bluuebunny/crossref_metadata_2025 huggingface dataset:
Diş Hekimliği Eğitiminde Beceri ve Yeterliğin Değerlendirilmesi I: Kontrol Listeleri ve Ölçekler
Authors: AKALTAN Kadriye Funda
Published: November 2019

Diş hekimliği
eğitiminin hedefi; mezunların güvenli, etkili ve bağımsız uygulamaları
yapabilme seviyesine ulaşmalarına yardımcı olmaktır. Bu düzeydeki yeterlik;
mezuniyet için gerekli minimum performans seviyesindeki akademik bilgi, klinik
beceri ve profesyonel davranışların kazanımını gerektirir. Diş hekimliği
eğitimindeki beceri kavramı; mesleki becerileri akla getirir. Bununla birlikte,
diş hekimliği gibi meslekler için öğrencilerin sadece klinik olarak yetkin olmakla
kalmayıp, topluma iyi hizmet verebilmek için iyi uyum becerilerine de sahip
olmaları beklenir. Performans kontrol listeleri ve ölçekler öğrencilerin
becerilerinin ölçülmesinde kullanılan araçlardır. Çok iyi bilindiği gibi,
“değerlendirme öğrenimi yönlendirir” ve öğrenimin şeklini ve içeriğini
programlar. Bu derleme çalışmasında, ölçme ve değerlendirme yöntemleri; kontrol
listeleri ve ölçeklerin hazırlığı, kullanımı ve doğru ölçme aracının tercihi
konusunda bilgi verilerek, diş hekimliği öğrencilerinin yeterlik ve
becerilerinin ölçülmesinde kullanılan güncel uygulamalar konusunda farkındalık
oluşturulmaktadır.
Diş Hekimliği Eğitiminde Beceri Kavramı: 21. Yüzyıl Becerileri
Authors: Akaltan Kadriye Funda
Published: November 2019

Amaç: 

Diş
hekimliğinde beceri kavramı; akla mesleki becerileri getirir. Oysa ki; mezun
diş hekimlerinin sadece klinik beceri kazanmakla kalmayıp, topluma iyi hizmet
sunabilmek için - iletişim, düşünme ve problem çözme, takım çalışması gücü,
hayat boyu öğrenme ve bilgi yönetimi, girişimcilik, etik, ahlak ve
profesyonellik ve liderlik gibi -  21.
yüzyıl becerilerine sahip olmaları da gerekir. Hekimlerin etkili uyum
becerisine sahip olması durumunda, hasta memnuniyetinin ve tedaviden sağlanan
faydanın arttığı; hasta anksiyetesinin ve hasta şikayetlerinin azaldığı
bilinmektedir. Diş hekimlerinin tedavi uygulamalarında güncel bilgi ve
becerileri yakalamaları, zor tedavi planlamalarını başedebilmeleri, çalışma
ortamlarındaki işbirlikçi çalışmaya uyum sağlamaları açısından da uyum
becerilerinin önemi büyüktür. Yetkin mezunların yetiştirilmesi için
fakültelerin müfredatlarında uyum becerisi eğitimine de yer vermeleri beklenir.
Anahtar kelimeler: diş hekimliği eğitimi, beceri eğitimi, 21. yüzyıl
becerileri.
Seed saving in Atlantic Canada: Sustainable food through sharing and education
Authors: Worden-Rogers Norma Jean , Glasgow Kathleen , Knezevic Irena , Hughes Stephanie
Published: November 2019

Seed saving is an important element of seed security. Seed saving can support biodiversity, nourish food systems, facilitate environmental education, and enable the creation of networks that support food sovereignty. Public interest in seed security is on the rise, but local resources and funding to support seed activities is limited. The survival of seed collections, libraries, banks, and farms depends on personal relationships within the seed community. While Atlantic Canada’s seed saving community is scattered geographically, it is tightly knit. Seed savers share knowledge, information, and tools, sometimes between competitor businesses. At times, information is shared between those with commercial interests, such as seed companies, and public events such as seed swaps, as individual success is contingent on the overall health of the seed system. In this field report, we synthesize findings from three case studies on seed saving in Atlantic Canada, which map regional seed activities, and detail the opportunities and challenges that such initiatives face. While Atlantic Canada has seen growth in the number and scale of both public and private seed saving initiatives, much work remains to be done. Nevertheless, the initiatives constitute a critical mass that can benefit from this assessment upon which future actions can be based.
Uncovering hidden urban bounty: A case study of Hidden Harvest
Authors: DesRivières Chloé Poitevin
Published: November 2019

Urban food systems primarily rely on foods grown in rural spaces, and often face challenges in creating spaces to grow fresh, healthful and affordable food in cities. Urban food harvest organizations aim to overcome these challenges by locating and harvesting food that already exists in cities on the numerous fruit- and nut-bearing trees located on public and private lands. Hidden Harvest is a leading initiative for urban fruit and nut harvesting in Canada, and unique in its for-profit social enterprise model. The organization aims to legitimize and support the practice of harvesting fruits and nuts in urban areas, and provides a means to increase access to—and availability of—fresh, healthful foods hyper-locally in Ottawa, as people harvest from their own (or nearby) neighborhoods. This field report examines the challenges and opportunities faced by Hidden Harvest in attempting to link multiple social, environmental and economic goals relating to food sovereignty, social justice and ecological sustainability. In particular, the organization seeks to establish a self-sustaining business model through innovative solutions and the development of networks with local food processes, food organizations and businesses, which enables Hidden Harvest to grow and develop distinct ties and relationships in Ottawa. This case study reveals how organizations such as Hidden Harvest use food to enhance and tie together local economies, knowledge, food security and community well-being.
Depressão pós-parto e variáveis sociodemográficas em mães de bebês com e sem Síndrome de Down
Authors: Ferreira Tahena Silva , De Campos Bárbara Camila , Rodrigues Olga Maria Piazentin Rolim
Published: November 2019

