bluuebunny/crossref_metadata_2025 huggingface dataset:
Synergistic Therapeutic Effects of D-Mannitol–Cerium–Quercetin (Rutin) Coordination Polymer Nanoparticles on Acute Lung Injury
Authors: Zhang Yusheng , Wang Hong , Yang Ruiying , Zhang Ying , Chen Yao , Jiang Cuiping , Li Xianyu
Published: June 2024

Acute lung injury (ALI) remains a significant global health issue, necessitating novel therapeutic interventions. In our latest study, we pioneered the use of D-mannitol–cerium–quercetin/rutin coordination polymer nanoparticles (MCQ/R NPs) as a potential treatment for ALI. The MCQ/R NPs, which integrate rutin and quercetin for their therapeutic potential and D-mannitol for its pulmonary targeting, displayed exceptional efficacy. By utilizing cerium ions for optimal nanoparticle assembly, the MCQ/R NPs demonstrated an average size of less than 160 nm. Impressively, these nanoparticles outperformed conventional treatments in both antioxidative capabilities and biocompatibility. Moreover, our in vivo studies on LPS-induced ALI mice showed a significant reduction in lung tissue inflammation. This groundbreaking research presents MCQ/R NPs as a promising new approach in ALI therapeutics.
Chemical and Bioactive Evaluation of Essential Oils from Edible and Aromatic Mediterranean Lamiaceae Plants
Authors: Spréa Rafael M. , Caleja Cristina , Finimundy Tiane C. , Calhelha Ricardo C. , Pires Tânia C. S. P. , Amaral Joana S. , Prieto Miguel A. , Ferreira Isabel C. F. R. , Pereira Eliana , Barros Lillian
Published: June 2024

The Lamiaceae family, which includes several well-known aromatic plants, is scientifically relevant due to its essential oils (EOs). In this work, four EOs from Mediterranean species, namely Origanum vulgare L., Rosmarinus officinalis L., Salvia officinalis L., and Thymus vulgaris L., were evaluated for their volatile profiles and the biological activity in vitro to assess their potential use in the food and cosmetic sector. GC/MS analysis revealed dominant compounds, such as carvacrol, thymol, and eucalyptol. Regarding biological action, the samples exhibited antioxidant, cytotoxic, anti-inflammatory, antimicrobial, and antifungal activities, with O. vulgare and T. officinalis standing out. T. vulgaris showed the lowest EC50 in the reducing power assay, and O. vulgare had the lowest EC50 in the DPPH assay. Most EOs also displayed excellent anti-inflammatory responses and antifungal properties, with O. vulgare and T. vulgaris also demonstrating antibacterial activity. All EOs from Mediterranean species showed cytotoxicity against tumoral cell lines. Overall, the selected EOs stood out for their interesting bioactivities, with the obtained results underscoring their potential as natural preservatives and bioactive agents in various industrial applications, including food, pharmaceuticals, and cosmetics.
Simple Determination of Affinity Constants of Antibodies by Competitive Immunoassays
Authors: Fischer Janina , Kaufmann Jan Ole , Weller Michael G.
Published: June 2024

The affinity constant, also known as the equilibrium constant, binding constant, equilibrium association constant, or the reciprocal value, the equilibrium dissociation constant (Kd), can be considered as one of the most important characteristics for any antibody–antigen pair. Many methods based on different technologies have been proposed and used to determine this value. However, since a very large number of publications and commercial datasheets do not include this information, significant obstacles in performing such measurements seem to exist. In other cases where such data are reported, the results have often proved to be unreliable. This situation may indicate that most of the technologies available today require a high level of expertise and effort that does not seem to be available in many laboratories. In this paper, we present a simple approach based on standard immunoassay technology that is easy and quick to perform. It relies on the effect that the molar IC50 approaches the Kd value in the case of infinitely small concentrations of the reagent concentrations. A two-dimensional dilution of the reagents leads to an asymptotic convergence to Kd. The approach has some similarity to the well-known checkerboard titration used for the optimization of immunoassays. A well-known antibody against the FLAG peptide, clone M2, was used as a model system and the results were compared with other methods. This approach could be used in any case where a competitive assay is available or can be developed. The determination of an affinity constant should belong to the crucial parameters in any quality control of antibody-related products and assays and should be mandatory in papers using immunochemical protocols.
A Tunable Graphene Superlattice with Deformable Periodical Nano-Gating
Authors: Wei Binbin , Ying Haosong , Chen Junrong , Zang Qing , Dong Jiduo , Zhang Hao , Liu Yang , Liu Chunheng
Published: June 2024

Graphene superlattices have simple and controllable electronic band structures, which can also be electrostatically tuned. They have been widely studied for band engineering and strong correlated physics, and have led to the discovery of a variety of exciting phenomena. To experimentally study the physics of graphene superlattices in a systematic way, it is desirable to control the structure parameters, which barely exist at the moment, onsite. Here, a tunable superlattice with graphene and a deformable gating structure is demonstrated. The period and duty cycle of the nano-gating, and furthermore of the superlattice potential, can be tuned through altering the shape of the gating structure with piezo-actuators, offering a tunable band structure. The tuning of the electronic band structures of both a two-dimensional and a one-dimensional superlattice is demonstrated with numerical simulations, offering a new approach for tunable electronic and photonic devices.
The miRNA Contribution in Adipocyte Maturation
Authors: Giammona Alessandro , Di Franco Simone , Lo Dico Alessia , Stassi Giorgio
Published: June 2024

