bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Serum Iron and Ferritin Levels as Inflammatory Markers in Calves with Bovine Respiratory Disease Complex
Authors: Değirmençay Şükrü , Kirbaş Akın , Aydin Hakan , Aydin Ömer , Aktaş M. Sinan , Kaman Ramazan
Published: April 2022

Iron and ferritin have been used in human medicine for years to reveal the presence of inflammation. However, studies evaluating these parameters, especially in respiratory system diseases, are quite rare in veterinary medicine. We aimed to test the usability of serum Fe and Fe-related parameters [total iron-binding capacity (TIBC), unsaturated iron-binding capacity (UIBC) and transferrin saturation (TS) levels] as inflammatory and diagnostic biomarkers in calves with bovine respiratory disease complex (BRDC). To mark inflammation, some selected acute-phase proteins including serum ferritin and transferrin levels were measured because of their close relationship with iron metabolism. The material of this study consisted of 15 calves, aged 1-3 months with BRDC (Group I) and 10 healthy calves aged 1-3 months (Group II) based on the presence of respiratory clinical findings. Serum Fe, TIBC and TS levels were low and ferritin levels were high in Group I (P ≤ 0.001). The BRDC group was separated into two subgroups based on PCR results, namely Virus+ (n=9) and Virus- (n=6). The calves in the Virus+ group had significantly lower levels of Fe (P=0.001) and significantly higher values of ferritin (P=0.002), compared to the healthy group. On the basis of inter-group comparison and ROC analysis, we concluded that Fe (primarily), ferritin, TIBC and TS levels can be used as inflammatory biomarkers and possible diagnostic markers in the BRDC as useful, practical, inexpensive substitutes. As a suggestion, these parameters which are believed to play a role in the pathogenesis of the disease, can be used as potential prognostic biomarkers in studies involving treatment.
Improvement of Hygiene Practices and Milk Hygiene Due to Systematic Implementation of Preventive and Corrective Measures
Authors: Mihajlović Ljubiša , Cincović Marko , Nakov Dimitar , Stanković Branislav , Miočinović Jelena , Hristov Slavča
Published: April 2022

The Total Bacterial Count (TBC) and the Somatic Cells Count (SCC) in the milk are important indicators of its hygiene and quality. Hygienic conditions in barns, milking procedures, udder hygiene before, during and after milking, milking machine hygiene, as well as milk cooling procedures immediately after milking, have direct or indirect influences on milk hygiene indicators. Poor results of milk hygiene quality, when it comes to SCC and TBC, which are often seen in dairy cattle farms in our country, indicate numerous omissions before and during milking. To determine the possibility of improving milk hygiene quality, training of extension service professionals and farmers was conducted, corrective and preventive measures were determined and the achieved state was monitored on 128 dairy farms where SCC and TBC were observed at regular monthly intervals for 6 months. The results showed a continuous statistically very significant improvement in hygienic conditions in barns, milking procedures, udder hygiene before, during and after milking, milking machine hygiene, as well as milk cooling procedures. This has contributed to a statistically very significant improvement in the hygienic quality of milk, both in SCC and TBC indicators, continuously from month to month, with a visible improvement at the end related to the beginning of the study period. At the begining and the end of survey 19.7% and 50.0% of milk samples belong to 1st class of milk quality, respectively, indicating a significant improvement after implementation of corrective measurements.
Purulent Renal Papillitis Due to Streptococcus Infantarius Subsp. Infantarius in a Horse
Authors: Eroksuz Yesari , Otlu Baris , Yerlikaya Zeynep , Tanriverdi Elif Seren , Incili Canan Akdeniz , Karabulut Burak , Timurkan Mehmet Ozkan , Eroksuz Hatice
Published: April 2022

A 6-year-old, male Arabian crossbred horse was necropsied after a 10 day history of loss of appetite, debility and weight loss. Gross and histologic examination was consistent with purulent papillitis due to Streptococcus infantarius subsp. infantarius. The isolate was sensitive to all the antibiotics tested.
NiO/CuO/TiO2 Ternary Composites: Development, Physicochemical Characterization and Photocatalytic Degradation Study Over Reactive Orange 30 Solutions Under Solar Light Irradiation
Authors: Muthamilarasu A. , Sivakumar S. , Divya G. , Sivakumar M. , Sakthi D.
Published: April 2022

The photocatalytic degradation and mineralization of Reactive Orange 30 on NiO/CuO/TiO2 ternary composites have been studied using solar light irradiation. The NiO/CuO/TiO2 ternary composites were prepared by producing ethanolic dispersions containing varied amounts of NiO and CuO/TiO2 (3wt% to 15wt.%), followed by annealing at 300 °C. SEM, UV- Vis DRS, PL, XRD and FTIR analysis have been used to characterize the unary (parent photocatalysts), binary and ternary composites. Under solar light irradiation, NiO/CuO/TiO2 ternary composites exhibited an excellent photocatalytic activity in degradation of reactive orange 30 in aqueous solution, whereas the NiO/TiO2, CuO/TiO2 and bare photocatalyst such as NiO, CuO, TiO2 showed lower activities. It was deduced that the remarkable visible-light absorption phenomenon and band gap reduction of the NiO/CuO/TiO2 ternary composites taking place. It paves way for the photogenerated electron transfer between CB of the NiO, CuO, TiO2 semiconductors and also holes shifting between VB of above mentioned materials. The NiO/CuO/TiO2 ternary composite shows good photostability and the photocatalyst retains 94% of its initial activity in the seventh cycle, respectively.
Strength and Durability of Cement Stabilized Expansive Soil Amended with Sugarcane Press Mud
Authors: James Jijo , Selvam Akilan Gunaselvi , Annamalai Krishna Khumaar , Marimuthu Vishal , Srinivasan Vishnu Varadhan , Kolamurugan Sooraj
Published: April 2022

