bluuebunny/crossref_metadata_2025 huggingface dataset:
Improvement of High-Volume Fly Ash Cementitious Material Using Single Alkali Activation
Authors: Chalee Wichian , Soeurt Reaksmey , Pachana Pumipat , Songpiriyakij Smith
Published: November 2021

This research aimed to present the improvement of the cementitious material in high-volume fly ash using only one alkali activator. Fly ash was used as a partial replacement for Portland cement type I, varying from 0 to 60% by weight of the binder. Concentrations of NaOH varying from 0.00 to 1.25 molar were used as alkali activator. Paste properties and mortar compressive strength at the ages of 3, 7, 14, 28, 60, and 90 days of water curing were investigated. The results reveal that fly ash paste with an alkali activator provides shorter initial setting time when compared to control paste without alkali activator. The use of 0.50 molar NaOH concentration in mortar containing fly ash not exceeding 50% by weight of binder provides the highest compressive strength at any age of curing. At that concentration, there is a significant increase in the 28-day compressive strength of up to 45% over that of the control mortar. In addition, higher NaOH concentration (not exceeding 1.00 molar) has a significant positive effect on the compressive strength of mortar with higher fly ash content, especially over longer curing periods.
Growth and neurodevelopmental status in patients with retinopathy of prematurity treated with intravitreal bevacizumab: a case–control study
Authors: Abrishami Majid , Boskabadi Hassan , Abrishami Mojtaba , Shekarchian Farid , Khadem-Rezaiyan Majid , Shoeibi Nasser
Published: November 2021

Background

The current study aimed to evaluate growth and neurodevelopmental status in patients with retinopathy of prematurity (ROP) treated with intravitreal bevacizumab (IVB).

Methods

This historical cohort study was conducted on neonates with ROP who were treated with IVB and age and birth weight-matched controls who did not need IVB. Apgar score less than five, history of blood transfusion and history of infectious diseases were among exclusion criteria. Indirect ophthalmoscopic examinations were performed till complete retinal vascularization. Growth and neurodevelopmental status were evaluated by Age and Stages Questionnaire (ASQ) at the ages of 6, 12, and 18 months. Developmental milestones were assessed in five areas (gross motor, fine motor, personal-social status, problem-solving, and relationship) and overall issues.

Results

A total of 34 cases and 36 controls were included in the present study. Birth weight and corrected gestational age were not statistically different between the groups. In a follow-up period of 18 months, bevacizumab was effective as a primary treatment in the treatment of severe cases of ROP. There was no significant difference between the two groups regarding the five areas and overall issues in follow-up intervals (P > 0.05).

Conclusions

The obtained results did not show any growth and neurodevelopmental differences between treatment-naïve infants and those receiving IVB for the treatment of ROP.
A rare case as different cause of retropharyngeal and spinal epidural abscess: spondylodiscitis
Authors: İsayev Nurlan , Yücel Levent , Akyıldız Hatice Seçil , Mammadkhanlı Orkhan , Başak Hazan , Doğan İhsan
Published: November 2021

Background

Retropharyngeal abscess (RPA) is a life-threatening, dangerous condition and uncommon in adults. The coexistence of RPA, cervical spinal epidural abscess (CSEA), and spondylodiscitis is extremely rare.

Case presentation

We present a case with a retropharyngeal and epidural abscess caused by spondylodiscitis. A 61-year-old man was referred to our clinic with the complaints of sore throat, limitation in neck range of motion, numbness, and weakness in the left arm and the left ear for one month. The airway was not obstructed. Neurological deficits were detected in his left arm. Cervical computed tomography revealed a 50 × 30 × 15 mm retropharyngeal abscess. Cervical magnetic resonance imaging showed abscess, C5–6 spondylodiscitis and epidural abscess, and myelopathic signal changes in the C3–7 spinal cord. The abscess was drained, and C5–6 discectomy was performed. The patient was discharged with cervical collar and antibiotics.

Conclusions

Multidisciplinary approach that consists of otolaryngologist, neurosurgeon, and infectious disease specialist is needed to avoid complications and any delay.
The role of diaphragmatic ultrasound as a predictor of successful extubation from mechanical ventilation in respiratory intensive care unit
Authors: Mohamed Randa Salah Eldin , Mohamed Abeer Salah Eldin , Fathalah Waleed Fouad , Mohamed Mohamed Farouk , Ahmed Ahmed Aelgharib
Published: November 2021

Background

The diaphragm muscle whose dysfunction may be very common in patients undergoing mechanical ventilation (Ferrari G, De Filippi G, Elia F, Panero F, Volpicelli G, Aprà F. Crit Ultrasound J 6:8, 2014). Aim: To evaluate real-time ultrasound in the evaluation of diaphragmatic thickening, thickening fraction, and/or excursion to predict extubation outcomes. We aimed to compare these parameters with other traditional weaning measures is a fundamental.

Results

Out of 80 included patients, 20 (25%) have failed extubation. Diaphragmatic thickening (DT), thickening fraction (DTF), and/or excursion (DE) were significantly higher in the successful group compared to those who failed extubation (p < 0.05). Cutoff values of diaphragmatic measures associated with successful extubation (during tidal breathing) were ≥ 17 mm for DE; ≥ 2.1 cm for DT inspiration; ≥ 15.5 mm for DT expiration, functional residual capacity (FRC); and ≥ 32.82% for DTF %, giving 68%, 95%, 62%, and 90% sensitivity, respectively, and 65%, 100%, 100%, and 75% specificity, respectively. Cutoff values of diaphragmatic parameters associated with successful extubation (during deep breathing) were > 28.5 mm DT Insp, total lung capacity (TLC); >22.5mm DT Exp (RV); >37 DTF %; and > 31 mm DE, giving 100%, 73%, 97%, and 75% sensitivity and 65%, 75%, 100%, and 55% specificity, respectively. Rapid shallow breathing index (RSBI) had 47% sensitivity but 90% specificity.

