bluuebunny/crossref_metadata_2025 huggingface dataset:
Researching the Impact of Parameters of the Developed Routing Models on Network Performance
Authors: Alhihi Mohammad , Attar Hani , Samour Mohammad , Akulynichev Artem
Published: June 2017

Nowadays, it is hard to imagine work without applying the principle of computer networks, and every day the requirement for high-quality network maintenance is increasing. In order to have a high-quality network; always optimize QoS through the optimization of routing protocols is required. In this paper, the scientific task of optimizing routing processes in hybrid telecommunication networks with guaranteed quality of service is solved by developing models and methods of adaptive routing. To develop methods, a system of Telecommunications network (TN) mathematical models was constructed at the levels of its morphological and functional descriptions. We used a weighted oriented graph as a structural model. Formalization of the main indicators of the network operation efficiency is carried out, which are the network performance (or its derivatives – relative and normalized performances) and indicators of the degree of use of network resources – buffer memory capacities of nodes and bandwidth of the transmission paths. In this paper, an experimental study of the developed models and routing methods was carried out in order to verify their adequacy, evaluate the effectiveness, and develop practical recommendations. The scheme of experiment, focusing on the investigation of processes occurring in the network while solving routing tasks (data gathering, RT processing, distribution, and implementation), is proposed.
The Impact of Social and Digital Medias on Senegalese Society
Authors: Sall Ousmane
Published: June 2017

West African countries especially Senegal, have a very rich history of written and oral communication based on their culture and traditions. Today, Senegal is inescapable about the adoption and use of new technologies in Africa. Senegal experienced a boom of cell phones users over the past 5 years in 2012 for example, we noticed “88% mobile subscriptions” compared with “46% mobile subscriptions in 2008” {world bank,2013}. That explains mobile phones are no more to make a call or to send a text message but also to interact with people around and entertain. In fact, digital communication is expanding in all Senegalese spheres like the workplace, school, universities... in the latter half of the 20th century before the explosion of social media, people only depended on old media like TV, Radio, Newspapers… to get informed. For this study, we are going to focus on how social media are impacting economically and politically on Senegalese society and how young people are managing the transition between traditional media and new media.
Characteristics of a Spherical Seat TPJB With Four Methods of Directed Lubrication—Part II: Rotordynamic Performance
Authors: Coghlan David M. , Childs Dara W.
Published: June 2017

Measured and predicted rotordynamic characteristics are presented for a four-pad, spherical-seat, tilting-pad journal bearing (TPJB) with 0.5 pivot offset, 0.6 L/D, 101.6 mm nominal diameter, and 0.3 preload in the load-between-pivots orientation. One bearing is tested four separate times in the following four different lubrication configurations: (1) flooded single-orifice (SO) at the bearing shell, (2) evacuated leading edge groove (LEG), (3) evacuated spray-bar blocker (SBB), and (4) evacuated spray-bar (SB). The same set of pads is used for every test to maintain clearance and preload; each method of lubrication is added as an assembly to the bearing. Test conditions include surface speeds and unit loads up to 85 m/s and 2.9 MPa, respectively. Dynamic data includes four sets (one set for each bearing configuration) of direct and cross-coupled rotordynamic coefficients derived from measurements and fit to a frequency-independent stiffness-damping-mass (KCM) matrix model. The pivot stiffness (pad and pivot in series) is measured and incorporated into predictions.
Emergence of a Staphylococcus aureus Clone Resistant to Mupirocin and Fusidic Acid Carrying Exotoxin Genes and Causing Mainly Skin Infections
Authors: Doudoulakakis Anastassios , Spiliopoulou Iris , Spyridis Nikolaos , Giormezis Nikolaos , Kopsidas John , Militsopoulou Maria , Lebessi Evangelia , Tsolia Maria
Published: June 2017

