bluuebunny/crossref_metadata_2025 huggingface dataset:
Phylogenetic Diversity of Microorganisms from the Abakan Arzhan Thermal Spring: Potential Producers of Microbial Energy
Authors: Dmitrieva Anastasia , Faskhutdinova Elizaveta , Drozdova Margarita , Kutuzov Sergei , Proskuryakova Larisa
Published: October 2022

Microbial energy is a promising area of innovative development in bio- and nanotechnology. Recent studies have revealed that microbial communities of thermal springs have excellent implementation prospects in this area. The present article introduces the microbial diversity of the Abakan Arzhan thermal spring and their isolates that are potentially applicable in microbial electricity synthesis.

The research featured microbial isolates obtained from a microbiota analysis of water and slit samples from the Abakan Arzhan thermal spring. The study involved a metagenomic analysis of the microbial community, as well as such molecular biology methods as nucleic acid extraction, PCR, sequencing, phylogenetic, and bioinformatic analysis. The Silva library was used to compare 16S RNA sequences

Firmicutes, Bacteroides, and Proteobacteria proved to be the dominant phylotypes for water samples, while Firmicutes, Thermomonas, Gammaproteobacteria, and Proteobacteria were the dominant phylotypes for slit samples. The analysis of minor phylotypes confirmed the presence of Geobacter and Shewanella in the samples. The total number of obtained enrichment cultures was nine. Two types of resistant colonies were discovered during the isolation of extremophilic iron-reducing isolates. The samples were grown on a medium containing iron (III) acetate and iron (III) nitrate, and the isolates appeared to be in the process of Fe(III) reduction. The isolates showed an intense iron recovery of 409 and 407 µg/mL after 72 h of cultivation.

The study confirmed the ability of the acquired isolates to reduce iron, making them a priority for future microbial energy research. The isolates belonged to the Shewanella algae and Geobacter sulfurreducens species, as determined by 16S RNA morphology and phylogenetic analyses.
Identifying Bioactive Peptides from Poultry By-Products
Authors: Voroshilin Roman , Kurbanova Marina , Yustratov Vladimir , Larichev Timothy
Published: October 2022

Bioactive peptides derived from food proteins are becoming increasingly popular ingredients due to their beneficial effect on the immune system and other functional properties. We aimed to develop a technology for obtaining peptides from poultry by-products and identify their bioactivity.

Pepsin was the main reagent for the in vitro enzymatic hydrolysis. Specialized equipment and methods were used to determine the key indicators. The molecular weight and bioactivity of the resulting peptides were calculated by using the Peptide Mass Calculator and PeptideRanker online resources.

First, we developed a flow chart for obtaining bioactive peptides and produced hydrolysates from poultry by-products. The hydrolysates had identical physicochemical parameters, with no significant differences. The molecular weight distribution revealed that most protein fractions were represented by peptides with a molecular weight below 20 kDa. Then, we evaluated the bioactivity of the peptides. The hydrolysate obtained using pepsin with an activity of 30 units per 100 g of material showed higher bioactivity in the FD peptides (0.922094). The hydrolysate obtained using pepsin with an activity of 45 units per 100 g of material had greater bioactive properties in the CYG p eptides (0.947378).

Based on the results, we designed a flow chart for obtaining hydrolysates from poultry by-products and evaluated the bioactive properties of the peptides obtained. For further work, these properties should be confirmed by in vitro experiments to determine the reliability of our data and identify specific bioactive properties of the peptides.
Depression: Does water matter?
Authors: Shi Hongxu
Published: October 2022

Subjective well-being is a metric for assessing the effectiveness of public policy. However, the relationship between depression, an important indicator of subjective well-being, and access to clean water (ACW) has received scant attention. This study investigates the effect of ACW on depression using the 2014–2018 waves of the China Family Panel Studies (CFPS). Using ordinary least squares (OLS) two-way fixed effects (FE) estimation, the results indicate that ACW leads to lower levels of depression. The ACW–depression relationship is mediated by individual self-reported health and household food expenditure, but the mechanism varies across subsamples, as determined by structural equation modelling of the underlying mechanisms. The results of the heterogeneity analysis demonstrated that the total effect of the absence of ACW on depression is mitigated when rural migrants reside in cities, and that the effect disappears entirely when the migrant has an urban hukou. These findings demonstrate the negative impact of urban–rural disparities and hukou issues on mental health.
Investigating socio-economic factors underlying urban consumers' willingness to pay extra for drinking water
Authors: Nouri-Khajebelagh Rassol , Khaledian Mohammadreza , Kavoosi-Kalashami Mohammad
Published: October 2022

The purpose of this study is to investigate the impact of economic and social factors on increasing public participation in the urban drinking water sector to develop a suitable plan for the coming years due to the growing population. The research instrument is a researcher-made questionnaire whose validity and reliability were confirmed. Then, 1,230 questionnaires were distributed among the citizens of Ardabil, Iran. A two-stage Heckman approach was used to estimate the valuation model. The results showed that the education, age, water health concern, income, household cost, household size and water quality satisfaction had a significant role in the amount of willingness to pay extra (WTP). The results showed that the variable age, income and water quality have a positive effect on WTP; with increases in the age, income and the water quality, WTP increases. However, in contrast to the water bill, concerns about the health of water and children have a negative effect on WTP. The results showed that the government could increase their tendency to participate with the government by informing people to water value and improve the quality of water.
Sustainable replacement of EDTA–Biojarosite for commercial iron in the Fenton's and UV–Fenton's degradation of Rhowedamine B – a process optimization using Box–Behnken method
Authors: S Bhaskar , Rashmishree K. N. , Manu B. , Sreenivasa M. Y.
Published: October 2022