Mesenchymal stem cells, due to their multipotent ability, are considered one of the best candidates to be used in regenerative medicine. To date, the most used source is represented by the bone marrow, despite the limited number of cells and the painful/invasive procedure for collection. Therefore, the scientific community has investigated many alternative sources for the collection of mesenchymal stem cells, with the adipose tissue representing the best option, given the abundance of mesenchymal stem cells and the easy access. Although adipose mesenchymal stem cells have recently been investigated for their multipotency, the molecular mechanisms underlying their adipogenic potential are still unclear. In this scenario, this communication is aimed at defining the role of miRNAs in adipogenic potential of adipose-derived mesenchymal stem cells via real-time PCR. Even if preliminary, our data show that cell culture conditions affect the expression of specific miRNA involved in the adipogenic potential of mesenchymal stem cells. The in vitro/in vivo validation of these results could pave the way for novel therapeutic strategies in the field of regenerative medicine. In conclusion, our research highlights how specific cell culture conditions can modulate the adipogenic potential of adipose mesenchymal stem cells through the regulation of specific miRNAs.
Study on the Imaging Interference of a Vortex-Light-Modulated Gaussian Beam
Authors: Liu Yanghe , Tang Yuanhe , Zhou Jian , Li Cunxia , Hui Ningju , Zhang Yishan , Wang Yanlong
Published: June 2024

Combined with vortex light and airglow, some different physical phenomena are presented in this paper. Based on the ground-based airglow imaging interferometer (GBAII) made by our group, a liquid crystal on silicon (LCoS) device on one arm of a wide-angle Michelson interferometer (MI) of the GBAII is replaced by the reflector mirror to become the GBAII-LCoS system. LCoS generates a vortex phase to convert a Gaussian profile airglow into a vortex light pattern. After the Gaussian profile vortex light equation is obtained by combining the Gaussian profile airglow with the Laguerre–Gauss light, three different physical phenomena are obtained: the simulated Gaussian vortex airglow beam exhibits a hollow phenomenon with the introduction of the vortex phase, and as the topological charge (TC) l increases, the hollow range also increases; after adding the vortex factor, the interference fringe intensity can be ‘broadened’ with the optical path difference (OPD) and TC l increases, which match the field broadening technology for solid wide-angle MI; the ‘Four-point algorithm’ wind measurement for the upper atmosphere based on the vortex airglow is derived, which is different from the usual expressions. Some experimental results are presented: We obtained the influence modes of vortex light interference and a polarization angle from 335° to 245°. We also obtained a series of interference images that verifies the rotation of the vortex light, onto which is loaded a set of superimposed vortex phase images with TC l = 3 into LCoS in turn, and the interference image is rotated under the condition of the polarization angle of 245°. The controlled vortex interference image for different TC and grayscale values are completed.
Endoscopic Surgical Approach for a Mesiodens in the Nasal Cavity: A Rare Phenomenon
Authors: Iacomino Enzo , Fratini Chiara , Zoccali Federica , Cambria Francesca , Laudani Matteo , Eibenstein Alberto , Barbato Christian , de Vincentiis Marco , Minni Antonio
Published: June 2024

The nasal cavity is a sporadic site for mesiodens, and if it is impacted in the lower nasal floor or localized in the nasal septum, it may cause various nasal symptoms such as nasal obstruction, recurrent rhinitis, and epistaxis. Early diagnosis is made through clinical findings and a cone-beam computed tomography (CBCT) scan, but a definite treatment plan has not yet been developed. This study aims to present a case of a mesiodens in a 27-year-old male, located in the nasal septum, an unusual and rare site, and its surgical removal using an endoscopic nasal approach with subperiosteal intranasal dissection. The result of the study appears significant because this technique led to fewer postoperative complications, and it appears to be safer and more effective than the traditional palatal or transoral approach. Moreover, the nasal endoscopic approach is more natural to the ear, nose, and throat (ENT) surgeons than the transoral approach.
Aqueous Two-Phase Flotation Combined with Gold Nanoparticle Colorimetry for Determination of Thiocyanate in Raw Milk
Authors: Jiang Bin , Yue Hongshen , Fu Xinhao , Wang Jiaming , Feng Yu , Liu Chunhong , Li Dongmei
Published: June 2024

Thiocyanates are effective in inhibiting the growth of microorganisms in raw milk to extend shelf life, but excessive addition can cause human health problems. Currently, ion chromatography and spectrophotometry are the main methods used in industry to determine SCN, but the pre-treatment process is cumbersome and time-consuming and has low sensitivity. Aqueous two-phase flotation (ATPF) technology has the advantages of simplicity, rapidity and economy. In this study, an acetonitrile/ammonium sulfate ATPF–gold nanoparticle (AuNP) colorimetric method was developed for the determination of SCN− in raw milk, and ATPF was used to separate and concentrate SCN− in raw milk to improve the detection sensitivity under convenient and economical conditions. The separation conditions were optimized by single-factor experiments and RSM, while the detection conditions, effects of CTAB concentration, pH and reaction time, were investigated. The “aggregation–anti-aggregation” mechanism of the gold-nano colorimetric method for the determination of SCN− was investigated by UV-vis absorption spectroscopy (UV-vis) and transmission electron microscopy (TEM). Under the optimal separation and detection conditions, the SCN− concentration showed a linear relationship with A630/A520 values in the concentration range of 0–2.5 mg/L with R2 of 0.9933, limit of detection (LOD) of 0.0919 mg/L, limit of quantitation (LOQ) of 0.306 mg/L, intra-day precision of 5.3% and spiked recoveries of 80.91–101.25%. In addition, the ATPF-AuNP colorimetric method demonstrated high selectivity and stability.
Green Technology for Fungal Protein Extraction—A Review
Authors: Ahmed Tanvir , Suzauddula Md , Akter Khadiza , Hossen Monir , Islam Md Nazmul
Published: June 2024

