bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Synthesis and Reactions of Some New Benzopyranone Derivatives with Potential Biological Activities.
Authors: El‐Desoky El‐Sayed I. , Al‐Shihry Shar S.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solvent‐Free One‐Pot Approach for Synthesis of Substituted 2‐Aminochromenes.
Authors: Zhou Dong , Ren Zhongjiao , Cao Weiguo , Chen Jie , Deng Hongmei
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: β‐Oxoanilides in Heterocyclic Synthesis: An Expeditious Synthesis of New Polyfunctionally Substituted Pyridine and Pyrazole Derivatives.
Authors: Husein A. M. , Harb A. A. , Mousa I. A.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sustainable Synthetic Methods: Domino Construction of Dihydropyridin‐4‐ones and β‐Amino Esters in Aqueous Ethanol.
Authors: Alaimo Peter J. , et al. et al.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ionic Liquid — An Efficient Recyclable System for the Synthesis of 2,4‐Disubstituted Quinolines via Meyer—Schuster Rearrangement.
Authors: Sarma Rupam , Prajapati Dipak
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New 1,10‐Phenanthroline Derivatives with Potential Antitumoral Activity.
Authors: Dumitrascu Florea , Caira Mino R. , Draghici Constantin , Caproiu Miron T. , Barbu Loredana , Miu Barbu
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Annulated 2H‐Indazoles and 1,2,3‐ and 1,2,4‐Triazoles via a One‐Pot Palladium‐Catalyzed Alkylation/Direct Arylation Reaction.
Authors: Laleu Benoit , Lautens Mark
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multicomponent Reactions of Pyridines, α‐Bromo Carbonyl Compounds and Silylaryl Triflates as Aryne Precursors: A Facile One‐Pot Synthesis of Pyrido[2,1‐a]isoindoles.
Authors: Huang Xian , Zhang Tiexin
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polystyrene‐Supported AlCl3: A Highly Active and Reusable Heterogeneous Catalyst for the One‐Pot Synthesis of Dihydropyrimidinones.
Authors: Wang Liang , Cai Chun
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: First Example of the Groebke MCR Using Hydroxybenzaldehydes and Substituted 2‐Aminopyrimidines.
Authors: Polyakov Anatoliy I. , Eryomina Vera A. , Medvedeva Lidiya A. , Tihonova Nadezhda I. , Voskressensky Leonid G.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solvent‐Free Synthesis of 5‐Methyl‐7‐aryl‐4,7‐dihydrotetrazolo[1,5‐a]pyrimidine‐6‐carboxylic Esters Catalyzed by Sulfamic Acid.
Authors: Yao Changsheng , Lei Song , Wang Chuihua , Yu Chenxia , Tu Shujiang
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organic Azides in Heterocyclic Synthesis. Part 35. Ring Closure Reactions of 5‐Azidopyrido[2,3‐d]pyrimidinetriones to Isoxazolo‐ and Oxadiazolopyrido[2,3‐d]pyrimidinetriones.
Authors: Tinh Dang Van , Stadlbauer Wolfgang
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Novel Pyrazolo[3,4‐d]pyridazine (VI), Pyrido[1,2‐a]benzimidazole (X), Pyrimido[1,2‐a]benzimidazole (XII) and Triazolo[4,3‐a]pyrimidine Derivatives (XIV).
Authors: Shaaban Mohamed R. , Eldebss Taha M. A. , Darweesh Ahmed F. , Farag Ahmad M.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of New Pyrido[4′,3′:4,5]thieno[2,3‐d]pyrimidin‐4(3H)‐one Derivatives.
Authors: Zeng Guo‐Ping , Hu Yang‐Gen , Ding Ming‐Wu
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Convenient Synthesis of 2,4‐Disubstituted‐1,2,4‐triazolo[1,5‐a]quinazolin‐5(4H)‐ones.
Authors: Shawali Ahmad S. , Hassaneen Hamdi M. , Shurrab Nabil Kh.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tertiary Amine Effect: Synthesis of Some Novel Spirosubstituted Pyrido[2,3‐d]pyrimidines.
Authors: Baruah Biswajita , Bhuyan Pulak J.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Mild and Highly Efficient Method for the Synthesis of 5‐Aryl‐(N‐phenyl‐)6H‐1,3,4‐thiadiazin‐2‐aminium Salts Using Reusable Heterogeneous Catalysts.
Authors: Rostamizadeh Shahnaz , Shadjou Nasrin , Amani Ali M. , Aryan Reza
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Recyclable Catalyst for the Synthesis of 1,5‐Benzodiazepine Derivatives: Polymer‐Supported Ytterbium Perfluorooctanesulfonate [Yb(OPf)3].
Authors: Tao Feng , Yi Wen‐Bin
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sequential Aza‐Claisen Rearrangement and Ring‐Closing Metathesis as a Route to 1‐Benzazepine Derivatives.
Authors: Ghosh Debalina , Thander Latibuddin , Ghosh Sanjay K. , Chattopadhyay Shital K.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of New 2‐Amino‐ (VI) and 2,3‐Diamino‐pyridine Trifluoroacetyl Enamine Derivatives (III) and Their Application to the Synthesis of Trifluoromethyl‐Containing 3H‐Pyrido[2,3‐b][1,4]diazepinols (IV).
Authors: Bonacorso Helio G. , Lourega Rogerio V. , Righi Fernando J. , Deon Everton D. , Zanatta Nilo , Martins Marcos A. P.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbocupration—Functionalization of Arynes: Rapid Access to Variably ortho‐Substituted ((E)‐3‐Phenylprop‐1‐enyl)silanes.
