bluuebunny/crossref_metadata_2025 huggingface dataset:
The current epizootic and epidemiological situation of coxiellosis in the territories of the Southern, North Caucasian Federal Districts, Donetsk, Lugansk People's Republics, Zaporizhia and Kherson regions
Authors: Sokirkina E. N. , Noskov A. K. , Pichurina N. L. , Tsay A. V. , Simakova D. I. , Kovalev Ye. V.
Published: June 2024

Objective: to characterize the dynamics and intensity of the incidence of Q fever for the period from 2015 to 2022, to determine the risk areas for human infection in the Southern and North Caucasian Federal districts and in the new subjects of the Russian Federation.

Materials and methods: for epidemiological analysis, materials from analytical reviews "The epidemiological situation of natural focal infectious diseases in the Southern and North Caucasus Federal Districts" and state reports "On the state of sanitary and epidemiological welfare of the population" for 2015-2022, reporting data from the Rospotrebnadzor Department for the Rostov region, «Center for Hygiene and Epidemiology in Russia Rostov region» and the Departments of Rospotrebnadzor for the DPR and LPR. From 2022–2023 PCR study was conducted for the presence of Coxiella burnetii DNA in samples of ixodic mites and small mammals in the Rostov region and in 2023 – in the DPR, LPR, Zaporizhia and Kherson regions.

Results: the analysis of the territorial distribution of cases of Q fever in the Astrakhan region and Stavropol Territory revealed a cluster of the most disadvantaged areas. An analysis of the conditions of infection of patients with Ku fever in the Rostov region has established that the most likely transmission factors are environmental objects in private farms. The circulation of C. burnetii in natural biotopes of the Rostov region, DNR and LNR regions.

Conclusions: the epidemic process of Ku fever is mainly local, limited in the context of municipal districts of Astrakhan and Rostov regions, Stavropol Territory. The sporadic incidence of Ku fever does not reflect its actual level. There is no convincing evidence indicating the leading role of farm animals as a primary link in the formation of the epizootic process of Q fever in anthropurgical foci.
Working condition and health status of employees of the aviation enterprise
Authors: Sabitova M. M. , Shulaev A. V. , Berkheeva Z. M. , Garipova R. V. , Sabitov A. Z.
Published: June 2024

Objective: a hygienic assessment of working conditions and an analysis of the morbidity of aircraft workers.

Materials and methods: the study was carried out on the basis of data from the Office of the Federal Service for Supervision of Consumer Rights Protection and Human Well-Being in the Republic of Tatarstan (Tatarstan) and the Center for Occupational Pathology Scientific and Clinical Center for Preventive Medicine of the Institute of Fundamental Medicine and Biology of the Kazan (Volga Region) Federal University.

Results: hygienic monitoring of the working conditions of employees of the aviation plant showed a combined effect of harmful factors of the production environment and the labor process, corresponding to classes 3.1–3.2 in a number of professions. Among the diseases identified in employees of the enterprise, diseases of the eye and its accessory apparatus, circulatory organs and hearing predominate. According to the results of the medical examination, 6.4% of the subjects were found to have a suspicion of occupational chronic bilateral sensorineural hearing loss.

Conclusions: research results indicate that there is a risk of developing occupational pathology as a result of exposure to physical factors. The employer was given recommendations to improve working conditions and preserve the health of workers.
Comparative effectiveness of different methods of prescribing rosuvastatin and ezetimibe in combination with PCSK9 inhibitors
Authors: Kuznetsov A. A. , Mal G. S. , Saraev I. A.
Published: June 2024

Objective: comparative evaluation of the effectiveness of combined lipid-lowering therapy with rosuvastatin and ezetimibe in fixed and separate combinations with PCSK9 inhibitors in patients with very high cardiovascular risk.

Materials and methods: 65 study participants were divided into 2 groups depending on the method of combined lipid-lowering therapy and were observed for 5 months on 6 visits. The effectiveness of the hypolipidemic response in each of the studied groups was evaluated.

Results: in the group with separate administration of lipid-lowering drugs, the target values of LDL cholesterol reached 50% of patients, the level of LDL cholesterol during 5 months of treatment decreased by 38.22% from 2.25 [1.82; 2.47] mmol/l to 1.39 [1.21; 1.59] mmol/l (p <0.001). In the group with a fixed combination of rosuvastatin and ezetimibe, 61.29% of the study participants reached the target ranges of LDL cholesterol, the concentration of LDL cholesterol decreased by 47.46% from 2.36 [1.92; 2.57] mmol/l to 1.24 [1.18; 1.56] mmol/l (p <0.001). Logistic regression analysis showed a significant association of females with a higher risk of not reaching the target ranges of LDL cholesterol (χ2<0.001; OR 0.13 95 % CI 0.04-0.39; p<0.001).

Conclusion: the use of a fixed combination of rosuvastatin and ezetimibe in combination with PCSK9 inhibitors in patients with very high cardiovascular risk makes it possible to reduce the concentration of LDL cholesterol by 9.24% more intensively relative to the drug regimen with separate administration of drugs.
Web-Based Forums for People Experiencing Substance Use or Gambling Disorders: Scoping Review
Authors: Peart Annette , Horn Freya , Petukhova Rachel , Barnett Anthony , Lubman Dan I
Published: June 2024

Background

For people experiencing substance use or gambling disorders, web-based peer-supported forums are a space where they can share their experiences, gather around a collective goal, and find mutual support. Web-based peer support can help to overcome barriers to attending face-to-face meetings by enabling people experiencing addiction to seek support beyond their physical location and with the benefit of anonymity if desired. Understanding who participates in web-based peer-supported forums (and how), and the principles underpinning forums, can also assist those interested in designing or implementing similar platforms.

