bluuebunny/crossref_metadata_2025 huggingface dataset:
PHARMACOKINETIC PROFILE OF 75 MG CLOPIDOGREL IN PLASMA OF INDONESIAN HEALTHY SUBJECTS BY ULTRA HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY
Authors: Harahap Yahdiana , Putri Ganesya Rita , Suryadi Herman
Published: December 2018

Objective: This study aimed to determine clopidogrel in plasma to obtain its pharmacokinetic profile using ultra-high-performance liquidchromatography-tandem mass spectrometry (UPLC-MS/MS).Methods: Clopidogrel analysis was performed in vivo by UPLC-MS/MS using validated methods. Subjects received 75 mg clopidogrel, and plasmasamples were collected at 14 time points after 0 baseline (pre-dose): 0.25, 0.5, 0.75, 1, 1.25, 1.5, 2, 3, 4, 8, 12, 18, and 24 h.Results: A linear calibration curve was produced in the range of 20–5.000 pg/mL. This method fulfills the criteria for validation according to theEuropean Medicines Agency guidelines. The obtained pharmacokinetic profile of clopidogrel was as follows: Maximum concentration=1.146 ng/mL,time at maximum concentration (tmax)=1 h, half-life (t½)=7.01 h, area under curve (AUC)0−t=7.420 ng h/mL, and AUC0−t=8.111 ng h/mL.Conclusion: Clopidogrel analysis using a UPLC/MS-MS system with liquid-liquid extraction method was successfully conducted using plasma samplesfrom three healthy subjects who administered 75 mg of clopidogrel tablet.
PREPARATION OF POWDER FROM BROWN SEAWEED (SARGASSUM PLAGYOPHYLLUM) BY FREEZE-DRYING WITH MALTODEXTRIN AS A STABILIZER
Authors: Anwar Effionora , Erianto Hilmia , Putri Kurnia Sari Setio
Published: December 2018

Objective: The aim of this study was to prepare powder from liquid extract with maltodextrin dextrose equivalent 10–15 as a stabilizer using a freezedryingmethod to maintain stability during drying process and extend storage time.Methods: Powders were prepared for four formulas: F1 (without maltodextrin), F2 (2.5% maltodextrin), F3 (5% maltodextrin), and F4 (10%maltodextrin). Powder from the four formulas was characterized by its phlorotannin concentration, antioxidant activity, water content, morphology,particle size distribution, pH, and organoleptic activities.Results: F4 was the best formula because it contained the highest phlorotannin concentration (113.06±1.36) or 0.25%, highest percentage ofinhibition concentration50 (IC50) (4.06% at a concentration of 5000 ppm), and lowest water content (5.16%); moreover, in a stability test, F4 exhibiteda more stable phlorotannin concentration and lower water content than F1, with an optimal storage temperature of 4°C.Conclusion: Maltodextrin can improve the stability bioactive compounds during the freeze-drying process and storage time.
QUALITATIVE REVIEW OF ANTIBIOTIC USE FOR NEONATAL SEPSIS
Authors: Wei Tjio Ie , Ascobat Purwantyastuti , Rohsiswatmo Rinawati , Instiaty Insti
Published: December 2018

Objective: The aim of this study is to evaluate the antibiotic use in neonates with sepsis.Methods: An observational retrospective study was conducted using medical records of neonates diagnosed with early-/late-onset sepsis who wereprescribed antibiotics and who were treated in the neonatal intensive care unit (NICU) at the Dr. Cipto Mangunkusumo Hospital between January 1 andDecember 31, 2015. Patient records were screened for antibiotic use; qualitative analyses were performed using the Gyssens algorithm. Concordanceof empirical antibiotic prescriptions with subsequent blood culture and sensitivity tests was evaluated.Results: A total of 176 sepsis cases included 80 and 96 neonates with normal and low birth weights (LBWs), respectively. Ampicillinsulbactam+gentamycin, which is indicated in local guidelines as the first-line antibiotic combination for neonatal sepsis, was most frequentlyprescribed. In the normal birth weight group, appropriate antibiotic use (Gyssens Category I) was found in 89.7% of cases, whereas Gyssens Category V(no indication) was found in 4.54% of cases. In the LBW group, 88.1% and 6.2% of cases were included in Gyssens Categories I and V, respectively.Only 17.5% and 13.5% cultured blood specimens from normal and LBW groups, respectively, yielded positive results; the most commonly identifiedbacteria were Acinetobacter baumannii and Klebsiella pneumonia. All isolates were resistant to ampicillin-sulbactam; only 7.4% were sensitive togentamicin.Conclusion: Antibiotic use for neonatal sepsis in NICU in this study can be considered appropriate, suggesting proper implementation of antimicrobialguidelines. However, high rates of resistance to the first-line antibiotics for neonatal sepsis are concerning.
Uma ecologia de dragões
Authors: Chinellato Giovanna , Moraes Ricardo Gaiotto de
Published: December 2018

O dragão sobrevoa a humanidade desde a Idade Antiga, ele faz parte de mitos e histórias do Ocidente e Oriente, Antigo e Novo Mundos, rastejou pela cultura de sociedades que supostamente nunca se encontraram, da asteca à chinesa, da nórdica à hinduísta. Para Smith (1919, loc 1980), o dragão vem refletindo os medos e aspirações da humanidade por mais de cinquenta séculos, pois desenvolveu-se com a própria civilização. Este artigo analisa a representação de dragões notáveis de diversos períodos e observa que existe um paralelo entre o imaginário acerca dos dragões e a relação do homem com a natureza.
Hygienic assessment of handicapped adolescents vocational training conditions: problems and optimization opportunities
Authors: Eliseeva YuV , Voytovich AA , Milushkina OYu , Istomin AV , Eliseev YuYu
Published: December 2018

