bluuebunny/crossref_metadata_2025 huggingface dataset:
Piggybac-mediated stable expression of NGN2 in iPSCs for differentiation into excitatory glutamatergic neurons v2
Authors: Dou Dan , Alexander Boecker C.
Published: March 2024

We adapted a previously-described method (Pantazis et al., 2022) for employing Piggybac transfection to stably express doxycycline-inducible NGN2 in human iPSCs. After stable integration of NGN2, proceed to differentiate iPSCs using protocol “iNeuron differentiation from human iPSCs.”
Metabarcoding Fecal Swabs or Stomach Contents for Fish and Crustaceans using 2-PCR protocol and Illumina MiSeq v1
Authors: Wisely Eldridge
Published: March 2024

This protocol describes a method to metabarcode a 170bp region of the mitochondrial16S rRNA gene of crustaceans and a 163-185bp region of the mitochondrial 12S rRNA gene of fishes. These regions are subjected to PCR separately in multiple replicates and the resulting PCR products are pooled by sample and then indexed for sequencing on an Illumina MiSeq platform.
The Effect of Students Social Interaction on Their Learning Motivation During Distance Learning to Modeling and Building Information Design Program (MBID) Students at Public Vocational High School (PVHS) in Bandung
Authors: Islami Intan Salamah Nur
Published: March 2024

Thesis with the title “The Effect of Students Social Interaction on Their Learning Motivation During Distance Learning to Modeling and Building Information Design Program (MBID) Students at Public Vocational High School (PVHS) in Bandung” is a research during distance learning that observe about students social interaction and their learning motivation in case of MBID program students at PVHS in Bandung. Distance learning performs with online and offline learning that be adapted by government regulations of pandemic learning situation. Its impact the change of social interaction on learning process as online learning from home and offline learning at school with Covid-19 protocol. This change is during distance learning involve students interaction would change with their teachers, their parents, and the other students. It can affect the students learning motivation, to their intrinsic and extrinsic motivation. This thesis is using quantitative method by questionnaire spread with likert scale, it’s analyzed with compare means and simple regression analysis. The result is indicate the students social interaction and their learning motivation in a good category with each means score 3.75 and 3.76, it also points there is effect of students social interaction on their learning motivation with the value until 63.7%.
The Effect of Student's Interpersonal Communication Skills On Student's Learning Outcomes In Mechanical Engineering Subjects
Authors: Sukarna Tasya Fatihah
Published: March 2024

The differences in student’s background, cognitive, language learning, motor skills, talents and readiness cause the difference of their communication skills. By knowing the different abilities that exist in students, teachers will likely be able to provide learning in the right way. This study was conducted to determine how much the effect of student’s interpersonal communication skills on student’s learning outcomes in Mechanical Engineering subjec. There are 96 samples in this study which also the students of X DPIB 1,2,3 SMK Negeri 2 Garut. The test of student's interpersonal communication skills is a research instrument that author developed, while student’s learning outcomes are seen from the final score of Mechanical Engineering subject on the even semester of 2020/2021 school year. The data analysis technique that used in this study is an aproach of correlation, determination, and simple linear regression analysis. Based on regression analysis, the results showed that there was a positive and significant effect on student’s interpersonal communication skills on student learning outcomes in Mechanical Engineering subject. It means that the better the student’s interpersonal communication skills, also the better their learning outcomes in Mechanical Engineering subjects.
The Contribution of Online Assistance for Student Learning Outcome During Distance Learning to The Technical Drawing Subject at Public Vocational High School 6 (PVHS 6) in Bandung
Authors: Adila Mutiara , Permana Asep Yudi , Yosita Lucy
Published: March 2024

Abstract – The Minister of Education and Culture of the Republic of Indonesia has issued a Circular Letter Number 4 of 2020 concerning the Implementation of Education Policy in the Emergency Period of Coronavirus Disease (Covid-19) that teaching and learning activities are carried out from home. Learning in distance is a solution from the government to execute learning activities then they can continue to run during the pandemic period, by utilizing the online media. Distance learning also occurs in productive subjects in vocational high schools, such as technical drawing subject. The technical drawing subject during distance learning is limited by time, even though this technical drawing subject requires a very long time because it requires quite high accuracy. Thus online assistance became one of the solutions to guiding students outside the technical drawing hour’s lesson during distance learning through online media such as computer, television, radio, telephone, internet, video, etc. Assistance usually with face-to-face, one of its aims is helping the learning process of students who are having difficulty of understanding the material and build students to achieve the learning goals, but during distance learning assistance is carried out online. The obstacles found in the online assistance, they are the students’ devices, teachers’ communication with students, teachers are difficult to drawing checking, and students are difficult to understand the material. The method used in this research is a quantitative descriptive method with a number of samples is 46 involve the class of first grade students in Modeling and Building Information Design Program (MBID) at PVHS 6 in Bandung. Data collection techniques use two ways, they are questionnaire techniques with a 39 number of questions grains on online assistance variables and documentation techniques on learning outcomes by referring to student’s value on the task of the technical drawing subject. Before data analysis, an instrument test was using the validity and reliability test. Then, perform the analysis of the level of respondents to find out the general description of the variables. Furthermore, data analysis was carried out by the normality test, correlation test, regression test, and hypothesis test. The results of the research obtained were known that the achievement level of online assistance with fairly good category. Also the achievement level of students learning outcome with fairly good category. While the acquisition of online assistance contribution to learning outcomes is 9% by determination analysis and the correlation coefficient is equal to 0.300 which means the relationship category is weak. Therefore, the hypothesis (Ha) is accepted, there are positive contributions between online assistance to learning outcomes.Keywords – Online Assistance, Technical Drawing, Learning Outcome, Distance Learning.
DEVELOPMENT OF A VOCATIONAL SKILLS TRAINING MODEL FOR CONSTRUCTION WORKERS
Authors: Widaningsih Lilis , Rahmanullah Fauzi , Megayanti Trias , Kusuma Yudhistira , Susanti Indah
Published: March 2024