The present investigation delved into the performance of cement stabilized soil amended with sugarcane press mud (PM), an organic waste residue from the sugar industry. An expansive soil was stabilized using 3% and 8% ordinary Portland cement (OPC) and modified with 1%, 3% and 5% PM. Cylindrical samples of dimensions 38 mm diameter and 76 mm height were cast and cured for 7, 14 and 21 days for all combinations considered. After the designated curing periods, the specimens were strained axially until failure to determine the strength of the samples. Samples were also subjected to alternate cycles of wetting and drying and the resistance to loss in weight was determined. The results of the investigation revealed that PM can be considered as a strength accelerator due to enhancement in early strength of the samples at 7 days of curing but beneficial strength gain could not be sustained over extended curing periods considered. However, 1% and 3% PM modified specimens were more resistant to weight loss when compared to pure cement stabilized specimens. Based on the results of the investigation, PM can be considered as a potential auxiliary additive to cement stabilized soil for improving the durability performance of the soil.
Shrinkage and Absorption of Sand Concrete Containing Marble Waste Powder
Authors: Djebien Rachid , Abbas Yassine , Bouabaz Amel , Ziada Yasser Nacereddine
Published: April 2022

In the context of growing scarcity of natural resources, the high demand of aggregates and the difficulties to open new quarries, several studies were carried out to study the possibility of reuse of waste and industrial by-products to replace traditional materials which would run out, replace materials when transport distances increase to reduce construction costs and protect the environment. This experimental study aims to investigate the effect of marble waste used as powder on the shrinkage and absorption of sand concrete in order to reuse it in the production of sand concrete. To achieve this goal, several sand concrete mixtures containing different substitutions rates of marble powder (4, 8 and 12%), and different Water / Cement ratio (0.71, 0.74, 0.77) were produced. Then, the evolution of the shrinkage and absorption values of sand concrete mixtures was studied. The obtained results showed that marble waste powder plays a positive role in reducing of shrinkage and absorption values of sand concrete and lead to the production of eco-friendly sand concrete.
The Determinants of the Existing Conditions on the Functional and Spatial Development of Rural Areas
Authors: Borucińska-Bieńkowska Hanna
Published: April 2022

The article discusses selected issues regarding the influence of ecophysiographic and cultural- historical determinants on functional-spatial development of rural areas. Ecological, economic and social processes the have been past few decades are examined in the context of the development of local self-governments and the rise of free market economy after Poland’s socio-economic transformation. The process of intensive rural urbanization occurs especially in areas within the impact zone of big cities. It is caused by, i.a., human migration into rural areas and development of areas of business activation. The abovementioned tendencies that occur in the ecological, economic and social context have a significant impact on functional-spatial development. Expansion of housing developments and, in effect, expansion and development of necessary technical infrastructure gives rise to many problems concerning preservation of cultural heritage of the Polish countryside. The selected issues are analysed on the basis of factors and determinants occurring in the area of Lubasz village in Wielkopolskie province.The pursuit of sustainable development of rural areas is fundamental in regard to ruralist solutions as well as preservation of traditional rural architecture. Ecophysiographic and cultural-historical determinants play a considerable role in this pursuit, especially in the context of threats that stem from overurbanization of rural areas.
The concentration of MMP-9 and the effects of intravenous anaesthetics on the efficacy of electroconvulsive therapy in patients with drug-resistant depression
Authors: Permoda-Pachuta Agnieszka , Skibińska Maria , Dmitrzak-Węglarz Monika , Rybakowski Filip
Published: April 2022

Introduction: This study attempts to assess the concentration of intracellular matrix metalloproteinase (MMP-9) before and after the treatment of depressive episodes with ECT therapy and also to correlate the concentration of this enzyme with the use of commonly used general anaesthetics.

Materials and methods: The study group comprised of 37 patients hospitalized in the Department of Adult Psychiatry in Poznan, with a diagnosis of episodes of drug-resistant depression during the course of bipolar and unipolar affective disorders, and who were being treated using electroconvulsive therapy. For the purpose of inducing anaesthesia during the procedure propofol was used in 10 cases, thiopental in 9 cases. Propofol was alternated with ketamine in a further 10 cases and thiopental was alternated with ketamine in another 9 cases. In order to assess the intensity of depression symptoms, the 17 point Hamilton depression scale was used, immediately before commencing ECT therapy, and one day after its completion. The serum concentration of MMP-9 was determined before and after the series of ECT treatments. In order to assess the serum concentration of MMP-9, an ELISA immunoenzymatic method was applied.

Results: In this study, a significant reduction of MMP-9 concentration was noted after therapy, relative to the starting concentration, in the serum of patients suffering from depressive episodes resulting from either unipolar or bipolar affective disorders. These results correlated with improved psychiatric state, as assessed by the Hamilton scale. A significantly lower MMP-9 concentration was noted in the serum of patients given alternating thiopental and ketamine anaesthesia.

Conclusions: This study suggests the importance of the enzyme as a biological marker for the effective treatment of depression. Furthermore, the choice of general anaesthetic applied during ECT also plays a role.
Use of a Carbon Dioxide Measurement System to Control the Process of Obtaining Breathing Air for Hyperbaric Oxygen Conditions
Authors: Woźniak Arkadiusz
Published: April 2022

Maintaining a stable carbon dioxide content in the process of producing breathing air is important both for the safety of divers performing underwater work and for avoiding financial losses resulting from poor product quality. This paper deals with the implementation of safety measurement systems for online control of the breathing air production process. On the basis of a qualified control system, the capability of the rationalised process was assessed, identifying both its current status and its potential for improvement in terms of eliminating defects caused by excessive carbon dioxide content. For process reasons, the effectiveness of online process monitoring was evaluated against the previously used periodic sample control by means of laboratory methods of instrumental analysis. The analysis was conducted at KTPP AMW1 for the compressed air supply system of the DGKN - 1202 complex.
„Cardiovascular Top Three” - Can Patients with the Most Common Cardiovascular Conditions Become Candidates for Recreational Scuba Diving?
Authors: Mańka Ewa , Skuratowicz Bartosz , Kwiatek Sebastian , Krupowies Maciej , Sieroń Karolina
Published: April 2022

