bluuebunny/crossref_metadata_2025 huggingface dataset:
Bird Measurements - ISL Peru v1
Authors: Luis Mendoza-Silva Jorge
Published: September 2023

This protocol describes how to collect the relevant measurements during bird processing.
The Duration of the Cycle to Get the P Amplitude on A Discrete Electrocardiogram
Authors: Setiawidayat Sabar
Published: September 2023

The P amplitude value for each cycle has not been carried out even though it is related to indications of atrial hypertrophy. The basic interpretation of the maximum P amplitude under normal conditions is 2.5 small squares on electrocardiogram (ECG) paper which is equivalent to 2.5 mV. Apart from these interpretations, an amplitude value is required that corresponds to the amount of depolarization of the atrial muscle cells. The difficulty faced by researchers is the lack of discrete ecg data available for experiments, so it only depends on amplitude data as a function of Physionet output time. An ECG is produced using discrete data but there is no electrocardiograph that displays discrete data yet. This study aims to obtain the P amplitude value based on discrete electrocardiogram data. The cycle duration value obtained from R to R is used to obtain the initial position of the cycle (sc) with the formula RN+1-1.5dR for each cycle. The P amplitude value can be obtained by filtering the maximum amplitude value between the sc and RN positions. The results of research on 10 physionet samples and 10 RSSA samples showed that all samples had an amplitude R, cycle duration and P amplitude value in each cycle.
Leveraging Smart Technology for User Experience Personalization – A Comparative Case Study of Innovative Payment Systems
Authors:   National Chengchi University, Shang Shari S.C. , Chiu Lynn S. L. ,   National Chengchi University
Published: September 2023

Background: This study seeks to understand how the attributes of smart technology (SMT) can be leveraged to enable personalized services and optimize unique user experiences to attract and retain customers. Based on Kang et al.’s (2020) study of SMT attributes and quality effects and Liang et al.’s (2006) study on personalized recommendation and user satisfaction, we constructed a SMT personalization model to analyze how the SMT attributes of smart functionality and smart content enable personalization in different ways and create unique customer experiences throughout the user journey. Method: Two representative payment systems were selected to depict how they integrated the strengths of personalized smart functionalities and contents to innovate their business models, optimize user experiences, and sustain business growth. Results: Based on the comparative analysis of the two payment cases, the functionality and content attributes of smart chips and omni-channel platforms were explored, and the tailored advisory and responsive support for customers both offline and online were validated. Conclusion: The life-enriching service innovations provide valuable insights for leveraging SMT for personalization. It is hoped that the SMT personalization model can be extended to other types of SMT applications and can be used as a framework for designing innovative services. Recommended Citation Shang, Shari S.C. and Chiu, Lynn S. L. (2022) "Leveraging Smart Technology for User Experience Personalization – A Comparative Case Study of Innovative Payment Systems," Pacific Asia Journal of the Association for Information Systems: Vol. 14: Iss. 1, Article 6. DOI: 10.17705/1pais.14106 Available at: https://aisel.aisnet.org/pajais/vol14/iss1/6
What Impacts Backers’ Behavior to Fund Reward-Based Crowdfunding Projects? A Systematic Review Study
Authors:   King Saud University, Alhammad Muna M. , Tan Chekfoung ,   University College London, Alsarhani Noha ,   Bank Albilad, Zolkepli Izzal Asnira ,   University Sains Malaysia
Published: September 2023

Background: With Covid-19 spreading across the world, many economic issues have raised. Effort is continued to support vulnerable individuals and start-ups to survive during this pandemic. Reward-based crowdfunding (RBCF) is seen as alternative sustainable finance in the Fintech industry. It allows fund-seekers to pledge an investment through RBCF platforms such as Kickstarter for funding their projects. Backers will get a reward in return. Research has shown that factors impacting the backers' behavior are crucial in determining the success of RBCF campaigns. However, there is a literature gap in providing a holistic view of these factors. Therefore, this paper aims to review and identify factors impacting backers' behavior by conducting a Systematic Literature Review (SLR). Method: This paper employs the three stages in conducting the SLR. It starts with identifying the review strategy where a search string is developed. A total of 323 papers from 2012 up to 2019 from two main academic databases, i.e. IEEE Xplore and ScienceDirect were retrieved. After applying the quality assessment criteria, 33 papers were qualified for the analysis. Thematic analysis was then applied to thematically categories the identified factors. Results: A large set of factors was identified in the literature. Identified factors were classified under nine main themes. These themes are Team Characteristics, Project Characteristics, Social Influence, User Generated Content, Risk, Distrust, Upfront Marketing, Environment Readiness, and Backers Motivation. Conclusions: This paper contributes theoretically by comprehensively identify factors impacting backers’ behavior toward using RBCF. The findings also contribute empirically, particularly to the fund-seekers, to help them understand what factors might impact the backer’s behavior and enhance their chances of designing a successful campaign.
How to Create Personas: Three Persona Creation Methodologies with Implications for Practical Employment
Authors:   Qatar Computing Research Institute, Jansen Bernard J. , Jung Soon-Gyo ,   Qatar Computing Research Institute, Nielsen Lene ,   IT University of Copenhagen, Guan Kathleen W. ,   University College London, Salminen Joni ,   Qatar Computing Research Institute, Turku School of Economics at the University of Turku, School of Marketing and Communication, University of Vaasa
Published: September 2023

