bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-term Evolution of Tightly Packed Stellar Black Holes in AGN Disks: Formation of Merging Black Hole Binaries via Close Encounters
Authors: Li Jiaru , Lai Dong , Rodet Laetitia
Published: August 2022

We study the long-term evolution of two or more stellar black holes (BHs) on initially separated but unstable circular orbits around a supermassive BH (SMBH). Such a close-packed orbital configuration can naturally arise from BH migrations in the AGN disk. Dynamical instability of the orbits leads to recurring close encounters between two BHs, during which the BH separation r
p becomes less than the Hill radius
R

H. In rare very close encounters, a tight merging BH binary can form with the help of gravitational wave emission. We use N-body simulations to study the time evolution of close encounters of various degrees of closeness. For a typical “SMBH+2BH” system, the averaged cumulative number of close encounters (with r
p ≲
R

H) scales approximately as ∝ t
0.5. The minimum encounter separation r
p follows a cumulative distribution P(<r
p) ∝ r
p for r
p ≪
R

H. We obtain a semi-analytical expression for the averaged rate of binary captures that lead to BH mergers. Our results suggest that close-packed BHs in AGN disks may take a long time (≳107 orbits around the SMBH) to experience a sufficiently close encounter and form a bound binary. This time can be shorter if the initial BH orbits are highly aligned. The BH binary mergers produced in this scenario have high eccentricities when entering the LIGO band and broad distribution of orbital inclinations relative to the original AGN disk. We explore the effects of the gas disk and find that simple gas drags on the BHs do not necessarily lead to an enhanced BH binary capture rate.
New Detections of Phosphorus Molecules toward Solar-type Protostars
Authors: Wurmser Serena , Bergner Jennifer B.
Published: August 2022

Phosphorus is a necessary element for life on Earth, but at present, we have limited constraints on its chemistry in star- and planet-forming regions; to date, phosphorus carriers have only been detected toward a few low-mass protostars. Motivated by an apparent association between phosphorus molecule emission and outflow shocking, we used the IRAM 30 m telescope to target PN and PO lines toward seven solar-type protostars with well-characterized outflows and firmly detected phosphorus molecules in three new sources. This sample, combined with archival observations of three additional sources, enables the first exploration of the demographics of phosphorus chemistry in low-mass protostars. The sources with PN detections show evidence for strong outflow shocks based on their H2O 110–101 fluxes. On the other hand, no protostellar properties or bulk outflow mechanical properties are found to correlate with the detection of PN. This implies that gas-phase phosphorus is specifically linked to shocked gas within the outflows. Still, the PN and PO line kinematics suggest an emission origin in postshocked gas rather than directly shocked material. Despite sampling a wide range of protostellar properties and outflow characteristics, we find a fairly narrow range of source-averaged PO/PN ratios (0.6–2.2) and volatile P abundances as traced by (PN+PO)/CH3OH (∼1%–3%). Spatially resolved observations are needed to further constrain the emission origins and environmental drivers of the phosphorus chemistry in these sources.
Spectral Rotational Characterization of the Didymos System prior to the DART Impact*
Authors: Ieva Simone , Mazzotta Epifani E. , Perna D. , Dall’Ora M. , Petropoulou V. , Deshapriya J. D. P. , Hasselmann P. H. , Rossi A. , Poggiali G. , Brucato J. R. , Pajola M. , Lucchetti A. , Ivanovski S. L. , Palumbo P. , Corte V. Della , Zinzi A. , Rivkin A. S. , Thomas C. A. , de León J. , Dotto E. , Amoroso M. , Bertini I. , Capannolo A. , Cotugno B. , Cremonese G. , Tana V. Di , Gai I. , Impresario G. , Lavagna M. , Meneghin A. , Miglioretti F. , Modenini D. , Pirrotta S. , Simioni E. , Simonetti S. , Tortora P. , Zannoni M. , Zanotti G.
Published: August 2022

The smallest member of the Didymos binary near-Earth object system (Dimorphos) is the target of the DART/LICIACube mission, the first attempt to change the orbit of another celestial body via a kinetic impactor. It is important to characterize the unperturbed system prior to the DART impact. In this work we obtained, for the first time, spectral characterization of the system at several rotational phases from TNG+DOLORES in the visible range (0.34–0.81 μm). This is crucial in order to disentangle the primary and secondary bodies and highlight eventual dishomogeneities on their surfaces. We confirm that a subtle but persistent spectral variability appears, even when compared with data obtained from previous 2003 and 2019 apparitions. While the reason for such variability is still under investigation, our analysis hints that different compositions could play a role. Future observations during the brighter 2022 apparition in synergy with data obtained from LUKE on board LICIACube will definitely tackle this conundrum.
Quelle(s) géographie(s) de l’éducation ? Plaidoyer pour une approche in-disciplinée de l’éducation en géographie
Authors: Giband David , Nafaa Nora , Delage Aurélie
Published: August 2022

Cet article dresse un panorama inédit diachronique et international du champ de la géographie de l’éducation. Il souligne le rapport tardif, complexe et incomplet que les géographes entretiennent avec l’éducation. La géographie de l’éducation naît dans les années 1960-1970 de façon échelonnée et relativement cloisonnée en France et en Allemagne, puis en Grande Bretagne et en Amérique du Nord. Initialement peu conceptuelle, la géographie de l’éducation connaît un tournant décisif dans les années 2000 avec l’intégration des enjeux développés par les tournants critiques et culturels pris par la géographie dans son ensemble, en lignée directe des approches héritées du tournant spatial. En retour, la géographie intègre les questionnements proposés par l’éducation. Cet article questionne la nature des géographies de l’éducation actuelles, aussi bien dans les pays anglophones, germanophones, qu’en France. Il s’achève sur un plaidoyer pour une approche interdisciplinaire de la géographie de l’éducation.
La lettre morte des coopérations interrégionales dans la mégarégion parisienne
Authors: Gouin Nathan
Published: August 2022

