bluuebunny/crossref_metadata_2025 huggingface dataset:
Wybrane zagadnienia związane z zaburzeniami zdrowia psychicznego i seksualnego w medycynie rodzinnej na przykładzie zespołu Gansera
Authors: Rechenek-Białkowska Marta , Jarząbek-Bielecka Grażyna
Published: February 2024

In the family doctor's practice, there are patients with mood disorders (depressive episodes), neurotic disorders (hypochondriac disorders, generalized and mixed anxiety disorders) and insomnia as well as with comorbidities (e.g. asthma, diabetes, heart disease, Alzheimer's disease). Each case in the diagnostic and treatment process requires the cooperation of a family doctor with a psychiatrist. The aspects of psychotherapy are also important; used in patients with mood and neurotic disorders: cognitive-behavioral and integrative psychotherapy. A difficult example of such a problem is Ganser's syndrome, which is also known as pseudo-dementia. It is considered a manifestation of dissociative disorders. Affected patients may show complete amnesia. These patients may also be unable to perform the simplest tasks. There are suggestions that the Ganser syndrome may be an attempt at simulation in a particularly difficult life situation. Symptoms of Ganser syndrome include sudden problems with carrying out everyday activities or answering the simplest questions.
Wybrane zagadnienia związane z możliwymi współwystępującymi przyczynami bólu głowy u kobiet z zespołem napięcia przedmiesiączkowego
Authors: Luwański Dawid , Plagens-Rotman Katarzyna , Kaczmarek Ada , Warchoł Emilia , Pisarska-Krawczyk Magdalena , Bielecki Marek , Opydo-Szymaczek Justyna , Jarząbek-Bielecka Grażyna
Published: February 2024

Headache, an almost universal human experience, is one of the most common ailments encountered in medicine. Headaches occur as much as three times more often in women than in men, much of which is related to premenstrual syndrome. The most common causes of headaches include: fatigue, strong emotional stress, problems with cerebral circulation, hormonal fluctuations, disturbed metabolism and vascular abnormalities. Uncharacteristic headaches may appear as a consequence of a particular lifestyle (e.g. smoking, alcohol abuse) or genetic factors. Recurrent headaches are most often associated with migraine. However, in the practice of a family doctor and in gynecological practice, it is worth remembering that these troublesome ailments can also be caused by dental or laryngological problems. Each recurring headache requires extended diagnostics, including neuroimaging, including magnetic resonance (MR) and computed tomography (CT), but diagnostics and consultations: dental or laryngological are also important.
The use of impedance audiometry in the diagnosis of children in the 6-month period in the Department of Pediatric Otolaryngology of the Medical University of Warsaw
Authors: Kawałko Aleksandra , Rigall Bartosz , Zawadzka-Głos Lidia
Published: February 2024

Introduction. Impedance audiometry is one of the best objective tests available to assess the function of the middle ear. It can be performed in patients of any age. Based on the results of impedance audiometry, you can draw the first conclusions about the condition of the middle ear and further diagnostics. Aim. The aim of the study was a retrospective assessment of the results of impedance audiometry carried out over a period of 6 months among children staying in the Department of Pediatric Otolaryngology of the Pediatric Clinical Hospital in Warsaw. Material and methods. In the period from May to the end of November 2021, in the Department of Pediatric Otolaryngology of the Pediatric Clinical Hospital of the Medical University of Warsaw, impedance audiometry was carried out on 319 children using Interacoustics Titan equipment. The results were analyzed for each patient and the age at which the patient was examined. Results. The most common type of tympanogram was type A (norm). The smallest number of results was obtained with the Ad type. We noted an increased number of pathology on the left side. Conclusions. Analysis of the results confirmed the important role of impedance audiometry in hearing tests. Extensive audiological diagnostics allow to minimize the risk of making mistakes, unnecessary hospitalizations, as well as unnecessary involvement of the operating theatre.
Children’s head and neck infections caused by Streptococcus intermedius in the Pediatric Otolaryngology Department of Warsaw Medical University
Authors: Jabłońska-Jesionowska Monika , Zawadzka-Głos Lidia
Published: February 2024

Introduction. Streptococci are commonly known pathogens of the normal bacterial flora of the mouth, pharynx, gastrointestinal tract and genitourinary system. The most common infections are beta-hemolyzing streptococci causing pharyngitis, streptococcal angina, otitis and paranasal sinusitis. But not all streptococcal infections are easy to treat. They are those that forming abscesses in the deep tissues of the body and caused life-treating complications. Aim. The aim of the study is to draw attention to the pathogen of the Streptococcus viridans group, i.e. Streptococcus intermedius, which, being a saprophyte of the upper respiratory tract, may cause life-threatening complications during an infection. Material and methods. The age, sex of children, underlying disease, complications, conservative and surgical treatment of children treated in the Pediatric Otolaryngology Department of the Medical University of Warsaw due Streptococcus intermedius infections were analyzed. Results. 6 children in age from 14 months to 15 years were treated in the ENT Department of Warsaw Medical University due to Streptococcus intermedius infections. There were 5 boys and 1 girl. All children were diagnosed with abscesses in deep tissue as a complication of acute sinusitis in 4 children, pharyngitis in 1 and post trauma nasal bone in 1 child. All children were immunocompetent. The treatment of choice was antibiotic therapy and drainage of abscesses. All children were successfully treated. Conclusions. The isolation of Streptococcus intermedius in cultures taken from infection’s site in the upper respiratory tract is associated with the risk of complications in the form of deep head and neck and central nervous system abscesses. Each patient with an infection of Streptococcus intermedius etiology requires CT or MRI imaging of the craniofacial and brain due to the possibility of deep abscesses. The treatment of choice is antibiotic therapy with ceftriaxone, clindamycin and together with surgical drainage of the abscess. The sensitivity of Streptococcus intermedius to popular antibiotics is the reason for effective treatment despite serious complications.
Tympanic membrane reconstruction of a persistent perforation associated with massive myringosclerosis in a girl with achondroplasia – case report
Authors: Wolniewicz Maria , Niemczyk-Cieślak Elżbieta , Zawadzka-Głos Lidia
Published: February 2024

