bluuebunny/crossref_metadata_2025 huggingface dataset:
Unified Model for Learning Style Recommendation
Authors: Ninrutsirikun Unhawa , Pal Debajyoti , Arpnikanondtand Chonlameth , Watanapa Bunthit
Published: July 2021

Studying computer programming requires not only an understanding of theories and concepts but also coding adeptness. Success in studying or conducting such a course is definitely a challenge. This paper proposes a systematic learning style recommendation. The model is designed to evaluate students’ attributes and ongoing or formative learning outcomes for suggesting the effective style-fit strategy that facilitates learners to enhance their learning performances in terms of knowledge and skill. A two-stage association analysis was designed and conducted on a dataset collected from IT major students who enrolled in the Introduction to Computer Programming course. The first stage of association rules is to analyze and discover important relationships amongst learning styles, students’ attribute, and learning performance. The second stage of moderation analysis is then applied to probe the moderation effect of the different learning preferences on the relationship between student attributes and learning achievement. Experiments expose many insights, for example, mathematics and logical thinking are powerful assets of success in computer programming study. Association rules can effectively identify associations of learning styles and the learning performance in terms of knowledge or skills. By moderation analysis, students in the “Excellent” cluster have a broad learning style than other students. Two types of significant moderators, the universal and specific, exemplify how lecturers can flexibly post style-fit teaching strategies for a class-wide and specific group, respectively.
Nursing Students' Perceptions of Peer Evaluation in Group Work at
Bethlehem University, Palestine
Authors: Saca-Hazboun Hanan , Abu-Nijmeh Amal , Maqboul Etaf
Published: July 2021

This study aimed to explore the perceptions and experiences of peer evaluation
(PE) in group work (GW) among nursing students at the Faculty of Nursing and
Health Sciences, Bethlehem University, Palestine in spring 2016. While previous
studies have examined the importance of PE in GW in a variety of disciplines in
higher education, researchers have not paid much attention to PE in the
assessment of nursing students in Palestine. A qualitative approach was used on
a sample population of third- and fourth-year nursing students (n = 70) at
Bethlehem University who had participated in PE in previous courses at least
three times. Results revealed that participation in GW promoted the students'
leadership skills, team spirit, self-confidence, and respect for others, while
significantly contributing to their professional growth. The results also
highlighted challenges to GW such as distributing assignments to groups and
providing clear specifications for the group leader's role. Results also showed
that the main challenges facing PE were the lack of objectivity, fairness,
anonymity, and clear evaluation criteria, as well as the limited items in the
evaluation forms. The study recommended the development of a faculty handbook
containing guidelines for GW and PE, conducting training sessions for students,
and encouraging all faculty members to use GW and PE routinely in their teaching
practices.
College-Based Transition Services' Impact on Self-Determination for Youth With Intellectual and Developmental Disabilities
Authors: Schillaci Rebecca S. , Parker Caroline E. , Grigal Meg , Paiewonsky Maria
Published: July 2021

Most youth in transition services with labels of intellectual and developmental disabilities (IDD) have poorer employment outcomes than their peers with other or without disabilities. One alternative approach to address this challenge provides youth with IDD access to transition services in the context of a college or university campus. College-based transition services (CBTS) provide students with IDD access to college courses, internships, and employment during their final 2 to 3 years of secondary education. A quasi-experimental design evaluation of one college-based transition services model, Think College Transition, found that, after controlling for student baseline scores, the college-based transition services had a significant effect on students' scores of self-determination at post-test. Implications for further refining the model are discussed.
Nesterov-accelerated adaptive momentum estimation-based wavefront distortion correction algorithm
Authors: Zhao Hui , An Jing , Yu Mengjie , Lv Diankai , Kuang Kaida , Zhang Tianqi
Published: July 2021

In order to improve the wavefront distortion correction performance of the classical stochastic parallel gradient descent (SPGD) algorithm, an optimized algorithm based on Nesterov-accelerated adaptive momentum estimation is proposed. It adopts a modified second-order momentum and a linearly varying gain coefficient to improve iterative stability. It integrates the Nesterov momentum term and the modified Adam optimizer to further improve the convergence speed, correct the direction of gradient descent in a timely fashion, and avoid falling into local extremum. Besides, to demonstrate the algorithm’s performance, a wavefront sensorless adaptive optics system model is established using a

6

×

6

element deformable mirror as wavefront corrector. Simulation results show that, compared with the SPGD algorithm, the proposed algorithm converges faster, and its Strehl ratio after convergence is nearly 6.25 times that of the SPGD algorithm. Also, the effectiveness and superiority of the proposed algorithm are verified by comparing with two existing optimization algorithms.
Active maintenance of a segmented mirror based on edge and tip sensing
Authors: Wang Bin , Dai Yichun , Jin Zhenyu , Yang Dehua , Xu Fangyu
Published: July 2021

