bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Methods, Table 1, Figures 1-8 from Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes
Authors: Majumder Sarmila , Roy Satavisha , Kaffenberger Thomas , Wang Bo , Costinean Stefan , Frankel Wendy , Bratasz Anna , Kuppusamy Periannan , Hai Tsonwin , Ghoshal Kalpana , Jacob Samson T.
Published: April 2023

Supplementary Methods, Table 1, Figures 1-8 from Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes
Supplementary Figure 2 from Identification of Anaplastic Lymphoma Kinase as a Potential Therapeutic Target in Ovarian Cancer
Authors: Ren Hong , Tan Zhi-Ping , Zhu Xin , Crosby Katherine , Haack Herbert , Ren Jian-Min , Beausoleil Sean , Moritz Albrecht , Innocenti Gregory , Rush John , Zhang Yi , Zhou Xin-Min , Gu Ting-Lei , Yang Yi-Feng , Comb Michael J.
Published: April 2023

PDF file - 50K, Hyperphosphorylation of signaling molecules in serous carcinomas bearing ALK
Supplementary Figure 1 from Polycomb Protein EZH2 Regulates Tumor Invasion via the Transcriptional Repression of the Metastasis Suppressor RKIP in Breast and Prostate Cancer
Authors: Ren Gang , Baritaki Stavroula , Marathe Himangi , Feng Jingwei , Park Sungdae , Beach Sandy , Bazeley Peter S. , Beshir Anwar B. , Fenteany Gabriel , Mehra Rohit , Daignault Stephanie , Al-Mulla Fahd , Keller Evan , Bonavida Ben , de la Serna Ivana , Yeung Kam C.
Published: April 2023

PDF file, 267KB, Supplementary figure 1. a) Heat maps of RKIP, EZH2, Snail and E-cad expression profiles obtained by interrogating publicly available DNA microarray expression datasets (33). The abbreviations are as follows: NAP: normal adjacent prostate tissue, BPH: benign prostate hyperplasia, PCA: prostate cancer adenocarcinoma, and MPC: metastatic prostate carcinoma. Rows correspond to individual genes and columns represent individual patients. Color density is arranged in order from greatest decrease in expression at left (red) to greatest increase at right (light yellow). EZH2 and Snail mRNA are strongly expressed in MPC, in contrast to RKIP and E-cad. b) DU145 or MDA-MB231 cells were infected with indicated siRNA expressing retroviruses. The siRNA expressing cells were assayed for their ability to proliferate in growth medium containing 0.3% agar and the formation of multi-cellular colonies. Colonies were stained with MTT and quantified after 21 days from plates in triplicate (lower panel). Data shown are representative of three independent experiments and are expressed as mean colony number per plate +/- s.d. c) The effect of the indicated siRNA on DU145 cells proliferation was assayed by direct cell counting. Quiescent cells were counted by coulter counter at the indicated times after stimulation with 20% FBS. Data shown are representative of three independent experiments.
Supplementary Figure 5 from A Comprehensive View of Nuclear Receptor Cancer Cistromes
Authors: Tang Qianzi , Chen Yiwen , Meyer Clifford , Geistlinger Tim , Lupien Mathieu , Wang Qian , Liu Tao , Zhang Yong , Brown Myles , Liu Xiaole Shirley
Published: April 2023

PDF file - 582K
Supplementary Figure 4 from A Comprehensive View of Nuclear Receptor Cancer Cistromes
Authors: Tang Qianzi , Chen Yiwen , Meyer Clifford , Geistlinger Tim , Lupien Mathieu , Wang Qian , Liu Tao , Zhang Yong , Brown Myles , Liu Xiaole Shirley
Published: April 2023

PDF file - 691K
Supplementary Table 2 from Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
Authors: Suzuki Hiromu , Takatsuka Shintaro , Akashi Hirofumi , Yamamoto Eiichiro , Nojima Masanori , Maruyama Reo , Kai Masahiro , Yamano Hiro-o , Sasaki Yasushi , Tokino Takashi , Shinomura Yasuhisa , Imai Kohzoh , Toyota Minoru
Published: April 2023

Supplementary Table 2 from Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
Supplementary Table 1 from Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
Authors: Suzuki Hiromu , Takatsuka Shintaro , Akashi Hirofumi , Yamamoto Eiichiro , Nojima Masanori , Maruyama Reo , Kai Masahiro , Yamano Hiro-o , Sasaki Yasushi , Tokino Takashi , Shinomura Yasuhisa , Imai Kohzoh , Toyota Minoru
Published: April 2023

Supplementary Table 1 from Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
Supplementary Figure 10 from A Comprehensive View of Nuclear Receptor Cancer Cistromes
Authors: Tang Qianzi , Chen Yiwen , Meyer Clifford , Geistlinger Tim , Lupien Mathieu , Wang Qian , Liu Tao , Zhang Yong , Brown Myles , Liu Xiaole Shirley
Published: April 2023

PDF file - 965K
Supplementary Figure 1 from A Comprehensive View of Nuclear Receptor Cancer Cistromes
Authors: Tang Qianzi , Chen Yiwen , Meyer Clifford , Geistlinger Tim , Lupien Mathieu , Wang Qian , Liu Tao , Zhang Yong , Brown Myles , Liu Xiaole Shirley
Published: April 2023

PDF file - 645K
Supplementary Figure 2 from TLR3 as a Biomarker for the Therapeutic Efficacy of Double-stranded RNA in Breast Cancer
Authors: Salaun Bruno , Zitvogel Laurence , Asselin-Paturel Carine , Morel Yannis , Chemin Karine , Dubois Clarisse , Massacrier Catherine , Conforti Rosa , Chenard Marie Pierre , Sabourin Jean-Christophe , Goubar Aicha , Lebecque Serge , Pierres Michel , Rimoldi Donata , Romero Pedro , Andre Fabrice
Published: April 2023

Supplementary Figure 2 from TLR3 as a Biomarker for the Therapeutic Efficacy of Double-stranded RNA in Breast Cancer
Supplementary Methods from MIF Produced by Bone Marrow–Derived Macrophages Contributes to Teratoma Progression after Embryonic Stem Cell Transplantation
Authors: Wang Xi , Chen Tianxiang , Leng Lin , Fan Jianqing , Cao Kai , Duan Zhaoxia , Zhang Xijing , Shao Changshun , Wu Mingmei , Tadmori Iman , Li Tianyi , Liang Li , Sun Dongming , Zheng Shusen , Meinhardt Andreas , Young Wise , Bucala Richard , Ren Yi
Published: April 2023

