bluuebunny/crossref_metadata_2025 huggingface dataset:
JENIS-JENIS TANAMAN DI LAHAN GARAPAN PETANI KPPH WANA MAKMUR DALAM TAHURA WAN ABDUL RACHMAN
Authors: Prasetyo Agung Dwi , Indriyanto Indriyanto , Riniarti Melya
Published: August 2019

The increasing needs and the nearness residential distance from the forest were several factors that caused society to do the utilization of the forest land. Sungai Langka village was a village directly adjacent to the Wan Abdul Rachman great forest park area, where most societies were farmers who manage the land inside the Wan Abdul Rachman great forest park area. The objective of this research i.e.: 1) To find out the species of plants cultivated by farmers on the land-based on habitus, plant groups, and commodities produced; 2) to count the density of each plant group; 3) to find out the most plants as a source of farmers incomes.  This research was conducted with a vegetation survey using the terraced line method. The number of sample plots used was 69 pieces measuring 20m x 20m, 10m x 10m, 5m x 5m, and 2m x 2m. The results of the study showed that there were  35 plants species on farmers cultivated land which is dominated by plants of the forest group MPTS with a density of 3,637.66 individuals/ha, forest wood plant 797,83 individuals/ha, agricultural MPTS 2,294.2 individuals/ha, and agricultural crops 1,533.34 individuals / ha.  Therefore, could be concluded that most of the plants on arable land were fruit-producing plants which were partially included in the MPTS forest group plants, and farmers rely on crops such as cocoa, banana, durian, clove, nutmeg, rubber, petai, pepper and vanilla as the source of income and fulfill their needs.
SKRINING FITOKIMIA EKSTRAK METANOL, KLOROFORM DAN N-HEKSAN DAUN FLAMBOYAN
Authors: Tjitda Putra Jiwamurwa Pama , Nitbani Febri O.
Published: August 2019

Telah dilakukan penelitian tentang skrining fitokimia pada ekstrak daun flamboyan (Delonix regia. Raf). Penelitian ini bertujuan untuk mengetahui senyawa metabolit sekunder pada ekstrak daun flamboyan meliputi flavonoid, alkaloid, saponin, tanin dan fenolik. Penelitian diawali dengan pembuatan ekstrak metanol, kloroform dan n-heksan daun flamboyan menggunakan metode maserasi. Masing-masing ekstrak selanjutnya dilakukan skrining fitokimia. Hasil skrining fitokimia menunjukkan semua ekstrak daun flamboyan mengandung flavonoid, alkaloid, tanin dan fenolik. Kandungan saponin tidak terdapat pada ekstrak kloroform dan n-heksan sedangkan hasil positif saponin terdapat pada ekstrak methanol daun flamboyan. Kata Kunci: Daun Flamboyan (delonix regia. Raf), Skrining Fitokimia, Metabolit Sekunder
Certain Results on (p,q)-Hermite Based Apostol Type Frobenius-Euler Polynomials
Authors: Khan Waseem , Khan Idrees Ahmad , Duran Ugur , Acikgoz Mehmet
Published: August 2019

In the present paper, the (p,q)-Hermite based Apostol type Frobenius-Euler polynomials and numbers are firstly considered and then diverse basic identities and properties for the mentioned polynomials and numbers, including addition theorems, difference equations, integral representations, derivative properties, recurrence relations. Moreover, we provide summation formulas and relations associated with the Stirling numbers of the second kind.
An Examination on the Knowledge Level of Breast Self-Examination of the Patients Who Apply to a University Hospital
Authors: Toraman Aynur , Oksay Aygen , Taş Fatma
Published: August 2019

Objective: The main aim of
this study is to examine the knowledge level of
women on breast cancer who admitted to the outpatient clinics of Obstetrics and
Gynecology and General Surgery of University Hospital.Materials and Methods: The universe is
formed by the patients that have applied to the clinics of Obstetrics and
Gynecology and General Surgery of the University Hospital within the dates of
June-July 2016. Within this study data was collected by the Champion’s Health
Belief Model Scales (CHBMS) and a total of 351 participants were reached. Results: The 43.6% of the sample
consists of women of 20-29 ages, 71% of them are married and 27.4% of them have
either an undergraduate or a post graduate degree. The perceived benefits
concept has the most mean out of the 6 concepts in CHBMS. The study also showed
that although 79.2% of the participants didn’t have a breast problem; 27.6 % of
them said that they would do breast self-examine 3-4 times in a year.

Conclusion: As a
result we can say that the participants are aware of the importance of breast
self-examination and that they have learned it from health professionals.
Koenzim Q10 : Biyolojik Aktivitesi ve Sağlık Üzerine Etkisine Güncel Bakış
Authors: TOPRAK Kadriye , AYAZ Aylin
Published: August 2019

