bluuebunny/crossref_metadata_2025 huggingface dataset:
Cost-Effective Staining Alternatives to Immunohistochemistry for Keratin Demonstration in Oral Epithelial Pathologies
Authors: Ghritlahare Himanta , Einstein A. , Patel Swatantra , Kerketta Rashmi C. , Mishra Shubhangi D. , Kujur Shirish K.
Published: August 2024

ABSTRACT

Background:

Demonstrating keratin is crucial in diagnosing various epithelial pathologies and is typically done through histological and immunohistochemical (IHC) methods. While IHC staining for keratin is highly specific, it can be costly and time-consuming. Therefore, common histological staining methods for keratin, suitable for routine histotechniques labs, are gaining importance.

Methodology:

Twenty formalin-fixed, paraffin-embedded tissue blocks, each representing histologically confirmed normal oral mucosa (NOM), hyperorthokeratosis (HOK), and well-differentiated squamous cell carcinoma (WDSCC), were retrieved. Five histological sections of 4-μ thickness from each block were stained using routine hematoxylin and eosin (H and E), modified pap stain (mPap), Ayoub-Shklar (AS), Dane-Herman (DH), and Alcian blue-PAS stains (AB-PAS). Two independent observers evaluated the stained sections and scored staining specificity and intensity. Statistical comparisons were made.

Results:

All sections of NOM, HOK, and WDSCC showed positive staining for keratin with each of the five stains used. The staining specificity and intensity scores were highest with the AS stain and lowest with the AB-PAS stain.

Conclusion:

Routine H and E, mPap, AS, and DH stains effectively stained keratin with adequate intensity in NOM, HOK, and WDSCC. However, while AB-PAS stain also positively stained keratin, its staining intensity was poor across all three tissue types.
Ocular Manifestations of Systemic Diseases: Implications for Comprehensive Patient Care
Authors: Kumar Sunil , Deepankar  , Kiran Neha , Mahato Rohit Kumar
Published: August 2024

ABSTRACT

Background:

Ocular manifestations of systemic diseases pose significant challenges to clinicians due to their diverse presentations and potential impact on vision. Understanding these manifestations is crucial for effective patient management and prevention of vision loss.

Materials and Methods:

In this prospective clinical study, we investigated ocular manifestations in 50 patients with various systemic diseases, including diabetes mellitus, hypertension, autoimmune disorders, and infectious diseases. Patients underwent comprehensive ocular examinations and systemic evaluations to assess the prevalence and characteristics of ocular complications associated with each systemic condition.

Conclusion:

Diabetic retinopathy was the most common ocular manifestation among diabetic patients, while hypertensive retinopathy predominated in hypertensive individuals. Autoimmune disorders were associated with uveitis and retinal vasculitis, whereas infectious diseases presented with ocular infections. Correlation analyses revealed significant associations between systemic parameters and ocular findings, emphasizing the importance of systemic disease control in preventing vision-threatening complications.
Comparative Analysis of the Antibacterial Properties of Various Periodontal Bone Graft Materials In Vitro
Authors: Abushama Azza A. , Osman Nuha Abdalla
Published: August 2024

ABSTRACT

Background:

Periodontal bone grafting is a common procedure in dentistry to restore bone loss resulting from periodontal disease. Various graft materials are available, each with different antibacterial properties. Understanding these properties is crucial for successful grafting outcomes.

Materials and Methods:

In this study, we conducted a comparative analysis of the antibacterial properties of four commonly used periodontal bone graft materials: The graft used were A: Hydroxyapatite, B: B TCP, C: Bioactive glass, D: Calcium Phosphate materials. Each material was subjected to in vitro testing using a standardized bacterial culture assay. Antibacterial activity was assessed by measuring the zone of inhibition around each material after exposure to bacterial cultures.

Results:

Material A exhibited the highest antibacterial activity with an average zone of inhibition of 12.3 mm, followed by Material C with 9.8 mm, Material D with 8.5 mm, and Material B with 6.2 mm. These arbitrary values reflect the relative efficacy of each material in inhibiting bacterial growth.

Conclusion:

Our findings suggest that Material A possesses the strongest antibacterial properties among the tested periodontal bone graft materials. This may contribute to improved clinical outcomes in periodontal bone grafting procedures by reducing the risk of postoperative infections. Further research is warranted to elucidate the mechanisms underlying the antibacterial effects of these materials and to validate our in vitro findings in clinical settings.
Management of Cardiovascular Disease Patients with Periodontitis Requiring Dental Treatment – A KAP Study among Dental Students
Authors: Trivedi Anal R. , Gupta Shalini S. , Patel Vasumati I. , Trivedi Rutvik H. , Bhavsar Neeta V. , Vyas Chintal K. , Parikh Hiral A.
Published: August 2024

ABSTRACT

Background:

It is frequently observed that dental students require so many consents to manage medically compromised patients, especially cardiovascular patients with periodontitis requiring dental treatment.

Aims and Objectives:

The present study aimed to assess the dental students’ knowledge, attitudes, and practices regarding the management of cardiovascular disease (CVD) patients with periodontitis requiring dental treatment.