Background: Personas are a technique for enhanced understanding of users and customers to improve the user-centered design of systems and products. Their creation can be categorized using three persona creation methodologies: Qualitative, Quantitative, and Mixed Methods. Despite the apparent differences in these methodologies, no previous review has systemically compared and contrasted the strengths and weaknesses of each of these methodologies for persona development. Method: This manuscript maps and navigates persona literature to identify the benefits and challenges of these three persona creation methodologies. Furthermore, the strategies and opportunities of the different methodologies are presented. Results: The results summarize the strengths and weaknesses of each of the three principal persona creation methodologies and offer suggestions of the benefits of their employment. Conclusion: In conclusion, we offer insights into the construction and usage of personas for practitioners and researchers, and we propose a framework to determine which persona creation methodology is most suitable for a given context. Keywords: Algorithmically-Generated Personas, Persona Analytics, Persona Science.
Privacy and Online Social Networks: A Systematic Literature Review of Concerns, Preservation, and Policies
Authors:   Dakota State University, Mitchell Damion R. , El-Gayar Omar F. ,   Dakota State University
Published: September 2023

Background: Social media usage is one of the most popular online activities, but with it comes privacy concerns due to how personal data are handled by these social networking sites. Prior literature aimed at identifying users’ privacy concerns as well as user behavior associated with privacy mitigation strategies and policies. However, OSN users continue to divulge private information online and privacy remains an issue. Accordingly, this review aims to present extant research on this topic, and to highlight any potential research gaps. Method: The paper presents a systematic literature review for the period 2006 - 2021, in which 33 full papers that explored privacy concerns in online social networks (OSN), users’ behavior associated with privacy preservation strategies and OSN privacy policies were examined. Results: The findings indicate that users are concerned about their identity being stolen, the disclosure of sensitive information by third-party applications and through data leakage and the degree of control users have over their data. Strategies such as encryption, authentication, and privacy settings configuration, can be used to address users’ concerns. Users generally do not leverage privacy settings available to them, or read the privacy policies, but will opt to share information based on the benefits to be derived from OSNs. Conclusion: OSN users have specific privacy concerns due primarily to the inherent way in which personal data are handled. Different preservation strategies are available to be used by OSN users. Policies are provided to inform users, however, these policies at times are difficult to read and understand, but studies show that there is no direct effect on the behavior of OSN users. Further research is needed to elucidate the correlation between the relative effectiveness of different privacy preservation strategies and the privacy concerns exhibited by users. Extending the research to comparatively assess different social media sites could help with better awareness of the true influence of privacy policies on user behavior.
Business Model Evaluation: A Systematic Review of Methods
Authors:   TNO, Strategic Business Analysis, Gilsing Rick ,   Eindhoven University of Technology,, Turetken Oktay ,   Eindhoven University of Technology, Grefen Paul ,   Atos Digital Transformation Consulting; Eindhoven University of Technology, Ozkan Baris ,   Eindhoven University of Technology, Adali Onat Ege ,   ASML; Eindhoven University of Technology
Published: September 2023

Background: As a result of factors such as digitization and rapid technology change, organizations are compelled to innovate their business models at an accelerated pace. While the domain of business model innovation has focused on understanding and structuring the process of innovation, it offers limited guidance for evaluating business models during the innovation process. Business model evaluation plays a vital role in supporting decision-making about the performance or viability of new business models and motivating continued investments. Existing literature on methods for business model evaluation and their application is limited and available information is scattered. Furthermore, as the BMI process covers a broad spectrum of activities - from business model initiation to implementation - the evaluation challenges and the effectiveness of evaluation methods vary across the phases of innovation. Thus, there is a need for a better understanding on methods for business model evaluation, and their timing and application for business model innovation. Method: Through a systematic literature review, we have investigated the methods available for business model evaluation and focused on understanding their characteristics and effective timing of application in the business model innovation process. Results: We have identified six groups of methods used for business model evaluation. Additionally, we find that early phase business model evaluation is predominantly qualitative in nature, whereas late phases of business model innovation are generally supported through quantitatively-oriented methods. Moreover, we observe that limited evaluation support is available in the literature to support the initiation phase of business model innovation. Based on our findings, we propose a guiding structure for aligning the available methods with the respective innovation phases. Conclusion: The proposed guiding structure offers guidance for business model evaluation in practice and serves as a basis for future research in developing more effective methods and tools for business model evaluation and development.
Total neoadjuvant chemotherapy according to the FOLFIRINOX regimen for locally advanced adenocarcinoma of the stomach and cardioesophageal junction: interim results
Authors: Sedova M. V. , Batov M. A. , Kolomeytseva A. A. , Khomyakov V. M. , Volchenko N. N. , Fedenko A. A.
Published: September 2023

Purpose. To study the eﬃcacy and safety of total neoadjuvant chemotherapy (NACT) with the FOLFIRINOX regimen for locally advanced gastric (GC) and cardioesophageal junction (CEJ) cancer.

