bluuebunny/crossref_metadata_2025 huggingface dataset:
Spider Matrix: Towards Research Paper Evaluation and Innovation for Everyone
Authors: XU Yanheng , Ye Shuqian , Liu Rulin , Shao Ling , Zhu Xi
Published: April 2024

This study investigates the transformative effects of Artificial Intelligence (AI) on academic publishing, emphasizing the innovative Spider Matrix system. Designed for public use, this platform enables users to assess research papers and identify groundbreaking aspects. It addresses the challenges posed by the growing volume of publications and the imperative to uphold quality in scholarly communication. The paper highlights AI's pivotal role in enhancing the peer-review process. Through the Spider Matrix case study, the paper demonstrates AI's utility in appraising academic papers and patents across various dimensions, such as originality, robustness, and impact. This system goes beyond conventional metrics like citation counts, offering prompt, equitable evaluations grounded in the intrinsic quality of each work. Its adaptability to different academic fields and patent analysis underscores its versatility and efficacy in providing a more equitable and comprehensive framework for scholarly assessment. Additionally, the system is noted for its ability to generate innovative ideas from significant evaluation results. This paper emphasizes AI's potential to revolutionize academic guidance, publishing, and the generation of innovative ideas, aligning with the growing need for more meaningful and substantial research impact metrics. Ultimately, this leads to higher quality research outputs.
Interfacial Carbonyl Groups of Propylene Carbonate and Diethyl Sebacate Facilitate the Reversible Binding of Nitrogen Dioxide
Authors: Clark Jessica , Allen Heather
Published: April 2024

The interaction of NO2 with organic interfaces is critical in the development of NO2 sensing and trapping technologies, and equally so to the atmospheric processing of marine and continental aerosol. Recent studies point to the importance of surface oxygen groups in these systems, however the role of specific functional groups on the microscopic level has yet to be fully established. In the present study, we aim to provide fundamental information on the behavior of NO2 at atmospherically relevant organic interfaces that may also help inform innovation in NO2 sensing and trapping development. We then present an investigation into the structural changes induced by NO2 at the surface of propylene carbonate (PC), an environmentally relevant carbonate ester. Surface-sensitive spectra of the PC liquid surface are acquired before, during, and after exposure to NO2 using infrared reflection-absorption spectroscopy (IRRAS). Spectra reveal that NO2 preferentially interacts with the carbonyl of PC at the interface, forming a distribution of binding symmetries. At low ppm levels, NO2 saturates the PC surface within 10 minutes and the perturbations to the surface are constant over time during the flow of NO2. Upon removal of NO2 flow, and under atmospheric pressures, these interactions are reversible, and the liquid surface structure of PC recovers completely within 30 min. Another ester-containing molecule, diethyl sebacate (DES), was also investigated and the same carbonyl-specific interaction with NO2 was intermittently observed.
Learning Force Field Parameters from Differentiable Particle-Field Molecular Dynamics
Authors: Carrer Manuel , Cezar Henrique Musseli , Bore Sigbjørn Løland , Ledum Morten , Cascella Michele
Published: April 2024

We develop ∂-HylleraasMD (∂-HyMD), a fully end-to-end differentiable molecular dynamics software based on the Hamiltonian hybrid particle-field formalism, and use it to establish a protocol for automated optimization of force field parameters. ∂-HyMD is templated on the recently established HylleraaasMD software, while using the JAX autodiff framework as the main engine for the differentiable dynamics. ∂-HyMD exploits an embarrassingly parallel optimization algorithm by spawning independent simulations, whose trajectories are simultaneously processed by reverse mode automatic differentiation to calculate the gradient of the loss function, which is in turn used for iterative optimization of the force-field parameters. We show that parallel organization facilitates the convergence of the minimization procedure, avoiding the known memory and numerical stability issues of differentiable molecular dynamics approaches. We showcase the effectiveness of our implementation by producing a library of force field parameters for standard phospholipids, with either zwitterionic or anionic heads, and with saturated or unsaturated tails. Compared to the all-atom reference, the force field obtained by ∂-HyMD yields better density profiles than the parameters derived from previously utilized gradient-free optimization procedures. Moreover, ∂-HyMD models can predict with good accuracy properties not included in the learning objective, such as lateral pressure profiles, and are transferable to other systems, including triglycerides.
Correlation Analysis in X-ray Photoemission Spectroscopy
Authors: Bhatt Prajna , Liu Yuhan , Isaacs Mark , Palgrave Robert
Published: April 2024

X-ray photoelectron spectroscopy (XPS) is a powerful technique for surface analysis, but such analysis can be hindered by uncertainty in modelling spectra. Often, many spectral models have a similar goodness of fit, and distinguishing between them can be impossible without additional information. A further challenge is found in interpreting spectra from samples consisting of multiple chemical compounds. We show here how correlation analysis can be used to interpret large XPS datasets. Correlations in atomic concentrations and binding energies of core lines can be interpreted within a framework of an underlying chemical model and this can yield additional information compared with analysis of each spectrum individually. We give examples of the usage of this analysis on some simple systems, and discuss the potential and limitations of the technique.
Pyridine-Boryl Radical-Catalyzed [3π + 2σ] Cycloaddition for the Synthesis of Pyridine Bioisosteres
Authors: Wang Honggen , Liu Yuan , Lin Shuang , Ding Zhengwei , Li Yin , Tang Ya-Jie , Xue Jiang-Hao , Li Qingjiang , Li Pengfei
Published: April 2024