Conclusion

Ultrasound evaluation of diaphragmatic parameters could be a good predictor of weaning in patients who passed the T-tube.
The Strength of Alpha Oscillations in the Electroencephalogram Differently Affects Algorithms Used for Anesthesia Monitoring
Authors: Weyer Clara , Prötzl Eva , Kinateder Thomas , Nowak Fabian , Husemann Cornelius , Hautmann Hubert , Kratzer Stephan , Schneider Gerhard , Kreuzer Matthias
Published: November 2021

BACKGROUND:

Intraoperative patient monitoring using the electroencephalogram (EEG) can help to adequately adjust the anesthetic level. Therefore, the processed EEG (pEEG) provides the anesthesiologist with the estimated anesthesia level. The commonly used approaches track the changes from a fast- and a low-amplitude EEG during wakefulness to a slow- and a high-amplitude EEG under general anesthesia. However, besides these changes, another EEG feature, a strong oscillatory activity in the alpha band (8–12 Hz), develops in the frontal EEG. Strong alpha-band activity during general anesthesia seems to reflect an appropriate anesthetic level for certain anesthetics, but the way the common pEEG approaches react to changes in the alpha-band activity is not well explained. Hence, we investigated the impact of an artificial alpha-band modulation on pEEG approaches used in anesthesia research.

METHODS:

We performed our analyses based on 30 seconds of simulated sedation (n = 25) EEG, simulated anesthesia (n = 25) EEG, and EEG episodes from 20 patients extracted from a steady state that showed a clearly identifiable alpha peak in the density spectral array (DSA) and a state entropy (GE Healthcare) around 50, indicative of adequate anesthesia. From these traces, we isolated the alpha activity by band-pass filtering (8–12 Hz) and added this alpha activity to or subtracted it from the signals in a stepwise manner. For each of the original and modified signals, the following pEEG values were calculated: (1) spectral edge frequency (SEF95), (2) beta ratio, (3) spectral entropy (SpEntr), (4) approximate entropy (ApEn), and (5) permutation entropy (PeEn).

RESULTS:

The pEEG approaches showed different reactions to the alpha-band modification that depended on the data set and the amplification step. The beta ratio and PeEn decreased with increasing alpha activity for all data sets, indicating a deepening of anesthesia. The other pEEG approaches behaved nonuniformly. SEF95, SpEntr, and ApEn decreased with increasing alpha for the simulated anesthesia data (arousal) but decreased for simulated sedation. For the patient EEG, ApEn indicated an arousal, and SEF95 and SpEntr showed a nonuniform change.

CONCLUSIONS:

Changes in the alpha-band activity lead to different reactions for different pEEG approaches. Hence, the presence of strong oscillatory alpha activity that reflects an adequate level of anesthesia may be interpreted differently, by an either increasing (arousal) or decreasing (deepening) pEEG value. This could complicate anesthesia navigation and prevent the adjustment to an adequate, alpha-dominant anesthesia level, when titrating by the pEEG values.
Empowering Women as Leaders in Pediatric Anesthesiology: Methodology, Lessons, and Early Outcomes of a National Initiative
Authors: Schwartz Jamie McElrath , Markowitz Scott D. , Yanofsky Samuel D. , Tackett Sean , Berenstain Laura K. , Schwartz Lawrence I. , Flick Randall , Heitmiller Eugenie , Fiadjoe John , Lee Helen H. , Honkanen Anita , Malviya Shobha , Cladis Franklyn P. , Lee Jennifer K. , Deutsch Nina
Published: November 2021

Research has shown that women have leadership ability equal to or better than that of their male counterparts, yet proportionally fewer women than men achieve leadership positions and promotion in medicine. The Women’s Empowerment and Leadership Initiative (WELI) was founded within the Society for Pediatric Anesthesia (SPA) in 2018 as a multidimensional program to help address the significant career development, leadership, and promotion gender gap between men and women in anesthesiology. Herein, we describe WELI’s development and implementation with an early assessment of effectiveness at 2 years. Members received an anonymous, voluntary survey by e-mail to assess whether they believed WELI was beneficial in several broad domains: career development, networking, project implementation and completion, goal setting, mentorship, well-being, and promotion and leadership. The response rate was 60.5% (92 of 152). The majority ranked several aspects of WELI to be very or extremely valuable, including the protégé-advisor dyads, workshops, nomination to join WELI, and virtual facilitated networking. For most members, WELI helped to improve optimism about their professional future. Most also reported that WELI somewhat or absolutely contributed to project improvement or completion, finding new collaborators, and obtaining invitations to be visiting speakers. Among those who applied for promotion or leadership positions, 51% found WELI to be somewhat or absolutely valuable to their application process, and 42% found the same in applying for leadership positions. Qualitative analysis of free-text survey responses identified 5 main themes: (1) feelings of empowerment and confidence, (2) acquisition of new skills in mentoring, coaching, career development, and project implementation, (3) clarification and focus on goal setting, (4) creating meaningful connections through networking, and (5) challenges from coronavirus disease 2019 (COVID-19) and the inability to sustain the advisor-protégé connection. We conclude that after 2 years, the WELI program has successfully supported career development for the majority of protégés and advisors. Continued assessment of whether WELI can meaningfully contribute to attainment of promotion and leadership positions will require study across a longer period. WELI could serve as a programmatic example to support women’s career development in other subspecialties.
Σχεδιασμός, σύνθεση και βιολογικές μελέτες πολυφαινολικών παραγώγων
Authors: Παγώνη Αικατερίνη
Published: November 2021

