bluuebunny/crossref_metadata_2025 huggingface dataset:
Hyperbaric Oxygen Therapy, a Possible New Approach in the Treatment of Retinal Damage in Methanol Poisoning in Rats
Authors: Baktir Mehmet Akif
Published: August 2023

It has been established that peroxidation, inflammatory processes, and organ damage are involved in the pathogenesis of methanol intoxication. Research has shown that using hyperbaric oxygen reduces oxidative stress, inflammation, and tissue damage. In this research, it was investigated how hyperbaric oxygen therapy affected methanol-induced peroxidation and retinal damage in rats. The animals were classified into six categories (n = 8): control group (C), nitrous oxide (N2O) treated group, hyperbaric oxygen (HBO) treated group, methanol (MeOH) treated group, N2O+methanol treated group (N2O+MeOH) and N2O+methanol+hyperbaric oxygen (N2O+MeOH+HBO) treated group. Folate deficiency was started with N2O, four hours before the starting dose (4g/kg) of methanol. The rats were given a methanol maintenance dose (2g/kg, i.p) 24h and 48h after the starting dose. After each methanol administration, rats were given HBO (2 ATA) for 1 hour. Methanol intoxication decreased plasma folic acid levels while increasing formate levels and oxidative stress index and it caused a decrease in the amount of the retinal ganglion cells and thinned the total retinal thickness in folate-deficient mice. HBO treatment reduced the oxidative stress index but did not adequately improve retinal healing. Our findings indicate that the HBO treatment used to treat retinal damage in methanol poisoning was ineffective. However, increasing the duration of HBO therapy may be effective in preventing methanol-induced retinal damage
Alterations of the Oestrous Cycle and Increase in the Blood Pressure in Normotensive Female Rats by Continuous Exposure to Light
Authors: Palacios Javier
Published: August 2023

The study aims to investigate changes on some cardiac parameters of normotensive female rats due to continual exposure to light. Three months old female Wistar rats were subjected to varying light cycles and intensities, following which cardiovascular parameters were recorded continuously at days 0, 10, 15, 20, 25 and 30. We calculated and recorded the mean arterial pressure, pulse pressure, peripheral resistance and cardiac output. It was observed that continuous exposure to light for 10 days significantly increased the mean arterial pressure (MAP; 103±1 mmHg control vs. 117±6 mmHg at 20 min; P<0.05) and the systolic blood pressure (SBP; 111±1 mmHg control vs. 130±5 mmHg at 20 min; P<0.05). Heart rate (HR) did not significantly change during the exposure to light. However, the pulse pressure (PP) increased at day 20 on exposure to light (18±1 mmHg control vs. 32±4 mmHg at 20 min; P<0.05). It also reduced the peripheral resistance, while increasing the cardiac output in the female rats. It also elevated oestrogen plasma levels and LF/HF ratio, which is a spectral component of ECG denoting heart rate variability (HRV). Continuous exposure to light may induce stress in female rats, leading to hormonal blood pressure, and sympathovagal imbalances
A TRANSPOSIÇÃO DAS METÁFORAS ONTOLÓGICAS CONCEPTUAIS; DO PLANO MENTAL PARA A LINGUAGEM NA POÉTICA DE CECÍLIA MEIRELES
Authors:   , SILVA NIKELLY MARIA ALVES DA
Published: August 2023

Este trabalho tem como objetivo apresentar a teoria da
metáfora conceptual proposta pelos filósofos George Lakoff e
Mark Johnson que está em seu livro Metaphor we live by –
teoria da metáfora conceptual e com base em suas referências
teóricas relatar um estudo analítico da metáfora ontológica na
poética de seis poemas da escritora Cecília Meireles: ‘'Alva'',
‘'Canção – pus meu sonho num navio'', Romance XXIV ou Da
bandeira da Inconfidência, ‘'Solombra'' “Ou isto ou aquilo” e
‘'Pergunta''. A essência que perpassa esses poemas é a
questão do cunho filosófico, da efemeridade das coisas, do
tempo, da vida, do amor, assuntos fundamentalmente ligados
à abstração dos fatos, sendo possível analisar, a linguagem,
símbolos por meios da metáfora supracitada. Nesse sentido a
metáfora é o instrumento linguístico importantíssimo que
possuímos para criar novos conhecimentos, para entender o
mundo em que vivemos e principalmente para
compreendermos a nossa cultura. O estudo da metáfora como
fenômeno cognitivo é investigação recente das ciências da
linguagem, inserido na perspectiva de que a linguagem não é
uma faculdade cognitiva autônoma, mas ligada a outras
habilidades do pensamento humano. A pesquisa foi guiada
por um contexto teórico bibliográfico da autora supracitada,
objetivando gerar conhecimentos novos para o avanço das
análises metafóricas linguísticas e literárias, obtendo
resultados confiáveis e com possibilidades de serem
generalizados para outros casos.

