bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Next Generation Sequencing in Diagnosis and Management of Rare Diseases: Bloom Syndrome
Authors:   “Carol Davila” University of Medicine, Medical Genetics Department, Bucharest, Romania, FOCSA Ina-Ofelia , TUTULAN-CUNITA Andreea ,   Cytogenomic Medical Laboratory, Bucharest, Romania, PAVEL Anca ,   Cytogenomic Medical Laboratory, Bucharest, Romania, PREPELITA Diana ,   Cytogenomic Medical Laboratory, Bucharest, Romania, BRATU Diana ,   Cytogenomic Medical Laboratory, Bucharest, Romania, BOHILTEA Laurentiu Camil ,   “Carol Davila” University of Medicine, Medical Genetics Department, Bucharest, Romania, STAMBOULI Danae ,   Cytogenomic Medical Laboratory, Bucharest, Romania
Published: September 2022

Bloom syndrome is an exceptionally rare autosomal recessive disorder characterized by a considerable genomic instability due to the defective DNA damage repair machine. It is caused by biallelic pathogenic variants in the gene encoding for one of the five human RecQ helicases, RECQL3/BLM. The disorder manifests clinically as growth deficiency, skin anomalies, immunodeficiencies, insulin resistance, and a high predisposition to cancers. Less than 300 patients have been reported so far. In this paper, we report on the first Romanian patient of bi-ethnic origin, molecularly diagnosed with Bloom syndrome. As the most severe complications of the disorder are the malignancies, developing even in childhood, an early diagnosis is essential for further surveillance and therapeutic approach of Bloom patients.
Metaplastic Breast Cancer – a Rare, Aggressive Condition with a Poor Prognosis
Authors:   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, ALBU Andreea Ruxandra , GRADINARU Delia Maria ,   University Emergency Hospital Bucharest, Romania, DUMITRU Adrian ,   University Emergency Hospital Bucharest, Romania, SAJIN Maria ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, IORGA Polixenia ,   University Emergency Hospital Bucharest, Romania, CIRSTOIU Monica Mihaela ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: September 2022

Metaplastic breast cancer (MBC) is a rare, aggressive form of breast cancer first described by pathologists in 2000. It is usually discovered in advanced stages and has a low survival rate. It is divided into various subtypes: low- grade adenosquamous, fibromatosis-like metaplastic, squamous cell, spindle cell, metaplastic with mesenchymal differentiation (including chondroid, osseous, or other types), mixed metaplastic, and myoepithelial carcinomas. Surgery is the treatment of choice, followed by adjuvant chemotherapy and/or radiotherapy. We present the case of a 44-year-old woman with metaplastic breast cancer, reviewing the characteristics of this condition, the particularities of the case, and the treatment chosen in this particular situation.
Faktor – Faktor Yang Mempengaruhi Pembayaran Zakat Pendapatan Di Kota Pekanbaru
Authors: Any Widiyatsari  , Supriani Sidabalok
Published: September 2022

Zakat merupakan salah satu instrumen penting bagi pembangunan kesejahteraan umat. Mengingat bahwa penduduk muslim di Indonesia lebih dari 80% populasi maka potensi zakat adalah sangat besar. Namun realitas pengumpulan zakat masih sangat kecil dibandingkan dengan potensi yang ada. Hal ini juga terjadi di Provinsi Riau dimana realisasi zakat yang terkumpul masih kurang dari 10% potensi yang dimiliki. Dengan demikian penelitian ini bertujuan untuk mengetahui apakah faktor – faktor seperti : (1) religiusitas, (2) pendapatan, dan (3) kepercayaan terhadap lembaga amil zakat (literasi LAZ) berpengaruh terhadap pembayaran zakat/infaq/sedakah (ZIS) di kota Pekanbaru. Penelitian ini melibatkan 100 orang responden yang membayar ZIS melalui lembaga Dompet Dhuafa Pekanbaru pada tahun 2020. Metode penelitian yang digunakan adalah metode analisis kuantitatif berupa teknik statistik dengan alat bantu analis uji statistik non parametrik. Hasil penelitian menunjukkan bahwa hanya faktor pendapatan yang berpengaruh positif signifikan terhadap pembayaran ZIS yaitu sebesar 0,163. Adapun faktor  religiusitas dan literasi LAZ tidak memberikan pengaruh signifikan terhadap pembayaran ZIS di kota Pekanbaru
Faktor-Faktor Yang Mempengaruhi Respon Petani Padi Terhadap Sistem Tanam Jajar Legowo Di Nagari Singkarak Kecamatan X Koto Singkarak
Authors: Yesi Muhariyantika  , Fuad Madarisa  , Erigas Eka Putra
Published: September 2022

The purpose of this research is to 1) AnalyzeThe influence between farmer characteristics and the response of rice farmers to the Jajar Legowo Planting System in X Koto Singkarak District. 2)Analyzingthe effect of the nature of innovation with the response of rice farmers to the Jajar Legowo Planting System in X Koto Singkarak District. 3)Analyzing the influence between the role of extension workers and the response of rice farmers to the Jajar Legowo Planting System in X Koto Singkarak District.The population in this study are farmers who are members of farmer groups who are trying to grow rice using the Jajar Legowo Planting System in Nagari Singkarak District X Koto Singkarak,the population of 9 rice farmer groups is 219 people. The sample was calculated using the Slovins formula with a total of 69 people. The data analysis used in this study is a quantitative descriptive analysis andMultiple linear regression analysis.

