bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospects for Using 3D Modeling and Biomarkers in Differential Diagnosis of Endometrioid Ovarian Cysts
Authors: Blazhnova Е. М. , Balter R. B. , Ivanova Т. V. , Pugacheva Т. А. , Ibragimova А. R. , Tselkovich L. S. , Oganisyan А. Т.
Published: June 2024

Background. Ovarian heterotopias are quite successfully diagnosed with ultrasound examinations. Considering the high risk of spread of the disease, as well as reproductive consequences (infertility, pelvic adhesive processes, chronic pelvic pain syndrome, dysmenorrhea), early differential diagnosis of endometrioid cysts and, accordingly, early initiation of treatment are of particular importance.Objective: to combine ultrasound criteria using 3D visualization and the content of biomarkers to verify stage 1–2 endometrioid ovarian cysts.Material and methods. In 59 infertile women with endometrioid ovarian cysts, in the dynamics of the menstrual cycle, ultrasound examinations were performed using Acuson S2000 (Siemens, Germany) and Voluson E8 (General Electric, USA) with the possibility of Doppler measurements and three-dimensional reconstruction of tissue images. Also, in laboratories “Invitro”, “Hemotest”, “Nauka” (Samara, Russia) the biomarkers were determined: interleukins IL-1β, IL-6, cancer antigen 125 (CA-125), human epididymis protein 4 (HE4) and the index by Risk of Ovarian Malignancy Algorithm (ROMA). The control group included 195 fertile women of reproductive age. In patients with endometrioid cysts, the diagnosis was subsequently confirmed morphologically.Results. Small unilateral and bilateral ovarian cysts corresponding to stage 1–2 endometriosis by revised American Fertility Society classification (rAFS) were clearly differentiated in 56 (94.9%) patients, in 3 (5.4%) of them the ultrasound result was questionable. In 48 (81.4%) women the lesion was unilateral and in 11 (18.6%) it was bilateral. The structure of cystic formations in all cases was hypoechoic, heterogeneous, in 36 (61.0%) cases it was finely cellular, without blood flow.Conclusion. Ovarian endometriomas in “gray scale” are round formations of reduced echogenicity and fine suspension, with an even, clear contour, not fused with the surrounding tissues, avascular, changing size depending on menstrual cycle phase. An ovarian mass may have a capsule with locus signals on Doppler. The sensitivity of ultrasound examination in “gray scale” in the presence of an endometrioid cyst is 94.6%.
Intellectual influence of smart tourism destinations 2000-2023
Authors: PALOMO SANTIAGO Miguel , PARRA LÓPEZ Eduardo
Published: June 2024

Purpose - This paper conducts a meticulous bibliometric analysis of 659 documents indexed in the Web of Science database, exploring the intellectual evolution of Smart Tourism Destinations (STD) and contributing to understanding the evolution of scientific literature on STD until December 2023, guiding future explorations in this dynamic and evolving field. Methodology/Design/Approach - By unifying the conceptual structure and highlighting key descriptive elements with the application of statistical methods, this research provides insights into the intellectual fabric of STD research. Findings - Our findings show the evolution of the conceptual structure, influential authors, institutions and countries involved in STD research, as well as the evolving social structure within the field. The surge in scientific output, especially since 2019 aligns with the integration of advanced technologies, including artificial intelligence, immersive mechanisms, big data, and robotics, prompting uncertainty in business implementation and stakeholder responses. Originality of the research - This study sheds light on the intellectual evolution of STD by summarising a wide range of literature, helping the authors to be informed about future research directions in the field.
SPA INDUSTRY RESILIENCE IN CHANGING EXTERNAL CONDITIONS: NEXUS BETWEEN TOURIST ATTRACTIVENESS AND FISCAL POLICY
Authors: NOVOTNÁ Markéta , HALÁMEK Petr , TÓTHOVÁ Dominika
Published: June 2024

Purpose – This study aims to evaluate the performance of the Czech spa industry within a dynamically changing external environment, specifically in the context of the COVID-19 pandemic. Considering the relationship between tourist attractiveness and fiscal policy effectiveness, the research explores the divergences existing among spa companies functioning across discrete spa resort categories within the Czech Republic. Methodology/Design/Approach – The research employs secondary data obtained from the State Statistical Office and the Business Register. The analysis entails an examination of the relationship between the level of tourist attractiveness and alterations in sales. Findings – The study reveals that spa resorts with higher levels of tourist attractiveness encountered a more pronounced decline in sales. Despite the notable allocation of public funds, the impact of subsidies on economic outcomes remained limited. Originality of the research – A contribution lies in its revelation of the adverse implications of over-reliance on tourism for the spa industry. The study highlights the imperative for diversification in resort portfolios. Moreover, the research offers valuable insights into the optimal allocation of subsidies, suggesting directions for more effective utilization and distribution in a manner that supports the industry's long-term sustainability and resilience.
Sustainability challenges in medical equipment donations to low- and middle-income countries
Authors: Ojo Olumide , Waheed Hajra
Published: June 2024

