bluuebunny/crossref_metadata_2025 huggingface dataset:
Phenological Adaptation of Wheat Varieties to Rising Temperatures: Implications for Yield Components and Grain Quality
Authors: Gulino Davide , Lopes Marta S.
Published: October 2024

This study examined the effects of late sowing, water restrictions, and interannual weather variations on wheat grain yield and quality through field trials in Spain over two growing seasons. Delayed sowing and water scarcity significantly reduced yields, with grain quality mainly affected under rainfed conditions. Early-maturing varieties performed better in these conditions, benefiting from lower temperatures and extended grain-filling periods, leading to higher solar radiation interception, potentially increased photosynthetic activity, and improved yields. These varieties also saved water through reduced total cumulative evapotranspiration from sowing to maturity (ETo TOT), which was advantageous in water-limited environments. In contrast, late-maturing varieties were exposed to higher maximum temperatures during grain filling and experienced greater ETo TOT, leading to lower yields, reduced hectoliter weight, and a lower P/L ratio (tenacity/extensibility). This study highlighted the importance of optimizing temperature exposure and evapotranspiration for improved grain yield and quality, especially under climate change conditions with higher temperatures and water shortages. Notably, it established, for the first time, the importance of phenology on wheat quality of different varieties, suggesting that targeted selection for specific phenology could mitigate the negative impacts of heat stress not only on grain yield but also on grain quality.
Supercritical CO2 and Conventional Extraction of Bioactive Compounds from Different Cultivars of Blackberry (Rubus fruticosus L.) Pomace
Authors: Čechovičienė Indrė , Kazancev Kiril , Hallmann Ewellina , Sendžikienė Eglė , Kruk Marcin , Viškelis Jonas , Tarasevičienė Živilė
Published: October 2024

The main objective of this work was to extract bioactive compounds from different cultivars of blackberry pomace using conventional Soxhlet and supercritical CO2 (SC-CO2) extraction methods. For Soxhlet extraction, two different solvents, ethanol and n-hexane, were used. Qualitative and quantitative composition of fatty acids was determined by GC, carotenoids and chlorophylls by HPLC, and volatile organic compounds were identified with an e-nose based on GC. The yield of the extract was influenced by the extraction, while the qualitative content of the extracts was also dependent on the cultivar. While there were no differences in the types of fatty acids extracted, their content varied significantly depending on the cultivar, extraction method, and their interaction. The results showed that linoleic acid (C18:2), oleic acid (C18:1), and α-linolenic acid (C18:3) were the most prevalent in all cultivars of blackberry pomace extracts. The linoleic acid content varied from 33.33 to 64.77% depending on the variety, and the ratio of omega-6 to omega-3 varied from 3.17% to 5.71%. Significantly higher quantities of carotenoids and chlorophylls were obtained in Soxhlet extraction with n-hexane in all extracts. The major carotenoid in the ‘Orkan’ and ‘Polar’ extracts was lutein, while in the ‘Brzezina’ extract, it was β-carotene. The extraction method has a significant impact on the flavor profile of the extracts.
Insights into Genes Encoding LEA_1 Domain-Containing Proteins in Cyperus esculentus, a Desiccation-Tolerant Tuber Plant
Authors: Zhao Yongguo , Fu Xiaowen , Zou Zhi
Published: October 2024

LEA_1 domain-containing proteins constitute a class of late-embryogenesis-abundant proteins that are highly hydrophilic and predominantly accumulate in mature seeds. Though LEA_1 proteins have been proven to be essential for seed desiccation tolerance and longevity, little information is available on their roles in non-seed storage organs. In this study, a first genome-wide characterization of the LEA_1 gene family was conducted in tigernut (Cyperus esculentus L., Cyperaceae), whose underground tubers are desiccation tolerant with a moisture content of less than 6%. Five family members identified in tigernut are comparative to four to six found in seven other Cyperaceae plants, but relatively more than three reported in Arabidopsis. Further comparison of 125 members from 29 plant species supports early divergence of the LEA_1 family into two phylogenetic groups before angiosperm radiation, and gene expansion in tigernut was contributed by whole-genome duplications occurring after the split with the eudicot clade. These two phylogenetic groups could be further divided into six orthogroups in the momocot clade, five of which are present in tigernut and the remaining one is Poaceae specific. Frequent structural variation and expression divergence of paralogs were also observed. Significantly, in contrast to seed-preferential expression of LEA_1 genes in Arabidopsis, rice, and maize, transcriptional profiling and qRT-PCR analysis revealed that CeLEA1 genes have evolved to predominantly express in tubers, exhibiting a seed desiccation-like accumulation during tuber development. Moreover, CeLEA1 transcripts in tubers were shown to be considerably more than that of their orthologs in purple nutsedge, another Cyperaceae plant producing desiccation-sensitive tubers. These results imply species-specific activation and key roles of CeLEA1 genes in the acquisition of desiccation tolerance of tigernut tubers as observed in orthodox seeds. Our findings not only improve the understanding of lineage-specific evolution of the LEA_1 family, but also provide valuable information for further functional analysis and genetic improvement in tigernut.
Cerium Oxide Nanoparticles (CeO2 NPs) Enhance Salt Tolerance in Spearmint (Mentha spicata L.) by Boosting the Antioxidant System and Increasing Essential Oil Composition
Authors: Haghmadad Milani Maryam , Mohammadi Asghar , Panahirad Sima , Farhadi Habib , Labib Parisa , Kulak Muhittin , Gohari Gholamreza , Fotopoulos Vasileios , Vita Federico
Published: October 2024