Cardiovascular diseases such as coronary artery disease, hypertension, and diabetes are some of the most common conditions among the population. An ever-increasing number of recreational divers forces us to consider the impact on unprepared diving patients with cardiovascular diseases, in whom profound changes occur during the dive. People in at-risk groups should have a medical check-up before diving to minimise the risk of possible complications.
Quality and Quantity Assessment of Groundwaters in the Vicinity of Kutno with Respect to Potability. Part II
Authors: Kubiak Patryk Tomasz , Siermontowski Piotr
Published: April 2022

The study presents the characteristics of drinking water sources and subsequently performs an analysis of the deviations from the norm in terms of ions of iron, manganese, ammonia, sodium, chlorides as well as other factors affecting the quality of drinking water in the years 2015 - 2017 occurring in individual water intake points in the Kutno district.
Non-Medical risk assessment of COVID-19 in parts of Central and East Java, Indonesia
Authors: Saputra Aditya , Setiawan Wisnu , Arif Muhammad , Sriyono  , Nurmalasari Intan Rohmah , Dijaya Rohman , Ulinuha Agus , Hermawan Sigit
Published: April 2022

The impact of the Coronavirus disease 2019 (COVID-19) pandemic varies as each country has a different capacity to stop the virus transmission and apply social distancing. A densely populated country, such as Indonesia, tends to face challenges in implementing social distancing due to population characteristics. The Indonesian government focuses on the medical aspect as this virus is new and has been deadly with a high transmission rate. Meanwhile, the non-medical risk during the pandemic is still unclear. The main objective of this study is to assess the non-medical risk at the village level in two agglomeration cities of Central Java: Greater Surakarta and Surabaya. The methodologies use a risk index, derived from the risk reduction concept. The hazard refers to the death toll, while the vulnerability relates to parameters such as disaster, social and public facilities, health facilities, economics and demography. Further, the parameters were weighted based on expert judgement derived using analytical hierarchy process (AHP). The study found that the disaster aspect had the highest weight (0.38), followed by health facilities (0.31), economics (0.17), social-public facilities (0.11) and demography (0.04). The standard deviations of those parameters were relatively low, between 0.12 and 0.25. A low vulnerability index (0.05–0.36) was observed to be dominant in both study areas. There are 11 villages in Greater Surakarta and 30 villages in Greater Surabaya with high vulnerability index. Disaster-prone areas, low economic growth, lack of health facilities and aged demographic structure significantly added to this vulnerability. Further, a high-risk index (0.67–1.00) is observed in three villages in Greater Surabaya and one village in Greater Surakarta. These villages are relatively close to the city centre and have good accessibility. Furthermore, these four villages experienced the severest impact of the pandemic because the furniture and tourism sectors were their primary industries.
Back to the Future: The Rise of Human Enhancement and Potential Applications for Space Missions
Authors: Cahill Ben , Braddock Martin
Published: April 2022

Rapid advances in biology, electronics, computer and data science have turned invention into products, changing the lives and lifestyles of millions of people around the world. This mini-review will describe some remarkable progress made over the last 10 years which serves both healthy individuals and patients alike. With a forward looking lens towards long term space missions and the potential colonisation of the Moon and Mars, we discuss three technologies under development. We conclude with a distant looking perspective on the prospect of gene mediated human enhancement and highlight the importance of aligning benefit for people on Earth with goals for future space missions and the need to establish regulatory and ethical guidelines.
On Liberty and Cruelty: A Reply to Walter Block
Authors: Huemer Michael
Published: April 2022

A standard argument for ethical vegetarianism contends that factory farming – the source of nearly all animal products – is morally wrong due to its extreme cruelty, and that it is wrong to buy products produced in an extremely immoral manner. This article defends this argument against objections based on appeal to libertarian political philosophy, the supposed benefit to animals of being raised for food, and nonhuman animals’ supposed lack of rights.
Plasma Exchange in the Treatment of Relapsing Multiple Sclerosis: Case Report
Authors: Vranes Marija , Antonijevic Aleksandar , Djurovic Zivanka , Savic Maja
Published: April 2022

Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system characterized by multiple disseminated lesions. The pathogenesis of this disease is still insufficiently clarified, and the course of the disease is unpredictable. It happens that severe relapses do not respond to drug therapy and in such cases it is recommended therapeutic plasma exchange (TPE).

We present a young man with severe motor relapse, weakness of the left leg, pronounced tremor of the right arm, unstable gait and bilaterally reduction of vision. Brain magnetic resonance imaging showed a large number of chronic demyelinating lesions of the white mass, numerous were merged, with signs of brain reduction. The patient underwent five cycles of TPE, which were conducted every other day. Although TPE led to a disturbance of the hemostasis status and some biochemical parameters, the patient’s response to the applied therapy was good. The improvement of the patient’s condition was reflected through the return of vision and a moderate reduction in neurological deficit.

