bluuebunny/crossref_metadata_2025 huggingface dataset:
Zinc‐Binding Protein
Znu
A
Authors: Smith Thomas J , Pakrasi Himadri B
Published: December 2011

ZnuA is a high‐affinity, periplasmic zinc (Zn
2+
)‐binding protein that is a component of a three‐protein ABC transport system. The overall structure of ZnuA is very similar to the previously determined structures of the periplasmic domains of the ABC metal transporters PsaA and TroA. ZnuA has a ‘C clamp’ shape, which is composed of two (β/α)
4
domains related by pseudo twofold symmetry. Also like the other metal transporters, the two domains are linked by a 33‐residue α‐helix. This likely keeps the two domains in a relatively fixed position as made evident by the lack of large domain movement upon binding and release of metal. Unlike PsaA and TroA, however, there is an extended loop near the metal‐binding cleft, which is rich in histidines and acidic residues. Structural studies demonstrate that the removal of this loop does not affect the structure of ZnuA, and isothermal titration calorimetry (ITC) studies show that this loop contains low‐affinity zinc‐binding sites but does not directly affect the binding of zinc to the high‐affinity site within the cleft. Together, these results suggest that this unusual loop region may play a role in the regulation of zinc uptake when the periplasmic concentration of zinc is high.
Siderophore‐Binding Periplasmatic ProteinFhuDand Related Periplasmic Binding Proteins Involved in Bacterial Iron Uptake
Authors: Krewulak Karla D. , Köster Wolfgang , Vogel Hans J.
Published: December 2011

To fulfill their nutritional requirement for iron, many microorganisms synthesize low‐molecular‐weight iron‐chelating compounds calledsiderophores. These iron sources are transported into the gram‐negative bacterial cellviaspecific uptake pathways that include an outer membrane receptor, a periplasmic binding protein (PBP), and an inner membrane ATP‐binding cassette (ABC) transporter. Gram‐positive bacteria lack an outer membrane, and thus the uptake of the ferric siderophore involves a membrane‐anchored PBP and an ABC transporter. Siderophores are classified as hydroxamate, catecholate, or hydroxycarboxylate type siderophores. This review details what is currently known about the PBP, FhuD (Fhu — ferric hydroxamate uptake), involved in the uptake of hydroxamate‐type siderophores. In addition, several structurally related periplasmic binding proteins that mediate bacterial metal ion transport are also discussed.
Human FactorVIII
Authors: Ki Ngo Jacky Chi , Huang Mingdong , Roth David A. , Furie Barbara C. , Furie Bruce
Published: December 2011

Factor VIII is a critical blood clotting factor, which forms a complex with the serine protease factor IXa upon activation to convert factor X to factor Xa, which in turn activates thrombin. Deficiency or dysfunction of the protein leads to hemophilia A, a common X‐linked disorder. Structures of two different constructs of factor VIII have been determined by X‐ray crystallography at intermediate resolutions. Both structures show that the protein is composed of five globular domains and contains binding sites for calcium and copper ions, which are important in the regulation of factor VIII structure and activity. The three A domains, each consists of two β‐barrel structures that resemble the cupredoxin fold, are structurally homologous with one other. The two homologous C domains are defined by a distorted β‐barrel and reveal membrane‐binding features. Comparison of the two crystal structures has revealed structural differences between the two constructs and provides new perspectives for understanding the activation of factor VIII and the role of metal ions in the regulation of factor VIII activity.
Dissimilatory Adenosine‐5′‐Phosphosulfate Reductase
Authors: Schiffer Alexander , Fritz Günter , Büchert Thomas , Herrmanns Karolin , Steuber Julia , Ermler Ulrich , Kroneck Peter MH
Published: December 2011

The iron‐sulfur flavoenzyme adenosine‐5′‐phosphosulfate reductase (APSR) catalyzes the reductive cleavage of APS (adenosine‐5′‐phosphosulfate) to sulfite plus AMP and the reverse reaction, both important reactions within the biogeochemical sulfur cycle. The structure of the dissimilatory enzyme from the hyperthermophilic sulfate reducerArchaeoglobus fulgidusat 1.6 Å resolution reveals APSR as heterotetrameric α2ß2complex; however, the αß heterodimer is the functionally active unit. The FAD(flavin adenine dinucleotide) binding α‐subunit of APSR is structurally similar to the corresponding subunit of fumarate reductases, suggesting a common ancestor that resembles archaeal APSR. A clear separation is observed between the electron transfer process that extends over 25 Å from the protein surface via two [4Fe‐4S] clusters to thesi‐side of FAD and the chemical process of APS reduction at there‐side of FAD. The structures of APSR complex with the substrates APS, sulfite, and AMP trapped the enzyme in four different states and allowed, together with information from spectroscopic studies, to develop a detailed picture of the catalytic cycle. The nucleophilic attack of the N5 atom of FADH−onto the sulfur of APS, both negatively charged, proceeds in a compressed enzyme‐substrate complex relaxed in the formed FAD‐APS and FAD‐sulfite adducts.
Dissimilatory Sulfite Reductase
Authors: Parey Kristian , Schiffer Alexander , Steuber Julia , Fritz Günter , Ermler Ulrich , Kroneck Peter MH
Published: December 2011

Dissimilatory sulfite reductase (dSiR) belongs to the group of oxidoreductases and is a key enzyme of the biogeochemical sulfur cycle. The enzyme is organized as a heterotetrameric α2β2, or a heterohexameric α2β2γ2complex, and catalyzes the reduction of sulfite (SO32−) to hydrogen sulfide (H2S) in a six‐electron transfer process as the final step of dissimilatory sulfate reduction. Thiosulfate (S2O32−) and trithionate (S3O62−) have been postulated as potential intermediates in this energy conserving process, which evolved in an early stage of prokaryotic life in an anoxic environment. Like assimilatory sulfite reductase (aSiR), dSiR also reduces nitrite to ammonia. Sulfite reductases and related nitrite reductases are the only known class of enzymes that couple a siroheme (an iron‐tetrahydroporphyrin of the isobacteriochlorin class) to an iron–sulfur cluster to construct a catalytically active redox center.
Arsenite Oxidase
Authors: Hille Russ
Published: December 2011

