bluuebunny/crossref_metadata_2025 huggingface dataset:
Kültürel Kimliğin Sürdürülebilmesinde Bir Araç Olarak Grafik Elemanlar
Authors: Sancar Özyavuz Kıymet , Aktepe Özbayrak Kübra , Midilli Sarı Reyhan
Published: June 2023

Bir kentin sahip olduğu kültürel kimliği, geçmişten günümüze ulaşan süreç sonucunda oluşmuştur. Kültürel kimlik kavramı; o kentin tarihi, mimarisi, müziği, geleneği, göreneği gibi bilimden sanata birçok alanı kapsamaktadır. Birçok etkenle birlikte sürekli değişim halinde olan günümüz koşullarında bu somut ve soyut kültürel değerlerin gelecek nesillere aktarılarak varlığını koruyabilmesi için, sürdürülebilirliğinin sağlanması gerekmektedir.
Çalışmada, kültürel kimliğin sürdürülebilirliğin sağlanabilmesi amacıyla kültürü oluşturan etmenlerin soyutlanarak grafik elemanlara dönüştürülmesi amaçlanmıştır. Çalışma alanı olarak zengin kültürel birikime sahip olan ve son yıllarda yapılan müdahalelerle bu kültürel izleri kaybetmeye başlayan Trabzon kenti seçilmiştir. Trabzon kentini en iyi tanımlayan/kimliğini oluşturan kültürel unsurlar yapılan bir anket sonucu belirlenmiştir. Belirlenen unsurlar için anlamsal ve biçimsel soyutlama uygulamalarının yapıldığı çalışmada, kentlerin özgün değerlerini koruyabilmesi ve kültürel izlerini sürdürebilmesi için kentsel mekânlarda kullanımı kaçınılmaz olan grafik yüzeylerin tasarımı için soyutlama önerileri sunulmuştur.
Electroacupuncture Inhibits Ferroptosis Induced by Cerebral Ischemiareperfusion
Authors: Wang Gui-Ling , Xu Shu-Ying , Lv He-Qun , Zhang Chao , Peng Yong-Jun
Published: June 2023

Background:

Electroacupuncture (EA) treatment has been recommended by World
Health Organization (WHO) for years on cerebral ischemia treatment, but the specific mechanism
is still elusive. Studies have shown that EA can relieve brain damage after ischemic stroke by inhibiting
programmed cell death (PCD), such as apoptosis, necroptosis, and autophagy. Ferroptosis,
a unique form of cell death, has been highlighted recently and found to occur in I/R injury. We,
therefore, investigated whether EA plays an essential role in relieving cerebral I/R injury via ferroptosis.

Methods:

The modified MCAO/R rats model was established and then divided into four groups
with or without EA treatment. Neurological deficit score and TTC staining were used to evaluate
the neurological deficit and infarct volume of each group. Transmission electron microscope
(TEM) and immunofluorescence staining were applied for mitochondrial ultrastructure and ROS
accumulation observation, respectively. The proteins and mRNA expression of ACSL4, TFR1, and
GPX4 were assessed by western blot and qPCR to detect the progress of ferroptosis.

Results:

EA treatment improved neurological deficits and reduced infarct volume. Moreover, EA
significantly relieved the mitochondrial morphological changes and inhibited ROS Production in
MCAO rats. In terms of its mechanism, EA obviously decreased the ACSL4 and TFR1 expressions
and promoted GPX4 levels in MCAO/R model rats.

Conclusion:

These findings indicate that EA might play an essential role in relieving cerebral I/R
injury via ferroptosis.
Does Patisiran Reduce Ocular Transthyretin Synthesis? A Pilot Study of
Two Cases
Authors: Cambieri Chiara , Marenco Marco , Colasanti Tania , Mancone Carmine , Corsi Alessandro , Riminucci Mara , Libonati Laura , Moret Federica , Chimenti Cristina , Lambiase Alessandro , Conti Fabrizio , Garibaldi Matteo , Inghilleri Maurizio , Ceccanti Marco
Published: June 2023

Background:

Variant transthyretin-mediated amyloidosis (ATTR-v) is a well-characterized
disease affecting the neurologic and cardiovascular systems. Patisiran has been approved for neurologic
involvement as it reduces hepatic synthesis of transthyretin (TTR). Eye involvement is a lateonset
feature increasing the risk of glaucoma and cataracts in patients.

Aims:

The aim of this case series was to assess whether patisiran can effectively reduce TTR synthesis
in such a barrier-protected organ as the eye.

Methods:

Two patisiran-treated ATTR-v patients underwent serum and aqueous humor sampling to
measure TTR levels detected by SDS-PAGE and immunoblotting. Serum samples were compared to
healthy control (HC), whereas aqueous humor samples were compared to non-amyloidotic subjects affected
by cataracts and glaucoma.

Results:

Serum TTR levels representative of hepatic synthesis were sharply lower in treated patients if
compared to the HC (-87.5% and -93.75%, respectively). Aqueous humor TTR levels showed mild-tono
reduction in treated patients compared to non-amyloidotic subjects with cataracts (-34.9% and
+8.1%, respectively) and glaucoma (-41.1% and -2.1%).

