bluuebunny/crossref_metadata_2025 huggingface dataset:
BRONCHOSCOPY IN SPACE: OVERCOMING MEDICAL AND ENGINEERING CHALLENGES IN A ZERO-GRAVITY ENVIRONMENT
Authors: Tom Joseph Chrison , S. Appanavar Vinaykumar
Published: February 2025

Performing medical procedures in space introduces unique challenges due to the absence of gravity and limited access to Earth-based medical resources. Bronchoscopy, an essential procedure for diagnosing and treating respiratory tract issues, becomes more complicated in a microgravity environment. This paper discusses the key medical and engineering challenges involved in performing bronchoscopy aboard spacecraft, focusing on fiberoptic engineering and the adaptations required for successful interventions. Solutions for managing secretion clearance, instrument stabilization, and patient positioning in zero gravity are explored, with an emphasis on case studies, hypothetical scenarios, and future advancements in.
Intra and interspecific competition in spatial arrangements of cassava and peanut intercropping
Authors: Soares Maria Beatriz Bernardes , Finoto Everton Luis , Albuquerque José de Anchieta Alves de , Barreto Glauber Ferreira , Neto João Luiz Lopes Monteiro , Alves José Maria Arcanjo , Alvarez Richard Alcides Molina , Braz Laura Soliane Cruz , Gonçalves Anderson Carlos de Melo , da Silva Edgley Soares
Published: February 2025

Intercropping cassava with peanuts in different plant arrangements can increase cassava crop yield. Nonetheless, no experimental evidence has been established on the ubiquitous forces of intra and interspecific competitions affecting cassava development, crop yield, and land use efficiency (LUE) in intercropping. Therefore, this study aimed to evaluate the intra- and interspecific competition impacts on cassava culture, crop productivity, and LUE under different spatial arrangements in the cassava-peanut consortium. The experiment was arranged in randomized blocks with 5 treatments and 5 replications. The treatments were: cassava in monoculture (T1); cassava + peanuts between the cassava rows (T2); cassava + peanuts in a double row between the cassava rows (T3); cassava planted in a double row + peanuts between double rows of cassava (T4); peanuts in monoculture (T5). The results reveal that intercropping affects the vegetative growth rate of cassava and that denser spatial arrangements promote greater inter- or intraspecific competition between cassava and peanut plants, affecting the height, branching, root length, diameter, and commercial yield of cassava roots. However, less dense arrangements provide more advantageous conditions for cassava root growth, resulting in less root loss. The productivity of cassava and peanut roots and grains was higher in single cultivation. The intercrop of cassava in a single row with peanuts in the alley and the intercrop of cassava in a double row with peanuts presented satisfactory ELU, with an average of 1.30.
Plant growth and micronutrient contents of yellow passion fruit subjected to organic fertilization
Authors: Viégas Ismael de Jesus Matos , da Silva Sávia Poliana , Alves José Darlon Nascimento , Franco Tayssa Menezes , Okumura Ricardo Shigueru , Silva Diocléa Almeida Seabra , Araújo Carlos Valmison da Silva , Filho Michel Sauma , Conceição Heráclito Eugênio Oliveira da
Published: February 2025

The utilization of organic fertilizers to enhance plant growth has witnessed a surge in recent years. This is attributed to the beneficial effects of organic matter on intensely cultivated soils, coupled with the high costs of mineral fertilizers for farmers. Here, we conducted an experiment to assess the impact of organic compound doses on the growth and nutritional status of passion fruit. The experiment was conducted in a greenhouse at the Universidade Federal Rural da Amazônia, in Belém, Pará State, Brazil. The experimental design was completely randomized with five treatments and four replications. Each experimental plot comprised a vase with a volume of 3.6 dm3 of soil and a yellow passion fruit seedling (Passiflora edulis f. flavicarpa Deg.). Five rates of organic fertilizer (0%, 15%, 30%, 45%, and 60%) were tested out of the total volume of the substrate. The organic fertilizer (pH = 6.9, N = 15.2 g kg-1, and C = 109.7 g kg-1) was prepared by mixing 10% chicken manure, 20% duck manure, 15% cassava bark, 15% cassava leaf, 15% bean straw, 15% rice husk, and 10% corn cob. The optimal results of stem diameter, number of leaves, and total dry mass were achieved with a dose of 60% of the organic fertilizer at 97 days. The content and accumulation of micronutrients in the foliar tissue of yellow passion fruit plants followed the descending order: Fe˃B˃Mn˃Zn˃Cu. It is recommended a dose of 60% of organic fertilizer to be used for the production of yellow passion fruit seedlings in the edaphoclimatic conditions of the Brazilian eastern Amazon.
ÓTICA DOCENTE SOBRE DEFICIÊNCIA VISUAL
Authors: Oliveira Flávia Freire de , Medeiros Paulo Ivo Silva de
Published: February 2025

