bluuebunny/crossref_metadata_2025 huggingface dataset:
Do it yourself or send for help? Considering specialty referral from a general practitioner perspective
Authors: McKenzie Brennen
Published: January 2024

General practice veterinarians (GPs) are often faced with the question of which services they should provide themselves and which are more appropriately the province of board-certified specialists. The growing availability of specialty care, the expectations of many pet owners for advanced care resembling that which they receive, the expanding availability of new and more technologically sophisticated interventions, and many less easily defined shifts in the economic and cultural context of veterinary medicine all add to the pressure to limit services in general practice and refer more patients to specialists. However, the criteria for making decisions about referral are often ill-defined and controversial. Furthermore, most GPs are trained by specialists in secondary or tertiary care institutions, providing them with a perspective that may not reflect the realities of the general practice environment.While each referral decision for a specific patient must be made in the unique context of that case, reflection and discussion concerning relevant general principles can help GPs build a rational foundation for making such decisions. The principles and methods of evidence-based medicine and the expanding concept of a spectrum of care can usefully inform decision-making about referral. It is also critical that all stakeholders contribute to discussion of these questions and to the training of veterinarians so that the next generation will be prepared to shape and embody the role of GP in a manner that best meets the needs of patients, pet owners, and veterinarians themselves.
Analysis of the Use of Agile Methods, Tools and Techniques in Foundry Enterprises
Authors: Pacana Andrzej , Czerwińska Karolina
Published: January 2024

In an increasingly volatile environment, the importance of agile management, which should be based on flexible procedures and agile strategy, is increasing. The purpose of the study was to analyze the trend of development, level of knowledge and implications with the application of agile methods, techniques in project, program and manufacturing process management tools, as well as to identify areas of activity of foundry companies in the context of increasing the efficiency of their operations through the use of agile project approach. The completed research indicated that the knowledge and variety of application of agile methods, tools and techniques is at a relatively low level within the framework of project, program and manufacturing process management in the surveyed foundries. Among the most commonly used instrumentation are: PDCA, Kanban, SCRUM, SCRUMBAN, Lean Development, DMAIC and XP. The research showed that the use of agile instrumentation in the areas of projects, programs and manufacturing process management allows work to be done in an orderly and transparent manner. Foundries that consistently use agile instrumentation produce high-quality and non-conformity-free products with short time-to-market. Future research directions will be to perform a comparative analysis of the level of knowledge and implications of agile instrumentation in foundries located in Poland and selected neighboring countries.
Optimizing Supply Chain in a Foundry Through Computer Simulation Using Flexsim – A Case Study
Authors: Krynke Marek
Published: January 2024

The article presents the optimization of supply chain management in a foundry using computer simulation with the FlexSim program. The authors analyze collaboration with external entities in the production process, focusing on the settlement of raw materials, transportation services, and storage costs. Special attention is given to the production plans of subcontractors integrated into the operational production schedule. Utilizing the 3D FlexSim environment, they showcase a simulation model optimized for minimizing the costs of production, transportation, and storage of alloying elements essential for iron casting production. The case study illustrates the effective use of computer simulation in refining supply chain management within the context of the foundry production process.
Health-Promoting Food Labelling – Benefits and Drawbacks
Authors: Radziejowska Maria
Published: January 2024

This work systematizes the knowledge on several food labelling systems, namely the Nutri-Score, the NutrInform, and the Mediterranean Index (Med Index). The Nutri-Score system assesses nutritional value of a product per 100 g or 100 ml with no consideration of usually consumed serving as well as vitamins, minerals, and bioactive compounds. The concept of NutrInform does not label food products as ‘good’ or ‘bad’. Instead, it indicates energy content in a serving (50 or 100 g) and contents of individual nutrients in a serving along with the percentage of their reference values of recommended daily intake. Thus, the NutrInform label placed on a product by a manufacturer participating in the system presents information in the following order: energy content in calories, contents of fatty acids, saturated fatty acids, sugars, and salt (everything expressed in grams). The Med Index covers three pillars of sustainability, taking into account nutritional, environmental, and social aspects. This labelling system assesses 27 criteria (9 for each pillar), the presence or absence of which is immediately visible to the consumer by a different colour of a label on the front of the pack (where blue reflects to the best score). A single graphic symbol allows consumers to simultaneously analyse various properties of the product and/or its production process in a few seconds. It forms a useful tool for comparing food products belonging to the same category and a useful system for ending the information asymmetry that characterizes the market of many food products. In our opinion, the concept of the Med Index would be the most useful considering health-promoting labelling of food products in Poland.
On the Role of Image Processing Techniques in the Quantitative Image Analysis
Authors: Gądek-Moszczak Aneta
Published: January 2024

The article explores how qualitative image analysis impacts the process of image interpretation, particularly in composite microstructure analysis. It highlights the importance of high-quality images for accurate computer-based object detection, emphasizing the limitations of rigid pixel-based rules compared to human visual perception. The study underscores the need for optimal imaging conditions to avoid image defects that hinder precise computational analyses in scientific and industrial applications.
Risk Management in Manufacturing Practice Using the Point Method
Authors: Žitňák Miroslav , Korenko Maroš , Shchur Taras , Kiełbasa Paweł , Kazán Ľuboš , Mazur Magdalena
Published: January 2024

This study delves into the critical process of risk management within manufacturing environments, emphasizing its role as a perpetual cycle influencing all organizational tiers. The research primarily addresses the identification, analysis, and mitigation of risks in specific occupational roles within a manufacturing company. A comprehensive risk assessment is conducted for these roles both pre and post the introduction of safety protocols. The study's practical application showcased a substantial diminishment of occupational risks, particularly highlighting a 46.37% reduction in the toolmaker-milling role. This significant decrease underscores the efficacy of the implemented safety measures and the importance of continual risk management in maintaining a safe and productive work environment.
PENERAPAN ESKUL KEAGAMAAN UNTUK MENGEMBANGKAN BAKAT SISWA DI SDIT AD - DAUD PALARAN SAMARIND
Authors: Nurul Hikmah
Published: January 2024

