bluuebunny/crossref_metadata_2025 huggingface dataset:
Does the Side of Deviation of Nasal Septum have Concomitant Predictive Relation with Side of Sphenoid Septum Deviation?
Authors: Venkatesh G , Gugapriya TS , Kumar N Vinay , Kumari SD Nalina
Published: March 2022

Introduction: The asymmetric hidden sphenoid sinuses get separated by a bony septum which rarely lies in the median plane. Deviated Nasal Septum (DNS) formed by bony and cartilaginous parts can be identified by clinical examination. Paucity of literature about the concomitant side deviation of both the septum, has been found. Aim: To find the predictive relation between the side deviation of nasal and sphenoid septum. Materials and Methods: A cross-sectional study was undertaken with coronal CT image sets of paranasal air sinuses at Chennai Medical College Hospital and Research Centre, Trichy, Tamil Nadu. Images of subjects above 18 years of age without chronic sinusitis blocking Infundibulo-osteal complex, space occupying lesion, previous sinonasal surgeries, and inflammatory polyps were included from December 2016 to January 2017. In 130 source image sets, side deviation of the nasal septum and sphenoid septum were observed and categorised. The data were analysed using IBM SPSS Statistics for Windows, version 26 and a p-value of <0.05 was considered as statistically significant. The agreement of corresponding side deviation of nasal and sphenoid septum was tested using chi-square and Kappa test. Results: The DNS was noted in 94.6% (123 of 130) of images. The right, left and median deviations were observed in 50.8% (66 of 130), 43.8% (57 of 130) and 5.4% (7 of 130), respectively. The sphenoid septum deviations of right, left and median was noted in 43.1% (56 of 130), 36.9% (48 of 130), and 19.2% (25 of 130), respectively. The right deviated sphenoid septum was seen in 39 out of 66 right DNS images and left deviated in 29 out of 57 left DNS images. Chi-square showed statistical significance (p-value=0.0031) and kappa [0.231 (SE of kappa=0.064, 95% confidence interval: from 0.104 to 0.357)] was assessed as a fair agreement between the observed values. Conclusion: The fair agreement between sides of DNS with position of sphenoid septum concludes that DNS could be a probable predictor of position of sphenoid septum.
Treatment of Large Hepatocellular Carcinoma using Transarterial Chemoembolisation Combined with Sorafenib
Authors: Madhu SD , Lalsawmpuii Fanai , Harish B , Suryavamshi Nilesh , Lokesh KN , Rajeev LK , Usha Amritham
Published: March 2022

Introduction: Hepatocellular Carcinoma (HCC) is the most common primary malignant tumour of liver, accounts for 90% of all primary hepatic tumours, with second most common cause for cancer-related deaths worldwide. Majority of HCC presents in Barcelona Clinic Liver Cancer (BCLC) intermediate stage (B), for which Transarterial Chemoembolisation (TACE) is the most commonly available treatment . Even though overall prognosis of these locally advanced tumours is poor, significant improvement can still be made in overall survival and recurrence free survival with locoregional therapy like TACE. Aim: To assess the efficiency, safety and limitations of TACE in large HCC with specific focus on importance of appropriate patient selection. Materials and Methods: The study was conducted on 30 histopathologically proven cases of HCC with BCLC intermediate stage. All cases underwent TACE followed by repeat TACE or treated with sorafenib depending on their response and clinical status. Treatment-related complications, treatment response, recurrence free survival was assessed. Results: Of the 30 cases, six cases had lesion size less than 5 cm, six cases with lesion size 5-10 cm and remaining 18 cases had lesion size more than 10 cm, with the largest lesion being 16 cm. Twenty-one cases had elevated Alfa Fetoprotein (AFP), chronic liver disease was seen in 10 cases, with five cases having at least two lesions. Total 50% of cases with lesion less than 5 cm showed complete response at 15 months, four of six cases with lesion size of 5-10 cm showed partial response at 15 months, other two cases were lost for follow-up. Cases with lesion size more than 10 cm showed mixed response, at 15 months follow-up, 10 cases showed stable response, six cases showed progressive disease and two patients died due to liver dysfunction. Conclusion: Transarterial Chemoembolisation combined with sorafenib prolonged the overall survival in selected large tumours with high disease burden status.
Multiple Myeloma Presenting as Chest Wall Lesion: A Case Report
Authors: Patil Prakriti R , Yeli Ravi Kumar , Pati Shivanand V , Patil Satish D
Published: March 2022

Multiple myeloma is defined by >10% of clonal plasma cells in bone marrow or biopsy-proven extramedullary plasmacytoma and by the evidence of end-organ damage including bone lesions and renal insufficiency. It usually occurs in the age group of 50-70 years with higher incidence in males. Swelling on the chest wall is an uncommon presentation of multiple myeloma. In this case of 85-year-old male patient, two soft tissue density lesions on the posterolateral and anterior chest wall, multiple punched-out lesions in the skull, diffuse osteopenia and multiple lytic lesions were noted in ribs, sternum and thoracic spine, with evidence of myeloma cells in the bone marrow and bence jones protein in urine. Radiologic imaging plays an important role in providing a provisional diagnosis and thus, helping the clinician in such cases.
Evaluation of Coccyx Variability using Multislice Computed Tomography- A Cross-sectional Study
Authors: Raghu SR , Shankara K , Sachin T , Shashikiran BR
Published: March 2022

