bluuebunny/crossref_metadata_2025 huggingface dataset:
Кяхтинская железная дорога: геоэкономический проект Российской империи с целью развития торговых связей с Китаем и Монголией
Authors:   Ural Federal University (19, Mira St., 620002 Yekaterinburg, Russian Federation), Hamzin Ildar R. , Ganiev Rustam T. , Kochnev Anton V.
Published: June 2023

Introduction. In the late 19th and early 20th centuries, Imperial Russia tended to prioritize the creation of trade and transport communications with countries of the East, which was vividly manifested in a number of projects, such as the Trans-Siberian Railway, Chinese Eastern Railway, and South Manchuria Railway. In this regard, not that widely known remains the Kyakhta Railway project, which implied a construction of a railway line from the Trans-Siberian Railway to Kyakhta with subsequent access to the territory of Mongolia. Goals. The paper attempts an analysis of how the concept of the Kyakhta Railway was evolutionizing throughout the late 19th and early 20th centuries, and seeks to reveal some key features arising from the latter’s geoeconomic and geopolitical objectives. Materials and methods. The work involves understudied materials stored at the Russian State Historical Archive, and methodologically rests on a systemic historical approach that secures insights into the development of the project from the perspectives of Imperial Russia’s political and economic interests and opportunities across Asia at the turn of the 20th century. Results. The conducted analysis of documents shows how the Kyakhta Railway project was actually developing. So, the earliest initiatives to build a railway line from Kyakhta to China’s northern borders were announced at the beginning of the 20th century, after Chinese authorities decided to lay a Beijing–Kalgan railway line. The Government was showing interest in the project under study in the direct aftermath the Russo-Japanese War of 1904–1905. And the project’s complete concept was introduced in a special note prepared by Kyakhta-based merchants in 1910 — to be finally approved in 1913. However, the outbreak of WWI postponed its implementation indefinitely. The article examines each stage in the shaping of the Kyakhta Railway project with emphases be laid on its geoeconomic and geopolitical objectives. The paper shows the project was viewed as a means to solve the then problems of Russian-Chinese and Russian-Mongolian trade, stimulate Eastern Siberia’s economy, fulfill transit potentials of Russia, and strengthen our geopolitical influence in the territory of Mongolia. Conclusions. The work attests to the Kyakhta Railway project was systemic and multifactorial by nature, illustrates its essential place in the overall geoeconomic strategies of the Russian Empire.
Миграции населения в г. Элисту в первые годы строительства. 1927–1932 гг.
Authors:   Kalmyk Scientific Center of the RAS (8, Ilishkin St., Elista 358000, Russian Federation), Belousov Sergey S.
Published: June 2023

Introduction. The article examines the history of population migrations in the earliest period of Elista city’s construction between 1927 and 1932. An insight into the topic shall further reveal common and specific features in the shaping of settlement populations across Russia. Goals. The paper aims to analyze actual migration trends during the construction of the city to have gained the status of an autonomy’s capital — and show the Government’s impacts on the formation and development of Elista’s population t in 1927–1932. Materials and methods. The study employs the historical-comparative and historical-genetic research methods, analyzes documents from the National Archive of Kalmykia, republican periodicals and published monographs dealing with the history of Elista, a number of archival documents be newly introduced into scientific circulation. Results. The work reveals causes and factors of the creation of Kalmykia’s capital, analyzes population policies of Soviet authorities, reviews social, professional, ethnic, and territorial backgrounds of immigrants. The analysis of documents attests to that it was the Soviet Government that played a key role in the city’s creation and approved major directions of its development, organized the relocation of administrative agencies and funded the bulk of its construction. The migration agenda was being implemented in accordance with the goals of nationalities and administrative policies, as well as with directions of the city’s development chosen by official authorities. The government-organized relocations were administrative by nature. However, the population structure was essentially shaped by unorganized migrations that resulted from the sedentarization of Kalmyks, aspirations of some citizens from neighboring regions and territories to obtain better sources of livelihood — or even to escape political persecution. Conclusions. The emergence of the new settlement was driven by that the Government was seeking to establish a Soviet ethnic center of the Kalmyk people and administer the territory from inside Kalmyk Autonomous Oblast. These presupposed migrations were to be planned and facilitate achieving the objectives set by authorities. There had been no plans to create large industrial facilities in the city, so the government-organized migration did not require involvement of large labor resources. The ‘unorganized’ resettlers were largely those who had some professional skills demanded in the city, nomads seeking a sedentary life, and individuals in pursuit of profitable livelihoods or shelter from the watchful eye of law enforcement agencies.
Перевод рыбной промышленности Калмыкии во второй половине 1930-х гг. в положение военного времени
Authors:   Kalmyk Scientific Center of the RAS (8, Ilishkin St., Elista 358000, Russian Federation), Maksimov Konstantin N.
Published: June 2023