Objective

This study aims to review the literature on how people experiencing substance use or gambling disorders, and their family, friends, and supporters, use and participate in web-based peer-supported forums. Specifically, we asked the following research questions: (1) What are the characteristics of people who use web-based peer-supported substance use or gambling-focused forums? (2) How do people participate in web-based peer-supported forums? (3) What are the key principles reportedly underpinning the web-based peer-supported forums? (4) What are the reported outcomes of web-based peer-supported forums?

Methods

Inclusion criteria for our scoping review were peer-reviewed primary studies reporting on web-based addiction forums for adults and available in English. A primary search of 10 databases occurred in June 2021, with 2 subsequent citation searches of included studies in September 2022 and February 2024.

Results

Of the 14 included studies, the majority of web-based peer-supported forums reported were aimed specifically for, or largely used by, people experiencing alcohol problems. Results from the 9 studies that did report demographic data suggest forum users were typically women, aged between 40 years and early 50 years. Participation in web-based peer-supported forums was reported quantitatively and qualitatively. The forums reportedly were underpinned by a range of key principles, mostly mutual help approaches and recovery identity formation. Only 3 included studies reported on outcomes for forum users.

Conclusions

Web-based peer-supported forums are used by people experiencing addiction in a number of ways, to share information and experiences, and give and receive support. Seeking web-based support offers an alternative approach to traditional face-to-face support options, and may reduce some barriers to engaging in peer support.
A Prediction Model for Identifying Seasonal Influenza Vaccination Uptake Among Children in Wuxi, China: Prospective Observational Study
Authors: Wang Qiang , Yang Liuqing , Xiu Shixin , Shen Yuan , Jin Hui , Lin Leesa
Published: June 2024

Background

Predicting vaccination behaviors accurately could provide insights for health care professionals to develop targeted interventions.

Objective

The aim of this study was to develop predictive models for influenza vaccination behavior among children in China.

Methods

We obtained data from a prospective observational study in Wuxi, eastern China. The predicted outcome was individual-level vaccine uptake and covariates included sociodemographics of the child and parent, parental vaccine hesitancy, perceptions of convenience to the clinic, satisfaction with clinic services, and willingness to vaccinate. Bayesian networks, logistic regression, least absolute shrinkage and selection operator (LASSO) regression, support vector machine (SVM), naive Bayes (NB), random forest (RF), and decision tree classifiers were used to construct prediction models. Various performance metrics, including area under the receiver operating characteristic curve (AUC), were used to evaluate the predictive performance of the different models. Receiver operating characteristic curves and calibration plots were used to assess model performance.

Results

A total of 2383 participants were included in the study; 83.2% of these children (n=1982) were <5 years old and 6.6% (n=158) had previously received an influenza vaccine. More than half (1356/2383, 56.9%) the parents indicated a willingness to vaccinate their child against influenza. Among the 2383 children, 26.3% (n=627) received influenza vaccination during the 2020-2021 season. Within the training set, the RF model showed the best performance across all metrics. In the validation set, the logistic regression model and NB model had the highest AUC values; the SVM model had the highest precision; the NB model had the highest recall; and the logistic regression model had the highest accuracy, F1 score, and Cohen κ value. The LASSO and logistic regression models were well-calibrated.

Conclusions

The developed prediction model can be used to quantify the uptake of seasonal influenza vaccination for children in China. The stepwise logistic regression model may be better suited for prediction purposes.
Novel Profiles of Family Media Use: Latent Profile Analysis (Preprint)
Authors: Hamp Nicole , Radesky Jenny , Weeks Heidi M , Miller Alison L , Kaciroti Niko
Published: June 2024

BACKGROUND

Over the past three decades, digital and screen media have evolved from broadcast, stationary platforms to a complex environment of interactive, omnipresent, mobile media. Thus, clinical guidance centered around unidimensional concepts such as ‘screen time’ must be modernized to help families navigate the intricate digital ecosystems of readily available entertainment and information.

OBJECTIVE

This study aimed to identify and examine distinct latent profiles of media use in families with young children. We hypothesized that latent profile analysis (LPA) would identify different media use profiles characterized by more heavy, reactive, individual, and permissive media use; and more intentional, regulated, and/or shared uses of media.

METHODS

We analyzed data from 398 preschool-aged children. English-speaking parents were recruited through community settings. Participants completed surveys regarding several aspects of family media use: child device use/activities; parent concerns/attitudes; limit setting and mediation; parent media use; and technology interference; these were examined in a latent profile analysis (LPA). The number of latent media profiles was determined using Bayesian Information Criteria. Parents also completed validated scales of parenting stress, depression symptoms, parenting style, child behavior, child sleep, and household disorganization. Multivariable logistic regression was used to examine parent, child, and household predictors of group membership.

RESULTS

The LPA yielded 2 distinct groups that differed in the duration of media used by parents and children, use to calm children, or help children fall asleep. Statistically significant differences between groups included: families in Group 1 (n=236, which we termed Media as Social-Emotional Buffer) had parents who preferred interactions via text or email to in-person (p=0.006) and were more likely to use media to calm their children (p=0.03). In contrast, Group 2 (n=162, Intentional Media) used more task-oriented media, including audio and non-game apps (p=0.01), had more concerns about effects of media on child language development (p=0.04), and used more media restrictions (p=0.01). In regression models, female sex of the parent respondent, greater number of siblings, and later child sleep period independently predicted Group 1 membership.

