bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the University as an e-Textbook Provider of Scholarly Work
Authors: Rennie Frank , Smyth Keith , Davies Gareth , Connor Scott , Patterson Laurence
Published: August 2017

Despite the growth in the popularity of e-textbooks, there has yet to be adopted an effective model through which an academic institution can easily re-purpose the scholarly output of its staff to allow global and affordable access to students. This paper describes a research project designed to explore effective processes for the university to become a digital publisher of its own academic output. The project produced two e-textbooks, focusing on using Amazon Kindle for distribution, each book with a free companion website of open access learning resources. The use of the e-texts and the websites were then monitored for evaluation. The publication process was documented and will be made publicly available in the final report on the JISC website. In summary, the pre-publication tasks are almost identical to the production of a conventional printed book, but at publication, everything else changes. The e-textbook system minimises the problems of storage, distribution, pricing, and updating which is faced by the printed book. The companion websites provide a global space with resources complementary to the e-book, which can be updated without the requirement to amend the e-textbook. Several different categories of e-books have been identified, from short handbooks for internal course use, through open-access textbooks, to flagship commercial publications. It is recognised that these e-publications may replace or co-exist with both printed books and companion websites.
Trapped Deep Beneath the Sewage: Representation of the University in Popular Music
Authors: Gossman Peter , Illingworth Sam
Published: August 2017

This article reviews the lyrics of popular music in order to uncover how the ‘university’ is represented in this art form. The lyrics that feature university are coded into themes and these are discussed. The lyrics are initially coded to negative/positive/neutral, but group of more refined themes is also presented. The analysis reveals that whilst the university is still seen as a place of learning, the lyrics of these songs tend to present and represent the university in a negative light. The intention of this article is to promote debate into the way that the university is perceived by popular music songwriters, but also to demonstrate the importance of assessing the place of the university from outside of the (at times) myopic lens of higher educational research.
Postoperative diagnostics clinical case of the patient with kidney canсer metastasis in the thyroid gland in combination with left internal jugular vein thrombosis
Authors: Panevin Taras S. , Selivanova Liliya S. , Latkina Nonna V. , Panevin Nikolay S.
Published: August 2017

Представлено клиническое наблюдение пациентки 68 лет с жалобами на увеличение в размерах шеи, преимущественно с левой стороны, ощущение першения в горле. В ходе обследования по данным УЗИ органов шеи выявлено конгломератное образование левой доли щитовидной железы. Кроме того, в просвете в верхней трети внутренней яремной вены выявлено образование средней эхогенности. По данным последующей тонкоигольной биопсии левой доли – признаки коллоидного зоба. Пациентке проведено оперативное лечение в объеме левосторонней гемитиреоидэктомии: при ревизии левая доля значительно увеличена в размерах за счет узлового образования, доходящего до левого угла нижней челюсти, располагающегося частично загрудинно и за трахеей. По данным послеоперационного гистологического исследования выявлен метастаз светлоклеточного рака почки в левую долю щитовидной железы с признаками прорастания в окружающие сосуды и мышцы.
La construcción de las bases para la elaboración de mapas de riesgo. Una forma de intervención social desde Terapia Ocupacional
Authors: Ariño Rosana , Boffelli Mariana , Demiryi Milagros , Chiapessoni Daniela
Published: August 2017

El artículo presenta la experiencia desarrollada por estudiantes que cursaron 1º y 4º año de la Licenciatura en Terapia Ocupacional de la Universidad Nacional delLitoral (UNL), junto con agentes municipales, vecinos y organizaciones del barrio Villa Oculta de la ciudad de Santa Fe.En el marco de la Educación Experiencial, esta práctica de extensión incorporadaen el currículo posibilitó a los futuros profesionales la oportunidad de involucrarse en la resolución de problemas reales y complejos de la comunidad.El trabajo consistió en una experiencia piloto para la construcción de un mapa de riesgo, los que han funcionado como instrumentos puente entre el saber popular,la toma de decisiones y el saber académico. Experiencia posible por el interés de la Dirección de Gestión de Riesgo, vecinos, estudiantes y docentes de la UNL.
La extensión en la formación de grado del Licenciado en Turismo. El proyecto "Concientización turística ambiental en destinos costeros"
Authors: Padilla Noelia , Varisco Cristina , Benseny Graciela
Published: August 2017

Se presentan los resultados de las actividades llevadas a cabo en el proyecto de extensión “Concientización turística ambiental en destinos costeros”, de la Universidad Nacional de Mar del Plata, con el objetivo de analizar la contribuciónde la extensión a la investigación y formación de grado del Licenciado en Turismo. Se articuló con la asignatura Práctica Profesional Comunitaria, en la que los estudiantes realizaron actividades de concientización en problemáticasambientales dirigidas a diferentes actores y consensuaron acciones para mejorar la contribución del turismo al desarrollo local en Santa Clara del Mar (Argentina).Se aplicó la metodología de Investigación Acción Participativa (IAP), lo cual permitió que el accionar del grupo contribuya con la formación del Licenciadoen Turismo mediante la capacitación en temas turísticos y ambientales, en tanto que su actuación generó una mayor conciencia en los actores locales sobre el adecuado manejo de los espacios turísticos y costeros, con el consecuentefavorecimiento del desarrollo local.
Guardianes del río. Reflexiones sobre lo que hacemos y aprendemos al lado del agua
Authors: Mines Patricia , Giavedoni Ricardo
Published: August 2017

