bluuebunny/crossref_metadata_2025 huggingface dataset:
Le Rôle de l’Identification chez l’Adolescent Exposé à la Violence Conjugale au Cameroun
Authors: Rocard Tabue Defo Fabrice , Garance Kameni Ngaleu Achille
Published: June 2024

Marital violence in Cameroon is a growing scourge but, curiously, experienced in many families as a banality. Unfortunately, this violence between parents (verbal, physical, psychological, economic and spiritual) is practiced in the presence of adolescents. This presence of adolescents will create psychological suffering for them. This suffering will subsequently be evacuated by the psychic. It is in this movement that our study focuses on the process of evacuating psychological suffering in adolescents exposed to marital violence. The clinical method was used as a research method. The interviews were carried out with three adolescents frequently exposed to marital violence in Cameroon. The data collected from the subjects were analyzed through thematic content analysis following the psychoanalytic approach. It appears from the interviews semi-structured that Cameroonian adolescents exposed to marital violence are affected on their psychic. However, these adolescents, faced with this adversity, mobilized psychic energy based on identification with peers not exposed to marital violence to relieve psychological suffering. The fact that the adolescent identifies with unexposed peers will restore psychological balance.
Qualitative Analysis of 405 Life Stories from Children Working in the Worst Forms of Child Labour in Bangladesh
Authors: Cannon Mariah , Afroze Jiniya , Burns Danny , Muhsina Mushtari , Aktar Afrin , Azman Ali , Hossain Khandaker Reaz , Kundu Surojit , Macleod Shona , Maksud A.K.M. , Paul Sukanta , Rasel Md. , Raw Anna , Sayed Sayma , Sayem Mashrique , Sharmin Nusrat , Tabassum Tanzila , Uddin Forhad , Zabed Asif
Published: June 2024

The CLARISSA (Child Labour: Action-Research-Innovation in South and South-Eastern Asia) programme is a five-year, action research consortium generating evidence-informed, innovative solutions by children to avoid hazardous, exploitative labour in Bangladesh and Nepal. This paper is based on a qualitative analysis of 405 life stories collected from child labourers in Bangladesh working in the worst forms of child labour in the leather sector or living in leather sector neighbourhoods. Our analysis of their stories provides a rich picture, from children’s perspectives, of the drivers of child labour, views of child labour, working conditions, and their lives outside of work. The paper also explores the complexity, nuance, and interaction within these themes, drawing on and highlighting the diversity of experience articulated in the stories.
Simulation Structure for Selecting an Optimal Error Distribution Through the GAS Model
Authors: Samuel Richard T. A. , Chimedza Charles , Sigauke Caston
Published: June 2024

In econometrics and finance, volatility modelling has long been a specialised field for addressing a variety of issues that pertain to the risks and uncertainties of an asset. However, volatility modelling for risk management is highly dependent on the underlying error distribution. Hence, this study presents a Monte Carlo simulation (MCS) structure for selecting an optimal or the most adequate error distribution that is relevant for modelling the persistence of volatility through the Generalized Autoregressive Score (GAS) model. The structure describes an organised approach to the MCS experiment that includes “background of the study (optional), defining the aim of the study, specifying the research questions, method of implementation, and summarised conclusion”. The method of implementation is a process that consists of writing the simulation code, setting the seed, setting the true parameter a priori, data generation, and performance evaluation throughmeta-statistics. Among the findings, the study used both fat-tails and √N consistency experiments to show that the GAS model with a lower unconditional shape parameter value (ˆν∗ = 4.1) can generate a dataset that adequately reflects the behaviour of financial time series data, relevant for volatility modelling. This dynamic structure is intended to help interested users on MCS experiments utilising the GAS model for reliable volatility persistence calculations in finance and other areas.
Kültür ile Kanıtlanmış Tüberküloz Vakalarının İlaç Duyarlılıklarının Retrospektif Analizi
Authors: Kaya Arda , Çavuşoğlu Cengiz , Başkol Dilşah , Işıkgöz Taşbakan Meltem
Published: June 2024

Amaç: Çalışmamızda, Ocak 2018- Ocak 2023 yılları arasında üçüncü basamak bir üniversite hastanesi mikobakteriyoloji laboratuvarında klinik örneklerde M.tuberculosis complex üremesi saptanan hastaların direnç profilleri ve klinik özelliklerinin retrospektif olarak değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntem: 2018-2023 yılları arasında kabul edilen klinik örneklerden (balgam, bronkoalveolar lavaj, doku vb.) M.tuberculosis compleks üremesi olan hastaların demografik verileri, enfeksiyon tutulum yeri ve ilaç direnç paternleri hastane veri tabanındaki kayıtlarından retrospektif olarak incelenmiştir.
Bulgular : Çalışmaya 204 hasta dahil edilmiştir, hastaların %6,86’sında (n= 14) izoniyazid (INH) direnci, %2,45’inde (n= 5) streptomisin direnci saptanmıştır. Bu hastaların ikisinde izoniyazid ve streptomisin direnci birlikte saptanmıştır. Rifampisin direnci, etambutol direnci ve ÇİD-TB saptanmamıştır. Tüberküloz tutulum yeri en sık %68,1 (n= 139) ile akciğer olarak saptanmıştır
Sonuç: Tüm dünyada morbidite ve mortalitenin önemli nedenlerinde biri olmaya devam eden tüberküloz gelişen tıp teknolojisine rağmen hala eradike edilememiştir. Tedavi süresi, hasta uyumu ve gereksiz antibiyotik kullanımı nedeniyle gün geçtikçe artan ilaç direnci, klinik pratikte hekimleri zorlamaktadır. Tüberkülozun Edinilmiş Bağışık Eksikliği Sendromu tanımlayıcı hastalıklar arasında olması nedeniyle, ilaç direnci sorununun yanında İnsan Bağışıklık Yetmezliği Virüsü enfeksiyonu da her hekimin dikkat etmesi gereken diğer bir konudur. Çalışmamızda tüberküloz hastalarında HIV serolojisine yeteri kadar bakılmadığı görülmüştür.
A case report on unintentional ingestion of formaldehyde solution
Authors: Karakoyun Zeynep Nisa , Karakoyun Ömer Faruk , Yılmaz Sümeyye Gül , Golcuk Yalcin
Published: June 2024