Skin and soft tissue infections (SSTIs) caused by mupirocin-resistant
Staphylococcus aureus
strains have recently increased in number in our settings. We sought to evaluate the characteristics of these cases over a 43-month period. Data for all community-acquired staphylococcal infections caused by mupirocin-resistant strains were retrospectively reviewed. Genes encoding products producing high-level resistance (HLR) to mupirocin (
mupA
), fusidic acid resistance (
fusB
), resistance to macrolides and lincosamides (
ermC
and
ermA
), Panton-Valentine leukocidin (PVL) (
lukS/lukF
-PV), exfoliative toxins (
eta
and
etb
), and fibronectin binding protein A (
fnbA
) were investigated by PCRs in 102 selected preserved strains. Genotyping was performed by SCC
mec
and
agr
typing, whereas clonality was determined by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). A total of 437 cases among 2,137 staphylococcal infections were recorded in 2013 to 2016; they were all SSTIs with the exception of 1 case of primary bacteremia. Impetigo was the predominant clinical entity (371 cases [84.9%]), followed by staphylococcal scalded skin syndrome (21 cases [4.8%]), and there were no abscesses. The number of infections detected annually increased during the study years. All except 3 isolates were methicillin susceptible. The rates of HLR to mupirocin and constitutive resistance to clindamycin were 99% and 20.1%, respectively. Among the 102 tested strains, 100 (98%) were
mupA
positive and 97 (95%) were
fusB
positive, 26/27 clindamycin-resistant strains (96.3%) were
ermA
positive, 83 strains (81.4%) were
lukS/lukF
positive, 95 (93%) carried both
eta
and
etb
genes, and 99 (97%) were
fnbA
positive. Genotyping of methicillin-sensitive
S. aureus
(MSSA) strains revealed that 96/99 (96.7%) belonged to one main pulsotype, pulsotype 1, classified as sequence type 121 (ST121). The emergence of a single MSSA clone (ST121) causing impetigo was documented. Resistance to topical antimicrobials and a rich toxinogenic profile confer to this clone adaptability for spread in the community.
Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N
6
-Adenosine Methylation To Promote Lytic Replication
Authors: Ye Fengchun , Chen E. Ricky , Nilsen Timothy W.
Published: June 2017

N
6
-adenosine methylation (m
6
A) is the most common posttranscriptional RNA modification in mammalian cells. We found that most transcripts encoded by the Kaposi's sarcoma-associated herpesvirus (KSHV) genome undergo m
6
A modification. The levels of m
6
A-modified mRNAs increased substantially upon stimulation for lytic replication. The blockage of m
6
A inhibited splicing of the pre-mRNA encoding the replication transcription activator (RTA), a key KSHV lytic switch protein, and halted viral lytic replication. We identified several m
6
A sites in RTA pre-mRNA crucial for splicing through interactions with YTH domain containing 1 (YTHDC1), an m
6
A nuclear reader protein, in conjunction with serine/arginine-rich splicing factor 3 (SRSF3) and SRSF10. Interestingly, RTA induced m
6
A and enhanced its own pre-mRNA splicing. Our results not only demonstrate an essential role of m
6
A in regulating RTA pre-mRNA splicing but also suggest that KSHV has evolved a mechanism to manipulate the host m
6
A machinery to its advantage in promoting lytic replication.

IMPORTANCE
KSHV productive lytic replication plays a pivotal role in the initiation and progression of Kaposi's sarcoma tumors. Previous studies suggested that the KSHV switch from latency to lytic replication is primarily controlled at the chromatin level through histone and DNA modifications. The present work reports for the first time that KSHV genome-encoded mRNAs undergo m
6
A modification, which represents a new mechanism at the posttranscriptional level in the control of viral replication.
Use of a Recombinant Gamma-2 Herpesvirus Vaccine Vector against Dengue Virus in Rhesus Monkeys
Authors: Bischof Georg F. , Magnani Diogo M. , Ricciardi Michael , Shin Young C. , Domingues Aline , Bailey Varian K. , Gonzalez-Nieto Lucas , Rakasz Eva G. , Watkins David I. , Desrosiers Ronald C.
Published: June 2017

