bluuebunny/crossref_metadata_2025 huggingface dataset:
BRAFnon-V600E more frequently co-occurs with IDH1/2 mutation in adult patients with gliomas than patients harboring BRAFV600E, but without survival advantage
Authors: Da Rong , Wang Maode , Jiang Haitao , Wang Tuo , Wang Wei
Published: March 2021

Background

The effect of BRAFnon−V600E and BRAFV600E on the outcome and the molecular characteristics in adult glioma patients is unknown and needs to be explored, although BRAFV600E has been extensively studied in pediatric glioma.
Methods

Co-occurring mutations and copy number alterations of associated genes in the MAPK and p53 pathways were retrieved and investigated using the cBioPortal. The prognosis of available adult glioma cohorts with BRAFV600E and BRAFnon−V600E mutations was also investigated.
Results

Glioblastoma multiform was the most common cancer type with BRAF non−V600E and BRAFV600E. TP53 (56.00% vs. 7.41%), IDH1/2 (36.00% vs. 3.70%), and ATRX (32.00% vs. 7.41%) exhibited more mutations in BRAFnon−V600E than in BRAFV600E, and TP53 was the independent risk factor (56.00% vs. 7.41%). Both BRAFnon−V600E and BRAFV600E frequently overlapped with CDKN2A/2B homozygous deletions (HD), whereas there was no significant difference. Survival analysis showed no difference between BRAF non−V600E and BRAFV600E cohorts, even excluded the effects of IDH1/2 mutations, and concerned the BRAFnon−V600E mutations in the glycine-rich loop (G-loop) and in the activation segment. The estimated mean survival of BRAFnon−V600E and IDH1/2WT with mutations in the G-loop groups was the shortest.
Conclusions

BRAF non−V600E exhibited a higher association with IDH1/2 mutation than BRAFV600E, but no survival advantage was found.
Construction of a novel immune gene-based model for prognosis prediction of colorectal cancer
Authors: Xie Bin , lin jie
Published: March 2021

Background

Colon adenocarcinoma (COAD) is the third leading cause of cancer-related death. Although surgical treatment and chemotherapy of COAD have made significant progress, its immunotherapy also has great potential, nowadays.
Methods

Gene expression profiles and clinical data of COAD patients were obtained from The Cancer Genome Atlas_Colon Adenocarcinoma (TCGA_COAD) and Gene Expression Omnibus (GEO) databases, which were further detected for immune-related genes. Immune-related genes were downloaded from Immunology Database and Analysis Portal (ImmPort). LASSO Cox regression analysis was utilized to analyze the immune-related prognostic signature. The prognostic value of the signature was validated by ROC curve. To further detected the potential pathway about immune-related genes in COAD patients, Gene Set Enrichment Analysis (GESA) was used to identify the most significant pathways.
Results

Finally, a total of 436 immune-related mRNA were identified. Eleven prognosis-related genes were selected to establish an immune-related prognostic signature, which divided patients into high and low risk groups. Several biological processes, such as immune response was enriched. Moreover, our prognosis model has better performance in predicting the 1-, 3-, 5- and 8-years overall survival (OS) for patients from the TCGA and GEO cohort. Also, the complicated signature obtained by combining immune-related signatures with clinical factors provides a more accurate OS predicting compared with individual molecular signatures.
Conclusion

We have established a prognostic signature consisting of 11 immune-related genes, which may be potential biomarkers for identifying COAD with a high risk of death. Then, the possibility including immunotherapy in personalized COAD treatment was evaluated.
GRNN Model for prediction of groundwater fluctuation in the state of Uttarakhand of India using GRACE data under limited bore well data
Authors: Kumar Dilip , Bhattacharjya Rajib Kumar
Published: March 2021

Springs, the primary source of water in the Indian state of Uttarakhand, are disappearing day by day. A report published by United Nations Development Program in 2015 indicates that due to deforestation, and forest fire, the groundwater of the state has been reduced by 50% between 2007 and 2010. As such, for taking proper adaptation policies for the state, it is necessary to monitor the state's groundwater fluctuation. Unfortunately, the bore well data are very limited. Thus, we are proposing two general regression neural network (GRNN)-based models for fast estimation of groundwater fluctuation. The first model evaluates and predicts the groundwater fluctuation in the five known bore well data districts of the state, and the second model, which is based on the first model along with a correlation matrix, predicts the groundwater fluctuation in the districts where no bore well data are available. The assessment of the results shows that the proposed GRNN-based model is capable of estimating the groundwater fluctuation both in the areas where bore well data are available and the areas where bore well data are not available. The study shows that there is a sharp decline in the groundwater level in the hilly districts of the state.
Feeding preparation strategy for the supercritical water oxidation (SCWO) system for disposing of liquid hazardous waste
Authors: Wang Bo , Lu Meng , Zhao Lixin , Zhang Zhezhou , Zhao Yihua , Qin Songyan
Published: March 2021