Biojarosite as a replacement for commercial iron catalyst in the oxidative degradation of the dye Rhodamine B was confirmed and established. Investigations on the oxidative degradation by Fenton's oxidation and UV–Fenton's oxidation with EDTA at neutral pH were conducted and degradation of target compound was evaluated. UV–Fenton's oxidation was shown to be efficient over Fenton's oxidation in the degradation of Rhodamine B with removal efficiency of 90.0%. Design of Experiments was performed with Box–Behnken design. Investigation was conducted for the predicted values separately for both Fenton's oxidation and UV–Fenton's oxidation and the Rhodamine B removal was taken as response. Variable parameters biojarosite, H2O2 dosage and EDTA were optimized in the range of 0.1–1 g/L, 2.94–29.4 mM and 10–100 mM, respectively. A quadratic regression model is fitted for both Fenton's and UV–Fenton's oxidation. Analysis of variance (ANOVA) is performed and model fit is discussed.
Therapeutic Potential of Genistein: Preclinical Studies, Clinical
Evidence, and Nanotechnology Application
Authors: Coutinho Ana J. , Pinheiro Marina , Neves Ana R. , Pinto Madalena M.M.
Published: October 2022

Genistein (4’,5,7-trihydroxyisoflavone) is a natural plant-derived phytoestrogen
that can be found, for example, in soybean seeds. Genistein is present mainly in the
human diet and is a common precursor in the antimicrobial phytoalexins biosynthesis
and phytoanticipins in vegetables. The interest in genistein has increased due to its pharmacological
effects, including anti-cancer activity, neuroprotective effects, cardiovascular
protection, anti-inflammatory effects, antioxidant activity, and prevention of obesity.
The most challenging issue for improving genistein is its low oral bioavailability, which
has led to many animal and human pharmacokinetic studies and numerous clinical trials.
Several drug delivery systems have been developed to protect and stabilize genistein to
overcome the challenge of low bioavailability. This work concerns a revision of the literature
reporting nano and microformulations for genistein encapsulation, including lipid
nanoparticles, liposomes, tocotrienol-rich nanoemulsions, polymeric nanoparticles, dextran
complexes, chitosan complexes, and Fe3O4 nanoparticles with carboxymethylated
chitosan. Regarding the enormous potential of genistein, several clinical trials and marketed
formulations can be found in the market.
Nanotechnology for Targeted Drug Delivery to Treat Osteoporosis
Authors: Nagpal Manju , Kaur Malkiet , Aggarwal Geeta
Published: October 2022

Bone diseases such as rheumatoid arthritis, Paget's disease, and osteoporosis cause mor-tality and mobility limits. Nanomedicine and nano delivery systems have been utilised to deliver ac-tive drug moiety to the precisely targeted site in a controlled manner, and it serves as a means of di-agnostic tools. The utilisation of nanomedicine is expanding vigorously for assured targeting and efficient drug delivery. Nanotechnology offers various advantages, such as site-specific targeting, precise drug release kinetics, and improved bone mineral density. Recent medications available for osteoporosis are not viable due to the adverse effects associated with them and low patient compli-ance. There is an urgent need to develop biocompatible and appropriate drug delivery nanocarriers such as nanoparticles, liposomes, hydrogels, dendrimers, micelles, mesoporous particles, etc. These carriers enhance drug delivery and therapeutic effectiveness in bone tissues. The use of nanotech-nology is also associated with toxicity. This article presents the review of various reports on nanocarrier systems and biologics for the treatment of osteoporosis. It aims to provide researchers with a clue for inventing a new drug delivery system with site-specific targeting for the treatment of osteoporosis.
Chemotherapeutic Effects of Boswellic Acid Against Human Glioblastoma
Multiform: A Comprehensive Review
Authors: Ebrahimpour-Koujan Soraiya , Khajebishak Yaser , Roudini Kamran , Baziar Nima , Shabani Samaneh , Payahoo Laleh
Published: October 2022

Background:

Glioblastoma multiform (GBM) is a malignant subgroup of gliomas. Due to
the natural resistance of GBM cells to radio-and chemotherapy usually, recurrence occurs 6-9 months
after diagnosis.

Objective:

This paper reviewed the beneficial effects of Boswellic acid (BA) in adjacent therapy for
GBM, based on its possible molecular mechanisms.

Methods:

In this review paper, all papers indexed in scientific databases, including PubMed, Scopus,
Embase, Google Scholar, and Elsevier were searched during 2000 - 2021 using apoptosis, Boswellic
acid, cancer, glioblastoma multiform, inflammation, oxidative stress as keywords.