Education that only puts intellectual intelligence in reality is not enough as a provision in life. Having broad intellectual intelligence is a must-have obligation, because intellectual intelligence is a provision in the face of the development of the era. However, intellectual intelligence alone is not enough, because the ideals of Indonesian ancestors not only have broad intellectual intelligence. However, it is also a dignified nation, which has a noble character of ethics accompanied by religious values as a fortress in the students. The formation of religious characters can be done in various ways, one of them conducting religious activities at school, ranging from religious exclusions, Koran, training lectures and others. From this activity later the character of the students began to be well formed, who can not pay so can do the Koran, the rare prayers can be diligent prayers because in the school is required prayer in congregation depending on how we form the character of the student itself. Until later a good character will be brought by students to their neighborhood. The subject of this study is a class VI student of AD-DAUD Palaran, while the research object is the application of religious esules to develop talent. The data collection techniques used are observations, interviews and documentation. The study used the Miles and Huberman analysis model. Miles and Huberman, said that activities in the analysis of qualitative data are conducted interactively and continue continuously until complete, so that the data has been saturated.

Keywords: Extracurricular, Religious, Talent
Implementasi Dakwah Bil Hal dalam Program Posdaya Berbasis Mesjid di Desa Purwamekar Kabupaten Karawang
Authors: Rohmah Firda Aulia
Published: January 2024

Implementasi, Dakwah Bil hal, Program posdaya
Uji Efektivitas Diuretik Kombinasi Rebusan Rimpang Alang-alang (Imperata cylindrical L.) dan Daun Kumis Kucing (Orthosiphon aristatus Benth.) pada Mencit Jantan (Mus musculus)
Authors: Fadillah Andi , Rusdiaman Rusdiaman , Stevani Hendra
Published: January 2024

Rhizomes of reeds (Imperata cylindrical L.) and leaves of kumis Kucing (Orthosiphon aristatus Benth.) are traditional medicines used as diuretics. The flavonoids contained in these two plants have biological activity as a diuretic. In this study, 15 mice were separated into 5 groups, each containing 3 mice as test subjects. Group 1 was given aquadest. Group 2 was given furosemide 20 mg/kg BW, boiled reeds with a concentration of 60%: 40% cat's whiskers leaves was given to group 3, reed rhizome decoction with a concentration of 50%: 50% cat's whiskers leaves was given to group 4, and group 5 was given reed rhizome decoction with a concentration of 40%: 60% cat whiskers leaves. The treatment group was studied for 4 hours and the volume of urine was recorded every 30 minutes. The results of the study showed that boiled cat's whisker leaf alang-alang rhizomes from the third concentration group had a diuretic effect where the mice excreted urine for the first time in the 60th minute. The group showing positive controls and negative controls excreted urine for the first time at 30 minutes.
Keywords:          Diuretics, reeds, cat whiskers, mice
 
Abstrak
Rimpang alang-alang (Imperata cylindrical L.) dan daun kumis kucing (Orthosiphon aristatus Benth.) merupakan salah satu obat tradisional yang digunakan sebagai diuretik. Flavonoid yang terkandung dalam kedua tanaman inilah yang mempunyai aktivitas biologis sebagai diuretik. Pada penelitian ini, 15 ekor mencit dipisahkan menjadi 5 kelompok yang masing-masing berisi 3 ekor mencit sebagai subjek uji. Kelompok 1 diberikan akuades. Kelompok 2 diberikan larutan furosemide 20 mg/kg BB, rebusan alang-alang dengan konsentrasi 60% : 40% daun kumis kucing diberikan pada kelompok 3, rebusan rimpang alang-alang dengan konsentrasi 50% : 50% daun kumis kucing diberikan pada kelompok 4, dan kelompok 5 diberikan rebusan rimpang alang-alang dengan konsentrasi 40%: 60% daun kumis kucing. Kelompok perlakuan tersebut diteliti selama 4 jam dan dicatat volume urin tiap 30 menit. Hasil penelitian menunjukkan bahwa rebusan rimpang alang-alang daun kumis kucing dari ketiga kelompok konsentrasi memiliki efek diuretik dimana mencit mengeluarkan urin pertama kali pada menit ke-60. Kelompok mencit kontrol positif dan kontrol negatif mengeluarkan urin pertama kali pada menit ke-30.
Kata Kunci:         Diuretik, alang-alang, kumis kucing, mencit
Uji Efektivitas Patch Ekstrak Daun Sirih Hijau (Piper betle L.) pada Penyembuhan Luka Sayat Punggung Kelinci (Oryctolagus cuniculus)
Authors: Aini Dewi Nurul , Ningsih Dwi , Pramukantoro Ganet Eko
Published: January 2024

Betel leaf (Piper betle L.) has potential as wound healing. The purpose of this research is formulate green betel leaf extract into patch with good stability and physical quality, knowing green betel leaf extract has healing effect, determine the concentration green betel leaf extract which is effective in healing cut wounds. Development in patch form due to the advantages, namely therapeutic effect, practical, and comfortable. The patch formula using extract concentrations 2%, 6%, and 10%. Patches are tested for physical quality, stability checks, and determination of active substance content. Observations effectiveness of wound healing were carried out every day before giving treatment including wound length, healing time, erythema, edema, degree of dryness, scab, and pus. Data wound healing were analyzed with Kruskall-Wallis and Mann Whitney. The results showed that green betel leaf extract could be formulated into a patch with good physical quality and stability. Green betel leaf extract 2%, 6%, and 10% has wound healing effect. The concentration of extract that effective as wound healer is 6%.
Keywords:          green betel leaf, extract, patch, wound healing
 