Formaldehyde (FA) or formaldehyde solution, whose industrial name is formalin ad systematic name is methanal (CH2O), is an organic compound in the aldehyde structure. Industrially, FA is used for its preservative and sterilizing agent properties. Fish farms use FA solutions against bacterial diseases in juvenile fish, protect to fish, and for disinfection purposes. Although FA is a frequently used substance in the industrial, laboratory, and cosmetic fields, the literature is very scare in terms of toxic doses or symptoms in cases of oral intakes. This case describes the clinical course and wrong mismanagement acute oral FA ingesting.
The problem of cold start emissions from vehicles
Authors: Laskowski Piotr , Zimakowska-Laskowska Magdalena , Jan Matej , Wiśniowski Piotr
Published: June 2024

The progression of passenger vehicles is progressing, and regulations are continually being revised, resulting in a decrease in car exhaust emissions. The European Commission has revised the RDE test procedure to include exhaust emissions during a cold start, as part of package 3. The article carried out simulations using COPERT software, which uses tests based on WLTP, assuming ambient temperatures from -10◦C to +20◦C, at intervals of 5◦C. This paper aims to present the results of mathematically modelling the influence of ambient temperature on the cold-start emissions of carbon dioxide (CO2), nitrous oxide (N2O), methane (CH4), nitrogen oxides (NOx), non-methane volatile organic compounds (NMVOC), hydrocarbons (treated as Volatile organic compounds - VOC), total particulate matter (TSP) and particle number (PN) in passenger cars and light-duty vehicles. The modelling results show that a change in ambient temperature significantly affects carbon dioxide (CO2), nitrous oxide (N2O), methane (CH4), nitrogen oxides (NOx), non-methane volatile organic compounds (NMVOC), hydrocarbons (treated as Volatile organic compounds - VOC), total particulate matter (TSP) and particle number (PN) in cold-start emissions.
Avaliação epidemiológica da anemia infecciosa equina nas Américas
Authors: Torres Amanda da Silva , Oliveira Rafael Ovídio de , Neves Daniele Ahad das , Frias Danila Fernanda Rodrigues
Published: June 2024

Objetivou-se analisar o perfil epidemiológico da anemia infecciosa equina (AIE) nas Américas. Foi realizado um estudo transversal, descritivo, retrospectivo e quantiqualitativo, que utilizou como unidades de análise países localizados nas Américas. Os dados foram coletados a partir das informações disponíveis em banco de dados oficiais. No período estudado, nas Américas (exceto Brasil), foram notificados 74.932 casos. No Brasil, foram notificados, no mesmo período, 73.536 casos, com prevalência de 1,3 caso a cada 100 animais, destacando-se os estados do Ceará, Maranhão, Roraima e Alagoas. O estado do Ceará, Piauí e o Distrito Federal apresentaram a menor quantidade de casos por focos, o que demonstra maior dispersão da doença nesses estados. Conclui-se que o Brasil possui baixa prevalência de AIE notificada; porém, devido à importância da doença para o setor, devem ser executadas medidas de vigilância ativa da doença nos animais e ações de prevenção, no âmbito de Saúde Única.
Análise sobre os serviços da Rede de Atenção Psicossocial: uma revisão integrativa
Authors: Nabarrete Luiza Maria de Souza , Bastos Paulo Roberto Haidamus de Oliveira
Published: June 2024

A Reforma Psiquiátrica propiciou o surgimento de serviços substitutivos aos hospitais psiquiátricos para atendimento e acolhimento às pessoas em sofrimento psíquico. Assim, este artigo objetiva abordar a percepção desses serviços no cenário atual a partir das produções encontradas sobre o tema. A metodologia utilizada foi a Revisão Integrativa realizada nos principais bancos de dados no período de dez anos (2012 a 2022), que resultou na análise de 26 estudos. Considera-se que há um predomínio de pesquisas qualitativas e que, apesar dos avanços, a Rede de Atenção Psicossocial (RAPS) ainda parece esbarrar em constantes desafios, evidenciados pelo sucateamento dos serviços, que resultam em um trabalho em rede que é incipiente, em razão da falta de investimentos financeiros e humanos, e que apresentou uma piora a partir de 2017, devido a um projeto de governo que operava em um processo de desmonte e negligência, indo na contramão dos avanços conquistados nas últimas décadas.
Direitos humanos e crimes contra a honra na era digital
Authors: Pollak Fernanda Victorio , Borges Pedro Pereira
Published: June 2024