In a number of occupations, there is a shortage of labor force that can be filled with economically active part of the population, including people with disabilities (handicapped, HC). Unfortunately, observance of hygienic requirements in the context of HP adolescents vocational training has not been studied sufficiently: most scholars have researched only the conditions of teaching healthy adolescents. This study aimed to examine the HC adolescents vocational training conditions and develop measures to improve their working conditions with pathologies factored in. We examined adaptation potential, anxiety level, mental efficiency, sick rate and personal well-being assessment in HC adolescents (n = 120) aged 16–18, not impaired intellectually, studying sewing equipment operation, shoe repairs in the boarding scool. In the context of the study, we applied Smirnov hygiene criteria, Giessen Symptom Questionnaire, Spielberger's Test Anxiety Questionnaire, Sivkov scale, correction tables, Baevsky adaptation index. For the purposes of statistical analysis, we used parametric (Student t-test) and non- parametric (Mann–Whitney) criteria. The Spearman's correlation coefficient helped determine interrelationship of the studied parameters. We identified the following key adverse hygienic factors that have a significant impact on the students' health: intense character of labor performed, insufficient artificial lighting, noise level above the norm, high content of organic solvents and dust in the workshop's air. The timetable of the boarding school was also found to be inefficient. The results of this study allowed developing and introducing a software program to automatically compile the school's timetable with the aim to improve psychosomatic health of the students and halve the number of health-related complaints.
Evaluation of absorbed dose distribution in melanoma B16F10 during contrast enhanced radiotherapy with intratumoral administration of dose-enhancing agent
Authors: Lipengolts AA , Vorobyeva ES , Cherepanov AA , Abakumov MA , Abakumova TO , Smirnova AV , Finogenova YuA , Grigorieva EYu , Sheino IN , Kulakov VN
Published: December 2018

Contrast-enhanced radiotherapy (CERT) is a binary treatment modality in which the absorbed radiation dose is not only determined by the parameters of the external radiation source but also affected by the concentration of a dose-enhancing agent (DEA) in the studied object. In this work we assessed the distribution of the absorbed dose in a murine B16F10 melanoma injected with a single dose of an aqueous Bi-DTPA solution. The mice were exposed to a single fraction of X-ray irradiation for 28.5 min. In vivo measurements of DEA concentrations were done on a micro-CT scanner using the radiopacity values of malignant tissues from the obtained CT images. We found that the presence of DEA enhanced the absorbed dose more than twofold in 6% of the tumor volume; in 29% of the tumor volume the absorbed dose increased more than onefold. The tumor growth delay time calculated for our model was 0.76 days (we only accounted for the damage caused directly by radiation), whereas in our previous research study tumor growth delay was 10 days. This discrepancy may indicate that in the tumors exposed to contrast-enhanced radiotherapy growth delay results from both the damage directly caused by radiation and other antitumor mechanisms.
Buku Cerita Si Kancil dan Perilaku Meniru Siswa Taman Kanak-kanak
Authors: Syukria Syukria , Siregar Nina Siti Salmaniah
Published: December 2018

The purpose of this paper is to find out whether the storybook or the Kancil fairy tale influences the imitating behavior of the Sunggal 41 ABA 41 Kindergarten students and sees how storytellers are very influential in conveying the message content of a story. This research method uses descriptive, which is taking a problem or focusing on actual problems as they were at the time the research was conducted. The description in this study was to see the imitating behavior of the Sunggal 41 ABA Kindergarten students. The results of the study found that fairy tales or stories of the Kancil can enrich knowledge by recognizing various types of animals that are used as characters in a story or fairy tale or in increasing children's understanding of good and bad things. Children who tend to not be able to focus on one thing / object in a certain period of time are challenges and homework that the teacher must overcome when telling stories / storytelling. Short time and schedule of storytelling / storytelling activities obtained at school are not enough to-create-imitating-behaviors-of-children.
Evaluasi Kinerja Pegawai Bagian Program Kemitraan dan Bina Lingkungan pada PT. Perkebunan Nusantara III (Persero) Medan
Authors: Kadir Abdul
Published: December 2018

This study aims to determine the Employee Performance Evaluation of the Partnership and Community Development Program Section at PT. Perkebunan Nusantara III (Persero) Medan. Employee performance is the work that can be achieved by a person or group of people in an organization according to the authority and responsibility of each in order to realize the goals of the organization, which here will evaluate the performance of employees in the Partnership and Community Development Program at PT. Nusantara Nusantara III (Persero) Medan in 2016. Where many indicators can measure the performance of an employee. By looking at several indicators to determine performance success, namely productivity, service quality, responsiveness, responsibility and accountability, in this study using qualitative descriptive methods, the location of the study was conducted at the Office of the Partnership and Community Development Program at PT. Perkebunan Nusantara III (Persero) Medan, Data collection techniques are interviews, observation and documentation, it can be concluded that the Employee Performance Evaluation Section of the Partnership and Community Development Program at PT. Perkebunan Nusantara III (Persero) Medan is very good.
Inclusive classroom strategies for raising the achievement of students with dyslexia.
Authors: Stuart Alena , Yates Anne
Published: December 2018

