bluuebunny/crossref_metadata_2025 huggingface dataset:
Relações interpessoais na escola e o desenvolvimento local
Authors: Fakhouri Baia Samira , De Souza Machado Lucília Regina
Published: June 2021

As relações interpessoais na escola são um elemento importante na constituição do desenvolvimento local. Elas são reveladoras da dinâmica territorial com respeito às situações de desagregação decorrentes da busca de afirmação de interesses de grupos, mas também denotam os bons feitos das pretensões de fazer conviver com harmonia as diversidades culturais e a construção das identidades. Este artigo traz resultados de revisão teórica interessada em conhecer conceitos e abordagens sobre relações interpessoais na escola e propostas educacionais de enfrentamento desse desafio. Três das principais conclusões encontradas: os problemas de relacionamento que afetam a convivência na escola e o desenvolvimento local têm origem primordial na estrutura social; a violência e a intolerância, em quaisquer graus, afetam os direitos humanos e as possibilidades da inclusão social pela educação; há experiências concretas que mostram ser possível melhorar as relações interpessoais na escola.
Todo mundo é igual? Construções de gênero sob o olhar da juventude
Authors: Gonçalves Nascimento Caroline , Holz Waskow Millena , Neves Strey Marlene , Brandelli Costa Ângelo
Published: June 2021

A escola pode revelar, entre outras coisas, situações e procedimentos pedagógicos e curriculares relacionados à produção de diferenças e distinções sociais que interfiram na formação e na produção social do desempenho escolar. A Educação de Jovens e Adultos é um sistema de ensino da rede pública no Brasil que oportuniza àqueles que não tiveram acesso à escola quando ainda eram crianças, seja qual for o motivo, que se alfabetizem, obtendo assim o que é um direito à cidadania. O presente artigo é resultado de uma investigação que objetivou analisar construções de gênero na juventude a partir das percepções de alunas(os) da modalidade de ensino Educação de Jovens e Adultos. Foram expostas publicações da rede social Facebook, com a temática “gênero”, a estudantes com idades entre 15 e 29 anos de uma escola municipal da região metropolitana do Rio Grande do Sul. Para tanto, foram organizados cinco grupos focais, nos quais se buscou analisar as construções sociais de gênero, na perspectiva das(dos) jovens, a partir do método da análise temática. Os principais resultados revelam como as construções de gênero apresentam-se de forma plural para as(os) jovens na sociedade atual, até mesmo em função de terem vivências diferentes de vida.
Marketing territorial aplicado a distritos industriais: estratégia de inovação para empreendedorismo e desenvolvimento local
Authors: Da Fonseca Capssa Lima Sausen Juliana , Oneide Sausen Jorge , Knebel Baggio Daniel , Luís Allebrandt Sérgio
Published: June 2021

O distrito industrial é importante para o desenvolvimento econômico e social, local e regional, enquanto o marketing territorial é relevante para a implementação de ações de empreendedorismo e desenvolvimento. Considerando o potencial de indústrias, as demandas do Corede Noroeste Colonial, no Rio Grande do Sul, e os distritos industriais e o marketing territorial como base teórico-conceitual, o objetivo deste trabalho foi identificar, compreender e analisar as limitações e oportunidades das áreas industriais desta região, diante do seu contexto, articulações e dinâmicas de empreendedorismo e desenvolvimento, à luz das estratégias de marketing territorial. Foram realizadas entrevistas com agentes públicos e gestores empresariais das áreas industriais desta localidade. Verificou-se a expansão de mercado das indústrias, diversidade de produtos e serviços, bem como conscientização dos envolvidos quanto à relevância da interação e cooperação entre atores e dos processos de inovação para o desenvolvimento destas áreas. Constatou-se, porém, demandas quanto à visão empreendedora dos atores, regularização das áreas, infraestrutura, logística e recursos, fatores estes comprometedores do empreendedorismo e desenvolvimento local. Concluiu-se que tais aspectos demandam estratégias de marketing territorial para fortalecer a cooperação entre agentes públicos e privados, contribuindo para captar recursos e desenvolver as dinâmicas territoriais por meio de ações eficazes de governança, empreendedorismo e inovação.
Indicadores organizacionais e planejamento sucessório em empreendimentos rurais de grande porte: um estudo no estado de Mato Grosso
Authors: Sznitowski Adelice Minetto , Sousa Priscylla Cordeiro de , Thiago Fernando
Published: June 2021

O objetivo desta pesquisa consistiu em verificar a influência dos indicadores de gestão no planejamento de sucessão em empreendimentos rurais de grande porte. Os indicadores utilizados envolvem: liderança, decisão, controle, planejamento, comunicação e motivação das pessoas nas organizações participantes, de forma a identificar o estilo de gestão utilizado pelos seus gestores. Entende-se por sucessão familiar a transferência da gestão de um membro da família para outro membro de geração posterior. Essa questão nos empreendimentos rurais é recorrente; no entanto, as práticas de gestão supracitadas podem minimizar tal situação, o que contribui para a continuidade da organização. O método utilizado foi de base quantitativa e descritiva, utilizando a técnica de levantamento (survey). Os dados foram coletados por meio do Instrumento de Avaliação do Estilo de Gestão, que possibilita recolher informações sobre os indicadores mencionados. Os resultados dos indicadores de gestão relacionados com o planejamento sucessório evidenciam diferenças entre os dois grupos analisados: gestores membros da família e contratados não membros da família. Observou-se que os empreendimentos que planejam sucessão têm melhor percepção de seu desempenho, considerando os indicadores referentes ao estilo de gestão. Desse modo, os gestores membros da família apresentam melhor desempenho quando comparados com os gestores que não são membros da família.
Smart Cities: extrafiscalidade como indutora do desenvolvimento de cidades inteligentes
Authors: De Carli Franco Guerino , Ribas Lídia Maria
Published: June 2021

