bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural basis for the bypass of the major oxaliplatin–DNA adducts by human DNA polymerase η
Authors: Ouzon-Shubeita Hala , Baker Meghan , Koag Myong-Chul , Lee Seongmin
Published: February 2019

Oxaliplatin, together with cisplatin, is among the most important drugs used in cancer chemotherapy. Oxaliplatin, which contains a bulky diaminocyclohexane (DACH) moiety, kills cancer cells mainly by producing (DACH)Pt–GpG intrastrand cross-links that impede transcription. The Pt–GpG tolerance by translesion DNA synthesis (TLS) polymerases contributes to the resistance of tumors to platinum-based chemotherapy. In particular, human DNA polymerase η (Polη) readily bypasses Pt–GpG adducts. While many structural studies have addressed how TLS polymerases interact with cisplatin–DNA adducts, a structure of DNA polymerase in complex with oxaliplatin–DNA adducts has not been reported, limiting our understanding of bypass of the bulky (DACH)Pt–GpG lesion by TLS polymerases. Herein, we report the first structure of DNA polymerase bound to oxaliplatinated DNA. We determined a crystal structure of Polη incorporating dCTP opposite the 3′G of the (DACH)Pt–GpG, which provides insights into accurate, efficient bypass of the oxaliplatin–GpG adducts by TLS polymerases. In the catalytic site of Polη, the 3′G of the (DACH)Pt–GpG formed three Watson–Crick hydrogen bonds with incoming dCTP and the primer terminus 3′-OH was optimally positioned for nucleotidyl transfer. To accommodate the bulky (DACH)Pt–GpG lesion, the Val59–Trp64 loop in the finger domain of Polη shifted from the positions observed in the corresponding Polη–cisplatin–GpG and undamaged structures, suggesting that the flexibility of the Val59–Trp64 loop allows the enzyme's bypass of the (DACH)Pt–GpG adducts. Overall, the Polη–oxaliplatin–GpG structure provides a structural basis for TLS-mediated bypass of the major oxaliplatin–DNA adducts and insights into resistance to platinum-based chemotherapy in humans.
ADP-ribosylation and intracellular traffic: an emerging role for PARP enzymes
Authors: Grimaldi Giovanna , Corda Daniela
Published: February 2019

ADP-ribosylation is an ancient and reversible post-translational modification (PTM) of proteins, in which the ADP-ribose moiety is transferred from NAD+ to target proteins by members of poly-ADP-ribosyl polymerase (PARP) family. The 17 members of this family have been involved in a variety of cellular functions, where their regulatory roles are exerted through the modification of specific substrates, whose identification is crucial to fully define the contribution of this PTM. Evidence of the role of the PARPs is now available both in the context of physiological processes and of cell responses to stress or starvation. An emerging role of the PARPs is their control of intracellular transport, as it is the case for tankyrases/PARP5 and PARP12. Here, we discuss the evidence pointing at this novel aspect of PARPs-dependent cell regulation.
Hybrid optimisation method of sparse FIR DFEs based on reweighted ℓ1‐norm minimisation and greedy algorithms
Authors: Yu Lihong , Zhao Jiaxiang
Published: February 2019

The finite‐impulse‐response (FIR) decision feedback equalisers (DFEs) with a large number of taps are used to eliminate the intersymbol interference. In this Letter, a hybrid optimisation approach based on reweighted ℓ1‐norm minimisation and the greedy algorithm is proposed to get a better estimation of the non‐zero taps. First, the authors transform the problem of designing sparse FIR multiple‐input multiple‐output DFEs into an ℓ0‐norm minimisation problem, then use the proposed approach, which involves two stages as the preliminary selection of non‐zero tap positions and re‐optimisation with non‐zero taps, to determine the positions and values of the non‐zero taps for the FIR DFEs. The simulation results demonstrate the effectiveness of the proposed hybrid optimisation approach.
Opportunistic source‐pair selection method with imperfect channel state information for multiuser bi‐directional relaying networks
Authors: Ozduran Volkan , Yarman Bekir Siddik Binboga , Cioffi John M.
Published: February 2019

This study investigates the impact of imperfect channel state information that is caused by feedback delay with time‐variant channels and also by channel estimation errors with an opportunistic source‐pair selection strategy. The investigation considers multi‐user bi‐directional wireless relaying networks. The opportunistic source‐pair selection strategy selects the appropriate source‐pair node among N available nodes. The selection strategy is based on each source pair's maximum sum‐rate in each time slot. According to analytical, asymptotic, and Monte–Carlo simulation results, the opportunistic source‐pair selection strategy, besides achieving a near‐optimal solution for inter‐cell interference that is caused by other user‐pairs in the system model, also achieves diversity order in high signal‐to‐noise regimes. Moreover, the opportunistic source‐pair selection strategy outperforms the max–min‐based selection strategy in such a system model. Results also show that feedback delay degrades the achievable diversity order from N to 0 while affecting coding gain. The results also show that the channel estimation error case does not affect the achievable diversity order, but it does affect the system coding gain in low‐signal‐to‐noise regimes. Moreover, the channel estimation error effects upon system coding gain become negligible at high‐signal‐to‐noise regimes.
Channel estimation for 3D MIMO system based on LOS/NLOS identification
Authors: Xiang Minshan , Chang Yongyu , Zeng Tianyi
Published: February 2019

