bluuebunny/crossref_metadata_2025 huggingface dataset:
World War II and Socialist Integration: In Search of the Theoretical Foundations for Building the Socialist Bloc (1940–64)
Authors: Nenovsky Nikolay , Marinova Tsvetelina
Published: August 2024

This article presents the development of ideas on coordination between countries with socialist economic systems during World War II and in its immediate aftermath (1940–64). It studies the theoretical models of Hoselitz and the debates on the possibilities of interaction between socialist states after the war, as well as the first attempts to develop integration within the framework of the CMEA, or the Council for Mutual Economic Assistance, in practice. The lack of a clear theory made these processes difficult. Yugoslav economists considered nonequivalent exchange within the Marxist paradigm and attempts to create a monetary zone of the ruble encountered difficulties from the outset. Monetary reforms in socialist countries showed the need to adapt to the world (capitalist) market.
Economic Expertise at War: A Brief History of the Institutionalization of French Economic Expertise (1936–46)
Authors: Caldari Katia , Legrand Muriel Dal Pont
Published: August 2024

French economic expertise developed significantly during the interwar period when economic issues, and particularly those resulting directly from World War I, became the overriding concern for Europe's democracies. Before the end of World War II, three major institutes of conjuncture had been created, all of them driven by the need for economic policy indicators. ISRES was established in 1933 by Charles Rist, the Institut Français de la Conjoncture was founded in 1938 by Alfred Sauvy, and ISEA was founded in 1944 by François Perroux. Not surprisingly, all three were working on productivity measures. From 1936, debate was focused on the issue of the forty-hour week and then moved to the context of the arms race and the preparation for an inevitable war. The war period resulted in shortages that required planning of production; and in the postwar period the focus was on plans for the reconstruction of France and then Europe more generally. All these periods generated demand for differentiated economic expertise in productivity. In 1946, the first French National Accounts were published alongside the establishment of the Commissariat Général au Plan and INSEE, which resulted in another distinct period.
World War II and Industrialization Policies in Latin America: The Cases of Argentina and Brazil
Authors: Calcagno Adriana , Duarte Pedro Garcia
Published: August 2024

Raúl Prebisch and Celso Furtado were two important contributors to development economics and to the theories and policies defended by the United Nations Economic Commission for Latin America (ECLAC). In this article, we argue that understanding their ideas, and how industrialization became a key concern, requires paying closer attention to the geopolitical changes brought by World War II. We discuss how Argentina and Brazil, their home countries, navigated the troubled waters brought by the war and the international trade disruptions and turned state-led industrialization into a key development strategy. After the war, the United States became the new hegemonic power and adopted a universalist foreign policy, based on the newly created international agencies. At home, the internationalist businessmen promoted the partnership capitalism that became central to the foreign policy during the Truman administration and onward, making industrialization a key interest. Internationalism was also what Latin American countries used to counteract the US hegemony even before the war, which culminated in the creation of ECLAC after the war. The intellectual paths of Prebisch and Furtado toward industrialization policies were shaped by the changing international order and by local developments in their countries including the building of a more scientific statistical system that would better help the state to design development policies.
Economic Responses to Nazi Aggression in Europe: Albert Hirschman and Paul Rosenstein-Rodan on the Economic Sovereignty of Central and Eastern Europe
Authors: Alacevich Michele
Published: August 2024

Germany's expansion in Central and Eastern Europe was not just one among many aggressive moves by the Third Reich but the central strategy of the Nazi imperial project on the continent. Prominent economists, politicians, and think tanks agreed that crucial to this project was Germany's economic domination of the area, and they committed to developing a new vision for a postwar international order that avoided the instability and turmoil of the interwar years. This article discusses the analyses of the crisis of Central and Eastern Europe and solutions to it that Albert Hirschman and Paul Rosenstein-Rodan, then both virtually unknown and working independently one from the other, produced during World War II—Hirschman with a focus on the international dimension and Rosenstein-Rodan with a focus on the domestic one. This article offers a synthetic discussion of how the war deeply affected their economic thinking and how, in turn, their analyses became foundational elements of new and important disciplinary fields in the postwar decades, such as international political economy and development economics.
Forgettable Black and Amazigh Bodies
Authors: El Guabli Brahim
Published: August 2024

Boujemâa Hebaz (1943–1981), a Black and Amazigh professor at Mohammed V University, was forcibly disappeared in 1981. This article reads the irresolution of his case against the background of exclusion and amnesia that surrounds the fate of Black and Amazigh people in southeast/southwest Morocco. I argue that Hebaz's case reflects a wider history of absence, disappearance, and discrimination that impacts Black Amazigh Moroccans. Hebaz straddled identities that were simply disregarded throughout the Years of Lead (1956–1999). When the Moroccan police kidnapped Hebaz in April 1981, they were aware that he was from the southeast, an area that is not only predominantly Amazigh and Black but a region that had already been turned into a large prison for political detainees. The presence of several notorious secret prisons further exacerbated the region's territorial marginalization and disconnection from the rest of Morocco. This fact would later be officially acknowledged in the final Equity and Reconciliation Commission's (ERC) report and recommendations. Drawing on interviews, authentic materials, ERC reports, and other sources, the article demonstrates how Hebaz's absence is enmeshed in racism, territorial marginalization, and historical amnesia in Morocco.
Empowering the “Ecosystem”
Authors: Tobias Zak
Published: August 2024

