bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from Use of [11C]Choline PET-CT as a Noninvasive Method for Detecting Pelvic Lymph Node Status from Prostate Cancer and Relationship with Choline Kinase Expression
Authors: Contractor Kaiyumars , Challapalli Amarnath , Barwick Tara , Winkler Mathias , Hellawell Giles , Hazell Steve , Tomasi Giampaolo , Al-Nahhas Adil , Mapelli Paola , Kenny Laura M. , Tadrous Paul , Coombes R. Charles , Aboagye Eric O. , Mangar Stephen
Published: April 2023

PDF file - 132K
Supplementary Table 2 from Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
Authors: Kanerva Anna , Nokisalmi Petri , Diaconu Iulia , Koski Anniina , Cerullo Vincenzo , Liikanen Ilkka , Tähtinen Siri , Oksanen Minna , Heiskanen Raita , Pesonen Saila , Joensuu Timo , Alanko Tuomo , Partanen Kaarina , Laasonen Leena , Kairemo Kalevi , Pesonen Sari , Kangasniemi Lotta , Hemminki Akseli
Published: April 2023

PDF file - 67K, Adverse reactions in patients na�ve to oncolytic adenovirus.
Supplementary Figure 3 from Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
Authors: Kanerva Anna , Nokisalmi Petri , Diaconu Iulia , Koski Anniina , Cerullo Vincenzo , Liikanen Ilkka , Tähtinen Siri , Oksanen Minna , Heiskanen Raita , Pesonen Saila , Joensuu Timo , Alanko Tuomo , Partanen Kaarina , Laasonen Leena , Kairemo Kalevi , Pesonen Sari , Kangasniemi Lotta , Hemminki Akseli
Published: April 2023

PDF file - 889K, Individual anti-tumor (survivin) and anti-viral (Ad5) ELISPOT results in single (A) and serial (B) treated patients.
Supplementary Figure 1 from Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
Authors: Kanerva Anna , Nokisalmi Petri , Diaconu Iulia , Koski Anniina , Cerullo Vincenzo , Liikanen Ilkka , Tähtinen Siri , Oksanen Minna , Heiskanen Raita , Pesonen Saila , Joensuu Timo , Alanko Tuomo , Partanen Kaarina , Laasonen Leena , Kairemo Kalevi , Pesonen Sari , Kangasniemi Lotta , Hemminki Akseli
Published: April 2023

PDF file - 94K, The phenotypic panel of circulating white blood cells.
Supplemental Table 3 from Anticancer Effects of Niclosamide in Human Glioblastoma
Authors: Wieland Anja , Trageser Daniel , Gogolok Sabine , Reinartz Roman , Höfer Heike , Keller Mihaela , Leinhaas Anke , Schelle Ramona , Normann Sabine , Klaas Lil , Waha Andreas , Koch Philipp , Fimmers Rolf , Pietsch Torsten , Yachnis Anthony T. , Pincus David W. , Steindler Dennis A. , Brüstle Oliver , Simon Matthias , Glas Martin , Scheffler Björn
Published: April 2023

Killer plate® compounds and screening data.
Supplementary Figure 3 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity
Authors: Loo Deryk , Alderson Ralph F. , Chen Francine Z. , Huang Ling , Zhang Wenjun , Gorlatov Sergey , Burke Steve , Ciccarone Valentina , Li Hua , Yang Yinhua , Son Tom , Chen Yan , Easton Ann N. , Li Jonathan C. , Rillema Jill R. , Licea Monica , Fieger Claudia , Liang Tony W. , Mather Jennie P. , Koenig Scott , Stewart Stanford J. , Johnson Syd , Bonvini Ezio , Moore Paul A.
Published: April 2023

PDF file, 89KB, Measurement of IL-5 (Panel A), IL-6 (Panel B) and TNF-B (Panel C) cytokine levels in serum samples collected from cynomolgus monkeys prior to infusion (Pre) or at the indicated time points following intravenous administration of PBS vehicle (Day 1) or MGA271 at the indicated dose (Day 8). The top two panels of each cytokine data set represent all animals (N=6) in each dosing group, while the bottom three panels represent only the recovery group animals (N=2) in each dosing group. Sera from the samples were analyzed for cytokine levels using the Becton Dickinson Cytometric Bead Array Non-Human Primate Th1/Th2 Cytokine kit.
Supplementary Figure 1 from Spleen Cells from Young but Not Old Immunized Mice Eradicate Large Established Cancers
Authors: Schreiber Karin , Arina Ainhoa , Engels Boris , Spiotto Michael T. , Sidney John , Sette Alessandro , Karrison Theodore G. , Weichselbaum Ralph R. , Rowley Donald A. , Schreiber Hans
Published: April 2023

PDF file, 174KB, A cancer progressor variant is selected by a young mouse upon injection of cryopreserved 8101 original tumor fragments.
Supplementary Figure 2 from Proliferation in the Normal FTE Is a Hallmark of the Follicular Phase, Not BRCA Mutation Status
Authors: George Sophia H.L. , Milea Anca , Shaw Patricia A.
Published: April 2023

PDF file, 634K, Distribution of Ki67+ cells in histological normal FTE based on age. There was no statistical difference looking at ranges 45, 50 or 55 years of age as a cutoff for initiation of menopause.
Supplemental Material Section S6 from miRNA Landscape in Stage I Epithelial Ovarian Cancer Defines the Histotype Specificities
Authors: Calura Enrica , Fruscio Robert , Paracchini Lara , Bignotti Eliana , Ravaggi Antonella , Martini Paolo , Sales Gabriele , Beltrame Luca , Clivio Luca , Ceppi Lorenzo , Di Marino Mariacristina , Fuso Nerini Ilaria , Zanotti Laura , Cavalieri Duccio , Cattoretti Giorgio , Perego Patrizia , Milani Rodolfo , Katsaros Dionyssios , Tognon Germana , Sartori Enrico , Pecorelli Sergio , Mangioni Costantino , D'Incalci Maurizio , Romualdi Chiara , Marchini Sergio
Published: April 2023

PDF file - 217K, The clinical stratification of the 76 selected patients used for the integrative analysis and the MAGIA2 complete results.
Supplementary Figure 2 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