Supercritical water oxidation (SCWO) technology has a great potential application for the disposal of liquid hazardous wastes. The feeding process is vital for the safety and normal operation of SCWO. This paper describes the feeding preparation strategy of SCWO with multilevel grouping and programming. Based on the physicochemical properties, the liquid hazardous wastes from various industrial manufacturers were first grouped into acid, neutral and alkaline groups. By mixing between samples, the primary grouping tanks were determined to be acid, alkali, amphoteric reacting, organic and organic high-chlorine liquid wastes. By distributing acid, alkali, amphoteric reacting liquid wastes into organic wastes, three parallel feeding routes are regulated for the homogenizing tank phase, which avoids the reaction between wastes. By calculating with the linear programming optimization model of MATLAB, the waste compatibility ratio of each feeding route was determined to meet the feeding requirements of SCWO. The feeding preparation strategy of this paper provides a practical instruction for the SCWO design and operation.
Onenigheid over een Doopvraag. De Gevolgen van Twee Incidenten in het Amsterdam van 1613 voor de Vormgeving van de Remonstrantse en Contraremonstrantse Doopliturgie
Authors: De Jong Klaas-Willem , Kroese Wouter
Published: March 2021

In this essay, the authors use new primary sources to reconstruct which baptism questions were asked during two services held in Amsterdam in 1613. These services, which were taken by, amongst others, the Reformed ministers P. Plancius and G. van der Heyden and in which the later Remonstrant foremen J. Wtenbogaert and S. Episcopius acted as godparents, caused great turmoil. Research of the various editions of baptismal liturgy reveals three basic types of the second baptism question. Primary and secondary literature have overlooked the significance of one of these types in the Amsterdam services. Wtenbogaert and Episcopius, but especially the latter, were not aware of the existence of all three types and felt misled since they did not want to subscribe to the doctrine taught from the Amsterdam pulpits by affirming the questions posed. The authors outline the impact of the incidents on the format of both later Reformed and later Remonstrant baptismal liturgy.
Electronic Health Record Use in Swiss Nursing Homes and Its Association With Implicit Rationing of Nursing Care Documentation: Multicenter Cross-sectional Survey Study (Preprint)
Authors: Ausserhofer Dietmar , Favez Lauriane , Simon Michael , Zúñiga Franziska
Published: March 2021

BACKGROUND

Nursing homes (NHs) are increasingly implementing electronic health records (EHRs); however, little information is available on EHR use in NH settings. It remains unclear how care workers perceive its safety, quality, and efficiency, and whether EHR use might ease the burden of documentation, thereby reducing its implicit rationing.

OBJECTIVE

This study aims to describe nurses’ perceptions regarding the usefulness of the EHR system and whether sufficient numbers of computers are available in Swiss NHs, and to explore the system’s association with implicit rationing of nursing care documentation.

METHODS

This was a multicenter cross-sectional study using survey data from the Swiss Nursing Homes Human Resources Project 2018. It includes a convenience sample of 107 NHs, 302 care units, and 1975 care workers (ie, registered nurses and licensed practical nurses) from Switzerland’s German- and French-speaking regions. Care workers completed questionnaires assessing the level of implicit rationing of nursing care documentation, their perceptions of the EHR system’s usefulness and of how sufficient the number of available computers was, staffing and resource adequacy, leadership ability, and teamwork and safety climate. For analysis, we applied generalized linear mixed models, including individual-level nurse survey data and data on unit and facility characteristics.

RESULTS

Overall, the care workers perceived the EHR systems as useful; ratings ranged from 69.42% (1362/1962; guarantees safe care and treatment) to 78.32% (1535/1960; allows quick access to relevant information on the residents). However, less than half (914/1961, 46.61%) of the care workers reported sufficient computers on their unit to allow timely documentation. Half of the care workers responded that they sometimes or often had to ration the documentation of care. After adjusting for work environment factors and safety and teamwork climate, both higher care worker ratings of the EHR system’s usefulness (β=−.12; 95% CI −0.17 to −0.06) and sufficient numbers of computers (β=−.09; 95% CI −0.12 to −0.06) were consistently associated with lower implicit rationing of nursing care documentation.

CONCLUSIONS

Both the usefulness of the EHR system and the number of computers available were important explanatory factors for care workers leaving care activities (eg, developing or updating nursing care plans) unfinished. NH managers should carefully select and implement their information technology infrastructure with greater involvement and attention to the needs of their care workers and residents. Further research is needed to develop and implement user-friendly information technology infrastructure in NHs and to evaluate their impact on care processes as well as resident and care worker outcomes.
Internet-Delivered Exposure-Based Therapy for Symptom Preoccupation in Atrial Fibrillation: Uncontrolled Pilot Trial (Preprint)
Authors: Särnholm Josefin , Skúladóttir Helga , Rück Christian , Klavebäck Sofia , Ólafsdóttir Eva , Pedersen Susanne S , Braunschweig Frieder , Ljótsson Brjánn
Published: March 2021

BACKGROUND

Atrial fibrillation (AF) is the most common cardiac arrhythmia in the adult population. AF is associated with a poor quality of life (QoL) and, in many patients, current medical treatments are inadequate in alleviating AF symptoms (eg, palpitations). Patients often present with symptom preoccupation in terms of symptom fear, avoidance, and control behaviors. Internet-delivered cognitive behavior therapy is effective for treating other somatic disorders but has never been evaluated in patients with AF.

OBJECTIVE

The aim of this study is to evaluate the efficacy and feasibility of AF-specific internet-delivered cognitive behavior therapy.

METHODS

We conducted an uncontrolled pilot study in which 19 patients with symptomatic paroxysmal AF underwent internet-delivered cognitive behavior therapy. Participants completed self-assessments at pretreatment, posttreatment, and at a 6-month follow-up along with handheld electrocardiogram measurements with symptom registration. The treatment lasted 10 weeks and included exposure to physical sensations, reduction in avoidance behavior, and behavioral activation.