This article draws upon original research including a series of interviews, extensive desk research, and a canon of political economy scholarship hailing from Lebanon and elsewhere to explore the political dynamics underpinning Lebanon's emerging tech “ecosystem.” It focuses on a seemingly peripheral actor within this ecosystem, the coding school, both as a window into the ecosystem's political machinery and as a surprisingly important site through which its wider interests are mediated. This focus explores how the coding school generates so-called empowerment conceived largely in terms of training and preparing Lebanon's “underprivileged youth” for global tech markets, through a strategic alignment with the ecosystem. Thus, empowerment becomes a political currency of sorts, helping to reify and repackage an enclave of Lebanon's economy. The article suggests that the political work to engineer this new economic landscape reflects how state-business interests come together to repackage so-called development and enforce new regimes of accumulation at a time of deepening crisis.
Gene Expression Changes Associated With Recurrence After Gross Total Resection of Newly Diagnosed World Health Organization Grade 1 Meningioma
Authors: Morshed Ramin A. , Nguyen Minh P. , Youngblood Mark W. , Perlow Haley K. , Lucas Calixto-Hope G. , Patel Akash J. , Palmer Joshua D. , Chandler James P. , Theodosopoulos Philip V. , Magill Stephen T. , Chen William C. , Raleigh David R.
Published: August 2024

BACKGROUND AND OBJECTIVE:

Patients who undergo gross total resection (GTR) of Central Nervous System World Health Organization (WHO) grade 1 meningioma constitute a “low-risk” group, but some low-risk meningiomas can recur despite reassuring clinical and histological features. In this study, gene expression values in newly diagnosed WHO grade 1 meningiomas that had undergone GTR were evaluated for their association with recurrence.

METHODS:

This was a retrospective, international, multicenter cohort study that included WHO grade 1 meningiomas that underwent GTR, as first treatment, based on postoperative magnetic resonance imaging. Normalized gene expression values from a previously validated 34-gene panel were evaluated for their association with recurrence. Kaplan-Meier, multivariable Cox proportional hazard analyses, and K-means clustering were performed to assess the association of genes of interest with recurrence and identify molecular subgroups among clinically and histologically low-risk meningiomas.

RESULTS:

In total, 442 patients with WHO grade 1 meningiomas that underwent GTR and had available gene expression profiling data were included in the study. The median follow-up was 5.0 years (interquartile range 2.6-7.7 years), local recurrence occurred in 36 patients (8.1%), 5-year local freedom from recurrence was 90.5%, and median time to recurrence was 2.9 years (range 0.5-10.7 years). Eleven genes were associated with local recurrence, including lower expression of ARID1B, ESR1, LINC02593, PGR, and TMEM30B and higher expression of CDK6, CDKN2C, CKS2, KIF20A, PGK1, and TAGLN. Of these genes, PGK1 had the largest effect size. K-means clustering based on these 11 genes distinguished 2 molecular groups of clinically and histologically low-risk meningiomas with significant differences in local freedom from recurrence (hazard ratio 2.5, 95% CI 1.2-5.1, P = .016).

CONCLUSION:

Gene expression profiling may help to identify newly diagnosed WHO grade 1 meningiomas that have an elevated risk of recurrence despite GTR.
Realizing Textbook Outcomes Following Liver Resection for Hepatic Neoplasms with Development and Validation of a Predictive Nomogram
Authors: Gundavda Kaival K. , Patkar Shraddha , Kannan Sadhana , Varty Gurudutt P. , Nandy Kunal , Shah Tanvi , Polusany Kaushik , Solanki Sohan Lal , Kulkarni Suyash , Shetty Nitin , Gala Kunal , Ostwal Vikas , Ramaswamy Anant , Bhargava Prabhat , Goel Mahesh
Published: August 2024

Background

‘Textbook Outcome’ (TO) represents an effort to define a standardized, composite quality benchmark based on intraoperative and postoperative endpoints. This study aimed to assess the applicability of TO as an outcome measure following liver resection for hepatic neoplasms from a low- to middle-income economy and determine its impact on long-term survival. Based on identified perioperative predictors, we developed and validated a nomogram-based scoring and risk stratification system.

Methods

We retrospectively analyzed patients undergoing curative resections for hepatic neoplasms between 2012 and 2023. Rates of TO were assessed over time and factors associated with achieving a TO were evaluated. Using stepwise regression, a prediction nomogram for achieving TO was established based on perioperative risk factors.

Results

Of the 1018 consecutive patients who underwent liver resections, a TO was achieved in 64.9% (661/1018). The factor most responsible for not achieving TO was significant post-hepatectomy liver failure (22%). Realization of TO was independently associated with improved overall and disease-free survival. On logistic regression, American Society of Anesthesiologists score of 2 (p = 0.0002), perihilar cholangiocarcinoma (p = 0.011), major hepatectomy (p = 0.0006), blood loss >1500 mL (p = 0.007), and presence of lymphovascular emboli on pathology (p = 0.026) were associated with the non-realization of TO. These independent risk factors were integrated into a nomogram prediction model with the predictive efficiency for TO (area under the curve 75.21%, 95% confidence interval 70.69–79.72%).

