bluuebunny/crossref_metadata_2025 huggingface dataset:
Ulasan Pementasan Teater Sarah: Paradigma dalam Persembahan, Performance Review: The Paradigm in Performing of Theatre Sarah
Authors:   Malay Languange and Literature Department, Faculty of Languages and Communication, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, MALAYSIA, Mohd Zahari Mohd Amir
Published: December 2021

The first performance of Sarah was presented at the School of Art, Universiti Sains Malaysia on 16 until 18 October 2019. Sarah’s script is the work of Noordin Hassan and directed by Halimi Mohamed Noh. The performance of Sarah is in-conjunction with the 90th anniversary of Malaysian National Laureate, Noordin Hassan. In critically evaluating theatre Sarah from the staging point of view, the production has achieved performance objectives, especially in terms of designing set and spectacle elements. Thus, this article further discusses Noordin Hassan’s patterns of thoughts through his work as well as the actions of the director in highlighting various aspects of staging Sarah.
YAPMA BORCUNUN İFA EDİLMEMESİNE İLİŞKİN TBK m.113/I HÜKMÜNÜN HUKUKİ NİTELİĞİ VE UYGULANMA ŞARTLARI ÜZERİNE BİR DEĞERLENDİRME
Authors: İMAMOĞLU Selma Hülya
Published: December 2021

Türk Borçlar Kanununun genel kısmında yer alan TBK m.113/I hükmü, yapma borcunun alacaklısına mahkemece yetkili kılınmak suretiyle borçlunun ifa etmediği edimi, masrafı (ve hasarı) borçluya ait olmak üzere borçlunun yerine kendisi veya üçüncü kişi aracılığıyla gerçekleştirme imkânını verir. İkame yoluyla ifa olarak da ifade edilebilecek bu süreçte yapma borcunun bir çeşit zorla yerine getirilmesi sağlanır. Bu itibarla alacaklının ikame yoluyla ifaya yetkili kılınması, bir çeşit icra tedbiri olarak ortaya çıkar ve ikame yolu, bir icra aracı oluşturur. Bu yönde TBK m.113/I hükmü, usul hukukuna ilişkin bir icra kuralı niteliğindedir. TBK m.113/I hükmünde yer almamakla birlikte, bir icra aracı olarak görülmesi sebebiyle ve aynı zamanda borçlu yönünden ortaya çıkardığı önemli sonuçlar dolayısıyla ikame yoluyla ifaya izin verilebilmesi için borçlunun edim yükümünün mahkemece açıklığa kavuşturulması gerekir. Diğer bir deyişle alacaklının ikame yoluyla ifaya yetkili kılınmasından önce borçluyu ifaya mahkûm eden bir edim hükmünün alınmış olması gerekir. Türk hukukunda bir işin yapılmasına ilişkin ilâmların icrasında ikame yolu, ayrıca İİK m.30 hükmünde de düzenlenmiştir. Anılan hüküm karşısında TBK m.113/I hükmünün içeriğine uygun bir uygulama imkânı yaratılmalıdır. Bunun için yasal düzenlemeye ihtiyaç vardır.
ROMA HUKUKUNDA AESTIMATUM KURUMUNUN UYGULAMA ALANI ÜZERİNE BİR DEĞERLENDİRME
Authors: KAYAK Sevgi
Published: December 2021

Aestimatum, bir malın ona bir değer biçilerek satılması maksadıyla bir başka kimseye bırakıldığı ve bunun karşılığında malı devralan kimsenin malı sattığı takdirde kararlaştırılan bedelini ödemeyi, satamadığında ise malı iade etmeyi üstlendiği bir sözleşmedir. Roma hukukunda “aestimatum” olarak isimlendirilen bu sözleşme, günümüz hukukunda doktrindeki yaygın ismiyle “satış için bırakma sözleşmesi” olarak bilinir. Aestimatum Klasik hukuk kaynaklarında D.19.3’teki “De Aestimatoria” başlığına ayrılan metinler ile D.19.5’teki “De Praescriptis Verbis” başlığına ayrılan metinlerde düzenlenmiştir. Aestimatum ile ilgili pek çok konu tartışmalıdır. Aestimatum kavramının hukukî niteliği de çok tartışmalıdır. Bize göre aestimatum Klasik hukuktan beri bilinen ve bu dönemde incerti bir dava ile korunan ve Iustinianus hukukunda isimsiz sözleşmeler arasına dahil edilen bir sözleşmedir. Bugünkü hukukumuzda ticarî temsil, ticarî vekillik, pazarlamacılık gibi kurumlar birbirinden ayrılmıştır ve işlevleri de az çok farklılaşmıştır. Oysa Roma’da bu kurumlar kesin çizgilerle birbirinden ayrılmış değildir. Doktrinde ileri sürüldüğü üzere, modern ticaret hukukundaki ticarî temsil, komisyonculuk, pazarlamacılık gibi kurumlara ilişkin boşluk aestimatum tarafından doldurulmuştur.
Analysis of potential factors influencing audit quality: The moderating effect of time budget pressure
Authors: Desta Prasetyo Adi Zainudin Alfareza , Aswar Khoirul , Lastiningsih Noegrahini , Sumardjo Mahendro , Taufik Taufeni
Published: December 2021