PDF file - 103K
Supplementary Figure 2 from MIF Produced by Bone Marrow–Derived Macrophages Contributes to Teratoma Progression after Embryonic Stem Cell Transplantation
Authors: Wang Xi , Chen Tianxiang , Leng Lin , Fan Jianqing , Cao Kai , Duan Zhaoxia , Zhang Xijing , Shao Changshun , Wu Mingmei , Tadmori Iman , Li Tianyi , Liang Li , Sun Dongming , Zheng Shusen , Meinhardt Andreas , Young Wise , Bucala Richard , Ren Yi
Published: April 2023

PDF file - 100K, ESCs recruit bone marrow-derived macrophages
Supplementary Figure Legends 1-6 from Autocrine CSF-1 and CSF-1 Receptor Coexpression Promotes Renal Cell Carcinoma Growth
Authors: Menke Julia , Kriegsmann Jörg , Schimanski Carl Christoph , Schwartz Melvin M. , Schwarting Andreas , Kelley Vicki R.
Published: April 2023

PDF file - 66K
Supplementary Figure 1 from MIF Produced by Bone Marrow–Derived Macrophages Contributes to Teratoma Progression after Embryonic Stem Cell Transplantation
Authors: Wang Xi , Chen Tianxiang , Leng Lin , Fan Jianqing , Cao Kai , Duan Zhaoxia , Zhang Xijing , Shao Changshun , Wu Mingmei , Tadmori Iman , Li Tianyi , Liang Li , Sun Dongming , Zheng Shusen , Meinhardt Andreas , Young Wise , Bucala Richard , Ren Yi
Published: April 2023

PDF file - 103K, Deletion of MIF from the host inhibits teratoma development
Supplementary Figure 5 from Autocrine CSF-1 and CSF-1 Receptor Coexpression Promotes Renal Cell Carcinoma Growth
Authors: Menke Julia , Kriegsmann Jörg , Schimanski Carl Christoph , Schwartz Melvin M. , Schwarting Andreas , Kelley Vicki R.
Published: April 2023

PDF file - 877K
Supplementary Tables 1-4 from Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
Authors: Lou Yuanmei , McDonald Paul C. , Oloumi Arusha , Chia Stephen , Ostlund Christina , Ahmadi Ardalan , Kyle Alastair , auf dem Keller Ulrich , Leung Samuel , Huntsman David , Clarke Blaise , Sutherland Brent W. , Waterhouse Dawn , Bally Marcel , Roskelley Calvin , Overall Christopher M. , Minchinton Andrew , Pacchiano Fabio , Carta Fabrizio , Scozzafava Andrea , Touisni Nadia , Winum Jean-Yves , Supuran Claudiu T. , Dedhar Shoukat
Published: April 2023

Supplementary Tables 1-4 from Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
Supplementary Figure 4 from Autocrine CSF-1 and CSF-1 Receptor Coexpression Promotes Renal Cell Carcinoma Growth
Authors: Menke Julia , Kriegsmann Jörg , Schimanski Carl Christoph , Schwartz Melvin M. , Schwarting Andreas , Kelley Vicki R.
Published: April 2023

PDF file - 3.2MB
Supplementary Figure 1 from Autocrine CSF-1 and CSF-1 Receptor Coexpression Promotes Renal Cell Carcinoma Growth
Authors: Menke Julia , Kriegsmann Jörg , Schimanski Carl Christoph , Schwartz Melvin M. , Schwarting Andreas , Kelley Vicki R.
Published: April 2023

PDF file - 1.1MB
Supplementary Tables 1-5 from Loss of Transcription Factor KLF5 in the Context of p53 Ablation Drives Invasive Progression of Human Squamous Cell Cancer
Authors: Yang Yizeng , Nakagawa Hiroshi , Tetreault Marie-Pier , Billig Janelle , Victor Noel , Goyal Abha , Sepulveda Antonia R. , Katz Jonathan P.
Published: April 2023

PDF file - 100K
Supplementary Figures 1-3 from Androgen-Independent Molecular Imaging Vectors to Detect Castration-Resistant and Metastatic Prostate Cancer
Authors: Jiang Ziyue Karen , Sato Makoto , Wei Liu H. , Kao Chinghai , Wu Lily
Published: April 2023

PDF file - 729K
Supplementary Figure Legends 1-9 from Loss of Transcription Factor KLF5 in the Context of p53 Ablation Drives Invasive Progression of Human Squamous Cell Cancer
Authors: Yang Yizeng , Nakagawa Hiroshi , Tetreault Marie-Pier , Billig Janelle , Victor Noel , Goyal Abha , Sepulveda Antonia R. , Katz Jonathan P.
Published: April 2023

PDF file - 90K
Supplementary Figure and Table Legends from ETV6-NTRK3–Mediated Breast Epithelial Cell Transformation Is Blocked by Targeting the IGF1R Signaling Pathway
Authors: Tognon Cristina E. , Somasiri Aruna M. , Evdokimova Valentina E. , Trigo Genny , Uy Evett E. , Melnyk Nataliya , Carboni Joan M. , Gottardis Marco M. , Roskelley Calvin D. , Pollak Michael , Sorensen Poul H.B.
Published: April 2023

Supplementary Figure and Table Legends from ETV6-NTRK3–Mediated Breast Epithelial Cell Transformation Is Blocked by Targeting the IGF1R Signaling Pathway
Supplementary Figure 6 from Loss of Transcription Factor KLF5 in the Context of p53 Ablation Drives Invasive Progression of Human Squamous Cell Cancer
Authors: Yang Yizeng , Nakagawa Hiroshi , Tetreault Marie-Pier , Billig Janelle , Victor Noel , Goyal Abha , Sepulveda Antonia R. , Katz Jonathan P.
Published: April 2023

PDF file - 633K
Supplementary Video 2 from Dishevelled 2 Signaling Promotes Self-Renewal and Tumorigenicity in Human Gliomas
Authors: Pulvirenti Teodoro , Van Der Heijden Maartje , Droms Leif A. , Huse Jason T. , Tabar Viviane , Hall Alan
Published: April 2023