Conclusion

TO is a realizable outcome measure and should be adopted. We recommend the use of the nomogram proposed as a convenient tool for patient selection and prognosticating outcomes following hepatectomy.
From pioneers to pensioners: Addressing aging populations in Israeli kibbutzim
Authors: Tobiasz-Lis Paulina , Lis Piotr , Perez Avi
Published: August 2024

The kibbutz (pl. kibbutzim), deeply rooted in Israeli culture and history, plays an important role in the nation’s narrative as a symbol of communal living and collective values. As demographics shift, the Israeli kibbutz system, originally designed for younger society, is now becoming attractive also for the elderly people. The main aim of this paper is to examine the Israeli kibbutzim’s organisational culture in the context of challenges arising from ageing society. Drawing on Edgar Schein’s three-level model of organisational culture, the research sheds light on the shared services provided for the elderly, their participation in community life, decision-making processes, and the overall attitude of the kibbutz towards its older members. The study contributes to broader discussions on ageing, silver economy, community welfare, and sustainable development. First, a multi- modal approach in collecting and analysing data has been applied by using literature, documents, and statistics concerning all 266 Israeli kibbutzim identified at the end of 2023. In the second phase, the survey questionnaire with each question intentionally designed to reflect particular issues within Schein’s model was conducted in randomly selected settlements. Responses provide valuable insights into the dynamic interplay of traditional communal values and their modern adaptations. Schein’s model has proven practical in unravelling the complex tapestry of cultural elements that define kibbutzim, showcasing their unique blend of tradition and modernity.
Drug design of novel selective inhibitors targeting lipoxygenase enzyme and molecular study on the mechanism of action of anti-hypertensive drugs
Authors: Χοντζοπούλου Ελένη
Published: August 2024

Σε αυτήν τη διδακτορική διατριβή εφαρμόστηκε ένας συνδυασμός πειραματικών και υπολογιστικών μεθόδων με στόχο να ερευνηθεί η μοριακή δράση υποψηφίων και εμπορικά διαθέσιμων φαρμάκων. Όσον αφορά τον πρώτο άξονα της διατριβής, εκτέστηκαν in silico υπολογισμοί για την ανακάλυψη νέων μορίων-αναστολέων της 5-λιποξυγονάσης (5-LOX). H 5-LOX αποτελεί ένα ένζυμο που ευθύνεται για την απελευθέρωση πρόδρομων μορίων της φλεγμονής στο κύτταρο. Σχετίζεται με πολλές διαφορετικές ασθένειες, όπως το άσθμα, η νόσος Αλτσχάιμερ και ο καρκίνος, ενώ ο μόνος εμπορικά διαθέσιμος αναστολέας του ενζύμου, ο οποίος χορηγείται για την καταπολέμηση του άσθματος, το zileuton, δεν παρουσιάζει ευνοϊκές φαρμακοκινητικές ιδιότητες και προκαλεί ηπατοτοξικότητα. Επομένως, ο στόχος ήταν να ανακαλυφθούν νέες ενώσεις που στοχεύουν την 5-LOX, οι οποίες προσδένονται στο ένζυμο με τον ίδιο τρόπο με το zileuton. Ο σχεδιασμός νέων ενώσεων ξεκίνησε με μια έρευνα επανατοποθέτησης των φυσικών και τεχνητών γλυκαντικών ως προς τη δράση τους στην LOX, όπου αποδείχθηκε η ασπαρτάμη ως ένας ικανός LOX αναστολέας. Με στόχο της εξάλειψη των μεταβολιτών της ασπαρτάμης για τους οποίους υπάρχουν προβληματισμοί ως προς την ασφάλειά τους, σχεδιάστηκαν 12 ενώσεις με βάση τμήμα του δομικού σκελετού της ασπαρτάμης, οι οποίες εξετάστηκαν με in silico και in vitro μεθόδους. Τα αποτελέσματα υπέδειξαν ότι δύο απ’ αυτές τις ενώσεις εμφάνισαν αναταλτική δράση κατά της 5-LOX. Όσον αφορά το δεύτερο άξονα της διατριβής, το εμπορικά διαθέσιμο αντιϋπερτασικό φάρμακο, ιρβεσαρτάνη, μελετήθηκε με στόχο τη βελτίωση των φαρμακολογικών του ιδιοτήτων και την αποκάλυψη του μηχανισμού δράσης του. Η κύρια υπόθεση ως προς τον μηχανισμό δράσης προτείνει ότι το φάρμακο αρχικά εισέρχεται στη λιπιδική διπλοστοιβάδα και στη συνέχεια διαχέεται αργά προς τον διαμεμβρανικό υποδοχέα-στόχο, σε αντίθεση με την υπόθεση ότι το φάρμακο εισέρχεται απευθείας στον υποδοχέα. Επομένως, η ιρβεσαρτάνη εγκλείστηκε σε ένα μόριο-μεταφορέα 2-υδροξυπρόπυλο-β-κυκλοδεξτρίνης ώστε να βελτιωθούν οι φαρμακολογικές της ιδιότητες, ενώ μελετήθηκαν οι μοριακές της αλληλεπιδράσεις και η απελευθέρωσή της στη λιπιδική διπλοστοιβάδα με in silico και NMR μεθόδους. Τέλος, η έρευνα υπέδειξε ότι η ιρβεσαρτάνη απελευθερώνεται από τον μεταφορέα της και αποκαλύφθηκε η επικρατούσα διαμόρφωση του φαρμάκου στο εσωτερικό των λιπιδίων.
Evaluation by app in smartphones of awake bruxism at the return of presential classes in two university centers
Authors: Velasquez Ron Byron , Mosquera Cisneros Veronica , Pazmiño Troncoso Pamela , Rodriguez Tates Maria , Alvares Lalvay Eddy , Chauca  Bajaña Luis , Ordoñez Balladares Andrea
Published: August 2024

