bluuebunny/crossref_metadata_2025 huggingface dataset:
Utility of Sequential Organ Failure Assessment Score in Prognosticating sick Children in Paediatric Intensive care Unit
Authors: Kafle Raju , Sanjeev Shah , Binod Kumar Gupta
Published: December 2022

Introduction: There are number of scoring systems to assess the morbidity and mortality of sick children in intensive care unit. Out of these scoring systems our study was designed to look for the utility of Sequential Organ Failure Assessment (SOFA) score which is less time consuming and simple to apply as a predictor of mortality in sick children admitted in Paediatric Intensive Care Unit (PICU).
Methods: This was a prospective observational study done in PICU of Universal College of Medical Sciences, Bhairahawa, Nepal. Recruited patients were all critically sick children above one year who stayed in hospital above 72 hours and underwent all necessary evaluation, and were followed up until they were discharged or deceased. Initial SOFA score was calculated within 24 hours of admission (SOFA T0) and again calculated after 72 hours (SOFA T72). Delta SOFA score was calculated as the change in SOFA scores over 72 hours (SOFA T0 - SOFA T72). The primary outcome was in-hospital mortality.
Results: When compared to outcome, the non survivors had high mean initial SOFA (T0) 11.51 ± ences ec ing 3.001 (P < 0.001), mean SOFA after 72 hours (T72) was 15.51 ± 4.026 (P < 0.001) and mean delta SOFA (T0-T72) was 4.58 ± 2.59 (P = 0.166) as compared to survivors. Delta SOFA was not significantly associated with outcome (P = 0.166). The initial SOFA score T0 > / = 11 predicted a mortality of 70.90% and SOFA T72 score of >/=15 predicted a mortality of 81.60% but delta sofa >/= 4 predicts a mortality of only 43.60%. Area under receiver operating characteristic (ROC) curve for SOFA TO was 0.769, for SOFA T72 was 0.890 and for delta SOFA was 0.604 and thus, showing excellent discriminative power for SOFA 72 for predicting mortality.
Conclusions: The SOFA score demonstrated fair to good accuracy for predicting mortality when applied to sick children > 1 year admitted in PICU. Our study showed both initial SOFA T0 and SOFA at 72 hours predict mortality with good accuracy but SOFA at 72 hours is a better predictor of mortality as compared to initial and delta SOFA scores.
Fighting pandemics with enhanced risk communication: Messages, compliance and vulnerability during the COVID-19 outbreak (PAN-FIGHT): Summarised findings and recommendations
Authors: Scharffscher Kristin Sørung
Published: December 2022

This report is a product of the research collaboration project Fighting pandemics with enhanced risk communication: Messages, compliance and vulnerability during the COVID-19 outbreak (PAN-FIGHT). Project initiator and coordinator is The University of Stavanger, and main project partner institutions are the University of Geneva, Mid-Sweden University, King’s College London and DIALOGIK Germany. PAN-FIGHT is funded by the Research Council of Norway and has run from August 2020 to September 2022. Summarised findings and recommendations has been written and edited by Kristin S. Scharffscher with contributions from Ole Andreas Engen, Claudia Morsut, Mathilde Bourrier, Emma Comrie, Farnaz Mahdavian, Michael Deml, Evangelia Petridou, Jörgen Sparf, Frederic E. Bouder, Matan Shapiro, Darrick Evensen, George Warren, Sanjana Arora, Hilda Mjøll Gunnarsdottir, Susanna Öhman, Siri Wiig and Olena Koval.
PROBLEMS AND PROSPECTS OF THE DEVELOPMENT OF TAX AUDIT AS A MEANS OF REDUCING TAX RISKS
Authors: Bezdolnaya Tatyana , Neshchadimova Tatyana
Published: December 2022

Introduction. Today, tax audit is a tool that provides fully and effectively min-imizing tax risks and optimizing taxes in an organization. An urgent problem of tax audit constitutes the identification of key areas of audit, which ensure the effective and rational conduct of tax audit. The purpose of the article is a comprehensive study of the problem of tax audit development in Russia. Methodology. In the study, the key problems that hinder the potential and development of tax audit are presented in a sys-tematic way, using methods of logical and statistical analysis. The article analyzes the results of desk and field inspections in the Russian Federation over the past three years. The number of revealed tax violations as a result of tax audits is determined. Results. Planning is one of the mandatory stages of a tax audit, which includes the def-inition of strategy, tactics, scope of work and the development of a tax audit program. The article presents the results of measures to improve the activities of auditors, the stages of planning a comprehensive tax audit, and develops optimization methods for VAT. Conclusions. It is concluded that implementing a tax audit requires the devel-opment of practical recommendations for improving the activities of auditors and au-dit organizations, which will reduce the risks of tax audits and claims from the tax au-thorities, building the right strategy for the organization.
ANALYTICAL TOOLS TO JUSTIFY INVESTMENT DECISIONS
Authors: Uryadova Tatyana , Leshcheva Marina
Published: December 2022

