bluuebunny/crossref_metadata_2025 huggingface dataset:
Interfaz Gráfica Intuitiva para el Procesamiento de Señales EEG
Authors:   Facultad de Ciencias Físico- Matemáticas, Benemérita Universidad Autónoma de Puebla, Santillán Guzmán A. , Ramírez Uriarte H. Z. ,   Ingeniería en Sistemas, Instituto Tecnológico Superior de Eldorado, Oliveros Oliveros J. J. ,   Facultad de Ciencias Físico- Matemáticas, Benemérita Universidad Autónoma de Puebla, Morín Castillo M. M. ,   Facultad de Ciencias de la Electrónica, Benemérita Universidad Autónoma de Puebla, Ramírez Díaz H. ,   Ingeniería en Sistemas, Instituto Tecnológico Superior de Eldorado
Published: September 2023

El presente artículo trata sobre el desarrollo de una nueva interfaz gráfica para el procesamiento de señales electroencefalográficas (EEG) por medio de técnicas simples como filtros digitales (pasa-bajas, pasa-altas, pasa-banda y banda-eliminada), técnicas de descomposición de señales (Análisis de Componentes Independientes, ICA por sus siglas en inglés) y la combinación de ICA con filtros pasa-bajas. Una de las ventajas de esta herramienta es que los comandos, así como las etiquetas y ayuda están en español. Asimismo, cuenta con un ambiente amigable e intuitivo para el usuario y es de fácil uso, permitiendo su manipulación por personas poco familiarizadas con MATLAB, plataforma donde se implementó la interfaz
Evaluación del tremor Parkinsoniano mediante la descomposición y el análisis de señales mioeléctricas
Authors:   Universidad Autónoma de Querétaro, Vázquez Aguilera Salvador Aguistín , Pérez Rámirez C. A ,   Universidad Autónoma de Querétaro, Amézquita Sánchez J. P ,   Universidad Autónoma de Querétaro, Gonzalez Pérez G. ,   Universidad Autónoma de Querétaro
Published: September 2023

Este trabajo se enfoca en la evaluación del tremor parkinsoniano (TP) mediante la descomposición completa empírica de modos con ruido adaptativo y su análisis, a fin de lograr aislar y cuantificar la señal correspondiente al TP. Para este fin, se utilizan dos electromiógrafos, colocados en los músculos involucrados con el TP, para adquirir las señales eléctricas de los músculos, mismas que se descomponen en funciones intrínsecas de modo (IMF). Al emplear la transformada Hilbert, es posible conocer la amplitud y frecuencia instantánea de cada IMF, permitiendo detectar la IMF correspondiente al TP, con lo que es posible hacer la evaluación de los pacientes.
Estimación de la Hemoglobina Oxigenada y Desoxigenada en el Cerebro por Espectroscopia en el Infrarrojo Cercano
Authors:   Departamento de Ingeniería Eléctrica, Universidad Autónoma Metropolitana-Iztapalapa, Pineda Corona K. M. G , Jiménez- Alaniz J. R ,   Departamento de Ingeniería Eléctrica, Universidad Autónoma Metropolitana-Iztapalapa
Published: September 2023

En el presente trabajo se determinan las concentraciones de hemoglobina oxigenada y desoxigenada en el cerebro a partir de señales adquiridas por Espectroscopia en el Infrarrojo Cercano (NIRS por sus siglas en inglés, Near Infrared Spectroscopy), utilizando interpolación de los datos para separar la información perteneciente a cada longitud de onda, de dos fuentes de luz, a 850 nm y 750 nm, ambas en un sólo canal. Posteriormente se aplicó el método de los cuartiles para disminuir valores atípicos, seguido de la implementación de un filtro pasa bajas. Por último, se utilizó la ecuación de Beer-Lambert modificada para estimar los cambios relativos de concentración de oxihemoglobina y desoxihemoglobina en el tejido. El procesamiento se realizó en Matlab, diseñando una interfaz gráfica de usuario para su manipulación
Evaluación de la Respuesta Cardíacay Cerebral ante Estresores Cognitivos y su Regulación con Biofeedback
Authors:   Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, Rojas- Sánchez D. L , Dorantes Méndez G. ,   Facultad de Ciencias, Universidad Autónoma de San Luis Potosí
Published: September 2023

Los efectos que el estrés prolongado puede tener sobre el organismo han sido ampliamente estudiados, sin embargo, es necesario profundizar en el conocimiento sobre los mecanismos de acción que el cuerpo ejerce para lidiar con esta situación, contribuyendo así, a desarrollar técnicas que no sólo permitan mejorar el afrontamiento inmediato, sino que funcionen como un verdadero método de prevención de enfermedades cardiovasculares y/o psicológicas. En este trabajo se evalúa la respuesta en el Sistema Nervioso Central (SNC) y el Sistema Nervioso Autónomo (SNA) ante estresores de tipo cognitivo en 22 sujetos, 11 hombres y 11 mujeres, y se miden los cambios en su desempeño mediante el análisis de los ritmos cerebrales y la Variabilidad de la Frecuencia Cardíaca, utilizando el control de la frecuencia respiratoria como técnica de biofeeback. Se encontró que existe un aumento significativo en la activación, mayormente, del lóbulo frontal izquierdo después de controlar la respiración, al igual que en la del SNA, lo que podría inferir una mejora en el desempeño sistémico de los individuos.
Implementación de un algoritmo de identificación de fuentes como ayuda en el diagnóstico de epilepsias focales
Authors:   Facultad de Ciencias de la Electrónica, Benemérita Universidad Autónoma de Puebla, Centeno Bautista M.A , Morín Castillo M. M ,   Facultad de Ciencias de la Electrónica, Benemérita Universidad Autónoma de Puebla, Ramírez Díaz H. ,   Sistemas Computacionales, Instituto Tecnológico Superior de Eldorado, Oliveros Oliveros J. J ,   Facultad de Ciencias Físico- Matemáticas, Benemérita Universidad Autónoma de Puebla
Published: September 2023