Results:

The most important compounds of BAs are alpha-boswellic acid, beta- boswellic acid, acetylbeta-
boswellic acid, acetyl-alpha- boswellic acid, and 11-keto-beta- boswellic acid (KBA). Antiinflammation,
reduction of skin irritation, anti-tumor, anti-cancer, anxiolytic, and anti-phlogistic are
the main properties of BAs. Boswellic acid is recognized as a chemopreventive agent. Boswellic acid
exerts its effects mainly via various mechanisms such as induction of apoptosis and cytotoxic effects
on malignant cells, activation of caspases, up-regulation of genes expression with potential antiapoptotic
and pro-survival properties, inhibition the signaling and activity pathway of nuclear factorkappa
B (NF-κB) and enhancing poly (ADP)-ribose polymerase (PARP) cleavage. Boswellic acid
inhibits the signaling pathway of 5 and 12-lipoxygenase (5, 12 LOX), and cyclooxygenase-2 (COX-2),
which are considered triggers in the production of inflammatory cytokines such as tumor necrosis
factor (TNF-α), and interleukin-1β (IL-1β).

Conclusion:

Future clinical trials are needed to identify the interaction between Boswellic acid and the
severity of GBM and to define the safe dose and effective duration of supplementation.
Yoruba ontology: Perception of the physical body of the dead and its implications for cadaveric organ transplantation in south-west Nigeria. Yoruba death ontology: implications for organ transplantation
Authors: Awobusuyi Jacob Olugbenga
Published: October 2022

Introduction: The perception of death differs by region, culture, religion, and ethnic group in Nigeria. These differences can affect the consent rate for cadaveric transplantation. Understanding the Yoruba concept of death and approaching families for consent in a culturally sensitive manner may increase family consent to deceased donor organ harvesting. This literature review explores the Yoruba concept of death and organ transplantation.Methods: Three research questions were formulated and a search strategy was drafted by creating a SPIDER (Sample, Phenomenon of Interest, Design, Evaluation, and Research type) logic search grid. Relevant databases were then examined using the search terms, concepts and keywords so generated. The findings of publications retrieved on Yoruba beliefs regarding death were entered into a summary table based on the themes identified in them. These themes served as the basis for the interpretation synthesis.Results: Fifteen of the eighty-five studies identified initially were deemed contextually relevant to the researchquestions and used in the analysis. These sources revealed that death in the Yoruba belief system signifies the dematerialization of the soul and its transformation from earthly existence into a spiritual one. Consequently, the physical body of the deceased is perceived as becoming dust and of little relevance to the afterlife.Conclusion: In the Yoruba worldview, the state of the physical body after death has no relevance to afterlife and reincarnation. However, transplant teams must consider the circumstances of death when asking for consent. When death is viewed positively, success is more likely. Keywords: Yoruba, death, ontology, organ transplantation
First language use among second language teachers: Views vs practice
Authors: Romli Noor Hayati Binti , Abd Aziz Mohd Sallehhudin Bin , N.Krish Pramela Krish
Published: October 2022

Although the Grammar Translation Method (GTM) had been shunned in second language teaching, the stigma of using the first language (L1) in teaching the second language (L2) has been continuously debated by scholars and teachers. Commonly, L2 teachers support the monolingual approach as they are exposed to this approach in their teaching training courses. However, previous studies revealed that teachers’ stance towards L2 teachers is contrary to how they utilise L1 practice in the teaching process. This research study aims to explore the use of L1 (Bahasa Melayu) by L2 (English) teachers during the teaching process and to examine whether their beliefs matched their L1 practice. A total of eight English teachers from several schools in Pahang, Malaysia were interviewed and their lessons were recorded. The data from the interviews and lessons were thematically analysed using NVivo 12 software. The results demonstrated that the teachers had utilised Bahasa Melayu (BM) for certain functions and that their beliefs towards L1 actually corresponded to their language use in the L2 classrooms. This study suggests that it is imperative to look further into this matter and assist teachers in systematically using L1 in the L2 classrooms.
Web-based instruments for national competences of physical education teachers
Authors: Suroto Suroto , Prakoso Bayu Budi , Priambodo Anung , Khory Fifukha Dwi , Dinata Vega Candra
Published: October 2022

Several studies believe that the use of national standards as a benchmark for teacher quality can align education services to achieve national goals. In addition, the number of years of teaching experience can determine teacher productivity during the course of their profession. This article explores the results of developing a teacher competency measurement instrument based on the Indonesian national standards, and evaluating teacher competency based on gender, grade, and working period. A total of 277 Physical Education (PE) teachers participated in an online survey via the web http://risetpjokindonesia.com/ to measure teacher competency. The measurement results were analyzed using confirmatory factor analysis and Cronbach's alpha to test validity and reliability. T-test and one-way ANOVA were used to evaluate teacher competency based on gender, grade, and working period. The findings show that the measurements made are valid and reliable, so they can be used for similar measurements in the future. Gender, grade, and working period were found to affect teacher competency. The development of teacher competency based on working period provides input in the form of accuracy of the teacher professional development carried out and the limitation of the productive period of the teacher in carrying out his or her profession.
The teaching readiness of pre-service teachers from the economics and business education programs
Authors: Siswanto Siswanto , Muhson Ali , Wibawa Eka Ary
Published: October 2022