The crystal structure of arsenite oxidase has been determined, and the enzyme found to represent a new subclass of the dimethyl sulfoxide (DMSO) reductase family of molybdenum‐containing enzymes. The enzyme also possesses a [3Fe–4S] iron–sulfur center in the same subunit as the molybdenum center, as well as a Rieske‐like [2Fe–2S] center in a separate, smaller, subunit. In addition to a detailed consideration of the enzyme's structure, its electrochemical and catalytic properties are discussed. Phylogenetic evidence is also discussed, suggesting that arsenite oxidase is an ancient enzyme arising before the diversification of the archaeal and eubacterial domains of life.
Manganese Catalase
Authors: Barynin Vladimir V , Whittaker James W
Published: December 2011

Manganese catalase (a.k.a. pseudocatalase, nonheme catalase) is an antioxidant defense metalloenzyme that is broadly distributed over prokaryotic life. While functionally related to heme catalases, manganese catalases have a distinct protein structure based on a four‐helix bundle architecture that is more closely related to the oxygen‐activating iron metalloproteins ferritin and ribonucleotide reductase. Manganese catalase contains a pair of manganese ions bound in the core of the four‐helix bundle in a solvent‐bridged binuclear cluster that serves as the catalytic active site for hydrogen peroxide disproportionation. Both metal ions are redoxactive, cycling between divalent and trivalent oxidation states during catalytic turnover.
The Nucleobase‐Cation‐Symport‐1 Family of Membrane Transport Proteins
Authors: Weyand Simone , Ma Pikyee , Saidijam Massoud , Baldwin Jocelyn , Beckstein Oliver , Jackson Scott , Suzuki Shun'ichi , Patching Simon G , Shimamura Tatsuro , Sansom Mark SP , Iwata So , Cameron Alexander D , Baldwin Stephen A , Henderson Peter JF
Published: December 2011

The evolutionary relationships of membrane transport proteins of the nucleobase‐cation‐symport (NCS‐1) family from bacteria, fungi, and plants are described. The reported substrates of the NCS‐1 family include nucleobases, hydantoins, and vitamins. Secondary active transport of substrate accompanied by a sodium ion, or possibly a proton, is the usual mechanism of energization. A strategy for the amplified expression, purification, and activity assays of bacterial members of the NCS‐1 family is described. Conditions are given for the production of diffracting crystals of one member, the Na+‐coupled transporter for aromatic hydantoins, ‘Mhp1’, fromMicrobacterium liquefaciens. The 3D structures of three forms of the Mhp1 protein are discussed in terms of one open‐outward, one substrate‐occluded, and one open‐inward conformation contributing to a molecular dynamics simulation of the alternating‐access model of membrane transport. The unexpected similarity of the protein fold of Mhp1 to those of transport proteins, hitherto thought to be from different evolutionary families, is discussed.
Phosphotriesterase
Authors: Bigley Andrew N , Raushel Frank M
Published: December 2011

Phosphotriesterase (PTE) is a member of the amidohydrolase superfamily with the ability to hydrolyze numerous organophosphate substrates including many insecticides and nerve agents. The native active site metal is zinc, but the enzyme is fully active with a variety of metals. The overall fold of PTE is a (β/α)8TIM‐barrel with the active site located at the C‐terminal end of the barrel. The active site contains the binuclear metal center with the metal ligands being four histidines, an aspartate, and a carboxylated lysine from the C‐terminal ends of the β‐strands. In addition, the metal center contains a bridging hydroxyl that serves as the nucleophile in the SN2‐like reaction. The substrate‐binding site is external to the metal center and is made of residues from the loops connecting the C‐terminal end of each β‐strand to the subsequent α‐helix. The best known substrate for PTE is the insecticide paraoxon, which has a kinetic efficiency that approaches the limits of diffusion. PTE has significant potential as an enzyme tool for the detection and decontamination of pesticides and nerve agents. Numerous variants of PTE have been developed by directed evolution with improved kinetic efficiency toward various organophosphates.
Cadmium‐Carbonic Anhydrase
Authors: Xu Yan , Supuran Claudiu T , Morel François M M
Published: December 2011

Cadmium‐carbonic anhydrase (CDCA1) is a ζ‐carbonic anhydrase (CA) isolated from the marine diatom
Thalassiosira weissflogii
, which naturally uses Cd as its metal cofactor. Its homolog gene has been found in a number of diatom species as well as natural assemblages. The expression of
cdca1
gene at both transcript and protein levels is regulated by pH/
p
CO
2
and Cd and Zn availabilities in seawater. The amino acid sequence contains a triple repeat with high identity among repeats, and each single repeat is a functional CA and a structural mimic of a functional β‐CA dimer. CDCA1 incorporates either Zn or Cd at its active site and readily exchanges one with the other. The metal cofactor is tetrahedrally coordinated by two Cys, a His, and a water molecule and an open conformation is adapted at the active site when the metal is absent. The catalytic efficiencies of both the Cd‐ and Zn‐bound CDCA1 are pH dependent and the Zn‐bound CDCA1 is more active than the Cd‐bound CDCA1.
Octaheme CytochromecNitrite Reductase
Authors: Tikhonova Tamara V , Polyakov Konstantin M , Boyko Konstantin M , Safonova Tatiana N , Popov Vladimir O
Published: December 2011

Octaheme cytochromecnitrite reductase (TvNiR) from bacteriumThioalkalivibrio nitratireducenscatalyzes the six‐electron reduction of nitrite and two‐electron reduction of hydroxylamine to ammonium without release of any intermediates. TvNiR also catalyzes the six‐electron reduction of sulfite to sulfide. High‐resolution structures of the TvNiR apo‐form and its complexes with the substrates (nitrite and sulfite) and inhibitors (azide and phosphate) were obtained. The subunit of TvNiR consists of two domains. The N‐terminal domain has a unique fold and contains three hemes. The remaining five hemes are located in the catalytic C‐terminal domain, with the heme arrangement, including the catalytic heme, being identical to that found in pentaheme cytochromecnitrite reductases (ccNiRs). The catalytic machinery of TvNiR resembles that of ccNiRs. It comprises the lysine residue in the proximal position of the catalytic heme, the catalytic triad of tyrosine, histidine, and arginine on the distal side, channels for the substrate and product transport, and two conserved Ca2+‐binding sites. The complete set of eight hemes forms a spatial pattern characteristic of other structurally characterized octaheme cytochromes. In the crystalline state and in solution, TvNiR exists as a stable hexamer containing 48 hemes, which are clustered into three isolated groups, each group comprising 16 interacting hemes.
Human Cytosolic
X
‐Prolyl Aminopeptidase
Authors: Li Xin , Bartlam Mark , Rao Zihe
Published: December 2011