O presente artigo aborda as cidades inteligentes, levando em consideração a criação e o desenvolvimento dos direitos humanos e o desenvolvimento sustentável como um direito humano. As cidades inteligentes representam uma forma de promoção de vida digna aos seus moradores, pois elas adquirem essa denominação em razão do atendimento de protocolos que visam à obtenção de mobilidade, de utilização de tecnologia e energia limpa, de realização de ações que promovem o desenvolvimento social e econômico de forma justa, de urbanismo, de governança, entre outros. O objetivo geral da pesquisa é verificar a existência de relação entre a concepção de cidades inteligentes e a promoção dos direitos humanos, bem como a utilização da extrafiscalidade como indutora do desenvolvimento de cidades inteligentes. A fim de responder a esse questionamento, um dos possíveis instrumentos a serem utilizados é a tecnologia, para transformar os centros urbanos em ambientes mais humanos. Para isso, a pesquisa aborda a importância da implementação do uso de Tecnologias da Informação e Comunicação (TICs), presente nas cidades denominadas “inteligentes”, como forma de se oportunizar mais igualdade aos moradores das cidades, maior dignidade e qualidade de vida, garantindo, assim, uma maior efetividade aos direitos humanos das pessoas que vivem em centros urbanos. Para a consecução desses objetivos, foi utilizado o método hipotético-dedutivo de abordagem, com a realização de pesquisa bibliográfica e documental. Chegou-se à conclusão de que a cidade que consegue implementar aspectos do conceito de Cidades Inteligentes e Humanas oportuniza mais igualdade aos moradores, maior dignidade e qualidade de vida, garantindo, assim, uma maior efetividade aos direitos humanos das pessoas que vivem em centros urbanos, com a criação de mecanismos de estímulos à adoção de posturas, por particulares, com a utilização da tributação – na modalidade extrafiscal.
Rural development in the Sertão do São Francisco, Bahia: an interpretation based on the trajectories of peasant families of the territory
Authors: Monteiro Denis , Guedes Cezar Augusto Miranda
Published: June 2021

This article addresses the trajectories of peasant families of the rural areas in the municipalities of Juazeiro, Casa Nova, Campo Alegre de Lourdes, and Remanso development, in the Sertão do São Francisco territory, semiarid Bahia, Brazil. It aims to interpret the processes of rural development in the territory based on the results of innovations incorporated by families from the interaction in learning networks mobilized by non-governmental organizations and access to a set of public policies. The Lume method was used to guide the economic and ecological analysis of agroecosystems. In its recent history, this territory was the beneficiary of several policies of tackling misery and hunger through Zero Hunger (Fome Zero) and Brazil without Extreme Poverty (Brasil sem Miséria) governmental programs, aimed at peasant farming. The incidence of extensive territorial development policies conducted by innovative institutionalities is another feature that called the attention of the research. A significant ensemble of innovations has been incorporated to the agroecosystems, to which contributed the public policies of the democratic period and, most importantly, the social capital of the territory resulted from the mobilization of the peasantry as well as from their partner organizations. The trajectories of analyzed families show how food production for self-consumption of the families, the reciprocity of give-and-take actions and the trading in a big diversity of local markets, while empowering the families’ struggle for autonomy, also contributes to summon social active strength for the construction of rural development alternatives aimed at both making peasant farming stronger and ensuring food sovereignty of the territory.
On the Basic Categories of Facilitative Pedagogy
Authors: Avdeeva Irina , Hrabrova Valeria , Аdonina Larisa , Shutova Olga , Rusnakova Elizaveta
Published: June 2021

A key characteristic of a learner-centered educational process is its realization as a subject-to-subject interaction between participants. At present, a view that the goal of the pedagogical process is to create conditions for the development of a creative and moral personality, independent in cognitive and practical activities, free to choose a professional, social, family career can be considered customary. A rounded actualized personality is, first of all, the subject of human relations and conscious self-work. That is, this is a person who has a conscious and stable system of relations to themselves and the world, who is able to realize the motives of their activities, set a goal, and independently regulate their own actions to achieve it. A teacher positions oneself as a facilitator in this interaction, and a firm promotion of the student’s ability to be the subject of one’s own relationships, behavior, becomes the main principle of professional work of both each teacher taken separately and the teaching staff as a whole.
El diagnóstico psicopedagógico para la inclusión socioeducativa de los escolares con necesidades educativas especiales
Authors: Martínez Pablo A. , Pérez Lismay , Alvarez Marieta
Published: June 2021

