bluuebunny/crossref_metadata_2025 huggingface dataset:
STATE REGULATION OF ARCHIVAL STORAGE OF ELECTRONIC DOCUMENTS
Authors: Konobevcev F.
Published: September 2024

The practice of using electronic document management in Russia, an electronic document and its storage of the document in an electronic archive is considered. The current state of electronic signature and ways of its development are presented. An assessment is made of the state project for the mutual recognition of qualified electronic signatures in cross-border transactions. Aspects of the use of electronic document management systems and electronic archive systems are revealed, taking into account their institutionalization, the stages of the formation of electronic signatures and electronic document management are formalized. The current requirements of Russian legislation regarding the regulation of electronic archives are considered. The practice of applying Order 77 of the Federal Archive, which covered not only the sphere of public administration, but also the sphere of commercial organizations, is analyzed. As an example of automation of archival storage of electronic documents, the Russian information system 1C:Archive is considered.
The Effect of ZnCl2 Concentrations and Heating Methods on the Chlorophyll, Phenolic, Andrographolide Content and Antioxidant Activity of Sambiloto (Andrographis paniculata) Simplicia Powder
Authors: Suryani Chatarina Lilis , Suwarta FX , Fitri Ichlasia Ainul
Published: September 2024

The drying process in Sambiloto simplicia production causes the degradation of chlorophyll as the major compound. However, the stability of chlorophyll can be enhanced by forming a metallochlorophyll complex with zinc (Zn) metal. This research aims to produce Zn-rich Sambiloto simplicia powder to produce high stability of chlorophyll. Sambiloto simplicia powder was prepared through sorting, grinding, sieving, and mixing with ZnCl2 solution at concentrations of 0, 200, 300, 400, and 500 ppm, followed by heating (using either oven or an autoclave) and drying. The analysis included determination of total chlorophyll, phenolic, flavonoid, zinc, and andrographolide content. DPPH and FTC assays were employed to evaluate antioxidant activity. The results showed that increasing ZnCl2 concentration up to 300 ppm enhances chlorophyll, phenolic, flavonoid, zinc, and andrographolide content. Higher concentrations of ZnCl2 in the oven resulted in decreased lipid peroxidation inhibition (LPI) of Sambiloto simplicia powder, whereas using an autoclave led to increased LPI. Furthermore, higher ZnCl2 concentrations, up to 400 ppm, corresponded to increased DPPH radical scavenging activity. Lipid peroxidation inhibition activity correlated with andrographolide, zinc, and total phenolic contents. Conversely, DPPH radical scavenging activity strongly correlated with total phenolic, total flavonoid, Zn, chlorophyll, andrographolide content.
Synthesis of Linoleic Acid of Conjugated Isomers from Sesame (Sesamum Indicum) Seed Oil: Its Use and Effect in a Microstructured Product Type Oil-in-Water Emulsion
Authors: Brewer David Ramírez- , Palencia Luis Madrid- , Rodríguez Luis Monroy- , Martínez Somaris Quintana- , Zapateiro Luis A. García-
Published: September 2024

The development of functional foods is an area of great interest and innovation in the food industry. The use of conjugated linoleic acid (CLA) in food formulations has been growing in recent years due to its multiple health benefits. In this study, conjugated linoleic acid was obtained from sesame oil, and its use in the formulation of oil-in-water food emulsions was evaluated. Conjugated linoleic acid (CLA) was synthesized from the linoleic acid present in sesame oil using the alkaline isomerization method using proplyeneglycol as a solvent. The effect of alkali concentration (NaOH) and reaction time on the conversion of linoleic acid to CLA was evaluated. A 96.6% conversion of CLA was obtained with a NaOH concentration of 7% and a reaction time of 2 h. Emulsions were prepared using CLA as oil phase and soy lecithin, tween 80, carboxymethylcellulose as emulsifying agents. Emulsions with mixtures of carboxymethylcellulose and tween 80 were stable, presenting a non-Newtonian fluid behavior of pseudoplastic type (n<1). The Ostwald-de-Waele model shows an optimal fit to the experimental data of apparent viscosity (R2>0.99 ), and its microstructural characterization shows a homogeneous particle distribution. These results show that the alkaline isomerization process using propylene glycol as a solvent is an excellent alternative for the synthesis of CLA from vegetable oils such as sesame oil and its application in the development of microstructured products such as functional emulsions, and their subsequent application in the development of new food products with beneficial health characteristics.
Nutritional, Bioactive, and Health Potential of Pomelo (Citrus maxima): An Exotic Underutilized Fruit
Authors: Sharma Simple , Singh Barinderjit , Kaur Gurwinder , Srivastava Yashi , Sandhu Rubrinder Singh
Published: September 2024