Access to medical equipment (ME) is an essential component of the healthcare infrastructure. Due to the high manufacturing cost, low- and middle-income countries (LMICs) rely on donations from high-resource settings to meet their demand for ME. International organizations such as the World Health Organization (WHO) have prescribed guidelines for sustainable donations. A few research studies have assessed current donation practices’ compliance with new and used ME. This study aims to investigate commonly recurring challenges and compile practical recommendations for ME donation programs in LMICs. To validate the findings from the literature review, semi-structured interviews were conducted with three different types of recipients across Pakistan and Sierra Leone. There are some obstacles affecting this sustainable ME donation program. These hurdles can be overcome by strict compliance with the official WHO guidelines, empowering the recipient through communication and policy, establishing vital metrics, and developing sustainable long-term donor-recipient relationships, and by comprehensive evaluation of the impact of all the stakeholders in the ME ecosystem. This study concludes that well-established guidelines and policies are critical to successful ME donation programs.
The model of continuous photon scattering in jne-dimensional approximation
Authors: Berezin Andrei Vsevolodovich , Volkov Yuri Aleksandrovich , Kazymov Shamil Adil Ogly , Markov Mikhail Borisovich , Tarakanov Ilya Alekseyevich
Published: June 2024

The scattering of photons in a homogeneous target is considered. An algorithm for the numerical solution of the one-dimensional photon transport equation in the approximation of one collision at a step in space is presented. In the approximation of average energy losses, an algorithm has been constructed for calculating the current density and energy release of recoil electrons formed during photon scattering. The effectiveness of the models is examined by comparing them with the results of full 3D transport simulations and direct collision simulations.
ANALYSIS OF CAR OPERATING COSTS
Authors: Ahapov Oleh , Pelypenko Yevhen
Published: June 2024

The paper considers a general approach to determining the cost of car ownership, including the costs of entry into ownership, the costs of operation and the costs of exit from ownership. Particular attention is paid to real operating costs, which were taken into account on the example of a particular car over a fairly long period of time. On the basis of their analysis, the items of expenditure and the degree of influence of each of them were identified. In operating costs, the most important items are those related to the purchase of fuel and storage of the car, while in the total cost of ownership - the loss of value of the car for the period under consideration and operating costs.
Based on the obtained data, specific indicators characterising the total cost of vehicle ownership were determined, which explain the growing tendency, especially in large cities, to reduce the number of personally owned cars due to economic inexpediency, and, as a consequence, the active development of alternative forms of transport service organisation
Peningkatan Kompetensi Guru Madrasah dalam Membelajarkan Peserta Didik Berkebutuhan Khusus
Authors: Suprihatin Suprihatin
Published: June 2024

Artikel ini melaporkan tentang kegiatan upaya peningkatan keterampilan mengajar guru madrasah yang tergabung dalam Kelompok Kerja Madrasah Ibtidaiyah (KKMI) Jakarta Timur yang sebagian besar masih belum memahami dengan baik tentang apa, siapa, mengapa dan bagaimana peserta didik berkebutuhan khusus, pendidikan inklusif dan pelaksanannya. Tujuan kegiatan ini adalah untuk meningkatkan kesadaran dan pemahaman guru-guru madrasah ibtidaiyah tentang peserta didik berkebutuhan khusus, pendidikan inklusif dan pelaksanaannya. Metode yang digunakan adalah penyuluhan dan bimbingan teknis melalui aplikasi zoom meeting yang diikuti oleh 80 orang guru madrasah yang sekolahnya menerima peserta didik berkebutuhan khusus. Para guru terlihat sangat antusias mengikuti kegiatan yang dilaksanakan. Namun ada guru yang menyebut peserta didik berkebutuhan khusus sebagai ‘anak inklusif’ maka penyebutan ini perlu diluruskan sehingga pelabelan yang bersifat negatif terhadap para peserta didik tidak akan terjadi lagi.
PELATIHAN PEMBUATAN SABUN BATANG AMPAS KOPI BAGI WARGA SEKOLAH DI LINGKUNGAN MGMP KIMIA JAKARTA TIMUR 2
Authors: Suryani Elma
Published: June 2024

