bluuebunny/crossref_metadata_2025 huggingface dataset:
A CARVED FIGURE OF SAINT DEMETRIUS OF THESSALONICA IN THE EPONYMOUS AISLE OF THE ASSUMPTION CATHEDRAL OF THE MOSCOW KREMLIN. THE RELIC AND ITS SCULPTURAL EMBODIMENTY
Authors: Ryndina Anna V.
Published: June 2023

In the article, the author continues her research on the Holy relics and wooden carved sculpture in ancient Russian art in the context of East and West relations.
The author draws attention to the current problem of studying the relationship of form formation with the structure of symbolic thinking within the cultural space of the era. Moreover, the author explores historical analytical texts which highlight the problems of sacred synthesis, confirming the author’s conclusions that church space and each object, regardless of its size and sacred significance, originally formed a single whole.
In her article, the author proves that the kiot carved statue of St. Demetrius of Thessalonica was made by a Moscow master at the end of the 14th — beginning of the 15th centuries. It was placed in the Demetrius chapel of the Assumption Cathedral of the Moscow Kremlin, signifying, according to Metropolitan Cyprian’s plan, the image of the saint’s “tomb board”, which was brought to Vladimir from Thessalonica in 1197. Restored in the 16th and 17th centuries, the icon of the Thessalonica martyr, from which a golden filigree crown (the end of the 14th — beginning of the 15th century) has been preserved, could have also been commissioned by Cyprian in order to liken the Moscow Assumption Cathedral to the ancient basilica of St. Demetrius, and Moscow to Thessalonica. The only ancient shrine brought to Moscow from Vladimir in the 90s of the 14th century was most likely a Byzantine ark of the 11th century with a particle of St. Demetrius’s “shirt”, which was the main shrine of the basilica. The reconstruction of the “tomb board”, commissioned by Cyprian, in the form of a wooden statue of the saint confirms the opinion that it was a relief.
The author draws attention to the polemical problem of interpretation of the phenomenon of Russian church sculpture in the synodal era as a manifestation of pagan beliefs, pointing out that its in-depth study at the end of the 20th — beginning of the 21st centuries made it possible to assert the high spiritual and artistic status of this phenomenon. The author bases her evidence on archival documents, analysis of historical and cultural contexts, and comparative analysis of monuments.
ART AND HISTORY OF BYZANTIUM IN THE WORK OF ARTIST-JEWELLER EDUARD NIKITIN
Authors: Simakina Polina V.
Published: June 2023

The article is devoted to the work of Moscow artist Eduard Nikitin in the context of Byzantine decorative and applied heritage. Eduard Nikitin was born in Chelyabinsk and was educated as a sculptor. He worked as the chief artist at a factory for the production of art products in Chelyabinsk; afterwards, he became an independent jewellery artist. In modern author’s jewellery, the artist-jeweller rethinks the history of Byzantium, creates jewellery in the Art Deco style, basing on the impressions of Byzantine art. The author has always been attracted by the combination of the East and the West, common features and differences that can be expressed in jewellery plastic art. Eduard Nikitin had lived for two years in Finland and worked for Archbishop Johannes. He created a landmark work, The Fall of Constantinople, which is a rethinking of the fall of a great empire. It is worth paying attention to the set of a brooch and earrings, Evening in Byzantium, where the golden parts represent Hagia Sophia and the central blue topaz - the Bosphorus, as a connection between Europe and Asia. The combination of artistic images of monuments presents the organic syncretism of the entire outlined Asiatic region art. This region’s art was born in the regularity of society’s life and its spiritual culture on the basis of reality. The article compares samples of Byzantine art from museum collections with the works of Eduard Nikitin; the author’s views on his own jewellery work are given. In striving for the possible accuracy in the attribution of a work of art, one should not be confined to the era of its creation. Its content and form are often rooted in the distant past. As a result of a long and complex development, a “layered” semantic and artistic structure of the work appears. The fullness of this or that plot is revealed only in the “long time”, during which it is enriched with new meanings. Owing to the author’s interview, there is a synthesis of an artist and a researcher, which is valuable for the analysis of contemporary works. The features of Byzantine art are considered in the context of influence on contemporary artists; the features of the technology for creating jewellery as well as to what extent they are borrowed in modern times and replaced by new technologies are analysed. The main purpose of the article is to show the diversity of Russian contemporary art using the example of one artist.
THE LATEST PRACTICES IN MOTION GRAPHICS DISPLAY: THE DEMO DESIGN IN MOTION FESTIVAL
Authors: Sokolova Liubov M.
Published: June 2023

The formation of digital trends in both art and design is due to the development and ubiquity of computer technology. In graphic design, new technologies influence not only design methods but also the emergence of new synthetic genres such as motion design in many ways. This article highlights the use of motion graphics in various visual areas on the example of the well-known design project of the Dumbar/DEPT® studio - the DEMO Design in Motion Festival. Today, in graphic design, there is an ever-increasing need to use motion graphics tools: from individual animated project elements to flexible, dynamic identica. It is due to the widespread transition of most information carriers to the digital environment. An animated image is more informationally saturated and is able to more actively attract the viewer through movement, which is especially important in the context of modern informational redundancy of the surrounding space. The big advantage of an animated image is its easy updating. Thus, the image can be easily broadcast on different screens or planes, thereby easier to fit into the modern urban space, and also, it does not require printing costs. The number of possible colours in a screen image is in the millions, and the ease of producing it with a camera or a phone is incomparable to printing processes. Particular attention is paid to the role of motion graphics in the modern digital space. Computer technologies give a designer not only a tool for designing but also create a new digital environment for their work. However, researchers still face the problem of a single form and technological basis for storing digital images. International festivals act as platforms for discussing modern trends in design, as well as selecting and exhibiting the most innovative projects. Due to the transition of many design processes to the digital environment, today it is becoming more and more important to have a platform for placing screen works. In 2019, the DEMO Design in Motion festival became such a platform. Founded by Rotterdam-based studio Dumbar/DEPT®, the festival is by far the largest motion graphics exhibit platform.
Iterative Excision in the Surgical Treatment of Scar Areas in Marrakech: About 33 Cases
Authors: Opango A. D. C. , Fettal F. , Hadri H. El , Boukhani M. , Aziz Z. , Hattab N. Mansouri-
Published: June 2023