Koenzim Q10, endojen olarak sentezlenen ve yağda
çözünen bir benzokinon bileşiğidir. Mitokondrial enerji üretimindeki görevi ve antioksidan özelliği koenzim Q10’nin
bugüne kadar en iyi bilinen fonksiyonlarıdır.
Ayrıca koenzim Q10’nin
hücre sinyalizasyonunda ve gen ekspresyonunda görev aldığı, hücresel redoks
reaksiyonlarında, hücre büyümesi ve
apoptozisin kontrolünde de önemli görevleri olduğu belirtilmiştir.
Bu biyolojik aktiviteleri nedeniyle
kalp sağlığı, yüksek tansiyon,
diyabet ve kanser gibi hastalıkların tedavisinde yardımcı olarak kullanılmakta,
ayrıca alzheimer ve parkinson gibi bazı nörodejeneratif hastalıkların
tedavisinde de etkili olduğu bildirilmiştir. Özellikle yaşlanma ile beraber
dokularda azalan koenzim Q10 miktarının diyetle birlikte alımının
yetersiz olduğu bildirilmiştir. Hastalıkların
patolojisinde vitaminin rolü ve önlenmesine yönelik mekanizmaların anlaşılması
için deneysel ve gözlemsel çalışmalara ihtiyaç duyulmaktadır. Bu derleme yazıda koenzim Q10’nin
sağlık üzerine etkilerinin güncel çalışmalara göre değerlendirilmesi
amaçlanmıştır.
Hubungan Financial Deepening dan Pertumbuhan Ekonomi: Studi Empiris di Indonesia
Authors: Panjawa Jihad Lukis , Widianingrum Ira Fitriani
Published: August 2019

Financial deepening has been identified as one of the strategies which can accelerate the rate of development. Deepening the financial sector is one important step in the effort to develop the country's financial markets especially developing countries one of which Indonesia. In this research will identify is the relationship between finacial deepening, the exchange rate of rupiah, interest rates and economic growth in Indonesia year of 1985-2015. The approach used in this study is the causality granger. The results in this study was the performance of the financial sector is still shallow. Financial deepening and economic growth have a one-way relationship, namely economic growth affects the financial deepening. Evidence that the introduction of Demand-Following Hypothesis in Indonesia. The exchange rate of the rupiah and financial deepening do not influence each other, as well as economic growth and the exchange rate of the rupiah not influence each other.
Glycan from Macro Fungus
Authors: Pillai Thulasi G
Published: August 2019

Glycan are fascinating biomolecules found abundantly in Nature. This precious compound has very high potential in various domains useful to mankind. Some Glycans are known to have anti tumor property. These biomolecules are less explored for their application potential. Glycan was isolated from a medicinal mushroom, a macro fungus known as Ganoderma lucidum. This fungus is well known for its therapeutic value and it is known as Reishi mushroom in Japan and China. The glycan from this fungus were isolated and the structural composition was studied. By trial and error we isolated the compound and structurally identified as beta glucan. Having great potential it is worthwhile to study this molecule.
A simple strategy based on fibers coated with surfactant-functionalized multiwalled carbon nanotubes to improve the properties of solid-phase microextraction of phenols in aqueous solution
Authors: zhou xueqing , Xie Yanli , Zhao Zhendong , Fu Wenyan
Published: August 2019

A functionalized multiwalled carbon nanotube (MWCNT)-coated solid-phase microextraction (SPME) fiber was developed for concentrating analytes in aqueous samples. Sodium deoxycholate(NaDC) was used as a wrapping layer for non-covalent modification of MWCNTs. Non-covalent bonding between the MWCNTs and sodium deoxycholate changed the electrical and steric resistance of the MWCNTs, and improved their solubility and dispersibility. To investigate the capability of this MWCNTs/NaDC SPME fiber, it was applied to the analysis of phenols in aqueous solution. After extraction, the analytes were desorbed in an acetonitrile–water solution and analyzed using high-performance liquid chromatography. The MWCNTs/NaDC fiber exhibited a response two to six times that of a commercial fiber for phenols. The hydrogen interactions with the analytes and the large surface area of the MWCNTs facilitated analyte adsorption with good selectivity and reproducibility. Under the optimum extraction conditions, the MWCNTs/NaDC fiber had a good linear range (1–100 ng/mL), repeatability for the extractions (relative standard deviation = 4.9%–7.1%, n = 3), low limits of detection (0.15–0.30 ng/mL), and satisfactory recoveries (80.3%–95.4%). This is an accurate and cost-effective pretreatment method.
Analysis of ternary mixture of anti-Parkinsonism drugs by capillary electrophoresis in pharmaceutical dosage forms
Authors: Talaat Wael , Ahmed Hytham , Salama Nahla
Published: August 2019

A simple CZE method was developed for the analysis of ternary anti-Parkinsonism mixture, levodopa, carbidopa and entacapone. The compounds were simply separated and measured using an untreated fused-silica capillary with 75 μm internal diameter and 85 cm total length, with effective length of 70 cm.. Background electrolyte composed of 20 mM phosphate buffer of pH 7.5 was used under an applied voltage of 15 kV. Photodiode array detector (PDA) was used to identify each compound at different wavelength to obtain high sensitivity. The present method was conducted to the analysis of the ternary mixture in pharmaceutical preparations. The analytical results proved the linearity (r2 ≥ 0.9995), accuracy, precision (% RSD < 2).
Relative position of the central hole after EVO-ICL implantation for moderate to high myopia
Authors: He Xiaojian , niu lingling , Miao Huamao , zhao feng , Zhou Xingtao
Published: August 2019