Kegiatan Pelatihan Pembuatan Sabun Batang Ampas Kopi yang dilakukan bertujuan untuk meningkatkan kompetensi para guru dalam menjalankan profesinya sehingga berdampak baik pada kegiatan pembelajaran di sekolah. Disamping itu guru-guru diharapkan juga mampu untuk mengembangkan keterampilannya dibidang sains yang nantinya dapat diterapkan dalam pembelajaran di kelas. Ampas kopi memiliki kandungan-kandungan yang baik untuk kulit seperti zat antioksidan yang cukup tinggi diantaranya flavonoid dan polifenol. Pengetahuan mengenai cara pembuatan sabun batang ampas kopi, sangat bisa mendatangkan keuntungan baik dari segi peluang usaha maupun menjaga kesehatan dan kebersihan diri. Oleh karena itu, perlu dilakukan pelatihan pembuatan sabun batang dengan memanfaatkan ampas kopi.  Pelatihan ini diikuti oleh 44 orang guru kimia yang tergabung dalam MGMP Kimia Jakarta Timur 2 dan terdiri dari beberapa kegiatan, yaitu edukasi terkait fungsi dari bahan-bahan yang digunakan dalam pembuatan sabun serta kategori kualitas sabun yang baik, praktek pembuatan sabun dengan metode cold process, diskusi interaktif tentang proses pembuatan sabun beserta cara penerapan praktikum di sekolah, dan diakhiri dengan pengisisan lembar evaluasi oleh peserta. Berdasarkan hasil lembar evaluasi, sebanyak 92,61% merasa puas dengan penyampaian materi, 94,32% menyatakan memperoleh wawasan dan pengetahuan baru, 86,93% menyatakan materi yang disajikan dapat diterapkan dalam pembelajaran kimia di sekolah, dan 88,07% menyatakan materi yang diajarkan memunculkan ide baru untuk melaksanakan pembelajaran interaktif di kelas. Peserta juga berharap pengabdian ini dapat dilaksanakan setiap tahunnya bahkan rata-rata menyatakan 5 kali dalam setahun.
Improving 4D Seismic History Matching Through Data Analysis: A Localized Sensitivity Analysis Workflow
Authors: Kolajoobi Rasool A. , MacBeth Colin , Landa Jorge
Published: June 2024

4D seismic history matching (4D SHM) uses 4D seismic data to calibrate reservoir models to reduce production forecast uncertainty and improve reservoir surveillance. 4D seismic becomes very valuable in field developments with sparse well configurations and high areal uncertainty, such as offshore and carbon sequestration projects. Unlike the production data, the conventional uncertainty and sensitivity analysis (SA) with 4D seismic data might return misleading results. Due to the smooth nature of 4D seismic data, it is highly likely that low-frequency signals dampen the impact of model parameters on high-frequency signals. Consequently, some significant parameters are wrongly excluded from the 4D SHM process. Our work aims to address this issue by localizing the SA of 4D seismic data. The idea is first to identify specific seismic signals on the seismic maps and then perform the SA only at the individual locations rather than the entire map. This way we overcome the dampening effects of low-frequency signals.

Several approaches to localize the SA are utilized. In one approach, we defined sliding windows to scan the seismic maps and then executed an SA inside the windows at each location. Other localization approaches employ dimensionality reduction and feature extraction tools. We used principal component analysis (PCA) and advanced machine learning methods such as autoencoders (AEs) and variational autoencoders (VAEs) to transform the 4D seismic maps into a latent space. The information content (the 4D seismic signals) in the high-dimensionality 4D seismic maps is represented by a few features in the latent space. Implementing an SA for each feature in the latent space is equivalent to performing SA with the seismic signals in the original map.

The localized SA scheme is coupled with the ensemble smoother with multiple data assimilation (ESMDA) algorithm to carry out 4D SHM. Three 4D SHM scenarios were defined as full parameterization with no SA, conventional SA using the entire map, and localized SA. We ran these scenarios for a complex synthetic reservoir model based on a real field in the North Sea to match 4D P-wave seismic impedance. The results confirmed the superiority of the localized SA scenario which returned the final ensemble with the lowest error and the best match among the three scenarios. It also turned out that the PCA, for this specific case, is the most suitable methodology to localize the SA.
Krylov complexity in a natural basis for the Schrödinger algebra
Authors: Patramanis Dimitrios , Sybesma Watse
Published: June 2024

We investigate operator growth in quantum systems with two-dimensional Schrödinger group symmetry by studying the Krylov complexity. While feasible for semisimple Lie algebras, cases such as the Schrödinger algebra which is characterized by a semi-direct sum structure are complicated. We propose to compute Krylov complexity for this algebra in a natural orthonormal basis, which produces a pentadiagonal structure of the time evolution operator, contrasting the usual tridiagonal Lanczos algorithm outcome. The resulting complexity behaves as expected. We advocate that this approach can provide insights to other non-semisimple algebras.
The Contribution of West Kalimantan Sufi Scholars In Promoting Community Resilience: The Great Works of The Sufis to Fulfill the Basic Needs of Societies
Authors: Elmansyah Elmansyah , Nurhadijah Elis , Gitosaroso Muh. , Sahri Sahri
Published: June 2024

West Kalimantan is known as a region that produces Sufism thought, which is widely developed and utilized in various areas in Indonesia and the world. It can be seen from their great works in the form of books and development applications that they have created, even in integrating congregations. This research aims to reveal the works of West Kalimantan Sufism Ulama related to their efforts to build social, national and state resilience. The study is carried out over a long period, from 2012 to 2021. Several articles have been published in scientific journals and in book form. The research was conducted using a biographical approach through stories about their activities, the books they wrote, and other works still useful today. The study results show that Sufism scholars in West Kalimantan have their way of responding to changing times. The results of this work can be applied to Indonesia, which continues to grow towards becoming a developed and authoritative country.
Emerging Multi-omic Approaches to the Molecular Diagnosis of Mitochondrial Disease and Available Strategies for Treatment and Prevention
Authors: Khaghani Faeze , Hemmati Mahboobeh , Ebrahimi Masoumeh , Salmaninejad Arash
Published: June 2024