Based on the results of the analysis and discussion, some conclusions can be drawn as followsCharacteristic factors of members of the age group and length of farming have a significant effect on the response of rice farmers to the jajar legowo planting system partially, while the characteristics of members of the formal education group, land area and number of family dependents have no significant effect on the response of rice farmers to the jajar legowo planting system in general. partial, the nature of innovation has a significant effect on the response of rice farmers to the jajar legowo planting system partially then the role of extension workers has a significant effect on the response of rice farmers to the jajar legowo planting system partially
Efektivitas Instagram Sebagai Promosi Wirausaha Mahasiswa FIS Universitas Negeri Jakarta Selama Pandemi
Authors: Sary Marisa Puspita , Wijayanti Vera , Putri Maulina Larasati , Bimantoro Anggana Aletta , Firanti Dinda Ayu
Published: September 2022

Eksistensi media sosial di era digital 4.0 memudahkan wirausahawan mempromosikan produk di tengah    keterbatasan akibat pandemi Covid-19. Hal ini mendukung wirausahawan untuk mempromosikan produk secara online.  Penelitian ini bertujuan untuk mengkaji efektivitas penggunaan media sosial sebagai promosi kewirausahaan mahasiswa Fakultas Ilmu Sosial di tengah pandemi. Alasan memilih mahasiswa FIS UNJ karena beberapa mahasiswa membangun wirausaha dengan menjual tipe produk yang lebih bervariasi di tengah pandemi sekaligus sebagai penerapan matakuliah entrepreneur yang terdapat di kurikulum prodi di Fakultas Ilmu Sosial. Penelitian ini mengkaji efektivitas promosi wirausaha yang dilakukan mahasiswa. Penelitian promosi kewirausahaan sebelumnya meneliti wirausahawan sebagai subjek penelitian, sedangkan subjek penelitian ini tertuju pada mahasiswa yang sekaligus berperan sebagai wirausahawan. Metode penelitian menggunakan deskriptif kuantitatif. Data primer didapatkan dengan cara penyebaran kuesioner kepada mahasiswa Fakultas Ilmu Sosial Universitas Negeri Jakarta yang memanfaatkan instagram untuk promosi produk. Data diolah dari kuesioner dan dianalisis menggunakan analisis deskriptif uji t parsial. Hasil penelitian ini dijelaskan dengan model AIDA bahwa promosi produk melalui instagram belum berhasil sesuai yang diharapkan, promosi kurang menimbulkan ketertarikan, dan promosi di instagram tidak sepenuhnya memberikan pengaruh terhadap media promosi produk/jasa. Temuan tersebut terkait dengan tidak terpenuhinya unsur attention pada tahap awal AIDA disebabkan diantaranya konten promosi yang tidak menimbulkan ketertarikan.
Efektivitas Dinas Kependudukan dan Pencatatan Sipil Kabupaten Kuantan Singingi dalam Memberi Pelayanan Publik Pada Masa Pandemi Covid-19
Authors: Febri Dwi Ramayanti  , Febri Yuliani  , Adianto
Published: September 2022

COVID-19 memberi dampak yang sangat besar disemua aspek kehidupan, termasuk pelayanan publik. Untuk membunuh mata rantai penyebaran COVID-19, pemerintah menutup pelayanan publik. Untuk tetap memberi pelayanan publik Dinas Kependudukan dan Pencatatan Sipil Kabupaten Kuantan Singingi menerapkan sistem pelayanan online. Melihat banyaknya keluhan dari masyarakat, setelah dikeluarkanya kebijakan diperbolehkan membuka kembali pelayanan tatap muka, Dinas Kependudukan dan Pencatatan Sipil Kabupaten Kuantan Singingi membuka kembali pelayanan dan dilakukan diluar ruangan kantor untuk menghindari kontak langsung antara pegawai dan masyarakat dan untuk menghindari kerumunan didalam kantor. Tujuan penelitian ini untuk mengetahui dan menganalisa efektivitas dan upaya yang telah dilakaukan oleh Dinas Kependudukan dan Pencatatan Sipil Kabupaten Kuantan Singingi dalam memberi pelayanan pada masa pandemi COVID-19 serta faktor-faktor yang menghambatnya. Penelitian ini merupakan penelitian kualitatif bersifat deskriftif, data penelitian dianalisis dengang  metode analisis data kualitatif. Hasil penelitian menunjukkkan bahwa efektivitas Dinas Kependudukan dan Pencatatan Sipil Kabupaten Kuantan Singingi dalam memberi pelayanan pada masa pendemi COVID-19 masih kurang efektif. Upaya yang telah dilakukan Dinas Kependudukan dan Pencatatan Sipil Kabupaten Kuantan Singingi dalam memberi pelayanan publik pada saat pandemi COVID-19 adalah menerapkan sistem pelayanan online, renovasi ruangan khusus pelayanan, pembuatan situs web atau platform pelayanan online. Faktor-faktor yang menghambat efektivitas Dinas Kependudukan Dan Pencatatan Sipil Kabupaten Kuantan Singingi dalam memberi pelayanan pada masa pendemi COVID-19 adalah disiplin pegawai dan sarana prasaran. Berdasarkan hasil penelitian diperlukan perbaikan sistem pelayanan online, peningkatan disiplin pegawai dan penegasan penerapan protokol kesehatan di Dinas Kependudukan dan Pencatatan Sipil Kabupaten Kuantan Singingi.
Narasi Media Dalam Proses Kebijakan Pengendalian Kebakaran Hutan Dan Lahan Di Kabupaten Bengkalis
Authors: Meirina Suri Dia , Muhammad Faisal Amrillah
Published: September 2022