Introduction. The purpose of the study is to develop a methodology for justifying the choice of an investment project using a rating comprehensive assessment. The tasks of the study include updating the issues of analytical support of the investment project at all stages of its passage: from the development stage to the stage of implementation and the formation of economic, social, budgetary and other types of effect. Methodology. The study includes methods of scientific knowledge, such as detail and generalization, analysis, comparison, as well as a ranking method for assessing the choice of an investment project option, graphic for visualizing data. Results. A critical analysis of the existing methodological apparatus was carried out. The list of analytical indicators and tools was supplemented; the model range of factor analysis was expanded to obtain a comprehensive view of the long-term results of the investment project. An algorithm for the analytical substantiation of the choice of an investment decision using the methods of ranking and constructing radial diagrams was proposed. Conclusions. The practical application of the proposed procedures contributes to obtaining the most comprehensive assessment of the investment project, taking into account the multidirectional effects of its implementation, which means a deeper study of the analytical justification for its adoption and increasing investment attractiveness.
Pelatihan Pembuatan Poster Edukasi Dan Koleksi Museum Bagi Anggota Ikatan Pemandu Museum Indonesia (IPMI)
Authors: Yusmawati Yusmawati , Kusumawati Nina , Himawan Sultan , Wulandari Sri
Published: December 2022

Museums are one of the tourist destinations, especially educational and cultural tourism for the community. All resources in the museum including museum guides have an important role. In addition to being a guide, museum guide, and providing services for visitors, museum guides must also have other skills in communicating material or all things in the museum, including communicating in the form of posters that can be published. For two years, the world has been hit by the COVID-19 pandemic, and Indonesia is no exception. This pandemic has had a wide impact on all sectors of people's lives, including education and tourism. In 2022, the Ministry of Tourism and Creative Economy begins to launch a program to revive the slumped tourism industry. The Indonesian Museum Guides Association (IPMI) as a unifying forum and communication between museum guides in Indonesia welcomed this. One of them is by synergizing with Bina Sarana Informatika University in community service activities. In this activity, the lecturers who are members of the community service group help partners to provide training on making educational posters and museum collections for museum guides. This method of implementing Community Service activities is carried out online, through the zoom meeting application, due to the current pandemic situation in PPKM Level 3 status, so mass gathering in large numbers is not possible. The outputs of this activity include press releases and questionnaire results from both partners and participants.
APPLICATION OF INNOVATIVE TECHNOLOGIES DURING TRAINING OF TECHNICAL AND TACTICAL ACTIONS OF FOOTBALL STUDENTS
Authors: Bilokon V. , Anikеіenko L.
Published: December 2022

The article reveals the meaning and importance of using innovative technologies during the training of technical and tactical actions of football players. It was found that one of the main criteria for the development potential of modern society is good health and a high level of physical fitness. It was determined that training and comprehensive training of professional football players of a new quality is possible only with the help of modern methods based on the latest advances in information technology. Thus, the introduction of modern innovative technologies into the education system, which ensure further improvement of the educational process, technical and tactical training of football students, is of great importance. It has been established that the level of playing skill in football is based on the stability and variability of technical and tactical techniques. Reforms carried out in the system of higher education deeply affected the process of physical education of student youth. The search for ways to increase its effectiveness is the object of constant attention of many researchers. In addition, the process of physical education of students has its own characteristics due to the impact on it of various external and internal factors that determine the target orientation, the selection of the content of educational material, the design of organizational, methodical and material infrastructure. Most researchers associate the purpose of physical education and sports training with the formation of the physical culture of the student's personality.
THE INFLUENCE OF SWIMMING CLASSES ON IMPROVING THE HEALTH OF STUDENT YOUTH
Authors: Dakal N.
Published: December 2022

The impact of swimming on improving the health of young students. The article reveals the impact of swimming on improving the health of students in higher education. It is established that among the various areas of improving the health and quality of life of young people, especially students, swimming classes stand out. It should be noted that a comprehensive solution to the problems of organizing and conducting swimming lessons with students will improve the quality of life and basic indicators of student health.

It is determined that swimming lessons have a positive effect on the indicators of objective health of student youth, which is manifested in the normalization of their cardiovascular system. They characterize in detail the qualitative implementation of educational, professional and applied, health and hygienic, therapeutic and preventive and sports and pedagogical influences of swimming facilities on people of different ages, taking into account their anatomical, morphological, functional and gender differences.

The author focuses on the level and degree of formation of swimming skills and considers it necessary to adjust state tests and programs for physical education of different groups of the population. At the same time, this approach made it possible to establish the dominant aspects of the formation of swimming skills for different age groups.

In addition, the author highlights negative organizational phenomena that do not allow timely and reliable formation of vital skills of safe movement on water in a person. The variety of opportunities for swimming, its recreational and recreational value makes this sport one of the most popular among students.
PEDAGOGICAL CONTROL AND ITS SIGNIFICANCE IN CONTROLLING SPEED-POWER MOVEMENTS IN STUDENT WEIGHTLIFTERS
Authors: Sobolenko A. , Luskan О. , Martinov Yu.
Published: December 2022

The article reveals the importance of pedagogical control in the management of speed-power movements in student weightlifters. It is assumed that the effectiveness of technical techniques should be evaluated based on the registration of a limited number of basic biomechanical characteristics of movement. Applying a system of internal reference points for an athlete, in combination with hardware techniques, it is possible to develop a control technique acceptable for use at all stages of training athletes for important competitions.

The selection of rational pedagogical influences and their reduction into an algorithmized methodology, the use of a system of urgent information on the effectiveness of exercises will contribute to a targeted change in movement skills, which will speed up the training process of weightlifters and improve the system for evaluating their achievements. When building a specific methodology, the development of the structure and content of algorithmized pedagogical influences acquires great importance. This may indicate an unformed need for physical exercise. Which, in turn, indicates a low level of motivation for physical education. Currently, one of the urgent problems is the effective organization of physical education classes for young people in universities. The main component for the successful implementation of any activity, including physical culture and sports, is motivation. Taking into account psychological factors that contribute to the perception and adequate processing of information, the use of the features of the formation of "meaningful", "target", "operational" attitudes will help speed up the learning process. And the selection of auxiliary exercises, determination of their sequence, will contribute to consolidation of rational motor skills.
Development of playing intelligence as the basis of the process of teaching technical and tactical actions to young football players of preschool age
Authors: Bondarenko S. , Savchenko V. , Sklanichenko S.
Published: December 2022

Relevance: The backwardness of domestic football prompts a critical analysis of the entire system of training football players and the search for new, innovative approaches to the educational and training process.

