bluuebunny/crossref_metadata_2025 huggingface dataset:
Hematological, biochemical, and hormonal effects of organochlorine pesticide residues found in canal and tap waters on albino white rats
Authors: Moustafa Abdellatif Abbassy  , Moustafa Abdelalieam, Khalifa  , Omar Al-Sayed. Omar  , Eman Nour. El-Deen
Published: November 2023

Analysis of water from the canal that feeds the Damanhour water station and tap water in Damanhour, Beheira Governorate, Egypt, revealed the presence of gamma-HCH, beta-HCH, heptachlor epoxide, p, p D.D.E., dieldrin, endrin aldehyde, endosulfan sulfate, and endrin ketone. Therefore, this study aimed to investigate the adverse effects of administration of the OCl pesticide residues found in canal water (0.0448 µg/ kg b. wt.) and tap water (0.022 µg/ kg b. wt.) to white Albino rats. Results revealed that treatment of male and female rats with a single oral dose of OCl pesticide residues found in both canal and tap water caused slight alteration in Hemoglobin (Hb), red blood cells (RBC) in male rats, and packed cell volume (PCV) in male and female treated rats relative to control. There was a significant increase in Hb, a decrease in RBC counts in treated female rats, and a significant decrease in WBC count in both male and female rats. There was a slight alteration in GOT, GPT, and G.GT activity in both male and female rats and a significant increase in alkaline phosphatase (ALP) activity in male rats. Compared to controls, treated rats had substantial increases in uric acid and albumin concentrations and a slight alteration in total protein concentration in the serum. Administration of OCl residues to rats caused no significant effect on male or female progesterone. It caused a significant increase in testosterone concentration in treated female rats and a decrease in the serum of male rats. Compared to controls, treated male rats had slightly lower follicle stimulation hormone (FSH) levels, and treated female rats had higher levels. Also, no significant difference was observed in T4 levels between the control and treated females in treated rats. However, the T4 level increased significantly in the males administered the high O.C.s found in canal water. T3 levels decreased in the serum of male and female rats, but T3 was significantly reduced in male rats given an oral dose of OCl residues in canal water. Unlike their effects on T3 levels, the impact of OCl residues on T4 levels in this study was inconsistent in treated rats. Conclusions: Administration of a single oral dose of OCl pesticide residues found in both canal and tap water to rats caused significant and non-significant alteration in some hematological, biochemical, and hormonal biomarkers in the serum of treated rats compared to control.
Computational exploration of the significance of COPS6 in cancer: Functional and clinical relevance across tumor types
Authors: Wang Shi-Lin , Zhuo Guang-Zheng , Wang Li-Ping , Jiang Xiang-Hu , Liu Guo-Hong , Pan Yun-Bao , Li Yi-Rong
Published: November 2023

BACKGROUND

The COP9 signalosome subunit 6 (COPS6 ) has been implicated in cancer progression, while its precise role in most types of cancer remains elusive.

AIM

To investigate the functional and clinical relevance of COPS6 across various tumor types using publicly available databases.

METHODS

We used R software and online analysis databases to analyze the differential expression, prognosis, mutation and related functions of COPS6 in pan-cancer.

RESULTS

Differential expression analysis and survival analysis demonstrated that COPS6 was highly expressed and associated with high-risk profiles in the majority of cancer types. Possible associations between COPS6 expression level and prognostic outcomes were found using data from public databases. Mutational analysis revealed that missense mutations were the predominant type of COPS6 mutation. Additionally, positive correlations were identified between COPS6 expression level and tumor mutational burden and microsatellite instability in most types of cancer. Immune infiltration analysis demonstrated a negative correlation between COPS6 expression level and CD8+ T cell infiltration in certain types of cancer. The correlation between COPS6 expression level and cancer-associated fibroblast infiltration exhibited heterogeneity, in which a positive correlation was found in head and neck squamous cell carcinoma and tenosynovial giant cell tumor, and a negative correlation was identified in diffuse large B-cell lymphoma and thymoma. The correlation between COPS6 expression level and macrophage infiltration was closely related to macrophage type. Gene co-expression and enrichment analysis highlighted transcription elongation factor B polypeptide 2 and G protein pathway suppressor 1 were significantly and positively associated with COPS6 expression level. These genes were predominantly involved in processes, such as ubiquitin-mediated proteolysis and human immunodeficiency virus 1 infection.

CONCLUSION

In conclusion, this study systematically explored the significance of COPS6 across different tumor types, providing a solid foundation for considering COPS6 as a novel biomarker in cancer research.
Bibliometric analysis of the global research status and trends of mechanotransduction in cancer
Authors: Zhang Yi-Zhan , Li Meng-Zhu , Wang Guang-Xin , Wang Da-Wei
Published: November 2023

BACKGROUND

The development of cancer is thought to involve the dynamic crosstalk between the tumor cells and the microenvironment they inhabit. Such crosstalk is thought to involve mechanotransduction, a process whereby the cells sense mechanical cues such as stiffness, and translate these into biochemical signals, which have an impact on the subsequent cellular activities. Bibliometric analysis is a statistical method that involves investigating different aspects (including authors’ names and affiliations, article keywords, journals and citations) of large volumes of literature. Despite an increase in mechanotransduction-related research in recent years, there are currently no bibliometric studies that describe the global status and trends of mechanotransduction-related research in the cancer field.