L’aire d’influence de Paris, en raison de son poids économique et démographique, dépasse les frontières administratives de l’Île-de-France, plus petite région française. De ce fait, pour répondre aux nombreux enjeux se posant à l’échelle mégarégionale, différentes tentatives de coopération interrégionale ont eu lieu depuis les années 1960 (livres blancs du Bassin parisien, contrats de plan interrégionaux…). En dehors de quelques exceptions, elles sont toutes restées lettre morte. L’objectif de cet article est de retracer les différentes initiatives de coopérations interrégionales dans le Bassin parisien et d’analyser pourquoi elles n’ont pas abouti. Cette analyse permet de montrer que l’absence de concrétisation de ces initiatives de coopération est due en grande partie à l’incapacité des acteurs institutionnels régionaux à dépasser leurs frontières administratives pour penser et agir à l’échelle mégarégionale. Dernièrement, la réforme de la carte régionale semble compliquer encore davantage les coopérations, qui s’opèrent d’ailleurs actuellement uniquement au niveau de l’Axe Seine, et sonner la fin du Bassin parisien en tant que périmètre d’action publique.
L’« allergie » à Durkheim : Raymond Aron et l’épisode de son élection au Collège de France
Authors: Birnbaum Pierre
Published: August 2022

Raymond Aron a souvent insisté sur ses réserves théoriques à l’égard de la sociologie durkheimienne qu’il considérait comme holiste, et sur sa préférence pour la sociologie de l’action de Max Weber qu’il estimait davantage tournée vers l’histoire et la politique. Dès lors, nous souhaitons d’abord revenir sur la réception, plus que critique, des écrits d’Aron par les héritiers de Durkheim. On se propose ensuite d’analyser le contexte historique et intellectuel de son élection au Collège de France, en avril 1970, où il succède à plusieurs durkheimiens comme Marcel Mauss dont il refuse la conception de la nation considérée comme un tout. On examine les votes successifs des membres du Collège, leurs prises de position, le rôle important dévolu à Claude Lévi-Strauss, et le ralliement final d’Aron à une sociologie durkheimienne à l’égard de laquelle il confesse s’être montré plein d’« injustice ».
Santé et ressources de chômeurs organisés versus accompagnés
Authors: Althaus Virginie , Thouroude Laurence
Published: August 2022

Le chômage, comme le travail en emploi, est traversé d’une ambivalence, entre réduction des atteintes à la santé, générées par l’activité professionnelle, et confrontation à des épreuves qui caractérisent cette période d’entre-deux. Cette recherche vise ainsi à éclairer les relations entre chômage et santé perçue, sous l’angle des activités investies par les chômeurs. L’hypothèse qui la sous-tend est que la santé des chômeurs serait meilleure pour ceux qui tentent – au moyen de diverses activités, notamment, ici, militantes – de s’ancrer dans un réseau social et, ainsi, de bénéficier de ressources pour traverser cet entre-deux. Nous avons réalisé des entretiens individuels et semi-directifs avec douze chômeurs (neuf femmes, trois hommes). Six d’entre eux appartenaient à un collectif de chômeurs organisés et les six autres étaient accompagnés dans le cadre d’un dispositif de retour à l’emploi. Leurs discours ont été comparés au moyen d’une analyse thématique du contenu. Cette analyse met en évidence les similitudes des épreuves vécues et décrites par les participants (stigmatisation, humiliation…), mais elle souligne aussi la diversité des ressources mobilisées selon l’appartenance à l’un ou l’autre groupe.
L’armée française en Afghanistan (2001-2012). L’illusion de la pacification
Authors: Lafaye Christophe
Published: August 2022

L’Afghanistan marque pour l’armée française le retour des combats de haute intensité. Entre 2001 et 2014, 70 000 soldats s’y rendent, faisant de ce théâtre d’opération un véritable creuset pour une nouvelle génération du feu après celle de la guerre d’Algérie. Engagée au sein de la Force internationale d’assistance et de sécurité (FIAS), l’armée de Terre redécouvre entre 2009 et 2011 les combats de contre-insurrection. Elle développe une approche de la pacification centrée sur la population entre 2009 et 2010 avant de basculer dans des combats de haute intensité, préambule au retrait.
Écrire en guerre, Écrire la guerre. Ego-documents des légionnaires italiens pendant la guerre d’Indochine
Authors: Terzoli Mariella
Published: August 2022

À travers l’étude des sources autobiographiques, l’article analyse la complexité de l’expérience de guerre vécue par les légionnaires italiens employés en Indochine. La conscience de la nouveauté et du caractère unique de l’expérience de la guerre, ainsi que la nostalgie d’affections lointaines, ont poussé certains légionnaires à écrire des lettres, des journaux intimes – parfois rédigés après la guerre –, des mémoires. Les récits individuels nous permettront d’accéder aux souvenirs et de comprendre la centralité de cette expérience dans la vie du combattant, constituant pour ceux qui racontent ainsi que pour leurs familles un véritable turning point . Il s’agit donc de réfléchir à des parcours individuels étant pertinents non seulement pour leurs aspects subjectifs, mais aussi en ce qui concerne leur inscription dans le contexte plus large des changements sociaux et politiques de l’histoire italienne et française de l’après-guerre.
« Au milieu de l’étant » avec Heidegger. À l’approche du Geviert
Authors: Souq Pierre
Published: August 2022