This study aims to examine the teaching readiness level of pre-service teachers from the Economics Education, Accounting Education, and Office Administration Education study programs and the discrepancy between them. Ex post facto research design was applied in this study with quantitative approach. Pre-service teachers from educational study programs in the Faculty of Economics Universitas Negeri Yogyakarta that have completed micro teaching and educational practice courses were involved as the population in the present study. A total of 262 pre-service teachers were selected as the samples using purposive random sampling method. A questionnaire was used to collect the data. The instrument validity was confirmed using exploratory factor analysis, while the reliability was estimated using Cronbach Alpha. The data were analyzed statistically using descriptive quantitative and Multivariate Analysis of Variance (MANOVA). The result showed that the teaching readiness of the pre-service teachers from the Economic Education, Accounting Education, and Office Administration Education study programs were in the “excellent” category, and no significant differences were found on their teaching readiness level. The results indicated that each study program showed a similar performance in providing the pre-service teachers with an appropriate level of teaching readiness. Grounded on the research results, it is suggested to maintain the schooling pattern for all educational study programs for an in-depth study in the future with different characteristics of each study program.
Critical Thinking Skills and Sustainability Conciousness of Students for The Implementation Education for Sustainable Development
Authors: Sobari E. F. D. , Hernani H. , Ramalis T. R.
Published: October 2022

The study aimed to describe the critical thinking skills and sustainability consciousness of students of one junior high school in Bandung using an E-module of environmental pollution containing education for sustainability development (ESD). The research used descriptive qualitative and quantitative methods. This study involved 32 participants using a research instrument in the form of critical thinking skills essay questions that contained sustainability consciousness (ESD) with a total of 12 questions. The study indicated that critical thinking skills reach the highest score on the indicator of building basic skills of 78.1% and the lowest score on the concluding indicator of 64.8%. The average score of students' critical thinking skills was 74.4%, which showed the level of students' critical thinking skills in the adequate category. Meanwhile, the sustainability consciousness components showed that the sustainable knowledge, sustainable attitude, and sustainable behavior were constructed with percentages of 82.1%; 79.5%; and 77.8% indicating that the average students’ sustainability consciousness was 79.8% in the good category
Fluid shear stress on the endothelium of the carotid artery wall and coronary artery calcinosis in patients with arterial hypertension
Authors: Lobanova N. Iu. , Chicherina E. N. , Malchikova S. V. , Maksimchuk-Kolobova N. S.
Published: October 2022

Objective: to study the interconditionality of changes in the fluid shear stress on the endothelium (FSE) of the common carotid artery (CCA) wall which is intact from atherosclerosis with the value of the Cardiac Calcium Score (CCS) among patients with e arterial hypertension (AH).

Materials and methods: the study included 99 patients with AH, 52 of them had atherosclerotic lesions of the brachiocephalic arteries (BCA). The ultrasound investigation of the carotid arteries with the determination of FSE in the intact area of the CCA, multispiral computed tomography of the coronary arteries with the determination of CCS were performed to all patients.

Results: the prevalence of BCA atherosclerotic lesion in the study was 53%. The mean value of FSE for patients with AH and BCA atherosclerosis (group 1) were 660.7 (185.6) c-1, for patients with AH without its (group 2) — 735.8 (149.8) c-1, p = 0.009. The parameters of the lipid spectrum in patients of both groups were comparable. Мedian value of CCS in patients with atherosclerotic lesions of the BCA were statistically significantly higher (15.00 (0.00; 178.00),) compared with patients of the group 2 (0.00 (0.00; 171.00), at p = 0.001. The chances of detecting coronary artery calcification among patients of group 1 are in 2 times higher (OR = 2.25, 95% CI: 1.58-8.33) than among patients of group 2. Low FSE values correlated with male gender (rs = 0.40 (95% CI: 0.22; 0.55) p <0.001) and increasing of CCS (rs = -0.23 (95% CI: -0.41; -0.04) p = 0.022).

Conclusions: the prevalence of atherosclerotic lesions of the BCA among patients with AH without a history of symptomatic diseases associated with atherosclerosis was 53%. In the group of patients with AH and atherosclerotic lesions of the BCA, median values of CCS were significantly higher, and coronary artery lesions were detected significantly more often (OR = 2.25, 95% CI: 1.58-8.33) than among patients with AH and intact BCA. The mean value of FSE for patients with AH and BCA atherosclerosis were statistically significantly lower than for patients with AH without it and amounted to 660.7 (185.6) c-1 and 735.8 (149.8) c-1, respectively, p = 0.009. Low FSE values correlated with male gender and increasing of CCS
Clinical and epidemiological features of multiple sclerosis in Republic of Ingushetia
Authors: Goncharova Z. A. , Uzhakhov R. M. , Megeryan V. A.
Published: October 2022

Objective: to study clinical and epidemiological features and risk factors in patients with multiple sclerosis (MS) living in Rostov region and Republic of Ingushetia (RI)

Materials and methods: we examined 87 patients with definite multiple sclerosis. We evaluated neurological deficiency and the specificity of MS course. We have also studied serum concentration of vitamin D3 metabolite — 25(ОН)D3 by ELISA method.

Results: the prevalence of NS in RI was 16,9 cases for 100 thousand of the population as of 1.01.2022. Risk fаctors of MS dеvеlopment were cоntаct with pеtrоl, оil prоducts аnd pаints аt аgу оvуr 15 yеаrs оld, cоntаct with аnimаls аt аgе bеfоrе 15 yеаrs оld, a surgicаl intеrvеntiоn, sеvеrе cаriеs аt аgе оvеr 15 yеаrs оld, heаd injury at аny аgе, tоnsillitis, meаslеs, rubеllа оccurrеd аt аgе bеfоrе 7 yеаrs оld аnd hеrpеtic infеctiоn аt аny аgе, thе diffеrеncеs wеrе stаtisticаlly signifiаant. In fеmаlе MS pаtiеnts wе оbsеrvеd highеr pаrаmеtеrs of rеlаpsе frеquеncy аnd MS prоgrеssiоn sрееd, the diffеrеnсеs wеrе stаtisticаlly significаnt. Ассоrding tо thе cоmpаrisоn оf sеrum vitаmin D cоncеntrаtion wе rеvеаlеd a stаtisticаlly rеliаblе dеcrеasе of sеrum vitamin D lеvеl in male MS patients living in RI compared to the control group.