Tulisan ini bertujuan untuk mempelajari narasi kebijakan yang dikemukakan oleh aktor pada media dalam mempengaruhi proses kebijakan pengendalian kebakaran hutan dan lahan. Kebakaran hutan dan lahan sudah menjadi permasalahan secara global sehingga dibutuhkan kebijakan yang langsung menyentuh permasalahan. Ada banyak aktor dan kelompok kepentingan yang mencoba mempengaruhi pembuatan kebijakan pengendalian kebakaran hutan dan lahan. Tulisan ini merujuk teori Narrative Policy Framework yang menyatakan bahwa narasi berperan dalam proses kebijakan dengan melihat masalah kebijakan, karakter dari aktor, dan solusi kebijakan yang ditawarkan. Data diambil dari media lokal dan nasional yang dapat dipercaya, data yang relevan dengan penelitian kemudian dikumpulkan dengan menggunakan aplikasi Nvivo 12 plus dengan fiture Ncapture. Hasil penelitian menemukan bahwa narasi yang dikemukakan aktor-aktor kebijakan yang menarasikan masalah kebijakan dan solusi kebijakan pada media memberikan pengaruh dalam pembuatan kebijakan pengendalian kebakaran hutan dan lahan.
Implementasi Kebijakan Komunikasi Komisi Penyiaran Indonesia Daerah Riau Dalam Menerapkan Konten Lokal Pada Stasiun Siaran Berjaringan Di Provinsi Riau
Authors: Kenny Anthia  , Suyanto  , Belli Nasution
Published: September 2022

KPI adalah lembaga negara yang independent tentang Penyiaran. KPI terdiri atas KPI Pusat dibentuk di tingkat pusat dan KPI Daerah dibentuk di tingkat provinsi. Dalam menjalankan fungsi, tugas, wewenang, dan kewajibannya, KPI Pusat diawasi oleh Dewan Perwakilan Rakyat (DPR), dan KPI Daerah diawasi oleh DPRD.metode peneletian yan di gunakan kualitatif deskriptif dengan hasil penelitian Dalam penerapan peraturan ini, KPID Riau memang memberikan stimulan seperti penghargaan kepada lembaga penyiaran yang memang menayangakan konten lokal dengan kualitas yang baik, serta durasi yang sesuai

dengan tujuan dari tayangan konten lokal adalah untuk memberikan pemahaman dan mewujudkan rasa kebanggaan serta pengetahuan terhadap daerahnya.
Pernikahan Dini Di Kabupaten Hulu Sungai Utara
Authors: Irza Setiawan
Published: September 2022

Pernikahan Dini di Kabupaten Hulu Sungai Utara meningkat, pada tahun 2018 terdapat 15 kasus, di Tahun 2019 meningkat menjadi 53 kasus, dan di Tahun 2020 semakin meningkat menjadi 168 kasus, Tujuan Penelitian ini adalah untuk menelaah secara kritis bagaimana pernikahan dini di Kabupaten Hulu Sungai Utara serta mendeskripsikan model penanggulangan pernikahan dini di Kabupaten Hulu Sungai Utara, metode menggunakan pendekatan kualitatif dengan tekhnik analisis menggunakan data sekunder berupa literatur buku sehingga dipilihlah teori implementasi dari buku karya Dr. Deborah Stone sebagai pisau analisis teori kemudian dipadukan dengan literature lain seperti buku-buku kebijakan, metodologi, serta jurnal nasional dan jurnal internasional untuk dipadukan dengan data dispensasi kawin yang terjadi di Kabupaten Hulu Sungai Utara, dengan data lapangan reduksi data, penyajian data dan penarikan kesimpulan berdasarkan kesimpulan ditemukan model penanggulangan pernikahan dini yaitu menyamakan persepsi pelaksanan kebijakan tentang apa itu pernikahan dini, berfokus dengan komitmen menunda pernikahan di usia dini dengan meningkatkan kemapanan, perbaikan moralitas masyarakat dan perubahan kultur di masyarakat.
Tradução, adaptação cultural e validação da versão portuguesa do instrumento “knowledge and attitudes survey regarding pain” (kasrp)
Authors: Manuel Batalha Luís , Cristina Ferreira Ana , Leonor Ribeiro Ana , Raposo Carina , Dias Daniela , Santos Juliana , Maria Tarico Bico Correia Isabel , Gomes de Oliveira António , Ângelo Dias de Sousa Teófilo
Published: September 2022

As lacunas na formação dos profissionais de saúde têm sido apontadas como a principal causa de sofrimento inaceitável à luz do conhecimento atual.

O Knowledge and Attitudes Survey Regarding Pain (KASRP) é um instrumento com 41 itens que mede as atitudes dos profissionais de saúde na gestão da dor, sendo útil para diagnosticar necessidades de formação e avaliar a proficiência de ações formativas. O objetivo foi traduzir, adaptar culturalmente e validar uma versão portuguesa do KASRP (KASRP-PT) em Enfermeiros.

Tratou-se de um estudo metodológico desenvolvido em seis fases. A versão portuguesa foi alcançada por consenso em painéis e testada numa amostra de 34 enfermeiros para avaliação da equivalência conceptual, semântica e de conteúdo. A versão resultante foi avaliada em painel através do índice de validade de conteúdo ao nível de item (I-CVI) e de escala (S-CVI). Para a análise métrica recorreu-se ao estudo do índice de dificuldade e de discriminação dos itens, cálculo da consistência interna do instrumento pela fórmula de Kuder-Richardson e estabilidade temporal a 15 dias pelo coeficiente de correlação intraclassse a 95% (ICC 95%).

Para a equivalência conceptual, semântica e de conteúdo houve necessidade de rever alguns itens. O I-CVI variou entre 0,80 e 1,00 sendo o S-CVI médio de 0,98. A versão final do KASRP-PT aplicada em 188 enfermeiros apresentou propriedades métricas sofríveis com baixo índice de dificuldade (0,67) e de discriminação (0,26) dos seus itens, uma homogeneidade questionável (alfa Cronbach 0,627) e moderada estabilidade temporal (ICC 95% 0,552 (0,193-0,744).