Vers 1935, après Être et temps , le concept de « milieu » ( Mitte ) apparaît de deux façons chez le philosophe allemand Martin Heidegger. Sur un plan horizontal, il se trouve, par-delà le « monde ambiant » ( Umwelt ), à l’intersection de l’homme et des dieux, où c’est le poète qui l’incarne à partir du langage ; selon une dimension verticale, il montre un « saut » ( Sprung ) à l’entre-deux du monde et de la terre. En nous appuyant notamment sur la pensée des Beiträge (1936-1940), nous comprenons alors le « milieu » ( Mitte ) comme le centre du Geviert (le Quadriparti) qui permet de localiser « l’être le là » ( Das Da-sein ), à « l’entre-deux » ( Das Zwischen ) du monde et de la terre, mais aussi de l’homme et des dieux. Se faisant, nous sortons de la représentation commune d’une croix ou d’un carré, comme le Geviert semble le dire, pour ouvrir un cercle où la pensée demeure en quête de l’Être.
An efficient algorithm for the numerical evaluation of pseudo differential operator with error estimation
Authors: Pandey Amit K. , Tripathi Manoj P. , Singh Harendra , Rao Pentyala S. , Kumar Devendra , Baleanu D.
Published: August 2022

In this paper we introduce an efficient and new numerical algorithm for evaluating a pseudo differential operator. The proposed algorithm is time saving and fruitful. The theoretical as well as numerical error estimation of the algorithm is established, together with its stability analysis. We have provided numerical illustrations and established that the numerical findings echo the analytical findings. The proposed technique has a convergence rate of order three. CPU time of computation is also listed. Trueness of numerical findings are validated using figures.
Learning communities promote pedagogical metacognition in higher education faculty
Authors: Tocco Audrey J. , Mehrhoff Lauren A. , Osborn Haley M. , McCartin Lyda F. , Jameson Molly M.
Published: August 2022

Pedagogical metacognition, or the reflective and reflexive actions associated with teaching practice, strengthens the planning, monitoring, evaluation, and adjustment of teaching in higher education faculty. Learning communities are optimal environments to foster this active teaching reflection. This study incorporated pedagogical metacognition into a faculty learning community curriculum and explored its impacts on higher education instructors’ reflective and reflexive practices. Faculty participants completed monthly metacognitive reflections for one academic year, each corresponding to a research-based principle of learning. Qualitative analysis indicated that faculty learning community participants recognized their lack of pedagogical training, successfully reflected on their teaching strategies, identified areas for improvement, and set goals to incorporate research-based strategies into their instruction. To maximize student learning, pedagogical metacognition should be included in higher education professional development to encourage reflection on and action upon one’s teaching.
Beyond the Working Age: Labour Supply of Elderly Men and Women in Sri Lanka
Authors: Nilmini P. G. N. , Samaraweera G. R. S. R. C.
Published: August 2022

The aging population, due to the increasing life expectancy and decreasing fertility rates as a result of the demographic transition in Sri Lanka, has created a number of challenges within the labour market. Elders re-entering the labour market is a common phenomenon in countries with rapid population ageing due to the lack of funding for the welfare of the elderly population. The main objective of this research is to compare the gender-based factors affecting Sri Lanka’s elderly labour supply. Secondary data of the Sri Lanka Labour Force Survey (2018) was used for this study, while three Logit Regression models were used for the analysis on labour supply decision making, using 5,897 males, 7,325 females and 13,222 of total elders above the age of 60 years as samples.
According to this research, being in the provinces other than the Western Province and the non-urban sector caused a positive impact on elderly men’s employment. Similarly, it also revealed that age, marital status, being uneducated or only possessing primary education caused a positive impact on elderly women’s employment. Having children, household size has been non-Sinhala have negative impact on elderly labour supply. Finally, policy recommendations have been made to address the issues of the elderly labour supply in the two aspects of social welfare and institutional reforms of the labour market.
Trend analysis in seroprevalence of dengue, chikungunya and malaria: A seven-year serological study from a tertiary care hospital of Maharashtra, India
Authors: Palewar Meghna S , Joshi Suvarna , Yanamandra Sushma , Pol Sae , Dedwal Ashwini , Anand Ankita , Sadafale Ashish , Karyakarte Rajesh
Published: August 2022

Background & objectives:

Dengue, chikungunya and malaria are mosquito-borne infections, which have shared endemicity and similar clinical presentation. Simultaneous co-infection with more than one infectious agent complicates the diagnosis and further course of treatment. This study aims to determine the seroprevalence and trend of malaria, dengue and chikungunya from 2014–2020 in a tertiary care hospital of western India.

Methods:

The present study was retrospective descriptive record-based. Serum samples from clinically suspected dengue and chikungunya were subjected to both IgM antibody capture ELISA kits produced by National Institute of Virology (NIV), Pune, India. They were also subjected to ELISA based NS1Ag testing. In Suspected malaria cases, blood collected in EDTA tubes was subjected for Rapid Malaria antigen testing. Statistical analysis was performed using MS Excel and JMP Software.

Results:

Seropositivity of malaria was comparatively higher in 2014 (5.53%) and a decreasing trend was observed in subsequent years. Majority of malarial infections were caused by Plasmodium vivax (81.67%). There is drastic increase in seropositivity of chikungunya from 2016 (23.67%) and thereafter as compared to 2014 (6.57%) and 2015 (7.29%) indicating its re-emergence. The dengue seropositivity in 2019 (40.19%) was highest in last seven years. Males were predominantly affected, and most affected age group was 21–30 years. Peak transmission was observed in post-monsoon seasons. Dengue and chikungunya co-infection was observed to be 5.79%.