Achondroplasia is a genetic disease connected with improper function of fibroblast growth factor receptor 3 (FGFR3) resulting in musculoskeletal disorders. Apart from characteristic musculoskeletal abnormalities (short statute with short proximal limb segments, prominent forehead, midface hypoplasia and a depressed nasal bridge) and generalized hypotonia it also affects otolaryngological field in a form of sleep-related upper respiratory tract disorders (obstructive and central apnea) and conductive hearing loss. This is the result of anatomical phenotype, together with Eustachian tube dysfunction. Interestingly, up to 25% of children with achondroplasia may fail hearing screening in one or both ears. In most cases laryngological disorders require surgical procedures, usually adenotomy, adenotonsillectomy, tonsillectomy or tube placement. Such surgical interventions increase the risk of complications, especially when repeated. We would like to present a case of a girl with achondroplasia that was qualified for myringoplasty because of persistent tympanic membrane perforation due to surgical extrusion of persistent ventilation tube, with associated massive myryngoslerosis.
Otosclerosis
Authors: Niemczyk-Cieślak Elżbieta , Zawadzka-Głos Lidia
Published: February 2024

Otosclerosis is a primary hereditary disorder of the otic capsule, affecting most commonly the area of the oval window. Stapes footplate fixation results in the immobility of the ossicular chain, which leads to progressive conductive hearing loss. Other symptoms include a sensorinerural component of hearing loss, tinnitus, and vestibular symptoms. Clinical otosclerosis occurs more frequently in women, and the first symptoms usually appear after childbirth in the 3rd decade of life. The etiology includes genetic, infectious, inflammatory, autoimmune, and hormonal factors. Audiological diagnostics for otosclerosis involves a battery of tests that complement one another, and the interrelation of their outcomes has a high predictive value. There are a few classifications of the disease, the majority of which are based on radiological criteria. Imaging studies mainly involve temporal bone high-resolution computed tomography, which has a relatively high sensitivity and specificity for detecting otosclerotic foci. Despite the availability of a wide variety of diagnostic techniques, the final diagnosis is still confirmed intraoperatively. Stapedotomy remains a reasonable primary intervention for the majority of patients with otosclerosis.
The use of electromyography in the diagnosis and treatment of anal sphincter dysfunctions
Authors: Namysł Jan , Garstka-Namysł Krystyna
Published: February 2024

Proper function of the anal sphincters largely depends on the integrity and efficiency of neural structures involved in controlling the maintaining stool and gas continence and compliant with the physiology and an individual’s will to empty the intestines. Nervous system disorders and injuries disrupt the bioelectrical activity of anal sphincters, the evaluation of which is important for both the treatment process and its outcomes. Electromyography, which is the only objective approach for assessing resting tone, the ability to maintain sphincter contraction and EMG biofeedback therapy, is the method of choice for assessing the bioelectrical activity of muscles. Electromyographic data significantly accelerate the diagnostic process and effective treatment implementation. If neurogenic aetiology of sphincter disorders is found, it is necessary to implement the rehabilitation process. The therapeutic approaches for neurogenic bowel dysfunction and stool or gas incontinence mainly include sphincter electrostimulation and/or biofeedback exercises, performed by patients at home, after training in the doctor’s office. The course of rehabilitation should be monitored as part of periodic follow-up EMGs.
Interventional treatment of haemorrhoids in anticoagulated patients
Authors: Kluciński Andrzej
Published: February 2024

Anticoagulants are currently widely used for cardiological reasons, stroke prevention and in other vascular diseases. Colorectal surgeons face patients suffering from haemorrhoids who are put on anticoagulant therapy in their everyday practice. Anticoagulation strategy for patients undergoing interventional treatment of haemorrhoids has not been discussed in detail in the literature so far. Standard management of grade 1-3 haemorrhoids includes rubber band ligation (RBL), sclerotherapy (SCL) and infrared coagulation (IRC) after unsuccessful conservative treatment. The rates of postprocedural bleeding range from 0.9-2.8% after rubber band ligation, 0-2.7% after sclerotherapy and 5% after infrared coagulation. Surgical procedures including dearterialization, haemorrhoidectomy and stapled haemorrhoidopexy are indicated in more advanced degrees as the third line of treatment and are complicated by postoperative bleeding in 1.4-5.9% and 2-7.9% patients, respectively. Haemorrhoidectomy is the best option in grade 4 haemorrhoids and is associated with 6.2-8.4% risk of bleeding. However, closed haemorrhoidectomy, Ligasure technique and/or anal tamponade can reduce this risk. Surgical guidelines recommend continuing acetylsalicylic acid in low bleeding risk procedures, including haemorrhoidal surgery. However, postoperative bleeding after rubber band ligation was more common in the aspirin group. On the other hand, haemorrhage incidence after sclerotherapy did not differ significantly between the group on anticoagulation compared with the group without anticoagulation. Haemorrhoidectomy should be postponed for 6 months in patients receiving dual antiplatelet therapy. According to the guidelines, vitamin K antagonists should be discontinued 5 days before haemorrhoidal surgery. Minimal bleeding risk procedures do not require discontinuation of anticoagulation,but this option seems to be hazardous for patients undertaking rubber band ligation. Sclerotherapy, on the other hand, could not require warfarin discontinuation if the international normalized ratio (INR) is within therapeutic range. Novel oral anticoagulants (NOACs) should be discontinued 1 day before low bleeding risk operations, including haemorrhoidectomy and resumed 1 day after the procedure. In conclusion, all anticoagulants should be ceased prior to operation except for aspirin. There are not clear recommendations on the perioperative protocols for continuation or discontinuation of blood thinners in patients undergoing minimally invasive procedures.
Treatment of hemorrhoidal disease in an atypical patient
Authors: Kołodziejczak Małgorzata
Published: February 2024

