bluuebunny/crossref_metadata_2025 huggingface dataset:
DA MODERNIDADE DE BAUDELAIRE À MODERNIDADE BRASILEIRA
Authors:   PUC Goiás, Cavalcante de Freitas Nayara , Fernando Perilo Vitoy Vitor ,   PUC Goiás
Published: November 2020

Resumo: a poesia do poeta francês Charles Baudelaire ressoou até a poesia brasileira. Isto porque Baudelaire é precursor do conceito de modernidade e os efeitos desta têm grande influência na formação cultural e acadêmica dos estudantes da contemporaneidade. Foi o poeta que em seus trabalhos promoveu a ruptura com o romantismo e incentivou os trabalhos que atualmente conhecemos. Objetivo: buscar investigar através da pesquisa as diversas formas literárias e demonstrar a influência baudelairiana na modernidade brasileira. Nesse sentido, pretendeu-se constituir um corpus com obras poéticas em perspectiva crítica e demonstrativa, com as vertentes artísticas de mesma temática e período histórico. Método: Foi realizado um estudo complexo de textos e documentos históricos inerentes ao período do modernismo baseados em uma pesquisa de revisão bibliográfica. Os procedimentos metodológicos utilizados nesse projeto permitiram captar uma variedade de fenômenos e situações que se construíram na realidade em estudo entre a modernidade de Charles Baudelaire e sua influência na lírica moderna brasileira. Resultados: Através das diversas fontes da pesquisa foi realizado um apanhado de influências de Baudelaire no Brasil, a começar pela sua aparição no Jornal do Comércio, no qual Félix Pacheco promoveu um verdadeiro revival baudelairiano; perpassando pelo poema de Vinicius de Moraes à Baudelaire presente em sua obra “Antologia Poética”. E por fim, o flanêur de Baudelaire, apresenta na poesia de Vinicius. Conclusão: Através de fontes bibliográficas disponíveis. Foi possível compreender a modernidade precursora de Baudelaire e seu processo estilístico, demonstrando sua chegada ao Ocidente, com enfoque no Brasil; analisar com maior propriedade a poética e prosa modernas de Baudelaire e Vinicius, pontuando as influências e contribuições artísticas do poeta francês nos escritos brasileiros; e trabalhar com leituras imanentes dos textos selecionados de modo a constituir uma visão do modernismo brasileiro, essencialmente influenciado por Baudelaire.
Desenvolvimento de aplicação web para classificação geotécnica de solos tropicais baseado na metodologia MCT
Authors: Marinho Mateus Santos , Egito Costa Stephanny Conceição Farias do , Almeida Hélder Conceição
Published: November 2020

As classificações geotécnicas possuem a finalidade de agrupar os solos por seus diferentes tipos, mediante seu comportamento para obras de engenharia. A metodologia MCT (Miniatura Compactada Tropical) foi criada por Nogami e Villibor (1981) para atribuir nomenclaturas de grupo apropriadas aos solos brasileiros e auxiliar nas obras rodoviárias. Este trabalho teve como objetivo principal desenvolver uma ferramenta computacional que permitisse obter a classificação de solos, utilizando a metodologia MCT, através de dados de entrada dos ensaios Mini-MCV e Perda de Massa por Imersão. A metodologia aplicada consistiu no desenvolvimento do sistema, empregando as tecnologias HTML, CSS, Javascript e a linguagem de programação de servidor PHP. Obteve-se, como resultado, uma aplicação web desenvolvida baseada no modelo cliente-servidor. Esse sistema gera uma tabela com um resumo dos parâmetros obtidos e uma página contendo os coeficientes e índices de classificação calculados, além da classificação final da amostra. Para validação da aplicação, foram utilizados os dados de amostras de solos ensaiadas por Venturini (2015) e os resultados gerados foram confrontados com a referência utilizada e de forma analítica. Através desses resultados, foi possível afirmar que a classificação de amostras de solo pela sistemática MCT por meio de um software foi alcançada e a aplicação desenvolvida é capaz de fornecer auxílio técnico necessário para profissionais de engenharia e correlatos, assim como, motivar maior empregabilidade da metodologia MCT.
A comunicação dos requisitos de desempenho ao consumidor do mercado imobiliário
Authors: Dalbosco Francieli Vargas , Reis Katiane Aline dos , Lantelme Elvira Maria Vieira
Published: November 2020

Os consumidores do mercado imobiliário envolvem-se poucas vezes durante a vida no processo de compra de imóveis. Durante esse processo, esses consumidores utilizam informações limitadas para avaliar o valor de um imóvel, em razão de não terem acesso a informações completas e por falta de conhecimento e experiência. As informações sobre a qualidade e desempenho de um imóvel no ato de venda são direito fundamental do consumidor, presente no Código de Defesa do Consumidor (CDC) e também são requisitos obrigatórios que constam na Norma Brasileira de Desempenho (ABNT, 2013). Assim, o objetivo desta pesquisa foi identificar a percepção dos envolvidos no processo de compra (corretores e clientes) quanto aos benefícios desta informação e as formas de comunicação mais adequadas para orientar o consumidor no processo de decisão de compra. A pesquisa é de cunho qualitativo realizada por meio de entrevistas em duas fases distintas. A primeira fase baseou-se na revisão da literatura e em entrevistas realizadas com corretores e especialistas da Norma de Desempenho. Na segunda fase foram entrevistados consumidores do mercado imobiliário, a fim de obter suas percepções sobre o tema. Os resultados indicam a importância do repasse de informações completas e claras dos imóveis ao consumidor. Sugere-se para pesquisas futuras verificar como as informações técnicas influenciam a tomada de decisão do consumidor no processo de compra e identificar como esta informação deve ser apresentada ao cliente.
Avaliação do escorrimento e da resistência à tração na compressão diametral de uma mistura tipo SMA com adição de cal cálcica e fibra de vidro tipo E
Authors: Basso dos Santos Maicon , Lemos Nogueira Matheus
Published: November 2020

