bluuebunny/crossref_metadata_2025 huggingface dataset:
Coal quality, mineralogy, petrography, and geochemistry of the high-strontium Parçikan lignite
Authors: OSKAY Rıza Görkem , KARAYİĞİT Ali İhsan
Published: November 2022

The Parçikan coalfield hosts a late Miocene 1.1-m thick coal seam. This study aims to determine coal quality, mineralogy, petrography and geochemistry, and controlling factors of elemental enrichments. The coals are generally black and greyish black in colour, and the low part of the seam commonly includes fossil shell remains. The ash yield displays a decreasing trend towards the upper part of the seam; in turn, gross calorific and total C values increase upwards. The total S content being generally higher than 5% (on dry basis), displays an increasing trend towards the upper part. In the entire seam, huminite is the most common maceral group, while inertinite and liptinite display variable proportions. The identified minerals by XRD are mainly quartz, clay minerals, calcite, pyrite, and aragonite (in fossil shell remains-bearing samples), whereas feldspars and marcasite determined in a few samples. Furthermore, in the coal samples, celestine and barite were identified by SEM-EDX. This study indicates that precipitation of celestine and Sr-bearing barite grains during diagenetic stage and Sr-uptake by mollusc within the palaeomire caused Sr enrichment in the entire seam. Overall, the water influx and redox conditions controlled the mineralogical and the elemental compositions of the coal seam.
What Type of Oral Corrective Feedback do Chilean EFL Young Learners Prefer?
Authors: Aedo Pablo , Millafilo Claudia
Published: November 2022

This article presents the perspectives of a Chilean group of young learners of English as a foreign language with respect to the types of corrective oral feedback when making a spoken mistake and the reasons for their preferences. By means of a qualitative exploratory study, the views of 20 students were collected through a specially adapted scale and a focus group. The data from the scales were analyzed with descriptive statistics while the focus groups were interpreted with the content analysis technique. The results suggest that students appreciate teacher’s correction and feedback when done carefully and clearly and considering students’ affective domains such as beliefs and motivation. They also show a tendency towards the strategies of recast and repetition. On the other hand, they prefer less the use of metalinguistic feedback and elicitation strategies. In addition, this experience suggests that children are capable of reflecting on their learning processes, so it is urged that children be given an active participatory role in the development of methodologies and strategies to capture the voices of the real potential beneficiaries of these.
Karakteristik Lesi dan Faktor-Faktor Pemicu Penderita Stomatitis Aftosa Rekuren pada Mahasiswa Profesi Kedokteran Gigi USU Tahun 2019-2020
Authors: Darwis Aida Fadhilla , Lailani Dania
Published: November 2022

Recurrent Aphthous Stomatitis (RAS) is ulcer in the oral mucosa that occur repeatedly with unknown etiologic factors but varied trigger factors and lesion characteristics. The prevalence of RAS still high in community, however pain and the recurrence impact the quality of life both in oral activities and daily activities such as: avoided brushing teeth that it causes poor oral conditions, impaired mastication, swallowing, speaking, feeling uncomfortable, difficulty sleeping and reducing social interaction. The purpose of this study was to determine the frequency distribution of lesion characteristics and the triggering factors for patients with recurrent aphthous stomatitis in USU dental professional students in 2019-2020. This research is a survey study with a cross sectional design. The population is students of the dental profession at the University of North Sumatra in 2019-2020 with a total sample of 62 respondents who were used as research subjects. Measurement of SAR variables using the Recurrent Aphthous Stomatitis Diagnosis (RASDX) questionnaire. The research data was obtained by distributing online questionnaires in the form of a google form. Students who were most affected by SAR were female at 87.1%. The most common type of SAR found was minor at 95.2%, was in the labial mucosa by 72.6%, single ulcers of 95.2%), history of ulcer duration suffered by respondents was around 7-14 days 54.8%, multifactorial triggering factors are genetic, trauma and stress (30,6%) with the most common triggering factor was stress at 93.5%. The characteristics RAS in this research were minor type on the labial mucosa, a single of number and duration of 7-14 days. Based on the trigger factors, it can be concluded that the most common group of 3 multifactor (genetic, trauma and stress) which stress is the most common factors.
Saliva sebagai Media Diagnosis untuk Deteksi Keganasan
Authors: Arinawati Dian Yosi , Widyawati Aprilinda
Published: November 2022

Human saliva is a potential diagnostic fluid where most of changes in the body can be reflected in saliva and it considered a "mirror of the body". Currently, salivary biomarkers help in the detection of oral cancer, dental caries, periodontal disease, diabetes, breast cancer, and lung cancer. Saliva like others body liquid in human body such as urine and blood contain tumour derived biomarkers i.e DNA, asam amino, cells and vesicles which shed via bloodstream and secreted through salivary gland. Salivary diagnostic is a growing dynamic field utilizing nanotechnology and molecular diagnostics to aid in the diagnosis of oral and systemic diseases. The purpose of this review is to determine saliva as a diagnostic medium through various its biomarkers to detect malignancies in the body. The use of saliva as a medium for molecular diagnosis has the advantage of being sensitive, specific, can be used as a screening medium in diagnosing and staging, therefore usefull for early detection of malignancy, for example Oral Squamous Cell Carcinoma can be seen in three levels, changes in cellular DNA, altered mRNA transcripts, altered protein levels (intracellular or extracellular). It can also detect other cancers such as Salivary Gland Cancer, and even in parts of the body far from the oral cavity such as Lung Cancer, Pancreatic Cancer, Breast Cancer. It can be concluded that saliva can be used as a non-invasive diagnostic medium to detect various oral and systemic malignancies.
Potensi Pasta Gigi Minyak Atsiri Temulawak (Curcuma xanthorriza Roxb) dalam Menghambat Pembentukan Plak dan Gingivitis pada Tikus yang Diinduksi Phorpyromonas gingivalis
Authors: Nurhadi Yumnaina , Lestari Pujiana Endah , Pujiastuti Peni
Published: November 2022