Channel estimation is one of the most important parts in three‐dimensional multiple‐input multiple‐output (3D MIMO) systems. The characteristics of non‐line‐of‐sight (NLOS) channel and line‐of‐sight (LOS) channel are different in 3D MIMO systems. If the same channel estimation scheme is used in LOS case as NLOS, the performance of estimation will be bad. In outdoor propagation environment, 3D MIMO channels between closely located antennas share the same delay support in temporal domain. With those prior knowledge, in this study, a new channel estimation scheme is proposed. The proposed scheme can be divided into two processes. First, it is needed to identify the received sounding reference signal whether is LOS or NLOS propagation. Then, different enhanced DFT‐based channel estimation schemes are proposed separately according to the identification results. Simulation results verify the proposed algorithm outperforms traditional discrete Fourier transform (DFT)‐based channel estimation. At signal‐to‐noise ratio of 20 dB, the proposed algorithm has 17.7 and 35.7% improvement in NLOS case and LOS case separately in terms of normalised mean squared error compared with traditional DFT‐based channel estimation scheme, and is achieved with additional liner complexity.
EEFCM‐DE: energy‐efficient clustering based on fuzzy C means and differential evolution algorithm in WSNs
Authors: Sharma Richa , Vashisht Vasudha , Singh Umang
Published: February 2019

Efficient energy utilisation is a fundamental challenge that needs to be dealt with while deploying a wireless sensor network (WSN). These networks consist of thousands of small‐sized battery‐operated devices called sensors. Sensors are resource‐constrained devices, and hence have very limited energy available with them. By lessening the energy usage of these nodes, the life span of the whole network can be enhanced up to a great extent. Clustering of WSNs is a speedily flourishing research area. In clustered WSNs, the major concerns are choosing an appropriate number of clusters and then selecting a coordinator node called cluster head (CH) within each formed cluster. This study introduces a hybrid energy‐efficient clustering based on fuzzy C means and differential evolution algorithm (EEFCM‐DE) based on fuzzy clustering and fuzzy‐based evolutionary technique. The idea is to use FCM for the cluster creation and then selecting the best node as a CH within each cluster formed, by using an evolutionary technique DE. For the CH selection, the fitness of each node is calculated through a designed fuzzy inference system. The simulation results validate the energy‐efficient performance of EEFCM‐DE in comparison with the other existing algorithms.
Band pass filter and AFVmean‐based unintentional islanding detection
Authors: Murugesan Suman , Murali Venkatakirthiga
Published: February 2019

Several international standards have suggested to detect the unintentional island formation to safeguard the working personnel and protect the electrical equipment in the system. An active islanding detection technique, which employs the q‐axis current disturbance injection, has been utilised and an analysing technique is proposed in this work based on a combination of band pass filter and mean of absolute frequency variation (AFVmean) to detect and differentiate the island formation from other transient events. The proposed analysing technique (PAT) detects island formation within 180 ms, which is less than the prescribed time of various international standards, applicable to dynamic loading conditions without the need of adaptive threshold and communication, and offers zero non‐detection zone (NDZ). The disturbance injection makes significant variation in the frequency of voltage signal on post‐islanding condition even for zero‐power mismatch condition, therefore, the NDZ is zero. The PAT is corroborated for various islanding and non‐islanding events and the simulations are performed in MATLAB/Simulink tool.
PCSMC design of permanent magnetic synchronous generator for maximum power point tracking
Authors: Yang Bo , Zhong Linen , Yu Tao , Shu Hongchun , Cao Pulin , An Na , Sang Yiyan , Jiang Lin
Published: February 2019

This study develops a perturbation compensation based sliding‐mode control (PCSMC) strategy of a permanent magnetic synchronous generator (PMSG) for optimal extraction of wind energy. Firstly, PMSG non‐linearities, uncertain parameters, unmodelled dynamics, and stochastic wind speed variations are aggregated into a perturbation. Then, it is estimated by a sliding‐mode state and perturbation observer in the real time. Further, the perturbation estimate is fully cancelled by sliding‐mode controller (SMC) for global control consistency, together with considerable robustness thanks to the sliding‐mode mechanism. In addition, the upper bound of perturbation is replaced by its real‐time estimate; thus more proper control costs could be achieved without over‐conservativeness. Moreover, PCSMC does not require an accurate PMSG model while only the measurement of d‐axis current and mechanical rotation speed is required. Four case studies are carried out, e.g. step change of wind speed, low‐turbulence stochastic wind speed, high‐turbulence stochastic wind speed, and PMSG parameter uncertainties. Simulation results demonstrate that PCSMC can rapidly extract higher power under different wind speed profiles against vector control and SMC. Lastly, a dSpace‐based hardware‐in‐the‐loop experiment is undertaken which validates its implementation feasibility.
Market bidding strategy of the microgrids considering demand response and energy storage potential flexibilities
Authors: Nezamabadi Hossein , Vahidinasab Vahid
Published: February 2019