Pomelo scientifically known as Citrus maxima belongs to the family Rutaceae and is one of the largest fruits among citrus varieties. Mainly pomelo comes in different flesh colors such as red, pink, light pink, and white. The principal pomelo fruit polyphenols are phenolic acids, flavonoids, anthocyanins, and tannins. Pomelo fruit generates a large number of wastes including peel, pomace, and seeds which are comprised of bioactive compounds. The bioactive compounds carried in waste improve health functionalities. The hesperidin, narirutin, naringin, and their aglycone (naringenin), which have traditionally been acknowledged to constitute a characteristic component of pomelo, are the fruit's major constituents. Also, pomelo fruit juice is high in vitamins A and C, and the peel offers high protein, carbohydrate, and mineral content. Pomelo production and processing of different byproducts have become a perfect and long-lasting resource for agriculture and the food industry. The wastes loaded with immense essential components in pomelo have great importance in terms of human health. To have unique goods, to increase high consumer acceptability, and to have health advantages, this work gives a summary of recent advancements made to date with nutritional benefits, bioactive elements, and health benefits of pomelo fruit.
Association Between Depression Levels and Body Weight and Dietary Habits in a Sample of the Saudi Population: A Cross-Sectional Study
Authors: Alyamani Reema Abdulrahman Saad , Alhussieni Jawaher Ahmed Abdullah , Alghashmari Muruj Matuq Mansi , Alkhozai Raghad Muslim Salem , Alsulami Renad Ayyad Owaid , Sab Shaima Zaki Mahmoud , Alamri Reham Abdullah Ali , Almuraee Areej Abdulhamid Hamdan , Bakr El-Sayed Hamed Ali , Qadhi Alaa Hatim Hassan , Alhassani Walaa Essam Mohammed , Alkholy Sarah Omar Fathi , Azzeh Firas Sultan Ibrahim , Almehmadi Awatif Musallam Salem , Awlya Ohaad Fahd Abdulaziz
Published: September 2024

Background and Objective: Depression is a pervasive mental health concern that can negatively affect individuals' physical and emotional well-being. This study aimed to explore the link between depression levels and body weight, and to evaluate the impact of an individual's nutritional status. Materials and Methods: A cross-sectional study with a random sampling technique employed (n =710 people from the Saudi population). The data were collected via an online survey in November 2022. Data were collected using a self-administered questionnaire, including sociodemographic data, dietary habits, weight data, and some food items associated with stressful eating. Depression, Anxiety, and Stress Scale (DASS-21) were applied to assess depression levels among participants (n = 710). Results: Data indicated that depression is widespread among the Saudi population, with varying degrees of severity. Moderate levels of depression represent 28.59% of Saudi society, while the Saudi population that suffered from severe depression levels reached 14.23% of our total sample population. Depression was positively and significantly correlated with eating behaviors and body mass index. Depression significantly increased with age. Conclusion: The findings indicate a significant correlation between depression, eating behavior, body mass index, and diet. The evidence supported a connection between higher body weight and depression. This suggests the need for interventions to reduce depression and obesity rates and promote a healthier society.
CONTRIBUIÇÕES TEÓRICO-CRÍTICAS DA INTERSECCIONALIDADE:
Authors: Silva dos Santos Pereira Bárbara , Cristina Gonçalves Graziela
Published: September 2024

Esta é uma resenha sobre a obra "Interseccionalidade", publicada no ano de 2021 pela parceria entre Patricia Hill Collins e Sirma Bilge, na qual as autoras desenvolvem o conceito de interseccionalidade e elucidam questões sobre sua utilização. Seria a interseccionalidade um método de pesquisa, uma ferramenta de análise ou uma vertente do feminismo? Quais são os usos da interseccionalidade e suas principais contradições? Esses questionamentos apontados na obra são uma valiosa contribuição teórico-crítica na busca da compreensão das opressões e problemas sociais, capturando a dinâmica existente entre os eixos de subordinação. A obra busca entender como raça, classe, gênero, capacidade física, nacionalidade, sexualidade, status de cidadania, etnia, faixa etária e demais categorias desvelam a complexidade do corpo como construção social. Em síntese, este é um livro que provoca uma imersão nas complexidades da interseccionalidade, sobretudo, na sua função enquanto ferramenta capaz de desvendar os mecanismos de opressão e promover a justiça social.
YOUTUBE E A PRODUÇÃO DAS INFÂNCIAS:
Authors: Salazar Guizzo Bianca
Published: September 2024

A concepção de infância tomou novos rumos no Brasil especialmente a partir do século XX quando mais intensamente passou-se a compreender as necessidades específicas e peculiares das crianças.  Ao mesmo tempo, percebe-se a grande visibilidade que as crianças passaram a ter na contemporaneidade. Um destes espaços de visibilidade é o YouTube.  Tomando este espaço como educativo, este artigo tem como objetivo analisar a partir de um canal do YouTube protagonizados por crianças quais representações de gênero, articuladas às infâncias, são veiculadas e propagadas. Metodologicamente foi realizada uma análise cultural a partir da perspectiva teórica dos Estudos Culturais pós-estruturalistas, valendo-se especialmente dos conceitos de representação e de pedagogias culturais. Os resultados apontaram que há reiterações no que diz respeito aos scripts de gênero, mas também há rupturas, já que meninos e meninas têm a possibilidade de realizar ações e utilizar linguagens que são associadas tanto às feminilidades, como às masculinidades.
ENTREVISTA: Processos educativos, cultura e educação – redesenhando o mapa no diálogo com Maria Elena Gonzalez Alfaya
Authors: Frangella Rita de Cássia
Published: September 2024