Patients and methods. Patients with histologically conﬁrmed locally advanced gastric adenocarcinoma and CEJ, clinical stage cT3 or higher and/or regional lymph node involvement (cN+), without evidence of distant metastasis were included in our open-label, single-centre, non-randomised study. In the FLOT control group, patients received 4 courses preoperatively and 4 postoperatively with follow-up. I In the FOLFIRINOX group 8 courses of chemotherapy were administered in neoadjuvant mode, followed by surgery and observation. The tumor regression grade was assessed in accordance with Becker, Mandard and G. A. Lavnikova scales.

Results. The study included 136 patients, 119 of whom started treatment according to the protocol (ITT population). Fiﬅy-nine patients were enrolled into the FLOT group and 60 into the FOLFIRINOX group. One-year progression-free survival (PFS) was 67,5 % in the FLOT group and 90,4 % in the FOLFIRINOX group (p = 0,29). The estimated 2-year PFS in the FLOT group was 61,4 % [95 % CI, 48,4–77,9 %]. Median PFS and overall survival (OS) were not reached. The incidence of events (progression or death) was lower in the FOLFIRINOX group (odds ratio [OR] 0,40 [95 % CI 0,16–0,97, p = 0,047]). Adverse prognostic factors regardless of treatment were lymphatic (L1), vascular (V1) and perineural invasion (Pn1), and regional lymph node involvement aﬅer chemotherapy (ypN+) [p = 0,046; p = 0,014; p = 0,0021; p = 0,04, respectively]. There was no correlation between pathological complete response and survival rates.

Conclusion. Total neoadjuvant chemotherapy with the FOLFIRINOX regimen for locally advanced GC/ CEJ demonstrated comparable to the perioperative FLOT one-year PFS rate. No association was found between tumor regression grade and survival outcomes.
Levels of neurotrophins in the brain of female rats in an experimental model of malignant tumor growth under conditions of hypothyroidism
Authors: Surikova E. I. , Frantsiyants E. M. , Bandovkina V. A. , Kaplieva I. V. , Neskubina I. V. , Pogorelova Yu. A. , Trepitaki L. K. , Cheryarina N. D. , Nemashkalova L. A. , Arakelova A. Yu. , Salatova A. M.
Published: September 2023

Objective. Studying the levels of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF-β), and neurotrophin 3 (NT3) in the cerebral cortex and subcortical substance of female rats in an experimental model of extracerebral growth of malignant tumor under conditions of induced hypothyroidism.

Materials and methods. An experiment was performed on 47 white non-linear female rats: 10 rats each in the intact group, control group 1 (induced hypothyroidism), control group 2 (subcutaneous growth of Guerin’s carcinoma), main group (combination of pathologies); 7 rats in the group with subcutaneous tumor growth to assess life expectancy. Hypothyroidism was induced by per os administration of thiamazole (mercazolil, Akrikhin, Russia), daily dose of 2.5 mg/100 g of body weight, course of 30 days; total thyroxine and thyroid stimulating hormone were determined in blood serum by RIA (Immunotech, Czech Republic). When persistent hypothyroidism was achieved, Guerin’s carcinoma was transplanted under the skin as standard. Aﬅer decapitation on the 18th day aﬅer transplantation, the content of BDNF, NGF-β, NT3 (R&D System, RayBiotech, USA) was determined in 10 % homogenates of the cortex and subcortical substance subcortex of the brain (R&D System, RayBiotech, USA).

Results. In the cortex in control groups 1 and 2, the level of BDNF was 2.6- and 1.6-fold lower, respectively, and NGF-β was 2.2-fold higher on average than in the intact group. NT3 levels in the control group 1 were 3.0- and 1.6-fold lower in the cortex and subcortical substance, respectively. In the control group 2, the levels of NT3 and NGF-β were higher in the subcortical matter than in the intact group by 2.4-fold and 3.1-fold, respectively. In the cortex and subcortical substance in the main group, only NGF-β levels were higher on average by 1.7 times, with values being intermediate between the corresponding values in control groups 1 and 2.

Conclusion. Changes in the levels of all neurotrophins in hypothyroidism were most pronounced in the cortex, while in independent tumor growth, NGF-β in the cortex and subcortical substance and NT3 only in subcortical substance changed the most. When the pathologies were combined, only NGF-β was altered in the cortex and subcortical substance. Apparently, there is an interaction of the tumor and the CNS with changes in the balance of regulatory signals in the subcortical areas of the brain, that reﬂecting the connection with the biological characteristics of an active or inhibited (in presence of hypothyroidism) tumor growth.
The effect of smoking on the immediate effectiveness of induction chemotherapy in the combined treatment of HPV-associated oropharyngeal cancer
Authors: Golubev P. V. , Bolotina L. V. , Gevorkov A. R. , Deshkina T. I.
Published: September 2023

Purpose. Evaluation of the eﬀect of smoking on the immediate eﬀectiveness (achievement of objective response – OR) of induction chemotherapy in patients receiving combined treatment for locally advanced HPV-positive squamous cell carcinoma of the oropharynx.