Despite the fact that therapeutic plasma exchange can cause some complications, it should be considered when drug therapy does not lead to improvement in these patients.
Pobreza rural y canasta básica alimentaria en la comunidad General Cárdenas, municipio de Cintalapa, Chiapas
Authors: Vesarez-Zúñiga Víctor Francisco
Published: April 2022

Objetivo: llevar a cabo un estudio socioeconómico de carácter exploratorio para identificar el nivel de pobreza de la comunidad General Cárdenas, municipio de Cintalapa, Chiapas, a partir de caracterizar su soberanía alimentaria, canasta básica y consumo de alimentos desde la perspectiva de la Teoría de la plusvalía. Metodología: levantamiento de encuesta socioeconómica realizada en el segundo semestre del año 2016 y primer trimestre del año 2017, aplicado a 87 familias de la localidad. La información obtenida se procesó con el software IBM SPSS Statistics V21 y Excel, complementada con técnicas cualitativas como la observación participante y el diario de campo. Resultados: el 95.40% de la población, percibía ingresos diarios per cápita, por debajo del nivel de pobreza internacional (1.25 USD_PPA) y el 60.92 % igual o por debajo de 1 USD_PPA, lo que los ubica, según la ONU, en condiciones de pobreza extrema, además de presentar un Coeficiente de Engel de 0.77. La ingesta diaria per cápita de la comunidad se ubicó en 2,263.66 Kcal/día, 47.76 Kcal/día (2.15%), por encima de las 2,215.90 Kcal/día per cápita normado por la CBANR y presento una disminución en su costo del orden del 4.27%. El 72.46% de las kilocalorías de la dieta lo aportaron los cereales y el frijol y existen serias carencias de alimentos formadores de origen animal. Limitaciones: se requieren nuevos marcos teóricos metodológicos, a partir de los propios actores y de su interacción con las nuevas realidades de la comunidad, para comprender su problemática y de forma participativa generar soluciones integrales. Conclusiones: existe autosuficiencia de maíz y frijol y un bajo consumo de alimentos de origen animal, factor que puede contribuir a un estado de salud vulnerable. Aunado a una limitada participación gubernamental.
Pengembangan Media Layanan Informasi Berbabis Website Untuk Stres Akademik Siswa
Authors: Arlena Nindi , Akhmad Fajar Prasetya
Published: April 2022

Penelitian ini bertujuan untuk  mengetahui kelayakan media layanan informasi berbasis website untuk stres akademik pada siswa. Jenis penelitian ini R&D (Research and Development) dengan metode Brog and Gall. Model pengembangan ini hanya sampai tahap revisi produk saja. Studi pendahuluan dengan menyebarkan instrumen angket pada siswa, serta didukung oleh hasil wawancara dengan guru BK. Subjek penelitian sebanyak 34 siswa kelas X Tatabusana 2 SMK N 2 Sewon Bantul yang menunjukan bahwa masih banyak siswa yang belu mengetahui terkait stres akademik. Hasil penelitian pengembangan ini diukur berdasarkan penillaian dari uji ahli materi dan uji ahli media. Hasil penilaian uji ahli materi mendapatkan nilai sebesar 82,5 dengan kategori Sangat Baik. Sedangkan Uji Ahli Media mendapatkan nilai sebesar 75 dengan kategori Baik. Hasil penilaian secara keseluruhan dengan nilai rata-rata yang didapat sebesar 78,8 dengan kategori Sangat Baik. Berdasarkan hasil tersebut maka Pengembangan Media Layanan Informasi Berbasis Website Untuk Stres Akademik Siswa di SMK N 2 Sewon Bantul Yogyakarta Layak untuk digunakan.

Kata kunci: Layanan Informasi, Stres Akademik, website
MENINGKATKAN MINAT MEMBACA SISWA MELALUI LAYANAN BIMBINGAN KELOMPOK DENGAN METODE SQ3R (Survey,Question,Read,Recite,Review)
Authors: Puji Dwi Pujirahayu , Ali Rachman  , Sulistiyana
Published: April 2022

Tujuan penelitian ini, yaitu untuk meningkatkan minat membaca siswa melalui layanan bimbingan kelompok dengan metode SQ3R (Survey, Question, Read, Recite, Review) pada siswa kelas XI IPS di SMAN 1 Martapura.Penelitian ini menggunakan jenis penelitian bimbingan dan konseling (PTBK) dengan menggunakan  metode penelitian kualitatif dan  dilaksanakan dalam II siklus. Sampel penelitian ini adalah siswa kelas XI IPS yang berjumlah 6 orang siswa. Adapun  teknik penarikan sampel yang digunakan adalah purposive sampling. Instrumen data yang digunakan adalah lembar observasi disertai rubrik penilaian, dilihat dari indikator keberhasilan aktivitas peneliti, aktivitas siswa dan peningkatan minat membaca siswa. Hasilenelitian ini menunjukan adanya peningkatan pada setiap siklus, untuk aktivitas peneliti mencapai kriteria “baik” untuk aktivitas siswa mencapai kriteria “aktif” dan untuk peningkatan minat membaca siswa melalui layanan bimbingan kelompok menggunakan metode SQ3R mencapai kriteria “meningkat”. Kesimpulan dari penelitian ini adalah layanan bimbingan kelompok dengan metode SQ3R (Survey, Question, Read, Recite, Review) dapateningkatkan minat membaca siswa
Effects Of Good Corporate Governance And Corporaate Social Responsibility Towards Firm Value
Authors: Yusbardini  , Edward Widjaja
Published: April 2022

This research’s purpose is to see if VF is effected by GCG and CSR, this research is made due to the results that the author has read from the previous research, where in some cases resulted GCGhas an effect towards VF and in some other case only CSR has an effect towardsVF. Thus the author decided to create this research in hope to clear the fluctuation of the previous research, the author hopes that this research can help investors that want to invest their funds and also the people reading this article The sample of the research is picked using the purposive sampling method thus leaving 4 Government banks. Based on the Multiple linier regression it can be concluded that GCG has a positive impact on Value of the Firm and CSR also has a positive impact on VF.
Enhancing Repurchase Intention at Warung Kopi Tepi Sungai Depok: The Role of Customer Experience
Authors: Simanihuruk Maidar , Kusumawardhani Yuviani , Audilla Lovita Susan
Published: April 2022

The most important stage in winning customers' hearts is through experience, building a customer experience is an essential part of any marketing strategy. The higher the impact on customer pleasure and the willingness to return and acquire the products sold, the better the customer experience. Warung Kopi Tepi Sungai Depok has various advantages despite its less-than-ideal location. It provides guests with comfort and a peaceful rural setting. The purpose of this research is to see how customer experience affects repurchase intent at Warung Kopi Tepi Sungai Depok. Quantitative methods were employed in the research to gather more comprehensive, valid, reliable, and objective data. A total of 101 customers who visited the café were included in the sample. Both factor and regression analysis was employed in the data analysis. Customer experience had a substantial impact on repurchase intention (t = 8.356 > t table with a significance of 0.000 (? < 0.05). With its interior design and unique style, the customer experience at Warung Kopi Tepi Sungai Depok has a dominant influence on influencing repurchase intention, and consumers are interested in returning to this place. The author makes a suggestion, advising that more attention be paid to and development of the website be done in order to establish direct contacts with clients. This cafe has to improve its services, offer new menu items, and keep its facilities clean. Then Warung Kopi Tepi Sungai Depok will be the top option of the customers.