Therapeutic algorithms and recommendations for haemorrhoidal disease proposed in the literature are based on the stage of the disease. Less typical situations, such as reduced immunity in HIV infection, cancer patients on chemotherapy, chronic immunosuppressive treatment in patients after organ transplantation or patients with inflammatory bowel disease, as well as elderly patients with comorbidities that increase the risk of perioperative complications, are not usually discussed. On the other hand, publications on treatment complications in immunocompromised patients marginalise the problem of anorectal conditions, including common haemorrhoids. This paper presents the therapeutic management of haemorrhoidal disease in atypical patients. Furthermore, the specifics of the management of haemorrhoidal disease in a pregnant patient and in the perinatal period are also discussed.
Zastosowanie licówek o minimalnie inwazyjnej preparacji „no-prep” – praca poglądowa
Authors: de la Cerda Obraniak Maria , Cybulska Anna
Published: February 2024

Aesthetics is often the main reason for a patient to come to a dentist’s office. The desire to have a beautiful smile, with the awareness in society of the need to protect healthy tooth tissues, requires from the doctor to properly plan and carry out the treatment process. Modern dental prosthetics, should restore lost tissues, restore the function of the stomatognathic system and aesthetics, as well as follow the principles of minimal invasiveness of the procedures performed. The use of veneers in prosthetic rehabilitation allows an aesthetic reconstruction of lost, missing or discolored tooth tissues, reducing the risk of losing the tooth structure during preparation. Veneers with minimally invasive preparation i.e. no-prep are one of the possibilities of rehabilitation of patients, allowing for a satisfactory aesthetic effect with a slight reduction of tooth tissues. The use of these restorations is possible thanks to the progress made in the field of ceramics and the possibility of using thin veneers. Correct diagnostics, treatment planning, selection optimal material depending on clinical indications, precise laboratory and clinical stages of prosthetic restoration allow to achieve therapeutic success.
Comparison of micro-CT and CBCT in the preparation of teeth for the role of samples in in vitro research
Authors: Mazur Marek , Bolesta Kacper , Wieczorek Wiktoria , Portka Dominika , Olborska Maja , Regulski Piotr , Aluchna Marcin
Published: February 2024

Introduction. The thickness of dentine is an important factor affecting the results of experimental studies. An adequately precise and repeatable method for its measurement is of key importance for ensuring the reliability and credibility of research. Aim. The aim of this study was to compare conical beam computed tomography (CBCT) and microtomography (micro-CT) for the preparation of teeth as specimens in medical research. Material and methods. From among 100 extracted teeth, 4 teeth with appropriate structural features confirmed in CBCT images were selected. They were embedded in silicone mass and cut in a horizontal plane in such a way that the intersection plane was parallel to the plane defined by the pulp horns. Next, the samples were subjected to conical beam computed tomography and microtomography. Two authors independently measured the distance between the plane of intersection and the pulp horns on the obtained frontal and sagittal sections. The obtained measurements were statistically processed. Results. The values obtained with CBCT were higher than those obtained with micro-CT. Statistically significant differences were found for two of four samples. Conclusions. CBCT is not sufficient for precise preparation of teeth for the role of research specimens.
Teachers’ knowledge on caries aetiology and prevention – a pilot survey
Authors: Kobylińska Angelika , Gozdowski Dariusz , Olczak-Kowalczyk Dorota
Published: February 2024

Introduction. Education conducted by teachers, who should have up-to-date knowledge of the aetiology and prevention of caries, plays an important role in shaping dental health behaviours and attitudes in children. Aim. To assess the knowledge of primary school teachers on the aetiology and prevention of caries. Material and methods. Online surveys were conducted among primary school teachers in 10 voivodeships as part of the “Monitoring the oral health of the Polish population in 2016-2020” programme. The survey assessed the respondents’ knowledge of the aetiology of caries in children, as well as the benefits of dental care and caries prevention. Results. A total of 55 primary education teachers participated in the study. Most of the respondents pointed to bacteria (92.7%), sugar (96.4%) and their combination (98.2%) as aetiological factors of caries. Regular dental check-ups and tooth brushing were reported as preventive factors by all teachers. A total of 85.5% of respondents indicated the use of dental floss and only 74.5% knew the preventive effect of fluoride compounds. Participation in training courses on the prevention of oral diseases was declared by 23.6% of respondents, and 45.5% of teachers conducted classes on oral health among students in the past. Conclusions. The insufficient level of knowledge among Polish teachers about the aetiology and prevention of dental caries indicates the need for their substantive training so that they can conduct pro-health education for children. Studies in a larger group is needed to identify their educational needs.
Rzadka lokalizacja młodzieńczego beleczkowatego włókniaka kostniejącego – opis przypadku
Authors: Jaworska Edyta , Cyran Agata , Zawadzki Paweł J. , Sawicki Paweł , Poniewierski Wojciech
Published: February 2024

