bluuebunny/crossref_metadata_2025 huggingface dataset:
De la V1 à la V2 de la Cité des dames de Christine de Pizan : étude de quelques révisions linguistiques
Authors: Valentini Andrea
Published: December 2022

This paper analyses two processes at work in Christine de Pizan’s reworking of the first version (V1) of her Book of the City of Ladies to produce a second version (V2). These two processes consist in the elimination of repetitions and the addition of synonyms to create binomials. They show that the author paid great attention to the language of her text when reworking it. They also appear to be typical of the search for a higher style. The fact that Christine de Pizan uses a high style to refer to women is all the more interesting: according to the principle of matching style to content, a high style contributes to the importance of women and thus, ultimately, to the author’s feminist struggle.
Mechanical forces impair antigen discrimination by reducing differences in T‐cell receptor/peptide–MHC off‐rates
Authors: Pettmann Johannes , Awada Lama , Różycki Bartosz , Huhn Anna , Faour Sara , Kutuzov Mikhail , Limozin Laurent , Weikl Thomas R , van der Merwe P Anton , Robert Philippe , Dushek Omer
Published: December 2022

T cells use their T‐cell receptors (TCRs) to discriminate between lower‐affinity self and higher‐affinity foreign peptide major‐histocompatibility‐complexes (pMHCs) based on the TCR/pMHC off‐rate. It is now appreciated that T cells generate mechanical forces during this process but how force impacts the TCR/pMHC off‐rate remains debated. Here, we measured the effect of mechanical force on the off‐rate of multiple TCR/pMHC interactions. Unexpectedly, we found that lower‐affinity TCR/pMHCs with faster solution off‐rates were more resistant to mechanical force (weak slip or catch bonds) than higher‐affinity interactions (strong slip bonds). This was confirmed by molecular dynamics simulations. Consistent with these findings, we show that the best‐characterized catch bond, involving the OT‐I TCR, has a low affinity and an exceptionally fast solution off‐rate. Our findings imply that reducing forces on the TCR/pMHC interaction improves antigen discrimination, and we suggest a role for the adhesion receptors CD2 and LFA‐1 in force‐shielding the TCR/pMHC interaction.
Soviet Lithuanian New Year Greeting Card: Semiotics of Recto
Authors: Atminytė Evelina
Published: December 2022

The article discusses the semiotics of greeting card with focus on the discursive configuration of the recto side. The aim is twofold: to examine the possible ways image and verbal text are combined and identify the meaning produced by its different configurations. Soviet Lithuanian New Year greeting cards (dated from the late 1950s to 1989) are analyzed to accomplish the study. The methodological approach is compound. The guidelines of Greimasian theory of semiotics and Tartu-Moscow semiotic school as well as the ideas of Jacques Fontanille and Jean-Marie Floch are used to perform the study. 

The discourse analysis revealed that when placed on the recto side greeting text both anchors the content of the image and acts as a performative utterance. Depending on the specific configuration of the recto side and the material aspects of a greeting card, the role of enunciator can be subjected either to the artist or image figures. However, in some cases the performative function becomes secondary. For example, when playfulness established by the interrelation of image and verbal text is given priority over the greeting act.
The Accusation of Dohnányi: The Legal Procedure in Hungary, 1945–1946
Authors: Kusz Veronika
Published: December 2022

Ernő Dohnányi, the world-renowned musician, was almost entirely forgotten during the decades between his emigration in 1944 and the change of political regime in Hungary: his name actually disappeared from public cultural knowledge. Though there may have been several explanations for the ignorance, it is not an exaggeration to state that the main reasons behind the tragic gap in his posthumous reception are of a political nature. It is widely known nowadays that during the settlements after World War II, Dohnányi – in his absence – was charged with intellectual collaboration with the Hungarian far right-wing regime. According to the present state of research, the charges were finally withdrawn as they were mostly ungrounded. Yet, the formerly adored artist and central personality in cultural life had become persona non grata for more than 40 years. After the political changes, his oeuvre seemed to be rehabilitated but without a thorough investigation of the charges and their background. This is why political prejudices are currently experienced simultaneously with a total bagatellization of the possible mistakes in his interwar activity. Thus, a systematic research into this subject has become very urgent. This study, which is intended to be a chapter of a full-length monograph on Dohnányi and politics (expected in 2023/24), was founded by the János Bolyai Scholarship of the Hungarian Academy of Sciences, and is one of the very first publications of this project in English. It aims to give a thorough description of the first two years of the official proceeding against Dohnányi at the different investigative levels such as the justificatory committees, public prosecutor, and government ministry.
Reconstruyendo los procesos de reproducción de monumentos: la huella sobre los grandes formatos del siglo XIX
Authors: Lasunción-Ascanio Montserrat
Published: December 2022

La realización de réplicas mediante moldes no supuso una novedad en el siglo XIX pero por varios motivos, y en especial, la creación de los museos públicos, el uso de los vaciados como objeto museístico se disparó por todo el mundo, gracias al empleo de nuevos materiales y técnicas perfeccionadas. Este artículo aborda algunas cuestiones referentes a los procesos de moldeo sobre monumentos, partiendo de nueva información localizada en la documentación archivística relativa a los mismos. Una cadena en la que los solicitantes, los propietarios de los originales y la gestión de las operaciones se ponen en relación directa con el estado de conservación de los monumentos y el rol de la réplica en la preservación del patrimonio monumental actual.
Civilia: Utopia in the Age of Photomechanical Reproduction. Architectural (Photo)copy as (Re)invention
Authors: Lus-Arana Luis-Miguel , Parnell Stephen
Published: December 2022