The development of culture and technology in responding to human needs in architecture and physical infrastructure development requires an acceleration in the skills of construction workers. Many factors become obstacles for construction workers to be able to compete and improve their skills. One of them is access to education and skills training because of the lack of information and opportunities they can get. This study aims to develop a vocational skills training model oriented to the certification of skilled workers in the construction industry. The development of the training model is made through stages that refer to research and development of Logic Model Development. The process carried out includes the planning, implementation, analysis, testing and finalization of the training model. Data collection was carried out through surveys of construction worker service users, FGD with training model development experts, FGD with construction industry stakeholders, theoretical analysis, and policies as materials for model development. The findings of this study are in the form of a training model that develops networks and collaborations between institutions related to skilled workers in the construction industry. Vocational universities have the potential to strengthen and facilitate construction workers in improving job skills and certifying skilled workers. In the long term, this model is expected to become a prototype for a sustainable vocational skills training system for construction workers.
IDENTIFYING THERMAL COMFORT OF TROPICAL ARCHITECTURAL CONCEPT BUILDING : A CASE STUDY OF EXPANDABLE HOUSE
Authors: Cung Rickie , Rosetia Amanda
Published: March 2024

Tropical architecture is an architectural building concept that focuses on the use of materials and techniques used in an accordance with the environment and climate in the tropical region. Buildings with tropical architectural style have special characteristics in adapting to climate conditions, but currently there are also modern buildings that can be categorized as contemporer tropical buildings. In the context of Batam city, contemporer tropical architectural buildings have not been prominent, especially in residential houses applications. Moreover, few residential houses failed to follow thermal comfort in the objective of Batam climate. This study aims to identify the elements of thermal comfort in residential houses which apply contemporer tropical architectural concepts in the city of Batam. In this case the author examine “Rumah Tambah” as a case study. By conducting a literature review and comparison of case studies as well as direct observation to the location, this research was conducted using an inductive qualitative method using primary and secondary data. Finally, this research produces an identification of thermal comfort that is applied to residential houses with a contemporer tropical architectural concept and provides recommendations for design elements in residential houses with a contemporer tropical architectural concept in the city of Batam.
REVITALIZATION OF SPORTS HALL TUMENGGUNG ABDUL JAMAL BATAM WITH SUSTAINABLE BUILDING APPROACH
Authors: Ariansyach Hary Budhi , Rangkuty Gladies Imanda Utami
Published: March 2024

Sports organizations are receiving more and more requests to lessen the detrimental effects of venues and activities held on the environment as the green environment movement continues to spread quickly throughout the world. With the widespread appeal of professional sports across cultural divides, leading Teams' embrace of pro-environment activities also has the ability to spur good social change among fans and spectators. One of the best ways to revitalize a historic area is to give the buildings a new use in addition to their previous one. Redevelopment of a location that can enhance the area's functionality is referred to as revitalization. The goal is to raise the value of the land or location. The revitalization of Sports Hall Tumenggung Abdul Jamal aims to revive the image of Sports Hall with a Sustainable Architecture approach where buildings or assets will be maintained as the identity of the city and provide life activities that benefit the community so that economic value is obtained that ensures the building is maintained and the benefits of use can be felt by the wider community.
Effect of Daily Stress on School Adjustment among Children at Community Child Centers: Mediating Roles of Inattention and Social Withdrawal
Authors: Lee RaeHyuck
Published: March 2024

Background: This study verifies the influence of daily stress on school adjustment through inattention and social withdrawal among children at community child centers.Methods: Analyses were performed on data collected from the Child Panel Survey of the Community Child Centers, followed by a series of regression analyses.Results: First, daily stress had a negative and significant influence on school adjustment. Second, both inattention and social withdrawal among children mediated the influence of daily stress on school adjustment. Finally, the influence of daily stress on school adjustment was serially dual-mediated through inattention and social withdrawal.Conclusions: This study presents evidence-based strategies that could help the school adjustment of children at community child centers.
Clinical and laboratory substantiation of the effectiveness of professional oral hygiene in preparation for orthopedic treatment with the use of fixed structures of dentures
Authors: Lepilin Alexander V. , Zakharova Natalya B. , Martynova Maria  I. , Konnov Valeriy  V. , Erokina Nadezhda L.
Published: March 2024