The purpose of this research overview is to analyse literature on dyslexia and to identify and evaluate a range of inclusive classroom strategies which can influence the educational achievement of students with dyslexia. Tunmer and Greaney (2010) define dyslexia as “persistent learning difficulties” (p. 239) which present in “otherwise typically developing children, despite exposure to high quality, evidence-based literacy instruction and intervention” (p. 239). The difficulties arise due to a lack of phonemic awareness, key skills required to access literacy (2010). According to Mills (2018) there is no “quick fix or one prescribed intervention” (p. 38) to remediate dyslexia. This research overview provides an analysis of four studies followed by an evaluation of strategies suggested to improve learning outcomes for students with dyslexia. It concludes with key recommendations for inclusive practices which teachers could use to ensure students with dyslexia have the same opportunities to achieve as their peers.
HONEY, HE SHRUNK THE KIDS: SWIFT AND IRISH WRITING
Authors: KIBERD Declan
Published: December 2018

Honey, He Shrunk the Kids: Swift and Irish Writing. A study about Jonathan Swift as a founder of Anglo-Irish literature and of children’s literature, this paper delves into the “story of the repressed” and is an insight into the painful motivations that make the child-adult relationship an examination of human nature’s darker side of nature. This sub-genre considers the exploit of the defamiliarising effect in the tradition and types common in fairy tales of Gaelic Ireland and shows the Irish writer as a dissident and an upholder of tradition. The probability that his writing is the disclosure of any story’s potentiality is assumed by questing the welded joint of the relativity of all judgments, the extreme self-confidence of those who live at either extreme, the critique of unreasoning, tyranny and absence of rational justification of power systems.
Rezumat. Dragă, a micșorat copiii: Swift și literatura irlandeză. Un studiu despre Jonathan Swift, ca fondator al literaturii anglo-irlandeze si a celei pentru copii, această lucrare sondează “povestea celor reprimați” și discerne adevărata natură a motivațiilor dureroase care fac din relația copil-adult o examinare a părții întunecate a naturii umane. Aceasta variantă sub-generică vizează folosirea efectului defamiliarizării în tipologia și tradiția caracteristică basmelor Irlandei gaelice, și îl indică pe scriitorul irlandez ca deținător al tradiției și ca dizident. Probabilitatea ca scriitura sa să fie un mod de dezvăluire a potențialului oricărei povestiri este asumată de interogarea legăturii strânse dintre relativitatea oricărei forme de judecată, încrederea exagerată în sine a acelora care trăiesc în orice mod extrem de viață, critica lipsei de judecată, a tiraniei și a absenței oricărei justificări a unor astfel de sisteme de putere.
Cuvinte cheie: Jonathan Swift, literatura irlandeză, literatura pentru copii, narațiuni fantastice, povestea gaelică, elita puterii, critica lipsei de judecată.
KEVIN BARRY’S ATLANTIC DRIFT
Authors: ALLEN Nicholas
Published: December 2018

Kevin Barry’s Atlantic Drift. Kevin Barry is a contemporary Irish novelist, short-story writer, dramatist and publisher whose work is set on the island's coastal fringes. This essay is a reading of some stories from There are Little Kingdoms and of his first novel, The City of Bohane. In tracing the importance of liquid and maritime imagery it suggests the importance of a sea-side perspective in his writing, and situates this perspective in wider conversations about ideas of islands and archipelagos.
Rezumat. Deriva atlantică a lui Kevin Barry. Kevin Barry este un romancier, nuvelist, dramaturg și publicist contemporan irlandez, a cărui operă este plasată în spațiul de  coastă al insulei. Eseul de față este o lectură a unora dintre povestirile din There are Little Kingdoms și al primului său roman, The City of Bohane. Subliniind importanța imaginilor acvatice și maritime, se sugerează importanța unei perspective maritime în scriitura acestuia, plasându-se această perspectivă într-o discuție mai largă despre insule și arhipelaguri.
Cuvinte cheie: coastă, arhipelag, apă, estuar, mareic, insulă
EMERGING STORIES: THE (AUTO)BIOGRAPHICAL GAME
Authors: BERCE Sanda
Published: December 2018

Emerging Stories: The (Auto)biographical Game. The paper is an inquiry into “the game with the (auto)biographical”, as part of the Irish modern and contemporary experimental and innovative prose. The special status of these writings emerges from the self-representational impulse and defines a novel typology about temporality and time-control by the twin action of imagination and memory. The paper refers to the memoir as a complex merging of fiction and non-fiction in an interpretive field where the borderline between the historically verifiable facts and the fictive (constructed) events is unveiled. The Irish contemporary “memoirs”, containing a mixture of analysis and an (auto)biographical game, are viable responses to the emergence of the new and unfamiliar Ireland.
Rezumat. Istorii emergente: jocul (auto)biografic. Lucrarea este o investigație asupra “jocului cu (auto)biograficul”, ca element al prozei irlandeze moderne și contemporane, de factură experimentală, inovatoare. Statutul special al acestui tip de proză își are sursa într-un impuls de auto-reprezentare și definește o tipologie romanescă ce are drept principal scop a controla timpul printr-o acțiune îngemănată a imaginației și a memoriei. Lucrarea se referă la memorii ca la o formă complexă de combinare a elementului ficțional și a celui non-ficțional, într-un câmp interpretativ în care zona de delimitare dintre faptele verificabile istoricește și evenimentele fictive (construite) este revelată. Conținând o mixtură de analiză și “joc cu (auto)biograficul,” memoriile din literatura irlandeză contemporană sunt răspunsuri viabile la apariția unei Irlande noi și nefamiliare.
Cuvinte cheie: experimental, jocul (auto)biografic, memorii, narațiuni biografice, câmpul interpretării, impulsul autoreprezentării.
CHECK IMPULSE: TRAVERSING HADES
Authors: MOLDOVAN Rareș
Published: December 2018