Patients and methods. Sixty-eight patients (51 men and 17 women) with locally advanced squamous cell cancer of the oropharynx associated with papillomavirus were included in the study, which was carried out from 2021 to 2023 at the P. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre, Ministry of Health of the Russian Federation, Moscow, Russian Federation and the Municipal Clinical Oncological Hospital № 1 of the Department of Health of Moscow. The patients were divided into 2 equal groups, fully comparable in terms of the main characteristics (smoking history, stage, histological type, and degree of tumour diﬀerentiation). At the ﬁrst stage, patients of the 1st (main) group received de-escalated induction chemotherapy: three 21-day courses according to the TR scheme (docetaxel in the dose of 75 mg/m2 + cisplatin 75 mg/m2); patients of the 2nd (control) group were treated with standard scheme (docetaxel 75 mg/m2 + cisplatin 75 mg/m2 + 5-ﬂuorouracil 1000 mg/m2). Patients in both groups received prophylactic granulocyte colony-stimulating factor. At the second stage, standard chemoradiotherapy was carried out against the background of drug radiomodiﬁcation with carboplatin. Correlation analysis was performed by calculating the Spearman coeﬃcient with Bonferroni correction. Diﬀerences were considered reliable at p < 0.05.

Results. When evaluating the objective response to treatment, it was revealed that disease control was achieved in 33 (97 %) patients from group 1 and in all 34 (100 %) patients from group 2. Complete response was observed in 3 (8.8 %) patients from group 1 and 4 (11.8 %) from group 2; partial regression in 22 (64.7 %) and 24 (70.6 %); stabilisation of the tumour process in 8 (23.5 %) and 6 (17.6 %) respectively. Further analysis showed that there was no direct or inverse correlation between smoking and diﬀerentiated level of response (primary lesion, altered lymph nodes); all patients (smokers and those who had never smoked) responded equally eﬀectively to the ﬁrst stage of combined treatment, regardless of the ICT regimen.

Conclusion. In our study, no statistically signiﬁcant eﬀect of smoking on the immediate eﬀectiveness of induction chemotherapy in the combined treatment of locally advanced HPV-associated squamous cell carcinoma of the oropharynx regardless of the induction regimen was found. However, a longer follow-up period is needed to evaluate the eﬀect of smoking on long-term oncological outcomes.
АSSESSMENT OF VERTICAL CHANNEL DEFORMATIONS OF THE ТETEREV BASIN RIVERS
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, OBODOVSKYІ O.G. , KORNIIENKO V.O. ,   Ukrainian hydrometeorological center of the State Emergency Service of Ukraine, KUZMOCHKO V.YU. ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Published: September 2023

The investigation of vertical channel deformations of the main rivers of the Teteriv basin over the last 40 years according to the data of 6 hydrological stations was carried out. The prerequisite for this was the establishment of trends in changes in the water discharge of the considered watercourses. A general decrease of these indicators, especially the average and maximum flow indicators, was revealed. This is confirmed by previously conducted studies on water level fluctuations of the researched rivers. The results proved a universal increase in water levels for the rivers of the basin at fixed water discharge within the river banks. This is evidence that accumulation processes are observed on all explored riverbeds, although their intensity may be manifested in different ways. It is shown that modern vertical channel deformations characterize the accumulation of sediments in the riverbeds of the basin, the average intensity of which varies within 0.27-1.31 cm/year. In general, this trend is confirmed by the change in the longitudinal profiles of the rivers during the specified period, where in the areas where the hydrological stations are located, a slight shift of one relative to the other can be observed, with the prevailing height positions of the longitudinal profile for the year 2020. Comparative analysis of discrete (according to flow curves based on data from hydrological stations) and continuous (according to longitudinal profiles) estimates of vertical channel deformations makes it possible to more objectively establish the trends of their manifestations.
APPEARANCE DATES OF ICE PHENOMENA ON THE DNIPRO CASCADE RESERVOIRS AND THE POSSIBILITY OF THEIR LONG-TERM FORECASTING
Authors:   Ukrainian Hydrometeorological Institute of the National Academy of Sciences of Ukraine and the State Service Emergencies of Ukraine, Kyiv, Khrystiuk B.F. , Gorbachova L.О. ,   Ukrainian Hydrometeorological Institute of the National Academy of Sciences of Ukraine and the State Service Emergencies of Ukraine, Kyiv, Rozlach V.O. ,   Ukrainian Hydrometeorological Institute of the National Academy of Sciences of Ukraine and the State Service Emergencies of Ukraine, Kyiv
Published: September 2023