AIM

To investigate the global research status and trends of mechanotransduction in cancer from a bibliometric viewpoint.

METHODS

Literature on mechanotransduction in cancer published from January 1, 1900 to December 31, 2022 was retrieved from the Web of Science Core Collection. Excel and GraphPad software carried out the statistical analysis of the relevant author, journal, organization, and country information. The co-authorship, keyword co-occurrence, and keyword burst analysis were visualized with VOSviewer and CiteSpace.

RESULTS

Of 597 publications from 745 institutions in 45 countries were published in 268 journals with 35510 citation times. With 270 articles, the United States is a well-established global leader in this field, and the University of California system, the most productive (n = 36) and influential institution (n = 4705 citations), is the most highly active in collaborating with other organizations. Cancers was the most frequent publisher with the highest H-index. The most productive researcher was Valerie M. Weaver, with 10 publications. The combined analysis of concurrent and burst keywords revealed that the future research hotspots of mechanotransduction in cancer were related to the plasma membrane, autophagy, piezo1/2, heterogeneity, cancer diagnosis, and post-transcriptional modifications.

CONCLUSION

Mechanotransduction-related cancer research remains a hot topic. The United States is in the leading position of global research on mechano-oncology after almost 30 years of investigations. Research group cooperations exist but remain largely domestic, lacking cross-national communications. The next big topic in this field is to explore how the plasma membrane and its localized mechanosensor can transduce mechanical force through post-transcriptional modifications and thereby participate in cellular activity regulations and cancer development.
公私協力的實踐-準公共幼兒園政策的影響與反思
Authors: 林俊瑩 林俊瑩
Published: November 2023

為因應少子女化，我國於2018年開始實施少子化對策計畫，並以擴展平價教保服務及減輕家長負擔為政策重點，而準公共幼兒園為當中相當重要的政策工具。該政策目標除了要讓家長免於負擔沉重托育與教育費用之壓力，並擴展平價教保服務，更有確保教保品質的意圖。不過該政策效果如何？目前成果相當有限。因此，本研究以地方政府主管科人員、巡輔員、幼兒園主管與教保服務人員為對象，運用訪談進行文本資料的蒐集與探究。研究顯示準公共幼兒園政策使整體教保服務提供的量能明顯擴增，價格平實，可充分滿足家庭需求，教保服務人員待遇有被合理保障，也對減緩師資流動稍具效果。惟此政策仍有侷限，包括部份私幼業者仍對該政策的信任不足而影響參與意願；而管控與評鑑標準略為於寬鬆，教保品質也就良莠不齊；或是經營者理念不夠正派，教保服務人員對專業成長的配合度不高，教學補助未必善用於品質提升；最後，中央推動此政策，但所需經費由地方政府部份買單，或是要求地方政府在時限內達成一定績效，都讓地方政府承受不小的壓力。

 

A low national fertility rate brings various challenges to society, and many policies promoted by the Taiwan government in the past 20 years have focused on how to solve related social problems caused by declining rates. In response to the country’s low birth rate, Taiwan began to implement a plan of countermeasures for it since 2018. Among the policies focused on expanding affordable care and education services and reducing parental burdens, quasi-public preschools are one of the important policy tools. In addition to alleviating parents from the burden of heavy childcare and education costs and expanding affordable care and education services, this policy also aims to ensure the quality of care and education. However, the policy has so far achieved limited results. Therefore, this study conducted data collection and exploration by interviewing local government officials responsible for this area, auxiliary patrol officers, preschool supervisors, and care and education service personnel. The findings show that the quasi-public preschool policy could significantly expand the capacity of the overall care and education services at reasonable prices, which could fully meet the needs of families. A reasonable guarantee for the remuneration of care and education service personnel also has a slight effect on slowing down the turnover of teachers. However, this policy still has some limitations. Some private preschool practitioners still have insufficient trust in this policy. Moreover, slightly lax control and evaluation standards have led to the uneven quality of care and education. If the operators have bad faith and the care and education service personnel show low coordination willingness in their professional growth, then the teaching subsidies may not be used in quality improvement. Finally, while the central government has promoted this policy, local governments have been under great pressure to locate financial sources to pay for it in part or to achieve certain performance goals within a limited time frame.