Background. The return to normality post-pandemic brought some inconveniences to the population, especially students. To evaluate the frequency of awake bruxism behaviors through the use of an app on smartphones in dental students returning to presential classes. Awake bruxism was evaluated with the creation of an app that according to the authors evaluates: relaxed jaw muscles, dental contact, jaw effort, clenching teeth and teeth grinding, 5 frequent oral conditions in the population. The frequency of awake/daytime bruxism (AB) in healthy individuals when comparing other populations with possible risk factors for additive bruxism (psychological factors, depression, suicide delusions, etc.), evaluating consequent clinical signs (fatigue, muscle pain, attritions and dental openings). Methods: The sample of three hundred (n=300) young adults legally enrolled in two Ecuadorian universities, the sample was selected among fifth, sixth, seventh, eighth and ninth semester students legally enrolled and who are attending Faculty of Dentistry classes in 2 different cities (Quito and Guayaquil). The app was configured to provide 20 alerts during the day x seven days a week, in real time. Results. The study obtained 95% reliability and 5% error in research, was used. The relaxation condition was present in all users, but 40% of the alerts were associated with jaw and tooth discomfort, 39% corresponded to the discomfort of mandibular clenching, and 24% corresponded to tooth contact. A direct significant association was found between the state of relaxation and nonrelaxation, with a high probability of reports related to nonrelaxation (p ≤ 0.05). Conclusions: Awake bruxism with the app was evaluated, identifying 5 behaviors such as: relaxed mandibular muscles, dental contact, mandibular effort, clenching and grinding teeth, frequent conditions in the population; reporting a state of mandibular relaxation, there is a high probability that a condition of nonrelaxation would be reported (p≤0.05).
Evaluation of the impact of the educational revolution in Peru and the gender wage gap, 2017-2021
Authors: Castro Mejía Percy Junior , Morán Santamaría Rogger Orlando , Llonto Caicedo Yefferson , Cúneo Fernández Francisco Eduardo , Lizana Guevara Nikolays Pedro , Arias Gonzales Hilda Paola , Vela Meléndez Lindon
Published: August 2024

Background Women’s educational attainment and their generation of value through education has increased the prospects for achieving economic equality between men and women. However, women continue to earn lower wages than men, reflecting growing inequality in several countries. Therefore, the objective of the study is to estimate the impact of education on the gender wage gap in Peru over the period 2017-2021. Methods Quantitative, explanatory study aimed at identifying the impact of education on the gender wage gap in Peru during the period 2017-2021. The research design is non-experimental and uses a time series that analyses the influence of the latent variable of education on the gender wage gap. This is a continuous variable to estimate the Tobit model. Results The results show that the gender gap in Peru exhibited a decreasing trend between men and women during the period 2017-2020, with an average reduction of 10% until 2020 due to the health crisis. The highest average salary was achieved by men in 2019, reaching S/2289.97 soles, while women reached an average salary of S/1368.85 soles. In the post-pandemic scenario for 2021, the gender gap increased by 3%, with men earning an average salary of S/1999.63 soles and women earning an average salary of S/1281.16 soles. The analysis from 2017-2021 shows that years of education had a positive impact on the gender wage gap in Peru based on the Tobit model estimation. Conclusions During the analysis period of 2017-2021, years of education had a positive impact on the gender wage gap in Peru, with the greatest impact occurring during the health crisis. The probability of women’s incomes improving with an increase in years of education was 2.35%, while for men, the highest impact was in 2018, with a probability of income improvement of 2.16% in terms of marginal effect.
The sound of war: A comparison between Apocalypse Now (1979) and Farha (2021)
Authors: Al-Hor Abdulla
Published: August 2024