Purpose: To theoretically and experimentally justify a new approach to the process of teaching technical and tactical actions of children 6-7 years old based on the development of game intelligence.

Material and methods: Young football players (n=26) took part in the experiment. We studied indicators that, in our opinion, are components of gaming intelligence (physical, aesthetic and spatial intelligence). A battery of motor and mental tests was used.

Results: based on the theory of H. Gardner, researches of M. Bernshtein, V. Platonov formulated a new concept - "game intelligence of a football player", which is considered as a synthesis of manifestations of bodily-kinesthetic and spatial types of player's intelligence. According to the results of the one-year experiment, the advantage of the holistic process of teaching technical and tactical actions based on the use of specially developed simulation games and game tasks was proven. Thus, at the end of the study, the experimental group had a statistically significant advantage in manifestations of bodily- kinesthetic intelligence, in particular, in the Lyakh test and the Pavlik-Mykota test. The advantage in terms of spatial intelligence was as follows: in the Kern- Irasik test, the Bartashnikov test, and the Venger test.

Conclusions: the results of the conducted experiment provide certain grounds for making changes in the methodology of teaching technical and tactical actions based on the accented application of developed simulation games and game tasks.
The estimation of health and recreational activities optimization options of students of pedagogical colleges
Authors: Buhaichuk N. , Bielikova N.
Published: December 2022

Nowadays the problem of developing and implementing qualitatively new and modern theoretical foundations and practical approaches to the problem of increasing the motor activity of young people through their active involvement in health and recreational activities requires a special attention. The article defines the health and recreation activities orientation of students of pedagogical colleges and outlines the ways of its optimization. It was established that many young people do not lead a healthy lifestyle (15%) or do not always (62%); the majority (44%) determined that the main motive for attending sports classes is to get a good mark for exam; 77% of respondents do not engage in additional physical activity in extra time; however, 72% of respondents want to improve their level of physical fitness, and 44% of students claim that they have a lack of knowledge to lead a healthy lifestyle. Ways to optimize health and recreational activities of students were determined: actualization of the system of significant needs, motives and interests for didactic content of health and recreation classes; implementation of innovative approaches to the quality of teaching sports educational components, which will stimulate the need for self-education and self-improvement of health-saving competence, support and implementation of own innovations in recreational and health activities; creation of conditions for satisfying the needs of students in promoting health, physical and mental development by means of increasing the motor activity through the implementation of health and recreational technologies in extra time; development of students’ individual skills and abilities in specific types of health and recreational activities, experience formation of motor activity and its realization; formation in the minds of student youth a particular way to a healthy lifestyle that will encourage to use health and recreational activities and will be aimed at developing and promoting of health.
The influence of training with free-fight means on motor skills, sensory functioning and quality of life of a child with autism (unique case)
Authors: Musiyenko Olena , Muminov Alisher , Artiukh Volodymyr
Published: December 2022

The motor sphere of children with autism is characterized by the presence of stereotyped movements, difficulties in the formation of objective actions and household skills, and violations of fine and gross motor skills.

The aim of the work was to establish the influence of adaptive training with elements of free-fight on the development of motor skills, sensory profile and quality of life of a child with autism.

A 12-year-old boy A. with a diagnosis of childhood autism, social maladaptation (disability subgroup A) was chosen for the experiment. The child does not speak, cannot read or write, has impaired coordination of movements (walking on tiptoes, motor stereotypies, motor disinhibition), insufficient understanding of language. Somatically, the boy is healthy, loves motor activity.

An assessment of the child's sensory functioning was carried out according to the Short Sensory Profile method, developed and recognized by The Psychological Corporation (USA), a survey of parents about the child's quality of life before the start of training and after a forced break in training, in addition, an assessment of the quality of direct blows with the hand and foot was carried out punching bags at each session.

During the research period, the boy A. performed, under the guidance of a coach, exercises for coordination of movements ("obstacle course"), interaction with the coach (gymnastic exercises, various available games with a ball), exercises for developing the strength of various muscle groups (work with "Bulgarian bag", dumbbells) and special free-fight exercises (hits with hands and feet on punching bags and a dummy).

A significant improvement of the child's sensory functioning was established, namely all types of sensitivity, except auditory filtering and sensitivity to taste and smell. The child's parents noted a significant increase in the quality of life of both the boy himself and the entire family. Significant progress was observed in learning the technique and the success of the boy's performance of special free-fight exercises. Adaptive training with elements of free fight served as a significant sensory stimulus for a child with autism, contributed to the learning of motor skills, and improved the quality of life of the family.
Influence technique of the take-off phase on the flight phase of the hop in the female triple jump among elite athletes
Authors: Rozhkov V. , Taran L. , Okun D. , Riadova L. , Shutieiev V.
Published: December 2022

The article discusses relationships between biomechanical parameters techniques take-off phase and flight phase of the hop among the qualified women specializing in triple jump. As a result of correlation analyses was determined that if research women faster put leg on the support, they will have more initial velocity of the total center of mass of the bodies r=0,955, reducing values dilution of the hips during flight phase of the hop r=-0,773, decrease time of flight phase of the hop r=-0,788 and increases long of the hop r=0,793.