Introduction: Coccyx is the terminal vestigial segment of human spine. There is a lack of data on the structure of coccyx causing hindrance in the treatment aspect of coccydynia. Aim: To determine type of coccyx, number of coccygeal segments, prevalence of sacrococcygeal, intercoccygeal fusion and coccygeal spicule of human adult coccyx using pelvic Computed Tomography (CT) scans. Materials and Methods: A cross-sectional study of 49 adult patients was done who underwent CT scans for benign clinical conditions like ureteric colic, abdominal pain evaluation in Hassan Institute of Medical Sciences, Hassan, Karnataka, India. The coccyx bone was evaluated for number of segments, sacrococcygeal and intercoccygeal fusion and prevalence of spicules and configured as types I-IV according to Postacchini F and Massobrio M classification. Chi-square test was used to find association of the type of coccyx with age and gender. Results: Type I coccyx (32, 65.3%) was the most common type followed by type II (9, 18.3%). Majority had four coccygeal segments (39, 79.6%). The sacrococcygeal fusion was seen in 13 (26.5%) and intercoccygeal fusion was observed in 41 (83.7%) patients. Coccygeal spicule was seen in 21 (42.9%) subjects. The tip of coccyx was retroverted in only 3 (6.1%) patients. The terminal coccygeal segment showed ventral angulation in 8 (16.3%) cases. Conclusion: In present study, Type I coccyx was most common with four coccygeal segments. Intercoccygeal fusion was more commonly seen than sacrococcygeal fusion. Comprehension of in vivo structure of coccyx through CT scans will help in care of patients with coccydynia.
Evaluation of Lateral Flow Assay for the Diagnosis of Cryptococcal Meningitis and its Comparison with the Gold Standard and Other Laboratory Tests
Authors: Malavika Kottarathil , Premamalini Thayanidhi , Kindo Anupma Jyoti
Published: March 2022

Introduction: Cryptococcosis is a potentially fatal fungal disease affecting both immunocompromised and immunocompetent individuals. Hence, a Point Of Care Test (POCT) is required with higher sensitivity and specificity (100%), for the rapid detection of cryptococcosis which will be life saving for the patient. Aim: To evaluate the usefulness of Lateral Flow Assay (LFA) for rapid detection of Cryptococcal Antigen (CrAg) from Cerebrospinal Fluid (CSF) sample. Materials and Methods: This diagnostic study was conducted in Mycology Laboratory, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India, over a period of six months (June 2019-November 2019). The CSF samples (n=37) from patients with suspected meningitis were considered for the study. Direct microscopy with gram stain, negative stain and histopathological stains was performed for all the CSF samples. Culture was done on basal medium, enriched media and special media. Cryptococcus genus specific Polymerase Chain Reaction (PCR) was also performed to confirm the isolates grown on the culture. Serological tests like Latex Agglutination Test (LAT) and LFA were also performed on all the samples. The LFA results were compared with microscopy, culture and LAT. Results: Among the 37 suspected meningitis patients, three grew Cryptococcus in culture which was considered as the gold standard in the diagnosis of Cryptococcal Meningitis (CM). Direct microscopic techniques had 100% specificity however their sensitivity was less i.e., 67%. LAT had a sensitivity of 100% and specificity of 94%. However, LFA in present study had a very good sensitivity, specificity, Positive Predictive Value (PPV) and Negative Predictive Value (NPV) (100%). Conclusion: LFA for the detection of CM is considered to be an effective method when compared to the other conventional and serological methods with higher sensitivity and specificity. Hence, in present study authors evaluated the use of LFA in diagnosis of CM and found that this assay when used as a POCT, can give the results in short duration. Considering this as a pilot study, further studies including higher number of samples are essential to confirm the effectiveness of the findings.
Impacts of Climate Change on the Water Sector in Mexico
Authors: Hermes Ulises Ramirez Sanchez , Montiel Aida Lucia Fajardo , Alma Delia Ortiz Bañuelos , Villaseñor Odila De la Torre
Published: March 2022

Climate and the water cycle are intimately related; so, any change in temperatures and precipitation patterns estimated for different climate change scenarios will have an impact on the availability of water resources. The objective of this study is to present a set of regional temperature and rainfall projections for Mexico under the IPCC's AR6 climate change scenarios and estimating the possible impacts of climate change on Mexico's water resources. A set of regional temperature and rainfall projections for Mexico under the IPCC's AR6 climate change scenarios during the present century were generated by the Climate Change Knowledge Portal (CCKP) of the World Bank and together with the projections of soil moisture, Normalized Difference Vegetation Index (NVDI), Standardized Precipitation Evapotranspiration Indices (SPEI) and droughts will be evaluated. The vulnerability of Mexico's water resources. The regional models for Mexico under the IPCC AR6 climate change scenarios show temperature increases ranging from 0.5 to 5 °C, while the % change in rainfall will range from -20.3% to 13.5% depending on the scenario and analysis period. Low soil moisture (mm), negative changes in NDVI and SPEI 12 show that the North, West and Bajío areas presented reductions in precipitation and increase in temperature that caused a severe deficit of soil moisture and water stress in plants considering these areas with scarce vegetation and presence of semi-permanent meteorological drought. Under these scenarios it is expected that practically the entire country will be subjected to moderate droughts (Central and South) to extremely strong (North) that will last and sharpen between now and the end of the century. These conditions have already been registered in the main hydrological basins of Mexico and if adaptation and mitigation measures are not adopted, the availability of water is put at risk and with it the food security of the country. Also, in addition to the decrease in rainfall, it is estimated that they are more intense with the presence of extreme events, which will increase the vulnerability of some basins throughout the country, in the Central and Northern areas with extreme drought events, while in the Southeast with floods. Both scenarios would put at risk the availability of water both in quality and quantity throughout the country. To reduce the effects of climate change on water resources in Mexico, it is necessary to design and prioritize adaptation actions and implement mitigation measures that avoid intensifying the effects of climate change in the most vulnerable hydrological regions of the country.
Bioaccumulation Potential of Seagrass (Halophila sp.) for Mercury in the Selected Coastal Areas in Malita, Davao Occidental
Authors: Joy Tuba Junarie , Avenido Pedro , Llameg Marlyn , Elemino Michelle , Cañeda Jopy , Roquero Dexter , Hilis Romeo , Dalogdog Jessa May , Meralles Jamaica , Tabaranza Georgie
Published: March 2022