Gingivitis is an inflammatory disease in gingiva without any loss of attachment caused by plaque. Gingivitis is reversible, if not treated it can develop into periodontitis. Gingivitis-causing bacteria include Phorpyromonas gingivalis, acting as secondary bacteria in plaque formation at the secondary colonization stage by attaching themselves to monolayers that have been formed by primary bacteria. Herbal use in Indonesia is still a trend until now with the slogan back to nature, one of the easy to find and useful is essential oil from curcuma rhizomes containing xanthorrizol and curcumin. They are antibacterial that can inhibit the formation of plaques that cause gingivitis. The purpose was to analyze the potential of curcuma essential oil toothpaste in inhibiting the formation of plaque and gingivitis. 27 wistar mice were divided into 9 groups, namely negative control group, positive control, treatment applied curcuma essential oil toothpaste concentration of 0.5%, 1%, 2%, 4%, 8%, 16% and 32%. Each mouse induced P. gingivalis 0.02 ml on molar sulkus one and two, 24 hours later performed tooth brushing with toothpaste according to the group, the next 24 hours were observed in day 3, 5 and 7 using plaque index according to Park and Katz and gingiva index according to Lee. Treatment and observation are carried out 3 repetitions. The results of the plaque index score and gingiva index in the treatment group were fewer than the negative controls. Curcuma essential oil toothpaste can inhibit the formation of plaque and gingivitis by decreasing the plaque index and gingiva index in P. gingivalis- induced wistar mice.
Jumlah Sel Osteoklas pada Tulang Alveolar Daerah Tekanan Gigi Tikus yang Diinduksi Gaya Mekanis Ortodonti
Authors: Arrahma Samahi , Herniyati Herniyati , Prijatmoko Dwi
Published: November 2022

The mechanical force of orthodontics produces areas of pressure and pull. In the pressure area occurs resorption of alveolar bones carried out by osteoclast cells. The study aims to find out the change in the number of osteoclast cells in the alveolar bone pressure area of mouse teeth that induced mechanical force orthodontics. 36 male rats are divided into 6 groups. Group K: mice are not given a mechanical style of orthodontics. Group P: mechanically styled orthodontics (GMOs). GMOs in mice were administered to the upper jaw molar-1 (M-1) teeth (RA) right and in both RA incisive teeth using Ni-Ti Orthodontic Closed Coil Spring diameter 0.01 inches in orthodontic force of 3.5 oz = 85.05 gr/cm2 = 10 grF for 1 week, 2 weeks and 3 weeks. The results of the study were 1 week (1.99), 2 weeks (1.92), and 3 weeks (1.75). Conclusion of mechanical administration of orthodontic force increases the number of osteoclast cells on the 8th day (1 week), the 15th (2 weeks), and the 22nd (3 weeks). Based on the observation time there was a decrease in the number of osteoclast cells from 1 week to 2 weeks then to 3 weeks but not significant.
Dimenzije mehanizacije in vozil, ki se gibljejo po slovenskih gozdovih zunaj gozdnih cest
Authors: Saražin Jaša , Dolenšek Marjan
Published: November 2022

The Forest Act allows vehicles to be driven in the forest outside of forest roads for the purpose of forest management or rescue of persons or property. The vehicles and machinery intended for these tasks are very diverse, both in their form and in the dimensions and quality requirements of the thoroughfares on which they move. The types of mechanization discussed include agricultural tractors, specialized forestry mechanisation, trailers on tractors, trucks, cars and construction machinery. By reviewing various databases, legal restrictions and our own experience, interval data on the mass and width of representative examples of each category were given. It was estimated that among forest owners, the most numerous mechanization was up to 200 cm wide, while among professional contractors and protection and rescue forces, the most numerous mechanization and vehicles were up to 230 cm wide. It was also found that mechanization and vehicles up to 230 cm wide can perform all forest management and protection and rescue tasks at least on a basic scale.
Episodios psicóticos inducidos por ayahuasca: revisión sistemática a partir de un caso.
Authors: Alcantarilla Laura , García-Alcarria Enrique , Almonacid Celia
Published: November 2022