Introduction. In the 1920s–1930s, the mobilization of human and material resources played a huge role in the process of reforming the Red Army and strengthening the country’s defense capability. The period witnessed measures aimed to prepare forces and means for the development of the Soviet armed services and protection of the country. The preparation system also included economic (food) mobilization not only for the current army allowance but also for investing the necessary material reserves in case of wartime, to secure uninterrupted supply of the army during a war. Goals. The article attempts an analysis of how Kalmykia’s fishing industry was converted to the wartime agenda in the mid-to-late 1930s. Results. Along with the delivery and procurement of agricultural and livestock products to the government, the supply of fish products is considered in the article not only as an aspect of mass catering, food security, exports — but also as a means to meet the needs of the army and secure the country’s defense. The development of Kalmykia’s fishing industry in the mid-to-late1930s across the Volga-Caspian basin resulted in a significant contribution to the supply of fish products for special consumers (military) according to orders of the People’s Commissariat for Fishing Industry of the USSR.
Safety and efficacy of BI 695501 versus adalimumab reference product in patients with advanced Crohn’s disease (VOLTAIRE-CD): a multicenter, randomized, double-blind, phase 3 trial
Authors: Hanauer Stephen
Published: June 2023

Adalimumab is a type of drug known as a biologic used for chronic inflammatory diseases, such as Crohn’s. In these medical conditions, a protein called TNF is overproduced in the affected part of the body, which causes inflammation and damage. Adalimumab blocks the action of TNF to reduce this inflammation.
The FDA defines a biosimilar as a biological product that is highly similar to and has no clinically meaningful differences in safety and effectiveness to an existing FDA-approved reference product. This means that there are more treatment options for chronically ill patients at a potentially lower cost.
BI 695501 is an adalimumab biosimilar that has already demonstrated similar efficacy, safety and immunogenicity to adalimumab reference product in patients with chronic plaque psoriasis and rheumatoid arthritis.
In this video, Professor Stephen Hanauer discusses the VOLTAIRE-CD study, which aimed to compare the safety and efficacy of the BI 695501 biosimilar in Crohn’s disease.
A Study of Social Intelligence among College Students in Himachal Pradesh, India
Authors: Pratap Nibha , Sira Dr. Raminder Kaur
Published: June 2023

Abstract: The ability to make sense of the actions of others is critical to people’s daily functioning. Humans are social beings and are often said to social experts. They understand that people’s actions are directed at goals and are driven by intentions. The present study is done with the purpose to examine and measure the Social intelligence and academic achievement among college students of Himachal Pradesh. For the study, the samples were selected on the basis of a random sampling technique which consisted of 280-degree college students (Management = 150 and Social Science= 130) selected from various degree colleges of Himachal Pradesh. The factors of social intelligence included for the study are Patience, Cooperativeness, Confidence, Sensitivity, Tactfulness, Sense of Humor, Recognition of Social Environment, and Memory. A standardized questionnaire of SI by N.K. Chadha and Usha Ganeshan were administrated for this purpose. Proper statistical tools and analysis were applied in order to obtain the results. The study indicates that Social science college students have better social intelligence than Management college students. However, it was found that Management students have better academic achievement than their Counterparts.
Use of Waste Tyre in Concrete
Authors: Dewangan Nupur
Published: June 2023

Abstract: Waste tyre rubber disposal has become a major environmental concern in all parts of the world, posing a serious threat to the environment. One potential application for scrap tyre rubber is to mix it into concrete to replace some of the natural material. Every year, an estimated 1000 million tyres reach the end of their useful lives, with another 5000 million predicted to be thrown on a regular basis by 2030. Currently, only a small portion is recycled, and millions of tyres are just stacked, landfilled, or buried. This not only reduces pollution caused by waste tyres, but it also reduces the usage of conventional aggregate, which is limited in supply.As per the mix design specifications, the rubber pieces (rubber aggregate) were sieved through a 25 mm sieve and held at a 20 mm sieve before being added to the concrete mix at 3.5,5.5,7.5 percent by weight of the aggregate. This study investigates the beneficial impact of waste tyre rubber particles on several concrete characteristics. The used rubber scraps are obtained through the mechanical trituration of used tyres from automobiles and trucks. They have long been researched for resource reutilization as an aggregate in concrete, resulting in the 'Rubcrete mix,' which may be easily used in a variety of applications with promising results. Rubcrete produces a finished product with good mechanical qualities and also represents an efficient and cost-effective method of recycling waste tyres. The purpose of this paper is to report the findings of an experimental examination into the ideal types and quantities of aggregates in concrete mixtures for engineering purposes. The following parameters were investigated: density of rubber aggregates, workability, air entrapment, and compressive strength. In rubberized concrete mixtures, three types of rubber particles (ash rubber, crumb rubber, and tyre) were utilised to partially or totally replace natural aggregates.
Machine Learning Approach for Detection of Phishing Website
Authors: Pawar Nikita , Tijare Dr. Pritish
Published: June 2023

Abstract: Phishing attacks are the easiest way to get sensitive information from innocent users. The purpose of phishing is to obtain critical information like the private information of users. Phishing sites pretend to be relevant sites and it is more difficult to distinguish these sites. It is one of the greatest threats that every individual and management has ever faced. URLs are referred to as web pages through which users locate pieces of information on the Internet. This paper focuses on phishing website detection which is important for the prevention of our sensitive information. There are different types of websites with different features. Therefore, we need to use a specific set of features on websites to protect against phishing. A machine learning model has been proposed to detect phishing websites. To detect phishing sites, we proposed the machine learning model. The essential objective of this paper is to classify the various algorithm of machine learning by extracting and analyzing various features of legitimate and phishing URLs.
A Chemical Synthesis of CdSnO 3 Nanoparticles and their Performance in Hydrogen Sensing
Authors: Talele V. V.
Published: June 2023