Palavras-chave: Metáfora Conceptual, Metáfora literária, Cecília
Meireles.
Proposição e resolução de problemas na educação superior: contribuições para a aprendizagem de análise combinatória
Authors:   , Gieseler Leonardo Cristiano
Published: August 2023

Esta pesquisa foi desenvolvida no Programa de Pós-Graduação em Ensino de Ciências Naturais e Matemática (PPGECIM), na linha de pesquisa Formação e Práticas docentes em contextos de Ensino de Ciências Naturais e Matemática, da Universidade Regional de Blumenau (FURB), no estado de Santa Catarina (SC), Brasil. Na Educação Matemática, o ensino através da Proposição de Problemas recentemente vem sendo investigado pela comunidade científica nacional e internacional, que tem relatado contribuições desta abordagem para a aprendizagem matemática dos estudantes. Nesse aspecto, esta pesquisa tem por objetivo analisar contribuições da proposição e resolução de problemas para a aprendizagem de Análise Combinatória. A investigação foi desenvolvida com estudantes dos cursos de graduação, bacharelado, em Ciência da Computação e Sistemas de Informação, e se caracteriza como uma pesquisa de natureza qualitativa e, em relação aos procedimentos adotados, como uma investigação-ação. Após se constituir o referencial teórico da pesquisa, desenvolveram-se atividades com base na abordagem de ensino que norteia este estudo. Nesse contexto, a fim de propiciar a construção dos dados, utilizou-se a observação sistemática como principal instrumento, bem como se fez o uso de registro documental das atividades produzidas pelos estudantes e de gravações audiovisuais das aulas. Para a análise dos dados, considerou-se duas categorias gerais, a aprendizagem matemática e o desenvolvimento de aspectos formativos pelos estudantes. Como resultados, destaca-se que o desenvolvimento da aprendizagem matemática se inicia antes mesmo dos problemas serem apresentados para serem resolvidos. Bem como, constata-se que, apenas ao ler um problema elaborado pelos estudantes, não é possível verificar se houve aprendizagem matemática sem analisar a forma com a qual ocorreu a etapa da formulação do problema. Em relação à proposição de problemas, constata-se que o tipo de ponto de partida da atividade pode guiar os tipos de problemas que os estudantes irão propor. Quanto à etapa da resolução de problemas, a resolução apresentada pelos estudantes é apenas uma parte do processo de resolução, que compreende todo o desenvolvimento dos pensamentos matemáticos dos estudantes que os levam à solução final. Nesse contexto, há de se considerar o registro dos pensamentos matemáticos dos estudantes para melhor compreensão sobre como se desenvolve a aprendizagem matemática durante a resolução de problemas. Já em relação ao desenvolvimento da criatividade dos estudantes ao longo das atividades de proposição e resolução de problemas, ressalta-se a importância de se incluir o desenvolvimento de aspectos formativos como um dos objetivos para as aulas de Matemática. Por último, destaca-se a contribuição teórica desta pesquisa com a comunidade científica na área da Educação Matemática com relação à investigação do desenvolvimento do pensamento criativo dos estudantes durante a etapa de criação de problemas matemáticos.
O PROGRAMA BOLSA-ATLETA: DESENVOLVIMENTO DA PERFORMANCE ESPORTIVA E POLÍTICA DE WELFARE STATE
Authors: Camargo Philipe Rocha de
Published: August 2023

A obra investiga, a partir da análise documental e pela percepção de atletas, se o Programa Bolsa-Atleta, concebido como a uma política de desenvolvimento do esporte de alto rendimento, adquire, ao longo do tempo, a característica de uma política de Welfare no esporte. Em específico, buscou-se: analisar a percepção dos atletas sobre os indicadores apontados pela literatura sobre o processo de Gestão do Programa; analisar a percepção dos atletas se o Programa, por meio das bolsas, atende a função de possibilitar tranquilidade financeira e disponibilidade de tempo para treinar; analisar como o atleta contemplado percebe a implicação do Programa para o desenvolvimento do esporte brasileiro; e analisar, a partir da compreensão dos indicadores de bem-estar social, se os atletas percebem o benefício subsidiado pelo Programa como uma política que afeta outras áreas da vida, além da esportiva, e como/se isso se relaciona à uma política de Welfare State.
Administration safety and occupational risks relationship with job position training quality and needs of medical public health services workforce correlated by political leadership interventions
Authors: Adamopoulos Ioannis Pantelis , Syrou Niki Fotios
Published: August 2023

Background: Workplaces are changing, work exposures are changing, and medical public health workers’ ability to continue doing productive and healthy work is being impacted by social, technical, environmental, economic, and political pressures. This Research has shown the strong link between safety and occupational risks relationship with job position training quality and needs, and their consequences on medical public health services workforce. To determine the severity of the impact as signs of presents a range of threats provides evidence of the perceived risks predictors of these needs, although the sociodemographic characteristics describe the frequency of risk exposure.

Methods: This research is a nationwide study in Greece, construction March to June of 2022. For data collection, a web link was distributed to respondents by email. Providing n=185 responses, safety and occupational risks classification, and were measured with a questionnaire instrument developed, and also a questionnaire developed instrument for measured training needs and quality. ANOVAs one-way test to define variable properties job position, training quality, and training needs correlated by political leadership interventions factor (F).

Results: Chemical risks scores for head of office (median [Mdn]=2.13) were higher to all other job position, χ2= 10.991, p<0.05. Biological risks for head of office (Mdn=3.08) were higher compared to all other categories, χ2=20.770, p<0.01. Psychosocial risks scores for employees (Mdn=3.08) were higher compared to all other categories, χ2=11.349, p<0.05. Organizational risks scores for employees (Mdn=2.84) and head of office (Mdn=2.78) were higher compared to all other categories, and the Kruskal-Wallis test indicated that this difference was statistically significant, χ2(4)=18.278, p<0.01. Perceived training quality 43.78% of participants rate as low (β=0.195, p=0.002), and 65.41% high training needs.