ВACKGROUND: To extend the service life of fixed orthopedic structures of dentures, professional oral hygiene (POG) should be conducted before orthopedic treatment based on changes in the cytokine profile in the gingival fluid.
АIM: To assess the nature of changes in the cytokine profile in the gingival fluid during orthopedic treatment with the use of fixed denture structures before and after the POG.
MATERIALS AND METHODS: The patients (n=30) were divided into three groups of 10 people each: group 1, patients with intact periodontitis; group 2, patients with mild periodontitis; and group 3, patients with moderate periodontitis. The examination was conducted before the installation of fixed orthopedic structures and before and a week after POG. Six mediators of immunoregulatory processes — interleukin-6 (IL-6), interleukin 1-beta (IL-1ß), tumor necrosis factor alpha (TNF-α), chemokines (IL-8, MCP1), and vascular endothelial growth factor (VEGF) — were quantified in J samples by solid-phase enzyme immunoassay.
RESULTS: In patients with inflammatory periodontal diseases, a high IL-1ß, IL-6, IL-8, MCP1, and VEGF content was found in gingival fluid compared with the group of examined individuals without inflammatory periodontal diseases. After POG, a decrease was found in the content of the main proinflammatory cytokines/chemokines in the blood and the level of VEGF in patients with inflammatory periodontal diseases.
CONCLUSION: A decrease in proinflammatory cytokines, chemokines, and VEGF in gingival fluid after the POG procedure leads to the blockade of inflammatory and destructive processes in periodontal tissues and allows the introduction of personalized practice of preparing supporting teeth in the oral cavity for permanent prosthetics.
Comorbidity of periodontal diseases and atopic dermatitis
Authors: Donskaya Olga S. , Berdnikova Ekaterina I.
Published: March 2024

BACKGROUND: The relationship between periodontal diseases and somatic pathology has been proven. Studies on the link between periodontal and atopic diseases are few, which determines the relevance of this study.
AIM: To characterize the relationship between inflammatory periodontal diseases and atopic dermatitis.
MATERIALS AND METHODS: Overall, 26,470 full-text publications from 2016 to 2023 on the research topic were found in the databases PubMed, Google Scholar, and eLIBRARY.RU.
RESULTS: An analysis of literature data was performed to study the relationship between inflammatory periodontal diseases and atopic dermatitis. On the one hand, the presence of oral pathology in patients with atopic diseases can lead to atopic disease worsening, and on the other hand, an atopic disease can contribute to the development of oral diseases. After conducting a literature search and applying the inclusion and exclusion criteria for the sample, complete overlap of the research topics was found in three publications. The data obtained were contradictory, as two publications established a direct connection between periodontitis and atopic dermatitis and one publication did not. In studies on the research topic on certain aspects, the possible mechanisms of comorbidity of periodontal and atopic diseases are characterized and assessments on the existence of a feedback or direct relationship between these pathologies are presented.
CONCLUSION: The periodontal status of patients with atopic dermatitis remains poorly understood, and evidence linking oral diseases to it is ambiguous. The presented studies relatively confirmed the direct connection between periodontal diseases and atopic dermatitis; however, the hygiene hypothesis, that is, there is an inverse relationship between periodontal diseases and atopic diseases, was not confirmed.
Polymorphisms of genes of interleukin-6 and alpha-1 chain of collagen type 1 in postmenopausal women with knee osteoarthritis
Authors: Ignatenko Grigory A. , Reznichenko Natalia A. , Fedulichev Pavel N. , Maylyan Eduard A. , Kharaeva Zaira F.
Published: March 2024

BACKGROUND: To date in the Russian Federation insufficient attention has been paid to the study of IL6 and COL1A1 gene polymorphisms role in the development of knee osteoarthritis. And the results of the single carried out to date studies, devoted to the research of polymorphic variants of the above genes influence on the osteoarthritis development, are insufficient for substantiated conclusions.
AIM: To study the frequency of alleles and genotypes of the IL6 gene rs1800795 polymorphism and COL1A1 gene rs1107946 and rs1800012 polymorphisms in postmenopausal women with knee osteoarthritis.
MATERIALS AND METHODS: The results of 157 postmenopausal women survey with knee osteoarthritis were selected and analyzed. The control group consisted of 326 women of the same age without signs of joint disease. The study of polymorphisms rs1800795, rs1107946 and rs1800012 was performed by real-time polymerase chain reaction.
RESULTS: The conducted studies showed that in the general group of examined women the frequency of all three studied polymorphisms genotypes registration corresponded to the Hardy-Weinberg law. An uneven (p = 0.043) distribution of rs1800795 polymorphism genotypes was found in the group of women with osteoarthritis and in the control group in the study of the IL6 gene polymorphic variants frequency detection. This difference was due to more frequent GG genotype registration of the above polymorphism (odds ratio = 1.75; 95% confidence interval: 1.12–2.72; p = 0.021) among women with knee osteoarthritis. Associations of rs1107946 and rs1800012 COL1A1 gene polymorphisms were not found (p 0.05).
CONCLUSIONS: An association between GG genotype of the IL6 gene rs1800795 polymorphism and knee osteoarthritis in postmenopausal women has been established. Genotypes and alleles of COL1A1 gene rs1107946 and rs1800012 polymorphisms were not associated with joint disease.
Gap junction protein connexin-43 and its distribution in different tissues
Authors: Filippov Mikhail S. , Korzhevskii Dmitrii E.
Published: March 2024