A depressão que se inicia no puerpério é denominada como depressão pós-parto materna (DPP-M). A Síndrome de Down (SD) é uma cromossomopatia de alta incidência que ocasiona manifestações físicas, clínicas e intelectuais específicas. Objetivou-se descrever e comparar a frequência da DPP-M e de características sociodemográficas em mães de bebês com e sem SD e identificar possíveis preditores da DPP-M entre as variáveis sociodemográficas maternas, do bebê e familiares. Participaram 60 díades. Utilizou-se um questionário sociodemográfico e a Edinburgh Postpartum Depression Scale (EPDS). Os resultados não indicaram diferença significativa nos índices de DPP-M dos grupos, sendo esses mais elevados em mães de bebês sem SD. Comparando as variáveis sociodemográficas, o número de filhos e a idade do bebê foram maiores entre mães de bebês com SD e mais mães de bebês sem SD trabalham fora. A escolaridade, o tipo de família e a idade do bebê foram preditores para DPP-M.
Las anécdotas de un “paria con voz”: el hombre gay en una selección de relatos de Cartas a hombres (2018), de David Ulloa
Authors: Rojas González José Pablo
Published: November 2019

El presente ensayo analiza, en tres relatos de David Ulloa, la construcción de la subjetividad gay como una subjetividad con contradicciones (producto de su situación en el mundo), que se mueve entre la asimilación y la rebeldía. Primero, el estudio considera la noción de “paria”, explicada por Eleni Varikas, pero también por Hannah Arendt y Didier Eribon, con el fin de plantear al homosexual como un “paria moderno”. Luego, se ofrece un análisis de los relatos, con el que se explica cómo la voz del narrador-protagonista es una voz propia (en tanto expone diferentes momentos de su vida). Aunque con contradicciones, esta voz trata de alzarse en contra de los imperativos constituidos en torno a aquellos sujetos que son despojados sistemáticamente –porque no pueden “hablar”– de las condiciones que posibilitan una vida política, social y privada plena. En el trabajo, se hace referencia a distintos elementos tratados a lo largo de los textos de Ulloa, como la sexualidad, las emociones, la identidad o la enfermedad (el VIH/sida).
Model of impact of household assets on labor price: European experience
Authors: Petkova Lesia , Zagoruiko Ivan , Palamarchuk Dmytro
Published: November 2019

This article deals with existing models of household behavior, based on the assumption of the possibility of employees to determine their own level of consumption and employment, depending on a given wage rate and accumulated assets. An alternative view is offered that the wage rate accepted by employees can be expressed through financial assets and employment. Based on this assumption, the model "financial assets – labor price" was developed, determining the impact of the volume of financial assets of households and the level of employment on the wage rate, the minimum acceptable for workers.

The model was tested in twelve European countries. The calculations confirmed the basic hypothesis of the study, namely the dependence of the level of wages on the volume of available assets and employment.
Antioxidant, Antibacterial Activity and GC-MS Analysis of Extract of Giant Forest Ant Dinomyrmex gigas (Latreille, 1802)
Authors: Evana Evana - , Pratiwi Pratiwi , Fathoni Ahmad , Efendi Oscar , Agusta Andria
Published: November 2019

Giant forest ant Dinomyrmex gigas is one of the largest ants species in the world, native to the rain forests of Southeast Asia. It is known that ants have glands that produce chemical compounds that inhibit the growth of microbes. Therefore, it is necessary to deter-mine the antioxidant and antibacterial activities as well as identify the chemical compounds of D. gigas extract. D. gigas was extracted successively with n-hexane, ethanol and methanol. The antioxidant activity was evaluated by determination of the half-maximal inhibi-tory concentration (IC50) values while the antibacterial activities of the extracts were determined by measuring the minimum inhibitory concentration (MIC). The results exhibited that the IC50 values of n-hexane, ethanolic and methanolic extracts were 336.18±0.0984, 89.16±0.0219 and 90.72±0.0894 μg/mL respectively. The ethanolic extract exhibited the highest AAI value (0.34) followed by metha-nolic extract (0.33) and n-hexane extract (0.09). Based on AAI val-ues, the extracts were classified as moderate antioxidants. The best MIC values were 625 μg/mL for both ethanolic and methanolic ex-tracts against S. aureus, while MIC values of all extracts against E. coli were >625 μg/mL. Based on MIC values, all of the extracts presented weak activity against both S. aureus and E.coli. The GC-MS analysis showed that there are up to 30 compounds construct-ed of the ethanolic extract. Three major compounds are ethyl oleate  (29.78%), n-hexadecanoic acid (17.54%) and oleic acid (10.65%).
RESEARCH OF WHEEL-RAIL WEAR DUE TO NON-SYMMETRICAL LOADING OF A FLAT CAR
Authors: Shatunov O. V. , Shvets A. O. , Kirilchuk O. A. , Shvets A. O.
Published: November 2019