Check Impulse: Traversing Hades. The paper considers the “Hades” episode in Joyce’s Ulysses with a view towards the concepts of mobility, urban space and impulse interwoven therein. A traverse of the city as pre-modern and modern arrangement of space and social dynamics, from street to cemetery the chapter gathers the various meanings of social mobility, together with their socialised impulses and checks. Outer mobility and inner impulsivity are analysed in their interrelation in macro- and micro-contexts.
Rezumat. Verifică impulsul: traversând Hades. Articolul discută episodul “Hades” din Ulise de James Joyce, din perspectiva conceptelor de mobilitate, spațiu urban și impuls, care se întrepătrund în text. O traversare a orașului ca aranjament pre-modern și modern al spațiului și dinamicii sociale, din stradă la cimitir capitolul înmănunchează sensurile varii ale mobilității sociale, împreună cu impulsurile și obstacolele lor socializate. Mobilitatea exterioară și impulsivitatea interioară sunt analizate în interrelația lor în macro- și micro-contexte.
Cuvinte cheie: James Joyce, Ulise, spațiu urban, mobilitate, impuls socializat
WHEN STORYTELLING BECOMES HERITAGE
Authors: RADU Adrian
Published: December 2018

When Storytelling Becomes Heritage. Ireland is a country with an almost unique experience in storytelling. The stories represent a treasury of what for centuries used to be the oral tradition of the Celts, a people whose civilisation dawned in Europe but who found in Ireland a sheltered place where their original culture could be preserved. These tales take us to a fabulous and fascinating world, where reality blends with fantasy with unequalled lack of any restraint and where time, as we conceive it, practically does not count. Their setting is both ancient Ireland and the mythical world of the Sídhe, the enchanted Otherworld of the faeries (Gantz 1981, 2). It is the aim of this article to concentrate on a few of such stories or tales considered more representative and examine how they became the essence of the inherited Irish spirit and were transmitted from generation to generation and constituted what is now called Irishness.
Rezumat. Când arta povestirii devine patrimoniu. Irlanda e o țară cu o experiență aproape unică a povestitului. Poveștile reprezintă un tezaur a ceea ce a fost vreme de secole tradiția orală a celților, un popor a cărui civilizație își are originile în Europa, dar care a găsit în Irlanda un spațiu ocrotit, în care cultura lor a putut fi păstrată. Aceste povești ne conduc într-o lume fabuloasă și fascinantă, în care realitatea se îngemănează cu fantezia fără limite, și în care timpul așa cum îl concepem noi de fapt nu contează. Acest tărâm este în același timp Irlanda antică și lumea mitică a așa-numitelor Sídhe, fermecata Lume de Dincolo a zânelor (Gantz, 2). Articolului de față intenționează să se concentreze asupra câtorva dintre aceste povești dintre cele considerate mai representative și să examineze cum au devenit esența spiritului irlandez, transmise din generație în generație, constituind ceea ce se numește azi specificul irlandez.
Cuvinte cheie: Tuatha Dé Danaan, Ulster, Cú Chulainn, Macha, Finn MacCool, Fianna, Oisín, dinnsheanchas, imram, echtra, buile, Sweeney
FEASTING ON THE TEXT: THE “ULYSSES” CENTENARY IN ROMANIAN PERIODICALS
Authors: PĂCURAR Elena
Published: December 2018

Feasting on the Text: the “Ulysses” Centenary in Romanian Periodicals. The aim of this paper is to revisit a selection of the Romanian periodical issues dedicated to James Joyce’s fiction up until the 1980s. Our investigation of the main themes and topics published before and after the year 1982 reveals an alignment with an already established shift of perception in Joycean studies: the author is glorified as an Irish and/or Irish-European modernist writer whose assignment to a specific, local culture is the pre-condition of his modernity and innovative style.
Rezumat. Ospățul textual: centenarul James Joyce în publicistica românească. Lucrarea operează o selecție a câtorva reviste și ziare românești care au dedicat spațiu editorial ficțiunii scriitorului James Joyce. Analiza noastră, care face referire inclusiv la câteva dintre temele abordate de aceste reviste în jurul centenarului Joyce, reflectă o schimbare de percepție în studiile joyceene în general. Această modificare vizează receptarea lui Joyce ca scriitor irlandez și/sau irlandezo-european a cărui apartenență la o cultură specifică este temelia modernității și a inovației sale stilistice.
Cuvinte-cheie: receptare, traducere, periodice românești, modernism irlandez, canonul european
A VISION OF A VISION
Authors: OLTEAN-CÎMPEAN Alexandru
Published: December 2018