Long-term forecasting of the appearance dates of ice phenomena on the Dnipro Cascade reservoirs, especially with the forecast lead time at least 1 month, has important practical and scientific significance. So, it is on the basis of this characteristic of the ice regime that the terms and depths of autumn operation of each of the six Dnipro reservoirs are determined. Along with this, there are no methods for long-term forecasting of the appearance date of ice phenomena on the Dnipro Cascade reservoirs. Obviously, this is due to the fact that the problem of developing reliable long-term forecasts of the ice regime of water bodies is one of the most difficult in hydrometeorology, which has not yet received a fully satisfactory solution. The objective of this of the research is to find connections between quantitative indicators of atmospheric processes in the North Atlantic and the appearance dates of ice phenomena on the Dnipro Cascade reservoirs, and to evaluate the possibilities of using the obtained results for operational long-term forecasting. In long-term forecasting of ice regime is used the statistical, correlational, regression analysis as well as the atmospheric indicators as predictors. Therefore, the minimum atmospheric pressure in the center of the Icelandic minimum, the North Atlantic Oscillation (NAO) pattern and the Scandinavian Oscillation (SCAND) pattern were used in the research. These indicators characterize the atmospheric processes of the North Atlantic. Materials of the Department of Meteorological Forecasts of the Ukrainian Hydrometeorological Center (Kyiv) and the National Oceanic & Atmospheric Administration USA (archival synoptic maps, the values of NAO and SCAND patterns) were used as initial data. The obtained results show that such indicators of the atmospheric processes of the North Atlantic as the minimum atmospheric pressure in the center of the Icelandic minimum, NAO and SCAND patterns undoubtedly have a fairly significant influence on the formation of the appearance dates of ice phenomena on the Dnipro Cascade reservoirs, but such an influence is not predominant and such indicators can only be partially used as predictors for long-term forecasting. Therefore, to obtain more acceptable results, it is necessary to expand the search for predictors of atmospheric processes both in space and time.
COMPONENTS OF THE RADIATION REGIME OF SOLAR RADIATION DURING DROUGHTS FOR 1991-2020 IN UKRAINE
Authors:   Ukrainian Hydrometeorological Institute of the National Academy of Sciences of Ukraine and the State Service Emergencies of Ukraine, Rybchenko L.S. , KyivSavchuk S.V. ,   Ukrainian Hydrometeorological Institute of the National Academy of Sciences of Ukraine and the State Service Emergencies of Ukraine
Published: September 2023

Changes in the components of the radiation regime of solar radiation during periods of intense droughts and their comparison with average values for 1991-2020 in Ukraine are given. Drought is a complex and dangerous natural phenomenon caused by the anticyclonic nature of the atmospheric circulation, the long-term transformation of slow-moving air masses over large areas. A complex of dynamic processes leads to its development. They are facilitated by an increased supply of short-wave radiation, high air temperature, a rainless period, and a lack of moisture in the air and soil. The archive of measurements of the meteorological and actinometric network of observations of the Borys Sreznevskiy CGO of the SES of Ukraine was used. A database of observations of individual components of the radiation regime of solar radiation and a catalog of droughts has been created. Droughts of different intensity and duration during the growing seasons for 1991-2020 were determined. The change in atmospheric circulation led to an increase in clear and cloudless weather, changes in the arrival of components of the radiation regime of solar radiation to the substratum. The biggest changes were in the warm period. In 1991-2020, relative to 1961-1990, the duration of sunshine, direct and total solar radiation increased during the year, and diffuse radiation decreased. During 1991-2020, droughts were observed for 22 years, including 17 growing seasons throughout the territory. They differed in types (air, air-ground, ground), duration, distribution. Prerequisites for the development of droughts were observed in some cold periods. In particular, droughts. observed in November, February-March. In the warm period, intense droughts were observed for short periods of time (less than a month) in some areas and powerful, long-lasting ones in the prevailing area. In certain months of the growing season during droughts, significant deviations of individual components of solar radiation compared to the average for 1991-2020 were observed throughout the country. Usually, during dry periods, the duration of sunshine and direct solar radiation increased significantly, diffuse radiation decreased, so the total radiation did not always increase. An increase in individual components of the radiation regime led to an increase in the total radiation balance and albedo of the underlying surface. The research is part of the monitoring of climate anomalies. They are necessary for solving applied problems of adapting agricultural production to permanent and long-term droughts in a large area.
EXAMINING THE MEDIATING ROLE OF ORGANIZATIONAL TRUST ON THE EFFECT OF ETHICAL CLIMATE ON EMPLOYEE VOICE IN THE HEALTH SECTOR
Authors: Bilen Gül , Yıkılmaz İbrahim , Sürücü Lütfi
Published: September 2023

The main purpose of this study is to reveal whether organizational trust plays a mediating role in the effect of ethical climate perception observed in the health sector on employee voice. In the study designed according to the quantitative research method; the data were collected from the health workers working in a private hospital affiliated to the Provincial Health Directorate in the province of Istanbul by convenience sampling method. SPSS 27, AMOS 22 programs and Process Macro plugin were used in the analysis of the data obtained in the study. According to the findings of the research; organizational ethical climate positively and significantly affects employee voice and organizational trust plays a mediating role in this relationship. In the working environment where the organizational ethical climate is effective, the voice of the employees rises and the trust of the employees in their organizations increases, which strengthens the voice of the employees. Findings show that employees' ethical climate, voice and trust perceptions are related concepts.
Molecular genetic diagnosis and treatment of congenital hyperinsulinism: results of observation of patients with variants in the genes ABCC8 and KCNJ11
Authors: Ivanov Dmitry O. , Ditkovskaya Liliya V. , Maryina Olga I. , Turkunova Mariia E. , Suspitsin Evgeny N. , Yankovskaya Olga S.
Published: September 2023