AVI file - 3.3MB, Time-lapse live video microscopy showing morphological changes induced after Dvl2 depletion in U87 glioma cells.
Supplementary Figure Legends, Supplementary Tables 1-2 from Coactivation of AKT and β-Catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors
Authors: Stauffer Jimmy K. , Scarzello Anthony J. , Andersen Jesper B. , De Kluyver Rachel L. , Back Timothy C. , Weiss Jonathan M. , Thorgeirsson Snorri S. , Wiltrout Robert H.
Published: April 2023

Supplementary Figure Legends, Supplementary Tables 1-2 from Coactivation of AKT and β-Catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors
Supplementary Figure 2 from Coactivation of AKT and β-Catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors
Authors: Stauffer Jimmy K. , Scarzello Anthony J. , Andersen Jesper B. , De Kluyver Rachel L. , Back Timothy C. , Weiss Jonathan M. , Thorgeirsson Snorri S. , Wiltrout Robert H.
Published: April 2023

Supplementary Figure 2 from Coactivation of AKT and β-Catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors
Supplementary Figure 1 from Coactivation of AKT and β-Catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors
Authors: Stauffer Jimmy K. , Scarzello Anthony J. , Andersen Jesper B. , De Kluyver Rachel L. , Back Timothy C. , Weiss Jonathan M. , Thorgeirsson Snorri S. , Wiltrout Robert H.
Published: April 2023

Supplementary Figure 1 from Coactivation of AKT and β-Catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors
Supplementary Methods, Figures 1-4 from Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity
Authors: Salah Zaidoun , Melino Gerry , Aqeilan Rami I.
Published: April 2023

Supplementary Methods, Figures 1-4 from Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity
Supplementary Table 1 from Effect of Maternal and Postweaning Folic Acid Supplementation on Mammary Tumor Risk in the Offspring
Authors: Ly Anna , Lee Hanna , Chen Jianmin , Sie Karen K. Y. , Renlund Richard , Medline Alan , Sohn Kyoung-Jin , Croxford Ruth , Thompson Lilian U. , Kim Young-In
Published: April 2023

Supplementary Table 1 from Effect of Maternal and Postweaning Folic Acid Supplementation on Mammary Tumor Risk in the Offspring
Supplementary Table 1 from MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-β Signaling Pathway in Human Glioblastoma
Authors: Grzmil Michal , Morin Pier , Lino Maria Maddalena , Merlo Adrian , Frank Stephan , Wang Yuhua , Moncayo Gerald , Hemmings Brian A.
Published: April 2023

Supplementary Table 1 from MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-β Signaling Pathway in Human Glioblastoma
Supplementary Tables 1-2 from The Novel Metastasis Promoter Merm1/Wbscr22 Enhances Tumor Cell Survival in the Vasculature by Suppressing Zac1/p53-Dependent Apoptosis
Authors: Nakazawa Youya , Arai Hiroyuki , Fujita Naoya
Published: April 2023

Supplementary Tables 1-2 from The Novel Metastasis Promoter Merm1/Wbscr22 Enhances Tumor Cell Survival in the Vasculature by Suppressing Zac1/p53-Dependent Apoptosis
Supplementary Figure Legends 1-3 from The Novel Metastasis Promoter Merm1/Wbscr22 Enhances Tumor Cell Survival in the Vasculature by Suppressing Zac1/p53-Dependent Apoptosis
Authors: Nakazawa Youya , Arai Hiroyuki , Fujita Naoya
Published: April 2023

Supplementary Figure Legends 1-3 from The Novel Metastasis Promoter Merm1/Wbscr22 Enhances Tumor Cell Survival in the Vasculature by Suppressing Zac1/p53-Dependent Apoptosis
Supplementary Table 6 from Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel
Authors: Ahmed Ahmed Ashour , Wang Xiaoyan , Lu Zhen , Goldsmith Juliet , Le Xiao-Feng , Grandjean Geoffrey , Bartholomeusz Geoffrey , Broom Bradley , Bast Robert C.
Published: April 2023

XLS file - 51K
Supplementary Table 3 from Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel
Authors: Ahmed Ahmed Ashour , Wang Xiaoyan , Lu Zhen , Goldsmith Juliet , Le Xiao-Feng , Grandjean Geoffrey , Bartholomeusz Geoffrey , Broom Bradley , Bast Robert C.
Published: April 2023

XLS file - 28K
Supplementary Table 1 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Authors: Ruggiero Raúl A. , Bruzzo Juan , Chiarella Paula , di Gianni Pedro , Isturiz Martín A. , Linskens Susana , Speziale Norma , Meiss Roberto P. , Bustuoabad Oscar D. , Pasqualini Christiane D.
Published: April 2023

PDF file - 52K
Supplementary Figure 11 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Authors: Aoki Koji , Kakizaki Fumihiko , Sakashita Hiromi , Manabe Toshiaki , Aoki Masahiro , Taketo Makoto M.
Published: April 2023

Supplementary Figure 11 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Supplementary Figure 3 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Authors: Ruggiero Raúl A. , Bruzzo Juan , Chiarella Paula , di Gianni Pedro , Isturiz Martín A. , Linskens Susana , Speziale Norma , Meiss Roberto P. , Bustuoabad Oscar D. , Pasqualini Christiane D.
Published: April 2023

PDF file - 56K
Supplementary Table 3 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Table 3 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Conflict of Interest Form 1 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Authors: Ruggiero Raúl A. , Bruzzo Juan , Chiarella Paula , di Gianni Pedro , Isturiz Martín A. , Linskens Susana , Speziale Norma , Meiss Roberto P. , Bustuoabad Oscar D. , Pasqualini Christiane D.
Published: April 2023

Conflict of Interest Form 1 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Supplementary Figure 5 from MYB Is Essential for Mammary Tumorigenesis
Authors: Yu Miao Rebecca , Drabsch Yvette , Cross Ryan Stanley , Cheasley Dane , Carpinteri Sandra , Pereira Lloyd , Malaterre Jordane , Gonda Thomas J. , Anderson Robin L. , Ramsay Robert G.
Published: April 2023

PDF file - 998K, Extent of proliferation, MYB and ER�� expression in wt virgin mammary glands.
Supplementary Figure 3 from MYB Is Essential for Mammary Tumorigenesis
Authors: Yu Miao Rebecca , Drabsch Yvette , Cross Ryan Stanley , Cheasley Dane , Carpinteri Sandra , Pereira Lloyd , Malaterre Jordane , Gonda Thomas J. , Anderson Robin L. , Ramsay Robert G.
Published: April 2023

