bluuebunny/crossref_metadata_2025 huggingface dataset:
The evolution of a pediatric virtual care evaluation framework
Authors: Dulude Catherine , Sutherland Stephanie , Vanderhout Shelley , King Jim , Zuijdwijk Caroline , Major Nathalie , Audcent Tobey , Howley Heather , Cloutier Paula , Buba Melanie , Jain Raagini , Litwinska Justyna , Findlay Leanne , Malic Claudia , Macaulay Karen , Parker Kasey , Kouri Christine , Goldbloom Ellen
Published: June 2022

Background
The use of virtual care has increased dramatically in response to the COVID-19 pandemic, yet evidence is lacking regarding the impact of virtual care on patient outcomes, particularly in pediatrics. A standardized evaluation approach is required to support the integration of virtual care into pediatric health care delivery programs. The objective of this work was to develop a comprehensive and structured framework for pediatric virtual care evaluation. This framework is intended to engage and guide care providers, health centres, and stakeholders towards the development of a standardized approach to the evaluation of pediatric virtual care.
Methods
We brought together a diverse multidisciplinary team, including pediatric clinicians, researchers, digital health leads and analysts, program leaders, a human factors engineer, a family advisor and our manager of health equity and diversity. The team reviewed the literature, including published evaluation frameworks, and used a consensus-based method to develop a virtual care evaluation framework applicable to a broad spectrum of pediatric virtual care programs. We iteratively developed framework components including domains and sub-domains, examples of evaluation questions, measures, and data sources. Team members provided feedback on all components of the framework until consensus was reached. The framework was then applied to an existing virtual care program.
Results
The resulting framework includes four domains (health outcomes, health delivery, individual experience, and program implementation) and 19 sub-domains designed to support the development and evaluation of pediatric virtual care programs. We also developed guidance on how to use the framework and illustrate its utility by applying it to an existing pediatric virtual care program.
Conclusions
This virtual care evaluation framework expands on previously developed frameworks by providing additional detail and a structure that supports practical application. It can be used to evaluate a wide range of pediatric virtual care programs in a standardized manner. Use of this comprehensive yet easy to use evaluation framework will inform appropriate implementation and integration of virtual care into routine practice and support its sustainability and continuous improvement.
Workshop Proceedings: Going Beyond Zoom --- Tips and Tricks for Teaching Horticulture Online
Authors: Nunez Gerardo H. , Anderson Neil O. , Imler Christopher S. , Irish Laura , Miller Chad T. , Neves da Silva Mariana
Published: June 2022

During the 2021 American Society for Horticultural Science annual conference, the Teaching Methods Professional Interest Group hosted the workshop “Going beyond Zoom: Tips and tricks for teaching horticulture online.” This workshop provided a forum for the dissemination of tools, materials, and approaches used to facilitate active learning in horticulture courses. Here we summarize the topics presented in the workshop as a resource for current and future horticulture instructors.
DprE1 inhibitors – a prospective target for development of antituberculosis drugs
Authors: Kukurika A. V.
Published: June 2022

The article reviews and analyzes 63 scientiﬁc publications devoted to new classes of antituberculosis drugs – DprE1 inhibitors. Currently, compounds BTZ-043, PBTZ-169 (makozinone), TBA-7371 and OPC-167832 are tested at diﬀerent stages of clinical trials. DprE1 inhibitors are promising drugs with antituberculosis activity, which requires further clinical trials.
Speciﬁc course of COVID-19 associated pneumonia in the tuberculosis patient after pleuropneumonectomy
Authors: Zhukova E. M. , Laushkina Zh. A. , Skvortsov D. A. , Stavitskaya N. V.
Published: June 2022

The article describes a clinical case of viral pneumonia associated with COVID-19 of the only lung, it developed in the patient 30 days after pleuropneumonectomy which was done to manage ﬁbrous cavernous pulmonary tuberculosis. The favorable course of COVID-19 was due to its timely detection and initiation of treatment, and possibly, it was due to using anti-tuberculosis chemotherapy containing antibacterial drugs that prevented nosocomial infections.
$\mathrm{T}\overline{\mathrm{T}}$-deformed 1d Bose gas
Authors: Jiang Yunfeng
Published: June 2022