Summary: The scarred areas pose the problem of their management. Aim: Show the importance of iterative excisions in the surgical management of scarred areas. This paper presents a prospective study carried out during a humanitarian campaign within the maxillofacial surgery department of the CHU Mohammed VI on the management of scars, during which we identified 33 cases of scarred areas treated by iterative excision. The sample was predominantly male, with a sex ratio of 2.3 and an average age of 26.9 years (extremes 6 – 58 years). Scarred areas were secondary to self-mutilation in 54.5% of cases and were located on the forearms in 36.7% of cases. All patients underwent iterative excision using spindle or W-shaped excision, with favorable outcomes. Iterative excision is a proven surgical procedure in the management of giant nevi. Here, we demonstrate the contribution of this technique in the management of scarred areas.
Amoebic Liver Abscess Associated with Viral Hepatitis C in an Elderly Patient
Authors: Saliou Mahamadou , Boly Berthe Bréhima , Nagou Tolo , Mamane Toure , Karim Dao , Mamadou Togo , Drissa Sangare , Nanko Doumbia , Amadou Dembele Ibrahima , Mamadou Cissoko , Kaly Keita , Abdramane Traore , D Camara Boua , Salimata Diallo , Kadiatou Doumbia , M Cisse Sékou , Djibril SY , Djénébou Traore , Kaya Soukho Assétou
Published: June 2023

Introduction: Amebic liver abscess is a suppurative collection of parasitic origin. The causative organism is usually the ubiquitous Entamoeba histolytica. In Mali, a study reported a hospital incidence rate of 2.4%. Radiological exploration of the liver has made a major contribution to improving early diagnosis and management. Treatment involves metronidazole and evacuation of the suppurative collection. We report the case of a 71-year-old patient who developed an amebic liver abscess associated to viral hepatitis C with a very high viral load. The diagnosis was made on the basis of clinical, biological and radiological signs, amoebic serology and the characteristic of the pus. Antiparasitic treatment, drainage of the abscess and antiviral treatment resulted in a good clinical outcome. The epidemiological, diagnostic and therapeutic characteristics of amebic abscesses are discussed. Conclusion: Hepatic amebiasis is common. Diagnosis is guided by the FONTAN triad, biology and imaging. The chocolate-coloured characteristic of the pus and the serology confirm the diagnosis. Treatment is medical and instrumental (ultrasound-guided). Association with hepatitis C infection appears to be rare.
Post-Traumatic Complete Paralysis of the III Pair of Cranial Nerves at Sikasso Hospital: A Case Report
Authors: Oumar Diallo , Sidibé Moro , Diallo Salimata , Cisse Mohamed El Hassimi , Koita Kadiatou Ba , Coulibaly Brainima , Sidibé Mohamed Kole , Traore Fatoumata , Coulibaly Yacouba , Dembélé Adama , Diarra Mamadou , Togo Mamadou Adama , Coulibaly Abdoulaye Nouhoum , Goita Daouda , Théra Japhet Pobanou , Traore Lamine , Traore Jeannette , N’Diaye Fatoumata , Keita Chaka
Published: June 2023

Public road accidents (AVP) are frequent and serious and are responsible for numerous cranioencephalic and neurological lesions. Paralyzes of the oculomotor nerves are frequently reported, especially in young subjects during these AVPs. We report the case of complete paralysis of the third pair of cranial nerves in a 22-year-old young lady, following a road accident. Clinical examination revealed intrinsic and extrinsic paralysis of the 3rd pair of cranial nerves. Computed tomography showed a subarachnoid hemorrhage. After 7 days of hospitalization under analgesics and hyperhydration, a complete regression of the lesions was obtained. An angio-scan performed 3 months after the accident showed a slight non-significant stenosis of 25. 54% of the left internal carotid without anomaly of the intracranial vascular network. Paralyzes of the third cranial pair, total or partial, most often regress within variable periods of 6 months to 2 years. The prevention of accidents on the public highway requires the application of road safety measures.
Cantrell Pentalogy Associating Acrania and Iniencephaly: Antenatal Ultrasound Diagnosis at the CHU Pr BSS of Kati
Authors: Guindo Ilias , Mamadou N’diaye , Ousmane Traore , Issa Diarra , Joseph Kamissoko Mady , Abdoulaye Sissoko , Ouncoumba Diarra , Lassine Keita , Moussa Fomba , Salia Coulibaly
Published: June 2023

Introduction: Cantrell's pentalogy is a rare malformation, which associates 5 cardinal malformations: supraumbilical hernia of the abdominal wall, defect of the anterior part of the diaphragm and diaphragmatic pericardium, abnormality of the lower part of the sternum, heart defects. Ultrasound is essential in antenatal diagnosis. We report a case of polymaformative syndrome, including Cantrell pentalogy, acrania and iniencephaly. Observations: Mrs. BS, 24 years old, housewife, resident in rural areas, 3rd pregnancy, two live children, no medical-surgical history or known fetal malformation, no notion of teratogenic drug intake. Coming for his first ultrasound, which, performed by two radiologists concluded to a polyformative syndrome associating cantrell pentalogy, acrânie and iniencephaly: by the presence of a defect of closure of the anterior thoraco-abdominal wall resulting in an evisceration of the intra-abdominal organs, a cardiac malformation, the absence of formation of the bones of the skull, and absence of cervico-occipital bone formation with neck shortening and hyper extension of the head. The pregnancy was estimated at 27 weeks, the couple was informed of the fate of the future baby and the pregnancy intervention was proposed. After their agreement the labor was triggered, after 8 hours, she expelled a live newborn male, polymalformed confirming the ultrasound diagnosis, weighing 1900grams and lived only thirty minutes after birth. Conclusion: The polymalformative syndrome associating cantrell pentalogy, acrania and iniencepahlia is exceptional. Ultrasound is essential in diagnosis. Termination of pregnancy is the rule.
Spontaneous Spinal Epidural Hematoma in an Infant: A Case Report
Authors: Hadri K. El , Ahmanna H. C. , Zouita B. , Basraoui D. , Jalal H.
Published: June 2023