Este artigo aborda a temática dos crimes contra a honra na era digital e analisa como a legislação brasileira combate essas infrações. Com o avanço da tecnologia e o advento da internet, a disseminação de informações e o acesso rápido às redes sociais têm proporcionado um cenário propício para a propagação de ofensas e informações difamatórias. Nesse contexto, os crimes contra a honra - calúnia, difamação e injúria - ganham novas dimensões e desafios na era digital. Diante desse cenário, o objetivo central do presente trabalho é proporcionar uma análise aprofundada sobre os crimes contra a honra na Era Digital, elucidando suas características, o tratamento legal estabelecido pela legislação brasileira e a relação intrínseca com os Direitos Humanos. Buscar-se-á compreender como a evolução tecnológica tem influenciado a forma de perpetrar esses delitos e como o sistema jurídico deve adaptar-se a essa nova realidade, garantindo a proteção dos valores essenciais à convivência em sociedade. A metodologia empregada nesta pesquisa será de natureza bibliográfica, fundamentada em fontes qualitativas e quantitativas, com análise de doutrinas, artigos científicos, jurisprudências e normas legais pertinentes ao tema. Os resultados desta pesquisa apontam para a necessidade de uma legislação mais abrangente e atualizada para lidar com os crimes contra a honra na era digital. A evolução tecnológica trouxe novas formas de propagação das ofensas, como as redes sociais e aplicativos de mensagens, o que exige uma abordagem mais eficaz das autoridades legais na identificação e responsabilização dos infratores.
A pesquisa da sustentabilidade ambiental nos Planos de Iniciação Científica de uma IES pública
Authors: Nogueira Maria Aparecida Farias de Souza , Matos Josivan Aquino de , Almeida Vera Luci de
Published: June 2024

As pesquisas desenvolvidas na Iniciação Científica (IC) impulsionam investigar soluções para impasses em diversas áreas do conhecimento e, entre estas áreas, a sustentabilidade ambiental, que tem sido extensamente debatida nos últimos anos. Assim, tem-se como objetivo geral analisar o histórico dos Planos de Iniciação Científica, em uma Instituição de Ensino Superior (IES) pública, na pesquisa em Sustentabilidade Ambiental, entre 2006 e 2021. Seguiu-se um protocolo de análise e seleção nos títulos dos planos de IC, cadastrados na base de dados da Divisão de Iniciação Científica. A análise dos dados, com o uso predominante da estatística descritiva, identificou 4.374 planos, sendo que apenas 400 planos abordavam a sustentabilidade ambiental, ou seja, 9,14%. A maioria pertence às áreas de Engenharias, Biológicas e Agrárias (50,76%), com abordagem em diversos eixos temáticos, sendo resíduos (20,91%) o que mais se destacou nas pesquisas. Entre as modalidades, destaca-se o PIBIC (54,75%), que contempla bolsa fornecida pelo CNPq e pela IES.
Development of mobile application in dermatological and aesthetic dysfunction
Authors: Pinto Wellington , Cardoso Pedro Henrique de Oliveira , Migliolo Ludovico
Published: June 2024

The mostly Brazilian population present common disorders among young and adults peoples denominated aesthetic diseases, for example acne, melasma, psoriasis and nettle rash. Given this scenario, the development of a mobile application has become feasible, with technology growing exponentially, and, at the same time, there is also an increased interest for developing new ways of disseminating content in a practical way. In this study, the aim was to help nonprofessional, academics and health and aesthetic professionals. A large percentage were young people (74.7%), aged between 18 and 29 years old, but the target of the application is not exclusive to this profile. Our research resulted in good metrics, among them, the public studied is interested in paying to have the application on their smartphone. Thus, the virtual atlas of aesthetic dysfunctions demonstrated to be a tool for nonprofessional and professionals helping in the acquisition of information.
O tratamento do autismo na equoterapia
Authors: De Souza Luane Paula , Rotava Bruna
Published: June 2024

O transtorno do espectro autista (TEA) é um transtorno comportamental, considerado como uma desordem neurobiológica, que leva a alterações na interação social, dificuldade na expressão, na afetividade, afetando a forma como a criança vê o mundo. Definida pela Associação Nacional de Equoterapia (ANDE) como um método terapêutico e educacional, a equoterapia utiliza-se do cavalo como recurso terapêutico e tem como objetivo o desenvolvimento biopsicossocial dos sujeitos. O objetivo deste estudo consistiu em analisar os efeitos da equoterapia no tratamento do autismo. Nesta pesquisa, 4 crianças de ambos os sexos foram avaliadas por meio da aplicação da escala M-CHAT e atendidas por meio da equoterapia. Os resultados obtidos foram satisfatórios em 75% das crianças avaliadas, demonstrando a redução da pontuação na escala M-CHAT. Diante disso, a equoterapia constitui-se uma alternativa promissora de engajamento de crianças e familiares com TEA.
Gestão escolar em contexto vulnerável: gerenciando dados em prol da justiça social
Authors: Paiva-Pereira Alessandra Cristina Matheus de , Wandercil Marco , Garcia Paulo Sérgio , Nascimento Luís Lopes
Published: June 2024

O presente artigo tem como objetivo compreender como gestores de escolas localizadas em regiões de alta vulnerabilidade social conciliam os imperativos do gerencialismo às demandas necessárias à justiça social; além disso, contextualiza a aplicação desses princípios nos processos educacionais. Por meio de uma pesquisa de natureza exploratória e analítico-descritiva, apresenta uma análise proveniente de respostas de gestores de escolas públicas estaduais da região metropolitana do Grande ABC Paulista. Os resultados do estudo apontaram indícios que convergem para a articulação de uma liderança educacional não centralizadora, formada por sujeitos que compreendem o trabalho da gestão escolar como uma relação colaborativa e corresponsável, com compartilhamentos e tomadas de decisão construídos e mediados no cotidiano da escola, a partir dessas convergências. Ainda que alguns resultados mostrem divergências em relação a essa prática, verifica-se que termos como ‘gestão educacional’, ‘gerencialismo’, ‘boas práticas educacionais’, ‘desempenho’ e ‘performatividade’ incorporam o vocabulário e o cenário, fundindo as esferas pedagógicas e administrativas. Os resultados denotam que um diretor comprometido com a responsabilidade de compreender os dados de sua escola para além dos números, que mantenha uma liderança distribuída e participativa, possibilita a criação de um ambiente favorável ao trabalho, tanto para alunos quanto para professores.
A dinâmica relacional no “afrocentramento” do currículo: por uma política da diferença
Authors: Ribeiro William de Goes , Corrêa Diogo Silva , Silvestre Celma Fernandes
Published: June 2024

