bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Gamma Irradiation on the Properties of Magnesium-Doped Hydroxyapatite in Chitosan Matrix
Authors: Predoi Daniela , Ciobanu Carmen Steluta , Iconaru Simona Liliana , Predoi Silviu Adrian , Chifiriuc Mariana Carmen , Raaen Steinar , Badea Monica Luminita , Rokosz Krzysztof
Published: August 2022

This is the first report regarding the effect of gamma irradiation on chitosan-coated magnesium-doped hydroxyapatite (xMg = 0.1; 10 MgHApCh) layers prepared by the spin-coating process. The stability of the resulting 10 MgHApCh gel suspension used to obtain the layers has been shown by ultrasound measurements. The presence of magnesium and the effect of the irradiation process on the studied samples were shown by X-ray photoelectron spectroscopy (XPS). The XPS results obtained for irradiated 10 MgHApCh layers suggested that the magnesium and calcium contained in the surface layer are from tricalcium phosphate (TCP; Ca3(PO4)2) and hydroxyapatite (HAp). The XPS analysis has also highlighted that the amount of TCP in the surface layer increased with the irradiation dose. The energy-dispersive X-ray spectroscopy (EDX) evaluation showed that the calcium decreases with the increase in the irradiation dose. In addition, a decrease in crystallinity and crystallite size was highlighted after irradiation. By atomic force microscopy (AFM) we have obtained images suggesting a good homogeneity of the surface of the non-irradiated and irradiated layers. The AFM results were also sustained by the scanning electron microscopy (SEM) images obtained for the studied samples. The effect of gamma-ray doses on the Fourier transform infrared spectroscopy (ATR-FTIR) spectra of 10 MgHApCh composite layers was also evaluated. The in vitro antifungal assays proved that 10 MgHApCh composite layers presented a strong antifungal effect, correlated with the irradiation dose and incubation time. The study of the stability of the 10 MgHApCh gel allowed us to achieve uniform and homogeneous layers that could be used in different biomedical applications.
Impact of Washing Parameters on Thermal Characteristics and Appearance of Proban®—Flame Retardant Material
Authors: Kaurin Tea , Pušić Tanja , Dekanić Tihana , Flinčec Grgac Sandra
Published: August 2022

Proban® is a multiphase treatment of cotton fabrics based on the formation of pre-condensates using the flame retardant (FR) agent tetrakis (hydroxymethyl) phosphonium salts (THPx). The assessment of the durability of a product demands a preliminary understanding of how relevant it is to extend its lifetime. It is therefore important to minimize the risk of agents impacting: (1) the protection level, (2) shape and dimensions, and (3) additional comfort characteristics of the fabric. This research focused on the impact of washing conditions on the durability of FR properties and appearance of Proban® cotton fabrics, which was systematically arranged through the variation in the chemistry distribution in the Sinner’s circle. The chemical share was varied in laboratory conditions as a simulation of industrial washing based on component dosing, where the temperature, time and mechanical agitation were constant. The washing of cotton fabrics was performed through 10 cycles in four baths containing high alkali components, medium alkali components, high alkali reference detergent and water. The environmental acceptability of washing procedures through effluent analysis was assessed by physico–chemical and organic indicators. The limited oxygen index (LOI), calorimetric parameters (micro combustion calorimetry), thermal stability and evolved gases during thermal decomposition (thermogravimetric analyzer (TGA) coupled with an infrared spectrometer (TG–IR)), surface examination (FE-SEM), spectral characteristics and pH of the aqueous extract of the fabrics before and after 10 washing cycles were selected for proof of durability. The medium alkali bath was confirmed as a washing concept for Proban® cotton fabric through the preservation of FR properties examined through LOI, TGA, TG–IR and MCC parameters and appearance color and low level of fibrillation.
Metallic and Metal Oxides Nanoparticles for Sensing Food Pathogens—An Overview of Recent Findings and Future Prospects
Authors: Ungureanu Camelia , Tihan Gratiela Teodora , Zgârian Roxana Gabriela , Fierascu Irina , Baroi Anda Maria , Răileanu Silviu , Fierăscu Radu Claudiu
Published: August 2022

Nowadays, special importance is given to quality control and food safety. Food quality currently creates significant problems for the industry and implicitly for consumers and society. The effects materialize in economic losses, alterations of the quality and organoleptic properties of the commercial products, and, last but not least, they constitute risk factors for the consumer’s health. In this context, the development of analytical systems for the rapid determination of the sanitary quality of food products by detecting possible pathogenic microorganisms (such as Escherichia coli or Salmonella due to the important digestive disorders that they can cause in many consumers) is of major importance. Using efficient and environmentally friendly detection systems for identification of various pathogens that modify food matrices and turn them into food waste faster will also improve agri-food quality throughout the food chain. This paper reviews the use of metal nanoparticles used to obtain bio nanosensors for the purpose mentioned above. Metallic nanoparticles (Au, Ag, etc.) and their oxides can be synthesized by several methods, such as chemical, physical, physico-chemical, and biological, each bringing advantages and disadvantages in their use for developing nanosensors. In the “green chemistry” approach, a particular importance is given to the metal nanoparticles obtained by phytosynthesis. This method can lead to the development of good quality nanoparticles, at the same time being able to use secondary metabolites from vegetal wastes, as such providing a circular economy character. Considering these aspects, the use of phytosynthesized nanoparticles in other biosensing applications is also presented as a glimpse of their potential, which should be further explored.
A Distance-Field-Based Pipe-Routing Method
Authors: Ueng Shyh-Kuang , Huang Hsuan-Kai
Published: August 2022

