bluuebunny/crossref_metadata_2025 huggingface dataset:
INDIVIDUAL SPONTANEITY AND THE POSSIBILITY OF COMMUNITY IN MEAD’S SOCIAL PSYCHOLOGY
Authors: Gürsoy Ali Özgür
Published: July 2024

The central question of the present study is how to understand the spontaneity of the social self in George H. Mead’s account of the genesis and structure of the self. Its argument develops in three stages. First, I provide a brief discussion of the notion of the self in relation to social existence in Hegel in order to highlight some salient features that will prefigure some of the claims that Mead makes. Second, I discuss Mead’s theory in greater detail in order to emphasize the role of communication and ‘attitude-taking’ in the constitution of the self. These factors comprise what is particularly original in Mead’s account. Finally, I offer an evaluation of Mead’s key claims in the context of certain questions concerning the relationship between the individual and community. I think that Mead provides a sound scheme by means of which we can understand the constitution of the self as a social phenomenon and communities as dynamic systems susceptible to transformation in response to individual and/or group action, i.e., without reifying communities. However, the dynamics of social change, for the most part in terms of ‘adaptation’ in Mead’s account, needs some modification, if we want to understand those periods of social upheaval during which the continuity between the ‘old’ and the ‘new’ seems minimal.
On the Development of Arctic Research through Scientometrics
Authors: Terekhov A. I. ,   Central Economics and Mathematics Institute of RAS
Published: July 2024

There are still few Russian studies on quantitative measurements of Arctic science that could help create a holistic picture of developing research, compare the contributions of individual countries, and assess Russia’s scientific potential. The performed scientometric analysis partly fills this gap, relying on multiple sources: bibliographic databases Web of Science Core Collection and DIMENSIONS; grant databases of Russia, the USA and Germany. The analysis revealed: 1) the fast growth of Arctic publications in the period 1980–2020 with an average annual rate of 5 % after 2008, which is similar to some high-tech fields; 2) increasing globalisation of research performed by scientists from more than 100 countries; 3) changes in Arctic research interests, including long-term trends (socialisation of research, decreasing share of works on geology and physical geography) and fast new trends (increasing share of publications on economics and technologies of industry 4.0). According to calculations, Russia is third among countries in terms of the number of Arctic publications in the Web of Science Core Collection database, significantly contributing to highly cited papers; however, this contribution may be negatively affected by a decline in the share of Russian publications with international co-authorship. Thanks to its traditionally strong position, the Russian Academy of Sciences remains the leading centre of global Arctic research; within the country, it promotes Arctic science through its regional branches and institutes, as well as supports the intensification of university studies. The abstracts of selected 2023 Arctic grants reflect the topics of some future publications; for example, their analysis showed different attitudes towards the role of the climate factor in Arctic research: excessive focus of projects supported by foreign funds and a more balanced approach in Russian projects.
Problems and Approaches to Identifying Agglomeration Boundaries in the Russian North and Arctic
Authors: Kozhevnikov S. A. ,   Vologda Research Center of RAS, Patrakova S. S. , Voroshilov N. V. ,   Vologda Research Center of RAS,   Vologda Research Center of RAS
Published: July 2024

Urban agglomerations are currently considered by both scientists and practitioners of public administration. However, the issue of identifying the actual boundaries and creating tools for the development of so-called “second” – and “third-tier” agglomerations, with cores in large and medium-sized cities, remains understudied. Nevertheless, such agglomerations can become development drivers for territories outside the settlement area, primarily in the North and the Arctic. The article aims to determine the composition and boundaries of northern and Arctic agglomerations of Russia considering their specificity. The study presents the authors’ methodological approach to the delimitation of agglomerations combining traditional (isochrones of transport accessibility, gravitational methods) and modern tools (GIS technologies, big data analytics of social networks). As a result, the composition and boundaries of three northern/Arctic agglomerations with cores in Arkhangelsk, Surgut, Norilsk were identified, their specific characteristics were highlighted: the actual borders often do not meet strict traditional criteria of delimitation, particularly, the 1.5-hour isochrone of transport accessibility of the core city due to the weakened effect of geographical proximity; according to the development criterion of the settlement system, two of them (Surgut, Arkhangelsk) can be attributed to agglomerations; despite the underdeveloped settlement framework (the development coefficient is less than 2.7) and a growing share of the core city population in the total population, satellite areas increasingly become economic centres of gravity of agglomerations. The study substantiated the expediency of applying a flexible approach to the delimitation of borders and selecting tools for the development of urban agglomerations, taking into account formation factors and their economic and geographical location, specifically in the North and non-North projections. Further research will involve an in-depth assessment of localisation and urbanisation effects of the studied agglomerations.
Enabling STE(A)M in Sustainability Education Through Dialogic/Dialectic Reconciliation
Authors: Schudel Ingrid
Published: July 2024

