bluuebunny/crossref_metadata_2025 huggingface dataset:
Large Optical Nonlinearity of the Activated Carbon Nanoparticles Prepared by Laser Ablation
Authors: Orooji Yasin , Ghanbari Gol Hamed , Jaleh Babak , Rashidian Vaziri Mohammad Reza , Eslamipanah Mahtab
Published: March 2021

Carbon nanoparticles (CNPs) with high porosity and great optical features can be used as a luminescent material. One year later, the same group investigated the NLO properties CNPs and boron-doped CNPs by 532 nm and 1064 nm laser excitations to uncover the underlying physical mechanisms in their NLO response. Hence, a facile approach, laser ablation technique, was employed for carbon nanoparticles (CNPs) synthesis from suspended activated carbon (AC). Morphological properties of the prepared CNPs were studied by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). UV-Vis and fluorescence (FL) spectra were used to optical properties investigation of CNPs. The size distribution of nanoparticles was evaluated using dynamic light scattering (DLS). The nonlinear optical (NLO) coefficients of the synthesized CNPs were determined by the Z-scan method. As a result, strong reverse saturable absorption and self-defocusing effects were observed at the excitation wavelength of 442 nm laser irradiation. These effects were ascribed to the presence of delocalized π-electrons in AC CNPs. To the best of our knowledge, this is the first study investigating the NLO properties of the AC CNPs.
Gut Microbiome Prolongs an Inhibitory Effect of Korean Red Ginseng on High-Fat-Diet-Induced Mouse Obesity
Authors: Lee Seo Yeon , Yuk Hyun Gyun , Ko Seong Gyu , Cho Sung-Gook , Moon Gi-Seong
Published: March 2021

Although the anti-obesity effect of Korean red ginseng (Panax ginseng Meyer) has been revealed, its underlying mechanisms are not clearly understood. Here, we demonstrate an involvement of gut microbiome in the inhibitory effect of Korean red ginseng on high-fat-diet (HFD)-induced mouse obesity, and further provides information on the effects of saponin-containing red ginseng extract (SGE) and saponin-depleted red ginseng extract (GE). Mice were fed with either SGE or GE every third day for one month, and their food intakes, fat weights, plasma glucose, and insulin and leptin levels were measured. Immunofluorescence assays were conducted to measure pancreatic islet size. Stools from the mice were subjected to metagenomic analysis. Both SGE and GE attenuated HFD-induced gain of body weight, reducing HFD-induced increase of food intakes and fat weights. They also reduced HFD-increased plasma glucose, insulin, and leptin levels, decreased both fasting and postprandial glucose concentrations, and improved both insulin resistance and glucose intolerance. Immunofluorescence assays revealed that they blocked HFD-induced increase of pancreatic islet size. Our pyrosequencing of the 16S rRNA gene V3 region from stools revealed that both SGE and GE modulated HFD-altered composition of gut microbiota. Therefore, we conclude that Korean red ginseng inhibits HFD-induced obesity and diabetes by altering gut microbiome.
Lifestyle Changes and Determinants of Children’s and Adolescents’ Body Weight Increase during the First COVID-19 Lockdown in Greece: The COV-EAT Study
Authors: Androutsos Odysseas , Perperidi Maria , Georgiou Christos , Chouliaras Giorgos
Published: March 2021

Previous studies showed that the coronavirus disease 2019 (COVID-19) lockdown imposed changes in adults’ lifestyle behaviors; however, there is limited information regarding the effects on youth. The COV-EAT study aimed to report changes in children’s and adolescents’ lifestyle habits during the first COVID-19 lockdown and explore potential associations between changes of participants’ lifestyle behaviors and body weight. An online survey among 397 children/adolescents and their parents across 63 municipalities in Greece was conducted in April–May 2020. Parents self-reported changes of their children’s lifestyle habits and body weight, as well as sociodemographic data of their family. The present study shows that during the lockdown, children’s/adolescents’ sleep duration and screen time increased, while their physical activity decreased. Their consumption of fruits and fresh fruit juices, vegetables, dairy products, pasta, sweets, total snacks, and breakfast increased, while fast-food consumption decreased. Body weight increased in 35% of children/adolescents. A multiple regression analysis showed that the body weight increase was associated with increased consumption of breakfast, salty snacks, and total snacks and with decreased physical activity. The COV-EAT study revealed changes in children’s and adolescents’ lifestyle behaviors during the first COVID-19 lockdown in Greece. Effective strategies are needed to prevent excessive body weight gain in future COVID-19 lockdowns.
The Role of Resveratrol in Liver Disease: A Comprehensive Review from In Vitro to Clinical Trials
Authors: Izzo Carmine , Annunziata Monica , Melara Giuseppe , Sciorio Roberta , Dallio Marcello , Masarone Mario , Federico Alessandro , Persico Marcello
Published: March 2021

Many studies have shown that resveratrol has a lot of therapeutic effects on liver disorders. Its administration can significantly increase the survival rate after liver transplantation, reduce fat deposition and ischemia-induced necrosis and apoptosis in Wistar rats. Resveratrol can provide Liver protection against chemical, cholestatic, and alcohol-mediated damage. It can improve glucose metabolism and lipid profile, reduce liver fibrosis, and steatosis. Additionally, it is capable of altering the fatty acid composition of the liver cells. Resveratrol may be a potential treatment option for the management of non-alcoholic fatty liver disease (NAFLD) due to its anti-inflammatory, antioxidant, and calorie-restricting effects. There are also studies that have evaluated the effect of resveratrol on lipid and liver enzyme profiles among patients with metabolic syndrome (MetS) and related disorders. Based on the extent of liver disease worldwide and the need to find new treatment possibilities, this review critically examines current in vitro and in vivo preclinical studies and human clinical studies related to liver protection.
The Positive Impact of Vitamin D on Glucocorticoid-Dependent Skeletal Muscle Atrophy
Authors: Karnia Mateusz Jakub , Korewo Daria , Myślińska Dorota , Ciepielewski Ziemowit Maciej , Puchalska Monika , Konieczna-Wolska Klaudia , Kowalski Konrad , Kaczor Jan Jacek
Published: March 2021

