bluuebunny/crossref_metadata_2025 huggingface dataset:
Перспективы применения иммуномодулирующих препаратов и модуляторов цереблон Е3-лигазы в лечении множественной миеломы
Authors: Семочкин Сергей Вячеславович
Published: October 2023

In recent decades, the progress in multiple myeloma (MM) treatment has been linked to a clearer insight into the biology of this disease and practical application of new pharmaceutical classes, such as immunomodulatory drugs (IMiDs), proteasome inhibitors (PIs), and monoclonal antibodies (MABs). Modern IMiDs (lenalidomide and pomalidomide) are thalidomide derivatives which despite the similarity of chemical structure show only a relative cross-resistance. Lenalidomide is a second-generation immunomodulator with high anti-tumor activity and a favorable safety profile. In 2006, the use of lenalidomide combined with dexamethasone (Rd regimen) was approved by FDA (USA) for the treatment of relapsed/refractory MM, and 9 years later, in 2015, for newly diagnosed MM. During 2015–2019, the treatment of relapsed MM applied the newly developed regimens involving Rd combined with bortezomib (VRd), carfilzomib (KRd), ixazomib (IRd), elotuzumab (ERd), and daratumumab (DRd), the so-called triplets. Pomalidomide is a third-generation drug used in lenalidomide-refractory patients. For patients with relapsed/refractory MM who received at least two therapy lines with lenalidomide and bortezomib, regimens with 3 drugs were introduced which include pomalidomide and dexamethasone combined with elotuzumab (EPd), isatuximab (Isa-Pd), and daratumumab (DPd). In 2010, the molecular target of IMiD action was discovered, that is protein cereblon (CRBN), a component of CRBN E3 ligase enzyme complex. The insight into this mechanism provided the basis for developing a new family of thalidomide derivatives which are now called CRBN E3 ligase modulators (CELMoDs). In phase I/II trials, two drugs belonging to this group (iberdomide and mezigdomide) showed promising activity in MM refractory to three classes of antitumor drugs (IMiDs, PIs, and anti-CD38 MABs). The present review is focused on prospective studies of IMiDs and CELMoDs at different stages of MM treatment.
Vibration characteristics and seismic performance of historical buildings with brick-wood structures
Authors: Li Liang , Liu Ping , Fu Jianhua , Yang Jianjiang
Published: October 2023

To explore the vibration characteristics and seismic performance of historical buildings in Tianjin, we conducted on-site vibration testing under ambient vibration on three historical buildings with brick-wood structures in Tianjin. Specifically, we delved into the vibration characteristics and seismic performance of historic buildings with brick-wood structures by establishing the vibration analysis model, performing the theoretical calculations, and conducting seismic performance analysis. The results reveal that 1) the vibration frequencies of historical buildings with brick-wood structures are low, mainly concentrated in 2.0-8.0 Hz, which conforms to the vibration range of general buildings; 2) based on vibration analysis, it is concluded that the structural integrity of these buildings is good and there are no obvious structural defects; 3) the layout and storey height of historical buildings have great impacts on the vibration characteristics and seismic performance. 4) the comprehensive seismic capacity index of three buildings ranges from 0.91 to 1.75. The results of dynamic analysis under ambient vibration are consistent with those of theoretical analysis, providing a basis for preserving and reinforcing historical buildings.
Strengthening of Soviet Power in the Voronezh Province in the Second Half of 1918
Authors: Zayats N. A.
Published: October 2023

The relevance of this article is determined by the fact that the creation of a system of authorities in Soviet Russia is one of the popular topics of Soviet and modern historiography. However, this issue is being studied in the main national context of the evolution of the Soviet state. Meanwhile, this topic requires research on regional material, showing both general patterns on a national scale of this process, and local specifics.

The purpose of the article is to study the formation of the Soviets of the Voronezh province in the second half of 1918 and the development of their organizational structure by the Bolsheviks.

Objectives: to determine the activities of the Bolsheviks in the development of the system of Soviet power, the effectiveness of this work and the local features of this process.

Methodology. The research is based on the principles of objectivity and historicism. To solve the tasks set, methods were used: historical-genetic and historical-systemic.

The results of the scientific research made it possible to draw certain conclusions related to the organization of the Soviets in the second half of 1918.

Conclusions. Only in the second half of 1918 did the development of the work of local Soviets begin, which took place mainly thanks to the help of the provincial center. In the countryside, this process was even more difficult, since the Bolsheviks had almost no class support there. To receive it, party cells and committees of the poor were formed, which by the end of 1918 began to reorganize the village councils to form their composition loyal to the authorities. During this period, the Soviet authorities suffered from weak support from the population, lack of personnel and finances, instructions and work experience, and disloyal composition in the countryside. However, but by the end of 1918 they managed to satisfactorily organize their work, consolidate their power in Voronezh and county centers, and begin large-scale work to create loyal Soviets in the countryside.
Public Law of Moldova in the 16th – 17th Centuries
Authors: Pogorleckaya I. I.
Published: October 2023

Relevance. The public legal relations of Moldova in the 16th-17th centuries continue to develop against the backdrop of legislative processes and the adoption of the Code of 1646 - the first monument of Moldovan law. The adoption of the Code marked a new stage in the development of public law in general, the areas of legal proceedings and criminal law in particular. Despite the fact that the Code of 1646 contained norms and institutions that were progressive for their time, it consolidated the tendency to toughen criminal liability for crimes against the backdrop of an intensified class struggle in Moldovan society.

The purpose of the article is to determine the range of the main sources of public law in Moldova in the 16th - 17th centuries, as well as the features of the development of public law branches and their individual institutions in medieval Moldova.

