bluuebunny/crossref_metadata_2025 huggingface dataset:
Letrozole and ovarian hyperstimulation syndrome: Retrospective cross-sectional study
Authors: Nikfarjam Elham , Eftekhar Maryam , Fatehi Hanieh , Arabian Sahereh
Published: May 2024

Background: Recently, letrozole has been used to prevent moderate to severe ovarian hyperstimulation syndrome (OHSS) in assisted reproductive technology cycles due to its estrogen-reducing and androgen-increasing effects on the ovaries, affecting granulosa cells, and reducing vascular endothelial growth factor production.
Objective: This study aimed to investigate the impact of letrozole consumption in preventing OHSS in infertile women with polycystic ovarian syndrome undergoing in vitro fertilization.
Materials and Methods: In this cross-sectional study, among 1743 medical records of infertile women who were scheduled for oocyte retrieval at Research and Clinical Center for Infertility, Yazd, Iran. Data of 343 women with polycystic ovarian syndrome diagnosis and at risk of OHSS was extracted from March 2022–2023. The stimulation was carried out using a flexible gonadotropin releasing hormone (GnRH) antagonist protocol. Women were divided into 2 groups based on whether they received letrozole or not. In the letrozole group, 2.5 mg letrozole twice daily was continued from the trigger day, while in the control group, women did not receive letrozole. The parameters of OHSS severity, hospitalization rates, and the need for albumin prescription were analyzed.
Results: 89 women in the letrozole and 254 women in the control group were examined. There was no statistically significant difference between groups in terms of age and body mass index; however, anti-Mullerian hormone was significantly higher than control group (7.53 ± 4.61 vs. 5.47 ± 3.63, p < 0.001). The parameters of OHSS severity, hospitalization rates, and the need for albumin prescription showed no significant differences between the groups.
Conclusion: Recent study indicates that incorporating letrozole into the treatment of GnRH antagonists and cabergoline does not reduce the OHSS severity.
Key words: Letrozole, Polycystic ovary syndrome, Ovarian hyperstimulation syndrome, Assisted reproductive technologies.
The Importance of Analysis of Judicial Circumstances in the Sentence Dosimetry Process
Authors: Da Silva Cliciano , De Moura Lino Janildes
Published: May 2024

The Constitution plays an important role as a point of reference for the critical analysis of the criminal system, not only because it derives from the legal assets susceptible to punitive protection, but also and among other reasons, because the principles enshrined as a government norm in the Penal Code governing The imposition of sanctions is a clear development of the constitutional text and doctrine that the Constitutional Court has been building with its pronouncements, in the form that criminal law must acquire. The dosimetry of punishment in Brazil takes a three-step approach, pushing the system of fixed sanctions implemented by the legislature or the full discretion of the judge, promoting, on the other hand, a distribution of functions between the two, as he chooses the minimum and maximum sentence levels and dosage parameters, and this determines the sanction in the specific case from the legal criteria. In this sense, the present research aims to analyze the importance of analyzing judicial circumstances in the process of penalty dosimetry. The specific objectives are: to present a brief history of criminal legislation in Brazil, to review the most recent literature on the application of the penalty and its principles, to analyze the relationship between the dosimetry of the penalty and judicial circumstances and to point out cases in the jurisprudence that materialize the revised theory. Thus, given the relevance of the theme in the current legal scenario, the research is justified by discussing a contemporary theme. Through research on the principles of exceptionality, state of innocence, motivation of decisions and proportionality and the dosimetry of the penalty, possible judgments of the judge that relate the dosimetry of the penalty with the principles of human rights will be discussed. The judge should take charge of the evidence produced in relation to the facts that, in his opinion, influence the minor or major measure of the exact penalty to be imposed. The lack of motivation currently constitutes a violation of the constitutional guarantee of due process and absolute grounds for invalidity under the Criminal Procedure Code.
Shallow tunneling's impact on surface settlements
Authors: Djenane Mohamed , Bezih Kamel
Published: May 2024

The research described in this paper deals with the impact of shallow tunneling on surface settlements in urban areas. The study focuses on carrying out a numerical analysis and a parametric geotechnical study to investigate the effects of tunnel excavation on the surface ground, particularly with regard to distortion and potential damage to structures above the tunnel. To carry out the study, the researcher used a finite element method (FEM) software package called Plaxis. This software is commonly used for geotechnical analysis and allows simulating and analyzing the subsurface conditions in Algiers underground in the context of excavating a shallow tunnel. The New Austrian Tunnelling Method (NATM) excavation method was chosen for the study. The results of the numerical analysis are presented in terms of displacements. The results indicate that ground flow has a significant influence on ground movement, probably contributing to surface settlement. However, the effect of tunnel excavation on the lowering of the water table and Young's modulus (a measure of soil stiffness) is relatively small in comparison. The research provides valuable information on the potential impacts of shallow tunneling in urban areas and the factors that play a crucial role in determining the extent of ground movement and surface settlement. By using numerical analysis and conducting a parametric geotechnical study, and gives valuable insights into the potential impacts of shallow tunnelling in urban areas and the factors that play a crucial role in determining the extent of ground movements and surface settlements. By using numerical analysis and conducting a geotechnical parametric study, and contributes to a better understanding of the behavior of the ground during tunnelling operations in Algiers. The findings can be helpful in designing future tunnelling projects to mitigate potential risks to structures and infrastructure located above the tunnels.
Influence of Concrete Compressive Strength on L-Shaped Shear Wall Performance in Buildings within High-Seismicity Zones
Authors: Merabti Salem , Guelmine Layachi
Published: May 2024

