bluuebunny/crossref_metadata_2025 huggingface dataset:
Supporting Technologies for COVID-19 Prevention: Systemized Review (Preprint)
Authors: Zhao Zhuo , Li Rui , Ma Yangmyung , Islam Iman , Rajper Abdul M Azam , Song WenZhan , Ren Hongliang , Tse Zion Tsz Ho
Published: May 2021

BACKGROUND

During COVID-19, clinical and health care demands have been on the rapid rise. Major challenges that have arisen during the pandemic have included a lack of testing kits, shortages of ventilators to treat severe cases of COVID-19, and insufficient accessibility to personal protective equipment for both hospitals and the public. New technologies have been developed by scientists, researchers, and companies in response to these demands.

OBJECTIVE

The primary objective of this review is to compare different supporting technologies in the subjugation of the COVID-19 spread.

METHODS

In this paper, 150 news articles and scientific reports on COVID-19–related innovations during 2020-2021 were checked, screened, and shortlisted to yield a total of 23 articles for review. The keywords “COVID-19 technology,” “COVID-19 invention,” and “COVID-19 equipment” were used in a Google search to generate related news articles and scientific reports. The search was performed on February 1, 2021. These were then categorized into three sections, which are personal protective equipment (PPE), testing methods, and medical treatments. Each study was analyzed for its engineering characteristics and potential social impact on the COVID-19 pandemic.

RESULTS

A total of 9 articles were selected for review concerning PPE. In general, the design and fabrication of PPE were moving toward the direction of additive manufacturing and intelligent information feedback while being eco-friendly. Moreover, 8 articles were selected for reviewing testing methods within the two main categories of molecular and antigen tests. All the inventions endeavored to increase sensitivity while reducing the turnaround time. However, the inventions reported in this review paper were not sufficiently tested for their safety and efficiency. Most of the inventions are temporary solutions intended to be used only during shortages of medical resources. Finally, 6 articles were selected for the review of COVID-19 medical treatment. The major challenge identified was the uncertainty in applying novel ideas to speed up the production of ventilators.

CONCLUSIONS

The technologies developed during the COVID-19 pandemic were considered for review. In order to better respond to future pandemics, national reserves of critical medical supplies should be increased to improve preparation. This pandemic has also highlighted the need for the automation and optimization of medical manufacturing.
Putting the Sorting Hat on J.K. Rowling’s Reader: A digital inquiry into the age of the implied readership of the Harry Potter series
Authors: Haverals Wouter , Geybels Lindsey
Published: May 2021

Compared to the large body of research into gender, race and class in children’s literature, there has been little awareness of the social construction of age in this discourse. Analysing age in contemporary fiction for young readers gives insight in how present-day society models (people of) different ages, and given the decisive role that books play in shaping children’s worldviews, such research contributes to our understanding of how age norms are passed on across generations. This article explores the construction of age in J.K. Rowling’s Harry Potter in relation to the age of the implied reader. This case study provides a unique opportunity to study age, because the main characters in every volume ‘grow up’ together with the implied readers. This article traces the correlation between the evolutions in form and content in J.K. Rowling’s Harry Potter series on the one hand and an evolution in the age of its implied readership on the other. After scrutinising existing guidelines pertaining to the ideal age at which to read each book, we conduct our own digital analyses on the style and topics of the texts. As well as providing insight into the evolution of these features in the Harry Potter books, this article contributes to the ongoing discussions on the reliability of readability measures and the desirability of explicit age markers on books for young readers.
GASTRORETENTIVE FLOATING TECHNOLOGY FOR ERADICATION OF HELICOBACTER PYLORI: AN INSIGHT VIEW
Authors: PAHWA RAKESH , BHARDWAJ BIGUL YOGESHVER , SHARMA ARCHANA , PIPLANI MONA , KUMAR MANISH
Published: May 2021

Helicobacter pylori is a virulent human pathogen infecting about 50% of the population worldwide. Being a leading cause of gastric ulcer, duodenal ulcer, gastritis, dyspepsia, gastric tumorigenesis etc., this organism has been the focus of concerted study to establish uncertainty of its genetics, immunopathogenesis and cell biology. Scientists have tried to effectively eradicate this pathogen from the gastrointestinal tract in various manners. Inquest of this venture, gastroretentive drug delivery systems including floating dosage forms have emerged as a boon and offer significantly improved therapeutic effects of different antimicrobial drugs. This article presents an evocative review of the structural features, epidemiological evidences and various pharmacotherapeutics vistas. In addition, various novel gastroretentive dosage forms developed so far to combat Helicobacter pylori infection are also discussed. Comprehensive literature review has been performed for this manuscript by utilizing relevant databases like PubMed, SCOPUS, Web of Science, Science Direct, Google Scholar etc., from 1997 up to the year 2020.
FORMULATION AND OPTIMIZATION OF NATURAL GUM BASED EXTENDED RELEASE TABLETS OF LOSARTAN USING D-OPTIMAL MIXTURE DESIGN
Authors: SAIFEE BATUL , SONI PRAKASH K. , PASWAN SURESH K. , SAINI T. R.
Published: May 2021

Objective: Losartan potassium is one of the widely prescribed antihypertensive drugs administered orally and its extended-release tablet formulations are essentially required for the long-acting effect at reduced dosage frequency. The present research was aimed for the development and optimization of an extended-release tablet of losartan potassium, exploring natural gums, i.e., xanthan gum and guar gum as drug release modifiers.