This research aims to determine the potential of seagrass Halophila sp.  in absorbing mercury in the selected coastal barangays in Malita, Davao Occidental. The study employs a quantitative type of research where strategies focus on quantifying the collection and analysis of data. The study was conducted from October 2020 to December 2021 in the three selected coastal Barangays in Malita, Davao Occidental namely Brgy.Culaman, Brgy. New Argao and Brgy. Tingolo. Transect line quadrat method was used to determine the percent cover and shoot density of seagrass. Using this method, the point of seagrass occurrence up to the outer limit where seagrasses disappears was determined. There were three (3) stations and three (3) transect lines were laid for each station with an interval of 50m. Five (5) quadrats were also laid in the seagrasses along the 50 meter transect line positioned perpendicular to the shoreline. The seagrasses were collected in each quadrat and the samples were transported to Davao Analytical Laboratories, Inc. for mercury analysis. The highest mean percent cover (10.27%), shoot density (128.91 shoots/m2) and Hg accumulation (572.9ppb) was recorded in Brgy. Tingolo, Malita, Davao Occidental while the lowest result was obtained by Brgy. Culaman, Malita, Davao Occidental. Halophila sp. has the capability to accumulate mercury content and exceeds the standard level of 20 ppb. There were no significant differences in the percent cover and Hg accumulation of seagrass Halophila sp. while significant difference is observed in the shoot density. However, there is a positive relationship (.664) between the shoot density and mercury concentration of Halophila sp.
The Effect of Arthrospira platensis (Phormidiaceae) on the Acute Toxicity of Artemeter Lumefantrine in Malaria Patients
Authors: Theresia Njuabe Metoh , Keita-Kerry Asangbe , Sanda Antoine Kada , Ghislaine Yensii Nina , Ngo-Matip Marthe-Elise , Moses Mbofung Carl
Published: March 2022

Malaria has remained one of the leading causes of morbidity and mortality in most developing countries. This pathology is caused by the Plasmodium spp. Current World Health Organization (WHO) guidelines for the treatment of uncomplicated falciparum malaria recommends the use of artemisinin-based combination therapy (ACT). Arthrospira platensis is a microscopic filamentous alga that is rich in proteins, vitamins, essential amino acids, minerals and essential fatty acids like -linolenic acid (GLA). The current study was carried out to evaluate the effect of Arthrospira platensis on the liver and kidney toxicity induced by ACT. Malaria patients were randomized into two groups to receive therapeutic dose of either artemether-lumefantrine 20/120 mg (group 1) or artemether-lumefantrine 20/120 mg + Arthrospira platensis 8 g daily (group 2) as an adjunct therapy and follow-up for 7 days (D). After treatment, the activity levels/concentrations of liver and kidney biochemical markers (ALT, AST, ALB, UREA, CREAT) were analyzed. Both pre- and post-treatment samples were analyzed, and the results gotten compared with control group made up of malaria negative patients. Serum activity of selected biomarkers (ALT, AST, ALB, UREA) of malaria patients were statistically significant (P<0.05) on D0 when compared to that of malaria negative patients. The serum activity of CREAT though not statistically significant (P>0.05), increased compared to malaria negative patients. The serum level of ALT, AST, UREA and CREAT increased from D0 to D3 and decreased on D7 after treatment while ALB decreased from D0 to D3 and increased on D7 in both groups when compared with the negative control group. The concentration of these biochemical markers varied across the groups from D0 to D7. The results obtained from this study indicate that Arthrospira platensis has a positive effect on the liver and kidney toxicity induced by ACT and hence could be administered together with ACT in malaria treatment.
Impact of Malaria among Different Age Groups in Pregnancy in Rivers State
Authors: Felix Eedee Konne , Lynda Kadi Giami , Beatrice Wobiarueri Moore-Igwe , Nyebuchi Jonathan , Oroma Ethel Konne , Gloria Ngozika Wokem
Published: March 2022

Studies have shown that pregnant women are vulnerable to malaria parasitemia. Unfortunately, less attention has been paid to the effect of age group on malaria parasitemia among this group of subjects. The aim of this study was to determine the most age vulnerable age group of malaria parasitemia among pregnant women. It was a hospital-based study carried out in two selected health institutions in Rivers State. A simple random sampling technique was used to select the areas of study as well as the 400 participants used for the study. A well-structured questionnaire was used to collect the socio-demographic data of the subjects within the age range of 21–40years. Venous blood samples of the subjects were collected from the subjects and examined for the presence of malaria parasites using standard procedures. The results obtained from the health institution located in urban region of Rivers State (Braithwaite Memorial Specialist Hospital) showed the prevalence rate of 36.4% in the group within the age of 21-25 years, 36.1% among age range of 26-30 years, 22.5% for 31-35 years and 23.1% for the pregnant women within the age of 36-40 years. The results obtained from the health institution located at semi-urban region of the state (General hospital Bori) showed prevalence of 44.2%, 23.0%, 35.7% and 41.7% respectively. There was a significant difference the prevalence of malaria among the age groups in both health facilities, P= 0.0001. This study has shown that younger pregnant women especially those in their 20s are more prone to malaria parasitemia than older women in the Rivers State.
Design and Selection of Novel Kinase Inhibitors Implicated in Alzheimer’s Disease by High Throughput Virtual Screening
Authors: Kumar Diwakar Sunil , Anoop Singh
Published: March 2022