O KASRP-PT pode ser um instrumento útil se eliminados alguns itens para melhorar a sua validade e fiabilidade pelo que se recomenda o uso uma versão reduzida a 29 itens.
Hubungan Antara Pembelajaran Andragogi dan Keterampilan Belajar dengan Hasil Belajar Mahasiswa
Authors: Panganton Aldo Regeryo Evans , Reba Yansen Alberth , Udam Mikhael
Published: September 2022

This research aimed to determine the correlation between andragogy learning as well as learning skill and student learning outcome. The present research applied a quantitative research approach with multiple correlational analysis method where the data collection was carried out through questionnaire technique in the form of questionnaires and documentation. The research population involved students from the Guidance and Counseling Program, Faculty of Teacher Training and Education, Cenderawasih University batch 2018, 2019, 2020 and 2021 as many as 101 students. The determination of the sample was performed by total sampling technique in which the researcher used the entire sample with a total of 101 students. The research findings showed a correlation between andragogy learning and learning outcome with a Pearson correlation value of 0.502, a correlation between learning skill and learning outcome with a Pearson correlation value of 0.445 and a correlation between andragogy learning and learning skills and learning outcomes where the correlation coefficient was indicated by an R value of 0.573. Meanwhile, the simultaneous contribution of andragogy learning as well as learning skill and learning outcome was 32.8% (0.328) while the other 67.2% were determined by other variables not examined in this research. The conclusion of this research was that there was a fairly strong correlation between andragogy learning as well as learning skill and student learning outcome.
Profil Permasalahan Umum Siswa Kelas XI dan Implikasinya dalam Program Bimbingan dan Konseling di SMA
Authors: Santoso Santoso , Mataputun Yulius , Wabdaron Densemina Yunita , Sofyan Ahmad
Published: September 2022

The present study aimed: 1) to describe the common problems of female students in grade XI, 2) to describe the common problems of male students in grade XI, 3) to describe the common problems of female and male students in grade XI. The research approach used by the researcher was descriptive type. This study identified common problems experienced by each grade XI student at SMA Negeri 2 Skanto, Keerom Jayapura Regency, Papua. The research sample was a saturated sample (all members of the population) totaling 135 students. Based on research findings on the common problems of female students, there were 55 people (92%) experiencing educational and teaching problems. In the common problem of male students, most or 25 people (58%) experienced personal problems. In the common problems of female and male students, most or 55 people (92%) experienced problems in education and teaching and 25 people (58%) experienced personal problems. It was concluded that a guidance and counseling program for female and male or grade XI Senior High School students is very highly required.
Pengaruh Pendistribusian Zakat Produktif terhadap Tingkat Pengurangan Kemiskinan Mustahik di Kota Banjarmasin
Authors: Rizqa  , Muhammad Yassir Fahmi  , Mochammad Arif Budiman
Published: September 2022

One of the instrument trusted to decrease poverty is zakat especially if distributed to productive activities. This research aimed to find out if the distribution of productive zakat has effect on the decrease level of mustahik poverty, to find out total and classification of mustahik households and the change of mustahik households without and with productive zakat. This research used correlative quantitative method with analysis technique of simple linear regression and CIBEST analysis. This research used saturated sample technique to mustahik of Amil Zakat Board (BAZNAS) of Banjarmasin City with a total of 23 respondents. From the research results, it can be concluded that the distribution of productive zakat has no significant effect decreasing on the poverty level of mustahik. This can be seen from the t count (-1,177) < t table (2,079) and from F count (1,385) < F table (4,30) p value (Sig) in the amount of 0,252 > 0,05 which means that Ho is accepted. Based on total households of mustahik based on CIBEST quadrant before and after the presence of productive zakat fund, there is difference of classification of each mustahik household. The condition change of mustahik household without and with productive zakat fund based on material and absolute poverty index each experienced decrease in the amount of -10,5 and -100%. Spiritual poverty index does not change at all either before or after accepting productive zakat in the amount of zero percent. While prosperity index increase to 504,7%.
Pengaruh Kualitas Produk, Kualitas Pelayanan dan Promosi terhadap Kepercayaan Pelanggan (Konsumen) di Erha Skin Padang
Authors: Irdha Yusra  , Widia Wati Rizki
Published: September 2022

Companies engaged in the service sector must be able to maintain a good reputation in the eyes of their customers. However, there are still many complaints that are felt by customers. This study aims to determine Product Quality, Tangibles, Reliability, Responsiveness, Assurance, Emphaty, Promotion and Customer Trust in Erha Skin Padang. The samples were determined by using the Stratified Random Sampling technique with a total of 56 customers (consumers). Data were collected through questionnaires and then analyzed statistically descriptive and Independent-Sample T-Test with the SPSS version 16 program. The results of the data analysis show that Product Quality, Tangibles, Reliability, Responsiveness and Emphasis are the main factors that determine the level of customer trust. Meanwhile, Assurance and Promotion have a less dominant contribution to customer trust
Pengaruh Hasil Belajar Matematika terhadap Hasil Belajar Akuntansi pada Mahasiswa Jurusan Akuntansi Politeknik Negeri Banjarmasin.
Authors: Priyougie Priyougie , Ahsanul Haq  , Linda Permanasari
Published: September 2022

There are several similarities between mathematics and accounting, which both emphasize the use of logic, use symbols, and have definite formulas. In general, if a student has good math skills, chances are that his accounting skills are also good. Therefore, the researcher wanted to know whether there was an effect of mathematics learning outcomes on accounting learning outcomes for students of the Accounting Department at the Banjarmasin State Polytechnic. For testing the hypothesis, the researchers took the final grade data for mathematics courses in the first semester and the average final grade data from several accounting-based courses in the following semesters such as Intermediate Financial Accounting, Cost Accounting, Accounting Information Systems, Public Sector Accounting. , and Introduction to Accounting Practices. After the data is tested for normality, a correlation coefficient test, a coefficient of determination test, and a simple linear regression test were conducted. The test results indicate that there is a strong influence between the learning outcomes of mathematics courses on the learning outcomes of several accounting courses for students of the Accounting Department of the Banjarmasin State Polytechnic. The average learning outcomes of several accounting courses are influenced by 47.66% by learning outcomes of mathematics courses while the remaining 52.34% is influenced by other variables.
PENGARUH PEMBIAYAAN MURABAHAH, MUDHARABAH, MUSYARAKAH DAN ISTISHNAâ€™ TERHADAP TINGKAT PROFITABILITAS BANK UMUM SYARIAH DI INDONESIA
Authors: Andriani Andriani , Bahit Maida Sari
Published: September 2022