:

Mitochondria are semi-autonomous organelles present in several copies within most
cells in the human body that are controlled by the precise collaboration of mitochondrial DNA
(mtDNA) and nuclear DNA (nDNA) encoding mitochondrial proteins. They play important roles
in numerous metabolic pathways, such as the synthesis of adenosine triphosphate (ATP), the predominant
energy substrate of the cell generated through oxidative phosphorylation (OXPHOS), intracellular
calcium homeostasis, metabolite biosynthesis, aging, cell cycles, and so forth. Previous
studies revealed that dysfunction of these multi-functional organelles, which may arise due to mutations
in either the nuclear or mitochondrial genome, leads to a diverse group of clinically and genetically
heterogeneous disorders. These diseases include neurodegenerative and metabolic disorders
as well as cardiac and skeletal myopathies in both adults and newborns. The plethora of
phenotypes and defects displayed leads to challenges in the diagnosis and treatment of mitochondrial
diseases. In this regard, the related literature proposed several diagnostic options, such as
high throughput mitochondrial genomics and omics technologies, as well as numerous therapeutic
options, such as pharmacological approaches, manipulating the mitochondrial genome, increasing
the mitochondria content of the affected cells, and recently mitochondrial diseases transmission
prevention. Therefore, the present article attempted to review the latest advances and challenges in
diagnostic and therapeutic options for mitochondrial diseases.
Design, Optimization, and Evaluation of Chitosan-2-mercaptobenzoic Acid
as a Dual-functionalized Thiomer
Authors: Marwaha Tejinder K. , Madgulkar Ashwini , Bhalekar Mangesh
Published: June 2024

Aims:

This study aimed to develop and evaluate mucoadhesive microspheres for the
controlled release of zidovudine using a novel dual-functionalized polymer.

Background:

Mucoadhesive polymers have recently been widely used to prolong the GI residence
time and to modulate the release impact of various mucoadhesive dosage forms. In the
present study, a recently synthesized chitosan derivative, chitosan-2-mercapto benzoic acid, was
used as a mucoadhesive polymer, which was further developed as a dosage form for improving
oral bioavailability of zidovudine drug.

Objective:

The objective of this study is to evaluate the impact of a novel thiolated derivative,
chitosan-2-mercaptobenzoic acid, on the oral bioavailability of the drug zidovudine.

Methods:

The microspheres were prepared using an emulsification crosslinking method with
TPP as the crosslinking agent. Techniques such as FTIR, and DSC were employed to analyze the
microspheres, along with drug content, entrapment efficiency, dissolution studies, mucoadhesion,
ex vivo permeation, and in vivo evaluations.

Results:

Results from FTIR spectroscopy and DSC analysis revealed no interaction between the
drug and polymers. The release kinetics and characterization assessments indicated a zero-order
release profile with anomalous and super case-II transport types. Ex vivo permeation studies on
goat intestinal mucosa demonstrated enhanced mucoadhesive properties and permeability with
the optimized microspheres fabricated using thiomers compared to conventional oral therapy.
Pharmacokinetic investigations showed higher zidovudine plasma levels and Cmax with the administration
of microspheres, particularly those composed of thiomers. The AUC0-24h values for
thiomer microspheres were significantly greater than controls and chitosan microspheres, indicating
improved oral bioavailability potential.

Conclusion:

In conclusion, zidovudine-loaded thiomer-based mucoadhesive microspheres
showed promising results with the ability to enhance the drug's oral bioavailability.
Strategi Transformasi Digital: Inovasi Program Tuka Tuku Purbalingga
Authors: Latifah Nur Laela Dian , Adzam Muh. , Vidiastuti Dwi Putri
Published: June 2024

Pergeseran ke arah digitalisasi telah menjadi faktor utama dalam kemajuan berbagai sektor kehidupan pada zaman modern ini. Salah satu sektor yang terkena dampaknya adalah pemerintahan daerah, dengan Program Tuka Tuku Purbalingga menjadi contoh nyata penerapan inovasi digital untuk meningkatkan pelayanan publik dan memperkuat ekonomi lokal. Dalam menghadapi rendahnya minat Usaha Mikro, Kecil, dan Menengah (UMKM) terhadap program ini, penelitian ini bertujuan untuk mengidentifikasi strategi yang perlu dilakukan untuk memperkenalkan Tuka Tuku sebagai platform penjualan produk secara digital bagi UMKM di Purbalingga. Melalui pendekatan kualitatif eksploratif, di mana penelitian kualitatif digunakan untuk menyelidiki fenomena yang ada di lapangan, metode purposive sampling digunakan untuk menentukan informan dalam penelitian ini. Analisis yang digunakan adalah Analisis Interaktif yang melibatkan pengumpulan data, reduksi, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa dari tiga strategi transformasi digital yang diidentifikasi menurut teori Wasterman, yaitu pengalaman pelanggan, proses operasional, dan model bisnis, belum semuanya diimplementasikan sepenuhnya dalam Program Tuka Tuku Purbalingga. Secara keseluruhan, penelitian ini menyimpulkan bahwa proses transformasi digital di kalangan UMKM di Purbalingga masih berada pada tahap awal. Meskipun ada langkah-langkah positif yang telah diambil, masih ada sejumlah tantangan yang harus dihadapi. Transformasi digital bukan hanya tentang pemanfaatan teknologi semata, tetapi juga melibatkan perubahan dalam pola pikir, model bisnis, dan peningkatan keterampilan yang diperlukan.
MAKEUP MODIFICATION QUEEN OF HEART IN THE FILM ALICE IN WONDERLAND AS CARNIVAL MAKEUP WITH PHYSIOGNOMY
Authors: Mahmudah Faizatul , Puspitasari Feny
Published: June 2024