Reinforced concrete mid-rise structures are supported by shear walls to withstand lateral forces resulting from earthquakes. In this context, the presence of openings in these walls is essential both functionally and aesthetically. This study employed L-shaped shear walls with varying vertical opening ratios, ranging from 15% to 50%, and compressive strengths ranging from 20MPa to 40MPa in a ten-story building. The study results demonstrate the significant role played by openings and the compressive strength of concrete in reinforced concrete walls to ensure buildings withstand earthquake forces. In this regard, we have developed reference models that adhere to seismic design principles and utilize optimized dimensions for openings based on the compressive strength of the concrete.
Substitution of tourism trips as a result of the COVID-19 pandemic—an empirical verification
Authors: Niezgoda Agnieszka , Markiewicz Ewa
Published: May 2024

Purpose: The aim of this chapter is to empirically verify the thesis (set out in the previous work) regarding the substitution changes in the tourism market caused by the COVID-19 pandemic. The question was posed as to whether the travel substitution caused by the pandemic concerned substitution internal or external to the offer of the tourism market. Design/methodology/approach: Qualitative research was conducted on the supply side and the demand side of the tourism market. The supply-side research comprised a direct (non-standardised) interview among representatives of the three main tour operators organising tourist trips on the Polish market. The demand study used a direct standardised interview method using an interview questionnaire. Findings: The results of the research showed internal substitution processes in the tourism market triggered by the COVID-19 pandemic. The changes affected trips to a slightly greater extent in 2020 than in 2021. The research showed lower external substitution, meaning that during the pandemic consumers did not want to give up tourism trips. Research limitations/implications: The research confirms the findings of other authors that the pandemic treated as a transformative force in tourism and hospitality, while the relatively short time after its end prevents long-term conclusions. Practical implications: The results can be used by service providers, to anticipate changes caused by contingencies, as well as to predict trends in tourism product design. Social implications: The research indicates the direction of change that a pandemic may provide a starting point for further observations. Originality and value: Most of the analysis is limited to quantitative phenomena related to the reduction of tourism trips as a result of the COVID-19 pandemic. The originality of the article is based on the analysis of the substitution processes in the tourism market by internal and external substitution. The added value is the simultaneity of the study on both the demand and the supply side of tourism.
Restrukturyzacje transgraniczne w świetle klauzuli nieruchomościowej oraz obowiązków spółki nieruchomościowej jako płatnika
Authors: Łopatek Robert
Published: May 2024

Skutki podatkowe procesów restrukturyzacyjnych wywołują wątpliwości przede wszystkim z uwagi na wielości podmiotów, które uczestniczą w takich procesach, oraz ich rolę. Celem artykułu jest zatem poddanie analizie klasyfikacji potencjalnego przychodu uzyskanego w wyniku działań restrukturyzacyjnych jako „zysków z przeniesienia własności majątku” w świetle stanowisk reprezentowanych przez organy podatkowe oraz sądy administracyjne. Ponadto rozważona zostanie problematyka obowiązków spółki nieruchomościowej jako płatnika w związku z dokonaniem działań restrukturyzacyjnych.
Dyskursywny obraz Łodzi w mediach
Authors: Gaze Mateusz
Published: May 2024

Publikacja zawiera odpowiedź na pytanie, czy media wzmacniają i/lub wyciszają stereotypy o Łodzi. Przystępując do badania, określono następujące problemy poznawcze: co pisze się o Łodzi, jak się pisze oraz czy to, jak się pisze, podlega refleksji samych dziennikarzy, a zatem, czy możliwe jest zbadanie metadyskursu. Już na etapie wyboru tematu czy selekcji materiału dziennikarz dokonuje subiektywnego przedstawienia wybranych elementów Łodzi. Z lingwistycznego punktu widzenia istotny jest proces, podczas którego na bazie zebranych materiałów i opinii dziennikarz tworzy tekst, nadając mu konkretną strukturę językową. Dobiera odpowiednie środki językowe, by osiągnąć określone wcześniej intencje. 
Celem monografii jest analiza wizerunku Łodzi w różnych typach mediów (prasa, internet, telewizja). Źródła dobrano tak, by wychwycić różnice między wizerunkiem Łodzi w mediach o zasięgu ogólnopolskim a wizerunkiem w mediach o zasięgu lokalnym.
Batutą i skalpelem. Ciało w zawodach wysokospecjalistycznych
Authors: Byczkowska-Owczarek Dominika
Published: May 2024

