bluuebunny/crossref_metadata_2025 huggingface dataset:
Hak Kepemilikan Komunal dalam Indikasi Geografis
Authors: Taufitra Ayang Ayu , Kurniawan I Gede Agus
Published: May 2023

Urgensi dari penelitian ini adalah upaya untuk mengkaji IG dalam perspektif globalisasi hukum. Penelitian ini bertujuan untuk menganalisis hakikat hak kepemilikan komunal dalam IG serta eksistensi hak kepemilikan komunal IG dalam perspektif globalisasi hukum. Penelitian ini merupakan penelitian hukum normatif dengan pendekatan konsep dan perundang-undangan. Hasil penelitian menunjukkan bahwa Hakikat hak kepemilikan komunal dalam IG sejatinya belum mendapatkan pengaturan secara spesifik baik dalam Paris Convention 1883, Madrid Agreement 1891, Trips Agreement, hingga Lisbon Agreement (1958 dan 1967) serta UU IG. Meski begitu, secara implisit, esensi hak kepemilikan komunal dalam IG sejatinya menjadi orientasi utama bagi IG, khususnya dalam menegaskan IG sebagai hak kekayaan intelektual dengan karakteristik khusus yang berbasis pada hak kepemilikan komunal masyarakat. Eksistensi hak kepemilikan komunal IG dalam perspektif globalisasi hukum sejatinya masih lemah dan perlu diperkuat. Hal ini dapat dilakukan dengan melakukan revisi atas berbagai ketentuan internasional seperti Paris Convention 1883, Madrid Agreement 1891, Trips Agreement, hingga Lisbon Agreement (1958 dan 1967) yang menegaskan bahwa hak kepemilikan komunal merupakan esensi utama dari IG. Selain itu, revisi terhadap UU IG di Indonesia juga perlu dilakukan untuk menegaskan hak kepemilikan komunal IG tentu dengan melibatkan partisipasi masyarakat untuk sadar akan IG dan memiliki kesadaran untuk mendaftarkan hak kekayaan intelektual berupa IG secara kolektif.
Vieussens’ Arterial Ring with Coronary Artery Disease: Affecting Clinical Decision Making
Authors: Zoumi Eleni Angeliki , Gower Hannah , Van Lingen Robin , Edwards Andrew , Devadathan Sen
Published: May 2023

Background:
Incidental findings on imaging are becoming increasingly common. An example of such a finding is a Vieussens’ arterial ring. It was first described by Raymond de Vieussens as a collateral pathway between the conus branch of the right coronary artery and the proximal right ventricular branch of the left anterior descending coronary artery. This finding can be of significance in patients with coronary artery disease.

Case Presentation:
The authors present the case of a 79-year-old male who experienced atrial tachyarrhythmia with a complex coronary artery fistula between the left anterior descending artery, conus branch, and the main pulmonary artery, indicating a Type Ib Vieussens’ arterial ring. Type Ib means that it is accompanied by vascular pathology. The patient also had additional coronary disease in the left anterior descending artery, further increasing the complexity of the case.

Conclusion:
Coronary collaterals offer an alternative source of blood supply in cases of additional coronary artery disease and can impact patient prognosis. Chronic myocardial ischaemia and increased shear stresses are causes of collateral circulations. Vieussens’ arterial rings can be subdivided into four groups. Only one case report of a Type Ib Vieussens’ ring has been identified on literature review, where the patient presented with a non-ST elevation myocardial infarction, unlike the atrial tachyarrhythmia in this case. Given their rarity, specifically of Type Ib, there is increased difficulty in establishing an appropriate management pathway, thus having great impact on clinical decision making.
Mathematics smart books based on QR Code as a digital learning media material limit function
Authors: Kristiawati Kristiawati , Wangsa Arma , Fatmasari Putri , Usman Muhammad Rizal
Published: May 2023

Based on research data conducted by Cambridge International through the Global Education Census, it is stated that 67% of Indonesian students use smart phones in class, while 90% of teachers in Indonesia still use blackboards when teaching. Through this research, produced a learning medium, namely Smart Book based on QR Code, which allows students to more easily access digital learning materials so that they can adapt to the habits of students in class. The type of research used is Research Development with a 3D model (Design, Develop, and Deliver) and two data analysis techniques, namely: validity data analysis and student response data analysis. The procedure for making QR Code-Based Math Smart Books relies on the functions of several technologies, namely: QR Code, QR Scanner, and Google Drive. After the manufacturing process, media validation and material validation were carried out. The results of media and material validation showed the validity level of 3.83 and 4 which were in the very feasible category. Based on the results of the trial with 6 respondents, the students responded well. Therefore, based on validation and trials, it can be concluded that the Smart Mathematics Book media can overcome student learning gaps where students use smartphones more often in class.
Introduction
Authors: Utterson Andrew
Published: May 2023

In the wake of the oft-presumed demise and obsolescence of cinema, its past continues to find presence in the present. Yet, if the memory of cinema persists, it does so in technologically and otherwise reconfigured forms, requiring increasingly creative conceptions of history and time. For the historian attuned to these altered states, contemporary cinema tells its own history (or histories). After all, as this book illustrates in its specific case studies, cinema – including its cumulative archive of images – has demonstrated a remarkable resilience, an unwillingness to be buried or forgotten, resonating in the present in the most surprising and illuminating of ways....
The Movie Theatre as Haunted Space: Shirin and 70×70
Authors: Utterson Andrew
Published: May 2023