(1) The study aimed to investigate whether vitamin D3 supplementation would positively affect rats with glucocorticoids-induced muscle atrophy as measured by skeletal muscle mass in two experimental conditions: chronic dexamethasone (DEX) administration and a model of the chronic stress response. (2) The study lasted 28 consecutive days and was performed on 45 male Wistar rats randomly divided into six groups. These included two groups treated by abdominal injection of DEX at a dose of 2 mg/kg/day supplemented with vegetable oil (DEX PL; n = 7) or with vitamin D3 600 IU/kg/day (DEX SUP; n = 8), respectively, and a control group treated with an abdominal injection of saline (CON; n = 6). In addition, there were two groups of rats chronically stressed by cold water immersion (1 hour/day in a glass box with 1-cm-deep ice/water mixture; temperature ~4 °C), which were supplemented with vegetable oil as a placebo (STR PL; n = 9) or vitamin D3 at 600 IU/kg/day (STR SUP; n = 9). The last group was of sham-stressed rats (SHM; n = 6). Blood, soleus, extensor digitorum longus, gastrocnemius, tibialis anterior, and quadriceps femoris muscles were collected and weighed. The heart, liver, spleen, and thymus were removed and weighed immediately after sacrifice. The plasma corticosterone (CORT) and vitamin D3 metabolites were measured. (3) We found elevated CORT levels in both cold water-immersed groups; however, they did not alter body and muscle weight. Body weight and muscle loss occurred in groups with exogenously administered DEX, with the exception of the soleus muscle in rats supplemented with vitamin D3. Decreased serum 25(OH)D3 concentrations in DEX-treated rats were observed, and the cold water immersion did not affect vitamin D3 levels. (4) Our results indicate that DEX-induced muscle loss was abolished in rats supplemented with vitamin D3, especially in the soleus muscle.
Role of Extracellular Mycobacteria in Blood-Retinal Barrier Invasion in a Zebrafish Model of Ocular TB
Authors: Damera Santhosh Kumar , Panigrahi Ranjan Kumar , Mitra Sanchita , Basu Soumyava
Published: March 2021

Intraocular inflammation following mycobacterial dissemination to the eye is common in tuberculosis (TB)-endemic countries. However, the early host–pathogen interactions during ocular dissemination are unknown. In this study, we investigated the early events during mycobacterial invasion of the blood-retinal barriers (BRBs) with fluorescent-tagged Mycobacterium marinum (Mm), host macrophages, and retinal vasculature in a zebrafish model of ocular TB. We found that Mm invaded the vascular endothelium in either the extracellular or intracellular (inside phagocytes) state, typically 3–4 days post-injection (dpi). Extracellular Mm are phagocytosed in the retinal tissue and progress to form a compact granuloma around 6 dpi. Intracellular Mm crossing the BRBs are likely to be less virulent and either persist inside solitary macrophages (in most cases) or progress to loosely arranged granuloma (rarely). The early interactions between mycobacteria and host immune cells can thus determine the course of disease during mycobacterial dissemination to the eye.
First Case of Staphylococci Carrying Linezolid Resistance Genes from Laryngological Infections in Poland
Authors: Michalik Michał , Kosecka-Strojek Maja , Wolska Mariola , Samet Alfred , Podbielska-Kubera Adrianna , Międzobrodzki Jacek
Published: March 2021

Linezolid is currently used to treat infections caused by multidrug-resistant Gram-positive cocci. Both linezolid-resistant S. aureus (LRSA) and coagulase-negative staphylococci (CoNS) strains have been collected worldwide. Two isolates carrying linezolid resistance genes were recovered from laryngological patients and characterized by determining their antimicrobial resistance patterns and using molecular methods such as spa typing, MLST, SCCmec typing, detection of virulence genes and ica operon expression, and analysis of antimicrobial resistance determinants. Both isolates were multidrug resistant, including resistance to methicillin. The S. aureus strain was identified as ST-398/t4474/SCCmec IVe, harboring adhesin, hemolysin genes, and the ica operon. The S. haemolyticus strain was identified as ST-42/mecA-positive and harbored hemolysin genes. Linezolid resistance in S. aureus strain was associated with the mutations in the ribosomal proteins L3 and L4, and in S. haemolyticus, resistance was associated with the presence of cfr gene. Moreover, S. aureus strain harbored optrA and poxtA genes. We identified the first case of staphylococci carrying linezolid resistance genes from patients with chronic sinusitis in Poland. Since both S. aureus and CoNS are the most common etiological factors in laryngological infections, monitoring of such infections combined with surveillance and infection prevention programs is important to decrease the number of linezolid-resistant staphylococcal strains.
Aelurostrongylus abstrusus Infections in Domestic Cats (Felis silvestris catus) from Antioquia, Colombia
Authors: Lopez-Osorio Sara , Navarro-Ruiz Jeffer Leonardo , Rave Astrid , Taubert Anja , Hermosilla Carlos , Chaparro-Gutierrez Jenny J.
Published: March 2021