El presente artículo expone los resultados obtenidos como parte del trabajo desarrollado en una de las tareas del proyecto de investigación “La Pedagogía Especial como sustento para la inclusión socioeducativa de los escolares con necesidades educativas especiales (NEE)”, dirigida a la elaboración de acciones didáctico metodológicas para la realización del diagnóstico psicopedagógico como sustento de la inclusión socioeducativa de los escolares con NEE.
Problems and Prospects for the Development of Professional Pedagogical Activity in the Context of IT Penetration into Education
Authors: Mikhailenko Olga Ivanovna , Vakulenkova Marina Vladimirovna , Sharova Elena Ivanovna , Sokolova Angela Vladimirovna , Temnikova Elena Yuryevna
Published: June 2021

All this speaks of the need to improve the theoretical and methodological provisions and practical recommendations of professional and pedagogical training of university teachers in the conditions of informatization of education.
Comparison of Ardabil people's utilization of national media and satellite networks in receiving news
Authors: Baratchian Taher , Hashemi Shahnaz , Jafari Ali , Soltani Far Mohammad
Published: June 2021

Since the national media should be the most important medium in getting the news to a community, as an emerging media social networks have been able to take deep root in human life. These networks have positive features, but on the other hand, they have problems that need special attention.
Information technologies in teaching humanitarian disciplines
Authors: Morozova Irina M. , Lyusev Valery N. , Gladkova Marina N. , Smirnova Elena V. , Kulagina Julia A.
Published: June 2021

The study made it possible to reveal the influence of information technologies on the level of formation of students' competencies.
Moral and Spiritual Self-Improvement of Russian Youth in the Context of Religious and Cultural Awareness
Authors: Mukhametzyanova Flera Gabdulbarovna , Krasnoshchechenko Irina Petrovna , Fakhrutdinova Anastasia Victorovna , Ilicova Lilia Ernstevna
Published: June 2021

In the research the relation to a symbol of the icon of Kazan Mother of God is considered through the structure of identity of group of modern Cristian youth. Today the religiousness, religious belief is a psychological phenomenon focusing the person on a way of moral and spiritual self-improvement. The relation of citizens to Russian Cristian Church remains contradictory, especially at youth. In this regard the research of the relation to a unique historical and cultural and spiritual symbol of the Kazan icon of the Mother of God is perspective. It is one of the brightest and deepest Cristian symbols it content. History of the Kazan icon of the Mother of God is inseparably linked with the history of Russia. The purpose of this article is to present the results of the research aimed in the identification of the relation to a symbol of the Kazan icon of the Mother of God of modern Cristian youth in the context of interrelation of its confessional identity and religious and cultural awareness. Results of an empirical research allows to establish that, despite growth of religious interest in a symbol of an icon of Kazan Mother of God at young people the low level of knowledge, not formation of ideas of the historic facts connected with this icon is observed. The image of an icon and its historical context have the invaluable potential for spiritual and moral education of the Russian youth.
Communication skills and social interaction in university students from Lima
Authors: Guillén-Chávez Sergio Raúl , Carcausto Wilfredo , Quispe-Cutipa Walter Arturo , Mazzi-Huaycucho Víctor , Rengifo-Lozano Raúl Alberto
Published: June 2021

The present study aims to establish the correlation between communication skills and social interaction among students of the Faculty of Education of a public university in Lima. The research is framed under the positivist paradigm, with a quantitative approach, a basic type, of the non-experimental design, with a cross section, of the sub-type of correlational design.
ORGANIZATIONAL STRESS
Authors: Mihailović Dobrivoje
Published: June 2021

Contemporary organizational psychology very often lakes problem of organizational stress as one of its subjects. It is a phenomenon with which almost every profession must deals, but some of them are more exposed to its jeopardizing influences. For some professions stress is part of almost every work aspect. Nevertheless, it is usual to connect stress with the problem of conflicts. The importance of studying stress is especially actualized in situations of social and economics crisis that are characteristic for modem age and our environment. This paperwork is an attempt to give a theoretical explanation of work stress through identification and systematization of sources of stressias it is an attempt to describe far-reaching and complexity of its consequences on person and organization. Also, there is an idea to show methods that can be sued for managing stress, through organizational measures, or through techniques for individual coping with stress. We started from the hypothesis that it is possible to look for sources of organizational stress in organization itself, connected with the nature of work, organizational role that one has, in the degree of his responsibility, work relations, dynamics and psychological climate in organization, and if factors outside the organization (in family, life difficulties, personal conflicts). The consequences of stress can be seen on the level of physiological and psychological interruptions, and on the level of organizational problems. Consequently, on one side the importance of adequate professional selection and education, and adequate organizational culture is seen as important measure for stress prevention, and there us an emphasizing of personal techniques for protecting, mitigation and recovering of the stress, on the other side.
THE HOTEL ENVIRONMENT AND MANAGEMENT
Authors: Pavia Nadia
Published: June 2021

Keeping up with new market trends is a demand on the hotel management made by the conditions in which hotel operations are today conducted. The ability to adapt to changes is a prerequisite for the growth, development and survival of hotel enterprises. The two most important factors of the organizational environment are competition and hotel guests. The hotel management should center its activities on the hotel guests and the demands of the tourist market.
INTERNET DICTIONARIES OF TERMS IN FRENCH FOR TOURISM INDUSTRY
Authors: Škunca Jadranka
Published: June 2021