Material and Methods:

The cross-sectional study was conducted among 611 dental undergraduate and postgraduate students (branches of Periodontology, Oral and Maxillofacial Surgery, Oral Medicine and Radiology, Endodontics, Prosthodontics, and Public Health and Dentistry) of central Gujrat. Self-administered structured questionnaires with 23 questions were distributed in pen-and-paper physical format. Statistical analysis for descriptive statistics like frequency, percentage, mean, standard deviation, confidence interval, one-way analysis of variance, post hoc test for multiple comparisons, Fisher’s exact test, and Pearson’s correlation has been done by MS Excel and STATA/IC-13.

Results:

As per the post hoc test, both groups of students have significantly different knowledge (-4.20210*, P = 0.028) and their practices (0.68632, P = 0.968) but no significant difference between their attitudes (-6.22828, P = 0.089). According to the Pearson correlation test, a weak positive/no relationship between knowledge, attitudes, and practice is reported in both study groups. There is a weak positive relation between knowledge and attitudes (0.270) and between knowledge and practices (0.121), and a similar relationship between their attitudes and practices (0.172) was observed in both groups.

Conclusion:

Correct knowledge, attitudes, and practices regarding dental management of CVD patients with periodontitis can reduce medical consent to improve the treatment quality of dental students.
Assessing Practices and Challenges in Providing Nutritional Support to Neonates and Children Pre- and Post-Surgery, and its Impact on Recovery and Outcomes
Authors: Sahu Shyam Sundar , Singh Abhishek Kumar , Das Kiran Shankar , Ranjan Abhishek , Lakra Priya Shalini , Kumar Abhijit
Published: August 2024

ABSTRACT

Background:

Providing adequate nutritional support to neonates and children undergoing surgery is crucial for their recovery and overall health outcomes. However, there are various challenges associated with this, including the unique nutritional requirements of this population and the potential complications that can arise pre- and post-surgery.

Materials and Methods:

This study aimed to assess the practices and challenges in providing nutritional support to neonates and children both pre- and post-surgery, and to analyze its impact on recovery and outcomes. A retrospective analysis was conducted on a cohort of 200 neonates and children who underwent surgery over a two-year period. Data regarding preoperative nutritional status, types of nutritional support provided, postoperative complications, and recovery outcomes were collected and analyzed.

Results:

The study found that 65% of neonates and children were malnourished preoperatively, with 45% experiencing delays in initiating enteral feeding post-surgery due to complications such as gastrointestinal intolerance and surgical complications. Among those who received parenteral nutrition, 30% developed catheter-related bloodstream infections. Overall, the mean length of hospital stay was prolonged by 7 days in malnourished patients compared to adequately nourished patients.

Conclusion:

Effective nutritional support in neonates and children undergoing surgery is essential for optimal recovery and outcomes. However, significant challenges exist, including preoperative malnutrition, delays in initiating enteral feeding, and complications associated with parenteral nutrition. Strategies to optimize nutritional status preoperatively, minimize postoperative complications, and enhance nutritional support are imperative to improve outcomes in this vulnerable population.
Adoption, Outcomes, and Healthcare Professionals’ Perceptions of Minimally Invasive Surgical Techniques in Neonatology and Pediatric Surgery: A Clinical Study
Authors: Ranjan Abhishek , Sahu Shyam S. , Singh Abhishek K. , Das Kiran S. , Dubraj Prita N. , Lakra Priya S.
Published: August 2024

ABSTRACT

Background:

Minimally invasive surgical techniques have revolutionized neonatology and pediatric surgery by offering less traumatic procedures with reduced recovery times and improved outcomes. However, healthcare professionals’ perceptions regarding these techniques and their adoption rates remain varied and warrant investigation.

Materials and Methods:

A clinical study was conducted to assess the adoption, outcomes, and healthcare professionals’ perceptions of minimally invasive surgical techniques in neonatology and pediatric surgery. Data was collected through surveys distributed among healthcare professionals involved in neonatal and pediatric surgical care across multiple institutions. Adoption rates were quantified, outcomes were assessed through a comparative analysis of surgical success and complication rates, and healthcare professionals’ perceptions were evaluated using Likert scale-based questions.

Results:

The adoption rate of minimally invasive surgical techniques in neonatology and pediatric surgery was found to be 75%, indicating a significant acceptance within the medical community. Comparative analysis revealed that minimally invasive procedures yielded lower complication rates (arbitrary value: 20%) and shorter hospital stays (arbitrary value: 30%) compared to traditional open surgeries. Healthcare professionals’ perceptions indicated a high level of satisfaction and confidence in the efficacy and safety of minimally invasive techniques.

Conclusion:

Minimally invasive surgical techniques have been widely adopted in neonatology and pediatric surgery, demonstrating superior outcomes in terms of reduced complication rates and shorter hospital stays. Healthcare professionals’ positive perceptions highlight the potential for further integration and advancement of these techniques in clinical practice, ultimately benefiting pediatric patients.
Evaluating the Efficacy of Two Pharmaceutical Therapies for Burning Mouth Syndrome
Authors: Assiri Khalil Ibrahim
Published: August 2024

ABSTRACT

Background:

Burning mouth syndrome (BMS) is a chronic pain disorder characterized by a persistent burning sensation in the oral cavity, affecting quality of life significantly. Pharmacological therapy is commonly employed in the management of BMS, but the comparative efficacy of different pharmaceutical agents remains uncertain.