In the context of a need for finding and enabling alternatives to unequal and extractivist perspectives on development, growth, and human well-being, this positioning paper explores possibilities for STEAM (science, technology, engineering, arts, and mathematics) education with an education for sustainable development focus that counters disciplinary alienations particularly between the arts and the STEM (science, technology, engineering and mathematics) disciplines. The paper argues that unnecessary alienations between cultural-emblematic and mathematical-logical epistemes, especially those linked to narrow interpretations and restricted developments in dialogism and dialectics, respectively, are influenced by restricted understandings of epistemological, ontological, and praxiological philosophical drivers in meaning making and responsive action. In response, the paper develops a series of philosophical principles that, it argues, could usefully underpin STEAM education practices. These are a) iterations of epistemological expansion and contraction (in response to monologic meaning making), b) an expansive and deepening ontology (in response to ontological collapse in describing the world), c) critical and judgmental rationality (finding a middle ground between radical relativism and dogma), and d) concrete utopianism (in response to idealism and additive holisticism). The emergence of the four philosophical principles is developed through illustrative examples of a broad range of arts (fine art, performance art, photography, film, poetry, prose, and music).
Uso e conservação de subprodutos da indústria de processamento de uvas para fins alimentícios
Authors: Duarte Stephany Gonçalves , Valerio Gabriel Batezati Rabelo , Costa Sérgio Marques , Arana Alba Regina Azevedo , Uliana Maíra Rodrigues
Published: July 2024

O Brasil é um dos maiores produtores mundiais de resíduos de frutas e esses resíduos vêm especialmente das indústrias de processamento de alimentos, o que pode resultar em problemas ambientais. Assim, muitos estudos têm sido conduzidos para investigar o valor nutricional e funcional dos resíduos de frutas, sugerindo usos alternativos. As uvas são uma ótima fonte de compostos antioxidantes; uma grande quantidade de resíduos é gerada durante seu processamento industrial para obtenção de vinhos, sucos, geleias, etc. Tais resíduos podem conter quantidades significativas de compostos antioxidantes que despertam interesse científico devido aos possíveis benefícios para a saúde humana. Este estudo teve como objetivo (I) caracterizar o resíduo de uva de uma indústria de geleias; (II) testar técnicas de secagem para obtenção de farinha a partir desse resíduo (secagem em forno e liofilização). Diferentes temperaturas e tipos de secagem foram testados (forno: 45, 65, 85 e 105 °C; e liofilização). Os resíduos e as amostras secas (farinhas de bagaço de uva) foram analisados quanto às propriedades físicas, químicas, nutricionais e funcionais. Os resultados mostram que o bagaço de uva possui compostos e características que poderiam ser valiosos na produção de alimentos como fonte de açúcares, antocianinas e proteínas. A caracterização das farinhas mostrou que após a secagem em forno a 80 ºC, em geral, a maioria dos compostos bioativos é degradada, enquanto o processo de liofilização e a secagem em baixas temperaturas mantêm melhor as características da farinha, quando comparados com o resíduo antes do processo de secagem. Em resumo, o bagaço de uva pode ser utilizado na produção de alimentos, melhorando as características físicas, químicas, nutricionais e funcionais dos produtos fabricados usando sua farinha.
Pseudo-algebraically commutative fields of quasi-fourier–smale curves and hyperbolic topological spaces
Authors: Olcay Akman
Published: July 2024

Let us suppose we are given a category Σ. Is it possible to construct commutative vectors? We show that I < ∞. It is essential to consider that C may be geometric. A useful survey of the subject can be found in [1].
The dark side of screens: Exploring impairment with the iRAT framework
Authors: Mucho Memes , Carlsen Lusterfuck , Daniele Eatheater
Published: July 2024

This paper introduces the iRAT model, an extension of the existing RAT framework, to comprehensively evaluate the integration of digital media in educational settings. While the traditional RAT framework focuses on Replacement, Amplification, and Transformation, the iRAT model includes a fourth category: Impairment. This new category addresses the potential negative impacts of digital media use, such as unnecessary app usage, distractions from learning objectives, lack of pedagogical integration, and resource wastage. The study employs a mixed-methods approach, including participatory observation, lesson plan evaluation, expert think-aloud protocols, and AI-driven scenario identification, to validate the iRAT model. Findings highlight the importance of considering both positive and negative aspects of digital media integration, suggesting that future research should adopt the iRAT framework for a balanced evaluation. This study closes a significant research gap and challenges the overly optimistic view of digital media in education, advocating for a more critical perspective.
READDI protocol: Crystallisation of CHIKV nsP3 macrodomain v1
Authors: Aschenbrenner Jasmin , Marples Peter , fairhead michael , Schutzer de Godoy Andre , Fearon Daren
Published: July 2024

