bluuebunny/crossref_metadata_2025 huggingface dataset:
Angiotensin Converting Enzyme 1 Expression in the Leukocytes of Adults Aged 64 to 67 Years
Authors: Bueno Valquiria , Destro Pedro Henrique , Teixeira Daniela , Frasca Daniela
Published: December 2022

The renin angiotensin system is composed of several enzymes and substrates on which angiotensin converting enzyme (ACE) 1 and renin act to produce angiotensin II. ACE1 and its substrates control blood pressure, affect cardiovascular and renal function, hematopoiesis, reproduction, and immunity. The increased expression of ACE1 has been observed in human monocytes during congestive heart failure and abdominal aortic aneurysm. Moreover, T lymphocytes from individuals with hypertension presented increased expression of ACE1 after in vitro stimulation with angiotensin II (ATII) with the highest ACE1 expression observed in individuals with hypertension with low-grade inflammation. Our group and others have shown that aging is associated with comorbidities, chronic inflammation, and immunosenescence, but there is a lack of data about ACE1 expression on immune cells during the aging process. Therefore, our aim was to evaluate the levels of ACE1 expression in nonlymphoid cells compared to lymphoid that in cells in association with the immunosenescence profile in adults older than 60 years. Cryopreserved peripheral blood mononuclear cells obtained from blood samples were used. Cells were stained with monoclonal antibodies and evaluated via flow cytometry. We found that ACE1 was expressed in 56.9% of nonlymphocytes and in more than 90% of lymphocytes (all phenotypes). All donors exhibited characteristics of immunosenescence, as evaluated by low frequencies of naïve CD4+ and CD8+ T cells, high frequencies of effector memory re-expressing CD45RA CD8+ T cells, and double-negative memory B cells. These findings, in addition to the increased C-reactive protein levels, are intriguing questions for the study of ACE1, inflammaging, immunosenescence, and perspectives for drug development or repurposing (Reviewed by the Plan P #PeerRef Community).
Reclassified the phenotypes of cancer types and construct a nomogram for predicting bone metastasis risk: A pan-cancer analysis (Preprint)
Authors: Wang Fei , Wang Xin , Mao Min , Zhang Chao , Li Huiyang , Li Xiuchuan , Zhu Pei , Yu Wenqian , Song Fengju , Ma Wenjuan , Chen Qi , Gu Dongqing , Zhang Wei , Hu Jiang
Published: December 2022

BACKGROUND

Numerous of models have been developed to predict the bone metastasis (BM) risk, however, due to the variety of cancer types, it is difficult for clinicians to Use these models efficiently.

OBJECTIVE

We aimed to perform the pan-cancer analysis to create the cancer classification system for BM, and construct the nomogram for predicting the individualized BM risk.

METHODS

Cancer patients diagnosed between 2010-2018 in the Surveillance, Epidemiology, and End Results (SEER) database were included. Unsupervised hierarchical clustering analysis was performed to create the BM prevalence-based cancer classification system (BM-CCS). Multivariable logistic regression was applied to investigate the possible associated factors for BM and construct a nomogram for BM risk prediction. The patients diagnosed between 2017-2018 in SEER were selected for validating the performance of the BM-CCS and the nomogram, respectively.

RESULTS

A total of 50 cancer types with 243,8680 patients were included in the construction model. Unsupervised hierarchical clustering analysis classified the 50 cancer types into three main phenotypes, namely, categories A, B, and C. The pooled BM prevalence in category A (17.7%; 95%CI: 17.5%-17.8%) was significantly higher than that in category B (5.0%; 95%CI: 4.5%-5.6%) and category C (1.2%; 95%CI: 1.1%-1.4%) (p<0.001). Advanced age, male gender, race, poorly differentiated grade, higher T, N stage, and brain, lung, liver metastasis were significantly associated with BM risk, but the results were not consistent across all cancers. Based on these factors and BM-CCS, we constructed a nomogram for predicting the BM risk. The nomogram showed good calibration and discrimination ability and the decision curve analysis also demonstrated the clinical usefulness.

CONCLUSIONS

The classification system and prediction nomogram may guide the cancer management and individualized BM screening, thus allocating the medical resources to cancer patients. Moreover, it may also have important implications for studying the etiology of BM.
Об’єднані заради миру на стоматологічному фронті
Authors: Oshurko A.P. , Sukhliak V.V. , Lysytsia D.L. , Dundiuk-Berezina S.I.
Published: December 2022

У даній роботі висвітлюється роль організації безперервного професійного розвитку в умовах воєнного стану, засадами якого стали збереження й відбудова зруйнованого здоров’я і людського життя в цілому. Намагання добрати необхідний арсенал методів діагностики і належних протоколів реабілітації з першочерговим урахуванням об’єктивної оцінки функціональних розладів, до того ж в обставинах воєнного часу, і відповідним чином коригувати можливості такого лікування стало поштовхом до об’єднання заради миру й добра. Самоорганізація колегіальних, інформаційно-консультативних майданчиків з використанням інструментів доступних соціальних мереж, які згуртували у «відкриті» й «закриті» спільноти людей з різних куточків України і за її межами, для обговорення функціонуючих закладів і наявності потрібних фахівців стала основою прогресуючих механізмів безперервного професійного розвитку й підтвердила свою дієвість у воєнний час щодо надання медичної допомоги для пацієнта і організаційної — для практикуючого лікаря або організатора таких послуг. Також описано результати об’єднуючого телемосту Київ — Рівне з висвітленням професійних, організаційно-правових викликів, що постали перед лікарями-стоматологами, і шляхів їх стрімкої переорієнтації, рішучих професійних дій при прийнятті рішень, поновлення або цілеспрямованого набуття нових знань. Метою даної роботи є виокремлення ролі безперервного професійного розвитку в збереженні повноти і якості стоматологічних послуг в умовах воєнного стану.
Perbandingan Efektivitas Penggunaan Nifedipin Dengan Metildopa Dalam Mengontrol Tekanan Darah Pasien Preeklamsia
Authors: Widayani Sara Septi , Rahmawati Fita , Yasin Nanang Munif
Published: December 2022