Methods: The tablet formulation was prepared by wet granulation method and the formulation optimization was done by D-optimal mixture design using Design Expert® software. The independent variables studied were xanthan gum (X1), guar gum (X2) and lactose (X3) taking various combinations of the total amount of gum and ratio of xanthan gum to guar gum under the given constraint range. The dependent (response) variables studied were % drug release in 1h (Y1), 4h (Y2), 7h (Y3) and 10h (Y4). The developed tablets were evaluated for physical properties, i.e., hardness, friability, weight variation as well as the in vitro drug release profiles. For optimization studies, the polynomial equations and response surface plots were generated and the optimized formulation was selected on the basis of maximum desirability value.

Results: The developed tablet formulation was found to possess all physical properties within the desired range and showed sustained release profile with ~80% drug release in 10 h duration. The model fitting studies demonstrated best fit in the zero-order model and the slope value of Korsmeyer–Peppas plot was ˃0.89, suggesting case II transport as a drug release mechanism.

Conclusion: The findings suggested that natural gums-based matrix tablets of losartan could be successfully developed and natural gums can be explored as platform technology as release retardants and in the development of sustained-release matrix tablets of other drugs.
STATE-OF-THE-ART NANOTECHNOLOGY BASED DRUG DELIVERY STRATEGIES TO COMBAT COVID-19
Authors: JOSEPH SHARON K. , M. A. ARYA , THOMAS SACHIN , NAIR SREEJA C.
Published: May 2021

The emerging Coronavirus Disease-19 (COVID-19) pandemic has had a global impact on all important aspects of our society. As it is known, SARS-Cov-2 can withstand up to 72 h in adverse environmental conditions, which can aid its rapid spread. Woefully, an efficacious and approbated vaccine for the SARS-CoV-2 virus remains unavailable, which makes the problem more frightening and presently more complicated bestowing forlorn medical care. Nevertheless, global clinical research is studying several over-the-counter (OTC) drugs approved for other indications to confront coronavirus. Over the past decade, therapeutic nanoparticles have been regarded as a felicitous tool for the efficient and persnickety delivery of therapeutic groups (i.e., drugs, vaccines, siRNAs, and peptides) to the site of infection. They can adequately convey the drug encapsulated nanoparticle to a designated locus without instigating unsought effects. Besides, they acquiesce the use of non-invasive imaging methods to monitor the surface of the infection and the response to treatment. The formulated nanoparticle is apposite for intranasal drug delivery which is a meritorious method to deliver therapeutic moiety for viral diseases affecting the lungs. Applying nanoparticles via intranasal route surmounted several demerits of mucosal administration like circumventing enzymatic degradation of the therapeutic moiety, upgrading and prolonging the action of the drug, etc., and can thus corroborate as an exceptional strategy to encounter respiratory viruses like coronavirus. In this article, we illuminate the promising role of nanoparticles as effective carriers of therapeutic or immunomodulatory agents to help combat COVID-19.

The search criteria used were Pubmed, Medscape, Google scholar, etc and the keywords are coronavirus, nanoformulations, nanoparticles, drug delivery, intranasal delivery, etc. The articles range from 2012 to 2020.
VALIDATED STABILITY INDICATING HPLC APPROACH FOR QUANTIFYING TRICHOLINE CITRATE AND CYPROHEPTADINE SIMULTANEOUSLY IN SYRUP FORMS
Authors: SAHAI MOHINISH , DEVANNA N.
Published: May 2021

Objective: This investigation demonstrates a stability-indicating and reliable “high-performance liquid chromatography” method to simultaneously quantify tricholine citrate (TEC) and cyproheptadine (CRH) in the syrup form and bulk form.

Methods: Successful separation was accomplished using C18 “Agilent column (250 mm × 4.6 mm, 5 μm)” with isocratic type of elution using mobile phase containing 0.1 M NaH2PO4 buffer and acetonitrile at 55% volume and 45% volume ratio, respectively with 1.0 ml/min flow rate. The wavelength sensor was attuned at 263 nm to quantify TEC and CRH.

Results: TEC and CRH peaks were eluted with fine resolution at retention times 1.837 min and 2.936 min, respectively. In the 137.5-412.5 μg/ml and 1-3 μg/ml concentration ranges for TEC and CRH, the calibration graphs were linear, with regression coefficients of 0.9999 and 0.9998, respectively. The suggested "high-performance liquid chromatography" approach has been shown as sensitive, precise, robust, accurate, specific and stability indicating through the resolution of TEC and CRH from its degradation-based compounds.

Conclusion: The established high-performance liquid chromatography technique was effectively extended to the evaluation of TEC and CRH in the combined syrup form and the test results appeared satisfactory.
VIRTUAL TARGET CONSTRUCTION FOR STRUCTURE-BASED SCREENING IN THE DISCOVERY OF HISTAMINE H2 RECEPTOR LIGANDS
Authors: NUGRAHA GERRY , ISTYASTONO ENADE PERDANA
Published: May 2021

Objective: This study aimed to develop validated targets to be employed in structure-based virtual screening (SBVS) to discover ligands for the human histamine H2 receptor (hHRH2).

Methods: The virtual targets construction was initiated by homology modeling with the reference compound ranitidine as the ligand followed by 100 ns molecular dynamics (MD) simulations. During MD simulations, the snapshot with the lowest value of the free energy of binding was selected for further validation by re-docking simulations. All simulations were performed in YASARA-Structure.