X‐prolyl aminopeptidases catalyze the removal of a penultimate prolyl residue from the N‐termini of peptides. Mammalian X‐prolyl aminopeptidases are responsible for the degradation of bradykinin, a blood pressure regulator peptide, and have been linked to myocardial infarction. The X‐ray crystal structure of human cytosolic X‐prolyl aminopeptidase (XPNPEP1) reveals a dimer with a unique three‐domain organization in each subunit, rather than the two domains common to all other known structures of X‐prolyl aminopeptidases and prolidases. The C‐terminal catalytic domain of XPNPEP1 coordinates two metal ions and shares a similar fold with other prolyl aminopeptidases. Metal content analysis and activity assays confirm that the enzyme is double Mn(II) dependent for its activity, which contrasts with the previous notion that each XPNPEP1 subunit contains only one Mn(II) ion.
Peptidyl‐α‐Hydroxyglycine α‐Amidating Lyase (PAL)
Authors: Chufán Eduardo E , Eipper Betty , Mains Richard , Amzel Mario L
Published: December 2011

Many peptide hormones and neuropeptides require an amidated carboxy terminal for full biological activity. This reaction is carried out in two steps: hydroxylation of a C‐terminal glycine and cleavage of the C N bond with the release of glyoxylate. The enzyme peptidyl‐α‐hydroxyglycine α‐amidating lyase (PAL; EC 4.3.2.5) catalyzes the second step of this reaction,N‐dealkylation of the peptidyl‐α‐hydroxyglycine to generate the α‐amidated peptide and glyoxylate. The X‐ray crystal structure of the PAL catalytic core (PALcc), alone and in complex with the nonpeptidic substrate α‐hydroxyhippuric acid, shows that PAL folds as a six‐bladed β‐propeller. The active site is formed by a Zn2+ion coordinated by three histidine residues; the substrate binds to this site with its α‐hydroxyl group coordinated to the Zn2+ion. A tyrosine residue (Tyr654) at the active site acts as the catalytic base for hydroxyl deprotonation, an unusual role for tyrosine residue. In the reaction mechanism, proposed on the basis of the structure and validated by biochemical analysis of site‐directed PALcc mutants, the substrate α‐hydroxyl that coordinates the catalytic Zn2+directly is deprotonated by Tyr654. The generation of the required tyrosinate is aided by an arginine residue that, together with the Zn2+, lowers the pKaof the catalytic tyrosine.
Etherification of Functionalized Phenols with Chloroheteroarenes at Low Palladium Loading: Theoretical Assessment of the Role of Triphosphane Ligands in CO Reductive Elimination
Authors: Platon Mélanie , Cui Luchao , Mom Sophal , Richard Philippe , Saeys Mark , Hierso Jean‐Cyrille
Published: December 2011

The present study highlights the potential of robust tridentate ferrocenylphosphanes with controlled conformation as catalytic auxiliaries in CO bond formation reactions. Air‐stable palladium triphosphane systems are efficient for selective heteroaryl ether synthesis by using as little as 0.2 mol% of catalyst. These findings represent an economically attractive and clean etherification of functionalized phenols, electron‐rich, electron‐poor and para‐, meta‐ or ortho‐substituted substrates, with heteroaryl chlorides, including pyridines, hydroxylated pyridine, pyrimidines and thiazole. The etherification tolerates very important functions in various positions, such as cyano, methoxy, amino, and fluoro groups, which is useful to synthesize bioactive molecules. DFT studies furthermore demonstrate that triphosphane ligands open up various new pathways for the CO reductive elimination involving the third phosphane group. In particular, the rate for one of these new pathways is calculated to be about 1000 times faster than for reductive elimination from a complex with a similar ferrocenyl ligand, but without a phosphane group on the bottom Cp‐ring. Coordination of the third phosphane group to the palladium(II) center is calculated to stabilize the transition state in this new pathway, thereby enhancing the reductive elimination rate.
Semi‐parametric area under the curve regression method for diagnostic studies with ordinal data
Authors: Rajan Kumar B. , Zhou Xiao‐Hua
Published: December 2011

The classification accuracy of new diagnostic tests is based on receiver operating characteristic (ROC) curves. The area under the ROC curve (AUC) is one of the well‐accepted summary measures for describing the accuracy of diagnostic tests. The AUC summary measure can vary by patient and testing characteristics. Thus, the performance of the test may be different in certain subpopulation of patients and readers. For this purpose, we propose a direct semi‐parametric regression model for the non‐parametric AUC measure for ordinal data while accounting for discrete and continuous covariates. The proposed method can be used to estimate the AUC value under degenerate data where certain rating categories are not observed. We will discuss the non‐standard asymptotic theory, since the estimating functions were based on cross‐correlated random variables. Simulation studies based on different classification models showed that the proposed model worked reasonably well with small percent bias and percent mean‐squared error. The proposed method was applied to the prostate cancer study to estimate the AUC for four readers, and the carotid vessel study with age, gender, history of previous stroke, and total number of risk factors as covariates, to estimate the accuracy of the diagnostic test in the presence of subject‐level covariates.
Targeting Zinc Finger Domains with Small Molecules: Solution Structure and Binding Studies of the RanBP2‐Type Zinc Finger of RBM5
Authors: Farina Biancamaria , Fattorusso Roberto , Pellecchia Maurizio
Published: December 2011

The RNA binding motif protein 5 (RBM5), also known as Luca15 or H37, is a component of prespliceosomal complexes that regulates the alternative splicing of several mRNAs, such as Fas and caspase‐2. The RBM5 gene is located at the 2p21.3 chromosomal region, which is strongly associated with lung cancer and many other cancers. Both increased and decreased levels of RBM5 can play a role in tumor progression. In particular, downregulation of rbm5 is involved in lung cancer and other cancers upon Ras activation, and, also, represents a molecular signature associated with metastasis in various solid tumors. On the other hand, upregulation of RBM5 occurs in breast and ovarian cancer. Moreover, RBM5 was also found to be involved in the early stage of the HIV‐1 viral cycle, representing a potential target for the treatment of the HIV‐1 infection. While the molecular basis for RNA recognition and ubiquitin interaction has been structurally characterized, small molecules binding this zinc finger (ZF) domain that might contribute to characterizing their activity and to the development of potential therapeutic agents have not yet been reported. Using an NMR screening of a fragment library we identified several binders and the complex of the most promising one, compound 1, with the RBM5 ZF1 was structurally characterized in solution. Interestingly, the binding mechanism reveals that 1 occupies the RNA binding pocket and is therefore able to compete with the RNA to bind RBM5 RanBP2‐type ZF domain, as indicated by NMR studies.
Gold Nanoparticles Incarcerated in Nanoporous Syndiotactic Polystyrene Matrices as New and Efficient Catalysts for Alcohol Oxidations
Authors: Buonerba Antonio , Cuomo Cinzia , Ortega Sánchez Sheila , Canton Patrizia , Grassi Alfonso
Published: December 2011