Conclusions: the regions of Republic of Ingushetia belong to the areas with low and medium multiple sclerosis development risk. The external factors of MS development risk confirm the multifactor nature of the disease. The decrease of serum vitamin D concentration is one of the main modifiable MS risk factors.
Paradoxes in embolism: management of a young female patient with atrial septal defect after acute myocardial infarction
Authors: Chumachenko N. V. , Kijvatova N. V. , Kosmacheva H. D. , Pakholkov A. N. , Fedorchenko A. N.
Published: October 2022

The article is devoted to a clinical case of management of a young woman with an aneurysm and two atrial septal defects after the development of acute myocardial infarction. It conveys aspects of differential diagnosis and long-term management.
Peran Digital Humanities dalam Upaya Regenerasi Sumber Daya Manusia untuk Mewujudkan Pembangunan Pertanian Berkelanjutan
Authors: Hariadi Sunarru Samsi , Handayani Ari Widya , Dewi Fortuna Puri Eka
Published: October 2022

Digital humanities is a meeting point between the humanities and the technological sciences with the aim of studying the use of digital tools in aspects of the humanities and how the humanities affect technology. Regarding the development of digital humanities and sustainable agricultural problems, this research is focused on looking at the interest of young people working in agriculture.  The purpose of this study is to find out: how the role of digital media (digital humanities) affects the interest of youth working in agriculture so that it can be realized the regeneration of agricultural human resources, what factors affect the interest of youth to work in agriculture, predicting the younger generation who will work in agriculture as an effort to regenerate in agriculture. The study was conducted in Klaten and Temanggung districts with 106 small samples of youth taken at random. To predict the younger generation who will work in agriculture using qualitative and quantitative statistical path analysis. The results stated that youth's interest in working in agriculture is influenced by youth attitudes towards the agricultural sector, social media utilization, self-efficacy, and the role of parents. The use of social media affects the attitude of youth in agriculture and youth self-efficacy. Efforts that can be made to increase the interest of youth working in agriculture include strengthening self-efficacy and attitudes in agriculture by optimizing the role of parents and the use of social media to get information in agriculture.
Experimental Investigation of the Effect of Curvature Ratio on Heat Transfer in Double Pipe Helical Heat Exchanger
Authors: Hoshi Hisham Assi
Published: October 2022

Different parameters of double pipe helical coil were investigation experimentally. Four coils were used; three with a curvature ratio (0.037, 0.031, and 0.028) and 11mm diameter of the inner tube while the fourth with 0.033 curvature ratio and 13 mm diameter of the inner tube. The hot water flow in the inner tube whereas the cold water flows in the annulus. The inlet temperatures of hot and cold water are 50 0C and 18 0C respectively. The inner mass flow rate ranges from 0.0167 to 0.0583 kg/s. The results show the Nusselt number increase with increase curvature ratio. The Nusselt number of the coil with 0.037 curvature ratio increases by approximately 12.3 % as compare with 0.028 curvature ratio. The results also reveal that the Nusselt number of the coil with curvature ratio 0.033 increases by approximately 11.6 % as compare with 0.028 curvature ratio for 400 mm coil diameter.
A Review Paper on Predicting Different Types of Strokes
Authors: Heggade Amita Chaitra , Rafi Dr. Mohamed
Published: October 2022

Abstract: Now-a-days stroke is one of the most life threatening disease to all most all theage groups. It injures the brain similar to “heart attack” which injures the heart. Stroke is given the second leading cause of death in many of the developing countries. Every four minutes someone dies because of stroke, and itis said that up to 80% of strokes can be prevented if we identify them in early stages orpredict the occurrence of stroke in its early stage. The majority of research has focused onthe prediction of heart stroke, while just a few studies have looked at the likelihood of a brainstroke. Brain disorders can represent a tickingbomb under Europe’s economy due to their enormous societal costs, which are set to growwith the aging of the European population. Addressing these large costs for the societyrequires an intensified research and novel solutions. To face this societal emergency, we need to develop a strong network for both basicand clinical brain research.
Grower’s Guide: A Review for Sustainable Production of Okra (Abelmoschus Esculentus) in West Africa and Other Regions
Authors: Davis Thomas Wilbur
Published: October 2022

Abstract: This paper provides detailed information specifically the botany, history, and current statistical report on okra as well as how it is cultivated. Major biotic and abiotic stress factors impeding the production of okra and the sustainability aspect in the production of the crop are discussed. Many reasons for poor growth and development, low yield of okra as well as seed dormancy or okra plant death are mentioned. These include poor quality of seed and some biotic stresses particularly yellow vein mosaic virus (YVMV) and abiotic stresses such as salinity, drought, various water stresses and high moisture content. However, okra as a tropical and subtropical crop is drought-resistant, thus does well under drought conditions. Notwithstanding, high moisture content, salinity, and the yellow vein mosaic virus disease are the major factors affecting the crop. These conditions especially the yellow vein mosaic virus disease reduce okra yield to about 94% depending on the time of infestation after germination. To control the mosaic virus disease, very limited success has been achieved by chemical methods (including the application of neem oil, Acetamiprid, Imidacloprid and Trizophos), which also are not permanent since some resistant cultivar become susceptible with time. Therefore, advance breeding and development of host resistance to viruses and measures to combat salinity are the important strategies against these impeding conditions.
Rheology of Slurry: A Review
Authors: Mishra Sai Swapnesh , Parida Ashish Kumar , Das Anurag , Saha Shrutam , Kumar Tushar
Published: October 2022

