bluuebunny/crossref_metadata_2025 huggingface dataset:
Особенности оптического усиления в сильнолегированных Al-=SUB=-x-=/SUB=-Ga-=SUB=-1-x-=/SUB=-N:Si-структурах
Authors: Бохан П.А. , Журавлёв К.С. , Закревский Д.Э. , Малин Т.В. , Осинных И.В. , Фатеев Н.В.
Published: May 2021

Time-resolved luminescence and stimulated emission intensities has been experimentally investigated in heavily doped Al0.65Ga0.35N and Al0.74Ga0.26N structures under pulsed optical excitation. These results showed that the time decay of the luminescence and stimulated emission intensities for various wavelengths of the emitted spectrum and optical pumping intensities consisting of at least the fast and the slow components. Fast components with exponential time decay are responsible for the radiative recombination of nonequilibrium electrons on deep acceptors, while slow ones are responsible for the recombination of donor-acceptor pairs
Implementing Exercise in Standard Cancer Care (Bizi Orain Hybrid Exercise Program): Protocol for a Randomized Controlled Trial
Authors: Arietaleanizbeaskoa Maria Soledad , Gil Rey Erreka , Mendizabal Gallastegui Nere , García-Álvarez Arturo , De La Fuente Ibon , Domínguez-Martinez Silvia , Pablo Susana , Coca Aitor , Gutiérrez Santamaría Borja , Grandes Gonzalo
Published: May 2021

Background

Despite the established benefits of regular exercise for patients with cancer to counteract the deleterious effects of the disease itself and treatment-related adverse effects, most of them do not engage in sufficient levels of physical activity and there is a paucity of data on the integration of efficacious exercise programs that are accessible and generalizable to a large proportion of patients with cancer into routine cancer care.

Objective

We intend to examine the effects attributable to the implementation of a community-based exercise program on cardiorespiratory functional capacity and quality of life for patients with cancer.

Methods

This will be a hybrid study. In the first experimental phase, patients diagnosed with any type of cancer will be randomized into two parallel groups. One group immediately performs Bizi Orain, a 3-month supervised exercise program (3 times a week), in addition to behavioral counseling in a primary health care setting; the other is a reference group that starts the exercise program 3 months later (delayed treatment). In the second observational phase, the entire cohort of participants will be followed-up for 5 years. Any person diagnosed with cancer in the previous 2 years is eligible for the program. The program evaluation involves the uptake, safety, adherence, and effectiveness assessed after completion of the program and with follow-ups at 3, 6, 12, 24, 36, 48, and 60 months. The primary outcomes of the experimental study, to be compared between groups, are improved physical function and quality of life, whereas overall survival is the main objective of the prospective study. To analyze the association between changes in physical activity levels and overall survival, longitudinal mixed-effects models will be used for repeated follow-up measures.

Results

A total of 265 patients have been enrolled into the study since January 2019, with 42 patients from the hematology service and 223 from the oncology service.

Conclusions

Bizi Orain is the first population-based exercise program in Spain that will offer more insight into the implementation of feasible, generalizable, and sustainable supportive care services involving structured exercise to extend survival of patients with cancer, improve their physical function and quality of life, and reverse the adverse effects of their disease and related treatments, thereby reducing the clinical burden.

Trial Registration

ClinicalTrials.gov NCT03819595; http://clinicaltrials.gov/ct2/show/NCT03819595

International Registered Report Identifier (IRRID)

DERR1-10.2196/24835
Digital Solutions to Alleviate the Burden on Health Systems During a Public Health Care Crisis: COVID-19 as an Opportunity
Authors: Willems Sofie H , Rao Jyotsna , Bhambere Sailee , Patel Dipu , Biggins Yvonne , Guite Jessica W
Published: May 2021

The COVID-19 pandemic has generated unprecedented and sustained health management challenges worldwide. Health care systems continue to struggle to support the needs of the majority of infected individuals that are either asymptomatic or have mild symptoms. In addition, long-term effects in the form of long-lasting COVID-19 symptoms or widespread mental health issues aggravated by the pandemic pose a burden on health care systems worldwide. This viewpoint article considers aspects of digital health care solutions and how they can play an ongoing role in safely addressing gaps in the health care support available from initially and repeatedly overwhelmed providers and systems. Digital solutions can be readily designed to address this need and can be flexible enough to adapt to the evolving management requirements of various stakeholders to reduce COVID-19 infection rates, acute hospitalizations, and mortality. Multiplatform solutions provide a hybrid model of care, which can include mobile and online platforms accompanied by direct clinician input and feedback. Desirable components to be included are discussed, including symptom tracking, patient education, well-being support, and bidirectional communication between patients and clinicians. Customizable and scalable digital health platforms not only can be readily adapted to further meet the needs of employers and public health stakeholders during the ongoing pandemic, but also hold relevance for flexibly meeting broader care management needs into the future.
Developing a Risk Governance Framework on Radiological Emergency, Preparedness, and Response for Emergency Responders: Protocol for a Mixed Methods Study
Authors: Abd Rahman Anita , Abdul Manaf Rosliza , Lim Poh Ying , Suppiah Subapriya , Juni Muhammad Hanafiah
Published: May 2021

Background

Risk governance involves processes and mechanisms to understand how risk decisions are taken and executed. This concept has gained a reputation over time as being essential for emerging comprehensive management that defines the success of an organization. While guiding documents that explain the use of risk management related to nuclear safety and security are available worldwide, few locally conducted studies have explained risk governance practices in areas where hazard usage is known, such as in radiological emergencies.