Results: The research presented here resulted in one validated target for the SBVS. Additionally, by employing a clustering module in MD simulations analysis in YASARA-Structure, more than ten different virtual targets are also available for further uses.

Conclusion: The virtual targets resulted in this research offer possibilities to construct valid SBVS protocols to identify ligands for the hHRH2.
La dinámica institucional del Congreso en gobiernos sin mayoría: negociación política del Pacto por México y la LXII Legislatura
Authors: Hernández Gutiérrez Luis Rubén
Published: May 2021

El argumento principal del texto es que el sentido del Pacto creado en 2012, fue aprovechar la experiencia institucional acumulada de negociación política en los gobiernos anteriores para intentar trascender la práctica de formar alianzas legislativas coyunturales, construir una coalición amplia y, de esta manera, sacar adelante la agenda de reformas que se consideraba necesaria para nuestro país. La importancia del Pacto radica en que posibilitó la construcción de acuerdos entre partidos políticos para favorecer la colaboración institucional entre los poderes Ejecutivo y Legislativo en lo que respecta al procesamiento de las reformas estructurales que habían sido postergadas en los gobiernos de encabezados por presidentes panistas
Política Nacional Anticorrupción: coordinación de políticas y retos para su implementación
Authors: Camacho Pérez Jason Alexis , Muñoz-Rivero Manrique Emilio
Published: May 2021

El trabajo toma como guía el enfoque de política pública, ya que la naturaleza de tal orientación reside en el estudio y comprensión del denominado ciclo de políticas públicas, el cual ayuda a entender de manera ordenada y casi secuencial cómo se desarrollan las respuestas y acciones de gobierno a través de las diferentes etapas –definición del problema, in-corporación del problema a la agenda, construcción de alternativas, toma de decisión, implementación, evaluación y reformulación o terminación– de una política pública
“Los grandes problemas nacionales”. Aproximaciones a la obra histórica y política de Armando Bartra
Authors: Starcenbaum Marcelo
Published: May 2021

Es un escrito en el que se expresa un análisis de los trabajos históricos y políticos del intelectual Armando Bartra, para evidenciar el lugar privilegiado que en su obra tienen los problemas relativos a la politización de la izquierda contemporánea, el vínculo conflictivo entre la cultura de izquierdas y el nacionalismo revolucionario. El análisis de la selección de textos le permite al autor constatar la delimi-tación de estos conceptos, a través de la concepción de un análisis de la experiencia neozapatista, la reconstrucción del surgimiento del neocardenismo
Mutations and Epidemiology of SARS-CoV-2 Compared to Selected Corona Viruses during the First Six Months of the COVID-19 Pandemic: A Review
Authors: Nzivo Mirriam M. , Budambula Nancy L.M.
Published: May 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus (CoV) disease 2019 (COVID-19). This study compared the genome, mutations, and infectivity/transmissibility of SARS-CoV-2 with selected betacoronaviruses (beta-CoVs). This study further examined the origin, risk factors, and outbreaks caused by beta-CoVs. We searched the following databases for relevant studies: PubMed, Google Scholar, and the World Health Organization COVID-19 database. A close relationship between SARS-CoV-2 and SARS bat-like CoV RaTG13 (98.9%) was found at the amino acid level, followed by pangolin CoVs. Non-synonymous mutations occur at high frequencies in the open reading frame (ORF) 1ab, spike (S) protein, and nucleocapsid. Mutations P323L and D614G in the RNA-dependent RNA polymerase (RdRp) and S protein, respectively, occur at a high frequency globally. Mutations at position 3037 in the nonstructural protein (Nsp) 3, 14408 (RdRp), and 23403 (S) confer transmissibility to SARS-CoV-2. SARS-CoV-2 has higher infectivity and transmissibility than SARS-CoV, which shares the same receptor. Although bats are confirmed reservoirs, intermediate hosts are currently unknown. Smoking, old age, diabetes, cardiovascular diseases, and hypertension have all been associated with COVID-19. Within six months of its outbreak, COVID-19 was reported in all countries worldwide, whereas SARS was reported in 28 countries and Middle East respiratory syndrome (MERS) in 5 countries. However, the fatality rate of MERS (65%) was higher than that of COVID-19 (4.9%) and SARS (6.6%). Identifying the SARS-CoV-2 intermediate hosts will help prevent future outbreaks. Attention should be given to the pangolin CoVs. Variations in the S gene may confer transmissibility and infectivity.
Operationalizing and Measuring Personalized Learning in K-12 Schools: Development and Implementation of an Innovation Configuration Map
Authors: Arrowsmith Heather E , Houchens Gary W , Crossbourne-Richards Trudy-Ann , Redifer Jenni L , Zhang Jie , Norman Antony D
Published: May 2021

In 2012, the United States Department of Education announced the Race to the Top-District grants. One joint award was made to two large educational cooperatives in the same state that together represented 111 mostly rural schools in 22 districts. One of the grant’s identified four essential projects was the implementation of personalized learning. This article describes how the grant’s external evaluation team worked with grantee leadership and school districts to operationalize personalized learning and then develop and implement Innovation Configuration Maps to measure school-level personalized learning environments. Developmental steps, adoption processes, and preliminary school-level results are reported.
Temporal leadership and employee workplace deviance: The role of perceived illegitimate tasks
Authors: Wan Wei , Wang Aimin , Li Li
Published: May 2021