Keywords: Repurchase Intention, Customer Experience, Revisit Intention
Cytotoxic effects of CeO2 NPs and β-Carotene and their ability to induce apoptosis in human breast normal and cancer cell lines
Authors: Al-Ali Ali A.A. , Alsalami Khalid A. S. , Athbi Ahmed Muhssin
Published: April 2022

Cerium Oxide Nanoparticles (CeO2 NPs) and β-carotene are natural-source products that have recently gained an increased interest as pharmaceutical additives because of their effectiveness in living systems, but the behavior of these substances varies according to factors and conditions. The above mentioned materials were evaluated in breast normal (HBL-100) and cancer cell lines (CAL-51 and MCF-7 ) by  different techniques ; MTT assay for studying cytotoxic effects, morphological changes, sqPCR, including gene expression of caspases 8 and 9, and P53. All experiments were conducted on cell lines by the use of the materials alone as well as their combination.                                                                                                                                             
    The results of the MTT assay showed that the two materials (CeO2 NPs and β-carotene) had a toxic effect on the cell lines, and the toxicity of the materials was concentration-dependent. The half maximal inhibitory concentration (IC50) values of CeO2 NPs and β-Carotene, as observed by the effects in all cell lines, have significant differences. 
   Our findings showed that CeO2 NPs has a higher toxicity on the HBL-100 and MCF-7 cell lines compared with β-Carotene. The toxic effects of each material alone and combined  together  were reflected on cell morphology by the appearance of irreversible cytopathic changes in the treated cells. The two materials had the ability to cause cellular death and DNA damage, inducing the external pathway of apoptosis. A significant increase in the gene expression of caspase 8 appeared at P≤0.05.  Collectively, the CeO2 NPs and β-Carotene have an inhibitory effect on both breast cancer and normal cell lines. We conclude the both materials have genotoxic effects on normal and cancer cell lines.
Mean Latin Hypercube Runge-Kutta Method to Solve the Influenza Model
Authors: Mohammed Shatha Jabbar , Mohammed Maha A.
Published: April 2022

In this study, we propose a suitable solution for a non-linear system of ordinary differential equations (ODE) of the first order with the initial value problems (IVP) that contains multi variables and multi-parameters with missing real data. To solve the mentioned system, a new modified numerical simulation method is created for the first time which is called Mean Latin Hypercube Runge-Kutta (MLHRK). This method can be obtained by combining the Runge-Kutta (RK) method with the statistical simulation procedure which is the Latin Hypercube Sampling (LHS) method. The present work is applied to the influenza epidemic model in Australia in 1919  for a previous study. The comparison between the numerical and numerical simulation results is done, discussed and tabulated. The behavior of subpopulations is shown graphically. MLHRK method can reduce the number of numerical iterations of RK, and the number of LHS simulations, thus it saves time, effort, and cost.  As well as it is a faster simulation over the distribution of the LHS. The MLHRK method has been proven to be effective, reliable, and  convergent to solve a wide range of linear and nonlinear problems. The proposed method can predict the future behavior of the population under study in analyzing the behavior of some epidemiological models.
Synthesis, Characterizations, and Magnetic Properties of Mixed Spinel Mg1-xZnxFe2O4 Ferrites
Authors: Sami We'am , Sadeq Zainab Sabeeh
Published: April 2022

Mixed spinel Mg1-xZnxFe2O4 ferrites (where x = 0, 0.2, 0.4, and 0.6) nanoparticles were synthesized by using microwave-assisted combustion route. As-synthesized powdered samples were checked by XRD analysis, field emission-scanning electron microscopy, and vibration sample magnetometer to investigate the structural,   morphology, and magnetic properties, respectively. XRD results exhibited that the crystallite size increases with the decrease of Zn+2 ion concentration for series of mixed spinel Mg1-xZnxFe2O4 ferrite expect x=0.2. All the mixed spinel Mg1-xZnxFe2O4 ferrite has different grain sizes with uniform distribution also presence voids in the samples. Pure magnesium ferrite has a lower net magnetization value but when magnesium ions (Mg+2) are replaced by zinc ions (Zn+2) then the value of saturation magnetization increases.
Effect of silver nitrate and putrescine on in vitro shoot organogenesis of Polygonum multiflorum
Authors: Park Woo Tae , Kim Yeon Bok , Sathasivam Ramaraj , Kim Haeng-Hoon , Park Sang Un
Published: April 2022