A Vision of a Vision. When readers and critics look upon the life and works of William Butler Yeats, they most often (and justifiably) focus on his poetry. Nevertheless, an interesting aspect to look into concerns Yeats’ personal philosophy on life and art. It is a perspective that already begins to take shape beginning with his first collection of poetry and which is eventually set to paper in the aptly named A Vision. One of the few scholars to analyze this grandiose text is Harold Bloom, who sees it as “a beautiful book, a considerable if flawed major poem” (Bloom 1970, 210). Flawed or not, A Vision remains a fascinating illustration of the poet’s belief system and the present article explores how this system is constructed.
Rezumat. Viziunea din “A Vision”. Când cititori ori critici își îndreaptă atenția asupra operei lui William Butler Yeats, de cele mai multe ori se axează (justificabil) pe poezia sa. Cu toate acestea, un aspect interesant care merită cercetat ține de filosofia personală a lui Yeats în ceea ce privește viața și arta. Este o perspectivă care începe să capete formă începând cu prima sa colecție de poezii și care este în final pusă pe hârtie în opera numită cu iscusință A Vision (O Viziune). Printre puținii cercetători care analizează acest text grandios este Harold Bloom, care îl vede ca fiind „o carte minunată, un poem major considerabil deși imperfect” (Bloom 1970, 210 traducerea mea). Imperfect sau nu, A Vision rămâne o ilustrare fascinantă a sistemului de credințe a poetului, iar prezentul articol explorează modul în care este construit acest sistem.
Cuvinte cheie: A Vision, William Butler Yeats, sistem de credințe
SHIFTING PERSPECTIVES: LEOPOLD BLOOM, HOSPITALITY, AND THE OTHER IN JAMES JOYCE’S “ULYSSES”
Authors: MELNIC Diana
Published: December 2018

Shifting Perspectives: Leopold Bloom, Hospitality, and the other in James Joyce’s “Ulysses”. The present paper interprets the character of Leopold Bloom in light of his incorporation of the ethical necessity to “see ourselves as others see us”, as well as the meaning acquired by the character when read against the context of the Great War. We propose that Bloom the redeemer, as he is portrayed on several occasions throughout the day, is not a single Messianic figure, but rather a type of human being with a distinctive attitude to the experience of the Other. The protagonist, himself an exile, is perpetually prone to shed his own point of view in favour of that of alterity, in other words, to see the world as others might see it. His acts of kindness, his generous, gentle nature, and his interactions with Stephen and Molly can all be viewed, as I will argue, as consequences of this almost in-built shift of perspective.
Rezumat. Schimb de Perspectivă: Despre Leopold Bloom, Ospitalitate și Alteritate în “Ulise”. Lucrarea de față propune o interpretare a personajului Leopold Bloom plecând de la felul în care acesta reiterează versul lui Robert Burns, „să ne vedem cum ne văd alții,” și având în vedere faptul că James Joyce scrie Ulise în timpul primului război mondial. În acest sens, Bloom salvatorul, așa cum el este descris pe parcursul romanului, nu este propriu-zis o figură mesianică, ci, mai degrabă, exponentul unei tipologii umane cu a atitudine deosebită față de experiența alterității. El însuși exilat din orice comunitate, protagonistul tinde întotdeauna să renunțe la propriul punct de vedere în favoarea Celuilalt. Cu alte cuvinte, Bloom vede lumea așa cum o văd alții.
Cuvinte cheie: Leopold Bloom, perspectivă, ospitalitate, iubire, etica alterității, Levinas, Derrida.
JAMES JOYCE’S “ULYSSES”: READING THE SELF IN THE BODY
Authors: MELNIC Vlad
Published: December 2018

James Joyce’s “Ulysses”: Reading the Self in the Body. Throughout this paper, my primary contention is that, as a book, Ulysses is a body of potentialities meant to help readers consubstantiate with their selves, with a special dedication for the Irish audience of the 1900s in particular. I suggest, in other words, that from a post-humanist perspective, the novel’s most metempsychotic feature remains its ability to guide readers out of their self-legitimising narratives and into the seat of their consciousness, the individual body. As the reader suspends their personal existence to engage with the body of the book, the latter helps deliver them into life-actual, all the while internalising a story unravelling its own textual cessation. This perspective on Ulysses involves re-tracing the human body within each narrative level, and the changes it undergoes through the novel’s embeddedness.
Rezumat. “Ulise” de James Joyce: Regăsirea Sinelui în Trup. Pe parcursul lucrării de față, teza principală este că romanul Ulise reprezintă o totalitate de entelehii menite să ghideze cititorul spre consubstanţialitate cu sinele, vizând, în mod special, publicul irlandez de la început de secol al XX-lea. Lucrarea evidenţiază cel mai metempsihotic aspect ale cărţii, anume abilitatea sa de a-l ghida pe cititor dincolo de povestirile auto-justificatoare ale sinelui şi spre originea conştiinţei umane, anume trupul individual. Astfel, corpul lui Ulise are menirea de a izbăvi cititorul întru faptul concret de a fi, chiar în timp ce acesta îşi suspendă existenţa individuală pentru actul citirii. O astfel de perspectivă asupra romanului necesită re-găsirea corpului uman în universul acţiunii propriu-zise, apoi continuând cu modul în care acesta este transformat de încadrările care se suprapun şi/sau intercalează cu cel dintâi.
Cuvinte cheie: Ulise, uzul corpurilor, zonă de non-conștiință, naratologie corporală, Agamben, Damasio, Punday.
POSTHUMAN ELEMENTS IN SAMUEL BECKETT’S “KRAPP’S LAST TAPE”
Authors: DUPU Diana Cosmina
Published: December 2018

