bluuebunny/crossref_metadata_2025 huggingface dataset:
Phytocannabinoids use in Alzheimer’s disease
Authors: Seixas Júlia Maia , Silva Hygor Kleber Cabral , Lopes Maria Alice Rocha , Camargos Kamila Castro Oliveira , Marques Lara Silveira , Souza Maria Tereza Nogueira Fonseca e , Parreiras Bianca Henriques , Hoffmann Alice Carvalho , Jardim Letícia Fernanda Saraiva
Published: December 2021

Background: Alzheimer’s disease (AD) is the most common cause of dementia among older adults impacting quality of life. Nowadays, four drugs are indicated to manage AD symptoms, however, none of them have shown effectiveness to prevent the disease’s progress, and they are associated with adverse effects. In this scenario, the endocannabinoid system has the attention of researchers and physicians, because of its relation with processes involved in the AD physiopathology. Therefore, in the last decade, studies that evaluate the use of Cannabidiol (CBD) and other phytocannabinoids, like tetrahydrocannabinol (THC) and cannabinol (CBN), as an alternative treatment to this illness, have multiplied. Objectives: To bring updated information about this new and promising therapeutic. Methods: A bibliographic research in PubMed with the terms “Cannabidiol and Alzheimer” was made, with the filters “Free full text” and “Publication Date 5 years”. The research obtained 31 results, from which were chosen 10. Results: In vivo studies with CBD, THC and CBN have shown their properties: anti-inflammatory, antioxidant, attenuation of toxic accumulation of β-amyloid protein and to reverse cognitive deficits, all AD physiopathological processes. It was also demonstrated that the combination between THC and CBD shows better efficiency and fewer adverse effects than CBD isolated use. Conclusions: Despite needing deeper and stronger studies with better conducted clinical trials, the researches about phytocannabinoids use in AD seem promising, and they might become the biggest ally in the treatment of this and other neurodegenerative conditions.
Predictors of functional dependence at hospital discharge in a stroke unit
Authors: Rocha Isadora Souza , Santos Paola Nabhan Leonel dos , Küster João Guilherme Bochnia , Lizama Maria Angélica Vieira , Giugno Vinícius Riegel , Teive Hélio Afonso Ghizoni , Raskin Salmo
Published: December 2021

Introduction: Functional dependence is a common condition poststroke. The specialized care offered at the stroke unit can provide patients with better rehabilitation. We designed a study to evaluate risk factors for functional dependence at hospital discharge in a stroke unit. Design and setting: Prospective cohort study at Hospital Geral Roberto Santos. Methods: Patients were admitted within 72h of ictus. Functional dependence was defined as scores 3-5 on the modified Rankin Scale (mRS). Results: 389 patients were enrolled, with a mean age of 59.3 (±17.9) years, of whom 55.8% were men. The frequency of functional dependence at discharge was 57.1%, 50.3% at 30 days, and 38.8% at 90 days of the ictus. Higher risk of dependence at hospital discharge were associated with stroke recurrence [RR 1.2 (1.0 - 1.5)], polypharmacy [RR 1.3 (1.1 - 1.6)], female sex [RR 1.3 (1.1 - 1.6)], hemorrhagic stroke [RR 1.4 (1.2 - 1.7)], large artery atherosclerosis by TOAST [RR 1.6 (1.2 - 2.0)], hemorrhagic transformation [RR 1.57 (1.3 - 1.9)], infection [RR 1.7 (1.5 - 2.0)] and delirium [RR 1.8 (1.5 - 2.0)] during hospitalization. Conclusions: We have demonstrated a high frequency of functional dependence at hospital discharge from the stroke unit. Understanding which patients may have a worse functional outcome can be a good strategy to articulate access to the rehabilitation.
Hirayama Disease: Case report of a rare case in Brazil
Authors: Resende Larissa Damian , Pinto Thiago de Abreu Silva , Carneiro Henrique Marreiros Veloso , Prado Fellype Matos do
Published: December 2021

Context: Hiravama’s disease (HD) is a rare neurological condition described by keizo Hirayama in 1959, in which growth of the content of the spinal canal displaces the posterior dural sac previously when flexing the neck at the level of C7 and T1. Thus, it generates ischemic damage in the cells of the anterior spine. In this context, we present a case report about the disease. Case report: Male, 13 years old, complaining of difficulty in grasping his right hand for 5 months and atrophy in his right upper limb for 1 month. On physical examination, the neurological changes found were: Decreased strength of the right upper limb distally, the deep hypoactive reflexes in both upper limbs. Magnetic resonance imaging of the flexed cervical spine showed stenosis of the C5 to T1 spinal canal, flow-voids prominence in the posterior epidural space (suggestive of venous engorgement), tapering and alteration of T2 signal in the C5-C6 medulla. These findings and along with the clinical history confirmed the diagnosis of HD. Conclusion: HD is a rare disease that needs to be known. Thus, the present study expands the database about the disease, which if diagnosed early, improves the patient’s prognosis.
Modulation of gene transcription promoted by mesenchymal stem cells on cation-chloride cotransporter NKCC1 in experimental epilepsy
Authors: Zocche Junior Giovani , Ghilardi Isadora , Provenzi Laura , Leal Gabriel , Pinzetta Giulia , Becker Nicole , Pimentel Vitoria , Marinowic Daniel , Zanirati Gabriele , Zanatta Angela , Rodrigues Felipe , Costa Jaderson Costa da
Published: December 2021

