bluuebunny/crossref_metadata_2025 huggingface dataset:
Flor Brilhante e as cicatrizes da pedra
Authors: Rainho Jade
Published: September 2021

No texto, nos é revelada uma cruel distinção: enquanto no mundo dos “brancos” deixar a terra, migrar, refugiar-se, despatriar-se é, muitas vezes, solução para a manutenção da vida, para os Guarani Kaiowá esta não é uma alternativa possível; deixar a terra significa o abandono de seu próprio corpo e vitalidade ancestral – é como seguir vazio, desenraizado, portanto, sempremorto. Para além disso, há também a percepção explícita de que, para eles, se viver já é difícil de posse da terra nesse cenário de profundas mazelas e violações de direitos básicos, viver sem um pedaço de chão de onde se possa tirar o sustento é dar início à contagem regressiva da morte sentenciada, sucessiva e inevitável, que leva um a um no atravessamento do tempo.
Max Schmidt en el Mato Grosso
Authors: Bossert Federico , Villar Diego
Published: September 2021

Entre 1899 e 1929, Max Schmidt trabalhou no Museu Etnológico de Berlim e realizou três expedições ao Mato Grosso para continuar as investigações de seu mentor Karl von der Steinen. Entre 1900 e 1901, ele explorou o alto Xingu tentando alcançar o território Kamaiurá, encontrando vários índios Bacairí, Nahukuá e Aweti, e também os Guató dos pântanos do alto Paraguai. Em 1910, ele participou do Congresso Internacional de Americanistas em Buenos Aires e aproveitou a oportunidade para estudar os Paresí. Entre 1926 e 1928, empreendeu uma viagem final ao alto Xingu e visitou Bacairí, Kaiabi, Paresí, Iranches e Umotinas. Nessas viagens, Schmidt tirou dezenas de fotos que documentam a vida indígena e os primeiros contatos interétnicos. O artigo apresenta o contexto etnográfico dessas imagens, discutindo os incidentes de cada jornada, relatados em diários de viagem detalhados; a exploração e conquista do Mato Grosso indígena por agentes do Estado e barões da borracha; a herança etnográfica e metodológica de Adolf Bastian, Karl von der Steinen e a discussão em andamento na etnologia alemã e os próprios interesses teóricos e museográficos de Schmidt. Finalmente, discute o trabalho de campo etnográfico de Schmidt e o papel que a fotografia teve nele.
Penggunaan Ruang Publik Sebagai Tempat Berjualan Pedagang Pasar Tungging Cempaka Raya Kelurahan Telaga Biru Kota Banjarmasin
Authors: Sigit Ruswinarsih ,Rahmat Nur Muhammad Faisal
Published: September 2021

Bagi pedagang pasar tungging Jalan Cempaka Raya, jalan sebagai ruang publik yang berfungsi sebagai ruang ekonomi yang dimiliki oleh berbagai individu yang terlibat didalamnya. Selain itu ruang publik memungkinkan interaksi. Penelitian ini bertujuan untuk mengetahui: (1) Fungsi pasar tungging sebagai ruang publik bagi pedagang pasar tungging (2) Upaya aktor pasar tungging dalam menjaga eksistensi pasar tungging. Metode penelitian menggunakan metode kualitatif. Sumber data yang ditetapkan yaitu dengan purposive sampling dengan pedagang yang sudah lama berjualan di pasar tungging Jalan Cempaka Raya. Pengumpulan data dilakukan dengan teknik wawancara, observasi, dan dokumentasi. Analisis data hasil penelitian ini menggunakan reduksi data, penyajian data dan verifikasi. Hasil penelitian menunjukan bahwa: (1) fungsi pasar tungging sebagai ruang publik adalah sebagai ruang yang menampung aktivitas berjualan pedagang pasar tungging. Sebagai sumber matapencaharian bagi pedagang pasar tungging. Serta pasar tungging berfungsi sebagai tempat terjadinya interaksi sosial. (2) Upaya aktor pasar tungging dalam menjaga eksistensi pasar tungging adalah dengan membayar uang keamanan. Menjaga keamanan dan kebersihan  Menjalin hubungan baik antara pedagang dan pengelola pasar
Дослідження якості відтворення штрихових зображень трафаретним друком на тканинах
Authors: Чепурна Катерина Олександрівна , Хмілярчук Ольга Іларіонівна , Колчина Катерина Олександрівна
Published: September 2021

В роботі наведено результати дослідження впливу технологічних параметрів трафаретного друку на якість відтворення штрихової інформації; проаналізовано вплив фактури та товщини волокна тканини на графічну точність відтворення штрихових зображень та рівномірність плашок. Встановлено, що для фактур тканин, які мають певний напрямок волокон і виражений рисунок поверхні, напрямок друку вздовж або впоперек напряму волокон має значення; товщина волокна тканини також впливає на величину розтискування, але в комплексі з видом переплетення та щільність за ступенем заповнення нитками. Виявлено загальну тенденцію до зменшення величини розтискування, за умови, що тканина має мінімально виражену фактуру і є помірно щільною. За результатами аналізу проведених досліджень сформульовано рекомендації щодо трафаретного друку на тканинах.
Формування зношеності пластикових карток
Authors: Киричок Тетяна Юріївна , Назаренко Олена , Бараускєне Оксана Іванівна
Published: September 2021

