bluuebunny/crossref_metadata_2025 huggingface dataset:
Occurrence of tosudite in the Guezouman, Tarat and Tchirezrine 2 formations, hosts of uranium deposits in Niger (Tim Mersoï basin)
Authors: Billon Sophie , Patrier Patricia , Beaufort Daniel , Sardini Paul , Wattinne-Morice Aurélia
Published: October 2017

Tosudite, a regularly interstratified chlorite-smectite, crystallizes as an alteration mineral of several preexisting Al-bearing silicates (feldspars, kaolin minerals, chlorites) present in arkosic sandstones hosted in uranium deposits in Niger. X-ray diffraction patterns show a sharp superstructure at 29–29.6 Å for an air-dried state and a peak at 30.8–31.6 Å following ethylene glycol solvation. The 060 reflection at 1.507–1.509 Å indicates an overall dioctahedral character, and the very low coefficient of variation of the d00l reflections for the solvated mineral (0.03–0.13) permits validation of the regular interstratification justifying its identification as tosudite. Microprobe analysis allowed specification of the component layers of this mixed-layer mineral. The chlorite is a di-trioctahedral type analogous to sudoite (Si3Al4Mg2(OH)8), and the smectite component is a low-charge montmorillonite type Tosudite is characterized by large Al2O3 and MgO contents and small Fe content; its composition corresponds approximately to the formula where octahedral occupancy is ∼7. Scanning electron microscope (SEM) observations show that tosudite is closely associated with some uranium minerals: tosudite crystallization occurred during a late alteration event which post-dates burial diagenesis and during which uranium was remobilized by Mg-rich oxidizing fluids.
Dissolution of the chrysotile structure in nitric-acid solutions at different pH
Authors: Hongo Teruhisa
Published: October 2017

The nitric-acid dissolution of chrysotile was investigated with the aim of revealing the effect of pH on its structure. Chrysotile becomes more soluble at lower pH, with the octahedral, brucite sheet more readily dissolved than the tetrahedral sheet. The dissolution of the brucite sheet increases the pH of the solvent, because of the release of OH− groups along with the Mg2+ ions. At pH 2.00, the characteristic cylindrical fibre bundle structure of chrysotile is retained after dissolution, although the outside surface of each fibre becomes rough. Chrysotile remains fibrous upon dissolution at pH 1.08, but the fibres are no longer crystalline and their cylindrical structure collapses. The nitric-acid treatments result in an increase in both the specific surface area and the pore volume of chrysotile.
Palaeoclimatic implications of high-resolution clay mineral assemblages preceding and across the onset of the Palaeocene–Eocene Thermal Maximum, North Sea Basin
Authors: Kemp Simon J. , Ellis Michael A. , Mounteney Ian , Kender Sev
Published: October 2017

Understanding the composition of clay-rich sediments and their transportation into proximal marine basins allows us to better decipher hydroclimatic changes before and within the Palaeocene–Eocene Thermal Maximum (PETM). Only a limited number of such studies exists from the North Sea Basin, which was proximal to the volcanic activity and early rifting hypothesized to have triggered the PETM. The present study examines core material from well 22/10a-4, UK North Sea, as it exhibits an exceptionally expanded and almost stratigraphically complete fine-grained sedimentary sequence suitable for high-resolution analysis.

QuantitativeNewmod-for-Windows™-modelled clay mineral assemblages, rather than traditional semi-quantitative estimates, are dominated by smectite-rich, interlayered illite-smectite that probably developed from volcanogenic deposits on continental landmasses. Soil development before the PETM is consistent with the existence of a seasonal tropical climate with a prolonged dry season. A striking rise and fall of kaolinite content within the PETM onset, prior to the principal carbon-isotope excursion, is reported here. This variation is interpreted as a signal of an enhanced hydrologic cycle producing an increase in erosionally derived kaolinite, followed by a dampening of this detrital source as sea-levels rose. Global variations in PETM kaolinite concentrations are consistent with a latitudinal shift in patterns of precipitation in models of global warming.
Disorders of erythrocyte hydration
Authors: Gallagher Patrick G.
Published: October 2017

The erythrocyte contains a network of pathways that regulate salt and water content in the face of extracellular and intracellular osmotic perturbations. This allows the erythrocyte to maintain a narrow range of cell hemoglobin concentration, a process critical for normal red blood cell function and survival. Primary disorders that perturb volume homeostasis jeopardize the erythrocyte and may lead to its premature destruction. These disorders are marked by clinical, laboratory, and physiologic heterogeneity. Recent studies have revealed that these disorders are also marked by genetic heterogeneity. They have implicated roles for several proteins, PIEZO1, a mammalian mechanosensory protein; GLUT1, the glucose transporter; SLC4A1, the anion transporter; RhAG, the Rh-associated glycoprotein; KCNN4, the Gardos channel; and ABCB6, an adenosine triphosphate–binding cassette family member, in the maintenance of erythrocyte volume homeostasis. Secondary disorders of erythrocyte hydration include sickle cell disease, thalassemia, hemoglobin CC, and hereditary spherocytosis, where cellular dehydration may be a significant contributor to disease pathology and clinical complications. Understanding the pathways regulating erythrocyte water and solute content may reveal innovative strategies to maintain normal volume in disorders associated with primary or secondary cellular dehydration. These mechanisms will serve as a paradigm for other cells and may reveal new therapeutic targets for disease prevention and treatment beyond the erythrocyte.
Oncogenetic mutations combined with MRD improve outcome prediction in pediatric T-cell acute lymphoblastic leukemia
Authors: Petit Arnaud , Trinquand Amélie , Chevret Sylvie , Ballerini Paola , Cayuela Jean-Michel , Grardel Nathalie , Touzart Aurore , Brethon Benoit , Lapillonne Hélène , Schmitt Claudine , Thouvenin Sandrine , Michel Gerard , Preudhomme Claude , Soulier Jean , Landman-Parker Judith , Leverger Guy , Macintyre Elizabeth , Baruchel André , Asnafi Vahid
Published: October 2017