Fungal proteins are highlighted for their nutritional value and bioactive properties, making them a significant alternative to traditional protein sources. This review evaluates various green extraction technologies, including enzymatic-, ultrasound-, higher-pressure homogenization-, microwave-assisted, pulsed electric fields-, and supercritical fluid-assisted extraction, focusing on their effectiveness in disrupting fungal cell walls and preserving protein integrity. The findings indicate that these technologies could have the potential to improve protein yield and quality, addressing the challenges posed by fungal cell walls’ complex and resilient structure. The review also underscores the bioactivities of fungal proteins, including antifungal, antibacterial, antioxidant, and anticancer properties. The conclusion emphasises the need for further optimisation and scaling of these technologies, as well as exploring a wider range of fungal species to fully understand their potential as sustainable protein sources. Future research directions include refining extraction methods, integrating multiple approaches, and utilising novel green solvents to maximise efficiency and yield.
ESG and Financial Performance of China Firms: The Mediating Role of Export Share and Moderating Role of Carbon Intensity
Authors: Ding Haoming , Lee Wonhee
Published: June 2024

In recent years, ESG (environmental, social, and governance) has emerged as a critical investment concept. Its goal is to create value for both shareholders and society, encouraging companies to optimize social value. However, the exploration and research into “the proportion of firms exporting and the pathways through which the environmental, social, and governance activities of carbon-intensive firms influence firms’ financial performance” remains largely unexplored. This study establishes a research framework within this context, utilizing listed Chinese manufacturing companies as the research subjects. Taking agency theory rationale and signaling theory as the theoretical framework, this study thoroughly investigates the relationship between ESG ratings, corporate export ratios, and corporate financial performance through panel regression models using fixed-time, fixed-industry, and bi-directional fixed-effects models. The results of this study show that (1) ESG ratings have a positive impact on corporate financial performance; (2) firms’ export ratios play a mediating role in the relationship between ESG ratings and corporate financial performance; and (3) carbon-intensive firms have a positive moderating effect on the relationship between ESG ratings and corporate financial performance. Based on these findings, we propose policy recommendations at the firm and government levels to increase the importance of ESG, strengthen corporate governance, and promote continuous progress in ESG. This study provides micro evidence of the interactions between ESG ratings, export ratios, carbon-intensive firms, and firm performance to enable investors to make informed decisions.
Molecular Detection of Leishmania spp. and Blood Source of Female Sand Flies in the Parque Estadual do Rio Doce and Municipality of Timóteo, Minas Gerais, Brazil
Authors: Souza Cristian Ferreira de , Santos Carlos Alberto dos , Bevilacqua Paula Dias , Andrade Filho José Dilermando , Brazil Reginaldo Peçanha
Published: June 2024

Leishmaniasis is a group of diseases caused by protozoa of the genus Leishmania and is transmitted by the bite female sand fly. The present work is characterized as a descriptive study in two areas: a forest area located in the Parque Estadual do Rio Doce, and another urban area located in the municipality of Timóteo-MG, with the objective of identifying the presence of Leishmania spp. and the blood source of the collected female sand flies. Part of the females were obtained from the Parque Estadual do Rio Doce, and part was collected using 19 ligth traps distributed in residences of Timóteo. For molecular studies of Leishmania spp. DNA, the ITS1 gene was used, and in the search for blood source, the CytB gene was used and positive samples were sequenced. The study demonstrated that there are at least three species of Leishmania circulating in the study areas: Leishmania (Viannia) braziliensis, Leishmania (Leishmania) amazonensis, and Leishmania (V.) guyanensis. Nyssomyia whitmani was the predominant sand fly species in the urban area of Timóteo with a positive diagnosis for the presence of Leishmania braziliensis DNA. We found the presence of blood from Gallus gallus (Chicken) and Sus scrofa (Pig) in sand flies. The present study demonstrates that Leishmania braziliensis is the main agent of cutaneous leishmaniasis in the study area, with the effective participation of Nyssomyia whitmani as the vector and both Gallus gallus and Sus scrofa acting as a food source for female sand flies, and helping maintaining the sand fly life.
A Short History of the First 50 Years: From the GRB Prompt Emission and Afterglow Discoveries to the Multimessenger Era
Authors: Frontera Filippo
Published: June 2024

More than fifty years have elapsed from the first discovery of gamma-ray bursts (GRBs) with American Vela satellites, and more than twenty-five years from the discovery with the BeppoSAX satellite of the first X-ray afterglow of a GRB. Thanks to the afterglow discovery and to the possibility given to the optical and radio astronomers to discover the GRB optical counterparts, the long-time mystery about the origin of these events has been solved. Now we know that GRBs are huge explosions, mainly ultra relativistic jets, in galaxies at cosmological distances. Starting from the first GRB detection with the Vela satellites, I will review the story of these discoveries, those obtained with BeppoSAX, the contribution to GRBs by other satellites and ground experiments, among them being Venera, Compton Gamma Ray Observatory, HETE-2, Swift, Fermi, AGILE, MAGIC, H.E.S.S., which were, and some of them are still, very important for the study of GRB properties. Then, I will review the main results obtained thus far and the still open problems and prospects of GRB astronomy.
On the Effects of Non-Metricity in an Averaged Universe
Authors: Agashe Anish , Modumudi Sai Madhav
Published: June 2024

