerebrospinal fluid with a positive IgG result, considering neurological compromise because of the virus. Management was done with plasmapheresis and methylprednisolone pulses, with a favorable response and hospital discharge. 
Discussion: the compromise of SARS-CoV-2 in the central and peripheral nervous system is known. Pathologies such as Guillain Barrè syndrome have been widely reported and studied as a consequence of SARS-CoV-2 infection, also exist a variety of reports of longitudinally extensive inflammatory myelopathy associated with the pathogen, however, the concurrence between both pathologies has been scarcely reported.
Conclusions: It is necessary to consider the wide variety of atypical presentations, and even confluent ones, caused by infectious agents such as SARS-CoV-2, to achieve timely diagnosis and management that reduce morbidity and mortality in patients.
Prevalencia y características clínicas de pacientes con diagnóstico de agujero macular idiopático en un hospital de tercer nivel del noroeste de México
Authors: Lugo Machado Juan Antonio , Rodríguez Pérez Ricardo , Suarez Argüello Javier
Published: September 2024

INTRODUCCIÓN: El agujero macular (AM) es un defecto retiniano circular en el área foveal de la retina neurosensorial, puede ser de espesor completo (AMEC) o lamelar cuando el defecto no involucra todas las capas de la retina neurosensorial.
OBJETIVO. Determinar la prevalencia de agujero macular idiopático en el Hospital de especialidades 2 del IMSS Cd Obregón Sonora.
MATERIAL Y MÉTODOS. Estudio retrospectivo, transversal, observacional, descriptivo, selección no probabilística de casos consecutivos de la consulta evaluados de primera vez con la tomografía de coherencia óptica RTVue XR/CAM y se diagnosticó con agujero macular idiopático, tomaron las variables clínicas y demográficas. Se empleó estadística descriptiva, usamos Ji cuadrado de bondad de ajuste para contrastar la prevalencia, consideramos diferencias significativas un valor de p≤0.05, empleamos SPSS versión 24.
RESULTADOS.
Se encontró una prevalencia de 3.2%, edad promedio 68.72DS±8.736, femenino 22 (61.1%) el tamaño media 485.00 DS ± 270.302, el sexo femenino 22 (61.1%) ojos izquierdos 55.5% , agudeza visual  20/60 o peor fueron 88.9%,  la hipertensión arterial  36.1%, estadificación  de Gass  fue en 61.1% estadios 4, de las enfermedades concomitantes 25% presentó alguna, y  glaucoma fue  13,9% , la mayoría 58.3%) fue manejado con vitrectomía.
CONCLUSIÓN.  La prevalencia de agujero macular idiopático, es similar lo reportado a nivel nacional, sin embargo, es mayor a lo descrito por otros autores a nivel internacional, edad en la séptima década de la vida y sexo femenino. son las características clínicas que presentan los casos de agujero macular idiopático en nuestro nosocomio.
Actividad física y salud mental en estudiantes universitarios de la ciudad de Bogotá - Colombia durante el tiempo de pandemia por COVID-19.
Authors: Caranton Pineda Felipe Antonio
Published: September 2024

Introducción: La interacción entre los bajos niveles de actividad física y los problemas de salud mental se acentuaron en el tiempo de pandemia por COVID-19 en los estudiantes universitarios, por lo que, es necesario realizar la medición y el análisis de la relación de estos factores para establecer un punto de partida en el planteamiento de estrategias de intervención.
Objetivo: Analizar el nivel de práctica de actividad física en la comunidad de estudiantes de pregrado de la Fundación Universitaria de Ciencias de la Salud (FUCS) y su relación con el estado de salud mental durante el tiempo de pandemia por COVID-19.
Métodos: Estudio de tipo descriptivo transversal. Muestreo no probabilístico de 389 estudiantes de los programas de Fisioterapia y Psicología. Los niveles de actividad física se evaluaron con el Cuestionario Internacional de Actividad Física (IPAQ-SF), y para el estado de salud mental se utilizó la Escala de Medición de Depresión, Ansiedad y Estrés (DASS-21). Los resultados se presentan por medio de medidas de tendencia central, de dispersión y correlaciones estadísticas.
Resultados: Se realizaron un total de 389 mediciones, entre estudiantes de Fisioterapia (64%) y Psicología (36%). El nivel de práctica de actividad física fue de alta intensidad (9.4%), moderada intensidad (54,4%) y baja intensidad (36.6%). En los resultados de salud mental, el nivel de estrés se presentó en el 66.9%, depresión en el 64% y ansiedad en el 75% de los encuestados. La correlación de Spearman más negativa (-0.106) se obtuvo entre días de actividad física moderada y ansiedad.
Conclusiones: Diferentes investigaciones han reportado que la práctica de actividad física disminuye los problemas de salud mental, sin embargo, lo encontrado en esta investigación sugiere que solamente la práctica de actividad física intensa (días y minutos por semana) y moderada (días por semana) parecen disminuir los niveles de ansiedad, estrés y depresión. Los resultados no son significativos, por lo que se sugiere ampliar la investigación a otras facultades, para obtener cifras que promuevan la implementación de programas que disminuyan las alteraciones en la salud mental utilizando la práctica de actividad física como factor protector.
Relación entre las características de los recién nacidos sometidos a procedimientos dolorosos no-quirúrgicos y el manejo del dolor en una unidad de cuidado neonatal de Manizales, Colombia.
Authors: Malaver Diaz Manuel Teodolfo
Published: September 2024