Abstract: CdSnO3 nanoparticles were successfully synthesized without any templates by simple co-precipitation synthesis route. Further characterized by using X-ray diffraction (XRD) measurements, field emission scanning electron microscopy (FESEM) and Fourier transform infrared (FTIR) spectroscopy and their hydrogen sensing properties were investigated. The CdSnO3 nanoparticles exhibited outstanding gas sensing characteristics such as, higher gas response, extremely rapid response, fast recovery, excellent repeatability, good selectivity and at ambient operating temperature (~ 30C). Furthermore, the CdSnO3 nanoparticles can detect up to 5 ppm for hydrogen with reasonable sensitivity at an ambient operating temperature.
An Efficient Approach for Mitigating Insecure Direct Object Reference (IDOR) Bug Bounty Method
Authors: Singh Shivam , Dandotiya Monika
Published: June 2023

Abstract: This real-time paper explores Insecure Direct Object Reference (IDOR) vulnerabilities in the context of bug bounty programs. It provides an overview of IDOR attacks and their impact on web application security. The paper discusses common IDOR vulnerabilities, including how they can be discovered and exploited by attackers. It also highlights the importance of implementing proper access controls and other security measures to prevent IDOR attacks. The paper concludes with a discussion of best practices for identifying and mitigating IDOR vulnerabilities in bug bounty programs, including the use of manual testing
Analysing Volatility Dynamics of India and US Stock Market
Authors: Aggarwal Dr. Mamta , Bamba Dr. Meera , Bansal Indu
Published: June 2023

Abstract: Analysing the risk-return trade-off of financial assets, volatility is a key factor. Volatility promotes market liquidity and demonstrates the effectiveness of the financial system. To have an insights of India And US Market Volatility behaviour, this paper examines the volatility dynamics of India And US Stock market by taking Sensex And S & P 500 daily closing prices for the 2nd January 2003 to 31st December 2019. The authors have two questions to examine about volatility whether India and US stock market volatility shows volatility clustering and volatility persistence or not. ARCH LM test and Ljung Box Q2 statistics were used to check for volatility clustering. And for volatility persistence GARCH (1,1) model is used. The results of the study confirm the presence of volatility clustering in in both India And US stock market. Additionally, Indian stock return volatility shows lower volatility persistence than US. The results of the study are quite useful for the academicians, policy makers and investor community in general
Effect of Al-Qur’an Therapy on Anxiety Cancer Patients in Aisyiah Islamic Hospital Malang, Indonesia
Authors: Rosyidul 'Ibad Muhammad , Napik Ahmad Miftakul
Published: June 2023

Cancer is a disease that many have a threat to the people with cancer, so that the patient will arise anxiety disorder if the threat factor is not overcome. Anxiety in cancer sufferers will be bad, such as difficulty to rest, disrupted cell regeneration process, decreased endurance, and decreased interest to continue treatment or therapy. Quran sound therapy is one of the anxiety disorders therapy that is easy and efficient, because of its ease of doing, minimal side effects, and economical. Method in this study is pre-expirimental, with independent variable is the sound therapy of Qur'an, while the dependent variable is the anxiety of cancer patients. The sampling technique used purposive sampling with 24 samples of cancer patients. The instrument used is the HARS scale (Hamilton Anxiety Rating Scale). Data analysis using Wilcoxon Test. Results of the research before the action of majority cancer patients experienced moderate anxiety, whereas after the actions of majority cancer patients experienced mild anxiety. The result of the significance value is 0,000 which is greater than the value of α (0.05). Counclusion from this research is the Qur’an voice theraphy influence to reducing the anxiety of cancer patient’s
Discharge Planning on Congestive Heart Failure Patients who were Readmission after Hospitalization
Authors: Hidayah Nurul , Kurniawati Dian Aulia , Umaryani Dewi Siti Nurkhasanah , Ariyani Novi
Published: June 2023

Introduction: Congestive Heart Failure is the inability of the heart to maintain adequate cardiac output to meet metabolic and oxygen requirements in the tissues despite adequate venous return.Objectives: to analyze a correlation of Congestive Heart Failure discharge planning and readmission after hospitalization.Methods: The study was conducted at ICCU Tidar Magelang hospital with 27 Congestive Heart Failure (CHF) patients who had readmission after hospitalization. The sampling technique was done by consecutive sampling technique. Data analysis in this study used Chi square.Results: The results of the statistical test (Chi Square) show that 1 cell (25.0%) with an expected value <5 means that the cell (box) with the expected value is below 5 is 25.0%. The minimum expected value is 2.96 meaning that there is no expected value <1. Continuity correction with p value = 0.002. The p-value of Fisher's Exact Test = 0.001. The results of the Symmetric Measure table (correlation test) obtained the value of the Contingency Coefficient (r) = 0.561 with a value of p = 0.000.Conclusions: The conclusion of this statistical test is that there is a correlation of Congestive Heart Failure (CHF) discharge planning and readmission after hospitalization.
Effectiveness of Melpredia Prediabetes Self Management Education Based on Android Applications on HbA1c Levels in People with Prediabetes
Authors: Hakim Amelia Nurul , Rumahorbo Hotma , Sudirman Sudirman
Published: June 2023