Conclusions:

Patisiran does not seem to be as effective in inhibiting ocular TTR synthesis as it is in
inhibiting hepatic synthesis. Re-engineering the envelope could allow the drug to target RPE cells thus
avoiding any ocular involvement.
A relação colaborativa na formação continuada com professores de educação física da educação infantil
Authors: Freitas Marchiori Alexandre , Da Silva Mello André
Published: June 2023

No artigo, analisa-se a formação continuada com professores de Educação Física da Educação Infantil de Vitória/Brasil, desenvolvida por meio de parceria entre docentes da Universidade e da Educação Básica. A formação esteve centrada nas práticas pedagógicas dos participantes e nas reflexões sobre elas, que foram sistematizadas na produção de material didático-pedagógico com professores da educação infantil da capital capixaba. Trata-se de uma pesquisa-ação colaborativa, realizada entre 2019 e 2020, que contou com a participação de 27 docentes vinculados à Universidade Federal do Espírito Santo e à Secretaria Municipal de Educação. Os dados foram produzidos por meio da observação participante e registrada em diário de campo. A análise de conteúdo dos dados contribuiu para a formulação das seguintes categorias temáticas: a) a formação como lugar de afetos e afecções: memória de futuro; b) a pluralidade de vozes no compartilhamento das experiências e na ação colaborativa entre professores e equipe formadora; e c) a escrita no processo de formação dos professores: a produção do material didático-pedagógico. Os resultados indicaram a perspectiva dos docentes como pesquisadores da própria prática e o reconhecimento dos professores das instituições infantis como produtores de conhecimentos. O processo autoral, na produção colaborativa de um material didático-pedagógico, contribui para a formação dos participantes, aproximando-os das dimensões política e emancipatória da escrita.
PENGARUH UMUR PEMAKAIAN ZEOLIT ALAM DAN ARANG DALAM PENYARINGAN AIR SUMUR SISTEM ADSORPSI TERHADAP KUALITAS BAKTERIOLOGIS AIR
Authors: Yulianti Dwiana Muflihah , Aminatun Tien , Yulianti Yuliati
Published: June 2023

Penelitian ini bertujuan untuk mengetahui efektivitas pemakaian zeolit alam dan arang dalam pengolahan air sumur sistem adsorpsi terhadap kualitas bakteriologis air ditinjau dari indeks MPN coliform dan colifekal. Selain itu juga, untuk mengetahui lama batas umur pemakaian maksimal zeolit alam dan arang dalam pengolahan air sumur sistem adsorpsi terhadap kualitas bakteriologis air. Penelitian ini dilakukan selama 3 bulan pada bulan Juni, Juli dan Agustus 2015 dengan pengecekan setiap bulan sekali dengan 3 kali ulangan. Sampel yang digunakan adalah air sumur sebelum dilewatkan dan sesudah dilewatkan pada alat penyaringan air sumur sistem adsorpsi menggunakan zeolit alam dan arang. Selanjutnya sampel air sumur tersebut dihitung nilai MPN coliform total dan colifekalnya dan dianalisis menggunakan metode deskriptif dan dikomparasikan dengan standar baku mutu air pada PERMENKES no. 416/ MENKES/ PER/ IX/ 1990. Selain itu, dilakukan penghitungan persentase efektivitas alat dalam menyaring bakteri untuk mengetahui batas pemakaian alat penyaringan air sistem adsorpsi. Hasil penelitian ini didapatkan data, nilai MPN coliform yang telah dilewatkan pada alat penyaring air sumur yaitu 34 dan 35 MPN/100 ml, sudah memenuhi kriteria baku mutu air yang ditetapkan yaitu berada ≤ 50/100 ml kecuali nilai MPN coliform air sumur pada bulan ke-0. Persentase efektivitas tertinggi alat penyaring sebesar 87,86% untuk penyaringan bakteri coliform total dan 85,20% untuk penyaringan bakteri colifekal. Persentase efektivitas alat menunjukkan kecenderungan penurunan setelah satu bulan pemakaian, sehingga batas umur pemakaian  zeolit alam dan arang maksimal dalam alat penyaring air sumur sistem adsorpsi adalah satu bulan.Kata kunci: zeolit alam, arang, adsorpsi, bakteriologis air
HUBUNGAN KEKERABATAN ANGGREK DENDROBIUM BERDASARKAN KARAKTERISTIK MORFOLOGIS DAN ANATOMIS DAUN
Authors: Arif Ahmad , Ratnawati Ratnawati
Published: June 2023

Tujuan penelitian ini yaitu mendeskripsikan karakteristik struktur morfologis dan anatomis daun antarjenisanggrek Dendrobium serta mendeskripsikan hubungan kekerabatan antarjenis anggrek Dendrobium pada tingkatkesamaan 70%. Sampel dari ke-15 spesies yaitu D. aphyllum, D. atavus, D. discolor, D. fimbriatum, D.indragiriense, D. laxiflorum, D. moschatum, D. mutabile, D. phalaenopsis, D. sagittatum, D. sanguinolentum, D.smilliae, D. anosmum, D. secundum, dan D. faciferum yang terdapat di Rumah Anggrek Palagan Orchids diamatisecara morfologis dan anatomis. Hasil analisis pada kesamaan antarjenis sebesar 70% didapat 7 klaster. Klaster 1terdiri dari D. mutabile dan D. aphyllum; Klaster 2 terdiri dari D. anosmum; Klaster 3 teriri dari D. faciferum, D.moschatum, D. sanguinolentum, D. laxiflorum dan D. indragiriense; Klaster 4 terdiri dari D. smiliae, D.phalaenopsis, D. fimbriatum, dan D. atavus; Klaster 5 terdiri dari D. discolor; Klaster 6 terdiri dari D. saggitatum;Klaster 7 terdiri dari D. secundum.Kata kunci: Hubungan kekerabatan, daun, Anggrek, Dendrobium, karakter morfologis, karakter anatomis
Sleep problems in adults assisted in the Family Health Strategy
Authors: Aragão Núbia Samara Caribé de , Rodrigues Éder Pereira , Nery Adriana Alves , Tironi Márcia Oliveira Staffa , Nascimento Mônica de Andrade , Sobrinho Carlito Lopes Nascimento
Published: June 2023