Drawing on the literature on perceived illegitimate tasks, we investigated, with 216 participants, how temporal leadership affects employee workplace deviance. Our findings show that temporal leadership effectively reduced employee workplace deviance. In addition, perceived illegitimate tasks played a mediating role in the relationship between temporal leadership and employee workplace deviance, and goal congruence moderated the indirect effect of temporal leadership on employee workplace deviance through perceived illegitimate tasks. Practical implications and suggestions for future studies are discussed.
Modern approaches to evaluating the efficiency of mining
Authors:   The Far-Eastern Institute of Management – branch of RANEPA, Kolokoltseva A. B.
Published: May 2021

Russia is the largest country in the world and occupies one of the leading places on the planet in terms of natural resources, but the bulk of deposits were explored to some extent more than a quarter of a century ago, back in the Soviet era. Due to the changes in the sources of financing for the reproduction of mineral resources and geological exploration of the subsurface, qualitative and quantitative indicators are reduced by an order of magnitude, which leads to greater risks in the development of mineral deposits. Even despite the large number of scientific papers, the economic situation forces us to search for more modern and multi-parametric methods for evaluating the efficiency of mining. The article considers the main economic methods for evaluating the efficiency of mining, determines their essence and application features. On the basis of conducted analysis, disadvantages and advantages of using the studied methods were identified, and the author's interpretation of the economic assessment of efficiency of mining resources was given.
Comparison of Mechanical Properties of Gypsum with and without Polypropylene Fibers
Authors: XENGO Xheneta , ZİBERİ Bashkim , SYLA Naim
Published: May 2021

Gypsum is a mineral belonging to the group of sulfates, i.e., sulfuric acid, which is often found in Earth's crust. In this paper, two main types of gypsum, gypsum α and gypsum β, with different water content were prepared. Samples with and without polypropylene fibers, with different fiber content and different fiber lengths during preparation, produced in a gypsum factory located in the Debar region, North Macedonia, were studied. Physical properties such as density, porosity, water absorption capability and their kinetics, packing factor, hardening and others were examined using different methods. The main goal of this paper was the determination of mechanical properties of gypsum such as the compressive and flexure strength and the module of elasticity of the gypsum prisms. For the determination of elastic properties, the nondestructive method of ultrasound testing was used. In this test, the strength and quality of a prism is assessed by measuring the velocity of an ultrasonic pulse passing through a gypsum structure. This test is conducted by passing a pulse of ultrasonic wave through a prism and by measuring the time taken by the pulse to get through the structure. Higher velocities indicate good quality and continuity of the material, while slower velocities may indicate gypsum with many cracks or voids. The comparison of the obtained results from these two types of gypsum shows different mechanical and other physical properties.
Gamificação Aplicada à Gestão do Conhecimento em Projetos: Um Mapeamento Sistemático
Authors: Henrique Dias Valle Pedro , Do Carmo Assis Todorov Maria
Published: May 2021

O conhecimento gerado nas diversas organizações é visto como um importante recurso que pode ser utilizado no gerenciamento de projetos. Porém, registrar esse conhecimento é algo muito difícil, já que diversos fatores podem ocorrer ao longo da execução de projetos nas organizações. Nesse contexto, as organizações precisam de mecanismos para integrar e registrar os conhecimentos que são gerados nos projetos das organizações por meio do compartilhamento do conhecimento que é gerado entre os indivíduos e/ou por meio do armazenamento desses conhecimentos em documentos ou sistemas de informação. Nessa perspectiva, a gamificação tem sido explorada como um mecanismo de apoio ao compartilhamento dos conhecimentos existentes para novos indivíduos. Nesse sentido, este trabalho teve como principal objetivo identificar abordagens que utilizam a gamificação como recurso de apoio a gestão do conhecimento. Para isso, um mapeamento sistemático foi conduzido utilizando guidelines bem conhecidas na literatura. Nesse trabalho foram considerados 15 estudos primários para coletar as seguintes informaçõoes: (i) quais elementos de gamificação são utilizados para apoiar a gestão do conhecimento; (ii) quais são os benefícios na utilização da gamificação na gesão do conhecimento; e (iii) quais os tipos de conhecimentos relevantes para as organizações no contexto de gamificação. Como resultado, obteve-se uma visão geral sobre como a gamificação tem apoiado a gestão de conhecimento em projetos.
MEEGA+KIDS: A Model for the Evaluation of Games for Computing Education in Secondary School
Authors: Gresse von Wangenheim Christiane , Petri Giani , Ferreti Borgatto Adriano
Published: May 2021

Teaching computing in schools has become a worldwide trend. This is operationalized through diverse instructional methods, including educational games. As it is essential to systematically evaluate the quality of such games for computing education in school, the objective of this article is to present the design and evaluation of the MEEGA+KIDS model, a customization of the prominent method MEEGA+, a reliable and valid method to evaluate games. It has been tailored to the specific target audience (secondary school) through a participatory design approach by decomposing evaluation goals into measures and defining a standardized measurement instrument in the form of a self-assessment questionnaire. Results of a reliability and validity analysis of the model, based on a sample of 90 students, show evidence of its reliability (Cronbach’s alpha α=.882) and a first indication of its validity. The MEEGA+KIDS model can, thus, support game creators, instructors and researchers during the game design process and contribute to their improvement and effective adoption in practice.
Um Jogo Sério de Aventura sobre a Interação com os Índios Xokleng durante a Colonização de Ibirama/SC
Authors: Vahldick Adilson , Giachini Euler
Published: May 2021

