bluuebunny/crossref_metadata_2025 huggingface dataset:
Intelligence in Context manuscript preprint
Authors: Limeri Lisa
Published: January 2025

Mindset (beliefs about the malleability of intelligence) has been studied in a variety of contexts for decades. Recent research highlights the importance of contextual factors in moderating mindset’s impact on student outcomes. The commonly-used original mindset measure is context-general. Recently, a mindset measure that is specific to science and math undergraduates was developed: the Undergraduate Lay Theories of Abilities (ULTrA) Survey. I hypothesized that a context-specific measure of mindset would associate more strongly with undergraduates’ outcomes than a context-general measure. I surveyed 1,537 undergraduates with the shortened original mindset measure, ULTrA, and measures of outcomes (sense of belonging, goal orientation, self-handicapping, evaluative concern and intent to persist in science) and collected course grades. Structural equation modeling indicated that the fixed dimension of the ULTrA exhibited stronger and more consistent relationships with outcomes than the shortened original mindset measure and predicted unique variance in outcomes above and beyond what the original mindset measure accounted for. The academic outcomes (intent to persist and course grade) were significantly related to ULTrA, but not the original mindset measure. Our results provide evidence that the context-specific ULTrA survey can detect relationships with undergraduate outcomes that the context-general original mindset measure can fail to detect.
Transparency and Open Science Practices in Research on Emerging Adulthood
Authors: Nguyen Phuong Linh Le , Syed Moin
Published: January 2025

The replication crisis has become a major focus throughout the sciences, spurring discussions among researchers about the limits of the mainstream work produced in their fields. In response, there have been strong efforts towards developing solutions to address these limits, efforts that are broadly referred to as the open science movement. In this chapter, we highlight three core issues related to open science that are particularly important for producing and consuming research on emerging adulthood: 1) The importance of understanding and reducing research degrees of freedom across the research cycle; 2) the under-appreciated role of statistical power in quantitative studies, particularly when testing interaction effects; and 3) some of the unique challenges facing emerging adulthood researchers in adopting open science practices. Across the discussion, we provide concrete steps that researchers can take to promote the open science principles of transparency, credibility, reproducibility, and accessibility.
Strategies for Regulating Achievement Emotions: Conceptualization and Relations with University Students’ Emotions, Well-Being, and Health
Authors: Stockinger Kristina , Dresel Markus , Marsh Herb , Pekrun Reinhard
Published: January 2025

Background: Students’ achievement emotions profoundly influence their learning, academic performance, well-being, and educational trajectories. Understanding how students regulate these emotions is crucial for their academic flourishing.Aims: We examined students’ strategies for regulating three common achievement emotions (enjoyment, anxiety, boredom), and how these strategies relate to emotions, academic well-being, health problems, and achievement-related outcomes.Theoretical Framework: Our theoretical model of emotion regulation strategies is derived from the control-value theory of achievement emotions (Pekrun, 2006) and Harley et al.’s (2019) model of emotion regulation in achievement settings. It considers six groups of strategies: situation selection, social support, reappraisal, expression, suppression, and competence development. Samples: Participants included 350 (Study 1; Germany), 359 (Study 2; England), and 200 (Study 3; Germany) university students.Methods: Studies 1 and 2 were cross-sectional. Study 3 employed a five-wave prospective design and focused on course-specific achievement emotion regulation over one semester. We used a newly developed context- and emotion-specific measure of the six strategies targeting enjoyment, anxiety, and boredom (Regulation of Achievement Emotions Questionnaire, RAEQ). Results: Strategies were linked to students’ emotions, well-being, health, and academic achievement (perceived success, Studies 1 and 2; end-of-semester test scores, Study 3) across all three studies. Furthermore, achievement emotion regulation strategies were related to, but distinct from, general emotion regulation strategies.Conclusions: Findings highlight the importance of students’ regulation of both positive and negative emotions, suggest that emotion regulation is context-specific, and imply that reappraisal and competence development are especially adaptive. We discuss implications for educational practice and future research.
Tactical Breathing Leads to Better Police Performance in a Simulated Critical Incident
Authors: Granerud Thea , Nijhof Mona , Sandvik Asle Makoto , Sætrevik Bjørn
Published: February 2025

It has been suggested that tactical breathing may reduce acute stress for police officers and thus lead to more optimal performance in critical situations. We tested the effect of a brief intervention on task performance in a simulated training scenario. Ninety-six advanced police students participated in a preregistered between-group experiment during a simulated training scenario. Expert observers evaluated performance, and participants reported their level of stress. The results showed that stress was associated with lower performance. The participants that used tactical breathing performed better than the control group, while it did not change their self-reported stress. This could indicate that tactical breathing improves performance by increasing focus and attention.
Controlling for careless responding requires causal justification
Authors: Alsalti Taym , Cummins Jamie , Arslan Ruben C.
Published: February 2025