Research on vaccine approaches that can provide long-term protection against dengue virus infection is needed. Here we describe the construction, immunogenicity, and preliminary information on the protective capacity of recombinant, replication-competent rhesus monkey rhadinovirus (RRV), a persisting herpesvirus. One RRV construct expressed nonstructural protein 5 (NS5), while a second recombinant expressed a soluble variant of the E protein (E85) of dengue virus 2 (DENV2). Four rhesus macaques received a single vaccination with a mixture of both recombinant RRVs and were subsequently challenged 19 weeks later with 1 × 105PFU of DENV2. During the vaccine phase, plasma of all vaccinated monkeys showed neutralizing activity against DENV2. Cellular immune responses against NS5 were also elicited, as evidenced by major histocompatibility complex class I (MHC-I) tetramer staining in the one vaccinated monkey that wasMamu-A*01positive. Unlike two of two unvaccinated controls, two of the four vaccinated monkeys showed no detectable viral RNA sequences in plasma after challenge. One of these two monkeys also showed no anamnestic increases in antibody levels following challenge and thus appeared to be protected against the acquisition of DENV2 following high-dose challenge. Continued study will be needed to evaluate the performance of herpesviral and other persisting vectors for achieving long-term protection against dengue virus infection.

IMPORTANCEContinuing studies of vaccine approaches against dengue virus (DENV) infection are warranted, particularly ones that may provide long-term immunity against all four serotypes. Here we investigated whether recombinant rhesus monkey rhadinovirus (RRV) could be used as a vaccine against DENV2 infection in rhesus monkeys. Upon vaccination, all animals generated antibodies capable of neutralizing DENV2. Two of four vaccinated monkeys showed no detectable viral RNA after subsequent high-dose DENV2 challenge at 19 weeks postvaccination. Furthermore, one of these vaccinated monkeys appeared to be protected against the acquisition of DENV2 infection on the basis of undetectable viral loads and the lack of an anamnestic antibody response. These findings underscore the potential utility of recombinant herpesviruses as vaccine vectors.
Modafinil in schizophrenia: is the risk worth taking?
Authors: Neto Daniel , Spínola Carla , Gago Joaquim
Published: June 2017

Schizophrenia is a severe mental disorder characterised by positive and negative symptoms. Negative symptoms are difficult to treat and there is no specific treatment. In small trials, modafinil has been studied in association with antipsychotic treatment. We present three cases of its use; two have developed positive symptoms and one developed renal impairment. Further studies are needed to assess its usefulness in schizophrenia and safety in this group of patients.
Isolated gastric sarcoidosis: a rare entity
Authors: Patel Ronak Vashi , Winter Rachel W , Chan Walter W , Sparks Jeffrey A
Published: June 2017

We present a case of isolated granulomatous gastritis in a 21-year-old woman. Initial symptoms included nausea, vomiting and inability to tolerate oral intake. An upper oesophagogastroduodenoscopy revealed nodular and thickened mucosa with histological findings of granulomatous gastritis. Infectious, inflammatory and malignant causes were excluded prior to making a diagnosis of gastric sarcoidosis.
The influence of multisite pain and psychological comorbidity on prognosis of chronic low back pain: longitudinal data from the Norwegian HUNT Study
Authors: Nordstoga Anne Lovise , Nilsen Tom Ivar Lund , Vasseljen Ottar , Unsgaard-Tøndel Monica , Mork Paul Jarle
Published: June 2017

Objectives

This study aimed to investigate the prospective influence of multisite pain, depression, anxiety, self-rated health and pain-related disability on recovery from chronic low back pain (LBP).

Setting

The data is derived from the second (1995–1997) and third (2006–2008) wave of the Nord-Trøndelag Health Study (HUNT) in Norway.

Participants

The study population comprises 4484 women and 3039 men in the Norwegian HUNT Study who reported chronic LBP at baseline in 1995–1997.

Primary outcome measures

The primary outcome was recovery from chronic LBP at the 11-year follow-up. Persons not reporting pain and/or stiffness for at least three consecutive months during the last year were defined as recovered. A Poisson regression model was used to estimate adjusted risk ratios (RRs) with 95% CIs.

Results

At follow-up, 1822 (40.6%) women and 1578 (51.9%) men reported recovery from chronic LBP. The probability of recovery was inversely associated with number of pain sites (P-trend<0.001). Compared with reporting 2–3 pain sites, persons with only LBP had a slightly higher probability of recovery (RR 1.10, 95% CI 0.98 to 1.22 in women and RR 1.10, 95% CI 1.01 to 1.21 in men), whereas people reporting 6–9 pain sites had substantially lower probability of recovery (RR 0.58, 95% CI 0.52 to 0.63 in women and RR 0.70, 95% CI 0.63 to 0.79 in men). Poor/not so good self-rated general health, symptoms of anxiety and depression, and pain-related disability in work and leisure were all associated with reduced probability of recovery, but there was no statistical interaction between multisite pain and these comorbidities.