Character make-up is not only a means in films to create fictional characters, but also a component in performing arts which plays a role in enhancing visual aesthetics, artistic expression and overall appeal in works of art such as carnivals, one example of which is the Queen of Heart character in the film Alice in Wonderland. The challenges in creating makeup based on fictional characters adapted using a physiognomy approach are an interesting discussion. The aim of this research is to create a modified design for the make-up of the Queen of Heart character as a carnival make-up with physiognomy. This research uses the content analysis method with the Miles and Huberman data analysis model. The adaptations made to the Queen of Heart's make-up were done without losing its distinctive characteristics so that the source of the idea can still be recognized even though it is displayed in a different make-up. Research and development of the source of the idea of Queen of Heart as carnival make-up carried out by researchers, resulting in similarities, differences, advantages and disadvantages of Queen of heart make-up in films with adaptations.
Enhancing research publication choices: A comparative study of journal recommender systems and their effectiveness
Authors:   MIS Department, College of Business, University of Jeddah, Jeddah, Saudi Arabia, Bouaguel Waad , Benyounes Nouha ,   LARODEC, ISG, University of Tunis, Tunis, Tunisia, Ncir Chiheb Eddine Ben ,   MIS Department, College of Business, University of Jeddah, Jeddah, Saudi Arabia
Published: June 2024

In recent years, there has been a rapid increase in the number of research papers being published, leading to what many feel is an overload of information. This makes it difficult for researchers to choose the right journal for their work. To help with this, journal recommender systems have been suggested as useful tools to help researchers find the most appropriate journals for their research. With so many journals, publishers, and recommender systems to choose from, deciding on the best one can be complicated. This decision depends on several factors, including the publisher, the scientific database, and the specific needs and preferences of the user. In this paper, we offer a detailed comparison of popular journal recommender systems, both theoretically and through experiments, to see how effective they are at making recommendations. We focus on how relevant and helpful these recommendations are. We also provide advice for researchers on how to make the most of these recommender systems to aid in their publishing process.
Transforming the Future of Digital Health Education: Redesign of a Graduate Program Using Competency Mapping
Authors: Mun Michelle , Chanchlani Sonia , Lyons Kayley , Gray Kathleen
Published: June 2024

Digital transformation has disrupted many industries but is yet to revolutionize health care. Educational programs must be aligned with the reality that goes beyond developing individuals in their own professions, professionals wishing to make an impact in digital health will need a multidisciplinary understanding of how business models, organizational processes, stakeholder relationships, and workforce dynamics across the health care ecosystem may be disrupted by digital health technology. This paper describes the redesign of an existing postgraduate program, ensuring that core digital health content is relevant, pedagogically sound, and evidence-based, and that the program provides learning and practical application of concepts of the digital transformation of health. Existing subjects were mapped to the American Medical Informatics Association Clinical Informatics Core Competencies, followed by consultation with leadership to further identify gaps or opportunities to revise the course structure. New additions of core and elective subjects were proposed to align with the competencies. Suitable electives were chosen based on stakeholder feedback and a review of subjects in fields relevant to digital transformation of health. The program was revised with a new title, course overview, course intended learning outcomes, reorganizing of core subjects, and approval of new electives, adding to a suite of professional development offerings and forming a structured pathway to further qualification. Programs in digital health must move beyond purely informatics-based competencies toward enabling transformational change. Postgraduate program development in this field is possible within a short time frame with the use of established competency frameworks and expert and student consultation.
Assessment of Sexual Violence Risk Perception in Men Who Have Sex With Men: Proposal for the Development and Validation of “G-Date”
Authors: Angelone D J , Mitchell Damon , Wells Brooke , Korovich Megan , Nicoletti Alexandra , Fife Dustin
Published: June 2024

Background

Sexual violence (SV) is a significant problem for sexual minorities, including men who have sex with men (MSM). The limited research suggests SV is associated with a host of syndemic conditions. These factors tend to cluster and interact to worsen one another. Unfortunately, while much work has been conducted to examine these factors in heterosexual women, there is a lack of research examining MSM, especially their SV risk perception. Further, MSM are active users of dating and sexual networking (DSN) mobile apps, and this technology has demonstrated usefulness for creating safe spaces for MSM to meet and engage partners. However, mounting data demonstrate that DSN app use is associated with an increased risk for SV, especially given the higher likelihood of using alcohol and other drugs before sex. By contrast, some researchers have demonstrated that DSN technology can be harnessed as a prevention tool for HIV; unfortunately, no such work has progressed regarding SV.