A spontaneous spinal epidural hematoma (SSEH) is an uncommon but severe condition with a high morbidity rate, especially in infants. It results from an accumulation of blood in the spinal epidural space. It requires early diagnosis and urgent management to achieve recovery of neurologic function. It refers to a non-traumatic etiology and excludes other possible causes such as hemophilia, neoplasms, arteriovenous malformation, coagulopathies, and iatrogenic causes. The clinical features are often nonspecific, leading to a delay in diagnosis. MRI provides the most valuable visualization of the location and hematoma mass as well as the presence of the spinal cord compression. SSEH can occur in any spinal cord segment but predominantly at the posterior cervicothoracic and thoracolumbar levels. The source of hemorrhage SSEH can be both vertebral venous plexus system and arterial source. We report a rare case of an infant spontaneous spinal epidural hematoma whose diagnosis was delayed because of a recent history of angina before his development of neurologic deficits. Magnetic resonance imaging of the spine revealed a dorsal spinal epidural hematoma with compression extending from C7 to T3 a. There were no predisposing factors. Laminectomy of C7 and the first three dorsal vertebrae and complete evacuation of hematoma was done.
Osteochondral Lesion of the Talus Dome: What's New in the Therapeutic Protocol
Authors: Abakka Mehdi , Baidriss Y. , Ouagari H. El , Mekkaoui MJ , Bouffetal M. , Bassir RA , Kharmaze M. , Lamrani MO , Berrada MS
Published: June 2023

Osteochondral lesions of the talus must be known, and especially in the aftermath of hindfoot trauma. Even if certain mechanisms producing them are known, their etiopathogenesis is not yet formally settled. It seems essential, to characterize them, to use the radiological classification fracture-osteonecrosis-geod (FOG). Their diagnosis, like their surgical treatment, remains always a challenge for the practician: certain rules are common to all, such as debridement and abrasion of necrotic tissue, others optional depending on habits, situation and size of lesion. None of them seem superior to the others. Arthroscopy was required for lesions of modest size less than 1.5 cm2, while the others must be filled. The support of these lesions therefore always remain delicate and relatively us to certain modesty about _the literature also encouragesthe results of surgical management.
Vogt-Koyanagi-Harada Disease Diagnosed in a Black-Skinned Woman in Internal Medicine
Authors: Kaly Keïta , Drissa Sangaré , Nagou Tolo , Boly Berthé Brehima , Nanko Doumbia , Mamadou Togo , Dembélé Dembélé Ibrahima , Maїmouna Togo , Mahamadou Bengaly , Sirandou Sissoko , Yamoussa Karabinta , Djibril Sy , Djénébou Traoré , Kaya Soukho Assétou , Kader Traoré Abdel , Alassane Traoré Hamar
Published: June 2023

Introduction: Vogt-Koyanagi-Harada disease, initially described as an uveomeningoencephalitic syndrome, is a systemic granulomatous autoimmune disease that targets melanocyte-rich tissues, such as the eye, inner ear, meninges, skin and hair. It is one of the most prevalent causes of noninfectious uveitis affecting, more frequently, individuals of pigmented skin, such as Asians, Middle Easterners, Hispanics and Native Americans. However, it is very infrequent among persons of African descent. Here, we report on a case in a black-skinned woman in internal medicine. Clinical Observation: A 45-year-old Malian black-skinned woman with no history of ocular trauma or intraocular surgery presented at internal medicine outpatient clinic with 3-months history of achromic skin patches over the face and trunk, bilateral visual disturbance, bilateral hearing loss with tinnitus and headache. Dermatological examination revealed bilateral, symmetrical achromic lesions over the back, buttocks and eyelids, with scalp poliosis; and perioral pityriasis versicolor lesions. She had no alopecia or other dermatological lesions. Ophthalmological examination revealed a profound drop in visual acuity. Oto-rhino-laringologic examination revealed a discreet hearing loss. Ophthalmological investigations revealed bilateral posterior panuveitis on funduscopic examination, bilateral chronic iridocyclitis on slit- lamp examination, and bilateral choroidal thickening on ocular ultrasound. The diagnosis of Vogt-Koyanagi-Harada was retained, based on the diagnostic criteria established by the American Society for the Study of Uveitis (UAS) in 1978. Prednisone at a dose of 1.5 mg per kilogram tapering courses with adjuvant treatment was initiated. The ophthalmologist's prescription consisted of 1% atropine eye drops, 0.25% timoptol eye drops and dexamethasone eye drops which had been discontinued because of systemic cortitherapy; and that of the dermatologist, Hydrocortisone butyrate 0.1% cream, .......
The Hyper-Reactive Malarial Splenomegaly- A Rare and Severe Form of Chronic Plasmodial Infection: About A Case
Authors: Kaly Keïta , Drissa Sangaré , Boly Berthé Brehima , Nagou Tolo , Mamadou Togo , Mamadou Mallé , Mamadou Traoré Abdoulaye , Garan Dabo , Djibril Sy , Djénébou Traoré , Kade Traoré Abdel , Kaya Soukho Assétou , Kassim Minta Daouda , Alassane Traoré Hamar
Published: June 2023