Connexins is the family of proteins which in vertebrates form gap junctions – intercellular contacts allowing the passage of small molecules between cells. Connexin-43 is the most abundant member of connexin family in human. Its cellular functions are diverse, and its localization in the human body is the most wide across all connexins. Most intensive research is devoted to the investigation of соnnexin-43 role in intercellular communication and its functional features in the vital organs — heart and brain. Due to high abundance in different tissues, at the moment there is the large amount of various experimental data, which are hard to assemble into global picture. This work aims to present generalized information about the distribution and functions of соnnexin-43 in various tissues and further prospects for studying this protein using the currently available literature data.
Öğrencilerin Gözünden Sosyalleşme Alanları: Aidiyet Hissi ve Psikolojik İyi Oluşun Anahtarı
Authors: Yılmaz Cansu , Çiftçi Houghton Esma Esen
Published: March 2024

Bu araştırmanın amacı, üniversitelerdeki sosyalleşme alanlarından duyulan memnuniyetin, öğrencilerin kendi birimlerine (fakültelerine) olan aidiyet hissi ve psikolojik iyi oluşları ile ilişkilerini araştırmaktır. Öğrencilerin, birimlerindeki sosyalleşme alanlarından yüksek düzeyde memnuniyet duymalarının daha yüksek düzeyde aidiyet hissiyle ilişkili olması ve böylece daha yüksek psikolojik iyi oluş skorları raporlaması beklenmektedir. Bu amaç doğrultusunda, 549 üniversite öğrencisi (Ortyaş = 21.20, SSyaş = 3.32) çevrimiçi bir ölçek çalışmasına katılmıştır. Katılımcılar, kendi birimlerindeki sosyalleşme alanlarından duydukları memnuniyeti değerlendirmiş ve ayrıca aidiyet hissi ve psikolojik iyi oluşlarını ölçen ölçekleri doldurmuştur. Sosyalleşme alanlarından duyulan memnuniyet ile psikolojik iyi oluş arasında doğrudan bir ilişki gözlenmemiştir. Ancak öğrencilerin sosyalleşme alanlarından duydukları memnuniyet, kendi birimlerine olan aidiyet hissini artırma yoluyla dolaylı olarak daha yüksek psikolojik iyi oluş düzeylerini yordamıştır. Bu sonuçlar öğrencilerin yaşları, cinsiyetleri, sınıf düzeyleri kontrol edildikten sonra da anlamlılığını korumuştur. Bu çalışma, tek bir büyük üniversite örneğine dayanmasına rağmen, bulguların hem akademisyenler hem de uygulamacılar için önemli tartışma konuları sunabileceğini vurgulamaktadır.
John Locke'un Tartışmalı Yönü: İngiltere Ulusal Köle Ticaretindeki Rolü
Authors: Gokcekuyu Ertugrul
Published: March 2024

Klasik liberalizm ve liberalizm çalışmalarında, John Locke öncü düşünürler arasında ilk akla gelen isimlerden biridir. Locke'un liberal düşünceleri günümüzde birçok demokratik toplumda kabul görmektedir. Ancak, Locke'un Batı literatüründe bilinen ve buna nispeten akademik literatürümüzde daha az karşılaşılan tartışmalı bir yönü de vardır: bu da onun yaşadığı dönemde İngiltere'nin ulusal köle ticaretinde aktif rol almasıyla alakalı tartışmalardır. Bu makalenin gayesi Lock’un eserlerinde yer alan kölelik ile alakalı yazılarını ve bu konunun alan yazınında söylemsel açıdan nasıl ele alındığını ortaya koymaktır. John Locke’un fikirleri ve eserleri günümüz siyaset bilimi alanında temel kaynak olarak kabul görürken, özgürlük, eşitlik ve insan hakları gibi fikirleriyle de en çok okunan ve bilinen siyaset felsefecileri arasında yer aldığı gerçeğidir. Ancak, Locke'un bilinmeyen bazı yazıları, özellikle kölelik konusundaki görüşleri, tartışmalara neden olmuştur. Locke, özünde özgürlük ve mülkiyet haklarına vurgu yapan bir siyaset felsefecisi olarak bilinir, ancak Locke köleliği meşrulaştırdığı iddiasıyla da eleştirildiği bilinmektedir. Locke'un, on yedinci asırda Virginia Kolonisinde kölelik olgusunun yasallaştırılması sürecinde katkıda bulunduğu şeklindeki tartışmalar, onun yazdığı liberal düşünceleri ile doğrudan çatışmaktadır. Bazı düşünürler Locke'un ‘Two Treaties of Government’ adlı eserinde bulunan kölelik ile alakalı yazdığı kısımların, köleliği haklı göstermek adına argüman olarak yazıldığı iddiasıdır. Buna karşın, karşı duruş sergileyen bilim insanları ise Locke'un köleliği desteklemediğini ve hatta köleliğe karşı çıktığını savunmaktadırlar. Onlara göre, Locke, insanların doğal haklarının korunması ve devletin meşruiyetiyle ilgili fikirlerinde kölelik karşıtı bir tutum sergilediği şeklindedir. Bu makale, Locke'un liberal düşünce ekolünde bir otorite olduğu kadar, yapılan eleştirilerin de onun yaşadığı dönem itibariyle ciddiye alınması gerekliliği üzerine kurulmuştur.
Göç, Kentleşme ve Ekonomik Büyümenin Suç Üzerindeki Etkisi: Seçilmiş OECD Üyesi Ülkeler Üzerine Bir Uygulama
Authors: Aydın Fatma Fehime , Levent Cemalettin
Published: March 2024