“Guardianes del río” nace como un Proyecto de Extensión de Interés Social de la Universidad Nacional del Litoral (UNL, Santa Fe, Argentina), con el objeto de integrar a los alumnos y exalumnos de la Escuela Media O. Rupp de Alto Verde en la identificación, protección y divulgación del patrimonio natural y cultural de ese barrio costero.En torno de esta propuesta se han creado, a lo largo de más de 5 años, espacios de aprendizaje para alumnos y docentes como prácticas de educación experiencial,prácticas profesionales y voluntariado, se ha motivado la investigación de espacios virtuales colaborativos y la gestión de estrategias de desarrollo sustentable conrelación al turismo y habilitado nuevos proyectos de extensión a escala mayor que fueron tema de reflexión en tesis de maestría.Desde el punto de vista del aporte al currículo universitario, experiencias como esta ofrecen escenarios para construir conocimientos distintos, para formar y sumar subjetividades, para ensayar métodos sobre el hacer, enseñar y aprender, útiles al momento de modelar de manera sustentable nuestro ambiente.
El programa Autoproducción de Alimentos. Un espacio de intersección entre extensión, investigación y docencia
Authors: Verón Jimena , Hamdan Virginia , Natinzon Paula
Published: August 2017

El presente trabajo pretende realizar una contribución teórico–metodológica a las experiencias de extensión a partir de la relación que se construye entre investigación,la docencia y la extensión en una práctica concreta: Programa Autoproducción de Alimentos de la Facultad de Ciencias Agrarias de la Universidad Nacional de Mardel Plata y del Instituto Nacional de Tecnología Agropecuaria–Balcarce.Esta actividad constituye en sí una evidencia de la parcialidad que conlleva la fragmentación entre la extensión, la docencia y la investigación. La dinámicade este tipo de acciones en y con la comunidad genera que tanto estudiantes, profesionales, docentes–investigadores y productores se asuman indistintamente en roles relevantes en cuanto a gestión, extensión, investigación y docencia, enuna forma no tradicional pero necesaria para la concreción y sustentabilidad de los proyectos consensuados, planteando interrogantes que hacen a la formaciónpraxiológica no solo de una disciplina sino de la ciencia de manera integral como proceso histórico "que está siendo".
Aprendizaje–servicio: una experiencia rural de promoción de la salud con varones adultos en Tucumán (Argentina)
Authors: Soria Analía Graciela , Guber Rosa Silvina , Tefaha Liliana Mónica , Romero Claudio
Published: August 2017

El objetivo de esta experiencia fue aumentar la demanda en salud en varones adultos. Para ello se capacitó a estudiantes de Facultad de Medicina, que realizaban su pasantía rural en Graneros, y de Bioquímica de la Universidad Nacional de Tucumán para la aplicación de un programa local de salud destinado a la promoción, detección de factores de riesgo y enfermedades prevalentes en varones adultos. Participaron 66 estudiantes de Medicina y 23 de Bioquímica.Las estrategias más usadas fueron: difusión radial, carteles en lugares de mayor concurrencia, visita domiciliaria con invitación a participar. Los estudiantes evaluaron la actividad como una experiencia positiva. El 70 % de ellos tuvo muy buen desempeño. De los 678 varones invitados, el 40 % concurrió para la atención y se lo incluyó en un programa de seguimiento en centro de Atención Primaria de la Salud. El trabajo de modo sistemático desde el grado favorece en los estudiantes el desarrollo de habilidades y modifica su percepción de las necesidades reales de salud en poblaciones deprimidas.
Enseñanza, investigación y extensión: tres prácticas articuladas en la cátedra de Didáctica General de la Universidad Nacional del Litoral
Authors: Baraldi Victoria
Published: August 2017

En el presente artículo se expresan los modos en que al interior de una cátedra se vinculan y retroalimentan la práctica de extensión con las prácticas de enseñanzay de investigación. En primer lugar, se presentan las dos principales coordenadas desde donde se escribe el texto: La Universidad Nacional del Litoral y el campo de la didáctica.Allí se mencionan rasgos identitarios de la creación de esta institución que tienen vigencia en la actualidad y algunas de las particularidades de la didáctica.En segundo lugar, se describen tres situaciones concretas en las que en la cátedra de Didáctica General se conjugaron las tres funciones sustantivas de la universidad,focalizando en los modos en que una de ellas influyó particularmente sobre las otras.Finalmente, se enuncian los principales principios de la cátedra mencionada.
Saberes e práticas da docência em hospital: vivências do pedagogo em formação através da extensão universitária
Authors: Sousa Rabelo Francy
Published: August 2017