Використання, і, відповідно, виробництво пластикових карток, незважаючи на зростання частки електронних платежів та платежів з використанням мобільних пристроїв, постійно зростає. Разом з тим підвищуються вимоги до їх якості, в тому числі до зносостійкості. Для розроблення технологічних процесів виготовлення якісних, зносостійких карток необхідно застосовувати процеси штучного зношування, які б в свою чергу ураховували максимальну кількість факторів, явищ та процесів, що відбуваються з різними типами карток протягом їх життєвого циклу.
Застосувавши підходи, описані нами раніше стосовно інших поліграфічних виробів, можемо запропонувати термінологію для використання процесів забезпечення зносостійкості пластикових карток.
З урахуванням переважної більшості зазначених факторів зношування та видів впливу на картку необхідно застосовувати удосконалення виробничих процесів і забезпечення нормативного терміну служби картки.
Під час використання карток у реальному обігу, звісно, на них діють суттєво складніші сполучення факторів впливу, ніж ті, які моделюються в лабораторних умовах. Тому довговічність карток та пластикових документів не може бути точно встановлена в лабораторних умовах, де відбувається прискорене тестування, результати якого екстраполюються лише для прогнозування ефективності функціонування протягом багатьох років.
Врахувавши описані у нашому дослідженні фактори та впливи на картки, можливо удосконалити процеси штучного зношування карток задля цілеспрямованого удосконалення і зменшення ризиків та чинників електромагнітного впливу на картку у звичайному житті.
Cluster analysis for multidimensional objects in fuzzy data conditions
Authors: Zack Yuriy
Published: September 2021

This article presents many different areas of practical applications of multivariate cluster analysis under conditions of fuzzy initial data that are described in the literature. New algorithms and formula expressions are proposed for combining various multi-dimensional objects, the parameters of which are given by fuzzy-sets, into clusters along with calculating the coordinates of the centroids of their membership functions. Various types of clustering criteria are formulated in the form of minimizing the weighted average and the sum of distances between the centroids of objects and clusters presented in different metrics, as well as maximizing the distances between the centroids of different clusters. The formulations and mathematical models of three different NP-hard problems of multidimensional clustering in fuzzy-data conditions are proposed; while solving them any of the considered optimality criteria can be used. Heuristic algorithms for the approximate solution of two formulated problems have been developed. The algorithm for solving the 1st problem is illustrated with a numerical example. The obtained results can serve as a direction for further research and have wide practical applications.
Developing an algorithm for rapid assessment of living standards and quality of life of the population in the region
Authors: Lesnichaya Marina , Kolchina Oksana , Pahomov Evgenii
Published: September 2021

The article presents the rapid assessment methodology that allows analysts to carry out qualitative monitoring of the living standards of the population using a wide range of methods for statistics processing (factor analysis, cluster analysis, discriminant analysis, method of combining indicators of different dimensions). This methodology is characterized by the high speed of mathematical calculations, availability to users with different skill levels and universal applicability to various study objects. The rapid assessment method is intended for screening the living standards of the population and activity quality of the territorial authorities, taking into account a different set of indicators. This article offers the author’s indicator system for assessing the living standards and quality of life of the population. The methodology algorithm describes flowcharts of the index method for combining statistical observations of different dimensions, which make it possible to automate the process of territory ranking. The study covers 12 urban districts and 43 municipal districts of Rostov Oblast. The methodology described in the article will help eliminate a subjective factor while monitoring, rationally distribute financial resources allocated annually by the authorities to support programs for socio-economic development of the territory, increase the economic efficiency and implementation speed of innovative projects that have a direct impact on the living standards and quality of life of the population.
An Assessment of Storm Surge Risk in Coastal Communities in the Rio Grande Valley
Authors: Kyne Dean
Published: September 2021

(1) Background: Cameron County, which is located in the Rio Grande Valley, holds historical records for storm surges with noticeable property damage, fatalities, and injuries; (2) Methods: using storm surge hazard datasets from the National Oceanic and Atlantic Agency (NOAA), and American Community Survey (ACS) 2019 datasets and Geographic Information System (GIS), the study estimates at-risk population and their socio-demographic attributes; (4) Conclusions: Estimated water levels of a storm surge could be reached up to 5 feet in category 1 event, 9 feet in category 2, 17 feet in category 3, and above 20 feet in category 4 and 5. In the category 5 event, there is an estimated 37% (159,659) of the total county’s population (434,294) will be under flooded water. Suggestions are made to better prepare and successfully evaluate.
Changes in Alienation in Physical Education Classes, School Happiness, and Future Healthy Life Expectancy After the COVID-19 Pandemic in Korean Adolescents
Authors: Lee Seung-Man , Yoo Jung-In , Youn Hyun-Su
Published: September 2021

This study aims to investigate the changes in the structural relationship between alienation in physical education (PE) class, school happiness, and future healthy life expectancy in Korean adolescents after the COVID-19 pandemic. The data were collected from adolescents in the Republic of Korea using scales for these factors. The collected data were analyzed with frequency analysis, reliability analysis, validity analysis, independent t-test, and path analysis. The key results were as follows. First, there were partial changes in each of the parameters since the outbreak of COVID-19. Second, before the pandemic, alienation in PE class negatively affected school happiness, and school happiness positively affected future healthy life expectancy; however, alienation in PE class did not affect future healthy life expectancy showing a complete mediating effect. Third, during the pandemic, alienation in PE class negatively affected school happiness, and school happiness positively affected future healthy life expectancy; alienation in PE class negatively affected future healthy life expectancy, showing a partial mediating effect. These findings emphasize the importance and potential of school education, especially PE, in promoting happiness and healthy life in adolescents. We expect these findings to have practical implications for future research by presenting theoretical and empirical data.
Comparative Assessment of the Activity of Decoquinate and Its Quinoline-O-Carbamate Derivatives against Toxoplasma gondii in vitro and in Pregnant Mice Infected with T. gondii Oocysts
Authors: Ramseier Jessica , Imhof Dennis , Anghel Nicoleta , Hänggeli Kai , Betteck Richard , Balmer Vreni , Ortega-Mora Luis-Miguel , Sánchez-Sánchez Roberto , Ferre Ignacio , Haynes Richard K , Hemphill Andrew
Published: September 2021