Objective

This study aims to (1) use qualitative and quantitative methods to tailor an existing laboratory paradigm of SV risk perception in women for MSM using a DSN mobile app framework and (2) subject this novel paradigm to a rigorous validation study to confirm its usefulness in predicting SV, with the potential for use in future prevention endeavors.

Methods

To tailor the paradigm for MSM, a team of computer scientists created an initial DSN app (G-Date) and incorporated ongoing feedback about the usability, feasibility, and realism of this tool from a representative sample of MSM. We used focus groups and interviews to assist in the development of G-Date, including by identifying relevant stimuli, developing the cover story, and establishing the appropriate study language. To confirm the paradigm’s usefulness, we are conducting an experimental study with web-based and face-to-face participants to determine the content, concurrent, and predictive validities of G-Date. We will evaluate whether certain correlates of SV informed by syndemics and minority stress theories (eg, history of SV and alcohol and drug use) affect the ability of MSM to detect SV risk within G-Date and how paradigm engagement influences behavior in actual DSN app use contexts.

Results

This study received funding from the National Institute on Alcohol Abuse and Alcoholism on September 10, 2020, and ethics approval on October 19, 2020, and we began app development for aim 1 immediately thereafter. We began data collection for the aim 2 validation study in December 2022. Initial results from the validation study are expected to be available after December 2025.

Conclusions

We hope that G-Date will enhance our understanding of factors associated with SV risk and serve as a useful step in creating prevention programs for this susceptible population.
Effects of Quercetin Fraction from Moringa oleifera Leaf Extract on Oxidative Markers and Histological Profile of Carotid and Coronary Arteries: An Experimental Animal Study
Authors: Subandi Subandi , Suroto Suroto , Purwanto Bambang , Wasita Brian , Soetrisno Soetrisno
Published: June 2024

Objectives: Stroke and coronary disease are mainly caused by atherosclerosis. Quercetin in Moringa oleifera leaf extract may protect against oxidative stress. This study aimed to determine the role of quercetin in improving dyslipidemia and inhibiting atherosclerosis onset using laboratory and histological examinations. Methods: This experimental laboratory study used a double-blind randomized sampling technique and a pre- and post-test control group design. Experimental animals were divided into the control and treatment groups that received quercetin at a dose of 25 mg/kg body weight and a high-fat diet for 10 weeks from January to March 2023. Results: The Friedman's test of the effect of quercetin administration on malondialdehyde (MDA), intercellular adhesion molecule (ICAM), C-reactive proteins (CRP), and low-density lipoprotein (LDL) levels revealed significant differences between the pre- and post-test. The Wilcoxon signed-rank test for the effect of quercetin administration on MDA levels revealed a significant difference in MDA levels after quercetin administration. Paired sample statistics revealed an average decrease in ICAM and CRP levels and an increase in LDL levels after quercetin administration. Cramer's V value demonstrated a strong relationship between quercetin administration and the intensity of the carotid and coronary arteries. A one-way analysis of variance indicated significant differences in the average sizes of the coronary and carotid arteries after quercetin administration. Conclusion: The quercetin fraction of M. oleifera leaves has a satisfactory therapeutic effect in an atherosclerotic rat model.
Advances in Quantitative and Qualitative Assessment of Collagen in Cutaneous Wound Healing
Authors: Santoso Clarissa Nadya , Widyantara K. Ariex , Kencana Nyoman Bayu Wisnu , Setyajati Flavia Domitila Erika , Setiawati Agustina
Published: June 2024

Wound healing treatment is a challenging strategy in skin drug delivery due to its complexities. During wound healing stages, fibroblast deposit extracellular matrix components, which majority is collagen. Fibrillar collagen, particularly collagen I, is the predominant skin collagen during the healing process. Collagen analysis is a crucial process in wound healing study since it indicates impairment process of collagen production such as scar formation which is aesthetically unwanted. Therefore, recent studies developed quantitative and qualitative evaluation of collagen fiber based on histological staining. Thus, a comprehensive discussion of those studies to provide an insight for pharmacists, dermatologists, and skin researchers to designate a precise assessment in wound healing process.
 