In the covariant averaging scheme of macroscopic gravity, the process of averaging breaks the metricity of geometry. We reinterpret the back-reaction within macroscopic gravity in terms of the non-metricity of averaged geometry. This interpretation extends the effect of back-reaction beyond mere dynamics to the kinematics of geodesic bundles. With a 1 + 3 decomposition of the spacetime, we analyse how geometric flows are modified by deriving the Raychaudhuri and Sachs equations. We also present the modified forms of Gauss and Codazzi equations. Finally, we derive an expression for the angular diameter distance in the Friedmann Lemaître Robertson Walker universe and show that non-metricity modifies it only through the Hubble parameter. Thus, we caution against overestimating the influence of back-reaction on the distances.
Equine Granulocytic Anaplasmosis: A Systematic Review and Meta-Analysis on Clinico-Pathological Findings, Diagnosis, and Therapeutic Management
Authors: Bogdan Andreea Monica , Mitrea Ioan Liviu , Ionita Mariana
Published: June 2024

Equine granulocytic anaplasmosis (EGA) is a tick-borne disease affecting horses worldwide, caused by Anaplasma phagocytophilum. The disease ranges from non-specific clinical signs to fatal outcomes. This paper aimed to analyze EGA cases reported in peer-reviewed journals, particularly on clinico-pathological findings, diagnosis, and therapeutic management. Overall, 189 clinical cases from 31 publications were included in the study. Extensive symptomatology for the EGA cases was reported, of which mostly was fever (90.30%), followed by limb edema (48.51%), anorexia (41.79%), depression (32.84%), icterus (22.39%), ataxia (17.91), tachycardia (16.42%), and lethargy (15.67%). Laboratory tests revealed thrombocytopenia (90.32%), anemia (75%), decreased hematocrit (70.59%), leukopenia (55.88%), lymphopenia (58.14%), and neutropenia (41.67%) as the most common hematological abnormalities. For a subset of tested animals, hyperbilirubinemia (20/29), hyperfibrinogenemia (13/15), and hyponatremia (10/10) were also reported. The diagnosis was established by microscopic identification of morulae (in 153 cases), and/or PCR (120 cases), isolation (1 case), or serology (56 cases). For treatment, oxytetracycline was used in the majority (52.24%) of EGA cases, but recovery without antibiotherapy (10.34%) was also noted. In conclusion, the variety of clinical and pathological findings and the challenging therapeutic approaches reported suggest that EGA should be included in the differential diagnosis when fever occurs.
Improved Model Predictive Control Path Tracking Approach Based on Online Updated Algorithm with Fuzzy Control and Variable Prediction Time Domain for Autonomous Vehicles
Authors: Liu Binshan , Wang Zhaoqiang , Guo Hui , Zhang Guoxiang
Published: June 2024

The design of trajectory tracking controllers for smart driving cars still faces problems, such as uncertain parameters and it being time-consuming. To improve the tracking performance of the trajectory tracking controller and reduce the computation of the controller, this paper proposes an improved model predictive control (MPC) method based on fuzzy control and an online update algorithm. First, a vehicle dynamics model is constructed and a feedforward MPC controller is designed; second, a real-time updating method of the time domain parameters is proposed to replace the previous method of empirically selecting the time domain parameters; lastly, a fuzzy controller is proposed for the real-time adjustment of the weight coefficient matrix of the model predictive controller according to the lateral and heading errors of the vehicle, and a state matrix-based cosine similarity updating mechanism is developed for determining the updating nodes of the state matrix to reduce the controller computation caused by the continuous updating of the state matrix when the longitudinal vehicle speed changes. Finally, the controller is compared with the traditional model prediction controller through the co-simulation of CARSIM and MATLAB/Simulink, and the results show that the controller has great improvement in terms of tracking accuracy and controller computational load.
Exploring User Attitudes and Behavioral Intentions towards Augmented Reality Automotive Assistants: A Mixed-Methods Approach
Authors: Wan Fucheng , Teng Jian , Feng Lisi
Published: June 2024

As augmented reality (AR) technology is increasingly permeating the automotive industry, this study investigates users’ attitudes towards AR automotive assistants and their impact on usage behavior. Using the theory of reasoned action (TRA) and integrating insights from the Kano model, critical factors driving user acceptance and engagement were identified. The research reveals that trust in AR technology, perceived utility, and ease of interaction are prioritized by users. Clustering analysis identified three distinct user groups: a ‘Safety-Conscious Group’, a ‘Technology Enthusiast Group’, and an ‘Experience-Seeking Group’, each displaying unique preferences towards AR features. Additionally, a support vector machine (SVM) model effectively predicted user behavior with a training set accuracy of 89.96%. These findings provide valuable insights for the design and marketing of AR automotive assistants, acknowledging both essential features and delighters identified through the Kano model. By understanding user preferences and expectations, tailored AR solutions can be developed to enhance user satisfaction and adoption rates in the automotive sector. Moreover, this research contributes to the sustainable development goals related to the automotive industry by fostering innovation in vehicle technology, promoting eco-friendly driving practices, and enhancing overall mobility efficiency.
PEMBERDAYAAN ORANG DENGAN GANGGUAN JIWA (ODGJ) DALAM MENGENDALIKAN RESIKO PERILAKU KEKERASAN DI WILAYAH KERJA PUSKESMAS BABAKAN SARI KOTA BANDUNG
Authors: Fatah Vera Fauziah , Z Desmaniarti , Sasmita Anah
Published: June 2024