The controlled synthesis of gold nanoparticles (AuNPs), incarcerated in a semicrystalline nanoporous polymer matrix that consisted of a syndiotactic polystyrene‐co‐cis‐1,4‐polybutadiene multi‐block copolymer is described. This catalyst was successfully tested in the oxidation of primary and secondary alcohols, in which we used dioxygen as the oxidant under mild conditions. Accordingly, (±)‐1‐phenylethanol was oxidised to acetophenone in high yields (96 %) in 1 h, at 35 °C, whereas benzyl alcohol was quantitatively oxidised to benzaldehyde with a selectivity of 96 % in 6 h. The specific rate constants calculated from the corresponding kinetic plots were among the highest found for polymer‐incarcerated AuNPs. Similar values in terms of reactivity and selectivity were found in the oxidation of primary alcohols, such as cinnamyl alcohol and 2‐thiophenemethanol, and secondary alcohols, such as indanol and α‐tetralol. The remarkable catalytic properties of this system were attributed to the formation, under these reaction conditions, of the nanoporous ε crystalline form of syndiotactic polystyrene, which ensures facile and selective accessibility for the substrates to the gold catalyst incarcerated in the polymer matrix. Moreover, the polymeric crystalline domains produced reversible physical cross‐links that resulted in reduced gold leaching and also allowed the recovery and reuse of the catalyst. A comparison of catalytic performance between AuNPs and annealed AuNPs suggested that multiple twinned defective nanoparticles of about 9 nm in diameter constituted the active catalyst in these oxidation reactions.
Molecular Recognition at the Active Site of Factor Xa: Cation–π Interactions, Stacking on Planar Peptide Surfaces, and Replacement of Structural Water
Authors: Salonen Laura M. , Holland Mareike C. , Kaib Philip S. J. , Haap Wolfgang , Benz Jörg , Mary Jean‐Luc , Kuster Olivier , Schweizer W. Bernd , Banner David W. , Diederich François
Published: December 2011

Factor Xa, a serine protease from the blood coagulation cascade, is an ideal enzyme for molecular recognition studies, as its active site is highly shape‐persistent and features distinct, concave sub‐pockets. We developed a family of non‐peptidic, small‐molecule inhibitors with a central tricyclic core orienting a neutral heterocyclic substituent into the S1 pocket and a quaternary ammonium ion into the aromatic box in the S4 pocket. The substituents were systematically varied to investigate cation–π interactions in the S4 pocket, optimal heterocyclic stacking on the flat peptide walls lining the S1 pocket, and potential water replacements in both the S1 and the S4 pockets. Structure–activity relationships were established to reveal and quantify contributions to the binding free enthalpy, resulting from single‐atom replacements or positional changes in the ligands. A series of high‐affinity ligands with inhibitory constants down to Ki=2 nM were obtained and their proposed binding geometries confirmed by X‐ray co‐crystal structures of protein–ligand complexes.
ChemInform Abstract: Pressure‐Induced Formation of Molecular B2X4(μ‐X)2 (X: Cl, Br, I) Species.
Authors: Patchkovskii Serguei , Klug Dennis D. , Yao Yansun
Published: December 2011

Gas‐phase formation and decomposition of the boron(III) halides of title is explored by CCSD(T) and MP2 ab initio calculations.
ChemInform Abstract: MIIGe(PO4)2 (M: Ca, Sr, Ba): Crystal Structure, Phase Transitions and Thermal Expansion.
Authors: Popa Karin , Wallez Gilles , Bregiroux Damien , Loiseau Pascal
Published: December 2011

The title compounds are prepared by solid state reaction of stoichiometric amounts of MCO3 (M: Ca, Sr, Ba), GeO2, and NH4H2PO4 (1000—1150 °C, 18—100 h).
ChemInform Abstract: Synthesis, Structure, and Thermally Stable Luminescence of Eu2+‐Doped Ba2Ln(BO3)2Cl (Ln: Y, Gd and Lu) Host Compounds.
Authors: Xia Zhiguo , Wang Xiaoming , Wang Yingxia , Liao Libing , Jing Xiping
Published: December 2011

Powders of Ba2Ln(BO3)2Cl:0.03Eu2+ (Ln: Y, La—Nd, Sm—Lu) are prepared by solid state reaction of BaCO3, Ln2O3 (except for CeO2 and Tb4O7), H3BO3, BaCl2, and Eu2O3 (CO atmosphere,1000 °C, 3 h).
ChemInform Abstract: Site‐Preferential Design of Itinerant Ferromagnetic Borides: Experimental and Theoretical Investigation of MRh6B3 (M: Fe, Co).
Authors: Misse Patrick R. N. , Gillessen Michael , Fokwa Boniface P. T.
Published: December 2011

Polycrystalline samples of the title compounds and single crystals of CoRh6B3 are prepared by arc‐melting of the elements.
ChemInform Abstract: Two New Cluster Ions, Ga[GaH3]5‐4 with a Neopentane Structure in Rb8Ga5H15 and [GaH2]n‐n with a Polyethylene Structure in Rbn(GaH2)n, Represent a New Class of Compounds with Direct Ga—Ga Bonds Mimicking Common Hydrocarbons.
Authors: Fahlquist Henrik , Noreus Dag , Callear Samantha , David William I. F. , Hauback Bjoern C.
Published: December 2011

The title compounds are prepared from mixtures of Ga and Rb under 5 MPa H2 at 573 K and characterized by powder XRD and neutron powder diffraction.
ChemInform Abstract: Antiferromagnetic Ground State of Quantum Spins in the Synthetic Imanite, Ca3Ti2Si3O12: The Lost Child of the Garnet Family.
Authors: Valldor Martin , Urthe Andre , Rueckamp Reinhard
Published: December 2011

Large single crystals of the title compound are grown from mixtures of CaSiO3, Ti2O3, and Ti by the floating zone technique.
ChemInform Abstract: Two Open‐Framework Germanates with Nickel Complexes Incorporated into the Framework.
Authors: Huang Shiliang , Christensen Kirsten , Peskov Maxim V. , Yang Sihai , Li Kuo , Zou Xiaodong , Sun Junliang
Published: December 2011