Conclusions: Adding new data to advance the quality of public health services provision organizational support, benefits, resources, and personal protective equipment. Assist in the planning and decision-making phase management provide educational training programs of medical public health workforce to ensure sustainability and optimal performance. There has never been a greater need for trustworthy and unbiased information to assist and guide policymakers, employers, and employees as they go forward.
Detecting and visualizing research trends of blended learning: A bibliometric analysis of studies from 2013-2022
Authors: Chen Huie , Sun Daner , Yang Yuqin , Looi Chee-Kit , Jia Fenglin
Published: August 2023

Blended learning (BL), an innovative, technology-supported pedagogical approach, has been extensively adopted in schools and universities. The learning effectiveness of BL has been investigated in multiple domains of education, computer science, nursing, engineering, and psychology. To uncover the major trends of BL research, this study embarked on a bibliometric analysis of a total of 719 studies published in the recent 10 years (2013-2022) and indexed in the Web of Science core collection. Adopting a quantitative approach and the visual analytical tool of CiteSpace, the review study identified the development trends, the influential researchers and research institutions, and pivotal studies and topics of the field and informed its future progression. The findings revealed a growing trend in BL research in the past decade as reflected in the exponential growth in the number of publications and citations. Charles R. Graham, Chang Zhu, Robert A. Ellis, and Feifei Han were the most prolific, influential researchers in the field, and the Griffith University, the University of Hong Kong, the Vrije Universiteit Brussel, the Monash University, and the National Taiwan Normal University were the prominent research institutions, which engaged in frequent collaborations with others. The United States, China, and Australia were the top-3 contributors to BL research measured by the number of publications, and the studies conducted and reported by researchers in the USA, Turkey, Taiwan, and Spain were cited the most often. Document co-citation analysis unveiled the pivotal studies and topics of the research field, including blended course designs, institutional adoption, achievement, higher education, active BL, flipped classroom, and communication skills.
A study on mathematics students’ probabilistic intuition for decision-making in high school
Authors: Ramírez-Contreras Alejandro , Zúñiga-Silva Leopoldo , Ojeda-Gómez Ezequiel
Published: August 2023

This paper reports on an exploratory study about probabilistic intuition in learning mathematics for decision-making. The analysis was carried out on a group of high school students in relation to their probabilistic intuition in problem-solving, after performing playful learning activities on a simulation platform specifically designed for this study. The analysis used a mixed qualitative-quantitative method. The results showed that the simulation activities facilitated the students’ probabilistic intuition and boosted their performance in solving problems, particularly avoiding decisions based on previous results (when unnecessary) and identifying situations, where binomial distribution can be used.
The impact of using PhET simulation on conceptual understanding of electrostatics within selected secondary schools of Muhanga District, Rwanda
Authors: Uwambajimana Sylvere , Minani Evariste , Mollel Abraham Daniel , Nyirahabimana Pascasie
Published: August 2023

Physics is considered by students as a difficult subject to learn because some physics concepts look like abstracts to students. Electrostatics is the one concept that challenges the students due to its abstract and difficulty to learn. This study aimed to assess the impact of using physics education technology (PhET) simulation on the conceptual understanding of electrostatics within the selected secondary schools of the Muhanga District. A quasi-experimental design was used to investigate the effect of PhET simulations on the conceptual understanding of electrostatics. The study explored the interaction between students and teachers when electrostatics is presented using PhET Simulation. Two groups were used, one group called the control group, which taught by using the traditional method of teaching and the experimental group was taught using PhET simulations. Pre- and post-test were administered to both the control and experimental group. Independent sample t-test results have shown that there was no significant difference in the mean score for the pre-test for both the control and experimental group (p>0.01) while there was a significant difference between the mean score for students in the experimental group and the control group after the intervention. The study used a paired sample t-test to determine whether there is a significant difference in the mean score in the pre- and post-test for the experimental group, the results showed that there is a significant difference in pre- and post-test scores (p<0.01). On the other hand, the observation showed that the interaction between students and teachers increased when PhET simulation was used as an ICT tool. These results show that the use of PhET simulation has an improvement on the conceptual understanding of electrostatics for students taught using this PhET simulation. The study recommends physics teachers use PhET simulation to teach abstract concepts like electrostatics to improve students’ conceptual understanding. Further, they should create an environment, where students can learn difficult concepts with the help of PhET simulation to motivate and engage them for a better conceptual understanding of the concepts.
Synthesis of biodiesel from waste recycled oil employing animal bone ash
Authors: Fabian Chidiebere Ozioko  , David Emoefe Rockson-Itiveh  , Mabel Keke  , Tunde Folorunsho Adepoju
Published: August 2023