Background: This study aimed to evaluate the relative position of the central hole (CH) of Evolution Visian Implantable Collamer Lens (EVO-ICL), the pupil center (CP), and the corneal center (CC) after implantation of EVO-ICLs for moderate to high myopia.
Methods: Eighty-nine eyes of forty-nine patients with moderate to high myopia were evaluated. The mean preoperative spherical equivalent (SE) was -12.58 ± 4.13D. A routine postoperative follow-up was performed within 1–12 months. Positions of the CH of EVO-ICLs, the CP and the CC were recorded using a slit lamp anterior segment photography system, and their relative distances were calculated with the Visio image analysis software.
Results: All surgeries were performed safely, and no complications were observed in follow-ups after a mean 4.3 ± 4.82 months. At the last follow-up, the safety index (postoperative CDVA/preoperative CDVA) was 1.23 ± 0.48, and the efficacy index (postoperative UDVA/preoperative CDVA) was 1.08 ± 0.31. The CH in 85 eyes (95.51%) was superior to the CC, with 47.19% (42/89) on the temporal side and 48.31% (43/89) on the nasal side. The CH in 84 eyes (94.38%) was located on the temporal side of the CP, with 56.18% (50/89) superior and 38.2% (34/89) inferior to the CP. The CP of eighty-five eyes (95.51%) was superior on the nasal side of the CC. On the defined x-axis, the average distance from the CH to CC was significantly shorter than the average distance from the CP to CC (p < 0.001).
Conclusions: An imperfect mismatch between the central hole of EVO-ICLs and the pupil center does not necessarily indicate ICL dislocation. Compared to the pupil center, the position of the central hole of EVO-ICL is closer to the corneal center.
Evaluation of early degeneration of cartilage in patients with anterior cruciate ligament injuries: analysis using urine CTX-II biomarker
Authors: Nicolini Alexandre Pedro , Mansur Nacime Salomao B , Dreyfuss Juliana Luporini , Krob Joseph J , Ejnisman Benno , Cohen Moises , Astur Diego Costa
Published: August 2019

Background:Anterior cruciate ligament (ACL) rupture occurs predominantly in young patients. About 30% of individuals with this lesion will present with osteoarthritis within 20 years following the trauma, despite successful treatment. This can be explained by metabolic changes occurring concomitantly with the trauma that results in the injury to this ligament. Using analysis of biomarkers related to cartilage degeneration, we aimed to determine that soon after the trauma leading to ACL rupture there are intra-articular metabolic changes in the knee that could lead to cartilage degeneration. Methods:A cross-sectional study was carried out in two groups: patients with an ACL ruptures and a control group (each group with ten male subjects, age range 18 – 35 years, body mass index below 30 kg/m2). In both groups, urine concentrations of a biomarker related to degradation of type II collagen (CTX-II) was measured. For the group with ACL rupture, a temporal relationship between time post-injury and amount of the biomarker was also examined. Results:There were significant differences in the concentrations of urinary CTX-II between the ACL group and the control group (p = 0.009). No significant relationship was observed between time of injury and the quantity of the biomarker. Conclusions:Patients with ACL injury had higher concentrations of urinary CTX-II biomarker than those with no ACL injury (p = 0.009). However, there was no correlation between the concentration of this biomarker and the elapsed time post-injury (p > 0.05). Keywords: osteoarthritis; biomarkers, ACL injury, CTX-II
The relationship between seasonal influenza and telephone triage for fever: A population-based study in Osaka, Japan
Authors: Katayama Yusuke , Kiyohara Kosuke , Kitamura Tetsuhisa , Ishida Kenichiro , Hirose Tomoya , Matsuyama Tasuku , Kiguchi Takeyuki , Shimazu Takeshi
Published: August 2019

Background: Replacing traditional surveillance with syndromic surveillance is one of the major interests in public health. However, it is unclear whether the number of influenza patients is associated with the number of telephone triages in Japan.
Methods: This retrospective, observational study was conducted over the six-year period between January 2012 to December 2017. We used the dataset of a telephone triage service in Osaka, Japan and the data on influenza patients published from the Information Center of Infectious Disease in Osaka prefecture. Using a linear regression model, we calculated Spearman’s rank-order coefficient and R 2 of the regression model to assess the relationship between the number of telephone triages for fever and the number of influenza patients in Osaka. Furthermore, we calculated Spearman’s rank-order coefficient and R 2 between the predicted weekly number of influenza patients from the linear regression model and the actual weekly number of influenza patients for each season (January-March, April-June, July-September, October-December).
Results: There were 465,971 patients with influenza, and the number of telephone triages for fever was 420,928 among 1,065,628 total telephone triages during the study period. Our analysis showed that the Spearman rank-order coefficient was 0.932 and R 2 and adjusted R 2 were 0.869 and 0.842, respectively. The highest Spearman rank-order coefficient was 0.896 ( P <0.001) and R 2 was 0.803 in January-March ( P <0.001).
Conclusion: In this population, we revealed a positive relationship between the number of influenza patients and the number of telephone triages for fever, especially in January-March.
Potential teratogenecity risk and prescription drug use among pregnant women attending maternal and child health clinic of Kemisse General Hospital, Northeastern, Ethiopia
Authors: Alemu Belete Kassa , Wolle Nesredin Nigatu
Published: August 2019

Background

Drug use during pregnancy requires special consideration because both fetus and the mother are affected. Drug teratogenicity is most likely to occur when drugs are taken during first trimester of pregnancy when fetal organs are formed. In addition, drugs at second and third trimester may affect the growth and functional development of the fetus or have toxic effect on fetal tissues.

Objective

The objective of this study was to assess potential teratogenecity risk and drug use pattern in Kemisse General Hospital.

Methods

An institution based cross sectional study was conducted by reviewing a one year medical records (from January 1, 2010 to December 31, 2011) of pregnant women attending maternal and child health clinic of the hospital. Systematic random sampling was employed to select a total of 263 pregnant women. Structured data abstraction format was used for collection of data and then data were coded, entered and analyzed by using Statistical Package for Social Sciences version 23.

