bluuebunny/crossref_metadata_2025 huggingface dataset:
COMPARISON BETWEEN RAPID AND SLOW CRYOPRESERVATION PROTOCOLS FOR RAM SEMEN
Authors: Ba-Awadh Hani A. , Olarinre Isiaka O. , Alowaimer Abdullah N. , Saadeldin Islam M. , Swelum Ayman A.
Published: February 2023

Information regarding adequate freezing protocols of ram semen considering freezing distance and time during cryopreservation has not been adequately reported. Therefore, this study aimed to compare two freezing protocols for Najdi ram's semen. In the rapid freezing protocol, the straws were frozen at 5 cm over the surface of liquid nitrogen for 15 minutes. While in the slow freezing protocol, the straws were frozen at 8 cm over the surface of liquid nitrogen for 20 minutes. The semen was collected from five rams and extended with tris egg yolk glycerol cryodiluent. The extended semen was chilled slowly to 50C within two hours and equilibrated for two hours before being frozen on the liquid nitrogen vapor and cryopreserved at -1960C. There was no significant (P >0.005) effect of the freezing protocol on the sperm’s total motility, plasma membrane integrity, DNA integrity, and abnormalities. However, the vitality, fast progressive motility, straight-line velocity, average pathway velocity, linearity, and wobble were significantly higher in rapid freezing than in slow freezing protocol. In conclusion, cryopreservation of ram semen using rapid freezing (5 cm for 15 mins) protocol was better than slow freezing (8 cm for 20 mins) protocol regarding post-thawing semen quality.
Key words: freezing protocol; cryopreservation; egg yolk; ram; semen
ANTI-FIBROTIC AND ANTIOXIDANT AMELIORATIVE EFFECTS OF NARINGENIN AGAINST THIOACETAMIDE INDUCED LIVER FIBROSIS
Authors: Ali Haytham A. , Mohamed Afifi
Published: February 2023

Liver fibrosis still life-threatening problem and searching out ameliorative products motives many scientists, so this work evaluated the anti-fibrotic and antioxidant role of naringenin (NAR) against thioacetamide (TAA) induced liver fibrosis. Fifty adult male albino rats randomly divided into 5 groups (10 each); the first kept as control; the second treated I/P by 200 mg/kg TAA twice a week for 8 weeks; the third was gavaged daily with 50 mg /kg/ b.wt of NAR for 8 weeks; the fourth was co-treated by TAA and NAR while the fifth was treated with TAA for 8 w then gavaged daily by NAR for 1 month. TAA administration significantly increases the hepatic cell enzymes (ALT, AST, ALP and GGT) in the serum referring to hepatic cell destruction with an increase in hepatic MDA with a reduction in GSH concentrations, antioxidant enzyme activities as well as down regulation of their expression levels. NAR administration either with or after TAA ameliorates this effect suggesting its antioxidant ability. In the fibrotic pathway, TAA treatment up-regulates the expression levels of fibrogenic biomarkers (TGF-β, collagen 1α and fibronectin) genes while NAR down-regulates these genes suggesting its anti-fibrotic ability. Histopathological analysis confirms the biochemical results. In conclusion, NAR ameliorates the deleterious effect of TAA through its antioxidant and anti-fibrotic abilities.
PREVALENCE OF MULTIDRUG RESISTANT SHIGA TOXIN PRODUCING E. coli IN THE MILK OF CATTLE, BUFFALOES, AND CAMEL
Authors: Abdullah F. Alsayeqh  , Asmaa S. M. Mohamed  , Rehab E. Mohamed  , Nermin Awad Ibrahim  , Eman Hamdy  , Mohamed E. Alnakip
Published: February 2023

Regarding high morbidity, mortality, and production losses, fungi infections have their importance among infectious illnesses and seem to be one of the main challenges facing poultry producers. This study aims to identify the genotypic characteristics of some fungi isolated from poultry. To reach this end, in El-Gharbia Governorate, Egypt, a total of 210 birds with a history of respiratory distress were randomly selected from a variety of private farms and hatcheries. The birds were sacrificed; tissue pieces were collected. In addition, a total of 87 samples of the poultry surroundings including 40 samples of poultry ration, 14 bedding materials, 4 air samples, and 29 water samples were collected. Using traditional fungal isolation, four fungal species were recovered, namely, Aspergillus niger, Aspergillus flavus, Cladosporium perangustum, and Penicillium chrysogenum. PCR was performed by fungus-specific universal primer pairs (ITS1 and ITS4) to identify and describe the genotype of isolated fungi. All examined isolates' ITS1-5.8SrDNA regions could be amplified. A purified PCR product was sequenced according to the Emerald Amp GT PCR master mix. This was initially performed to establish sequence identity to GenBank accession numbers. The rRNA gene for 5.8 sRNA divides the two ITS sections, which are situated between the 18S and 28S rRNA genes. ITS-1 gene sequence of the isolated Cladosporium perangustum (GeneBank accession number was OM 407392). The Sequence of the ITS-1 of isolated Penicillium chrysogenum (GeneBank accession numbers for studied nucleotide sequences were OM407401; OM407402; OM403685, and OM403686). For the examined nucleotide sequences, the GeneBank accession number for the ITS-1 internal transcribed spacer region of single Aspergillus niger was OM407391. GeneBank accession numbers for the isolated Aspergillus flavus ITS-1 sequence examined nucleotide sequences were OM403676, OM403677, and OM403678. In conclusion, genotypic characterization confirmed the phenotypic traditional fungal identification in the present study.  Aspergillus species are the major fungi associated with birds in Egypt farms. The predominantly identified species were Aspergillus flavus and Penicillium chrysogenum.
Key words: phenotypic; genotypic; molecular; fungi; poultry
MORPHOLOGY OF THE DROMEDARY CAMEL STOMACH WITH REFERENCE TO PHYSIOLOGICAL ADAPTATION
Authors: Ibrahim Zarroug H. , Almundarij Tariq I.
Published: February 2023