In June 1971, The Architectural Review featured the culmination of Townscape, a campaign that the issue’s author, as well as the magazine’s editor and owner, Hubert de Cronin Hastings, promoted for decades. Civilia, The End of Suburban Man was a monograph that described a fictional English New Town, illustrated through an extensive collection of views of its urban scene made from hundreds of photographs of buildings, many of which had appeared in the pages of the different publications of the Architectural Press in the preceding decades. Civilia did not manage to provoke the debate that Hastings desired, remaining a mere curiosity wrapped in a spectacular visual apparatus that has hardly been analyzed. However, the striking vedute of Civilia hide an elaborate exercise in the generation of architectural form. Its collages include an extensive catalog of architectural strategies and forms in which buildings are appropriated through their photographic images, to engender a series of distorted copies, new architectural personae which simultaneously alter our perception of the originals by either enveloping them in new narratives or revealing their hidden qualities.
Synergistic effect of novel HDAC inhibitors with chemotherapy drugs in acute myeloid leukemia
Authors:   , Giménez Naroa
Published: December 2022

Acute myeloid leukemia (AML) is a highly heterogeneous malignant disease characterized by uncontrolled proliferation, differentiation arrest and accumulation of immature myeloid progenitors. Despite recent developments and the approval of new therapeutic agents in the last few years, outcome remains poor for most patients, particularly in elderly patients, being an urgent unmet need for therapeutic improvements. After rigorous studies, our group identified and characterized two novel HDACi (histone deacetylases inhibitors), CM-444 and CM-1758, exhibiting higher capacity to promote in vitro and in vivo myeloid differentiation in all subtypes of AML at low non-cytotoxic doses in comparison with commercial HDACi. The acetylome analysis after CM-444 and CM-1758 treatment showed the modulation of a specific non-histone protein acetylation pattern in AML cells. CM-444 and CM-1758 led to acetylation of bromodomain proteins (BRDs), especially BRD4 and BRD1, and other non-histone proteins involved in the enhancer-promoter chromatin regulatory complex. This is essential to enhance the expression of key transcription factors that induce myeloid differentiation and play a very important role in the differentiation therapy exerted by CM-444 or CM-1758 in AML cells. Interestingly, the complete transcriptome analysis after CM-444 and CM-1758 treatment showed changes in genes implicated in chemo-sensitivity, suggesting that CM-444 and CM-1758 could also enhance the efficacy of conventional chemotherapy for AML treatment. CM-444 and CM-1758 led to promising synergistic effect in combination with Doxorubicin and 5-AZA agents in vitro. Moreover, a slight improvement on Doxorubicin treatment was obtained in those AML cells that were previously induced to overexpress the chemo-sensitive gene ALOX5. Proposing that ALOX5 overexpression induced by CM-444 and CM-1758 is one of the possible molecular mechanisms underlying the synergistic effect previously obtained between HDACi (CM-444 and CM-1758) and Doxorubicin or 5-AZA. In summary, on the one hand these new epigenetic compounds might be an effective differentiation-based therapy with a novel mechanism to be tested in AML. And on the other hand, these novels HDACi could also be combined with therapeutic agents to improve their therapeutic effect, in part due to chemo-sensitive gene expression induced by the compounds themselves.
Examples and outline of certain modifications in isentropic analysis
Authors: Montgomery Raymond B. , Spilhaus Athelstan Fred
Published: December 2022

Isentropic analysis in this country originated with a particular purpose in view, namely as a means of using moisture distribution to determine flow patterns in the atmosphere It revealed, very successfully, certain theoretically anticipated patterns. Subsequently it has come into general use in connection with upper-air analysis but for the most part its application is dominated by the original particular purpose. A rather different approach is to use isentropic analysis in a more purely descriptive fashion as the principal tool for upper-air analysis. This demands that an isentropic chart represent synoptically as much useful information as possible and that all phases of its preparation receive due care.
Oceanographic observations from the Semmes : Jan. 14-Feb. 14, 1941
Authors: Iselin Columbus O'Donnell
Published: December 2022

Oceanographic Observations from the SEMMES Jan. 14-Feb. 14, 1941 On a recent cruise through the West Indies a program of oceanographic observations was carried out on board the experimental sound ship, the U.S.S. SEMMES, in conjunction with the submarine, TRITON. This work which began on January 14 at New London, Conn. and ended on February 14 at Key West, Fla. included a week of operations with the East Coast Sound School out of Key West. The bathythermograph, an instrument for measuring the sea water temperature continuously from the surface down to 75 fathoms, was used for oceanographic observations.
A slide rule for computing supersonic ray diagrams from bathythermograph data
Authors:   Woods Hole Oceanographic Institution
Published: December 2022

This report, and the accompanying slide rule were prepared by the Woods Hole Oceanographic Institution for the National Defense Research Committee.
Early echocardiographic alterations in cancer patients during chemotherapy
Authors: Fashafsha Z. Z.A. , Chomakhidze P. Sh. , Mesitskaya D. F. , Suvorov A. Yu. , Sekacheva M. I. , Poddubskaya E. V. , Tyukanova E. S. , Sankova M. V. , Ozova M. A. , Levina V. D. , Andreev D. А. , Kopylov F. Yu.
Published: December 2022

Aim. To evaluate the early manifestation of cardiotoxicity after the first course of multiagent chemotherapy (MAC) using echocardiography with an assessment of the left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS).