Volatile impact of intermittent renewable energy sources (RESs) on the one hand and the uncertainties of loads and market prices, on the other hand, make the bidding strategy of microgrids (MGs) too risky and high‐computational problem. To cope with these challenges, the bidding problem of MGs based on a three‐stage hybrid stochastic/interval optimisation (HSIO) is devised in this study, which provides a trade‐off between covering the volatilities by means of the MG potential flexibilities resources or by means of the energy provision from the real‐time market (RTM). To tackle the uncertainties of the day‐ahead market prices, the cost‐effective stochastic programming (SP) is applied to maximise the profit of MG in the day‐ahead stage of decision‐making. In order to handle the volatilities of RESs production and uncertainties of RTM prices, a flexibility scheme based on the robust and low‐computational interval optimisation (IO) approach is designed to minimise the balancing cost of MG in the real‐time stages. Comprehensive numerical results are provided to compare the effectiveness, robustness, and computational complexity of the proposed model. Results show that the HSIO model takes advantage of the cost‐effective solution from the SP model, and the robust solution with computational simplicity from the IO model.
Radiation from quasi‐TEM insulated transmission lines
Authors: Ianconescu Reuven , Vulfin Vladimir
Published: February 2019

We develop here a radiation losses model for quasi‐TEM two‐conductors transmission lines insulated in a dielectric material. The analysis is based on the Maxwell equations and is exact in the quasi‐TEM regime, which is satisfied by the condition of small electric cross‐section. All the analytic results are validated by comparison with ANSYS‐HFSS simulation results and previous published works.
Half‐mode dielectric waveguide antenna fed by a micro‐strip line with air media for endfire radiation
Authors: Hou Yuefeng , Li Yue , Zhang Zhijun , Feng Zhenghe
Published: February 2019

A half‐mode dielectric waveguide antenna fed by a micro‐strip line with air media is presented. The proposed antenna consists of two dielectric cuboids and an air‐substrate micro‐strip line. Due to similar modal field configurations, the dielectric cuboids are excited effectively by the micro‐strip line, and they work as two half‐mode waveguide antennas working on the TM0 mode. With the length of 6.5 wavelength at the centre frequency of 5 GHz, a measured endfire gain of 12.2 dBi is achieved. The measured 1 and 3‐dB gain bandwidths could reach 17 and 46%, respectively. Good matching is obtained over the entire operating band from 3.5 to 6.5 GHz. Compared with the antennas mounted on a large conducting plane, the proposed antenna has the advantages of a high endfire gain, a wide endfire gain bandwidth, and a stable endfire radiation pattern.
Designs of deformed eight‐way Butler matrix with port reduction for massive array beamforming
Authors: Su Yu‐Sheng , Chang Chia‐Chan
Published: February 2019

Massive‐MIMO technology has been proposed for 5G systems, in which beamforming is one of the essential features. In this work, folding deformation technique is proposed to reduce the size of the Butler matrix (BM) used in array system. Based on the mirror symmetry of the conventional BMs, partial components can be saved. By embedding some switches from the feeding network into the internal BMs, the number of building blocks and input ports is decreased. For demonstration, both 4 × 8 BMs and 2 × 8 BMs deformed from a conventional 8 × 8 BM are designed and implemented in this work. Up to 25% reduction in size is achieved when compared to a conventional 8 × 8 BM. The proposed BMs not only can generate eight orthogonal beams, but also can perform the beam synthesis, showing a great potential for future communication systems.
Jamming: The probable menace to NavIC
Authors: Lineswala Priyanka L. , Shah Shweta N.
Published: February 2019

The impact of class‐II jammer on NavIC receiver in L5 band is presented here. To understand the probable hazards of jammer, five cases cum observational studies are reconnoitred using different statistical time and frequency domain approaches. Interestingly, it is noticed that the Carrier‐to‐Noise Density Ratio (C/N0) tends to zero when jamming scenario exist for a longer duration. The effect on NavIC is observed more for the static jammer than the dynamic jammer. The comparisons of correlation for different cases also validate the impact of jammer. The impact of jamming is also identified by different descriptive statistical parameters of the signals like mean, variance, standard deviation, and skewness. Among these statistical analyses, values of mean provide better observation.
The search for radio emission from exoplanets using LOFAR beam-formed observations: Jupiter as an exoplanet
Authors: Turner Jake D. , Grießmeier Jean-Mathias , Zarka Philippe , Vasylieva Iaroslavna
Published: February 2019

Context.The magnetized solar system planets are strong radio emitters and theoretical studies suggest that the radio emission from nearby exoplanets in close-in orbits could reach intensity levels 103–107times higher than Jupiter’s decametric emission. Detection of exoplanets in the radio domain would open up a brand new field of research, however, currently there are no confirmed detections at radio frequencies.

Aims.We investigate the radio emission from Jupiter, scaled such that it mimics emission coming from an exoplanet, with low-frequency beam-formed observations using LOFAR. The goals are to define a set of observables that can be used as a guideline in the search for exoplanetary radio emission and to measure effectively the sensitivity limit for LOFAR beam-formed observations.

Methods.We observe “Jupiter as an exoplanet” by dividing a LOFAR observation of Jupiter by a down-scaling factor and adding this observation to beam-formed data of the “sky background”. Then we run this artificial dataset through our total intensity (Stokes-I) and circular polarization (Stokes-V) processing and post-processing pipelines and determine up to which down-scaling factor Jupiter is still detected in the dataset.