Introduction: temporal lobe epilepsy is a disorder in which synchronized and rhythmic neural firing causes spontaneous recurrent seizures (1). Refractoriness due to this condition reaches 30% of its carriers (2,3). The search for therapeutic alternatives to help cope with this disease are extremely important. Mesenchymal stem cells (MSCs) appear as a plausible treatment option, as they present a less invasive approach and due to their niche modulating character (4,5). Objectives: this study aimed to quantify the gene expression of cation-chloride cotransporter NKCC1 encoded by the SLC12A2 gene in the encephalic tissue of pilocarpine-induced epileptic rats (6,7). Design: experimental study, brain institute of Rio Grande do Sul. Methods: MSCs were obtained from the bone marrow of Wistar rats, cultured, and transplanted through intravenous injection into control and epileptic Wistar rats. The rats were divided between control group, MSCs treated group, and pilocarpine group, containing 8 individuals each (8). Expression analysis was performed using real-time polymerase chain reaction. Results: for both 1 day and 7 days post-transplantation, an increase in the NKCC1 expression in both control and epileptic treated groups as compared to its expression in untreated epileptic and control groups with special attention to the amygdala, the hippocampus and the prefrontal cortex. Conclusion: MSCs stimulated expression of NKCC1 in brain structures of rats induced by pilocarpine to epilepsy. This corroborates the hypothesis of neuroprotective effects and modulating properties of stem cells and may point to more mechanisms for investigating the functioning and collaboration of these cells as a treatment for epilepsy.
Does hemorrhagic transformation in patients with ischemic stroke predict worse functional outcomes?
Authors: Silva Ivã Taiuan Fialho , Mendez Vinícius Bessa , Abreu Fernanda Ferreira de , Cajaíba Alice Monteiro Soares , Jesus Pedro Antonio Pereira de
Published: December 2021

Background: Hemorrhagic transformation (HT) is a complication of stroke described as cause of early neurologic deterioration. Previous studies are discordant about the real impact of HT on stroke prognosis. Objectives: to describe the impact of HT in patient prognosis. Design and setting: Prospective cohort with acute ischemic stroke patients from a Stroke Unit, admitted between 2017 to 2020. Methods: All patients performed a brain computer tomography (CT) scan on their arrival and 24 hours later. Patients with or without HT were compared regarding functional 90-day outcome using the modified rankin scale (mRS). Functional disability was considered as mRS < 2. Results: 383 patients were included, mean age was 62,2 (±13,8), which 54,3% were male, 80,9% hypertensive, 33,1% diabetics and 27,2% were dyslipidemic. HT occurred in 11,5% patients (n= 44) increasing the risk of poorer functional outcome in discharge [RR= 1,47; (IC95% 1,25–1,72), in 30 days [RR = 1,54; (IC95% 1,01-1,92)], and in 90 days [RR= 1,39; (IC95% 1,01-1,92)]. Multivariate analysis HT was not associated with worse outcome in 90 days (mRS>2) [OR= 1,01; (IC95% 0,44–2,33) p= 0,987], when adjusted to age, sex, NIHSS, ASPECTS, trombolysis and other relevant variables. Conclusion: Although the occurrency of HT had been associated with worse short-term outcomes, patients seems to recover from disability over time.
Progressive myoclonic epilepsy: case report
Authors: Santos Maria do Carmo Vasconcelos , Sa Mariana Moreira Soares de , Barreto Emanuelle Ferreira , Moraes Aline Cursio , Guimarães Roberta Kelly Netto Vinte , Gomes Neto Antonio Pereira
Published: December 2021

Context: Progressive myoclonic epilepsy (PMS) begins in childhood or during adolescence, being a heterogeneous group of symptomatic progressive progressive generalized epilepsy. Composed of cortical myoclonus, multiple epileptic seizures, delayed or regressed neuropsychomotor development and cerebellar manifestations. Genetics is heterogeneous with a similar clinical presentation, which makes etiological definition difficult. Report a clinical case of generalized epilepsy, myoclonus, cerebellar condition and severe mental impairment. Analysis of medical records of a patient at Santa Casa de Belo Horizonte. Case report: MVPP, 17 years old, previously healthy, adopted son, normal neuropsychomotor development, first generalized tonic-clonic seizure at 8 years old, recurrence at 12 years old, being initiated by Valproato and Clobazam. In 2018 there was a worsening of the crises, perceived myoclonus, added Lamotrigine and Oxcarbazepine. EEG with continuous diffuse epileptic activity of subclinical epilepticus status and unchanged skull MRI. In 2019 he started with gait ataxia, balance changes, dysarthria, dysmetria, cognitive decline, loss of functionality and refractoriness to treatment. Valproate reduced and oxcarbazepine suspended. Video- EEG with ictal pattern of generalized wave polyspicle. Deteriorated cerebellar condition with extensive propaedeutic without alterations. There was no feasibility of genetic testing at the time. Methylprednisolone pulse therapy with partial improvement. Unsuccessful attempt to levetiracetam due to psychotic symptom. He presented lowering of the sensorium, bronchoaspiration and orotracheal intubation. He evolved with myoclonic status, adjusted for anti-crisis drugs, midazolam, thiopental, tracheostomy and gastrostomy. He maintained super- refractory status, being opted for callosotomy. He died within weeks of the procedure. Conclusion: The early diagnosis of PMS is a challenge, and its evolution is usually debilitating, with a poor prognosis and scarce specific treatment. Whenever possible, a genetic study is needed to define an etiological diagnosis.
Capacitación de la práctica de higiene de manos mediante un curso en línea dirigido al personal de salud de un hospital de segundo nivel de atención de Toluca, México
Authors:   Facultad de Medicina, Campus Universitario Siglo XXI, Romero Figueroa María del Socorro , Romero Rojas Enrique ,   Facultad de Medicina, Campus Universitario Siglo XXI
Published: December 2021