Abstrak
Daun sirih hijau (Piper betle L.) memiliki potensi sebagai penyembuh luka sayat. Tujuan penelitian ini adalah untuk memformulasikan ekstrak daun sirih hijau dalam bentuk patch dengan mutu fisik dan stabilitas yang baik, mengetahui ekstrak daun sirih hijau memiliki efek penyembuhan luka sayat, mengetahui konsentrasi ekstrak daun sirih hijau yang efektif dalam menyembuhkan luka sayat. Pengembangan dalam bentuk patch karena memiliki kelebihan yaitu efek terapi lama, praktis, dan nyaman digunakan. Formula patch menggunakan konsentrasi ekstrak yaitu 2%, 6%, dan 10%. Patch diuji mutu fisiknya, pemeriksaan stabilitas, dan penetapan kadar zat aktif. Pengamatan efektivitas penyembuhan luka dilakukan setiap hari sebelum pemberian perlakuan meliputi panjang luka, waktu penyembuhan, eritema, edema, tingkat kekeringan, keropeng, dan nanah. Data pengamatan penyembuhan luka dianalisis menggunakan SPSS Kruskall-Wallis dan Mann Whitney. Hasil menunjukkan ekstrak daun sirih hijau dapat diformulasikan ke dalam bentuk sediaan patch dengan mutu fisik dan stabilitas yang baik. Ekstrak daun sirih hijau dengan konsentrasi 2%, 6%, dan 10% memberikan efek penyembuhan luka sayat. Konsentrasi ekstrak yang efektif sebagai penyembuh luka sayat yaitu 6%.
Kata Kunci:         daun sirih hijau, ekstrak, patch, penyembuhan luka sayat
Uji Aktivitas Antioksidan Wedang Uwuh dengan Variasi Formula Jenis Jahe dan Waktu Penyeduhan
Authors: Winasih Puri Anggit , Supriyadi Supriyadi , Turahman Taufik
Published: January 2024

Wedang Uwuh is a well-known traditional health drink from Imogiri, Bantul and Yogyakarta. Ginger is one of the components of wedang uwuh. In Indonesia, ginger comes in three different varieties: red, emprit, and elephant ginger. The aim of this study was to identify the best ginger varieties for wedang uwuh, as well as the ideal brewing period that would yield the most antioxidant activity. After being identified, each plant in the wedang uwuh recipe was brewed in boiling water for 10, 20, and 30 minutes. By using TLC and a test tube, the water wedang uwuh steeped was identified as flavonoids and phenols. The DPPH method was employed in this study's antioxidant activity test. Wedang uwuh containing red ginger brewed for 10 minutes has higher antioxidant activity compared to elephant and emprit ginger, with an IC50 value of 27.73 µg/mL. The Friedman test results on the examination of the type of ginger and the brewing time wedang uwuh was brewed on IC50 obtained p = 0.000 where p<? (0,05). This demonstrates that the brewing time and kind of ginger used in wedang uwuh have an impact on the IC50 value.
Keywords:          Antioxidant, ginger, wedang uwuh, DPPH
 
Abstrak
Wedang Uwuh adalah minuman kesehatan tradisional khas Imogiri, Bantul dan Yogyakarta. Salah satu bahan wedang uwuh adalah jahe. Ada tiga jenis jahe di Indonesia: jahe gajah, merah dan emprit. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antioksidan terbaik dari wedang uwuh dengan variasi jenis jahe dan waktu penyeduhan yang paling tepat untuk wedang uwuh agar menghasilkan aktivitas antioksidan paling tinggi. Semua tanaman dalam formula wedang uwuh dideterminasi kemudian diseduh menggunakan air mendidih selama 10, 20, dan 30 menit. Air seduhan wedang uwuh diidentifikasi flavonoid dan fenol dengan KLT dan uji tabung. Uji aktivitas antioksidan yang digunakan dalam penelitian ini adalah metode DPPH. Wedang uwuh dengan kandungan jahe merah yang diseduh selama 10 menit memiliki aktivitas antioksidan lebih tinggi dibandingkan dengan jahe gajah dan emprit, dengan nilai IC50 27,73 µg/mL. Hasil uji friedman pada analisis jenis jahe dan waktu penyeduhan wedang uwuh terhadap IC50 diperoleh p = 0,000 dimana p<? (0,05). Hal ini menunjukkan bahwa ada pengaruh jenis jahe dan waktu penyeduhan wedang uwuh terhadap nilai IC50.
Kata Kunci:         Antioksidan, jahe, wedang uwuh, DPPH
Formulasi Tablet Paracetamol Menggunakan Pati Biji Durian (Durio zibethinus Murr) Sebagai Bahan Pengikat Secara Kempa Langsung
Authors: Sipatu Yayuk Susanti , Ani Nur
Published: January 2024