Result

A total of 263 medical records of pregnant women were reviewed, of which 234 pregnant women were prescribed with a total of 430 prescription drugs. The average numbers of drugs per pregnant women was found to be 1.84. Most pregnant women 166 (63.2%) were in the third trimester and more than half of them (51.3%) were multigravida. The maximum number of drugs were prescribed in the second trimester 162 (37.67%) followed by third trimester 143(33.26%). Supplemental drugs were the most widely used medications 297 (69.07%) and followed by 82 (19.1%) drugs from category B; 54 (12.6%) drugs from category C; and the rest 7 (1.6%) drugs from category D. There was no any drug from category X.

Conclusion

Approximately one third of the pregnant women encountered with drugs from category B, C and D. However, there were no FDA category C and D drugs prescribed in first trimester. There was no drug utilized by pregnant women from FDA pregnancy risk category X.
Outbreak of Infections Caused by Shigella ﬂexneri 2a with ESBL-Producing and Quinolone-Resistance in a Mental Healthcare Center in China
Authors: Lu Tiantian , Zhang Chuanling , Chen Yan , Guo Yuanyu
Published: August 2019

An outbreak of bacillary dysentery occurred in the Xiaoshan Mental Healthcare Center from November 8 to 16, 2012. Eight strains of Shigella flexneri 2a (S. flexneri 2a) were isolated from the same ward. The aim of the investigation was to clarify the origin of outbreak. Rectal swabs or fecal specimens from 7 doctors, 15 nurses, 2 nursing workers, 3 canteen workers, as well as 18 swabs from environmental sample in the ward were screened for Shigella. Phenotypic analysis included standard microbiological identification techniques, serotyping and antimicrobial susceptibility testing. PCR and sequencing were used to characterize drug resistance and virulence genes. Pulsed field gel electrophoresis (PFGE) was carried out for all Shigella isolates. S.flexneri 2a with multidrug resistance was isolated from eight patients and one canteen worker, which carried multiple antibiotics resistance genes and virulence determinants. The results of PFGE confirmed that nine strains of S. flexneri 2a belonged to the same clone. It was suggested that the outbreak strain spread directly from person-person or indirectly from person-food-person from the canteen worker. The outbreak was controlled after quarantine of ill residents, replacement of antibiotics and improvement of hygienic condition.
Expression and epigenetic profile of different CRISPR-Cas9 efficiency clones
Authors: Liu Yin , Mei Shenglin , Wang Hongxiu , Wang Fang , Wang Ying , Ni Lili , Xu Minyin , Lang Zhongping , Xu Weijie , Zhou Beiye , Wu Yue , Qian Fengmin , Guo Yinjuan , Wu Xiaocui , Wang Nuan , Gao Rongliang , Zhang Peng , Yu Fangyou
Published: August 2019

CRISPR/Cas9 cleavage efficiency is crucial in a genomic editing experiment. However, the molecular mechanisms that underlie this cleavage difference remain unclear. In our study, we characterized genome-wide gene expression and epigenetic features in CRISPR-Cas9 low and high clones across 3 different cell lines. We show that Cas9 expression level is relatively higher in high efficiency clones. Notably, histone mark ChIP-seq data demonstrate that differential expressed genes also have a different acetylation of histone 3 at lysine 27 (H3K27ac) level. Finally, we observed that PARVA is an important gene that can enhance CRISPR-Cas9 efficiency.
‘Motivational work’: a qualitative study of preventive health dialogues in general practice
Authors: Broholm-Jørgensen Marie , Langkilde Siff Monrad , Tjørnhøj-Thomsen Tine , Pedersen Pia Vivian
Published: August 2019

Background

While treatment plays an important role in general practice, primary and secondary prevention of so-called health behavior diseases has become an urgent issue of health politics as well as an important task in general practice. Through an analytical lens of ‘motivational work’, we explore how preventive health dialogues unfold in Danish general practices, with the purpose of understanding the social interactions and temporal complexities embedded in preventive health dialogues.

Methods

The empirical material in this study was obtained through 10 observations of preventive health dialogues and 18 semi-structured interviews with patients and general practitioners. The TOF pilot study in 2016 made it possible to explore preventive health dialogues between GPs and patients in general practice. The intervention addressed early detection and prevention in general practice through an approach of population-based risk stratification.

Results

We found that both GPs and patients—in an interplay—affected motivational work in the health dialogues to occur as one-way communication characterized by biomedically based guidance, information, suggestions, and advice on risk factors. Our findings illustrate a tendency among GPs to do motivational work without facilitating dialogue, concerning neither the underlying social causes of the behavior nor the patients’ possibilities to change their health behavior. We furthermore found that patients took part in reproducing the biomedical and treatment-oriented focus in the clinical encounter. Patients’ perspectives and expectations with regard to the structure and content of the health dialogues influenced whether and how GPs sought to promote and awaken patients’ motivation to change health behavior.