Ülkelerin karşı karşıya kaldığı en önemli sosyo-ekonomik sorunlardan biri suç olgusudur. Bu nedenle suça neden olan ve suç oranını etkileyen faktörlerin incelenmesi önem arz etmektedir. Bu bağlamda bu çalışmada suç üzerinde etkili olduğu düşünülen göç, kentleşme ve ekonomik büyüme faktörlerinin suç üzerindeki etkilerinin ekonometrik olarak araştırılması amaçlanmaktadır. Bu amaçla çalışmada öncelikle literatür taraması yapılmış, ardından seçilmiş 11 OECD üyesi ülkenin 1990-2021 verilerinden yararlanılarak yatay kesit bağımlılığı ve homojenite testleri uygulanmıştır. Daha sonra CIPS birim kök testi, Westerlund eşbütünleşme testi, Dumitrescu-Hurlin panel ve ülkeye özgü nedensellik testleri, en küçük kareler yöntemi ve robust en küçük kareler yöntemi uygulanmıştır. Çalışmada elde edilen bulgulara göre kentleşme suça neden olurken suç da göçe neden olmaktadır. Ayrıca Almanya ve Japonya’da göçün suçun nedeni olduğu, Kosta Rika, Almanya, Hollanda ve İsveç’te suçun göçün nedeni olduğu; Meksika, Avustralya, Almanya ve İspanya’da kentleşmenin suçun nedeni olduğu, Japonya ve İspanya’da suçun kentleşmenin nedeni olduğu; Kolombiya’da ekonomik büyümenin suçun nedeni olduğu, suçun ise hiçbir ülkede ekonomik büyümenin nedeni olmadığı tespit edilmiştir. En küçük kareler yöntemi ve robust en küçük kareler yöntemi sonuçlarına göre, göç değişkeninin suç oranlarını azalttığı, kentleşme ve ekonomik büyüme değişkenlerinin ise suç oranlarını artırdığı görülmüştür.
A Contribution of Social Work to the Discourse on the Theory-Practice Relationship
Authors: Demir Ali
Published: March 2024

The question of the theory-practice relationship is one of the core questions of philosophy and the social sciences. How should the proportions between theory and practice best be determined? Social work joins this discourse from a logic of applied sciences. It can develop an appropriate answer that can be generalized if it first participates on that discourse. For that, the theory-practice relationship is first distinguished from the theory-practice proportion. Because while a proportionality points to communication, which could be determined vertically in one way, in the case of the relationship is horizontality at the centre of the debate, which refers to the consent of the other actor. Therefore, the following paper will first distinguish the philosophical question of how the relationship between knowledge and action should be determined from the sociological question of how the proportion between knowledge and action is in a given profession. After an introduction, the genesis of the theory-practice communication the question is put what can be deduced from this distinction for social work. Depending on the viewpoint, the relationship can either be transformed into communication through mediation between theory and practice, or theory can be separated, decoupled from practice. In a third proposal developed here, this theory-driven relationship and/or proportion can be viewed from the logic of theory-practice complementarity.
Examination of Provinces in Türkiye about Sectoral Employment Share by Cluster Analysis
Authors: Bitgen Sungur Banu , Madenoğlu Fatma Selen
Published: March 2024

The significance of regional dynamics in the process of economic development and regional development has increased as a result of significant factors like competitiveness, human resource development, and observation of the global market. In this study, mathematical programming-based cluster analysis has been conducted to group the regions in Türkiye according to sectoral employment rates. A mixed integer mathematical model is presented that maximizes the smallest of the out-of-cluster distances while minimizing the largest within-cluster distance. Level 2- 26 sub-regions in Türkiye are clustered according to sectoral employment data for 2021 and 2022. As a result, two clusters were obtained for both years in our country according to employment status by gender on a sectoral basis. One of these clusters is where the employment rate of the agricultural sector is higher than other sectors, and the other is where the employment rate of the industrial and service sectors is higher. When the 2021 and 2022 clusters are compared, in total, TR22, TR32, TR33, TRC3; in men, TR21, TR22, TR32, TR52, TR81; In women, it was observed that TRC1 regions were assigned to different clusters. By implementing a successful employment policy as human resource development across the national government, it will be possible to ensure the balanced growth of provinces located in Türkiye's various geographical areas.
A Comparative Analysis of the Translator’s Identities of Robert Morrison and Yan Fu in Two Chinese Translations of the Bible
Authors: Xian Huixin
Published: March 2024

The Bible, as a classic work of Christianity, holds an important position in the world literary history, and its translation into Chinese has been a difficult and complicated process. This paper selects two Translators Robert Morrison and Yan Fu, as well as their Chinese translations of the Bible as the research objects. Through a comparative analysis of the cultural identities of these two translators, the paper elucidates the influence of different translator identities on their translation behavior. The study found that based on different cultural identities, Morrison and Yan Fu presented different emphases in terms of the text selection and different translation characteristics of the two Chinese translations of the Bible.
Human papillomavirus genotype distribution among colposcopy diagnosed cervical precancerous lesions
Authors: Sultana Fahmida , Tabassum Mishkat , Jakanta Faika M. , Dev Anamica , Haque Kazi S. , Aktar Mossa N. , Sharmin Shah N. , Nessa Ashrafun
Published: March 2024