Although Aelurostrongylus abstrusus infections in domestic cats (Felis silvestris catus) have sporadically been reported in Colombia, there is still no data available on epidemiology nor on the biology of this neglected lungworm parasite. Thus, this epidemiological study aimed to evaluate the occurrence of patent A. abstrusus infections in domestic cats from the Colombian Federal State of Antioquia. In total, 473 fecal samples of indoor/outdoor domestic cats were collected and analyzed thereafter by the Baermann funnel migration technique for the presence of A. abstrusus first stage larvae 1 (L1). The occurrence of A. abstrusus was confirmed in 0.4% (2/473) of investigated cats. Due to the presence of patent A. abstrusus infections in investigated cats, it is unfailing to include this lungworm within differential diagnoses of feline pulmonary disorders. Despite the fact that the Baermann funnel technique is currently the cheapest and the gold standard diagnostic tool for feline aelurostrongylosis, this technique is still unknown by Colombian veterinary surgeons and rarely utilized in small animal veterinary clinics. The current survey intends to generate awareness on this neglected parasitosis and to be considered as a baseline study for future surveys monitoring feline aelurostrongylosis not only in domestic/stray cats but also in endemic wild felid species of Colombia.
From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant Recipient
Authors: Demey Baptiste , Brault Clément , Maizel Julien , Francois Catherine
Published: March 2021

Human adenovirus infection is rare in adult population, except for in immunocompromised individuals. Recipients of allogenic haploidentical hematopoietic stem cell transplantation are reported at high risk for human adenovirus, which is often lethal when it evolves into the disseminated form. Despite existent guidelines, prevention, early diagnosis, and therapeutics remain challenging. Here, we report the case of a fatal evolution of human adenovirus respiratory infection and discuss the actual recommendations to prevent recurrence of this major issue.
The Novel Alpha-2 Adrenoceptor Inhibitor Beditin Reduces Cytotoxicity and Huntingtin Aggregates in Cell Models of Huntington’s Disease
Authors: Singer Elisabeth , Hunanyan Lilit , Melkonyan Magda M. , Weber Jonasz J. , Danielyan Lusine , Nguyen Huu Phuc
Published: March 2021

Huntington’s disease (HD) is a monogenetic neurodegenerative disorder characterized by the accumulation of polyglutamine-expanded huntingtin (mHTT). There is currently no cure, and therefore disease-slowing remedies are sought to alleviate symptoms of the multifaceted disorder. Encouraging findings in Alzheimer’s and Parkinson’s disease on alpha-2 adrenoceptor (α2-AR) inhibition have shown neuroprotective and aggregation-reducing effects in cell and animal models. Here, we analyzed the effect of beditin, a novel α2- adrenoceptor (AR) antagonist, on cell viability and mHTT protein levels in cell models of HD using Western blot, time-resolved Foerster resonance energy transfer (TR-FRET), lactate dehydrogenase (LDH) and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) cytotoxicity assays. Beditin decreases cytotoxicity, as measured by TUNEL staining and LDH release, in a neuronal progenitor cell model (STHdh cells) of HD and decreases the aggregation propensity of HTT exon 1 fragments in an overexpression model using human embryonic kidney (HEK) 293T cells. α2-AR is a promising therapeutic target for further characterization in HD models. Our data allow us to suggest beditin as a valuable candidate for the pharmaceutical manipulation of α2-AR, as it is capable of modulating neuronal cell survival and the level of mHTT.
Identification of Lactate as a Cardiac Protectant by Inhibiting Inflammation and Cardiac Hypertrophy Using a Zebrafish Acute Heart Failure Model
Authors: Haege Elijah R. , Huang Hui-Chi , Huang Cheng-chen
Published: March 2021

Acute heart failure (AHF) commonly arises from decompensated chronic heart failure or sudden structural and functional breakdown causing a decrease in cardiac contractility and consequently fluid accumulation and systemic congestion. Current treatment for AHF aims at reducing fluid overload and improving hemodynamic which results in quick symptom relief but still poor prognostic outcome. This study utilizes a zebrafish AHF model induced by aristolochic acid (AA) to look for natural products that could attenuate the progression of AHF. The project started off by testing nearly seventy herbal crude extracts. Two of the positive extracts were from Chinese water chestnuts and are further studied in this report. After several rounds of chromatographical chemical fractionation and biological tests, a near pure fraction, named A2-4-2-4, with several hydrophilic compounds was found to attenuate the AA-induced AHF. A2-4-2-4 appeared to inhibit inflammation and cardiac hypertrophy by reducing MAPK signaling activity. Chemical analyses revealed that the major compound in A2-4-2-4 is actually lactate. Pure sodium lactate showed attenuation of the AA-induced AHF and inflammation and cardiac hypertrophy suppression as well, suggesting that the AHF attenuation ability in A2-4-2-4 is attributable to lactate. Our studies identify lactate as a cardiac protectant and a new therapeutic agent for AHF.
Inhibiting the Growth of 3D Brain Cancer Models with Bio-Coronated Liposomal Temozolomide
Authors: Perini Giordano , Giulimondi Francesca , Palmieri Valentina , Augello Alberto , Digiacomo Luca , Quagliarini Erica , Pozzi Daniela , Papi Massimiliano , Caracciolo Giulio
Published: March 2021