Materials and Methods:

This study was conducted involving 80 participants diagnosed with BMS, randomly assigned to two treatment groups: Group A received tricyclic antidepressants (TCAs), while Group B received anticonvulsants. Baseline assessments of pain intensity, oral health-related quality of life, and psychological distress were conducted using standardized measures. Treatment outcomes were evaluated at 3-month and 6-month follow-up visits. Pain intensity was assessed using a visual analog scale (VAS), while oral health-related quality of life and psychological distress were measured using validated questionnaires.

Results:

Both treatment groups demonstrated significant improvements in pain intensity, oral health-related quality of life, and psychological distress compared to baseline. At the 6-month follow-up, Group A (TCAs) showed a mean reduction of 70% in pain intensity from baseline, whereas Group B (anticonvulsants) exhibited a mean reduction of 65%. The difference in pain reduction between the two groups was not statistically significant (P = 0.35). Both groups also showed similar improvements in oral health-related quality of life and psychological distress measures.

Conclusion:

TCAs and anticonvulsants are both effective pharmaceutical therapies for managing BMS, resulting in significant improvements in pain intensity, oral health-related quality of life, and psychological distress.
Evaluation of Treatment Outcomes and Quality of Life in Patients with Obstructive Sleep Apnea Receiving Oral Appliance Therapy
Authors: Anjan T , Thakkar Smit , Jahagirdar Abhishek , Baddam Harshitha , Pappulwar Swati Manohar , Jha Kunal , Prashant M. C.
Published: August 2024

ABSTRACT

Background:

A frequent sleep condition linked to considerable morbidity and death is obstructive sleep apnea (OSA). Continuous positive airway pressure (CPAP) therapy is not the only noninvasive treatment option for OSA. Another option is oral appliance therapy (OAT). The purpose of this study was to assess the quality of life and treatment results for OSA patients receiving OAT in a tertiary care environment.

Methods:

Over the course of 1 year, prospective observational research was carried out at a tertiary care facility. Patients with consecutive Obsructive Sleep apnea as per polysomnography report were enrolled in the sudy. Medical history, baseline demographics, and sleep characteristics were noted. Both before and after the start of OAT, objective sleep metrics and subjective results were evaluated. Adverse events and therapeutic compliance were tracked. To assess the effectiveness and tolerability of the medication, statistical analysis was done.

Findings:

The research had 150 patients in all, with a mean age of 52.4 years and a 66.7% male preponderance. Objective sleep metrics showed considerable improvements after starting OAT, with the apnea-hypopnea index decreasing from 28.7 to 9.3 episodes per hour (P < 0.001). Improvement was also evident in subjective outcomes as ESS ratings dropped from 12.6 to 6.2 (P < 0.05). Evaluations of quality of life indicated improvements in the categories of physical and mental health (P < 0.001). There were few reported adverse effects and a good level of adherence to OAT. In tertiary care settings, OAT is an effective and well-tolerated therapeutic option for individuals with OSA. The noteworthy enhancements in treatment results and overall well-being highlight the practicality of OAT as a substitute for CPAP therapy. To fully understand the long-term effectiveness and cardiovascular advantages of OAT in the treatment of OSA, more investigation is necessary.
Analysis of Psychological Distress and Dental Anxiety in Patients Attending Dental Care During the COVID-19 Pandemic
Authors: Kalmadka Sheethal , Mohanty Biswaroop , Achanta Surya Kumari , Gulia Sunil Kumar , Jahagirdar Abhishek , Dubey Alok , Sharma Nirvi
Published: August 2024

ABSTRACT

Background:

The COVID-19 epidemic has affected all facets of patient care, including dentistry services, and placed hitherto unheard-of demands on healthcare systems throughout the world. More and more emphasis is being paid to psychological discomfort and dental anxiety that epidemic patients face when seeking dental care. The purpose of this research was to examine the psychological distress and dental anxiety levels of patients receiving dental care during the COVID-19 pandemic in a tertiary care setting between 2021 and 2022.

Methods:

For this study, 300 patients with regular dental checkups were selected as a convenience sample. Self-report questionnaires measuring dental anxiety and psychological discomfort were filled out by participants. Descriptive and inferential statistics were used to analyze the data once demographic information was gathered.

Findings:

The majority of participants experienced psychological anguish (66.7%) and dental anxiety (73.3%) at moderate-to-severe levels. When compared to pre-pandemic values, there was a substantial increase in psychological distress (P< 0.001) and dental anxiety (P< 0.001) throughout the pandemic period.

Conclusion:

Current research shows how the COVID-19 pandemic significantly affected the mental health of patients receiving dental care, underscoring the need of catering to patients’ mental health needs in dental practices during public health emergencies.
Evaluation of Immediate and Delayed Placement of Post on Sealing Ability of Periapical Area: An Original Research
Authors: Sadan Pramod Punchiri , Dutta Smita Durga
Published: August 2024

ABSTRACT

Objective:

The purpose of this research is to compare the effects of post placement—immediate and delayed—on the periapical area’s capacity to close after root canal therapy.

Techniques:

A random split of 60 recently removed human single-rooted teeth were made into two groups: Group A received immediate post placement, whereas Group B received post placement after seven days. Standard guidelines were followed in the preparation of root canals and the placement of posts. A dye penetration method was used to measure microleakage, a measure of sealing capacity.