Material and methods. The study included 49 cancer patients with elective MAC.

Results. After the first administration of a therapeutic dose of chemotherapy, a decrease in LVEF ≥10 and GLS >15 was demonstrated in more than 6,1% of patients, as well as a subclinical decrease in LVEF ≥5% in 22,4% and a decrease in GLS ≥12% in 24,5%.

Conclusion. In cancer patients, after the first course of chemotherapy, GLS dynamics should be assessed during echocardiography as a marker of myocardial dysfunction.
Risk factors for cardiovascular diseases in patients received complex treatment for cranial and craniospinal tumors in childhood
Authors: Novikova A. I. , Poltavskaya M. G. , Pavlova M. G. , Chomakhidze P. Sh. , Sotnikov V. M. , Potemkina N. A. , Bykova A. A. , Salpagarova Z. K. , Fashafsha Z. Z. , Soboleva T. V. , Andreeva O. V. , Zheludkova O. G. , Andreev D. А.
Published: December 2022

Aim. To study the traditional risk factors for cardiovascular disease (CVD), indicators of endothelial function and exercise tolerance in patients received complex treatment for cranial and craniospinal tumors in childhood, including radiation therapy.

Material and methods. We compared examination data of 48 patients who underwent treatment for brain tumors using cranial and craniospinal irradiation in childhood (mean age, 21,7±4,3 years, mean period after the end of treatment, 6,9±5,4 years), and 20 healthy volunteers. Examination methods included assessment of lipid profile, vascular stiffness and endothelial function using the Photoplethysmography and occlusion test, cardiopulmonary test, and in patients who underwent craniospinal irradiation, also echocardiography and duplex ultrasound of extracranial arteries.

Results. Compared to healthy individuals, patients after a brain tumor were found to have lower blood pressure, higher heart rate (HR), significantly lower exercise performance (peak oxygen consumption, 19,8±6,4 ml×min-1×kg vs 30,3±5,8 ml×min-1×kg, p<0,0001) and a higher prevalence of dyslipidemia (56% vs 5%, p<0,0001), as well as an increase in the augmentation index, indicating higher stiffness of large vessels (-7,3±16,3 vs -20,3±7,9, p=0,001), and a trend towards a decrease in the occlusion index (p=0,051). Echocardiography and duplex ultrasound revealed no radiation-associated abnormalities.

Conclusion. Determining the mechanisms and prognostic significance of the identified risk factors for CVD (dyslipidemia, decreased exercise tolerance, increased heart rate and vascular stiffness) in this category of patients requires further research. Regular monitoring of risk factors, primarily the lipid profile, and the use of preventive measures for individuals with an increased risk of CVD should be recommended.
Chest pain: a review of current principles and approaches to first aid
Authors: Birkun A. A. , Dezhurny L. I.
Published: December 2022

Chest pain is a typical manifestation of acute myocardial ischemia. The likelihood of death in myocardial infarction increases significantly as the pain to hospital times increase, Therefore, timely recognition of this symptom as a possible manifestation of ischemia, calling an ambulance and first aid before the arrival of ambulance team can play a vital role in saving lives. A review of modern principles and rules for first aid to patients with chest pain is presented, based on an analysis of international and national guidelines. We demonstrated the need and identified directions for improving the organization of first aid in this condition in Russia, as well as analyzed approaches to remote questioning and provision of instructions on first aid for chest pain by ambulance dispatchers by phone, Based on the comparative analysis of dispatcher guidelines and protocols and international guidelines on first aid for chest pain, a universal Russian-language dispatcher algorithm for remote care for chest pain has been developed, which is proposed for discussion and further testing as a potential component of a unified domestic dispatcher support program for first aid.
High-sensitivity troponin I as a predictor of left ventricular dysfunction in the use of cardiotoxic anticancer agents for breast cancer in patients with predominantly low and moderate risk of cardiotoxicity
Authors: Levina V. D. , Poltavskaya M. G. , Chomakhidze P. Sh. , Meshcheryakov A. A. , Bolotina L. V. , Deshkina T. I. , Valiulina D. S. , Gerasimov A. N. , Andreeva O. V. , Shmeleva A. A. , Fashafsha Z.Z.A. , Levshina A. R. , Sedov V. P.
Published: December 2022

Aim. To study the significance of monitoring high-sensitivity troponin I (hs-cTnI) for predicting anthracycline-induced left ventricular (LV) dysfunction in the treatment of breast cancer in patients with moderate and low risk of cardiotoxicity (CT).

Material and methods. The study involved 49 patients with breast cancer aged 50±10 years who underwent neoadjuvant or adjuvant chemotherapy, which included doxorubicin at a course dose of 60 mg/m2 and an average cumulative dose of 251±60 mg/m2. The level of hs-cTnI was determined by an ultrasensitive method before the start of chemotherapy, after each course of anthracyclines and in 18 patients before the administration of anthracyclines. The level of hscTnI >0,017 ng/ml was considered elevated. Echocardiography was performed before the start of chemotherapy, after the end of anthracycline therapy, and every 3 months for 12 months thereafter. CT was defined as a decrease in LV ejection fraction (EF) by ≥10% to <53%.