The exploration of C(sp3)-rich three-dimensional (3D) scaffolds as bioisosteres for planar aromatics has garnered increasing attention. While the bioisosterism of benzenes has been extensively studied, the bioisosterism of pyridines, the second most prevalent aromatic compounds in pharmaceuticals, faces additional challenges and has encountered surprisingly limited success. In this study, we propose unprecedented 2-azabicyclo[3.1.1]heptenes as effective bioisosteres of 1,3,5-trisubstituted pyridines in terms of not only 3D conformation but also basicity. We develop a pyridine-boryl radical-catalyzed [3π + 2σ] cycloaddition reaction of vinyl azides with bicyclo[1.1.0]butanes (BCBs) as an efficient synthetic approach. Synthetic manipulation of the products reveals valuable synthetic handles, allowing for the modular synthesis of various pyridine bioisosteres.
Extrusion of MOF-Polymer Nanocomposites with High MOF Loadings
Authors: Powell Joshua A , Marquez Jazmine Aiya D , Johnson Giles A , Ozdemir Ray O K , Wang Qingsheng
Published: April 2024

While metal-organic frameworks (MOFs) hold great promise for a wide range of industrial applications, the challenges of handling fine crystalline powders have limited their adoption. MOF-polymer composites are one solution to this challenge, as composites or membranes are substantially easier to handle, however most existing MOF-polymer composites have low MOF loadings and suffer MOF leaching due to the weak interactions between the MOF and the polymer. In this work, we report the continuous extrusion of MOF-polymer composites containing up to 60 wt% of commercially available MOFs and successful extrusion of small amounts composites containing 70 wt% MOF, with the composite viscosity an important factor in the success of the extrusion. The MOF is well-distributed through the composite and remains crystalline despite the high temperatures and mechanical forces involved in the extrusion process. While the composites are more brittle than the base polymer and appear largely non-porous, the suspected presence of inaccessible internal pores coupled with the increased thermal stability of the composites compared to the base polymer indicate potential for the composites to be used as fire resistant materials.
Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome
Authors: LeBleu Valerie S , Kanasaki Keizo , Lovisa Sara , Alge Joseph L , Kim Jiha , Chen Yang , Teng Yingqi , Gerami-Naini Behzad , Sugimoto Hikaru , Kato Noritoshi , Revuelta Ignacio , Grau Nicole , Sleeman Jonathan P , Taduri Gangadhar , Kizu Akane , Rafii Shahin , Hochedlinger Konrad , Quaggin Susan E , Kalluri Raghu
Published: April 2024

Glomerular filtration relies on the type IV collagen (ColIV) network of the glomerular basement membrane, namely, in the triple helical molecules containing the α3, α4, and α5 chains of ColIV. Loss of function mutations in the genes encoding these chains (Col4a3,Col4a4, andCol4a5) is associated with the loss of renal function observed in Alport syndrome (AS). Precise understanding of the cellular basis for the patho-mechanism remains unknown and a specific therapy for this disease does not currently exist. Here, we generated a novel allele for the conditional deletion ofCol4a3in different glomerular cell types in mice. We found that podocytes specifically generate α3 chains in the developing glomerular basement membrane, and that its absence is sufficient to impair glomerular filtration as seen in AS. Next, we show that horizontal gene transfer, enhanced by TGFβ1 and using allogenic bone marrow–derived mesenchymal stem cells and induced pluripotent stem cells, rescuesCol4a3expression and revive kidney function in Col4a3-deficient AS mice. Our proof-of-concept study supports that horizontal gene transfer such as cell fusion enables cell-based therapy in Alport syndrome.
Contribuições das dimensões psicológicas para a gestão ambiental em uma indústria de jeans: um estudo de caso
Authors: Wachholz Larissa Aparecida , Grossi-Milani Rute , Lizama Maria de los Angeles Perez
Published: April 2024

Com o intuito de reduzir os impactos gerados pela produção de jeans, surgem estratégias de gestão ambiental nas indústrias, as quais necessitam da sensibilização dos trabalhadores. Evidencia-se, dessa forma, a psicologia ambiental que oferece instrumentos para análise das relações pessoa-ambiente, auxiliando no processo de conscientização ambiental. Diante disso, este estudo objetivou analisar o comportamento e as crenças ambientais dos trabalhadores de uma indústria de jeans para, assim, apresentar perspectivas de efetivação da gestão ambiental nas atividades da empresa. A indústria, objeto deste estudo, atua no segmento Private Label, produzindo um volume de aproximadamente 300.000 peças por mês. Além disso, possui estratégias para mitigar os impactos ambientais e algumas certificações de responsabilidade socioambiental. Para a coleta de dados, foram utilizados como instrumentos: entrevista semiestruturada com a gestora; análise dos documentos fornecidos pela empresa; e aplicação das Escalas de Comportamento Ecológico e de Crenças Ambientais aos colaboradores da organização. Os resultados indicam que apesar de a indústria propor diversas estratégias sustentáveis, os participantes da pesquisa não participam efetivamente dessas ações e possuem poucos comportamentos relacionados ao ativismo e consumo. Portanto, sugere-se uma proposta de gestão ambiental que inclua a análise da percepção geral dos colaboradores da empresa, um programa de educação ambiental, estratégias de Produção Mais Limpa e a divulgação das práticas.
Investigar la moda indígena en Abya Yala
Authors: Beltrán-Rubio Laura
Published: April 2024