PDF file - 312K, Kaplan-Meier suvival plots of the Uppsala cohort for the top prognostic genes according to gene expression
Supplementary Figure 1 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

PDF file - 123K, Survival plot and Kaplan-Meier analysis of clinical parameters in the Uppsala cohort
Supplementary Table 2 from Characterization of Gene Amplification–Driven SKP2 Overexpression in Myxofibrosarcoma: Potential Implications in Tumor Progression and Therapeutics
Authors: Li Chien-Feng , Wang Ju-Ming , Kang Hong-Yo , Huang Chiung-Kuei , Wang Jun-Wen , Fang Fu-Min , Wang Yu-Hui , Wu Wen-Ren , Li Shau-Hsuan , Yu Shih-Chen , Lee Jen-Chieh , Lan Jui , Shiue Yow-Ling , Wu Li-Ching , Huang Hsuan-Ying
Published: April 2023

PDF file - 127K
Supplementary Table 1 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

XLS file 41K, RPPA biomarkers
Supplementary Figure 3 from Characterization of Gene Amplification–Driven SKP2 Overexpression in Myxofibrosarcoma: Potential Implications in Tumor Progression and Therapeutics
Authors: Li Chien-Feng , Wang Ju-Ming , Kang Hong-Yo , Huang Chiung-Kuei , Wang Jun-Wen , Fang Fu-Min , Wang Yu-Hui , Wu Wen-Ren , Li Shau-Hsuan , Yu Shih-Chen , Lee Jen-Chieh , Lan Jui , Shiue Yow-Ling , Wu Li-Ching , Huang Hsuan-Ying
Published: April 2023

PDF file - 102K, By using an ELISA-based, colorimetric assay to assess the rate of BrdU uptake, cell proliferation are significantly reduced in stable SKP2-knockdown OH931 (left) and NMFH-1 (right) cell lines compared to the corresponding controls transduced with shLacZ.
Supplementary Data from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

PDF file 117K, Supplementary Materials and Methods -Supplementary Figure Legends -Supplementary Table Legends
Supplementary Figure 1 from Phase I Trial of a Glypican-3–Derived Peptide Vaccine for Advanced Hepatocellular Carcinoma: Immunologic Evidence and Potential for Improving Overall Survival
Authors: Sawada Yu , Yoshikawa Toshiaki , Nobuoka Daisuke , Shirakawa Hirofumi , Kuronuma Toshimitsu , Motomura Yutaka , Mizuno Shoichi , Ishii Hiroshi , Nakachi Kohei , Konishi Masaru , Nakagohri Toshio , Takahashi Shinichiro , Gotohda Naoto , Takayama Tadatoshi , Yamao Kenji , Uesaka Katsuhiko , Furuse Junji , Kinoshita Taira , Nakatsura Tetsuya
Published: April 2023

PDF file, 60KB, Expression of GPC3 and HLA class I in cases 8 and 25 was determined by immunohistochemistry. Magnification = 200�.
Supplementary Video from A Novel Engineered Anti-CD20 Tracer Enables Early Time PET Imaging in a Humanized Transgenic Mouse Model of B-cell Non-Hodgkins Lymphoma
Authors: Natarajan Arutselvan , Hackel Benjamin J. , Gambhir Sanjiv Sam
Published: April 2023

MP4 file 847K, Movie of 64Cu-Do-FN3 PET tracer in a huCD20TM mouse. PET/CT images of two groups of huCD20TM 4 h post-injection of 64Cu-Do-FN3 tracer. (Left) Mouse received only tracer (non-blocked); (Right) Mouse (blocked) with pre-dose of cold FN3, 2 h prior to tracer. The 64Cu-Do-FN3 tracer uptake by spleen without block is very high compared to the blocked mouse
Supplementary Tables 1-3 from Frequent Inactivation of Cysteine Dioxygenase Type 1 Contributes to Survival of Breast Cancer Cells and Resistance to Anthracyclines
Authors: Jeschke Jana , O'Hagan Heather M. , Zhang Wei , Vatapalli Rajita , Calmon Marilia Freitas , Danilova Ludmila , Nelkenbrecher Claudia , Van Neste Leander , Bijsmans Ingrid T.G.W. , Van Engeland Manon , Gabrielson Edward , Schuebel Kornel E. , Winterpacht Andreas , Baylin Stephen B. , Herman James G. , Ahuja Nita
Published: April 2023

PDF File - 77K, Supplementary Table 1 displays baseline characteristics of normal breast donors and breast cancer patients.
Supplementary Figure 5 from Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma
Authors: Takahashi Yoko , Kupferman Michael E. , Bell Diana , Jiffar Tilahun , Lee June Goo , Xie Tong-Xin , Li Ning-Wei , Zhao Mei , Frederick Mitchell J. , Gelbard Alexander , Myers Jeffrey N. , Hanna Ehab Y.
Published: April 2023

PDF file - 169K, Tumorigenicity of MDA8788-7 cells. Tumorigenicity was examined by injecting cells into the flanks of the mice. (A) The cells injected into the flank without Matrigel formed in 75% of mice (6 of 8 mice). (B) By adding Matrigel, tumors grew much larger than the ones without adding Matrigel. (C) Average size of the tumors. (D) H& E staining from the tumor of the flank injection showed very similar appearance to the surgical specimen from the SNUC patient. The original magnifications x40 (left) and x200 (right).
Supplementary Figure 3 from Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma
Authors: Takahashi Yoko , Kupferman Michael E. , Bell Diana , Jiffar Tilahun , Lee June Goo , Xie Tong-Xin , Li Ning-Wei , Zhao Mei , Frederick Mitchell J. , Gelbard Alexander , Myers Jeffrey N. , Hanna Ehab Y.
Published: April 2023