In a pandemic situation the audit sector, either government or public, is affected in terms of audit implementation, especially in carrying out field audits. However, auditors can tackle this issue by applying new methods. Therefore, the purpose of this study is to examine the effect of auditor skepticism, auditor competence, understanding of information systems, and auditor motivation on audit quality. It also assesses whether time budget pressure has a moderating effect on the relationship between auditor competence, auditor motivation, and audit quality. 58 questionnaires were issued to government internal auditors in the Principal Inspectorate of Indonesia’s Supreme Audit Institution in the AKN V and VI units, and the data were acquired using a Google Form. SmartPLS software version 3.0 was used to analyze data applying Structural Equation Modelling (SEM). Purposive sampling was used in this investigation, which took a quantitative approach. The paper uses the theory of planned behavior and the inverted U theory. The results conclude that auditor skepticism, auditor competence, and understanding of information systems have a significant positive effect on audit quality. Auditor motivation has no significant positive effect on audit quality. Furthermore, time budget pressure does not moderate the effect of auditor competence and auditor motivation on audit quality. This study is expected to provide valuable input to improve the audit quality and assist auditors in the AKN V and VI units uphold professionalism and integrity in carrying out audit examinations even under the condition of a pandemic.
Community Economic Empowerment through Creative Economic Program in a Business Cooperative in Setu District, Tangerang Selatan
Authors: Syahrullah Syahrullah , Muhtadi Muhtadi
Published: December 2021

This study aims to determine the process and results of empowering the community's economy through the creative economy program at the Cipta Boga Multipurpose Cooperative. This research was conducted using a qualitative research approach with a descriptive type of research. The data collection techniques used, namely: observation, interviews, and documentation studies. Observations were carried out thematically about the process of community empowerment in the creative economy. Five informants were interviewed, consisting of the management of the cooperative and three program beneficiaries. The selection of informants is based on the fact that they know and are involved in empowerment activities. The documentation study was conducted by collecting data on the process and empowerment program in the creative economy sector at the cooperative. This study indicates that community economic empowerment through a paper bag training program can improve the welfare of the Kranggan village community. The Seba Usaha Cipta Boga Cooperative carries out the stages of community empowerment, starting from planning, implementation, institutionalization, and monitoring evaluation. The influence of the training program results can be seen from the behavior and economic life of the community. People get additional income, increase knowledge in entrepreneurship and get activities for entrepreneurship.
Potential of Vegetable E-Commerce for Empowering Farmers in Indonesia
Authors: Pitaloka Atika Dian , Hartoyo Hartoyo , Ali Mochammad Mukti
Published: December 2021

The Covid-19 pandemic has disrupted the flow of horticultural products from farmers to consumers. It causes the delivery of vegetables to be hampered, especially in Jabodetabek, which is the center of vegetable consumption. Therefore, a new marketing strategy is needed involving e-commerce to meet people's need for vegetables. This study discusses the buying behavior of vegetables through e-commerce in Jabodetabek and analyzes the role of e-commerce platforms to empower farmers in Indonesia. The method used in this research is descriptive qualitative with two data sources, primary data obtained from questionnaires filled out by 153 respondents and secondary data obtained from literature studies. The results showed that 50.33 percent of respondents prefer to shop for vegetables through e-commerce, and 51.63 percent think online vegetable shopping services are better than offline or conventional shopping. The majority of people choose to buy vegetables online through e-commerce because of concerns about the spread of the COVID-19 virus. However, vegetable purchasing behavior is still in the introduction stage. E-commerce plays a role in making it easier for people to get the needs of quality vegetables at competitive prices. Empowering farmers to produce high-quality products is very important in increasing consumer repurchase intentions and improving the welfare of farmers in Indonesia.
Design characteristics of showering aeration system
Authors: Roshan R. U. , Mohammad Tanveer , Roy Subha M. , Rajendran R.
Published: December 2021

The showering aeration system (SAS) was designed and its performance was evaluated by conducting the aeration experiments in a tank of dimension 2 × 4 × 1.5 m. Initially, the aeration experiments were conducted to optimize the radius of curvature of the SAS with different values, such as = 0, 5, 10, 15, and 20 mm, and maintain other geometric parameters, i.e. number of holes in the shower (); height of water fall (H); diameter of the shower hole (d); volume of water under aeration (V) and water flow rate (Q) as constants. The optimum radius of curvature () was found to be 10 mm. The aeration experiments were further conducted with four different non-dimensional geometric parameters such as the number of holes , the ratio of the height of water fall to the length of shower arm the ratio of the diameter of the hole to the length of shower arm and the ratio of the volume of water to the cube of the length of shower arm The Response Surface Methodology and Box–Behnken Design were used to optimize the non-dimensional geometric parameters of the SAS to maximize the Non-Dimensional Standard Aeration Efficiency. The result indicates that the maximum NDSAE of 16.98 × 106 was obtained from the SAS performance at = 80; = 2; = 4 and = 48.
Plantas Fungicidas Utilizadas em Comunidades Rurais da Região Sul do Piauí, Nordeste do Brasil
Authors: Sousa Santina Barbosa de , Barros Roseli Farias Melo de , Andrade Laíse de Holanda Cavalcanti , Lopes João Batista
Published: December 2021

Mediante estudo etnobotânico, objetivou-se listar plantas utilizadas para tratamento de infecções fúngicas em comunidades rurais do Nordeste do Brasil. Utilizou-se formulários semiestruturados, envolvendo 176 pessoas (99 do gênero feminino e 77 do masculino). Realizou-se turnês-guiadas para coletas e as exsicatas foram incorporadas ao Herbário Graziela Barroso (TEPB), da Universidade Federal do Piauí. Analisou-se os dados no NTSYSpc v.2.10t. Obteve-se 175 citações, identificando 36 espécies, distribuídas em 24 famílias e 35 gêneros. 84% são indicadas para tratamento de micoses em humanos, 10% em animais e 6% para fitopatógenos. Das plantas citadas, 54% são nativas, sendo a folha a parte mais usada (54%). As preparações foram cataplasma (55%), in natura (36%), decocção (5%) e a maceração (3%). Verificou-se que há diferença de conhecimento do número de espécies entre as comunidades, sendo Tamboril e Capim as mais similares.  O saber popular sobre plantas fungicidas tem potencial interesse para a medicina humana e veterinária.
Gongocompostagem: Técnica Sustentável para a Obtenção de Composto Orgânico para o Cultivo de Mudas de Brócolis
Authors: Antunes Luiz Fernando de Sousa , Vaz André Felipe de Sousa , Correia Maria Elizabeth Fernandes
Published: December 2021