Research has been carried out on the formulation of paracetamol tablets using Durian Seed Starch (Durio Zibethinus Murr) as a binder by direct compression to determine the most effective concentration of binder. This research method uses qualitative methods. The results showed that the average percentage of solute in paracetamol tablets in formulas I, II, and III were 88.3215%, 67.2974%, and 31.5981%, respectively. The results indicated that formula I with a binding agent concentration of 8% met the requirements in the Indonesian Pharmacopoeia, while formulas II and III (10% and 12%) did not meet the specified requirements. The test results for the physical properties of the tablets showed that all formulas met the requirements for size uniformity, weight uniformity, friability, and tablet hardness. While statistical tests using Ansira (Ragam Sidik Analysis) showed that the use of durian seed starch as a binder at concentrations of 8%, 10%, and 12% had no significant effect on the physical properties of the tablets.
Keywords: Paracetamol Tablets, Durian Seed Starch, Binders, Direct Felt.
Abstrak
Telah dilakukan penelitian tentang formulasi tablet paracetamol menggunakan Pati Biji Durian (Durio zibethinus Murr) yang berfungsi sebagai bahan pengikat dan menggunakan tekhnik kempa langsung dengan tujuan untuk menentukan konsentrasi bahan pengikat yang paling efektif. Metode yang digunakan pada penelitian ini yaitu metode kualitatif. Hasilnya menunjukkan, jumlah persen rata – rata zat terlarut tablet paracetamol untuk formula I,II dan III berturut-turut 88,32 %, 67,29 % dan 31,59 %. Hasil penelitian tersebut menunjukkan bahwa pada formula I menggunakan konsentrasi bahan pengikat 8% memenuhi persyaratan dalam Farmakope Indonesia, sedangkan pada formulasi II dan III (10% dan 12%) tidak memenuhi syarat yang ditentukan.  Hasil uji sifat fisik tablet menyatakan bahwa semua formula memenuhi persyaratan keseragaman ukuran, keseragaman bobot, kerapuhan dan kekerasan tablet.  Sedangkan uji statistik dengan menggunakan Analisis Sidik Ragam menunjukkan bahwa penggunaan pati biji durian sebagai bahan pengikat pada konsentrasi 8%, 10% dan 12% mempengaruhi sifat tablet yang sebenarnya.
Kata Kunci: Tablet Paracetamol, Pati Biji Durian, Bahan Pengikat, Kempa Langsung
Penentuan Kandungan Fenolik Total Kombinasi Ekstrak Etanol Daun Jeruk Purut (Citrus hystrix) Dan Daun Kelor (Moringa oleifera L.)
Authors: Qonitah Fadilah , Ariastuti Reni , Kusumasari Jihan Aulia
Published: January 2024

Kaffir lime leaves and moringa leaves are known to contain phenolic compounds that can have potential as antioxidants. The purpose of this study was to determine the total phenolic content of the combination of ethanol extracts of kaffir lime leaves and moringa leaves. Preparation of extracts was done by maceration method using 95% ethanol. Determination of total phenolic content by colorimetric method using Folin-Ciocalteu reagent and gallic acid as standard. The results showed that the largest total phenolic content in the combination of J:K extract (1:0) was 3.58 ± 0.09 %EAG while the smallest phenolic content in the combination of J:K extract (0:1) was 1.32 ± 0.08 %EAG.
Formulasi dan Uji Stabilitas Fisik Krim Tabir Surya Nanoenkapsul Ekstrak Daun Ubi Jalar Ungu (Ipomoea batatas L.) Varietas Antin-3
Authors: Hasbiah Siti Nur , Apriyana Alycia Eka Putri , Dipahayu Damaranie
Published: January 2024

UVA and UVB sunlight can damage skin tissue. The flavonoids and polyphenols in purple sweet potato (Ipomoea batatas L.) leaf extract of the Antin-3 variety nanoencapsulated was able to absorb the intensity of UV light so that can be used as an active ingredient for sunscreen cream preparations. The aim of this research is to examine the effect of variations Antin-3 leaf extract nanoencapsulated were 0.3% : 0.6% : 0.9% [F1:F2:F3] on the physical stability using a mechanical and freeze thaw test (3 cycles,48 hours for each cycle). Mechanical test results show that all of the formula were not separated. The freeze and thaw test result show that the differences of variations nanoencapsulated Antin-3 leaf extract had not affect for the color, aroma and homogeneity, type of cream (water in oil type) and pH value but had an influence for the spreadability value. The best formula that can be chosen is F3 because it had the highest concentration of Antin-3 leaf extract nanoencapsulated. It is necessary to reformulate by increasing the concentration of consistency stabilizer agent.
Keywords:          Sunscreen, nanoencapsulation, Antin-3, freeze thaw, mechanical test
 
Abstrak
UVA dan UVB sinar matahari mampu merusak jaringan kulit. Flavonoid dan polifenol dalam nanoenkapsulasi ekstrak daun ubi jalar ungu (Ipomoea batatas L.) varietas Antin-3 mampu menyerap intensitas sinar UV sehingga dapat dijadikan bahan aktif untuk sediaan krim tabir surya. Tujuan penelitian ini adalah untuk mencari pengaruh variasi kandungan nanoenkapsulasi ekstrak daun Antin-3 yaitu 0,3% : 0,6% : 0,9% [F1:F2:F3] terhadap stabilitas fisik mekanik dan freeze thaw (3 siklus, per siklus 48 jam). Hasil uji mekanik menunjukkan bahwa ketiga formula tersebut tidak memisah. Hasil uji freeze and thaw menunjukkan bahwa perbedaan variasi nonoenkapsulasi ekstrak daun Antin-3 tidak mempengaruhi warna, aroma dan homogenitas, tipe krim minyak dalam air dan nilai pH namun memberikan pengaruh terhadap nilai daya sebar. Formula terbaik yang dapat dipilih adalah F3 karena memiliki konsentrasi nanoenkapsulasi ekstrak daun Antin-3 paling tinggi. Perlu dilakukan reformulasi dengan meningkatkan konsentrasi bahan penstabil konsistensi.
Kata Kunci:         tabir surya, nanoenkapsulasi, Antin-3, freeze thaw, uji mekanik
Formulasi dan Evaluasi Ekstrak Bawang Dayak (Eleutherine palmifolia L.Merr) dalam Sediaan Gel sebagai Anti Jerawat
Authors: Agustin Eriska , Yanti Nopri
Published: January 2024