This chapter focuses on the shifting significations associated with the movie theatre as a symbol of architecture and apparatus, the cinematic experience and its trace. Abbas Kiarostami's Shirin (2008), and its meta-cinematic representation of the movie theatre, is considered in mapped dialogue with a broadly contemporaneous curatorial project that documents through psychogeography (Guy Debord) the mnemonic resonances of moviegoing, past and present. Comparisons are drawn between the anonymous patrons of Kiarostami's movie theatre in Shirin as reflexive phantasm and the relocation of a site-specific phenomenology to the streets of London, as documented in Iain Sinclair's 70x70: Unlicensed Preaching: A Life Unpacked in 70 Films (2014), a cine-biography and related project of site-specific screenings. The focus is on charting cinematic cartographies as spatialised media archaeology that brings memory and experience into historical and historiographic focus.
Recalling the Past Lives of Cinema: Uncle Boonmee Who Can Recall His Past Lives
Authors: Utterson Andrew
Published: May 2023

This chapter considers questions of materiality by looking back at the film-to-digital transition as textually refracted in historiographic analogy. Specifically, this chapter investigates the intertwined technological, ontological and historical status of a filmic base, i.e., photochemical film or celluloid, precisely as it came to exist as a principally historical medium, replaced by digital formats. Ideas of corporeal finitude and material obsolescence are explored through Apichatpong Weerasethakul's Uncle Boonmee Who Can Recall His Past Lives (Loong Boonmee raleuk chat, 2010), in terms of its representations of transmigration and reincarnation, with a particular focus on its use of Super 16mm film at a time in film history when photochemical film of all kinds was experiencing its own existential transformation. This formal strategy serves as the starting point for an exploration of a cinematic life cycle (often referred to in terms of the death of cinema) that includes, but also exceeds the historiographic conceptions or tropes of birth and death.
Shakespeare, Montaigne and Ricoeur: Identity as Narrative
Authors: Bečanović-Nikolić Zorica
Published: May 2023

Although the work of Paul Ricoeur has seldom been brought to shed light on the writings of Montaigne or Shakespeare, Ricoeur’s phenomenology of self and time from Time and Narrative helps significantly to illuminate these authors’ representations of real and fictional selves. For Ricoeur, the problem of the self’s perpetual mutability can only be solved through narration and emplotment. Just as Montaigne creates his own identity in essayistic narration, so various Shakespearean characters do the same: Hamlet, Prospero, Othello, Macbeth, Richard II, and even King Lear can be seen as conspicuous examples of self-making through narrative. Ricoeur's investigation of the intersubjective nature of selfhood in Oneself as Another further clarifies the narrative identity thet we encounter in Montaigne and Shakespeare. Finally, Ricoeur's consideration of the external other as crux of the self's ethical existence is shown as notably relevant for understanding concepts of identity found in the two early modern authors.
Cavell’s Tragic Scepticism and the Comedy of the Cuckold: Othello and Montaigne Revisited
Authors: Miura Cassie M.
Published: May 2023

This chapter challenges the intrinsic connection that Stanley Cavell posits between philosophical scepticism and tragedy in Shakespeare’s plays by expanding on the suggestion in Cavell's essay ‘Othello and the Stake of the Other’ that Montaigne offers a different approach from Shakespeare to questions of doubt, sexual jealousy and witchcraft. Like Shakespeare, Montaigne draws a connection between philosophical scepticism and male anxieties about marriage, but Montaigne’s account of a happy cuckold circumvents the tragic outcomes of the play Othello. While Cavell looks to modernity, specifically Hollywood comedies of remarriage, for a resolution to what he calls the “problem of scepticism,” this chapter argues that Montaigne’s comic approach to scepticism and consequent affirmation of the philosophical end of tranquillity reveals such a resolution already at play during the early modern period.
Feeling Indifference: Flaying Narratives in Montaigne and Shakespeare
Authors: Calhoun Alison
Published: May 2023

This chapter looks at some of the striking resonances between flaying narratives in Shakespeare’s King Lear and Montaigne’s essays “On virtue” and “On experience,” focusing on how both authors respond to an ambiguous tale about skinning found in biographical sources for Skepticism’s figurehead, Pyrrho. This Pyrrhonian tale of flayed skin, which raises questions about the body, virtue, and belief, becomes increasingly polemical when read in the context of the Pauline tradition. As Pyrrho and Paul were almost certainly significant points of reference for both Shakespeare and Montaigne, this figure of flaying is a vehicle through which both authors, each in his own distinctive mode, propose a critique of fanaticism, a critique which may have originated in the roots of early Skepticism. Through the universal vulnerability of the skin, Montaigne and Shakespeare encourage us to consider alternative paths to tranquility through pacifism, self-preservation, and tolerance.
From Cartesian Ruins: Rocking Chair Phenomenology
Authors: Dennis Amanda M.
Published: May 2023

Chapter One compares both thinkers’ ambivalent engagement with Descartes: Beckett’s parody of Cartesian rationalism in Murphy and Merleau-Ponty’s revision of the cogito as he develops the ‘body-subject’. Both Merleau-Ponty and Beckett replace a transcendental subject with an embodied one, figured horrifically and comically (in Beckett) as part of its material world. This gesture is reprised in Beckett’s anti-anthropomorphic fable, ‘The End’ (1946), which is interpreted here as a coda to Murphy.
Short-Circuited Rationalism, or How the Body Means
Authors: Dennis Amanda M.
Published: May 2023

With reference to Merleau-Ponty’s essay ‘Cézanne’s Doubt’ (1945), Chapter Two shows how paradox in Beckett provokes the jarring of ‘incompossibles’, creating space in which objects become visible from multiple perspectives. In Beckett’s interwar novel Watt and in in Waiting for Godot (1948)—particularly Lucky’s monologue—language is revitalised by its connection to the sensing body. Intellection is revealed as bodily, passive as well as active, challenging assumptions that undergird humanist agency.
Introduction
Authors: Fallows Tom
Published: May 2023