Results. CT risk before chemotherapy was considered low and moderate in 96% of patients. An increase in hs-сTnI was detected ≥1 times in 56,8% of patients: before chemotherapy — in 13,5%, after 1 and 2 courses of anthracycline therapy — in 13,9%, after 3, 4, 5 and 6 courses — in 44%, 62%, 71% and 66% of patients, respectively. The levels of hs-cTnI before and after administration of anthracyclines did not differ significantly. The development of LV dysfunction was observed in 16,3% of patients. There were following prognostic significance of an increase in hs-cTnI at any time of chemotherapy for a decrease in LV EF: sensitivity — 87,5%, specificity — 50%, the positive predictive value — 28%, the negative predictive value — 94,7%. The closest relationship was noted between CT and hs-cTnI value before the start of chemotherapy (β=0,45, p=0,005) and after the 3rd course of anthracycline therapy (β=0,56, p=0,002).

Conclusion. An increase in hs-cTnI level before and during anthracycline thera py in patients with a low risk of cardiotoxicity has a prognostic value in relation to the development of left ventricular dysfunction. Hs-cTnI assessment should be performed before the start of therapy, and then starting from the 3rd course of anthracycline therapy in all patients, regardless of the risk of cardiotoxicity.
Relationship between the degree of myocardial damage according to contrast-enhanced cardiac magnetic resonance imaging and laboratory data in patients with acute myocardial infarction
Authors: Mochula O. V. , Sulejmanova A. S. , Sukhareva A. E. , Ryabov V. V. , Zavadovsky K. V.
Published: December 2022

Aim. To evaluate the information value of a complex of clinical and biochemical parameters of myocardial damage in predicting the development of transmural myocardial damage according to magnetic resonance imaging (MRI) in patients with acute myocardial infarction (AMI).

Material and methods. The study included patients admitted to the emergency cardiology department with acute coronary syndrome. All patients underwent invasive coronary angiography, laboratory tests, and dynamic determination of cardiac biomarkers. In the interval of 6,1±4 days from admission to the hospital, patients underwent contrast-enhanced cardiac MRI. According to the pattern of delayed contrast enhancement, patients were divided into two groups: with a transmural and subendocardial pattern.

Results. The mean age of patients was 62,5±10,5 years, while 27 (71,1%) had ST-segment elevation AMI. Among the risk factors for coronary artery disease, dyslipidemia (89,5%), hypertension (68,4%), and smoking (57,9%) were the most common. Creatine phosphokinase-MB (CPK-MB), serum high-sensitivity cardiac troponin I (cTnI) and C-reactive protein (CRP) values after 24 h were significantly higher in patients with transmural hyperenhancement. Moderate positive relationship was found between the global size of left ventricular (LV) damage according to MRI data and the levels of CPK-MB after 24 h and 4 days, as well as with CRP after 24 h, 4 and 7 days, and cTnI level after 24 h and 4 days. In the group of patients with transmural pattern, the global size of LV damage was significantly higher. Patients of this group were characterized by higher prevalence of microvascular obstruction. In a univariate regression analysis, there were following significant predictors of transmural myocardial damage: CPK-MB after 4 days (p=0,023) and ST segment elevation (p=0,029). Multivariate regression analysis showed that the only independent predictor of transmural myocardial damage was an increase in CPKMB after 4 days (p=0,023).

Conclusion. An independent predictor of LV transmural damage in AMI was an elevated level of CPK-MB after 4 days. However, this laboratory marker had unsatisfactory information completeness and predictive quality. In this regard, cardiac MRI in patients with AMI, compared with the standard clinical assessment, can be considered preferable for assessing the depth of myocardial damage, risk stratification, and prognosis.
Prevalence of frailty syndrome in Brazil: a systematic review
Authors: Fabrício Daiene de Morais , Luchesi Bruna Moretti , Alexandre Tiago da Silva , Chagas Marcos Hortes Nisihara
Published: December 2022

Abstract Background The population is aging rapidly, which leads to an increased prevalence of frailty syndrome. A large number of investigations on the subject have been conducted in Brazil, but no systematic review of prevalence studies involving the Brazilian population has been carried out considering the characteristics of the sample and the evaluation methods used. Objective To develop a systematic review of studies that assess the prevalence of frailty syndrome in Brazil, analyzing the clinical and demographic characteristics of the samples and the methods used for the diagnosis of the syndrome. Method The searches were carried out in the PubMed, SciELO and Web of Science databases using the following keywords: (prevalence or epidemiology) and frailty and Brazil. Results Forty-seven articles met the eligibility criteria and were included in the review. The prevalence of frailty ranged from 3.85% to 74.1%, depending on the assessment instrument used, context, region and population studied. Conclusion The prevalence data are discrepant, and the standardization of screening methods for the frailty syndrome could facilitate the comparison between studies, in order to maximize and create intervention strategies, especially in a country with cultural diversity and regional disparities, such as Brazil
Prevalence of kinesiophobia and catastrophizing in patients with temporomandibular disorders
Authors: Silva Luciana Micaelly Costa Pessoa , Rodrigues Bruna Alves , Lucena Hiênio Ítalo da Silva , Morais Edna Pereira Gomes de , Rocha Ana Carolina , Lucena Luciana Barbosa Sousa de , Alves Giorvan Anderson dos Santos , Benevides Silvia Damasceno
Published: December 2022