Preeklamsia merupakan salah satu gangguan hipertensi selama kehamilan dimana salah satu tanda yang dialami oleh pasien adalah terjadinya peningkatan tekanan darah yang ditunjukkan dengan peningkatan tekanan darah sistolik ≥140 mmHg dan atau tekanan diastolik ≥90 mmHg. Belum banyak bukti yang menunjukkan pilihan terapi paling efektif bagi pasien preeklamsia untuk mengatasi hipertensi selama kehamilan. Tujuan dari penelitian ini adalah membandingkan efektivitas dan profil keamanan terapi antihipertensi yaitu nifedipin dengan metildopa pada pasien preeklamsia. Penelitian ini dilakukan menggunakan metode kohort retrospektif yang dilakukan di RSUD Tidar Magelang selama 3 bulan. Analisis statistik efektivitas diukur berdasarkan penurunan tekanan darah setelah penggunaan antihipertensi menggunakan independent t-test sementara profil keamanan diukur berdasarkan kejadian hipotensi setelah penggunaan antihipertensi. Pengukuran tekanan darah diamati selama 48 jam pasien menjalani rawat inap. Besar sampel penelitian ini adalah 56 dimana 34 pasien mendapat terapi nifedipin dan 22 pasien mendapat terapi metildopa. Hasil deskriptif karakteristik antara kedua kelompok menunjukkan tidak dapat perbedaan antara kelompok nifedipin maupun metildopa (p>0.05). Rata-rata tekanan darah sistolik setelah penggunaan nifedipin adalah 131.15±14.90 dan kelompok metildopa 130.23±12.42(p=0.952). Rata-rata tekanan darah diastolik setelah penggunaan nifedipin adalah 86.59±10.18 dan kelompok metildopa 85.14±7.92(p=0.738). Tidak terdapat perbedaan efektivitas dan profil keamanan pada pasien preeklamsia dengan pemberian nifedipin maupun metildopa.
A Focus Group Discussion on the Beneﬁts of Bio-pigment in Preventing Stunting and Obesity with RPTRA Administrators in South Jakarta
Authors: Biasini Naurissa , Dyanasari Reni , Nurhidayah Fitriyah , Putrianti Pratika Riris , Limantara Leenawaty
Published: December 2022

The problem of stunting in Indonesia has recently been getting worse and has become in the top three positions in Southeast Asia due to the lack of public understanding, one of which is about nutrition. Currently in Jakarta, to reach mothers, RPTRA (Ruang Publik Terpadu Ramah Anak/Child-friendly Integrated Public Space) administrators can assist in providing information about nutrition, especially those that can overcome the problem of stunting more broadly. This activity was carried out to provide more understanding of stunting prevention nutrition for RPTRA administrators. After receiving seminar and workshop materials, a Focus Group Discussion was held for RPTRA administrators regarding the beneﬁts of biopigments in preventing Stunting and Obesity. Each group was given a question related to their knowledge of changes about biopigments beneﬁts in fruits and vegetables. FGD data was analysed by using three methods of coding (open, axial, and selective coding). Eighty per cent of the answers from RPTRA administrators were still limited to sources of nutrition that were commonly used on a daily basis, even though their level of understanding about nutritional sources had increased after the seminars and workshops. The main reason for this was because there was still a view that other sources of nutrition that they had just discovered were considered expensive or diﬃcult to ﬁnd.
Empowerment Program in Pesagi Village Community: Assistance in Compounding Innovative Peel-off Pain Reliever (UNO) Derived from Family Medicinal Plants
Authors: Kurnianta Putu Dian Marani , Yuliawati Agustina Nila , Musthika I Komang Tri , Putri Ni Kadek Ayu Sri Darma , Dianita Ni Luh Putu Asra , Sudiasih Ni Putu , Lestari Ni Made Ayu , Wahyuni Ni Putu Arik Candra , Wiarta I Putu Gede Hendra , Fangidae Powen Ester Jacqlien , Putra I Made Ngurah Arya Kresna Acharya
Published: December 2022

