bluuebunny/crossref_metadata_2025 huggingface dataset:
Sheet Metal Forming Analysis of Aluminium Alloy AA6061 using |Altair INSPIRE Form Simulation
Authors:   School of Mechanical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Tharazi Izdihar , Abdul Halim Nurul Hayati ,   School of Mechanical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Mohd Salleh Farrahshaida ,   School of Mechanical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, HP Manurung Yupiter ,   School of Mechanical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Sabtu Amirul Syazani ,   School of Mechanical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Zulkifli Zulaika ,   aSchool of Mechanical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Khalit Muhammad Ilham ,   Department of Mechanical Engineering, School of Engineering, Bahrain Polytechnic, Isa Town 33349, Kingdom of Bahrain
Published: June 2024

Altair INSPIRE Form is a computer simulation developed for designing and modelling sheet metal forming processes. Within the modules, the design and formability prediction can be simulated and optimized. Thus, this study focuses on analysing the formability of sheet metal Aluminium alloy AA6061 by simulating numerically a multistage forming of an end-wall process where the material properties and process parameters gained from the literature were used as input. The geometrical model was validated by comparing its formability with the literature that was simulated by Altair HyperForm. Then, to statistically analyse the influence of forming parameters on formability, Analysis of Variance (ANOVA) was applied with the design of experiment approach using the Response Surface Methodology (RSM). The simulation results observed similar strain rate distributions between Inspire Form and HyperForm under a safe forming process. For the formability of Aluminium alloy AA6061, loose metal zones with wrinkles, excessive thinning up to 23.13%, and the maximum equivalent stress at 414.6 MPa were expected to be generated. These findings clearly explained that forming parameters such as blank holder force and punch velocity have to be carefully controlled for this ductile material. The ANOVA shows a significant influence of coefficient friction and punch velocity on thinning percentages. The likelihood of tearing to form at a higher thinning percentage and its appearance was observed in the Forming Limit Diagram which evaluates its formability. The validation of optimized parameters by simulation work is concluded to be successful as no fracture appeared in this simulation with a small percentage error at 2.19% between the simulation and the predicted value.
The Role of the Faint Young Sun in Prebiotic Chemistry: A Chemical Perspective on Prebiotic Polymerization
Authors:   Pusat Sains Angkasa, Institut Perubahan Iklim, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Tharumen Navaniswaran , Sithamparam Mahendran ,   Pusat Sains Angkasa, Institut Perubahan Iklim, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Satthiyasilan Nirmell ,   Pusat Sains Angkasa, Institut Perubahan Iklim, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Bahari Siti Aminah ,   Pusat Sains Angkasa, Institut Perubahan Iklim, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Chelvanathan Puvaneswaran ,   Institut Penyelidikan Tenaga Suria (SERI), Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Latip Jalifah ,   Jabatan Sains Kimia, Fakulti Sains dan Teknologi, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Mat Jusoh Hussain Afifuddin Husairi ,   Pusat Sains Angkasa, Institut Perubahan Iklim, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia,   Pusat Pengajian Citra Universiti, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Abdullah Mardina ,   Pusat Sains Angkasa, Institut Perubahan Iklim, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Chandru Kuhan ,   Pusat Sains Angkasa, Institut Perubahan Iklim, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia
Published: June 2024

The faint young sun (FYS) was introduced as a paradox by prominent astronomer Carl Sagan dan George Mullen. This paradox posits that the luminosity of the sun 4.6 billion years ago (when it came into existence) was less than 30% of its current luminosity. The variation in solar radiance might have facilitated the Origin of Life (OOL) on Earth by influencing prebiotic chemistry, especially in the formation of prebiotic polyester. Polyester, synthesized from alpha hydroxy acids(ɑHAs), serves as a model studied as a framework that facilitates OOL. Studies indicate that polyester gels can form from dehydration reactions of ɑHAs in wet-dry cycles, potentially initiating prebiotic life. Moreover, various investigations have demonstrated that ultraviolet UV light has been known to initiate prebiotic chemical reactions, as well as produce polyester. However, experiments have been done, but none has truly explored broadband light from the FYS. Furthermore, prebiotic polymerization induced by FYS has not been shown. In this paper, we will discuss about FYS, some research conducted regarding prebiotic reactions induced by UV light, and the prospects of how FYS’ broadband light might be beneficial for prebiotic polymerization involving polyester.
THE FIRST STEPS OF THE PREACHING ACTIVITY OF CHARLES TAZE RUSSELL
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Kharkovshchenko Yevhen , Orlovskyi Roman ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Published: June 2024

This study is aimed at outlining the context of the first preaching company of Charles Taze Russell, the founder of the Watch Tower Society, and the religious movement International Bible Students, which today is called the religious organization of Jehovah's Witnesses. As a result of the study, it was found that in the first half of 1870, Charles Russell and a group of like-minded people, through Bible studies, came to certain conclusions that became the basis of their doctrinal system. During this same period, independent Adventist minister Nelson Barbour and his followers were identified as rethinking the idea of Christ's second coming after their disappointment in 1874. They found the theological basis for a new view that Christ's return had actually occurred, but in an invisible manner. It has been established that the common belief in the invisible manner of Christ's return became the reason for the acquaintance of Charles Russell and Nelson Barbour in 1876. This encounter made Charles Russell open to the importance of studying the prophetic periods of the book of Daniel. It was found that the basis of the interpretation of the prophetic scheme, which he got acquainted with and accepted, was the edited scheme, which was professed by the participants of the movement of William Miller in the 1830s–1844. It is revealed that the new convictions, the realization that the time for the fulfillment of events before the arrival of the Millennial Kingdom has come, prompted Charles Russell to take active action in preaching, for the accomplishment of which he spent his time and money. As a result of the religious activities of Charles Russell and his employees, a significant number of US states were covered by preaching. Because the religious leaders of the day did not agree with the idea of the invisible return of Christ in 1874, Charles Russell's preaching work faced great resistance. At the same time, some noted his positive personal qualities: confidence and courage in public sermons.
Mitral valve calcinosis as an important finding during heart examination
Authors: Filatova Daria A. , Mershina Elena A. , Plotnikova Maria L. , Lisitskaya Mariya V. , Sinitsyn Valentin E.
Published: June 2024