CONCLUSIONS

Findings suggest divergent family media use patterns that can be categorized into two main media user groups – those that use media to buffer social situations or regulate emotions and those that plan mobile device use around functional purposes and concerns around media exposure. Profiles associate with household size and child sleep. More research is needed to examine the impact of social and emotional uses of media on child outcomes.

CLINICALTRIAL

NICHD R21HD094051
Poet-Composer Collaborations in Modern Egyptian Song: A Social Network Analysis Approach to Music History
Authors: Frishkopf Michael
Published: June 2024

In this paper I formulate and apply a social network analysis methodology for understanding the history of song on Egyptian radio. Music is a massively relational cultural form, involving interactions among composers, poets, arrangers, conductors, and performers, among others. The reality of music history thus emerges as a complex network of relationships, unfolding and changing over time. Song production, in particular, centers on poet-composer-singer collaborations. Many Arab music histories highlight narratives of the stars, presented in historical and cultural context, but neglect the broader network of productive relationships. However many important musical figures are not celebrities, and the full complexity of the non-linear network can only be grasped holistically, including big data empirical analysis, not pointillistically through case studies of celebrities. Such holistic analysis can reveal surprising emergent, structural patterns that are not apparent in any single narrative. Social network analysis (SNA) offers a powerful suite of tools enabling such an approach, including metrics for centrality and the detection of cohesive subgroups. Starting with a large dataset of songs broadcast on Egyptian radio, I extract a network of poet-composer collaborations, and apply SNA algorithms to reveal its social structure. I then interpret that structure in light of wider socio-cultural and historical factors. In this way, my paper both sheds light on Egypt’s musical history, and supplies a model and method that may be applied, mutatis mutandis, to other musical domains.
Algorithm-Based Recommendations: A Study on the Media Behavior of "Lurking" Participants
Authors: Zhang Yunjun , Xiao Beini
Published: June 2024

This study delves into the media behaviors of "lurking" participants, a distinct user group, by analyzing their activities in the online space. It uncovers the multifaceted impacts of algorithmic recommender systems on "lurking" participants. The research finds that algorithms not only profoundly influence users' content selection and preference development but also play a pivotal role in shaping their social interaction patterns, thereby having profound effects on the overall information ecosystem. Furthermore, this study explores the complexities of how algorithmic recommender systems mold users' information consumption habits.
Dog’s Breed Prediction using Deep Learning
Authors: Jagadesh K.
Published: June 2024

Abstract: Dog Breed Prediction from Images using Deep Learning, in this project, we propose a Convolutional Neural Network (CNN) based approach for predicting dog breeds from images. With the increasing popularity of dogs as pets and the need for proper care and maintenance, it is essential to identify the breed of a dog accurately. However, manual identification can be time-consuming and prone to errors. Therefore, we propose a deep learning-based solution that can predict the breed of a dog with high accuracy. We train a CNN model on a large dataset of dog images, where each image is labeled with the breed of the dog. The model learns to extract features from the images and classify them into one of the 180 breeds. We evaluate the performance of the model using standard metrics and compare it with other machine learning algorithms. Our experimental results show that the proposed CNN model outperforms other algorithms in predicting dog breeds from images. The model achieves an accuracy of 90%, making it a reliable tool for dog breed prediction. Additionally, we develop a web application that allows users to upload an image of a dog and predict its breed using our model. This project demonstrates the effectiveness of deep learning techniques in predicting dog breeds from images. The proposed CNN model can be a valuable tool for veterinarians, pet owners, and breeders, helping them identify the breed of a dog accurately and efficiently.
Principal Support for Teacher Vitality: An Empirical Analysis in Low-Performing Schools
Authors: Adams Curt , Hamlin Daniel , Adigun Olajumoke
Published: June 2024

This article draws on a teacher survey (n = 789) to examine the relationship between teacher vitality and two conversational approaches—transformative leadership conversation and controlling conversation. The analyses use latent structural equation modelling. The sample is restricted to teachers in schools with an accountability rating of “low performing” so that principal/teacher conversations can be examined in schools that potentially have the most to gain from strong teacher vitality. Results indicate that the use of transformative leadership conversation had a direct positive relationship with teacher vitality (β = .26) and an indirect relationship (β = .22) with it through teacher need satisfaction. Controlling conversation had a negative relationship with teacher vitality, but it did not have a statistically significant relationship with need satisfaction.
TRABALHO DECENTE COMO PRESSUPOSTO FUNDAMENTAL DE FELICIDADE NO TRABALHO
Authors: Nunes Cleria , Silva Narbal
Published: June 2024