Monografia “Batutą i skalpelem. Ciało w zawodach wysokospecjalistycznych” prezentuje wyniki socjologicznych badań jakościowych przeprowadzonych wśród przedstawicieli zawodów neurochirurga i dyrygenta orkiestrowego. W badaniach zastosowano metodologię teorii ugruntowanej oraz szereg jakościowych technik gromadzenia danych. Książka podzielona jest na sześć rozdziałów. We Wprowadzeniu Autorka przedstawia cel i okoliczności powstania monografii, a także jej najważniejsze założenia teoretyczne. Rozdział 2. Praca w zawodzie neurochirurga prezentuje historię tego zawodu, konteksty instytucjonalny, kulturowy, grupowy jego wykonywania, a także proces pracy poprzez ciało, którego główną charakterystyką jest dostosowywanie się. Rozdział 3. Praca w zawodzie dyrygenta orkiestrowego przedstawia historię zawodu, uwarunkowania odgrywania tej społecznej roli oraz specyfikę pracy poprzez ciało w tym zawodzie, której główną charakterystyką jest uzewnętrznianie. Rozdział 4. Charakterystyka pracy poprzez ciało w badanych zawodach obejmuje analizę procesu kształcenia, realizowania przywódczych aspektów roli oraz relacji pomiędzy specyfiką wykonywanego zadania a sposobem pracy poprzez ciało. We Wnioskach autorka proponuje koncepcję społecznego konstruowania cielesności w obszarze roli zawodowej, a także szereg empirycznie ugruntowanych pojęć składających się na tę koncepcję. Monografię zamyka rozdział 6. Metodologia i naturalna historia badania, w którym opisane zostały kwestie metodologiczne badań, w tym wykorzystane techniki gromadzenia danych, problemy w trakcie prowadzenia badań, kwestie etyczne czy znaczenie roli badaczki.
Comparative Gross Architectural Studies on the Skull of Male Chital Deer (Axis axis) and Sambar Deer (Rusa unicolor) as an Aid in Wildlife Forensics
Authors: Lade D. , Podhade D.N. , Vaish R. , Singh S. , Rai A. , Guntoju S.
Published: May 2024

Background: Madhya Pradesh is rich in biodiversity having diversified flora and fauna. But now a days, apart from various threat like loss of habitat poisoning, accident, disease facing wildlife today and poaching remain one of the important causes for fauna declination. poaching remains one of important cause for fauna declination. Poaching of wild animals particularly chital and sambar deer is more for the meat, ornamental and trophy purposes. In forensic laboratory where there is lack of molecular facilities, comparative gross morphological study plays an important role in solving wildlife crime cases. skull is a best material to compare the closely relative species. hence, the study was conducted on comparative gross morphology of 4 male chital and sambar deer skull. Methods: The study was conducted 4 male adult skulls each of chital and sambar deer. The skulls were de-skinned and kept under maceration for a period of one month. The gross morphological differentiating features of dorsal surface, lateral surface, basal surface and nuchal surface were observed and recorded with the help of digital camera. Result: In this study, unique differentiating features were sufficient to distinguish among the skull of male chital and sambar. The facial tuberosity was present caudal to infraorbital foramen, dorsal to the superior third premolar tooth in chital deer, whereas; it was present dorsally the superior first molar tooth in sambar deer. Rostral extremities of nasal bones in skull of male chital deer were notched; however, these were blunt and without notch in the skull of male sambar deer. Incisive (Premaxilla) bone was directed upward in chital deer; whereas, it was directed caudally in case of sambar deer. The present comparative study will provide reliable information for identification of these closely related species specially needed for wildlife forensic cases.
Nueva Sede de la Ensad (Escuela Nacional Superior de Arte Dramático) en el Centro Histórico de Lima
Authors:   , Sarango Olaya Silvana
Published: May 2024

El presente proyecto es la Nueva sede de la Escuela Nacional Superior de Arte Dramático (ENSAD) ubicado en el distrito del Centro Histórico de Lima, en el sector de la Plaza Francia. Se desarrolla bajo el concepto de generar atmósferas, espacios escénicos y el dramatismo. Se emplaza al lado de un monumento histórico (Hospicio Bartolomé Manrique) y cuenta con varias edificaciones de carácter arquitectónico (casonas republicanas en Jr. Rufino Torrico y Jr. Camaná, edificios modernistas de la época de los 40s inspirados en la arquitectura de ‘Le Corbusier’ hacia la Av. Wilson) por lo que el reto fue reinterpretar su lenguaje de una manera contemporánea para que se adecúe al entorno inmediato. Como aporte urbano, se propone conectar la Plazuela Elguera (ubicado en la Av. Wilson con Jr. Quilca) con la Plaza Francia mediante el Jr. Rufino Torrico y regenerar la zona que en la actualidad luce en muy mal estado y es muy peligroso transitar mediante el presente proyecto y generar una vía de coexistencia dándole prioridad a los peatones. Se propone que el primer nivel de la escuela sea permeable, con locales comerciales, cafeterías, galerías de exposiciones y adicionalmente se ha generado una plaza en el interior del proyecto como lugar de encuentro garantizando la animación en la zona.
Key Considerations: Alleviating Chronic Food Insecurity in South Sudan
Authors: Moro Leben Nelson , Tong Deng Anei
Published: May 2024

The Republic of South Sudan has experienced chronic food insecurity for decades and particularly in the last five years. This chronic food insecurity is a result of a combination of factors, including protracted conflicts, socio-economic fragility, lack of infrastructure, climate change and conflicts and wars in Sudan, Ukraine and the Middle East. In response, the South Sudan Government, UN agencies and international and national non-governmental actors have adopted measures to deal with the ongoing humanitarian crisis. Investing in the agricultural sector may offer a sustainable route to potentially alleviate the chronic food insecurity crisis. This brief describes the scale of the food insecurity facing populations in South Sudan. It also analyses the causes of food insecurity, responses by government and non-government actors and partners, and offers considerations for these actors to support ending food insecurity, especially via bolstering agriculture and livelihoods. This brief draws on published texts, grey literature (especially government and non-governmental organisation reports), print and online media releases, and discussions with politicians and civil servants from institutions that focus on food insecurity in South Sudan.
Isotopic composition of carbon and oxygen in Upper Carboniferous-Lower Permian carbonate rocks of the Losinoostrov Formation (Subpolar Urals, Kozhim River)
Authors: Inkina N.
Published: May 2024