ABSTRACT Purpose: to identify the frequency and levels of kinesiophobia and catastrophizing in patients with temporomandibular disorders who had been submitted to speech-language-hearing therapy. Methods: the sample comprised patients with myogenous (predominantly) and mixed temporomandibular disorders in the study group and healthy individuals in the control group. The instruments used were the Diagnostic Criteria for Temporomandibular Disorders, Tampa Scale for Kinesiophobia, and Pain Catastrophizing Scale. Statistical analyses were performed with the Mann-Whitney test (to compare the means on each scale between the groups) and the Spearman’s correlation coefficient test (to analyze the correlation between the scales in each group and its significance). Results: the study group had a higher pain catastrophizing index than the control group. Likewise, the study group had greater kinesiophobia positive indices, whereas the control group had lower ones. A moderate positive correlation was also identified between kinesiophobia and catastrophizing in the study group. Conclusion: patients presented with temporomandibular disorders have higher levels of kinesiophobia and catastrophizing than subjects not diagnosed with the disorder.
Parasitism of Tetrastichus howardi (Ollif, 1893) (Hymenoptera: Eulophidae) on Chrysodeixis includens (Walker, [1858]) (Lepidoptera: Noctuidae) pupae at different ages
Authors: Barbosa Marcelo Sousa , Guerra Mariana Santana , Pereira Fabricio Fagundes , Silva Otávio Henrique Medina da , Silva Ivana Fernandes da
Published: December 2022

ABSTRACT Tetrastichus howardi (Olliff, 1893) (Hymenoptera: Eulophidae) is an adult parasitoid of lepidopteran pests, and the age of the host has a strong influence on its reproduction. This study aimed to evaluate the biological characteristics of T. howardi reared on different aged pupae of Chrysodeixis includens (Walker, [1858]) (Lepidoptera: Noctuidae). For that, pupae with 24, 48, 72, 96, 120, 144 or 168 h of age were exposed to parasitism. The experimental design was completely randomized, with seven treatments (pupal age) and ten replications, with each replication consisting of five pupae individualized with one female parasitoid at the respective ages. Tetrastichus howardi parasitized and emerged in pupae of all the evaluated ages. The duration of the cycle (egg-adult) in days, number of parasitoids that emerged per pupa (progeny), progeny per female, sex ratio of the parasitoid and longevity of adults were similar. This is the first record of T. howardi reproducing in C. includens pupae under laboratory conditions. The highest parasitism and development of T. howardi was obtained in 24-to 96-hour-old pupae of C. includens, indicating that this age range is more favorable to rear this parasitoid under laboratory conditions.
Inoculation and co-inoculation with multifunctional rhizobacteria for the initial development of soybean
Authors: Silva Mariana Aguiar , Cruz Dennis Ricardo Cabral , Frasca Laylla Luanna de Mello , Filippi Marta Cristina Corsi de , Ferreira Amanda Lopes , Nascente Adriano Stephan
Published: December 2022

ABSTRACT Soybean inoculation and co-inoculation with multifunctional rhizobacteria is a sustainable alternative that may contribute to plant growth and increased agricultural production, making the product more competitive, as well as reducing costs for the producer. This study aimed to evaluate the effect of inoculation and co-inoculation with multifunctional Serratia sp. and Bacillus sp. rhizobacteria on the early development of soybean. A completely randomized experimental design was used, with four treatments and ten replicates, totaling 40 experimental plots. The treatments consisted of the microbiolization of soybean seeds and a control treatment: BRM 32114 (Serratia sp.) isolate; BRM 63573 (Bacillus sp.) isolate (formerly named 1301); co-inoculation with BRM 32114 + BRM 63573; and control (without microbiolization). BRM 32114 and BRM 63753, both isolated and combined, were eficient to improve the initial development of soybean seedlings, providing significant effects for most of the analyzed variables (length, total surface, root volume and root, shoot and total biomass), when compared to the control treatment.
Propuesta metodológica para el análisis de tiestos pintados Guaraní. El caso de la colección de la Isla Martín García del Museo de La Plata
Authors: Maravilla María Laura , Torino Rocio
Published: December 2022

Resumen Para la arqueología, la cerámica ha sido el principal elemento de la cultura material utilizado para identificar la presencia guaraní. La alfarería muestra un modo de hacer común compartido por casi dos milenios y que, se haya presente en sitios distribuidos por Argentina, Brasil y Uruguay. Sin embargo, las piezas cerámicas casi nunca son encontradas enteras. En este sentido, en el presente trabajo se desarrolla una propuesta metodológica que incluye el análisis tecnomorfológico y estilístico de los tiestos pintados procedentes de la Colección arqueológica isla Martin García depositada en la División Arqueología del Museo de La Plata (Argentina). El objetivo fue identificar la organización espacial, cromática y formal de los grafismos pintados y evaluar su relación con las formas de los recipientes cerámicos. Se segregaron los grafismos en unidades analíticas en función de ciertos criterios ajustados a los fragmentos cerámicos. Se identificaron dos tipos de patrones en los diseños, lo que permitió pensarlos de acuerdo a diferentes estructuras lógicas que ordenan la articulación de los motivos en relación a la morfología y al sector del recipiente en el que se disponen, así como a su forma global.
A utilização do ocre na pré-história da Serra da Capivara, Piauí, Brasil
Authors: Cisneiros Daniela , Tavares Bruno , Costa Hércules
Published: December 2022