An 8 m ring aperture segmented telescope is one of the important elements of the
Chinese Giant Solar Telescope (CGST) project. In addition, active
control of the primary mirror has become a key technology of the 8 m
ring solar telescope (8 m RST). Due to the particularity of the ring
aperture, the active maintenance of the segmented RST faces the
following problem: edge detection cannot provide enough information to
fulfil the closed-loop control. A scheme of using edge and tip
detection to complete the active maintenance of an 8 m RST has been
proposed. To study the feasibility and performance of edge detection
combined with tip detection, we built a workbench of a two-segmented
mirror and carried out an active maintenance analysis and experiment.
Two capacitive sensors were used to detect the edge height change
between the segments, and a Shack–Hartmann sensor was used to detect
the tip and tilt change of the segment. A stable mirror figure was
achieved during 100 min, and the mirror figure error was maintained at
18.94 nm. This work will provide reference for the implementation of
the active control for a segmented ring telescope and also give
evidence for the choice of the primary mirror of the CGST.
Monolithic all-silicon flat lens for broadband LWIR imaging
Authors: Kigner Orrin , Meem Monjurul , Baker Brian , Banerji Sourangsu , Hon Philip W. C. , Sensale-Rodriguez Berardi , Menon Rajesh
Published: July 2021

We designed, fabricated, and characterized a flat multi-level diffractive lens comprised of only silicon with

d
i
a
m
e
t
e
r

=

15.2

m
m

, focal

l
e
n
g
t
h

=

19

m
m

, numerical aperture of 0.371, and operating over the long-wave infrared (LWIR)

s
p
e
c
t
r
u
m

=

8

µ

m

to 14 µm. We experimentally demonstrated a field of view of 46°, depth of focus

>

5

m
m

, and wavelength-averaged Strehl ratio of 0.46. All of these metrics were comparable to those of a conventional refractive lens. The active device thickness is only 8 µm, and its weight (including the silicon substrate) is less than 0.2 g.
High precision dual-modulation differential terahertz ATR sensor for liquid measurements
Authors: Zheng Xiujun , Gevart Thomas , Gallot Guilhem
Published: July 2021

We describe a highly sensitive and stable quantum-cascade-laser-based attenuated total reflection (ATR) terahertz sensor for the detection of very low concentration solutions, using a dual-modulation differential approach and ATR geometry. This sensor offers a very high dynamic range and a long-term stability of 40 dB, which extends the potential of terahertz radiation for the analysis of liquid and biological samples. The performance is illustrated by measurements on standard solutions of ions, sugars, and proteins, for concentrations down to 1 µM.
SPP waveguide based on the Goos–Hänchen effect
Authors: Melentiev Pavel , Kuzin Arthur , Negrov Dmitry , Balykin Victor
Published: July 2021

We propose and realize a single-mode surface plasmon polariton (SPP) waveguide formed by two parallel grooves on the surface of a high-quality silver film. In the waveguide, the SPP wave undergoes the Goos–Hänchen shift of up to

0.77

⋅

λ

S
P
P

at each successive reflection, with the electric field of the SPP wave outside the metal, which significantly reduces the metal loss of the guided SPP wave. Using the waveguide, we demonstrate a complex on-chip optical circuit that includes (1) SPP plane wave excitation, (2) SPP plane wave focusing with a parabolic mirror, and (3) coupling of the focused SPP wave to the waveguide.
Color night vision ghost imaging based on a wavelet transform
Authors: Duan Deyang , Zhu Rong , Xia Yunjie
Published: July 2021

Night vision imaging is a technology that converts objects not visible to the human eye into visible images for night scenes and other low-light environments. However, conventional night vision imaging can directly produce only grayscale images. Here, we report a novel, to the best of our knowledge, color night vision imaging method based on a ghost imaging framework and optimized coincidence measurement based on wavelet transformation. An interesting phenomenon is that color night vision image can be directly produced by this new method. To our knowledge, this is the first direct color night vision imaging method without any conventional pseudocolor image fusion techniques. The experimental results show that this method can restore color very well for some objects. Moreover, the color of the night vision image is more natural and friendly to the human eye than that of conventional color night vision images. Due to the advantages of wavelet transforms, this method has high reconstruction ability for distorted signals.
Silicon photonics phase and intensity modulators for flat frequency comb generation
Authors: Deniel Lucas , Weckenmann Erwan , Pérez Galacho Diego , Lafforgue Christian , Monfray Stéphane , Alonso-Ramos Carlos , Bramerie Laurent , Boeuf Frédéric , Viven Laurent , Marris-Morini Delphine
Published: July 2021

Flat electro-optical frequency combs play an important role in a wide range of applications, such as metrology, spectroscopy, or microwave photonics. As a key technology for the integration of optical circuits, silicon photonics could benefit from on-chip, tunable, flat frequency comb generators. In this article, two different architectures based on silicon modulators are studied for this purpose. They rely on a time to frequency conversion principle to shape the comb envelope. Using a numerical model of the silicon traveling-wave phase modulators, their driving schemes are optimized before their performances are simulated and compared. A total of nine lines could be obtained within a 2 dB flatness, with a line-spacing ranging from 0.1 to 7 GHz. Since this tunability is a major asset of electro-optical frequency combs, the effect of segmenting the phase modulators is finally investigated, showing that the flat lines spacing could be extended up to 39 GHz by this method.
Background-free Detection of Mouse Antibodies on Mouse Tissue by Anti-isotype Secondary Antibodies
Authors: Mascadri Francesco , Ciccimarra Roberta , Bolognesi Maddalena M. , Stellari Fabio , Ravanetti Francesca , Cattoretti Giorgio
Published: July 2021

Immunodetection on mouse routinely processed tissue via antibodies raised in mice faces cross-reactivity of the secondary anti-mouse reagents with endogenous immunoglobulins, which permeate the tissue. Various solutions to this problem have been devised and include endogenous Ig block with anti-mouse Fab fragments or directly conjugated primary antibodies. Mouse isotype-specific antibodies, differently from reagents directed against both heavy and light chains, fail to detect endogenous Ig after fixation and embedding, while providing a clean and specific detection system for mouse antibodies on mouse routinely processed tissue.
DNA microarray analysis of Staphylococcus aureus from Nigeria and South Africa
Authors: Shittu Adebayo Osagie , Adesoji Tomiwa , Udo Edet Ekpenyong
Published: July 2021