El presente trabajo tiene como finalidad la implementación de un algoritmo basado en modelos matemáticos cuasi estáticos de medio conductor, que permitan realizar una identificación espacial del foco epiléptico a partir de lecturas electroencefalográficas. Dicha implementación es en un FPGA (Field Programmable Gate Array), programado en lenguaje VHDL, este algoritmo mejorará así la ubicación del área afectada. Para validar el algoritmo se usaron datos creados sintéticamente a través de modelos matemáticos para generar una fuente con forma de función campana y datos electroencefalográficos semi-simulados, donde a la función campana se le hizo una superpsición de un registro real
Mapeo estadístico del área de lenguaje y su evolución tras tumor cerebral primario: Un estudio de RMf
Authors:   Instituto Tecnológico y de Estudios Superiores de Monterrey, Segura Morgado A , Marrufo Melendez O. R ,   Departamento de Neuroimagen, Instituto Nacional de Neurología y Neurocirugía "MVS"
Published: September 2023

El mapeo estadístico paramétrico es una técnica ampliamente utilizada para la cuantificación y análisis de datos específicos en neuroimágenes funcionales obtenidas por medio de Resonancia Magnética funcional (RMf). En el presente trabajo se empleó dicho proceso estadístico para la evaluación del desempeño de determinada porción de la corteza cerebral, específicamente el área encargada de la función del lenguaje. El desempeño registrado en el lóbulo temporal se examinó posteriormente a un año de observación en la existencia de un glioma grado II. Se observó que el cerebro desarrolló una reorganización en sus funciones corticales para prevenir una disminución en la función neurolingüística
Desarrollo e implementación de algoritmos con imágenes de tensor de difusión para evaluar la conectividad cerebral
Authors:   Universidad de Guadalajara, Cumplido Bernal José Manuel , Orozco González José Roberto ,   Universidad de Guadalajara, Ramírez Hernández Norma ,   Universidad de Guadalajara, Hernández Montelongo Rosaura ,   Universidad de Guadalajara
Published: September 2023

Las imágenes con tensor de difusión son una técnica de la resonancia magnética que permiten cuantificar el grado de anisotropía de los protones de Hidrogeno en los tejidosen vivo. La tractografía es un procedimiento que se usa para poner de manifiesto los tractos neurales (axón), su estimación posicional en áreas cerebrales de las fibras tiene amplias implicaciones potenciales en los campos de la neurociencia cognitiva. Este trabajo presenta un algoritmo usando a la Imagen de Tensor de Difusión DTI para la evaluación de la conectividad cerebral mostrando el espacio ocupado de los tractos cerebrales en cada área de interés.
Diseño y desarrollo de un prototipo de monitoreo de signos vitales portátil para la atención básica en comunidades de difícil acceso
Authors:   Facultad de Matemáticas, Universidad Autónoma de Yucatán, Callejas Tavera A. , Molino Minero-Re E. ,   IIMAS, Universidad Nacional Autónoma de México, Sánchez Domínguez I. ,   IIMAS, Universidad Nacional Autónoma de México
Published: September 2023

El desarrollo de la tecnología en el campo de la bioingeniería, ha permitido generar dispositivos para la medición de parámetros clínicos de forma sencilla, con buen desempeño y de fácil interacción con el usuario, además permite tener equipos más ad-hoc y compactos. El presente trabajo muestra el diseño y construcción de un prototipo de medición de signos vitales, para la atención básica en zonas de difícil acceso y carentes de infraestructura médica en la península de Yucatán. En la implementación se utilizaron sensores para la medición de la temperatura, oxigenación y ritmo cardíaco de los pacientes que lo requieran, además se hizo uso de la tecnología de microcontroladores para la adquisición y procesamiento de la información, así como de la tecnología Bluetooth para el envío de los datos a la interfaz de despliegue. La metodología se dividió en hardware y software, en donde se describe el funcionamiento lógico del algoritmo de adquisición y la electrónica necesaria para el prototipo. El proyecto se encuentra en la fase de pruebas de funcionalidad, en donde se realizan lecturas de los sensores para posteriormente desplegar los resultados en la interfaz gráfica en el móvil. El prototipo ha generado resultados que han permitido ejecutar ajustes para disminuir el error en la medición de los parámetros, así también se observó que se obtiene una mejor medición en el dedo índice mostrando una estabilidad en los datos obtenidos durante intervalos de adquisición de diez minutos
Is it Possible to Increase the Quality of Sexual Life After Spontaneous Birth?
Authors: Brezeanu Dragos , Brezeanu Ana-Maria , Tica Vlad-Iustin
Published: September 2023

The decrease in number of vaginal births may also be due to the discomfort caused by the episiotomy wounds.

Episiotomy wounds are characterized by discomfort, stinging, vulvodynia.

The decrease in immunity, the increase in vaginal pH during pregnancy and pregnancy, can cause the appearance of bacterial vulvovaginitis and can lead to poor healing of the episiotomy wound.

The patients will be initially evaluated by means of a questionnaire at 24 hours postpartum and then reevaluated at 7 days, when the suture material is removed, by completing the same questionnaire. Bacteriological vaginal secretion examination will also be collected both at 24 hours postpartum and at 40 days.

Visual scales will also be used (REEDA scale, VANCOUVER), at 7 days and at 40 days.