PDF file - 360K, Transgene expression driven by the MMTV promoter is not effected by the loss of MYB in the mammary gland.
Supplementary Materials and Methods from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Authors: Hu Weiguo , Ge Xiaowen , You Tao , Xu Ting , Zhang Jinyan , Wu Gongxiong , Peng Zhihai , Chorev Michael , Aktas Bertal H. , Halperin Jose A. , Brown Jennifer R. , Qin Xuebin
Published: April 2023

Supplementary Materials and Methods from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Supplementary Figure 5 from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Authors: Hu Weiguo , Ge Xiaowen , You Tao , Xu Ting , Zhang Jinyan , Wu Gongxiong , Peng Zhihai , Chorev Michael , Aktas Bertal H. , Halperin Jose A. , Brown Jennifer R. , Qin Xuebin
Published: April 2023

Supplementary Figure 5 from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Supplementary Figure 2 from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Authors: Hu Weiguo , Ge Xiaowen , You Tao , Xu Ting , Zhang Jinyan , Wu Gongxiong , Peng Zhihai , Chorev Michael , Aktas Bertal H. , Halperin Jose A. , Brown Jennifer R. , Qin Xuebin
Published: April 2023

Supplementary Figure 2 from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Supplementary Methods, Figure Legends 1-4, Table Legends 1-15 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Authors: Heemers Hannelore V. , Schmidt Lucy J. , Sun Zhifu , Regan Kevin M. , Anderson S. Keith , Duncan Kelly , Wang Dan , Liu Song , Ballman Karla V. , Tindall Donald J.
Published: April 2023

Supplementary Methods, Figure Legends 1-4, Table Legends 1-15 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Supplementary Figure 4 from TNF-α Promotes c-REL/ΔNp63α Interaction and TAp73 Dissociation from Key Genes That Mediate Growth Arrest and Apoptosis in Head and Neck Cancer
Authors: Lu Hai , Yang Xinping , Duggal Praveen , Allen Clint T. , Yan Bin , Cohen Jonah , Nottingham Liesl , Romano Rose-Anne , Sinha Satrajit , King Kathryn E. , Weinberg Wendy C. , Chen Zhong , Van Waes Carter
Published: April 2023

PDF file - 2.5MB, Modulating c-REL differentially affects cellular proliferation, and apoptosis in UM-SCC22A cells expressing increased ��Np63 and TAp73 with mtTP53.
Supplementary Figure 7 from Survivin-3B Potentiates Immune Escape in Cancer but Also Inhibits the Toxicity of Cancer Chemotherapy
Authors: Végran Frédérique , Mary Romain , Gibeaud Anne , Mirjolet Céline , Collin Bertrand , Oudot Alexandra , Charon-Barra Céline , Arnould Laurent , Lizard-Nacol Sarab , Boidot Romain
Published: April 2023

PDF file, 167K, S-3B expression increased with resistance acquisition.
Supplementary Table 4 from DNA Methylation-Mediated Repression of miR-886-3p Predicts Poor Outcome of Human Small Cell Lung Cancer
Authors: Cao Jianzhong , Song Yongmei , Bi Nan , Shen Jie , Liu Wenyang , Fan Jing , Sun Guogui , Tong Tong , He Jie , Shi Yuankai , Zhang Xun , Lu Ning , He Yinghua , Zhang Hongyu , Ma Kelong , Luo Xiaoying , Lv Lei , Deng Hui , Cheng Jing , Zhu Jingde , Wang Luhua , Zhan Qimin
Published: April 2023

PDF file - 40K, ECOG Performance Status.
Supplementary Data Figures 1-4 from CD38 in Hairy Cell Leukemia Is a Marker of Poor Prognosis and a New Target for Therapy
Authors: Poret Nicolas , Fu Qiangwei , Guihard Soizic , Cheok Meyling , Miller Katie , Zeng Gordon , Quesnel Bruno , Troussard Xavier , Galiègue-Zouitina Sylvie , Shelley Carl Simon
Published: April 2023

Supplementary Data Figures 1-4. Figure S1: Genomic localization of ZFN target sequences. Figure S2: DNA sequence of wild-type and mutant CD38 genes. Figure S3: Western blot analysis of CD38 protein expression from wild-type and mutant CD38 genes. Figure S4: Flow cytometric analysis of CD38 surface expression from wild-type and mutant CD38 genes.
Supplemental Figure S1 from PD-1/SHP-2 Inhibits Tc1/Th1 Phenotypic Responses and the Activation of T Cells in the Tumor Microenvironment
Authors: Li Jing , Jie Hyun-Bae , Lei Yu , Gildener-Leapman Neil , Trivedi Sumita , Green Tony , Kane Lawrence P. , Ferris Robert L.
Published: April 2023

Supplemental Figure S1. Variable expression levels of PD-L1 on HNSCC cells.
Supplementary Figure Legends from Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy
Authors: Hughes Russell , Qian Bin-Zhi , Rowan Charlotte , Muthana Munitta , Keklikoglou Ioanna , Olson Oakley C. , Tazzyman Simon , Danson Sarah , Addison Christina , Clemons Mark , Gonzalez-Angulo Ana Maria , Joyce Johanna A. , De Palma Michele , Pollard Jeffrey W. , Lewis Claire E.
Published: April 2023

Supplementary Figure Legends from Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy
Supplementary Table and Figure Legends from Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer
Authors: Peng Jin , Hamanishi Junzo , Matsumura Noriomi , Abiko Kaoru , Murat Kumuruz , Baba Tsukasa , Yamaguchi Ken , Horikawa Naoki , Hosoe Yuko , Murphy Susan K. , Konishi Ikuo , Mandai Masaki
Published: April 2023

Legends for Supplementary Tables S1-S4 and Supplementary Figures S1-S22.
Supplementary Figure S5 from Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
Authors: Taipaleenmäki Hanna , Browne Gillian , Akech Jacqueline , Zustin Jozef , van Wijnen Andre J. , Stein Janet L. , Hesse Eric , Stein Gary S. , Lian Jane B.
Published: April 2023