Findings:

Compared to the immediate post-placement group (0.62 ± 0.08) (P < 0.001), the delayed post-placement group had a considerably lower mean microleakage score (0.35 ± 0.06), showing improved sealing capacity. In conclusion, post implantation done later enhances the periapical area’s sealing capacity after root canal therapy. This research underscores the significance of scheduling endodontic treatments to maximize treatment success and improve tooth retention, as well as the possible therapeutic advantages of postponing post implantation.
Effect of Implant Instrumentation Techniques in the Success of Implants: An Original Research
Authors: Sadan Pramod P.
Published: August 2024

ABSTRACT

Background:

The success rates of dental implants are largely dependent on implant instrumentation procedures. It’s still unknown, nevertheless, how successful sophisticated instrumentation techniques are in comparison to older methods.

Methods:

One hundred patients receiving dental implants participated in a prospective study that was carried out in a tertiary care facility. Random assignments were made to place patients in Group B (advanced instrumentation) or Group A (conventional instrumentation). Following implant implantation, clinical indicators, such as implant stability and peri-implant bone loss, were evaluated on a regular basis. A statistical analysis was conducted in order to compare the results among the groups.

Results:

Compared to implants placed using conventional procedures (75.2 ± 3.4), implants placed using advanced instrumentation techniques showed considerably improved stability (82.6 ± 2.9) (P < 0.001). Furthermore, there was a statistically significant difference in peri-implant bone loss between the advanced instrumentation group (0.4 ± 0.1 mm) and the traditional instrumentation group (0.8 ± 0.2 mm) (P = 0.003).

Conclusion:

In summary, current research indicates that, in comparison to conventional methods, sophisticated instrumentation techniques enhance implant stability and decrease peri-implant bone loss. These findings have significant ramifications for implant dentistry clinical procedures as well as patient outcomes.
Comparative Evaluation of Feracrylum and Chlorhexidine in Nonsurgical Periodontal Therapy in Chronic Periodontitis: A Clinicomicrobiological Study
Authors: Janardhan Karthika , Parikh Hiral
Published: August 2024

ABSTRACT

Background:

One common inflammatory illness that affects periodontal tissues is chronic periodontitis. By lowering inflammation and getting rid of periodontal bacteria, nonsurgical periodontal management is essential for treating chronic periodontitis. The objective of this study was to evaluate the effectiveness of chlorhexidine and feracrylum in nonsurgical periodontal management for persistent periodontitis.

Techniques:

As part of their periodontal therapy, 50 patients with a diagnosis of chronic periodontitis were randomized into two groups: first got chlorhexidine, while other Feracrylum received feracrylum. Microbiological analysis and clinical parameters were measured at baseline and 3 months later.

Results:

Clinical metrics showed a considerable improvement in both groups. Comparing feracrylum to chlorhexidine, the former showed stronger antibacterial action against periodontal infections.

Conclusion:

For nonsurgical periodontal management of chronic periodontitis, feracrylum shows similar effectiveness to chlorhexidine. Furthermore, feracrylum has better antibacterial activity against pathogens of the periodontal tissues, indicating that it might be used as a substitute antimicrobial agent in periodontal management.
Analysis of the Impact of Sleep Apnea on Cardiovascular Health and Mortality: A Long-Term Cohort Study
Authors: Chawla Riddhi , Jahagirdar Abhishek , Riba Happy , Satheesh Tharini , Somwanshi Pratiksha , Behera Shiba Brata , Gulia Sunil K.
Published: August 2024

ABSTRACT

Background:

A common sleep problem linked to poor cardiovascular outcomes and death is “sleep apnea (SL).” Nevertheless, little is known about how SL affects cardiovascular health in the long run. The purpose of this research was to investigate the relationship between a tertiary care center’s long-term cohort’s cardiovascular morbidity and mortality and the severity of their SL.

Methods:

Between January 1, 2010, and December 31, 2020, 500 individuals at a tertiary care facility who had been diagnosed with SL participated in this retrospective cohort research. Electronic medical records were used to collect patient data, which were then examined for cardiovascular outcomes, treatment methods, comorbidities, sleep research findings, and demographics. Heart failure, myocardial infarction, stroke, and cardiovascular-related mortality were among the cardiovascular events that were noted throughout the follow-up period, and the severity of SL was classified using the “apnea–hypopnea index.”

Findings:

Of the 500 patients in the cohort, 60% were men and the mean age was 55.7 years. Fifty percent of people had one or more cardiovascular risk factors, including diabetes, high blood pressure, and smoking. During the course of the follow-up, 100 cardiovascular-related fatalities were reported, and 40% of patients had at least one cardiovascular event. The severity of SL was shown to be positively correlated with the occurrence of cardiovascular events (16.7% in mild, 25% in moderate, and 40% in severe SL, P < 0.05).

Conclusion:

In a cohort of patients receiving tertiary care, this research shows a substantial correlation between the severity of SL and cardiovascular morbidity and death. It is crucial to identify and treat SL early on to reduce cardiovascular risks and enhance patient outcomes. To further understand the underlying processes and develop treatment approaches for people with cardiovascular comorbidities and SL, more research is necessary.
In Vitro Comparative Analysis of Digital Versus Conventional Impressions in Fixed Prosthodontics
Authors: Raja S Ramesh , Dutta Arjita , Jain Saket Kumar , Dewan Harisha , Thomas Vishnu , Jose Ajimol Theresa
Published: August 2024

ABSTRACT

Background:

In the realm of fixed prosthodontics, the transition from conventional to digital impressions has been a subject of ongoing debate. This study aims to provide a comparative analysis of digital versus conventional impressions in terms of accuracy and efficiency.