O objetivo deste texto é discutir a dinâmica relacional que envolve o afrocentramento, abrindo a abordagem à diferença. São apresentados pressupostos teóricos nos campos do currículo e das relações étnico-raciais. Currículo é tratado como política cultural. Já relações étnico-raciais, como conjunto ativo de respostas em relação a questões em debate que guiam as demandas em disputa. O caso da cultura afro-ameríndio-maranhense – no contexto da amefricanidade – e seus rastros autobiográficos são mobilizados de modo a ilustrar e a compor o quadro argumentativo em defesa da diferença como abertura, fluxo de sentidos. Sem a pretensão de esgotamento, este trabalho salienta que o caráter de afrocentramento vem se constituindo como tática diante dos históricos ataques eurocêntricos. No entanto, há risco – quando predomina o apagamento do caráter aberto dos processos de identificação e singularidades – de que não se possa dar conta do que a experiência afro-maranhense e a autobiografia apontam como exemplos da dimensão relacional e da impossibilidade de sutura. A diferença remete à imprevisibilidade e ao acontecimento, inevitáveis ao novo, diante de sedimentações.
Carolina vai às escolas: produzindo currículo antirracista no interior da Bahia
Authors: Santos Cleber Lúcio Sousa , Moreira Núbia Regina , Gomes Talita
Published: June 2024

Este artigo objetiva apresentar uma análise de atividades produzidas por um grupo de pesquisa formado por professoras/es pesquisadoras/es, estudantes licenciados e bacharéis, em sua maioria mulheres negras imbuídas/os na des/re/construção dos currículos eurocentrados. Trata-se de ações construídas mediante teares de teorias e práticas curriculares insurgentes e decoloniais, irrigadas pelas epistemologias feministas negras. O campo empírico foi produzido por meio de rodas de conversa em escolas estaduais de ensino médio, situadas em três municípios baianos, que tiveram como disparador o Projeto Carolina Vai às Escolas. O Projeto visou a apresentar os dilemas da realidade brasileira perante duas obras de Carolina Maria de Jesus: Quarto de Despejo: Diário de uma Favelada (2019) e Diário de Bitita (2014). As cartas produzidas pelas/pelos estudantes das turmas que tiveram envolvidas/os no projeto trazem a complexidades dos dilemas postos por Carolina, que, assim como a autora, têm suas vidas atravessadas pelo racismo, machismo e dificuldades financeiras. Com Carolina, elas/eles são afetados com a força vital que a movimentou em direção ao seu sonho de escrever, mensagem que reverberou nos estudantes a possibilidade de imaginar a melhoria das suas vidas por meio da educação.
FAKTOR YANG BERHUBUNGAN DENGAN STATUS GIZI PENYANDANG AUTISM SPECTRUM DISORDER (ASD) DI SEKOLAH KHUSUS WILAYAH JABODETABEK TAHUN 2023
Authors: Ramadhanty Citra , Simanungkalit Sintha Fransiske , Octaria Yessi Crosita , Maryusman Taufik
Published: June 2024

Latar Belakang: Prevalensi penyandang Autism Spectrum Disorder (ASD) di Indonesia diprediksi bertambah 500 orang per tahunnya dan masih banyak ditemukan masalah status gizi pada kelompok anak dengan ASD.
Tujuan: Menganalisis hubungan tingkat pendidikan ibu, pola asuh, pengetahuan gizi seimbang, dan pendapatan orang tua terhadap status gizi penyandang Autism Spectrum Disorder (ASD) di Sekolah Khusus wilayah JABODETABEK.
Metode: Penelitian ini merupakan penelitian observasional dengan desain cross-sectional. Populasi pada penelitian ini yaitu penyandang Autism Spectrum Disorder (ASD) di Sekolah Khusus wilayah JABODETABEK. Pengambilan sampel dilakukan menggunakan metode Quota Sampling, penelitian dilakukan pada bulan Maret-Mei dengan jumlah sampel sebanyak 114 responden. Analisis data yang digunakan adalah uji Spearman Rank.
Hasil: Hasil penelitian menunjukkan bahwa rata-rata penyandang ASD memiliki status gizi baik (0,81). Uji bivariat menunjukkan terdapat hubungan antara pola asuh (p= 0,007; r=0,250) dengan status gizi penyandang ASD, yang berarti bahwa variabel ini memiliki korelasi positif yang cukup kuat dengan status gizi. Namun, tidak terdapat hubungan antara tingkat pendidikan ibu (p=0,949), pengetahuan gizi seimbang (p=0,728) dan pendapatan orang tua (0,976) dengan status gizi penyandang ASD.
Kesimpulan: Pola asuh menunjukkan korelasi positif yang signifikan dengan status gizi pada penyandang Autism Spectrum Disorder (ASD) di Sekolah Khusus wilayah JABODETABEK.
Pemberian Serbuk Daun Kelor (Moringa oleifera) terhadap Perbaikan Profil Lipid dan Ketebalan Aorta pada Tikus Model Prediabetes Mellitus
Authors: Ariestiningsih Ayuningtyas Dian , Cempaka Anggun Rindang , Kusumastuty Inggita , Cahyaningrum Aladhiana , Setiawati Sindi , Arintya Diandra , Azmi Ulul , Salwa Putri , Malahayati Huzaifah , Wibowo Rizka Azhari , Handayani Dian
Published: June 2024