Purpose. The paper is aimed at determining the influence of non-symmetrical loading of a flat car on the magnitude of the wear factor of a wheel-rail pair when changing the operation parameters that occur in operation. Methodology. The dynamic loading of the flat car, model 13-401 with typical three-piece bogies is studied using a model of spatial oscillations of a five-car coupling with the help of mathematical and computer simulation. Theoretical calculations are performed for the most dangerous sections of the railway track – small and medium radius curves in the range of permissible speeds. Findings. The indicators of wear of the rolling stock wheels and the rails are analysed on the example of flat cars in the presence of a longitudinal and transverse displacement of the load mass centre relative to the car symmetry centre. To obtain information on the effect of permissible deviations of the arrangement of cargo in the car on the magnitude of the dynamic loading of the wheel-rail contact, the authors performed theoretical studies of the spatial variations of the rail carriage and its interaction with the track. Originality. To determine the wear of the wheel-rail pair, the effect of displacement in two directions from the central axis of symmetry of the load gravity centre was studied, taking into account the value of the travel speed along the curved sections of the small and medium radius using a mathematical model of coupling of five freight cars. Practical value. As a result of the theoretical studies carried out, the authors assessed such factors as wear factor, directional force, and hunting of the wheel set of freight rolling stock in the event of load gravity centre displacement when moving along curved sections of the railway track. To establish the possible cause of intensive wear of the wheels and rails, the following parameters were analysed: lozenging of front bogie side frames; hunting of the left side frame of the front bogie; mutual longitudinal movement of the side frame and axle box of the front wheel set; mutual hunting of the left side frame of the bogie relative to the front wheel set.
CONTROL ORGANIZATION OF TECHNOLOGICAL PROCESSES OF RAILWAY STATIONS ON THE BASIS OF STATISTICAL METHODS
Authors: D. M. Kozachenko  , Y. N. Hermaniuk  , E. K. Manafov
Published: November 2019

Purpose. The article is aimed to develop statistical methods for monitoring the technological processes of railway stations` operation based on Stewhart charts. Methodology. The research is based on the methods of statistical quality control and the theory of railways operation. Findings. Existing methods for monitoring the implementation of technological processes of railway stations are focused on achieving quantitative indicators of their work while unconditionally fulfilling the necessary list of technological operations and observing train movement safety requirements. At the same time, the problem of monitoring compliance with quality indicators of railway stations` operation requires additional research. The main criterion for evaluating the quality of technological processes associated with the processing of trains, locomotives, cars, containers, cargoes, documents and information at railway stations is their duration. Considering that the time spent on processing these objects is random, it is proposed to use statistical methods, in particular, Stewhart charts, for monitoring and controlling the technological processes of the stations` operation. As an example, we discussed the processes of maintenance of freight train cars after departure and constructed Stewhart charts for Kleparov and Baladzhary stations. Operation analysis of both stations showed a significant influence of local conditions on the duration of train maintenance by departure, as well as significant deviations between its standard and actual duration. Originality. For the first time this paper proposed a method for controlling technological processes of railway stations based on the use of Stewhart control charts. Practical value. Application of the proposed method makes it possible, on the one hand, to adequately control the duration of technological processes and individual technological operations, which are usually random variables, and on the other hand, to evaluate the feasibility of implementing the norms established by technological processes. In addition, the organization at the stations of accumulating statistical information on the progress of technological processes will also significantly simplify the construction of adequate simulation models that take into account the stochastic nature of railway stations` functioning.
Intratumoral Immunotherapy—Update 2019
Authors: Hamid Omid , Ismail Rubina , Puzanov Igor
Published: November 2019

Intratumoral immunotherapies aim to trigger local and systemic immunologic responses via direct injection of immunostimulatory agents with the goal of tumor cell lysis, followed by release of tumor-derived antigens and subsequent activation of tumor-specific effector T cells. In 2019, a multitude of intratumoral immunotherapies with varied mechanisms of action, including nononcolytic viral therapies such as PV-10 and toll-like receptor 9 agonists and oncolytic viral therapies such as CAVATAK, Pexa-Vec, and HF10, have been extensively evaluated in clinical trials and demonstrated promising antitumor activity with tolerable toxicities in melanoma and other solid tumor types. Talimogene laherparepvec (T-VEC), a genetically modified herpes simplex virus type 1–based oncolytic immunotherapy, is the first oncolytic virus approved by the U.S. Food and Drug Administration for the treatment of unresectable melanoma recurrent after initial surgery. In patients with unresectable metastatic melanoma, T-VEC demonstrated a superior durable response rate (continuous complete response or partial response lasting ≥6 months) over subcutaneous GM-CSF (16.3% vs. 2.1%; p < .001). Responses were seen in both injected and uninjected lesions including visceral lesions, suggesting a systemic antitumor response. When combined with immune checkpoint inhibitors, T-VEC significantly improved response rates compared with single agent; similar results were seen with combinations of checkpoint inhibitors and other intratumoral therapies such as CAVATAK, HF10, and TLR9 agonists. In this review, we highlight recent results from clinical trials of key intratumoral immunotherapies that are being evaluated in the clinic, with a focus on T-VEC in the treatment of advanced melanoma as a model for future solid tumor indications.
The Impact of Nonsteroidal Anti-Inflammatory Drugs, Beta Blockers, and Metformin on the Efficacy of Anti-PD-1 Therapy in Advanced Melanoma
Authors: Wang Daniel Y. , McQuade Jennifer L. , Rai Rajat R. , Park John J. , Zhao Shilin , Ye Fei , Beckermann Kathryn E. , Rubinstein Samuel M. , Johnpulle Romany , Long Georgina V. , Carlino Matteo S. , Menzies Alexander M. , Davies Michael A. , Johnson Douglas B.
Published: November 2019