PDF file - 90K, Expression pattern of epithelial-mesenchymal transition markers in early and late passage SNUC cells. Expression pattern of epithelial markers (pan-keratin and E-cadherin) and mesenchymal markers (α-SMA and vimentin) in both early (at passage number 17 in MDA8788-6 and at passage number 15 in MDA8788-7) and late passage (at passage number 40) in the SNUC cells was analyzed by Western blotting. Both early and late passage of SNUC cells expressed only the epithelial markers and did not expressed mesenchymal markers.
Supplementary Figure 6 from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 26K, Integrin β1 knock-down did not affected cell proliferation.
Supplementary Figure 4 from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 58K, Over expression of MMP-2 in M4E-15 integrin beta 1 knock-down cells increased the invasive capability.
Supplementary Tables 1 - 2 from Validation of a Radiosensitivity Molecular Signature in Breast Cancer
Authors: Eschrich Steven A. , Fulp William J. , Pawitan Yudi , Foekens John A. , Smid Marcel , Martens John W.M. , Echevarria Michelle , Kamath Vidya , Lee Ji-Hyun , Harris Eleanor E. , Bergh Jonas , Torres-Roca Javier F.
Published: April 2023

PDF file, 81K, Online Table 1. Clinical Characteristics of Patients in Both Datasets. Online Table 2. Distribution of Recurrences by Group (Karolinka Dataset).
Supplementary Tables 1 - 4 from Chromosome 5q Loss in Colorectal Flat Adenomas
Authors: Voorham Quirinus J.M. , Carvalho Beatriz , Spiertz Angela J. , van Grieken Nicole C.T. , Mongera Sandra , Rondagh Eveline J.A. , van de Wiel Mark A. , Jordanova Ekaterina S. , Ylstra Bauke , Kliment Martin , Grabsch Heike , Rembacken Bjorn J. , Arai Tomio , de Bruïne Adriaan P. , Sanduleanu Silvia , Quirke Philip , Mulder Chris J.J. , van Engeland Manon , Meijer Gerrit A.
Published: April 2023

PDF file, 100K, Supplementary table 1; Common chromosomal regions present in more than 10% of polypoid or flat colorectal adenomas. Supplementary table 2; All known genes and microRNA located on 5q15-q31.1 Supplementary table 3; Cross tables of A; APC mutation status versus phenotype, B; APC mutation status versus presents of 5qloss in flat adenomas, C; APC mutation status versus presents of 5q loss in polypoid adenomas, D; The amount of beta-catenin binding repeats versus phenotype. Supplementary table 4; Significant different chromosomal regions (FDR<0.2) in adenomas for subtype, dysplasia and origin; FDR, false discovery rate; Bold, more than 20% in one of the lesion types.
Supplementary Table S1 from Prospective Phase II Study on 5-Days Azacitidine for Treatment of Symptomatic and/or Erythropoietin Unresponsive Patients with Low/INT-1–Risk Myelodysplastic Syndromes
Authors: Filì Carla , Malagola Michele , Follo Matilde Y. , Finelli Carlo , Iacobucci Ilaria , Martinelli Giovanni , Cattina Federica , Clissa Cristina , Candoni Anna , Fanin Renato , Gobbi Marco , Bocchia Monica , Defina Marzia , Spedini Pierangelo , Skert Cristina , Manzoli Lucia , Cocco Lucio , Russo Domenico
Published: April 2023

Supplementary Table S1 - PDF file 69K, Summary of macroscopic CNAs and LOH alterations identified in MDS patients and response to fourth cycle of 5d-Aza. The table summarizes the results of SNP karyotyping, LOH and CNAs in the 26 MDS patients for whom the an
Supplementary Materials and Methods from Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
Authors: Hakimi A. Ari , Ostrovnaya Irina , Reva Boris , Schultz Nikolaus , Chen Ying-Bei , Gonen Mithat , Liu Han , Takeda Shugaku , Voss Martin H. , Tickoo Satish K. , Reuter Victor E. , Russo Paul , Cheng Emily H. , Sander Chris , Motzer Robert J. , Hsieh James J.
Published: April 2023

PDF File - 70K, Supplemental Methods.
Supplementary Table 1, Figures 1 - 3 from Development, Characterization, and Reversal of Acquired Resistance to the MEK1 Inhibitor Selumetinib (AZD6244) in an In Vivo Model of Childhood Astrocytoma
Authors: Bid Hemant K. , Kibler Aaron , Phelps Doris A. , Manap Sagymbek , Xiao Linlin , Lin Jiayuh , Capper David , Oswald Duane , Geier Brian , DeWire Mariko , Smith Paul D. , Kurmasheva Raushan T. , Mo Xiaokui , Fernandez Soledad , Houghton Peter J.
Published: April 2023

PDF file - 9027K, Supplemental Table 1 and supplemental Figures 1-3 Supplemental Table 1. MEK functional activation gene signature qRT-PCR results Supplemental Figure 1. For individual growth curve plots: Upper left panel: Control; Upper right panel: AZD6244 100 mg/kg BID x 5/SID x 2 for six consecutive weeks; lower left panel: AZD6244 75 mg/kg BID x 5/SID x 2 for six consecutive weeks; Lower right panel100 mg/kg SID for six consecutive weeks. Tumors A5 and B4 (arrowed) were selected for further transplant to select for selumetinib resistance in vivo. Supplemental Figure 2. Representative immunostaining of BT-40 and derivative xenografts using the VE1 antibody that recognizes BRAFV600E.Tumor samples were fixed and stained as described in a Materials and Methods and read 'blinded' (DC). Panels at the bottom were stained simultaneously and demonstrate intensity of staining for patient derived brain tumors. Supplemental Figure 3. qRT-�PCR to detect IL6 receptor alpha was performed using human-specific primers on snap-�frozen control tumor tissue as described in Supplemental Table 1.
Supplementary Figure 5 from Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ- and GNA11-Dependent Manner
Authors: Khalili Jahan S. , Yu Xiaoxing , Wang Ji , Hayes Brendan C. , Davies Michael A. , Lizee Gregory , Esmaeli Bita , Woodman Scott E.
Published: April 2023