Nanoparticles (NPs) have emerged as an effective means to deliver anticancer drugs into the brain. Among various forms of NPs, liposomal temozolomide (TMZ) is the drug-of-choice for the treatment and management of brain tumours, but its therapeutic benefit is suboptimal. Although many possible reasons may account for the compromised therapeutic efficacy, the inefficient tumour penetration of liposomal TMZ can be a vital obstacle. Recently, the protein corona, i.e., the layer of plasma proteins that surround NPs after exposure to human plasma, has emerged as an endogenous trigger that mostly controls their anticancer efficacy. Exposition of particular biomolecules from the corona referred to as protein corona fingerprints (PCFs) may facilitate interactions with specific receptors of target cells, thus, promoting efficient internalization. In this work, we have synthesized a set of four TMZ-encapsulating nanomedicines made of four cationic liposome (CL) formulations with systematic changes in lipid composition and physical−chemical properties. We have demonstrated that precoating liposomal TMZ with a protein corona made of human plasma proteins can increase drug penetration in a 3D brain cancer model derived from U87 human glioblastoma multiforme cell line leading to marked inhibition of tumour growth. On the other side, by fine-tuning corona composition we have also provided experimental evidence of a non-unique effect of the corona on the tumour growth for all the complexes investigated, thus, clarifying that certain PCFs (i.e., APO-B and APO-E) enable favoured interactions with specific receptors of brain cancer cells. Reported results open new perspectives into the development of corona-coated liposomal drugs with enhanced tumour penetration and antitumour efficacy.
Phenology and Floret Development as Affected by the Interaction between Eps-7D and Ppd-D1
Authors: Basavaraddi Priyanka A. , Savin Roxana , Bencivenga Stefano , Griffiths Simon , Slafer Gustavo A.
Published: March 2021

Earliness per se (Eps) genes may play a critical role in further improving wheat adaptation and fine-tuning wheat development to cope with climate change. There are only few studies on the detailed effect of Eps on wheat development and fewer on the interaction of Eps with the environment and other genes determining time to anthesis. Furthermore, it seems relevant to study every newly discovered Eps gene and its probable interactions as the mechanisms and detailed effects of each Eps may be quite different. In the present study, we evaluated NILs differing in the recently identified Eps-7D as well as in Ppd-D1 at three temperature regimes (9, 15 and 18 °C) under short day. The effect of Eps-7D on time to anthesis as well as on its component phases varied both qualitatively and quantitatively depending on the allelic status of Ppd-D1 and temperature, being larger in a photoperiod-sensitive background. A more noticeable effect of Eps-7D (when combined with Ppd-D1b) was realised during the late reproductive phase. Consequently, the final leaf number was not clearly altered by Eps-7D, while floret development of the labile florets (florets 2 and 3 in this case, depending on the particular spikelet) was favoured by the action of the Eps-7D-late allele, increasing the likelihood of particular florets to become fertile, and consequently, improving spike fertility when combined with Ppd-D1b.
Genome-Wide Association of Stem Carbohydrate Accumulation and Remobilization during Grain Growth in Bread Wheat (Triticum aestivum L.) in Mediterranean Environments
Authors: Guerra Fernando P. , Yáñez Alejandra , Matus Iván , del Pozo Alejandro
Published: March 2021

Water deficit represents an important challenge for wheat production in many regions of the world. Accumulation and remobilization of water-soluble carbohydrates (WSCs) in stems are part of the physiological responses regulated by plants to cope with water stress and, in turn, determine grain yield (GY). The genetic mechanisms underlying the variation in WSC are only partially understood. In this study, we aimed to identify Single Nucleotide Polymorphism (SNP) markers that account for variation in a suite of WSC and GY, evaluated in 225 cultivars and advanced lines of spring wheat. These genotypes were established in two sites in the Mediterranean region of Central Chile, under water-limited and full irrigation conditions, and assessed in two growing seasons, namely anthesis and maturity growth periods. A genome-wide association study (GWAS) was performed by using 3243 SNP markers. Genetic variance accounted for 5 to 52% of phenotypic variation of the assessed traits. A rapid linkage disequilibrium decay was observed across chromosomes (r2 ≤ 0.2 at 2.52 kbp). Marker-trait association tests identified 96 SNPs related to stem weight (SW), WSCs, and GY, among other traits, at the different sites, growing seasons, and growth periods. The percentage of SNPs that were part of the gene-coding regions was 34%. Most of these genes are involved in the defensive response to drought and biotic stress. A complimentary analysis detected significant effects of different haplotypes on WSC and SW, in anthesis and maturity. Our results evidence both genetic and environmental influence on WSC dynamics in spring wheat. At the same time, they provide a series of markers suitable for supporting assisted selection approaches and functional characterization of genes.
Flow-Through PolyHIPE Silver-Based Catalytic Reactor
Authors: Mravljak Rok , Bizjak Ožbej , Božič Benjamin , Podlogar Matejka , Podgornik Aleš
Published: March 2021

Catalytic reactors performing continuously are an important step towards more efficient and controllable processes compared to the batch operation mode. For this purpose, homogenous high internal phase emulsion polymer materials with an immobilized silver catalyst were prepared and used as a continuous plug flow reactor. Porous material with epoxide groups was functionalized to bear aldehyde groups which were used to reduce silver ions using Tollens reagent. Investigation of various parameters revealed that the mass of deposited silver depends on the aldehyde concentration as well as the composition of Tollens reagent. Nanoparticles formed on the pore surface showed high crystallinity with a cuboctahedra crystal shape and highly uniform surface coverage. The example of the 4-nitrophenol catalytic reduction in a continuous process was studied and demonstrated to be dependent on the mass of deposited silver. Furthermore, productivity increased with the volumetric silver density and flow rate, and it was preserved during prolonged usage and storage.
Mechanical Stabilization of Alginate Hydrogel Fiber and 3D Constructs by Mussel-Inspired Catechol Modification
Authors: Kim Kyoungryong , Choi Jae Hyuk , Shin Mikyung
Published: March 2021

