bluuebunny/crossref_metadata_2025 huggingface dataset:
Binary Hydrogels: Induction Methods and Recent Application Progress as Food Matrices for Bioactive Compounds Delivery—A Bibliometric Review
Authors: Hilal Adonis , Florowska Anna , Wroniak Małgorzata
Published: January 2023

Food hydrogels are biopolymeric materials made from food-grade biopolymers with gelling properties (proteins and polysaccharides) and a 3D network capable of incorporating large amounts of water. They have sparked considerable interest because of their potential and broad application range in the biomedical and pharmaceutical sectors. However, hydrogel research in the field of food science is still limited. This knowledge gap provides numerous opportunities for implementing their unique properties, such as high water-holding capacity, moderated texture, compatibility with other substances, cell biocompatibility, biodegradability, and high resemblance to living tissues, for the development of novel, functional food matrices. For that reason, this article includes a bibliometric analysis characterizing research trends in food protein–polysaccharide hydrogels (over the last ten years). Additionally, it characterizes the most recent developments in hydrogel induction methods and the most recent application progress of hydrogels as food matrices as carriers for the targeted delivery of bioactive compounds. Finally, this article provides a future perspective on the need to evaluate the feasibility of using plant-based proteins and polysaccharides to develop food matrices that protect nutrients, including bioactive substances, throughout processing, storage, and digestion until they reach the specific targeted area of the digestive system.
Ageism and the Pandemic: Risk and Protective Factors of Well-Being in Older People
Authors: Donizzetti Anna Rosa , Capone Vincenza
Published: January 2023

The COVID-19 pandemic has particularly affected the older population both in terms of the high number of victims and the psychological impact. Moreover, the pandemic has made older people more vulnerable to isolation and loneliness, and victims of ageism. The aim of the present study was to investigate the risk and protective factors for the well-being of older people during the pandemic. The role of positive affect, confidence in the future, current physical health, social isolation, loneliness, and ageism were analysed. A self-report questionnaire was administered to 1301 participants (mean age: 77.3 years, DS: 5.46), almost equally distributed by gender (56.1% female). Descriptive and correlational analyses were performed, together with SEM. The results showed that perceived age discrimination positively predicts loneliness and negatively and indirectly predicts well-being. Furthermore, positive affect, confidence in the future, and current physical health are protective factors, while loneliness, social isolation, and ageism are risk factors. Future emergency policies must take into account the impact of such actions on the well-being of this segment of the population.
‘A Whole Other World than What I Live in’: Reading Chester Himes, on Campus and at the County Jail
Authors: Wiltse Ed
Published: January 2023

This essay first briefly examines African American novelist Chester Himes’ genre-defying position as prison writer turned detective writer, whose influence is clear not only in the usual suspects such as Walter Mosley but also in the Blaxploitation films of the early 1970s, and in the urban fiction tradition from Donald Goines and Iceberg Slim on down through today’s Triple Crown books and others. I then look at how Himes’ work has been received by the college students and incarcerated people who each spring for the past 20 years have worked together in reading groups set at the local county jail in a project linked to a class I teach, in order to raise questions about genre, audience and pedagogy. The two groups of readers, who may come to see each other as one group over the series of meetings, often develop readings of Himes’ novel that push back against the analysis I present in the classroom.
Human, All Too Human: Differentiating Non-Human from Human Bones in Protohistoric Cremation Contexts from Northern Italy
Authors: Larentis Omar
Published: January 2023

Differentiating cremated non-human bones from human ones in archaeological contexts is a challenging task. This analysis aims at proposing a rather solid criterion based on an osteoarchaeological sample. In this work, the main issues of taxonomic identification of cremated remains are analysed and a research methodology tested on an Italian protohistoric sample is proposed. The 314 subjects composing the sample come from 298 tombs of the Golasecca Civilization (1st millennium BC in north-eastern Italy). On a morphological basis, 246 bone fragments were selected from which as many thin sections were obtained for a histomorphological evaluation. From the analyses, we identified the presence of animals in burials, whereas a mere morphometric analysis was not able to recognize them. Furthermore, the taxonomic identification has allowed us to propose new hypotheses on the funerary rite of Golasecca linked to the zooarchaeological remains.
Once upon a Glass—Cycles, Recycles and Reuses of a Never-Ending Material
Authors: Chinni Tania , Silvestri Alberta , Fiorentino Sara , Vandini Mariangela
Published: January 2023