Introduction: Prediabetes is a condition that will develop into type 2 Diabetes Mellitus (DMT2) within 3-5 years. Glycaemic control is the primary intervention in long-term management, so structured education with appropriate and sustainable media is needed using mobile health technology. Objectives: The development of the "Melpredia" application based on an android application as a media for health promotion and its effect on HbA1c glycaemic control and self-care management. Methods: The Research type was Research and Development (R&D), and model testing using Quasi-experiments with pre-test post-test control group design was carried out for three months from January to April 2021. The purposive sampling technique consisted of 15 intervention groups and 15 control groups. The data were tested using Paired t-test and an independent t-test. The research instrument used by application "Melpredia." Results: The Android-based Melpredia application obtained a percentage of 89% (Fair) and the feasibility test for material aspects with a percentage of 90% (excellent). Using the Melpredia application has the effect of Prediabetes Self-Management Education based on an android application on HbA1c levels of 5.927 ± 0.1831 in people with prediabetes than conventional health promotion (p = 0.001). Conclusions: Application "Melpredia" android based and can effectively improve the HbA1c levels and self-care management of prediabetes in preventing diabetes mellitus by utilizing educational menu, meal planning, physical activity, and reminders use applications. "Melpredia" is more effective than conventional.
Patient Satisfaction Level at the Outpatient in University of Muhammadiyah Malang Hospital
Authors: Ruhyanudin Faqih , Zanah Miftachul , Sunardi Sunardi , Fikri Zahid
Published: June 2023

Introduction: The hospital is one of the health care facilities expected to provide appropriate health services and information for patients and the broader community. Patient satisfaction is one of the essential things for health care providers as a measuring tool to evaluate service quality. Satisfaction can increase the number of visits that impact increasing sources of income for hospitals and, at the same time, realize a healthy and prosperous society. Objectives: The purpose of this study was to identify patient satisfaction in the outpatient installation of the Muhammadiyah Malang University Hospital in indicators of conformity with expectations, ease of obtaining services, and willingness to recommend. Methods: The design of this research is descriptive observational. The sample in this study were patients who visited the outpatient installation of the University of Muhammadiyah Malang Hospital in November 2020; as many as 136 respondents were selected by accidental sampling. Data collection with a patient satisfaction questionnaire. Data analysis with descriptive analysis and presented in the frequency distribution. Results: The results showed that as many as 68.4% of respondents stated that the service was as expected, 52.2% were easy to access services, 50.7% were willing to recommend to other parties, and 54.4% said they were satisfied. Conclusions: Patient satisfaction with the University of Muhammadiyah Malang Hospital in several indicators is relatively high, but it needs improvement in several respects. Nurses, doctors, and other human resources need to maintain good service delivery by providing appropriate, fast, always smiling, and friendly service to patients.
Respiratory status and behavioral response of premature infant with nesting model care approach in neonatal intensive care unit
Authors: Tuti Seniwati  , Nurmaulid Nurmaulid , Abdul Kadir  , Irmayanti Irmayanti
Published: June 2023

Introduction: The increase in mortality of newborns, especially premature babies, is caused by non-optimal lung development where the production of less surfactant triggers lung collapse and compliance. This causes stress on the newborn and requires more intensive care. One of the care taken to overcome these problems is the nesting application. Objectives: To identify the effect of nesting model care on premature infants' respiratory status and behavioral responses. Methods: This study is a quasi-experimental design with a pre-post-test group design. The samples were premature infants admitted to the Neonatal Intensive Care Unit (NICU), with as many as 40 respondents. The sampling technique is purposive sampling. Data were analyzed using the Mann-Whitney test and Wilcoxon test. Results: The results showed no significant differences between the respiratory status in modern and conventional nesting, with P-value = 0.292. While there was a significant difference in behavioral responses, both groups with P = 0.027. There was an effect on respiratory status before and after nesting in the modern nesting group where the significance P = 0.001 and no effect in the conventional nesting group with a P value = 0066. Regarding behavioral responses, there was a significant value in two of the group before and after nesting, where the value significance respectively P = 0.009 and P = 0.025. Conclusions: Modern nesting influences scores and behavioral responses in premature infants, while conventional nesting only affects reducing the score of behavioral responses. It is expected that the use of nesting in the NICU room specifically for premature babies prefers the use of modern nesting compared to conventional nesting babies to maintain stability in terms of both respiratory and response behavior.
effect of changes in co2, plasma protein, and hemoglobin on increasing blood acidity of patients with respiratory acidosis in the ICU room, dr. Slamet Martdirjo Pamekasan
Authors: Rahman Taufiqurrahman , Suryadi Amin Edy , Syakura Abdan
Published: June 2023