Objective

This paper describes a protocol that was used to determine several factors that influence emergency responders’ perceptions toward radiological risk practices and visualize the risk radiological framework for emergency preparedness and response.

Methods

A mixed methods study with a convergent design was performed. A qualitative analysis was performed using a case study approach where 6 key informants were purposely sampled for in-depth interview, and a cross-sectional study involving a self-administered questionnaire was conducted among approximately 260 emergency respondents from national regulatory, research, and services organizations. NVivo (version 12, QSR International) was used to analyze the interview transcripts and emerging themes were identified through abductive coding. Simultaneously, multiple logistic regression analysis was used to determine significant predictors that form the equation model.

Results

The study is still underway. Qualitative findings were based on transcript-coding that informed the relevant thematic analysis, while statistical analyses including multiple logistic regression analysis measured the adjusted odds ratio of significant variables for the equation model. The study is expected to conclude in late 2021.

Conclusions

Important emerging themes and significant factors that are related to the emergency responders’ perceptions regarding radiological governance practices were determined through the convergent design. This potentially facilitated the development of a plausible radiological risk governance framework. Furthermore, our results will provide key insights that can be used in future studies.

International Registered Report Identifier (IRRID)

DERR1-10.2196/25877
Changes in Language Style and Topics in an Online Eating Disorder Community at the Beginning of the COVID-19 Pandemic: Observational Study
Authors: Feldhege Johannes , Moessner Markus , Wolf Markus , Bauer Stephanie
Published: May 2021

Background

COVID-19 has affected individuals with lived experience of eating disorders (EDs), with many reporting higher psychological distress, higher prevalence of ED symptoms, and compensatory behaviors. The COVID-19 pandemic and the health and safety measures taken to contain its spread also disrupted routines and reduced access to familiar coping mechanisms, social support networks, and health care services. Social media and the ED communities on social media platforms have been an important source of support for individuals with EDs in the past. So far, it is unknown how discussions in online ED communities changed as offline support networks were disrupted and people spent more time at home in the first months of the COVID-19 pandemic.

Objective

The aim of this study is to identify changes in language content and style in an online ED community during the initial onset of the COVID-19 pandemic.

Methods

We extracted posts and their comments from the ED community on the social media website Reddit and concatenated them to comment threads. To analyze these threads, we applied top-down and bottom-up language analysis methods based on topic modeling with latent Dirichlet allocation and 13 indicators from the Linguistic Inquiry and Word Count program, respectively. Threads were split into prepandemic (before March 11, 2020) and midpandemic (after March 11, 2020) groups. Standardized mean differences were calculated to estimate change between pre- and midpandemic threads.

Results

A total of 17,715 threads (n=8772, 49.5% prepandemic threads; n=8943, 50.5% midpandemic threads) were extracted from the ED community and analyzed. The final topic model contained 21 topics. CIs excluding zero were found for standardized mean differences of 15 topics and 9 Linguistic Inquiry and Word Count categories covering themes such as ED symptoms, mental health, treatment for EDs, cognitive processing, social life, and emotions.

Conclusions

Although we observed a reduction in discussions about ED symptoms, an increase in mental health and treatment-related topics was observed at the same time. This points to a change in the focus of the ED community from promoting potentially harmful weight loss methods to bringing attention to mental health and treatments for EDs. These results together with heightened cognitive processing, increased social references, and reduced inhibition of negative emotions detected in discussions indicate a shift in the ED community toward a pro-recovery orientation.
Association of Sleep Disturbances and Cognitive Decline among Cognitively Normal Elders Over Time (Preprint)
Authors: Guo Xiuhua , Nzoyoum Kuetche Mandela William , Zhang Meng , Liu Mengmeng , Liu Yue , Aklilu Deginet , Wang Wei , Wang Wei , Wang Xiaonan ,   Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Published: May 2021

BACKGROUND

While sleep disturbances (SD) has been shown to be associated with worse cognition, but the causal relationship between the two subjects to debate. Our objective was to investigate the longitudinal impact of SD on cognitive function.

OBJECTIVE

To determine the effect of self-reported clinical diagnosis of SD on longitudinal changes in brain amyloid-PET, CSF-biomarkers (Aβ42, T-tau and P-tau) and cognitive function in cognitively normal.

METHODS

A total of 463 cognitively normal elders (357 normal and 106 SD) were included. Alzheimer’s Disease Neuroimaging Initiative (ADNI) participants were collected from 2005 to 2020. The generalized linear mixed models adjusting variables which were selected by the Akaike Information Criterion (AIC) and the marginal effect estimation method was used to estimate the risk effect of SD. Cox proportional hazards regression models estimated the relative hazard of AD, among baseline SD patients.

RESULTS

The age range of participants was 73.60±5.71 years old, and the female proportion was 43.63%. In adjusted regression models, Participants with baseline SD had higher likelihood of developing worse cognition over subsequent follow-up, PACC (decrease 7.53 points [95%CI, 7.36-7.70]; P<0.001), MMSE (decrease 5.26 points [95%CI, 5.17-5.35]; P<0.001), and CDR–Sum of Boxes (increase 5.61 points [95%CI, 5.67-5.54]; P=0.001). Similarly, Cox regression analysis suggested that sleep disturbances is a risk factor of AD (HR=1.55, 95% CI=1.08 to 2.22).