Thus, starting from the question, is postpartum sexual life influenced by episiotomy wounds, we will try to find an answer to this question by applying a questionnaire prepared by us.
Full Potential Linearized Augmented Plane Wave Calculations of Electron and Positron Energy Levels in TlBr and TlCl
Authors: Bousahla Mohammed Alaa , Bousahla Mohammed Nadir , Bousahla Zouaoui , Khachai Houari , Bendjilali Hadjer , Benkatlane Aissa
Published: September 2023

Theoretical research was conducted on the energy levels of electrons and positrons in zinc-blend TlBr and TlCl using the first-principle full potential linearized augmented plane wave method based on the gradient generalized approximation GGA. The study involved the calculation of electron and positron band structures which provided predictive data on several properties such as positron mobility, positron affinity, diffusion constants, effective masses, and positronium work function.
Using Local Ecological Knowledge of Fishers to Identify the Presence and Habitats of Angelsharks in Albanian Waters
Authors: Bakiu Rigers , Peculaj Artenisa , Krstinic Patrik
Published: September 2023

The Mediterranean Sea is a hotspot for shark and ray extinctions and is home to the following three angelshark species: sawback angelshark Squatina aculeata, smoothback angelshark Squatina oculata, and common angelshark Squatina squatina. We conducted a questionnaire-based survey in four coastal regions of Albania, Shëngjin (Lezhë), Vlorë, Himarë (Sarandë) and Durrës, with the aim of collecting historical and current data on angelshark catches in the Albanian seas (Adriatic and Ionian Seas). Although the occurrence of common angelshark was reported by Croatian fishermen in the Adriatic Sea, we included the other two species in our study. The number of observations was minimal, although this is the first study of angelshark species sightings in Albania. It will establish a baseline study that will allow further work on the conservation of these regionally extinct and highly endangered species.
Beatific Satisfaction
Authors: Luke Sean
Published: September 2023

This past decade has seen an increased interest in the nature of Jesus’ atonement. How does a Jewish man’s death from 2000 years ago atone for sin? In this paper, I attempt to provide a model that integrates the best insights from some of the major models put forth and philosophical reflections on the nature of justice. First, I employ Jonathan Edwards to argue that creation’s purpose is to communicate God’s beauty. To live justly is to live along the grain of God’s purposes—to make one’s life a communication (or display) of the beauty of God. I then defend this theory of justice and put forth my model. As I see it, Jesus offers up his life, death, and resurrection as aesthetic icons that uphold and restore the display of God’s beauty in creation. I proceed to show how this model captures the best of several other models. Key Terms: Beauty, Trinity, Atonement, Aesthetics, Justice
Retrospective Analysis of 81 Feline Lymphoma Cases Diagnosed in Surgical Biopsies in Latvia (2011-2020)
Authors: Geine-Romanova Lilija , Houtana Ilze Matise-Van
Published: September 2023

Lymphoma (also known as lymphosarcoma) is a malignant tumor accounting for 20-30% of all neoplasms in cats. There have been no previous studies summarizing trends and characteristics of feline lymphoma in Latvia. The aim of this retrospective study was to determine the prevalence and characteristics of feline lymphoma cases among biopsy submissions to a private veterinary pathology service in Latvia. Data were retrieved by selecting records from Latvian cats diagnosed with lymphoma between 2011 and 2020, including signalment, clinical history, and type of lymphoma (anatomical classification, cellular morphology). In the 10-year period, the mean prevalence of lymphoma among feline biopsy submissions was 4.8% (range 1.9 – 7.2) without upwards trend. Lymphoma was most common in mixed breed (67%), middle-aged (median 8 years) cats with a slight male predominance (56%). Among purebred cats the development of lymphomas was observed at an earlier age. The predominant anatomical type was alimentary lymphoma (53%) followed by extranodal (38%) and multicentric (7%) lymphoma. Majority of alimentary lymphomas were in the small intestine (73%) and 88% of gastrointestinal lymphomas were transmural with remaining cases limited to mucosa (12%). Overall, representation of anatomical types of lymphoma in Latvian cats was similar to those reported elsewhere; however, the subset of intestinal mucosal lymphoma in our study was underrepresented. This finding suggests that until 2021 intestinal mucosal lymphoma was uncommonly considered as a differential diagnosis for cats with enteritis therefore biopsies from such cats were not performed. This study will help Latvian veterinarians to improve diagnostic work-up of lymphoma cases.
Minangkabau Language as Ethnic Identity in Digital Era
Authors: Oktavianus Oktavianus
Published: September 2023

This study aims to research Minangkabau language as an  ethnic identity in this digital era. The researcher did the study in five areas in West Sumatra. It is a qualitative study in which all language phenomena contributing to the validity of findings are considered. Data are collected through participative and nonparticipative observations. The data for this study are in the form of written and spoken language observed in the domain of families, public and cyberspaces. The researcher had discussions and interviews through participative observation. Taking notes and photos of written and printed Minangkabau language are done through nonparticipative observation. The researcher also observed Minangkabau language attitude through nonparticipative observation. The result of the study indicates that the productivity and creativity of using the Minangkabau language in family domains, public and cyberspaces strengthen the role of the Minangkabau language as an ethnic identity. Cultural setting and the needs to advertise local products are among the factors which trigger the use of the Minangkabau language as the symbol of Minangkabau identity.
Mitologi dan Peranannya dalam Pemaknaan Artefak Purbakala: Studi Kasus Kapak Perunggu di Pura Puseh Timbul, Desa Pupuan, Kecamatan Tegalalang, Gianyar
Authors: Puja Gusti Ngurah Ary Kesuma , Jayadi I Kadek Surya
Published: September 2023