The quinolone decoquinate (DCQ) is widely used in veterinary practice for the treatment of bacte-rial and parasitic infections, most notably coccidiosis in poultry and in ruminants. We have in-vestigated the effects of treatment of Toxoplasma gondii in infected human foreskin fibroblasts (HFF) with DCQ. It induced distinct alterations in the parasite mitochondrion within 24h, which persisted even after long-term (500 nM, 52 days) treatment, although there was no parasiticidal effect. Based on the low half-maximal effective concentration (IC50) of 1.1 nM and the high selec-tivity index of >5000, the efficacy of oral treatment of pregnant mice experimentally infected with T. gondii oocysts with DCQ at 10 mg/kg/day for 5 days was assessed. However, the treatment had detrimental effects, induced higher neonatal mortality than T. gondii infection alone, and did not prevent vertical transmission. Thus, three quinoline-O-carbamate derivatives of DCQ antici-pated to have better physicochemical properties than DCQ were assessed in vitro. One such com-pound RMB060 displayed an exceedingly low IC50 of 0.07 nM when applied concomitantly with infection of host cells and had no impact on HFF viability at 10 µM. As was the case for DCQ, RMB060 treatment resulted in alteration of the mitochondrial matrix and loss of cristae, but the changes became apparent at just 6h after commencement of treatment. After 48h, RMB060 induced the expression of the bradyzoite antigen BAG1, but TEM did not reveal any other features remi-niscent of bradyzoites. Exposure of infected cultures to 300 nM RMB060 for 52 days did not re-sult in complete killing of all tachyzoites, although mitochondria remained ultrastructurally damaged and there was a slower proliferation rate. Treatment of mice infected with T. gondii oocysts with RMB060 did reduce parasite burden in non-pregnant mice and dams, but vertical transmission to pups could not be prevented.
Associated Words Explorer (AWE) user manual
Authors: Church Joshua , Walker LaKenya , Bednar Amy
Published: September 2021

This manual is intended for new users with minimal or no experience with using the Associated Word Explorer (AWE) tool. The goal of this document is to give an overview of the main functions of AWE. The primary focus of this document is to demonstrate functionality. Every effort has been made to ensure this document is an accurate representation of the functionality of the AWE tool. For additional information about this manual, contact ERDC.JAIC@erdc.dren.mil.
Inserting a Drainage Strip into the Pre-tracheal Space to Treat Tension Pneumomediastinum: A Case-control Study
Authors: Liu Qianli , Li Xiaohui , Han Zhengzheng , Hong Chun
Published: September 2021

Background: Pneumomediastinum is an emergency pediatric disease. A severe tension pneumomediastinum can result in respiratory and circulatory dysfunction. However, few papers describe surgical methods to treat tension pneumomediastinum in a normative manner.Methods: We did a case-control study of 104 pediatric patients with tension pneumomediastinum and comorbid type II respiratory failure. Fifty-two patients were treated with a drainage strip being inserted into the pre-tracheal space while other 52 patients were treated without drainage. Arterial blood pO2 and pCO2 after 30 minutes and 12 hours of mechanical ventilation, chest radiography results after 12 hours of mechanical ventilation, and the length of stay in PICU of the two groups were analyzed by paired t-tests and Chi-square.Results: Chest radiography after 12 hours of mechanical ventilation showed that the pneumomediastinum basically disappeared in the surgery group but did not decrease significantly in the control group. The arterial blood pCO2 after 12 hours of mechanical ventilation and the length of stay in PICU were significantly lower in the surgery group than in the control group (p<0.001, p<0.001), while the arterial blood pO2 after 12 hours of mechanical ventilation was significantly higher in the surgery group than in the control group (p<0.001). There were no significant intergroup differences in other variables. No recurrence occurred in either group during 7–14 days after discharge, and all patients recovered.Conclusions: Our method for draining tension pneumomediastinum improved respiratory function and shortened the length of stay in PICU.Trial registration: ChiCTR2000039496. Date of registration: 2021/2/25 (retrospectively registered).
Preventive effect of cryotherapy on persistent chemotherapy-induced peripheral neuropathy after completion of weekly paclitaxel therapy for breast cancer
Authors: Shigematsu Hideo , Kimura Yuri , Itagaki Tomoko , Yasui Daisuke
Published: September 2021