Salinity represents a considerable environmental risk, exerting deleterious effects on horticultural crops. Nanotechnology has recently emerged as a promising avenue for enhancing plant tolerance to abiotic stress. Among nanoparticles, cerium oxide nanoparticles (CeO2 NPs) have been demonstrated to mitigate certain stress effects, including salinity. In the present study, the impact of CeO2 NPs (0, 25, and 100 mg L−1) on various morphological traits, photosynthetic pigments, biochemical parameters, and the essential oil profile of spearmint plants under moderate (50 mM NaCl) and severe (100 mM NaCl) salinity stress conditions was examined. As expected, salinity reduced morphological parameters, including plant height, number of leaves, fresh and dry weight of leaves and shoots, as well as photosynthetic pigments, in comparison to control. Conversely, it led to an increase in the content of proline, total phenols, malondialdehyde (MDA), hydrogen peroxide (H2O2), and antioxidant enzyme activities. In terms of CeO2 NP applications, they improved the salinity tolerance of spearmint plants by increasing chlorophyll and carotenoid content, enhancing antioxidant enzyme activities, and lowering MDA and H2O2 levels. However, CeO2 NPs at 100 mg L−1 had adverse effects on certain physiological parameters, highlighting the need for careful consideration of the applied concentration of CeO2 NPs. Considering the response of essential oil compounds, combination of salinity stress and CeO2 treatments led to an increase in the concentrations of L-menthone, pulegone, and 1,8-cineole, which are the predominant compounds in spearmint essential oil. In summary, foliar application of CeO2 NPs strengthened the resilience of spearmint plants against salinity stress, offering new insights into the potential use of CeO2 NP treatments to enhance crop stress tolerance.
Influence of Absorbent Composition and Operating Parameters on CO2 Removal Efficiency Using Aqueous Blends of 1-Dimethylamino-2-propanol in Tray Column
Authors: Fu Dong , Chen Jianjun , Wang Xueli , Wang Lemeng
Published: October 2024

The CO2 absorption performance in aqueous blends of monoethanolamine (MEA)—1-dimethylamino-2-propanol (DMA2P) and piperazine (PZ)—DMA2P was investigated using a bench-scale tray column under atmospheric pressure. The removal efficiency of CO2 (ηCO2) and the overall volumetric mass transfer coefficient (KGav) in DMA2P-MEA and DMA2P-PZ solutions were determined at 313.2 K. The simulated flue gas was composed of 15% (mole fraction) CO2 and 85% N2. The effects of inlet gas flow rate (G), absorbent composition (w), inlet liquid flow rate (L), and plate number (NP) on ηCO2 and KGav were demonstrated. Our results showed that the absorption of CO2 in DMA2P aqueous solution can be accelerated by the addition of MEA/PZ in a tray column, and both ηCO2 and KGav can be significantly improved.
Cost-Effective Optimization of the Transfructosylation Activity of an Invertase Produced from Aspergillus carbonarius PC-4 Using Pineapple Crown and Determination of Its Biochemical Properties
Authors: Batista Ryhára Dias , Carvalho do Nascimento Gustavo , Carvalho Nayara Bezerra , Leite Paula Candido , Basso Rodrigo Correa , Morales Sergio Andres Villalba , Xavier Michelle da Cunha Abreu , Perna Rafael Firmani , Almeida Alex Fernando de
Published: October 2024

Fructooligosaccharides are prebiotic sugars that are widely used in the production of functional foods, which can be produced enzymatically by the transfructosylation reaction of sucrose. This work aimed to optimize the production of an invertase with high transfructosylation activity from Aspergillus carbonarius PC-4 using pineapple crown as the inducer substrate and evaluate its biochemical properties. The culture medium was optimized using a Plackett–Burman experimental design and a central composite rotatable design, resulting in a maximum transfructosylation activity of 65.33 U/mL at 72 h of cultivation. The cultivation parameters were Yp/s = 1070.75 U/g and PP = 2771.48 U/h, which showed an increase of 5.2-fold in the enzyme produced. The optimum temperature (50 °C) and pH (5.0) for the enzymatic activity were obtained by a CCR design. The enzyme showed a half-life of 60 min at 40 °C. In conclusion, the invertase produced from A. carbonarius PC-4 using agro-industrial waste (pineapple crown) and an inorganic nitrogen source (ammonium nitrate) exhibits high transfructosylation activity that can be used as a potential source for the production of fructooligosaccharides.
State of Health Estimation of Lithium-Ion Battery Using Multi-Health Features Based on Savitzky–Golay Filter and Fitness-Distance Balance- and Lévy Roulette-Enhanced Coyote Optimization Algorithm-Optimized Long Short-Term Memory
Authors: Li Hongbiao , Gao Dengke , Shi Linlong , Zheng Fei , Yang Bo
Published: October 2024