Authors: Ganta Ashok , Snowden Timothy S.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selective Mono‐ and Diallylation and Allenylation of Chlorosilanes Using Indium.
Authors: Li Zhifang , Yang Chenjun , Zheng Hongfang , Qiu Huayu , Lai Guoqiao
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Darzens Reaction of Acyl Phosphonates with α‐Bromo Ketones: Selective Synthesis of cis‐ and trans‐Epoxyphosphonates.
Authors: Demir Ayhan S. , Emrullahoglu Mustafa , Pirkin Eser , Akca Nazmiye
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Route to 4‐Halophosphaisocoumarins via CuX2‐Mediated Direct Halocyclization of 2‐(1‐Alkynyl)phenylphosphonic Acid Diesters.
Authors: Peng Ai‐Yun , Hao Fei , Li Baojian , Wang Zheng , Du Yidan
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,3,2‐(2H)‐Dioxaborine Polymethine Dyes on the Base of Dehydroacetic Acid — Effective Fluorescent Amine Probes.
Authors: Gerasov Andriy O. , Shandura Mykola P. , Kovtun Yuriy P. , Vlasenko Yuriy G. , Gorchev Vasyliy F.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Triterpenoids from the Leaves of Photinia serrulata.
Authors: Yang Li‐Bing , Zhao Li‐Xing
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile Synthesis of N‐α‐Boc‐1,2‐Dialkyl‐L‐histidines (VI): Utility in the Synthesis of Thyrotropin‐Releasing Hormone (TRH) Analogues (VII) and Evaluation of the CNS Activity.
Authors: Monga Vikramdeep , Meena Chhuttan Lal , Kaur Navneet , Kumar Satyendra , Pawar Chandrashekhar , Sharma Shyam Sunder , Jain Rahul
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Chiral Carbohydrate Ionic Liquids.
Authors: Plaza Patrice G. J. , Bhongade Bhoomendra A. , Singh Gurdial
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of Rare Sugar D‐Allal via Reversal of Diastereoselection in the Reduction of Protected 1,5‐Anhydrohex‐1‐en‐3‐uloses: Protecting Group Dependence of the Stereoselection.
Authors: Fujiwara Takashi , Hayashi Masahiko
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly β‐Selective C‐Allylation of a Ribofuranoside Controlling Steric Hindrance in the Transition State.
Authors: Ichikawa Satoshi , Hayashi Ryoko , Hirano Shinpei , Matsuda Akira
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient O‐Glycosylations with p‐Tolyl Thioribosides and p‐TolSOTf.
Authors: Kurosu Michio , Li Kai
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.
Authors: Awang Khalijah , Ahmad Kartini , Thomas Noel F. , Hirasawa Yusuke , Takeya Koichi , Mukhtar Mat Ropi , Mohamad Khalit , Morita Hiroshi
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phomoeuphorbins A—D, Azaphilones from the Fungus Phomopsis euphorbiae.
Authors: Yu Bu‐Zhu , Zhang Gao‐Hong , Du Zhi‐Zhi , Zheng Yong‐Tang , Xu Jian‐Chu , Luo Xiao‐Dong
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Cyclopropyl Diketones and 14‐Membered Macrolides from the Soil Fungus Hamigera avellanea BCC 17816.
Authors: Isaka Masahiko , Chinthanom Panida , Veeranondha Sukitaya , Supothina Sumalee , Luangsa‐ard J. Jennifer
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Spirotenuipesines A (I) and B (II).
Authors: Dai Mingji , Krauss Isaac J. , Danishefsky Samuel J.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Clustering and Classifying Diverse HIV Entry Inhibitors Using a Novel Consensus Shape‐Based Virtual Screening Approach: Further Evidence for Multiple Binding Sites within the CCR5 Extracellular Pocket.
Authors: Perez‐Nueno Violeta I. , Ritchie David W. , Borrell Jose I. , Teixido Jordi
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Targets Looking for Drugs: A Multistep Computational Protocol for the Development of Structure‐Based Pharmacophores and Their Applications for Hit Discovery.
Authors: Tintori Cristina , Corradi Valentina , Magnani Matteo , Manetti Fabrizio , Botta Maurizio
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Virtual Screening for R‐Groups, Including Predicted pIC50 Contributions, within Large Structural Databases, Using Topomer CoMFA.
Authors: Cramer Richard D. , Cruz Phillip , Stahl Gunther , Curtiss William C. , Campbell Brian , Masek Brian B. , Soltanshahi Farhad
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 3D QSAR/CoMFA and CoMSIA Studies on Antileukemic Steroidal Esters Coupled with Conformationally Flexible Nitrogen Mustards.
Authors: Kapou Agnes , Benetis Nikolas‐P. , Durdagi Serdar , Nikolaropoulos Sotiris , Mavromoustakos Thomas
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Comparative Study of Topological Indices of Macro/Supramolecular RNA Complex Networks.
Authors: Agueero‐Chapin Guillermin , Antunes Agostinho , Ubeira Florencio M. , Chou Kuo‐Chen , Gonzalez‐Diaz Humberto
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Interaction Model Based on Local Protein Substructures Generalizes to the Entire Structural Enzyme‐Ligand Space.
Authors: Stroembergsson Helena , Daniluk Pawel , Kryshtafovych Andriy , Fidelis Krzysztof , Wikberg Jarl E. S. , Kleywegt Gerard J. , Hvidsten Torgeir R.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Synthesis and Optical Properties of Large‐Scale GaN Nanorods.