Pipes are commonly used to transport fuels, air, water, gas, hydraulic power, and other fluid-like materials in engine rooms, houses, factories, airplanes, and ships. Thus, pipe routing is essential in many industrial applications, including ship construction, machinery manufacturing, house building, laying out engine rooms, etc. To be functional, a pipe system should be economical while satisfying spatial constraints and safety regulations. Numerous routing algorithms have been published to optimize the pipe length and the number of elbows. However, relatively few methods have been designed to lay out pipes which strictly meet the spatial constraints and safety regulations. This article proposes a distance-field-based piping algorithm to remedy this problem. The proposed method converts the workspace into a 3D image and computes a distance field upon the workspace first. It then creates a feasible space out of the workspace by peeling the distance field and segmenting the 3D image. The resultant feasible space is collision-free and satisfies the spatial constraints and safety regulations. In the following step, a path-finding process, subjected to a cost function, is triggered to arrange the pipe inside the feasible space. Consequently, the cost of the pipe is optimized, and the pipe path rigidly meets the spatial constraints and safety regulations. The proposed method works effectively even if the workspace is narrow and complicated. In three experiments, the proposed method is employed to lay out pipes inside an underwater vehicle, a machinery room, and a two-story house, respectively. Not only do the resultant pipes possess minimal costs, but they also meet the spatial constraints and safety regulations, as predicted. In addition to developing the routing procedure, we also design a visualization subsystem to reveal the progression of the piping process and the variation of the workspace in the run time. Based on the displayed images, users can therefore evaluate the quality of the pipes on the fly and tune the piping parameters if necessary.
Effect of Biochar Modification by Vitamin C, Hydrogen Peroxide or Silver Nanoparticles on Its Physicochemistry and Tetracycline Removal
Authors: Tomczyk Agnieszka , Szewczuk-Karpisz Katarzyna
Published: August 2022

Chemical modification of biochars can improve their adsorption capacity relative to antibiotics, posing a serious threat to the environment. Therefore, this research is aimed at the treatment of sunflower husk biochar (BC) by vitamin C, hydrogen peroxide or silver nanoparticles and the impact of this procedure on the biochar porosity, surface chemistry, and ability to remove tetracycline (TC). During the study, BC was produced by pyrolysis of sunflower husks at 650 °C. All solids were characterized using potentiometric titration, nitrogen adsorption/desorption, Fourier transform infrared spectroscopy, etc. The experimental adsorption data was described by kinetics equations: pseudo-first order, pseudo-second order, and particle internal diffusion (IPD) models as well as by isotherms of Langmuir, Langmuir-Freundlich, and Redlich-Peterson. The obtained results indicated that the biochar upgraded by vitamin C (BCV) had the highest ability to attract antibiotic molecules and, as a result, the TC adsorption on its surface was the largest. Furthermore, the TC desorption from this material was minimal. The measured TC adsorbed amounts for the modified BCs were as follows: 47.75% (7.47 mg/g) for BCV, 37.35% (8.41 mg/g)-for biochar treated by hydrogen peroxide (BCH), and 42.04% (9.55 mg/g) for biochar modified by silver nanoparticles (BCA). The lowest adsorption level was noted for non-modified biochar, i.e., 34.17% (6.83 mg/g). Based on the presented results it can be stated that the upgraded biochars had a good potential to improve the tetracycline removal from aqueous media, e.g., groundwater.
Enhanced Thermal Performance of Composite Phase Change Materials Based on Hybrid Graphene Aerogels for Thermal Energy Storage
Authors: Shang Yu , Zhang Dong , An Minrong , Li Zhao
Published: August 2022

Thermal conductivity and latent heat are crucial performance parameters for phase change materials (PCMs) in thermal energy storage. To enhance the thermal performance of PCMs, with the help of graphene oxide (GO) acting as a dispersing agent, well-defined hybrid graphene aerogels (HGAs) with a three-dimensional (3D) porous structure were successfully synthesized by hydrothermal reaction of GO and graphene nanoplatelets (GNPs). GNPs, dispersing uniformly along the interconnecting graphene network, acted as thermal conductive fillers and supporting materials. Palmitic acid (PA) was impregnated into the HGA by vacuum forces. It was found that the thermal conductivity of the PA/HGA was enhanced without compromising heat storage capacity. Compared with PA, the PA/HGA with 4.2 wt% GNPs exhibited enhanced thermal conductivity of 2.1 W/mK and high latent heat of 206.2 J/g simultaneously. The PA/HGA with good thermal performance has potential applications in thermal energy storage.
Friction Performance Improvement of Phenolic/Rockwool Fibre Composites: Influence of Fibre Morphology and Distribution
Authors: Makni Fatma , Cristol Anne-Lise , Desplanques Yannick , Elleuch Riadh
Published: August 2022