\mathrm{T}\bar{\mathrm{T}}TT‾
deformation was originally proposed as an irrelevant solvable
deformation for 2d relativistic quantum field theories (QFTs). The same
family of deformations can also be defined for integrable quantum spin
chains which was first studied in the context of integrability in
AdS/CFT. In this paper, we construct such deformations for yet another
type of models, which describe a collection of particles moving in 1d
and interacting in an integrable manner. The prototype of such models is
the Lieb-Liniger model. This shows that such deformations can be defined
for a very wide range of systems. We study the finite volume spectrum
and thermodynamics of the \mathrm{T}\overline{\mathrm{T}}TT¯-deformed
Lieb-Liniger model. We find that for one sign of the deformation
parameter (\lambda<0)(λ<0),
the deformed spectrum becomes complex when the volume of the system is
smaller than certain critical value, signifying the break down of UV
physics. For the other sign (\lambda>0)(λ>0),
there exists an upper bound for the temperature, similar to the Hagedorn
behavior of the \mathrm{T}\overline{\mathrm{T}}TT¯
deformed QFTs. Both behaviors can be attributed to the fact that
\mathrm{T}\overline{\mathrm{T}}TT¯
deformation changes the size the particles. We show that for
\lambda>0λ>0,
the deformation increases the spaces between particles which effectively
increases the volume of the system. For \lambda<0λ<0,
\mathrm{T}\overline{\mathrm{T}}TT¯
deformation fattens point particles to finite size hard rods. This is
similar to the observation that the action of
\mathrm{T}\overline{\mathrm{T}}TT¯-deformed
free boson is the Nambu-Goto action, which describes bosonic strings —
also an extended object with finite size.
A PROSPECTIVE STUDY FOR EVALUATION OF FUNCTIONAL OUTCOMES OF PLATE OSTEOSYNTHESIS FOR CLOSED INTRAARTICULAR CALCANEAL FRACTURES
Authors:   M.s. Orthopaedics, Associate Professor., Peepra Digember , Naik Sparsh ,   M.s. Orthopaedics, Assistant Professor., Vidyarthi Ashok ,   M.s. Orthopaedics, Professor and Head of Dept.Of Orthopaedics., Kumar Pradhan Chinmaya ,   M.s. Orthopaedics, Professor and Head of Dept.Of Orthopaedics.
Published: June 2022

Background: Calcaneal fractures account for 65% of tarsal injuries most (70%) of them are intra articular. It is the most repeatedly fractured tarsal bone. Axial loading is the most common mode of injury,falls from height, especially in male construction workers are the most frequent cause. Other fractures associated with falls from height have to be excluded such as pelvic and spinal fractures. Aims and Objective: To analyze the functional outcome of closed displaced intraarticular calcaneal fractures treated by plating. Materials and methods:This is a prospective study of 16 patients with displaced intraarticular fractures (Typeâ€“II Sanders and above) of calcaneum, which were admitted to the hospital and operated on with platingthrough extensile lateral approach, between November 2019to October 2021. Result: In our study functional outcome according to the AOFAS(American Orthopaedic Foot And Ankle Society) score was Good(>75) in 14 cases(87.5%) and Fair(50-74) in 2(12.5%) and mean AOFAS score is 87.123. Conclusion: Open reduction and internal fixation of displaced intra-articular calcaneal fractures by locking calcaneal plate maintain the joint congruity and decrease the incidence of subtalar arthritis. Althoughconservative treatment was considered the gold standard previously, there is an increased tendency toward internal fixation with excellent results.This study concludes that displaced intra-articular fractures of calcaneum give good results by open reduction and internal fixation with locking plates.
FOURNIERS GANGRENE OF THE EXTERNAL GENITALIA: PLASTIC RECONSTRUCTION BY THIN SKIN GRAFT
Authors:   Department of Plastic, Reconstructive, Aesthetic and Burn Surgery, UHC Mohammed VI, Marrakech, Morocco., Elgueouatri M. , Elatiqi O. ,   Department of Plastic, Reconstructive, Aesthetic and Burn Surgery, UHC Mohammed VI, Marrakech, Morocco., Amrani M.D. ,   Department of Plastic, Reconstructive, Aesthetic and Burn Surgery, UHC Mohammed VI, Marrakech, Morocco., Benchamkha Y. ,   Department of Plastic, Reconstructive, Aesthetic and Burn Surgery, UHC Mohammed VI, Marrakech, Morocco.
Published: June 2022

To present our contribution to surgical reconstruction ofFourniers Gangrene of the External Genitalia (FG-EG), depending on the lesions.This is a retrospective study of 32 patients initially treated in the urology department of the Mohammed VI University Hospital of Marrakech, between January 2016 and December 2021. The mean age of the patients was 51. (30-72) years. All were men. All of them presented an infectious picture, thirteen of them were treated by hydroelectrolytic resuscitation and tri-antibiotic therapy. The skin lesions observed concerned the external genitalia (EG) in 08 cases (25%), then the scrotum and perineum in 24 cases (75%). All skin lesions were stripped, followed by local dressings. Thus, 28 patients (87.5%) had healed after a thin skin graft taken from the inner thigh, and 04 patients (12.5%) presented with a graft release and were then led in directed healing. Gangrene of the external genitalia FG-EG is a serious condition, which realizes, on the one hand, a toxi-infection treated by resuscitation and tri-antibiotic therapy, on the other hand, more or less extensive skin lesions requiring debridement, stripping, dressing, and then a plastic surgical reconstruction that restores an adequate penoscrotal environment that does not compromise the quality of sexual intercourse as well as the reproductive function of the testicles, especially in the young subject.
Visual Variety on the Change of Bridal Ornamental Kebaya Clothes for Generation Z in Sumenep, Madura
Authors: Soelistyowati Soelistyowati
Published: June 2022