Η παρούσα διατριβή έχει δύο θέματα ως αντικείμενα έρευνας. Το πρώτο αντικείμενο αφορά τη σύνθεση ενώσεων κατά της νόσου του Αλτσχάιμερ, μιας πολυσχιδούς ασθένειας, μέσω της στρατηγικής σύνθεσης φαρμάκων πολλαπλών στόχων. Χρησιμοποιώντας ως μητρικές ενώσεις πολυφαινολικά οξέα και λιποϊκό οξύ, και ως συνδετικά μόρια αμινοαλκοόλες ή διαμίνες, έγινε σύνθεση υβριδικών μορίων, τα οποία μελετήθηκαν ως προς τις φυσικοχημικές και βιολογικές τους ιδιότητες. Το υβριδικό παράγωγο του φερουλικού οξέος επέδειξε τη βέλτιστη αντιοξειδωτική και νευροπροστατευτική δράση, που σε συνδυασμό με την σταθερότητα της ένωσης, το καθιστά ως ένα αρκετά ελπιδοφόρο υβριδικό μόριο.Το δεύτερο αντικείμενο της εργασίας, αφορά τη σύνθεση νέων αναστολέων κατά του ενζύμου της ουρεάσης. Σε αυτό το πλαίσιο, έγινε σύνθεση διλειτουργικών μορίων, τα οποία αλληλεπιδρούν ταυτόχρονα με τα ιόντα Ni2+ (μέσω ενός φωσφονικού/καρβοξυλικού συστήματος) και με τη σουλφυδρυλομάδα της Cys322 του ενεργού κέντρου του ενζύμου (μέσω ενός κατεχολικού δακτυλίου). Οι αναστολείς μελετήθηκαν ως προς την ανασταλτική τους δράση έναντι του ενζύμου, ενώ πραγματοποιήθηκαν και πειράματα μοριακής μοντελοποίησης για να εξακριβωθεί ο τρόπος σύνδεσης τους με το ένζυμο. To 3-((1-(3,4-διυδροξυφαινυλο)-3-μεθοξυ-3-οξοπροπυλ)(υδροξυ)φωσφορυλο)προπανοϊκό οξύ επέδειξε την ισχυρότερη, μη αντιστρεπτή ανασταλτική δράση με τιμή kinact/KI = 10420 s-1 M-1.Τέλος, στο ίδιο πλαίσιο, έγινε σύνθεση διλειτουργικών αναστολέων της ουρεάσης, οι οποίοι βασίζονται στη δομή της ουρίας. Έτσι, παρασκευάστηκαν κατεχολικά παράγωγα ουρίας, θειουρίας και καρβαμικά παράγωγα, τα οποία μελετήθηκαν ως προς την ανασταλτική τους ισχύ. Η 1-κυκλοεξυλο-3-(3,4-διυδροξυβενζυλ)ουρία παρουσιάσε την ισχυρότερη ανασταλτική δράση έναντι του ενζύμου της ουρεάσης με IC50 = 571.7 mM.
Evidence-based research impact praxis: Integrating scholarship and practice to ensure research benefits society
Authors: Jensen Eric A. , Reed Mark , Jensen Aaron M. , Gerber Alexander
Published: November 2021

Effective research impact development is essential to address global challenges. This commentary highlights key issues facing research impact development as a nascent professional field of practice. We argue that those working on research impact should take a strategic, ‘evidence-based’ approach to maximize potential research benefits and minimize potential harms. We identify key features of evidence-based good practice in the context of research impact work. This includes integrating relevant research and theory into professional decision-making, drawing on a diversity of academic disciplines offering pertinent insights. Such an integration of scholarship and practice will improve the capacity of research impact work to make a positive difference for society. Moving the focus of research impact work to earlier stages in the research and innovation process through stakeholder engagement and anticipatory research can also boost its effectiveness. The research impact evidence base should be combined with the right kind of professional capacities and practical experience to enhance positive impact. Such capacities need to be developed through relevant education and training, for example, in participatory methods and social inclusion. Such training for research impact work needs to forge strong links between research impact scholarship and practice. Finally, there is a need for improvements in the evidence base for research impact to make it more practically useful.
MANAGEMENT COMPETENCE OF THE HEAD: MONOGRAPH
Authors: Belova Elena N.
Published: November 2021

The monograph presents the results of a study of the organizational and pedagogical conditions for the formation of managerial competence of the head of an educational institution in the sphere of culture, which has important theoretical and practical importance for the successful development of educational institutions in the sphere of culture in the context of the modernization of Russian art education. The essence, components and criterial characteristics of the formation of managerial competence of the head are considered. It is intended for researchers, teachers, students of management specialties, institutions of higher professional education, students of institutions of additional professional education, heads and specialists of educational institutions in the sphere of culture. Published on the recommendation of the State Scientific Institution "Siberian Scientific Center of the Russian Academy of Education".
Do que estamos falando quando falamos do valor da ciência: Reflexões a partir de Eric Weil
Authors: Castelo Branco Judikael
Published: November 2021

O artigo analisa o papel da ciência na construção da nossa cultura a partir da obra de Eric Weil, particularmente de La Science et la civilisation moderne ou le sens de l’insensé. O objetivo é iluminar questões fundamentais quer no que tange a elementos constitutivos do tema, quer em circunstâncias históricas recentes, como o atual negacionismo. Para tanto, dividimos nosso trabalho em três partes: o status quaestionis da consideração da ciência moderna; algumas observações de cunho historiográfico, e nossas considerações finais.
PLANEJAMENTO ESTRATÉGICO: O USO DA FERRAMENTA BALANCED SCORECARD COMO UMA NOVA VISÃO DE GESTÃO NA COMPANHIA PERNAMBUCANA DE SANEAMENTO
Authors: Feitoza Iellen Beatriz Alves , Ferreira Leonardo Rodrigues
Published: November 2021