The size and morphology of reinforcing fibres have a great influence on organic brake friction composite material properties and performance. This research aims to establish the link between friction material microstructure heterogeneity induced by rockwool fibre morphology and distribution and the resulting tribological behaviour. The adopted approach is based on simplified formulations designed to limit synergistic effects by reducing the number and size distribution of constituents. Two simplified materials are developed with different rockwool fibre size and morphology. The first material is elaborated with calibrated fibre balls, and the second one is performed with separated fibres. Friction and wear behaviour are correlated with thermal phenomena in order to reveal wear mechanisms and thus understand the link between microstructural characteristics and the resulting tribological behaviour. It was found that a regular size and distribution of rockwool fibre balls induce better tribological behaviour and enhance wear resistance. Indeed, a homogeneously distributed porosity, which is induced by fibre balls, favours the development and preservation of the load-bearing plateaus in the contact. This, consequently guarantees a stable friction and a reduced wear rate. Consequently, reducing microstructural heterogeneity, resulting from rockwool fibre morphology and distribution, improves the performance of composite friction material.
Preparation and Performance Study of Large Volume Foamed Lightweight Soil for an Intelligent Networked Vehicle Test Site
Authors: Liu Hao , Liu Gang , Wang Huqiang , Wan Huiwen , Xu Xiaoyang , Shen Cong , Xuan Jiaqi , He Qiqing
Published: August 2022

The foamed lightweight soil (FLS) with superior performance was prepared to be used as a subgrade filling material in an intelligent networked vehicle test site. The production process of practical engineering FLS is simulated in the laboratory. The performance of the prepared FLS is the same as that of practical engineering. The test results show that the FLS prepared with 30% cement, 30% granulated blast furnace slag, and 40% fly ash as cementing material has a flow factor of 175 mm. It has good fluidity and is easy to pump. Wet density reaches 593 kg/m3 within the range of the control index of 600 ± 30 kg/m3. The compressive strength of 7 d and 28 d reaches 0.82 MPa and 1.90 MPa, respectively, which is higher than the design strength of 0.5 MPa and 1.0 MPa. Compared with FLS made of pure cement as a cementing material, the FLS has a low heat of hydration, good volume stability, no cracks on the surface, excellent sulfate resistance, good economy, and low carbon characteristics. In the meantime, it can reduce 70% CO2 emissions in cement production. The advanced vehicle-mounted mobile intelligent control system is flexible and convenient in actual engineering construction. It can display the wet density of FLS online, which is easy to adjust and control to ensure the quality stability of FLS.
Insights into Polymeric Materials for Prosthodontics and Dental Implantology
Authors: Heboyan Artak , Zafar Muhammad Sohail , Karobari Mohmed Isaqali , Tribst João Paulo Mendes
Published: August 2022

Nowadays, a large variety of prostheses both in medicine and dentistry are increasingly made of polymers and polymer-based materials [...]
Influence of the Additive of Ceramic and Intermetallic Powders on the Friction Properties and Temperature of the Wet Clutch Disc
Authors: Yevtushenko Aleksander , Kuciej Michal , Grzes Piotr , Ilyushchanka Aleksander , Liashok Andrey
Published: August 2022

The basic function of friction clutches is to transfer the torque in the conditions of its smooth engagement without vibrations. Hard working conditions under high thermal and mechanical loads, leading to high temperature in the contact area, intense wear, and instability of the coefficient of friction impose restrictive criteria in the design of friction materials. In this paper, the results of experimental research of the effect of ceramic and intermetallic additives to the copper-based material of the friction disc of the clutch on the thermophysical and frictional properties were presented. Next, these properties were incorporated in the proposed contact 3D numerical model of the clutch to carry out computer simulations of the heating process and subsequent cooling. Based on the obtained experimental data and transient temperature changes of the friction and steel discs, the relations between the powder additives, thermophysical properties of the five friction materials, and coefficients of friction, wear, and temperature reached were discussed. Among these, it was found that when working with the lubrication, the largest values of the coefficient of friction 0.068 and wear 13.5  μm  km−1 were reached when using the 3 wt.% SiC additive.
Nanotube Functionalization: Investigation, Methods and Demonstrated Applications
Authors: Kharlamova Marianna V. , Paukov Maksim , Burdanova Maria G.
Published: August 2022

This review presents an update on nanotube functionalization, including an investigation of their methods and applications. The review starts with the discussion of microscopy and spectroscopy investigations of functionalized carbon nanotubes (CNTs). The results of transmission electron microscopy and scanning tunnelling microscopy, X-ray photoelectron spectroscopy, infrared spectroscopy, Raman spectroscopy and resistivity measurements are summarized. The update on the methods of the functionalization of CNTs, such as covalent and non-covalent modification or the substitution of carbon atoms, is presented. The demonstrated applications of functionalized CNTs in nanoelectronics, composites, electrochemical energy storage, electrode materials, sensors and biomedicine are discussed.
Photogrammetry-Based Volume Measurement Framework for the Particle Density Estimation of LECA
Authors: Brzeziński Karol , Duda Adam , Styk Adam , Kowaluk Tomasz
Published: August 2022

This paper presents a photogrammetry-based volume measurement framework for the particle density estimation of Lightweight expanded clay aggregate (LECA). The results are compared with computed tomography (CT) and Archimedes’ method measurements. All of the steps required in order to apply the proposed approach are explained. Next, we discuss how the interpretation of open pores affects the results of volume measurements. We propose to process the shapes obtained from different methods by applying an Ambient Occlusion algorithm with the same threshold, t = 0.175. The difference between the CT and SfM methods is less than 0.006 g/cm3, proving that the photogrammetry-based approach is accurate enough. The Archimedes’ method significantly overestimates the density of the particles. Nevertheless, its accuracy is acceptable for most engineering purposes. Additionally, we evaluate the accuracy of shape reconstruction (in terms of the Hausdorff distance). For 95% of the grain’s surface, the maximum error is between 0.073 mm and 0.129 mm (depending on the grain shape). The presented approach is helpful for measuring the particle density of porous aggregates. The proposed methodology can be utilized in order to estimate intergranular porosity, which is valuable information for the calibration of DEM models.
The Stability Consequences Promoted by Doping Metallic Atoms on the Degradation of Poly (ε-Caprolactone)
Authors: Zaharescu Traian , Borbath Tunde , Mariș Marius , Borbath Istvan , Mariș Mihaela
Published: August 2022