Alginate is a representative biocompatible natural polymer with low cost for a variety of biomedical applications, such as wound dressing, drug delivery systems, tissue scaffolds, and 3D bioprinting. Particularly, the rapid and facile gelation of alginate via ionic interactions with divalent cations has been used for in situ 3D hydrogel fiber formation, which is potentially applicable to engineering cell alignment. However, challenges in enhancing the mechanical properties of alginate hydrogel fibers under physiological conditions are unresolved because of their fast dissociation by ion exchange. Herein, we report a stabilization strategy for alginate hydrogel fibers through mussel-inspired catechol chemistry, which involves inter-catechol crosslinking within a few minutes under basic conditions. The fabrication of catechol-tethered alginate hydrogel fibers through wet-spinning enabled the design of mechanically strong 3D constructs consisting of fibers. Catechol-to-quinone oxidation followed by covalent crosslinking enhanced the tensile strength of a single fiber. Additionally, the ‘gluing’ capability of the catechol stabilized the interface among the fibers, thus retaining the shape fidelity of the 3D constructs and encapsulating the cell density during culture. Our findings will be useful for designing bioink materials specialized in fibrous-type tissue scaffolds with mechanical stability.
Polymeric Hole Transport Materials for Red CsPbI3 Perovskite Quantum-Dot Light-Emitting Diodes
Authors: Tseng Zong-Liang , Lin Shih-Hung , Tang Jian-Fu , Huang Yu-Ching , Cheng Hsiang-Chih , Huang Wei-Lun , Lee Yi-Ting , Chen Lung-Chien
Published: March 2021

In this study, the performances of red CsPbI3-based all-inorganic perovskite quantum-dot light-emitting diodes (IPQLEDs) employing polymeric crystalline Poly(3-hexylthiophene-2,5-diyl) (P3HT), poly(9-vinycarbazole) (PVK), Poly(N,N′-bis-4-butylphenyl-N,N′-bisphenyl)benzidine (Poly-TPD) and 9,9-Bis[4-[(4-ethenylphenyl)methoxy]phenyl]-N2,N7-di-1-naphthalenyl-N2,N7-diphenyl-9H-fluorene-2,7-diamine (VB-FNPD) as the hole transporting layers (HTLs) have been demonstrated. The purpose of this work is an attempt to promote the development of device structures and hole transporting materials for the CsPbI3-based IPQLEDs via a comparative study of different HTLs. A full-coverage quantum dot (QD) film without the aggregation can be obtained by coating it with VB-FNPD, and thus, the best external quantum efficiency (EQE) of 7.28% was achieved in the VB-FNPD device. We also reported a standing method to further improve the degree of VB-FNPD polymerization, resulting in the improved device performance, with the EQE of 8.64%.
Hybrid Models for Efficient Control, Optimization, and Monitoring of Thermo-Chemical Processes and Plants
Authors: Freudenmann Thomas , Gehrmann Hans-Joachim , Aleksandrov Krasimir , El-Haji Mohanad , Stapf Dieter
Published: March 2021

This paper describes a procedure and an IT product that combine numerical models, expert knowledge, and data-based models through artificial intelligence (AI)-based hybrid models to enable the integrated control, optimization, and monitoring of processes and plants. The working principle of the hybrid model is demonstrated by NOx reduction through guided oscillating combustion at the pulverized fuel boiler pilot incineration plant at the Institute for Technical Chemistry, Karlsruhe Institute of Technology. The presented example refers to coal firing, but the approach can be easily applied to any other type of nitrogen-containing solid fuel. The need for a reduction in operation and maintenance costs for biomass-fired plants is huge, especially in the frame of emission reductions and, in the case of Germany, the potential loss of funding as a result of the Renewable Energy Law (Erneuerbare-Energien-Gesetz) for plants older than 20 years. Other social aspects, such as the departure of experienced personnel may be another reason for the increasing demand for data mining and the use of artificial intelligence (AI).
Development of 2,3-Butanediol Production Process from Klebsiella aerogenes ATCC 29007 Using Extracted Sugars of Chlorella pyrenoidosa and Biodiesel-Derived Crude Glycerol
Authors: Lee Ju Hun , Lee Do Yoon , Lee Soo Kweon , Kim Hyeong Ryeol , Chun Youngsang , Yoo Hah Young , Kwak Ho Seok , Park Chulhwan , Lee Ja Hyun , Kim Seung Wook
Published: March 2021

Expectation for renewable energy is increasing due to environmental pollution such as fossil fuel depletion, CO2 emission, and harmful gases. Therefore, in this study, extracted sugars of microalgae, which cause algal blooms and crude glycerol, a biodiesel industry byproduct, were used simultaneously to produce 2,3-BDO. The 2,3-BDO production using only extracted algal sugars was about 4.8 g/L at 18 h, and the production of 2,3-BDO using both extracted algal sugar and crude glycerol was about 7 g/L at 18 h. It was confirmed that the main culture with crude glycerol was increased 1.5-fold compared to the case of using only extracted algal sugars. In addition, four components of the main medium (ammonium sulfate, casein hydrolysate, yeast extract, and crude glycerol) were statistically optimized and the concentrations of the medium were 12, 16, 12, and 13 g/L, respectively. In addition, the final 2,3-BDO production was about 11g/L, which 1.6-fold higher than before the optimization process. As a result, it was confirmed that 2,3-BDO production is possible through the simultaneous use of algal sugars and crude glycerol, which can greatly contribute to the development of zero-waste processes.
Green Synthesis of A Novel MXene–CS Composite Applied in Treatment of Cr(VI) Contaminated Aqueous Solution
Authors: Wan Hongyou , Nan Lan , Geng Huikai , Zhang Wei , Shi Huanhuan
Published: March 2021