Com a crescente demanda por estruturas que suportam elevados volumes de tráfego, excesso de carga, melhor desempenho e menor necessidade de intervenções para reparos ou manutenções, é necessário que novos materiais sejam estudados ou desenvolvidos para sanar tais necessidades. Dentre as misturas asfálticas usinadas a quente, pode-se destacar a Stone Matrix Asphalt (SMA) que foi desenvolvida e melhorada ao longo do tempo para atender rodovias com pesado volume de tráfego. Neste trabalho, foram analisados os efeitos da adição da cal hidratada sobre a resistência à tração da mistura SMA e o efeito da utilização da fibra de vidro tipo E na mitigação do escorrimento do ligante betuminoso. Utilizou-se ligante asfáltico modificado por polímero (CAP 60/85-E), fibra de vidro tipo E, areia artificial, agregado basáltico e cal. Os corpos de prova foram submetidos aos ensaios para definição dos parâmetros Marshall, ensaio de escorrimento (Schellemberg) e resistência à tração por compressão diametral. O teor de ligante foi fixado em 7% devido aos resultados obtidos nos parâmetros Marshall. No ensaio de escorrimento foi observado teor adequado para a mistura com 0,5% fibra de vidro. Já no ensaio de resistência à tração foi constatada perda de resistência do teor de 1,5% de cal quando comparado a 1%, entretanto ambos percentuais apresentaram resistência superior ao prescrito pela ET-DE-P00/031.
Uso de Técnicas de Mineração de Dados na Extração de Sequências de Navegação de Estudantes de um Massive Open Online Course (MOOC)
Authors: Souza Napoliana Silva de , Perry Gabriela Trindade
Published: November 2020

Estudantes têm objetivos, preferências e ações de interação que se diferenciam, e em MOOCs o comportamento navegacional pode ser útil para fazer descobertas sobre a aprendizagem. Nesse contexto, esse artigo relata uma pesquisa realizada com os propósitos de detectar as sequências de navegação de 906 estudantes de um MOOC com conteúdos ligados a disciplina de Química, e identificar os materiais educacionais mais acessados. Técnicas de mineração de dados educacionais foram empregadas, com aplicação do algoritmo Apriori. Os resultados mostraram 18 sequências frequentes, e indicaram que os conteúdos do primeiro módulo do curso receberam mais acessos.
Palavras-chave: MOOC. Mineração de dados. Padrões sequenciais.
Percepções de Docentes sobre as Tecnologias no Ensino em Saúde
Authors: Pereira Adriana Teixeixa , Sass Simeão Donizete , Gallian Dante Marcello Claramonte
Published: November 2020

Diante das atuais mudanças na educação notou-se um grande avanço das tecnologias em todos os níveis de ensino e em diversas áreas do conhecimento. Este artigo teve como objetivo refletir e discutir sobre o papel do docente frente às tecnologias no ensino em saúde. Esta pesquisa qualitativa pautou-se no método de História Oral de Vida. Foram realizadas dez entrevistas livres com os docentes do ensino em saúde de diferentes cursos (graduações, pós-graduações e cursos técnicos). A casuística foi composta por dois médicos, dois psicólogos, um biomédico, três pedagogos, um enfermeiro e um docente de tecnologia em saúde-hospitalar, atuantes em universidades públicas e privadas na cidade de São Paulo. Para análise dos dados, utilizou-se o método de Imersão e Cristalização, segundo a Abordagem Fenomenológica Hermenêutica. Como resultado explorou-se apenas uma única categoria temática: Os docentes frente à Tecnologia da Educação a Distância: problemas e desafios. Concluiu-se que a implementação dos recursos tecnológicos na Educação a Distância está em processo gradativo de mudanças de paradigmas educacionais; adaptação dos docentes­-discentes; necessidade de qualificação dos professores e falhas na infraestrutura das universidades.
Palavras-chave: Educação a distância. Tecnologias. Ensino em saúde.
Application of Ventilation Technology of Bamboo Houses in Modern High-Rise Buildings
Authors: Zhou Zijie , Xiao Yiqiang
Published: November 2020

The principle of L-shaped natural ventilation system of bamboo houses, traditional buildings in the hot-humid area of Lingnan, China, is now widely applied in the design of modern high-rise buildings. Taking the typical building case, the office building of Guangzhou Zhujiang Power Plant as an example, this article studies the natural ventilation system by the experimental method of combining actual measurement and simulation. It is concluded that the application benefits of the natural ventilation system in high-rise buildings can be improved by forming a complete ventilation path, increasing the area of air inlet and the distance between air inlet and air outlet.

 
AGRONOMIC PERFORMANCE OF CORN ON THE COB GROWN ON RESIDUAL ORGANOMINERAL FERTILIZATION USED IN INDUSTRIAL TOMATO CROP
Authors: ROCHA MARIELLA CAMARGO , SOUSA CLEITON MATEUS , DIAS GABRIEL JÚNIOR S. , CAIXETA MÔNICA MENDES A. , OLIVEIRA ANA PAULA SANTOS
Published: November 2020