The abundance of family medicinal plants (TOGA) growing in the yards of the house can be utilized for one of the health products called boreh, a traditional medicine used from generation to generation by the Balinese. Boreh can be innovated into a peel-oﬀ preparation form that has some potential to increase public interest in traditional medicine. The contents of TOGA, such as ginger, turmeric, and galangal in the peel-oﬀ boreh preparation, may exhibit beneﬁcial eﬀects as a pain reliever. Therefore, the mentioned product can be used to overcome pain problems that are commonly found in the people of Pesagi Village. The ideas related to compounding certain innovative herbal preparations for overcoming health problems in Pesagi Village were carried out through community empowerment activities. A series of program activities took place during January-April 2022. The purpose of this community empowerment program was to provide training and assistance activities to the people of Pesagi Village in the practice of utilizing TOGA as an innovative boreh peel-oﬀ preparation, namely UNO, with empirical pain reliever properties. Guidance and assistance in compounding practice were based on the results of dosage formulation previously developed by the executive team in the School of Pharmacy Mahaganesha Laboratory. This empowerment program was executed through a learning-by-doing approach, integrated training, participatory practice, and guided mentoring by the executive team with knowledge and skills evaluation (pre-test and post-test, p=0.000, 95%). After the empowerment program, the community has been able to practice how to turn TOGA from the ground into a useful product. The innovative products in this empowerment program may oﬀer some potential beneﬁts to overcome certain health-related problems of the community in Pesagi Village, such as joint pain. The success of this program may encourage the sustainability of the program in the future.
Flash flood (Δ) risk and damage assessment in batu, East Java
Authors: Putra Dekka Dhirgantara , Sofwany Bahrul Fikry , Zulfinanda Hukma , Kamaruddin Iqbal
Published: December 2022

Hydrometeorological disasters are showing an increasing trend in Indonesia. Flash floods are part of a hydrometeorological disaster that has a significant livelihood impact. Flash Flood is triggered by the intensity of extreme rain, several actions of mitigation can be taken by early warning systems, hazard and risk mapping, community preparedness, and climate change adaptation. So, how does future land use have an impact, and how much loss will result from the flash flood disaster in Batu City? The hydrometeorological disaster that occurred in Indonesia was the Batu Flash Flood. The Flash Flood occurred on November 4, 2021. The flash flood has a lot of impact on many locations, including the Bumiaji District and Junrejo District. Based on the disaster history recorded, the flash flood in Batu has only happened once, but the impact was quite big because there are many houses in the midstream of Bulukerto. Based on the losses caused, this can be the basis for efforts to control the spatial pattern of Batu City in the future. The methodology used in this study is risk assessment. While the risk study related to delta (Δ) the study of flash floods risk in spatiotemporal prevention uses the 2030 spatial plan for delta prediction (Δ), which can later predict the consequences of climate change and meteorological disasters from flash floods in Batu. The results of this study are the delta (Δ) of flash flood risk and the damage assessment of the flash flood that occurred in Batu.
Architectural typology of water infrastructure: Case study of green open space and heritage site of perigi pekasem in Bangka Belitung
Authors: Arlianda Reza
Published: December 2022

Indonesia as the top 10 countries in extensive groundwater extraction, has fallen behind in providing basic water services infrastructure. While the water utility in Indonesia only provides 35.15% coverage nationally. As case, Bangka Belitung as the lowest province in water management provision with only 17.26% coverage faces tremendous sustainable issues because of its massive exploitation of water usage for domestic, industrial, and especially tin mining activities. Indeed, in spite of fact that water infrastructure is always an essential part of the history of the built environment such as the Roman aqueduct, India’s Stepwell, and Nasqa Puquio. In Indonesia has shown that the number of architectural studies focused on improving the water services is small. In response to Sustainable Development Goals number 6 on clean water and sanitation, this study aims to contribute and mainstream the discussion of green infrastructure in the architecture discourse by analyzing and identifying its typology and design elements using the heritage-built environment of Bangka Belitung’s perigi as the case study. The result of identified design elements and typology on the cultural landscape can further be used to enrich the architecture discussion and design vocabulary on Indonesian cities’ urban fabric and contribute to the expected achievement progress on sustainable development goals.
НА РЫНОК ВЫШЕЛ НОВЫЙ ОТЕЧЕСТВЕННЫЙ ВЕНДОР ТЕЛЕКОММУНИКАЦИОННОГО СЕТЕВОГО ОБОРУДОВАНИЯ
Authors: Попов С.
Published: December 2022

23 ноября компания N3COM, российский производитель телекоммуникационного сетевого оборудования операторского класса, провел в Москве первый ознакомительный семинар для операторов связи и корпоративных заказчиков. Потенциальным заказчикам были представлены линейки оборудования компании DWDM/OTN, IP/MPLS, MPLS-TP, GPON/XGS-PON, коммутаторы Ethernet, а также сетевая система управления.
ВОПРОСЫ КОНСТРУИРОВАНИЯ ОПТИЧЕСКИХ КАБЕЛЕЙ ДЛЯ ПРИМЕНЕНИЯ В ТЕРАБИТНЫХ СИСТЕМАХ ПЕРЕДАЧИ
Authors: Боев М. , Ким Э. , Микилев А.
Published: December 2022

Рассмотрены вопросы конструирования, промышленного производства, методик и задач исследования оптических кабелей с оптическим волокном со сверхнизким затуханием и большой эффективной площадью.
ИНФОКОММУНИКАТИВНАЯ КОМПЕТЕНЦИЯ – ВАЖНОЕ ПРОФЕССИОНАЛЬНОЕ КАЧЕСТВО КВАЛИФИЦИРОВАННОГОСПЕЦИАЛИСТА
Authors: Романенко О. , Студянникова М.
Published: December 2022