Este ensayo ofrece una aproximación metodológica para la investigación de la moda indígena en Abya Yala, con base en los aprendizajes que han ofrecido investigaciones recientes sobre las artes indígenas norteamericanas. Dichas metodologías deben estar enraizadas en los sistemas de pensamiento, las formas de investigación y las cosmovisiones propias de las culturas indígenas. El carácter relacional de los sistemas de conocimiento indígenas permite la co-existencia de múltiples verdades y se aceptan como autoridades a personas y objetos indígenas que han sido tradicionalmente excluidos de la construcción del conocimiento académico occidental. Este ensayo propone centrar la investigación de la moda indígena en los paradigmas nativos para reescribir las narrativas hegemónicas, dando protagonismo a las personas, los objetos y las cosmovisiones indígenas.
Yawanawá: o encontro com o Design de Moda e a globalização
Authors: Couto Mariana dos Santos , Cardoso Fernanda de Abreu
Published: April 2024

Este artigo apresenta uma discussão teórica e uma análise crítica da relação do povo indígena amazonense Yawanawá com a globalização nos âmbitos político, social e econômico. Além disso, explora o diálogo estabelecido entre o povo indígena e o Design de Moda, com foco específico na colaboração com a marca carioca FARM, e as implicações reveladas por essa conexão. Como referencial teórico são empregados os autores Néstor García Canclini, Renato Ortiz e Alberto Cipiniuk, além de ser realizada uma análise de produtos da parceria, como esta é apresentada e a observação in loco de uma das lojas internacionais da marca. Buscamos investigar a dinâmica dessa relação para examinar a questão da representação de identidade nacional e “brasilidade” enquanto construção e valor de diferenciação em um produto de moda, bem como o poder discursivo de uma marca em processo de internacionalização. Por meio dessa pesquisa, procuramos compreender como o povo Yawanawá se posiciona diante dos desafios impostos pela globalização, abordando os impactos sociais e econômicos que essa relação com o mundo globalizado gera, assim como investigamos como uma marca se utiliza dessa relação para gerar visibilidade, demonstrar responsabilidade social em seu discurso e seu posicionamento. Ao considerar esses aspectos, o artigo pretende lançar luz sobre as complexidades dessa relação e suas possíveis implicações para a identidade cultural da etnia Yawanawá e o poder discursivo da marca de moda FARM em um cenário globalizado.
Tissue Flossing: A Commentary on Clinical Practice Recommendations
Authors: Cheatham Scott W. , Baker Rusty
Published: April 2024

Tissue flossing is an emerging myofascial intervention used by sports medicine professionals with a growing body of research evidence. Sports medicine professionals may use tissue flossing to increase myofascial mobility, improve joint ROM, enhance athletic performance, and reduce pain. Despite the increasing use, there is no consensus on clinical practice recommendations for this intervention. The purpose of this commentary is to discuss proposed clinical practice recommendations for tissue flossing and to encourage sports medicine professionals and researchers to contribute their expertise to further develop best practices.

Level of Evidence

5
A Biomechanical Review of the Squat Exercise: Implications for Clinical Practice
Authors: Straub Rachel K , Powers Christopher M
Published: April 2024

The squat is one of the most frequently prescribed exercises in the rehabilitative setting. Performance of the squat can be modified by changing parameters such as stance width, foot rotation, trunk position, tibia position, and depth. An understanding of how the various squatting techniques can influence joint loading and muscular demands is important for the proper prescription of this exercise for various clinical conditions. The purpose of this clinical commentary is to discuss how the biomechanical demands of the squat can be influenced by various modifiable parameters. General recommendations for specific clinical conditions are presented.

Level of Evidence

5
Establishing Normal Variances and Expectations for Quadriceps Limb Symmetry Index Benchmarks Based on Time from Surgery After Anterior Cruciate Ligament Reconstruction.
Authors: Hazzard Sean , Connolly Saoirse , Wiater Ashley , Sprague Isabella , Doolan-Roy Emily , Lampros Rachel , Asnis Peter D
Published: April 2024

The anticipated timeline for muscle strength as well as return to running and sports are some of the most common inquiries by patients undergoing anterior cruciate ligament reconstruction. Despite the popularity of this procedure, the answers to these inquiries are not well described in the literature. The purpose of this study was to evaluate the range of quadriceps strength percentage and function benchmarks at various points after anterior cruciate ligament reconstruction surgery based on sex, age, and graft.

Design

Observational Cohort Study

Methods

Patients who underwent anterior cruciate ligament reconstruction (ACLR) were evaluated at various points after their surgery with handheld dynamometer assessments. Additional hop and balance testing was performed and patients were evaluated for clearance for running and sport via a physical therapist directed functional movement assessment (FMA). The progression of quadriceps symmetry throughout the postoperative period was examined with multi-level models, estimates of time to reach 70%, 80%, and 90% quadriceps symmetry were obtained from the fitted model.

Results

A total of 164 patients were evaluated. Patients either received bone-tendon-bone (BTB) autograft (n=118) or BTB allograft (n=46) for their ACL graft. Average age was 31.1 years-of-age (SD: 13.6). Males undergoing ACLR using BTB autograft (n=53) were able to achieve 80% quadriceps symmetry earlier than females (n=65) (5.7 months vs 7.1 months), were cleared to return to run sooner (5.6 months vs 6.8 months) and passed an FMA exam earlier (8.5 months vs 10 months). Males undergoing ACLR with allograft (n=13) were able to achieve 80% quadriceps symmetry earlier than females (n=33) (3.9 months vs 5.4 months) and were cleared to run sooner (4.5 months vs 5.8 months).