Results.We find that exoplanetary radio bursts can be detected at 5 pc if the circularly polarized flux is 105times stronger than the typical level of Jupiter’s radio bursts during active emission events (~4 × 105Jy). Equivalently, circularly polarized radio bursts can be detected up to a distance of 20 pc (encompassing the known exoplanets 55 Cnc, Tau Boötis, and Upsilon Andromedae) assuming the level of emission is 105times stronger than the peak flux of Jupiter’s decametric burst emission (~6 × 106Jy).
Gravitational waves from post-merger radially oscillating millisecond pulsars
Authors: Dai Z. G.
Published: February 2019

Observations of short-duration gamma-ray bursts and their afterglows show that a good fraction (perhaps ≳50%) of binary neutron star mergers lead to strongly magnetized, rapidly rotating pulsars (including millisecond magnetars), no matter whether the pulsar remnants are short- or long-lived. Such compact objects are very likely to have significant radial oscillations and high interior temperatures, as indicated in recent numerical simulations. In this paper, we have investigated rotation-induced gravitational radiation from possibly existing, radially oscillating pulsars after binary neutron star mergers, and find that this mechanism can efficiently damp the radial oscillations. The resulting gravitational waves (GWs) could have a non-negligible contribution to the high-frequency spectrum. We provide an order-of-magnitude estimate of the event rate and suggest that such GW events would be detectable with the advanced LIGO/Virgo or next-generation detectors. Our discussion can also be applied to newborn, radially oscillating, millisecond pulsars formed through the other astrophysical processes.
Combustion of coal water slurry-technology enabling the achievement of a reduced technical minimum of the boiler
Authors: Głód Krzysztof , Lasek Janusz , Słowik Krzysztof , Zuwała Jarosław
Published: February 2019

The idea of combustion of suspended fuels was developed in the 1980s. The largest producer and user of slurry fuels (Coal Water Slurry, CWS) is China [3]. Despite of several decades of CWS research history, investigations are still carried out to improve the parameters of disperse fuels and to improve the combustion of these fuels. The close relationship between the properties of slurry fuels and number of parameters (mainly the type and properties of the coal feedstock) generates the necessity of CWS receipts and determines for what purposes the fuel may be destined. In the case of the use of coal sludge, the resulting slurry allows for the combustion / "disposal" of coal slurry in pulverized boilers. In the case of using better quality fine coal fractions in CWS production, a slurry will be created allowing for achieving the crucial technological goal such as operation of power units with a reduced technical minimum.
Numerical investigation using two different CFD codes of pulverized-coal combustion process characteristic in an industrial power plant boiler
Authors: Madejski Paweł , Modliński Norbert
Published: February 2019

Steam boilers using the coal as a basic fuel are still one of the most important techniques used to generate electricity in Power Plants. Many activities connected with optimization of steam boilers operation, investigation of combustion efficiency using different fuels, control and reducing pollutants emission are observed. Numerical modeling of large steam boilers using Computational Fluid Dynamic method can be a very way to develop and verify effects of all activities regarding combustion process optimization. Numerical modeling results of the coal combustion process in the front wall coal-fired boiler are presented in the paper. The behavior of the flow of pulverized coal through the burners was analyzed, and the temperature and velocity distribution in the combustion chamber were reproduced in the simulation. Despite the fact that the attention has been focused on boiler simulation at nominal load, it is possible to perform numerical studies concerning the analysis of coal combustion at different boiler loads (minimum load and flexible boiler operation). Analysis of different fuels and their impact on the combustion process, as well as analysis of coal mills operation, coal particles size distribution and they impact on boiler operation can be performed using developed models.
Ammonia desorption from fly ash
Authors: Maj Izabella , Kalisz Sylwester , Gądek Waldemar
Published: February 2019

The main source of ammonia in ash are residues from an unreacted NH3 from the denitrification process, either from SCR or SNCR systems. The paper discusses the standards of NH3 content in fly ash and presents the most commonly used methods of removing excess ammonia from fly ash. In the next part of the work the results of laboratory tests on NH3 desorption are presented. Desorption was performed on samples of fly ash taken from the electrostatic precipitator of real PC boiler. Removal of NH3 from the ash was carried out in a heating chamber at 130°C and 150°C and detected by an analyser equipped with a NDIR sensor. Additionally, at the temperature of 130°C, the NDIR and analytical methods were compared (in accordance with the BN-750541-05 procedure) and the measurement uncertainty of both methods was estimated.
Cross-camera tracking and frequency analysis of a cheap Slinky Wilberforce pendulum
Authors: Devaux Pierre , Piau Valentin , Vignaud Ombeline , Grosse Guillaume , Olarte Renato , Nuttin Alexis
Published: February 2019

A Wilberforce pendulum is a mechanical oscillator often used as an example for the effect of coupling. After establishing a theoretical model of this oscillator and building a prototype, tracking algorithms have been developed to get the position of the oscillator. These tools enable us to highlight the existence of normal modes and determine the constants of the system. We also test different initial conditions to project the state of the pendulum on the normal modes. At the end, we discuss the match between our model and the experimental results. This comparison leads to possible improvements of the model and of the measurements.
Correlation between photoelectrochemical and photoluminescence measurements of Ag-doped ZnO/ITO photoanode
Authors: Dridi Donia , Litaiem Yousra , Karyaoui Mokhtar , Chtourou Radhouane
Published: February 2019