The stability of polymer materials is essentially determined by the molecular structure and the presence of additives and impurities. When a polymer substrate is subjected to vigorous damage by an energetic treatment, the molecular scission generates fragments, which may be oxidized by the diffused oxygen. The traces of oxide catalysts that may be accidentally incorporated into the polymer materials initiate a faster oxidation that influences the material durability. This study presents the behavior of poly (ε-caprolactone) (PCL) loaded with 2 wt% PbZrO3 previously doped with foreign atoms (Cr, Nd, Mg, Mn, Ti) at the concentration of 0.1 mol%. The investigation procedure, chemiluminescence, reveals the acceleration of the degradation of PCL. The contribution of the metallic traces existing in the structure of PbTiO3 powder is characterized by the activation energies (Ea) involved in the propagation of oxidation. The free radicals are involved in a faster oxidation, when the polymer substrate is heated at superior rates. The comparison of the oxidation levels at the extended period of heating and irradiation indicates the sustained activities of metallic traces acting in oxide powder fillers, especially at temperatures exceeding 150 °C. The essential considerations on material strength against oxidation are presented.
Q Factor Enhancement of Open 2D Resonators by Optimal Placement of a Thin Metallic Rod in Front of the Longitudinal Slot
Authors: Vinogradova Elena D. , Smith Paul D.
Published: August 2022

A rigorous approach was employed for the accurate evaluation of the electromagnetic interaction between a thin metallic rod and a two-dimensional (2D) slotted cavity. The problem was posed as a classical boundary value problem for the Helmholtz equation in which a 2D slotted open cavity is bounded by an arbitrary but otherwise smooth contour with a longitudinal slit. Using the method of analytical regularization, the problem was transformed to well-conditioned coupled infinite systems of linear algebraic equations for the Fourier coefficients in the expansions of induced surface currents on the rod and slotted cavity. When truncated to finite size, their solutions exhibit fast convergence to the exact solution as the order is increased. This feature makes it possible to investigate the spectral and scattering characteristics of the coupled cavity and rod to within any desired accuracy. In this paper, the complex eigenvalues for a slotted cavity in the presence of a thin rod and the dependence upon their relative location were investigated, particularly to find where there is significant or optimal enhancement of the Q factor. Such optimisation may be exploited in the design of advanced slot antennas and slotted waveguides.
Structural and Functional Characterization of Orcokinin B-like Neuropeptides in the Cuttlefish (Sepia officinalis)
Authors: Endress Maxime , Zatylny-Gaudin Céline , Leprince Jérôme , Lefranc Benjamin , Corre Erwan , Le Corguillé Gildas , Bernay Benoît , Leduc Alexandre , Rangama Jimmy , Mouret Liza , Lafont Anne-Gaëlle , Bondon Arnaud , Henry Joël
Published: August 2022

The cuttlefish (Sepia officinalis) is a Cephalopod mollusk that lives in the English Channel and breeds in coastal spawning grounds in spring. A previous work showed that the control of egg-laying is monitored by different types of regulators, among which neuropeptides play a major role. They are involved in the integration of environmental cues, and participate in the transport of oocytes in the genital tract and in the secretion of capsular products. This study addresses a family of neuropeptides recently identified and suspected to be involved in the control of the reproduction processes. Detected by mass spectrometry and immunocytochemistry in the nerve endings of the accessory sex glands of the females and ovary, these neuropeptides are also identified in the hemolymph of egg-laying females demonstrating that they also have a hormone-like role. Released in the hemolymph by the sub-esophageal mass, a region that innervates the genital tract and the neurohemal area of the vena cava, in in vitro conditions these neuropeptides modulated oocyte transport and capsular secretion. Finally, in silico analyses indicated that these neuropeptides, initially called FLGamide, had extensive structural homology with orcokinin B, which motivated their name change.
Evaluation of Bicanalicular Nasolacrimal Duct Intubation as an Adjunct in Surgical Ectropion Correction
Authors: Papazoglou Anthia , Chrysochoou Triantafyllia , Goldblum David , Tschopp Markus , Enz Tim J.
Published: August 2022

Background and Objectives: We aimed to analyze and compare the outcomes of conventional ectropion surgery procedures with and without concurrent bicanalicular nasolacrimal duct intubation to identify if the combination of procedures could serve as a novel surgical approach to treat lower eyelid ectropion. Materials and Methods: A retrospective review of all patients who underwent surgical correction for lower eyelid ectropion at the Cantonal Hospital of Aarau between January 2019 and December 2020 was performed. Patient medical records were examined for etiology, surgical correction technique and intra- and postoperative complications. The postoperative punctal position, the pre- and postoperative epiphora and reoperation rate were also documented. Two study groups consisting of cases with isolated and combined procedures were compared, with respect to postoperative punctual and lower lid position. Results: A total of 53 lower eyelids (35 patients) were included in this study. Six months postoperatively, the correct punctum position (p = 0.1188) and improvement of epiphora (p = 0.7739) did not significantly differ between the two groups. More complications were seen in the nasolacrimal duct intubation group (p = 0.0041), which consisted of cheese wiring and one tube dislocation. Conclusion: In our study, bicanalicular nasolacrimal intubation during ectropion surgery does not seem to improve the outcome of ectropion surgery and is, therefore, not recommended on a routine basis.
Management of Class III Malocclusion and Maxillary Transverse Deficiency with Microimplant-Assisted Rapid Palatal Expansion (MARPE): A Case Report
Authors: Shih Sin-Ni , Ho Kwok-Hing , Wang Chih-Wei , Wang Kai-Long , Hsieh Shun-Chu , Chang Heng-Ming
Published: August 2022