BACKGROUND: Mitral valve calcinosis is a chronic degenerative process in the fibrous structures of the mitral valve. Advanced stages increase the risk of endocarditis and cardiac rhythm disturbances and contribute to cardiovascular mortality. The cause of mitral valve calcinosis is still controversial; however, the contribution of atherosclerosis to its development is currently undisputed. The prevalence of mitral valve calcinosis varies in different age groups and on average is higher in people with cardiovascular disease.
AIM: To assess the prevalence of mitral valve calcinosis in patients undergoing computed tomography angiography and identify the relationship between aortic and mitral valve calcinosis and coronary calcium index and signs of remodeling.
MATERIALS AND METHODS: A retrospective study of 336 patients who underwent computed tomography coronary angiography with intravenous contrast enhancement at the Lomonosov Moscow State University Clinic between November 13, 2020, and May 14, 2022, was conducted.
RESULTS: The prevalence of aortic (16.4%) and mitral (11%) valve calcinosis was high in people undergoing cardiovascular examination, and a relationship was noted between valve calcinosis and coronary calcium index.
CONCLUSION: The detection of mitral valve calcinosis in patients during routine examination is important in predicting further treatment and outcomes because valve calcinosis is an indirect indicator of coronary heart disease risk. Although valve calcinosis is usually an incidental examination finding, it may indicate a high cardiovascular risk and should prompt further evaluation, if clinically necessary.
Liver function assessment based on hepatobiliary contrast agent-enhanced magnetic resonance imaging
Authors: Ageeva Sofiia F. , Sinitsyn Valentin E. , Mershina Elena A. , Rucheva Natalia A. , Petrova Ekaterina I.
Published: June 2024

BACKGROUND: Liver function assessment is very important in clinical practice. The use of magnetic resonance imaging for the anatomical and functional evaluation of the liver is possible in actual clinical practice.
AIM: To examine the possibility of using hepatobiliary contrast-enhanced magnetic resonance imaging for the evaluation of liver function.
MATERIALS AND METHODS: Datasets of patients who underwent gadoxetic acid-enhanced magnetic resonance imaging were retrospectively reviewed. Patients were divided into two groups: group 1 included patients with impaired liver function, and group 2 included those with normal liver function. Based on magnetic resonance imaging in the hepatobiliary phase, the liver parenchyma signal intensity and its ratio to spleen signal intensity and portal vein signal intensity were estimated. Differences among these parameters were compared between groups. The correlation between liver parenchyma signal intensity and laboratory blood tests reflecting liver function (total bilirubin, albumen, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma glutamyl transpeptidase, and prothrombin time) were analyzed.
RESULTS: Datasets of 53 patients (25 men and 28 women, aged 24–84 years) were analyzed. Group 1 included 19 patients, whereas group 2 included 34. The median liver parenchyma signal intensity was 919.05 [669.65; 1258.35] in group 1 and 1525.13 [1460.5; 1631.4] in group 2 (p=0.0000001). The median ratio of liver parenchyma signal intensity to spleen signal intensity was 1.2 [1.04;1.7] in group 1 and 1.7 [1.46; 1.96] in group 2 (p=0.00076). The median ratio of liver parenchyma signal intensity to portal vein signal intensity was 1.44 [1.29; 1.83] in group 1 and 1.6 [1.43; 1.83] in group 2 (p=0.1). The estimated correlation values between liver parenchyma signal intensity and blood tests parameters were as follows: total bilirubin (r=–0.61; p=0.000001), albumen (r=0.13; p=0.61), aspartate aminotransferase (r=–0.57; p=0.000009), alanine aminotransferase (r=–0.44; p=0.001), alkaline phosphatase (r=–0.45; p=0.0007), gamma glutamyl transpeptidase (r=–0.5; p=0.0003), prothrombin time (r=–0.34; p=0.04).
CONCLUSION: The study reflects the ability to assess liver function using indices (liver parenchyma signal intensity and its ratio to spleen signal intensity) derived from gadoxetic acid-enhanced magnetic resonance imaging. However, this study did not confirm the assumed effectiveness of using the liver parenchyma signal intensity to portal vein signal intensity ratio as an index of liver function. A significant inverse correlation was identified between liver parenchyma signal intensity and blood test parameters in reflecting liver function, except for albumin. The results indicate the possibility of using magnetic resonance imaging to assess liver function.
On the anniversary of Professor Vladislav Ivanovich Viter
Authors: Vavilov Alexey Yu. , Khalikov Airat A. , Pozdeev Alexey R. , Proshutin Vladimir L. , Babushkina Karina A. , Kolesnikova Elena V. , Naidenova Tatiana V. , Sashin Evgeniy D.
Published: June 2024

