bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Analysis of Minimally Invasive Single-segment Reduction and Internal Fixation in Patients with Thoracolumbar Fractures
Authors: Chen Sun Xiu
Published: July 2021

Objective: To study the clinical effect of minimally invasive single-segment reduction and internal fixation in patients withÂ thoracolumbar fractures. Methods: From June 2013 to June 2014,Â 100 patients with thoracolumbar fractures were selected as theÂ subjects and they were randomly divided into observation groupÂ (50 cases) and control group (50 cases). The patients in theÂ observation group were treated with minimally invasive single-segment reduction and internal fixation. The patients in the controlÂ group were treated with short segmental fixation. The clinical effects of the two groups were compared. Results: There was noÂ significant difference in the compression rate and Cobb angleÂ between the two groups before and after operation (P> 0.05). ForÂ all patients who were followed up for the last time, the Cobb angleÂ was significantly lower in the observation group than in the controlÂ group (P <0.05). The social function, affective function andÂ physical pain score of the observation group were significantlyÂ better than the control group (P <0.05). The amount of bleeding inÂ the observation group was (250.4 Â± 41.0) ml, which wasÂ significantly lower than that in the control group (267.5 Â± 32.8) ml.Â The time required for the operation was (90.2 Â± 35.4) min, whichÂ was significantly lower than that of the control group (104.5 Â± 22.6)Â min (P <0.05). After treatment, the prognosis was 70.00% and theÂ excellent and good rate was 98.00%, which was significantly higherÂ than that of the control group (46.00%) and 78.00% (P <0.05).Â Conclusion: Thoracolumbar fractures in patients with dilated channel minimally invasive single-segment reduction and internalÂ fixation treatment can effectively repair the patient's vertebralÂ height and Cobb angle and the degree of correction after surgeryÂ was significantly better, safer and worthy of clinical recommendedÂ use.
Common Nursing Safety Problems and Nursing Management Strategies of Tumor Inpatients
Authors: Nan Sang
Published: July 2021

Objective: This study aims to analyze the relatively commonÂ problems of nursing safety of tumor inpatients and to study theÂ effect of implementing nursing safety management. Methods:Â The data of reference group are selected from patients admittedÂ to hospital before the nursing safety management were fully implemented in the hospital from March 2015 to September 2015.Â The experimental group data are selected from patients admittedÂ to hospital after the nursing safety management were fully implemented in the hospital from October 2015 to March 2016. TheÂ total number of nursing adverse events, the total rate of nursingÂ disputes and the total satisfaction rate of nursing management ofÂ two group of tumor inpatients were calculated. Results: The totalÂ nursing adverse events of tumor inpatients in the experimentalÂ group were significantly different with the calculated values ofÂ the tumor inpatients in the reference group (p<0.05 data comparative statistics). Similarly, the satisfactory total rate of nursing management for tumor inpatients in experimental group wereÂ also significantly different with the calculated value of the tumorÂ inpatients in the reference group (p<0.05 data comparative statistics). Conclusion: The findings suggest that nursing safetyÂ management to tumor inpatients should be highlighted as suchÂ program maybe useful to address the nursing safety problems inÂ the hospitalized patients with tumor.
Study on the Clinical Application of Pain Treatment Efficacy Evaluation and the Nursing of Patients with Chronic Non-cancer Pain
Authors: Han Qian
Published: July 2021

Objective: To evaluate the pain degree of the patients withÂ chronic non-cancer pain by using the evaluation model constituted by heart rate variability, anxiety and depression scale andÂ quality of life rating scale. This study also aims toevaluate theÂ efficacy after treatment and nursing intervention. Methods: 100Â patients with chronic non-cancer pain treated in the hospital from February 2016 to April 2017 were selected to compare their heartÂ rate variability, score of anxiety and depression, score of qualityÂ of life and NRS score before and after treatment and nursing intervention. Results: After treatment and nursing intervention, the heart rate variability time domain SDNN significantly increasedÂ (P ï¼œ 0.05). The score of anxiety and depression was lower thanÂ that before intervention (P ï¼œ 0.05) while the scores of variousÂ dimensions of quality of life were higher than those before intervention (P ï¼œ 0.05). The results also showed that NRS score wasÂ lower than that before intervention (P ï¼œ 0.05). Conclusion:Â These findings suggest that the measurement combination ofÂ heart rate variability, anxiety and depression scale and quality ofÂ life rating scale can be used as an evaluation model to evaluateÂ the pain degree of the patients with chronic non-cancer pain theÂ efficacy after treatment and nursing intervention, which is worthy of clinic application.
An Overview Study of Health Insurance in India
Authors: Vandali Vijayaraddi
Published: July 2021