In the last twenty years the computer has become the main means of access to highly specialized knowledge and also a protected way of transmission of information in the field of science, technics, literature and arts. The process started by the computerization of librarian catalogues as well by linking of big publishers onto database as PASCAL. Publishers of specialized journals, of press, professional associations and publishing houses made their publications accessible on the computer network, they listed and created their own archives and also made possible the access to research centres, scientific and research workers, publishers and interested readers. In this research work we tried to look up the dictionaries of terms in the field of tourism industry, in French, in the electronic form. Nowadays, the dictionaries of terms can be found in Internet and they are accessible to a wide range of users because they are easily and quickly obtainable. We made a research of various dictionaries of terms in the field of tourism industry in French and the most interesting ones were described.
COMPUTER SYSTEM OF HOTEL MAINTENANCE
Authors: Galičić Vlado
Published: June 2021

The mere idea of maintenance today has been extended. It is not only the technical systems that are being maintained in order to keep them in operating conditions, also the environment (water, air, soil) is maintained, flora and fauna are maintained, man maintains his health etc. In the last few years developed tourist countries with developed hotel industry as their main tourist receptive tool, have as part of strategies for their development defined maintenance as one of the significant elements of complete development, but also of business quality improvement. The function of maintenance comprises the jobs and activities performed to ensure correctness, i.e. functional usability of instruments of labour. The characteristic of today's maintenance of a hotel as a catering establishment lies in the fact that it is performed on concrete equipment and it has a practical impact on successful running of the hotel. Since the equipment in a hotel comprises different groups of equipment: mechanical, electrical, building- particular approach is required when selecting the maintenance strategy for a particular group of equipment. However, computer support is essential to every strategy in order for the maintenance service to become effective. Related to that, the managing computer system for hotel maintenance must support preventive, planned and corrective maintenance.
MARKETING MANAGEMENT DER DIENSTLEISTUNGEN IM HOTEL
Authors: Berc Radišić Branka
Published: June 2021

Das Management des Hotelmarketing ist ein Prozess der Planung, Organisierung, Anwendung und der Kontrolle des Hotelproduktabsatzes. Dieser Prozess wird durch die Hotelmarketingsabteilung an der Spitze mit dem Hauptmarketingsmanagement bewegt und geführt. Der Hoteleigentümer sollte die Marketingsabteilung als den Schlüsselfaktor einer erfolgreichen Geschäftsführung erkennen und dementsprechend die Notwendigkeit ersehen diese anzuregen und zu stimulieren.
LEXICAL ASPECT OF HOTEL BROCHURES
Authors: Blažević Nevenka
Published: June 2021

Propaganda is the most important marketing instrument in the hotel industry. Every propaganda campaign pays special attention to the linguistic aspect of the propaganda materials. This paper analyzes the lexical aspect of hotel brochures. The most frequent lexical patterns are listed and sorted as they appear in hotel brochures. The terms used in hotel brochures have informative and emotional function. Emotional function is usually expressed by adjectives. Adjectives, as well as the other lexical terms, should be chosen carefully, because each wrong word may cause negative consequences.
The Impact of Surgical Site Infection on Patient Outcomes After Open Posterior Instrumented Thoracolumbar Surgery for Degenerative Disorders
Authors: Urquhart Jennifer C. , Gurr Kevin R. , Siddiqi Fawaz , Rasoulinejad Parham , Bailey Christopher S.
Published: June 2021

Background:

Few reports in the literature have described the long-term outcome of postoperative infection from the patient perspective. The aim of the present study was to determine if complicated surgical site infection (SSI) affects functional recovery and surgical outcomes up to 2 years after posterior instrumented thoracolumbar surgery for the treatment of degenerative disorders.

Methods:

This retrospective cohort study involved patients who had been enrolled in a previous randomized controlled trial that examined antibiotic use for open posterior multilevel thoracolumbar or lumbar instrumented fusion procedures. In the present study, patients who had SSI (n = 79) were compared with those who did not (n = 456). Patient-reported outcome measures (PROMs) included the Oswestry Disability Index (ODI), leg and back pain scores on a numeric rating scale, Short Form-12 (SF-12) summary scores, and satisfaction with treatment at 1.5, 3, 6, 12, and 24 months. Surgical outcomes included adverse events, readmissions, and additional surgery.

Results:

The median time to infection was 15 days. Of the 535 patients, 31 (5.8%) had complicated infections and 48 (9.0%) had superficial infections. Patients with an infection had a higher body mass index (BMI) (p = 0.001), had more commonly received preoperative vancomycin (p = 0.050), were more likely to have had a revision as the index procedure (p = 0.004), had worse preoperative mental functioning (mental component summary score, 40.7 ± 1.6 versus 44.1 ± 0.6), had more operatively treated levels (p = 0.024), and had a higher rate of additional surgery (p = 0.001). At 6 months after surgery, patients who developed an infection scored worse on the ODI by 5.3 points (95% confidence interval [CI], 0.4 to 10.1 points) and had worse physical functioning by −4.0 points (95% CI, −6.8 to −1.2 points). Comparison between the groups at 1 and 2 years showed no difference in functional outcomes, satisfaction with treatment, or the likelihood of achieving the minimum clinically important difference (MCID) for the ODI.