Microimplant-assisted rapid palatal expansion (MARPE) has been demonstrated successfully in maxillary expansion in late adolescence and adulthood. The maxillary advancement accompanied by expansion is frequently anticipated, which is beneficial for the treatment of class III malocclusion. Airway volume increase can also be noted in some cases from the measurement of cone beam computerized tomography (CBCT) after expansion. The objective of this case report is to demonstrate the feasibility of applying MARPE on late adolescence patients with maxillary transverse deficiency and to present the changes in transverse and anteroposterior dimensions as well as the volume increase in velopharyngeal airway after MARPE. A 15-year-old female presented class III skeletal pattern. She had maxillary transverse deficiency with moderate crowding and posterior/anterior crossbites. Maxillary Skeletal Expander (MSE; Biomaterials Korea Inc.) type-2 was used as a MARPE device in this case. After four weeks of maxillary expansion, a significant amount of expansion was achieved and the anterior crossbite was spontaneously corrected. Fixed appliance treatment was commenced four weeks after MARPE with 0.022-slot preadjusted brackets (MBT prescription). Temporary anchorage devices (TADs) were placed over the mandibular buccal shelves for posterior teeth distalization and crowding relief. After 25 months of treatment, the facial profile was improved with maxillary advancement (SNA: 83° to 83.5°) and mandibular backward rotation (SNB: 83° to 82°; SN-MP: 34.5° to 35°). In this case, MARPE not only engenders significant transverse correction but also aids in anteroposterior change. The treatment effects of maxillary advancement and mandibular backward rotation can lead to a more esthetic profile in skeletal class III cases.
Risk Factors of Early Atrial Fibrillation Recurrence Following Electrical Cardioversion When Left Ventricular Ejection Fraction Is Preserved
Authors: Karaliūtė Rasa , Leleika Arnoldas , Apanavičiūtė Ieva , Kazakevičius Tomas , Mizarienė Vaida , Zabiela Vytautas , Kavoliūnienė Aušra , Ragaišytė Nijolė , Urbonienė Daiva , Šakalytė Gintarė
Published: August 2022

Background and objectives: To identify clinical, echocardiographic, and laboratory parameters that affect the early recurrence of atrial fibrillation (AF) after restoring sinus rhythm (SR) by electrical cardioversion (ECV), and to determine whether left atrial (LA) strain, as a noninvasive indicator reflecting fibrosis, is associated with laboratory indicators affecting the development of fibrosis, interleukin 6 (IL-6) or tumor necrosis factor α (TNF-α). Materials and Methods: The study included 92 persistent AF patients who underwent elective ECV. The effective maintenance of SR was evaluated after 40 ± 10 days of ECV. Echocardiography, inflammatory markers (high-sensitivity c-reactive protein (hs-CRP), IL-6, and TNF-α), and natriuretic peptides (N-terminal pro b-type natriuretic peptide (NT-proBNP) and N-terminal pro a-type natriuretic peptide (NT-proANP)) were assessed. Results: After a 40 ± 10 days observation period, 51 patients (55.4%) were in SR. Patients with AF recurrence had a significantly longer duration of AF (p = 0.008) and of arterial hypertension (p = 0.035), lower LA ejection fraction (p = 0.009), lower LA strain (p < 0.0001), higher left ventricular global longitudinal strain (p = 0.001), and a higher E/e‘ ratio (p < 0.0001). LA strain was an independent predictor of early AF recurrence (OR: 0.65; 95% Cl 0.5–0.9, p = 0.004). LA strain < 11.85% predicted AF recurrence with 70% sensitivity and 88% specificity (AUC 0.855, 95% CI 0.77–0.94, p < 0.0001). LA strain demonstrated the association with NT-proBNP (r = −0.489, p < 0.0001) and NT-proANP (r = −0.378, p = 0.002), as well as with hs-CRP (r = −0.243, p = 0.04). Conclusions: LA strain appeared to be the most accurate predictor of early AF recurrence after ECV in patients with persistent AF. LA strain inversely correlated with NT-proBNP and NT-proANP, but no significant association with any of the inflammatory markers was identified.
Sessile Drop Method: Critical Analysis and Optimization for Measuring the Contact Angle of an Ion-Exchange Membrane Surface
Authors: Ponomar Maria , Krasnyuk Ekaterina , Butylskii Dmitrii , Nikonenko Victor , Wang Yaoming , Jiang Chenxiao , Xu Tongwen , Pismenskaya Natalia
Published: August 2022