The crystal structures of (III) and (IV) are determined by single crystal XRD.
ChemInform Abstract: [Pd3Sn8Bi6]4‐: A 14‐Vertex Sn/Bi Cluster Embedding a Pd3 Triangle.
Authors: Lips Felicitas , Clerac Rodolphe , Dehnen Stefanie
Published: December 2011

Black rhombus‐like crystals of [K([2.2.2]crypt)]4 [Pd3Sn8Bi6]·0.6en are synthesized from a mixture of [K([2.2.2]crypt)]2[Sn2Bi2]·en dissolved in en and Pd(dppe)2 (dppe: bis[1,2‐bis(diphenylphosphino)ethane]) suspended in toluene (3 h, 15% yield).
ChemInform Abstract: Readily Accessible Chiral Diene Ligands for Rh‐Catalyzed Enantioselective Conjugate Additions of Boronic Acids.
Authors: Trost Barry M. , Burns Aaron C. , Tautz Thomas
Published: December 2011

The chiral diene ligand is prepared from commercial materials in simply 2 steps remarkably compared to formerly described 6 or 7 steps.
ChemInform Abstract: In situ Generation and Intramolecular Schmidt Reaction of Keto Azides in a Microwave‐Assisted Flow Format.
Authors: Painter Thomas O. , Thornton Paul D. , Orestano Mario , Santini Conrad , Organ Michael G. , Aube Jeffrey
Published: December 2011

The scope and limitations of the title two‐step method are studied for cyclic and acyclic chloro‐ or bromoalkyl ketones.
ChemInform Abstract: Palladium‐Catalyzed Regioselective Aerobic Oxidative C—H/N—H Carbonylation of Heteroarenes under Base‐Free Conditions.
Authors: Zhang Hua , Liu Dong , Chen Caiyou , Liu Chao , Lei Aiwen
Published: December 2011

Using air as oxidant and a balloon pressure of CO, indoles, thiophenes and benzothiophenes are converted in the presence of different alcohols into carboxylic acid esters.
ChemInform Abstract: (Bromodimethyl)sulfonium Bromide Mediated Rapid and Facile Protection of Amines.
Authors: Shailaja M. , Manjula A. , Rao B. Vittal
Published: December 2011

Bromodimethylsulfonium bromide catalyzes both Cbz‐ and Boc‐protection of a wide variety of primary and secondary amines.
ChemInform Abstract: La/Ag Heterobimetallic Cooperative Catalysis: A Catalytic Asymmetric Conia‐Ene Reaction.
Authors: Matsuzawa Akinobu , Mashiko Tomoyuki , Kumagai Naoya , Shibasaki Masakatsu
Published: December 2011

A new catalyst system consisting of La(O‐iPr)3 and AgO‐Ac as hard and soft Lewis acids and an amide‐based ligand ((S)‐(I)) is used for the simultaneous activation of intramolecular 1,3‐dicarbonyl and alkyne moieties to afford enantioenriched cyclopentane derivatives.
ChemInform Abstract: Interception of a Rautenstrauch Intermediate by Alkynes for [5 + 2] Cycloaddition: Rhodium‐Catalyzed Cycloisomerization of 3‐Acyloxy‐4‐ene‐1,9‐diynes to Bicyclo[5.3.0]decatrienes.
Authors: Shu Xing‐zhong , Huang Suyu , Shu Dongxu , Guzei Ilia A. , Tang Weiping
Published: December 2011

The intramolecular [5 + 2] cycloaddition is accompanied by a 1,2‐acyloxy migration to produce various ring systems annellated with a cycloheptatriene moiety.
ChemInform Abstract: Hydrogenation of Azides over Copper Nanoparticle Surface Using Ammonium Formate in Water.
Authors: Ahammed Sabir , Saha Amit , Ranu Brindaban C.
Published: December 2011

The procedure provides a new, simple, efficient, and chemoselective access to amines and sulfonamides.
ChemInform Abstract: An Additional Coordination Group Leads to Extremely Efficient Chiral Iridium Catalysts for Asymmetric Hydrogenation of Ketones.
Authors: Xie Jian‐Hua , Liu Xiao‐Yan , Xie Jian‐Bo , Wang Li‐Xin , Zhou Qi‐Lin
Published: December 2011

An efficient chiral iridium catalyst that bears a tridentate spiro P—N—N ligand catalyzes the asymmetric hydrogenation of ketones with excellent enantioselectivities and extremely high turnover numbers.
ChemInform Abstract: Carboxylation of Alkylboranes by N‐Heterocyclic Carbene Copper Catalysts: Synthesis of Carboxylic Acids from Terminal Alkenes and Carbon Dioxide.
Authors: Ohishi Takeshi , Zhang Liang , Nishiura Masayoshi , Hou Zhaomin
Published: December 2011

A broad spectrum of substrates bearing a free allyl moiety can be transformed to carboxylic acids in good to excellent yields and various functionalities are tolerated.
ChemInform Abstract: Rapid Access to α‐Alkoxy and α‐Amino Acid Derivatives Through Safe Continuous‐Flow Generation of Diazoesters.
Authors: Bartrum Hannah E. , Blakemore David C. , Moody Christopher J. , Hayes Christopher J.
Published: December 2011

Under Bamford—Stevens conditions starting from arylsulfonylhydrazones, a range of diazoesters is prepared in a flow reactor.
ChemInform Abstract: Beckmann Rearrangement of Oximes Using Pivaloyl Chloride/DMF Complex.
Authors: Narahari Srinivasa Reddy , Reguri Buchi Reddy , Mukkanti K.
Published: December 2011

The complex acts as mild and nontoxic reagent for the conversion of ketoximes into the corresponding amides within a relatively short reaction time.
ChemInform Abstract: Synthesis and Reactivity of Sulfamoyl Azides and 1‐Sulfamoyl‐1,2,3‐triazoles.
Authors: Culhane Jeffrey C. , Fokin Valery V.
Published: December 2011

The transfer reagent (IV) is formed as a stable solid which can be stored at 0—4 °C for at least 3 months without a detectable decomposition.
ChemInform Abstract: Homocoupling of Arylboronic Acids Catalyzed by Simple Gold Salts.
Authors: Matsuda Takanori , Asai Taro , Shiose Shigeru , Kato Kotaro
Published: December 2011

A convenient method including 2 different Au salts is presented for the oxidative homo‐coupling of arylboronic acids to give symmetrical biaryls in low to good yields.
ChemInform Abstract: Steric Influence of N‐Phosphorus‐arylimines on the Rhodium‐Catalyzed Asymmetric Arylation.
Authors: Hao Xinyu , Chen Qian , Yamada Ken‐ichi , Yamamoto Yasutomo , Tomioka Kiyoshi
Published: December 2011

