bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and genetic diagnosis of two Turkish patients with hereditary spherocytosis
Authors: Coşkun Çağrı
Published: August 2024

Hereditary spherocytosis is a congenital disorder caused by defects in the erythrocyte membrane. It is characterized by hemolytic anemia, jaundice, splenomegaly, and cholelithiasis. The clinical presentation is variable. Especially in the neonatal period and cases without a family history, it isn't easy to diagnose with classical approaches. Here, we describe the genetic findings of a 1.5-month-old and a 2-month-old girl diagnosed with hereditary spherocytosis in Turkish families. Both cases presented with severe anemia and jaundice. Spherocytes were frequently seen in peripheral blood smears. Targeted next-generation sequencing (NGS) revealed that the 1.5-month-old girl was heterozygous for a novel frameshift mutation c.1617del (p.Leu540CysfsTer31) in exon 15 of the ANK1 gene, while the 2-month-old girl was heterozygous for a mutation c.1912C>T (p.Arg638Ter) in exon 13 of the SPTB gene, which leads to abnormal protein truncation. Parents did not carry these mutations. To our knowledge, the ANK1 mutation identified in a 7-month-old girl has not been reported previously. NGS may be helpful in diagnosing hereditary spherocytosis, especially in atypical cases.
Na granicy. Profesor Ewa Nowina-Sroczyńska jako Mistrzyni
Authors: Ludwiczak Kamil , Raj Monika
Published: August 2024

Nauczyciel nie musi, ale może być mistrzem. Wtedy ma on wielki wpływ na twórczość swojego ucznia. Między innymi o tym jest nasz tekst. Profesorka Bożena Ewa Nowina-Sroczyńska była i jest, bez wątpienia, mistrzynią dla wielu osób, których biografie zrosły się z łódzką etnografią, etnologią i antropologią kulturową. W niniejszym artykule szkicujemy portret Jubilatki przez pryzmat prac dyplomowych, których była promotorką i opiekunką na przestrzeni ponad trzech dekad. Analizujemy ich tytuły, identyfikując ścieżki transmisji „antropologicznej szkoły Ewy Nowina-Sroczyńskiej”. Prezentujemy wspomnienia na Jej temat, którymi podzieliły się z nami osoby studiujące etnologię i antropologię kulturową w Łodzi, które miały okazję – jako ostatnie – spotkać się z Nią na zajęciach. W roku akademickim 2021/2022 Profesorka Ewa Nowina-Sroczyńska miała ostatnie w swojej karierze zajęcia, co tłumaczy pierwszy człon tytułu naszego tekstu – na granicy.
Exploring Polybag Size, Nursery Mixtures and Rootstocks for Optimizing Lasoda (Cordia myxa L.) Nursery Techniques
Authors: Meghwal P.R. , . Sourabh , Singh Dalpat
Published: August 2024

Background: Lasoda (Cordia myxa L.) is lesser utilized fruit plant species suitable for growing in large parts of arid and semi-arid regions of India. Besides the economic importance of its fruits in the vegetable and pickle industry, this species is also known for ethnomedicinal properties in different plant parts. In order to utilize it to its fullest potential, standardization of nursery technology for mass multiplication by vegetative propagation method is a necessary step. With the above background in the view, an experiment was conducted to see the effect of polybag size, nursery mixture and rootstock on seed germination, growth of seedlings after germination, budding success and growth of budded plants. Methods: The study was conducted during June-September, 2020. The treatment comprised of two polybag sizes, six nursery media compositions and two kinds of rootstocks. The observations were recorded on seed germination, seedling growth, days to bud sprout after budding, budding success and shoot length and diameter after 30 days of budding. Result: The main effects of nursery mixture revealed that plant height, stem diameter, number of leaves, shoot length and shoot diameter after budding were significantly affected by nursery mixture composition. The highest plant height (29.53 cm) recorded in the M4 mixture was significantly higher over M1, M2 and M3 but the differences were non-significant when compared with M5 and M6. A similar trend was also recorded in the case of stem diameter and number of leaves which showed significantly higher values in M4, M5 and M6 as compared to M1, M2 and M3. The highest shoot length (8.34 cm) and shoot diameter (3.40 mm) were recorded in M5 and M4 which were significantly higher than most of other media levels.
Arabic Language Module For Madrasah Ibtidaiyah
Authors: Sanjaya Budi , Hidayat Wahyu
Published: August 2024

This study aims to analyze the effectiveness of using Arabic language modules developed for students of Madrasah Ibtidaiyah.  The material represented essential learning and was relevant to everyday life. This study uses Design and Development Research (DDR) with the ADDIE model. The effectiveness testing stage was carried out at MIS of Nurul Ijtihad Lubuk Gaung, Indonesia, involving ten third-grade student participants. Qualitative data comes from the validation of media, material, language, and teacher practitioner experts. Meanwhile, quantitative data is obtained from test results. Data were analyzed qualitatively, and quantitative data were analyzed using paired t-test analysis. The study results showed that this Arabic language module was feasible and well-used for teaching Arabic in elementary schools. It also shows the development of significant student learning outcomes using this module.
A Qualitative Exploration Of The Impact Of Fostering AFL Learners' Vocabulary Skills Using BBC Arabic Live News
Authors: Sathikulameen A , Ahamedullah M , Ali Ibrahim A.M. , Ansari Thameem , Vijayakumar S
Published: August 2024