The Paleozoic section on the Kozhim River of the Subpolar Urals is the best sequence of the northern Urals. The border of Carboniferous-Permian deposits are observed on the opposite banks of the Kozhim River and are represented by two types of sections: on the right bank — the Kozhym skeletal mound, on the left bank — depression deposits of mixed composition (Losinoostrov Fm.). The article presents the first information on the isotopic composition of carbon and oxygen in the Lower Permian limestones of the Losinoostrov Fm. It is shown that the obtained data on the isotopic composition on the 13C–18O diagram are visually separated into three clusters. The first cluster with the lowest values of 13C (–0.3…1.1 ‰) and 18O (23.5…25.0 ‰) included the most intensively silicified rocks (siliceous bioclastic limestones, secondary silicitolites, siliceous-carbonate-argillaceous mixtolites and siliceous-argillaceous limestone). The third cluster, with the highest values of 13C (3.9…5.1 ‰) and 18O (26.0…26.8 ‰), includes bioclastic and peloid-micritic limestones. In this case, the 13C values correspond to the range of variations in the carbon isotopic composition indicated in review works on the chemostratigraphic correlation of Permian deposits. The second cluster occupies an intermediate position and is characterized by the values of 13C (2.0…2.8 ‰) and 18O (24.3…25.4 ‰). This cluster is predominantly represented by limestones enriched with terrigenous materials.
A comparison is made of the isotopic composition of the limestones of the Losinoostrov Formation with the coeval limestones of the Kozhim skeletal mound, which showed higher values of 13C and 18O in the latter.
Kreatív vagy sem? – A vezetői befolyásolás azonosítására tett kísérlet a közzétett számviteli beszámolók vizsgálatával
Authors: Denich Ervin , Budai Eleonóra , Hajdu Dániel
Published: May 2024

A befektetők döntéseik meghozatala érdekében számos tényezőt vesznek figyelembe, amikor befektetnek egy vállalkozásba. Ezek egyike a számviteli beszámolókból származó információ, amely a gazdasági élet fontos eleme, és ezenkívül a szakma érdekeit is szolgálja. Ebből adódóan igen lényeges, hogy a nyilvánosságra hozott számviteli beszámolók adatai jó minőségűek legyenek. Egyrészt azért, mert a piacgazdaság megfelelő működéséhez elengedhetetlen, hogy a piac szereplői számára szükséges információk megfelelő időben és minőségben rendelkezésre álljanak. Másrészt a 21. század elején a számviteli botrányok (Enron, WorldCom, Parmalat, Satyam) gyakoriságának növekedése világszerte rámutatott a pénzügyi beszámolók minőségi problémáira. Ennek tükrében kutatásunk egyfelől a vállalatirányítás és a kreatív számvitel közötti kapcsolatra irányult, ahol a kreatív könyvelés alkalmazása a vállalat gyengeségeire utalhat, másfelől pedig arra, hogy a nyilvánosságra hozott beszámolók milyen mértékben tekinthetők minőséginek. Tanulmányunkban a kreatív könyvelés és a vállalatirányítás közötti kapcsolatot a Transparency and Disclosure Index (TDI) segítségével vizsgáltuk, a nyilvánosságra hozott beszámolók minőségét pedig a módosított Jones-modellel. A TDI segítségével kapott eredmények alapján a vállalatirányítás és a kreatív számvitel között egy közepesen erős, negatív kapcsolat figyelhető meg. A módosított Jones-modellel kapott eredmények esetében a teljes befolyásolás t-statisztikával mérve negatív értéket vett fel a vizsgált időszakban, ami azt sugallhatja, hogy a vállalkozás vezetői a pénzügyi eredmény csökkentésére irányuló döntéseket hoznak. Tekintettel arra, hogy mindkét módszerrel nagyjából azonos eredményre jutottunk, a befektetői döntés meghozatala előtt érdemes figyelmet szentelni annak a kérdésnek, hogy vajon a nyilvánosságra hozott számviteli beszámolók ehhez megfelelő alapot biztosítanak-e.
BASIC ANXIETY IN JANE AUSTEN’S PRIDE AND PREJUDICE AND EMMA
Authors:   Faculty of Arts, Humanities and Social Sciences, University of Limerick, Limerick, Ireland, Djelloul Hana
Published: May 2024

This paper examines Jane Austen’s representation of the heroines of Pride and Prejudice and Emma, using Karen Horney’s psychosocial theory of basic anxiety that emphasizes the role of childhood experiences and the impact of socialization on an individual’s psychological development. Firstly, the examination shows certain episodes in the heroines’ early experiences that shape their adult identity and self-knowledge. The analysis reveals that those heroines are highly affected by their parents or chaperones, who themselves may suffer from neurotic problems that impede their ability to properly provide care and support for their children. Moreover, this research delves into how social norms and expectations affect the heroines’ self-image and worldview.
Çocuklarda Periferik Fasiyal Sinir Paralizisi ve Obezite: Tesadüften Fazlası mı?
Authors: Ozbudak Pınar
Published: May 2024