If athletes spend more time on take-off phase, they will have more initial velocity of the total center of mass of the bodies r=0,770.

Take-off angle influences on such parameter’s techniques of flight phase of the hop as: velocity of the total center of mass of the body’s r=0,721, angle between thighs r=-0,722. The correlation coefficient showed that if research athletes have more take-off angle they will have more velocity of the total center mass of the body and less angle between thighs during flight phase of the hop.

Determined direct correlation between angle between hop at the take-off phase and angle between hop at the flight phase of the hop r=0,717. If women athletes have more angles between thighs at the take-off phase, they will have more angles between thighs at flight phase of the hop.

Determined that for effective implementation phase of the hop during techniques trainings should more time spend on improvement angles parameters of the take-off, increase the velocity of the put leg on support, and less time of the take-off phase.
Diagnóstico prenatal de neuroblastoma quístico suprarrenal fetal
Authors: Torres-Cepeda Duly , Rondon-Tapia Martha , Reyna-Villasmil Eduardo
Published: December 2022

El neuroblastoma es un tumor embrionario que surge de los neuroblastos (células simpáticas pluripotentes) y es la lesión sólida maligna más común de la infancia. Estos tumores pueden aparecer en cualquier sitio del sistema nervioso simpático fetal, pero la glándula suprarrenal está afectada en el 90% de los casos durante el periodo prenatal. Los neuroblastomas quísticos comprenden alrededor del 50% de todos los casos diagnosticados en fetos y su frecuencia es aún mayor en el periodo posnatal. La ecografía puede utilizarse para determinar el tamaño, localización y características ecográficas del tumor. La resonancia magnética fetal puede ser útil para la estadificación y la evaluación de las metástasis. El manejo del embarazo es expectante y rara vez está indicada la interrupción del embarazo. Se presenta un caso de diagnóstico prenatal de neuroblastoma quístico suprarrenal fetal.
INTELLECTUAL PROPERTY LICENSES AND ASSIGNMENTS IN IRANIAN LAW: FROM TRADITIONAL RULES OF CONTRACT LAW TO NEW NECESSITIES OF MODERNISATION
Authors: Ghabooli Dorafshan Sayyed Mohammad Hadi , Sayyed Mohammad Mahdi Ghabooli Dorafshan  , Mostafa Bakhtiarvand
Published: December 2022

Assignments and licenses of intellectual property rights have become very common and important in the Iranian economy. Due to this development, the legal system needed to undergo reforms to cater to the specific characteristics of these types of contracts. To achieve this, the Iranian legislator has attempted to provide a number of articles in the main laws concerning intellectual property agreements. Two bills concerning industrial property and literary and artistic property have been drafted which include several provisions in this regard. This descriptive-analytical article intends to introduce licenses and assignments of intellectual property rights in Iran and explain the rules applicable to them in order to provide a basis for further studies on this topic. The findings of this study show that the attempts made by the Iranian legislators to regulate the assignments and licenses of intellectual property rights, although valuable, are not perfect and thus, it is recommended that specific provisions are enacted to deal with different aspects of those contracts. Until the legislator takes that step, where necessary, such contracts are governed by the general rules of traditional contracts which originate from the rich sources of Imamiah jurisprudence and legal doctrine.
EXTENDING INDONESIAN GASTRODIPLOMACY:BLENDING GEOGRAPHICAL INDICATION (GI) AND "KOPI INDONESIA"
Authors: Agus Trihartono  , Suyatno Ladiqi
Published: December 2022

This paper explores how coffee can contribute to the development of Indonesian gastro-diplomacy. Specifically, it investigates whether 5 incorporating Geographical Indication (GI) and the "Kopi Indonesia" (Indonesian Coffee) logo can strengthen Indonesia's nation brand (Bhinneka Tunggal Ika or "Unity in Diversity"). One of the goals of gastro-diplomacy is using food commodities as symbols of a specific identity. Thus far, Indonesian coffee branding has emphasised local identity over national identity. This paper argues that the coffee GI represents the uniqueness of coffee from regions within Indonesia and reflects the country's diversity. At the same time, the "Kopi Indonesia" brand places all of these regional variants under the same umbrella to make coffee products from Indonesia more recognisable on the global market. Unlike previous studies, which view GI and the Kopi Indonesia brand as solely related to marketing and protection of intellectual property rights,  this research shows that the unification of GIs and "Kopi Indonesia" has broader implications. Indonesia has utilised coffee as a tool of gastro-diplomacy, and the policies that the government has implemented around the coffee trade are tied to how the country wants to be perceived on the global stage.
ЗАХОДИ ЩОДО ЗАХИСТУ ПРИКАРПАТТЯ ВІД КАТАСТРОФІЧНИХ ПАВОДКІВ ШЛЯХОМ АНАЛІЗУ ЇХ ПРИЧИН ТА НАСЛІДКІВ У 2008 І 2020 РОКАХ
Authors: Михайлюк Роман Йосипович
Published: December 2022