Chikungunya virus (CHIKV) causes severe fever, rash and debilitating joint pain that can last for months or even years. Millions of people have been infected with CHIKV, mostly in low- and middle-income countries, and the virus continues to spread into new areas due to the geographical expansion of its mosquito hosts. The crystallization protocol and buffer conditions used to obtain reproducible Chikungunya Virus nsP3 macrodomain crystals suitable for XChem fragment screening.
Adverse Childhood Experiences, Substance Use, and Poor Mental Health Among the U.S. Adult Population
Authors: Mugoya George C. T. , Muchiri Steve M. , Ogongi Wanja , Gitau Mary , Mkuu Rahma , Cook Ryan , Lu Yu
Published: July 2024

Adverse childhood experiences (ACEs) are linked to various lifelong negative outcomes. However, there is little counseling literature on the effects of ACEs on adult mental health. Utilizing the 2021 Behavioral Risk Factor Surveillance System dataset, we examined individual ACEs and cumulative ACEs scores to quantify the relationship between ACEs and behavioral and mental health outcomes. Findings showed that 60.9% of the participants experienced at least one ACE, with nearly 1 in 6 participants reporting four or more ACEs. Childhood emotional abuse was the most prevalent form of ACE reported. Multiple logistic regression analyses adjusting for sociodemographic covariates showed that reporting any of the ACEs was significantly associated with heavy alcohol use, marijuana use, and poor mental health. Furthermore, a graded dose-response relationship was found between cumulative ACEs scores and outcome variables. The findings highlight the importance of consciously screening and considering ACEs to better assist clients with presenting behavioral and mental health issues.
Retrospective of the Emergence and Development of Departmental Procedural Control as an Element of the Mechanism for Correcting Investigative Errors. Case Study of the Activities of Revolutionary Tribunals in 1917–1922
Authors: Bukharina N. P.
Published: July 2024

Development in 1960–1990 of departmental procedural control as the theory of criminal procedure understand it now would have been impossible without the tribunal justice in 1917–1922. The use of the historical legal method made it possible to analyze the dynamics of the functions of revolutionary tribunals with general competence, to study their relationships with emergency commissions and other bodies of inquiry and preliminary investigation. The results of the study showed that in 1917–1922 the tribunals not only administered justice for the most serious crimes, but also performed the function of identifying investigative errors, for which they were endowed with the appropriate procedural powers. The author draws conclusions about the degree of effectiveness of the implementation of these powers in the conditions of permanent reform of tribunal justice based on a study of statistical data from the mentioned period. An analysis of the normative legal acts that regulated the activities of revolutionary tribunals allows us to say that in 1917–1922 departmental procedural control was not differentiated and its development was inseparable from the evolution of judicial and departmental control, and later — prosecutorial supervision.
Fire Experts Certification: Trends, Issues, Proposals
Authors: Karpov S. Yu. , Ponimaskin A. Ya.
Published: July 2024

The paper discusses issues related to the certification of forensic fire experts in forensic institutions of the federal fire service of the Ministry of the Russian Federation for Civil Defence, Emergencies and Elimination of Consequences of Natural Disasters (EMERCOM of Russia). Particular attention is given to the staffing and balance of experts who have the right to carry out expert examination under competencies approved by the EMERCOM of Russia. It is shown that in many expert departments there are no experts in most of the fields of forensic fire examination approved by the EMERCOM of Russia. The authors draw attention to the need to unify the specializations of forensic fire examinations with other expert institutions and organizations. The number of specializations in forensic fire examination and the improvement of training of fire experts are discussed. It is proposed to reduce the number of specializations in forensic fire examination approved as the competence requirements for employees of the federal fire service of the EMERCOM of Russia for «Forensic fire examination» specialization. In order to increase the efficiency of forensic expert activities, the authors recommend creating and consistently maintaining a database of forensic fire experts in Russia.
The Unity and Struggle of Opposites in Concepts of the Right of Nations to Self-Determination Developed by V.I. Lenin and V. Wilson
Authors: Kagramanov A. K.
Published: July 2024

The paper deals with the conflict between the concepts of self-determination stated by V.I. Lenin and V. Wilson, which determined the formation of a new world order from the beginning of the 20th century until the end of the Second World War, which is based on the political and legal idea of self-determination.In 1914, Vladimir Lenin put forward the concept of self-determination in the article «On the right of nations to self-determination», which was dedicated to the confrontation between the «oppressive» and «oppressed» nation with the right to secede the latter and «form a national state». This concept was taken up by American President Woodrow Wilson. He used it as a basis for the «Fourteen Points» when addressing the US Congress in 1917 as a political formula and legal justification for the US entry into the First World War, the fragmentation of Europe into nation states and the increase in political influence.The author concludes that the principle of self-determination, developed by Lenin and further developed by Wilson, was based on various ideological premises and initially had a diametrically opposite meaning. Whereas in Lenin’s work the emphasis was on the creation of a sovereign state up to the point of secession and/or annexation to another state, but under the protection of international law, then for Wilson self-determination was almost identical to «government of the people» or «government by consent», with the possibility of exerting political influence on a self-determined nation and justifying military conflicts with the participation of the United States in Latin America.Exploring the conceptual component of ideas, foreign policy documents of Soviet and American diplomacy, the author, based on an analysis of the world order that emerged after the First World War and the rapid process of national liberation movements and decolonization, concludes about the stunning influence of the Leninist formula on the emergence of new states in Europe, Asia, and others regions of the world, as well as for the return of the national outskirts of the former Russian Empire lost as a result of the Brest-Litovsk Treaty.
Hybrid Model for Conducting Multiple Citation Analysis Operations Using the Same Citation Data
Authors: Meena Bhagwan Sahay , Majumder Sharmila Bose , Rathore Nemi Chandra , Jain Neeraj
Published: July 2024