Introduction: Hyper-reactive malarial splenomegaly is a leading cause of large tropical splenomegaly in endemic zones. Here, we report a case diagnosed in a young woman living in Guinea, a malaria-endemic area. Clinical observation: A 32-year-old Guinean woman with a history of repetitive malaria infection episodes presented to the internal medicine outpatient clinic with 5-months history of voluminous mass of the left flank extending to the umbilical region, with no pain and progressive onset, and a sensation of early satiety accompanied by eructation and epigastralgia worsened with eating. Digestive examination revealed a large, firm, smooth-surfaced, painless splenomegaly with a splenic size 20 centimeters below the left costal margin on the mid-clavicular line and measuring 28 centimeters in its long axis. The initial complete blood count showed a normocytic normochromic anemia with lymphocytosis, neutropenia and thrombocytopenia. The erythrocyte sedimentation rate (ESR) was 65 mm at the first hour. Malaria rapid diagnostic test (RDT) was positive for Plasmodium. The thick blood smear had come back negative. Serum protein electrophoresis demonstrated a decrease in albumin to 36.5 g/l and an increase in gamma globulins to 19.1 g/l. Immunoelectrophoresis of serum proteins showed a polyclonal increase in IgG. Abdominal ultrasound revealed enormous homogeneous splenomegaly (180 millimeters). The diagnosis of Hyper-reactive malarial splenomegaly was made on the basis of diagnostic criteria established by Fakunle et al in 1981. Our patient presented with enlarged splenomegaly, negative thick smear, positive RDT for plasmodium, elevated erythrocyte sedimentation rate, lymphocytosis, pancytopenia, and a good therapeutic response. Atovaquone-proguanil 250mg/100 mg at a dose of 1000mg/400 mg, i.e. 4 tablets taken as a single dose over three days, was initiated, then relayed by alternance of doxycycline 100 mg (100 mg once daily) for 1 month and nivaquine 100 mg ..........
Long Term Use of Benzodiazepines and Delayed Awakeness from General Anesthesia: A Case Report
Authors: Yoo Kookhyun , Kim Minguan , Hwang Sung Mi
Published: June 2023

We present two delayed awaken cases that underwent general anesthesia and showed altered mentality with unresponsiveness in the postanesthesia care unit (PACU) after successful extubation in the operating room. Both patients had been taking benzodiazepines chronically before surgery. In case 1, extubation was carried out without any problems and arrived at the PACU. After 15 minutes, she suddenly developed hyperventilation, shivering, and a state of consciousness that does not respond to verbal command. Eyes were kept closed and she showed decreased pain withdrawal response in all extremities. After 90 minutes at PACU, she was able to obey simple verbal instructions. All symptoms showed gradual improvement within 5-6 hours. In case 2, 20 minutes after transferal to PACU, the patient showed drowsy mentality with no response to verbal or pain stimuli. Altered mental state lasted 3 days and motor weakness of extremities lasted 5 days. Brain MRI and other examinations showed no abnormalities. They were discharged without any neurological complications.
Pengaruh Kepemilikan Manajerial, Leverage, dan Profitabilitas Terhadap Tax Avoidance pada Perusahaan Manufaktur
Authors: Situmorang Bornok , Anastasia Vivian
Published: June 2023

This study aims to determine the effect of managerial ownership, leverage, and profitability on tax avoidance of the manufacturing companies listed on Indonesia Stock Exchange (IDX) from 2016-2019. The sample selection in this study uses a purposive sampling technique. This research is a quantitative research with secondary data. The data analysis technique uses multiple linear regression analysis with the help of SPSS (Statistical Product and Service Solution) software version 22. The results of the research partially show that managerial ownership has no significant effect on tax avoidance, leverage has no significant effect on tax avoidance, and profitability has significant effect on tax avoidance. Simultaneous research results indicate that managerial ownership, leverage, and profitability together have a significant effect on tax avoidance.
STUDI IN SILICO PEMBENTUKAN KOKRISTAL MELOXICAM DENGAN BERBAGAI KOFORMER PERBANDINGAN (1 : 1)
Authors:   Program Studi S1 Farmasi, Fakultas Kedokteran, Universitas Hang Tuah Surabaya, Najih Yuli Ainun , Izazi Farizah , Siswandono Siswandono ,   Fakultas Farmasi, Universitas Airlangga Surabaya, Putri Bella Anggraini
Published: June 2023

Cocrystal is one form of modification in increasing the solubility of meloxicam which is included in Biopharmaceutics Classifications System (BCS) II. Cocrystal is a multicomponent system with a stoichiometric ratio between the active ingredient and the coformer which are bound in the crystals lattice to form hydrogen bonds. Design of new drugs can be done through an in silico program to optimize the parent compound before the synthesis of derivative compounds. This study aims to predict which coformers are most stable in the formation of crystals. Cocrystal formation is done by drawing a two-dimensional structure from meloxicam and coformer using ChemBioDraw Professional 16.0 software from CambridgeSoft®. The prediction will result in the amount of bond energy formed between meloxicam with coformer. The smaller the bond energy, the more stable the meaning of the bond. The smaller the bond energy formed, the more stable the bond is. Stable bonds have a high probability of forming cocrystals meloxicam. Hydrogen bonds occur between hydrogen atoms and other atoms that have high electronegativities such as O and N atoms which have lone pairs of electrons. This electronegativity difference makes H atoms tightly bound to O and N atoms so that the hydrogen bonds in the meloxicam cocrystal are tightly bound and stable. From the results of the study showed that the most stable coformer can form cocrystals with a small bond energy that can produce bonds with meloxicam, namely urea.
AKTIVITAS ANTIHIPERTENSI EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R.Forst. & G.Forst.) PADA MODEL HEWAN HIPERTENSI YANG DIINDUKSI PREDNISON DAN NaCl
Authors:   Program Studi S1 Farmasi, Universitas Bhakti Kencana, Lestari Kharina Septi , Susilawati Elis , Istiqomah Aulia Nurfazri , Amalia Silvi Nur , Aligita Widhya
Published: June 2023

