bluuebunny/crossref_metadata_2025 huggingface dataset:
Systematic Review for Knowledge Transfer at International Sport Mega-Events
Authors: Zhou Jingfan
Published: March 2023

Sport mega-events are characterized by a high degree of organizational complexity and are where games organizers take opportunities to strengthen their competencies and forge network connections via knowledge transfer. However, there is scarce evidence that the knowledge generated is transmitted between former and future host cities. This investigation aimed at examining the state of research on knowledge transfer at international sport mega-events. It followed the PRISMA protocol to identify critical research gaps and shed light on the barriers and enablers within this subject. Applying the quality and eligibility criteria yielded a final corpus of 11 academic and 6 non-academic works. The results demonstrate that a small group of scholars conducted empirical studies applying mixed research in this area. The three significant barriers were identified as the following: the Accessibility and Availability of Knowledge; the Lack of Absorptive Capacity; and the Dilemma of Knowledge Sharing and Knowledge Protection. Three crucial enablers were diagnosed as per the following: Knowledge Identifying and Tailoring Based on Needs, the Local Context, and Culture; Improving the Learning Culture and Capacities; and Communication, Cooperation, and Strategic Approach. The controversies among different studies also revealed the possible bias and insufficient knowledge transfer related to language, database, technology, geographic location, and priority setting, etc. We suggest further research focusing on specific cases between previous and future hosts.
The Effect of Physicochemical Properties and Surface Chemistry on CO2 Adsorption Capacity of Potassium Acetate-Treated Carbon Pellets
Authors: Hussin Farihahusnah , Hazani Nur Nadira , Aroua Mohamed Kheireddine
Published: March 2023

The aim of this study is to prepare a carbon pellet using low-cost material and a green process with excellent surface properties for carbon dioxide (CO2) capture application. To enhance the surface properties of the carbon pellet, a chemical activation method was introduced by modifying the pellet with potassium acetate. Then, the carbon pellet was tested in a packed-bed adsorption column to evaluate their performance for breakthrough time and CO2 adsorption. The effect of the physicochemical and surface chemistry of the carbon pellet on CO2 adsorption was also studied. The SEM image showed remarkable changes in the surface morphology of the carbon pellet after modification with potassium acetate. In addition, the presence of oxygen-containing functional groups such as hydroxyl and carbonyl groups in the modified carbon pellet could effectively enhance the CO2 adsorption capacity. Thus, it is proven that the carbon pellet modified with potassium acetate is suitable for CO2 adsorption. The results revealed that the CAC-PA 2M obtained the longest breakthrough time (19.4 min), higher adsorption capacity (0.685 mmol/g), and good recyclability (the regenerated sample can be reused for more than five cycles). The comprehensive characterization study and CO2 adsorption experimental data on new carbon pellets can provide a direction for new researchers that are venturing into the CO2 capture field.
Developing a Conceptual Framework Model for Effective Perishable Food Cold-Supply-Chain Management Based on Structured Literature Review
Authors: Akram Hafiz Wasim , Akhtar Samreen , Ahmad Alam , Anwar Imran , Sulaiman Mohammad Ali Bait Ali
Published: March 2023

This paper reviews the literature on perishable food cold-chain management (FCCM) in order to assess its current state, pinpoint its knowledge gaps, and suggest a framework for addressing the issues faced by this industry. This work examines 103 academic articles on the topic of the perishable food supply chain published in various journals between 2001 and 2022. Research publications were selected from two reputed databases—Scopus and Web of Science. The study finds that the current trend in FCCM is toward sustainable FCCM, which offers financial, ecological, and social benefits. However, sustainable FCC practices are more common in wealthy nations but are still lacking in developing countries. High lead times, costs, waste, order returns, complaints, and dissatisfied consumers are the results of a fragmented market and the associated proliferation of chain intermediates. The authors have also developed a conceptual framework based on the findings that illustrates the interconnected nature of the food cold-chain facilities, collaboration among food cold-chain (FCC) stakeholders, concern among FCC stakeholders, economic enhancement, fulfilment of FCC stakeholders’ responsibilities, and overall functioning of the FCC. This study may be helpful to FCC professionals, food regulators, government authorities, and researchers because it gives a concise picture of the state of research in the field.
Underutilized Vegetable Crops in the Mediterranean Region: A Literature Review of Their Requirements and the Ecosystem Services Provided
Authors: Platis Dimitrios P. , Papoui Eleni , Bantis Filippos , Katsiotis Andreas , Koukounaras Athanasios , Mamolos Andreas P. , Mattas Konstadinos
Published: March 2023

By 2050, the increasing demand for food will put additional pressure on natural resources. Underutilized crops, such as wild vegetables, are an essential component of the Mediterranean diet and are widely correlated with the traditional cuisine of Mediterranean countries. They could be widely associated with resistance to abiotic stress and enhanced genetic diversity, and could provide various ecosystem services. Their cultivation could support the Sustainable Development Goals (SDGs) established by the UN and the current EU policies related to environmentally friendly agriculture. Based on an extensive literature review, the aim of this paper is to summarize the environmental and ecological requirements of specific Mediterranean underutilized vegetables, the provisioning and regulating ecosystem services that could be derived from their cultivation, and their potential use. It is concluded that thorough planning of underutilized crop cultivation could enhance the provisioning and regulating ecosystem services that positively affect Mediterranean agriculture. However, further research should be carried out regarding their environmental and economic impact in order to assess the environmental and socio-economic effects of underutilized crops cultivation. This could lead to designing future policies that support underutilized crop cultivation and consumption.
Economic Policy Uncertainty: Does It Truly Matter?—Evidence from Corporate Fraudulent Behaviors in Chinese Capital Market
Authors: Wang Aiping , Dou Bin , Guo Xingfang , Hu Haifeng
Published: March 2023