Trata-se de entrevista com a professora Maria Elena Gonzalez Alfaya, professora da Universidad de Córdoba/Espanha sobre o projeto “Córdoba com ojos de infância”, desenvolvido a partir da Red Infantil Escuela-Centro del Profesorado-Universidad/RIECU que articula docentes da Universidad de Córdoba em sua atuação com estudantes na formação de professores/as, o Centro de Formación Continuada del Profesorado e professores/as de Educação Infantil da Municipalidade de Córdoba, a partir da colaboração entre essas três instituições de formação de professores/as. Dele desdobra-se o “Mapa de experiências educacionais: Córdoba com olhos de infância”. A conversa, a partir da análise da experiência em debate, reflete sobre educação, cultura, diferença na educação das infâncias e na formação de seus educadores, discute as infâncias em suas potencialidades criativas, no diálogo com artefatos culturais que se dão a ler às crianças que, de forma instigante, os problematizam e abrem possibilidades dialógicas e interculturais, implicando na proposição de uma educação com as crianças, como sujeitos desses processos.
Beyond the imaging evaluation of fractures of the lateral process of the talus: Let’s not forget concomitant injuries
Authors: Lindner Cristian , Reyes Pedro , Molina Eduardo , Olave Andrés
Published: September 2024

Fractures of the lateral process of the talus (FLPT) are uncommon fractures that represent a clinical challenge. Traditional radiological classification systems rely predominantly on radiographic findings. However, due to the high rate of FLPT misdiagnosis and the limited accuracy in evaluating concomitant talar injuries through plain radiographs, novel imaging classification systems have been developed that aim to enhance the diagnosis of concomitant talar injuries, thereby optimizing patient management and reducing the incidence of long-term complications.
Investigating the effect of limited spectral information on NIRS-derived changes in hemoglobin and cytochrome-c-oxidase concentration with a diffusion-based model
Authors: Leadley Georgina , Cooper Robert J. , Austin Topun , Hebden Jeremy C. , Bale Gemma
Published: September 2024

This paper investigates the theoretical capability of near-infrared spectroscopy (NIRS) systems to accurately measure changes in the oxidation state of cerebral cytochrome-c-oxidase (CCO) alongside the hemoglobins, for a deeper understanding of NIRS limitations. Concentration changes of oxy and deoxyhemoglobin (HbO and HbR) indicate the oxygen status of blood vessels and correlate with several other physiological parameters across different pathologies. The oxidation state of CCO indicates cellular energy usage efficiency through oxidative metabolism, potentially serving as a biomarker for brain and other tissue disorders. This study employs an analytical model based on the diffusion equation and statistical analyses to explore the dependency of estimated concentration changes on various systematic parameters, such as choice of wavelengths, spectral bandwidth, and uncertainties in extinction coefficient (ε) and differential pathlength factor (DPF). When there is a 10% uncertainty in DPF and ε, errors were found to be highly dependent on the number of discrete wavelengths, but not on their bandwidth if appropriate considerations are taken to account for it.
Ultra-large mode field area single-mode all-solid anti-resonant fiber with open arc elements in the cladding
Authors: Gao Wei , Wang Xing , Ding Feifan , Hou Donglian , Lou Shuqin
Published: September 2024

What we believe to be a novel ultra-large mode field area (MFA) single-mode all-solid anti-resonant fiber (ARF) is proposed. Different from the large mode area (LMA) all-solid ARF with double layers of rods in the cladding, the proposed fiber utilizes open arc elements in the second layer instead of circular rods to simultaneously achieve the ultra-large MFA and high single-mode performance. Especially, the outer diameter (OD) of the fiber can be efficiently decreased in comparison with other LMA fibers with the same MFA. Through the combination of enlarging core diameter and adjusting the distance of the two layers of anti-resonant elements to expand the MFA, an ultra-large MFA of 15647 µm2 can be achieved at the wavelength of 1.064 µm, which is 2 times that of the largest MFA of the previously reported all-solid ARF. The ratio of the lowest loss of higher-order modes to the loss of the fundamental mode can reach up to 23797 and thus high single-mode performance can be simultaneously implemented. Moreover, the OD of the designed fiber is only 578 µm, which is almost a quarter of that of the previous rod-type photonic crystal fiber and the mainstream large-pitch fiber (approximately 1.5-2 mm). To the best of our knowledge, it is the smallest OD among the currently reported ultra-LMA fibers with an MFA greater than 10000 µm2. In addition, the tolerance to the change of fiber parameters is also discussed, demonstrating that the proposed fiber has a wide parameter tolerance range. Numerical results show that the all-solid ARF will be a great candidate for the future development of ultra-large MFA fiber.
Reconstruction of the opto-mechanical properties of the intervertebral disc with photoacoutic imaging
Authors: Capart Antoine , Allais Roman , Wojak Julien , Boiron Olivier , Da Silva Anabela
Published: September 2024

The intervertebral disc (IVD) is an essential component of the spine, serving as a shock absorber that enables flexibility and movement. Due to aging, the IVD undergoes degeneration, characterised by dehydration, which can lead to conditions like degenerative disc disease (e.g. herniated discs, spinal stenosis), resulting in pain, stiffness, and nerve damage. This degeneration primarily stems from changes in its intrinsic composition, in terms of water and collagen content, the main chromophores. Quantitative photoacoustic imaging is explored as a method for assessing the state of the disc. A numerical study was conducted using a digitised pig’s disc and opto-mechanical properties extracted from the litterature, with measurement configurations compatible with experimental setups. A non-linear model-based reconstruction approach was implemented, utilising the adjoint variables method to express gradients, and Monte Carlo simulations to solve the Radiative Transfer Equation involved in the forward and adjoint problems. Various scenarios were studied and a method that does not rely on the prior knowledge of the Grüneisen coefficient was proposed. The results demonstrate the feasibility of using photoacoustic measurements to assess the IVD’s composition, achieving significantly improved quantification compared to conventional methods.
Determinants of stroke among adult hypertensive patients on follow up in Addis Ababa public hospitals, Ethiopia: A case control study
Authors: Teshome Feyisa , Baye Bayisa Abdissa , Wili Wekashi , Ifa Meseret , Kune Guta
Published: September 2024