By 1973, George A. Romero’s career as an independent film director appeared to be over. His debut feature Night of the Living Dead (1968) – a violent horror film made in Pittsburgh, PA – had generated $30 million worldwide1 on a budget of $114,000, yet the film’s success was difficult to emulate. ...
Last Stand: Mergers, Acquisitions and the Small Business Enterprise, 1985–1994
Authors: Fallows Tom
Published: May 2023

Chapter 5 looks at Laurel’s regeneration in the wake of Romero’s departure, giving special attention to the firm’s merger with television producer Aaron Spelling Productions in 1989. An inquiry into media industry mergers and acquisitions traditionally falls upon top-level machinations and the moguls, conglomerates and major players who dictate the fate of the industry at large. Analysis of a subjacent player like Laurel offers a ground-level perspective, providing a rare case study of one of the many small business enterprises swept up (or swept away) by these waves of consolidation. The chapter looks at the impact of the Spelling merger on output and corporate identity, detailing Laurel’s move into television and the production of ‘event’ programming such as the ABC miniseries The Stand. This is followed by an evaluation of the limits imposed by this merger, paying attention to the 1990s M&A wave and Viacom’s purchase of Spelling in 1994, a transaction that resulted in Laurel’s untimely demise.
Epilogue: Life After Death
Authors: Fallows Tom
Published: May 2023

In order to make sense of current media industry practices and future directions, Paul McDonald argues that researchers must ‘contextualise these contemporary phenomena, recognizing how the signs of continuity and change witnessed in the media industries of today arise from complex and contested histories’.1...
Gossip, Hearsay, and the Character Exception: Reputation on Trial in The Tenant of Wildfell Hall and R v Rowton
Authors: Frank Cathrine O.
Published: May 2023

When a defendant cannot or will not speak, as Hester Prynne and Hetty Sorrel do not, others must be relied on to provide the necessary character evidence. But what are the conditions and limits on the kinds of testimony a witness might give? Chapter Two examines legal objections to hearsay as compared to the novel’s more liberal treatment of gossip. One of the most routine exceptions to the rule against hearsay is the character exception, or the idea that testimony as to general reputation can be admitted as evidence. However, even legal commentators of the day, responding to a controversial decision in Regina v. Rowton (1864), lamented that the court’s rejection of a witness’s personal experience of the defendant—in favor of general reputation—reduced that testimony to little more than hearsay, or gossip. A reading of the legal decision is situated within discussion of Anne Bronte’s The Tenant of Wildfell Hall and Elizabeth Gaskell’s Cranford as novels which not only admit gossip but repurpose it for narratological and sociological goals of community building.
Defamation of Character: Anthony Trollope and the Law of Libel
Authors: Frank Cathrine O.
Published: May 2023

Chapter three considers how libel laws enabled character to go on the offensive during the rise of professional journalism. While novelists certainly capitalized on the public taste for scandal and its interest in famous trials when devising plots, surprisingly few seem to have taken up the issues of libel and slander explicitly. However, Anthony Trollope’s ongoing engagement with the press makes him a notable exception. Chapter three situates Trollope’s novels of the 1860s and ‘70s within significant developments in libel law. Beginning with the period of his editorship of St Paul’s Magazine and publication of Phineas Finn (1869) and Phineas Redux (1873), it argues that these years mark an historical junction of legal, literary, and journalistic concern with libel to which Trollope was particularly attentive because so many of his characters brought reputations with them from one novel to the next. Ending with The Prime Minister (1876), Cousin Henry (1879), and new legislation for enlarging freedom of the press, the chapter concludes that Trollope’s ethics of representation and method of literary characterization anticipated the limits of libel law and opened the way for what might be a more effective means of protecting character through privacy.
Dignity, Disclosure, and the Right to Privacy: The Strange Characters of Dr. Jekyll and Dorian Gray
Authors: Frank Cathrine O.
Published: May 2023

Chapter Four reads Stevenson’s and Wilde’s novels through the lens of Warren and Brandeis’s 1890 Harvard Law Review article “The Right to Privacy” and examines the ways in which each novel explores the idea of controlling one’s image by controlling the disclosure of or access to forms of intellectual and artistic property (the formula, the confession, the portrait) and with them the “personality” grounding privacy. Because ownership, no matter how broadly defined, continues as the foundation of inviolability, these novels raise questions about the integrity of the personality that could have such rights and under what conditions those rights become forfeit. Subjects of gossip on the one hand, on the other hand, both Dr. Jekyll and Dorian engage in acts of self-disclosure where the act emphasizes self-possession but the nature of the disclosure (or the failure to read it correctly) emphasizes an alienated self. Depicted through scenes of disarticulation and growing incoherence, Henry Jekyll and Dorian Gray thus provide a limit test of the premise of “inviolability” on which Warren and Brandeis build their privacy protection.
Poetic Donation from Homer to Kant
Authors: Rosenthal Adam R.
Published: May 2023

This chapter examines the complicity among figures of inspiration, talent, imagination, and genius, as tropes that all imply a divine or otherworldly givenness for the poetic work. It argues that from Homer up through Kant, the primary means of accounting for the existence of poetry was through a divine gift, or a gift of Nature. Thus, while each of these well-known tropes bears its own distinct history, they also testify to the importance of a general gift logic, for works of poetry. The ability for writing true poetry, in sum, is deemed to be unlearnable, and so only through innate or extraworldly gifts can the poetic work be accounted for.
Baudelaire and the Gift of Pleasing
Authors: Rosenthal Adam R.
Published: May 2023