Periferik fasiyal sinir paralizisi (PFP) çocuk hastalıkları ve çocuk nöroloji polikliniklerinde sıkça karşımıza çıkmaktadır. Fizik muayene esnasında fazla kilolu oldukları gözlemlenen PFP hastalarından yola çıkılarak çocuklarda PFP ve aşırı kiloluluk ve obezite ilişkisinin araştırılması amaçlanmıştır. Çalışmaya 1 Nisan 2021 ve 31 Ekim 2022 tarihleri arasında tek merkezden Uluslararası Hastalık Sınıflandırması (ICD)-10 birincil ve ikincil G51.0 (fasiyal sinir paralizisi) tanısı alan 42 hasta dahil edildi. Hastaların yaş, cinsiyet, hastalığın ortaya çıkışından hastaneye başvuruya kadar geçen süre, başvuru sırasındaki House-Brackmann (HB) skoru ve PFP derecesi, 4. Hafta HB skoru, PFP etiyolojisi, vücut kitle indeksi (VKİ), aşırı kilo ve obezite dahil ilişkili hastalıkların varlığı retrospektif olarak kaydedildi. 18 yaşı doldurmuş hastalar, santral FP'li hastaları, verilerde eksiklikleri olan hastalar çalışma dışı bırakıldı. Verileri tam olan 30 PFP’li çocuk hasta çalışmaya dahil edildi ve bunların 22 tanesi idiyopatik olarak sınıflandırıldı. İdiyopatik grupta ve tüm kohortta PFP olan hastaların sırasıyla %73 (n=22) ve %70(n=18) 'inin VKİ'si 90. persentilin üzerindeydi. Her iki grupta kız cinsiyet daha yüksek görülse de cinsiyetler arasında anlamlı bir fark saptanmadı. Yüksek VKİ, aşırı kilolu ve obez hasta grubunda (VKİ >90. persentil; olasılık oranı [OR], 8; %95 güven aralığı [GA], 1,25 ila51,13; p < 0,05) istatistiksel olarak artmış Bell paralizisi olasılığı ile ilişkilendirildi. Aynı zamanda VKI>25kg/m2 olan idiyopatik PFP olan grupta ek hastalık oranı %53 (n=5 hipertansiyon, n=3 hipotiroidi), idiyopatik olmayan gruba göre daha yüksek saptandı, ancak istatistiksel olarak anlamlı fark saptanmadı. Bu sonuçlar aşırı kilo ve obezitenin çocuklarda artmış Bell paralizisi riski ile ilişkili olabileceğinin altını çizmektedir.
Development of the Need Satisfaction Perceived Online Scale
Authors: Gündüz Soytürk Merve , Eryılmaz Ali
Published: May 2024

This study aimed to develop the Need Satisfaction Perceived Online Scale to measure individuals' satisfaction of perceived basic psychological needs in online environments. The sample of the study consisted of a total of 856 university students aged between 18-25 years, 251 (184 Female, 67 Male) for scale adaptation study, 346 (277 Female, 69 Male) to perform exploratory factor analysis for scale development study and 289 (227 Female, 62 Male) to perform confirmatory factor analysis. Data collection instruments included “The Need Satisfaction Perceived Online Scale”, “The Basic Needs Satisfaction Scale of College Students”, “The Self-Disclosure Scale” and “Personal Information Form”. A scale of 12 items and 3 sub-scales was obtained, explaining 57.9% of the total variance. The observed fit values showed good fit. Significant positive correlations were obtained between the sub-scales of the instrument used for evaluating criterion-related validity and those of the corresponding developed scale (p
Agronomic evaluation and adaptability of Pinot gris to an environment with high grey mould disease pressure: a comparative analysis on 17 clones
Authors: Belfiore Nicola , Lovat Lorenzo , Zanchin Alessandro , Mian Giovanni , Gaiotti Federica , Franceschi Deborah , Marcuzzo Patrick , Tomasi Diego
Published: May 2024

The grapevine (Vitis vinifera L.) cultivar Pinot gris is an international variety that has spread world wide and is oneof the most important in Italy, especially in the northern regions where almost half of the world's total is grown. Over a three-year period (2019–2021), a comparative study was conducted on 17 clones to evaluate their agronomic aptitudes, susceptibility of grapes to Botrytis cinerea, fertility of buds, vigour, and oenological characteristics. We aimed to provide local viticulture with agronomic, sanitary status, and oenological indications that help to choose the genotype that best fits and enhances the clone/environment synergy. This is important given climate change, one of the most significant factors affecting viticulture. Hence, productive, qualitative, and health surveys were conducted on grapes during harvest. Vigour and vegetative/productive balance were also evaluated regarding the weight of the pruned wood. The Ravaz index and fertility of buds were studied when the inflorescences were separated and clearly visible (between DOY 131 and DOY 141 each year). The confirmation of the bunch was also evaluated (shape and number of wings) according to the Organisation Internationale de la Vigne et du Vin (OIV) descriptors. Through the use of digital photogrammetry, some descriptors of the cluster that most correlate with the severity of Botrytis cinerea were identified. In 2020 and 2021, microvinifications were carried out in white and with maceration of skins, respectively, following tested protocols. Sensory analysis of the wines was performed with a trained panel of experts. The study revealed interesting differences between clones concerning grapes' qualitative, productive, and sanitary aspects. Some clones stood out for their sugar accumulation, yield and resistance to Botrytis cinerea, as well as for the oenological olfactory profile. Statistical analysis highlighted that the severity of Botrytis cinerea and bunch rot was not correlated with the vigour of the plant but rather with the hardness of skin, content of soluble solids, soluble solids/total acidity ratio, pH, and total acidity. From the sensory analysis, several clones had a higher score for some descriptors in both study years and were more appreciated than others.
Korelasi antara Sarapan Pagi dengan Sindrom Dispepsia dan Aktivitas Fisik pada Anak Usia 10-12 tahun di Surakarta
Authors: Bogra Sufathonah Ridha , Rokhayati Evi , Anniazi Mas Ayu Lubna
Published: May 2024