Dromedary camels (Camelus dromedarius) are adapted to their desert habitat where they are able to survive and reproduce despite very high temperatures, little vegetation, and limited water availability. The mechanism of thermoregulation in camels is highly efficient, which makes them maintain the appropriate body temperature to carry out their physiological activities. Compared to other mammals, camels are environmentally tolerant as they can be bred for milk and meat production in areas with scant natural resources depending on their unique physiological, anatomical and behavioral characteristics. The camel's digestive system has unique morphological features that make it highly adapted to its natural environment. Although the stomach of camels is divided into compartments, as in ruminants, they are referred to as pseudo-ruminants because they do not have the clearly divided four-chambered stomach found in true ruminants. However, their stomach is larger and more efficient in dealing with dry, tough, and fibrous food. Therefore, the current study aimed to review the gross anatomical and histological peculiarities and characteristic features of the dromedary camel stomach with respect to their physiological importance. The morphological characterization of the dromedary camel stomach might elucidate the functions of its different compartments. Thus, this review could add to our understanding of the physiology of the digestive system in dromedary camels.
RABBIT MEAT AS A POTENTIAL SOURCE OF STAPHYLOCOCCUS AUREUS AND SALMONELLA SPP.
Authors: Morshdy Alaa Eldin M. A. , Alsayeqh Abdullah F. , Aljasir Mohammed F. , Mohieldeen Hassan , Gamal El-Abody Shymaa , Elsayed Mohamed Mohamed , Darwish Wageh Sobhy
Published: February 2023

Rabbit meat and offal are considered valuable sources of high biological value animal protein. Rabbit meat is rich in essential amino acids, low in cholesterol, and contains considerable amounts of trace elements such as calcium, magnesium, and zinc. However, the potential contribution of rabbit meat and offal in the transmission of foodborne pathogens such as Staphylococcus aureus (S. aureus) and Salmonella spp. is neglected. Therefore, this study was conducted first to investigate the prevalence rates of S. aureus and Salmonella spp. in the retailed rabbit meat at Sharkia Governorate, Egypt. Second, serological identification of the isolated bacteria was followed. Detection of S. aureus-enterotoxins and Salmonella-virulence-associated genes was also done using PCR. Antimicrobial susceptibility testing of the recovered bacterial isolates was additionally examined. The acquired results showed that 17% of the investigated samples of rabbit meat contained S. aureus. Where S. aureus was isolated from the investigated rabbit's breast, thigh, liver, and kidney at 20%, 24%, 12%, and 12% of each, respectively. Salmonella spp. was isolated at 13%. Salmonella spp. was isolated from the investigated rabbit thigh, liver, breast, and kidney at 16%, 16%, 12%, and 8%, respectively.  Four different strains of Salmonella spp namely, S. Typhimurium, S. Kentucky, S. Virchow, and S. Infantis were recovered in the current study. The recovered S. aureus and Salmonella spp. harbored enterotoxins and virulence attributes with multidrug resistance. Therefore, strict hygienic measures should be followed during the processing and handling of rabbit meat and offal.
Numerical analysis of the contribution of side resistance to caisson bearing capacity
Authors: Pereira Bárbara , Garcia Jean
Published: February 2023

The use of deep foundations is a common practice in geotechnical civil engineering designs, in which the bearing capacity of these foundations occurs by side resistance, tip, or through the combination of both. In the case of caisson, the bearing capacity is often obtained by considering only the resistance of the lower end due to its bell-shaped geometry, neglecting the skin friction resistance of the shaft, which may represent an oversizing in some cases. In this context, this paper analyzed the behavior of nine caisson prototypes laid at 10 m, 15 m and 20 m deep. At each depth, three types of caissons were analyzed, with and without an expanded base, and a third type with deformable material at the top of the base. The axisymmetric numerical analyses were conducted by using the finite element method considering an isotropic medium. Thus, it was found that with increasing depth, the skin frictional resistance of the surrounding soil of shaft contributes significantly to the bearing capacity of the caisson suggesting that little load would reach the base of the caisson in situations that would negligible the side resistance of the shaft in the design phase. This may be an important consideration in foundation design using caisson, as it would reduce risks to human life, as well as reduce material consumption and the generation of carbon released into the atmosphere.
Maximum shear modulus estimative from SPT for some Brazilian tropical soils
Authors: Rocha Breno , Silva Bruno , Giacheti Heraldo
Published: February 2023