The research discussed one of the problems with Indonesian cultural heritage in this digital world like nowadays. It was the form of decoration on wedding dresses in the Sumenep-Madura area, which was rarely seen in Indonesia, especially wedding dresses. They made some modifications to the traditional Madura wedding dress to look more modern. In this digital world where people could easily access everything, generation Z preferred cultural products from abroad rather than local culture. The research applied a qualitative method with descriptive analysis of document analysis and library sources with Java-Madura boundaries. The interviewes were conducted with cultural experts, young women, especially those who were about to get married, and creative industry players of bridal kebaya. The aim of the research was to determine the interest of young people in the decoration of wedding dresses. The research used the theory of triadic interplay concept analysis of forms, visuals and characters, and ornamentation as a visual object of tradition that was expected to be able to transform not only as an object of decoration but also as an object of education that gave value and meaning to its users. The research finds it important to study the changes in decoration to be maintained by revitalizing it without leaving the old form based on design work that can be applied through creation. By using quantitative methods through experiments with detachable techniques, fashion design concepts with meaning values can be conveyed in each form, motif, and ornament. So that the younger generation accepts and likes changes in decoration with modern forms that can practically be mixed and matched.
Horses’ perception of a threat posed by sounds of different origin
Authors: JANICKA WIKTORIA , WILK IZABELA , RYŻAK MAGDALENA
Published: June 2022

The aim of the study was to assess the behavioural reaction and emotional arousal of warmblood horses in response to sounds of different origin, and to classify those sounds into neutral ones, those causing a behavioural change and those causing a behavioural and physiological stress response. We tested the hypothesis that the perception of a sound as neutral or potentially threatening does not simply depend on the sound origin per se, but rather on the context in which the sound occurrs (predictability), additionally enhanced by the novelty effect. Recordings of 40 sounds, known (KS) and unknown (US), from four groups: anthropogenic (AS), neutral animal (NAS), predator (PS), and inanimate environment sounds (IES), were played to 20 warmblood horses remaining in their familiar paddock. The duration, frequency or occurrence of certain behaviours (e.g. walking, feeding, standing alert, stopping current activity), the heart rate (HR) and heart rate variability (HRV) were measured. The horses’ reactions were rather weak and short-term. Most of the sounds resulted in distraction (increase in alertness). The horses ate less, walked and stood alert longer, and had a higher HR after certain sounds were played. The strongest stress response (physiological and behavioural) to NAS, mostly US, was observed. PS caused behavioural disturbance, but no cardiac activity changes. The weakest responses were observed for AS and IES. Modern, stable-kept horses remain vigilant to auditory stimuli in their environment and differentiate their responses to different sounds. The perception of a threat posed by sounds depends on their unpredictability and novelty.
Antioxidant activity of doum fruit extract (hyphaene thebaica) as an alternative to antidiabetic drinks
Authors: Damayanti Ida Ayu Manik , Antari Ni Wayan Sukma , Wulansari Nadya Treesna
Published: June 2022

Diabetes Mellitus (DM) is a public health problem that occurs not only in Indonesia but throughout the world. The use of insulin and oral antidiabetic drugs is often burdensome to patients because of the high cost and side effects. The balance of free radicals in the body is formed because there are antioxidants. Antioxidants function as the body's defense mechanism against free radicals. Doum fruit or Doum fruit is an alternative fruit that is rarely known to have various kinds of active compounds such as polyphenolic flavonoids. There has not been much research on Doum fruit or doum fruit, it is deemed necessary to do research on the antioxidant test of Doum fruit extract (Hyphaene thebaica) as an alternative to antidiabetic drinks. The analysis was carried out by testing the water content and the antioxidant activity test (% inhibition) using the DPPH method. The results showed that the IC50 value in boiled water was 74,098 ppm, and Doum immersion water was 78,654 including strong antioxidant activity.
FASCÍCULO COMPLEMENTARIO XXII: REVISIÓN Y ACTUALIZACIÓN DEL INVENTARIO DE LA FLORA ESPONTÁNEA DEL JARDÍN BOTÁNICO “EL CHARCO DEL INGENIO”, SAN MIGUEL DE ALLENDE, GUANAJUATO (MÉXICO)
Authors:   Independeinte, Meagher Walter L.
Published: June 2022

El presente estudio consiste en una revisión del inventario florístico y en el análisis de algunos aspectos de la vegetación del Jardín Botánico “El Charco del Ingenio” (en lo sucesivo “El Charco”), ubicado en San Miguel de Allende, Guanajuato, México (en lo sucesivo “San Miguel”). La investigación original fue llevada a cabo entre 1991 y 1993 (Meagher, 1994, en lo sucesivo “la edición previa (1994)”); la revisión del texto original se realizó durante 2004 y 2005. Desde 1993, El Charco ha ampliado su superficie a un área contigua semisilvestre, conocida como Parque Landeta; la lista de plantas resultado de su estudio está incluida en la presente revisión. Un inventario florístico, aun tan reducido como el de El Charco, representa una ventana de la naturaleza en Guanajuato, y puede servir como modelo comparativo en relación con otros listados de la región. Y tal vez lo más importante, puede ser una referencia para una futura evaluación del propio proyecto, como área protegida.
FASCÍCULO COMPLEMENTARIO XXIII: DIVERSIDAD DEL GÉNERO IPOMOEA L. (CONVOLVULACEAE) EN EL ESTADO DE MICHOACÁN, MÉXICO
Authors:   Instituto de Ecología, A.C., Centro regional del Bajío, Carranza González Eleazar
Published: June 2022

