bluuebunny/crossref_metadata_2025 huggingface dataset:
Therapeutic methods for lipomyelomeningocele: literature review
Authors: Lougon Isabela Turino , Oliveira Taciana Maria Rolim Sampaio , Francisco Yan Ribeiro
Published: December 2021

Introduction: Lipomyelomeningocele is a congenital malformation in which the neural plate lies outside the spinal canal. Patients younger than 6 months of age are neurologically asymptomatic. However, if not diagnosed, the disease evolves with deterioration of bowel and bladder functions and, later, with motor deficits (paralysis) and loss of sensation. Accordingly, a literature review was developed about the therapeutic methods that enable a better quality of life and prevent or control disease progression. Objectives: This literature review aims to elucidate leading updates in the literature regarding the therapy for lipomyelomeningocele, a rare form of spinal dysraphism. Methods: Searches were performed in the LILACS e PubMed database and in the health descriptors (DeCs/MeSH), to establish the descriptors. Of the 6,292 articles found, 20 were selected, since only they presented relevant information about this topic. Results: From reading the articles, it was concluded that surgery is the recommended treatment for cases of lipomyelomeningocele. The main goal of surgery is to prevent future damage or further neurological deterioration and also to preserve or improve current neurological function. The widespread use of advanced prenatal ultrasonography can show neural development and suggest congenital malformations and progressive neurological deterioration. Conclusions: Although surgery is the best treatment, it may also be accompanied by outcomes such as meningitis, CSF leakage, neurological deterioration as a result of tethered cord or secondary to nerve injury, and incomplete healing or wound breakdown. Prenatal ultrasound is necessary to identify the malformation and support early diagnosis of lipomyelomeningocele and may open doors for future care and treatment.
Transcranial Direct Current Stimulation in the Management of Chronic Low Back Pain: A Systematic Review
Authors: Gioia Carolina Gabriela Divino Soares , Lellis Caio de Almeida , Borges Caio Reis , Puton Camila , Oliveira Giovanna Garcia de , Silva Ledismar José da
Published: December 2021

Introduction: Chronic Low Back Pain is a condition associated with changes in different brain regions, related to pain, posture and emotions. Objectives: Review the current literature about the efficiency and safety of Transcranial Direct Current Stimulation in the management of Chronic Low Back Pain. Design and setting: This is a systematic review of the literature conducted at the Pontifical Catholic University of Goiás. Methods: A systematic review of literature was conducted in the PubMed, BVS and Lilacs databases, with the following research strategy: “(Transcranial Direct Current Stimulation or TDCS) and (Low Back Pain)”. Randomized studies, clinical trials and case reports published in the last 10 years were selected. Results: A clinical trial showed that TDCS of the primary motor cortex (M1) for 20 minutes improved posture, balance and pain intensity of patients with CLBP. Also, a randomized clinical trial concluded that this technique, at 2-mA intensity, showed a significant reduction in CLBP. On the other hand, two randomized clinical trials showed that the results obtained did not support the application of the TDCS method for the treatment of CLBP, since the observed groups did not show considerable difference after stimulation. In addition, another double-blind controlled study also showed that TDCS over M1 did not influence the quality of patients’ CLBP. Conclusion: A conflict was noticed between the conclusions of the articles used to compose this review, that’s why more studies with scientific rigor are needed.
Cannabidiol and the Management of Pediatric Neurological Disorders: A Systematic Review
Authors: Lellis Caio de Almeida , Herbas Marco Alejandro Menacho , Cunha João Cesar Pereira da , Paniago Samyla Coutinho , Diniz Paulo Sérgio Machado
Published: December 2021

Introduction: Due to an increase in cases of neurological disorders refractory to conventional treatments in pediatrics patients, other therapies have been sought. Objectives: To analyze the safety and efficacy of CBD in the management of neurological disorders in children. Design and setting: A systematic review conducted at the Pontifical Catholic University of Goiás. Methods: This is a systematic review carried out in PubMed, Lilacs and MedLine databases, with the descriptors: “(Pediatric OR Neurology) AND (Cannabidiol OR Cannabis)”, being selected only the randomized studies, meta-analysis and clinical trials published in the last 10 years. Results: One randomized trial concluded that daily oral CBD solution reduced the frequency of seizures in pediatric patients with Lennox-Gastaut syndrome (LGS). In addition, another study concluded that CBD (20 mg/kg/day) is associated with up to a 50% decrease in seizures in children with SLG and Dravet syndrome. Furthermore, it was pointed out that the association of oral CBD (2 to 5 mg/kg/day) with antiepileptic drugs caused a mean reduction of 36.5% of severe seizures. Finally, CBD enriched with 0.25% THC reduced spasticity, dystonia and pain intensity in children with complex motor disorder. Conclusion: CBD was shown to be safe and effective as a treatment for refractory epilepsies and complex motor disorder in pediatric patients, with no serious side effects reported.
The incidence of stroke in pediatric patients in Brazil
Authors: Fonseca Rafaela Sandes , Lordêllo Louise Seixas , Azevêdo Beatriz Gusmão , Oliveira Lara Teixeira de , Sousa Giovanna Carvalho , Rios Ana Carolina Pachêco de Menezes , Loula Lanna Victória , Barreto Gustavo Bomfim , Lima Raissa Barreto , Vilas-Boas Gustavo Sampaio , Carvalho Thaís Machado Belitardo de , Oliveira Isadora Abreu , Souza Matheus Campos Ribeiro de
Published: December 2021

