bluuebunny/crossref_metadata_2025 huggingface dataset:
El rol de la IA en la educación a distancia: retos y oportunidades
Authors: Haro Cedeño Elizabeth Leopoldina , Beltran Illapa Carmita Cecilia , Holger Jacinto Jaramillo Jaramillo , Aguagallo Guarango Carlota Isabel , Quinchimbla Asipuela Katherin Adriana , Ruiz Avila Marcelo Miguel , Amaya Lozano Vanessa De Monserrate
Published: February 2025

El artículo denominado "El rol de la Inteligencia Artificial en la educación a distancia: desafíos y oportunidades" examina la manera en que la Inteligencia Artificial (IA) está revolucionando los procesos de enseñanza y aprendizaje en contextos de educación a distancia. En un escenario donde la pandemia de COVID-19 ha precipitado la adopción de plataformas virtuales, la Inteligencia Arti-ficial se ha consolidado como un instrumento esencial para la personalización del aprendizaje, la mejora de la interacción entre docentes y alumnos, y la optimización de los procesos administrati-vos. El propósito de este estudio es examinar los desafíos y oportunidades que emergen de la im-plementación de la Inteligencia Artificial en la educación a distancia, proporcionando enfoques desde la práctica educativa y el progreso tecnológico. La investigación adoptó una metodología mixta, con análisis cuantitativo fundamentado en datos recabados de 200 alumnos y 50 educadores que interactuaron con plataformas educativas dotadas de Inteligencia Artificial, tales como sistemas de tutoría inteligente y chatbots. Simultáneamente, se llevaron a cabo entrevistas cualitativas para indagar en las percepciones respecto a su influencia en la pedagogía. Los hallazgos sugieren que la Inteligencia Artificial tiene la capacidad de proporcionar soluciones adaptadas para cumplir con las necesidades de aprendizaje individuales, tales como la identificación precoz de estudiantes en si-tuación de riesgo, la creación de itinerarios de aprendizaje adaptativos y la automatización de la retroalimentación en tareas académicas. No obstante, también se detectaron retos significativos, entre los que se incluyen la ausencia de formación pedagógica en la utilización de herramientas de Inteligencia Artificial, la desigualdad en el acceso a tecnología de vanguardia y cuestiones éticas vinculadas a la protección de la privacidad de los datos. Estos desafíos restringen el alcance y la eficacia de la Inteligencia Artificial en contextos educativos heterogéneos. Las oportunidades abar-can la optimización de la equidad educativa a través de la implementación de recursos que se ajus-tan a variados ritmos de aprendizaje y estilos cognitivos, además de la optimización del tiempo do-cente, posibilitando un enfoque más estratégico en la atención personalizada a los alumnos. El do-cumento concluye que, aunque la Inteligencia Artificial constituye un cambio paradigmático en la educación a distancia, su implementación demanda políticas inclusivas, formación continua de los docentes y un robusto marco ético. Se aconseja llevar a cabo investigaciones adicionales sobre la incorporación de la Inteligencia Artificial en diversos sistemas educativos, con el objetivo de opti-mizar su impacto y asegurar su viabilidad a largo plazo.
Análisis socioeconómico de la producción de cebolla blanca y papa en la parroquia Santa Fe de Galán, cantón Guano, provincia de Chimborazo
Authors: Cabrera Bravo Daniel Antonio , Álvarez Sanchez Ana Ruth , Arroyo Barragán Andrea Paola , Monge Freile Marlon Fernando
Published: February 2025

En Ecuador se cultivan y comercializan diferentes variedades de cebolla y papa, lo que los convierte en cultivos andinos de mayor relevancia en la soberanía alimentaria del país, aportando la cebolla un 0.2% y la papa el 0.3 % al VAB (Valor agregado bruto) Agropecuario real. El objetivo de esta investigación fue analizar socioeconómicamente la producción de cebolla blanca y papa, y su incidencia en la Parroquia de Santa Fe de Galán, Cantón Guano, Provincia de Chimborazo, con la finalidad de proponer alternativas de mejoras en los procesos de producción y comercialización de la cebolla blanca y la papa para su desarrollo socioeconómico. En este contexto se levantó una línea base de producción, se cuantifico la producción de la cebolla blanca y la papa, se identificó la situación socioeconómica a través de un análisis y se estableció la incidencia de la producción en el desarrollo socioeconómico de la parroquia. Los resultados arrojaron que el costo de producción total de la papa dentro del área designada a la siembra que representa 10.01 hectáreas, es de $663,5 por ciclo productivo, siendo el promedio de rendimiento total de producción de 81 qq por ciclo productivo. Teniendo un precio de venta promedio del quintal de papa de $10,27, lo que genera un ingreso promedio de $170,9.El costo de producción de la cebolla blanca dentro del área designada a la siembra que representa 52.82 hectáreas, es de $6463,8 por ciclo productivo, siendo el promedio de rendimiento total de producción de 8224 atados por ciclo productivo. Teniendo un precio promedio de venta de atados de cebolla blanca de $0,98, lo que genera un ingreso promedio total de $1634,7.Esta investigación propone promover la agricultura familiar agroecológica que garantice la seguridad alimentaria de las familias en las comunidades de la parroquia Santa Fe de Galan, a través de la diversificación y manejo agroecológico de cultivos.
El uso de las TICs como estrategia pedagógica en la inclusión educativa en estudiantes de Educación Superior
Authors: Jaramillo Toledo Rosalia Yomaira , Cárdenas Santín Maria Fernanda , Cárdenas Palacios Maria Soledad , Valdivieso Guerrero Tania Salomé , Ortiz Guevara María Fernadad
Published: February 2025