A macro policy environment affects managers’ decision-making behaviors. When there is greater uncertainty in economic policy, will they engage in extreme violations? This paper explores the economic consequences of policy uncertainty at the firm level from the perspective of corporate fraud. We focus on the fraudulent behaviors of listed companies in the Chinese capital market and conduct our empirical research through the multiple mediation model. The results show that economic policy uncertainty not only has a direct effect on corporate fraud but it also has a mediating effect that can be explained by four mediating variables. Increased economic policy uncertainty will increase the likelihood of company fraud, and this direct effect will vary due to corporate heterogeneity. Companies with a lower risk tolerance and productive capacity will be more affected and have more significant violation motives. From the results of the mediating effect test, we determine that increased economic policy uncertainty increases mergers and acquisitions, decreases cash holdings, increases stock price volatility, and decreases institutional investors’ shareholdings, which will increase the possibility of corporate fraud.
Determination of Viscoelastic and Physicochemical Interactions of Dextran Type Exopolysaccharides (EPS) with Different Starch Samples
Authors: Gokcan Hande , Ozmen Duygu , Yildirim Yalcin Meral , Dertli Enes , Toker Omer Said , Sujka Monika
Published: March 2023

In this study, the rheological properties of three distinct dextrans with different levels of (1 → 6)-linked α-D-glucose/(1 → 3)-linked α-D-glucose units from three lactic acid bacteria (LAB) strains were determined. Dextran PDER21 was further selected following the rheological measurements and its interactions with maize, wheat and waxy maize starches were determined by characterizing the viscoelastic and pasting properties of the dextran–starch mixtures. Fourier transform infrared (FTIR) spectroscopy analysis was also applied to unveil this interaction. The presence of dextran PDER21 in the standard maize starch increased the elastic behavior, while its increased amounts enhanced the elastic properties of wheat and waxy maize starches. The temperature sweep test showed the solid-like property of starch–dextran mixtures in the studied temperature range (4–70 °C). Dextran PDER21 affected the pasting properties of starches. Especially, high levels of the peak, through and final viscosity values were reached with the blends of standard maize starch–1% dextran, wheat starch–0.5% dextran and waxy maize starch–0.5% dextran PDER21. Finally, the interactions were also confirmed by FTIR analysis as no alterations in the starch FTIR spectra were observed at different levels of dextran in different starch samples.
Elemental Behavior during Weathering and Pedogenesis of Clay-Rich Red Soils Developed in Different Lithologies in Java–Madura and Sulawesi in Indonesia
Authors: Beckford Howard Omar , Chang Cheng , Ji Hongbing
Published: March 2023

Clay-rich red soil profiles developed in different lithologies in Indonesia were assessed using geochemical evidence, the migration coefficient and elemental ratios. Our study aimed to ascertain the source of red soil materials and to investigate the elemental behavior in tropical soils. The results indicate carbonate profiles were derived from in situ weathering, while basalt profiles, even though having close affinity to their bedrock, also showed the contribution of external materials. Elemental behavior was dynamic with carbonate profiles indicating relatively constant depletion and even distribution. Basalt profiles indicated uneven distribution with enrichment and depletion. The variation in elemental behavior was linked to difference in lithologies, age and physiochemical conditions. Our findings support evidence of both residual and multiple source parent materials in red soil formation and provide insights into elemental behavior during weathering, while highlighting the influence of external materials’ contribution in deeply weathered tropical soils.
Evolutionary Game and Simulation Analysis of Participating Subjects in Remediation of Heavy Metal Contaminated Cultivated Land under the Ladder Multiple Supervision Model
Authors: Xiong Xiaoling , Li Jizhi , Lin Zejian
Published: March 2023

The heavy metal pollution of cultivated land in China is severe, requiring remediation. Introducing third-party governance subjects representing market resources is inevitable to realize the specialization and socialization of cultivated land remediation. However, due to the public nature of cultivated land, the confusion about participating parties’ responsibilities and difficulty coordinating interests restrict the expected effect of cultivated land remediation. To this end, a three-party evolutionary game model among the grassroots government, governance enterprises, and supervisory enterprises is constructed and virtually simulated, taking into account the influence of random checks by the higher-level government. We found that the reward and punishment mechanism of the grassroots government, the frequency of random inspection by the higher-level government, and the amount of deduction will influence the strategy selection of the participating parties. Strengthening the awareness of the responsibility of the grassroots government, optimizing the incentive system, establishing a regular spot-check system, and improving the cost of non-compliance by enterprises can effectively resolve conflicts of interest among the participants. The study results have practical significance for further enhancing the remediation efficiency of heavy metal-contaminated cultivated land.
Decomposition Analysis of Virtual Water Outflows for Major Egyptian Exporting Crops to the European Union
Authors: Mohy Samaa , El Aasar Khadija , Sakr Yasmin
Published: March 2023