PDF file, 30K, Effect of MEKi and/or PI3Ki treatment on p-cjun protein expression.
Supplementary Table S21 from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Table S21: Table S21. Drug sensitivity and TP53 mutational status data on squamous cell carcinoma cell lines from COSMIC on Wee1/Chk1 Inhibitor (681460)
Supplementary Figure S4 from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Figure S4. Body weight of MK-1775 treated mice
Supplementary Figure S3 from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Figure S3. Correlation plots of autologous HNSCC cell line pairs utilizing kinomic profile
Supplementary Methods from BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition
Authors: Hutchinson Katherine E. , Lipson Doron , Stephens Philip J. , Otto Geoff , Lehmann Brian D. , Lyle Pamela L. , Vnencak-Jones Cindy L. , Ross Jeffrey S. , Pietenpol Jennifer A. , Sosman Jeffrey A. , Puzanov Igor , Miller Vincent A. , Pao William
Published: April 2023

PDF file - 104K, Supplementary Materials and Methods. Case histories of patients with BRAF fusions; FoundationOneTM and RNA sequencing assays and data analysis; cloning, transfections, drug treatment, and immunoblotting procedures; BRAF fusion detection and reverse phase protein array (RPPA) analysis from TCGA data.
Supplementary Table 2 from Expression of Interleukin-4 Receptor Alpha in Human Pleural Mesothelioma Is Associated with Poor Survival and Promotion of Tumor Inflammation
Authors: Burt Bryan M. , Bader Andrew , Winter Daniel , Rodig Scott J. , Bueno Raphael , Sugarbaker David J.
Published: April 2023

PDF file - 49K
Supplementary Figure Legends 1-2 from Expression of Interleukin-4 Receptor Alpha in Human Pleural Mesothelioma Is Associated with Poor Survival and Promotion of Tumor Inflammation
Authors: Burt Bryan M. , Bader Andrew , Winter Daniel , Rodig Scott J. , Bueno Raphael , Sugarbaker David J.
Published: April 2023

PDF file - 52K
Supplementary Methods and Figure Legend from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer
Authors: Marchini Sergio , Poynor Elizabeth , Barakat Richard R. , Clivio Luca , Cinquini Michela , Fruscio Robert , Porcu Luca , Bussani Cecilia , D’Incalci Maurizio , Erba Eugenio , Romano Michela , Cattoretti Giorgio , Katsaros Dionyssios , Koff Andrew , Luzzatto Lucio
Published: April 2023

PDF file, 113K.
Supplementary Figure 2 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer
Authors: Marchini Sergio , Poynor Elizabeth , Barakat Richard R. , Clivio Luca , Cinquini Michela , Fruscio Robert , Porcu Luca , Bussani Cecilia , D’Incalci Maurizio , Erba Eugenio , Romano Michela , Cattoretti Giorgio , Katsaros Dionyssios , Koff Andrew , Luzzatto Lucio
Published: April 2023

PDF file, 96K, Role in transformation of individual domains of ZIC2 protein assessed by deletion analysis.
Supplementary Figure 3 from FoxM1 Inhibition Sensitizes Resistant Glioblastoma Cells to Temozolomide by Downregulating the Expression of DNA-Repair Gene Rad51
Authors: Zhang Nu , Wu Xinjian , Yang Lixuan , Xiao Feizhe , Zhang Heng , Zhou Aidong , Huang Zhengsong , Huang Suyun
Published: April 2023

PDF file - 79K, Supplementary Fig.3. Flow cytometry assay shows the percentage of cells arrested in G2 stage after treatment by TMZ in U87 and two recurrent GBM cell lines
Supplementary Figure 2 from Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice
Authors: Fan Haitao , Zhang Ian , Chen Xuebo , Zhang Leying , Wang Huaqing , Da Fonseca Anna , Manuel Edwin R. , Diamond Don J. , Raubitschek Andrew , Badie Behnam
Published: April 2023

PDF file, 197K, Antitumor activity of intracranial CNT-CpG.
Related Article from Dual PI3K/mTOR Inhibitors: Does p53 Modulate Response?
Authors: Ekshyyan Oleksandr , Anandharaj Arunkumar , Nathan Cherie-Ann O.
Published: April 2023

Related Article from Dual PI3K/mTOR Inhibitors: Does p53 Modulate Response?
Supplementary Table 3 from Transcriptional Characterization of a Prospective Series of Primary Plasma Cell Leukemia Revealed Signatures Associated with Tumor Progression and Poorer Outcome
Authors: Todoerti Katia , Agnelli Luca , Fabris Sonia , Lionetti Marta , Tuana Giacomo , Mosca Laura , Lombardi Luigia , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Morabito Fortunato , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Omede' Paola , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino , Musto Pellegrino
Published: April 2023

PDF file - 114K, Table of the most significant gene sets in GSEA analysis of pPCL versus MM, ordered according to adjusted false discovery rate.
Data Supplement from Functional p38 MAPK Identified by Biomarker Profiling of Pancreatic Cancer Restrains Growth through JNK Inhibition and Correlates with Improved Survival
Authors: Zhong Yi , Naito Yoshiki , Cope Leslie , Naranjo-Suarez Salvador , Saunders Tyler , Hong Seung-Mo , Goggins Michael G. , Herman Joseph M. , Wolfgang Christopher L. , Iacobuzio-Donahue Christine A.
Published: April 2023

Supplemental Figure Legends
Data Supplement from Functional p38 MAPK Identified by Biomarker Profiling of Pancreatic Cancer Restrains Growth through JNK Inhibition and Correlates with Improved Survival
Authors: Zhong Yi , Naito Yoshiki , Cope Leslie , Naranjo-Suarez Salvador , Saunders Tyler , Hong Seung-Mo , Goggins Michael G. , Herman Joseph M. , Wolfgang Christopher L. , Iacobuzio-Donahue Christine A.
Published: April 2023

Supplemental Table 1. Discovery Set of 36 Patients. Supplemental Table 2. Antibodies. Supplemental Table 3. Validation Set of 83 Patients. Supplemental Table 4. Univariate Analyses of pp38 Expression.
Supplementary Figure 5 from hVps37A Status Affects Prognosis and Cetuximab Sensitivity in Ovarian Cancer
Authors: Wittinger Michael , Vanhara Petr , El-Gazzar Ahmed , Savarese-Brenner Bettina , Pils Dietmar , Anees Mariam , Grunt Thomas W. , Sibilia Maria , Holcmann Martin , Horvat Reinhard , Schemper Michael , Zeillinger Robert , Schöfer Christian , Dolznig Helmut , Horak Peter , Krainer Michael
Published: April 2023