Key Points

In pediatric T-ALL, oncogenetic markers, MRD, and WBC count are independent predictors of outcome. These factors should be used together for individual treatment stratification.
Development of T-cell immunotherapy for hematopoietic stem cell transplantation recipients at risk of leukemia relapse
Authors: Dossa Robson G. , Cunningham Tanya , Sommermeyer Daniel , Medina-Rodriguez Indira , Biernacki Melinda A. , Foster Kimberly , Bleakley Marie
Published: October 2017

Publisher's Note: There is a Blood Commentary on this article in this issue.
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
Authors: Eriksson Mia , Peña-Martínez Pablo , Ramakrishnan Ramprasad , Chapellier Marion , Högberg Carl , Glowacki Gabriella , Orsmark-Pietras Christina , Velasco-Hernández Talía , Lazarević Vladimir Lj , Juliusson Gunnar , Cammenga Jörg , Mulloy James C. , Richter Johan , Fioretos Thoas , Ebert Benjamin L. , Järås Marcus
Published: October 2017

Key Points

TLR1 is upregulated on primitive AML cells. Agonistic targeting of TLR1/TLR2 induces apoptosis and differentiation of primitive AML cells in vivo.
Ossifications in Albright Hereditary Osteodystrophy: Role of Genotype, Inheritance, Sex, Age, Hormonal Status, and BMI
Authors: Salemi Parissa , Skalamera Olson Julie M , Dickson Lauren E , Germain-Lee Emily L
Published: October 2017

Context

Albright hereditary osteodystrophy (AHO) is caused by heterozygous inactivating mutations in GNAS. Depending on the parental origin of the mutated allele, patients develop either pseudohypoparathyroidism type 1A (PHP1A), with multihormone resistance and severe obesity, or pseudopseudohypoparathyroidism (PPHP), without hormonal abnormalities or marked obesity. Subcutaneous ossifications (SCOs) are a source of substantial morbidity in both PHP1A and PPHP.

Objective

This study investigated the previously undetermined prevalence of SCO formation in PHP1A vs PPHP as well as possible correlations with genotype, sex, age, hormonal resistance, and body mass index (BMI).

Design

This study evaluated patients with AHO for SCOs by physical examination performed by one consistent physician over 16 years.

Setting

Albright Clinic, Kennedy Krieger Institute; Institute for Clinical and Translational Research, Johns Hopkins Hospital; Albright Center, Connecticut Children’s Medical Center.

Patients

We evaluated 67 patients with AHO (49 with PHP1A, 18 with PPHP) with documented mutations in GNAS.

Main Outcome Measures

Relationships of SCOs to genotype, sex, age, hormonal resistance, and BMI.

Results

Forty-seven of 67 participants (70.1%) had SCOs. Patients with PHP1A and PPHP had similar prevalences and degrees of ossification formation. Patients with frameshift and nonsense mutations had much more extensive SCOs than those with missense mutations. Males were affected more than females. There was no correlation with hormonal status or BMI.

Conclusions

There is a similar prevalence of SCOs in PHP1A and PPHP, and the extent of SCO formation correlates with the severity of the mutation. Males are affected more extensively than females, and the SCOs tend to worsen with age.
Postoperative Outcomes in Obstructive Sleep Apnea Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis of Comparative Studies
Authors: Nagappa Mahesh , Ho George , Patra Jayadeep , Wong Jean , Singh Mandeep , Kaw Roop , Cheng Davy , Chung Frances
Published: October 2017

BACKGROUND:

Obstructive sleep apnea (OSA) is a common comorbidity in patients undergoing cardiac surgery and may predispose patients to postoperative complications. The purpose of this meta-analysis is to determine the evidence of postoperative complications associated with OSA patients undergoing cardiac surgery.

METHODS:

A literature search of Cochrane Database of Systematic Reviews, Medline, Medline In-process, Web of Science, Scopus, EMBASE, Cochrane Central Register of Controlled Trials, and CINAHL until October 2016 was performed. The search was constrained to studies in adult cardiac surgical patients with diagnosed or suspected OSA. All included studies must report at least 1 postoperative complication. The primary outcome is major adverse cardiac or cerebrovascular events (MACCEs) up to 30 days after surgery, which includes death from all-cause mortality, myocardial infarction, myocardial injury, nonfatal cardiac arrest, revascularization process, pulmonary embolism, deep venous thrombosis, newly documented postoperative atrial fibrillation (POAF), stroke, and congestive heart failure. Secondary outcome is newly documented POAF. The other exploratory outcomes include the following: (1) postoperative tracheal intubation and mechanical ventilation; (2) infection and/or sepsis; (3) unplanned intensive care unit (ICU) admission; and (4) duration of stay in hospital and ICU. Meta-analysis and meta- regression were conducted using Cochrane Review Manager 5.3 (Cochrane, London, UK) and OpenBUGS v3.0, respectively.