Resumo O ocre constitui-se em uma matéria-prima que, por sua natureza mineral, resistência e estabilidade, foi conservada em contextos arqueológicos desde o Pleistoceno superior, permitindo aos arqueólogos observarem sua exploração em situações funcionais e simbólicas distintas. O presente artigo pretende abordar a utilização do ocre na pré-história da Área Arqueológica Serra da Capivara, Piauí, em contextos funerários e rupestres. Discute-se aqui também o interesse por esse tipo de material ao longo do desenvolvimento da Arqueologia, as diferenças mineralógicas e as técnicas físico-químicas, para caracterizar sua composição. Pesquisas realizadas na Serra da Capivara têm apontado a larga utilização do ocre ao longo da pré-história. Esses vestígios, obtidos a partir de escavações e contextos arqueológicos distintos, podem ser evidenciados em diferentes estágios da cadeia operatória. A presença de ocre nos enterramentos ocorre nos seguintes contextos e processos: pigmentos à base de ocre aplicado direta e indiretamente sobre os ossos, artefatos e ecofatos pigmentados e ocres com e sem marcas de utilização. Nas pinturas rupestres, aparecem sob dois tipos de técnica de aplicação: líquida/pastosa e sólida. O ocre arqueológico evidenciado nessa área encontra-se homogêneo e livre de incrustações, demostrando a seleção prévia do material a ser utilizado.
Nietzsche contra a domesticação das instituições de ensino
Authors: Ribeiro Marco Antonio Sabatini , Carvalho Alexandre Filordi de
Published: December 2022

Resumo: A filosofia nietzschiana se desdobra, a todo tempo, em denunciar que as escolas e universidades da Alemanha moderna serviam, majoritariamente, para domesticar as forças humanas em prol dos valores administrados pelo Estado. Considerando tal horizonte, este artigo investiga o fundo analítico da crítica nietzschiana à educação (Ersiehung) de seu tempo para mostrar a tensão necessária que a formação humana (Bildung) emerge no arcabouço de sua filosofia como cultivo de novos valores. Para tanto, será preciso mostrar que outro nível de disciplina, ao mesmo tempo causa e efeito de uma experiência formativa singular e própria, há de ser deflagrada como potência criativa de e para outros valores existenciais.
The mechanical testing of a novel interlocking forearm nail
Authors: Pretorius H , Burger M , Ferreira N
Published: December 2022

BACKGROUND: Mechanical testing of newly designed implants provides valuable insight into their mechanical properties. This provides surgeons with information about implant choice for the treatment of fractures and the effect of the implant's mechanical properties on fracture healing METHODS: A novel interlocking forearm nail was subjected to standardised mechanical testing according to the Standard Specification and Test Methods for Intramedullary Fixation Devices (ATSM 126416), using static and dynamic four-point bending and static torsion (ASTM STP 588). Three nails were used for the static bending and torsion and nine for the dynamic bending tests. All nails were catalogued, numbered and photographed before testing RESULTS: The mechanical testing results showed a mean force yield (Fy) of 566 ± 20 N, a moment of yield (My) 10.75 ± 0.37 Nm, a stiffness of 67.10 ± 2 N/mm and structural stiffness of 1.53 ± 0.50 m2. The torsional stiffness of the nail was 0.088 ± 0.002 Nm/°. The four-point dynamic bending test showed a fatigue strength of 5.23 Nm. This value was determined using the semi-log moment/ number of cycles (M-N) diagram and showed a 50% failure at a million cycles. If the moment were reduced to 4.4 Nm, mathematically, the survival rate would improve to 90% CONCLUSION: The results from this mechanical testing show that this novel intramedullary forearm nail can resist mechanical forces experienced during fracture healing and could potentially be used in future clinical studies Level of evidence: Level 4
COMPARATIVE STUDY OF THE RECOMBINANT ACTIVITY EFFECT AT THE GRAIN BOUNDARIES IN SILICON SOLAR CELLS
Authors: Djellil Bilal , Merabet Souad , Bouridah Hachemi
Published: December 2022

This work studies the effect of carrier trapping and the recombination activity at the grain boundaries in the p-layer of polysilicon solar cells with respect to the deposition temperature. The dependence of the grain size on the deposition temperature was studied in different samples of boron-doped low-pressure chemical vapor deposition (LPCVD) silicon deposits, conducted in a horizontal low-pressure atmospheric pressure reactor where the temperature varied over a range from 520 °C to about 605 °C. The obtained results show clear evidence of dependence on effective changes in the trapping effect as a function of the trapping density states, the doping level and the thickness dimension of the deposited layer.
COMPARATIVE STUDY FOR BIM-BASED LEED INDUSTRIAL BUILDING AND NON-LEED INDUSTRIAL BUILDING
Authors: SEYİS Senem
Published: December 2022