É instituído por lei o direito da inclusão de alunos com necessidades educacionais específicas como a deficiência visual na sala regular de ensino. Logo, é importante que haja formação inicial e continuada de docentes da educação básica para o trabalho pedagógico para com esse público, visando uma melhor relação e efetividade da qualidade do ensino-aprendizagem. Assim, este trabalho objetivou apresentar estratégias pedagógicas utilizadas por docentes da rede básica de ensino para trabalhar com estudantes com deficiência visual, bem como em discutir a importância da formação inicial e continuada nessa perspectiva. Foi realizada uma pesquisa através de formulário eletrônico com 26 professores de diversas áreas do conhecimento. Os dados foram analisados através de Análise de Conteúdo. Nossa análise indica que, apesar dos docentes buscarem diferentes estratégias de ensino, apresentam um baixo a médio conhecimento sobre deficiência visual. Desse modo, discutimos sobre a importância e necessidade de investimentos em formação inicial e continuada para docentes.
Типы социально-психологической компетентности подростков с ограниченными возможностями здоровья: от адаптивности до дезадаптивности
Authors: Королева Юлия А.
Published: February 2025

Introduction. In the conditions of modern digital society, the research of socio-psychological competence of adolescents with disabilities (AWD) is relevant. Socio-psychological competence determines the variable ability of a personality to adapt in interpersonal interaction. The novelty of the work lies in the development of a typology of socio-psychological competence of adolescents with disabilities taking into account the properties and degree of their adaptability. Methods. Adolescents with mild mental retardation (n = 84), adolescents with visual impairment (visually impaired) (n = 70) and adolescents with hearing impairment (hearing impaired) (n = 60) were recruited as respondents (n = 294). The control group included adolescents with normal development (n = 80). The studied parameters of socio-psychological competence - directions and types of reactions in a frustrating situation, self-esteem and level of pretensions, types of behaviour, social interest and others - were assessed by the method of expert evaluations and the projective method. The methods of factor and cluster analysis were used for statistical data processing. Results. On the basis of mathematical and statistical processing of the results of the empirical study, a typology of socio-psychological competence of adolescents was created taking into account the characteristics of adaptability-maladaptability of personality. The proposed typology includes four different types of competence: (1) adaptive type, (2) partially adaptive, (3) partially maladaptive, and (4) maladaptive type. Discussion of results. As a result of the study, it was proved that groups of adolescents with disabilities are heterogeneous in terms of the degree of adaptability-maladaptability, the presence and expression of personal resources, and the characteristics of social and psychological competence of adolescents in these groups are largely determined by the potential safety of the intellectual sphere in case of sensory disorders and intellectual weakness in case of mental retardation.
Оценка двигательного развития в дошкольном возрасте: обзор диагностического инструментария
Authors: Гаврилова Маргарита Н. , Чичинина Елена А. , Якушина Анастасия А.
Published: February 2025

Introduction. This paper reviews tools used in psychological research to assess motor development in preschool children. This review discusses the concepts of motor development in children, including the following four components of motor development: physical activity, physical fitness, fundamental movement skills, and motor competence. The study describes the instruments used to assess each of these components. Theoretical justification. Searching for research on the subject of the review was carried out using the Elibrary and ResearchGate information platforms, as well as Scopus and Web of Science databases of information analysis resources. Special attention has been paid to research over the last 10 years. This review examined instruments for assessing physical activity and physical fitness (hardware tools and the Prefit test), and also described the most common tools for assessing fundamental movement skills and motor competence, including Movement Assessment Test Battery for Children–2, Test of Gross Motor Development–2, Bruininks–Oseretsky test–2, Körperkoordinationstest für Kinder, Zurich Neuromotor Assessment. Discussion. This review enabled the systematization of the existing instruments for assessing motor development in preschool age and the comparison of their limitations and the requirements for implementation. According to analysis, the Movement Assessment Test Battery for Children–2 is the most convenient and informative tool to examine children in Russian kindergartens. This review is particularly important because it identifies and discusses the main areas of psychological research that apply the considered assessment tools. The prospects for further research using these instruments are described.
A oralidade em livros didáticos de língua portuguesa: uma análise sobre propostas de aplicabilidade
Authors:   , Noronha Leiliane Aquino
Published: February 2025

A abordagem da modalidade oral da língua vem se tornando constantemente objeto de indagações, sobretudo, quando se trata da sistematização do seu ensino. Logo, levando em conta a sua relevância e suas particularidades, entendemos que esta deve ser considerada também nos livros didáticos presentes nas salas de aula, tendo em vista a sua forte influência no contexto escolar. Desse modo, esta pesquisa objetiva investigar a abordagem da oralidade em livros didáticos de português, partindo da análise comparativa entre as propostas de aplicabilidade sobre a temática em coleções do Ensino Fundamental II (Anos Finais) e Médio aprovadas pelo Plano Nacional do Livro Didático - PNLD (2014, 2015, 2016 – 2015, 2016, 2017). Assim, para compor nossa base teórica, amparamo-nos, principalmente, em Bakhtin (2006), Bueno; Costa-Hubes (2015), Cruz (2012), Forte-Ferreira (2014), Mendes (2005), Marcuschi; Dionisio (2007). Para a construção dessa pesquisa, como corpus, analisamos duas coleções de livros didáticos - Português: linguagens dos autores William Cereja e Thereza Cochar, sendo 01 do Ensino Fundamental II (Anos Finais) e 01 do Ensino Médio. Para tanto, realizamos uma pesquisa de natureza qualitativa, exploratória e documental (MINAYO, 2009; LUDKE; ANDRÉ, 2014; GIL, 2002) tendo a análise dos dados constituída por meio do processo metodológico de descrição e comparação entre as atividades presentes nos diferentes livros didáticos de português. Logo, os resultados apontaram um reducionismo de informações sobre oralidade e gêneros orais; um equívoco quando se trata de um trabalho com a oralidade a partir de atividades de oralização da escrita; as orientações destinadas para as produções orais, em sua grande maioria, apresentaram uma concepção do gênero como algo estático e, além disso, foi possível constatar uma estagnação no processo metodológico das atividades, já que as abordagens no Ensino Médio evidenciam praticamente o mesmo processo do Ensino Fundamental II (Anos Finais). Portanto, as atividades analisadas demonstraram a necessidade de uma revisão do trabalho com a oralidade nos livros didáticos estudados, já que foi possível constatar uma alternância em seus propósitos, pois ora contemplam um trabalho efetivo com a língua oral, já em outras situações fica evidente a necessidade de uma reformulação das propostas destinadas para a abordagem da oralidade
O ensino da oralidade a partir da argumentação no gênero debate
Authors:   , Soares Juliana Gurgel
Published: February 2025