Background: Stroke is rare in pediatric patients, but it is of paramount importance due to its serious complications. The study of the incidence of strokes in these patients is important for us to be able to adequate public health policies. Objectives: To evaluate the incidence of strokes in pediatric patients in Brazil. Design and setting: Descriptive, retrospective study, carried out using data from the Hospital Information System (SIH/SUS), from 2011 to 2020. Methods: Variables: brain stroke not specific for the hemorrhagic or ischemic type, mortality, hospitalizations, sex, ethnicity and age group from 0 to 19 years of age. Results: During the period from 2011 from 2020, there were a total of 6912 cases of stroke in the age group from 0 to 19 years; the highest incidence in 2019 (10.59%) and the lowest incidence in 2020 (8.65%.) The age group from 15 to 19 accumulated the greatest number of cases (60.40%). The total mortality rate was 8.12% (561 cases). The highest mortality rate was observed between 15 and 19 years of age (62.03%), and the lowest between 5 and 9 years of age(4.63%). The incidence was slightly higher in males (50.41%). Conclusions: Similar annual stroke rates were identified during the analyzed period, demonstrating the need for interventional actions to reduce its incidence. The non-specification of the hemorrhagic or ischemic types is a limiting factor, since the prevention management is different in each case. There was a higher prevalence, as well as a higher mortality rate, from 15 to 19 years.
Alzheimer’s in Paraná-Brazil Incidence on Hospitalizations and Mortality Rate 2014-2019
Authors: Palangani Emanoelle Aparecida , Dall'Asta Jéssica Almeida , Rabelo Patricia Dias , Rodrigues Rebecca Caroline Sanches , Guerra Letícia Teixeira Pinheiro , Bublitz Sandro Artur Veit , Campos Jordana Luiza Ferreira de , Peraro Gustavo Bacelar
Published: December 2021

Introduction: Alzheimer’s disease, is an progressive neurodegenerative pathology. Is the most prevalent dementia condition in the world, which entails many expenditures for public health. Methods: The analysis if there was a reduction or increase in the number of hospitalizations and mortality, between the interval from 2014 to 2019, with the age groups from 59 years to more than 80 years. The database used to collect information was the DATASUS. Results: The number of interactions related to Alzheimer’s disease in Paraná, in the age group 50 and 59 years between the years 2014 (2) and 2019 (2), there was no change in the percentage of cases. The group 60 and 69 years 2014 (8) and 2019 (7), a reduction of 12.50% is found. The 70 and 79 years old, 2014 (16) to 2019 (13); reduction 18.75% of hospitalizations. The population 80 and over, 2014 (26) and 2019 (29) there is and increase of 11.54% of cases. Mortality rates, 50 and 59 years 2014, in which no mortality rate was obtained in 2019 (50), there was an increase of 50 units. 60 to 69 years from 2014 (12.5) to 2019 (14.29) there is an increase of 14.32%. 70 to 79 years old, 2014 (6.25) to 2019 (7.69) we have an increase of 23.04%. The age group of 80 years and more in 2014 (19.23) to 2019 (27.59) there was an increase of 43.47%. Conclusion: Thus, demonstrating the importance of medical and family care for the elderly, providing them with quality of life.
Small Group Discussion, an Effective Tool for Learning
Authors: Sarfraz Farrukh , Razaq Nadeem , Sarfraz Fahad , Saif Ullah Muhammad , Jawad Imran , Saeed Rizwan
Published: December 2021

Introduction: With the rapid change in teaching methodologies small group discussion gained a lot of popularity due to its wide impact from multiple dimensions on the learning of students. It is not only influences the learning of the students but also polished many skills not previously explored by the student such as communication skills, leadership qualities, ethics of group dynamics, respect of views of peers and so many. Objective: To expedite the views of Second year MBBS students at Azra Naheed Medical College about Small group discussion. Material and Methods Study design: Quantitative, cross sectional study. Settings: Azra Naheed Medical College, Lahore. Duration: Six months i.e. 1st January 2021 to 30th June 2021. Data Collection procedure: This study is conducted at Azra Naheed Medical College, Lahore, a total of 150 students divided into 10 groups each comprising of 15 students participated in the study. Students and the facilitators were briefed about the study; the topic assigned to each group ware told them a couple of days before the session. Pre validated questionnaire from the department of medical education was used and the collected data was analyzed by using SPSS version 23. Research question: What is the perception of Second year MBBS students at Azra Naheed College, Lahore about small group discussion an effective tool for learning? Results: Majority of the students were satisfied with the punctuality, constructive feedback, role of facilitator, improvement in the communication skills, interaction and positive feedback. Conclusion: It concludes students learned how to maintain a good balance of the session. Our study provided enough opportunities to the students to focus on the dynamics of learning in a modern way of self-respect, respect to the peers, improved self-confidence, and importance of positive and constructive feedback and in the end how to summarize and conclude a session. Key words: small group discussion, student centered learning, integrated learning, lecture
Effect of Metabolism of Carbohydrate in Mammalian Tissues and Tumors on The Level of Enzymes Involved in Direct Oxidative Pathway
Authors: Nizami Saleha Akram , Fatima Sabahat , Khalil Anas , Rana Gul-E- , Ain Noor-Ul- , Ahmed Shaheen Bashir
Published: December 2021