Latar Belakang: Konsumsi makanan dan minuman kemasan dengan kandungan tinggi fruktosa mengalami peningkatan beberapa tahun terakhir. Hal ini meningkatkan risiko terjadinya sindrom metabolik, meliputi resistensi insulin, peningkatan tekanan darah, dan gangguan profil lipid. Daun kelor (Moringa oleifera) dengan kandungan senyawa bioaktif yang berfungsi sebagai antioksidan diketahui mampu memperbaiki metabolisme lemak dan glukosa darah.                                                                                            
Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh serbuk daun kelor (Moringa oleifera) dalam mengontrol kondisi sindrom metabolik melalui identifikasi profil lipid dan ketebalan aorta pada prediabetes mellitus.
Metode: Penelitian ini merupakan studi eksperimental dengan pendekatan post test only control group design. Sebanyak 35 ekor tikus putih (Rattus novergicus) galur Wistar jantan dibagi menjadi 5 kelompok yaitu kelompok K0 (pakan standar), E1 (sonde fruktosa 66% selama 16 minggu), E2 (sonde fruktosa 66% selama 12 minggu), E3 (sonde fruktosa 66%+kuersetin 50 mg/kg BB), dan E4 (sonde fruktosa 66%+serbuk daun kelor 500 mg/kg BB). Data dianalisis menggunakan uji One Way ANOVA.
Hasil penelitian: Kadar kolesterol total, HDL kolesterol, dan ketebalan dinding aorta berbeda signifikan antarkelompok perlakuan. Tidak terdapat perbedaan yang signifikan pada kadar trigliserida, LDL kolesterol, dan massa jaringan lemak putih antar kelompok perlakuan.
Kesimpulan: Pemberian serbuk daun kelor selama 4 minggu menunjukkan perbaikan profil lipid dan ketebalan dinding aorta pada kondisi prediabetes mellitus.
Tinjauan Literatur: Hubungan Obesitas dan Infertilitas pada Pria Usia Produktif
Authors: Putri Allisa Nadhira Permata Arinda , Nadhiroh Siti Rahayu
Published: June 2024

Latar Belakang: Obesitas merupakan masalah epidemi dunia yang mengalami kenaikan secara terus menerus. Obesitas berpengaruh negatif pada beberapa fungsi dalam tubuh yaitu termasuk fungsi reproduksi (fertilitas). Prevalensi pasangan infertil di Indonesia pada tahun 2013 sebesar 15-25% dengan infertilitas pada pria menyumbang 25-30% dari total kasus infertilitas.
Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara obesitas dan infertilitas pada pria usia produktif.
Metode: Studi penelitian ini menggunakan metode literature review bersumber dari hasil penelitian berdasarkan kriteria inklusi berupa literatur berkredibel baik dengan topik obesitas dan infertilitas pria sebanyak 8 penelitian observasional. Referensi yang tidak dapat diakses secara full text dan penelitian pada hewan uji coba termasuk dalam kriteria ekskusi penelitian.
Ulasan: Obesitas dapat mempengaruhi kesuburan pria secara langsung atau tidak langsung melalui beberapa mekanisme perubahan profil hormonal. Obesitas dapat menyebabkan adanya perubahan androgen menjadi estrogen secara berlebihan sehingga dapat meningkatkan aktivitas aromatase dan reproduksi selanjutnya sehingga ketidakseimbangan ini dapat menurunkan kualitas dari sperma. Pada keadaan obesitas sendiri menyebabkan kadar leptin plasma yang tinggi. Peningkatan stres oksidatif yang diinduksi leptin dan produksi reactive oxygen species (ROS) yang tidak terkendali sehingga berdampak negatif pada fluiditas membran plasma sperma, merusak motilitas sperma, dan meningkatkan kerusakan DNA (deoxyribonuclealic acid) sperma.
Kesimpulan: Peningkatan body mass index (BMI)  meningkatkan risiko kejadian penurunan parameter sperma yang mengacu pada peningkatan derajat infertilitas pada pria. Pria obesitas dapat meningkatkan risiko perubahan parameter sperma secara kuantitatif (volume, jumlah, dan konsetrasi) serta kualitatif (motilitas, morfologi, dan DNA sperma).
Pengaruh Nutritional Support terhadap Luaran Klinis pada Pasien Intensive Care Unit
Authors: Harti Leny Budhi , Dini Cleonara Yanuar , Fatoni Arie Zainul
Published: June 2024

Latar Belakang: Dukungan gizi (nutritional support) pada pasien kritis merupakan standar perawatan yang diakui secara internasional dan bagian yang terintegrasi dari terapi klinik pada pasien Intensive Care Unit (ICU) yang bertujuan untuk memperbaiki luaran klinis pasien.
Tujuan: Penelitian ini adalah untuk menginvestigasi pengaruh pemberian nutritional support dalam bentuk nutrisi enteral terhadap luaran klinis pada pasien ICU.
Metode: Desain penelitian ini adalah sistematik review dari beberapa artikel penelitian dengan desain penelitian Randomized Controlled Trial (RCT) sejak tahun 2010 hingga 2020. Penulisan sistematik review ini mengacu pada ketentuan PRISMA. Luaran klinis yang diteliti meliputi: lama rawat inap di Rumah Sakit (RS), lama rawat inap di ICU, dan mortalitas.
Ulasan: Penelitian menunjukkan dari 897 artikel terdapat 6 artikel yang relavan. Responden penelitian merupakan pasien rawat inap di ICU yang mendapatkan formula enteral, baik responden pada kelompok kontrol maupun kelompok intervensi. Pada kelompok intervensi pasien mendapatkan formula enteral dengan modifikasi energi (normokalori dan tinggi protein) dan zat gizi (diperkaya dengan pektin dan immunonutrient). Dukungan gizi berupa nutrisi enteral memberikan efek yang bervariasi terhadap lama rawat inap di RS, ICU, dan mortalitas.
Kesimpulan: Lama rawat inap di ICU dan RS antara pasien yang mendapatkan nutrisi enteral standar/hipokalori/tinggi protein tidak berbeda bermakna dengan pasien yang mendapatkan nutrisi enteral yang diperkaya dengan pektin atau immunonutrient. Namun demikian, pasien yang mendapatkan nutrisi enteral dengan immunonutrient memiliki lama rawat inap yang lebih rendah. Hal yang perlu diperhatikan dari penelitian ini adalah pemberian immunonutrient dapat meningkatkan risiko mortalitas 60 hari dan 28 hari pada pasien kritis.
Indonesia Merger Control Re-Evaluation : Twenty Years’ Experience In Legal Limbo
Authors: Setyawati Ria , Iman Prihandono  , Kagramanto Lucianus Budi , Stefan Koos
Published: June 2024