This chapter looks at the interconnection of poetry and giving in the nineteenth-century French poet, Charles Baudelaire, by examining the prose poem ‘The Fairies’ Gifts.’ Published in the Flowers of Evil, ‘The Fairies’ Gifts’ offers a parable of poetry and explores the difficulty of separating aesthetic objects from economic ones. As with Emerson and Kant, for Baudelaire, the question as to the place of poetry comes down to the nature of the pleasure it offers. Similar to Thoreau, however, what ‘The Fairies’ Gifts’ ultimately shows is that the role of the poem is no longer to create a pure aesthetic pleasure removed from the interested exchange of the market, but rather, precisely, to trouble the difference between these two realms without, however, simply collapsing them.
Introduction: Text: The Difference between Philosophy and Literature
Authors: Dutton James
Published: May 2023

This introduction focuses on Proust’s refusal of the difference between philosophy and literature. It surveys notable readings of his Recherche by philosophers and critics and argues that in Proust’s challenge to the distinction between literature and philosophy we can note an affirmation of the elusiveness of genre, textual categories, and writing more generally—that any definition of writing reduces, or does violence to, reading. In this sense, Proust shows how writring is under incessant reformation, a process that places all texts under the same movement. Literary texts are constantly becoming-other than themselves, or what we may seek to define them “as”—such resistance to typology is their literary basis. This process of textual becoming is then identified as key to the philosophies of Deleuze and Derrida, and is used as a basis from which to observe the complex approaches to textuality proposed by all three thinkers.
Sense: The Hollow of Experience, the Mark[ ] of Aiôn
Authors: Dutton James
Published: May 2023

This chapter examines the picture of temporal experience provided by the novel considered in light of its rejection of presentational logic. It examines the novel’s opening scene to form an understanding of Deleuze’s theories of the virtual and dividual, and suggests that the setting-less, transversal beginning of the Recherche institutes the novel’s peculiarly multi-temporal quality. By incorporating Henri Bergson’s thoughts on nonnumerical multiplicity, as well as the theories of temporality and perception of Edmund Husserl, Maurice Merleau-Ponty and Mauro Carbone, this chapter situates its reading across a phenomenological tradition of transcendental sense, but claims that the immanent-real category of literary “remains” anchors this sense in living becoming. In doing so, it offers a reading that, while steeped in and engaging with a specific and critically recognized philosophical tradition, suggests a more “literary” understanding of its possibilities. By observing phenomenally attuned portrayals of experience like dreams and lying, Proust’s fiction directs us towards the depth and imperviousness of imaginative becoming, asking us how much of experience it is possible to forget—or if it is possible to forget at all.
PEMANFAATAN LAHAN DAN SUMBER AIR DI KAMPUNG WISATA CIWALUH
Authors: Hedi Heryadi  , Adhi Susilo  , Rinda Noviyanti  , Venty Fitriany Nurunisa
Published: May 2023

Keberhasilan usaha budidaya ikan sangat tergantung pada kualitas air yang digunakan. Desa Ciwaluh yang terletak di Desa Wates Jaya Kecamatan Cigombong Kabupaten Bogor memiliki sumber mata air yang tidak pernah kering. Dengan luas wilayah 15 hektar sawah dan 39 hektar daratan masyarakat Ciwaluh telah berhasil menjadikan desanya menjadi kampung wisata. Hal ini menjadikan optimisme bagi kami untuk menggerakkan mereka memanfaatkan lahan dan sumber airnya. Budidaya ikan yang saat ini sangat mudah untuk dilaksanakan dan banyak dilakukan oleh masyarakat luas adalah budidaya ikan dengan menggunakan kolam terpal. Kelebihan menggunakan kolam terpal antara lain: simpel, tidak harus melubangi tanah, dapat disusun dilahan sempit, dan biayanya lebih ekonomis. Kolam terpal yang diterapkan di desa Ciwaluh menggunakan bentuk lingkaran sebanyak 2 buah dengan diameter 3 m dan bentuk persegi berukuran 3x3 m2 sebanyak 1 buah dengan total jumlah ikan nila yang ditebar 500 ekor, serta ikan lele 3000 ekor. Ukuran ikan nila yang ditebar berkisar 9-10 ekor/kg, sedangkan ukuran ikan lele yang ditebar 15-16 ekor/kg.  Proses budidaya diawali dengan penyiapan lahan, persiapan kolam, persiapan benih ikan, pembuatan kolam terpal, penebaran benih ikan, manajemen pemberian pakan sampai dilakukan panen. Pemberian pakan dilakukan 2 kali sehari menggunakan pakan dengan kandungan protein 30-40%. Panen akan dilakukan apabila ikan nila berjumlah 4-5ekor untuk 1 kilogramnya sedangkan untuk ikan lele 6-8 ekor untuk 1 kilogramnya. Hasil panen ikan ini akan dijual kepada wisatawan yang datang ke kampung wisata Ciwaluh, namun apabila ikan hasil panen tersebut tidak terserap oleh wisatawan seluruhnya maka sisanya akan dijual ke penduduk sekitar kampung Ciwaluh.
INOVASI GALERI DAN PEMASARAN BERBASIS DIGITAL UNTUK PRODUK KAIN TENUN KHAS SUKU BADUY
Authors: Suhartono  , Mulyono  , Eli Yuliansari  , Hudri
Published: May 2023