Hypertension is a disease without symptoms that is very dangerous (silent killer) because it is often not realized. Conditions that are not controlled and occur continuously will cause a disease factor related to cardiovascular disease. Empirically, matoa leaves are commonly used as antihypertensive drugs. This study aims to determine the activity of the ethanolic extract of matoa leaves as a diuretic and antihypertensive. Diuretic testing was carried out for 6 hours with urine volume measurement every hour. Each test animal was given warm water as a loading dose, using a comparison (Furosemide 3.6 mg/KgBW) and the matoa leaf ethanol extract test group with doses of 150, 300, and 500 mg/KgBW. Antihypertensive testing was carried out in a preventive manner using Prednisone 1.5 mg/KgBW and NaCl 2%, comparison (Hydrochlorothiazide 2.25 mg/KgBW) and the test group ethanol extract of matoa leaves with doses of 150, 300, and 500 mg/KgBW. given orally for 14 days. The test parameters were urine volume, systolic blood pressure and diastolic pressure. The data obtained were analyzed using One Way ANOVA and Kruskall Wallis. The results showed that the ethanol extract of matoa leaves could increase urine output, and decrease systolic and diastolic blood pressure because it had a comparable activity with the comparison group (p<0.05). A dose of 150 mg/kgBW has the most effective activity as an antihypertensive.
LETHAL CONCENTRATION OF Saussurea costus WITH BRINE SHRIMP LETHALITY TEST METHOD
Authors:   Pharmacology and Clinical Pharmacy Department, Medical Faculty, UPN Veteran Jakarta, Pradana Dhigna Luthfiyani Citra , Yusmaini Hany ,   Pharmacology Department, Medical Faculty, UPN Veteran Jakarta, Harfiani Erna ,   Pharmacology Department, Medical Faculty, UPN Veteran Jakarta
Published: June 2023

The safety of using herbal plant extracts is essential for COVID-19 patients who consume herbal plants daily to increase immunity and overcome the symptoms of the disease. One of the herbal plants used by the community in COVID-19 therapy is Qusthul Hindi (Saussurea costus). The public needs to know the safety of these herbal remedies when consuming them. Therefore it is essential to conduct a toxicity test of Hindi Qusthul extract. Secondary metabolite compounds present in plant extracts can be tested for toxicity in vitro using the Brine shrimp lethality test (BSLT) method using Artemia salina Leach larvae to determine LC50 values. The BSLT method is used to determine biological activities in extract plants, such as cytotoxic activity, phototoxic, enzyme inhibition, and ion regulation, using Artemia salina Leach shrimp larvae as bioindicators. The BSLT method is carried out by observing the mortality rate in Artemia salina Leach shrimp larvae which are given extracts from plants and then incubated for 1x24 hours. The results obtained from this study as an LC50 (Lethal concentration) value of 532.78 ppm. LC50 (Lethal Concentration) value of 532.78 ppm indicates that the concentration of the compound can cause death in Artemia salina Leach by as much as 50%.
EFEKTIVITAS PENYULUHAN PENGETAHUAN MENGENAI SKABIES PADA WALI SANTRI PONDOK PESANTREN DARUS SALAM TORJUN, SAMPANG
Authors:   Fakultas Kedokteran, Universitas Airlangga, Munif Muhammad Za'im , Utomo Garuda Nusantara Putra , Rossyanti Lynda ,   Departemen Parasitologi, Fakultas Kedokteran, Universitas Airlangga
Published: June 2023

Increased knowledge about scabies not only needed to be given to students at the schools, but also to the families for minimizing contact with their children whose suffering scabies when they return home. One way to increase knowledge about scabies among the students’ family is to provide them with counseling. The purpose of this study was to evaluate the effectiveness of counseling on scabies to the students’ family of the Pondok Pesantren Darus Salam Torjun, Sampang. This research is a quasi-experimental type with a one group pretest and posttest design which was carried out at Pondok Pesantren Darus Salam Torjun, Sampang on July 11, 2022 to August 1, 2022. 52 participants were obtained using purposive sampling. The research instrument used for this study was a questionnaire containing 15 valid and reliable questions about scabies. The statistical test used was the Wilcoxon test because the pretest and posttest data were not normally distributed. The results of statistical tests showed that there was a difference between the results of the pretest and posttest (p=0.000). The conclusion of this study is that counseling about scabies to the students’ family of the Pondok Pesantren Darus Salam Torjun, Sampang showed effective results.
CARACTERIZAÇÃO TECNOLÓGICA EM QUARTZITOS TRATADOS COM HIDRORREPELENTES
Authors: Garcia Carlos Henrique Wingler , Freitas Lilian Gabriella Batista Gonçalves de
Published: June 2023

As rochas compõem a maior parte do nosso planeta, apresentando composições variadas, com textura e estruturas bem definidas, algumas, devido padrão estético, são usadas como revestimento na construção civil. A água é o maior agente intempérico das rochas ornamentais, e está presente em todos os ambientes, quando em contato com as rochas, causa grandes prejuízos estéticos na construção civil. Em virtude das patologias oriundas da percolação da água nas rochas, este estudo avalia a eficácia na impermeabilização de amostras do quartzito, proveniente da região de Seabra na Bahia, denominado comercialmente como Kalahari, que tem grande índice de absorção de água. Busca-se avaliar a eficácia na impermeabilização com produtos protetivos hidrorrepelentes, a base de silano, comercializados no setor de rochas ornamentais. Para isso, foram consideradas as informações petrográficas como índices físicos, textura e estrutura, associados a métodos de aplicação por submersão com e sem auxílio de bomba a vácuo. Ao final do processo de impermeabilização das amostras, foram realizados ensaios de índices físicos novamente, para mensurar o processo de impermeabilização mais eficaz. Os resultados dos ensaios demonstram uma eficiência média de 45% na impermeabilização das amostras de rocha em apenas uma aplicação, o que é bastante representativo. Quanto ao ensaio usando método a vácuo a diferença foi de 10% a mais de absorção. Como o processo de impermeabilização por submersão é mais prático ele se mostrou mais interessante para uso industrial, porém através do uso de bomba a vácuo pode ser possível reduzir o tempo de tratamento mantendo a mesma eficácia.
Peran Kepuasan Dan Loyalitas Nasabah Dari Sudut Pandang Lokasi, Promosi, Dan Kualitas Pelayanan Pada Unit Pengelola Kegiatan Dana Amanah Pemberdayaan Masyarakat (UPK DAPM) Kabupaten Sragen
Authors: Hartawan Hartawan , Prastyowicaksono Dedy
Published: June 2023