CONCLUSIONS

SD probably is a warning sign of AD, because it is associated with greater likelihood of cognitive decline or dementia over time. Associations are likely multifactorial and could be explained by intervening variables in the path from SD to dementia, or by common risk factors for pathological processes in brain. These findings suggest need for more attentions of older adults with sleep compromise.
The Psychological Burden of Attention-Deficit/Hyperactivity Disorder Traits on Medical Workers Under the COVID-19 Outbreak: A Cross-Sectional Web-Based Questionnaire Survey (Preprint)
Authors: Matsui Kentaro , Yoshiike Takuya , Tsuru Ayumi , Otsuki Rei , Nagao Kentaro , Ayabe Naoko , Hazumi Megumi , Utsumi Tomohiro , Yamamoto Kentaro , Fukumizu Michio , Kuriyama Kenichi
Published: May 2021

BACKGROUND

There are numerous reports on the psychological burden of medical workers after the COVID-19 outbreak; however, no study has examined the influence of developmental characteristics on the mental health of medical workers.

OBJECTIVE

The objective of this study was to examine whether the developmental characteristics of medical workers are associated with anxiety and depression after the COVID-19 outbreak.

METHODS

An online questionnaire survey was conducted in October 2020. The questionnaire included items on sociodemographic data, changes in their life after the COVID-19 outbreak, and symptoms of depression, anxiety, attention deficit/hyperactivity disorder (ADHD) traits, and autism spectrum disorder traits. We performed hierarchical multiple regression analyses.

RESULTS

The data of 640 medical workers were analyzed. Increases in physical and psychological burden were observed in 49.1% and 78.3% of the subjects, respectively. The results of a multiple regression analysis showed that ADHD traits were significantly associated with both depression (β=0.390, P<.001) and anxiety (β=0.426, P<.001). Autistic traits were significantly associated with depression (β=0.069, P<.05) but not anxiety. Increased physical and psychological burden, being female, medical workers other than physicians and nurses, fear of COVID-19, and experience of discrimination were also significantly associated with both depression and anxiety.

CONCLUSIONS

Globally, the burden on medical workers increased. This study suggested that medical workers with higher ADHD traits may need special attention during the COVID-19 pandemic.
Vaccine-induced mutation in SARS-CoV-2, a matter of concern? (Preprint)
Authors: E M Annesh , Varghese Pulikkottil Raphael , Vasudevan Damodaran M , Kumar Anoop , Kuttichira Praveenlal
Published: May 2021

UNSTRUCTURED

The emergence of new lineages of corona virus over the different continents has illustrated a significant public health concern. These new strains have a higher rate of transmissibility and have become dominant within a short period of time. The virus strains were also witnessed with an extensive range of mutations in the spike (S) protein, particularly in the receptor-binding domain (RBD) and amino-terminal domain (NTD). The studies concerning the genomic epidemiology of the COVID-19 virus have assisted the scientific community to unveil the evolutionary aspect of viruses and track the transmission dynamics over the world. At present all the mutations are vaccine sensitive, but vaccine-resistant variety may emerge at any time. It is very important that we should close the door quickly, although, strategic problems are there. Mutations are more possible in partially vaccinated areas rather than fully vaccinated areas. The present policy of vaccinating on an age structure leaves many non-vaccinated in the same home. In a population with very few vaccinated people there are viruses in many hosts and the chances of mutation is high. If the population is fully vaccinated, the virus is eradicated from that community and hence mutation chances are less. This locality specific fast and total vaccination will curtail the mutagenesity of the virus, lead to its eradication and to be preferred rather than vaccinating based on age structure.
APOPTOSIS INDUCING EFFECT OF SILVER NANOPARTICLES SYNTHESIZED USING MAGNOLIA CHAMPACA LEAF EXTRACT ON MCF-7 CELL LINE
Authors: ANTONY ANNA , SHRIVASTAV NEHA , DUBEY SIDDHARTH , ACHARYA ASHUTOSH
Published: May 2021

Objective: To synthesize silver nanoparticle (AgNP) using the ethanolic leaf extract of Magnolia champaca (MC-AgNP) and to evaluate its cytotoxicity and apoptotic activity in MCF-7 cell line, and to analyse active Caspase-3 expression in inducing apoptosis.

Methods: AgNP was green synthesized using ethanolic leaf extract of MC. Shape and size were analysed by SEM and particle size analyser. Cytotoxicity was tested to find IC50 value. Apoptosis was explored by mitochondrial membrane potential (ΔΨm) assay and active Caspase-3 expression study using flow cytometry.

Results: AgNP synthesized was observed to be in spherical shape through SEM micrograph with 164.6 nm in size. IC50 value of 15.90 µg/ml was obtained after 24 h of drug treatment. Changes in ΔΨm and positive active Caspase-3 protein expression were observed.

Conclusion: The present results suggest that MC-AgNP has potential anticancer property and also induced cell death via apoptosis through caspase dependent pathway in MCF-7 cells.
FORMULATION AND EVALUATION OF ATORVASTATIN CALCIUM NANOCRYSTALS CONTAINING P-GLYCOPROTEIN INHIBITORS FOR ENHANCING ORAL DELIVERY
Authors: LABIB SARAH , NASR MOHAMED , NASR MOHAMED
Published: May 2021

Objective: The main objective of this study was to develop atorvastatin calcium (ATR) as an oral drug delivery system for a P-glycoprotein (P-gp) substrate drug using different pharmaceutical excipients that inhibit P-glycoprotein and evaluate the influence of nanocrystals on the dissolution characteristics and bioavailability compared to the plain drug.