Polygonum multiflorum is a flowering plant that belongs to the family Polygonaceae and it is commonly used for medicinal and ornamental purposes. Few studies have been studied about the regeneration of this species. Therefore, we aimed to develop a suitable protocol for regeneration and subsequent growth of shoots by comparing the silver nitrate (AgNO3) (ethylene inhibitor) and the putrescine (polyamine). Internode explants were cultured on shoot regeneration media (Murashige and Skoog (MS) media containing 2 mg L-1 of 6-benzylaminopurine). To analysis, the effect of AgNO3 and putrescine on shoot regeneration and length, different concentrations (mg L-1) of AgNO3 (0, 1, 5, 7, 10, and 20) and putrescine (0, 10, 30, 50, 100, and 200) were added to the MS media. The result showed that at highest concentration (20 mg L-1) of AgNO3 treatment decrease number of shoots (NOS) (1.4 ± 0.2 mm) and shoot length (9.7 ± 1.6 mm) was observed. Putrescine considerably increased the regeneration efficiency, NOS per explant, and shoot length in all the concentrations when compared to AgNO3 treatment. Among the different concentrations, the highest NOS (2.52 ± 0.2 mm) was obtained in cultures supplemented with 30 mg L-1 putrescine, whereas the further increase in putrescine concentration reduced shoot regeneration. The longest shoots (20.5 ± 1.7 mm) were achieved in cultures supplemented with 200 mg L-1 putrescine. The findings of this study indicate that the addition of putrescine to the media could be suitable for P. multiflorum micropropagation and plant transformation.
UPAYA MENGURANGI DAMPAK KELUHAN MASYARAKAT DALAM MELAKSANAKAN WORK FROM HOME SAAT PANDEMI COVID 19
Authors: Septiani Winnie , Astuti Pudji , Faradilla Arnes , Purwanto Iwan
Published: April 2022

WFH merupakan salah satu upaya untuk mengurangi risiko penyebaran virus Covid 19. Kebijakan tersebut berdampak terhadap aktivitas berbagai sektor pemerintahan, industri dan pendidikan. Pelatihan ini diberikan dengan tujuan untuk memberikan penyuluhan kepada masyarakat agar tetap sehat dan produktif selama WFH. Pelatihan ini dimulai dengan menyebarkan kuesioner melalui melalui google form yang diisi oleh 135 responden masyarakat indonesia yang melaksanakan WFH. Selain itu dilakukan survey secara langsung di lingkungan masyarakat kota Bekasi. Hasil identifikasi keluhan tersebut menjadi dasar dalam menyusun materi pelatihan sebagai upaya untuk mengurangi keluhan masyarakat dalam melaksanakan WFH saat pandemi Covid 19. Keluhan fisik yang teridentifikasi seperti sakit di bagian punggung, bahu, kepala, mata dan keluhan mental seperti cemas, tidak fokus, emosi tidak terkontrol dan lain sebagainya. Pelatihan dilaksanakan secara daring dengan menggunakan Zoom dan live streaming youtube, facebook dan instagram. Materi yang diberikan mengenai fasilitas dan lingkungan kerja yang ergonomis serta penggunaan aplikasi teknologi untuk menunjang WFH. Hasil evaluasi pelatihan menunjukan 73.4% peserta menyatakan pelatihan ini menarik dan bermanfaat.
PENGARUH COST OF PRODUCTION TERHADAP VOLUME PENJUALAN PADA PERUSAHAAN TUNGKU CAFE AND RESTO BANJAR
Authors: Indriani Lena , Sukomo Sukomo , Mulyadi Endang
Published: April 2022

Pelaku bisnis di era globalisasi dituntut untuk bekerja lebih efektif, efisien dan produktif dalam menciptakan sebuah produk. Biaya yang digunakan oleh perusahaan dalam menjalankan proses produksi yaitu biaya produksi. Besar kecilnya biaya produksi yang dikeluarkan akan berpengaruh terhadap volume penjualan suatu perusahaan. Tujuan penelitian ini adalah untuk mengetahui (1) Besarnya perkembangan cost of production pada Tungku Cafe and Resto; (2) Besarnya perkembangan volume penjualan pada Tungku Cafe and Resto;(3) Besarnya pengaruh cost of production  terhadap volume penjualan pada Tungku Cafe and Resto. Metode penelitian yang digunakan dalam penelitian adalah metode deskriptif dengan menggunakan teknik pengumpulan data secara langsung melalui observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa (1) Besarnya perkembangan cost of production yang dikeluarkan oleh Tungku Cafe and Resto Banjar selama periode 2016 sampai 2020 berfluktuatif cenderung naik, dengan rata-rata setiap tahunnya mengalami kenaikan sebesar 8,62%;(2) Besarnya tingkat volume penjualan yang dihasilkan oleh Tungku Cafe and Resto Banjar selama periode 2016 sampai 2020 berfluktuatif dengan rata-rata setiap tahunnya mengalami kenaikan sebesar 8,89%;(3) Terdapat pengaruh yang positif dan signifikan cost of production terhadap volume penjualan pada Tungku Cafe and Resto Banjar selama periode 2016 sampai 2020, adapun besarnya pengaruh sebesar 87,05%.Kata Kunci : Cost Of Production, Volume Penjualan.
MENINGKATKAN HASIL BELAJAR SISWA MELALUI MODEL PEMBELAJARAN KOOPERATIF TIPE MAKE A MATCH DENGAN MENGGUNAKAN METODE TANYA JAWAB DI KELAS X SMAN 1 CISAGA
Authors: Hasieba Iqra Yaomalieka , Rohaeni Eni , Ruhyanto Ahyo
Published: April 2022