El objetivo del estudio fue determinar si la capacitación mediante un curso en línea de la estrategia Multimodal de la OMS mejora el cumplimiento de higiene de manos del personal de salud en un hospital. Se llevó a cabo un estudio cuasi-experimental que incluyó 600 médicos y enfermeras de un hospital de segundo nivel de atención, en él se usó como maniobra de intervención un curso en línea de higiene de manos y una evaluación de conocimientos al inicio y al final del curso, además se identificó el número de oportunidades para practicar la higiene de manos y su cumplimiento. Durante 15 meses de seguimiento se detectaron 17 763 oportunidades para la higiene de manos, un cumplimiento total de 7434 acciones en ese periodo, y una brecha del 41.1% entre el primer y el quinto semestre. Los resultados arrojaron una mejora del promedio de conocimientos de 15 puntos (76.1 pre y 91.1 postprueba) con una diferencia significativa P≤ 0.001. A nivel mundial el apego a la práctica de higiene de manos constituye un desafío, a pesar de que los profesionales de la salud conocen la problemática que se genera por la falta de esta actividad. El estudio permitió determinar que la utilización de diferentes estrategias en la educación continua es indispensable para mejorar los estándares de atención.
Análise espaço-temporal da evolução da vulnerabilidade costeira em Itapoá - Santa Catarina
Authors: Silva Ariana , Suski Cassio
Published: December 2021

A erosão costeira é um processo de ordem natural, principalmente em praias arenosas. As praias arenosas são comuns no Brasil e, geralmente a população em sua maioria encontra-se localizada nessa região onde, como consequência, diversos riscos estão associados a esse processo. O ambiente litorâneo possui muita importância econômica e ao mesmo tempo é um ambiente complexo em seus processos naturais e extremamente sensíveis. Por isso, diversos autores buscam por métodos de análise da variação da linha de costa para a obtenção de informações sobre o avanço, que resulta nos processos erosivos, a fim de identificar a vulnerabilidade costeira. Atualmente a instalação de contenções e obras como a engorda de praia tem sido comum, principalmente em regiões de extrema importância econômica. Neste trabalho, a modelagem numérica MOHID será utilizada para obtenção do balanço hidrodinâmico e sedimentar das praias de Itapoá-SC em junção com análises climáticas a fim de identificar quais os processos que estão ocasionando déficit no aporte sedimentar da região, o qual está resultando em processos erosivos de grande intensidade na porção sul das praias.
DATA VISUALIZATION OF COVID-19 DATA USING TABLEAU
Authors: Singhal Nirmit , Goel, Amita , Sengar Nidhi , Bahl Vasudha
Published: December 2021

The world generated 52 times the amount of data in 2010 and 76 times the number of information sources in 2022. The ability to use this data creates enormous opportunities, and in order to make these opportunities a reality, people must use data to solve problems. Unfortunately, in the midst of a global pandemic, when people all over the world seek reliable, trustworthy information about COVID-19 (Coronavirus). Tableau plays a key role in this scenario because it is an extremely powerful tool for quickly visualizing large amounts of data. It has a simple drag-and-drop interface. Beautiful infographics are simple to create and take little time. Tableau works with a wide variety of data sources. COVID-19 (Coronavirus)analytics with Tableau will allow you to create dashboards that will assist you. Tableau is a tool that deals with big data analytics and generates output in a visualization technique, making it more understandable and presentable. Data blending, real-time reporting, and data collaboration are one of its features. Ultimately, this paper provides a clear picture of the growing COVID19 (Coronavirus) data and the tools that can assist more effectively, accurately, and efficiently. Keywords: Data Visualization, Tableau, Data Analysis, Covid-19 analysis, Covid-19 data
A REAL – TIME SYSTEM FOR RECOGNITION OF AMERICAN SIGN LANGUAGE BY USING DEEP LEARINING
Authors: Panwar Mohit , Pandey Rohit , Singla Rohan , Saxena Kavita
Published: December 2021

Every day we see many people, who are facing illness like deaf, dumb etc. There are not as many technologies which help them to interact with each other. They face difficulty in interacting with others. Sign language is used by deaf and hard hearing people to exchange information between their own community and with other people. Computer recognition of sign language deals from sign gesture acquisition and continues till text/speech generation. Sign gestures can be classified as static and dynamic. However static gesture recognition is simpler than dynamic gesture recognition but both recognition systems are important to the human community. The ASL American sign language recognition steps are described in this survey. There are not as many technologies which help them to interact with each other. They face difficulty in interacting with others. Image classification and machine learning can be used to help computers recognize sign language, which could then be interpreted by other people. Earlier we have Glove-based method in which the person has to wear a hardware glove, while the hand movements are getting captured. It seems a bit uncomfortable for practical use. Here we use visual based method. Convolutional neural networks and mobile ssd model have been employed in this paper to recognize sign language gestures. Preprocessing was performed on the images, which then served as the cleaned input. Tensor flow is used for training of images. A system will be developed which serves as a tool for sign language detection. Tensor flow is used for training of images. Keywords: ASL recognition system, convolutional neural network (CNNs), classification, real time, tensor flow
Atributos físicos e químicos de solos sob diferentes tipos de uso e manejo no assentamento Abril Vermelho, Amazônia Oriental
Authors: Melo Vânia Silva de , Marques Jonathan Dias , Silva Júnior Mário Lopes da , Meyer Leandro Frederico Ferraz , Dias Victor Henrique Rodrigues , Aguiar Thamyres de Souza , Teixeira Orivan Maria Marques
Published: December 2021