Penelitian ini bertujuan untuk mengetahui pengaruh pembiayaan murabahah, mudharabah, musyarakah dan istishnaâ€™ terhadap tingkat profitabilitas (ROA) pada bank Umum Syariah (BUS) di Indonesia. Hasil penelitian menunjukan nilai R2 kurang dari 50% menunjukan bahwa model penelitian ini belum cukup representatif untuk menjelaskan variabel yang mempengaruhi ROA pada BUS . Hal ini sejalan dengan penelitian sebelumnya yang menggunakan variabel dependen dan independen serupa. Pembiayaan murabahah, mudharabah, musyarakah dan istihishnaâ€™ secara simultan berpengaruh signifikan terhadap tingkat profitabilitas BUS. Secara parsial pembiayaan mudharabah berpengaruh signifikan dan positif dan pembiayaan musyarakah berpengaruh signifikan negatif terhadap profitabilitas BUS. Selanjutnya pembiayaan isthishnaâ€™ dan pembiayaan murabahah tidak berpengaruh signifikan terhadap profitabilitas BUS.
Penggunaan Aplikasi Zahir Accounting untuk Penyusunan Laporan Keuangan pada CV Wira Bone
Authors: Raudatul Janah  , Yuli Fitriani  , Karolina
Published: September 2022

Financial statements are usually prepared by the company for activities that have occurred for transactions. Likewise, CV Wira Bone, which is a CV or a company engaged in a welding workshop. Previously, this CV did not have financial statements, only simple evidence of transactions and financial records. So, in knowing the benefits, mistakes can still occur and making decisions will be difficult because you do not know the company's financial performance. So in this case it is necessary to prepare financial reports to provide information about the company's financial records. The compilation of financial reports can be done using a computerized system using the Zahir Accounting Version 6. The data obtained is in the form of financial data that is owned by the company which is requested directly and its suitability with the company's activities that have occurred. With the Zahir application, the resulting financial reports are more accurate, effective and efficient so that they can find out the company's financial performance for making future decisions. The use of Zahir Accounting Version 6 is a good solution for solving problems that occur regarding company finances because it can provide convenience for the company itself. So using this computerized system will be better than using a manual system because it can provide convenience, the results obtained are accurate, effective, efficient and can minimize the time used
Pendekatan Maqasid Syariah dan Peran Keuangan Syariah untuk Mitigasi Dampak Ekonomi Pandemi Covid-19
Authors: Mochammad Arif Budiman
Published: September 2022

Pandemi Covid-19 memberikan dampak yang serius dan luas terhadap perekonomian semua negara di dunia. Dalam hal ini, pemerintah dituntut memberikan respons secara tepat dan mengeksekusi berbagai langkah penanganan secara cepat untuk memitigasi berbagai dampak ekonomi tersebut sehingga ketahanan ekonomi dan kelangsungan kehidupan segenap warga di tengah situasi pandemi tetap dapat diselamatkan. Maqasid Syariah yang menekankan terpeliharanya keselamatan agama, akal, jiwa, keturunan, dan harta dapat digunakan sebagai strategi pendekatan dalam mengatasi pandemi Covid-19. Keuangan syariah dengan berbagai instrumennya juga dapat dioptimalkan sebagai alternatif untuk memitigasi dampak ekonomi akibat pandemi
PENGARUH MANAJEMEN LABA, RASIO KEUANGAN TERHADAP PERINGKAT OBLIGASI
Authors: Petty Arisanti  , Eko Prasetyo  , Rini Ratna Nafitasari
Published: September 2022

Investasi digolongkan menjadi dua jenis, yaitu investasi dalam surat kepemilikan (saham) dan investasi dalam surat utang (obligasi). Bursa Efek Indonesia mendefinisikan obligasi sebagai surat utang jangka menengah-panjang yang dapat dipindahtangankan yang berisi janji dari pihak yang menerbitkan untuk membayar imbalan berupa bunga pada periode tertentu dan melunasi pokok utang pada waktu yang telah ditentukan kepada pihak pembeli obligasi tersebut. Jenis data yang digunakan dalam penelitian ini adalah data sekunder berupa laporan keuangan tahunan yang terdaftar di Bursa Efek Indonesia (BEI).

Jenis data yang digunakan dalam penelitian ini adalah data sekunder berupa laporan keuangan tahunan yang terdaftar di Bursa Efek Indonesia (BEI). Hasil dari penelitian 1. Manajemen laba yang berpengaruh terhadap peringkat obligasi. 2. Rasio likuiditas berpengaruh terhadap peringkat obligasi. 3. Rasio aktivitas tidak berpengaruh terhadap peringkat obligasi.
Cash Expenditure Accounting Information System Operational Cost Driver At the Fleet Department of PT Cipta Krida Bahari Banjarmasin
Authors: Isnawati  , Hikmahwati  , Nailiya Nikmah
Published: September 2022