Conclusion

Patients undergoing BTB autograft obtain 80% quadriceps symmetry at an average of 5.7 months for males and 7.1 months for females. Individuals under the age of 25 obtain their quadriceps symmetry faster and are cleared to return to running faster than individuals over 25. Male sex is associated with decreased amount of time to obtain clearance for running and for full activity. Male sex is associated with decreased amount of time to regain quadriceps symmetry however this was not significant.

Level of Evidence

4 (Case series)
Validity and Responsiveness of a Modified Balance Error Scoring System Assessment Using a Mobile Device Application in Patients Recovering from Ankle Sprain
Authors: Crowell Michael S , Thomasma Eliot , Florkiewicz Erin , Brindle Richard , Roach Megan , Goss Donald , Pitt Will
Published: April 2024

Background

Static balance is often impaired in patients after ankle sprains. The ability to identify static balance impairments is dependent on an effective balance assessment tool. The Sway Balance Mobile Application (SWAY App) (Sway Medical, Tulsa, OK) uses a smart phone or tablet to assess postural sway during a modified Balance Error Scoring System (mBESS) assessment and shows promise as an accessible method to quantify changes in static balance after injury.

Purpose

The primary purposes of this study were to determine the ability to differentiate between those with ankle sprain versus controls (construct validity) and ability to detect change over time (responsiveness) of a mBESS assessment using a mobile device application to evaluate static balance after an acute ankle sprain.

Study Design

Case-control study.

Methods

Twenty-two military academy Cadets with an acute ankle sprain and 20 healthy Cadets were enrolled in the study. All participants completed an assessment measuring self-reported function, ankle dorsiflexion range of motion (via the weightbearing lunge), dynamic balance, and static balance. Static balance measured with the mBESS using the SWAY App was validated against laboratory-based measures. Cadets with ankle sprains completed their assessment twice: once within two weeks of injury (baseline) and again after four weeks of rehabilitation that included balance training. Independent and paired t-tests were utilized to analyze differences over time and between groups. Effect sizes were calculated and relationships explored using Pearson’s correlation coefficients.

Results

The mBESS scores measured by the SWAY App were lower in participants with acute ankle sprains than healthy Cadets (t = 3.15, p = 0.004). Injured participants improved their mBESS score measured by SWAY at four weeks following their initial assessments (t = 3.31, p = 0.004; Baseline: 74.2 +/- 16.1, 4-weeks: 82.7 +/- 9.5). The mBESS measured by the SWAY App demonstrated moderate to good correlation with a laboratory measure of static balance (r = -0.59, p < 0.001).

Conclusion

The mBESS assessed with a mobile device application is a valid and responsive clinical tool for evaluating static balance. The tool demonstrated construct (known groups) validity detecting balance differences between a healthy and injured group, concurrent validity demonstrating moderate to good correlation with established laboratory measures, and responsiveness to changes in static balance in military Cadets during recovery from an acute ankle sprain.

Level of Evidence

Level 3
Isokinetic Testing: Why it is More Important Today than Ever
Authors: Wilk Kevin E , Arrigo Christopher A , Davies George J
Published: April 2024

Isokinetics is a proven method to train and objectively assess the capability of muscle groups, particularly at the knee. The current re-injury rates and less than optimal return to sport percentages seen following anterior cruciate ligament surgery highlights the need for greater focus on what tests and methods are used to make these critical decisions. Isokinetics remains the best single method to objectively determine dynamic muscle strength, power, rate of force development and endurance. These factors make it well-suited to play a crucial role in influencing the appropriate patient progression through a rehabilitation program and assisting in determining return to play readiness following injury or surgery. In this article we will discuss why we believe isokinetics is a useful and necessary testing method, and elucidate testing parameters and goals used during knee extension/flexion assessment.
Securing healthcare data in smart cities: A machine learning approach
Authors: Anchugam  , Jayanthila Devi
Published: April 2024

Artificial intelligence has a variety of applications in the healthcare sector due to its capacity to assist in not only treatment and especially operations, but also diagnostics and prevention. There is hardly any industry that does not benefit from an increase in IT resources and self-learning computer networks. This paper presents smart healthcare data which can assess the situation and determine whether or not a person requires immediate medical assistance, as well as whether or not their symptoms will likely improve on their own over time. In addition to its contributions to treatment, operations, diagnostics, and prevention, Artificial Intelligence (AI) plays a pivotal role in optimizing healthcare processes and resource utilization. The integration of AI technologies in the healthcare sector has facilitated enhanced data analysis, personalized treatment plans, and more efficient allocation of medical resources. The intelligent processing of vast amounts of patient data enables timely identification of emerging health trends and the development of targeted interventions. Moreover, AI-powered healthcare data systems have the potential to revolutionize patient care by providing real-time assessments of individual health statuses. These systems can not only discern the need for immediate medical assistance but also predict the likelihood of symptom improvement over time, aiding in the formulation of proactive and preventive healthcare strategies. The ongoing advancements in AI continue to refine these capabilities, fostering a future where technology and healthcare seamlessly converge for the betterment of patient outcomes and overall public health.
Best Social Entrepreneurship Teaching and Learning Strategies for Promoting Students' Social Entrepreneurial Minds: A Scoping Review
Authors: Ab Wahid Hariyaty , Abdul Rahman Rafiduraida , Mustaffa Wan Salmuni Wan , Ahmad Noor Lela , Ramdan Mohamad Rohieszan , Muslimat Ade Mufrodi
Published: April 2024