CDK5 (cyclin dependent kinase 5) is a promising target for treating a variety of neurodegenerative illnesses. The discovery of effective and selective CDK5 inhibitors that engage the polar side chains of the ATP-binding pocket as well as establish specific hydrogen bonds with the kinase has made significant progress. To find novel prospective CDK5 inhibitors with improved effectiveness, ADME characteristics, and a large margin of safety. High throughput virtual screening employing flexible docking was used to screen 2,50,000 compounds from the Specs database against the CDK5 crystal structure (PDB ID: 1UNL). The docking simulation was performed using HTVS first, then SP, and finally XP. The interaction pattern to the receptor with fresh lead candidates has been found and selected based on the GLIDE docking score. The lead moiety in the co-crystallized roscovitine with CDK5 complex retains critical H-bonding patterns while also introducing hydrophobic interactions with Ile10 and Leu133. Selected hits demonstrate hydrophobic interactions with Asn 144, Gly 13, and Ala143 within the ATP cleft in a comparable way to reference compounds (Roscovitine). The lead compound's binding pattern revealed by GLIDE docking experiments demonstrated that molecules bind to the kinase's well-conserved catalytic pocket.
IMPLANTE IMEDIATO COM PROVISIONALIZAÇÃO IMEDIATA: UMA REVISÃO DE LITERATURA DOS FATORES ENVOLVIDOS NA ESTABILIDADE PERI- IMPLANTAR
Authors: Fernandes Danielle , Duarte Fabiana , Bittencourt Sandro
Published: March 2022

Após a exodontia de uma unidade dentária o alvéolo passa por um processo de remodelação, mesmo após a implantação imediata, o que pode interferir esteticamente no tratamento executado. A estabilidade do tecido peri-implantar neste contexto é um dos aspectos que contribui com a estética e pode sofrer influência de vários fatores, dentre os quais biótipo gengival, tipo de cirurgia(com ou sem retalho), espessura da tábua óssea, distância entre implante eparede alveolar vestibular, posicionamento do implante e preenchimento do“gap”, que serão abordados neste trabalho. Vislumbrando uma Odontologiabaseada em evidências alguns artigos científicos foram revisados e aspectos quparecem interferir nas transformações peri-implantares foram pontuados. Apesarda falta de padronização entre as metodologias dos estudos consultados, o quedificulta a comparação entre os resultados e estabelecimento da superioridadeentre materiais utilizados, foi possível concluir que o biótipo gengival exerceinfluência na estabilidade dos tecidos peri-implantares. Além disso nota-se anecessidade de estudos clínicos controlados e com metodologia bem descritaà fim de facilitar as comparações dos resultados.
PLACA BACTERIANA DENTAL COMO UM BIOFILME
Authors: Casais Paula Milena Melo , Moreira Iolanda Souza , Moreira Luiz Gaudencio Passos , Ribeiro Érica Del Peloso , Rapp Gisela Estela
Published: March 2022

A placa bacteriana dental é definida como um conglomerado de microrga- nismos que se encontram adsorvidos aos tecidos moles e duros da cavidade bucal, inseridos em uma matriz contendo polissacarídeos, exopolissacarídeos e componentes salivares. Pode desencadear várias patologias na cavidade bu- cal, como cárie, gengivite e periodontite. Assim, objetiva-se revisar a literatura acerca das características que envolvem a sua denominação atual em biofilme dental. Pela literatura revisada pode-se apreender que o entendimento da placa bacteriana como um biofilme dental implica na compreensão de uma estrutura de microrganismos complexa, que contém uma ou mais espécies bacterianas, se desenvolve na interface dentária e exibe heterogeneidade espacial. Cerca de mil espécies de microrganismos podem ser encontradas nos biofilmes sob as superfícies dentais. Na cavidade bucal, o biofilme é composto por microorga- nismos que se aderem a uma película, composta por glicoproteínas salivares, fosfoproteínas, lipídeos e componentes do fluído gengival. Trata-se de uma organização na qual ocorre a formação de canais que facilitam a comunicação intercelular e a proteção contra a ação de agentes antimicrobianos e a resposta imune do hospedeiro.
AVALIAÇÃO DA COBERTURA ÓSSEA POR TOMOGRAFIA COMPUTADORIZADA DE FEIXE CÔNICO NA ODONTOLOGIA: REVISÃO DE LITERATURA
Authors: Ferreira Paula Paes , Nascimento Ana Carla de Souza , Bittencourt Marcos Alan Vieira , Rebello Iêda Margarida Crusoé Rocha
Published: March 2022

O avanço tecnológico em diagnóstico por imagem na Odontologia culmi- nou no desenvolvimento da Tomografia Computadorizada de Feixe Cônico (TCFC), a qual representa de maneira fiel e tridimensional a anatomia óssea e dentária, sem sobreposição de estruturas, expondo o paciente a uma dose de radiação inferior, com custo reduzido, quando comparada a Tomografia Computadorizada Convencional. Diante da riqueza de informações forneci- das pela TCFC, a utilização da mesma para diagnóstico e planejamento em diversas especialidades da Odontologia é de grande valia para o sucesso do tratamento. Portanto, o objetivo desse trabalho é mostrar a utilização da TCFC, suas vantagens e desvantagens na prática odontológica.
AGGREGATIBACTER (ACTINOBACILLUS) ACTINOMYCETEMCOMITANS E A DOENÇA PERIODONTAL: UMA REVISÃO DA LITERATURA
Authors: França Helene Marie Rodrigues Carvalhal , Santos Renata Souza , Da Costa Elizabeth Maria , Rapp Gisela Estela
Published: March 2022