The study evaluated the agronomic performance of green maize grown on residual organomineral fertilization used in the industrial tomato crop. The randomized block design was used, with three replications and eight treatments as follows: control (without fertilizer application); mineral fertilizer; cattle manure; organomineral with cattle manure + MAP (monoammonium phosphate); chicken manure; organomineral with chicken manure + MAP; broiler litter; and organomineral with broiler litter + MAP. All of those treatments were applied to the tomato crop that preceded the green maize crop. After the tomato harvest, maize was sown in the same tomato growing row. Growth variables of green maize plants and ears were evaluated. The green maize grown in areas with residues of chicken and cattle manure, used as fertilizers in the tomato crop preceding the maize crop, resulted in a number of commercial ears similar to when mineral fertilizer was used. The same similar results were obtained for ear quality and yield. The use of organic fertilizers in the industrial tomato crop presented high viability, which made possible to replace the use of mineral fertilizers in the subsequent green maize crop.
OFF-SEASON STRATEGIES TO IMPROVE SOIL PHYSICAL ATTRIBUTES IN A NO-TILL SYSTEM IN THE BRAZILIAN CERRADO
Authors: FERREIRA RANIER VIEIRA , MORAES TAVARES ROSE LUIZA , PAIVA FILLHO SILVIO VASCONCELOS , MARASCA INDIAMARA , SILVA ALESSANDRO GUERRA
Published: November 2020

In the central region of Brazil, sorghum and maize are considered viable crop alternatives to be cultivated during off-season periods, mainly for the production of grains in succession to the cultivation of soybeans and intercropping with brachiaria grasses. This study aimed to evaluate the physical soil qualities of the soil from an area with different off-season management histories (monoculture or agricultural intercropping). Maize, sorghum and brachiaria crops have been cultivated under no-tillage system. The experiment was conducted using a randomized complete block design, with four replications. The treatments included: monoculture or intercropping between sorghum and brachiaria (first off-season strategy) or maize and brachiaria (second off-season strategy). The following physical properties of the soil were evaluated: soil bulk density, porosity, soil resistance to penetration, soil moisture and texture and the contents of organic carbon, which were analyzed at 0-20, 20-40 and 40-60 cm deep. In the off-season, the cultivation of single brachiaria promoted a greater amount of dry matter when compared with sorghum- brachiaria or maize-brachiaria intercropping. The topsoil presented better physical quality when compared with the adjacent layers under no-tillage system. The use of brachiaria combined with sorghum or maize tends to improve the macro and microporosity of the soil.
NITROGEN RATES AND SOWING DATES INFLUENCE THE SEVERITY OF WHITE SPOT DISEASE AND GRAIN YIELD OF MAIZE
Authors: BERGHETTI JULIANO , SHEIDT BRUNO TABARELLI , CASA RICARDO TREZZI , COELHO ANTÔNIO EDUARDO , SANGOI LUIS , GONÇALVES MAYRA JULINE , LEOLATO LUCIELI
Published: November 2020

The objective of this study was to analyze the effects of nitrogen rates and sowing dates on the severity of white spot disease (WSD) in first season maize hybrids, and their correlation with relative chlorophyll content, thousand grain weight and yield. The experiment was set in a randomized block design with treatments arranged in split-split plots. Two hybrids were tested in the main plots: AG9025 PRO3 (super early) and 30F53 VYH (early). Two sowing dates were evaluated in the split plots: preferential (9/20/2016) and late (12/05/2016). Four nitrogen rates were applied in the split-split plots. Nitrogen rates were top-dressed at the V4, V8 and V12 vegetative stages. The relative chlorophyll content reading was performed at VT stage. The quantification of WSD severity was made at R6, using diagrammatic scale. The AG9025 PRO3 hybrid showed higher average WSD severity (17.7%) than the 30F53 VYH (9.3%). The preferential sowing date showed lower severity (2.2%) compared to the late sowing date (31.4%). There was a significant positive correlation between the disease severity and the relative chlorophyll content, thousand grain weight and grain yield, except for the 30F53 VYH hybrid on the late sowing date. The hybrid AG9025 PRO3 showed increase in WSD severity when the highest nitrogen rates were applied, on both sowing dates. The effect of N rates on WSD was not significant for the 30F53 VYH hybrid. The late sowing time generates greater disease severity. The AG9025 PRO3 hybrid is more susceptible and the severity of its white spot is increased with the increment in N doses. There is a positive correlation between the relative chlorophyll content, disease severity, yield and thousand grain weight.
Online News Article Analytics: An Alternative Method to Explore Seasonal Issues in National Parks
Authors: Yang Eunjung , Kim Jinwon , Sim Kyu-Won , Thapa Brijesh
Published: November 2020

Seasonality can affect the use of park resources and visitors’ experience in national parks. To understand seasonal issues, park managers have typically relied on survey-based studies that tend to be limited in sample sizes and data collection periods. The purpose of this study is to utilize online news article analytics as a complementary approach to find dynamic issues based on topic-modeling techniques in the context of South Korean national parks. A total of 12,994 online news articles were collected from a Korean search engine—NAVER. Results indicated common issues such as environmental degradation/protection, and visitor experience/ activity across all four seasons, along with distinctive issues for each season (e.g., fall foliage, park services, and protecting endangered species). Such findings can not only benefit managers in assisting the development of effective seasonal park management plans, but they can also promote visitors’ attention by providing dynamic seasonal issues in national parks.
The Impact of Syrian Refugees on the Turkish Labor Market
Authors: Isiksal Huseyin , Zhakanova Isiksal Aliya , Apeji Yossi
Published: November 2020

The civil war in Syria has destabilized the whole Middle East along with neighboring regions. In this respect, the impact of Syrian refugees on Turkish labor market is one of the most important contemporary issues discussed in Turkey. This issue has both political and economic significance. Deriving from this point, the aim of this study is to research the empirical relationship between the Labor Market Indicator (LMI) and the growing number of Syrian Refugees in Turkey (RS) by using time series analysis. The data employs monthly data for the period from January 2012 to August 2017. Results of the ARDL bounds test suggest that the Labor Market Indicator and the number of Syrian Refugees are in a long-run relationship. The Gregory-Hansen cointegration test with a structural break confirms the robustness of the ARDL bounds test of cointegration. The Kalman filtering approach was designed to investigate the dynamic relationship between the Labor Market Indicators and the growing number of Syrian Refugees. The results show that the increase in the number of Syrian refugees negatively affects the Labor Market Indicator in Turkey, which implies that the inflow of Syrians has negative effects on labor market outcomes such as employment and unemployment in the country. These results also confirm the postulation of general labor migration theory, which holds that an influx of refugees negatively affects labor market outcomes in the harboring country.
Parental Acceptability of HPV Vaccination for Adolescent Daughters and Associated Factors: A Cross-Sectional Survey in Bozhou, China
Authors: Suo Tonghui , Lu Qi
Published: November 2020

Purpose

This study aimed to investigate parents' acceptability of human papillomavirus (HPV) vaccination for their daughters and associated factors.