Conclusions

Increasing number of pain sites was inversely associated with recovery from chronic LBP. In addition, factors such as poor self-rated health, psychological symptoms and pain-related disability may further reduce the probability of recovery from chronic LBP.
Update on infectious bovine rhinotracheitis
Authors: Nettleton Peter , Russell George
Published: June 2017

Infectious bovine rhinotracheitis (IBR) is the major disease caused by bovine herpesvirus 1 (BoHV‐1), an important pathogen of cattle. Being an alphaherpesvirus, the virus establishes a lifelong latent infection in sensory nerve ganglia following primary infection. Latent virus can be reactivated by various stressful stimuli, and subsequent re‐excretion of the infectious virus maintains infection within a herd. BoHV‐1 is important to all cattle farmers because of the range of diseases it can cause and because infection can be a barrier to international trade; therefore, every cattle herd health plan should contain a strategy for its control. A feature of infections caused by the virus is their variability – from severe and fatal to mild and even subclinical – and outcomes are dependent on combinations of viral, host and environmental factors. An accurate diagnosis is crucial and control of disease is feasible given the excellent diagnostic tools, understanding of the biology of the virus and the availability of effective IBR marker vaccines. Eradication of the virus is also possible over a longer period of time. This article describes the virus and the diseases it causes, and then discusses options for diagnosis, vaccination, control and eradication, and possible priorities for further study.
Theoretical calculation of electron density and temperature in the edge of tokamak
Authors: Asif Muhammad , Asif Anila
Published: June 2017

In this work, we use a method based on the concept of particle confinement time [Formula: see text] uniqueness to calculate the electron density and temperature in ohmically heated, edge plasma of the Hefei tokamak-7. Here, with the help of the data taken from Johnson and Hinnov’s table, we have done an extensive work to find electron densities and temperatures that satisfy the [Formula: see text] uniqueness to evaluate the temporal evolution of electron density [Formula: see text] and temperature [Formula: see text]. The results are in good agreement as measured from the Langmuir probe array in previous works.
A proof of the weak gravity conjecture
Authors: Hod Shahar
Published: June 2017

The weak gravity conjecture suggests that, in a self-consistent theory of quantum gravity, the strength of gravity is bounded from above by the strengths of the various gauge forces in the theory. In particular, this intriguing conjecture asserts that in a theory describing a [Formula: see text] gauge field coupled consistently to gravity, there must exist a particle whose proper mass is bounded (in Planck units) by its charge: [Formula: see text]. This beautiful and remarkably compact conjecture has attracted the attention of physicists and mathematicians over the last decade. It should be emphasized, however, that despite the fact that there are numerous examples from field theory and string theory that support the conjecture, we still lack a general proof of its validity. In the present paper, we prove that the weak gravity conjecture (and, in particular, the mass–charge upper bound [Formula: see text]) can be inferred directly from Bekenstein’s generalized second law of thermodynamics, a law which is widely believed to reflect a fundamental aspect of the elusive theory of quantum gravity.
Stochastic Lévy differential operators and Yang–Mills equations
Authors: Volkov Boris O.
Published: June 2017

The relationship between the Yang–Mills equations and the stochastic analogue of Lévy differential operators is studied. The value of the stochastic Lévy–Laplacian is found by means of Cèsaro averaging of directional derivatives on the stochastic parallel transport. It is shown that the Yang–Mills equations and the Lévy–Laplace equation for such Laplacian are not equivalent in contrast to the deterministic case. An equation equivalent to the Yang–Mills equations is obtained. The equation contains the Lévy divergence. It is proved that the Yang–Mills action functional can be represented as an infinite-dimensional analogue of the Direchlet functional of a chiral field. This analogue is also derived using Cèsaro averaging.
d-dimensional orthogonal polynomials: Commutator theorem and other results
Authors: Accardi Luigi , Dhahri Abdallah
Published: June 2017

We give new and simplified proofs of three basic theorems in the theory of orthogonal polynomials associated to a classical, [Formula: see text]-valued random variable [Formula: see text] with all moments, namely: (1) The characterization of [Formula: see text] in terms of commutators among the creation–annihilation–preservation (CAP) operators in its quantum decomposition. (2) The characterization, in terms of the same objects, of the fact that the distribution of [Formula: see text] is a product measure. (3) The equivalence of the symmetry of [Formula: see text] with the vanishing of the associated preservation operator.