This qualitative study aims to analyze the impact of BBC Arabic Live on fostering vocabulary skills. The subject totaled 37 slow learners in their bachelor of art program; the Arabic department was at The New College, Chennai, India. The Experimental Group was trained for vocabulary acquisition through ten classroom activities using BBC Arabic Live. The qualitative questionnaires were given after carrying out the classroom activities. The data were analyzed using a qualitative approach. The results showed that a live BBC Arabic News classroom activity approach brought about potential changes in their vocabulary acquisition. This study applied pedagogical implications for fostering vocabulary skills through listening skills. It underscored the practical importance of student-centered approaches for honing modern Arabic vocabulary skills. Overall, the study's findings point to the potential benefits of using BBC Arabic Live in the classroom to help students learning Arabic as a foreign language acquire vocabulary. The study's findings emphasize the necessity of learner-centric and student-centered approaches to language learning, which has significant ramifications for approaches to language teaching in higher education. Future studies in this field might look at the impact of vocabulary development on other language abilities like reading and writing, or they might examine the usage of different media sources for vocabulary acquisition.
Multilingual Education in Islamic Boarding Schools: Planning, Implementation and Institutional Policy/ Pendidikan Multi Bahasa Di Pesantren: Perencanaan, Implementasi Dan Kebijakan Kelembagaan
Authors: Nasir Amin , Juhri Juhri , Karim Abdul
Published: August 2024

This study investigates cases of language 'policing' as educational language policies and how these are represented across different policy levels. Focusing on Indonesian schools and using discursive approaches to language policy as a theoretical framework, I critically examine institutions' motivations and justifications for designing and implementing policies whereby non-standardized forms are 'banned' and how these are reported in metalinguistic discourse. Drawing on a range of data, including media discourse, policy documents, teacher interviews, and linguistic landscapes, I textually trace how educational language policies (re)produce prescriptive and linguist ideologies, often using metaphors of crime and often using language as a proxy for social factors such as academic achievement, employability, and standards. Overall, micro- and meso-level language policies are a partial product of linguistic conservatism in current macro-level educational policy. (Language policy, language policing, schools, language ideologies).
Validating Curriculum-Based Measurement Oral Reading Fluency (CBM ORF) Applicability To Evaluate Arabic Readers’ Performance
Authors: Alqahtani Saeed Saad
Published: August 2024

While curriculum-based measurement (CBM) accurately indicates reading skills, such as progress monitoring and early detection of reading difficulty, it has yet to be developed for Arabic. This study aimed to develop and validate a curriculum-based measurement for oral reading fluency (CBM-ORF) tailored to assess Arabic language students' reading abilities and create preliminary norms for students from second to sixth grades. Methods and Procedures: Various forms of the CBM-ORF were developed and administered to a sample of 414 students. After data analysis, the students' readings were rated by teachers to compare the CBM-ORF with an independent measure. Outcomes and Results: The results indicate that the CBM-ORF exhibits strong reliability and validity, making it a valuable tool for monitoring progress and identifying reading difficulties in Arabic readers. Furthermore, ORF norms have been established and proposed. Conclusions and Implications: This study emphasizes the absence of a valid reading tool for Arabic language students. It offers resources for teachers to make data-driven decisions, especially for students with learning disabilities.
Lo que puede una fotografía
Authors: Gamarnik Cora
Published: August 2024

El artículo aborda el caso de una fotografía de prensa que tuvo un impacto determinante sobre el poder político, judicial y económico de Paraguay y posibilitó la interrupción de la contaminación de una laguna. Analiza bajo qué circunstancias y a través de qué actores fue posible este hecho excepcional, así como los motivos por los cuales una fotografía de prensa pudo tener tanta eficacia. En este sentido, se analiza lo que muestra la fotografía, sus condiciones de producción y circulación, los efectos que generó su publicación, pero también tiene en cuenta las reacciones políticas, sociales y mediáticas que ocurrieron en torno a una imagen que terminó siendo un eslabón clave para denunciar la contaminación. Asimismo, reflexiona sobre el poder de la fotografía para promover cambios sociales y su potencial para denunciar problemas ecológicos con impactos visibles. El análisis cruza estudios de fotografía de prensa, medios de comunicación, redes sociales, el papel de los influencers y las luchas ecológicas, e invita a seguir pensando el poder de este tipo de imágenes.
Entrevista a Mario Carlón
Authors: Bañuelos Capistrán Jacob , Rigat Leticia
Published: August 2024

Mario Carlón es una figura destacada en el campo de los estudios sobre mediatización y circulación del sentido. Sus investigaciones han aportado una perspectiva innovadora y profunda sobre las transformaciones que ha experimentado la sociedad contemporánea, especialmente en relación con la emergencia de las redes sociales mediáticas y los nuevos actores/enunciadores que han surgido gracias a ellas. La relevancia de su trabajo radica en su capacidad para analizar y conceptualizar estos fenómenos desde un enfoque multidisciplinario, que combina la semiótica, la comunicación y la teoría social.
Cultivar Differentiation and Quality Changes Monitoring of Strawberry during Storage using Electronic Nose
Authors: Kim Ji-Young
Published: August 2024