RESULTS

We observed large within-group improvements in the primary outcome, AF-specific QoL (Cohen d=0.80; P<.001), and in symptom preoccupation (Cohen d=1.24; P<.001) at posttreatment; the results were maintained at the 6-month follow-up. Treatment satisfaction and adherence rates were also high. We observed an increased AF burden, measured by electrocardiogram, at the 6-month follow-up, but a significant decrease was observed in the overestimation of AF symptoms at posttreatment and 6-month follow-up. Exploratory mediation analysis showed that a reduction in symptom preoccupation mediated the effects of internet-delivered cognitive behavior therapy on AF-specific QoL.

CONCLUSIONS

This study presents preliminary evidence for the potential efficacy and feasibility of a novel approach in treating patients with symptomatic AF with internet-delivered cognitive behavior therapy.

CLINICALTRIAL

ClinicalTrials.gov NCT02694276; https://clinicaltrials.gov/ct2/show/NCT02694276
“Comparative study of effect of pre-operative counselling on postoperative pain in patients undergoing elective lower limb orthopaedic surgeries under spinal anaesthesia”. (Preprint)
Authors: Patil Vidya , Mathpati Laxmi , Holyachi Renuka , Dharmarao Pratibha , Devi K Nirmala , Allalmath Santosh , Udgiri Rekha , Patil Aravind
Published: March 2021

BACKGROUND

Background: A thorough pre-operative patient counselling plays a crucial role in the post-operative pain management. The primary objective was to study the effect of pre-operatively educating the patients about pain on the VAS in post-operative period.

OBJECTIVE

: A thorough pre-operative patient counselling plays a crucial role in the post-operative pain management. The primary objective was to study the effect of pre-operatively educating the patients about pain on the VAS in post-operative period.

METHODS

The study was done in 70 ASA grade I and II patients in two groups of 35 each, undergoing elective lower limb orthopaedic surgeries lasting for a period of less than 4 hours under spinal anaesthesia.

RESULTS

There was a statistically significant difference in the mean VAS scores at the 8th, 16th, and 24th hour post-operative period between the study and control groups.

CONCLUSIONS

Pre- operative education on pain helped the pain care team towards better planning of management strategies, and also the patients by reduced post- operative pain and thereby improved their general condition.

CLINICALTRIAL

a ICMR(Indian council of medical research) research project with STS Reference No-2016-02469.
Association of smartphone overuse with refractive errors: baseline findings of the EHCSIR cohort study (Preprint)
Authors: Imani Alireza , Ghasemi Falavarjani Khalil , Soleimani Mohammad , Hoseini Seyedahmad , Motevalian Seyed Abbas
Published: March 2021

BACKGROUND

Uncorrected refractive errors, including myopia, hyperopia, and astigmatism, are among the top causes of visual impairment. Thus, it is of great importance to investigate the underlying risk factors for these refractive errors. However, there is limited inconclusive evidence suggesting that using digital display devices may increase the risk of developing refractive errors.

OBJECTIVE

This study was designed to investigate the possible association between excessive smartphone use and refractive errors.

METHODS

A total of 4886 individuals (3054 females and 1824 males; mean age = 42.63 ± 8.10) participated in this cross-sectional study. Each participant underwent a thorough eye examination in order to investigate whether each individual was suffering from myopia, hyperopia, or astigmatism. To attain information about the pattern of smartphone dependency, "Smartphone Addiction Scale" questionnaire was used. Multivariate analysis using logistic regression was used to compare the groups and explore the association between smartphone addiction and refractive errors.

RESULTS

Of all the participants who underwent the examination, 28.2%, 7.9%, and 37.2% were diagnosed with myopia, hyperopia, and astigmatism, respectively. Age was associated with myopia, hyperopia, and astigmatism; however, higher levels of education was only associated with myopia. After adjustment for age, gender, and level of education, it was demonstrated that severe dependency on smartphones was associated with myopia (adjusted OR: 1.513, CI: 1.128 - 2.028) suggesting that using digital display devices overuse can be associated with myopia. No such association was observed between smartphone usage and hyperopia or astigmatism.

CONCLUSIONS

Based on this study's results, excessive use of smartphones is associated with myopia. Given the fact that refractive errors are a huge burden on the healthcare system and society, it seems that more investigation should be made in order to lessen the harmful impacts of using smartphones especially myopia.
A POTÊNCIA DO SILÊNCIO NA ESCRITA DE CLARICE LISPECTOR: A NEGAÇÃO DA PALAVRA E O DRAMA DA ALTERIDADE
Authors: Côrtes Cristiane
Published: March 2021

O presente artigo pretende refletir sobre as questões relativas ao uso da linguagem na obra da escritora brasileira Clarice Lispector na perspectiva do silêncio e do silenciamento. Para nós, a escritora procura problematizar aquilo que Benedito Nunes considera ser um drama da linguagem, pois, em sua obra, sempre nos apresenta um conflito entre o que se pretende narrar e a impossibilidade de se usar palavras para esse exercício. A autora procura traduzir esse drama a partir das lacunas de representação que seu texto traduz na forma de silêncio e poesia. O artigo pretende desdobrar tal drama em dois aspectos, sendo o primeiro, a incapacidade de representação pela escrita, que jamais deve ser fechada ou elaborada e sim espontânea, performática. O segundo diz respeito ao exercício de alteridade denunciando a impossibilidade de a palavra literária representar a experiência alheia. Para tanto, o último romance publicado em vida, A hora da estrela, será o texto usado como referência de análise, uma vez que carrega abertamente a temática da representação na figura de um narrador personagem, homem letrado, que tenta, em vão, traduzir a experiência da pobre nordestina nas ruas do Rio de Janeiro.
A NARRATIVA DE CLARICE LISPECTOR NO CORAÇÃO SELVAGEM DO BRASIL NO SÉCULO XX: ALGUNS ASPECTOS SOCIOPOLÍTICOS
Authors: Carvalho da Silva Francisco Carlos , Carvalho Geórgia Gardênia Brito Cavalcante
Published: March 2021

