bluuebunny/crossref_metadata_2025 huggingface dataset:
Imagens da violência e a violência das imagens. as narrativas imagéticas de violências nos livros didáticos de história do ensino médio
Authors:   , Morais Ana Meyre de
Published: February 2025

Em diferentes períodos da História, a violência deixou-se ser traduzida por
práticas, intimidações, silenciamentos, reclusões, empreendidas por diversos povos,
ora de forma sutil, ora de forma explícita. Atualmente, muitas formas de violência
ganham destaques sensacionalistas nos diferentes espaços midiáticos, gerando por
vezes a banalização daquilo que deveria ser refletido, analisado e questionado
também nas salas de aula. Observam-se que as imagens da violência estão
disseminadas em diferentes lugares e meios. Os livros didáticos de História não são
a exceção, ainda que neles a violência seja pensada apenas como consequência de
fatos e atos dos personagens, dos heróis, dos inimigos, dos estrangeiros, do outro.
Os livros didáticos não se prestam apenas a divulgar, mas fazer com que a reflexão
seja consequência dos conteúdos ministrados. O ambiente escolar não se torna
somente lugar de produção de conhecimento, mas um espaço em que se pode
abordar sobre diferentes temas tão delicados. A proposta desta pesquisa pautou-se,
portanto, em analisar as imagens de cunho violento presentes nos livros didáticos de
História do Ensino Médio, para observar como este tema pode auxiliar os alunos a se
tornarem críticos, reflexivos e atuantes durante sua formação. Para tanto, a
metodologia contou com uma catalogação de imagens que podem ser traduzidas
como violentas, presentes na Coleção História Passado e Presente do Ensino Médio.
Em segundo momento, a análise das imagens foram referência documental
historiográfica que muito influencia na qualidade do ensino. Sobre as imagens,
procurou-se traçar uma crítica documental à luz das Histórias das Imagens. Para
tanto, teoricamente, esta investigação se ancorou em: Santaella (2012), Bittencourt
(2004, 2009), Müller (1995), Arendt (1970), Pinsky (1994), Cassiano (2013), Odalia
(2012), Bardin (2011), Gil (2008). O resultado demonstrou que as imagens de teor
violento oferecem meios para potencializar não apenas o Ensino de História, mas
também a forma como os discentes leem e percebem os registros iconográficos
Le nouvel esprit critique
Authors: Lévy Pierre
Published: February 2025

La grande majorité de la population mondiale est –ou sera bientôt –connectée à l’Internet, c’est-à-dire à un appareillage global de communication, de mémoire et de calcul encore inimaginable il y a un siècle et qui contient désormais la vie de la cité, de ses cimes scientifiques, artistiques et spirituelles à ses abîmes criminels. Du côté obscur de la force, les pouvoirs économiques, politico-militaires et culturels utilisent sans scrupules le nouveau médium algorithmique afin de combattre leurs adversaires et de séduire, exploiter ou asservir leurs sujets. Du côté lumineux, l’internet ouvre à une diversité d’information et à une liberté d’expression inconnues à l’âge des médias classiques. Nous commençons tout juste à explorer les possibilités de coordination à grande échelle et d’intelligence collective offertes par l’Internet.
Cancer Drug Targeting: Molecular Mechanism, Approaches, and Regulatory Framework
Authors: Chandel Rushikesh Somnath , Dewangan Hitesh Kumar
Published: February 2025

Novel vaccine formulations called nano vaccines which use nanoparticles (NPs) as adjuvants or
carriers, are being developed in place of conventional vaccines. The field of study on peptide-based nano vaccines
is enlarging fast as a result of combining antigenic peptides with nano-transport systems. This paper explores
advancements in anticancer nano vaccines, focusing on their mechanisms, challenges, and opportunities.
It discusses peptide nano vaccines, personalized vaccines, cancer prevention strategies, clinical translation,
and self-assembling multivalent nanovaccines. It also discusses nanocarriers' role in delivering tumorassociated
antigens and immune-stimulatory adjuvants. In 2024, the American Cancer Society projects over 2
million new cancer cases in the United States, marking the first year this milestone has been surpassed. This
equates to approximately 5,480 new cancer diagnoses daily. Additionally, over 611,000 cancer-related deaths
are expected, which translates to more than 1,600 deaths per day. The National Centre for Health Statistics
mentions the mortality data also shows the various types of cancer percentages. This guideline provides comprehensive
recommendations for sponsors submitting a novel drug under Investigation use of curative cancer
vaccinations, focusing on safety, effectiveness, dosage optimization, adjuvant use, patient group selection,
immune response monitoring, biomarker evaluation, multi-antigen vaccine development, phase-specific difficulties,
non-clinical testing, and legal frameworks, while also referencing relevant legal foundations and recommendations.
Exploring the Gut Microbiota as a Promising Target for Breast Cancer Treatment
Authors: Gale Dari Mahrokh Abouali , Ghaedrahmati Farhoodeh , Moalemnia Arash , Dezfouli Mitra Ansari , Savari Feryal , Zamani Amir Mohammad , Ahmadi Behnam , Nazarbeigi Mohammad , Farzaneh Maryam , Zehtabi Mojtaba
Published: February 2025