Backgrounds: Character education is currently one of the solutions to overcome moral decline. From a psychological point of view, the character describes several potentials. Objectives: This study aims to determine the effect of P2KK on the soft skills of students at the University of Muhammadiyah Malang. Methods: The research design used was a pre-experimental group pre-posttest design. Sampling in this study used non-probability sampling with a quota sampling technique. The samples used were 100 students of the University of Muhammadiyah Malang class of 2018 who took part in P2KK batches 24 and 25. Data collection used the LEQ (Life Effectiveness Questionnaire) questionnaire with data analysis using the Wilcoxon test. Results: Soft skills of University of Muhammadiyah Malang students before participating in P2KK 72% had a medium category with an average value of 140, and soft skills after P2KK 76% had a medium category with an average value of 15. Based on the results of data analysis using the Wilcoxon test, significant results were obtained (p =0.00), meaning there are differences in soft skills before and after P2KK. Conclusion: There is an effect of P2KK on the soft skills of students at the University of Muhammadiyah Malang with an experiential learning approach that can improve soft skills. The most significant influence is on the attribute of controlling emotions. The UPT recommends it. P2KK to find out and evaluate the soft skill character of P2KK participants so that the training can specifically improve the soft skills that are lacking.
The correlation between self awareness and prediabetes status in patients with excess weight in polyclinic of Baladhika Husada Hospital Jember
Authors: Sukma Anindianti , Sutawardana Jon Hafan , Kushariyadi Kushariyadi
Published: June 2023

Introduction: Poor lifestyle and eating patterns can cause energy imbalances, which can cause excess weight. Excess weight increase risk of pre-diabetes than healthy body weight. Many people who do not know they have pre-diabetes, they have lack of self-awareness to prevent diabetes mellitus. Objectives: This research aims to determine the relationship between self-awareness and pre-diabetes status in patients with excess weight in Polyclinic of Baladhika Husada Hospital in Jember. Methods: This research uses an analytic design with a cross-sectional approach. There were 84 respondents obtained from the accidental sampling technique. Data were collected from the Self Awareness Diabetes Mellitus and random blood glucose results. Data were analyzed using Spearman-rank. Result: Based on the statistical test results, there was a significant relationship between self-awareness and prediabetes status with the direction of negative correlation, which means the higher the self-awareness, the lower the respondents have prediabetes. In patients who were overweight, there was a buildup of fat in the body that can reduce insulin work, which affects prediabetes. While self-awareness as an attitude that must be possessed by someone with excess weight to prevent the risk of prediabetes. Discussion: This study showed the importance of increasing self-awareness and implementing blood glucose control routinely so that someone who has entered the prediabetes category can improve their lifestyle to prevent diabetes mellitus.
Education model on SMS gateway on blood sugar levels of diabetes mellitus patients
Authors: Febriyanti Febriyanti , Yusril Viki , Guci Asriwan
Published: June 2023

Introduction: Diabetes has become a global epidemic over the last two decades, the prevalence has doubled, from 4.6% to 9.3% in the population aged 20-79 years. Based on data from the International Diabetes Federation (IDF) 2019, it is estimated that 463 million people in the above age group live with diabetes of which 90% Diabetes, Indonesia faces the same diabetes threat as the world, within five years. West Sumatra is at number 21 out of 34 provinces with diabetes cases. Based on data from the Padang City Health Office in 2020, from 23 health centers in Padang City, Andalas Health Center is the highest coverage of type 2 diabetes mellitus, which is 1017 people. Of the 10 sub-districts in the Andalas Community Health Center working area, Jati sub-district is the highest case of diabetes mellitus. Good blood sugar control is one of the important factors and has been shown to reduce the risk of complications in people with diabetes, to achieve good blood glucose control, holistic management is needed including education, education with an SMS gateway approach can provide continuous and continuous information. Objectives: see the effect of SMS gateway-based education model on blood sugar levels of diabetics. Methods:  Pre-experiment using the One Group Pretest-Posttest design approach. Data analysis using Paired T-test sample. Results: The results showed that there was an effect of education model based on sms gateway based education model on blood sugar levels of diabetics with p-value = 0.002. Conclusions: SMS gateway-based education model affects blood sugar levels of diabetics.
Difference of allergic reaction on hand sanitizer gel and liquid among nurses at RSU Karsa Husada Batu
Authors: Adilah Lilah
Published: June 2023

Introduction: The program to improve the hand hygiene of health workers has been declared by WHO through a patient safety program that sparked the Global Patient Safety Challenge "clean care is safe care". Hand hygiene practice, health workers may use the gel or liquid form of hand sanitizer with alcohol-based ingredients. However, alcohol is flammable, causing dryness and irritation of the skin on repeated use and increases the risk of viral infections that trigger inflammation of the digestive tract. Objectives:  Researcher would like to find any difference on allergic reaction between the use of hand sanitizer gel and liquid form which were commonly used by nurses at RSU Karsa Husada Batu during hand hygiene practice. Methods:  The research design used is a survey research with a cross sectional approach where the researcher observes the research subjects using a check list and questionnaire, with a sample of 80 respondents. The data analysis used non-parametric statistics Mc-Nemar test. Results: The results of the Mc-Nemar Test showed a p value of 0.033 < 0.05 which means that the use of hand sanitizer gel and liquid has a significant difference in the allergic reaction among nurses. Conclusions:  Hand sanitizer in gel or liquid form were safe as long as use correctly and properly, also selecting a type of hand sanitizer must be matched with the individual skin
The relationship between family support and the quality of life of patients with seroconcordant HIV at the Pandian health center and Pamolokan health center, Sumenep Regency
Authors: Fikri, M.Kep Zahid , Arfianto Muhammad Ari , ‘Ibad Muhammad Rosyidul , Kholis Moh. Agung Nur , Mu'jizah Khikmatul , Toonsiri Chanandchidadussadee , Wijaya Ridi Putra Kusuma
Published: June 2023