Keywords: skin, wound, collagen, assessment
Research on the Digital Pathways for the Protection and Inheritance of Intangible Cultural Heritage
Authors: Shi Xia , Li Hongyu
Published: June 2024

This study aims to explore how local vocational colleges in Yueyang, Hunan Province, protect and inherit Intangible Cultural Heritage (ICH) through digital means. By analyzing the current status and challenges of ICH protection and considering the development trends of digital technology, the study focuses on the unique role of vocational colleges in the digital protection of ICH. Using literature reviews, interviews, and case studies, the study proposes specific pathways for the digital protection of ICH in Yueyang, including the construction of digital archives, digital education and training, digital display and dissemination, and social participation and interaction. The study finds that vocational colleges have multiple advantages in ICH protection, such as resource integration, talent cultivation, and technology application. The application of digital means will effectively enhance the efficiency of ICH protection and the breadth of its dissemination. Finally, the paper proposes relevant policy recommendations and implementation strategies to provide theoretical and practical references for promoting the digital protection of ICH.
Reliability and Validity of the Chinese Version of the Threat Appraisal Questionnaire in Assessing Children and Adolescents
Authors: PAN Jiarui
Published: June 2024

This study introduces the Threat Appraisal Questionnaire for Children (TAQ-C) and examines its reliability and validity among Chinese children and adolescents. The TAQ-C was administered to 903 children and adolescents, with PSWQ-C, IUSC-12 and MASC used as criterion tools. After two weeks, 38 adolescents completed the TAQ-C retest. The revised Chinese version of the Threat Appraisal Questionnaire presents a three-factor structure, including perceived probability, perceived severity, and coping cost, comprising 36 items. The model fit indices were satisfactory (χ2/df=3.521, RMSEA=0.053, CFI=0.914, TLI=0.906, SRMR=0.048). Multigroup confirmatory factor analysis further demonstrated that the revised TAQ-C meets measurement invariance across genders. The TAQ-C scores showed significant correlations with the scores of the criterion questionnaires, indicating good criterion validity. The revised questionnaire demonstrated good reliability, with an overall alpha coefficient of 0.93 for the full scale, a retest reliability of 0.76, and alpha coefficients for the subscales ranging from 0.81 to 0.87. The retest reliability of the subscales ranged from 0.60 to 0.79. The revised Chinese version of the Threat Appraisal Questionnaire shows a three-factor structure and demonstrates overall good reliability and validity among Chinese children and adolescents.
Empowering Indian Women: Scrutinizing Major Constitutional Provisions & Legislations on Women’s Rights in Context
Authors: Dey Dr. Sadhan Kumar , Dey Dr. Alice
Published: June 2024

Women empowerment is a critical aspect to achieving gender equality, where both men and women have equal power and opportunities for education, healthcare, economic participation and personal development. Women empowerment is a critical aspect to achieving gender equality, where both men and women have equal power and opportunities for education, healthcare, economic participation and personal development. including accepting women's viewpoints or making an effort to seek them, raising the status of women through education, awareness, and literacy. Ultimately, no matter the age, women feel most empowered when they see women who are similar to them and easy to relate to. Characteristics like intelligence, success, and kindness are just a few examples that make women feel empowered. These characteristics can apply to any empowering woman, not just celebrities. The Article has applied Comparative study of legal parameters and practicalCase –Based Analysis (CSA) as Methods to delve deep into the issue of empowerment of Indian women in the legal framework created by Indian
Challenges for Media Management in Mongolia: Television in a Converged Environment
Authors: Maamuu Delgerjargal
Published: June 2024

This paper presents the modernity of Mongolian television media management. The aim is to examine changes in advertising, which is the main revenue source for television stations, and identify problems with financing. The large number of televisions that share the advertisement market creates conditions and demands to focus on quality and choice of products in order to win the competition in compliance with market law. As Mongolia's media landscape evolves, successful television management requires a dynamic and forward thinking approach that incorporates opportunities created by technological convergence while navigating complex regulatory and competitive landscapes. The emergence of the Internet has not only changed the viewing habits of TV viewers, revolutionized the business model of traditional TV, but also led to the development of information technology, and constantly spawned new types of TV media, such as digital TV, internet TV and mobile TV.
ONE APPROACH TO THE DEVELOPMENT AND APPLICATION OF ASSISTIVE MULTIMEDIA LEARNING TOOL IN WORK WITH CHILDREN WITH DEVELOPMENTAL DISABILITIES
Authors: Spasić Aleksandar , Babanić Nevena , Nikolić Jelena , Janković Dragan , Milenković Aleksandar
Published: June 2024

The possibility of applying modern multimedia technology as an assistive tool in working with children with learning disabilities is truly immense. The aim of this paper was twofold. Firstly, either to confirm or disprove a view that children with learning disabilities can accept educational content intended for the children of regular population and secondly, to design a learning tool, a multimedia video game especially developed for this occasion. The method of work consisted of the following phases: analysis of developmental limitations of a child and group in the kindergarten, selection of activities and suggestions of models of learning, design and development of the means for the realization of learning, working (playing) with the child in the group in several iterations and analysis of the obtained results. The results obtained indicate that the use of multimedia tools as a help in working with children with developmental disabilities can be crucial for achieving visible results in the mastering of topics usually intended for children of the regular population.
STATE OF HIGHER EDUCATION FOR SUSTAINABLE DEVELOPMENT IN THE REPUBLIC OF SERBIA
Authors: Prodović Milojković Biljana , Prodović Hadži Bojan , Krstović Marija
Published: June 2024