Supplementary Figure S5. Expression of exogenous miR-135 and miR-203 in orthotopically transplanted breast cancer.
Supplementary Methods and Reference from Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer
Authors: Peng Jin , Hamanishi Junzo , Matsumura Noriomi , Abiko Kaoru , Murat Kumuruz , Baba Tsukasa , Yamaguchi Ken , Horikawa Naoki , Hosoe Yuko , Murphy Susan K. , Konishi Ikuo , Mandai Masaki
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary Reference.
Supplementary Figure S4 from Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
Authors: Taipaleenmäki Hanna , Browne Gillian , Akech Jacqueline , Zustin Jozef , van Wijnen Andre J. , Stein Janet L. , Hesse Eric , Stein Gary S. , Lian Jane B.
Published: April 2023

Supplementary Figure S4. Delivery of miR-135 and miR-203 decrease the expression of CCL-7 and CXCL-12.
Supplementary Figure S2 from Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
Authors: Taipaleenmäki Hanna , Browne Gillian , Akech Jacqueline , Zustin Jozef , van Wijnen Andre J. , Stein Janet L. , Hesse Eric , Stein Gary S. , Lian Jane B.
Published: April 2023

Supplementary Figure S2. Runx2 and Runx2-targeting miRNAs are regulated in metastatic breast cancer cells and bone metastases.
Supplementary Figure Legends from Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
Authors: Taipaleenmäki Hanna , Browne Gillian , Akech Jacqueline , Zustin Jozef , van Wijnen Andre J. , Stein Janet L. , Hesse Eric , Stein Gary S. , Lian Jane B.
Published: April 2023

Supplementary Figure Legends. Legends for Supplementary Figures S1-S7.
Supplementary Table S7 from Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs
Authors: Hunter Francis W. , Young Richard J. , Shalev Zvi , Vellanki Ravi N. , Wang Jingli , Gu Yongchuan , Joshi Naveen , Sreebhavan Sreevalsan , Weinreb Ilan , Goldstein David P. , Moffat Jason , Ketela Troy , Brown Kevin R. , Koritzinsky Marianne , Solomon Benjamin , Rischin Danny , Wilson William R. , Wouters Bradly G.
Published: April 2023

Spearman correlation of expression of flavoproteins with TPZ metabolism in tumor cell lines.
Supplementary Table S4 from Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs
Authors: Hunter Francis W. , Young Richard J. , Shalev Zvi , Vellanki Ravi N. , Wang Jingli , Gu Yongchuan , Joshi Naveen , Sreebhavan Sreevalsan , Weinreb Ilan , Goldstein David P. , Moffat Jason , Ketela Troy , Brown Kevin R. , Koritzinsky Marianne , Solomon Benjamin , Rischin Danny , Wilson William R. , Wouters Bradly G.
Published: April 2023

List of shRNAs on the custom reductase library.
Supplemental Figure 4 from BH3 Inhibitor Sensitivity and Bcl-2 Dependence in Primary Acute Lymphoblastic Leukemia Cells
Authors: Alford Sarah E. , Kothari Anisha , Loeff Floris C. , Eichhorn Joshua M. , Sakurikar Nandini , Goselink Henriette M. , Saylors Robert L. , Jedema Inge , Falkenburg J.H. Frederik , Chambers Timothy C.
Published: April 2023

Supplemental Figure 4: Pro-apoptotic Bcl-2 family proteins are absent in β-actin immunoprecipitates.
Supplementary Table S3 from Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs
Authors: Hunter Francis W. , Young Richard J. , Shalev Zvi , Vellanki Ravi N. , Wang Jingli , Gu Yongchuan , Joshi Naveen , Sreebhavan Sreevalsan , Weinreb Ilan , Goldstein David P. , Moffat Jason , Ketela Troy , Brown Kevin R. , Koritzinsky Marianne , Solomon Benjamin , Rischin Danny , Wilson William R. , Wouters Bradly G.
Published: April 2023

Primer sequences for evaluating shRNA-mediated knockdown of POR by quantitative real-time PCR.
Supplementary Table S1 from Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs
Authors: Hunter Francis W. , Young Richard J. , Shalev Zvi , Vellanki Ravi N. , Wang Jingli , Gu Yongchuan , Joshi Naveen , Sreebhavan Sreevalsan , Weinreb Ilan , Goldstein David P. , Moffat Jason , Ketela Troy , Brown Kevin R. , Koritzinsky Marianne , Solomon Benjamin , Rischin Danny , Wilson William R. , Wouters Bradly G.
Published: April 2023

Suppliers of cell lines and composition of cell culture media.
Supplementary Methods and References from Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs
Authors: Hunter Francis W. , Young Richard J. , Shalev Zvi , Vellanki Ravi N. , Wang Jingli , Gu Yongchuan , Joshi Naveen , Sreebhavan Sreevalsan , Weinreb Ilan , Goldstein David P. , Moffat Jason , Ketela Troy , Brown Kevin R. , Koritzinsky Marianne , Solomon Benjamin , Rischin Danny , Wilson William R. , Wouters Bradly G.
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figures S1-S14 from Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs
Authors: Hunter Francis W. , Young Richard J. , Shalev Zvi , Vellanki Ravi N. , Wang Jingli , Gu Yongchuan , Joshi Naveen , Sreebhavan Sreevalsan , Weinreb Ilan , Goldstein David P. , Moffat Jason , Ketela Troy , Brown Kevin R. , Koritzinsky Marianne , Solomon Benjamin , Rischin Danny , Wilson William R. , Wouters Bradly G.
Published: April 2023

Evaluation of SN30000-induced bystander cell killing in a co-culture system (S1); SN30000 clonogenic survival curves for HT-29, PANC-1 cells and HKO1 (S2); Plating efficiency in HT-29, PANC-1 and HKO2 reductase screens (S3); Density distributions and correlations of reductase screen sequencing data (S4); Log2 enrichment factors of shRNAs significantly selected in the reductase screens (S5); Depletion of POR protein by shRNAs in PANC-1 and HT-29 cells (S6); Replicate SN30000 clonogenic survival assays performed in stably transduced HT-29 and PANC-1 cells (S7); Measurement of plating efficiency in HKO1 and HKO2 whole-genome screens (S8); Coincidence of shRNAs significantly selected (Z > 1.96) in HT-29 and PANC-1 reductase screens and the HKO1 genome-wide screen (S9); Validation of POR shRNAs and clonogenic survival following SN30000 treatment of POR-knockout HCT116 cells (S10); Spatial distribution of POR and CA-IX expression in tongue SCC (S11); Quantitation of POR and CA-IX expression in HNSCC (S12); POR IHC staining in isogenic xenografts used for method development (S13); POR mRNA expression and sequence variation in the TCGA HNSCC dataset (S14).
Supplemental material from Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry
Authors: Guenther Sabine , Muirhead Laura J. , Speller Abigail V.M. , Golf Ottmar , Strittmatter Nicole , Ramakrishnan Rathi , Goldin Robert D. , Jones Emrys , Veselkov Kirill , Nicholson Jeremy , Darzi Ara , Takats Zoltan
Published: April 2023