BackgroundChemotherapy-induced peripheral neuropathy (CIPN) is an important adverse event of taxane-based chemotherapy, which can persist in a substantial proportion of patients for years. Cryotherapy therapy is shown to be effective in prevention of CIPN during chemotherapy, but its protective effect on persistent CIPN has not been reported. MethodsThis observational study was performed as an ancillary analysis of a randomized trial investigating the preventive effect of cryotherapy on weekly paclitaxel-induced CIPN in breast cancer patients (UMIN000034966). Eligible cases were evaluated for Functional Assessment of Cancer Therapy-Neurotoxicity (FACT-NTX) score and Patient Neurotoxicity Questionnaire (PNQ) at more than one year after completion of weekly paclitaxel. ResultsThirty-eight cases were evaluated for persistent CIPN with a median 2.3 (1.3-3.1) years after completion of weekly paclitaxel. The incidence of a significant decrease in FACT-NTX scores was numerically lower in the cryotherapy group compared with the control group (15.8% vs. 36.8%, p = 0.13). There was also a lower grade of PNQ sensory (p = 0.02) and motor (p = 0.17) in the cryotherapy group compared with the control group. ConclusionIn breast cancer patients treated with weekly paclitaxel, cryotherapy resulted in a numerical decrease in the incidence of persistent CIPN after completion of weekly paclitaxel therapy.
The Selah Study Protocol of Three Interventions to Manage Stress among Clergy: A Preference-based Randomized Waitlist-control Trial
Authors: Tice Logan C , Eagle David E. , Rash Joshua A. , Larkins Jessie S. , Labrecque Sofia M. , Platt Alyssa , Yao Jia , Proeschold-Bell Rae Jean
Published: September 2021

Introduction: Like many helping professionals in emotional labor occupations, clergy experience high rates of mental and physical comorbidities. Regular stress management practices may reduce stress-related symptoms and morbidity, but more research is needed into what practices can be reliably included in busy lifestyles, and practiced at a high enough level to meaningfully reduce stress symptoms. Methods and analysis: The overall design is a preference-based randomized waitlist-control trial. United Methodist clergy in North Carolina will be eligible to participate. The intervention and waitlist-control groups will be recruited by email. The interventions offered are specifically targeted to clergy preference and include: Mindfulness-Based Stress Reduction, Daily Examen and stress inoculation training. Surveys will be conducted at 0, 12 and 24 weeks with heart rate data collected at 0 and 12 weeks. The primary outcomes for this study are self-reported symptoms of stress and heart rate at week 12 for each intervention compared to waitlist control; the secondary outcome is symptoms of anxiety comparing each intervention vs waitlist control. Ethics and dissemination: Ethical approval was obtained from the Duke University Campus IRB (2019-0238). Results will be made available to researchers, funders, and members of the clergy community.ClinicalTrials.gov trial registration number: NCT04625777.
Hospital Readmission in Patients With COVID-19
Authors: Rahimian Neda , Heidari Mahshid , Hashemi-Madani Nahid , Tavakoli Nader , Khamseh Moammad E
Published: September 2021

Objective: During the COVID-19 pandemic, the demand for hospital beds has exceeded substantially. Thus, we aimed to conduct this study to identify factors associated with the risk of readmission in order to introduce the best discharge plan for patients with high risk of hospital readmission. Method: This is a multicenter, case-control study included 1357 patients hospitalized with COVID-19 infection. Age-sex-matched case and control groups were paired at 1:2 ratios. COVID-19 readmission rate was assessed. Moreover, Logistic regression analysis was applied to determine the factors associated with readmission. Results: Of the 1357 patients, 99 (7.29%) subjects were readmitted. The most common cause of readmission was respiratory distress. The median (IQR) of the interval between hospital discharge and the second admission was 5 (2-16) days. Upon adjusting with the main risk factors, having at least one underlying disease and being treated with the corticosteroid (GC) were significantly associated with a higher rate of readmission (OR: 2.76, 95% CI :1.30- 5.87) and (OR:8.24, 95% CI :3.72- 18.22), respectively.Conclusion: Identification of Risk factors of COVID 19 readmission will improve resource utilization and patient care.
Higher Fruits and Vegetables and Less Red Meat Intake Lower Precocious Puberty Risk
Authors: Gu Qiuyun , Wu Youmei , Feng Zhuowei , Chai Yimeng , Hou Shan , Yu Zhiping , Shen Xiuhua
Published: September 2021

Background & aims: The role of dietary intake on precocious puberty remains unclear. This study aimed to investigate the association between the amount and frequency of dietary intake and the risk of precocious puberty in Chinese girls. Methods: In this case-control study, we enrolled 185 precocious puberty girls and 185 age-matched controls.Their dietary intake was assessed through a semi-quantitative food frequency questionnaire. Their sociodemographic and lifestyle data were collected. The associations between dietary intake and risk of precocious puberty were assessed by conditional logistic regression models. Results: Despite a higher weight and height of girls in the case group than in the control group, there was no statistical difference in BMI between the two groups (P=0.077). After multivariate adjustment, consuming higher amount of red meat was associated with higher precocious puberty risk [≥50g/day vs. <25g/day: OR (95% CI) = 2.74 (1.25, 6.02), P = 0.0121]. Compared with fruit intake frequency <7 times/week, consuming higher frequency of fruit was associated with lower precocious puberty risk [7-10 times/week: OR (95%CI) = 0.36 (0.14, 0.91); ≥10 times/week: OR (95%CI)= 0.21 (0.05, 0.94); P for trend = 0.024]. Furthermore, compared with vegetables intake <112.5 g/day, higher amount of vegetables intake was associated with lower risk of precocious puberty [112.5-240g/day: OR (95%CI) = 0.31 (0.12, 0.77); ≥240.0g/day: OR (95%CI) = 0.25 (0.11, 0.59); P for trend = 0.002]. Conclusion: Consuming more fruits and vegetables and less red meat could potentially reduce the risk of precocious puberty in Chinese girls.
Experimental Study On The Root-Soil Friction Mechanical of Typical Grasses With Soil Moisture In Purple Soil Bunds
Authors: Gan Fengling , Wei Jie , Li Shasha
Published: September 2021