This study discuss about the bronze axe which is found in Banjar Timbul, Pupuan Village, Tegalalang District, Gianyar Regency. The artifacts originating from the perundagian period were chosen as the object of study in this research because there is an interesting relationship between the pre-historic heritage site and the meaning that the people of Banjar Timbul believe in the current era. The relationship is analyzed using a theory  of cultural assimilation which reads that a culture experiences a blend that eliminates the characteristics of the original culture that forms a new cultural pattern. The results of this study show that 1). The Bronze Axe in Banjar Timbul has shifted in function as well as its meaning by the community; 2). The mythology becomes a strong influential aspect in the shift of the bronze axe function in Banjar Timbul; 3). That behind the mythology of the Bronze Axe there are a numorous of hidden values, including: a symbol of protection, the majesty of ancestors, and a symbol of unity.
Transitivity Analysis in English for Logistics: A Systemic Functional Linguistic Study
Authors: Septiana Ponia Mega , Yeni Yuliyanti Ai , Sari Titania
Published: September 2023

This study discusses the transitivity process. transitivity helps us in understanding the relationship between subject, object, and action in a sentence. This research aims to determine the process type of English clause in English for Logistics Books by Grussendorf (2009). The data is obtained from six reading comprehension articles contained in the book. The main theory used a transitivity system based on Halliday & Matthiessen (2014b). The method used qualitative description. The result of this research states that four types of processes are used in this research. They are the material, mental, relational, and verbal processes. The dominant frequency of occurrence process in this research is the mental process as much as at 35%. This research may involve ESP teaching process, especially for Logistics Business Students.
Plan y acciones para la recuperación del ANP de Cuatrociénegas, Coahuila
Authors:   Instituto Mexicano de Tecnología del Agua, Breña Naranjo Agustín
Published: September 2023

El IMTA ha estado colaborando en actividades para lograr la recuperación gradual del sistema hidrológico de Cuatrociénegas y la conservación de sus ecosistemas acuáticos y terrestres.
ВЛАСНІ НАЗВИ В УКРАЇНСЬКОМУ ПІСЕННОМУ ФОЛЬКЛОРІ: ДО ПРОБЛЕМИ СЕМАНТИКИ
Authors: КОЛЕСНИК Наталія
Published: September 2023

Стаття присвячена проблемі семантики власних назв, зокрема особливостям лексичного значення народнопісенних онімів. Незважаючи на те, що початки дослідження семантичного статусу імені сягають ледь не доби античності, мовознавці й досі в поглядах на цю проблему не можуть дійти згоди. Труднощі вирішення цього складного питання зумовлені багатьма як об’єктивними, так і суб’єктивними чинниками. До об’єктивних, окрім властивих онімам засадничо особливостей сигніфікації, віднесемо: залежність характеру онімної семантики від специфіки референції в межах різних онімних розрядів і класів; різну реалізацію смислових потенцій власної назви на рівні мови й мовлення; відмінні умови онтологічного буття власної назви на різних етапах розвитку української системи називання тощо. До суб’єктивних чинників належить вибір різних підходів до розгляду питання специфіки лексичного значення онімів. З цього приводу особливий інтерес для дослідника задекларованої проблеми мають фольклорні власні назви, семантична специфіка яких насамперед виформовується відповідно до семантичної специфіки власної назви загалом, а, з іншого боку, зазнає трансформацій у лоні фольклорної мови як такої. Проведений аналіз засвідчив, що семантичний потенціал фольклорних власних назв у пісенних текстах доволі різний. З одного боку – змінні, контекстуально-специфічні оніми. Обсяг їхнього інтенсіоналу коливається від мінімального – інформації про семантичний клас, до якого належить позначуваний ними референт (якщо йдеться про буття цих назв у друкованих текстах) і до максимального під час конкретного виконання тексту, коли обсяг їхньої інформаційної насиченості може перевершувати інтенсіонал загальних назв. Інші фольклорні оніми – це оніми-константи, унікально-специфічні найменування з потужним конотативним потенціалом, чию багату семантичну структуру формують мовні, мовленнєві й позалінгвальні компоненти. Вважаємо, що вивчення особливостей семантики фольклорних онімів поглибить розуміння семантичного статусу власних назв, механізмів та принципів онімної номінації загалом та матиме сприятливий вплив на розуміння природи оніма як такого.
Transmission of Flower Traits and Fertility in Black Rose x Hybrid Tea Rose Cross Combination
Authors: Kılıç Tuğba , Kazaz Soner
Published: September 2023

Breeding studies of scented cut roses have gained significance recently. The Black rose, a naturalized old garden rose in Türkiye, is a valuable genetic resource for breeding programs due to its pleasant scent. This study investigated the fertility of the Black rose (Rosa odorata cv. Louis XIV, Halfeti rose) as a seed parent and its ability to transmit flower traits to offspring. Four commercial cut rose varieties with known pollen germination rates were used as pollen parents. Each combination underwent at least 33 pollinations, and the fruit set rate, the average seed number per fruit, and the seed germination rate were examined. Both parents and one-year-old F1 progeny were evaluated for petal number, scent, and flower color traits during two flowering periods. Cross-pollination resulted in fruit set rates ranging from 70.21% to 100.0%, average seed numbers per fruit ranging from 5.0 to 10.0, and seed germination rates ranging from 4.42% to 21.69%. Morphological characterization revealed that 5.05% of the progeny exhibited moderate to intense scent, 42.42% had sour cherry-colored petals, and petal numbers ranged from 9 to 54. Considering the overall efficiency of rose breeding programs, the findings demonstrate the promising fertility of the Black rose and its relative success in forming efficient combinations with hybrid tea roses. However, it also suggests that the Black rose is not as successful in transmitting the scent to its offspring as in transmitting the flower color.
Geopolitical «Borderliness» as a Factor in Ukraine’s Positioning in International Relations: the Experience of Ukrainian Discourse at the Beginning of the XXI Century
Authors: Pashkovsky P. I.
Published: September 2023