Health insurance is a mechanism by which a person protects himself from financial loss caused due to accident and/or disability.Â The chairman of Insurance Regulatory and Development Authority (IRDA) has mentioned that low consumer awareness and insufficient healthcare infrastructure are the major hindrances toÂ widen the reach of healthcare insurance in India. Healthcare costsÂ have witnessed a phenomenal rise in the current times. This hasÂ led the customers to insure not only themselves but their familyÂ members for any future medical expenses and other related requirements. The need to insure assumes is more importance forÂ older generations who are either retired or will be retired in nearÂ future. Given high health cost, it is important for us to get covered for health risks. With this, a good insurance policy is neededÂ to cover doctor's visit, laboratory tests, hospital stays and diagnostic tests. There are quite a few companies covering healthÂ risks with good insurance policies. Health insurance (popularlyÂ known as Mediclaim) offers protection in case of unexpected medical emergencies. In case of a sudden illness or accident, theÂ health insurance policy takes care of the hospitalization, medicalÂ and other costs incurred. Thus, health insurance to be introducedÂ to all consumers in India to protect them from financial lossÂ caused by unfortunate incidents.
Analysis of the clinical value of Baogan Lishui decoction and convetional western medicine in treating Hepatitis B cirrhosis refractory ascites
Authors: Lin Huaide
Published: July 2021

Objective: To investigate the clinical effect of combination treatment of Chinese medicine Baogan Lishui decoction and western medicine on hepatitis B cirrhosis related refactory ascites.Method: Control group was given conventional western medicine therapy while the observation group was given same conventional western medicine therapy with additional of Chinese medicine Baogan Lishui decoction.Result: The total effective of clinical treatment on hepatitis B cirrhosis related refractory ascites in observation group was higher than that of the control group which was 88.89% compared to 71.11%, respectively and it was significant different (p<0.05).Conclusion: The combination treatment of Chinese medicine Baogao Lishui decoction and conventional western medicine can significantly increased the treatment effect on hepatitis B cirrhosis refractory ascites, and thus increases the quality and safety of life.
Investigation and Analysis of Rational Drug Use of Residents in Changshou District of Chongqing, China
Authors: Yu Jiangxia , Fan Yongtong , Wu Ruizhu , Ji Huanhuan
Published: July 2021

Objective: To acquire information about residents of Changshou District's knowledge levels and their behaviors of drug use, so that implementation strategies of rational drug use can be formulated accordingly to promote and spread health education of rational drug use.Â  Methods:Â  Online and offline surveys were randomly conducted about rational drug use conditions of residents in Changshou District by questionnaires. Online questionnaires were sent to residents of Changshou District by Wenjuanxing, an professional platform used for surveys. Offline questionnaires were mainly distributed to residents of communities in Changshou District. All the online and offline statistics were analyzed and counted. Results: Three hundred and nine (309) questionnaires were distributed (176 online questionnaires and 133 paper questionnaires), and the effective recovery rate was 75.4%. According to investigation and survey, conditions of residentâ€™s rational drug use were optimistic. Only 8.15% residents who participated in the survey (or research subjects) took paracetamol tablets and vitamin C Yinqiao tablets (also known as VC Honeysuckle Pills) at the same time when they had a cold or fever. Among 8.15% residents, 5.15% frequently took paracetamol, caffeine and aspirin powder (also known as headache powder); 80.26%, checked expiration date of drugs before taking medicine; more than 50%, knew that drinking after taking medicines such as cephalosporin is prohibited. Common irrational problems caused by drug use were as follows: 40% research subjects took dietary supplements as drugs, and 28% of them failed to know the correct usage and dosage of drugs. Proportion of drugs that were taken with irrational usage and dosage were antibiotics (64%), antibacterial (52%), drugs for patients with diabetes mellitus (36%), drugs for patients with hyperlipidemia , hypertension and hyperglycemia (32%), vitamins (24%), drugs for treatment of common cold and cough(20%) and others. Conclusion: Publicity of rational drug use should not be restricted to specific population, and knowledge of safe drug use is supposed to be actively popularized. Contents of rational drug use are as follows: Guide the public to correctly understand the functions of vitamins and dietary supplements strengthen publicity of rational use of drugs such as antibiotics, antibacterial drugs, drugs for chronic diseases, cold and cough, etc. Focus should be given on usage and dosage of drugs, use of antibacterial drugs, and repeated and excessive use of drugs caused by joint use of drugs with same ingredients of OTC drugs for treatment of common cold and cough.
Investigation of Occupational Hazards in Transport Wharf of Liquid Chemicals
Authors: Jiang Yizhou , Zhang Dongxu , Weng Datao , Chen Xuli
Published: July 2021

Abstract: Occupational health management of liquid chemical transport wharf is still in its infancy, in order to grasp the occupational health status of employees in the industry and improve the occupational health management level of employees, taking the liquid chemical transport wharf of an enterprise as the investigation object, according to the relevant domestic occupations. Hygiene standards, using the combination of on-site occupational hygiene survey and workplace occupational hazard factors detection, identify the occupational hazard factors of the wharf, and detect the degree of hazard. The survey results show that the overall occupational health of the wharf is basically good, but the noise index is slightly exceeded. It is suggested to further improve the occupational health management level of the wharf by improving the protection technology and strengthening the administrative management.
Integrated Chinese and Western Medicine for the Treatment of Acne Associated Blepharokeratoconjunctivitis Case 1
Authors: Gao Mingmei , Liu Chengyun
Published: July 2021