For a long time, filmmakers have used war movies as a potent tool for probing the human condition, the results of battle, and the psychological effects of war on individuals and communities. While Apocalypse Now (1979) by Francis Ford Coppola and Farha (2021) by the contemporary director Darin Sallam both explore the raw reality of battle, they were made decades apart. In this comparison, we will look at how both movies use sound to express the fright and tragedy of battle. This study examines the political context, setting, style of music, style of direction, and conclusion of two war films and finds many points of similarity between them. The argument made in this report is that regardless of the historical and contextual distinctions between the Vietnam War and the Palestinian Nakba, Apocalypse Now and Farha successfully portray the experiences of people and the long-lasting effects of war, surpassing the particular actual incidents they present.
The Value of Improving Chinese Piano Education
Authors: Zhang Xianhua
Published: August 2024

In China in the past, the piano belonged exclusively to princes and nobles, but now it has entered thousands of homes of ordinary people. Countless preschool children have started learning to play the piano with the support of their parents and teachers. According to incomplete statistics, the share of pianos in China has exceeded two million units, which is one tenth of the total in the world. Currently, at least one million people in China are learning to play the piano, of which beginners and young students make up the majority. Today, in the field of education, the piano has become one of the musical instruments of many learning enthusiasts in China. The piano has become a hot topic in society after reform and openness. In 2023, the fifth International Piano Art Festival was successfully held in the Futian district of Shenzhen. China has turned Shenzhen into a “piano city” and this theme has become a big focus in Shenzhen. Then, with such a tense status quo, the problem of piano education in China arose. The text below contains a discussion of this issue.
The principle of value conformity of education
Authors: Yakovlev Sergey
Published: August 2024

The article presents for the first time the principle of value conformity of education, interconnected with the classical principles of environmental conformity and cultural conformity of education. The principle of value conformity of upbringing is based on the pattern of age-related development of the individual’s value system and is a logical consequence of the principle of cultural conformity of education. Practical examples of the implementation of the principle of cultural conformity of education in the development of a program of spiritual and moral education for primary school students are given.
Spiritual and moral ideas of the pedagogical system of professor S.A. Rachinsky
Authors: Zharov Sergey
Published: August 2024

The article examines the variety of pedagogical approaches to the education of schoolchildren in the creation of a “dormitory” school with the involvement of Christian directions in the education of the younger generation in the pedagogical system of the famous methodologist Professor Sergei Aleksandrovich Rachinsky in his built school by himself. His methodological guidelines were constantly combined with solving of the problems of moral education of schoolchildren to form a Christian worldview towards the world around him.
Teacher-Family Partnership for Primary School Parenting
Authors: Ryabova I.
Published: August 2024

The article discusses the leading areas of implementation of the partnership between the class teacher and the family on the education of primary schoolchildren and the results of research on this problem. The partnership of the school and parents is the creation of conditions for the formation of personality, self-determination and socialization of the child. Today, the school and family, as social institutions, as equal subjects of upbringing of the younger generation, are tasked with fostering patriotism and citizenship; assignment of norms, values and traditions of Russian society. Partnerships are seen as unity the goals and values of family and school education. The interaction of the class teacher and parents allows you to jointly identify, realize and solve the problems of raising children, and also provides the necessary deep connections between adults in the context of the development of the child's personality.
Private school and inclusion: towards the choice  of educational organization by parents
Authors: Kananchev Z.
Published: August 2024

The article explores the aspect of inclusion, integration and promotion of diversity in education. Features of introducing the inclusion principle in OECD educational systems are considered. It has been determined that non-public educational institutions have more significant opportunities in providing special conditions required for children with limited abilities to learn and having other personal distinctive characteristics. The problem of unequal treatment of inclusive education on the part of parents with children, who have no distinctive characteristics and who want to study in the so-called «normal development environment» is noted. In contrast to understanding of the inclusion principle in OECD countries, the Russian Federation implies, first of all, the category of children with disabilities for health. The article concludes that it is necessary to implement this principle smoothly, in order to meet the needs of all parents when choosing a school for their children.
A PROJECT-BASED APPROACH TO THE ORGANISATION OF MENTORING IN MODERN EDUCATION
Authors: Lyaus Yuliya , Borodina Ekaterina
Published: August 2024

The effective functioning of the mentoring system requires a combination of the professionalism of a teacher or a full-time university employee with an understanding of the peculiarities of youth psychology. With the right approach, this can significantly increase the effectiveness of the educational process and favorably affect both the student's personal development and the formation of his professional training.
Assessment of Priorities for the Use of Program Budget Expenditures in the Regions of the Russian Federation
Authors: Pechenskaya-Polischuk M.
Published: August 2024