Breast cancer is a heterogeneous disease and highly prevalent malignancy
affecting women globally. Breast cancer treatments have been demonstrated to elicit
significant and long-lasting effects on various aspects of a patient's life, including
physical, emotional, social, and financial, highlighting the need for comprehensive
cancer care. Recent research suggests that the composition and activity of the gut
microbiota may play a crucial role in anticancer responses. Various compositional
features of the gut microbial population have been found to influence both the clinical
and biological aspects of breast cancer. Notably, the dominance of specific microbial
populations in the human intestine may significantly impact the effectiveness of cancer
treatment strategies. Therefore, the manipulation of the microbiota to improve the
anticancer effects of conventional tumor treatments represents a promising strategy for
enhancing the efficacy of cancer therapy. Emerging evidence indicates that alterations
in the gut microbiota composition and activity have the potential to impact breast
cancer risk and treatment outcomes. In this paper, we conduct a comprehensive
investigation of various databases and published articles to explore the impact of gut
microbial composition on both the molecular and clinical aspects of breast cancer. We
also discuss the implications of our findings for future research directions and clinical
strategies.
Molecular Identification and Characterization of the Causative Species of Cutaneous Leishmaniasis in Dezful City, Southwest Iran
Authors: Fatholahizadeh Atefeh , Mashayekhi Amir , Nayeri Tooran , Ghasemi Ezatollah
Published: February 2025

Background

Cutaneous Leishmaniasis (CL) represents a significant public health concern in endemic regions such as Dezful City, Iran, where cases have recently surged. This study aimed to identify and characterize the molecular profile of CL-causing species among patients in Dezful.

Methods

A total of 94 patients with skin lesions were enrolled, and demographic data, including age, gender, and residency, were collected. For each patient, two smears were obtained from the lesions: one for microscopic diagnosis and the other for DNA extraction. Subsequent molecular identification of the parasite was performed using Polymerase Chain Reaction (PCR). PCR amplification targeted the ITS1 region using specific primers Leish R (5’-AAA CAA AGG TTG TCG GGG-3’) and Leish F (5’-CAA CAC GCC GCC TCC TCT CT-3’).

Results

The results revealed that 100% of the CL cases were attributed to Leishmania major (L. major). Among the 94 patients, 67 (71.3%) were male, while 27 (28.7%) were female, with the highest incidence occurring in the age group of 11 to 20 years. Notably, lesions predominantly affected the hands (38.3%), whereas simultaneous involvement of the hand and trunk was present in only two cases (2.1%). Of the patients examined, 27 (28.7%) presented with a single lesion, 32 cases (34%) with two, 20 cases (21.3%) with three, and 15 (16%) with four or more lesions. Most of the lesions were observed to have a duration of one month (50%).

Conclusion

This study underscores the predominance of L. major in CL cases in Dezful, highlighting its epidemiological significance and the need for ongoing surveillance and control measures in the region, particularly focusing on controlling reservoirs (wild rodents).
Adherence Barriers to Antiretroviral Therapy in Men Who Have Sex with Men in O.R Tambo District, Eastern Cape
Authors: Manga Vuyolwetu , Kleinhans Atholl , Ebuenyi Ikenna Desmond , Oladimeji Olanrewaju
Published: February 2025

Background

Many barriers prevent Men Who Have Sex with Men (MSM) from complying with Antiretroviral Therapy (ART), including stigma and discrimination by healthcare workers at the clinic and in the community. There has yet to be much research into MSM's experience with stigma. The study aims to identify critical barriers to ART adherence faced by MSM in Mthatha and investigate how these barriers compromise ART adherence using qualitative research as an investigative tool.

Methods

A qualitative research study that utilized the snowball approach to conduct face-to-face interviews among MSM who live with HIV and are non-adherent to ART.

Results

The data analysis of this study produced six themes that include the following: unstable living arrangements, family rejection, health provider’s attitude, non-disclosure of HIV status to a sexual partner, treatment support, substance abuse, and stigma.

Conclusion

The participants in this study highlighted barriers and challenges to ART compliance, such as unstable living arrangements, family rejection, health providers' attitudes, non-disclosure of HIV status to a sexual partner, treatment support, substance abuse, and stigma. This project synthesized knowledge based on participants' responses and their suggestions on improving adherence to ART in MSM in the O.R. Tambo District.
The Health Status and Physical Activity Levels of Patients with T2DM in the Limpopo Province of South Africa
Authors: Malema Maphoko Phindile , Frantz Jose
Published: February 2025

Background

The prevalence of diabetes in Africa is increasing rapidly, reflecting broader global trends. In Limpopo communities, diabetes prevalence is relatively low at 3.2%, but it rises to 8.8% in urban areas. This disparity highlights an urgent need for public health interventions, particularly in urban settings where only 60% of people are aware of their condition. This signifies a substantial burden of undiagnosed diabetes, which necessitates public health action.

Aim

This study aimed to determine the health status and physical activity levels of patients with T2DM in the Elias Motsoaledi Municipality, Limpopo Province, South Africa.

Methods

A quantitative research approach was utilized, following a descriptive cross-sectional design. The current study included 202 participants in the Elias Motsoaledi Municipality, South Africa. The study targeted participants aged 18 years and older from Elias Motsoaledi Municipality. Recruitment was facilitated through local Department of Health facilities. A convenient sampling method was used to recruit participants based on Slovin’s formula to obtain the sample size for the study. Descriptive statistics, including frequencies and chi-square tests, were employed to analyze the data.

Results

The results revealed that most participants suffered from additional non-communicable diseases alongside diabetes. Despite the benefits of participating in physical activities in managing diabetes, the results demonstrated that very few participants did not engage in any form of physical activity. The study identified various challenges and barriers that hinder their ability to engage in physical activities.