Accurate and reliable state of health (SOH) estimation is extremely crucial for the safe and stable operation of lithium-ion batteries (LIBs). In this paper, a method based on Lévy roulette- and fitness-distance balance-enhanced coyote optimization algorithm-optimized long short-term memory (LRFDBCOA-LSTM) is employed for SOH estimation of LIB. Firstly, six health features are extracted from battery charging and discharging data, and Savitzky–Golay is used to filter the feature data to improve correlation between feature and SOH. Then, Lévy roulette and fitness-distance balance (FDB) strategies are used to improve the coyote optimization algorithm (COA), i.e., LRFDBCOA. Meanwhile, the improved algorithm is used to optimize the internal parameters of long short-term memory (LSTM) neural network. Finally, the effectiveness of the proposed model is comprehensively validated using five evaluation indicators based on battery data obtained under three different testing conditions. The experimental results manifest that after algorithm improvement and network parameter optimization, the performance of the model is significantly improved. In addition, the method has high estimation accuracy, strong generalization, and strong robustness for SOH estimation with a maximum R2 of 0.9896 and minimum R2 of no less than 0.9711.
Optimization and Efficiency of Novel Magnetic-Resin-Based Approaches for Enhanced Nickel Removal from Water
Authors: Maletin Marija , Nikić Jasmina , Gvoić Vesna , Pešić Jovana , Cvejić Željka , Tubić Aleksandra , Agbaba Jasmina
Published: October 2024

Nickel contamination in water is a critical issue due to its toxicity and persistence. This study presents a novel magnetic resin, developed by modifying Lewatit® MonoPlus TP 207 with magnetite nanoparticles, to enhance adsorption capacity and facilitate efficient separation. A Definitive Screening Design (DSD) was employed to identify and optimize key parameters affecting nickel adsorption, including pH, resin dosage, initial nickel concentration, and the presence of competing ions (calcium and magnesium). The DSD analysis revealed that pH and magnesium concentration were the most significant factors influencing nickel removal. Optimal conditions were determined as pH 7, 270 min contact time, resin dosage of 0.5 mL/L, initial nickel concentration of 110 µg/L, calcium concentration of 275 mg/L, and magnesium concentration of 52.5 mg/L, achieving a maximum removal efficiency of 99.21%. The magnetic resin exhibited enhanced adsorption capacity and faster kinetics compared to the unmodified resin, leading to more efficient nickel removal. Moreover, its magnetic properties facilitated rapid separation from treated water, offering practical advantages for real-world applications. This study demonstrates the effective use of DSD in optimizing adsorption parameters and underscores the potential of magnetic resin as a sustainable and efficient adsorbent for water treatment.
The Role of Fermentation and Drying on the Changes in Bioactive Properties, Seconder Metabolites, Fatty Acids and Sensory Properties of Green Jalapeño Peppers
Authors: Mohamed Ahmed Isam A. , AlJuhaimi Fahad , Özcan Mehmet Musa , Uslu Nurhan , Walayat Noman
Published: October 2024

In this study, the influence of fermentation and different drying techniques on the bioactive components, antioxidant activity, phenolic components, fatty acids, nutrients and sensory characteristics of fresh and processed jalapeño peppers was investigated. At the end of the fermentation, the pH, acidity and salt values of the brine were determined as 3.38, 0.09% and 6.02 g/100 mL, respectively. The oil results of pepper samples were found between 2.0% (microwave and air) and 2.60% (oven). Total carotenoid and total phenolic amounts of fresh (control) and processed peppers (air, conventional, microwave and fermentation) were characterized to be between 3.38 (fermented) and 65.68 µg/g (air) to 45.81 (fermented) and 350.69 mg GAE/100 g (microwave), respectively. Total flavonoid quantities of fresh and processed pepper samples were defined to be between 14.17 (fresh) and 482.74 mg/100 g (microwave). 3,4-dihydroxybenzoic acid and catechin amounts in fresh and processed jalapeño peppers were defined to be between 0.43 (fermented) and 11.0 mg/100 g (microwave) to 1.36 (fermented) and 44.87 mg/100 g (microwave), respectively. The predominant fatty acids of pepper oils were palmitic, oleic and linoleic acid. The oleic acid amounts of fresh and processed jalapeño pepper oils were specified to be between 9.52% (air drying) and 29.77% (fermented), while the linoleic acid values of pepper oils vary between 10.84% (fermented) and 68.38% (air drying). The major elements of fresh and processed peppers were K, P, S, Ca, Mg, Fe and Zn in decreasing order. Protein amounts in fresh and processed jalapeño peppers were characterized to be between 8.59 (fermented) and 12.22% (oven). As a result of panelist evaluations, the most appreciated features (4.83 score) were the flavor, color and texture feature.
The Meaning of the Patriarch’s Coming from the West: A Study of Triptych of Three Zen Masters: Linji, Bodhidharma, and Deshan
Authors: Zhang Yuyu
Published: October 2024