Staphylococcus aureus is an important human pathogen with an arsenal of virulence factors and a propensity to acquire antibiotic resistance genes. The understanding of the global epidemiology of S. aureus through the use of various typing methods is important in the detection and tracking of novel and epidemic clones in countries and regions. However, detailed information on antibiotic resistance and virulence genes of S. aureus, and its population structure is still limited in Africa. In this study, S. aureus isolates collected in South Africa (n = 38) and Nigeria (n = 2) from 2001–2004 were characterized by spa typing and DNA microarray. The combination of these two methods classified the isolates into seven spa types and three clonal complexes (CCs) i.e. t064-CC8 (n = 17), t037-CC8 (n = 8), t1257-CC8 (n = 6), t045-CC5 (n = 5), t951-CC8 (n = 1), t2723-CC88 (n = 1), t6238-CC8 (n = 1), and untypeable-CC8 (n = 1). A high percentage agreement (>95%) and kappa coefficient (>0.60) was largely observed with antibiotic susceptibility testing and DNA microarray, indicating substantial agreement. Some antibiotic and virulence gene markers were associated with specific clones. The detection of the collagen-binding adhesion (cna) gene was unique for t037-CC8-MRSA while the enterotoxin gene cluster (egc) and staphylococcal complement inhibitor (scn) gene were identified with t045-CC5-MRSA. Moreover, the combination of genes encoding enterotoxins (entA, entB, entK, entQ) was noted with most of the CC8 isolates. The t045-CC5-MRSA clone was positive for the mercury resistance (mer) operon. DNA microarray provides information on antibiotic resistance and virulence gene determinants and can be a useful tool to identify gene markers for specific S. aureus clones in Africa.
An economic model of multi-level marketing
Authors: Reingewertz Yaniv
Published: July 2021

This paper offers an economic model of the operation of multi-level marketing (MLM) firms in competitive and non-competitive markets. The model takes a recursive approach to analyse decision making at the distributor level in order to understand basic issues in the MLM market and firm structure. Specifically, it is shown that under reasonable assumptions MLM firms will have a limited structure. In cases where commissions increase with the number of levels, MLM firms will include no more than six to nine levels in equilibrium. In cases of fixed commissions, market conditions dictate a cap on the number of distributors. These conditions imply a limited “multi-level” structure. They also imply that the revenues of the median distributor are mainly a result of direct sales and not a result of commissions. The model also suggests that MLM firms will only arise where marketing costs are substantial, and that it is primarily individuals with small outside offers who choose to become distributors. Finally, the model provides a formula that calculates market prices for a monopoly MLM firm.
Transcriptome and proteome of the corm, leaf and flower of Hypoxis hemerocallidea (African potato)
Authors: Tomescu Mihai-Silviu , Sooklal Selisha Ann , Ntsowe Thuto , Naicker Previn , Darnhofer Barbara , Archer Robert , Stoychev Stoyan , Swanevelder Dirk , Birner-Grünberger Ruth , Rumbold Karl
Published: July 2021

The corm of Hypoxis hemerocallidea, commonly known as the African potato, is used in traditional medicine to treat several medical conditions such as urinary infections, benign prostate hyperplasia, inflammatory conditions and testicular tumours. The metabolites contributing to the medicinal properties of H. hemerocallidea have been identified in several studies and, more recently, the active terpenoids of the plant were profiled. However, the biosynthetic pathways and the enzymes involved in the production of the terpene metabolites in H. hemerocallidea have not been characterised at a transcriptomic or proteomic level. In this study, total RNA extracted from the corm, leaf and flower tissues of H. hemerocallidea was sequenced on the Illumina HiSeq 2500 platform. A total of 143,549 transcripts were assembled de novo using Trinity and 107,131 transcripts were functionally annotated using the nr, GO, COG, KEGG and SWISS-PROT databases. Additionally, the proteome of the three tissues were sequenced using LC-MS/MS, revealing aspects of secondary metabolism and serving as data validation for the transcriptome. Functional annotation led to the identification of numerous terpene synthases such as nerolidol synthase, germacrene D synthase, and cycloartenol synthase amongst others. Annotations also revealed a transcript encoding the terpene synthase phytoalexin momilactone A synthase. Differential expression analysis using edgeR identified 946 transcripts differentially expressed between the three tissues and revealed that the leaf upregulates linalool synthase compared to the corm and the flower tissues. The transcriptome as well as the proteome of Hypoxis hemerocallidea presented here provide a foundation for future research.
Stress amelioration response of glycine betaine and Arbuscular mycorrhizal fungi in sorghum under Cr toxicity
Authors: Kumar Praveen
Published: July 2021