 
COVID-19 新冠肺炎輕度確診者之心理反應與韌性之 因應：從預防教育觀點出發
Authors: 林烝增 林烝增 , 連廷嘉 連廷嘉 , 涂喜敏 涂喜敏
Published: November 2023

本研究旨在探討輕度確診者之心理反應，並了解其心理韌性之因應。本研究在2022年台灣疫情甫剛擴散，民眾對於染疫抱持不同心情，本研究從關懷民眾身心健康，以及預防教育地觀點下，採用質性研究方法，邀請願意參與研究4位研究對象，進行半結構訪談，將訪談結果予以分析整理。COVID-19輕度患者在確診後的反應有9類：害怕污名不想聲張、懷疑困惑、驚訝與驚慌、否認、擔心、被指責的無奈、內疚、接受、躬逢其盛地跟上流行等。其發揮心理韌性所使用的積極因應有三大類：第一是個人因素：坦誠面對、設定目標與堅持決心。第二資源因素包括：家庭韌性、社會支持、數位能力等重要資源，第三是正面思考力：避免過多思考與訊息、感恩心、保持幽默、平常心、重新框架、獨處能力、保持彈性等7種因應方式。本研究分析輕症確診者的心理反應與韌性的因素，有助於民眾在後疫情時代更加了解常見的情緒反應，有助於個人心理適應，並進一步採用積極因應方式，促進全民疫情下的心理韌性與身心健康。

 

This study aims to explore the psychological responses of mildly confirmed COVID-19 patients and understand their coping mechanisms in terms of psychological resilience. Conducted in Taiwan in 2022, when the epidemic was initially spreading, this research takes a perspective that emphasizes caring for the mental and physical well-being of individuals and preventive education. A qualitative research approach was employed, and four participants who were willing to take part in the study were invited for semi-structured interviews. The interview results were analyzed and organized for further examination. Result: Nine (9) marked responses of people diagnosed with mild COVID-19 condition are: fear of stigmatization; suspicion and confusion; shock and panic; denial; concern; helplessness of blame; guilt; acceptance; being fashionable. Their adaptation and resilience coping with the condition manifest in three domains: First—Personal factor: radical acceptance and determination to get through challenges; Second—Resource factor: critical resources such as family resilience, societal support, and digital competency; Third—Positive Thinking factor: seven (7) coping competency: avoiding rumination and information overload; gratitude; humor; serenity; reframing; comfort in being alone.

 
The Chinese Character as an Interface for Artistic Creation: Re-Cognition of Graphics and Phonetics
Authors: Gong Haomin
Published: November 2023

This article examines two modern artistic explorations of the Chinese character. It takes Xu Bing’s Square Word Calligraphy and Jonathan Stalling’s Sinophonic English Poetry as examples and investigate how contemporary art reimagines and reconstructs the “potential” of Chinese characters and what ideological and political implications these processes may have for transcultural communication in today’s world. Situating the production of both works in Xu’s and Stalling’s respective creative experiences and larger sociocultural conditions, this article shows how both works, which deploy the graphics and the phonetics of the Chinese character as interfaces, engage in the politics of transcultural art creation and communication, and achieve their generative effects. Through this investigation, it hopes to illuminate the critical power of the Chinese character used as an interface in challenging linguistic, ideological, and cultural “norms” and questioning racial, national, and political prejudice.
A comprehensive network pharmacology study of Nelumbinis semen (Lotus Seeds) phytochemicals for Atherosclerosis and Type 2 Diabetes Mellitus
Authors: Bhupathie Dhansri , M Sathish Kumar , Rengasamy Kannan RR
Published: November 2023

Cardiovascular death remains the top causes of death, and one of the main risk factors associated with cardiovascular diseases are Atherosclerosis and Type 2 Diabetes Mellitus. The associated conspiracy was high because of the failure of the complete regulatory network rather than a single gene or protein malfunction, so one-target one drug fails for complete eradication of the disease. Natural compounds had the potency to act upon various targets to elucidate complete therapeutic effects. In traditional medicines, Nelumbinis semen or lotus seeds were used in treating multiple diseases and as a functional food. In the world of drug discovery, the idea of creating multi-target medications against complicated conditions is gaining momentum. To understand the mechanism emphasized by the therapeutic effect of Nelumbinis semen or lotus seeds, which act upon various targets and elucidate cumulative activity in Atherosclerosis and Type 2 Diabetes Mellitus. The bioactive components and their targets were obtained, and common targets associated with atherosclerosis and type 2 diabetes mellitus were taken. The network was constructed using Cytoscape 3.9.1 software. The protein-protein interaction was analysed using the STRING database. Gene and pathway enrichment was performed using ShinyGo 0.77 software. The pathway associated with the diseases and no of genes involved were studied. The active compounds of the lotus seed are Myricetin, Quercetin, Isofucosterol, Rhamnetin, Myristic acid, etc. The main and active targets for lotus seeds were PPARα, INSR, HMGCR and NCp1L1. The key biological pathways by which the compound elucidates therapeutic effects are Diabetic cardiomyopathy and Terpenoid backbone biosynthesis.
The Open Access Week in the Scholarly Blogosphere
Authors: Pampel Heinz
Published: November 2023

Happy Birthday, Open Access! Last Sunday, the Berlin Declaration turned twenty years old (Pampel & Kindling, 2023). Its anniversary coincides with the international Open Access Week. During this action week, events promoting Open Access are organized worldwide (an overview can be found at openaccessweek.org.
Isolation of bacteria producing lipase from copra (Cocos nucifera l.) Cake for degradation of vegetable waste oils
Authors: Kavyaja Mouri Bethapudi  , Priya R. Iyer
Published: November 2023