Glass can be considered a locus of meaning, a material which has been the repository of traditional knowledge and technological expertise for at least three millennia. The history of glass speaks of know-how, technological transitions, and contaminations of recipes for its manufacture, which have changed across the world over the centuries. As the amount of recovered glass from archaeological contexts is much lower compared to ceramic and metal finds, research has often considered glass as a rare material. Furthermore, glass production, in ancient times as in the present day, requires the use of selected raw materials and noticeable amounts of fuel, making reuse and recycling practices necessary to foster sustainability, from both an economical and an environmental perspective. Latin authors, such as Juvenal and Martial, reported buyers of broken glass in Imperial Rome, presumably destined for recycling. Archaeometry has also provided data that allow, today, to clarify different aspects related to production cycles, uses and reuses of a material that, starting from the Roman age, became as common as modern plastics. From beakers and goblets reused with different purposes to mosaic tesserae detached for making new mosaics or to be refused and employed as “pigments” for colouring glass, this paper aims to provide an overview of reuse and recycling practices of ancient glass through a discussion of selected case studies from Roman to Middle Ages, showing how the cycle of this material can be framed as an actual example of sustainable circular economy in the past.
Thermochromicity in Wool Dyed with 6-Bromoindigo Depends on the Presence and Identity of a Solvent
Authors: Ramig Keith , Eskaros Timone , Islam Tazrian , Lavinda Olga , Karimi Sasan , Massa Lou , Cooksey Christopher
Published: January 2023

The thermochromic effect of wool dyed with 6-bromoindigo was found to depend on both heat and a solvent. The dyed fabric must be immersed in a solvent while heating for a color change from purple to blue to occur. Ethanol was the most effective solvent in causing the color change. Water was effective as well. 1-Butanol caused a slight color change, while toluene was completely ineffective. These results are interpreted as interaction of the solvent with both the wool surface and adsorbed dye molecular aggregates, causing changes in the size of large red aggregates to smaller blue ones. The mildest conditions for the color change, immersion in water at 60 °C, are so easily obtained that it is possible that ancient dyers knew of this as a finishing process for their dyeing, or knew to avoid post-dyeing heat treatment.
The Boundary between Two Modes of Gas Evolution: Oscillatory (H2 and O2) and Conventional Redox (O2 Only), in the Hydrocarbon/H2O2/Cu(II)/CH3CN System
Authors: Shchapin Igor Yu. , Nekhaev Andrey I.
Published: January 2023

During the oxidation of hydrocarbons using hydrogen peroxide solutions, the evolution of gaseous oxygen is a side and undesirable process, in which the consumption of the oxidizer is not associated with the formation of target products. Therefore, no attention is paid to the systematic study of the chemical composition of the gas and the mechanisms of its formation. Filling this gap, the authors discovered a number of new, previously unidentified, interesting facts concerning both gas evolution and the oxidation of hydrocarbons. In a 33% H2O2/Cu2Cl4·2DMG/CH3CN system, where DMG is dimethylglyoxime (Butane-2,3-dione dioxime), and is at 50 °C, evidence of significant evolution of gaseous hydrogen, along with the evolution of gaseous oxygen was found. In the authors’ opinion, which requires additional verification, the ratio of gaseous hydrogen and oxygen in the discussed catalytic system can reach up to 1:1. The conditions in which only gaseous oxygen is formed are selected. Using a number of oxidizable hydrocarbons with the first adiabatic ionization potentials (AIPs) of a wide range of values, it was found that the first stage of such a process of evolving only gaseous oxygen was the single electron transfer from hydrogen peroxide molecules to trinuclear copper clusters with the formation, respectively, of hydrogen peroxide radical cations H2O2•+ and radical anions Cu3Cl5•− (AIP = 5 eV). When the conditions for the implementation of such a single electron transfer mechanism are exhausted, the channel of decomposition of hydrogen peroxide molecules into gaseous hydrogen and oxygen is switched on, which is accompanied by the transition of the system to an oscillatory mode of gas evolution. In some cases, the formation of additional amounts of gaseous products is provided by the catalytically activated decomposition of water molecules into hydrogen and oxygen after the complete consumption of hydrogen peroxide molecules in the reaction of gaseous oxygen evolution. The adiabatic electron affinity of various forms of copper molecules involved in chemical processes is calculated by the density functional theory method.
Assessment of a Smartphone App for Open Channel Flow Measurement in Data Scarce Irrigation Schemes
Authors: Damtie Menwagaw T. , Jumber Marshet B. , Zimale Fasikaw A. , Tilahun Seifu A.
Published: January 2023

Accurate water flow measurement ensures proper irrigation water management by allocating the desired amount of water to the irrigation fields. The present study evaluated whether the non-intrusive smartphone application “DischargeApp” could be applicable and precise to measure small canal flow rates in the Koga irrigation Scheme. The app was tested in unlined canals with flow rates ranging from 15 to 65 l/s using a 90° V-notch weir. The app is found to overestimate high flow rates. Another source of uncertainty is that the app employed a constant surface velocity conversion factor (C = 0.8) to compute discharge. The accuracy was enhanced by recalculating the measured discharge using a new surface velocity conversion factor that depends on depths. The new conversion factor decreased the errors of MAE and RMSE by 47% and 52%, respectively. Where channel and other optional measuring techniques are not available without interfering with the flow operation conditions in place, the DischargeApp devices can be used to measure flows. The DischargeApp could be used to collect data using local citizens in data-scarce areas. This study suggested reconfiguring the DischargeApp with a new surface velocity conversion coefficient based on flow depths in field conditions for better performance.
Males’ Lived Experience with Self-Perceived Pornography Addiction: A Qualitative Study of Problematic Porn Use
Authors: Hanseder Sophia , Dantas Jaya A. R.
Published: January 2023