Este trabalho tem como objetivo avaliar as alterações nos atributos físicos e químicos do solo do assentamento Abril Vermelho, em função dos diferentes tipos de uso da terra e cobertura vegetal. Foram selecionadas cinco áreas, quatro sob diferentes tipos de uso e manejo (sistema agroflorestal, plantio de açaí, pastagem e plantio de mandioca), e uma área de referência (floresta secundária). Em cada área foram coletadas amostras de solo nas profundidades de 0-5, 5-10 e 10-20 cm, com quatro repetições, totalizando 60 amostras deformadas e 60 indeformadas para análise de densidade do solo (Ds). Os valores de pH (H2O), Al3+ (alumínio trocável), H+Al (acidez potencial) e M.O (matéria orgânica) sofreram alterações tanto entre os sistemas de uso do solo, quanto em razão da profundidade do perfil. No sistema em que houve trituração e disposição da biomassa no solo (plantio de mandioca), houve melhoria da qualidade do solo, com o aumento de 41% do teor de M.O em comparação ao sistema de referência, e também na manutenção da Ds próximo aos valores da capoeira. A Ds e M.O destacam-se por detectar as alterações na qualidade do solo em função da mudança de cobertura vegetal na maioria dos sistemas de uso dos solos estudados.
Approach to Humeral Shaft Nonunion: Evaluation and Surgical Techniques
Authors: Naclerio Emily H. , McKee Michael D.
Published: December 2021

Humeral shaft fractures account for 1% to 3% of all fractures. Traditional nonsurgical treatment with a functional brace is still the standard treatment of these fractures; however, modern studies have reported that nonunion rates may be as high as 33%. Recent information suggests that the development of nonunion after nonsurgical treatment may be identified as early as 6 to 8 weeks postinjury. Even with surgical treatment, nonunion rates as high as 10% have been reported. Regardless of the original treatment method, nonunion results in poor quality of life for the patient and therefore should be addressed. A thorough preoperative evaluation is important to identify any metabolic or infectious factors that may contribute to the nonunion. In most cases, surgical intervention should consist of compression plating with or without bone graft. Although most patients will achieve union with standard surgical intervention, some patients may require specialized techniques such as cortical struts or vascularized fibular grafts. Successful treatment of humeral shaft nonunion improves function, reduces disability, and improves the quality of life for patients. In this article, we outline our approach to the treatment of humeral shaft nonunion in a variety of clinical settings.
Influence of Initial Conditions at Nozzle Section on Flow Structure and Instability of Plane Jet
Authors: V. Kozlov Grigory , R. Grek Genrich , M. Sorokin Aleksandr , A. Litvinenko Yuriy
Published: December 2021

Experimental data concerning the influence of initial conditions at the nozzle exit on the structure and development characteristics of plane jet are reported. Features in the development of laminar and turbu-lent round jets emanating from variously elongated nozzles at identical Reynolds numbers are revealed. Smoke visualization pictures obtained for jets formed under different initial conditions (with different distributions of mean and pulsating flow velocities at the nozzle exit), influence of acoustic and interac-tion of streaky structures with vortex trail of laminar plane jet are discussed. It is established that, the laminar and turbulent jet on an output of the plane channel of Hagen-Poiseuille undergoes sine wave os-cillations, as a single whole. It is established that, the symmetric mode of instability of a laminar plane jet are suppressed asymmetrical. It is shown that, interaction of the streaky structures generated on one side of plane nozzle, with vortices of a laminar plane jet with a parabolic velocity profile leads to appearance of Λ- or Ω-vortices on vortices of a vortex trail, on the right as well as on the left side of the nozzle.
Origin of the Nucleation Rate Empirical Data Inconsistencies for the Vapor-Gas Systems
Authors: A. Volf Anna , G. Fominykh Elena , P. Anisimov Mikhail
Published: December 2021

Independent results for vapor nucleation rates illustrate the nucleation rates inconsistencies for identical vapor-gas systems at the same conditions. Nature of these inconsistencies is not yet understood enough. Assumption is discussed that a reason for the experimental data inconsistencies is appeared in the result of the carrier gas effects on nucleation. It was supposed for a long time that any carrier gas is an ambient atmosphere to keep the nucleation temperature only. The recent experimental results have shown that a vapor-gas nucleation needs to be treated in approximation of binary solutions, i. e. a composition axis is appeared in addition to axes of nucleation rate versus pressure. Each single line of a nucleation rate isotherm is transformed to surface in a three dimensional space of nucleation parameters. Flow diffusion chamber and expansion Wilson type set up data comparison are discussed on the example of the published empirical data. It was shown using a model system that these two experimental realizations produce the inconsistent trajectories in the space of nucleation parameters. That misfit induces the different origin data inconsistencies and demonstrates relevance of gas treatment as an individual component of a nucleating vapor-gas system.
The Kinetics of (2×4) --> (3×1(6)) Reconstruction Transition on GaAs Surface
Authors: V. Vasev Andrey , А. Putyato Mikhail , R. Semyagin Boris , V. Preobrazhenskij Valeriy
Published: December 2021

The features of (2×4) --> (3×1(6)) superstructure transition on GaAs(100) surface realized during rapid change of arsenic flux density were studied using RHEED method. The time dependences of ISB RHEED were obtained during this transition. The measurement data were analyzed in the framework of JMAK (Johnson – Melh – Avrami – Kolmogorov) kinetic model. The complex (double-state) structure of the transition process has been detected. This process is realized through the intermediate disordered state with different reconstructions domains coexisting on the surface. Activation energies and rates of the phase transition are defined for each stage. The procedure for precise temperature determination for GaAs(001) surface is proposed. This procedure uses the features of (2×4) --> (3×1(6)) reconstruction transition kinetics.
Using of Lock-In Amplifier for Thermal Expansion Measurements of Solids
Authors: R. Zhdanov Kamil , B. Amitin Evgeny , K. Zhdanov Ravil
Published: December 2021