Background

Stroke is a non-communicable disease that causes sudden global or focal neurological disorders. It is one of the major public causes of morbidity and mortality in low- and middle-income countries, including Ethiopia. Early identification of the determinants and prompt intervention remains critical to reduce morbidity and mortality from stroke.

Objective

The study aimed to identify determinants of stroke among adult hypertensive patients on follow up in Addis Ababa public hospitals, Ethiopia.

Methods

Unmatched case-control study design was conducted among 326(109 cases and 217 controls) study participants in Addis Ababa public hospitals from September 1–30, 2021. The cases were adult hypertensive patients who developed a stroke and the controls were adult hypertensive patients. The study participants were selected by consecutive sampling technique. Pretested structured interviewer assisted questionnaire and checklist were used to collect data. Data were entered into Epi data version 3.1; exported and analysed by SPSS version 23. All independent variables with p-value < 0.25 in the bi-variable logistic regression analysis were entered into multivariable logistic regression analysis. Finally, variables with p-value <0.05 were considered as determinants of the stroke.

Results

In this study, current cigarette smoker(AOR = 5.55, 95% CI: 2.48, 12.43), current alcohol drinker(AOR = 4.27, 95% CI: 1.94, 9.38), medication non-compliance(AOR = 3.23, 95% CI: 1.62, 6.44), uncontrolled systolic blood pressure (AOR = 3.42, 95% CI: 1.64, 7.16), uncontrolled diastolic blood pressure(AOR = 4.29, 95% CI: 2.06, 8.93), high low density lipoprotein(AOR = 6.89, 95% CI: 3.57, 13.35) and diabetic mellitus(AOR = 3.25, 95% CI: 1.58, 6.69) were more likely to develop a stroke.

Conclusion and recommendation

Cigarette smoking, alcohol use, non-adherence to medication, uncontrolled systolic pressure, uncontrolled diastolic blood pressure, high low-density lipoprotein, and diabetic mellitus were determinants of stroke. Providing health education about lifestyle changes and the consequences of hypertension at all follow-up is very important.
The effects of icon design features on user perception and preference: A case study of icons for Covid-19
Authors: Lujie Deng , Lin Chunhua , Liao Qiong , Qiu Shuicai
Published: September 2024

The objective of this study is to evaluate users’ perceptions and preferences on the design features of the COVID-19 prevention promotion icon from the perspective of users’ aesthetic and perceptual needs. In this study, 120 officially published icons from 24 countries and regions were collected from online platforms for ranking tests, and then the top-ranked icons were subjectively rated by the semantic differential method. By evaluating the quality of users’ perceptions of multiple semantic dimensions of icons, we extracted the perceptual semantic words that users valued as the main icon design features. Spearmen correlations were applied to derive possible correlations between user rankings and semantic scales, and a Friedman test was also conducted to determine the true differences in user perceptions and preferences for different styles of icons. Factor analysis was conducted to extract six perceptual words that influence the design features of the COVID-19 prevention promotion icon. The methodology adopted in this study facilitated the screening of design features related to icon effectiveness, and the findings show that “Interesting,” “Simple,” “Familiar, “Recognizable,” “Concrete,” and “Close(semantic distance)” are the key features that influence users’ perception and preference of COVID-19 icon design. The results of this study can be used as the basis for designing and improving publicity icons for preventive measures in COVID-19, and the methods adopted in this study can be applied to evaluate other types of icon design.
A real-world evaluation of the clinical benefits of improved sound processor technology among Chinese cochlear implant users: A focus on Cochlear Nucleus 7
Authors: Deng Xiaocong , Wu Chenjiong , Wu Lin , Lu Jiyun , Zhang Jin
Published: September 2024