Strawberry, Fragaria x ananassa Duchesne, is a popular fruit with unique aromas and a sour-to-sweet taste. Aroma is an important aspect of identifying the quality of Strawberry during storage after harvesting. In this study, an electronic nose was used to identify the characteristics of volatile organic compounds produced in the Strawberry during storage and compare differences in characteristics of volatile organic compounds according to the cultivar of Strawberry. The results indicate no difference between quality indexes in Strawberry except for the weight loss (WL) and volatile organic compounds (VOCs) production during storage. The WL of Seolhyang (ST1) and Geumsil (ST2) increased from 0 to 10 d. VOCs in ST1 correlated to 1-Propanol, 2-methyl-, methyl hexanoate, propyl nonanoate, methyl formate, (Z)-3-Hexen-1-ol, and (E)-2-hexenal during the storage period at 5 ℃. VOCs in ST2 were identified as 5-ethyl-3-hydroxy-4-methyl-2(5H)-furanone, 2-ethyl-3-methylpyrazine, methyl butanoate, (Z)-3-Hexen-1-ol, and methyl hexanoate. These VOCs can be used as biomarkers in the early detection of undesirable flavor production in the food industry and crucial factors in the shelf-life determination of Strawberry during storage.
Regulation of Gene Expression by Thyroglobulin
Authors: Kiriya Mitsuo
Published: August 2024

Thyroglobulin (Tg) is a large glycoprotein consisting of 2,768 amino acid residues and the precursor of thyroid hormones (THs). Since abnormalities in Tg function and expression may naturally affect thyroid function, there has been much interest in the mechanisms that regulate the expression and maturation of Tg. By contrast, Tg found in the blood, because of leakage from thyroid follicles, is used as a marker of thyroid goiters and inflammation. However, the precise structure and function of the huge Tg macromolecule are still unclear. Recently, it was shown that Tg at its physiological concentration in follicles dynamically regulates the expression of various thyroid-specific genes responsible for counteracting the effect of TSH. In addition, it was also shown that Tg induces thyroid cell proliferation. Thus, follicular Tg is now recognized as an autocrine negative-feedback regulator tightly controlling follicular function. In this review, we will briefly summarize recent advances of Tg function. Keywords: Thyroid; Thyroglobulin; Thyroid hormones; TSH
Impact of Serum Progesterone Levels on Pregnancy Outcomes in Patients Undergoing Artificial Endometrial Preparation for Embryo Transfer
Authors: Tarasconi Diego
Published: August 2024

In this retrospective cohort study, we examined the impact of measuring serum progesterone (P) levels on pregnancy outcomes in patients undergoing artificial endometrial preparation and embryo transfer (ET). We analyzed 342 ET cycles at the blastocyst stage, either from autologous or donated oocytes, in a private fertility care center. ET cycles were performed after an artificial endometrial preparation with a sequential administration of estradiol valerate followed by vaginal micronized progesterone. In the study population, when serum P levels were lower than 10.0 ng/ml the day prior to ET, a subcutaneous preparation of P was added, attempting to bring its levels to the luteal phase support. Interestingly, in the case of autologous ET, the rates of early pregnancy loss were reduced by measuring and eventually supplementing serum P levels. Keywords: Serum progesterone; Blastocyst transfer; Early pregnancy loss; Frozen embryo transfer; Endometrial preparation Abbreviations: P: Progesterone; ET: Embryo transfer; IVF: In vitro fertilization; HRT: Hormone replacement therapy; OPU: Oocyte pick-up; ICSI: Intracytoplasmatic sperm injection
On the Subject of Treatment of Disseminated Autonomies of the Thyroid Gland
Authors: Manfred Doepp
Published: August 2024

Disseminated autonomies represent a problem within the therapy of thyroid dysfunctions. They no longer submit to TSH control. They are difficult to operate on but require definitive treatment as they can lead to manifest hyperthyroidism. Fractionated low-dose radioiodine treatment is presented as a solution in this case. Because the effective dose is readily adjustable, late hypothyroidism can be avoided.
The Impact of Thyroid Function on Human Reproduction: A Comprehensive Mini-Review
Authors: Bulletti Francesco Maria
Published: August 2024

Thyroid disorders are common endocrine disorders affecting millions of individuals worldwide. The thyroid gland plays a crucial role in regulating various physiological processes, including reproductive health. This scientific article aims to provide a comprehensive review of the current understanding of the impact of thyroid function on human reproduction. We discuss the physiological role of thyroid hormones, the effects of thyroid dysfunction on fertility, pregnancy outcomes, and the management of thyroid disorders in the context of reproductive health. The effect of hypothyroidism on human embryo’s implantation as well as the replacement therapy efficacy in reversal detrimental effects are discussed. Keywords: Thyroid; Thyroid dysfunction; Human reproduction; Fertility; Pregnancy outcomes; Thyroid hormones; Hypothalamic-pituitary-thyroid axis; Reproductive health; Preconception care; Pregnancy management; Embryo’s implantation
Conflict dynamics, political-economy, and natural resources in the Bangsamoro Autonomous Region
Authors: Herbert Siân
Published: August 2024