International trade can spur economic growth, but it can also deplete the water resources needed to produce traded goods. This is crucial for Egypt as a lower-middle income country where boosting agricultural exports is encouraged to promote the sustainable agriculture development strategy. The objective of this paper was to quantify Egypt’s virtual water flows contributing to agricultural trade with one of its main trading partners, the European Union. We considered calculating virtual water of exports since 2001 as it represents Egypt-EU’s implementation of the association agreement. We focused on the five governorates of the Nile Delta. These governorates are major producers of the five major crops exported to the European Union. This study used long-term trade trends, and changes in crop composition to analyze the implications for virtual water outflows and economic water use efficiency. By decomposing the virtual water of exports, we were able to identify the trend of virtual water outflows and the factors affecting this trend. From both an economic and water perspective, our results suggest that adopting a policy aimed at saving water resources at the national level and focusing on high-yield exports at the international level will promote the development agenda of Egypt.
Seismic Overturning Fragility Analysis for Rigid Blocks Subjected to Floor Motions
Authors: Liu Hanquan , Huang Yong , Liu Xiaohui
Published: March 2023

This paper investigates the seismic rocking-overturning fragility of freestanding rigid blocks subjected to one-sine acceleration pulses from a probabilistic perspective. An equivalent single-degree-of-freedom (SDOF) model with a bespoke discrete damper is used to simulate the responses of four blocks with varying geometries under excitation with various characteristics. The simulation results are used to perform an overturning fragility analysis and evaluate the performance of various intensity measures (IMs). An IM strip, referred to as a hybrid strip, can be observed in the analysis, within which both safe rocking and overturning occur. For IM values outside of the hybrid strip, there exists a clear distinction between these two states. In this study, we introduce the hybrid ratio, a parameter that can estimate the size of the hybrid strip of different IMs. The hybrid ratio is defined as the combination of two ratios of hybrid strip width and the two IM strip widths corresponding to safe rocking and overturning, respectively. The effect of the different analysis strip widths is also examined in the overturning fragility analysis. The results suggest that the IM determined by excitation magnitude, frequency, and block geometry parameters demonstrates its superiority compared with some well-known IMs by having the smallest hybrid ratio and coefficient of variation, as well as good robustness of the overturning fragility curves against the change of the analysis strip width.
Studies on Biobased Non-Isocyanate Polyurethane Coatings with Potential Corrosion Resistance
Authors: Dhore Nikhil , Prasad Ermiya , Narayan Ramanuj , Rao Chepuri R. K. , Palanisamy Aruna
Published: March 2023

This work deals with the development of non-isocyanate polyurethane (NIPU) composites with an aniline oligomer, viz., tetraniline (TANI) for corrosion-resistant coatings. Firstly, epoxidizedsoyabean oil was converted to carbonated oil by inserting CO2 under high temperature and pressure into the epoxy ring. Then, varying weights of oligoaniline—0.5, 1, 2 and 4 wt % (based on the weight of CSBO)—were added to CSBO and cured with tetraethylenepentamine (TEPA, 25 wt % based on CSBO) at 80 °C for 12–15 h. The effects of oligomer loading on the thermal, mechanical and surface wetting properties of the free standing films were studied. The ATR-FTIR spectra of the films exhibited peaks corresponding to the bis-carbamate linkages, confirming the formation of urethane linkages. TGA analysis showed that the addition of oligoaniline did not alter the initial degradation temperature much; however, the residue increased with increasing loading of tetraniline. Both tensile strength and elongation (at break) increased with increasing oligoaniline content. While the glass transition temperature of the films was observed at approximately room temperature, i.e., 20–30 °C, for all the compositions, the contact angles of the composites were found to be less than that of the bare NIPU films. However, all the compositions were hydrophobic, exhibiting contact angles in the 98–110° range. SEM analysis of the cross-sections of the films confirmed the uniform distribution of tetraniline particles and surface morphology showed that the roughness increased with the loading of tetraniline from 0.5 to 4%. MS panels coated with NIPU exhibited good barrier properties and as loading of TANI increased, the rate of corrosion decreased. Salt spray tests indicated that oligoaniline improved the adhesion of the coating to MS and corrosion resistance compared to the neat NIPU coating.
An Experimental Study of Cavitation Bubble Dynamics near a Complex Wall with a Continuous Triangular Arrangement
Authors: Zheng Xiaoxiao , Wang Xiaoyu , Lu Xuan , Zhang Yuning , Zhang Yuning , Yu Jiaxin
Published: March 2023

The mechanism of cavitation cleaning of complex surfaces has received more and more attention. In the present paper, with the help of a high-speed photography experimental system, the dynamic behavior of a cavitation bubble in symmetrical positions near a complex wall with a continuous triangular arrangement is investigated. In terms of the bubble size and the initial wall–bubble distance, the non-uniform shrinkage of the bubble collapse and the movement characteristics of the bubble centroid are revealed. The main conclusions are as follows: (1) The collapse dynamic behavior of the bubble near a complex wall with a continuous triangular arrangement can be divided into three typical cases. (2) According to a large number of experimental results under different parameters, the parameter ranges corresponding to the three cases and the critical values between different cases are given. (3) The larger the bubble size is, or the smaller the initial wall–bubble distance is, the more significant the effect of the complex wall is, and the greater the movement distance towards the complex wall during the collapse stage.
Modeling DNA Methylation Profiles and Epigenetic Analysis of Safflower (Carthamus tinctorius L.) Seedlings Exposed to Copper Heavy Metal
Authors: Bölükbaşı Ekrem , Karakaş Mehmet
Published: March 2023