In this work, physiochemical properties of the waste used oil (WUO) were carried out for its aptness for biodiesel production. Calcined Animal Bone was used as a bio-base catalyst for the biodiesel production. The produced biodiesel was characterized and the optimum biodiesel produced was determined via statistical analysis using regression analysis. This was with a view to adding value to the waste used oil (WUO) and finding environmentally friendly alternative to fossil fuel. Waste used oil (WUO) was preheated and purified to clean oil via filtration, and the physiochemical and other parameters (cetane number, API, aniline point among others) the cleaned oil were determined using standard methods. The Calcined animal bone was characterized using FTIR, SEM, XRF, BET adsorption, and qualitative analysis. Biodiesel production was done via base catalyst trans- esterification while statistical analysis was done using Microsoft Excel 8.0. In order to ascertain the quality of the biodiesel, the physicochemical properties were determined and the qualities were compared with ASTM D6751 and EN 14214. Results showed that the refined WUO properties were in line with property of oil require for biodiesel production. The physicochemical characteristics of the WUO showed physical state of the oil to be liquid/dark brownish at 28oc, viscosity 6.58 cP at 28 0C, acid value, 0.96 (mg KOH/g oil), FFA (% oleic acid), 0.48, iodine value, 152.00 (g I2/100 g oil), peroxide value, 5.1 milli-equivalent of peroxide/kg of oil among others. The derived catalyst showed high basic strength with Calcium oxide (87.63 wt.%) 0s the dominant element in the catalyst. Optimum biodiesel yield was obtained at run 5 with 98.52 (%wt./wt.) at reaction time of 30 min, catalyst amount of 2.0 (%wt.), reaction temperature of 100 0C, and ethanol-oil molar ratio of 4:1. The produced biodiesel properties conformed to the recommended standard ASTM D6751 and EN 14214. The study concluded that WUO could serve as feedstock for biodiesel production that is environmentally friendly and the derived catalyst could be used as a bio-base in catalytic industries.
The influence of the incoming air velocity with the fan on the inlet side of an air-water generator on the freshwater mass
Authors: Mirmanto Mirmanto  , Made Wirawan  , Gagas Irhami
Published: August 2023

The air-water generator is a promising device to provide freshwater in the future. However, the machine still produces less freshwater; hence, a study of the effect of air velocity with a fan installed at the entrance of a simple air-water generator on the freshwater mass was conducted under environmental conditions. The air velocities varied were 4 m/s, 5 m/s, and 6 m/s. The air-water generator was made from a refrigeration machine system using R134a refrigerant as the working fluid. The compressor specification was 1 PK rotary type. The results show that the highest average freshwater mass obtained is 1241 g for 7 hours, the highest COP was 4.72, and the highest total heat transfer rate is 208.21 J/s.
Genesis hermeneutics: Agar the slave woman who gives a name to god
Authors: Carlos Efraín Montúfar Salcedo
Published: August 2023

Hagar is a woman and a slave, she is also a foreigner, an expatriate and the surrogate of Sara, Abraham's legitimate wife. However, Hagar and later her son Ishmael would underestimate Sara and Isaac, triggering their own escape and exclusion twice into the desert. The text develops a hermeneutic analysis, recognizing that any attempt at interpretation is a principle of dialogue whose objective is reflection on the relationship between the human being (Agar) and God, overcoming all social, ethnic or gender barriers. God exists for the ordinary human because that God is sensitive to his own being, to his own misery. It is the God who sees me, who redeems me, who exempts me from death.
Trends in financing crop production under selected policies, programmes and schemes in Nigeria (1980-2016)
Authors: Nnamdi Ogechukwu Aruocha  , Michael Uchendu Agunannah  , Kingson Njoku
Published: August 2023

The study analyzed trends in financing crop production under financing policies of programmes, institution and schemes in Nigeria from the period 1980- 2016. Specifically the study analyzed the trend in growth rates of selected agricultural financing policies such as the Agricultural Credit Guarantee Scheme Fund (ACGSF) and Agricultural Development Programme (ADP) and crop output; and compared the funds provided by these selected agricultural financing policies. Data were analyzed using trend analysis and z- test, The study showed that crop output and funds provided for crop production under ACGSF and ADP increased overtime within the reference period and were all significant at p<0.01 level. The study shows a compound growth of 5.3% per annum for crop output, 1.8% per annum for ACGSF, and 1.2% per annum for ADP. The study also showed that the growth in crop output and in the financing polices of programmes, institution and schemes were slow. ACGSF significantly allocated more funds for crop production than were done under ADP within the reference period. The study recommends that government should enhance the growth in crop output by ensuring rapid and sustained increase in the allocation of credit for crop production through financing policies of schemes, institutions and programmes. Efforts must be geared towards ensuring that a healthy balance is strike by governments’ financing of crop production through institutions, programmes and schemes.
Microorganisms, proximate analysis, nutritional contents and amino acids profile of naturally opened ackee apple fruits (Blighia sapida)
Authors: Owabumoye J. B.  , Stephen-Amzat B.  , Oyebode J. A.
Published: August 2023