The considerable amount of Cr(VI) pollutants in the aqueous environment is a significant environmental concern that cannot be ignored. A series of novel Mxene–CS inorganic–organic composite nanomaterials synthesized by using the solution reaction method was applied to treat the Cr(VI) contaminated water. The Mxene–CS composites were characterized through SEM (scanning electron microscope), XRD (X–ray diffraction), XPS (X–ray photoelectron spectroscopy), and FTIR (Fourier transform infrared). The XRD patterns (observed at 2θ of 18.1°, 35.8°, 41.5°, and 60.1°) and the FT–IR spectra (-NH2 group for 1635 and 1517 cm−1, and -OH group for 3482 cm−1) illustrated that CS was successfully loaded on the Mxene. The effects of solution pH, the dosage of Mxene–CS, and duration time on the adsorption of Cr(VI) by synthesized Mxene–CS were investigated. The removal efficiency of Cr(VI) was increased from 12.9% to 40.5% with Mxene–CS dosage ranging from 0.02 to 0.12 g/L. The adsorption process could be well fitted by the pseudo–second–order kinetics model, indicating chemisorption occurred. The Langmuir isotherm model could be better to describe the process with a maximum adsorption capacity of 43.1 mg/g. The prepared novel Mxene–CS composite was considered as an alternative for adsorption of heavy metals from wastewater.
Energy Recovery from Invasive Species: Creation of Value Chains to Promote Control and Eradication
Authors: Nunes Leonel J. R. , Rodrigues Abel M. , Loureiro Liliana M. E. F. , Sá Letícia C. R. , Matias João C. O.
Published: March 2021

The use of biomass as an energy source presents itself as a viable alternative, especially at a time when the mitigation of climate change requires that all possibilities of replacing fossil fuels be used and implemented. The use of residual biomass also appears as a way to include in the renewable energy production system products that came out of it, while allowing the resolution of environmental problems, such as large volumes available, which are not used, but also by the elimination of fuel load that only contributes to the increased risk of rural fires occurrence. Invasive species contribute to a significant part of this fuel load, and its control and eradication require strong investments, so the valorization of these materials can allow the sustainability of the control and eradication processes. However, the chemical composition of some of these species, namely Acacia dealbata, Acacia melanoxylon, Eucalyptus globulus, Robinia pseudoacacia and Hakea sericea, presents some problems, mainly due to the nitrogen, chlorine and ash contents found, which preclude exclusive use for the production of certified wood pellets. In the case of Eucalyptus globulus, the values obtained in the characterization allow the use in mixtures with Pinus pinaster, but for the other species, this mixture is not possible. From a perspective of local valorization, the use of materials for domestic applications remains a possibility, creating a circular economy process that guarantees the sustainability of operations to control and eradicate invasive species.
Interreligious Dialogue Groups Enabling Human Agency
Authors: Campdepadrós-Cullell Roger , Pulido-Rodríguez Miguel Ángel , Marauri Jesús , Racionero-Plaza Sandra
Published: March 2021

Evidence has shown that interreligious dialogue is one of the paths to build bridges among diverse cultural and religious communities that otherwise would be in conflict. Some literature reflects, from a normative standpoint, on how interreligious dialogue should be authentic and meaningful. However, there is scarce literature on what conditions contribute to this dialogue achieving its desirable goals. Thus, our aim was to examine such conditions and provide evidence of how interreligious dialogue enables human agency. By analyzing the activity of interreligious dialogue groups, we document the human agency they generate, and we gather evidence about the features of the conditions. For this purpose, we studied four interreligious dialogue groups, all affiliated with the United Nations Educational, Scientific and Cultural Organization’s (UNESCO) Association for Interreligious Dialogue (AUDIR), employing in-depth interviews and discussion groups. In these groups, which operate in diverse and multicultural neighborhoods, local actors and neighbors hold dialogues about diversity issues. In so doing, social coexistence, friendship ties, and advocacy initiatives arise. After analyzing the collected data, we conclude that for interreligious dialogue to result in positive and promising outputs, it must meet some principles of dialogic learning, namely equality of differences, egalitarian dialogue, cultural intelligence, solidarity, and transformation.
Mission-Long Recalibrated Science Quality Suomi NPP VIIRS Radiometric Dataset Using Advanced Algorithms for Time Series Studies
Authors: Cao Changyong , Zhang Bin , Shao Xi , Wang Wenhui , Uprety Sirish , Choi Taeyoung , Blonski Slawomir , Gu Yalong , Bai Yan , Lin Lin , Kalluri Satya
Published: March 2021