O estudo que aqui se apresenta está centrado na oralidade como objeto de ensino por meio do uso do gênero debate regrado, levando em conta aspectos e perspectivas da argumentação. Nosso objetivo é analisar de que maneira o ensino da oralidade pode ser sistematizado, mediante o uso do gênero debate regrado a partir do trabalho com técnicas argumentativas mais recorrentes no gênero, para, então, propor atividades para o ensino que possibilitem ao aluno o uso consciente da argumentação e lhe permita maior domínio de gêneros orais, como o debate. Na busca pelo alcance destas proposições, buscamos uma aproximação da Linguística de Texto e da Teoria da Argumentação com o Ensino, haja vista não existir uma única perspectiva teórica que contemple todas as nossas questões e nos permita chegar àquilo que objetivamos. Então nos amparamos principalmente em Marcuschi (2001a; 2008), Marcuschi e Dionísio (2007), Bueno (2009) para versar sobre a questão do ensino da oralidade; e na teoria da Nova Retórica (PERELMAN; TYTECA, 2014) como base para as discussões sobre argumentação. Desenvolvemos uma pesquisa de natureza qualitativa e documental (MINAYO, 2001; GIL, 2008; GODOY, 1995) e como percurso metodológico para o alcance de nossos objetivos, analisamos um debate político disponível no site YouTube.com enquanto gênero oral eminentemente argumentativo e em seguida executamos os procedimentos analíticos com base na Análise de Conteúdo (BARDIN, 1977). Os resultados do processo de análise demonstraram a existência de percalços no momento da produção do gênero debate e, assim como Forte-Ferreira (2014), elencamos categorias ao fim da análise dos dados: o preparo prévio; a gestão do tempo; o uso de recursos argumentativos; com base nelas elaboramos um plano de atividades que inclui uma proposta para a constituição de sociedades de debates na escola, motivados pelo referencial encontrado no trabalho feito pelo Instituto Brasileiro de Debates, como um caminho que pode ser percorrido para uma sistematização do ensino da oralidade através do gênero oral debate
Considerações acerca da leitura crítica de vídeos mashups do youtube
Authors:   , Carvalho Maria Regina Moura de
Published: February 2025

presente pesquisa tem por objetivo analisar como o trabalho com vídeos mashups
pode cooperar para a formação de alunos analistas críticos dos conteúdos, levando em
consideração os componentes de produção do remix AMV (Anime Music Video) e a
intertextualidade. Para tanto, a Pedagogia dos Multiletramentos (CAZDEN et al., 1996), os
estudos sobre remix (ERSTAD, 2008; LANKSHEAR; KNOBEL, 2007; MANOVICH, 2007;
NAVAS, 2010) e sobre intertextualidade (PIÈGAY-GROS, 2010) são a base teórica deste
trabalho. Para que essas bases teóricas ganhassem operabilidade metodológica, optamos por
desenvolver uma pesquisa documental, a qual possibilitou a análise dos aspectos estéticos
(conceito, efeitos e sincronizações) e da intertextualidade presentes em três vídeos mashups que
selecionamos no site YouTube, a partir dos seguintes critérios: buscamos vídeos que se
constituem em misturas de elementos de diversas fontes distintas para formar uma nova
composição e que tratassem da ética no serviço público brasileiro. A análise desses dados nos
autoriza a concluir que, nos três vídeos analisados, seus autores produzem, de forma jocosa,
uma crítica a pessoas que, segundo eles, feriram a ética no serviço público. Percebemos que o
conceito é o que orienta as escolhas de seleção dos efeitos e sincronizações. Verificamos
também que os três vídeos apresentam relações intertertextuais por derivação do tipo paródia.
Esse processo de análise na leitura de vídeos mashups conduz ao despertar da consciência
quanto às escolhas éticas e estéticas desses vídeos
Enhanced Warehousing Operations through Platform-driven Horizontal Collaboration between Service Providers and Customers
Authors: Cerçi Muge , Kazanç Hande Cansın , Soysal Mehmet , Belbag Sedat
Published: February 2025

Introduction

The study investigates the problem of customer assignments to existing warehouses within the scope of supply chain management, aiming to achieve cost savings and operational efficiency in warehouse operations. Specifically, the customer assignment problem is modeled under the assumptions of horizontal collaboration, utilization of a shared digital infrastructure, fair distribution, and cold chain logistics. These assumptions are applied within a framework consisting of clusters of service receivers and service providers.

Objective

This research aims to assess the impact of horizontal collaboration, common digital infrastructure, cold chain logistics, and fair income distribution assumptions on assignment problems under the title of warehouse management.