Heavy metals are chemical elements with high density that can be toxic or poisonous even at low concentrations. They are widely distributed in the environment due to industrial activities, mining, pesticide use, automotive emissions and domestic wastes. This study aimed to investigate the toxic effects of copper (Cu) heavy metal on safflower plants in terms of genetic and epigenetic parameters. Safflower seeds were exposed to different concentrations of Cu heavy metal solution (20, 40, 80, 160, 320, 640, 1280 mg L−1) for three weeks, and changes in the genomic template stability (GTS) and methylation pattern in the root tissues were analyzed using PCR and coupled restriction enzyme digestion-random amplification (CRED-RA) techniques. The results indicated that high doses of Cu have genotoxic effects on the genome of safflower plants. Epigenetic analysis revealed four different methylation patterns, with the highest total methylation rate of 95.40% observed at a 20 mg L−1 concentration, and the lowest rate of 92.30% observed at 160 mg L−1. Additionally, the maximum percentage of non-methylation was detected at 80 mg L−1. These results suggest that changes in the methylation patterns can serve as an important mechanism of protection against Cu toxicity. Furthermore, safflower can be used as a biomarker to determine the pollution in soils contaminated with Cu heavy metal.
Cellular Targets of HIV-1 Protease: Just the Tip of the Iceberg?
Authors: Centazzo Matteo , Manganaro Lara , Alvisi Gualtiero
Published: March 2023

Human immunodeficiency virus 1 (HIV-1) viral protease (PR) is one of the most studied viral enzymes and a crucial antiviral target. Despite its well-characterized role in virion maturation, an increasing body of research is starting to focus on its ability to cleave host cell proteins. Such findings are apparently in contrast with the dogma of HIV-1 PR activity being restricted to the interior of nascent virions and suggest catalytic activity within the host cell environment. Given the limited amount of PR present in the virion at the time of infection, such events mainly occur during late viral gene expression, mediated by newly synthesized Gag-Pol polyprotein precursors, rather than before proviral integration. HIV-1 PR mainly targets proteins involved in three different processes: those involved in translation, those controlling cell survival, and restriction factors responsible for innate/intrinsic antiviral responses. Indeed, by cleaving host cell translation initiation factors, HIV-1 PR can impair cap-dependent translation, thus promoting IRES-mediated translation of late viral transcripts and viral production. By targeting several apoptotic factors, it modulates cell survival, thus promoting immune evasion and viral dissemination. Additionally, HIV-1 PR counteracts restriction factors incorporated in the virion that would otherwise interfere with nascent virus vitality. Thus, HIV-1 PR appears to modulate host cell function at different times and locations during its life cycle, thereby ensuring efficient viral persistency and propagation. However, we are far from having a complete picture of PR-mediated host cell modulation, which is emerging as a field that needs further investigation.
Epstein–Barr Virus History and Pathogenesis
Authors: Yu Hui , Robertson Erle S.
Published: March 2023

Epstein–Barr virus (EBV) is the first identified human oncogenic virus that can establish asymptomatic life-long persistence. It is associated with a large spectrum of diseases, including benign diseases, a number of lymphoid malignancies, and epithelial cancers. EBV can also transform quiescent B lymphocytes into lymphoblastoid cell lines (LCLs) in vitro. Although EBV molecular biology and EBV-related diseases have been continuously investigated for nearly 60 years, the mechanism of viral-mediated transformation, as well as the precise role of EBV in promoting these diseases, remain a major challenge yet to be completely explored. This review will highlight the history of EBV and current advances in EBV-associated diseases, focusing on how this virus provides a paradigm for exploiting the many insights identified through interplay between EBV and its host during oncogenesis, and other related non-malignant disorders.
The Future of Clinical Phage Therapy in the United Kingdom
Authors: Jones Joshua D. , Trippett Clare , Suleman Mehrunisha , Clokie Martha R. J. , Clark Jason R.
Published: March 2023

Bacteriophage (phage) therapy is a promising alternative antimicrobial strategy with the potential to transform the way bacterial infections are treated. In the United Kingdom, phages are classed as a biological medicine. Although no phages are licensed for UK use, they may be used as unlicensed medicinal products where licensed alternatives cannot meet a patient’s clinical needs. In the last 2 years, 12 patients in the UK have received phage therapy, and there is burgeoning clinical interest. Currently, clinical phage provision in the UK is ad hoc and relies upon networking with international sources of phages. The provision of phage therapy in the UK will not progress beyond an increasing number of ad hoc cases until an onshore sustainable and scalable source of well-characterised phages manufactured in accordance with Good Manufacturing Practice (GMP) is established. Here, we present an exciting new collaboration between UK Phage Therapy, the Centre for Phage Research at University of Leicester, CPI, and Fixed Phage. These partners, and others as we develop, will establish sustainable, scalable, and equitable phage therapy provision in the UK. We set out a vision for how phage therapy will be integrated into the NHS and healthcare more broadly, including the complementarity between licensed (cocktail) and unlicensed (personalised) phage preparations. Key elements of phage therapy infrastructure in the UK will be GMP phage manufacturing, a national phage library, and a national clinical phage centre. Together, this infrastructure will support NHS microbiology departments to develop and oversee phage therapy provision across the UK. As it will take time to deliver this, we also describe considerations for clinicians seeking to use unlicensed phage therapy in the interim. In summary, this review sets out a roadmap for the delivery of clinical phage therapy to the UK, the benefits of which we hope will reverberate for patients for decades to come.
Hydrochemical Characteristics of Mine Water and Their Significance for the Site Selection of an Underground Reservoir in the Shendong Coal Mining Area
Authors: Guo Yangnan , Li Guoqing , Wang Lei , Zhang Zheng
Published: March 2023