This study proposes a hybrid model, which can be used for conducting various citation analysis operations over a set of research works/papers interconnected with each other through their citations and references. Citation analysis of papers becomes important while evaluating their role and influence in a particular field and understanding their relation and connectivity of content with other important documents in the same field. The citation analysis methods can further be used for tracing the relationship between domains, keywords, and many other relative factors, based on the criteria considered for citation analysis operation. The research in the field of citation analysis, traditionally focussed on developing new citation analysis methods for better evaluation or ranking of the papers. This paper proposes a model, where multiple existing citation analysis operations can be implemented in a single platform. The proposed model calculates the result for co-citation analysis, bibliographic coupling, and citation density analysis. The process involved in the development of this model is discussed in detail in the later part of the manuscript. The process is based on computational coding, and hence special attention needs to be paid to the proper arrangement of papers in tabular form, based on the information of their year of publication and their citation network data. An algorithm for the model has been proposed in the later part of the manuscript that is based on the code formulated to find the relative data for conducting the operations.
Digital Literacy as a Tool for Enhancing Access and Utilization of Digital Information - A Case Study in Kenya
Authors: Tenya A. N. , Maina J. C. , Awuor F. M.
Published: July 2024

Technology is pervading every aspect of our lives. Therefore, the skills to navigate and accomplish tasks through technology have to be developed. Digital literacy is a tool for promoting effective access to and utilisation of digital information. This study investigates the adequacy of digital literacy skills among academic staff in selected public universities in Kenya. Data was collected using questionnaires and interview guides from 113 participants comprising 86 academic staff, 23 library staff and 4 university librarians. SPSS was used to analyse quantitative data while qualitative data was analyzed thematically. The findings showed that academic staff believed to be digitally literate could not practically use the skills in accessing and utilizing digital information. The study recommends continuous digital literacy training for both academic staff and library staff.
Emerging Technology and New Vistas in Library and Information Science: Padma Shri Prof. P. N. Kaula Centenary Volume. Eds. Prof C. R. Karisiddappa, Dr P. K. Gupta and Prof. N. Laxman Rao. Managing Editor Dr. S. P. Sood. 2024, Raj Publishing House, Jaipur. Pages. xii, 278, 22cms. ISBN: 978-93-88997-68-3. Price Rs. 699/-
Authors: Asundi A. Y.
Published: July 2024

No Abstract.
Mapping Doctoral Research in Library and Information Science in India, 1950-2023. 2V. Vol. 1: Inventory of Doctoral Dissertations. Vol. 2: Appendices and Indices to Inventory of Doctoral Dissertations. Singh, Shashi Prabha and Babbar, Parveen. Synergy Books India: New Delhi, 2024
Authors: Sharma Jaideep
Published: July 2024

No Abstract.
Opportunities to Improve Health Economic Outcomes in Coronary Artery Disease: A Review of Care Pathways in the United States Healthcare System
Authors: Haberkorn Sebastian , Hummel Marjan , Greef Bianca , Franke Jennifer , Pesigan Ramon , Vyas Pearl , Kulkarni Aparna
Published: July 2024

Background: Despite medical advances, coronary artery disease remains the leading cause of death worldwide. Evidence suggests that current uptake and efficacy of strategies in coronary care are suboptimal. This review aimed to investigate key areas for improvements in coronary care in the United States, and to estimate the potential health gains if existing strategies were improved. Methods: A targeted literature review of the acute and chronic coronary artery disease care pathways was conducted to identify areas where health outcomes could be improved in the United States if uptake or efficacy of existing strategies were optimal. Using hypothetical scenarios of maximally improved efficacy or uptake from published literature and health impact modeling, we calculated potential additional lives saved and potential reductions in direct medical costs, using Medicare rates as proxy, if improvements were realized. Results: We identified the following areas where improvements in uptake or efficacy of existing strategies could positively impact coronary artery disease outcomes in the United States: primary prevention, early detection, efficient diagnosis, reducing time to reperfusion, and secondary prevention. Improvements in primary and secondary coronary artery disease prevention have the potential to reduce annual direct medical costs by approximately $17 billion USD and $5 billion USD, respectively. Further, if the efficacy of existing preventive strategies was improved to 80%, then 102,000 (primary prevention) and 32,000 (secondary prevention) lives could be saved annually. Improvements in early detection, more efficient diagnosis, and reducing time to reperfusion could also substantially increase lives saved by increasing the uptake and efficacy of timelier percutaneous interventions, and potentially reduce annual direct medical costs by $1 billion USD. Conclusions: Improvements in primary prevention offer the greatest potential for lives saved and medical costs avoided. Future innovations should focus on advancing existing primary preventive strategies, while simultaneously driving innovation towards developing effective novel strategies in each of the key areas for improvement.
An Innovative Prone-Position Head Support for Spine Surgery: An Alternative Aimed at Mitigating Risks while Maintaining Good Exposure and Facilitating Effective Anesthesiological Interventions - A Technical Note
Authors: Rocha Guilherme , Junior Aluízio , Cardoso Maurício , Ribeiro Diogo
Published: July 2024