Background: Cervical cancer (CC) is one of the primary causes of gynaecological cancer death. Cervical cancer is the fourth most frequent cancer worldwide, and it is the second most common cancer in Bangladesh. The stage of cervical cancer at diagnosis has a significant impact on survival. Cervical cancer mortality is high in Bangladesh due to late detection and limited management facilities. The aim of the study was to determine the pattern of human papillomavirus (HPV) genotype among colposcopy diagnosed cervical precancerous lesions.
Methods: This cross-sectional study was conducted in the department of gynecological oncology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka. Total of 142 women attending the colposcopy clinic of BSMMU.
Results: The mean age was found 38.7±7.3 years with a range from 30 to 60 years. 10 (7.0%) patients were found HPV 16 positive followed by 1 (0.7%) HPV 18, another hr-HPV 3 (2.1%), HPV 16 and other hr-HPV 3 (2.1%) and HPV 16, HPV 18 and other hr-HPV 1 (0.7%). Regarding colposcopy reports 99 (69.7%) patients had CIN I, 33 (23.7%) had CIN II and 10 (7.0%) had CIN III identification by colposcopy reports. 61 (43.0%) patients had CIN I followed by 15 (10.6%) had CIN II, 11 (7.7%) had CIN III, 7 (4.9%) had CIS, and 48 (33.8%) had normal or squamous metaplasia by histopathological reports.
Conclusions: It can be concluded that among all the 14 hr-HPV genotype HPV 16 is more prevalent while HPV18 prevalence was very low in colposcopy diagnosed cervical precancer cases. The study revealed HPV16 was more common among high grade lesions.
Prevalence of menstrual disorders and self-care practices among female undergraduates in a southwestern tertiary institution, Nigeria
Authors: Ayamolowo Love B. , Ayamolowo Sunday J. , Olayinka Esther O. , Olowokere Adekemi E.
Published: March 2024

Background: Menstrual health, crucial for women's well-being, often remains obscured by misconceptions, stigma, and limited awareness. This study aimed to assess menstrual disorder prevalence and self-care practices among female undergraduates.
Methods: Using a descriptive cross-sectional design, we surveyed 216 female undergraduates through a structured questionnaire, employing multistage sampling. Data underwent Chi-square and logistic regression analysis (5% CI).
Results: Dysmenorrhea (81.9%), amenorrhea (41.7%), menorrhagia (30.6%), and irregular cycles (30.5%) were predominant menstrual disorders. Self-care was practiced by many during menstruation, including pain medication (50%), heat application (38.9%), and exercise (29.2%). Nonetheless, 59.7% lacked awareness about self-care practices. Age (p<0.05, OR=7.07, CI: 0.75–66.90), educational level (p<0.05, OR=2.75, CI: 0.76–10.01), knowledge level (p<0.05, OR=0.67, CI: 0.22–2.02), and education sponsor (p<0.05, OR=3.44, CI: 0.56–21.22) were linked to menstrual disorders, highlighting the need for menstrual hygiene product access.
Conclusions: This study identified high menstrual disorder prevalence and urges awareness and education for proper self-care. Tailored interventions by policymakers, educators and healthcare providers can empower women, enhancing menstrual health outcomes.
Female pelvic floor myofascial syndrome and its relationship with lower urinary tract storage symptoms
Authors: Leyva Vazquez José I. , Guerrero Reyes Guadalupe , Gutiérrez González Adrián , Hernández Velázquez Ricardo , Loya Maldonado Karen M. , Treviño Cavazos Omar , Reyes Alcaraz Jennifer E. , Robledo Torres Alejandra , Saca Cuevas Sara Y. , Herrera Morales Juan C.
Published: March 2024

Background: Pelvic floor myofascial syndrome is defined as non-articular skeletal muscle pain, characterized by the presence of trigger points. Present in 14-23% of patients with chronic pelvic pain. It has an impact on urinary function. The prevalence of lower urinary tract symptoms is 15-67%, with storage symptoms predominating in patients with PFMS. Objective was to determine the relationship between female pelvic floor myofascial syndrome and lower urinary tract storage symptoms.
Methods: This was a retrospective, observational, descriptive, cross-sectional, homodemic and single-center study at University Hospital Doctor José Eleuterio González, Monterrey, Nuevo Leon, Mexico from period one from April 1st to June 30th, 2022. Type of non-probabilistic convenience sampling. Database in Excel 2016, Pearson's Х² statistical test in the SPSS V25® program.
Results: 136 patients with PFMS and LUTS storage were evaluated. The most frequent age group was 46-55 years with 33.1% (N=45); the marital status was married with 74.3% (N=101). In relation to education 55.9% (N=76) with a bachelor's degree. The most frequent storage symptoms were nocturia 67.6% (N=92) p<0.05, frequency 60.3% (N=82) p=0.512, urgency 57.4% p<0.005.
Conclusions: Knowing the correlation between PFMS and storage LUTS can guide specific pain treatment with review of urinary symptoms. In patients with nocturia, frequency, urgency, SUI and UUI, a physical examination should be performed and included trigger points in the pelvic floor. Nocturia is the most prevalent storage LUTS in PFMS.
Maternal near miss: a retrospective study in a tertiary care hospital at South India
Authors: Sengodan Subha Sivagami , Mallesh Tejashwini
Published: March 2024