[Aims] Bunds composed of plants with strong root systems have become one of the most important soil conservation measures for controlling soil erosion on sloping farmlands in the Three Gorges Reservoir area. In order to measure the friction characteristics of the root-soil interfaces to screen grasses for use in bunds to provide optimal soil bund protection. [Methods] The influences of interface, soil moisture and vertical load were examined by using direct shear friction and pull-out friction tests in the study. [Results] The results support the following conclusions. i) Friction characteristics were lower at interfaces in bulk soils than at root-soil interfaces. Direct friction characteristics were higher at the root-soil interface for goosegrass than other plants tested in this study. ii) The roots of grasses can substantially improve the soil shear strength under conditions of low (5%) and high soil moisture (25%). The relationships between friction characteristics and soil moisture can be described by binomial functions. iii) The constitutive relationship between the shear strength at the root-soil interface and vertical load can be described by a hyperbolic model that satisfies the Mohr-Coulomb criterion. The maximum pulling resistance was in the following order: goosegrass > barnyard grass > crabgrass. [Conclusions] Among the three grasses tested, the goosegrass root system has a highest resistance to deformation capability for soil conservation. These results can be used as references for understanding and controlling the friction characteristics and collapse of soil bunds in the Three Gorges Reservoir area.
The Analysis of Corneal Asphericity and its Related Factors in Cataract Patients
Authors: Li Chen , Lu Peirong
Published: September 2021

Purpose: To determine the corneal asphericity and its related factors in cataract patients.Methods: This study enrolled 121 eligible eyes of 121 cataract patients. The corneal Q values of anterior and posterior surface were measured in the central 3.0, 4.0, 5.0, and 6.0 mm zone using the Sirius System. Age, gender, and corneal higher-order aberrations (HOAs) were recorded. Comparison of preoperative and postoperative Q value was conducted in 103 eyes of 103 patients three months after surgery.Results: The Q value of the anterior corneal surface at 6.0 mm zone and the posterior surface in 3.0, 4.0, 5.0, and 6.0 mm zone were statistically significant across the different age groups. The Q value of the posterior surfaces in 3.0, 4.0, 5.0, and 6.0 mm zone was statistically significant between the male and the female groups. The Q values of the anterior corneal surface in the 6.0 mm zone were positively correlated with Z40 cornea, Z40 CF, Z33,-3 CF, and total corneal HOAs; While the Q value of the posterior surface in the 6.0 mm zone were negatively correlated with Z31,-1 cornea, Z33,-3 cornea, Z33,-3 CF, Z31,-1CB, Z40 CB, and total corneal HOAs. Besides, no significant change was found in corneal Q value 3 months after surgery.Conclusion: There were great individual differences between the corneal asphericity of the cataract patients. Age, sex, and HOAs seemed to be correlated with the corneal asphericity. The preoperative Q value can be used as one of the parameters for personalized selection of intraocular lens.
Toward Controllable Quantum Transports and Novel Magnetic States in Eu1–xSrxMnSb2
Authors: Zhang Qiang , Liu Jinyu , Cao Huibo , Phelan Adam , DiTusa John , Tennant David , Mao Zhiqiang
Published: September 2021

Magnetic semimetals carry a great promise for potential applications in novel spintronic devices. Nevertheless, it is a challenging topic to realize the tunable topological states by the magnetism in a controllable way. Here, we report novel magnetic states and a tunability of the topological semimetallic states via controlling the Eu spin reorientation in Eu1-xSrxMnSb2. Increasing the Sr concentration in this system induces a surprising reorientation of noncollinear Eu spins to the Mn moment’s direction and an appearance of topological semimetallic behavior. The Eu spin reorientations to distinct collinear antiferromagnetic orders are also driven by the temperature/magnetic field, which are coupled to transport properties of the relativistic fermions generated the 2D Sb layers. These results suggest nonmagnetic element doping to the rare-earth element site may be an effective strategy to generate topological electronic states and new magnetic states in layered compounds involving spatially separated rare-earth and transition metal layers.
Dietary Supplementation of Inulin On Glycolipid Metabolism in Gestational Diabetes Mellitus via RENT/AKT/IRS Pathway
Authors: Miao Miao , Dai Yongmei , Rui Can , Fan Yuru , Wang Xinyan , Fan Chong , Mu Juan , Hou Wenwen , Dong Zhiyong , Li Ping , Sun Guiju , Zeng Xin
Published: September 2021