Introduction: Literature review has revealed that the distribution of the enzymes of 6-phospo-gluconate dehydrogenase activities of some acetone derived tissues in animal tissue have so far not been investigated systematically. This leaves a gap for further investigation to explore the subject matter deeply. Method: Barium salts of D-Glucose 6-phosphate (0 6-P), 6-phosphogluconate (6-PO) and D-ribose 5-phosphate (R 5-P) are available and were used in our study. (TNP) triphosphopyridine was prepared and analyzed; its composition was 75% TNP without (DNP) diphosphopyridine nucleotide. Ice-cold isotone KCL (0-15M-KCL with 8ml, 0-02M-KHCO3) was disintegrated in 09 parts. It is done in a potter glass homogenizer or in a Nelco homogenizer. This is followed by centrifuging and dialysis of the supernatants. Heparinized blood 10ml was used for erythrocyte hemolysis, which was diluted with 10ml of water. 01 part of haemolysate was treated with 9 parts of isotonic KCI. Spectroscope is used to determine the dehydrogenase activity of dialyzed tissue. The method followed was of Glock and McLean. Study Design: Quantitative, cross sectional study. Settings: Institute of Biochemistry, Gulab Devi Educational Complex, Lahore Duration: 01 Year i.e. 1st July 2020 to 30th June 2021. Results: Enzymes activities of 6-PG dehydrogenase and Gluco-6- phospo dehydrogenase mentioned in table 1&2 in normal mammalian tissue and mammary glands. The results obtained on the tumour cells are given in table 3. These Values are within the limits in normal tissues whereas it becomes on higher side in lymphomas and sarcomas. Conclusion: This study shows some limitation that the maximum enzymic activities are determined, whereas in the intact cell other regulatory factors probably limit or control the activity of this pathway. Keywords: Gluco-6- phospodehydrogenase, 6-PG dehydrogenase, oxidative pathway, Ribose 5-Pentose, mammalian tissue
Abnormal Liver Function Test and Statins
Authors: Khalil Anas , Ain Qurat Ul , Mughal Aamir Abbas , Marvi Sharonia , Iqbal Nasir , Sarfraz Farrukh
Published: December 2021

Introduction: Statins or 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors are one of the foremost commonly endorsed medications in cardiac patients. A bit like any other lesson of drugs, they have the potential to cause liver harm over time indeed with reasonable utilize. This drug induced liver harm (DILI) can be either coordinate (hepatocellular) or peculiar. As with multiple other hepatic pathologies, DILI may be asymptomatic or clinically quiet. Subsequently, it is judicious to carry out liver work tests (LFTs) from time to time. LFTs are an inexpensive, noninvasive, and fast first-line examination to monitor liver status. Be that as it may, the design of liver damage with statin utilize isn't particular and a relationship over time may not be clear. Objectives: To assess the derangements in Liver function test with regard to statin utilization and decide if there is any correlation exists. Method: Retrospective Observational study conducted in Punjab Institute of Cardiology, Lahore, from 31st July 2020 to 30 June 2021. Data Collection Procedure: This study is conducted at Punjab Institute of cardiology, Lahore, a total of 100 patients admitted from 1st July 2020 to 30 June 2021 with ischemic heart diseases were considered for inclusion as this was retrospective observational cohort study. The patients already taken statin were included in this study. LFTs were noted before the start of statin in their records then during the use of statin at 3rd and 6th month with great care. The collected data was analyzed by using SPSS version 23. Results: A total number of 100 patients were included in this study after inclusion exclusion criteria. The ratio male to female is 3:2.Patients using two types of statin i.e. Atorvastatin 20mg and Rosuvastatin 10mg were included. LFTs elevation was seen in the study. Conclusion: The use of statins clinically proved insignificant elevation of LFTs and hence it is safe to prescribe. Keywords: (HMG-CoA) reductase, Liver finction tests, Statin, LFTs
A Qualitative Exploratory Study to Elucidate The Impact of Integration on Pre-Clinical Disciplines Compared to Disciplines-Based Curriculum
Authors: Raza Zaidi Syed Hussain , Yasmeen Rahila , Ahmed Khan Rehan , Arooj Mahwish , Mukhtar Sara
Published: December 2021

Introduction: While most of the institution in our country follow the Flexnerian model of medical education, only a handful of medical colleges have embraced the integrated medical curriculum. Literature on impact of integration on the preclinical disciplines is sparse. This study aims to elucidate the impact of integration on the preclinical disciplines, their content, teaching, learning, and assessment. Methods: This qualitative exploratory study was conducted at the University College of Medicine and Dentistry from July to September 2020. Twenty-one semi-structured interviews were conducted with the faculty members from pre-clinical disciplines (Physiology, Anatomy, Biochemistry, Pharmacology, Pathology, Forensic Medicine & Community Medicine). The data was recorded, transcribed, coded and thematic analysis was done by using Atlas Ti version 7. Results: The thematic analysis of the transcripts resulted in twenty subthemes, from which five themes emerged. The study revealed that the faculty of preclinical disciplines perceived that departmental identity has been compromised since the switch to integrated medical curriculum. But, the relationships, both intradepartmental and interdepartmental of preclinical disciplines have improved significantly. Moreover, the number and depth of topics has also been affected. But the students learning approach was of major concern for the respondents. The student’s performance in the assessments was affected due to their learning approaches. Even though the number of assessments were deemed adequate, the depth of assessments had been negatively affected as a result of integrated assessments. Conclusion: Integrated curriculum has profound impact on pre-clinical disciplines. Any institution that wishes to introduce a modular integrated curriculum should take into account the findings reported in this study. Keywords: preclinical disciplines, organ system-based curriculum, impact of integration, faculty perspective, exploratory study
Efficacy of Itraconazole vs Itraconazole Plus Isotretinoin in Treatment of Chronic Tinea
Authors: Ullah Naseem , Rahim Khan Abdur , Aslam Kalsoom , Obaid Syed Muhammad
Published: December 2021