The rapid evidence review on the Bangsamoro Autonomous Region in Muslim Mindanao (BARMM) highlights significant socio-economic factors driving conflict, including poverty, land disputes, and resource competition. Despite economic progress since the peace agreement, BARMM remains one of the poorest regions in the Philippines. Land issues, such as clan rivalries and unresolved ownership, exacerbate conflicts. Mineral resources like gold and nickel are underexploited due to historic conflicts, corruption, and environmental concerns. Governance challenges and delayed peace process implementation further complicate stability and development.
In Silico Analysis of Active Compounds from Allium tuberosum as Drug Candidate for Inhibitor DENV-3 Envelope Protein
Authors: Nuryady Moh Mirza , Juliana Levina Imelda , Ariesaka Kiky Martha
Published: August 2024

Dengue fever has become a global health issue, the development of dengue vaccine has not yet been established. Medicinal plants are an ideal alternative for DENV infection drugs. The purpose of this study was to determine in silico the potential of active compounds from Allium tuberosum as envelope protein inhibitors of DENV-3. The method of this research is to do docking analysis of compounds with DENV-3 envelope protein and analysis of amino acid residues using MVD, pharmacokinetic analysis using SwissADME, toxicity analysis using ProTox-II. The best docking value for the potential activity to inhibit the receptor DENV-3 is the thymidine compound (RS: -81.1245 kcal/mol). The highest activity of thymidine is the most promising as a drug candidate, as evidenced by the toxicity analysis which is predicted to have non-carcinogenic, non-mutagenic, inactive properties against hepatotoxicity, cytotoxicity and immunotoxicity parameters, as well as pharmacokinetic analysis that fulfills 6 parameters of lipopolicity, molecular weight, polarity. , insolubility, insaturation, and flexibility which indicate the drug candidate of thymidine is safe for its bioavailability. The conclusion from the results of this study is that one compound has the ability as an antiviral, binding score with DENV-3 is good, and is safe in terms of pharmacokinetics and toxicity, namely thymidine compound.
Antibacterial Activity of Plumeria alba L. Leaf Ethanol Extract Against Propionibacterium acnes
Authors: Komala Oom , Srinarayani Kadek , Utami Novi Fajar
Published: August 2024

The Plumeria alba L. leaves are empirical as an alternative to treatment as an antibacterial to Propionibacterium acnes, Staphylococcus aureus and Salmonella typhi, as aromatherapy for the repellant and the denture cleanser of the growth of the Candida albicans in the synthetic nylon base. It has been known to contain alkaloids, flavonoids, saponin, tannin, and fenol that have activity as antibacterial. The study aims to determine the antibacterial activity and to identify the best concentration of 70% ethanol extract of P. alba L. leaf to P. acnes. The method used in extraction is a maceration with 70% ethanol solvent which is concentrated using a rotary evaporator. Extract of ethanol 70% of P. alba L. leaves was used to determine antibacterial activity by determining the Minimum Inhibitory Concentration (MIC) using solid dilution and the width of inhibition area by diffusion method of paper discs at concentrations of 30%, 40%, and 50%. Phytochemical tests were carried out of alkaloid, flavonoid, saponin, tannin and fenol qualitatively. The result showed that ethanol 70% extract of P. alba L. leaf had antibacterial activity against P. acnes with MIC at 25% concentration. The best antibacterial activity from ethanol extract 70% of P. alba L. leaves at a concentration of 50% with inhibitory, namely 9.4 mm. The P. alba L. leaves phytochemical test contains alkaloids, flavonoids, saponins, tannins, and fenol. The conclusion ethanol extract 70% of P. alba L. leaves have the antibacterial activity against P. acnes.
Identification of Rossby Atmosphere-Tropical Cyclone in Eastern Indonesian Waters
Authors: Suhendar Maldiva Hafiza Anjarika , Yulihastin Erma , Syalsabilla Alya Fitri , Azzahra Syifa Alifia , Handoyo Gentur , Ridwan Agus Wawan , Dawami Maulana Dwi Nur
Published: August 2024

Recent research has revealed that tropical cyclones can develop over eastern Indonesian waters influenced by marine heatwaves and Rossby waves in the atmosphere. However, there is no study documenting tropical cyclones that occur in conjunction with atmospheric Rossby waves (Rossby Atmospheric-Tropical Cyclones) and their association with increased sea surface temperatures in eastern Indonesian waters. This study aims to document the influence of Rossby waves in the atmosphere on the formation of tropical cyclones around the Indonesian region using 5 case studies in 2017-2022, namely: December 2017, January 2020, December 2020, December 2021, and April 2022. This study uses wind data, sea surface temperature, specific humidity, and temperature (2m) obtained from the European Re-Analysis (ERA5) with a temporal and spatial resolution of one hour and 0.25°×0.25°. The identification of Rossby waves is based on the Rossby index issued by the North Carolina Institute for Climate Studies (NCICS). In this study, the Rossby Atmosphere-Tropical Cyclone is grouped into three phases, namely: early phase, mature phase, and late phase, using composite and statistical methods to calculate anomalies. The results showed that in the early phase, the existence of Rossby waves was shown by two twin vortices over eastern Indonesia, which was supported by high specific humidity, warming sea surface temperature (>+0.4°C), and higher surface temperature (>+0.3°C) over Timor. In the mature phase, the twin vortices over eastern waters transformed into a tropical cyclone over the Philippines. In the final phase, specific humidity decreases, sea surface temperature cools (<-0.3°C), and surface temperature decreases (<-0.3°C). The results also prove the crucial role of Timor waters in forming Rossby waves that can grow into tropical cyclones around Indonesia.
Spontaneous intracranial hypotension in young and middle-aged patients with chronic subdual hematoma in Korea: three case reports
Authors: Lee Ae Ryoung , Choi Yun Suk
Published: August 2024