Objective: To estimate the prevalence and investigate factors associated with sleep problems in adults enrolled in the Family Health Strategy in 2016. Methods: Cross-sectional sample study with 791 individuals aged 18 years or over, conducted between 2017 and 2018. Sleep problems were measured using the Mini Sleep Questionnaire, a questionnaire validated in Brazil. Results: The prevalence of sleep problems was 49.6%. Of these, 10.4% had mild, 7.6% moderate, and 31.6% severe alterations. There was a statistically significant association between not having a paid work activity, not having leisure activities, smoking, chronic disease, and negative self-assessment of health with sleep problems. Conclusion: There was a high prevalence of sleep problems. These results can contribute to a better understanding of sleep problems in the adult population and thus collaborate with adopting more effective measures to treat them.
Empirical antimicrobial therapy based on active surveillance cultures in ICU patients
Authors: Ramos Silva Alice , Nagem Lopes Luis Phillipe , Fernandez-Llimos Fernando , Costa Lima Elisangela
Published: June 2023

Objective: To assess the predictive value of prior carbapenem-resistant Acinetobacter baumannii (CRAB) and Pseudomonas aeruginosa (CRPA) colonization established in surveillance cultures for subsequent infection by these pathogens in ICU patients. Methods: A cohort study was performed with patients admitted to the intensive care unit for at least 48 h. Negative and positive predictive values, sensitivity, and specificity of surveillance cultures in CRAB and CRPA were measured. Results: 693 infected patients were included. Patients previously colonized by CRAB and CRPA were more likely to be infected by these pathogens: adjusted OR: 10.34 (6.58 - 16.45; p < 0.001) and 2.30 (3.88 - 10.26; p < 0.001), respectively. We found high negative predictive values of surveillance cultures for CRAB (87.18%) and CRPA (88.30%) and high specificity 91.96% and 90.13%, respectively. Conclusions: Patients not colonized by CRAB and CRPA were less prone to infection by these pathogens. These findings may contribute to the choice of empirical antimicrobial therapy and discourage the prescription of antibiotics against these pathogens in patients without previous colonization.
Impact of the COVID-19 pandemic on the performance of pediatricians and pediatric dentists in the Brazilian Unified Health System
Authors: Santana Davi Moreira , Barbosa-Lima Ricardo , Andrade Alexandre Machado de
Published: June 2023

Objective: To evaluate the impact of the COVID-19 pandemic on the outpatient production of pediatricians and pediatric dentists in the Brazilian Unified Health System (SUS). Methods: An ecological study was carried out with an analytical and quantitative approach, using public domain data from the Department of Informatics of the SUS. The monthly number of professionals who worked in the SUS, the number of outpatient procedures in each category and the projection of residents from zero to thirteen years old to normalize it were retrieved. Data were compared by pre-pandemic (2018-2020) and pandemic (2020-2022) periods with a significance level of 5%. Results: There was a significant reduction in the monthly number of outpatient procedures performed in the SUS by pediatricians in the first and second pandemic year of COVID-19 when compared to the pre-pandemic period (p <0.001 e 0.002, respectively). This reduction represents a median percentage reduction of -57.1% (CI95% -51.3%, -71.7%) in the first and -22.3% (CI95% -0.55%, -31.5%) in the second pandemic year. Regarding pediatric dentists, a significant reduction was observed only between the pre-pandemic period and the first pandemic year (p <0.001), representing -82.0% (CI95% -73.4%, -93.6%). Moreover, a significant, positive and moderate correlation was observed between the productivity of both professional categories in the SUS throughout the investigated period (p < 0.001, ρ = 0.744). Conclusion: The COVID-19 pandemic negatively affected the provision of specialized medical and dental outpatient care for children in the SUS.
An Intensive Exercise Program Using a Technology-Enriched Rehabilitation Gym for the Recovery of Function in People With Chronic Stroke: Usability Study
Authors: Kerr Andy , Keogh Maisie , Slachetka Milena , Grealy Madeleine , Rowe Philip
Published: June 2023

Background

Rehabilitation improves poststroke recovery with greater effect for many when applied intensively within enriched environments. The failure of health care providers to achieve minimum recommendations for rehabilitation motivated the development of a technology-enriched rehabilitation gym (TERG) that enables individuals under supervision to perform high-intensity self-managed exercises safely in an enriched environment.

Objective

This study aimed to assess the feasibility of the TERG approach and gather preliminary evidence of its effect for future research.

Methods

This feasibility study recruited people well enough to exercise but living with motor impairment following a stroke at least 12 months previously. Following assessment, an 8-week exercise program using a TERG (eg, virtual reality treadmills, power-assisted equipment, balance trainers, and upper limb training systems) was structured in partnership with participants. The feasibility was assessed through recruitment, retention, and adherence rates along with participant interviews. Effect sizes were calculated from the mean change in standard outcome measures.