Background: About 20 to 25% of the global population is affected by the fungal skin infections. Different antifungal drugs used in traditional doses have developed widespread resistance, necessitating the development of an efficient antifungal treatment. Objective: To assess efficacy of itraconazole vs itraconazole plus isotretinoin in treatment of chronic tinea. Methodology: This was comparative study conducted at the Department of Dermatology Qazi Hussain Ahmad Complex Nowshera and alshifa clinic and skin aesthetic, Nowshera for duration of one year from November 2020 to November 2021. In both group A and B, 40 individuals were taken randomly. Treatment of group A patients was done with oral itraconazole and isotretinoin while patients of group B treatment was done with oral itraconazole alone. All patients were monitored for four weeks to assess their responsiveness to therapy and side effects. Results: Complete cure response was recorded in all the patients of group A, while in group B, complete cure response was recorded in 20 (50%) patients. A statistically significant treatment response was observed between both the groups (p<0.05). There were 22 (55%) individuals in group A and 7 (17.5%) patients in group B who had cheilitis and dryness of the lips as major adverse effects. Conclusion: Our study concludes that combination therapy with oral itraconazole and isotretinoin is efficient and safe for the treatment of chronic tinea. Our study recommends conducting study based on large sample size for better results.
Techno-economic Analysis of Rooftop Photovoltaic System (RPVS) using Thin-Frameless Solar Panels for Household Customers in Indonesia
Authors: Rudationo Carolus Boromeus , Novianto Bangun , Yandri Erkata , Susanto Herry , Setyobudi Roy Hendroko , Uyun Aep Saepul , Nur Syukri Muhammad , Wahono Satriyo Krido , Widodo Wahyu , Zekker Ivar , Lomi Abraham
Published: December 2021

The availability of thin-frameless solar panels on the market today makes the installation of rooftop Photovoltaic (RPVS) systems more attractive. The purpose of this research is to analyze financially the use of thinframeless solar panels for on-grid RPVS by household electricity customers in Indonesia. The investment cost, the maintenance costs, and the electricity cost savings were involved for the financial analysis, such as Internal Rate of Return (IRR), Net Present Value (NPV), and Pay Back Period (PBP). The calculation is carried out for ideal conditions, the direction of a non-ideal rooftop and the yearly increase of electricity prices is 15 %. The analysis results show that the minimum available rooftop area is still sufficient for the rooftop area needs for solar panel placement, the thin solar panels are safer than standard solar panels, and savings on electricity payments for the return on investment of the RPVS is to be attractive with the IRR > 12 %. The average investment cost of the non-ideal condition is 8 % higher than the ideal condition. This study provides an overview to the policymakers and developers in exploiting the potential of RPVS, especially in Indonesia. For future research directions, this study needs to analyze the technical and economic feasibility of using hybrid smart-grid technology with batteries.
Literácia em saúde: estudo com diabéticos de município do Nordeste
Authors: Sousa Milena Nunes Alves de , Januário Kalina Lígia Alves de Medeiros , Estrela Yoshyara da Costa Anacleto , De Souza Joelly Holanda , Barreto Tarciane Rosa de Vasconcelos Silva , Araújo Jorge Vitor Barreto , Nogueira Raquel Bezerra de Sá de Sousa , Bezerra André Luiz Dantas
Published: December 2021

Objetivou-se avaliar o nível de literácia em saúde (LS) de pacientes diabéticos atendidos na Estratégia de Saúde da Família, correlacionando com o perfil social, demográfico e clínico e o risco de complicações decorrentes do diabetes. Foi realizada pesquisa de campo, transversal-quantitativa, que teve como cenário de estudo duas Unidades Básicas de Saúde localizadas em São José do Bonfim, Paraíba. A amostra foi composta por 52 pacientes e para a coleta de dados foi utilizado a versão abreviada do TOFHLA. A maioria de diabéticos eram do sexo feminino, entre 50 e 65 anos, casadas(os), de cor parda e com baixa renda. Verificou-se que os pacientes com menor idade e com maior nível de escolaridade foram os que mais acertaram os questionamentos do instrumento. Além disso, a maior parte da amostra está no tercil “adequado” de LS. A avaliação do nível de LS dos indivíduos com doenças crônicas não-trsnsmissíveis pode contribuir para a compreensão das dificuldades existentes na comunicação entre o paciente e o profissional de saúde, facilitando na autogestão da doença.
Índice de sonolência diurna e correlação com a qualidade de vida: estudo com discentes de medicina e docentes médicos
Authors: Sousa Milena Nunes Alves de , De Lucena Marianny Macêdo , Estrela Yoshyara da Costa Anacleto , De Souza Joelly Holanda , Brito Élyta Palloma Rodrigues , De Lima Júnior Umberto Marinho , Nogueira Tiago Bezerra de Sá de Sousa , Lucena Paulo Antônio Farias
Published: December 2021

Objetivou-se avaliar o índice de sonolência diurna entre os estudantes de medicina e os docentes médicos correlacionando-o com sua qualidade de vida (QV). Foi conduzida pesquisa de campo, com caráter descritivo e abordagem quantitativa, junto a 200 alunos do curso de Medicina e 20 docentes médicos. Os dados foram obtidos a partir de dois questionários validados no Brasil: A Escala de Sonolência de Epworth (ESE) e o instrumento WHOQOL-BREF. Quanto à análise dos dados, além de estatística descritiva, utilizaram-se testes inferenciais de correlação de Pearson, Teste t de Studant e teste de qui-quadrado de Pearson. Constatou-se que 69,1% (152 participantes) da amostra apresentou sonolência diurna excessiva, houve um elevado índice indicado pela escala ESS-BR, cuja média foi de 11,48 pontos considerando os 2 grupos. Contudo, esse índice foi maior entre os estudantes de medicina do que entre os docentes médicos e afetou mais o sexo feminino. Os resultados obtidos alertam à realidade preocupante vivenciada pelos acadêmicos de medicina, e apontam a necessidade da adoção de medidas, além do PRO-CURAR, a fim de melhorar a QV desse grupo.
Sintomas depressivos entre sobreviventes de câncer: frequência e fatores de risco
Authors: Sousa Milena Nunes Alves de , Azevedo Felipe Mello Raposo , Figueiredo Ricardo Cavalcante Oliveira Patrício de , Silva Laysa Miranda Formiga da , Silva Matheus Santos , Leite Felipe Germano Monteiro , Dias Thuany Rodrigues , Suarez Larissa de Araújo Batista
Published: December 2021