JTOF is a benign fibro-osseus lesion of aggressive clinical appearance, located mainly in maxilla and mandible, described in children between 8,5 and 12 years old. Trabecular (JTOF) and Psammomatoid (JPOF) Ossifying Fibromas are classified in the group of Fibro-osseous and osteochondromatous lesions according to WHO Classification (2017). Tumour does not affect the bone structure but due to its expansive growth may lead to facial asymmetry. In the described case, a 12-year-old boy was admitted to the dental office with a chief complaint of painless hard swelling of the hard palate which appeared about three weeks before and grew rapidly. Clinical examination revealed an asymptomatic, hard, well defined, pedunculated lesion connected to the tissues of marginal periodontium. Radiological examination did not reveal any pathologies. Surgical excision was performed, as the clinical appearance suggested fibrous epulis. Further histopathological examination with immunohistochemical staining revealed features of Trabecular JOF. No recurrence was observed in the follow up of three years. Described case of JTOF indicates that the lesion might be located extra-osseus in the soft tissues of the hard palate. JTOF should be taken into consideration in the differential diagnosis of pedunculated lesions of the mucosa among fibromatous epulis or peripheral ossifying fibroma (POF). Patients diagnosed with JTOF should be monitored both clinically and radiographically due to the high recurrence of the lesion.
Relationship between overweight/obesity and dental caries and oral hygiene among secondary-school students in Warsaw. Part I
Authors: Turska-Szybka Anna , Świątkowska-Bury Magdalena , Płusa Agata , Wawrzeńczyk-Gawałkiewicz Aleksandra , Gozdowski Dariusz , Olczak-Kowalczyk Dorota
Published: February 2024

Introduction. Both overweight/obesity and dental caries are referred to as civilisation diseases of the 21st century. Aim. The aim of the study was to assess the relationship between caries and oral hygiene and the occurrence of overweight and obesity in secondary-school students. Material and methods. A survey on health status, the most frequently consumed cariogenic products at school and the frequency of toothbrushing was conducted; BMI was calculated; as well as dental examination to assess caries (DMFT/DMFS) and oral hygiene (plaque index – PI) was performed among 141 randomly selected 18-year-old students of three secondary schools in Warsaw. Student’s t-tests, chi-square tests and Spearman’s correlation were used for statistical analysis (p < 0.05). Results. A total of 118 students were included in the study. The mean body weight was 59.53 ± 11.43 kg for women, and 78.57 ± 20.29 kg for men. There were 19 (16.1%) overweight and 3 (2.5%) obese adolescents. Higher BMI was found in men. The intake of cariogenic products was higher among students with a BMI < 25. About 83.3% of overweight and 66.7% of obese adolescents most often brush their teeth twice a day (differences not statistically significant). Caries was present in 112 (94.9%) students. The mean DMFT and DMFS were 6.52 ± 3.80 and 7.81 ± 5.66, and the plaque index was 0.75 ± 0.49. DMFT values were lower in subjects with BMI > 25, and PI was higher in overweight and obese participants (p > 0.05). Conclusions. There was no relationship between BMI and caries or hygiene indices, and no statistically significant differences between BMI and consuming cariogenic products. Individual prevention programmes and good cooperation with general practitioners can help improve the oral health and proper body weight in adolescents.
Cytotoksyczność i biokompatybilność kompozytowych, światłoutwardzalnych żywic stomatologicznych
Authors: Sułek Jolanta , Ossowska Anna , Marczuk-Kolada Grażyna , Hołownia Adam
Published: February 2024

The physical, chemical, and biological properties of restorative dental materials influence the clinical outcome of dental treatment. Methacrylate-based resins are extensively used in everyday dental practice, but accumulating records point to their toxicity. This article reviews the most important experimental data on cell-induced cytotoxicity of composite dental resins, methacrylates and epoxy compounds used to induce polymerization and reduce resin shrinkage. Methacrylate monomers produce reactive oxygen species, induce apoptosis and/or genotoxicity, and affect cell proliferation in culture. There is a need for awareness about the biological risks of these materials. New sensitive methods introduced to the preclinical testing of dental resins may help to highlight specific mechanisms, quantify the biological risk and guide the dentist to select the right biomaterial for dental applications.
PLANY MIGRACYJNE MŁODZIEŻY AKADEMICKIEJ KIELC
Authors: Kiniorska Iwona , Brambert Patryk , Staciwa Emilia
Published: February 2024

Celem badań było określenie preferencji migracyjnych kieleckich studentów, które wynikały z ich planów osobisto-zawodowych. W analizie wykorzystano dane jakościowe pochodzące z badań ankietowych zrealizowanych w 2023 r. Próbę badawczą stanowiło łącznie 200 studentów dwóch największych uczelni w mieście, tj. Uniwersytetu Jana Kochanowskiego w Kielcach oraz Politechniki Świętokrzyskiej. Rezultaty badań ankietowych stały się głównie podstawą do przeprowadzenia typologii przyczyn mobilności przestrzennej studentów za pomocą metody Warda. Wyznaczono dzięki niej cztery typy czynników determinujących migracje młodzieży akademickiej, z przewagą wektora ekonomicznego.
Oil/Brine Interfacial Phenomena and Their Application in Oil Spill Mitigation
Authors: Binabdi A. A. , Solling T. I. , El-Zohry A. M. , Ayirala S. , Gmira A. , Yousef A. A.
Published: February 2024