A gongocompostagem é uma técnica ainda pouco conhecida no Brasil e no mundo, consistindo na atividade alimentar dos gongolos, os quais potencializam a fragmentação dos resíduos agrícolas e urbanos e através do acúmulo de seus péletes fecais ocorre a formação do composto orgânico pelo qual chamamos de gongocomposto. O objetivo deste trabalho foi avaliar a eficiência do gongocomposto na produção de mudas de brócolis. Os substratos utilizados foram os seguintes: gongocomposto obtido aos 180 dias de gongocompostagem e o substrato comercial Biomix®orgânico. Os substratos foram caracterizados quanto às suas propriedades físico-químicas, químicas e físicas. Foram avaliadas as massas secas da parte aérea e de raízes (g), altura de plantas (cm), número de folhas, notas do vigor de muda e estabilidade do torrão. O delineamento experimental adotado foi o inteiramente casualizado, com quatro repetições, cada qual constituída pela avaliação de 10 plantas retiradas aleatoriamente das bandejas aos 23 dias após a semeadura. O gongocomposto apresentou maior aporte de nutrientes e capacidade de retenção de água, além da menor densidade volumétrica, proporcionando assim a formação de mudas de brócolis com qualidade superior em relação às mudas desenvolvidas no substrato comercial Biomix®orgânico. O gongocomposto representa uma nova alternativa de substrato orgânico aos produtores, pois proporciona a obtenção de mudas mais vigorosas para o transplantio nos canteiros de produção.
Forensic Human Identification for Cutaneous Microbiome, a Brief Review
Authors: Novaes Natasha R.F. , Fensterseifer Isabel C. M. , Martins José L. R. , Silva Osmar N.
Published: December 2021

Forensic Science compounds many study areas in context of solving crimes, one of which is the forensic microbiology. Combined with genomic approaches, microbiology has shown strong performance in studies regarding the relationship between microorganisms present on human skin and environment. The Human Microbiome Project (HMP) has contributed significantly to characterization of microbial complexity and their connection to human being. The purpose of this work consists of a historical overview of scientific articles, demonstrating the growth and possibility of using skin microbiome in forensic identification. Studies about use of cutaneous microbiome in human identification, as well its forensic approaches, were looked into for writing of this review. Comparisons among cutaneous microbial communities and manipulated objects have been tested using 16S rRNA, as well as a thorough sequencing of the bacterial genome. From use of ecological measures of distance to genetic markers with nucleotide variants and predictive algorithms, research has shown promising results for advances in field of forensic identification. The development of metagenomic microbial panel markers, named hidSkinPlax for targeted sequencing has been designed and tested with great results. Research results show satisfactory potential in human identification by cutaneous microbiome and the possibility for contributive use in elucidating crimes.
A Água e o seu Entrelaçamento com a Sociedade Humana no Brasil
Authors: Césaro Silvana Gino Fernandes de
Published: December 2021

RESENHA DO LIVRO:Hanna Sonkajärvi & André Vasques Vital (orgs). A água no Brasil: Conflitos. Atores. Práticas. São Paulo: Alameda, 2019. 278p. ISBN: 9788579395949. Valor de Venda: R$ 48,00 (quarenta e oito reais) – alamedaeditorial.com.br
OBSERVATÓRIO DO AUDIOVISUAL POTIGUAR
Authors: Aires Janaine
Published: December 2021

Este artigo apresenta as diretrizes teóricas e metodológicas que orientam as ações do projeto de extensão Observatório do Audiovisual Potiguar, vinculado ao Departamento de Comunicação Social da Universidade Federal do Rio Grande do Norte. O projeto visa fornecer ao setor audiovisual e à sociedade ferramentas analíticas que auxiliem o desenvolvimento econômico, social e humano da região a partir da análise de sua produção audiovisual. Nosso objetivo é detalhar os pilares da proposta a fim de refletir sobre o papel social da extensão universitária na elaboração de ferramentas que auxiliem a formulação de política públicas, desenvolvimento de novas pesquisas e na difusão da memória e da cultura audiovisual.
Palavras-chave: observatório do audiovisual potiguar; políticas públicas; arranjo produtivo; extensão universitária.
DIAGNÓSTICO SITUACIONAL DOS PACIENTES DO COMPONENTE ESPECIALIZADO DE ASSISTÊNCIA FARMACÊUTICA DO PIAUÍ E ORIENTAÇÃO FARMACÊUTICA PARA USO RACIONAL DE MEDICAMENTOS
Authors: De Sousa Araújo Camila , De Oliveira Nery Neto José Arimatéia , Machado de Sousa Patrícia Caroline , Dos Santos Soares Joslanne , Portela Carneiro Sabrina Maria , Rocha e Silva Hilris
Published: December 2021

A Assistência Farmacêutica refere-se a um conjunto de orientações que devem garantir acesso aos medicamentos e sua utilização adequada. Nesse sentido, o presente artigo consiste na apresentação e discussão dos dados provenientes de um projeto que objetivou diagnosticar as condições clínicas de maior incidência em usuários do Componente Especializado de Assistência Farmacêutica do Piauí, de modo a propor direcionamentos que favoreçam ações de intervenção e orientação farmacêutica. O projeto contou com a colaboração de alunos extensionistas do curso de farmácia da Universidade Federal do Piauí, executando a proposta em quatro etapas: diagnóstico situacional, elaboração de material educativo, orientação farmacêutica e, por fim, campanhas de conscientização. Um bom índice de avaliação da aceitabilidade da população foi atingido, comprovando a relevância de projetos como esse.