Background: Gestational diabetes mellitus (GDM) has significant short and long-term health consequences for both the mother and child. There is limited but suggestive evidence that inulin could improve glucose tolerance during pregnancy. This study assessed the effect of inulin on glucose homeostasis and elucidated the molecular mechanisms underlying the inulin-induced antidiabetic effects during pregnancy. Method: Female C57BL/6 mice were randomized to receive either no treatment, high-dose inulin and low-dose inulin for 7 weeks with measurement of biochemical profiles. A real-time2 (RT2) profiler polymerase chain reaction (PCR) array involved in glycolipid metabolism was measured. Results: Inulin treatment facilitated glucose homeostasis in a dose-dependent manner by decreasing fasting blood glucose and total cholesterol, and improving glucose tolerance. Suppressing resistin (RETN) expression was observed in the inulin treatment group and the expression was significantly correlated with fasting blood glucose levels. The ratios of p-IRS to IRS and p-Akt to Akt in liver tissue and the ratio of p-Akt to Akt in adipose tissue increased significantly after inulin treatment. Conclusions: Our findings indicated the observed decreased glucose level may be due to insulin signaling pathway repairment due to decreased expression of RETN and enhanced phosphorylation of IRS and Akt in GDM mice.
Changes In Antioxidant Systems And Sucrose Metabolism In Maize Varieties Exposed To Cd
Authors: Li Cong , Cao Yingdi , Li Tianfeng , Guo Meiyu , Ma Xinglin , Zhu Yanshu , Fan Jinjuan
Published: September 2021

While it is generally accepted that different maize varieties respond in various ways to cadmium (Cd) stress, the physiological mechanisms that determine how they respond are not well-defined. We do know, however, that antioxidant systems and sucrose metabolism help plants to cope with abiotic stresses, including stress from Cd. Seed is sensitive to Cd stress during germination stage. In this study, we investigated how the antioxidant systems, sucrose metabolism, abscisic acid (ABA) and gibberellin (GA3) concentration in two maize varieties with low (FY9) or high (SY33) sensitivities to Cd changed when Cd was added at 20 mg L−1 over different germination stages (3, 6, and 9 days). As Cd accumulated, the germination rate decreased, and growth was inhibited. The O2•-, malondialdehyde (MDA), and proline (Pro) concentrations, and the superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), and lipoxygenase (LOX) activities increased compared to the CK (without Cd). The expression levels of three genes (ZmOPR2, ZmOPR5 and ZmPP2C6) that respond to oxidative stress increased differently in two varieties under Cd stress. The activity of the antioxidant system including the transcript levels of oxidative stress response genes were higher in Cd-tolerant variety, FY9, than in sensitive variety, SY33. And then, we also examined sucrose metabolism levels that were increased compared to the CK. However, it was more active in the Cd-sensitive variety, SY33. Therefore, these results also suggest that antioxidant systems are first respond to Cd stress in maize plants, and sucrose metabolism is cooperation and complement that are exposed to Cd.
Effect of Retained Placenta And Clinical Mastitis On Reproduction Parameters, Immune Response And Steroidogenic Receptors Gene Expression In Postpartum Crossbred Crossbreed Dairy Cows
Authors: Ramos Oglênia , Rezende Amanda , Alvarenga Paula , Campos Carla , Rezende Estevão , Silva Marcelo , Carneiro Luisa Cunha , Moraes Giovanna , Saut João Paulo , Santos Ricarda
Published: September 2021

The purpose of this study was to evaluate the effect of retained placenta (RP) and clinical mastitis (CM) on the reproductive efficiency of crossbred dairy cows during the postpartum period and to investigate the effect of them in some innate immune system indicators. For this, in the first experiment a total of 232 crossbred dairy cows were evaluated and divided into three groups as: healthy control, RP and CM. The incidence of RP and CM was evaluated after parturition until 30 days postpartum (DPP) and reproductive rates were measured. In experiment 2, 30 crossbred dairy cows were divided into three groups as in Experiment 1. Between 40 and 50 DPP, clinical, gynecological examination and endometrial cytobrush were performed to evaluate subclinical endometritis and gene expression of interleukin- 1β (IL-1β), interleukin-6 (IL-6), chemokine ligand -5 (CCL5), estrogen α (ESR1) and progesterone (PGR) receptors by qRT-PCR analysis. In Experiment 1, the conception rate at 1st AI was lower in RP and CM groups and pregnancy rate at 150 days decreased in cows with CM. Calving-to-1st AI interval and days open were shorter in healthy cows. In Experiment 2 the occurrence of subclinical endometritis was 26.7% and was higher in cows with RP and CM. The expression of IL-1β was increased in RP and CM groups, while IL-6 was less expressed in RP group. The chemokine CCL5, ESR1 and PGR were similar between groups. In conclusion, cows with RP and CM had their reproductive efficiency negatively affected and had they initial pro-inflammatory response improved by the increase of IL-β, while, IL-6 was lower in animals with RP probably because it was evaluated later in the postpartum.
Describing The Use of Two Hybrid Prostheses in The Staged Surgical Repair of Aortic Dissection
Authors: Pathare Presheet , Tandler René , Weyand Michael , Harig Frank
Published: September 2021

Background-Reconstruction of the thoracoabdominal aorta after dissection (Stanford Type A with extension into descending aorta) has limited surgical options. Described here is a novel technique for the staged surgical repair of the thoracoabdominal aorta after reconstruction of the ascending aorta with aortic arch using a hybrid prosthesis. Case presentation- The thoracoabdominal aorta is accessed via a lateral thoracotomy. After a left-left bypass to perfuse the descending aorta, the proximal end of the prosthesis is anastomosed to the proximal aorta and distal end of the new prosthesis is then inserted into the true lumen of the descending aorta and the stent is deployed. ﻿Conclusion-Using this technique, operative time is reduced with accurate reconstructions of the anatomy.
Lonely, Harassed And Abandoned In Society: The Lived Experiences of Iranian Homeless Youth
Authors: Johari Fatemeh , Iranpour Abedin , Dehghan Mahlagha , Alizadeh Somayeh , Safizadeh Mansoure , Sharifi Hamid
Published: September 2021