This paper not only discusses the issue of the approach used, the issue of ex-post and ex-ante merger control regulation usage, issues of conflict of norms, overlapping legal rules, and the existence of legal vacuum which complicates the enforcement of rules regarding merger control in Indonesia. The legal issues examined in this paper concern the characteristics of merger control based on the ratio decidendi of KPPU decisions during the 20 years of enforcing business competition law in Indonesia and the ius constituendum of the ex-ante and ex-post approach. This research is based on normative legal research using a statute approach, conceptual approach, case approach, and comparative approach method. These methods lead to the conclusion of the research, which is, that in the past 20 years, Indonesia has experienced a change in the ex-post merger control approach, resulting in partiality in the articles applied that are not entirely used in KPPU decisions. Furthermore, the idealized rules (ius constituendum) on the control of mergers in Indonesia, outlined in Law No. 5 of 1999, will be examined based on the principles and objectives of competition law enforcement in the country.
Observance of the Legal Choice for the Settlement of Indonesia's Past Gross Violations of Human Rights
Authors: Subawa I Made , Hermanto Bagus , Mas Ratu Ida Ayu , Mariko Hattori
Published: June 2024

Global developments attempt to rectify serious human rights breaches within the context of legal regulations, as well as to build human rights systems and institutions on a national and global scale. However, in Indonesia, the paradigm shift from authoritarianism to democracy leads human rights as one of most important issues faced by the Indonesia government. In the last two decades, the red record in resolving major human rights abuses has not been attained, necessitating a study to evaluate effective legal choices in settlement of the past human rights violations settlement. This paper employed a statutory method, legal concepts, legal cases, and citations. The comparison validates the direction of this paper's research on the dynamics of national legal concerns in the policy of resolving gross human rights abuses and the selection of law that may be employed in effectively resolving major human rights violations in favor of transitional justice. The obtained results and findings show that problems have emerged in policy orientation at the macro, mezzo, and micro policy strata, as well as the need for future direction in the substance of legislation and the enforcement system, both through judicial and extrajudicial channels, against serious human rights violations.
Legal and Moral Principles as Guidelines for Carrying Out Official Duties
Authors: Saputro Aries , Radian Salman
Published: June 2024

Law and morals are related as an ideal value in the formation of law, because morals are considered universal values ​​that should ideally characterize every legal formation, with the hope that morality in the law can produce good behavior for legal subjects and objects. These morals and laws are in our administrative law, in this case the executive. The problem that is difficult to solve is the problem of corruption, where the act is legally and morally not good or wrong. Anti-corruption regulations are in place and the establishment of the Corruption Eradication Commission reveals that the problem of corruption in our country is not resolved and is even more systematic. Ideally, with the advancement of civilization and the strengthening of moral values ​​as the basis for rules, corruption will decrease to its lowest point from year to year as a government develops. Then, if this law represents a moral value, then the court decision, which is the law, can also contain moral values. As an example also regarding court decisions by state administration officials that are not implemented voluntarily, this can be equated with blatant disobedience to the law making state administration officials arrogant.   Normative juridical analysis used in research includes legal and regulatory theory. Therefore, in order to achieve conformity regarding the morals and behavior of state officials in carrying out their duties, there is a close connection between the bad morals of state officials and behavior that violates the law. The good morals of state officials will make the behavior of state officials high and far from breaking the law.
'Regulaciones para la descarga de aguas residuales de México: comparacion con otros países y su cumplimiento en plantas de tratamiento seleccionadas
Authors: Domínguez-Montero Lilian Edith , Poggi-Varaldo Héctor Mario , Cañizares-Villanueva Rosa Olivia , Padilla Viveros América Alejandra , Rinderknecht-Seijas Noemi , Caffarel-Méndez Sergio , de la Cruz-Burelo Eduard
Published: June 2024

El propósito de este estudio fue: i) describir y comparar las normas oficiales mexicanas de descarga de aguas residuales 1996 y 2021 (norma antigua, NA y norma nueva NN, respectivamente); ii) comparar las dos normas oficiales mexicanas para la descarga de aguas residuales con las regulaciones de Brasil, Estados Unidos, Canadá y la Unión Europea (UE); así como determinar el índice de permisividad de los contaminantes básicos y del subconjunto de los metales pesados y los cianuros, también llamados “otros contaminantes”; y iii) analizar el cumplimiento de las NN y NA mexicanas con una muestra de resultados analíticos de los efluentes de 25 plantas de tratamiento de aguas residuales municipales que operan en un área metropolitana de México. Los resultados de esta investigación sugieren que la nueva NOM 2021 es muy cercana a la norma previa 1996 en términos de permisividad, y a su vez ambas son muchísimo más permisivas comparadas con las de los países desarrollados del Tratado entre México, Estados Unidos y Canadá (T-MEC) y de la UE. Los altos límites máximos permisibles de la mayoría de los contaminantes en ambas normas mexicanas podrían causar impactos negativos en los cuerpos de agua y en los bienes nacionales. Se recomienda la actualización y expansión de las NOM-002 y 003, y eventualmente la revisión de la propia NOM-001-2021 para eliminar o reducir el riesgo para la salud y el ambiente de los contaminantes del agua y homologar la calidad del recurso agua en el contexto de los países integrantes del T-MEC.
Perception and Barriers to Improved Charcoal Cookstove Adoption in Wereta, Ethiopia
Authors: Ashagrie Tessafa Abrham , Geremew Shumet , Misganaw Wondimhunegne , Shiferie Adamu , Dires Tadese , Maru Getu
Published: June 2024