This study intends to do architectural and structural designs of a sustainable industrial building using BIM and LEED as well as compare the LEED industrial building and non-LEED industrial building. In this scope, the additional costs related to water and energy efficient systems were analyzed to calculate the respective break-even points. Literature review and case study were performed to achieve the research objective. In the case study, a reinforced concrete industrial building was designed via Autodesk Revit 2021 considering the selected sustainability criteria under the LEED v4.1 BD+C for New Construction rating system. The LEED industrial building can fulfill 31 credits and 8 prerequisites which allow to obtain 73 points and LEED Gold certificate. The initial cost of LEED industrial building is 154.222.607 TL while the initial cost of non-LEED industrial building is 139.080.060 TL. Break-even point for the cost of energy-efficient systems utilized in the LEED industrial building is 14 years. Break-even point for the cost of water-efficient systems utilized in the LEED industrial building is 8 years. Results contribute to the architecture, engineering and construction industry and literature by providing constructive information about the design requirements and energy, water, and cost performance of the LEED industrial buildings.
SÜRDÜRÜLEBİLİR ULAŞIM PLANLAMASI İÇİN ŞEHİR İÇİ OTOBÜS HATLARINDA SEFER ÇİZELGELEME OPTİMİZASYONU
Authors: POLAT Ulviye , SAĞBAŞ Aysun , DERMENCİ Melike Selen
Published: December 2022

Ülkemizde ve dünyada nüfusun sürekli artması ile birlikte, toplu taşıma ve ulaşım sistemlerinin planlanması ve bu süreçte yaşanan sorunların çözümü; çevresel duyarlılık, ekonomik ve toplumsal fayda açısından çok büyük önem arz etmektedir. Şehir içi toplu taşıma sistemlerinde sefer sıklıklarının ve sayılarının optimum seviyesinin belirlenmesi; maliyet, çevresel etki ve toplumsal refah ekseninde toplu taşımanın en önemli sorunlarından olup, şehirde yaşayan tüm bireyler için kritik bir konudur. Bu çalışmada; şehir içi toplu taşıma (otobüs) sistemlerinin verimli ve sürdürülebilir olarak planlanması amacıyla; Tekirdağ/Çorlu Belediyesi toplu taşıma ulaşım sistemlerinin günlük sefer sayılarının, sefer sıklıklarının ve yolcu taşıma kapasitelerinin mevcut durumu incelenerek sefer sayısı optimizasyonu yapılmıştır. Bu amaçla ulaşım yönetim sistemi verileri kullanılmış ve günlük sefer sayısı optimizasyonu için doğrusal hedef programlama modeli geliştirilmiştir. Model, LINGO paket programı yardımıyla çözülerek, gün bazında optimum sefer sayısı belirlenmiştir. Çalışmada seçilen pilot otobüs hattı için detaylı analizler gerçekleştirilmiştir. Mevcut durum sistem tasarımı ve optimum sistem tasarımı sonuçları karşılaştırmalı olarak değerlendirilmiş olup fayda maliyet analizi yapılmıştır.
A New Perspective on the Relationship Between the Construction Industry Performance and The Economy Outcome- A Literature Review
Authors:   School of Civil Engineering, Faculty of Engineering, University of Technology Malaysia, Mohammed Hatem Zaid , A. Kassem Mukhtar ,   Department of Quantity Surveying, Faculty of Built Environment & Surveying, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia, Ali Kherun Nita ,   Department of Quantity Surveying, Faculty of Built Environment & Surveying, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia, Khoiry Muhamad Azry ,   Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia
Published: December 2022

The attempts to analyze the relationship between the construction industry and economic growth have integrated many different methods. The process has become to be perceived as “construction economics” analysis. It is conceptualized as a procedure where construction industries outcomes implement increasingly more relevant for nation’s development benefits throughout mostly economic interdependencies that are emphasized as financial sources. Concurring with the present-day standards for affirming an industry, in considerably most facets of analysis result interpreted on a solely economic aspect which is not a conspicuous and significant indicator for construction industry initiates through its resolution outcome. Whereas proceed competently and developed directions from scholars or experts are the determinants of success that emerge due to reviews of relevant practical and research inferences. Literature for analysis on output in the construction industry within the economics aspect is further inscribed in detail. Consequently, relocating the ideology used to examine construction activates implications on development augmentation and shifts the schemes for classifying construction output in the numerous conservative analytic techniques towards more functional delineation. Considering and optimize more relevant details in the systematic process of quantifying the construction value analysis will implicate a reflected actual and detailed results of industrial or enterprise entities on both theoretical and empirical perception for construction economics.
Investigation on Prestressed Concrete Sleeper (PCS) Subjected to Dynamic Loading on Site and Experimental Works.
Authors:   Researcher, Permanent Way Infrastructure Research Group, School of Civil Engineering, College of Engineering, Universiti Teknologi  MARA, Cawangan Pulau Pinang,Kampus Permatang Pauh, 13500 Permatang Pauh, Pulau Pinang, Malaysia, Rozli Mohd Ikmal Fazlan , Che Mohd Jamaludin Che Mohd Hilmi Safiuddin ,   Researcher, Permanent Way Infrastructure Research Group, School of Civil Engineering, College of Engineering, Universiti Teknologi  MARA, Cawangan Pulau Pinang,Kampus Permatang Pauh, 13500 Permatang Pauh, Pulau Pinang, Malaysia, Ahmad Juhaizad ,   Senior Lecturer, School of Civil Engineering, College of Engineering, Universiti Teknologi MARA, Cawangan Pulau Pinang,Kampus  Permatang Pauh, 13500 Permatang Pauh, Pulau Pinang, Malaysia, Abdul Rahman Abdul Samad ,   Senior Lecturer, School of Civil Engineering, College of Engineering, Universiti Teknologi MARA,Shah Alam, Selangor, Malaysia, Abd. Ghani Kay Dora ,   Senior Lecturer, School of Civil Engineering, College of Engineering, Universiti Teknologi MARA, Cawangan Pulau Pinang,Kampus  Permatang Pauh, 13500 Permatang Pauh, Pulau Pinang, Malaysia
Published: December 2022