Methods

A decision support model is proposed for the assignment problem under the title of warehouse management. This model incorporates the key assumptions and operational parameters to optimize customer assignments under varying scenarios.

Results

The findings obtained from the study reveal that in the presence of horizontal collaboration among service providers, the costs of service providers are minimized, the demands of service receivers are met more, the profit obtained from service receivers increases, and the number of warehouses used increases. Under the assumption of fair distribution, it has been observed that cold warehouses contribute more to the total profit, in other words, the income obtained per volume of warehouses, since they generate more income compared to standard warehouses.

Conclusion

This study highlights the benefits of fostering horizontal collaboration and fair income distribution among supply chain actors through a shared online platform. The results underscore the potential for improving profit levels, meeting customer demands more effectively and optimizing warehouse utilization. These insights provide valuable guidance for decision-makers aiming to enhance supply chain efficiency and equity.
ENQUADRAMENTOS, TELEJORNALISMO E POLÍTICA: A DEMISSÃO DE SERGIO MORO DO MINISTÉRIO DA JUSTIÇA E SEGURANÇA PÚBLICA NO JORNAL DA RECORD
Authors: Silva Daniel Batista de Jesus da , Negrini Michele
Published: February 2025

A política é um tema que perpassa o cotidiano das sociedades e que faz parte da pauta telejornalística. No caso da demissão de Sérgio Moro do Ministério da Justiça e Segurança Pública, o Jornal da Record fez ampla cobertura ao fato. Assim, o foco deste artigo é analisar os enquadramentos construídos sobre o pedido de demissão do ex-ministro Sergio Moro nas edições do Jornal da Record de 24 e 25 de abril de 2020. Os procedimentos analíticos são norteados pela análise de conteúdo e os conceitos de enquadramento. Após a análise dos aspectos selecionados, excluídos e enfatizados, observou-se predominância do enquadramento de conflito, reforçando o embate entre os envolvidos.
Palavras-chave: telejornalismo; enquadramentos; Jornal da Record.
Abstract
Politics is a theme that permeates the daily life of society, and it is part of the television journalism agenda. In the case of the Sergio Moro resignation of the Ministry of Justice and Public Security, the Jornal da Record covered the fact extensively. Then, this paper's focus is to analyze the frames built about the resignation of former minister Sergio Moro on the Jornal da Record in the editions of April 24 and 25, 2020. The analytical procedures are guided by content analysis and the framing concepts. After analyzing the selected, excluded and emphasized aspects, a predominance of the conflict framework was observed, reinforcing the clash between those involved.
Keywords: television journalism; frames; Jornal da Record.
Resumen
La política es un tema que forma parte del día a día de las sociedades y que forma parte del programa de noticia. En el caso de la renuncia de Sergio Moro del Ministerio de Justicia y Seguridad Pública, el Jornal da Record hizo amplia cobertura al hecho. Así, el foco de ese artículo es analizar los encuadres construidos sobre la renuncia del exministro Sergio Moro en las ediciones del Jornal da Record del 24 y 25 de abril de 2020. Los procedimientos analíticos se guían por el análisis de contenido y los conceptos de encuadramiento. Después del análisis de los aspectos seleccionados, excluidos y enfatizados, se observó el predominio del marco de conflicto, reforzando el enfrentamiento entre los involucrados.
Palabras clave: telediario; encuadramientos; Jornal da Record.
The Remediation of Hexavalent Chromium Using Orange Peel Biosorbent from Industrial Effluents
Authors: Channa Muhammad Kashif , Waris Muhammad , Rahman Sultana , Shahani Ali Bahar
Published: February 2025

One major cause of aquatic pollution is the accumulation of heavy metal ions. This study shows the biosorption properties of orange peel for removing chromium (CrVI) from industrial wastewater at a laboratory scale. This study focused on the biosorption of CrVI using orange peel biosorbent (OPB) from aqueous solutions in the plastic industry (PI), textile and fabrics industry (TFI), chemical industry (CI), and food industry (FI). The total Cr contents in effluents of FI, CI, TFI and PI varied between 30.0-38.0, 23.0-27.0, 35.0-95.0 and 40.0-180 mg L-1, respectively. Understanding the physical and chemical characteristics of CrVI is necessary for successful bioremediation using OPB. The CrVI is bound to OPB (the peel of Citrus aurantium) by interactions with the biomass's amine and -CO functional group, according to the FT-IR spectra. The change in morphology of OPB was checked by scanning electron microscopy (SEM) after loading of CrVI, indicating that the bio-sorption of CrVI occurs on the OPB. From water samples at an ideal pH of 7, a contact period of 20 min, and a temperature of 298 K, the CrVI biosorption capacity of the biosorbent material was reported to be 0.222 mmol/g (48.0 mg/g). The results show that OPB can be used as an adsorbent or stabilizer for CrVI from industrial effluents.
Evaluating the Knowledge Level, Practice, and Behavioral Change Potential of Care Managers in Pressure Injury Prevention Using a Mobile App Prototyping Model in the Home-Care Setting: Single-Arm, Pre-Post Pilot Study
Authors: Kohta Masushi , Takahashi Mayumi , Koyanagi Hiroe , Sugama Junko
Published: February 2025

Background

The use of mobile apps to promote knowledge level, practice, and behavioral change potential has become increasingly common. However, studies on apps targeting social welfare employees working in the home-care setting to prevent pressure injury (PI) are lacking. The care manager (CM) plays a key role in connecting the demand and supply of home-care services. PI is more prevalent in the home-care setting, where resources are limited, than in acute settings.