Our new formulation of these results allows one to obtain a stronger form of the above statements.
Tripartite Bell-type inequalities for quantum coherence and skew information
Authors: Qiu Liang , Pan Fei , Liu Zhi
Published: June 2017

We construct the tripartite Bell-type inequalities of product states for [Formula: see text]-norm of coherence, relative entropy of coherence and skew information. We give examples of three-qubit entangled states that violate these inequalities. Particularly, the tripartite Bell-type inequality for relative entropy of coherence is always violated by the W class pure or mixed states as well as the GHZ class pure or mixed states, being used as entanglement witness.
μNeurocircuitry: Establishing in vitro models of neurocircuits with human neurons
Authors: Fantuzzo Joseph A. , De Filippis Lidia , McGowan Heather , Yang Nan , Ng Yi-Han , Halikere Apoorva , Liu Jing-Jing , Hart Ronald P. , Wernig Marius , Zahn Jeffrey D. , Pang Zhiping P.
Published: June 2017

Neurocircuits in the human brain govern complex behavior and involve connections from many different neuronal subtypes from different brain regions. Recent advances in stem cell biology have enabled the derivation of patient-specific human neuronal cells of various subtypes for the study of neuronal function and disease pathology. Nevertheless, one persistent challenge using these human-derived neurons is the ability to reconstruct models of human brain circuitry. To overcome this obstacle, we have developed a compartmentalized microfluidic device, which allows for spatial separation of cell bodies of different human-derived neuronal subtypes (excitatory, inhibitory and dopaminergic) but is permissive to the spreading of projecting processes. Induced neurons (iNs) cultured in the device expressed pan-neuronal markers and subtype specific markers. Morphologically, we demonstrate defined synaptic contacts between selected neuronal subtypes by synapsin staining. Functionally, we show that excitatory neuronal stimulation evoked excitatory postsynaptic current responses in the neurons cultured in a separate chamber.
Pricing spread options by generalized bivariate edgeworth expansion
Authors: Kao Edward P. C. , Xie Weiwei
Published: June 2017

A spread option is a contingent claim whose underlying is the price difference between two assets. For a call, the holder of the option receives the difference, if positive, between the price difference and the strike price. Otherwise, the holder receives nothing. Spread options trade in large volume in financial, fixed-income, commodity, and energy industries. It is well known that pricing of spread options does not admit closed-form solutions even under a geometric Brownian motion paradigm. When price dynamics experience stochastic volatilities and/or jumps, the valuation process becomes more challenging. Following the seminal work of Jarrow and Judd, we propose the use of Edgeworth expansion to approximate the call price. In the spirit of Pearson, we reduce the cumbersome computation inherent in Edgeworth expansion to single numerical integrations. For an arbitrary bivariate price process, we show that once its product cumulants are available, either by virtue of the structural properties of the underlying processes or by empirical estimation using market data, the approach enables analysts to approximate the call price easily. Specifically, the call prices so estimated capture the correlation, skewness, and kurtosis of the two underlying price processes. As such, the approach is useful for approximate valuations based on Lévy-based models.
Synovial Sarcoma of the Head and Neck: A Single Institution Review
Authors: Gopalakrishnan Vancheswaran , Amini Behrang , Wagner Michael J. , Nowell Erica N. , Lazar Alexander J. , Lin Patrick P. , Benjamin Robert S. , Araujo Dejka M.
Published: June 2017