Este texto investigou a relação dos saberes e práticas da docência na formação inicial vivenciada no projeto de extensão “Estudar, uma ação Saudável”. O referido projeto se desenvolve no Hospital Universitário da Universidade Federal do Maranhão com atividades educativas para crianças hospitalizadas. Utiliza na pesquisa, o método de estudo de caso e a entrevista semiestruturada comoinstrumento de coleta de dados e teve como público alvo, as alunas do curso de Pedagogia da Universidade Federal de Maranhão, participantes do projeto.A pesquisa mostrou que a extensão universitária favorece a formação inicial, novos espaços de atuação já previsto nas Diretrizes Curriculares Nacionais para o Curso de Pedagogia, evidenciou que os saberes docentes foram reelaborados e construídos pelas alunas/professoras de acordo com suas experiências de ensino e a relação com o espaço hospitalar para o benefício das crianças hospitalizadas.
Proyectos de extensión como promotores de un aprendizaje significativo para alumnos de Ciencias Veterinarias en la Universidad Nacional de Rosario
Authors: Biolatto Renato , Vallone Raúl , Vallone Carla , Bassi Andrés
Published: August 2017

Conocemos a necesidad de articular la universidad con la sociedad y sabemos del valor que las prácticas educativas solidarias, como voluntariado, práctica preprofesional o aprendizaje servicio tienen sobre la formación de futurosprofesionales. Si bien en la Universidad Nacional de Rosario (UNR), la extensión ha cobrando vigencia en cantidad y calidad de proyectos, los mismos, comparados con los de investigación, son escasos y con poca participación estudiantil. En la convocatoria 2015 de la Secretaría de Extensión UNR, en Ciencias Veterinarias no se alcanzó siquiera a cubrir el cupo asignado de proyectos a subsidiar.El diseño curricular no prevé la incorporación de experiencias de extensión en articulación con las asignaturas de cursado regular. No obstante, experienciascomo la que se ha de relatar dan cuenta del valor de la formación social y de la necesidad de colocar a los alumnos en situaciones reales, distintas de las abordadas en el aula.
La Universidad escucha a las escuelas: balance de una acción sinérgica
Authors: Rotondi Gabriela
Published: August 2017

El presente trabajo se plantea el desafío de trasmitir una experiencia que se define desde sus fundamentos como sinérgica. Se trata de las apuestas extensionistas de la cátedra Teoría, Espacios y Estrategias de intervenciónIV – institucional, correspondiente a la Licenciatura en Trabajo Social, de la Facultad de Ciencias Sociales de la Universidad Nacional de Córdoba.Intentaremos dar cuenta de algunos de los vínculos planteados entre las tres funciones universitarias (docencia, investigación y extensión) y su presencia en la instancia de cátedra, como núcleo básico de la acción entre docentes yestudiantes. Tomaremos el período desarrollado desde 2001–2016, período en el cual el trabajo extensionista se institucionaliza a partir de una propuesta, el Programa “La Universidad escucha las escuelas”, que toma cuerpo a partir de la hiperinflación de 2001, momento en que la cátedra lo fundamenta y diseña en el marco de un contexto que instala un fuerte cambio en las escuelas públicas, respecto de sus servicios sociales a la comunidad.
La Facultad de Humanidades en la cárcel: formación docente, investigación y extensión
Authors: Hidalgo Brenda , Alanís Mario Arnoldo
Published: August 2017

Las prácticas de extensión universitaria han permitido la construcción de vínculos entre actividades académicas y la comunidad local y se han establecido líneas de acción que apuestan al fortalecimiento de políticas de inclusión mediante la creación de programas, los cuales promueven el desarrollo de proyectos de investigación y la realización de propuestas interdisciplinarias con criterios de participación y responsabilidad entre las partes componentes. En el presente trabajo se propone dar a conocer algunos de los desempeños en el marco del programa “La Facultad de Humanidades en la cárcel”, perteneciente a la Universidad Nacional de Catamarca. Consideramos que tales actividades han permitido, tanto en la formación como en la investigación, generar procesos que nos sitúan frente a una función social y política de fortalecer espacios que garanticen la educación como un derecho social, trascendiendo contextos.
Konseptualisasi dan Internalisasi Nilai Profetik: Upaya Membangun Demokrasi Inklusif bagi Kaum Difabel di Indonesia
Authors: Fikri Abdullah
Published: August 2017

This paper focuses on the disability in the context of inclusive democracy that is based on the prophetic values. There are two terms used in this paper. First, inclusive democracy; this term asserts that the people with disability are not the object in a social and political system, conversely, the people with disability are positioned as the subject in citizenship. The people with disability are part of the political system and society and they have the rights to engage and compete in the political practices. Second, “prophetic values” that refers to the elaboration of disability studies and Islamic studies, where the later is related to the earlier. Disability studies with the prophetic social science are prominent as a social transformation in order to get a better humanist and transcendence understanding of disability in the local context of Indonesia. The result of this study shows that the inclusive democracy, in terms of Indonesian local context, is constructed by four prophetic values: humanism, liberation, transcendence and inclusive society.[Tulisan ini akan membahas difabilitas dalam konteks demokrasi inklusif berbasis nilai-nilai profetik. Ada dua term yang digunakan dalam tulisan ini. Pertama, “demokrasi inklusif”; term ini ingin menegaskan bahwa difabel bukan lagi sebagai orang yang hanya dijadikan objek saja, akan tetapi kaum difabel diposisikan sebagai subjek warganegara. Dengan kata lain, kaum difabel merupakan bagian dari entitas sistem politik dan sistem masyarakat, yang memiliki hak untuk ikut serta dalam kompetisi politik praktis. Kedua, “nilai-nilai profetik”; sebagai elaborasi kajian difabilitas dan studi Islam, maka penting melakukan interelasi antara difabilitas dengan nilai-nilai profetik. Kajian disabilitas dengan Ilmu Sosial Profetik (ISP), sebagai upaya melakukan transformasi sosial, agar  didapatkan sebuah pemahaman yang lebih humanis-transenden terhadap kaum difabel dalam konteks ke-Indonesiaan. Adapun hasil dari kajian ini adalah bahwa demokrasi inklusif berbasis paradigma profetik dalam konteks ke-Indonesiaan, dikonstruksi atas empat pilar, yaitu nilai humanisasi, liberasi, transendensi, dan masyarakat inklusif.]
Layered Learning, Eustress, and Support: Impact of a Pre-Service-Learning Training on Students’ Self-Efficacy in Teaching in the Community
Authors: Cooke Natalie K. , Pursifull Anne K. , Jones Kerry M. , Goodell L. Suzanne
Published: August 2017