RESULTS:

Eleven comparative studies were included (n = 1801 patients; OSA versus non-OSA: 688 vs 1113, respectively). MACCEs were 33.3% higher odds in OSA versus non-OSA patients (OSA versus non-OSA: 31% vs 10.6%; odds ratio [OR], 2.4; 95% confidence interval [CI], 1.38–4.2; P = .002). The odds of newly documented POAF (OSA versus non-OSA: 31% vs 21%; OR, 1.94; 95% CI, 1.13–3.33; P = .02) was higher in OSA compared to non-OSA. Even though the postoperative tracheal intubation and mechanical ventilation (OSA versus non-OSA: 13% vs 5.4%; OR, 2.67; 95% CI, 1.03–6.89; P = .04) were significantly higher in OSA patients, the length of ICU stay and hospital stay were not significantly prolonged in patients with OSA compared to non-OSA. The majority of OSA patients were not treated with continuous positive airway pressure therapy. Meta-regression and sensitivity analysis of the subgroups did not impact the OR of postoperative complications for OSA versus non-OSA groups.

CONCLUSIONS:

Our meta-analysis demonstrates that after cardiac surgery, MACCEs and newly documented POAF were 33.3% and 18.1% higher odds in OSA versus non-OSA patients, respectively.
“Better, as in the Geneva”: The Role of the Geneva Bible in Drafting the King James Version
Authors: Miller Jeffrey Alan
Published: October 2017

The part played by the Geneva Bible in the composition of the King James Version (1611) has been a vexed issue from the very commissioning of the King James translation in 1604. This essay sheds new light on the issue by focusing in detail on two extant drafts of the King James translation, one that has only recently come to light. Both drafts not only reflect the translators' frequent recourse to the Geneva Bible but also show them taking care explicitly to signal this recourse in a distinctive, even surprising fashion. Detailed consideration of this crucial feature of the drafts illuminates the vital role played by the Geneva Bible in the King James Version's composition process, providing a better understanding of that process as a whole and of its fragmentary remains that survive today.
“To Write of Him and Pardon Crave”: Negotiating Biblical Authority in Lanyer's Salve Deus Rex Judaeorum
Authors: Fleck Andrew
Published: October 2017

Aemilia Lanyer refers extensively to the Gospels in writing her poem on the Passion, Salve Deus Rex Judaeorum. Alluding to the events of Christ's final day, she incorporates details from each of the Gospel accounts of the Crucifixion. Focusing on specific echoes of the translations available to her, it is possible to trace which bible Lanyer preferred. Surprisingly, despite Lanyer's preference for the Geneva translation, she also made use of the Bishops' Bible, suggesting that the poet carefully sifted through different English translations as she sought to generate biblical authority for her account of the Passion.
John Bois's Annotated Septuagint and the King James Bible
Authors: Hardy Nicholas
Published: October 2017

This article uses an annotated copy of the 1587 edition of the Septuagint, the ancient Greek translation of the Old Testament, as a window onto the relationship between biblical criticism and vernacular translation in early seventeenth-century England. The author recently identified the book's annotator as John Bois (1561–1644), one of the principal translators of the King James Bible of 1611. The article explains why this and other material pertaining to Bois and the King James Version has previously been overlooked and considers how further evidence might be uncovered in the future. As Bois's annotations indicate, translators' decisions were shaped by questions that scholars throughout post-Reformation Europe were asking about the Bible's cultural context, composition, and transmission. These technical questions all had important theological implications, which scholars of biblical translation will only be able to appreciate if they expand their horizons beyond national boundaries and look at Latin sources alongside vernacular ones.
Analysis of Normative Legal Acts in the Sphere of Development of the Arctic Zone of the Russian Federation in Order to Provide the Economic Stability of the Macroregion
Authors: Беляевская-Плотник Л. , Belyaevskaya-Plotnik L.
Published: October 2017

The article is devoted to the analysis of the normative and legal legislation designed to regulate the development of the Arctic zone of the Russian Federation in the aspect of ensuring the economic security of this macroregion. The analysis of the main federal and regional regulations has been carried out, Arctic preferences for business and the population have been singled out and systemized in the context of individual subjects and municipal entities, which are inherently a strong basis for ensuring the economic security of the macroregion. The analysis of legislative acts regulating the development of the Arctic zone and the legal relations between its subjects showed that today there are more than 500 regulatory legal acts in force, which, however, do not form a reliable legislative basis for the sustainable development of the Arctic territories. Today, there is a need for a single normative legal act with a full list of additional preferences in relation to legal entities that carry out economic activities in the Arctic (tax breaks, certain forms of state support, etc.), as well as to individuals who live and work in the territory (benefits for residents of the Far North, as well as for the small indigenous peoples of the North).
Construction of Modified Evaluation Models Financial Condition of Organizations
Authors: Аверина Татьяна , Averina Tatyana , Дорохин Ю. , Dorohin Yu. , Иванова О. , Ivanova O.
Published: October 2017