The bulkiness of the N‐phosphorus groups at imines (I) influences both the reactivity and enantioselectivity of the rhodium/chiral amidophosphane catalyzed arylation reaction with boroxine (II).
ChemInform Abstract: A New Class of Heterogeneous Pd Catalysts for Synthetic Organic Chemistry.
Authors: Pagliaro Mario , Pandarus Valerica , Beland Francis , Ciriminna Rosaria , Palmisano Giovanni , Cara Piera Demma
Published: December 2011

4 Examples of Pd catalysts (trademarked SiliaCat Pd(0)‐hydrogels) are prepared by changing the synthetic conditions to give highly dispersed Pd nanoparticles encapsulated within an organosilica matrix (ORMOSIL).
ChemInform Abstract: Efficient Synthesis of Unsymmetric Diarylalkynes from Decarboxylative Coupling in a Continuous Flow Reaction System.
Authors: Lee Hee Joon , Park Kyungho , Bae Goun , Choe Jaehoon , Song Kwang Ho , Lee Sunwoo
Published: December 2011

Only trace amounts of symmetrical diarylalkynes are obtained in some cases as by‐ products.
ChemInform Abstract: Formation of Fluorene and Anthracene Derivatives in Reactions of Perfluorinated 1‐Alkyl‐1‐phenyl‐ and 1‐Alkyl‐2‐phenyl‐1,2‐dihydrocyclobutabenzenes with Antimony Pentafluoride.
Authors: Mezhenkova T. V. , Karpov V. M. , Platonov V. E.
Published: December 2011

The reaction of the compounds (I) and (II) under different temperatures gives different major products and also various other derivatives as by‐products.
ChemInform Abstract: Synthesis of Stereodefined Fused δ‐Hydroxy‐γ‐lactones from Dealkylative Cyclization of Epoxy‐Diesters.
Authors: Pehlivan Leyla , Jacolot Maiwenn , Coia Nicolas , Monteiro Nuno , Bouyssi Didier , Balme Genevieve
Published: December 2011

Treatment of aryl‐substituted substrates with Tms‐I or Tos‐OH produces the required lactones via dealkylative cyclization.
ChemInform Abstract: Tandem Cyclization—Michael Reaction by Combination of Metal‐ and Organocatalysis.
Authors: Aleman Jose , del Solar Virginia , Martin‐Santos Cecilia , Cubo Leticia , Ranninger Carmen Navarro
Published: December 2011

In the presence of PtCl2(dmso)2 and DABCO alkynyl malonates undergo tandem cyclization—Michael addition which allows facile access to lactones of type (III) and (V) bearing a quaternary center at C‐3.
ChemInform Abstract: Three‐Component Synthesis of Polysubstituted Pyrroles from α‐Diazoketones, Nitroalkenes, and Amines.
Authors: Hong Deng , Zhu Yuanxun , Li Yao , Lin Xufeng , Lu Ping , Wang Yanguang
Published: December 2011

If diazoacetate is used instead of the ketones (I) no products can be isolated.
ChemInform Abstract: Silver‐Catalyzed Intramolecular Chloroamination of Allenes: Easy Access to Functionalized 3‐Pyrroline and Pyrrole Derivatives.
Authors: Sai Masahiro , Matsubara Seijiro
Published: December 2011

The reaction proceeds under mild conditions and tolerates even acid‐labile functional groups.
ChemInform Abstract: A Flexible Approach to Protected (4S,5S)‐5‐Alkyl‐1‐benzyl‐4‐benzyloxy‐2‐pyrrolidinones.
Authors: Xiao Zhen‐Hua , Liu Liang‐Xian , Liu Cong , Huang Pei‐Qiang
Published: December 2011

A new reductive dehydroxylation of trans‐ enriched, diastereoisomeric α‐hydroxylactames (I) gives cis‐pyrrolidones (II) with modest to good diastereoselectivity.
ChemInform Abstract: A Facile Pathway to Enantiomerically Enriched 3‐Hydroxy‐2‐oxindoles: Asymmetric Intramolecular Arylation of α‐Keto Amides Catalyzed by a Palladium—DifluorPhos Complex.
Authors: Yin Liang , Kanai Motomu , Shibasaki Masakatsu
Published: December 2011

The method is applicable to aryl triflates bearing different aromatic and aliphatic substituents, as well as sterically hindered β‐keto amide (XII).
ChemInform Abstract: An Efficient Difluorohydroxylation of Indoles Using Selectfluor as a Fluorinating Reagent.
Authors: Lin Riyuan , Ding Shengtao , Shi Zhuangzhi , Jiao Ning
Published: December 2011

It provides a mild, convenient and regioselective approach to 3,3‐difluoroindolin‐2‐ols.
ChemInform Abstract: Tandem Reactions of 1,2,4‐Oxadiazoles with Allylamines.
Authors: Palumbo Piccionello Antonio , Pace Andrea , Buscemi Silvestre
Published: December 2011

Two novel thermal rearrangements are presented: the addition of allylamine (II) to oxadiazoles proceeds via ring‐opening followed by cycloaddition.
ChemInform Abstract: Synthesis of New Perfluoroalkylated 1,3,4‐Oxadiazoles and 1,2,4‐Triazoles Starting from 2‐(Perfluoroalkyl)ethane Thiols.
Authors: Akremi Ali , Beji Mohamed , Baklouti Ahmed
Published: December 2011

All products are purified by recrystallization.
ChemInform Abstract: AlCl3 as an Effective Lewis Acid for the Synthesis of Arylaminotetrazoles.
Authors: Habibi Davood , Nasrollahzadeh Mahmoud , Bayat Yadollah
Published: December 2011

AlCl3‐catalyzed reaction of aryl cyanamides with NaN3 affords regioselectively 1‐acyl‐5‐aminotetrazoles (II) or 5‐arylaminotetrazoles (IV) depending on the electrophilicity of the aryl substituents in the cyanamides.
ChemInform Abstract: Enantioselective Diels—Alder Reactions of Enals and Alkylidene Diketones Catalyzed by N‐Heterocyclic Carbenes.
Authors: Fang Xinqiang , Chen Xingkuan , Chi Yonggui Robin
Published: December 2011