Conclusions:

SSI more than doubled the post-discharge emergency room visit and additional surgery rates. Patients with SSI initially (6 months) had poorer overall physical function representing the delay to recovery; however, the negative impact resolved by the first postoperative year.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Application of laser induced breakdown spectroscopy (LIBS) for environmental, chemical, and biological sensing
Authors: VerMeulen Holly , Clausen Jay , Mossell Ashley , Morgan Michael , Messan Komi , Beal Samuel
Published: June 2021

The Army is interested in sensors capable of characterizing/monitoring the environment (battlefield or military training ranges) at proximal distances. Recently, we evaluated laser induced breakdown spectroscopy (LIBS) systems (hand-held, proximal, and bench top) for the characterization of metals (antimony, copper, lead, tungsten, and zinc) in soils obtained from military training ranges. We then compared the results to findings obtained with standard field and laboratory instrumentation for metals analysis -X-ray Fluorescence (XRF) and Inductively Couple Plasma- Optical Emission Spectroscopy (ICP-OES).
Fishing in your backyard: otters that prey on urban resources
Authors: Duarte Jesus , Rodríguez Diego , Farfán Miguel Ángel , Fa Julia E.
Published: June 2021

We monitored the incidence of predation behavior in Eurasian otters (Lutra lutra) from urban ponds in southern Spain, following reports of the mustelids’ presence in various urban locations. In one of the case studies, 30 small common carp and 35 Koi fish were released in May 2017 and April 2018, respectively, into two different ponds. Otters extensively predated on these fish over a period of 75–80 days. Only two small carp (6.6%) survived in one of the ponds and 10 Koi fish (28.5%) in the other. The surviving Koi were relocated. We determined that fish survival functions and mortality rates between these two years were not significantly different. At the second urban location, otters extensively predated on Iberian frogs over a period of 5–6 days in May 2018, left the area, and repeated this pattern in May 2019. Finally, at the third urban location, otters consumed 20 goldfish in 16 days in August 2018. Our results indicate that available food resources in urban settings can become a viable option for certain bold individuals of wildlife species and that otters appear to explore urban habitats when it suits them. Appropriate management and damage control strategies are therefore needed to ensure the survival of this protected species in case food resources in the wild become limited and urban raids become habitual.
Numerical and experimental investigations on cutting force of broaching internal spline holes
Authors: Ying Shenshun , Fu Chentai , Zhang Shunqi , Lin Lvgao
Published: June 2021

Cutting force in broaching process is essential information for quality controlling, troubleshooting and tool life prediction, yet existing technical bottleneck in prediction and acquirement in internal spline holes broaching process. Based on the mechanics of orthogonal metal cutting, a numerical model of the cutting force in internal spline broaching is constructed by Johnson-Cook material constitutive and failure model taking friction on both rake face and flank face into consideration, and is used to numerically estimate the cutting forces. A measurement apparatus is developed and real-time cutting force is monitored, which contains the effects of structural vibration and can be divided into static cutting force and dynamic cutting force. Wavelet transform filtering method is therefore employed to separate the static component from dynamic component. Calculated value of the cutting force by numerical model is in good agreement with the static cutting force by experimental measuring. The model and measurement method are feasible in intelligent manufacturing where internal broaching process is used.
The Impact of Radiation Therapy Variables on Pediatric High-Grade Glioma Outcomes: A National Cancer Database Analysis
Authors: Williamson Christopher , Williamson Shayla , Jiang Renjian , Sudmeier Lisa , Esiashvili Natia , Eaton Bree R.
Published: June 2021

Purpose
Pediatric high-grade glioma (HGG) is a devastating disease with a poor prognosis. The purpose of this analysis is to evaluate the impact of Radiation Therapy (RT) variables on outcomes of pediatric HGG patients in the National Cancer Database (NCDB).
Methods
The NCDB was used to select patients age < 22 with histologically proven WHO Grade III and IV gliomas treated with ≥ 50Gy and < 76Gy RT between 2004 and 2013. RT variables including RT dose, timing between diagnosis and RT initiation (< 4 weeks, 4–6 weeks, or > 6 weeks), and RT modality were analyzed along with baseline demographic, tumor and treatment variables to assess the impact on overall survival in univariate and multivariable analyses.
Results
498 pediatric HGG patients were included. Histologies included glioblastoma (30%), astrocytoma (55%), oligogendroglioma (5%) and gliomas not otherwise specific (10%). The median RT dose was 59.4 Gy (SD 2.9 Gy) starting a median of 4.4 weeks from diagnosis (SD 2.5 weeks). Median follow-up was 19.6 months with 1- and 3-year OS of 78.4% and 40.4%, respectively. On Multivariable analysis, female gender, older age, and private insurance remained independently associated with lower rate of overall death. Radiation initiation ≤ 4 weeks from diagnosis, and glioblastoma histology were significantly associated with higher rate of overall death. There was no relationship between radiation dose or whether radiation was delivered with proton or photon therapy and overall survival.
Conclusions
Outcomes for pediatric HGG are poor. Early initiation of RT within 4 weeks from diagnosis was negative associated with overall survival and may be related to unknown prognostic factors.
A New Solution for D2D Assisted 5G AR Communications
Authors: Urosevic Ugljesa , Veljovic Zoran
Published: June 2021