The article presents the results of calculations of the system of financial and economic indicators of the enterprises of machine building and food industry of the Central Federal District of the Russian Federation. The estimation of the probability of bankruptcy of enterprises according to Saifulin-Kadykov’s models and the Irkutsk State Economic Academy made it possible to reveal distortion of results for “problem” enterprises. On the basis of the analysis, the assumption was made that the models considered could be improved by replacing the return on equity ratio with the ratio of retained earnings to the value of the balance sheet total. Approbation of the modified models showed their high predictive characteristics.
IDEAS ABOUT NATIONAL IDENTITY IN RUSSIAN LITERARY REVIEW, HISTORICAL AND LITERARY DISCOURSES OF THE 19TH â€“ EARLY 20TH CENTURY
Authors: Krylov Viacheslav
Published: October 2017

This article analyses the evolution of literary reflections among the representatives of the 19th-early 20th-century trends and schools where ideas on national literature distinctness were formed. The study specifies both an invariant of the notions of national literature identity and individual variations that did not find further development in literary self-awareness. The essays of the 1870-80s suggest that there was formed an image of the original literature opposed to European literature. A new impetus to the problem of national identity in literature was attached to the era of the Silver Age; however, the analysis of the literary review, historical and literary discourses of the turn of the century leads to the conclusion that it was in this era that the ideology of literary centrism was further strengthened, and the exclusive status of Russian literature in culture received detailed reflection.
TRANSLATION AND DICTIONARIES IN FOREIGN LANGUAGE ACQUISITION: THE CASE OF THE LATVIAN LANGUAGE
Authors: Laiveniece DiÄna , Lauze Linda
Published: October 2017

In modern linguodidactics, there is no uniform understanding of the necessity of translation in the acquisition of a foreign language. The aim of the research is to find out the language attitudes held by full-time and Erasmus exchange program foreign students towards translation in acquiring Latvian as a foreign language on language proficiency level A1 and A2.The research is based on a qualitative study dealing with the results of survey data as well as direct observations inferred from the work with foreign students. The questionnaire consists of 11 questions on translation and usage of dictionaries and a question about personal information. The answers of 35 respondents from 12 countries have been analyzed. 91.43 % of the respondents enjoy translation tasks, only 8.57 % of answers are negative. The highest evaluation was given for word translation, that is, 4.23 for translation from a foreign language (Latvian) into English (being the intermediary language) and 4.15 the other way round in a five point scale. Diverse linguistic experience, differences among language systems, studentsâ€™ language attitudes establish the purposeful use of translation in foreign language acquisition.
OVERVIEW OF LEGAL FRAMEWORK OF PUBLIC PRIVATE PARTNERSHIPS IN ALBANIA
Authors: Lleshi Ermira
Published: October 2017

Albania has made positive steps in improving the legal framework of Public Private Partnerships (PPPs) and the political environment. The laws have encountered several amendments in the last 10 years, but there is still room for improvement. Albania has incorporated the EU directives and the UNCITRAL recommendations into PPPs legislation and we have to admit the effectiveness of the law 125/2013 â€śOn concessions and public private partnership.â€ť This paper aims to present a view of the actual legal and sublegal framework of PPPs in our country and to note the development of this sector in potential benefits for both sectors, private and public.Moreover, judicial quality has improved in Albania even though there is room for further improvement. Moreover, there has been noticed a strengthening of institutional capacity due to co-ordination of consultants and external advisers, but government agencies are at the early stages of developing PPPs. The political environment for PPPs is favourable, especially in the energy and transport sector. Further improvement is required in the transparency and fairness of procedures in practice.
DESIGN, ANALYSIS AND IMPLEMENTATION OF ELECTRONIC TEST FOR KNOWLEDGE EVALUATION IN THE COURSE OF INFORMATION TECHNOLOGIES FOR PHARMACEUTICAL STUDENTS
Authors: Manev Hristo , Manev Mancho
Published: October 2017

The increased usage of information technologies in everyday life and especially in education leads to demands for new forms of teaching, studying and the appropriate examination and evaluation of acquired knowledge and skills of the students.Modern electronic educational systems use only those technologies that improve the learning process and make it more effective. Interactive education provides an opportunity to develop skills for independent literature research and activation of cognitive activity.In this work, it is shown how modern electronic education is implemented in the curriculum of English language pharmaceutical students at the Medical University â€“ Plovdiv in the course of Information Technologies. It is developed with a methodological approach of a hybrid system, i.e. compulsory attendance at lectures in combination with two different types of conduction of the final test for comparison â€“ a paper-based test and a remote web-based one. The results received from the parallel tests are processed and analyzed and the conclusions are used to enhance the quality of the developed test and the type of implementation. Moreover, the examined students fill in an anonymous poll to show the authors their thoughts for this type of hybrid educational system.
A COMPARISON BETWEEN UNDERGRADUATE POLYTECHNIC AND MEDICAL EDUCATION SYSTEMS IN ROMANIA
Authors: Dehelean Liana , Romosan Ana Maria , Papazian Petru , Babaita Mircea
Published: October 2017