01.01.2021 р. у складі ІФНТУНГ наказом ректора був створений Центр прогнозування та попередження техногенно-гідроекологічної небезпеки Прикарпаття. За останні роки на Прикарпатті катастрофічним характером відзначились два паводки: один 23-28 липня 2008 р., а другий 20-24 червня 2020 р. У статті розглянуті основні причини і наслідки катастрофічних паводків для Прикарпаття
Наслідками проходження катастрофічного паводка 2008 року стали – загибель 30 людей, підтоплення 41 тис. житлових будинків, 34 тис. га сільгоспугідь і руйнування 671 км автошляхів.
Стихія 2020 року на Прикарпатті мала більш раптовий характер, ніж повінь 2008 року. Протягом 20-23 червня на території області спостерігались інтенсивні опади у вигляді дощу. Тільки протягом цих двох днів випало 113 % місячної норми опадів. Зазначене спричинило різкий підйом води та сильну течію, особливо в гірських районах Прикарпаття.
Першопричиною надзвичайної ситуації можна вважати потужні дощові циклони, що переміщалися на територію України з Південного Заходу Європи, які спричинили сильні, подекуди дуже сильні зливові опади та формування катастрофічного дощового паводку в басейнах річок Дністер та Прут.
Одними із основних причин виникнення надзвичайних ситуацій стало здійснення неконтрольованої і не забезпеченої відповідними технологічними процесами вирубки лісових масивів на території Івано-Франківської області, несанкціоноване видобуванням піску та гравію у руслах річок і прибережних захисних смугах. Вагомою причиною стало також те, що за останні роки не було належно профінансовано жодної Державної програми щодо будівництва дамб і берегоукріплень річок, а також реконструкцій зливової каналізації, які експлуатуються вже досить тривалий термін без будь-яких оновлень.
На основі проведеного аналізу запропоновано заходи щодо зменшення негативних наслідків катастрофічних паводків.
Ultrasonographic Diagnosis of Left-sided Ovarian Torsion in a Twin Pregnancy at 24 weeks: A Case-Report
Authors:   Radiology Resident, Christus Muguerza Hospital Alta Especialidad, Monterrey, Nuevo León, México, López-Martínez Samuel Isaí , Sánchez-Valadez Jesús Gerardo ,   Radiologist, Christus Muguerza Hospital Alta Especialidad, Monterrey, Nuevo León, México, Tijerina-Torres María Andrea ,   Gynecology Resident, Christus Muguerza Hospital Conchita, Monterrey, Nuevo León, México, Melendez-Coral Rodrigo ,   Radiology Resident, Christus Muguerza Hospital Alta Especialidad, Monterrey, Nuevo León, México, Onofre-Castillo Javier Jesús ,   Radiologist, Christus Muguerza Hospital Alta Especialidad, Monterrey, Nuevo León, México
Published: December 2022

We describe a case report of ovarian torsion in a Korean-speaking woman with a 24-week twin pregnancy who attended a Spanish- and English-speaking institution. Ovarian torsion represents a diagnostic challenge for clinicians and radiologists because of its lack of pathognomonic symptoms and imaging findings. Ultrasonography may show unilateral ovarian enlargement without color Doppler flow and free fluid; however, clinical data should be mandatory for management decisions.
Clear Cell Variant of Squamous Cell Carcinoma of Skin: A Case Report and Review of the Literature
Authors: Bouanani Othmane , Elazzouzi Rajaa , Boulaadas Malik
Published: December 2022

Clear cell squamous cell carcinoma (SCC) is a rare variant of SCC of skin in which ultraviolet radiation has been suggested as possible etiology. We report a case of a 51-year-old male patient who presented with a 4 months history of a non-healing ulcer on the left side of his face. Histopathology and immunohistochemistry studies showed Clear cell variant of squamous cell carcinoma. This case showed an aggressive and bizarre clinical presentation but more report of cases are needed to have a better characterization of the clinical presentation and prognosis of this variant of this squamous cell carcinoma variant.
Cervico-facial Localization of Kimura’s Disease: Two Case Reports and Literature Review
Authors: El azzouzi Rajaa , Bouanani Othmane , Boulaadas Malik
Published: December 2022

Kimura’s disease is a very rare chronic inflammatory pathology of unknown etiology. It is actually an allergic or autoimmune reaction process involving blood vessels, lymphocytes and eosinophils. We report a first case of Kimura disease with cervical localization in a 37-year-old male Patient who saw the appearance of a swelling of the right parotid region evolving for 2 years. The patient benefited from a total right parotidectomy, the anatomopathological study of the tumoral piece came back in favor of Kimura’s disease. A second case of 20-year-old male Patient who saw the appearance of a 3 swelling of the right pre-auricular region, sub mental region and left cheek region evolving for 5 years. The patient underwent a biopsy of submental swelling, the anatomopathological study confirmed the diagnosis of Kimura’s disease. The patient benefited from a Corticosteroid therapy. The evolution was spectacular, with no recurrence at 12 months follow-up. Kimura’s disease is characterized clinically by subcutaneous nodules of cervicofacial localization, increased volume of salivary glands and satellite adenopathies. Its diagnosis is histological based on the identification of follicular hyperplasia with eosinophilic polynuclear abscesses. Treatment is surgical most often but in some cases Corticosteroid therapy is proposed.
Lateral Neck Malignant Cyst
Authors: Al Shaaibi Raya , Amani Al Saidi Smitha , Al Shamsi Salma
Published: December 2022