Careless responding is defined as a pattern of responding to survey items that reflects a latent construct distinct from—and disruptive of—the measurement of the primary construct of interest. In the social science literature, these response patterns are sometimes labeled “insufficient effort,” “unserious,” or “bogus, among other terms.”The issue of such responses has been gaining in relevance as research data are increasingly collected through anonymous online surveys. Standard practice calls for identifying careless responders and excluding them from the data. The common reasoning behind this approach is that such responses can bias “descriptive” statistics (e.g., sample means) and effect size estimates / measures of associations (e.g., correlations and standardised mean difference) as well as increase measurement error. When they confound our causal effect of interest, deleting or adjusting for careless responses is justified. However, using directed acyclic graphs (DAGs), we show that different careless responding patterns can plausibly take on the role of a mediator, a collider, or both simultaneously, among others. Given this, we argue that, in contrast to previous calls, there cannot be a general rule about how to deal with careless responses and that greater attention to their data-generating mechanism from a causal perspective is necessary.
As tecnologias habilitadoras da indústria 4.0 como facilitadoras do processo de transição para a economia circular no setor automotivo
Authors:   , Barderi Marcos Tavares
Published: January 2025

The Circular Economy has emerged as an alternative to decouple economic growth from environmental impacts. One of the industrial sectors that most affects the economy is the automotive sector, which traditionally consumes large amounts of natural resources and generates waste. In this context, Industry 4.0 brings technologies capable of facilitating the implementation of the Circular Economy. The general objective of this work is to develop a model based on contributions from Industry 4.0 enabling technologies for the Circular Economy in the automotive sector. The method applied is a case study with different Units of Analysis, carried out in a commercial vehicle manufacturing industry that is a reference in the implementation of Industry 4.0 enabling technologies. The results showed that it is possible to relate enabling technologies to the phases of the vehicle life cycle and to the ReSOLVE strategies of the Circular Economy. Additive Manufacturing promotes a smarter design of parts, reducing weight and volume of materials. In addition, it digitalizes the design process and eliminates the traditional supply chain, reducing fuel consumption and emissions. Collaborative Robots increase precision in manufacturing applications, reducing rework and waste.
Augmented Reality, through information in virtual environments, contributes to maintenance
and training activities, generating efficiency in the production process. Simulation tests
practices virtually before physical execution, reducing rework and consumption of natural
resources. Systems Integration facilitates data sharing between departments and suppliers,
promoting process efficiency and material circularity. The Internet of Things connects devices
to the web, creating a vast database that assists in decision-making and the development of new
initiatives. Cloud Computing facilitates the sharing of logistics and after-sales information,
promoting packaging reuse and eliminating the need for physical data centers. Big Data
Analysis generates opportunities from large volumes of data, and can provide insights into
initiatives involving dematerialization, use of alternative materials, and circularity options.
Cybersecurity is essential to protect digitized data, ensuring the integrity and availability of
information
Application of artificial intelligence to toxicological assessment of plant: a bibliometric analysis and future research plans
Authors: Busari Muibat Bolajoko
Published: February 2025

Artificial intelligence (AI) has gained attention in health science, with significant applications in the toxicological assessment of plants. However, a bibliometric analysis is essential to chart research trends and propose future advancements. This study explores key publications on AI’s role in plant toxicity assessment, identifying unresolved issues in pharmacological research. Articles from January 2008 to December 2023 were retrieved from the SCOPUS database, revealing a steady rise in publications, with a sharp increase from 2019 to 2023. A total of 75 research articles were analysed. The articles were categorised into four main clusters: AI applications, drug development, toxicity prediction models, and adverse drug event evaluations. ‘AI’ was the most frequently mentioned keyword, followed by ‘drug toxicity.’ Among 64 articles, the USA contributed 29, China 11, India 8, and the UK 4, with the UK having high citation rates. The findings highlight a growing trend toward AI-driven toxicity prediction in drug discovery. However, few studies provide definitive conclusions on AI’s potential in this field. The COVID-19 pandemic has heightened interest among researchers and policymakers. This study urges increased government and agency funding for AI-driven toxicity research. Advancing this field will enhance drug safety, reduce harmful testing, and promote sustainable plant use, aligning with SDGs 3, 12, and 15.
Exploring environmental, social and governance (ESG) in the halal industry in Brunei
Authors: Hamdani Humayra , Mohd Raffi Raihana
Published: February 2025

This article aims to explore the extent, approaches and challenges of Environmental, Social and Governance (ESG) principles’ incorporation into the halal industry with Brunei Darussalam as the case study. This is based on multiple factors, especially economic diversification. A qualitative approach with a case study analysis was employed, utilising solely library data on ESG and observational insights on Brunei. As a result, this study finds that it is possible to incorporate ESG within Brunei's halal industry. It comes with challenges such as low purchasing power due to the small population, unemployment issues, and perceptions of ESG centred around developed countries. Coupled with limited data, the solutions to the challenges are unknown. Thus, collaborative efforts from all stakeholders are required. Addressing these challenges could enable Brunei to align its halal industry with ESG principles for realising Wawasan Brunei 2035.
The Importance of Type D Personality for Mental Adjustment to Cancer in Patients with Colorectal Cancer
Authors: Pilarska Angelina Kaleta-
Published: February 2025

Background: Cancer diagnosis is a source of long-term stress for the patient. The patient's mental adjustment to the disease directly affects the quality of his life and may also determine the effectiveness of the final therapeutic effects. Determining the significance of Type D Personality for mental adjustment to cancer may have not only cognitive value, but also influence the improvement of preventive recommendations.
Material and methods: The study involved 200 patients diagnosed with colorectal cancer. During the study, the Author's Personal Questionnaire, the Mini-MAC questionnaire and the DS-14 were used.
Results: The majority of the respondents (56.4%) with Type D Personality present a Destructive Style of Mental Adjustment to Cancer Disease.
Conclusions: The significance of Type D Personality is evident after taking into account the presence of other cancer diseases, the patient's fitness level and alcohol consumption before the diagnosis of cancer in the case of the Destructive Style of Mental Adjustment to Cancer Disease dominating in the picture.
Role of Health Technology Assessment in Pharmaceutical Market Access in Developed Countries
Authors: Haider Rehan
Published: January 2025