The positive impact of pornography use has been demonstrated; however, most research points towards problematic, compulsive, or excessive engagement with pornography and associated adverse effects on well-being. However, results remain inconclusive and qualitative research capturing perspectives of affected people is scarce. This phenomenological study aimed to explore the perspective and lived experience of males with a self-reported addiction to pornography. Semi-structured in-depth interviews with 13 males aged between 21 and 66 years from Australia and the USA were conducted. A thematic analysis of the transcripts was undertaken, resulting in the identification of four themes. The interviews explored the participants’ reasoning for determining themselves as porn addicts, investigated patterns of use, examined the perceived multifaceted impacts of pornography use, illustrated applied individual strategies to overcome the addiction, and proposed interventions helping to inform future recommendations. Experiences and perceptions of pornography addiction were consistently depicted as problematic and harmful. Most participants described an inability to stop their consumption despite experiencing adverse effects. Commonly reported was a gradual increase in the use of and consumption of new or more shocking content. Consumption of content was outlined as an escape or coping mechanism for negative emotions or boredom. Participants reported a variety of applied strategies to manage their addiction and suggested recommendations. Investigation into strategies for the identification of problematic pornography use, its conceptualization, associated health outcomes, and effective preventative and interventional strategies are required to provide academic consistency, support those negatively affected by pornography, and achieve increased public awareness of the issue.
Musculoskeletal-Modeling-Based, Full-Body Load-Assessment Tool for Ergonomists (MATE): Method Development and Proof of Concept Case Studies
Authors: van der Have Arthur , Van Rossom Sam , Jonkers Ilse
Published: January 2023

A new ergonomic-risk-assessment tool was developed that combines musculoskeletal-model-based loading estimates with insights from fatigue failure theory to evaluate full-body musculoskeletal loading during dynamic tasks. Musculoskeletal-modeling output parameters, i.e., joint contact forces and muscle forces, were combined with tissue-specific injury thresholds that account for loading frequency to determine the injury risk for muscles, lower back, and hip cartilage. The potential of this new risk-assessment tool is demonstrated for defining ergonomic interventions in terms of lifting characteristics, back and shoulder exoskeleton assistance, box transferring, stoop lifting, and an overhead wiring task, respectively. The MATE identifies the risk of WMSDs in different anatomical regions during occupational tasks and allows for the evaluation of the impact of interventions that modify specific lifting characteristics, i.e., load weight versus task repetition. Furthermore, and in clear contrast to currently available ergonomic assessment scores, the effects of the exoskeleton assistance level on the risk of WMSDs of full-body musculoskeletal loading (in particular, the muscles, lower back, and hips) can be evaluated and shows small reductions in musculoskeletal loading but not in injury risk. Therefore, the MATE is a risk-assessment tool based on a full-body, musculoskeletal-modeling approach combined with insights from the fatigue failure theory that shows the proof of concept of a shoulder and back exoskeleton. Furthermore, it accounts for subject-specific characteristics (age and BMI), further enhancing individualized ergonomic-risk assessment.
Application of Natural Language Processing (NLP) in Detecting and Preventing Suicide Ideation: A Systematic Review
Authors: Arowosegbe Abayomi , Oyelade Tope
Published: January 2023

(1) Introduction: Around a million people are reported to die by suicide every year, and due to the stigma associated with the nature of the death, this figure is usually assumed to be an underestimate. Machine learning and artificial intelligence such as natural language processing has the potential to become a major technique for the detection, diagnosis, and treatment of people. (2) Methods: PubMed, EMBASE, MEDLINE, PsycInfo, and Global Health databases were searched for studies that reported use of NLP for suicide ideation or self-harm. (3) Result: The preliminary search of 5 databases generated 387 results. Removal of duplicates resulted in 158 potentially suitable studies. Twenty papers were finally included in this review. (4) Discussion: Studies show that combining structured and unstructured data in NLP data modelling yielded more accurate results than utilizing either alone. Additionally, to reduce suicides, people with mental problems must be continuously and passively monitored. (5) Conclusions: The use of AI&ML opens new avenues for considerably guiding risk prediction and advancing suicide prevention frameworks. The review’s analysis of the included research revealed that the use of NLP may result in low-cost and effective alternatives to existing resource-intensive methods of suicide prevention.
Chemical Weathering and CO2 Consumption Inferred from Riverine Water Chemistry in the Xi River Drainage, South China
Authors: Zhao Yanpu , Wijbrans Jan R. , Wang Hua , Vroon Pieter Z. , Ma Jianghao , Zhao Yanqiong
Published: January 2023