A  doença  periodontal  é  uma  doença  inflamatória  de  origem  multifatorial. Papel relevante vem sendo atribuído aos microrganismos na etiologia desta doença. O Aggregatibacter actinomycetemcomitans é um dos mais estudados patógenos associados à doença periodontal. O presente trabalho visa revisar a literatura acerca dos fatores de virulência deste patógeno, que são capazes de impedir a resposta imune do hospedeiro, potencializando assim a destruição dos tecidos periodontais. De acordo com a literatura revisada pode-se apre- ender que o A. actinomycetemcomitans é um microrganismo Gram-negativo, que apresenta diversos fatores de virulência como as leucotoxinas, fímbrias, lipopolissacarídeos,  adesinas,  vesículas  de  membrana  extracelular,  fatores imunossupressores e perturbadores das funções neutrofílicas, da inibição do crescimento das células epiteliais e fibroblásticas, além da ativação das células B policlonais entre outros. Assim, justifica-se que A. actinomycetemcomitans é um importante patógeno periodontal que está associado principalmente com a periodontite agressiva localizada e a sua ocorrência e virulência na saúde ou na doença periodontal são população e sorotipo dependentes. Nesse contexto, o presente trabalho tem como objetivo revisar a literatura acerca deste patógeno,
A INFLUÊNCIA DA LUMINOSIDADE NA CONFECÇÃO DE COROAS EM CERÂMICA NOS LABORATÓRIOS DE PRÓTESE DENTÁRIA
Authors: De Andrade Cristiano Goés , De Rocha Paulo Vicente Barbosa
Published: March 2022

Na Odontologia, tanto seleção quanto harmonização das cores, são extrema- mente importantes para o sucesso dos métodos terapêuticos restauradores. Faz-se necessário, então, um ambiente favorável à efetivação dessas atividades. Em face dessas considerações o estudo experimental possui como Objetivos: verificar a influência da luminosidade na execução das coroas em cerâmicas nos laboratórios de prótese, analisar a relação entre a qualidade de luminosidade dos laboratórios de prótese; a eficácia na execução das próteses cerâmicas e avaliar o percentual de coincidência entre a cor informada pelo dentista e a executada pelo técnico em prótese dentária. Material e Métodos: optou-se por elaborar lista contendo os laboratórios de prótese, que fornecem serviços para os alunos e professores da 9ª turma do Curso de Especialização em Pró- tese Dentária da ABO–Seção/BA. Escolheu-se aleatoriamente 10 laboratórios, procedeu-se medição da luminosidade com um luxímetro digital MLM/1011, tomou-se 03 medições, em três pontos diferentes do mesmo recinto, e utilizou--se o Easyshade para verificar a efetividade na elaboração de uma coroa de cerâmica. Resultados: a maioria dos laboratórios investigados encontravam-se com a intensidade de luz fora dos limites preconizados; laboratórios em que a intensidade de luz estava entre os limites, houve uma maior efetividade na tomada de cor; verificou-se uma grande discrepância na efetivação da cor por parte dos laboratórios que utilizavam exclusivamente a luminária de bancada para conferencia final do trabalho. Conclusão: as condições de iluminação do ambiente de trabalhos dos técnicos em prótese dental afetam a seleção de cor, principalmente, naqueles que possuem iluminação artificial.
QUANDO INICIAR OS CUIDADOS BUCAIS DO BEBÊ?
Authors: Nunes Ana Carla Robatto , Costa Renato Magalhães , Bahia Lavyne Oliveira , Wanderley Flávia Godinho Costa , Rocha Hugo Martins
Published: March 2022

Objetivo: Analisar a opinião de Odontopediatras e Cirurgiões-Dentistas que atendem crianças sobre os cuidados bucais necessário para saúde do bebê. Material e métodos: Estudo prospectivo, com delineamento transversal, ca- ráter exploratório e abordagem quantitativa. A amostra foi composta por 53 profissionais e a coleta de dados foi conduzida em Salvador (BA), entre feve- reiro e novembro de 2013, com o uso de um questionário estruturado com 15 questões. Resultados: Entre os profissionais incluídos no estudo, 92% eram do sexo feminino e 66% tinham pós-graduação em Odontopediatria. A fase edêntula foi citada como o momento ideal tanto para acontecer o primeiro atendimento odontológico (90%) quanto para iniciar a higiene bucal do bebê (98%), sendo a gaze estéril (47%) associada à água filtrada (79%) a combinação mais recomendada. Após a irrupção do primeiro dente decíduo, a indicação mais citada foi o uso da dedeira (38%) associada ao dentifrício não fluoretado (45%), recomendação modificada para escova de dente (98%) com dentifrício não fluoretado (53%) após a irrupção do primeiro molar decíduo. Caso o bebê apresentasse atividade de cárie, 74% recomendariam o uso de dentifrícios flu- oretados. Os voluntários preconizavam dentifrício fluoretado em quantidade semelhante a um grão de arroz para crianças menores de quatro anos (80%) e do tamanho de um grão de ervilha nos pacientes maiores que essa idade (75%). Conclusão: Os voluntários recomendam um início precoce de cuidados bucais nos bebês, se mostram cautelosos sobre o uso de dentifrícios fluoretados na primeira infância, mas estimulam seu uso em pacientes com atividade de cárie.
ASPECTOS CLINICOS DE UMA REABILITAÇÃO COM PRÓTESES FIXAS SOBRE IMPLANTES OSSEOINTEGRADOS: RELATO DE CASO
Authors: De Andrade Cristiano Goés , Corrêa Márcio Plácido , Da Rocha Paulo Vicente Barbosa , Oliveira Fernando José , Júnior Osvaldo Naziazeno de Andrade , Bonfim Eduardo Seixas
Published: March 2022