Background: A maternal near miss (MNM) case is defined as a woman who nearly died but survived a complication that occurred during pregnancy, childbirth or within 42 days of termination of pregnancy. MNM situations tend to mirror the causes of maternal death. Hence, review of these cases has been found to help in the assessment of maternal health services. These cases are called as MNM or severe acute maternal morbidity (SAMM) and auditing these cases is called near miss audit (NMA).
Methods: A retrospective study of 201 MNM cases over a period of 12 months from January 2023- December 2023. Demographic data were collected from MNM review form and records. Data studied and analyzed.
Results: There were 11,340 deliveries and 11,126 live births during the study period out of which 201 MNM cases were studied. Haemorrhage followed by anemia was the most common cause of near miss events. The most common age group affected in the near miss cases in the present study was 20 to 35 years (80%). Majority of the cases were referred from the nearby PHCs and government hospitals.
Conclusions: Most maternal deaths are preventable by optimal utilization of existing MCH facilities, identifying the bottleneck in health delivery system, early identification of high-risk pregnancy and therein timely referral to tertiary care centre.
Clinico-histopathological study of gonadal and extragonadal teratomas in tertiary care centre
Authors: Topiwala Fatema , Gorade Jyoti , Siddiqui Marium , Bhat Dharitri , Deshpande Archana
Published: March 2024

Background: Teratomas are quite often seen in the gonadal region. As compared to gonadal teratoma extragonadal teratomas are very rare. They can be mature, immature, malignant or mixed germ cell tumor. Many a times they are missed clinically because of their rare locations that include retroperitoneum, sacrococcygeal, mediastinum, thyroid, eye, ear, and mesentery. In such locations the list of clinical differentials is long and it is difficult for the clinicians to make an accurate clinical diagnosis. Aims of the study were: to identify the different locations of extragonadal teratoma, to know the histological types of teratoma in different location, and to correlate histopathological diagnosis and clinico-radiological diagnosis.
Methods: It is an observational descriptive study of histopathologically proven teratomas over a span of 2 years from July 2021 to July 2023.
Results: Out of total 35 cases of teratomas, we had received 14 cases of extragonadal teratomas. The most common sites being sacrococcygeal region. They were most common in the paediatrics age group and most common sex involvement was of male.
Conclusions: While interpreting the histopathological findings, a high index of suspicion for teratomas needs to be kept even if the site is not a gonadal location. Simple excision is a cure for this condition or else it may transform to malignancy.
Pregnancy outcome in women with bacterial vaginosis
Authors: Das Snehangshu , Basanti Namoijam , Singh Ajitkumar , Kulnu Neiketouzo
Published: March 2024

Background: Bacterial vaginosis is a condition characterized by alteration in the vaginal flora. It is a common occurrence during pregnancy and is one of the established risk factors for preterm delivery, premature rupture of membranes and chorioamnionitis. The objective of the study was to study the prevalence and effects of bacterial vaginosis during pregnancy.
Methods: : The study was a hospital based prospective study conducted in the department of obstetrics and gynaecology, RIMS, Imphal from January to December, 2021. 250 women between 20-28 weeks of gestation underwent examination and testing for bacterial vaginosis and were followed up till delivery. Pregnancy outcomes like pre-term labour, premature rupture of membrane; fetal outcomes like birth-weight, APGAR score, NICU admission, or any other complications were noted.
Results: Out of the 250 singleton pregnancies, 48 women (19.2%) were found to have bacterial vaginosis. Pregnancies associated with bacterial vaginosis had more chances of premature rupture of membranes, low birth weight babies. But, there was no significant association of the same to preterm labor and to the rate of NICU admission of the newborns.
Conclusions: Vaginal infection during pregnancy should also be entertained seriously and treated well since bacterial vaginosis may directly or indirectly be related to preterm delivery and low birth weight babies.
A comparative study of intrapartum epidural analgesia with intramuscular tramadol on labor outcome
Authors: Basit Syed , Khan Nowsheen , Bano Annum
Published: March 2024

Background: Epidural analgesia produces analgesia in labour without affecting nervous system, allows the mother to be well oriented, fully conscious and alert throughout labour. The aim of this study is to study the effect of epidural analgesia and intramuscular (IM) tramadol in different stages of labour and compare the effect of epidural analgesia with intramuscular tramadol on progress of labour and its outcome.
Methods: Continuous monitoring of the haemodynamic parameters of the mother was done using multiparameter monitors. Foetal monitoring was done using continuous cardiotocography (CTG) monitor. Primigravida in spontaneous labour were randomly divided into two groups. Group I received epidural analgesia and group II received IM tramadol.
Results: Duration of Ist stage of labour in group I was 167.0±47.2 min and in group II was 214.4±50.2 min. Mean duration of III stage of labour in the present group I was 7.9 min and 7.5 min in the group II. In the present study, total duration of labour is shortened by 47 min in group I compared to group II.
Conclusions: Epidural analgesia during labour is a simple and effective method for painless and safe delivery. Analgesia produced by epidural route is significantly more effective than intramuscular tramadol. Epidural analgesia has favourable effect on the progress of labour. In developing nations where availability of facilities is the main limiting factor, intramuscular tramadol which is a safe and satisfactory drug for relief of labour pain, can be considered as a suitable alternative.
A comparative study of episiotomy suturing using suture material chromic catgut versus Rapide Vicryl and its outcome
Authors: Ruge Trupti , A. Lathasri
Published: March 2024