Objective

The research hypothesis was that CMs who use a mobile app will have improved general knowledge and heightened practice for PI prevention, compared to that before using the app. This study aimed to assess the effectiveness of a PI prevention support mobile app prototyping model (Pips-Map) in improving the knowledge level, practice, and behavioral change potential of CMs in PI prevention in the home-care setting.

Methods

This was conducted between December 2021 and December 2023 as a single-arm, pre-post pilot study including 27 CMs who worked in a Japanese city. Pips-Map was used for 6 months in daily practice, and a self-administered test questionnaire was used to assess participants’ knowledge and practice in PI prevention before or after using Pips-Map. At the end of the posttest, a validated App Behavior Change Scale was used to analyze behavioral change potential. This study followed the Consolidated Standards of Reporting Trials (CONSORT) extension to pilot and feasibility trials.

Results

In total, 19 participants were analyzed. Out of 55 points, the total mean knowledge score significantly increased from 30.9 (SD 5.9) in the pretest group to 36.1 (SD 5.9) in the posttest group (P=.0003). The number of participants with a total score of >70% (adequate knowledge level) increased from 2 (11%) to 7 (36.8%), but the difference was not statistically significant (P=.07). For the level of practice, out of 21 points, the total score increased from 15.2 (SD 3.1) in the pretest group to 16.2 (SD 3.0) in the posttest group, but no statistically significant differences were observed (P=.16). The behavior change scale revealed that participants positively evaluated the Pips-Map to provide information on PI prevention guidelines but had concerns regarding inadequate usability and financial incentives of Pips-Map.

Conclusions

The use of Pips-Map for 6 months in actual practice increased the knowledge level of Japanese CMs in PI prevention, but it did not change the level of practice. Considering the need for updating apps that aim to promote behavioral change, this study identified some limitations of Pips-Map. Thus, revisions must be made to adapt Pips-Map to home-based care needs.
Development and Validation of a Machine Learning Algorithm for Predicting Diabetes Retinopathy in Patients With Type 2 Diabetes: Algorithm Development Study
Authors: Kim Sunyoung , Park Jaeyu , Son Yejun , Lee Hojae , Woo Selin , Lee Myeongcheol , Lee Hayeon , Sang Hyunji , Yon Dong Keon , Rhee Sang Youl
Published: February 2025

Background

Diabetic retinopathy (DR) is the leading cause of preventable blindness worldwide. Machine learning (ML) systems can enhance DR in community-based screening. However, predictive power models for usability and performance are still being determined.

Objective

This study used data from 3 university hospitals in South Korea to conduct a simple and accurate assessment of ML-based risk prediction for the development of DR that can be universally applied to adults with type 2 diabetes mellitus (T2DM).

Methods

DR was predicted using data from 2 independent electronic medical records: a discovery cohort (one hospital, n=14,694) and a validation cohort (2 hospitals, n=1856). The primary outcome was the presence of DR at 3 years. Different ML-based models were selected through hyperparameter tuning in the discovery cohort, and the area under the receiver operating characteristic (ROC) curve was analyzed in both cohorts.

Results

Among 14,694 patients screened for inclusion, 348 (2.37%) were diagnosed with DR. For DR, the extreme gradient boosting (XGBoost) system had an accuracy of 75.13% (95% CI 74.10‐76.17), a sensitivity of 71.00% (95% CI 66.83‐75.17), and a specificity of 75.23% (95% CI 74.16‐76.31) in the original dataset. Among the validation datasets, XGBoost had an accuracy of 65.14%, a sensitivity of 64.96%, and a specificity of 65.15%. The most common feature in the XGBoost model is dyslipidemia, followed by cancer, hypertension, chronic kidney disease, neuropathy, and cardiovascular disease.

Conclusions

This approach shows the potential to enhance patient outcomes by enabling timely interventions in patients with T2DM, improving our understanding of contributing factors, and reducing DR-related complications. The proposed prediction model is expected to be both competitive and cost-effective, particularly for primary care settings in South Korea.
Clinical Improvements from Telemedicine Interventions for Managing Type 2 Diabetes Compared to Usual Care: A Systematic Review, Meta-Analysis, and Meta-Regression (Preprint)
Authors: Jiang Shujie , Gao Xianru , Diao Haiqing , Zhang Yang , Lu Guangyu , Liu Xiaoguang , Li Yuping
Published: February 2025

BACKGROUND

Background: Type 2 diabetes mellitus (T2DM) is a prevalent chronic metabolic disorder that poses substantial challenges to global healthcare systems and patient management. Telemedicine, defined as the use of information and communication technologies to enhance healthcare delivery, has emerged as a potential tool to improve access to care and facilitate the management of T2DM.

OBJECTIVE

Objective: This systematic review and meta-analysis aimed to evaluate the clinical effectiveness of various telemedicine interventions compared to usual care in glycemic control, body weight, and cardiovascular health in adults with T2DM.

METHODS

Methods: A comprehensive literature search was conducted across databases such as PubMed, Cochrane Library, and Web of Science for randomized controlled trials (RCTs) published up to 23 August 2024. Eligible RCTs compared telemedicine interventions with usual care in adults with type 2 diabetes. The primary outcome assessed was HbA1c levels, while the secondary outcomes included mean glucose, fasting blood glucose (FBG), body mass index (BMI), weight, systolic blood pressure (SBP), diastolic blood pressure (DBP), high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c). Data were extracted and analyzed using a random-effects model, and meta-regression was performed to explore potential moderators.