Objectives: analyze the main sources of public law in Moldova in the 16th-17th centuries; to determine the features of public law institutions of the medieval Moldavian state.

Methodology. The methodological basis was the historical method of research. Along with the historical method of research, the principles of consistency and scientific objectivity were used.

The results of the scientific study showed that the period under study is represented by many heterogeneous sources of public law, a special place among which is occupied by the first monument of the law of Moldova - the Code of Vasily Lupu of 1646, containing, for the most part, norms of a criminal law nature. Despite the fact that the Moldavian medieval law was characterized by a pronounced class character, it not only reflected the class character of social relations, but also contained norms and provisions progressive for its time.

Conclusions. In general, we can conclude that during the XVI-XVII centuries the area of public law relations continues to develop. This was facilitated by the adoption of the Code of 1646, which, in essence, acted as a monument of criminal law. Along with the Code, other monuments of law continue to be applied, including both Byzantine legislation and canonical collections. Moldavian feudal law, like the law of other European states, was characterized by a class character. At the same time, the first monument of Moldovan law - the Code of Vasily Lupu of 1646 - contained a developed conceptual apparatus, progressive concepts for its time, such as recidivism, necessary defense, extreme necessity, mitigating and aggravating circumstances, circumstances excluding criminal liability.
Copyright Compliance with Non-contractual Transfer of Exclusive Rights to Works
Authors: Kozlova M. V.
Published: October 2023

Relevance. The author researches legislative provisions, judicial practice and scientific publications on the issues of transfer of exclusive rights to works to third parties without a contract. The legislation establishes various grounds for such a transfer (reorganization of a legal entity, inheritance, foreclosure on the property of the right holder), but not in all of these cases the rights and legitimate interests of authors and their heirs are fully taken into account. The article substantiates additional measures aimed at taking into account the interests of the author as a "weak party" of the arising legal relations.

The purpose of the study is to determine measures aimed at balancing the interests of participants in civil legal relations while respecting the rights of authors of the results of creative activity.

Objectives: to determine the peculiarities of the non-contractual transfer of exclusive rights to other persons, including the inheritance of copyrights, foreclosure of exclusive rights to works and reorganization of legal entities; identify contradictions between the interests of authors and other persons in the non-contractual transfer of exclusive rights to works.

Methodology. The dialectical-materialistic method, systematic method, methods of analysis and synthesis, formal-legal method were used in preparing the work.

The results of the research are of theoretical and applied nature and are aimed at improving the quality of legal regulation of unusual aspects of civil legal relations.

 Conclusions. The conclusions made in the article are of a discussion nature, aimed at the continuation of research in the framework of the stated topic. In case of non-contractual transfer of the exclusive right to other persons contradictions between the interests of authors, their heirs, other right holders, creditors, reorganized legal entities and other individuals and legal entities are manifested. The principle of priority observance of the author's rights should be applied in all cases, but the search for legislative solutions and development of judicial practice should also take into account the need to achieve a reasonable balance of interests of all participants of civil legal relations.
A meta-analysis of randomized sham-controlled trials of repetitive transcranial magnetic stimulation for attention-deficit/hyperactivity disorder (Preprint)
Authors: Hung Kuo-Chuan , Cheng Ching-Ming , Liang Shun-Chin , Sun Cheuk-Kwan , Chen Chia-Min , Cheng Yu-Shian , Chiu Hsien‐Jane
Published: October 2023

BACKGROUND

Efficacy of repetitive transcranial magnetic stimulation (rTMS) against attention-deficit/hyperactivity disorder (ADHD) remains unclear.

OBJECTIVE

To investigate the treatment efficacy of rTMS against the symptoms of ADHD as well as identifying the potential factors that may affect the therapeutic efficacy of rTMS through subgroup analysis.

METHODS

Randomized sham-controlled trials (RCTs) were identified from major databases from inception to January 2022. Primary outcome was improvement in total symptoms of ADHD. Subgroup analysis focused on rTMS efficacy targeting different brain regions. Secondary outcomes were associations of rTMS with improvements in different symptoms. Outcomes were expressed as effect size (ES) based on standardized mean difference (SMD) (continuous data), and odds ratios (ORs) with 95% confidence interval (CI) (categorical data).

RESULTS

Meta-analysis of six RCTs involving 169 participants demonstrated no difference in total ADHD symptoms between rTMS-treated participants and sham controls (SMD=-0.24, p=0.17). Subgroup analysis revealed better efficacy of rTMS than sham controls when targeting rPFC (SMD=-0.49, p=0.03), but not lPFC (SMD= 0.01, p=0.67). rTMS treatment correlated with better improvement in symptoms of inattention (SMD=-0.76, p=0.0002), but not hyperactivity (p=0.86), impulsivity (p=0.41), and depression (p=0.95). The apparently higher risk of dropout in the rTMS group than sham controls was not statistically significant (OR=1.65, p=0.26).

CONCLUSIONS

Our study only supported the therapeutic efficacy of rTMS targeting rPFC for the symptoms of ADHD, especially inattention, but not that targeting lPFC. Further large-scale randomized sham-controlled trials are required to verify our findings.