Health technology evaluation (HTA) performs a pivotal role in facilitating the pharmaceutical marketplace to get admission to inside developed countries. This abstract delves into the importance of HTA on this context. In advanced countries, the rapid evolution of prescription drugs has led to complicated landscapes in which novel therapies abound. HTA, a multidisciplinary manner comparing medical, monetary, social, and ethical components of fitness technology, emerges as an imperative tool. usually, HTA promotes knowledgeable selection-making by using assessing a drug's scientific efficacy, protection profile, and comparative effectiveness against present remedies. using providing evidence-based insights, HTA aids regulatory agencies and reimbursement authorities in evaluating a pharmaceutical's ordinary cost proposition. Furthermore, HTA aligns with cost-containment goals. evolved nations grapple with escalating healthcare costs, necessitating cautious allocation of resources. HTA evaluates a drug's cost-effectiveness, assisting government decide whether the blessings justify the economic burden. This method safeguards healthcare sustainability while selling equitable patient access to revolutionary remedies. HTAs role extends past regulatory and financial issues. ethical dimensions, which include affected person options and societal implications, also are evaluated. HTA guarantees that approved prescription drugs are congruent with societal values and patient desires, fostering agree with inside the healthcare system.
4D Research and Development Model: Trends, Challenges, and Opportunities Review
Authors: Indaryanti Rosita Budi , Harsono Harsono , Sutama Sutama , Murtiyasa Budi , Soemardjoko Bambang
Published: January 2025

The 4D model—Define, Design, Develop, and Disseminate—is a widely recognized framework for research and development (R&D), particularly in educational innovation. This systematic literature review (SLR) examines the implementation trends, challenges, and opportunities of the 4D model across various fields, analyzing 50 peer-reviewed journal articles published between 2013 and 2023 using PRISMA guidelines. Results indicate that the 4D model is predominantly applied in educational contexts, such as curriculum design and instructional material development, with limited adoption in non-educational sectors. Major challenges include a lack of empirical validation and difficulties in adapting the model to multidisciplinary applications. Opportunities for enhancing the 4D model include integration with contemporary methodologies, such as agile approaches and artificial intelligence. This study provides recommendations for future research and practical insights to broaden the applicability and impact of the 4D model.
Implikasi Pandangan Filsafat Pragmatisme John Dewey Terhadap Praktik Pendidikan Serta Relevansinya Dengan Merdeka Belajar Kampus Merdeka
Authors: Ega Nasrudin  , Shalza Alifia Yasha  , Udin Supriadi
Published: January 2025

This study examines the implications of John Dewey's pragmatism philosophy views on educational practice along with its relevance to Merdeka Learning Merdeka Campus. A qualitative approach of literature study type is used in this research. The results of this study found that the involvement of students in participating in one of the programs offered and the process of training problem-solving skills in each form of the program make MBKM can be seen as pragmatic education. John Dewey's pragmatism education philosophy views education as a process of familiarizing individuals in overcoming every problem in their environment. Education should encourage students to have the skills to overcome existing problems. Apart from that, this research also describes how the implications of John Dewey's pragmatism education concept in educational practice. For students, they need to have useful skills by getting used to implementing learning using collaborative and interdisciplinary approaches in solving problems. For teachers, they need to apply the right learning approach method. The learning approach that is considered appropriate must have collaborative characteristics, emphasize interdisciplinary approaches, and train students in problem solving. For schools or policy makers, schools and or policy making institutions need to ensure that the curriculum implemented has encouraged students to get used to being actively involved in problem solving. The curriculum in this case presents situations where learners are directed to practice solving existing problems.
Optimalisasi Produk Lokal sebagai Daya Tarik Kampung Wisata Pakintelan Semarang
Authors: Aryaningtyas Aurilia Triani , Suwarti Suwarti , Wuntu Gana , Putriningsih Tiara Sanika Langsa , Putri Amelia Lufitta
Published: January 2025

This study examines the optimization of local products as the main attraction of Pakintelan Tourism Village in Semarang. The primary issues identified include inadequate promotion and infrastructure to support the potential of local products such as durian and bamboo  crafts. Through a qualitative approach and descriptive method, this research explores community involvement, collaboration with government and businesses, and challenges in utilizing local products. The findings indicate that local products have significant potential to enhance tourism appeal and local economy. However, limitations in infrastructure and promotion  remain major obstacles. Strategic recommedations include enhancing digital promotion, developing infrastructure, and fostering multi-stakeholder collaboration. The study also highlights the need for further research to evaluate the long-term impact of local product development initiatives on community welfare.
PENGEMBANGAN MEDIA PEMELAJARAN PAPAN VEKTOR UNTUK MENINGKATKAN MOTIVASI DAN MINAT BELAJAR SISWA
Authors: Taqiyyah Nabila Putri  , Khairunnisa Wahidah  , Hanifa Putri Ramadhani  , Dimas Wibowo  , Kairuddin
Published: February 2025