The contact angle between a membrane surface and a waterdrop lying on its surface provides important information about the hydrophilicity/hydrophobicity of the membrane. This method is well-developed for solid non-swelling materials. However, ion-exchange membranes (IEMs) are gel-like solids that swell in liquids. When an IEM is exposed to air, its degree of swelling changes rapidly, making it difficult to measure the contact angle. In this paper, we examine the known experience of measuring contact angles and suggest a simple equipment that allows the membrane to remain swollen during measurements. An optimized protocol makes it possible to obtain reliable and reproducible results. Measuring parameters such as drop size, water dosing speed and others are optimized. Contact angle measurements are shown for a large number of commercial membranes. These data are supplemented with values from other surface characteristics from optical and profilometric measurements.
Effect of Heat Treatment on Ductility and Precipitation Size of Additively Manufactured AlSi10Mg
Authors: Megahed Sandra , Bühring Jannik , Duffe Tobias , Bach Aleksandar , Schröder Kai-Uwe , Schleifenbaum Johannes Henrich
Published: August 2022

Laser powder bed fusion (LPBF) is a promising technology to manufacture complex components. Aluminium (Al) alloys are extensively implemented in automotive and aerospace applications for their exceptional strength and stiffness to weight ratios. AlSi10Mg is a precipitation strengthened alloy. Due to the high cooling rate during the LPBF process, a fine microstructure in as-built samples is expected, increasing strength and hardness values. However, the ductility of as-built AlSi10Mg alloys is limited. Heat treatment allows control of microstructure influencing the mechanical properties and ductility. In this study, AlSi10Mg samples with a relative density >99.5% were manufactured with LPBF. Surface roughness values of 10.86 µm were achieved. Tensile and three-point bending samples were printed for analysis. Since load conditions of lattice structures in compression are much more complex compared to that of volume samples, increasing tensile ductility is not sufficient to determine the suitability of lattice structures for applications where high deformations are required. Therefore, lattice structures for compression testing were manufactured and individually heat treated to achieve a ductility of at least 20%. The precipitation size was found to increase depending on heat treatment from 0.44 µm up to 2.25 µm, giving insight on deformation behavior.
Thyroid Hormones Are Not Associated with Plasma Osteocalcin Levels in Adult Population with Normal Thyroid Function
Authors: Pleić Nikolina , Brdar Dubravka , Gunjača Ivana , Babić Leko Mirjana , Torlak Vesela , Punda Ante , Polašek Ozren , Hayward Caroline , Zemunik Tatijana
Published: August 2022

Thyroid hormones (THs) play an indispensable role in skeletal development and bone remodeling. Some studies have reported associations of THs with serum osteocalcin (OC) levels, but the results are quite inconsistent and the molecular mechanism of their simultaneous or interdependent activity on bone is almost unknown. Therefore, the aim of this study was to determine the possible associations of plasma THs with plasma OC levels and the possible mediating effect of OC on the relationship between THs and bone mineral density (BMD). For this purpose, out of the initial 1981 participants, we selected healthy euthyroid participants controlled for available confounding factors that can affect thyroid function and bone metabolism (N = 694). Given our results, we could not confirm any associations of THs with plasma OC levels nor the mediating effect of OC on the relationship between THs and BMD in euthyroid population. In the group of women controlled for menopause status (N = 396), we found a significant negative association of body mass index (BMI) with OC levels (β = −0.14, p = 0.03). We also found a negative association of free triiodothyronine (fT3) (β = −0.01, p = 0.02) and age (β = −0.003, p < 0.001) with BMD, and a positive association of BMI (β = 0.004, p < 0.001) and male gender (β = 0.1, p < 0.001) with BMD. In addition, we found significantly higher plasma OC levels and lower values of BMD in postmenopausal euthyroid women compared with premenopausal euthyroid women. In our opinion, the results of previous studies suggesting an association between circulating THs and serum OC levels may be influenced by an inconsistent selection of participants and the influence of confounding factors.
Analysis of a Vegetable Oil Performance in a Milling Process by MQL Lubrication
Authors: Afonso Inês S. , Pereira José , Ribeiro António E. , Amaral Joana S. , Rodrigues Nuno , Gomes José R. , Lima Rui , Ribeiro João
Published: August 2022

In this work, we carried out a comparison between the dry machining of an aluminum block with conventional cutting oil and a block with vegetable oil. The two oils had different flow rates. Using the Taguchi method, it was possible to determine the matrices for optimizing the best parameters for each group of tests. Then, we studied the utility of using vegetable oil as a cutting lubricant. We found that the vegetable oil studied in this work had good properties in terms of reducing cutting temperatures but was less effective than conventional cutting oil in reducing the surface roughness of the machined part. Tribological tests were carried out to understand the influence of the selected lubricants in reducing friction and wear. After the sliding experiments, which were performed without lubrication in the presence of the same lubricants that were used in the machining tests and in the presence of distilled water, we concluded that vegetable oil has satisfactory lubricating properties that are similar to those of the conventional cutting fluid, indicating a potential for consideration as an effective alternative to the conventional cutting fluid, with economic, environmental, and health advantages.
Development of Electrostatic Microactuators: 5-Year Progress in Modeling, Design, and Applications
Authors: Morkvenaite-Vilkonciene Inga , Bucinskas Vytautas , Subaciute-Zemaitiene Jurga , Sutinys Ernestas , Virzonis Darius , Dzedzickis Andrius
Published: August 2022