Substrates with electron‐withdrawing groups other than ‐CO‐Ar at the α‐position of the chalcone are tested (‐CO‐O‐Et, ‐CN, ‐Ph) but fail to react.
ChemInform Abstract: Synthesis of Multifunctionalized Chromeno[2,3‐c]pyrrol‐9(2H)‐ones: Investigation and Application of Baker—Venkataraman Rearrangement Involved Reactions Catalyzed by 4‐(Dimethylamino)pyridine.
Authors: Yu Yanjun , Hu Yun , Shao Weiyan , Huang Jianing , Zuo Yinglin , Huo Yingpeng , An Linkun , Du Jun , Bu Xianzhang
Published: December 2011

A novel efficient synthesis of title chromenopyrrolones is presented.
ChemInform Abstract: Synthesis and Insecticidal Evaluation of Novel N‐Pyridylpyrazolecarboxamides Containing Different Substituents in the ortho‐Position.
Authors: Feng Qi , Yu Guanping , Xiong Lixia , Wang Mingzhong , Li Zhengming
Published: December 2011

All new N‐pyridylpyrazolecarboxamides (III), (V), (VII), (IX), (XI) and (XIII) show moderate insecticidal activities against oriental armywhorm (Mythimna separata).
ChemInform Abstract: Alkylation of 3‐Aminoisocarbostyryl Derivatives.
Authors: Potikha L. M. , Gutsul R. M. , Kovtunenko V. A. , Turov A. V.
Published: December 2011

Alkylation of title compounds predominantly proceeds at the 3‐amino group to give compounds (III).
ChemInform Abstract: An Unusual Iodocyclization: An Efficient Synthesis of Pyrimidine‐Anellated Spiro‐heterocycles.
Authors: Majumdar K. C. , Ray Krishanu , Ganai Sintu
Published: December 2011

A simple and efficient method for the synthesis of the title compounds (II) is presented via iodocyclization in the absence of any base.
ChemInform Abstract: A Carbon Material as a Strong Protonic Acid for Efficient Synthesis of 4(3H)‐Quinazolinones.
Authors: Tavakoli‐Hoseini Niloofar , Davoodnia Abolghasem
Published: December 2011

The employed catalyst can be used three times without significant loss of activity.
ChemInform Abstract: Direct Synthesis of Chiral 1,2,3,4‐Tetrahydropyrrolo[1,2‐a]pyrazines via a Catalytic Asymmetric Intramolecular Aza‐Friedel—Crafts Reaction.
Authors: He Yuwei , Lin Maohui , Li Zhongmin , Liang Xinting , Li Guilong , Antilla Jon C.
Published: December 2011

A new, efficient, and enantioselective method to prepare a number of title pyrrolopyrazines is reported.
ChemInform Abstract: Three‐Component Condensation of 4‐Aryl‐1,4‐dihydrobenzo[4,5]imidazo[1,2‐a][1,3,5]triazin‐2‐amines with Formaldehyde and Primary Amines.
Authors: Potapov A. Yu. , Shestakov A. S. , Verezhnikov V. N. , Shikhaliev Kh. S.
Published: December 2011

The title reaction of triazine (V) proceeds with elimination of pyridinecarbaldehyde.
ChemInform Abstract: Facile Synthesis of 4H‐1,2,4‐Benzothiadiazine‐1,1‐dioxides.
Authors: Cherepakha Artem , Kovtunenko Vladimir O. , Tolmachev Andrey , Lukin Oleg , Nazarenko Konstantin G.
Published: December 2011

No column chromatography is necessary to purify the respective product.
ChemInform Abstract: Direct Conversion of Pinacol Arylboronic Esters to Aryl Triolborates.
Authors: Li Gao‐Qiang , Kiyomura Shunsuke , Yamamoto Yasunori , Miyaura Norio
Published: December 2011

A simple and practical method which is compatible with various functional groups for the synthesis of the stable compounds (III) and (V) is described.
ChemInform Abstract: Copper‐Catalyzed β‐Boration of α,β‐Unsaturated Carbonyl Compounds with Tetrahydroxydiborane.
Authors: Molander Gary A. , McKee Silas A.
Published: December 2011

The method can be applied to a broad spectrum of substrates to produce synthetically important boron agents.
ChemInform Abstract: Reaction of N,N‐Disubstituted Perfluoroalkanethioamides with Trialkyl Phosphites. A New Method for the Synthesis of Polyfluorinated α‐Aminophosphonates.
Authors: Mykhaylychenko Sergiy S. , Pikun Nadiia V. , Shermolovich Yuriy G.
Published: December 2011

The reaction of thioamides (I) and (V) with trialkyl phosphites affords vinyl phosphonates, probably via intermediates of type (IV).
ChemInform Abstract: Convenient Synthesis of Fluoroalkyl α‐ and β‐Aminophosphonates.
Authors: Roeschenthaler Gerd‐Volker , Kukhar Valery P. , Kulik Irene B. , Sorochinsky Alexander E. , Soloshonok Vadim A.
Published: December 2011

The addition of alkyl phosphites (II) or the α‐carbanion of phosphonate (V) to aldimines (I) provides access to fluoroalkyl aminophosphonates (IV) and (VII), respectively.
ChemInform Abstract: Silica Gel‐Immobilized Aluminum Phthalocyanine Complex as a Heterogeneous Catalyst for the Synthesis of α‐Amino Phosphonates.
Authors: Matveeva E. D. , Shuvalov M. V. , Zefirov N. S.
Published: December 2011

Aluminum phthalocyanine complexes immobilized onto silica gel exhibit high catalytic activity and stability in the Kabachnik—Fields reaction.
ChemInform Abstract: Effective Application of Heavy Fluorous Thioglycoside for Oligosaccharide Synthesis.
Authors: Goto Kohtaro , Nuermaimaiti Nueramina , Mizuno Mamoru
Published: December 2011

The synthesis of the novel heavy fluorous thioglycoside (III) and its application as glycosyl donor is presented.
ChemInform Abstract: Regio‐ and Stereoselective Synthesis of 2‐Deoxy‐C‐aryl Glycosides via Palladium—Catalyzed Decarboxylative Reactions.
Authors: Xiang Shaohua , Cai Shuting , Zeng Jing , Liu Xue‐Wei
Published: December 2011

The reaction of benzoic acids substituted with strong electron‐donating groups at the 2,4‐ or 2,6‐ position succeeds with high yields in a short times.
ChemInform Abstract: A Fully Palladium‐Mediated Construction of Phenanthrenes and Naphthoxindoles.
Authors: Nassar‐Hardy Luma , Deraedt Christophe , Fouquet Eric , Felpin Francois‐Xavier
Published: December 2011