This paper aims to explore the best teaching and learning strategies for promoting students' social entrepreneurial minds. At the initial stage, the scoping review draws from 198 secondary data from various works in the social entrepreneurship education context, including studies on education programs, curricular development, knowledge-acquiring mechanisms, and social entrepreneurial exploration processes. It also examines instructional methods and strategies that foster the development of potential social entrepreneur mindsets. Finally, 26 included papers present a Top-Down and Bottom-Up Approach, Experiential Learning, Action Learning, Community-Based Project, and Problem-Based Learning (PBL) as effective social entrepreneurship teaching and learning approaches to promote social entrepreneurial mindsets. The review concludes that a combination of all of the aforementioned teaching and learning strategies is among the top teaching approaches for effective social entrepreneurship education. The paper proposes that dynamic social entrepreneurship curricula and learning models that emphasize hands-on experience and experience-based learning can be effective strategies for promoting students' social entrepreneurial minds.
Harnessing Artificial Intelligence for Advancing Sustainable Development Goals in South Africa's Higher Education System: A Qualitative Study
Authors: Opesemowo Oluwaseyi Aina Gbolade , Adekomaya Victoria
Published: April 2024

Artificial intelligence (AI) presents opportunities in transforming higher education system and contribute significantly to achieving Sustainable Development Goals (SDGs). This study seeks to leverage AI technologies to advance SDGs within South Africa’s higher education system. It examines AI technology adoption in South African higher education institutions and challenges, strategies, and potential future directions. This qualitative research employed the constructivist principle to unravel the dynamics of AI in advancing SDGs in South Africa. Lecturers from the Department of Information Sciences were the participants of the study. The participants were purposefully selected based on their experience and knowledge of AI technologies. In-depth interview and focused group discussion was employed to generate and estimate responses using thematic content analysis. The result revealed that participants used AI technology to increase students' learning and engagement so students would not doze in class. It was discovered that AI technology has increased the chances for collective learning. The study further proved that AI technology can improve personalized learning experiences of students with diverse learning styles and abilities. This has led to a more inclusive and interactive classroom environment where students feel more motivated and supported in their learning journey. Integrating AI technology into education has shown promising results in improving student outcomes and fostering a more collaborative learning atmosphere. Based on the results, it implies that harnessing AI would advance SDGs in South Africa’s higher education institutions. As such, we recommended that the South African government should formulate comprehensive national AI education policy guidelines for higher education to regulate and harmonize the usage of AI in the higher education system.
Desenvolvimento de curativo biopolímero aditivo cicatrizante com Aloe vera
Authors:   Centro Universitário Teresa D'Ávila - UNIFATEA, Ligabo Jr. Neir , Silva José Wilson de Jesus ,   Centro Universitário Teresa D'Ávila - UNIFATEA, Ribeiro Rosinei Batista ,   CEETEPS - Undidade de Pós-Graduação, Extensão e Pesquisa, Silva Danilo Corrêa ,   Universidade da Região de Joinville - UNIVILLE
Published: April 2024

Com o avanço tecnológico, há a necessidade do desenvolvimento de produtos alternativos mais acessíveis às pessoas, utilizando processos de produção que respeitem o meio ambiente, ao mesmo tempo estabeleçam técnicas inovadoras e mais econômicas, tornando os métodos de produção mais baratos. A seleção de materiais renováveis biopoliméricos, tais como: carboidratos, lipídios e proteínas para manufatura de insumos farmacêuticos com uso em tratamentos curativos é muito promissora, pois possibilita o incremento de curativos bioativos. O tratamento para feridas crônicas demanda muito tempo e recursos, além do mais, expõe o paciente a grandes riscos de complicações, como amputações de membros inferiores em pacientes diabéticos, podendo levar a infecções secundárias graves por resistência a antibióticos e até ao óbito. O curativo, para ser considerado biocompatível, deve possuir determinadas características essenciais, tais como, preservar umedecido o leito da ferida, remover exsudato, proteger o ferimento da ação de micro-organismos patogênicos e não causar reações alérgicas ao paciente. Existem registros desde a pré-história da utilização de plantas medicinais no tratamento de doenças por meio de poções que continham extratos vegetais com finalidade terapêutica. O uso do extrato de Aloe vera, no tratamento de feridas, possibilita mais oxigenação da lesão, aumenta a vascularização e a quantidade de colágeno, que é uma proteína essencial à regeneração tecidual, a fim de que ocorra a cicatrização, em que o tecido é desinflamado e remodelado, promovendo maior multiplicação de células da pele. Este estudo tem como objetivo utilizar o design, de acordo com Baxter, nos processos de desenvolvimento de produtos, para elaborar material biopolimérico, aditivado com extrato glicólico de Aloe vera e que será aplicado no desenvolvimento de um curativo bioativo para tratamento de feridas crônicas e realizar um estudo experimental pelo modelo PERMATUS do produto desenvolvido da cobertura curativa.
Penerapan Teknik Restrukturisasi Kognitif untuk Mengatasi Persepsi Negatif Siswa SDN Purwodadi I
Authors: Wijayanti Heffilia , Saman Abdul
Published: April 2024

