COVAD survey 2 long-term outcomes: unmet need and protocol
Authors: Fazal Zoha Zahid , Sen Parikshit , Joshi Mrudula , Ravichandran Naveen , Lilleker James B. , Agarwal Vishwesh , Kardes Sinan , Kim Minchul , Day Jessica , Makol Ashima , Milchert Marcin , Gheita Tamer , Salim Babur , Velikova Tsvetelina , Gracia-Ramos Abraham Edgar , Parodis Ioannis , Nikiphorou Elena , Tan Ai Lyn , Chatterjee Tulika , Cavagna Lorenzo , Saavedra Miguel A. , Shinjo Samuel Katsuyuki , Ziade Nelly , Selva-O’Callaghan Albert , Nune Arvind , Knitza Johannes , Kuwana Masataka , Gutiérrez Carlos-Enrique Toro , Caballero-Uribe Carlo Vinicio , Dey Dzifa , Distler Oliver , Chinoy Hector , Agarwal Vikas , Aggarwal Rohit , Gupta Latika ,   COVAD Study Group, Barman Bhupen , Singh Yogesh Preet , Ranjan Rajiv , Jain Avinash , Pandya Sapan C , Pilania Rakesh Kumar , Sharma Aman , M Manesh Manoj , Gupta Vikas , Kavadichanda Chengappa G , Patro Pradeepta Sekhar , Ajmani Sajal , Phatak Sanat , Goswami Rudra Prosad , Chowdhury Abhra Chandra , Mathew Ashish Jacob , Shenoy Padnamabha , Asranna Ajay , Bommakanti Keerthi Talari , Shukla Anuj , Pandey Arun Kumar R , Gaur Prithvi Sanjeevkumar , Mamadapur Mahabaleshwar , Ghodke Akanksha , Chandwar Kunal , Jagtap Kshitij , Fazal Zoha Zahid , Cansu Döndü Üsküdar , Yıldırım Reşit , Patel Aarat , Pauling John D , Wincup Chris , Giannini Margherita , Maurier François , Campagne Julien , Meyer Alain , Del Papa Nicoletta , Sambataro Gianluca , Fabiola Atzeni , Govoni Marcello , Parisi Simone , Bocci Elena Bartoloni , Sebastiani Gian Domenico , Fusaro Enrico , Sebastiani Marco , Quartuccio Luca , Franceschini Franco , Sainaghi Pier Paolo , Orsolini Giovanni , De Angelis Rossella , Danielli Maria Giovanna , Venerito Vincenzo , Grignaschi Silvia , Giollo Alessandro , Traboco Lisa S , Shaharir Syahrul Sazliyana , Wibowo Suryo Anggoro Kusumo , Tehozol Erick Adrian Zamora , Serrano Jorge Rojas , La Torre Ignacio García-De , Colunga‑Pedraza Iris J. , Colunga‑Pedraza Iris J. , Merayo-Chalico Javier , Loarce-Martos Jesús , Prieto-González Sergio , Gil-Vila Albert , Aranega Raquel , Hoff Leonardo Santos , Nakashima Ran , Sato Shinji , Kimura Naoki , Kaneko Yuko , Tomaras Stylianos , Proft Fabian Nikolai , Holzer Marie-Therese , Gromova Margarita Aleksandrovna , Aharonov Or , Nagy-Vincze Melinda , Griger Zoltán , Hmamouchi Ihsane , El bouchti Pr Imane , Baba Zineb , Ima-Edomwonyi Uyi , Dedeke Ibukunoluwa , Airenakho Emorinken , Madu Nwankwo Henry , Yerima Abubakar , Olaosebikan Hakeem , Chibuzo Okwara Celestine , A Becky , Koussougbo Ouma Devi , Palalane Elisa , Langguth Daman , Limaye Vidya , Needham Merrilee , Srivastav Nilesh , Hudson Marie , Landon-Cardinal Océane , Zuleta Wilmer Gerardo Rojas , Arbeláez Álvaro , Cajas Javier , Silva José António Pereira , Fonseca João Eurico , Zimba Olena , Bohdana Doskaliuk , So Ho , Ugarte-Gil Manuel Francisco , Chinchay Lyn , Bernaola José Proaño , Pimentel Victorio , Tanveer Hasan A. T. M. , Saha Sreoshy , Vaidya Binit , Fathi Hanan Mohamed , Mohammed Reem Hamdy A , Chen Yi-Ming , Harifi Ghita , El Kibbi Lina , Halabi Hussein Mohammed , Akawatcharangura P , Katchamart Wanruchada , Fuentes-Silva Yurilís , Cabriza Karoll , Losanto Jonathan , Colaman Nelly , Cachafeiro-Vilar Antonio , Bautista Generoso Guerra , Ho Enrique Julio Giraldo , González Raúl Agustín , Nunez Lilith Stange , M Cristian Vergara , Báez Jossiell Then , Alonzo Hugo , Pastelin Carlos Benito Santiago , Salinas Rodrigo García , Obiols Alejandro Quiñónez , Chávez Nilmo , Ordóñez Andrea Bran , Argueta Sandra , Quijivix Daniel , Llerena Gil Alberto Reyes , Sierra-Zorita Radames , Arrieta Dina , Hidalgo Eduardo Romero , Saenz Ricardo , M. Idania Escalante , Morales Roberto , Calapaqui Wendy , Quezada Ivonne , Arredondo Gabriela 
Published: August 2022

Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, and antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy to manage pandemic. Although none of the currently approved vaccines are live-attenuated, several reports of disease flares, waning protection, and acute-onset syndromes have emerged as short-term adverse events after vaccination. Hence, scientific literature falls short when discussing potential long-term effects in vulnerable cohorts. The COVAD-2 survey follows on from the baseline COVAD-1 survey with the aim to collect patient-reported data on the long-term safety and tolerability of COVID-19 vaccines in immune modulation. The e-survey has been extensively pilot-tested and validated with translations into multiple languages. Anticipated results will help improve vaccination efforts and reduce the imminent risks of COVID-19 infection, especially in understudied vulnerable groups.