Chromium toxicity is a major problem in agricultural soils that negatively affects a plant’s metabolic activities. It reduces biochemical and antioxidant defence system’s activities. In search of the solution to this problem a two-year pot experiment (completely randomized design with three replications), in three genetically different varieties of sorghum (SSG 59–3, HJ 513 and HJ 541) under Cr toxicity (2 and 4 ppm) was conducted to determine the effect of glycine betaine (50 and 100mM) andArbuscular mycorrhizal fungi(AMF) on the antioxidant system (enzymesviz. superoxide dismutase, ascorbate peroxidase, catalase, glutathione reductase, peroxidase and metabolitesviz. glutathione, ascorbate, proline, β-carotene) along with Cr accumulation and indices of oxidative stress parameters (polyphenol oxidase, hydrogen peroxide and malondialdehyde) at two growth stages (vegetative and grain filling). According to results; Cr stress (2 & 4 ppm) increased its accumulation and indices of oxidative stresses significantly (p≤0.05) in all varieties of sorghum at both growth stages. However, soil application of glycine betaine (GB) and AMF decreased Cr accumulation and indices of oxidative stress by increasing antioxidant enzymes and metabolites activities at both growth stages in all varieties. The combination of 100mM GB with AMF was observed most significant (p≤0.05) in decreasing oxidative stress and improved the antioxidant system’s activities. The SSG 59–3 cultivar showed the lowest Cr accumulation (1.60 and 8.61 ppm), indices of oxidative stress and highest antioxidant system’s activity among these three cultivars at both growth stages. Thus, SSG 59–3 was found most tolerant cultivars followed by HJ 513 and then HJ 541. These findings suggest that both GB and AMF, either individually or combined can play a positive role to reduce oxidative stress and increased antioxidant attributes under Cr toxicity in sorghum.
Re-examining the effects of drought on intimate-partner violence
Authors: Cooper Matthew , Sandler Austin , Vitellozzi Sveva , Lee Yeyoung , Seymour Greg , Haile Beliyou , Azzari Carlo
Published: July 2021

Droughts are associated with several societal ills, especially in developing economies that rely on rainfed agriculture. Recently, researchers have begun to examine the effect of droughts on the risk of Intimate-Partner Violence (IPV), but so far this work has led to inconclusive results. For example, two large recent studies analyzed comparable data from multiple sub-Saharan African countries and drew opposite conclusions. We attempt to resolve this apparent paradox by replicating previous analyses with the largest data set yet assembled to study drought and IPV. Integrating the methods of previous studies and taking particular care to control for spatial autocorrelation, we find little association between drought and most forms of IPV, although we do find evidence of associations between drought and women’s partners exhibiting controlling behaviors. Moreover, we do not find significant heterogeneous effects based on wealth, employment, household drinking water sources, or urban-rural locality.
The effect of body weight-supported overground gait training for patients with Parkinson’s disease: A retrospective case-control observational study
Authors: Koyanagi Yasuki , Fukushi Isato , Nakamura Masatoshi , Suzuki Kouji , Oda Nobuhito , Aita Takashi , Seki Hareaki
Published: July 2021

Objective

To evaluate the effects of body weight-supported overground gait training (BWSOGT) on motor abilities, such as gait and balance, in patients with Parkinson’s disease (PD).

Design

Retrospective case-controlled observational study with a 4-week follow-up.

Setting

Inpatient rehabilitation.

Participants

We selected 37 of 68 patients with PD. Inclusion criteria were (1) Hoehn & Yahr stage II–IV, (2) no medication adjustment during the study period, (3) at least 1 week since last medication adjustment, and (4) ability to walk more than 10 meters on their own. Exclusion criteria were (1) cerebrovascular disease or other complications affecting movement, (2) difficulty in measurement, (3) early discharge, (4) medication change during the study, and (5) development of complications.

Interventions

Patients were divided into two groups. Patients in Group I underwent 20 minutes of BWSOGT with a mobile hoist in addition to the standard exercises; Group II performed 20 minutes of gait training in place of BWSOGT. In both groups, training was performed for a total of 15 times/4 weeks.

Main outcome measure(s)

Participants were evaluated using the Unified Parkinson’s Disease Rating Scale total, part II, and part III; 10-m walk test; velocity; stride length; 6-minute walk test; timed up and go test; Berg Balance Scale; and freezing of gait before and after the intervention.

Results

There were significant decreases in the Unified Parkinson’s Disease Rating Scale total, part II, and part III in both groups; however, 6-minute walk test, timed up and go test, and freezing of gait results only improved in Group I.

Conclusions

BWSOGT for patients with PD improves gait ability and dynamic balance more than standard gait training.
The early detection of immunoglobulins via optical-based lateral flow immunoassay platform in COVID-19 pandemic
Authors: Chen Pang-Yen , Ko Cheng-Hao , Wang C. Jason , Chen Chien-Wei , Chiu Wei-Huai , Hong Chitsung , Cheng Hao-Min , Wang I-Jen
Published: July 2021

The coronavirus disease (COVID-19) is the global public health challenge currently persisting at a grand scale. A method that meets the rapid quantitative detection of antibodies to assess the body’s immune response from natural COVID-19 illness or vaccines’ effects is urgently needed. In the present study, an attempt was made to integrate a newly designed spectrometer to the COVID-19 test strip procedure; this augmentation provides the quantitative capacity to a lateral flow immunoassay (LFIA). Optical interpretation of results by quantitative α index, rather than visual qualification, can be done quickly, in 5–10 minutes. The developed product was compared with several other serological IgM/IgG antibody reagents on the market by recruiting 111 participants suspected of having COVID-19 infection from March to May 2020 in a hospital. Taking RT-PCR as the diagnostic gold standard, the quantitative spectral LIFA platform could correctly detect all 12 COVID-19 patients. Concerning RT-PCR negative patients, all three antibody testing methods found positive cases. The optical-based platform exhibited the ability of early detection of immunoglobulins of RT-PCR negative patients. There was an apparent trend that elevation of IgM levels in the acute phase of infection; then IgG levels rose later. It exhibited the risk of a false-negative diagnosis of RT-PCR in COVID-19 testing. The significant detection ability of this new optical-based platform demonstrated clinical potential.
Seroprevalence of brucellosis and Q fever infections amongst pastoralists and their cattle herds in Sokoto State, Nigeria
Authors: Cadmus Simeon , Salam Samson Polycarp , Adesokan Hezekiah Kehinde , Akporube Kelechi , Ola-Daniel Fiyinfoluwa , Awosanya Emmanuel Jolaoluwa
Published: July 2021