Supplemental material on model generation and data handling
Supplemental Table 1 from Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry
Authors: Guenther Sabine , Muirhead Laura J. , Speller Abigail V.M. , Golf Ottmar , Strittmatter Nicole , Ramakrishnan Rathi , Goldin Robert D. , Jones Emrys , Veselkov Kirill , Nicholson Jeremy , Darzi Ara , Takats Zoltan
Published: April 2023

Supplemental Table 1. Number of patients and samples per group and model.
Supplemental Figure 3 from Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry
Authors: Guenther Sabine , Muirhead Laura J. , Speller Abigail V.M. , Golf Ottmar , Strittmatter Nicole , Ramakrishnan Rathi , Goldin Robert D. , Jones Emrys , Veselkov Kirill , Nicholson Jeremy , Darzi Ara , Takats Zoltan
Published: April 2023

Supplemental Figure 3. Distribution of FA(20:2) in a) normal glandular tissue, b) grade 2 tumor with positive HR status and c) grade 3 tumor with negative HR status.
Supplemental Figure 1 from Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry
Authors: Guenther Sabine , Muirhead Laura J. , Speller Abigail V.M. , Golf Ottmar , Strittmatter Nicole , Ramakrishnan Rathi , Goldin Robert D. , Jones Emrys , Veselkov Kirill , Nicholson Jeremy , Darzi Ara , Takats Zoltan
Published: April 2023

Supplemental Figure 1. Association of metabolomic DESI MSI profiles of normal glandular and tumor tissue with tumor type.
Supplementary Methods from Carbonic Anhydrase IX Promotes Myeloid-Derived Suppressor Cell Mobilization and Establishment of a Metastatic Niche by Stimulating G-CSF Production
Authors: Chafe Shawn C. , Lou Yuanmei , Sceneay Jaclyn , Vallejo Marylou , Hamilton Melisa J. , McDonald Paul C. , Bennewith Kevin L. , Möller Andreas , Dedhar Shoukat
Published: April 2023

Supplementary Methods
Supplemental Figure S3 from Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
Authors: Neskey David M. , Osman Abdullah A. , Ow Thomas J. , Katsonis Panagiotis , McDonald Thomas , Hicks Stephanie C. , Hsu Teng-Kuei , Pickering Curtis R. , Ward Alexandra , Patel Ameeta , Yordy John S. , Skinner Heath D. , Giri Uma , Sano Daisuke , Story Michael D. , Beadle Beth M. , El-Naggar Adel K. , Kies Merrill S. , William William N. , Caulin Carlos , Frederick Mitchell , Kimmel Marek , Myers Jeffrey N. , Lichtarge Olivier
Published: April 2023

Supplemental Figure S3. Comparison of disruptive and truncating p53 classification systems in the training set.
Supplementary Methods, Figure Legends from The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies
Authors: Vangamudi Bhavatarini , Paul Thomas A. , Shah Parantu K. , Kost-Alimova Maria , Nottebaum Lisa , Shi Xi , Zhan Yanai , Leo Elisabetta , Mahadeshwar Harshad S. , Protopopov Alexei , Futreal Andrew , Tieu Trang N. , Peoples Mike , Heffernan Timothy P. , Marszalek Joseph R. , Toniatti Carlo , Petrocchi Alessia , Verhelle Dominique , Owen Dafydd R. , Draetta Giulio , Jones Philip , Palmer Wylie S. , Sharma Shikhar , Andersen Jannik N.
Published: April 2023

Supplementary Methods, Figure Legends
Supplementary Figure S1 from Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth
Authors: Ta Huy Q. , Ivey Melissa L. , Frierson Henry F. , Conaway Mark R. , Dziegielewski Jaroslaw , Larner James M. , Gioeli Daniel
Published: April 2023

Primer Sequences.
Supplementary Figure Legend from Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth
Authors: Ta Huy Q. , Ivey Melissa L. , Frierson Henry F. , Conaway Mark R. , Dziegielewski Jaroslaw , Larner James M. , Gioeli Daniel
Published: April 2023

Legend for Supplementary Figure S1.
Supplemental Figure 3 from miR30a Inhibits LOX Expression and Anaplastic Thyroid Cancer Progression
Authors: Boufraqech Myriem , Nilubol Naris , Zhang Lisa , Gara Sudheer Kumar , Sadowski Samira M. , Mehta Amit , He Mei , Davis Sean , Dreiling Jennifer , Copland John A. , Smallridge Robert C. , Quezado Martha M. , Kebebew Electron
Published: April 2023

Supplemental Figure 3. Effect of LOX inhibition on metastasis in vivo. Treatment of mice before and after tail vein injection with 8505c cells reduced metastasis in vivo. BAPN treatment was initiated either 24 hours before (upper panel, four mice) or after (lower panel, four mice) tail vein injection. On the left are representative tumor luminescence images of untreated and BAPN-treated mice. B, Representative images of cellular migration and invasion in ATC cell lines transfected with siLOX.
Supplemental Figure 1 from miR30a Inhibits LOX Expression and Anaplastic Thyroid Cancer Progression
Authors: Boufraqech Myriem , Nilubol Naris , Zhang Lisa , Gara Sudheer Kumar , Sadowski Samira M. , Mehta Amit , He Mei , Davis Sean , Dreiling Jennifer , Copland John A. , Smallridge Robert C. , Quezado Martha M. , Kebebew Electron
Published: April 2023

Supplemental Figure 1: RT-PCR assay for miR-30a expression in transfected cells by either miR-30a mimic (A) or miR-30a inhibitor (B) and theirand its corresponding controls.
Supplementary Table 7 from Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
Authors: Ryan Bríd M. , Robles Ana I. , McClary Andrew C. , Haznadar Majda , Bowman Elise D. , Pine Sharon R. , Brown Derek , Khan Mohammed , Shiraishi Kouya , Kohno Takashi , Okayama Hirokazu , Modali Ramakrishna , Yokota Jun , Harris Curtis C.
Published: April 2023