Conclusion

The study concluded that participants have a heavy reliance on medication among diabetic patients in the Elias Motsoaledi Municipality, with minimal emphasis on lifestyle modifications, such as diet and physical activity, for diabetes management. Therefore, there is a need for enhanced education and awareness programs that focus on comprehensive diabetes management strategies, including physical activity and nutrition, especially in resource-constrained settings like the Elias Motsoaledi Municipality.
Integrity and Transparency in Sports: A Survey Review
Authors: Costa Silvia , Silva António J. , Dias Tatiana , Marinho Daniel A. , Batalha Nuno M. , Roque Rodrigo , Afonso Carolina , Aminova Munira , Ferraz Ricardo
Published: February 2025

Over the years, integrity and transparency have become the fundamental pillars of ethical conduct in sports, ensuring equal and fair competition. However, in recent years, concerns about various ethical issues and misconduct in sports have emerged and garnered considerable attention from researchers. In response to these issues, this article aims to provide a comprehensive analysis of the literature, attempting to identify fundamental indicators of integrity and transparency in sports that can be measured and assessed. The research methodology employed a set of search terms that were combined in multiple ways with various keywords, including “sports,” “determinants,” “indicators,” “integrity,” “transparency,” “responsibility,” and “governance.” The period of analysis spanned from 2000 to the present day. A filter was applied to remove duplicates, incomplete documents, studies prior to 2000, and studies in other fields. Finally, after using these specific criteria, a total of 38 articles were selected for further analysis. The results indicate that a total of 15 indicators can be measured and controlled for the world of sport to prosper in terms of integrity, ethics, and transparency.
The Discovery of Forensics Chemistry Latent Fingerprints: An Article Review
Authors: Yousif Eamd , Ahmed Dina , Ibraheem Hanan , Yusop Rahimi , Zainulabdeen Khalid , Redwan Amamer
Published: February 2025

Forensic chemistry distinguishes itself from other branches of chemical sciences by the necessity to cater to the requirements of both the scientific and legal communities. Its research, application, and presentation are uniquely geared towards meeting the needs of these two domains. Consequently, forensic chemistry research is inherently practical and derived, emphasizing metrology (the science of measurement) and validation. Forensic chemistry has evolved beyond its initial analytical origins and now encompasses a broader range of chemical sciences. As the field expands, established forensic practices are being reevaluated, extending beyond drug analysis and toxicology to encompass diverse areas such as combustion chemistry, materials science, and pattern evidence. Chemistry has been used more and more to help with criminal investigations and forensic chemistry has become an important topic of study for students at all levels of education. The excitement of carrying out chemical tests is increased with the chance to explore a criminal incident. Both educators and students are consistently intrigued by the prominence of chemistry in crime scene investigations depicted in television shows. Fingerprint analysis, a key component of forensic science, has been adapted for every educational level. From elementary school students creating fingerprints with ink to the exciting (and messy) activity of revealing latent fingerprints through dusting, educators have found engaging ways to incorporate forensic science lessons. Superglue, readily available commercially, allows anyone interested to show its capabilities for detecting latent prints. Forensic science or forensic chemistry courses in high school and postsecondary education often include experiments involving the revelation of latent fingerprints. Latent fingerprints are formed when a person touches a surface, leaving behind a nearly transparent chemical residue that mirrors their unique skin ridge patterns. Latent fingerprints are likely to be left on surfaces every time you contact or grab them. To improve the contrast between the fingerprint residue and the surface it has been applied on, many methods have been established. Abundant and resilient, latent prints are unintentionally left behind on the surfaces you touch daily. Specialized techniques can reveal many of these latent prints, highlighting their potential significance in forensic investigations.
Chemistry Learning Anxiety Profile of Phase E Students of Public Senior High School in Sleman Regency
Authors: Hindun Hindun , Pratomo Heru
Published: February 2025

Chemistry is still considered a subject that is difficult for some students to understand, thus triggering chemistry learning anxiety or chemophobia. This research aims to analyze the level of anxiety in studying chemistry in tenth-grade students at public senior high schools in Sleman Regency in participating in phase E chemistry learning. This quantitative research uses a survey method with a cross-sectional design. A total of 413 tenth-grade students from six public senior high schools in Sleman Regency were selected using cluster random sampling as the research sample. The instrument used is the chemistry learning anxiety scale, which consists of 50 statement items. The data results were analyzed using ideal assessment categories. The findings of this research revealed that students have low anxiety about studying chemistry in the phase E of chemistry learning. Low chemistry learning anxiety is a good asset for students to be able to follow and understand chemistry learning well in phase E and the following phases. Male students and students with good academic achievement tend to have lower chemistry learning anxiety than female students and students with less good academic achievement.
Analysis of Teacher Needs for A Contextual Chemistry Module Based on Multiple Representation Integrated Islamic Values in Hydrocarbon Materials
Authors: Salsabila Salma , Aznam Nurfina
Published: February 2025

This research aims to analyze the need for the development of a contextual chemistry module based on multiple representations integrated with Islamic values in hydrocarbon materials. This research method is qualitative descriptive research with data collection techniques in the form of structured interviews using interview guidelines for chemistry teachers at Madrasah 'Aliyah. The data analysis technique used is Miles-Huberman Interactive Analysis with stages of data collection, data display, data reduction, and drawing conclusions. The research findings reveal: 1) The curriculum implemented in schools is the independent curriculum. 2) Most students show a lack of interest in chemistry, particularly in hydrocarbon topics. 3) Students' religious character has declined. 4) The integration of Islamic values in learning is suboptimal and teachers possess limited knowledge of scientific developments. 5) No learning resources based on multiple representations and integrated with Islamic values are available. Based on the needs analysis conducted, a chemistry module with a contextual approach based on multiple representations integrated with Islamic values in hydrocarbon materials can be developed.
Development of ARSA (Augmented Reality Struktur Atom) Based on Android as an Independent Learning Resource for High School Students
Authors: Pratama Irfansyah Nabilazuardi , Priyambodo Erfan
Published: February 2025