Methods

This cross-sectional study was conducted in a city in China with a sample population of parents with a daughter in middle school. Participants' demographic characteristics, knowledge level regarding HPV and the HPV vaccine, perspectives on the health belief model (HBM) constructs, social norms, and acceptability of the HPV vaccine were determined through self-administered questionnaires.

Results

Among the 523 parents who completed the questionnaire, 71.5% expressed willingness to have their daughters vaccinated against HPV infection and cervical cancer. Logistic regression analysis revealed higher acceptability in the participants with higher perceived severity of HPV infection (OR = 4.823, 95% CI = 2.683, 12.049), higher knowledge-assessment score (OR = 1.298, 95% CI = 1.055, 1.476), and higher perceived safety of the HPV vaccine (OR = 6.372, 95% CI = 3.856, 14.062). Parents influenced by social norms (OR = 4.959, 95% CI = 2.989, 14.386) and those who complied with physicians' recommendations (OR = 4.896, 95% CI = 1.936, 9.258) reported higher levels of acceptability.

Implications

Our results provide preliminary evidence on the need for health education programs and HPV vaccination campaigns. Future studies should focus on whether the factors associated with vaccination can increase parental acceptability of the HPV vaccine.
Factores asociados a supervivencia global al año y 5 años en mujeres con cáncer de mama metastásico atendidas en el Instituto Nacional de Enfermedades Neoplásicas entre los años 2009-2012
Authors:   ,   Universidad Peruana de Ciencias Aplicadas (UPC), Pichilingue-Febres Alejandra Fiorella , Arias Linares Miguel Ángel
Published: November 2020

Introducción: El cáncer de mama es la neoplasia más prevalente y la primera causa de muerte por cáncer en mujeres, global y localmente. Gran parte de la mortalidad es debida a enfermedad metastásica. El objetivo del estudio es evaluar qué factores se asocian a supervivencia global a cinco años en mujeres peruanas con cáncer de mama metastásico en el INEN 2009-2012. Métodos: Cohorte retrospectiva con análisis de supervivencia mediante revisión de historias clínicas. Se incluyó mujeres ≥18 años con adenocarcinoma de mama metastásico confirmado en el INEN entre enero 2009 y diciembre 2012. Se siguió hasta muerte o cinco años post-metástasis. Las probabilidades de supervivencia fueron comparadas mediante curvas de Kaplan-Meier y Log Rank. Hazard ratios crudos y ajustados (HRa) fueron obtenidos mediante regresión de Cox. Resultados: Se incluyeron 320 pacientes con edad promedio de 52.6 años. Mediana de seguimiento fue 569.5 días. La supervivencia global a los 5 años fue 16.6% (12.7-20.8%). Factores asociados a muerte por toda causa fueron ECOG 2-4 (HRa: 2.21; IC95% 1.65-2.97), metástasis cerebral (HRa: 1.90; IC95% 1.39-2.60), subtipos Her2 (HRa: 2.40; IC95% 1.74-3.29) y Triple-negativo (HRa: 2.37; IC95% 1.66-3.37), cirugía mamaria post-metástasis (HRa: 0.37; IC95% 0.25-0.56), quimioterapia (HRa: 0.51; IC95% 0.35-0.73), y radioterapia (HRa: 0.52, IC95% 0.39-0.71). Conclusiones: La supervivencia global de cáncer de mama metastásico en nuestro centro es menor a la reportada en otros países. Pobre estatus funcional, metástasis cerebral, subtipos inmunohistoquímicos Her2 y Triple-negativo se asociaron a mayor riesgo de muerte por toda causa. Cirugía del tumor primario aun después de metástasis, quimioterapia y radioterapia disminuyeron el riesgo de muerte.
A turizmus üvegházhatásúgáz-kibocsátásának és bruttó hozzáadott értékének kapcsolata Magyarországon
Authors: Mesteri Viktória , Kocsis Tímea
Published: November 2020

A globális klímaváltozás egyik oka az üvegházhatású gázok antropogén kibocsátása, amelyhez többek között a turizmus is hozzájárul. A tanulmány paraméteres és nemparaméteres eljárások segítségével elemzi az üvegházhatásúgáz-kibocsátás 1985 és 2017 közötti alakulását az I nemzetgazdasági ágban (szálláshely-szolgáltatás és vendéglátás). A szerzők a vizsgált üvegházhatású gázok összessége és ezen belül a fluorozott szénhidrogének, valamint a perfluorkarbon kibocsátása esetében igazolnak szignifikáns tendenciát. Azt is tanulmányozzák, hogy az 1995–2017-es időszakban milyen kapcsolat állt fenn az ág bruttó hozzáadott értéke és üvegházhatásúgáz-kibocsátása között a gázokat együtt és külön is tekintve. Eredményeik szerint az előbbiek vonatkozásában nincs szignifikáns kapcsolat, egyes gázok esetén viszont van. A turizmus (I) nemzetgazdasági ág hozzájárulása az ország gazdasági teljesítményéhez 1995 és 2017 között összegszerűleg szignifikánsan növekedett, de aránya a bruttó hozzáadott értékből 2017-ben csupán 1,86 százalékot tett ki. A nemzetgazdasági ág karbonhatékonyságában évente átlagosan 5,8 százalékos javulás volt megfigyelhető.
MENYOAL PROSPEK EKONOMI SYARI`AH DI INDONESIA
Authors: Mansyur Zaenudin
Published: November 2020