В статье рассмотрен феномен "информационно-коммуникативная компетенция" как одна из важных составляющих профессиональной социальной компетентности современного квалифицированного специалиста. В работе дается характеристика действующих профессиональных навыков и знаний, подтверждающих профессиональную квалификацию специалиста в современном обществе; раскрываются такие понятия, как профессиональная, методическая, социальная, коммуникативная, социокультурная, информационная компетенции; выявляется роль владения информационно-коммуникативной компетенцией в профессиональном становлении личности. Предпринята попытка проанализировать коммуникативные модели и техники, способствующие гармоничному взаимоотношению, успешному сотрудничеству, лидерству. Проведен анализ техник и моделей, положительно влияющих на становление информационно-коммуникативной компетенции. Предложены рекомендации для оптимизации процесса формирования вышеназванных компетенций будущих специалистов.
Editorial
Authors: Paíno Perdomo Omar
Published: December 2022

No necesita de un resumen.
Experimental Study on Sisal Fiber Reinforced Concrete with Addition of Fly Ash
Authors: Yeswanth M. , Jenitaa M.
Published: December 2022

Abstract: Concrete is strong in compression but weak in tension. So we will provide the reinforcement to the concrete. Fiber Reinforced Concrete FRC can be used for a variety, of applications. Sisal is a natural fiber that is renewable, inexpensive, and readily accessible. SSF is a potential reinforcement for use in concrete because of its cheap cost, low density, high specific strength and modulus, negligible health risk, easy accessibility in certain states, and renewability. The manufacturing process of cement .emits considerable amount of carbon dioxide (CO2) . Therefore there is an urgent need to reduce the usage of cement. Fly ash is produced from the combustion of coal in electric utility or industrial boilers. The concrete in which the cement is replaced up to 40%. The study focuses on the compressive strength, split tensile strength, performance of the blended concrete containing Na2CO3 is treated with sisal fiber for 5 days on the strength parameters normal concrete had been carried out by varying percentages of 4%, 6%, 8%, 10% for M30 grade of concrete design by using IS10262-2009. Concrete cubes and cylinder are tested at the age of 7, 14, and 28 days of curing
Quantify the Physical Properties of Concrete by Partial Replacement of River Sand by M- Sand Using Fly Ash as Mineral Admixture
Authors: Jennifer Salonica , . Basavalingappa , H. M Veereshaiah , N. M GurupadaSwamy
Published: December 2022

Abstract: Sand and cement, which go into making concrete, is in great demand because it is a crucial building material. Due to this demand, environmental degradation is rising during the production of cement and river basins are running out of sand. Concrete is being updated with suitable substitutes without sacrificing its durability and strength. Fly ash and M sand are used in this study as alternatives to cement and fine aggregates, respectively. Fly ash is by product of combustion process; hence utilizing this product in concrete can be advantageous to both the environment and cost considerations. Whereas M sand is obtained by crushing aggregates into desirable sizes which can benefit workability of concrete .The percentage of these alternatives for which partial replacement results in higher test values is indicated in this study. Super plasticizer was used in testing on newly laid concrete. M 45 grade concrete mix design as per IS 10262:2019 is calculated. Testing was done on M45 grade fresh concrete for workability: slump cone test, compaction factor test, vee bee consist-meter test, as well as hardened concrete for compression strength, tensile strength, and flexural strength. The tests were conducted for variable percentages of fly ash and M sand by weight of cement and natural sand replacement. In this study natural sand is replaced with M sand in 0, 10, 20, 30, 40 & 50% for every 0%, 10% & 15% replacement of fly ash with cement. Satisfying results were found for 10% fly ash and 40% M sand mix for both workability tests and strength tests conducted in the specimen.
Active and Reactive Power Control in Transmission Line with PSO Optimized PI controlled Five Level UPFC
Authors: Jayachandra R , Das Dr. G. Tulasi Ram
Published: December 2022

Abstract: In this paper, particle swarm optimization (PSO) optimized PI controlled five level UPFC is proposed for a double circuit transmission line. To enhance UPFC performance, a different approach is considered here. It uses simplified power system models to derive the decoupled power controllers, but detailed modeling of the UPFC power converters improves their ride-through capability. This paper introduces decoupled linear UPFC power controllers to obtain the reference ac voltages and currents for the two back-to-back-connected three-phase five-level NPC converters that enforce active and reactive power control in the transmission line. This paper proposes three main contributions to increase the dc-link voltage steadiness of multilevel UPFCs under line faults: 1) decoupled active and reactive linear power controllers; 2) real-time PWM generation; and 3) balancing of dc capacitor voltages. The MATLAB/SIMULINK model for the proposed circuit with PSO-optimized PI controlled five level UPFC is shown here with the results.
Review on Forbidden Car Detection System Based on Image Processing
Authors: Sharma Nidhi , Tyagi Pulkit , Raj Rishabh , Pal Saket , Jain Vivek
Published: December 2022

Abstract: This study aims to detect vehicles that are parked at no parking area so that it can be used as forbidden parking management and find out the illegally parked vehicle that are parked on roadside. In this study, we are using Image Processing techniques and Machine Learning.
Configuration of user interface for evaluation of runoff in Orontes basin using artificial intelligence
Authors: Slieman Alaa , Kozlov Dmitry V.
Published: December 2022

Introduction. Surfacе runoff is of great importance for water resources formation processes in a river basin. The purpose of this study is to develop a user interface for a numerical solution to the problem of evaluating the runoff in the El-Asi (Orontes) River basin in Syria using artificial intelligence models.