Siswa ketika berada di sekolah sering mengalami masalah. Masalah yang dialami juga cukup beragam, mulai masalah pribadi, sosial, belajar maupun karir. Dengan adanya permasalahan-permasalahan tersebut membuat siswa merasa terganggu dan tidak nyaman bahkan mempengaruhi nilai serta kegiatan belajarnya di sekolah. Beberapa siswa mengalami permasalah berkaitan dengan persepsi-persepsi negatifnya terhadap sesuatu hal, baik itu terhadap guru maupun persepsi negatif terhadap temannya, sehingga membuatnya terganggu dan menimbulkan penurunan nilai dibeberapa mata pelajaran. Dengan adanya masalah tersebut, konselor memberikan layanan konseling individu dengan pendekatan Cognitive Behavior Therapy dengan teknik restrukturisasi kognitif. Untuk teknik restrukturisasi kognitif ini terdiri dari enam tahapan, diantaranya: tahap rasional, identifikasi pikiran konseli, pengenalan dan latihan coping thought, peralihan dari pikiran-pikiran negatif ke coping thought, pengenalan dan latihan penguatan positif, serta yang terakhir tugas rumah dan tindak lanjut. Dengan penerapan teknik ini, dapat merubah pemikirian atau persepsi negatif siswa menjadi lebih positif. Hal ini terjadi pada siklus 1, siklus 2, dan juga siklus 3 dimana siswa mampu mengubah persepsi negatifnya menjadi lebih positif.
Upaya Mengurangi Stres Akademik Siswa SMAN 2 Telukjambe Timur Melaui Konseling Individu Pendekatan Rational-Emotive Behavior Therapy
Authors: Permana Hendra Jaya , Latif Suciani , Mannenni Rosmini
Published: April 2024

Salah satu penyebab terjadinya stres akademik yakni disebakan faktor keyakinan irasional individu yang kecenderungannya memberikan dampak secara fisik,  emosi, intelektual atau interpersonal. Oleh karena itu, individu perlu mendapatkan strategi alternatif untuk membantu individu mengatasi masalah tersebut. Penelitian ini bertujuan menerapkan konseling individu melalui pendekatan REBT untuk mengurangi stres akademik siswa kelas XII SMAN 2 Telukjambe Timur. Penelitian ini menggunakan rancangan pre-experimental design dengan bentuk one-group pre-test and post-test design dan pemilihan subjek penelitian dengan menggunakan simple matching. Teknik pengumpulan data berupa angket stres akademik dengan jumlah subjek penelitian 5 siswa yang termasuk kategori tinggi pada skor stres akademik. Berdasarkan hasil perhitungan mean terdapat penurunan skor stres akademik yakni mean Pre-tes sebesar 212,6 dan mean Post-test sebesar 186,5 sehingga menunjukkan selisih penurunan skor sebesar 26. Analisis data menggunakan statistik non-parametrik uji wilcoxson dengan menggunakan bantuan SPSS versi 24 dan hasil asymp.Sig. (1-tailed) menunjukkan sebesar 0,022. Apabila mengacu pada ketetapan α (taraf kesalahan) sebesar 5% maka hasil menunjukkan bahwa 0,022 < 0,05 sehingga dapat ditarik kesimpulan bahwa Ho ditolak dan Ha diterima. Jadi, berdasarkan hipotesis dalam penelitian ini dapat disimpulkan bahwa konseling individu pendekatan rational- emotive behavior therapy dapat mengurangi stres akademik siswa kelas XII SMAN 2 Telukjambe Timur.
Penggunaan Konseling Individu Rational Emotive Behavior Therapy dalam Mengatasi Rendahnya Motivasi Belajar Siswa di SMP Negeri 1 Pulosari
Authors: Pratama Rian Ardi , Latif Suciani , Rosmini Rosmini , Alamsyah Muhammad Nur
Published: April 2024

Terdapat banyak teknik yang dapat digunakan dalam pelaksanaan konseling individu. Penelitian ini bertujuan untuk mendeskripsikan penggunaan pendekatan rational emotive behavior therapy (REBT) dengan metode permodelan  yang diterapkan pada konseli yang memiliki permasalahan motivasi belajar yang rendah pada konseli di SMP Negeri 1 Pulosari. Pada penelitian ini digunakan pendekatan kualitatif dengan jenis kualitatif deskriptif. Simpulan dari penelitian ini yaitu konseli mampu merubah pola pikirnya yang selama ini menjadi permasalahan sehingga menurunkan motivasi belajarnya menjadi lebih baik dan berusaha untuk memperbaiki kesalahannya selama ini sehingga konseli dapat mengikuti kegiatan belajar secara normal kembali.
Konseling Motivational Interviewing dan Cognitive Behaviour Dalam Upaya Rehabilitasi Penyalahguna Narkoba Pada Remaja
Authors: Nuha Moch. Syihabudin , Rofiq Arif Ainur
Published: April 2024

This study discusses efforts to rehabilitate drug abusers using Motivational Interviewing counseling and Cognitive Behavior Therapy.  This research uses qualitative research methods with a case study approach. The research was conducted at the Pratama Clinic of BNN, East Java Province. The subjects in this study were two teenagers with different backgrounds and participated in narcotics counseling at the BNN Pratama Clinic in East Java Province. Data collection was carried out by observation, interviews and providing pre-test and post-test questionnaires. It was shown that before administering the intervention got a score of 11.3 and 11.7. Then after the intervention administration got a score of 12.7 and 12.8, meaning that Motivational Interviewing Counseling and Cognitive Behaviour Therapy can be applied in efforts to rehabilitate drug abusers in adolescents.
Assessment of Residential Satisfaction using Gap Analysis: A Case Study in Naypyitaw City, Myanmar
Authors: Phyu Pan Ei , Effendi Nursyirwan , Purnawan Purnawan
Published: April 2024