Introduction: The development of new technologies for early diagnosis and treatments has allowed, in recent decades, an increase in the survival of newborns, especially the premature. However, the requirement for recurrent invasive examinations and procedures that generate pain is also increasing. Despite the evidence of the implications of pain on the development of the newborn and in the subsequent phases of life, strategies aimed at pain control are not sufficient and the variability in its management remains significant.
 
Objectives: To evaluate pain management in neonates undergoing minor procedures in a neonatal care unit.
 
Methods: Retrospective study with an analytical purpose.
 
Results: An average of 13.6 painful procedures for each newborn, in addition to extensive use of glucometry even outside the highest risk groups, without any type of analgesia, like majority of subjects subjected to punctures. vascular and vaccination. Procedures such as PICC, lumbar punctures, and bladder catheterizations showed uneven application of analgesia, with only 21% of PICC and 15% of lumbar punctures receiving adequate analgesia, while bladder catheterizations received better management at 60%. of analgesic coverage.The most used form of analgesia is non-pharmacological, for most procedures.
Conclusions: This study concludes that there is an urgent need to standardize and improve pain management practices in neonates, to ensure more consistent and evidence-based care.
Biochemical and Molecular Identification of Azospirillum brasilense Bacteria and Evaluation of Their Efficiency in Producing Hormones, Dissolving Phosphorus, and Fixing Nitrogen
Authors: Jawad Naseer , Abdul Kadhim Kamal Jawad
Published: September 2024

The study aimed to isolate A.brasilense bacteria from the soil of the rhizosphere of different plants and different locations in Al-Diwaniyah Governorate. They were identified in two ways. The first was the routine method, which included studying the microscopic and cultural characteristics and biochemical tests of the isolates. The second method was molecular, using polymerase chain reaction (PCR) technology and using primers. It also included testing the efficiency of these isolates in dissolving tricalcium phosphate (TCP) on Pikovskaya agar medium, fixing nitrogen in the liquid nutrient medium (N.B), and measuring the amount of hormone production using an HPLC device. The results of isolation and regular and molecular identification the presence of ten isolates of bacteria bearing the characteristics of A. brasilense bacteria, out of fifteen local bacterial isolates, took the following symbols and sequences (Az2, Az3, Az5, Az6, Az7, Az9, Az11, Az12, Az13, Az14), as the results showed confirmation of the identification of the bacterial isolates identified by biochemical tests. Using a specialized primer to amplify the 462bp fragment of the 16S ribosomal RNA gene, the results of testing the efficiency of the bacteria in dissolving phosphate (TCP) showed that the isolate (Az13) outperformed the highest value in its effectiveness in dissolving metallic phosphorus through the diameter of the clear zone around the colony, which was effective in dissolving phosphate of up to 3.89 mm. As for the nitrogen fixation efficiency test, the isolate (Az3) excelled in the amount of fixed nitrogen reaching 12.44 mg.L-1. As for the amount of its production of growth regulators for Auxins, Gibberellins, and Cytokinins, the isolate (Az3) recorded the highest value in the amount of Auxins production ( Indol-3-acetic acid) its concentration reached 34.4 µg.ml-1, and as for the production of the hormone Gibberellins (GA3), the isolate (Az3) recorded the highest value amounting to 34.7 µg.ml-1, as for the production of the hormone Cytokinins (CK), The isolate (Az11) recorded the highest value, amounting to 28.8 µg.ml-1.
Clearview: Real-time traffic signal and license plate recognition
Authors: Abhishek Jadhav  , Mohan Aradhya
Published: September 2024