Real-world evidence is increasingly used to support clinical and regulatory decisions globally and may be a useful tool to study the unique needs of cochlear implant users in China. The ability to recognize and understand speech in noise is critical for cochlear implant users, however, this remains a challenge in everyday settings with fluctuating competing noise levels. The Cochlear™ Sound Processor, Nucleus® 7 (CP1000), includes Forward Focus, a spatial noise algorithm aimed to improve speech-in-noise performance, and Made for iPhone/iPod/iPad functionality. We conducted a prospective, single-center, open-label, within-participant, real-world evidence investigation in participants with cochlear implants. The primary objective of this study, conducted in China, was to compare speech perception in spatially separated dynamic noise with the Nucleus 7 to the recipients’ current older Cochlear Sound Processor, including the Freedom and Nucleus 5 sound processors. A follow-up study monitored participants from the initial study up to 12-months post the fitting of their Nucleus 7 and investigated hearing ability, satisfaction, and usability of the device via a questionnaire. Forty participants were included in the initial study (age-range 3 to 49 years) and 29 continued to the follow-up study (age-range 5 to 28 years). The participants were heterogeneous in terms of age, cochlear implant experience, and duration of hearing loss. Nucleus 7 significantly improved participant speech recognition performance in noise by 7.54 dB when compared with the participants’ current older sound processor (p<0.0001). Overall satisfaction with Nucleus 7 was 72%. Satisfaction in different hearing contexts ranged from 93.1% for understanding a 1:1 conversation in a quiet setting, 62.1% for understanding on the phone, to 34.5% hearing in complex noisy situations. The study demonstrated the benefits of the Nucleus 7 sound processor across different hearing environments in a Chinese population and showed improved hearing ability, usability, and satisfaction in a real-world every-day environment.
The HIV-1 capsid serves as a nanoscale reaction vessel for reverse transcription
Authors: Jennings Jordan , Bracey Harrison , Hong Jun , Nguyen Danny T. , Dasgupta Rishav , Rivera Alondra Vázquez , Sluis-Cremer Nicolas , Shi Jiong , Aiken Christopher
Published: September 2024

The viral capsid performs critical functions during HIV-1 infection and is a validated target for antiviral therapy. Previous studies have established that the proper structure and stability of the capsid are required for efficient HIV-1 reverse transcription in target cells. Moreover, it has recently been demonstrated that permeabilized virions and purified HIV-1 cores undergo efficient reverse transcription in vitro when the capsid is stabilized by addition of the host cell metabolite inositol hexakisphosphate (IP6). However, the molecular mechanism by which the capsid promotes reverse transcription is undefined. Here we show that wild type HIV-1 virions can undergo efficient reverse transcription in vitro in the absence of a membrane-permeabilizing agent. This activity, originally termed “natural endogenous reverse transcription” (NERT), depends on expression of the viral envelope glycoprotein during virus assembly and its incorporation into virions. Truncation of the gp41 cytoplasmic tail markedly reduced NERT activity, suggesting that gp41 licenses the entry of nucleotides into virions. By contrast to reverse transcription in permeabilized virions, NERT required neither the addition of IP6 nor a mature capsid, indicating that an intact viral membrane can substitute for the function of the viral capsid during reverse transcription in vitro. Collectively, these results demonstrate that the viral capsid functions as a nanoscale container for reverse transcription during HIV-1 infection.
ENTRE CURADORAS/ES E CURANDEIRAS/OS
Authors: Soares Mayara Ruth Nishiyama , Miranda Luciana Lobo , Oliveira Marta Clarice Nascimento , Sousa Bruna Ribeiro de
Published: September 2024

Este relato parte de uma pesquisa de mestrado que discutiu como jovens pesquisadoras/es enunciavam sobre as questões de gênero que atravessavam seu cotidiano escolar. Assim, a partir da criação de um grupo de pesquisa composto por  secundaristas de uma escola pública, enfocamos a articulação entre gênero e arte, e, com isso, germinamos a CURA(DOR)IA. Em interlocução com a Pesquisa-Inter(in)venção e a perspectiva do PesquisarCOM, o objetivo deste relato é discutir o dispositivo artístico CURA(DOR)IA, produzido como culminância de uma pesquisa participativa com jovens pesquisadores/as do seu cotidiano escolar em uma periferia de Fortaleza/CE. Destacamos duas cenas em que essas vivências são demarcadas, percebendo singularidades acerca do que a juventude daquele território traz com relação às experiências permeadas por essas discussões. Pontuamos o encontro como um dispositivo de abertura para produção de modos de vida mais inventivos, vislumbrando na diferença e na interface desta com a arte uma via a se seguir para pensar possíveis transgressões no debate.
OS EFEITOS DAS REDES SOCIAIS NA SUBJETIVIDADE E NOS MODOS DE RELAÇÃO COM O CORPO ENTRE JOVENS UNIVERSITÁRIOS
Authors: Patussi Andressa , Luis Schuck Anderson
Published: September 2024

O presente artigo teve como objetivo compreender os efeitos das redes sociais na subjetividade e relações com o corpo entre jovens universitários/as, considerando possibilidades de resistência aos modos de controle exercido na relação com as mídias digitais. A produção das informações envolveu a resposta de um questionário e realização de dois grupos focais, envolvendo 30 jovens universitários do curso de psicologia de uma universidade da região oeste de Santa Catarina. As análises contemplaram aspectos da relação com as redes sociais (tempo e contexto do uso), a produção de uma colonização digital, a reflexão sobre o caráter performáticos dos corpos em contextos de visibilidade e exclusão, e os efeitos nas subjetividades a partir de cenários produtores de pós-verdade e de incitação ao consumo. Assim, a coletivização de reflexões pode contribuir para uma maior problematização das informações que os jovens consomem e buscam nas redes sociais, ampliando possibilidades de resistência à normalização e padronização dos corpos.
DIGITALIZATION OF IRRIGATION SYSTEMS FROM WATER MANAGEMENT MAPS
Authors: Tejkl Adam , Kavka Petr
Published: September 2024