Tenun Baduy adalah warisan nenek moyang suku Baduy. Awalnya bahan tenun terbuat dari kulit kayu, konon waktu itu kapas sangat sulit di dapat. Kain yang terbuat dari kulit kayu disebut Samping Popok. Seiring berjalannya waktu tenun mulai diproduksi dengan bahan yang terbuat dari benang berwarna putih. Pada tahun 1990 Tenun Baduy mulai di kenal masyarakat luas sehingga banyak wisatawan yang berdatangan untuk mengenal lebih dekat. Terdapat 20 nama motif kain tenun Baduy, salah satunya adalah suat songket, adumancung, dan susuatan. Tenun baduy identik dengan kaum perempuan, bagi perempuan suku Baduy luar, menenun menjadi tolak ukur kesabaran kepribadian. Menenun membutuhkan kesabaran yang luar biasa. Satu helai kain tenun Baduy ukuran 100x200cm, membutuhkan waktu pembuatan hingga tiga minggu. Dengan harga jual Rp. 300.000-350.000 perhelai kain tenun, tentu ini bukan pendapatan yang seimbang, jika dibandingkan dengan lama pembuatannya, tetapi bagi mereka keahlian lebih mahal dari nilai rupiah. Melalui program pemberdayaan penenun di lingkungan suku Baduy luar, pada tahun 2022 dilaksanakan program pendampingan dan bantuan modal usaha melalui program wirausaha muda mandiri LPPM-UT. Kegiatan ini bertujuan menghasilkan kain tenun yang memiliki nilai ekonomi lebih baik tanpa mengurangi kualitasnya. Dengan melibatkan para mahasiswa Universitas Terbuka yang berdomisili sekitar Baduy berupaya mengembangkan inovasi galeri dan mengemas pemasaran berbasis digital pada produk tenun. Kegiatan ini berlangsung selama delapan bulan dengan menghasilkan kain tenun berbagai macam ukuran dan motif serta memadukan bahan tenun menjadi bentuk fashion kekinian.
PEMBERDAYAAN MASYARAKAT MELALUI TEKNIK PRODUKSI USAHA MENJAHIT JENIS-JENIS HIJAB MODERN ANGGOTA PKK KEL. LAIKANG KEC. BIRINGKANAYA MAKASSAR
Authors: Kartini
Published: May 2023

Kehidupan masyarakat Kelurahan Laikang, Kecamatan Biringkanaya Makassar sebagian besar ekonominya menengah kebawah,  dan  kurangnya perhatian pemerintah  terhadap kesejahteraan masyarakat, sehingga pendidikan, pengetahuan, dan keterampilan bagi kelompok mayarakat kreatif berdampak pada minimnya inovasi para mayarakat  terhadap peningkatan kesejahteraan hidup, khususnya dalam hal pemanfaatan peningkatan nilai jual hasil produktivitas yang telah dihasilkan. Untuk itu, perlu diberikan suatu kegiatan berupa keterampilan yang dapat dijadikan sumber pendapatan untuk mengubah hidupnya menjadi lebih sejahtera. Oleh karena itu,  kami dari tim pengabdian kepada masyarakat  dosen UPBJJ-Universitas Terbuka Makassar  memberikan keterampian kepada kelompok PKK Kelurahan Laikang  Kec. Biringkanaya Makassar suatu usaha kreatif  Menjahit Jenis-Jenis Hijab modern  dan mukena ”Pelatihan  ini diikuti  21 orang dari anggota kelompok PKK Kelurahan Laikang Kec. Biringkanaya Makassar dan dilengkapi pasilitas berupa mesin jahit, ATK, Kain  untuk pembuatan hijab modern dan  perlengkapan jahit menjahit lainnya. Setelah selesai kegiatan praktek menjahit hijab  Anggota PKK Kel. Laikang  Kec. Biringkanaya Makassar  menunjukkan bahwa semua peserta dari 21 orang sudah terampil menjahit dan masing-masing berhasil menyelesaikan  satu lembar hijab dan mukena dengan rapi pada akhir pelaksanaan pelatihan. Presentasi capaian sebesar > 80%
EDUKASI KEWIRAUSAHAAN DAN EKONOMI KREATIF PADA KELOMPOK IBU RUMAH TANGGA DI KLENDER JAKARTA TIMUR
Authors: Ni Made Ayu Krisna Cahyadi  , Dian Sugiarti  , Suci Rahmawati Prima  , Rahmad Purnama  , Suhartono
Published: May 2023

Pandemi yang telah terjadi kurang lebih 2,5 tahun berdampak terhadap pendapatan masyarakat, utamanya dirasakan oleh ibu rumah tangga yang tidak memiliki tambahan pendapatan. Para ibu rumah tangga merasa kesulitan dalam memulai usaha maupun pengembangan usaha. Edukasi kewirausahaan yang bertujuan untuk meningkatkan motivasi wirausaha ini harapannya akan berdampak jangka panjang terhadap kelompok ibu rumah tangga di Kelurahan Klender, Jakarta Timur. Dampak jangka panjang merupakan target pencapaian kegiatan ini mengingat pandemi saat ini menunjukkan tren yang mulai menurun. Selain untuk meningkatkan motivasi, kegiatan ini juga bertujuan untuk mengedukasi kelompok ibu rumah tangga mengenai ekonomi kreatif. Paparan diisi oleh dua mompreneur yang telah sukses menerapkan ekonomi kreatif dalam usahanya dan dihadiri oleh 50 peserta yang merupakan kelompok ibu rumah tangga di Kelurahan Klender. Metode yang digunakan untuk mengukur tingkat keberhasilan kegiatan ini adalah dengan menggunakan pre-test dan post-test. Berdasarkan hasil tersebut, motivasi peserta untuk memulai usaha rata-rata meningkat sebesar 64,96%. Sementara pemahaman peserta mengenai ekonomi kreatif meningkat sebesar 70,25%.
UMKM KUAT: UPAYA MEWUJUDKAN UMKM MAJU DAN “NAIK KELAS”
Authors: Yusuf  , Christianingrum
Published: May 2023