Materials and methods. The method of artificial neural networks was used to design the user interface. The task was solved in three stages: training, verification and testing. Several types of model algorithms were tested. Efficiency values were compared for different models using correlation coefficients and the mean root square error.

Results. The authors have found that feed-forward artificial neural networks and back propagation artificial neural networks show the best result if used to make hydrological forecasts and simulate nonlinear functions; that’s why they were applied to the user interface. The developed software tool saves the user’s time and effort, because it generates a very large group of models pursuant to various parameters and functions. It selects the best model according to the effectiveness criteria (such as correlation coefficient R and mean root square error MRSE), and allows the performance of other operations, such as the graphical representation of output data, the structure of the model used or the onset of evaluation of runoff values. The software is developed in the operational environment of MATLAB.

Conclusions. The software tool is simple and user friendly; it complies with the user-focused methodology, which is easily implemented from the moment the software, is launched through the sequence of activated interface commands. It is recommended to expand the use of artificial intelligence models for forecasting and evaluating elements of the hydrological cycle, especially in absence of source data.
Practical tools of an integrated construction cost management system
Authors: Moshkalev Dmitrii S.
Published: December 2022

Introduction. The problem of effective construction cost management can arise at any stage of a construction project, and it becomes particularly relevant amid economic instability. Solving problems of accurate assessment and control of construction costs is vital for all participants in the investment and construction process. The construction cost management process encompasses the following interrelated sub-processes: identification of reliable construction costs at stages of preliminary and working design; construction cost control at further stages, including the drafting of working design documentation and facility construction. The subject of research is a set of practical tools that solve construction cost management problems throughout the lifecycle of a construction facility.

Materials and methods. Data on cost analysis processes, methods and tools were collected, systematized and analyzed in the course of the study. A systematic approach, analysis and synthesis methods, expert and comparative assessment methods were applied.

Results. The main principles, underlying the author’s approach, as well as a set of practical tools designed to manage the cost of construction of a capital construction facility were proposed in reliance on the analysis, conducted by the author.

Conclusions. The author proposes construction cost management methods and practical tools that can be applied in the course of implementation of investment and construction projects that have different degrees of complexity.

KEYWORDS: planning, management, pricing in construction, construction cost, design documentation, working design, construction
Optimization of engineering solutions used to develop the underground spaces of existing buildings
Authors: Zigangirova Leysan I. , Galiev Ilyas Kh. , Ibragimov Ruslan A. , Shakirzyanov Farid R.
Published: December 2022

Introduction. The article deals with the optimization of engineering solutions applied in the course of arrangement of additional underground spaces under existing buildings. The decreasing number of unoccupied spaces in the central areas of developing cities and the fact that the expansion of spaces under existing buildings allows the city to effectively and organically develop its territories explain the relevance of this research.

Materials and methods. The authors apply the central composite Box design, that is used to construct second order polynomials to make a plan of a two-factor composite (rotatable) experiment with a quadratic model. To solve this problem, the following software programmes were used: Gradient 3.1; Mathematica. The object of numerical calculations is a frameless 3-storey building. The structures, used to calculate the labour intensity of the work performed, included piles, ground beams, and foundation grillages. The weight of metal structures and the labour intensity were the parameters to be studied.

Results. A mathematical model was developed and dependence functions of the studied parameters, affecting the reinforcement of an existing building during the redevelopment of its underground space, were obtained. Optimal values of (1) weight of metal structures and (2) the labour intensity, reducing the total cost of the proposed technology, were identified. The Mathe­matica software package was applied to identify the optimal beam spacing that varied from 1.2 to 1.5 m.

Conclusions. The function, obtained by the authors, describes the curve showing dependence between the following two parameters: the weight of metal structures, used to reinforce the building, and the labour intensity of installation work. Optimal values of the studied parameters, ensuring minimal weight and labour intensity, are identified to reduce the total weight of metal structures, used to reinforce the existing building and reduce the overall cost of the proposed technology.
UMA ANÁLISE SOBRE O DESENVOLVIMENTO SOCIAL NOS MUNICÍPIOS DO AGRESTE MERIDIONAL DE PERNAMBUCO DE 2000 A 2018: EFEITOS SOCIAIS DA IMPLANTAÇÃO DA UFAPE
Authors: Almeida Costa Gewehr Flávia , Gois de Oliveira Marcos Roberto , Gatto Maria Fernanda
Published: December 2022

O presente trabalho teve como objetivo principal analisar a evolução dos indicadores sociais dos municípios do Agreste Meridional, no intuito de identificar a influência da implantação da Universidade Federal do Agreste de Pernambuco na região. Especialmente buscou-se observar os efeitos sociais da implantação da UFAPE, para o município de Garanhuns, onde está sediada, bem como para os demais municípios do Agreste Meridional, buscando avaliar a progressão desses efeitos para o desenvolvimento social da região como um todo. Para isso, além do Índice de Desenvolvimento Humano - IDH, também foram analisados os indicadores de Educação dos municípios do Agreste Meridional como os índices Firjam de Desenvolvimento Municipal – IFDM-Educação, que avalia o grau de desenvolvimento da educação dos municípios brasileiros, e o percentual de docentes com formação superior, no intuito de observar a melhoria do capital humano atuante nas escolas da região. Assim, apoiando-se em literatura pertinente e nos indicadores expostos, foi possível apontar para as influências da UFAPE nas transformações da dinâmica social dos municípios do Agreste Meridional.
QUAL O IMPACTO DAS INOVAÇÕES SOBRE O CRESCIMENTO ECONÔMICO? UMA ANÁLISE COM A METODOLOGIA PVAR PARA OS PAÍSES DA OCDE NO PERÍODO DE 1985 A 2017
Authors: Silva Jose Alderir , Silva Igor Ezio Maciel
Published: December 2022