Abstract: In this paper, the rheological parameters, characterisation, and the rheological behaviour of mineral ore slurry are reviewed and discussed in detail. Rheology is a study of flow phenomenon of matter, parameters like viscosity and the relationship between stress, strain, and time for the matter are helpful in defining rheology, these parameters have helped in classification of fluids into two broad categories - Newtonian and Non-Newtonian fluids. The rheological characteristics have a great impact in design and operation of the pipelines. This paper has a special emphasis on the iron ore slurry and its rheological behaviors which are highly affected by several physical and chemical properties (particle shape, particle size distribution, shear rate, pH value, solid concentration, viscosity, and slurry temperature) which also have been explained in particulars. The importance of rheology in slurry transportation makes it really important to define ways for controlling rheology that have proven to be helpful in stabilizing the slurry thus making the operation more efficient. Rheology is a major factor that affects the process of pipeline transportation of slurry which makes it such an important topic of study and research.
Role of Convolutional Neural Networks to Diagnosis Medical Images
Authors: Kaur Gurjeet , Singh Dr. Sukhwinder
Published: October 2022

Abstract: Numerous ailments are plaguing people today. These health issues cannot be ignored because they pose a threat to our lives. Additionally, the healthcare industry is totally unique compared to other area. Patients, regardless of cost, expect the greatest level of care and services in this high priority industry. Most often, medical professionals analyses the interpretations of medical data. Due to subjectivity and the complexity of the medical images, a medical expert's ability to interpret images is relatively limited. In addition, there are other problems with medical images, including low contrast, speckle noise, gaussian noise, and other artefacts. Therefore, it is imperative to have high image quality to extract relevant information from images for precise disease detection. Early detection and prevention are therefore needed to help people avoid these types of health issues. As a result of its success in other real-world applications, deep learning is viewed as offering innovative and precise solutions for medical imaging and is recognized as a significant technique for upcoming applications in the healthcare industry. The objective of this paper is discussing Convolutional neural networks (CNN), a deep learning algorithm. Additionally, CNN's goals and objectives are revealed in different medical terms especially in kidney stone problem diagnosis.
Challenges for sustainable urban transformation in São Paulo: visions, interests and demands under debate
Authors: Back Adalberto Gregório , Di Giulio Gabriela Marques , Malheiros Tadeu Fabrício
Published: October 2022

The objective of this article is to map the main actors that seek to exert influence in the regulatory arena of urban policy in São Paulo and to identify whether they converge or not with the principles of sustainable urban transformation, according to the precepts of a compact city, with low-carbon emissions, and which aims to reduce social inequalities and promote environmental qualification. Two attempts to change the zoning law, which ocurred in 2018 and 2019, have been chosen as the stage for analysis. Among the main actors and interests in dispute in this arena, the study has identified real estate developers (increased profit margin), neighborhood associations in the expanded central area of the city (protection of local characteristics) and social movements for housing (accessible decent housing). Within this context, the present article discusses the main pressures for changes in the socio-political pact defined by the 2014 São Paulo Master Plan.
Desafios para transformação urbana sustentável em São Paulo: visões, interesses e demandas em disputa
Authors: Back Adalberto Gregório , Di Giulio Gabriela Marques , Malheiros Tadeu Fabrício
Published: October 2022

O objetivo deste artigo é mapear os principais atores que buscam exercer influência na arena regulatória da política urbana paulistana e identificar suas convergências ou não com princípios de transformação urbana sustentável, conforme preceitos de uma cidade compacta, de baixa emissão de carbono, que visa a reduzir desigualdades socioterritoriais e promover qualificação ambiental. Elegeu-se como arena de análise duas tentativas de alteração extemporânea da lei de zoneamento, ocorridas em 2018 e 2019. Entre os principais atores e interesses em disputa nessa arena, identificaram-se incorporadoras imobiliárias (aumento da margem de lucro), associações de bairro presentes no centro expandido da cidade (proteção das características da localidade) e movimentos sociais por moradia (habitação digna acessível). Nesse contexto, o artigo discute as principais pressões para alterações do pacto sociopolítico definido pelo Plano Diretor de São Paulo de 2014.
Monitorando e avaliando políticas de esporte e lazer no Brasil: a experiência dos Programas Esporte e Lazer da Cidade (PELC) e Vida Saudável (VS)
Authors: Menegaldo Pedro Henrique Iglesiaz , Malagutti João Paulo Melleiro , Souza Juliano De , Starepravo Fernando Augusto
Published: October 2022

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Plano de expansão dos laboratórios de prótese dentária: pré-avaliação no estado da Bahia
Authors: Santos Lília Paula de Souza , Chaves Sônia Cristina Lima , Pinto Fernanda Mamede Oliveira , Lima Daniela Coelho de Souza
Published: October 2022