With the increasing intensity of evapotranspiration caused by the changing climate, there is a growing need for water. This is especially true in locations where water-intensive vegetables are grown in intensive agriculture. Historically, irrigation systems were built in many intensive agriculture areas in Czechia, but they fell out of use, and evidence of their location was lost. However, Water Management Maps, which were only issued in paper form and have never been fully digitized, can provide evidence about the location of these large-scale irrigation systems. In this paper, we present a method for digitizing irrigation systems using the segmentation and classification of individual segments in the ArcGIS environment. The resulting raster is converted to polygons and is blended with the Land Parcel Identification System layer, resulting in a layer of irrigated land. Two statistical analyses were performed on this layer: statistics of the areas corresponding to the individual source watercourses, and statistics of the type of source.
Advanced Perturb and Observe Algorithm for Maximum Power Point Tracking in Photovoltaic Systems with Adaptive Step Size
Authors: Amal ZOUHRI
Published: September 2024

Maximum power point tracking (MPPT) algorithms are commonly used in photovoltaic (PV) systems to optimize the power output from the solar panels. Among the various MPPT algorithms, the perturb and observe (P&O) algorithm is a popular choice due to its simplicity and effectiveness. However, the basic P&O algorithm has some limitations such as oscillations and steady-state error under rapidly changing irradiance conditions. The enhanced algorithm includes a modified perturbation step and a dynamic step size adjustment scheme. This reduces the oscillations and improves the tracking accuracy. In the dynamic step size adjustment scheme, the step size is adjusted based on the rate of change of the PV output power. This improves the tracking performance under rapidly changing irradiance conditions. In order to prove the performance of the designed control algorithm, we will test it under simple climatic conditions of fixed temperature (30°C) and variable irradiation in the form of steps (500W/m² and 2000w/m²) and see the system response. The performance of the enhanced P&O algorithm has been evaluated using MATLAB simulations.
Enhancing Stock Price Prediction in the Indonesian Market: a Concave LSTM Approach with RunReLU
Authors: Diqi Mohammad , Ordiyasa I Wayan
Published: September 2024

This study addresses the pressing need for improved stock price prediction models in the financial markets, focusing on the Indonesian stock market. It introduces an innovative approach that utilizes the custom activation function RunReLU within a Concave Long Short Term Memory (LSTM) framework. The primary objective is to enhance prediction accuracy, ultimately assisting investors and market participants in making more informed decisions. The research methodology used historical stock price data from ten prominent companies listed on the Indonesia Stock Exchange, covering the period from July 6, 2015, to October 14, 2021. Evaluation metrics such as RMSE, MAE, MAPE, and R2 were employed to assess model performance. The results consistently favored the RunReLU-based model over the ReLU-based model, showcasing lower RMSE and MAE values, higher R2 values, and notably reduced MAPE values. These findings underscore the practical applicability of custom activation functions for financial time series data, providing valuable tools for enhancing prediction precision in the dynamic landscape of the Indonesian stock market.
Enhancing Early Childhood Problem-Solving Abilities through Game-Based Learning and Computational Thinking: The Impact of Cognitive Styles
Authors: Ningtyas Dhita Paranita , Setyosari Punaji , Kuswandi Dedi , Ulfa Saida
Published: September 2024

Children's understanding of solving problems related to early cognitive abilities with several levels of complexity makes children feel difficult, and students are less able to solve problems correctly according to the sequential order of how to do them. The main factor that causes low problem-solving abilities is the use of inappropriate learning strategies. So that children in the process of solving problems in a lesson also become less than optimal. This study explores the effects of computational thinking strategies with game-based learning compared to conventional approaches on early childhood problem-solving abilities, considering the cognitive styles of field-independent (FI) and field-dependent (FD) children. A quasi-experimental pretest-posttest nonequivalent control group design involved 60 children from Blitar Kindergarten. The experimental group received computational thinking instruction through game-based learning, while the control group followed conventional methods. Posttests followed a pretest established baseline abilities and an eight-week intervention. Data were analyzed using a two-way ANOVA, revealing significant improvements in problem-solving skills for the experimental group (p < 0.05). FI children outperformed FD peers, indicating cognitive style's impact on learning outcomes. An interaction effect between learning strategies and cognitive styles was identified, emphasizing the importance of tailored educational approaches. The study's findings suggest that computational thinking through game-based learning enhances critical thinking, creativity, and engagement in young learners. However, limitations such as a small sample size and short intervention duration highlight the need for further research. Future studies should involve diverse populations and longer interventions to understand the long-term effects better and optimize educational strategies for individual cognitive styles. These results underscore the potential of innovative educational methods in developing foundational skills essential for academic and life success.
Conceptualization of the Integrated Islamic Religious Education Curriculum: A Literature Study at Imam Hatip Schools Turkey and MAN Insan Cendekia Indonesia
Authors: M. Fajar Sidik  , Vrisko Putra Vachruddin  , Evi Fatimatur Rusydiyah  , Ani Setya Pertiwi  , Mugthi Alintya Darmawan
Published: September 2024