Optimisme terhadap prospek Ekonomi Syariah di masa akan datang semakin besar,setelah sistem ekonomi syariah ini berhasil melampaui krisis keuangan global pada tahun1998. Peluang yang diperoleh oleh sistem ekonomi syari`ah itu tidak boleh disikapi olehsubjeknya dengan membanggakannya, namun harus juga mempertimbangkan tantangan yangakan timbul di masa sekarang maupun masa yang akan datang. Tidak bias disangkalbahwa peluang semestinya menjadi dasar untuk melebarkan sayap justru bisa sajamenjadi sebuah tantangan yang berat bagi sistem ekonom syari`ah itu. Begitu jugasebaliknya, tantangan yang seharusnya menjadi tonggak untuk berhati-hati dalammengembangkannya justru menjadi peluang di masa-masa mendatang. Dengan melihatkenyataan ini setidaknya menjadi dasar yang kuat untuk dilakukan sebuah pengkajianterutama dalam mempersoalkan bagaimana prosfek yang utuh bagi sistem ekonomi syari`ahapakah sesuai harapan yang selama ini digembar-gemborkan keberhasilannya oleh pakarekonomi syari`ah atau justru sebaliknya akan bertahan dalam ruang tantangan yangtidak akan jelas kapan selesainya.
Meningiomas: criteria for modern surgical indications
Authors: Cappabianca Paolo , d’Avella Elena , Cavallo Luigi Maria , Solari Domenico
Published: November 2020

The contemporary management of meningiomas is the result of the continuous evolution of neurosurgical techniques, along with the refinement of dedicated instrumentations. Above all, it is the magnification of the surgical view, thanks to the microscope and the endoscope, and their advancements, which allowed the improvement of surgical outcomes, in terms of both extent of resection and morbidity rates. Because of the benign nature of the vast majority of meningiomas, complete tumor resection is curative, and it is the gold-standard treatment. However, in the case of high risk of surgical morbidity, a less aggressive surgical treatment may be justified, also upon tailored analysis of the meningiomas’ biological behavior and the improvements in postoperative strategies. The endoscopic technique plays a role, as a unique visualization tool or in combination with the microscope, in granting so-called maximum allowed resection. Considering the above, the most challenging task confronting modern meningioma surgery remains the selection of the most appropriate surgical approach, the latter greatly depending on location, anatomic tumor features, and relationships with critical neurovascular structures. Herein, we present a cogent analysis of the modern multifaceted indications for the endoscopic treatment of meningiomas, with a glimpse into the adjacent fields.
Potensi Tanaman Lokal sebagai Tanaman Obat dalam Menghambat Penyebaran COVID-19
Authors: Dewi Yuli Kusuma , Riyandari Baiq Amelia
Published: November 2020

COVID-19 (Corona Virus Disease of 2019) merupakan wabah penyakit yang menginfeksi saluran pernafasan pada manusia. Wabah ini tidak hanya terjadi di Indonesia, melainkan terjadi hampir di seluruh negara di Dunia. COVID-19 ini menjadi wabah yang meresahkan karena penyebarannya terjadi dengan sangat cepat melalui kontak antara manusia dengan manusia dan hingga saat ini belum tersedianya vaksin terhadap virus SARS-CoV-2 yang telah diuji klinis untuk mengatasi penyebaran virus ini. Salah satu upaya untuk mencegah penyebaran COVID-19 adalah meningkatkan sistem kekebalan tubuh (sistem imunitas) melalui asupan makanan yang kaya akan kandungan senyawa antioksidan maupun imun booster. Berdasarkan studi literatur yang telah dilakukan, beberapa tanaman lokal Indonesia diprediksi dapat menjadi kandidat penghambat COVID-19. Tanaman yang memiliki potensi sebagai antiviral yang dapat menghambat COVID-19 antara lain: jahe merah (Zingiber officinale), kunyit (Curcuma longa L.), temulawak (Curcuma xanthorriza Roxb), teh hijau (Camelia sinensis), meniran (Phyllantus niruri L.), salam (Syzygium polyanthum), jambu biji (Psidium guajava), cengkeh (Sygizium aromaticum), dan bawang putih (Allium Sativum). COVID-19 (Corona Virus Disease of 2019) is one of disease infecting human respiratory system. This pandemic spreads out not only in Indonesia, but also in all countries around the world. In nowdays, COVID-19 become a terrible disease because the virus can infect very fast through human to human transmission and there is no clinically published vaccine against the SARS-CoV-2 virus to prevent the transmission. One of prevention methods of COVID-19 is by enhancing immune system. Consuming of some food which contain antioxidant agent or immune booster is known as one of method to enhance the immune system. Based on literature studies, there are some Indonesian local plants predicted as the inhibitor against COVID-19. Those plants which are potential as the antiviral to inhibit COVID-19 including red ginger (Zingiber officinale), turmeric (Curcuma longa L.), temulawak (Curcuma xanthorriza Roxb), green tea (Camelia sinensis), meniran (Phyllantus niruri L.), salam (Syzygium polyanthum), guava (Psidium guajava), clove (Sygizium aromaticum), dan garlic (Allium Sativum).Keywords: COVID-19, SARS-CoV-2, medicinal plants, antiviral
Perceived Stress, Depression and Alcohol Use Disorders in College Students During the COVID-19 Pandemic: A Socio-Economic Dimension
Authors: Gavurova Beata , Ivankova Viera , Rigelsky Martin
Published: November 2020