O objetivo principal do presente artigo consiste numa breve análise da literatura de Clarice Lispector (1920-1977), especificamente das crônicas “Mineirinho” (1962) e “Carta ao Ministro da Educação” (1968), seguidas da novela A hora da estrela (1977) e dos contos “Felicidade clandestina” (1971) e “A bela e a fera ou a ferida grande demais” (1977). Tendo em vista que a obra literária da autora é ampla e diversa, escolhemos como temáticas a serem analisadas, a presença de alguns aspectos sociopolíticos observáveis na sua produção literária. Analisar a narrativa de Clarice Lispector pelo viés sociopolítico mostra-se relevante, uma vez que, na maioria das vezes, esses elementos são deixados de lado nas análises que são dedicadas à sua obra. Como base teórica, recorremos aos trabalhos de Candido (2000), Lucas (1970), Hobsbawm (1995), Bauman (2015) e Heller (2016) entre outros.
Ketamine as a Sedative for Methotrexate-Induced Neurotoxicity with Added NMDA Antagonism
Authors: Ilahi Zara , Janardhan Shruthi , Dave Manasi , Khariton Megan , Feuer Pamela , Venkataraman Akila , Romanos-Sirakis Eleny
Published: March 2021

MTX is used in the treatment of several childhood cancers and has side
effects of varying severity [1]. Neurotoxicity can occur in up to
15% of patients receiving high-dose MTX [2, 3]. Elevated
homocysteine in CSF are documented in such cases. Dextromethorphan, an
NMDA receptor antagonist, suppresses homocysteine activity and is the
initial treatment. Ketamine, also an NMDA receptor antagonist, may be
considered as an optimal treatment choice in intubated patients
requiring sedation. We describe the use of ketamine in a pediatric
patient with methotrexate-induced neurotoxicity. Ketamine as treatment
of MTX-induced neurotoxicity has not been described in the literature.
Corrigendum
Authors: Editorial E
Published: March 2021

The Editor-in-Chief has been informed that in the article ?Comparisons of
Quantemol and Morgan LXCat cross section sets for electron-neutral
scattering and rate-coefficients: helium and water?, FACTA UNIVERSITATIS,
Series Physics, Chemistry and Technology Vol. 17, No 2, 2019, pp. 145-159,
DOI: https://doi.org/10.2298/FUPCT1902145M, the cross sections for
electron-impact excitation of helium in Figure 1b) are wrongly presented.
The values of the cross section in the ordinate axis are marked in the
interval from 10-1 to 101 (in units 10-16 cm2), and should be from 10-2 to
100. We apologize for that oversight. After further discussion with the
corresponding author, the Editor-in-Chief has decided to publish a
corrigendum with corrected Figure 1. Link to the corrected article:
https://doi.org/10.2298/FUPCT1902145M

 Link to the corrected article 10.2298/FUPCT1902145M
Organic thiocyanates - glucosinolate enzymatic degradation products or artefacts of the isolation procedure?
Authors: Todorovska-Rasic Milica , Radulovic Niko
Published: March 2021

Glucosinolates are abundant in plants of the order Brassicales, and they are
degraded by myrosinases into various organic breakdown products:
isothiocyanates, thiocyanates, nitriles, etc., depending on their structure,
conditions of hydrolysis, the presence of certain protein cofactors. Their
most common hydrolysis products are isothiocyanates, while simple nitriles,
epithionitriles, and thiocyanates are produced occasionally. Organic
thiocyanates are described from a very limited number of Brassicales taxa.
Up to now benzyl, (4-hydroxyphenyl)methyl, (4-methoxyphenyl)methyl, 4-
methylthiobutyl, and allyl thiocyanates were reported as products of
glucosinolates autolysis. The present review summarizes the knowledge on the
mechanism of organic thiocyanate formation from the corresponding
thioglucosides. The enzymatic formation of organic thiocyanates is believed
to be enabled by thiocyanate-forming protein (TFP), but they could be formed
via metabolic routes that do not involve TFP. All of the reported
thiocyanates are produced from stable (carbo)cationic species that allow an
isomerization of an isothiocyanate to thiocyanate, and vice versa. Although
the possibility that thiocyanates can be biosynthesized in plats under
certain conditions cannot be dismissed, allyl thiocyanate can be a thermal
isomerization artefact of the original isothiocyanate that is formed in the
heated zones of the gas chromatograph, while other thiocyanates could form
in an aqueous medium via heterolytic dissociation to ambident nucleophilic
SCN- and its recapture. One should always be aware of this analytical
shortcoming when concluding on the presence and quantity of these specific
(iso)thiocyanantes in the analyzed sample.
Structural, magnetic and up-conversion properties of YF3: Yb/Ln (Ln = Er, Tm, Ho) solid solutions
Authors: Aleksic Jelena , Barudzija Tanja , Mitric Miodrag , Boskovic Marko , Ristic Zoran , Kostic Ljiljana
Published: March 2021

