bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential application of laser-based imaging technology in the quality evaluation of agricultural products : A review
Authors: Sanchez Philip Donald Cabuga , HASHIM NORHASHILA , SHAMSUDIN ROSNAH , MOHD NOR MOHD ZUHAIR
Published: November 2020

Non-destructive quality evaluation of agricultural products particularly during postharvest stage has been a primary concern in recent years. The laser-based imaging technology is one of the most promising non-invasive tools which demonstrate potential ability to replace the conventional methods of quality monitoring that are time-consuming, expensive, laborious, inaccurate and most of all destructive. Hence, in this paper, we briefly reviewed the potential application of laser-light backscattering imaging technique (LLBI) as a non-destructive quality evaluation tool applied in agricultural products. This review mainly reports the current knowledge on the successful implementations of the LLBI in measuring the various quality-related attributes of agricultural products under different postharvest conditions such as in drying, storage, sorting, maturity identification, defect detection, etc. The basic components, uses and considerations of the technique are highlighted in this paper. Moreover, the advantages, drawbacks, measurement methods, data analysis applied as well as the accuracies obtained are briefly summarized.
Acompañamiento de Estudiantes con Discapacidad Auditiva en la Escuela de Ciencias Psicológicas USAC
Authors: Ureta Morales Francisco José , Alvarez Garcí­a Gabriela , Parada Doris Melissa , Mencos Marí­a Alejandra
Published: November 2020

La Escuela de Ciencias Psicológicas de Universidad de San Carlos de Guatemala (USAC) creó el Proyecto de Ejercicio Técnico Supervisado (ETS) y Ejercicio Profesional Supervisado (EPS) para que estudiantes de la carrera puedan ser Facilitadores Avanzados de lengua de señas y, acompañen a estudiantes con discapacidad (ECD) como una opción de graduación. El objetivo general del proyecto es promover la educación inclusiva que permita a los ECD un adecuado proceso de aprendizaje y el desarrollo de las competencias como futuros psicólogos; el proyecto se basa en el modelo social de la discapacidad y entre sus principales logros está ampliar la cobertura de atención, ya que la intérprete contratada no lograba cubrir todas las clases, generar accesibilidad en los procesos de enseñanza y aprendizaje, realización de talleres de concientización con personal administrativo, grabación de videos en lengua de señas e investigación sobre discapacidad en la educación superior. Como desafí­os aumentar el lenguaje técnico en señas y disposición de docentes para realizar los ajustes razonables.
Derechos Humanos, Educación y Aprendizaje Estratégico
Authors: Aldana Rabanales Karla Irene
Published: November 2020

El presente ensayo aborda la educación como Derecho Humano fundamentado en la dignidad de la persona. Cada persona, está en constante proceso de aprendizaje, un aprendizaje que debe ser idealmente estratégico y autónomo, para lograr el desarrollo integral que un ser humano es capaz de alcanzar y dar así­ cumplimiento a los Derechos Humanos.

Para comprender el aprendizaje estratégico, es imperativo describir las estrategias de aprendizaje y centrarse en procesos cognitivos superiores. El aprendizaje es un acto cotidiano, evidente en procesos como leer y escribir, siendo éstos, entre otros, los que nos permitirán valorar la educación como un Derecho Humano inalienable.

Se propone como conclusión que el generar un ambiente de aprendizaje estratégico y autónomo, enmarcado en los Derechos Humanos es el escenario idóneo de la educación. Conclusión que pretende abrir un espacio a la reflexión, el análisis y la exploración de los constructos aquí­ abordados.
SEASONAL CHANGES OF MOLLUSCA TAXOCENE ON SOFT SEDIMENTS IN THE RIVER-SEA CONTACT ZONE AT THE MOUTH OF THE CHERNAYA RIVER AND CORNER PART OF THE SEVASTOPOL BAY (SOUTH-WESTERN CRIMEA)
Authors: Makarov M. V.
Published: November 2020

The seasonal dynamics of species composition, abundance and biomass of mollusks in contact zone of the river and simultaneously in the mouth of the river Chernaya and in the corner part of the Sevastopol bay was analyzed for the first time. The distribution of molluscs depending on salinity was researched. As the river flows into the Bay, the number of species, abundance and biomass increased. In the Chernaya river the factor of salinity plays more important role for distribution of Mollusca than temperature. In this area the Mollusca taxon includes 22 species belonging to 3 classes: Polyplacophora, Bivalvia and Gastropoda. The largest number of species is recorded in October, May and August, the smallest — in winter months. In 2006-2007, the quantitative indicators (number and biomass) were also in average quite high in the study area compared to the corner part of the Sevastopol Bay. The gastropod Hydrobia acuta is a dominant species in terms of abundance, and the bivalve Cerastoderma glaucum in terms of biomass. The seasonal maximum number of Mollusca is confined to the warm period (late spring – summer), the minimum to the cold (late autumn – winter), which is due to the predominance of thermophilic species in this area. The maximum seasonal dynamics of shellfish biomass was observed in summer; the minimum was registered in spring. The trophic structure of the Mollusca taxon was determined. It was very diverse and included 6 groups, with a predominance of phytophages, detritophages and sestonophages.
MELITTOPHILIC COMPLEX OF PLANTS PROVIDING FORAGE BASE FOR HONEY BEES (APIS MELLIFERA) IN THE MOUNTAIN-FOREST ZONE OF CRIMEA
Authors: Bykova T. O. , Ivashov A. V. , Ivanov S. P. , Sattarow W. N. , Vahrusheva L. P.,
Published: November 2020