A disciplina de História objetiva equipar os alunos com capacidades de refletirsobre eventos passados para que entendam o contexto presente e não repitam os mesmos erros. O jogo, descrito nesse artigo, permite que o aluno vivencie as três primeiras décadas da colonização de Ibirama. Duas turmas (n=35) foram usadas para avaliar a abordagem no uso do jogo. Para uma das turmas foi lecionada uma aula sobre o assunto antes do jogo. Os testes estatísticos apresentaram uma melhora significativa de ambas as turmas após a experiência de jogo. Ainda, comparando o conhecimento adquirido entre os alunos que jogaram e os que tiveram aula, os primeiros apresentaram melhor desempenho. Isso resenta uma abordagem eficiente de aprender fatos, datas e vultos para que o professor consiga atingir o objetivo principal das aulas de História.
Construção de jogos não digitais por alunos – um relato de experiência
Authors: Reis da Silva Thiago , Dutra da Silva Leilson , Leonardo Duarte Garcia Luiz , Darcio Noleto Silva Renato
Published: May 2021

Este artigo apresenta os resultados de uma experiência de desenvolvimento dejogos não digitais em uma disciplina de Informática Educacional com 120 discentes dos cursos de Licenciatura Plena em Matemática e Física. Os participantes puderam refletir sobre o impacto da utilização desse método criativo no processo de ensino eaprendizagem, exercitando na prática a definição de um conceito de jogo como solução a problemas relacionados com as disciplinas citadas. Os alunos demonstraram compreender os conceitos apresentados, além de manterem-se engajados na realização das atividades. Os resultados favorecem a apresentação dos conteúdos e se manifestam como uma possibilidade relevante para auxiliar o processo de ensino e aprendizagem dos conteúdos abordados.
Aprendizagem móvel: uma proposta de letramento literário com auxílio de recursos digitais
Authors: Mendes da Silva Nataniel , Altina Silva Ramos Maria , Manir Miguel Feitosa Márcia
Published: May 2021

O presente trabalho é resultado de uma das etapas de uma pesquisa de doutoramento sobre a integração de metodologias ativas e TIC para a promoção de experiências de aprendizagem na disciplina de literatura no Ensino Médio. Adotamos aqui, a partir de uma pesquisa bibliográfica, o paradigma do letramento literário para o ensino e aprendizagem de literatura. Em seguida, por meio de uma pesquisa exploratória e descritiva, buscamos, na literatura e na Web, aplicações para dispositivos móveis que possam enriquecer a aprendizagem de literatura. Como resultado, apresentamos uma proposta de ensino e aprendizagem do conto “Um rastro do teu sangue na neve”, de Gabriel García Márquez, que integra uma metodologia para o ensino, tecnologias móveis e estímulo a uma aprendizagem ativa. O texto selecionado faz parte do livro Doze contos peregrinos, publicado em 1992.
End-user centred Adaptation Process of an Educational Exergame to Mobile Platforms
Authors: Benites de Cequeira Bernardo , Nice Ferrari Barbosa Débora , Batista Mossmann João
Published: May 2021

This work presents the educational Exergame “The Incredible Adventures ofApollo & Rosetta in Space” adaptation process to mobile platforms, specifically Tablets. The Exergame was developed for Elementary School children in the school context, presented in previous work. The objective of this work is to propose a combination of three distinct end-user centered techniques in the process of the game adaptation: 1) evolutionary model of software development aimed for games; 2) non-participant observation on game applications with voluntary participants; 3) semi-structured interview with the participants. The methodology allowed the project’s development team to constantly evaluate the game adaptation through prototypes and user tests with four voluntary participants. These user tests were done in pairs during three sessions, with 1- hour session per week. As the results indicated, this end-user centered development enabled an effective portability process of the game between platforms.
Mapeamento sistemático da literatura sobre a questão da autonomia do estudante, na óptica de Otto Peters, em softwares educacionais
Authors: Luiz de Pádua Ferreira André , Romão Gonzales Gustavo , Piva Dominguez Hamilton
Published: May 2021

Neste trabalho apresenta-se um mapeamento sistemático da literatura, com o objetivo de identificar e analisar como a questão da autonomia, na concepção de Otto Peters, é abordada, ou não, em estudos sobre software educacional, voltados ao ensino a distância, publicados entre 2015 e 2019, do ponto de vista de pesquisadores e profissionais da área de engenharia de softwares educacionais. Para tanto, adotouse a metodologia proposta por Petersen, e utilizou-se a plataforma Parsifal. Após levantamento, categorização e análise dos dados, constatou-se que os modelos de desenvolvimento e avaliação de software educacional presentes nos estudos encontrados pouco, ou nada, exploram o papel desempenhado pela autonomia em processos de ensino–aprendizagem, na modalidade a distância.
O ensino de pensamento computacional através de um jogo de tabuleiro em ambiente desplugado: relato de experiência de formação docente
Authors: Dall Agnol Anderson , Gusberti Crístian , C. Bertagnolli Silvia
Published: May 2021