Vegetable waste oil consists of long chain triglycerides (LCTs). Waste oil from the kitchen causes clogging of the pipe as they solidify while passing from the kitchen. The waste with oil in the garbage will be drained into the ground and then into ground water which will lead to pollution of the ground water. Lipase is an enzyme used to break down the triglycerides into free fatty acids and glycerol by catalyzing the hydrolysis of the ester bonds in triglycerides. Bacteria Lipase is isolated from copra (Cocos nucifera L.) cake. The isolated bacteria were identified by the biochemical characterization and was sequenced by 16sRNA. The lipase production by the bacteria was identified by tween 80. The enzyme activity was identified by titrimetric method. Enzyme was extracted by salting out method and was partially purified by the SDS – PAGE.
Financial management competence of school heads and performance of schools in Leyte division
Authors: Ernel S. Merano
Published: November 2023

The study investigates the financial management competence of elementary school heads and the performance of schools in Leyte Division. The research involved 70 school heads and 369 teachers involved in the School Financial Task Force for the 2016-2017 school year. The findings revealed that most school heads are middle-aged with low family income and lack training in school financial management. They manage various financial resources, with small enrollment and teacher populations. In terms of budgeting, accounting, procurement, and asset management, most school heads are competent, but few are less competent. Family income and number of trainings attended are related to asset management competence. The National Achievement Test results are average, and school performance is not related to the financial management competence of school heads. The study recommends that school heads attend training and seminars related to school financial management, involving school planning teams and community involvement. Effective management of school financial resources is crucial for financing all school activities.
Assessing the implications of killer herdsmen in the north and unknown gunmen in the south for the tourism industry in Nigeria
Authors:   Department of Political Science, Nnamdi Azikiwe University, Awka, Augustine Ejiofor Onyishi , J. Kelechi Ugwuanyi ,   Global Heritage Lab, University of Bonn, Germany,   Department of Archaeology and Tourism, University of Nigeria, Nsukka, Cyriacus Chijioke Oji ,   Department of Archaeology and Tourism, University of Nigeria, Nsukka
Published: November 2023

More than ever, the contemporary Nigerian social landscape is characterised by civil aggression and violent attacks by many (known and unknown) violent groups. The activities of these groups have created insecurity crises of unparalleled intensity in the country. This paper examined the implication of insecurity (or these violent attacks) for the tourism industry in Nigeria. The study used a desk research approach to generate secondary data following a time series design. It descriptively analysed the information using line graphs, bar charts and simple percentages, using the theory of ‘failed state’ as a framework for the interpretation and discussion. The study found a relationship between recurrent insecurity and prevailing challenges facing the tourism industry in Nigeria. Since ‘all crime is local’, it is recommended that the conventional approaches to solving the insecurity problems in Nigeria should be complemented with the help of members of local communities and mass media using state-of-the-art technology to expose criminals and ensure constant checks on local migrants, international emigrants and business people that deal in small arms and light weapons.
Developing a trilingual glossary for the physico-chemical properties of alternative sources of edible potash (culiash) from unripe plantain peelings (UPP)
Authors:   Department of Linguistics and Languages, Federal University,  Ndufu Alike, Ikwo, Ebonyi State, Nigeria, Nnenna Nwosu , Onyinye Anne Nwankwo ,   1Department of Linguistics and Languages, Federal University,  Ndufu Alike, Ikwo, Ebonyi State, Nigeria, Chinedu Ogbonnia Egwu ,   Department of Medical Biochemistry, Federal University,  Ndufu Alike, Ikwo, Ebonyi State, Nigeria
Published: November 2023

Due to the rising correlation between food additives and several health disorders, it is important that researchers in this area disseminate their findings to rural artisans, translators, indigenous newscasters and consumers. This will promote healthy living and consequently reduce health risks which may be associated with artificial food additives. However, this has been quite challenging in that it has been hampered by the lack of indigenous technical terms, especially in the Igbo language. Against this backdrop, this study develops a trilingual glossary for the physico-chemical properties of alternative sources of edible potash (UPP). The convenience sampling technique was employed in selecting twenty female participants who were not above 50 years of age from the Mbaise community, a town in Imo State of Nigeria. Personal interviews, observation/participation and documentation in the field were the primary sources of data collection, while the secondary sources included textbooks, journals, theses, dissertations, magazines, newspaper articles and the internet. The chemical compositions of the edible ash were ascertained using standard analytical methods. To generate its technical terms, four major linguistic principles (indigenisation, terminologisation, semantic shift, paraphrasing with explanation and compounding) were applied in developing equivalent terms in the Igbo language. Findings show that indigenisation and compounding are more productive in the development of terms in the Igbo language for the physico-chemical properties/constituents of alternative sources of edible potash than pure loaning. Terminographers are encouraged to standardise these developed terms while working to fill the gap of terminology scarcity in African languages.
Estudo do reaproveitamento de rejeitos de minério de ferro e carvão vegetal da microrregião do Baixo Pantanal através da produção de briquetes autorredutores
Authors: De Jesus Leandro Gustavo Mendes , Campos Janiele da Silva , De Araújo Matheus Heleno Cabriotte Vieira
Published: November 2023