For the first time, in the mountain-forest ecosystems of Crimea of parcel organization level adjacent to the beehives of honey bees (Apis mellifera L.), a species composition of plants representing the melittophilic complex has been identified which provides honey bees with pollen and nectar during the entire warm season. The complex includes 57 species of plants where the honey bees that collect pollen or nectar have been registered. The core of the melittophilic complex consisted of 35 species of plants, the proportion of simultaneously flowering (in any period of the season) flowers of each one exceeded 2.5 % of the total number of flowers of all flowering species at this time. In early spring, the list of such species included 15 plant species belonging to 14 genera and 12 families. In this period, the decisive forage value (species whose flower share exceeded 10 % of all flowering flowers) was represented by 4 plant species: Cornus mas L., Corylus avellana L., Dentaria quinquefolia M. B. and Prunus divaricata Ledeb., the important value (the flowers share made <10 %, but >2.5 %) had 4 species: Ficaria verna Huds., Galanthus plicatus M. Bieb., Primula vulgaris Huds. and Scilla bifolia L. In spring, the forage base made up 20 plant species belonging to 18 genera and 7 families. Four species had decisive forage value: Cerasus avium L., Malus sylvestris L., Prunus spinosa L. and Pyrus elaeagrifolia Jacq., 7 species had important value: Crataegus monogyna Jacq., Fragaria vesca L., Lamium purpureum L., Crepis pulchra L., Prunus domestica L., Thlaspi arvense L. and Trifolium ambiguum M. Most of the species belonged to the Rosaceae family (10 species). In summer period, the forage basis comprised 20 species of melittophilic plants belonging to 19 genera and 9 families. 5 species had decisive value: Cichorium intybus L., Cirsium arvense (L.) Scop., Echium vulgare L., Medicago sativa L. and Trifolium ambiguum M., the important value had 7 species: Achillea millefolium L., Betonica officinalis L., Ballota nigra L., Centaurea diffusa Lam., Clematis vitalba L., Linaria vulgaris Mill. and Onobrychis sativa Lam. The representatives of the Asteraceae family (7 species) dominated; the representatives of Fabaceae (5 species) and Lamiaceae (4 species) also played a significant role. In autumn, there were the following food sources for honey bees: Diplotaxis tenuifolia (L.) DC., Centaurea diffusa Lam., Erýngium campéstre L., Carduus crispus L., and on the steppe slopes of the mountains: Scilla autumnalis L. and Crocus speciosus M. B. It has been established that the greatest number of melittophilic plant species in the studied mountain-forest biogeocenoses grow on parcels of forest edges and glades, steppe slopes of the mountains in their natural state. Oak-hornbeam and floodplain tree-shrub parcels have a smaller variety of species, but are essential for bees in early spring and spring..
QUALITY OF LIFE PROBLEMS OF GYNECOLOGICAL CANCER PATIENTS
Authors: Churuksaeva Olga , Kolomiets Larisa
Published: November 2020

Due to improvements in short- and long-term clinical outcomes a study of quality of life is one of the most promising trends in oncology today. This review analyzes the published literature on problems dealing with quality of life of patients with gynecological cancer. Data on quality of life with respect to the extent of anticancer treatment as well as psychological and social aspects are presented. The relationship between quality of life and survival has been estimated.
EFFECTIVENESS OF PUNCTURE BIOPSIES OF THE PANCREAS UNDER ULTRASOUND GUIDANCE
Authors: Mikhetko Alla , Zakharov Dmitriy , Perov V. , Belova I.
Published: November 2020

The results of 205 puncture biopsies of solid and cystic pancreatic lesions performed in 202 patients at the Republican Oncological Dispensary of the Republic of Karelia for a 7-year period (2009-2015) are presented. Informative material for morphological investigation was obtained in 95.5% of cases. A comparison of results of cytological examination of the material from 56 patients with pancreatic lesions with histological data was carried out. The efficiency of the cytological method was 90.6%, sensitivity - 87.8%, specificity - 100%. To determine histological form of tumor in cytological examination of the material of the pancreas was successful in 82.1% of cases.
EXPERIMENTAL STUDY OF THE EFFICACY OF L-LYSINE-A-OXIDASE TRICHODERMA CF. AUREOVIRIDE RIFAI ON MODELS OF XENOGRAFTS OF HUMAN TUMORS IN ATHYMIC MICE AND EVALUATION OF SYNERGISM WITH CISPLATIN OR TOPOISOMERASE INHIBITORS
Authors: Pokrovskiy Vadim , Lukasheva Yelena , Chernov Nikolay , Treshchalina Yelena
Published: November 2020

The effectiveness of L-lysine-alpha oxidase Trichoderma cf. Aureoviride Rifai BKMF-4268D (LO) on models of subcutaneous xenografts of human tumors in athymic mice as well as the effectiveness of combination therapy with known antitumor drugs: cisplatin, irinotecan, etoposide on models of P388 lymphocytic leukemia, Lewis lung (LLC) and B16 melanoma was evaluated. The intraperitoneal injection of LO in a discrete regime at doses of 150-75-75-75-75 E/kg demonstrated inhibition of growth of all studied xenografts of human tumors in athymic mice. The combination of irinotecan+LO on the LLC model gave a significant summative therapeutic benefit with an increase in mouse life expectancy up to 35%. Cisplatin and LO realized a significant (p
PRELIMINARY RESULTS OF COMPLEX TREATMENT OF BREAST CANCER PATIENTS INCLUDING RECONSTRUCTIVE-PLASTIC SURGERY, CHEMOTHERAPY AND CONFORMAL RADIOTHERAPY
Authors: Tkachev Sergey , Nazarenko Aleksey , Sobolevskiy Vladimir , Trofimova Oksana , Ivanov Stanislav , Glebovskaya Valeriya , Borisova Tatyana , Khaylenko Viktor , Timoshkina Ye.
Published: November 2020