Introductions: The HIV/AIDS endemic infected millions worldwide in 2019. Indonesia reported a very significant case of the disease, where East Java occupies the fourth position out of all the provinces. People who suffer from this disease (ODHA) are often associated with a poor quality of life. Family support is needed to control the patient's disease and improve the patient's quality of life. Objectives: This study aims to determine the relationship between family support and the quality of life of seroconcordant HIV patients. Methods: The study design used cross-sectional with a sample of 36 seroconcordant PLHIV patients and 32 people who met the inclusion criteria (living with family, married, and registered at the Sumenep District Health Center). The data collection instrument used the "family support" questionnaire and WHOQL-HIV Bref. The collected data were analyzed using the Rank Spearman technique at a significance level of 0.05. Results: The results of this study showed that more than half of the respondents (59.4%) received "good" family support; the majority of respondents (78.1%) have a “fairly good” quality of life; and there is a significant relationship between the two variables as evidenced by the p-value = 0.002 which has a "strong" relationship strength as evidenced by the correlation coefficient = 0.520 and has a unidirectional relationship as evidenced by the positive correlation coefficient. The more family support is improved, the quality of life of the respondents will increase. Conclusion: There is a significant, strong, and one-way relationship between family support and the quality of life of seroconcordant HIV patients. Families should increase their support for HIV patients to improve their quality of life in everyday life.
ANALISIS E-LEARNING READINESS PADA PEMBELAJARAN KIMIA DI SMA NEGERI KOTA BANDA ACEH
Authors: Yulian Muammar , Rahmi Chusnur , Wahyuni Ade Rida
Published: June 2023

The Covid-19 pandemic has changed our activities, including activities in the learning process. Previously, the learning process was carried out directly in the classroom, but the pandemic has changed into online learning such as e-learning. The implementation of e-learning in schools should be followed by an analysis of the level of e-learning readiness (ELR). This study aims to determine the readiness level of State Senior High Schools (SMA Negeri) Banda Aceh, namely SMA Negeri 1, SMA Negeri 3 and SMA Negeri 4. The method used in this study was descriptive qualitative with the number of research subjects as many as 94 students and 2 teachers in each school. The instrument used in this study was a questionnaire compiled and validated based on the Aydin & Tasci ELR model. The results showed that the three schools obtained ELR scores respectively, SMA Negeri 1 () = 3.53, SMA Negeri 3 () = 3.54. The score showed that these schools are ready but need a few improvements in applying e-learning at school. Aspects that must be improved are humans, technology, innovation, and development.
Sistema de liberação controlada de memantina para o tratamento da doença de Alzheimer: revisão integrativa = Memantine controlled release system for the treatment of Alzheimer's disease: integrative review
Authors:   , Medeiros Danielle Cristina Rodrigues , Silva Larissa de Souza
Published: June 2023

A doença de Alzheimer (DA) é uma doença degenerativa multifatorial com alta incidência no Brasil. É responsável por prejuízos sociais e econômicos aos pacientes e seus familiares, sendo a atrofia neuronal e a perda de sinapses suas principais características. Embora os medicamentos atuais possam retardar sua progressão, eles podem causar efeitos adversos e serem difíceis de administrar devido à condição. Este estudo teve como objetivo destacar as tecnologias emergentes no tratamento da DA com liberação modificada de memantina por meio de uma revisão integrativa. Os fatores de inclusão foram artigos científicos localizados em bases de dados específicas com descritores em inglês em periódicos de alto impacto entre 2003 e 2023. Com a adoção desses filtros, foram selecionadas seis publicações originais que utilizavam sistemas de liberação modificada de memantina como ferramentas para otimizar a farmacodinâmica e farmacocinética e melhorar o desempenho na entrega do fármaco ao alvo de ação. Os estudos incluídos nesta revisão estão na fase pré-clínica de desenvolvimento. Assim, pode-se mostrar que há perspectiva de lançamento de novos produtos e sistemas de liberação, como novas vias de administração e dosagens. Igualmente, apesar dos inúmeros fatores que condicionam a adesão ao tratamento, concluiu-se que as formas farmacêuticas de libertação modificada, nomeadamente, solução oral e adesivos transdérmicos e intranasais, podem contribuir positivamente para a adesão ao tratamento farmacológico. Essas tecnologias são ferramentas promissoras para melhorar os medicamentos atuais e futuros, aumentando sua biodisponibilidade, diminuindo efeitos adversos e facilitando a administração de doses em pacientes com diagnóstico de DA.
Fast-slow Atrioventricular Nodal Reentrant Tachycardia Incorporating Superior and Inferolateral Left Atrial Slow Pathways
Authors: MATSUMOTO Kazuhisa , Mori Hitoshi , Nagashima Koichi , Kaneko Yoshiaki , Kato Ritsushi
Published: June 2023