Fruits are important foods that contain nutrients which contribute to the growth and mental health. A total of 100 naturally opened Ackee apple (Blighia sapida) fruits were collected in Ado-Ekiti. The samples were analyzed using standard microbiological techniques examination. The proximate analysis, nutritionally viable minerals contents, and functional properties of the amino acid profile were determined. Fungal isolated were Asperrgillus niger (23 %), Mucor species (11 %), Rhizopus species (15 %) and Aspergillus flavus (35 %) while Bacterial isolates were Bacillus laterusporus (7 %), Staphylococcus aureus (5 %) and Pasteurella sp. (4 %). The sources of microorganisms that contaminated these fruits may include air, birds, insects, rabbits, rats and other animals. The proximate analysis of Ackee Apple Fruits were Ash(3.62 %), Moisture content (40.23%), Crude Protein (5.5 %), Fat (11.55 %), Fibre (3.49 %) and Carbohydrate (35.63%); Mineral contents were Sodium (201.49 mg/100 g), Potassium (652.91 mg/100g), Calcium (8.24 mg/100g), Zinc (258.68 mg/100 g), Magnesium (20.86 mg/100 g), Manganese (0.05 mg/100 g), Iron (7.87 mg/100g) and Phosphorus (48.6 mg/100g); Functional properties were oil absorption (144.5 W/V), Water absorption (378.06 W/V), Foaming capacity (14.50 W/V) and Least gelation concentration (6 W/V) while the amino acid contents ranged from 16 to 132 g/100 g. Crude protein Glutamic acid was the highest Amino acid while Tyrosine was the least. Ackee apple fruits provide nutritive values for health since it contains essential minerals. The health implications of isolated microorganisms are that they can cause mycotoxin and cause food-borne diseases. It is imperative for the consumers of Ackee apple fruits should ensure proper washing and maintain a high standard of hygiene.
Practice of ambulatory surgery: Indications and therapeutic follow-up in the general surgery department at the medical center of Ratoma
Authors: Diawara Mohamed Albert  , Guirassy Mariama II  , Keita Doubany Mariame  , Christophe Maomy
Published: August 2023

Introduction: Ambulatory surgery is a mode of surgical management at the end of which the patient has spent less than 12 hours within the hospital structure, without overnight stay. Our study aims to report our observations on the practice of day surgery, to determine the indications and to identify the therapeutic consequences. Material and methods: This was a descriptive prospective study lasting 6 months from November 01, 2021 to April 30, 2022, on the practice of day surgery in the general surgery department at the medical center. Municipality of Ratoma Results: Out of a total admission of 389 surgical cases, day surgery represented 139 cases or 35.7%. The age group of 16-35 years was dominant 69% or 96 cases with average age of 24.3 ± 10.5 years extreme of age 7 years and 69 years. The male gender was represented in 80 cases, i.e. 61.2%. Pupils and students were the most concerned 71 cases or 51%. Emergencies were the most represented 93.5% or 130 cases. Biology was normal in 116 patients, i.e. 83.4%. 97.8% (n=136) of patients were classified ASAI; 2.1% (n=3) were classified as ASAII. Appendicitis was the most represented operative indication 64% or 89 cases followed by inguinal hernia 17.3% or 24 cases. The majority of our patients 94.2% or 131 cases benefited from general anesthesia and appendectomy was the most practiced surgical technique followed by herniorrhaphy with respective rates of 64% and 17.3%. 100 patients or 71.9% had a duration of intervention between 21 and 30 minutes with an average duration of intervention: 25.6 Minutes ± 6.5 minutes Extreme 18 minutes and 53 minutes. The average duration of hospitalization: 8 hours ± 1.3 hours: Extremes 5 hours and 11 hours. The follow-up was favorable in 116 patients, i.e. 83.5%. The immediate early postoperative complications were present in 23 of our patients, dominated by persistent abdominal pain in 13 patients and those secondary in 03 of our patients including 2 cases of parietal suppuration and 1 case of scrotal hematoma. Conclusion: outpatient surgery is common in our department, practiced much more in young female subjects whose appendectomy is the most performed surgical technique.
A Review on Pharmacological activities and Medicinal properties of Baliospermum montanum
Authors: Samaranayaka Liyanage Gayani Sewwandi  , Rochelle Mangella Peiris
Published: August 2023

Baliospermum montanum which belongs to Euphorbiaceae family is a commonly used plant in both Ayurveda and traditional medicine system in Sri Lanka. It is also known as the “Detta” in Sinhala and “Danti” in Sanskrit. This review aims to provide an overview on pharmacological activities and medicinal properties of Baliospermum montanum. The information was collected from Ayurveda authentic texts, scientific journals and through electronic media. According to Ayurvedic texts roots, leaves, seed and seed oil of Baliospermum montanum are mostly used. According to Ayurveda pharmacological properties of Baliospermum montanum Katu Rasa, Guru Theekshna Guna, Katu Vipāka, Ushna Veerya, Kapha Pitta Shāmaka action. Prabhāva is the purgation. Other medicinal properties are Ashukāri, Vikāsi, Krimihara, Kushtahara, Kaphahara, Vātahara, Dushta Vrana Shōdhana, Udara, Arshōgna, Ashmarihara, Shoolahara, Deepana, Pāchana, Shōdhana, Sara, Ānahahara, Shōpahara, Vidāhahara, Kanduhara, Pleehāhara, Gulmahara and Krimihara. Baliospermum montanum act as purgative. It induces diarrhea and therapeutically it is useful in constipation, anaemia, leucoderma, skin disease, disorders of digestive system, circulatory system, respiratory system, urinary system and skin. Pharmacological actions are Anti-cancer, Anti-microbial, Anti-fungal, Anti-oxidant, Anti-worm, Anti-diabetic, free radical scavenging, immunomodulatory, hepatoprotective, digestive, diuretic, diaphoretic, rubefacient, febrifuge, tonic, anthelmintic, hypotensive, odontalgic, thermogenic, purgative, anodyne, anti-inflammatory, stimulant, anti-dote for snake bite, anti-rheumatic, anti-asthmatic, wound healing, cathartic and anti-dropsical. The present review attempts to encompass the up to date comprehensive literature analysis on Baliospermum montanum with respect to its pharmacological activities and its medicinal properties.
Microfluidic organ-on-a-chip models of human lungs and heart: A review
Authors: Vaishnavi Shivaji Apturkar  , Chaitanya Arvind Gulhane  , Pramod Vitthalrao Burakale
Published: August 2023