Las TICs se han convertido en una herramienta escencial en el entorno educativo principalmente en la inclusión. La investigación tiene como objetico de describir las TICs en la implementación de estrategias pedagógicas que favorezcan la educación inclusiva en estudiantes de la carrera de Psicopedagogía de la Unidad de Estudios a Distancia de la Universidad Nacional de Loja. Respecto al marco metodológio cuantitativo, descriptivo, bajo un corte trasnversal con una muestra por conglomerado de 63 esudiantes y 10 docentes pertenecientes de educación superior. En lo que se pudo percibir que de parte de los educatores y educandos las TICs son una parte elemental de la educación. Abriendo puertas a la innovación y crecimiento en la educación de alto nivel.
The karyotype of Artona (Fuscartona) martini Efetov, 1997 (Lepidoptera: Zygaenidae, Procridinae, Artonini)
Authors: Efetov Konstantin A. , Parshkova Ekaterina V. , Tarmann Gerhard M.
Published: February 2025

After the last revision of Procridinae (Efetov & Tarmann 2024b) this subfamily consists of five tribes: Thyrassiini, Pollanisini, Artonini, Cleleini, and Procridini. Hitherto, the karyotypes were known only for Pollanisini and Procridini. This paper presents information about the haploid chromosome number (n = 31) that is determined for the first time for a representative of the tribe Artonini, viz. Artona martini Efetov, 1997. The previous information on ‘Artonini’ (Efetov et al. 2015) refers to Pollanisus commoni Tarmann, 2004, which is now a species of the tribe Pollanisini.
The frequency of pregnancy-associated breast diseases: a prospective cross sectional study
Authors:   Obstetrician and Gynecologist, Basrah Teaching Hospital, Basrah, Iraq, Kadhum Maysaa J. , Abbas Shaymaa F. ,   Department of Pharmacology, College of Medicine, University of Basrah, Basrah, Iraq, Abdulnabi Hamsa Sh. ,   Department of Pediatrics, Basrah Teaching Hospital, Basrah, Iraq, Baqir Qais K. ,   Department of Surgery, College of Medicine, University of Basrah, Basrah, Iraq
Published: February 2025

Background. Breast masses are common findings that observed during pregnancy, lactation or within one year after giving birth. The breast is a hormone-sensitive organ that subjects to various changes in response to hormonal changes. This study targets to identify the various types of breast masses, including benign and malignant lesions that may arise during pregnancy. Patients and methods. This is a prospective cross-sectional study conducted between June 2022 and December 2023 and enrolled 200 women who presented with breast lumps during pregnancy. All women were subjected to a thorough physical examination and investigations, including full blood picture, erythrocyte sedimentation rate, and CA15-3 tumor marker. To confirm the diagnosis, all women had ultrasound examinations and Fine Needle Aspiration Cytology (FNAC). Those with suspicion of malignancy underwent ultrasound-guided biopsy. Results. The range of ages of participants were extend from 19 to 50 years with a range gestational age of 12 to 40 weeks. Our results showed that the highest percentage of women presented with breast lesions was in the age group of 19-30 years (about 57.5% of cases), while in the age groups of (31-40 and 41-50) years, the percentage of affected pregnant women were 28% and 14.5%, respectively. Moreover, the final diagnosis of various breast lesions predominantly revealed benign breast masses, in approximately 98% of cases. Out of the total patients, 81 (40.5%) were diagnosed with fibroadenomas, which are the most prevalent benign breast masses. Next, lactating adenomas, which affected up to 25% of women, followed by galactoceles, which were discovered in 22% of women, along with papillomas, which identified in 21 women (10.5% of the total). Breast cancer, on the other hand, had the lowest prevalence among the pregnant women compared to benign breast lesions, where only five cases were reported (about 2% of all cases). Conclusions. The breast cancer was discovered in only 2% of cases, while the majority of the breast lumps, which observed during pregnancy, were benign with fibroadenoma being the most common entity, following by lactating adenoma, galactocele and finally papilloma.
Computational profiling of antidepressants-induced molecular docking with placental proteins (IGFBP-1, PlGF-1 and GATA3)
Authors:   Science Department, College of Basic Education, Misan University, Misan, Iraq, Al-Saray Sarah T. , Hussein Baydaa A. ,   Science Department, College of Basic Education, Misan University, Misan, Iraq, Dhabian Saja Z. ,   Science Department, College of Basic Education, Misan University, Misan, Iraq, Al-Ali Ali A. ,   Biology Department, College of Education for Pure Science, Basrah University, Basrah, Iraq, Hashim Hayder O. ,   Department of Clinical Laboratory Sciences, College of Pharmacy, University of Babylon, Babylon, Iraq, Mohammed Mudher K. ,   Department of Pharmacy, Al-Manara College of Medical Science, Misan, Iraq
Published: February 2025

Background. Antidepressants readily penetrate the intrauterine environment, potentially influencing the genetic expression of specific genes in the fetal portion of the placenta. Nevertheless, there is a lack of understanding regarding the precise impact of these medications on placental proteins, which play critical roles in embryonic development. Methods. Therefore, investigating their interaction with placental proteins is crucial. Utilizing computa­tional analysis and molecular docking software, this study explores the interactions between ten antidepressant medications and the proteins IGFBP-1, PlGF-1, and GATA3 through dynamic simulation. Results. The findings from molecular docking reveal a clear inclination of all drugs to bind with these proteins, albeit with varying degrees of affinity. Certain drugs (Trazodone, Amitriptyline, Nortriptyline, and Mirtazapine) exhibit high affinities for these proteins, while others show lower affinities (Desvenlafaxine, Phenelzine, and Tranylcypromine). The affinity values for IGFBP-1 and PlGF-1 ranged from -6.8 to -3.9 kcal/mol, with an average of -5.9 kcal/mol. In comparison, the affinity range for the GATA3 protein was -7.8 to -5.1 kcal/mol. Conclusion. The molecular dynamics simulation of the four drugs with high affinity to proteins revealed that, except for Trazodone, they did not maintain stability within acceptable limits. Interestingly, Trazodone showed signs of stability with the IGFBP-1 protein throughout the molecular dynamics simulation. These findings may indicate that Trazodone potentially influences embryonic development, raising safety concerns for maternal-fetal health. Choosing the safest antidepressants requires balancing their mental health benefits with their potential molecular effects on placental proteins, ensuring the well-being of both mother and fetus during pregnancy. Further research and clinical guidelines should explore the interplay between antidepressant affinities and maternal-fetal health outcomes for a more informed approach to perinatal mental health care.
Need Analysis for Developing a Problem-Based Learning E-Module in Mathematics with Integrated Global Citizenship Education
Authors: Devi Subramaniam Vimala , Rajoo Murugan
Published: February 2025