This research paper conducts an evaluation of residential satisfaction within government-provided four-storied apartment complexes situated in civil-servant housing areas in Naypyitaw City, Myanmar. As the construction of these apartment buildings continues to address the housing demands of civil servants, comprehending the determinants of residents' contentment becomes paramount. The study encompasses data collected from 500 households through structured questionnaires employing a multi-cluster sampling approach. These questionnaires utilize a five-point Likert Scale format to gauge residents' levels of importance and satisfaction. Gap Analysis is employed to scrutinize the gathered data, ultimately identifying seven pivotal attributes that hold the potential to substantially enhance residential satisfaction. These attributes encompass ceiling height, apartment layout plan, room and corridor dimensions, quantity of rooms, staircase design, neighborhood relations, and proximity to police stations. Based on these revelations, recommendations are tendered, advocating the modification and reevaluation of these attributes in forthcoming housing developments. This underscores the imperative need for creating a livable city by ensuring the provision of essential services in closed proximity to residential areas.
Development of Obstacle Odyssey, an Interactive Game by Using GDevelop
Authors: Panjaitan Cherlina Helena Purnamasari , Retno Sujacka , Hasdyna Novia
Published: April 2024

Games are a medium that is in great demand by almost all ages, including children, teenagers and adults. As game technology develops which can be found on various platforms, games are not just mere entertainment but can also be given educational value in them. The Obstacle Odyssey game was built by applying educational values which are expected to improve the players' abilities in terms of tactical thinking. This Obstacle Odyssey game is an Arcade genre game. This game was built using Gdevelop using a no-code event system.
Classification of Heart Disease Using Modified K-Nearest Neighbor (MKNN) Method
Authors: Lubis Aulia Azzahra Ma'aruf , Dinata Rozzi Kesuma , Aidilof Hafizh Al Kautsar
Published: April 2024

Penyakit jantung memiliki banyak jenis dan gejala yang dialami. Penyakit jantung adalah sebuah kondisi ketika organ jantung tidak dapat bekerja sebagaimana fungsinya dengan baik. Jantung adalah organ penting dalam tubuh manusia yang dimana fungsinya adalah memompa darah ke seluruh tubuh. Karena itu dibutuhkannya diagnosa awal untuk pencegahan penyakit jantung dengan memanfaatkan system yang dapat dibuat untuk diagnosa awal pada gejala yang dialami. Yang pada penelitian ini akan menggunakan metode Modified K-Nearest Neighbor (MKNN) dalam mengklasifikasikan penyakit jantung berdasarkan kriteria atau gejala yang ada. Penelitian ini menggunakan 6 kriteria penyakit dan 3 kelas diagnosa penyakit jantung. Dengan melewati beberapa langkah pengerjaan yaitu menghitung jarak Euclidean, menghitung nilai validitas dan terakhir menghitung weight voting dengan mengandalkan nilai K yang telah ditentukan sejak awal perhitungan. Pada penelitian ini telah ditentukan nilai K=5 dan didapat hasil pengujian akurasi sebesar 85%, dengan recall 90% dan precision 85%.
MINI-MULTILATERALISM IN NORTHEAST ASIA: IMPLICATIONS FROM EUROPE AND ITS ROLE IN RESOLVING KOREAN PENINSULA ISSUES
Authors: Stan Laura Florina , Chen Xiuli , He Yi , Chung Kyung-Young
Published: April 2024

Northeast Asian nations, including the critical historical fulcrum of the Korean Peninsula, must prioritize regional cooperation and trust-building to achieve their maximum regional and global potential. Through the study of four stages of regional growth, a roadmap towards integration that's contextualized within the unique socio-political dynamics of Northeast Asia is provided. Mini-multilateralism has historical relevance for the Korean Peninsula whose complexities and sensibilities arising from the peninsula's divided past underscore the need for a strategy that supports smaller, more focused multilateral engagements. These engagements could provide a platform for resolving ongoing tensions while fostering regional cooperation, ultimately contributing to the construction of a secure Northeast Asia. The examination of historical incidents, particularly those related to the Korean Peninsula, shows the immense potential of mini-multilateralism as a strategy for advancing regional stability, building trust, and promoting cooperation. As such, the implications drawn from European experiences serve as lessons for Northeast Asia and particularly for resolving issues related to Korean history and its future.
Creating change through leadership development:
Authors: Ticoll Miriam , Iverson Sandy
Published: April 2024

In 2019, CHLA/ABSC launched the first Leadership Institute for health librarians in Canada. This article provides an overview of how the Leadership Institute (LI) was developed and delivered, the content and structure of the LI, lessons learned from evaluations of the program, and reflections of participants two years after the program was launched.
Political Activism and Other Predictors of Immigration-Status-Based Prejudice: Secondary Data Analysis of the World Values Survey
Authors: Ibrahim Bashirat Abiodun
Published: April 2024

Political activism is motivated by the desire for equity in the distribution of social values, raising curiosity about how activism plays out in matters of prejudicial sentiments. Therefore, this work was designed to examine the prediction of immigration-status-based prejudice by activism in a cross-national data context. The data used are secondary data from Wave 7 of the 2017-2021 World Values Survey (N=76 897) and the 2017-2020 European Values Survey (N=58 103), which were conducted in 81 different countries. Binary logistic regression featuring the Adjusted Odds Ratio (AOR) and the 95% confidence interval (CI) were used to analyze data. Results show that 21.7% of respondents were prejudiced against immigrants while the mean±SD of political activism was 6.46±2.26 (min.=4, max.=12). Politically active respondents were significantly less likely to have prejudice against immigrants (AOR=0.861; 95% CI=0.855, 0.866; p
Causality Analysis between BIST-100, Investor Risk Appetite, Exchange Rate, Inflation and Interest Rate in Türkiye Economy
Authors: Sözen Çağlar , Şeyranlıoğlu Onur , İspiroğlu Ferhat
Published: April 2024