The objective of the study was to examine the effects of perceived stress on depression and subsequently to examine the effects of depression on alcohol use disorders. The data were obtained by an electronic questionnaire survey during the coronavirus disease 2019 (COVID-19) pandemic (n=1523 Slovak college students). Descriptive, regression and correlation analysis were used in the analytical processing, while the analyses included students' scores in three diagnostic tools (Perceived Stress Scale (PSS), Patient Health Questionnaire for depression (PHQ 9) and Alcohol Use Disorders Identification Test (AUDIT)), as well as gender and income characteristics. The PSS identified an increased level of perceived stress in female students, in contrast, the AUDIT showed an increased level of alcohol use disorders in male students. Differences in mental and behavioural disorders between the gender and income categories were significant in most of the analysed cases. In terms of gender-income characteristics, it was possible to confirm a significant positive effect of the PSS score on the PHQ 9 score, as well as a significant positive effect of the PHQ 9 score on the AUDIT score. As a result, efforts to reduce stress will be reflected in a reduction of depressive disorders as well as a reduction of excessive alcohol consumption among students.
mySORT: A Web Framework by using Deconvolution Approach to Estimating Immune Cell Composition from Complex Tissues
Authors: Chen Shu-Hwa , Yu Bo-Yi , Kuo Wen-Yu , Lin Ya-Bo , Su Sheng-Yao , Lu I-Hsuan , Lin Chung-Yen
Published: November 2020

Cancer immunotherapy reaches a remarkable achievement in various cancer types and brings new possibilities to improve cancer patients’ long-term survival. However, outcomes vary from case to case, and the present protocol benefits a small fraction of patients. One notable factor is the tumor microenvironment, especially the immune cell components, that may reflect the immune response's status quo on site. Thus, understanding the content of infiltrating immune cells in tumors is not only for research interesting but also a crucial subject toward precision medicine. We implement an algorithm for resolving relative proportions of twenty-one immune cell subclasses from a human tissue profiled transcriptome by microarray technology to reach the goal above. By selecting gene features and then adopting ?-Support Vector Regression, we can construct a deconvolution model and resolve the immune cell context. The excellent consistency between the estimated values and the correct immune-cell composition further demonstrates this approach provides a more natural alternative to revealing samples' immune cell content and reliable results like recent single-cell technologies. Based on this algorithm, the web-based deconvolution tool implemented named mySORT provides a user-friendly interface for estimating the immune cell content by uploading gene expression profiling. We also present comprehensive visualization 2D/3D plots in mySORT so that users can easily make a comparison between different samples. Finally, we synthesized pseudo-bulk expression data from single-cell transcriptomic datasets of 17 melanoma and 16 head and neck cancer patients. The deconvolution results of microarray-based data in the previous study and synthetic pseudo-bulk data all proved the excellent performance of mySORT. We believe that mySORT can help researchers in all fields easily understand complex immune microenvironment. The website of mySORT is freely accessible on https://symbiosis.iis.sinica.edu.tw/mySORT/.
Personalised Therapeutic and Dietary Interventions as an Alternative Non-Invasive Management of Temporal Lobe Epilepsy
Authors: Garg Elika , Koche Sandhya , Mehdi Saher
Published: November 2020

A 12 year old boy was diagnosed with temporal lobe epilepsy (TLE) along with mesial temporal sclerosis based on MRI (magnetic resonance imaging) results. The diagnosis was further confirmed by genetic analysis. He also had minor psychiatric symptoms of obsessive-compulsive disorders and mood swings. After 4 years of treatment with Sodium Valproate no change in symptoms was observed. Genetic testing along with deep phenotyping revealed altered glutamate pathway and metabolism. Post genetic testing the patient was put on a combination of Sodium Valproate and Valproic acid along with supplementation of N-acetylcysteine (NAC), Cyanocobalamin, Pyridoxine and Cholecalciferol. Within three months of this combined therapy the patient experienced complete elimination of seizures and drastic improvement in mood and social behaviour. The case report highlights the importance of precision diagnosis in understanding the underlying perturbed pathways in structural epilepsy like TLE and demonstrates the importance of non-invasive targeted therapy in such cases.
Self Incompatibility, Inbreeding Depression, and Potential to Develop Inbred Lines in Alfalfa: A Review
Authors: Parajuli Atit , Yu Longxi , Peel Michael , See Deven , Wagner Steven , Norberg Steven , Zhang Zhiwu
Published: November 2020

Alfalfa (Medicago sativa L.) is a perennial, outcrossing legume crop predominantly grown for hay, silage, or pasture. Intensive selection has resulted in dramatic improvement in fitness traits, including winter survival and disease resistance. However, there has been minimal improvement in other economically important traits, such as hay yield, which is still comparable to 30 years ago. Intensive phenotyping costs on this type of trait hinder high selection pressure to identify superior outcross individuals. Severe inbreeding depression inhibits the development of inbred lines with accumulated favorable alleles that exhibit heterosis. This review highlights the outcomes of inbreeding depression as well as the causes, including unmasking deleterious alleles and triggering self-incompatibility. We tracked the research efforts that unveil the genetic bases underlying deleterious alleles and self-incompatibility. The magnitudes of inbreeding depression were compared with the rate of heterozygous halved time in diploid and tetraploid organisms. To fill in the gaps between the controversy and existing hypotheses, we theorized a dosage dominant model of inheritance. The dosage dominant model is similar to the Mendelian dominance model, in which a genotype exhibits a dominant phenotype if there is a dominant allele (alphabet dominant). The difference is that in the dosage dominant model, a genotype will result in a dominant phenotype if the number of dominant alleles is equal to or greater than the number of recessive alleles. This review also includes a discussion on the development of pseudo inbreds and a hypothesis to identify deleterious alleles using bulked segregant analysis and consequently to purge deleterious alleles using marker-assisted selection, to progress toward the successful development of pure inbred lines in alfalfa.
The Prevalence and Correlates of Substance Use Disorders Among Patients of Two Different Treatment Settings in Thailand
Authors: Pengpid Supa , Peltzer Karl
Published: November 2020