This article aims to describe the development of a head support for prone spinal surgery, which allows the patient's head to be positioned in neutral alignment with the body and enables monitoring of the position of the eyes, mouth, nose, and orotracheal tube, thus avoiding damage due to poor positioning during surgery. A literature review was conducted focusing on complications resulting from head positioning in different supports to develop an option that would reduce the risks of injury. It was developed a support that protects the patient's head and allows easy visualization of the face during surgery, with sufficient space for the anesthesia team to manage the orotracheal tube if necessary. Since its creation, no serious complications have been observed in the use of this support.
Blindness Due to Severe Influenza B Infection: Case Report
Authors: Badía Federica , Alonso Emilia , Pujadas Mónica , Filardi Albertina , Goldara Joaquina , Pirez María
Published: July 2024

Introduction: Influenza is an acute febrile infectious disease with respiratory manifestations, in a variable degree of severity, and a seasonal epidemic distribution. In healthy children, it usually presents as mild and self-limiting, but it can evolve into severe forms with significant morbidity and mortality. These include neurological manifestations such as influenza-associated encephalopathy and acute necrotizing encephalopathy. Objective: To report case of a previously healthy child who developed severe pneumonia due to influenza B and subsequent blindness associated with ANE. Case Report: previously healthy, five years old male, not vaccinated for seasonal influenza, was admitted with four days of fever and respiratory symptoms. Initial evaluation reveled respiratory impair and he was admitted to the critical care unit for respiratory distress syndrome. Influenza B antigen was detected in upper respiratory swab by immunochromatography. Initial laboratory: White blood count; 20300/L, C- protein reaction: 300mg/L, AST 176 U/L, LDH 2549 U/L. He required 11 days of invasive respiratory support due to severe hypoxemia. When support was withdrawn, severe bilateral visual impairment was observed without other neurological manifestations. Magnetic Resonance Image revels bilateral temporo-occipital cortico-subcortical lesions and in both cerebellar hemispheres, with a lacunar image in the left thalamus; no involvement of the optic nerve was observed. Close watching was workup without pharmacologic intervention. He starts recovering vision 5 month later. Discussion: influenza-associated encephalopathy and acute necrotizing encephalopathy are recognized as rare inflammatory complications associated with influenza and other virus infections. Cases of blindness associated with necrotizing encephalopathy are reported. Treatment with corticosteroids, intravenous immunoglobulin, hypothermia, and plasmapheresis are propose; roll of oseltamivir remain unknown. Tocilizumab represents a potentially rational approach to ANE management. Conclusion: Influenza infection could be severe, including neurological complication. Vaccination is the only primary prevention tool.
Prevalence of High Blood Pressure, Risks Factors, and Knowledge Deficit in Apparently Healthy College Students
Authors: Kessler Theresa , Rayman Lynette
Published: July 2024

Background: College students are assumed to be generally healthy, thus, elevated blood pressure can be easily missed in this population. However, recent research on college students has demonstrated increasing rates of elevated blood pressure. Situations that increase risk of elevated BP include higher levels of stress related to college education as well as other common stress producing events in life. Additionally, college students may engage in behaviors that increase risk such as eating poor diets, drinking alcohol, and not exercising regularly. The purpose of this study was to assess the prevalence of elevated blood pressure and risk factors in undergraduate college students and develop a campus wide educational initiative. Methods: Undergraduate students at a faith-based, Midwestern university (n = 138) participated in a cross-sectional study. Demographic data, standardized BP measurements, risk factors, and perceived stress levels were collected via a Google form and in-person assessments. Results: Fifty-two percent of college students had an elevated systolic blood pressure, and 30% had elevated diastolic blood pressure. Male students had significantly higher systolic (X2 = 101.343, p = .005) and diastolic blood pressure readings (X2 = 144.44, p < .001) compared to female students. There was no association between year in school and stress levels (X2 = 315.83, p = .102). Stress and systolic blood pressure were not correlated (r = .121, p = .180) nor were stress and diastolic blood pressure (r = .075, p = .408). Following the educational initiative, 96% of students (n = 91) were able to accurately define elevated blood pressure, risk factors for hypertension, and strategies to lower blood pressure. Conclusions: It is vital that blood pressure assessments become a priority for college students. These assessments must be followed by interventions aimed at reducing blood pressure levels, stress, and risk factors related to hypertension to prevent the long-term effects of cardiovascular disease. Healthcare providers on college campuses, including and perhaps most effectively students in health-related fields, should be involved in working with this population to increase awareness and screening efforts.
Metadichol®-induced expression of circadian clock transcription factors in human fibroblasts
Authors: Raghavan P.R.
Published: July 2024