Posthuman Elements in Samuel Beckett’s “Krapp’s Last Tape”. The present paper aims to offer insight regarding the post-anthropocentric elements present in one of Samuel Beckett’s most innovative plays, Krapp’s Last Tape. In order to support my premise, I wrote a comprehensive theoretical outline of posthumanism, taking into account aspects such as the adaptation of the brain to new technologies and the influence they exert, the appearance and usage of prosthetics, symbiotic relationships and the interconnectedness between body, mind and environment. I then proceeded to offer my own interpretation of the target text, focusing on Beckett’s recurrent tendency to represent the body as an aged, decaying and fallible organic vessel and relevant human-machine symbiosis. Humanity’s centrality is deconstructed by focalising on its subservience to suffering.
Rezumat. Elemente postumane în piesa “Ultima Bandă a lui Krapp” de Samuel Beckett. Axată pe una dintre cele mai inovatoare piese din palmaresul Beckettian, lucrarea de față indică prezența elementelor post-antropocentrice în Ultima Bandă a lui Krapp. Pentru a demonstra validitatea acestei premise, am început prin a concepe un synopsis al teoriei postumaniste, axându-mă pe aspecte cum ar fi adaptarea creierului la noile tehnologii și influența exercitată de acestea, apariția și utilizarea elementelor prostetice, relațiile simbiotice și interconectivitatea dintre corp, minte și mediu. Interpretarea textului a luat în considerare tendința recurentă a lui Beckett de a reprezenta corpul uman ca un vehicul organic failibil, în descompunere, dar și simbioza dintre om și mașinărie. Piesa arată în repetate rânduri că omul este supus suferinței, deconstruind astfel poziția centrală a umanității.
Cuvinte cheie: Samuel Beckett, “Ultima Bandă a lui Krapp”, Postumanism, minți post-corporale, simbioză tehnologică, memorie, deconstrucție, mortalitate
Mare crisium: complots y conspiraciones como mecanismo político para el relevo de cúpulas en los regímenes comunistas
Authors: Witker Barra Ivan Leon
Published: December 2018

El trabajo analiza CUBA, la Republica Democratica Alemana y China
UPAYA REHABILITASI EKS PEKERJA SEKS KOMERSIAL (PSK) DI PANTI SOSIAL KARYA WANITA (PSKW) ANDAM DEWI SOLOK
Authors: Saefulloh Ahmad , Nofriza Nofriza
Published: December 2018

This study aims to see the rehabilitation efforts of former Sex Workers Commercial (PSK) in Panti Sosial Karya Wanita (PSKW) Andam Dewi Solok. The large number of sex workers becomes a serious problem that must be followed up immediately. The Crowd raids prostitution reported in the media into the spotlight of the world of education in instilling moral education to learners. This is the importance of recognizing the negative impacts. To avoid the proliferation of the practice of prostitution is necessary to preventive and rehabilitative efforts against the perpetrators of prostitution practices that netted raids. This study aims to provide a form of preventive and rehabilitative efforts for the "eks PSK" who were caught raids in social institutions as well as to the general public. This research is a qualitative descriptive study. Data collection by observation method, direct interview and documentation. Techniques used in data analysis are data display, data reduction and conclusion. The data validity technique uses source triangulation. The results showed that: 1) preventive efforts that can be done include the formation of wirid adolescents and regular weekly recitation, 2) submission of grants through grant channeling institutions. While rehabilitative efforts include religious programs, skills and crafts as well as long-term assistance.
Assessment of caregiver burden and associations with psychosocial function, veterinary service use, and factors related to treatment plan adherence among owners of dogs and cats
Authors: Spitznagel Mary Beth , Cox Melanie D. , Jacobson Dana M. , Albers Angela L. , Carlson Mark D.
Published: December 2018

OBJECTIVE To investigate caregiver burden and its potential associations with psychosocial function and veterinary service use among dog and cat owners and with factors related to treatment plan adherence among owners of animals with chronic or terminal disease.

DESIGN Cross-sectional, observational study.

SAMPLE 124 clients of a small animal hospital.

PROCEDURES Study participants were recruited by email. Owners of sick animals were blindly matched with owners of healthy animals (62/group) by age, gender, and companion animal species. Respondents completed electronic questionnaires related to demographics and previously described measures of caregiver burden, psychosocial function, and treatment plan adherence. Veterinary medical records were reviewed to verify animal health status and assess veterinary service use (billable and nonbillable contacts with veterinary staff) in the 12 months prior to study enrollment. Variables were tested for association by statistical methods.

RESULTS Questionnaire scores reflected greater caregiver burden; greater symptoms of depression, anxiety, and stress; and poorer quality of life for respondents with sick animals than for respondents with healthy animals. Greater caregiver burden was associated with scores reflecting poorer psychosocial function and with greater veterinary service use. The number of nonbillable, but not billable, contacts was greater for respondents with high caregiver burden than for those without this finding. Treatment plan factors associated with greater caregiver burden included changes in routine because of the animal's condition and perception that following new rules and routines for management of the condition was challenging.