This research aims to determine the characteristics, feasibility, and student responses to the Android-based ARSA as an independent learning resource for high school/Islamic high school (SMA/MA) students. The research method used is a mixed-methods approach with an exploratory sequential design. The data obtained includes qualitative descriptive data in the needs analysis, expert validation test, and peer reviewer feasibility test. For the feasibility test by reviewers and the student response test, qualitative data were converted into quantitative data using a Likert scale and then analyzed using ideal conversion guidelines to determine the feasibility of the product in each aspect and overall. The research results show that the ARSA learning resource has the following characteristics: it features interactive 3D visualizations of atomic models, can be used without an internet connection, and serves as an independent learning resource for SMA/MA students. The ARSA learning resource was declared feasible for use after adjustments were made based on comments/suggestions from prospective teachers as peer reviewers and chemistry teachers as reviewers. It was also declared suitable for use by students.
Validation of the Beck Depression Inventory in U.S. Hispanic Patients with Chronic Kidney Disease
Authors: Ricardo Ana C. , Park Sunho , Carmona-Powell Eunice , Larkin Claire , Quiroga Arabela , Fischer Michael J. , Lora Claudia M. , Chen Jinsong , Missikpode Celestine , Pineda Madison , Zhang Xiaoming , Hsu Jesse Y , Shankman Stewart , Lash James ,   the CRIC Study Investigators
Published: February 2025

Background:

Depression is common in patients with chronic kidney disease (CKD). Self-report scales including the Beck Depression Inventory (BDI) have been evaluated in non-Hispanic adults with CKD for screening of depressive symptoms. However, the BDI has not been validated in Hispanic adults with CKD.

Methods:

We investigated the screening characteristics of the BDI in 248 Hispanic adults (164 with CKD and 84 with end-stage kidney disease [ESKD]) enrolled in the Hispanic Chronic Renal Insufficiency Cohort Study. Two trained study personnel administered the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders Fourth Edition Disorders (SCID) which served as the gold standard measure for the diagnosis of major depression.

Results:

Among the 164 participants with CKD, mean (SD) age was 61 (0.8) years, 37% were female, 77% spoke primarily Spanish, mean (SD) eGFR was 37 (1.3) ml/min/1.73m2 and median (IQR) proteinuria was 0.4 (0.1-2.0) g/g. Using the SCID, 24 (15%) were classified as having current major depressive disorder. The best cutoff BDI score to identify current major depression disorder based on the receiver operating characteristics curve was 16. Sensitivity was 88%, specificity was 84%, positive predictive value was 49% and negative predictive value was 98%. Similar results were found in participants with ESKD.

Conclusion:

A BDI score of ≥16 was sensitive and specific for identifying major depression in U.S. Hispanic adults with CKD and ESKD, which is a higher cutoff than reported for non-Hispanic patients with CKD. These differences in psychometric properties should be considered in future research and clinical practice.
ЧЕТЫРЕ СПОСОБА ДЕКАПСУЛЯЦИИ ПОЛУПРОВОДНИКОВЫХ ПРИБОРОВ
Authors: Варламов П.
Published: February 2025

В процессе производства полупроводниковых приборов часто возникает
задача анализа работы компонента при определенных условиях
(воздействие ионизирующего излучения для изделий космического
назначения, поиск неисправностей интегральных схем, исследование
приборов на отказоустойчивость и т.д.). Для решения подобных задач
необходимо получить доступ к кристаллу ИС, сохраняя при этом ее
целостность и функциональные свойства. Направление такого рода
исследований получило название «декапсуляция». В статье рассмотрены
современные методы декапсуляции полупроводниковых приборов,
их достоинства и недостатки, способы применения.
Mulheres na ciência e no cinema: 20 filmes para celebrar 25 anos de “Scientia”
Authors: Soares da Costa Verônica
Published: February 2025

O texto apresenta uma resenha crítica da obra “Mulheres na ciência e no cinema”, organizada por Ana Carolina Vimieiro Gomes e Gustavo Rodrigues Rocha, e publicado em 2024 pela ocasião dos 25 anos do Scientia — Grupo de Teoria e História das Ciências, da Universidade Federal de Minas Gerais (UFMG). A obra é composta por capítulos que exploram obras audiovisuais diversas que tratam da vida e obra de mulheres na ciência, ou que debatem temas afins à presença de mulheres no empreendimento científico.
Characteristics of the COVID-19 epidemic process in the Volga Federal District in 2020–2023
Authors: Tuzova I. N. , Sarskov S. A. , Kuzovatova E. E. , Polyanina A. V. , Zaitseva N. N.
Published: February 2025

The aim of the study was to determine characteristics of COVID-19 epidemic process in the Volga federal district in 2020–2023.

Materials and methods. Analysis of the COVID-19 epidemic process progress was carried out from March 30, 2020 to December 31, 2023. We used information from the website «report.gsen.ru», materials from the national platform for the aggregation of SARS-CoV-2 genome data — VGARus, the official website of Rospotrebnadzor, the information portal Stopcoronavirus rf, data from the official World Health Organization (WHO) website, weekly reports submitted by the Rospotrebnadzor of the subjects of the Volga Federal District.