Maximum shear modulus (G0) has been used in various geotechnical jobs (e.g., seismic site assessment, machine vibration and pile driven). Laboratory and in situ determination of G0 is not a current practice in Brazil. G0 can be estimated from empirical correlations based on in situ tests like Standard Penetration Test (SPT) and Cone Penetration Test (CPT) in the preliminary design phase. Several empirical correlations to estimate G0 from SPT N value have been developed and are available in the literature. However, most of these correlations were established based on experience with well-behaved soils formed in temperate and glacial zones, which may not always be used for tropical soils. This paper assessed and discussed the applicability of some correlations for G0 estimative from SPT data in lateritic and saprolitic soils. The classical correlations for sedimentary soils underestimated G0 of tropical soils. After updating the database, the tropical soils correlations reasonably estimated G0 for the lateritic ones, which was not the case for the saprolitic soils. It was observed that differentiating the soils only as lateritic or saprolitic was not adequate for a good G0 estimate for the saprolitic sandy soils. It was found that only the lateritic soils correlation can be used with caution as a preliminary attempt to estimate G0 from SPT N value in soils with similar characteristics to the ones presented in this paper.
Closed-form consolidation solutions for known loading functions
Authors: Carneiro Raphael , Guerra Karl , Romanel Celso , Gerscovich Denise , Danziger Bernadete
Published: February 2023

In engineering practice, loading varies with time. However, the classical one-dimensional theory of consolidation assumes the stress increase is instantaneously applied. Many approaches to the problem of time-dependent loading have been proposed over the years, from approximate methods to full developments of differential equations. The paper presents a simple method for finding a closed-form consolidation solution for time-dependent loading without the need for differential equations. Two sets of general equations were derived for both excess pore pressure and average degree of consolidation. Equations were solved for linear, parabolic, sinusoidal, and exponential load functions. Stepped and cyclic loads were also addressed and a numerical solution was developed to verify the obtained result. The method proved to be easy to apply and provides solutions with great simplicity. A case study of non-instantaneous loading on soft clay was also analyzed, and settlement prediction showed good results when compared to readings of the settlement plates.
Association between poor sleep hygiene practices, sleep deprivation, and their effects on medical students of Karachi: A cross-sectional study
Authors: Khawaja Uzair , Wasim Momal Ahmad , Abid Ali Fatima
Published: February 2023

Objectives: This study was conducted to investigate the poor sleep hygiene practices of medical students, causing sleep deprivation, and any negative effects on physical and cognitive health of the adult population in Karachi.
 Participant: The participant for this study were the medical students enrolled in six medical colleges in Karachi during 2021-2022.
 Methods: The data was collected from 200 medical students using questionnaire based survey. Data was analysed using SPSS version 20. t-test and Chi-square (χ2) test was used for the best data analysis. P-value of <0.05 was considered statistically significant in case of comparative analysis.
 Results: The majority students did not follow sleep hygiene protocols. Concerning the psychological and cognitive effects of poor sleep hygiene practices, more than 76% participants reported feeling sleep deprived, and experienced physical symptoms.
 Conclusion: Our findings support the use of sleep-hygiene awareness as a prevention strategy to improve university students’ sleep practices, preventing sleep deprivation.
Underpinnings of gender bias within the context of work-life balance
Authors: Sonal Sisodia  , Sarvesh Raj Rocque
Published: February 2023

A significant quantity of stress and anxiety is caused, as a consequence, as a result of employees having to try to balance the demands of work and family in their lives, which results in a significant amount of job-related stress and anxiety. Work-related conflicts are a very common occurrence among employees as the result of job stress, making it one of the biggest problems in the world for employees as a result of job stress, due to the fact that there are so many types of conflicts. It is true that employees who are able to maintain a balance between their work and family lives have the ability to apply the positive behaviors they have learned from their personal lives to their work lives, but the authors of this paper found out by conducting a survey that there is still room for improvement in this area. As part of the literature review, a number of studies related to gender have been conducted over the past few years, the majority of which have focused on the impact of gender on the work-family balance in the workplace. The availability of several gender-related studies on this subject has been noted in the literature, and several of them are in progress. A lot needs to be determined in terms of whether or not men find it difficult to balance work and family responsibilities in the same way as women, or if they in fact are experiencing a bit of an advantage in this sense over their female counterparts.
Financial analysis of accountability at the regional financial and asset agency (BKAD) of the south Sulawesi provincial government
Authors: Arianto Taliding  , Oktovianus Sauw  , Wiwin Anggriani Salawali  , Vira Tandiawan  , Melda Gienardy  , Andi Dyna Riana  , Arfandi SN  , Muliana
Published: February 2023

Government accountability is manifested in the adjustment of the presentation of financial statements to government accounting standards as the basis for providing opinions on government financial statements. This study aims to analyze financial reports on accountability in government agencies in the Regional Finance and Assets Agency (BKAD) of the South Sulawesi Provincial Government. The data used in this study are primary data with qualitative research methods using interview guidelines. The results of this study indicate that there is an effect of financial reports on accountability in government agencies in the Regional Finance and Assets Agency (BKAD) of the South Sulawesi Provincial Government where financial reports are reported in full and in accordance with government accounting standards (SAP), on time and in accordance with regulations so that the Agency Regional Finance and Assets (BKAD) received a fair predicate without exception (WTP) in the SKPD for the 2021 fiscal year.
A case of possible Susac syndrome with avascular necrosis of hip
Authors: Rajesh Verma  , Rajarshi Chakraborty
Published: February 2023