This study is to describe the accounting information system for operating cash disbursements of drivers at the Fleet department of PT Cipta Krida Bahari Banjarmasin. The aim is to find out the procedures in the driver operating cost expenditure system. This study uses qualitative research in the form of a brief history of the company, organizational structure, duties, responsibilities, records, and documents used, as well as the operating cost driver expenditure system procedures at the flee department of PT Cipta Krida Bahari Banjarmasin. The research approach uses a descriptive approach related to the accounting information system for operating cash disbursements of drivers at the fleet department of PT Cipta Krida Bahari Banjarmasin. The results of the study can be concluded that the accounting information system for cash disbursements for operating costs of drivers in the fleet  department of PT Cipta Krida Bahari Banjarmasin has related functions, namely the commercial sales function, operation function, driver function, fleet  admin function, fleet  leader function, manager function, and finance function. The procedure for disbursing cash for driver operational costs is the procedure for ordering goods by the customer, the procedure for submitting money for travel, procedures for disbursing/transferring money for travel, and the procedure for recording money for travel. Documents used in the cash disbursement system for a driver’s operating costs are travel documents, PUO, DA, manifest, SIJK, BBM notes, manifest, and TCA. The records used are the FAST system, Cash Advance application, TCA website, MCM system, Middleware system, Ramco system, and enterprise system
Analisis Kebutuhan Pembangunan Fasilitas Pada Bidang Kesehatan di Provinsi Kalimantan Selatan Menggunakan Waqaf dengan Metode ANP
Authors: Muhammad Yassir Fahmi  , Mutiara Sadewa Manik
Published: September 2022

Untuk menentukan penggunaan harta waqaf, nazhir atau lembaga waqaf perlu melakukan analisis kebutuhan sehingga harta waqaf benar-benar bermamfaat bagi masyarakat (mauquf alaih). Pembangunan di bidang kesehatan merupakan salah satu penggunaan harta waqaf. Penelitian ini bertujuan untuk menemukan prioritas kebutuhan pembangunan fasilitas pada bidang kesehatan di Provinsi Kalimantan Selatan menggunakan harta waqaf dengan metode ANP (Analitic Network Process) berdasarkan pendapat nazhir, waqif,pemerintah dan akademisi.  Berdasarkan hasil penelitian dapat disimpulkan bahwa pembangunan fasilitas layanan kesehatan merupakan kebutuhan proritas di Provinsi Kalimantan Selatan dalam upaya meningkatkan kualitas kesehatan masyarakat. Sedangkan klinik merupakan kriteria yang paling utama dalam pembangunan fasilitas layanan kesehatan di provinsi ini menggunakan harta waqaf
The Effect of Regional Income and Financing on Regency/City Capital Expenditures in South Sumatera Province
Authors: Angreini Fitri , Kartika Rachma Sari  , Dwitayanti Yevi
Published: September 2022

Penelitian ini bertujuan untuk menganalisis pengaruh pendapatan daerah dan pembiayaan terhadap belanja modal Kabupaten/Kota di Provinsi Sumatera Selatan pada tahun 2018 sampai dengan 2020. Peneliti menggunakan data sekunder yang bersumber dari situs resmi Direktorat Jendral Perimbangan Keuangan (DJPK) serta situs resmi Badan Pemeriksaan Keuangan Perwakilan Provinsi Sumatera Selatan. Jumlah sampel yang diambil pada penelitian ini adalah sebanyak 30. Sampel diambil menggunakan Teknik purposive sampling. Data penelitian diolah menggunakan statistik deskriptif dan analisis regresi linear berganda melalui bantuan aplikasi Statistical Product and Service Solutions (SPSS). Berdasarkan hasil penelitian yang dilakukan menunjukkan bahwa secara parsial Pendapatan Asli Daerah (PAD) memiliki pengaruh terhadap Belanja Modal, Pendapatan Transfer berpengaruh terhadap Belanja Modal, Lain-Lain Pendapatan Daerah yang Sah tidak berpengaruh secara signifikan terhadap Belanja Modal, Penerimaan Pembiayaan tidak berpengaruh secara signifikan terhadap Belanja Modal, dan Pengeluaran Pembiayaan tidak memiliki pengaruh terhadap Belanja Modal. Sedangkan secara simultan Pendapatan Asli Daerah (PAD), Pendapatan Transfer, Lain-Lain Pendapatan Daerah yang Sah, Penerimaan Pembiayaan, dan Pengeluaran Pembiayaan memberikan pengaruh positif dan signifikan terhadap Belanja Modal.

Kata Kunci: Pendapatan Daerah, Belanja Modal, Pembiayaan.
The Impact of Living Arrangement to Elderly Nutritional Health Status in Jember
Authors: Dewi Sofia Rhosma
Published: September 2022

Introductions: Nutrition has an important role in maintaining the elderly’s health status. The living arrangement is one of the external factors affecting access to food. This study aims to determine the impact of living arrangements on the nutritional status of the elderly. Method: It is a correlational study with a cross-sectional approach. A total of 103 elderly were involved through a consecutive sampling technique. A questionnaire and MNA were used to collect the data, and a chi-square test was used to answer the hypothesis. Result: Statistical analysis results p-value of 0.000 smaller than α 0,05 with RR 11,458 95% confidence interval. Analysis: This means that the living arrangement impacts the elderly nutritional status, and the elderly who live alone are at 11,458 greater risks of experiencing malnutrition than the elderly who live with their families. Discussion: Being engaged with the family provides social support for them. Social interaction needs to be improved so that the elderly will create a positive coping mechanism, enjoy the taste of the food, and have a better quality of life.
Analisis Hubungan Gambaran Diri terhadap Kualitas Hidup Penderita Kusta
Authors: Toru Veronika
Published: September 2022

Introductions: Data from the Nggaha Ori Angu health center in 2015 there were PB (Pausi Basiler) 5 people, while MB (Multi Basiler) 4 people, in 2016 patients with PB 6 people while MB 5 people in 2017 with PB 7 people, MB 5 people. Leprosy if handled carefully can cause several problems for people with leprosy such as problems faced, especially in the eyes, hands and feet (2012). The aim this tudy to analyze the self-concept of the quality of life of people with leprosy in the working area of the Nggoa Health Center, East Sumba Regency. Methods: This study used an analytic study with a cross sectional design. Held in July 2019 in the Nggoa Health Center Work Area, East Sumba Regency. The sample size is 34 people with total sampling technique. Result: The average self-concept andquality of life of leprosy patients is not good. There is a relationship between self-image (p 0.022), and the quality of life of people with leprosy at the Nggoa Health Center, East Sumba Regency. Conclusion: That most people with leprosy have a poor self-image, and self-image with the quality of life of leprosy patients is very closely related. To the family as the most important person to provide more intensive support, and the health center to be actively involved in services for leprosy patients to provide promotive and curative actions for leprosy sufferers.
keywords: Leprosy patients; quality of life; self image
Gambaran Perilaku Altruistik dan Empati Mahasiswa Keperawatan Dalam Pembelajaran Daring Di Era Pandemi Covid-19
Authors: Leokuna Irwan Adiputra , Tambunan Evelyn Hemme
Published: September 2022