PDF file - 186K
Supplementary Table 5 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 104K, Association of the PAM50 Proliferation, RORS and RORP continuous scores with response and event-free survival (EFS).
Supplementary Table 3 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 92K, Affymetrix U133A 2.0 probes used for in this study for PAM50 subtyping.
Supplementary Figure 1 from Regulation of Colorectal Carcinoma Stemness, Growth, and Metastasis by an miR-200c-Sox2–Negative Feedback Loop Mechanism
Authors: Lu Yan-Xia , Yuan Li , Xue Xiao-Lei , Zhou Min , Liu Yan , Zhang Chao , Li Jing-Ping , Zheng Lin , Hong Min , Li Xue-Nong
Published: April 2023

PDF file - 322KB, Showed that we have constructed SW480/miR-200c, SW620/miR-200c, SW480/miR-200c/Sox2, SW620/miR-200c/Sox2,SW480/zip-200c and HCT116/zip-200c sub-cell lines.The expression of miR-200c Sox2 was tested.
Supplementary Tables 1 - 8 from FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
Authors: Cui Jiujie , Shi Min , Xie Dacheng , Wei Daoyan , Jia Zhiliang , Zheng Shaojiang , Gao Yong , Huang Suyun , Xie Keping
Published: April 2023

PDF file - 176KB, Supplementary Table S1. PCR primers for the enzymes in the glycolytic pathway. Supplementary Table S2. Clinicopathologic characteristics of the patients represented in TMA. Supplementary Table S3. Clinicopathologic characteristics of the patients represented in TMA-P. Supplementary Table S4. Matching of clinicopathologic characteristics of the patients represented in TMA and TMA-P. Supplementary Table S5. FOXM1 expression in and clinicopathologic characteristics of the patients represented in TMA. Supplementary Table S6. LDHA expression in and clinicopathologic characteristics of the patients represented in TMA. Supplementary Table S7. FOXM1 expression in and clinicopathologic characteristics of the patients represented in TMA-P. Supplementary Table S8. LDHA expression in and clinicopathologic characteristics of the patients represented in TMA-P.
Supplementary Figure Legend from Colonization of the Human Gut by E. coli and Colorectal Cancer Risk
Authors: Bonnet Mathilde , Buc Emmanuel , Sauvanet Pierre , Darcha Claude , Dubois Damien , Pereira Bruno , Déchelotte Pierre , Bonnet Richard , Pezet Denis , Darfeuille-Michaud Arlette
Published: April 2023

PDF file - 20K
Supplementary Figure 1 from Quantitative Measurements of Tumoral p95HER2 Protein Expression in Metastatic Breast Cancer Patients Treated with Trastuzumab: Independent Validation of the p95HER2 Clinical Cutoff
Authors: Duchnowska Renata , Sperinde Jeff , Chenna Ahmed , Haddad Mojgan , Paquet Agnes , Lie Yolanda , Weidler Jodi M. , Huang Weidong , Winslow John , Jankowski Tomasz , Czartoryska-Arłukowicz Bogumiła , Wysocki Piotr J. , Foszczyńska-Kłoda Małgorzata , Radecka Barbara , Litwiniuk Maria M. , Żok Jolanta , Wiśniewski Michał , Zuziak Dorota , Biernat Wojciech , Jassem Jacek
Published: April 2023

PDF file - 474KB, Supplemental Figure S1. Expanded p95 IHC images from Figure 4A.
Supplement Figure 3 from Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study
Authors: Wang Jiping , Carvajal-Carmona Luis G. , Chu Jen-Hwa , Zauber Ann G. , Kubo Michikai , Matsuda Koichi , Dunlop Malcolm , Houlston Richard S. , Sieber Oliver , Lipton Lara , Gibbs Peter , Martin Nicholas G. , Montgomery Grant W. , Young Joanne , Baird Paul N. , Ratain Mark J. , Nakamura Yusuke , Weiss Scott T. , Tomlinson Ian , Bertagnolli Monica M.
Published: April 2023

Supplement Figure 3
Supplementary Figure Legend from Serial Diffusion MRI to Monitor and Model Treatment Response of the Targeted Nanotherapy CRLX101
Authors: Ng Thomas S.C. , Wert David , Sohi Hargun , Procissi Daniel , Colcher David , Raubitschek Andrew A. , Jacobs Russell E.
Published: April 2023

PDF file - 62K
Supplementary Figure 2 from Serial Diffusion MRI to Monitor and Model Treatment Response of the Targeted Nanotherapy CRLX101
Authors: Ng Thomas S.C. , Wert David , Sohi Hargun , Procissi Daniel , Colcher David , Raubitschek Andrew A. , Jacobs Russell E.
Published: April 2023

PDF file - 112K, Quantitative histological assessment of CRLX101 and CPT-11 response. Tumors treated with CRLX101 (5 mg/kg), CPT-11 (100 mg/kg) or saline were harvested for histology on days 0, 2, 4, and 7. Tumor samples were subsequently sectioned and stained with (A) Cleaved caspase-3 (co-stained with hematoxylin), (B) TUNEL (co-stained with hematoxylin), (C) Ki-67 (co-stained with hematoxylin) and (D) H&E. Three fields of view from each tumor slide were analyzed to obtain measurements of positive cleaved caspase-3 and TUNEL staining, percentage of Ki-67 expression and cellular density (as demonstrated by hematoxylin staining). Statistically significant values, as compared to the control cohort for each time point, are highlighted (p < 0.01, *, p < 0.05, �). Error bars denote standard error.
Supplementary Figure 3 from Activity of the Hypoxia-Activated Prodrug, TH-302, in Preclinical Human Acute Myeloid Leukemia Models
Authors: Portwood Scott , Lal Deepika , Hsu Yung-Chun , Vargas Rodrigo , Johnson Megan K. , Wetzler Meir , Hart Charles P. , Wang Eunice S.
Published: April 2023