Underground reservoir technology can mitigate water shortage and pollution problems in water shortage coal mining areas and has a good application prospect. While still a new technology, the theory and method of underground reservoirs need to be improved. This research focused on the hydrochemical characteristics of mine water and their significance for the site selection of underground reservoirs. With the Shendong coal mining area as a case study, the hydrochemical major ions, toxicological indexes, and stable isotopes of hydrogen and oxygen were tested for the mine water samples, and the water quality was quantitatively evaluated and the origins of over-limit variables were investigated by hydrogeochemical numerical simulation and ionic ratio analysis. The influencing factors of water quality were analyzed and the significance of mine water quality for the site selection of underground reservoirs was discussed. The results show that the main over-standard variables are Na+, F−, SO42−, TDS, and sodium ion adsorption ratio (SAR), and a strong positive correlation exists between F− and SAR and a negative correlation exists between F− and Ca+. Na+ in mine water originates from the dissolution of halite and silicate rocks, as well as reverse cation exchange. F− originates from reverse cation exchange and the displacement between OH− in alkaline water and F− adsorbed on the surface of minerals. On the whole, the mine water quality is better on the east than on the west of the WL River. The water–rock interactions in goaf increase the concentrations of F− and Ca2+ and SAR. The areas where the mine water samples have low concentrations of Na+, F−, and low SAR values, such as the shallow coal seams at the SGT, DLT, and WL mines, are favorable sites for the underground reservoir. The outcomes may benefit the reasonable site selection of underground reservoirs in similar coal mining areas with water shortage.
Evaluation of Hydraulics and Downstream Fish Migration at Run-of-River Hydropower Plants with Horizontal Bar Rack Bypass Systems by Using CFD
Authors: Zöschg Hannes , Dobler Wolfgang , Aufleger Markus , Zeiringer Bernhard
Published: March 2023

Anthropogenic structures often block or delay the downstream migration of fish in rivers, thereby affecting their populations. A potential solution at run-of-river hydropower plants (HPPs) is the construction of a fish guidance structure in combination with a bypass system located at its downstream end. Crucial to fish guidance efficiency and thus to fish behavior are the hydraulic flow conditions in front of the fish guidance structure and upstream of the bypass entrance, which have not thus far been investigated in depth. The present study aims to extend the knowledge about the flow conditions at these structures. Based on the results of 3D numerical simulations of two idealized block-type HPPs with horizontal bar rack bypass systems, the flow conditions were examined, and the fish guidance efficiency was predicted. Herein, a new method was used to represent the fish guidance structure in the numerical model. The results show that the approach flow to fish guidance structures at block-type HPPs varies significantly along their length, and areas with unfavorable flow conditions for downstream fish migration frequently occur according to common guidelines. Subsequently, eight variations were performed to investigate the effect of key components on the flow field, e.g., the bypass discharge. Finally, the results were compared with literature data and discussed.
Differentials in Maternal Mortality Pattern in Sub-Saharan Africa Countries: Evidence from Demographic and Health Survey Data
Authors: Okonji Osaretin Christabel , Nzoputam Chimezie Igwegbe , Ekholuenetale Michael , Okonji Emeka Francis , Wegbom Anthony Ike , Edet Clement Kevin
Published: March 2023

Maternal mortality ratios in sub-Saharan Africa remain high and worrisome. Moreover, maternal health indicators have remained poor despite large efforts in the last two decades. This study assesses maternal mortality patterns by age and country. The demographic and health survey data were used for the study. Based on the results, countries with the lowest adult female mortality rate include Senegal, Comoros, Rwanda, Mauritania, Sao Tome and Principe, Gambia, and Ethiopia. In addition, Chad (44.7%), Niger (38.7%), the Congo Democratic Republic (34.8%), Nigeria (34.2%), Mauritania (32.0%), Senegal (29.2%), Liberia (28.8%), Benin (27.8%), and Guinea (27.5%), respectively, reported the highest female deaths that are pregnancy-related. Overall, Lesotho (1024; 95% CI: 731–1318), Liberia (913; 95% CI: 638–1189), Chad (860; 95% CI: 728–993), Congo Democratic Republic (846; 95% CI: 690–1003), Sierra Leone (796; 95% CI: 632–960) and Guinea (724; 95% CI: 531–916) had the leading pregnancy-related mortality ratio per 100,000 live births. The study found that the patterns of death vary across different countries. There is a need for concerted efforts to reduce pregnancy-related deaths in sub-Saharan countries.
Kur dingo Gandingos miestas? Arba Plungės miestelio pradžia XVI a. antroje pusėje
Authors: Drungilas Jonas
Published: March 2023

WHERE THE TOWN OF GANDINGA DISAPPEARED, OR THE BEGINNING OF THE TOWN OF PLUNGĖ IN THE SECOND HALF OF THE SIXTEENTH CENTURY

The article examines the beginnings of the town of Plungė, which was established in the second half of the sixteenth century in the western part of the Samogitian Upland.
The names of the town of Gandinga and of the town of Plungė that later replaced it, which appear in the sources from that time, are analysed with the help of historical, geographical, and linguistic data, thus reconstructing the early stage of the development of Plungė.

KEYWORDS: Mikołaj Dorohostajski, Gandinga, city, town, fort hill, Plungė.
The influence of immunogenetic markers of bulls of different breeds on the milk productivity of their daughters
Authors: КИСЕЛЕВ И.А. , КУЗЯКИНА Л.И. , ТЯПУГИН С.Е.
Published: March 2023