La presente contribución pretende dar a conocer la diversidad del género Ipomoea en el estado de Michoacán, así como ofrecer una clave dicotómica para la determinación de sus especies y variedades e incluir imágenes que ilustren su distinción y a la vez apoyen el proceso de su identificación. El género Ipomoea de la familia Convolvulaceae agrupa representantes de los más conspicuos y llamativos en la flora mexicana, principalmente durante los meses lluviosos del año, pero sin faltar tampoco durante la época seca. Estas plantas muestran una gran diversificación en su morfología, por lo que es común encontrar desde pequeñas herbáceas, hasta grandes lianas, arbustos y algunos árboles; se observan tallos volubles, trepadores o erguidos ofreciendo diferentes portes. Las flores exhiben una amplia gama de colores, que varían desde el blanco hasta los matizados de azul, rojo o amarillo en diferentes tonalidades; su tamaño y forma también son diversos. Las hojas pueden ser simples o compuestas (pinnati- o palmatisectas) y en cuanto a su figura generalmente varían de lanceoladas a ovadas u orbiculares, enteras a 3 a 7-lobadas, con el ápice agudo, acuminado, atenuado o solamente mucronado y la base truncada, cordada, hastada, auriculada, cuneada o redondeada. Respecto al indumento de las diferentes partes de las plantas existe también bastante discrepancia, así con frecuencia se observan estructuras glabras o con distintos tipos e intensidades de pubescencia, siendo algunos de los más comunes el hirsuto, tomentoso, híspido y lanoso. En cuanto a las semillas, éstas pueden ser glabras o en muchos de los casos presentar diversas clases de pelos de tamaño variable, caracteres diagnósticos principalmente de algunos grupos infragenéricos. Este género es uno de los mejor representados en la flora de la República Mexicana y la mayor diversificación se ubica en las zonas tropicales, principalmente en hábitats modificados por la mano del hombre (McDonald, 1991; Rzedowski, 1978; Carranza, 2001). En el territorio del estado de Michoacán se encuentran abundantes lugares adecuados para el establecimiento de estas plantas (Carranza, 2005b), propiciados tanto por su amplia variación ecológica, como por el alto grado de alteración en muchos de los ambientes de las regiones cálidas del mismo. Son escasos los trabajos que agrupan o mencionan las especies de este género en el estado, sin embargo en el listado florístico para Michoacán de Rodríguez y Espinosa (1996) se enumeran 48 (de las cuales se aceptan aquí 43 nombres válidos). En 2005, Carranza define un total de 66 taxa, sin proporcionar sus nombres. En varios estudios regionales en los que se describe la flora y/o la vegetación de localidades particulares se hace mención de la presencia de algunas especies de Ipomoea.
Влияние термомагнитных обработок на доменную структуру аморфных пленок типа файнмет
Authors: Иванов В.Е. , Лепаловский В.Н.
Published: June 2022

Thermomagnetic processing of films of the finemet type with an easy magnetization axis in the plane under the action of a constant and rotating magnetic field was carried out in order to obtain an isotropic state. After heat treatment in a constant field, the easy magnetization axis was reoriented along the line of action of the field, as a result of which the domain walls were oriented along the new axis. After thermomagnetic treatment in a rotating field regions with different anisotropy patterns, including isotropic regions, were revealed.
Feedback on Trunk Movements From an Electronic Game to Improve Postural Balance in People With Nonspecific Low Back Pain: Pilot Randomized Controlled Trial
Authors: Meinke Anita , Peters Rick , Knols Ruud H , Swanenburg Jaap , Karlen Walter
Published: June 2022

Background

Postural balance is compromised in people with low back pain, possibly by changes in motor control of the trunk. Augmenting exercising interventions with sensor-based feedback on trunk posture and movements might improve postural balance in people with low back pain.

Objective

We hypothesized that exercising with feedback on trunk movements reduces sway in anterior-posterior direction during quiet standing in people with low back pain. Secondary outcomes were lumbar spine and hip movement assessed during box lift and waiter bow tasks, as well as participant-reported outcomes. Adherence to the exercising intervention was also examined.

Methods

A randomized controlled trial was conducted with the intervention group receiving unsupervised home exercises with visual feedback using the Valedo Home, an exergame based on 2 inertial measurement units. The control group received no intervention. Outcomes were recorded by blinded staff during 4 visits (T1-T4) at University Hospital Zurich. The intervention group performed 9 sessions of 20 minutes in the 3 weeks between T2 and T3 and were instructed to exercise at their own convenience between T3 and T4. Postural balance was assessed on a force platform. Lumbar spine and hip angles were obtained from 3 inertial measurement units. The assessments included pain intensity, disability, quality of life, and fear of movement questionnaires.

Results

A total of 32 participants with nonspecific low back pain completed the first assessment T1, and 27 (84%) participants were randomized at T2 (n=14, 52% control and n=13, 48% intervention). Intention-to-treat analysis revealed no significant difference in change in anterior-posterior sway direction during the intervention period with a specified schedule (T2-T3) between the groups (W=99; P=.36; r=0.07). None of the outcomes showed significant change in accordance with our hypotheses. The intervention group completed a median of 61% (55/90; range 2%-99%) of the exercises in the predefined training program. Adherence was higher in the first intervention period with a specified schedule.