This case series highlights chronic subdural hematoma in previously healthy young and middle-aged patients, where symptoms persisted despite initial surgical intervention. Subsequent diagnosis revealed spontaneous intracranial hypotension through computed tomography myelography. All patients experienced symptom relief after undergoing epidural blood patch. In conclusion, spontaneous intracranial hypotension should be considered in chronic subdural hematoma cases without trauma or underlying disease, with epidural blood patch recommended before surgical intervention if spontaneous intracranial hypotension is suspected.
Study of Environmental Parameters on Lobster (Panulirus spp.) Enlargement with Fixed Cage at GWD, Banyuwangi
Authors: Putra Riswanda Rangga , Nugraha Dimas Putra Wahyu , Albarkah M. Rafly , Ma’arif M. Chusnan , Fatih M. Fachrul , Hadi Moch. Irfan , Violando Wiga Alif , Nusa Raras Widya
Published: August 2024

One of the marine commodities, Lobster (Panulirus spp.), has unabated demand in the global market, while, Lobster production remains static due to the difficulty of implementing its rearing activities. Relative rearing of lobster (Panulirus spp.) is usually performed using the floating net cage method with calm water conditions. In contrast, areas with extreme weather conditions tend to have difficulty applying this method. The potential of using the fixed cage method was assessed by rearing the Lobster at Pesona Bahari Banyuwangi Fish Cultivation Group. This research aimed to investigate the feasibility of the environmental conditions in the waters of GWD, Banyuwangi. The study was conducted for three months. Data such as temperature and light intensity through the help of a pendant was collected. Water quality parameters were recorded during this study, including salinity, pH, dissolved oxygen, and current velocity. Sampling was conducted four times to see the relationship between length and weight. The results showed that the GWD environmental parameters were very supportive for lobster rearing, with temperature values ​​ranging from 27.2oC - 30.1oC, DO around 4.6 mg/l - 5.2 mg/l, salinity 28o/oo - 30o/oo, pH 7 - 8.2, the current speed is 0.468 m/s, and the light intensity is 0 lux - 3,616 lux. The growth pattern of all sampling results except sampling 2 (isometric) has a negative allometric result, with length and weight having a solid relationship. The fixed cage method is considered suitable for lobster rearing activities because the environmental parameters follow their natural habitat and the Fulton condition factor (K) value of more than 1. The greater the value of the Fulton condition factor (K), the healthier the condition lobster.
Antibacterial Potention and pH Analysis of Kombucha with Anna Apple (Malus domestica) Peel as Its Substrate
Authors: Lestari Kinanti Ayu Puji , Wulansari Silvi Ayu
Published: August 2024

This study aimed to determine the antibacterial abilities of Kombucha with Anna apple peel as the substrate. This study was conducted on the antibacterial assay of Kombucha with the formulation of 10g (formulation A), 15g (formulation B), and 20g (formulation C) apple peels. Each formulation then made three different test concentrations of an antibacterial test by the Kirby Bauer method. There was a decrease in the pH value measured before and after fermentation of kombucha apple peel due to the production of acetic acid formed from metabolic activity between bacteria and yeast as a culture of kombucha beverage. The results of the antibacterial test showed that all of the test concentrations could inhibit the growth of the test bacteria until they were in the category of medium and high inhibition. The largest diameter of the inhibition zone was shown by formula C with a concentration of 100% (17 mm). The diameter of the inhibition zone is directly proportional to the amount of apple peel contained in the formula and the concentration of the sample being tested.
Making Liquid Sugar Preparations from Lombok-Traditional Sugarcane Juice and Its Potential as Anti-Diabetic Sugar
Authors: Nurul Furqan Baiq Repika , Maharani B Fitria
Published: August 2024

The prevalence of Patients with Diabetes Mellitus remains on the rise worldwide. Diabetes is a multifactorial disorder that emboils genetic and environmental factors such as an unhealthy diet by consuming white sugar crystals. White crystal sugar consists of less chromium content that induces glucose in the blood to the cells, which can trigger hyperglycemia or high blood sugar levels. Chromium works by increasing the activity of insulin receptors to enhance glucose translocation to the cell. Previous studies showed sugarcane Nira had a high level of chromium compared with those processed into white crystalline sugar. However, it could not be used as a sweetener substitute since its storage age was only 2 to 3 days. This study identified that the treatment process of Lombok's Nira sugarcane into local liquefied sugar should be addressed to maintain chromium levels compared to the processing of Nira into the white crystalline sugar requiring optimum sucrose and omitting several minerals. Hence, sugarcane Nira as a refined sugar product can substitute for white sugar consumption in diabetes patients.
Comparison of the Effectiveness of Piper Crocatum and Sour Turmeric Acid for Healing Time
Authors: Lestari Dewi , Usman Andi Nilawati , Alam Gemini , Hadju Veni , Husin Farid , Sartini Sartini
Published: August 2024