The article is dedicated to the anniversary of the outstanding physician and scientist Vladislav Ivanovich Viter, founder of the Scientific School of Forensic Medicine. It tells about his life path, scientific achievements, and contribution to the development of medicine. Vladislav Ivanovich was born into a family of doctors and devoted his whole life to medicine. He went from a student to a professor and head of the Department of Forensic Medicine. Viter is the author of 400 scientific papers, including 30 books, and has received numerous awards and titles. The article emphasizes the importance of Vladislav Ivanovich’s contribution to the development of forensic medicine and medicine in general. It also noted his personal qualities such as hard work, perseverance, and dedication.
Innovative pedagogical technologies in the modernized teaching of morphological disciplines
Authors: Jakubenko Oksana V. , Astashov Vadim V. , Zayko Oleg A. , Klochkova Svetlana V. , Arnous Mayas
Published: June 2024

The article describes the experience of using innovative pedagogical technologies in teaching morphological disciplines. Moreover, the experience of using innovative pedagogical technologies in teaching morphological disciplines was presented. The need for such modernization was found to be associated with the approval of the updated Federal State Educational Standards of Higher Education and the requirements for the formation of a necessary set of competencies of a future doctor. As a result of mastering the specialty program, the student should have the following competencies: systemic and critical thinking (UC 1), development and realization of project activities (UC 2), self-organization and self-development (UC 6, 7), inclusive competence (UC 9), etc. The block of general professional competencies, including diagnostic and instrumental methods of examination (GPC 4), information literacy (GPC 10), and scientific and organizational activities (GPC 11), must be developed. The use of innovative pedagogical technologies expands the possibilities of preparing students for the updated forms of external audit of their residual knowledge, helps them develop clinical thinking, and more successfully prepares them for the upcoming professional activity.
Chitin/chitosan: bioresources, applications field, production technologies
Authors: Perelygin Vladimir V. , Nekrasova Tatyana A. , Zharikov Mikhail V. , Werner Anna O. , Zmitrovich Ivan V.
Published: June 2024

The present review is devoted to such biotechnologically interesting polymers as chitin and chitosan, which form the cuticle of arthropods and the core of fungal cell wall. Chitosan is a linear polysaccharide containing D-glucosamine and N-acetyl-D-glucosamine residues, which has valuable biological properties. It is a product of deacetylation of chitin. Possessing pronounced muco-adhesive properties and controlled release ability, the chitosan is widely used in delivery of various therapeutic agents, such as anticancer drugs, antibiotics, proteins, nucleic acids, etc. Chitosan nanoparticles, micro- and nanocapsules, as well as hydrogels, can be developed for targeted delivery of drugs to specific organs and tissues. Initially, the attention of biotechnologists was focused on animal chitin, and basic methods for extracting and purifying this biopolymer took shape at this stage. Despite the complexity of the organization of the arthropod cuticle, the chitin in it is not covalently bound to other linear biopolymers and is organized into nanofibrils that form a fairly homogeneous matrix, therefore it is easier to extract than from the mycelium mass of fungi, where this biopolymer is tightly packed into microfibrils bound to the glucan matrix. The main stages of chitin extraction and its further modification into chitosan are deproteinization, demineralization, deacetylation, and the main methods of chitosan purification are filtration, dialysis and reprecipitation. After isolation, chitosan should be dried. To extract chitin from the fungi, the above classical chemical methods are often combined with the methods of “green chemistry” and industrial microbiology. The profitability of the production of chitin/chitosan from crustaceans and edible mushrooms is approximately at the same level. The cost of mushroom products can be reduced by using agricultural or forestry waste as nutrient substrates. This makes the use of fungi as sources of chitin/chitosan in forest regions rather promising.
Glioma of the anterior visual pathway in children. Part II. Current treatment trends
Authors: Alyaeva Oksana O. , Serova Nataliya K.
Published: June 2024

The literature review presents modern treatment aspects for anterior optic pathway gliomas (OPGs), which are low-grade brain tumors accounting for 20%–30% of childhood gliomas, can occur anywhere along the visual pathways and in the development of the surrounding structure, and are predominantly benign. The predominant histological type of tumor in this localization is piloid astrocytoma (PA), less commonly pilomyxoid astrocytoma (PMA). However, the course of anterior OPGs is unpredictable and varies from spontaneous regression to progression with severe visual, neurological, and endocrine disorders, affecting treatment and disease prognosis. Although there have been advances in clinical studies based on histological and molecular genetic analyses, no fundamental changes in survival rates and recurrence-free periods and improvements in functional outcomes have been achieved. Furthermore, no studies have comprehensively analyzed the functional results depending on the management tactics of pediatric patients with anterior visual pathway gliomas. Anterior optic pathway glioma treatment is challenging and complex problem, which depends on the patient’s age, clinical picture, localization, surgical resectability, and histological and molecular genetic study results. It includes surgical treatment, chemotherapy, radiation therapy, the use of targeted therapy drugs, and additional advanced techniques that are still under development and research. Optimal treatment of anterior optic pathway gliomas in children remains a topic of discussion in the current literature.
Utjecaj komercijalnih inokulanata na kemijski sastav i fermentaciju silaže od lucerne
Authors: Uher Darko
Published: June 2024