The article considers the problem of the phenomenon of geopolitical «borderliness» as a factor in the positioning of Ukraine in international relations within the Ukrainian scientific discourse of the early XXI century. The definition of the concept of geopolitical «borderliness» has been presented. It is shown that Ukraine is an average regional power, which is characterized by a «borderliness» geopolitical position. On the modern Ukrainian territory, the Euro-Atlantic, Eurasian, Islamic massif and, accordingly, the «super-ethnic frontiers» of the Western European, Slavic and Islamic civilizations intersect. Concepts of the genesis of ideological and sociocultural differences within Ukrainian society in the regional dimension have been characterized. It is substantiated that the foreign policy orientation of Ukraine has always been a derivative of the interaction of the Euro-Atlantic, Eurasian and Black Sea (South-Eastern) paradigms, which necessitates adherence to the «orientation priority» in international political positioning. It follows from this that it is expedient for the Ukrainian state to be guided by a non-bloc strategy. According to Ukrainian researchers, the entry of Ukraine into allied relations with one of the competing poles can lead to a strategic conflict with another center of power and negative consequences for Ukrainian statehood. To prevent this from happening, Ukraine was recommended to pursue a foreign policy on the basis of a neutral status and the principles of «optimal multi-vector approach». This was confirmed by the Ukrainian sociological research. The geopolitical and socio-cultural «borderliness» determines the «split» of Ukrainian society, which is manifested in the foreign policy orientations of residents of different regions. According to Ukrainian sociologists, traditionally the majority of the population of the West of Ukraine and about half of the Center supported the European integration vector. At the same time, about half of the inhabitants of the Center and the majority of the population of the South and East of Ukraine were supporters of the development of relations with Russia and the Eurasian vector of integration. As the only option for foreign policy positioning that would unite the Ukrainian society of different regions, the achievement of national agreement through a compromise was noted, this was possible only if Ukraine pursued a policy of neutrality and «optimal multi-vector approach».
Relationship between autoimmune diseases and serum basal immunoglobulin E levels in patients with common variable immunodeficiency
Authors: Kılınc Mehmet , Colkesen Fatih , Evcen Recep , Sadi Aykan Filiz , Yıldız Eray , Onalan Tugba , Yılmaz Ergun Ummugulsum , Akkus Fatma Arzu , Arslan Sevket
Published: September 2023

Background: Autoimmune diseases can occur at any time in patients with common variable immunodeficiency (CVID). However, the relationship between low immunoglobulin E (IgE) levels and autoimmune diseases in patients with CVID remains poorly understood. Objective:
We aimed to determine the relationship between autoimmunity and low IgE in patients with CVID. Methods: This retrospective cohort study was conducted by using data that had been collected from 62 adult patients with CVID between April 2012 and December 2021. Serum basal
IgE levels were compared between patients with and patients without autoimmune disease. Results: Overall, 23 of the 62 patients with CVID (37.1%) had at least one autoimmune disease (CVID-O). Autoimmune cytopenias, mainly immune thrombocytopenic purpura, were observed in
half of all the patients. Other autoimmune diseases present among the patients included rheumatological diseases, inflammatory bowel diseases, lymphoma, granulomatous lymphocytic interstitial lung disease, autoimmune hepatitis, alopecia, and multiple sclerosis. Serum IgE levels were measured
at the time of diagnosis; IgE was undetectable (<2.5 IU/mL) in 82.6% of the patients with CVID-O (n = 19). The median (interquartile range) serum IgE value in the patients with CVID-O was 2 IU/mL (1‐16 IU/mL), which was significantly lower than the median serum IgE value in patients
with CVID and without autoimmune disease (p < 0.001). Low IgE levels in patients with CVID-O were an independent risk factor for the development of autoimmune disease in patients with CVID (odds ratio 3.081 [95% confidence interval, 1.222‐7.771]; p = 0.017).
Conclusion: Low serum IgE levels were associated with the development of autoimmune disease in patients with CVID. The monitoring of serum IgE levels in patients with CVID may be useful in the early diagnosis and treatment of autoimmune diseases.
Characteristics and management of hypersensitivity reactions with rabbit anti-thymocyte globulin in pediatric patients
Authors: Islamoglu Candan , Arman Bilir Ozlem , Ok Bozkaya Ikbal , Demirel Ali Can , Toyran Muge , Ozbek Namık Yasar , Dibek Misirlioglu Emine
Published: September 2023

Background: Anti-thymocyte globulin (ATG) has been successfully used for decades to prevent graft versus host disease before hematopoietic stem cell transplantation (HSCT) as a part of conditioning regimen. However, sometimes hypersensitivity reactions may limit its use.
Objective: To evaluate hypersensitivity reactions experienced during rabbit-ATG infusion among children and present successful desensitization protocol. Methods: The medical records of pediatric patients who were given rabbit-ATG treatment at our tertiary
center hospital HSCT unit between 2019 and 2022 were reviewed retrospectively. Diagnosis of the patients, age at the time of HSCT, gender, presence of hypersensitivity reaction to rabbit-ATG, and management were evaluated. Characteristics of the reaction and presence of hypersensitivity reaction
to other drugs were also noted. If performed, desensitization protocols were evaluated retrospectively. Results: We evaluated 81 patients; 66.6% of them (n = 54) were boys. The mean age of the patients was 8.78 ± 5.48 years. Hypersensitivity to rabbit-ATG was seen
in six patients (7.4%). Four of them (4.9%) had anaphylaxis; two (2.4%) had urticaria. Intradermal test performed to every patient before the first dose of ATG infusion was detected a positive result in 1 patient (1.2%) . None of these seven patients had allergic reactions to other drugs before.
Successful ATG desensitization was performed in five patients by using a 12‐16 step protocol due to patients’ reaction severity. Conclusion: This study aimed to evaluate hypersensitivity reactions with rabbit-ATG in children. A successful desensitization protocol
with rabbit-ATG is presented. Desensitization must be performed with an experienced team very carefully in the absence of alternative drug.
Proton-pump inhibitors are associated with an increased risk of asthma: A nationwide nested case-control study
Authors: Wang Wei-Ting , Li Cheng-Yuan , Chang Yun-Ting , Bai Ya-Mei , Tsai Shih-Jen , Chen Tzeng-Ji , Chiou Shih-Hwa , Chen Mu-Hong
Published: September 2023