O alto-forno é um reator metalúrgico que produz ferro gusa, uma liga de ferro com carbono. Na operação do reator gases redutores ascendem em contracorrente com o minério de ferro. Os rejeitos dos minérios de ferro da microrregião do Baixo Pantanal, embora possuam as características químicas desejáveis para o processo não possuem as características de distribuição granulométrica e resistência mecânica. Portanto, o objetivo do trabalho é verificar a viabilidade da utilização dos rejeitos de minério de ferro e carvão vegetal através da produção de briquetes autorredutores. Com isso, os processos de aglomeração surgem como alternativa promissora ao aproveitamento dos rejeitos de minérios de ferro. Para isso foram elaborados três briquetes que foram submetidos a ensaios de redução à temperatura de 1200 ˚C em diferentes tempos de ensaio (15, 30 e 45 minutos). Como resultado obteve-se a mesma morfologia de briquetes de outros autores e, a partir de ensaios indiretos, se obteve a porcentagem máxima de 92 % de produto reduzido, o que leva a crer que a utilização dos rejeitos de minério de ferro e carvão vegetal, além de ser possível, é uma alternativa promissora.
Analysis of COVID-19 Pandemic Waves in Death Figures of Turkey
Authors: Balaban Muzaffer
Published: November 2023

Introduction: The COVID-19 pandemic has resulted in a substantial number of deaths worldwide, making it crucial to conduct a periodical behavior analysis of the COVID-19 death figures. By understanding the trends and patterns in mortality rates, decision-makers can make informed choices on prioritization of interventions to pandemics.Method: Death figures due to COVID-19 between 17 March 2020 and 27 November 2022 were taken into account in this study. Mortality data were analyzed using statistical and graphical methods. Von Bertalanffy’s growth model parameters were estimated for each wave. Then the model performance measures were calculated.Discussion: In this study, the course and change of daily mortality data over time were examined. The data reveal that the COVID-19 pandemic occurred in Turkey as four waves. Von Bertalanffy’s growth model appears to be an explanatory model for all pandemic waves according to the performance measures.Conclusion: It was observed that the COVID-19 pandemic spread in Turkey in four waves. Investigating COVID-19 and similar pandemics using versatile and multidisciplinary methods is of great importance in understanding and predicting the behavior of pandemics.
Incidence and Perinatal Outcomes of Twin Pregnancy in Tertiary Healthcare Facility, Odisha, India
Authors: Shaw Sailabala , Behera Braja Kishore , Nayak Bikash Chandra , Mohapatra Gurukrushna
Published: November 2023

Background: Assisted reproductive technology has resulted in a progressive rise in the incidence of twin pregnancies, which affect both mother and child in terms of antepartum complications. Objective: To assess the perinatal outcomes of twin pregnancies and the influence of chorionicity on them in a tertiary healthcare facility. Methods: It is a hospital-based cross-sectional study that was carried out in the Obstetrics and Gynecology Department of S.C.B. Medical College Hospital, Cuttack, during the period from 2013 to 2015. All mothers having twin pregnancies (with 28 weeks of completed gestation) admitted to the antenatal (ANC) ward and labor room during this period were taken as a study group, and written informed consent was taken after explaining the details of the study. Results: A total of 150 cases are identified; among them, 98 cases (65.33%) are dichorionic diamniotic, 50 cases (33.33%) are monochorionic diamniotic, and 2 cases (1.33%) are monochorionic and monoamniotic pregnancies. The majority (66%) of the twin pregnancies were between 35-38 wks of gestational age at the onset of labor. It is also observed that macerated births, stillbirths, and neonatal deaths are higher in mono-chorionic twins as compared to dichorionic twins. Conclusions: Twin pregnancies carry a greater risk of adverse outcomes, especially perinatal mortality and neonatal morbidity, in monochorionic twins than dichorionic twins. Good antenatal care, early diagnosis of chorionicity, and antepartum assessment of placentation will prevent mortality and morbidity.
Exploring the Adverse Effects and Prevention Methods of Electronic Games on the Physical and Mental Development of Adolescents in Contemporary Society
Authors: Mak Yuanqi Denise
Published: November 2023

The electronic game industry has developed rapidly in the past decade. From Contra and Super Mario to League of Legends and Glory of Kings, players enthusiasm for games has been enduring. Among them, game consoles have brought arcade halls to peoples homes. With the development of the times, iPhones make games within reach with the level of realism in image technology has significantly improved. With the popularity of games, a problem has emerged which is game addiction. With the expansion of the base of game players, the problem of game addiction has become a social problem that cannot be ignored. Many studies have examined the risk effects of game addiction, including academic performance, physiological development, social development, and the formation of negative emotions such as package personality, anxiety, depression, and suicidal tendencies. This study has integrated these variables to explore the role of multiple influencing factors in developing game addiction and their potential prevention methods.
Analysis on the Reasons for the Failure of Revolutions: A Comparison Between the American Revolutionary War and the American Civil War
Authors: Cong Jianwen
Published: November 2023