Hydrochemistry and strontium isotope data were analysed in water samples from the Xi River Drainage system to reveal the spatial and seasonal variations in chemical weathering, associated CO2 consumption fluxes, and their control factors. The main ions were Ca2+, Mg2+, and HCO3−, which are characteristic of a drainage system on carbonate-dominated bedrock. The dissolved loads were derived from four major end-member reservoirs: silicate, limestone, dolomite, and atmosphere. The silicate weathering rates (SWRs) increased downstream from 0.03 t/km2/year to 2.37 t/km2/year. The carbonate weathering rates (CWRs) increased from 2.14 t/km2/year in the upper reaches, to 32.65 t/km2/year in the middle reaches, and then decreased to 23.20 t/km2/year in the lower reaches. The SWR values were 281.38 and 113.65 kg/km2/month during the high- and low-water periods, respectively. The CWR values were 2456.72 and 1409.32 kg/km2/month, respectively. The limestone weathering rates were 2042.74 and 1222.38 kg/km2/month, respectively. The dolomite weathering rates were 413.98 and 186.94 kg/km2/month, respectively. Spatial and seasonal variations in chemical weathering were controlled mainly by lithology, vegetation, and climate (temperature, water discharge, and precipitation). The CO2 consumption flux by chemical weathering was estimated at 189.79 × 109 mol/year, with 156.37 × 109 and 33.42 × 109 mol/year for carbonate and silicate weathering, respectively. The CO2 fluxes by chemical weathering are substantially influenced by sulfuric acid in the system. The CO2 flux produced by sulfuric acid weathering was estimated at 30.00 × 109 mol/year in the basin. Therefore, the Xi River Basin is a CO2 sink with a net consumption of CO2 flux of 3.42 × 109 mol/year.
Should I Stay or Should I Go? A Qualitative Exploration of Stigma and Other Factors Influencing Opioid Agonist Treatment Journeys
Authors: Carlisle Victoria Rice , Maynard Olivia M. , Bagnall Darren , Hickman Matthew , Shorrock Jon , Thomas Kyla , Kesten Joanna
Published: January 2023

(1) The harm-reduction benefits of opioid agonist treatment (OAT) are well-established; however, the UK government’s emphasis on “recovery” may be contributing to a high proportion of people leaving treatment and low retention rates. We wanted to develop a rich and nuanced understanding of the factors that might influence the treatment journeys of people who use OAT. (2) We explored factors at each level of the socioecological system and considered the ways these interact to influence treatment journeys in OAT. We carried out semi-structured interviews with people who use OAT (n = 12) and service providers (n = 13) and analysed data using reflexive thematic analysis. (3) We developed three themes representing participant perceptions of treatment journeys in OAT. These were: (1) The System is Broken; (2) Power Struggles; and (3) Filling the Void. (4) Conclusions: The data suggest that prioritisation of treatment retention is important to preserve the harm-reduction benefits of OAT. Stigma is a systemic issue which presents multiple barriers to people who use OAT living fulfilling lives. There is an urgent need to develop targeted interventions to address stigma towards people who use OAT.
Hope-Based Program for Portuguese Outpatients with Advanced Chronic Illness in a Community Setting: A Randomized Control Trial
Authors: Querido Ana , Laranjeira Carlos
Published: January 2023

Background: Hope is widely considered a subjective phenomenon able to bring beneficial consequences to human health and existence. Maintaining hope amid a life-threatening disease and during palliative care is critical. The study aims to examine the effectiveness of a psychosocial supportive Hope Promotion Program (HPP) in enhancing hope, comfort, and quality of life in Portuguese adult outpatients with advanced and progressive chronic illness. Method: Using a parallel Randomized Control Trial (RCT) with pre-post design, 56 cancer outpatients from two day hospitals. Participants were randomly assigned to either a control group (n = 28) or an intervention group (n = 28). The primary outcome measure was hope. Secondary measures included comfort and quality of life. Participants were assessed at baseline, day 15, and day 30 of follow-up. Results: Baseline characteristics were similar between the two groups. In the intervention group, there was a significant increase in the total hope scores after the HPP (day 15). Significant differences were still present after one month (p < 0.05). There was also a significant increase in comfort and quality of life scores in the intervention group one month after HPP (p = 0.018). Conclusions: The HPP may be an effective intervention to increase hope and improve comfort and quality of life among palliative patients. Future studies should increase sample size, diversify settings, and include longer and more detailed follow-ups.
Research on the Effect of Manufacturing Agglomeration on Green Use Efficiency of Industrial Land
Authors: Wang Yuan , Zhang Anlu , Min Min , Zhao Ke , Hu Weiyan , Qin Fude
Published: January 2023

Manufacturing agglomeration (MA) is an important way to achieve high-quality industrial development and promote land use efficiency in China. However, there is a lack of research on the relationship between MA and the green use efficiency of industrial land (GUEIL). Based on the panel data of 279 prefecture-level cities in China, from 2004 to 2019, this study analyzes the spatial and temporal differentiation characteristics of MA and GUEIL, then empirically analyzes the impact of MA on GUEIL. The results show that: (1) during the study period, the national MA levels showed a slight decline, followed by a small increase. In addition, the inter-regional differences are mainly characterized as eastern region > central region > northeast region > western region. (2) The national and regional GUEIL showed a trend of increasing, slightly decreasing, and then increasing again. The overall regional differences in efficiency show the characteristics of: eastern region > central region > western region > northeastern region. (3) At the national scale, MA had a “U-shaped” relationship with GUEIL; at the regional scale, MA had a significant “U-shaped” effect on GUEIL in the northeast, central and western regions, while having a single negative effect in the eastern region. Finally, this study provides suggestions for optimizing the manufacturing structure and improving the GUEIL.
Therapeutic Effects of Metaverse Rehabilitation for Cerebral Palsy: A Randomized Controlled Trial
Authors: Moon Ilyoung , An Yeongsang , Min Seunghwa , Park Chanhee
Published: January 2023