The Dayak onion plant (Eleutherine palmifolia L.Merr) is a plant that has many health benefits. Empirically, this plant is used to treat acne on the skin caused by the bacteria Staphylococcus aureus. This study aims to formulate and evaluate Dayak onion extract in a gel preparation as an anti-acne at extract concentrations of 1%, 5% and 10%. The results showed that the preparation was brown in color, semi-solid homogeneous texture, typical aroma of Dayak onion, the average pH range of F1, F2, and F3 preparations was 5.2-5.34, the viscosity test range showed a value of 4140-9420 mPas, the range the spreadability test results were 4.07-4.46, and the irritation index for the F1 preparation was 0 (not irritating), while the F2 and F3 preparations were 0.3 (very mild irritation). Testing for anti-acne activity obtained an average inhibition zone of F1 0.3 ± 0.010 mm, F2 0.325 ± 0.014 mm, and F3 0.675 ± 0.021 mm where as the positive control used Medklin® 1%, the diameter of the inhibition zone was 1.75 ± 0.04 mm. The conclusion of this study is that the F3 preparations have the preparations that meet the physical evaluation requirements and the greatest bacterial inhibition value.
Keywords:          Acne, Dayak Union, Skin, Staphylococcus aureus
 
Abstrak
Tanaman bawang dayak (Eleutherine palmifolia L.Merr) merupakan salah satu tanaman yang memiliki banyak khasiat bagi kesehatan. Secara empiris, tanaman ini digunakan untuk mengobati jerawat pada kulit yang disebabkan salah satunya oleh bakteri Staphylococcus aureus. Penelitian ini bertujuan untuk memformulasikan dan mengevaluasi ekstrak bawang dayak dalam sediaan gel sebagai anti jerawat pada konsentrasi ekstrak 1%, 5%, dan 10%. Hasil penelitian menunjukkan sediaan berwarna coklat, tekstur semi padat yang homogen, aroma khas bawang dayak, rentang pH rata-rata sediaan F1, F2, dan F3 adalah 4,6-6,0, rentang uji viskositas menunjukkan nilai 4140-9420 cP, rentang hasil uji daya sebar 4,07-4,51, dan indeks iritasi sediaan F1, F2, dan F3 nilainya 0 (tidak mengiritasi). Pengujian aktivitas anti jerawat didapatkan rata-rata zona hambat F1 0,26 mm, F2 0,35 mm, dan F3 0,861 mm dimana kontrol positif menggunakan Medklin® 1% diameter zona hambatnya 1,83 mm. Kesimpulan dari penelitian ini adalah sediaan F3 memiliki sediaan yang memenuhi persyaratan evaluasi fisik dan nilai daya hambat bakteri yang paling besar.
Kata Kunci:         Bawang Dayak, Jerawat, Kulit, Staphylococcus aureus
Determinants of Intention and Attempt to Quit Smoking: A Study in Kalidawir Tulungagung
Authors: Yuliawati Riza , Yuliawati M. Ali , Indasah Indasah
Published: January 2024

Smoking cessation has been widely known as the right step to improve health. However, it has a low success rate. This research aims to identify demographic attributes (age, sex, income, and education), tobacco knowledge and spending and their impacts on smoking cessation intention and attempts in Kalidawir, Tulungagung Districts. A survey of 111 adult smokers is conducted using the GATS questionnaire. The data is analyzed using binary logistic regression. Most respondents, as many as 70 (63.1%), expressed a desire to quit smoking. Meanwhile, 41 respondents (36.9%) had no intention to quit smoking. Unfortunately, less than half, which is 43 (38.7%), had ever tried to quit smoking and more than half of the respondents, as many as 68 (61.3%), stated that they had never tried to quit smoking. Level of education and tobacco spending has a significant impact on intention to quit smoking (p-value 0,018 and p-value 0,024). While age, income, sex and knowledge do not affect the intention to quit smoking (p-value 0,954; p-value 0,145; p-value 0,975; and p-value 0,639). Education income and tobacco spending significantly impact the attempt to quit smoking (p-value 0,001; p-value 0,001 and p-value 0,008). While age, sex and knowledge do not affect the attempt to quit smoking (p-value 0,359; p-value 0,477; and p-value 0,993). Level of education and tobacco spending have significant impacts on intention and attempt to quit smoking while income only has an impact on smoking cessation attempts. The tobacco control program should consider these factors and make more comprehensive interventions.
Radrigán antes de Radrigán
Authors: Albornoz Farías Adolfo Enrique
Published: January 2024

En 1979, Juan Radrigán debutó como dramaturgo con Testimonio de las muertes de Sabina. En 1980 formó su propia compañía, el Teatro Popular El Telón. Recibió el Premio de la Crítica a la Mejor Obra en 1981 por Hechos consumados. Pronto devino el “dramaturgo revelación” del teatro chileno durante la dictadura y desde entonces ha sido reconocido como el “dramaturgo de los marginados”. Hasta ahora no han sido estudiadas la narrativa y la poesía que produjo antes de consagrase al teatro. A partir de una primera mirada a estos materiales, este artículo propone claves novedosas para revisitar la dramaturgia de Radrigán y, de paso, repensar el campo teatral chileno durante los años siguientes al golpe de Estado.
Tobacco Cultivation Regimentation: An Ethnographic Treatise from Pagergunung Village, Bulu, Temanggung
Authors: Nasution Pangeran Putra Perkasa Alam , Ahimsa-Putra Heddy Shri , Hudayana Bambang
Published: January 2024

Indonesia, as the sixth largest tobacco-producing country in the world, has participated in the Framework Convention on Tobacco Control (FCTC) by issuing compromise regulations through Government Regulation (PP) No. 109 of 2012. This regulation regulates restrictions on tobacco production and distribution of products made from tobacco raw materials. Furthermore, PP No. 109 of 2012 determines the increases in tobacco excise rates and the determination of limits on nicotine levels also sparked unrest among tobacco farmers in the Temanggung area. This article attempts to explain the insistence of farmers, especially in the eastern slope of Mount Sumbing, Pagergunung Village, Bulu District, Temanggung, in maintaining tobacco cultivation even though they are faced with an anti-tobacco campaign from the FCTC. The continued cultivation of tobacco can be understood as a form of regimen of cultivated plants. This article is an anthropological study with a regimentation theoretical perspective and ethnographic approach as a research method which presents the research results. From this research, it is known that the cultivation regimen is controlled by mythology, tobacco trade tricks, and the pretext of tradition as a socio-cultural surplus.
Mapping The Potential Creative Tourism Based Community to Build Creative Experience in Gianyar Regency
Authors: Wisudawati Ni Nyoman Sri , Sari Putu Ratna Juwita , Widhiasthini Ni Wayan
Published: January 2024