CLINICALTRIAL

PROSPERO CRD42023393713
Factors that Affect the Adoption of Mobile Banking in Case Commercial Bank of Ethiopia, Gambella People’s National Regional State Branch, Gambella, Ethiopia
Authors: Ruey Chuol Jock , Thot Nhial Biel
Published: October 2023

The primary aim of this study was to examine factors influencing consumers’ adoption of mobile banking services Gambella region, Ethiopia. From the literature, seven determinant factors were identified. Each variable were measured by using yes or no questions. This study combines TAM and IDT along with perceived risk, awareness constructs and perceive trust. The primary data were collected using questionnaires distributed to customers of Commercial bank of Ethiopia for mobile banking users. The Statistical Package for Social Sciences (SPSS) version 20 was used to analyze the data. Descriptive and inferential statistics were used to address the research objectives and binary logistic regression analysis employed. The results revealed that, with exception of perceived risk, perceived usefulness, perceive ease of use; perceive trust, performance expectancy and awareness have positive and statistically significant with the adoption of mobile banking. This study recommended that, banks should encourage and create awareness to the public through emphasizing the benefits or advantages that can be gained from the mobile banking services to increase the adoption level and to provide further directions into mobile banking strategies for mobile network operators, banks and service provider to design and implement mobile banking services to yield higher consumer acceptance.
Nonlinear Influence of Digital Economy on Rural Revitalization
Authors: Wang Jiatong
Published: October 2023

By measuring the level of digital economy and rural revitalization in different regions, this paper analyzes the nonlinear impact of digital economy on rural revitalization by using a panel threshold regression model. It is found that when the consumption level of rural residents and digital inclusive finance level are taken as threshold variables, the impact of digital economy on rural revitalization has single and double threshold effects respectively. With the improvement of rural residents’ consumption and digital inclusive finance levels, the digital economy plays an increasingly important role in promoting rural revitalization, showing a rising trend. Further, through grouping regression, it is found that the promotion of digital economy to rural revitalization is only significant in the western region where the economy is relatively backward, but not significant in the central and eastern regions.
Exploring Female Empowerment: A Comparative Study of Jane Austen’s Pride and Prejudice and Charlotte Brontë’s Jane Eyre
Authors: Mohammed Najlaa Hosny Ameen
Published: October 2023

This research paper explores female empowerment in literature via a comparative analysis of Jane Austen’s Pride and Prejudice and Charlotte Brontë’s Jane Eyre. The paper examines the main female characters in each novel, their portrayal of agency, independence, and autonomy, and the social and cultural factors that shape their experiences. Through this analysis, the paper identifies the similarities and differences in the approaches taken by Austen and Brontë, and discusses the implications of these findings for our understanding of female empowerment in literature and society. The paper argues that both novels offer powerful critiques of patriarchal society and highlight the need for collective action and solidarity among women, in order to achieve true empowerment. The research contributes to our understanding of gender and empowerment in literature, and provides insights into the on-going struggle for gender equality.
The Sun Rises in the West: A Review Essay on Ismailism
Authors: Mohomed Carimo
Published: October 2023

This review essay uses three books to explore some aspects of Ismailism. The books are THE FATIMIDS 2. THE RULE FROM EGYPT, by Shainool Jiwa. London/New York: I. B. Tauris / The Institute of Ismaili Studies, 2023, pp. VIII + 240. ISBN: 9781780769486; COMMAND AND CREATION. A SHI‘I COSMOLOGICAL TREATISE. A Persian edition and English translation of Muḥammad al-Shahrastānī’s Majlis-i maktūb. Edited and Translated by Daryoush Mohammad Poor. London/New York: I. B. Tauris / The Institute of Ismaili Studies (Ismaili Texts and Translation Series, 25), 2021, pp. XVI + 138 + LXXXIV. ISBN: 9780755602971; and FAITH AND ETHICS: THE VISION OF THE ISMAILI IMAMAT, by M. Ali Lakhani. London/New York: I. B. Tauris / The Institute of Ismaili Studies, 2018, pp. 1 colour illustration + XXIV + 248. ISBN: 9781788312486.
Plant extracts as potential for Anti-feeding activity of rodents and some important insects pest: An eco-friendly approach for pest control.
Authors:   Department of Zoology, Acharya Prafulla Chandra College, New Barrackpur, West Bengal, India, Madhu Nithar Ranjan , Sarkar Bhanumati ,   Department of Botany, Acharya Prafulla Chandra College, New Barrackpur, West Bengal, India, Biswas Paramita ,   Assistant Professor, Department of Agronomy, Faculty of Agriculture, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar – 736 165, West Bengal, India, Patra Ashis ,   Department of Life Science, Barda Gangadhar High School, Barda, West Bengal, India, Biswas Surjyo Jyoti ,   Department of Zoology, Midnapore College, Midnapore, West Bengal, India, Behera Biplab Kumar ,   Department of Zoology, Siliguri College, West Bengal, India
Published: October 2023

The present study was conducted to investigate the effect of leaf extract of neem (Azadirachta indica) and bel (Aegle marmelos) mixed with cow urine (neem + bel): cow urine: 9:2 ratio] that confirm protection against all types of rats and many agricultural pests and diseases on agricultural field of rice (Oryza sativa), pumpkin (Cucarbita maxima) and cauliflower (Brassica oleraceavar. botrytis). 400 gm of neem leaves and 200 gm of bel leaves are cooked in a container for 20 minutes with 10 litre of tap/pond water. The container was filtered and kept at room temperature. Now 2 litres of cow urine was mixed with the extract and sprayed during evening hours for three or four times at monthly intervals. This extracts exerted strong anti-feedant activity to the rats and insects. The use of pesticides are regarded as ecologically non-degradable, unacceptable in the study area. Therefore, this study is an eco-friendly approach for pest control which are effective, biodegradable and do not have harmful effect of its own environment. Keywords: Aegle marmelos, antifeedant activity, Azadirachta indica, eco-friendly approach, Plant extract
Interaction of plant extracts and spinosad as strong insecticidefor integrated pest management programs
Authors:   Department of Zoology, Acharya Prafulla Chandra College, New Barrackpore, West Bengal, India, Madhu Nithar Ranjan
Published: October 2023