Congenital hyperinsulinism is a rare hereditary disease characterized by inadequate hypersecretion of insulin by pancreatic -cells, clinically manifested by persistent hypoglycemia, which poses a great threat to patient survival and a high risk of developing severe neurological complications.
The article presents the results of clinical, hormonal and molecular genetic examination and treatment of 10 patients with congenital hyperinsulinism caused by mutations in the genes of ATP-dependent potassium channels (KCNJ11, ABCC8), hospitalized in Saint Petersburg State Pediatric Medical University clinic in 20102023. In all the studied patients, the disease manifested from the 1st to the 3rd day of life, and the median age of diagnosis of congenital hyperinsulinism in the study group was 1 month (min 14 days; max 3 years 9 months). In 8 out of 10 patients, a severe course of hypoglycemic syndrome was noted at the onset of the disease. According to the molecular genetic investigation results, 8 different mutations were identified: in the KCNJ11 (2/8) and ABCC8 (6/8) genes. Identical variants were found in two pairs of related patients. In children with mutations in the ABCC8 gene (n = 8), 2 variants with unknown clinical significance were identified, which were not previously described in allelic databases and scientific literature. According to the analysis of anamnestic and clinical and laboratory data, 80.0% of children, including patients with new, previously not described in the scientific literature, variants in the ABCC8 gene have a severe progressive course of congenital hyperinsulinism, requiring the appointment of insulinostatic therapy.
Deep Postseismic Creep Following Large Earthquakes Revealed by Repeating Aftershocks in the Southeastern Tibetan Plateau
Authors: Liu Shujun , Tang Chi-Chia
Published: September 2023

Large earthquake occurrence and the subsequent postseismic period are the most dramatic part of a seismic cycle that usually lasts months to years. However, the fault dynamics that account for the postseismic events are yet to be fully understood. Here, we use the repeating aftershock sequences (RASs) to investigate postseismic slips following the Mw 6.6 Lushan, Mw 6.5 Jiuzhaigou, Mw 6.1 Jinggu, and Mw 6.2 Ludian earthquakes in the southeastern Tibetan Plateau and find 135 RASs following the mainshocks. The RAS seismicity suggests that seismogenic faults began to creep in depth within a few hours after the Lushan, Jiuzhaigou, and Jinggu mainshocks. The deep creeps mainly follow a velocity-strengthening friction mode and decay with an Omori law p-value of ∼1. The results suggest that the combination of fault healing and geometry together controls deep fault behaviors. We develop two conceptual models to explain our observations. Our results provide new insights into spatiotemporal fault evolution after large earthquakes.
A Regenerative Study on the Impact of Urban Public Green Space Development on Adjacent Neighborhoods and Communities and its Potential to Contribute to Equitable Neighborhood Transformation
Authors:   , Jordan Theresa , Zahniser Max
Published: September 2023

The development of public green space in dense urban environments has become a tool for "neighborhood improvement" through leveraging parks as economic growth machines, with the intention to trigger economic impact in the surrounding areas. While economic growth and investment are value creating opportunities for cities and their residents, it is important to acknowledge that exploitive practices and inequitable distribution of economic and social benefits, lead to exacerbating existing wealth disparities in urban areas, which might result in neighborhood change, gentrification, and displacement of marginalized community members. The purpose of this case study research is to explore the impact of two urban greenway projects on the socio-economic and cultural systems of the neighborhoods and communities they are embedded in, in order to understand their role in neighborhood change. Through this inquiry, I examine the High Line in New York City and the Rail Park in Philadelphia, with the goal to learn from the challenges and successes of the projects and understand if urban public green space has the potential to contribute to system regeneration and equitable neighborhood transformation. The results of this research are analyzed using regenerative frameworks; regenerative practices emerged from indigenous worldviews, that understand systems as a whole and prioritize system health when solving complex issues. While acknowledging the value of economic growth resulting from the development of urban public green space, this research proposes that developers must practice meaningful community engagement and neighborhood residents must receive ownership in their communities' appreciation, in order for the development to contribute to system regeneration and equitable neighborhood transformation, and to maintain the cultural and demographic diversity of a place. Instead of viewing equitable development strategies as a service to the community or as a means to retrospectively mitigate the adverse effects of development, centering equity through building community capacity and establishing community ownership, is key. The regenerative approach highlights that granting the community a share of the social and economic benefits that urban public green space development generates, can enable the community to rise with the economics of the neighborhood, and might therefore solve issues of displacement. When capable of creative problem solving, transparency, and a shift in mindset, developers can therefore become participants in a healthier local living economy, instead of an extracting system, which results in mutual benefits that allows all parties to be better off.
Can we have it all?
Authors: Ward Elaine , Shonkoff Eleanor , Carlson Cynthia , Stuetzle Christopher
Published: September 2023