В результате анализа частоты встречаемости иммуногенетических маркеров систем L и M групп крови у быков-производителей разных пород установлено, что система L присутствовала у быков айрширской, красно-пестрой и холмогорской пород, а система М — у быков-производителей красно-пестрой и холмогорской пород. Частота встречаемости данных систем составила от 8 до 80%. Система L быков-производителей положительно связана с продуктивностью их дочерей по удою (r=+0,13) и по массовой доле жира в молоке (r=+0,25). Система М — наоборот, отрицательно: r=-0,27 и r=-0,24 соответственно. Наличие систем групп крови L и М у быков красно-пестрой породы оказывает положительное влияние на удой их дочерей — от 529 до 722 кг, а по массовой доле жира в молоке — от 0,02 до 0,14%. Система М у холмогорского скота достоверно снижает удой на 422 кг, массовую долю жира в молоке — на 0,08%. Иммуногенетические маркеры по системам групп крови быков-производителей могут быть «индикаторами» уровня продуктивности дочерей. Их можно использовать как дополнительный критерий отбора и подбора животных.
Телеіндустрія США 20-50-х років ХХ століття: становлення та динаміка розвитку
Authors: Печеранський Ігор
Published: March 2023

Завданням статті є аналіз витоків та основних віх у контексті динаміки розвитку американської TV-індустрії у 20–50-х роках ХХ століття. З’ясовано, що впродовж зазначеного періоду нетворкінг стає відмітною ознакою американської медіасцени, а більшість комерційних телерадіостанцій групується під егідою національних мовних мереж (NBC, CBS, ABC). Стверджується, що економічна логіка ефірної індустрії (продаж реклами) диктувала динаміку змін під час наповнення форм і структурування TV-контенту. Доведено, що саме комерціалізація визначила образ американського TV і пов’язаної з ним індустрії, заклавши підвалини олігополії на національному телевізійному ринку США, яка, безперечно, вплинула на його розвиток у другій половині ХХ–на початку ХХІ ст.
Естрадне мистецтво в Незалежній Україні: стан і перспективи розвитку в ХХІ столітті
Authors: Кочержук Денис
Published: March 2023

Розглянуто особливості становлення естрадного мистецтва в період Незалежності України (дослідження активного розвитку естрадного музичного мистецтва розкрито в етапі від 2010 року ХХІ ст. – по теперішній час). Визначено головні передумови, що суттєво вплинули на формування україномовного контенту в музичному суспільстві. Надано загальну характеристику основних періодів появи тотальної українізації у мистецькому просторі. Проаналізовано творчу діяльність видатних українських митців (композиторів і виконавців) у зародженні нових та сучасних формотворчих концепцій відображення українських музичних творів.
Um estudo sobre a condição e a qualidade de vida pautado no enfoque biopsicossocial após o impacto causado pela pandemia de Covid 2019
Authors: Schotten Paulo César , Da Silva Amanda de Souza , De Oliveira Sidinéia Andrade , Bueno Tainara dos Santos
Published: March 2023

Para que as pessoas desempenhem tarefas com alta qualidade, as organizações precisam se preocupar com a qualidade de vida de seus funcionários quer seja nos aspectos biológicos, psicológicos ou sociais. O objetivo da pesquisa foi estudar a qualidade de vida dos empregados do comércio na região do Vale do Ivinhema, MS. Bibliograficamente foram apresentados estudos sobre qualidade de Vida no Trabalho e o enfoque Biopsicossocial. Metodologicamente, essa pesquisa foi classificada como qualitativo quanto aos métodos de análise, descritivo quanto aos objetivos e como levantamento de dados em relação aos procedimentos técnicos. Foi possível identificar e analisar as condições dos profissionais que ficaram abalados fisicamente, mentalmente, psicologicamente, devido as frustações, ansiedade, medo, trauma, entre outros sintomas causados pela pandemia.
Percepção de gestantes acerca das complicações da infecção por Zika Vírus: revisão de literatura
Authors: Lima Girlane de Melo , Da Silva Teodoro Marcelino , de Albuquerque Fideralina Rodrigues , de Alencar Francisca Silva , Rodrigues Vitor Silva , Barbosa Érica de Lavor , De Andrade Rafael Rufino Melo Paes , De Araújo Moziane Mendonça , Alves e Silva Ronny de Tarso , De Holanda Júnior Pedro Henrique , Bragato Aline Guarato da Cunha , Arrais Regina Maria Mota
Published: March 2023

Objetivou-se, evidenciar à luz da literatura científica, a percepção de gestantes acerca das complicações da infecção por zika vírus. Trata-se de revisão narrativa da literatura, do tipo descritiva-exploratória. A busca de dados foi realizada no período de outubro a novembro de 2022, de forma pareada e independente por dois pesquisadores nas bases de dados indexadas a BVS. Foram aplicados os seguintes filtros; artigos completos, disponíveis para download e leitura na íntegra; publicados nos três idiomas (português, inglês e espanhol). Salienta-se que neste estudo não será delimitado o recorte temporal de publicação dos artigos identificados, visto que buscou-se elevar abrangência da busca. Foram incluídos os artigos que versassem acerca da temática em estudo, excluindo as duplicatas, os resumos e relatos de experiências. Assim, obtiveram-se dez artigos para compor amostra final. Mediante o processo analítico dos estudos, evidenciou-se que as gestantes reconhecem que a infecção pelo Zika vírus, é uma doença que poderá repercutir negativamente na saúde materna-fetal e no desenvolvimento da gestação, podendo propiciar graves complicações, principalmente para os fetos. Portanto, faz-se necessário na implementação de cuidados pré-natais integrais, holísticos e, sobretudo de qualidade que visem a prevenção e controle do zika vírus, em especial durante a gravidez.
A construção de novos mundos através do som. Estudo de caso do game para dispositivos móveis DarkEcho
Authors: Lafetá Júlio César Alessi de Carvalho
Published: March 2023