In the mid-seventeenth century, Chinese Chan master Yinyuan Longqi 隱元隆琦 (Jp. Ingen Ryūki, 1592–1673), accompanied by several disciples, traveled to Japan and established Ōbaku Zen, a new sect of Zen Buddhism in Tokugawa Japan. Ōbaku art, particularly portrait paintings of Ōbaku abbots and their spiritual predecessors, became critical representations of the sect and greatly influenced later Japanese Buddhist art. While much of the existing scholarship focuses on the artistic and stylistic aspects of Ōbaku portraiture, this paper emphasizes its religious context and doctrinal dimensions. Building on Elizabeth Horton Sharf’s inquiry into the “meaning and function” of Ōbaku portrait painting, the paper investigates how Ōbaku doctrine is expressed through these images. Using the Triptych of Three Zen Masters: Linji, Bodhidharma, and Deshan as a case study, this paper explores the role of portraiture in visually conveying Ōbaku teachings and the religious aspirations of those Chinese immigrant monks. By examining the integration of image, inscription, and seal as a unified “pictorial trinity”, the paper argues that Ōbaku portraiture embodies the sect’s distinct doctrine, rooted in Ming-era Chan practices such as beating, shouting, and strict dharma transmission. Moreover, the prominence of Bodhidharma in Ōbaku portraits, as illustrated in the triptych, reflects these Chinese immigrant monks’ desire to emulate Bodhidharma in spreading the dharma and expanding their sect’s influence in a new land.
Analysis of Farmers’ Perceptions on Sealing Techniques for Runoff Harvesting Ponds: A Case Study from Burkina Faso
Authors: Kaboré Tégawindé Vanessa Rosette , Keïta Amadou , Lawane Gana Abdou , Niang Dial , Boubé Bassirou
Published: October 2024

Water conservation in arid and semi-arid regions faces significant challenges due to low and irregular rainfall, worsened by climate change, which negatively affects rain-fed crop productivity. Various techniques, including supplemental irrigation using runoff harvesting ponds, aim to address these issues but often suffer from water loss due to infiltration, influenced by the pond liner type. This study uses a factorial analysis to assess the farmers’ perceptions of four pond sealing techniques. Using the Waso-2 method, a survey conducted in 2022 among 41 rainwater harvesting pond owners across three regions of Burkina Faso revealed that farmers prioritized impermeability and ease of maintenance over cost and availability. Concrete, scoring 16/20, was the most preferred, chosen by over 75% of farmers for its durability and resistance to weathering, despite its high cost. Geomembrane, with a score of 12/20, was valued for its waterproofing properties but had durability concerns. Clay, although cheap and available, scored 8/20 due to poor waterproofing on unstable ground. Bitumen, the least favored with a score of 6/20, was hindered by scarcity and lack of familiarity. To enhance supplemental irrigation in Burkina Faso and similar regions, waterproof concrete or durable geomembrane liners are recommended. Further research into improving bitumen and clay liners is also suggested. These findings provide key insights into farmers’ preferences, offering guidance for developing effective water conservation strategies to boost agricultural productivity and address food security challenges in the context of climate change.
Aberrant Number of Vessels in the Umbilical Cord: What Do We Know?
Authors: Remorgida Valentino , Nicosia Anthony , Leo Livio , Troìa Libera , Libretti Alessandro
Published: October 2024

The umbilical cord, comprising three vital blood vessels, serves as the lifeline between mother and fetus. Prenatal care emphasizes detailed ultrasound examinations of the umbilical cord and postnatal inspections of the placenta and cord to preemptively address potential complications. Studies have consistently shown a significant link between a single umbilical artery and unfavorable perinatal consequences, such as mortality and congenital abnormalities. Conversely, the impact of additional vessels remains uncertain. This review is dedicated to enhancing our understanding and refining diagnostic and therapeutic approaches in prenatal healthcare. The objective is to identify knowledge gaps and propose evidence-based solutions to improve care for pregnant women and their unborn babies. The presence of a single umbilical artery in prenatal diagnosis may signify potential risks for fetal anomalies and adverse pregnancy outcomes such as hemodynamic instability, ischemia, and an increased likelihood of intrauterine growth restriction. Additionally, even the presence of supernumerary vessels may be associated with fetal malformations. Serial fetal evaluations are recommended for detecting anomalies and monitoring fetal growth throughout pregnancy. Despite the generally benign nature of isolated SUA and supernumerary vessels, close monitoring and comprehensive prenatal care are essential to ensuring optimal outcomes for both mother and baby.
Retention Mechanisms of Basic Compounds in Liquid Chromatography with Sodium Dodecyl Sulfate and 1-Hexyl-3-Methylimidazolium Chloride as Mobile Phase Reagents in Two C18 Columns
Authors: Tereba-Mamani Carlos Josué , Garcia-Alvarez-Coque Maria Celia , Ruiz-Ángel María José
Published: October 2024

Reversed-phase liquid chromatography (RPLC) relies on a non-polar stationary phase and a more polar hydro-organic mobile phase, where compound retention is primarily governed by hydrophobicity, with more hydrophobic compounds being retained longer. The introduction of secondary equilibria in the chromatographic system through additives, such as anionic surfactants and ionic liquids (ILs), was proposed to mitigate ionic interactions between positively charged analytes and the anionic free silanol groups in non-endcapped stationary phases, thereby preventing increased retention and peak tailing. Additionally, the combined hydrophobic and ionic interactions between cationic analytes and the ions in these additives was demonstrated to create mixed retention mechanisms that influence retention and selectivity. In this regard, this study investigates aqueous chromatographic systems incorporating both the anionic surfactant sodium dodecyl sulfate (SDS) and the IL 1-hexyl-3-methylimidazolium chloride as mobile phase reagents. This combination of reagents modulates the retention, eliminating the need for organic solvents and resulting in highly sustainable HPLC procedures. The chromatographic behavior was assessed using two different C18 columns (Zorbax Eclipse and XTerra-MS). The strength of solute interactions was estimated by calculating equilibrium parameters and the contributions of hydrophobic and ionic interactions through simple mathematical models. Focusing on the retention of six basic drugs (β-adrenoceptor antagonists), the study highlighted the significant role of ionic interactions. The results demonstrate the feasibility of using aqueous systems combining SDS and an IL for the efficient separation of moderately polar basic compounds without the use of organic solvents.
Cultural Conflict and Disappointment: Hongkongers’ Sentiments Toward Taiwanese Authorities Amid Cross-Strait Tensions
Authors: Ho Wing-Chung , Fung Ken Ka-wo
Published: October 2024