La ayahuasca pertenece al grupo de alucinógenos de origen vegetal con los que comparte su capacidad de alterar el estado de conciencia y provocar alteraciones perceptivas. Empleada tradicionalmente en forma de brebaje en ritos ceremoniales con el propósito de alcanzar experiencias de contenido espiritual o sanatorio, su uso se ha extendido a lo largo de centurias hasta nuestro actual contexto cultural dentro del cual es empleada por pequeños grupos guiados por fines de crecimiento personal. La experiencia suele durar unas horas y los efectos suelen ser autolimitados. Se describe el caso clínico de una paciente que, tras el consumo experimental de ayahuasca, desarrolla un episodio maníaco con síntomas psicóticos. Se realiza asimismo una búsqueda sistemática de casos publicados de sintomatología psicótica relacionada con el consumo de ayahuasca. A nivel experimental, la relación entre ayahuasca y experiencias psicóticas es poco conocida, si bien se ha determinado un buen perfil de seguridad de la sustancia en administraciones puntuales en sujetos sanos. En el presente estudio, los resultados sugieren que la aparición de episodios psicóticos asociados con consumo de ayahuasca es un fenómeno infrecuente que parece estar relacionado con características de vulnerabilidad tales como historia personal o familiar de trastorno mental grave o el uso concomitante de otros compuestos tóxicos o drogas, especialmente cannabis.
Enfermedad de Behcet: Manifestaciones neurológicas y psiquiátricas observadas en dos pacientes en el Hospital Nacional Dos de Mayo (Lima, Perú).
Authors: Castañeda Marco A. , Durán Espinoza César , Peña Carlos Saúl
Published: November 2022

Se describen las manifestaciones neurológicas y psiquiátricas de dos pacientes con características clínicas de la enfermedad de Behcet, observados a lo largo de varias décadas. Se ilustra con imágenes la presencia de aftas orales y genitales recidivantes. Uno de ellos desarrolló trombosis de la vena femoral y en ambos hubo presencia de eritema nodoso. La evaluación oftalmológica determinó ausencia de uveitis en ambos pacientes y ceguera por maculopatía distrófica monocular sin signos de vasculitis retinal en la paciente mujer. Exámenes de laboratorio en sangre y en el líquido cerebro espinal evidenciaron pleocitosis linfocítica. El test cutáneo de patergia fue negativo. Asimismo, se determinó la ausencia de hallazgos compatibles con otras enfermedades autoinmunes. Durante el periodo de evaluación se correlacionaron las manifestaciones clínicas y los hallazgos en tomografía (TM) y resonancia magnética cerebral (RMC). Se explica igualmente la mielitis recidivante y su correlato con los resultados de la resonancia magnética medular (RMM). El tiempo de evaluación y seguimiento por consulta externa y durante la hospitalización en el paciente varón (73 años), que inició la enfermedad a los 35 años, fue de 34 años; la paciente mujer (50 años, inició su enfermedad a los 28 años y fue seguida por espacio de 8 años. Este proceso permitió comprender los diferentes factores mórbidos que influyeron en la grave evolución del cuadro clínico estudiado.
Study of biological markers in skin quality treatment by subcutaneous injection of a stabilized composition of 26 mg/mL of high molecular weight HA
Authors: Bon Bétemps Jérémie , Gavard Molliard Samuel , Hadjab Basste , Badi Mhd , Ghazal Anas , Cerrano Marco
Published: November 2022

Aim: Hyaluronic acid (HA) injectables have gained rapid acceptance for the treatment of skin rejuvenation. A novel HA/sorbitol composition intended for skin quality improvement containing 2.6% of high molecular weight HA stabilized by sorbitol was recently designed to be injected subcutaneously. The aim of this study was to assess the expression of biological markers of skin quality after administration of the composition. Methods: The HA/sorbitol composition was evaluated after injection into the superficial adipose tissue with ex vivo cultured human skin explants versus a product comparator to study the general morphology of the skin tissues and the expression of HA, elastin, collagen type I, collagen type III, and fibrillin-1 in the dermal layer. Results: The results demonstrate that the HA/sorbitol composition is able to boost the production of HA, elastin, collagen type I, collagen type III, and fibrillin-1 in the dermis while providing a proper quality of skin morphology. Conclusion: The HA/sorbitol composition improved biological markers of skin quality in the dermis after product injection into the superficial adipose tissue. This novel composition can be considered as an attractive solution to treat skin aging by injecting a specific HA/sorbitol formulation to strategically target the subcutaneous tissue to improve the quality of the different layers of the skin.
Neck Circumference in Combination with Biochemical Variables as a Surrogate Marker of NAFLD: The FLiO Study
Authors: Elorz Mariana , Benito Alberto , Marin Berta Araceli , Perez del Campo Nuria , Herrero Jose Ignacio , Monreal Ignacio , Tur Josep , Martínez J. Alfredo , Zulet María Ángeles , Abete Itziar
Published: November 2022

Neck circumference (NC), neck circumference to height ratio (NHtR) and neck circumference to weight ratio (NWtR) appear to be good candidates for the non-invasive management of non-alcoholic fatty liver disease (NAFLD). This study aimed to evaluate the ability of routine variables to assess and manage NAFLD in participants with obesity and NAFLD included in a 2-year nutritional intervention program. Anthropometric measurements, biochemical variables and imaging techniques were performed at different study time-points (baseline, 6, 12 and 24 months). The nutritional intervention significantly improved all anthropometric measurements as well as the glucose profile and the hepatic enzymes. NC and neck ratios combined with ALT levels and HOMA-IR showed good prediction ability for the hepatic fat content and hepatic steatosis at all the study time-points in a ROC analysis. The prediction ability of the combination panels improved when the weight loss variable was also considered. NC and neck ratios are easy anthropometric measurements that in combination with routine biochemical variables (ALT and HOMA-IR) showed good prediction ability of NAFLD. More research studies are necessary to validate the utility of these simple and easy variables as surrogate markers of NAFLD since their application could improve the prevention and management of this prevalent disease.
Nano-Theranostics Approaches and Mitochondrial Targeted Drug Delivery: Alzheimer ’s Disease Therapeutic Interventions
Authors: Chacko Leena , Nag Sagnik , Dewanjee Saikat , Ghosh Subhrojyoti , Vallamkondu Jayalakshmi , Mitra Oishi , Dey Anuvab , Bhuniya Tiyasa , Paluru Hari Prasad Reddy , Reddy P. Hemachandra , Kandimalla Ramesh
Published: November 2022