Palavras-chave: Educação em farmácia; Cuidados farmacêuticos; Uso de medicamentos
PROJETO PENSAR:
Authors: Ferreira Targino da Cruz Melo Jacicleide , De Fátima Barbosa da Silva Cantalice Gizolene , Mariz de Oliveira Isabela
Published: December 2021

RESUMO

 

O presente texto tem como objetivo socializar resultados decorrentes de um projeto de extensão desenvolvido no ano de 2020, tendo como estratégia metodológica a realização de experiências de pensamento na perspectiva da Filosofia com Crianças. A ação atendeu alunos (crianças do Ensino Fundamental) de escolas da rede municipal de Caicó/RN. A equipe organizadora foi constituída por um professor da rede básica de ensino e cinco voluntários estudantes do curso de Pedagogia (CERES/UFRN). Foram realizadas oficinas com as crianças, cujos resultados apontaram a potencialidade da metodologia da Filosofia com criança para o desenvolvimento de habilidades de investigação, raciocínio, organização da informação e de tradução (diálogo) no processo de ensino e aprendizagem com crianças.

 

Palavras-chave: Pensar; Filosofia com Crianças; Linguagem; Extensão Universitária.
PROMOÇÃO DE INFORMAÇÃO A TRABALHADORES PARA O ENFRENTAMENTO DA COVID-19:
Authors: Alexandre André , Valverde Marques dos Santos Sérgio , Pimenta de Vasconcelos Neto Jony , Dos Reis Neiva Ana Flávia , Gonçalves da Silva Policardo
Published: December 2021

Com a pandemia do novo coronavírus muitas ações foram adotadas para combater sua disseminação, como o isolamento social. No entanto, muitos trabalhadores, considerados essenciais, continuaram nos seus postos de trabalhos, como supermercados, açougues, padarias, postos de combustíveis, farmácias, entre outros. Esses trabalhadores estão expostos ao risco de contaminação, uma vez que, a comunicação e a orientação sobre as formas de contágio ainda são limitadas. Neste sentido, relata-se aqui a experiência sobre um projeto de extensão que visou suprir a necessidade da promoção de informações e proteger tais trabalhadores em Passos-MG, oferecendo-lhes máscaras e fôlderes informativos, além de lives, enquadrando-se numa abordagem de saúde pública que se atentou para a saúde física e mental dos trabalhadores. Por fim, conclui-se que o projeto teve êxito em seus objetivos.

 

Palavras chave: COVID-19; Saúde do Trabalhador; Extensão Comunitária; Prevenção de Doenças
MULHER EM EVIDÊNCIA: TRADUÇÃO DO CONHECIMENTO CIENTÍFICO PARA MULHERES POR MEIO DE UMA REDE SOCIAL
Authors: Duarte Marinho Maria de Fátima , Nunes Ana Beatriz da Fonseca , Pereira Katia Maria , Pereira Ayrlla Vytória , Lira Jayara Mikarla de , Magalhães Adriana Gomes , Correia Grasiéla Nascimento
Published: December 2021

Durante a pandemia do novo coronavírus (SARS-CoV-2), as mulheres apresentaram dificuldade de acesso à saúde mediante ao risco de transmissão do vírus. Devido a essa necessidade, foi criado o projeto de extensão “Mulher em Evidência – Conhecimento além dos muros do Trairi" que usou o Instagram para disponibilizar conteúdos relacionados à Saúde da Mulher, com embasamento cientifico e linguagem acessível. Foram publicados 72 conteúdos, alcançando 27.325 pessoas e o tema mais curtido foi “O tabu da estética íntima” com 236 curtidas. Inicialmente os extensionistas relataram dificuldade para traduzir o conhecimento científico, entretanto este projeto de extensão alcançou o objetivo de disseminar ciência de qualidade e promover saúde para mulheres.

Palavras-chave: Saúde da Mulher; Infecções por Coronavírus; Rede Social.
Programa Hiperdia em tempos de pandemia pela Covid-19
Authors: Dos Santos de Souza Thais , Sales da Cruz Jamille , Carla Cerqueira dos Santos Vivian , Rodrigues Carvalho Ramona , Mary Andrade Teles Monteiro Nayara
Published: December 2021

Introdução: Com o advento da pandemia diversos impactos no processo de pensar, fazer e promover saúde. Neste cenário, diversos programas de assistência instituído na Atenção Básica (AB) tiveram suas atividades suspensas, dentre eles o HiperDia, rompendo assim, a integridade e longitudinalidade do processo do cuidar. Diante disso, há uma necessidade de retorno das atividades de modo integral, multidisciplinar e progressivo. Objetivo: Apresentar as vivências, percepções e inferências da equipe de residentes durante o processo de reintegração do programa HiperDia durante à Pandemia Covid-19. Metodologia: A presente obra trata-se de um estudo do tipo relato de experiência, de teor descritivo e abordagem qualitativa sobre uma atividade intervencionista de tempo indeterminado realizado por uma equipe multidisciplinar no município de Itabuna/BA. Resultado e discussão: Com o retorno das atividades, sensibilização da equipe e busca ativa dos usuários foi possível promover atividades de cunho assistencial, de promoção à saúde e prevenção de agravos. Neste contexto, duas atividades intervencionistas foram implementastes, sendo elas: O Mutirão do HiperDia e o Grupo Multiprofissional.  No decorrer destas consultas e acompanhamentos foi possível identificar e mitigar multiprofissionalmente fatores estressantes que culminavam no aumento dos valores pressóricos e glicêmicos. Além da ratificação do vínculo e fidelização deste para com a equipe Conclusão: Diante disso, conclui-se a imperatividade do retorno progressivo, integral, multidisciplinar da assistência, bem como, a necessidade da inserção de atividades de educação e saúde e ações intraterritórios visando a melhora da qualidade de vida biopsicossocial.
NEW FAUNISTICAL AND TAXONOMIC DATA ON ORIBATID MITES (ACARI, ORIBATIDA) FROM THE AFROTROPICAL REGION
Authors: Ermilov Sergey G. , Bąkowski Marek
Published: December 2021