Objetivou-se identificar a frequência e fatores de risco para sintomas depressivos entre sobreviventes de câncer. Foi realizada uma revisão integrativa, em que se utilizaram os Descritores em Ciências da Saúde associados: depressão e sobreviventes de câncer, em suas versões portuguesas e inglesas. A pesquisa ocorreu no portal da Biblioteca Virtual em Saúde e na U.S. National Library of Medicine. Pré-selecionaram-se 361 documentos e após aplicação dos critérios de elegibilidade, foram incluídos 11 estudos. Os estudos indicaram que a depressão é comum entre os indivíduos sobreviventes de câncer, mas que a frequência e a gravidade dos sintomas depressivos variam, conforme fatores de exposição. Entre os fatores de risco, os mais citados foram os sociais, econômicos, fatores de estilo de vida e os clínicos. Os achados alertam para a observância de fatores de risco entre indivíduos com neoplasias e, especialmente, entre os sobreviventes de câncer. Assim sendo, é fundamental adotar estratégicas preventivas e de promoção da saúde.
A importância da identificação do perfil epigenético de metiltransferases de proteínas para a detecção e prognóstico de Leucemias Linfóides Agudas
Authors: Amorim Murilo , Melo Célio Amoêdo de , Barrros Shirley Barata , Silveira Michele Amaral da
Published: December 2021

Objetivo: Investigar as repercussões biológicas dos efetores de metilação proteica como alternativa para a detecção e prognóstico das Leucemias Linfoides Agudas (LLA). Métodos: Trata-se de uma pesquisa bibliográfica, do tipo integrativa. Possui um desenho observacional, transversal e de vertente qualitativa, com o enfoque de abordar aspectos referentes à epigenética do câncer e o papel de metiltransferases como efetores de metilação proteica para a detecção e prognóstico das leucemias linfoides agudas. Resultados e Discussão: Obteve-se 8 pesquisas que atendiam os critérios pré-determinados para análise e apresentação do seu conteúdo. Foi atribuída a vertente de busca com base na proposta do tema, que teve como função delimitar as formas de apresentação dos estudos. Os estudos tratam da importância do desenvolvimento de moduladores epigenéticos envolvidos na etiologia da doença, bem como na diferenciação, classificação e prognóstico. Conclusão: O presente estudo pôde corroborar para uma compreensão geral acerca da etiologia da LLA, bem como, fornecer insights sobre a identificação de alvos terapêuticos para o prognóstico dessa doença.
Gizi Seimbang pada saat Puasa untuk Meningkatkan Imunitas di Masa Pandemi Covid-19 pada Ibu di Desa Tonasa Kabupaten Gowa
Authors: Amelia AP A.Rizki , Ahri Reza Aril
Published: December 2021

Fasting Ramadan as worship has many benefits for health, so that these two goals can be achieved, it is necessary to regulate diet specifically, especially regulating nutritional intake during iftar and sahur. During fasting the diet will change, because it is only allowed to eat in the morning before dawn and at night. The stomach is left empty for about 13 hours. Generally, the body takes 3-5 days to adapt to a new diet. From the nutritional aspect, fasting will at least reduce nutritional intake, especially energy by around 20-30 percent. This community service activity is carried out using an action study method where mothers in Tonasa Village will practice cooking food according to the nutritional needs needed according to age, then increase knowledge and understanding of balanced nutrition during fasting for PKK mothers in RW 01 In addition, we as a service team will provide tips so that families can continue to do activities without feeling weak. The education provided is about balanced nutrition when fasting through Pre and Post Tests. The implementation time of the service is carried out for 4 months. The expected result of this service is that it can increase the knowledge and skills of mothers regarding a balanced nutritional menu during fasting.
Penanggulangan Stunting Melalui Modal Sosial di Desa Besmarak Kecamatan Nekamese Kabupaten Kupang
Authors: N Nursalam , Neolaka Melkisedek N.B.C. , Djani William , Toda Hendrik
Published: December 2021

Stunting is one of the public problems that need attention and handling. The incidence of stunting if leftunchecked  can have  implications  for  the  quality  of human  resources,  namely in  addition  to  risking  physicalgrowth barriers and children's vulnerability to disease, it also causes cognitive development barriers that will affectchildren's intelligence and productivity levels in the future. The community service (PPM) which is carried out in theform of counseling in Besmarak village, Nekamese sub-district, Kupang regency is expected to provide knowledgeto  the  community  that  solving  the  stunting  problem  is  not  only through health and nutrition improvementassistance provided by the government, but also through community social capital, namely through social networksand  community trust norms.  There  is a  strong  relationship between social capital and  solving  various  publicproblems, so that people with higher social capital also have higher awareness, they are able to take collectiveaction in preventing stunting.
Pentingnya Pemberian Asi Eksklusif Untuk Mencegah Stunting Pada Anak
Authors: Efendi Suradi , Sriyanah Nour , Cahyani Andi Suci , Hikma Sri , K Kiswati
Published: December 2021