Gianyar regency has a diverse culture and crafts as one of authentic tourism attraction. This study aims to map the creative tourism potential in accordance with the distinction of the artisan village in Gianyar regency. This study solely examined the tourism potential of 14 creative village that had been identified by the government tourism office have creative potential to support promote Gianyar district as a World Craft City in 2023. In this study, a qualitative approach, checklist of observations was also made in each creative village along with interviews with informants from the Gianyar Regency Tourism Office and village head. Each village’s uniqueness and characteristics can be displayed by the development of creative ideas in packaging tourism potential as attractiveness and also other potential to support the main characteristic of the village to create branding of each village. Gianyar needs to market its tourist villages because the tourism potential of many of the villages is essentially comparable, so branding is necessary to each village to create their own identity and have competitiveness. Mapping of natural, cultural and arts made possibilities can be used to ascertain a village’s identity. Based on finding from 14 creative villages in Gianyar regency, it is possible to focus on expanding tourism potential in general while also creating creative tourism such as: Development of a Creative Tourism Village based on the crafts Industry, Development of Gastronomy-based Creative Tourism Villages, Development of a creative tourism village based on performing arts, Development of Nature-based Creative Tourism Villages.
Analisis Penetapan Pelayanan Pandu Tunda yang Berpengaruh pada Pendapatan Perusahaan (Studi Kasus PT Pelindo Regional 2 Sunda Kelapa)
Authors: Verawati Kencana , Wahyuni Ajeng Dwi Putri
Published: January 2024

Penetapan pelayanan pemanduan dan penundaan kapal merupakan pelayanan pertama dan terakhir yang diberikan kepada kapal yang akan masuk dan keluar dari suatu pelabuhan untuk memberikan pengarahan atas alur pelayaran setempat dan menuntun kapal yang akan berlabuh melalui wilayah yang tidak dipahami atau beresiko terhadap keamanan dan keselamatan pelayaran dalam menjaga muatan serta lingkungan maritim. Sampai dengan saat ini seluruh kapal di dermaga lokal yang ditangani PT Pelindo Regional 2 Sunda Kelapa belum menetapkan pelayanan pandu tunda, akan tetapi pada kondisi existing kapal-kapal besi yang masuk ke dermaga lokal pelabuhan sunda kelapa sudah terdapat kapal dengan ukuran di atas Gross Tonnage (GT) 500. Penetapan pelayanan ini diberikan atas keputusan Direktur Jenderal Perhubungan Laut. Pemilihan Skripsi ini bertujuan untuk menganalisis penetapan pelayanan pandu tunda yang berdampak pada pendapatan perusahaan yang berguna untuk gambaran PT Pelindo Regional 2 Sunda Kelapa dapat menetapkan pelayanan pemanduan dan penundaan kapal di dermaga lokal sehingga memperoleh tambahan pendapatan. Metode yang digunakan dalam penyusunan Skripsi ini adalah metode kuantitatif deskriptif dengan teknik pengumpulan data berdasarkan hasil observasi yang digunakan yaitu data kapal yang masuk ke pelabuhan sunda kelapa dan menggunakan rumusan perhitungan berdasarkan PM No.72 Tahun 2015 tentang Jenis, Struktur, Golongan dan Mekanisme Penetapan Tarif Jasa Kepelabuhanan. Hasil dari penelitian ini PT Pelindo Regional 2 Sunda Kelapa masih menunggu Keputusan Direktur Jenderal Perhubungan atas penetapan kelas perairan wajib pandu tunda dan pendapatan yang akan diperoleh perusahaan mencapai Rp. 626.087.843 dari 210 kapal yang sudah wajib mendapatkan pelayanan pemanduan dan penundaan dalam periode Janari-Maret 2022.
ESTALLIDO SOCIAL DE CHILE (2019-2020). CLAVES PARA ENSEÑAR LA TEMÁTICA DESDE UNA PERSPECTIVA CONTROVERSIAL EN LA FORMACIÓN DEL PROFESORADO
Authors: Sepúlveda Humberto Álvarez
Published: January 2024

En este artículo se desarrollan lineamientos didácticos que permitan al cuerpo académico formar a los futuros profesores de historia para que sean capaces de enseñar, en forma controversial, el estallido social de Chile a las nuevas generaciones de alumnos y alumnas. Para lograr este propósito, se describe el contexto histórico de auge y crisis de la revuelta popular ocurrida entre el 18 de octubre de 2019 y finales de 2020, se examina la integración de la historia reciente asociada al estallido social en el currículum chileno y, por último, se analizan los principales aspectos didácticos que se deben considerar al momento de incorporar la enseñanza del proceso histórico consignado en la formación del profesorado de historia. Metodológicamente, este trabajo es una investigación documental exploratoria basada en el análisis descriptivo-argumentativo de textos extraídos de las bases de datos de Redalyc, Clacso, Scopus, Wos, Scielo, ProQuest y Dialnet.
GAMERS E O BOLSONARISMO: ANÁLISE DOS ENUNCIADOS SOBRE JAIR BOLSONARO EM UM FÓRUM GAMER BRASILEIRO
Authors: Velho Eduardo , Henn Ronaldo
Published: January 2024