People with mental disorders (ODGJ) in Indonesia have increased. In West Java, 11.360 people suffered from severe mental disorders in 2017 and increased to 16.714 in 2018. Some ODGJ are treated in psychiatric hospitals because of violent behavior and when they are declared cured after being at home they are very at risk of violent behavior, so they need special handling as a form of prevention of mental disorders. To prevent this, ODGJ should be empowered to control their behavior, especially the risk of violent behavior, so that something unwanted does not happen. Handling ODGJ with the risk of violent behavior can be done with a prevention program, namely religious therapy: listening to audio murottal Al-Qur'an and deep breath relaxation. The deep breath relaxation and murottal Al-Qur'an techniques listened to through audio not only cause a calming effect on the physical body but also calm the mind so that it can reduce the risk of violent behavior. This community service aims to empower cadres and ODGJ in reducing signs of risk of violent behavior in Sukapura Village, Babakan Sari Health Center Working Area, Bandung City. This activity began with training 10 health cadres to help empower 16 ODGJ in helping to reduce signs of risk of violent behavior by listening to deep breath relaxation audio and murottal Al-Qur’an: Surat Al-Fatihah twice a day for 2 weeks. The results and outcomes of this activity are an increase in cadre knowledge related to the risk of violent behavior and how to control it and a decrease in feelings of risk of violent behavior in ODGJ.
A Retrospective Analysis of The Causes of Industrial Fires in Istanbul Occurring Between 2015 and 2020
Authors: Topyay Gökçe , Büyüker Sultan Mehtap
Published: June 2024

This study was conducted to analyze the causes of industrial fires that occurred in Istanbul from 2015 to the first half of 2020. An official application was made to the Istanbul Metropolitan Municipality Fire Brigade Department, which has archive data on this subject, to conduct the research and a sample set was created by filtering industrial fires from the data pool obtained after the approval of the application. In the analysis phase of the 4600 industrial fire data reached, the distributions of the fires according to years, the intended use of the property where the fire took place, the cause of the fire and the district where the fire took place were examined using the Chi-square analysis method. SPSS 22 software package was used in the analysis and the level of significance was determined as 0.05. The examination of the results of the analysis indicated that the leading cause of industrial fires in Istanbul between 2015 and 2020 was electrical equipment with a rate of 44.8%. Electrical equipment was followed by hot work equipment, heating equipment, cigarettes, flammable and explosive chemicals, cooking equipment and arson, respectively. In the study, the reasons of the fires obtained as a result of the analysis of the data were examined, a comparison with the US industrial fire statistics was made and recommendations for improving data and preventing the recurrence of industrial fires were made. In addition, it was emphasized that robust statistics on the causes of fires played an important role in the development of fire prevention strategies and legislation.
Environmentally-Friendly Recycled Leather‑Reinforced Composite: Thermal and Acoustic Properties
Authors: Kodaloğlu Murat , Akarslan Kodaloğlu Feyza
Published: June 2024

Increase in energy consumption and environmental pollution are some of the main problems of today. One of the ways to overcome these problems is to increase the use of recycled materials. Heat and sound insulation in buildings can play an important role in saving energy and reducing environmental pollution with composite materials made from recycled leather. This study investigates the possibility of reusing leather scraps. Composite material was produced by cutting leather waste for thermal and sound insulation of buildings into small pieces and pressing them in a mechanical mold using polyvinyl acetate binder. The effect of the thickness of the developed new leather-added composite materials on their thermal and acoustic insulation properties was examined. When the thermal and acoustic properties of the composites were evaluated, it was determined that the PVA/skin thicknesses forming the mixture varied depending on the mean temperature and frequency (Hz). As a result of the measurements, it was seen that the sound at the 3000 Hz frequency, to which the human ear is most sensitive, was absorbed by 61%.
Pembuatan Pupuk Organik Tofu Go Green dari Limbah Cair Tahu di Kelurahan Gedanganak Ungaran Timur
Authors: Septi Antika  , Nerischa Adisti Rahma Aulia  , Kristi Ramadhani  , Ryzky Dwi Mulyaningrum  , Muhammad Sultan Al-Zukhruf  , Sri Wahyuni
Published: June 2024

Environmental pollution by human activities is often found in the environment around residences that live close to industry in both the formal and informal sectors, one of which is the tofu factory. Gedanganak Village is one of the sub-districts located in West Ungaran sub-district, Semarang Regency. Gedanganak sub-district consists of several hamlets, where the residents make their living as laborers and tofu craftsmen. People who do not know how to use liquid waste from tofu factories can be overcome by providing information, education and training to process liquid waste from tofu factories into organic fertilizer to achieve food security and increase people's income in Gedanganak Village. There is a need for liquid waste processing in the tofu industry. One innovation that can be done to reduce tofu waste is by using it into Tofu Go Green products. The purpose of this empowerment is to provide empowerment regarding the use of tofu liquid waste into organic fertilizer in the Gedanganak Village Community. The methods used are education, training and demonstration The result of Community Empowerment with training in making organic fertilizer from tofu liquid waste is that the community is able to independently utilize tofu liquid waste which has not previously been utilized.
 