Global Citizenship Education is a framework designed to cultivate responsible citizens who respect values such as justice and equality, ultimately contributing to a more peaceful and sustainable world. By exposing primary school students to global issues, they can better understand critical challenges, particularly the eradication of global poverty, climate change, and peace, which can help them become more engaged global citizens. However, aspects of Global Citizenship Education are often overlooked in primary mathematics education. This study aims to evaluate mathematics teachers' perceptions of implementing a problem-based learning e-module that incorporates Global Citizenship Education into the topic of Data Handling. Additionally, it seeks to gauge the respondents’ agreement on integrating Global Citizenship Education (GCED) into the mathematics teaching and learning process. An online questionnaire (Google Form) was administered to 52 primary school mathematics teachers from the state of Negeri Sembilan. The findings indicate that 40% of the respondents were unfamiliar with Global Citizenship Education, and 70% had never incorporated it into their mathematics teaching. Nevertheless, 80% of the teachers agreed that integrating Global Citizenship Education themes into mathematics classrooms would enhance students’ global awareness and motivate them to learn mathematics. Furthermore, the study found that the Problem-Based Learning approach allows students to acquire new knowledge about real-world mathematical problems. In conclusion, there is a clear need to develop a problem-based learning e-module in mathematics that integrates Global Citizenship Education.
Promises and Pitfalls of Metal Oxide Nanoparticles for Water Purification: A Sustainable Innovation or a Hidden Hazard?
Authors: Ayah Tariq Abdulsalam Omer  , Amani Al-Othman  , Chun Kit Ang  , Ching Yin Ng  , Vienglasy Mangnomek  , Swee Pin Yeap
Published: February 2025

Water, an indispensable resource in sustaining life, necessitates pursuing optimal purification processes amidst the rising concern of water insecurity. Technological advancements, particularly through integrating nanomaterials into separation technology, have made a significant leap in the area of water purification. This paper focuses on the application of metal oxide nanoparticles (MONPs) in separation technologies, and their incorporation into nano-infused nets (NINs), which showed significant enhancement to the filtration efficiency. While NINs hold significant promise for water solutions, concerns about potential environmental impact and health risks require further investigation and careful consideration. This opinion paper explores the benefits, challenges, public concerns and ethical considerations surrounding the use of MONPs in water purification, emphasising the need for responsible implementation and international regulations that facilitate their sustainable and ethical use in water purification.
العلاقة بين رأس المال الفكري واتعاب التدقيق : دراسة استطلاعية لآراء عينة من المدققين العاملين في شركات ومكاتب التدقيق الخارجي
Authors: ظاهر وسام
Published: February 2025

تهدف هذه الدراسة للبحث في ما إذا كان رأس المال الفكري المتمثل بأبعاده الثلاثة (رأس المال البشري، رأس المال الهيكلي ورأس مال العلائقي) مرتبطاً بأتعاب التدقيق في مكاتب وشركات التدقيق الخارجي، فقد اعتمدت الدراسة على استخدام المنهج الوصفي التحليلي، حيث يتكون مجتمع الدراسة من العاملين في شركات ومكاتب التدقيق الخارجي، إذ بلغ عدد أفراد عينة الدراسة 39 فرداً، وهم الذين قاموا بالإجابة على اسئلة استمارة الاستبانة، تم اختبار الفرضية باستخدام الانحدار المتعدد، وأظهرت النتائج أن رأس المال الفكري يرتبط بشكل إيجابي ومعنوي بأتعاب التدقيق. لهذا يمكن اعتبار مستوى الاستثمار الفعال في الرأس المال الفكري وابعاده عاملاً رئيسياً من المتوقع أن تأخذه المكاتب والشركات في الاعتبار. وتوفر نتائج هذا الدراسة آثاراً قيمة لمستخدمي البيانات المالية والمحللين وواضعي السياسات بمعلومات تتعلق بالرأس المال الفكري وأبعاده وأتعاب التدقيق.
التمكين النفسي وأثره في النية السلوكية لاستخدام تقانة الواقع المعزز للوعي بالأمن السيبراني: دراسة مسحية في القطاع المصرفي
Authors: الشاهر علي , جاسم طالب
Published: February 2025

يهدف البحث لدراسة آثر التمكين النفسي في تبني تقانة الواقع المعزز للأفراد العاملين في القطاع المصرفي للوعي بالأمن السيبراني، وبما أن أغلب المنظمات تتطلب التعامل مع الأعمال باستخدام تقانات حديثة كتقانة الواقع المعزز، للحد من الهجمات السيبرانية، اعتمد البحث نهجاً وصفياً عن طريق استمارة استبيان وتم الحصول على (303) إجابة من الأفراد العاملين في القطاع المصرفي الحكومي والأهلي للمنطقة الشمالية (موصل – كركوك- تكريت)، وباستخدام البرمجة الإحصائية (SPSS)حيث توصل البحث إلى أن التمكين النفسي له دور إيجابي في تبني تقانة الواقع المعزز للوعي بالأمن السيبراني.
تأثير حوكمة الموارد البشرية في تعزيز المرونة التنظيمية: دراسة وصفية تحليلية لآراء عينة من الموظفين في مديرية الإحصاء في محافظة صلاح الدين
Authors: حاجم ياسر , شران هبة , ابراهيم مثنى
Published: February 2025