Outer Space é um fórum de internet e site de notícias brasileiro especializado no universo gamer, o qual faz parte de uma rede de sites e plataformas digitais que vem sendo chamada de machosfera. Frente ao crescente impacto que comunidades online exercem sobre questões políticas e acontecimentos contemporâneos, o tema deste trabalho é a análise dos enunciados sobre Jair Bolsonaro no fórum Outer Space. O objetivo é analisar a forma como os participantes do Outer Space defendem as ideias bolsonaristas. O problema de pesquisa é o seguinte: quais são os argumentos que os participantes do Outer Space utilizam para defender as ideias bolsonaristas? O método utilizado corresponde uma análise de conteúdo Qualitativa sob um corpus de 60 publicações extraídas do “tópico oficial sobre Jair Bolsonaro”. Os resultados sugerem que a maior parte dos participantes promovem enunciados de apoio a Jair Bolsonaro, na maior parte das vezes justificados por uma percepção de superioridade moral.
ARBITRABILNOST ISKLJUČENJA ČLANA DRUŠTVA S OGRANIČENOM ODGOVORNOŠĆU
Authors: Arambašić Jelena
Published: January 2024

The core of the work is a positive-legal analysis of the arbitrability of the exclusion of an LLC member. To justify the positive attitude towards the arbitrability of these proceedings, German jurisprudence and court practice were analysed, since they have been proven to be the most fruitful creators and shapers of the subject of arbitrability in company law and, as the most significant authority on this issue, have created over the years, a series of relevant works and decisions, primarily the trilogy (or tetralogy) of Schiedsfähigkeit/Arbitrability decisions. It has been argued that the possibility of excluding the jurisdiction of courts in proceedings for the exclusion of an LLC member and, instead, of forming an arbitration court is the result of private autonomy in limited liability companies, whose limitations are determined in advance. The paper holds an affirmative position regarding the arbitrability of the exclusion of an LLC member based on the LLC’s articles of organization and the exclusion due to an important reason, because of the objective and subjective arbitrability of the exclusion procedures.
MINDBOT: DESIGN AND IMPLEMENTATION OF A MIND-CONTROLLED EDUCATIONAL ROBOT TOY FOR DISABLED CHILDREN
Authors: Khalid Sibar J. , Ali Ismael A.
Published: January 2024

The mindBot robot is a new educational robot toy that can be controlled by brain signals and voice commands. It was evaluated with children with disabilities as well as healthy children as the potential users. The most significant challenge was the size of the used Emotiv Insight electroencephalogram headset when adjusting it on the children’s’ heads. Despite all the challenges, the mindBot robot is a promising technology that could be fun and educational for disabled children. The 11 participants took 36 minutes to finish all tasks on average. This includes the time they spent setting up the robot for the first time, putting on the headset, learning how to use the robot, and using the main educational features. The System Usability Scale usability score for the robot is 71.13, which is considered to be the score of good. The future stages of improving the mindBot includes adding more mobility capabilities and adding the feature of educational assessment.
An overview on important ethnomedicinal plants of Rajasthan with their antimicrobial properties
Authors: Soni Saloni , Pareek Aparna
Published: January 2024

In era of synthesized drugs, where individuals totally depend upon the chemical formulations of medication that may have adverse effects, people should re-establish their bond with nature. The gradual increase in multidrug resistance (MDR) and antimicrobial resistance (AMR) of pathogens is a great concern of worry to the world and obviously for this purpose, novel and effective bioactive constituents from the plants should be explored to get rid of this panic situation. Researchers are searching for the favourable natural source to fight with various antimicrobial diseases. Present study deals with the importance of precious herbs and plants from the treasure of nature and also listed some important ethnomedicinal plants with their bioactive ingredients from the region of Rajasthan.
β-galactosidase in prebiotic synthesis: A review
Authors: Sharma Kiran Bala , . Savitri
Published: January 2024

β-galactosidases (EC3.2.1.23) are among the most promising glycosidases with both hydrolytic and trans-glycosylation activities. β-galactosidases have historically been used to break down lactose in dairy products, helping those who are lactose intolerant. Attractively, under specific in vitro conditions, β-galactosidases show glycosyl transfer activity. They are able to synthesize carbohydrates easily, effectively and sustainably from inexpensive starting materials. Lactose, which is hydrolyzed by β-galactosidases, results in a variety of trans-galactosylation products called galacto-oligosaccharides (GOS) and fructo-oligosaccharides (FOS) which have been shown to have a number of health effects as prebiotics. Prebiotics are indigestible substances that have a major positive impact on the health of their hosts. Galacto-oligosaccharides (GOS) are structurally related to oligosaccharides found in human milk and have excellent prebiotic benefits. Scientists are seeking to industrially produce prebiotics because meals naturally contain small amounts of fructo- and galacto-oligosaccharides. This review emphasizes the value of β-galactosidases in prebiotic synthesis while concentrating on diverse sources of the enzyme.
The role of positive institutions in language teachers’ well-being
Authors: Majchrzak Ola , Osuch Aleksandra
Published: January 2024

Positive psychology was established on three fundamental principles: positive emotions, positive character traits that lead to a fulfilling life, and positive institutions that foster an environment for growth and prosperity. However, positive emotions and character traits have mostly been the focus of psychological research, while positive institutions, the organisations that support such growth, have received noticeably less attention. We tried to fill the gap by taking a closer look at a primary school in Lodz, Poland – SP 81, which calls itself a positive institution (Budząca się Szkoła). The purpose of the study is to ascertain whether SP 81, a positive institution, has an effect on language teachers’ well-being. Additionally, it was intended to determine whether a positive institution plays a significant role in the lives of language teachers and what that role is. The way school influences the teachers’ well-being is examined from three different perspectives: the physical aspect, the pedagogical approach and the psychological aspect, by means of one-to-one interview with each teacher. The results demonstrate that the institution and all three different perspectives have a significant impact on language teachers’ well-being. The study is hoped to have contributed to positive psychology research by demonstrating what it means to be a positive institution in practice.
Wolf-Hirschhorn syndrome: review of three clinical cases
Authors: Косинова Е.И. , Зубцова Т.И. , Полшведкина О.Б. , Колесникова Ю.Г.
Published: January 2024