Methods: A nanosuspension was prepared by Solvent-antisolvent precipitation method using a solvent containing stabilizer that act as a p-gp inhibitor dissolved in distilled water as polyethylene glycol 300, polyethylene glycol 400 (PEG 300, PEG 400), tween 20 and tween 80 while the solvent selected for atorvastatin calcium was methanol. The concentrations were as follows: PEG 300 and 400 = 0.25% w/v, tween 20 and 80 = 0.75% v/v. Nanocrystals were extracted from the suspension and characterized.

Results: Particle size of the drug was 1307±127.79 nm while the formulas prepared ranged from 223±17.67 to 887±58.12 nm. Pure ATR had a saturated solubility of 0.059±0.005 mg/ml and the prepared nanocrystals ranged from 0.32±0.021 to 0.88±0.019 mg/ml. The Percentage of drug released of plain atorvastatin calcium reached 41.49% while the formula ranged from 44.32 to 61.5%. Both XRD and SEM discussed the degree of crystallinity as follows: F1<F2<F4<F3<ATR.

Conclusion: 0.3% of PEG 300 and PEG 400 were not enough to formulate proper nanocrystals while 0.75% tween 20 and tween 80 achieved acceptable formulas. F4 which is prepared with tween 80 exhibited the highest enhancement in saturated solubility, dissolution rate and subsequently expected to have improved oral bioavailability.
Improving the Usability of Organizational Data Systems
Authors: Hou Chung-Yi , Mayernik Matthew S.
Published: May 2021

For research data repositories, web interfaces are usually the primary, if not the only, method that data users have to interact with repository systems. Data users often search, discover, understand, access, and sometimes use data directly through repository web interfaces. Given that sub-par user interfaces can reduce the ability of users to locate, obtain, and use data, it is important to consider how repositoriesâ€™ web interfaces can be evaluated and improved in order to ensure useful and successful user interactions. This paper discusses how usability assessment techniques are being applied to improve the functioning of data repository interfaces at the National Center for Atmospheric Research (NCAR). At NCAR, a new suite of data system tools is being developed and collectively called the NCAR Digital Asset Services Hub (DASH). Usability evaluation techniques have been used throughout the NCAR DASH design and implementation cycles in order to ensure that the systems work well together for the intended user base. By applying user study, paper prototype, competitive analysis, journey mapping, and heuristic evaluation, the NCAR DASH Search and Repository experiences provide examples for how data systems can benefit from usability principles and techniques. Integrating usability principles and techniques into repository system design and implementation workflows helps to optimize the systemsâ€™ overall user experience.
Ostrowski and Simpson type inequalities for multiplicative integrals
Authors: Ali Muhammad Aamir , Budak Hüseyin , Sarikaya Mehmet Zeki , Zhang Zhiyue
Published: May 2021

In this paper, we firstly obtain two identities for multiplicative differentiable functions. Then by using these identities, we establish Ostrowski and Simpson type inequalities for multiplicative integrals. At the end we give detail applications of our main results
On generalized ∗-reverse derivable maps
Authors: Sandhu Gurninder S. , Ferreira Bruno L. M. , Kumar Deepak
Published: May 2021

Let R be a ring with involution containing a nontrivial symmetric idempotent element e and δ: R → R be a generalized ∗-reverse derivable map. In this paper, our aim is to show that under some suitable restrictions imposed on R every generalized ∗-reverse derivable map of R is additive.
Baja graduación en posgrados: aplicabilidad y validez de los conceptos y categorías de Pierre Bourdieu para el análisis e interpretación de una carrera de Maestría
Authors: Godoy Ortiz Aníbal , Damián Ferro Mariano
Published: May 2021

La baja graduación en carreras de posgrado es un fenómeno complejo y multicausado. Una de las formas en que se manifiesta es el síndrome “Todo Menos la Tesis” (tmt), referido a la fuerte tendencia a la realización de estudios de posgrado (maestría y doctorado) el cursado y aprobación de todos los cursos y/o seminarios, a excepción de la tesis final y su defensa pública. El problema de la graduación en las carreras de posgrado que requieren para su aprobación la elaboración de una tesis es reconocido por su carácter universal. Sin embargo, su magnitud es mayor en América Latina que en los países desarrollados. En este artículo indagamos posibles aplicaciones de la teoría sociológica de los campos de Bourdieu, la cual ha sido poco utilizada en investigaciones sobre el tema. Nuestro objetivo es explorar el potencial de una serie de conceptos cruciales de Bourdieu como marco teórico adecuado para la comprensión e investigación sobre el síndrome de tmt. Este trabajo, a su vez, es producto de una fase preliminar de una propuesta de intervención, para la mejora de la tasa y tiempos de graduación de una carrera de Maestría, en un ámbito castrense, en Argentina.
Viaje a la semilla de la “portugalidad” moderna: de Viagens na minha terra, de Almeida Garrett, a los primeros pasos del turismo cultural en Portugal
Authors: Gómez Vázquez José Luis
Published: May 2021