The American Revolutionary War aimed for political equality, resulting in the independence of the United States and the retention of the social order. The law established after the movement preserved slavery without making a direct claim. In contrast, the target of the American Civil War was to abolish slavery. It gained legal success but failed to change American society. Treating citizens differently according to their skin colour was banned, however, racial segregation remained in the country. In this paper, the causes of the failure of the two revolutions mentioned above are discussed, focusing on their influences on laws and communities. The principles, aims, and results of the events are compared and contrasted, so as to discover the reasons why revolutions are not able to shape society according to their purposes. Conclusions can be drawn that revolutions do not succeed mainly due to two reasons: either because the laws that line up with the principles of the revolutions are not established as the revolutions themselves do not aim for the principles or because the principles are not carried out in society even if related laws are established, for the domestic force against them is too strong.
Relationship Between Judicial Decisions and the Pursuit of Peace and Justice in International Law
Authors: Su Jiayi
Published: November 2023

The issue of potential tensions between justice and peace has arisen in the context of the growth of institutions for international justice. It is easy to find details from Columbia, Uganda, South Africa, and so forth. It is an old controversial debate, in fact, which focuses on whether perpetrators should be given punishment or amnesty in the aftermath of war and how society emerging from political violence successfully and peacefully achieves post-conflict reconstruction. In fact, the international community has offered various strategies as a transitional mechanism that reflected peace and justice in different ways. However, there are still lots of problems. This article introduces and analyzes these problems behind them. This paper involved some reviews from the victims and dozens of records and data to reflect the situation. This paper aims to recognize the value of peace and justice by comparing three examples.
The Research on the Influence of the Life of Children with Attention Deficit Hyperactivity Disorder Coexisting with Anxiety Disorders
Authors: Lu Yi
Published: November 2023

Attention deficit hyperactivity disorder and anxiety are two mental disorders that enable children to behave badly in daily life and be poor at learning. And most importantly, anxiety is associated with a high probability of attention deficit hyperactivity disorder. The paper explores the specific problems faced by children with attention deficit hyperactivity disorder and anxiety in learning and daily life and how to help them correct to the level of ordinary people to the greatest extent. The first experiment which examined behavioral problems and self-awareness characteristics of children with both anxiety and through the methods of using the two-stage epidemiological investigation and filling out the behavioral survey scale. The survey surveyed 9,495 teenagers and children from Hunan Province. The Achenbach Child Behavior Scale and the Piers-Harris Child Self-awareness Scale are two scales that were applied during this experiment. The second experiment involved the following experiments: the alphanumeric connection task, stroop color word naming, and the Rey complex graphic memory. The purpose of this experiment is to examine the executive function of children with comorbidity. The paper illustrates that all the symptoms of general attention deficit hyperactivity disorder will reflect the life of children with attention deficit hyperactivity disorder co-existing with anxiety disorders and some diseases can be more severe.
Research on the Exercise Prescription to Reduce the Health Problems of the Elderly Caused by Social Environment in China
Authors: De Yining
Published: November 2023

Combining the current situation of Chinas social structure and the health condition of the elderly, using scientific methods to point out the application methods and scope of exercise prescription. What kind of health problems Chinese society brings to the elderly, and how these health problems should be solved by exercise prescription? This includes customized exercise prescriptions based on region, condition, health status, medical history, family environment, age, and gender. A census of health conditions was conducted using a large body of public health literature, which was then combined with physiological and psychological scholarly articles to develop a matched treatment program using the concept of exercise prescription. Chinese older adults need to be provided with individualized and tailored exercise prescription programs based on region, economic conditions, health status, medical history, family environment, age, and gender.
A Comparative Study on the Background of the Formation of Shadow Education Between China and Singapore Exploring the Perspective of Historical Factor Analysis
Authors: Zhou Yuxin
Published: November 2023

Nowadays, shadow education is popular worldwide, especially in East Asian countries. This paid form of extracurricular education aligns with mainstream educations teaching objectives, content, methods, and means. This article selects China and Singapore as the research subjects, influenced by Confucian culture and exam-oriented education. The prosperous background of shadow education has many similarities. The focus of this study is to use the historical factor analysis method to perspective the economic, cultural, and educational backgrounds from a historical perspective, deeply explore the underlying reasons and impacts, and aspire to explore the similarities and differences in the background of the formation of shadow education between the two countries. At the same time, the author is reflecting on the current educational situation and policies reflected in the shadow of education, reflecting on the loopholes in mainstream education, and seeking reasonable countermeasures to promote the healthy development of mainstream education and the diversified development of various educational models.
Single Acute Toxicity Test of Eight Pollutants in Reclaimed Water to Q67
Authors: Dai Yilun , Zhang Jinyang
Published: November 2023

Human development and water resources are inseparable, there is no shortage of water resources in the world, but there is a total amount of abundant, can directly use fresh water scarce. At the same time, the distribution of water resources in space and time is not uniform, and different regions have different development degrees and different utilization degrees of water resources.
Analysis of the Current Situation of Medium and Low Yield Fields in China
Authors: Zhang Jing , Li Yanan
Published: November 2023