Maternal mortality (MMR) is still 359 per 100,000 live births, and the expected target is still far from what was proclaimed in 2030, the number of 70 per 100,000 live births. Based on data from WHO (Word Health Organization), in 2015, the deaths were around 2.7 million cases caused by perineal injuries. According to IDHS data (Indonesian Demographic and Health Survey), in 2017, the maternal mortality rate (MMR) was 305 per 100,000 live births caused by an infection in the perineal wound. The total maternal mortality rate (MMR) in various provinces in Indonesia has decreased from 4,226 to 4,221. In 2019 the maternal mortality rate (MMR) was most contributed by bleeding (30.3%) and postpartum infection (5%). This study aimed to determine the differences in the effectiveness of red betel and turmeric acid in the complementary wound healing treatment in postpartum women. This study was a quasi-experimental pretest-posttest control group design with a total sampling method by giving three intervention and control groups, as many as 30 postpartum women with perineal wounds grades I and II according to the inclusion criteria with the group given red betel, tamarind, and turmeric. Control group at Anutapura General Hospital Palu. Perineal wound care using the REEDA scale (Redness, Edema, Ecchymosis, Discharge, and Approximation). The results showed a difference in the effectiveness of red betel and turmeric acid on perineal healing. The average Mann-Whitney statistical test results were on the 5th and 7th days (P-Value < 0.005). This study shows that Piper crocatum can accelerate perineal wound healing and become an alternative for complementary therapy and perineal wound healing.
Relative Expression of mRNA BARF1 Epstein-Barr Virus from Tumor Tissue Biopsy in Formalin-Fixed Paraffin-Embedded in Nasopharyngeal Carcinoma
Authors: Wahyono Daniel Joko , Fuadi Muflih , Susanto Agus Hery , Sulistyo Hidayat
Published: August 2024

Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from nasopharyngeal epithelial cells. NPC is endemic in some regions, especially in Southeast Asia countries. NPC is also a multifactorial disease involving environmental factors, genetic factors, and infection from Epstein-Barr virus (EBV). According to WHO classification, Undifferentiated NPC is histopathologically associated with EBV infection and categorized into WHO subtype 3. EBV has two phases in its infection cycle: the lytic and latent phases. The BARF1 gene is a mediator of the transition from the latent phase to the lytic phase. Previous studies suggest measurement of EBV mRNA activity at the primary tumor site in the nasopharyngeal reflects the pathogenesis of NPC rather than measuring circulating EBV DNA or serological diagnosis. This study aimed to determine the relative expression potential of BARF1 mRNA at different tumor stages in NPC patients as a predictor of NPC pathogenesis. This research design was a descriptive research method in the form of a cross-sectional study. The samples used were 22 patients diagnosed as NPC WHO class III at the Anatomical Pathology Section of Prof. Dr. Margono Soekarjo, Purwokerto, who met the inclusion criteria. The relative expression of BARF1 mRNA was carried out using the one-step real-time RT-PCR technique and then calculated using a formula of 2-ΔCt. The T-test was used to compare the relative expression of early and late-stage BARF1 mRNA. The relative expression of BARF1 mRNA in the late-stage advanced stage (n = 6; 0.708292-0.840177; med = 0.7164655) was increased compared to the early stage (n = 2; 0.708841-0.712423; med = 0. 710632).
Characterization of Potential Perennials as Erosion Retainers in the Brantas River Border Based on Different Environmental Bases in Malang, East Java
Authors: Bad'a Farohii Subhan Maulidi Kun , Rohman Fatchur , Sulisetijono Sulisetijono
Published: August 2024

Research on the characterization of potential perennials to resist river erosion in the Brantas river border based on different environmental features in Malang, East Java has been carried out. The research aims to know the composition of plant species, plant diversity, and the dominance of perennials that can prevent erosion. The study used vegetation analysis with cruise methods, exploring perennials on the Brantas river border based on different environmental settings (residential industry, environment, fields). The results of the study found 49 species of plants in 25 families, the diversity of hard plants in the residential environment was high with H' 3.06 while in the industrial and rice fields/fields environment it was moderate with H' 2.67 (Industry) and H' 1.90 (fields). The dominant plants are Gigantochloa apus (Schult. f.) Kurz ex Munro (Industry) species, Calliandra houstoniana (Mill.) Standl. (Settlement) and Pinus merkusii Jungh. & Vriese ex Vriese. (fields) Many perennials in the study area can prevent erosion because these plants meet the criteria of a strong root system and economic value.
Keywords: Perennials, Erosion, Border, Brantas River
The Identification of Mushroom Species Variety in Mekar Lestari Local Fruit Park
Authors: Pratama Candra , Rezeki Amalia , Hoesain Ferry F.
Published: August 2024

Mekar Lestari Local Fruit Park is a park managed by the Indonesian Center for Biodiversity Studies and Conservation. This park has a collection of local fruit plants located in Anjir Muara, Barito Kuala Regency. One of the potential organisms found in this area is fungi. The purpose of this study was to identify the types of fungi in the local fruit garden area "Mekar Lestari" using the exploration method with the selected sample technique. The data obtained were then analyzed by descriptive method. Based on the results of research that has been carried out in the forest in the local fruit garden area "Mekar Lestari" found 15 species of fungi namely Arcyria cinerea, Calocera cornea, Daldinia concentrica, Marasmius siccus, Physarum polycephalum, Physarum album, Volvariella sp, Trametes sanguine, Trametes ochracea, Schizophyllum commune, Collybia cookie, Xylaria polymorpha, Scleroderma cepa, Auricularia sp, and Ductifera pululahuana. The types of fungi found in this study are divided into 12 families and 13 genera. The environmental conditions of the study site were temperature 30.2-37.7 °C, air humidity 77.0-84.8%, light intensity 198-2460 lux and soil pH 6.3-7. The fungi found generally live on decaying wood and litter, and a small proportion live attached to trees
"Bau Nyale " from the perspective of Science, Local Wisdom and Ecotourism
Authors: Sucilestari Ramdhani , Ramdani Agus , Susilawati Susilawati , Sukarso AA , Rokhmat Joni
Published: August 2024