This paper describes simple electrical scheme for dilatometric researching. Using phase-sensitive AC voltmeter SR830 and digital DC voltmeter Solartron 7061 give full set of requed data.
Fast Fourier Transform – Calculation and Interpretation
Authors: A. Knyazev Boris , S. Cherkasskij Valeriy
Published: December 2021

The article is intended to the students, who make their first steps in the application of the Fourier transform to physics problems. We examine several elementary examples from the signal theory and classic optics to show relation between continuous and discrete Fourier transform. Recipes for correct interpretation of the results of FDFT (Fast Discrete Fourier Transform) obtained with the commonly used application programs (Matlab, Mathcad, Mathematica) are given.
Impact of the Reconstruction Condition on Gallium Arsenide Surface Morphology during Molecular-Beam Epitaxy and Vacuum Annealing
Authors: V. Vasev Andrey , А. Putyato Mikhail , R. Semyagin Boris , A. Seleznev Vladimir , V. Preobrazhenskij Valeriy
Published: December 2021

The peculiarities of morphological evolution during GaAs(001) molecular beam epitaxy are studied by RHEED and AFM methods. A clear correlation is established between surface superstructure and morphological evolution. Thermodynamic conditions are experimentally determined which provide the most perfect GaAs(001) epilayer surface. For the (2 × 4) surface reconstruction growth conditions are established which give rise to surface roughening. A new technique is proposed and tested to significantly increase the efficacy of surface smoothening procedure under As flux.
Study of Microinstabilities in Anisotropic Plasmoid of Thermonuclear Ions
Authors: S. Korzhavina Mariya , V. Anikeev Andrey , A. Bagryansky Petr
Published: December 2021

The following article presents the results of investigation of microinstabilities in the anisotropic synthesized hot ion plasmoid (SHIP). Plasmoid is located in a small mirror section that is installed at one side of the GDT facility in Budker Institute of Nuclear Physics, Novosibirsk, which is an axially symmetric magnetic mirror device of gas dynamic trap type. The magnetic field on axis is in the range of 2.5 Tesla and the mirror ratio is ~ 2. The additional mirror section is filled with background plasma streaming from the central cell of GDT. To create the population of hot ions with strong anisotropy two focused neutral beams with energy of 21–23 keV are injected perpendicularly to the direction of magnetic field. Ionisation of the beams generates the high-energetic ion component with the density of about 5x1013 сm–3 and mean energy about 13 keV. The distribution function of fast ions is thus strongly anisotropic in the phase space with the ratio E⊥ / E& ~ 50. To define the type and the parameters of the developing microinstability a set of high-frequency electrostatic and magnetic probes was used. The microinstability observed in the additional section of GDT is the Alfven ion cyclotron instability (AIC), because of small azimuthal wave numbers, magnetic field vector rotating in the direction of ion gyration and oscillation frequency below the actual ion cyclotron frequency. AIC instability threshold was registered at the following plasma parameters: fast ion density n > 3 · 1013 см–3, ratio of ion pressure to magnetic field pressure β ≈ 0.02, anisotropy A ≈ 35, ai / Rp ≈ 0.23, where ai is the ion gyroradius and Rp is the plasmoid radius.
A Beam Extraction Scheme From a Booster Synchrotron of Novosibirsk Sr Source
Authors: Bondarenko Alexey , Vinokurov Nikolay , Miginky Sergey
Published: December 2021

A beam extraction scheme from a cyclic accelerator is put forward. Its main difference from other schemes of extraction is the use of magnetic shields instead of a septum-magnet. Magnetic shields are located in the central dipole magnets of a pulsed chicane. The proposed scheme will be used for vertical extraction from a booster synchrotron to a storage ring in a new synchrotron radiation source in Novosibirsk.
Dynamics of Shock Waves in the Cylindrical Channel With Confusers
Authors: Anufriev Igor , Golovanov Aleksandr , Tsimbalyuk Aleksandr , Sharypov Oleg
Published: December 2021

Current work covers experimental and theoretical investigation of conic confusers impact on the intensity shock wave, generated in the shock tube by explosion of gunpowder charge. For given conditions optimal geometric characteristics of the confuser, providing maximal pressure in the shock wave front, were found experimentally. The mathematical model was developed and numerical simulation of the axisymmetric shock-wave gas flow in the channel was carried out. Experimentally was shown, that the application of the optimal confuser provides significant increase of the efficiency gasdynamic effect on the combustion of forest combustible materials.
High-Temperature Coulomb Blockade
Authors: Pogosov Artur , Budantsev Maxim , Shevyrin Andrey , Plotnikov Alexey , Bakarov Ashat , Toropov Aleksandr
Published: December 2021

The Coulomb blockade effect is studied in a single-electron transistor – quantum dot, separated from source and drain areas by tunnel junctions. Peculiarity of the transistor is that it is made on the basis of semiconducting membrane, separated from the suffer. Separating the transistor from the suffer having high dielectric constant leads to the drastic decrease in the quantum dot capacity С and, therefore, to the increase in the Coulomb gap 2 e C/ . This value is important since it determines the upper limit of the transistor working temperature. A direct comparison of the Coulomb gaps before and after separating from the suffer shows that it increases from 40 K (in temperature units) for conventional transistor to 150 K for the «suspended» one. High value of the Coulomb gap has made it possible to observe clear diamond-like structure of condactance dependence on the gate and source-drain voltages, specific for the Coulomb blockade, while typical temperature of this kind of measurements on conventional single-electron transistors is about hundreds of millikelvins. An additional blockade effect, different from the conventional Coulomb blockade is observed. The nature of this effect can be connected with additional mechanical degrees of freedom of the transistor (elastic deformations).
Features of Performing High-Temperature Chemical Reactions Under Microwave Irradiation
Authors: Bolotov Vasily , Chernousov Yuriy , Udalov Evgeny , Tanashev Yuri , Parmon Valentin
Published: December 2021