Abstract: This article reported a case of acne associated blepharokeratoconjunctivitis (BKC) in a young woman. During her pregnancy, to reduce the systemic use of drugs due to its side effect, localized eye drop, oral administration of Chinese medicine and fumigation treatment were adopted. In integrated Chinese and Western medicine treatments, localized treatment simultaneously with the intrinsic conditioning of the patientâ€™s physique could treat both the symptoms and root causes of disease. It can effectively improve clinical efficacy, shorten the course of the disease and reduce patient suffering and recurrence.Â
Analysis of Combined Therapy and Treatment Effect of Localized Ultraviolet Irradiation and Shengji Yuhong Cream on Diabetic Foot
Authors: Zhang Yiping , Tang Xiaomei , Zhu Min , Wang Jumei
Published: July 2021

Abstract: Objective: To investigate the treatment effect of combined application of localized ultraviolet irradiation and Shengji Yuhong Cream on diabetic foot patients. Methods: Diabetic foot patients in the control group were treated with localized ultraviolet irradiation on the basis of conventional treatment. The study group was added with Shengji Yuhong Cream on top of the localized ultraviolet irradiation on the basis of conventional treatment. Results: The results of ankle brachial index and dorsal foot skin temperature of that two groups before treatment were compared, P>0.05. After treatment, the ankle brachial index and dorsal foot skin temperature of the study group were better than those of the control group. The comparison between the groups and within the group was P<0.05. The total effective rate of the study group (95.65%) was higher than that of the control group (71.11%), P<0.05. Conclusion: The application of localized ultraviolet irradiation and Shengji Yuhong Cream in the treatment of diabetic foot is effective.
Analysis of the Influence of Operating Room Nursing Care Management on the Incidence Rate of Nosocomial Infection in Orthopedic Surgery Patients
Authors: Tan Lili
Published: July 2021

Abstract: Objective: To analysis the influence of operating room nursing care management on the incidence rate of nosocomial infection in orthopedic surgery patients. Methodology: Fifty six orthopedic surgery patients who admitted into the hospital between January to December 2018 were enrolled into this study and randomly divided into two groups, which were the control group (under general management) and the observation group (under the operating room nursing care management). Further, the incidence rate of nosocomial infections, the incidence rate of irregular nursing care phenomena, the satisfaction score of nursing care management, and the quality of life score were observed and recorded. Result: The incidence rate of nosocomial infection, the incidence rate of irregular nursing care management, the satisfaction score of nursing care management, and the quality of life score of the observation group were compared to that of the control group, and the result showed P<0.05, indicates the statistical significance between the data indicators. Conclusion: The use of operating room nursing care management in patients with orthopedic surgery has shown a significant effect.
Perioperative Nursing Care Experience of a Case of Postoperative Recurrent Grade II-I Left Frontal Astrocytoma
Authors: Yin Xiangyi , Zhu Xiaowen , Meng Xianlan , Zhou Lihui
Published: July 2021

Objective: To investigate the effect and value of perioperative nursing intervention on postoperative recurrent grade II-I left frontal astrocytoma. Method: Nursing care procedures: left frontal lobe of the patient was occupied by a large space. Clinical teaching of nursing was strengthened. Preoperative, intraoperative and postoperative care and ward patrol were enhanced. Close attention was paid on consciousness, pupil, vital signs, body temperature, lungs condition, cranial and nerve function of the patient. Extra care was taken in keeping the incision clean and dry. Blood diffusion condition in wound was observed. Active cooperation with doctor was taken to prevent occurrence of pulmonary infection, urinary tract infection, pressure ulcer and other complication. Results: After operation, the patient had stable condition, clear mind and consciousness. There was no occurrence of epilepsy but intracranial hemorrhage. Pneumatosis was relieved. There was no infection and other complication. Conclusion: Application of comprehensive nursing intervention could effectively improve quality of life of patient and reduce incidence of postoperative complication in patients with brain tumor.
Seasonal Changes of Hemorheology in Patients with Intracerebral Hemorrhage in Acute Phase
Authors: Jia Haiyu , Ma Yongbin
Published: July 2021

Objective: To explore the seasonal changes of hemorheology in patients with intracerebral hemorrhage in acute phase. Methods: The hemorheology indexes were detected in 100 acute cerebral hemorrhage patients and 30 normal persons. The observed group were divided into summer group, transition season group and winter group according to traditional solar terms, then the hemorheology indexes of different groups were compared. Results: Compared with control group, the whole blood viscosity increased with statistical significance(P<0.05). The whole blood viscosity of four cut blood rates and plasma viscosity were further compared in summer group, transition season group and winter group, and the indexes were the highest in winter group. Compared with transition season group, the erythrocyte aggregation index and erythrocyte transformation index acute intracerebral hemorrhage patients were decreased in winter group and summer group. The whole blood viscosity, plasma viscosity and erythrocyte sedimentation rate(ESR) compared in each group were increased with statistical significance. There were no significant statistical differences in hematocrit(HCT)  among each groups(P>0.05). Conclusion: The hemorheology indexes in acute intracerebral hemorrhage patients are influenced by changes of different seasons and The blood of acute cerebral hemorrhage patients shows a concentrated tendency. The whole blood viscosity and plasma viscosity of acute cerebral hemorrhage patients were increased more obviously in winter group, which may be a pathophysiological basis of high incidence of acute cerebral hemorrhage in cold season and increase of severe cases.
Evaluation of the Effect of Shenmai Injection on Chemotherapy Efficacy and Side Effects of Acute Leukemia
Authors: Qiao Jianling , Kan Xuan , Qin Fei
Published: July 2021