Authors: Chen Jinhua , Xue Chengshan , Zhuang Huizhao , Yang Zhaozhu , Qin Lixia , Li Hong , Huang Yinglong
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Carbon‐Nanotube Composites Using Supercritical Fluids and Their Potential Applications
Authors: Liu Zhimin , Han Buxing
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrochemical Membrane Technique for Studying Hydrogen Transport in Germanium
Authors: Konorov P. P. , Rodionov N. V. , Yafyasov A. M. , Bozhevol'nov V. B.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nanoparticulate Porous Films for Electrochemical Device Applications
Authors: Fujihara Shinobu , Kakiuchi Keita , Hosono Eiji
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lu—S (Lutetium—Sulfur)
Authors: Okamoto H.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Environmental Catalysis: A Push to the Development of New Catalytic Materials
Authors: Centi Gabriele , Perathoner Siglinda
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Artificial Enzyme Catalysis Controlled and Driven by Light.
Authors: Knoer Guenter
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metal‐Catalyzed One‐Step Synthesis: Towards Direct Alternative to Multistep Heterocycle and Amino Acid Derivative Formation.
Authors: Arndtsen Bruce A.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Applications of Multicomponent Reactions to the Synthesis of Diverse Heterocyclic Scaffolds
Authors: Sunderhaus James D. , Martin Stephen F.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mechanism for Anellation ([2 + 4] Cyclocondensation) of Schiff Bases by β‐Dicarbonyl and β,β′‐Tricarbonyl Compounds in Amphiprotic Media
Authors: Gulyakevich O. V. , Mikhal'chuk A. L.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: CpRuCl‐ and CpCo‐Catalyzed or Mediated Cyclotrimerizations of Alkynes and [2 + 2 + 2] Cycloadditions of Alkynes to Alkenes: A Comparative DFT Study
Authors: Varela Jesus A. , Saa Carlos
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ruthenium‐Catalyzed Isomerization of Terminal Olefins: Applications to Synthesis
Authors: Donohoe Timothy J. , O'Riordan Timothy J. C. , Rosa Carla P.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Traveling the Vitamin B12 Pathway: Oral Delivery of Protein and Peptide Drugs
Authors: Petrus Amanda K. , Fairchild Timothy J. , Doyle Robert P.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phosphonium Coupling in the Direct Bond Formations of Tautomerizable Heterocycles via C—OH Bond Activation.
Authors: Kang Fu‐An , Sui Zhihua , Murray William V.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Glycosyl Sulfur, Selenium, and Tellurium Compounds
Authors: Turnbull W. B. , Fascione M. A. , Stalford S. A.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Glycosyl Halides
Authors: Gunn S. J. , Warriner S. L. , White J. W.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical and Biological Aspects of Narcissus Alkaloids
Authors: Bastida Jaume , Lavilla Rodolfo , Viladomat Francesc
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Germacrone: Occurrence, Synthesis, Chemical Transformations and Biological Properties
Authors: Barrero Alejandro F. , Herrador M. Mar , Arteaga Pilar , Catalan Julieta V.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organotellurium Derivatives: Synthesis, Structure, Supramolecular Associations and SHG Efficiency
Authors: Srivastava Prakash C.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of Biologically Active Biginelli‐type Dihydropyrimidinone Derivatives
Authors: Ahmed Bahar , Keshari Manoj , Habidullah Habidullah
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Quinoxaline 1,4‐Dioxide and Phenazine 5,10‐Dioxide — Chemistry and Biology
Authors: Gonzalez Mercedes , Cerecetto Hugo , Monge Antonio
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Advances in the Syntheses of Quinoline and Quinoline‐Annulated Ring Systems
Authors: Madapa Sudharshan , Tusi Zehra , Batra Sanjay
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spiroketals
Authors: Ley S. V. , Milroy L.‐G. , Myers R. M.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Porphyrins in Diels—Alder and 1,3‐Dipolar Cycloaddition Reactions
Authors: Silva Ana M. G. , Cavaleiro Jose A. S.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses of Small Cluster Oligosaccharide Mimetics
Authors: Franz Andreas H. , Gross Paul H. , Samoshin Vyacheslav V.
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lactonization‐Mediated Glycosylation and Their Application to Oligosaccharide Synthesis
Authors: Kim Kwan Soo , Jeon Heung Bae
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: RNA Interference: From Basic Research to Therapeutic Applications
Authors: Kurreck Jens
Published: March 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Value versus growth stock returns and the value premium: The Canadian experience 1985–2005
Authors: Athanassakos George
Published: March 2009