Preliminary results of complex treatment of 58 patients with I-IIIC breast cancer (T1-4N0-3M0) who underwent radical mastectomy with reconstruction of the breast in its various variants and conformal radiotherapy in adjuvant mode to the pectoral region and regional lymph drainage are presented in the article. A low incidence of complications from the reconstructed breast was noted: two (7 %) cases of implant removal due to pronounced capsular contracture and in connection with infection of the implant bed. At the time of observation of patients from 11.5 to 158.9 months, median 18.6 months, in 3 (5 %) patients clinically significant radiation pulmonitis was detected. The overall two-year survival was 97 % and progression-free survival was 90 %. In 6 (10 %) patients distant me-tastases were detected, in 1 (2 %) - recurrence of the disease in the area of postoperative scar. Thus reconstructive-plastic surgery can be an integral part of complex anti-tumor treatment including radiotherapy with direct indications to it in full volume and dose.
AUTONOMIC TONUS REGULATION DISORDERS IN RATS WITH A TRANSPLANTED TUMOR PC-1
Authors: Krylov Vasiliy , Lobkaeva Yevgeniya , Fedotov Vasiliy , Oshevenskiy Leonid , Shabalin Mikhail
Published: November 2020

By means of analysis of the heart rate variability method (HRV) it was discovered that the HRV rates (total capacity of the Tp spectrum, the squared deviation SDNN, high-frequency component HF) of the rats, which had the implanted tumor PC-1 were decreasing in comparison with the control group (the rats without a tumor), which indicated a significant sympathizing of the vegetal tonus. The use of stress-tests (the orthostatic test, short-term immobilization) led to statistically significant variation of HRV rates, which also differed from the control group. It was demonstrated that the low-frequency components LF of the spectrum of the tumor-bearing animals decreased in response to functional stress, which signified the disorder of tonus regulation in autonomic nervous system, i.e. the changing of sympathizing over to parasympathizing, the breakdown of adaptive response.
SURGICAL CORRECTION OF POSTOPERATIVE INTRAABDOMINAL COMPLICATIONS IN PATIENTS WITH COLORECTAL CANCER
Authors: Topuzov Eskender , Yerokhina Yelena , Topuzov Eldar , Drogomiretskaya Yelena , Balashov Vyacheslav , Kislitsina O.
Published: November 2020

The results of treatment of postoperative intraabdominal complications in patients who underwent surgical interventions for colon cancer were studied. The effect of the re-operation time was assessed. The volume of surgical correction was discussed in case of insufficiency of anastomosis sutures. The results of the study made it possible to identify the most rational timing and scope of surgical correction of postoperative intraabdominal complications in patients with colorectal cancer.
IMPROVEMENT OF CERVICAL CANCER SCREENING USING DETERMINATION OF MICRORNA IN CYTOLOGICAL PREPARATIONS
Authors: Bakhidze Yelena , Malek Anastasiya , Mikhetko Alla , Ivanov Mikhail , Samsonov Roman , Berlev Igor , Arkhangelskaya P.
Published: November 2020

The sensitivity of cytological screening of cervical cancer, despite the ongoing technical improvements, remains quite low. It was showed that among women with smears, regarded as questionable cytological data of ASCUS, from 5% to 10%, in fact, they had severe dysplasia. The use of new molecular diagnostic methods can improve the effectiveness of screening of cervical cancer by improving the accuracy of diagnosis of the degree of dysplasia. Neoplastic transformation of the cervix epithelium is accompanied by specific changes in the profile of siRNA expression, the evaluation of which has a great diagnostic potential. In this study, the expression of 18 miRNA was analyzed. The correlation of the expression of five miRNAs (miR-375, miR-20a, miR-196b, miR145 and miR-126) with the degree of neoplasia of the cervix was established, which allowed them to be recommended for further investigation for the purpose of introduction as a diagnostic test at the stage of cytological screening.
RECONSTRUCTIVE PLASTIC SURGERY IN COMBINED TREATMENT OF PATIENTS WITH LOCALLY ADVANCED HEAD AND NECK TUMORS
Authors: Kulbakin Denis , Choynzonov Yevgeniy , Mukhamedov Marat , Garbukov Yevgeniy , Shtin Valentin , Vasilev Ruslan , Khavkin N.
Published: November 2020

From 2008 to 2016 the Department of Head and Neck Tumors of the Tomsk Cancer Research Institute performed 120 reconstructive operations. The mostly patients had locally advanced tumor process: Т3 - 49; Т4 - 41. The localization of defects needed the reconstruction: oral cavity - 26 cases; tongue - 24 cases; skin (including defects of lower lip) - 12 cases; maxilla - 14 cases; larynx and hypopharynx - 12 cases; lips - 6 cases, cheek - 11 cases, mandibulla - 5 cases. For the reconstruction we used free flaps (83%) and pedicle flaps (17%). Good functional results were achieved in the mostly cases. Full flap necrosis was noted in 12 cases (10%). Fibular flaps necrosis was noted in 8 cases (7%). Thus reconstructive surgery promoted improvement of functional outcomes and quality of life of operated patients. Reconstructive phase of radical surgical treatment contributed full social rehabilitation of patients with head and neck tumors. To reduce postoperative complications when performing reconstructive surgery careful selection of reconstructive material was needed.
СONTRIBUTION OF POLYMORPHIC VARIATION OF ТP53 AND XRCC1 GENES TO THE SUSCEPTIBILITY TO BREAST CANCER FOR WOMEN OF KYRGYZ AND BELARUSIAN NATIONALITY - A COMPARATIVE STUDY ON MULTIFACTOR DIMENSIONALITY REDUCTION METHODS
Authors: Aldasheva Nazira , Kipen Vyacheslav , Isakova Zhaynagul , Melnov Sergey , Smolyakova Raisa , Talaybekova Elnura , Makieva Kyyal , Aldashev A.
Published: November 2020