The area of medium to low yield farmland in China is huge and widely distributed. As a strategic reserve farmland resource, it is of great significance for ensuring food security. This article systematically reviews the problems of declining fertility, organic matter content, and biodiversity in China's medium and low yield fields, and clarifies the focus on the development of ecological improvement materials in the future. This helps to explore the path to improve green, high yield, and efficient production capacity in low to medium yield fields, and promote the achievement of food security and sustainable development goals.
Exploration of the Current Situation and Future Development of the New Energy Industry
Authors: Zhang Jianhua , Zhou Zejiong
Published: November 2023

The report of the 20th National Congress of the Communist Party of China proposed the policy of "actively and steadily promoting carbon peak and carbon neutrality". In order to improve infrastructure construction and promote regional economic development, Bengbu City has actively responded to the national call for energy conservation and emission reduction. However, there are still problems in its application and development, such as imbalanced technological development, unreasonable industrial structure, and low level of technological research and development. Therefore, sorting out the current development status of the new energy industry in Bengbu City and identifying the main factors that affect the development of the new energy vehicle industry in Bengbu City is of great significance for the good development of new energy in Bengbu City. Based on this, this article conducted a research on the current situation and future development of the new energy industry - taking Bengbu City, Anhui Province as an example. This survey mainly focuses on understanding the current development status of the new energy industry in Bengbu City from the perspective of new energy enterprises. Field research and questionnaire survey methods were used to investigate new energy enterprises in Bengbu City. A total of 220 questionnaires were distributed, of which 202 were valid, with an effective percentage of about 92%. Using SPSS software, establish a multivariate ordered logistic regression model and factor analysis model, and combine SWOT analysis method to comprehensively analyze the development of new energy in Bengbu City.
The Effect of Salt-dissolving Growth-promoting Rhizobacteria on the Growth of Pepper
Authors: Chen Weiwei , Luo Yuhu
Published: November 2023

Soil salinization is increasing, which seriously threatens the local ecological environment security and affects the development of social economy. Plant growth-promoting rhizobacteria (PGPR) is the bacterial population isolated from rhizosphere soil that has a growth-promoting effect on plants, which is of great significance for improving salt stress. In this study, pepper was used as the research object, and the effect of salt-dissolving and growth-promoting bacteria on pepper plants was studied by pot experiment. A total of 7 treatments were set up, 0 % salt sterility ( CK-0 % ), 0.5 % salt sterility ( CK-0.5 % ), 0 % salt-hydrolyzed salt-promoted strains ( C-0 % ), 0.5 % salt-hydrolyzed salt-promoted strains ( C-0.5 % ), 1 % salt-hydrolyzed salt-promoted strains ( C-1.0 % ), 2.0 % salt-hydrolyzed salt-promoted strains ( C-2.0 % ), 5.0 % salt-hydrolyzed salt-promoted strains ( C-5.0 % ). The results showed that : ( 1 ) The germination rate of pepper seeds inoculated with salt-dissolving and growth-promoting strains was significantly increased, and the salt concentration in the soil had no significant effect on the germination rate of pepper seeds. ( 2 ) Inoculation of salt-solubilizing growth-promoting strains and salt concentration in soil also had no significant effect on the plant height of pepper seeds. ( 3 ) The fresh weight and dry weight of pepper plants inoculated with salt-solubilizing and growth-promoting strains were significantly increased. This study has important scientific and theoretical significance for the more rational application of Plant growth-promoting rhizobacteria.
APTM: Structurally Informative Network Representation Learning
Authors: Zhang Pingke , Huang Jinyu
Published: November 2023

Network representation learning algorithms provide a method to map complex network data into low-dimensional real vectors, aiming to capture and preserve structural information within the network. In recent years, these algorithms have found widespread applications in tasks such as link prediction and node classification in graph data mining. In this work, we propose a novel algorithm based on an adaptive transfer probability matrix. We use a deep neural network, comprising an autoencoder, to encode and reduce the dimensionality of the generated matrix, thereby encoding the intricate structural information of the network into low-dimensional real vectors. We evaluate the algorithm's performance through node classification, and in comparison with mainstream network representation learning algorithms, our proposed algorithm demonstrates favorable results. It outperforms baseline models in terms of micro-F1 scores on three datasets: PPI, Citeseer, and Wiki.
Determination of Trace Mercury in Geological Samples by Atomic Fluorescence Spectrometry
Authors: Li Risheng
Published: November 2023

An atomic fluorescence method was established for the determination of mercury in geological samples. After sample digestion, mercury reacts with potassium borohydride in a specific medium to produce volatile hydride. The fluorescence of characteristic wavelength is emitted under the irradiation of argon loaded quartz atomizer light source, and the fluorescence intensity is proportional to the content of elements.
Research Progress on Soil Carbon Sequestration in Dry Farmland
Authors: Sun Yutong , Zhang Jinyang
Published: November 2023