The failure of the democratic movement during 2014–2020 prompted tens of thousands of Hongkongers (~40,000) to reluctantly leave their hometown and migrate to Taiwan to seek a freer future. Taiwan’s cultural similarity to Hong Kong, together with Taiwan’s democracy and geographic proximity, are commonly recognized as pull factors of migration. However, the intensifying cross-strait tensions since late 2021 have witnessed Taipei tighten its approval of Hongkongers’ applications for permanent residency mainly in fear of the infiltration of Chinese agents. Based on mixed-methods in-depth interviews (N = 15) and an online survey (N = 147) with Hong Kong migrants, this paper reveals their complex experience in adapting to the Taiwan way of life, becoming frustrated by Taipei’s attitudinal change, and contemplating onward migration. The findings reveal underlying cultural differences between Hong Kong and Taiwanese societies—manifesting as a cultural conflict—amid fears of an encroaching communist China.
Factors Impacting Perceptions of Gender Inequality in the Spanish Society
Authors: Méndez-Suárez Mariano , Monfort Abel
Published: October 2024

This study uses Ordinary Least Squares Multiple Regression with data on perceptions regarding gender equality from the Spanish general population. Overall, the results indicate that perceptions of equal treatment under the law and equality in political life are significantly associated with perceptions of gender equality. However, perceptions of discrimination in education do not seem to affect perceptions of gender equality significantly. In addition, the results show a clear association between the belief that gender equality leads to a fairer society and the perception of gender equality itself. Results also suggest that while certain perceptions related to the law, society, and political life are instrumental in shaping views on gender inequality, there remains a foundational level of perceived inequality in Spanish society. As a concluding remark, when examining the impact of female representation in leadership positions, the results provide empirical support that the presence of women in leadership positions improves the perception of gender equity in the contexts in which it occurs; this fact reflects the importance of promoting the participation of women in management positions through public policies.
Gender-Based Homophily in International Research Collaborations
Authors: Löther Andrea , Freund Frederike
Published: October 2024

Women researchers in postdoc career stages still do not participate to the same extent in international academic mobility as men do. As a novel approach to better understand gender inequalities in international academic mobility, we investigate the structure of research collaborations and bring into focus the host researchers. Our central theoretical tool is the distinction between compositional and behavioral homophily. Using quantitative data from two German Humboldt Foundation programs sponsoring collaborations between international researchers and academic hosts in Germany, we ask (a) to what extent are gender-homophilous research collaborations caused by compositional or behavioral homophily; (b) what factors influence gender-based homophily; and (c) whether men or women tend more towards gender-homophilous collaborations. We detected behavioral homophily in research collaborations mainly when taking the potential pool of eligible women researchers as the reference group. The results on influencing factors are ambiguous and need further investigation. Furthermore, our results show that men tended more towards gender-homophilous collaborations than women. Our results suggest that gender inequalities in international academic mobility are linked to behavioral homophily and that exploring the role of host researchers is crucial to understanding—and overcoming—the under-representation of women in international academic mobility.
Exploring the Extremes: The Impact of Radical Right-Wing Populism on Conspiracy Beliefs in Austria
Authors: Hofmann Diana Lucia
Published: October 2024

(1) Background: Populist radical right-wing parties and politicians have used conspiracy theories to perpetuate the antagonism between an evil elite conspiring against the good and unknowing people. Yet, less is known about whether and to what extent radical right-wing populism at the individual level is associated with different conspiracy beliefs. This analysis explores how the main components of radical right-wing populism—populist, nativist, and authoritarian attitudes—relate to both a general conspiracy mentality and specific conspiracy theories prevalent in political discourse. (2) Methods: Using data from an original 2023 online survey conducted in Austria, a stronghold of the populist radical right, this study includes new questions on immigration, COVID-19, and climate change, as well as a conspiracy mentality scale. (3) Results: The analyses reveal that all the main components are positively associated with different conspiracy beliefs, albeit to varying degrees. Across models, the strongest predictor is populism, followed by nativism and authoritarianism. Nativism varies the most across different conspiracy beliefs and is particularly associated with the belief in conspiracy theories related to immigration and climate change. (4) Conclusions: The results highlight the prevalence of radical right-wing populist attitudes across various conspiracy beliefs, reflecting how populist radical right-wing actors leverage conspiracy theories in their political discourse.
A Comparative Study of Bazaar Cultural Spaces in Central Asia and China
Authors: Ding Yingjie , Fan Tao , Wang Huan , Yang Zhao
Published: October 2024