This paper provides further evidence on the value premium using Canadian data from 1985–2005 and a search process involving both price to earnings (P/E) and price to book value (P/BV) ratios. The study documents a consistently strong value premium over the sample period, which persisted in both bull and bear markets, as well as in recessions and recoveries. Moreover, the paper shows that a P/E based search process did a better job of identifying value stocks and arriving at more consistent and sizeable value premium than did a search process based on P/BVs. Copyright © 2009 ASAC. Published by John Wiley & Sons, Ltd.
Tacrine–Melatonin Hybrids as Multifunctional Agents for Alzheimer's Disease, with Cholinergic, Antioxidant, and Neuroprotective Properties
Authors: Fernández‐Bachiller María Isabel , Pérez Concepción , Campillo Nuria Eugenia , Páez Juan Antonio , González‐Muñoz Gema Cristina , Usán Paola , García‐Palomero Esther , López Manuela G. , Villarroya Mercedes , García Antonio G. , Martínez Ana , Rodríguez‐Franco María Isabel
Published: March 2009

Tacrine–melatonin hybrids are potential multifunctional drugs for Alzheimer's disease that may simultaneously palliate intellectual deficits and protect the brain against both β‐amyloid peptide and oxidative stress. Molecular modeling studies show that they target both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. They are nontoxic and may be able to penetrate the CNS, according to in vitro PAMPA‐BBB assays.