Service-learning programs provide students with opportunities to gain discipline-specific skills, while providing community organizations with a steady pool of volunteers. However, because students may lack the skills needed to effectively serve the community, skills-based training may need to be incorporated into service-learning courses. Students in a community nutrition service-learning course engaged in 7 weeks of training before teaching a 6-week-long nutrition education course to community members. The training included three layers of activities: (1) basic activities, which introduced the students to material necessary to build skills for their service-learning experience; (2) directed activities, which allowed them to refine a targeted skillset; (3) and collective activities, which allowed for the application of multiple skills. Through qualitative interviews with 12 of the 19 students who had been enrolled in the course, we determined the impact of a pre-service-learning training program on the development of the skills necessary to successfully teach a nutrition education course. Thematic analysis of the data revealed two major themes: (1) “layered learning” activities facilitate skill building and (2) a stressful, yet supportive, environment facilitates growth. Together, these aspects of course design allow students to develop skills and their self-efficacy in those skills. Therefore, instructors who plan to incorporate service-learning into their nutrition courses may benefit from designing a pre-service-learning training to improve student learning outcomes.
Does Team Formation Impact Student Performance, Effort and Attitudes in a College Course Employing Collaborative Learning?
Authors: Pociask Sarah E. , Gross David , Shih Mei-Yau
Published: August 2017

The literature on team-based learning emphasizes the importance of team composition and team design, and it is recommended that instructors organize teams to ensure diversity of team members and optimal team performance. But does the method of team formation actually impact student performance? The goal of the present study was to examine whether different team formation methods would affect individual and team performance outcomes and student attitudes in an undergraduate general education course. Across three different sections of the same course, teams were either designed by the instructor, by the students, or randomly by a computer program. We found that teams designed by the course instructor were more diverse, but that students in these teams performed no better than their peers in self-selected or randomly assigned teams. Because student performance was similar regardless of team formation method, these findings suggest that student formed teams can be a reasonable option for instructors to consider when planning a team-based course.
Learning to Learn: Lessons from a Collaboration
Authors: Chadha Anita
Published: August 2017

E-learning has become one of the primary ways to deliver education around the globe. Research is keeping pace with the use of various techno-aids as educators evaluate how to effectively use these aids in an ever-changing e-classroom. Adding to this body of work, and in assessing the effectiveness of techno-tools, this study evaluates meaningful and deliberative exchanges of online discussions towards building an inclusive online classroom. Unknown to each participant were the gender, race, ethnicity, religious beliefs, course level, and mode of instruction of the other students in the study. These unknowns are important in determining how civically engaged participants are in their discussions with each other. Are they creating dialogue and being reflective irrespective of differing instruction types or levels? A secondary focus of this study, is to provide suggestions in constructing purposefully created online e-learning communities. This project’s outcomes have important implications in the ever-demanding need to design effective online communities.
EFL ORAL SKILLS BEHAVIOR WHEN IMPLEMENTING BLENDED LEARNING IN A CONTENT-SUBJECT TEACHERS’1 PROFESSIONAL DEVELOPMENT COURSE
Authors: Sanchez Narvaez Natalia , Chavarro Vargas Sergio Alberto
Published: August 2017

AbstractToday’s world demands the use of the English language in different areas of knowledge. Besides, the increasing use of technology in educational settings (Zandi et al, 2014; Murray, 2014) encourages teachers to restate their professional development by focusing their efforts on becoming proficient in the use of Information and Communication Technologies (ICTs) in language lessons (Chen et al, 2009). Following the previous ideas, this qualitative action research project intended to describe Content-subject teachers’ EFL oral behavior when blended learning was implemented in a professional development course; and to determine the influence of Blended learning in EFL oral skills behavior. The participants were seven content- subject teachers from a private school in Huila, Colombia. Data were gathered via in-depth interviews, class observations, video recording analysis, teacher’s reflection, students’ artifacts and a survey. The data were collected during the implementation of an English blended course, in which twelve lessons were divided into six face-to-face sessions and six online meetings. The findings suggest that EFL oral skills behavior is connected with use of vocabulary, use of body language, pronunciation and intonation patterns, production of chunks of language, monitoring oral production and, motivation and engagement. Besides this, Blended learning influenced participants’ oral production too.Keywords: blended learning, content-subject teachers, EFL2 oral skills, professional development.1. Educators who teach content subjects in Spanish2. English as a Foreign Language
ELT teachers working in underprivileged districts of Turkey and their perspective of continuous professional development opportunities
Authors: Tunaz Mehmet , Önem Engin Evrim
Published: August 2017