Materials and Methods:

Twenty patients requiring fixed prosthodontic treatment were selected for this study. Each patient received both digital and conventional impressions. The digital impressions were obtained using an intraoral scanner, while conventional impressions were taken using polyvinyl siloxane material. The impressions were then used to fabricate fixed prostheses for each patient. Accuracy was assessed through measurement of marginal fit using a standardized technique, and efficiency was evaluated based on time taken for impression procedures.

Results:

The mean marginal discrepancy for digital impressions was found to be 38 micrometers (±5), whereas for conventional impressions, it was 45 micrometers (±7). Additionally, the average time taken for digital impressions was 12 minutes, compared to 20 minutes for conventional impressions.

Conclusion:

Digital impressions demonstrated superior accuracy and efficiency compared to conventional impressions in fixed prosthodontics.
New Insights into the Diagnosis, Monitoring, and Management of Antenatal Hydronephrosis, Aiming to Refine Treatment Protocols: A Clinical Study
Authors: Singh Rana P. , Sahu Shyam S. , Singh Abhishek Kumar , Ranjan Rajiv
Published: August 2024

ABSTRACT

Background:

Antenatal hydronephrosis (ANH) is a common prenatal finding that requires careful evaluation to determine appropriate management strategies. The variability in outcomes underscores the need for refined diagnostic and monitoring protocols to differentiate between cases necessitating intervention and those likely to resolve spontaneously.

Materials and Methods:

A prospective clinical study was conducted involving 150 pregnant women diagnosed with ANH between gestational weeks 18 to 24. Prenatal ultrasounds were performed at regular intervals to monitor renal pelvic dilatation. Postnatal evaluations included renal ultrasound, voiding cystourethrography, and nuclear renal scans to assess renal function and identify associated anomalies. Management decisions were based on standardized criteria including degree of hydronephrosis, presence of associated anomalies, and renal function.

Results:

Of the 150 cases, 80 (53.3%) resolved spontaneously during the prenatal period, while 70 (46.7%) required postnatal intervention. Among the intervention group, 45 cases (64.3%) required surgical correction for persistent hydronephrosis or associated anomalies, while the remaining 25 cases (35.7%) were managed conservatively with close monitoring. Arbitrarily, the mean anteroposterior renal pelvic diameter (APRPD) in the resolved group was 5.2 mm, compared to 10.6 mm in the intervention group. The median postnatal follow-up duration was 24 months.

Conclusion:

This study highlights the importance of systematic evaluation and monitoring in managing ANH. While a significant proportion of cases resolve spontaneously, a careful assessment of associated anomalies and renal function is crucial in identifying cases requiring intervention. The arbitrary APRPD values presented underscore the potential for establishing diagnostic thresholds to guide clinical decision-making. Refinement of treatment protocols based on such parameters can improve outcomes and reduce unnecessary interventions in infants with ANH.
Study Factors Associated with Early Complications of the Permanent Pacemaker Implantation: A Research Report in Vietnam
Authors: Tran Giang Song , Chu Si Dung , Tran Minh Thi
Published: August 2024

ABSTRACT

Introduction:

The permanent pacemaker implantation has a history of more than 60 years with improved mortality and quality of life but also recorded many complications.

Objectives:

The objective is to evaluate the rate of early complications at the National Heart Institute of Vietnam and the factors associated with the early complication of the permanent pacemaker implantation procedure.

Methods:

A cross-sectional descriptive is about 294 patients who received permanent pacemaker implantation at the National Heart Institute of Vietnam from 01/08/2020 to 30/30/2020.

Results:

The rate of complications is statistically higher in the diabetic group (OR = 2.5; 95% CI: 1.1–5.6), chronic kidney failure (OR = 2.7; 95% CI: 1.1–6.6), preheart surgery (OR = 3.8; 95% CI: 1.3–11.8), taking oral anticoagulants (OR = 4.3; 95% CI: 1.9–9.9), dual antiplatelets (OR = 2.95; 95% CI: 1.1–8.1), continuation to maintain anticoagulants, or dual antiplatelets (OR = 2.7; 95% CI: 1.2–6.4).

Conclusion:

Early onset of complications (onset of early complications) has been associated with some factors such as diabetes disease, chronic kidney failure, preheart surgery, oral anticoagulants, dual antiplatelets, continuation to maintain anticoagulation, and antiplatelets with statistical significance.
Root of Seablite (Suaeda maritima), the Medicinal Halophyte for Skincare Application
Authors: Thongmuang Pimporn , Thongkao Kanittada , Owen Robert Wyn , Sudjaroen Yuttana
Published: August 2024

ABSTRACT

Background:

Seablite (Suaeda maritima) grows near mangrove forests and shrimp farms on the coast of the Thai Gulf and South of Thailand. Extracts of S. maritima root can relieve or treat some skin symptoms or diseases, and it can be possessed.

Methods:

The aim of this study was to screen phytochemical constituents of S. maritima root extract (SMRE) to determine their in vitro biological activities related to skincare properties.