Silver-doped zinc oxide (SZO) thin films have been deposited onto indium-doped tin oxide substrates (ITO) using sol–gel spin-coating technique with different Ag doping content (1, 2 and 5% Ag). The effect of silver incorporation on structural, morphological, optical and photoelectrochemical (PEC) properties of the SZO films was investigated. Ag incorporation resulted in an enhanced grain size and thickness of elaborated SZO films. Scanning electron micrographs exhibited a uniform distribution of spherical grains with particle size increment after doping. Band gap energies were found to increase after Ag doping. Photoluminescence (PL) measurements revealed that the energy band gaps of the films were in the UV region. As compared to pure ZnO thin film, the samples are more photoactive, and the film containing 2% Ag yielded the highest photocurrent. A correlation study between PEC and PL measurements of Ag-doped ZnO/ITO photoanode leads to a reverse variation. Charge transfer processes at the ZnO–electrolyte interface were identified by electrochemical impedance spectroscopy.
η meson physics with WASA-at-COSY
Authors: Hüsken Nils , Demmich Kay , Khoukaz Alfons
Published: February 2019

In recent years, the η meson has been a focal point of research for the WASA experiment at the Cooler Synchrotron COSY of the Research Center Jülich. Production experiments using nucleon-nucleon and nucleon-nucleus collisions have been performed, studying the η − N interaction in various configurations. A better understanding of this interaction is a key aspect in the ongoing search for η-nuclear bound states. In addition, the η meson itself represents an ideal laboratory for precision studies of the strong and electromagnetic interactions as well as for searches for beyond Standard Model physics. Large datasets were assembled using the WASA experiment to enable studies on rare and forbidden decay modes. An overview over recent highlights of the WASA η meson physics programme was given.
The role of mesons in muon g − 2
Authors: Jegerlehner Fred
Published: February 2019

The muon anomaly aμ=(gμ-2)/2 showing a persisting 3 to 4 σ deviation between the SM prediction and the experiment is one of the most promising signals for physics beyond the SM. As is well known, the hadronic uncertainties are limiting the accuracy of the Standard Model prediction. Therefore a big effort is going on to improve the evaluations of hadronic effects in order to keep up with the 4-fold improved precision expected from the new Fermilab measurement in the near future. A novel complementary type experiment planned at J-PARC in Japan, operating with ultra cold muons, is expected to be able to achieve the same accuracy but with completely different systematics. So exciting times in searching for New Physics are under way. I discuss the role of meson physics in calculations of the hadronic part of the muon g-2. The improvement is expected to substantiate the present deviation $\Delta a_\mu ^{{\rm{New}}\,{\rm{physics}}} = \Delta a_\mu ^{{\rm{Experiment}}} - \Delta a_\mu ^{{\rm{Standard Model}}}$ to a 6 to 10 standard deviation effect, provided hadronic uncertainties can be reduce by a factor two. This concerns the hadronic vacuum polarization as well as the hadronic light-by-light scattering contributions, both to a large extent determined by the low lying meson spectrum. Better meson production data and progress in modeling meson form factors could greatly help to improve the precision and reliability of the SM prediction of aμ and thereby provide more information on what is missing in the SM.
Theoretical analysis of the γγ(*) → π0η process
Authors: Deineka Oleksandra , Danilkin Igor , Vanderhaeghen Marc
Published: February 2019

The theoretical analysis of the γγ → π0η process is presented within the energy range up to 1.4 GeV. The S -wave resonance a0(980) is described involving the coupled channel dispersive framework and the D-wave a2(1320) is approximated as a Breit-Wigner resonance. For the a0(980) the pole is found on the IV Riemann sheet resulting in a two-photon decay width of Γa0 → γγ = 0.27(4) keV. The first dispersive prediction is provided for the single-virtual γγ*(Q2) → π0η process in the spacelike region up to Q2 = 1 GeV2.
Pion assisted dibaryons: the d*(2380) resonance
Authors: Gal Avraham
Published: February 2019

The structure and width of the recently established d*(2380) resonance are discussed, confronting the consequences of a Pion Assisted Dibaryons hadronic model with those of quark motivated calculations. In particular, the small width $\Gamma_{d\ast}\approx70$ MeV favors hadronic structure for the d*(2380) dibaryon rather than a six-quark structure.
Kaonic deuterium from realistic antikaon-nucleon interaction
Authors: Horiuchi Wataru , Hyodo Tetsuo , Weise Wolfram
Published: February 2019

We present precise three-body calculations for the spectrum of kaonic deuterium with a realistic antikaon-nucleon interaction. Thanks to the precise measurement of kaonic hydrogen, it is now possible to construct realistic $\bar KN$ interactions which reproduce the whole set of experimental data in the threshold region. Employing such realistic interactions, the energy of the three-body system of kaonic deuterium is determined with the accuracy of eV, by expanding its wave function with a large number of correlated Gaussian basis functions. The level shift and width of the 1S state are found to be 670 eV and 1016 eV, respectively. The improved Deser formulas work reasonably well to estimate the shift and width of kaonic hydrogen, but their application to kaonic deuterium does not give an accurate estimation. It is shown that the result is sensitive to the I = 1 component of the $\bar KN$ interaction, which will be further constrained in future experiments.
XYZ states at LHCb
Authors: Kucharczyk Marcin
Published: February 2019