تمثل هدف البحث في بيان مدى الأثر الذي تسهم به (حوكمة الموارد البشرية) في تعزيز (المرونة التنظيمية) في مديرية الإحصاء في محافظة صلاح الدين، وكان مجتمع البحث يتمثل بالعاملين بصفة (إدارية وتقنية) في مديرية الإحصاء في صلاح الدين الذين تم استهدافهم من خلال عينة قصدية شملت (52) فردأ من مجتمع البحث البالغ (60) فرداً، وصل للباحثون فعلياً منها (45) استمارة، وتم استبعاد (3) منها لعدم صلاحيتها، بالتالي أصبح عدد الاستمارات (42) استمارة جاهزة للتحليل الإحصائي، وبهدف معالجة البيانات استعملت العديد من الاساليب الإحصائية منها(الاوساط الحسابية، الانحراف المعياري، معامل الاختلاف، معامل الارتباط R ، معامل التأثير R2 ، ومعاملB ، وقيمة F & t ، ومستوى الدلالة المعنوية) بالاعتماد على البرنامج الإحصائي(SPSS V.20)، توصل البحث الى عدة استنتاجات من اهمها وجود أثر ذو دلالة إحصائية لـ(حوكمة الموارد البشرية) وابعادها الفرعية في تعزيز (المرونة التنظيمية).
تحليل واقع المشروعات الريادية الصغيرة على المؤشر الاقتصادي في العراق للمدة (2004-2021)
Authors: عواد خالد , ودود سفيان
Published: February 2025

يهدف البحث الى بيان تحليل واقع المشروعات الريادية الصغيرة على المؤشر الاقتصادي في العراق للمدة (2004-2021) من اجل الوقوف على اهم المعوقات التي تقف بوجه هذه المشروعات لمعرفة الدور الذي من الممكن ان تؤديه المشروعات الريادية الصغيرة في تحقيق التنمية الاقتصادية من خلال معرفة العلاقة بين متغيرات البحث خلال المدة المدروسة، لان المشروعات الريادية الصغيرة تمثل الركيزة الأساسية لمعظم الاقتصادات كونها تسهم في معالجة الاختلالات وبالتالي تحقيق التنمية الاقتصادية، أذ تمثل المشروعات الريادية احد اهم المظلات الساندة لاقتصادات مختلف البلدان لاسيما العراق الذي يتسم بانتشار مشاكل مفصلية تعيق النمو الاقتصادي في مختلف القطاعات.
انموذج مقترح لقياس جودة التدقيق في البيئة العراقية
وفقاً لإصدارات IAASB)&PCAOB)
Authors: الطائي اوس , محمد عبدالواحد , زكر ضحى
Published: February 2025

يهدف البحث الى اقتراح مؤشرات خاصة لقياس جودة التدقيق وذلك بالاعتماد على الإصدارات الدولية وخاصة إصدارات مجلس معايير التدقيق والتأكيد الدولية IAASB واصدارات مجلس الاشراف على محاسبة الشركات العامة PCAOB، وتم صياغة هذه المؤشرات بما يتناسب مع البيئة العراقية وذلك من خلال الاعتماد على اراء المدققين (العاملين في القطاع الخاص والحكومي) والاكاديميين الاختصاص في المحـاسبة والتدقيق (من خـلال المقابلات الشـخصية للمدققين في مكاتب التدقيق العراقية وديوان الرقابة المالية الاتحادي)، بالإضافة الى استمارة الفحص التي حاولت قياس مدى توفر مؤشرات جودة التدقيق في البيئة العراقية.
قياس فاعلية السياسة الانفاقية للحد من معدل التضخم في العراق للمدة (2004-2021)
Authors: عواد خالد روكان عواد , لهمود فكري
Published: February 2025

ان فاعلية السياسة الانفاقية تحتل أهمية كبيرة في الدراسات الاقتصادية، لذلك تعد الأداة الأهم والاكبر التي تستخدمها الدولة وذلك من اجل تحقيق التقدم في كافة المجالات الاقتصادية والمالية، وبذلك يمكن القول ان السياسة الانفاقية تعكس الصورة الكبيرة المرسومة للأهداف الدولة، التي تسعى دائماً لنهوض بالواقع الاقتصاد الوطني، وذلك من اجل دفع عملية التنمية والاستقرار الاقتصادي داخل الدولة، وذلك نجد ان من الضرورة تدخل الدولة احياناً في الاقتصاد وذلك من اجل خفض المستوى العام للأسعار إيقاف المشاكل التضخمية داخل الأسواق، حيث يشير بحثنا الى ان هنالك علاقة عكسية ما بين فاعلية السياسة الانفاقية ومعدل البطالة في العراق خلال مدة البحث، كما يجب ان تسعى الحكومة الى زيادة الانفاق التوسعي من اجل خفض معدلات التضخم العام عبر منهجية وسياسات مالية مدروسة، كما شمل البحث ثالث مباحث تمثل المبحث الأول الاطار النظري والمفاهيمي لفاعلية السياسة الانفاقية والمبحث الثاني الاطار النظري والمفاهيمي لمعدل التضخم والمبحث الثالث فقد شمل قياس وتحليل العلاقة ما بين فاعلية السياسة الانفاقية للحد من معدل التضخم في العراق للمدة (2004-2021).
Book Review: Merry Morash, In a Box Gender-Responsive Reform, Mass Community Supervision, and Neoliberal Policies.
Authors: Camacho David
Published: February 2025