With the advancement of modernization, traditional bazaars have encountered challenges, such as diminished vitality. Concurrently, the trend of integrating cultural spaces into bazaars has become increasingly evident. Understanding the relationship between bazaars and cultural spaces, as well as the preferences of users of these spaces, is crucial for enhancing bazaar vitality. Employing field research, questionnaire surveys, cross-analysis, and the narrative preference method, this paper compares the bazaar cultural spaces of Central Asia and Chinese from four perspectives: the current state of the bazaar, development overview, user preferences, and cultural space type preferences. This aims to deepen the understanding of the commonalities and differences between the two regions, and to explore the development trends of bazaars and their cultural spaces. The study reveals that (1) Spaces with diversified functions, high accessibility, and openness can enhance the vitality of the bazaar; (2) There exists a synergistic, mutually beneficial relationship between the bazaar and the cultural spaces; (3) Central Asian residents place greater emphasis on the environmental quality of the bazaar and the engaging content of its cultural spaces. In contrast, Chinese residents are more focused on the accessibility of the bazaar and the openness of the cultural spaces; (4) The function of art and culture is the preferred type of cultural space in the bazaar among residents of both regions. This study significantly contributes to the planning, design, and optimization of bazaars and their cultural spaces.
Bleaching Agents: A Review of Their Utilization and Management
Authors: Kulkarni Deepali , Jaspal Dipika , Itankar Nilisha , Petrounias Petros , Rogkala Aikaterini , Lampropoulou Paraskevi
Published: October 2024

Exposure to disinfectants, cleansers, and bleaching chemicals irritates the eyes, respiratory systems, and skin, triggering asthma and allergic rhinitis symptoms. Bleach, as the major constituent of cleansers, when used improperly or mixed with other indoor cleaning agents, produces harmful halogenated volatile organic compounds. This manuscript assesses the influence of excessive exposure to disinfectants, including bleaching agents, when used against infectious conditions related to SARS-COVID-19 and its management. The use and impact of different bleaching agents in cleansing and their associated problems have been analyzed and presented in this review. This analysis focuses on the conventional and post-pandemic approach towards bleaches. Usage of bleaching agents increased by a staggering 20.4% and 16.4% from January to March 2020 compared to the same period in 2018 and 2019. Mounting use of bleaching agents during the COVID-19 pandemic resulted in negative health effects like asthma, eye irritation, and skin allergies. An approximately 42% rise in poisoning cases, including a few deaths, has been associated with exposure to harmful chemicals involving bleaches during the recent pandemic. Bleaching agents are the primary sources of hazardous indoor pollutants; therefore, despite their importance in disinfection, their utility must be substantiated based on legal guidelines, disposal, and remedial measures. Thus, conducting future occupational exposure assessment studies for bleach hazard management is crucial.
Resilient Coastal Protection Infrastructures: Probabilistic Sensitivity Analysis of Wave Overtopping Using Gaussian Process Surrogate Models
Authors: Kent Paul , Abolfathi Soroush , Al Ali Hannah , Sedighi Tabassom , Chatrabgoun Omid , Daneshkhah Alireza
Published: October 2024

This paper presents a novel mathematical framework for assessing and predicting the resilience of critical coastal infrastructures against wave overtopping hazards and extreme climatic events. A probabilistic sensitivity analysis model is developed to evaluate the relative influence of hydrodynamic, geomorphological, and structural factors contributing to wave overtopping dynamics. Additionally, a stochastic Gaussian process (GP) model is introduced to predict the mean overtopping discharge from coastal defences. Both the sensitivity analysis and the predictive models are validated using a large homogeneous dataset comprising 163 laboratory and field-scale tests. Statistical evaluations demonstrate the superior performance of the GPs in identifying key parameters driving wave overtopping and predicting mean discharge rates, outperforming existing regression-based formulae. The proposed model offers a robust predictive tool for assessing the performance of critical coastal protection infrastructures under various climate scenarios.
Optimizing Planting Density, Irrigation, and Nitrogen Application Can Improve Rapeseed Yield in Xinjiang’s Aksu by Reducing the Lodging Rate
Authors: Guo Wenbo , Li Haifeng , Simayi Silayiding , Wen Yunmeng , Bian Qingyong , Zhu Jinquan , Liu Zhigang , Su Hanming , Wei Yanhong , Liu Guohong , Fu Yanbo
Published: October 2024

This study aimed to investigate the effects of planting density, irrigation volume, and nitrogen application on the resistance of rapeseed to lodging and yield and to provide technical support for achieving high yield and lodging resistance. We employed an L9 (34) orthogonal array, different planting densities, irrigation levels, and nitrogen applications to investigate their impact on rapeseed lodging and yield. The results showed the following: (1) Irrigation had the greatest effect on rapeseed lodging. This effect was most pronounced for the combination (A3B3C2), which exhibited the most severe lodging phenomenon (90%). Planting density had the greatest effect on yield, and the optimal combination was A2B2C3, which reached 3744 kg/hm2 in 2023 and 3420 kg/hm2 in 2024. (2) The agronomic practices increased the content of lignin, cellulose, hemicellulose, crude fiber, pectin, and soluble sugar fractions in the stalks by enhancing their flexural, puncture, and stress resistance. This led to the highest yield while reducing the rate of lodging. This emphasizes the importance of agricultural practices for rapeseed lodging and yield, providing critical insights into rapeseed cultivation in the Aksu region of Xinjiang.
Cyber Resilience Limitations in Space Systems Design Process: Insights from Space Designers
Authors: Shahzad Syed , Joiner Keith , Qiao Li , Deane Felicity , Plested Jo
Published: October 2024