Objetivo: O conceito de Trabalho Decente foi criado pela Organização Internacional do Trabalho e ratificado pela Organização das Nações Unidas na Agenda 2030 ao prever atributos para o trabalho, tornando-o universalmente aceito e desejável. No mesmo sentido, ter uma vida revestida de bem-estar psicológico e subjetivo, de forma estável e perene, atende à busca humana pela felicidade. Compreender como trabalhadores de uma mesma organização percebem Trabalho Decente e Felicidade no Trabalho é o objetivo do presente estudo.
Método/abordagem: Na fase anterior da pesquisa foi aplicado o Questionário de Trabalho Decente e o Inventário Brasileiro de Felicidade no Trabalho em uma amostra de 387 trabalhadores de uma organização pública brasileira, subdivididos entre estatutários e terceirizados. Na presente etapa, de caráter qualitativo, realizou-se 20 entrevistas semiestruturadas com os respondentes que se voluntariaram para esta fase final da pesquisa.
Principais Resultados: Das três dimensões de Felicidade no Trabalho a mais importante para os trabalhadores foi novamente a Psicossocial, por meio do respeito, justiça e apoio organizacional. Os estatutários ressaltaram que o teletrabalho trouxe maior flexibilidade e oportunidades de desenvolvimento (Transcendental). Os terceirizados destacaram a expectativa de aposentadoria e proteção em caso de doença (Material de Existência).
Contribuições teóricas/práticas/sociais: O estudo valida as dimensões de ambos os construtos psicológicos como indicadores organizacionais e de qualidade de vida no trabalho.
Originalidade/relevância: Trabalho Decente é relacionado a comportamentos organizacionais positivos, como engajamento, autonomia, motivação, entre outros. Porém, este é o primeiro estudo que relaciona Trabalho Decente à Felicidade no Trabalho, conceito-chave para o movimento da Psicologia Positiva.
Campesinato e neoextrativismo em São Paulo: dinâmicas e conflitos da atividade sucroenergética na região de Ribeirão Preto
Authors: Corrêa Victor Marchesin , Carvalho Joelson Gonçalves de
Published: June 2024

Esta pesquisa investigou a dinâmica produtiva do agronegócio canavieiro e seus efeitos na reprodução social de grupos camponeses na Região Administrativa de Ribeirão Preto, interior do estado de São Paulo, importante território hegemonizado pela cana-de-açúcar e palco de diversos conflitos agrários do estado. Para tanto, foram realizadas entrevistas semiestruturadas com agentes representativos para o tema em questão, além de visitas de campo e análise de dados secundários. A partir de um paradigma histórico-dialético, o objetivo deste artigo é demonstrar que, na região em questão, se localiza uma intensiva e predatória atividade neoextrativista protagonizada pelo setor sucroenergético que, em sua lógica de produção, desorganiza e dificulta a produção e reprodução social camponesa. As conclusões indicam que, ainda que fora de zonas de fronteira, há severos impactos sobre grupos camponeses locais, resultando em despossessões, concentração fundiária e conflitos de diversas ordens.
Sample-optimal classical shadows for pure states
Authors: Grier Daniel , Pashayan Hakop , Schaeffer Luke
Published: June 2024

We consider the classical shadows task for pure states in the setting of both joint and independent measurements. The task is to measure few copies of an unknown pure state ρ in order to learn a classical description which suffices to later estimate expectation values of observables. Specifically, the goal is to approximate Tr(Oρ) for any Hermitian observable O to within additive error ϵ provided Tr(O2)≤B and ‖O‖=1. Our main result applies to the joint measurement setting, where we show Θ~(Bϵ−1+ϵ−2) samples of ρ are necessary and sufficient to succeed with high probability. The upper bound is a quadratic improvement on the previous best sample complexity known for this problem. For the lower bound, we see that the bottleneck is not how fast we can learn the state but rather how much any classical description of ρ can be compressed for observable estimation. In the independent measurement setting, we show that O(Bdϵ−1+ϵ−2) samples suffice. Notably, this implies that the random Clifford measurements algorithm of Huang, Kueng, and Preskill, which is sample-optimal for mixed states, is not optimal for pure states. Interestingly, our result also uses the same random Clifford measurements but employs a different estimator.
Variational Quantum Algorithms for Semidefinite Programming
Authors: Patel Dhrumil , Coles Patrick J. , Wilde Mark M.
Published: June 2024

A semidefinite program (SDP) is a particular kind of convex optimization problem with applications in operations research, combinatorial optimization, quantum information science, and beyond. In this work, we propose variational quantum algorithms for approximately solving SDPs. For one class of SDPs, we provide a rigorous analysis of their convergence to approximate locally optimal solutions, under the assumption that they are weakly constrained (i.e., N≫M, where N is the dimension of the input matrices and M is the number of constraints). We also provide algorithms for a more general class of SDPs that requires fewer assumptions. Finally, we numerically simulate our quantum algorithms for applications such as MaxCut, and the results of these simulations provide evidence that convergence still occurs in noisy settings.
Improving social welfare in non-cooperative games with different types of quantum resources
Authors: Abbott Alastair A. , Mhalla Mehdi , Pocreau Pierre
Published: June 2024

We investigate what quantum advantages can be obtained in multipartite non-cooperative games by studying how different types of quantum resources can lead to new Nash equilibria and improve social welfare — a measure of the quality of an equilibrium. Two different quantum settings are analysed: a first, in which players are given direct access to an entangled quantum state, and a second, which we introduce here, in which they are only given classical advice obtained from quantum devices. For a given game G, these two settings give rise to different equilibria characterised by the sets of equilibrium correlations Qcorr(G) and Q(G), respectively. We show that Q(G)⊆Qcorr(G), and by exploiting the self-testing property of some correlations, that the inclusion is strict for some games G. We make use of SDP optimisation techniques to study how these quantum resources can improve social welfare, obtaining upper and lower bounds on the social welfare reachable in each setting. We investigate, for several games involving conflicting interests, how the social welfare depends on the bias of the game and improve upon a separation that was previously obtained using pseudo-telepathic solutions.
Literatura, ensino e surdez
Authors: Cardoso Junior Waldemar dos Santos , Alves Cristiane de Mesquita
Published: June 2024