Background. The prognosis and clinical characteristics of head and neck synovial sarcomas (HNSS) are unclear. Herein, we present an update using a cohort of patients treated at our institution.Methods. We performed a retrospective chart review of 44 patients diagnosed with primary HNSS between March 1990 and June 2012. Overall survival (OS) and progression-free survival (PFS) curves were estimated and hazard ratios (HRs) were calculated.Results. The entire cohort’s median PFS was 4.6 years, and 20 of the 44 (45%) patients developed either local or distant recurrence. Tumor size ≥ 5 cm (p=0.008, HR = 4.69; 95% CI = 1.34–16.38) and a primary presentation in the soft tissues of the neck (p=0.04, HR = 2.41; 95% CI = 1.003–5.82) were associated with significantly worse PFS. The OS and PFS of patients who received definitive local therapy versus those who received additional adjuvant systemic therapy did not differ significantly.Conclusion. Despite the treatment challenges associated with HNSS, our cohort of patients had a better prognosis than one might expect in this unfavorable anatomical location. Our findings suggest that tumor size and site are predictive of PFS and that wide surgical excision is of vital importance, since traditional cytotoxic chemotherapy has limited efficacy at this site.
An Objective Train Timetabling Quality Evaluation Method
Authors: Jiang Feng , Yu Da-ben , Ni Shao-quan
Published: June 2017

The train timetable dominates the rail traffic organization. The timetabling quality should be evaluated to check the work skill of train timetable managers. The values of existing timetable evaluation indexes vary with infrastructure features and traffic flow; therefore, they are not comparable in fact. Furthermore, subjective inputs like expert scores are involved in evaluation; this will lead to unreliable results because the experts may have different opinions. To overcome these shortages, we propose a relative train path efficiency index by taking the train paths as production units. Each unit consumes some transport resources and produces some feedback outputs. A DEA model is applied to compute the train path efficiency. Two statistical functions of train path efficiency are used to evaluate the timetabling quality. We verify our method with real‐world timetables. First, we use the Shibantan‐to‐Xinqiao line timetable to test the relative feature of the index proposed, and the results show that the train path efficiency value is relative and can reflect whether the stops are evenly distributed or not. Second, we evaluate the timetabling quality of another two timetables of the Qingdao‐to‐Jinan line with different traffic flows, and the results show that, compared with the 2012 timetable, the timetabling quality decreased in 2013.
Multiplicity Results for Positive Solutions to Differential Systems of Singular Coupled Integral Boundary Value Problems
Authors: Cui Yujun
Published: June 2017

By constructing a special cone and using a fixed‐point theorem in cone, this paper investigates the existence of multiple solutions of coupled integral boundary value problems for a nonlinear singular differential system.
Hesitant Anti‐Fuzzy Soft Set in BCK‐Algebras
Authors: Alshehri Halimah , Alshehri Noura
Published: June 2017

We introduce the notions of hesitant anti‐fuzzy soft set (subalgebras and ideals) and provide relation between them. However, we study new types of hesitant anti‐fuzzy soft ideals (implicative, positive implicative, and commutative). Also, we stated and proved some theorems which determine the relationship between these notions.
Robotics in Lower-Limb Rehabilitation after Stroke
Authors: Zhang Xue , Yue Zan , Wang Jing
Published: June 2017

With the increase in the elderly, stroke has become a common disease, often leading to motor dysfunction and even permanent disability. Lower-limb rehabilitation robots can help patients to carry out reasonable and effective training to improve the motor function of paralyzed extremity. In this paper, the developments of lower-limb rehabilitation robots in the past decades are reviewed. Specifically, we provide a classification, a comparison, and a design overview of the driving modes, training paradigm, and control strategy of the lower-limb rehabilitation robots in the reviewed literature. A brief review on the gait detection technology of lower-limb rehabilitation robots is also presented. Finally, we discuss the future directions of the lower-limb rehabilitation robots.
Study of Carbonaceous and Nitrogenous Pollutant Removal Efficiencies in a Hybrid Membrane Bioreactor
Authors: Ruys Victor S. , Zerari Kamel , Seyssiecq Isabelle , Roche Nicolas
Published: June 2017