ABSTRAK
                Pencemaran lingkungan oleh aktivitas manusia kerap ditemui dilingkungan sekitar tempat tinggal yang bermukim dekat dengan industri baik sektor formal dan informal, sektor informal salah satunya adalah pabrik tahu. Kelurahan Gedanganak merupakan salah satu kelurahan yang terletak di kecamatan Ungaran Barat Kabupaten Semarang. Kelurahan Gedanganak terdiri dari beberapa dusun, dimana penduduknya bermata pencarian sebagai buruh dan pengrajin tahu. Masyarakat yang tidak mengetahui bagaimana pemanfaatan limbah cair pabrik tahu dapat diatasi dengan memberikan informasi,edukasi, dan pelatihan mengolah limbah cair pabrik tahu menjadi pupuk organik untuk mewujudkan ketahanan pangan dan menambah penghasilan masyarakat di Kelurahan Gedanganak. diperlukannya pengolahan limbah cair pada industi tahu tersebut, salah satu inovasi yang dapat dilakukan untuk mengurangi limbah tahu tersebut yaitu dengan memanfaatkannya menjadi produk Tofu Go Green. Tujuan dari pemberdayaan ini adalah untuk memberikan empowerment mengenai pemanfaatan limbah cair tahu menjadi pupuk organik pada Masyarakat Kelurahan Gedanganak. Metode yang digunakan adalah edukasi, pelatihan dan demonstrasi. Hasil dari Pemberdayaan Masyarakat dengan pelatihan pembuatan pupuk organik dari limbah cair tahu yaitu masyarakat mampu mandiri untuk memanfaatkan limbah cair tahu yang sebelumnya belum dimanfaatkan.
Upaya Peningkatan Pengetahuan Remaja dalam Deteksi Dini Kanker Payudara dengan Pemeriksaan Payudara Sendiri (SADARI) di SMP Muhammadiyah 8 Surakarta
Authors: Wulandari Retno , Desy Widyastutik  , Wijayanti  , Deny Eka W
Published: June 2024

Data from Riskesda in 2013 and 2018 shows an increase in the prevalence of cancer in Indonesia from 1.4% to 1.49%. The prevalence of cancer in Indonesia based on age groups shows that a significant increase begins to occur at ages above 35 years. Screening is a government effort or a simple and easy test carried out on healthy populations with the aim of distinguishing people who are sick or at risk of contracting disease from healthy people. One form of increasing public awareness about the symptoms and signs of cancer is providing public education about breast self-examination (BSE). Counseling was carried out to 15 female students at SMP Muhammadiyah 8 Surakarta and the results showed that 100% of the students were able to do BSE themselves.
 
ABSTRAK
                Kanker payudara adalah jenis kanker yang menduduki urutan kedua terbanyak di dunia pada wanita. Berdasarkan survei dari World Health Organization (WHO) di tahun 2018, kanker payudara dialami oleh 8% hingga 9% wanita di dunia (WHO, 2018). Tahun 2018 kanker payudara menyebabkan kematian kedua dari total keseluruhan semua jenis kanker (348.809 kasus) pada wanita di Indonesia, kanker payudara menyumbang sebesar 58.256 (16,7%) (Kemenkes RI, 2021). Skrining adalah upaya pemerintah atau tes yang sederhana dan mudah yang dilaksanakan pada populasi masyarakat sehat yang bertujuan untuk membedakan masyarakat yang sakit atau beresiko terkena penyakit di antara masyarakat yang sehat. Salah satu bentuk peningkatan kesadaran masyarakat tentang gejala dan tanda-tanda kanker salah satunya adalah pemberian edukasi masyarakat tentang  pemeriksaan Payudara sendiri (SADARI). Penyuluhan dilakukan kepada siswi di SMP Muhammadiyah 8 Surakarta sebanyak 15 siswi didapatkan hasil bahwa  100 % siswa sudah dapat melakukan SADARI sendiri.
Peningkatan Kapasitas Tim Pendamping Keluarga (TPK) dalam Melakukan Surveilan pada Program Percepatan Penurunan Stunting di Kabupaten Sragen
Authors: Mulyasari Indri , Puji Afiatna  , Moneca Diah Listiyaningsih  , Anisa Puspitasari
Published: June 2024

Nutrition surveillance data related to stunting is important as a basis for program formulation. The skills of the data collection team in nutrition surveillance determine the quality of the data. One of the roles of the family assistance team is to collect data using both interviews and anthropometric measurements. Lack of skill in collecting data can lead to misinterpretation, which can lead to ineffective nutrition programs. Training activities for family support teams related to interview techniques and anthropometric measurements were carried out to overcome these problems. The methods used were lectures, demonstrations, and simulations. The results of the activity are expected to improve the skills of the family support team in collecting nutrition surveillance data. After the activity, the knowledge of the family support team increased. The skills of the family support team still need to be refreshed regularly because there are still misperceptions related to interview techniques. In addition, anthropometric measurement errors were still found, especially in measuring mid-upper arm circumference and height.
 