Background: While medical and polytechnic education systems seem dissimilar in approach, they both share a certain level of difficulty. After graduating, polytechnic students find easy employment in national or multinational companies, whereas medical students are presented with more job opportunities abroad. The purpose of the study was to compare studentsâ€™ satisfaction with training and career preferences from a technical and a medical perspective. The methods were as follows: the study participants were divided in two samples (polytechnic and medical undergraduates) and asked to fill in a satisfaction questionnaire regarding their professional training. In addition, they were invited to express options about the intended future career. Results: we found no differences between the two samples regarding the participantsâ€™ satisfaction with teaching staff and labs. Polytechnic students have more Ph.D. opportunities while medical students were more involved with participation in conferences. Satisfaction with lectures and practical projects was significantly higher among medical students. Conclusions: Both polytechnic and medical students rate their training as satisfying, and half of them consider leaving the country.
DOES EMOTIONAL MATURITY HELP TO EXPRESS MORAL BELIEFS? EVALUATING â€MORAL GAMES FOR TEACHING BIOETHICSâ€™ AMONGST ROMANIAN AND POLISH STUDENTS
Authors: PĹ‚otka Bartosz , Ghenu Cristina Iulia , Brad Laura
Published: October 2017

The recent development of biotechnology generated a new set of individual and public moral dilemmas gathered under the name of bioethics or biopolitics. These issues are specific because they merge â€“ as nothing else before â€“ moral, private and political spheres. Thus, public awareness of these cases and of any elements that can influence personal bioethical decisions must be stimulated. One of such methods is the academic teaching of bioethics. Since Darryl R.J. Macer defined the latter as â€śthe love of life, reflecting the hope that bioethics may value life in a process involving emotions and rationalityâ€ť we found interesting to investigate the role of emotional maturity (EM) in solving bioethical dilemmas. The study involved 103 Polish and Romanian students asked first to fill the Friedmanâ€™s emotional maturity form and then solve chosen exercises based on UNESCOâ€™s Moral Games for Teaching Bioethics. The results indicate that a high level of emotional maturity correlates positively with the studentsâ€™ ability to express their moral beliefs for Romanians and negatively for Poles; therefore, the results indicate there is a need to modernize the actual standards for teaching bioethics by enriching them with either emotional or rational components according to the cultural premises.
THE HUMAN FACTOR IN RESEARCH PROJECTS CONDUCTED AT POLISH UNIVERSITIES
Authors: PtaszyĹ„ska Ewa
Published: October 2017

This article is based on research conducted at the Wroclaw University of Science and Technology and was financed by the National Centre of Science with the purpose of identifying success and failure factors for university research projects. The research shows that the human factor was crucial in determining the outcome of university research projects. This article presents the analysis and results of selected aspects of a research project into human resource management. The study involves in-depth interviews with 40 project managers of university research projects. Based on interview responses, the following features are evaluated: main reasons for starting research projects, different methods of selecting the research project manager, research team member selection criteria, management styles used by research projects managers, and crucial problems connected with the human factor that occurred in the research projects being analyzed.
METHODS OF ATTRACTION AND RETENTION OF GENERATION Z STAFF
Authors: Sidorcuka Irina , Chesnovicka Anna
Published: October 2017

The contemporary job market is facing the arrival of new type of employee â€“generation Z representatives, known as â€śdigital nativesâ€ť, who are described as technological, social, global and developed, the most connected, clever and educated generation thatever existed before, driven by social media, influenced by brands and musical culture. At the moment, this generation is considered to be two billion big.This study is looking at the existing methods of generation Z staff attraction and retention in the company Evolution (Latvia), where they make a majority. Further analyzing which of the methods are perceived as most efficient and which values of this generation are met by the company. Methods include company literature review, questionnaires and interviews. It was concluded the Gen Z have specific preferences in communication and can be reached through a variety of social platforms and special events provided by the company. As potential and current employees, they are not looking for life-long employment, put forward their specific values and expect the potential employer to attract them by meeting their needs in terms of flexible working hours, flexible (varied) jobs where their individuality can be applied, company excellent reputation, innovation, speed of change, platform for educational and promotional advancement, specific fringe benefits.
ACCOUNTANTâ€™S PROFILE: PERCEPTION OF STUDENTS AND PRACTITIONERS
Authors: Subaciene Rasa , Senkus Kastytis
Published: October 2017

The profession of the accountant has many aspects. Accountants shape the largest amount of information in an enterprise and play an important role in the enterprise's activity. This profession is highly regulated, very responsible and usually includes a wide range of topics: including but not limited to different spheres of accounting, formation of accounting policies, or even information system for enterprises. This suggests the need for an investigation into the accountant's profile, in order to determine the set of features which ideally should be developed for the profession. The purpose of the article is to investigate the accountant's profile from the perception of students and practitioners. For the achievement of this purpose the following methods were used: a questionnaire-based study, information systematization, comparison, and summarization. The results of the research from the study were used for the evaluation of the profile of the accountant, for the development of the necessary set of features an accountant should hold, and finally, the results may be used for the future assessment of accounting study programs of higher educational institutions.
RESEARCH ON THE MANAGEMENT SKILLS AND ABILITIES ACQUIRED IN THE MILITARY EDUCATION SYSTEM
Authors: Terziev Venelin , Nichev Nikolay
Published: October 2017