A 70-year-old man revealed a rare type of atrioventricular nodal
reentrant tachycardia (AVNRT) involving distinct retrograde pathways,
Superior Slow Pathway (SSP) and Inferolateral Left Atrial Slow Pathway
(ILA-SP). Radiofrequency ablation was successfully performed on the
non-coronary cusp and in the left atrium, respectively, to eliminate the
tachycardias. Due to the anomalous electrical conduction patterns,
careful diagnosis and ablation strategies were necessary to avoid the
risk of atrioventricular block. These findings underscore the diversity
and complexity of AVNRT and highlight the importance of tailored
therapeutic approaches.
A Nonconformal Nonlocal Approach to Calculating Statistical Spread in Fatigue Indicator Parameters for Polycrystals
Authors: Moore John , Martinez Caitlin , Chandel Ayushi
Published: June 2023

In the study of fatigue fracture in metals, fatigue indicator parameters
(FIPs) are nonlocal quantities that are used to model and predict the
driving force needed to incubate fatigue cracks. These FIP values can be
used to design materials with microstructural features less prone to
fatigue failure. However, the nonlocal nature of fatigue indicator
parameters introduces another unknown variable that must be determined
for accurate predictions: the volume over which nonlocal averages are
performed. Many studies use nonlocal volumes that enclose a
predetermined number of finite elements in a polygranular crystal
plasticity simulation. To encapsulate the entire microstructure, these
nonlocal volumes must be conformal to the microstructure (i.e., they do
not overlap or have gaps between them). Some studies base the length
scale of these nonlocal volumes on constant values or on the size of
relevant microstructural features. It has been shown that if the length
scale is too small, the nonlocal FIP predictions are mesh dependent.
But, if the length scale is too large, the experimentally observed
statistical spread in fatigue life is not captured. This work introduces
a nonconformal nonlocal volume (i.e., a volume that surrounds each
element and overlaps nonlocal volumes). Averaging FIP over this nonlocal
volume both captures the spread in fatigue data and is mesh independent.
It also allows for weighted nonlocal averages that would have excluded
some of the microstructure using the conformal approach. While this
approach is more accurate than the previous approaches, it does require
a large amount of computational resources to determine each nonlocal
volume, so a parallelized algorithm that is scalable across multiple
computing nodes is employed. The example polycrystalline material for
this work is Ti-6Al-4V, a common titanium alloy with a hexagonal
closed-packed crystal structure.
STUDY OF HETEROTIC CROSS COMBINATIONS FOR FRUIT YIELD AND IT’S COMPONENT TRAITS IN OKRA [ Abelmoschus esculentus (L.) Moench]
Authors: Reddy M. Praveen Kumar , Talekar Nilesh
Published: June 2023

The present research study helps in evaluation of F
hybrids for enhancement of the okra production through the selection of
superior heterotic hybrids by L x T design during monsoon-2022. A total
of 48 crosses are developed by crossing in 8 x 6 fashion of lines and
testers along with standard checks Punjab-8 and Punjab-7 were sown in 3
replications in experimental design of Randomized Block Design at
Agricultural research farm in Lovely Professional University, Phagwara,
Punjab for heterosis of fruit yield and its component traits in bhendi.
An observation of fifteen quantitative characters were recorded. The
ANOVA for mean sum of squares is substantial across all the characters
suggests that there is an ample amount of genetic variation present
among parents and hybrids. The fruit yields of GFS GOLD-V4 x IC058768,
VRO-4 x IC048281 and Palm Komal x IC048281 were much higher than those
resulting from standard checks, and they are recommended for additional
evaluation and can be utilized for heterosis commercially.The maximum
positive and substantial heterosis was observed for Height of Plant
(113.22) in Palm Komal x IC048281 and next to it is Nodes per Plant
(77.79) and Fruits per Plant (77.13) in Palm Komal x IC046018. The cross
Palm Komal x IC048281 displaying significant desirable heterobeltiosis
and economic heterosis not only for yield and also characters like
Height of Plant, Fruits per Plant, Nodes per Plant, Average Fruit
weight, Branches per Plant, Fruit girth and Fruit length among top three
cross combinations for component traits which is highly recommended for
commercial okra crop improvement.
A robust decomposed system control for an electro-mechanical linear actuator mechanism under input constraints
Authors: Bahari Mohammad , Shahna Mehdi Heydari , Mattila Jouni
Published: June 2023

This paper aims to develop a robust decomposed system control (RDSC)
strategy under input constraints for an electro-mechanical linear
actuator (EMLA) with model uncertainty and external disturbances. At
first, a state-space model of a complex multi-stage gearbox EMLA system,
driven by a permanent magnet synchronous motor (PMSM), is developed, and
the non-ideal characteristics of the ball screw are presented through
the model. This results in a six-order nonlinear strict-feedback form
(NSFF) system that is decomposed into three subsystems. As the paper’s
main result, a novel RDSC strategy with uniform exponential stability
for controlling subsystem states is presented. This developed controller
avoids the “explosion of complexity” problem associated with
backstepping by treating the time derivative of the virtual control
input as an uncertain system term. The proposed method, while assuming
load disturbances and input constraints with arbitrary bounds, offers a
straightforward control approach for a broader range of applications.
The controller’s performance is evaluated through the simulation of two
distinct duty cycles, each representing different levels of demand on
the actuator facing load disturbances near the rated motor performance.
Comparative Antibacterial Efficacy of Honey and Ciprofloxacin Against Selected Bacterial Pathogens.
Authors: Ada Ada , Amaeze Ngozi , Isa Sa’adatu
Published: June 2023