The global energy crisis is a significant issue, particularly in developing countries like Ethiopia, where traditional fuels such as wood and charcoal are predominantly used to meet energy demands in urban and rural areas. Despite Ethiopia's substantial charcoal production, the use of inefficient charcoal cookstoves exacerbates fuel consumption, forest degradation, and environmental damage. To address this, various improved charcoal cookstoves (ICS) have been introduced in urban and semi-urban communities in Wereta Town, located in the Amhara Regional State of Ethiopia. This study aims to evaluate household perceptions and identify barriers to the adoption of ICS in the Wereta district. The assessment involved a survey of 308 households using a structured cross-sectional method and analyzed five types of improved cookstoves: clay stoves, insulated clay cylinder stoves, non-insulated rocket stoves, insulated rocket stoves, and non-insulated cylindrical stoves. The study employed various socio-economic variables and utilized both cross-tabulation frequency factors and linear regression statistical analysis through SPSS 20 to identify factors influencing the adoption of ICS. The linear regression results indicated that marital status, income level, family size, and age significantly impact ICS adoption (p-value < 0.05), while the place of cooking, educational level, household decision-making, and the role of societal stakeholders showed no significant impact. This suggests that ICS adoption is primarily influenced by household income levels and family size.
An Ethnographic Exploration of Cross-Cultural Challenges in Global Supply Chains
Authors: Reynolds Samantha
Published: June 2024

This ethnographic study investigates the cross-cultural challenges encountered in global supply chains, focusing on communication barriers, diverse business practices, trust-building, ethical and legal standards, and cultural competence. By embedding within the day-to-day operations of multinational corporations and conducting in-depth interviews with supply chain professionals, the research provides a nuanced understanding of the cultural dynamics that impact global supply chain management. The findings highlight that effective communication goes beyond language proficiency, requiring an understanding of varying communication styles and contextual nuances. Business practices shaped by cultural values such as power distance and uncertainty avoidance necessitate adaptive management strategies that balance local norms with global standards. Trust and relationship-building are critical, particularly in cultures where personal relationships underpin business transactions, demanding long-term investment in relationship-building activities. Ethical and legal standards vary significantly across regions, presenting challenges that require a nuanced approach to global governance. The study underscores the importance of cultural competence as a critical skill for supply chain professionals, enabling them to bridge cultural gaps and foster productive collaborations. Sustainability efforts, entrepreneurship, and innovation are also influenced by cultural factors, highlighting the need for culturally sensitive strategies. Emotional intelligence is identified as essential for managing cross-cultural interactions, with participants demonstrating high emotional intelligence more effectively navigating the emotional and social complexities of cross-cultural communication. The use of technology in managing cross-cultural challenges is acknowledged, but the findings suggest that it must be complemented by cultural competence. Overall, the study provides valuable insights for companies seeking to enhance their cross-cultural effectiveness, emphasizing the importance of cultural competence, communication, and relationship-building in achieving sustainable success in global supply chains.
Experimental Study of the Swelling and Rheological Properties of a High-Strength Preformed Particle Gel Lost Circulation Material
Authors: Zhu Yuecheng , Bai Yingrui , Sun Jinsheng , Lv Kaihe
Published: June 2024

Preformed particulate gel (PPG) has emerged as a widely utilized lost circulation material in deep oil and gas drilling operations. The objective of our study was to devise a high-strength preformed particle gel (HSPPG) specifically designed to address drilling fluid loss in high-temperature fractured formations. To achieve this, a comprehensive set of laboratory experiments was conducted to assess the swelling and rheological properties of HSPPG under various conditions, and these investigations aimed to provide deeper insights into the pressure-bearing mechanism exhibited by HSPPG. The synthesis of HSPPG involved the copolymerization of acrylamide (AM) and N-hydroxymethacrylamide (NMA) molecular chains, catalyzed by organic peroxides, to form the primary network. Additionally, to enhance its temperature resistance, urea-formaldehyde (UF) resin, known for its superior thermal stability, was incorporated into the secondary network. This unique combination of primary and secondary networks imparted remarkable thermal endurance and structural stability to the resulting HSPPG. The swelling and rheological experiments revealed that HSPPG, with a particle size of 1000 µm, exhibited an equilibrium swelling rate (SR) value of 30.55 and a storage modulus (G’) of 1050 Pa at 120℃. These findings attested to its excellent temperature resistance and structural stability. Furthermore, when subjected to a sodium chloride solution at a temperature of 120℃ and a concentration of 25.0%, HSPPG achieved equilibrium swelling with an SR value of 24.93 and a G’ of approximately 7000 Pa. This significant increase in structural strength was attributed to charge shielding within the highly concentrated brine environment. In the plugging experiments, a wedge-shaped slit with an inlet of 3 mm and an outlet of 1 mm was successfully blocked using a concentration of 4% of HSPPG with a particle size of 1000 μm. The blocking strength achieved was 8.06 MPa. The results of these experiments, as well as the observed filling and plugging state of HSPPG in steel fractured cores, indicated that HSPPG possesses the properties of water absorption, swelling, and extrusion filling. These attributes facilitate the effective formation of a dense blocking layer within the fracture space, exhibiting excellent pressure-bearing capacity. In conclusion, the HSPPG developed in this study represents an advanced swellable granular plugging agent with excellent swelling capacity and structural strength at high temperatures. It offers an ideal solution to mitigate drilling fluid loss from fractured formations under high-temperature and high-salinity conditions.
Potential of Heterorhabditis bacteriophora JAAN-19 for sustainable management for prickly pear cactus weevil Metamasisus (Syn. Cactophagus) spinolae
Authors: Chávez-Díaz Ismael Fernando , Sáenz-Aponte Adriana , Pérez-Ricardo Vicente , Cortez-Madrigal Hipolito , Andrade-Hoyos Petra , Hernández-Dominguez Carmela , Aragón-Magadan Marco Aurelio , Grifaldo-Alcántara Pedro Fabián
Published: June 2024