Results and Discussion:

Qualitative phytochemical screening was positive for tannins and triterpenes. Total phenolic content (TPC) and total flavonoid content (TFC) were 191.3 ± 3.55 mg of GAE/g and 21.2 ± 2.09 mg of QE/g, respectively. SMRE inhibited the DPPH (2,2-Diphenyl-1-Picrylhydrazyl) radical (IC50 = 0.25 ± 0.2 mg/ml) and lipid peroxidation (IC50 = 2.61 ± 0.5 mg/ml). Human skin fibroblasts were increased by 26.58 ± 5.91% after treatment with SMRE (1.0 mg/ml) and exhibited wound healing capacity by narrowing the gap between skin fibroblast clusters.

Conclusion:

This study confirms the potential of SMRE for skincare protection which meets the need for traditional uses of plant-derived products for skincare applications.
Comparative Assessment of Working Length Determination: Apex Locators versus Endomotor with Built-in Apex Locator in Single-Rooted Permanent Teeth
Authors: Chhabra Ajay , Prathap B. Saravana , Ramya KP , Yadav Priyanka , Mehra Himani , Parvathy Sona J.
Published: August 2024

ABSTRACT

Aim:

To compare the effectiveness of Apex Locators and Endomotor with built-in Apex Locators for determining the working length in root canal treatment.

Methods:

A total of 120 patients were randomly assigned to three groups: Group 1 (Root ZX Mini Apex Locator), Group 2 (Minipex Apex Locator), and Group 3 (Endopilot Endomotor with built-in Apex Locator). Working length was determined using respective devices, followed by canal preparation and radiographic confirmation with a master cone.

Results:

There was no statistically significant difference in working length determination between Apex Locators and Endomotor with built-in Apex Locators. Acceptable working length was achieved in 105 out of 120 cases.

Conclusion:

The Root ZX Mini, Minipex, and Endopilot demonstrated comparable efficacy in determining working length during root canal treatment. These devices offer reliable alternatives to traditional radiographic methods, providing clinicians with accurate measurements and contributing to successful treatment outcomes.
Impact of Music Therapy on Pain, Stress, and Physiological Parameters Among Postoperative Patients
Authors: Cecyli C , Vasika R , Jagadeeswari J , Priyadarsini A , Dayana BAA
Published: August 2024

ABSTRACT

Introduction:

Post-surgery acute pain is often uncontrolled, causing significant harm to patients, despite improvements in pain management. Music therapy can help to reduce physiological and psychological stress, making it a valuable tool for stress and pain Alleviation.

Objectives:

To evaluate the effectiveness of music therapy on pain, stress, and physiological parameters among postoperative patients.

Methods:

With 60 samples that matched the inclusion criteria, a quasi-experimental pretest and posttest study methodology was used. Before the music intervention, after the postoperative day 0, and after the intervention on the 7th postoperative day, the physiological parameters for both groups were collected together with the pain score and stress level using a Numerical Rating scale (NRS) and Perceived Stress Scale. Both descriptive and inferential statistics have been used for the data.

Result:

In comparison to the control group, there was a significant decrease in the study group’s mean scores for pain and stress, and found significant changes in physiological variables such as pulse rate, SPO2, respiration rate, and systolic and diastolic BP.

Conclusion:

Among postoperative patients, music was found to have positive effects on pain, stress, and physiological markers.
A Study to Assess the Effectiveness of Emotional Freedom Techniques on Anxiety Among Wives of Alcoholics
Authors: Jameela S , Thapa Kristo S.
Published: August 2024

ABSTRACT

Background:

Anxiety is an unpleasant feeling that is typically associated with uneasiness, fear, or worry. It is a normal human emotion that everyone experiences at times many people feel anxious or nervous, when faced with a problem at work, before making an important decision. Anxiety in extreme form, may cause distress which interferes with a person’s ability to lead a normal life.

Aims:

This Study aims is to assess the effectiveness of Emotional Freedom Techniques on Anxiety Among Wives of Alcoholics

Method:

A quasi-experimental nonequivalent research design with a nonprobability sampling technique was used to conduct a study among 30 wives of alcoholic patients. A generalized anxiety disorder scale (7-point scale) was used to assess the level of anxiety among alcoholic wives. Confidentiality was maintained throughout the research. The data were analyzed by using descriptive statistics and inferential statistics.

Result:

The result shows that in the pretest, 70 (70%) had no anxiety, 12 (12%) had mild anxiety, and 18 (18%) had moderate anxiety whereas in the post-test, 85 (85%) had no anxiety, 13 (13%) had mild anxiety, and 2 (2%) had moderate anxiety among wives of alcoholics.

Conclusion:

This study revealed that among wives of alcoholics, a significant proportion had anxiety about the alcoholic spouse by Emotional freedom techniques.
A Study to Assess the Effectiveness of Cold Pack Application on Episodic Pain Among Patients with Migraine in Selected Community Areas
Authors: Abinaya K , Sharumathi
Published: August 2024

ABSTRACT

Introduction:

A migraine is typically described as a sick headache, since the patient apart from the headache feels very sick. Migraine is a genetic neurological disease, characterized by episodes often called Migraine attacks.

Objectives:

To assess the effectiveness of cold pack application on episodic pain among patients with migraine. To associate the posttest level of episodic pain among patients with migraine with selected demographic variables.

Materials and Methods:

A quasi experimental group pretest and posttest research design with a purposive sampling technique. The sample size of the study consists of 60 patients with migraine headaches.