RESULTS

Results: A total of 58 RCTs, encompassing 13,942 participants, were included in the analysis. Our findings showed that telemedicine interventions significantly improved HbA1c levels compared to usual care (MD = -0.38; 95% CI = -0.49, -0.27; Z = 6.94; P < 0.01), despite high heterogeneity (I² = 96%). Subgroup analyses revealed that telemedicine delivered by physicians, dietitians, and researchers achieved the most significant reductions in HbA1c levels. Furthermore, short-term and long-term interventions showed significant HbA1c improvements, while medium-term interventions did not achieve statistical significance. Evidence for effects on FBG, mean glucose, blood pressure, and cardiovascular health management was less conclusive compared to HbA1c but showed potential in some included studies.

CONCLUSIONS

Conclusion: This review highlights telemedicine's superior effectiveness over usual care in improving HbA1c levels in patients with T2DM, regardless of the type of intervention. Telemedicine led by physicians, dietitians, and researchers showed the greatest efficacy in managing blood glucose levels. Furthermore, telemedicine interventions show promise for monitoring weight and cardiovascular health in patients with T2DM.

CLINICALTRIAL

PROSPERO International Prospective Register of Systematic Reviews CRD42024608130.
The impact of point of care testing for influenza on antimicrobial stewardship (PIAMS) in UK primary care: mixed methods study (Preprint)
Authors: Hoang Uy , Smylie Jessica , Button Elizabeth , Macartney Jack , Okusi Cecilia , Byford Rachel , Ferreira Filipa , Xie Charis , Joy Mark , Clark Tristan , de Lusignan Simon
Published: February 2025

BACKGROUND

Influenza and respiratory syncytial virus (RSV) predominantly circulate during the winter season and cause acute respiratory infections (ARI). Deploying molecular point-of-care testing (POCT) in primary care at can inform whether a patient presenting with an ARI has influenza or RSV. An early virological diagnosis, could facilitate appropriate use of antivirals and enable better antimicrobial stewardship.

OBJECTIVE

To report the impact of POCT for influenza and RSV on antimicrobial prescribing including antiviral therapy in primary care.

METHODS

The impact of POCT for influenza on antimicrobial stewardship (PIAMS) in UK primary care was an observational study undertaken 20th Jan–31st May 2023, in practices that contribute data to the English sentinel network. People presenting with ARI had nasopharyngeal swab performed and were tested for Influenza and RSV with a molecular POCT analyser located within the practice. Data on antimicrobial prescribing and other study outcomes were collected by linking information from the analyser to coded data from the patient’s computerised medical record (CMR).

RESULTS

In total 323 swabs were collected from ten PIAMS study practices. 59.7% (197/323) of swabbed patients were female, and the mean age was 37 years. 2.79% (9/323) of all swabs were positive, with 0.31% (1/323) positive for influenza A, 1.55% (5/323) postivie for influenza B and 0.93% (3/323) positive for RSV.

In total 80 patients were prescribed antibiotics seven days following POCT testing. There were no instances of antiviral prescribing in the seven days post-testing. The odds ratio for antibiotic prescribing given a positive POCT result was 1.54 (95% CI: 0.38–6.30; P =0.55) compared with a negative test.

CONCLUSIONS

This study illustrates the risk of having a narrow study window, our observation period was not aligned with when influenza was circulating. The peak of weekly incidence of influenza in the sentinel network was in the last week of 2022, and RSV circulating prior to this. Further evidence is needed to assess the impact of POCT on antibimicrobial prescribing. The viruses tested for using POCT could be aligned with the circulating viruses identified by the sentinel network.

CLINICALTRIAL

Not applicable

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/46938
"The Use of AI Chatbot Therapy as a Stress Management Intervention In Non-Clinical Populations": An Experimental Study (Preprint)
Authors: Carlos Alqueen , Dela Peña Sheila Marie
Published: February 2025

BACKGROUND

Mental health concerns are rising in the Philippines, yet access to psychological services remains limited due to a shortage of mental health professionals and financial barriers. AI chatbot therapy presents a potential solution by providing accessible and scalable mental health support. While previous research has explored AI chatbots in clinical populations, their effectiveness in stress management among non-clinical populations remains underexplored.

OBJECTIVE

This study aims to evaluate the effectiveness of AI chatbot therapy in reducing perceived stress among non-clinical populations. Specifically, it examines whether AI chatbot therapy significantly decreases stress levels compared to a control group.

METHODS

An experimental pretest-posttest design was utilized. A total of 100 undergraduate students from Metro Manila (aged 18-25) were randomly assigned to either the intervention group (n=50), which used AI chatbot therapy for 40 minutes to 1 hour daily over seven days, or the control group (n=50), which did not receive the intervention. Stress levels were measured using the Perceived Stress Scale (PSS) before and after the intervention. Statistical analyses, including paired and independent t-tests, were conducted to compare within-group and between-group differences.

RESULTS

The intervention group demonstrated a significant reduction in stress levels from pre-test (M = 31.36, SD = 4.25) to post-test (M = 20.86, SD = 5.10), with a large effect size (Cohen’s d = 2.43, p < .001). The control group also showed a reduction in stress (M = 32.00, SD = 4.17 to M = 24.20, SD = 8.65), but with a smaller effect size (Cohen’s d = 0.96, p < .001). A comparison of post-test scores between groups revealed a statistically significant difference (p = .021), favoring the intervention group.

