Chemical composition, anti-inflammatory and anticholinesterase activities of the essential oils of Elionurus platypus (Trin.) Hack. from Congo
Authors:   Multidisciplinary Food and Nutrition Research Team (EPRAN), Faculty of Science and Technology, Marien Ngouabi University, Brazzaville BP 389, Congo., Bikindou Kévin ,   Department of Chemical Sciences, National Institute for Research in Exact and Natural Sciences (IRSEN), UR Chemistry of Natural Substances, Cité Scientifique, Brazzaville BP 2400, Congo.,   Plant Extracts Study Laboratory, Superior Normal School, Marien Ngouabi University, Brazzaville BP 69, Congo., Bounkosso Houzel-Mampouty ,   Multidisciplinary Food and Nutrition Research Team (EPRAN), Faculty of Science and Technology, Marien Ngouabi University, Brazzaville BP 389, Congo.,   Department of Chemical Sciences, National Institute for Research in Exact and Natural Sciences (IRSEN), UR Chemistry of Natural Substances, Cité Scientifique, Brazzaville BP 2400, Congo.,   Plant Extracts Study Laboratory, Superior Normal School, Marien Ngouabi University, Brazzaville BP 69, Congo., Boungou-Tsona Ghislaine ,   Multidisciplinary Food and Nutrition Research Team (EPRAN), Faculty of Science and Technology, Marien Ngouabi University, Brazzaville BP 389, Congo.,   Department of Chemical Sciences, National Institute for Research in Exact and Natural Sciences (IRSEN), UR Chemistry of Natural Substances, Cité Scientifique, Brazzaville BP 2400, Congo.,   Plant Extracts Study Laboratory, Superior Normal School, Marien Ngouabi University, Brazzaville BP 69, Congo., Bitemou Ernest ,   Multidisciplinary Food and Nutrition Research Team (EPRAN), Faculty of Science and Technology, Marien Ngouabi University, Brazzaville BP 389, Congo.,   Department of Chemical Sciences, National Institute for Research in Exact and Natural Sciences (IRSEN), UR Chemistry of Natural Substances, Cité Scientifique, Brazzaville BP 2400, Congo.,   Plant Extracts Study Laboratory, Superior Normal School, Marien Ngouabi University, Brazzaville BP 69, Congo., Figuérédo Gilles ,   Plant Extracts and Flavors Analysis Laboratory (LEXVA), Biopôle, Clermont-Limagne, Saint-Beauzire, France., Fauconnier Marie-Laure ,   Laboratory of Chemistry of Natural Molecules, Gembloux Agro-Bio Tech, University of Liège, Passage des Déportés 2, B-5030 Gembloux, Belgium., Chalard Pierre ,   Institut de Chimie de Clermont-Ferrand, Université Clermont Auvergne, Clermont Auvergne INP, Centre National de la Recherche Scientifique, F-63000 Clermont-Ferrand, France., Loumouamou Aubin Nestor ,   Multidisciplinary Food and Nutrition Research Team (EPRAN), Faculty of Science and Technology, Marien Ngouabi University, Brazzaville BP 389, Congo.,   Department of Chemical Sciences, National Institute for Research in Exact and Natural Sciences (IRSEN), UR Chemistry of Natural Substances, Cité Scientifique, Brazzaville BP 2400, Congo.,   Plant Extracts Study Laboratory, Superior Normal School, Marien Ngouabi University, Brazzaville BP 69, Congo.
Published: January 2024

This study reports the chemical composition, anti-inflammatory and anticholinesterase activities of the essential oils of Elionurus platypus (Trin.) Hack. The plant organs studied were the flowers (EOF), leaves (EOL), rhizomes (EORh) and roots (EOR). The essential oils were obtained by steam distillation. The chemical composition was determined using GC-MS and GC-FID. The anti-inflammatory activity was evaluated by lipoxygenase inhibition method and bovine serum albumin degradation inhibition method. The anticholinesterase activity was determined by Ellman’s method. Twenty nine compounds were identified in the essential oils of different organs, with the main one being antsorenone. The content of this compound varied from one organ to another: leaves (58.51%), rhizomes (54.98%), roots (39.90%) and flowers (32.62%). Other compounds were also identified such as myrcene (28.97%) and prezizaene (5.35%) in the EOF; camphene (4.11%) and -acorenone (4.31%) in the EOR; prezizaene (5.10%) and -acorenone (4.24%) in the EORh; epiprezizaene (4.03%) and acorenone B (2.95%) in the EOL. The anti-inflammatory activity of the essential oils of the flowers (IC50 =15.46 ± 0.54 -16.40 ± 0.47 µg/mL) and leaves (IC50 = 15.78 ± 0.57- 16.41 ± 0.46µg/mL) was high. The essential oil anticholinesterase activity of the root with an IC50 = 18.06 ± 1.85µg/mL exhibited the best inhibition. Keywords: Elionurus platypus (Trin.) Hack, essential oil, antsorenone, antiinflammatory and anticholinesterase activities.