Background: Monk healers provide an accessible and popular service in Southeast Asia, but little is known on the substance use status of their clients. This investigation intended to assess and compare the rate and correlates of substance use disorders in two different treatment settings (monk healers=MH and primary health care=PHC) in Thailand. Methods: In a cross-sectional study, 1024 patients (591 of MH and 613 of PHC) responded to screening measures of the “World Health Organization Alcohol, Smoking, and Substance Involvement Screening Test Lite”, and two common mental disorders (major depression and generalized anxiety disorder) from November 2018 to February 2019. Logistic regression was used to estimate the determinants of any substance use disorder in the MH and PHC setting. Results: The prevalence of substance use disorder was higher in MH clients than PHC patients: any substance use disorder 11.7% (95% Confidence Interval-CI: 9.3%-14.5%) vs 5.4% (95% CI: 3.9%-7.5%), tobacco use disorder 7.6% (95% CI: 5.7%-9.9%) vs 2.5% (95% CI: 1.5%-4.0%), alcohol use disorder 10.0% (95% CI: 8.4%-13.6%) vs 4.3% (95% CI: 3.0%-6.3%), any drug use disorder 4.2% (95% CI: 2.8%-6.1%) vs 0.3% (95% CI: 0.08%-1.3%), and any past three months drug use 8.2% (95% CI: 6.2%-10.7%) vs 1.5%, 95% CI: 0.8%-2.8%). In adjusted logistic regression analysis, among MH clients, male sex (Adjusted Odds Ratio-AOR: 9.52, 95% Confidence Interval-CI: 5.06-17.92) was positively, and were married (AOR: 0.32, 95% CI: 0.16-0.61) and high social support (AOR: 0.40, 95% CI: 0.16-0.99) were negatively associated with any substance use disorder. Among PHC patients, male sex (AOR: 7.05, 95% CI: 2.99-16.63) was positively and age (AOR: 0.95, 95% CI: 0.92-0.98) was negatively associated with any substance use disorder. Conclusion: The proportion of substance use disorders among MH attendees was more than twice that of PHC attenders in Thailand, calling for collaboration in controlling substance use disorders between the two treatment systems.
Моделирование задач магнитной гидродинамики на высокопроизводительных вычислительных системах
Authors: Четверушкин Борис Николаевич , Chetverushkin Boris Nikolaevich , Савельев Андрей В , Saveliev Andrei V , Савельев Валерий Иванович , Savel'ev Valerii Ivanovich
Published: November 2020

Обсуждается алгоритм решения задач магнитной газовой динамики, который хорошо адаптируется на архитектуру вычислительных систем с экстрамассивным параллелизмом. В основе алгоритма лежит кинетическая модель, описывающая динамику ансамбля нейтральных и заряженных частиц, а также магнитного поля. В качестве иллюстрации приводятся результаты 3D-расчета динамики проводящей несжимаемой жидкости (расплавленного натрия) в канале, сопряженном с каверной.
Разностная схема с анализатором симметрии для уравнений магнитной гидродинамики
Authors: Устюгова Галина Валентиновна , Ustyugova Galina Valentinovna , Колдоба Александр Васильевич , Koldoba Aleksandr Vasil'evich
Published: November 2020

В работе предлагается вычислительный алгоритм для численного моделирования
двумерных МГД-течений, использующий анализатор симметрии в качестве элемента численного метода. Алгоритм основан на конечнообъемной схеме годуновского типа с приближенным решением задачи Римана для расчета потоков. Используется полярная сетка, но аппроксимация уравнений импульса и магнитной индукции проводится в декартовой системе координат. Предполагается, что течения либо преимущественно однородные плоскосимметричные, либо преимущественно
осесимметричные относительно оси сетки. Для реконструкции векторных переменных в расчетных ячейках используется анализатор симметрии, позволяющий локально отнести течение к одному из указанных типов. В зависимости от того, к какому типу будет отнесено векторное поле, для его реконструкции используются
соответствующие компоненты.
Webquest’s e ensino: uma experiência tocantinense para aprendizagem de História
Authors: Almeida Moura Antonio Guanacuy , Vas Braz Batista
Published: November 2020

Este artigo apresenta os resultados da aplicação da metodologia educacional WebQuest, metodologia colaborativa de pesquisa orientada na internet e amparada em recursos tecnológicos digitais, aqui aplicada no processo de ensino-aprendizagem em História. Para tanto, foi necessário refletir se o uso do WebQuest pode contribuir com a aprendizagem histórica dos alunos que a utilizam. A investigação deu-se através de pesquisa de campo, de natureza descritiva-exploratória, com alunos de uma turma de uma escola da rede federal de ensino situada na cidade de Dianópolis, na região sudeste do Estado do Tocantins. Os dados obtidos indicam algumas limitações relacionadas ao uso pedagógico de tecnologias digitais no espaço escolar, todavia, o uso da metodologia Webquest aplicada ao ensino de História pode favorecer a aprendizagem colaborativa entre os alunos e facilitar o acesso a fontes diversas por meio da pesquisa orientada na internet.
Conhecimento escolar sobre a Guerra do Paraguai: construção de significados e identidades, no Brasil e no Paraguai, no século XXI
Authors: Salles André Mendes , Neto José Batista
Published: November 2020