Metaverse physical therapy (MPT), an adjuvant technology for the rehabilitation of children with cerebral palsy (CP), has gained notoriety in the clinical field owing to its accessibility and because it provides motivation for rehabilitation. The aim is to compare the gross motor function and cardiopulmonary function, the activities of daily living, quality of life (QOL), and the perceived risk of coronavirus disease (COVID)-19 transmission between MPT and conventional physical therapy (CPT). A convenience sample of 26 children with CP (mean age, 11.23 ± 3.24 years, 14 females) were randomized into either the MPT or CPT group and received therapy three days/week for four weeks. Clinical outcomes included gross-motor-function measure 66 (GMFM-66), heart rate (HR), Borg-rating perceived exertion (BRPE), functional independence measure (FIM), pediatric QOL, and the risk of COVID-19 transmission. An analysis of variance showed that compared with CPT, MPT exerted positive effects on GMFM, HR, and BRPE. An independent t-test showed that compared with CPT, MPT exerted positive effects on the perceived transmission risk of COVID-19 but not on FIM and QOL. Our results provide promising therapeutic evidence that MPT improves gross motor function, cardiopulmonary function, and the risk of COVID-19 in children with CP.
Impact of COVID-19 in Patients with Lung Cancer: A Descriptive Analysis
Authors: Mojsak Damian , Dębczyński Michał , Kuklińska Beata , Minarowski Łukasz , Kasiukiewicz Agnieszka , Moniuszko-Malinowska Anna , Czupryna Piotr , Mróz Robert Marek
Published: January 2023

The COVID-19 pandemic poses a challenge to health systems worldwide. Limiting healthcare availability may delay early diagnosis and worsen the treatment effects of various diseases, including oncological diseases. We analyzed patients presenting to the 2nd Department of Lung Diseases and Tuberculosis in Białystok, Poland, with suspicion of lung cancer 12 months prior to the COVID-19 pandemic (pre-COVID-19) and, similarly, 12 months after the outbreak of the pandemic (mid-COVID). In total, 320 patients were analyzed—132 prior to and 188 after the COVID-19 outbreak. During the COVID-19 period, there was a lower percentage of patients presenting with ECOG performance status 0-1, with a noticeably increased percentage of patients with ECOG PS ≥2. The disease’s clinical stage (CS) was higher on admission during COVID-19. We observed more use of immunotherapy and more deaths before the start of treatment during the COVID-19 period. These results provide insight into the early effects of the COVID-19 pandemic on lung cancer patients and underscore the importance of conducting further studies to assess the long-term effects of the COVID-19 pandemic on this population.
The Right to Sexuality, Reproductive Health, and Found a Family for People with Intellectual Disability: A Systematic Review
Authors: Pérez-Curiel Patricia , Vicente Eva , Morán M. Lucía , Gómez Laura E.
Published: January 2023

Although sexuality, reproductive health, and starting a family are human rights that should be guaranteed for all citizens, they are still taboo issues for people with intellectual disability (ID), and even more so for women with ID. This paper systematically reviews the current qualitative and quantitative evidence on the rights of people with ID in regard to Articles 23 (right to home and family) and 25 (health, specifically sexual and reproductive health) of the Convention on the Rights of Persons with Disabilities (CRPD). A systematic review of the current literature, following PRISMA 2020, was carried out in ERIC, PsychInfo, Scopus, PubMed, ProQuest, and Web of Science. In all, 151 articles were included for review. The studies were categorized into six themes: attitudes, intimate relationships, sexual and reproductive health, sexuality and sex education, pregnancy, and parenthood. There are still many barriers that prevent people with ID from fully exercising their right to sexuality, reproductive health, and parenthood, most notably communicative and attitudinal barriers. These findings underline the need to continue advancing the rights of people with ID, relying on Schalock and Verdurgo’s eight-dimensional quality of life model as the ideal conceptual framework for translating such abstract concepts into practice and policy.
Impact of the Rise of Artificial Intelligence in Radiology: What Do Students Think?
Authors: Barreiro-Ares Andrés , Morales-Santiago Annia , Sendra-Portero Francisco , Souto-Bayarri Miguel
Published: January 2023