The implementation of electrostatic microactuators is one of the most popular technical solutions in the field of micropositioning due to their versatility and variety of possible operation modes and methods. Nevertheless, such uncertainty in existing possibilities creates the problem of choosing suitable methods. This paper provides an effort to classify electrostatic actuators and create a system in the variety of existing devices. Here is overviewed and classified a wide spectrum of electrostatic actuators developed in the last 5 years, including modeling of different designs, and their application in various devices. The paper provides examples of possible implementations, conclusions, and an extensive list of references.
Oral Microbiota Profile in Patients with Anti-Neutrophil Cytoplasmic Antibody–Associated Vasculitis
Authors: Esberg Anders , Johansson Linda , Berglin Ewa , Mohammad Aladdin J. , Jonsson Andreas P. , Dahlqvist Johanna , Stegmayr Bernd , Johansson Ingegerd , Rantapää-Dahlqvist Solbritt
Published: August 2022

Microbiota has been associated with autoimmune diseases, with nasal Staphylococcus aureus being implicated in the pathogenesis of anti-neutrophil cytoplasmic antibody–associated vasculitis (AAV). Little is known about the role of oral microbiota in AAV. In this study, levels of IgG antibodies to 53 oral bacterial species/subspecies were screened using immunoblotting in plasma/serum in pre-symptomatic AAV-individuals (n = 85), matched controls, and established AAV-patients (n = 78). Saliva microbiota from acute-AAV and controls was sequenced from 16s rDNA amplicons. Information on dental status was extracted from a national register. IgG levels against oral bacteria were lower in established AAV versus pre-AAV and controls. Specifically, pre-AAV samples had, compared to controls, a higher abundance of periodontitis-associated species paralleling more signs of periodontitis in established AAV-patients than controls. Saliva microbiota in acute-AAV showed higher within-sample diversity but fewer detectable amplicon-sequence variants and taxa in their core microbiota than controls. Acute-AAV was not associated with increased abundance of periodontal bacteria but species in, e.g., Arthrospira, Staphylococcus, Lactobacillus, and Scardovia. In conclusion, the IgG profiles against oral bacteria differed between pre-AAV, established AAV, and controls, and microbiota profiles between acute AAV and controls. The IgG shift from a pre-symptomatic stage to established disease cooccurred with treatment of immunosuppression and/or antibiotics.
Modes of Occurrence of Critical Metal Elements (Li, REEs and Other Critical Elements) in Low-Grade Bauxite from Southern Shanxi Province, China
Authors: Zhang Shangqing , Zhao Fenghua , Liu Dongna , Zhao Lei , Zhang Xiaohui , Lin Junwei , Dong Haiyu , Zhao Shuang , Liu Xuefei , Zan Minjie
Published: August 2022

The low-grade bauxite in southern Shanxi Province, China is enriched in multiple critical metal elements, including Li, Ga, V, Se, and rare earth elements (REEs), which have reached the standard of comprehensive utilization as independent deposits or associated resources. Even more importantly, identifying the modes of occurrence of these critical elements is essential for designing technologies to extract critical metals from bauxite ores. This study used a combination of direct (X-ray diffraction, scanning electron microscopy–energy dispersive X-ray spectroscopy, and micro-X-ray fluorescence spectrometer), and indirect (size sieving method, float-sink experiment, and correlation analysis) methods to effectively reveal the distribution of critical elements in the different identified mineral phases. The results regarding the low-grade bauxite are as follows: Li was mainly hosted in cookeite as an independent mineral; Ga was mainly associated with diaspore; anatase is the main carrier mineral for V; REEs were present in the low-grade bauxite in multiples modes of occurrence, the most common of which were goyazite, and to a lesser extent, florencite; Se primarily occurs in sulfides. This study contributes to the development and utilization of these essential metal resources in bauxite by providing a useful reference.
Editorial for Special Issue “Risk Assessment, Management and Control of Mining Contamination”
Authors: Lam Elizabeth J. , Bernardo-Sánchez Antonio , Sokoła-Szewioła Violetta
Published: August 2022

The exploitation of mineral resources around the world has always been a matter of controversy among governments, production companies, and organized society, giving rise particularly to conflicts about environmental matters [...]
Pomegranate Oil’s Potential as an Anti-Obesity Ingredient
Authors: Machado Manuela , Costa Eduardo M. , Silva Sara , Rodriguez-Alcalá Luís M. , Gomes Ana M. , Pintado Manuela
Published: August 2022

In recent years, pomegranate oil has obtained more attention due to its content of conjugated linolenic acids and possible application in the prevention of many diseases. The purpose of this work was to evaluate the potential ability of pomegranate oil to modulate obesity-related metabolism and immune response using in vitro models. In this regard, pomegranate oil was characterized in terms of fatty acids profile, tocopherols and phytosterols, and antioxidant capacity. After evaluation of the safety profile, pomegranate oil’s capacity to modulate obesity-related metabolism was evaluated through adipolysis and adipokines secretion quantification in 3T3-L1 differentiated adipocytes and hepatic lipid accumulation assay in Hep G2 hepatocytes. The immunomodulatory activity was evaluated in Caco-2 cells by quantification of pro-inflammatory cytokines IL-6, IL-8, and TNF-α. This oil showed high antioxidant capacity and was mainly composed of conjugated fatty acid, namely punicic acid. Its chemical composition was responsible for its capacity to reduce the lipid accumulation in Hep G2 cells and 3T3-L1 differentiated adipocytes. In short, pomegranate oil shows great potential for the development of functional foods and nutraceuticals targeting obesity.
Selective Integrin α5β1 Targeting through Spatially Constrained Multivalent DNA-Based Nanoparticles
Authors: Kurisinkal Eva E. , Caroprese Vincenzo , Koga Marianna M. , Morzy Diana , Bastings Maartje M. C.
Published: August 2022