PDF file - 98K, Supplemental Figure 3. Cytarabine induces apoptosis of human AML (HL60/PAR) cells in a dose and time-dependent manner.
Supplementary Figure 1 from Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer
Authors: Cañadas Israel , Rojo Federico , Taus Álvaro , Arpí Oriol , Arumí-Uría Montserrat , Pijuan Lara , Menéndez Silvia , Zazo Sandra , Dómine Manuel , Salido Marta , Mojal Sergi , García de Herreros Antonio , Rovira Ana , Albanell Joan , Arriola Edurne
Published: April 2023

PDF file - 441K, Cellular and molecular changes induced by Met inhibitors.
Supplementary Tables from Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008
Authors: Burvenich Ingrid J.G. , Lee Fook T. , Cartwright Glenn A. , O'Keefe Graeme J. , Makris Dahna , Cao Diana , Gong Sylvia , Chueh Anderly C. , Mariadason John M. , Brechbiel Martin W. , Beckman Robert A. , Fujiwara Kosaku , von Roemeling Reinhard , Scott Andrew M.
Published: April 2023

Supplementary Tables - PDF file 68K, supplementary tables
Supplementary Data from Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008
Authors: Burvenich Ingrid J.G. , Lee Fook T. , Cartwright Glenn A. , O'Keefe Graeme J. , Makris Dahna , Cao Diana , Gong Sylvia , Chueh Anderly C. , Mariadason John M. , Brechbiel Martin W. , Beckman Robert A. , Fujiwara Kosaku , von Roemeling Reinhard , Scott Andrew M.
Published: April 2023

Supplementary Data - PDF file 92K, Supplementary Data
Supplementary Figures from PIK3CA and AKT1 Mutations Have Distinct Effects on Sensitivity to Targeted Pathway Inhibitors in an Isogenic Luminal Breast Cancer Model System
Authors: Beaver Julia A. , Gustin John P. , Yi Kyung H. , Rajpurohit Anandita , Thomas Matthew , Gilbert Samuel F. , Rosen D. Marc , Ho Park Ben , Lauring Josh
Published: April 2023

PDF file, 526K, Supplementary Figure 1. Genomic DNA and cDNA sequencing verification of additional gene-targeted MCF-7 derivatives. Supplementary Figure 2. PI3K pathway signaling in low serum conditions. Supplementary Figure 3. Estrogenic stimulation of growth. Supplementary Figure 4. GDC-0941 and MK-2206 treatment of MCF-7 cells and three gene-targeted derivatives with a single mutant copy of PIK3CA (Het 1-3). Supplementary Figure 5. MK-2206 treatment of isogenic MCF-10A cells. Supplementary Figure 6. Perifosine treatment of MCF-7 and cells with wild type PIK3CA and AKT1, mutant PIK3CA, or mutant AKT1 genes.
Supplementary Tables from Tumor Imaging and Interferon-γ–Inducible Protein-10 Gene Transfer Using a Highly Efficient Transferrin-Conjugated Liposome System in Mice
Authors: Zhuo Huiqin , Peng Yi , Yao Qin , Zhou Nuo , Zhou Sufang , He Jian , Fang Yuan , Li Xi , Jin Hongwei , Lu Xiaoling , Zhao Yongxiang
Published: April 2023

Supplementary Tables - PDF file 87K, Table S1. Physical properties of liposomes Top: Concentrations of ethanol and Ca2+ for optimized liposome preparation. Bottom: Diameters and surface potentials of P-Ls entrapped pcDNA3.1-IP-10 and PTf-Ls entrapped pcDNA3.1-IP-10 prepared by Method III; Table S2. Chemical composition of liposome surfaces from XPS analysis; Table S3. Serum stability of PTf-Ls entrapped pcDNA3.1-IP-10
Supplementary Figure 1 from Comparison of Statistical Analysis Plans in Randomize-All Phase III Trials with a Predictive Biomarker
Authors: Matsui Shigeyuki , Choai Yuki , Nonaka Takahiro
Published: April 2023

PDF file - 62KB, P overall, P subset, and P success, for various numbers of events, E, under constant effects (HR+, HR−) = (0.7, 0.7).
Supplementary Tables from A Collagen-Remodeling Gene Signature Regulated by TGF-β Signaling Is Associated with Metastasis and Poor Survival in Serous Ovarian Cancer
Authors: Cheon Dong-Joo , Tong Yunguang , Sim Myung-Shin , Dering Judy , Berel Dror , Cui Xiaojiang , Lester Jenny , Beach Jessica A. , Tighiouart Mourad , Walts Ann E. , Karlan Beth Y. , Orsulic Sandra
Published: April 2023

XLS file 139K, Supplementary Tables. Supplementary Table 1A-C. Poor prognosis genes identified from 3 different datasets (A) TCGA, (B) GSE26712, (C) Karlan. Supplementary Table 2. Functional annotation of poor prognosis genes in three datasets. Supplementary Table 3. PCR primer sequences. Supplementary Table 4. Genes and corresponding probes used for Oncomine analysis of expression in primary tumors and metastases. Supplementary Table 5.Matched primary, metastatic and recurrent tumor samples -
Supplementary Figure Legend from Ketogenic Diets Enhance Oxidative Stress and Radio-Chemo-Therapy Responses in Lung Cancer Xenografts
Authors: Allen Bryan G. , Bhatia Sudershan K. , Buatti John M. , Brandt Kristin E. , Lindholm Kaleigh E. , Button Anna M. , Szweda Luke I. , Smith Brian J. , Spitz Douglas R. , Fath Melissa A.
Published: April 2023

Supplementary Figure Legend - PDF file 71K, Supplementary Figure Legend
Supplementary Table S1 from Overexpression of the Circadian Clock Gene Bmal1 Increases Sensitivity to Oxaliplatin in Colorectal Cancer
Authors: Zeng Zhao-lei , Luo Hui-yan , Yang Jing , Wu Wen-jing , Chen Dong-liang , Huang Peng , Xu Rui-hua
Published: April 2023