Basing on Multifactor Dimensionality Reduction method we showed that polymorphic variants p.Q399R (rs25487, XRCC1) and p.P72R (rs1042522, TP53) correlated with increased risk of breast cancer for women from the Kyrgyz Republic and the Republic of Belarus. Cohort for investigation included patients with clinically verified breast cancer: 117 women from the Kyrgyz Republic (nationality - Kyrgyz) and 169 - of the Republic of Belarus (nationality - Belarusians). Group for comparison included (healthy patients without history of cancer pathology at the time of blood sampling) 102 patients from the Kyrgyz Republic, 185 - from the Republic of Belarus. Respectively genotyping of polymorphic variants p.Q399R (rs25487, XRCC1) and p.P72R (rs1042522, TP53) was done by PCR-RFLP. Analysis of the intergenic interactions conducted with MDR 3.0.2 software. Both ethnic groups showed an increase of breast cancer risk in the presence of alleles for SNPs Gln p.Q399R (XRCC1) in the heterozygous state: for the group “Kyrgyz” - OR=2,78 (95% CI=[1,60-4,82]), p=0,001; for the group “Belarusians” - OR=1,85 (95% СІ=[1Д1-2,82], p=0,004. Carriers with combination of alleles Gln (p.Q399R, XRCC1) and Pro (p.P72R, TP53) showed statistically significance increases of breast cancer risk as for patients from the Kyrgyz Republic (OR=2,89, 95% CI=[1,33-6,31]), so as for patients from the Republic of Belarus (OR=3,01, 95% CI=[0,79-11,56]).
PRIMARY CANCER PREVENTION: INCREASE PROTEIN INTAKE?
Authors: Marasanov Sergey , Avrasina Lyubov , Gusev P. , Kovtunova A. , Maksimenko S.
Published: November 2020

In connection with the increase in the incidence of malignant tumors worldwide cancer prevention is a topical issue. Diet features along with tobacco smoking and hyperinsolation play an important role in carcinogenesis. The aim of the work is to establish the presence and size of the correlation between protein intake and lethality from cancer. It has been established that the Spearman rank correlation coefficient between protein intake and lethality from malignant tumors was equal to 0,9, which indicated a strong feedback: the less protein in the diet the higher the lethality from cancer. To optimize the primary prevention of cancer we consider it advisable to teach the population the rules of rational nutrition with an emphasis on the need for protein intake, to hold seminars on the importance of using protein of animal origin in the courses of advanced training of doctors as well as to popularize the «European diet» in the media. Rational nutrition is one of the ways to reduce morbidity and mortality from malignant tumors.
CLINICAL AND BIOLOGICAL MODEL FOR EVALUATION OF THE EFFECTIVENESS OF SYSTEMIC THERAPY FOR BREAST CANCER
Authors: Semiglazov Vladimir , Trufanova Ye. , Krzhivitskiy Pavel , Belyaev Aleksey , Kondakova Aleksandra , Yereshchenko Sergey , Zhiltsova Yelena , Mishchenko Andrey , Bashlyk Viktoriya , Kudaybergenova Asel , Klimenko Veronika , Artemeva Anna , Semiglazov Vladislav , Busko Yekaterina , Komyakhov Aleksandr , Semiglazova Tatyana , Dashyan Garik , Krivorotko Petr , Tseluyko A.
Published: November 2020

Purpose: To create a unified system of accelerated clinical trials of new drugs and regimens for breast cancer (BC).
Materials and methods: The study included 1214 patients with BC of different stages (cT1N1, cT2N1-2, cT2-3N0-2, cT2-3N0-1, cT4N0M0). According to trepan biopsy data and immunohistochemical examination (IHC) expression of ER, PR, HER2, and Ki67 was determined. The expression TUBBßIII, TOP2a, analyzes on the BRCA1/2 mutation was studied. The clinical response to neoadjuvant treatment was determined using the physical method, ultrasonography-elas-tography, mammography, contrast magnetic resonance imaging (MRI) and single-photon emission computer mammotography (SPECT-CT).
Results: The correlation index of complete responses (cCR) and total pathomorphological responses (pCR) according to MRI was 0.80, according to ultrasound - 0.61, mammography - 0.60, palpation - 0.57. The low level of amplification of the TUBßIII mRNA gene with a high level of amplification of the TOP2-a gene is a predictor of the achievement of pCR. The inclusion of a neoadjuvant treatment of triply-negative BC carboplatin in addition to paclitaxel or eribulin increases the frequency of reaching pCR (ypT0/is(yp)N0) from 20.3% to 47%.
BIOPSY OF THE SIGNALING LYMPH NODES IN GASTRIC CANCER - CURRENT STATUS OF THE PROBLEM AND PROSPECTS
Authors: Karachun Aleksey , Pelipas Yuriy , Tkachenko Oleg , Asadchaya D.
Published: November 2020

The concept of biopsy of sentinel lymph node as the first lymph node in the pathway of lymphogenous tumor spread has been actively discussed over the past decades and has already taken its rightful place in breast and melanoma surgery. The goal of this method is to exclude vain lymphadenectomy in patients without solid tumor metastases in regional lymph nodes. In the era of minimally invasive and organ-saving operations interventions it seems obvious an idea to introduce a biopsy of sentinel lymph node in surgery of early gastric cancer. Meanwhile the complexity of lymphatic system of the stomach and the presence of so-called skip metastases are factors limiting the introduction of a biopsy of sentinel lymph node in stomach cancer. This article presents a systematic analysis of biopsy technology of signaling lymph node as well as its safety and oncological adequacy. Based on literature data it seems to us that the special value of biopsy of sentinel lymph nodes in the future will be in the selection of personalized surgical tactics for stomach cancer.
CYTOREDUCTIVE SURGERY FOR OVARIAN CANCER: A REVIEW OF LITERATURE AND ANALYSIS OF THE EXPERIENCE OF THE CLINIC FOR THIRTEEN YEARS
Authors: Gorodnova Tatyana , Bondarev Nikolay , Lavrinovich Olga , Mikaya Nikolay , Ulrikh Yelena , Urmancheeva Adiliya , Imyanitov Yevgeniy , Karachun Aleksey , Belyaev Aleksey , Smirnova Olga , Sidoruk Anna , Kotiv Khristina , Petrik Sergey , Sokolenko Anna , Ivantsov Aleksandr , Guseynov Katran , Ibragimov Zaur , Meshkova Irina , Nekrasova Yekaterina , Berlev Igor
Published: November 2020