Branchial cysts are the most common lesions in lateral neck cysts. Rare branchial cysts are associated with malignant tumors metastatic from the thyroid gland. Occult thyroid papillary carcinomas often present as a solid mass in the lateral neck, with only a few cases revealing a branchial cyst as the initial manifestation.
PENGARUH PENGGUNAAN VIDEO PEMBELAJARAN TERHADAP KEMAMPUAN PEMECAHAN MASALAH KIMIA PESERTA DIDIK KELAS XDI SMA NEGERI 1 NITA
Authors: Yuliana Feliksia , Leto Kristina T. , Ndori Vinsensisus H.
Published: December 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh penggunaan media video pembelajaran terhadap kemampuan pemecahan masalah kimia peserta didik kelas X MIA SMA Negeri 1 Nita. Penelitian ini merupakan penelitian deskriptif kuantitatif yang dirancang dengan desainposttest-only control group. Populasi penelitian adalah kelas X SMA Negeri 1 Nita, sampel penelitian adalah kelas X MIA1 sebagai kelas kontrol tanpa menggunakan media pembelajaran, dan X MIA2 sebagai kelas eksperimen yang menggunakan video pembelajaran yang diambil menggunakan teknik random sampling dan proposal sampling. Teknik pengumpulan data penelitian menggunakan tes tertulis yang dilakukan setelah empat kali pertemuan. Alat pengambilan data dalam penelitian ini yaitusoal uraian kemampuan pemecahan masalah. Berdasarkan hasil penelitian, rata-rata kemampuan pemecahan posttest kelas eksperimen dan kelas kontrol masing-masing adalah 77,27 dan 57,19. Kemudian menggunakan uji chi kuadrat dan uji Fisher untuk menguji tingkat normalitas dan tingkat homogenitas data untuk hasil posttest kemampuan pemecahan masalah. Setelah data dianggap normal dan homogen, dilanjutkan dengan pengujian hipotesis menggunakan uji-t. Analisis ujihipotesis menghasilkan nilai thitung sebesar 5,795 dan ttabel sebesar 2,009 pada taraf signifikansi 5% dengan df 50. Hasil ini menunjukkan bahwa thitung> ttabel adalah 5,795 > 2,009, jadi H1diterima dan H0 ditolak. Dapat diputuskan bahwa penggunaan video pembelajaran berpengaruh signifikan terhadap kemampuan pemecahan masalah kimia peserta didik MIA kelas X SMA Negeri 1 Nita
THE RELATIONSHIP BETWEEN SIDE EFFECTS OF TUBERCULOSIS DRUG USE AND SGOT/SGPT VALUE OF INTENSIVE PHASE PATIENTS
Authors: Sabiti Farroh Bintang , Sa’dyah Nur Anna Chalimah
Published: December 2022

Tuberculosis is an infectious disease caused by the bacteria Mycobacterium Tuberculosis which has a rod shape and is acid-resistant. The prolonged consumption of anti-tuberculosis drugs can cause serious side effects. Side effects from the consumption of anti-tuberculosis drugs, namely the risk of hepatotoxicity, which is marked by an increase in the SGOT / SGPT value. This study aimed to determine the relationship between the duration of use, dosage and side effects of anti-tuberculosis drugs in tuberculosis patients, which had an effect on the SGOT / SGPT value at RSI Sultan Agung Semarang. This research is an analytical observational study with a cross-sectional design. The sample was 96 patients, and data collection was carried out in January-November 2020 at RSI Semarang. The instrument used in this study was patient medic record data. This study uses the Chi-Square test. The Chi-Square test results in 0.000 (p <0.05) so that it could be stated that there was a relationship between the use and side effects on the SGOT / SGPT value.
VALIDATION OF SPECTROPHOTOMETRIC METHOD TO QUANTIFY QUERCETIN IN THE IN VITRO DISSOLUTION STUDY OF SELF NANO-EMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS)
Authors: Muhtadi Wildan Khairi , Firmansyah Ferdy , Agustini Tiara Tri , Rahayu Pricillia , Fitriyanti Siti Arifah , Ulfa Rodhia
Published: December 2022

Quercetin possesses low solubility and decreases oral bioavailability. One way to increase the bioavailability of quercetin is by formulating a self-nanoemulsifying drug delivery system (SNEDDS). In vitro dissolution testing of SNEDDS needs to be carried out using a validated analytical method. This study aims to validate the quercetin analytical method in in vitro dissolution testing. Validation was carried out with two solvents, namely hydrochloric acid buffer pH 1.2 (HCl-1,2) and phosphate buffer pH 6.8 (PO-6.8). It tested some parameters, including linearity, detection limit (LoD), quantification limit (LoQ), accuracy, and precision. The quercetin calibration curve for both solvents has a value of r≥0.999. The LoD at HCl-1,2 and PO-6,8 were 0.26 ppm and 0.27 ppm, respectively. The LoQ of HCl-1,2 and PO-6,8 were 0.86 ppm and 0.91 ppm, respectively. The percentage recovery in both solvents was in the range of 80-110%. The relative standard deviation of the two solvents was less than 7.3%. The quercetin analytical method has been successfully validated as indicated by the results of linearity, detection limit, quantification limit, accuracy, and precision that met the requirements
Phytochemical Study and Biological Activities of Ceratonia siliqua L.
Authors: Sahnouni F. , Lehfa F.
Published: December 2022