There is always a need to enhance and introduce methods or technology that can contain and clean up oil spills effectively. We propose a strategic approach and novel solution for oil spill mitigation focusing on the oil-water interface, which is the boundary between the seawater and oil spill phases. Therefore, we have studied the properties of the interface between oil and water to understand how interfacial phenomena occur when certain electrolytes are added to the brine phase and certain surfactants are added to the hydrocarbon phase. This was completed by utilizing an advanced force tensiometry device and traditional wet lab chemistry that are integrated to comprehensively analyze oil-water interface behavior over various brine solutions. A new method for cleaning up oil spills at sea involves creating a highly hydrophilic compound directly within the oil slick, which breaks up the oil and makes it easier to clean up.
Tratamento com corrente interferencial reduz a dor lombar e melhora a funcionalidade em pacientes com lombalgia crônica
Authors: Pereira Luiz Paulo Sobral , Silva Anderson Manoel Herculano da
Published: February 2024

Objetivo: Avaliar se o uso da corrente interferencial contribui para reduzir a dor lombar crônica e analisar se o protocolo eletroterapêutico pode beneficiar a funcionalidade física do paciente na lombalgia crônica. Métodos: Foram avaliados 24 indivíduos, com dor lombar acima de 12 semanas e com idade de 12 a 65 anos. A corrente utilizada na região lombar dos participantes foi do tipo interferencial tetrapolar e o modo de estimulação foi o vetor automático, com frequência portadora de 4.000 Hz, frequência de modulação (AMF) de 50 Hz e frequência de varredura de SWEEP de 20Hz. A avaliação da dor e da funcionalidade foram realizados utilizando como instrumento de coleta de dados a Escala Visual Analógica da dor (EVA), Rolland Morris Disability Questionnaire (RMDQ) e o Owestry Disability Questionnaire (ODQ), respectivamente. A análise dos dados foi realizada utilizando o software JAMOVI 2.2.5. Resultados: Os indivíduos submetidos a corrente interferencial apresentam melhora significativa na melhora da dor, bem como no padrão funcional. Conclusão: A corrente interferencial apresenta resultados simlilares nos grupos controles de eficácia comprovada, a técnica de aplicação produz resultados estatíticos no alívio da dor lombar crônica e na funcionalidade física de moderada a leve, nos indíviduos acometidos com os sintomas.
Desafios enfrentados pelo enfermeiro na aplicabilidade da lista de verificação de segurança cirúrgica (checklist)
Authors: Prates Mariana Machado , Dutra Joyce Moreira , Castro Maria de Fátima da Silva
Published: February 2024

Objetivo: Identificar as dificuldades enfrentadas pelo Enfermeiro junto à equipe na aplicabilidade do checklist no centro cirúrgico. Métodos: Trata-se de uma revisão integrativa. A busca dos artigos se deu em bases de dados, tais como: Literatura da América Latina e Caribe (LILACS), Biblioteca Eletrônica Científica Online (SCIELO) e Base de Dados de Enfermagem (BDENF). Resultados: A amostra f inal foi constituída por 7 publicações realizadas em centros cirúrgicos de todo o Brasil e que respondiam à pergunta norteadora. Após a análise dos artigos selecionados, foram elencadas duas categorias: 1-Não adesão e resistência por parte da equipe e 2-Falta de capacitação dos profissionais. Considerações finais: É necessário analisar os fatores que dificultam a aplicabilidade do checklist, bem como estabelecer as intervenções necessárias para diminuir essas dificuldades, a f im de se obter uma melhora na eficácia da aplicabilidade da Lista de Verificação de Segurança Cirúrgica (LVSC), para que, consequentemente, se tenha uma melhor prevenção dos eventos adversos e uma maior garantia da segurança do paciente.
Fatores predisponentes ao desenvolvimento da depressão pós-parto
Authors: Ferreira André Gomes , Vinhadelli Anna Luiza Zuconelli , Rocha Mariana da Silva , Santana Thalles Augusto Felex , Pereira Yamba Carla Lara
Published: February 2024

Objetivo: Descrever os fatores de riscos que são propensos a desenvolver Depressão Pós-parto (DPP) em puérperas. Métodos: Trata-se de uma revisão integrativa, feita a partir de trabalhos publicados de mulheres que desenvolveram depressão pós-parto. Os dados foram buscados nas plataformas Pubmed, Scielo, Acervo+ Index Base e também pelo buscador do Google acadêmico. Resultados: A amostra revelou que dentre os resultados obtidos, os fatores de risco para depressão pós-parto se dividem em quatro categorias predominantes, sendo elas: causas fisiológicas; causas sociais; causas psicológicas e causas comportamentais. Dentro dessas categorias, podemos destacar os fatores idade e escolaridade da puérpera, renda familiar, histórico psiquiátrico prévio e apoio familiar e/ou do genitor como os principais fatores de risco encontrados. Dessa forma, entende-se que a puérpera precisa de acompanhamento integral no período pós-parto. Considerações finais: Considera-se que os fatores como relação conjugal conflituosa, baixa renda, falta de rede de apoio, histórico de doenças psiquiátricas, nível de escolaridade estão atreladas ao desenvolvimento da depressão pós-parto nas mulheres brasileiras.
Os riscos do uso abusivo de benzodiazepínicos na população idosa
Authors: Ramos Gabriella Alves , Vasconcelos Lucia Helena Ferreira , Oliveira Danielle Furtado de , Duarte Nathalia Lopez
Published: February 2024