Interpretation & conclusion:

This study emphasizes the importance of surveillance studies to understand the trend of vector-borne diseases for prompt diagnosis, management of patients in hospital setup and for early detection and curtailment of outbreaks and epidemics by public health sectors through appropriate vector control programs.
Abandoned boats contribute to spread of Aedes and Culex vector mosquitoes in coastal belt, Galle District, Southern Sri Lanka
Authors: Dissanayake Dinithi Shamalee , Wijekoon Chandana Dammika , Wegiriya Hemantha
Published: August 2022

Background & objectives: Although, the number of considerable cases of dengue and lymphatic filariasis have been reported from Galle District, Sri Lanka in the past several years, contribution of abandoned boats to spread vector mosquitoes of Aedes and Culex in the coast is not well studied. Our aim was to assess the positive composition of different types of abandoned boats by larval vector mosquitoes to investigate their occurrence and habitat preference, and the monsoonal and co-existence variation of Aedes mosquitoes.

Methods: The 4th instar larvae of Aedes and Culex species from three different abandoned boat types in nine subsampling sites at three municipal areas in Galle District were collected during 2017–2019. In total, 15 sampling rounds were conducted in each site for three years duration as five sample rounds per year. Larval collections and identifications were carried out using standard techniques and identification keys according to WHO guidelines. The occurrence of mosquito larvae was analysed by boat type, locations within area and year. Further, the average infestation variation of Aedes mosquitoes were compared with monsoonal and co-existence changers.

Results; Out of the total abandoned boats, majority (51%) were engine boats and, 32.7%, 16.35% were troller boats and canoe boats, respectively. Troller boats were highly infested boat type for vector mosquitoes. Aedes albopictus was the dominant vector in abandoned boats other than recorded Ae. aegypti and Culex quinquefasciatus. Culex quinquefasciatus showed comparatively low infestation percentages. The average infestation of Ae. albopictus showed a consistent pattern with monsoon variation. A competitive rapid invasion of Aedes aegypti was observed with the suppressing Ae. albopictus in abandoned boats after 2018.

Interpretation & conclusion: Abandoned boats contribute noteworthy to spread of Aedes and Culex vector mosquitoes in coastal belt, Galle District. These study findings would be helpful for researchers and health authorities to design appropriate vector control measures and to mitigate future dengue and filariasis outbreaks.
Clinical Characteristics, Etiology, Recanalization Rates and Neurological Outcomes in CVT
Authors: Jain Rajendra Singh , PV Sripadma , Tejwani Shankar
Published: August 2022

Background:

Recanalization rates in cerebral venous thrombosis (CVT) and its effect on neurological outcome have been debated worldwide and are inadequately addressed in studies from India. Our objective was to study the clinical profile of CVT and determine recanalization rates with its predictors and its effect on outcome.

Methods:

A prospective single centre cohort study on 101 patients with radiologically confirmed acute CVT between October 2018 and June 2021 was conducted. Anticoagulation was given for 3-12 months or lifelong for thrombophilias. Recanalization status of vessels was assessed between 3-6 months and at 12 months after ictus. Outcome was defined as favorable (mRS 0-1) or unfavorable. Patients with atleast one CT/MR venogram on follow up were included.

Results:

Of the 101 enrolled patients, 83 completed study protocol. Mean age of patients was 34.2 ± 11.7 years. Clinical characteristics included headache (75.9%),seizure (66.2%), altered mentation(20.4%) with clustering of cases during summers. Transverse- sigmoid sinuses were predominantly involved (66.2 %) followed by superior sagittal sinus (SSS,65.0%).Commonest etiologies were thrombophilia (27.7%) and postpartum state (15.6%). Complete recanalization was achieved in 67.4%, partial in 26.5% and no recanalization in 6.02% at end of 12 months. Recanalization rates improved from 83.09% between 3-6 months to 93.9 % at 12 months. Median time to last follow-up was 12months and at last follow up 95.1% had favorable mRS with recurrence in two patients with raised factor VIII levels.

Conclusion:

Recanalization occurred in more than 90% of CVT patients. Isolated superior sagittal sinus thrombosis and age <50 years were predictors of complete recanalization. Most patients, except few achieved a favorable mRS.
Adiponectin to Leptin Ratio and its Association with Insulin Resistance in Women with Polycystic Ovarian Syndrome
Authors: Mishra Pragya , Mittal Pratima , Rani Anita , Bharti Rekha , Agarwal Varsha , Suri Jyotsna
Published: August 2022

Background:

Adiponectin and leptin play a major role in metabolic homeostasis. Adiponectin to Leptin ratio can be used as an indicator of insulin resistance and a marker of polycystic ovarian syndrome (PCOS). The study was planned to compare serum adiponectin, leptin, and adiponectin to leptin ratio in age and BMI matched women with and without PCOS and to find out the association of adiponectin to leptin ratio with Insulin resistance in these women.

Methods:

It was a cross-sectional study done in the Gynecology outpatient clinic in a tertiary care center. A total of 120 women, 60 with PCOS and 60 age and BMI matched women without PCOS, who presented in the clinic after the index cases were enrolled and tested for serum adiponectin, leptin, and insulin sensitivity. The main outcome measures were serum levels of adiponectin, leptin, adiponectin to leptin ratio, oral glucose tolerance test, serum insulin and HOMA-IR.

Results:

PCOS women had lower serum Adiponectin, higher serum Leptin level and lower Adiponectin to Leptin ratio compared to non PCOS women, 2.15 ± 3.07 ng/ml vs 10.7 ± 27.91 ng/ml, P < 0.0001; 24.25 ± 16.5 ng/ml vs 13.89 ± 11.19 ng/ml, P = 0.0003 and 0.15 ± 0.24 vs 3.03 ± 15.04, P < 0.0001, respectively. Plasma glucose 2 hours after 75 gm glucose and serum Insulin was significantly increased in PCOS women (108.78 ± 10.22 mg/dl vs 100.18 ± 4.89 mg/dl, P = 0.001 and 5.7 ± 9.53 mU/ml vs 3.02 ± 5.34 mU/ml, P = 0.02, respectively). The mean values of fasting plasma glucose and HOMA-IR were comparable in both groups, P = 0.145, P = 0.719, respectively. There was no significant association of A/L Ratio with BMI, plasma glucose 2 hours after 75 gm glucose, serum Insulin and HOMA-IR, in these women, r = -0.074, P = 0.5754; r = -0.203, P = 0.12; r = -0.018, P = 0.8915; and r = -0.041, P = 0.757, respectively.