This paper introduces an exploratory innovative Android application called ‘Clearview’ to directly address a particular prerequisite needed in ITS, namely, real-time traffic light and license plate identification in situations that include adverse weather that include fogs and hazes. The Traffic Management System of Clearview involves impressive technologies used in traffic surveillance and managing incidences of traffic congestions. The core of the developed application entails the use of Generative Adversarial Networks GAN in dehazing aspect that makes it rather simple to improve clarity and image brightness particularly under poor visibility conditions. Thus, dehazed images were fed into YOLOv4, the real-time object detection model to get a better prediction of traffic signals on the road. To find the outline of the objects like a vehicle, Clearview utilizes single shot multiBox detector (SSD) while the characters in the license plate are identified with the help of Tesseract OCR. The developed application also schedules on-device inference through optimizing the deep- learning model with the TensorFlow Lite for boosting real-time responses. Using TensorFlow/Keras for deep learning, OpenCV for computer vision, and Android Studio for app development, Clearview is created to be a plug-and-play system on this basis where all of these technologies are integrated into one functioning system. The real life detection rates were presented after the evaluative experimentation of Clearview and supported by evidences that is possible to achieve over 90% of the detection rates while working on real time. The following paper attempts at outlining the structure and architecture of the system under consideration, the technologies utilized in the formulation of Clearview and the various performance indices that will qualify ITS technology and traffic observation under difficult conditions hence the overall role played by Clearview in advancement of ITS technology.
Integrating security, privacy, and advanced cyber technologies for Resilient Urban, IoT, and AI Systems
Authors: Ali Dayoub
Published: September 2024

This paper explores the critical intersection of cybersecurity, privacy, and advanced technologies in today's interconnected urban environments. It reviews recent advancements in secure communication, vehicle networks, and smart systems while addressing the growing challenges of cyber threats across domains such as healthcare, education, and infrastructure. By integrating innovative approaches, including machine learning, blockchain, and secure routing protocols, the paper emphasizes the importance of creating resilient systems that can safeguard data integrity, ensure privacy, and protect against malicious activities. The analysis also considers the potential of large language models and AI techniques to advance cybersecurity measures and highlights emerging strategies for defense against evolving threats in smart cities and beyond.
Large Language Models (LLMs) for Cybersecurity: A Systematic Review
Authors: Yazi Gholami
Published: September 2024

The rapid evolution of artificial intelligence (AI), particularly Large Language Models (LLMs) such as GPT-3 and BERT, has transformed various domains by enabling sophisticated natural language processing (NLP) tasks. In cybersecurity, the integration of LLMs presents promising new capabilities to address the growing complexity and scale of cyber threats. This paper provides a comprehensive review of the current research on the application of LLMs in cybersecurity. Leveraging a systematic literature review (SLR), it synthesizes key findings on how LLMs have been employed in tasks such as vulnerability detection, malware analysis, and phishing detection. The review highlights the advantages of LLMs, such as their ability to process unstructured data and automate complex tasks, while also addressing challenges related to scalability, false positives, and ethical concerns. By exploring domain-specific techniques and identifying limitations, this paper proposes future research directions aimed at enhancing the effectiveness of LLMs in cybersecurity. Key insights are offered to guide the continued development and application of LLMs in defending against evolving cyber threats.
Data-driven analytics and modelling of circular supply chains for net zero manufacturing
Authors: Chinedu C. Onyeje  , Adeyemi Zaheed Oshilalu  , Busola Fadojutimi
Published: September 2024