Background: Proton-pump inhibitors (PPI) are among the most widely used drugs worldwide. However, the association between PPI use and the risk of asthma remains unclear. Objective: To investigate the association between PPI use and subsequent asthma risk.
Methods: We included participants from the Taiwan National Health Insurance Research Database between 1999 and 2013. Patients who used PPIs and experienced new-onset asthma (n = 20,344) were assigned to the case cohort and matched in a 1:1 ratio with controls who did not subsequently
develop asthma. PPI use was defined as > 30 cumulative defined daily doses (cDDD); non-PPI use was defined as ≤ 30 cDDDs. The Charlson Comorbidity Index (CCI) score was used for clinical prognosis and comorbidity adjustment. Multivariate Cox regression models were used for the calculation
of adjusted odds ratios (OR). Results: There was a significant and dose-dependent association between PPI use and the risk of developing asthma. The adjusted ORs were 1.24 (95% confidence interval [CI], 1.15‐1.33), 1.39 (95% CI, 1.28‐1.50), and 1.61 (95% CI,
1.43‐1.81) for the male subject with 31‐120 cDDDs, 120‐365 cDDDs, and >365 cDDDs, respectively, compared with PPI nonusers. Men were at higher risk of developing asthma with longer PPI use compared with women. Stratified analyses based on the PPI type showed that exposure
to lansoprazole, pantoprazole, omeprazole, and esomeprazole was associated with subsequent asthma risk. Conclusion: Extended use of PPIs was found to be linked to an increased risk of asthma development. This association remained consistent across different age groups,
sexes, demographic factors, indications for PPI use, CCI scores, and other atopic diseases. However, further prospective studies are required to elucidate the causal mechanisms involved.
The COVID-19 impact on severe uncontrolled asthma costs and biologic use
Authors: Khan Najm S. , Rubin Elizabeth , McKenna Bernard , Palowitch Bernard L. , Sonnenberg Frank , Argon Judith , Panettieri Reynold A.
Published: September 2023

Background: Patients with severe uncontrolled asthma (SUA) overwhelmingly contribute to the economic burden of asthma and may require biologic therapy. However, the impact of the CoronaVirus Disease of 2019 (COVID-19) on asthma costs and biologic use has yet to be evaluated.
Objective: The objective was to test the hypothesis that SUA costs and biologic use decreased during the pandemic. Methods: We analyzed medical costs and biologic use in patients with SUV from January 2017 to December 2021, by using claims data from a large
managed care organization and electronic health record data from Robert Wood Johnson Barnabas Health, according to provider specialty. Results: Of the 3817 managed care organization enrollees within Robert Wood Johnson Barnabas Health with a primary diagnosis of asthma,
348 were identified as having SUA. A nested sample of 151 patients revealed that 50% were managed by primary care physicians (PCP) and specialists, 43% by PCPs only, and 4% by specialists only. The total costs of the claims were $10.8 million over 5 years ($2.2 million per year),
with 60% generated from patients seeing PCPs and specialists, 27% from PCPs only, and 15% from specialists only. During the pandemic, total average costs decreased for all care groups (34% PCP-only patients and 45% for both specialist-only and PCP and specialist patients). Inpatient and outpatient
costs also decreased and were lowest for patients who saw specialists and highest for patients who saw PCPs and specialists. In contrast, prescription costs increased during the pandemic. Biologic use was steadily increasing until a twofold decrease was observed during the pandemic. Thirteen
patients were on biologics: two were managed by PCPs, four by specialists, and seven by both. Conclusion: Inpatient and outpatient costs decreased during the COVID-19 pandemic, but prescription costs increased. Biologic use was increasing among patients with SUA before
the pandemic but then drastically decreased and remained lower during the observational interval.
Intencionalidad argumentativa suposicional escrita para tratar de explicar un texto literario en bachillerato
Authors: Hernández Rodríguez Ernesto
Published: September 2023

Esta investigación analiza la intencionalidad argumentativa escrita de 34 estudiantes bachilleres al tratar de asumir una postura y sustentarla, a partir de suposiciones sobre el contenido relacionado con la muerte de la protagonista en la novela Las batallas en el desierto de José Emilio Pacheco. El enfoque contempla el razonamiento al argumentar sobre interpretaciones, informaciones no concluyentes y valoraciones de la postura asumida debido a distintas explicaciones. La metodología aporta categorías sobre intencionalidad argumentativa, textualidad, contenidos, representaciones textuales de los estudiantes y la contraposición dialógica de posturas. Los resultados muestran las estrategias de redacción argumentativa basada en suposiciones y los intentos por mejorarla en una segunda versión para fortalecer la postura propia como la más convincente. Las conclusiones destacan la diversidad de estrategias argumentativas y de textualidad al tratar de convencer sobre la postura asumida al tratar de dar sentido al final de la novela.
Relação entre tabagismo e a educação médica
Authors: Azevedo Renata Cruz Soares de , Maia João Maurício Castaldelli
Published: September 2023