The article presents the world experience of cytoreductive surgery for ovarian cancer (OC) according to literature data and also estimates the thirteen-year experience of the Oncogynecology Department of the N.N. Petrov National Medical Research Center of Oncology in the treatment of OC patients. Materials and methods: In order to analyze the results of treatment for thirteen years it is proposed a comparative evaluation of results of primary and interval cytoreductive operations in 213 patients with OC. For this purpose all patients depending on the start of treatment were divided into two groups: a group of patients with an advanced OC where treatment started with neoadjuvant chemotherapy and a group of patients with an advanced OC where primary cytoreductive surgery was performed at the start of treatment. In these groups the long-term results of treatment were studied: platinum-free interval and life expectancy.
Results: When studying the effect of a number of neoadjuvant chemotherapy courses on long-term results of treatment it was established that the best results for platinum-free interval were obtained in a 3-course group of neoadjuvant chemotherapy - platinum-free interval was 9.6 months compared to 6.9 and 4.7 months in groups of 4 and> 5 courses although the differences in the groups did not reach statistically significant rates (p = 0.337). The increase in a number of postoperative chemotherapy courses in our study also statistically was unreliable and had a negative effect on survival: patients from the neoadjuvant chemotherapy group with> 3 courses of postoperative chemotherapy had 9.6 months versus 11.7 months in patients with 3 courses p = 0.787); life expectancy was 35.6 months compared to 30.9 months respectively (p = 0.968). The same tendency was also observed in patients from the primary cytoreduction group: in the group of patients with> 3 courses of postoperative chemotherapy platinum-free interval was 10.2 months compared to 16.3 months in patients with 3 courses (p = 0.312); life expectancy was 54.4 months compared with 48.7 months respectively (p = 0.435). The Kaplan-Meier survival estimation revealed a statistically significant improvement in life expectancy index for patients from the primary cytore-duction group (median survival time 53.7 months, 95 % CI 41.9-73.6 months) compared to patients in the neoadjuvant chemotherapy group (median life expectancy 33.0 months, 95 % CI 20.6-42.0 months, p <0.000001).
RESULTS OF TREATMENT OF LOCALLY RECURRING SOFT TISSUES SARCOMAS OF EXTREMITIES
Authors: Zinovev Grigoriy , Gafton Georgiy , Novikov Sergey , Gafton Ivan , Busko Yekaterina , Kadyrleev Roman , Grinenko I. , Elmurzaev A.
Published: November 2020

Background: The most striking clinical feature of soft tissues sarcomas (STS) is their ability to recur. At present disputes about the clinical and morphological factors of STS recurrence such as the degree of malignancy, size, location, depth of tumor location, patient’s age and the presence of previous relapses in the anamnesis do not subside. It also requires clarification of the effect of the volume of tissues removed on the long-term results of treatment of STS as well as indications for the application of various regimes of remote radiation therapy.
Materials and methods: Of 1802 registered cases of STS of extremities at the N.N. Petrov National Medical Research Center of Oncology from 2004 to 2016 there were selected data on 213 patients who suffered from at least one relapse of the disease. There was performed an assessment of overall, non-metastatic and disease-free survival using a single-factor (the Kaplan-Meier method) and multivariate analysis (the Cox regression model).
Conclusion: The detection of various prognostic factors of locally recurrent STS allows determining the necessary treatment tactics (the vastness and traumatism of surgery and the advisability of radiation therapy).
LIST OF REASONS FOR CHANGING THE SYSTEM OF STATE REPORTING OF ONCOLOGICAL SERVICE
Authors: Merabishvili V.
Published: November 2020

LIST OF REASONS FOR CHANGING THE SYSTEM OF STATE REPORTING OF ONCOLOGICAL SERVICE.
The teaching of graphical calculus in engineering schools (1860-1970)
Authors: Tournès Dominique
Published: November 2020

Graphical calculus is the part of numerical calculation that is based on geometrical constructions. It was established as a subject of knowledge and teaching from the 1860s onwards. With its three specialized components, graphical statics, graphical integration and nomography, it was a response to the growing calculation needs of engineers at the time of the industrial revolutions and the development of communication channels. It then became progressively obsolete in the 1960s due to the increasing role of computers and electronic calculators. The aim of the present contribution is to examine the content of graphical calculus courses created in engineering schools and universities between 1860 and 1960. Through a quantitative study of the treatises intended for the teaching of graphical calculus, we will also attempt to analyse, both chronologically and geographically, the diffusion processes of this teaching in Europe and the rest of the world during the period under consideration. Keywords: history of mathematics, mathematics education, mathematics of engineers, graphical calculus, graphical statics, graphical integration, nomography
PENGARUH PENGGUNAAN MEDIA PEMBELAJARAN E-LEAFLET SEBAGAI MEDIA INTERAKTIF TERHADAP MATERI HARDWARE DI SMAN 7 KUPANG
Authors: Yunus Isnai
Published: November 2020