The rise of artificial intelligence (AI) in medicine, and particularly in radiology, is becoming increasingly prominent. Its impact will transform the way the specialty is practiced and the current and future education model. The aim of this study is to analyze the perception that undergraduate medical students have about the current situation of AI in medicine, especially in radiology. A survey with 17 items was distributed to medical students between 3 January to 31 March 2022. Two hundred and eighty-one students correctly responded the questionnaire; 79.3% of them claimed that they knew what AI is. However, their objective knowledge about AI was low but acceptable. Only 24.9% would choose radiology as a specialty, and only 40% of them as one of their first three options. The applications of this technology were valued positively by most students, who give it an important Support Role, without fear that the radiologist will be replaced by AI (79.7%). The majority (95.7%) agreed with the need to implement well-established ethical principles in AI, and 80% valued academic training in AI positively. Surveyed medical students have a basic understanding of AI and perceive it as a useful tool that will transform radiology.
Australian Women’s Responses to Breast Density Information: A Content Analysis
Authors: Pandya Tanvi , Liu Zixuan , Dolan Hankiz , Hersch Jolyn , Brennan Meagan , Houssami Nehmat , Nickel Brooke
Published: January 2023

Breast density (BD) is an independent risk factor for breast cancer and reduces mammographic sensitivity. This study explored women’s responses and intentions if notified that they had dense breasts. Methods: Content analysis was used to assess responses from a written questionnaire undertaken in conjunction with focus groups on BD involving 78 Australian women aged 40–74. Results: Half the women reported that they would feel a little anxious if notified they had dense breasts, while 29.5% would not feel anxious. The most common theme (29.5%) related to anxiety was the psychosocial impact of the possibility of developing cancer, and women believed that being better informed could help with anxiety (26.9%). When asked what they would do if notified of having dense breasts, the most common response was to consult their doctor for information/advice (38.5%), followed by considering supplemental screening (23%). Consequently, when asked directly, 65.4% were interested in undergoing supplemental screening, while others (10.3%) said they “wouldn’t worry about it too much”. Discussion: These findings have important implications for health systems with population-based breast screening programs that are currently considering widespread BD notification in terms of the impact on women, health services and primary care.
Understanding the Lives of Aboriginal and Torres Strait Islander Women with Traumatic Brain Injury from Family Violence in Australia: A Qualitative Study Protocol
Authors: Fitts Michelle S. , Cullen Jennifer , Kingston Gail , Johnson Yasmin , Wills Elaine , Soldatic Karen
Published: January 2023

Globally, there is growing recognition of the connection between violence and head injuries. At present, little qualitative research exists around how surviving this experience impacts everyday life for women, particularly Aboriginal and Torres Strait Islander women. This project aims to explore the nature and context of these women’s lives including living with the injury and to identify their needs and priorities during recovery. This 3-year exploratory project is being conducted across three Australian jurisdictions (Queensland, Northern Territory, and New South Wales). Qualitative interviews and discussion groups will be conducted with four key groups: Aboriginal and Torres Strait Islander women (aged 18+) who have acquired a head injury through family violence; their family members and/or carers; and hospital staff as well as government and non-government service providers who work with women who have experienced family violence. Nominated staff within community-based service providers will support the promotion of the project to women who have acquired a head injury through family violence. Hospital staff and service providers will be recruited using purposive and snowball sampling. Transcripts and fieldnotes will be analysed using narrative and descriptive phenomenological approaches. Reflection and research knowledge exchange and translation will be undertaken through service provider workshops.
Pros and Cons of Immediate Sequential Bilateral Cataract Surgery from a Patient Perspective: A Survey
Authors: Obuchowska Iwona , Micun Zuzanna , Młynarczyk Maryla , Dmuchowska Diana Anna , Konopińska Joanna
Published: January 2023

The aim of the study was to analyze patients’ experiences with immediate sequential bilateral cataract surgery (ISBCS). An anonymous survey was sent by post to patients who underwent ISBCS between 1 May 2020 and 30 April 2022. A total of 195 participants completed the survey. Specifically, 94.6% of the respondents were satisfied with the possibility of having both eyes treated during one surgical procedure, 89.7% would choose ISBCS again if offered a choice, and 89.2% would recommend this procedure to their family members. ISBCS provided a subjective benefit for 84.6% of the respondents. The most commonly reported ISBCS-related problems were the necessity to sleep in a supine position (32.8%), inability to read shortly after the surgery (27.7%), having both eyes protected with a dressing (24.6%), and application of eyedrops to both eyes at the same time (17.4%). All patients were able to identify some pros of ISBCS, with the most common being single stay in the operating room (82.6%), lower number of visits to the clinic (62.6%), quick normalization of eyesight (61%), time savings for family members (54.9%), quick adjustment of reading glasses (32.3%), and economical aspects (23.6%). The perception of difficulties associated with ISBCS and the benefits offered by this procedure differed depending on patients’ gender, age, marital status, education, place of residence, occupational activity, level of care dependence, and everyday activities. Understanding patients’ opinions about ISBCS provides insight into the advantages and disadvantages of this procedure from a broader perspective.
Secular-Trend Analysis of the Incidence Rate of Lung Squamous Cell Carcinoma in Taiwan
Authors: Shen Xiao-Han , Chang Yung-Yueh , Pham Rong-Qi , Chen Wei-An , Li Fang-Yu , Huang Wan-Chin , Lin Yu-Wen
Published: January 2023