Space technology is integral to modern critical systems, including navigation, communication, weather, financial services, and defence. Despite its significance, space infrastructure faces unique cyber resilience challenges exacerbated by the size, isolation, cost, persistence of legacy systems, and lack of comprehensive cyber resilience engineering standards. This paper examines the engineering challenges associated with incorporating cyber resilience into space design, drawing on insights and experiences from industry experts. Through qualitative interviews with engineers, cybersecurity specialists, project managers, and testers, we identified key themes in engineering methodologies, cybersecurity awareness, and the challenges of integrating cyber resilience into space projects. Participants emphasised the importance of incorporating cybersecurity considerations from the earliest stages of design, advocating for principles such as zero-trust architecture and security by design. Our findings reveal that experts favour Model-Based Systems Engineering (MBSE) and Agile methodologies, highlighting their synergy in developing flexible and resilient systems. The study also underscores the tension between principles-based standards, which offer flexibility but can lead to inconsistent implementation, and compliance-based approaches, which provide clear measures but may struggle to adapt to evolving threats. Additionally, the research recognises significant barriers to achieving cyber resilience, including insider threats, the complexity of testing and validation, and budget constraints. Effective stakeholder engagement and innovative funding models are crucial for fostering a culture of cybersecurity awareness and investment in necessary technologies. This study highlights the need for a comprehensive cyber resilience framework that integrates diverse engineering methodologies and proactive security measures, ensuring the resilience of space infrastructure against emerging cyber threats.
Spatiotemporal Analysis of Complex Emission Dynamics in Port Areas Using High-Density Air Sensor Network
Authors: Pan Jun , Wang Ying , Qin Xiaoliang , Gali Nirmal Kumar , Fu Qingyan , Ning Zhi
Published: October 2024

Cargo terminals, as pivotal hubs of mechanical activities, maritime shipping, and land transportation, are significant sources of air pollutants, exhibiting considerable spatiotemporal heterogeneity due to the complex and irregular nature of emissions. This study employed a high-density air sensor network with 17 sites across four functional zones in two Shanghai cargo terminals to monitor NO and NO2 concentrations with high spatiotemporal resolution post sensor data validation against regulatory monitoring stations. Notably, NO and NO2 concentrations within the terminal surged during the night, peaking at 06:00 h, likely due to local regulations on heavy-duty diesel trucks. Spatial analysis revealed the highest NO concentrations in the core operational areas and adjacent roads, with significantly lower levels in the outer ring, indicating strong emission sources and limited dispersion. Employing the lowest percentile method for baseline extraction from high-resolution data, this study identified local emissions as the primary source of NO, constituting over 80% of total emissions. Elevated background concentrations of NO2 suggested a gradual oxidation of NO into NO2, with local emissions contributing to 32–70% of the total NO2 concentration. These findings provide valuable insights into the NO and NO2 emission characteristics across different terminal areas, aiding decision-makers in developing targeted emission control policies.
Characterization of Kunitz-Domain Anticoagulation Peptides Derived from Acinetobacter baumannii Exotoxin Protein F6W77
Authors: Sun Fang , Deng Xiaolin , Gao Huanhuan , Ding Li , Zhu Wen , Luo Hongyi , Ye Xiangdong , Luo Xudong , Chen Zongyun , Qin Chenhu
Published: October 2024

Recent studies have revealed that the coagulation system plays a role in mammalian innate defense by entrapping bacteria in clots and generating antibacterial peptides. So, it is very important for the survival of bacteria to defend against the host coagulation system, which suggests that bacterial exotoxins might be a new source of anticoagulants. In this study, we analyzed the genomic sequences of Acinetobacter baumannii and a new bacterial exotoxin protein, F6W77, with five Kunitz-domains, KABP1-5, was identified. Each Kunitz-type domain features a classical six-cysteine framework reticulated by three conserved disulfide bridges, which was obviously similar to animal Kunitz-domain peptides but different from plant Kunitz-domain peptides. Anticoagulation function evaluation showed that towards the intrinsic coagulation pathway, KABP1 and KABP5 had apparently inhibitory activity, KABP4 had weak inhibitory activity, and KBAP2 and KABP3 had no effect even at a high concentration of 20 μg/mL. All five Kunitz-domain peptides, KABP1-5, had no inhibitory activity towards the extrinsic coagulation pathway. Enzyme-inhibitor experiments showed that the high-activity anticoagulant peptide KABP1 had apparently inhibitory activity towards two key coagulation factors, Xa and XIa, which was further confirmed by pull-down experiments that showed that KABP1 can bind to coagulation factors Xa and XIa directly. Structure-function relationship analyses of five Kunitz-type domain peptides showed that the arginine of the P1 site of three new bacterial anticoagulants, KABP1, KABP4 and KABP5, might be the key residue for their anticoagulation activity. In conclusion, with bioinformatics analyses, peptide recombination, and functional evaluation, we firstly found bacterial-exotoxin-derived Kunitz-type serine protease inhibitors with selectively inhibiting activity towards intrinsic coagulation pathways, and highlighted a new interaction between pathogenic bacteria and the human coagulation system.
Ecuador Towards Zero Leprosy: A Twenty-Three-Year Retrospective Epidemiologic and Spatiotemporal Analysis of Leprosy in Ecuador
Authors: Hernandez-Bojorge Santiago , Gardellini Tatiana , Parikh Jeegan , Rupani Neil , Jacob Benjamin , Hoare Ismael , Calvopiña Manuel , Izurieta Ricardo
Published: October 2024