A micro-physiological system is another term for an organ-on-a-chip. Due to the idea's widespread use in drug discovery, precision medicine, and drug screening, interest in it has increased recently. The primary message of this article is to illustrate how artificial drug proof can closely imitate the human body in every regard. Important work for a biomimetic system of physiological organs based on a microfluidic chip using cell biology, engineering, and biomaterials technology. In addition, the use and effectiveness of the gut-on-a-chip, liver-on-a-chip, lung-on-a-chip, and heart-on-a-chip are examined. We have discussed the current status of this project, OOC prospects for the future, and opportunities for microfluidic devices and organs on a chip in this section.
Towards sustainable development of urban green space framework in Sorong City, Southwest Papua Province, Indonesia
Authors: Arnold Idie  , Rudi A. Maturbongs  , Jonni Marwa  , Bennidiktus Tanujaya
Published: August 2023

Sustainable development, including efforts to reduce greenhouse gas emissions and strengthen communities' ability to recover back from natural disasters, should inform any increase in urban green space. This study used a survey and interview design based on the Slovin technique and the Likert scale to collect data from members of the impacted community and district, regency, provincial, village, community, traditional, women's, and youth leaders. When asked to rate a sustainable development SDUGS framework, respondents gave 35.25% and 34.29%, respectively, to environmental and social indicators. The next two groups of variables, economic and institutional, came in at 23.84% and 6.62%. Therefore, the respondents endorse the program for the sustainable development of the urban green space model in Sorong City, Southwest Papua Province, with a satisfactory category in the environmental, social, and economic perceptive and a category lacking in institutions whose performance needs to be improved, all in an effort to be in line with the transformation of the Long-Term Strategy for Low Carbon and Climate Resilience by 2050.
Mortality risk factors for tuberculosis patients under treatment in the Kenya health zone, Lubumbashi, DRC
Authors: Yves Givo Katuala  , Tabitha Ilunga Mpoyi  , Tomo Wami  , Adele Daleke Lisi Aluma  , Henri Mundongo Tshamba  , Ben Monga Bondo  , Jean-Baptiste Kakoma Sakatolo Zambeze
Published: August 2023

Context and objective of the study: Tuberculosis remains a major public health problem in the world and in the DRC in particular. Tuberculosis lethality is an important indicator of its control. The objectives of this study were to determine the lethality rate of tuberculosis and to identify the risk factors for death in tuberculosis patients. under treatment in Kenya Health Zone. Methods: This is a case-control study from January 1, 2014 to December 31, 2016. The characteristics of patients aged at least 15 years and who died of tuberculosis during treatment were compared to those who had progressed well. We have exhaustively collected 59 deceased (Cases). The 177 controls were selected according to certain criteria of similarity among tuberculosis patients over 14 years of age who had progressed well. Chi-square tests, Fisher Exact, Wilcoxon, OR and its 95% CI as well as logistic regression were used to analyze our results. For all statistical tests, the significance level was set at 5%. Results: From 2014 to 2016, the rate of overall lethality was3.34% with a decreasing trend. Ihe socio-demographic and anthropometric characteristics: Follow-up care at CST Kalebuka [ORa1.33 (<0.001 - >1000.00), p=0.99],weight loss between the 1st and 2nd phase of treatment [ORa0.94, CI (0.018 - 48.48), p=0.97];clinical and therapeutic characteristics: The concept of counting [ORa1.68, CI (<0.001 - >1000.00), p=0.98],the therapeutic diet2SRHZE/RHZE/5RHE » [ORa>1000.00, CI (<0.001 - >1000.00), p=0.59], irregular compliance with treatment [ORa6.54, CI (<0.001 - >1000.00), p=0.95] did not were not significantly associated with tuberculosis mortality after logistic regression, and therefore constituted confounding factors Conclusion: The decrease in lethality observed during the 3 years reflects a good evolution of the fight. Aprospective study investigating tuberculosis mortality taking into account all possible determinants and aspects will make it possible to identify the factors significantly linked to death and develop additional treatment and follow-up strategiesto further reduce lethality due to tuberculosis.
Ameliorative effects of palm oil on sniper induced toxicity on the cerebral cortex of adult male Wistar rats
Authors: Nkemjika Nnama  , Ezejindu D. N.  , Udodi P. S.  , Agulanna A. E.  , Enemuo I. C  , Okafor E. C.
Published: August 2023