A major research interest with spinosad and anti-feedants, especially seeds and leaf extract of neem & bel mixed with cow urine [(neem + bel): cow urine: 9:2 ratios] have been used for the control of a variety of insect pests. Most of the experiments, pests have effected on their life cycle and significance results were screening from the field survey. It is also observed that these experiments do not effect of its food production. But application of cow dung and neem cake use as good fertilizer which provide defence to plants against pests and deal with toxicity to both insect pests. Application of cow dung and neem cake is also help to reduce soil pest and nematodes. Spinosad based on bio-pesticide appears to be effective by ingestion and contact and causes excitation of the insect nervous system, leading to involuntary muscle contractions, prostration with tremors and finally paralysis. Broadcasted plants extract are also prevented from insect damages of young and adults plants. Therefore, spinosad, seeds and leaf extract of neem and bel mixed with cow urine based products are more suitable biodegradable, eco-friendly bio-pesticides for integrated pest management programs and can be used upon the peak of insect populations density. Keywords: Aegle marmelos, Azadirachta indica, eco-friendly, spinosad
Investigate the Concept of SNAYU from Shushrut Samhita
Authors: Choudhary Dr. Pallavi , Mahich Dr. Mukesh Kumar , Kumari Dr. Krishna , Sharma Dr. Mahendra Kumar
Published: October 2023

Abstract: Morphology is used to study the structures of the human body in Rachana Sharir. Activities are created based on the structures created by Saptdhatu. The necessary physiology forms the composition of the body. Since these structures are described through actual physical examination, the concepts of Sushrut Samhita, which are physically superior, are more scientific than other samhita literature. Therefore, the Sushrut Samhita is the yardstick for identifying dubious body formations. Snayu sur grava kehaosa. Seda mainitakse mitu korda Samhitas. Marmast, Agnikarmast, Shastra Karmast, Bandh Karmast, Sivan Karmast, Siravedhast kaj Vatvikarast mainitakse Snayu.
Waste Plastic Induced in Self Compacting Concrete to Avoid Plastic Pollution
Authors: Manikandan M. , Ramasamy Dr. V. , Selvakmar S.
Published: October 2023

Abstract: In this present study the plastic aggregate obtained from E-waste is used as a partial replacement of coarse aggregate in self-compacting concrete. An experimental investigation on the fresh, hardened characteristics of concrete using M40 grade of Self compacting concrete are carried out by casting standard concrete with various volume fractions of plastic aggregate such as 0%, 10%, 20%, 30%, 40%, 50% to determine optimal dosage. The fresh properties of SCC reveal that the workability of concrete are improved by using plastic aggregate. Strength properties such as compressive strength shows that up to 30% substitution of coarse aggregate there is no major change in compressive strength as compared to normal concrete. Beyond that there is drop in compressive strength for 50% replacement of coarse aggregate by plastic aggregate. Split tensile strength, Flexural strength and Young modulus of concrete increases for 10% plastic aggregate. Beyond that strength decreases upto 50% replacement. Impact strength decreases for all replacement levels.
Fetal ECG Monitoring System Based on the Android Smartphone
Authors: Lakshmidevi Mrs. B. , Indira Mrs. S
Published: October 2023

Abstract: Fetal movement (FM) monitoring is considered an important part of fetal well-being assessment due to its association with several fetal health conditions. Present methods of frequency modulation quantification, e.g., ultrasonography, MRI, and cardiotocography are limited to their use in the clinical setting. In this proposed system, he evaluates the performance of a lowcost, wearable FM monitor based on an acoustic sensor that pregnant women can use at home. A thresholding-based signal processing algorithm is developed for data analysis, which combines the outputs from all sensors and automatically detects FM. Finally, the spike morphology of the acoustic signals corresponding to the actual detected motions is found in the time-frequency domain through spectrogram analysis, which is expected to be useful for developing a more advanced signal processing algorithm to further improve the detection accuracy
Diálogos da cidade: deslocamentos entre o rural e o urbano
Authors: Jaques Ribeiro Cristine , de Garcia Nunes Tiago
Published: October 2023

Deslocar é poder encontrar outros modos de existir na cidade, modos heterogêneos, modos teimosos e intempestivos, modos que escancaram a negação do acesso aos direitos sociais e humanos. Mas, como se deslocar dentro da cidade formal? Como se deslocar dentro da cidade legal? O regular e o legal existem mais que o irregular e o ilegal? Essas perguntas orientam a problematização de temáticas que compõem a cidade, cujo objetivo é também deslocar para epistemes críticas que denunciem a continuidade do colonialismo e da colonialidade. Concordamos que a ciência poderá impedir processos de transformação social ou poderá contribuir para que os processos de transformação aconteçam por meio da denúncia das diversas desigualdades, sejam elas territoriais, sociais, econômicas, políticas, religiosas e culturais. Nessa linha conflitual, entre produção e reprodução do conhecimento, Diálogos da cidade vem se propondo a instigar processos críticos e analíticos de como as populações, as/os usuárias das políticas e as/os agentes dos direitos sociais vêm sendo tratadas e tratados por gestões públicas e privadas, conselhos de direitos e políticas públicas sociais. Quando destacamos os deslocamentos entre o rural e o urbano, afirmamos que partimos da problematização da questão agrária, como questão central. Sendo assim, todos os temas de estudo e de pesquisa têm sua origem na análise do início da implantação da propriedade privada, instituída pelo colonialismo e mantida no discurso da colonialidade, até os dias atuais e que tem, na financeirização da terra e na especulação imobiliária, sua permanência que é fortalecida diante do discurso de modernidade. A implantação da propriedade privada, reafirma a tradição escravocrata e, sendo assim, os temas que envolvem a vida são temas decorrentes desse processo histórico demarcado pelo sistema patriarcal e racista. Portanto, o conjunto de capítulos apresenta as dimensões raça, gênero, sexualidade e classe como orientadores da escrita coletiva.
THE LEGALITY OF BUYING AND SELLING WITHOUT KHIYAR RIGHTS UNDER ISLAMIC COMMERCIAL LAW
Authors: Khairunnisak
Published: October 2023