ABSTRAKIqra Yaomalieka Hasieba (2021) “Pengaruh Model Pembelajaran Kooperatif tipe Make a Match dengan menggunakan Metode Tanya Jawab Terhadap Hasil Belajar Siswa pada mata pelajaran Ekonomi Di Kelas X SMAN 1 CISAGA (Studi Eksperimen di Kelas X pada Kompetensi Dasar 3.7 Mendeskripsikan Konsep Manajemen di SMAN 1 CISAGA)” . Penulisan skripsi ini dibawah bimbingan Ibu Hj. Eni Rohaeni, Dra., M.M sebagai Pembimbing I dan Bapak H. Ahyo Ruhyanto, Drs., M.Pd sebagai Pembimbing II.Hasil belajar merupakan kemampuan yang diperoleh siswa setelah melalui proses belajar. Hasil belajar juga menjadi tolak ukur keberhasilan suatu pembelajaran. Rendahnya hasil belajar siswa disebabkan oleh beberapa faktor, diantaranya adalah kurang tepat nya penerapan model pembelajaran dengan materi yang diajarkan. Salah satu model pembelajaran yang dapat digunakan yaitu model pembelajaran kooperatif tipe Make a Match. Rumusan masalah dalam penelitian ini yaitu : 1) Apakah terdapat perbedaan hasil belajar siswa yang menggunakan model pembelajaran kooperatif tipe Make a Match dan metode tanya jawab pada pengukuran awal (pretest) dan pengukuran akhir (posttest) di kelas Eksperimen? 2) Apakah terdapat perbedaan hasil belajar siswa yang menggunakan metode konvensional pada pengukuran awal (pretest) dan pengukuran akhir (posttest) di kelas Kontrol? 3) Apakah terdapat perbedaan hasil belajar siswa yang menggunakan model pembelajaran kooperatif tipe Make a Match dan metode tanya jawab dengan hasil belajar siswa yang menggunakan metode konvensional pada pengukuran akhir (posttest)? Tujuan dari penelitian ini yaitu untuk mengetahui : 1) Perbedaan hasil belajar siswa yang menggunakan model pembelajaran kooperatif tipe Make a Match dan metode tanya jawab pada pengukuran awal (pretest) dan pengukuran akhir (posttest) di kelas Eksperimen. 2) Perbedaan hasil belajar siswa yang menggunakan metode konvensional pada pengukuran awal (pretest) dan pengukuran akhir (posttest) di kelas Kontrol. 3) Perbedaan hasil belajar siswa yang menggunakan model pembelajaran kooperatif tipe Make a Match dan metode tanya jawab dengan hasil belajar siswa yang menggunakan metode konvensional pada pengukuran akhir (posttest). Metode penelitian yang digunakan yaitu metode eksperimen tipe Quasi Eksperimen. Hasil penelitian ini menunjukan bahwa model pembelajaran Make a Match berpengaruh signifikan terhadap hasil belajar siswa.  Kata kunci : Model pembelajaran Make a Match, hasil belajar
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE CONTEXTUAL TEACHING AND LEARNING (CTL) TERHADAP HASIL BELAJAR SISWA
Authors: Maretiana Desta Nur , Mulyadi Ilah , Ruhyanto Ahyo
Published: April 2022

Pengaruh Model Pembelajaran Kooperatif tipe Contextual Teaching and Learning (CTL) Terhadap Hasil Belajar Siswa
MENINGKATKAN HASIL BELAJAR MELALUI MODEL PEMBELAJARAN KOOPERATIF TIPE STUDENT FACILITATOR AND EXPLAINING
Authors: Noer Arofah Ucu Siti , Samiri Samiri , Heryati Tati
Published: April 2022

Rendahnya hasil belajar peserta didik merupakan masalah dalam penelitian ini, karena hasil belajar merupakan salah satu tolok ukur keberhasilan proses pembelajaran, maka pendidik dituntut untuk segera mencari berbagai upaya untuk mencapai keberhasilan, rendahnya hasil belajar dilatarbelakangi oleh berbagai faktor diantaranya pemilihan model pembelajaran dengan tipe yang tidak tepat digunakan oleh pendidik, adapun tujuan dari penelitian ini: (1) Perbedaan hasil belajar peserta didik di kelas eksperimen yang menggunakan model pembelajaran kooperatif tipe student facilitator and explaining. (2) Perbedaan hasil belajar peserta didik di kelas kontrol yang menggunakan metode pembelajaran konvensional. (3) Perbedaan hasil belajar peserta didik yang menggunakan Model Pembelajaran Kooperatif tipe Student Facilitator and explaining dengan yang menggunakan Metode Pembelajaran Konvensional.Metode penelitian yang digunakan adalah Quasi Eksperimental Design. Teknik pengumpulan data dilakukan dengan melalui test, metode observasi dan metode dokumentasi. Kesimpulan dari penelitian bahwa hasil belajar peserta didik yang menggunakan Model Pembelajaran Kooperatif tipe Student Facilitator and explaining lebih efektif dibanding hasil belajar peserta didik yang menggunakan metode pembelajaran konvensional. Artinya bahwa Model Pembelajaran Kooperatif tipe Student Facilitator and explaining Aktif dapat meningkatkan hasil belajar peserta didik.Kata Kunci: Model Pembelajaran Kooperatif tipe Student Facilitator and explaining, Hasil Belajar
EFEKTIVITAS EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L) TERHADAP PERTUMBUHAN RAMBUT PADA HEWAN UJI KELINCI LOKAL (Lepus nigricollis)
Authors: Priatna Aas Aisyiah , Erlin Euis , Romansyah Romdah
Published: April 2022

Adanya efek samping dari penggunaan bahan kimia terhadap rambut maka penggunaan bahan tradisional menjadi alternatif terhadap pertumbuhan rambut. Penggunaan bahan tradisional yang mudah didapat dan mudah dijumpai yaitu belimbing wuluh (Averrhoa bilimbi L). Daun belimbing wuluh mengandung senyawa aktif yaitu flavonoid, saponin, tanin, asam format, sulfur, kalsium oksalat dan kalium nitrat. Senyawa seperti flavonoid, saponin, tanin dan alkaloid merupakan senyawa yang berperan aktif untuk pertumbuhan rambut. Tujuan penelitian ini adalah untuk mengetahui keefektifan ekstrak daun belimbing wuluh terhadap pertumbuhan rambut pada hewan uji kelinci lokal dan konsentrasi paling efektif. Penelitian dilaksanakan dari bulan Maret sampai dengan bulan Juli 2021. Desain penelitian yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan 6 perlakuan diantaranya yaitu (P0) tanpa pemberian ekstrak, (P1) konsentrasi ekstrak 2,5%, (P2) konsentrasi ekstrak 5%, (P3) konsentrasi ekstrak 7,5%, (P4) konsentrasi ekstrak 10% dan (P5) konsentrasi ekstrak 12,5%. Parameter yang diamati yaitu rata-rata panjang rambut kelinci. Data hasil pengukuran pertumbuhan panjang rambut diuji statistik dengan teknik ANAVA satu faktor. Hasil dari penelitian menunjukkan bahwa ekstrak daun belimbing wuluh (Averrhoa bilimbi L) efektif terhadap pertumbuhan rambut pada hewan uji kelinci lokal (Lepus nigricollis) dengan konsentrasi yang paling efektif yaitu konsentrasi ekstrak 10%.
STUDI DOKUMENTER MODEL PEMBELAJARAN CONTEXTUAL TEACHING AND LEARNING (CTL) TERHADAP HASIL BELAJAR SISWA PADA MATERI BIOTEKNOLOGI DI MAN 1 PANGANDARAN
Authors: Lelasari Siska Nur , Yati Nur Ilmi , Setia Budi Setia
Published: April 2022