Effect modification between IL-8 and rs1126579.
Supplemental Table 1 and Figure 1 from FOXP3–miR-146–NF-κB Axis and Therapy for Precancerous Lesions in Prostate
Authors: Liu Runhua , Yi Bin , Wei Shi , Yang Wei-Hsiung , Hart Karen M. , Chauhan Priyanka , Zhang Wei , Mao Xicheng , Liu Xiuping , Liu Chang-Gong , Wang Lizhong
Published: April 2023

Supplemental Table 1: Primer sequences used in this study. Supplemental Figure 1: The effect of FOXP3, NF-κB p65-siRNA, and NF-κB inhibitor bortezomib on the growth of DU145 cells.
Supplementary Figure 1 from Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma
Authors: Lin De-Chen , Xu Liang , Chen Ye , Yan Haiyan , Hazawa Masaharu , Doan Ngan , Said Jonathan W. , Ding Ling-Wen , Liu Li-Zhen , Yang Henry , Yu Shizhu , Kahn Michael , Yin Dong , Koeffler H. Phillip
Published: April 2023

Supplementary Figure 1. Prognostic value of PARK2 expression in GBM and ovarian serious cystadenocarcinoma.
Supplementary Materials and Methods and Figure Legends from Epigenetic Silencing of miR-490-3p Reactivates the Chromatin Remodeler SMARCD1 to Promote Helicobacter pylori–Induced Gastric Carcinogenesis
Authors: Shen Jing , Xiao Zhangang , Wu William K.K. , Wang Maggie H. , To Ka F. , Chen Yangchao , Yang Weiqin , Li May S.M. , Shin Vivian Y. , Tong Joanna H. , Kang Wei , Zhang Lin , Li Minxing , Wang Lin , Lu Lan , Chan Ruby L.Y. , Wong Sunny H. , Yu Jun , Chan Matthew T.V. , Chan Francis K.L. , Sung Joseph J.Y. , Cheng Alfred S.L. , Cho Chi H.
Published: April 2023

Supplementary Materials and Methods
Supplementary Tables S1-10 from Reprogramming of the ERRα and ERα Target Gene Landscape Triggers Tamoxifen Resistance in Breast Cancer
Authors: Thewes Verena , Simon Ronald , Schroeter Petra , Schlotter Magdalena , Anzeneder Tobias , Büttner Reinhard , Benes Vladimir , Sauter Guido , Burwinkel Barbara , Nicholson Robert I. , Sinn Hans-Peter , Schneeweiss Andreas , Deuschle Ulrich , Zapatka Marc , Heck Stefanie , Lichter Peter
Published: April 2023

Supplementary Tables S1-10. Supplementary Table S1: Clinico-pathological features of primary treatment-naive and relapsed tamoxifen-resistant breast carcinomas assessed by routine pathological evaluation. Supplementary Table S2: Antibodies for Western blot analyses, ChIP and immunohisto-chemistry. Supplementary Table S3: Primer sequences for qRT-PCR (5'-3'). Supplementary Table S4 : p-values. Supplementary Table S5: Top differentially expressed transcripts between MCF-7 #Wt and #TamR. Supplementary Table S6: ERalpha, ERRalpha and AIB1 target genes identified by ChIP-Seq and gene expression profiling (EP) in MCF-7 #Wt vs. # TamR cells. Supplementary Table S7: ERalpha and ERRalpha target genes identified by ChIP-Seq and gene expression profiling in MCF-7 cells. Supplemetary Table S8: Enrichment of functional categories for ERalpha and ERRalpha target genes in #TamR. Supplementary Table S9: Pairwise relationship between ERRalpha and co-variables in ERalpha-positive breast carcinomas (tumor set III, n=1041). Supplementary Table S10: Effects of co-variables on patient survival in tamoxifen-treated primary breast tumors (GSE9893) stratified to grade and PR status.
Supplementary Figure S7 from The CUL4B/AKT/β-Catenin Axis Restricts the Accumulation of Myeloid-Derived Suppressor Cells to Prohibit the Establishment of a Tumor-Permissive Microenvironment
Authors: Qian Yanyan , Yuan Jupeng , Hu Huili , Yang Qifeng , Li Jisheng , Zhang Shuqian , Jiang Baichun , Shao Changshun , Gong Yaoqin
Published: April 2023

Supplementary Figure S7. CUL4B could directly bind to the promoters of the phosphatase genes and repress their transcription.
Supplementary Figure S3 from eIF4E Threshold Levels Differ in Governing Normal and Neoplastic Expansion of Mammary Stem and Luminal Progenitor Cells
Authors: Avdulov Svetlana , Herrera Jeremy , Smith Karen , Peterson Mark , Gomez-Garcia Jose R. , Beadnell Thomas C. , Schwertfeger Kathryn L. , Benyumov Alexey O. , Manivel J. Carlos , Li Shunan , Bielinsky Anja-Katrin , Yee Douglas , Bitterman Peter B. , Polunovsky Vitaly A.
Published: April 2023

Supplementary Fig. S3. Double K8/Ki-67staining of wild type (WT) and transgenic (WAP-4E) mammary glands (gestation 6).
Supplemental Figure S6 from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
Authors: Crompton Joseph G. , Sukumar Madhusudhanan , Roychoudhuri Rahul , Clever David , Gros Alena , Eil Robert L. , Tran Eric , Hanada Ken-ichi , Yu Zhiya , Palmer Douglas C. , Kerkar Sid P. , Michalek Ryan D. , Upham Trevor , Leonardi Anthony , Acquavella Nicolas , Wang Ena , Marincola Francesco M. , Gattinoni Luca , Muranski Pawel , Sundrud Mark S. , Klebanoff Christopher A. , Rosenberg Steven A. , Fearon Douglas T. , Restifo Nicholas P.
Published: April 2023