O Plano de Expansão dos Laboratórios de Prótese Dentária, na Bahia, foi instituído visando garantir o acesso à prótese dentária, à população em situação de extrema pobreza. Objetivando aferir a avaliabilidade desse plano, realizou-se a análise documental de publicações oficiais, entrevistas com informantes-chave e elaboração do modelo lógico preliminar da intervenção. O plano está implantado e proporcionou ampliação da oferta pública de prótese dentária. O tratamento dentário ocorrido durante o processo de preparação para o recebimento da prótese se revelou como meio de acesso e promoção à saúde bucal. Entretanto, há fragilidades no levantamento da necessidade de prótese dentária, articulação intersetorial, registro, avaliação e monitoramento das atividades.
Avaliação da aprendizagem na educação superior: cooperação e inovação
Authors: Santos Solidia Elizabeth , Fernandes de Oliveira Marcia Maria , Rodrigues Sonia Caranhato , Dahle de Almeida Siderly Do Carmo
Published: October 2022

O presente artigo teve como objetivo discutir sobre os modelos de avaliação de aprendizagem adotados pelos professores e seus impactos no aprendizado dos alunos. As reflexões foram extraídas de relatos dos alunos sobre a experiência vivida na disciplina de macroeconomia em uma Instituição de Ensino Superior – IES localizada em Curitiba, Paraná, no primeiro semestre de 2021, em um curso da área de Ciência Social aplicada. O modelo de avaliação adotado na disciplina foi a elaboração de um e-book, ancorado na perspectiva de Vygotsky (1987), que defende o princípio da interação e da cooperação na construção do aprendizado. Teve como alicerce a análise quantitativa de conteúdo de Bardin (2016). Os resultados chamaram atenção para a aprendizagem colaborativa, a construção do conhecimento de forma contínua, a utilização de metodologias ativas, a flexibilidade, dentre outros.
Competências necessárias aos avaliadores: uma síntese das principais listas presentes na literatura
Authors: Silva Castro Luis Carlos Da , Brazileiro Paixão Roberto
Published: October 2022

Dispor de uma lista de competências necessárias aos avaliadores possibilita a identificação de caminhos para o desenvolvimento profissional dos avaliadores. Este artigo tem o objetivo de analisar as principais listas de necessárias aos avaliadores e identificar semelhanças e diferenças entre elas. Pôde-se verificar que há uma grande diversificação das competências apresentadas nas diferentes listas, bem como uma elevada atenção com a dimensão Metodologia. As competências relacionadas diretamente à ética profissional, a aspectos de coleta, análise dos dados e relacionamento interpessoal, bem como à gestão de projeto são as que predominam nas listas elencadas. A maioria das competências listadas por King, Stevahn, Ghere e Minnema (2001) foram incluídas nas demais listas, o que sugere a importância deste estudo como ponto de partida para listas mais contextualizadas.
A study of the relationship between online movie reviews and the intention to watch the movie
Authors:   Department of Business Administration, College of Management, Shih Chien University, Taipei City, Taiwan, Shieh Hwai-Shuh , Lin Szu-Yu ,   Institute of Business and Management, College of Management, National Yang Ming Chiao Tung University, Taipei City, Taiwan
Published: October 2022

Aim/purpose – This study explores how the content feature and source of eWOM affect people’s intentions and further analyses the effectiveness of eWOM on people’s inten- tion to watch movies. Design/methodology/approach – The study considers two dimensions of movie reviews, including the source (anonymous or acquaintance) and the content feature (con- crete or abstract), adopts a 2x2 between-subject design, and then analyzes online ques- tionnaires (N = 313) via statistics analysis methods. Findings – The findings showed that if the source is from an acquaintance and the con- tent feature is concrete, then people will have the highest intention to watch the movie. In addition, the acting skills of the cast and the love of the movie genre also enhance the positive influence on the viewer’s experience. Research implications/limitations – The respondents were selected only in Taiwan so this paper do not explain any differences among different countries. For example, cultur- al differences exist between the West and the East in the content feature of eWOM. Originality/value/contribution – If a type of genre is greatly accepted by the audience and generates huge box-office revenue, then producers and movie companies might keep making movies in these kinds of genre to secure profits. Therefore, box-office movies will usually fall into these certain types of genres, and there will be an abundance of them released in the near future. Keywords: source of eWOM, content feature of eWOM, online movie review, between- -subject design. JEL Classification: C12, C90.
Study of Prescribing Pattern and Evaluation of the Efficacy of Monotherapy vs. Polytherapy Antihypertensive Drugs in Diabetes Patients
Authors: Aghili Mina , H.S. Shekar
Published: October 2022