Device-to-Device (D2D) communications are one of the main drivers of new wireless standards. D2D improves resource utilization, spectral efficiency, energy efficiency and cellular coverage of wireless networks. In some applications like online gaming, video streaming and multimedia downloading, performances can be deteriorated for users at cell edges. This is particulary emphasises in the case of augmented reality (AR) and virtual reality (VR) technologies. AR is a highly visual, interactive method of presenting relevant digital information in the context of the physical environment, e.g. connecting employees and improving business outcomes. In this paper, a new communication scheme with D2D assistance is proposed, which can significantly increase the spectral/energy efficiency in 5G AR use cases. The proposed scheme combines multiple input multiple output (MIMO) techniques, relaying and spatial modulation (SM). It allows the formation of virtual MIMO unicast, SM multicast, and SM unicast channels between AR devices. The simulation results show that spectral/energy efficiency can be significantly increased without significantly impairing bit error rate (BER) performance.
Development Of Highly Durable Superhydrophobic And UV-Resistant Wood By E-Beam Radiation Curing
Authors: Li Yulong , Xiong Zhi , Zhang Mingxing , He Yulong , Yang Yan , Liao Youwei , Hu Jiangtao , Wang Minglei , Wu Guozhong
Published: June 2021

Developing a practical strategy to fabricate an anti-abrasion and durable superhydrophobic wood surface with ultraviolet (UV) resistance has great practical significance for expanding the application of natural wood. In this study, a robust superhydrophobic layer with a hierarchical micro/nano-roughness structure was modified on the wood surface through in-situ mineralization and polymerization using a simple sol–gel method along with efficient electron beam (EB) curing technology. Hydrophobic agent (polydimethylsiloxane, PDMS), and crosslinking monomer (γ-methacryloxypropyl trimethoxysilane, MAPS) form new covalent bonds between TiO2 particle layer and wood substrate after EB radiation，which endows robust superhydrophobicity and remarkable UV resistance on the wood surface. The as-prepared wood exhibited a water contact angle (WCA) of approximately 165.7° and obvious repellency to many aqua-phase liquids (cola, strongly acidic, alkaline droplets etc.). Furthermore, the hierarchical micro/nano-protrusion structures remained unchanged and micro/nano particles aggregated tightly on the as-prepared wood surface under harsh external environments (sandpaper abrasion and, ultrasonic treatment), confirming the desirable anti-abrasion and mechanically durable performance of the superhydrophobic surface. After the 18-day UV accelerated weathering test, the TiO2 particle layer conspicuously retained the discoloration and maintained its exceptional repellency toward water. The biomimetic superhydrophobic wood with excellent mechanical durability and UV resistance reveals its potential application in the furniture and architecture fields.
Endemism in Recently Diverged Angiosperms Is Associated With Chromosome Set Duplication
Authors: Villa Sara , Montagna Matteo , Pierce Simon
Published: June 2021

Chromosome set duplication (polyploidy) drives instantaneous speciation and shifts in ecology for angiosperms, and is frequently observed in neo-endemic species. However, the extent to which chromosome set duplication is associated with endemism throughout the flowering plants has not been determined. We hypothesised that across the angiosperms polyploidy is more frequent and more pronounced (higher evident ploidy levels) for recent endemics. Data on chromosome counts, molecular dating and distribution for 4210 species belonging to the major clades of angiosperms were mined from literature-based databases. As all clades include diploid taxa, with polyploids representing a possible ‘upper limit’ to the number of chromosomes over evolutionary time, upper boundary regression was used to investigate the relationship between the number of chromosomes and time since taxon divergence, both across clades and separately for families, with endemic and non-endemic species compared. A significant negative exponential relationship between the number of chromosomes and taxon age was evident across angiosperm clades (R2adj=0.48 with endemics and non-endemics considered together, R2adj=0.46 for endemics; R2adj=0.44 for non-endemics; p ≤0.0001 in all cases), which was three times stronger for endemics (decay constant=0.12, cf. 0.04 for non-endemics). The majority of families exhibited this relationship, with a steeper regression slope for endemic Campanulaceae, Compositae, Leguminosae, Poaceae, Caryophyllaceae and Rosaceae, cf. non-endemics. In conclusion, chromosome duplication is more frequent and extensive in recent angiosperms, particularly young endemics, supporting the hypothesis of polyploidy as a key driver of neo-endemism. However, as young endemics may also be diploid, polyploidy is not an exclusive driver of neo-endemism.
Three Year Outcomes of Intravitreal Ranibizumab and Aflibercept Treatment of Patients with Diabetic Macular Edema in a Real-World Setting
Authors: Akbaş Yusuf Berk , Alagöz Cengiz , Çakmak Semih , Demir Gökhan , Alagöz Neşe , Artunay Özgür
Published: June 2021