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Tacrine–melatonin hybrids were designed and synthesized as new multifunctional drug candidates for Alzheimer's disease. These compounds may simultaneously palliate intellectual deficits and protect the brain against both β‐amyloid (Aβ) peptide and oxidative stress. They show improved cholinergic and antioxidant properties, and are more potent and selective inhibitors of human acetylcholinesterase (hAChE) than tacrine. They also capture free radicals better than melatonin. Molecular modeling studies show that these hybrids target both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. At sub‐micromolar concentrations they efficiently displace the binding of propidium iodide from the PAS and could thus inhibit Aβ peptide aggregation promoted by AChE. Moreover, they also inhibit Aβ self‐aggregation and display neuroprotective properties in a human neuroblastoma line against cell death induced by various toxic insults, such as Aβ25–35, H2O2, and rotenone. Finally, they exhibit low toxicity and may be able to penetrate the central nervous system according to an in vitro parallel artificial membrane permeability assay for the blood–brain barrier (PAMPA‐BBB).
Cost implications of new treatments for advanced colorectal cancer
Authors: Wong Yu‐Ning , Meropol Neal J. , Speier William , Sargent Daniel , Goldberg Richard M. , Beck J. Robert
Published: March 2009

BACKGROUND:

Since 1996, 6 new drugs have been introduced for the treatment of metastatic colorectal cancer. Although they are promising, these drugs frequently are given in the palliative and are much more expensive than older treatments. The objective of the current study was to measure the cost implications of treatment with sequential regimens that include chemotherapy and/or monoclonal antibodies.

METHODS:

A Markov model was used to evaluate a hypothetical cohort of 1000 patients with newly diagnosed, metastatic colorectal cancer. Patients supposedly received up to 3 lines of treatment before supportive care and subsequent death. Data were obtained from published, multicenter phase 2 and randomized phase 3 clinical trials. Sensitivity analyses were conducted on the efficacy, toxicity, and cost.

RESULTS:

Using drug costs alone, treatment that included new chemotherapeutic agents increased survival at an incremental cost‐effectiveness ratio (ICER) of $100,000 per discounted life‐year (DLY). The addition of monoclonal antibodies improved survival at an ICER of >$170,000 per DLY. The results were most sensitive to changes in the initial regimen. Even with significant improvements in clinical characteristics (efficacy and toxicity), treatment with the most effective regimens still had very high ICERs.