Penelitian ini bertujuan untuk mengembangkan media pembelajaran berupa papan vektor untuk meningkatkan motivasi dan minat belajar siswa pada materi penjumlahan vektor di kelas XI SMA Negeri 1 Percut Sei Tuan. Penelitian menggunakan metode Research and Development (R&D) dengan model pengembangan 4D (Define, Design, Develop, Disseminate). Validasi oleh ahli media dan materi menunjukkan hasil 100%, yang termasuk kategori "Sangat Layak". Uji coba pada 24 siswa kelas XI menunjukkan peningkatan hasil belajar dari nilai rata-rata pretest 50,4 menjadi 88,33 pada posttest, dengan tingkat ketuntasan meningkat dari 20,83% menjadi 95,83%. Angket respon siswa menunjukkan persentase rata-rata sebesar 79%, yang masuk kategori "Sangat Setuju", mencerminkan respons positif terhadap penggunaan papan vektor. Hasil penelitian membuktikan bahwa media pembelajaran papan vektor efektif, praktis, dan layak digunakan untuk memfasilitasi pemahaman konsep vektor secara interaktif dan aplikatif Hal ini dimaksudkan agar media ini dapat membantu menciptakan pengembangan pembelajaran matematika yang lebih kreatif dan menarik.
¿Feminismo o amor pasional? La vida emocional de Frida Kahlo a través de sus cartas
Authors: Verdugo Álvez María Nieves
Published: January 2025

Introducción: mexicana de nacimiento, Frida Kahlo se ha convertido en un icono del movimiento feminista a nivel internacional, y su figura ha sido estudiada desde diferentes prismas. Dentro de este marco, el presente trabajo se plantea la siguiente cuestión: ¿se puede estudiar ese carácter feminista a través del análisis de las emociones, como por ejemplo sus amores pasionales? Metodología: Esta investigación hace uso del análisis de la correspondencia privada de Frida Kahlo, examinando en ella el concepto de amor pasional, y con la intención de estudiar a la artista mexicana desde un nuevo punto de vista. Resultados: Tras realizar un breve repaso bibliográfico de la autora, se han analizado las cartas que Kahlo dirigió a tres de los hombres más influentes de su vida: Alejandro Gómez Arias, compañero durante su adolescencia; su esposo Diego Rivera, con el que contrajo matrimonio en dos ocasiones; y el fotógrafo Nickolas Muray, con quien mantuvo una relación en paralelo a su matrimonio con Rivera. Conclusiones: Se ha puesto de manifiesto que, a pesar del lado más pasional e irracional que Kahlo presenta en su correspondencia, esa visión no llega a contradecirse o sobreponerse a su imagen como icono feminista y de empoderamiento.
Музичні твори для дітей та юнацтва сучасного українського композитора Едуарда Бриліна
Authors:   Vinnytsia Mykhailo Kotsiubynskyi State Pedagogical University, Брилін Едуард
Published: January 2025

Збірник створений в пам’ять про талановитого композитора, педагога, вченого Вінничини – Едуарда Бриліна, який все своє коротке життя присвятив пропаганді українського музичного мистецтва. Представлений збірник вміщує різні за тематикою, характером і складністю вокальні та інструментальні твори для дітей дошкільного і шкільного віку, учнів музичних шкіл та студентів закладів мистецьких спеціальностей вищої та середньої освіти, сповнені натхненністю, яскравою образністю, емоційно-осмисленими переживаннями композитора.
Surgical versus conservative management of spinal cord cavernous malformations: a systematic review and comparative meta-analysis
Authors: Rios-Zermeno Jorge , Ghaith Abdul Karim , Navarro-Garcia de Llano Juan Pablo , El-Hajj Victor Gabriel , Ortega-Ruiz Omar R. , Greco Elena , Goyal Anshit , Ravindran Krishnan , Kumar Jeyan S. , Williams Lindsy N. , Bydon Mohamad , Tawk Rabih G.
Published: February 2025

OBJECTIVE

Spinal cord cavernous malformations (SCCMs) are rare vascular malformations with a capricious prognosis. Given the eloquent nature of the spinal cord, considerable surgical morbidity may be encountered. Therefore, conservative management has emerged as a valid alternative, especially for incidental lesions diagnosed on ubiquitous imaging. The aim of this systematic review and meta-analysis was to evaluate the safety and efficacy of surgical versus conservative management of SCCMs.

METHODS

Following PRISMA guidelines, this study included articles published in full-text form comparing the outcomes following conservative and surgical management of SCCMs. Collected variables included the total number of patients, spine level, resection, myelotomy, follow-up duration, bleeding, motor weakness, pain, bladder and/or bowel dysfunction, and neurological improvement or deterioration after discharge. The primary outcome of interest was long-term functional outcome.

RESULTS

Eleven articles comprising 515 patients were included, of whom 343 (66.6%) underwent resection and 172 (33.4%) were managed conservatively. Patients who underwent surgery were more likely to have preoperative motor deficits, hemorrhagic episodes, and bladder and/or bowel dysfunction, indicating increased disease severity. Resection was associated with significantly improved long-term functional outcomes (OR 3.27, 95% CI 1.72–6.24) compared with conservative management. There was no significant difference between the two groups regarding odds of long-term clinical deterioration (OR 1.03, 95% CI 0.35–3.03). However, the risk of hemorrhagic episodes during follow-up was higher in the conservative group (17.3%) compared with the surgical group (1.69%). The odds of hemorrhage during follow-up were lower in the surgical group, although not statistically significant (OR 0.24, 95% CI 0.05–1.05).