Results

In total, 70 individuals registered interest, the first 50 were invited for assessment, 39 attended, and 31 were eligible and consented. Following a pilot study (n=5), 26 individuals (mean age 60.4, SD 13.3 years; mean 39.0, SD 29.2 months post stroke; n=17 males; n=10 with aphasia) were recruited to a feasibility study, which 25 individuals completed. Participants attended an average of 18.7 (SD 6.2) sessions with an 82% attendance rate. Reasons for nonattendance related to personal life, illness, weather, care, and transport. In total, 19 adverse events were reported: muscle or joint pain, fatigue, dizziness, and viral illness, all resolved within a week. Participants found the TERG program to be a positive experience with the equipment highly usable albeit with some need for individual tailoring to accommodate body shape and impairment. The inclusion of performance feedback and gamification was well received. Mean improvements in outcome measures were recorded across all domains with low to medium effect sizes.

Conclusions

This study assessed the feasibility of a holistic technology-based solution to the gap between stroke rehabilitation recommendations and provision. The results clearly demonstrate a rehabilitation program delivered through a TERG is feasible in terms of recruitment, retention, adherence, and user acceptability and may lead to considerable improvement in function, even in a chronic stroke population.

International Registered Report Identifier (IRRID)

RR2-doi.org/10.3389/fresc.2021.820929
Using Action Research and a community-academic partnership to understand clinical trial participation: a patient-centered perspective (Preprint)
Authors: Santarossa Sara , Baber Michele , Hussein Janine , Oley Chrystal , Slangerup Kristen , Murphy Dana , Kippen Karen E
Published: June 2023

BACKGROUND

Clinical trials that are patient-centered appear to be more successful (e.g., clinical outcomes, improved communication, mutual empowerment, changed attitudes), thus, action research may be a field of importance.

OBJECTIVE

The current study explores the Formation and Execution of Activities phases of a community-academic partnership (CAP).

METHODS

Members consisted of industry stakeholders, a healthcare/academic institution, and patients/families with lived experiences as cancer survivors and/or caregivers. Retrospectively, CAP members described the facilitating and/or hindering factors present in the partnership development. A document review process was used. Field notes from CAP meetings (N = 3), which focused on perceptions of participation in clinical research as a treatment option, were analyzed using a thematic approach.

RESULTS

Seven facilitating and three hindering factors were present. Interpersonal (vs. operational) processes were referenced as influential facilitating factors more often. Themes that emerged included ‘trials as a treatment option’, ‘leaving a legacy’, and ‘timing is critical.’

CONCLUSIONS

This study provides a patient-centered perspective on barriers/challenges of clinical research and how to improve future perceptions.
Demographic, Clinical, and Quality of Life Profiles of Older People With Diabetes During the COVID-19 Pandemic: Cross-Sectional Study (Preprint)
Authors: Sousa Fabianne , de Araujo Lucianne Nascimento , de Oliveira Tainá Sayuri Onuma , Gomes Mateus Cunha , Ferreira Glenda , Aben-Athar Cintia , da Silva Silvio Eder Dias , Cruz Ramos Aline MP , Rodrigues Diego Pereira
Published: June 2023

BACKGROUND

Diabetes mellitus, one of the main diseases that affects the Brazilian population older than 60 years, is defined as a divergent group of metabolic disorders that present a high level of glycemia (hyperglycemia), causing damage to various organs and systems of the body, including the heart, kidneys, eyes, and nervous system. It is believed that in 2025, in Brazil alone, there will be more than 18.5 million individuals diagnosed with diabetes mellitus. Therefore, it is important to know the individuals’ quality of life in the context of life and culture.

OBJECTIVE

This study aimed to assess the demographic, clinical, and quality of life profiles of older adults with diabetes during the COVID-19 pandemic in a university hospital complex in the northern Amazon region.

METHODS

We conducted a cross-sectional, exploratory, noninterventional, descriptive, and analytical study using a nonrandom sample of 54 older people diagnosed with diabetes mellitus at the geriatrics outpatient clinic of the medium and high complexity university hospital in the western Brazilian Amazon between 2020 and 2022. We used 3 instruments, namely, a sociodemographic questionnaire, a clinical conditions questionnaire, and Diabetes-39. Qualitative data were described using absolute and relative frequencies. The Kolmogorov-Smirnov normality test was applied, and the z test was used for inferential analysis. SPSS software (version 27) was used for data analysis, and the significance level was 5%.

RESULTS

Of the 54 interviewees, the majority were women, married, retired, and had a good quality of life. Of these, 48.1% (n=26) were infected by COVID-19, 61.5% (n=16) of whom progressed to long COVID, presenting with fatigue or muscle weakness. As for the quality of life, the “social overload” (P<.001) and “sexual functioning” (P<.001) dimensions had with low scores compared to the “energy and mobility” (P=.005), “diabetes control” (P<.001), and “anxiety and worry” (P<.001) dimensions. Quality of life was negatively impacted in the “anxiety and worry” dimension. Among those affected by COVID-19, most progressed to long COVID; however, there was a lack of data on this theme in the population of older people with diabetes.