Os implantes fazem parte do planejamento dos tratamentos reabilitadores na Odontologia, e quando empregados com critério, tem-se a possibilidade de restituir ao paciente as funções imprescindíveis do sistema estomatognático. A realização de estudos no âmbito dessa temática tem comprovado que os pacientes inválidos orais tem usufruído dos aspectos benéficos das próteses sobre implante, principalmente quando comparado com as próteses totalmente mucosuportadas. Em face destas considerações o presente relato de caso clínico, possui como Objetivo discutir os aspectos de interesse protético na reabilitação de paciente desdentado total com implantes osseointegráveis, descrevendo a execução do tratamento reabilitador protético maxilomandibular através de próteses  implantosuportadas  e  parafusadas.  Descrição  do  Caso:  Para  isso, realizou-se tratamento seqüencial de uma prótese total implanto suportada e parafusada, composto por duas etapas, sendo uma cirúrgica e uma protética, efetivadas em um intervalo de tempo de quatro meses. Consideração Final: ao final do tratamento observou-se a reabilitação maxilomandibular com próteses totais fixas sobre implantes e a melhora na auto-estima relatada pelo paciente.
CISTO DENTÍGERO: RELATO DE CASO
Authors: Azevedo Fernanda , Marchionni Antônio Márcio T. , Reis Sílvia Regina de Almeida , Medrado Alena R. A. P.
Published: March 2022

Os cistos odontogênicos podem ser classificados em dois tipos, inflamatórios e de desenvolvimento. Dentre os cistos de desenvolvimento, o cisto dentígero é o mais comum. Embora a sua etiopatogenia não esteja totalmente estabelecida, sabe-se que há uma alteração no epitélio reduzido do órgão do esmalte, com acúmulo de liquido, entre o epitélio e a coroa do dente. Objetivo: Descrever a ocorrência de um cisto dentígero em mandíbula de um paciente edêntulo total e senil, cuja ocorrência é incomum, o qual foi tratado e submetido ao controle pós-operatório. Descrição do caso: Paciente J.A.S., gênero masculino, 69 anos, compareceu ao serviço de um hospital público, queixando-se de dor na região de ramo mandibular há aproximadamente 20 anos. Ao exame extra-oral, não foi observado nenhuma alteração, nem assimetria facial. Ao exame intra-oral, foi constatado que o paciente era edêntulo total e apresentava uma pequena diminuição no volume do rebordo alveolar posterior direito, na região de ramo mandibular. Os achados imaginológicos revelaram que a unidade 48 estava inclusa, associada a uma imagem radiolúcida unilocular bem delimitada. A despeito da faixa etária do paciente, a suspeita diagnóstica foi de cisto dentí- gero. Foi realizada abordagem cirúrgica para a remoção da lesão. Os achados histopatológicos exibiram epitélio estratificado pavimentoso não ceratinizado que revestia o lúmen e presença de cápsula de tecido conjuntivo, confirmando a hipótese diagnóstica de cisto dentígero. Conclusão: Decorridos um ano e dois meses, após a abordagem cirúrgica inicial, o paciente apresenta neoformação óssea na região, sem evidências de recidiva da lesão.
IMPACTO DA HALITOSE NA QUALIDADE DE VIDA
Authors: Cotrim Barbára Nascimento , Ribeiro Leila Brito de Queiroz , Ribeiro Érica Del Peloso
Published: March 2022

A halitose é definida como ar exalado da boca que é ofensivo e desagradável aos outros e para o próprio paciente. A etiologia da halitose ainda é controversa devido à sua natureza multifatorial, porém estudos indicam que aproximada- mente 90% das causas são intra-orais, relacionando-se principalmente com a degradação de matéria orgânica em compostos sulfurados voláteis, pelas bactérias presentes na saliva, biofilme dental, dorso da língua, sulco gengival e bolsas periodontais. Classifica-se a halitose em: halitose verdadeira, pseudo-halitose e halitofobia. Tanto os indivíduos com diagnóstico definido de halitose verdadeira, quanto aqueles com pseudo-halitose ou halitofobia experimentam um  grave  problema  que  afeta  o  seu  comportamento  social.  Surge  então  a necessidade de se fazer uma abrangente avaliação do impacto do mau odor oral na vida diária dos pacientes. O objetivo deste trabalho é apresentar uma revisão da literatura sobre o impacto da halitose na qualidade de vida dos indivíduos, enfatizando os aspectos psicológicos envolvidos nesta condição, além de apresentar os instrumentos utilizados para a avaliação desse impacto.
ESTUDO COMPARATIVO DA EFICIÊNCIA E EFICÁCIA DE DIFERENTES INSTRUMENTOS PARA REMOÇÃO DE PINOS DE FIBRA COMPARATIVE STUDY OF THE EFFICIENCY AND EFFECTIVENESS OF DIFFERENT INSTRUMENTS FOR FIBER POST REMOVAL
Authors: Bragatto Giuliano , Crusoé-Rebello Ieda Margarida , Neves Frederico Sampaio , Mendes Christtson Cesar , Oliveira Viviane Maia Barreto de
Published: March 2022

Objective: The aim of this study was to evaluate the efficiency andeffectiveness of different instruments to remove fiber post (FP): longspherical diamond tip 1012 (KG Sorensen) (LSDT); ultrasonic insert withspherical diamond post, model TRI27DP-A32 (Trinks); and E5 long conicalultrasonic insert (Helse).Materials and Methods: this randomizedin vitrostudy used 30 inferior bovine primary incisors roots,endodonticallytreated, subdivided into 3 groups. A fiberglass post model DCE0.5 (FGM) was cemented in each root and removed. The followingwere evaluated: removal times; the pre and post weights removal ofthe fiberglass post; and the area change of the conduit after removalof the FP. Results: The three groups obtained times of removal the FPstatistically different from each other. The LSDT obtained the shortesttime, followed respectively by the diamond spherical post and thelong conical insert. Regarding the weight variation, only in the groupof the spherical diamond postinsert did not present a statistically significantchange. The data referring to the change in the total area revealedthat the LSDT and the diamond spherical post insert did notshow statistically significant changes, with a significance level of 5%.However, the individualized evaluation of the root thirds showed that,in the apical and middle thirds, only the spherical diamond post tipdid not promote statistically significant alterations, and in the cervicalthird only the LSDT did not promote statistically significant alterations.Conclusions: The LSDT was efficient but not effective; the diamond--shaped spherical post was effective, but not efficient; and the E5 longconical ultrasound insert was neither efficient nor effective; suggestingthat the association of the LSDT in the cervical third, and the insertionfor ultrasound pulls spherical diamond post in the middle and apicalthirds is the best option.
ABORDAGEM ESTÉTICA MINIMAMENTE INVASIVA EM PACIENTE COM DENTES CONÓIDES E DIASTEMA MINIMALLY INVASIVE AESTHETIC APROACH IN PATIENT WITH CONOID TEETH AND DIASTEMA
Authors: Araujo Nara Santos , Silva Rafaela da , Jesus Alan Araújo de
Published: March 2022