The carob tree (Ceratonia siliqua L.) belongs to the legume family and is mainly cultivated in the Mediterranean. Ceratonia siliqua L. is a medicinal plant used in traditional Algerian medicine. Therefore, this study aims to analyze the phytochemical constituents, traditional uses, and pharmacological activities of Ceratonia siliqua. Indeed, certain studies and research on pods and leaves of carob have revealed the presence of a number of compounds, including large amounts of carbohydrates, dietary fiber, minerals, polyphenols, flavonoids, and low amounts of protein and lipids. The secondary metabolite profile of carob extracts includes a matrix rich in polyphenols which is responsible for several biological effects and health attributes, namely, anticancer, antidiabetic, anti-inflammatory, antioxidant, antiulcer, anticonstipation, and antihyperlipidemic activities. So we finally concluded that carob had beneficial preventive and therapeutic properties.
‘To the Extremes of Asian Sensibility’
Authors: Ladeira Juliana Coelho de Souza
Published: December 2022

This article proposes a comprehensive and detailed approach to the reception of the Balinese performances and the performers’ stay at the International Colonial Exhibition of 1931, held in Vincennes, France. Thus, it analyses French sources, such as the daily press, specialised and literary magazines, photographs, films and sound recordings. As one of the most acknowledged attractions of the Exhibition, the Balinese group appeared extensively in the press. This ensemble of documents allowed us to understand that their performances’ favourable reception contributed considerably to creating a positive impression of Dutch colonisation and the progressive inclusion of Bali in the world's cartography.
Picturesque Savagery on Display
Authors: Ballestero Diego
Published: December 2022

This article discusses the importance of commercial exhibitions of Indigenous people in the development of anthropological practices in South America between the late nineteenth and early twentieth centuries. First, it examines the intrinsic links between commercial ventures based on the exhibition of Indigenous people and anthropological practices. These spaces of scientific popularisation allowed the anthropologists to economise the time, economic, material and human resources involved in an excursion to the field in the classic sense. The article then presents and examines the anthropometric, linguistic, photographic and musicological investigations that the German anthropologist Robert Lehmann-Nitsche (1872–1938) conducted between 1898 and 1904 on Selk'nam, Qom and Tehuelche groups exhibited in local and international commercial enterprises. Finally, through Lehmann-Nitsche's research, I explore of how European anthropologists profited from these commercial ventures for the study of indigenous people, the use of urban spaces for ‘fieldwork’ and their transformation into anthropological ‘laboratories’.
ESTUDO DE VIABILIDADE DA PRODUÇÃO DE BISCOITO FUNCIONAL DO TIPO COOKIES UTILIZANDO O RESÍDUO DA POLPA DE CAJU
Authors: Xavier Soraya Vanessa Alves , Câmara Ana Paula Costa , Macêdo Cláudia Souza
Published: December 2022

O Brasil é um dos maiores produtores de caju, e sua produção está concentrada na região Nordeste. O pedúnculo de caju é um fruto rico em vitaminas, fibras e minerais, e apenas cerca de 20% é aproveitado. Seu beneficiamento gera uma grande quantidade de resíduos referentes a fração fibrosa e película, que são geralmente utilizados para ração animal, ou descartados como lixo industrial, gerando problemas ambientais. Esse resíduo pode ser facilmente inserido na alimentação humana através do seu aproveitamento para a elaboração de subprodutos, principalmente na produção de biscoitos, que geralmente utiliza a casca do trigo ou aveia como fonte de fibras. Diante disso, este trabalho objetivou apresentar uma alternativa de aproveitamento e agregação de valor para o resíduo do pedúnculo de caju, com a elaboração de biscoitos tipo cookies adicionados de resíduos obtidos da produção da polpa de fruta. Para a obtenção de um projeto de fabricação em escala fabril, foi realizado um estudo das etapas do fluxograma de produção, com equipamentos necessários, cálculos para balanço de massa, tabela nutricional, análise econômica para o cálculo dos possíveis custos, determinação do preço final unitário, e sugestão de rotulagem para o produto. Foi considerado o custo zero na obtenção do resíduo do pedúnculo de caju, ao considerar um acordo feito com empresas produtoras de polpa de fruta para a retirada desse resíduo, já que seu destino seria o descarte. Os resultados demonstram uma análise satisfatória para a produção do produto sugerido, entregando ao mercado uma alternativa de biscoito tipo cookie saudável, com formulação única, composta por ingredientes com relevante teor de fibras, consciência ambiental, e preço competitivo. Palavras-Chave: inovação, resíduos, cookies, alimentos funcionais.
Experiencing Dengue as a Medical Student
Authors: Shrestha Shubham
Published: December 2022

Dengue is a disease which spreads by the bite of an infected Aedes mosquito. Reading about a disease in a textbook and experiencing it as a patient is a completely different thing. This article highlights the feeling of a medical student as a patient. It provides the reader with an idea of how Basic Science knowledge can be used for rational decision-making. Self- prescription of medication without consulting a doctor can be more harmful in many circumstances. We also need to be aware of the warning signs of Dengue virus infection.
Tourist loyalty dalam wisata kreatif agrowisata di kota Batu
Authors: Rahayu Siti , Ezar Brian Marcellino , Widjaja Fitri Novika
Published: December 2022