Masalah terbesar yang banyak dihadapi oleh UMKM di Desa Air Ruai yaitu kurangnya pengetahuan dalam memasarkan baik secara konvensional (offline) terlebih secara online, khususnya e-commerce. Minimnya pengetahuan mengenai konsep digital marketing menginspirasi tim pengabdian untuk menyampaikan sosialisasi dan memberikan pelatihan digital marketing mengenai pemanfaatan teknologi informasi dan komunikasi. Kegiatan PkM telah dilaksanakan kepada 30 pelaku UMKM di Desa Air Ruai, Kecamatan Pemali Kabupaten Bangka. Berdasarkan permasalahan terbesarnya yaitu kurangnya informasi manajemen pemasaran maka solusi yang ditawarkan kepada mitra ialah dengan memberikan materi terkait dengan ragam penjualan, digital marketing, fotografi dan terakhir bagaimana membuat copy writing yang menarik. Metode yang digunakan dalam kegiatan ini adalah ceramah, diskusi, dan simulasi/ praktek. Luaran program ini yaitu 30 peserta berhasil memperkenalkan dan menjual produk dengan menerapkan strategi digital marketing melalui media online melalui penerapan  fitur fotografi serta copy writing pada stategi penjualan.
Establishing plausibility of cardiovascular adverse effects of immunotherapies using Mendelian randomisation
Authors: Le Nhu Ngoc , Tran Tran Quoc Bao , du Toit Clea , Gill Dipender , Padmanabhan Sandosh
Published: May 2023

Immune checkpoint inhibitors (ICIs) and Janus kinase inhibitors (JAKis) have raised concerns over serious unexpected cardiovascular adverse events. The widespread pleiotropy in genome-wide association studies offers an opportunity to identify cardiovascular risks from in-development drugs to help inform appropriate trial design and pharmacovigilance strategies. This study uses the Mendelian randomization (MR) approach to study the causal effects of 9 cardiovascular risk factors on ischemic stroke risk both independently and by mediation, followed by an interrogation of the implicated expression quantitative trait loci (eQTLs) to determine if the enriched pathways can explain the adverse stroke events observed with ICI or JAKi treatment. Genetic predisposition to higher systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), waist-to-hip ratio (WHR), low-density lipoprotein cholesterol (LDL), triglycerides (TG), type 2 diabetes (T2DM), and smoking index were associated with higher ischemic stroke risk. The associations of genetically predicted BMI, WHR, and TG on the outcome were attenuated after adjusting for genetically predicted T2DM [BMI: 53.15% mediated, 95% CI 17.21%–89.10%; WHR: 42.92% (4.17%–81.67%); TG: 72.05% (10.63%–133.46%)]. JAKis, programmed cell death protein 1 and programmed death ligand 1 inhibitors were implicated in the pathways enriched by the genes related to the instruments for each of SBP, DBP, WHR, T2DM, and LDL. Overall, MR mediation analyses support the role of T2DM in mediating the effects of BMI, WHR, and TG on ischemic stroke risk and follow-up pathway enrichment analysis highlights the utility of this approach in the early identification of potential harm from drugs.
Influence of solar forcing on multidecadal variability in the Atlantic meridional overturning circulation (AMOC)
Authors: Ye Aihua , Zhu Zhipeng , Zhang Ruyi , Xiao Ziniu , Zhou Limin
Published: May 2023

There is a growing debate regarding the influence of solar activity on climate change as the solar forcing signal on decadal/multidecadal timescales is not robust in long-term reconstructed climate data or numerical simulations. However, solar forcing could be amplified by ocean–atmosphere coupling in sensitive regions, including the North Atlantic Ocean (N.A.). This study assessed the influence of varied total solar irradiance (TSI) due to the effects of solar activity on Atlantic Meridional Overturning Circulation (AMOC) based on an Earth System model with intermediate complexity (PLASIM-GENIE). Three groups of experiments with different TSI series; i.e., constant (NS), decadal varied (DS), and reconstructed whole (AS) for 1610–2000, were conducted and the AMOC response was investigated. The results showed that the internal forcing of the climate system led to quasi-35-year and quasi-65-year AMOC cycles and a significant and stable negative correlation between TSI and AMOC on a multidecadal timescale. The period was significantly extended due to solar forcing. The declining AMOC trend occurred in simulations after 1800. Thus, solar forcing contributed to a weakening AMOC at a rate of 0.41 Sv per century. The decadal variation in TSI was the main contributor to this decline due to solar forcing.
Optimizing the distribution pattern of species under climate change: the protection and management of Phellodendron amurense in China
Authors: Zhang Boyan , Zou Hui , Chen Bingrui , Zhang Xiyuan , Kang Xun , Wang Chen , Zhang Xinxin
Published: May 2023

Objective

Phellodendron amurense, a special species in Northeast Asia, is the source of the wild medicinal Phellodendri Amurensis Cortex, the second-level key protection in China. Because of its dual value of medicine and timber, it has been cut in large quantities, resulting in a sharp decline in wild resources. It has been listed as a national first-class rare tree species. Here, we aim to plan protection area and wild tending area for Chinese P. amurense in the context of climate change.

Method

In this study, based on the Biomod2 model, the main environmental factors affecting the distribution and the potentially suitable areas of the current and future were investigated. Furthermore, the correlation between the main environmental factors and the chemical components was determined by full subset regression. Habitat quality and landscape pattern change were determined by InVEST and Fragstats software based on the land use data in 1980, 2000, and 2020. Then, Zonation software was used to plan the priority protection and wild tending areas.