An important part of the general agreement on the importance of education in achieving the goals of sustainable development also refers to the function and responsibility of the University. In this context, in recent years, much attention has been paid to advancing the process of integrating sustainability in universities, which is accompanied by the adoption of a transformative approach, linking theoretical with practical discourse and exploring new applications within and between scientific disciplines. The paper will present the concept of sustainable development in the context of education, with special emphasis on the presentation of education for sustainable development in the educational systems of Serbia. The focus of the paper is the analysis of the state of sustainable development in academic education in our country. The aim was to examine the extent to which education for sustainable development is represented at the faculties of social sciences and humanities of the University of Serbia. The selected methodology was based on the content analysis of the curriculum and syllabus with interviews with professors and assistants of selected faculties. Given that professors have been identified as bearers of education for sustainable development, the key to educating students for sustainable development is, and must be, in the education and continuous training of pedagogical staff in this field.
REFLECTIVE AND MENTORING PRACTICE - CONDITIONED SEGMENTS OF TEACHING
Authors: Milanović Aleksandra
Published: June 2024

Upon completing their initial education, teachers acquire mostly theoretical knowledge and learn how to teach. Whether a teacher will be good and professional depends on the way he works, on whether he continuously improves his knowledge and his competences. Mentoring practice and a reflective approach to professional work are two important segments of a teacher's work with a reciprocal impact on his experience, knowledge and teacher development. The aim of this paper is to highlight the importance of mentoring and reflective practice for teacher education and advancement. In order to achieve this goal, we first define the concept of mentoring and its significance for teacher work; we highlight the types of mentoring; we emphasize the benefits of reflective practice in teaching and finally identify common features of teacher mentoring and reflective practice. The conclusion is that these two segments of teaching - mentoring and reflective practice - are the twoskills that experienced,but also future teachers should have.
THE ANALYSIS OF TEACHER LEADERSHIP STYLES – PERCEPTIONS OF SECONDARY SCHOOL STUDENTS
Authors: Jovanović Dragana
Published: June 2024

The aim of this research was to determine which leadership style is perceived as the most dominant by the secondary school students, when the teachers' behaviours are presented through transformational, transactional and passive-avoidant leadership components. The perception of teacher leadership styles was also investigated in relation to various socio-demographic parameters. A total number of 500 secondary school students of final grade from Nis in the Republic of Serbia, participated in the research. Since this research was based on Transformational and Transactional Theories, information about teacher leadership style and leadership factors was collected through the adapted Multifactor Leadership Questionnaire - MLQ (Avolio & Bass, 2004). The research results indicate that, according to the students' perceptions, secondary school teachers practice both transactional as well as transformational leadership style, i.e., in the schools covered by the research a full range leadership model is articulated. Also, the research confirmed that variables such as gender, school type, educational profile, academic performance of the participants affect the perception of teachers' leadership styles.
Pensamiento artístico contemporáneo
Authors: Vargas Carlos , Tapia Ruiz Victoria , de León Francisco , Hernández Donovan Adrián
Published: June 2024

A lo largo de la última década, la Coordinación de Difusión Cultural de la UNAM ha ofrecido al público una amplia gama de actividades artísticas que van desde la experimentación y la vanguardia, hasta diversas aproximaciones hacia el fenómeno artístico. Producto de esta actividad es la edición de este libro Pensamiento artístico contemporáneo, en el cual los autores reflexionan, con profundidad y claridad, sobre sus perspectivas y expectativas en torno a las artes escénicas, musicales, literarias y cinematográficas. Sin duda, la presente obra ofrece un amplio espectro temático para toda persona interesada en los diálogos multidisciplinarios que sin perder el rigor conceptual, establecen puentes y vínculos cercanos entre las distintas disciplinas
Pengaruh Umur Bibit dan Pupuk Kotoran Sapi Terhadap Tanaman Sawi (Brassica juncea L.) di Lahan Kering
Authors: - Usmadi , Restiani Sih Harsanti
Published: June 2024

Limited water availability and soil organic matter are the main causes of low dry land productivity and are the main challenges in efforts to develop them. Green mustard plants, which have a short harvest period and are quite adaptable to the environment, are suitable for development in dry land and are expected to reduce the risk of crop failure due water deficit.  One source of organic material that is easily available at the farmer level is cow dung manure. This fertilizer is also able to help provide nutrients, increase the availability of moisture and microorganisms in the soil. It is hoped that the combination of the use of cow dung manure with mustard plants can be an afternative solution  and efforts to increase the productivity of dry land. The research aims to determine the possibility of using cow dung as a source of organic fertilizer in the cultivation of green mustard on dry land. The research is based on a Randomized Block Design consisting of nine treatments with four replications. Treatments included a combination  of different ages of seedlings without cow dung manure as a control; difference in seed age with 7.5 tons Ha-1 of cow dung manure and difference in seed age with 15 tons Ha-1 of cow dung manure. The data obtained were analyzed using variance and if there were significant differences, it was continued with the HSD test at the 5% level. The research result showed that applying cow dung manure can increase the growth and yield of green mustard on dry land. Seedlings aged 10 days after showing combined with the addition of 15 tons Ha-1 of cow dung manure can produce a fresh weight of 21.15 tons Ha-1 or 95.56% of the average potential productivity