Conclusion:

Adiponectin to leptin ratio is significantly reduced in women with PCOS but has no association with insulin resistance.
An Observational Study showing Dipeptidyl Peptidase-4 (DPP-4) Activity and Gene Expression Variation in Chronic Liver Disease (CLD) Patients from a Tertiary Care Hospital of Eastern India
Authors: Barkondaj Bikramjit , Nargis Titli , Chakrabarti Partha , Mukhopadhyay Satinath , Biswas Kalidas , Ganguly Dipyaman , Chaterjee Chandan , Sengupta Nilanjan , Hazra Avijit
Published: August 2022

Introduction:

The studies in animal models of cirrhosis suggest that dipeptidyl peptidase type 4 (DPP-4) enzymes play a crucial role in disease pathogenesis. In this clinical observational study, activity of DPP-4 and related gene expression were analysed in chronic liver disease patients.

Objectives:

To understand the DPP-4 enzyme activity variation in the common types of chronic liver disease by assessing plasma and peripheral blood mononuclear cell (PBMC) DPP-4 activity and comparing with healthy controls and to explore DPP-4 gene expression in PBMC.

Methods:

We recruited 130 study subjects in four cohorts—46 nonalcoholic fatty liver disease (NAFLD), 23 non-alcoholic cirrhosis (NAC) excluding viral aetiology, 21 alcoholic liver disease (ALC), and 40 control subjects. Blood samples were analysed for relevant biochemical parameters and plasma DPP-4 activity. PBMC fraction was used for the DPP-4 activity assay and gene expression analysis.

Results:

We found that lower plasma DPP-4 activity among patient cohorts but this was not statistically significant. The PBMC DPP-4 activity was significantly lower in NAFLD cohort. In the same cohort, DPP-4 gene expression in PBMC fraction was significantly increased (P < 0.05). There was significant correlation between plasma DPP-4 activity and liver injury marker alanine aminotransferase (ALT) among NAFLD (rho = 0.459, P < 0.01), NAC (rho = 0.475, P < 0.05), and ALC (rho = –0.572, P < 0.01) patients. Plasma DPP-4 activity modestly predicted ALT plasma level (beta coefficient = 0.489, P < 0.01).

Conclusions:

The PBMC DPP-4 activity and DPP-4 gene expression gets significantly altered in NAFLD patients. Plasma DPP-4 activity also shows correlation with ALT levels in CLD patients. The role of DPP-4 in disease pathology in NAFLD and other forms of CLD needs to be explored.
Factors Determining Risk Categories in Differentiated Thyroid Carcinoma
Authors: Chirayath Shiga Rappai , Menon Usha V. , Nair Vasantha , Kumar Harish , Praveen VP , Bhavani Nisha , Abraham Nithya
Published: August 2022

Introduction:

Differentiated thyroid carcinoma/cancer (DTC) burden in developing countries could be different from that of the developed nations.

Aims and Objectives:

To describe the clinicopathological characteristics in a cohort of DTC patients in a south Indian state of Kerala and to compare with the data from other centres.

Materials and Methods:

A retrospective analysis of the data collected on DTC patients, from January 2010 to August 2018, attending thyroid cancer clinic at a tertiary care centre.

Results:

mong the 944 patients (male 262; female 682; mean age 43.8 years; standard deviation, SD 13.8), types of tumour were as follows: classical papillary thyroid carcinoma (cPTC) 48.3%, follicular variants of PTC (FVPTC) 28.8%, follicular and hurthle cell carcinoma (FTC&HCC) 10.1%. Mean size of the tumour was 2.7 cm (SD 1.8) papillary thyroid micro carcinomas (PTMC) were seen in 113 patients (12%), which were detected incidentally. Metastases were present at diagnosis in 40.2% cases, most common site being cervical lymph nodes. Distant metastases were seen in 113 patients (14.5%) and commonest site was bone. The American Thyroid Association (ATA) risk stratification was possible only in 684 subjects and showed 31.3% low risk, 41.8% intermediate risk and 26.9% at high-risk category. Lymph node metastasis and distant metastasis were the commonest determining factors for intermediate and high-risk category, respectively. High-risk category was significantly higher in patients >55 years, tumour size >4 cm, FTC/HCC tumour type and extranodal extension (ENE) of lymph node metastasis. Radio active iodine ablation was given to 85.2% subjects.

Conclusion:

In our DTC population, FVPTC formed the second most common type and PTMC were all incidentalomas. Metastasis at diagnosis was higher suggesting delayed presentation. Old age, FTC/HCC, large size of the tumour, ENE were significantly higher in high-risk patients. Rest of the features of these cohort was comparable with the United States cohort of DTC patients.
Clear-Cell Variant of Ameloblastic Carcinoma: Pathological Insights for a more Specific Categorization
Authors: Aggarwal Dipanshu , Jain Anshi , Farnaz Huma , Shetty Devi Charan
Published: August 2022