One of the most frequent brain diseases, Alzheimer's is defined by poor cognitive function brought on by the build-up of Beta Amyloid plaques and the gradual death of neurons. Glucose metabolism and the development of amyloid plaques are being studied together. Under physiologically normal circumstances, glucose is the primary substrate for the adult human brain. The prodromal phases of AD are significantly influenced by glucose hypometabolism. Hypometabolism of glucose in the brain is a clear sign of mitochondrial dysfunction and bioenergetic system impairment. By regulating energy synthesis and cell death, mitochondria play a crucial role in the functioning of cells. Increased formation of reactive oxygen species (ROS) and oxidative stress are a result of mitochondrial dysfunction, which also accelerates the development of Alzheimer's disease. For the maintenance of balance, autophagy is crucial because it selectively destroys damaged mitochondria. AD affects this route for mitochondrial breakdown. Targeting specific mitochondrial ligands by interventions along this pathway might be a useful therapeutic approach. Due to a number of biological obstacles, this method has significant limitations. As a result, many nanocarriers have been created to improve drug delivery effectiveness. All potential nanotechnology-based treatments for AD have been examined in this study, with a particular emphasis on medication delivery to the mitochondria
SAUSA: Securing Access, Usage, and Storage of 3D Point Clouds Data by a Blockchain-based Authentication Network
Authors: Xu Ronghua , Chen Yu , Chen Genshe , Blasch Erik
Published: November 2022

The rapid development of three-dimensional (3D) acquisition technology based on 3D sensors provides a large volume of data, which is often represented in the form of point clouds. Point cloud representation can preserve the original geometric information along with associated attributes in a 3D space. Therefore, it has been widely adopted in many scene-understanding-related applications such as virtual reality (VR) and autonomous driving. However, the massive amount of point cloud data aggregated from distributed 3D sensors also poses challenges for secure data collection, management, storage, and sharing. Thanks to the characteristics of decentralization and security nature, Blockchain has a great potential to improve point cloud services and enhance security and privacy preservation. Inspired by the rationales behind Software Defined Network (SDN) technology, this paper envisions SAUSA, a blockchain-based authentication network that is capable of recording, tracking, and auditing the access, usage, and storage of 3D point cloud data sets in their life-cycle in a decentralized manner. SAUSA adopts an SDN-enabled point cloud service architecture which allows for efficient data processing and delivery to satisfy diverse Quality-of-Service (QoS) requirements. A blockchain-based authentication framework is proposed to ensure security and privacy preservation in point cloud data acquisition, storage, and analytics. Leveraging smart contracts for digitizing access control policies and point cloud data on the blockchain, data owners have full control of their 3D sensors and point clouds. In addition, anyone can verify the authenticity and integrity of point clouds in use without relying on a third party. Moreover, SAUSA integrates a decentralized storage platform to store encrypted point clouds while recording references of raw data on the distributed ledger. Such a hybrid on-chain and off-chain storage strategy not only improves robustness and availability but also ensures privacy preservation for sensitive information in point cloud applications. A proof-of-concept prototype is implemented and tested on a physical network. The experimental evaluation validates the feasibility and effectiveness of the proposed SAUSA solution.
Aging-Related Decline in Phonated and Whispered Speech Perception Not Compensated for by Increased Duration and Intensity: Evidence from Mandarin-Speaking Adult Listeners
Authors: Xu Min , SHAO Jing , Liu Boquan , Wang Lan , Ding Hongwei , Zhang Yang
Published: November 2022

Purpose: This study aimed to examine how aging and modifications of critical acoustic parameters may affect the perception of whispered speech as a degraded signal. Method: Forty Mandarin-speaking adults were included in the study. Part 1 of the study compared the perception of Mandarin lexical tones, vowels, and syllables in older and younger adults in whispered vs. phonated speech conditions. Parts 2 and 3 further examined how modification of duration and intensity cues contributed to the perceptual outcomes. Results: Perception of whispered tones was compromised in older and younger adults. Older adults identified lexical tones less accurately than their younger counterparts, particularly for phonated T2, T3 and whispered T3. Aging also negatively affected the vowel identification of /i, u/ in the whispered condition. Syllable-level accuracy was largely dependent on the accuracy of lexical tones and vowels. Furthermore, reduced duration led to the decreased accuracy of phonated T3 and whispered T2, T3 but increased accuracy of phonated T4. Reduced intensity lowered the recognition accuracy for phonated vowels /i, ɤ, o, y/ in older adults and /i, u/ in younger adults, and it also lowered the accuracy of whispered vowels /a, ɤ/ in older adults. Contrary to our expectation, increased duration and intensity did not improve older adults’ speech perception in either phonated or whispered conditions. Conclusion: The results suggest that aging adversely affected speech perception in both phonated and whispered conditions with more challenges in identifying whispered speech for older adults. While older adults’ diminished performance may be potentially due to problems with processing the degraded temporal and spectral information of the target speech sounds, it cannot be simply compensated for by increasing the duration and intensity of the target sounds beyond the audible level.
Forward Modelling on Gravity Anomalies Fault Model Using MATLAB Mathworks
Authors: Adhani Alika Tabriza , Anggitarizka Mega , Meidina Zahrah , Wibowo Rahmat Catur
Published: November 2022