Susac syndrome (SuS) is a rare autoimmune micro-angiopathic endotheliopathy. The diagnosis of SuS is a challenge to neurologists because of the diversity of symptoms and rarity of occurrence of classical triad of SuS. In this context, a plethora of immunological/demyelinating disorders can mimic the features of neurological manifestations of SuS. The detection of snowball corpus callosal lesion is unique to SuS. A high degree of suspicion is the key to diagnosis and early immunomodulator therapy can prevent catastrophic disabilities. The use of steroid-sparing medications should be advocated wherever possible. In this case report, we tried to explore a 20 year old female with headache, seizure, irritability, blurring of vision with right hip pain and emphasize the need for awareness of this rare entity along with high element of suspicion for detection of such disorders.
The functions of veterinary epidemiology in public health
Authors: Muhammad Shuaib Shaffi
Published: February 2023

This paper aims to describe the core functions of veterinary epidemiology in public health to understand the ultimate objective of preventing, mitigating, or eliminating zoonotic diseases in susceptible populations. However, the ideas came from a variety of sources. The field of veterinary medicine has significantly contributed to many aspects of public health, including human and environmental wellness, animal welfare, comparative and basic medical study, and the mitigation of zoonotic illness. Veterinary epidemiology, one of the disciplines that make up veterinary public health, is particularly concerned with disease surveillance, response, and prevention. In the veterinary study, epidemiological methods examine diseases' dynamics, prevalence, and causes in populations of interest. The ability to better comprehend hazards and how to prevent widespread sickness is now possible for veterinary epidemiologists. Veterinarians can help advance public health studies and policies by employing various methodological approaches and collaborating with networks of expert epidemiologists in the field.
English for specific purposes in Spain: Project based learning classroom proposal in vocational education
Authors: Macías Manuel
Published: February 2023

Society is constantly changing, and education should change at the same time. However, innovation in education is slower than changes in society. Active methodologies are of interest because they are one of the alternatives to linear, traditional and uniform methodologies that encourage reflection, motivation and creativity among other elements. In addition, they cater for different educational settings and the diversity found within the classroom. It is an interesting approach that is a far cry from traditional education in language teaching. The main objective of this paper is to explore whether project-based learning (hereinafter PBL) is a good practice for young vocational students. The problem to be addressed here by this methodology is the lack of motivation and involvement of vocational students in the subject of English–or English for specific purposes. To address this matter, we proposed a seven-session class design following the PBL methodology. This class proposal is designed following criteria that meet the current legislation and normative in Spain (LOMCE and LOMLOE laws) and criteria that meet the standards of European vocational formation and English for specific purposes (addressing the CERFL). Analyzing the results obtained, we can state that PBL seems to be an effective methodology with significant results especially in the field of teaching and learning ESL and EFL vocabulary.
Factores de riesgo psicosocial y Síndrome de Burnout en los Agentes de Seguridad Penitenciaria en el CPL Mujeres Quito - Psychosocial risk factors and Burnout Syndrome in Penitentiary Security Agents in Quito Women's LDC (Liberty Deprivation Center)
Authors: Estrella Lidioma Shirley Gissella , Rodríguez Vásconez Alfonsina Isabel , Suasnavas Bermúdez Pablo Roberto , Vilaret Serpa Aimee
Published: February 2023

Las condiciones y el entorno hostil y violento por parte de las personas privadas de libertad (PPL) en el Centro de Privación de Libertad Mujeres Quito, hace que el trabajo de los Agentes de Seguridad Penitenciaria (ASP) se encuentre expuesto a altos niveles de riesgos psicosociales y estrés laboral, desarrollando afecciones propias de este tipo de riesgo y Síndrome de Burnout. El objetivo de la investigación identificar la prevalencia del Síndrome de Burnout y los factores de riesgo psicosocial presentes en los Agentes de Seguridad Penitenciaria (ASP) para la futura implementación de medidas correctivas que permitan la prevención de riesgos psicosociales y los problemas asociados con el Síndrome de Burnout que trascienden en el contexto social, familiar y laboral; dentro de la metodología se trabajó con tres instrumentos el Cuestionario de valoración de exposición a Factores de Riesgo Psicosocial Q10-FRP, entrevista semiestructura del Protocolo PSICOVS2012 y el cuestionario de Maslach Burnout Inventory (MBI). Los resultados del Q10-FRP mostraron en su nivel de intervención 1 que un 14,5% de los ASP se encuentran con riesgo muy elevado y el 27% con riesgo elevado en factores de riesgo psicosocial; mientras que en la entrevista semiestructurada respecto a los acontecimientos externos y/o laborales el 15% de la muestra presentó afectación en ambos criterios y tan solo en el 10% de Agentes de Seguridad Penitenciaria se consideró causas externas de afectación. Con respecto al instrumento MBI se determinó que el 10 % en los ASP presenta Síndrome de Burnout y el 35% corre riesgo de desarrollarlo. Se concluyó que el estudio brinda un aporte significativo para futuros análisis dentro y fuera del país en el contexto penitenciario, al existir poca información con respecto a este ámbito.
Miocardiopatía periparto, una complicación obstétrica: a propósito de un caso clínico - Peripartum cardiomyopathy, an obstetric complication: about a clinical case
Authors: Peralta-Merelo Sara , León-Alonso Katherine , Montero-Farías Daniel , Mendoza-Moreira Ruben , Escobar-Segovia Kenny
Published: February 2023