Results and discussion. The average district incidence rate of a new coronavirus infection was 1280.70/0000 in 2020, 3863.00/0000 in 2021, 7352.20/0000 in 2022, 1398.30/0000 in 2023. In the period from 2020 to 2023, the prevalence of persons aged 30–49 years and 50–64 years in the structure of COVID-19 cases was recorded. The largest proportion of severe cases was recorded in 2022 and 2023 (58.8% and 57.9%, respectively), the smallest — in 2020 (37.6%). The average district mortality and lethality rates were — 20.60/0000 and 1.6% in 2020, 150.80/0000 and 3.9% in 2022, 46.90/0000 and 0.6% in 2022, 3.00/0000 and 0.2% in 2023 respectively.

Conclusion. In the period 2020–2023, the COVID-19 incidence rate in general in the Volga Federal District varied, there was an increase in the proportion of mild severe cases, as well as a decrease in mortality and lethality rates, which is associated with a change in circulatingSARS-CoV-2 genovariants, the formation of population immunity, and the organization of a comprehensive system of anti-epidemic measures.
Duration of SARS-CоV-2 virus shedding in COVID-19 patients with HIV infection
Authors: Lioznov D. A. , Pobegalova O. E. , Sabadash N. V. , Karnaukhova E. Yu. , Antonova T. V. , Komissarov A. B. , Ivanova A. A.
Published: February 2025

The aim: to describe the duration of SARS-CoV-2 virus shedding in patients with HIV infection and to identify factors associated with prolonged viral shedding.

Materials and methods: in a prospective study, the clinical and laboratory characteristics of COVID-19 and HIV infection and the duration of SARS-CoV-2 virus shedding were compared in 170 patients, titers of virus neutralizing antibodies to SARSCoV-2 were identified in 68 patients; pathogen genotyping was performed in 36 patients. Statistical analysis was carried out using the IBM SPSS Statistics package.

Results and discussion: there were no significant differences in the duration of SARS-CoV-2 virus shedding in patients with varying severity grade of COVID-19; a negative relationship between the titer of virus neutralizing antibodies to SARS-CoV-2 and viral shedding duration was revealed. In 35.9% of patients (61 persons), the persistence of the virus lasted for more than 21 days, this group was characterized by an unfavorable course of HIV infection in the absence of ART, significantly lower CD4 cell values and a higher HIV viral load in the blood. Virus shedding was shown to be significantly longer in patients with B.1.1 strain versus other SARS-CoV-2 gene variants. Mutations in the Spike protein gene that increase the infectious ability of the pathogen and reduce its sensitivity to neutralizing antibodies were found in 4 patients.

Conclusion: the severity of COVID-19 did not affect the duration of SARS-CoV-2 virus shedding in patients with HIV infection. Long-term persistence of the virus was discovered in patients with severe immunodeficiency (CD4<200 cl/μl) in the absence of ART. Patients with prolonged viral shedding pose an epidemiological risk in regard to developing new mutational variants of the pathogen.
COMPETENCY DEVELOPMENT AND BUSINESS GRADUATE EMPLOYABILITY SKILLS: MODERATION BY ACADEMIC ACHIEVEMENT ON THEORY OF COGNITIVE APPRENTICESHIP
Authors: Omar Bishanani , Zulnaidi Hutkemri , Alias Norlidah
Published: February 2025

This research aims to examine the moderation effect of academic achievement in the relationship between competency development and business graduate employability skills at vocational colleges in Malaysia. Applying a purposive sampling method, data were gathered among students studying business programs at vocational colleges in Malaysia and were analyzed using Smart Partial Least Squares (PLS). The findings indicated significant positive associations between competency development and business graduate employability skills at vocational colleges in Malaysia. Meanwhile, academic achievement was the opposite as there was an insignificant effect towards the business graduate employability skills for vocational colleges. Academic achievement has not moderated the relationship between competency development and business graduate employability skills for vocational colleges. It is expected that this study could provide a better understanding of the need of industry for competency development for business graduate employability skills for vocational colleges and institutions improving students’ academic achievement.
DETERMINING GAMIFICATION ELEMENTS THROUGH EXPERTS’ PERSPECTIVES FOR TEACHING ENGLISH LANGUAGE
Authors: Sharizal Sabrina Adia Mohd , Razak Rafiza Abdul , Hassan Norshahida
Published: February 2025

This paper explores experts’ opinions and perspectives from two different fields of study: English language teaching and instructional technology, in regards to determining the key gamification elements or essentials needed to teach pre-university students in their English language classrooms. Four (4) experts who were experienced in teaching and evaluating pre-university students were chosen, two from fields of English language teaching and instructional technology respectively. A series of interviews were conducted to gain the opinions and perspectives on the implementation of gamification in the English language classroom. Based on the findings, they discussed the fundamentals of applying gamification on attracting students to utilise the pedagogical aspect. A prompt list of instructions was provided by the experts based on their experiences on how to make the approach more effective and enhance students’ focus and English language skills in the classroom to be implemented in the real world. The paper's conclusion outlines the practical ramifications and offers ideas for further research.
INVESTIGATING THE NEEDS TO DEVELOP ENGLISH FOR SPECIFIC PURPOSE PEDAGOGICAL STRATEGIES FOR ALLIED HEALTH NOVICE
Authors: Lopez Daisy Marie , Razak Rafiza Abdul
Published: February 2025