Pendahuluan: Tujuh dari sepuluh anak yang berangkat sekolah tidak melibatkan diri dalam sarapan pagi, kebiasaan mengabaikan sarapan diidentifikasi sebagai salah satu pemicu terjadinya dispepsia. Individu dengan sindrom dispepsia cenderung berpartisipasi dalam aktivitas fisik secara lebih sedikit, seperti berjalan kaki dan kurang terlibat dalam kegiatan fisik dengan intensitas sedang hingga kuat. Tujuan dari penelitian ini adalah untuk mengetahui korelasi antara kebiasaan sarapan pagi dengan kejadian sindrom dispepsia dan aktivitas fisik pada anak-anak berusia 10 hingga 12 tahun di Surakarta.
Metode: Penelitian ini merupakan penelitian observasional analitik dengan desain cross-sectional yang memanfaatkan data primer. Sebanyak 140 individu menjadi sampel penelitian pada tahun 2023, yang diambil dari populasi SD Negeri 80 Ngoresan dan SD Negeri Wonosaren di Surakarta. Proses pengambilan sampel dilakukan dengan metode purposive sampling. Penelitian dilaksanakan dengan menyebarkan kuesioner kepada sampel, dan data yang terkumpul dianalisis menggunakan perangkat lunak SPSS. Uji statistik yang diterapkan mencakup uji univariat, uji bivariat dengan menggunakan Spearman Rank, serta uji multivariat dengan Regresi Linear.
Hasil: Terdapat hubungan yang signifikan antara sarapan pagi dengan kejadian sindrom dispepsia (p-value = 0.002). Tidak terdapat hubungan yang signifikan antara sarapan pagi dengan aktivitas fisik (p-value = 0.540). Pada analisis multivariat diketahui hubungan yang paling mempengaruhi sindrom dispepsia adalah mengonsumsi makanan asam.
Kesimpulan: Kejadian sindrom dispepsia dipengaruhi oleh perilaku sarapan dan berkorelasi lemah dengan penurunan aktivitas fisik.
Organic food: medical and social aspect.
Authors:   Tatarstan Academy of Sciences, Mingazova E. N. ,   Biomedical University of Innovation and Continuing Education of the State Scientific Center of the Russian Federation – A. I. Burnazyan Federal Medical Biophysical Center of the Federal Medical Biological Agency of Russia,   Kazan State Medical University, Gureev S. A. ,   Biomedical University of Innovation and Continuing Education of the State Scientific Center of the Russian Federation – A. I. Burnazyan Federal Medical Biophysical Center of the Federal Medical Biological Agency of Russia, Mingazov R. N. ,   N. A. Semashko National Research Institute of Public Health,   Research Institute for Healthcare and Medical Management of Moscow Healthcare Department
Published: May 2024

The article presents current information on trends in the consumption of organic food products in the world, information from foreign studies on their impact on public health. The market for these food products has grown significantly since the late 20th century and today represents a multi-billion dollar industry with distinct production, processing, distribution and retail systems. The relevance of studying the prevalence of consumption of organic food products among the population of various countries is increasing due to the increase in the modern world of demand and motivation among social groups of the population, especially among adherents of a healthy lifestyle. The purpose of the study is to review and analyze modern scientific foreign literature on the development of the organic food market from the standpoint of health conservation and medical and social perspectives. As a result of the review, it was revealed that the understanding currently clearly manifested in various social circles of the need to improve the level of quality of health of the individual and the population as a whole, the demand for the production of safe, micronutrient-rich, healthy food products, especially products of plant origin, actualize the expansion of production organic food products. In many countries around the world, there is an increase in consumer demand for organic food products; their regular consumers are people, mainly women, who care about their health, are physically active, have a higher level of education and income, and live mainly in high-income countries. The certain high cost of organic food products, depending on labor-intensive production methods and certification costs, often leads to unequal access to organic food products. The positive impact of organic foods on health status and the risk of developing chronic diseases is associated with a higher content of biologically active compounds and a lower content of substances harmful to health. Overall, large intervention and population-based studies are needed on the health effects of organic foods, comparing the quality, safety, bioactive compounds, nutritional and phytochemical value of foods in conventional and organic production systems using new research methods.
Organization of prevention and therapy of acne in adolescents at the current stage.
Authors:   Voronezh State Medical University. N. N. Burdenko” of the Ministry of Health of Russia, Golikova L. O. ,   Cosmetology clinic Lemark LLC, Antonenkov Yu. E. ,   Voronezh State Medical University. N. N. Burdenko” of the Ministry of Health of Russia
Published: May 2024

The organization of prevention and treatment of acne in adolescents, necessary to improve the quality of medical dermatological care, has not been studied enough. The purpose of the study: аnalysis of current and potential opportunities for organizing the prevention and treatment of acne in adolescents. Results. The pathophysiological mechanisms of acne development are being reviewed, considering the characteristics of the puberty period, however, the trends in introducing new approaches to the organization of prevention and treatment of acne in adolescents are not expressed, with the exception of antiandrogen therapy. The official organization of treatment for adolescents with acne considers that any stage of acne development is multifactorial and is based on an inflammatory process. The officially recommended main method of treating acne in adolescents is the combined use of topical agents, especially the combination of benzoyl peroxide and the retinoid adapalene. In complex cases, topical treatment is supplemented with systemic therapy with retinoids (isotretinoin). Prevention of side effects of topical treatment (dry skin, hyperemia or cheilitis) is achieved through the use of moisturizing cosmetics or cream with dexpanthenol, respectively. Officially, in the field of acne prevention and therapy, such methods of influencing acne vulgaris as dermatocosmetics and corneo-or enzyme therapy are not used. The use of local and systemic pre- and probiotics for the treatment of acne has not been introduced. This reveals a connection between the development of acne and the intestinal microbiome. The use of local antiandrogens and insulin-like growth factor 1 inhibitors to control sebum production, as well as selective retinoic acid receptor agonists with a better safety profile compared to retinoid therapy for acne, may be promising for the prevention and treatment of acne in adolescents. Findings. Organization of effective treatment of acne in adolescents should include their clear instructions and correction of dietary habits. Prevention of acne today is practically not organized in the field of medical services.
Organizational aspects of home-based telerehabilitation of post-stroke patients.
Authors:   Research Institute for Healthcare Organization and Medical Management of Moscow Healthcare Department, Nikolaev V. A. ,   Pirogov Russian National Research Medical University
Published: May 2024