Conclusions

The intervention had no significant effect on postural balance or other outcomes, but the wide range of adherence and a limited sample size challenged the robustness of these conclusions. Future work should increase focus on improving adherence to digital interventions.

Trial Registration

ClinicalTrials.gov NCT04364243; https://clinicaltrials.gov/ct2/show/NCT04364243

International Registered Report Identifier (IRRID)

RR2-10.2196/26982
Electronic Health Record–Based Recruitment and Retention and Mobile Health App Usage: Multisite Cohort Study
Authors: Coughlin Janelle W , Martin Lindsay M , Zhao Di , Goheer Attia , Woolf Thomas B , Holzhauer Katherine , Lehmann Harold P , Lent Michelle R , McTigue Kathleen M , Clark Jeanne M , Bennett Wendy L
Published: June 2022

Background

To address the obesity epidemic, there is a need for novel paradigms, including those that address the timing of eating and sleep in relation to circadian rhythms. Electronic health records (EHRs) are an efficient way to identify potentially eligible participants for health research studies. Mobile health (mHealth) apps offer available and convenient data collection of health behaviors, such as timing of eating and sleep.

Objective

The aim of this descriptive analysis was to report on recruitment, retention, and app use from a 6-month cohort study using a mobile app called Daily24.

Methods

Using an EHR query, adult patients from three health care systems in the PaTH clinical research network were identified as potentially eligible, invited electronically to participate, and instructed to download and use the Daily24 mobile app, which focuses on eating and sleep timing. Online surveys were completed at baseline and 4 months. We described app use and identified predictors of app use, defined as 1 or more days of use, versus nonuse and usage categories (ie, immediate, consistent, and sustained) using multivariate regression analyses.

Results

Of 70,661 patients who were sent research invitations, 1021 (1.44%) completed electronic consent forms and online baseline surveys; 4 withdrew, leaving a total of 1017 participants in the analytic sample. A total of 53.79% (n=547) of the participants were app users and, of those, 75.3% (n=412), 50.1% (n=274), and 25.4% (n=139) were immediate, consistent, and sustained users, respectively. Median app use was 28 (IQR 7-75) days over 6 months. Younger age, White race, higher educational level, higher income, having no children younger than 18 years, and having used 1 to 5 health apps significantly predicted app use (vs nonuse) in adjusted models. Older age and lower BMI predicted early, consistent, and sustained use. About half (532/1017, 52.31%) of the participants completed the 4-month online surveys. A total of 33.5% (183/547), 29.3% (157/536), and 27.1% (143/527) of app users were still using the app for at least 2 days per month during months 4, 5, and 6 of the study, respectively.

Conclusions

EHR recruitment offers an efficient (ie, high reach, low touch, and minimal participant burden) approach to recruiting participants from health care settings into mHealth research. Efforts to recruit and retain less engaged subgroups are needed to collect more generalizable data. Additionally, future app iterations should include more evidence-based features to increase participant use.
A Group Videoconferencing Intervention (C@nnected) to Improve Maternal Sensitivity: Protocol for a Randomized Feasibility Trial
Authors: Binda Victoria , Olhaberry Marcia , Castañon Carla , Abarca Constanza , Caamaño Catalina
Published: June 2022

Background

Early childhood development is highly dependent on the sensitive care provided by caregivers, and interventions focused on supporting parents to improve their sensitivity have shown to be effective. The COVID-19 pandemic has had a significant impact on mental health, with pregnant women and mothers of infants being an especially vulnerable group and maternal sensitivity particularly affected. However, access to face-to-face interventions is restricted; thus, it is important to have remote interventions to support this group of mothers.

Objective

The objective of this study is to evaluate the feasibility and acceptability of C@nnected, a group videoconferencing intervention to improve maternal sensitivity aimed at mother-infant dyads attending primary health care centers in vulnerable areas of Santiago, Chile.

Methods

This is a randomized feasibility single-masked (outcome assessor) study with a qualitative component. It will involve a block randomization procedure to generate a 3:2 allocation ratio (with more people allocated to the intervention arm). The intervention consists of 4 group videoconferencing sessions adapted from a face-to-face intervention with proven effectiveness. The control group will receive treatment as usual, along with educational brochures. The feasibility and acceptability of this study will be quantitatively and qualitatively assessed. Changes in clinical outcomes relating to maternal sensitivity, depressive symptoms, postpartum maternal attachment, and infant socioemotional development will also be evaluated.

Results

We finished adapting the face-to-face intervention to the videoconferencing format in July 2021. The study began recruitment in August 2021, and enrollment is expected to end in August 2022, with final study results expected in December 2022.

Conclusions

This study will contribute evidence for the use of eHealth interventions to promote maternal sensitivity. It will also inform the design and implementation of a future randomized clinical trial.