Este artigo tem o objetivo de apresentar o processo de elaboração, aplicação e avaliação de um jogo de tabuleiro denominado Planetar, o qual tem por finalidade explorar de forma prática os quatro pilares do pensamento computacional (PC). Como metodologia, utilizou-se a pesquisa bibliográfica, a revisão sistemática sobre PC e um estudo de caso. Para o desenvolvimento do jogo foi adotado o processo de desenvolvimento de jogos educacionais chamado ENgAGED. O principal resultado identificado com a avaliação do jogo foi o aumento do interesse por parte dos participantes em ensinar PC na educação básica. Além disso, a execução do jogo também revelou que atividades lúdicas podem ser empregadas no engajamento de professores.
Uma Revisão Sistemática de Literatura sobre Autoavaliação de Pensamento Computacional de Jovens
Authors: Rodrigo de Quadros Martins Amilton , Lobato Miranda Guilhermina , Antonio da Silva Eloy Adelmo
Published: May 2021

O objetivo deste estudo foi realizar uma Revisão Sistemática de Literatura sobre autoavaliação de Pensamento Computacional de estudantes com idades entre 10 e 15 anos. O foco da revisão foi o da autoavaliação feita por meio de escalas, questionários ou testes de conhecimento. Começamos por fazer uma revisão do conceito de Pensamento Computacional, seguida dos resultados da revisão, contendo trabalhos, métodos, instrumentos utilizados e resultados alcançados. Concluímos que já existem instrumentos validados para medir o Pensamento Computacional na sua multidimensionalidade: uns para avaliar o conhecimento ou a transferência de conhecimento, outros a percepção e atitude dos estudantes face a este construto. Como trabalhos futuros, serão usados os achados para a proposta de um sistema de autoavaliação de Pensamento Computacional.
Possibilidades e limites na criação coletiva de artigos da Wikipédia: o artigo “Vitor Marinho de Oliveira”
Authors: Ramyssés Vieira Dias Leon , Malina André , Telles Silvio , Miarka Bianca , Celeste Barreto de Azevedo Ângela
Published: May 2021

No presente estudo, discutiu-se, a partir da análise da criação do artigo “Vitor Marinho de Oliveira”, – um intelectual vinculado à área sociocultural da Educação Física – o fenômeno da Wikipédia, uma enciclopédia organizada em hipertexto e de colaboração cooperativa. Para tal discussão, descreveu-se o processo de criação e submissão do artigo na Wikipédia, apontando os limites e as possibilidades, bem como a interação com a própria plataforma. Utilizou-se como referencial teórico as concepções de Álvaro Vieira Pinto sobre a tecnologia, além de autores que trataram especificamente da Wikipédia. Como principais resultados, foram encontradas limitações para publicação de artigos na Wikipédia, embora os critérios de criação coletiva do conhecimento, tratando-o como um bem público e com difusão gratuita, atenda a uma perspectiva crítica da tecnologia. Para além disso, recomenda-se aos pesquisadores da Educação Física a massificação de publicações no ciberespaço visando preencher essa lacuna e dar usufruto aos leitores da Wikipédia sobre questões relevantes da área, incluindo o conhecimento dos seus principais intelectuais.
SARS-CoV-2 RNA stability in saliva and dry swabs for storage and transport at ambient temperature for at least 9 days: A cost efficient and practical alternative
Authors: Alfaro-Núñez Alonzo , Crone Stephanie , Mortensen Shila , Rosenstierne Maiken Worsøe , Fomsgaard Anders , Marving Ellinor , Nielsen Sofie Holdflod , Jørgensen Michelle Grace Pinto , Cohen Arieh S. , Nielsen Claus
Published: May 2021

During the current COVID-19 pandemic, different methods have been used
to evaluate patients suspected with infection of SARS-CoV-2. In this
study, we evaluate the longevity of saliva and dry swab samples to
retain SARS-CoV-2 for storage and transport at different environmental
settings. Our results show that at ambient temperature of 20°C,
SARS-CoV-2 RNA remains stable for up to 9 days giving a long span of
time for transport and storage without compromising clinical results.
Additionally, this study demonstrates that sali­­­va and dry swabs
specimens can also be stored at -20°C and +4°C for up to 26 days without
affecting RT-qPCR results. Our data is relevant for low-and
middle-income countries, which have limited access to rapid refrigerated
transport and storage of samples representing an economical alternative.
Finally, our study demonstrates that dry swabs provide clear advantages
over using transport medium.
Soil Water Stress Overrides the Boosting Effect of iWUE from Rising CO2 and temperature in Determining Plantation Mortality in Semi-arid Cold Area
Authors: Jia Guodong , Chen Lixin , Yu Xinxiao , Liu Ziqiang
Published: May 2021

The counteractive influence of atmospheric CO2 enrichment and drought
stress on tree growth results in great uncertainty in growth patterns of
planted forests in cold semi-arid regions. We used tree-ring chronology
and carbon isotope analysis to track ecophysiological processes in
reaction to environmental factors over the past four decades of Populus
simonii plantations in cold semi-arid areas in northern China. Our
results showed that the boosting effect of the rising atmospheric CO2
concentration (Ca) on iWUE and stem growth was more significant in
declined stands. However, the increased iWUE did not negate tree dieback
when water stress was present. Therefore, the BAI and iWUE deviation of
different health status trees started from a very early age. Climatic
factors showed limited influences on the stem growth of the poplar
plantations. The inaccessibility of deep soil water due to site-specific
soil conditions rendered the trees exposed to chronic soil water stress
and constrained stomatal conductance and reduced the CO2 fertilization
effect. Consequently, these stands experienced a lower stem growth rate.
In summary, we suggest that soil moisture conditions the iWUE and growth
sensitivity to global warming and thus portrays site-specific decline
episodes of different degrees in drought-prone areas.
A newborn with Aortico-left Ventricular Tunnel mimicking Sinus of Valsalva Aneurysm
Authors: AKBAY SENAY , EKICI Filiz , KARDELEN FIRAT , BULUT MUHAMMET , Mutlu Zeynep , ARSLAN Gökhan
Published: May 2021