Objective: To study the effect of Shenmai injection on the efficacy and side effects of chemotherapy in acute leukemia. Methods: Sixty-two patients with acute leukemia admitted to the hospital between February 2018 and June 2019 were enrolled in this study. All patients were divided into observation and control groups according to different treatment methods in chemotherapy. The control group was treated with chemotherapy alone. The observation group was treated Shenmai injection combined with chemotherapy. The treatment effect of the two groups was compared, and the incidence of bone marrow blood and side effects before and after treatment were compared. Results: The therapeutic effect of the observation group was 93.55% which was much higher than that of the control group of 74.19%, P<0.05. The bone marrow blood levels of WBC, PLT and Hb in the observation group before and after treatment were 23.97±3.05, 6.76±1.27, 69.01±8.15, 66.96±9.46, 91.07±8.15, 89.35±7.46, respectively, compared with the control group. The difference in the situation after treatment was found to be significant. The incidence of toxic side effects such as nausea and vomiting, impaired liver function and renal dysfunction in the observation group was 9.68%, which was lower than that of the control group (32.26%, P<0.05). Conclusion: Shemai injection has significant effects on the efficacy and side effects of chemotherapy in acute leukemia and effectively improves the effect of chemotherapy.
A Pragmatic Study on Non-aggressive Doctor-patient Conflict Talk - From the Ecolinguistic Perspective
Authors: Hu Yupeng , Song Jinge
Published: July 2021

Doctor–patient relationship is a very important relationship between doctor and patient and patient’s family member. In interpersonal communication, non-aggressive discourse often leads to conflicting response. It is the most common doctor–patient relationship between doctor and patient. There are limited studies on non-aggressive conflicting response. Language used is the most important basis in conflicting response to non-aggressive discourse. Language and culture are broad and diverse. Different speech methods and language content lead to different response. Based on this, this paper explains response to non-aggressive conflict talkbetween doctor and patient in the perspective of ecolinguistics, to provide reference.
Effects of China-Germany Follow Up Systems on Ventilator Therapy in Patients with Obstructive Sleep Apnea Syndrome
Authors: Chen Yujie , Yang Linglin , Li Yong , He Qinze , Wang Yi
Published: July 2021

Objective: To investigate the effects of different follow-up systems in China and Germany on ventilator therapy in patients with obstructive sleep apnea syndrome. Method: From March 2013 to October 2015, three hundred patients with moderate to severe obstructive sleep apnea syndrome and those who are suitable for ventilator treatment were followed up according to the follow-up system of both China and Germany. The follow-up was carried out for one year to compare the rate of loss to follow-up, ventilator therapy compliance, treatment effect, ventilator side effects and others in the two groups of patients. Statistical analysis was performed using x2 test, P<0.05 for the difference was statistically significant. Results: The rate of loss to follow-up in the German group was lower than that in the Chinese group. The compliance of the German group with respiratory therapy was lower than that of the Chinese group. The side effects of ventilator treatment were lower than those in the Chinese group (P<0.05). Conclusion: The German follow-up system is more effective than the Chinese follow-up system in improving the compliance and effectiveness of ventilator therapy in patients with obstructive sleep apnea syndrome.
Expression of MMP-2 and MMP-13 in Bullous Pemphigoid
Authors: Zhang Haixiang , Shi Xiaoxu , Qin Lanying , Zhao Zishen , Fu Guojun , Peng Jun , Ye Wenjing
Published: July 2021

Objective: To investigate the expression and significance of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-13 (MMP-13) in bullous pemphigoid (BP) skin lesions. Methods: Immunohistochemical SP method was used to detect the expression of MMP-2 and MMP-13 in 32 BP skin lesions, and compared with 15 normal skin tissues. Results: The expression of MMP-2 in the case group was significantly increased (38.56 ± 10.06) compared to the normal control group (21.20 ± 5.98); the expression of MMP-13 in the case group was significantly augmented (18.62 ± 5.90) compared to the normal control group (11.47 ± 8.484). The expressions of MMP-2 and MMP-13 in the skin lesions of patients with bullous pemphigoid were statistically different from those of normal people (both P < 0.05). Compared with the expression of MMP-2 and MMP-13 in bullous pemphigoid, the expression of MMP-2 and MMP-13 was moderately correlated (correlation coefficient was 0.523). Conclusion: The expression of MMP-2 and MMP-13 is significantly increased in bullous pemphigoid skin lesions, suggesting that they may play an important role in the pathogenesis of BP. There is a certain correlation between the expression of MMP-2 and MMP-13, suggesting that the high expression of MMP-13 may play a role in the mechanism that further leads to the high expression of MMP-2.
Effects of 5-hydroxytryptamine Receptor on the Reaction of the Lower Esophageal Sphincter Under the Electrical Field Stimulation
Authors: Li Wei , Li Hefei , Sun Zhenqing , Li Ben , Guo Qiang , Jiang Tao , Liu Xinbo , Feng Yong
Published: July 2021