Merrimack College is a Catholic Augustinian College. This single institutional case study shares the work of faculty and the College to institutionalize community engaged research through the development of a Community Engaged Action & Research Cluster (CERC). Through the case study, we elucidate the sphere of influence of faculty with regard to community engagement and the ways in which that sphere of influence can add value to individual careers and the institution as a whole. This case study also demonstrates the impact of institutional engagement initiatives on faculty research and civic engagement in food justice.
SANATTA NARKİSSOS ÖYKÜSÜNÜN TEMSİLİ VE SALVADOR DALİ’DE NARKİSSOS METAMORFOZU
Authors: Kaplan Mehmet Akif , Koç Ali
Published: September 2023

Yunan mitolojisinde yer alan Narkissos hikayesi M.S. 1. Yüzyıl’da edebiyat alanında ele alınmıştır. M.S. 8. Yüzyıl’da şair Ovidius tarafından yeniden yazılmış olan Narkissos hikâyesi bir çok sanatçının ilgisini çekmiş ve onlara ilham kaynağı olmuştur. Narkissos öyküsü 20. Yüzyıl’a kadar sanatçılar tarafından suda kendini seyre dalan yakışıklı ve güzel bir delikanlı olarak resmedilmiştir. Modernizme kadar yapılan bu resimler cezbedici güzelliğiyle hikâyede anlatılan Narkissos’u temsil eder. Modern dönemde Salvador Dali Ovidius’un yazdığı hikayeden hareketle Narkissos öyküsünü sürrealist bir anlatımla ele alır. Dali’nin yapmış olduğu “Narkissos’un Metamorfozu” adlı eser Narkissos’un çekici güzelliğini temsili bir betimlemeyle yansıtmaz. Sanatçı eserini gerçeküstücü bir anlayışla yapmış ve sembolik öğelere de yer vermiştir. Bu çalışmanın amacı Narkissos hikayesini ele alan ressamların konuyu temsil etme biçimleri üzerinde tespitler yaparak Salvador Dali’nin “Narkissos’un Metamorfozu” adlı eserinin önceki ressamların çalıştığı Narkissos temalı resimlerden farkının ne olduğunu ele almaktır. Bu araştırmada betimsel araştırma yöntemi kullanılmıştır. Araştırma kapsamında Narkissos öyküsünü çalışan sanatçılar belirlenmiştir. Araştırmaya konu olan hikayenin temsilleri üzerine incelemeler yapılmıştır.
An Android e-Learning Application to Support Academic Learning: Design, Development, and Implementation of a Case Study
Authors:   Department of Electrical Engineering, Universitas Tanjungpura, Indonesia, Tjahjamoorniarsih Neilcy , Putra Leonardus Sandy Ade , Kusumawardhani Eka , Pramadita Suci , Gunawan Vincentius Abdi
Published: September 2023

After the pandemic, Indonesia became one of the countries that imposed a new normal for all levels of society with various sectors of life. The education sector is one of the areas most highlighted in the new normal change. Various policies and learning methods have been attempted to implement distance education. In the current new normal, distance learning is a beneficial method in implementing education in Indonesia. The delivery of learning materials is carried out by sending materials and meeting face-to-face online using video conferencing applications and materials provided on online storage services. Both methods are now available on separate platforms and have not been integrated into one platform, making it difficult for users. It has shortcomings in terms of optimization in providing learning services. In addition, the method used today still has several weaknesses, such as adjusting the learning schedule, understanding that is more difficult to accept because it is done online and also not yet integrated between face-to-face materials and media on a mobile device. This study aims to design an Android-based e-learning application that can assist students’ learning process and help distribute learning materials. The application is designed to meet the needs of students in understanding the material more optimally and can be done without being limited in time. The results of research that have been carried out on student satisfaction obtained a percentage level of 94% which stated satisfaction in the use of learning applications. Satisfaction with the help of the application says that e-learning applications can improve academic abilities and skills in the fields they study.
The Effect of Using Augmented Reality Module in Learning Geometry on Mathematics Performance among Primary Students
Authors:   the Faculty of Educational Studies, Universiti Putra Malaysia, Selangor, Malaysia, Nadzri Ainur Yusra Nabila Mohd , Ayub Ahmad Fauzi Mohd , Zulkifli Nurul Nadwa
Published: September 2023