The present study aimed to investigate the academic and professional English language communicative needs of allied health novice students in Malaysia. Language proficiency is crucial for doctors as they communicate with patients, peers, and other healthcare professionals. Although proficiency in English is a part of the admission requirement, there is a gap in the knowledge of medical students’ perception. This study will also focus on the factors enhancing English language skills from the perspective of students to contribute towards the process of English for medical purposes curriculum development, especially in English communication. Data will be collected through focus group interviews with students.
TAHAP PENERIMAAN APLIKASI CANVA DALAM PEMBELAJARAN: SATU KAJIAN KES
Authors: Hui Ching Melvina Chung
Published: February 2025

The development of digital technology has introduced many digital tools in the form of applications that are offered for free, especially for educators and students. Furthermore, in 21st-century education, an important component is utilizing digital technology in teaching and learning. Therefore, the Canva application has increased its popularity among users. This study aims to identify the level of acceptance of Canva application usage among IPG students. This study is a case study involving 79 PISMP students majoring in Malay Language studies. The instruments used in this study involve a questionnaire through Google Forms and structured interviews. The study results showed that the acceptance level of the Canva application among IPG students has very high mean values for all three aspects, namely enjoyment in using the Canva application with a mean value of 4.59, the usefulness aspect of the Canva application in learning with a mean value of 4.49, and students' attitude towards the use of Canva with a mean value of 4.64. In addition, interview findings also showed positive acceptance towards the Canva application. In conclusion, using the Canva application is the main choice among IPG students due to its advantages, in addition to being equipped with a comprehensive design tool package that makes it easier for users to complete assignments in one place.
SDG 9-industry, innovation and infrastructure: A review on companies in the BIST sustainability index
Authors: Kazan Gülçin , Uzun Kocamış Tuğçe , Türüdüoğlu Öker Figen
Published: February 2025

The Sustainable Development Goals (SDGs), adopted by the United Nations (UN) in 2015, consist of 17 goals that outline the global sustainability agenda. These goals aim to promote sustainability in economic, social, and environmental dimensions by guiding institutions and organizations in identifying priority development areas and processes. Sustainability reports, on the other hand, are reports prepared by companies and organizations to explain their impacts on environmental, social, and governance (ESG) dimensions. These reports are critical documents that comprehensively explain the sustainability performance and future goals of companies to their stakeholders (Bajwa et al., 2024). In this study, the sustainability reports of 25 companies traded on the Borsa Istanbul (BIST) sustainability index are analyzed in terms of content in the context of goal 9 (SDG 9) — building resilient infrastructure, inclusive and sustainable industrialization, and promoting innovation. Within the scope of the study, firstly the company reports were examined through keywords, then the first five company reports where the keywords were used the most were subjected to in-depth content analysis to examine the compliance of the work carried out by the companies with the SDG 9 targets and the progress made by the companies towards this target.
Development of an Electroanalytical Method for the Determination Dicyclomine Hydrochloride Using Pencil Graphite Electrode
Authors: P Vijay Pattar , L Nagappa Teradal
Published: February 2025

Electroanalytical methods are being used widely for the determination of pharmaceutically active ingredients as they are
known for their sensitivity and selectivity. In the present study, the electrochemical behavior of dicyclomine hydrochloride is
investigated at pencil graphite electrode for the first time and developed an alternative analytical method for its determination
in analyte fortified samples. Dicyclomine hydrochloride exhibited an oxidation peak at 1.023 V in phosphate buffer of pH 7 in
the forward scan and no peak in the backward scan suggesting that the electrochemical behavior is irreversible. Influence of
pH of phosphate buffer solution and scan rate on electrochemical behavior of dicyclomine hydrochloride is explored. Under
optimized conditions, an alternative analytical method is developed for the determination of Dicyclomine hydrochloride in
bulk and analyte fortified urine samples. A linear response is observed between anodic peak current and concentration of
Dicyclomine hydrochloride in the range of 0.1 to 0.9 µM with the limit of detection of 0.06 µM. Further, practical utility of
the developed analytical method was established by determining the Dicyclomine hydrochloride in analyte fortified urine
samples. Recovery values is found to be more than 97.14% indicated that the developed method is accurate for Dicyclomine
hydrochloride determination.
Applications and Challenges of Nano Medicine for Covid-19 Outbreak: The Potential Relevance of Therapeutic and Diagnostic Approaches for Treatment
Authors: S Sheeba , M Murugan , AS Suman Sankar
Published: February 2025

The recent coronavirus 2019 (COVID-19) outbreak was caused by the severe acute respiratory syndrome coronavirus 2 (SARSCoV-2). Finding newer therapeutic targets is necessary because, despite the fact that pandemics like SARS-CoV and Middle East
respiratory syndrome coronavirus (MERS-CoV) have been around for almost 20 years, no effective medication against the CoV
family has been approved. Compared to conventional PCR tests, nanoparticle-based biosensors and point-of-care testing kits
yield faster and more accurate issues with toxicity. In order to successfully incorporate nanotechnology into standard medical
practice and improve readiness for upcoming pandemics, several problems must be resolved. With an emphasis on medication
administration, diagnostics, vaccinations, and protective gear, this study investigates several nanotechnology-based strategies
for COVID-19 management. Engineered nanoparticles (NPs) are used in Nano medicine to improve immunological response,
targeting, and medication stability while lowering toxicity. The research emphasizes how important Nano medicine is in the
fight against COVID-19 by improving drug delivery, diagnostics, vaccinations, and protective gear. The findings show that, in
comparison to traditional methods, nanotechnology offers better efficacy, tailored distribution, and fewer adverse effects.
To assurance the wellbeing, effectiveness, and moral application of Nano medicine in healthcare, stringent regulations are
required.
Symmetric Nature of Positive-Negative Matters, and Its Generalization and Test
Authors: C Yi-Fang
Published: February 2025