CONCLUSIONS

The majority of interviewees progressed to long COVID, with their quality of life negatively impacted in the “anxiety and worry” dimension, reflecting that health actions prioritizing mental health should be implemented by health professionals.
Color Stability During Retail Display Differs Among Muscles in Pork
Authors: Barkley Kayla E. , Boler Dustin D. , Harsh Bailey N.
Published: June 2023

The objectives of this study were to determine differences in color stability among pork muscles and whether changes in color measurements for longissimus dorsi (LD) were related to changes for triceps brachii (TB) or psoas major (PM). The LD, TB, and PM from 20 pigs were aged in vacuum packages for 21 d, then fabricated into 3 chops per muscle. All chops from a single muscle were overwrapped, displayed for 5 d under constant lighting, and evaluated daily for instrumental color, myoglobin forms, and subjective visual discoloration. Chops were removed on day 1, 3, or 5 to measure oxygen consumption (OC) and metmyoglobin reducing activity (MRA). Data were analyzed using the MIXED procedure of SAS as repeated measures. Pearson correlation coefficients were determined using the CORR procedure. Over the 5-d display period, TB and PM chops had greater changes in a*, b*, chroma, 630/580 nm ratio, deoxymyoglobin, and oxymyoglobin compared to LD chops (display time×muscle interaction P≤0.01), but TB and PM did not differ from each other (P≥0.07). Conversely, LD had decreased OC and increased MRA on each display day compared to TB and PM (P<0.01). Using 20% discolored on day 5 of display as a threshold for acceptability, 85% of LD samples were considered acceptable whereas only 5% and 20% of TB and PM samples were considered acceptable, respectively. Changes in LD were correlated with TB and PM changes for redness (0.51≤r≤0.55; P≤0.02), and they trended toward a correlation with changes in TB and PM 630/580 nm ratio and hue angle (0.39≤r≤0.63). Chops from TB and PM were less color stable during display, but LD changes were not consistently correlated with changes in other muscles.
Relationships Among Initial Color or Biochemical Traits and Final Discoloration in the Pork Longissimus Dorsi, Triceps Brachii, and Psoas Major
Authors: Barkley Kayla E. , Boler Dustin D. , Harsh Bailey H.
Published: June 2023

The goal was to determine relationships between color or biochemical traits at the beginning of retail display (day 1) and final discoloration (day 5) in longissimus dorsi (LD), triceps brachii (TB), and psoas major (PM) and determine what combination of initial traits was most predictive of final discoloration in each muscle. Muscles from 20 pigs were aged in vacuum packages and fabricated to yield 3 chops per muscle. These 3 chops from the same muscle from a single pig were displayed together under constant lighting for up to 5 d. On day 1, all chops in a package were evaluated for visual dis-coloration, instrumental color, and myoglobin (Mb) forms. One chop on day 1 was evaluated for oxygen consumption (OC), metmyoglobin-reducing activity, and Mb content. Final visual discoloration and 630/580 nm ratio were evaluated on one chop from each muscle on day 5. Pearson correlation coefficients were compared between LD, TB, and PM using Fisher’s z test in SAS. Stepwise regression models were developed using the REG procedure. All initial traits were correlated to final visual discoloration and 630/580 nm ratio in TB and PM (|0.47|≤r≤|0.72|), except redness, day 1 630/580 nm ratio, OC, and Mb (P≥0.07). Final LD 630/580 nm ratio was correlated to initial lightness, redness, hue angle, deoxymyoglobin, and pH (|0.48|≤r≤|0.75|). Initial lightness and Mb (0.20≤partial R2≤0.21) were most predictive of final LD visual discoloration (R2=0.33). Yellowness was most predictive of 630/580 nm ratio for all muscles (0.32≤partial R2≤0.85). Correlations were generally stronger in TB and PM compared with LD but did not differ from each other (P≥0.17). In all muscles, color-stable chops were initially darker, were less yellow, and had lesser hue angles.
Gain Enhancement of Microstrip Patch Antenna for Wi-Fi Augmentation
Authors: Jyothi N. Krishna
Published: June 2023

Abstract: A wideband, compact and low profile microstrip patch antenna (MSPA) design for wireless fidelity and C-band considerations is very advantageous in various applications. The antenna proposed in this paper consists of a simple laterally inverted Swastik-shaped patch with the microstrip line fed and a rectangular ground plane. The antenna has patch dimension of 15mm×12mm, substrate dimension of 20mm×20mm overall size, prototyped on FR4 material of excellent physical and electrical properties, thickness of 0.5 mm and a dielectric constant of 4.4. According to the software simulation results, the proposed MSPA displays remarkable return loss and voltage standing wave ratio (VSWR) and operates at the Wi-Fi frequency of 5 GHz. In addition to this, it may also be operated in the frequency range of 4-8 GHz. The results obtained from the measurements are similar to the fabricated antenna after testing using the vector network analyzer (VNA).
Study on Coal Mine Safety Monitoring and Alerting System Using IOT
Authors: Srivalli Dr. G.
Published: June 2023

Abstract: A coal mine safety monitoring and alerting system using IoT can help improve safety in coal mines by providing realtime monitoring and alerting of hazardous conditions. The system can use various sensors and devices to monitor parameters such as gas concentration, temperature, humidity. The data from these sensors can be collected, processed, and analyzed using an IoT platform to provide insights into the condition of the mine. The system can also incorporate a range of alerting mechanisms to notify mine workers and supervisors of any hazardous conditions For example, the system can use audio and visual alarms, mobile notifications, and even automatic shutdown of machinery in case of danger. The system utilizes various sensors and devices to monitor parameters such as gas concentration, temperature, humidity, and collects, processes, and analyzes the data using an IoT platform. The system aims to reduce the risk of accidents and injuries to mine workers, increase productivity, and reduce downtime.
Tindak Tutur Komisif Politikus Pemenang Partai Pemilu di Indonesia Tahun 2019: Kajian Pragmatik
Authors: Yelmida
Published: June 2023