Conclusion

Overall, our findings point to a discrepancy between a biomedical action perspective and the temporality of prevention, with the former lessening the dialogue and interaction between GP and patient.
Clinical and mutational spectrum of 4 Chinese families with glutaric aciduria type 1
Authors: Shi Xiaorong , Shao Qiaoyan , Zheng Aidong , Xie Wenghuang
Published: August 2019

Background To investigate clinical presentation and molecular aspects of five patients suffered from glutaric aciduria type I (GA-I ), a rare neurometabolic disorder caused by glutaryl-CoA dehydrogenase deficiency due to GCDH gene mutations. Methods All five patients were diagnosed by elevated urinary glutaric acid and GCDH gene analysis. Low protein diet supplemented with special formula, GABA analog and L-carnitine were initialed following laboratory confirmation of diagnosis. The clinical and biochemical features were analyzed, and mutational analysis of GCDH was conducted using Sanger sequencing. Results Clinical manifestations of 5 patients varied from macrocephaly to severe encephalopathy, with notably different phenotype between siblings with the same mutations. Three members present complex heterozygous mutations, while two sisters present homozygous mutations. Among them, four mutations in GCDH were identified (c.1133C>T 、c.1244-2A>C 、c.339delT 、c.406G>T). Of these four mutations, c.1244- 2A>C was found in four patients and c.339delT and c.1133C>T has not yet been reported until now. Conclusions In 5 Chinese patients with GA1, two novel mutations of GCDH gene were identified, which may expand the mutation spectrum of GCDH gene. What we found confirm that there is no correlation between clinical phenotype and genotype in GA-I patients, and c.1244-2A>C may be mutation hotspot in Southern China.
Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial
Authors: Gong Yahong , Xu Xiaohan , Wang Jin , Che Lu , Wang Weijia , Yi Jie
Published: August 2019

BackgroundSore throat is a remarkable complication after thyroid surgery with endotracheal tube (ETT). Many studies revealed that laryngeal mask airway (LMA) might reduce the incidence and severity of postoperative sore throat. However, little is known about the use of a flexible reinforced LMA (FLMA) in thyroid surgery. The purpose of this study was to explore the potential benefits of FLMA compared with ETT on postoperative sore throat.MethodsIn this prospective, single-blinded, randomized, controlled trial, ninety-six patients aged 20-80 years, scheduled for elective radical thyroidectomy under general anesthesia were enrolled. They were randomly divided into ETT group and FLMA group. All the included patients received total intravenous anesthesia (with propofol, fentanyl and rocuronium) and controlled mechanical ventilation during the surgery. Cuff pressure of ETT and FLMA were strictly controlled. Incidence and severity of postoperative sore throat, numbness and hoarseness at 1, 24, and 48 h after surgery was evaluated and compared between the two groups. Incidence and severity of buckling during extubation and the hemodynamic profile during intubation were also recorded and compared.ResultsThe incidence of sore throat and hoarseness was significantly lower in FLMA group than those in ETT group at 1h, 24h and 48h postoperatively, as well as the severity of sore throat. Compared to ETT group, there was a significantly lower incidence of buckling during extubation and less fluctuation of HR and BP at 1min and 3min after intubation in FLMA group.ConclusionsPostoperative sore throat and hoarseness was improved in patients undergoing thyroid surgery with FLMA when compared with ETT. The use of FLMA also achieved less buckling during extubation and better hemodynamic profiles during intubation.
Effect of topical or peribulbar analgesia on the incidence of oculocardiac reflex, postoperative pain and postoperative nausea and vomiting following vitreoretinal surgery under surgical pleth index-guided general anaesthesia.
Authors: Stasiowski Michal J , Pluta Aleksandra , Lyssek-Boron Anita , Szumera Izabela , Pieta Malgorzata , Kawka-Buszman Magdalena , Niewiadomska Ewa , Dobrowolski Dariusz , Krawczyk Lech
Published: August 2019

Background: Despite of the risk of postoperative intolerable pain perception (PIPP), vitreoretinal surgery (VRS) requires general anaesthesia (GA) in selected patients. Intraoperative use of opioid analgesics (OA) during GA carries the risk of postoperative nausea and vomiting (PONV). The surgical pleth index (SPI) optimises the intraoperative titration of OA. Regional anaesthesia techniques are combined with GA to minimize the intraoperative use of OA. We evaluated the benefit of preventive analgesia techniques combined with GA using SPI-guided fentanyl (FNT) administration on the incidence of PONV, oculocardiac reflex (OCR) and PIPP in patients undergoing VRS. Methods: One hundred and five patients undergoing VRS were randomly allocated to receive either GA with SPI-guided fentanyl (FNT) administration alone (GA group) or with preventive topical 2% proparacaine (topical anaesthesia (TA) group) or preoperative peribulbar block (PBB) using 0.5% bupivacaine with 2% lidocaine (PBB group). Fifteen patients were excluded due to problems with postoperative SPI measurement. Results: Preventive PBB resulted in intraoperative reduction in FNT requirement, with no influence on perioperative outcomes. Intraoperative SPI-guided FNT administration during GA resulted in OCR in 7.78%, PONV in 10% and PIPP in 13.5% of patients undergoing VRS. Intraoperative SPI-guided FNT administration blunted the perioperative effect of preventive PBB and TA in terms of the presence of PONV, OCR and PIPP.Conclusions: The utility of SPI-guided FNT administration during GA eliminated benefits of preventive analgesia with PBB and TA following VRS. We recommend using intraoperative SPI-guided FNT administration during GA to reduce the presence of OCR, PONV and PIPP following VRS. Trial registration: The trial was approved and registered by The Ethical Committee of Medical University of Silesia on 29th of September 2015, as well as the project was registered in the Clinical Trial Registry (SilesianMUKOAiIT2, NCT02973581)Key words: vitreoretineal surgery, general anaesthesia, peribulbar block, topical anaesthesia, surgical pleth index.
Patients with both cognitive impairment and solid cancer present increased insulin resistance
Authors: Gonda Kenji , Yaginuma Kenji , Rokkaku Yuichi , Horita Shoichiro , Maejima Yuko , Shimomura Kenju
Published: August 2019

Objective

In an aging population, an increase in elderly cancer patients with cognitive impairment is to be expected. Because cognitive impairment has a serious impact on quality of life of cancer patients, it is important to elucidate the possible association between cancer and cognitive impairment. Here, we focused on glucose metabolism as a factor that links cancer and cognitive impairment.