Abstrak: Perilaku altruistik dan empati merupakan perilaku prososial yang harus dimiliki oleh perawat profesional. Pengembangan perilaku ini dimulai dari tahap pendidikan keperawatan, walaupun proses pembelajaran dilaksanakan secara daring di era pandemi Covid-19. Tujuan penelitian ini adalah untuk mengetahui gambaran perilaku altruistik dan empati mahasiswa keperawatan program sarjana keperawatan pada era pembelajaran daring di salah satu Universitas swasta di Bandung. Metode: deskriptif kuantitatif dengan metode sampling simple random sampling. Sample penelitian adalah mahasiswa program studi sarjana keperawatan Fakultas Ilmu Keperawatan di salah satu Universitas swasta di Bandung. Jumlah sampel adalah 118 dan waktu penelitian adalah bulan Juni-Desember 2021. Instrumen penelitian yang digunakan adalah kuesioner yang telah valid yaitu kuesioner perilaku altruisitk dan empati. Data kuesioner dikumpulkan menggunakan google form dan data dianalisa menggunakan distribusi frekuensi untuk mengetahui perilaku altruistik dan empati dalam kategori positif dan negatif. Hasil: 62 responden (53%) berperilaku altruistik negatif dan 60 responden (51%) berperilaku empati negatif. Sedangkan 56 responden (47%) berperilaku altruistik positif dan 58 responden (49%) berperilaku empati positif. Kesimpulan dan saran: Sebagian besar dari responden berperilaku altruistik dan empati negatif, dan sebagian kecil berperilaku altruistik dan empati positif. Diharapkan tenaga pendidik dapat meningkatkan pengembangan perilaku altruistik dan empati dalam pembelajaran daring.

Kata Kunci : Perilaku altruistik dan empati; Mahasiswa keperawatan; Pembelajaran daring
Time – Timing – Out of Time? Auswirkungen temporaler Herausforderungen auf die sozialen Beziehungen unterstützt kommunizierender Jugendlicher
Authors: Niediek Imke
Published: September 2022

In dem Beitrag stehen die Lebenswelten von Jugendlichen mit komplexen Unterstützungsbedarfen im Zentrum, die aufgrund körperlich-motorischer und/oder kognitiver Beeinträchtigungen in ihrem Alltag alternative und ergänzende Kommunikationsformen verwenden. Ausgehend von temporalen Besonderheiten der Gesprächsorganisation, die mit diesen Kommunikationsformen einhergehen, werden die Folgen für die sozialen Beziehungen der Jugendlichen mit Peers und Freunden beleuchtet. Eine verbal-sprachlich organisierte Welt, so zeigt der Blick in den internationalen Forschungsstand, ruft zeitliche Ordnungen hervor, welche die Jugendlichen vor Dilemmata der Selbstwahrnehmung und Selbstdarstellung, wie auch der Wahrnehmung durch andere stellt. Diese Ordnungen können auch in digitalen Räumen nur teilweise aufgelöst werden, wie Befunde aus einem Begleitforschungsprojekt mit unterstützt kommunizierenden Jugendlichen zeigen. Der Beitrag schließt mit inhaltlichen und methodischen Überlegungen für weitere Forschung.
The effect of duct width and pancreatic gland structure on pancreatic fistula rates in patients who underwent pancreaticoduodenectomy for pancreatic cancer
Authors: ALKURT Ertugrul Gazi , DURAK Doğukan , TUTAN Mehmet Berksun , ŞAHİN Fatih , ŞAHİNER İbrahim Tayfun
Published: September 2022

Introduction: One of the most important causes of morbidity in pancreaticoduodenectomy (PD) surgery is pancreatic anastomosis leakage. There is a possibility of pancreatic fistula even in the most experienced hands. After PD, pancreatic fistula occurs between 10% and 20% in various series. This study aims to evaluate the effects of pancreatic duct size and pancreatic tissue on the development of pancreatic fistula after PD is performed in our center.
Material and Method: Pancreatic duct size was categorized as small <3 mm and large >3 mm. Pancreatic gland tissue was categorized as a soft, medium, and hard. These variables were calculated preoperatively with the help of computed tomography (CT), ultrasonography(USG), and Endoscopic ultrasound (EUS), and postoperative pathology results. It was accepted that the 24-hour flow rate of the drain behind the pancreatic anastomosis was more than 50 ml during 3 days after PD and/or the amylase concentration of the drain content measured at 3 different times was 3 times higher than the serum amylase concentration.
Results: A total of 90 patients were included in the study, anastomotic leakage was not observed in 63 (70%) of 90 patients, and leakage was observed in 27 (30%) patients. The mean age was 71.22±10.78 years (p=0.615). There was no statistically significant difference between the ductus diameters between the two groups (p=0.240). There was no statistical difference between the groups formed according to pancreatic duct width. (p=0.059). It was observed that 60.3% of the patients in the non-leakage group had a hard appearance, and this rate was statistically significantly reduced to 29.6% in the patients with leakage (p=0.008).
Conclusion: In summary, our study showed that pancreatic fistula after PD is associated with soft pancreatic parenchyma. The surgeon should consider this risk factor when performing a PD and be more careful to reduce the rate of pancreatic fistula.
Association of COVID-19 vaccine with lymph node reactivity: an ultrasound-based study
Authors: ÇEVİK Belma
Published: September 2022