Restoring neurological functions after a stroke is one of the main medical and social problems of the 21st century. Telemedicine technologies increase the accessibility and coverage of medical care for patients living remotely from medical organizations, with limited mobility, and also during periods of pandemics. However, to date there are no methodological recommendations for making management decisions on organizing home telerehabilitation for patients who have suffered a stroke. This is due to the comparative novelty of technologies and insufficient knowledge of clinical studies, absence or lack of managerial experience. Therefore, the purpose of this article – develop a methodological framework for drawing up methodological recommendations when making management decisions on organizing home telerehabilitation after a stroke, which is a relevant area in the context of the digital transformation of healthcare. Materials and methods. The study was conducted using analytical methods and information retrieval. Results. Matrices have been developed to assess the readiness of the patient and the medical organization to conduct personalized telerehabilitation. A management decision-making scheme is proposed to assess the possibility of organizing telemedicine rehabilitation of a post-stroke patient at home. Findings. The results of the study may be useful to healthcare organizers and become the basis for the development of methodological recommendations when making management decisions on organizing home telerehabilitation for patients of the relevant profile.
Medical and demographic indicators of the rural population over working age in the Republic of Tatarstan.
Authors:   Federal State Budgetary Institution “National Research Institute of Public Health named after N. A. Semashko", Bakirova E. A. , Kalininskaya A. A. ,   Federal State Budgetary Institution “National Research Institute of Public Health named after N. A. Semashko",   State budgetary institution of the city of Moscow “Research Institute of Healthcare Organization and Medical Management of the Moscow Health Department”, Shlyafer S. I. ,   Federal State Budgetary Institution “Central Research Institute for Organization and Informatization of Health Care” of the Ministry of Health of the Russian Federation, Smirnov A. A. ,   Federal State Budgetary Institution “National Research Institute of Public Health named after N. A. Semashko"
Published: May 2024

Demographic aging of the population is especially pronounced in rural areas and has regional differences. Purpose of the study: based on the analysis of medical and demographic indicators of mortality and morbidity of the rural population over working age in the Republic of Tatarstan (RT), to develop proposals for the health of rural residents. Methods and materials: analytical, statistical, Rosstat data and statistical materials from the Federal State Budgetary Institution “TsNIIOIZ” of the Russian Ministry of Health (2019–2022). Results. During the years of pension reform (2019–2023), the number of rural population in the Republic of Tatarstan increased slightly – from 922,3 to 930,3 thousand (0,9%), while the share of the rural population over working age decreased from 28,6 up to 27,5% (in the Russian Federation the figure is lower – 25,5%). The mortality rates of the rural population in the Republic of Tatarstan were significantly higher for all years of analysis: in 2013 they were 15,5‰ for the rural population, 11,0 for the urban population. During the years of COVID‑19, mortality rates increased and amounted to 18,9‰ for the rural population in 2021, 14,4‰ for the urban population, and decreased in 2022 and amounted to 14.1 and 10,3‰, respectively. The primary morbidity rate of the rural population in the Russian Federation (2022) was 64755,2 per 100 thousand rural population, in the Republic of Tatarstan it was lower – 52598,4‰îî. There is a large difference in the indicators in the constituent entities of the Russian Federation – 13,6 times. The newly identified morbidity in the rural population over working age in the Republic of Tatarstan is lower than 48996,2‰îî than in the entire rural population 52598,4‰îî, while the older population has the highest rates of primary morbidity due to diseases of the circulatory system, diseases of the bones, muscular system and connective tissue, diseases of the genitourinary system, diseases of the nervous system, neoplasms, etc. In this age group, the incidence of COVID‑19 is higher. The results of the study should be taken into account for the development of management decisions at the regional level, as well as when implementing programs for rehabilitation and medical examination of older patients.
Gender Diversity in Orthopaedic Surgery Residencies Does Not Translate to Accreditation Council for Graduate Medical Education–Accredited Fellowships
Authors: Haddad David , Nelson Deborah , Sherman Nathan , Tatusko Megan , DeSilva Gregory
Published: May 2024

Introduction:

Gender representation among orthopaedic surgery applicants and residents has increased over the past two decades. The aims of this study were to evaluate trends of female fellows in ACGME-accredited orthopaedic subspecialties between 2007 and 2021, and to compare the fellowship trends of female representation to those of ACGME-accredited orthopaedic residencies.

Methods:

We conducted a retrospective review of publicly available ACGME-accredited fellowship demographic data from 2007 to 2021. The distribution of genders (male vs. female) across subspecialties and orthopaedic surgery residency programs was compared. Chi-square, Spearman correlation, and logistic regression tests were performed to analyze the relationships between year, gender, and fellowship.