Results

A homeostasis model assessment was used to assess insulin resistance (HOMA-IR) and β-cell function (HOMA-B). HOMA-B showed no difference among patients with cancer, with dementia, and with both. However, there was a significant difference in HOMA-IR. In comparison with patients with only solid cancer, patients with only cognitive impairment and those with both cancer and cognitive impairment showed increased HOMA-IR value. Insulin resistance was increased in patients with cognitive impairment only and those with both cognitive impairment and solid cancer compared to cancer patients without cognitive impairment; however, β-cell function was not affected. The present data indicate that elderly cancer patients with a high HOMA-IR score may be in higher risk of developing cognitive impairment. Furthermore, early treatment to reduce insulin sensitivity may become the prevention of cognitive impairment.
Admission pattern, Clinical outcome and associated factors among patients admitted in medical intensive care unit at University of Gondar Comprehensive and Specialized Hospital, Northwest Ethiopia, 2019. A retrospective cross-sectional study.
Authors: Tesema Hailemariam Getachew , Lema Girmay Fitiwi , Mesfin Nebiyu , Fentie Demeke Yilkal , Arefayne Nurhussien Rizike
Published: August 2019

Objective: To determine the admission patterns, clinical outcomes and associated factors among patients admitted in medical intensive care unit (MICU).
Results: A total of 738 patients were admitted to MICU during September 2015- April 2019. Five hundred and four patients (68%) of all ICU admissions had complete data. Out of the 504 patients, 268 (53.2%) patients were females. Cardiovascular disease 182(36.1%) was the commonest categorical admission diagnosis. The overall mortality rate of the MICU was 38.7 %. In the multivariate analysis, mortality was associated with need for mechanical ventilation (AOR=5.87, 95% CI: 3.24 - 10.65) and abnormal mental status at admission (AOR = 2.8.8, 95% CI: 1.83-4.29). Patients who stayed less than four days in MICU are 5 times more likely to dies than who stayed(AOR= 5.58, 95% CI: 3.58- 8.69). In this study, the overall mortality was considerably high. Need for mechanical ventilator, length of ICU stay and mental status at admission were strongly associated with clinical outcome of patients admitted to MICU. Therefore, we recommend improving the acute critical care through the expansion of the care, supply emergency equipment’s and medications and implementation of admission protocols.
Key words: Admission, Intensive care unit, Length of stay, Mortality, Outcome
Knowledge of neonatal danger signs and associated factors among mothers who gave birth the last four months attending immunization services in Harar town public health facilities, Ethiopia
Authors: Tekulu Fissaha welay , Welay Fissaha Tekulu , Kassa Nega Assefa , Hadera Gebrekiros Aregawi , Assefa Natnael Etsay , Mengesha Meresa Berwo , Weldemariam Mulu Gebretsadik , Gebremeskel Senait Gebreslasie
Published: August 2019

Objective

The purpose of this study was to assess knowledge about neonatal danger signs and associated factors among mothers that gave birth in the last 4 months attending immunization services.Result

The study allowed 432 mothers to participate in the study. The knowledge score of neonatal danger signs was found [32.9% (95% CI: 28.9%, 37%)]. Mothers educated to secondary level were 4.9 times more likely to know about neonatal danger signs [(AOR=4.9, 95% CI: (1.15, 21). Similarly, mothers whose husband educated to college and above [AOR=4.95, 95% CI: (1.15, 21)], and being multipara mother [(AOR=2.59, 95% CI: (1.05, 6.6)], were significantly associated factors of good knowledge of mothers about neonatal danger signs.
The effects of a combination of high-protein diet and resistance training on short-term weight loss and long-term weight maintenance in overweight and obese Chinese people: a study protocol
Authors: Shaoyong Xu , Zhang Juan , Dong Yuxiang , Chen Ruikun , Xu Wenlei , Tan Zhijun , Gao Ling , Shang Lei
Published: August 2019

Background

It is very important for clinicians and dieticians to explore reasonable weight management strategies for obese people that address both short-term weight loss and subsequent weight maintenance. We hypothesized that resistance training combined with a high-protein diet would result in similar short-term weight loss but better long-term weight maintenance than either conventional low-fat diet control or high-protein diet alone.Methods/design

This is an 8-week randomized parallel controlled trial followed by a 24-week observational follow-up study. A 48-week supplementary follow-up study will be carried out if necessary. The study will be conducted between June 2019 and October 2020. The 90 overweight or obese participants will be randomly assigned to the conventional low-fat diet group, the high-protein diet group and the high-protein diet and resistance training combination group. Primary outcomes are body weight changes at week 8 and week 24 compared with the baseline level.Discussion

High-quality research on the effect of a high-protein diet combined resistance training on weight loss and weight maintenance is limited in Chinese population. Our study will provide a basis for obesity management in China, and promote the development of exercise and diet-related studies.Trials registration

ChiCTR1900023841, 14 June 2019
New Mechanistic Phosphorus Fertilizer Recommendation Model Based on Two Intrinsic Phosphorus Pools in Tropical Soils
Authors: Shuai Xiufu
Published: August 2019