CONCLUSIONS AND CLINICAL RELEVANCE Awareness of potential caregiver burden and psychosocial distress in clients with sick companion animals may help veterinarians identify opportunities for an empathic response. Future research should assess directionality of the relationship between these factors.
Quantum chemical study of electron structure and charge transport properties of symmetric acenequinones
Authors: Cagardová Denisa , Michalík Martin , Poliak Peter , Lukeš Vladimír
Published: December 2018

A systematic theoretical study using density functional theory is presented to estimate the structural, electronic, and charge-transfer characteristics of a symmetric fluorination of acenequinones outer rings. The change in aromaticity of model derivatives was described by different types of aromaticity indices. By considering a hopping mechanism and using the Marcus theory in combination with the Einstein-Smoluchowski relation, electronic drift mobilities were predicted for selected dimer configurations obtained from X-ray structures of anthraquinone, 6,13-pentacenequinone and its octafluorinated derivatives. The analysis of obtained data showed that the fluorination of the outer rings of acenequinones can lower the energy of the lowest unoccupied molecular orbital to the range from −3.0 to −4.0 eV, i.e. typical for organic n-type semiconducting materials. Finally, potential electric semiconductivity of available X-ray structures relating to drift mobilities was discussed.
The design and NMR structure determination of yttrium-oligopeptide tags for recombinant proteins and antibodies
Authors: Múdra Marcela , Breza Martin , Lintnerová Lucia , Filo Juraj , Bauer Jacob
Published: December 2018

A strategy for the design of new yttrium(III) tags consisting of sequences of naturally occurring amino acids is described. These tags are 4–6 amino acids in length and consist of aspartic and glutamic acids. The use of natural amino acids would allow these oligopeptides to be incorporated into recombinant proteins at the DNA level, enabling the protein to be Y(III)-labelled after protein isolation. This allows a radionuclide or heavy atom to be associated with the protein without the necessity of further synthetic modification. Suitable peptides able to chelate Y(III) in stable complexes were designed based on quantum-chemical calculations. The stability of complexes formed by these peptides was tested by isothermal titration calorimetry, giving dissociation constants in the micromolar range. The likely structure of the most tightly bound complex was inferred from a combination of NMR experiments and quantum-chemical calculations. This structure will serve as the basis for future optimizations.
Relation of Serum 25(OH)-Vitamin D to Fat Mass and Lean Mass, Bone Mineral Content and Body Composition in Adults – a DXA-Based Study
Authors: Nikolova M. G. , Penkov A. B. , Boyanov M. A.
Published: December 2018

Obesity has been linked with vitamin D deficiency in a number of cross-sectional studies, reviews and meta-analyses. The aim of the present study was to assess the correlations of plasma 25(OH) vitamin D levels with indices of body composition examined by DXA with an emphasis on lean and bone mass as well as on indices such as android/gynoid fat, appendicular lean mass, fat-mass indexes (FMI) and fat-free mass indexes (FFMI). 62 adult subjects consented to participate – 27 men (43.5%) and 35 women (56.5%). Their mean age was 45.3 ± 9.5 years. Fan-beam dual-energy X-ray (DXA) body composition analysis was performed on a Lunar Prodigy Pro bone densitometer with software version 12.30. Vitamin D was measured by electro-hemi-luminescent detection as 25(OH) D Total (ECLIA, Elecsys 2010 analyzer, Roche Diagnostics). Statistical analyses were done using the SPSS 23.0 statistical package. The serum 25(OH)D level was correlated significantly only to the whole body bone mineral content, the appendicular lean mass index (ALMI) and the ALM-to-BMI index, underlining a predominant role for lean and fat-free mass. Vitamin D showed a very weak correlation to % Body Fat and the Fat Mass Index (FMI) in men only. Moreover, the multiple regression equation including the associated parameters could explain only 7% of the variation in the serum 25(OH) D levels. Our conclusion was, that there are differences in the associations of the vitamin D levels with the different body composition indices, but these associations are generally very weak and therefore – negligible.
Aesthetic Reconstruction of the Hairline with Local Tissue
Authors: Yordanov Y. P. , Shef A. , Lasso J. M.
Published: December 2018

Hairline is a crucial landmark in facial aesthetics. Its restoration in terms of position, continuity and hair growth is of a paramount importance in facial plastic aesthetic and reconstructive surgery. The purpose of the paper is to demonstrate the effectiveness of using local tissue only in the restoration of skin and soft tissue defects affecting the hair-line. A brief retrospective analysis of clinical cases with defects engaging the hairline was made. The majority of the patients (20 out of 22) were operated because of skin lesions of different entities. In 7 of the cases the direct closure technique was applied as a surgical tool for hairline restoration and in 15 of them rotational flaps were the best reconstructive option. A special emphasis is put on the defect size in regards of choosing the right surgical technique for defect closure in order to achieve the best aesthetic outcome in the hairline restoration.
External Congenital Lacrimal Sac Fistula: А Case Report
Authors: Valcheva Kr. , Krivoshiiska E. , Murgova Sn.
Published: December 2018

Congenital lacrimal fistula is a developmental abnormality. This is a case of a patient with an external congenital lacrimal sac fistula. Surgical treatment was used to correct the condition. Immediate postoperative results were seen. To present a case of a patient with an external congenital lacrimal sac fistula, in which surgical treatment was applied and immediate postoperative results with a good outcome were seen. A 3-year-old boy with an external congenital lacrimal sac fistula presented to our clinic. The skin orifice was observed on the left eye in a typical place – located in the inferomedial aspect of the medial canthal angle. The patient was treated in the at the Eye clinic, at university hospital “Dr. Georgi Stranski” – Pleven, Bulgaria. He underwent a surgical procedure – simple fistula excision (closed fistula excision). The surgical technique was a successful closed fistula excision. In the immediate postoperative period there were no complications such as infection, recurrence or worsening of the epiphora, poor cosmetic results, bleeding or damage to the lid structures or nose. The prognosis for patients with congenital lacrimal fistulas is quite good. Many are asymptomatic and those who have symptomatic epiphora or mucoid discharge can be successfully treated by surgery. Several surgical options exist – closed fistula excision, dacryocystorhinostomy (DCR) with fistula excision and fistula excision with nasolacrimal intubation. Symptomatic congenital lacrimal sac fistulas can be treated successfully with excision alone.
The effect of a water dam on Lake Powidzkie and its vicinity
Authors: Nowak Bogumił Michał , Ptak Mariusz
Published: December 2018