This study aims to explore the application of data-driven analytics and modelling, using Convolutional Neural Networks (CNN) and MATLAB, to develop circular supply chains that support net zero manufacturing. As industries face growing pressure to reduce their environmental impact, circular supply chains, which focus on resource reuse, waste reduction, and sustainable production, are becoming essential. By integrating CNN models for data analysis and optimization, this research enhances the ability to identify inefficiencies, forecast demand, and optimize resource flows, contributing to a reduction in carbon emissions. Key findings demonstrate that circular supply chain strategies, enhanced by CNN-driven analytics, significantly reduce carbon footprints in manufacturing processes. The application of CNN, executed in MATLAB, enables advanced pattern recognition for optimizing material reuse, predicting logistical demands, and improving lifecycle management. These data-driven insights result in lower emissions, cost savings, operational efficiencies, and enhanced supply chain resilience. The implications of these findings suggest a transformative impact on the manufacturing industry. By adopting CNN-based analytics powered through MATLAB for circular supply chains, companies can achieve net zero goals while improving competitiveness. This approach fosters a shift towards sustainable manufacturing by minimizing reliance on finite resources and reducing waste, aligning the industry with global sustainability objectives.
Nilai-Nilai Pendidikan Karakter dalam Buku Teks Pelajaran Bahasa Indonesia SMP Kelas VIII Kurikulum Merdeka
Authors: Kriswidyasari Vincencia Lucky , Sri Muryati  , Wahyu Dini Septiari
Published: September 2024

Penelitian ini bertujuan untuk mengetahui nilai-nilai karakter dan mendeskripsikannilai-nilai pendidikan karakter yang terdapat dalam buku teks Bahasa Indonesia kelas VIII SMP Kurikulum Merdeka dengan dimensi Profil Pelajar Pancasila. Penelitian ini merupakan jenis penelitian deskriptif kualitatif. Data dari penelitian ini adalah teks. Wujud dari data adalah frasa, kalimat, maupun kata yang mengandung nilai pendidikan karakter. Sumber data berasal dari buku teks pembelajaran Bahasa Indonesia SMP Kelas VIII Kurikulum Merdeka. Data yang didapatkan kemudian dianalisis sesuai dengan jenis-jenis karakter yang ada dan dikategorikan sesuai dengan keterampilan berbahasa. Penelitian ini dikategorikan sesuai dengan dimensi Profil Pelajar Pancasila. Perolehan data penelitian dibatasi dengan keterampilan berbahasa. Hasil penelitian ditemukan sebanyak 27 nilai karakter di dalam buku Bahasa Indonesia kelas VIII SMP Kurikulum Merdeka yang terdiri dari 4 nilai karakter beriman bertakwa kepada Tuhan YME dan berakhlak mulia; 1 nilai karakter berkebinekaan global; 4 nilai karakter mandiri; 3 nilai karakter bergotong royong; 10 nilai karakter bernalar kritis; dan 5 nilai karakter kreatif. Buku teks Bahasa Indonesia Kelas VIII SMP Kurikulum Merdeka sudah memuat nilai-nilai pendidikan karakter yang akan ditanamkan kepada siswa
Teknik Penciptaan dan Fungsi Humor Bahasa Jawa Ngapak pada Akun Tiktok @nanalbaliklagi, @rofiqkompak1, dan @raflychaniag0
Authors: Aisa Ahdanisa  , Nur Fateah
Published: September 2024

Humor merupakan suatu sarana penghibur diri yang digunakan seseorang ketika merasa penat setelah melakukan kegiatan sehari-hari. Humor bahasa Jawa ngapak saat ini banyak digunakan pada media sosial tiktok. Selain aksesnya yang mudah, pembawaan bahasa ngapak dan nada bicara konten kreator yang unik membuat humor bahasa Jawa ngapak pada media sosial tiktok banyak diminati masyarakat. Penelitian ini bertujuan untuk mendeskripsikan teknik penciptaan humor bahasa Jawa ngapak kategori language dan fungsi humor bahasa Jawa ngapak pada akun tiktok @nanalbaliklagi, @rofiqkompak1, dan akun tiktok @raflychaniag0. Penelitian ini termasuk penelitian deskriptif kualitatif dengan teknik pengumpulan data menggunakan teknik simak bebas libat cakap dan teknik catat. Data dalam penelitian ini berupa tuturan lisan dari beberapa konten tiktok dari akun tersebut. Teknik analisis data dilakukan dengan reduksi data untuk menentukan data yang relevan, kemudian melakukan penyajian data untuk menggambarkan hasil dari penelitian. Hasil penelitian ini menunjukkan teknik penciptaan humor dari akun tiktok yang dikaji terdiri atas: allusion, bombast, definition, exaggeration, infantilism, insults, irony, misunderstanding, repartee, dan sarcasm. Fungsi humor yang terdapat pada konten tiktok yang dikaji terdiri atas: fungsi memahami, fungsi mempengaruhi, dan fungsi menghibur.
Pengembangan Bahan Ajar Menulis Berorientasi Peningkatan Kemampuan Berpikir Kritis Berbasis Kecerdasan Majemuk
Authors: Olivia Juni Rosita Hutagalung  , Ramly Ramly , Hajrah Hajrah
Published: September 2024