Penelitian ini bertujuan untuk mengetahui adanya tuturan komisif pada pidato politikus partai pemilu di Indonesia tahun 2019. Metode penelitian yang digunakan adalah metode kualitatif dengan pendekatan etnografi, fenomenologi, grounded theory, dan studi kasus. Hasil penelitian ini menunjukan:  1. Jenis tindak tutur komisif yang terdapat pada pidato politikus pemenang partai  pemilu di Indonesia tahun 2019  ditemukan jenis tindak tutur berniat, berjanji, dan, menawarkan. 2. Fungsi tindak tutur komisif politikus pemenang partai pemilu di Indonesia tahun 2019  terdiri atas 43 fungsi tindak tutur berniat  ditandai dengan penanda gramatikal akan . 38 fungsi tindak tutur berjanji ditandai dengan penanda gramatikal harus, akan pasti dan InsyaAllah. 3 fungsi tindak tutur menawarkan  ditandai dengan penanda gramatikal dapat, menawarkan. Tuturan bersumpah tidak ditemukan. Dengan demikian, kecenderungan yang paling banyak digunakan adalah tindak tutur janji yang komisif.
STRUKTUR DAN KAIDAH KEBAHASAAN TEKS TANGGAPAN DALAM BUKU TEKS WAHANA PENGETAHUAN BAHASA INDONESIA SMP KELAS IX
Authors: Miftahunnajah
Published: June 2023

Penelitian ini bertujuan untuk mengetahui kesesuaian dan ketidak sesuaian struktur dan kaidah kebahasaan teks tanggapan yang ada didalam buku teks wahana pengetahuan Bahasa Indonesia SMP kelas IX kurikulum 2013.Metode penelitian yang digunakan adalah deskriptif kualitatif dengan metode analisis isi, penelitian kualitatif yaitu yang mengkhususkan keakuratan data yang diperoleh bukan hanya banyak data yang didapat. Berdasarkan hasil yang diperoleh dari penelitian yang difokuskan pada teks tanggapan dalam buku teks wahana pengetahuan Bahasa Indonesia SMP kelas IX kurikulum 2013, diperoleh 6 teks tanggapan dan Kesesuaian struktur teks yang ditemukan dengan presentase terkait 3 bagian Struktur tanggapan yang terdiri dari evaluasi 100%, deskriptif 100% dan penegasan ulang 66%. Sedangkan ketidak sesuaian yang ditemukan hanya ada pada bagian struktur penegasan ulang dengan presentase 34%. Selanjutnya Kesesuaian kaidah kebahasaan yang ditemukan yaitu dengan presentase terkait 4 bagian kaidah kebahasaan yang ada dalam teks tanggapan meliputi kalimat kompleks 100%, konjungsi 100%, kata rujukan 66% dan juga pilihan kata 100%.Dengan ketidak sesuaian yang ditemukan hanya ada pada bagian kata rujukan yang presentase sebesar 34%.
Street art as a vehicle for environmental science communication
Authors: Thompson Blake , Jürgens Anna-Sophie , None BOHIE , Lamberts Rod
Published: June 2023

Street art is visual art in public spaces — public art — created for public visibility. Street art addresses a massive and extremely diverse audience: everyone in a city. Using a case study approach, this article explores: 1) the extent to which science-inspired environmental street art can be considered a vehicle for science communication in less tangible science contexts and institutional settings — on the street — and 2) the strategies that street artists deploy to communicate their environmental messages through large-scale painted murals. This article clarifies how street art can be understood as a means of creative grassroots environmental communication. It shows that, and how, street art can encourage agency in pro-environmentalism and help to develop our relationship with sustainability.
Issues of foundations and criteria of law: criticism of the theory of social rules and conventional rule of recognition in “early” R. Dworkin’s doctrine
Authors: Kasatkin Sergei N.
Published: June 2023

The article investigates the doctrine of an American jurist, Ronald Dworkin, presented in the essay “Social Rules and Legal Theory” (1972) and considered as a stage in his large-scale polemics with legal positivism. In this doctrine the author criticizes the theory of “social rules” and the conventional “rule of recognition”, which is basic for his opponents. The theory requires an agreed unity of practice and defends the controversial character and moral engagement of normative grounds and criteria of law, their priority and autonomy against community practices. The relevance of the topic is due both to the fundamental nature of the Dworkin - positivists dispute, and peculiarities of the 1972 doctrine, which formed a number of its “cross-cutting” elements. The article is aimed at systematization and assessment of the 1972 doctrine, relies on the texts by its author, his opponents and researchers, and uses various tools, primarily the ideological and historical method, focused on explication of views and issues developing in the history of thought. The study results are generalization of original components of R. Dworkin’s 1972 doctrine, its localization within the dispute between the author and positivists and discerning its ideological and historical implications. Summing up the article emphasizes a stimulating role of the 1972 doctrine for evolution of the rival approaches, as well as its potential for the philosophy of law, associated with R. Dworkin’s problematization of a link between normativity and facticity in law, linguistic-analytical idea of a rule as a practice, and conventionalist account of foundations of law which decenters normative disagreements.
Concession policy of the Soviet state: implementation mechanism
Authors: Nemytina Marina V. , Krasnov Alexey B.
Published: June 2023