The purpose of this research is to enquire the ELT teachers’ perspective of continuous professional development under restricted conditions they are obliged to teach English. Therefore, 20 EFL teachers who have been working at different state schools in the remote villages of southeast region of Turkey were selected as the participants of the inquiry. The data were collected in two different processes. First, all the teachers in the study were interviewed to answer the questions in the first part of the survey individually. Then, randomly selected 12 teachers were separated into two groups for online focus-group discussions, which were held in a semi-structured context by leading questions adapted from Brown (2013). Data collection processes were audio-recorded, and the qualitative data obtained from interviews and focus group discussions were coded and clustered to form specific themes. The results of the research revealed that teachers working in underprivileged districts of Turkey: (a) believe the crucial contribution of professional development activities for teacher quality and/or student achievement (b) have very limited opportunities and options for sustained professional development, and (c) think that the times allocated for professional development activities should be increased. Moreover, teachers these teachers (d) hope to take place in the planning phase of professional development activities, and (e) are dissatisfied with unfair financial situation. Upon the analysis of these items stated in the results, male teachers were found to focus on more general ideas compared to female teachers (item a and item b). On the other hand, the results indicated that female teachers focused on specific ideas statistically more often compared to male teachers (item c and item d). The teachers did not show statistical gender difference in terms of financial limitations (item e). The results of the research might be generalized to the similar contexts in other underprivileged districts, and similar researches might be conducted with teachers of other fields in order to reach results that are more generalizable.
Smoking Related Systemic and Oral Diseases
Authors: Vellappally Sajith , Fiala Zdeněk , Šmejkalová Jindra , Jacob Vimal , Somanathan Rakesh
Published: August 2017

This article reviewed smoking related systemic diseases and oral diseases. Smoking is related to lung cancer, cardiovascular diseases and many other systemic diseases. Cigarette smoke affects the oral cavity first, so it is evident that smoking has many negative influences on oral cavity, for example, staining of teeth and dental restorations, wound healing, reduction of the ability to smell and taste, and development of oral diseases such as oral cancer, periodontitis, smoker’s palate, smoker’s melanosis, hairy tongue, leukoplakia, oral candidiasis and implant survival rate. The article also discusses the relationship between smoking and dental caries in detail.
Soft Tissue Esthetics in Implant Dentistry
Authors: Somanathan Rakesh V. , Šimůnek Antonín , Bukač Josef , Brázda Tomáš , Kopecká Dana
Published: August 2017

Dental implants have been considered to be a successful treatment modality. Recently, achieving a good osseointegration is not the ultimate goal for the restorative dentist. Successful implant treatment demands the best gingival esthetic success along with stability and function of the implant. This study was performed to obtain answers to some controversial points pertaining to esthetics and function of implants in maxilla. Immediate flapless implantation into the extraction sockets in maxillary anterior zone is an emerging treatment option in dentistry- the esthetic success of which was in debate for long. The proposed study compared the esthetic success of immediate flapless implants (ILA), to immediate implants with the need for flap (ILB) and, delayed implants (DSL) in single tooth restorations, in the anterior region of the maxilla. The other aim of the study was to find out if any relation exists between the interproximal crestal bone height and papilla height. Analysis was done irrespective of treatment procedure in the same study group using periodontal sounding and radiographs to find out the relation. From the study involving 106 participants, including 21 ILA, 22 ILB and 63 DSL cases, we received highest papillary index score of 2.6 average from group ILA, followed by ILB and DSL, after 3 months of prosthetic loading. From the periodontal sounding and radiographic study it was evident that, when the distance between the base of the contact point of crowns and height of interproximal bone was less than 5, the papilla was present 100 % of the time, but when the distance increased to 6 and more than 7 mm, the papilla was present only 46.5 and 24 percentage of the time respectively.
Human Dental Pulp Stem Cells – Isolation and Long Term Cultivation
Authors: Suchánek Jakub , Soukup Tomáš , Ivančaková Romana , Karbanová Jana , Hubková Věra , Pytlík Robert , Kučerová Lenka
Published: August 2017