CONCLUSIONS

The findings suggest that AI chatbot therapy is an effective stress management tool for non-clinical populations, demonstrating significant reductions in perceived stress. Given the accessibility and scalability of AI chatbots, they hold promise as a supplementary mental health intervention, particularly in resource-limited settings. Further research should explore long-term effects, usability across diverse populations, and integration with traditional mental health care.
Antioxidant Activity and Quality of Frozen Yoghurt with Moringa oleifera Lamk. Leaves Extract
Authors: Sari Primaningrum Dian Indah , Swasti Yuliana Reni , Purwijantiningsih Ekawati
Published: February 2025

Moringa oleifera Lamk. (Moringa) is a plant widely distributed across various regions in Indonesia. The leaves of Moringa oleifera Lamk. contain higher nutritional value in protein and minerals compared to the green vegetables that are commonly consumed. This plant can be used to improve the quality of frozen yoghurt, a functional food that is currently popular due to the existence of Lactic Acid Bacteria (LAB), which is good for digestion. Therefore, this research aimed to improve the nutritional quality of frozen yoghurt using Moringa oleifera Lamk. Leaves Extract (MOLE), which is high in antioxidants and protein. However, MOLE does not reduce the viability of LAB. The viability of LAB decreases when phytochemical content with the ability as an antibacterial is added. The soluble fiber content of MOLE is able to improve the texture of frozen yoghurt. In this research, four different frozen yoghurt samples were produced with the addition of MOLE in various ratios (0%, 10%, 20%, and 30%). The analysis shows that frozen yoghurt with 30% MOLE produces the highest antioxidant activity and viability of probiotics. The content of product with 30% MOLE includes 2.85±0.13% fat, 10.07±0.44% protein, 1.10±0.01% ash, 26.4±0.35% total solid (TS), 21.67±0.58% total soluble solid (TSS), 78.66±1.31% overrun, 807±5.77 (s) melting rate, 0.86±0.02% titratable acidity, and 5.4±0.02 pH. It also contains 8.58±0.52 log CFU/mL LAB, Salmonella negative/25 g, 102.26±0.13 mg GAE/100 mL of total phenolic, and 87.78±0.64% of antioxidant activity.
Effect of Withering and Drying Process of Cemara Udang (Casuarina equisetifolia) Leaves to Functional Herbal Tea
Authors: Handarini Kejora , Rahmiati Retnani , Yuniati Yuyun
Published: February 2025

The industry is intensively producing health product from herbal plants to combat free radicals and prevent the potential of cancer disease in the body. In Indonesia, Cemara Udang (Casuarina equisetifolia) leaves have been investigated as herbal tea product for antioxidant purposes as a free radical scavenger from various plants. This herbal tea requires significant attention during processing to produce a quality final product. Therefore, this research aimed to examine the effect of setting withering times of 14 and 16 hours, along with a drying temperature of 40 and 50 °C on cemara udang leaves. Product quality was evaluated based on the chemical components and nutritional characteristics of tea, such as moisture content, pH, antioxidant activity, total phenolic content, and vitamin C, as well as sensory aspects. The evaluation was carried out based on the degree of preference for color, aroma, and taste. Fresh cemara udang samples had 46.57% moisture content, pH 7.05, 131.53 µg/mL IC50 value, 1.53 mg/100 g total phenolic, and 43.46% vitamin C. Based on the degree of preference, color, flavor, and taste hedonic score had 3.11, 2.57, and 1.94 out of 7.00, respectively. Tea of cemara udang that was withered for 16 hours and dried at 50°C showed good quality stability with favorable sensory attributes. This varies significantly compared to the control, with 10.32% moisture content, pH 7.04, 137.94 µg/mL IC50 value, 1.2 mg/100 g total phenolic, and 29.26% vitamin C. Furthermore, color, flavor, and taste hedonic scores had 6.37, 6.03, and 6.27 out of 7.00, respectively.
Virtual Reality in Manufacturing Planning and Operations
Authors: Tanbour Emad , Greenfield M. C. , Alzuad Hawra
Published: February 2025

Abstract: Today’s business environment is dominated by unpredictable changes and uncertainty, there is a need for reducing
cost and improving quality within the realm of manufacturing. These challenges have forced companies to turn to new and
emerging technologies such as virtual reality (VR). Virtual reality is being used in manufacturing planning and operations as a
helpful technology to achieve rapid consolidation of information and decision-making through visualization and experience. In
this paper, 23 articles relevant to past and current virtual reality’s application to manufacturing were discussed and analyzed.
Future virtual reality ventures and applications for manufacturing are discussed.
Living Hadith in the Peu Intat Ritual: Sacredness and Cultural Adaptation in the Death Tradition of the Teunom Community, Aceh Jaya
Authors: M. Jakfar Tarmizi
Published: February 2025