Background: Episiotomy is a surgical incision which is made in the perineum to enlarge the vaginal opening for birth, with a purpose to facilitate the completion of the second stage of labour to improve both the maternal and the neonatal outcomes. A significant number of women experience perineal trauma following vaginal deliveries which may result in perineal pain, dyspareunia and faulty healing. The type of suture material which is used, will influence these factors. Objectives were to assess the effect of suture materials (Rapide Vicryl versus catgut) used in episiotomy and evaluate the wound healing characteristics on day 2 and day 7.
Methods: All the pregnant women in labour admitted in labour room of Navodaya medical college, 200 patients satisfying the inclusion and exclusion criteria were taken and were assigned in one of the groups for episiotomy and suturing was done using either of the materials-Vicryl Rapide 2-0 or chromic catgut 1-0, followed up the women in the postnatal ward on day 2 and day 7 and look for immediate complications of episiotomy like temperature, severe pain, hematoma induration, wound gapping and discharge.
Results: Among a total of 200 cases, at 48 hours, there was no significant difference according to the pain measurement scores, but the median consumption of analgesics was significantly lower with fast-absorbing polyglactin 910. There was no difference in the association with dysparenia at 6 weeks after the delivery between chromic catgut (19%) compared with standard polyglactin 910 group (8%).
Conclusions: Fast-absorbing form of polyglactin sutures are preferred over chromic catgut because of their non- allergic properties, increased tensile strength, lesser probability of pain and lower chances of infection.
Effect of maternal body mass index on pregnancy outcome: a retrospective observational study at a secondary level care hospital in India
Authors: Ghosal Adrija , Rashmi  , Akhtar Selim , Das Bibekananda , Bhattacharya Tushar Kanti
Published: March 2024

Background: Maternal BMI outside the range of 18.5 to 24.9 is associated with adverse maternal and/or foetal outcome. In India, due to extreme socioeconomic distribution, double burden of malnourishment & obesity is being observed, though it varies from state to state. Many studies are conducted showing association of obesity with pregnancy outcome, while importance of underweight is not studied frequently in our geographical area, hence this study was planned to be conducted.
Methods: Our aim was to evaluate the maternal and perinatal outcomes in patients belonging to different BMI categories. We performed retrospective observational study at department of obstetrics and gynaecology, Suri Sadar Hospital, a secondary level care hospital at Birbhum, West Bengal, India between July 2021 to May 2022. Sample size taken was 170. Detailed data were collected from the MCP card (maternal child protection card) of the mothers, antenatal follow up sheets of these women and hospital medical records. The study participants were then divided into 5 groups according to their first trimester BMIs. Statistical analysis was carried out with the help of Micro soft Excel and Epiinfo 7.1 software, p<0.05 were considered significant.
Results: Average mean weight gain in our study was 9.1118 kg and we found significant association between weight gain during pregnancy & BMI status (p<0.001). We also observed significant association of gestational diabetes mellitus, preeclampsia, caesarean section, pre-term labour, post-partum haemorrhage, post-partum wound infection with obese & overweight mother. FGR and MAS were also found to be significantly associated with maternal BMI. Complex maternal metabolic environment on developing foetus in obese mother alone or complicated by PIH or GDM may be the cause. In underweight mother, malnutrition and micronutrient deficiency may lead to development of FGR.
Conclusions: Pre conceptional normal BMI is essential for every woman willing to conceive. Nutrition-sensitive programs like food security, poverty alleviation, women education, women empowerment, dietary consultation for all newly married couples is required for developing countries to prevent altered pre pregnancy BMI.
Study to analyse the intraoperative and post-operative complications of total abdominal hysterectomy and total laparoscopic hysterectomy
Authors: Yadav Gunjan , Verma Meenal
Published: March 2024

Background: Laparoscopic hysterectomy is preferable due to faster recovery, decreased morbidity and absence of an abdominal incision. The aim of the study was to compare the risks and complications of total laparoscopy hysterectomy and total abdominal hysterectomy in terms of intra-operative and post-operative complications.
Methods: A retrospective observational study was conducted in the Gynaecology department at Department of Obstetrics and Gynecology, Central Railway Hospital, Jabalpur, Madhya Pradesh, India. The data for the past 2-year record was taken for analysis. A total of 72 subjects were included in the study and were divided into two groups with 36 patients under TAH (total abdominal hysterectomy) group and 36 under TLH (Total Laproscopic hysterectomy) group. The primary outcome of the present analysis were incidence of perioperative complications like blood loss and the secondary outcomes were operating time, blood loss, urinary tract injury, rate of conversion to laparotomy, postoperative pain, and length of post operative stay.
Results: The mean intra-operative blood loss was measured among both the groups and it was found to be very high among TAH group (215 ml) compared to TLH group (124 ml) and the difference was found to be statistically significant (p<0.05). Similarly, the duration of operative procedure was found to be less in TLH group (46.5 mins) compared to TAH group (76.8 mins) and the difference was found to be statistically significant (p<0.05). Post-operative wound infection (14 vs 0) was found to be more among the patients in TAH group than that of the TLH group and the difference was found to be statistically significant (p<0.05).
Conclusions: TLH is a safe and effective surgical treatment for benign gynaecological diseases and should be offered whenever possible, taking into account the low rate of complications and cost-effectiveness.