Stunting is a linear growth disorder that is not appropriate for age. One of the factors causing stunting is not giving exclusive breastfeeding to infants (Sholihah, 2019) . Stunting prevalence A total of 151,398 children in South Sulawesi suffer from stunting or failure to thrive in 2020. They are spread over five districts with the highest stunting rates. Of the 24 regencies/cities in South Sulawesi, there are four regions with the highest stunting rates, namely in Bone Regency 43 percent, Enrekang 39 percent, Jeneponto 36 percent, Takalar 34 percent, and Bantaeng 33 percent (Head of the South Sulawesi Provincial Government Health Service). In the last year, there has been a reduction in the stunting rate of around 7000 cases. Meanwhile, last year, South Sulawesi was still in the top 10 with the highest stunting rate nationally. The goal is that participants are expected to be able to know about the importance of exclusive breastfeeding to prevent stunting in children. The method of community service is the planning, implementation, monitoring and evaluation stages. The target of the implementation of this service is 9 pregnant women. This implementation is assisted by various parties including the Head of Midwifery at the Paccing Health Center, Posyandu midwives and students to carry out community service. The results of community service found that pregnant women will apply it when the baby is born, starting from babies aged 0 to 6 months. The conclusion is that the community service carried out was successful in increasing exclusive breastfeeding to prevent stunting in children at the UPT Puskesmas Paccing Kab. Bone.
Pendidikan Kesehatan (Buku KIA 2020) Khusus Ibu di Masa Pandemi Covid-19 di PMB Bumi Cinta Gorontalo
Authors: Rauf Efri Leny , Katili Dwi Nur Octaviani , Umar Siskawati
Published: December 2021

Knowledge of mothers about the use of Maternal and Child Health (MCH) books, which is still considered only as a health record book for health workers, is an obstacle in shaping the health behavior of pregnant women about the importance of routine pregnancy check-ups, understanding the danger signs of early pregnancy, the importance of taking Fe tablets regularly, as well as daily health care. According to the initial survey of the service team, we see that knowledge and understanding have an impact on the awareness of pregnant women about the contents of the MCH book, especially now that the MCH book has been revised so that the importance of health education on MCH books needs to be explained again in the independent practice of the midwife of the love of Gorontalo. The method of service is through lectures/counseling, discussion and question and answer. As a result of our dedication, we get the enthusiasm of pregnant women in listening to our explanations and asking important things they want to know
Penyuluhan Kesehatan Cegah Stunting dengan Perbaikan Pola Makan, Pola Asuh Dan Sanitasi pada Ibu Hamil di UPT Puskesmas Antang
Authors: Sriyanah Nour , Efendi Suradi , N Nurmaulida , Z Zulfadhilah , R Rahmawati
Published: December 2021

: Stunting is a chronic malnutrition problem caused by lack of nutritional intake for a long time, resulting in growth disorders in children, namely the child's height is lower or shorter (short) than the standard age. The condition of a child's short body is often said to be a hereditary factor (genetic) from both parents, so that many people just accept it without doing anything to prevent it. In fact, as we all know, genetics is a determinant of health that has the least effect when compared to behavioral, environmental (social, economic, cultural, political) factors and health services. In other words, stunting is a preventable problem. Stunting is a growth failure problem experienced by infants under 5 years of age who are malnourished since in the womb until the baby is born. Assessment of stunting nutritional status can be done through anthropometric measurements of TB/U classified through nutritional classification status. Stunting is a condition where the child's height is shorter than the height of children his age. According to UNICEF, stunting occurs in children aged 0 to 59 months with a height below minus (moderate and severe stunting) and minus three (chronic stunting) measured from the WHO child growth standards. In Indonesia, stunting is still a health problem in quite a large number. Based on the 2013 Basic Health Research, around 37.2 percent of Indonesian children under the age of 5 are stunted.
AR-GE HARCAMALARI VE POLİTİKALARINDA SEÇİLİ ÜLKELER VE TÜRKİYE KARŞILAŞTIRMASI
Authors: ELİK Türkan , ATILGAN YAŞA Ayşe
Published: December 2021

Ülkelerin ekonomik kalkınma ve büyümesinde kilit rol oynayan, ulusal ve uluslararası piyasalarda üstünlük sağlayan Araştırma-Geliştirme (Ar-Ge)’nin her geçen gün önemi özel, kamu ve diğer sektörler açısından artış göstermektedir. Bu yöndeki faaliyet alanlarının genişleyebilmesi, Ar-Ge harcamalarının ve performansının artabilmesi için kamunun politika araçları ile müdahalesi gerekliliği oluşmuştur. Bu çalışmada, Ar-Ge harcamaları ve politikalarını başarılı yürüten ülkelerde Ar-Ge harcama ve politikalarının boyutları ve ne şekilde uygulandığı sorgulanmış ve Türkiye’de uygulanabilecek politikaların belirlenmesi amaçlanmıştır. Bu doğrultuda çalışmada, Ar-Ge faaliyetlerine yönelik yapılan harcama ve politikaların seçili ülkeler ve Türkiye’de gelişimi ve uygulamaları incelenmiştir. Ülkelerin seçilmesinde Ar-Ge göstergeleri ve uyguladıkları Ar-Ge politikalarındaki başarıları etkili olmuştur. Yapılan incelemeler doğrultusunda, Ar-Ge harcama yoğunluğu Türkiye dışındaki ülkelerde OECD ülkeleri ortalamasında gerçekleşirken Türkiye’de OECD ortalamasının altında olduğu ve Ar-Ge faaliyet alanlarının arttırılmasında ise politika yapıcıların teşvik destek unsurlarına yönelimi Japonya, Almanya, Güney Kore ve İsviçre’de, ağırlıklı olarak kredi ve hibe gibi vergi dışı; Türkiye’de ise vergisel destekler sağlama yönünde geliştiği saptanmıştır.
İnovasyonun Yenilenebilir Enerji Üretimine Etkisi: IEA Üyesi Ülkeler Üzerine Panel Veri Analizi
Authors: ÇOBAN Mustafa Necati , KANGAL Nalan , EROĞLU İlhan , YETER Fatih
Published: December 2021