Este artículo esboza una lectura de Viagens na minha terra, del escritor portugués Almeida Garrett, centrada en la necesidad de una mirada crítica respecto a la situación portuguesa a mediados del siglo xix, en un contexto europeo de gran agitación política y desarrollo industrial. Esta lectura resalta la peculiaridad del viaje que da origen a la obra —es decir, un viaje al interior del territorio portugués que se presenta como una inversión de las narrativas nacionales tradicionales de viaje relacionadas con los descubrimientos y las expediciones ultramarinas—. Por otra parte, esta lectura atiende el valor simbólico de la ciudad visitada por el autor, Santarém, donde tiene lugar una visión del devenir nacional. A partir de esta visión, el autor señala un rumbo para el desarrollo del país y de sus autorrepresentaciones, entre las cuales se atraviesa el reconocimiento de que Portugal ha dejado de ocupar un lugar central en las dinámicas del mundo moderno y ha pasado a ocupar un lugar en la periferia, desde la cual habrá de esforzarse por construir una imagen de sí mismo, además de debatirse entre las representaciones tradicionales y una imagen de modernidad que será proyectada a la exterioridad, principalmente a través de la valoración de su patrimonio histórico y su sucesiva incorporación a una industria turística, aún en ciernes.
Examining personification in songs as one of the English teaching materials
Authors: Fata Ika Apriani , Aprilya Annisa
Published: May 2021

This research aims to figure out the types of personification used in one of the famous albums namely Michael Jackson's Thriller and Invincible. The sources of data were 19 songs taken from Thriller and Invincible albums by Michael Jackson and the lyrics of the songs. The research design used was descriptive qualitative research with documentation analysis as the technique of data collection. The result showed that there were 65 personification expressions found in the albums. Those 65 personifications were categorized into four types of personification as proposed by Dorst et al. (2011) namely: conventionalized personification (33 expressions), novel personification (20 expressions), default personification (12 expressions), and personification-with-metonymy (0 expressions). The idea of conventionalized personification presents in the lyrics is to dig out the beauty and tranquility of nature to life. It also might address giving an object or animal-human characteristics to create interesting imagery to the ELT Students. Also, these songs are assumed as one of the various English materials in language teaching in the future since it has no sarcasm and motivating contexts throughout the lyrics themselves.
Creative techniques for online learning assessment
Authors: Rambe Sokhira LindaVinde
Published: May 2021

Online learning has been becoming a solution for schools, institutions, and universities that cannot run face-to-face learning. During the online learning process, there are challenges that stakeholders including teachers and lecturers often face. One of the challenges is in choosing assessment techniques which in this case is related to English learning assessment. Thus, the objective of this study is to elaborate some effective techniques for English learning assessment. Qualitative research was applied as a research design conducted at the English Education Department of the Institute for Islamic Studies of Padangsidimpuan. Ten lecturers of the English Department were chosen purposively as respondents and interview was used as a data collection technique. Then, data were analyzed through qualitative data analysis in which the data were described and elaborated in detailed ways. The findings revealed that there were many techniques that could be applied in English assessment methods. Among the methods are online tests using Google form application, discussion, and problem-solving, writing essays and summary, online presentation, multimedia presentation, mini-research, voice thread, storytelling, recording performance, online interview, and making content on social media. The study also unveiled that lecturers’ creativity is needed to create an objective and effective assessment for online learning.
English Medium Instruction (EMI) practice: Higher education internationalization in Indonesia
Authors: Simbolon Nurmala Elmin
Published: May 2021

Indonesian universities are striving to obtain international recognition in this global competition of higher education. In doing so, many offer English Medium Instruction (EMI) courses. However, there is no documentation of the arrangement of EMI practice in Indonesian universities. This article presents a picture of the current implementation of EMI in some universities as one strategy to obtain international recognition. Survey research is selected to gather some key issues surrounding the implementation of EMI. A questionnaire is administered to 30 universities, and half of them returned the responses. Data analysis uses a descriptive approach. Findings show that the main reason for EMI practice in most Indonesian universities is to address current competition among global universities. Higher education internationalization is indicated in using the English language in two main types of EMI classes: 'Bilingual Class' and 'International Class'. This study also highlights the limited understanding of EMI practice implications in Indonesian universities, especially regarding relevant support given to both EMI students and lecturers. Some key suggestions from the research include incorporating English for Specific Purposes (ESP) in EMI programs and the importance of stimulating collaboration between both content and English lecturers.
Efeitos do fitoterápico Phaseolus vulgaris L. sobre a saciedade durante o tratamento da obesidade.
Authors: Nunes Maria Clara Francisco , Ramos Marclênia Eduardo , Parreira Erika Cardoso Abud
Published: May 2021

A obesidade é um problema mundial de saúde e em consequência houve uma expansão de tratamentos para o mesmo, dentre os quais se destaca o controle da dieta, aliado ao uso de medicamentos fitoterápicos. Foi realizada revisão, em periódicos indexados sobre as propriedades da Phaseolus vulgaris L. (Feijão), objetivando avaliar a sua eficácia sobre a saciedade e consequente perda de peso em indivíduos obesos.  Para a composição do estudo, fora realizada consulta aos descritores nas línguas portuguesa, inglesa e espanhola, através da biblioteca virtual Descritores em Ciência da Saúde (DeCS) e buscas nas bases de dados PubMed, SciELO e LILACS. A literatura aponta um efeito positivo da substância ativa de Phaseolus vulgaris L. sobre a saciedade e perda de peso. Dessa forma, pode ser considerada um adjuvante ao tratamento da obesidade, porém são necessários novos estudos clínicos a fim de comprovar a sua eficácia.
Fatores associados à afiliação religiosa em adolescentes do ensino médio.
Authors: Almeida Claudio Bispo de , Veiga Luciene Dias Bispo , Barbosa Franck Nei Monteiro , Casotti Cezar Augusto
Published: May 2021