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Diagnóstico e tratamento da demência
Authors: Perroco Tíbor Rilho , Rodrigues Valeska Marinho
Published: September 2023

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Efficacy of German chamomile mouthrinse on plaque, gingivitis, periodontal pockets and calculus in man
Authors: K. Younis Shaymaa , D. Salman Faraed
Published: September 2023

The aims of this study werc to evaluate the effectiveness of German chamomile extract as a mouthrinse on the development of plague, gingivitis, pathological pockets and calculus in man to determine whether it can provide any benefit without the addition of other additives.Fifty adult volunteers participated in this controlied single blind cross-over study. The subjects used either German Chamomile or a chlorhexidine mouthrinse for 1 minute twice daily during eight weeks period. 2 weeks interval between each visit for motivation and reinforcement of application of the material Four applied indices (plaque and gingival indices by Loe and Silness), CPITN index by Ainamo and calculus index by Ramfjord were recorded at baseline, after each experimental period and at the last visit. The mean reduction in plaque. gingival and periodontal pocket depths were determined by using paired Z-test between each visit at P< 0.01 significantly lower for GC than for CHX mouthrinse. While for calculus index there was significant increase between each visit at P< 0.05 using paired Z-test and for all visits using repeated measures ~~ F-test at P <0.01.Using GC mouthrinse in a percentage of 1:4 appears to offer benefit in plaque, gingival, pocket depth reductions but with significant adverse increase in calculus index.
Otitis externa and the use of different antibiotics
Authors: Abdelhameed Buthaina , Sulaiman Erzaiq Zainab , H. Alanee Ahmed
Published: September 2023

A descriptive study , microbiological and pharmacological study was done on hildren with otitis externa 10 years of age and less attending the pediatrics and the Ear Nose and Throat department at the Tikrit Teaching hospitals during the period from 1st of August to 2007 to the last of February 2008. The aim of this study is to evaluate the response of bacteria causing otitis externa to the newly used antibiotics as compared with other old drugs. The total number of cases were 27 cases, males were 21 (77.8% ) while the rest were females, 6 cases (22.2% ). Most of the study cases were between the age of 5-10 years 22 cases (81.5%) .Most of the study cases were from the rural areas 18 cases (66.7%) . Chronic otitis externa is the commonest form of disease in the study cases 25 cases (92.6%) .Most of the study cases have nilateral OE 22 cases (81.5%). Most ofthe cases have infection at the auricle in both male and females, 13 cases (48.1%) and 5 cases (18.5%) respectively. Most ofthe study cases have onset of the disease during summer time , 21 cases (77. 8% ). Most of the study cases had history of swimming 19 cases (70.4% ). All the study cases had history of auricular pain 27 cases (100%), followed by feeling of itching in 16 cases (59.3% All the study cases have tenderness of the external ears specially on moving the pinna 27 cases (100%), followed by swelling of the pinna 16 cases (59.3% ).Staph aureus was the commonest microorganism encountered 18 cases ( 66.7%) followed by pseudomonas Aeruginosa 2 cases (7.4% ). No growth was found in 6 cases (22.2% ). Regarding staph aureus, there is significant response to both erythromycin and to the ciprofloxacin , 18 cases ( 1 00%) and 17 cases (94.4% ) respectively. Regarding the pseudomonas , only the ciprofloxacin and norfloxacin shows response 2 cases for each (100%).the study concludes that the use ofnew regime in the treatment of otitis
Effect or different concentrations of acidic olive leaves extractmouth rinse on plaque, gingivitis and periodontal pockets onadults
Authors: K. Younis Shaymaa , D. Salman Faraed
Published: September 2023

Aims: The aims of this study were to evaluate the effectiveness of olive leaves extract mouthrinse on the development of plaque, gingivitis, periodontal pockets in different concentrations as pure extract 50%, apple cider vinegar (ACV) extract rinse 50%, ACV + olive leave extract (OLE) 15% in acidic medium, 20% ACV + OLE mouthrinse compared with the ideal standard control mouthrinse chlorhexidine (CHX) 0.2%. Fifty adult volunteers participated in this controlled single blind cross— over study, 10 subjects for each group, one control and four experimental groups with different concentrations of the rinse for | minute twice daily during 8 weeks period, 2 weeks interval between each visit for motivation and reinforcement of application of the material. Three applied indices (plaque and gingival indices by Loe and Silness), CPITN index by Ainamo recorded at baseline, after each experimental period and at the last visit, then examining the biological activity of the material in the laboratory. It had been found that materials were effective on the three applied indices with significant percentage reduction (for OLE 50%, ACV 50%) at p < 0.001 using unpaired Z-test, and at p < 0.001, p < 0.0! for OLE + ACV 51%, OLE + ACV 20% respectively using unpaired Z-test except for some visits for the two materials. Percentage reductions for the four applied concentrations were greatest for OLE + ACV 20%, OLE ~ ACV 15%, ACV, OLE respectively for the three applied indices with significant differences at p < 0.05 using repeated measures analysis of variance and Duncan test. Using OLE mouthrinse in different acidic concentrations offer benefit in plaque. gingival, periodontal pocket depth reductions, but it is much lower than that of CHX 0.2% mouthrinsc.
Transmission of Escherichia coli 0 l57: H7 to cattle by house flies
Authors: Mustapha Muhammed Burhan
Published: September 2023