This article is devoted to the search for an answer to the question whether the promotion of socio-economic development is among the key priorities of using the budget potential of the subjects of the Russian Federation. To solve this problem, the study has developed methodological tools for assessing the use of the budget potential of the region. Mainly, it includes justification of priorities and directions of using the budget potential of the region, determination of the proportion of priorities and its dynamics, calculation of the importance of priorities based on a modified formula of their elasticity according to the maximum achieved budget potential of the region. In practice, the application of the developed methodological tools will make it possible to measure and adjust the ratio of directions and priorities for the use of the budget potential of the region, depending on the goals and conditions of the development of the social sphere and the economy. According to the developed tools, as well as on the basis of official reporting data from the Federal Treasury, the Federal State Statistics Service, and the Ministry of Finance of the Russian Federation, an approbation diagnosis of the use of budget potential was carried out on the example of 85 subjects of the Russian Federation over a 15-year period from 2006 to 2020. It was determined that 7/10 of the realized budget potential of the subjects of the Russian Federation was used for the current priority, 2/10 — for transfer, 1/10 — for investment. The empirical results obtained in the work confirmed the hypothesis that the use of budget resources of regions for short-term stabilization purposes is more important than financing longterm stimulation of socio-economic development of territories. According to the results of the approbation, ways to increase the efficiency of using the budget potential of the region to stimulate its socio-economic development are identified.
Project Management Methodology in the Context of Digital Transformation of the Enterprise
Authors: Tashkinov A.
Published: August 2024

The article examines the Agile methodology, presents its advantages and disadvantages. A new way of interaction between project work participants at the enterprise is proposed. This approach to organizing project work takes into account new challenges of digital transformation and digital solutions aimed at implementing tasks in order to optimize the use of enterprise resources. The considered methodology of project management in the context of digital transformation of the enterprise includes the overall organization of work, effective interaction of participants, the formation of cross-functional working groups in the development of digital transformation projects, the implementation of the digital transformation strategy, and the development of digital culture. The proposed approach made it possible to form a theoretical and methodological basis for understanding the need to create and use cross-functional working groups in the implementation of digital transformation projects.
Public Administration of Sustainable Development: Pattern of Russia and China
Authors: Si Fuyuan' , Baraboshkina A. , Bobyleva Alla
Published: August 2024

The article examines modern forms of public administration of sustainable development in Russia and China. It has been revealed that national projects predominate in Russia. This framework allows to focus on solving strategic problems and to use project approach technologies for the comprehensive implementation of development priorities. In its turn, China’s strategy is characterized by support of implementation of the sustainable development goals through the adoption of specific regulatory documents for each goal and the identification of funding sources for each goal. The research shows that mutual enrichment with proven management technologies will allow both countries to implement national sustainable development goals in less time, solve common problems in border regions, influence international discourse in a multipolar world, and intensify global cooperation.
Local anesthesia as an alternative to general anesthesia in ENT surgery – a review of selected procedures
Authors: Parfianowicz Agnieszka , Surma Alicja , Jaworski Arkadiusz , Grajnert Filip , Plizga Jakub , Głuszczyk Agnieszka , Cecot Jakub , Zarzecki Konrad , Mandryk Miłosz , Holdun Nazar
Published: August 2024

Surgeries and procedures in otolaryngology require close collaboration between anesthesiologists and ENT specialists, especially for operations involving the larynx and airways, which pose challenges for maintaining airway patency and visibility. Choosing the type of anesthesia, whether general or local, is crucial. This study examines the benefits and drawbacks of both types of anesthesia in tonsillectomy and adenoidectomy, tympanostomy and myringotomy, and flexible endoscopic biopsy of the pharynx and larynx. A review of current guidelines, systematic reviews  and relevant clinical cohort studies was conducted. The findings highlight several advantages of local anesthesia, including shorter operation times, reduced hospital stays, lower costs, decreased use of analgesics, and improved patient comfort.
Preeclampsia - the leading cause of maternal and neonatal mortality in the world - review of literature
Authors: Staszczak Paweł , Różańska-Smuszkiewicz Gabriela , Smuszkiewicz-Różański Paweł , Jaworska Barbara , Kmiotek Weronika , Oronowicz Radosław , Ragan Dagmara , Pażyra Aldona , Kusak Natalia , Żak Natalia , Stanicki Paweł
Published: August 2024

Background: This review analyzes current knowledge on the pathophysiology, prevention and art of treatment of preeclampsia. Preeclampsia (known as EPH-gestosis) is nowadays the leading cause of maternal and neonatal mortality in the world. According to statistics it affects up to 5% of pregnant women. The symptoms are high blood pressure, edema, proteinuria. The scientists all over the world are trying their best to know the pathogenesis to devise a cure for the disease.
Aim of study: The goal of this article was to gather information about the pathophisiology and treatment of preeclempsia to prevent the risk of ilness’ development.
Materials and methods: A review of the literature available in the “PubMed”, Google Scholar and Medline databases. The search was performed by using following keywords: “preeclampsia”, “ophthalmic artery doppler”, “PIGF”, “aspirin”, “placenta”.
Results and conclusions: In spite of the progress of science the preeclampsia is still a serious threat for pregnant women all around the world. Thank to the advanced molecular and ultrasonographic techniques the doctors can estimate the risk of complications. The most important is screening, which helps the doctors to define the group of risk and then launch the treatment. That should decrease the amount of maternal and neonatal complications and deaths.
Assessing the safety and efficacy of probiotics in improving the gut microbiome of premature infants
Authors: Orłowska Dominika , Olszak Joanna , Zalewa Karolina , Bartoszek Lidia , Kapłan Wojciech , Starownik Jakub
Published: August 2024