The present study is based on oribatid mite materials collected in Ghana and Mozambique. A list of identified taxa, including 13 species from 12 genera and nine families, is provided. Of these, nine species, five genera and two families are recorded for the first time in the fauna of the above countries. One new species—Zetorchella ghanaensis sp. n. (Caloppiidae)—is described.
TWO NEW SPECIES OF THE FEATHER MITE GENUS TROUESSARTIA (ACARIFORMES: TROUESSARTIIDAE) FROM ROBINS AND CHATS (PASSERIFORMES: MUSCICAPIDAE) IN THE RUSSIAN FAR EAST
Authors: Mironov Sergey V.
Published: December 2021

Two new species of the feather mite genus Trouessartia (Analgoidea: Trouessartiidae) are described from passerine birds in Primorsky Krai (Russian Far East): Trouessartia calliope sp. n. from the Siberian Rubythroat Calliope calliope (Linnaeus) and T. larvivorae sp. n. from the Rufous-tailed Robin Larvivora sibilans (Swinhoe) (Passeriformes: Muscicapidae: Saxicolinae). Both new species are close to T. swidwiensis Jablonska, 1968 associated with nightingales of the genus Luscinia (Linnaeus) (Muscicapidae) in having the prohysteronotal and lobar parts of the hysteronotal shield not separated in males and in having setae h1 situated on large ovate non-sclerotized areas and in the absence of the external copulatory tube in females.
TWO NEW SPECIES AND A NEW RECORD OF SPATULAPHORUS (ACARI: PYGMEPHORIDAE) PHORETIC ON SCARAB BEETLES (COLEOPTERA: SCARABAEIDAE) FROM FRENCH GUIANA
Authors: Khaustov Alexander A. , Frolov Andrey V.
Published: December 2021

Two new species, Spatulaphorus dignus sp. n. and S. porosus sp. n. (Acari: Pygmephoridae), collected from scarab beetles Oxysternon durantoni and Coprophanaeus jasius, respectively, are described from French Guiana. Spatulaphorus brasiliensis Khaustov and Frolov, collected from the beetle Dichotomius borreus, is recorded from French Guiana for the first time. A key to the world species of the genus Spatulaphorus is also provided.
APTITUD COMBINATORIA DE LA VARIEDAD DE MAÍZ (Zea mays L.) Amiláceo PMD-638
Authors: Chura Chuquija Julian , García Pando Gilberto , Sevilla Panizo Ricardo
Published: December 2021

El objetivo fue estimar los efectos de la aptitud combinatoria general (ACG) y específica (ACE) de diez líneas S1 provenientes de la variedad PMD-638. El experimento fue conducido en la localidad de Jauja IRD-Sierra en la campaña 2016-2017. El diseño experimental fue bloques completos al azar, las variables estudiadas fueron rendimiento de grano (RG), floración masculina (FM) y femenina (FF), altura de planta (AP) y mazorca (AM). La ACG y ACE presentaron efectos significativos en todas las variables a excepción de FM en ACG. En RG la línea 9 presentó mayor efecto positivo con 0,66 y la línea 1 el mayor efecto negativo con -0,68, y en ACE la cruza 5x1 presentó mayor efecto negativo con -4,33. En días a FM la línea 9 presentó el mayor efecto para la ACG con 2,44 y en ACE mayor efecto presentó la cruza 6x5 con -9,95, En días a FF se presentó mayor efecto de ACG con la línea 5 (1,76) y en ACE la cruza 7x3 (4,82). En cuanto a AP y AM se tuvo mayor efecto de ACG con las líneas 9 y 10 con los siguientes valores -6,83 y 6,36 (AP) y -10.11 y 7.20 (AM). En la ACE para AP destacaron las cruzas 9x7 (-21,65) y 9x5 (20,66). En AM destacaron las cruzas 9x5 (22,40) y 7x3 (19,65).
IMPORTANCIA DE LA CARACTERIZACIÓN QUÍMICA DEL SUELO DE LAS ÁREAS VERDES MEDIANTE ESTADÍSTICO UNIVARIANTE Y ANÁLISIS DE CORRELACIÓN DE SPEARMAN EN LA UNIVERSIDAD PERUANA UNIÓN
Authors: Quispecuro-Huaman Jhon Cesar , Angel Rivas Diana Rocio , Cruz-Huaranga Milda Amparo
Published: December 2021

El propósito principal del estudio fue caracterizar químicamente las áreas verdes de la Universidad Peruana Unión para determinar la influencia de los distintos tipos de agua en la dinámica entre suelo receptor, soporte biológico y aportes químicos. Los parámetros analizados, comparados y correlacionados a partir de la extracción de muestras de suelo fueron pH, Nitrógeno Total, Materia Orgánica y Fósforo disponible. Seguidamente se utilizó el estadístico análisis de varianza univariante y el coeficiente de correlación de Spearman. El pH resultó ser el único parámetro significativo entre las áreas de estudio, se mostraron correlaciones altas entre Nitrógeno Total, Materia Orgánica y Fósforo Disponible. El tipo de agua para riego influencio en el comportamiento dinámico de las áreas verdes. Por consiguiente, el estudio resalta elegir de manera asertiva el tipo de agua para riego, gestionar los recursos hídricos tanto económicos y sostenibles con los que se cuenta (agua del rio, agua subterránea y agua de rio previamente tratada), formular, predecir y observar con precisión la dinámica química del suelo y evaluar zonas verdes extensas de naturaleza silvestre, forestal, rural o agrícola en el entorno inmediato o integrados en el espacio urbano de acuerdo al tipo de agua utilizada para riego.
Hydrogels for Modified-release Drug Delivery Systems
Authors: Zielińska Aleksandra , Eder Piotr , Rannier Lucas , Cardoso Juliana C. , Severino Patrícia , Silva Amélia M. , Souto Eliana B.
Published: December 2021