Tujuan dari penelitian ini untuk menganalisis dan memberikan bukti secara empiris pengaruh Lokasi, Promosi, dan Kualitas Pelayanan terhadap Loyalitas nasabah UPK DAPM Kabupaten Sragen melalui Kepuasan nasabah. Sampel  dalam penelitian ini sebanyak 100 nasabah UPK DAPM di Kabupaten Sragen dimana sampel diperoleh dengan menggunakan teknik pengambilan sampel yaitu accidental sampling. Analisis data yang dilakukan berupa uji validitas, uji reliabilitas, uji linieritas, uji analisis jalur, uji t, uji F, uji koefisien deteminasi (R2), dan uji korelasi. Hasil penelitian menunjukkan bahwa Lokasi berpengaruh positif dan signifikan terhadap Kepuasan Nasabah UPK DAPM Kabupaten Sragen. Promosi berpengaruh positif dan tidak signifikan terhadap Kepuasan Nasabah UPK DAPM Kabupaten Sragen. Kualitas Pelayanan berpengaruh positif dan signifikan terhadap Kepuasan Nasabah UPK DAPM Kabupaten Sragen. Lokasi berpengaruh positif dan tidak signifikan terhadap Loyalitas Nasabah UPK DAPM Kabupaten Sragen. Promosi berpengaruh positif dan signifikan terhadap Loyalitas Nasabah UPK DAPM Kabupaten Sragen. Kualitas Pelayanan berpengaruh negatif dan tidak signifikan terhadap Loyalitas Nasabah UPK DAPM Kabupaten Sragen. Kepuasan Nasabah berpengaruh positif dan signifikan terhadap Loyalitas Nasabah UPK DAPM Kabupaten Sragen. Secara bersama-sama variabel Lokasi, Promosi, Kualitas Pelayanan, dan Kepuasan Nasabah berpengaruh signifikan terhadap Loyalitas Nasabah UPK DAPM Kabupaten Sragen. Loyalitas Nasabah UPK DAPM Kabupaten Sragen dijelaskan oleh Lokasi, Promosi, dan Kualitas Pelayanan dengan Kepuasan Nasabah sebagai variabel intervening sebesar 74,0% dan sisanya sebesar 26,0% dijelaskan oleh variabel lain diluar model penelitian, misal variable Tingkat Bunga, Jangka Waktu, Denda , dan lain-lain. Kesimpulan analisis jalur pada penelitian ini menunjukkan bahwa peningkatan Lokasi efektif dilakukan melalui pengaruh tidak langsung, peningkatan Promosi efektif dilakukan melalui pengaruh langsung, dan peningkatan Kualitas Pelayanan lebih efektif dilakukan melalui pengaruh tidak langsung.
INVESTIGATION OF THE DYNAMIC PROPERTIES OF A CABLE-STAYED BRIDGE DEPENDING ON THE STIFFNESS PARAMETERS OF ITS LOAD-BEARING ELEMENTS
Authors: Степанов С.Д. , Богомолов А.Г.
Published: June 2023

Изучены основные динамические свойства вантовых мостовых сооружений и связанные с ними явления, опасные для их безотказной эксплуатации. Для анализа динамических характеристик мостового сооружения рассмотрены возможные изменения жесткостных параметров вант и балки жесткости. Расчетная модель апробирована на примере вантового пешеходного моста через проток реки Кан в Красноярском крае. Воздействие статических и динамических нагрузок на вантовое сооружение моделировалось в конечно-элементных программных комплексах Лира САПР и SCAD++. Рассмотрены пять основных форм колебаний. Представлены результаты компьютерного моделирования в виде таблиц и графиков.

We studied the main dynamic properties of cable-stayed bridge structures and related phenomena that are dangerous for their trouble-free operation. We considered possible changes in the stiffness parameters of the shrouds and the stiffness beam to analyze the dynamic characteristics of the bridge structure. The calculation model was tested on the example of a cable-stayed pedestrian bridge across the channel of the Kan River in the Krasnoyarsk Territory. The impact of static and dynamic loads on the cable-stayed structure was modeled in the finite element software complexes Lira CAD and SCAD++. Five main forms of oscillations are considered. The results of computer modeling are presented in the form of tables and graphs.
FORMATION OF THE ARCHITECTURAL AND URBAN PLANNING SPACE OF ECOPOSITIVE MULTIFUNCTIONAL CULTURAL AND ENTERTAINMENT COMPLEXES
Authors: Кузнецов П.Э. , Миронова И.А.
Published: June 2023

Обозначены основные проблемы современных городов, связанные с неблагоприятным воздействием селитебного техногенеза на окружающую среду. Выявлена важная градообразующая роль экопозитивных многофункциональных культурно-зрелищных комплексов, определяющих эмоциональный тонус города, его образность и выразительность, соответствующая дружелюбной экологической, устойчивой среде и снижающая риски техногенеза. Проведен анализ экопозитивного архитектурного проектирования современных многофункциональных культурно-зрелищных комплексов, способствующих формированию устойчивого архитектурно-градостроительного пространства, на основе двадцати двух уникальных примеров зарубежной и отечественной практики проектирования и строительства подобных сооружений. Определены основные принципы экопозитивных проектных решений такого типа зданий. Сформулирован вывод об особой актуальности экологического проектирования современных многофункциональных культурно-зрелищных комплексов с максимальным использованием всего спектра технологий, приемов, направленных на формирование здорового, комфортного и безопасного архитектурно-градостроительного пространства.

In this article we consider the main problems of modern cities related to the adverse impact of residential technogenesis on the environment. We reveal an important city-forming role of ecopositive multifunctional cultural and entertainment complexes, determining the emotional tone of the city, its imagery and expressiveness, corresponding to a friendly ecological, sustainable environment and reducing the risks of technogenesis. The analysis of ecopositive architectural design of modern multifunctional cultural and entertainment complexes is carried out on the basis of twenty-two unique examples of foreign and domestic practice of design and construction of similar structures. We determined the basic principles of ecopositive design solutions of this type of buildings. A conclusion has been formed that testifies to the special relevance at present of the ecological design of modern multifunctional cultural and entertainment complexes with the maximum use of the entire spectrum of technologies, techniques aimed at creating a healthy, comfortable and safe architectural and urban environment.
ALEITAMENTO MATERNO EM NEONATOS COM MALFORMAÇÕES CONGÊNITAS DO SISTEMA NERVOSO CENTRAL EM UM HOSPITAL REFERÊNCIA DO SISTEMA ÚNICO DE SAÚDE, BELÉM – PA
Authors: Valente Késia Prestes , Rodrigues Eva Lorena Jaques , Matos Priscila Pinho de
Published: June 2023