Aortico-left ventricular tunnel (ALVT) is a rare congenital cardiac
anomaly and constitues of less than 0.1% of all congenital cardiac
defects (1). ALVT is described as an abnormal connection between the
ascending aorta and the left ventricul which originates commonly above
the right sinus of valsalva. Most patients are diagnosed with an ALVT
during early infancy (2). Although transthoracic echocardiography (TTE)
is more effective in diagnosis of ALVT, misdiagnosis rate was 17.1%
(3). Sinus of valsalva aneurysm (SVA) is frequently confused with ALVT
(3). We report a term female newborn with SVA in echocardiographic
examination but in surgery she was diagnosed with ALVT.
Spinal Cord Tumor Presenting with Abdominal Pain: A Case Report
Authors: Alassaf Anood , Shami Rana Al , Rayahi Jehan Al , Mifsud William , Kharazi Khalid Al , Nashwan Abdulqadir
Published: May 2021

Three years old boy presented with recurrent severe abdominal pain. He
was treated for constipation and the pain resolved. Later he developed a
limitation of neck movements. Investigations revealed a spinal cord
mass. After surgical resection, histopathology confirmed pilocytic
astrocytoma.
The Deterrent Effect of Insider Trading Enforcement Actions
Authors: Davidson Robert H. , Pirinsky Christo
Published: May 2021

We analyze whether exposure to an SEC insider trading enforcement action affects how insiders trade. We find that following an insider trading enforcement action at one firm, exposed insiders earn significantly lower abnormal profits from their trades at other firms compared to non-exposed insiders. The deterrent effect is stronger when a fellow insider is convicted, and is similarly significant both pre- and post-SOX. Following the enforcement event, exposed insiders do not trade less frequently, but do trade significantly fewer shares per trade. Insiders who have witnessed an enforcement action have a lower probability for future conviction than their unexposed peers.

Data Availability: Data are available from the public sources cited in the text.

JEL Classifications: G14; G40; K42.
Analyzing asthma education and clinical practices to optimize parental health literacy: Gap analysis
Authors:   , Dodenberg Heidi
Published: May 2021

Pediatric patients in northern BC have some of the highest asthma prevalence rates compared to children in other areas of the province. Adequate parental health literacy skills are particularly important to make informed health management choices when caring for children with asthma. In this project, a gap analysis process was followed, and three evidence-informed practice gaps related to pediatric asthma care were identified. Findings highlight the need for increased asthma education and parental health literacy resources to address concerns mentioned during stakeholder engagement. Four key recommendations were formulated regarding parental health literacy assessments, clear language requirements for written asthma materials, access to specialized care resources, and adaptation of current asthma education models. In conclusion, the development of a working group that includes asthma and health literacy stakeholders, is the next step to address the findings of this project and improve the overall asthma health outcomes for children in northern BC.
The effects of primary care accessibility and continuity of care on less-urgent emergency department use
Authors:   , Fraess-Phillips Alexander
Published: May 2021

Background/Aims. Since the early 2000s, Canada’s primary care system has undergone substantial reforms, including the incorporation of interdisciplinary teams and strategies to optimise accessibility. However, the effects of primary care accessibility and continuity of care on less-urgent emergency department (ED) use are unclear. Three studies were undertaken to investigate the effects of primary care accessibility and continuity of care factors on less-urgent ED use. Methods. Study One employed a cross-sectional analysis of responses to the Canadian Survey of Experiences with Primary Health Care to predict self-reported ED visit avoidability; Study Two employed a longitudinal time-to-event analysis of responses to Ontario’s Health Care Experience Survey linked with subsequent National Ambulatory Care Reporting System data to predict medically assessed less-urgent ED use; and Study Three employed time-series analyses of presentations to two northern British Columbia EDs following changes in walk-in clinic coverage. Results. Study One (n = 2,625) found no significant associations between self-reported ED visit avoidability and all measures of primary care accessibility and continuity of care. However, rural respondents reported greater ED visit avoidability. Conversely, Study Two (n = 34,686) found that all accessibility factors were significantly associated with medically assessed less-urgent ED use, including the presence of a regular PCP, the regular source of care, and the availability of after-hours care through the PCP. However, time with the same PCP was not associated with medically assessed less-urgent ED use. Rurality was also found to moderate the effect of after-hours care accessibility, with only rural respondents reporting a beneficial effect. Finally, Study Three found that changes in walk-in clinic coverage resulted in short-term impacts on less-urgent ED use, with a walk-in clinic closure resulting in an immediate increase in less-urgent presentations and an opening resulting in an immediate decrease. Conclusions. The findings of Studies Two and Three provide evidence that primary care accessibility factors are associated with medically assessed less-urgent ED use; however, the findings of Study One suggest that these factors do not influence self-perceived ED visit avoidability. Future studies should consider this discordance when measuring the impact of primary care accessibility on less-urgent ED use.
The waiting period: Challenges and opportunities to support caregivers and persons with dementia during transitions to long-term care
Authors:   , Horner Ashley
Published: May 2021