O livro Literatura, ensino e Surdez reúne os resultados de pesquisas relacionadas aos estudos sobre o ensino da Língua Brasileira de Sinais e em torno da Literatura surda e para surdos, apresentadas no formato de Comunicações orais, mais especificamente no Grupo de Trabalho 08 (Literatura- ensino e surdez) no decorrer do I Simpósio Internacional Mulheres, Gênero e Identidades Plurais na Literatura e nas Artes Amazônicas e Latino-americanas, realizado nos dias 04 a 06 de maio de 2022. O simpósio foi organizado pelo Grupo de Pesquisa Mulheres Amazônidas e Latino-americanas na Literatura e nas Artes (MALALAS/UFPA/CNPq). Ressalta-se que este livro corresponde a uma terceira publicação do Simpósio. A primeira foi o Livro dos resumos do I Simpósio Internacional Mulheres, Gênero e Identidades Plurais na Literatura e nas Artes Amazônicas e Latino-americanas e a segunda publicação: Pesquisas sobre mulheres, gênero e identidades plurais na Literatura e nas Artes (com organização dos Professores: Cristiane de Mesquita Alves, Waldemar dos Santos Cardoso Junior e Joyce Cristina Farias de Amorim e pelos alunos da Graduação da UFPA: Clayse Roque dos Santos, Giselle Cardoso da Silva e Rodrigo Thales da Rosa Ribeiro, ambos publicados pela Editora FI).
Flaubert in Dostoevsky’s Work: The Role and Image of Madame Bovary in the Novel The Idiot
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Magaril-Il’iaeva Tatiana G.
Published: June 2024

The article examines the role of G. Flaubert’s novel Madame Bovary in the artistic space of F.M. Dostoevsky’s Idiot and the philosophical and ideological ideas of the French writer, which formed the basis of his work. The research demonstrates that for Flaubert, the image of a woman captured by her fantasies and passions was a symbol of the spiritual state of his modern society, which, according to the writer, had lost its spiritual guidelines and was completely focused on itself and the satisfaction of momentary desires, while the true needs remained unsatisfied. The article shows that for the correct interpretation of the role of Madame Bovary, it is necessary to correctly take into account the time of her reading by the heroine of Dostoevsky since she did not read it before her wedding, as is commonly believed in research literature, but at the time of her departure from Pavlovsk, when she “forever” left the prince for the sake of his happiness with Aglaya. Thus, the article suggests that the image of Emma and the world that she symbolizes is primarily associated with the young Epanchina, and not with Nastasia Filippovna. The article also analyzes the death scenes of the two female characters.
The Link Between β-catenin/Wnt Signaling Pathway and Cognitive Function in Chronic Kidney Disease
Authors: Lu Liangxiang , Feng Jialun , Tang Wenzhuang , Zhu Meijuan , Zhao Cui , Wang Ziqiang , Chen Juan
Published: June 2024

Chronic Kidney Disease (CKD), which is marked by impaired kidney
function, is recognized as a significant public health issue, and
individuals with this condition are at a heightened risk of experiencing
cognitive problems simultaneously. This research evaluated the
functional importance of the β-catenin signaling pathway in cognitive
function in mice with chronic renal disease caused by adenine. The study
also aimed to determine the relevance of the influence of the β-catenin
signaling system on cognitive function and its underlying processes.
Firstly, a mouse model of CKD was created. Subsequently, the cognitive
capacity of mice with CKD was assessed using a water maze. Following
that, immunofluorescence labeling and protein blot analysis were used to
quantify the levels of β-catenin and Dickkopf-related protein -1 (DKK1)
expression in the brain and kidney of mice with CKD. This study aims to
investigate the role of β-catenin in cognitive impairment in CKD mice.
CKD mice exhibited neuronal injury and cognitive impairment, which
correlated with a significant decrease in the number of nuclei in the
frontal lobe. These nuclei had pale staining, blurred boundaries, a hazy
appearance, and, in some cases, swelling or disintegration. Furthermore,
it was proven that DKK1 exacerbates cognitive impairment in mice with
CKD by blocking the β-catenin/Wnt signaling pathway. To summarize, the
study revealed that the β-catenin signaling pathway impacts cognitive
function in mice with CKD induced by adenine. Additionally, it was
observed that increased levels of DKK1 resulted in neuronal damage in
the brain tissue of mice with CKD.
EMM EMUS Observations of FUV Aurora on Mars: Dependence on Magnetic Topology, Local Time, and Season
Authors: Chirakkil Krishnaprasad , Lillis Robert James , Deighan Justin , Chaffin Michael Scott , Jain Sonal , Brain David Andrew , Fillingim Matthew O. , Susarla Raghuram , Holsclaw Gregory , Fang Xiaohua , Schneider Nicholas M. , Almazmi Hoor , Almatroushi Hessa , Gacesa Marko , El-Kork Nayla , Thiemann Ed , Halekas Jasper S.
Published: June 2024