Suomi NPP has been successfully operating since its launch on 28 October 2011. As one of the major payloads, along with microwave and infrared sounders (Advanced Technology Microwave Sounder (ATMS), Cross-track Infrared Sounder (CrIS)), and ozone mapping/profiling (OMPS) instruments, the Visible Infrared Imaging Radiometer Suite (VIIRS) has performed for well beyond its mission design life. Its data have been used for a variety of applications for nearly 30 environmental data products, including global imagery twice daily with 375 and 750 m resolutions, clouds, aerosol, cryosphere, ocean color and sea-surface temperature, a number of land products (vegetation, land-cover, fire and others), and geophysical and social economic studies with nightlights. During the early days of VIIRS operational calibration and data production, there were inconsistencies in both algorithms and calibration inputs, for several reasons. While these inconsistencies have less impact on nowcasting and near real-time applications, they introduce challenges for time series analysis due to calibration artifacts. To address this issue, we developed a comprehensive algorithm, and recalibrated and reprocessed the Suomi NPP VIIRS radiometric data that have been produced since the launch. In the recalibration, we resolved inconsistencies in the processing algorithms, terrain correction, straylight correction, and anomalies in the thermal bands. To improve the stability of the reflective solar bands, we developed a Kalman filtering model to incorporate onboard solar, lunar, desert site, inter-satellite calibration, and a deep convective cloud calibration methodology. We further developed and implemented the Solar Diffuser Surface Roughness Rayleigh Scattering model to account for the sensor responsivity degradation in the near infrared bands. The recalibrated dataset was validated using vicarious sites and alternative methods, and compared with independent processing from other organizations. The recalibrated radiometric dataset (namely, the level 1b or sensor data records) also incorporates a bias correction for the reflective solar bands, which not only addresses known calibration biases, but also allows alternative calibrations to be applied if so desired. The recalibrated data have been proven to be of high quality, with much improved stability (better than 0.3%) and accuracy (by up to 2%). The recalibrated radiance data are now available from 2012 to 2020 for users and will eventually be archived on the NOAA CLASS database.
Hyperspectral Parallel Image Compression on Edge GPUs
Authors: Ferraz Oscar , Silva Vitor , Falcao Gabriel
Published: March 2021

Edge applications evolved into a variety of scenarios that include the acquisition and compression of immense amounts of images acquired in space remote environments such as satellites and drones, where characteristics such as power have to be properly balanced with constrained memory and parallel computational resources. The CCSDS-123 is a standard for lossless compression of multispectral and hyperspectral images used in on-board satellites and military drones. This work explores the performance and power of 3 families of low-power heterogeneous Nvidia GPU Jetson architectures, namely the 128-core Nano, the 256-core TX2 and the 512-core Xavier AGX by proposing a parallel solution to the CCSDS-123 compressor on embedded systems, reducing development effort, compared to the production of dedicated circuits, while maintaining low power. This solution parallelizes the predictor on the low-power GPU while the entropy encoders exploit the heterogeneous multiple CPU cores and the GPU concurrently. We report more than 4.4 GSamples/s for the predictor and up to 6.7 Gb/s for the complete system, requiring less than 11 W and providing an efficiency of 611 Mb/s/W.
Semi-/Weakly-Supervised Semantic Segmentation Method and Its Application for Coastal Aquaculture Areas Based on Multi-Source Remote Sensing Images—Taking the Fujian Coastal Area (Mainly Sanduo) as an Example
Authors: Liang Chenbin , Cheng Bo , Xiao Baihua , He Chenlinqiu , Liu Xunan , Jia Ning , Chen Jinfen
Published: March 2021

Coastal aquaculture areas are some of the main areas to obtain marine fishery resources and are vulnerable to storm-tide disasters. Obtaining the information of coastal aquaculture areas quickly and accurately is important for the scientific management and planning of aquaculture resources. Recently, deep neural networks have been widely used in remote sensing to deal with many problems, such as scene classification and object detection, and there are many data sources with different spatial resolutions and different uses with the development of remote sensing technology. Thus, using deep learning networks to extract coastal aquaculture areas often encounters the following problems: (1) the difficulty in labeling; (2) the poor robustness of the model; (3) the spatial resolution of the image to be processed is inconsistent with that of the existing samples. In order to fix these problems, this paper proposes a novel semi-/weakly-supervised method, the semi-/weakly-supervised semantic segmentation network (Semi-SSN), and adopts 3 data sources: GaoFen-2 image, GaoFen-1(PMS)image, and GanFen-1(WFV)image with a 0.8 m, 2 m, and 16 m spatial resolution, respectively, and through experiments, we analyze the extraction effect of the model comprehensively. After comparing with other the-state-of-art methods and verifying on an open remote sensing dataset, we take the Fujian coastal area (mainly Sanduo) as the experimental area and employ our method to detect the effect of storm-tide disasters on coastal aquaculture areas, monitor the production, and make the distribution map of coastal aquaculture areas.
Eleven Years of Mangrove–Mudflat Dynamics on the Mud Volcano-Induced Prograding Delta in East Java, Indonesia: Integrating UAV and Satellite Imagery
Authors: Beselly Sebrian Mirdeklis , van der Wegen Mick , Grueters Uwe , Reyns Johan , Dijkstra Jasper , Roelvink Dano
Published: March 2021