PDF file 59K, Clinicopathological characteristics of patient samples and expression of Bmal1 in colorectal cancer
Supplementary Table 1 from Rb Loss Is Characteristic of Prostatic Small Cell Neuroendocrine Carcinoma
Authors: Tan Hsueh-Li , Sood Akshay , Rahimi Hameed A. , Wang Wenle , Gupta Nilesh , Hicks Jessica , Mosier Stacy , Gocke Christopher D. , Epstein Jonathan I. , Netto George J. , Liu Wennuan , Isaacs William B. , De Marzo Angelo M. , Lotan Tamara L.
Published: April 2023

PDF file - 82K, Supplementary Table 1: RB1 status (from high density SNP microarray, Reference 30) and Rb protein status across castrate resistant prostate cancer metastases. n = negative, p = positive, LOH = loss of heterozygosity.
Supplementary Table 4 from Lack of Estrogen Receptor-α Is Associated with Epithelial–Mesenchymal Transition and PI3K Alterations in Endometrial Carcinoma
Authors: Wik Elisabeth , Ræder Maria B. , Krakstad Camilla , Trovik Jone , Birkeland Even , Hoivik Erling A. , Mjos Siv , Werner Henrica M.J. , Mannelqvist Monica , Stefansson Ingunn M. , Oyan Anne M. , Kalland Karl H. , Akslen Lars A. , Salvesen Helga B.
Published: April 2023

PDF file - 68 KB, Subset of endometrioid cases, retrospective population based series. Cox' proportional hazard regression model used to estimate the prognostic value of ER� in relation to traditional prognostic markers in endometrial carcinoma.
Supplementary Figure 6 from TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance
Authors: Silwal-Pandit Laxmi , Vollan Hans Kristian Moen , Chin Suet-Feung , Rueda Oscar M. , McKinney Steven , Osako Tomo , Quigley David A. , Kristensen Vessela N. , Aparicio Samuel , Børresen-Dale Anne-Lise , Caldas Carlos , Langerød Anita
Published: April 2023

PDF file - 29KB, Figure S6. Kaplan-Meier survival curves. A. OS of TP53 mutation status in whole cohort B. BCSS of TP53 mutation status in patients not treated with adjuvant chemotherapy. Numbers at risk are listed below each chart e = no. of all deaths (OS) or Breast Cancer specific deaths (BCSS).
Supplementary Figure 1 from Lack of Estrogen Receptor-α Is Associated with Epithelial–Mesenchymal Transition and PI3K Alterations in Endometrial Carcinoma
Authors: Wik Elisabeth , Ræder Maria B. , Krakstad Camilla , Trovik Jone , Birkeland Even , Hoivik Erling A. , Mjos Siv , Werner Henrica M.J. , Mannelqvist Monica , Stefansson Ingunn M. , Oyan Anne M. , Kalland Karl H. , Akslen Lars A. , Salvesen Helga B.
Published: April 2023

PDF file - 138 KB, Study overview
Supplementary Figures 1-7 from A Pharmacokinetic/Pharmacodynamic Model of Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia Patients Treated with Flavopiridol
Authors: Ji Jia , Mould Diane R. , Blum Kristie A. , Ruppert Amy S. , Poi Ming , Zhao Yuan , Johnson Amy J. , Byrd John C. , Grever Michael R. , Phelps Mitch A.
Published: April 2023

PDF file - 255 KB, Figure 1. Flavopiridol conditional weighted residuals vs. time with a smoothed loess line. Figure 2. Flavopiridol conditional weighted residuals vs. population predicted values with a smoothed loess line. Figure 3. Visual predictive check (VPC) plots for flavopiridol stratified by body weight. Open circles, observed data; grey solid line, median of observed data at nominal time; grey dashed line, 95% confidence interval (CI) of observed data at nominal time; black solid line, median of simulated data at nominal time; black dashed line, 95% prediction interval (PI) of simulated data at nominal time; grey area, 95% CI around median or 95% PI of simulated time. Figure 4. Flavopiridol-glucuronide (Flavo-G) conditional weighted residuals vs. time with a smoothed loess line. Figure 5. Flavopiridol-glucuronide (Flavo-G) conditional weighted residuals vs. population predicted values with a smoothed loess line. Figure 6. Predicted median TLS probability vs. observed TLS probability with a line of unity. Figure 7. TLS probability vs. median parent drug (flavopiridol) AUC.
Supplemental Figure 2 from Complement Activation and Intraventricular Rituximab Distribution in Recurrent Central Nervous System Lymphoma
Authors: Kadoch Cigall , Li Jing , Wong Valerie S. , Chen Lingjing , Cha Soonmee , Munster Pamela , Lowell Clifford A. , Shuman Marc A. , Rubenstein James L.
Published: April 2023

Supplemental Figure 2. Effect of hypothetical brain tissue volume (V3) on rituximab disposition in CSF, serum and brain tissue after intraventricular administration. Figure 2A. V3 = 0 ml. Figure 2B. V3 = 320 ml. Figure 2C. V3 = 5000 ml.
Supplementary Figures and Tables from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth
Authors: Yepuru Muralimohan , Wu Zhongzhi , Kulkarni Anand , Yin Feng , Barrett Christina M. , Kim Juhyun , Steiner Mitchell S. , Miller Duane D. , Dalton James T. , Narayanan Ramesh
Published: April 2023