In the first and second parts of this study, 5-hydroxytryptamine (5HT) receptors, including 5-HT3 and 5-HT4 with the highest expression level, were found in clasp and sling fibres of the lower esophageal sphincter (LES). Specific 5-HT3 and 5-HT4 receptor agonists can induce the contraction effect of clasp and sling fibres of the LES while specific 5-HT7 receptor agonists showed no effects. In the study of this part, the in-vitro muscle tension measurement technology and EFS methods were used to detect the effect of the selective 5-HT receptor antagonist on the clasp and sling fibres of the in-vitro LES under the electrical field stimulation (EFS), and further to ensure the effect of 5-HT receptor in the LES neuroregulatory pathway, and deeply explore the effect of 5-HT receptor in the systolic and diastolic function regulation of the LES.
Application of Standardized Measures in Clinical Teaching of Medical Imaging Department
Authors: Qi Chunhua
Published: July 2021

Objective: To explore the application of standardized measures in clinical teaching of medical imaging department. Methods: Forty-eight medical interns in Department of Medical Imaging of our hospital from February 2018 to May 2019 were selected as research objects. They were divided into 2 groups according to random number table method, with 24 cases in each group. Routine education management was performed in clinical teaching for control group, standardized measure management was performed in clinical teaching for observational group. Performance assessment before and after intervention was compared between two groups of medical students. Results: Before intervention, there was no significant difference in assessment result between two groups of medical students (P>0.05). Assessment result after intervention was higher than before intervention in two groups of medical students. Observational group was higher than control group, the difference was statistically significant (P<0.05). Conclusions: Implementation of standardized measures in clinical teaching of medical imaging department could significantly improve assessment result of medical students, and its application can be considered in clinical teaching.
Timing and Clinical Efficacy of Laparoscopic Cholecystectomy for Acute Cholecystitis at Different Stages
Authors: Zhang Hao
Published: July 2021

Objective: To investigate timing and clinical efficacy of laparoscopic cholecystectomy for acute cholecystitis at different stages. Methods: Clinical data of 100 acute cholecystitis patients admitted to our hospital from March 2018 to March 2019 were retrospectively analyzed. Clinical data of 48 patients who had surgery within 72 hours of symptom onset were classified as group A, and clinical data of 52 patients who had surgery at ? 72 hours of symptom onset were classified as group B. Clinical indicators, rate of conversion to open surgery, and complication were compared between the two groups. Results: Length of hospital stay, operation time, exhaust time and intraoperative blood loss in group A were lower than those in group B, and the differences were statistically significant (P<0.05). Comparison of rate of conversion to open surgery between group A (2.08%, 1/48) and group B (7.69%, 4/52) showed no statistically significant difference (P>0.05). Incidence of postoperative complication was 8.33% (4/48) in group A and 11.54% (6/52) in group B, the difference was not statistically significance (P>0.05). Conclusions: Laparoscopic cholecystectomy within 72 hours of symptom onset has better efficacy than after 72 hours for patients with acute cholecystitis. It could effectively reduce surgical trauma and promote recovery.
Application of Transesophageal Echocardiography in Observing Left Atrial and Left Atrial Appendage Before Radiofrequency Ablation in Patients with AF
Authors: Ma Yiyi , Liu Xiaoming
Published: July 2021

Objective: To report and explain the significance of transesophageal echocardiography(TEE) in the observation of left atrium and left atrial appendage before radiofrequency ablation in patients with AF. Methods: 25 patients with AF were selected as the review objects who received echocardiography in our hospital during June 2018 to June 2019. They had routinely received transthoracic echocardiography (TTE) before preparing for radiofrequency ablation. Then TEE was selected to observe and compare the effect of two detection methods on left atrial and left auricular thrombosis. Results: TEE examinations were given to patients with atrial fibrillation before radiofrequency ablation. Compared with TTE examinations, the detection rate of left atrium and left atrial appendage thrombosis was significantly improved. The two detection methods are different and comparable(P<0.05), which is of great significance in clinical application. Conclusion: The use of TEE has significantly improved the detection rate of left atrial and left atrial appendage thrombosis in patients with AF, and has become an important examination method before the implementation of radiofrequency ablation.
Comparison of the Effect of Combined Cardiovascular Dexmedetomidine and Propofol in Minimally Invasive axillary Odor Surgery with Tumescent Anesthesia
Authors: Xu Chunfei , Gao Xiaoying
Published: July 2021

Objective: The effects of combined dexmedetomidine hydrochloride and propofol in minimally invasive axillary odor surgery with tumescent anesthesia. Methods: A total of 46 patients underwent minimally invasive axillary odor surgery by tumescent anesthesia received in the hospital from May 2017 to January 2019 were divided into observation group (23 cases) and control group (23 cases) according to the random number table method. The control group used propofol, and the observation group underwent minimally invasive axillary odor combined with dexmedetomidine hydrochloride by tumescent anesthesia. The changes of arterial blood pressure (MAP), heart rate (HR) and postoperative complications before and after anesthesia were compared and analyzed between the two groups. Results: After anesthesia, MAP and HR in both groups were lower than before anesthesia, and the observation group was lower than the control group, the difference was statistically significant (P<0.05). Compared with the control group, the postoperative complications were less in the observation group, but the difference was not statistically significant (P>0.05). Conclusion: Compared with the use of propofol, the effect of dexmedetomidine hydrochloride combined with minimally invasive axillary odor surgery by tumescent anesthesia is more obvious, and the postoperative recovery is faster with fewer complications.
Research on the Levels of Serum Vitamin D and IgE and Their Correlations in Infants with Different Allergic Risks
Authors: Feng Lin-lin , Meng Ting-ting , Sun Fengyan , Chen Xiaoyun
Published: July 2021