Anti–programmed cell death protein-1 (anti-PD-1) therapy has greatly improved outcomes of patients with melanoma; however, many fail to respond. Although preclinical studies suggest a potentially synergistic relationship with anti-PD-1 therapy and certain concurrent medications, their clinical role remains unclear. Here, we retrospectively evaluated the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and other drugs in 330 patients with melanoma treated with anti-PD-1 therapy from four academic centers. In the cohort, 37% of patients used NSAIDs including aspirin (acetylsalicylic acid; ASA; 47%), cyclooxygenase (COX)-2 inhibitors (2%), and non-ASA/nonselective COX inhibitor NSAIDs (59%). The objective response rates (ORRs) were similar in patients with NSAID (43.4%) and no NSAID (41.3%) use with no significant difference in overall suvival (OS). There was a trend toward improved progression-free survival (PFS) in patients who took NSAIDs (median PFS: 8.5 vs. 5.2 months; p = .054). Most patients (71.3%) took NSAIDs once daily or as needed. Multivariate analysis did not reveal an association with NSAID use with ORR, PFS, or OS. Concurrent use of metformin or beta blockers did not affect ORR, PFS, or OS. Our study found no conclusive association of concurrent NSAID or other medication use with improved outcomes in patients with melanoma treated with anti-PD-1 therapy. Larger and more systematic analysis is required to confirm these findings.
Synthesis of hexagonal nanozinc by arc discharge for antibacterial water treatment
Authors: Khalil Alaa Mahmoud , El-Khatib Ahmed Mohamed , El-khatib Mostafa
Published: November 2019

The arc discharge technique with some modifications was carried out to synthesize a high percentage of metallic zinc (Zn) nanoparticles (ZnNPs) with a high degree of structural perfection. The antibacterial potentials of the synthesized ZnNPs against common waterborne bacterial pathogens were compared as a more applicable disinfection method than conventional ones. The obtained characteristics (X-ray diffraction, energy-dispersive X-ray spectroscopy and transmission electron microscopy) of the prepared ZnNPs indicated their perfect hexagonal surface shape and the high purity of the zinc metal. Moreover, the prepared nanoparticles showed significant bacteriostatic and bactericidal effect against the various tested bacteria. The findings of this study support the use of ZnNPs as a strong antibacterial agent in water desalination plants and manufacturing of water filters. Moreover, the findings suggest the use of the arc discharge technique for preparing more effective nanometals with different shapes and high purity.
EROZİV ORAL LİKEN PLANUS’TA ENJEKTE EDİLEBİLEN TROMBOSİTTEN ZENGİN FİBRİN: ÇİFT KÖR, BÖLÜNMÜŞ AĞIZ, RANDOMİZE KONTROLLÜ PİLOT ÇALIŞMA
Authors: SAĞLAM Ebru , ÖZSAĞIR Zeliha Betül , ÜNVER Tuğba , TOPRAK Ali , BAYER ALINCA Suzan , TUNALI Mustafa
Published: November 2019

Amaç: Bu
çalışmanın amacı, enjekte edilebilen trombositten zengin fibrin'nin  (i-PRF) eroziv liken planus (EOLP) lezyonları
üzerindeki klinik etkisini değerlendirmek ve kortikosteroid tedavisi ile
karşılaştırmaktır.

Gereç ve Yöntem: Yanak
mukozasında çift taraflı EOLP bulunan 13 sistemik sağlıklı hastanın yanak
mukozalarının bir tarafına i-PRF, diğer tarafına intralezyonel kortikosteroid enjeksiyonu
yapılmıştır. Enjeksiyonlar 15 gün araya 4 seans tekrarlanmıştır. Sübjektif
değerlendirme belirteci olarak görsel analog skala (VAS), objektif
değerlendirme belirteci olarak Thongprasom skorları kullanılmıştır. Skorlamalar
tedaviden önce, son enjeksiyon seansından hemen sonra, tedavi sonrası 1. ay ve
tedavi sonrası 2. ay kontrol seanslarında yapılmıştır.

Bulgular: Gruplar
arası karşılaştırmada, başlangıç ve kontrol seanslarında VAS-Ağrı ,
VAS-Memnuniyet ve Thongprasom skorlarında istatistiksel olarak anlamlı bir fark
bulunamamıştır. Grup içi karşılaştırmalarda hem i-PRF uygulanan grupta (VAS-Ağrı
83,46 ± 16,25'ten 7,69 ± 9,92'ye düştü (p <0,001), VAS-Memnuniyet 26,54 ±
19,73'ten 87,31 ± 9,71'e yükseldi (p <0,001), Thongprasom skorları 4,85 ±
0,37'den 2,08 ± 1,04'e düştü (p = 0,001)), hem de kortikosteroid uygulanan
grupta (VAS-Ağrı 83,46 ± 16,25'ten 10,77 ± 14,27'ye düştü (p <0,001), VAS-Memnuniyet
26,54 ± 19,72'den 84,23 ± 13,52'ye yükseldi (p <0,001), Thongprasom skorları
4,54 ± 0,52'den 2,00 ± 1,22’e düştü (p = 0,001))  VAS-Ağrı ve Thongprasom skorlarının ortalama
değerlerinde istatistiksel olarak anlamlı bir düşüş görülürken, VAS-Memnuniyet
skorlarının ortalamasında  istatistiksel
olarak anlamlı bir artış gözlenmiştir. Sonuç: Bu pilot çalışma, i-PRF enjeksiyonunun EOLP lezyonların tedavisinde
altın standart kabul edilen kortikosteroid enjeksiyonuna benzer derecede etkili
olabileceğini göstermiştir.
Modelling Undergraduate Student Engagement in China
Authors: Zhang Zhe
Published: November 2019