This article presents a novel approach to explore mangrove dynamics on a prograding delta by integrating unmanned aerial vehicle (UAV) and satellite imagery. The Porong Delta in Indonesia has a unique geographical setting with rapid delta development and expansion of the mangrove belt. This is due to an unprecedented mud load from the LUSI mud volcanic eruption. The mangrove dynamics analysis combines UAV-based Structure from Motion (SfM) photogrammetry and 11 years (2009–2019) satellite imagery cloud computing analysis by Google Earth Engine (GEE). Our analysis shows unique, high-spatiotemporal-resolution mangrove extent maps. The SfM photogrammetry analysis leads to a 3D representation of the mangrove canopy and an estimate of mangrove biophysical properties with accurate height and individual position of the mangroves stand. GEE derived vegetation indices resulted in high (three-monthly) resolution mangrove coverage dynamics over 11 years (2009–2019), yielding a value of more than 98% for the overall, producer and consumer accuracy. Combining the satellite-derived age maps and the UAV-derived spatial tree structure allowed us to monitor the mangrove dynamics on a rapidly prograding delta along with its structural attributes. This analysis is of essential value to ecologists, coastal managers, and policymakers.
Effects of Bark Beetle Outbreaks on Forest Landscape Pattern in the Southern Rocky Mountains, U.S.A.
Authors: Rodman Kyle C. , Andrus Robert A. , Butkiewicz Cori L. , Chapman Teresa B. , Gill Nathan S. , Harvey Brian J. , Kulakowski Dominik , Tutland Niko J. , Veblen Thomas T. , Hart Sarah J.
Published: March 2021

Since the late 1990s, extensive outbreaks of native bark beetles (Curculionidae: Scolytinae) have affected coniferous forests throughout Europe and North America, driving changes in carbon storage, wildlife habitat, nutrient cycling, and water resource provisioning. Remote sensing is a crucial tool for quantifying the effects of these disturbances across broad landscapes. In particular, Landsat time series (LTS) are increasingly used to characterize outbreak dynamics, including the presence and severity of bark beetle-caused tree mortality, though broad-scale LTS-based maps are rarely informed by detailed field validation. Here we used spatial and temporal information from LTS products, in combination with extensive field data and Random Forest (RF) models, to develop 30-m maps of the presence (i.e., any occurrence) and severity (i.e., cumulative percent basal area mortality) of beetle-caused tree mortality 1997–2019 in subalpine forests throughout the Southern Rocky Mountains, USA. Using resultant maps, we also quantified spatial patterns of cumulative tree mortality throughout the region, an important yet poorly understood concept in beetle-affected forests. RF models using LTS products to predict presence and severity performed well, with 80.3% correctly classified (Kappa = 0.61) and R2 = 0.68 (RMSE = 17.3), respectively. We found that ≥10,256 km2 of subalpine forest area (39.5% of the study area) was affected by bark beetles and 19.3% of the study area experienced ≥70% tree mortality over the twenty-three year period. Variograms indicated that severity was autocorrelated at scales < 250 km. Interestingly, cumulative patch-size distributions showed that areas with a near-total loss of the overstory canopy (i.e., ≥90% mortality) were relatively small (<0.24 km2) and isolated throughout the study area. Our findings help to inform an understanding of the variable effects of bark beetle outbreaks across complex forested regions and provide insight into patterns of disturbance legacies, landscape connectivity, and susceptibility to future disturbance.
Assimilation of LAI Derived from UAV Multispectral Data into the SAFY Model to Estimate Maize Yield
Authors: Peng Xingshuo , Han Wenting , Ao Jianyi , Wang Yi
Published: March 2021

In this study, we develop a method to estimate corn yield based on remote sensing data and ground monitoring data under different water treatments. Spatially explicit information on crop yields is essential for farmers and agricultural agencies to make well-informed decisions. One approach to estimate crop yield with remote sensing is data assimilation, which integrates sequential observations of canopy development from remote sensing into model simulations of crop growth processes. We found that leaf area index (LAI) inversion based on unmanned aerial vehicle (UAV) vegetation index has a high accuracy, with R2 and root mean square error (RMSE) values of 0.877 and 0.609, respectively. Maize yield estimation based on UAV remote sensing data and simple algorithm for yield (SAFY) crop model data assimilation has different yield estimation accuracy under different water treatments. This method can be used to estimate corn yield, where R2 is 0.855 and RMSE is 692.8kg/ha. Generally, the higher the water stress, the lower the estimation accuracy. Furthermore, we perform the yield estimate mapping at 2 m spatial resolution, which has a higher spatial resolution and accuracy than satellite remote sensing. The great potential of incorporating UAV observations with crop data to monitor crop yield, and improve agricultural management is therefore indicated.
Evaluating Alternative Flight Plans in Thermal Drone Wildlife Surveys—Simulation Study
Authors: Witczuk Julia , Pagacz Stanisław
Published: March 2021

The rapidly developing technology of unmanned aerial vehicles (drones) extends to the availability of aerial surveys for wildlife research and management. However, regulations limiting drone operations to visual line of sight (VLOS) seriously affect the design of surveys, as flight paths must be concentrated within small sampling blocks. Such a design is inferior to spatially unrestricted randomized designs available if operations beyond visual line of sight (BVLOS) are allowed. We used computer simulations to assess whether the VLOS rule affects the accuracy and precision of wildlife density estimates derived from drone collected data. We tested two alternative flight plans (VLOS vs. BVLOS) in simulated surveys of low-, medium- and high-density populations of a hypothetical ungulate species with three levels of effort (one to three repetitions). The population density was estimated using the ratio estimate and distance sampling method. The observed differences in the accuracy and precision of estimates from the VLOS and BVLOS surveys were relatively small and negligible. Only in the case of the low-density population (2 ind./100 ha) surveyed once was the VLOS design inferior to BVLOS, delivering biased and less precise estimates. These results show that while the VLOS regulations complicate survey logistics and interfere with random survey design, the quality of derived estimates does not have to be compromised. We advise testing alternative survey variants with the aid of computer simulations to achieve reliable estimates while minimizing survey costs.