Circadian clock genes regulate many physiological processes, including sleep, metabolism, inflammation, and cancer. Disruptions in these cycles are associated with heightened vulnerability to cancer, psychiatric diseases, and neurological problems. Circadian clock genes play a vital role in the growth and progression of cancer. Manipulating the circadian clock mechanism can eliminate cancer cells, augment the effectiveness of chemotherapy, eliminate senescent cells, and reinstate regular circadian cycles. The circadian clock genes that are crucial for regulating the daily physiological processes of mammals include Cry1, Bmal1, Per1, Ppargc1a, and Clock. Currently, there is a lack of information regarding small molecules that can effectively control and activate all five transcription factors. By subjecting fibroblasts to treatment with Metadichol, we can induce the expression of all the genes, as evidenced by the results obtained from quantitative real-time polymerase chain reaction (qRT‒PCR). The administration of metadichol significantly enhanced the expression of the Cry1, Clock, and Ppargc1a genes in human fibroblasts, resulting in a four- to fivefold increase in expression. Metadichol successfully maintained the expression of the Per1 and Bmal1 genes at a dose of 100 ng. Clock and Bmal1 heterodimers initiate the activation of Cry1, Per1, and other clock genes via a feedback loop. The Cry1 and Per1 proteins inhibit the function of Clock-Bmal1. Ppargc1a regulates the expression of Clock and metabolic genes. Metadichol did not result in elevated levels of Per1 and Bmal1 expression, suggesting that it does not directly affect these genes. Metadichol is a nontoxic molecule, and its effects on circadian rhythm can have significant implications for human health to alleviate the progression of numerous ailments and diseases
Changing Trends of Tubercular Assault on Reproduction
Authors: Chatterjee Siddhartha , Bagchi Bishista , Datta Abira
Published: July 2024

Background and Objectives. Genital tuberculosis (GTB) is a rare disease in developed countries but is an important cause of subclinical chronic pelvic inflammatory state and infertility in 1–18% of women, being as high as 18 % in India. What we are observing nowadays GTB is changing its way of assault to reproductive process less by infection but more by infestation of the genital tract and thereby leading to harmful molecular changes or may be immunomodulation locally. Reduction of infection may be due to increased surveillance, treatment or use of antibiotics for other reasons indiscriminately, which may make the bacteria dormant. It is being observed as a silent invader of the genital tract of both the female and male partners. It is to be kept in mind that mycobacteria, non- pathogenic to humans, may also cause molecular assault on reproduction. At present, our cohort of patients can be categorized in three groups a) Frank tuberculosis b) LGTB infection c) LGTB infestation There has been extensive research about the involvement of genital tuberculosis in female infertility. Various studies have been undertaken to screen and detect latent genital tuberculosis in apparently normal infertile couples intervening fertility at molecular level. The adverse effects of latent genital tuberculosis, as found in current researches, on the female and male reproductive process has been addressed in the current review. Methods Endometrial aspirates at mid-luteal phase and samples of menstrual blood were collected aseptically from each of those women enrolled in this study and stored at - 80°C for DNA-PCR (Polymerase chain reaction test) and cytokine study. Multiplex polymerase chain reaction (PCR) were performed. DNA-PCR test and sperm DNA fragmentation tests were carried out in semen samples, collected according to WHO guidelines, from male partners in question. Observation. It is being observed that pro-inflammatory cytokines showed significantly different values in TB-PCR- positive and TB-PCR-negative groups. Sperm DNA fragmentation index also appears to be quite high in TB- PCR positive males.Conclusion. LGTB infestation has been found to be responsible for unfavourable molecular changes in reproductive tract and thereby causing a negative impact on fertility. Keywords: latent genital tuberculosis, infertility, cytokine, tubercular infestation, tuberculosis- polymerase chain reaction,
Fighting for Better Representation of Women in and on RTÉ: Women’s Work in Promoting Gender Equality at Ireland’s National Broadcaster, 1979-1981
Authors: Arnold Sarah
Published: July 2024