A presença de incisivos conóides demanda uma abordagem estéticarestauradora. Dentre as opções de tratamentos, destacam-se os laminadoscerâmicos minimamente invasivos. Entretanto, esta modalidaderestauradora representa um grande desafio, principalmente quandose refere aos dentes anteriores de pacientes jovens. Objetivo: Relatarum caso de harmonização do sorriso com laminados cerâmicos reforçadoscom dissilicato de lítio. Descrição do caso: Paciente do sexofeminino procurou atendimento odontológico, relatando insatisfaçãocom os diastemas e os incisivos laterais conóides reanatomizados comresina composta. Foi elaborado um planejamento para a reabilitaçãocom a confecção de laminados nas unidades 13 a 23. Inicialmente foramobtidos modelos de estudo e realizou-se o enceramento diagnóstico.Na prova estética (mock-up), todas as alterações sugeridas foramanalisadas. Após aprovação do tratamento proposto, realizaram-sepreparos dentários minimamente invasivos, seguindo da moldagemcom silicone de adição, escolha da cor e confecção de restauraçõesprovisórias. Posteriormente, foi realizada a prova dos laminados eprocedimentos necessários para a cimentação adesiva com cimentoresinoso fotoativado. Conclusões: A reabilitação com laminados cerâmicos,além de promover excelente resultado estético, proporcionouà paciente uma melhora na autoestima e aceitação social. Contudo,um correto planejamento e boa comunicação com o laboratório sãoprimordiais para o sucesso do tratamento.ABSTRACTThe presence of conoids lateral incisors demands a restorative aestheticapproach. Among the treatment options are the minimally invasiveceramic veneers. However, this restorative modality represents a majorchallenge, especially when referring to the anterior teeth of youngpatients. Objective: To report a case of harmonizing smile with lithiumdisilicate veneers. Case description: A female patient sought by dentalcare, reporting dissatisfaction with the diastema and the conoidslateral incisors restored with composite resin. It was planned rehabilitation,using ceramic veneers in units 13 to 23. Previously, the studycasts were obtained, and the diagnostic waxing was performed. In theaesthetic proof (mock-up test), all proposed changes were analyzed.After approval of the proposed treatment, minimally invasive dentalpreparations were performed, followed by a mold of silicone addiction,choose the color and manufacturing of the provisional veneers.In the next consult, were carried out the pieces and it was carried outthe necessary procedures for the adhesive cementation. Conclusions:Rehabilitation with ceramic veneers, besides allowing excellent aestheticresults, provided the patient an improved in self-esteem andbetter social acceptance. However, a good planning and a good communicationwith the laboratory are extremely important for successfultreatment.
ETILOGIA DAS FISSURAS LABIOPALATINAS: REVISÃO DE LITERATURA CLEFT LIP AND PALATE ETHIOLOGY: LITERATURE REVIEW
Authors: Viana Mariana Vitória Gomes , Cerqueira Júlia Santos , Bittencourt Marcos Alan Vieira , Barbosa Inêssa da Silva
Published: March 2022

As fissuras labiopalatinas (FLP) são as anomalias craniofaciais de origemembrionária com maior prevalência, acometendo cerca de 2 a 3% dosrecém-nascidos, de etiologia multifatorial, que envolve predisposiçãogenética e exposição a fatores teratogênicos. O objetivo do presentetrabalho é, através de uma revisão da literatura, contribuir para o maiorconhecimento sobre os fatores etiológicos envolvidos nessa má-formação.Realizou-se uma busca nos bancos de dados PubMed, ScienceDirect e Lilacs, alem de referencias cruzadas com os artigos científicospesquisados. Foram selecionados 18 artigos, utilizando como critériosde seleção o ano de publicação, posterior a 2010, e relevância para atemática. Houve um consenso na literatura consultada quanto à multifatoriedadee quanto ao período de risco de desenvolvimento da FLP,os primeiros três meses de VIU, frente aos agentes etiológicos da máformação, sendo o uso de fumo e álcool, a exposição a radiações ionizantese agentes infecciosos e a carência nutricional os fatores ambientaismais citados. A literatura, no entanto, não apresenta consensoacerca da importância de cada um desses fatores. Conclusão: Desdeo nascimento, o indivíduo convive com a deficiência em processosfisiológicos básicos, tais como sucção, mastigação e fonação, o quegera um comprometimento nutricional, estético e psicológico, o quedenota a necessidade de estudos adicionais a respeito da etiologia.ABSTRACTCleft lip and/or palate (CLP) are the most prevalent craniofacial anomaliesof embriologic origin, affecting about 2 to 3% of the newborns,with a multifactorial etiology, involving genetic predisposition and exposureto teratogenic factors. Literature, however, does not provideconsensus on the importance of each of these factors. The objective ofthe present study is, through literature review, contribute to the greaterknowledge about the etiological factors involved in this malformation.It was conducted a search on PubMed, Science Direct and Lilacs databases,in addition to cross-references of scientific papers researched.We selected 18 articles, using as selection criteria: year of publication,after 2010, and relevance to the theme. There was a consensus in theliterature consulted regarding the multifactorial and the period of riskof developing the CLP, the first three months of IUL, against the etiologicalagents of malformation, being the use of cigarettes and alcohol,exposure to ionizing radiation and infectious agents and the nutritionaldeficiency the most cited environmental factors. Since birth, theindividual coexists with deficiency in basic physiological processes,such as sucking, chewing and phonation, which causes a nutritional,aesthetic and psychological impairment, which indicates the need foradditional studies on etiology.
APLICAÇÃO DIAGNÓSTICA DE IMAGENS TRIDIMENSIONAIS (3D) NA DOENÇA PERIODONTAL DIAGNOSTIC APPLICATION OF THREE-DIMENSIONAL IMAGES (3D) IN PERIODONTAL DISEASE
Authors: Gomes Viana Mariana Vitória , Cerqueira Júlia Santos , Seixas Pinto Regina Lucia
Published: March 2022