Introduction and PurposeThe gut microbiome is crucial to infant health and development. For premature infants, microbiome development differs from full-term babies, posing long-term health risks. Factors such as delivery method, feeding, antibiotic treatment, and neonatal intensive care unit (NICU) environment significantly influence the microbiome of premature infants. Probiotics, especially Bifidobacterium strains, show promise in enhancing health and reducing risks of necrotizing enterocolitis (NEC) and late-onset sepsis (LOS).Material and MethodsThis review is based on articles from the PubMed database, covering the years 2004-2023, using keywords: gut microbiome, premature infants, probiotic, microbiome development, and neonatal intensive care unit.ResultsCurrent research indicates probiotics, particularly Bifidobacterium strains, positively impact the gut microbiome of premature infants, improving immunity and metabolism, and providing protection against NEC and LOS. Multi-strain probiotic preparations combining Bifidobacterium and Lactobacilaceae strains appear promising, but further research is needed to fully understand their effects. Addressing food intolerance (FI) in premature infants is another potential application of microbiome-focused therapies.ConclusionsWhile probiotics show promise in improving the microbiome of preterm infants, comprehensive research on single and multi-strain probiotics and their specific mechanisms of action is needed. Controversies persist regarding the safety, FDA regulation, and selection of specific probiotics and formulations. There is no consensus on the optimal timing for introducing probiotics. Further research is required to optimize probiotic selection and determine the best benefits. Enhanced standardization and oversight are essential to ensure safe and effective use of probiotics in neonatal healthcare.
Energy drinks: is there anything to be concerned about? A review of the literature with attention to the value of drinks among athletes
Authors: Witkowska Maria , Skotnicka Joanna , Błaszczak Karolina , Turek Monika , Jaroń Aleksandra , Jastrzębska Katarzyna , Wojciechowska Klara , Borkowski Adrian , Sawicki Mateusz
Published: August 2024

Introduction:
Popular energy drinks containing caffeine, taurine or guarana are currently generating a lot of interest. Their supply is an increasingly popular method of boosting the body. Therefore, it is important to know the effects of such drinks on health.
Objective:
A review of the literature on the health effects of energy drinks with a focus on the value of their consumption in athletes.
Current Knowledge:
Many studies have been made and numerous medical cases have been analyzed to assess the health effects of energy drinks. The most commonly described complications are those involving the cardiovascular and neurological systems, but there are also cases of gastrointestinal, kidney, gynecological or skin diseases. The severity of these complications depends on the amount of energy drinks consumed and the time interval in which they were drunk. Nowadays, athletes are increasingly turning to energy drinks to boost their performance.  It is also noticeable that children and adolescents who should not consume caffeine or sugar in excess consume this type of drink.
Conclusions:
The growing popularity of energy drinks, including among professional athletes as well as children and adolescents, is leading to an increasing number of complications due to their excessive consumption. Therefore, further research on their health effects and harmfulness is needed to determine their safe use.
Use of rimegepant as an alternative to triptans in migraine treatment
Authors: Jaroń Aleksandra , Jastrzębska Katarzyna , Witkowska Maria , Skotnicka Joanna , Błaszczak Karolina , Turek Monika , Wojciechowska Klara , Borkowski Adrian , Sawicki Mateusz
Published: August 2024

Introduction and aim of study: Migraine is a chronic neurological disorder that is considered one of the leading causes of disability worldwide. Increasing evidence indicates that the calcitonin gene-related peptide (CGRP), a neuropeptide released during trigeminal nerve activation, plays a major role in pathophysiology and serves as an important therapeutic target. Rimegepant is an antagonist for the receptor of this peptide and an alternative to the commonly used triptans.
Materials and Methods: Two databases, Pubmed and Medline, were searched using the terms "rimegepant" and "migraine."
Results: By reducing the severity and frequency of migraine attacks, rimegepant significantly improves patients' daily functioning and quality of life. A single 75 mg dose of rimegepant provided better efficacy than placebo in the acute treatment of migraine. Two hours after dosing, significantly more patients in the rimegepant group than in the placebo group reported pain relief (59.3% vs. 43.3%). Rimegepant was also effective in the long term when taken every other day for preventive treatment of migraine and/or as needed for acute migraine treatment. When used, rimegepant was well tolerated in both acute and preventive migraine treatment. The most common adverse events included nasopharyngitis, nausea, urinary tract infection, and upper respiratory tract infection.
Conclusions: Rimegepant is an effective drug for treating migraine attacks, offering quick and long-lasting pain relief with a favorable safety profile, especially for patients with contraindications to triptans. Therefore, rimegepant represents a valuable alternative for patients who do not respond adequately to other available migraine therapies.
Anxiety disorders in schizophrenia - the importance of differentiation and targeted treatment a case report and literature review
Authors: Grajnert Filip , Bińczyk Wiktoria , Dróżdż Olgierd , Siudek Bartosz , Plizga Jakub , Głuszczyk Agnieszka , Kamiński Mateusz , Kuśmierczyk Katarzyna , Karkos Patrycja
Published: August 2024