Purpose – The authors aim to compare Imam Hatip School (IHS) with MAN Insan Cendekia (MAN IC), two Islamic educational institutions that have successfully implemented an Islamic religious education curriculum integrated with general science.
Design/methods/approach – This study used a literature review research method that examined several sources and government documents in three languages. The data collection technique was conducted by extracting and evaluating information in articles that meet the inclusion criteria. Once extracted and evaluated, the authors analyzed and interpreted the data.
Findings – The integrated curriculum of Islamic education in IHSs aims to anticipate extreme, radical understandings and rejection of the state that implements the secular system. It will form the nature and attitude of tolerance among fellow citizens, allowing it to reduce social conflicts. The IHSs has implemented the integrated Islamic education curriculum by adopting a modern education system. The implementation of the integrated PAI curriculum at MAN IC aims to eliminate the paradigm and praxis of the dichotomy of science. MAN IC adopts an integrated Islamic religious education curriculum based on the traditional Islamic system with a mandatory policy to stay at a dorm for students, where religious activities are more emphasized when students are in the dormitory.
Research implications/limitations – This research still has limitations due to a limited literature review and verification study in closed terms on our respondent informants. Therefore, further research is required to deepen the examination in this study.
Originality/value – The findings in this study have included the aspects of policy, strategy, content or material development, and the implementation results of the integrated PAI curriculum in the two institutions. Those aspects build a socio-cultural identity, allowing it to develop the school in the realm of progress and achievement. The expectation is that this research can become an example for the development of Islamic Education Institutions in integrating the PAI curriculum.
Handlungsspielräume von Nichtregierungsorganisationen in acht Ländern
Authors: Donges Larissa , Sperfeld Franziska , Stolpe Fabian , Dolinga Sophie
Published: September 2024

Ambitionierter Klimaschutz ist eine gesamtgesell­schaftliche, komplexe Herausforderung, für die es das Zusammenspiel unterschiedlichster­ Akteur/innen braucht. Zivilgesellschaftlichen Organisationen kommt bei der Ausgestaltung von klimapolitischen Rahmenbedingungen und ­deren Umsetzung als treibende Kraft und ­kritische Stimme eine entscheidende Rolle zu. Wie ist es um ihre Beteiligungsrechte und -möglichkeiten bestellt?
Epidemiologi Perdarahan Saluran Cerna Pada Pasien Endoskopi di Rumah Sakit Umum Daerah Cut Meutia, Aceh Utara, propinsi Aceh
Authors: Ikhsan Maulana , Sayuti Muhammad , Ariyanda Iqbal , Akbar Teuku Ilhami Surya
Published: September 2024

Background: Gastrointestinal bleeding is one of the main cause of death worldwide. For decades, the prevalence between lower gastrointestinal bleeding and upper gastrointestinal bleeding is constant. However, latest study showed that this may change due to the invention of new medication that prevent upper gastrointestinal bleeding. The epidemiology of gastrointestinal bleeding is important to plan the future promotion and prevention in the risk group and also to understand the distribution of the patient and their risk factor. The shortage of epidemiological data in developing countries makes the treatment of gastrointestinal bleeding became more challenging.Methods: This study is a retrospective study that aims to depict the epidemiology of gastrointestinal bleeding in patients who did gastroscopy or colonoscopy in Cut Meutia general hospital in North Aceh, Aceh Province. We analyze the medical record of the required patients in the interval of January 2019 to August 2021.Result: The incidence of lower gastrointestinal bleeding is higher than upper gastrointestinal bleeding. Female patients are dominant in develop gastrointestinal bleeding and elderly is the most common age that develop gastrointestinal bleeding.Conclusion : In general, the epidemiology of gastrointestinal bleeding in Cut Meutia general Hospital in North Aceh shares the same tendency with the incidence of gastrointestinal bleeding in many countries in the world, but there are several finding that differ such as high incidency of gastritic tumor and high incidency of gastritic tumor in younger age in male.
Transformación del derecho a decidir: análisis a la despenalización del delito de aborto en Colombia y derechos de la mujer
Authors: Sierra Zamora Paola Alexandra , Daza Gonzalez Alfonso , Daza Lora Santiago Andrés
Published: September 2024

Se estudia en este artículo la despenalización del delito de aborto en el Código Penal colombiano desde un enfoque de derechos humanos. Este análisis conlleva que se califique el aborto como derecho fundamental de la mujer. En cuanto a los métodos de investigación, se emplea un enfoque cualitativo, basado en el análisis de  contenido de fuentes primarias y secundarias, recopilando y examinando críticamente la normativa legal, los fallos judiciales y la literatura académica pertinente para fundamentar su argumentación a favor de la despenalización del aborto. Lo anterior se centra en la construcción de un marco teórico-jurídico que sitúe el debate en torno al aborto en el contexto de los derechos de la mujer. La pregunta que se pretende resolver es: ¿cuál es el impacto de la jurisprudencia constitucional e internacional en la protección de los derechos de las mujeres en relación con el aborto en Colombia?
Green synthesis, characterization and biological activity analysis of silver nanoparticles from commercially available root powder of Picrorhiza kurroa Royle ex Benth.
Authors: Agrawal Shreya , Negi Nikita , Bhandari Neha , Negi Prachi , Saklani Pooja
Published: September 2024