Results:

Chi-square analysis demonstrated a significant relationship between gender and year for orthopaedic residency (p < 0.001), but not for any fellowship. There was a significant negative Spearman correlation between the two variables for hand (r(1844) = −0.06, p = 0.02) and sports medicine (r(2804) = −0.05, p = 0.01) fellowships. The negative Spearman correlation for pediatrics (r(499) = −0.09, p = 0.054) approached but did not reach statistical significance. Logistic regression analysis revealed that, holding year constant and comparing to orthopaedic residency, the odds of male participation increased by 173% (95% CI, 1.8–4.1) in spine, increased by 138% (95% CI, 1.7–3.3) in adult reconstruction, increased by 51% (95% CI, 1.3–1.7) in sports medicine, decreased by 41% (95% CI, 0.5–0.7) in hand, decreased by 36% (95% CI, 0.5–0.9) in foot and ankle, decreased by 48% (95% CI, 0.4–0.7) in musculoskeletal oncology, and decreased by 68% (95% CI, 0.3–0.4) in pediatrics.

Conclusion:

Although the percentage of female orthopaedic residents in ACGME-accredited programs increased significantly from 2007 to 2021, this has not translated to ACGME-accredited fellowship positions. Future research optimizing methods to improve the representation of females in orthopaedic surgery should be considered.

Level of Evidence:

III
Business continuity management, operational resilience, and organizational resilience : commonalities, distinctions, and synthesis
Authors: Galaitsi Stephanie , Elizabeta Elizabeta , Keisler Jeffrey , Gianluca Gianluca , Keenan Jesse , Linkov Igor
Published: May 2024

The concepts of business continuity management, operational resilience, and organizational resilience each refer to actions that businesses and organizations can take in anticipating and responding to disruptions. However, the existing definitions and usages are difficult to differentiate due to overlapping objectives, implementation processes, and outcomes. This article examines definitions and approaches for these three concepts and suggest a framework to operationalize methods and tools relevant to each. These definitions emphasize three dyads: risk versus resilience; organizational processes versus assets; and normal operating conditions versus crisis conditions. Using these dyads to differentiate the concepts of business continuity management, operational resilience, and organizational resilience can support planners in clarifying objectives and identifying which approach will be most beneficial as businesses or organizations plan for and encounter disruptions. This article evaluates these concepts by examining illustrative examples of disruptions and responses.
Resin Cements in Dentistry
Authors:   Department of Restorative Dental Sciences, College of Dentistry, King Faisal University, Al Hasa, Kingdom of Saudi Arabia., Katta Prashanth Kumar
Published: May 2024

Even though the GIC has undergone many advances, its chemistry is fundamentally different from that of modern resin based composite direct filling products, which feature a silica or glass particle filled polymer matrix that enhances repair retention. When the restoration is etched or air abraded after the tooth has been conditioned with an adhesive resin and etched, retention becomes "micromechanical," ensuring the resin cement's high tensile strength. Cementation of the extraoral fabricated restoration is very important for the longevity of the restoration. The bond strength of resin cement to ceramic and fibre post is better than conventional cements. This article discusses about the various types of resin cements and there uses for luting indirect restorations such crowns, veneers, inlays, and onlays, etc.
An Unusual Case of Headache: Joining the Dots in the Emergency Room
Authors:   Trainee, Department of Emergency Medicine, Paras Hospitals, Gurgaon 122002, Haryana, India., Dey Rimy
Published: May 2024

Headache is one of the commonest presenting complaints in the Emergency Room. In the young population with no significant history of any medical condition or trauma, it seldom raises suspicion of an ominous etiology. In this case report we present an unusual case of a young unmarried female presenting to the ED with acute onset headache and vomiting. After initiation of primary treatment, the patient was subjected to MRA and MRV of the brain which was suggestive of thrombosed mid part of Superior Sagittal Sinus, right Sigmoid and right Transverse sinus. On eliciting the SAMPLE history of the patient, the risk factor of polycystic ovarian syndrome and intake of Norethisterone for Abnormal Uterine Bleeding was known. Provisional diagnosis of Norethisterone induced Cerebral Venous Sinus Thrombosis was considered and patient was initiated on treatment with Enoxaparin (Low Molecular weight Heparin) followed by long term NOAC and lifetime avoidance of Norethisterone and other prothrombotic drugs.
Banana Leaf for Management of Toxic Epidermal Necrolysis
Authors:   Department of Emergency Medicine, King George's Medical University, Lucknow 226003, Uttar Pradesh, India., Mani Utsav Anand , Abbas Haider , Kumar Mukesh , Gupta Pranay ,   Department of Emergency Medicine, King George's Medical University, Lucknow 226003, Uttar Pradesh, India.
Published: May 2024

ntroduction: Toxic Epidermal Necrolysis (TEN) and Steven Johnson Syndrome (SJS) are severe mucocutaneous reactions. Managing these conditions is challenging, especially in resource-limited settings. This case report introduces a cost-effective treatment approach in a developing country context. Case Report: A patient in India with TEN/SJS, likely due to homeopathic medication, was treated using autoclaved banana leaves. This innovative method provided pain relief and accelerated wound healing, demonstrating its potential as an alternative treatment. Conclusion: Utilizing banana leaves for TEN/SJS highlights a novel, economical approach suitable for developing countries. This case underscores the need for further research into such alternatives, especially in regions where standard medical resources are limited or too expensive. Key Messages: This case report discusses the innovative use of banana leaves for managing Toxic Epidermal Necrolysis (TEN) and Steven-Johnson Syndrome (SJS), highlighting its affordability and potential benefits in patient care, especially in developing countries with limited access to conventional treatments.