Human adult mesenchymal stem cells (MSCs) are rare elements living in various organs (e.g. bone marrow, skeletal muscle), with capability to differentiate in various cell types (e.g. chondrocytes, adipocytes and osteoblasts). In the year 2000, Gronthos and co-workers isolated stem cells from the human dental pulp (DPSCs). Later on, stem cells from exfoliated tooth were also obtained. The aims of our study were to establish protocol of DPSCs isolation and to cultivate DPSCs either from adult or exfoliated tooth, and to compare these cells with mesenchymal progenitor cell (MPCs) cultures. MPCs were isolated from the human bone marrow of proximal femur. DPSCs were isolated from deciduous and permanent teeth. Both cell types were cultivated under the same conditions in the media with 2 % of FCS supplemented with PDGF and EGF growth factors. We have cultivated undifferentiated DPSCs for long time, over 60 population doublings in cultivation media designed for bone marrow MPCs. After reaching Hayflick’s limit, they still have normal karyotype. Initial doubling time of our cultures was from 12 to 50 hours for first 40 population doublings, after reaching 50 population doublings, doubling time had increased to 60–90 hours. Regression analysis of uncumulated population doublings proved tight dependence of population doublings on passage number and slow decrease of proliferation potential. In comparison with bone marrow MPCs, DPSCs share similar biological characteristics and stem cell properties. The results of our experiments proved that the DPSCs and MPCs are highly proliferative, clonogenic cells that can be expanded beyond Hayflick’s limit and remain cytogenetically stable. Moreover we have probably isolated two different populations of DPSCs. These DPSCs lines differed one from another in morphology. Because of their high proliferative and differentiation potential, DPSCs can become more attractive, easily accessible source of adult stem cells for therapeutic purposes.
Evaluation of Potency of Known Oximes (Pralidoxime, Trimedoxime, HI-6, Methoxime, Obidoxime) to in vitro Reactivate Acetylcholinesterase Inhibited by Pesticides (Chlorpyrifos and Methylchlorpyrifos and Nerve Agent (Russian VX)
Authors: Musílek Kamil , Kuča Kamil , Jun Daniel
Published: August 2017

Nerve agents and pesticides belong to the group of organophosphates. They are able to inhibit irreversibly the enzyme acetylcholinesterase (AChE). Acetylcholinesterase reactivators were designed for the treatment of nerve agent intoxications. Their potency to reactivate pesticide-inhibited AChE was many times evaluated. In this study, five commonly used AChE reactivators (pralidoxime, methoxime, HI-6, obidoxime, trimedoxime) for the reactivation of AChE inhibited by two pesticides (chlorpyrifos and methylchlorpyrifos) were used. Russian VX (nerve agent) as a member of nerve agents’ family was taken for comparison. Obtained results show that oximes developed against nerve agent intoxication are less effective for intoxication with organophosphorus pesticides. Especially, methylchlorpyrifos-inhibited AChE was found to be poorly reactivated by the compounds used.
Phenotype Analysis of Tumour-infiltrating Lymphocytes and Lymphocytes in Peripheral Blood in Patients with Renal Carcinoma
Authors: Kopecký Otakar , Lukešová Šárka , Vroblová Vladimíra , Vokurková Doris , Morávek Petr , Šafránek Hynek , Hlávková Dagmar , Souček Petr
Published: August 2017

Introduction: When checking tumour growth, a number of observations indicate that the immune system plays a significant role in patients with renal cell carcinoma (RCC). Infiltration by lymphocytes (tumour infiltrating lymphocytes, TILs) is more prevalent in RCC than any other tumours. T lymphocytes are the dominant population of TIL cells. Views concerning the role of T lymphocytic subpopulations, B lymphocytes and NK cells in an anti-tumour response are not established. Aim: The aim is to determine the phenotype and activation of T and B lymphocytic subpopulations and NK cells and to compare their representation in tumour stroma and peripheral blood lymphocytes (PBL) in patients with RCC. Material and methods: Samples of peripheral blood taken from the cubital and renal veins and tumour stroma cells were obtained from 44 patients in the course of their surgeries carried out due to primary RCC. TILs were isolated from mechanically disintegrated tumour tissue. Immunophenotype multiparametric analysis of PBL and TILs was carried out. Their surface and activation characteristics were determined by means of flow cytometer. Results: CD3+T lymphocytes (69.7 %) were the main population of TILs. The number of CD3+/CD8+T lymphocytes was significantly higher in TILs, 42.6 % (p< 0.01), while CD4+T lymphocytes were the majority population in peripheral blood, 41.35 % (p < 0.001). The representation of CD3+/69+T lymphocytes was significantly higher in TILs, 32.9 %, compared to PBL (p<0.001). On the contrary, the numbers of CD3+/CD25+, CD8+/57+and CD4+/RA+(naive CD4+T lymphocytes) were higher in PBL (p<0.001). The differences in representation of (CD3-/16+56+) NK cells and CD3+/DR+T cells in TILs and PBL were not significant. Conclusion: The above-mentioned results prove that the characteristics and intensity of anti-tumour responses are different in compared compartments (tumour/PBL). CD3+/CD8+T lymphocytes are the dominant lymphocytic population of TILs. The knowledge of the phenotype and functions of effector cells, which are responsible for anti-tumour response, are the basic precondition for understanding the anti-tumour immune response and the cause of its failure.
Variant Abductor Pollicis Longus Muscle: a Case Report
Authors: Shipra Paul , Srijit Das
Published: August 2017

Abductor pollicis longus (APL) muscle is known to exhibit different variations with respect to its attachments. Various studies have reported the splitting of the APL muscle. Comparative anatomical findings of split insertion of APL is commonly found in chimpanzees, gorillas and gibbons. In the present study, we describe an anomalous APL muscle, which originated from the posterior surface of the shaft of the radius and ulna and traversed a course deep to the extensor retinaculum. Interestingly, immediately after emerging form the deeper aspect of extensor retinaculum, the thin tendon of the APL muscle continued again as a muscular belly in relation to the dorsolateral part of the 1st metacarpal bone, to end as a tendon with its attachment to the base of the proximal phalanx. Such an unusual variation of APL with its attachment into proximal phalanx is a rare finding and may be of importance in altering the mechanics of the thumb during abduction. The clinical significance of such an anatomical variation of APL may be important during reconstructive surgeries involving thumb and also of academic interest.
Forefoot Complaints – the Morton’s Metatarsalgia. The Role of MR Imaging
Authors: Birbilis Theodossios , Theodoropoulou Efthymia , Koulalis Dimitrios
Published: August 2017