Este artigo tem por objetivo analisar, sob a perspectiva da Teoria do Crescimento Endógeno, a relação positiva entre inovação e crescimento econômico. Para tanto, utilizou-se a abordagem Panel Data Vector Autoregressive (PVAR) com o objetivo de estimar o impacto de algumas variáveis relacionadas com a inovação sobre o crescimento econômico dos países da OCDE no período de 1985 a 2017. Os resultados mostram que choques positivos nas variáveis grau de abertura comercial e gastos em Pesquisa e Desenvolvimento (P&D) têm um efeito positivo sobre o PIB per capita dos países. Considerando uma amostra apenas com países com renda abaixo da média da OCDE, foram encontrados resultados similares. Já para uma amostra considerando apenas os países com renda acima da média, choques positivos nas variáveis grau de abertura e Investimento Direto Estrangeiro têm efeitos líquidos positivos no PIB per capita. Os resultados sugerem, ainda, que os países mais ricos tendem a se beneficiar mais dos gastos em P&D, uma vez que seu efeito sobre o PIB per capita é mais prolongado em relação aos demais.
Novos sentidos sobre o Brasil Grande Potência
Authors: Mallmann Vinícius Henrique , Silva André Luiz Reis da
Published: December 2022

Objetiva-se analisar, por meio do discurso, a construção da imagem – interna e externa – do Projeto “Brasil Grande Potência” e como essa imagem foi transmitida e utilizada pelos meios políticos e diplomáticos para projetar o país como uma Potência. Foram analisados, previamente, os 102 discursos de Médici, bem como os 4 discursos proferidos pelo chanceler Mário Gibson Barbosa para a ONU durante o seu mandato. Dos discursos de Médici, foram selecionados os que melhor representavam as ações do governo e a sua interlocução com o Projeto “Brasil Grande Potência” e nos quais foi identificada a palavra-chave “desenvolvimento”. Tais discursos foram contrastados com a bibliografia existente (artigos, livros, documentos oficiais e da imprensa). Após a seleção, foi aplicada a teoria de Análise de Discurso a fim de esboçar como o processo discursivo desse projeto foi realizado. Chega-se à conclusão de que o Projeto “Brasil Grande Potência” encontrou obstáculos na esfera internacional (materializado na crítica ao "congelamento de poder") na busca pelo desenvolvimento, o que gerou uma dicotomia discursiva da projeção da imagem do país: internamente, era tratado como uma Grande Potência; externamente, como um país intermediário ou uma Potência Média.
Panorama da mineração na Paraíba: a industrialização como promessa de desenvolvimento
Authors: Seidel Monique Alessandra , Lima Gustavo Ferreira Costa , Silva Edevaldo
Published: December 2022

Este estudo observou e discutiu a atividade minerária no Estado da Paraíba a partir dos dados Compensação Financeira pela Exploração de Recursos Minerais (CFEM). Foram discutidas as características dessa atividade, identificando os minérios mais explorados e regiões de intensa mineração. Além disso, discute esses dados observando os possíveis conflitos ambientais envolvidos no contexto. Para tanto, foi realizado um estudo histórico decenal (2012-2021) e trianual (2019-2021) da extração mineral no estado para analisar avanços e tendências geográficas dessa atividade. São mais de 30 minerais extraídos em 29 municípios. Cinco deles concentram 80% do CFEM arrecadado, principalmente, a partir da extração de titânio (ilmenita), zircônio e calcário e água mineral. Preocupações socioambientais envovem algumas dessas atividades.
Propriedade e apropriação no bairro do Pinheirinho – Alfenas/MG
Authors: Branquinho Evânio dos Santos , Amaral Danilo Lenine Ferreira do
Published: December 2022

A pesquisa propõe investigar a propriedade e a apropriação relacionadas à produção do espaço no bairro do Pinheirinho – Alfenas/MG, identificando nesse processo as formas materiais e imateriais. O estudo sobre a produção do espaço pressupõe a mobilização de tríades, fundamentadas por categorias e conceitos. As tríades possibilitam interpretar as relações de produção e reprodução do bairro, marcado pela forte presença do setor imobiliário e do Estado, que atuam para a valorização do solo urbano. Outro elemento que se revelou foi o uso ao nível da sobrevivência dos moradores. Os procedimentos metodológicos adotados baseiam-se em revisão bibliográfica; entrevistas semiestruturadas com os moradores do bairro e arredores, vereadores, prefeito, funcionários públicos e comerciantes; levantamento de dados estatísticos, cartográficos e fotográficos.
O terroir como categoria geográfica: origem e abordagens conceituais.
Authors: Oliveira Edvaldo , Lisboa Gerson dos Santos , Silva Vinícius de Amorim
Published: December 2022