CONCLUSIONS

This study highlights that while surgical management of SCCMs is associated with better long-term functional outcomes and reduced risk of recurrent hemorrhage, treatment decisions must be carefully tailored to the individual patient, particularly given the potential risks associated with surgery. Conservative management, although less invasive, carries a nonnegligible risk of hemorrhage during follow-up, warranting close monitoring. These findings parallel management strategies used for brainstem cavernomas, for which surgery is reserved for cases with low surgical risk and worsening neurological symptoms. However, the limitations of current data, including selection bias and heterogeneity in reporting, emphasize the need for a multi-institutional registry to better define the natural history of SCCMs and inform future management strategies.
Does the crafted abdominal fat grafting technique completely eliminate risk of postoperative CSF leak in endonasal pituitary surgery? Technical note and preliminary clinical outcome
Authors: Lasica Nebojsa , Lesha Emal , Beckfort Neal S. , Arnautovic Kenan I.
Published: February 2025

OBJECTIVE

The endonasal transsphenoidal approach (ETA) developed over the years has become the standard of care for sellar and parasellar lesions. However, because it necessitates the removal of the skull base bone, it is often accompanied by CSF leakage. The authors aimed to provide technical nuances and analyze the results of their routine fat grafting technique after ETA.

METHODS

A consecutive patient cohort (2004–2024) of 168 patients who underwent ETA for sellar and parasellar lesions and the modified fat grafting technique for skull base repair were retrospectively reviewed.

RESULTS

Overall, combined ETA and transcranial approach (TCA) was performed in 7 (4.2%) patients, and 4 (2.4%) patients had prior transsphenoidal surgery. The size of the lesion was < 10 mm in 24 (14.3%) patients, 10–30 mm in 93 (55.4%), and > 30 mm in 51 (30.4%). Histopathological diagnoses were as follows: 154 (91.7%) pituitary adenomas, of which 45 (26.8%) were secreting; 8 (4.8%) Rathke’s cleft cysts; 2 (1.2%) inflammatory/autoimmune lesions; 2 (1.2%) craniopharyngiomas; 1 (0.6%) renal cell carcinoma metastasis; and 1 (0.6%) chordoma. Gross-total resection was achieved in 127 (75.6%) patients, near-total resection in 22 (13.1%), and subtotal resection/partial resection/biopsy in 19 (11.3%). Overall, 122 (72.6%) procedures had intraoperative CSF leakage. Postoperative CSF leakage was observed in 1 (0.6%) patient treated with a revision operation and regrafting with a slightly larger graft and lumbar drainage.

CONCLUSIONS

Even slight modifications in contemporary surgical techniques and the addition of an innovative approach may improve the treatment of sellar and parasellar lesions via ETA and reduce the risk of CSF leakage. The authors have developed and described a modified fat grafting technique with gradual crafting and preprocessing of the abdominal fat tissue for skull base repair, and they have demonstrated its effectiveness in significantly reducing the CSF leak rate. This technique enables adequate reconstruction of skull base defects with low donor-site complication rates and obviates the need for external lumbar drainage.
Contribution of watertight dural closure to prevention of postoperative cerebrospinal fluid leakage in endoscopic transnasal surgery for intradural lesions
Authors: Parmar Harisinh , Hasegawa Hirotaka , Shinya Yuki , Umekawa Motoyuki , Nishijima Hironobu , Kondo Kenji , Ono Hideaki , Hanakita Shunya , Saito Nobuhito
Published: February 2025

OBJECTIVE

The goal of this study was to evaluate the efficacy of watertight dural closure (WTDC) in preventing postoperative CSF leakage during extended endoscopic transnasal surgery (ETS) for skull base tumors, while preserving sinonasal quality by omitting the routine use of a nasoseptal flap.

METHODS

This retrospective study included 28 patients who underwent ETS and experienced Esposito grade 3 CSF leakage at a single institution between June 2022 and June 2024. WTDC was performed using fascia lata grafts and various suturing techniques. Surgical videos and electronic medical records were reviewed to assess suturing times and postoperative outcomes. The efficacy of WTDC in preventing CSF leakage was evaluated, and the technical aspects of the procedure were analyzed.

RESULTS

Among the 28 patients (14 female, 14 male), WTDC was successfully achieved in 14 cases, with near-watertight closure in the remaining 14. The average suturing time decreased with experience, showing a trend of improved efficiency. No postoperative CSF leaks were observed, and 1 case of postoperative meningitis resolved without sequelae. Despite significant risk factors for CSF leakage, WTDC was effective in all patients without the routine use of lumbar drainage.

CONCLUSIONS

WTDC in ETS is a reliable method for preventing postoperative CSF leakage, particularly in complex skull base surgeries with high-risk factors. This technique avoids the complications associated with nasoseptal flap use, preserves sinonasal quality, and reduces the need for lumbar drainage, making it a valuable option for skull base reconstruction.
Noncontrast imaging for the surveillance of treated and untreated meningiomas
Authors: Nguyen Lana V. , Kam Ning M. , Li Simon J. , Lee Jean , McKay Hamish , Jones Randall , Sutherland Tom , Smith Paul , Gogos Andrew J.
Published: February 2025

OBJECTIVE

Patients with meningiomas require serial MRI for surveillance of tumor size and growth rate. The cost and resource requirements for contrast-enhanced MRI include intravenous cannulation, the contrast agent, risk of adverse reaction, and the time needed to acquire, review, and report the additional sequences. With repeated doses, gadolinium is known to accumulate in neural tissues. The authors compared the correlation and accuracy of axial T2-weighted imaging (T2WI) sequences alone for assessing tumor growth, dimensions, and dural venous sinus invasion compared with the current clinical practice of assessing both contrast-enhanced T1-weighted imaging (CE-T1WI) and T2WI sequences.