La miocardiopatía periparto es una patología de presentación atípica que implica todo un reto para el equipo médico, tanto en el diagnóstico como en el tratamiento y no solo por lo complejo del mismo sino también porque presenta una elevada mortalidad tanto para la madre como para el producto, haciendo imperioso su pronto manejo para evitar complicaciones fatales. Es por este motivo que se presenta el caso clínico de una fémina de 30 años en su puerperio, que es referida al centro hospitalario por un aparente cuadro séptico con evolución tórpida a pesar del tratamiento antibiótico, valorada en el hospital donde es diagnosticada de insuficiencia cardiaca con fracción de eyección severamente disminuida, y la cual a pesar del tratamiento no presentó mejoría ni recuperación de la función cardiaca, posiblemente por el diagnóstico y las medidas que se tomaron tardíamente.
Regions with Low Financial Sustainability: Analysis and Enhancement of Development
Authors:   Financial University under the Government of the Russian Federation, Moscow, Russian Federation, Stroev Pavel V. , Pivovarova Olga V. ,   Financial University under the Government of the Russian Federation, Moscow, Russian Federation, Sheozhev Khasanbi V. ,   Financial University under the Government of the Russian Federation, Moscow, Russian Federation, Dudnik Anna I. ,   Financial University under the Government of the Russian Federation, Moscow, Russian Federation
Published: February 2023

This article presents an analysis of the socio-economic development and fiscal position of the subjects of the Russian Federation with low financial sustainability. The existing domestic and foreign approaches to understanding the concept of "financial sustainability of territory" are analyzed. It is proved that the regions with low financial sustainability include the subjects of the Russian Federation with a high level of gratuitous receipts in the structure of the regional budget and lagging behind the average Russian regions in terms of basic economic parameters. The relevance of the study lies in identifying problems that hinder the economic growth of such regions, as well as in developing measures to improve interbudget relations. ITo carry out the analysis and identify the specifics of management of these territories, the authors identify a group of regions with low financial sustainability, having different geographical location and degree of intensity of this problem (the Republics of Mordovia and Tyva, the Trans-Baikal Territory, the Pskov and Oryol Regions, the Jewish Autonomous Region), and apply an original methodological approach based on the assessment of the socio-economic situation and the fiscal position. As a result, both general socio-economic (depopulation, low wages, unemployment, depreciation of fixed assets, low investment and innovation activity) and fiscal (budget imbalance, low level of financial independence, debt burden) problems of these subjects of the Russian Federation, as well as problems specific to each of them, are identified. Measures to enhance economic development and growth of the income base of regions with low financial sustainability are proposed, and suggestions for improving regulatory legal acts in the field of state regional management are formulated.
Sintesis 4'-metoksi-4-nitrokhalkon dari 4-nitrobenzaldehida dan 4- metoksiasetofenon dengan Teknik Grinding (Kolokium Kimia)
Authors: Nugroho Iman Sri
Published: February 2023

ABSTRAKIman Sri Nugroho. K3316026. SINTESIS 4'-METOKSI-4-NITROKHALKON DARI 4-NITROBENZALDEHIDA DAN 4-METOKSIASETOFENON DENGAN TEKNIK GRINDING. KolokiumKimia. Surakarta: Fakultas Keguruan dan Ilmu Pendidikan. Universitas SebelasMaret. Januari 2021.Penelitian ini bertujuan untuk mensintesis senyawa 4'-metoksi-4-nitrokhalkon. Senyawa khalkon dapat disintesis melalui reaksi kondensasi aldolClaisen-Schmidt menggunakan turunan benzaldehida dan asetofenon. Padapenelitian ini sintesis senyawa 4'-metoksi-4-nitrokhalkon dilakukan denganmenggerus 4-nitrobenzaldehida dan 4-metoksiasetofenon menggunakan katalisNaOH selama 30 menit. Kristal produk dimurnikan dengan rekristalisasimenggunakan pelarut etil asetat lalu kemurnian kristal dicek menggunakan KLT.Karakterisasi produk menggunakan GC-MS.. Hasil penelitian menunjukkan bahwa senyawa 4'-metoksi-4-nitrokhalkontelah berhasil disintesis dari reaksi antara 4-metoksiasetofenon dan 4-nitrobenzaldehida dengan katalis NaOH dengan teknik grinding. Kristal produkyang dihasilkan berwarna oranye kemerahan dengan massa 2,853 gram (rendemen94,683%). Hasil GC-MS menunjukkan bahwa pada filtrat hasil rekristalisasiterdapat dua puncak yang berarti mengandung dua senyawa. Puncak pertamamemiliki luas area 20,76% dengan nilai m/z puncak ion molecular 150. Nilaitersebut sesuai dengan berat massa senyawa 4-metoksiasetofenon. Puncak keduamemiliki luas area 79,24% dengan nilai m/z puncak ion molecular 283. Nilaitersebut sesuai dengan berat massa senyawa 4'-metoksi-4-nitrokhalkonKata Kunci: khalkon, Claisen-Schmidt, grinding.
Differential Relationship Between Meditation Methods and Psychotic-Like and Mystical Experiences
Authors: Palmer Tim Neville , Kadri Kenza , Fakra Erick , Scholl Jacqueline , Fouragnan Elsa
Published: February 2023