The presence of clear cells is associated with the aggressiveness of the lesion and also poses a diagnostic dilemma. Hence, specific categorization of the lesion is of the utmost importance for therapeutic intervention. A 70-year-old male patient reported with a chief complaint of discomfort and swelling in the left mandibular alveolar region. Biopsy from the lesion was suggestive of ameloblastic carcinoma (AC) with clear-cell differentiation. The differential diagnosis of clear-cell components can be clear-cell odontogenic carcinoma, clear-cell adenocarcinoma of the salivary gland, mucoepidermoid carcinoma, and metastatic neoplasm. In the present case, the pathogenesis of this rare tumor is studied with the help of molecular markers such as p53, proliferating cell nuclear antigen, alpha-smooth muscle actin, vimentin, and p63 along with special stains such as periodic acid-Schiff, mucicarmine, and alcian blue. The clinical and biological behavior of these lesser-known variants has not been established due to the scarcity of meta-analysis and systematic reviews. Thus, this rare case of AC with clear-cell differentiation would highlight the pathogenesis, prognosis, and outcome of the disease with unusual histological presentation than conventional AC.
Fibrolipoma of the Buccal Mucosa in a Geriatric Patient
Authors: Chhetri Priyanka , Nandini D. B. , Singh Koijam Sashikumar , Banerjee Sumita
Published: August 2022

Lipoma is the most common mesenchymal tumor seen in the trunk and extremities. It is rarely found in the mouth. Clinically, it resembles other lesions and is not considered in the initial diagnosis. Histopathological evaluation is needed for accurate diagnosis. Surgical excision is the main treatment modality. Histologically, many variants are described of which fibrolipoma is thought to have some recurrence. This article describes a case of fibrolipoma of the buccal mucosa in a geriatric patient.
Successful Treatment of Early-Onset Morganella morganii Sepsis in an Extremely Low Birth Weight Infant
Authors: Chang Chia-Ning , Chen Shyi-Jou , Wang Chih-Chien , Lo Wen-Tsung
Published: July 2022

Morganella morganii is a rare cause of neonatal infections, and early-onset neonatal sepsis caused by M. morganii is serious and even fatal. We describe an extremely low birth weight female infant with early-onset M. morganii sepsis to highlight the importance of awareness of this potentially fatal organism.
Liushu-based Instruction and Its Effects on the Motivation and Intended Learning Efforts: The Case of Laos Learners of Standard Chinese
Authors: Guo Qingli , Chew Fong Peng
Published: July 2022

This study examines the effects of Liushu-based instruction on the motivation and intended learning efforts. Beginners of Standard Chinese from Laos were assigned to the experiment group and the control group. The Liushu-based instruction in the experiment group was carried on for ten weeks. It was found that Liushu-based instruction has a positive effect on learners’ motivation, especially for Standard Chinese learners’ Ideal L2 Self and L2 learning experience. In addition, Ideal L2 Self showed a mediation effect between Liushu-based instruction and intended learning efforts. The article also provides several suggestions for the use of Liushu in Chinese character teaching.
Exceptions vs. Non-exceptions in Sound Changes: Morphological Condition and Frequency
Authors: Liu Sha
Published: July 2022

This paper takes an approach different from most previous studies by firstly comparing exceptions with non-exceptions in the diphthongization of [i] to [ei] in Mandarin (AD 1324–Present) to locate factors that explain exceptions. Then it focuses solely on non-exceptional morphemes in this process by comparing morphemes at the forefront of this process with those undergoing it later to examine factors to explain morphemes leading this sound change. Statistical analysis shows that morphemes with the highest frequency among all related morphemes tend to be exceptions to diphthongization of [i] to [ei], and morphemes with high frequency among those non-exceptional morphemes tend to undergo this process earlier. In addition, the factor of frequency change, a proposal of this paper, is statistically significantly correlated with morphemes that lead diphthongization. The morphological condition has been rejected as statistically significant both for explaining exceptions to sound change and leading morphemes in sound change.
Features of cytokine status of the newborns with seizures
Authors: Gurbanova G. M. , Ragimova Naila J. qızı
Published: August 2022

The aim of the present study was to assess the level of cytokines in newborn children of various gestational terms with seizures. A prospective, comprehensive study of 307 newborns of various gestational ages with seizures was carried out.

Evaluation of anamnestic data, antenatal, intrapartum risk factors with using statistical methods showed that mothers of newborns (respectively, full-term and premature) with seizures had a high percentage of extragenital diseases (31.83.7% 2 = 15.4, p = 0.009, vs 62.35.0% 2 = 27.2, p1 0.001), gynecological disorders (49.13.6% 2 = 37.1 p 0.001, and 47.05.1% 2 = 9.69 p1 = 0.046), threatened miscarriage (9.12.5% 2 = 11.290 p 0.001, and 28.54.7% 2 = 14.779 p1 0.001), anemia of pregnancy (40.03.6% 2 = 14.9 , p 0.001 vs 66.44.3% 2 = 18.9, p 0.001). After EEG examination, we found that in most cases, 78 (30.0%) newborns exhibited polymorphic convulsions, i.e. a combination of different types of convulsions. The atypical convulsions were reported in 64 (24.5%) newborns, with a predominance of preterm infants 61 (40.4%). Clonic seizures were more common in full-term infants (n = 34; 30.9%) and preterm (n = 26; 17.2%). Myoclonic convulsions were found mainly in preterm newborns 21% (13.9%). Tonic convulsions were found in only 5 cases (5.3%). According to neurosonographic data, brain swelling was reported in 83 (31.8%), ventriculomegaly in 44 (16.9%), ventriculitis in 43 (16.5%), intraventricular hemorrhage in 66 (15.3%) newborns of the main group. In the control group, periventricular hemorrhage was observed in 37 (14.2%) newborns. Frequency of these disorders in preterm infants was 18.6% higher than in full-term infants (2 = 13.3; p = 0.004). Altered immunological reactivity in newborns with seizures manifested as abnormal cytokine status and significantly elevated pro-inflammatory cytokines (IL-1, 1.9-fold; IL-6, 3-fold; TNF 3.3-fold increase) compared with newborns of control group. Increased concentration of pro-inflammatory cytokines in newborns with HIE is associated with maintenance of seizure activity and aggravates further unfavorable neurological outcome. The cerebral disorders and dysfunction of different organs and systems were found to correlate with immune parameters. Hence, the expression of pro-inflammatory cytokines may be used as a screening marker in diagnostics and prediction of neonatal seizures in presence of perinatal hypoxic-ischemic lesions of the central nervous system.
The Impact of Gender Equality on Green Innovation
Authors: Lin Xi-Li , Yin Hua-Tang
Published: July 2022