Schizophrenia is a chronic mental disorder characterized by severe cognitive and behavioral impairments. It often coexists with multiple and complex anxiety symptoms that exacerbate the clinical challenges associated with schizophrenia. This case report presents the history of a 32-year-old woman with a final diagnosis of both paranoid schizophrenia and mixed anxiety disorders. The patient presented with persistent auditory pseudohallucinations, severe anxiety together with occasional panic attacks, which were treated with a variety of antipsychotics. Treatment adjustments were necessitated by the emergence of side effects, including neutropenia, motor disturbances and the observation of major anxiety symptoms, including panic disorder. Ultimately, the successful use of quetiapine in monotherapy was achieved. This case study emphasizes the need for comprehensive treatment strategies to address the complex interplay of psychotic and anxiety symptoms. Increased clinical awareness and targeted treatment of comorbid anxiety can significantly improve the quality of life of patients with schizophrenia.
Medios de comunicación en Perú: análisis de la relación entre edad, nivel educativo, consumo y confianza en los medios
Authors: Rios Incio Felipe Anderson , Páez Ángel , Lisboa Echeverre Gilsa , Gutiérrez Fernández Carlos
Published: August 2024

El artículo investiga cómo las características sociodemográficas, específicamente la edad y el género, se relacionan con el consumo y la confianza de los medios de comunicación en Perú. El estudio tiene un enfoque cuantitativo, es una investigación básica y emplea un diseño correlacional. La muestra fue de 937 ciudadanos de los 25 departamentos de Perú. La técnica de recopilación de datos fue una encuesta y el instrumento propuesto fue un cuestionario virtual. Se utilizó un instrumento validado y puesto a prueba en investigaciones anteriores. Para comprobar las hipótesis de investigación, se manejó el coeficiente de correlación de Spearman. El estudio reveló una correlación positiva moderada entre el consumo de medios de comunicación y la confianza depositada en ellos. Sin embargo, se determinó que ni la edad ni el niv el de escolaridad de los individuos presentan una relación significativa con el consumo de medios o con la confianza en estos. El estudio concluye que, aunque existe una correlación moderada entre el consumo de medios y la confianza en ellos, la edad y el nivel educativo no son factores significativos en el comportamiento de estas variables.
Code and Data Repository for "Learning Hidden Markov Models with Structured Transition Dynamics"
Authors: Ma Simin , Dehghanian Amin , Garcia Gian-Gabriel , Serban Nicoleta
Published: August 2024

The goal of this code is to fit a Hidden Markov Model (HMM) to data with multiple linear constraints imposed on the HMM's transition and emission probability matrices via the LDKB-FISTA algorithm. Alongside our LDKB-FISTA, we have also uploaded the scripts for running Matlab-Fimincon method, as well as the traditional Baum Welch method. The code are written in Matlab.
Humour in forensic services: forging connections between patients and students
Authors: Jones Emma S , Wright Karen M , McKeown Mick
Published: August 2024

Laughter, a joke or banter can be essential to building positive relationships between patients and nurses. Students represent the present and future of mental health nursing, often having more interactions with patients than registered nurses. Despite the many benefits of humour, some considerations must be taken into account, particularly with regards to risk in forensic services. Interest in humour and related interventions in mental health settings began gaining traction over a decade ago, yet there remains limited consideration of the risks and benefits for students and patients in forensic services. This narrative review provides an analysis of the wider literature in the context of interactions shared between patients and student nurses in forensic settings to explore the benefits and risks of the use of humour.
Review article: Telerehabilitation interventions for rehabilitation and management of post-COVID-19 patients: A comprehensive review
Authors:   Pulmonary Function Test Unit, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Promsarn Simaporn , Ketpan Wilawan ,   Nursing Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Pankratuk Rattanapond ,   Pulmonary Function Test Unit, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Suraprapapich Pairoj ,   Division of Physical Therapy, Faculty of Physical Therapy, Mahidol University, Nakhon Pathom, Thailand.
Published: August 2024

The COVID-19 pandemic has posed significant challenges to healthcare systems worldwide, impacting patients during the disease’s acute and post-acute phases. Telerehabilitation has emerged as a promising approach to address the rehabilitation needs of individuals recovering from COVID-19. This comprehensive review examines the effectiveness and feasibility of telerehabilitation strategies for managing post[1]acute COVID-19 symptoms and promoting recovery. Through a systematic review and meta-analysis, various studies have demonstrated the potential benefits of telerehabilitation interventions in improving functional capacity, exercise perception, and quality of life among post-COVID-19 patients. Telerehabilitation programs have been successfully implemented across primary care settings, offering supervised home-based exercise training that targets physical and respiratory functions. Moreover, innovative tools such as mobile applications have been employed to enhance patient engagement and track progress. While the evidence indicates positive outcomes, there is a need for further investigation to explore the effects of telerehabilitation on additional variables such as cardiopulmonary function, anxiety, depression, and long-term outcomes. Despite limitations, telerehabilitation has shown promise in addressing the persistent symptoms and complications associated with post-acute COVID-19 syndrome. The integration of telerehabilitation into clinical care frameworks has the potential to improve patient access, engagement, and overall recovery during the ongoing pandemic and beyond. Continued research and development are essential to optimize telerehabilitation strategies for long-term COVID-19 management.