O presente estudo teve o objetivo de estimar a prevalência e fatores associados à afiliação religiosa em escolares do município de Jequié, Bahia, Brasil. Trata-se de estudo epidemiológico transversal, de base escolar, com amostra aleatória simples de adolescentes. Utilizou-se para obtenção dos dados um questionário, e para análise regressão logística. Participaram do estudo 840 adolescentes, e prevaleceram aqueles: do sexo feminino (60%); na faixa etária de 17 a 19 anos (51%); com consumo adequado de frituras (63,9%), frutas (73,3%) e verduras (66,2%), e consumo inadequado de doces (59%); inativos fisicamente (55,7%); e relataram possuir alguma afiliação religiosa (84,6%). Adolescentes de ambos os sexos, com maior faixa etária, e filhos de mães com melhor nível de escolaridade tiveram mais chances de possuir afiliação religiosa. Assim, conclui-se que o desfecho foi associado ao sexo e ao nível de escolaridade das mães. Sugere-se a realização de estudos que aprofundem as relações do desfecho com o estilo de vida nesta população.
Global uniqueness in an inverse problem for a class of damped stochastic plate equations
Authors: Zhao Qingmei , Yu Yongyi
Published: May 2021

This paper deals with the global uniqueness of an inverse problem for
the stochastic plate with structural damping. The key point is the
Carleman estimate for the fourth order stochastic plate operators dyt −
ρ∆ytdt + ∆2ydt. To this aim, a weighted point- wise identity for a
fourth order stochastic plate operator is established, via which we
obtained the desired Carleman estimate for the corresponding stochastic
plate equation with structural damping.
Aprendizaje autorregulado y gamificación en educación superior: propuesta de un modelo de análisis
Authors:   Universidad Rey Juan Carlos, García Magro Cristina , Martín Peña María Luz
Published: May 2021

El objetivo del presente trabajo es proponer un modelo conceptual que relacione la influencia de un contexto gamificado sobre los aspectos relacionados con la autorregulación en el aprendizaje. Si bien la literatura sobre el tópico aprendizaje autorregulado es extensa, el entorno ha sido poco explorado e inexistentes los trabajos que consideren la gamificación como herramienta eficaz para generar un contexto de enseñanza-aprendizaje favorable para estimular la autorregulación. La unión de las dos líneas de investigación estudiadas hasta el momento de forma aislada puede incentivar a la comunidad docente a orientar sus esfuerzos hacia el diseño de sistemas gamificados dentro del aula para instruir y fomentar la autorregulación. El modelo propuesto presenta las variables clave que considerar, con una justificación teórica sólida para las proposiciones planteadas.
Diseño y validación de un instrumento para valorar la convivencia escolar percibida por los estudiantes
Authors:   Universidad de Alcalá, Torrego Seijo Juan Carlos , García Sanz M.ª Paz , Hernández Prados M.ª Ángeles , Bueno Villaverde Ángeles
Published: May 2021

Un buen clima de convivencia en los centros educativos puede mejorar el bienestar, la autoestima, los resultados académicos del alumnado y prevenir conductas desadaptativas. Existen cuestionarios que evalúan la convivencia cuantificando los tipos de problemas, pero muy pocos instrumentos se centran en su gestión e implementación de programas. El objetivo de esta investigación es validar un cuestionario de evaluación de la gestión de la convivencia escolar desde la percepción del alumnado, centrado en el modelo integrado de la convivencia. Para ello, se ha realizado un muestreo aleatorio por conglomerados y estratificado en el que han participado 1169 estudiantes de 34 centros de 6.º de Primaria y Secundaria de la Comunidad Autónoma de Madrid. Tras la validación por juicio de expertos, se han empleado los programas SPSS v24 y AMOS para realizar el análisis factorial exploratorio y confirmatorio, respectivamente. Los resultados arrojan 4 factores, cuyos índices de fiabilidad oscilan entre .737 y .859 (Factor 1: marco protector de la convivencia; Factor 2: programa de alumnos/as mediadores; Factor 3: programa de alumnos/as ayudantes; Factor 4: procesos democráticos de elaboración de normas). Finalmente, se confirma el ajuste empírico al modelo integrado de mejora de la convivencia.
Implicaciones educativas y sociales del Aprendizaje-Servicio con métodos mixtos a través de un meta-análisis
Authors:   Universidad Complutense de Madrid, Bonastre Carolina , Camilli Celia , García-Gil Desirée , Cuervo Laura
Published: May 2021

El Aprendizaje-Servicio (ApS) se presenta como un modelo capaz de mejorar la calidad educativa, el rendimiento académico y las com- petencias cívicas y sociales de los estudiantes. Este estudio pretende, a través de un meta- análisis, sintetizar los resultados de investigación publicados hasta la fecha sobre ApS en artículos científicos que han empleado un enfoque mixto de investigación. Los resultados indican que el ApS parece producir mejoras importantes en los estudiantes, principalmente en la adquisición de conocimiento (d=1.07), con un tamaño del efecto igualmente gran- de en los escasos estudios con grupo control (d=0.89), aunque menor en la actitud hacia el servicio (d=0.45), no encontrándose efectos significativos cuando se comparan estas variables con variables dependientes, como duración del programa, género y tamaño de la muestra. Además, hay una gran heterogeneidad en los modos de evaluación y en los instrumentos de medida. La mayoría de los estudios tienen una calidad metodológica baja, a pesar de que la investigación sobre el tema se va incrementado notablemente. Se concluye que el ApS produce beneficios en los estudiantes que llevan a cabo el servicio, pero para poder apreciar la casuística de los resultados, los diseños de in- vestigación tendrían todavía cierta capacidad de mejora. Se sugiere elaborar protocolos de investigación homogéneos y se aconseja que el ApS con metodología mixta se extienda a las diferentes disciplinas, entre ellas las artísticas, y a todos los niveles educativos.
Apuntes para una historia de la Clarificación de valores: origen, desarrollo, declive y reflexiones
Authors:   Universidad de Navarra, Dabdoub Juan P.
Published: May 2021