Krmne mahunarke teško se siliraju, pa je potrebno primijeniti starter-kulturu od odabranih sojeva bakterija mliječne kiseline koji podupiru proces siliranja i sprječavaju nepoželjne bakterijske maslačne fermentacije te time doprinose očuvanju i poboljšanju kvalitete silaže. Cilj istraživanja bio je procijeniti učinke komercijalnih inokulanata na kemijski sastav i fermentaciju silaže lucerne kultivara OS99. Masa lucerne podijeljena je u šest jednakih dijelova (kontrola – silaža bez inokulanta) i silaža tretirana komercijalnim inokulantima (PIO1 – Pioneer 11H50, PIO2 – Pioneer 11AFT, SIL – Silko, BON – Bonsilage alfa i SAL – Sil–All4 × 4), sve silirano u mikrosilosima. Nakon 90 dana od siliranja, silaže su analizirane s obzirom na kemijski sastav te fermentacijske parametre. Udio suhe tvari i sirovih proteina bio je veći, a udio mliječne i octene kiseline bio je značajno (p<0,05) veći u silaži tretiranoj inokulantima PIO1, PIO2, SIL, BON i SAL u odnosu na kontrolu. Silaža lucerne tretirana inokulantima PIO1, PIO2, SIL, BON i SAL imala je niži udio kiselih i neutralnih deterdžentskih vlakana, niži pH te značajno (p <0,05) niži udio maslačne kiseline, alkohola i NH3–N u usporedbi s kontrolom. Rezultati istraživanja pokazali su da komercijalni inokulanti PIO1, PIO2, SIL, BON i SAL povećavaju kvalitetu silaže lucerne kultivara OS99 u odnosu na kontrolu.
Grass-Fed Cattle as an Option to Improve the Sustainability of Cattle Industry in Croatia
Authors: Gantner Ranko , Steiner Zvonimir , Gantner Vesna , Zmaić Lea
Published: June 2024

In Croatia, as well as in many neighboring countries, neither the cattle farmers nor the general public (i.e., the consumers) are familiar with the meaning of the grass- fed cattle farming. This paper’s objective is to present what environmental and consumer-health benefits might arise from this way of cattle farming, along with the expected constrains regarding a lower productivity per animal and per the used land resources. The presented literature review has demonstrated that, when compared to the conventional TMR-fed cattle, the grass-fed feeding manner produces the cattle-derived foods with the greater consumer-related health benefits, has a potential to restore biodiversity in agricultural countryside, causes a lesser environmental pollution due to a lesser pesticide use, improves animal welfare and the beauty of a countryside landscape, decreases the farmers’ operating costs, consumes less fossil fuel per hectare of the utilized land, which is appreciated in climate policies, and has a potential to improve the cattle farmers’ resilience and independence from distant fossil fuels. The grass-fed foods are appreciated by the end-consumers who are willing to pay a price premium for such products. The projected feed and forage consumptions, along with the data on a grass-fed cattle productivity, have indicated a poorer conversion rate of feed DM to milk (1.433 vs. 0.756) and bodyweight gain (12.168 vs. 7.526) in the grass-fed cattle when compared to the TMR-fed, which implies that the grass-fed cattle would require much more land resources per product unit than the TMR-fed cattle. Further research is required to test the productivity of grass-fed cattle (per head and per hectare) in Croatian conditions, as well as to investigate the productivity of Croatian grassland resources.
The Impact of Planting Technology on the Maize Yield
Authors: Banaj Anamarija , Banaj Đuro , Stipešević Bojan , Horvat Dražen
Published: June 2024

The three–year trials of the impact of the planting technology on the maize yield were carried out at the trial sites Jakšić and Tenja. The KWS Intelligens and KWS Kollegas hybrids were used in the research, planted at a standard row spacing of 70 cm, and in the twin rows with a spacing of 48 × 22 cm. In 2020, the highest average grain yield at the site Jakšić in standard planting, with the KWS Intelligens hybrid, was 12.064 t ha–1, and in the twin row planting an increase in yield of +4.17% was recorded. The KWS Kollegas hybrid had the highest difference in grain yield between a standard and twin row planting in 2021 of +7.52%, in favor of the twin row. At the site Tenja, slightly higher grain yields were recorded in all three years of research. The major difference in yield was recorded in 2020 with the hybrid KWS Kollegas, of +8.22%, or 1.115 t more grain, when planting in the twin rows in comparison with a standard planting. The statistical tests indicate that planting in the twin rows at both trial sites obtained statistically significant results in all three years of research concerning the grain yield ha–1, grain weight per ear, and grain moisture content.
Preharvest Germination in Different Wheat Cultivars
Authors: Orkić Vedran , Grubišić–Šestanj Sanja , Ravnjak Boris , Rebekić Andrijana , Petrović Sonja , Vila Sonja , Kiš Darko , Guberac Vlado , Jović Jurica , Kujundžić Sunčica
Published: June 2024