Objetivo: Analisar o risco do uso abusivo de benzodiazepínicos na população idosa. Revisão bibliográfica: Os determinantes comportamentais do risco de abuso e dependência de drogas do tipo benzodiazepínicos, com base na sua ação farmacológica, devem ser trazidos à luz da discussão entre os profissionais de saúde. O consumo por automedicação e por prescrição tem aumentado na população idosa, contribuindo para um maior número de quedas. Outros fatores importantes devem ser observados, como a presença de comorbidades - contexto no qual afecções como ansiedade e depressão alcançam índices mais elevados – pois, em paralelo, existem outras opções de tratamento farmacológico. Considerações finais: Torna-se importante o monitoramento dessa população que, além de fazer uso de outros fármacos para suas condições crônicas, ainda utilizam benzodiazepínicos de maneira não controlada, potencializando o risco de quedas e fraturas, bem como provocando a diminuição da atenção e aumentando a ocorrência de amnésia e instabilidade postural. Dessa forma, deve-se estimular e buscar a substituição, quando possivel, de benzodiazepínicos por terapias alternativas, farmacológicas ou não.
Anemia megaloblástica induzida por fármacos
Authors: Vieira Gabriela , Vasconcelos Lucia Helena Ferreira , Oliveira Danielle Furtado de , Duarte Nathalia Lopez
Published: February 2024

Objetivo: Realizar uma análise sobre anemia megaloblástica induzida por fármacos, discorrendo sobre medicações frequentemente utilizadas na prática clínica. Revisão bibliográfica: A anemia megaloblástica é um tipo de anemia caracterizada por anormalidades morfológicas dos núcleos dos precursores eritroides, os quais tendem a ser grandes e imaturos. As causas mais comuns são deficiências de vitamina B12 ou folato. O uso de certos medicamentos com outras finalidades terapêuticas que intervêm na absorção desses nutrientes pode levar à anemia megaloblástica induzida por fármacos.  Pode ocorrer em pessoas de todas as idades, sendo mais comum em idosos e em indivíduos com doenças crônicas. Os sintomas da anemia megaloblástica induzida por fármacos são semelhantes aos de outros tipos de anemia. Considerações finais: Durante a avaliação de um indivíduo com diagnóstico de anemia megaloblástica, deve-se considerar o seu contexto nutricional, níveis séricos de micronutrientes, macromoléculas e metabólitos como vitamina B12, ferritina, ferro, acido metilmalônico e homocisteína, bem como realizar uma minuciosa avaliação clínica e atentar aos medicamentos em uso pelo paciente, os quais devem ser avaliados quanto à possibilidade de estarem induzindo a anemia megaloblástica.
Examining the Involvement Level of People who Practise Karate
Authors: BOZKURT Alper , TÜRKERİ Cenab
Published: February 2024

This study aims to determine the participants’ level of involvement who are engaged in karate in Adana and whether this involvement differs according to the demographic variables of the people. The data were collected from karate clubs in Adana via a survey. Analyses were carried out on 268 valid surveys. According to the analysis results, the participants' involvement in karate shows significant differences according to marital status, age, how many years karate has been practised, how often karate is practised and going out of province for karate purposes. Besides, while the dimension with the highest mean of the scale of involvement in karate sport is "Attraction" (x̄=4,54), the dimension with the lowest average is "Identity Expression" (x̄=3.57). Lastly, the general average of the scale items is x̄=4,01. Based on this, it can be interpreted that the participants' interest in karate is generally high. These results highlight the positive tendencies of individuals involved in karate and underline the attractiveness and importance of the activity in their lives.
Electron-Transferring Metalloenzymes and their Potential Biotechnological Applications
Authors: Milton Ross D.
Published: February 2024

Modern societies rely heavily on centralized industrial processes to generate a multitude of products ranging from electrical energy to synthetic chemical building blocks to construction materials. To date, these processes have relied extensively on energy produced from fossil fuels, which has led to dramatically increased quantities of greenhouse gases (including carbon dioxide) being released into the atmosphere; the effects of the ensuing change to our climate are easily observed in day-to-day life. Some of the reactions catalyzed by these industrial processes can be catalyzed in nature by metal-containing enzymes (metalloenzymes) that have evolved over the course of up to 3.8 billion years to do so under mild physiological conditions using Earth-abundant metals. While such metalloenzymes could in principle facilitate the implementation of carbon-neutral processes around the globe, either in “bio-inspired” catalyst design or even by direct exploitation, many remaining questions surrounding their mechanisms often preclude both options. Here, our recent efforts in understanding and applying metalloenzymes that catalyze reactions such as dinitrogen reduction to ammonia or proton reduction to molecular hydrogen are discussed. In closing, an opinion on the question: “Can these types of enzymes really be used in new biotechnologies?” is offered.
Practical Approaches to Genetic Code Expansion with Aminoacyl-tRNA Synthetase/tRNA Pairs
Authors: Natter Perdiguero Anton , Deliz Liang Alexandria
Published: February 2024

Genetic code expansion (GCE) can enable the site-selective incorporation of non-canonical amino acids (ncAAs) into proteins. GCE has advanced tremendously in the last decade and can be used to create biorthogonal handles, monitor and control proteins inside cells, study post-translational modifications, and engineer new protein functions. Since establishing our laboratory, our research has focused on applications of GCE in protein and enzyme engineering using aminoacyl-tRNA synthetase/tRNA (aaRS/tRNA) pairs. This topic has been reviewed extensively, leaving little doubt that GCE is a powerful tool for engineering proteins and enzymes. Therefore, for this young faculty issue, we wanted to provide a more technical look into the methods we use and the challenges we think about in our laboratory. Since starting the laboratory, we have successfully engineered over a dozen novel aaRS/tRNA pairs tailored for various GCE applications. However, we acknowledge that the field can pose challenges even for experts. Thus, herein, we provide a review of methodologies in ncAA incorporation with some practical commentary and a focus on challenges, emerging solutions, and exciting developments.
Rotational-state-selected Carbon Astrochemistry
Authors: Toscano Jutta
Published: February 2024