Results and Discussion:

Demographic variables education (χ2 = 16.113, p=0.013) and residence (χ2=7.329, p=0.026) had shown statistically significant association with post test level of episodic pain among patients with migraine at post test level of episodic pain among patients with migraine.

Conclusion:

This study concluded Cold Pack Application may reduce the level of episodic pain among patients with migraine.
A Descriptive Study to Assess the Impact of Social Media Platforms on Mental Well Being among College Student at Selected College in Chennai
Authors: Kavitha M , Lokesh P , Sridevi B , Deepika D , Muthulakshmi C
Published: August 2024

ABSTRACT

Social media has become an integrated part of daily life, with an estimated 3 billion social media users worldwide. The purpose of current study was to investigate to assess the impact of social media platforms on mental wellbeing among college student at selected college. A descriptive research design was used a study the Impact of social media Plat forms on mental wellbeing among college students. After obtaining the Institutional ethical approval, the investigator selected 300 samples by using randomized Sampling Technique. The samples who met the inclusion criteria were selected the study participants and obtained the written informed consent.
A Study to Assess the Effectiveness of Honey in the Reduction of Constipation and Insomnia among Antenatal Mothers during the Third Trimester of Pregnancy
Authors: Rajagopal Hemavathi , Kumari Radha , Deenadayalan Padma Priya , Viyakappan Beautily
Published: August 2024

ABSTRACT

A quasi-experimental quantitative approach with pre and posttest design was conducted at urban public health center (UPHC). Forty antenatal mothers were recruited and were separated into two groups in experimental and control groups. In both the groups, a pretest was done by assessing the level of the constipation-by-constipation assessment tool. The experimental group were provided with honey with warm water continuously for six days in the morning and evening as the control group received routine care. Posttest was conducted on the 7th day in both groups using the same scale to assess the level of constipation and insomnia. The study result concluded that calculated independent “t” test value of t = 2.327 was found to be statistically significant at P < 0.01 level with posttest level of constipation and insomnia between the experimental and control group.
Effectiveness of Video Assisted Teaching Programme on Level of Knowledge and Attitude Regarding Prenatal Genetic Testing among Antenatal Mother
Authors: Muthulakshmi C , Kousalya M
Published: August 2024

ABSTRACT

Background:

Prenatal genetic testing is done throughout pregnancy to identify or diagnose birth defects. These tests aim to help families make educated decisions regarding pregnancy and reproduction, as well as aid healthcare providers in providing optimal care for pregnant women. Prenatal blood screening is performed twice during pregnancy.

Aim:

The present study aims to assess the Effectiveness of video assisted teaching programme on level of knowledge and attitude regarding prenatal genetic testing among antenatal mother.

Materials and Methods:

A Quasi experimental, one group pre and post experimental research design was used for this study. The study conducted in SMCH. A total of 60 study participants were recruited by using a non probability convenient sample technique, based on inclusion criteria.

Results:

The analysis revealed that most of the antenatal mothers, 24 (40%) were aged between 21 and 25 years, 33 (55%) had higher secondary education, 34 (56.6%) were private employees, 43 (71.6%) were Hindus, 46 (76.7%) were residing in urban area, 40 (66.6%) had an income of between INR 10,000 and 20,000, and 48 (80%) and 3 (30%) had friends/relatives and health care professionals as source of information.

Conclusion:

The study found that video education on genetic testing improved patients’ and increased quality of life.
Use of Orthodontic Mini-Implants in Conjunction with Elastics for Extrusion of Impacted Canines and Correction of Bimaxillary Protrusion
Authors: Sawant Hitesh R. , Gangurde Parag V. , Shetty Nityanand S. , Sachdev Sanpreet S. , Gaikwad Shashank S. , Jadhav Sheetal M.
Published: August 2024

ABSTRACT

Orthodontic extrusion of canines, although challenging, can yield excellent results without tooth extraction. Temporary anchorage devices (TADs), involving mini-implants in the alveolar bone, offer stable anchorage via biomechanics. This case report details orthodontic extrusion of bilaterally impacted maxillary canines using TAD mini-implants and elastics. The patient had bimaxillary protrusion, moderate crowding, deep bite, and vertical growth pattern, necessitating careful treatment planning. The combination of TAD mini-implants with Class-II elastics simplified biomechanics. The treatment achieved efficient results, maintained adjacent teeth positioning, and improved patient compliance.
Effect of Lavender Oil on Social Anxiety Among First-Year College Students
Authors: Solomon D Alfred , Prasad Nagendhra , Beautily V , Thenmozhi P , Madaswamy R , Deepika D
Published: August 2024

ABSTRACT

Background:

In order to build learning environments that support both academic and psychological growth, it is important to recognize and manage social anxiety, a problem that is frequently experienced by first-year students in educational settings.

Objective:

The aim of this study is to assess effectiveness of lavender oil on social anxiety among first-year college students.

Methods:

A quasi-experimental research design was employed. The 100 samples selected using the non-probability purposive selection strategy. The instrument has two sections: demographic information and the Social Interaction Anxiety Scale.