In this paper, we investigated YF3: Yb/Er, YF3: Yb/Tm, and YF3: Yb/Ho solid
solutions prepared by reaction of an appropriate amount of oxides with
ammonium difluoride (NH4HF2) as a fluorinating agent. These samples were
characterized by Xray diffraction (XRD), magnetic measurements, and
up-conversion (UC) photoluminescence spectra. The results show that all
samples are single-phase and crystallize in an orthorhombic crystal
structure of the ?-YF3 structure type. Above 100 K, the measured molar
magnetic susceptibility was fitted by the Curie-Weiss law and the average
effective magnetic moments for the observed samples were obtained. All the
samples showed pure paramagnetic behavior. When doped with lanthanide
elements (Yb/Er, Yb/Tm, Yb/Ho), YF3 solid solutions can emit characteristic
green, red, blue, and near IR light under the excitation of a 980 nm laser
diode.
Pengetahuan dan Keterampilan Bantuan Hidup Dasar Serta Penanganan Tersedak Pada Siswa SMA
Authors: Purnomo Edi , Nur Akbar , A. Pulungan Zulhaini Sartika , Nasir Andi
Published: March 2021

Gawat darurat merupakan suatu kejadian yang terjadi secara mendadak sehingga megakibatkan seseorang memerlukan penanganan dan pertolongan secara cepat dan tepat. Salah satu tindakan yang dapat dilakukan masyarakat awam dan tenaga medis dalam menangani kasus gawat darurat yaitu dengan memberikan Bantuan Hidup Dasar (BHD) dan Basic Life Support (BLS) yang merupakan suatu usaha mencegah terjadinya henti jantung dan henti napas. Tujuan: penelitian ini dilakukan guna untuk mengetahui pengaruh Bantuan Hidup Dasar (BHD) dan penanganan tersedak terhadap peningkatan pengetahuan dan keterampilan siswa SMAN 3 Mamuju. Penelitian ini menggunakan  One-Group pre test-post test design guna untuk mengetahui pengetahuan dan keterampilan dalam penanganan Bantuan Hidup Dasar (BHD) dan penanganan tersedak pada siswa SMAN 3 Mamuju. Subyek yang digunakan dalam penelitian ini adalah siswa SMAN 3 Mamuju dengan total responden sebanyak 35 siswa. Analisis data penelitian menggunakan SPSS dan uji hipotesis menggunakan Paired t-test. Hasil uji statistic dengan Paired t-test terdapat pengaruh signifikan sebelum dan setelah diberikan pelatihan Bantuan Hidup Dasar (BHD) dan penanganan tersedak dengan nilai signifikansi p value=0,001  pengetahuan, keterampilan BHD P Value = 0,002 dan keterampilan penanganan tersedak P Value =0,001 dengan taraf signifikansi 0,05 (P0,05). Kesimpulan Pelatihan Bantuan Hidup Dasar (BHD) dan penanganan tersedak efektif untuk meningkatkan pengetahuan, keterampilan Bantuan Hidup Dasar dan keterampilan penanganan tersedak siswa SMAN 3 Mamuju sehingga diharapkan penanganan kasus gawat darurat yang dapat ditemui dilapangan dapat diatasi dengan cepat dan tepat.
Motivating Students to Learn AI Through Social Networking Sites: A Case Study in Hong Kong
Authors: Ng Tsz Kit , Chu Kai Wa
Published: March 2021

In Hong Kong, after-school activities have long been used to foster friendships and to allow students to pursue their interests in an informal setting. This case study reports on a three-phase action research process in which information technology teachers delivered after-school activities focused on artificial intelligence during the COVID-19 transition to remote learning. Using semi-structured interviews, a motivational questionnaire, and lesson observations, this study describes how extracurricular activities were delivered online using social networking sites and how students perceived the new experience. Our results suggest that, in order to deploy meaningful activities via social media, teachers need to build collaborative environments that facilitate social engagement among students. These findings have implications for new practices in social media and other blended technologies, and can help students strike a healthy balance between their academic and non-academic life during this challenging period.
Moving Assessment Online: Experiences within a School of Pharmacy
Authors: Morgan Kelsey , Adams Erin , Elsobky Teresa Mary , Brackbill Marcia , Darr Amber
Published: March 2021

The COVID-19 pandemic required academic institutions to quickly transition to online learning and make changes to assessment procedures. This study examines how a school of pharmacy creatively approached the challenge of online assessment while maintaining the standards necessary to prepare practice-ready student pharmacists. To conduct traditional exams, instructors deployed two different types of methods utilizing testing software: a video conferencing technology approach which mimicked pre-pandemic, on-campus proctored exams; or open-book, internet access-enabled exams that ensured academic integrity and rigor through various testing strategies. To assess students’ clinical skills, faculty used a combination of techniques such as physical examinations, patient interviews, and patient presentations. To understand the student experience with these assessments, students were surveyed using a 12-item questionnaire. Overall, online video proctoring maintained consistency in exam structure and administration, but required extensive instruction for both students and proctors. Students preferred unproctored, open-book, internet access-enabled, standard time exams versus proctored, closed-book, internet-access disabled, extended time exams. Changes to testing procedures, whether with proctored or unproctored methods, appeared to increase student stress.
The Effect of Subjective Well-Being, Peer Support, and Self-Efficacy on Student Engagement of Class X Students of Four State Senior High School in Sidoarjo [Pengaruh SWB, PS, dan Efikasi Diri terhadap SE Siswa Kelas X di Empat SMAN di Kabupaten Sidoarjo]
Authors: Nurmalita Tania , Yoenanto Nono Hery , Nurdibyanandaru Duta
Published: March 2021