Against the background of the international audit culture and the associated higher education league tables, student engagement has become a pervasive indicator for measuring the education quality of institutions. This paper reports findings from a study investigating undergraduate student engagement at a Chinese university. Data were collected through questionnaire survey, individual interview and group interview methods. Survey findings will be the focus of attention of this paper. Five factors emerged from an exploratory factor analysis of the data: Effective Teaching Practices, Personal Development, Supportive Campus Environment, Collaborative, Reflective & Integrative Learning, and Quality of Interactions (Student-Staff). Models about students’ engagement and experiences (academic and non-academic) were developed on the basis of these factors and two background variables (School and Year), using a multi-model building strategy. The findings contribute to the dominant paradigm of student engagement by specifying the magnitude of significant indicators mediating different aspects of students’ engagement and experiences, and will inform the future policies and practices of institutions.
A Comparative Study on the Washback Effects of Teacher Feedback plus Intelligent Feedback versus Teacher Feedback on English Writing Teaching in Higher Vocational College
Authors: Wang Jiachun
Published: November 2019

For college students majoring in English, English writing is a relatively difficult project. How to effectively improve the English writing ability of students of English majors in vocational colleges is an important issue that every college teacher needs to pay attention to. As a teaching tool, the intelligent computer automated essay evaluation system can help students improve their English writing ability more objectively, efficiently and accurately. This paper employs the intelligent computer automated essay evaluation system as a teaching tool, taking college students as the research object, and carried out an 18-week online self-writing teaching experiment and traditional writing experiment. This paper conducts a comparative study on the washback effects of teacher feedback plus intelligent feedback versus teacher feedback on English writing teaching in higher vocational college, which provides a prominent research value and research significance for the reform and innovation of English writing teaching in higher vocational colleges.
Research on Intelligent Learning APP in Junior English Vocabulary Teaching
Authors: Wang Ling
Published: November 2019

Vocabulary, as one of the most difficult problems for students and teachers, is also one of the most important elements in traditional teaching. This thesis is based on the problems existing in traditional vocabulary teaching and under the guidance of the mobile learning theory, the constructivism theory and the humanism theory. This thesis researches the application of intelligent Learning APP in Junior English vocabulary teaching .The research shows that the application of intelligent Learning APP, as one of the products of modern science and technology, is applied in Junior English vocabulary teaching. It effectively combines after-class teaching with in-class teaching, pays attention to students' individuality, improves teachers' teaching quality and reduces teaching pressure. The application of intelligent Learning APP has made up for the shortcomings of traditional teaching, stimulated students' interest in learning and made the teaching process more interesting.
A Genre-analysis of the Discussion Section of Iranian and English ELT Theses: A Comparative Study
Authors: Massoum Yassaman Hosseini , Yazdanmehr Elham
Published: November 2019

The present research aimed to conduct a genre analysis of native (English) and non-native (Iranian) English speakers’ M.A theses of Teaching English as a Foreign Language (TEFL) students to find any significant differences in their Discussion section structures according to the constitutive moves and steps. It also aimed to explore and compare the distribution of obligatory, conventional and optional moves and steps in the two corpuses. To this aim, 20 theses were randomly selected from well-known English Speaking Universities (Portland State University, University of Toledo, Ohio State University and University of Birmingham) to compare with 20 theses from Iran. The move analysis model by Yang and Allison (2003) was employed, which was specifically used in Applied Linguistics. Chi-squared test was run to make the comparison. The results revealed statistically significant differences between the genre followed in the Discussion sections of Iranian and non-Iranian TEFL M.A. theses. The most significant divergence was found in summarizing the study. English-speaking TEFL thesis writers tended to summarize the study in Discussion section significantly more than Iranian writers. Statistically significant differences were also found in the distribution of obligatory, conventional and optional moves. English-speaking writers indicated limitations in the Discussion section significantly more than Iranian writers. This shows Iranian TEFL M.A. writers are more reserved to discuss limitations. These results can be used effectively in M.A. courses of TEFL to raise students’ awareness and prevent them from overstating or understating certain constituent parts of the Discussion section in theses.
Miniature Bandpass Microwave Filter with Ultradeep Suppression in a Wide Stopband
Authors: Savishnikov Maksim O. , Dmitriev Dmitry D. , Kabanov Eduard D.
Published: November 2019

The paper presents the results of a study of the design of a miniature band-pass filter based on multi-conductor strip resonators. Using the software for electrodynamic analysis, a sixthorder band-pass filter on seven-conductor resonators was designed and manufactured. Designed filter is characterized by small size and deep repression of the stop band. The measured filter characteristics exceed the characteristics of known analogs. The measured width of the highfrequency stop band of 24 times the center frequency of the bandwidth at the level of suppression at least 160 dB
ÖRME GİYSİ TASARIMINDA POSTMODERN SANATA YÖNELİK EĞİLİMLER
Authors: OSKAY Nazan
Published: November 2019

Sanat,
doğası gereği sürekli değişmek zorundadır. Her değişim başlangıçta tepki ile
karşılansa bile kısa bir süre içinde alternatifini yaratacak potansiyeli içinde
taşıyarak kabul görmektedir. Sanatın sürekliliği değişim olgusuna bağlıdır.
Sanatın değişim ve dönüşümleri eş zamanlı olmasa bile ayrı zamanlarda
kültürleri, bu bağlamda da insanın günlük yaşantılarını ve beğenilerini
dönüştürmektedir. Sanattaki değişim hareketleri birçok sanatta görüldüğü gibi
tekstil sanatını etkileyerek sanatçı ve tasarımcıların farklı arayışlar
içerisine girmesini sağlamıştır.