Синдром Вольфа–Хиршхорна – один из редких, но узнаваемых наследственных синдромов, клинических случаев которого описано несколько десятков. В статье представлена информация о трех клинических наблюдениях за детьми с синдромом Вольфа-Хиршхорна. У двоих детей диагноз был подтвержден хромосомным микроматричным анализом высокого разрешения, у одного – стандартным цитогенетическим обследованием. В двух случаях хромосомный дисбаланс возник de novo. У двоих детей выявлена изолированная делеция 4р (р15.3 и 4р16.3), у одного – сочетание с микродупликацией 8р23.1-р23.3. У всех пациентов наблюдались общие фенотипические особенности: орбитальный гипертелоризм, диспластичные низко расположенные ушные раковины, короткий фильтр, малая верхняя губа. У всех детей отмечались выраженная мышечная гипотония с рождения, задержка психомоторного развития и судорожный синдром с необходимостью назначения и индивидуального подбора противосудорожной терапии. У всех детей диагностирована выраженная белково-энергетическая недостаточность, трудно корригируемая в связи с плохой переносимостью искусственных смесей. У одного пациента была выявлена энхондрома. Наш опыт, представленный в данной статье, позволяет дополнить данные о синдроме и расширяет когорту, описанных в литературе случаев.

Wolf–Hirshhorn syndrome is one of the rare but recognizable hereditary syndromes, of which several dozen clinical cases have been described. The article describes three clinical observations of children with Wolff-Hirschhorn syndrome. In two children, the diagnosis was confirmed by high-resolution chromosomal microarray analysis, in one by standard cytogenetic examination. In two cases, the chromosomal imbalance arose de novo. Two children had an isolated 4p deletion (p15.3 and 4p16.3), one had a combination with an 8p23.1-p23.3 microduplication. All patients had common phenotypic features: orbital hypertelorism, dysplastic low-lying auricles, short filter small upper lip. All children had pronounced muscular hypotonia from birth, psychomotor retardation and convulsive syndrome with the need for prescription and individual selection of anticonvulsant therapy. All children were diagnosed with severe protein-energy deficiency, which is difficult to correct due to poor tolerance of artificial mixtures. One patient was diagnosed with enchondroma. Our experience presented in this article allows us to supplement the data on the syndrome and expand the cohort of cases described in the literature.
The expression of fibrogenesis genes in tissues of patients with carotid atherosclerosis
Authors: Гончарова И.А. , Слепцов А.А. , Королева Ю.А. , Назаренко М.С.
Published: January 2024

У больных атеросклерозом сонных артерий проведен полногеномный сравнительный анализ экспрессии между клетками сонных артерий в области атеросклеротических бляшек (САБ, n=3) и интактными внутренними грудными артериями (ВГА, n=2) с использованием микрочипов HumanHT-12_V4 BeadChip (Illumina, США). Выполнена таргетная оценка экспрессии генов ADAMDEC1, ITGB5, TIMP2 и ММР3 в лейкоцитах крови пациентов с атеросклерозом сонных артерий (n=21). Выявлено что в САБ наблюдается существенное увеличение экспрессии генов внеклеточного матрикса (CD44, COL1A2, COL3A1, COL5A2, FMOD, HAPLN1, ITGA11, ITGAV, SPARC, SPP1, SULF1, TIMP1; |FC|≥2; pFDR=1,44×10-7). Гены ADAMDEC1, ITGB5 и TIMP2 характеризуются увеличением экспрессии в САБ по сравнению с ВГА (рFDR=0,018; рFDR=0,011; рFDR=0,006 соответственно). Гены ADAMDEC1, ITGB5 и TIMP2 экспрессируются в лейкоцитах периферической крови больных, где набольший уровень экспрессии показан для гена TIMP2. Оценка изменения уровня экспрессии в зависимости от генотипов показала, что у носителей генотипа ТТ rs1007856 гена ITGB5 наблюдается самый низкий уровень экспрессии гена по сравнению с носителями генотипов СС и СТ (p=0,034). Таким образом, атеросклероз сонных артерий связан с увеличением функциональной активности генов фиброгенеза в сосудах и лейкоцитах крови. Полиморфизм rs1007856 является eQTL для гена ITGB5 в лейкоцитах крови пациентов.

We performed a whole-genome comparative analysis of gene expression in tissues of patients with carotid artery atherosclerosis using HumanHT-12_V4 BeadChip (Illumina, USA) microarray. We compared the expression between cells of the carotid artery in the area of atherosclerotic plaques (CAP, n=3) and intact internal mammary arteries (IMA, n=2). The targeted expression assessment was performed for ADAMDEC1, ITGB5, TIMP2, and ММР3 genes in blood leukocytes of patients (n=21). A significant increase in expression of extracellular matrix organization genes (CD44, COL1A2, COL3A1, COL5A2, FMOD, HAPLN1, ITGA11, ITGAV, SPARC, SPP1, SULF1, TIMP1; |FC|≥2; pFDR=1,44×10-7) was detected in CAP. The ADAMDEC1, ITGB5, and TIMP2 genes, are characterized by increased expression in CAP, compared with IMA (рFDR=0.018; рFDR=0.011; рFDR=0.006, respectively). The ADAMDEC1, ITGB5, and TIMP2 genes are also expressed in peripheral blood leukocytes of patients; the highest level of expression is shown for the TIMP2 gene. Assessment of the expression level changes depending on genotypes showed that carriers of the TT genotype of rs1007856 in the ITGB5 gene have the lowest level of gene expression compared to carriers of the CC and CT genotypes (p=0.034). Thus, carotid atherosclerosis is associated with an increase in the functional activity of fibrogenesis genes in vessels and blood leukocytes. The rs1007856 polymorphism is an eQTL for the ITGB5 gene in patients’ blood leukocytes.