Brucellosis and Q fever are neglected zoonoses of global health importance, with unknown true prevalence in occupationally vulnerable settings, partly due to misdiagnosis for other febrile conditions and poor access to primary health care. We examined the seroprevalence of these diseases and associated factors amongst pastoralists and their cattle in Sokoto State, a hub of cattle and pastoral populations in Nigeria. Serum samples randomly collected from 137 pastoralists and 366 cattle from 27 herds in three selected Local Government Areas (LGAs) in the state were analysed for antibodies to Brucella abortus using Rose Bengal Plate Test (RBT) and competitive Enzyme-Linked Immunosorbent Assay (cELISA) as well as antibodies to Coxiella burnetti using indirect ELISA. Consenting pastoralists’ knowledge, perception and practices about the diseases were assessed using a semi-structured questionnaire. Data were analysed using descriptive statistics and bivariate analysis at p ≤ 0.05 level of significance. Brucellosis adjusted individual seroprevalence were 0.83% (95%CI: 0.04–4.59%) and 0% among pastoralists; 2.28% (95%CI: 1.16–4.43%) and 5.70% (95%CI: 3.68–8.74%) in cattle by RBT and cELISA, respectively. Adjusted herd-level seroprevalence for brucellosis were 23.20% (95%CI: 11.07–42.54%) and 42.00% (95%CI: 25.27–61.11%) by RBT and cELISA, respectively. For Q fever, higher seroprevalence of 62.57% (95%CI: 54.04–70.46%) and 2.98% (95%CI: 1.57–5.58%) were recorded amongst the pastoralists and their cattle, respectively. with adjusted herd-level seroprevalence of 40.36% (95%CI: 22.57–63.17%). The LGAs of sampling were significantly (OR: 0.2; 95%CI: 0.02–1.00) associated with Q fever infection, though marginal. The majority of the pastoralists had poor knowledge, perception and practices towards the diseases. This is the first study establishing the presence of brucellosis and Q fever at the human-animal interface in Sokoto State, Nigeria. The pastoralists’ poor knowledge, perception and practices about these diseases are worrisome and are important factors for consideration in disease control.
Prevalence of nevi, atypical nevi, and lentigines in relation to tobacco smoking
Authors: Sadoghi Birgit , Schmid-Zalaudek Karin , Zalaudek Iris , Fink-Puches Regina , Niederkorn Anna , Wolf Ingrid , Rohrer Peter , Richtig Erika
Published: July 2021

Background

Melanocytic nevi have a complex evolution influenced by several endogenous and exogenous factors and are known risk factors for malignant melanoma. Interestingly, tobacco use seems to be inversely associated with melanoma risk. However, the association between tobacco use and nevi and lentigines has not yet been evaluated.

Methods

We investigated the prevalence of nevi, atypical nevi, and lentigines in relation to tobacco smoking in a cohort of 59 smokers and 60 age- and sex-matched nonsmokers, using a questionnaire and performing a total body skin examination by experts.

Results

No significant differences were detected between smokers and nonsmokers in the numbers of nevi, atypical nevi, and lentigines in sun-exposed areas (p = 0.966, 0.326, and 0.241, respectively) and in non-sun-exposed areas (p = 0.095, 0.351, and 0.546, respectively).

Conclusion

Our results revealed no significant differences in the prevalence of nevi, atypical nevi, and lentigines between smokers and nonsmokers in sun-exposed and non-sun-exposed areas.
Differentiating iron-loading anemias using a newly developed and analytically validated ELISA for human serum erythroferrone
Authors: Diepeveen Laura , Roelofs Rian , Grebenchtchikov Nicolai , van Swelm Rachel , Kautz Leon , Swinkels Dorine
Published: July 2021

Erythroferrone (ERFE), the erythroid regulator of iron metabolism, inhibits hepcidin to increase iron availability for erythropoiesis. ERFE plays a pathological role during ineffective erythropoiesis as occurs in X-linked sideroblastic anemia (XLSA) and β-thalassemia. Its measurement might serve as an indicator of severity for these diseases. However, for reliable quantification of ERFE analytical characterization is indispensable to determine the assay’s limitations and define proper methodology. We developed a sandwich ELISA for human serum ERFE using polyclonal antibodies and report its extensive analytical validation. This new assay showed, for the first time, the differentiation of XLSA and β-thalassemia major patients from healthy controls (p = 0.03) and from each other (p<0.01), showing the assay provides biological plausible results. Despite poor dilution linearity, parallelism and recovery in patient serum matrix, which indicated presence of a matrix effect and/or different immunoreactivity of the antibodies to the recombinant standard and the endogenous analyte, our assay correlated well with two other existing ERFE ELISAs (both R2 = 0.83). Nevertheless, employment of one optimal dilution of all serum samples is warranted to obtain reliable results. When adequately performed, the assay can be used to further unravel the human erythropoiesis-hepcidin-iron axis in various disorders and assess the added diagnostic value of ERFE.
Effect of insulin treatment on pulsatility ratio and resistance index of the retinal artery in patients with type 2 diabetes
Authors: Omae Tsuneaki , Song Youngseok , Yoshioka Takafumi , Tani Tomofumi , Yoshida Akitoshi
Published: July 2021