Resumo: O presente trabalho versa sobre o planejamento estratégico na Companhia Pernambucana de Saneamento – COMPESA, relatando os principais problemas do uso da ferramenta Balanced Scorecard - BSC, bem como, sugerindo algumas mudanças significativas nas ações administrativas, que resultarão na melhoria dos processos – tornando assim mais eficaz o uso do instrumento no planejamento da referida empresa. Após identificação da situação problema a ser investigada, foram realizadas entrevistas no sentido de aperfeiçoar as ações operacionais e em seguida refeitos os passos do planejamento. Assim, segundo as demonstrações das ações de intervenção, serão mitigadas as imperfeições do procedimento contribuindo para uma melhor eficiência das tarefas, trazendo resultados positivos para a organização.Palavras-chave: BSC. Estratégia. Processos administrativos.Abstract: The present work intends to deal with the strategic planning in the Company Pernambucana de Saneamento – COMPESA, reporting the main problems of the use of the tool Balanced Scorecard - BSC, as well as, it has been suggested some significant changes in the administrative actions, that will result in the improvement of the processes, thus making more effective the use of the instrument in the planning of the company. After identifying the problem situation to be investigated, interviews were conducted in order to improve the operational actions and then reworked the planning steps, so, according to the demonstrations of the intervention actions, the imperfections of the procedure will be mitigated, thus contributing to a better efficiency of the tasks, bringing positive results to the organization.Keywords: BSC. Strategy. Administrative processes.
A CONSTRUÇÃO DA IDENTIDADE MASCULINA NA PÓS-MODERNIDADE: NOVAS PERSPECTIVAS A PARTIR DO FRALDÁRIO MASCULINO
Authors: Souza Estevão Trindade , Souza Ligia Claudia Gomes
Published: November 2021

Resumo: O presente trabalho busca compreender e discutir a forma como o homem cisgênero tem construído a sua identidade, na época atual, denominada pós-moderna. Para problematizar esse processo, a pesquisa utilizou-se da lei de instalação de fraldários em banheiros masculinos, como meio de uma análise do contexto contemporâneo da formação identitária masculina e de novos modos de exercício da masculinidade, buscando, assim, mostrar um novo horizonte de possibilidades. O trabalho se articula teoricamente ao conceito de liquidez proposto por Zygmunt Bauman, destacando o conceito de sociedade líquida e o modo como ela influencia esse processo de construção da identidade masculina. Para tal fim, foi realizada uma revisão da literatura que apontou que há um processo de reformulação do conceito de masculinidade em curso e o fraldário no banheiro masculino indica a possibilidade de um novo exercício do masculino ao romper com a lógica machista e patriarcal.Palavras-chave: Masculinidade. Identidade. Pós-modernidade. Bauman. Abstract: This work aims to understand and discuss how the cisgender man lives his cultural identity in the present time, named as postmodern. To discuss this process, the research used the Brazilian law of installation of baby changing facilities in male bathrooms, as means to analyze the contemporary context of male identity formation and new ways of exercising masculinity, seeking a new horizon of possibilities for this process. Using as a theorical basis for this work, the “liquid society” concept, from “liquidity” concept by Zygmunt Bauman, is used to explain how it influences the construction process of male identity. In order to do this, a literature review was carried out. This indicated that there is an ongoing process of reviewing the concept of masculinity and the baby changing room in the men’s bathroom, by breaking with sexist and patriarchal logic, suggests the possibility of a new male ways of living.Keywords: Masculinity. Identity. Postmodernity. Bauman.
Frantz Fanon e sua contribuição para o debate da Saúde Mental no Brasil
Authors: Caputo Lara Rodrigues
Published: November 2021

Resenha do livro Alienação e liberdade: Escritos psiquiátricos, de Frantz Fanon (São Paulo: Ubu, 2020)
As experiências formativas da atriz Aracy Cortes e sua qualidade mulata: o teatro de revistas como espaço de práticas educativas difusas no Rio de Janeiro dos anos 1920
Authors: Pinto Rebeca Natacha de Oliveira
Published: November 2021

A partir da trajetória de Zilda de Carvalho Espíndola (1905-1985), também conhecida como Aracy Côrtes, este trabalho se propõe a refletir sobre as desigualdades de gênero e raça na capital federal, nos anos 1920. Desta forma, suas origens, processos educativos e os espaços por onde atuou, nos permitem iluminar um caminho possível, e muitas vezes tortuoso, para a ascensão social através no universo do entretenimento. Na tentativa de articular cultura e educação, busco apreender através de suas experiências artísticas, especialmente a personagem "Mulata", um destaque na carreira dessa atriz e cantora, como os debates sobre nação, gênero e raça eram construídas nos palcos do Teatro de Revistas do Rio de Janeiro, no alvorecer do novecentos.
Nadhezda Krupskaia: ação e luta de uma educadora comunista
Authors: Silva Dagmar De Mello e , Ferreira Maria Onete Lopes , Reis Maria Cláudia
Published: November 2021