Hydrogels for the modified-release drug delivery systems are a continuously growing area of interest
for the pharmaceutical industry. According to the global market, the profit resulting from the use of polymers in
this area is projected to reach $31.4 million by 2027. This review discusses the recent advances in and perspectives
of hydrogel in drug delivery systems for oral, parenteral, nasal, topical, and ophthalmic delivery. The
search was conducted, in January 2021, in an extensive database to identify studies published from January
2010 to December 2020. We described the main characteristic of the polymers to obtain an ideal hydrogel for a
specific route of administration and the formulations. It was concluded that the hydrogels are useful to decrease
the number of doses and side effects, promote adhesion of patient, and enhance the bioavailability of the drugs,
thus improving the safety and efficacy of the treatment.
Recent Advances of Nanotechnology in the Diagnosis and Therapy of Triple-
Negative Breast Cancer (TNBC)
Authors: Kanugo Abhishek , Gautam Rupesh K. , Kamal Mohammad Amjad
Published: December 2021

Background:

The development of advanced treatment of triple-negative breast cancer (TNBC) is the utmost need of an era. TNBC is recognized as the most aggressive, metastatic cancer and the leading cause of mortality in females worldwide. The lack of expression of triple receptors namely, estrogen, progesterone, and human epidermal receptor 2 defined TNBC.

Objective:

The current review introduced the novel biomarkers such as miRNA and family, PD1, EGFR, VEGF, TILs, P53, AR and PI3K, etc. contributed significantly to the prognosis and diagnosis of TNBC. Once diagnosed, the advanced utilization approaches are available for TNBC because of the limitations of chemotherapy. Novel approaches include lipid-based (liposomes, SLN, NLC, and SNEDDS), polymer-based (micelle, nanoparticles, dendrimers, and quantum dots), advanced nanocarriers such as (exosomes, antibody and peptide-drug conjugates), and carbon-based nanocarriers (Carbon nanotubes, and graphene oxide). Lipid-based delivery is used for excellent carriers for hydrophobic drugs, biocompatibility, and lesser systemic toxicities than chemotherapeutic agents. Polymer-based approaches are preferred over lipids for providing longer circulation time, nanosize, high loading efficiency, high linking, avoiding the expulsion of drugs, targeted action, diagnostic and biosensing abilities. Advanced approaches like exosomes, conjugated moieties are preferred over polymeric for possessing potency, high penetrability, biomarkers, and avoiding the toxicity of tissues. Carbon-based gained wide applicability for their unique properties like a versatile carrier, prognostic, diagnostic, sensing, photodynamic, and photothermal characteristics.

Conclusion:

The survival rate can be increased by utilizing several kinds of biomarkers. The advanced approaches can also be significantly useful in the prognosis and theranostic of triple-negative breast cancer. One of the biggest successes in treating with nanotechnology-based approaches is the marked reduction of systemic toxicity with high therapeutic effectiveness compared with chemotherapy, surgery, etc. The requirements such as prompt diagnosis, longer circulation time, high efficiency, and high potency can be fulfilled with these nanocarriers.
Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives
Authors: Farghaly Thoraya A. , Dawood Kamal M.
Published: December 2021

Despite several reports and reviews addressing the biological significance of pyrazoles
and oxazines, no comprehensive work on the pyrazolo oxazine fused ring system has been published
so far. We report all biological evaluations on pyrazolo-oxazine derivatives in this mini-review to
provide an avenue for medicinal and pharmacological researchers to conduct further in-depth exploration.
Synthesis, Application, and Antibacterial Activity of New Direct Dyes based
on Chromene Derivatives
Authors: Mohamed Fatma A. , Ibrahim Hassan M. , Sheier Mahmoud B. , Reda Maysa M.
Published: December 2021

Aim:

This study aimed at synthesizing, analyzing, and utilizing two new direct dyes based on chromene derivatives as the chromophoric moiety in dyeing wool, silk, and cotton, with good color strength, light fastness, and other desirable features.

Background:

New direct dyes with antimicrobial activities for Gram-positive, Gram-negative bac-teria, and fungus are being developed. These dyes are used on cotton, silk, and wool materials, which have excellent light fastness, washing, rubbing, and perspiration fastness.

Methods:

All dyeing fabrics were tested for antibacterial activity. As a part of the experiment, parent structure 1 was previously synthesized. Then, diazotization and coupling reactions were used to prepare these dyes.

Results and Discussion:

P-Aminobenzenesulfonic acid (C1) and 4-Aminoazobenzene-3,4'-disul-fonic acid (C2) were diazotized in hydrochloric acid with sodium nitrite and then coupled with compound 1 in a molar ratio of 1:1 at 25 °C until the pH was fixed at 5. Finally, the monoazo and diazo direct dyes (D1 and D2) were prepared.

Conclusion:

Wool, silk, and cotton materials benefit from the increased antibacterial activities and dyeing qualities (exhaustion and fixing) of synthetic dyes. Furthermore, they offer excellent fast-ness qualities (light, rubbing, and perspiration).
Thymol and its Derivatives for Management of Phytopathogenic fungi of
Maize
Authors: Gaba Jyoti , Sharma Sunita , Kaur Harleen , Kaur Pardeep
Published: December 2021

Background:

Thymol is a bioactive compound having many pharmacological activities.

Objective:

The present study was carried out to evaluate the fungi toxic effects of thymol and derivatives
against phytopathogenic fungi of maize.

Method:

Thymol was derivatized to get formylated thymol, Mannich bases, and imine derivatives.
All the synthesized thymol derivatives were characterized by their physical and spectral properties.
Synthesized thymol derivatives were screened for their in vitro antifungal effects using poisoned
food technique against three maize pathogenic fungi, namely Fusarium moniliforme, Rhizoctonia
solani and Dreschlera maydis.