An initial survey showed that school students at the Sekolah Menengah Atas Negeri (SMAN; State Senior High School) level in the Sidoarjo Regency of East Java Province, Indonesia, suffered low levels of student engagement (SE).  This research examined the impact of subjective well-being, peer support, and self-efficacy on the student engagement of the students in the Class 10 of four SMAN in the Sidoarjo Regency. 328 students were involved in this research, filling in a survey related to the four variables of the study.  The results of regression testing indicated that subjective well-being, peer support, and self-efficacy had significant influence on increases in student engagement (SE). The implication of this research was that the efforts by the school, parents, and other parties was related to attention being given, outside of improvement in the quality of the academic atmosphere. Psychological well-being, peer support, as well as increases in self-efficacy, may assist students to become actively involved in the learning process.

 

Survey awal menunjukkan siswa di tingkat Sekolah Menengah Atas (SMA) Kabupaten Sidoarjo memiliki student engagement (SE) yang rendah. Penelitian ini mengkaji dampak dari subjective well-being, peer support, dan efikasi diri terhadap student engagement (SE) pada siswa kelas X yang berasal dari empat Sekolah Menengah Atas Negeri (SMAN) di Kabupaten Sidoarjo. 328 siswa terlibat dalam penelitian ini dengan mengisi survei terkait empat variabel studi. Hasil uji regresi menunjukkan bahwa subjective well-being, peer support, dan efikasi diri memberikan pengaruh signifikan terhadap peningkatan student engagement (SE). Implikasi penelitian ini adalah adanya upaya sekolah, orangtua, dan pihak lain terkait untuk memberikan perhatian di luar peningkatan kualitas atmosfir akademik. Kesejahteraan psikologik, dukungan sosial teman sebaya, maupun peningkatan efikasi diri dapat membantu siswa lebih terlibat aktif dalam proses pembelajaran.
Analysis of the Gas Phase Epitaxy of Silicon Carbide as a Basic Process for Power Elec-tronics Technology. Review
Authors:   Saint Petersburg Electrotechnical University «LETI», Saint-Petersburg, Russia, Afanasev A.V. , Ilyin V.A. ,   Saint Petersburg Electrotechnical University «LETI», Saint-Petersburg, Russia, Luchinin V.V. ,   Saint Petersburg Electrotechnical University «LETI», Saint-Petersburg, Russia, Reshanov S.A. ,   Ascatron AB, Kista – Stockholm, Sweden
Published: March 2021

Currently, chemical gas deposition is the main method for producing high-quality and reproducible epitaxial layers for commercial silicon carbide (SiC) power devices. Based on the experience of ETU «LETI» in the synthesis of monocrystalline SiC, an analysis of the current state of silicon carbide gas phase epitaxy (CVD) technology was carried out. It has been shown that modern CVD reactors allow to implement the growth processes of SiC epitaxial structures of high quality with the following parameters: substrates diameter up to 200 mm; thicknesses of epitaxial layers from 0.1 to 250 μm; layers of n - and p -types conductivity with ranges of doping levels 10-10 cm and 10-10 cm, respectively. At the same time, setting up the technology of the reproducible high-quality growth of epitaxial layers is an individual task for a specific type of reactor. It requires a detailed consideration of the technological factors presented in this paper, which at the end determine the achievable parameters of SiC-epitaxial products
La proxemia en la lectura: cómo se aproximan al texto los lectores de primaria según su edad, contexto y nivel de competencia lectora
Authors: Recio Pineda Sara
Published: March 2021

proxemia, lectura, educación primaria
Stworzenie specjalnych stref ekonomicznych – poważny czynnik restrukturyzacji gospodarki
Authors: Cikało Eugeniusz , Nowosiadło Stefan
Published: March 2021

Głównym celem dzisiejszej polityki regionalnej Ukrainy jest stworzenie prawnych i ekonomicznych warunków dla efektywnego wykorzystania potencjału zasobów każdego regionu, jego umiejscowienia geopolitycznego w oparciu o przeszłość historyczno-kulturową. Jednym z efektywnych mechanizmów terytorialno-gospodarczej organizacji gospodarki, jej restrukturyzacji, rozszerzenia samodzielności regionów jest sformowanie specjalnych stref ekonomicznych (SSE), na terenach których wprowadza się ulgi celne, walutowo-finansowe, podatkowe oraz inne warunki sprzyjające rozwojowi działalności krajowych i zagranicznych osób prawnych i fizycznych
WROCŁAWSKI BUDŻET OBYWATELSKI JAKO NARZĘDZIE DO WZMACNIANIA KAPITAŁU NATURALNEGO I ODPORNOŚCI MIASTA NA ZMIANY KLIMATU W LATACH 2016-2018
Authors: Jamontt Marta Joanna , Kociszewski Karol , Platje Johannes
Published: March 2021

Participatory budgets are a popular form of co-decision of residents about public space and quality of life in the city. Projects submitted to participatory budgets respond to needs such as recreation, health, communication and safety. This article evaluates the projects from 2016-2018 of the Wroclaw Participatory Budget in terms of aspects related to the wider issue of natural capital and climate change. The results obtained indicate that despite increasing financial outlays on projects that can contribute to strengthening environmental and climate aspects, the share of investments directly targeted at their implementation is relatively small. A total of 201 projects were analyzed, of which 12% directly and 18% indirectly referred to issues related to natural capital and/or climate change.
Periodicity and perfect state transfer in quantum walks on variants of cycles
Authors: Barr Katharine E. , Proctor Tim J. , Allen Daniel , Kendon Viv M.
Published: March 2021