Much work has investigated beneficial effects of mindfulness-based meditation methods, but less work has investigated potential risks and differences across meditation methods. We addressed this in a large pre-registered online survey including 613 mediators where we correlated participants’ experience with fifty meditation techniques to psychotic-like experiences - PLEs (e.g. hallucinations) as detrimental outcomes, and mystical experiences as beneficial outcomes. We found a positive correlation for both PLEs and mystical experiences with techniques aiming at reducing phenomenological content (‘null-directed’, NDM) or classified as non-dual or less embodied. In contrast, methods aiming at achieving an enhanced cognitive state also described as ‘attentional’ or strongly embodied, showed negative correlations with PLEs. Interestingly, participants’ subjectively perceived that all types of meditation techniques were preventative of PLEs but less so for NDM. This study provides important information for meditators about the relationship of different techniques with PLEs and the moderating influences of individual traits.
More than Words: Speech production in first episode psychosis predicts later social and vocational functioning.
Authors: Mackinley Michael , LIMONGI ROBERTO , Silva Angelica , Richard Julie , Subramanian Priya , Ganjavi Hooman , Palaniyappan Lena
Published: February 2023

Background: Several disturbances in speech are present in psychosis; however, the relationship between these disturbances during the first episode of psychosis (FEP) and later vocational functioning is unclear. Demonstrating this relationship is critical if we expect speech and communication deficits to emerge as targets for early intervention.Method: we analyzed three one-minute speech samples using automated speech analysis and Bayes networks in an antipsychotic-naive sample of 39 FEP patients and followed them longitudinally to determine their vocational status (engaged or not engaged in employment education or training - EET vs. NEET) after 6-12 months of treatment. Five linguistic variables with prior evidence of clinical relevance (total and acausal connectives use, pronoun use, analytic thinking, and total words uttered in a limited period) were included in a Bayes network along with longitudinal NEET status and Social and Occupational Functioning Assessment Scale (SOFAS) scores to determine dependencies among our variables. We also included clinical (Positive and Negative Syndrome Scale 8-item version (PANSS-8)), social (parental In review socioeconomic status,) and cognitive features (processing speed) at the time of presentation as covariates.Results: The Bayes network revealed that only total words spoken were directly associated with NEET and had an indirect association with SOFAS, with a second set of dependencies emerging among the remaining linguistic variables. The primary (speech-only) model outperformedmodels including parental socioeconomic status, processing speed or both as latent variables.Conclusion: impoverished speech, even at subclinical levels, may hold prognostic value and warrant clinical consideration when treating first-episode psychosis.
Sex Differences in Neuroendocrine, Sympathetic Nervous System, and Affect Responses to Acute Stress in Cannabis Users
Authors: Larson Eric , Moussa-Tooks Alexandra , Tullar Rachel , Bolbecker Amanda , O'Donnell Brian , Hetrick William P. , Wisner Krista
Published: February 2023

Cannabis is the most widely used illicit substance in the United States and is often reportedly used for stress reduction. Indeed, cannabinoids modulate signaling of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system. However, the role of biological sex in this interaction between cannabis use and stress is poorly understood, despite sex differences in neurobiological stress responsivity, endocannabinoid signaling, and clinical correlates of cannabis use. Frequent cannabis users (>3x/week, n=48, 52% male) and non-users (n=41, 49% male) participated in an acute psychosocial stress paradigm. Saliva was collected at eight timepoints and analyzed for hypothalamic-pituitary-adrenal (cortisol) and sympathetic (alpha-amylase) indices of stress responsivity, and estradiol at baseline. Subjective ratings of negative affect, including distress, were collected at three timepoints. Cannabis users showed blunted cortisol responsivity and lower alpha-amylase output overall compared to non-users, with no statistical differences between groups on overall negative affect reactivity. Aberrant stress responsivity in cannabis users was driven by females, with significant sex by time interactions for cortisol and alpha-amylase responsivity in cannabis users only. Female cannabis users demonstrated the greatest change in subjective distress across timepoints. Differences in stress responsivity were not explained by estradiol or distress intolerance. Biological sex may moderate multisystem stress responsivity in cannabis users. Paradoxically, female cannabis users showed the least physiological, but greatest subjective, responsivity to the stressor. Further research into sex differences in the effects of cannabis use is warranted to better understand mechanisms and clinical implications.
Identification of potential young talented individuals in the natural and life sciences: a bibliometric approach
Authors: Haunschild Robin , Bornmann Lutz
Published: February 2023

Identification of young talented individuals is not an easy task. Citation-based data usually need too long to accrue. In this study, we propose a method based on bibliometric data for the identification of potential young talented individuals. Since potential talent is defined in this study in terms of early publication performance, three different indicators and their combinations were used: We not only used (1) the number of papers in high-impact journals, but also (2) the total number of papers, and (3) the number of papers as a corresponding author. An older cohort with their first publication between 1999 and 2003 was used to find the most suitable indicator combination. Two additional indicators were used for the validation step: (1) the citation impact on the level of individual papers and (2) the number of papers that are linked to grants were used. The best performing indicator combination was applied to the time period 2007-2011 for identifying young potential talented individuals who published their first paper within this time period. We produced a set of 46,200 potential talented individuals.
Curriculum Management in Improving The Quality of Student Learning and Academic Achievement
Authors: Neliwati Neliwati , Hasanah Uswatun , Pringadi Retno , Sirojuddin Akhmad , Arif Muhamad
Published: February 2023

