A deworming field trial with ivermectin (MSD) in reindeer
Authors: Nordkvist M. , Christensson D. , Rehbinder C. 
Published: February 2013

<p>This paper is to be regarded as a follow-up under field conditions of Nordkvist et al. (1983) as far as ivermectin is concerned. 54 reindeer calves (29 males + 25 females), as far as possible of normal size, were selected November 15th, 1982 from a reindeer herd belonging to Maskaure sameby, Arvidsjaur. The calves were individually branded, by means of ear tags and weighed. 29 calves (15 males + 14 females) were treated with ivermectin (Ivomec 1% MSD) at a dose rate of 1 ml per calf (roughly corresponding to 200 meg ivermectin per kg body weight), subcutaneous injection. Remaining 25 calves (14 males + 11 females) served as untreated controls. The entire group of calves was then returned to the herd for free grazing during winter. During the winter 3 treated calves were found dead, all three of them had been suffering from keratoconjunctivitis. If any of the control animals had succumbed during the same time is not known. On April 21st, 1983 (approx. 150 days post treatment) 44 calves (24 treated + 20 controls) were weighed. 5 treated and 5 controls were randomly selected for slaughter. Carcasses and organs were thoroughly examined from a parasitological and, as far as lungs were concerned, pathological point of view. The efficacy of the treatment was 100(M&gt; or nearly 100% against Oedemagena tarandi, Cephenemyia trompe, Dictyocaulus viviparus, Elaphostrongylus rangiferi, and nematode eggs in faeces. The efficacy against gastrointestinal nematodes was, probably due to date of treatment, somewhat difficult to judge (Tab 1). A statistical analysis of the weight changes, relative to initial weights, (Tab. 2) supports the statements &mdash; that all animals had lost weight &mdash; that treated males had lost significantly less of their body weights than control males &mdash; That weight change of treated females did not differ significantly from that of control females &mdash; that the average weight loss of the entire treated group was significantly less than that of the control group.</p><p>Ett f&auml;ltavmaskningsf&ouml;rs&ouml;k med ivermectin (MSD) p&aring; renar.</p><p>Abstract in Swedish / Sammanfattning: 54 renkalvar (29 m + 25 f) s&aring;vitt mojligt av normal storlek, utvaldes den 25 november 1982 ur en renhjord tillhorig Maskaure sameby, Arjeplog. Kalvarna mdividm&aring;rktes med oronknappar och v&aring;gdes. Av dessa behandlades 29 kalvar (15 0*0" + 14 $9) med ivermectin (Ivomec, 1% MSD), 1 ml per kalv, subkutan injektion. Resterande 25 kalvar fungerade som obehandlade kontrolldjur. Den 21 april 1983 (efter 147 dagar) v&aring;gdes &aring;nyo 44 (24 behandlade + 20 kontroller) av de ursprungliga djuren. 5 renar i vardera gruppen slaktades och kropp och organ undersoktes parasitologiskt. Effekten av behandlingen var 100% eller n&aring;stintill mot Oedemagena tarandi, Cephenemyia trompe, Dictyocaulus viviparus, Elaphostrongulus rangiferi samt vad g&auml;llde forekomsten av nematod&aring;gg i tracken. Effekten p&aring; mag-tarmnematoder var, med h&aring;nsyn till behandlingstidpunkten, sv&aring;rbedomd. Effekten p&aring; trichostrongylida lopmagsmaskar var ocks&aring; sv&aring;rbedomd och diskuteras i texten. Den relativa forandringen av renarnas kroppsvikt, dvs forandringen i forh&aring;llande till ursprungsvikten, har ber&aring;knats och statistiskt bearbetats. Det kunde d&aring; konstateras &mdash; att samtliga renar hade forlorat i vikt &mdash; att den genomsnittliga viktforlusten hos de behandlade hankalvarna var signifikant l&aring;gre &aring;n hos de obehandlade hankalvarna &mdash; att den genomsnittliga viktforlusten hos de behandlade honkalvarna ime skiljde sig statistiskt fr&aring;n viktforlusten hos de obehandlade honkalvarna &mdash; att den genomsnittliga viktforlusten i hela den behandlade gruppen var signifikant lagre &aring;n i den obehandlade gruppen.</p><p>Kentt&auml;tutkimus porojen matokuurista Ivermectinill&auml; (MSD).</p><p>Abstract in Finnish / Yhteenveto: Arjeplogissa Maskauren lappalaiskyl&aring;&aring;n kuuluvasta porotokasta valittiin 25. marraskuuta 1982 54 porovasaa (29 m + 25 f) mik&aring;li mahdollista normaalikokoa. Vasat yksilomerkittiin korvanastoilla ja punnittiin. N&aring;ist&aring; k&aring;siteltiin 29 vasaa (15 m + 14 f) ivermectinill&aring; (Ivomec, 1 % MSD), 1 ml vasaa kohden, ruiskutcttuna nahan alle. Loput 25 vasaa toimivat k&aring;sittelem&aring;ttomin&aring; tarkkailuel&aring;imin&aring;. 21 huhtikuuta 1983 (147 p&aring;iv&aring;n j&aring;lkeen) punnittiin uudelleen 44 (24 k&aring;sitelty&aring; + 20 tarkkailuel&aring;int&aring;) alkuper&aring;isist&aring; el&aring;imist&aring;. Joka ryhm&aring;st&aring; teurastettiin 5 poroa ja ruho ja sis&aring;elimet tutkittiin parasitoloogisesti. K&aring;sittelyn vaikutus oli 100% tai l&aring;hes t&aring;ydellinen seuraavia kohtaan: Oedemagena tarandi, Cephenemyia trompe, Dictyocaulus viviparus, Elapohostrongylus rangiferi sek&aring; myoskin mit&aring; tulee matojen munien esiintymiseen sonnassa. Vaikutus maha - ja suolistomatoihin oli, k&aring;sittelyn ajankohdan huomioonottaen, vaikeasti ratkaistavissa. Vaikutus juoksutusmahoihin (trichostrongylida) oli myos vaikeasti ratkaistavissa ja siit&aring; keskustellaan tekstiss&aring;. Porojen ruhojen painon suhteellinen muutos, t.s. muutos suhteessa alkuper&aring;ispainoon on arvioitu ja tilastollisesti k&aring;sitelty. Voitiin silloin todeta &mdash; ett&aring; kaikki porot olivat kevcntyneet painossaan, &mdash; ett&aring; k&aring;siteltyjen urosvasojen keskim&aring;&aring;r&aring;inen painonv&aring;hennys oli merkitsev&aring;sti alhaisempi kuin k&aring;sittelem&aring;ttomien urosvasojen, &mdash; ett&aring; k&aring;siteltyjen naarasvasoien keskim&aring;&aring;r&aring;inen painonv&aring;hennys ei eronnut tilastollistesti k&aring;sittelem&aring;ttomien naarasvasojen painonv&aring;hennyksest&aring;, &mdash; ett&aring; koko k&aring;sitellyn ryhm&aring;n keskim&aring;&aring;r&aring;inen painonv&aring;hennys oli merkitsev&aring;sti alhaisempi kuin k&aring;sittelem&aring;ttom&aring;ss&aring; ryhm&aring;ss&aring;.</p>