No mechanistic model for phosphorus (P) fertilizer recommendation is available for nutrient management in tropical soils. Soil intrinsic P pools, including a weakly and a tightly adsorbed P pool, were proposed to quantify actual soil available P. The goal of this study was to develop a new mechanistic P fertilizer recommendation model based on the two pools. The public data set of a corn (Zea mays L.) field experiment was used to estimate the daily corn P uptake. Seven soils were used to demonstrate the effects of P‐sorption site density (PSSD) and desorption rate of the tightly adsorbed P pool on the P fertilizer recommendation. Dynamics of soil P pools in a corn–soil system were modeled based on the transformation between the pools, the daily crop P uptake, and P fertilizer added at the beginning of planting. The weakly adsorbed P pool was required to be positive to represent no constraint of crop P nutrition. Results showed that the derived P recommendation model was a linear model of the total crop P uptake minus the two pools with three different coefficients. The weakly adsorbed P pool was readily available for crop uptake. The coefficients of the total crop P uptake and the tightly adsorbed P pool were >1.0 and <1.0, respectively, and they changed slightly with PSSD but were dependent on the desorption rate. The coefficient of the total crop P uptake showed a maximum 1.679 at the desorption rate 0.0118 d−1.

Core Ideas

A P recommendation model was developed based on dynamic soil surface reaction and crop uptake.

Intrinsic weakly and tightly adsorbed P pools quantify dynamics of soil P supply.

P requirement was a linear function of crop uptake and initial values of P pools.

Model parameters were determined by soil P‐sorption site density and desorption rate.
Assessing the level of environmental information disclosure by listed companies on the stock market in Vietnam
Authors: Kim Tuyen Nguyen Thi , Tien Nguyen Ngoc , Mai Huong Nguyen Thi
Published: August 2019

The environmental information disclosure of enterprises listed on Vietnam’s stock market has been mandated by the Ministry of Finance of Vietnam according to Circular No. 155/2015/TT_BTC. Therefore, enterprises need to be responsible for announcing and interpreting financial and non-financial information about the environment to meet the needs of the Government and stakeholders. However, the level of environmental information disclosure depends on their business, company characteristics, compliance of the board of management, etc. This paper investigates and assesses the level of environmental information disclosure of the listed companies on the stock market in Vietnam. The study was conducted with 170 listed companies on the Hanoi Stock Exchange (HNX) and Ho Chi Minh City Stock Exchange (HOSE) through descriptive statistics and value testing methods and an in-depth interview. The research results have shown that in Vietnam, the level of enterprises announcing environmental information disclosure is still low. For example, materials and construction industry, food and beverage industry have less than 55% of enterprise disclosing environmental information. At the same time, the enterprises from environmentally sensitive sectors such as materials and construction, electricity, petroleum, gas, chemicals, etc., have more environmental information disclosure than other industries, and the environmental information published only focuses on the environmental debt, the amount of resources consumed, the number of environmental violations, environmental policies and objectives, etc.
Impact of Frequency Shift on Nonlinear Compensation Using Optical Phase Conjugation for M-QAM Signals
Authors: Duc Binh Nguyen , Van Dien Nguyen , The Quang Nguyen , Nhu Quynh Nguyen Quang , Phuoc Tien Ho , Van Tuan Nguyen , Tan Hung Nguyen
Published: August 2019

Nonlinear compensation using optical phase conjugation (OPC) have been considered a promising technique to increase the reach of high-speed fiber-optic transmission systems. OPC-based nonlinear compensation employs an optical phase conjugation located at a middle of the fiber link to generate a complexed conjugated signal with respect the signal in the first half of the link for propagation in the second half. OPC technique assumes a symmetry for signal propagating in the first and second half to obtain a perfect nonlinear and chromatic dispersion. However, as most of practical OPC schemes are realized by nonlinear effects such as four-wave mixing or a combination of second-harmonic generation and difference frequency generation, the frequency shift induced by OPC affects the signal symmetrical requirement for nonlinear compensation because the chromatic dispersion is different for the first and second half transmissions. In this paper, we investigate the impact of frequency shift on the nonlinear compensation using OPC for high symbol rate, high level modulation format signals. This will be important to understand the tolerance of the OPC techniques against such a practical condition for actual system implementations.
KONTRIBUSI TEORI IBN AL-SHĀṬIR DALAM PERKEMBANGAN TRADISI ILMIAH ASTRONOMI ISLAM
Authors: Sakirman S , Shabir Muslich
Published: August 2019

This paper traces the roots of the scientific tradition of astronomy in a classical century that marked the rise of Islamic civilization in the midst of Western darkness in a philosophical-historical perspective. The study focussed on translation activities in the eighth century to the peak of astronomical scientific activity that is divided into two major schools; the astronomical-mathematical school of the East and the astronomical-philosophical schools of the Western world to the Islamic Caliphate. The Greek astronomical tradition is basically dominated by Aristotelian thought that states that the universe is organized into a set of concentric spheres each carrying a star and spinning around the earth. The Earth is still and becomes the center of the universe. Ptolemy adopted the two basic principles of Aristotle, ie the earth dwells at the center of the universe and the motion of heavenly bodies must be represented by a set of perfectly uniform circular motions. From the results of historical studies on the development of Muslim astronomy in the classical century can be seen that the peak of scientific progress in the Western world can not be separated from the point of zenit for the advancement of science developed by Muslim scientists. Efforts made by Western scientists in enriching the astronomical treasury is inseparable from the step of translation through intensive scientific studies that gave birth to a variety of monumental works in the history of astronomy.