This study aimed to evaluate whether long-term insulin treatment is associated with abnormalities in retinal circulation in type 2 diabetic patients. We evaluated 19 eyes of nondiabetic individuals and 68 eyes of type 2 diabetic patients. The eyes of diabetic patients were classified into two groups according to the presence or absence of long-term insulin therapy. We used a Doppler optical coherence tomography flowmeter to measure diameter, velocity, and blood flow in the major temporal retinal artery. The pulsatility ratio (PR) and resistance index (RI), indices of vascular rigidity, were calculated from the blood velocity profile. PR and RI were significantly elevated in type 2 diabetic patients compared with nondiabetic subjects (P < 0.05). In type 2 diabetes patients, PR and RI were significantly higher in patients receiving long-term insulin treatment than in those without (P < 0.01). There was a significant difference in velocity (P < 0.05), but not diameter and blood flow, between nondiabetic subjects and type 2 diabetes patients. No significant difference in diameter, velocity, or blood flow was observed between the groups with and without long-term insulin treatment. Long-term insulin treatment can affect PR and RI, which might be associated with vascular rigidity of the retinal artery in patients with type 2 diabetes.
Cambio cultural y lectura. Hacia una nueva cultura lectora
Authors: Bernal Guerrero Antonio
Published: July 2021

Las limitaciones de las prácticas lectoras actuales quizás puedan apreciarse mejor en el seno de los cambios culturales que se producen con el paso de la sociedad moderna a la posmoderna. Estas tecnologías de la vida cotidiana están cambiando pro- fundamente nuestras formas de trabajar, de relacionarnos, de vivir. La sacralización del libro propia de la modernidad pierde sentido en el mundo audiovisual actual, donde multitud de jóvenes descifran reglas y desarrollan nuevas destrezas usando los nuevos artefactos tecnológicos. La ignorancia de la vigencia de las nuevas prácticas culturales conduce al desencuentro cultural intergeneracional, que tanto daño está causando en los sistemas escolares. Las condiciones de las sociedades de la información reclaman un nuevo contexto para la cultura lectora, emergiendo nuevas posibilidades formativas.
Portal global de educación ambiental. Una experiencia de innovación educativa en el espacio virtual de formación
Authors: Barrón Ruiz Ángela , Muñoz Rodríguez José Manuel , Pérez Sánchez Lourdes
Published: July 2021

En este trabajo se presenta una experiencia de innovación educativa que pre- tende profundizar en la investigación de formas y usos de las nuevas tecnologías en cuanto que espacio para el desarrollo y la implementación de la Educación Ambiental. Los autores, tras exponer el punto de partida y marco conceptual en el que se sustenta la experiencia, y tras un breve repaso de lo que supone relacionar Educación Ambiental e Internet, describen la experiencia: objetivos, contenidos, fases, metodología, evaluación y resultados. Se trata del diseño e implementación de una Web, compatible con la for- mación en espacios virtuales, cuyo objetivo es mejorar la difusión de información y conocimiento de recursos, experiencias, investigaciones, servicios y compromisos para el avance de la Educación Ambiental en un ámbito concreto así como la formación y colaboración entre Educadores Ambientales. Concluyen el trabajo presentando una reflexión crítica en torno a una serie de temas que amplían, en base a esta experiencia, la investigación y la práctica educativo-ambiental.
Juegos serios y entrenamiento en la sociedad digital
Authors: Marcano Beatriz
Published: July 2021

En este artículo, basado en una investigación documental, se expone la función del juego como herramienta de aprendizaje de conductas y actitudes sociales y prácticas, señalando que este rol lo desempeñan en la actualidad los videojuegos como productos tecnológicos de la sociedad digital. Se destaca la modalidad de videojuegos denominada: Juegos Serios, los cuales se caracterizan por estar diseñados especialmente con fines formativos (educativos, entrenamiento e información). Se describen los rasgos principales de los juegos serios, así como las áreas en las que más se usan, que son: la militar, la educativa, la empresarial, la gubernamental y la política. Se comentan, además, variados ejemplos que incluyen simulaciones, videojuegos y juegos de realidad alternativa. Finalmente se destaca la efectividad que se logra con la implementación de los juegos serios por la flexibilidad y adaptación a los usuarios y el gran alcance que tienen en las poblaciones a las que se dirigen.
El rol de género en los videojuegos
Authors: Sauquillo Mateo Piedad , Ros Ros Concepción , Bellver Moreno Mª Carmen
Published: July 2021

La educación para la igualdad requiere de la implicación de todas y cada una de las agencias que participan de este proceso. En este trabajo hemos querido conocer en qué medida los videojuegos más vendidos y utilizados por la población infantil y juvenil transmiten contenidos que contribuyen a su educación para la igualdad o, por el contrario, la dificultan. Para ello hemos analizado el contenido de los diez videojuegos más jugados por menores y adolescente, atendiendo a los valores y disvalores que transmiten, centrando nuestra atención en la representación de modelos de mujer y roles de género. Por último, hemos tratado de establecer una serie de conclusiones y orientaciones pedagógicas, dejando abierta la posibilidad de desarrollar futuras investigaciones en esta línea.
Capacitaciones autónomas indígenas - Respuesta a la política asimiladora nacional. El ejemplo de los Wixaritar de México
Authors: Goschenhofer Christina , De La Cruz Carrillo Santos , Chávez Reyes Carlos
Published: July 2021