Buying and selling is an activity that often occurs such as in markets, supermarkets and other places to fulfil everyone's needs. One of the elements in buying and selling transactions is the right of khiyär. Khiyar is a permissibility in Islamic Shari'ah to find a good between two, namely to continue or to cancel the sale with the aim of avoiding disputes between the seller and the buyer in the future. However, not all buying and selling places impose khiyar rights for buyers, therefore this research aims to find out how Islamic law reviews buying and selling without khiyar rights. Buying and selling without khiyar rights is still considered valid because khiyar is not a valid condition in buying and selling. Khiyar is an option or choice that can be an alternative to achieving benefits for both parties, namely the seller and the buyer so that no party feels disadvantaged in the future. Suggestions from the author that business actors are expected to apply business ethics in accordance with Islamic law and applicable legislation in Indonesia and for buyers to be more careful before buying goods so as not to be harmed.
Pengaturan Hukum Internasional Terhadap Limbah Makanan dan Dinamikanya di Indonesia
Authors: Zuhra Amalia , Angkasari Wildani
Published: October 2023

The problem of food waste has become one of the increasingly concerning environmental issues in Indonesia. Improperly managed food waste, such as air, water, and soil pollution, can negatively impact the environment. This article aims to discuss the impacts of food waste on the environment, international legal regulations related to the issue, and the latest developments in Indonesia in addressing food waste. The research method used in this study is a literature review using scientific journals, books, and related documents. The results show that food waste can cause severe environmental damage and needs to be addressed seriously. Countries have adopted several international legal rules to address the problem of food waste, such as the Basel Convention and the Stockholm Declaration. In Indonesia, efforts to address food waste have been made, such as by promoting food waste reduction through education campaigns and waste recycling programs. However, more significant and integrated efforts are needed from the government, society, and private sector to address the problem of food waste effectively. In conclusion, this article emphasizes the need for coordinated and comprehensive action to address the increasingly concerning problem of food waste at the local and global levels.
Keywords: international law; food waste; environment
Border Area Management: How Should Indonesia Reform?
Authors: Darajati Muhammad Rafi , Syafei Muhammad , Sudagung Adityo Darmawan
Published: October 2023

This article examines how state territorial regulation can encourage development in Indonesia's border regions. This article also tries to explain the need for better management of borders between countries because there are several obstacles in implementing cross-border regulations. This research uses qualitative methods by taking the perspective of international law and constitutional law and collecting data through field research and reviewing related literature. Field research was carried out for 3 months by conducting in-depth interviews with several informants. Secondary data was obtained from reviewing books, journals, writings and mass media regarding international law, international relations and constitutional law. This research shows that the idea of ​​reforming border management between countries must be based on several aspects, namely law, institutions, development approaches and spatial planning.
Keywords: border area management; governance; state territory
Oxidation method using H2O2 on leachate from wastewater treatment plant inlet of Bantargebang integrated waste processing unit
Authors: Ursada Riang , Jidan Alfani Zahid , Bagastyo Arseto Yekti
Published: October 2023

Leachate produced from old landfills has a low level of biodegradability making it suitable for physico-chemical treatment. Low level of biodegradability is characterized by a concentration ratio of BOD5/COD ≤ 0.1. The leachate at the Bantargebang Integrated Waste Management Unit (UPST) has a BOD5/COD concentration ratio of 0.05. The current state of processing leachate at a wastewater treatment plant (IPAS) employs biological processing technology. This research uses inlet leachate from IPAS 3 UPST Bantargebang, with a batch system reactor. The reactor is a glass beaker with capacity of 1 L, operated using a magnetic stirrer with a stirring speed of 200 rpm. The reactor is covered with aluminum foil to prevent oxidation caused by light. The dosage used is based on H2O2/COD concentration ratios, which are 1.0625 and 2.125. Reactions time applied are 60 minutes and 180 minutes. The initial pH levels of the leachate used are 5, 6, 7 and 8. The variations which has optimum values are at pH 6, H2O2/COD 2.125, and a 60-minutes reaction time, resulting in average color removal, BOD5, COD, TSS, TN, and H2O2 reacted by 65%.
Análisis de la auditoría de gestión en el proceso contable en importadoras de repuesto automotriz en la ciudad de Guayaquil periodo 2020
Authors:   Instituto Superior Tecnológico Vicente Rocafuerte, Lino Pincay Hellen Briggitte , Rivera Guerrero Alvaro ,   Instituto Superior Tecnológico Vicente Rocafuerte
Published: October 2023