Tujuan dalam penelitian ini untuk mengetahui pengaruh penggunaan media pembelajaran e-leaflet berbasis android sebagai media interaktif terhadap materi hardware.Berdasarkan Hasil daya beda soal kriteria jelek 3 soal, kriteria cukup 14 soal, kriteria baik 3 soal,sedangkan hasil tingkat kesukaran diperoleh 17 soal dengan kriteria mudah, dan 3 soal kriteria sedang, dan distraktor 125% atau 13 responden, baik 75% atau 14 responden, kurang baik 175% atau 6 responden.Persentase indikator kelas eksperimen post-test C1 (mengingat) sebesar 75% > kelas kontrol hanya memiliki nilai C1 (mengingat) sebesar 59% , dengan uji deskriptif kelas eksperimen post-test dengan nilai rata-rata sebesar 78 > kelas kontrol mempunyai nilai rata-rata sebesar 70, dengan uji prasyarat analisis untuk uji normalitas nilai sig. 2 tailed > 0,05 maka dapat diperoleh bahwa semua data berdistribusi normal, dengan uji linieritas nilai > sig.0,05 data keseluruhan berasal dari data yang linear,maka dengan uji homogenitas maka nilai sig. > 0,05 secara keseluruhan berasal dari data yang sama (homogen). Sedangkan Uji t independent dengan menggunakan menunjukan bahwa dilihat dari sig.(2-tailed) < α (0,05) maka H0 ditolak dan Ha diterima. Hasil angket diperoleh menunjukan nilai sebesar 120% (sangat setuju) jika media pembelajaran e-leaflet berbasis android sebagai media interaktif terhadap materi hardware dapat digunakan dalam proses pembelajaran. Disimpulkan bahwa dengan menggunakan media pembelajaran e-leaflet berbasis android dapat meningkatkan hasil belajar siswa
RIESGOS ERGONOMICOS EN MIEMBROS SUPERIORES EN UNA FABRICA DE ENVASES DE ACEITES EN MANTA-ECUADOR
Authors: MEDRANDA ZAMBRANO ROSA GENITH
Published: November 2020

Objetivos:    Evaluar los   riesgos ergonómicos   en obreros de una envasadora de aceites   por movimientos repetitivos y posturas forzadas para   determinar la relación de trastornos musculoesquelético y riesgos ergonómicos con la aplicación de método Ocra, Reba, para establecer medidas preventivas. Método:  Se desarrolló un estudio descriptivo, transversal, la muestra estuvo conformada por 9 empleados de una empresa procesadora de aceites en Manta- Manabí, se aplicó los métodos Ocra, Reba, Cuestionario Nórdico.  Resultados: Los envasadores de aceites 100% son de sexo masculinos, según estudio y con los diferentes métodos se determinó que necesita por movimientos repetitivos, posturas forzadas y manipulación manual de carga que adoptan en su jornada laboral intervencion inmediata. Conclusiones: Se determinó que los envasadores tienen una alta prevalencia a desarrollar sintomatología musculo esqueléticos en cuello, hombros, mano – muñeca – área lumbar, asociado a movimientos repetitivos posturas forzadas, manipulación de carga en la jornada laboral. Se evidencio que el personal   se encuentra expuesto   a un alto nivel de riesgos ergonómicos que afectarían en su   rendimiento, producción y vida social
MOVIMIENTOS REPETITIVOS Y TRASTORNOS MÚSCULO ESQUELÉTICOS DE MIEMBRO SUPERIOR EN TRABAJADORES CON DISCAPACIDAD INTELECTUAL
Authors: ROSERO FREIRE MARÍA CRISTINA
Published: November 2020

Objetivos: Evaluar el riesgo ergonómico por movimientos repetitivos en el personal con discapacidad intelectual de un centro de inclusión y analizar la morbilidad por trastorno músculo esquelético de miembro superior para diseñar un puesto de trabajo que permita reducir el riesgo ergonómico en miembro superior de los trabajadores.Metodología: Estudio de caso, en base a la revisión de las historias clínicas de los trece trabajadores del área, determinando la distribución de casos por sexo, edad y discapacidad, además de la tasa de prevalencia de casos por patología de miembro superior diagnosticado por clínica e imagen y la evaluación del riesgo ergonómico por el método Assessment tool for repetitive tasks of the upper limbs que es específico para personal vulnerable.Resultados: El nivel de riesgo ergonómico es alto, doce de los trece trabajadores del área tienen una afección musculo esquelética de miembro superior, encontrando los siguientes diagnósticos por ecografía: Tenosinovitis de flexores y extensores de mano 92%, tendinitis del tendón largo de la cabeza del bíceps 70% y tendinitis de supraespinoso 31%, sin que exista una relación con la edad y sexo, mostrando una asociación con las actividades del puesto de trabajo. Se realizó la mejora en el diseño de puesto de trabajo, disminuyendo el riesgo.Conclusiones: El riesgo ergonómico por movimiento repetitivo identificado en el área compromete la salud musculo esquelética de los trabajadores, es necesario que las empresas inclusivas no escatimen esfuerzos para mitigar riesgos que posiblemente no son identificados por el personal con capacidades especiales y que pueden dar lugar a la presentación de enfermedades posiblemente relacionadas a la actividad, el trabajo multidisciplinario en el centro de inclusión con el apoyo gerencial permitió que el riesgo se mitigue, mejorando el ambiente laboral percibido además por los trabajadores.
Notulae to the Italian alien vascular flora: 10
Authors: Galasso Gabriele , Domina Gianniantonio , Azzaro Dario , Bagella Simonetta , Barone Giulio , Bartolucci Fabrizio , Bianco Mattia , Bolzani Paola , Bonari Gianmaria , Boscutti Francesco , Buono Sergio , Cibei Carlo , Conti Fabio , Di Gristina Emilio , Fanfarillo Emanuele , Franzoni Jacopo , Giacanelli Valeria , Gubellini Leonardo , Hofmann Nicole , Laface Valentina L. A. , Latini Marta , Liccari Francesco , Lonati Michele , Longo Daniela , Lunesu Loredana , Lupoletti Jacopo , Magrini Sara , Mei Giacomo , Mereu Giuliano , Miconi Fabio , Musarella Carmelo M. , Nicolella Gianluca , Olivieri Nicola , Peruzzi Lorenzo , Pica Antonio , Pinzani Lorenzo , Pittarello Marco , Prosser Filippo , Ranno Veronica , Ravetto Enri Simone , Rivieccio Giovanni , Roma-Marzio Francesco , Scafidi Filippo , Spampinato Giovanni , Stinca Adriano , Tavilla Gianmarco , Tiburtini Manuel , Villa Milena , Wellstein Camilla , Zerbe Stefan , Nepi Chiara
Published: November 2020