1 he aims of this study were to determin the prevalence of and characteriLe E coli0157. H7 &'>OCiated with houseflies. Musca domestica were collected from differentsites on a canle fann o•er a S- month period and processed individuaaly for E. coli0157: H7 isolation and quanitication. E. coli T 0157 counts ranged from 5• 106-3"107 CI'U among posit ive houseflies . Microobial resistance of five differentantimicrobial; agents revealed that all the E. coli 0157: H7 isolates from all i~olateswere resi,tant to one or more of antimocrobial agents
Enzyme lrnmtmoassay Technique for the Determination ofHormones inHumanSemm
Authors: Alwaan Jassim Ayub , Hassan Kharnoob Hussian
Published: September 2023

Enzyme Linked Immunosorbant Assay (ELISA) is two immunological steps sandwich type assay. In the first step the hormone is captured by a monoclonal antibody bound to the wells of a micrometer plate. In the second step a biotinylated monoclonal antibody is added with streptavidin -peroxidase conjugate. The biotinylated antibody binds to the solid phase antibody complex and, in turn, binds the conjugate. After incubation, the wells are washed and the antigen complex bound to the well detected by addition of chromogenic substrate. The intensity of the coloration is proportional to the hormone concentration in the sample. ELISA technique for quantitative determination of Tri-iodothyroxine (13). Tetra-iodothyroxine (Ty). thyroid Stimulating Hormone (ISH). prolactin (Prol). Luteinizing hormone (111), Follicle Stimulating Hormone (FSH) and (Testo.) concentration was used. In present work the minimum detectable centrations (MDC) of | ones by this technique were estimated to be:

The study was conducted in Al-Khadmia Teaching Hospital from November 2006 to June 2007 and aimed recovery, precision. accuracy and minimum detection limit of analytical technique ELISA for the determination of hormones in (35) samples of human serum.
Screening Study for Determination Serum Calcium andPhosphorus Levels in Renal failure Patients in Tikrit City
Authors: Ahmed Hassan Hassan
Published: September 2023

The present study was designed to determine the calcium and phosphorus levels in patients (N=30) suffering form renal failure in (Al-Qadissia hospital- Tikrit city) and comparing with healthy volunteers. This method is based on using specific kits for these measurements to calculate the concentration of these two elements in (mg/di) in patients and healthy volunteers with (p< 0.05) and show good correlation between higher level of calcium and lower level of phosphorus in serum .
Differential Study of Antimicrobial Activity of Vancomycin and Teicoplanin (Targocid) against Strains of Staphylococcus aureus and Streptococci sp.
Authors: Ali Hasan Waseem
Published: September 2023

The glycopeptide antibiotics vancomycin and teicoplanin (targocid) are widely used in the treatment of infections caused by gram positive bacteria. Vancomyc inhibits both transglycosylation and transpeptidation reaction during peptidoglycan assembly, targocid inhibits peptidoglycan polymerization, resulting in inhibition of bacterial cell wall synthesis and cell death. In this study twenty strains of streptococcus pyogenes and streptococcus pneumoniae and twenty five strains of staphylococcus aureus were collected from different infections. MI Cs and MBCs of vancomycin and targocid were determined against the bacterial strains, the MICs of vancomycin for the streptococcus strains were 4-8 µg /ml compared with 8-16 µg/ml for targocid and MI Cs of targocid for staphylococcus aureus were 4-16 µg/ml MBC for the same strains were 8-32 µg/ml. the conclusion of this study was that targocid was less active than vancomycin against staphylococci but equal or more active against streptococci specifically it presents excellent in vitro activity against streptococcus pneumonia strains.
Prevalence of Breast Feeding in the Locality of IBN- Al- Baldy Hospital
Authors: Hasan Dhary Al-Jumaily Ali
Published: September 2023

One hundred mothers of children below two years of age were interviewed regarding some socioeconomic and health factors affecting breast-feeding in the area seived by IBN-AL-balady Hospital in Baghdad at august 200?. The study revealed that 57Yo of the mothers were exclusively breast-feeding their children insufficient milk was the most common mentioned reason (57.7%) for starting bottle feeding.A negative association was observed between breast -feeding and education of the mothers" Illiterate mothers were more likely to breast;-feed their infants (70%) than educated mothers (57.1 %) .More governmental and social support is needed to promote and protect breast feeding in our society.
Phytochemical analysis and antibacterial activity of some medicinal plantsagainst methicillin-resistant Staphylococcus aureues
Authors: N. Darogha Suhaila
Published: September 2023

The objective of this study is, first to report the prevalence of methicillin resistant Staphylococcus aureues (MRSA) infections and their antibiotic susceptibility patterns in Teaching and Emergency Hospital in Erbil city, and second to screen four medicinal plants: Eucalyptus globulus, Anethum graveolens, Prosopis farcta and Ficus carica (both aqueous extract and ethanolic extract) for potential antibacterial activity against MRSA isolates , then screening the phytochemical properties of these plants. Out of total 110 strains of Staphylococcus aureues isolated from different clinical specimens, 15 (13 .6%) were found to be methicillin resistant. All MRSA strains were found to be resistant to penicillin and gentamycin while 86.66% were resistant to cephalothin ,doxycyclin and tobramycin. However, no strains were resistant to vancomycin. Determination of minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values were performed using micro broth dilution method. The MIC/MBC of aqueo.us and ethanolic extracts of E. globulus against MRSA isolates were 25/12.5 mg/ml and 6.25/3.125 mg/ml respectively, while of P. farcta were 100/25 mg/ml and 25/12.5 mg/ml respectively. The results also revealed that extracts of F. carcia were inactive against MRSA. Preliminary phytochemical analysis revealed the presence of tannins and phenols in almost all the crude extracts followed by alkaloids and resins, while the glycosides was not detected in any extracts of the four plants tested.