Employing a panel of 166 economies covering 1996 – 2018, we investigate the impact of gender equality on green innovation. Our findings indicate that an improvement in gender equality improves green innovation performance. This result is supported by a series of robustness tests. Additionally, we also find that this positive effect tends to be higher in economies with violent conflicts.
The Correlation Between Screen Size and Visibility of Renewable Energy Structures in Online Acceptance Studies: The Case of Wind Turbines
Authors: Ladenburg Jacob , Campbell Kiri
Published: July 2022

The correlation between screen size and visualisations of wind turbines in an internet survey with 2,359 respondents is analysed. Respondents answering the survey on a screen smaller than or equal to an A4 sheet find the visualised wind turbines significantly less visible than respondents answering on a larger screen. These results fuel the debate on using visualisations in internet surveys.
Teolojik Yaklaşımların Arap Gramerine Etkisi
Authors: ARPACIK Mehmet Emin
Published: July 2022

Akide, mezheplerin üzerine bina edildiği temel ilkeler arasındadır. İslami ilimlerde yöntem, kaide ve esasların belirlenmesinde inancın etkisi, izaha gerek duyulmayacak kadar açıktır. İlimde izlenen yöntem gibi benimsenen düşüncenin de etkisi önemlidir. Arap gramerinin (nahiv) sistemleşme sürecinde kelâmî düşüncenin, Kur’an’daki bazı ayetlerin te’viline ve nahvî kural veya ıstılahlara etkisi olduğu söylenebilir. Arap dil ve gramerinin sistemleşmesinde etkisi görülen dilcilerin büyük çoğunluğu Muʽtezilî düşünce özellikle Arap olmayan âlimlerde gözüktüğünden bu noktadan Arap nahvine yaptığı etki veya katkılar göz ardı edilmemesi gerekir. Muʽtezilî düşünceye sahip dilcilerin, bazen benimsenen iʽtikat veya mezhepsel düşünceleri çerçevesinde gramere de müdahale ettikleri görülmektedir. Muʽtezile’nin teolojik kaygılardan veya mezhep düşüncesini savunmak ve haklılığını ispat etmek adına, Ehl-i sünnet ile özellikle ayet yorum veya te’vilinde çeliştiği gözlenmektedir. Muʽtezile’nin dil ve gramerin doğallığı ile bazen çelişebilen akli veya felsefi yorumlarının, Arap gramerinin gelişmesine ve sistemleşmesine bir derece etki ve katkısı ile beraber bu kelâmî düşüncenin dile ve dil yorumuna farklı bir yorum getirdiği söylenebilir. Ehl-i sünnet ile Muʽtezile arasında genelde mezhep ve yaklaşım farklılığından kaynaklı değişik alanlarda yaşanan yorum farklılığının dil ve gramer alanına da taşındığına şahit olmaktayız. Bu çalışmanın i’tikat-dil etkileşimini meselesine farklı açılardan bir derece katkısı olması umulmaktadır.
Memórias do vivido e do sonhado na Regional IV da Associação Brasileira de Ensino de Biologia
Authors: Shuvartz Marilda
Published: July 2022

O presente artigo objetiva rememorar a trajetória de composição e realização dos eventos da Regional 4 da Associação Brasileira de Ensino de Biologia-SBEnbio no período de 2007 a 2019. As memórias dos eventos marcam a caminhada e revelam os resultados das atividades do campo desenvolvidas no ensino, na pesquisa e na extensão nas instituições escolares (Educação Básica), Universidades e outros espaços educativos. Assim, o enlace entre as Universidades e as Escolas coloca os atores destes espaços a realizarem trocas e reflexões que constroem a história e o tempo do Ensino de Biologia, e consequentemente a vida (trajetória) docente.
Entrelaçando histórias, memórias e práticas na constituição da Regional 1 (SP, MS, MT)
Authors: Bizerra Alessandra Fernandes , Silva Rosana Louro Ferreira
Published: July 2022

Este texto tem por objetivo trazer e entrelaçar memórias e práticas da Diretoria Regional 1, em comemoração aos 25 anos da Associação Brasileira de Ensino de Biologia. Trazemos, na primeira parte, um relato descritivo das ações desenvolvidas ao longo dos 22 anos da Regional, pautada em registros empíricos, e na segunda, relatos de memórias e sentidos compartilhados. Finalizamos com a apresentação de desafios presentes ao longo de nossa história, bem como de futuros imaginados. Optamos por trazer as vozes de pessoas que estiveram na gestão da Regional 1, em sua Diretoria Executiva e Conselho Deliberativo e, assim, embora muitos de seus membros tenham sido docentes da Educação Básica ou educadoras/es em outros contextos, é com olhar da universidade pública que construímos este texto.
25 anos de Associação Brasileira de Ensino de Biologia (SBEnBio)
Authors: Pereira Marsílvio Gonçalves
Published: July 2022

Este artigo trata de uma narrativa escrita sobre os 25 anos de Associação Brasileira de Ensino de Biologia (SBEnBio), numa tessitura que articula movimentos e episódios no âmbito nacional e no âmbito da Regional-5/Nordeste desse coletivo, destacando aspectos considerados importantes na formação e profissionalização da pesquisa e da docência na Educação em Ciências e Ensino de Biologia, bem como as origens e avanços da SBEnBio. Os dados para a elaboração deste trabalho foram recolhidos a partir da literatura especializada, em mensagens dadas a solicitações feitas junto a colegas pesquisadores/docentes brasileiros por e-mail e através do WhatsApp, em documentos da SBEnBio (Atas de Assembléias, Anais de eventos, Boletins Informativos, e em fotografias), que se constituem memórias da área de ensino de biologia.
Sobre a experiência de me constituir na SBEnBio e na UFRJ
Authors: Ferreira Marcia Serra
Published: July 2022