Supplemental Figure S6. 8.Akt inhibition of murine CD8+ T cells increased expression of CD62L and CD27, and decreased expression of CD44.
Supplemental Figure Legend from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
Authors: Crompton Joseph G. , Sukumar Madhusudhanan , Roychoudhuri Rahul , Clever David , Gros Alena , Eil Robert L. , Tran Eric , Hanada Ken-ichi , Yu Zhiya , Palmer Douglas C. , Kerkar Sid P. , Michalek Ryan D. , Upham Trevor , Leonardi Anthony , Acquavella Nicolas , Wang Ena , Marincola Francesco M. , Gattinoni Luca , Muranski Pawel , Sundrud Mark S. , Klebanoff Christopher A. , Rosenberg Steven A. , Fearon Douglas T. , Restifo Nicholas P.
Published: April 2023

Supplemental Figure Legend. Legend for Supplemental Figures S1-S7.
Supplementary Figure S3 from UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas
Authors: Wong Stephen Q. , Waldeck Kelly , Vergara Ismael A. , Schröder Jan , Madore Jason , Wilmott James S. , Colebatch Andrew J. , De Paoli-Iseppi Ricardo , Li Jason , Lupat Richard , Semple Timothy , Arnau Gisela Mir , Fellowes Andrew , Leonard J. Helen , Hruby George , Mann Graham J. , Thompson John F. , Cullinane Carleen , Johnston Meredith , Shackleton Mark , Sandhu Shahneen , Bowtell David D.L. , Johnstone Ricky W. , Fox Stephen B. , McArthur Grant A. , Papenfuss Anthony T. , Scolyer Richard A. , Gill Anthony J. , Hicks Rodney J. , Tothill Richard W.
Published: April 2023

CD3+ (Combined TIL grade) between MCV negative (V-MGG) versus MCV-positive (V+MGG) MCCs. n.s., not significant.
Supplementary Figure S5 from Immuno-PET Imaging of Engineered Human T Cells in Tumors
Authors: Mall Sabine , Yusufi Nahid , Wagner Ricarda , Klar Richard , Bianchi Henrique , Steiger Katja , Straub Melanie , Audehm Stefan , Laitinen Iina , Aichler Michaela , Peschel Christian , Ziegler Sibylle , Mustafa Mona , Schwaiger Markus , D'Alessandria Calogero , Krackhardt Angela M.
Published: April 2023

Differential distribution of 89Zr-aTCRmu-F(ab')2 signals within ML2-B7 tumors of mice injected with 2.5D6TCR-transgenic TCM
Supplementary Figure S4 from Immuno-PET Imaging of Engineered Human T Cells in Tumors
Authors: Mall Sabine , Yusufi Nahid , Wagner Ricarda , Klar Richard , Bianchi Henrique , Steiger Katja , Straub Melanie , Audehm Stefan , Laitinen Iina , Aichler Michaela , Peschel Christian , Ziegler Sibylle , Mustafa Mona , Schwaiger Markus , D'Alessandria Calogero , Krackhardt Angela M.
Published: April 2023

Investigation of uptake by biodistribution and autoradiography as well as stability of 89Zr-aTCRmu-F(ab')2 within a clinically relevant ML2-based myeloid sarcoma model of adoptive T-cell transfer
Supplementary Figure 1 from Evaluating Patient-Derived Colorectal Cancer Xenografts as Preclinical Models by Comparison with Patient Clinical Data
Authors: Nunes Manoel , Vrignaud Patricia , Vacher Sophie , Richon Sophie , Lièvre Astrid , Cacheux Wulfran , Weiswald Louis-Bastien , Massonnet Gerald , Chateau-Joubert Sophie , Nicolas André , Dib Colette , Zhang Weidong , Watters James , Bergstrom Donald , Roman-Roman Sergio , Bièche Ivan , Dangles-Marie Virginie
Published: April 2023

Genomic alterations of IGF2-PI3K pathway in MSS human colorectal cancer cell lines. A. Gene expression, gene copy number and mutation data provided by the Cancer Cell Line Encyclopedia were studied in the 36 MSS cell lines out of the cohort of the 62 human colorectal cell lines. Tumors were considered to be amplified if the gene copy number was >3. Gene overexpression is defined by an expression superior to average in all CRC cell line panel + 1 SD. B. Alteration frequencies are expressed as a percentage of the MSS cell lines in green. Data obtained in non-hypermutated patient tumor samples reported by the The Cancer Genome Atlas are noted in red.
Supplementary Table 3 from Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas
Authors: Tang Xiaohu , Wu Jianli , Ding Chien-Kuang , Lu Min , Keenan Melissa M. , Lin Chao-Chieh , Lin Chih-An , Wang Charles C. , George Daniel , Hsu David S. , Chi Jen-Tsan
Published: April 2023

Supplementary Table 3. Differential gene response of RCC4 VHL-deficient and -restored cells upon cystine deprivation
Suppl Table 1 from A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells
Authors: Hölzel Michael , Landsberg Jennifer , Glodde Nicole , Bald Tobias , Rogava Meri , Riesenberg Stefanie , Becker Albert , Jönsson Göran , Tüting Thomas
Published: April 2023

Supplementary Table 1. Results of the gene set enrichment analysis (GSEA) from the comparison of amelanotic MPNST-like versus pigmented mouse melanomas.
Table S3 from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Authors: Henrich Kai-Oliver , Bender Sebastian , Saadati Maral , Dreidax Daniel , Gartlgruber Moritz , Shao Chunxuan , Herrmann Carl , Wiesenfarth Manuel , Parzonka Martha , Wehrmann Lea , Fischer Matthias , Duffy David J. , Bell Emma , Torkov Alica , Schmezer Peter , Plass Christoph , Höfer Thomas , Benner Axel , Pfister Stefan M. , Westermann Frank
Published: April 2023

Neuroblastoma-specific mutations in genes whose hypermethylation and downregulation are associated with high-risk neuroblastoma disease (HyperDownHR)
Supplementary Table S1 from Low Levels of Circulating Adiponectin Are Associated with Multiple Myeloma Risk in Overweight and Obese Individuals
Authors: Hofmann Jonathan N. , Birmann Brenda M. , Teras Lauren R. , Pfeiffer Ruth M. , Wang Ye , Albanes Demetrius , Baris Dalsu , Colditz Graham A. , De Roos Anneclaire J. , Giles Graham G. , Hosgood H. Dean , Lan Qing , Landgren Ola , Liao Linda M. , Rothman Nathaniel , Weinstein Stephanie J. , Pollak Michael N. , Neuhouser Marian L. , Purdue Mark P.
Published: April 2023

Determinants of circulating levels of total adiponectin (µg/mL) among pooled controls.