Pšenica je jedna od osnovnih poljoprivrednih kultura za prehranu čovjeka te se koristi u mlinarstvu, prehrambenoj i farmaceutskoj industriji. U poljoprivrednoj proizvodnji postoje razni čimbenici koji utječu na visinu prinosa, a samim time i financijsku dobit, pa je stoga jedan od najvećih čimbenika koji stvaraju velike probleme priježetveno proklijavanje (PHS – preharvest sprouting). Štete koje nastaju uslijed PHS-a u svijetu iznose oko 1 bilijun dolara. Ciljevi istraživanja bili su sljedeći: ispitati proklijavanje na klasu nakon žetve te procijeniti varijabilnost svojstva proklijavanja na klasu uz pomoć molekularnoga markera (Vp1B3). Utvrđene su statistički značajne razlike između ispitivanih kultivara pšenice za svojstvo proklijavanja na klasu. Kod većine kultivara s nižom ocjenom proklijavanja na klasu utvrđena je prisutnost alela od 569 bp (tolerantnost na PHS), a kod većine kultivara s visokom ocjenom proklijavanja na klasu utvrđena je prisutnost alela od 652 bp (osjetljivost na PHS) na Vp1B3 lokusu.
The Sensory Characteristics of Eggs Enriched With the fish and Linseed Oil
Authors: Kralik Zlata , Kralik Gordana , Radanović Ana
Published: June 2024

This research investigates the effect of fish and linseed oils supplemented to the laying hens’ feed on the sensory characteristics of table eggs. The experiment was performed on 480 laying hens of TETRA SL hybrid, which were divided into three groups (K: 5 % of soybean oil, P1: 1.5 % of fish oil and 3.5 % of linseed oil, and P2: 2 % of fish oil and 3% of linseed oil). A sensory analysis of eggs was comprised of an assessment of egg color, smell, taste, and texture and was performed by a panel of tasters (n=52) who administered the triangle test and the hedonic test. The panel determined that there was a significant difference (P<0.05) in taste of eggs between the treatment pairs K: P1 and K: P2 but no significant difference between the treatment pair P1: P2. The most frequently detected difference between the treatment pairs referred to the taste, then to color and smell, and the difference in egg texture between the pairs was not represented that much. An increased amount of fish oil in the hens’ diet increased a sensory perception of egg smell and decreased a sensory perception of taste. The egg taste liking differed significantly between the treatments (P<0.05). Referring to the sensory characteristics of likability of color and odor of eggs, there were no significant differences (P>0.05) determined between the treatments.
COGNITIVE AND CONTENT COMPONENT OF PROFESSIONAL STABILITY OF HIGHER EDUCATION TEACHER
Authors: Конюхова Е.Н.
Published: June 2024

Рассматривается когнитивно-содержательный компонент феномена профессиональной устойчивости преподавателя высшей школы. Представлены результаты диагностики сформированности профессиональных компетенций преподавателей. Исследование показало, что профессиональные компетенции сформированы на достаточном уровне у 59 % участвовавших в диагностике преподавателей, не в полной мере – у 41 %. Большинство респондентов, попавших в группу педагогов, у которых не в полной мере сформированы профессиональные компетенции, имеют возраст от 22 до 35 лет и стаж работы от трех месяцев до девяти лет. В статье предложены формы работы по формированию и развитию профессиональных компетенций преподавателей, определяющих их профессиональную устойчивость.

The article focuses on the cognitive and content component of the phenomenon of professional stability of higher education teachers. The results of diagnostics of the formation of higher education teachers’ professional competencies are presented and mechanisms for their formation and development are proposed. To estimate the level of professional sustainability cognitive and content component formation, we carried out the diagnostics of teachers’ professional competences in the following blocks: 1) knowledge of modern concepts of education; 2) knowledge of the psychological foundations of learning; 3) knowledge of disciplines taught; 4) pedagogical skills; 5) knowledge of normative documents; 6) ability to form students’ educational motivation, 7) application of modern training technologies; 8) implementation of an individual approach to learning; 9) the ability to adequately assess the integrity and effectiveness of the training process, and 10) the ability to form students’ creative conscious and active attitude to the future profession. The study showed that professional competencies were formed at a sufficient level in 59 % of the teachers involved in the diagnosis, not fully – in 41 %. Most of the respondents with underdeveloped professional competencies are between 22 and 35 years of age and have a teaching experience between three months and nine years. The article proposes the forms of work aimed at development of teachers’ professional competences that determine their professional sustainability.
FUNCTIONAL STATES OF STUDENTS UNDER DIFFERENT TRAINING MODES
Authors: Сулейманова Р.Г. , Магомедова У.А. , Гадисова И.Г. , Бартыханова Х.М. , Керимгаджиева У.З.
Published: June 2024

Цель данного исследования заключается в исследовании воздействия различных образовательных режимов на физическое и психологическое благополучие студентов. Мы анализируем как традиционные, так и альтернативные методы обучения, такие как гибкий график, дистанционное образование, блок-схемы и интенсивные курсы. В качестве методов исследования применялся анализ серии опросов группы университета студентов в количестве 50 человек в возрасте от 19 до 21 года. Выборка включает представителей разных факультетов и специализаций, добровольно согласившихся принять участие в обследовании. Результаты подчеркивают важность выбора оптимального образовательного режима и его влияние на эффективность учебного процесса и функциональное состояние студентов. Выявлена роль физической активности, здорового питания, правильной организации дня, эффективного управления стрессом и осознанной само- регуляции как важных факторов, влияющих на функциональное состояние студентов. Эти рекомендации предоставляют студентам необходимые инструменты для поддержания оптимального состояния, независимо от выбранного образовательного режима. Выводы исследования имеют значение как для практического применения в образовательном процессе, так и для дополнительных исследований в области образовательной психологии и физиологии студентов.