The socio-economical changes in the Bulgarian society leave their traces in all spheres of public life and in the military education system in particular. The implemented reforms in the Republic of Bulgaria assign to military higher schools the task to train officers with management skills and abilities at a higher level, ready to solve efficiently complicated and versatile tasks. The specific character of the non-combatant officerâ€™s activity, sets increased requirements to their training and assurance of its effectiveness. The non-combatant cadetâ€™s management skills and abilities appear to be significant indicators of improving the effectiveness in the military professional training for management activity and developing a readiness for the timely taking of quality management decisions. The research target is the professional military training of the future logistic officers. The research aim is to analyze the acquired skills and abilities in the course of professional military training management and to related to them management effectiveness. The methods of research are: theoretical analyses of the military education literature, inquiry, statistics, substantiation and general conclusions.
PUBLIC FUNDING OF ICT IN BULGARIAN SCHOOL EDUCATION (2012-2015)
Authors: Varbanova Teodora
Published: October 2017

This article aims to present state policy in respect of the provision of ICT in schools and more specifically â€“ computerized workplaces. The definition of the author for computerized workplaces: desktop, laptop, terminal or (hybrid) tablet. For this purpose, the presented and analyzed data are from the implementation of the Ministry of Education and Science in Bulgaria National Program "Information and communication technologies (ICT) in the schools" for the period: school years 2012/2013, 2013/2014 and 2014/2015. The data are obtained from the Ministry of education and science in February 2015 in response to a request for access to public information by the author. In this article some of the analyzed data give objective information about the state funding for securing computerized workplaces and the total amount of investments, and effectively covered schools, for the survey period.
MOTIVATING FACTORS FOR SCIENCE COMMUNICATION IN LATVIA
Authors: VÄ«Ä·e JustÄ«ne
Published: October 2017

There is a public demand for communication of scientific findings that account for fragmentary expression of activities included in different science communication models. This study identifies factors facilitating the involvement of the scientific community in science communication. The primary data were obtained by a qualitative method of in-depth, semi-structured, expert interviews involving ten representatives of the Latvian scientific community relating to exact sciences, life sciences, and humanities and social sciences. The study distinguishes two categories for engaging the scientific community in science communication: a formally recognized approach and one involving a third party for organizing the communication.
ROMANIAN HUMANISM IN THE PHILOSOPHICAL VISION OF CONSTANTIN MICU STAVILA
Authors: Zaharia Frăguța
Published: October 2017

The present European context challenges us to approach the issues of Romanian dignity, humanity and humanism. The purpose of this essay is to emphasize the interpretative and explanatory dimensions of Constantin Micu Stavila’s philosophical thinking focused on the meaning of life and the human destiny, no less on the significance of the Christian personalism that the Romanian-French philosopher has cultivated it. Some questions arise: What is the role of philosophy and religion in understanding the meaning of life? How do we have to consider the human being and by especially the characteristics defining the Human within the Romanian culture? Trying to provide an honest, coherent and enlightening response, the paper is organized into two parts: 1. The mission of Romanian philosophy – attempting to demonstrate that the Romanian culture is integrating itself in the world-wide one seeing that there is an intimate complementarity of philosophy and religion; and 2. Romanian cultural messianism – developing an interpretation of the Romanian folklore according to the topic of the paper.
EMOTIONALLY EVALUATING THE ATTITUDE OF CONSUMERS TOWARD SUPERVISION SERVICE
Authors: Zakrizevska Maija
Published: October 2017

This study is conducted because organization supervision in Latvia tends to rapidly take its proper place among other professions recognized on the national level and has become an inseparable part of professional activities, in particular in the areas focused on humans, for example: health care, art therapies, social and educational services, and the business environment. Given that the demand for supervisors continues to increase, the purpose of this study is the identification of the popularity and treatment of supervision service by consumers for the subsequent presentation of proposals to the administration of the Business Art and Technologies University RISEBA concerning the popularization of supervision services and improvement towards the Master Program â€śManagement Psychology and Supervisionâ€ť. 111 respondents participated in the study, including respondents who have participated in supervision (n=47) and respondents who have never participated in supervision (n=64). The study has led to the conclusion that the attitude of consumers toward supervision is generally positive. Most of the respondents have never been parties to supervision, yet a majority of the respondents would like to experience it. There are statistically significant differences between the attitudes toward supervision in the cognitive dimension.
THE EFFECTS OF AN INNOVATIVE TECHNOLOGY APPLIED AS VIRTUAL REHABILITATION ON CLINICAL OUTCOMES IN ANTERIOR CRUCIATE LIGAMENT INJURY
Authors: AydoÄźdu Onur , SarÄ± ZĂĽbeyir , Yurdalan Ufuk Saadet , Polat GĂĽlden Mine
Published: October 2017