O conceito de terroir, traduzido como “gut da terre”, tem sido debatido nas esferas da teoria da produção agrícola tradicional versus globalização da agricultura. Sem uma tradução clara, sua origem é antiga, mas consolidada na França, especificamente na viticultura e traz muitas questões quando aplicado a outras culturas. O artigo busca nas refrências estrangeiras o conceito e as formas de manutenção do terroir denominado natural em contraposição do que convencionou chamar de terroir tecnológico, baseadao na grande produção. Busca relacionar o terroir com o território com a categoria geográfica. Defende a pequena propriedade como exemplo para o terroir natural a partir das condicionantes físicas como solo e clima.
Corporate governance parameters and their impact on enterprise performance
Authors: Choudhury Arunabh , Sultana Mafruza , Gupta Pooja
Published: December 2022

Corporate governance incorporates the framework of ethical and legislative decision-making approaches within the management, which empowers the relationship between the firm and its stakeholders. The affiliation between economic enactment and management and governance of the enterprises has helped attract external stakeholders to the business. This research aims to assay the effect of corporate governance parameters on the accomplishment of the sampled enterprises. The study has used a sample of S&P CNX Nifty 50 Index enterprises, excluding banking and financial services enterprises, during the period of FY2012–2013 to FY2018–2019. Panel linear model regression with pooled ordinary least squares (OLS) test has been used to analyze the data. Results show that there is a link between and impact of board parameters such as board size and audit committee (AC) independence on the market and financial outcomes of the enterprise’s proxies by return on net worth (RONW), return on capital employed (ROCE), return on assets (ROA), and Tobin’s Q.
Gas chromatographic separation of the FAME prepared from dairy products, PHO, and refined vegetable oils applying a negative temperature gradient.
Authors: Delmonte Pierluigi
Published: December 2022

To date no single gas chromatographic method can simultaneously measure
all fatty acids (FA), including trans FA (TFA), that are contained in
dairy products, partially hydrogenated oils (PHO), and refined vegetable
oils. Using 100% poly(biscyanopropyl siloxane) capillary columns,
ruminant and dairy fats are preferentially analyzed by applying
temperature programs that separate short chain FA, but not trans-18:3
from 20:1. Refined vegetable oils and PHO are preferentially analyzed by
applying isothermal elutions that provide quantification of all 18
carbon TFA including trans-18:3 FA, but not of all short chain FA. In
this short communication, we propose a temperature program method
capable of simultaneously measuring short chain FA and all 18 carbon TFA
including trans-18:3 by applying a negative temperature gradient after
the elution of trans-18:1. A simplified version of the method is also
described for equipment not able to perform negative temperature
gradients.
Radial equivalence and applications to the qualitative theory for a class of non-homogeneous reaction-diffusion equations
Authors: Iagar Razvan Gabriel , Sánchez Ariel
Published: December 2022

Some transformations acting on radially symmetric solutions to the
following class of non-homogeneous reaction-diffusion equations
| x | σ 1 ∂ t u = ∆ u m + | x | σ 2
u p , ( x , t ) ∈ R N × ( 0 , ∞ ) , which has been proposed in a number
of previous mathematical works as well as in several physical models,
are introduced. We consider here m≥1, p≥1, N≥1 and
σ 1 , σ 2 real exponents. We apply these transformations in connection
to previous results on the one hand to deduce general qualitative
properties of radially symmetric solutions and on the other hand to
construct self-similar solutions which are expected to be patterns for
the dynamics of the equations, strongly improving the existing theory.
We also introduce mappings between solutions which work in the
semilinear case m=1.
Addressing uncertainty when projecting marine species distributions under climate change
Authors: Davies Sarah , Thompson Patrick , Gomez Catalina , Nephin Jessica , Knudby Anders , Park Ashley , Friesen Sarah , Pollock Laura , Rubidge Emily , Anderson Sean , Iacarella Josephine , Lyons Devin , MacDonald A. Andrew , McMillan Andrew , Ward Eric , Holdsworth Amber , Swart Neil , Price Jeff , Hunter Karen
Published: December 2022

Species distribution models (SDMs) have been widely used to project
terrestrial species’ responses to climate change and are increasingly
being used for similar objectives in the marine realm. These projections
are critically needed to develop strategies for resource management and
the conservation of marine ecosystems. SDMs are a powerful and necessary
tool; however, they are subject to many sources of uncertainty. To
ensure that SDM projections are informative for management and
conservation decisions, sources of uncertainty must be considered and
properly addressed. Here we provide ten overarching guidelines that will
aid researchers to identify, minimize, and account for uncertainty
through the entire model development process, from the formation of a
study question to the presentation of results. These guidelines were
developed at an international workshop attended by over 50 researchers
and practitioners. Although our guidelines are broadly applicable across
biological realms, we provide particular focus to the challenges and
uncertainties associated with projecting the impacts of climate change
on marine species and ecosystems.
Variance Components of Sex Determination in the copepod Tigriopus californicus estimated from a pedigree analysis.
Authors: Richardson Jean , Alexander Heather , Anholt Bradley
Published: December 2022