Las condiciones de vida de los pueblos indígenas en México están terminadas por la política asimiladora del gobierno mexicano, entre otros. Bajo el llamado Indigenismo, se lleva acabo programas oficiales para la asimilación y aculturalización de los pueblos indígenas. Rechazando esa negación de autodeterminación indígena, los indígenas mexicanos reivindican el reconocimiento y la implementación de sus derechos y ponen esfuerzo en llevar a la práctica formas locales de autonomía. En el debate por la autonomía indígena, el sector de la educación representa punto nodal de gran importancia : se reclaman influencia sobre ello tanto los programas gubernamentales de integración como los indígenas en el curso del establecimiento de una educación indígena autodeterminada. También los Wixaritari, pueblo de la Sierra Madre Occidental, ellos mismos, “desde abajo”, y de manera propia, responden al asunto por una educación indígena–autónoma. Teniendo la base en las experiencias concretas de la Comunidad Indígena Autónoma de Bancos de San Hipólito, en ese artículo presentamos el concepto de las capacitaciones y discutimos su papel para un desarrollo autoterminado.
Mujer e inmigración: educación en las aulas
Authors: Maya Frades Valentina
Published: July 2021

En este artículo recogemos lo que ha supuesto en la última década el proceso de la inmigración analizando las estadísticas del alumnado no universitario en el sistema educativo español. El objetivo principal es conocer las diferencias de género en función de la nacionalidad de l@s alumn@s y teniendo en cuenta los diversos niveles educativos. Para ello, se ha hecho un análisis completo de la estadística de alumn@s en el curso 2000-2001 y 2005-06, de los que hemos obtenido un mapa bastante matizado y completo de la presencia de niñas y jóvenes hijas de inmigrantes en el sistema escolar español.
El profesor – tutor en una experiencia docente universita-ria online – presencial
Authors: Ugarte Carolina , Naval Concepción
Published: July 2021

En estos últimos años, en el marco del Espacio Europeo de Educación Superior, hemos sido testigos de un creciente interés por mejorar las competencias de los universitarios. También desde el entorno profesional se pide a la Universidad que proporcione posibilidades formativas que ayuden a los alumnos a desenvolverse en la vida profesional. Con este contexto teórico de referencia, ofrecemos una experiencia en la que estamos implicados en la docencia universitaria. Se trata de la asignatura de libre elección: Formación en competencias profesionales (I y II). En este artículo, se comenta la metodología seguida en esta asignatura, prestando especial atención a uno de sus elementos clave: el profesor-tutor.
As estratégias de comunicação da Netflix brasil e o engajamento do público nas redes sociais da Internet
Authors: Vernizi Gonçalves Mariana , Pelinson Fabiana
Published: July 2021

Este artigo objetiva apresentar as estratégias de comunicação digital da Netflix Brasil em três redes sociais da Internet – Facebook, Instagram e Twitter – e caracterizar o engajamento dos usuários com tais estratégias. Para isso, realiza-se uma pesquisa quantitativa-qualitativa, de cunho descritivo e explicativo, ao analisar 169 postagens da Netflix Brasil. A discussão dos dados é orientada pela Análise de Conteúdo e pelo Fluxograma de Engajamento. Os resultados evidenciam o uso de seis estratégias comunicacionais, por ordem de frequência: informações sobre lançamentos, informações sobre a empresa, abordagem de humor, utilização de memes, busca por interação e ativismo social. Além disso, o engajamento dos seguidores se caracteriza entre os níveis de envolvimento e interação, com nuances de intimidade.
Apontamentos sobre a construção mítica e publicitária das atletas da seleção brasileira em peças veiculadas durante a Copa do Mundo de futebol feminino 2019
Authors: Weyh Fernanda , Barth Maurício , Roese Sanfelice Gustavo
Published: July 2021

Este trabalho tem como objetivo analisar a construção mítica e publicitária das atletas da Seleção Brasileira em peças veiculadas durante a Copa do Mundo de Futebol Feminino 2019. Para tanto, foram selecionados, a fim de cumprir o objetivo proposto, os comerciais: (1) Marta #ElaÉNúmero 1, (2) Andressa Alves’ Story e (3) Copa do Mundo Feminina da FIFA, analisados através da Retórica da Imagem de Barthes (1990). Ao fim do estudo, constatou-se que as peças selecionadas potencializaram a criação e recriação de atletas-mito, despertando a atenção nos comerciais publicitários estudados através de pontos como talento, superação e habilidade e, até mesmo, à “alegria” das jogadoras – remetendo à brasilidade. Concluiu-se, ainda, que o atleta-mito personifica, portanto, a figura com a qual muitas pessoas se identificam, sendo considerado um modelo exemplar para a humanidade, com seus desafios, dificuldades e sofrimentos, com suas vitórias e derrotas; enfim, com a luta pela sua história.
La polarización de la opinión pública europea ante la inmigración
Authors: Goya García de Paor Caoimhe
Published: July 2021

A lo largo de la última década, Europa se ha enfrentado a una profunda recesión económica seguida de un aumento del número de ataques terroristas como consecuencia de los conflictos en Oriente Medio y a una grave crisis migratoria que se caracteriza por la llegada masiva de refugiados e inmigrantes al Sur de Europa. Todo ello ha generado un sentimiento cada vez más generalizado de recelo hacia la globalización, manifestándose en un avivado llamamiento a la primacía de la soberanía del Estado y al cierre de fronteras.