Results:

Thymol and formylated thymol showed promising results for control of D. maydis with
ED50 values less than standard carbendazim and comparable to standard mancozeb. These two
compounds were further evaluated for control of D. maydis causative maydis leaf blight disease on
maize plants grown in the field during the Kharif season (June to October) 2018.

Conclusion:

Thymol exhibited significant control of maydis leaf blight disease of maize and
emerged as a potential alternative to synthetic fungicides used in cereal crops.
Thalidomide Mitigates Apoptosis via Endoplasmic Reticulum Stress in
Diabetic Nephropathy
Authors: Zhang Hong-Xia , Yuan Jie , Li Rong-Shan
Published: December 2021

Background:

Previous studies have shown that endoplasmic reticulum (ER) stress is related to the apoptosis in the development of diabetic nephropathy (DN) and thalidomide (Thd) has renal-protective effects by suppressing inflammation and proliferation of MCs in DN. However, the effect of Thd on the apoptosis of MCs in DN remains largely unclear. The present research is designed to explore the effect of Thd on apoptosis in DN and the related mechanisms.

Objective:

The study is designed to examine the effect and mechanism of Thd on apoptosis in type 2 diabetic mice and high glucose (HG)-induced MCs.

Method:

We first evaluated the ER stress markers and apoptosis-related proteins with the treatment of Thd in type 2 diabetic mice and MCs in vitro under HG conditions. MTT assay was used to assess cell viability. Additionally, we evaluated the effect of Thd treatment upon MC apoptosis through flow cytometry. Real-time polymerase chain reaction (RT-PCR) and Western blot were performed to evaluate genes and protein expression related to ER stress and apoptosis.

Results:

The levels of blood urea BUN, CREA, Urine albumin, and UACR in diabetic mice were observed to be significantly reduced after 8 weeks of intervention with Thd. And also, there were upregulated glucose-regulated protein 78 (GRP78), Caspase-12, and downregulated B-cell lymphoma 2 (Bcl-2) in glomeruli of DN mice. In vitro, compared with the HG group, MC apoptosis reduced dramatically with Thd treatment along with upregulation of Bcl-2 and downregulation of Bax. At the same time, ER stress markers GRP78, C/EBP homologous protein (CHOP), and Caspase-12 were also mitigated following the Thd treatment.

Conclusion:

The present study indicates that Thd might reduce the ER stress in DN via downregulating GRP78, CHOP, and Caspase12 expressions, ultimately mitigating MCs apoptosis.
Review of Subdivision Schemes and their Applications
Authors: Shou Huahao , Liu Yan , Ji Kangsong
Published: December 2021

Background:

Methods of subdivision surfaces modeling and related technology research
have become a hot spot in the field of Computer-Aided Design (CAD) and Computer Graphics
(CG). In the early stage, research on subdivision curves and surfaces mainly focused on the relationship
between the points, thereby failing to satisfy the requirements of all geometric modeling. Considering
many geometric constraints is necessary to construct subdivision curves and surfaces for
achieving high-quality geometric modeling.

Objective:

This paper aims to summarize various subdivision schemes of subdivision curves and
surfaces, particularly in geometric constraints, such as points and normals. The findings help scholars
to grasp the current research status of subdivision curves and surfaces better and explore their
applications in geometric modeling.

Methods:

This paper reviews the theory and applications of subdivision schemes from four aspects.
We first discuss the background and key concept of subdivision schemes and then summarize the
classification of classical subdivision schemes. Next, we review the subdivision surfaces fitting and
summarize new subdivision schemes under geometric constraints. Applications of subdivision surfaces
are also discussed. Finally, this paper provides a brief summary and future application prospects.

Results:

Many research papers and patents on subdivision schemes are classified in this review paper.
Remarkable developments and improvements have been achieved in analytical computations
and practical applications.

Conclusion:

Our review shows that subdivision curves and surfaces are widely used in geometric
modeling. However, some topics need to be further studied. New subdivision schemes need to be
presented to meet the requirements of new practical applications.
A Mini-review on Nanostructured g-C3N4 Photocatalysts for Solar Fuel
Production
Authors: Akple Maxwell Selase , Takyi Gabriel Kwame Sipi
Published: December 2021

Graphitic carbon nitride (g-C3N4) is an important photocatalytic material that is receiving a lot
of research attention globally due to its favourable thermal and chemical stability as well as electronic
band structure. However, the photocatalytic performance of the bulk g-C3N4 is limited by fast recombination
of electron-hole pair and poor visible light-harvesting ability. Thus, different strategies, such as heterostructuring,
nanotuning, doping, etc., have been adopted to overcome the aforementioned challenges to
enhance the photocatalytic performance of g-C3N4. In recent times, various nanostructured g-C3N4 photocatalytic
materials with various tuned morphologies have been designed and fabricated in literature for
different photocatalytic activities. This mini-review summarized the progress development of nanostructured
g-C3N4 photocatalysts with various tuned morphologies for solar fuel generation. This article briefly
highlights the research status of various g-C3N4 with tuned morphologies and enhanced solar fuel generation
abilities. Finally, a conclusion and future research were also suggested, opening up new areas on g-
C3N4 photocatalysis.
Application of Metal-organic Framework Materials (MOFs) in the
Photocatalytic CO2 Reduction: A Mini-Review
Authors: Liu Yuanyuan , Jing Guolin , Zhang Huibo , Liu Yang , Yang Yihai , Xu Jianqi
Published: December 2021