Based on the negative matter as unified dark matter and dark energy, we first derive its three basic formulas on gravity, total
energy, and field equations of general relativity. Second, we research astronomy and cosmology on the negative matter, and
propose that a new test way on galaxies with different positive and negative matters have different curves of the rotational
velocity with distance. Third, we discuss physics and other natural sciences of the negative matter, and search the cosmic wave
function and corresponding quantum theory. The negative matter is calculable, observable and testable, and may be changed
and developed. If the negative matter is confirmed by the observation, it will open up a new world.
Automatizando a descoberta
Authors: Rodrigues Mariana Vitti , Gonzalez Maria Eunice Quilici
Published: February 2025

O objetivo deste artigo é investigar em que medida a inferência abdutiva pode ser automatizada. Para isso, apresentamos a noção peirceana de abdução, segundo a qual a abdução é o processo de geração e seleção de hipóteses explicativas que orientam a investigação científica (CP 5.171; 1903). Em seguida, apresentamos o conceito contemporâneo de abdução, caracterizado como Inferência à Melhor Explicação (IME), cujo objetivo é selecionar uma hipótese, entre um conjunto de hipóteses disponíveis, considerando seu potencial explicativo em termos de probabilidade e uberdade (Lipton, 2004). Subsequentemente, discutimos IME em relação ao Bayesianismo, segundo o qual agentes racionais atualizam seus graus de crença em uma proposição com base em novas evidências e considerações explicativas. Para ilustrar nossa análise, apresentamos o software denominado AI-Descartes, um sistema de Inteligência Artificial de código aberto que combina raciocínio lógico com regressão simbólica, projetado para derivar descobertas científicas a partir de conhecimento axiomático e dados experimentais (Cornelio et al., 2023). Por fim, apresentamos considerações sobre a relevância do estudo da abdução no contexto da Inteligência Artificial.
УСЛОВИЯ ОПТИМАЛЬНОСТИ ВТОРОГО ПОРЯДКА УГЛОВ ОРИЕНТАЦИИ ВОЛОКОН СЛОЁВ ТОНКОЙ КОМПОЗИТНОЙ ПЛАСТИНЫ ДЛЯ МАКСИМИЗАЦИИ НАГРУЗКИ ПОТЕРИ УСТОЙЧИВОСТИ
Authors: Селюгин Сергей
Published: February 2025

Рассмотрена задача максимизации нагрузки потери устойчивости для тонких композитных пластин за счёт выбора наилучшей локальной ориентации слоёв. Пластины – линейно-упруги и подчиняются гипотезе прямых нормалей Кирхгоффа. На основе вариационного принципа, описывающего устойчивость пластины, получены и проанализированы необходимые условия локальной оптимальности второго порядка в этой задаче. Сравнение решений для условий оптимальности первого и второго порядков показывает, что решения для условий второго порядка справедливы только для части решений условий первого порядка. Отобранные таким образом совместные решения (для условий обоих порядков) и ведут к максимизации нагрузки потери устойчивости. Одним из таких решений является совпадение локального направления волокон и главного направления наибольшей по абсолютной величине главной кривизны поверхности пластины, деформированной по собственной форме потере устойчивости. При определенных условиях для констант материала и кривизн деформированной поверхности возможно дополнительное решение с ориентацией волокон вдоль второго главного направления кривизн. Приведен пример, иллюстрирующий полученные результаты.
Analysis of the Hail Phenomenon in Bistrița-Năsăud County in 2024: Localization, Impact, Perception, and Mitigation
Authors:   Faculty of Geography, Babeș-Bolyai University Cluj-Napoca, Bistrița Extension, Bistrița, Romania. Email: andras.barta@ubbcluj.ro, Barta Andras-István , Raboșapca Irina ,   Faculty of Geography, Babeș-Bolyai University Cluj-Napoca, Bistrița Extension, Bistrița, Romania. Email: irina.rabosapca@ubbcluj.ro, Bilașco Ștefan ,   Faculty of Geography, Babeș-Bolyai University, Cluj-Napoca, Romania. Email: stefan.bilasco@ubbcluj.ro, Modovan Aurelian Cosmin ,   N. A. Romanian Waters, S.G.A. Bistrița-Năsăud, Romania. Email: cosmin.moldovan@sgabn.dast.rowater.ro, Mihăiescu Tania ,   Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania. Email: tania.mihaiescu@usamvcluj.ro
Published: February 2025