Transitions to long-term care are significant and often challenging experiences for older adults with dementia and their caregivers, with waiting lists a common occurrence due to an aging population and a limited supply of long-term care beds. To better understand the complexities related to transitions to long-term care and inform clinical practice, a comprehensive project was undertaken and included an integrative literature review and a gap analysis of local practices in the interior of British Columbia. The literature review and gap analysis findings were analyzed and presented thematically through interrelated themes, including key concepts surrounding the phases of a transition, caregiver coping, and professional support. Four key recommendations arose from this project regarding continuity and coordination of care, discharge planning, post-discharge care, and evaluation. The strengths, limitations, and implications of this project are discussed, including next steps to mobilize knowledge related to the recommendations and influence evidence-informed changes in practice.
Global Threats to the Development of Civilization in the 21st Century. VII Cartesian readings. Part 1
Authors:   Национальный исследовательский университет  «Московский институт электронной техники»  Институт философии Российской академии наук  Философское общество «Диалектика и культура»  Российская академия народного хозяйства и государственной службы при Президенте Российской Федерации  Белорусский национальный технический университет Университет Калабрии (Италия), Team of authors MIET
Published: May 2021

The materials of the conference reflect the results of applied and creative research of the scientific and educational community in the fields of philosophy, psychology, pedagogy, physical-mathematical and natural science knowledge. The aim of the conference is to identify and consider clusters of global threats in the systems of nature, society, and man. The author's team is represented by recognized scientists and young researchers from Russia, Belarus, Kazakhstan, Germany.
Global Threats to the Development of Civilization in the 21st Century. VII Cartesian readings. Part 3
Authors:   Национальный исследовательский университет  «Московский институт электронной техники»  Институт философии Российской академии наук  Философское общество «Диалектика и культура»  Российская академия народного хозяйства и государственной службы при Президенте Российской Федерации  Белорусский национальный технический университет Университет Калабрии (Италия), Team of authors MIET
Published: May 2021

The materials of the conference reflect the results of applied and creative research of the scientific and educational community in the fields of philosophy, psychology, pedagogy, physical-mathematical and natural science knowledge. The aim of the conference is to identify and consider clusters of global threats in the systems of nature, society, and man. The author's team is represented by recognized scientists and young researchers from Russia, Belarus, Kazakhstan, Germany.
Del paisaje cultural al patrimonio territorial, y viceversa: una conversión necesaria para un proyecto de paisaje desde el patrimonio
Authors: Merino del Río Rebeca
Published: May 2021

El artículo se centra en el necesario proceso de traducción de los valores patrimoniales e identitarios del paisaje cultural a los sedimentos materiales que forman el patrimonio territorial para un proyecto de paisaje. Por medio de un análisis comparativo-descriptivo apoyado en las nociones del paisaje cultural y del patrimonio territorial se trata de descifrar el tipo de relación entre ambos conceptos. Se toma como referencia la conceptualización propuesta por los autores de la Società dei Territorialisti/e para el proyecto integrado de territorio, en la que el significado extensivo del patrimonio territorial recoge los valores patrimoniales e identitarios del paisaje. La alineación con los supuestos territorialistas persigue lograr una integración efectiva de los valores paisajísticos cuando operamos sobre el territorio mediante el proyecto de arquitectura y tener una repercusión sobre el paisaje, aun cuando no exista un marco normativo o regulatorio propenso a la innovación en esta materia.
Análise de composto mercadológico em uma empresa de autoelétrica de Ituiutaba – MG
Authors: Araújo Luma Naiara de Souza , Silva Jussara Goulart da
Published: May 2021

Com as políticas governamentais de incentivo ao consumo de produtos industrializados, incluindo os automóveis, houve o crescimento significativo da concorrência no setor de Auto elétrica nos últimos anos, e, consequentemente, o surgimento de diversas empresas. Com o surgimento de várias empresas em um mesmo setor do mercado, estas necessitam estabelecer estratégias na conquista e fidelização de seus consumidores. Dentre estas estratégias o marketing tem sido uma importante ferramenta. O presente trabalho teve como objeto de estudo uma empresa de autoelétrica de Ituiutaba – MG, tendo como objetivo analisar as estratégias de marketing (composto mercadológico) adotadas pela empresária. A metodologia adotada foi a aplicação de entrevista estruturada, e as teorias levantadas foram através de pesquisa teórica documentadas por outros autores. As informações coletadas na entrevista foram analisadas à luz do referencial teórico, sendo realizado um comparativo com as estratégias adotadas pela empresa e nas conclusões foi realizado uma análise sobre as estratégias adotadas pela empresa e sua eficácia.
Palavras-Chave: Marketing. Composto Mercadológico. Autoelétrica.
Interest Rate Modelling in the Presence of Discontinuities and its Sensitivities
Authors: Udoye Adaobi M. , Ogbaji Eka O. , Akinola Lukman S. , Annorzie Maurice N.
Published: May 2021

Interest rate paths experience discontinuities in the presence of certain factors. Much of the work on interest rate modelling has no consideration for effects of such unexpected occurrences in real life. A good risk manager needs to have a better model that considers possibility of unexpected occurrences. In this paper, we discuss step by step extension of Vasicek model to both jump model and jumpdiffusion model using Itô’s formula as the major tool. We also derive the greeks ‘delta’ and ‘vega’ that measure sensitivity of the interest rate with respect to both changes in its initial interest rate and volatility in an interbank rate.