Apresentamos a trajetória político-revolucionária de Nadhezda Konstantínovna Krupskaia e suas ideias forjadas na luta pela transformação social no contexto da Russa czarista. Destacamos sua coragem ao afirmar uma educação forjada na luta política de princípios socialistas e de igualde de gênero. Para tanto, baseamos o trabalho em obras de Samantha Lodi-Corrêa que se dedicou ao estudo biográfico desta educadora revolucionária que assumiu protagonismo na Revolução Russa, junto ao marido – Lenin -, apontando sua autonomia intelectual e militante, como mulher de vanguarda. Lamentamos a ausência de uma Krupskaia no Brasil, para destacar que nós, infelizmente, demoramos muito a compreender a natureza de classe da educação.
Género y curriculum: una mirada generizada sobre el plan de estudios de la carrera de sociología
Authors: Malizia Andres
Published: November 2021

En este artículo me propongo describir y analizar el plan de estudios de la carrera de Sociología de la Universidad de Buenos Aires, Argentina. Especialmente me interesa indagar sobre las formas en que aparecen explicitadas las problemáticas y perspectivas de géneros en los programas que conforman el ciclo de la licenciatura. Teniendo en consideración que las universidades son formadoras de docentes, en este trabajo analizo las características que asumen dichas perspectivas en el plan de estudios, entendiendo que el mismo nos ofrece una version posible acerca de cómo se forman en la universidad quienes pueden ejercer la docencia en la educación secundaria y superior. La intención final es la de producir una aproximación crítica sobre la formación universitaria en géneros y sexualidades.
Representações de José Gaspar Rodríguez de Francia a partir do manual didático
Authors: Brighent Clovis Antonio
Published: November 2021

O artigo se propõe a analisar as representações de José Gaspar Rodríguez de Francia nos “manuais didáticos” de história na rede de ensino do Paraguai. O trabalho objetiva analisar a construção da sua imagem pública através das narrativas históricas em torno da sua pessoa nos manuais didáticos oficiais de história distribuídos pelo Ministério da Educação - (MEC) do Paraguai e em manuais de escolas privadas, manuais dos anos de 2005, 2010, 2016, 2017. Este trabalho se caracteriza como pesquisa qualitativa, tendo como metodologia a ser aplicada a análises em manuais didáticos de história do Paraguai, livros do ensino fundamental e médio.
Uma perspectiva arqueológica da educação de jovens e adultos no Brasil
Authors: Nascimento Rebeca Barbosa , Borges Carla Luzia
Published: November 2021

Com relevantes contribuições em diversas áreas do conhecimento, Michel Foucault trouxe, em suas obras, importantes reflexões sobre os sujeitos e seus processos de constituição histórica dentro das relações estabelecidas entre poder, verdade e saber. Partindo da noção foucaultiana de sujeito, o presente trabalho configura-se como uma investigação de processos histórico-discursivos que interpelam a formação do Sujeito Estudante do Programa de Educação de Jovens a Adultos (EJA). Para tanto, foi construído um breve panorama histórico-documental sobre os movimentos de educação para jovens e adultos no Brasil, refletindo sobre a constituição do programa em sua relação com o público para o qual ele é direcionado. Com base em A Arqueologia do Saber, trazemos, portanto, de uma leitura atenta às possíveis regularidades encontradas na materialidade linguística na Proposta Curricular da Educação de Jovens e Adultos (PCEJA). A identificação das possíveis regularidades é seguida de uma caracterização das superfícies de emergência de possíveis discursos e, posteriormente, são demarcadas as possibilidades e interdições que delimitam as margens de constituição do sujeito estudante da EJA através das exterioridades.
Governamentalidade didático-filosófica como prática de governo dos alunos: a leitura de textos filosóficos em sala de aula
Authors: Barros Igor Corrêa de
Published: November 2021

O presente artigo busca promover uma reflexão sobre a didática do ensino de filosofia a partir de um relato de experiência com o uso de textos filosóficos no ensino médio. Analisa a didática aplicada nessa experiência à luz do aparato teórico metodológico do filósofo Michel Foucault (1926 - 1984). Este trabalho é uma tentativa e um convite a utilização de conceitos foucaultianos, em especial “governo” e “governamentalidade” como ferramentas para repensar a relação entre aluno e professor. Pensar o processo educacional como forma de governo e autogoverno, ou seja, como condução das condutas, significa levar em conta as práticas, estratégias e objetivos pelos quais os indivíduos, em sua liberdade, tentam governar os outros e a si mesmos.
Por uma gestão do cuidado: problematizações acerca da gestão escolar e suas atualizações
Authors: Corrêa Mirele , Cervil Gicele Maria , Schütz Monique Cristina Francener Hammes
Published: November 2021

Discutir a escola e a gestão escolar é mover-se atento nos fluxos da sociedade de controle, entendendo como os dispositivos de regulação operam nos tempos e espaços, produzindo determinados corpos alinhados a uma certa lógica econômica. O artigo propõe problematizar a escola e a subjetividade do gestor por ela produzida. Busca fazer um exercício genealógico, localizando a invenção da escola na modernidade e atualizações na contemporaneidade. Apresenta as modulações da racionalidade empresarial para a escola, que transforma o diretor em gestor. Envereda-se a traçar possibilidades de ser gestor por meio da ideia de “cuidado de si” desenvolvida por Foucault, como alternativa ao gestor-polícia da escola atual.
Impacto de uma abordagem de dança sobre a ansiedade, estresse e depressão em universitários
Authors: Silva Josimáteus Geraldo Ataíde Rocha da , Romarco Evanize Kelli Siviero
Published: November 2021