In this study, econometric methods are used to investigate the causality relationships between key macroeconomic and financial indicators in Türkiye. The research focuses on the Türkiye economy and financial markets for the period 2011-2019. Monthly data of Borsa Istanbul (BIST-100), Investor Risk Appetite Index (RISE), exchange rate, inflation and interest rate are analyzed by using the Toda-Yamamoto causality test. Our findings show that there is one-way causality from BIST-100 index to inflation, exchange rate to inflation, investor risk appetite index to interest rate and BIST 100 index to investor risk appetite index. These results provide an understanding of the dynamic relationships between these indicators and provide implications for the Türkiye economy.
Sağlık Harcamaları ve Toplam Faktör Verimliliği Arasındaki İlişki: Türkiye’de Düzey-2 Alt Bölgeleri İçin Bir Uygulama
Authors: Aydın Rahman , Çakmak Erol
Published: April 2024

Sağlık harcamalarının ekonomik büyüme üzerine etkisini inceleyen ilk çalışma Mushkin (1962) tarafından ele alınmıştır. Bu çalışmada sağlık harcamalarının ekonomik büyümeyi olumlu etkilediği belirtilmiştir. Devam eden dönemlerde sağlık ve ekonomik büyüme ilişkisi, sağlığa dayalı büyüme hipotezi olarak literatürde yer almıştır. Bu hipotez özellikle yeni sağlık politikası uygulamalarına geçildiği 80’li yıllardan sonra birçok gelişmekte olan ülkelerde test edilmiştir. Bu çalışmada, Türkiye’de 2003-2019 yılları arasında Düzey 2 kapsamında yer alan 26 alt bölgede kamu sağlık harcamalarının ekonomik büyüme ve toplam faktör verimliliği üzerine etkisi araştırılmaktadır. Çalışmada ekonomik büyüme, kamu sağlık harcamaları ve kamu eğitim harcamaları verilerinin yanı sıra kontrol değişken olması amacı ile sabit sermaye yatırımları, ihracat, işgücü stoku ve ortalama yıllık hava sıcaklığı verileri de kullanılmıştır. Verilerin zaman boyutunun kısa olması nedeniyle Panel EKK yöntemi ve bu yöntemden türetilen en uygun tahminciler ile sağlığa dayalı büyüme hipotezinin geçerliliği araştırılmıştır. Elde edilen bulgulara göre sağlığa dayalı büyüme hipotezinin Düzey 2 kapsamındaki TR32, TR41 ve TR83 bölgelerinde kabul edildiği belirlenmiştir.
Perfil de la empresa basada en datos
Authors: Gallardo Sara
Published: April 2024

Convencido de que el trabajo duro es necesario para utilizar los dones y las oportunidades, Luis Bernardo Chicaíza señala ese camino para gozar las cosas que más disfruta.
Karakteristik Daerah Aliran Sungai Klawoguk Di Kota Sorong, Papua Barat Daya
Authors: Mahmud  , Wijaya Danang Jatmika Wahyu , Wahyudi  , Nugroho Bambang , Dwiranti Febriza , Mutakim
Published: April 2024

Banjir telah menjadi musibah terbesar dalam dasawarsa terakhir.  Penelitian ini bertujuan untuk mengkaji karakteristik DAS (Daerah  Aliran Sungai)  Klawoguk yang diharapkan dapat berkonstribusi dalam perencanaan, pengelolaan dan mitigasi banjir di Kota Sorong.    Penelitian ini menggunakan metode survey, analisis spasial dan pengamatan lapang.  Hasil penelitian menunjukkan bahwa DAS Klawoguk memiliki tipe iklim tropik sangat basah dengan curah hujan sepanjang tahun tanpa dikenali musim kemarau.   DAS berbentuk lonjong berdampak air semakin lama untuk mencapai titik akir air.  Topografi datar seluas 2.599,30 ha telah menjadi wilayah perkotaan Provinsi Papua Barat Daya meliputi kelurahan Sawagumu, Malaingkedi, Klasabi, Kalwalu dan Klamana yang menjadi langganan banjir.  Dalam tujuh bulan terakhir koefisien regim aliran (KRA) berubah – ubah didominasi sangat rendah yang berarti aliran air pada sungai Klawoguk lebih stabil.  Sedimen didominasi sangat tinggi dan adanya degredasi hutan lindung oleh pengambilan tanah dan galian C yang menyebabkan peningkatan hasil sedimen pada sungai.
Conservation of Endemic Birds Through the Willingness to Pay Tourists in the Manusela National Park Eco-Tourism Area
Authors: Latupapua Yosevita Th. , Soselisa Fanny
Published: April 2024

Ecotourism management requires a lot of funds, so through ecotourism activities visitors can get involved in supporting the conservation of the area through willingness to pay (WTP). The purpose of this study was to determine the perceptions and preferences of tourists and the willingness to pay visitors (WTP) in supporting the conservation of typical bird species in MNP. Determination of the sample using accidental sampling technique. The number of samples used was 38 tourists. The characteristics and perceptions of visitors were analyzed using qualitative descriptive, while the willingness to pay of tourists used quantitative analysis. The results showed of the calculation WTP to support the conservation of endemic bird species through the management of birdwatching ecotourism attractions obtained a value of 2,000 000, -. This value indicates that the appropriate price for birdwatching ecotourism services in Masihulan Village for tourists is 2,000,000,-.