In this contribution, new data concerning the distribution of vascular flora alien to Italy are presented. It includes new records, confirmations, exclusions, and status changes for Italy or for Italian administrative regions. Nomenclatural and distribution updates published elsewhere are provided as Suppl. material 1.
L’émergence d’un État à l’ombre d’un empire
Authors: Majid Majid A.
Published: November 2020

L’intérêt manifesté par la Grande-Bretagne à l’égard du territoire irakien remonte bien avant la première Guerre Mondiale. Sa position géographique, le croisement et la proximité de ses frontières avec la partie Sud du territoire iranien, les différentes principautés et émirats arabes situés sur la rive occidentale du Golfe, faisaient de l’Irak un objet de convoitise pour les Anglais. Ajoutons les richesses pétrolières que recèle le sous-sol de ces régions.

Déjà au XIXe siècle le « marchand anglais » est devenu un résident politique. Il revendique des avantages et même une certaine forme de protectorat non déclaré.

A cet égard, Lord Curzon indique : « Les relations entre la Grande-Bretagne et le Golfe sont passées des livres de comptes des marchands aux valises diplomatiques des hommes politiques ».

De plus, il déclare en 1911 devant le Conseil des Lords : « qu’on a tout à fait tort de croire que les intérêts politiques de la Grande- Bretagne s’arrêtent au Golfe ou à Bassorah, ils s’étendent jusqu’à Bagdad elle-même ».
Polonais méconnus
Authors: Ponty Janine
Published: November 2020

Nouvelle édition d’un ouvrage sorti initialement en 1988 et devenu au fil des années un classique sur un sujet de plus en plus en prise avec la réflexion historique et mémorielle : l’immigration.

Il ne s’agit pas de tous les Polonais en France mais de la catégorie la plus nombreuse : ceux qui, recrutés à l’appel du patronat français, reçurent le statut de » travailleurs étrangers ». Après la conclusion d’une convention franco-polonaise d’émigration en 1919, c’est par centaines de milliers que des paysans pauvres, des chômeurs et des mineurs de Westphalie acceptèrent de signer un contrat.

Cet ouvrage s’appuie sur des archives et des témoignages recueillis auprès des immigrés eux-mêmes, à présent décédés. Il cherche, d’une part à préciser les conditions du recrutement et du voyage vers la France, la vie dans les mines, l’industrie et l’agriculture avec un point d’ancrage prioritaire mais non exclusif en Nord-Pas-de-Calais. D’autre part, il analyse l’effort accompli par les intéressés pour préserver leur langue et leur culture nationales, les tentatives du gouvernement de Varsovie pour encadrer la communauté polonaise à l’étranger, les effets dramatiques de la grande crise économique, la courte embellie du Front populaire assortie d’une soudaine syndicalisation, puis le repli sur soi à la veille de la guerre de la part d’ouvriers dont l’intégration aux valeurs françaises n’est encore qu’à peine amorcée à cette date.
Identification of climatic and environmental factors associated with incidence of cutaneous leishmaniasis in Central Iran using satellite imagery
Authors: Javanbakht Mohammad , Saghafipour Abedin , Ezimand Keyvan , Hamta Amir , Zanjirani Farahani Leyli , Soltani Nazanin
Published: November 2020

Objective:

To determine the effect of climatic and environmental factors on the incidence of cutaneous leishmaniasis in Qom province in 2018.

Methods:

In this cross-sectional study, the data on cutaneous leishmaniasis incidence were collected from the Disease Control and Prevention Center in Qom province. Climatic and environmental data including Normalized Difference Vegetation Index (NDVI), Land Surface Temperature (LST), and soil moisture were extracted using satellite images. Data of altitude and sunny hours were provided based on shuttle radar topography mission digital elevation model and hemispherical viewshed algorithm, respectively. The associations of climatic and environmental variables with the incidence of the disease were analyzed by Pearson correlation method. The ArcGIS 10.3 software was used to determine the geographical distribution of these factors.

Results:

There were positive correlations between cutaneous leishmaniasis incidence and the two climatic factors: LST and sunny hours per day (P=0.041, P=0.016), and it had weak negative correlations with the digital elevation model (P=0.27), soil moisture (P=0.54), and NDVI (P=0.62). The time delay analysis showed that in one-, two-, and three month periods, the correlations increased with a 95% confidence interval. Accordingly, the correlation with the three-month time delay was positive and relatively strong between the cutaneous leishmaniasis incidence and LST and sunny hours (P=0.027, P=0.02); nevertheless, there were negative correlations between the cutaneous leishmaniasis incidence and the soil moisture (P=0.27) and NDVI (P=0.62).