Tulisan ini melacak akar tradisi ilmiah astronomi pada abad klasik yang menandai majunya peradaban Islam di tengah-tengah kegelapan Barat dalam perspektif historis-filosofis. Kajian difokuskan pada aktivitas penerjemahan pada abad kedelapan hingga puncak kegiatan ilmiah astronomis yang terbagi dalam dua mazhab besar; mazhab astronomis-matematis di Timur dan mazhab astronomis-filosofis di dunia Barat pada kekhalifahan Islam. Tradisi astronomi Yunani pada dasarnya didominasi pemikiran Aristotelian yang menyatakan bahwa alam semesta diatur menjadi satu set bola konsentris masing-masing membawa bintang dan berputar di sekitar bumi. Bumi berposisi diam dan menjadi pusat alam semesta. Ptolemeus mengadopsi kedua prinsip dasar Aristoteles tersebut, yaitu bumi diam di pusat alam semesta dan gerak benda-benda langit harus diwakili oleh satu set gerakan melingkar sempurna yang seragam. Dari hasil kajian historis atas perkembangan astronomi muslim pada abad klasik dapat diketahui bahwa puncak kemajuan ilmu pengetahuan di dunia Barat tidak lepas dari titik zenit atas kemajuan ilmu pengetahuan yang dikembangkan oleh ilmuwan Muslim. Upaya yang dilakukan ilmuwan Barat dalam memperkaya khazanah astronomi tidak terlepas dari langkah penerjemahan melalui pengkajian ilmiah yang intensif sehingga melahirkan berbagai karya-karya monumental dalam sejarah astronomi.
Pengaruh Pendapatan Bagi Hasil dan Pemberian Bonus terhadap Loyalitas Nasabah di Bank Syariah Mandiri Kantor Cabang Sangatta
Authors: Khairi K , Nursalim Eko , Parno P
Published: August 2019

This type of research is descriptive quantitative. This study uses analytical techniques that include path analysis with the aim to find out the direct and indirect influence of independent variables on the dependent variables processing data using SPSS, simultaneous testing (F test) and individual testing (t test). The population in this study are customers in Bank Syariah Mandiri Sangatta Branch Office. And the number of samples taken by 98 respondents by using random sampling technique. The results showed that there is a significant influence between income sharing (X1) and bonus (X2) to customer loyalty (Y) either partially or simultaneously. From the results if the data is known value of correlation coefficient (R) of 0,542 with interpretation between 0,40 - 0,599 which means existence of positive relation between variable of revenue sharing and giving bonus to customer loyalty, and included in category strong enough. The results of this study indicate that the revenue-sharing variable and bonus giving contributes to customer loyalty variables with a total influence of 29.4% and the remaining 70.6% is likely determined by other factors and not examined in this study. And the path equation is Y = 0,366X1 + 0,297X2.
Kearifan Lokal di Pedesaan: Kajian Praktik Budaya Religi Di Desa Nyatnyono
Authors: Adinugraha Hendri Hermawan
Published: August 2019

One element of culture in Javanese society is belief or religion. Religion has two meanings: First, religion is a religion related to God, its teachings are revealed through prophets and revelations. The truth is absolutely inviolable based on the beliefs of the adherents. Second, religion are part of culture, to fulfill collective awareness and identity. Therefore, every society has a certain way and is different from one region to another in carrying out their beliefs. Nyatnyono village, for example, they have a firm belief held in the form of a ritual carried out on certain days inherited from their ancestors. In the context of this research, religion is not only a religion but also as a cultural phenomenon as well as local wisdom which is full of values practiced by its people. Based on this explanation, this study aims to describe religious culture as a form of local wisdom in the village of Nyatnyono in Semarang Regency. This research is a descriptive qualitative type of research. The results of this study indicate that there are many religious cultures that have been adopted into local wisdom for the people of Nyatnyono Village such as the iriban tradition, merti dusun, yasinan, nyadran (ruwahan), pengajian nuzul al-Qur’ān, syuronan, tirakatan, and so on. However, the tradition or habit that dominates in the village of Nyatnyono is the ziyarah of the tomb of Mbah Ḥasan Munadi and Mbah Ḥasan Dipuro and Mandi at Sendang Kalimah Ṭayyibah  and Sendang Amanah, where it has been a hereditary culture for the Nyatnyono Village and those cultures that deliver Nyatnyono Village as one of the religious tourism icons in Semarang Regency with visitors from various regions so as to create jobs for the local community and be able to increase the Regional Revenue of Semarang Regency
Progresivitas Hukum Kewarisan Beda Agama di Indonesia Berbasis Keadilan dan Maṣlahah
Authors: Rohmawati R
Published: August 2019

The Division of the inheritance of the most crucial of them, there is a difference of religion between the heirs and the muwarriṡ, both the difference when muwarriṡ was still alive or when a heir has died. Indonesia, Islamic law as contained in the compilation of Islamic law (KHI), have determined that religious differences can be a hindrance to each other can be inherited. Along with the development of the times, the provision in the KHI was not considered relevant to the needs of today's society, so the necessary progressive efforts to respond to the problem of Islamic inheritance laws in Indonesia. Complexity and plurality of society Indonesia demanding the Islamic jurist to do the renewal of the law, as the religious court judges has been made in resolving the different religious inheritance matters by using the rechtsvinding function justified by positive law and compile Islamic law, when there is no law that governs. The renewal of the law in the form of the granting of the estate to the heirs of muwarriṡ Muslims from non-Muslims and the granting of probate wajibah to non-muslim heirs of muwarriṡ of Islam. This is done for the sake of Justice and benefit of tegaknya in human life.