Analysis of the hail phenomenon in Bistrița-Năsăud County in 2024: localization, impact, perception, and mitigation. This study examines the hail phenomenon that impacted Bistrița-Năsăud County during the period 2022-2024, with a particular focus on the significant hail events of 2024. The research integrates climatological data, meteorological observations, and locally sourced information to evaluate the frequency, localization, and intensity of hail across the region. Specific emphasis is placed on areas such as Săsarm, where the June 2024 hailstorm inflicted severe damage on households, agricultural infrastructure, and public amenities. The study not only documents the material and economic consequences but also investigates the community’s perception of the implemented preventive and mitigation strategies, such as anti-hail systems and agricultural insurance policies. Findings underline that while some measures were in place, there remains a critical need for more robust and effective climate risk management approaches, particularly in high-risk areas like Bistrița-Năsăud County. Enhanced public awareness campaigns and investment in adaptive technologies are identified as key steps toward increasing community resilience.
Keywords: hail, storm, intensity, extension, damage, management, perception, mitigation.
Modifikasi Karbon Berpori Eceng Gondok Doping Nitrogen Untuk Matrik Katoda Baterai Litium Sulfur Dengan Kapasitas Tinggi
Authors:   Universitas Padjadjaran, Nurhilal Otong , Hidayat Sahrul , Sumiarsa Dadan , Risdiana Risdiana
Published: February 2025

Karbon berpori dari biomassa menjadi kandidat potensial untuk matrik katoda baterai litium sulfur. Karbon berpori harus memiliki konduktivitas listrik yang tinggi untuk meningkatkan kontak elektrik sulfur yang bersifat isolator. Modifikasi karbon berpori doping N diperlukan untuk meningkatkan kinerja baterai litium sulfur. Pada penelitian ini telah dibuat karbon berpori Eceng Gondok doping N, selanjutnya dikompositkan dengan sulfur dan diaplikasikan untuk katoda baterai litium sulfur. Hasil pengujian dengan FTIR menunjukkan adanya gugus C=N pada 1657 cm-1. Hasil pengujian SEM-EDS terhadap komposit karbon berpori doping N/sulfur diperoleh kadar sulfur sebesar 66,95 wt% untuk rasio 1:2,5. Hasil pengujian dengan four line probe (FLP) diperoleh konduktivitas listrik karbon berpori doping N sebesar 17,16 x 10-2 S/cm, komposit karbon berpori doping N/sulfur sebesar 14,61 x 10-4 S/cm. Katoda baterai litium sulfur telah berhasil dibuat dari komposit KBEGN/S dengan ketebalan 200 mm dan kandungan sulfur sebesar 4,93 mg/cm2. Hasil pengukuran charge-discharge baterai diperoleh kapasitas pengosongan awal sebesar 584 mAh/g. Nilai kapasitas pengosongan awal yang diperoleh lebih besar dari baterai dengan karbon berpori tanpa doping N sebesar 312 mAh/g untuk kandungan sulfur 3,57 mg/cm2.
Development of Photo Electrocatalytic Chemical Oxygen Demand Design (PECOD) Sensor using Highly Ordered Titanium Dioxide Nanotube Arrays Electrodes
Authors:   Universitas Indonesia, Utami Chichi Amne , Syauqi Muhammad Iqbal , Ningsih Sherly Kasuma Warda , Wibowo Rahmat , Gunlazuardi Jarnuzi
Published: February 2025

Population growth, industrialization, and the need to ensure water quality have fostered the demand for analytical methods and tools to determine one of the important values of water quality standards. The oxygen demand of a given water matrix provides valuable information about the presence of organic compounds in a sample. The TiO2-based photoelectrocatalytic COD (PECOD) method offers a faster, more efficient, and more accurate alternative than conventional methods. Highly ordered TiO2 nanotube arrays (HOTNAs) were synthesized by anodizing titanium metal at 45V for 2 hours. HOTNAs/FTO photoanodes are used to oxidize organic compounds in water. HOTNAs/FTO photoanode has a bandgap of 3.4eV and a current density of 0.29 mA/cm2. Environmental samples were tested with the PeCOD sensor using glucose and mixed compound addition standards method. Water samples taken from local small ponds, namely Danau Kenanga, Danau Agathis, and typical wastewater of Laundry activity reveal COD values of 15,4659 to 15,9571 mg/L O2; 19,0500 to 19,6179 mg/LO2; 445,2336 to 449,7830 mg/L O2; respectively. The developed PECOD sensor performed well and provided analytical results that were not much different from conventional methods, with an error percentage below 10%.
24-Methylenecycloartanol Isolated from The Fruit Peel of Matoa (Pometia pinnata) and Its Activity as an Antibacterial against Staphylococcus aureus and Escherichia coli
Authors:   Universitas Muhammadiyah Semarang, Anwar Risyandi , Arnov Steffi Triany , Putri Ghesta Alifka , Sinaga Siska Elisahbet , Naini Al Arofatus , Supratman Unang
Published: February 2025

Triterpenoids are compounds with highly diverse chemical structures and exhibit interesting biological activities such as antiviral, antibacterial, anti-inflammatory, and anticancer properties. The matoa plant (Pometia pinnata), belonging to the genus Pometia from the family Sapindaceae, has been used in traditional medicine and shows potential as an antibacterial agent. The purpose of this research was to isolate and determine the chemical structure of triterpenoids from the peel of the matoa fruit (P. pinnata) and to evaluate their antibacterial activity against Staphylococcus aureus and Escherichia coli. The ethyl acetate extract from the peel of P. pinnata demonstrated significant antibacterial activity. In this study, a triterpenoid compound was identified, and its chemical structure was determined using spectroscopic methods, including UV, IR, MS, 1H-NMR, 13C-NMR, and 2D-NMR, as well as by comparing data from the literature. The compound was identified as a cycloartane-type triterpenoid known as 24-methylenecycloartanol. The compound was then tested for antibacterial activity against S. aureus and E. coli. The test results showed a minimum inhibitory concentration (MIC) of 500 μg/mL for both bacteria, which was categorized as very weak