Objective: To investigate the levels of serum vitamin D and IgE in infants with different allergic risks and to analyze their correlations. Methods: In the present study, the participants were selected and recruited from the infant ward of our hospital from February 2012 to December 2012. A total of 120 patients were selected and recruited. Among these patients, 64 patients with symptoms of allergic diseases were assigned to the experimental group. The remaining 56 patients who had respiratory infections, but without other symptoms of allergic diseases, were assigned to the control group. The serum 25-hydroxyvitamin D3 levels were measured using liquid chromatography tandem mass spectrometry and the IgE levels were measured using radioimmunoassay in both experimental and control groups. Subsequently, the serum 25-hydroxyvitamin D3 levels and IgE levels were compared between the experimental group and control group. Results: The following findings were obtained through data comparison. The serum 25-hydroxyvitamin D3 level in the experimental group was 18.19 ± 7.84 ng/mL, and the IgE level was 551.51 ± 705.88 IU/mL. The serum 25-hydroxyvitamin D3 level in the control group was 21.95 ± 7.834 ng/mL, IgE level was 49.39 ± 32.46 IU/mL. The data comparison indicates that the serum 25-hydroxyvitamin D3 level in the control group was higher than the experimental group, and the IgE level in the control group was lower than the experimental group (P<0.05). Conclusion: The level of vitamin D3 in patients with allergic symptoms is relatively low. This may be one of the causes leading to allergies. At the same time, IgE is also one of the causes contributing to allergies. An elevation of the IgE level is very likely to cause the allergic, and there is a correlation between serum vitamin D and IgE levels. At the same time, research has found that proper supplementation of vitamin D3 can help prevent allergic diseases, and can be considered in a new and high-quality program for the prevention of allergic diseases.
Observation on the Therapeutic Effect of Heat-clearing and Dampness-eliminating Dredging Collaterals Combined with Papaya Antirheumatic Pills on Treatment of Damp-heat Obstructive Ankylosing Spondylitis
Authors: Huang Youling
Published: July 2021

Objective: Therapeutic effect of heat-clearing and dampness-eliminating dredging collaterals combined with papaya antirheumatic pills on treatment of damp-heat obstructive ankylosing spondylitis. Methods: A total of 200 patients with ankylosing spondylitis who were treated in our hospital from January 2018 to October 2019 were selected as the research objects and randomly divided into 2 groups, each with 100 patients. The control group was treated with leflunomide + papaya antirheumatic pills, and the observation group was treated with self-drafted recipe of heat-clearing and dampness-eliminating, the curative effect, visual analogue score (VAS), barthel AS function index (BASFI) score, biochemical indicators and adverse reactions between the two groups were compared. Results: After 12 weeks of treatment, the efficacy of the observation group was higher than that of the control group. The pain score, BASFI score, and biochemical index were lower than those of the control group, and the differences were statistically significant (P<0.05); There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Heat-clearing and dampness-eliminating dredging collaterals combined with papaya antirheumatic pills is effective in the treatment of damp-heat obstructive ankylosing spondylitis, which is beneficial to reduce the degree of pain and inflammation of the affected area, helps patients remain active, and improves activities of daily living.
Research Progress on the Role of Endoplasmic Reticulum Stress in Osteogenic Differentiation
Authors: Jin Nianqiang , Sun Hongchen
Published: July 2021

The endoplasmic reticulum (ER) is the main site for regulating protein synthesis and processing. Endoplasmic reticulum stress plays a role in regulating the osteogenic differentiation of stem cells and general osteoblasts. Bone marrow stromal cells (BMSCs, also known as bone marrow mesenchymal stem cells) are a group of progenitor cells that contain a small number of bone stem cells (SSCs) that rebuild cartilage, bone, stroma, and fat cells that support hematopoiesis and bone marrow. Therefore, due to their self-renewal and differentiation capabilities, they have become an important resource for researching regenerative medicine and tissue engineering treatment strategies. Exposure of osteoblasts to physical and biochemical stimuli facilitates rapid activation of early tissue repair processes in organisms. Therefore, the rational regulation of the induction conditions of osteoblasts has become a hot research topic. This article reviews the recent advances in the role of endoplasmic reticulum stress in the process of osteoblast differentiation.
Application of Multi-team Blood Glucose Management Model in Perioperative Period of General Surgery Patients
Authors: Li Weirong , Zhou Yan , Lu Xiaohua , Liu Yan , Deng Minpin , Wang Xiaolan
Published: July 2021