In recent years, many different technologies on virtual rehabilitation have been produced and used in research. However, existing studies are limited because most of them focus on the balancing ability of the elderly or studied stroke patients with same systems. Thus, it is necessary to investigate the effects of a new virtual rehabilitation system in patients with Anterior Cruciate Ligament (ACL) Reconstruction. The purpose of this study was to investigate the effects of a virtual rehabilitation system using a MarVAJEDÂ® system which provides visual and auditory stimulus aimed at educating and controlling the joint proprioception, range of motion, pain intensity, and knee swelling in individuals with an ACL injury. A total of fifteen patients with ACL reconstruction participated in this study. In addition to conventional physiotherapy, a virtual rehabilitation treatment was applied with visual and auditory stimulus for a total of eight weeks, three sessions per week. There were statistically significant improvements in measures of proprioception, range of motion, pain intensity, and knee swelling between preâ€“ and post â€“ treatment (p<0.05). We concluded that this new VR system known as MarVAJED effectively treat ACL patients by improving proprioception, range of motion, and by decreasing pain intensity, and knee swelling.
MICROCIRCULATORY DISORDERS IN WOMEN WITH POLYCYSTIC OVARY SYNDROME
Authors: Koleva Daniela , Batzelova Mariana , Nikolova Julia , Orbetzova Maria
Published: October 2017

: It is believed that microvascular dysfunction plays a major role in the development of insulin resistance (IR). Performing nailfold capillaroscopy witÂ­h evaluation of microvascular parameters in women with polycystic ovary syndrome (PCOS) would undoubtedly be helpful for the investigation of novel pathophysiological mechanisms in IR occurrence. The aim of the present study was to compare the values of microvascular parameters between PCOS patients and clinically healthy women and to assess its relationship with clinical and metabolic parameters in the PCOS women. Our study included 21 PCOS patients and 22 clinically healthy women (controls). Nailfold capillaroscopy was conducted and the following parameters were assessed: arterial limb diameter (d art), venous limb diameter (d ven), top diameter of loops (top d), length of loops, d art/d ven ratio, d ven/d art ratio, number of capillary loops (n cap), number of abnormal loops (% abn cap) and a presence of perivascular diapedesis. Weight, height, fasting plasma glucose (FPG), immunoreactive insulin (IRI), lipid parameters, total testosterone, systolic (SBP) and diastolic blood pressure (DBP) were measured in the PCOS women. Body mass index (BMI) and homeostasis model of insulin resistance index (HOMA-IR) were calculated. We found significantly higher values of age, BMI and % abn cap in the women with PCOS as compared to the controls. Interestingly, % abn cap showed a negative correlation with age. Furthermore, an inverse association between top d and the values of SBP and DBP was established. We determined a positive correlation between the presence of perivascular diapedesis and the values of FPG, HOMA-IR and testosterone. As a conclusion, the higher % abn cap in the PCOS women might be an early pathophysiological sign of microvascular dysfunction. The positive correlation between perivascular diapedesis and the degree of IR, hyperglycemia, and hyperandrogenemia shows the existence of a chronic low-grade inflammatory process in PCOS.
THE ROLE OF CIRCADIAN RHYTHMS AMONG MEDICAL STUDENTS IN TIME MANAGEMENT ORGANIZATION AND ACADEMIC ACHIEVEMENT
Authors: Modna Yuliya , Scott Bernadette
Published: October 2017

Time management is one of the biggest problems of medical students. In this study, we examined the circadian rhythms of medical students and factors which may affect academic performance: perceived stress, sleep quality, time management. Students answered a Morningness-Eveningness questionnaire, the Time Management Personal Assessment questionnaire, the Pittsburgh Sleep Quality Index (PSQI), and the Perceived Stress Scale questionnaire. The correlation (R=0.87) between chronotype and GPA (P<0.001) showed a higher GPA in students with morning chronotypes. The PSQI analysis demonstrated 47% of the students had poor sleep quality; a correlation (R= - 0.56) between the PSQI and GPA (p< 0.04), supporting a link between higher GPA and good sleep. Results also showed a correlation (R=0.59) between time management and GPA (p< 0.01), implying that the students with excellent time management skills (17%) had excellent GPAs. Chronotypes, quality of sleep and time management, influence GPA and can be used as a guidance tool for academic advisors.
CERVICAL BRUCELLOSIS, WITH OR WITHOUT BONE INJURY
Authors: RamosaĂ§o Ergys , Kolovani Entela , Rroji Arben , Kraja Dhimiter
Published: October 2017

Brucellosis is a zoonotic infectious systemic, endemic in Albania, which is accompanied by multi-organ involvement. A common complication is also the vertebral affection. Manifestation in the lower lumbar spine is frequently seen, while cervical involvement is more rare. Diagnose of vertebral involvement is difficult because of non-specific clinical symptoms. We present two cases of cervical brucellosis, with various cervical injuries. Spondylodiscitis with epidural abscess were the cervical manifestation in the first patient, which is very rare and a serious complication and the second patient had epidural involvement without spondylodiscitis. The Rose Bengal, Wright test, ELISA were positive for both patients. The cervical injury was confirmed with MRI exams. After prolonged combination therapy with cervical immobilization, the follow up evaluation demonstrated resolution of the cervical injury. Because vertebral destruction is in the base of this complication, early diagnosis of vertebral brucellosis is important to prevent serious morbidity, if diagnosis and treatment are delayed. Standard Brucella tube agglutination (Wright) test is the primary test and should be performed as a first step in the differential diagnosis of spondylodiscitis. An MRI is recommended for early diagnosis of spinal involvement. Medically treatment of cervical brucellosis has a good prognosis with early diagnosis.
THE IMPACT OF PHARMACEUTICAL CARE ON IMPROVING THE QUALITY OF LIFE IN PATIENTS WITH ALLERGIC RHINITIS
Authors: Todorova Anna , Tsvetkova Antoaneta , Mihaylova Silvia , Andreevska Kalina , Kondova Antonia , Arnaoudova Mariana
Published: October 2017