Aim: Millions of people worldwide have been infected and died due to the pandemic caused by COVID-19. Vaccination is the most effective way to deal with the pandemic. Though vaccines are safe, they are not completely risk-free, and some side effects can occur after vaccination such as lymphadenopathy. This study, it was aimed to measure the lymph node reactivity that may develop after mRNA vaccination.
Material and Method: A total of 50 healthy people were included in the study. Left axillary and supraclavicular ultrasound examinations were performed before and one week after the administration of the mRNA vaccine. Each patient was assessed for supraclavicular and level 1 axillary lymph region in terms of the presence, size (long and short axis), and cortex thickness of the lymph nodes.
Results: Of the patients participating in the study, 23 (46 %) were male, 27 (54 %) were female, and the median age was 33. In comparison, the difference in long, short axis and cortex diameter measurements of the supraclavicular lymph node before and after vaccination was found to be statistically significant (p=0.034, 0.021, 0.004, respectively). Similarly, the difference in the long, short axis, and cortex thickness of the left axillary lymph node before and after vaccination was statistically significant (p<0.001, <0.001, <0.001, respectively).
Conclusion: Anti-Covid-19 vaccines may cause lymphadenopathy as a result of reactivation in lymph nodes in the left axillary and supraclavicular regions. When lymphadenopathy is detected in these regions, the vaccine should be questioned in the clinical history and ultrasound follow-up should be performed on the patient.
The effect of serum 25-hydroxy vitamin D levels on malignancy in exophytic thyroid nodules
Authors: ARSLAN İsmail Emre , HEPŞEN Sema , AKHANLI Pınar , UCAN Bekir , ÖZTÜRK ÜNSAL İlknur , ÇALAPKULU Murat , ÇAKAL Erman
Published: September 2022

Aim: The increase in the incidence of thyroid cancer brings about research of new risk factors. In this study, we aimed to investigate the effect of vitamin D status on malignancy in exophytic nodules.
Material and Method: Two hundred and sixteen patients with exophytic thyroid nodules were included in the study. All patients’ thyroid nodule ultrasonographic features, fine needle aspiration biopsy cytology results, rate of surgery and surgery histopathological results were recorded. Vitamin D levels were analyzed and patients were divided into two groups as vitamin D sufficient groups (vitamin D≥20 ng/ml) and vitamin D deficient group (vitamin D<20 ng/ml).
Results: Malignancy rate was significantly higher in the vitamin D deficient group (%19 vs %8.7; p=0.03). There were no significant difference between two groups in terms of demographic characteristics and ultrasonographic features including diameter, hypoechoic nature, having irregular border and microcalcifications.
Conclusion: In exophytic nodules, vitamin D deficiency increases malignancy risk. Determining vitamin D levels may be useful in patients with exophytic nodules.
Results of Y-stent-assisted-coiling with a low-profile Neuroform Atlas stent in complex bifurcation aneurysms
Authors: SAYIN Bige , DAĞLIOĞLU Ergün
Published: September 2022

Aim: Neuroform Atlas is a low-profile stent with an open-cell structure that can be deployed via a low-profile microcatheter. This study analyzed the safety, durability, and efficiency of Y-stent-assisted coiling (Y-SAC) with two Neuroform Atlas stents for treating unruptured wide-neck complex bifurcation aneurysms.

Material and method: We retrospectively reviewed patients who were treated for intracranial bifurcation aneurysms using the Y-SAC technique with two Neuroform Atlas stents. A total of 94 consecutive patients were included in the study. Clinical and angiographic results and complications were evaluated before and after the procedure.

Results: Y-SAC was successfully performed (100%) without any technical complications in any case. The mean angiographic follow-up period was 14.6±6.6 months. Follow-up DSA was performed on 93.6% of patients. The last follow-up angiograms demonstrated complete occlusion (RROC I) in 92%, and near-complete occlusion (RROC II) in 7% of the aneurysms. There was no mortality in this study. A procedure-related complication occurred in 4.2% of patients and caused permanent morbidity in 1% of patients.

Conclusion: In the endovascular treatment of wide-neck complex bifurcation aneurysms, the Y-SAC method with two Neuroform Atlas stents is safe and effective with high aneurysm occlusion rates and a low risk of procedural complications.
Prognostic importance of thrombospondin-1, VEGF, PDGFR- β in diffuse large B-cell lymphoma
Authors: BATMAN Adnan , CİFTCİLER Rafiye , ATEŞOĞLU Elif Birtaş , HACIHANEFİOĞLU Abdullah
Published: September 2022

Aim: In this study, we aimed to investigate the relationship between the staining rates of thrombospondin-1, VEGF, and PDGFR-in tissue preparations in patients diagnosed with DLBCL and their clinical features at the time of diagnosis, and response to treatment and prognosis.

Material and Method: A total of 44 patients with a diagnosis of DLBCL and 13 patients diagnosed with control reactive lymphadenopathy were included in this study. After immunohistochemical staining of the pathology preparations of the patient and control groups with VEGF, PDGFR-β and thrombospondin-1 stains, the clinical characteristics of the patients and the relationship between survival analysis and staining rates were statistically analyzed.

Results: When the patients were compared with the control group in terms of VEGF, PDGFR-β, and thrombospondin-1 staining rates, we found that staining with PDGFR-β was lower in patients (p=0.009). Although it was not statistically significant for PDGFR-β, it was observed that 5-year OS and PFS values were low in patients with high levels of expression, on the contrary, 5-year OS was low in patients with high thrombospondin staining rate. A negative correlation was observed between thrombospondin-1 and PDGFR-β (p=0.003, r=-0.440).

Conclusion: As a result, although no relationship was found between VEGF and survival in our study, it was observed that PDGFR-β and thrombospondin-1 were effective in prognosis. A negative correlation was observed between thrombospondin-1 and PDGFR-β.