Dr. Merry Morash, a Professor at the School of Criminal Justice
concluded a 6-year interdisciplinary mixed-methods study on the impact
of probation and parole services on women. The study combined
communication and psychology theories with criminal justice theories on
supervision and reentry from prison. The second phase focused on
women's identity change concerning recidivism and other life outcomes.
Dr. Morash is involved as a research partner with the Detroit Rescue
Mission Ministries' re-entry program for women and men transitioning
from prison to Detroit. Her research primarily centers on gender, crime,
and justice, wii
th publications on various topics such as women and girls
in the juvenile justice system, experiences of battered immigrant women
in the U.S., and women in law enforcement.
Visual Impairment in Stroke Patients: a Two-Part Review. Part II — Rehabilitation Methods
Authors: Marfina Tatyana V. , Konchugova Tatiana V. , Apkhanova Tatiana V. , Kulchitskaya Detelina B. , Mukhina Anastasiya   A.
Published: February 2025

INTRODUCTION. The search and development of optimal rehabilitation programs for patients who have suffered acute cerebrovascular accident (OMNA) is an urgent problem of modern medicine. The development of scientific and technical capabilities leads to the active introduction of the latest technologies at different stages of medical rehabilitation of cerebral stroke. This article is the second part of a two-part review devoted to the problem of visual impairment in patients with acute cerebrovascular accident, which provides an overview of the methods of rehabilitation of patients in this category.
MAIN CONTENT OF THE REWIEW. This overview of rehabilitation methods for patients with impaired visual functions who have undergone OMNA is based on publications in international and domestic databases OpenAlex, Scilit, Lens, PubMed, Cyberleninka and eLibrary available for analysis by 15.08.2024, with a search depth of mainly 15 years. As a result of the search, 66 articles on a given topic were reviewed. In addition, 6 sources dated from an earlier period (1989–2005) were used, as they contain the necessary information within the framework of this review. The rehabilitation methods considered in the review correspond to the accepted basic strategies for restoring impaired visual functions, including those caused by cerebral stroke. Two main strategies include the use of optical devices to adapt to the environment and training of intact structures of the visual analyzer aimed at compensating for lost functions. The third strategy is aimed at increasing the processing of visual information in areas of residual vision.
CONCLUSION. The variety of types of visual disorders, the degree of influence on the quality of life of stroke patients, necessitates the search and development of optimal rehabilitation programs. This will significantly expand the choice of recovery options after a cerebral stroke in this category of patients.
Modern View on the Etiology and Methods of Treatment of Bruxism: а Review
Authors: Terentyeva Elena V. , Yurova Olga , Dubinskaya Anastasia D.
Published: February 2025

INTRODUCTION. Currently, the prevalence of bruxism ranges from 9 % to 32 % of the total population, of which 6 % to 20 % are adults, while the question of the etiology of bruxism remains open, due to the presence of various theories of the development of this disease.
MATERIALS AND METHODS. The search was conducted for the period from 2002 to 2024 in the Medline database using the keyword "bruxism" and in the Elibrary database of the scientific electronic library using the keyword "bruxism". Articles that included a systematic review and meta-analysis (17 articles) and randomized clinical trials (26 articles) were analyzed.
MAIN CONTENT OF THE REWIEW. The possible causes of bruxism are considered to be the presence of stress factors, occlusal disharmony, dysfunction of the TMJ, parafunctional activity of the masticatory muscles, genetic factors, the presence of a number of concomitant diseases, taking medications, smoking, which requires an interdisciplinary approach both in the study of the etiology and in the treatment of such a multifarious disease as bruxism. The methods of treatment used in patients with bruxism can be divided into the following groups: intraoral: occlusal correction, occlusal caps, devices for advancing the lower jaw, etc.); intramuscular injections of botulinum toxin A; drug therapy; physiotherapy; biofeedback technologies (BFB); behavioral: relaxation techniques, cognitive therapy, psychological counseling; other: alternative or supportive treatments. The main effects of the treatment include: a decrease in muscle activity confirmed by various types of electromyography, a decrease in muscle symptoms such as the level of pain, soreness, discomfort, fatigue, both according to subjective questionnaires and according to clinical examination, as well as a decrease or cessation of tooth attrition or grinding. When choosing one of the intervention options to suppress or reduce the activity of bruxism, it is necessary to take into account the corresponding indications, contraindications and side effects of each treatment option, as well as the individual characteristics of the patient. However, to date, indications for the appointment of various differentiated methods of treating bruxism remain contradictory and, in some cases, insufficiently substantiated, there are no highly effective individualized methods of therapy and prevention of bruxism, while irrational treatment of this pathology can lead to serious health consequences.
CONCLUSION. Timely diagnosis and treatment of bruxism is an urgent problem of modern medicine, which is associated with the multifactorial nature of this disease, which determines the use of a differentiated approach to the treatment of bruxism, in order to normalize the functions of the dental system and the psychoemotional state of patients.
Effect of Ultrasound Combined with Dry Needling on Myofascial Pain in the Upper Trapezius : a Controlled Randomised Study
Authors: Nugraha Rahmat , Rahmatika Rahmatika , Sudaryanto Sudaryanto , Hasbiah Hasbiah , Erawan Tiar
Published: February 2025

INTRODUCTION. Myofacscial Pain Syndrome (MPS) Upper trapezius is a condition of tightness in the upper trapezius characterized by the appearance of myofascial trigger points in the upper trapezius muscle fibers. This causes pain and decreased elastitrapezius muscle fibers, resulting in cervical motion limitations.
AIM. To determine the effect of the addition of ultrasound to Dry needling intervention on reducing pain and increasing cervical range in the condition of upper trapezius MPS.
MATERIALS AND METHODS. This type of research is a quasi-experiment with a randomized pre-test-post-test control group design that uses 2 sample groups, where the treatment group is given Ultrasound Therapy and Dry needling intervention, and the control group is given Dry needling intervention only. The sample obtained was 30 people according to the inclusion criteria, then randomized into 2 groups, namely 15 people in the treatment group and 15 people in the control group. Data collection was obtained through measurement of tenderness using Visual Analog Scale (VAS) and measurement of Range of Motion (ROM) using a goniometer.
RESULTS AND DISCUSSION. Based on the independent sample t-test for the VAS scale, the value of p = 0.619 (mean difference of 3.767 control 3.553 treatment), and based on the Mann-Whitney test, the value of p = 0.074 for flexion ROM (mean difference of 17.00 control 12.33 treatment), p = 0.311 for lateral flexion ROM (mean difference of 9.33 treatment 8.00 control), and p = 0.494 for rotation ROM (mean difference of 13.33 treatment 11.67 control), which means that there is no significant difference in effect between the treatment and control groups.
CONCLUSION. The addition of ultrasound to the dry needling intervention resulted in an increase of 9.33 in lateral flexion and 13.33 in rotation which means this number is greater when compared to dry needling alone with an increase of 8.00 in lateral flexion and 11.67 in rotation. However, the addition of ultrasound did not result in a decrease in tenderness and a greater improvement in cervical flexion where the value of 3.767 in dry needling alone compared to the value of 3.553 in the addition of ultrasound and 17.00 12.33.
The Effect of Natural Mineral Water on Regulators of Gastroduodenal Motility in Young Adults: a Comparative Controlled Study
Authors: Shklyaev Aleksey Е. , Kazarin Daniil D. , Maksimov Kirill V.
Published: February 2025