Introduction: Allergic rhinitis (AR) is a chronic disease with great social and economic impact that is largely undiagnosed and inadequately self-treated. Healthcare professionals such as pharmacists play a key role in recognizing and assessing the severity of AR, dispensing of OTC drugs, counseling of patients and in severe cases, referring them to health care specialists for further treatment.Objective: This study explores the impact of pharmaceutical care and patient counseling on the self-management of seasonal AR. Methods: The participating pharmacists follow the stepwise algorithm of ARIA (Allergic Rhinitis and its Impact on Asthma) Pharmacistâ€™s Guide. The effectiveness of the specialized pharmaceutical care is assessed by the changes in patientsâ€™ quality of life (QOL) before and after the provision of patient counseling and pharmacist monitoring on patient self-management. The quality of life is measured with the help of the generic tool 12v2 SF.Results: As a result of the provided pharmaceutical care, the analysis indicates improvement of all assessed aspects of patientsâ€™ QOL. The analysis shows that the better scores of the indicators Physical functioning, Vitality, Physical health and Mental health are not accidental; rather, they are in a statistically significant correlation with the provided pharmaceutical care.Conclusion: The study highlights the need for professional patient counseling and the education of patients to perform adequate disease management and improve their quality of life.
TRANSFORMING CONCUR TASK TREES MODEL INTO AN ABSTRACT USER INTERFACE
Authors: Atanasova Margarita , Malinova Anna
Published: October 2017

Business applications are difficult to use for the average user. An adaptive user interface improves employeesâ€™ productivity and is presented as a solution to this problem. However, developing user interfaces that are adapted to the needs and culture of the enterprise is time-consuming and expensive. We developed a software prototype for generating adaptive user interfaces that makes this process less time-consuming and more efficient. We propose an extension to the Cameleon Reference Framework project by Information Society Technologies, on the implementation level by adding an additional step for defining the Area of Business Operations. That way the prototype can extract business tasks for the selected industry therefore, presenting to the developer a more intelligent selection of predefined tasks. In this article, we also present a programming approach for transforming a task model, as defined by the ConcurTaskTrees notation, into an abstract user interface.
INVESTIGATION OF INDIGO DYEING USING SODIUM BOROHYDRIDE AS REDUCING AGENT
Authors: Buyukakinci Banu YeĹźim , Sokmen Nihal
Published: October 2017

Indigo, one of the oldest dyes, has a very important role for the textile sector. It is primarily used to dye cotton clothes, and blue jeans and over one billion pairs of jeans around the world are dyed blue with indigo. Although Sodium Hydrosulfite (Na2S2O4) is used as a reducing agent in most indigo dyeing processes, it is environmentally unfavorable because of the resultant contaminated toxic wastewater. In addition, the color fastnesses of dyed samples using Na2S2O4 as reducing agent are not good enough.In the present paper sodium borohydride (NaBH4) were used as ecologically safe reduction systems for the indigo dyeing of cotton fabric. After dyeing processes, the color yield and fastnesses according to washing and rubbing were measured, and results were compared.It was found when NaBH4 was used as reducing agent instead of Na2S2O4, the color yield and the fastness properties of the dyed samples improved.
STAPHYLOCOCCUS AUREUS FROM READY-TO-EAT FOOD AS A SOURCE OF MULTIPLE ANTIBIOTIC RESISTANCE GENES
Authors: ChajÄ™cka-Wierzchowska Wioleta , Zadernowska Anna , Ĺaniewska-Trokenheim Ĺucja
Published: October 2017

The emergence of antibiotic-resistant strains of S. aureus such as methicillin-resistant S. aureus (MRSA) is a worldwide problem. Ready-to-eat (RTE) food which does not need thermal processing before consumption could be a vehicle for the spread of antibiotic-resistant microorganisms. The present study evaluated the molecular genetic characteristics (RAPD) and pheno- and genotypical antimicrobial resistance profile of S. aureus isolated from 75 RTE food samples (sushi, hamburgers, salads). All of the isolates (n=32) were resistant to at least one class of antibiotic tested of which 75% strains were classified as multidrug resistant. Most of the isolates were resistant to cefoxitin (87,5%) followed by clindamycin (78,1%), tigecycline and quinupristin/dalfopristin (53,1%). All methicillin resistant staphylococci harbored mecA gene. Among tetracycline resistance isolates all of them harbored at least one gene: tet(M), tet(L) and/or tet(K) and 78,9% of them were positive for the Tn916/Tn1545-like integrase family gene. Our results indicated that retail RTE food could be considered an important route for transmission of antibiotic resistant staphylococci harboring multiple antibiotic resistance genes.