We present a comprehensive study of the nightside aurora phenomenon on
Mars, utilizing observations from EMUS onboard EMM. The oxygen emission
at 130.4 nm is by far the brightest FUV auroral emission line observed
at Mars. Our statistical analysis reveals geographic, solar zenith
angle, local time, and seasonal dependencies of auroral occurrence.
Higher occurrence of aurora is observed in regions of open magnetic
topology, where crustal magnetic fields are either very weak or both
strong and vertical. Aurora occurs more frequently closer to the
terminator and is more likely on the dusk side than on the dawn side of
the night hemisphere. A pronounced auroral feature appears close to
midnight local times in the southern hemisphere, consistent with the
spot of energetic electron fluxes previously identified in the MGS data.
This auroral spot is more frequent after midnight than before.
Additionally, some regions on Mars are “aurora voids” where
essentially no aurora occurs. Aurora exhibits a seasonal dependence,
with a major enhancement near perihelion. Non-crustal field aurora
additionally shows a secondary enhancement near Ls 30°. This seasonal
variability is a combination of the variability in ionospheric
photoelectrons and thermospheric atomic oxygen abundance. Auroral
occurrence also shows an increase with the rise of Solar Cycle 25. The
brightest auroral pixels are observed during space weather events such
as CMEs and SIRs. These observations not only shed light on where and
when Martian aurora occurs, but also add to our understanding of Mars’
magnetic environment and its interaction with the heliosphere.
Herramientas y metodologías para procesos de enseñanza y aprendizaje que implementan tecnologías
Authors:   Investigador Independiente, Pico Quijije Miguel Ángel , López Pinargote Jhonny Antonio ,   Investigador Independiente, Navarrete Zambrano Eduar Enrique ,   Investigador Independiente, Bucheli López Carlos Vinicio ,   Investigador Independiente, Chávez Toala Aldo Rafael ,   Investigador Independiente
Published: June 2024

En el mundo actual que avanza rápidamente, la integración de la tecnología en la educación se ha convertido en un aspecto crucial de los procesos modernos de enseñanza y aprendizaje. Las herramientas y metodologías para procesos de enseñanza y aprendizaje que implementan tecnologías desempeñan un papel importante en la configuración del panorama educativo al proporcionar formas innovadoras de involucrar a los estudiantes, mejorar los resultados del aprendizaje y prepararlos para una sociedad cada vez más digital. En tal sentido, la presente investigación tuvo como objetivo describir la importancia de las diversas herramientas, plataformas y recursos digitales para facilitar la instrucción, mejorar la participación de los estudiantes, promover la colaboración y mejorar las experiencias de aprendizaje en general. Por consiguiente, se resalta entre los resultados que la integración de la tecnología en la educación, permite crear entornos de aprendizaje dinámicos que satisfagan las diversas necesidades de los estudiantes y al mismo tiempo fomenten habilidades de pensamiento crítico, creatividad y capacidad de resolución de problemas.
On the Vulnerabilities of the Northern Sea Route’s Maritime Transportation System
Authors: Gunnarsson Björn
Published: June 2024

This study analyses several vulnerabilities in the maritime transportation system of the Northern Sea Route (NSR). The vulnerabilities discussed are already impacting transport and logistics operations on the NSR. These vulnerabilities have greatly increased as a result of Western technological and economic sanctions on Russia and the subsequent departure of Western companies from Russia, where they were previously providers of critical supplies, logistics services, and investments. The cumulative impacts of these vulnerabilities will make the NSR maritime transportation system less efficient and reliable and more prone to failures, reducing operational and environmental standards, impacting safety and increasing the environmental impact of NSR shipping. Russia needs to find suitable replacements for Western technology and services. Chinese companies will likely try to fill the gap left by the departure of Western companies to promote the continuous production of Russian Arctic commodities for export to China.
Exclusive Disjunctions With Three Disjuncts from First-Order Predicate Calculus
Authors: López Astorga Miguel
Published: June 2024

First-order predicate logic seems to be incompatible with the way people understand embedded exclusive disjunctions with three disjuncts. In classical logic, an exclusive disjunction with three disjuncts holds when the three disjuncts hold. However, it is hard to note that for people. The theory of mental models can explain this fact. According to that theory, individuals tend to process embedded exclusive disjunctions with three disjuncts intuitively. Thus, they only consider possible situations in which just one of the disjuncts is the case. The present paper tries to explain this problem within first-order predicate logic. The main point is that, in the latter logic, in inferences having, as its first premise, an embedded exclusive disjunction with three disjuncts, and, as its second premise, the first disjunct of that very exclusive disjunction, it is possible to infer none of the other two disjuncts.
Mereología y teoría de la verdad en la fenomenología temprana de Edmund Husserl
Authors: Guerrero Santelices Yuri Andrei
Published: June 2024

En la fenomenología temprana de Edmund Husserl se encuentra una distinción epistemológica fundamental entre lo real y lo ideal. Tal distinción constituye el fundamento de la crítica del conocimiento; así, por ejemplo, el problema de la correlación entre la conciencia y el mundo sería un caso paradigmático de tal diferencia. Asimismo, la conexión esencial entre el orden de la vivencia de la verdad y la verdad misma sería otro modo de formular nuevamente tal distinción. Si bien Husserl ofrece diversos argumentos a favor de la diferencia entre lo real y lo ideal, al mismo tiempo afirma que tal distinción es, por una parte, infranqueable, en la medida en que ambos ámbitos estarían separados por un abismo radical; pero, por otro, postula una eventual relación entre lo real y lo ideal. Por medio de una revisión de los textos tempranos de Husserl, se concluye que la teoría de los todos y las partes o mereología funge como doctrina fundamental que permite una comunicación entre lo real y lo ideal y, en esa misma medida, una explicación al problema de la verdad y su vivencia.
Alegoría y deseo de Dios en san Agustín
Authors: Calabrese Claudio César , Junco Ethel
Published: June 2024