A three‐step synthesis of naphthoxindole alkaloids (V) is presented, involving a Pd‐catalyzed direct intramolecular C—H arylation as key step.
ChemInform Abstract: Pseuduvarines A and B, Two New Cytotoxic Dioxoaporphine Alkaloids from Pseuduvaria rugosa.
Authors: Taha Hairin , Hadi A. Hamid A. , Nordin Noraziah , Najmuldeen Ibrahim A. , Mohamad Khalit , Shirota Osamu , Nugroho Alfarius E. , Piow Wong Chin , Kaneda Toshio , Morita Hiroshi
Published: December 2011

Pseuduvarines A (Ia) and B (Ib) show cytotoxicity against the human cancer cell lines MCF7, HepG2, and HL‐60.
ChemInform Abstract: Synthesis and anti‐HIV Evaluation of 3′‐Triazolo Nucleosides.
Authors: Roy Vincent , Obikhod Aleksandr , Zhang Hong‐Wang , Coats Steven J. , Herman Brian D. , Sluis‐Cremer Nicolas , Agrofoglio Luigi A. , Schinazi Raymond F.
Published: December 2011

A series of title compounds of type (I) and (II) are tested for their anti‐HIV activities.
ChemInform Abstract: Design, Synthesis and Antibacterial Activity of Novel Ketolides Bearing an Aryltetrazolyl‐Substituted Alkyl Side Chain.
Authors: Song Qiu‐Ling , Guo Bao‐Qin , Zhang Wen , Lan Ping , Sun Ping‐Hua , Chen Wei‐Min
Published: December 2011

A series of novel C‐11,12 cyclic carbamate ketolides (17 examples) are synthesized from clarithromycin and evaluated for their antibacterial activities.
ChemInform Abstract: Biosynthetic Capacities of Actinomycetes. Part 59. Elaiomycins B (I) and C (II), Novel Alkylhydrazides Produced by Streptomyces sp. BK190
Authors: Kim Byung‐Yong , Willbold Stefanie , Kulik Andreas , Helaly Soleiman E. , Zinecker Heidi , Wiese Jutta , Imhoff Johannes F. , Goodfellow Michael , Suessmuth Roderich D. , Fiedler Hans‐Peter
Published: December 2011

physico‐chemical properties and cytotoxicity
ChemInform Abstract: Atom‐Economic and Stereoselective Syntheses of the Ring A and B Subunits of the Bryostatins.
Authors: Trost Barry M. , Yang Hanbiao , Brindle Cheyenne S. , Dong Guangbin
Published: December 2011

Diverse methods are presented to obtain stereo‐ and chemoselectively the title subunits.
ChemInform Abstract: The Natural Product CCR5 Antagonist Anibamine and Its Analogues as Antiprostate Cancer Agents.
Authors: Haney Kendra M. , Zhang Feng , Arnatt Christopher K. , Yuan Yunyun , Li Guo , Ware Joy L. , Gewirtz David A. , Zhang Yan
Published: December 2011

Based on the novel structural skeleton of anibamine, a series of analogues is designed and synthesized.
ChemInform Abstract: Synthesis and Insecticidal Activities of Novel 1,3,4‐Thiadiazole 5‐Fluorouracil Acetamides Derivatives: An RNA Interference Insecticide.
Authors: Wan Rong , Zhang Jian‐Qiang , Han Fen , Wang Peng , Yu Peng , He Qiu
Published: December 2011

18 Title compounds of type (I) are evaluated for their insecticidal activities.
ChemInform Abstract: Development of a Highly Selective Fluorescence Probe for Alkaline Phosphatase.
Authors: Kawaguchi Mitsuyasu , Hanaoka Kenjiro , Komatsu Toru , Terai Takuya , Nagano Tetsuo
Published: December 2011

TokyoGreen‐methyleneoxy phosphate (I)(TG‐mPhos) is the first fluorescence probe that shows selectivity for alkaline phosphatase (ALP) over protein tyrosine phosphatase and protein serine/threonine phosphatase.
ChemInform Abstract: Retention of Palladium and Phosphine Ligands Using Nanoporous Polydicyclopentadiene Thimbles
Authors: Gupta Abhinaba , Long Tyler R. , Rethwisch David G. , Bowden Ned B.
Published: December 2011

Thimbles composed of polydicyclopentadiene retain Pd catalyst and phosphine ligands used in Buchwald—Hartwig and Sonogashira coupling reactions but allow the products to permeate.
ChemInform Abstract: Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production.
Authors: Sexton Karen E. , et al. et al.
Published: December 2011

Pantolactam androgen receptor antagonists are identified by using an iterative library design.
ChemInform Abstract: Rational Design of Microporous and Mesoporous Solids for Catalysis: From the Molecule to the Reactor
Authors: Louis Benoit , Laugel Guillaume , Pale Patrick , Pereira Marcelo Maciel
Published: December 2011

Review: 123 refs.
ChemInform Abstract: Mesocrystals: Syntheses in Metals and Applications
Authors: Fang Jixiang , Ding Bingjun , Gleiter Herbert
Published: December 2011

Review: 70 refs.
ChemInform Abstract: Pd‐Mediated Reactions of Epoxides
Authors: Muzart Jacques
Published: December 2011

Review: about 200 refs.
ChemInform Abstract: Ferrocene and Half Sandwich Complexes as Catalysts with Iron Participation
Authors: Peters Rene , Fischer Daniel F. , Jautze Sascha
Published: December 2011

Review: 117 refs.
ChemInform Abstract: Fe‐Catalyzed Oxidation Reactions of Olefins, Alkanes, and Alcohols: Involvement of Oxo‐ and Peroxo Complexes
Authors: Schroeder Kristin , Junge Kathrin , Bitterlich Bianca , Beller Matthias
Published: December 2011

Review: 164 refs.
ChemInform Abstract: Reactivity Control by Calixarenes
Authors: Mandolini Luigi , Cacciapaglia Roberta , Di Stefano Stefano
Published: December 2011

Review: 54 refs.
ChemInform Abstract: Concave Reagents
Authors: Luening Ulrich
Published: December 2011

Review: 129 refs.
ChemInform Abstract: Amino Acid Ligand Chirality for Enantioselective Syntheses
Authors: Micskei Karoly , Patonay Tamas , Caglioti Luciano , Palyi Gyula
Published: December 2011

Review: 112 refs.
ChemInform Abstract: Chiral Salen Complexes
Authors: Zhang Wen‐Zhen , Lu Xiao‐Bing
Published: December 2011

Review: 121 refs.
ChemInform Abstract: Our Contribution to Stable Carbene Chemistry
Authors: Martin David , Melaimi Mohand , Soleilhavoup Michele , Bertrand Guy
Published: December 2011

Review: 231 refs.