Supplementary Figures and Tables - PDF file 898K, Supplementary Table ST1: AKR1C3 over-expression in HEK-293 cells reduces IC50 of androgens. Supplementary Table ST2: Finasteride increases the testosterone formation. Supplementary Figure S1: Over-expression of AKR1C3 increases LNCaP xenograft growth in intact mice. Supplementary Figure S2: AR target FKBP51, but not AR, protein expression is increased in LNCaP-AKR1C3 xenograft tumors. Supplementary Figure S3: AKR1C3 translocation to nucleus requires AR. Top panel. NIH3T3-AKR1C3 cells infected with adenovirus LacZ. Bottom panel. NIH3T3-AKR1C3 cells infected with adenovirus AR.Supplementary Figure S4: AKR1C3 migrates with AR. Supplementary Figure S5: Duolink assay demonstrates interaction between AR and AKR1C3 in LNCaP-AKR1C3 cells. Supplementary Figure S6: AKR1C3 synergizes with SRC-2 in AR transactivation assay. Supplementary Figure S7: AKR1C3 dependent- androgen induced- AR transactivation is not cell type dependent. Transient transactivation studies conducted in COS-1 cells Supplementary Figure S8: AKR1C3-dependent increase in transactivation is selective to AR. Supplementary Figure S9: R1881 induced- AKR1C3 dependent- AR transactivation is not observed with other AKR1C. Supplementary Figure-S10: Different domains mediate the enzymatic and activator functions of AKR1C3. Supplementary Figure S11: GTx-560 is specific for AKR1C3. Supplementary Figure S12: HEK-293-AKR1C3 enzyme activity. Supplementary Figure S14: GTx-560 inhibits AKR1C3-dependent A�dione-induced AR transactivation at all concentration of AKR1C3. Supplementary Figure S15: Expression of steroidogenic enzymes in VCaP cells
Supplementary Table 6 from Identification of Campath-1 (CD52) as Novel Drug Target in Neoplastic Stem Cells in 5q-Patients with MDS and AML
Authors: Blatt Katharina , Herrmann Harald , Hoermann Gregor , Willmann Michael , Cerny-Reiterer Sabine , Sadovnik Irina , Herndlhofer Susanne , Streubel Berthold , Rabitsch Werner , Sperr Wolfgang R. , Mayerhofer Matthias , Rülicke Thomas , Valent Peter
Published: April 2023

PDF file - 83K, Supplementary Table S6: Expression of CD52, CD123 and CLL-1 on CD34+/CD38−/CD90+/CD45RA− cells in patients with MDS and on CD34+/CD38−/CD90−/CD45RA− cells in patients with AML.
Figure S1 Legend from HLA and Killer Immunoglobulin-like Receptor Genes as Outcome Predictors of Hepatitis C Virus–Related Hepatocellular Carcinoma
Authors: Cariani Elisabetta , Pilli Massimo , Zerbini Alessandro , Rota Cristina , Olivani Andrea , Zanelli Paola , Zanetti Adele , Trenti Tommaso , Ferrari Carlo , Missale Gabriele
Published: April 2023

Figure S1 Legend - PDF file 6K, Kir genotype distribution
Supplementary Information from Downregulation of miR-138 Sustains NF-κB Activation and Promotes Lipid Raft Formation in Esophageal Squamous Cell Carcinoma
Authors: Gong Hui , Song Libing , Lin Chuyong , Liu Aibin , Lin Xi , Wu Jueheng , Li Mengfeng , Li Jun
Published: April 2023

PDF file - 173 KB, Supplementary Materials and Methods, Supplementary Figure Legends, and Supplementary References
Supplementary Table 1 from CD62L as a Therapeutic Target in Chronic Lymphocytic Leukemia
Authors: Burgess Melinda , Gill Devinder , Singhania Richa , Cheung Catherine , Chambers Lynne , Renyolds Brent A. , Smith Louise , Mollee Peter , Saunders Nicholas , McMillan Nigel AJ
Published: April 2023

Supplementary Table 1 - PDF files 69K, Patient Data
Supplementary Figure Legends, Tables 1 - 3 from CTLA4 Blockade Broadens the Peripheral T-Cell Receptor Repertoire
Authors: Robert Lidia , Tsoi Jennifer , Wang Xiaoyan , Emerson Ryan , Homet Blanca , Chodon Thinle , Mok Stephen , Huang Rong Rong , Cochran Alistair J. , Comin-Anduix Begoña , Koya Richard C. , Graeber Thomas G. , Robins Harlan , Ribas Antoni
Published: April 2023

PDF file - 65KB, Table S1 Summary for TCR V-beta CDR3 sequence analysis. Table S2 Number of unique Productive Sequences in Top 25% abundance at four different timepoints. Table S3 Number of unique productive Sequences in Top 25% clones at baseline and at Day 30-60.
Supplementary Table 2 from The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low Xist Expression
Authors: Salvador Marion A. , Wicinski Julien , Cabaud Olivier , Toiron Yves , Finetti Pascal , Josselin Emmanuelle , Lelièvre Hélène , Kraus-Berthier Laurence , Depil Stéphane , Bertucci François , Collette Yves , Birnbaum Daniel , Charafe-Jauffret Emmanuelle , Ginestier Christophe
Published: April 2023

PDF file 43K, Phenotype of BCLs after abexinostat treatment
Supplementary Figure Legends from Lung Cancers with Concomitant EGFR Mutations and ALK Rearrangements: Diverse Responses to EGFR-TKI and Crizotinib in Relation to Diverse Receptors Phosphorylation
Authors: Yang Jin-Ji , Zhang Xu-Chao , Su Jian , Xu Chong-Rui , Zhou Qing , Tian Hong-Xia , Xie Zhi , Chen Hua-Jun , Huang Yi-Sheng , Jiang Ben-Yuan , Wang Zhen , Wang Bin-Chao , Yang Xue-Ning , Zhong Wen-Zhao , Nie Qiang , Liao Ri-Qiang , Mok Tony S. , Wu Yi-Long
Published: April 2023

PDF file - 63KB.
Supplementary Figure Legend from The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low Xist Expression
Authors: Salvador Marion A. , Wicinski Julien , Cabaud Olivier , Toiron Yves , Finetti Pascal , Josselin Emmanuelle , Lelièvre Hélène , Kraus-Berthier Laurence , Depil Stéphane , Bertucci François , Collette Yves , Birnbaum Daniel , Charafe-Jauffret Emmanuelle , Ginestier Christophe
Published: April 2023

PDF file 86K, supplementary figure legend
Supplementary Figure 5 from The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low Xist Expression
Authors: Salvador Marion A. , Wicinski Julien , Cabaud Olivier , Toiron Yves , Finetti Pascal , Josselin Emmanuelle , Lelièvre Hélène , Kraus-Berthier Laurence , Depil Stéphane , Bertucci François , Collette Yves , Birnbaum Daniel , Charafe-Jauffret Emmanuelle , Ginestier Christophe
Published: April 2023

PDF file 164K, Cell cycle progression was differentially altered by abexinostat according to drug-response profile