Hasil Penelitian ini bertujuan mengukur tingkat validitas, efektivitas, dan kepraktisan bahan ajar menulis berorientasi pada peningkatan kemampuan berpikir kritis berbasis kecerdasan majemuk. Jenis penelitian yang digunakan adalah Penelitian dan Pengembangan (Research and Development) yang menghasilkan bahan ajar dengan model pengembangan ADDIE. Subjek Penelitian adalah semua peserta didik kelas X di UPTD SMAN 2 Toppoyo dan UPTD SMAN 1 Budong-Budong. Bahan ajar yang dikembangkan adalah bahan ajar menulis dengan materi esensial Teks Informatif yang berfokus pada peningkatan kemampuan berpikir kritis peserta didik dan memiliki ciri khas berbasis Kecerdasan Majemuk. Teknik pengumpulan data dengan analisis dokumen, survei dengan angket, wawancara, dan pengujian. Hasil penelitian sebagai berikut. 1) Hasil uji validitas dengan Uji Konsistensi Cohen’s Kappa bernilai 1 dengan interpretasi Perfect Agreement. 2) Hasil uji Efektivitas dengan Uji Non Parametrik Wilcoxon bernilai Asymp Sig (2-tailed) <0,001. Nilai <0,001 < 0,05 maka disimpulkan hipotesis diterima. 3) Hasil uji kepraktisan dengan Skala Guttman bernilai Kr=1 dan Ks=1. Nilai Kr=1≥0,9 maka skala dianggap layak dan Ks=1≥0,6 maka skala dianggap bagus. Hasil penelitian bahwa bahan ajar menulis berorientasi pada peningkatan kemampuan berpikir kritis berbasis kecerdasan majemuk dinyatakan valid, efektif, dan praktis.
Construction of a mobile application for wound assessment for nursing students and professionals
Authors: Lima Erica Valnis Moreira , Moraes Francisca Rhayra Gonçalves , Branco Nayra Ferreira Lima Castelo , Santos Lidyane Rodrigues Oliveira , Cordeiro Raimundo Flavio Dias , Araujo Fabiano Viana de , Vasconcelos Claudia Daniella Avelino
Published: September 2024

Objective: To develop a mobile application for wound analysis that includes the TIMERS framework, a human body map, and wound assessment criteria for nursing professionals and students. Method: This study employed a methodological research approach focused on technological development. The research was conducted in three stages: the pre-project phase, the structuring of the research through a literature review on the topic, and the evaluation phase, which involved developing the prototype. Results: A prototype of the application, Avalia Feridas, was initially created, limited to the Android operating system. This app includes the TIMERS framework, wound assessment criteria, and a human body map. The application aims to enhance nursing care by providing individualized interventions, thereby contributing to the wound healing process. Conclusion: The application supports the development of critical thinking in wound assessment, offering guidance to nursing students and professionals in their practice. The next objective is to validate the app, with the goal of making this tool available to the public.
The Relationship between Writing Skills, Writing Self-Efficiacy, and Writing Motivation of Gifted Students Enrolled in Science and Art Centers (SACs)
Authors: Yurtbakan Ergün , Bektaş Abdülkadir
Published: September 2024

The aim of this study is to examine the relationship between the writing skills of gifted secondary school students and their writing self-efficacy and motivation. This quantitative research was designed according to the correlational survey method. The research group consists of 81 7th-8th grade students attending at SACs in Trabzon. Data for the study were collected using the "Writing Self-Efficacy Scale," "Writing Motivation Scale," "Narrative Writing Assessment Form," and "Informative Text Writing Assessment Form." SPSS 21.0 software package was used for data analysis. At the end of the study carried out to determine the relationship between writing self-efficacy, motivation, and skills of gifted students, it was found that class, parental education, and family income variables did not create statistically significant differences in the writing self-efficacy, motivation, and skills (narrative and informative texts) of gifted students. However, the gender variable showed a statistically significant difference in favor of girls only in informative text writing skills. Furthermore, a relationship was identified between the writing self-efficacy and motivation of gifted students, but no relationship was found between their writing self-efficacy and skills. Additionally, although there was a relationship between the narrative text writing skills and informative text writing skills of gifted students, no relationship was observed between their writing skills and writing self-efficacy or motivation.