Lung cancer is the leading cause of cancer deaths worldwide, and squamous cell carcinoma (SQC) is Taiwan’s second most common lung carcinoma histotype. This study aimed to investigate changes in the long-term trend of the SQC incidence rate in Taiwan. SQC cases between 1985 and 2019 were adopted from Taiwan‘s Cancer Registry System; the age-adjusted incidence rate was calculated using the World Standard Population in 2000. The long-term trends of the age, period, and birth cohort effect of SQC incidence rates were estimated using the SEER Age-Period-Cohort Web Tool. The results revealed that the incidence of lung carcinoma in Taiwan increased, while the incidence of SQC exhibited a slight decrease during this study period. The age rate ratio (ARR) of the incidence rate in men declined gradually, and the period effect changed more slowly for women than men. The cohort effect formed a bimodal curve. The annual percentage change results for women indicated that the ARR decreased from 1.652 (95% confidence interval (CI): 1.422, 1.9192) at 30 to 34 years to 0.559 (95% CI: 0.4988, 0.6265) at 75 to 79 years; the period effect decreased from 1.2204 (95% CI: 1.1148, 1.336) in 1995 to 1999 to 0.608 (95% CI: 0.5515, 0.6704) in 2015 to 2019, with a greater decline in the later period. The cohort effect was unimodal, with the SQC risk value peaking in the 1915 birth cohort and exhibiting a steady decline thereafter. The results of this study suggest that a decrease in the smoking rate may be the reason for the decline in the incidence of SQC, and we observed a similar trend between SQC and the smoking rate in men.
Protocols and Features of Goal-Setting-Based Intervention for Frail Older Adults in Community Exercise Facilities
Authors: Yamashita Masashi , Mashizume Yuki , Yama Kento , Sasaki Shun , Uehara Daiki , Kamiya Kentaro
Published: January 2023

Appropriate goal setting for frail older adults is important because it drives effective rehabilitation. However, more insights into the types and degrees of frailty and goal-setting trends should be obtained. We conducted a multicenter prospective study to qualitatively examine the relation between each frailty domain (physical, social, and cognitive) and the goals of 201 subjects (median age: 79, 43.8% male) who began rehabilitation at a long-term care prevention facility. Goal setting was determined by the specific, measurable, achievable, relevant, and time to goal (SMART) framework up to three months, categorized according to the International Classification of Functioning, Disability, and Health. The results showed that approximately 90% of the subjects had frailty in at least one domain, and about half had frailties in two or more domains. In total, 176 (87.6%) subjects had goals corresponding to activities and participation. The tendency to set goals to improve mobility was confirmed when the number of overlapping frailties was high, especially those in the physical and social domains. Those with milder frailties were more likely to establish goals targeting improvements in community, social, and civic life. These findings will lead to the development of practical goal-setting guidelines for frail older adults.
Geopolitical Risk Evolution and Obstacle Factors of Countries along the Belt and Road and Its Types Classification
Authors: Hu Wei , Shan Yue , Deng Yun , Fu Ningning , Duan Jian , Jiang Haining , Zhang Jianzhen
Published: January 2023

As a great practice of building a community of shared future for mankind, the Belt and Road Initiative is facing geopolitical risk brought by great power games, regional conflicts and terrorism. It is an important mission of geopolitical research to scientifically deal with the geopolitical risk along the Belt and Road. This study systematically constructs the geopolitical risk assessment index system and analyzes the spatiotemporal evolution, obstacle factors and risk types of geopolitical risk of countries along the Belt and Road by using the entropy weight TOPSIS model, obstacle degree model and minimum variance method. The research results showed that: (1) From 2005 to 2020, the polarization of geopolitical risk in countries along the Belt and Road was very significant, and the overall trend of geopolitical risk tended to deteriorate. (2) The Middle East and Eastern Europe were the most important geopolitical risk zones along the Belt and Road, and Afghanistan, Iraq, Russia and Ukraine were the main high geopolitical risk centers, with significant risk spillover effects from these centers. (3) Terrorism and close relations with the United States were the most important obstacle factors for geopolitical risk in countries along the Belt and Road, and military intervention politics, trade dependence degree and foreign debt burden were important obstacle factors for geopolitical risk in countries along the Belt and Road. (4) Geopolitical risk along the Belt and Road can be divided into sovereign risk dominant type, sovereign and military risk dominant type, sovereign and major power intervention risk dominant type, and sovereign and military and major power intervention risk jointly dominated type, among which sovereign and military and major power intervention risk jointly dominated type was the most important geopolitical risk type. In order to scientifically deal with geopolitical risk in countries along the Belt and Road, it is necessary to strengthen geopolitical risk awareness, pay attention to the dominant geopolitical risk factors, strengthen the control of regional geopolitical risk spillover and formulate reasonable risk prevention and control scheme based on geopolitical risk types.
Analysis of Spatiotemporal Changes of Ecological Environment Quality and Its Coupling Coordination with Urbanization in the Yangtze River Delta Urban Agglomeration, China
Authors: Shi Zhiyu , Wang Yating , Zhao Qing
Published: January 2023