La Auditoría de Gestión está enfocada directamente a medir los niveles de eficiencia, eficacia y economía de una organización para determinar si existen deficiencias o desviaciones que estén afectando el normal desarrollo de las operaciones. El desarrollo de toda empresa en constante rendimiento deben de existir mejoras en todos los procesos contables como inventarios, bodega, mercaderías, por mal cruce de información, un incorrecto conteo existe un desequilibrio eminente en áreas de la comunicación que se presenta en el área administrativa, es por ello que la necesidad de agilitar las requisiciones y que el proceso contable a través de una Buena gestión de auditoría, sean desarrollado con su plenitud en el desglose de pedido y conozca la numeración de cada repuesto deben de conocer el uso que le cliente le va a dar a cada uno de las variedades de repuestos. El sector automotriz en el Ecuador posee una gran contribución dentro de la economía activa del país, por los ingresos que generan su comercialización, ventas, ensamblajes de automotores. La investigación evaluó el tipo de control interno que se realiza en la empresa en cuestión, las actividades que se realizan dentro del departamento de Inventarios y de bodega, y también se indagó si se llevaba un tipo de metodología para la administración de Inventarios.
Proceso contable y su incidencia en la rentabilidad post pandemia en la empresa Fishecuador de la ciudad de Guayaquil, año 2022
Authors:   Instituto Superior Tecnológico Vicente Rocafuerte, Miño Medina Víctor Andrés , Estefano Almeida Miguel Alejandro ,   https://orcid.org/0000-0003-4246-8958
Published: October 2023

El trabajo de investigación titulado “PROCESO CONTABLE Y SU INCIDENCIA EN LA RENTABILIDAD POST PANDEMIA EN LA EMPRESA FISHECUADOR DE LA CIUDAD DE GUAYAQUIL, AÑO 2022” se realizó con la finalidad de analizar su proceso contable y conocer sobre la rentabilidad que presenta el negocio, así podremos ver los resultados de la inversión que puso en el para ello todos los movimientos financieros de un negocio deben ser registrados y procesados con exactitud para luego poder analizar a través de los estados financieros y así medir la rentabilidad del negocio. La investigación realizada, cuyo objetivo fundamental se basó en, verificar el proceso contable y su incidencia en la rentabilidad, se lo desarrolló con información concedida por la propietaria de la empresa FISHECUADOR, basándose en las generalidades del negocio y el marco teórico que contiene definiciones, principios, fases que guardan relación con el proceso contable y la rentabilidad. La metodología se lo realizó con el método deductivo. Es un proyecto de dos tipos de investigación, de campo y documental, las técnicas manejadas fueron observación y entrevista dirigida al personal responsable del negocio. Los resultados obtenidos se los presenta al final del trabajo investigativo en donde se emiten las conclusiones y recomendaciones a las que se ha llegado.
Aplicación de la NIC 2 y su incidencia del control interno en la importadora Miguev Sa. Ltda. De la ciudad de Guayaquil, año 2021
Authors:   Instituto Superior Tecnológico Vicente Rocafuerte, Risco Pesantez Melanye Jelena , Rivera Pizarro Cinthya ,   Instituto Superior Tecnológico Vicente Rocafuerte
Published: October 2023

Esta investigación se desarrolló con el objeto de Determinar la incidencia de la aplicación de la NIC 2 en el control interno de los inventarios en la importadora MIGUEV SA. LTDA. de la ciudad de Guayaquil, año 2021, implementando en él, la Norma Internacional de Contabilidad 2 – Inventarios y mejorando de esta manera su sistema de control interno en los almacenes. Esto permitirá; un excelente monitoreo de las actividades efectuadas en el área de almacén, la facilidad de los registros y validación contable y sobre todo la toma de decisiones y la optimización de los costos del negocio. Para cumplir con este objetivo se realizó una investigación de tipo descriptiva-correlacional y con un diseño no experimental, teniendo como población de la importadora MIGUEV SA. LTDA., cuya muestra son sus Estados Financieros y sus tres trabajadores; se emplearon herramientas como la observación y cuestionario para la recolección de datos. Llegando a la conclusión, que aplicando la NIC 2, mejoró el cumplimiento del control interno en la importadora MIGUEV SA. LTDA., ayudando al área de almacén a reconocer sus funciones, el manejo del sistema Kardex y teniendo mayor confiabilidad y veracidad en la información reflejada en los Estados Financiero.
Utilizing the CROPGRO Simulation Model to Optimize Management Practices for Achieving High Soybean Yields
Authors: Negi Ankita , Rana Kuldeep , Ranjan Rajeev
Published: October 2023

A study was conducted during the kharif (June–September) season of 2018 at G.B.P.U.A.&T., Pantnagar, Uttarakhand, India to calibrate and validate the CROPGRO-soybean model for Terai region and determine the optimal management practices for soybean variety PS1347. The experiment followed a Two Factorial Randomized Block Design, involving two fertilizer treatments with three sowing dates replicated thrice. The CROPGRO model was calibrated and validated using the field data of 2018 and 2017, respectively. The RMSE% between the observed and simulated values of different crop stages and yield indicators were between 3.24% and 14.22%. Subsequently, the crop yield for different management practices was also simulated. The model encompassed yield simulations for various management practices viz., six tillage methods, five fertilizer treatments, nine sowing dates, and six irrigation levels. To achieve error minimization, soybean yield was simulated for four consecutive years (2015–2018) under various management practices, and the data was averaged. The simulation results indicated that the optimal management practices for achieving the highest soybean yield include sowing the seeds on the 20th June after implementing a tillage regimen involving three ploughings and two harrowing operations and further nourishing the crop with fertilizer dose of N:P:K:S::25:60:40:20 and applying 90 mm of irrigation. These findings will aid in optimizing management practices and developing sustainable and efficient approaches to achieve higher soybean yields with minimal inputs.
Goal Free Evaluation
Authors: Halima Raden Ayu , Mustofa Triono Ali
Published: October 2023