The prickly pear cactus, is a crop of cultural, gastronomic, and economic significance in Mexico due to its diverse uses. One of the major challenges to its yield is the cactus weevil. While agrochemicals have been the primary method of control, various alternatives have been explored for sustainable agriculture using traps, parasitoids and entomopathogenic fungi with differential mortality between male and female pests, with some reaching a maximum effectiveness of 70-80%. This study explored the potential of the nematode identified as Heterorabditis bacteriophora JAAN-19 as a biocontrol agent. In vitro, a concentration of 1000 Jl/weevil achieved 90% mortality in females and males after six days. Notably, the substrate experiments, mimicking real-world conditions, demonstrated the nematode's strong searching and infective capacity, reaching 97% mortality at the same concentration within 6-8 days. Experiments revealed that the nematode's effectiveness depended on dose and exposure time, not the weevils' sex. Based on the experiment observations, the lethal dose (LD50) for the weevils was 138 Jl/weevil, and the dose for 90% mortality (LD90) was 463 Jl/weevil, both within a 6-8 day period. These findings support the high agrobiotechnological potential of H. bacteriophora JAAN-19 as a sustainable control strategy against the cactus weevil Metamasius spinolae.
TrkB-dependent antidepressants action involves Dlx5/6 inhibition in cortical GABAergic neurons.
Authors: Narboux-Nême Nicolas , Aouci Rym , Fontaine Anastasia , Vion Amin , Levi Giovanni , Belz Lou
Published: June 2024

Major depressive disorder (MDD) is a complex and devastating illness that affects people of all ages. However, both the aetiology of MDD and the mechanisms of action of antidepressants are not completely understood. Many indications suggest the involvement of Parvalbumin-positive GABAergic neurons (PV-neurons) in the pathogenesis of MDD. DLX5 and DLX6 (DLX5/6) encode for two homeodomain transcription factors involved in cortical GABAergic differentiation and function. In the mouse, the level of expression of these genes is inversely correlated to the cortical density of PV-neurons and to anxiety-like behaviours. The same genomic region generates the lncRNA DLX6-AS1 which, in humans, has been identified as the most central hub gene in the interneuron module downregulated in schizophrenia and ASD. PV-neurons are complex inhibitory interneurons affected in many neuro-psychiatric conditions including MDD and schizophrenia. Here, we show that the expression levels of Dlx5/6 in the adult mouse brain are inversely correlated with immobility time in the forced swimming test, an assay used to study of depressive-like behaviours and the efficacy of anti-depressive drugs in rodents. We show that the administration of the antidepressant Fluoxetine (Flx) to normal mice induces, within 24h, a rapid and stable reduction of Dlx5, Dlx6 and Dlx6-AS1 expression in the cerebral cortex through the activation of the TrkB-CREB cascade and can counteract the behavioural and cellular alterations induced by experimental Dlx5 overexpression. Our findings show that one of the short-term effects of Flx treatment is the reduction of Dlx5/6 expression in GABAergic neurons, which, in turn has direct consequences on PV expression and on behavioural profiles. Variants in the DLX5/6 regulatory network could be implicated in the predisposition to depression and in the variability of patients’ response to treatment and can constitute a target for further understanding the mechanism of action of antidepressants.
Association between Antenatal Corticosteroids and Neonatal Outcomes among Very Preterm Infants Born to Mothers with Hypertensive Disorders of Pregnancy: A Multicenter Cohort Study
Authors: Sun Mengya , Qian Aimin , Li Xianghong , Bai Ruimiao , Cheng Ping , Gu Xinyue , Wang Yanchen , Cao Yun , Zhou Wenhao , Lee Shoo K. , Jiang Hong , Jiang Siyuan
Published: June 2024

Background
The relationship between antenatal corticosteroids (ACS) and preterm infants born to mothers with hypertensive disorders of pregnancy (HDP) remains a subject of debate. To evaluate whether the use of ACS before delivery was associated with neonatal outcomes in very preterm infants born to mothers with HDP.
Methods
This multicenter cohort study enrolled all infants with gestational age at 24 to 31 week and admitted to tertiary NICUs of the Chinese Neonatal Network (CHNN) within 24 hours of birth from 2019 to 2021. ACS administration was defined as at least one dose of dexamethasone or betamethasone before delivery. The primary outcome was surfactant and/ or invasive mechanical ventilation (IMV) within 72 hours of life. Multivariable logistic regression analyses were performed to assess the association between ACS and neonatal outcomes.
Results
Among the 4,582 study infants born to mothers with HDP, 3,806 (83.1%) were exposed to ACS. ACS treatment was significantly associated with lower risk of requirement of surfactant and/ or IMV within 72 hours of life (adjusted Odds Ratio = 0.60, 95% confidence interval 0.49–0.74). ACS exposure was also independently associated with decreased mortality, surfactant use, IMV, combined surfactant and IMV use and moderate or severe bronchopulmonary dysplasia. The severity of maternal HDP did not appear to influence the correlation between ACS treatment and neonatal outcomes. Our analysis also indicated that a single complete course seemed to have the most significant protective effect.
Conclusions
Our study reinforces the significant role of ACS in reducing severe respiratory morbidity and mortality in very preterm infants born to mothers with HDP.