The purpose of the study is to investigate the impact of different educational modes on the physical and psychological well-being of university students. We analyze both traditional and alternative teaching methods such as flexible scheduling, distance education, flowcharts, and intensive courses. As research methods we applied an analysis of a series of surveys of the university’s student group. The sample included 50 students aged 19 to 21 years who were the representatives of different departments and specializations. The respondents voluntarily agreed to participate in the survey. The results emphas- ize the importance of choosing the optimal educational mode and its impact on the effectiveness of the educational process and the students’ functional state. We identified the role of physical activity, healthy diet, proper organization of the day, effective stress management and conscious self-regulation as important factors influencing the functional state of students. These recommendations provide students with the necessary tools to maintain optimal performance, regardless of their chosen educational mode. The findings of this study have implications for both practical applications in higher education and additional research in the field of educational psychology and student physiology.
Evaluating the Effectiveness of Gaming Practices in Enhancing Computer Science Terminology Learning among Primary School Students
Authors:   Department of Computer Science, Al-Farabi Kazakh National University, Almaty, Kazakhstan, Alipova Aigerim
Published: June 2024

This research paper investigates the effectiveness of Game-Based Learning (GBL) in enhancing the memorization of computer science terminology and motivation among primary school students. Conducted with a sample of 80 students divided into an Experimental Group (EG) and a Control Group (CG), the study employed a quantitative methodology, including tests, questionnaires, and statistical analyses to evaluate the impact of a custom-developed game, “Rusty Rusty,” on learning outcomes. The findings revealed that students in the EG, who learned through GBL, demonstrated significantly higher memorization skills and motivation levels compared to their CG counterparts, who were taught using traditional methods. The study also explored the theoretical underpinnings of GBL, its practical implications for educators, and acknowledged the limitations of its research approach. With a significant difference in final exam scores and motivation rates, the results affirm the potential of GBL as a more engaging and effective alternative to conventional teaching in primary education. This study delves into the integration of gaming practices as a pivotal educational technology approach, specifically aimed at enhancing computer science terminology learning among primary school students. It underscores the potential of interactive and engaging methods to enhance learning experiences and outcomes, demonstrating how these approaches can make challenging subjects, such as computer science, accessible and appealing to young learners in the digital age.
Neuropsychiatric disorders and antioxidant vitamins E and C supplementation
Authors: Ghodake Santoshi R.
Published: June 2024

The pathogenesis of neuropsychiatric disorders is incompletely understood, which may partly account for the persisting dominance of the syndrome nosology in neuropsychiatry, despite its widely recognized inadequacies. Oxidative stress mechanism have been implicated in the pathogenesis has theoretical appeal, as the brain is considered particularly vulnerable to the damage. The oxidative vulnerability of the brain, suggests that oxidative damage may be a plausible pathogenic candidate. Antioxidants have attracted the attention of clinicians due to therapeutic potential. The author presents an overview of the current literature on antioxidants supplementation approach, particularly vitamin E and C and current evidences in the field of neuropsychiatric disorders. Vitamin E and vitamin C are well known antioxidants that are postulated to protect against damage to biological membranes by their ability to scavenge free radicals. Results of vitamin combinations are found promising and further studies on this combination therapy are suggested.
Study on comparison of electrolytes in hospitalized patients of critical care medicine by automated biochemistry analyzer and arterial blood gas analyzer
Authors: Sushma BJ  , Jat Narendra Kumar , Roy Mohit , Thakuriya Rakesh
Published: June 2024

Critical care medicine department has to assess electrolytes accurately and quickly to initiate the treatment. Blood samples are analyzed in a matter of seconds by arterial blood gas analyzers (ABG), albeit their accuracy is still up for debate. The current study objectives were to estimate and compare the levels of electrolytes (sodium, potassium, and chloride) in hospitalized critical care patients as determined by automated biochemistry analysis and blood gas analyzer and to assess the degree of agreement between the two instruments and obtain information on whether these values can be interchanged.

A prospective hospital based observational study was undertaken after obtaining institutional ethical committee clearance. The study included a total of 195 paired venous and arterial samples from the patients admitted to Critical Care Medicine Unit of NIMS Hospital, Jaipur, India in whom electrolytes were analysed on Arterial Blood Gas (ABG) analyzer and Automated Biochemistry Analyzer (ABA). Analysis was done on ABL555 blood gas analyzer located in the critical care medicine unit and vitros 5600, located in Clinical Biochemistry. Statistical analysis was done using Student’s t test and Pearson’s correlation coefficient test.

A total of 195 samples were analyzed. The mean levels of sodium, potassium and chloride were 136.64 ± 5.44 mmol/L, 3.87 ± 0.523 mmol/L and 100.79 ± 6.65 mmol/L respectively analyzed by ABG analyzer. The mean levels of sodium, potassium and chloride were 136.65 ± 5.81mmol/L, 88 ± 0.543 mmol/L and 100.47 ± 6.41 mmol/L respectively analyzed by ABA. Student’s t test comparison p values for sodium, potassium and chloride were 0.458 (Not Significant), 0.1867 (Not Significant) and 0.0438 (Significant) between the two instruments. The strength of agreement between the two instruments for sodium, potassium and chloride were analyzed using pearsons correlation coefficient. There was strong agreement for all the three parameters between the two instruments and the p value was 0.00001 (highly significant) for all the three parameters.