The gravity method is one of the geophysical methods utilized to determine the subsurface conditions of the earth according to differences in rock mass density below the surface. In the exploration of gravity requires an initial description as a reference for measurement. The synthetic modelling carried out this time is a forward modelling of fault anomalies carried out with the help of Grav2dc and Matlab Mathworks software. This study aims to compare the results of synthetic modelling using Grav2dc software and Matlab Mathworks as well as to test whether the program built can run well or not. The model parameters utilized are the density value of 1 kg/m3 with a deep plate depth of 50 m, a shallow plate depth of 150 m and the location of the fault at a depth of 150 m with a thickness of 40 m. The data processing in this study used two pieces of software, are Grav2dc and Matlab MathWorks to compare and test whether the processing results using Matlab MathWorks software were in accordance with the synthetic model processed using Grav2dc software. The results obtained from this study are the fault model obtained from processing using Matlab MathWorks and Grav2dc software with model parameters in the form of density and depth, where density and depth have a role in shaping the value of the change in gravity.
Investigating Seasonal Variations of Soil Thermal Properties (STPs) Under Different Land Use Patterns in Abeokuta, Southwest Nigeria
Authors: Gainiyu Saheed Adekunle , Shobowale Oluwafemi  Ayomide , Sikiru Yaya Korede
Published: November 2022

Soil thermal properties (STPs) command the storage and transfer of thermal energy through the soil matrix, which can be changed by land use systems and seasonal changes. Depiction of STPs based on land uses and seasonal changes eases better understanding of trend of periodic disparity of soil heat flux across varied land use practices. This study assesses the seasonal and land use prompted variability of STPs such as thermal conductivity (λs), thermal resistivity (TR), specific heat capacity (Cs), thermal diffusivity (TD) and temperature of sandy loam topsoils under different land uses: Dumpsite (DS), block-making site (BMS), abattoir site (ABS), and grassland (GL). Seasonal changeability of the STPs was determined by two reiterations of aforementioned STPs measurements during the wet (April/May, 2019) and dry (January/February, 2020) seasons. The STPs were measured in situ utilizing KD2 Pro Thermal Analyzer. The research discloses that STPs are impacted by land use substantially. All the observed STPs were not differ significantly among the studied land uses during the wet season. However, statistically substantial variations in Cs and TD of topsoils under all investigated land uses were recognized during the dry season. Moreover, no significant alteration in the mean soil temperature was observed among the sampling land uses during the dry season. The result of the present study inspires more studying the seasonal changeability of STPs based on a more agricultural and economically related land uses as well as broad sampling design to account for their spatial changeability. The findings of this study will assist land users to make best choice of appropriate land management practices for viable agriculture and environmental management.
Analysis of Productivity Synchronization of Barge Transportation Equipment and Crane Loading on Nickel Ore Delivery Activities in PT. Antam Nickel UBP North Maluku
Authors: Haya Fitria Dwi Ningsi , Jolo Aliyusro , Yanny Yanny
Published: November 2022

Nickel mining activities at PT. ANTAM North Maluku Nickel UBP is closely related to the production and distribution process. To achieve optimal production, nickel ore is loaded or shipped in accordance with the company's production targets. The study aims to determine the compatibility value of barges and crane loading equipment in the shipping process and to determine the factors that affect the productivity of nickel ore shipments. The research method used is descriptive quantitative method, where the analysis process is based on distribution table data, average values, ​​and percentages. This research was conducted at the Tanjung Buli Site in the MV. shipping process. Lumoso Karunia VIII. In this shipment, the stowage plan target is 55255 tons which must be completed within a maximum of 10 days. The results of the calculation of the compatibility of crane loading equipment in MV. Lumoso Karunia VIII and barge transportation have a match factor value of 0.72 or <1. Factors that affect the decline in the shipping process are work efficiency time, the value of the match factor and rainy time. From the calculation results, the work efficiency time obtained is 65.94% or less efficient. The value of the match factor <1 can conclude that the transportation equipment is busy while the loading equipment has a lot of idle time and rain constraints with an average amount of rain time of 206.6 minutes or 3.44 hours. However, the shipping process can reach the production target within 8 days with the capability of loading equipment productivity reaching 6997.95 tons/day.
Sentiment Analysis of Covid-19 Vaccination Policy in Indonesia
Authors: Zaky Ahmad , Kusumastuti Retno
Published: November 2022