The addition of individual quanta of rotational excitation to a molecule has been shown to markedly change its reactivity by significantly modifying the intermolecular interactions. So far, it has only been possible to observe these rotational effects in a very limited number of systems due to lack of rotational selectivity in chemical reaction experiments. The recent development of rotationally controlled molecular beams now makes such investigations possible for a wide range of systems. This is particularly crucial in order to understand the chemistry occurring in the interstellar medium, such as exploring the formation of carbon-based astrochemical molecules and the emergence of molecular complexity in interstellar space from the reaction of small atomic and molecular fragments.
Interfacial Chemistry and Catalysis of Inorganic Materials
Authors: Chang Chien Tzu-Chin , Delley Murielle F.
Published: February 2024

Heterogeneous catalysis is essential to most industrial chemical processes. To achieve a better sustainability of these processes we need highly efficient and highly selective catalysts that are based on earth-abundant materials rather than the more conventional noble metals. Here, we discuss the potential of inorganic materials as catalysts for chemical transformations focusing in particular on the promising transition metal phosphides and sulfides. We describe our recent and current efforts to understand the interfacial chemistry of these materials that governs catalysis, and to tune catalytic reactivity by controlled chemical modification of the material surfaces and by use of interfacial electric fields.
МЕТОДИЧЕСКИЕ АСПЕКТЫ ОРГАНИЗАЦИИ ДИСКУССИЙ СТУДЕНТОВ ПО МЕТОДУ ХАКНЕССА
Authors: Алимова Ф.А.
Published: February 2024

В данной статье рассматривается методика проведения дискуссий по методу Хакнесса. Показаны методические и организационные условия подготовки студентов педагогических вузов строить учебную дискуссию, ориентированную на развитие творческого мышления, дающую возможность самим принимать решения, анализировать возникающие у них различные идеи и подходы, строить действия в соответствии со своими решениями.
ТОРГОВЛЯ ЗОЛОТОЙ ОРДЫ НА УРАЛЕ
Authors: Сагидуллаев Д.З.
Published: February 2024

Торговля в Улусе Джучи, сложившаяся в XIII веке, и его развитие, место Улуса Джучи в мировой торговле того времени сегодня привлекает внимание многих исследователей. Основная цель нашей статьи - рассмотреть систему торговли в Улусе Джучи, определить караванные пути, соединявшие Нижнюю Волгу и Среднюю Азию через р. Урал. Написание статьи осуществлялось методом анализа и сопоставления данных о торговле в Золотой Орде. В результате исследования рассматривались торговые пути вдоль р. Урала в направлении Сарайчик, Хорезм, Отрар, сложившиеся в Улусе Джучи.
ТРУДНОСТИ ПЕРЕДАЧИ МЕТАФОР С НЕМЕЦКОГО ЯЗЫКА НА РУССКИЙ ПРИ ПЕРЕВОДЕ ТЕКСТОВ ПРОИЗВЕДЕНИЙ СТЕФАНА ЦВЕЙГА И СПОСОБЫ ИХ ПРЕОДОЛЕНИЯ
Authors: Терехова Е.В. , Микалюк П.В.
Published: February 2024

Статья посвящена подробному исследованию трудностей перевода метафор и способов их преодоления на основе произведений С. Цвейга. В статье выделяются и анализируются трудности, возникающие перед переводчиками новелл С. Цвейга в процессе передачи метафор на русский язык, а также исследуются переводческие приемы и трансформации, позволяющие их преодолеть. Особый интерес представляет выделение трудностей передачи метафор, которые связаны с идиостилем писателя.
المعالجة الإخبارية لقضية الإرهاب في القنوات الفضائية دراسة وصفية تطبيقية على قناة الجزيرة القطرية في الفترة من مايو 2018م- مايو 2019م
Authors: جادين نجلاء حمدان
Published: February 2024

تعالج الدراسة المعالجة الإخبارية لقضية الإرهاب في القنوات الفضائية ، ويتناول البحث قضية الإرهاب كمادة إعلامية ذات قيمة إخبارية تتناولها وسائل الإعلام وتطرح إشكالية كبيرة في الكيفية والطريقة التي ينبغي أن تعالج بها، وتم إختيار قناة الجزيرة القطرية لأنها كانت من أولى الفضائيات العربية الإخبارية المتخصصة في ،وإتخذت منهجا جريئا بطرح كل الأحداث وإهتمت بالرأي والرأي الأخر ومننهج الدراسة هو المنهج الوصفي التحليلي بأختيار عينة عشوائية منتظمة للنشرات الإخبارية الرئيسية للقناتين لمدة عام، وخلصت الدراسة لعدة نتائج أهمها :- الاهتمام الكبير بقضية الإرهاب من قبل قناة الجزيرة القطرية ، التغطية الإخبارية لقضية الإرهاب كانت في اغلبها إيجابية كما إستخدمت القناة كل الوسائل التقنية والإيضاحية في عرضها لقضية الإرهاب وأوصت الدراسة قناة الجزيرة بالإبتعاد عن الأسلوب التكراري الدعائي في طرح القضية وترديد المصطلح حتى لاتكون خدمت الإرهابيين بصورة غير مباشرة وأيضا عدم ربط الإرهاب بالأسلام من خلال عرض الشعارات والأسماء التي تطلقها الجماعات الإرهابية حتى لا تسيئ للإسلام.
UJI MULTIKOLINEARITAS: PENGARUH PEMBANGUNAN INFRASTRUKTUR TERHADAP PENGURANGAN TINGKAT PENGANGGURAN DI KAB. SIDOARJO
Authors: Rahma Dilla Nur , Kumala Dewi Refita Ayu , Widya nanda Angelika Gladys
Published: February 2024