Tekstil,
teknolojik üretim anlamında da sanayi devriminin ardından, meta değeri yüksek,
işlevsel, endüstri tasarımı boyutunda algılanır hale gelmiştir. İşlevsel
oluşunun yanı sıra, kültürel kimliklerin, toplumsal statülerin, cinsel yansımaların
ve gündelik hayatın beğeni dilini oluşturmuştur. Özellikle 1960’lı yıllardan
günümüze post modern atmosfer içinde yeniden biçim alan tekstil ya da lif
sanatı, çok farklı dönüşümler geçirmiştir.

Bu
süreçte tekstil tasarımcısı üst başlığı altında yer alan örme tasarımcısı, sanatçı
kimliğini benimsemiştir. Örme tasarımı; postmodern yaşam tarzı içinde, artık
işlevsel ve ekonomik değer nesnesi olarak ürün vermekle sorumlu değildir; aynı
zamanda çağın estetik seçkilerinin arasında yer alabilecek tasarımlar
gerçekleştirmektedir.

Bu
araştırmada postmodern sürecin örme tasarımının üzerindeki etkileri
irdelenecektir. Araştırmanın materyalini, 1960’lardan günümüze tartışmalara
neden olmuş, postmodernizm kavramı ve örme giysi tasarımı üzerindeki etkileri
oluşturmaktadır. Çalışma, veri toplama ve analiz sürecinden oluşmaktadır.
Çalışmada, konuya ilişkin kitap, tez, makale bildiri vb. yazılı kaynaklardan
yararlanılmıştır.
SOCIO-POLITICAL VIEWS OF HRYGORYI HOLOSKEVYCH
Authors: Mohylnyi L. , Liashchenko O.
Published: November 2019

At the end of the 19th and in the early 20th century the Ukrainian intelligentsia attached great significance to a personal contribution of everyone in the field of science and culture to the development of one’s homeland. One of those who shared this opinion was Hrygoryi Kostantynovych Holoskevych. He worked at the Petersburg publishing house ''Drukar'' until 1917, then, in August 1917, he moved to Kyiv and joined the Ukrainian Central Rada and the Ukrainian Party of Socialist-Federalists, which was headed by S. Yefremov. Also, he supported the Ukrainian People's Republic in the struggle against the Bolsheviks.

In the Ukrainian and foreign historiography, the social and political views of Holoskevych have received little attention. Therefore, in the current research, the evolution of H. Holoskevych's views during the revolutionary events and the struggle for independence in 1917-1920's have been analyzed. His autonomous beliefs, which were formed under the influence of the Ukrainian community of St. Petersburg and his participation in the Ukrainian national movement, have been defined. The research has revealed that, like most participants in the Ukrainian national movement, Holoskevych came to a firm belief that the formation of an independent state, which could finally solve the national, social, economic, scientific, and educational issues of the Ukrainian people, became an urgent need in his time. One of the ways of such self-affirmation was his scientific work in the field of linguistics. The little-known side of H. Holoskevych's activities was his participation in the underground anti-Bolshevik associations, namely in the Brotherhood of Ukrainian Statehood (BUD), which sought to restore the UPR. In the article, it has been revealed that the members of the BUD tried to become the focal point of the national movement on the territory of Kyiv region, condemned the Bolshevik policy of war communism, treated the NEP and the policy of Ukrainization with a great deal of mistrust and caution. Taking into consideration the fact that so-called marginal representatives of the Ukrainian movement, including H. Holoskevych, have been little explored so far, the research on the socio-political views of the figures of the Ukrainian national movement is extremely urgent in a modern scientific discourse.
Rapprochement Urbanism
Authors: Pierce West Kendon , Gregory Alexis
Published: November 2019

Rapprochement urbanism addresses how wild environments can be accommodated in urban spaces to create more sustainable and resilient cities. Referring to the dual realities of wilderness and urbanity, this design strategy explores the interaction of their two structures to replace the misconception that cities are built “on” the natural environment, with the assertion that cities are built “in” it. Jackson, Mississippi currently treats adjacent vibrant ecological habitats as forgotten back alleys rather than urban assets. Utilizing interventions within a holistic plan, rapprochement urbanism combats urban sprawl and “back alley” attitudes, mitigates stormwater challenges, and facilitates human and animal spatial needs. Rapprochement urbanism, through the rewilding of Jackson, MS, allows architects to more directly impact and improve the ecological sustainability of this city of 170,000 inhabitants.[i]

 

i“Jackson, Mississippi.” Jackson, Mississippi (MS) Profile: Population, Maps, Real Estate, Averages, Homes, Statistics, Relocation, Travel, Jobs,Hospitals, Schools, Crime, Moving, Houses, News, Sex Offenders. http://www.city-data.com/city/Jackson -Mississippi.html (Accessed November 01, 2018).
Impact of Chilling Requirement on Budburst, Floral Development and Hormonal Level in Buds of Early and Late Apple Varieties (Malus sylvestris, Mill) under Natural Conditions
Authors: El-Yazal Mohamed A. Seif
Published: November 2019