Introduction: Homelessness is increasing among young adults in large cities. According to the United Nations, there are more than one bilion absolute or relative homeless people in the world. This study was conducted to explain the lived experiences of homeless youth in southeastern Iran.Materials and Methods: This study was conducted with a conventional qualitative content analysis in Kerman, southeastern Iran, in 2020. The participant was young homeless adults aged 18-29 years, who were using homeless shelters provided by municipality, sleeping in parks or on streets. Data were collected through 13 in-depth and semi-structured interviews and three focus group discussions. Data were analyzed by Granheim and Lundman’s qualitative content analysis.Results: The main category of “lonely, annoyed and abandoned in society” and three subcategories of Aversion to society, comprehensive harassment and lack of comprehensive support were extracted. The experiences of young homeless adults showed that they escaped from community due to addiction, feeling like a burden to others and social isolation, and not only have they been left without support in society, but they have also suffered from all kinds of physical and psychological harassments.Conclusion: The lived experiences of homeless people show that in addition to appropriate facilities and living conditions, they require respect, reduced social stigma, discrimination, and favorable conditions for return to life. Therefore, authorities should identify and settle their problems and needs.
Optical Stereometric Analysis of An Experimental Partially-Edentulous Mandible
Authors: Poštić Srđan , Milošević Miloš , Maneski Taško , Mladenović Goran , Brković Snežana , Trifković Branka
Published: September 2021

Background: Stereooptics method have been successfully used in biomechanical studies of models of dental and jaw bone tissues. The aim of this study was to investigate, by optical stereometry, the distribution of occlusal loads, depending on the functional deformities, on casts of a partially-edentulous lower jaw without copings as well as on the dedicated copings and the remaining solid tissue under the copings.Material and Methods: Precise measurement of strain and displacement of partially-edentulous mandibular control and experimental casts were provided by the digital image correlation method and software ARAMIS which determined the shape of the photographed object with high accuracy, its dimensions, field of three-dimensional (3D) movements, vector of distorted field and features of the biomaterial. Simulated loads were in the range between 0 and 1000 N.Results: Displacements and deformations of abutment teeth within the control cast of a partially-edentulous mandible were 0.48% for incisor without coping, 10.29% for canine without coping and 6.64% for premolar without coping, and within the experimental cast of a partially-edentulous mandible they were 0.29% for incisor with coping, 7.007% for canine with coping and 4.98% for premolar with coping.Conclusions: When loading the abutment teeth, the distribution of strain through the remaining tooth substance is specific and various, and abutment teeth covered by protective copings are more resistant to loads.
High Flow Nasal Cannula Oxygen In Non-Critical Care Units In Patients Infected With SARS-CoV-2 Who Are Not Suitable For Intensive Care Unit
Authors: Bouetard Laura , Vignes Dorothée , Braham Dorra , Sterpu Raluca , Damoisel Charles , Doucet-Populaire Florence , Guillet-Caruba Christelle , Mion Mathieu , Goujard Cécile , Abgrall Sophie
Published: September 2021

Background:High-flow nasal cannula (HFNC) is a recent respiratory support technique used for patients with hypoxemic respiratory failure; its use usually takes place in critical care wards. During the second wave of Covid-19, almost 400 000 people were hospitalized in France, and intensive care units were overwhelmed. For patients who did not meet criteria for admission to an intensive care unit because of their age or their medical background, we proposed HFNC in non-critical care unit instead of standard oxygen therapy to improve patient survival and comfort.Objectives: To describe characteristics and outcomes of patients infected with SARS-CoV-2 with HFNC in non-critical care wards between September 2020 and June 2021.Methods: This was a single-center, retrospective cohort study conducted between September and June 2021 in Clamart Hospital, France. Patients infected with SARS-CoV-2 confirmed, who were not suitable for intensive care unit escalation, and who were proposed HFNC because of respiratory failure were assessed.Results:Thirty-one patients with SARS-CoV-2 were included, median age 87.0 years (interquartile range (IQR), 82.0-91.0), 52% men. Nineteen (61%) patients were OMS score 0, i.e. no disability in daily-life activities. HNFC was started a median of 3 days (IQR, 1-5.5) after hospitalization. Overall, median duration of HNFC was 6 days (IQR, 4-10). Eleven patients (35.5%) survived and were discharged from hospital.Conclusions:Our experience of HFNC for patients with COVID-19 outside of a critical care environment because of their age and comorbidities is positive allowing survival of 35% of old patients not admitted to an intensive care unit. Trial registration:Not applicable
Recognizing Molecular Structural Features by Pattern Recognition Techniques
Authors: Lu Qing , Bian Wensheng
Published: September 2021

Recognition of molecular structural features is one of the most attractive fields in chemistry, especially when combining with machine learning techniques. Pattern recognition techniques are straightforward in recognizing graphic features, but little attention was given to recognize molecular structural features. In this work, we propose a new method taking advantage of pattern recognition techniques to analyze structural features and obtain novel chemical insights. Specifically, the cluster analysis is presented to recognize structural features, which provides an alternative to the most widely used root mean square deviation (RMSD) method and the recently proposed blob detection method. Based on this, the convex hull of the molecule is constructed. The convex hull of molecules is highly appealing in the sense that one can introduce established theorems and properties from other disciplines into chemistry. Novel molecular descriptors based on convex hulls can be defined and show encouraging results, especially in providing new insights in understanding non-covalent interactions, adsorption processes, etc.
Surface Functionalization of Graphene Oxide with Hyperbranched Polyamide-Amine and Microcrystalline Cellulose for Efficient Adsorption of Heavy Metal Ions
Authors: Liu Zhihang , Wang Qian , Huang Xiujie , Li Jian
Published: September 2021