Objective. In order to explore the application effect of blood glucose management mode of multi-team cooperation in perioperative period of general surgery patients. Methods. The perioperative blood glucose control of 94 patients undergoing surgical treatment in general surgery from January 2016 to March 2019 was reviewed by Non-synchronous. According to the perioperative blood glucose management model of multi-team cooperation, the patients were divided into intervention group and control group. From January 2016 to January 2018, 64 patients who did not implemented the multi-team blood glucose management model were the control group and from February 2018 to March 2019, 30 patients who implemented the multi-team blood glucose management model were the intervention group, compared with two group about the differences in perioperative blood glucose. Results. It is no statistically significant about two group in highest and lowest blood sugar levels under fasting stats; during the fluid diet the blood sugar level of the intervention group was lower than control group(P<0.05),and when the patients was in the semi-fluid or food-feeding period, the highest and lowest blood sugar level is that the intervention group was lower than control group(P<0.05). The time of the blood sugar reaching the standard, the coincidence of complications rate and average hospitalization days in the intervention group were particularly lower than control group(P<0.05). Conclusion. If we adopt multi-team blood glucose management model can better control the perioperative blood glucose of patients undergoing general sugar.
The Value of the Wearable Single-lead Remote Monitoring Device with the Scatterplot in Chronic Disease Management
Authors: Yu Xinyan , Zhang Qinghong , Wang Dong , Feng Yan , Li Fangjie
Published: July 2021

Objective: To study the value of the wearable single-lead remote monitoring device with the scatterplot in chronic disease management. Methods: dmitted into 435 residents accord with the inclusion criteria of 20 primary medical institutions of Yinchuan city, and grouped voluntarily by the implementation schemes were grouped voluntarily according to the implementation schemes. According to one of the three implementation schemes selected, the general practitioner guided the subjects to take on the wearable single-lead remote monitoring device, collecting and uploading the EEG data, then diagnosed and analyzed by the synchronously generated ECG scatterplot, finally, summarized the incidence and the categories, analyzed the differences among these three groups.Results: Among 435 subjects, there were 61 normal patients and 374 arrhythmias with the detection rate of 85.98%; and among the 1672 data collected, there were 606 normal data and 1066 arrhythmia with the detection rate of 63.76%; 880 data in total 333 cases with atrial premature beat; 442 data in total 215 cases with occasional ventricular premature beat; 37 data of 22 cases with frequent atrial beat; 65 data of 28 cases with frequent ventricular premature beat; 13 data of 6 cases with atrial fibrillation; 25 data of 15 cases with excitation conduction disorder; 2 data of 2 cases with atrial flutter; 31 data of 19 cases with ventricular tachycardia; 30 data of 16 cases with conduction block; and 14 data of 8 cases with Para systolic rhythm. comparing the detection rate of arrhythmia in three groups, the difference was not statistically significant (P>0.05). Conclusion: The wearable single-lead remote monitoring device with the scatterplot has high application value in cardiovascular chronic disease management.Its effectively screening, validly diagnosing and detailed classifying are helpful to the early intervention , and the protection of the patients’ lives.
Treatment of Oral Ulcer Based on TCM Syndrome Differentiation
Authors: Yao Ying , Liu Li
Published: July 2021

Oral ulcer is a kind of ulcerative injury that occurs in the oral mucosa and is very common in clinic. In severe case, it can affect the quality of life of the patients. Western medicine treatment of oral ulcer is often prone to relapse, while the effect of traditional Chinese medicine treatment is remarkable.
Effect of Nutritional Diet Therapy in Pediatric Diabetic Patients
Authors: Lu Man , Xu Hongjuan , Pang Xiaolin
Published: July 2021

Objective: To analyze the effect nutritional diet therapy in  pediatric diabetic patients. Methods: The study object was 60 cases of children with diabetes, which were divided into groups and treated separately according to the time of admission, and the treatment effects were compared. Results: After treatment, the glycated hemoglobin level, fasting blood glucose level, blood glucose level at 2 hours after meal, serum calcium level, transferrin level, albumin level, prealbumin level, hemoglobin level, the height, weight, and head circumference of the experimental group were better than those of the control group, and there were significant differences between the groups (P<0.05). Conclusion: The application of nutritional diet therapy in the treatment of pediatric diabetic patients can significantly improve blood glucose levels, nutritional indicators and physical indicators of patients.
A Case Report and Literature Review of Wilson Disease
Authors: Chen Panpan , Zhang Yingying , Qiu Linqing , Yu Xinxin
Published: July 2021

To investigate the clinical characteristics, auxiliary examination and treatment of Wilson’s disease(WD). The clinical data of a child with WD were summarized and analyzed comprehensively in conjunction with the literature reference. WD is a hereditary disease with a large age span, diverse early symptoms, high misdiagnosis rate, abnormal liver function, decreased ceruloplasmin, increased urinary copper, K-F rings, ATP7B gene mutation, ATP7B gene mutations, and abnormalities in abdominal and cranial brain imaging, which can be clearly diagnosed and require lifelong treatment. WD can be diagnosed according to the clinical manifestations and auxiliary examination to reduce misdiagnosis. The timely diagnosis and treatment will improve the prognosis the quality of life.
Clinical Observation of Zhuang Medicine Yangxue Xiaozheng Decoction in Treating the Combined Endometriosis of Dampness and Blood Stasis in Guangxi
Authors: Shi Chuan , Cao Yun , Wang Lei , Wang Xiang , Fang Gang , Bai Rui
Published: July 2021