The Peu Intat ritual in the Teunom community of Aceh Jaya represents a localized form of Living Hadith, where prophetic traditions are actively preserved and practiced within a socio-cultural framework. This study examines Peu Intat as an applied interpretation of hadith and explores its social, theological, and cultural functions. Using a qualitative approach with the Living Hadith framework, data were collected through interviews, participant observation, and document analysis involving religious scholars, community leaders, and local residents. The findings reveal that Peu Intat serves three key functions: (1) strengthening community and familial solidarity, (2) reinforcing faith by guiding the dying person to recite kalimat tauhid, and (3) integrating hadith into local traditions, reflecting the adaptability of Islamic teachings. This study confirms that Living Hadith is not merely textual transmission but a dynamic process shaped by local contexts.
Folketingsvalget 2019: Grønnere holdninger blandt de unge, men også et klima- og miljøvalg på tværs af aldersgrupper
Authors: Kongshøj Kristian
Published: February 2025

Folketingsvalget 2019 er blevet udråbt til et klimavalg, hvor holdninger til miljø og klima fik afgørende betydning for krydset. Der har samtidig været fokus på de unges rolle som særligt mobiliserede. Med udgangspunkt i YouGovs spørgeskema fra 2019-valget (respondenter udtrukket fra stående onlinepanel) undersøges, hvorvidt de unge adskilte sig tydeligt ved et valg, hvor der samtidig var større folkelig opbakning til dagsordenen end nogensinde før. Artiklen undersøger sammenhængen mellem holdninger til klima/miljø og partivalg på tværs af tre forskellige aldersgrupper (18-34, 35-64 og 65+ år). Disse diskuteres teoretisk med udgangspunkt i kohorteperspektivet og postmaterialisme. Der skelnes både imellem issuesaliens og issueprioriteringer, og der kontrolleres for holdninger på andre vigtige politikområder. Selvom de unge generelt har lidt grønnere holdninger, er sammenhængen med partivalg ikke stærkere for de unge. I stedet er billedet, at holdninger til klima ogmiljø spillede en betydelig rolle for den brede befolknings partivalg uanset aldersgruppe. Der er dog en tydelig tendens til, at de yngre klima- og miljøbevidste vælgere fravælger Socialdemokratiet til fordel for de øvrige partier på venstrefløjen eller Radikale Venstre, mens politikområdet i højere grad synes at kunne trække vælgere til regeringspartiet blandt de ældre aldersgrupper.
Comparative morphological parameters of the reproductive organs of Amur tiger females
Authors:   Primorskaya State Agricultural Academy, Korotkov Evgeniy A. , Lyubchenko Elena N. ,   Primorskaya State Agricultural Academy, Korotkova Irina P. ,   Primorskaya State Agricultural Academy, Zhilin Ruslan A. ,   Primorskaya State Agricultural Academy, Kozhushko Aleksandr A. ,   Primorskaya State Agricultural Academy, Kapralov Dmitriy V. ,   Primorskaya State Agricultural Academy
Published: February 2025

Preservation of the gene pool of animals and plants and, above all, rare and endangered
species is one of the main tasks of environmental protection and international efforts in this area. Today, there are many different programs, the actions of which are focused on the preservation
of the population and the study of diseases of the Amur tiger. The study of internal organs, in
particular, the features of the female genital organs, is timely and relevant, since their morphological
and functional state affects the reproduction and effective adaptation of populations to habitat
changes. Some scientists have studied the internal organs of large wild felines, including the Amur
tiger. However, morphometric changes in the genitals of female Amur tigers in the comparative
age aspect have not been studied. In the course of the morphometric studies, it was found that
body weight, in contrast to body length, in female Amur tigers increased rapidly from the age of
six months to one and a half years. The left ovary, like the left uterine horn, is larger in all female
Amur tigers of different ages. The length of the body of the uterus and ovaries, the relative length
of the complex of reproductive organs to body length increased more intensively from the age of
six months of females to one and a half years, and less actively – from one and a half to three years
of age. This indicates a significant increase in the body length and internal reproductive organs of
female Amur tigers from the age of six months to one and a half years.
The effectiveness of the use of balancing feed additives from non-traditional feed products in replacement heifers feeding
Authors:   Far Eastern State Agrarian University, Tuaeva Evgeniya V.
Published: February 2025

The current stage of development of cattle breeding is characterized by increasing
demands for a quantitative increase in production, improvement of its quality and cost reduction.
The Amur region belongs to the biogeochemical region with a deficiency in the agrosphere of all standardized microelements. In this regard, the problem of providing adequate nutrition for animals,
including cattle, should be addressed through the production of balancing feed additives. In
the conditions of theregion, it is possible to use feed additives made from natural feed resources
in animal feeding as a source of biologically active substances. These can be red anfeltia alginates
and dihydroquercetin. In order to study this issue, scientific, economic and physiological
experiments were carried out in the conditions of LLC “Priamurye”. To achieve the set goals and
objectives, three groups of clinically healthy replacement heifers of the red-and-white breed at the
age of 10 months, 10 heads each, were formed according to the principle of analogues. Higher
rates of average daily gain were obtained in the second experimental group, where heifers received
red ahnfeltia alginates together with dihydroquercetin instead of premix P 62-1. When analyzing
the exterior, the replacement heifers of the control group were inferior to their herdmates by the
main measurements of height at the withers and rump, depth and width of the chest, girth of the
chest behind the shoulder blades, oblique length of the body, width in makloks and girth of the
metacarpus. It has been established that the inclusion of experimental additives in the diet, which
contain normalized microelements in organic form, contributed to an increase in the digestibility
of dietary nutrients in animals of the experimental groups. The use of normalized microelements in
organic form as part of non-traditional feed resources in diets for cattle contributes to a significant
increase in growth, the development of replacement young animals, and the intensity of metabolic
processes.