The purpose of the research was to study the condition of prestressed monoblock concrete sleeper (PMCS) under dynamic loading experimentally and through site investigation. From this research, the value of deflection base on acceleration of concrete sleepers have been obtained. This study showed the possible correlation and relation of the PCS deflection located under a railway track. This research includes experimentation process which includes experimental investigations for dynamic loading of prestressed concrete sleepers (PCS) were examined in terms of its capability to accommodate their own design capacity and the relationships between load and displacement happened within the concrete sleeper. This study will help the railway authorities to understand and take any maintenance action to their rail infrastructure. From experimental test, the highest deflection on KTMB and EPMI rail seat section is 1.35 mm and 1.04 mm respectively. From site investigation at KM20.75, the highest deflection occured is 5.993 mm which is lower compared to the highest deflection at KM26.25 with the value of 7.06 mm.
Structural Displacement of Prestressed Concrete Sleepers Subjected to Six Coaches Commuter Load at Pinang Tunggal and Kobah
Authors:   College of Civil Engineering, Universiti Teknologi MARA Cawangan Pulau Pinang, 13500 Permatang Pauh, Penang, Malaysia, Harun Mashita , Fazlan Rozli Mohd Ikmal ,   College of Civil Engineering, Universiti Teknologi MARA Cawangan Pulau Pinang, 13500 Permatang Pauh, Penang, Malaysia, Abd Ghani Kay Dora ,   College of Civil Engineering, Universiti Teknologi MARA Cawangan Pulau Pinang, 13500 Permatang Pauh, Penang, Malaysia, Md.Amin Norliyati ,   College of Civil Engineering, Universiti Teknologi MARA, 40000 Shah Alam, Selangor, Malaysia
Published: December 2022

Nowadays, train is one of an effective transportation in Malaysia. Commuter started the operation at Central Region had extended the operation at Northern Region in 2015.Since the volume of passengers were increasing every year, it caused railway track need to be maintenance frequently due to the displacement of concrete sleeper on railway track. According KTMB representative, the displacement happened depend on the soil condition. However, this study figured out the structural displacement concrete sleeper under different of soil condition. A site investigation had been carried out along railway track from Butterworth to Alor Setar. In this study had selected Pinang Tunggal the subsoil condition silty sand in category which displacement 7.40mm and Kobah the subsoil condition under soft clay, the displacement 0.15mm accordingly. The tools that had been used in this site investigation such as vibrator machine and piezometer. The captured records transferred to software called as Dewesoft to measure the displacement of concrete sleeper. From the result had been plotted on the graph showed sandy silt had shown the highest displacement compared with the soil condition soft clay. Therefore, the roof cause of displacement of concrete sleeper at railway track may cause the water table in the subsoil. This study would assist the authority to plan the maintenance on railway track.
Pharmaceutical Compounds in Malaysian Urban Domestic Wastewater
Authors:   Department of Civil Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia, Mohd Hanafiah Zarimah , Wan Mohtar Wan Hanna Melini ,   Department of Civil Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia, Bachi’ Nur Aina ,   Department of Civil Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia, Abd Hamid Haris Hafizal ,   Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia, Abd Manan Teh Sabariah ,   Institute of Tropical Biodiversity and Sustainable Development, Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, Malaysia, Indarto Antonius ,   Department of Chemical Engineering, Institut Teknologi Bandung, Bandung, Indonesia
Published: December 2022

The emerging contaminants (ECs) is detected at trace concentration in the discharge of sewage treatment plant (STP) to the water bodies indicate incomplete removal during the treatment process. The presence of the ECs in the water has a potential impact on the ecological and human health associated with long-term ingestion of the mixture ECs compounds, and this includes the development of resistance in pathogenic bacteria, aquatic toxicity, genotoxicity, and endocrine disruption. In this study, we investigate the presence of ECs and review the occurrence of mainly of four pharmaceutical active compounds belonging to the group of non-steroidal anti-inflammatory drugs (NSAIDs) in influent and effluent of the STP. The target analytes (ibuprofen (IBU), diclofenac (DIC), ketoprofen (KET), and naproxen (NAP)) are extracted from the wastewater using the solid-phase extraction (SPE) followed by the identification and quantification using gas chromatography-mass spectrometry (GC-MS). The GC-MS detection was improved by the derivatisation technique using N-Methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) and an internal standard of Ibuprofen-D3 used as the internal standard. The targeted analytes were detected in both influent and effluent wastewater in the range 5.04±5.9 to 37.4±28.4 µg/L with removal efficiency between 11 - 86% using the current activated sludge treatment process in the STP. This concentration of compounds shows inadequate current treatment techniques to eliminate the emerging contaminants in the wastewater.