Objective: To explore the clinical effects of Zhuang Medicine Yangxue Xiaozheng Decoction in treating the combined Ems of dampness and blood stasis in Guangxi; Methods: 100 patients with endometriosis treated in Lili Clinic of Famous Doctor, Guangxi International Zhuang Medicine Hospital from Mach 2016 to May 2017 were chosen as the research object. According to the random grouping method, patients were randomly divided into the treatment group (The Zhuang Medicine Yangxue Xiaozheng Decoction (ZYF) Group) and the control group (Chinese patent medicine SanJieZhenTongJiaoNang (SJZT) group with 50 cases in each group. After treatment, the TCM syndrome score, changes in pelvic mass size, hepatocyte growth factor (HGP) levels, and clinical effects before and after treatment were evaluated. Results: After two courses of treatment, the total effective rate of patients in the ZYF group was 88%, which were significantly better than 70% of the SJZT group. The difference was statistically significant (P <0.05). Conclusion: With a significant effect on patients with the combined Ems of dampness and blood stasis in Guangxi, Zhuang Medicine Yangxue Xiaozheng Decoction can improve the uterine cavity mass and reduce serum HGP level.
Observation of Clinical Treatment Effect of Plastic Surgery of Asymmetric Double Eyelids
Authors: Gao Liang , Xu Shuang , Zhang Miao , Chen Jing , Ma Li
Published: July 2021

Objective: To explore the clinical efficacy of plastic surgery of asymmetric double eyelid. Methods: The clinical data of 70 patients with asymmetrical double eyelid who underwent plastic surgery in our hospital from April 2018 to December 2019 were retrospectively analyzed. The patients were divided into different groups based on different plastic surgery procedures. The control group (n=35 cases) were the patients who underwent double eyelid incision method, and the patients who used embedding double eyelid method were included in the observation group (n=35 cases). The operation time, intraoperative blood loss, incision size, healing time of incision, satisfaction of plastic surgery and occurrence of complications were compared between the two groups. Results: The operation time and incision healing time of the observation group were shorter than those of the control group. The intraoperative blood loss and incision were less than those of the control group, and the satisfaction was higher than that of the control group. The difference was statistically significant (P<0.05). The incidence of complications in the observation group was slightly lower than the control group, but the difference was not statistically significant (P>0.05). Conclusion: For asymmetric double eyelid, it should undergo embedding double eyelid plastic surgery, because the operation time and incision healing time are shorter. And intraoperative blood loss and incision size are smaller, which can improve patient satisfaction and reduce the incidence of complications.
Evaluation of Clinical Application of Chemiluminescence and Real-time, Fluorescence-based Quantitative PCR in Diagnosis of Epstein-Barr Virus Infection
Authors: Geng Huijuan , Wang Yan , Wang Hao , Wang Hao , Sun Jirui , Tang Hui
Published: July 2021

Objective: To compare the effects of clinical application of chemiluminescence and real-time, fluorescence-based quantitative PCR in the detection Epstein-Barr virus (EBV). Methods: The data of chemiluminescence and real-time fluorescent quantitative PCR from 97 patients who were suspected of being infected with EBV from January 2016 to January 2019 in our hospital were analyzed. The specific stage of EBV infection was analyzed, and the differences in results of the two detection methods were compared. Results: Chemiluminescence method was used to detect EBV infection during the active phase. The sensitivity of the chemiluminescence method was 76.7% (56/73) and the real-time quantitative PCR method was 90.4% (66/73). There was a statistical difference between the two detection methods (P<0.05). Conclusion: There was no statistical difference in positive predictive values between the chemiluminescence method and the real-time, fluorescence-based quantitative PCR method in the detection of EBV infection, but the sensitivity of chemiluminescence method is slightly lower than the real-time quantitative PCR method. It is noteworthy that chemiluminescence method is convenient and fast while the real-time, fluorescence-based quantitative PCR method is more accurate, which can provide a more accurate reference for clinical treatment.
A Clinical Analysis of Physical and Neurological Development in very Low Birth Weight Infants with MEIR (Massage, Exercises, Intelligence training, and Rehabilitation training)
Authors: Deng Yonghong , Wang Shulian , Liu Zhaohui , Liao Qi , Zeng Yan
Published: July 2021

Objective: This study aimed to investigate the application of MEIR (Massage, Exercises, Intelligence training, and Rehabilitation training) in Chinese VLBW infants and to observe its effects on infants’ growth and development. Methods: Clinical data of 92 VLBW infants who were treated at the neonatal intensive care unit (NICU) of Loudi Central Hospital were retrospectively analyzed. The patients were grouped as the MEIR group (n=47) and controls (n=45). Physical and neurodevelopment development were compared between the two groups. Results: There were differences in height and weight and head circumference between the two groups at all corrected ages (all P<0.05). Abnormal motions, reflexes, muscular tension, audio-visual reactions, and posture, and the total numbers of abnormalities of 3-, 6-, 9- and 12-corrected month-old infants in the MEIR group were lower than in the control group (all P<0.05). The mental development index and psychomotor development index of 6- and 12- corrected month infants in the MEIR group were higher than in the control group (all P<0.05). Conclusion: MEIR could improve the physical and neurological developments of VLBW infants, reduce the incidence of adverse events, and improve their growth and development.