Introduction: Sniper insecticide is a highly toxic, water soluble, synthetic organophosphate belonging to the DDVP (2, 2 — dichlorovinyl dimethylphosphate) compound family of chemicals. It’s wide spread indiscriminate indoor usage and more recently, an effective instrument for suicide related mortality which has been a source of great concern. Red palm oil, on the other hand, is an edible vegetable oil from the fleshy pulp of the oil palm that contains antioxidants; carotenoids that is responsible for its color (pigmentation) and Vitamin E that support brain health. This palm oil is consumed widely, used as an antidote in Nigeria and so is used for various ingested poisons. Aim: This study is aimed at investigating the ameliorative effects of palm oil on sniper induced toxicity on the cerebral cortex. Materials and methods: Sixteen adult male Wistar rats were randomly assigned to 4 groups (n = 4 per group). Group A was the Control, while Group B was administered just sniper (5 mg/kg), Group C was administered 2 ml of Red oil and Group D received 5 mg/kg of sniper + 2 ml of red oil. At the end of the experiment, the rats were sacrificed, their brains extracted and fixed in 10% formal saline for routine histological analysis. Results: There was significant increase in the body weight of Groups A, B, C and D. The relative organ weight of Wistar rats showed an insignificant decrease in the relative brain weight of Group B compared to the Control. Groups C and D also had a relative decrease in comparison to the control. The cerebral cortex reveals neuronal damage and proliferation of glial cells in the sniper-induced group and the mild recovery of neuronal cells in the rats treated with sniper and palm oil. Conclusion: The results from this study shows that there was a significant reduction in organ weight in Group B [Sniper only] when compared to the control group. When palm oil was administered, there was mild recovery of neuronal cells. This shows the ameliorative effects/ impact of Palm Oil in Neurotoxicity.
The analysis of relationship between profitability, liquidity, company size and company values of chemical industry sector manufacturer
Authors: Yanti Budiasih  , Yohanes Indrayono  , Hendro Sasongko
Published: August 2023

The purpose of this study is to ascertain how the value of companies in the chemical industry sector that are listed on the Indonesian stock exchange from 2020 to 2022 is influenced by profitability, solvency, and firm size. This study used Panel Data Regression Analysis, the Classical Assumptions Test, and Multiple Linear Regression Analysis with E-Views 9.0 with a significance level of 5%. The findings of the research indicate that the financial gain (return on equity) does not have an influence on the worth of the company (price-to-book value). However, the ability to meet financial obligations (current ratio) has a negative impact on the worth of the company (price-to-book value). The size of the company does not have any effect on the worth of the company (price-to-book value). Additionally, the financial gain, ability to meet financial obligations, and size of the company all have a simultaneous influence on the worth of the company (price-to-book value). The outcome variable in this research can be clarified by the three independent variables, with an R2 value of 69.14%.
A review on concrete recycling
Authors: Sara Shomal Zadeh  , Navid Joushideh  , Behrokh Bahrami  , Sahel Niyafard
Published: August 2023

Concrete is one the most used material in construction. Considering its capacity to harden upon water contact, solidification, and acquisition of full strength, concrete becomes capable of withstanding significant stress. Over the past century, concrete structures have gained immense popularity and found extensive application in diverse architectural project. This prominence places concrete at the forefront of contemporary design and high-performance structure construction, due to its inherent structural benefits. Consequently, concrete production has witnessed a surge, facilitated by on-site production methods and straightforward construction processes. However, this heightened production has led to a significant generation of concrete waste, reaching up to 80 percent of the original produced volume in some regions worldwide. Recognizing the environmental implications, the reduction of concrete waste through recycling has emerged as a sustainable approach. Extensive research has been conducted to explore methods such as concrete recycling and the incorporation of other waste construction materials into concrete, thereby investigating their effects on concrete properties. This comprehensive review delves into the various material mixtures employed and their implications on the application of recycled concrete.
Effect of competence and compensation on work motivation: Moderation of performance appraisal
Authors: Haposan  , Wayan Gede Supartha
Published: August 2023

Effective public services hinge on adept human resource management in government, yet challenges persist. Chief among them is the lack of employee motivation and competence, impacting service quality. Bolstering work motivation and competence is crucial, alongside fair compensation and unbiased performance evaluations. Recognizing and harnessing employee motivation is key for optimal public service. This study delves into how performance appraisal moderates the effects of competence and compensation on work motivation in ASN employees of Balai Besar Pelaksanaan Jalan Nasional Jawa Timur – Bali in Bali Province. Employing a quantitative approach, the research explores the interplay between competence, compensation, performance appraisal, and work motivation. Targeting ASN employees within the specified unit, the study employs saturated sampling, yielding 92 respondents. Data collected through questionnaires undergoes Moderated Regression Analysis (MRA) using IBM SPSS Statistics 25, following classical assumption tests. Findings reveal the positive impact of competence on work motivation; enhancing competencies heightens motivation. Similarly, higher compensation positively influences work motivation. Surprisingly, performance appraisal does not moderate the effects of competence or compensation on work motivation. Competence, compensation, and performance appraisal collectively shape individual work motivation within the organization. In conclusion, enhancing public service quality requires addressing employee motivation and competence issues. The study underscores competence and compensation as vital drivers of work motivation, while indicating a limited role for performance appraisal moderation. Elevating these aspects can substantially enhance public service efficiency and efficacy, benefiting both government bodies and the communities they serve.
Optimization of the learning of English grammar in secondary students in Ecuador through the use of technology at level A1
Authors: Rossula Amarilis Martillo Ochoa
Published: August 2023