We systematically investigated perfect state transfer between antipodal nodes of discrete time quantum walks on variants of the cycles $C_4$, $C_6$ and $C_8$ for three choices of coin operator. Perfect state transfer was found, in general, to be very rare, only being preserved for a very small number of ways of modifying the cycles. We observed that some of our useful modifications of $C_4$ could be generalised to an arbitrary number of nodes, and present three families of graphs which admit quantum walks with interesting dynamics either in the continuous time walk, or in the discrete time walk for appropriate selections of coin and initial conditions. These dynamics are either periodicity, perfect state transfer, or very high fidelity state transfer. These families are modifications of families known not to exhibit periodicity or perfect state transfer in general. The robustness of the dynamics is tested by varying the initial state, interpolating between structures and by adding decoherence.
What Drives Customer Loyalty in Islamic Banking? An Evidence from Pakistan
Authors: Muhammad Umer Quddoos  , Muhammad Asif Shamim  , Muhammad Ramzan Sheikh  , Muhammad Tariq
Published: March 2021

This study investigates the role of customer intimacy, commitment, and trust in increasing their loyalty and mediating role across trust and customer loyalty nexus. A total of 500 questionnaires were disseminated but 404 of these were included for analysis (approx. 81% response rate). The hypotheses were tested through the structural equation modeling technique using smart PLS. The results indicate that trust has a significant nexus with commitment, customer intimacy, and loyalty. Both commitment and customer intimacy have a significant nexus with customer loyalty. The mediation analysis reveals that commitment and customer intimacy act as important mediating variables in the nexus. The research outcome supports the notion that as the level of trust increases the level of intimacy, commitment, and loyalty would tend to increase as well. The results further reveal that customers are devoted towards persistent and continuing association with Islamic banks. Commitment, trust, and customer intimacy prove to be the foundation factors for building and strengthening customer loyalty. It emerges, that in terms of hierarchy, the customer trust needs to be evolved at the initial level consistently followed by customers' intimacy, commitment, and loyalty.
Cognitive Informatics in Emergency Disaster Management Systems
Authors: Bandi Ajay , Fellah Aziz
Published: March 2021

In this research, we investigated the dynamic assignment of resources in emergency and disaster management systems that assists rescuers and responding agencies in effective real-time coordination. We also proposed a communication framework architecture, a com- mon operating picture that keeps all communication activities among various stakeholders and agencies to manage emergency and disaster responses. This spectrum of activities is achieved through a comprehensive analytical emergency disaster management system that fetches locations using Google APIs geospatial data and infrastructures such as Google Maps. Also, we conducted usability testing by applying cognitive informatics principles to our emergency model. Such a model provides several services across several types of disasters and various locations such as monitoring emergencies and disasters, describing incidents, performing triage, accessing databases, analyzing the specific need of rescuers, and providing assistance within the professional role and jurisdiction status of every stake- holder member. We also found a few design issues in selecting the type of the stakeholder, limiting the data accesses to a few stakeholders, and filtering the historical data by triage codes.
A systematic review: what factors predict Post-Traumatic Stress Symptoms in ambulance personnel?
Authors: Brooks Damian , Brooks Rachel
Published: March 2021

 Background: Ambulance personnel are frequently exposed to traumatic accidents, which makes them a high risk for poor mental health. High rates of Post-Traumatic Stress Symptoms (PTSS) have been found within ambulance personnel samples but no review has
been completed to examine the factors that may be implicated in the development of these symptoms. This literature review provides an overview of the factors that predict PTSS in ambulance personnel.

 Methods: A systematic search strategy was
conducted in April 2020 across the following four databases: PsycINFO, PsycARTICLES, MEDLINE and Cumulative Index to Nursing and Allied Health Literature (CINAHL).

 Results: Eighteen papers were included in this review, and the predictive factors
examined were grouped into four categories: coping style, personal factors, environmental factors and organisational factors.

 Conclusions: An array of factors across the four categories were implicated in the development of PTSS, but these tended
to be indicated in only one or two papers. Evidence was found to suggest that dysfunctional coping styles, reduced levels of some personality traits, proximity and nature of the critical incident and high levels of organisation stress can all lead to PTSS. Further research is needed to support
the reliability of findings.
Mobile stroke unit in the UK healthcare system: avoidance of unnecessary accident and emergency admissions
Authors: Phillips Daniel , Grunwald Iris Q. , Walter Silke , Faßbender Klaus
Published: March 2021

 Aims: The aim of the study was to explore the benefit of a mobile stroke unit (MSU) in the UK National Health Service (NHS) for reduction of hospital admissions.

 Methods: Prospective cohort audit observation
with dispatch of the MSU in the East of England Ambulance Service was conducted. Emergency patients categorised as code stroke and headache were included from 5 June to 18 December 2018. Rate of avoided admission to the accident and emergency (A&E) department, rate of admission directly
to target ward and stroke management metrics were assessed.