Trial Registration

ClinicalTrials.gov NCT04904861; https://clinicaltrials.gov/ct2/show/NCT04904861

International Registered Report Identifier (IRRID)

DERR1-10.2196/35881
Feedback on Trunk Movements From an Electronic Game to Improve Postural Balance in People With Nonspecific Low Back Pain: Pilot Randomized Controlled Trial (Preprint)
Authors: Meinke Anita , Peters Rick , Knols Ruud H , Swanenburg Jaap , Karlen Walter
Published: June 2022

BACKGROUND

Postural balance is compromised in people with low back pain, possibly by changes in motor control of the trunk. Augmenting exercising interventions with sensor-based feedback on trunk posture and movements might improve postural balance in people with low back pain.

OBJECTIVE

We hypothesized that exercising with feedback on trunk movements reduces sway in anterior-posterior direction during quiet standing in people with low back pain. Secondary outcomes were lumbar spine and hip movement assessed during box lift and waiter bow tasks, as well as participant-reported outcomes. Adherence to the exercising intervention was also examined.

METHODS

A randomized controlled trial was conducted with the intervention group receiving unsupervised home exercises with visual feedback using the Valedo Home, an exergame based on 2 inertial measurement units. The control group received no intervention. Outcomes were recorded by blinded staff during 4 visits (T1-T4) at University Hospital Zurich. The intervention group performed 9 sessions of 20 minutes in the 3 weeks between T2 and T3 and were instructed to exercise at their own convenience between T3 and T4. Postural balance was assessed on a force platform. Lumbar spine and hip angles were obtained from 3 inertial measurement units. The assessments included pain intensity, disability, quality of life, and fear of movement questionnaires.

RESULTS

A total of 32 participants with nonspecific low back pain completed the first assessment T1, and 27 (84%) participants were randomized at T2 (n=14, 52% control and n=13, 48% intervention). Intention-to-treat analysis revealed no significant difference in change in anterior-posterior sway direction during the intervention period with a specified schedule (T2-T3) between the groups (W=99; P=.36; r=0.07). None of the outcomes showed significant change in accordance with our hypotheses. The intervention group completed a median of 61% (55/90; range 2%-99%) of the exercises in the predefined training program. Adherence was higher in the first intervention period with a specified schedule.

CONCLUSIONS

The intervention had no significant effect on postural balance or other outcomes, but the wide range of adherence and a limited sample size challenged the robustness of these conclusions. Future work should increase focus on improving adherence to digital interventions.

CLINICALTRIAL

ClinicalTrials.gov NCT04364243; https://clinicaltrials.gov/ct2/show/NCT04364243

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/26982
The Cancer Research Database (CRDB): Integrated Platform to Gain Statistical Insight Into the Correlation Between Cancer and COVID-19 (Preprint)
Authors: Ullah Shahid , Ullah Farhan , Rahman Wajeeha , Karras Dimitrios A , Ullah Anees , Ahmad Gulzar , Ijaz Muhammad , Gao Tianshun
Published: June 2022

BACKGROUND

The advancement of cancer research has been facilitated through freely available cancer literature, databases, and tools. The age of genomics and big data has given rise to the need for cooperation and data sharing in order to make efficient use of this new information in the COVID-19 pandemic. Although there are many databases for cancer research, their access is not easy owing to different ways of processing and managing the data. There is an absence of a unified platform to manage all of them in a transparent and more comprehensible way.

OBJECTIVE

In this study, an improved integrated cancer research database and platform is provided to facilitate a deeper statistical insight into the correlation between cancer and the COVID-19 pandemic, unifying the collection of almost all previous published cancer databases and defining a model web database for cancer research, and scoring databases on the basis of the variety types of cancer, sample size, completeness of omics results, and user interface.

METHODS

Databases examined and integrated include the Data Portal database, Genomic database, Proteomic database, Expression database, Gene database, and Mutation database; and it is expected that this launch will sort, save, advance the understanding and encourage the use of these resources in the cancer research environment.

RESULTS

To make it easy to search valuable information, 85 cancer databases are provided in the form of a table, and a database of databases named the Cancer Research Database (CRDB) has been built and presented herein. Furthermore, the CRDB has been herein equipped with unique navigation tools in order to be explored by three methods; that is, any single database can be browsed by typing the name in the given search bar, while all categories can be browsed by clicking on the name of the category or image expression icon, thus serving as a facility that could provide all the category databases on a single click.

CONCLUSIONS

The computational platform (PHP, HTML, CSS, and MySQL) used to build CRDB for the cancer scientific community can be freely investigated and browsed on the internet and is planned to be updated in a timely manner. In addition, based on the proposed platform, the status and diagnoses statistics of cancer during the COVID-19 pandemic have been thoroughly investigated herein using CRDB, thus providing an easy-to-manage, understandable framework that mines knowledge for future researchers.
Time-Varying Associations Between Device-Based and Ecological Momentary Assessment–Reported Sedentary Behaviors and the Concurrent Affective States Among Adolescents: Proof-of-Concept Study (Preprint)
Authors: Zink Jennifer , Yang Chih-Hsiang , Alves Jasmin M , McAlister Kelsey L , Huh Jimi , Pentz Mary Ann , Page Kathleen A , Dunton Genevieve F , Belcher Britni R
Published: June 2022

BACKGROUND

Previous studies on affective state–sedentary behavior (SB) associations have not accounted for their potentially time-varying nature and have used inconsistent SB measurement modalities. We investigated whether the strength of the associations between affective states and SB varied as a function of the time of day and by SB measurement modality (device-measured SB vs ecological momentary assessment–reported screen-based SB) in youth.