In recent years, the effective use of CO2 has become one of the research hotspots worldwide to solve environmental pollution and energy shortage, whose excessive emission led to increasingly serious global environmental problems. Metal-organic frameworks (MOFs), with extraordinary specific surface areas, tunable surface chemistry, fast electron migration rate, large CO2 adsorption capacity, etc． are a new class of functional materials composed of metal ions/clusters and organic ligands, which have broad application potential in CO2 photocatalytic reduction. This paper systematically generalized the composition of the structure, discussed the methods of synthetics and expounded the photocatalytic properties and photocatalytic mechanism of MOFs. In addition, the application and research progress of MOFs functional materials in recent research are reviewed. The article also summarized challenges and prospects for the large-scale photocatalytic applications of MOFs catalysts. It guides the preparation of novel modified MOFs photocatalysts for high-efficiency applications in the field of CO2 reduction and photocatalytic degradation of dyes.
ATOPIC DERMATITIS: IMPROVING EARLY DETECTION AND PREVENTION MEASURES IN THE COMMUNITY SETTING
Authors:   Allergy-Immunology Division, Pediatric Department, Faculty of Medicine University of Brawijaya/dr. Saiful Anwar Hospital, Indonesia, Barlianto Wisnu , Wulandari Desy ,   Allergy-Immunology Division, Pediatric Department, Faculty of Medicine University of Brawijaya/dr. Saiful Anwar Hospital, Indonesia, Monica Charity ,   Pediatric Department, Faculty of Medicine University of Brawijaya/dr.Saiful Anwar Hospital, Indonesia, Humairok Nisak ,   Pediatric Department, Faculty of Medicine University of Brawijaya/dr.Saiful Anwar Hospital, Indonesia
Published: December 2021

Atopic dermatitis is a chronic inflammation of the skin characterized by disruption of the skin barrier and aberrations in the immune response. In general, atopic dermatitis can be affected by various complex interactions including genetics, diet, and stress. The lack of public attention to atopic dermatitis which often affects children is one of the factors for the increasing prevalence of atopic dermatitis. The purpose of this community service is to help the community understand the importance of early detection and allergy prevention efforts. Community service is carried out by holding online seminars that can be followed by the general public as well as direct consultations and discussions with pediatricians for allergy patients at the Department of Pediatrics at Dr. RSUD Dr. Saiful Anwar Malang. The total Immunoglobulin E level of the respondents was measured using the enzyme-linked immunosorbent assay method. The severity of the respondents was determined by calculating the SCORAD index. The results of early detection showed that 100% of respondents had intrinsic atopic dermatitis, 90% with mild severity and 10% with moderate severity. After being checked for allergies, the respondents received the appropriate supplements. Conclusion: By holding this community service activity, ordinary people become more aware of the importance of treating allergic diseases as early as possible because the incidence of atopic dermatitis can be reduced and the quality of life of patients can be improved. This outreach activity must be carried out continuously in the following years.
Hepatoprotective Activity of Helicteres isora Ethanol Extract Against Paracetamol-Induced Liver Injury in Mice
Authors: Giang Tran Thi Linh
Published: December 2021

Helicteres isora L. is a medicinal plant which is used in several diseases, such as snake-bite, dog-bite, diarrhoea and constipation in a new born baby, gastrointestinal disorders, diabetes, cancer, and infections. This plant has also been used in the management of liver damage through traditional medicine. However, the hepatoprotective activity of H. isora L. ethanolic extract has not been reported so much. The present work was carried to investigate the hepatoprotective effect of H. isora L. against paracetamol-induced liver injury in Swiss mice. Paracetamol (PCM) is widely used as an analgesic and antipyretic drug which at high dose can lead to undesirable side effects, such as hepatotoxicity. Paracetamol induce hepatotoxicity was evaluated by an increase (P<0.05) in AST and ALT serum activity. Paracetamol hepatotoxicity was also manifested by an increase in (P<0.05) lipid peroxidation and depletion of reduced glutathione (GSH) in liver tissue. Ethanol extract of H. isora L. (250, 500 and 1000 mg/kg bw/day) significantly restored the PCM-induced alterations in the biochemical activities of blood and liver tissues. The hepatoprotective effect of H. isora L. was also confirmed by the histopathological examination of liver tissue. Histopathological examination of liver sections in mice administered with 1000 mg/kg bw/day doses of the extract were perfectly protected almost similar to those of untreated mice. The results indicated the hepatoprotective nature of studied plants extract against paracetamol induced toxicity. Our study scientifically validates the folkloric claim as well as traditional uses of H. isora L. as hepatoactive medicine. The results of this study suggests a new direction in the treatment of liver disease in future.
Pharmacological Effect of Verapamil on Brain Oxidative Parameters and Mania-Like Behaviour in Paradoxical Sleep Deprived Mice
Authors: Eduviere Anthony T.
Published: December 2021

Although the implication of calcium signalling in the aetiology of anxiety remains elusive, drugs modulating calcium (like calcium channel blockers) have been discovered to be some worth beneficial as treatment option for anxiety related disorders. This study was therefore undertaken to assess probable ameliorative potential of verapamil against manic-like (stereotype behaviour) and anxiety-like symptoms in mice exposed to sleep deprivation. Mice were allotted into five treatment groups (n=5): group 1 and 2 received 10 mL/kg distilled water, groups 3 and 4 verapamil (25 and 50 mg/kg) while group 5 received astaxanthin (50 mg/kg) which served as the reference drug. Treatment was for 7 days and animals were sleep-deprived on the final 72 hours. Various behavioural tests to determine degree of stereotypical behaviour and locomotor activity were carried out. Anxiety test was done via the aid of a light/dark box and plus maze while stereotype behaviour was assess utilizing an open field box. Oxidative stress parameters; malondialdehyde and glutathione were assessed. Histopathological perturbations in the caudate putamen were also recorded. Data were subjected to ANOVA at α0.05. The results obtained suggest that verapamil significantly suppressed stereotyped behaviour and reduced the incidence of manic-like behaviour which was induced by paradoxical sleep deprivation. Verapamil also significantly restored antioxidant levels and protected against loss of caudate neurons. In conclusion, verapamil ameliorates manic-like symptoms and anxiety in mice derived of sleep, while protecting brain neurons against oxidative stress damage induced by sleep deprivation.