A ansiedade, o estresse e a depressão são desordens mentais comuns que impactam negativamente a vida dos universitários. Este estudo de campo, de natureza exploratória e descritiva, possui o objetivo de analisar os níveis dessas desordens em participantes de um grupo de vivências corporais baseadas no Contato improvisação (CI). Inicialmente, foi realizado o chamamento público aos estudantes. As práticas foram realizadas duas vezes na semana durante doze semanas, com duração de 60 minutos cada encontro. Foram utilizados quatro questionários: uma ficha sociodemográfica, a PSS, o BAI, e o BDI. Os scores obtidos foram tabulados e analisados. Os dados qualitativos foram registrados a partir de material videográfico e através de um diário de bordo. A abordagem através do CI evidenciou nos voluntários melhoras em aspectos quantitativos e qualitativos sob distintas variáveis que influenciam nessas desordens.
Pedagogias em disputa: Denize Sepulveda entrevista Sara Wagner York
Authors: York Sara Wagner , Sepulveda Denize
Published: November 2021

O apresente texto desdobra formas de se fazer e falar sobre e com sujeitas implicadas com suas salas de aula e, sobretudo, com o ensino de formação de professoras e professores, mas não só, é sobre formas (in)visíveis de Educação. Ao trazermos essa entrevista, podemos de algum modo produzir nossos arquivos e até as nossas memórias que estão em constante disputa. Em 2018, a professora Sara Wagner York, afirmou em muitas de suas lives ter catalogado mais de 500 Trabalhos de Conclusão de Curso de Pedagogia, do curso de Educação a Distância – EAD da UERJ entre os anos de 2010 a 2017. Após levantamento inicial verificou se que as palavras Ludicidade, Letramento e Diversidade eram as mais presentes. Diante do levante conservador a partir do Golpe de Estado de 2016, ficou ainda mais perceptível a inserção de mulheres e homens evangélicos nos cursos de docência e principalmente nos cursos de Pedagogia. Evangélicas/os inseriam “diversidade” como palavra-chave, intencionando uma educação para todos. Um movimento similar também era produzido por jovens e adultas/os/es trans e travestis que perceberam a educação, e principalmente a Pedagogia, como instrumento fundante para mudança no cenário nacional. Esta entrevista realizada no ano pandêmico de 2021, no mês de setembro, marca um movimento cada vez mais frequente: a ocupação da diferença (marcada pelo gênero, sexualidades e identidades - e seus vários corpos) na cena educacional brasileira.
A day of skills and knowledge
Authors: Kurtkoti Rucha , Gardner Sophie
Published: November 2021

Rucha Kurtkoti and Sophie Gardner report on some of the sessions from a recent Wound Care Alliance UK skills day
Deep infection after hip hemiarthroplasty: risk factors for infection and outcome of treatments
Authors: Craxford Simon , Marson Ben A. , Nightingale Jessica , Ikram Adeel , Agrawal Yuvraj , Deakin Dan , Ollivere Benjamin
Published: November 2021

Aims

Deep surgical site infection (SSI) remains an unsolved problem after hip fracture. Debridement, antibiotic, and implant retention (DAIR) has become a mainstream treatment in elective periprosthetic joint infection; however, evidence for DAIR after infected hip hemiarthroplaty is limited.

Methods

Patients who underwent a hemiarthroplasty between March 2007 and August 2018 were reviewed. Multivariable binary logistic regression was performed to identify and adjust for risk factors for SSI, and to identify factors predicting a successful DAIR at one year.

Results

A total of 3,966 patients were identified. The overall rate of SSI was 1.7% (51 patients (1.3%) with deep SSI, and 18 (0.45%) with superficial SSI). In all, 50 patients underwent revision surgery for infection (43 with DAIR, and seven with excision arthroplasty). After adjustment for other variables, only concurrent urinary tract infection (odds ratio (OR) 2.78, 95% confidence interval (CI) 1.57 to 4.92; p < 0.001) and increasing delay to theatre for treatment of the fracture (OR 1.31 per day, 95% CI 1.12 to 1.52; p < 0.001) were predictors of developing a SSI, while a cemented arthroplasty was protective (OR 0.54, 95% CI 0.31 to 0.96; p = 0.031). In all, nine patients (20.9%) were alive at one year with a functioning hemiarthroplasty following DAIR, 20 (46.5%) required multiple surgical debridements after an initial DAIR, and 18 were converted to an excision arthroplasty due to persistent infection, with six were alive at one year. The culture of any gram-negative organism reduced success rates to 12.5% (no cases were successful with methicillin-resistant Staphylococcus aureus or Pseudomonas infection). Favourable organisms included Citrobacter and Proteus (100% cure rate). The all-cause mortality at one year after deep SSI was 55.87% versus 24.9% without deep infection.

Conclusion

Deep infection remains a devastating complication regardless of the treatment strategy employed. Success rates of DAIR are poor compared to total hip arthroplasty, and should be reserved for favourable organisms in patients able to tolerate multiple surgical procedures. Cite this article: Bone Jt Open 2021;2(11):958–965.
Crimes of a “benevolent” hegemony: Configurations of UK power in Northern Ireland and Iraq
Authors: Hamourtziadou Lily , O'Sullivan Aidan
Published: November 2021

Themes of hegemony and neoliberalism are explored in this paper that looks at UK role in crimes against humanity in Ireland and in Iraq, either alone or as part of a hegemonic coalition that claims to be fighting a brutal, unjust, and uncivilized insurgency. The common thread that ties crimes spanning 100 years is the narrative of the “benevolent” hegemon that kills, tortures, enslaves, and occupies for the good of the victims. Power is exercised by the hegemon through military and political domination under the guise of a civilized protector, liberator, and the bearer of progress and order.
Michael Collins: Founder of modern guerrilla warfare tactics
Authors: Lynch Matthew
Published: November 2021