 Results: In 116 MSU-treated patients, the following diagnoses were made: acute stroke, n = 33 (28.4%); transient ischaemic attacks, n = 13 (11.2%); stroke mimics, n = 32 (27.6%); and
other conditions, n = 38 (32.8%). Pre-hospital thrombolysis was administered to eight of 28 (28.6%) ischaemic stroke patients. Pre-hospital diagnosis avoided hospital admission for 29 (25.0%) patients. As hospital treatment was indicated, 35 (30.2%) patients were directly triaged to the stroke
unit, one patient (0.9%) even directly to the catheter laboratory. Thus, only 50 (43.1%) patients required transfer to the A&E department. Moreover, the MSU enabled thrombolysis with a median dispatch-to-needle time of 42 mins (interquartile range, 40‐60).

 Conclusion: This first deployment of an MSU in the UK NHS demonstrated improved triage decision-making for or against hospital admission and admission to the appropriate target ward, thereby reducing pressure on strained A&E departments.
Teaching as Authentic Practice in the Graduate Student Supervisory Relationship
Authors: Field James , Blackman Galicia , Francois Kaitlyn
Published: March 2021

This article is the outcome of a co-inquiry with students where shared interests about student learning, students as partners, and a hermeneutic lens shaped the main research questions: What are graduate students’ experiences of the supervisory relationship and what happens inside the relationship in terms of learning and student success? We conducted 16 in-depth interviews with graduate students across various departments and programs. From these interviews we theorized that it may be more appropriate to speak of graduate supervision as a practice which produces internal and external goods. We found that it may be more appropriate to speak of the pedagogy as mentoring. We believe our research findings extend understanding of the supervisory relationship, contribute to the concept of teaching, and expand the idea of partnership with students in higher education wherever faculty and students find themselves in supervisory relationships. This is relevant to SoTL because it allowed us to think of the nuances in the word teaching and how supervisory relationships in higher education may need to expand the way we talk about teaching and learning in higher education.
Implementing electronic data collection platform for household surveys in resource-constrained settings
Authors: Premkumar Prasanna Samuel , Ganesan Santhosh Kumar , Pandiyan Balaji , Krishnamoorthy Dhivya Kumari
Published: March 2021

Background

In resource-constrained settings, quality and timeliness of data are the main concerns related to the use of information systems for decision making. Many different tools are available to improve such systems, but their usefulness is only been recently explored. In this paper, we describe our implementation of an electronic platform, open data kit (ODK) for data collection and its feasibility in data management for a population-based household health expenditure survey.

Methods

We evaluated the use of ODK based data collection in households located in two areas (one urban and one rural) in Vellore, Tamil Nadu, India. From each area, we selected a sample of 60 households for piloting the ODK based questionnaires. The household survey questionnaires were programmed using the Microsoft Excel for data collection in the ODK collect android application. The ODK aggregate was used for data storage and data transfer. A team of six field workers was recruited, and trained to use the ODK collect application for survey data collection. After the training, the field workers pilot tested the questionnaires, both in the form of mock surveys and real on-field testing.

Results

Under mock-interviews, there were no significant differences in time –to completion between the six field workers. A total of 60 households participated in field testing that showed field workers were able to complete the questionnaires in a timely manner, (mean 32 minutes (SD=18)) with minimal errors, and all field workers found the ODK form easy to use. There were no major technical issues in the ODK implementation or with electronic devices.

Conclusions

Results from both mock interviews and on-field testing of our data collection platform show the feasibility of using this approach in resource-constrained settings. The approach used to implement, integrate, and test this platform can benefit other health researchers in developing settings intending to move from paper-based methods toward electronic data collection systems.
Strategi Menulis Karya Ilmiah Model Pembelajaran Kolaboratif Berbasis Problem Based Learning pada Mahasiswa Administrasi Bisnis Politeknik Informatika Nasional
Authors: Husni Bt. Salam
Published: March 2021

Penelitian ini bertujuan untuk meningkatkan kemampuan mahasiswa Admnistrasi Bisnis dalam menyusun karya ilmiah. Penelitian ini yakni penelitian deskriptif kualitatif yang berorientasi pada  pendeskripsian kemampuan mahasiswa dalam menulis karya ilmiah Model Pembelajaran Kolaboratif Berbasis Problem Learning. Desain penelitian yang digunakan adalah penelitian tindakan kelas (PTK) menggunakan desain PTK Kemmis dan Taggart. Metode pengumpulan data adalah metode observasi dan metode intropeksi. Teknik pengumpulan data yaitu teknik wawancara, teknis tes pemberian soal dan dokumentasi. Teknik analisis data yang digunakan yakni melakukan empat kali pertemuan setiap siklusnya kemudian menganalisis setiap hasil siklus yang didapatkan. Hasil penelitian ini menunjukkan pendekatan metode kolaboratif dan PBL dalam menulis dan menyusun karya ilmiah dapat meningkatkan pengetahuan mahasiswa Administasi Bisnis. Peningkatan kemampuan dan pemahaman mahasiswa dapat dilihat pada keaktifan dan keantusiasan mahasiswa dalam melakukan kolaboratif. Peningkatan dari segi kualitas tercermin dari produk hasil menulis karya ilmiah pada siklus I, dan II, . Pada siklus I nilai rata-rata 12 dengan persentase 61% untuk aspek bagian awal, 74% untuk aspek bagian isi, 63% bagian notasi ilmiah dan 61% untuk mekanisme penulisan . Pada siklus ke 2 rata-rata nilai yang diperoleh mahasiswa sebesar 16 dengan persentase 77% untuk aspek bagian awal, 80% untuk aspek bagian isi, 85% bagian notasi ilmiah dan 77% untuk mekanisme penulisan.