The latest years have observed a resurrection of interest in searches for exotic states motivated by precision spectroscopy studies of beauty and charm hadrons providing the observation of several exotic states. The latest results on spectroscopy of exotic hadrons are reviewed, using the proton-proton collision data collected by the LHCb experiment. The document focuses among others on the confirmation of the resonant nature of the Z(4430) mesonic state and observation of $J/\Psi \phi $ structures consistent with exotic states. LHCb has also made significant contributions to the determination of the quantum numbers of the X(3872) state and excluded the existence of the X(5568) tetraquark candidate.
Celestial calendar-paintings and culture-based digital storytelling: cross-cultural, interdisciplinary, STEM/STEAM resources for authentic astronomy education engagement
Authors: Lee Annette S. , Wilson William , Tibbetts Jeff , Gawboy Cark , Meyer Anne , Buck Wilfred , Knutson-Kolodzne Jim , Pantalony David
Published: February 2019

In D(L)akota star knowledge, the Sun is known as Wi and the Moon is Han-Wi. They have an important relationship, husband and wife. The pattern of their ever-changing relationship is mirrored in the motions of Sun and Moon as seen from our backyards, also called the lunar phases. The framework of the cultural teaching is storytelling and relationships. Cultural perspectives in astronomy such as this remind us of how indigenous ways of knowing are rooted in inclusion, engagement, and relevancy. Designed by A. Lee in 2007, the Native Skywatchers initiative seeks to remember and revitalize indigenous star and earth knowledge, promoting the native voice as the lead voice. The overarching goal of Native Skywatchers is to communicate the knowledge that indigenous people traditionally practiced a sustainable way of living and sustainable engineering through a living and participatory relationship with the above and below, sky and earth. In 2012 two indigenous star maps were created: the Ojibwe Giizhig Anung Masinaaigan-Ojibwe Sky Star Map (A. Lee, W. Wilson, C. Gawboy), and the D(L)akota star map, Makoce Wicanhpi Wowapi (A. Lee, J. Rock). In 2016, a collaboration with W. Buck of the Manitoba First Nations Resource Centre (MFNRC), produced a third star map: Ininew Achakos Masinikan- Cree Star Map Book. We aim to improve current inequities in education for native young people especially through STEM engagement, to inspire increased cultural pride, and promote community wellness. Presented here will be recently created resources such as: astronomical calendar-paintings and short videos that exist at the intersection of art-science-culture. As we look for sustainable ways to widen participation in STEM, particularly in astronomy education, part of the conversation needs to consider the place for art and culture in STEM.
Evolving from xSonify: a new digital platform for sonorization
Authors: Garcia Beatriz , Diaz-Merced Wanda , Casado Johanna , Cancio Angel
Published: February 2019

In general, Space Sciences data exploration is thought to be suitable for people who do not have Neurological Disorders (ND) that may impair reading (RI), and are not blind or visually impaired (BVI). Data exploration methods used in these fields are generally visual, and do not provide the accessibility to allow full participation of blind and visually impaired individuals in the field. This has been the case even after evidence that sound increases the sensitivity to events in data that would otherwise be undetected. A set of tools that guarantees a thorough data inspection, and assures the access to the same amount and quality of information to all, is useful for everyone.

The present project, devoted to design a new user centered software to produce audio-visual outputs from astrophysical data, integrates multidisciplinary and interdisciplinary astronomers, engineers, computer specialists, software designers, educators, disability specialists, bioengineers, neurobiologists, and sociologists, both blind and sighted, and addresses the topics of accessibility to astronomical data, The possibility of exploring the bibliographic databases (ADSABS, among others), creation of a new multimodal access prototype, creation of an accessible, user-centered (from back end to front end), human-computer interface suitable for collection, sonification and analysis of astrophysical data, and the efficiency, utility and effectiveness of the resource in different cultural environments and at different levels of expertise. In this contribution, we present the first results related to the creation and application of the techniques and tools proposed, taking into account that the focus of this research is on the knowledge in the field of physics and astrophysics, but can be scalable to other areas of human activity so that people with other learning styles can have "equal opportunities". Finally, this project is based on the premises of addressing the technical challenges in basic research to achieve the promised benefits of Big Data, which is of world-wide interest.
Optical Polarimetry in Undergraduate Education
Authors: Topasna Gregory
Published: February 2019

Polarimetry plays an important part in observational astronomy, but it is all too often given limited attention in astronomy textbooks. Coupled with a sometimes confusing mathematical introduction, students may feel that polarization is a difficult subject best left for study at a different time, or worse, not at all. Additionally, polarimetric observations and analysis are not typical exercises students are likely to engage in as part of an observational astronomy course. Over the past few years students at Virginia Military Institute have used an optical polarimeter, which was designed and constructed in-house, on the 20 cm Cassegrain telescope at the VMI Observatory to study the polarization of stars. These observations have enhanced their astronomical knowledge and allowed them the opportunity to gain valuable experience using this important technique. The subsequent analysis of stellar polarization has led to a better understanding of the mathematics of polarization, its interpretation, and statistical treatment. In this paper I describe the design and construction of an optical polarimeter suitable for a small college observatory and outline the observing and data analysis strategies. I will also present observations that range from brief introduction exercises that can be included as part of an observational astronomy course to longer programs suitable for undergraduate research projects.
Teaching conceptions on the use of digital technologies as a teaching resource in physical education in public schools of Minas Gerais, Brazil
Authors: Voelzke Marcos Rincon , Paganotti Arilson , Maia Marcossi Assis Adriana
Published: February 2019