METHODS

The authors retrospectively identified 136 adult patients (65 patients with treated and 71 patients with untreated meningiomas) with two MRI scans obtained at least 6 months apart. For each patient, the two CE-T1WI sequences separated by time were paired, as were the two T2WI sequences, and assessed independently. The paired scans were assessed by a neuroradiologist and advanced radiology trainee blinded to clinical data. Tumor location, dimensions, growth, and venous invasion were evaluated. Peritumoral edema was assessed on T2WI only. Agreement between assessments on both CE-T1WI and T2WI sequences compared with T2WI alone was evaluated using Cohen’s kappa (κ), the intraclass correlation coefficient (ICC), and Bland-Altman plots.

RESULTS

Growth was detected in 36 tumors on T2WI compared with 39 when both CE-T1WI and T2WI were assessed. Growth assessed on T2WI alone showed near-perfect agreement with growth assessed on CE-T1WI and T2WI together (κ = 0.945). T2WI alone had an accuracy of 97.8%, specificity of 100%, and sensitivity of 92.3%. Interrater correlation between the radiologists for tumor dimensions was good to excellent (ICC > 0.843). Intrarater agreement between T2WI and CE-T1WI measurements of anteroposterior and transverse tumor dimensions was good (ICC > 0.883 for observer 1, > 0.767 for observer 2). There was substantial agreement between venous invasion on T2WI and both CE-T1WI and T2WI (κ = 0.771). Subgroup analysis for skull base (58.1%), treated (47.8%), and large (> 20-mm diameter; 38.2%) meningiomas did not show any significant difference in agreement between T2WI only and CE-T1WI and T2WI assessments of growth, venous invasion, or tumor dimension.

CONCLUSIONS

In patients with treated and untreated meningiomas, unenhanced T2WI can assess tumor dimensions, detect growth, and detect venous invasion with comparable reliability and accuracy to the current clinical practice of using both CE-T1WI and T2WI.
Ultrasound-guided Hydrostatic Reduction of Acute Intussusception in Children at a Tertiary Care Center: An Observational Study
Authors: Yadav Ajay Kumar , Yadav Neha , Dev Binit , Dahal Sonia , Yadav Rohit Prasad , Taparia Sushil , Pathak Hiramani
Published: February 2025

Introduction: Intussusception is common cause of acute emergency responsible for bowel obstruction in infants and toddlers with peak age of incidence between 6-9 months. Ultrasound is imaging modality of choice for diagnosis of intussusception and ultrasound guided hydrostatic enema reduction is standard, nonsurgical, internationally preferred treatment modality for uncomplicated pediatric intussusceptions. This study was aimed to find the outcome of the procedure.Methods: An observational cross-section was carried in a tertiary care center in children presenting with intussusception. Ultrasoud guided hydrostatic reduction was done in all radiologically confirmed intussusception in children presenting to our tertiary hospital from February 2023 to July 2024 fulfilling the inclusion criteria after proper resuscitation. Patients having marked abdominal distension with features of peritonitis were excluded from the study. Ethical approval was obtained from Institutional Review Committee (Reference number: 287/2023). Results: Total 81 patients with 84 intussusceptions underwent ultrasound guided hydrostatic reduction with male to female ratio of 2.86 and mean age 9.49±8.43 months. Hydrostatic reduction was successful in 78 (92.85%) cases. Among successful reductions, 3 (3.84%) patients had recurrence and repeat successful hydrostatic reduction was done. Presenting complain seen were abdominal pain 81 (100%) , vomiting 72 (88.89%). Ileocolic intussusception was seen in 74 (88.09%). Conclusions: The success rate of ultrasound-guided hydrostatic reduction using normal saline for uncomplicated intussusception was consistent with findings from previous studies conducted in similar settings, which utilized both hydrostatic and pneumatic reduction methods.
Prevalence of Dentinal Hypersensitivity among Dental Patients Visiting Tertiary Care Center: An Observational Study
Authors: Ghimire Saru , Ghimire Sagar , Dahal Samarika , Dahal Sirjana , Paudel Neetika , Paudel Prayash
Published: February 2025

Introduction: Dentinal hypersensitivity is a widespread condition characterized by a brief, sharp pain arising from exposed dentin in response to external stimuli, which cannot be linked to any other dental conditions. This study aimed to estimate the prevalence of dentinal hypersensitivity among patients attending a tertiary health care center.Methods: A observational cross-section study was conducted, involving 376 patients aged 10-70 years who visited a tertiary care center. Convenience sampling was employed to select participants, and the prevalence of dentinal hypersensitivity was assessed through a questionnaire. Data were collected from the Department of Oral Medicine and Radiology after obtaining ethical approval Institutional Review Committee (Reference number: 385 (6-11) E2 079/80). The analysis was performed using Microsoft Excel, and descriptive statistics were reported . Results: There were 376 patients in the study and the prevlence of dentin hypersensitivity wasa 236 (62.77%; CI 95%: 57.66%-67.67%). Among those diagnosed, 138 (73.02%) were male, and 98 (52.41%) were female. The age-specific prevalence was found to be 30 (50.85%) in patients aged 10-19 years, 73 (63.48%) in those aged 20-29 years, 42 (53.16%) in patients aged 30-39 years, 23 (51.11%) in those aged 40-49 years. Conclusions: This study identified a high prevalence of dentin hypersensitivity among the patient population, with variations observed across different age and sex groups.
Prevalence of Osteoporosis in Patients with Distal Radius Fracture from Low-energy Trauma: An Observational Study
Authors: Kandel Manoj , Shrestha Sarik Kumar , Paudel Krishna Prasad , Panta Sunil , Banjade Deepak , Syangtan Ramesh , Thapa Sushil
Published: February 2025