ABSTRAK
Data surveilan gizi terkait stunting penting sebagai dasar perumusan program. Keterampilan tim pengumpul data dalam surveilan gizi menentukan kualitas data. Salah satu peran TPK adalah mengumpulkan data baik menggunakan metode wawancara maupun pengukuran antropometri. TPK yang kurang terampil dalam mengumpulkan data dapat menyebabkan interpretasi yang keliru yang dapat menyebabkan program gizi menjadi kurang efektif. Kegiatan pelatihan bagi TPK terkait teknik wawancara dan pengukuran antropometri dilaksanakan untuk mengatasi masalah tersebut. Metode yang digunakan adalah ceramah, demonstrasi, dan simulasi. Hasil kegiatan diharapkan dapat meningkatkan keterampilan TPK dalam mengumpulkan data surveilan gizi. Setelah kegiatan pengetahuan TPK meningkat. Keterampilan TPK masih perlu mendapatkan penyegaran secara berkala karena masih ditemukan kesalahan persepsi terkait teknik wawancara. Selain itu, masih ditemukan kesalahan pengukuran antropometri terutama pada pengukuran lingkar lengan atas dan tinggi badan.
“Client health is part of my job”: A qualitative study of attitudes and experiences of legal personnel in British Columbia’s Downtown Community Court
Authors: Kenyon Kristi Heather , Garcia Regiane , Chukwudozie Ada
Published: June 2024

Established in Vancouver in 2008, British Columbia’s Downtown Community Court (DCC) is Canada’s first community court. Set up specifically to address offences stemming from mental illness, substance use and poverty, the court brings together justice, health and social services, offering a tailored response to the cycle of reoffending and public safety concerns in the city’s core. Focusing on the perspectives of legal actors, we examine the court as an unexpected site of health intervention. This qualitative interview-based study explores how judges, crown counsels and defence lawyers perceive their role and that of the court in relation to the health and wellbeing of court clients. Our findings show that legal personnel typically see health as a central part of the court’s intervention and similarly view client health as a critical part of their own jobs. Respondents describe the court’s ability to engage with those facing complex health and legal issues as unique, attributing it to its legal professionals’ holistic view of their roles, the court’s strategic community location and its unusual structure, which facilitates information sharing and attracts personnel invested in its mandate. The article identifies three primary needs: 1) enhanced education on client health for legal professionals, 2) nuanced metrics to evaluatethe court’s health impacts and, 3) longitudinal client-centred research to measure the DCC’s long-term effects on health.
The mental health of Indigenous Peoples during the COVID-19 pandemic: A scoping review
Authors: Ponton Sarah J. , Gabriel Mikaela , Lu Jay , Stewart Suzanne , Strebel Roy , Mirza Sabina
Published: June 2024

Indigenous Peoples face significant disparities related to mental health and well-being due to colonization and its ongoing impacts, further impacted by COVID-19. Following Arksey and O’Malley’s six-stage framework and Bartlett’s Indigenous Two-Eyed Seeing approach, a reflexive review of the literature about Indigenous mental health during the pandemic was undertaken. Consultant interviews were also completed, and thematically organized, with Indigenous People from three Indigenous-serving mental health organizations in Ontario. Key themes included: highlighting Indigenous voices, historical context, challenges and strengths in culturally based services, virtual transition, financial support for Indigenous services, health service delivery and well-being, and culture and community connection. The themes bridge gaps in service provision, the mental health impacts of loss of connection with community due to pandemic restrictions, how mental health supports can be improved, and which services provided during the pandemic should continue. This review provides service providers clear recommendations based on the findings to help improve Indigenous mental health and service provision.
How judges in Canadian criminal courts define intimate partner violence
Authors: Bowns Ava J. , Giesbrecht Crystal J. , Bruer Kaila C.
Published: June 2024

Intimate partner violence (IPV) is a substantial problem in Canada, leading to over 100,000 victims reporting to police in Canada annually. However, there is no legal definition or Canadian Criminal Code offence for IPV. The purpose of this study was to examine how judges in the Canadian prairie provinces (Alberta, Saskatchewan, and Manitoba) define IPV in criminal cases. One hundred full-text, written judicial decisions from 2016 to 2022 were analyzed. Findings indicate that judges tend to discuss IPV as it relates to sexual and psychological violence; threats, coercive control, and physical violence; isolation and stalking; economic abuse and threats to take children away. Given that current Canadian law does not recognize psychological abuse as a criminal offence, this may signal a need for the creation of a legal definition of IPV to align with how more directly it is being discussed in courtrooms.
Seçmeli Bilim Uygulamaları Dersine İlişkin Yürütülen Araştırmaların Tematik İçerik Analizi
Authors: Muradoğlu Bahar , Yiğit Nevzat , Mazlum Güven Ebru
Published: June 2024

Bilim Uygulamaları dersi ile öğrencilere bilimsel süreç becerileri gibi pek çok beceriyi kazandırma ve akademik başarıyı artırma hedeflenmektedir. Oysaki alan yazındaki araştırmalarda, bu dersin uygulanmasına ilişkin birçok sorunun varlığı göze çarpmaktadır. Bu nedenle derse ilişkin yapılan araştırmaların içerik analizlerinin yapılarak genel durumu ortaya çıkarmak ve alınabilecek önlemleri tartışmaya açmak gerekli görülmüştür. Bu çalışma ile Bilim Uygulamaları dersine yönelik farklı veritabanları taranarak elde edilen, 2013-2021 yılları arasında gerçekleştirilmiş 35 çalışma, tematik içerik analizi yöntemiyle çeşitli parametreler açısından incelenmiştir. Elde edilen bulgular, ders kapsamında hazırlanan etkinliklerin öğrencilerin derse ilişkin görüşlerine ve pek çok becerisine olumlu katkısını vurgulamakla birlikte, dersin etkin bir şekilde işlenmemesi sebebiyle öğrenciye olumlu katkılarının oldukça sınırlı olduğunu göstermiştir. Bunun yanısıra incelenen çalışmalarda karma yaklaşıma diğer yaklaşımlara oranla daha az başvurulmuştur. Bilim uygulamaları dersi kapsamında kazandırılmak istenen bilimsel süreç ve yaşam becerilerinin nasıl daha etkili edinilebileceğine yönelik ayrıntılı açıklamalar geliştirmeye olanak vermesi açısından karma yaklaşımla yürütülen çalışmaların sayısı artırılabilir.
Pengaruh Daun Muda dan Daun Tua Terhadap Aktivitas Antioksidan dan Kualitas Mutu Teh Herbal Daun Soyogik (Saurauia bracteosa DC.)
Authors: Maleke Zefanya F. W. , Runtuwene Max Revolta John , Kamu Vanda Selvana
Published: June 2024