Objetivos: Identificar o tipo de aleitamento realizado por crianças com malformações congênitas do sistema nervoso central internadas em uma Unidade Neonatal do Sistema Único de Saúde. Métodos: Estudo descritivo, retrospectivo e de abordagem quantitativa realizado através da visualização de prontuários de pacientes internados em uma unidade neonatal com idade de zero a seis meses diagnosticados com malformações congênitas do sistema nervoso central, ambos os sexos, internadas entre os períodos de março de 2020 a março de 2022. Resultados: A maioria dos pacientes pertencia ao sexo feminino, eram do interior do estado, com diagnóstico prevalente de hidrocefalia, e o principal desfecho clínico foi o de alta. Grande parte apresentava antecedentes gestacionais satisfatórios, nascidos de parto cesárea e idade gestacional a termo. O peso foi considerado normal ou adequado para idade na maior parte dos pacientes, o aleitamento predominante foi o misto e a maioria das mães permaneciam integralmente no hospital. Conclusão: É necessário maior apoio à amamentação deste grupo de malformações, sobretudo em decorrência das condições clínicas do paciente e de possíveis inseguranças da mãe e família, além de maiores pesquisas acerca desta temática, haja vista que, apesar da relevância, poucos foram os estudos encontrados na literatura científica.
Lingkungan Kerja dan Kompetensi, Pengaruhnya Terhadap Kinerja Pegawai RSUD Kota Makassar; Motivasi Sebagai Variabel Intervening
Authors: Muin Sri Adrianti , Anwar Andi Farisnah , Suryani Ade Irma
Published: June 2023

Lingkungan kerja dan kompetensi juga motivasi pada RSUD Kota Makassar sangat penting. Karenanya, tujuan dalam penelitian adalah menjelaskan juga dampak dari keterkaitan variabel lingkungan kerja serta kompetensi ke kinerja pegawai melalui motivasi di RSUD Kota Makassar.

Metode penelitian yaitu metode kuantitatif. Besar responden adalah 86 responden yang terdiri dari pegawai ASN, kontrak dan sukarela yang berada di RSUD Kota Makassar. Analisis data dilakukan dengan analisis jalur menggunakan SmartPLS, dengan mengolah data primer dan hasil penyebaran kuesioner pada pegawai RSUD Kota Makassar. Temuan dalam kajian penelitian: (1) variabel lingkungan kerja dampaknya positif dan juga signifikan ke kinerja pegawai RSUD Kota Makassar, (2) variabel kompetensi berdampak positif, signifikan ke kinerja pegawai RSUD Kota Makassar. (3) Variabel motivasi berdampak positif signifikan ke kinerja pegawai RSUD Kota Makassar, (4) Variabel lingkungan kerja pengaruhnya positif  dan signifikan pada variabel motivasi, (5) Variabel kompetensi memiliki pengaruh yang positif, tidak signifikan pada kinerja pegawai RSUD Kota Makassar, (6) Variabel Lingkungan kerja yang melalui motivasi memiliki pengaruh positif juga tidak signifikan ke kinerja pegawai RSUD Kota Makassar, dan (7) Variabel kompetensi yang melalui motivasi memiliki pengaruh positif tetapi tidak signifikan pada kinerja pegawai RSUD Kota Makassar.
Pengaruh Viral Marketing, Media Pemasaran Online, Kepercayaan Pelanggan Terhadap Keputusan Pembelian Tiktokshop
Authors: Sarpiana Sarpiana , Maszudi Edi , Hamid Rahmad Solling , Dewintari Putri , Wardani Kia Putri
Published: June 2023

Media sosial merupakan teknologi digital yang dibuat untuk memudahkan manusia dalam melakukan aktifitasnya, meskipun awalnya media sosial hanya digunakan sebagai alat bertukar informasi dengan keluarga maupun kerabat. Seiring perkembangan zaman media sosial dimanfaatkan oleh perusahaan besar maupun kecil untuk kegiatan pemasaran. Penelitian ini bertujuan untuk mengetahui pengaruh Viral marketing, media pemasaran online terhadap keputusan pembelian pada Tiktokshop. Populasi dalam penelitian ini yaitu pengguna media sosial Tiktokshop dari generasi milenial dengan jumlah 120. Jumlah sampel ditentukan dengan menggunakan pertimbangan sampel minimum (10 x jumlah item pengukuran). Penelitian ini menggunakan 3 variabel independen (X) dan 1 variabel dependen (Y), menggunakan metode analisis regresi linear. Hasil penelitian dijelaskan bahwa media sosial Tiktokshop dapat meningkatkan aktifitas penjualan dan berpengaruh positif terhadap keputusan pembelian.
PENGARUH MOTIVASI, DISIPLIN KERJA, DAN BEBAN KERJA TERHADAP KINERJA PEGAWAI DI POLRESTA BARELANG BATAM
Authors: Sari Suci Melinda , Evyanto Winda
Published: June 2023

Tujuan penelitiannya ini menelusuri pengaruh motivasi, disiplin kerja, dan beban kerja terhadap kinerja pegawai di Polresta Barelang Batam. Penelitiannya ini dilakukan dengan menerapkan teknik kuantitatif. Sampel penelitian digunakan sebanyak 100 responden yakni pegawai bagian Unit Pelayanan Polresta Barelang Batam tahun 2022  dengan menerapkan teknik sampel jenuh. Dengan memakai teknik analisa data yang meliputi pengujian statistik deskriptif, kualitas data, asumsi klasik, pengaruh, serta hipotesis. Variabel motivasi, disiplin kerja, dan beban kerja memengaruhi kinerja pegawai dengan sebesar 45% dengan sig. 0,00 < 0,05. Di dapatkan motivasi dan disiplin kerja memengaruhi positif signifikan, namun beban kerja memengaruhi negatif signifikan. Akan tetapi secara simultan ketiga variabelnya ini memengaruhi positif dan signifikan terhadap kinerja pegawai di Polresta Barelang Batam.
PENGARUH ULASAN PRODUK, KEMUDAHAN DAN PROMOSI TERHADAP KEPUTUSAN PEMBELIAN PADA SHOPEE DI KOTA BATAM
Authors: Sari Indah Permata , Realize Realize
Published: June 2023