Results

The results showed that in the future, the potential habitat of P. amurense will gradually move to the high latitude and high altitude areas in the northwest direction, and the high suitability area will decrease sharply. Since 1980, the habitat quality of P. amurense habitat has gradually deteriorated, and the fragmentation has gradually intensified. In the future, the central part of the Greater Khingan Mountains and the forest area of the Lesser Khingan Mountains will be the long-term stable sanctuary. Fengcheng City and Tonghua County are the most suitable for the wild tending areas.

Conclusion

The existing nature reserve only contains 6.01% of the priority protection area, so we propose to expand the area to cover a larger proportion of the sanctuary and implement management and restoration plans to increase the suitability and connectivity. These results can support the protection action and provide a reference and scientific basis for further research, rational development, and utilization of P. amurense.
Cognitive disorder and associated factors among pregnant women attending antenatal service at Dilla University Referral Hospital, 2022
Authors: Kassaw Chalachew , Wale Tiruwork , Negash Misrak , Temesgen Kiber , Mekuriaw Birhanie , Tolessa Omega , Abdisa Elias Nigusu , Chekol Yigrem Ali , Ayano Getinet , Anbesaw Tamrat
Published: May 2023

Introduction

Cognition is defined as the mental activity or process of learning information and understanding through reason, experience, and the senses. In Sub-Saharan African nations like Ethiopia, such assessments of a pregnant mother's mental health during antenatal care are uncommon procedures. Instead, there is a greater focus on the physical well-being of the woman and her fetus. As a result, this study aimed to evaluate the cognitive deficits and related factors in a pregnant women attending an antenatal care service.

Methods

This hospital-based cross-sectional study included 415 pregnant women who were receiving antenatal care at Dilla University Referral Hospital in Dilla, Gedeo Zone, Ethiopia. In this study, respondents were chosen using systematic random sampling, and study participants were interviewed using administered questions to gather pertinent data. This study used the OSLO Social Support Scale, the Alcohol, Smoking, and Substance Involvement Screening Test, and the Mini-Mental Status Examination to assess the social support, cognitive status, and current substance use history of a respondent. Descriptive statistics including frequencies, graphs, and percentages were used to describe the results. A logistic regression analysis was conducted to determine the connection between independent factors and the outcome variable at a 95 percent confidence level and p < 0.05.

Result

Among all respondents who came for antenatal care visits, only 24 (5.8%) were unmarried (single, divorced, widowed). The mean age of respondents was 26 years old and 155 (37.3%) had attended secondary school. Variables such as strong social support [0.11 (0.03–0.23), p < 0.02], being a follower of orthodox religion [0.24 (0.12–0.39), p < 0.04], ≥5,000 Ethiopian birr monthly income [0.28 (0.17–0.48), p < 0.02], age >26 years old [1.23 (1.14–2.54), p < 0.04], unplanned pregnancy [2.78 (1.45–4.32), p < 0.02], and rural residence [3.90 (2.23–7.34), p < 0.04] were significantly associated with cognitive impairment at 95% confidence interval and a p-value <0.05.

Conclusion

This study found that pregnant women who attended antenatal care experienced a significant reduction in cognitive disorders. Additionally, this study revealed adjustable factors such as unwanted pregnancy, social support, and religiosity. It is preferable to check a pregnant woman's cognitive condition at antenatal services and to follow-up on each additional visit.
Effects of multiple pro-inflammatory stimuli in utero on the ileum of extremely premature ovine fetuses
Authors: Heiter Julia , Kemp Matthew W. , Spiller Owen B. , Singer Dominique , Newnham John P. , Kallapur Suhas G. , Jobe Alan H. , Kramer Boris W.
Published: May 2023

Introduction

Chorioamnionitis is common in preterm birth and associated with a higher risk of intestinal inflammation and necrotizing enterocolitis. The intestinal inflammation influences the enteric nervous system development. We hypothesized that inflammation and innervation in the fetal ileum may be modified by chorioamnionitis induced by repeated challenge with lipopolysaccharide and/or preexisting Ureaplasma parvum infection at very low gestational age equivalent to 60% of term.

Materials and methods

Time mated ovine fetuses were exposed by intraamniotic injections to chronic Ureaplasma parvum for 24 days and/or lipopolysaccharide for 7 days, 2 days, or 7 & 2 days before delivery at 94 +/-2 days of gestational age (term at approximately 150 days). Intestinal inflammation as well as structural changes of the enteric nervous system were assessed.

Results

Lipopolysaccharide exposure increased CD3 and myeloperoxidase-positive cells (p < 0.05). Repetitive exposure to lipopolysaccharide or combined Ureaplasma parvum & lipopolysaccharide exposure increased intestinal inflammation (p < 0.05). The reduction of nuclei of neurons was most significant with repetitive lipopolysaccharide exposures but could be detected in all other intervention groups compared to the control group. Astrocyte-like glial cells increased if exposure to lipopolysaccharide was only 2 days before delivery or chronic exposure to Ureaplasma parvum existed beforehand (p < 0.05).

Discussion

After exposure to chorioamnionitis induced by Ureaplasma parvum and/or lipopolysaccharide, inflammatory responses as well as structural changes of the enteric nervous system were more pronounced the longer and the more frequent the exposure to pro-inflammatory stimuli before birth. These changes may cause functional effects of clinical importance.
The human Stat1 gain-of-function T385M mutation causes expansion of activated T-follicular helper/T-helper 1-like CD4 T cells and sex-biased autoimmunity in specific pathogen-free mice
Authors: Scott Ori , Visuvanathan Shagana , Reddy Emily , Mahamed Deeqa , Gu Bin , Roifman Chaim M. , Cohn Ronald D. , Guidos Cynthia J. , Ivakine Evgueni A.
Published: May 2023

Introduction

Humans with gain-of-function (GOF) mutations in STAT1 (Signal Transducer and Activator of Transcription 1), a potent immune regulator, experience frequent infections. About one-third, especially those with DNA-binding domain (DBD) mutations such as T385M, also develop autoimmunity, sometimes accompanied by increases in T-helper 1 (Th1) and T-follicular helper (Tfh) CD4 effector T cells, resembling those that differentiate following infection-induced STAT1 signaling. However, environmental and molecular mechanisms contributing to autoimmunity in STAT1 GOF patients are not defined.