It is inevitable that urban agglomeration will have a coercive impact on the regional Ecological Environment Quality (EEQ) as a consequence of high-speed urbanization. Balancing the EEQ and urbanization development has become a problem worthy of attention. In order to objectively evaluate the EEQ of the Yangtze River Delta Urban Agglomeration (YRDUA) and explore the impact of the urbanization process on it, this paper is based on the Modified Remote Sensing Ecological Index (MRSEI) and the Comprehensive Night Light Index (CNLI), respectively, and conducts a quantitative assessment of the YRDUA in China from 2000 to 2020. The results show that: (1) From 2000 to 2020, the MRSEI of the YRDUA first decreased and then increased, and the ecological environment quality degraded first and then improved; however, there were significant differences between regions. The ecological environment quality in the south is obviously better than that in the north, and the ecological environment quality in the north changes more drastically, and the low value area of MRSEI will gradually move downstream as time changes; (2) During the study period, the YRDUA formed a hierarchical and progressive urbanization pattern. The inland urbanization process expanded from east to west along the Yangtze River, and the urbanization process of coastal cities expanded from Shanghai as the center to the north and south with high-intensity urbanization cities concentrated in Shanghai and its surrounding cities and low-intensity urbanization cities distributed in the western part of the urban agglomeration; (3) The Coupling Coordination Degree (CCD) between urbanization and EEQ in the YRDUA has continuously improved with an increase of 28.57% in the past 21 years, and the number of cities with high level coupling continues to rise, while the number of medium level coupling cities and low level coupling cities has declined. As a large-scale and long-term analysis of changes in the EEQ and the urbanization process, this study can provide theoretical support for policymakers to formulate mesoscale development planning, EEQ monitoring, and environmental protection policies.
Differential Regulation of Innate Lymphoid Cells in Human and Murine Oral Squamous Cell Carcinoma
Authors: Syed Sofia Ali , Qureshi Muhammad Asif , Khan Saeed , Kumar Rajesh , Khyani Iqbal A. Muhammad , Khan Bilal Ahmed , Safdar Jawad
Published: January 2023

Oral squamous cell carcinomas (OSCC) remain a major healthcare burden in Asian countries. In Pakistan alone, it is the most common cancer in males and second only to breast cancer in females. Alarmingly, treatment options for OSCC remain limited. With this context, investigations made to explore the inflammatory milieu of OSCC become highly relevant, with the hope of practicing immunotherapeutic approaches to address this highly prevalent tumor. We investigated the newly identified innate lymphoid cells (ILCs) and associated cytokines in well-defined human oral squamous cell carcinoma (OSCC) as well as in a 7,12-dimethylbenz[a]anthracene (DMBA)-induced murine model of OSCC using flow cytometry and quantitative real-time polymerase chain reaction (qPCR). We further went on to explore molecular circuitry involved in OSCC by developing a murine model of OSCC and using an α-Thy1 antibody to inhibit ILCs. Amongst the ILCs that we found in human OSCC, ILC3 (23%) was the most abundant, followed by ILC2 (17%) and ILC1 (1%). Mice were divided into four groups: DMBA (n = 33), DMBA+antibody (Ab) (n = 30), acetone (n = 5), and control (n = 5). In murine OSCC tissues, ILC1 and ILC3 were down-infiltrated, while ILC2 remained unchanged compared to controls. Interestingly, compared to the controls (DMBA group), mice treated with the α-Thy1 antibody showed fewer numbers of large tumors, and a larger percentage of these mice were tumor-free at this study’s end point. We present novel data on the differential expansion/downsizing of ILCs in OSCC, which provides a pivotal basis to dive deeper into molecular circuitry and the OSCC tumor niche to devise novel diagnostic, therapeutic, and prognostic strategies to prevent/treat oral cancers.
Antimicrobial Clothing Based on Electrospun Fibers with ZnO Nanoparticles
Authors: Preda Manuela Daniela , Popa Maria Leila , Neacșu Ionela Andreea , Grumezescu Alexandru Mihai , Ginghină Octav
Published: January 2023

There has been a surge in interest in developing protective textiles and clothes to protect wearers from risks such as chemical, biological, heat, UV, pollution, and other environmental factors. Traditional protective textiles have strong water resistance but lack breathability and have a limited capacity to remove water vapor and moisture. Electrospun fibers and membranes have shown enormous promise in developing protective materials and garments. Textiles made up of electrospun fibers and membranes can provide thermal comfort and protection against a wide range of environmental threats. Because of their multifunctional properties, such as semi-conductivity, ultraviolet absorption, optical transparency, and photoluminescence, their low toxicity, biodegradability, low cost, and versatility in achieving diverse shapes, ZnO-based nanomaterials are a subject of increasing interest in the current review. The growing uses of electrospinning in the development of breathable and protective textiles are highlighted in this review.