OBJECTIVE

This study aimed to establish a proof of concept that SB–affective state associations may not be static during the day. In addition, we aimed to inform the methodology of future work, which may need to model associations as functions of the time of day and carefully consider how SB is operationalized or measured.

METHODS

A total of 15 adolescents (age: mean 13.07, SD 1.03 years; 10/15, 67% female; 6/15, 40% Hispanic; 10/15, 67% healthy weight) wore thigh-mounted activPAL accelerometers and simultaneously reported their screen-based SBs and concurrent positive and negative affective states via ecological momentary assessment for 7 to 14 days (N=636 occasions). Time-varying effect models (varying slopes) examined how each measure of SB was associated with concurrent affective states from 7 AM to 8 PM.

RESULTS

Time-varying effect model plots revealed that these associations varied in strength throughout the day. Specifically, device-based SB was related to greater concurrent negative affect only after approximately 5 PM and was unrelated to concurrent positive affect. Screen-based SB was related to greater concurrent negative affect only from 7 AM to approximately 9 AM. This was also related to greater concurrent positive affect from 7 AM to approximately 9:30 AM and from approximately 3 PM to approximately 7 PM.

CONCLUSIONS

We provide preliminary evidence to suggest that future confirmatory studies investigating the SB–affective state relationship should consider the time-varying nature of these associations and SB measurement modality. There may be critical time windows when specific types of SBs co-occur with affect, suggesting that interventions may need tailoring to the time of day and type of SB if future studies using similar methodologies can replicate our findings.

CLINICALTRIAL
The Factors Associated With Confidence in Using the Internet to Access Health Information: Cross-sectional Data Analysis (Preprint)
Authors: Van Heel Kasi Lou , Nelson Anna , Handysides Daniel , Shah Huma
Published: June 2022

BACKGROUND

Confidence in health information access is a measure of the perceived ability to obtain health information. One’s beliefs or perceived ability to access health information is particularly important in understanding trends in health care access. Previous literature has found that access to health information is lowest among society’s most vulnerable population groups. These groups include older, less educated, and low-income populations. While health confidence has previously been used as a scale to measure health outcomes, additional research is needed describing the demographic factors associated with users’ confidence in health information access. This may be a key component of health information seeking that affects beneficial health outcomes such as prevention and treatment.

OBJECTIVE

This study examines the demographic factors associated with the levels of confidence in using the internet to access health information for adults 18 years and older in the United States.

METHODS

Using a cross-sectional design, secondary data from the Health Information National Trends Survey (HINTS) 5, Cycle 3 (2019) were analyzed (N=5374). An ordinal regression stratified by internet use was used to determine the association between demographic characteristics and level of confidence in health information access.

RESULTS

When the internet is the primary source for health information, high school graduates (adjusted odds ratio [AOR] 0.58, 95% CI 0.37-0.89) compared to those with a college degree or more had significantly lower odds of being confident in obtaining health information. In addition, non-Hispanic Asian participants (AOR 0.44, 95% CI 0.24-0.82) compared to non-Hispanic White participants, male participants (AOR 0.72, 95% CI 0.54-0.97) compared to female participants, and those who made between US $20,000-$35,000 annually (AOR 0.55, 95% CI 0.31-0.98) compared to those who made US $75,000 or more annually had significantly lower odds of being confident in obtaining health information via the internet. Moreover, when the internet is the primary source for health information, those with health insurance had significantly higher odds of being confident in obtaining health information (AOR 2.91, 95% CI 1.58-5.34) compared to those who do not have health insurance. Lastly, a significant association was observed between confidence in health information access and primary health information source and frequency of visiting a health care provider.

CONCLUSIONS

Confidence in accessing health information can differ by individual demographics. Accessing health-related information from the internet has become increasingly more common and can provide insight into health information-seeking behaviors. Further exploration of these factors can inform the science of health education by providing deeper insight into improving access to health information for vulnerable populations.
A comprehensive review of mobile applications in COVID-19 detection and diagnosis: An efficient tool to control the pandemic (Preprint)
Authors: Ghaderzadeh Mustafa , Taami Tania , Hosseini Azamossadat , Garavand 4th Ali , Rahmani َAmir Masoud
Published: June 2022

BACKGROUND

Today, mobile applications are integral to human progress, and COVID-19 control is no exception. Numerous studies have focused on detecting and diagnosing this disease using mobile technology and applications. Still, no comprehensive research has reviewed these studies regarding COVID-19 outbreak prevention

OBJECTIVE

The current study comprehensively addressed the various uses of mobile applications for COVID-19 detection and diagnosis

METHODS

A search of five major research databases (ScienceDirect, Scopus, PubMed, Web of Science, IEEE) found 535 studies, among which 42 related to the diagnosis and detection of patients suspected of having COVID-19.