Introduction: Osteoporosis is characterized by low bone mass, leading to enhanced bone fragility. Low-energy fractures of distal radius are related to osteoporosis and is therefore related to increased risk of subsequent hip fractures. The objective of this study was to study the prevalence of osteoporosis in patients with distal radius fracture from low-energy trauma. This will emphasise the need to investigate these patients for osteoporosis and make practitioners should be aware of the possibility of osteoporosis in such patients. Methods: This observational cross-section study evaluated the prevalence of osteoporosis in patients with distal radius fracture from low-energy trauma among patients presenting to tertiary level hospital of Nepal from October 2022 to September 2023.The participants’ demographic data, mechanism of injury, BMD values and T-score values were recorded and diagnosis of osteoporosis and osteopenia was made according to WHO diagnostic criteria. Ethical approval was taken from Institutional Review Committee (Reference Number: 079/80-015).Results: The study involved 96 patients with mean age of 68.27±4.09 years. The mean BMD among the participants was 0.69±0.02 and the mean T-score was -2.75±0.23. Diagnosis of osteoporosis was made in 88 (91.67%) patients and diagnosis of osteopenia was made in 8 (8.33%) patients based on the T-score using the WHO criteria. Of the 88n(%) patients who met the diagnosis of osteoporosis, only 45 (46.88%) patients had started treatment with bisphosphonates for osteoporosis.Conclusions: We have found a high prevalence of osteoporosis among patients with low-energy distal radius fracture.
Depression among Elderly of Chhayanath Rara Municipality, Mugu, Nepal: An Observational Study
Authors: Malla Nabina , Poudel Lisasha , Pokhrel Sushma , Chaudhary Vidya , Mali Prajita
Published: February 2025

Introduction: Depression is an important public health issue responsible for considerable morbidity and mortality among elderly. There were very few studies related with depression among elderly from rural community of Nepal. The objectives were to assess depression among elderly in Chhayanath Rara municipality.Methods: An observational cross-section study was conducted among 387 elderly through face-to-face interviews by using Geriatric Depression Scale-short scale (GSD 15) in a municipality of Nepal. Ethical Approval was taken from Institutional Review Committee (Reference Number: 079/80-015 ). Data were entered and analyzed into SPSS version 20. Descriptive statistics was employed to assess the prevalence of elderly depression.Results: The prevalence of depression among elderly was found to be 282 (72.87%; 95% CI: 68.44-77.30). Of those, 124 (32.04%) experienced mild depression, 115 (29.72%) had moderate depression, and 43 (11.11%) suffered from severe depression.Conclusions: The prevalence of depression in elderly was found higher compared to previous studies and other population.
Lymph node Yield in Apical Tissue During Triangle Operation While Doing Whipples Operation: An Observational Study
Authors: Maharjan Dhiresh Kumar , Pudasaini Prashant , Acharya Bidur Prasad , Limbu Yugal , Ghimire Roshan , Thapa Prabin BIkram
Published: February 2025

Introduction: The "TRIANGLE operation" involves the en-bloc removal of the tumor and the entire "mesopancreas" from the triangle-shaped space bounded by the superior mesenteric artery, coeliac trunk, and portal vein. This study assessed lymph node yield in apical tissue during the triangle operation.Methods: An observational cross-section study was conducted for two years at the Department of Gastrointestinal and General Surgery at a tertiary care center of Nepal. from 15th March 2022 to 15th March 2024. The operative procedure included pancreaticoduodenectomy or Whipple’s operation. Total sampling was done. Postoperative outcome and lymph node yeild of the surgeries were studied. Ethical approval was taken from the Institutional Review Committee (Reference No-1102202204).Results: A total of 56 patients underwent pancreaticoduodenectomy along with a triangle operation. The mean age of the patients was 56.38±14.79 years. Male: Female ratio was 1.2:1. Mean preoperative BMI was 24.41±4.72. The mean total lymph node yield was 20.95±8.57. Nineteen patients had a positive lymph node yield in the triangle tissue. The mean triangle lymph node yield was 10.59±4.92, and the mean positive lymph node was 2.58 ±1.64. Among 56 patients, nine patients had both apical margin and the rest of the triangle tissue margin positive. Ten patients had negative apical tissue margins, but the rest of the triangle tissue was positive, whereas, in thirty-seven patients, both the apical tissue and the rest of the triangle circumferential resection margin tissue were negative.Conclusions: This study emphasizes the importance of the inclusion of apical tissue dissection at the confluence of SMA and coeliac trunk to achieve R0 resection. However, a long-term follow is awaited.
Primary Intracranial Adenoid Cystic Carcinoma: A Case Report
Authors: Maharjan Pralisha , Aryal Gopi , Rana Reena
Published: February 2025