Si la alegoría es fundamentalmente un modo de leer y de escribir (en suma, de pensar), que, en clave cristiana, se encuentra ligada a la salvación personal, esta actividad, en efecto, no puede quedar desvinculada obviamente del acto de fe, ni en lo fundamental del deseo de Dios, es decir, de aquel impulso que regresa al ser humano a su perfección. La sintonía siempre renovada entre hombre (mundo) Dios pone en movimiento dos aspectos: uno ascendente o delectatio Dei y otro descendente o cupiditas mundi. No hay lectura sin deseo, ni deseo que no se consuma como búsqueda de Dios.
periferia é protagonista
Authors: Rodrigues Ana Maria dos Santos
Published: June 2024

Este artigo é mais do que um relato de estudo, é um ato. Um ato de romper o silêncio, de erguer a voz e ecoar as lutas interseccionais que, por vezes, são silenciadas e segregadas. É um alerta por mudança, um chamado à consciência e à visibilidade. Aqui, subverte-se a narrativa hegemônica da lógica colonial, que fragmenta e desvaloriza as diversas frentes de luta e busca construir pontes por meio da tecnologia, especialmente das Inteligência Artificial.
Confusões e dilemas da antropomorfização das inteligências artificiais
Authors: Röhe Anderson , Lucia Lucia
Published: June 2024

Uma das principais razões de confusões, que rondam a compreensão daquilo que a Inteligência Artificial Generativa (IAGs) é ou não capaz de realizar, consiste em tomá-las à imagem e semelhança dos humanos, como se fossem, inclusive capazes de sentimentos ou como se elas próprias fossem racistas. Diante disso, este artigo visa debater quais os limites das IAGs e qual o papel que os humanos desempenham no uso que fazem delas. O resultado esperado é desmistificar a eficácia das IAs para a detecção de emoções ou para comportamentos éticos, sobretudo em relação aos cuidados a serem tomados em ambientes vulneráveis como a sala de aula.
Deusas e mulheres nos epigramas amorosos de Rufino
Authors: Torres Milton Luiz
Published: June 2024

Este é um breve estudo de alguns epigramas de amor do quinto livro da assim chamada “Antologia Palatina”, especialmente os poemas em que Rufino, um dos poetas mais profícuos (embora pouco conhecido) daquela antologia, contrasta e compara suas musas com as deusas. Para isso, recorre-se a uma metodologia comparativa em que, após uma breve introdução ao epigrama como forma literária e ao quinto livro da “Antologia Palatina”, oferece-se a tradução dos oito poemas de Rufino (que é um representante ideal da variedade de temas e do tratamento dado ao amor na Antologia Palatina) em que ocorre a justaposição de figuras femininas, quer envolvendo deusas, quer não. Afrodite e Palas Atena são o principal objeto de comparação, explícita ou implícita. A análise aponta para a óbvia conclusão de que o poeta recorria a esse artifício quando queria exaltar certas qualidades de suas musas, mas revela também que o teor das comparações nem sempre é cavalheiresco.
TRAÇANDO PERCURSOS INTERCULTURAIS PARA A COMPREENSÃO DO SER BRASILEIRO
Authors: Borges Sellan Aparecida Regina
Published: June 2024

Este artigo tem por objetivo apresentar uma breve síntese das contribuições da professora Regina Célia Pagliuchi da Silveira para a área do ensino de língua portuguesa, sobretudo na perspectiva de língua estrangeira (PLE). Trata-se de uma tentativa de registrar, em poucas páginas, parte do muito que realizou no ensino e na pesquisa, ao identificar, no contexto que se desenhou especialmente na década de 1990, novas demandas, com novas exigências, colocando no cerne da pesquisa e do ensino de português para estrangeiros aspectos relacionados à identidade cultural e à perspectiva intercultural. Situamos brevemente o contexto em que considerações a respeito da pesquisa e do ensino de português língua estrangeira começaram a surgir na PUC-SP por orientações da professora Regina Célia, sintetizamos alguns conceitos relativos à identidade cultural e interculturalidade, registramos algumas pesquisas orientadas por ela as quais contribuíram para trazer uma visão sobre o brasileiro, como unidade, na grande diversidade cultural.
Economia digital e concorrência:
Authors: Pegoraro de Araujo Clayton Vinicius , Ramos Garcia Junior Wagner Roberto , Jacobi Kölling Gabrielle
Published: June 2024

O aplicativo de transporte Uber é atualmente exemplo de modelo de economia compartilhada num ponto de revolução tecnológica com a quebra de barreiras no mercado digital. Mesmo com a resistência dos agentes de mercado na era da digitalização da economia é fato que existe uma realidade econômica, social e jurídica. Trata-se, em verdade, de um desafio no âmbito da regulação econômica e do próprio Direito Econômico em conciliar interesses dos agentes econômicos e dos consumidores. Diante desses desafios regulatórios e concorrenciais, o presente artigo se propõe a apresentar as principais inovações trazidas especificamente no mercado individual de passageiros, na concorrência entre os serviços de transporte via aplicativo Uber e o tradicional serviço de táxi, utilizando os métodos analítico e histórico descritivo para responder o seguinte questionamento: quais as principais inovações trazidas pelo aplicativo Uber no mercado individual de passageiros? Por fim, o artigo apresenta de forma didática um comparativo entre ambos os serviços e seus aspectos concorrenciais.
Utopia como Revolta Romântica
Authors: Santos Jonathan , Belfort Pedro
Published: June 2024