Model Pembelajaran CTL dari pendapat para tokoh-tokoh dapat kita simpulkan bahwa CTL adalah konsep belajar yang membantu guru mengkaitkan antara materi yang diajarkanya dengan situasi dunia nyata siswa dan mendorong siswa membuat hubungan antara pengetahuan yang dimilikinya dengan penerapan dalam kehidupan sehari-hari. Ditinjau dari segi bahasa, hasil belajar diartikan sebagai hasil yang dicapai seseorang yang ditunjukkan oleh apa yang telah digunakan sebagai alat ukur untuk melihat tingkat keberhasilan setelah melakukan usaha tertentu. Bioteknologi merupakan salah satu pembelajaran biologi dalam penggunaan makhluk hidup dan proses didalamnya untuk menghasilkan produk tertentu. Bioteknologi memanfaatkan bakteri, ragi, alga, sel tumbuhan, atau jaringan hewan. Penerapan bioteknologi memadukan berbagai disiplin ilmu, seperti mikrobiologi, biokimia, genetika, biologi molekuler, kimia, rekayasa proses, dan teknik kimia. Tujuan Penelitian adalah untuk mengetahui pengaruh model pembelajaran CTL terhadap hasil belajar siswa pada materi bioteknologi di MAN 1 Pangandaran. Penelitian dilaksanakan pada bulan April 2021. Subjek penelitian ini adalah dokumen hasil belajar siswa kelas XII IPA 1 sebanyak 25 orang. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif. Instrumen yang digunakan dokumen hasil belajar siswa model CTL, pedoman wawancara, observasi, serta beberapa dokumen lain yang dapat mempengaruhi hasil belajar diantaranya RPP, bahan ajar yang digunakan, serta media pembelajaran. Teknis analisis data melalui reduksi, menyajikan data, dan analisis data. Hasil penelitian menunjukan bahwa hasil belajar siswa menggunakan model CTL berada dalam kategori baik. Ketercapaian tersebut tentunya tidak terlepas dari berbagai faktor baik dalam diri siswa maupun dari lingkungan belajar.
NILAI-NILAI FILOSOFIS TRADISI AMONG-AMONG DESA PURWADADI KABUPATEN CIAMIS
Authors: Hartanto Ajeng Febya Anindita , Wijayanti Yeni , Nurholis Egi
Published: April 2022

Tradisi among-among adalah alkulturasi tradisi Jawa yang telah berkembang dan dilaksanakan secara turun-temurun oleh masyarakat Purwadadi. Tradisi among-among adalah salah satu syukuran sederhana kepada Allah SWT. Metode penelitian yang digunakan yakni metode sejarah (historis). Adapun langkah-langkah penelitian sejarah tersebut meliputi: heuristik, kritik, interpretasi dan historiografi. Teknik pengumpulan data yang digunakan dalam penelitian ini yaitu: studi literatur, wawancara, observasi, dan dokumentasi. Hasil penelitian ini menunjukan bahwa tradisi among-among merupakan tradisi Jawa yang berakulturasi ke Desa Purwadadi, karena letaknya berbatasan dengan daerah Jawa Tengah. Tujuan adanya among-among yakni bentuk syukur kepada Allah SWT atas nikmat yang di berikan. Biasanya among-among dilaksanakan pada siang atau sore hari. Makanan dan peralatan yang mengandung makna simbolik among-among yakni: nasi putih, bubur merah dan putih, urab (sayuran yang direbus), telur rebus, tampah, air dalam wadah yang diberi daun dadap, dan jajanan pasar. Nilai filosofis didalam tradisi among-among yakni nilai religi, nilai sosial, dan nilai pendidikan.
UPAYA PENINGKATAN KOMPETENSI GURU MENYUSUN PERANGKAT PEMBELAJARAN MELALUI SIPERVISI AKADEMIK DI SD NEGERI KEPENDILAN
Authors: Komariyah Komariyah
Published: April 2022

Keberhasilan sebuah program apabila pelaksanaannya dilakukan secara sungguh-sungguh, berkesinambungan, dilakukan pengawasan, pendampingan serta evaluasi. Dari titik inilah diperlukan layanan supervisi dalam kelangsungan pendidikan terutama dalam proses pembelajaran. Penelitian ini bertujuan untuk meningkatkan kompetensi guru dalam menyusun perangkat pembelajaran melalui supervisi akademik. Metode yang digunakan adalah Penelitian Tindakan Sekolah (PTS). Teknik pengumpulan data yang digunakan adalah non tes diantaranya observasi/ pengamatan dan studi dokumen. Instrumen yang digunakan adalah lembar observasi berupa rubrik, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa skor pada guru kelas IV mengalami kenaikan dari 75 pada siklus I menjadi 83,5 pada siklus II dengan kategori baik. Begitupun pada guru kelas V mengalami kenaikan dari 73,25 pada siklus I menjadi 83,5 pada siklus II dengan kategori baik. Maka dapat disimpulkan bahwa supervisi akademik telah berhasil untuk meningkatkan kompetensi guru dalam menyusun perangkat pembelajaran.