Strong theory exists regarding population sex ratio evolution that
predicts equal sex ratio (when parental investment is equal). In most
animals, sex chromosomes determine the sex of offspring, and this fixed
genotype for sex has made theory difficult to test since genotypic
variance for the trait (sex) is lacking. It has long been argued that
the genotype has become fixed in most animals due to the strong
selection for equal sex ratios. The marine copepod Tigriopus
californicus has no sex chromosomes, multiple genes affecting female
brood sex ratio and a brood sex ratio that responds to selection. The
species thus provides an opportune system in which to test established
sex ratio theory. In this paper we further our exploration on the
possibility that T. californicus has polygenic sex determination
using an incomplete diallel crossing design and the “animal model” for
analysis of the variance components of sex determination in the species.
Our data confirm the presence of extra-binomial variance for sex,
further confirming that sex is not determined through simple Mendelian
trait inheritance. In addition, our crosses and backcrosses of isofemale
lines selected for biased brood sex ratios show intermediate phenotypic
means, as expected if sex is a threshold trait determined by an
underlying “liability” trait controlled by many genes of small
effects. Finally, we estimate heritability of an individual to be male
or female on the observed binary scale as 0.09 (95% CI: 0.034-0.14).
This work furthers our accumulating evidence for polygenic sex
determination in T. californicus.
Conformable mathematical modeling of the COVID-19 transmission dynamics: A more general study
Authors: Thabet Hayman , Kendre Subhash
Published: December 2022

Many challenges are still faced in bridging the gap between Mathematical
modeling and biological sciences. Measuring population immunity to
assess the epidemiology of health and disease is a challenging task and
is currently an active area of research. However, to meet these
challenges, mathematical modeling is an effective technique in shaping
the population dynamics that can help disease control. In this paper, we
introduce a Susceptible-Infected-Recovered (SIR) model and a
Susceptible-Infected-Recovered-Exposed-Deceased (SEIRD) model based on
conformable space-time PDEs for the Coronavirus Disease 2019 (COVID-19)
pandemic. As efficient analytical tools, we present new modifications
based on the fractional exponential rational function method (ERFM) and
an analytical technique based on the Adomian decomposition method for
obtaining the solutions for the proposed models. These analytical
approaches are more efficious for obtaining analytical solutions for
nonlinear systems of partial differential equations (PDEs) with
conformable derivatives. The interesting result of this paper is that it
yields new exact and approximate solutions to the proposed COVID-19
pandemic models with conformable space-time partial derivatives
Tracheal resection in locally recurrent differentiated thyroid cancer; a case report.
Authors: Singh Vijay , Singh Akash , Sircar Sumantra , Choudhary Rahul , Ranjan Priyadarshi , Jha Arun
Published: December 2022

Locally recurrent papillary carcinoma of thyroid is a treatable disease.
For endotracheal invasion, tracheal resection and anastomosis is a
viable option in certain cases which gives significant result. Case
presentation: A 46 year female patient with a history of total
thyroidectomy + bilateral neck dissection for carcinoma thyroid two
years back presented with recurrent thyroid mass in neck with
endotracheal invasion. This was successfully treated with segmental
tracheal resection with end to end anastomosis after 4 cm defect. Post
– operative course was uneventful. Conclusion: Endotracheal invasion of
recurrent carcinoma thyroid is not a contraindication for surgery. Full
circumferential resection and end to end anstomosis is preferred to
shaving trachea. It can be safely anastomosed upto 5 cm defect length.
Apart from giving immediate relief of intratracheal bleeding and
obstructive airways, it gives long term disease free survival.
Causes for decadal trends in Surface Solar Radiation in the Alpine region
Authors: Correa Lucas Ferreira , Folini Doris , Chtirkova Boriana , Wild Martin
Published: December 2022

Extending across seven countries, the Alps represent an important
element for climate and atmospheric circulation in Central Europe. Its
complex topography affects processes on different scales within the
atmospheric system. This is of major relevance for the decadal trends in
Surface Solar Radiation (SSR), also known as Global Dimming and
Brightening (GDB). In this study we analysed data from 14 stations in
and around the Swiss and Austrian Alps, over a period ranging from the
1960s up to the 2010s, with the aim of characterizing the
spatio-temporal variations of the GDB and understanding the causes for
such trends in this region. Our results showed a different behavior in
the SSR decadal trends in the western part of the Alps in comparison to
the eastern part. We also identified a remarkable difference between the
causes of such trends in the stations at low altitudes in comparison to
the station at higher altitudes. The SSR trends under cloudy conditions
revealed strong evidence for a control of the decadal trends by cloud
optical depth at high elevation sites, in contrast with a strong
clear-sky forcing at low elevations. Results from previous literature
and available data suggest that such phenomena could be associated with
the indirect and direct aerosol effect, respectively, due to differing
pollution levels.
Responses of phytoplankton communities to internal waves in oligotrophic oceans
Authors: Ma Lingqi , Bai Xiaolin , Laws Edward Allen , Xiao Wupeng , Guo Cui , Liu Xin , Chiang Kuo-Ping , Gao Kunshan , Huang Bangqin
Published: December 2022

Nutrients associated with internal waves are known to perturb
phytoplankton communities in oligotrophic oceans, but details of the
relevant processes and mechanisms are unclear. Here we report insights
about the impacts of internal waves on the phytoplankton community based
on 154-hour time-series of observations in an oligotrophic basin of the
South China Sea. We found that the temporal variations of phytoplankton
communities in the upper, middle, and lower layers of the euphotic zone
differ. We demonstrated that these changes probably resulted from the
perturbation caused by internal waves. These results suggest that the
structure of the phytoplankton community in oligotrophic oceans is best
described by a three-layer system at steady state and that the
perturbation caused by internal waves helps to reveal this structure. We
believe that the paradigm of this three-layer structure will provide a
new theoretical framework for the study of phytoplankton-based
biogeochemical processes in oligotrophic oceans.