Since ancient times, honey has been utilised as an alternative treatment
for some clinical diseases. This study investigates the antibacterial
potential of honey extracts obtained from Obanliku Hills in Cross River
State, Nigeria, against Staphylococcus aureus, Pseudomonas aeruginosa,
and Escherichia coli. Honey was extracted using successive solvent
extraction; Methanol, Ethyl acetate and n-Hexane were used as extraction
solvents. The bacteriostatic potential of all three extracts was
determined using well diffusion assay. Methanol and n-hexane extracts
showed no bacteriostatic impact, while the ethyl acetate extract
exhibited concentration-dependent bacteriostatic and bactericidal
effects. A significant (p<0.05) higher inhibition was observed
at 40 mg/ml of the honey extract compared to 10 mg/ml against all three
test organisms. In conclusion, honey extract had a greater bactericidal
effect against Staphylococcus aureus compared to E. coli and P.
aeruginosa.
Simplification of DFT and IDFT in PRACH
Authors: Jiang Yufeng , Kang Shouxin
Published: June 2023

The respective simplifications of prime-point DFT and ultra-long-point
IDFT in PRACH are proposed. The former is an equivalent substitution of
DFT function by using the property of ZC sequence, and the latter is an
approximation based on cubic spline interpolation, which not only
reduces the IDFT points, but also is easy to construct.
Fabrication of a novel double Z-scheme ternary heterostructure photocatalyst of MIL-101(Cr)/Fe3O4-SiO2/nanorod-graphitic carbon nitride for visible-light photocatalytic degradation of oilfield-produced water pollutants
Authors: azmoon parisa , farhadian mehrdad , Pendashteh Alireza , tangestaninejad shahram
Published: June 2023

A novel double Z-scheme ternary heterostructure photocatalyst of
MIL-101(Cr)/Fe3O4-SiO2/nanorod-graphitic carbon nitride
(MIL-Cr/F@S/nr-GCN) was fabricated via the hydrothermal method.
Physicochemical properties of photocatalysts were measured by XRD, FTIR,
FESEM, EDX, TEM, BET, PL, and UV-vis DRS analysis. The adsorption and
photodegradation of oilfield-produced water (O-PW) pollutants were
investigated by synthesized photocatalysts. The ternary heterostructure
composite containing 20 wt% of nr-GCN showed remarkable photocatalytic
performance than nr-GCN and MIL-Cr/F@S binary composite. The maximum
chemical oxygen demond (COD) removal efficiency of synthetic
oilfield-produced water obtained 97.4% under visible-light illumination
at optimum conditions (pH 4, illumination time 90 min, photocatalyst
dosage 0.6 g/L, and pollutant initial concentration 754 mg/L). Also,
total petroleum hydrocarbons (TPHs) were removed 98% at these
conditions. The kinetic and isotherm adsorption study revealed that the
O-PW adsorption process obeyed the pseudo-second-order kinetic and
Freundlich isotherm models. The degradations rate of O-PW by ternary
composite is 2.8 times, and 2 times higher than the nr-GCN, and
MIL-Cr/F@S, respectively. The high specific surface area (653 m2/g),
appropriate bandgap energy (1.6 eV), and the good charge carrier
separation based on the double Z-scheme caused the enhancement of
photocatalytic activity. The ternary photocatalysts exhibited high
reusability after 5 cycles without leaching Cr ions into the treated
water. The results confirmed that the new ternary heterostructure is a
green and robust photocatalyst in treatment of oilfield-produced water.
Deep Learning Method to Find Swanepoel Envelopes in Transmission Spectroscopy
Authors: Matito Manuel Ballester , Ballester Manuel , Marquez Emilio , Marquez Almudena P , Lopez-Tapia Santiago , Cossairt Oliver , Willomitzer Florian , Katsaggelos Aggelos K
Published: June 2023

This research presents a novel Deep Learning method to find the Swanepoel Envelopes from the transmission spectra of dielectric thin films. This method improves the efficiency and accuracy of the film’s optical characterization.
Global landscape of lysine succinylome in Saccharopolyspora erythraea
Authors: Ke Xiang , jiang xing , Tian Xiwei , chu ju
Published: June 2023

As a novel protein post-translational modification, lysine succinylation
is widely involved in metabolism regulation. In this study, we focused
on the distribution of lysine succinylation sites and their
physiological functions in Saccharopolyspora erythraea. Using
high-resolution 4D label free mass spectrometry, a large and global
protein succinylome was identified in a hypersuccinylated strain
E3ΔsucC. The results showed that succinylated proteins are predominantly
involved in protein synthesis-related pathways (e.g., ribosomes, tRNA)
and metabolic pathways, such as the TCA cycle. Proteins in these
pathways generally have a higher lysine content, suggesting that lysine
succinylation may have a greater regulatory role in biochemical
reactions involving acidic substrates. Motif analysis revealed that
charged amino acids (D, E, K, R and W) display a more regular
distribution around acylation sites, implying that the polar effect
between residues may be the key factor influencing lysine succinylation.
Based on predicted protein structures, we highlighted the potential
impact of lysine succinylation on enzyme activity in the TCA cycle. In
conclusion, this study offers valuable insights into the regulation of
lysine succinylation and contributes to a comprehensive understanding of
its physiological functions in actinomyces.