The article analyzes the experience of the concession policy implementation by the RSFSR and the USSR during the 20s of the twentieth century and the approaches used in its framework, which allowed solving simultaneously a wide range of tasks related to the rise of the domestic economy and overcoming foreign policy isolation. This experience of the Soviet state can be used to solve the challenges the Russian Federation is facing today. The authors substantiate that the concession policy of the Soviet state was a rationally constructed mechanism able to solve a number of tasks. 1) Creation of foreign concessions in the Soviet country contributed to withdrawal from the diplomatic blockade declared by Western countries. 2) Through the concession policy the obligations of the Russian Empire to foreign investors were renewed in the conditions of a socialist economy. 3) By creating concessions the Soviet government headed by V.I. Lenin attracted the material and technological resources of the European countries and the USA for the development of the economy of the Soviet country. 4) At concession enterprises models of industrial relations with a high level of labor organization and living conditions of workers were formed at the expense of foreign investors, which then had to be introduced everywhere. 5) The concession policy covered the national suburbs and contributed to unification of the economic potential of the republics as part of the USSR. The analysis of the legal regulation of concession relationships carried out in this article gives reason to suppose that the concession policy of the Soviet state should not be reduced to the NEP because its implementation started earlier. In fact, it was launched with the adoption of the Decree of the Council of People’s Commissars of November 23, 1920 On General Economic and Legal Conditions for Concessions and within its framework a range of tasks that went far beyond the economic recovery envisaged by the NEP through private law principles was solved. Attention should also be paid to the constitutional nature of the regulation of concession legal relations, which was determined by the “Treaty on the USSR Foundation of 1922” and the Constitution of 1924.
United States of America and the pandemic: issues of legal regulation in combating COVID-19
Authors: Latypova Natalia S.
Published: June 2023

The pandemic period in the United States has become a test of the strength of many state mechanisms, raised the question of the limits of the extraordinary powers of the President and governors and effectiveness of the public health system. The reasons why one of the most prosperous countries in the world has become the most affected state by the pandemic largely lie in the sphere of public administration system and historically established precedents for expanding the powers of the executive branch in times of emergency. The aim of the study is to identify the foundations of constitutional and legal regulation in combating the consequences of the pandemic in the United States and to trace correlations between peculiarities of distribution of powers in the field of public security and effectiveness of measures to counter the COVID-19 spread. One of the tasks is to identify both advantages and disadvantages of the US political structure in the context of countering the nationwide threat. The historical method of research allowed to determine the specifics of the extraordinary powers of the US President, while the specific legal method was used as the basis for analyzing the structure and powers of legislative and executive authorities along with comparative legal, system-structural and functional approaches. In the fight against the pandemic, the mechanism of public administration in the United States has shown its inability to counter threats of a nationwide nature. In many ways, this situation is explained by peculiarities of the legislative regulation of the healthcare sector, transferred to the autonomous regulation of state authorities, a disparate system of legal regulation of emergency response, as well as the very modest capabilities of the head of state in responding to epidemiological threats. The study allows to conclude that there is a correlation between the features of the public administration system in the United States, its legislative regulation and the negative consequences of the COVID-19 pandemic caused by uncoordinated actions of federal and regional government authorities.
The concept and features of administrative regulations as a source of Russian law
Authors: Nazaykinskaya Varvara A.
Published: June 2023

This article is a continuation of a previously published article on administrative regulations as a type of public administration acts. The purpose of this article is to identify the features of administrative regulations as a source of Russian law. It investigates existing shortcomings in the development and adoption of administrative regulations and proposes possible ways of their elimination. The study uses both general scientific and special research methods: analysis and synthesis, induction and deduction, comparative and formal legal methods. The conducted research allows to identify the specifics of administrative regulations as sources of Russian law, to outline the place and the role of these regulatory legal acts in the legal system of Russia. The author gives the definition of administrative regulations, reflecting their most important and essential features. The article studies such negative aspects as the practice of approving administrative regulations, which are codified departmental acts, by simple acts - orders. Also, to date, administrative regulations are not subject to regulatory impact assessment, which is also recognized as a negative phenomenon. The results of the study can contribute to improving the processes of developing and adopting administrative regulations and enhancing the level of legal technology of these regulatory legal acts.
Public procurement in Russia: concept and content
Authors: Kikavets Vitaly V.
Published: June 2023

Based on the analysis of foreign and national legal acts, scientific works and research of domestic and foreign scientists, the article substantiates the relevance of the concept “public procurement” and reveals its content. The outcome of the research on public procurement as a system of legal relations allows the author to verbalize its definition. Public procurement should be understood as a system of legal relations where one party is an authorized representative of public authority who purchases goods, works, and/or services at the expense of the relevant budget in order to realize public interest. The characteristic features of public procurement are highlighted, and the most significant functions of public procurement are substantiated, including social, regulatory, reproductive, innovative, stimulating, and cost optimization. The author offers classification of the main subjects of public procurement, involving authorized representatives of public authorities (entities authorized to regulate and control public procurement, to centralize and conduct joint bidding, as well as all customers), business entities (suppliers, contractors) and derivative entities (banks and credit organizations, electronic trading platforms, specialized organizations). It is emphasized that in order to increase the efficiency of budget spending and optimize the financial support of public procurement, a number of derivative entities may be abolished. The article sustains that legal relations in public procurement are subject to regulation by the norms of financial, administrative, and civil law. It notes that legal relations in public procurement regulated by the norms of civil law (contractual legal relations) arise exclusively after the relations regulated by the norms of public law. It outlines the legal characteristic of the revealed legal relations and justifies the necessity of considering the priority of the norms of public law.
Legal support for the development of sustainable and secure information and telecommunications infrastructure
Authors: Belousov Andrey L.
Published: June 2023