This article examines the role that women’s activism and advocacy played in early Irish television and the opportunities for and representation of women in national broadcaster Radio Telefís Éireann (RTÉ). It focuses on two groups: RTÉ’s own Working Group on Women in Broadcasting, which reported in 1981, and the Women in Broadcasting Study Group of 1980, headed by Senator Gemma Hussey. Both investigated practices of employment of women and the roles that they undertook as well as the role of women in RTÉ programs and in television advertising on RTÉ. The article argues that, although there were tensions between the two groups and each group had different interests, different methodological approaches in their reports and were received in the public and by RTÉ very differently, they effectively worked together to compel RTÉ to implement their recommendations and take the issue of gender equality more seriously on a long-term basis.
Influence of Russian and Nato Rivalry on Ukrainian National Security during Volodymyr Zelensky's Presidential Term
Authors: Rimapradesi Yulia , Taslim Naqia Salsabila , Putra Riza
Published: July 2024

Since before the Cold War and until the fall of the Soviet Union, there have been tense relationsbetween Russia and NATO. Russia, which succeeded the Soviet Union as its heir, inherited a fewprivileges due to its downfall. Russia grew to be the most prominent, prosperous, and richest nationamong the CIS nations, having a significant political impact on Eastern and Central Europe. AsNATO, a security agreement, increases its influence, Russia feels threatened and does not want tocease to exist. The rivalry between the two actors affects neighboring Russia, including Ukraine.Zelensky's decision to speed up the integration process of the NATO security pact provoked Russianoutrage because it was articulated as a challenge, and practically, the actions taken by Zelensky couldnot accelerate his membership in NATO. Russia launched a military invasion of Ukraine that hadimplications for the neighboring country's national security crisis. In analyzing this thesis, the authorsused the concept of rivalry to analyze the relationship between Russia and NATO and the idea ofnational security to analyze the status quo of Ukraine due to Russian-NATO influence. The researchmethod was descriptive, using data from books, journals, and several other references. This studyfound a Ukrainian national security crisis in the Zelensky era due to the influence of Russian andNATO rivalries.
Role of UN Women in Addressing Women's Rights in Afghanistan under Taliban
Authors: Azizah Nur , Ahsana Fahriyya Noor
Published: July 2024

The current condition of Afghanistan under the Taliban government creates considerable humanitarian problems, especially concerning the rights of women and girls. The Taliban threatens Afghan women by implementing several detrimental policies prohibiting them from going to school, working, and leaving the house. The Taliban restricted the movement of women workers and created an insecure space. This research aims to explain the role of UN Women in responding to humanitarian issues in Afghanistan, especially those related to women. This study used a descriptive method with literature sources such as books, journals, notes, and related reports. The findings indicated that UN Women is committed to assisting Afghan women in restoring their rights under Taliban rule. UN Women, as an International Organization, plays a role as an arena for Afghan women by facilitating women to speak, one of which is in a series of events at the UN Security Council Open Debate on Women, Peace, and Security, which was held at the UN Headquarters in New York. UN Women also works as a donor by providing financial assistance, which will be allocated to the needs of Afghan women. In addition, UN Women acts as an advocate through various activities.
Conflict-Induced Displacement and Food Insecurity: The Case Of Burkina Faso As Sahel’s Growing Epicenter of Conflict
Authors: Prisca Lusiani Putu , Nisadina Yodana
Published: July 2024

This article discusses how the military conflict in Burkina Faso affects food insecurity and the welfare of its people. This issue poses a threat to its citizens' ability to achieve human security, which focuses on welfare and basic human rights, including the availability and access to adequate food. This article is qualitative research, and the analysis of this phenomenon comes from reference articles, books, news, reports, and official documents. The theoretical approach used is related to Conflict-Induced Displacement, Human Security, and the four main dimensions of Food Security, namely food availability, access, utilization, stability, and displacement of communities due to conflict. The results of the analysis show that the geographic location of the country of Burkina Faso, which is confined between the West African mainland, makes it vulnerable to military conflict affiliated with Jamaat Nusrat al-Islam wal-Muslimin (JNIM) and is now the center of conflict in the Sahel region. The author also found out that the main reason for ongoing hunger and malnutrition in Burkina Faso is because its people were forced to be displaced due to armed conflict in the region.
Media Coverage of Sexual Violence Cases in the Russia-Ukraine War
Authors: Sallimi Hadidah , Jatmika Sidik
Published: July 2024

The purpose of this research is to examine how international news sources have narrated the sexual violence issues during the recent Russia-Ukrainian conflict. This research used the Narrative Policy Framework to analyze not only the function of news narratives but also the elements (such as characters) portrayed in rape cases (criminals, heroes, and victims). Furthermore, NVivo Pro was used to process the research data qualitatively. According to the findings, international news sources like The Guardian, CNN, and Al Jazeera have largely reported on the claim that sexual violence, especially rape, has been used as a 'weapon' by the Russian military in its attacks on Ukraine. Ukrainian women, men, children, girls, and boys make up the vast majority of the victims here. Meanwhile, the Russian government and army are presented as villains in the narrative. Different narratives emerge when the three media outlets discuss actors in terms of heroic roles, as shown by this research. There are signs that the media has its objectives, particularly in the context of the Ukraine-Russia war, based on the disparities between the narratives given to the hero characters by the media.
Seamless collaboration: The integral role of anaesthesiologists and orthopedicians in patient care
Authors: Shetti Akshaya N
Published: July 2024