PurposeTo evaluate and compare the functional and anatomical outcomes of intravitreal ranibizumab (IVR) and aflibercept (IVA) treatments in patients with diabetic macular edema (DME).MethodsFour hundred three eyes of 235 naïve patients who underwent IVR or IVA treatment for diabetic macular edema and followed up to 36 months included in this retrospective, real-life study. All patients underwent 3 loading doses and followed up with a PRN regimen. Best corrected visual acuity (BCVA) and central macular thickness (CMT) were measured at baseline, year 1, 2 and 3. ResultsThere were 198 eyes in IVR group and 205 eyes in IVA group. The changes in mean BCVA were 0.09±0.32 vs 0.17±0.41 logMAR (p=0.042) at year 1, 0.09±0.37 vs 0.12±0.45 logMAR (p=0.512) at year 2 and 0.13± 0.36 vs 0.15±0.48 logMAR (p=0.824) at year 3 in IVA and IVR groups, respectively. The baseline mean BCVA were lower (p=0.004) in IVA group. In terms of CMT changes, there were no differences between groups. Conclusion﻿At year 1, change in mean BCVA was statistically significantly higher in IVA group, however this difference did not persist at year 2 and 3. Both ranibizumab and aflibercept treatments achieved a good long-term visual and anatomical response in DME patients.
Workflow for robust Scholte and Love waves phase-velocity estimation from small aperture Ocean Bottom Seismometer arrays in Lake Lucerne: deployment, location, orientation, and clock error correction
Authors: Lontsi Agostiny Marrios , Shynkarenko Anastasiia , Kremer Katrina , Hobiger Manuel , Bergamo Paolo , Fabbri Stefano C. , Anselmetti Flavio S. , Fäh Donat
Published: June 2021

The phase-velocity dispersion curve (DC) is an important characteristic of the propagation of surface waves in sedimentary environments. Although the procedure for DC estimation in onshore environments using ambient vibration recordings is well established, the DC estimation in offshore environments using arrays of Ocean Bottom Seismometers (OBS) presents three main challenges. These are the localization, the orientation of the OBS horizontal components, and the clock error. Here, we concentrate on the workflow for a robust estimation of the phase-velocity dispersion curves from small aperture OBS array measurements in Lake Lucerne (Switzerland). OBS array campaigns were performed between 2018 and 2020 using arrays with a maximum aperture of 679 m at a maximum water depth of 81 m. The challenges related to the OBS location on the lake floor were addressed by combining the multibeam bathymetry map and the backscatter image for the investigated site with the differential GPS coordinates of the OBS at recovery. The OBS measurements were complemented by airgun surveys. Airgun data were first used to estimate the misorientation of the horizontal components of the OBS and second to estimate the clock error. Finally, we use two array processing methods, namely the three-component high-resolution frequency-wavenumber and the interferometric multichannel analysis of surface waves, to estimate the dispersion characteristics of the propagating surface waves for one of the array sites. We clearly observe the phase-velocity dispersion curve branches for Scholte and Love waves in the frequency range between 1.2 and 3.2 Hz for both array processing techniques.
Urinary Phenols and Parabens Metabolites with Cardiovascular Disease in United States Adult
Authors: Yin Ting , Zhu Xu , Cheang Iokfai , Zhou Yufei , Liao Shengen , Lu Xinyi , Zhou Yanli , Yao Wenming , Li Xinli , Zhang Haifeng
Published: June 2021

Environmental health has begun to examine the effects of higher-order chemical combinations. The current literature lacks studies exploring associations between multiple organic chemicals mixture and cardiometabolic disease (CVD). This study aimed to evaluate associations between urinary phenol and paraben metabolites and total and individual CVD among a nationally representative sample of adults in the US. This cross-sectional study analyzed 7 urinary chemicals detected among the general population from the 2005–2016 National Health and Nutrition Examination Survey (NHANES, n = 10,428). Multivariate logistic regression and weighted quantile sum (WQS) regression were applied to examine relationships between phenol and paraben metabolites, alone and combined, and total and individual CVD prevalence. WQS regression showed that phenol and paraben indices were independently correlated with total CVD (adjusted odds ratios [OR]: 1.16; 95% confidence interval [CI]:1.06–1.28; P = 0.002), angina (adjusted OR: 1.30; 95% CI: 1.07–1.59; P = 0.009), and heart attack (adjusted OR: 1.30; 95% CI: 1.12–1.51, P < 0.001). Urinary bisphenol A (URBPA, weight = 0.636) was the most heavily weighted component in the total CVD model. Compared with the lowest quartile, URBPA (OR: 1.52; 95% CI: 1.20–1.91; P = 0.001) levels in the highest quartile were independently associated with increased total CVD. Restricted cubic spline regression demonstrated positive correlations and non-linear associations between URBPA and both total CVD (P for nonlinearity = 0.032) and individual CVD (heart attack; P for nonlinearity = 0.031). Our findings suggested that high combined levels of phenols and parabens are associated with an increased CVD risk, with the URBPA contributing the highest risk.
Variation In The PRNP Gene Of Pere David’s Deer (Elaphurus Davidianus) May Impact Genetic Vulnerability To Chronic Wasting Disease
Authors: Perrin-Stowe Tolulope I.N. , Ishida Yasuko , Terrill Emily E. , Beetem Dan , Ryder Oliver A. , Novakofski Jan E. , Mateus-Pinilla Nohra E. , Roca Alfred L.
Published: June 2021