INTRODUCTION. Drinking balneotherapy has long been successfully used for pathologies of the digestive system. However, the sanogenetic mechanisms of normalization of gastrointestinal motility when using drinking mineral waters have not been sufficiently studied.
AIM. To assess the dynamics of the level of hormones that regulate gastric motility with a single dose of moderately mineralized sulfate-sodium-calcium mineral water in a young adults to reveal their sanogenetic role in functional dyspepsia.
MATERIALS AND METHODS. 3 groups were formed: the first — 57 people with postprandial distress syndrome (PDS), the second — 57 with epigastric pain syndrome (EPS), the third — 56 healthy people. All subjects were assessed for gastroenterological symptoms using a specific validated Gastrointestinal Symptom Rating Scale (GSRS) questionnaire, and the levels of motilin and cholecystokinin in the blood were determined before and after taking 200 ml of mineral water.
RESULTS. The level of motilinemia in patients with PDS initially (9811.67 ± 48.34 pg/ml) did not have significant differences from the level of healthy people (9665.64 ± 106.94 pg/ml) (p = 0.379), with EPS it was lower (8780.67 ± 102.94 pg/ml) (p = 0.000). In healthy people, the concentration of motilin in the blood after taking mineral water did not undergo statistically significant changes (p = 0.59), in patients with PDS it led to a decrease in its level by 13.8 % (p = 0.000), in patients with EPS it increased by 9.3 % (p = 0.000). The value of cholecystokininemia in EPS (180.6 ± 5.83 pg/ml) turned out to be statistically significantly higher (p = 0.008), and in PDS (116.67 ± 3.32 pg/ml) lower (p = 0.000) than in healthy group (146.64 ± 6.24 pg/ml). After drinking mineral water, healthy people experienced an increase in cholecystokininemia by 21.5 % (p = 0.003), in the group of patients with PDS — by 43.6 % (p = 0.000), with EPS — without significant dynamics (p = 0.491).
CONCLUSION. Features of the dynamics of the level of motilin and cholecystokinin in the blood of healthy people and with functional dyspepsia in response to a single dose of mineral water were revealed, which play an important role in the sanogenetic effect of drinking balneotherapy for gastric motility disorders.
Resumption of Employment after Cervical Cancer Surgery: a 3-Year Follow-Up Study of Long-term Outcomes
Authors: Blinov Dmitry V. , Solopova Antonina G. , Gameeva Elena V. , Badalov Nazim G. , Eremushkin Mikhail A. , Stepanova Alexandra M. , Galkin Vsevolod N. , Ivanov Alexander E. , Akavova Saida A
Published: February 2025

INTRODUCTION. Despite advancements in cervical cancer (CC) diagnosis and treatment, surgical intervention remains the cornerstone of radical treatment. However, surgical procedures can result in complications such as lymphedema, sexual dysfunction, and other physical and psychosocial disorders, significantly affecting patients' quality of life (QoL) and ability to return to work. This emphasizes the need for effective strategies to support patients in resuming their occupational activities post-treatment.
AIM. To investigate the relationship between different rehabilitation programmes following cervical cancer surgery and return to work
MATERIALS AND METHODS. The study included patients aged 18 and older with stage 1A–1B cervical cancer. Patients were randomized into two groups: those receiving an active comprehensive rehabilitation program (СС-1, 51 patients) and those receiving passive rehabilitation (СС-2, 52 patients). The active rehabilitation program included a personalized, year-long regimen encompassing physical therapy, psychotherapeutic support, and lifestyle modifications, among other interventions. In contrast, the passive rehabilitation group received standard post-operative care information and general recommendations based on local clinical guidelines. The primary outcome was the proportion of patients who returned to work at various time points up to 36 months post-surgery.
RESULTS. Patients in the СС-1 group demonstrated significantly higher rates of return to work compared to the CC-2 group from the third month post-surgery onwards. At 36 months, all patients in the CC-1 group had returned to work, whereas only 66.7 % of patients in the CC-2 group had resumed their professional activities. In the CC-1 group the chance of returning to work within 3 years after surgery was 2.14 times higher compared to those in the CC-2 group (OR = 0.467, 95 % CI 0.309–0.706, p 0.001).
CONCLUSION. The study highlights the significant impact of personalized comprehensive active rehabilitation programs on improving the likelihood of return to work following surgical treatment for early-stage cervical cancer. These findings suggest that such rehabilitation approaches may be crucial in enhancing the long-term recovery and social reintegration of cervical cancer patients, ultimately contributing to better overall outcomes. Further research is needed to identify the most effective components of these rehabilitation programs and optimize their implementation.
Gender-related Differences in Rat Sciatic Nerve Regeneration after Autoplasty and Intraoperative Electroneurostimulation
Authors: Shchudlo Nathalia A. , Varsegova Tatyana N. , Kubrak Nadezhda V. , Stupina Tatyana A.
Published: February 2025