There is a real need to improve the grammatical knowledge of students in such a way that they can state their ideas in a foreign language and build complete sentences. An important aspect to consider when teaching adolescents is the motivation that technology provides. One possibility of delivering the motivational resource and meeting the learning needs of students concerning grammar can be the use of materials in which students have to resort to technology. (López, & Rodríguez, 2023) Analyzing how technological support can strengthen grammatical accuracy in eighth-grade students of the Basic General Education (EGB Superior) teaching-learning process is necessary. To achieve the objective, the research followed the mixed method that includes collecting or examining quantitative and qualitative information simultaneously or consecutively. Mixed methods provide a complete picture by recording trends, generalizations, and insight into the participants' points of view. (Wang, & Chang, 2023) Technology offers a variety of interactive tools and resources that can help students learn and practice grammar more effectively and at their own pace. In addition, using technology can increase students' motivation and engagement with language learning, improving their overall performance. (Vargas, & Gómez, 2023)
Evaluation of blood glucose, hepatic biomarkers and histopathology of alloxan induced diabetic rats fed Sesamum indicum compounded diet
Authors: Kelechi Light Ekeke  , Kizito Munachiso Iheanacho  , Chiamaka Perpetua Nzebude  , Divine Obichukwu Anakor  , Geraldine Obumneme Udebunu
Published: August 2023

This study was aimed at evaluating the blood glucose level, hepatic biomarkers and histology of alloxan induced diabetic rats fed with Sesamum indicum compounded diet. Thirty-Six male albino rats were divided into nine groups (normal control, diabetic control, standard drug-glibenclamide treated, diabetic rats fed with 15%, 30% and 60% Sesamum indicum compounded diet and normal rats fed with 15%, 30% and 60% Sesamum indicum compounded diet and induced with diabetics after 14 days) of four rats each and the study lasted for 21 days. The induction of diabetes was done by a single dose of freshly prepared alloxan (120 mg/kg b.wt.) given intraperitoneally. The level of blood glucose was determined using Acu-check glucometer while the hepatic biomarkers was determined using standard spectrophotometric method. The blood glucose of the groups fed with the diet were observed to reduce when compared with the diabetic untreated group. Significant (p<0.05) reduction was observed for the hepatic biomarkers when compared with diabetic control. From the histopathology of the liver, the results showed improved liver for the groups fed with the compounded diet when compared with the diabetic control group that showed a damaged liver. The results of this study have shown that Sesamum indicum has both protective and ameliorative effect on blood glucose, hepatic biomarkers and restore the distorted liver of a diabetic rat.
Interaction study of 5- Fluorouracil with Bovine serum albumin by UV-Visible spectrophotometry
Authors: Sajna John  , Gopika VC  , Sadiyath mol VP  , Arun K Johnson  , Abu salah KS  , Anoop PJ  , Mohammed Jasil
Published: August 2023

Introduction: 5-Fluorouracil (5-FU) is primary chemotherapeutic drug used for most colorectal, pancreatic and aggressive forms of breast cancers. Serum albumin is major carrier protein and its binding with drugs is important to examine the change in pharmacokinetic properties which directly influence the bio availability, sustained drug release and toxicity of drugs. Aim and objectives: The aim of the project is to perform a study on interaction of 5 - fluorouracil with bovine serum albumin employing the UV-Visible spectrophotometric method. Methods: Interaction of 5-FU with BSA has been studied systematically using UV spectroscopy by fixing the carbonate buffer of pH 7.4 as solvent and at a suitable wavelength 230 nm and 275 nm. To gain an insight into the interaction of 5-FU with BSA, the spectra of the 5-FU and BSA were examined in the absence and presence of various concentrations of the 5-FU and BSA respectively at zero minutes and repeated in 30 minutes, 60 minutes and 90 minutes time interval. The changes in peak intensity, absorbance and shift in peaks were observed. The detectable differences were recorded. This method can be used successfully for the interaction study of 5-FU with BSA. Results: Interaction study of 5-Fluorouracil with bovine serum albumin revealed that appreciable changes in absorbance, peak area and shifts in peak were observed which may be due to binding of drug with protein BSA.
Cycling and the physiological effects
Authors: Mariana de Paula  , Maria Gisele dos Santos  , Richard B. Kreider
Published: August 2023

Cycling is a physical activity that has been practiced for a long time in Brazil and in the world since the appearance of the vehicle called the bicycle, and since the mid-nineteenth century, people have already noticed some remnants of the benefits that pedaling could offer to man. At the beginning of the history of the bicycle it was used for various purposes related to the means of transport and, over time, it was recognized as a physical activity and even as a sport. The term cycling as “the art of pedaling” and “the sport of bicycle racing”, because initially shortly after its creation, the bicycle was considered a means of transport of noble refinement that was restricted to the male figure. Over time, women were conquering their space and overcoming prejudices about their participation in the modality.
Current status of cannabis regulation in Morocco
Authors: Soukaina BENNIS  , Majda HEDDATE  , AMAL AIT HAJ SAID
Published: August 2023

Cannabis sativa L. is known for its psychotropic properties as well as therapeutic benefits, which have been exploited since ancient times. These are due to molecules synthesized within the plant known as cannabinoids, with tetrahydrocannabinol (THC) being responsible for the main effects. These products have significant therapeutic advantages related to relieving nausea and vomiting, as well as stimulating appetite. Recent evidence clearly demonstrates analgesic and antispasmodic effects that will prove clinically significant. The global regulatory landscape regarding the medical use of cannabis is rapidly evolving, as seen in the case of Morocco, which has given the green light for cannabis use through the adoption of a new law, 13.21, that will regulate the entire production chain by establishing a national regulatory agency. It is within this context that our work is framed, with the primary objective is to providing an overview of the new cannabis regulation in Morocco. This regulatory framework will oversee all operations related to cannabis use, from production to commercialization