In the dynamic field of orthopedic surgery, the collaboration between anaesthesiologists and orthopedicians is paramount to ensuring optimal patient outcomes. By examining the synergistic relationship between these two specialties, we explore how coordinated perioperative care, from preoperative assessments to postoperative management, can significantly improve clinical results. Anaesthesiologists contribute their expertise in pain management, patient stabilization, and monitoring during surgery, while orthopedicians provide their specialized skills in musculoskeletal procedures. The interplay between these professionals allows for precise surgical interventions and the management of complex cases, particularly in patients with comorbidities. Furthermore, this collaboration extends beyond the operating room, encompassing preoperative planning and postoperative rehabilitation, which are crucial for comprehensive patient care.
A comparative study of functional outcome of percutaneous kirschner wire fixation versus philos plating of proximal humerus fractures
Authors: Bhosale Akshay , Agrawal Mayur , Pimpale Tushar
Published: July 2024

: Proximal humerus fractures, accounting for approximately 5% of all fractures, pose a significant challenge in orthopedic management due to their complex anatomy and diverse fracture patterns. Treatment options range from conservative methods to various surgical interventions, each with its pros and cons. This study specifically compares two commonly employed surgical techniques: Open reduction & internal fixation with PHILOS plate and percutaneous k-wire fixation with/without external clamps. This study aims to address the effectiveness of each technique by evaluating functional outcomes using validated scoring systems like the Constant-Murley Score.

To assess the functional outcomes of two surgical treatment methods (K-wire application and PHILOS plate fixation) for proximal humerus fractures.

: A randomized prospective study was conducted on patients coming to the Orthopaedics outpatient department or casualty of tertiary care hospital for a duration of 1 year from Dec 2022 to Nov 2023. A total of 18 patients were included in the study.

The mean Constant- Murley Score (CMS) was 81 +/- 6.13 for the PHILOS plating group and 76.88 +/- 7.37 for the K-wire treated group with a p-value of 0.08. The results for CMS were excellent in 22.2% of patients and good in 66.7% of patients in PHILOS treated group and excellent for 11.11%, good for 66.67% and satisfactory for 22.2% in the K-wire treated group.

Both groups achieved satisfactory functional outcomes with CM Score at the final follow-up. Both techniques achieved favorable outcomes, with a majority of patients in both groups (88.89% for PHILOS and 77.78% for K-wire) achieving good to excellent results based on the CMS scores.
Identities in Flux: An Interview with Jess Chanliau on August 21, 2020
Authors: Joubin Alexa Alice , Chanliau Jess
Published: July 2024

This interview with non-binary actor Jess Chanliau, conducted by Alexa Alice Joubin, explores genderplay onstage. A bilingual actor, Chanliau spoke candidly on their experience of either being tokenized or being cast frequently as cisgender women. Despite being asked disproportionately to perform the emotional labor of speaking on behalf of trans communities, Chanliau has created meaningful dialogues with industry professionals to address equity issues regarding gender, race, and disability. They reflect on the duality of being marginalized while enjoying certain privilege and offer suggestions on how to hold ourselves accountable and help to dismantle transphobic practices in the entertainment industry.
Nonlinear dynamics of solid-state microwave devices
Authors: Usanov Dmitrij ,   Saratov State University
Published: July 2024

Investigation results of nonlinear dynamics of various kind of semiconductor devices in the microwave circuits are summarized. The possibility of qualitative variation of VA-characteristic form of semiconductor devices on exposure to microwave radiation is noted. The difficulties of theoretical description of experimentally observed sequence of operation regime variation of semiconductor microwave devices with power increase of influenced microwave signal are emphasized.
Influence of thermal velocity distribution on electron beam - backward electromagnetic wave interaction
Authors: Bessudnova Nadezhda ,   Saratov State University, Rozhnev Andrej , Trubetskov Dmitriy ,   Saratov Branch of Kotel`nikov Institute of Radiophysics and Electronics of Russian Academy of Sciences,   Saratov State University
Published: July 2024

One—dimensional linear theory of interaction between electron beam and backward electromagnetic wave in transmission line is presented taking into account arbitrary velocity distribution of electrons and allowing correct consideration of finite length of interaction region. Influence of electron velocity spread оn start oscillation regime of low— voltage backward—wave oscillator is analysed. Calculations are carried out for rectangular, Lorentz and Maxwell distributions.
Professor V.D. Zernov letters of the period of foundation and development of Saratov University 1909-1914
Authors: Solomonov Vladimir ,   Saratov State University
Published: July 2024

In the article the basic life stages of V.D. Zernov, Doctor of Physics and Mathematics, one of the first professors of Saratov University, opened in 1909, are briefly covered. The article completes the first publication of V.D. Zernov letters, concerning the events of the period of Saratov University foundation. The introductory article, comments and preparation of the texts for publication are made by V.A. Solomonov.