This research was conducted in relation to curriculum management in improving the quality of learning and academic achievement of students at MAS Insan Kesuma Madani in Namorambe. This research will use a qualitative method, namely the research is carried out in natural conditions (natural setting). The data sources for the nature of this research are divided into two groups, namely primary data sources and secondary data sources. The data collection technique that will be carried out is triangulation. From the findings in the field, that the curriculum planning process carried out in madrasas is in accordance with management theory, which starts from planning, implementation, and final results which will be closely related to the evaluation process of what is carried out from beginning to end. Improving discipline and improving the quality of human resources and Mas insan Kesuma Madani in Namorambe have carried out several curriculum implementation programs to improve the quality of learning and student academic achievement.
Estrategias de reproducción social de las unidades domésticas en sectores urbanos pobres El caso de la colonia Plan de Ayala en San Cristóbal de Las Casas, Chiapas
Authors:   Universidad Autónoma de Chiapas, Recinos Ruiz Roberto Iván
Published: February 2023

El presente artículo tiene como objetivo analizar la construcción de las estrategias de reproducción social de las unidades domésticas en sectores urbanos pobres. Como enfoque teórico se usó la teoría de reproducción social del sociólogo Pierre Bourdieu, la cual propone el análisis del habitus, capitales y estrategias de reproducción, como parte fundamental para comprender las relaciones sociales. Se aborda el problema desde lo espacial y social. La estrategia metodológica fue cuantitativa y cualitativa. Se utilizaron técnicas como la encuesta a través de un guion de cuestionario aplicado a sesenta y seis jefes del hogar y entrevistas semiestructuradas realizadas a un total de seis integrantes de la familia desde la primera hasta la tercera generación a partir de las formas y maneras en las que se reproducen social y espacialmente. Para ello, se tomó como eje de discusión el análisis de las estrategias educativas, sociales, sucesorias, económicas, de calidad de vida y vivienda. Dentro de los principales hallazgos resalta que las condiciones de los habitantes han mejorado en poca medida, sin embargo, dicha mejoría no ha sido suficiente como para satisfacer todas las necesidades básicas a plenitud.
Pelatihan Penggunaan Chatbot Sebagai Penyedia Informasi Di Museum Daerah Riau Sang Nila Utama
Authors: Nasution Arbi Haza , Monika Winda , Kausarian Husnul
Published: February 2023

Pada era society 5.0 lembaga memori seperti museum dan perpustakaan perlu mengimplementasikan teknologi informasi mulai dari digitalisasi koleksi hingga diseminasi informasi. Namun, pengembangan teknologi yang baru dilakukan oleh museum Sang Nila Utama sebatas pembuatan website dan sistem informasi yang bersifat satu arah. Sosial media merupakan wadah dua arah yang berpotensi besar digunakan untuk mendesiminasikan informasi mengenai museum Sang Nila Utama langsung ke smartphone masyarakat. Kegiatan pengabdian kepada masyarakat yang dilakukan berupa penyuluhan penggunaan aplikasi chatbot yang terintegrasis dengan Telegram. Peserta penyuluhan diberikan bekal untuk menambahkan basis data chatbot melalui aplikasi berbasis web dan dibimbing untuk menggunakan Telegram chatbot hingga cara untuk melakukan promosi kepada pengunjung museum agar dapat menggunakan fasilitas yang diharapkan dapat menarik minat masyarakat untuk menelusuri informasi yang tersedia. Berdasarkan hasil angket usability testing, seluruh peserta sangat setuju bahwa informasi yang tertera di aplikasi terorganisir, aplikasi mudah digunakan dan secara keseluruhan aplikasi menunjang proses diseminasi informasi di museum dengan baik dan optimal. Secara keseluruhan aplikasi bekerja sesuai dengan fungsi yang telah dirancang yang ditunjukkan dengan rata-rata nilai yang tinggi sebesar 4,48. Mitra merasa sangat puas dan merekomendasikan untuk kegiatan pengabdian serupa dilakukan secara berkala.
The Open Spaces of Literature vs. the Closed Spaces of Nation: the (Trans)national (Con)text of Contemporary American and Bosnian-Herzegovinian Literature(s)
Authors: Raljević Selma
Published: February 2023