La educación en valores morales es un ámbito que ha generado polémica en los siglos XX y XXI, especialmente por un rechazo social hacia el posible adoctrinamiento de los estudiantes. La metodología de Clarificación de valores de Louis Raths fue una de las propuestas más representativas que intentaron plantear una educación moral libre de adoctrinamiento. Sin profundizar en argumentos filosóficos que ya han sido tratados en numerosas publicaciones, el artículo estudia la historia de este planteamiento, para aprender de los esfuerzos, retos, victorias y fracasos de aquellos que nos han antecedido en la tarea de educar ciudadanos con convicciones morales. El artículo comienza exponiendo los puntos principales del pensamiento del psicólogo Carl Rogers que más influyeron en el origen de esta metodología. Después, se introduce el contexto social en el que surge el programa de la Clarificación de valores, una descripción detallada de sus notas esenciales, la buena acogida que recibió y, por último, las críticas y evaluaciones que condujeron a su vertiginoso declive. A modo de conclusión, se presentan tres breves reflexiones sobre la educación moral que, aunque no son novedosas, se ven reforzadas por el estudio realizado en este artículo.
The Influence of Transformations in the Modern Labour Market on Foreign Language Courses at Universities
Authors:   Lomonosov Moscow State University, Vorontsova Marina , Klyukina Evgeniya ,   Lomonosov Moscow State University
Published: May 2021

The topicality of the study is determined by the discord between the foreign language teaching standards in Russian universities and undergraduate and graduate students’ requirements oriented towards the modern labour market. Having obtained a specialty, university graduates may work in different fields or change their job profile altogether; the borders of professions and professional standards are undergoing changes as well. The aim of the study is to show the necessity to transform foreign language teaching standards at the university level in accordance with the recent and ongoing changes in the job market. The hypothesis of the study is that foreign language teaching standards in Russia should integrate communicative competence, critical and creative thinking, and learning to learn as necessary components. It is suggested that students of non-philological specialties should be taught two or three foreign languages instead of only advancing their command of English. The hypothesis was confirmed by the polls conducted among undergraduate and graduate students of the College of Asian and African Studies (CAAS, Lomonosov MSU), over 2019-2020. The study resulted in developing a new standard of teaching foreign languages at the CAAS, which includes teaching two European languages alongside an oriental/African one, and creating a new structure of the English language course oriented towards developing soft skills rather than a purely linguistic component. Thus, the study seeks to substantiate the need for the new standard by the requirements of the modern job market and graduates’ demands. Creating the new standard targeting soft skills development and teaching two European languages is a practical result of this work.
The Roman domination number of some special classes of graphs - convex polytopes
Authors: Kartelj Aleksandar , Grbic Milana , Matic Dragan , Filipovic Vladimir
Published: May 2021

In this paper we study the Roman domination number of some classes of planar
graphs - convex polytopes: An, Rn and Tn. We establish the exact values of
Roman domination number for: An, R3k, R3k+1, T8k, T8k+2, T8k+3, T8k+5 and
T8k+6. For R3k+2, T8k+1, T8k+4 and T8k-1 we propose new upper and lower
bounds, proving that the gap between the bounds is 1 for all cases except
for the case of T8k+4, where the gap is 2.
Influence of yeast extract enrichment on fermentative activity of Saccharomyces cerevisiae and technological properties of spelt bread
Authors: Vucurovic Vesna , Radovanovic Vesna , Filipovic Jelena , Filipovic Vladimir , Kosutic Milenko , Novkovic Nebojsa , Radojevic Vuk
Published: May 2021

Considerable interest in the consumption of bread from ancient spelt wheat with superior nutritional properties, easy digestibility and pleasant taste and aroma, has arisen recently. Yeast extract (YE) is nowadays frequently used as a natural flavor enhancer for improving organoleptic properties such as meaty, cheesy and savory attributes of different food products. YE is a natural product from the baker?s yeast industry with high nutritional richness containing amino acids, peptides, nucleotides, vitamins and minerals. In this work, the effect of YE, table salt and white sugar content on fermentative activity of yeast and technological properties of spelt bread was investigated by response surface methodology (RSM) aiming to define the optimal conditions for obtaining a new functional product. The addition of YE, salt and white sugar slightly decreased yeast fermentative activity, while CO2 retention in dough was found to depend more on its chemical composition. YE addition (up to 5%) was found to increase volume and decrease firmness of bread prepared from dough with sugar content up to 5%, while the opposite effect was established in bread with higher sugar content. Maximal bread elasticity was obtained for YE content of 1.57%, table salt content of 2.01% and sugar content of 7.15%.
Metformin Affects Gut Microbiome Composition and Function and Circulating Short-Chain Fatty Acids: A Randomized Trial
Authors: Mueller Noel T. , Differding Moira K. , Zhang Mingyu , Maruthur Nisa M. , Juraschek Stephen P. , Miller Edgar R. , Appel Lawrence J. , Yeh Hsin-Chieh
Published: May 2021

OBJECTIVE

To determine the longer-term effects of metformin treatment and behavioral weight loss on gut microbiota and short-chain fatty acids (SCFAs).