O texto aborda as minhas memórias acerca dos vinte e cinco anos da SBEnBio, entidade criada em 1997 durante o VI Encontro ‘Perspectivas do Ensino de Biologia’ na USP. Tais memórias são também atravessadas pelos meus vinte e cinco anos de atuação profissional na UFRJ, formando professores na Licenciatura em Ciências Biológicas. Ao revisitá-las por meio da escrita desse texto, me percebo como sujeito dessa experiência de ser atravessada e transformada, a um só tempo, por ambas as instituições, ao mesmo tempo em que as transformo em minha trajetória profissional. No diálogo com Jorge Larrosa e Reinhart Koselleck, assumo essas memórias como um efeito de todo esse processo que, no presente, articula passado e futuro. Elas devem ser percebidas, portanto, menos pelas ‘verdades’ que anunciam e mais pelos efeitos que irão produzir em quem se propuser a ler esses escritos.
Impact of Climatic Change and Shortage of Water Flow on the Euphrates River Water Salinity between Al-Hindyia and Al-Nasiriya, Southern Iraq
Authors: Muhammed Marwa , Al-Dabbas Moutaz
Published: July 2022

Although the increase in water pollution, the amount of water consumption also increased in population and their activities. The effect of climatic changes are considered as the main effect on Iraqi water resources on its quality and quantity. The goal of the present research is to explain the negative effect of the decreasing of water flow and climate change on the quality of water over the years 2005 to 2010 along the Euphrates river starting from AlHindyia Barrage through Al-Samawa to Al-Nasiriya sites. Historical climatological data of rainfall and temperature for the period 1990 to 2020 and hydrological data of discharge and hydrochimecal analysis for the period 2005 to 2010 were applied in this research. Three gauging stations were chosen on the stretch of the Euphrates River, Al-Hindyia Barrage, Al-Samawa and Al-Nasiriya city. The discharge of Euphrates river is correlated with the Total Dissolved Solids, the major cations (Na+, Ca2+, Mg2+ and K+) and anions (Cl-, SO42-, HCO3-). It was found that the decrease of discharge due to shortage of water resources and climate change led to increase salinity, Total Dissolved Solids and major ions were became higher with time. The concentration of Total Dissolved Solids increased significantly to reach about 846 ppm in Al-Hindyia Barrage and this rate continue to rise in Samawa to about 2545 ppm and Nasiriya 2724 ppm. it was found that the ions Na+, So42- dominated in Al-Hindyia Barrage water while Na+ and Cl- dominated in Samawa and Nasiriya city water.
Subsurface Weathering Zone Determination Using Down-Hole Seismic Surveys, Majnoon Oil Field, Southern Iraq
Authors: Fakher Ahmed J. , Alattabi Abdulhussien N. , Abdullah Murtadha D. , Hussein Mohammed L.
Published: July 2022

Detecting the weathering zone is one of the required data correction steps to process reflection seismic data collected at the Majnoon oil field, south of Iraq. Two subsurface layers represent the weathering zone in this field. Those two layers were inferred by primary seismic waves utilizing the down-hole seismic method. Five wells in the studied area were drilled and named DH-1, DH-2, DH-3, DH-4 and DH-5. The collected seismic data was analyzed to determine the depths, thicknesses and lithology of the subsurface layers. The primary seismic wave velocities were calculated and applied to eliminate two sub-surface layers. The average primary wave velocities and thicknesses of the first layer were 374, 240, 211, 277, 370 m/s, and 2.8, 2, 2, 2, 4.9 m, respectively. In the second layer, the primary waves velocities were 1125, 1284, 1201, 1395 and 1008 m/s, and the thicknesses were 13.2, 11, 13, 11.5, 21.4 m. The first weathered layer represented on the five wells is clay. The second layer has different geometry on different wells, which is represented by a sandy clay layer on DH-1, and muddy clay on DH-2. Then, it is changed to be a silt layer in DH-3, sandy clay in DH-4 and DH-5.
Groundwater Quality Evaluation Using Hydrogeochemical and GIS Techniques in the Southwest Part of Sohag, Egypt
Authors: Othman Fares , Farrag Ahmed , Mohamed Alaa Mostafa , Seleem Elmontser Mahmoud , Salman Salman Abdelraouf
Published: July 2022

Quaternary groundwater is the unique source of freshwater in the desert fringes of the Nile Valley at Sohag, Egypt. This area contains many urban, industrial and agricultural sustainable projects. These activities and the unconfined condition of the Quaternary aquifer have adversely impacted the groundwater quality. This study aims to demonstrate the chemical techniques to understand groundwater conditions and to identify potential hazards of solute dispersion that may exist in the study area, 24 groundwater samples were collected from the study area in August 2019 and analyzed physically and chemically. The results showed that the pH is slightly alkaline and the Total Dissolved Solids of the groundwater was about 1289 mg/l. Most of the studied samples aren’t acceptable for drinking owing to high TDS>1000mg/l and toxic heavy metals, especially As and Pb. The recorded high concentrations of the Total Dissolved Solids and ions can be attributed to sediment salt leaching, agriculture drainage, domestic wastewater, and the applied pesticides, and fertilizers in the study area. Salinity and sodium hazards adversely impact the suitability of most samples for irrigation, but all the studied heavy metals were within the permissible limit for irrigation. Finally, more attention and monitoring of the Quaternary aquifer in the Nile Valley must be considered for the protection of this important aquifer and human health.