There are many Augmented Reality (AR) applications in smart devices, but their use in education is less focused and does not meet the current syllabus. AR has a great potential to be used in education, especially in introducing abstract concepts. To use augmented reality in education, students and teachers must follow teaching and learning guidelines. Therefore, this study implied the development of an educational module with augmented reality in Geometry, specifically under Space, following the standards-based curriculum for primary school (KSSR) Year 4 lessons. This study aims to determine the effects of using a module with AR (GeomAR3) on student performance in learning Geometry compared to a traditional module (Geom3). This study was conducted quantitatively following a quasi-experimental design with a pre- and post-test. Fifty-nine (59) Year 4 students were involved in the study from a school selected through purposive sampling, with 29 of them as an experimental group and the remaining 30 as a control group. The point of assessing student performance is seen through the implementation instrument, such as a pre-test, a post-test, and a delayed post-test. The study data were analysed using Multivariate Analysis of Covariance (MANCOVA) with the pre-test score as a covariate. The results show a significant difference in student performance on the overall mean score for the post-test (F (1,59) = 33.848, p = 0.000; eta squared = 0.377) and the delayed post-test (F (1,59) = 14.740, p = 0.000; eta squared = 0.208), with the experimental group significantly better than the control group. In conclusion, the use of modules with AR was found to improve students’ achievement in learning Geometry due to the factor of the ability to visualize clearly, strengthen students’ long-term memory, and gain conceptual understanding through the experience shown by AR.
A review of few-shot image recognition using semantic information
Authors: Guo Liyong , Marlisah Erzam , Ibrahim Hamidah , Manshor Noridayu
Published: September 2023

In recent years, the utilization of deep learning techniques has been employed in the field of image recognition with the aim of improving performance. However, deep learning demands a substantial amount of labeled data for model training, a process that is both expensive and time-consuming. In order to tackle this particular difficulty, the approach of few-shot learning (FSL) has emerged as a viable alternative. FSL, or Few-Shot Learning, is a computational approach that aims to replicate the cognitive processes observed in humans. By using a small set of examples and experiences, FSL enables the acquisition of new concepts. Research in the field of FSL has investigated many approaches to extracting the highest amount of information from limited data or making use of affordable and easily accessible sources of information. Researchers have been incorporating outside data into FSL techniques more frequently. This paper conducts an in-depth exploration of leveraging semantic information to enhance few-shot learning. By reviewing papers from the last five years in WOS, IEEE, and Science Direct (some papers in arXiv are also used), this study delves into the strategies employed to bridge the gap between visual and semantic information. The review extends to encompass zero-shot learning, which is considered a subcategory of FSL, enriching the analysis. Moreover, this paper identifies the potential of employing semantic information to enhance fine-grained few-shot (FGFS) learning. Techniques such as direct projection and the application of generative adversarial networks (GANs) emerge as promising avenues to accomplish this enhancement.
Comparison of the Physical Properties of Three Resin-Based Root Canal Sealers: An In-Vitro Study
Authors: Sarraf Pegah , Ghabraei Sholeh , Mohammadi Zahra , Noori Faranak , Chitsaz Nazanin
Published: September 2023

Objectives: This in-vitro study aimed to evaluate the physical properties of three resin-based root canal sealers, including BETA-RCS, AH26, and Adseal.
Materials and Methods: Flowability, film-thickness, solubility, and radiopacity of BETA-RCS, AH26, and Adseal sealers were evaluated according to ISO 6876/2012 specifications. Three samples of each sealer were used to test each of the properties.
Results: The results revealed that the flow rate (mm) of BETA-RCS, Adseal, and AH26 were 23.06±1.58, 22.5±4.23, and 21.85±1.71, respectively. Film-thickness values (µm) for BETA-RCS, Adseal, and AH26 sealers were 52.33±2.51, 18.66±0.57, and 52±2, respectively. No significant difference was observed regarding film-thickness between AH26 and BETA-RCS (P>0.05), while Adseal showed significantly lower film-thickness (P˂0.05). The highest and lowest solubility were related to BETA-RCS and Adseal, respectively. However, all sealers had acceptable solubility and radiopacity.
Conclusion: The findings of the current study suggested that all three root canal sealers including BETA-RCS, AH26, and Adseal had similar properties based on ISO 6876 standard criteria. As such, they could be viable choices for facilitating effective root canal procedures. Further long-term clinical studies are warranted to assess their performance and success rates in actual endodontic cases.
Aging and Disability: An Exploration of Barriers and Facilitators to Community Living
Authors: Fabian Ellen S. , Havewala Mazneen , Zhu Qianyu , Deschamps Ann
Published: September 2023

Demographic data projections for the United States indicate a significant increase in the population of older persons with disabilities. The Americans with Disabilities Act (ADA) mandates community access for individuals with disabilities, including older individuals who are aging with or aging into disabilities. However, there is limited research regarding the knowledge and the use of the ADA among this population specific to their perceptions and experiences regarding barriers and facilitators to community access and participation as mandated under the Act. The purpose of this qualitative focus group study was to explore the perceptions and experiences of a sample of older adults with disabilities regarding their community access, and their knowledge and utilization of the provisions of the ADA to facilitate community participation. Analysis of results identified three predominant themes within this sample of older adults: experiences with structural and attitudinal barriers to community access leading; fear of loss of autonomy and independence in the community, and how they deploy; coping and advocacy strategies to address barriers. Recommendations for improving ADA knowledge, access, and utilization among the population, as well as senior service providers, are also addressed.