In December 2020, the COVID-19 pandemic had lasted for 10 months in Indonesia and there was no way out of the pandemic. A glimmer of hope came from President Joko Widodo in August 2020 when he said that the vaccination program would start in January 2021 and the vaccine had arrived in Indonesia in December 2020. Various responses have emerged in the community regarding the vaccination policy, especially on social media. Public trust in a policy is one of the factors driving a successful policy. This article shows how the public's sentiment is towards the covid-19 vaccination policy by conducting text mining on netizen comments on YouTube social media, analyzes the sentiment from citizens, and analyzes the topics discussed about the covid-19 vaccination policy. The results showed that the majority of netizens had negative sentiments about the covid-19 vaccination policy with concerns, among others, about vaccine safety issues and the potential for corruption from the policy. To increase public confidence in the covid-19 vaccination policy, the government must answer them. Concerns about vaccine safety can be overcome by giving an example of a high government official of being willing to be vaccinated beforehand and live broadcast as was done by the elected president and vice president of the United States Joe Biden and Kamala Harris. Meanwhile, concerns over the potential for corruption can be resolved by taking more transparent, accountable and responsive actions in implementing the vaccination policy.
Collaborative Governance dalam Implementasi Perda tentang Pengawasan, Pengendalian Peredaran dan Penjualan Minuman Beralkohol di Kabupaten Sukoharjo
Authors: Nurharjadmo Wahyu , Nurhayati Ika
Published: November 2022

Sukoharjo Regency is an area that has been a center for the production of local alcoholic beverages which has been carried out for generations. To overcome the possible impact that is not implemented, the regional government issues a regional regulation that regulates the supervision, control of circulation and sales of alcoholic beverages. In its implementation, the government cannot run alone. In addition to the relevant government agencies, it is necessary to involve parties outside the government through a collaborative governance approach. However, even this process is not easy. Various obstacles can arise for various reasons, considering that there are still many people as producers who depend on this business for their livelihood.
Neofobia generalizada: concepto, modelo teórico y medición
Authors: Barraza Macías Arturo
Published: November 2022

Objective: To build and validate the generalized neophobia scale and establish its prevalence and sociodemographic profile of the participants. Method: an instrumental and correlational study was carried out by applying the generalized neophobia scale to 517 people. Results: the scale has a reliability level that ranges between .79 and .88, the exploratory factor analysis reports a single factor that explains 69.29% of the total variance and the confirmatory factor analysis reports a perfect fit model; the prevalence in the surveyed population was 13.5% and it is women and younger people who report a higher level of neophobia. Conclusions: the theoretical-conceptual contributions of this research can be assessed as consistent and its empirical contribution can be considered as indicative since its main limitation is the selection of the sample determined by accessibility and availability.
Asociación entre estrés agudo y mal control glicémico en adultos mayores más de 60 años con Diabetes Mellitus Tipo 2 atendidos en el Centro Materno Infantil César López Silva mayo a octubre 2021
Authors:   , Cayetano Guizado Karen Lisseth
Published: November 2022

Objetivos “del estudio: Determinar la asociación entre estrés agudo y mal control glicémico en adultos mayores más de 60 años” con “Diabetes Mellitus tipo 2 atendidos en el Centro Materno Infantil César López Silva Mayo a” Octubre 2021. Metodología: Será “un estudio de diseño transversal analítico y” prospectivo. La población estará “conformada por adultos mayores más de 60 años de edad con Diabetes Mellitus tipo 2 atendidos en el Centro Materno Infantil César López Silva durante el año” 2021. Las variables a estudiar serán dos: variable “dependiente, mal control glicémico que será evaluada con el dosaje de hemoglobina glicosilada, donde un valor ≥ 8 %, se” considerará “mal control y variable independiente, estrés agudo que será valorado con la escala PSS-14 que evalúa el nivel de estrés percibido durante el último” mes.
Birds of The Shumagin Islands, Alaska
Authors: Day Robert H. , Byrd G. Vernon , Bailey Edgar P.
Published: November 2022

We studied birds in the Shumagin Islands in 18 of the 37 years from 1970 to 2006 and synthesized all available information on birds of this area. A total of 126 forms of 125 species, including hypothetical species, has been recorded in the Shumagins, of which aquatic birds constitute 67% and terrestrial birds 33%. Overall, 52% of all forms breed, probably breed, or formerly bred; of these, aquatic birds represent 57% and terrestrial birds 43%. The avifauna is heavily weighted toward Nearctic (39% of all forms) and Beringian (32%) forms, followed by Holarctic (21%), Palearctic (6%), and Oceanian (2%) forms; breeding taxa are even more heavily weighted toward Beringian (46%) and Nearctic (40%) forms. The Shumagins have few breeding waterfowl, other freshwater birds, and shorebirds and are not on important flyways for any of these groups, despite lying near important spring and fall staging areas on the nearby Alaska Peninsula. The seabird and terrestrial avifaunas are diverse and similar to those in nearby areas, especially the eastern Aleutians. Populations of several seabird species in the Shumagins have declined substantially over the last 40 years. Two terrestrial species, the Pacific Wren (Troglodytes pacificus) and Pine Grosbeak (Pinicola enucleator), have expanded their breeding ranges into this area, and breeding distributions of some terrestrial birds in the outer Shumagins appear to be changing. Changes in range or breeding status have been caused, at least in part, by predation by introduced foxes, overgrazing by introduced cattle degrading already limited habitat, and the introduction of ground squirrels.
Optimization of Cellulose Nanocrystals from Ensete Ventricosum Pseudo Stem Fiber Using Response Surface Methodology
Authors: Dube Abnet Mengesha
Published: November 2022