Targeting cells specifically based on receptor expression levels remains an area of active research to date. Selective binding of receptors cannot be achieved by increasing the individual binding strength, as this does not account for differing distributions of receptor density across healthy and diseased cells. Engaging receptors above a threshold concentration would be desirable in devising selective diagnostics. Integrins are prime target candidates as they are readily available on the cell surface and have been reported to be overexpressed in diseases. Insights into their spatial organization would therefore be advantageous to design selective targeting agents. Here, we investigated the effect of activation method on integrin α5β1 clustering by immunofluorescence and modeled the global neighbor distances with input from an immuno-staining assay and image processing of microscopy images. This data was used to engineer spatially-controlled DNA-scaffolded bivalent ligands, which we used to compare trends in spatial-selective binding observed across HUVEC, CHO and HeLa in resting versus activated conditions in confocal microscopy images. For HUVEC and CHO, the data demonstrated an improved selectivity and localisation of binding for smaller spacings ~7 nm and ~24 nm, in good agreement with the model. A deviation from the mode predictions for HeLa was observed, indicative of a clustered, instead of homogeneous, integrin organization. Our findings demonstrate how low-technology imaging methods can guide the design of spatially controlled ligands to selectively differentiate between cell type and integrin activation state.
Heterogeneous Catalysis of Ozone Using Iron–Manganese Silicate for Degradation of Acrylic Acid
Authors: Liu Yue , Wang Congmin , Guo Rong , Li Juexiu , Zhao Quan , Wang Weiqiang , Qi Fei , Liu Haifang , Li Yang , Zheng Huifan
Published: August 2022

Iron–manganese silicate (IMS) was synthesized by chemical coprecipitation and used as a catalyst for ozonating acrylic acid (AA) in semicontinuous flow mode. The Fe-O-Mn bond, Fe-Si, and Mn-Si binary oxide were formed in IMS on the basis of the results of XRD, FTIR, and XPS analysis. The removal efficiency of AA was highest in the IMS catalytic ozonation processes (98.9% in 15 min) compared with ozonation alone (62.7%), iron silicate (IS) catalytic ozonation (95.6%), and manganese silicate catalytic ozonation (94.8%). Meanwhile, the removal efficiencies of total organic carbon (TOC) were also improved in the IMS catalytic ozonation processes. The IMS showed high stability and ozone utilization. Additionally, H2O2 was formed in the process of IMS catalytic ozonation. Electron paramagnetic resonance (EPR) analysis and radical scavenger experiments confirmed that hydroxyl radicals (•OH) were the dominant oxidants. Cl−, HCO3−, PO43−, Ca2+, and Mg2+ in aqueous solution could adversely affect AA degradation. In the IMS catalytic ozonation of AA, the surface hydroxyl groups and Lewis acid sites played an important role.
Effects of PEG Chain Length on Relaxometric Properties of Iron Oxide Nanoparticles-Based MRI Contrast Agent
Authors: Ge Jianxian , Li Cang , Wang Ning , Zhang Ruru , Afshari Mohammad Javad , Chen Can , Kou Dandan , Zhou Dandan , Wen Ling , Zeng Jianfeng , Gao Mingyuan
Published: August 2022

Iron oxide nanoparticles (IONPs) as magnetic resonance imaging (MRI) contrast agents have received considerable interest due to their superior magnetic properties. To increase the biocompatibility and blood circulation time, polyethylene glycol (PEG) is usually chosen to decorate IONPs. Although the surface effect induced by the PEGylation has an impact on the relaxometric properties of IONPs and can subsequently affect the imaging results, the occurrence of particle aggregation has troubled researchers to deeply explore this correlation. To shed light on this relationship, three diphosphonate PEGs with molecular weights of 1000, 2000, and 5000 Da were used to replace the hydrophobic oleate ligands of 3.6 nm and 10.9 nm IONPs. Then, the contrast enhancement properties of the resultant “aggregation-free” nanoparticles were carefully evaluated. Moreover, related theories were adopted to predict certain properties of IONPs and to compare with the experimental data, as well as obtain profound knowledge about the impacts of the PEG chain length on transverse relaxivity (r2) and longitudinal relaxivity (r1). It was found that r2 and the saturated magnetization of the IONPs, independent of particle size, was closely related to the chain length of PEG. The results unveiled the correlation between the chain length of the coated PEG and the relaxometric properties of IONPs, providing valuable information which might hold great promise in designing optimized, high-performance IONPs for MRI-related applications.
One-Pot Synthesis of HRP&SA/ZIF-8 Nanocomposite and Its Application in the Detection of Insecticidal Crystalline Protein Cry1Ab
Authors: Ye Ranfeng , Chen Hao , Li He
Published: August 2022

This study reported the functionality integration of zeolitic imidazolate framework-8 (ZIF-8) with horseradish peroxidase (HRP) and streptavidin (SA) for the synthesis of a HRP&SA/ZIF-8 nanocomposite through one-pot coprecipitation. The synthesized HRP&SA/ZIF-8 nanocomposite was then employed as the ideal signal tag for application in the enzyme-linked immunosorbent assay (ELISA) and exhibited excellent sensitivity, selectivity and accuracy in the detection of insecticidal crystalline (Cry) protein Cry1Ab as a transgenic biomarker with a detection limit of 4.8 pg/mL. This proposed method provides a new way for the detection of transgenic biomarkers in food and may inspire further integration of a variety of biomolecules into ZIF-8 for applications ranging from biosensing, biomedicine, and catalysis to energy.