CONCLUSIONS:

Treatment of metastatic colorectal cancer with the most effective regimens came at very high incremental costs. The authors concluded that cost‐effectiveness analyses should be a routine component of the drug‐development process, so that physicians and patients are informed appropriately regarding the value of new innovations. Cancer 2009. © 2009 American Cancer Society.
Lymph node ratio predicts disease‐specific survival in melanoma patients
Authors: Xing Yan , Badgwell Brian D. , Ross Merrick I. , Gershenwald Jeffrey E. , Lee Jeffrey E. , Mansfield Paul F. , Lucci Anthony , Cormier Janice N.
Published: March 2009

BACKGROUND:

The objectives of this analysis were to compare various measures associated with lymph node (LN) dissection and to identify threshold values associated with disease‐specific survival (DSS) outcomes in patients with melanoma.

METHODS:

Patients with lymph node‐positive melanoma who underwent therapeutic LN dissection of the neck, axilla, and inguinal region were identified from the SEER database (1988‐2005). We performed Cox multivariate analyses to determine the impact of the total number of LNs removed, number of negative LNs removed, and LN ratio on DSS. Multivariate cut‐point analyses were conducted for each anatomic region to identify the threshold values associated with the largest improvement in DSS.

RESULTS:

The LN ratio was significantly associated with DSS for all LN regions. The LN ratio thresholds resulting in the greatest difference in 5‐year DSS were .07, .13, and .18 for neck, axillary, and inguinal regions, respectively, corresponding to 15, 8, and 6 LNs removed per positive lymph node. After adjustment for other clinicopathologic factors, the hazard ratios (HRs) were .53 (95% confidence interval [CI], .40 to .71) in the neck, .52 (95% CI, .42 to .65) in the axillary, and .47 (95% CI, .36 to .61) in the inguinal regions for patients who met the LN ratio threshold.

CONCLUSIONS:

Among the prognostic factors examined, LN ratio was the best indicator of the extent of LN dissection, regardless of anatomic nodal region. These data provide evidence‐based guidelines for defining adequate LN dissections in melanoma patients. Cancer 2009. © 2009 American Cancer Society.
Radical nephrectomy surgical outcomes in the University HealthSystem Consortium Data Base
Authors: Mitchell Robert E. , Lee Byron T. , Cookson Michael S. , Barocas Daniel A. , Duke Herrell S. , Clark Peter E. , Smith Joseph A. , Chang Sam S.
Published: March 2009

BACKGROUND:

We sought to determine the impact of radical nephrectomy case volume, hospital size, and geographic region on immediate surgical outcomes for patients undergoing radical nephrectomy in academic centers across the country.

METHODS:

The University HealthSystem Consortium (UHC) Clinical Data Base was queried for data corresponding to patients who underwent radical nephrectomy at 1 of 134 academic medical centers nationwide between 2003 and quarter 2 of 2007 (n = 42,988). Radical nephrectomy case volume (1‐99, 100‐499, and 500 + ), total discharges (1‐49,999, 50,000‐99,999, 100,000 + ), and geographic region (5 categories) were determined for each academic center. ANOVA and the Tukey statistic were used. Length of stay, intensive care unit (ICU) rate, complication (comp) rate, and in‐hospital mortality were analyzed.

RESULTS:

Case volume was a significant predictor of length of stay, ICU, and comp. Mean length of stay was 6.88, 5.61, and 4.76 days, respectively, for centers from lowest to highest case volumes (P < .001). ICU rates for the 3 tiers were 30.77, 17.93, and 12.22 (P < .001). Comp rates were 24.50, 19.40, and 15.48 (P < .001). Tukey analysis revealed a ceiling effect: No differences were seen between the 2 higher case volume groups. Stratification by total discharges revealed differences in ICU rates (P = .001) and comp rates (P = .001). Region of the country had no significant impact on any of the outcome variables in this study.