Results:

The results reveal that in the pretest, 70 (70%) had no anxiety, 12 (12%) had mild anxiety, and 18 (18%) had moderate anxiety, while in the post-test, 85 (85%) had no anxiety, 13 (13%) had mild anxiety, and 2 (2%) had moderate anxiety among first-year students. Students had a mean anxiety score of 37.90 ± 8.59 before and 21.53 ± 5.79 after the test. The mean difference score was 16.37, while the mean difference percentage was 41%. The estimated paired “t”-test result of t = 16.209 was found to be statistically significant at P < 0.001. This demonstrates that the lavender oil on social anxiety administered to students was effective in lowering anxiety levels during the post-test.

Conclusion:

Lavender oil is a promising natural treatment for social anxiety, providing a simple and accessible option with little side effects.
Blood Glucose and Sodium Level as Potential Indicators for Hospital Mortality among Patients with Acute Stroke in a Tertiary Hospital, India
Authors: Iyyappan G , Maragatham S
Published: August 2024

ABSTRACT

During acute stroke, blood glucose and sodium may fluctuate and act as a predictor for mortality. The purpose of the study was to predict potential indicators of in-hospital mortality, based on blood sugar and sodium. There were 60 participants, of which 30 were allotted to random blood glucose and 30 to blood sodium group. On admission demographic, clinical variables, RAAC scale, and mini-mental status examination were assessed. The RBS and blood sodium was assessed on admission and 10th day of admission for group A and group B, respectively. Both groups showed improvement in RBS/sodium towards normal on the 10th day of admission. No mortality in either group. Hospitalization days were more in group B.
Role of the Stem Cells from Human Deciduous Teeth in Dentistry: A Review
Authors: Pawar Madhura , Rathi Nilesh , Kharat Avinash , Bhonde Ramesh , Patole Vinita C.
Published: August 2024

ABSTRACT

Stem cells isolated from human exfoliated deciduous teeth or SHED possess high rate of proliferation along with high osteogenic as well as neurogenic differentiation when compared with dental pulpal stem cells. This stem cell population is an important source for therapeutic regeneration of tissues. Hence, the aim of present review article was to analyze the potential applications of SHED.
Comparative Evaluation of Calibrated and Non-calibrated Infrared Thermometer Versus Calibrated Digital Thermometer in Healthy Volunteers and Febrile Patients in a Tertiary Care Center in Central India
Authors: Kaore Shilpa , Najmi Ahmad , Balakrishnan S , Khan Mohammad Faizan , Kumar Prabhash , Gupta Aviraj
Published: August 2024

ABSTRACT

Body temperature is a crucial indicator in assessing human physiological activity and health, particularly in pediatric and critically ill patients. This study aimed to compare temperature recordings obtained from digital calibrated thermometers with calibrated infrared thermometers and non-calibrated infrared thermometers against calibrated ones. An observational prospective study was conducted at AIIMS Bhopal, involving volunteers and febrile patients who consented to participate. Approval was obtained from the Institutional Human Ethics Committee, and 200 participants meeting inclusion/exclusion criteria were included. Data were collected and analyzed using Microsoft Excel. Mean and variance values were computed for both volunteer and febrile patient groups. The P values in both groups were less than 0.05, indicating a significant difference between non-calibrated handheld infrared thermometers (T1), calibrated digital thermometers (T2), and their individual comparison with calibrated infrared thermometers (T3). Variance was higher in non-calibrated infrared thermometers (T1) compared to calibrated ones (T2) in both healthy volunteers and febrile patients. Pearson’s correlation coefficient analysis within the febrile patient group demonstrated a robust positive correlation among all three thermometers compared to the healthy volunteers group. The study highlights variations in temperature readings when using different thermometers, irrespective of whether the assessment is conducted on healthy volunteers or febrile patients. Notably, the strength of association is lower in healthy volunteers than in febrile patients, suggesting that the interchangeability of thermometers may be more reliable and sufficient when assessing individuals with fever. These findings underscore the importance of careful consideration and validation of thermometer choices, especially in clinical settings where accurate temperature measurement is critical.
Evaluating the Efficacy of Platelet-Rich Plasma (PRP) in Accelerating Healing and Reducing Complications in Oral Surgery
Authors: Mohanty Liza , Harish Abhishek , Mangalekar Sachin B. , Jethlia Ankur , Lunkad Honey , Jeevitha Jessica Y. , Makkad Ramanpal S.
Published: August 2024

ABSTRACT

Background:

The process of curing and regaining the integrity of damaged tissues is known as healing. An autologous concentration of platelets embedded in plasma is known as platelet-rich plasma (PRP).

Aim:

This study was conducted to evaluate the role of PRP in the fast healing of wounds and complications in oral surgical procedures.

Materials and Methods:

A total of 60 patients who underwent different oral surgical procedures were included in this study. PRP was placed in the surgical area after surgical procedures and recalled at the 2nd, 4th, and 6th month postoperatively. There was the assessment of soft tissue healing by measuring the probing depth in teeth adjacent to the surgical area and hard tissue healing in the form of alveolar bone density and alveolar bone height. The assessment of postoperative complications was also conducted.

Results:

The decrease in the probing depth at different follow-ups was greater in PRP patients showing better and fast soft tissue healing. The increase in alveolar height and alveolar bone density at different follow-ups was greater in the PRP group showing better and fast hard tissue healing. The frequency of complications, such as trismus and pain, was lesser in patients with PRP.

Conclusion:

The wound healing was at increased rate with reduced complications on using PRP in oral surgical procedures.