INTRODUCTION. According to the literature, intraoperative electrical neurostimulation (IES) after autoneuroplasty (AN) accelerates the regenerative growth of axons. It is unknown whether sexual dimorphism occurs in peripheral nerve regeneration after AN and with single-dose IES.
AIM. To identify possible gender-related differences in the regeneration of the sciatic nerve (SN) after AN resection of the defect of its tibial portion and a single IES in mature rats.
MATERIALS AND METHODS. 72 male (n = 39) and female (n = 33) rats underwent resection and AN of the tibial portion of the SN. Series 1 — non-stimulated control, series 2 — IES session 40 minutes. The tibial functional index (TFI) was calculated from the paw prints; Histomorphometric parameters of myelinated nerve fibers (MF) of the tibial nerve (TN) were determined.
RESULTS AND DISCUSSION. In series 1, 2 months after surgery, males were found to have higher values of the numerical density of MVs of the WBN and axon diameters (DA) than in females. After 4 months, YES and MV diameters are larger in females. After 6 months, females have greater myelin sheath (MS) thickness. TFI in series 1 decreases towards the end of the experiment, especially in males. In series 2, 2 and 4 months after surgery, in females the DA, MS, and MF diameters were greater than the values in series 1; after 6 months, only MS and MF diameters were greater. In series 2 males, 2 and 4 months after surgery, the MS and MF diameter are greater than in series 1, and after 6 months, all dimensional parameters in series 2 males are higher than in series 1 males. TFI in series 2 is greater than the values in series 1 and increases towards the end of the experiment, especially in males.
CONCLUSION. 2 months after AN, the growth and differentiation of nerve fibers in males is faster than in females, then the differences are inverted. Despite the increase in histomorphometric indicators of regeneration, in unstimulated animals, by the end of the experiment, TFI decreases, especially in males. In stimulated rats, compared to unstimulated ones, the morpho-functional indicators of regeneration at all periods of the experiment are better, to a greater extent in males.
Monitoring of Electrodermal Activity in the Diagnosis of Stress in Stroke Patients (3 Clinical Case Reports)
Authors: Kuzyukova Anna A. , Zagaynova Anastasia Yu. , Odarushenko Olga I. , Pekhova Yana G. , Nuvakhova Margarita B. , Marchenkova Larisa A. , Borisevich Olga O.
Published: February 2025

BACKGROUND. Common consequences of stroke are disabling neurological deficits, pain, cognitive and affective disorders that cause distress in patients, but generally accepted diagnostic methods are not always successful in detecting it. Currently, there is an increasing accumulation of data that the assessment of the level of sympathetic activation according to the parameters of electrodermalic activity (EDA) is effective for the diagnosis of stressful conditions.
AIM. To evaluate the possibility of objectification of stress by EDA parameters in stroke patients using examples of clinical observations.
CASES DESCRIPTION. In addition to clinical and metric assessment, EDA was registered in 3m stroke patients (I69.3) at the beginning and at the end of rehabilitation. In the 1st observation, the stress level of EDA indicators initially coincided with high levels of anxiety and depression, the reduction of which at the end of rehabilitation to optimal values led to normalization of EDA. In the 2nd case, at the beginning and at the end of rehabilitation, despite minimal neurological deficit, absence of pain and affective disorders and any complaints, stress indicators of EDA were recorded, due to previously undiagnosed alexithymia and persistent psychosomatic disorder. In the 3rd observation, a patient with a pronounced neurological deficit, who made increased demands on herself, initially normal EDA indicators, at the end of rehabilitation, in the absence of any complaints, changed to stressful ones due to overtraining.
CONCLUSION. The presented clinical observations can be useful for neurologists, psychologists, psychiatrists and psychotherapists, they demonstrate that taking into account ED indicators in a comprehensive assessment of the condition of stroke patients can increase the detection of stress and optimize rehabilitation measures.
Rehabilitation of a Patient with Knee Arthrofibrosis after Tibial Spine Fracture: a Case Report in Paediatrics
Authors: Rupasova Kseniya I. , Gukkina Olga O. , Zakharov Aleksei Yu. , Brusnichnikova Oksana A. , Lychanaya Natalia V. , Zakharova Olga V. , Karpov Sergei G. , Egorova Mariya V.
Published: February 2025

INTRODUCTION. Tibial spine fracture (TSF) is a rare injury, the incidence is higher among children. The common complication of treatment is arthrofibrosis. Early rehabilitation is important for its prevention. Guidelines haven’t been worked out.
CASE REPORT. Patient A., 11 years old, was operated for TSF. When she had hospitalized in medical rehabilitation center after 4 months, knee arthrofibrosis was diagnosed. Examination: range of knee motion is 180–155°. Edema of periarticular tissues. The gait pattern is impaired. She couldn’t maintained balance in Trendelenburg test on affected leg. Psychological diagnostics: fear of knee flexion, decreased motivation. Rehabilitation aims: A. will begin to bend knee while walking after 10–14 procedures d450.3.2–d450.2.1, b7100.2–b7100.1. A. is not afraid to bend knee during exercises by the end of the rehabilitation d240.2.0–d240.1.0. Rehabilitation program: physical exercises, mechanotherapy (treadmill, ladder with ramp, continuous passive motion), electrical myostimulation, aquajet therapy, vibrotherapy, kinesiotaping, hardware massage, sessions with psychologist, magnetic laser.
RESULTS AND DISCUSSION. Range of knee motion is 180–135°. Edema of tibia and hip has decreased. A. minimally bends knee when walking, hip flexion has appeared. A. can maintain balance in Trendelenburg test. The fear of bending knee has decreased according to self-assessment, but it is difficult for A. to cope with the situation of physical discomfort on her own. The aims have been partially achieved. Rehabilitation potential is low because of long period after surgery and personal characteristics. Life quality didn’t decrease, it made difficult setting rehabilitation aims. The team decided to focus on psychological work and improving motion.
CONCLUSION. Teamwork and guidelines are important for rehabilitation due to variety and complexity the pathology.
A Comparative Review of Traditional and Prospective Methods for Vitiligo Treatment
Authors: Olisova Olga Yu. , Kayumova Lyailya N. , Eremin Petr S. , Gilmutdinova Ilmira R. , Pinegin Vladimir B. , Kryuchkova Kira Yu. , Lomonosov Konstantin M.
Published: February 2025