In their individual categories and entities, both American and Bosnian and Herzegovinian literatures are more transnational in the 21st century than ever before in the history of the literature of both countries, or even in the history of world literature. The transnationality of both has been manifested in many ways through the history of the world as seen as an open space for mobility in both literatures, being in many respects opposed to the closed spaces of the “imagined communities” of the nation-states these literatures “belong to” in the national context. In addition, transnational American and Bosnian-Herzegovinian literature has been created on both sides as a joined and mutual, permuting and open space/category in both literatures. Hence, there are individual systems and spaces of Transnational American Literature(s) and Transnational Bosnian and Herzegovinian Literature(s), and there is a mutual category and a joined entity of Transnational American and Bosnian and Herzegovinian Literature(s) as part of the generic system of both trans/national works of literature. The special aim of the article is to contribute to the field of the study of Contemporary Transnational American, Bosnian-Herzegovinian, and American-Bosnian-Herzegovinian works of literature, emphasizing how the identities of authors and/or their books and then their modes of mobility, can defamiliarize and resist conventions and canon of “imagined communities”. In that context, the article also aims to benefit contemporary trans/national literary and cultural studies in their specificity and uniqueness in the United States and Bosnia and Herzegovina. Broader the world, examining the processes through which American and Bosnian-Herzegovinian literature become members of the “World Republic of Letters” and how this process is experienced and vice versa
Intersectional Law of Reading Women’s Diary: Subjectiveness of Expression, Power of Words, and Topos of Horrors of War
Authors: Omeragić Merima
Published: February 2023

The focus of this research paper is on post-Yugoslav women’s prose, or more precisely, the genre of diaries written by women which take the disintegration of Yugoslavia as their topic. This form of writing on the horrors of war distingushes itself through certain key attributes: female experience in itself needs to be articulated as the subject of the material, bearing witness to the uncertainty of the future or existential threat, and resisting and destabilizing the patriarchal and militaristic mechanism of war. The diary as a genre of writing about life needs to be intersectionally disassembled and studied from the trans-national standpoint, in the context of the topic and the act of writing. The diary is determined not only by the historical context from which it originates, but also by the cultural matrix and opposing stereotypes that find their basis in writing about sex and gender in the text. Although the genre is primarily associated with a woman’s act of writing in the privacy of her home, together with the fact that many more women than men were active in this genre, it is still the case that men tend to take over in the genre-forcing the image of the soldier as a social paradigm. Despite the generally accepted limitations in the study of women authors overall, it is crucial to construct a different theoretical framework based on the consciousness of the gender designation of the author, the study of the dualities of private and public, the personal and the political, the individual and the collective and the social and the cultural; the position that censorship takes and the marginalization of female experience, the analysis of discourse and points where a particular self is imprinted into the body of text. A woman’s self, just like her identity, is a category that not only defines the text of the diary, but the author’s position as well, which adds up to the practice of the destabilization of the traditional norm of the genre and its features. These categories define the role of a woman in literature, her affirmation in the articulation of her creativity and her alternative knowledge, which are a staple for social transformation.
Closed Spaces of Nation, Gender and Depression in Janice Galloway’s The Trick Is To Keep Breathing
Authors: Mulalić Lejla
Published: February 2023

The eruption of discourses of devolution and independence in Scotland since the late 1970s has called for an equally passionate discussion and mapping of the Scottish novel as a vibrant representation of an emerging nation. However, when applied uniformly, this approach results in a rather homogeneous concept of Scottishness, thus clearly denying the possibility of individual literary voices. The last section of the paper discusses Galloway’s views on national identity and her own writing. Looking at her interviews and articles over a longer period, we witness a process of self-fashioning and a genuine search for her own identity in the midst of the clichés of Scottishness, the forced dichotomies of Anglo-Scottish incompatibility, condescending and oversimplifying readings of her fiction, as well as her deep commitment to exploring the lives of women. All of these are powerfully silenced by Galloway’s authentic voice as she refuses the labels of nationalism and feminism, considering them equally limiting. Looking towards the diversity of European cultural influences rather than looking forever inwards in search of an imagined national past and imagined community, she embodies a new, open and ever-changing Scottishness. Most importantly, she does not lose her way in the ethereal heights of the national question and literature. That is why she invokes both the necessity and scarcity of love in our lives, while subtly reminding us to keep breathing, and maybe even consider learning to swim.
São Martinho de Dume: entre conselhos ou preceitos morais como preocupação prática
Authors: Silva Praseres Janilce
Published: February 2023

A reflexão a seguir centra-se na leitura e interpretação opúsculo moral intitulado Regra da Vida Virtuosa, de São Martinho de Dume. Nesse sentido, apresentamos as quatro virtudes cardeais como uma reflexão moral, pois trata-se de dar conselhos que visam uma preocupação sobre a ação prática, apontamos, ainda que São Martinho, no século VI, marcou o início da cultura portuguesa.
Kant's dynamic metaphysics: kant's theory of judgment and the nature of the theoretical knowledge of consistency in empirical reasoning
Authors: Vollet Lucas
Published: February 2023

Kant's theory of judgment involves his answer to the question "How is knowledge of the pattern underlying intentional strategies of objective - true and justified - representation of empirical events possible?" When we problematize this question, the problem of the scope of our notion of consistency in empirical reasoning emerges. We will argue in this article that Kant's theory includes a thesis about the circular nature of our patterns of consistency, based on the ability to protect the conceptual presuppositions that harmonize knowledge of truth as opposed to falsity in any paradigm of theoretical reflection. This thesis allows Kant to develop a foundationalism about the knowledge of the content of judgments (the ability to recognize conceptual correctness or rule consistency) without committing to a static and transcendent view of the ideal object of our assertion strategies. In our view, this view is still one of the most competitive in describing the necessary - though not static - status of the propositions of empirical science.