In the current world, cellulose is employed in many different applications to create cutting-edge materials like cellulose nanocrystals, which have numerous favorable uses in food packaging, medicine delivery, electronics, and many other fields. In this study, fibers from the Ensete ventricosum pseudo stem were hydrolyzed with sulfuric acid to produce cellulose nanocrystals. To get rid of non-cellulosic and amorphous components, mechanical and chemical pretreatments like water soaking, dewaxing, alkali treatment, and bleaching were carried out. The yield as responses was used to optimize the operation conditions of cellulose nanocrystals extraction from Ensete ventricosum pseudo stem fiber using Response Surface Methodology. The maximum production of cellulose nanocrystals is 39.49 percent with a crystallinity index of 69.7 percent under optimal hydrolysis conditions of 49 percent sulfuric acid concentration, 52°C hydrolysis temperature, and 36 minutes of hydrolysis time. The correctness of the results and the optimization technique itself have both been validated. Consequently, CNCs from EVPSF have potential use in a variety of fields with added value.
Diurnal variation in declarative memory and the involvement of SCOP in cognitive functions in nonhuman primates
Authors: Shimizu Kimiko , Inoue Ken-ichi , Oishi Takao , Takada Masahiko , Fukada Yoshitaka , Imai Hiroo
Published: November 2022

Cognitive functions depend on the time of day in various organisms. Previously, we found that 24-hour recognition memory performance of nocturnal mice changes diurnally through SCOP protein-dependent regulation. It remains unknown whether SCOP-dependent regulation of memory performance is conserved across species with diurnal/nocturnal habits. We tested whether the time of day affects the memory performance of diurnal Japanese macaques. The memory association between bitter taste of drinking water and the nozzle color of the water bottle was established during the light period of the day to evaluate of memory performance for macaques. Here we found diurnal variation of declarative memory in Japanese macaques. The middle of the daytime is the most effective time for memory performance during the light period. To assess whether SCOP is involved in declarative memory performance, we interfered with SCOP expression by using lentiviral vector expressing shRNA against Scop. Scop knockdown in the hippocampus abrogated the memory performance in the middle of the daytime. Our results implicate that SCOP in the hippocampus is necessary for the diurnal rhythm of the memory system and that the SCOP-dependent memory regulation system could be conserved in mammals.
Characteristics of Kenyan Women Enrolled in a Randomized Trial on Doxycycline Postexposure Prophylaxis for Sexually Transmitted Infection Prevention
Authors: Oware Kevin , Adiema Lydia , Rono Bernard , Violette Lauren R. , McClelland R. Scott , Donnell Deborah , Scoville Caitlin W. , Odoyo Josephine , Baeten Jared M. , Bukusi Elizabeth , Stewart Jenell
Published: November 2022

Introduction
The global incidence of sexually transmitted infections (STIs) has been rapidly increasing over the past decade, with more than one million curable STIs being acquired daily. Young women in sub-Saharan Africa have a high prevalence and incidence of both curable STIs and HIV. The use of doxycycline as a prophylaxis to prevent STI infections is promising; however, clinical trials, to date, have only been conducted among men who have sex with men (MSM) in high-income settings. We describe the characteristics of participants enrolled in the first trial to determine the efficacy of doxycycline post-exposure prophylaxis (PEP) to reduce STI incidence among women.
Methods
This is an open-label 1:1 randomized clinical trial of doxycycline PEP efficacy to reduce incident bacterial STIs – Neisseria gonorrhoeae, Chlamydia trachomatis, and Treponema pallidum – among Kenyan women aged ≥18 and ≤30 years. All were also taking HIV pre-exposure prophylaxis (PrEP). We describe the baseline characteristics of participants.
Results
Between February 2020 and November 2021, 449 women were enrolled. The median age was 24 years (IQR 21–27), the majority were never married (66.1%), 370 women (82.4%) reported having a primary sex partner, and 33% had sex with new partners in the 3 months prior to enrolment. Two-thirds (67.5%, 268 women) did not use condoms, 36.7% reported transactional sex, and 43.2% suspected their male partners of having sex with other women. Slightly less than half (45.9%, 206 women) were recently concerned about being exposed to an STI. The prevalence of STIs was 17.9%, with C. trachomatis accounting for the majority of infections.
Conclusion
Young cisgender women using HIV PrEP in Kenya and enrolled in a trial of doxycycline postexposure prophylaxis had a high prevalence of curable STIs and represent a target population for an STI prevention intervention.
A multi factor combination optimization design of a two degree of freedom mechanical system
Authors: Wang Yang , Xu Cheng , He Long
Published: November 2022

Floating machine gun is a typical two degree of freedom mechanical system, and its multi factor combination optimization design is an urgent problem in engineering. In this paper, a two degree of freedom dynamic simulation model of a new floating machine gun with bidirection buffer floating springs is established, and the correctness of the model is verified by comparison with the experimental results. "Maximum recoil displacement of floating body" and “firing speed” is proposed to characterize performance of floating machine gun. The multi factor combination design of floating machine gun is carried out through orthogonal optimization design. The influence of multi factors on the maximum recoil displacement of floating body and firing speed is studied, and the optimal combination solution is obtained. The results show that the pressure of the piston chamber, the energy storage of the floating spring and the mass of the floating body have a great influence on the maximum recoil displacement of the floating body, and the energy storage of the recoil spring and the mass of the bolt carrier group have a great influence on the firing speed. After selecting the best combination according to the variance results, the maximum recoil displacement of the floating body is reduced by about 20.2%, and the firing speed is increased by about 26.6%, which effectively improves the floating performance of the floating machine gun. Keywords: Two degree of freedom system; Floating technology; Machine gun system; Multi factor combination optimization design
Identification and Validation of m6A-GPI Signatures as a Novel prognostic Model for Colorectal Cancer
Authors: Ma Bin , Bao Simeng , Li Yongmin
Published: November 2022