RESEARCH DESIGN AND METHODS

We conducted a 3-parallel-arm, randomized trial. We enrolled overweight/obese adults who had been treated for solid tumors but had no ongoing cancer treatment and randomized them (n = 121) to either 1) metformin (up to 2,000 mg), 2) coach-directed behavioral weight loss, or 3) self-directed care (control) for 12 months. We collected stool and serum at baseline (n = 114), 6 months (n = 109), and 12 months (n = 105). From stool, we extracted microbial DNA and conducted amplicon and metagenomic sequencing. We measured SCFAs and other biochemical parameters from fasting serum.

RESULTS

Of the 121 participants, 79% were female and 46% were Black, and the mean age was 60 years. Only metformin treatment significantly altered microbiota composition. Compared with control, metformin treatment increased amplicon sequence variants for Escherichia (confirmed as Escherichia coli by metagenomic sequencing) and Ruminococcus torques and decreased Intestinibacter bartlettii at both 6 and 12 months and decreased the genus Roseburia, including R. faecis and R. intestinalis, at 12 months. Effects were similar in comparison of the metformin group with the behavioral weight loss group. Metformin versus control also increased butyrate, acetate, and valerate at 6 months (but not at 12 months). Behavioral weight loss versus control did not significantly alter microbiota composition but did increase acetate at 6 months (but not at 12 months). Increases in acetate were associated with decreases in fasting insulin. Additional whole-genome metagenomic sequencing of a subset of the metformin group showed that metformin altered 62 metagenomic functional pathways, including an acetate-producing pathway and three pathways in glucose metabolism.

CONCLUSIONS

Metformin, but not behavioral weight loss, impacted gut microbiota composition at 6 months and 12 months. Both metformin and behavioral weight loss altered circulating SCFAs at 6 months, including increasing acetate, which correlated with lower fasting insulin. Future research is needed to elucidate whether the gut microboime mediates or modifies metformin’s health effects.
Pancreatic Pseudoislets: An Organoid Archetype for Metabolism Research
Authors: Friedlander Mollie S.H. , Nguyen Vy M. , Kim Seung K. , Bevacqua Romina J.
Published: May 2021

Pancreatic islets are vital endocrine regulators of
systemic metabolism, and recent investigations have increasingly focused on
understanding human islet biology. Studies of isolated human islets have
advanced understanding of the development, function, and regulation of cells
comprising islets, especially pancreatic α-
and β-cells. However, the multicellularity of
the intact islet has stymied specific experimental approaches—particularly in genetics
and cell signaling interrogation. This barrier has been circumvented by the
observation that islet cells can survive dispersion and reaggregate to form
‘pseudoislets’, organoids that retain crucial physiological functions,
including regulated insulin and glucagon secretion. Recently, exciting advances
in the use of pseudoislets for genetics, genomics, islet cell transplantation,
and studies of intra-islet signaling and islet cell interactions have been
reported by investigators worldwide. Here we review molecular and cellular
mechanisms thought to promote islet cell reaggregation, summarize methods that
optimize pseudoislet development, and detail recent insights about human islet
biology from genetic and transplantation-based pseudoislet experiments. Owing
to robust, international programs for procuring primary human pancreata,
pseudoislets should serve as both a durable paradigm for primary organoid
studies and as an engine of discovery for islet biology, diabetes, and
metabolism research.
The value of emptiness: MUJI’s strategies
Authors: Petitimbert Jean-Paul
Published: May 2021

Setting the scene1. Advertising emptiness2. Designing emptiness3. Going further : ethics and æsthetics4. Ways of doing — ways of beingConclusion
Contamination sensible et responsabilité par temps de pandémie
Authors: Ben Msila Anouar
Published: May 2021

PlanPréliminaires1. Contexte global : d’un imprévu l’autre2. Retour en force du réel3. De la contamination infectueuse à la contamination sensible4. Visage masqué : de la responsabilité pour autrui à la responsabilité d’autruiPour finir
ENSINO REMOTO: PERCEPÇÕES DE PROFESSORES QUE ENSINAM MATEMÁTICA
Authors: Macêdo de Moraes Eriene , Lima da Costa Walber Christiano , Araújo Passos Vânia Maria de
Published: May 2021

Durante grande parte do ano de 2020, o mundo enfrentou uma pandemia (Covid-19) que potencializou incertezas vivenciadas nesse período. Este artigo tem por intento promover reflexões sobre o ensino da matemática no cenário remoto através da formação continuada desenvolvida através do aplicativo Google Meet com professores que ministraram aulas de matemática para os anos finais do Ensino Fundamental nos municípios de Luís Eduardo Magalhães-BA e Palmas-TO. O público da referida formação compõe o quadro de participantes numa pesquisa de mestrado cujo tema é formação continuada no espaço escolar: práticas criativas e a interinstitucionalidade. A metodologia utilizada foi a pesquisa participante, com abordagem qualitativa com caráter descritivo, direcionada pelos instrumentos: relatos dos professores e observação in loco. Os dados produzidos foram analisados mediante pesquisa bibliográfica. As considerações revelam reflexões acerca das dificuldades e possibilidades no ensino remoto, além de balizar a relevância da formação continuada.