Picrorhiza kurroa Royle ex Benth., a medicinal plant native to the alpine regions of the Himalayas, is renowned for its diverse therapeutic properties. Recently, green-synthesized silver nanoparticles have gained attention for their potential in pharmaceutical and industrial applications. In this study, silver nanoparticles (Pk-AgNPs) were synthesized using commercially available root powder of P. kurroa. The objective was to evaluate their potential biomedical applications by assessing their antioxidant properties and cytotoxicity. The Pk-AgNPs were characterized using Scanning Electron Microscopy (SEM) and Fourier-Transform Infrared Spectroscopy (FT-IR), which revealed their morphology and functional groups. The Total Antioxidant Capacity (TAC) of methanolic root extract of P. kurroa (PkRE) and the Pk-AgNPs was determined using the Phosphomolybdenum method. The results indicated that the antioxidant activity of PkRE was higher than that of the Pk-AgNPs. Moreover, the activity increased with concentration, ranging from 20 µg/mL to 120 µg/mL, demonstrating their capability to eliminate harmful free radicals. The cytotoxicity of PkRE and Pk-AgNPs was evaluated using the MTT assay against the SV40 T-antigen-containing HEK293T cell line, derived from human embryonic kidney 293 cells and the L929 cell line, a mouse fibroblast cell line. The results demonstrated dose-dependent cytotoxicity. L929 cells remained 100 % viable at concentration up to 200 µg/mL for PkRE and 100 µg/mL Pk-AgNPs. In contrast, HEK293T cells didn’t show 100 % viability even at a concentration of 50 µg/mL for both samples. This study highlights the potential use of PkRE and Pk-AgNPs as antioxidants. However, the cytotoxicity findings suggests that they may be harmful to humans if consumed orally, though they could be suitable for use in other organisms. This paves the way for further research into the application of AgNPs synthesized from P. kurroa in biomedical and pharmaceutical domains as well as in veterinary sciences.
The Limits of Plato’s Test
Authors: Meadows Katherine
Published: September 2024

Aristotle is often taken to define priority in being in Metaphysics Δ.11, where he says that those things are prior in being which “admit of being without other things, while these others cannot be without them: a division which Plato used” (1019a3-4). But Aristotle’s pattern of arguments about priority – some of which use Plato’s Test and others of which use distinct, causal tests – looks puzzling if Plato’s Test is his definition. This paper offers a new interpretation of Δ.11 on which it offers a guide to the Aristotelian use of Plato’s Test, given that being is said in many ways, rather than endorsing it as Aristotle’s own definition of priority. This reading illuminates Aristotle’s pattern of arguments in the corpus – explaining why Aristotle uses Plato’s Test in some cases and departs from it in others – and suggests a plausible story about how these arguments were shaped by engaging with Plato.
Knockdown of HCK promotes HREC cell viability and inner blood–retinal barrier integrity by regulating the AMPK signaling pathway
Authors: Chen Lu , Lin Chengmin
Published: September 2024

Diabetic retinopathy (DR), a major complication of diabetes causing blindness, is characterized by retinal damage due to capillary degeneration and vascular leakage. Current treatments are not fully effective, highlighting the need for searching new therapeutic targets. Hematopoietic cell kinase (HCK), a protein involved in various diseases, has been identified as a potential biomarker in DR, but its role in disease progression requires further investigation. Here we investigated the role of HCK in DR and its potential mechanism. We found the expression of HCK increased under the stimulation of high glucose (HG) in human retinal capillary endothelial cells (HRECs). Knockdown of HCK can improve HREC cell viability and the integrity of the internal blood–retinal barrier. HCK depletion suppressed the AMPK pathway in HG-induced HRECs. In summary, HCK may be a potential target for the treatment of DR, which provides a theoretical basis for the development of new treatment strategies.
Antibacterial, antifungal, and phytochemical properties of Salsola kali ethanolic extract
Authors: Bashir Shimaa , Behiry Said , Al-Askar Abdulaziz A. , Kowalczewski Przemysław Łukasz , Emaish Haitham H. , Abdelkhalek Ahmed
Published: September 2024

The research into the use of plants as plentiful reservoirs of bioactive chemicals shows significant potential for agricultural uses. This study focused on analyzing the chemical composition and potency of an ethanolic extract obtained from the aerial parts (leaves and stems) of Salsola kali against potato pathogenic fungal and bacterial pathogens. The isolated fungal isolates were unequivocally identified as Fusarium oxysporum and Rhizoctonia solani based on morphological characteristics and internal transcribed spacer genetic sequencing data. The antifungal activity of the extract revealed good inhibition efficacy against R. solani (60.4%) and weak activity against F. oxysporum (11.1%) at a concentration of 5,000 µg/mL. The S. kali extract exhibited strong antibacterial activity, as evidenced by the significant inhibition zone diameter (mm) observed in all three strains of bacteria that were tested: Pectobacterium carotovorum (13.33), Pectobacterium atrosepticum (9.00), and Ralstonia solanacearum (9.33), at a concentration of 10,000 µg/mL. High-performance liquid chromatography analysis revealed the presence of several polyphenolic compounds (μg/g), with gallic acid (2942.8), caffeic acid (2110.2), cinnamic acid (1943.1), and chlorogenic acid (858.4) being the predominant ones. Quercetin and hesperetin were the predominant flavonoid components, with concentrations of 1110.3 and 1059.3 μg/g, respectively. Gas chromatography-mass spectrometry analysis revealed the presence of many bioactive compounds, such as saturated and unsaturated fatty acids, diterpenes, and phytosterols. The most abundant compound detected was n-hexadecanoic acid, which accounted for 28.1%. The results emphasize the potential of S. kali extract as a valuable source of bioactive substances that possess good antifungal and antibacterial effects, which highlights its potential for many agricultural uses.