Ecuador has gone through a significant reduction in new cases from 2000 (106) to 2023 (12), suggesting a trend towards zero leprosy. An ecological spatiotemporal study design was used to describe the epidemiological distribution of the disease in the country during 2000–2023. Leprosy cases registered by the surveillance system of the Ecuadorian Ministry of Public Health were the data utilized for the study. From January 2000 to December 2023, 1539, incidence cases were diagnosed with leprosy in Ecuador. At the time of diagnosis, the median age was 54 years. Most of the cases were males (71.5%). The proportion of incidence cases in subjects over 50 years was 63% and 1.5% in children ≤ 15 years old. The yearly incidence rate ranged from 8.5/1,000,000 population in 2000 to 0.68/1,000,000 population in 2023, remaining within the low-endemic parameter. In total, 35 cantons reported newly detected leprosy cases in the year 2000. By the end of 2023, only eight cantons actively reported cases of leprosy. High-risk clusters for leprosy were detected in the tropical coastal region of Ecuador. The provinces with the highest number of cases during the study period were Guayas (44.8%) and Los Rios (15.7%), with zero cases being found in the Galapagos Islands. Our study is unique in that it documents a retrospective dataset over a two-decade timespan from a South American country that has effectively applied global guidelines for the control and elimination of leprosy.
Chronic Rheumatologic Disease in Chikungunya Virus Fever: Results from a Cohort Study Conducted in Piedecuesta, Colombia
Authors: Lozano-Parra Anyela , Herrera Víctor , Calderón Carlos , Badillo Reynaldo , Gélvez Ramírez Rosa Margarita , Estupiñán Cárdenas María Isabel , Lozano Jiménez José Fernando , Villar Luis Ángel , Rojas Garrido Elsa Marina
Published: October 2024

This study aimed to determine the incidence of post-chikungunya chronic rheumatism (pCHIK-CR) and its impact on quality of life (QoL) and chronic fatigue in adults seven years after the 2014–2015 CHIKV outbreak in Piedecuesta, Colombia. We evaluated 78 adults (median age: 30 years, IQR: 21.0; women 60.3%) with confirmed CHIKV infection. In 2022, participants underwent a GALS examination and completed surveys on disability, stiffness, health status, and fatigue. A rheumatologist evaluated patients who reported arthralgia, morning stiffness, and abnormal GALS examination. Chronic fatigue was defined as fatigue persisting for over six months. Seven years after infection, 14.1% of participants were classified as pCHIK-CR cases, 41.0% as having non-inflammatory pain, likely degenerative (NIP-LD), and 44.9% without rheumatic disease (Wo-RM). Patients with pCHIK-CR and NIP-LD exhibited significantly worse QoL compared to Wo-RM cases. Chronic fatigue prevalence increased from 8.6% in Wo-RM patients to 25.0% in NIP-LD and 54.6% in pCHIK-CR cases. This study implemented a comprehensive clinical assessment to objectively estimate and characterize the incidence of chronic rheumatological disease attributed to CHIKV infection. One in seven cases with CHIKV infection develops pCHIK-CR, which impacts both QoL and chronic fatigue. This study contributes to understanding the burden of these arboviruses in the medium term.
The Effect of Larval Exposure to Heavy Metals on the Gut Microbiota Composition of Adult Anopheles arabiensis (Diptera: Culicidae)
Authors: Singh Ashmika , Misser Shristi , Allam Mushal , Chan Wai-Yin , Ismail Arshad , Munhenga Givemore , Oliver Shüné V.
Published: October 2024

Anopheles arabiensis is a highly adaptable member of the An. gambiae complex. Its flexible resting behaviour and diverse feeding habits make conventional vector control methods less effective in controlling this species. Another emerging challenge is its adaptation to breeding in polluted water, which impacts various life history traits relevant to epidemiology. The gut microbiota of mosquitoes play a crucial role in their life history, and the larval environment significantly influences the composition of this bacterial community. Consequently, adaptation to polluted breeding sites may alter the gut microbiota of adult mosquitoes. This study aimed to examine how larval exposure to metal pollution affects the gut microbial dynamics of An. arabiensis adults. Larvae of An. arabiensis were exposed to either cadmium chloride or copper nitrate, with larvae reared in untreated water serving as a control. Two laboratory strains (SENN: insecticide unselected, SENN-DDT: insecticide selected) and F1 larvae sourced from KwaZulu-Natal, South Africa, were exposed. The gut microbiota of the adults were sequenced using the Illumina Next Generation Sequencing platform and compared. Larval metal exposure affected alpha diversity, with a more marked difference in beta diversity. There was evidence of core microbiota shared between the untreated and metal-treated groups. Bacterial genera associated with metal tolerance were more prevalent in the metal-treated groups. Although larval metal exposure led to an increase in pesticide-degrading bacterial genera in the laboratory strains, this effect was not observed in the F1 population. In the F1 population, Plasmodium-protective bacterial genera were more abundant in the untreated group compared to the metal-treated group. This study therefore highlights the importance of considering the larval environment when searching for local bacterial symbionts for paratransgenesis interventions.