Bau Nyale  is an annual tradition of the Sasak people in Central Lombok, which is celebrated every year on the 20th of the 10th month according to the Sasak calendar. This tradition comes from a legend that lives in society about the sacrifice of a princess to maintain the peace and unity of her country. Through a multidisciplinary approach that combines the perspectives of science and ecotourism sustainability, this study aims to present a comprehensive understanding of the Nyale legend and phenomenon and their associated ecotourism implications. This research method includes a literature study, field observations and interviews. The results of this study provide a deeper understanding of the legend of Princess Mandalika, the Bau Nyale  phenomenon, and the related ecotourism implications. It was found that Nyale rituals have significant ecological and social impacts, including potential reductions in Nyale sea worm populations and changes to local culture. Therefore, sustainable ecotourism management is needed to ensure the sustainability of this phenomenon in the long term. This research has important implications in cultural preservation and environmental conservation. It is hoped that this study can contribute to an understanding of the interaction between cultural traditions and ecotourism and become a basis for developing sustainable management strategies in the context of the Bau Nyale  phenomenon.
The Effect of Using E-modules in Biology Learning on Learning Outcomes of High School and University Students: Meta-Analysis
Authors: Arifin Nurfadila , Effendi M. Harja , Purwati Nining
Published: August 2024

This study aims to determine the effect size (ES) of the application of e-modules in biology learning on student's learning outcomes. This study uses the type of meta-analysis research. The research sample consisted of 14 articles sourced from the results of article identification through Google Scholar and Eric. The research data were collected based on the reference of inclusion and exclusion criteria. Data analysis was conducted by calculating the ES value using Cohen’s d formula. The results of data analysis showed that there were 14 articles divided into two levels of education, namely high school (9 articles) and university (5 articles) with a total average effect size score of 1,14 which means the effect size criteria are very large (VL). The ES average score for the high school level is 1,20 or very large (VL) ES average, while the ES average score for the university level is 1,02 or categorized as large (L) ES average. Therefore, it can be concluded that the effect size of the application of e-modules in biology learning has a significant impact on improving student learning outcomes.
Exploring the knowledge and awareness of emulsifiers in food and non-food products among the community in Brunei Darussalam
Authors: Bustani Nurul Izzati , Haji Mustapa Aklimah
Published: August 2024

The demand for halal products in both food and non-food sectors is directly correlated with the growth of the Muslim population. Hence, it encompasses the prerequisite for utilising halal ingredients in producing the final product. Furthermore, there is a growing trend in the use of emulsifiers as a key ingredient in food and non-food products, which raises concerns about their prevalence, origin and impact on consumers' health. This research aims to investigate the level of knowledge and awareness among the community in Brunei Darussalam about the presence, source and health consequence of emulsifiers in food and non-food items. A quantitative approach was executed in this study. A questionnaire was developed and made available online for distribution to the general public of Brunei Darussalam via social media platforms. The data obtained from participants was recorded and analysed using SPSS Statistics version 23. Overall, the sample population was predominantly comprised of females, youths of aged 18-24 years old, students, individuals with a Bachelor's degree and Muslims. The results showed that the participants, particularly females and current students were significantly more knowledgeable of emulsifiers in food than non-food products. However, the overall knowledge degree of the ingredient among the participants was moderate. Furthermore, most responses exhibited a poor awareness level regarding the sources of emulsifiers and an uncertainty of their effects on human health. In conclusion, the findings of the present study will benefit consumers, particularly Muslims in Brunei Darussalam, to make informed decision on their purchasing of products as the information provided in the research enables them to distinguish between halal and non-halal products.
Level of knowledge of FIKES students (Faculty of Health Sciences) Muhammadiyah Lamongan University about halal skincare products
Authors: Fiely Fawwas , Handayani Riana Prastiwi , Yuliandhari Rully , Kusumo Djati Wulan
Published: August 2024

The majority of the religion adhered to by the population in Indonesia is Islam, where in Islam it has been ordered to all Muslims to consume, utilize and use something that is halal and also good including skincare. Skincare is a product of skin care outside the body with certain functions. However, people's knowledge of using halal skincare is still low, this is evidenced by the fact that they are still allowed to use skincare that does not have halal certification because these products are commonly used. This study aims to determine the level of knowledge of students of the Faculty of Health Sciences (FIKES) Muhammadiyah Lamongan University about halal skincare. This study used a descriptive observational research design, and the sample for this study was 2022 FIKES students, a total of 390 students. Sampling technique using purposive sampling. The instrument used was a closed questionnaire in the form of Google form. The results showed that the knowledge level of FIKES students about halal skincare was in the good category of 47.69%, the sufficient category was 46.16%, the less category was 6.15%. It can be concluded that the knowledge level of FIKES students at Muhammadiyah Lamongan University about halal skincare is in the good category.
Review of the all-you-can-eat restaurant concept based on Islamic business ethics to assist the development of the national halal ecosystem
Authors: Muhammad Zaydan , Maghfuroh Nuril Laila , Qanita Ariza
Published: August 2024