Penelitian ini membahas pengaruh experience quality, perceived value, tourist satisfaction terhadap tourist loyalty agrowisata di kota Batu. Penelitian dengan metode kuantitatif ini menggunakan 5 variabel yaitu experience quality, perceived value, tourist satisfaction, tourist motivation, dan tourist loyalty. Data primer penelitian diperoleh dari partisipasi 175 responden. Pengolahan data menggunakan SPSS 24 dan AMOS 22. Hasil penelitian menunjukan bahwa terdapat 4 hipotesis yang berpengaruh positif signifikan yaitu: experience quality berpengaruh terhadap tourist loyalty, tourist satisfaction berpengaruh terhadap tourist loyalty, experience quality berpengaruh terhadap perceived value, perceived value berpengaruh terhadap tourist satisfaction. Ada 2 hipotesis yang tidak signifikan yaitu pengaruh experience quality terhadap tourist satisfaction dan pengaruh perceived value terhadap tourist loyalty. Tourist motivation tidak memediasi experience quality terhadap tourist loyalty. Tourist motivation memediasi sempurna perceived value terhadap tourist loyalty. Tourist motivation memediasi sebagian tourist satisfaction terhadap tourist loyalty.
Peran Pembelajaran Organisasi Pada Pengaruh Kapabilitas Manajemen Pengetahuan Terhadap Kinerja Organisasi
Authors: Hidayat Taufik , Fikri Muhammad Ali , Kusuma Desta Rizky
Published: December 2022

Kapabilitas manajemen pengetahuan dan pembelajaran organisasi diyakini menjadi salah satu hal penting dalam meningkatkan kinerja organisasi. Meskipun demikian, hasil penelitian terdahulu menujukkan bahwa penelitian yang menganalisa pengaruh kapabilitas manajemen pengetahuan dan pembelajaran organisasi terhadap kinerja organisasi dapat dikatakan belum konsisten terutama ketika penelitian dilakukan di organisasi dengan skala kecil dan skala menengah. Oleh karena itu, penelitian ini bertujuan untuk menganalisa pengaruh kapabilitas manajemen pengetahuan terhadap kinerja organisasi yang dimediasi oleh pembelajaran organisasi. Metode olah data pada penelitian ini menggunakan SMART PLS 3.0 untuk menganalisis pengaruh pada masing-masing variabel. Data penelitian diperoleh melalui kuesioner yang disebarkan kepada pemimpin Usaha Mikro Kecil Menengah (UMKM) sektor perdagangan di Daerah Istimewa Yogyakarta dan diperoleh sampel sebanyak 89 responden. Hasil penelitian ini membuktikan bahwa kapabilitas manajemen pengetahuan memiliki pengaruh positif pada kinerja organisasi, kapabilitas manajemen pengetahuan berpengaruh positif pada pembelajaran organisasi, pembelajaran organisasi berpengaruh positif pada kinerja organisasi, dan pembelajaran organisasi memediasi pada pengaruh positif kapabilitas manajemen pengetahuan terhadap kinerja organisasi.
Faktor yang mempengaruhi keputusan penggunaan media streaming digital dimasa pandemi
Authors: Adiba Faela , Aviliani Aviliani , Yatna Chicilia Nova
Published: December 2022

Terjadinya pandemi covid-19 mengubah perilaku konsumen salah satunya cara konsumen mencari hiburan yang lebih memilih untuk menggunakan media hiburan  streaming agar lebih aman dari sisi kesehatan. Adanya perubahan pola perilaku tersebut menjadi suatu hal yang menarik untuk diteliti agar dapat membuat bisnis serupa bertahan dan terus diminati masyarakat. Oleh karena itu dirumuskan tujuan dari penelitian ini adalah untuk menganalisis pengaruh citra merek, pemasaran digital, dan harga terhadap keputusan penggunaan media streaming digital Netflix. Desain penelitian yang digunakan yaitu  penelitian kuantitatif dengan metode asosiatif. Metode survei digunakan sebagai cara untuk mengumpulkan data dari responden. Data dikumpulkan dari 100 responden dengan kriteria mereka yang berlangganan atau pernah berlangganan media streaming Netflix. Berdasarkan hasil penelitian ini menunjukan bahwa hanya citra merek yang memiliki pengaruh positif dan signifikan terhadap keputusan penggunaan media streaming digital Netflix.  Sementara itu pemasaran digital dan harga berpengaruh negatif terhadap keputusan penggunaan media streaming digital Netflix. Hal ini diharapkan dapat menjadi panduan bagi media streaming untuk melakukan kegiatan promosi terutama dimasa pandemi covid-19.
Sustainable Beauty: Pengaruh Eco-Label, Product Attributes, Perceived Consumer Effectiveness (PCE), dan Environmental Awareness terhadap Green Purchase Behavior
Authors: Djajadiwangsa Klareza Putri , Alversia Yeshika
Published: December 2022

Meningkatnya pencemaran lingkungan serta adanya urgensi untuk meningkatkan kepedulian lingkungan masyarakat Indonesia, menyebabkan perusahaan turut berkontribusi melalui penerapan green marketing. Sementara itu, sektor kosmetik di Indonesia saat ini sedang tumbuh signifikan. Green marketing juga turut diimplementasikan pada industri tersebut dengan munculnya berbagai merek kosmetik lokal yang mengusung konsep sustainable beauty. Gen Z menjadi salah satu faktor pendorong booming-nya industri kosmetik di Indonesia. Maka, pelaku bisnis sustainable beauty perlu mengetahui faktor-faktor yang dianggap berpengaruh terhadap green purchase behavior pada Gen Z. Penelitian ini mengidentifikasi beberapa faktor yang dianggap berpengaruh, melalui survei terhadap 335 responden yang dilakukan melalui kuesioner daring dan data dianalisis menggunakan Structural Equation Modelling (SEM). Hasil penelitian menunjukan bahwa faktor yang mempengaruhi green purchase behavior Gen Z terhadap produk green cosmetics merek lokal adalah eco-label, PCE, environmental attitude, dan ecological affection. Penelitian ini juga menunjukkan bahwa meningkatkan ecological affection dapat dilakukan baik secara langsung melalui PCE ataupun melalui environmental attitude terlebih dahulu.