Este artigo demonstrará que o poema Ode to a Nightingale, do poeta romântico John Keats, forneceu ao romance utópico News from Nowhere (Notícias de Lugar Nenhum), de William Morris, um modelo em que a utopia se desenrolou. Para tanto, passar-se-á pelo ambiente histórico-intelectual de Morris e do movimento romântico, pela discussão sobre o conceito de Romantismo e pela discussão sobre a historicidade do conceito de utopia e da noção de tempo ali envolvida.
Emergência Climática e El Niño
Authors: Amorim Marcela Araujo de
Published: June 2024

Parte da região do nordeste do Brasil, é nomeada de semiárido devido a sua característica biofísica, de secas e uma predominância de espécies de arvores arbustivas e herbáceas que a classifica como o bioma caatinga. Segundo dados do Instituto Brasileiro de Geografia e Estatística - IBGE a região Semiárida do país, contém uma extensão total de 982.563,3 km², sendo 89,5%, da região do nordeste, estendendo-se aos estados como Maranhão, e o Estado de Minas Gerais, situados na Região Sudeste. O Nordeste possui um longo histórico de grandes secas, de acordo com Melo (1999) ao passar dos anos e com a criação de novas tecnologias, passa-se a saber que a ocorrência de secas no Nordeste estava ligada ao fenômeno do El Niño. O El Niño e La Niña são fenômenos climáticos que ocorrem no Oceano Pacífico e afetam o clima global. O El Niño envolve o aquecimento das águas do mar, enquanto a La Niña envolve o resfriamento. Ambos têm impactos significativos nas condições meteorológicas ao redor do mundo e são monitorados de perto por cientistas e especialistas em clima. El Niño é um fenômeno meteorológico de escala global, resultante do aquecimento diferenciado do Oceano Pacífico, provocando alterações no regime de precipitações atmosféricas em várias partes da terra. No Brasil, ocorre uma redução de chuvas nas regiões Norte e Nordeste, e um aumento na região Sul, em geral, o El Niño, embora fraco, no ano de 1992-93, afetou a vida de 8 milhões e 500 mil pessoas (DE MELO, 1999).
Esta pesquisa tem como metodologia principal a revisão bibliográfica de textos que relatam os efeitos do El Niño no Nordeste, chegando à conclusão de que a emergência climática é um sinal totalmente vermelho e perigoso em anos de El Niño. Por fim, mapeia-se ações e projetos que estejam atuando no Nordeste e que estejam pensando em como se adaptar aos efeitos que o El Niño pode causar futuramente. Além disso, elenca-se quais são os principais atores que atuam na região, visando à adaptação e à segurança das comunidades locais em relação às mudanças climáticas.
Säveltaiteilijat kotioloissaan: Kerttu Wanne, Astrid Joutseno ja 1930-luvulla pilkahteleva outous
Authors: Joutseno Astrid
Published: June 2024

Tässä artikkelissa nostan esiin viulisti Kerttu Wanteen (1905–1963) ja pianisti Astrid Joutsenon (1899–1962). He olivat säveltaiteilijoita ja elämänkumppaneita, jotka suomalainen musiikinhistoria on unohtanut. Elinaikanaan Wanne ja Joutseno olivat tunnettuja kansainvälisiä ammattitaiteilijoita. Joutseno on myös isoisotätini. Artikkelissa analysoin 1930-luvulla Wanteesta ja Joutsenosta kirjoitettuja suomalaisia sanomalehtiartikkeleita syventyen siihen, miten naisten taiteilijuus ja saman sukupuolinen elämänkumppanuus kerrotaan ja merkityksellistään. Pohdin myös aukkoja, sitä mikä jää vaille ilmaisua tai kirjoittuu hämärretysti, rivien välissä. Lähestymistapani pohjaa elämäkirjoitusteoriaan ja praktiikkaan sekä queer-tutkimuksen käsitteistöön. Kehitän queer-elämäkirjoituksellista positiota suhteessa historialliseen aikaan, sekä esitän argumenttini nykykieliselle queer-tulkinnalle ja elämäkirjoitukselle queeristä menneisyydestä ja tulevasta huolehtimisena.
Avainsanat: elämäkirjoitus; queer-arkisto; musiikin queer-historia; taiteilijanaiset; kumppanuus
Abstract
In this article I highlight Finnish musician-artists and life partners violinist Kerttu Wanne (1905–1963) and pianist Astrid Joutseno (1899–1962). They have been long forgotten in the Finnish history of music. During their lives Wanne and Joutseno were well-known professionals with international careers. Wanne was also a popular poetry and aphorism writer and Joutseno a piano pedagogue. In addition, Joutseno is my great aunt. This article analyzes Finnish newspaper articles about Wanne and Joutseno, written and published in the 1930s. I ask how being artists as women and being same gender life partners is portrayed and given meaning to. I also address silences, what remains without expression or is written in-between the lines. My methods rely on life writing theory and practice as well as queer theoretical concepts. I develop a queer life writing position in relation to historical time, arguing that contemporary queer interpretations and life writing about the queer past are necessary for taking care of the future.
Keywords: life-writing; queer archive; queer history of music; artist women; partnership; kinship