Economic growth is an indicator of the success of economic development, characterized by the process of increasing output per capita in the long term. Efforts to accelerate regional development can be done by increasing economic growth. Efficiency in economic activities must be accompanied by adequate infrastructure, especially road and electricity infrastructure, so that it will encourage a sustainable increase in regional potential, where the development of infrastructure in Indonesia is currently progressing quite rapidly in Indonesia, both in national and regional infrastructure development. One of the areas that is developing rapidly in the infrastructure development process is Kab. Sidoarjo. District growth. Sidoarjo from 2010 to 2020 has not yet met the target in terms of development, there is still a lot of infrastructure that has not been improved, however, in the development of infrastructure development which will start in 2021, there will be a lot of development in infrastructure starting in the District. Sidoarjo, starting from road concreting to fulfilling public facilities carried out by the District Public Works and Spatial Planning Department. Sidoarjo. In infrastructure development in Kab. Sidoarjo can have a significant influence on economic growth which is used in economic growth and in infrastructure development, of course absorbing local energy which is used to fulfill work requirements in the district. Sidoarjo.
PEMENUHAN INVESTASI DAERAH DAN TINGKAT PENDIDIKAN TERHADAP PERTUMBUHAN EKONOMI
Authors: Imammudin Yusuf , Satriatama Keifan Galuh , Anjaska Reza
Published: February 2024

This research aims to analyze the influence of investment in an area with a level of education on economic growth in the vulnerable city of Bandar Lampung from 2019 to 2023. According to data collected at BPS Lampung Province 2023, the economic growth of the city of Bandar Lampung from 2019 to 2023 is moving fluctuatingly, which in this case is influenced by several factors, including investment in the workforce and the level of education in the city of Bandar Lampung. The data used in this research uses vulnerable secondary data from 2019 to 2023 using documentation methods obtained from the BPS of Bandar Lampung City province. By using multiple linear regression analysis. The results of research referring to investment fulfillment based on linear regression test results show results on investment variables (0.023<0.05) along with education level (0.001<0.05) which have a positive effect on the economic growth of the city of Bandar Lampung. And based on the simultaneous level of Bandar Lampung City at 99.8%, which refers to the welfare index that comes from fulfilling investment and education levels in Bandar Lampung City.
CHARACTERISTICS OF TRAFFIC ACCIDENTS ON 4/2D ROAD TYPES ON THE SURABAYA - MOJOKERTO TOLL ROAD ( CASE STUDY: WARUGUNG - PENOMPO TOLL ROAD SECTION)
Authors: Laksono Achmad Ipung Dwi , Moetriono Hary
Published: February 2024

In developing road infrastructure, keeping pace with the transportation sector and the rapidly growing economy is vital. Inadequate road infrastructure conditions will cause problems on the road, namely traffic accidents and congestion, which results in a lack of driver comfort. PT Jasa Marga can undoubtedly find out the leading cause of the accident. This study aimed to determine the characteristics of traffic accidents on the 4/2d road type, precisely on the Surabaya - Mojokerto toll road on the Warugunung - Penompo toll road. The Surabaya–Mojokerto Toll Road or Sumo Toll Road is a 36.27-kilometer-long toll road that connects the City of Surabaya with the City of Mojokerto, East Java Province. This toll road is connected to the Kertosono-Mojokerto Toll Road to the west. The class of vehicles on this toll road, such as trucks and large-laden cars, can also be said to be one of the characteristics of traffic accidents. Location of accident-prone points (BlackSpot) on the Warugunung – Penompo toll road in 2021 on line A, namely at Km 3+000 – 4+000 of the Warugunung – Driyorejo section, because at that location there are road slopes and bends, so many motorists drive at high speed high and have to slow down when there is a descent and many riders do not anticipate it. In 2021, line B, namely at Km 5+000 - 6+000 on the Warugunung - penompo section, is not much different from line A.
Recurrent Massive Gastrointestinal Bleeding as a first presentation of AL Amyloidosis in a 76-Year-Old Patient
Authors:   Internal medicine A ward, Meir Medical Center, Kfar Saba Israel, Rabina Eilam , Tal Sagee ,   Pathology Institute, Meir Medical Center, Kfar Saba Israel, Rudnicki Yaron ,   General surgery B ward, Meir Medical Center, Kfar Saba Israel, Rahmani Assaf ,   General surgery B ward, Meir Medical Center, Kfar Saba Israel, Naftali Timna ,   Tel Aviv University, Israel, Ellis Martin H ,   Tel Aviv University, Israel, Dolberg Osnat Jarchowsky ,   Internal medicine A ward, Meir Medical Center, Kfar Saba Israel
Published: February 2024

Background: Light chain or AL amyloidosis is a systemic disease that occasionally involves the gastrointestinal tract, but very rarely presents as gastrointestinal bleeding without evidence of systemic involvement. In such cases recognition of amyloidosis as the cause of bleeding is essential in order to rapidly initiate effective treatment to stop the bleeding. Case presentation: We describe a 76-year-old patient who presented with recurrent massive gastrointestinal bleeding as the initial manifestation of AL amyloidosis. One episode necessitated emergency right colectomy, and histopathological analysis of the resected bowel revealed diffuse amyloid infiltration. This finding prompted further investigations, which demonstrated elevated plasma lambda light chain levels, and 10% monoclonal plasma cells in the bone marrow. Treatment with bortezomib, dexamethasone, and daratumumab was initiated and no further gastrointestinal bleeding occurred. Conclusion: The diagnosis of amyloidosis involving the gastrointestinal tract should be considered in adult patients with unexplained recurrent gastrointestinal bleeding.