Penelitian ini bertujuan untuk menganalisis  pengaruh ulasan produk,kemudahan dan promosi, terhadap keputusan pembelian.    Penelitian    ini    dilakukan    dengan menggunakan    metode    deskriptif    kuantitatif.    Pengumpulan    data disajikan  dengan  metode  penelitian  kepustakaan  dan  dokumentasi. Teknik  analisis  data  yang  digunakan  adalah  uji  asumsi  klasik,  analisis regresi  linear  berganda,  uji  t,  uji  f  dan  uji  koefisien  determinasi. Analisis dilakukan dengan menggunakan program IBM SPSS Statistic V.26.  Hasil  penelitian  ini  dapat  disimpulkan  sebagai  berikut: (1)Dari hasil  regresi  linear  berganda  bahwa  menyatakan ulasan produk berpengaruh postif dan signifikan secara parsial terhadap keputusan pembelian (2) kemudahan terdapat pengaruh positif signifikan secara parsial terhadap keputusan pembelian (3) bahwasanya promosi terdapat pengaruh positif dan signifikan secara parsial terhadap keputusan pembelian (4) Dari  hasi  Uji  F diketahui    bahwa    secara simultan ulasan prodik,kemudahan dan promosi berpengaruh signifikan terhadap keputusan pembelian pada Shopee.
PENGARUH KEPEMIMPINAN TRANSFORMASIONAL, PEMBERDAYAAN KARYAWAN DAN KEPUASAN KERJA TERHADAP KINERJA KARYAWAN PT. KOTA WOODCRAF FURNITURE JEPARA
Authors: Srilestari Nike Ayu , Indriyaningrum Kis
Published: June 2023

Penelitian ini bertujuan untuk menganalisis pengaruh Kepemimpinan Transformasional, Pemberdayaan Karyawan dan Kepuasan Kerja terhadap Kinerja Karyawan. Jenis data yang digunakan  adalah data primer yaitu data yang diperoleh secara langsung dari sumber asli. Sampel pada penelitian ini sebesar 100 orang. Teknik pengambilan sampel ialah sampling jenuh adalah teknik penentuan sampel bila semua anggota populasi dijadikan sampel. Alat uji pada penelitian ini meliputi uji instrumen terdiri dari validitas dan uji reliabilitas, serta dilakukan uji model, meliputi uji koefisien determinasi (R2) dan uji F. Selanjutnya dilakukan analisis regresi dan uji hipotesis. Hasil penelitian menunjukkan Kepemimpinan Transformasional berpengaruh positif dan signifikan terhadap kinerja karyawan. Pemberdayaan Karyawan berpengaruh positif dan signifikan terhadap kierja karyawan. Kepuasan kerja berpengaruh positif dan signifikan terhadap kinerja karyawan.
PENGARUH DISIPLIN KERJA DAN BEBAN KERJA TERHADAP KINERJA KARYAWAN PADA PT GHIM LI INDONESIA DI KOTA BATAM
Authors: Ginting Jenniwati Br , Siagian Mauli
Published: June 2023

Penelitian ini bertujuan untuk menjawab pertanyaan bagaimana kinerja karyawan di PT dipengaruhi oleh disiplin kerja dan beban kerja. Ghim Li Indonesia di Kota Batam. Untuk strategi pengambilan sampel penelitian ini yaitu random atau acak untuk setiap departemen, partisipannya adalah karyawan PT. 120 orang, Ghim Li Indonesia. Disiplin kerja berpengaruh terhadap kinerja pegawai, berdasarkan hasil pengujian hipotesis, dengan nilai thitung variabel Disiplin Kerja (X1) sebesar 2,070, nilai ttabel sebesar 1,657, dan nilai signifikan sebesar 0,041 lebih kecil dari nilai alpha sebesar 0,05. Nilai thitung variabel beban kerja (X2) sebesar 9,678 dengan nilai ttabel sebesar 1,657 dan nilai signifikansi sebesar 0,000 lebih kecil dari nilai alpha sebesar 0,05, hal ini menunjukkan bahwa beban kerja berpengaruh terhadap kinerja karyawan. Sebaliknya, nilai sig uji F adalah 0,000. < 0,05 dan nilai F hitungnya adalah 54,676 > Dari Tabel 3.07, penulis menarik kesimpulan bahwa Disiplin Kerja dan Beban Kerja berpengaruh signifikan atau signifikan terhadap kinerja pegawai.
Menelisik Makna Riba Pada Bank Muamalat Di Kota Palopo
Authors: Hermila Sahwa , Antong Antong , Usman Halim
Published: June 2023

Penelitian ini bertujuan untuk memajukan perekonomian memiliki strategi  penting agar masyarakat terhindar dari prinsip ribawi dengan pinjaman modal dengan sistem bagi hasil yang tidak mengarah pada sistem bunga. Metode yang di gunakan dalam penelitian adalah Kualitatif dengan menggunakan studi literatur kepustakaan yang menunjukan bahwa riba merupakan tambahan, namun penambahan menimbulkan keadilan,hal ini di jelaskan dalam berbagai sumber termasuk Al-Qur’an. Penelitian ini  dilaksanakan di salah satu Bank Muamalat di kota palopo, hasil penelitian ini yang di temukan berdasarkan hasil wawancara riba adalah suatu nilai tambah yang di kenakan kepada nasabah untuk memenuhi kebutuhan bank, karena bank adalah pengelolah atau  intermediasi dimana intermediasi merupakan suatu fungsi lembaga keuangan bank melalui cara penarikan atau penghimpunan dana dari para nasabah kemudian disalurkan lagi dalam bentuk pinjaman kepada pihak-pihak yang membutuhkan.