This paper examines the foundations of contemporary guerrilla warfare tactics and associates these with the actions and operations of General Michael Collins and the Irish Volunteers throughout the War of Independence (1919–21). Through the critical analysis of archival documents from the War of Independence provided by the Irish Military Archives, the paper analyses the success and nature of these tactics in relation to the fundamental characteristics that are observed within guerrilla warfare. The paper draws comparisons with Vietnam (1955–75), Iraq (2003–11), and Afghanistan (2001–21), in the context of war against a strong hegemonic power.
An agent based force vector model of social influence that predicts strong polarization in a connected world
Authors: Maclay G. Jordan , Ahmad Moody
Published: November 2021

The model is based on a vector representation of each agent. The components of the vector are the key continuous “attributes” that determine the social behavior of the agent. A simple mathematical force vector model is used to predict the effect of each agent on all other agents. The force law used is motivated by gravitational force laws and electrical force laws for dipoles. It assumes that the force between two agents is proportional to the “similarity of attributes”, which is implemented mathematically as the dot product of the vectors representing the attributes of the agents, and the force goes as the inverse square of the difference in attributes, which is expressed as the Euclidean distance in attribute space between the two vectors. The force between the agents may be positive (attractive), zero, or negative (repulsive) depending on whether the angle between the corresponding vectors is less than, equal to, or greater than 90°. A positive force causes the attributes of the agents to become more similar and the corresponding vectors to become more nearly parallel. Interaction between all agents is allowed unless the distance between the attributes representing the agents exceeds a confidence limit (the Attribute Influence Bound) set in the simulation. Agents with similar attributes tend to form groups. For small values of the Attribute Influence Bound, numerous groups remain scattered throughout attribute space at the end of a simulation. As the Attribute Influence Bound is increased, and agents with increasingly different attributes can communicate, fewer groups remain at the end, and the remaining groups have increasingly different characteristic attributes and approximately equal sizes. With a large Attribute Influence Bound all agents are connected and extreme bi- or tri-polarization results. During the simulations, depending on the initial conditions, collective behaviors of grouping, consensus, fragmentation and polarization are observed as well as certain symmetries specific to the model, for example, the average of the attributes for all agents does not change significantly during a simulation.
Performing #MeToo: How Not to Look Away
Authors: Rudakoff Judith
Published: November 2021

Voices from diverse cultural and environmental contexts writing on forms of engagement with the topic of performing #MeToo - testimony, witnessing, interpretation, field reports. Includes people who speak from personal experience, as well as allies, activists, and scholars. Examines contemporary work, and work from the pre-#MeToo era.
GATES/GEB as the Best Thermodynamic Approach to Electrolytic Redox Systems - a Review
Authors: Michałowska-Kaczmarczyk Anna M. , Michałowski Tadeusz
Published: November 2021

The Generalized Approach To Electrolytic Systems (GATES) provides the best possible thermodynamic formulation of redox and non-redox, equilibrium and metastable, mono-, two- and three-phase systems, with all attainable/pre-selected physicochemical knowledge involved, without any simplifying assumptions made for calculation purposes, where different species may occur in batch or dynamic systems, of any degree of complexity. The Generalized Electron Balance (GEB) is the key concept completing the set of algebraic balances referred to redox systems, described according to GATES/GEB ⊂ GATES principles. The GEB, considered as the law of Nature, is fully compatible with charge and concentration balances, and relations for the corresponding equilibrium constants. Within GATES, the electrolytic systems are resolvable with use of MATLAB, or other iterative computer programs, if all necessary physicochemical knowledge is attainable.
Whose Sidewalk?
Authors: Kouros Theodoros
Published: November 2021

Home is a nodal point in a series of polarities, including family-community; space-place; inside-outside; private-public; domestic-social. These may not be stable but seem both solidified and undermined as they play out their meaning and practice in and through the home. The “public” is traditionally the state’s domain, while the “private” the citizens’. But where does “private” end and “public” begin? Can a border or boundary be placed between the two? Is such a boundary culture-specific or universal? Is it static or dynamic? Scholars often perceive borders as barriers and bridges, porous and impenetrable, and border studies have shown that urban entities have their own internal and external borders. I argue that such internal urban micro-boundaries can be found in the domain of domestic space, separating the private from the public, and that they are dynamic and constantly negotiated. Not necessarily marked, they are acknowledged by a mutual and tacit agreement, a social and cultural consensus. In this paper, I focus on common expansions of private into public space in Limassol, Cyprus, and the ways in which, this social consensus is achieved through the use of several tactics. As I illustrate, all these tactics seem to transform public space into private, on a symbolic level. The paper’s contribution lies in the examination of this type of boundary, which has received little academic attention, as well as in the introduction of the term “tactics of inhibition.”
Gene Therapy for Huntington’s Disease: The Final Strategy for a Cure?
Authors: Byun Seulgi , Lee Mijung , Kim Manho
Published: November 2021

Huntington’s disease (HD) has become a target of the first clinical trials for gene therapy among movement disorders with a genetic origin. More than 100 clinical trials regarding HD have been tried, but all failed, although there were some improvements limited to symptomatic support. Compared to other neurogenetic disorders, HD is known to have a single genetic target. Thus, this is an advantage and its cure is more feasible than any other movement disorder with heterogeneous genetic causes. In this review paper, the authors attempt to cover the characteristics of HD itself while providing an overview of the gene transfer methods currently being researched, and will introduce an experimental trial with a preclinical model of HD followed by an update on the ongoing clinical trials for patients with HD.
Association of AXIN1 With Parkinson’s Disease in a Taiwanese Population
Authors: Fang Hwa-Shin , Chao Chih-Ying , Wang Chun-Chieh , Fan Wen-Lang , Huang Po-Jung , Fung Hon-Chung , Wu Yih-Ru
Published: November 2021