The results of this investigation showed no discernible differences between the automated biochemistry analyzer and arterial blood gas analyzer measurements of sodium, potassium, and chloride. Clinicians can make critically important decisions by relying on the results of arterial blood gas analysis.
Conceptual aspects of cognitive ergonomics and job design
Authors: Sabauri Tinatin
Published: June 2024

The study of cognitive ergonomics and correct job design is a contemporary topic. This article defines and presents the main issues that ensure effective management of cognitive ergonomics and job design.
Mais do que nunca, a casa: uma experiência errante em cartas
Authors: Costa Victor Anselmo , Kasper Kátia Maria
Published: June 2024

A partir da experiência de trocar cartas com estudantes de uma escola pública durante a pandemia de sars-cov-2 nos defrontamos com a seguinte questão: o que pode uma correspondência pedagógica comprometida com o “tempo livre” e com a educação pública? Na primeira sessão deste artigo discutimos o conceito da forma escolar de Jan Masschelein e Marteen Simons e propomos quatro pistas para explorar as potências da escrita de cartas pedagógicas. Alteridade, amorosidade, encontro e errância são os gestos educativos que emergem destas pistas. Na segunda sessão, discutimos a importância da estesia provocada pela utilização de linguagens artísticas e culturais em nossa correspondência. Finalizamos o artigo de forma descritiva, conduzindo uma leitura em sobrevoo ao conteúdo das cartas, em que temas da disciplina ecologia são interpelados por questões relacionadas aos povos indígenas no Brasil.
Pesquisa clínica, autonomia da vontade e direitos de personalidade: o caso do menino Kauã no Tribunal de Justiça do Rio Grande do Sul
Authors: Andreazza Luís Paulo Petersen
Published: June 2024

A pesquisa clínica com medicamentos visa ao alcance do bem-estar social e do equilíbrio da saúde humana, sendo identificado um significado social dos estudos clínicos que remete à discussão sobre a quem se atribui a responsabilidade pela manutenção do fornecimento de medicamentos após o término do estudo clínico.
Terapias farmacológicas e não farmacológicas no tratamento da Doença de Alzheimer – Uma Revisão Narrativa da Literatura
Authors: Machado Bruna da Silva
Published: June 2024

Introdução: a doença de Alzheimer (DA) é a forma mais comum de neurodegeneração associada ao envelhecimento da população que acarreta grande impacto socioeconômico. Idosos acima de 65 anos são os mais acometidos e os fármacos até o momento para o tratamento visam a melhora dos sintomas e o retardo do progresso da doença. O presente estudo tratou-se de uma revisão narrativa da literatura.Métodos: para a busca dos artigos foram utilizados os descritores “Alzheimer”, “Farmacocinética”, “Farmacologia”, “Agonistas Colinérgicos”, “Receptores de Glutamato”, bulas dos medicamentos e os dados do Instituto Brasileiro de Geografia e Estatística.Resultados e métodos: os fármacos mais utilizados no momento são os que atuam nas vias colinérgicas e glutamatérgicas, esta última usada em casos mais graves da doença. Há também novos medicamentos e terapias alternativas que ainda precisam de estudos adicionais para avaliar sua eficácia, entre eles a imunoterapia.Conclusão: o cenário farmacológico da DA oferta medicamentos onde já se conhece exatamente sua farmacocinética, farmacodinâmica e efeitos colaterais associados, mas pode-se perceber que ainda há opções medicamentosas que precisam de estudos adicionais para futuramente ser uma opção terapêutica, o que mantém a esperança de que ainda se possa encontrar medicamentos com maior eficácia, menos toxicidade e efeitos colaterais.
Distribuição dos Casos de Sífilis Congênita na Região Sudeste Brasileira: Análise Espaço-temporal
Authors: Duarte Santiago Iago Sávyo , Paz Lopes Cecília , Sousa Alexandre Débora Maria , Lima Cândido Estelita , Costa Pires Rener
Published: June 2024

Objetivo: O presente estudo objetiva descrever a situação epidemiológica da sífilis congênita na região Sudeste brasileira de 2016 a 2018, observando se há diferenças significantes nas variáveis analisadas.Método: Trata-se de um estudo de prevalência a partir de dados oficiais do Ministério da Saúde brasileiro. A análise foi conduzida adotando-se testes para comparação de médias e proporções com significância a 0,05.Resultados:  Rio de Janeiro apresentou o maior número de registros no triênio (média: 3.982,3±451,59), seguido por São Paulo (média: 3.902,0±208,2), sendo ambos significativamente maiores que Espírito Santo (média:599,6±40,5). A comparação entre os estados revelou valor significante (p=0,0237). A análise das variáveis revela que os resultados não são significantes para a idade da criança no momento do diagnóstico e para a faixa etária da mãe. Diagnóstico final, realização de pré-natal, escolaridade da mãe e tratamento do parceiro apresentaram resultados significantes em alguns estados. Conclusões: Os resultados diversos quanto à significância dos valores entre os estados demonstram as distintas realidades enfrentadas por cada Unidade Federativa. Constata-se um aumento nas notificações de sífilis na região, o que pode indicar um real aumento ou pode ser resultado da busca ativa de casos efetuada pelo serviço de vigilância epidemiológica.
A percepção do paciente frente aos Cuidados Paliativos
Authors: Marcassi Heloísa Cremonez , Dall’ Oglio Laura Maria , Deina Marina , Coraiola Michelle Simão , Ribeiro Elaine Rossi
Published: June 2024