CONCLUSIONS:

Radical nephrectomy case volume emerged as an important variable in predicting 3 of the 4 outcome parameters in this study. Results suggest that a “critical volume” of cases portends improved surgical outcomes. Cancer 2009. © 2009 American Cancer Society.
Molar Mass, Radius of Gyration and Second Virial Coefficient from new Static Light Scattering Equations for Dilute Solutions: Application to 21 (Macro)molecules
Authors: Illien Bertrand , Ying Ruifeng
Published: March 2009

New equations for static light scattering of dilute binary solutions allow molar mass determination of macromolecules from measurements of scattered intensity ratios between solution and solvent (Ir). In contrast to the standard Carr–Zimm equations, they do not rely on the experimental absolute value of the Rayleigh ratio of a reference liquid. The picture shows a typical plot for the surfactant BRIJ72 in CH2Cl2 (MSupplier=0.359 kg mol−1).

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New static light scattering (SLS) equations for dilute binary solutions are derived. Contrarily to the usual SLS equations [Carr–Zimm (CZ)], the new equations have no need for the experimental absolute Rayleigh ratio of a reference liquid and solely rely on the ratio of scattered intensities of solutions and solvent. The new equations, which are based on polarizability equations, take into account the usual refractive index increment ∂n/∂ρ2 complemented by the solvent specific polarizability and a term proportional to the slope of the solution density ρ versus the solute mass concentration ρ2 (density increment). Then all the equations are applied to 21 (macro)molecules with a wide range of molar mass (0.2<M<8000 kg mol−1). On the studied dataset with M<200 kg mol−1, the new equations clearly achieve a better agreement with supplier M values. For macromolecules (M>500 kg mol−1), for which the scattered intensity is no longer independent of the scattering angle, the new equations give the same value of the radius of gyration as the CZ equation and consistent values of the second virial coefficient.
Dynamic and Structural Properties of Aqueous Arsenic Solutions
Authors: Coskuner Orkid , Allison Thomas C.
Published: March 2009

Aqueous arsenic solutions are important in geochemistry, environmental chemistry, and biochemistry. Thus, studies of arsenic solutions that probe the structure of the hydrated arsenic ion and the behavior of water around As ions have wide‐ranging implications. The mechanisms for water dissociation around three arsenic ions (see picture) and structural details of the resulting aqueous complexes are presented.

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Photoelectrochemical Studies of Gold Electrodes Chemically Modified with Single‐Walled Carbon Nanotubes
Authors: Merli Daniele , Profumo Antonella , Dondi Daniele , Albini Angelo
Published: March 2009

Seeing the light: An electrode is assembled by linking acid‐shortened single‐walled carbon nanotubes with carboxylic groups to a gold surface modified with a cysteamine monolayer. The electrode generates a photocurrent when illuminated with visible light in the presence of an electroactive species (see picture). With an appropriate applied potential the device behaves as a photodiode.

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The preparation, characterization and unique photoelectrochemical characteristics of a gold electrode chemically modified with suitably derivatized single‐walled carbon nanotubes (SWCNTs) are described. The SWCNT–chemically modified gold electrode (CNT‐CME) is assembled by linking acid‐shortened SWCNTs with carboxylic groups at the nanotube ends to a gold surface previously modified with a cysteamine monolayer. A persistent photocurrent is observed when the modified electrode is illuminated with visible light in the presence of an electroactive species (ascorbic acid, AsA). The influence of physical variables (applied potential, light intensity) and of chemical parameters (AsA concentration, pH) on the generated photocurrents is evaluated. With an appropriate applied potential this device behaves as a photodiode.
Dispersed Fluorescence and Delayed Ionization of Jet‐Cooled 2‐Aminopurine: Relaxation to a Dark State Causes Weak Fluorescence
Authors: Feng Ke , Engler Gernot , Seefeld Kai , Kleinermanns Karl
Published: March 2009

Dark state: The photophysics of 9H‐2AP (see figure) depends strongly on the solvent and the temperature. In polar, aprotic solvents the fluorescence quantum yield is lower compared to protic ones. Analysis of the diffuse fluorescence spectra point to the existence of a dark singlet n,pi* state which is long‐lived (1 microsecond).

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