En este contexto, existe una enorme polarización en la opinión pública en torno a cómo debe tratarse el tema de la inmigración. Mientras que en Estados como Irlanda el porcentaje de la población favorable a la inmigración se fija en un 76 por ciento, en otros Estados tales como la República Checa, la actitud positiva ante la inmigración se manifiesta en un 14,58 por ciento de la población. Esta discordancia de opinión es un reflejo de la crisis de valores que está sufriendo la Unión Europea. Mientras que un sector de la población europea quiere seguir manteniéndose fiel a los valores iniciales sobre los que se fundó la UE, otro amplio sector considera necesario reexaminar nuestros valores en pro de la economía, la identidad social y la seguridad de los ciudadanos.
Решение связанной нестационарной задачи термоупругости для жесткозакрепленной многослойной круглой пластины методом конечных интегральных преобразований
Authors: Шляхин Дмитрий Аверкиевич , Shlyakhin Dmitriy Averkievich , Кусаева Жанслу Маратовна , Kusaeva Zhanslu Maratovna
Published: July 2021

Построено новое замкнутое решение
осесимметричной нестационарной задачи для жесткозакрепленной круглой
многослойной пластины в случае изменения температуры на ее верхней лицевой
поверхности (граничные условия 1-го рода) и учета конвекционного
теплообмена нижней лицевой поверхности с окружающей средой (граничные
условия 3-го рода).
Математическая формулировка рассматриваемой задачи включает линейные
уравнения равновесия и теплопроводности (классическая теория) в пространственной постановке в предположении, что при анализе работы исследуемой конструкции можно пренебречь ее инерционными характеристиками.
При этом используется полуобратный метод решения, связанный с заданием на
цилиндрической поверхности конструкции касательных напряжений,
которые позволяют с заданной точностью удовлетворить условия жесткого закрепления пластины.
При построении общего решения нестационарной задачи, описываемой системой
линейных связанных несамосопряженных уравнений в частных производных,
используется математический аппарат разделения переменных в виде конечных
интегральных преобразований Фурье-Бесселя и обобщенного биортогонального
преобразования. Особенностью данного решения является применение конечного интегрального преобразования,
основанного на многокомпонентном соотношении собственных вектор-функций
двух однородных краевых задач с выделением сопряженного оператора,
позволяющего осуществить решение несамосопряженных линейных задач
математической физики. Данное преобразование является наиболее эффективным
методом исследования подобных краевых задач.
Построенные расчетные соотношения дают возможность определить
напряженно-деформированное состояние и характер распределения
температурного поля в жесткозакрепленной круглой многослойной пластине при
произвольном по времени и радиальной координате внешнем температурном
воздействии. Кроме того, численные результаты расчета позволяют
проанализировать эффект связанности термоупругих полей, который приводит к существенному увеличению нормальных напряжений по сравнению с решением аналогичных задач в несвязанной постановке.
Равновесие жестко закрепленной на внешней поверхности полой трансверсально-изотропной толстостенной сферы, находящейся под действием равномерного внутреннего давления и гравитационных сил
Authors: Фукалов Антон Александрович , Fukalov Anton Alexandrovich , Зайцев Алексей Вячеславович , Zaitsev Alexey Vyacheslavovich , Соколкин Юрий Викторович , Sokolkin Yuriy Viktorovich , Баяндин Юрий Витальевич , Bayandin Yurii Vital'evich
Published: July 2021

С использованием разложения компонент вектора перемещений по окружной и радиальной координатам в ряды по полиномам Лежандра и обобщенных степенных рядов получено точное аналитическое решение задачи о равновесии жестко закрепленного на внешней поверхности толстостенного трансверсально-изотропного
центрально-симметричного полого тела, которое находится под действием равномерного внутреннего давления и гравитационных сил.
В качестве примера использования полученного аналитического решения проанализировано влияние массовых сил на характер распределения независимых инвариантов тензора напряжений в поперечном сечении тяжелой железобетонной сферы, внутренняя поверхность которой свободна от внутреннего давления.
На основе многокритериального подхода, описывающего различные механизмы исчерпания несущей способности (от растяжения или сжатия в радиальном и окружном направлениях и межслойного сдвига), определены области тяжелой железобетонной сферы, в которых может быть инициировано разрушение.
Проведено качественное и количественное сравнение полей напряжений в точках поперечных сечений толстостенных тяжелых сфер с результатами численного решения той же задачи в осесимметричной и трехмерной постановках в конечноэлементных пакетах ANSYS 13.0 и ABAQUS 6.11. Оба пакета продемонстрировали минимальное отклонение численно определенных значений инвариантов напряжений от аналитического решения в осесимметричной постановке и различие с сопоставимой погрешностью - в трехмерной.
В последнем случае представление численных результатов для напряжений и деформаций в компонентной форме привело к неожиданному эффекту - появлению существенных ошибок по сравнению с точным аналитическим решением.
Для исключения обнаруженных при определении напряженно-деформированного состояния ошибок, которые обусловлены только особенностями определения сферической системы координат в конечноэлементных пакетах ANSYS 13.0 и ABAQUS 6.11, необходимо использовать представление полученных результатов в инвариантном виде.