The main features of performing the chemical reactions, which take place with heating of reagents under microwave irradiation, are examined. Relationships for calculation of the efficiency of transformation of microwave energy to heat for different chemical objects in the high-Q cavity are presented. Lab-scale set-up (prototype of chemical reactor with the high-frequency heating) for studying the endothermic chemical reactions has been designed and manufactured. The catalytic thermal decomposition of n-hexadecane has been carried out with the high selectivity of -olefins formation.
Analysis of the racial profile of women with COVID-19: a cross-sectional study about evolution to death of black women in the southeast region of Brazil
Authors: Fonseca Marayah Sampaio Ruas da , Almeida Fernanda Dias Guimarães , Guimarães Gabriel Mendes Moura Ossola , Lima Fabieli Helena Paulo Comeira de , Amaral Samara Jared Mendes , Tokumoto Thais , Belmonte Terezinha de Souza Agra
Published: December 2021

Introduction: The first coronavirus disease (COVID-19) case in Brazil was registered in December 2019. Since then, an important social situation has been highlighted. Black women correspond to the highest death rate, by group, in the Southeast even not occupying the highest percentage of diagnosis. This scenario was also experienced in other places around the world. Therefore, some questions must be highlighted, such as social and economic vulnerability of black population in brazilian territory, less access to health service and testing for Covid-19. Objective: This study analyzed the clinical picture and evolution - cure or death-of black women with COVID-19 in the Southeast region. In addition, consolidating knowledge about the factors that precede death in black women and comparing them with other race groups. Methods:  Cross-sectional study with data from the Ministry of Health's Severe Acute Respiratory Syndrome (SARS) from March to November 23, 2020, with a total number of women classified as level 5, with SARS caused by the virus SARS-Cov-2, equal to 33,991, being 21,551 white and 12,063 black. Results and Conclusion: Therefore, black women present themselves as a vulnerable group in relation to COVID-19. This group was less present in the ICU, but both groups, white and black women, had dyspnea as an aggravating factor. Considering those facts, it's possible that black women had less access, this would explain a greater number of deaths among this group compared to white women, which could signify a failure in the health care of this population. When analyzing deaths by age group, it is evident that white women followed the literature pattern - severe forms occur in patients over 65 years of age with comorbidities, while there was a rejuvenation of deaths among black women. It is a limitation of our study not to include comorbidities in the analysis. This situation becomes relevant for directing public policies that aim to reverse the factors associated with this situation. More studies are needed to elucidate the socioeconomic issues that support this outcome, seeking to reduce the number of deaths from COVID-19 in black women.
Student Opinions and Suggestions about Distance Education
Authors: ÇELEBİ Celalettin , YILMAZ Fatih
Published: December 2021

The coronavirus pandemic, which emerged in 2019 in the city of Wuhan, China, affected societies very quickly. It has brought about important changes in many fields such as economy, health systems, education and so on. In order to prevent losses in education and adapt to this new situation, countries quickly switched from face-to-face education to distance education. This study, aiming to examine the opinions and suggestions of high school students about the compulsory distance education activities during the Covid-19 pandemic, is a phenomenological study designed in the qualitative research design. The participants of the study have been determined by purposeful sampling method and the data have been collected through a fixed format questionnaire. 151 high school students participated in the study which was carried out between May and June, 2021. The data have been analyzed using the descriptive analysis and content analysis techniques. The results show that high school students experienced various problems such as the internet connection problems, software and hardware problems required for the access, communication problems, motivational problems and so on. However, they got support from their families during this time, and apart from the factors negatively affecting their motivation, there were some factors affecting their motivation positively. They also offered some suggestions for the solution of problems encountered.
modelo de red neuronal para el Indice de Producción de la Construcción Total en España
Authors: Alonso-Rodríguez Agustín
Published: December 2021

Con los datos del Indice de la Construcción Trimestral Total en España, se establece un modelo de red neuronal para visionar el futuro de la construcción desde el tercer trimester de 2019 hasta el segundo cuatrimestre de 2022.
Metamorfosis del mundo del trabajo.
Authors: Montalvo Josefa
Published: December 2021

Los avances tecnologicos, las nuevas necesidades del mercado y los intereses sectoriales son algunos de los factores que estan transformando el mundo del trabajo. En este contextom, México obligado por circunstancias comerciales y ante la amenaza de no ratificar el acuerdo comercial T-MEC por parte de Estados Unidos, promovio una reforma laboral donde se establece un nuevo sistema de justicia en la materia buscando el cumplimiento efectivo de derechos laborales internacionalmente reconocidos, haciendo enfasis en la no discriminación, la no violencia en los ecentros de trabajo yla igualdad de genero.
HYPERCASUAL OYUNLARI SADECE GENÇLER Mİ OYNAR? OYUNCULARIN DEMOGRAFİK ÖZELLİKLERİ ÜZERİNE BİR DEĞERLENDİRME
Authors: TAŞ Cihan Yavuz , TAŞ Nur Billur
Published: December 2021