Este trabalho propõe um estudo de caso do game DarkEcho, para dispositivos móveis, no qual a interface gráfica é articulada prioritariamente pela linguagem sonora, o que é incomum, já que no universo dos games a imagem tem maior destaque, ficando o som geralmente em segundo plano. Na análise do jogo, foram levantadas diversas possibilidades do uso do som na mediação do processo audiovisual, na recriação de um mundo de terror e suspense, em um processo de remediação e alusão a diversos símbolos do gênero através de uma experiência sonora imersiva e interativa.
Apendicite Aguda: aspectos etiopatogênicos, métodos diagnósticos e a apendicectomia videolaparoscópica como manejo
Authors: Radd Luis Gustavo Amaral , Carreiro Luíza Filizzola Carabetti , Alves Marco Túlio Saldanha Victor , Machado Mariana Campos Duarte , Campos Lívia Oliveira , De Oliveira Marcelo Gonçalves , Casséte Lucas de Carvalho , Rocha Maria Clara Brant , Lamego Luiz Lorentz Salzmann
Published: March 2023

A apendicite aguda consiste na inflamação do apêndice cecal, que ocorre em decorrência de uma obstrução luminal, a qual pode ser resultado da presença de fecalitos, fezes impactadas, corpos estranhos ou neoplasias. Devido a isso, há uma distensão do órgão e consequente transmissão nervosa intensa, a qual é responsável pela dor característica. Tal patologia pode ser classificada em complicada ou não complicada, a depender do estágio evolutivo do quadro, o que irá influenciar diretamente na decisão do manejo terapêutico mais adequado. Em virtude da variedade etiológica da apendicite aguda, a epidemiologia é bastante variada, e a incidência depende de diversos fatores, sendo que fatores genéticos e histórico familiar caracterizam condições que predispõem ao quadro. Além disso, a depender da etiologia da apendicite e da evolução do quadro, as manifestações clínicas e o prognóstico são diferentes. No que tange ao diagnóstico, esse é, frequentemente, realizado de maneira clínica, quando depara-se com a seguinte tríade: dor abdominal no quadrante inferior direito ou migratória, anorexia e náuseas e/ou vômitos. Todavia, ele pode ser confirmado através do exame físico, associado a parâmetros laboratoriais de inflamação e exames imagiológicos de ultrassom, tomografia computadorizada ou ressonância magnética sugestivos. O manejo terapêutico precoce é imprescindível, a fim de evitar possíveis complicações para o paciente. Sabe-se que a apendicectomia laparoscópica consiste no método padrão-ouro para o tratamento da apendicite aguda, devido a sua baixa invasividade, segurança e recuperação pós operatória mais rápida. Todavia, apesar dos benefícios, é de extrema relevância uma investigação pré operatória adequada, a fim de descartar possíveis diagnósticos diferenciais e evitar iatrogenia.
Doença Celíaca: aspectos epidemiológicos, fisiopatológicos e manejo terapêutico
Authors: Nascimento Francis Henrique , Magalhães Ana Clara Felipe , Campos Isadora Afonso de Oliveira , Chávare Jéssica , Machado Kecyanne Malheiros , Ribeiro Helen Bortolote , Beccaro Miguel Chávare , Silva Leonardo França Alves , Coelho Mateus dos Santos , De Almeida Juliana Barbosa
Published: March 2023

A doença celíaca (DC) é uma doença autoimune caracterizada por alterações intestinais associadas com a expressão de linfócitos T em indivíduos geneticamente predispostos que fazem a ingestão de glúten. A DC afeta aproximadamente 1% da população mundial. Suas manifestações clínicas clássicas aparecem nos primeiros dois anos de idade, enquanto seu segundo pico ocorre entre os 20 e 30 anos. A fisiopatologia da DC é uma interação entre a genética e o ambiente. Indivíduos com genes mais propensos à intolerância parcial à gliadina presente no glúten são indivíduos que possuem essa predisposição para DC. Assim, quando expostas aos derivados do glúten, as células T sensíveis tornam-se ativas, causando inflamação e atrofia da mucosa do intestino delgado, o que leva à má absorção. A maioria dos pacientes com DC não apresentam sintomas, todavia, os sintomas da DC, quando presentes, podem ser encontrados nos intestinos, em outras partes do corpo ou em ambos. Ademais, podem haver complicações em diferentes gravidades tanto para homens quanto para mulheres. O diagnóstico da DC requer uma associação de fatores. Considera-se que a DC possui três pilares que ajudam a confirmar sua presença: testes sorológicos, histologia duodenal e testes dietéticos. Estes são os maiores responsáveis ​​pelo diagnóstico final da doença. O tratamento mais eficaz para DC é a remoção do glúten da dieta, juntamente com um monitoramento dietético rigoroso e mudanças no estilo de vida.
Diabetes Mellitus Tipo 2 - aspectos epidemiológicos, fisiopatológicos e manejo terapêutico
Authors: Dos Santos Vitor Cardoso , Rodrigues Ana Luíza Cardoso , Cajazeira Brenda Carolina Rodrigues , Ferrari Caroline Anastácio , Libanio Gabriela Cristina , Sanabria Thays Lacerda , Guimarães Alice de Faria , Isaac Yasmin Bulkool
Published: March 2023