Dry farming is a kind of agricultural production mode widely existed in the world, and its soil carbon sequestration potential has attracted much attention. The paper discussed the influencing factors, carbon sequestration process and effect of soil carbon sequestration in dryland farmland. It was concluded that protective tillage measures such as application of organic fertilizer, no-tillage, deep tillage and straw returning could increase the carbon sequestration in surface dryland soil, biodegradable film mulching could promote soil organic carbon fixation, and rational arrangement of crops could improve soil carbon sequestration capacity.
Practical Exploration of Integrating Ideological and Political Education into Engineering Economics Teaching
Authors: Ding Huajun , Tang Genli , Zhang Heng
Published: November 2023

Engineering economics is one of the core professional courses offered in engineering majors, which is of great significance in cultivating students' basic engineering literacy and management decision-making ability. In the context of the "Three Comprehensive Education" and curriculum ideological and political education, curriculum teaching has become an important battlefield for universities to achieve their educational goals. It is imperative to integrate ideological and political elements into the teaching of engineering economy courses. Starting from the nature of engineering economics courses, this article points out the problems in traditional teaching of engineering economics, explores the integration methods and specific practices of ideological and political elements in professional course teaching, and makes course teaching the main channel for "three comprehensive education", effectively improving the effectiveness of ideological and political education.
CHOOSING THE BEST PROJECT MANAGEMENT METHODOLOGY FOR RESEARCH AND DEVELOPMENT PROJECTS: AGILE, WATERFALL, OR HYBRID?
Authors: Iwersen Lian Hua Liu , Zem Leandro , Penteado Neto Renato de Arruda
Published: November 2023

A seleção da metodologia de gestão de projetos mais adequada para uma empresa é uma decisão complexa que requer uma cuidadosa consideração de vários fatores. Este artigo explora os principais fatores que devem ser levados em conta ao escolher uma metodologia de gestão de projetos, incluindo o tipo de projeto, a cultura da empresa, os objetivos e metas, a experiência da equipe e o envolvimento das partes interessadas. Ele discute as vantagens e desvantagens das metodologias tradicionais (cascata), ágeis e híbridas. O artigo também apresenta os benefícios do uso de metodologias para evitar erros, reduzir custos, mitigar riscos e identificar erros precocemente. Além disso, ele discute as características dos projetos de tecnologia, inovação, pesquisa e desenvolvimento e a importância de escolher a metodologia adequada para tais projetos. O método Analytic Hierarchy Process (AHP) é sugerido para avaliar e selecionar a melhor metodologia de gestão de projetos para projetos de pesquisa e desenvolvimento. Adicionalmente, o artigo introduz o Cynefin Framework como uma ferramenta para determinar a abordagem mais adequada com base no contexto do projeto. Ele conclui que uma metodologia híbrida é bem adequada para projetos complexos, combinando boas práticas e técnicas emergentes de gestão de projetos. O uso de uma abordagem híbrida permite flexibilidade e adaptabilidade na entrega do projeto, aproveitando os pontos fortes de ambas as metodologias ágil e cascata. Em geral, a escolha da metodologia de gestão de projetos depende das necessidades e características específicas de cada projeto e empresa.
High-dose chemotherapy with autologous stem-cell transplantation for relapsed metastatic germ cell tumors
Authors: Zhang Hanbo , Alimohamed Nimira S. , Basappa Naveen S. , Cheng Tina , Chu Michael , Cox-Kennett Nanette , Ernst D. Scott , Fontaine Amelie , Ghosh Sunita , Heng Daniel Y.C. , Littleton Richard , North Scott , Railton Cindy , Sandhu Irwindeep , Stenson Trevor H. , Stewart Douglas A. , Venner Christopher , Venner Peter C. , Kolinsky Michael P.
Published: November 2023

Introduction: High-dose chemotherapy with autologous stem-cell transplantation (HDC-ASCT) is standard therapy for metastatic germ cell tumors (mGCTs) in patients whose disease progresses during or after conventional chemotherapy. We conducted a retrospective review of HDC-ASCT in relapsed mGCT patients in the province of Alberta, Canada over the past two decades.
Methods: Patients with mGCTs who received HDC-ASCT at two provincial cancer referral centers from 2000–2018 were identified from institutional databases. Baseline clinical and treatment characteristics were collected, as well as overall survival (OS) and disease-free survival (DFS). Relevant prognostic variables were analyzed.
Results: Forty-three patients were identified. The median age was 28 years (range 19–56). A majority (95%) had non-seminoma histology and testis/retroperitoneal primary (84%). Twenty patients (47%) had poor-risk disease, as per The International Germ Cell Consensus Classification (IGCCC), at start of first-line chemotherapy. HDC-ASCT was used as second-line therapy in 65% of patients, and 58% of ASCT patients received tandem transplants. Median followup after ASCT was 22 months (range 2–181). At last followup, 42% of patients were alive without disease, including 3/7 (43%) of patients with primary mediastinal disease. Two-year and five-year DFS/OS ratios were 44%/65% and 38%/45%, respectively. Median OS and DFS for all patients were 30.0 months (13.3–46.6) and 8.0 months (0.9–15.1), respectively.
Conclusions: We found that HDC-ASCT is an effective salvage therapy in mGCT, consistent with existing literature. Patients appeared to benefit regardless of primary site. Though limited by small sample size, we found a numerical difference in DFS and OS between second- and third-line HDC-ASCT and single vs. tandem ASCT.