Teknolojinin gelişmesi ve bilgisayar teknolojilerinin hayatın her kademesine dahil olması ile birlikte video oyunlar da hayatın ve sosyalleşmenin bir parçası haline gelmiştir. Sofistike strateji oyunlarından basit telefon uygulaması oyunlara kadar çok geniş bir spektrumda olan video oyunlarının kullanıcıları da sanıldığı gibi teknoloji içine dünyaya gözlerini açan Z kuşağı değildir. Günümüzde okul öncesi çocuklardan gençlere, orta yaştan ileri yaş grubuna kadar birçok birey video oyunları ile zaman geçirme, sosyalleşme ve kendini geliştirme çabası içindedir. Değişen sosyal hayat koşulları, teknolojinin bir araya gelmeden de iletişimi mümkün kılması gibi nedenlerle, bireyler sosyalleşmede daha fazla bilgisayar teknolojilerini kullanırken, video oyunları da yıllar içinde giderek daha fazla rağbet görmeye başlamıştır. Gelişmiş konsollar yanında telefon uygulamaları üzerinden kolaylıkla indirilebilen basit mobil oyunlar dünyanın her yanında giderek daha fazla kullanıcıya hitap etmektedir. Bu çalışmada basit (hypercasual) oyunları oynayan bireylerin demografik özellikleri, farklı kaynaklardan elde edilen veriler üzerinden analiz edilecektir. Çalışmada elde edilen bulgulara göre, bu oyunlar çocuk ve gençlerden çok orta ve ileri yaş grubu kullanıcılar tarafından oynanmaktadır. Bu çerçevede bu çalışma, hypercasual oyunların tarihçesi, küresel ölçekte ve yerelde kullanım düzeyleri, kullanıcıların demografik özellikleri analiz edilerek değerlendirilecektir. Elde edilen bulgular, bu sektörde teknoloji geliştirme çalışmaları yapan bilim insanları ve piyasa oyuncularının hizmetine sunulacak ve çalışmanın son bölümünde kullanıcı profillerinin geliştirilmesine yönelik politika önerileri de yer verilecektir.
Investigation of the Effect of Turkish Tv Series Watched by Arab Tourists on their Preference for Visiting Turkey
Authors: ÖZDEMİR Nurcan
Published: December 2021

Turkish TV series are broadcast in many continents from the Middle East to the Balkans, Africa to Central Asia, the Far East and South America, and are watched by 700 million people in about 156 countries. In this respect, TV series have become one of the effective soft power tools of Turkey in different parts of the world. The adventure of Turkish TV series to conquer the world is an important issue that increases the material and moral gains of Turkey day by day, and thus they should be prioritized. In this study, it was aimed to determine the effect of the Arab people’s attitude towards Turkish series and their perception of the image of the Turkey on their preference for visiting Turkey. It is a known fact that TV series and movies have the power to direct the society and create awareness. In the current study, Turkey was evaluated as a rising soft power that can play an active role in the regional and global arena through its various soft power sources such as its culture, values, foreign policy and economic success, and the effects of Turkish TV series on Arab people and especially the effects of their attitudes towards the TV series and perceptions of the image of the country on their preference for visiting the country were aimed to be examined. To this end, a survey was conducted on 500 Arabs who came to Turkey for touristic purposes. As a result of the analyses, a statistically significant positive relationship was determined between the attitudes towards Turkish TV series and Turkey’s image and the effect of Turkish TV series on the participants’ preference for visiting Turkey. In addition, Arab tourists’ attitudes towards TV series and their perception of the image of Turkey were found to be varying significantly depending on some demographics.
Presentación
Authors: Agulló Juan , Bruckmann Mónica
Published: December 2021

Pensar la geopolítica mundial en pleno curso de la mayor epidemia de los últimos 100 años exige, sin dudas, un gran esfuerzo analítico y teórico que permita observar los movimientos históricos de larga duración y, al mismo tiempo, los fenómenos de la coyuntura que surgen producto de esta crisis sanitaria que ha sido capaz de impactar absolutamente todas las dimensiones de la vida social y económica en el planeta.
COVID-19 conspiracy beliefs among Romanian university students
Authors:   Faculty of Social Sciences and Humanities, “Lucian Blaga” University of Sibiu, Romania, LUP Oana , MITREA Elena Cristina ,   Faculty of Social Sciences and Humanities, “Lucian Blaga” University of Sibiu, Romania
Published: December 2021

This article explores factors that affect the strength of beliefs in COVID-19 conspiracy theories drawing on data collected in an online survey of undergraduate and graduate students from Romanian universities. The results indicate that students with lower socio-economic status, lower levels of news consumption in the wake of the COVID-19 crisis, who rely primarily on information from television and discussions to their peers, as well as those with lower levels of education/analytical skills are more susceptible to endorsing conspiracy theories regarding the origin and the nature of COVID-19. Education, analytical skills, and exposure to high quality media information appear to equip students with the necessary tools to critically assess COVID-19-related conspiracies. Given the link between conspiracy belief and health behaviors in the context of the pandemic, these results point to the importance of analytical skills and media regulation for curbing misinformation in societal contexts of heightened uncertainty, confusion, and existential threat. Keywords: conspiracy beliefs, COVID-19, Romania, Central and Eastern Europe, postcommunism, university students, news consumption, analytical skills, scientific literacy
PERANCANGAN DAN IMPLEMENTASI APLIKASI GO TO SCHOOL (GoS) BERBASIS WEBSITE MENGGUNAKAN PHP
Authors: Nugroho Chatur , Suhendi Suhendi
Published: December 2021