Buscou-se refletir a respeito de narrativas escolares sobre a Guerra do Paraguai e sua relação na construção de significados e identidades no contexto de ensino e aprendizagem, no Brasil e no Paraguai. O percurso metodológico contemplou a aplicação de questionários, a realização de entrevistas semiestruturadas com professores de História da educação básica de ambos os países e a análise dos livros didáticos por eles adotados. A análise dos dados revelou que o conhecimento escolar Guerra do Paraguai tem se constituído estratégico e privilegiado em relação à construção de identidades nacionais dos países envolvidos, bem como tem sido problematizado, atualmente, possibilitando uma reflexão em torno da valorização de um entendimento regional, de modo que conflitos da magnitude da Guerra do Paraguai não tornem a acontecer na região. Palavras-chave: Conhecimento Histórico Escolar. Guerra do Paraguai. Construção de identidades.
Ensino de História e o direito à vida
Authors: Ribeiro Renilson Rosa
Published: November 2020

Editorial
Narrativas, Direitos Humanos e Formação de Professores de História
Authors: Venera Raquel ALS , Da Silva Felipe Rodrigues
Published: November 2020

Apresentação
Long-term stability and efficacy of historic activated carbon (AC) deployments at diverse freshwater and marine remediation sites
Authors: Bridges Todd , Newell Sandra , Kennedy Alan , Moore David , Ghosh Upal , Needham Trevor , Xia Huan , Kim Kibeum , Menzie Charles , Kulacki Konrad
Published: November 2020

A number of sites around the United States have used activated carbon (AC) amendments to remedy contaminated sediments. Variation in site-specific characteristics likely influences the long-term fate and efficacy of AC treatment. The long-term effectiveness of an AC amendment to sediment is largely unknown, as the field performance has not been monitored for more than three years. As a consequence, the focus of this research effort was to evaluate AC’s long-term (6–10 yr) performance. These assessments were performed at two pilot-scale demonstration sites, Grasse River, Massena, New York and Canal Creek, Aberdeen Proving Ground (APG), Aberdeen, Maryland, representing two distinct physical environments. Sediment core samples were collected after 6 and 10 years of remedy implementation at APG and Grasse River, respectively. Core samples were collected and sectioned to determine the current vertical distribution and persistence of AC in the field. The concentration profile of polychlorinated biphenyls (PCBs) in sediment pore water with depth was measured using passive sampling. Sediment samples from the untreated and AC-treated zones were also assessed for bioaccumulation in benthic organisms. The data collected enabled comparison of AC distribution, PCB concentrations, and bioaccumulation measured over the short- and long-term (months to years).
In Situ Silver-based Electrochemical Bioreactor In Vivo
Authors: Huang Yong , Zhong Liping , Deng Zhiming , Wu Pan , He Jian , Bai Zhihao , Zhong Yi , Peng Hongmei Hongmei , Zhang Kun , Liang Xing-Jie , Zhao Yongxiang
Published: November 2020

In this study we show for the first time that a reduced graphene oxide (rGO) carrier has a 15-fold higher catalysis rate than graphene oxide (GO) in Ag+ reduction. Based on this, we constructed a tumor microenvironment-enabled in situ silver-based electrochemical oncolytic bioreactor (SEOB) which unlocked an Ag+ prodrug to generate silver nanoparticles and inhibited the growth of various tumors. In this bioreactor system, intratumoral H2O2 acted as the reductant and the rGO carrier acted as the catalyst. Chelation of aptamers to this prodrug increased the production of silver nanoparticles by tumor cells, especially in the presence of Vitamin C, which broke down in tumor cells to supply massive amounts of H2O2. Consequently, highly efficient silver nanoparticle-induced apoptosis was observed in HepG2 and A549 cells in vitro and in HepG2- and A549-derived tumors in vivo. The apoptosis was associated with ROS-induced changes in mitochondrial membrane potential and DNA damage. The specific aptamer targeting and intratumoral silver nanoparticle production guaranteed excellent biosafety, with no damage to normal cells, because the Ag+ prodrug was specifically unlocked in tumors. More significantly, there was no evident tissue damage in monkeys, which greatly increases the clinical translation potential of the SEOB system.
Prevalence and presentation of patients with the chief complaint “cardiac arrhythmia” – data from a large university emergency department
Authors: Novotny Julia , Klein Matthias , Thienel Manuela , Fichtner Stephanie
Published: November 2020

Background Cardiac arrhythmias (CA) are a common chief complaint that leads to presentation at the emergency department (ED). However, data on the underlying diagnoses in patients with CA is not well studied. Our objective was to analyse the prevalence and clinical presentation of CA in the setting of an interdisciplinary ED.Methods In this retrospective study, we included all patients admitted to our ED in the Ludwig-Maximilian University Hospital in Munich within one year with the chief complaint “cardiac arrhythmia”. Subsequently cardiac rhythm in the 12-lead electrocardiogram (ECG), clinical presentation, therapy performed in the ED and in-hospital care were analyzed.Results A total of 558 out of 36.798 visitors of the ED presented with the chief complaint of CA. 42.3% of these patients indeed showed a pathologic heart rhythm on the initial ECG. The most abundant pathological ECG diagnosis was atrial fibrillation. In the pathological ECG group 60.6% and in the sinus rhythm (SR) group 39.4% of patients had to be admitted to hospital, and 34.7% with pathological ECG underwent invasive investigations (16.8% in the SR group). Conclusion Over half of our patients showed no arrhythmia on the ED ECG. The most abundant arrhythmia was atrial fibrillation. Most of the patients were stable. However, with 49.5% admission rate was quite high. This fact illustrates the need for better outpatient management of these patients. Further chief complaint CA in the ED must not be mistaken as disease specific.
Digital Citizenship zwischen Datafizierung und Performativität
Authors: Dander Valentin
Published: November 2020

Rezension zu:

Hintz, Arne, Lina Dencik, und Karin Wahl-Jorgensen. 2019. Digital citizenship in a datafied society. Cambridge, UK ; Medford, MA: Polity Press.