O diabetes mellitus tipo 2 (DM2) é uma síndrome metabólica global em ascensão, caracterizada por resistência à insulina e níveis elevados de glicose no sangue. Quanto à epidemiologia, é um problema de saúde pública em rápido crescimento, com prevalência estimada de 90-95% dos pacientes diabéticos. Estimativas da Organização Mundial da Saúde (OMS) preveem que 693 milhões de adultos vivendo com a patologia até 2045. Sua prevalência é maior em pessoas do sexo masculino, mais suscetivel em etinia asiática e predominante na população urbana. Quanto à fisiopatologia, DM é um distúrbio metabólico caracterizado por hiperglicemia crônica, que pode levar a complicações agudas e crônicas. Os tipos mais comuns são Diabetes Mellitus Tipo 1 (DM1), o Diabetes Mellitus Tipo 2 (DM2) e o Diabetes Mellitus Gestacional (DMG). Quanto às manifestações clínicas, os pacientes portadores de DM2 frequentemente não apresentam sintomas na fase inicial, o que dificulta o diagnóstico precoce. Quando presente, os sintomas da DM2 incluem poliúria, polidipsia, polifagia, formigamento e perda de peso não intencional. Estes sintomas também estão presentes na DM1. Sua identificação depende de uma anamnese minuciosa, um exame físico bem detalhado e exames complementares. Para diagnóstico definitivo, lança-se mão da glicemia plasmática de jejum, teste oral de tolerância à glicose (TOTG), hemoglobina glicada (A1c) e glicemia ao acaso, fornecendo mais detalhes com melhor acurácia para, juntamente com os dados clínicos, obter o diagnóstico. Já a abordagem terapêutica, apresenta-se através do manejo farmacológico e mudança de hábitos e estilo de vida. Existem quatro grupos principais de medicamentos antidiabéticos: biguanidas, secretagogos de insulina, sensibilizadores de insulina e insulina ou seus análogos que vão atuar com mecanismos diferentes para controlar o diabetes.
Efeito da densidade na bandeja e do volume do recipiente sobre o crescimento de mudas de Canafístula (Peltophorum dubium)
Authors: Massad Marília Dutra , Dutra Tiago Reis , Meireles Ivan Edson da Silva , Dos Santos Aline Ramalho , Menezes Eduarda Soares , Sarmento Mateus Felipe Quintino
Published: March 2023

O trabalho teve como objetivo avaliar o efeito da densidade na bandeja e do volume do recipiente sobre o crescimento da canafístula, em condições de viveiro. O experimento foi conduzido em delineamento de blocos ao acaso, com três repetições, no esquema fatorial (5 x 2), sendo avaliados cinco densidades de mudas na bandeja, 54, 36, 27, 18 e 9 mudas, que correspondem a 2604 cm2, 1736 cm2, 1302 cm2, 868 cm2 e 434 cm2 de área ocupada por mudas, respecitvamente e dois volumes  de  tubetes (180  e  280  cm³) totalizando  10  tratamentos. Avaliaram-se a altura (H), diâmetro do colo (DC) e a relação entre as duas variáveis. As mudas de canafístula produzidas nos recipientes de maior volume (280 cm3) apresentaram valores superiores para altura e relação H/DC. A maior densidade de mudas de canafístula na bandeja proporcionou às plantas maior crescimento em altura e na relação H/DC, sendo recomendada a utilização de 100% da área útil da bandeja na produção de mudas da espécie.
Axiologias sobre liberdade em raps produzidos por adolescentes em cumprimento de medida socioeducativa
Authors: Abril Angelica
Published: March 2023

A partir de uma perspectiva interdisciplinar, coadunamos referenciais teóricos do campo educacional e da teoria sociológica e dialógico-enunciativa do Círculo de Bakhtin, para analisar axiologias sobre liberdades mobilizadas em letras de raps produzidos por adolescentes em cumprimento de medida privativa de liberdade no contexto da socioeducação. A produção dos raps é responsiva à aplicação de um projeto, cujo objetivo visou ampliar os horizontes apreciativos dos adolescentes sobre o tema liberdade. Assim, concretizou-se a escuta alteritária dos adolescentes a respeito das mudanças nas concepções de liberdade. Na visão metodológica de Bakhtin, as Ciências Humanas, que tratam da criação ideológica, buscam compreender como ela se manifesta nos enunciados que mobilizam discursos em gêneros discursivos. Tomam-se como unidades de analise os raps produzidos, buscou-se compreender a manifestação responsiva dos adolescentes. Os resultados apontam que os discursos desses adolescentes sobre liberdade se constroem axiologicamente nas letras de raps, a partir de tensões entre a responsabilização, aceitação da punição, o desejo de superação, de mudança de vida, a esperança e a manifestação de fé.
Análise da utilização de fibra de coco em concreto estrutural
Authors: Andrade Ana Paula Fonseca , Andrade Júlia Brenda Mota , Barbosa Laíza Carla Vieira , De Araújo Lorenna Borba Lopes , Lucas Ully Costa Pinto , Castro Luciana Dias Martins da Costa
Published: March 2023

A construção civil é a principal responsável pela produção e consumo do concreto, portanto, é necessário o estudo de alternativas que visem diminuir os impactos causados por ele no meio ambiente.  A adição de fibras em concreto com a finalidade de melhorar sua resistência pode ser considerada algo novo, em especial, as fibras de coco. Buscando compreender como a fibra de coco pode contribuir com a sustentabilidade, esta pesquisa analisou o desempenho e a trabalhabilidade do concreto com a adição da fibra por meio da avaliação das propriedades físicas e mecânicas, da resistência à compressão e à tração por compressão diametral, e ensaios de microscopia eletrônica. Para as análises, foram desenvolvidos três tipos de concreto, um referencial — sem adição de fibra — e outros dois com porcentagens distintas de fibras, 5,0% e 10,0%. Foi observado que a porcentagem de 5,0% foi a que teve melhor desempenho, e que a de 10,0% também obteve um resultado satisfatório, sendo esta a porcentagem mais recomendada por contribuir mais com a sustentabilidade.