A doença periodontal é uma doença altamente prevalente na populaçãomundial e se caracteriza pela destruição progressiva do ligamento periodontale reabsorção da crista óssea alveolar interdental e interradicular. Temcomo fatores etiológicos as bactérias do biofilme que associadas aos fatoresgenéticos e ambientais geram uma resposta inflamatória liberam enzimasproteolíticas e danificam o tecido de suporte dental. A avaliação da perdada inserção periodontal por exame clínico é limitada pelos instrumentosde sondagem e condições anatômicas, portanto, imagens radiográficas sãoinevitáveis para determinar a extensão e a gravidade das lesões, pois a representaçãoespacial do osso alveolar tem um valr altamente significativona Periodontia, uma vez que as decisões terapêuticas e as estimativas a longoprazo do prognóstico se fundamentam nele. O exame de imagem maiscomumente utilizado é através de radiografias convencionais, no entantofornece apenas uma visão bidimensional das estruturas tridimensionais,perdendo assim o valor diagnóstico essencial. A imagem tridimensional ou3D, tem se revelado como uma ferramenta clínica, pelo valor altamente informativo.O objetivo do presente trabalho consiste em realizar uma revisãode literatura sobre a aplicação diagnóstica da tomografia computadorizadade feixe cônico em lesões periodontais. Periodontal disease is characterized by the progressive destruction of theperiodontal ligament and alveolar bone Crest resorption interdentallyand interradicular, its etiological factors that biofilm bacteria associatedwith genetic and environmental factors generate an inflammatory responsethat release proteolytic enzymes and damage the fabric of dental support. The evaluation of periodontal insertion loss by clinical examinationis limited by probing instruments and anatomical conditions, therefore,x-rays are inevitable to determine the extent and severity of injuries,because the space representation of the alveolar bone has a significantrole in Periodontics, since therapeutic decisions and long-term estimatesof prognosis are based on it. The most commonly used imaging methodis through conventional x-rays, however, provides only a two-dimensionalview of the three-dimensional structures, thereby losing the essentialdiagnostic value. 3D image has proved as a clinical tool for highly informativevalue. The purpose of this study is to conduct a review of the literatureabout the intended use of cone beam computed tomography inperiodontal lesions.
Thermoelectric Module of SiGe Bulk Alloys Forming p‐n Junction at the Hot Side
Authors: Fujimoto Shinichi , Nagase Kazuo , Ohshima Hironori , Murata Masayuki , Yamamoto Atsushi , Lee Chul Ho
Published: March 2022

Thermoelectric power generation is a potential technology for providing green energy. It is expected to be able to convert enormous amounts of waste heat to electrical energy. To realize this technology, further increases in conversion efficiency and durability are essential. In particular, durability is a critical issue, especially for harnessing high‐temperature heat sources. Thus, a thermoelectric module of SiGe is fabricated without electrodes at the hot side, which is the main cause of aging. Electronic conduction betweenp‐ and n‐type elements is alternatively introduced using a direct connection, forming ap‐n junction. Sufficiently low electrical contact resistances are achieved at thep‐n junction above 300 °C due to the dissipation of the depletion layer. The conversion efficiency is 2.0% with a hot‐side temperature of 700 °C. The power‐generation performance is constant during heat‐run tests conducted at 700 and 500 °C under vacuum and air, respectively, for more than 450 h. The results demonstrate that a stable power‐generation technology using a thermoelectric module at high temperatures is established successfully.
A Highly Conducting Polymer for Self‐Healable, Printable, and Stretchable Organic Electrochemical Transistor Arrays and Near Hysteresis‐Free Soft Tactile Sensors
Authors: Su Xiaoqian , Wu Xihu , Chen Shuai , Nedumaran Anu Maashaa , Stephen Meera , Hou Kunqi , Czarny Bertrand , Leong Wei Lin
Published: March 2022

A stretchable and self‐healable conductive material with high conductivity is critical to high‐performance wearable electronics and integrated devices for applications where large mechanical deformation is involved. While there has been great progress in developing stretchable and self‐healable conducting materials, it remains challenging to concurrently maintain and recover such functionalities before and after healing. Here, a highly stretchable and autonomic self‐healable conducting film consisting of a conducting polymer (poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate), PEDOT:PSS) and a soft‐polymer (poly(2‐acrylamido‐2‐methyl‐1‐propanesulfonic acid), PAAMPSA) is reported. The optimal film exhibits outstanding stretchability as high as 630% and high electrical conductivity of 320 S cm−1, while possessing the ability to repair both mechanical and electrical breakdowns when undergoing severe damage at ambient conditions. This polymer composite film is further utilized in a tactile sensor, which exhibits good pressure sensitivity of 164.5 kPa−1, near hysteresis‐free, an ultrafast response time of 19 ms, and excellent endurance over 1500 consecutive presses. Additionally, an integrated 5 × 4 stretchable and self‐healable organic electrochemical transistor (OECT) array with great device performance is successfully demonstrated. The developed stretchable and autonomic self‐healable conducting film significantly increases the practicality and shelf life of wearable electronics, which in turn, reduces maintenance costs and build‐up of electronic waste.