The relevance of the work is due to the need to adapt regulatory mechanisms to the actively developing digitalization processes. On the other hand, in the context of growing cyber threats and increasing dependence of public relations on information and telecommunications technologies, the directions for the development of legislation that ensure stability and security of the relevant infrastructure are subject to a certain rethinking in the legal aspect. The subject of the study is the legal support for the development of a sustainable and secure information and telecommunications infrastructure. The purpose of the work is to identify key areas for improving legal regulation in the field of functioning and development of sustainable and secure information and telecommunications infrastructure. The study applies methods of analysis, synthesis and comparison, as well as literal and systematic interpretation of the norms of the current legislation in the field of functioning and developing sustainable and secure information and telecommunications infrastructure. Finally, conclusions are formulated regarding the need for the development of legal regulation in this area. The research outlines the specific directions for changing the legal field, which ensure the sustainable development of information and telecommunications infrastructure in the Russian Federation.
SGLT2 Inhibitors in the Prevention and Treatment of Cardiovascular Disease
Authors: Rheaume Michael , Khetan Aditya , Pigeyre Marie
Published: June 2023

Over the last decade, sodium-glucose transport (SGLT2) inhibitors have become one of the most exhaustively studied classes of medications for cardiometabolic diseases. Although multiple trials have established their benefit, one of the crucial tasks of the medical community is to accelerate their effective adoption into clinical practice by identifying the most appropriate patient population who could benefit from it. To date, this class of medications is indicated in patients with symptomatic (NYHA class II-IV) congestive heart failure with preserved or reduced ejection fraction, chronic kidney disease, or type 2 diabetes with cardiovascular (CV) risk factors. This article focuses on best implementing these medications into clinical practice and reviews their proposed mechanisms of action.
RésuméAu cours de la dernière décennie, les inhibiteurs du transport du sodium et du glucose (SGLT2) sont devenus l’une des classes de médicaments les plus étudiées dans le traitement des maladies cardiométaboliques. Bien que de multiples essais aient établi leur bénéfice, l’une des tâches cruciales de la communauté médicale est d’accélérer leur adoption effective dans la pratique clinique en identifiant la population de patients la plus appropriée qui pourrait en bénéficier. À ce jour, cette classe de médicaments est indiquée chez les patients souffrant d’insuffisance cardiaque congestive symptomatique (classe II-IV de la NYHA) avec fraction d’éjec-tion préservée ou réduite, de maladie rénale chronique ou de DT2 avec facteurs de risque cardiovasculaire (CV). Cet article se concentre sur la meilleure façon de mettre en œuvre ces médicaments dans la pratique clinique et fournit un examen de leurs mécanismes d’action proposés.
Spontaneous Intracranial Hemorrhage and Oral Anticoagulation
Authors: Duquet-Armand Marie , Bouziane Amine , Arruda Alexandra , Denault Jean-Simon , Routhier Annie , Cusson Tasha , Halwagi Antoine , Williamson David , Perreault Marc , Lordkipanidze Marie , Létourneau-Guillon Laurent , Thiboutot Zoé
Published: June 2023

Background: Canadian data on intracranial hemorrhage (ICH) associated with oral anticoagulation is limited. Objectives: Primary study outcomes were baseline hematoma volumes and in-hospital mortality in patients with ICH associated with direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs). Second-ary outcomes included the use of four-factor prothrombin complex concentrate (4f-PCC).
Methods: Retrospective cohort study of patients with ICH associated with oral anticoagulation in three ter-tiary care hospitals in Montreal, Canada, between 2011 and 2018.
Results: Twenty-nine patients were receiving DOACs and 114 patients were under VKAs. Median baseline hematoma volumes were similar, 14.8 ml [5.7–42.8] in the DOAC group and 15.6 ml [5.9–38.1] in the VKA group (p = 0.91). In-hospital mortality rate was 34.5% in the DOAC group and 48.2% in the VKA group (p = 0.26). Only 17 patients (58.6%) in the DOAC group received 4f-PCC.
Conclusion: Our study did not demonstrate significant differences in outcomes of ICH associated with DOACs versus VKAs. Management approaches were variable.
RésuméContexte: Il existe peu de données canadiennes sur l’hémorragie intracrânienne (HIC) associée à la prise d’anticoagulants par voie orale.
Objectifs: Les critères d’évaluation principaux de l’étude sont le volume initial de l’hématome et la mortalité à l’hôpital chez des patients présentant une HIC associée à la prise d’anticoagulants oraux directs (AOD) par rapport à la prise d’antagonistes de la vitamine K (AVK). Les critères d’évaluation secondaires comprennent l’utilisation d’un concentré de complexe prothrombique à quatre facteurs (4f-PCC pour four-factor prothrombin complex concentrate).
Méthodologie: Étude de cohorte rétrospective portant sur des patients présentant une HIC associée à la prise d’anticoagulants oraux dans trois hôpitaux de soins tertiaires de Montréal (Canada) entre 2011 et 2018. Résultats: Au total, 29 patients prenaient des AOD et 114 des AVK. Les volumes médians des hématomes au départ sont semblables, soit de 14,8 ml (de 5,7 à 42,8) dans le groupe des AOD et de 15,6 ml (de 5,9 à 38,1) dans le groupe des AVK (p = 0,91). Le taux de mortalité à l’hôpital est de 34,5 % pour le groupe des AOD et de 48,2 % pour celui des AVK (p = 0,26). Seuls 17 patients (58,6 %) du groupe des AOD ont reçu le 4f-PCC.
Conclusion: Notre étude ne montre aucune différence importante dans les résultats concernant l’HIC associée à la prise d’AOD par rapport à la prise d’AVK. Les méthodes de prise en charge sont variables.