The monitoring pattern of antihypertensive drugs and evaluation of the efficacy of prescribed pharmacological regimen can provide important vision into control of hypertension and prevention of related comorbidities. This study aimed to evaluate prescribing patterns and efficacy of prescribed monotherapy vs. polytherapy antihypertensive drugs in diabetes patients. A hospital-based prospective study was conducted in the medicine department of Kempegowda Institute of Medical Sciences Hospital and Research Center, Bangalore, India for a duration of 12 months. A total of 720 hypertensive patients with type 2 diabetes mellitus aged = 18 years were included in this study. Ninety patients (31%) were presented with chronic kidney disease, followed by ischemic heart disease (82, 28.3%), stroke (78, 26.9%), and heart failure (40, 13.8%). Monotherapy was prescribed more commonly than polytherapy (60.14% vs. 39.86%). The majority of patients were treated with Calcium channel blockers. In both therapeutic regimens, mono- and polytherapy, amlodipine was found to be the most prescribed drug. Comparison between results of antihypertensive monotherapy and polytherapy regimens (a combination of different classes of antihypertensive drugs) revealed that only prescription of polytherapy was associated with a statistically significant reduction in both systolic and diastolic blood pressure (mean (SD) of systolic blood pressure before polytherapy vs. after polytherapy; 166 (3.2) vs. 139 (1.4), < 0.0001. mean (SD) of diastolic blood pressure before polytherapy vs. after polytherapy; 103 (1.6) vs. 88 (0.5), < 0.0001). Systolic/diastolic blood pressure was not controlled and maintained within a therapeutic goal among patients who received single antihypertensive medication (monotherapy). Therefore, a combination of antihypertensive medications needs to be considered to achieve controlled blood pressure and avoid clinical inertia among hypertensive patients with diabetes.Â
The Determination of Trophic Level of Küçükçekmece Lagoon Lake (İstanbul, Türkiye) by Using Some Environmental Variables with Indicator Benthic Macroinvertebrates Findings
Authors: Aydın Gazel Burcu , Gürevin Cenk , Öterler Burak
Published: October 2022

In this study, to determine the trophic level of Küçükçekmece Lagoon Lake, water and sediment samplings were performed at five selected stations seasonally during a year between 2014-2015. The water samples were analyzed to determine some environmental variables (water temperature, pH, conductivity, DO (dissolved oxygen), TDS (total dissolved solids), and salinity. NO3-N, NO2-N, SO4-2, PO4-3, SiO2, chlorophyll-a, TP (total phosphorus), and Secchi disc light permeability) and benthic macroinvertebrates were examined to determine indicator organisms in the sampled sediment material. Bray-Curtis Similarity Index was used to the observed environmental results to determine the similarities of the sampling stations. According to this, station 1 (St. 1) located in the center of the lake, and St. 5 located near the sea were found to be different from other sampling stations while the stations located near the creeks were found to have much more similar to each other. In addition, to determine the trophy level of the lake, Carlson Trophic State Index (CTSI) was used to the obtained some physicochemical results (Secchi disc permeability, total phosphorus, chlorophyll-a) and it was found that the lake showed a eutrophic character during all seasons. According to the result of sediment sampling, an average of 350 individuals per m2 (44.3 % belonging Polychaeta group; 29.5 % belonging Chironomidae group; 19.7 % belonging Oligochaeta group; 6.5 % belonging Bivalvia group) in a total of 6 benthic macroinvertebrate taxa (Bivalvia, Polychaeta, Tubificoides benedii (Oligochaeta), Tubificoides sp. (immature Oligochaeta), Limnodrilus hoffmeisteri (Oligochaeta), and Chironomus salinarius (Chironomidae) were determined. Thus, it is observed that the presence of some indicator species supported eutrophic conditions qualitatively. As a result of this study, it was determined that Küçükçekmece Lagoon lake going on to expose the increasing pollution load.
Voces femeninas: Manifestaciones de violencia de género hacia las mujeres en el cuerpo policial de la Fuerza Pública en la Dirección Regional de San José durante el 2019
Authors: Castrillo-Castrillo Sarah
Published: October 2022

Este artículo presenta las vivencias relacionadas con la violencia de género en el ámbito laboral de las mujeres policías de la Dirección Regional de San José en el 2019. Para cumplir con sus objetivos, se aplicó una metodología mixta en la que se implementó una encuesta, dos grupos focales y entrevistas en profundidad. El propósito fundamental fue identificar las manifestaciones relacionadas con comportamientos machistas y de acoso por parte de hombres policías hacia sus compañeras. El análisis se realiza a partir de la comprensión de las estructuras patriarcales legitimadas institucionalmente que propician posiciones de poder ejercidas desde el machismo, lo cual afecta negativamente la vida y labor de las mujeres policías. Se finaliza con una reflexión de los resultados, teniendo en cuenta la relevancia de aplicar acciones que intervengan en esta problemática.
Inteligencias múltiples en la educación del siglo XXI
Authors: Orozco Giraldo Consuelo
Published: October 2022

En un mundo contingente y paradójico como el nuestro, el mismo que cambia a la velocidad del vértigo, insistir en una sola inteligencia con características meramente racionales y mesurable a través de test psicométricos no solo está en entredicho sino que, además, resulta un pecado capital contra la calidad educativa en general y los estudiantes, en particular. La inteligencia como concepto ha sido un tema inacabable hasta nuestros días en especial en el campo de la psicología y parece haberse instalado en la práctica educativa. Esos esfuerzos por conceptualizarla han servido en diferentes momentos de la historia de la educación tanto de motivo como de excusa para calificar, categorizar, diagnosticar, encasillar al estudiante; como también para diseñar apuestas curriculares, planes de curso y estrategias didácticas que a manera de fórmula mágica aplique para todos al margen del contexto, no es otro el escenario al que están siendo sometidos los estudiantes. Este libro da cuenta de la innegable presencia de las inteligencias múltiples en un grupo de estudiantes tanto dentro como fuera del aula y proporciona a manera de ejemplo, algunas estrategias que podrían ser adoptadas y adaptadas por el profesor de acuerdo a las necesidades del estudiante y del grupo.