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy caused by prions that has spread across cervid species in North America since the 1960s and recently spread to cervids in Eurasia. The Association of Zoos and Aquariums (AZA) considers CWD to be of major concern for cervids in AZA-accredited facilities because of the indirect transmission risk of the disease and the impact of CWD regulatory protocols on captive breeding programs. Vulnerability to CWD is affected by variation in the PRNP gene that encodes the prion protein. We therefore sequenced PRNP in Pere David’s deer (Elaphurus davidianus), a species that was extinct in the wild for more than a century, and descends from ca. 11 founders. In 27 individuals, we detected two PRNP haplotypes, designated Elad1 (51 of 54 chromosomes) and Elad2 (3 of 54 chromosomes). The two haplotypes are separated by four single nucleotide polymorphisms (SNPs), three of which are non-synonymous. Both Elad1 and Elad2 have polymorphisms that in other cervid taxa are associated with reduced vulnerability to CWD. The two haplotypes are more similar in sequence to PRNP in other cervids than to each other. This suggests that PRNP in cervids may have been under long-term balancing selection, as has been shown for PRNP in non-cervid taxa, and which could account for the presence of multiple haplotypes among founders. There may be a fitness benefit in maintaining both PRNP haplotypes in the species because variation in the prion amino acid sequence can limit transmission of CWD.
The Cold Rolling Load Distribution of the Nuclear Power Zirconium Alloy Based on the Self-adaptive Particle Swarm Optimization Algorithm
Authors: Yuan Cao , Cao Jianguo , Tao Wang , Leilei Wang , Fang Li , Qian-qian Luo , Peng-fei Zhang
Published: June 2021

Aiming at the problem of load distribution during multi-pass cold rolling of nuclear zirconium alloy strip, the load distribution model with good shape is established by the self-adaptive particle swarm optimization algorithm (SAPSO), considering the main constraint conditions including rolling force, reduction and torque in cold rolling process. Based on the penalty function method transforming the constraint problem into the unconstrained problem, the particle swarm optimization algorithm with adaptive inertia weight factor optimized the load distribution model is developed to improve the local search ability of the particle swarm optimization algorithm. Compared with the existing nuclear zirconium alloy industrial schedule, the simulation results of load distribution based on the SAPSO can keep good shape in multi-pass cold rolling process with the high prediction accuracy. The industrial experiments demonstrate that the proportional crown difference value is consistent, the plate shape flatness is good.
The Potential Protective Effect of Spirulina Nanoparticles Against Ehrlich Solid Tumor Bearing Mice Induced Liver Toxicity, Tumor Markers, DNA Fragmentation, Oxidative Stress and Monooxygenase Variations
Authors: Alheeti Omar NK , Elsamie Gihan H Abd , El-Banna Sabah G , Tousson Ehab
Published: June 2021

Ehrlich solid tumor (EST) is a spontaneous murine mammary adenocarcinoma, undifferentiated, making mainly beneficial for tumors studies. The current research aim to describe the antineoplastic activity of spirulina nanoparticles extract (SP NPs) against EST induced alteration in liver functions, oxidative stress, tumor markers, monooxygenase and DNA damage in female mice. 40 female mice were arbitrarily doled out into 4 gatherings (1st, Control; 2nd, SP NPs; 3rd, EST; 4th, EST + SP NPs). Results revealed significant elevation in the levels of AST, ALT, GGT, ALP, AFP, CEA, DNA damage; thiobarbituric acid reactive substances (TBARS), and glutathione peroxidase (GPx) in liver homogenate and depletions in the levels of albumin, total proteins, cytochromes (CYP450 & cyt b5), reduced glutathione (GSH), glutathione reductase (GR), glutathione S transferase (GST) and superoxide dismutase (SOD) activity in liver homogenate compared to control. EST Treatment with SP NPs (EST + SP NPs) improved and modulates these variations in liver functions, tumor markers, DNA damage, cytochromes, enzymatic and non-enzymatic, and oxidative stress as compared to mice bearing EST. These results suggest that SP NPs may have hepatic protective, antioxidant, and anti-cancer properties; in addition to inhibition of the EST development, and liver DNA damage induced by EST.
Possible Causes of Gender Differences in COVID-19 Infection Rate and Mortality
Authors: liu can , Hu Renwang , Yu Yongqiang
Published: June 2021

Purpose To study the causes of gender differences in infection rate and mortality of COVID-19.Methods According to the confirmed results so far, it was found that the expression of ACE2, TMPRSS2, NRP1 and FURIN genes were related to SARS-COV-2 virus infected cells; CD4, CD8 and NLRP3 genes were related to human immunological response; NSP1 gene was related to immunosuppression; IL6 (IL-6), IFNG (IFN-γ) and TNF (TNF-α) genes were related to the occurrence of cytokine storm. The differential expression of these genes between male and female were analyzed in normal and tumor patients, and further analyzed in different locations of normal and tumor tissues to find out risk factors affecting the infection rate and mortality. Results In our study, we identified that in the lung tissue, the expression level of ACE2, TMPRSS2, NRP1 and FURIN genes in male patients were higher than those in female patients. In all normal tissues of patients: NRP1, FURIN and NSP1 genes were significantly higher expressed in female. In all tumor tissues of patients: ACE2, FURIN and IL-6 genes were significantly higher expressed in male, while TMPRSS2, CD4, CD8, NLRP3, NSP1 and TNF genes were significantly higher expressed in female.Conclusions The significant differential expression of SARS-COV-2 receptor related genes and immune response related genes between male and female patients may be the reason for the difference in COVID-19 infection rate and mortality. The expression of COVID-19-related genes in normal and tumor patients were also significantly different, so clinical treatment should be treated differently.