RESULTS

Examining the content of these studies revealed that mobile applications can be classified into five categories: contact tracing, data gathering, data visualization, artificial intelligence-based methods, rule- and guideline-based methods, and data transformation. Mobile applications have been utilized to detect patients with COVID-19 using diverse clinical, geographic, demographic, radiological, serological, and laboratory data. The majority of studies focused on applying artificial intelligence (AI) techniques to detect individuals suspected of having COVID-19. Also, symptoms, cough sounds, and radiology images were used more frequently than other data types.

CONCLUSIONS

In the future, mobile applications, along with the Internet of Things (IoT), cloud storage, 5G, and cloud computing technologies, can play a major role as a robust tool in data gathering, epidemic health data analysis, and early diagnosis of suspected cases.
Social Distancing Detection Using Computer Vision
Authors: Narayan Hrishikesh , Pawar Ayush , Kumar Ankit , Narayan Avinash , Waware Pooja
Published: June 2022

Abstract: SARS-CoV-19 is one of the deadliest pandemics the world has witnessed, taking around 6 crore lives till now across worldwide and about 6 lakhs in India. To limit its spread numerous countries have issued many safety measures. Due to the absence of the vaccine against the covid-19 the world has suffered a lot. Though scientists have developed several vaccines then also the pandemic is still out of control so therefore the only feasible option available to us is social distancing. We are implementing a Deep-learning based solution proposed for the above-stated problem. The distance between people can be estimated and the pair of people in the display will be indicated with red or green bounding boxes over it. The video frame from the camera was used as input, and the open-source object detection pre-trained model based on the YOLOv4 / YOLOv5 algorithm was employed for pedestrian detection. Later, the video frame was transformed into a top-down view for distance measurement from the 2D plane. The connection of CCTV cameras in public areas, public transportation, and hospitals is useful for gathering information. The proposed method was validated on a pre-recorded video of pedestrians walking on the street. Keywords: Deep learning, YOLOv4 / YOLOv5 algorithms, Social Distancing, Covid - 19
External Locus of Control and Elementary Teachers' Subjective Wellbeing: Self-efficacy As a Mediator
Authors: Yin Weiwei
Published: June 2022

In this study I explored the relationships among the locus of control, self-efficacy, and subjective well-being (SWB) of elementary school teachers in China, with a focus on the mediating effect of self-efficacy in the relationship between external locus of control and SWB. A survey
was conducted with 305 elementary school teachers using the Adult Nowicki-Strickland Internal-External Locus of Control Scale, the General Self-Efficacy Scale, and SWB measurements. External locus of control was found to be negatively correlated with SWB, and selfefficacy was positively correlated
with SWB. Structural equation modeling analysis showed that self-efficacy partially mediated the effect of external locus of control on SWB, with the indirect effect accounting for 36.34% of the total explained variance. Promoting a sense of control and self-efficacy may be effective in improving
elementary school teachers' SWB.
Pasado, presente y futuro del clima en el Parque Nacional Chirripó, Costa Rica
Authors: Quesada Román Adolfo
Published: June 2022

Introducción: El Parque Nacional Chirripó ha tenido cambios climáticos definidos por su ubicación y por características geológicas, geomorfológicas, ecológicas y edáficas. Objetivo: Identificar los factores que han modulado el clima en las altas cimas de Costa Rica. Métodos: Una revisión bibliográfica en Google Académico en setiembre de 2021. Resultados: El tema ha sido estudiado por la geología, geomorfología, palinología y geografía, reconstruyendo el clima durante el Último Máximo Glaciar, aproximadamente hace unos 20.000 años en el Parque Nacional Chirripó. Conocemos las condiciones climatológicas que normalmente han predominado en el parque durante las últimas décadas y cómo El Niño–Oscilación del Sur modela el clima actual. También hay modelos para proyectar las condiciones climáticas durante todo el siglo XXI en esta área protegida. Conclusión: Hay suficientes estudios del clima del parque para promocionar su geoconservación y dar mejores guías para su manejo.
Effects of surgeon volume and hospital volume on clinical outcomes of breast cancer patients
Authors: Pavlushenko Mariia , Liubota Roman , Vereshchako Roman , Anikusko Nikolay , Liubota Irina
Published: June 2022

Cancer presents significant hurdle in the goal to increase the life expectancy of the world population. In 2020 breast cancer has become the leading cause of global cancer in the female population, ahead of lung cancer. Over the past half century, approach to the treatment of breast cancer has changed dramatically that led to improvement of survival rates and quality of life of patients. In particular, the changes affected the surgical treatment of breast cancer. The modern tactics of treating breast cancer patients has become more complex and requires a multidisciplinary approach led by an oncological surgeon. It requires the availability of specialized material and equipment in medical institutions and practical skills of surgeons that provide medical care to breast cancer patients. However, breast cancer patients may not receive the entire range of modern treatment options, due to limited capabilities of medical institution and/or surgeon that leads to deterioration in duration and quality of life of patients. The quality of medical care for breast cancer patients is directly proportional to the number of cases performed annually at a medical institution (hospital volume) or by a surgeon (surgeon volume). The results of this study can serve as a basis for further investigations of the relationship between the surgeon and hospital volume and other factors affecting the quality and diversity of medical care for breast cancer patients.