It is observed that the technologies have invaded the classrooms, providing increasingly attractive teaching methods. Technologies have challenged school institutions to keep up with this new reality. In some cases, the technologies offered aim, to a certain extent, to meet some educational needs of students and soften deficiencies in classroom teaching. The arrival of digital technologies in classrooms brings great advances, but also brings many uncertainties and insecurities, giving rise to new tensions, new possibilities and new challenges. With today's technologies, the school environment can transform into a meaningful, face-to-face and digital learning environment, making students more active, motivating them to learn and search all the time. The present work aims to present the advantages and disadvantages of these digital methods, as well as to demonstrate the applicability of these technologies in the current daily life of school institutions. It also presents some important aspects about the use of technologies in the learning process, discussing how the use of virtual simulations software can contribute to the teaching of Physics. To obtain data from the students, a questionnaire with seven questions was used.
Astronomy across cultures: reporting experiences on the GalileoMobile education activities in the Paiter Suruí indigenous community
Authors: Figueiró Spinelli Patrícia , Germano Ana Paula , Germano Ana Paula , Fernades Cristina , Benitez-Herrera Sandra , Carrelli Sá Silva Felipe ,   Galileo Mobile team
Published: February 2019

This work is the report of an astronomy non-formal education expedition carried out by the GalileoMobile initiative in the Paiter Suruí indigenous communities, in the Brazilian Amazon, that took place in November 2016. This ethnic group remained “officially uncontacted” by non-natives until the late 1960's, when the population dropped significantly and they faced deep changes in their way of living and traditions. Nowadays, the Paiter Suruí are seeking ways to maintain their cultural identity and land. Thus, differently from previous GalileoMobile itinerant projects, which had the goal of bringing modern astronomy closer to youngsters of regions with scarce access to science outreach actions, this particular expedition had the goal of establishing an exchange of knowledge related to astronomy, promoting a dialogue with the members of this group to understand and record their relationship with the sky. The ground team, comprised of three astronomers, one filmmaker and one anthropologist, undertook the study of various academic works on ethno and cultural astronomy, as well as specific texts on science education in traditional communities and ethnography of Brazilian indigenous peoples. During the expedition, interviews with the Paiter Suruí elders were held, having as a starting point astronomy outreach activities such as the sky observation with telescopes. We were able to collect three myths related to the Sun, Moon and rainbow. The result of activities, interviews and transcripts were recorded in a series of videos that will be returned to the community, so that they can be used in schools and community centres as educational material for the preservation of the Paiter Suruí culture, as well as a resource for a detailed ethnographic study of their astronomy.
Analysing Big Social Graphs Using a List-based Graph Folding Algorithm
Authors: Muntyan Eugenia , Sergeev Nikolay , Tselykh Alexey
Published: February 2019

In this paper, we explore the ways to represent big social graphs using adjacency lists and edge lists. Furthermore, we describe a list-based algorithm for graph folding that makes possible to analyze conditionally infinite social graphs on resource constrained mobile devices. The steps of the algorithm are (a) to partition, in a certain way, the graph into clusters of different levels, (b) to represent each cluster of the graph as an edge list, and (c) to absorb the current cluster by the cluster of the next level. The proposed algorithm is illustrated by the example of a sparse social graph.
Design and Implementation of Welding Robot Based on PLC
Authors: Wang Litao
Published: February 2019

With the development of the revolutionary tide of new technology, our production scale is gradually expanding. Manual production has been unable to meet the requirements of industrial production. In order to improve production efficiency and welding quality, we developed a welding robot. Because it has the characteristics of high production efficiency, stable welding quality and large practical demand. It is developing most rapidly. With the development of PLC technology, we gradually apply it to the development of welding robot. Its advantages of good ductility, low cost and convenient maintenance can bring great value to industrial production.
Quand les recherches en sciences sociales s’invitent dans la gestion de l’eau
Authors: Barataud Fabienne , Hellec Florence , Levain Alix , Petit Sandrine
Published: February 2019

La gestion de la qualité de l’eau est soumise à deux injonctions : un impératif scientifique et un impératif participatif. Au travers de notre expérience de chercheuses en sciences sociales engagées dans quatre démarches de protection associant des projets de recherche souvent pluridisciplinaires, cet article propose un retour réflexif sur les attentes exprimées par rapport à notre participation, ainsi que sur l’évolution de notre positionnement. Il apparaît alors que la place des chercheurs en sciences sociales n’est jamais totalement acquise, parce qu’elle produit des connaissances essentiellement dialogiques, dont les objets se déplacent et se transforment au fil des enquêtes et des interactions avec les porteurs d’enjeux. C’est finalement moins par l’intervention directe que par la réorientation de nos questions de recherche vers des problématiques liées à ces enjeux que nous avons pu partiellement contribuer aux dispositifs de gestion des pollutions diffuses d’origine agricole.
Periodontal approach of impacted and retained maxillary anterior teeth
Authors: Henner N. , Pignoly M. , Antezack A. , Monnet-Corti V.
Published: February 2019

Treatment of the impacted and retained teeth is a multidisciplinary approach involving close cooperation between periodontist and orthodontist.