In order to develop an N6-methyladenosine-related gene prognostic index (m6A-GPI) that can predict the prognosis in colorectal cancer (CRC), we obtained m6A-related differentially expressed genes (DEGs) based on The Cancer Genome Atlas (TCGA) and m6Avar database, seven genes were screened by weighted gene co-expression network analysis (WGCNA) and least absolute shrinkage and selection operator (LASSO) analysis. Then, m6A-GPI was constructed based on the risk score. Survival analysis indicated that patients in the lower m6A-GPI group have more prolonged disease-free survival (DFS), and different clinical characteristic groups (tumor site and stage) also showed differential risk scores. In the analysis of the molecular characteristics, the risk score is positively associated with homologous recombination defects (HRD), copy number alterations (CNA), and the mRNA expression-based stemness index (mRNAsi). In addition, m6A-GPI also plays an essential role in tumor immune cell infiltration. The immune cell infiltration in the low m6A-GPI group is significantly higher in CRC. Moreover, we found that CIITA, one of the genes in m6A-GPI was up-regulated in CRC tissues based on real-time RT-PCR and Western blot. m6A-GPI is a promising prognostic biomarker that can be used to distinguish the prognosis of CRC patients in CRC.
The influence of cathodic θ-Al2Cu intermetallic geometry on the localized-corrosion-triggered conversion coating deposition
Authors: Sainis Salil , Zanella Caterina
Published: November 2022

Micro-galvanic activity between the cathodic intermetallics and the anodic matrix in an aluminium alloy drives the localized deposition of cerium conversion coatings. It is at the cathodic sites that conversion coating deposition is initiated due to the local pH gradient created because of cathodic reduction reaction over them. The intermetallics’ chemical, electrochemical and geometrical properties critically influence the deposition, but very little is empirically known about the latter. With the objective of understanding the effect of intermetallic geometry, this work looks closely into the deposition on nearly 550 eutectic θ-Al2Cu type intermetallics with different size regimes to decipher the controlling geometrical variables. While this work investigates influence of intermetallic geometry on localized deposition, parallel conclusions may also be drawn about the corrosion activity around intermetallics as a function of their geometry due to these coatings being triggered by localized corrosion.
Nurses lived Experiences, burdens and coping strategies during the COVID-19 pandemic
Authors: Jarrad Reem , ALdasoqi Khadeejeh , ALnatsheh Malak
Published: November 2022

This is a qualitative interpretative phenomenological study which was designed to navigate through nurses’ lived experiences, burdens and both positive and negative coping strategies while working with COVID-19 patients. The sample included 20 nurses who had worked with COVID-19 patients for more than or equal to six months in the country’s variable health sectors. The interviews were conducted between 1,October,2021 and 15,April,2022. At that time, the third COVID wave had elapsed and we were peaking on a fourth pandemic wave, so included participants had lived through a minimum of two to three peaks. Six themes had emerged which were: nurses coping with COVID-19 crisis, professional relationship burden, personal burden, environmental burden, physical symptom burden and emotional burden of the crisis. Nurses lived experiences during the pandemic were deep and intense and moderately to highly affecting their ways of thinking, feeling and behaving. Certainly such experience had opened nurses eyes on countless number of challenges that could be faced during the times of adversity which requires special attention, care and preparation on many levels. The minimal preparatory levels are personal, departmental, organizational and strategic at the level of country’s proactive health planning.
Recurrent Headaches After Spinal Anesthesia and Their Link to Associated Factors of Candidates for Cesarean
Authors: Abdi Kamel , Abdullahzadeh Mehrdad , Gholamveisi Behzad , Aghabakpour Hatam , Karimian Aram
Published: November 2022

Background Spinal anesthesia (SA) is widely administered in cesarean sections (CS), and post-dural puncture headache (PDPH) is the most unavoidable complication after the Dural or lumbar puncture (LP). Some factors are considered to be associated with the risk of recurrent PDPH.
Aims To investigate the recurrent headaches after SA and their link to associated factors of age, Body Mass Index (BMI), Fast Blood Sugar (FBS), Blood Pressure (BP), time of immobilization in the supine position after SA, and a history of previous SA of PDPH of women candidates for CS, when the needle type and size were kept constant.
Methods In a cross-sectional descriptive study, 80 women candidates for CS were recruited from Besat Hospital, Sanandaj, Iran. The association between age, BMI, FBS, BP, time of immobilization in the supine position after spinal anesthesia, and a history of previous SA and recurrent PDPH of women candidates for CS were investigated using statistical t-tests and chi-square test.
Results The t-test and chi-square test showed no association between the quantitative and qualitative variables and PDPH after SA in women candidates for CS respectively.
Conclusion The results of this study showed when the needle type and size were kept constant, the associated factors of age, BMI, FBS, BP, time of immobilization in the supine position after SA, and a history of previous SA and PDPH of women candidates for CS had no link to the recurrent headaches after SA.