Introdução: Dialogar sobre o processo de finitude é uma tarefa árdua com a qual as pessoas não estão habituadas. Nesse sentido, os cuidados paliativos representam uma abordagem que visa dar suporte perante o enfrentamento à terminalidade.Objetivo: O objetivo deste estudo foi apreender a percepção de pacientes frente aos cuidados paliativos.Métodos: Consiste em uma pesquisa descritiva  qualitativa, sendo utilizada entrevista semiestruturada gravada, com posterior transcrição para análise de conteúdo com referencial de Bardin.Resultados: A pesquisa foi realizada em hospital na cidade de Curitiba, Paraná/ Brasil, com nove pacientes em cuidados paliativos. Em cada categoria discutiram-se as singularidades expostas pelos pacientes.Conclusão: O acolhimento do paciente pela equipe de profissionais facilitou o enfrentamento da doença por meio da humanização e alívio dos sintomas. Entretanto, o desconhecimento do termo “cuidados paliativos” e a falta de esclarecimento quanto à atual situação dos pacientes foram documentadas de forma significativa.
Avaliação da Estabilidade da Enzima Acetilcolinesterase em Amostras de Sangue Frescas e Congeladas
Authors: Stahl Patrícia , Benedetti Danieli , Silva Juliana
Published: June 2024

Objetivo: avaliar a estabilidade da atividade enzimática da acetilcolinesterase (AChE) em amostras de sangue frescas e congeladas.Materiais e Métodos: a amostra foi composta por um pool de voluntários no qual foi determinada a atividade da AChE. A atividade foi determinada na amostra sem contaminação pelo agrotóxico Diazinon 0,07M (P0/controle) e em três níveis de inibição pelo composto: P1 (7x10-3M), P2 (5,7x10-3M) e P3 (4x10-3M). Avaliou-se a estabilidade das amostras frescas no dia da coleta, bem como 24 e 72 horas após a coleta. As amostras congeladas foram avaliadas após 3, 6 e 8 dias de congelamento.Resultados: nas amostras frescas a estabilidade do controle foi de 24 horas e nas amostras contaminadas com agrotóxico apresentaram menor estabilidade e maior inibição da AChE com o passar do tempo. As amostras congeladas apresentaram boa estabilidade durante 8 dias. Não foi observada diferença significativa entre a atividade da AChE em amostras frescas e congeladas no 3° dia, porém as amostras frescas não foram estáveis.Conclusão: o processamento das amostras frescas pode ser realizado até o 3º dia e as amostras congeladas, embora necessitem de mais testes compreendendo 24 e 48 horas de congelamento, podem ser utilizadas até 8 dias.
Anormalidades cromossômicas identificadas em um serviço de genética médica do interior do Estado de São Paulo, Brasil
Authors: Nascimento Ana Claudia Paesani , De Abreu Tatiane , Liberato Érica Letícia Angelo , Dos Santos Thamires Rosa , Marsiglio Heloisa Pastana , Melo Débora Gusmão
Published: June 2024

Objetivos: Essa pesquisa objetivou determinar a frequência de anormalidades cromossômicas em pacientes atendidos no Ambulatório de Genética Médica de São Carlos, São Paulo, Brasil, e analisar os motivos de encaminhamento destes pacientes.Métodos: Trata-se de estudo retrospectivo, de corte transversal e abordagem quantitativa. Foi realizada revisão dos mapas de atendimento de todos os 792 pacientes atendidos no Ambulatório entre junho de 2006 e dezembro de 2018, com identificação dos pacientes com anormalidades cromossômicas diagnosticadas pelo cariótipo convencional com bandeamento G.Resultados: Anormalidades cromossômicas foram identificadas em 77 pacientes (9,7%). Cromossomopatias numéricas de autossomos ou cromossomos sexuais representaram 75,3% de todas as alterações (58/77). Cromossomopatias estruturais desequilibradas foram identificadas em seis pacientes (6/77; 7,8%) e cromossomopatias estruturais equilibradas em outros seis pacientes (6/77; 7,8%). Heteromorfismos cromossômicos foram encontrados em sete pacientes (7/77; 9,1%).Conclusões: Nossos resultados apontam para frequência de cerca de 10% de pacientes com anormalidades cromossômicas identificadas pelo cariótipo convencional, no contexto de um ambulatório de genética médica geral. Os achados ressaltam a importância da investigação citogenética adequada para diagnóstico e aconselhamento genético familiar nas situações de defeitos congênitos, deficiência intelectual, baixa estatura patológica em meninas, amenorreia primária, infertilidade, abortamento de repetição e suspeita clínica de síndromes cromossômicas.
The Role of Smartphone Addiction on Bed Procrastination and Mindful Eating Behavior in Adolescents from an Islamic Psychology Perspective
Authors: Karimulloh Karimulloh , Azahra Tri Rahayu Syiffa
Published: June 2024

The large number of Muslims who excessively use smartphones, even at night when sleeping and while eating, needs to be reviewed from an Islamic psychology perspective. This research aims to look at the role of smartphone addiction on bed procrastination and mindful eating behavior from an Islamic psychology perspective. This research method is library research using the Al-Qur'an, Al-Hadith, relevant books, and journal articles to analyze inductive data and draw comprehensive conclusions. The research results show that Islam teaches its followers not to overdo any behavior, including using smartphones. Smartphone addiction behavior, which results in delayed sleep and also eating without being mindful, includes behavior of being ungrateful for the blessings of Allah SWT. Islam encourages teenagers to imitate the behavior of the Prophet Muhammad, including sleeping and eating, namely by sleeping after performing the Isha prayer and practicing mindful eating while eating.