Conclusions:

As Qom is located in one of the semi-arid climate zones, topography and solar energy are important factors affecting the incidence of cutaneous leishmaniasis in autumn. Therefore, appropriate disease control programs are recommended.
Risk factors for penile fracture compared with a surgical control cohort in the United States
Authors: Christian-Miller Nathaniel , Lenis Andrew T , Fero Katherine E , Madrigral Josef , Eleswarapu Sriram V , Chamie Karim , Benharash Peyman
Published: November 2020

Penile fracture (PF) is a surgical emergency. Given its rarity, we queried a national cohort over an 11-year period to study the temporal and demographic variations in presentation, evaluation, and management of patients with PF compared with a cohort of control patients. The National Inpatient Sample was queried between the years 2005 and 2016 for patients with a diagnosis of PF. Appendectomy patients were selected as a control cohort, given the non-discriminatory nature of this disease. Clinical and demographic data of the patients were compared with that of controls. Presenting symptoms, rates of surgical repair, and rates of associated surgical procedures were evaluated in the PF cohort. During the study period, 5802 patients were hospitalized for PF. The annual incidence of PF remained unchanged at 1.0–1.8 cases per 100 000 hospitalizations over the study period. Compared with the control cohort, PF patients were more likely to be younger (38.7 years vs 41.2 years, P ≤ 0.001), have lower rates of comorbidities except erectile dysfunction (1.4% vs 0.1%, P ≤ 0.001), and were more likely of Black race (25.4% vs 6.2%, P ≤ 0.001). Notably, PF patients had significantly higher rates of substance abuse (26.4% vs 18.1%, P ≤ 0.001), despite no difference in the diagnosed psychiatric disorders. PF rarely presented with hematuria (3.5%); however, urethral evaluation was performed in 23.1%, most commonly with cystoscopy (19.2%). PF occurs more commonly in a younger, healthier male population, and among minorities. Importantly, rates of substance abuse appear to be higher in the PF cohort compared with those of controls.
Achieving international species conservation targets
Authors: Maira Louise , Byers Onnie , Lees Caroline M. , Nguyend Dao , Rodrigueze Jon Paul , Smart Jane , McGowan Philip J. K.
Published: November 2020

In 2010, the Convention on Biological Diversity (CBD) outlined an international strategic plan, which included the twenty Aichi Biodiversity Targets to be met by 2020. Target 12 refers to preventing extinctions and halting species declines. Despite some local conservation successes, this target is not on track to be met at the global level. We aimed to understand what is needed to achieve this target according to two invested but contrasting groups: species conservation experts and global conservation policy makers. We surveyed a diversity of species conservation experts and contrasted their views with those of policy makers engaged with CBD. Species experts considered that the greatest need was for increased political will, while policy makers most frequently cited the need for increased knowledge of species conservation status. Both groups did, however, emphasise that achieving species conservation targets requires greater progress to be made towards many of the other Aichi Targets. We suggest that improved communication, collaboration and data sharing among institutions should be a priority to help overcome the perceived knowledge-gap. Doing so could help to align the views of practitioners and policy makers, and develop a shared understanding of the key actions needed to accelerate progress towards global biodiversity targets.
Sistema de gestión de inocuidad alimentaria y la calidad en empresas pesqueras
Authors: Soledispa-Lucas Fausto Freddy
Published: November 2020

Una economía que basa su desarrollo en el sector pesquero industrial tiene en las unidades empresariales dedicadas al procesamiento y conservas de atún en el eje principal y aglutinador de las actividades productivas. Se constituye en un encadenamiento que genera valor agregado, se propicia empleo de mano de obra calificada y no calificada, orientando hacia una dinámica que se inserta de manera favorable hacia la matriz productiva con enlaces adecuados hacia una matriz energética, denotando eficacia en el manejo de costos de producción. La producción y riqueza generada impulsan el logro de una economía de bienestar, convirtiéndose en la base del crecimiento económico y desarrollo de la región y el país. La investigación tiene como objetivo principal medir como la calidad tiene un impacto en la competitividad del sector industrial de las empresas enlatadoras de atún en la ciudad de Manta. En tal virtud, la aplicación de la norma de inocuidad alimentaria, constituyen una base crítica para garantizar el cumplimiento de estándares de calidad, como mejora continua en los procesos productivos de la empresa. El estudio analiza otras características con la finalidad de identificar elementos que crean la competitividad de las organizaciones industriales en los mercados. El estudio desarrolló la prueba estadística de Cronbach, obteniendo un alfa de 0,947, que confiere un grado de fidelidad en los datos recogidos. Los resultados estadísticos revelan que la calidad influye en la competitividad de las empresas del sector industrial pesquero. Palabras claves: Calidad; competitividad; inocuidad alimentaria, enlatados de atún, industria.
EL COVID-19 Y SU INCIDENCIA EN LA SALUD MENTAL DE LOS MORADORES DE LA CIUDADELA EL FLORÓN # 5 DEL CANTÓN PORTOVIEJO
Authors: Pinargote-Macías Eleticia Isabel , Moreira-Vera Fátima Sabrina
Published: November 2020

El Covid-19, considerado como una emergencia de salud pública a nivel planetario por los estragos que genera en la población, es sin duda hoy, un factor inmanente al deterioro de la salud mental. El presente artículo tiene como objetivo determinar la incidencia del Covid-19 en la salud mental de los moradores de la Ciudadela el Florón # 5 del cantón Portoviejo. La metodología corresponde a un diseño de campo de tipo descriptivo de corte transversal, apoyada en el método deductivo – inductivo. Los datos obtenidos a través del análisis de las categorías consideradas en el test SF-36 son de naturaleza cuantitativa. Para el estudio, se tomó una muestra representativa de 274 habitantes en edades comprendidas entre 20 y 49 años quienes fueron seleccionados mediante muestreo no probabilístico bola de nieve y respondieron el cuestionario a través de la plataforma google form. Entre los resultados más relevantes se destacan las limitaciones en la salud para el desarrollo de las actividades normales, presencia de molestias físicas y problemas emocionales. Estos datos fueron contrastados con otras investigaciones en este campo, los mismos que permitieron determinar que el Covid- 19 ha provocado en la población objeto de estudio, problemas de carácter físico y emocional, lo que ha perjudicado sus relaciones en el contexto familiar y social, así como también el estado de la salud mental. Palabras clave: Covid-19, coronavirus, pandemia, salud mental, Portoviejo.