Clinical and radiographic examination leading subsequently to diagnosis, remain the most important prerequisites permitting appropriate treatment.

Several surgical techniques are available to uncover impacted/retained tooth according to their position within the osseous and dental environment.

Moreover, to access to the tooth and to bond an orthodontic anchorage, the surgical techniques used during the surgical exposure must preserve the periodontium integrity. These surgical techniques are based on tissue manipulations derived from periodontal plastic surgery, permitting to establish and maintain long-term periodontal health.
The Prevalence of Musculoskeletal Disorders and Work-Station Evaluation in Bank Employees
Authors: Umar Aneela , Kashif Muhammad , Zahid Nawal , Sohail Ramsha , Arsh Aatik , Raqib Abdul , Zada Pir
Published: February 2019

Objective The objective of the study was to evaluate the computer workstation settings and the prevalence of musculoskeletal (MSK) related problems in computer users of bank.

Methods A cross-sectional study was conducted among100 computer users of State Bank of Pakistan, Faisalabad and National Bank of Pakistan, Faisalabad from March to December 2017. Inclusion criteria of the study were male and female bank workers, age between 25–60 years who use desktop computers for at least 3 h a day and had at least 6 months working experience. Cornell Musculoskeletal Discomfort Questionnaire (CMDQ) was used to determine prevalence of MSK problems while Rapid Office Strain Assessment (ROSA) tool was used to evaluate Computer Work-Station (CWS) ergonomic parameters. The data was analyzed by descriptive statistics and variant correlation using SPSS version 20.

Results The mean CMDQ was higher (43.0 ±33.6) in female than male (16.9±20.8) and there was significant association between gender and total discomfort (P=0.001). The discomfort was higher among females then males. The body parts reported to have the most significant levels of discomfort was the neck and head (mean 3.595±7.49), lower back (2.75±5.39) and right shoulder (mean 2.15±4.32).

About 40% subjects suffered from neck pain while the remaining body parts having discomfort were right shoulder (39%), left shoulder (37%), and low back (36%).Almost 90% of the participants had ROSA score greater than 5 that shows that most individuals were at higher risk of ergonomics hazardous.

Conclusion The results of the present study demonstrated that MSK discomfort is common among computer users of bank employees and neck, shoulder and lower back region were at greater risk. MSK discomfort was higher in females. Workers are exposed to ergonomic hazards and need immediate improvement.
Facile Total Synthesis of Thailandepsins D–F: Novel Bicyclic Depsipeptide Histone Deacetylase Inhibitors Isolated from a Microorganism
Authors: Katoh Tadashi , Sayar Noel , Narita Koichi
Published: February 2019

The naturally occurring bicyclic depsipeptide histone deacetylase inhibitors thailandepsins D–F were efficiently synthesized for the first time in 49–61% overall yield over five steps, starting from known amine and carboxylic acid segments. The synthesis includes the condensation of the two known starting materials to directly assemble the corresponding seco-acids, which are the key precursors for macrolactonization. The seco-acids are then macrolactonized using the Shiina method to construct the requisite 15-member macrocycles.
A New Total Knee Arthroplasty Design Has Significantly Better Early Implant Survivorship than a Previous Gold-Standard Design—A Retrospective Analysis of 1,000 Cases
Authors: Bloch Benjamin V. , Palan Jeya , Shahid Mohammad , James Peter J.
Published: February 2019

This study examined whether a new total knee arthroplasty (TKA) prosthesis improved implant survivorship and reoperation rates compared with a gold-standard, established TKA. A retrospective analysis of the first 500 consecutive new TKAs was compared with a consecutive series of the last 500 currently available TKAs performed by a single senior surgeon in one center. The primary outcome measure was revision of the femoral, tibial, or patellar component. A secondary outcome was reoperation for any reason. The new-TKA group had a significantly reduced revision rate at up to 5 years follow-up (p = 0.02). Reoperation rates for any reason were similar (p = 0.3). The new TKA design has a significantly better early revision rate compared with a currently available gold-standard TKA. This is the largest study of 1,000 cases comparing a new TKA design with a currently available design with excellent midterm results. It demonstrates very favorable early clinical results for the new TKA design, providing reassurance for patients, surgeons, and regulatory bodies.
4 Flow Photochemistry in Organic Synthesis
Authors: Telmesani R. , Sun A. C. , Beeler A. B. , Stephenson C. R. J.
Published: February 2019

Performing photochemical reactions in flow has helped increase their efficiency, scalability, and utility. These efforts have brought photochemistry back to prominence as a powerful tool for synthesis. This chapter outlines the most important procedures and flow setups that can be used to perform photochemical transformations. Examples include ultraviolet-light-driven photocycloadditions and reactions with reagents such as singlet oxygen and transition-metal catalysts. Applications of visible-light photoredox catalysis in continuous-flow systems are discussed in the context of late-stage fluorination, natural product synthesis, alkyl–aryl cross coupling, and lignin fragmentation.