In order to produce the physiological bases for choosing early- flowering varieties that may avoid the depleted low winter temperatures, the early and late- opining apple variety Barkhar, Local and Strakhan (Malus sylvestris) were wont to study the relation between the seasonal changes and these balance of endogenous hormones and flower opining date. An improved understanding of the factors governing budburst and development, and their underlying mechanisms is crucial for management of trees performance and yielding. This study investigated variations in chilling requirements, bud burst and development in early and late varieties of apple trees. The budburst and hormonal profile of flower and vegetative buds of early and late varieties were additionally investigated. Results showed less bud burst in late varieties than in early ones. In the former, there were increased in promoters (indole-3-acetic acid and gibberellins) at budburst. Although endogenous inhibitors levels of abscisic acid were considerably reduced by bud development in all varieties. We conclude that late varieties (Strakhan) are less economical in manufacturing new growth, as indicated by less bud vigor at budburst than early varieties (Barkhar and local) and show a marked differential hormonal pattern throughout bud development compared to early varieties.
Investigation into the research on doctoral writing: A synthesis of recent research (2010-2019)
Authors: Guo Xia
Published: November 2019

Doctoral writing has been concerned by linguistic scholars and the practitioners of English for academic purposes. This review explores the literature on doctoral writing which got published in peer-reviewed international journals of English between 2010 and 2019 to examine three questions: (1) From which perspectives do the recent researches adopt when examining doctoral writing of the ESOL students? (2) What methodology do the authors apply to research doctoral writing? (3) What kind of text or resource was analyzed by the authors? The goal of the review is to provide the pedagogical suggestions to the future teaching of doctoral writing and viable supports for the writing practice of doctoral students by a comprehensive analysis of the current research. After the overall search on Scopus, 210 titles and abstracts have been searched out through a combination of search terms. The inclusion and exclusion criteria have been used to identify the qualified articles for this study and disqualify the possibly irrelevant articles from the included. Ultimately, 82 articles have been confirmed to be further reviewed for the solution of research questions. This review indicates the relationship between doctoral writing and pedagogical and social context is complex, and thus necessary supports from inside and outside of doctoral community need to be given to improve the writing competence of doctoral students.
Digital Light Processing Based Three-dimensional Printing for Medical Applications
Authors: Zhang Jiumeng , Hu Qipeng , Wang Shuai , Tao Jie , Gou Maling
Published: November 2019

An additive manufacturing technology based on projection light, digital light processing (DLP), three-dimensional (3D) printing, has been widely applied in the field of medical products production and development. The precision projection light, reflected by a digital micromirror device of million pixels instead of one focused point, provides this technology both printing accuracy and printing speed. In particular, this printing technology provides a relatively mild condition to cells due to its non-direct contact. This review introduces the DLP-based 3D printing technology and its applications in medicine, including precise medical devices, functionalized artificial tissues, and specific drug delivery systems. The products are particularly discussed for their significance in medicine. This review indicates that the DLP-based 3D printing technology provides a potential tool for biological research and clinical medicine. While, it is faced to the challenges of scale-up of its usage and waiting period of regulatory approval.
Possibility estimation of 3D scene reconstruction from multiple images
Authors:   Samara National Research University, Moskovskoe Shosse 34А, Samara, Russia, 443086, Dmitriev Egor , Myasnikov Vladislav ,   Samara National Research University, Moskovskoe Shosse 34А, Samara, Russia, 443086,   Image Processing Systems Institute of RAS - Branch of the FSRC "Crystallography and Photonics" RAS, Molodogvardejskaya street 151, Samara, Russia, 443001
Published: November 2019

This paper presents a pixel-by-pixel possibility estimation of 3D scene reconstruction from multiple images. This method estimates conjugate pairs number with convolutional neural networks for further 3D reconstruction using classic approach. We considered neural networks that showed good results in semantic segmentation problem. The efficiency criterion of an algorithm is the resulting estimation accuracy. We conducted all experiments on images from Unity 3d program. The results of experiments showed the effectiveness of our approach in 3D scene reconstruction problem.
The effect of Topotecan on oxidative stress in MCF-7 human breast cancer cell line.
Authors: Timur Mujgan , Akbas S Halide , Ozben Tomris
Published: November 2019

Topotecan, a semisynthetic water-soluble derivative of camptothecin exerts its cytotoxic effect by inhibiting topoisomerase I and causes double-strand DNA breaks which inhibit DNA function and ultimately lead to cell death. In previous studies it was shown that camptothecin causes ROS formation. The aim of this study was to investigate if Topotecan like camptotecin causes oxidative stress in MCF-7 human breast cancer cell line. Determining the oxidant effect of Topotecan may elucidate a possible alternative mechanism for its cytotoxicity.
MCF-7 cells were cultured and exposed to Topotecan for 24 h at 37 degrees C. The viability of the cells (% of control) was measured using the colorimetric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Lipid peroxidation (TBARS), protein oxidation (carbonyl content), sulfhydryl, glutathione (GSH) levels, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities were determined in MCF-7 cells with and without Topotecan incubation.
We found the IC(50) concentration of Topotecan as 0.218 microM in MCF-7 cells. This concentration of Topotecan was used in the incubations of the cells. Our data indicated increased oxidative status, as revealed by increased lipid peroxidation and protein oxidation, and decreased GSH and sulfhydryl levels in MCF-7 cells exposed to Topotecan compared to control cells. In contrast, there was a slight increase in SOD and a significant increase in GPx and catalase activity in MCF-7 cells incubated with Topotecan compared to the control.
These results support our hypothesis that Topotecan increases oxidative stress in MCF-7 cells.
Methylxanthines (caffeine, pentoxifylline and theophylline) decrease the mutagenic effect of daunomycin, doxorubicin and mitoxantrone.
Authors: Piosik Jacek , Gwizdek-Wiśniewska Anna , Ulanowska Katarzyna , Ochociński Jakub , Czyz Agata , Wegrzyn Grzegorz
Published: November 2019