An illustrated case with Morton’s metatarsalgia is presented. MR imaging was helpful for determining the presence, location and magnitude of intermetatarsal neuroma. Moreover, it had a large influence on the differential diagnostic thinking because many disorders may produce forefoot complaints mimicking Morton’s metatarsalgia.
Confucianism as an “Organized Religion”
Authors: Chen Na , Fan Lizhu
Published: August 2017

This is an ethnographic study of the Confucian Congregation—an emerging religious group in Fujian Province, southeast China—with an account of the Congregation’s origin, belief and rituals, organization, and development strategy. The Congregation started with one person providing supernatural healings, and it developed into an “organized religion” with hundreds of members in seven franchised branches. Furthermore, by taking advantage of the contemporary trend of the revival of Confucianism in China, Congregation leaders were even able to achieve a seemingly impossible feat—a legitimate status for their “superstitious” group.
Rejecting Women’s Ordination
Authors: Vance Laura
Published: August 2017

The July 2015 meeting of the Adventist General Conference was dominated by an often contentious debate about women’s ordination. Though founded by a female charismatic leader, Adventists were contesting women’s ordination by at least 1881, and the contemporary denomination has studied the question for more than four decades. Tension has burgeoned in recent years as some regional Seventh-day Adventist unions have ordained women despite the lack of movement-wide policy change. In July 2015, as delegates deliberated on a motion to allow each division of the world church to decide the question of women’s ordination for itself, the gathering saw an unusual degree of discord, and this disagreement about gender and women’s roles spilled over from the ordination debate into discussions of other agenda items. Despite a “No” vote on the motion, the controversy surrounding women’s ordination persists in Adventism.
Review of toxicity studies of carbon nanotubes
Authors: Kobayashi Norihiro , Izumi Hiroto , Morimoto Yasuo
Published: August 2017

Objective

We reviewed studies on pulmonary, reproductive, and developmental toxicity caused by carbon nanotubes (CNTs). In paricular, we analyzed how CNT exposure affects the several processes of pulmonary toxicity, including inflammation, injury, fibrosis, and pulmonary tumors.

Methods

In pulmonary toxicity, there are various processes, including inflammation, injury, fibrosis, respiratory tumor in the lungs, and biopersistence of CNTs and genotoxicity as tumor-related factors, to develop the respiratory tumor. We evaluated the evidence for the carcinogenicity of CNTs in each process. In the fields of reproductive and developmental toxicity, studies of CNTs have been conducted mainly with mice. We summarized the findings of reproductive and developmental toxicity studies of CNTs.

Results

In animal studies, exposure to CNTs induced sustained inflammation, fibrosis, lung cancer following long-term inhalation, and gene damage in the lung. CNTs also showed high biopersistence in animal studies. Fetal malformations after intravenous and intraperitoneal injections and intratracheal instillation, fetal loss after intravenous injection, behavioral changes in offsprings after intraperitoneal injection, and a delay in the delivery of the first litter after intratracheal instillation were reported in miceadministered multi-walled carbon nanotubes (MWCNTs). Single-walled carbon nanotubes (SWCNTs) appeared to be embryolethal and teratogenic in mice when given by intravenous injection; moreover, the tubes induced death and growth retardation in chicken embryos.

Conclusion

CNTs are considered to have carcinogenicity and can cause lung tumors. However, the carcinogenicity of CNTs may attenuate if the fiber length is shorter. The available data provide initial information on the potential reproductive and developmental toxicity of CNTs.
Fitoösztrogének a menopauza terápiájában
Authors: Remport Júlia , Blázovics Anna
Published: August 2017

Abstract:

In previous centuries many women did not even live until their menopause years due to poor economic conditions, deficiencies of medicine, epidemics and wars. Nowadays in the developed countries, people live until they are 75–80 years old, and with the expansion of average age, the number of people affected by menopause and the years spent in that state increase. Nowadays women spend one third of their lives in the menopausal stage. The only effective way to treat unpleasant symptoms for centuries was with the use of herbs, and the knowledge about them spread through oral tradition. In the 20th century, this therapeutic form was pushed into the background by the development of synthetic drug production and the introduction of hormone replacement therapy. Thanks to the influence of media in the 20th century, women began to have the social need for preserving their beauty and youth for as long as they could. Hormone replacement therapy enjoyed great popularity because women were temporarily relieved of their life quality-impairing menopausal symptoms, but years later it turned out that hormone replacement therapy could pose serious risks. A distinct advantage of herbal therapy is the more advantageous side-effect-profile opposite the used synthetics in hormone replacement therapy. Women are therefore happy to turn to valuable and well-tried natural therapies, which have been used for thousands of years. There is growing interest in herbal remedies. Studying the effects of phytoestrogens has now become an active area for research. However, the results of studies in animals and humans are controversial, some sources suggest that phytoestrogens are effective and safe, other authors claim that they are ineffective in menopause or they have particularly dangerous properties, and cannot be recommended to everyone. It is important to address this issue for the sake of health, mental health and safety of women, and so it is necessary to assess the benefits and the risks before applying them. Orv Hetil. 2017; 158(32): 1243–1251.
D-vitamin-anyagcsere és osteoporosis szisztémás sclerosisban
Authors: Szamosi Szilvia , Horváth Ágnes , Szekanecz Zoltán , Szűcs Gabriella
Published: August 2017