Evaluasi bebas tujuan atau Goal Free Evaluation (GFE) adalah pendekatan evaluasi di mana evaluator melakukan evaluasi tanpa mengacu pada tujuan dan sasaran yang telah ditentukan sebelumnya. Alasan di balik GFE adalah bahwa evaluator harus memeriksa semua hasil yang relevan; selain itu, tujuan dan sasaran yang dinyatakan hanya mewakili sejumlah hasil potensial yang terbatas. Selanjutnya, jika suatu program mencapai tujuannya, maka tujuan dan sasaran harus jelas, jika tidak, tujuan tersebut tidak relevan. Evaluator bebas tujuan hampir selalu berada di luar program dan pemangku kepentingannya untuk memastikan ketidaktahuan tentang tujuan yang dinyatakan; dengan demikian, evaluator bebas tujuan dengan sengaja menghindari mengetahui tujuan program atau mengabaikannya. Kelebihan dan kekurangan pada evaluasi bebas tujuan menjadi polemik penting dalam penentuan model evaluasi. Pada artikel ini akan dibahas lebih lanjut mengenai model evaluasi bebas tujuan.
Evaluasi Model CIPP Dalam Pembelajaran Tahfidz al-Quran Di Pendidikan Ulama Tarjih Muhammadiyah (PUTM)
Authors: Muzakki Fadhlurrahman Rafif , Mustofa Triono Ali
Published: October 2023

Penelitian ini bertujuan mengetahui hasil evaluasi model CIPP dalam pembelajaran tahfidz di Pendidikan Ulama Tarjih Muhammadiyah Putra yang meliputi evaluasi context, input, process dan product. Dengan menggunakan metode penelitian kualitatif jenis penelitian lapangan (field reserch). Teknik pengumpulan data dengan cara observasi, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa: pertama, pengelolaan pembelajaran tahfidz di PUTM sudah cukup efektif. Hal ini terlihat dari jadwal kegiatan yang sudah tersistematis dalam silabus PUTM. kedua, fasilitas pembelajaran yang representatif dan pembinaan yang intensif dapat menunjang tujuan akhir dari pembelajaran tahfidz. Ketiga, capaian peserta didik dalam pembelajaran tahfidz sudah baik, dilihat dari hasil ujian tengah semester gasal dan ujian akhir semester gasal tahun akademik 2022/2023.
PERAN ORANG TUA DALAM MENINGKATKAN MOTIVASI BELAJAR AGAMA
Authors: Sholeh Muhammad , Azani Mohammad Zakki , Hidayat Rahmat
Published: October 2023

This study aims to determine how the efforts of parents to increase the motivation to learn Religion in adolescent teeneger. This research is motivated because nowadays there are many parents who have difficulty in motivating their teeneger to study Religion, or even difficulties in teaching Religion to their teeneger, due to influences from the environment, associations or influences from within the child. This can lead to negative actions like online game addiction, adultery, etc. Therefore, parents must continue to strive to motivate their children to study religion, so that children can avoid these negative actions. The research was carried out in Kusumodilagan Village, Joyosuran Village, Pasar Kliwon District, Surakarta, precisely in RW 12. The type of research that will be conducted is field research. The approach that will be used in this research is a qualitative phenomenological approach through case study research. In obtaining valid data to support research needs, researchers used the methods of observation, interviews, and documentation in the data collection process. Data analysis techniques that will be used in this study apply data reduction techniques, data presentation and conclusion drawing and data verification. Then, to ensure the validity of the data and the retrieval, the technique triangulation and source triangulation are used. This study concludes that the efforts of parents start from showing attention, being a good exemple and encouranging children, meeting needs and giving gifts or punishment for their children. Meanwhile, the findings of the constraints and solutions of parents' efforts in increasing motivation to learn Religion are based on two factors, namely factors whose influence comes from within (interistic) and factors whose influence comes from outside (exteristic).
دور مدير المدرسة في إنجاز تعليم المدرسين بالمدرسة الحكومية لذوي الحاجة الخاصة سراغين جاوى الوسطى العام
Authors: Shohib Muhammad Wildan , Margatama Pandang
Published: October 2023