Previously performed experiments showed that methylxanthines, especially caffeine, may protect cells against cytostatic or cytotoxic effects of several aromatic compounds. One of the proposed mechanisms of this protection is based on stacking interactions between pi electron systems of polycyclic aromatic molecules. In this work, we demonstrate that caffeine and other methylxanthines--pentoxifylline and theophylline--significantly decrease mutagenicity of the anticancer aromatic drugs daunomycin, doxorubicin and mitoxantrone. The spectrophotometric titration of these aromatic compounds by methylxanthines indicated formation of mixed aggregates. The concentrations of free active forms of the drugs decreased when the concentrations of methylxanthines increased in the mixture. Therefore, likely methylxanthines may play a role of scavengers of the free active forms of daunomycin, doxorubicin and mitoxantrone.
Molecules released by helminth parasites involved in host colonization.
Authors: Dzik Jolanta M
Published: November 2019

Parasites are designed by evolution to invade the host and survive in its organism until they are ready to reproduce. Parasites release a variety of molecules that help them to penetrate the defensive barriers and avoid the immune attack of the host. In this respect, particularly interesting are enzymes and their inhibitors secreted by the parasites. Serine-, aspartic-, cysteine-, and metalloproteinases are involved in tissue invasion and extracellular protein digestion. Helminths secrete inhibitors of these enzymes (serpins, aspins, and cystatins) to inhibit proteinases, both of the host and their own. Proteinases and their inhibitors, as well as helminth homologues of cytokines and molecules containing phosphorylcholine, influence the immune response of the host biasing it towards the anti-inflammatory Th2 type. Nucleotide-metabolizing enzymes and cholinesterase are secreted by worms to reduce inflammation and expel the parasites from the gastrointestinal tract. An intracellular metazoan parasite, Trichinella spiralis, secretes, among others, protein kinases and phosphatases, endonucleases, and DNA-binding proteins, which are all thought to interfere with the host cellular signals for muscle cell differentiation. Secretion of antioxidant enzymes is believed to protect the parasite from reactive oxygen species which arise from the infection-stimulated host phagocytes. Aside from superoxide dismutase, catalase (rarely found in helminths), and glutathione peroxidase (selenium-independent, thus having a poor activity with H(2)O(2)), peroxiredoxins are probably the major H(2)O(2)-detoxifying enzymes in helminths. Secretion of antioxidant enzymes is stage-specific and there are examples of regulation of their expression by the concentration of reactive oxygen species surrounding the parasite. The majority of parasite-secreted molecules are commonly found in free-living organisms, thus parasites have only adapted them to use in their way of life.
Synthesis, antimicrobial activity and structural studies of low molecular mass lysine dendrimers.
Authors: Janiszewska Jolanta , Urbańczyk-Lipkowska Zofia
Published: November 2019

Four low molecular mass lysine dendrimers were synthesized by Boc chemistry in solution (155 and 169) and Fmoc chemistry on solid support (P2 and P13). The structure and fragmentation mode of the above dendrimers was investigated in gas phase by the LSI-MS and ESI-MS techniques. (1)H and (13)C NMR analysis in solution (d(6)-DMSO) allowed to confirm the correct structure. Antimicrobial activities of the dendrimers against Staphylococcus aureus, Escherichia coli and Candida albicans confirmed our hypothesis that the dendrimer structure can be used for construction of molecules interacting with biological membranes.
Differential stability of mitochondrial mRNA in HeLa cells.
Authors: Piechota Janusz , Tomecki Rafał , Gewartowski Kamil , Szczesny Roman , Dmochowska Aleksandra , Kudła Marek , Dybczyńska Lien , Stepien Piotr P , Bartnik Ewa
Published: November 2019

The physiological significance and metabolism of oligoadenylated and polyadenylated human mitochondrial mRNAs are not known to date. After study of eight mitochondrial transcripts (ND1, ND2, ND3, ND5, CO1, CO2, ATP6/8 and Cyt. b) we found a direct correlation between the half-lives of mitochondrial mRNAs and their steady-state levels. Investigation of the mt-mRNA decay after thiamphenicol treatment indicated that three transcripts (ND2, ND3 and Cyt. b) are significantly stabilized after inhibition of mitochondrial translation. Careful analysis one of them, ND3, showed that inaccurate processing of the H-strand RNA precursor may occasionally occur between the ND3 and tRNA(Arg) locus leading to synthesis of ND3 mRNAs lacking the STOP codon. However, analysis of the oligo(A) fraction observed in case of the ND3 indicates that partially polyadenylated mRNAs are linked rather to the transcription process than to the translation-dependent deadenylation. Analysis of ND3 mRNA turnover in cells with siRNA-mediated knock-down of the mitochondrial poly(A) polymerase shows that strongly decreased polyadenylation does not markedly affect the decay of this transcript. We present a model where oligoadenylated mitochondrial transcripts are precursors of molecules containing full length poly(A) tails.