Methods

We generated Stat1T385M/+ mutant mice to model the immune impacts of STAT1 DBD GOF under specific-pathogen free (SPF) conditions.

Results

Stat1T385M/+ lymphocytes had more total Stat1 at baseline and also higher amounts of IFNg-induced pStat1. Young mutants exhibited expansion of Tfh-like cells, while older mutants developed autoimmunity accompanied by increased Tfh-like cells, B cell activation and germinal center (GC) formation. Mutant females exhibited these immune changes sooner and more robustly than males, identifying significant sex effects of Stat1T385M-induced immune dysregulation. Single cell RNA-Seq (scRNA-Seq) analysis revealed that Stat1T385M activated transcription of GC-associated programs in both B and T cells. However, it had the strongest transcriptional impact on T cells, promoting aberrant CD4 T cell activation and imparting both Tfh-like and Th1-like effector programs.

Discussion

Collectively, these data demonstrate that in the absence of overt infection, Stat1T385M disrupted naïve CD4 T cell homeostasis and promoted expansion and differentiation of abnormal Tfh/Th1-like helper and GC-like B cells, eventually leading to sex-biased autoimmunity, suggesting a model for STAT1 GOF-induced immune dysregulation and autoimmune sequelae in humans.
Reviewing the knowledge on the genus Patella in the Mediterranean Sea: testing the effect of protection on the mean abundance and size of Patella ferruginea
Authors: Cascales-Soler Ana , Ramos-Espla Alfonso Angel , Forcada Aitor
Published: May 2023

Increasing human pressure has strongly impacted the littoral environment, altering the habitats and population parameters of some species. The Mediterranean Sea is one of the regions that have been highly affected by these events. In response to these events, marine protected areas (MPAs) have emerged as one of the main conservation tools for marine habitats and species. In this regard, harvesting of limpets (Patella spp.) is a good example of the impact of human activity on the coast. Limpets are mollusks that are collected as food or fishing bait, and their exploitation causes an immediate decrease in the density and size structure of individuals. In the Mediterranean Sea, the genus Patella is represented by five species: Patella rustica, P. caerulea, P. ulyssiponensis, P. ferruginea, and P. depressa. To verify the effectiveness of the MPAs, a deep review of 75 studies on Patella spp. in the Mediterranean Sea was conducted to analyze the spatial and temporal distribution of studies. Data extracted from these articles were used to assess the effect of protection on the density and size of P. ferruginea. Regarding spatial distribution, the studies reviewed were performed at 67 sites in 13 countries, of which 23 were in MPAs and 44 in non-protected or control areas. The findings of this study show that P. ferruginea is the species most studied, because it is one of the most threatened marine invertebrates in the Mediterranean Sea. This explains the temporal distribution of the studies, which coincides with the establishment of the conservation status and the concern about the population status of P. ferruginea. Analysis of the effect of protection on the density and mean size of P. ferruginea individuals revealed no significant difference in mean density between the control sites and MPAs. However, mean size between individuals was significantly higher in MPAs than control sites. This pattern may be related to intra- and interspecific competition between individuals.
Ultrasound assessment of the respiratory system using diaphragm motion-volume indices
Authors: Boussuges Alain , Chaumet Guillaume , Boussuges Martin , Menard Amelie , Delliaux Stephane , Brégeon Fabienne
Published: May 2023

Background

Although previous studies have determined limit values of normality for diaphragm excursion and thickening, it would be beneficial to determine the normal diaphragm motion-to-inspired volume ratio that integrates the activity of the diaphragm and the quality of the respiratory system.

Methods

To determine the normal values of selected ultrasound diaphragm motion-volume indices, subjects with normal pulmonary function testing were recruited. Ultrasound examination recorded diaphragm excursion on both sides during quiet breathing and deep inspiration. Diaphragm thickness was also measured. The inspired volumes of the corresponding cycles were systematically recorded using a spirometer. The indices were calculated using the ratio excursion, or percentage of thickening, divided by the corresponding breathing volume. From this corhort, normal values and limit values for normality were determined. These measurements were compared to those performed on the healthy side in patients with hemidiaphragm paralysis because an increase in hemidiaphragm activity has been previously demonstated in such circumstances.

Results

A total of 122 subjects (51 women, 71 men) with normal pulmonary function were included in the study. Statistical analysis revealed that the ratio of excursion, or percentage of thickening, to inspired volume ratio significantly differed between males and females. When the above-mentioned indices using excursion were normalized by body weight, no gender differences were found. The indices differed between normal respiratory function subjects and patients with hemidiaphragm paralysis (27 women, 41 men). On the paralyzed side, the average ratio of the excursion divided by the inspired volume was zero. On the healthy side, the indices using the excursion and the percentage of thickening during quiet breathing or deep inspiration were significantly increased comparedto patients with normal lung function. According to the logistic regression analysis, the most relevant indice appeared to be the ratio of the excursion measured during quiet breathing to the inspired volume.

Conclusion

The normal values of the diaphragm motion-volume indices could be useful to estimate the performance of the respiratory system. Proposed indices appear suitable in a context of hyperactivity.