Adenoid cystic carcinoma (ACC) is a rare slow-growing but aggressive malignant tumor arising from the epithelial cells of mucous-secreting glands. Primary intracranial ACC is one of the rarest entity. We report a case of a 61 years old male presenting with difficulty in swallowing, slurring of speech, generalized body weakness. Patient had residual right cerebellopontine angle (CPA) mass causing midline shift and fourth ventricular obstruction on MRI. Patient underwent right retrosigmoid craniotomy with excision of CPA mass. Histopathological examination confirmed the case as primary intracranial ACC.
Klippel–Trenaunay Syndrome in the Distal Part of the Unilateral Upper Limb and Venous Deficiency: A Case Report
Authors: Maharjan Beenu , Liu Lian , Liu Xu , Liu Qingfeng , Jiang Xian
Published: February 2025

Klippel-Trenaunay Syndrome is a rare congenital disorder characterized by a triad of symptoms-capillary malformations, venous abnormalities, and hypertrophy of bones and soft tissues. The syndrome often presents with port wine stains, varicose veins, and limb hypertrophy, which can lead to significant complications such as venous thromboembolism and bleeding. We present a case of a 13 ` year female, with erythema in left upper limb and shoulder since birth.. An effective treatment method was employed, which incorporated a multidisciplinary team of experts specialized in various fields of dermatology and vascular surgery, all working collaboratively with the patient's well-being at the core of their efforts. This approach emphasized a personalized strategy based on the patient's preferences.
Sytuacja kościoła w okupowanej Polsce w świetle wojennej korespondencji prymasa Augusta Hlonda z bp. Józefem Gawliną
Authors: Bednarski ks. Damian
Published: January 2025

Ścisła współpraca Augusta Hlonda, prymasa Polski, oraz bp. Józefa Gawliny, przedwojennego biskupa polowego Wojska Polskiego, trwała przez prawie ćwierć wieku. W ostatnim czasie przygotowano do druku drugie, uzupełnione wydanie ich korespondencji z okresu 1924-1948. Dzięki wnikliwej kwerendzie w kilku archiwach udało się w ostatnich latach odnaleźć wiele listów obu hierarchów z okresu II wojny światowej. Niniejszy artykuł prezentuje genezę dokumentów, ich losy, a w części zasadniczej – analizę tekstów, przeprowadzoną w celu zrozumienia tego, jaka była wiedza biskupa i prymasa o sytuacji panującej w okupowanej Polsce, jakie zabiegi podejmowali, dążąc do uwrażliwienia Stolicy Apostolskiej na te problemy oraz na kontakty z duchowieństwem pozostającym w ojczyźnie. W tekście wyodrębniono korespondencję z okresu pobytu prymasa w Rzymie (do czerwca 1940 roku) oraz z okresu jego pobytu w Lourdes (do lutego 1942 roku). Później kontakt między hierarchami został przerwany, gdyż bp. J. Gawlina udał się Wschód, by organizować duszpasterstwo Armii Polskiej na terenie ZSRR, a prymas A. Hlond został przez Niemców internowany.
Wojenne straty materialne polskiej prowincji redemptorystów w latach 1939-1945 na przykładzie klasztorów w Toruniu i Warszawie
Authors: Sadowski CSsR O. Maciej
Published: January 2025

Niniejszy artykuł prezentuje straty materialne dwóch spośród ośmiu erygowanych przed wybuchem II wojny świtowej klasztorów polskich redemptorystów. Wśród nich pierwszym obiektem niemieckiej rekwizycji był dom na toruńskich Bielanach, stanowiący również siedzibą juwenatu, czyli niższego seminarium duchownego polskich redemptorystów. Klasztor w Toruniu został poddany całkowitej rekwizycji przez Niemców już w pierwszych dniach wojny obronnej, a wywłaszczenie redemptorystów było precedensowym przykładem nowej sytuacji majątkowej, w jakiej znalazł się Kościół na Pomorzu, wcielonym do Rzeszy. Stan trwającej ponad cztery lata konfiskaty klasztoru toruńskiego został przez niemieckie władze usankcjonowany bezprawnymi aktami okupacyjnej administracji. Dzieła zniszczenia wewnętrznej struktury klasztoru, a przede wszystkim biblioteki i wyposażenia gimnazjalnych pracowni toruńskiego juwenatu, dopełnili żołnierze sowieccy po wyparciu z miasta Niemców  od lutego do kwietnia 1945 roku. W archiwach państwowych i zakonnych zachowały się szczegółowe rejestry i kwestionariusze poniesionych przez toruńskich redemptorystów szkód wojennych. Drugim przykładem wojennej hekatomby dla Polskiej Prowincji Redemptorystów są losy klasztoru i kościoła na warszawskiej Woli, przy ul. Karolkowej. Ta placówka nie została doświadczona stratami przez cały okres wojny, aż do tragicznych wydarzeń 5-6 sierpnia 1944 roku, kiedy to podczas tzw. rzezi Woli Niemcy dokonali masowej egzekucji całej wspólnoty warszawskich redemptorystów. Ich los podzielił w następnych tygodniach zarówno klasztor, jak i kościół pw. św. Klemensa Hofbauera. Zostały one bowiem przez Niemców ograbione i niemal doszczętnie spalone. Skalę zniszczeń warszawskiej fundacji obrazują dobitnie prace rekonstrukcyjne prowadzone w latach 1945-1946 pod egidą Biura Odbudowy Stolicy.