Objective A meta-analysis of locus-based genome-wide association studies recently identified a relationship between AXIN1 and Parkinson’s disease (PD). Few studies of Asian populations, however, have reported such a genetic association. The influences of rs13337493, rs758033, and rs2361988, three PD-associated genetic variants of AXIN1, were investigated in the present study because AXIN1 is related to Wnt/β-catenin signaling.Methods A total of 2,418 individuals were enrolled in our Taiwanese cohort for analysis of the genotypic and allelic frequency. Polymerase chain reaction–restriction fragment length polymorphism analysis was employed for rs13337493 genotyping, and the Agena MassARRAY platform (Agena Bioscience, San Diego, CA, USA) was used for rs758033 and rs2361988 genotyping in 672 patients with PD and 392 controls. Taiwan Biobank data of another 1,354 healthy controls were subjected to whole-genome sequencing performed using Illumina platforms at approximately 30× average depth.Results Our results revealed that rs758033 {odds ratios [OR] (95% confidence interval [CI]) = 0.267 [0.064, 0.795], p = 0.014} was associated with the risk of PD, and there was a trend toward a protective effect of rs2361988 (OR [95% CI] = 0.296 [0.071, 0.884], p = 0.026) under the recessive model. The TT genotype of rs758033 (OR [95% CI] = 0.271 [0.065, 0.805], p = 0.015) and the CC genotype of rs2361988 (OR [95% CI] = 0.305 [0.073, 0.913], p = 0.031) were less common in the PD group than in the non-PD group.Conclusion Our findings indicate that the rs758033 and rs2361988 polymorphisms of AXIN1 may affect the risk of PD in the Taiwanese population.
The Work of Craterus and the Documents in the Attic Orators and in the “Lives of the Ten Orators”
Authors: Harris Edward
Published: November 2021

This essay is divided into three parts. The first examines the documents about Antiphon in the “Lives of the Ten Orators” (Plut. X orat. 833d–834b), which have been attributed to the collection of Craterus, and shows that they must be forgeries because the information contained in them is inconsistent with reliable sources about Athenian laws and legal procedure and with the language and formulas of the preserved decrees of the fifth century and contains other serious mistakes. The second section examines the fragments of the work of Craterus and shows that all are Athenian decrees, most of which relate to imperial administration or to famous personalities and are dated to the period between roughly 480 and 410. None of the fragments of this work can be dated earlier or later than this period. The third section reviews the documents inserted into the texts of the speeches of Andocides, Aeschines and Demosthenes and shows that in the majority of cases the editors who inserted these documents into the text could not have used the work of Craterus either for the texts of the genuine documents or for the information contained in the forged documents. In the other cases there is no evidence indicating that these editors consulted his work, and it appears that those who composed these documents used other sources.
Para una zoología de la realeza: Alejandro Magno y los elefantes
Authors: Alonso Troncoso Victor
Published: November 2021

Este artículo estudia la relación de Alejandro Magno con los elefantes, tanto desde el punto de vista militar como simbólico. Opera con el concepto de zoología de la realeza, analizando el status y jerarquía de caballos, águilas, leones, elefantes y dromedarios en la nueva ideología del conquistador macedonio.
Dissecting role of founder mutation p.V727M in GNE in Indian HIBM cohort
Authors: Attri Shivangi , Sharma Vikas , Kumar Amit , Verma Chaitenya , Gahlawat Suresh Kumar
Published: November 2021

GNE gene-specific c.2179G>A(p.V727M) is a key alteration reported in patients with hereditary inclusion body myopathy (HIBM) and represents an ethnic founder mutation in the Indian cohort. However, the underlying role of this mutation in pathogenesis remains largely unknown. Thus, in this study, we aimed to access possible mechanisms of V727M mutation that could be leading to myopathy. We evaluated various in silico tools to predict the effect of this mutation on pathogenicity, structural or possible interactions, that could induce myopathy. Our results propose that V727M mutation could induce deleterious effects or pathogenicity and affect the stability of GNE protein. Analysis of differential genes reported in the V727 mutant case suggests that it can affect GNE protein interaction with Myc-proto-oncogene (MYC) transcription factor. Our in silico analysis also suggests a possible interaction between GNE ManNac-kinase domain with MYC protein at the C-terminal DNA-binding domain. MYC targets reported in skeletal muscles via ChIP-seq suggest that it plays a key role in regulating the expression of many genes reported differentially expressed in V727M-mutated HIBMs. We conclude that V727M mutation could alter the interaction of GNE with MYC thereby altering transcription of sialyltransferase and neuromuscular genes, thus understanding these effects could pave the way for developing effective therapies against HIBM.
Visualization of Prior Austenite Grain Boundaries in Low-Carbon Steels
Authors: Böcker M. , Steinbacher M. , Fechte-Heinen R.
Published: November 2021

Knowledge of the size of the prior austenite grain is of key importance. If abnormal grain growth occurs during austenitization, the resultant inhomogeneous microstructure may negatively affect the strength and toughness properties of the final product. The visualization of prior austenite grain boundaries with an etchant based on picric acid has been applied for years. Despite this long-time experience, it is often challenging to achieve sufficiently good visualization of prior austenite grain boundaries in many steel grades, especially low-carbon steels. This work will study the effect of the cooling rate from austenitizing temperature down to room temperature, of the subsequent tempering treatment and the etchant on the visualization of prior austenite grain boundaries in a low-carbon microalloyed steel. All these parameters have an impact on the etching result. A suitable etchant for the visualization of prior austenite grain boundaries in a low-carbon microalloyed steel could be found.