ABSTRACT
This study was aimed to determine the effect of young and old leaves on the quality of soyogik leaf (Saurauia bracteosa DC.) herbal tea. Soyogik leaf herbal tea was made by drying it in an oven at 50˚C for 150 minutes, then testing for phytochemical screening, free radical scavenging activity, and quality standard. Phytochemical screening showed that young and old soyogik leaves contained triterpenoids, flavonoids, saponins and tannins. The antioxidant test results showed that free radical scavenging activity of young soyogik leaves (70.637%) were higher than that of old soyogik leaves (70.204%). Soyogik leaf herbal tea from young leaves had the best quality with the criteria of water content 7.664%; ash content 6.344%; acid insoluble ash content 0.077%; crude fiber 15.36%; metal contamination Pb (0.22 mg/kg), Cd (<0.00009 mg/kg), As (0.15 mg/kg); color with value L = 63.5, a* = 44.8, and b* = 71.2; and the aroma/smell and taste somewhat liked by the panelists. The overall results obtained show that soyogik leaves have potential as herbal teas and the degree of aging can affect the quality of soyogik leaf herbal teas.
Keywords: herbal tea, soyogik, Saurauia bracteosa DC., antioxidants, quality
 
ABSTRAK
Penelitian ini bertujuan untuk mengetahui pengaruh daun muda dan daun tua terhadap kualitas mutu teh herbal daun soyogik (Saurauia bracteosa DC.). Pembuatan teh herbal daun soyogik dilakukan dengan pengeringan oven pada suhu 50˚C selama 150 menit, kemudian dilakukan skrining fitokimia, pengujian aktifitas penangkal radikal bebas, dan uji standar mutu. Skrining fitokimia menunjukkan bahwa daun soyogik muda dan tua mengandung triterpenoid, flavonoid, saponin dan tanin. Hasil pengujian antioksidan menunjukkan bahwa aktivitas penangkal radikal bebas daun soyogik muda (70,637%) lebih tinggi dibandingkan dengan daun soyogik tua (70,204%). Teh herbal daun soyogik dari daun muda mempunyai kualitas paling baik dengan kriteria kadar air 7,664%; kadar abu 6,344%; kadar abu tak larut asam 0,077%; serat kasar 15,36%; cemaran logam Pb (0,22 mg/kg), Cd (<0,00009 mg/kg), As (0,15 mg/kg); warna dengan nilai L = 63,5 a* = 44,8, dan b* = 71,2; dan aroma/bau serta rasa yang agak disukai oleh panelis. Keseluruhan hasil yang diperoleh menunjukkan bahwa daun soyogik dapat berpotensi sebagai teh herbal dan tingkat ketuaan daun dapat mempengaruhi kualitas teh herbal daun soyogik.
Kata kunci: teh herbal, soyogik, Saurauia bracteosa DC., antioksidan, kualitas mutu
Pengontrolan Bahaya Kebakaran Berbasis IOT pada Ruang Server SMFR Balai Monitor Spektrum Frekuensi Radio Kelas II Batam
Authors: Setiawan Eko , Nurhatisyah Nurhatisyah , Nanra Suwadi
Published: June 2024

Monitoring the security of the SMFR server room is one of the problems at the Batam Class II Radio Frequency Spectrum Monitoring Center, especially against fire hazards.
Purpose: To control hazards that can interact with the internet as part of the IoT (Internet of things) so that early detection of fires can be carried out at any time and via a smartphone that displays data from fire sensors, smoke sensors and sensors, while the control measures are activation of alarms, exhausts, openings doors and windows as well as LEDs as fire extinguisher activation indicators so as to minimize equipment damage in the SMFR server room.
Methodology: The implementation method used is the design and manufacture of server room miniatures, the design and manufacture of a control system using the Arduino Mega 2560, the design and manufacture of IoT monitoring and control as well as tool testing.
Results: From the test results, when the input sensor data, namely fire, temperature and smoke, do not meet these conditions, there will be no fire, all fire handling actions are not active. However, if all the conditions for the input sensor data are met and the threshold value is determined, i.e. there is a smoke fire >37 ppm and a temperature >37? then these conditions will trigger a fire so that all fire handling actions in the form of alarms, exhausts, doors, windows, and LEDs will active. As well as sending fire notifications to Smartphones so that fire events can be detected and handled early. IoT-based testing is carried out using a 4G network, The test results show that Blynk supports capable IoT but depending on the type of real-time connection, the type of network connection used provides varying delay effects. The average delay that 4G produces is  1 to 5 seconds.