Yenilenebilir enerji, fosil yakıtların çevreye verdiği zararların önemli boyutlara gelmesiyle beraber günden güne önemini artırmaktadır. Ülkeler, çevresel sürdürülebilirlik için yenilenebilir enerji üretimlerini artırma yoluna gitmektedirler. Yenilenebilir enerjinin kullanım alanları artsa da halen ülkeler için önemli bir maliyet içerdiği de bilinmektedir. Yenilenebilir enerjinin kullanımına yönelik maliyetlerin azaltılmasında inovasyonların etkisinin önemli olduğu bilinmekte ve inovasyonlar arttıkça yenilenebilir enerji üretiminin artacağı yönünde bir görüş birliği bulunmaktadır. Maliyetlerin azaltılması ile beraber inovasyonun ayrıca enerji verimliliğini artıracağı söylenebilir. İnovasyonların artması ve dolayısıyla yenilenebilir enerji üretiminin artmasının çevre kirliliğinin azaltılmasına önemli katkı sağlayacağı düşünülmektedir.

Bu çalışmada 21 IEA üyesi ülkede inovasyonun yenilenebilir enerji üretimi üzerine etkisinin araştırılması amaçlanmaktadır. İnovasyon göstergesi olarak Küresel İnovasyon Endeksi kullanılmıştır. Bağımlı değişkenin yenilenebilir enerji üretimi (terawatt/saat) olduğu çalışmada ayrıca kişi başına düşen GSYİH ve karbon emisyonu gibi kontrol değişkenleri de dahil edilmiştir. 21 IEA ülkesine ait 2009-2019 yılları arası verilerin kullanıldığı çalışmada dengeli panel veri analizi yapılmıştır. Yapılan analiz sonucunda inovasyonun 21 IEA üyesi ülkede yenilenebilir enerji üretimini artırdığı bulgusuna ulaşılmıştır.
Peran Dan Fungsi Public Relation Dalam Mempertahankan Citra Positif Portal Berita Online Antaranews.Com
Authors: Rolando Dede Mercy , Adellia Tri , Aziz Nuril Maulana Alifia , Wicaksono Galuh Dwi Kartika
Published: December 2021

This study aims to determine how the role and function of Public Relations in LKBN ANTARA Bureau Lampung in maintaining a positive image in the eyes of the public. In order to examine this research, the author uses descriptive qualitative research methods with data collection in the form of interviews, documentation and literature. The subject of this research is Public Relations practitioners in LKBN Anatara Lampung bureau. This study looks at the impact of technological advances that have disrupted conventional mass media, so that news channels are now converged into online channels. However, due to the convenience offered by online media, the information submitted cannot be filtered properly. The amount of information that is anonymous has resulted in the largest number of hoax news in online media. This reduces the credibility of an online news portal in the eyes of the public. Even some people doubt the accuracy of the news available on online channels. Public Relations at LKBN ANTARA Bureau Lampung acts as a Communication Technician, Communication Facilitator and Problem Solving Facilitator. And Public Relations here also acts as a management function and communication function.
Pola Komunikasi PT Apparel One Indonesia Terhadap Produktivitas Karyawan Pada Masa Pandemi Covid-19
Authors: Huda Miftahul , Saputra Viro Dharma , Ningtyas Velani Ayu
Published: December 2021

Abstract

The purpose of this study was to determine the pattern of organizational communication at PT Apparel One Indonesia in order to increase employee productivity during the covid-19 pandemic. This research is a type of qualitative research. Data sources consist of primary and secondary. Data collection techniques using observation, interviews, and documentation. The analysis technique uses data reduction (data reduction), data presentation (data display), and drawing and testing conclusions. From the results of this study, it shows that the downward communication pattern used is the chain communication pattern, employees interacting with the leadership must go through the whatsapp group media. The pattern of leadership communication to employees is very influential on employee work motivation in achieving common company goals. In the upward communication pattern, employees always listen to directions, suggestions, and ideas given by the leadership. It is intended that the workflow within the company can run well. Leaders always provide good feedback to employees by providing input, advice, and providing solutions. In the horizontal communication pattern, harmonious communication between fellow employees is a top priority to avoid misunderstandings and still aims to maintain solid teamwork.

 

Keywords: Communication Pattern, PT. Apparel One Indonesia Semarang, Employee Productivity
CARCINOMA DE URACO PATOLOGIA POCO FRECUENTE: REPORTE DE UN CASO Y REVISION DE LITERATURA
Authors: Velasco Basantes María Augusta , Pazmiño Palacios Juan Bernardo , Rosales Torres Antonio Miguel , Girón Orellana Karen Aileen
Published: December 2021

OBJETIVO: Describir las características, tratamiento y evolución del adenocarcinoma de uraco. MATERIALES Y METODOS: Paciente de 39 años de edad que fue referido de Hospital Regional de Occidente del Área de Salud de Quetzaltenango, por cuadro de hematuria intermitente con impresión diagnostica de carcinoma urotelial de alto grado en estudio patológico en biopsia previa por cistoscopia. Recibiendo tratamiento de quimioterapia sin respuesta. CASO CLÍNICO: Paciente masculino de 39 años, con antecedente de diabetes mellitus tipo II, diagnosticada hace 2 años con tratamiento a base de metformina; que presenta disuria y hematuria intermitente de 1 año de evolución; con 2 cistoscopias que reportan Adenocarcinoma invasor musculo detrusor libre a descartar carcinoma de uraco. Al examen físico del abdomen no hay masas, o adenopatías, Radiografía de tórax normal, TAC abdomen: masa vesical de 8 x 5.5 cm en domo vesical, adherida a pared abdominal. Fue llevado a sala de operaciones donde se realizó resección amplia de uraco más cistectomía parcial con disección inguinal pélvica bilateral. La patología confirma el diagnostico con márgenes libres. Fue enviado a radioterapia y recibió 50 Gys al lecho; al momento del estudio no presenta recurrencias. RESULTADOS: Es una patología poco frecuente por lo que no existe un consenso sobre el tratamiento adyuvante. CONCLUSIONES: La cirugía (cistectomía parcial) más terapia adyuvante con quimioterapia y /o radioterapia están indicados en este tipo de patologías. Es necesario un control y seguimiento riguroso multidisciplinario junto a un amplio plan educacional del paciente y familiares.
TUMOR DE WILMS EN RIÑÓN EN HERRADURA
Authors: Molina Estrada Allan Keithel , González Fernando , Hernández Erwin , Bolaños Javier
Published: December 2021