The paper presents an attempt to assess the effect of damming of lakes on water resources, based on the example of Lake Powidzkie (Central Poland) and its catchment. The region in which the analysed object is located has the greatest water deficits in Poland. The co-occurrence of unfavourable natural and anthropogenic factors contributed to a considerable reduction in the water resources retained in the lake. Particularly low water levels were recorded in the 1990s and in the first decade of the 21st century. The situation was not improved by a water dam constructed on the out-flow from the lake in the 1960s, due, among other things, to neglect in its exploitation. With regard to the modernisation of the dam in 2010 and the favourable hydrological situation in the winter of 2011, it was possible to retain the excess water and substantially reduce its outflow. The restoration of the lost water resources, and the hydrological benefits of this were still observable several years later. Problems related to water deficits are becoming increasingly common in many regions of the world. One solution to mitigate such a situation may be, among others, to dam natural lakes. This is simpler, cheaper, and less invasive for the environment than the construction of new water reservoirs.
Water temperature in the lakes of Northern Poland during the bathing season
Authors: Skowron Rajmund
Published: December 2018

The study presents characteristics of the bathing season on the basis of stationary daily measurements of surface water temperature in the lakes in the period 1971-2015 conducted by the Institute of Meteorology and Water Management. These measurements were taken in the littoral zone (from bridges) of 28 lakes at 7:00 (6:00 GMT). In order to determine representativeness of these measurements, the author also documents the comparison of water temperature with its values at various points of the lake and its daily course. Stationary surface water temperature measurements provided the basis for the characteristics of the average, the earliest and the latest dates of the beginning and end of the bathing seasons, their duration and mean water temperatures in the summer months. Hence, a new parameter (tsum) is introduced to define the mean surface water temperature for the summer months (June, July and August), and compare water temperature in lakes over a larger area (the Baltic Sea catchment area). The most favorable conditions for bathing in Polish lakes are found in the western part of the Wielkopolskie Lakeland (lakelands: Łagowskie, Poznańskie, Sławskie) from the beginning of July to the end of August, when the surface water temperature in lakes generally exceeds 18°C. Furthermore, the best conditions for bathing in the water are from 10:00 to 18:00. When choosing a place to relax, holidaymakers should also consider bathing locations, infrastructure and safety conditions.
Analysis of air mass back trajectories with present and historical volcanic activity and anthropogenic compounds to infer pollution sources in the South Shetland Islands (Antarctica)
Authors: Szumińska Danuta , Czapiewski Sebastian , Szopińska Małgorzata , Polkowska Żaneta
Published: December 2018

This work analyses atmospheric transport of natural and anthropogenic pollution to the South Shetland Islands (SSI), with particular reference to the period September 2015 – August 2017. Based on data from the Global Volcanism Program database and air mass back trajectories calculated using the HySPLIT model, it was found that it is possible that in the analysed period volcanic pollution was supplied via long-range transport from South America, and from the South Sandwich Islands. Air masses flowed in over the South Shetland Islands from the South America region relatively frequently – 226 times during the study period, which suggests the additional possibility of anthropogenic pollution being supplied by this means. In certain cases the trajectories also indicated the possibility of atmospheric transport from the New Zealand region, and even from the south-eastern coast of Australia. The analysis of the obtained results is compared against the background of research by other authors. This is done to indicate that research into the origin of chemical compounds in the Antarctic environment should take into account the possible influx of pollutants from remote areas during the sampling period, as well as the possible reemission of compounds accumulated in snow and ice.
Accommodating business travellers: The organisation and spaces of serviced apartments in Cape Town, South Africa
Authors: Greenberg Desire , Rogerson Jayne M.
Published: December 2018

In recent years several new forms of lodging have developed as alternatives to the hotel. For business travellers the serviced apartment has emerged as a new phenomenon. Within extant accommodation scholarship the service apartment sector has attracted minimal international attention either from tourism or property researchers. This paper analyses the development and character of service apartments in one of South Africa’s major business tourism destinations, the city of Cape Town. It is disclosed that serviced apartments are clustered around different business nodes in the city and spatially differentiated in terms of serving distinctive business traveller markets.
Nature-based tourism operators’ perceptions and adaptation to climate change in Hwange National Park, Zimbabwe
Authors: Mushawemhuka William , Rogerson Jayne M. , Saarinen Jarkko
Published: December 2018

Climate and weather are important resources for tourism. In particular, nature-based tourism activities and operations are largely dependent on and affected by environmental conditions and changes. Due to the significant socio-economic role of the nature-based tourism and the tourism industry, in general, in the region of southern Africa it is important to understand the dynamics between the industry and climate change. A key aspect of this understanding are perceptions and adaptation preparedness of tourism operators towards the estimated impact of climate change. There is a dearth of empirical studies on climate change perceptions and adaptation in nature-based tourism operations across southern Africa and specifically from Zimbabwe. This research gap is addressed in this article which provides an exploratory analysis of the nature of climate change adaptation practices occurring in southern Africa using evidence from Hwange National Park, Zimbabwe.