Graphene oxide (GO)-based adsorbents have received attention in the removal of heavy metal ions in wastewater due to its large specific surface area and oxygen-containing functional groups, which can enhance the interaction between GO and heavy metal ions. Many researchers are seeking economical and effective strategies to further improve the adsorption capacity of GO. Different from other studies, this study proposed to introduce more active groups with hyperbranched polymer and construct micro/nano 3D bumps with cellulose on the surface of GO to improve the adsorption performance of GO. First, hyperbranched polyamide-amine (HPAMAM) functionalised GO was fabricated by the formation of amide bond between the carboxyl group of GO and the amino group of HPAMAM to endow GO more active groups and increase the affinity of adsorbent with heavy metal ions. Then, dialdehyde cellulose (DAC) obtained through the oxidation of microcrystalline cellulose was grafted onto GO/HPAMAM by forming a Schiff-based structure between the amino group of HPAMAM and aldehyde group of DAC; it is used to fabricate micro/nano 3D bumps on the surface of GO to increase the contact area between the adsorbent and pollutants. The obtained GO/HPAMAM/DAC adsorbent exhibited strong adsorption capacity and good cycle stability for heavy metal ions. The maximum adsorption capacities of Pb(Ⅱ), Cd(Ⅱ) and Cu(Ⅱ) were 680.3, 418.4 and 280.1 mg/g at 298 K, which were better than those of most adsorbents reported. Pseudo-second-order kinetic model and Langmuir isotherm model could describe this adsorption process. The adsorption of Pb(Ⅱ), Cd(Ⅱ) and Cu(Ⅱ) contributed to the chelation or complexation of nitrogen- and oxygen-containing groups on GO/HAPAMAM/DAC adsorbent. This study may provide a novel strategy for improving the adsorption performance of GO with hyperbranched polymer and cellulose.
Artificial Intelligent Stenosis Diagnosis in Coronary CTA: Effect on the Performance and Consistency of Readers with Less Cardiovascular Experience
Authors: Han Xianjun , Luo Nan , Xu Lixue , Cao Jiaxin , Guo Ning , He Yi , Hong Min , Jia Xibin , Wang Zhenchang , Yang Zhenghan
Published: September 2021

Background: To investigate the influence of artificial intelligent (AI) based on deep learning on the diagnostic performance and consistency of inexperienced cardiovascular radiologists.Methods: We enrolled 196 patents who had undergone both CCTA and invasive coronary angiography (ICA) within 6 months. Four readers with less cardiovascular experience (Reader 1 to Reader 4) and two cardiovascular radiologists (level II, Reader 5 and Reader 6) evaluated all images for ≥50% coronary artery stenosis, with ICA as the gold standard. Reader 3 and Reader 4 interpreted with aid from an AI system, and the other four readers interpreted without the AI system. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy (area under the receiver operating characteristic curve (AUC)) of six readers were calculated at the patient and vessel levels. Additionally, we evaluated interobserver consistency between Reader 1 and Reader 2, Reader 3 and Reader 4, and Reader 5 and Reader 6.Results: The AI system had 94% and 78% sensitivity at the patient and vessel levels, respectively, which were higher than Reader 5 and Reader 6. Reader 3 and Reader 4 aided by AI had a higher sensitivity (range: +7.2%~ +16.6% and +5.9%~ +16.1%, respectively) and NPV (range: +3.7%~ +13.4% and +2.7%~ +4.2%, respectively) than Reader 1 and Reader 2 without AI. There was good interobserver consistency between Reader 3 and Reader 4 in interpreting ≥50% stenosis (Kappa value= 0.75 and 0.80 at the patient and vessel levels, respectively). Only Reader 1 and Reader 2 had poor consistency (Kappa value= 0.25 and 0.37). Reader 5 and Reader 6 had moderate agreement (Kappa value= 0.55 and 0.61).Conclusions: Our study showed that using AI could effectively increase the sensitivity of inexperienced readers and significantly improve consistency in diagnosing coronary stenosis via CCTA.Trial registration: The clinical trial registration number: ChiCTR1900021867Name of registry: Diagnostic performance of artificial intelligence assisted coronary computed tomography angiography for the assessment of coronary atherosclerotic stenosis
New treatment regimen for acute megakaryoblastic leukemia with BCR-ABL positive: case report and literature review
Authors: Shen Huafei , Shi Yuanfei , Zheng Xiaolong , Jin Jie , Xie Wanzhuo
Published: September 2021

Acute megakaryocytic leukemia (AMKL) is a rare type of acute myeloid leukemia (AML), which is characterized by its effect on megakaryocytes in bone marrow. Despite standard doses of anthracycline plus cytarabine based regimen, AMKL is notorious for its poor prognosis. With the continuous development of targeted drugs, the choice of chemotherapy regimens for AML patients has been gradually enriched. However, as far as we known, there is little data with this regimen in AMKL with decitabine and Bcl-2 inhibitor combined with imatinib. Herein, we reported the first case of adult AMKL with BCR-ABL positive successfully treated with decitabine and venetoclax combined with imatinib.