يتم تحديد نجاح تعليم المدرسين إلى حد كبهم على نجاح مدير المدرسة وإدارة العاملين في مجال التعليم المتاحة في المدرسة. مدير المدرسة له دور هام في تحسين نجاح التعليم في المدرسة. مدير المدرسة هو المسؤول الأول لتنظيم الأنشطة التعليمية والإدارة المدرسية والتدريب العاملين في مجال التعليم. ويجب أن يقوم مدير المدرسية بالقيادة في تحسين إنجاز التعليم في المدرسة، لذلك يجب أن يكون لمدير المدرسة الشخصية الجيدة والقدرة والمهارات اللازمة ليقود العمل المدرسي اللازم في المدرسة. يهدف هذا البحث إلى: (1) الكشف عن أحوال إنجاز تعليم المدرسين بالمدرسة الحكومية لذوي الحاجة الخاصة سراغين جاوى الوسطى. (۲) الكشف عن دور مدير المدرسة في إنجاز تعليم للمدرسين بالمدرسة الحكومية لذوي الحاجة الخاصة سراغين جاوى الوسطى. ويكون نوع هذا البحث بحث علمية كيفي باستخدام الطريقة الوصفية، والمناهج المستخدمة لجمع البيانات في هذا البحث هي: (1) منهج المقابلة (Interview) (2) ومنهج الملاحظة لاشتراك سلمي (Passive Participation) (3) والوثائق المكتوبة (Documentary). وأما تحليل البيانات الذي استخدمه هذا البحث هو تحليل البيانات من منهج مليس و هوبيرمان (Huberman mile) تشمل على ثلاث خطوات وهي: (1) تحفيض البيانات (2) عرض البيانات (3) والاستنباط. وبينما نتائج هذه الدراسة وهي: (1) إنجاز تعليم المدرسين بالمدرسة الحكومية لذوى الحاجة الخاصة مراغين جاوى الوسطى، وتلك إنجاز تتكون من: أ- القدرة على جعل التخطيط والإعلام للتدريس، ب-لازم أن يستعيب المدرسين المادة قبل التعليم، ج- لازم على المدرسين إستيعاب المنهج الدراسي وفن التدريس، د- يجب على المدرس إعطاء الواجبات المنزيلية للطلبة، هـ- قدرة المدرسين في تنظيم الإدارة المدرسية، و- لازم على المدرسين القدرة على الإنتاج والتقييم. (۲) وأما دور مدير المدرسة في إنجاز تعليم المدرسين بالمدرسة الحكومية لذوى الحاجة الخاصة سراغرين جاري الوسطى: أ- كان مدير المدرسة قدوة حسنة للمدرسين والتلاميذ، عقد الإجتماع الأسبوعي كل يوم الإثنين، مدير المدرسة القيام بتنظيم الأعمال المدرسي، ب-مدير المدرسة هو المسؤول الأول لتنظيم أعمال المدرسة والمنهج الدراسي، ج- ترقية كفاءة المدرسين خصوصا في التدريس. د- قام مدير المدرسة بتفتيش إعداد التدريس للمدرسين قبل القيام بالتدريس. ه-تقديم التوجيه للمعلمين خاصة في تحسين كفاءة المعلمين في تعليم الأطفال ذوي الاحتياجات الخاصة، ذ- يوفر المدير التسهيلات والراحة في تطوير كفاءة المعلم، ز- عقد المدير اجتماعات أسبوعية لتقييم أداء المعلم.
ADAB PENCARI ILMU DAN STRATEGINYA DALAM KITAB HILYAH THALIB AL-‘ILMI
Authors: Muzakki Fadhlurrahman Rafif
Published: October 2023

Penelitian ini bertujuan untuk menganalisis adab dan strategi pencari ilmu dalam kitab Hilyah Thalib al-‘Ilmi karya Bakr bin Abdullah Abu Zaid. Ini merupakan penelitian kualitatif dengan jenis penelitian kepustakaan. Sumber primer yang dijadikan rujukan adalah kitab Hilyah Thalib al-‘Ilmi karya Bakr bin Abdullah Abu Zaid. Adapun teknik pengumpulan menggunakan cara dokumentasi, sedangkan untuk menganalisisnya digunakan penelitian yang bersifat deskriptif-analisis.Hasil penelitian ini menunjukan bahwa: 1) Adab pencari ilmu menurut Bakr bin Abdullah terdapat empat adab; adab terhadap diri sendiri, adab terhadap guru, adab berteman dan adab dalam kehidupan ilmiah. 2) Adapun strategi pencari ilmu menurut Bakr bin Abdullah ialah dengan cara; pertama, menghafalkan ringkasan materinya. Kedua, memeriksa hafalan dengan gurunya. Ketiga, tidak menyibukan diri dengan buku-buku tebal, sebelum benar-benar menguasai kaidah-kaidah dasar. Keempat, tidak berpindah kepada ringkasan lain tanpa alasan yang jelas. Kelima, berupaya mencari faidah-faidah dan kaidah-kaidah ilmiah. Keeman, Totalitas dalam mencari dan meningkatkan keilmuanKey-Word : Adab, Strategi, Pencari Ilmu.
Kontribusi PCM Dalam Gerakan Dakwah Keagamaan Di Islamic Center Muhammadiyah Cabang Blimbing
Authors: Imani Syahda Luthfiah , Rizki Naila , Azani Mohammad Zakki
Published: October 2023

Penelitian ini bermula dari latar belakang Desa Wonorejo yang merupakan kawasan organisasi Muhammadiyah yang diposisikan untuk menyebarkan ajaran Islam. Pimpinan Cabang Muhammadiyah Blimbing mengembangkan kegiatan keagamaan yang berada di Islamic Center Muhammadiyah Cabang Blimbing. Jenis penelitian yang digunakan adalah penelitian lapangan yang bersifat kualitatif. Teknik pengumpulan datanya melalui observasi, wawancara dan dokumen. Adapun teknik analisis datanya dengan cara mereduksi data, penyajian data dan penarikan kesimpulan. Berdasarkan hasil penelitian delapan jenis majelis pimpinan cabang Muhammadiyah Blimbing mempunyai tugas dan kontribusi yang berbeda-beda dalam hal kegiatan dakwah keagamaan di Desa Wonorejo.Faktor pendukung perkembangan Islam yang saat ini merebak dimana-mana itu menjadikan Muhammadiyah lebih maju dan berkembang pesat, masyarakat dan lingkungan yang baik memberikan dukungan dan sokongan. Faktor penghambat antara partisipasi masyarakat lain dalam kegiatan keagamaan yang menurun khususnya anak-anak dan remaja, Ekonomi yang berkaitan dengan keuangan kegiatan dakwah keagamaan yang sangat membutuhkan dana besar pengkaderan dimana kesulitan untuk mencari generasi yang siap dengan kegiatan dakwah keagamaan, lawan politik yang tidak menyukai politik diMuhammadiyah sejak lahir,Ormas lain yang iri dengan perkembanganMuhammadiyah yang sangat besar dan menimbulkan perpecahan.