Sistem informasi sekolah saat ini menjadi acuan bagi orang tua dalam mendaftarkan anaknya ke sekolah- sekolah. Sistem yang ada saat ini masih terbilang kurang efektif karena data informasi sekolah yang disajikan masih terpisah-pisah dan harus dilakukan perbandingan secara satu persatu. Dalam hal kenyamanan dan efisiensi hal itu sangat membuat pengguna tidak nyaman dan cenderung lebih memilih cara manual yaitu dengan datang langsung ke sekolah dalam rangka mencari informasi secara detail tentang sekolah yang diminati tersebut. Maka dari itu penulis menyimpulkan bahwa sistem yang ada saat ini dalam penyajian sistem informasi sekolah masih terbilang kurang efektif walaupun sudah bisa diakses melalui internet. Berlandaskan dari pandangan sebelumnya, penulis akan membahas mengenai proses perancangan dan implementasi Aplikasi Go To School (GoS) berbasis website menggunakan PHP dengan metode pengembangan perangkat lunak menggunakan metode waterfall dan didalam pengumpulan data penulis menggunakan metode kuesioner dan wawancara serta melakukan pengujian aplikasi menggunakan Skala Likert dan User Acceptance Testing (UAT). Dari hasil penilitian yang dilakukan penulis, hasil yang ingin didapat adalah Aplikasi Go To School (GoS) bisa digunakan dengan lancar dan menjadi aplikasi yang efektif dalam sistem informasi sekolah.
INTEGRASI NETWORK MONITORING SYSTEM BEBRBASIS NAGIOS DENGAN TICKETING SYSTEM BERBASIS OS TICKET
Authors: Saputra Debi Onas , Saptono Henry
Published: December 2021

INTEGRASI NETWORK MONITORING SYSTEM BEBRBASIS NAGIOS DENGAN TICKETING SYSTEM BERBASIS OS TICKET
PENENTUAN PENERIMA BERAS RASKIN DI KELURAHAN OESAPA BARAT MENGGUNAKAN METODE K-NEAREST NEIGHBOR (KNN)
Authors: Kaesmetan Yampi
Published: December 2021

Rapid technological developments are currently very influential in all areas of work especially in the field ofmapping the location on maps online. Village of West Oesapa, District Kelapa Lima, Kupang is one of thevillages that aspires for the welfare of the community by way of distribution of poor rice aid to the poor in theeconomic field. Raskin rice distribution should be shared equitably and meets the criteria as a poor ricerecipient in the Village of West Oesapa. With KNN method (K-Nearest Neighbor) will count how many people ineach neighborhood would receive help poor rice in accordance with existing criteria, and to determine thepercentage can be seen in the form of a map.
PEMBANGUNAN SISTEM INFORMASI PERTAHANAN SEKOLAH SMA ISLAM AL AZHAR 4 BERBASIS WEB MENGGUNAKAN PHP & MARIADB
Authors: Fajar Anugerah , Imaduddin Zaki
Published: December 2021

SMA Islam Al Azhar 4 Kemang Pratama memiliki bidang organisasi Ketahanan Sekolah atau biasa disebutTANSE yang berfungsi mengelola semua aturan sekolah terhadap murid yang dilaksanan oleh tim TANSEuntuk peningkatan kualiatas perilaku yang baik untuk mendukung Visi dan Misi sekolah SMA Islam AlAzhar 4 Kemang Pratama. Selama ini kegiatan yang ada di TANSEdalam pengelolaan data pelanggaranmurid masih dikelola secara manual dengan menggunakan buku besar, aplikasi Microsoft Word danMicrosoft Excel. Dimana dengan sistem manual dalam pengelolaan data penelitian dan pengabdian dapatmengakibatkan integritas dan keamanan data yang tidak terjamin serta keterlambatan akan informasisehingga permasalahan waktu dan tingkat validitas data ditekan seminimal mungkin. Penelitian inibertujuan untuk membangun aplikasi sistem informasi ketahanan sekolah SMA Islam Al Azhar 4 KemangPratama berbasis web menggunakan PHP & MariaDB. Hasil penelitian ini adalah aplikasi berbasis webdengan beberapa fitur yang dapat membantu mengelola kegiatan TANSE.
Energy expenditure during cardiopulmonary exercise testing
Authors: Do Thanh Tuan , Nguyen Duc Son , Le Dinh Tung
Published: December 2021

Objectives: To determine energy expenditure during cardiopulmonary exercise testing in healthy adults aged 20-60 years old and to determine the correlation between energy expenditure with the duration and the capacity of physical activity. Methods: Thirty-two healthy volunteers aged 20-60 years old (17 males and 15 females) agreed to participate in our study and performed cardiopulmonary exercise testing: resting phase (4 minutes, work rate 0 w), warming-up phase (4 minutes, work rate 0 w, 50-60 rounds per minute), exercise phase (work rate increment 10 watts per minutes, 50-60 rounds per minute) and recovery phase (3 minutes, work rate 0 w, 10-20 rounds per minute). Results and conclusions: Energy expenditure during CPET was 1,03 ± 0,30 MET, 1,97 ± 0,74 MET, 3,48 ± 1,78 MET, 4,57 ± 2,26 in resting, warming-up, exercise, recovery phase, respectively. Maximum energy expenditure during CPET was 4,75 ± 2,17 MET. Energy expenditure is negatively correlated with the duration of physical activity and positively correlated with the capacity of physical activity at 95% confidence interval.
Markov Chain Confidence Intervals and Biases
Authors: Jiang Yu Hang , Liu Tong , Lou Zhiya , Rosenthal Jeffrey S. , Shangguan Shanshan , Wang Fei , Wu Zixuan
Published: December 2021

We derive explicit asymptotic confidence intervals for any Markov chain Monte Carlo (MCMC) algorithm with finite asymptotic variance, started at any initial state, without requiring a Central Limit Theorem nor reversibility nor geometric ergodicity nor any bias bound. We also derive explicit non-asymptotic confidence intervals assuming bounds on the bias or first moment, or alternatively that the chain starts in stationarity. We relate those non-asymptotic bounds to properties of MCMC bias, and show that polynomially ergodicity implies certain bias bounds. We also apply our results to several numerical examples. It is our hope that these results will provide simple and useful tools for estimating errors of MCMC algorithms when CLTs are not available.