All you can eat is a restaurant or restaurant service that has a menu sales system based on only one payment for all available menus with a buffet or buffet concept with a certain time limit. In Indonesia, many restaurants or places to eat have provided all you can eat because of the pretext of attracting customers and increasing turnover. However, there are still many places to eat that provide non-halal menus that are contrary to Indonesia's vision as a global halal center in 2024. In this study, a qualitative descriptive method was used with literature and Islamic business ethics as a supporting study. The purpose of this study is to conceptually describe all you can it in accordance with Islamic business ethics and support the creation of a halal ecosystem in Indonesia. So that it can produce research output that can be used as a reference later for restaurants or restaurants that provide an all you can it menu that is in accordance with the principles of Islamic business ethics and still maintains halal status.
Geomorphological Compartmentation of Pereiro Massif and its surroundings, in Northern Northeast of Brazil
Authors: Albuquerque Diêgo Souza , Xavier Rafael Albuquerque , Suertegaray Dirce Maria Antunes
Published: August 2024

The Pereiro Massif (PM), located between the states of Ceará, Rio Grande do Norte and Paraíba, is a granitoid body that occupies an area of ​​approximately 2,200 km2, and and has maximum altitudes of 861 meters. This work aimed to elaborate and discuss the geomorphological compartmentalization of the Pereiro Massif and its surroundings. To this end, the following procedures were followed: 1) bibliographic and cartographic review on the geology and relief of the study area; 2) creation of the geomorphological map in a GIS environment, through SRTM image processing; 3) field activities for mapping conference, obtaining information to characterize the shapes and photographic survey. Fifteen units were mapped and grouped into three dimensions that consider the resulting processes and forms: accumulation, flattening and erosion surfaces. The compartments are classified recognizing processes associated with continental denudation with erosion, transport and deposition of material, based on structural geomorphology. The mapping carried out enhances the scientific notoriety of the PM and is expected to serve for environmental planning actions, such as the creation of protected areas and environmental licensing procedures.
Exploring the effectiveness of employee engagement strategies in the manufacturing industry: a South African perspective
Authors: Mabotja Tshepo , Cele Cyprian , Mavutha Winiswa
Published: August 2024

The paint manufacturing sector has not received sufficient attention, having its unique challenges with employee engagement, despite numerous investigations on employee engagement in several industries. This study seeks to address this deficiency by performing a targeted investigation on the levels of employee involvement within the paint manufacturing sector. This study aims to assess the level of employee involvement in the paint manufacturing industry in South Africa. This study systematically assesses the strategies and practices of employee engagement implemented by paint manufacturing companies operating in the region. This study utilises a mixed methods approach and follows an exploratory research design to accomplish its objectives. This methodology utilises many research techniques to provide a thorough understanding of the complex employee engagement processes in the paint manufacturing industry. The survey instrument, comprising of 320 questionnaires, was distributed to managerial professionals, human resource practitioners, and general employees working at paint production plants in South Africa. In addition to collecting quantitative data, interviews were undertaken to further enrich the depth of insights. The findings reveal a beneficial and interconnected link between the factors studied, suggesting a reciprocal strengthening that enhances employee engagement. Moreover, the study highlights the complex interconnection between the six aspects of employee involvement in the company environment. These characteristics jointly contribute to the fundamental aspects of employee engagement within paint manufacturing firms. Industry stakeholders should work together to develop an organisational culture that is deeply ingrained in the industry's identity and resonates with all personnel. One key remedy suggested is to conduct an employee engagement survey across the entire organisation, which will help gain a thorough understanding of engagement dynamics. This study highlights a strong association between employee engagement, departmental affiliation, racial demographics, and age groups. Therefore, organisations can improve workplace engagement by carefully taking into account the impact of departmental divisions, racial origins, and age cohorts on the overall engagement picture. The study's findings shed light on the significant influence of these factors in determining the dynamics of employee engagement.
Evaluating financial reporting guidelines in South African public schools
Authors: Ngcobo Sanele , Ndovela Sithembele Goodman
Published: August 2024

This paper aims to evaluate the different financial reporting guidelines used by governing bodies in public schools across 9 provinces. Therefore, developing an integrated financial reporting framework to improve accountability by SGBs that can be used by public schools in South Africa. This situation motivates the researcher to explore the lack financial reporting by SGBs in section 21 schools. The study also aimed to make recommendations to all stakeholders on how integrated financial reporting can promote accountability and transparency. The target population consisted of 56 section 21 schools in KwaZulu Natal province. A mixed methods approach was employed, and a questionnaire was developed and sent to participants using monkey survey. In addition, principals were interviewed one on one online using Microsoft Teams. SPSS version 25 was used to analyse the data, generating table and bar graphs. The findings revealed that the department of basic education should formulate the audit committee to monitor and evaluate financial statements of section 21 schools. The independent auditors should report back to the department of basic education not to the SGB to promote transparency and accountability. The study recommends that the current financial reporting structure can be improve by adopting integrated financial reporting framework where all stakeholders are actively involved. The Auditor General should audit the independent audit that are auditing section 21 schools and give an annual report on their performance.