INTRODUCTION. Vitiligo is an acquired skin disease characterized by loss of pigmentation with the destruction of epidermal melanocytes. The etiology and pathogenesis of this disease are still poorly understood. The course of vitiligo affects the patient's quality of life, his psychological state and self-esteem. In this regard, there is a need to develop new and promising methods aimed at stimulating and modulating the reparative processes of damaged tissues.
AIM. To review the scientific literature on traditional therapy and new approaches to the treatment of vitiligo.
MATERIALS AND METHODS. The literature review was conducted using the RINTS, PubMed and ScienceDirect databases. Query dates — March–July 2024, query depth — 1964–2024.
MAIN CONTENT OF THE REVIEW. Conservative treatment methods are aimed at inhibiting the pathological process, preventing the appearance of new spots and reducing the cosmetic defect. Thus, patients are prescribed topical and systemic glucocorticosteroids, calcineurin inhibitors, immunosuppressants, phototherapy both in monotherapy and in combination. In recent years, technologies based on transplantation of autologous suspension of regenerative skin cells have been considered the most promising.
CONCLUSION. Innovative methods of regenerative medicine are a good alternative to traditional treatments for patients with stable vitiligo, especially for those who do not respond to standard drug therapy.
The Effect Of Tax Planning, Deffered Tax Expense, Deffered Tax Asset and Tax Avoidance On Earnings Management
Authors: Hanifah Nur Fadilah , Abukosim Abukosim , Kesuma Nilam
Published: February 2025

This study aims to examine the impact of tax planning, deferred tax expense, deferred tax asset and tax avoidance on earnings management. The population for this research consists of LQ45 companies listed on the Indonesia Stock Exchange between 2019 and 2023. A total of 130 samples were selected using the purposive sampling method. The data analysis was conducted using multiple linear regression with SPSS 27. The findings indicate that tax planning, deferred tax expense and tax avoidance do not affect on earnings management, while deferred tax assets have a positive effect on earnings management.
Construcción de secadores solares tipo túnel con nuevos materiales
Authors: Oliveros-Tascón Carlos Eugenio , Ramírez César Augusto , Tibaduiza-Vianchá Carlos Alfonso , Sanz-Uribe Juan Rodrigo
Published: February 2025

Los secadores solares parabólico y túnel, diseñados en Cenicafé, se utilizan ampliamente en fincas cafeteras en Colombia para atender las necesidades de caficultores con producción anual de hasta 200 @ de café pergamino seco (c.p.s.), como única tecnología para el secado, y en combinación con secado mecánico en fincas de mayor producción, cuando se tienen días de menor flujo de cosecha. También se utilizan para pre-secar el café en fincas que disponen de secador mecánico, con ahorro importante de energía (eléctrica y térmica), reducción de emisiones de gases de efecto invernadero y de partículas.
�C�mo usar el hongo Beauveria bassiana para proteger su cosecha de caf�?
Authors: G�ngora Carmenza Esther
Published: February 2025

Una de las ventajas del uso de este hongo para el control de la plaga es su amplia distribuci�n geogr�fica, es decir, se ha encontrado en todos los lugares donde se ha buscado, lo que permite que est� muy bien adaptado y pueda vivir en los mismos lugares en los que vive la broca.
Per�odo cr�tico del ataque de la broca del caf�
Authors: Arcila-Moreno An�bal
Published: February 2025

En Colombia el establecimiento de la broca se ha favorecido debido a las condiciones ambientales que permiten producci�n continua de granos durante todo el a�o. La mejor manera de combatir a este insecto es implementando un programa de manejo integrado, para esto es necesario conocer el per�odo cr�tico del ataque de la broca del caf�, para lo cual es necesario conocer las �pocas de floraci�n, el crecimiento del fruto y su relaci�n con la plaga.
Vuelos de la broca del caf� durante la cosecha principal
Authors: Benavides Pablo
Published: February 2025

En general, en per�odos de sequ�a, existe una mayor reproducci�n de la broca dentro de los frutos secos que est�n en los �rboles y en los frutos infestados del suelo. Adem�s, el desarrollo de la broca es m�s r�pido Por el contrario, cuando comienzan las lluvias, la broca sale a volar de los frutos infestados, no permanece mucho tiempo en �stos, produce menos descendencia, y al perforar los frutos, puede morir por la acci�n de agentes naturales de control, como los hongos entomopat�genos.
A 2001-es beregi árvíz tizedik évfordulóján túl
Authors: Muhoray Árpád
Published: February 2025

The bursting of the Tarpa dam in the Tisza basin, was one of the largest natural disasters of the last century in Hungary. Highlighting the most important modifications of the new Disaster Management Law that came into force on the 1st January 2012, and reflecting on the 10th anniversary of the flood, the author recalls the chronicle of the events, the organization of defence activities, and experiences on rebuilding and resettling.
A szellemi tulajdont sértő bűncselekmények nyomozásának néhány tapasztalata és az üldözés lehetőségei
Authors: Mészáros Ádám , Szabó Imre
Published: February 2025

Aiming to provide recommendations for the legislator, and to demonstrate changing social attitudes, the author provide an overview of an empirical research on investigating crimes against intellectual property.
Huszonhat interjú
Authors: Tátrai Miklós
Published: February 2025

The author provides on overview and an analytical assessment of the threevolume book he recently published, and which contains lengthy interviews with twenty-six generals on their career, as well as reflections and memories on politics and the law enforcement profession.