Introducción: El riñón en herradura es la más común de las anomalías por fusión. Aparece en 1 de cada 400 nacimientos, el tumor de Wilms o Nefroblastoma es el segundo tumor abdominal más frecuente en la edad pediátrica y responde por más del 90 % de los tumores renales en pediatría. El TW es el primer ejemplo de cáncer  en el que se alcanzaron significativas tasas de curación gracias a las terapias multimodales que incluyen quimioterapia, nefrectomía radical y radioterapia. Objetivo: Presentar el caso clínico de un paciente con diagnostico de Riñón en Herradura con presentación inusual de un Tumor de Wilms mediante Nefrectomía radical y quimioterapia pos operatoria mediante el protocolo NTWS 5. Métodos: El reporte de un paciente masculino de 10 años con Tumor de Wilms en un Riñón en Herradura, con revisión y comparación de los protocolos NTWS 5 y S.I.O.P. Resultado: Se logró realizar una Nefrectomía Radical con márgenes quirúrgicos libres de neoplasia sin encontrar metástasis a órganos vecinos. Se administra quimioterapia adyuvante durante 24 semanas con remisión completa de la enfermedad y adecuada función renal. Conclusiones: Los objetivos del tratamiento son lograr una curación completa con una baja toxicidad medicamentosa y conservar una adecuada función renal. La cirugía continúa siendo el pilar del tratamiento, la discusión está enfocada al uso de terapia neoadyuvante o adyuvante y cuáles deben ser los medicamentos y las dosis recomendadas. Todos los pacientes con TW deben recibir Quimioterapia Adyuvante. El uso de radioterapia es indispensable en la mayoría de los casos.
DISLOCACIÓN TESTICULAR. REVISIÓN DE LA LITERATURA. A PROPÓSITO DE UN CASO
Authors: Escobar Gómez Andrés Salvador , Estrada Pazos Carlos Gonzalo , Contreras Morales Luis Alberto , Jo Bonila Mario José
Published: December 2021

OBJETIVO: Presentar el caso clínico de un paciente con dislocación testicular derecha, la cual ameritó exploración inguinal y orquidopexia transescrotal derecha. ANTECEDENTES: La dislocación testicular es poco frecuente, y se han reportado aproximadamente 200 casos en la literatura médica desde su primera descripción en 1818; en Guatemala solamente se cuenta con una publicación respecto al tema, lo que hace que el caso clínico presentado aporte información respecto al tema. MATERIALES Y MÉTODOS: Se presenta el caso con fotografías clínicas, de un paciente joven, quien sufre accidente en motocicleta, contusionando la región genital contra el tanque de gasolina, provocando la dislocación testicular derecha, siendo manejado de forma quirúrgica. RESULTADOS: En los pacientes que se realiza el diagnóstico temprano, presentan adecuada evolución post quirúrgica, sin complicaciones a largo plazo en su seguimiento. CONCLUSIONES: Pese a que es una patología poco frecuente, el aumento del uso de la motocicleta como medio de transporte en nuestro país, predispone a un incremento en las lesiones de los genitales externos.
A Review on Recent Advantages in Algebraic Theory of Neutrosophic Matrices
Authors:   Tishreen University, Department of Mathematics, Syria, Abobala Mohammad ,   Gaziantep University, Department of Mathematics, Turkey,   Gaziantep University, Department of Mathematics, Turkey, Bal Mikail , Hatip Ahmed
Published: December 2021

This work is dedicated to give the reader a wide review for recent advantages in the algebraic study of neutrosophic matrices, refined neutrosophic matrices, and n-refined neutrosophic matrices.
مسئلہ "بیع بالشرط " فقہاءکی آراءاورمعاصرمعیشت کےتناظرمیں تحقیقی وتجزیاتی مطالعہ
Authors: Zubair Tayyab  , Dr. Muhammad Talha Hussain
Published: December 2021

It is a basic role of religion to protect the people’s wealth and property. So, certain rules and disciplines are fixed which secure the public property. A person alone cannot fulfill his requirements. Therefore, Shari’ah adopts the way of sale. In which with their compromise one can use the good or property of the other and can get it in his custody. The matter of sale should be unconditional, but various narrations of Hazrat Muhammad (PBUH) mention buying and selling with a condition. There are different opinions of jurists (Fuqaha) due to different Narrations. They have divided the conditions into several types and briefly explained each of them. The most important of these are those which are customary in society but against the requirements of the contract. This study seeks to answer the question as to which jurist's opinion on the issue is based on convenience and how to adopt it. Therefore, after a thorough investigation of the issue, the views of the jurists have been analyzed in the contemporary situation so that an effective solution can be reached. The purpose of this study is to select a better solution keeping in view the contemporary economy. It is also helpful in the formation of Contemporary Jurisprudence. The research concludes that such a condition should be allowed in view of the modern economy. However, the consent of the parties is required for this. Not only does the Shariah encourage it, but it also facilitates the people, especially the traders.