Abstract:

In the past few years more and more data have become available on the important role of vitamin D in immunological processes and inflammation. The role of vitamin D deficiency in the pathogenesis as well as in disease progression of different autoimmune and inflammatory conditions is suspected. Vitamin D deficiency is prevalent in several autoimmune diseases, including systemic sclerosis. Hypovitaminosis has been found to be associated with low bone mineral density and higher prevalence of osteoporosis in this group of patients. Determinants of low bone density in SSc are poorly understood. Studies have shown the importance of both traditional osteoporotic as well as disease-specific factors (extent of skin involvement, presence of internal organ manifestation, malabsorption, systemic sclerosis subtype, serological profile, medication) in the development of low bone mineral density. The relationship between low bone density in systemic sclerosis patients and the above mentioned risk factors may be more complex and the real role of each factor is unclear. Yet very few studies reported clinically relevant low bone mass outcomes such as fracture risk assessment and fracture associated mortality in scleroderma. This review aims to synthesize data about the essential role of vitamin D in immune homeostasis as well as the prevalence of hypovitaminosis, low bone density, changes in bone turnover markers and presence of osteoporosis in scleroderma patients. Orv Hetil. 2017; 158(32): 1252–1258.
Resp 1630097/RJ (Informativo 603 STJ – Publicado em 7 de junho de 2017) – Prova ilícita e autoincriminação
Authors: Varalli Janaina T. Daniel
Published: August 2017

O réu foi condenado, em 01º grau de jurisdição a 07 anos de reclusão, em regime fechado e multa de 700 dias-multa por tráfico ilícito de entorpecentes (art. 33 da Lei 11.343/2006). A prova que baseou a condenação foi uma ligação feita pela mãe do réu durante uma abordagem policial.
Ensino Público e acesso ao Ensino Superior: a questão das cotas
Authors: Maia Danielle Costa , Vieira Dos Santos Débora , Marques Gustavo Henrique Cavalcante , Brasil Iliane Rodrigues Rego , Macedo Lucas Carvalho , Araújo Stéphanye Lima , Vilmar da Silva José
Published: August 2017

O presente artigo tem por objetivo tratar sobre o ensino público, bem como o acesso ao ensino superior, além de uma abordagem sobre a questão da adoção de medidas de cotas raciais e para pessoas de baixa renda. Para tanto, será exposto uma análise sobre a condição em que o ensino público se encontra, bem como as consequências dos quais a adoção de contas geram.
Analytical model for non-uniform corrosion-induced concrete cracking
Authors: Yang Shangtong , Li Kefei , Li Chun-Qing
Published: August 2017

Corrosion-induced concrete cracking is one of the major deterioration mechanisms for reinforced concrete structures, and the corrosion process is not uniform along the circumference of the reinforcement. To model the stress distribution in concrete and determine the initiation of concrete cracking, a realistic non-uniform corrosion model needs to be developed. In this paper, a time-dependent corrosion model, producing non-uniform expansion to concrete, is first established. The stresses in concrete are then formulated through the employment of complex functions. The time to initiation of concrete cracking is determined and related to a number of material, geometric and corrosion parameters. The derived analytical model is verified by comparing the results with those from experimental tests reported in the literature. It is concluded that this model is one of very few analytical models that can determine the stresses in concrete caused by non-uniform corrosion of the reinforcement.
High quality DNA from Fusarium oxysporum conidia suitable for library preparation and long read sequencing with PacBio v4
Authors: Kaur Sukhwinder , Quyen Anh Pham not provided , and Lynn Epstein not provided
Published: August 2017

This protocol is for isolation of high quality, high molecular weight DNA (20 kb and larger) that is suitable for PacBio library preparation. This protocol has been tested on lyophilized conidia from multiple isolates of Fusarium oxysporum, including f. sp. apii, f. sp. ciceris, and f. sp. lycopersici.
Corrosion Inhibition of Mild Steel in 0.5N H2SO4 Solution by Tribulus terrestris (fruit) Extract
Authors: Chaudhary Suchitra , Tak Rakesh K. , Duchaniya Rajendra Kumar
Published: August 2017

The corrosion inhibition efficiency of alcoholic extract of fruits of plant Tribulus terrestris for mild steel in 0.5N H2SO4 solution has been studied in relation to concentration of inhibitor by Mass Loss, Potentiodynamic Polarisation and Electrochemical Impedance Spectroscopy methods. The results indicate that Tribulus terrestris fruit extract used in liquid H2SO4 effectively reduces the corrosion rate of mild steel and act as a good corrosion inhibitor. It is also observed that inhibition efficiency increases with inhibitor concentration but it decreases with increase in temperature. The thermodynamic parameters reveal that the inhibition of corrosion is due to adsorption of the inhibitor on the metal surface. The negative free energy values show spontaneity of the adsorption process in accordance with Langmuir adsorption isotherm.