A hybrid membrane bioreactor (HMBR) comprises activated sludge (free biomass), a biofilm (supported biomass), and a membrane separation. A laboratory pilot-scale HMBR was operated for seven months with high organic loads of both carbonic and nitrogen pollutants. Several experiments were conducted to investigate the influence of the height of the packing bed (27 cm, 50 cm, and 0 cm) and the effect of the concentration of dissolved oxygen (DO) on the organic removal rate, total nitrogen removal rate (TN), and ammonium removal. The organic removal rate was always >95% and mostly >98%. The NH4+-N and TN removal rates were directly related to DO. NH4+-N removal rate reached 100% and was mostly >99% with a concentration of DO > 0.1 mg/L, whereas the NO3--N removal rate was differentially affected depending on the level of DO. The removal rate increased when the concentration of DO was optimal for simultaneous nitrification and denitrification, which was between 0.1 and 0.5 mg/l, and the TN removal rate was consequently high. The removal rate decreased when DO was high and denitrification was consequently low thereby reducing the TN removal rate. This implies that high levels of DO (>1 mg/L) limit the denitrification process and low levels of DO (<0.1 mg/L) limit the nitrification process and hence total nitrogen removal in the bioreactor.
The Performance of Structure-Controller Coupled Systems Analysis Using Probabilistic Evaluation and Identification Model Approach
Authors: Kaloop Mosbeh R. , Hu Jong Wan , Bigdeli Yasser
Published: June 2017

This study evaluates the performance of passively controlled steel frame building under dynamic loads using time series analysis. A novel application is utilized for the time and frequency domains evaluation to analyze the behavior of controlling systems. In addition, the autoregressive moving average (ARMA) neural networks are employed to identify the performance of the controller system. Three passive vibration control devices are utilized in this study, namely, tuned mass damper (TMD), tuned liquid damper (TLD), and tuned liquid column damper (TLCD). The results show that the TMD control system is a more reliable controller than TLD and TLCD systems in terms of vibration mitigation. The probabilistic evaluation and identification model showed that the probability analysis and ARMA neural network model are suitable to evaluate and predict the response of coupled building-controller systems.
Significant Improvement Selected Mediators of Inflammation in Phenotypes of Women with PCOS after Reduction and Low GI Diet
Authors: Szczuko Małgorzata , Zapałowska-Chwyć Marta , Maciejewska Dominika , Drozd Arleta , Starczewski Andrzej , Stachowska Ewa
Published: June 2017

Many researchers suggest an increased risk of atherosclerosis in women with polycystic ovary syndrome. In the available literature, there are no studies on the mediators of inflammation in women with PCOS, especially after dietary intervention. Eicosanoids (HETE and HODE) were compared between the biochemical phenotypes of women with PCOS (normal and high androgens) and after the 3-month reduction diet. Eicosanoid profiles (9(S)-HODE, 13(S)-HODE, 5(S)-HETE, 12(S)-HETE, 15(S)-HETE, 5(S)-oxoETE, 16(R)-HETE, 16(S)-HETE and 5(S), 6(R)-lipoxin A4, 5(S), 6(R), 15(R)-lipoxin A4) were extracted from 0.5 ml of plasma using solid-phase extraction RP-18 SPE columns. The HPLC separations were performed on a 1260 liquid chromatograph. No significant differences were found in the concentration of analysed eicosanoids in phenotypes of women with PCOS. These women, however, have significantly lower concentration of inflammatory mediators than potentially healthy women from the control group. Dietary intervention leads to a significant (p<0.01) increase in the synthesis of proinflammatory mediators, reaching similar levels as in the control group. The development of inflammatory reaction in both phenotypes of women with PCOS is similar. The pathways for synthesis of proinflammatory mediators in women with PCOS are dormant, but can be stimulated through a reduction diet. Three-month period of lifestyle change may be too short to stimulate the pathways inhibiting inflammatory process.
Effect of Mouthwashes on Solubility and Sorption of Restorative Composites
Authors: Leal José Pereira , da Silva Jaqueline Damasceno , Leal Rafaelle Fernanda Melão , Oliveira-Júnior Carlos da Cunha , Prado Vera Lúcia Gomes , Vale Glauber Campos
Published: June 2017

Objective. Composites sorption and solubility can be precursors of several chemical and physical processes, which lead to deleterious effects on the polymer structure. This study evaluated the effect of mouthwashes on solubility and sorption of composite resins. Materials and Methods. Forty-two specimens of each evaluated composite (Filtek Bulk Fill Flow, Opallis Flow, Durafill VS, and Filtek Z350) were prepared and randomized into seven groups for each solution (mouth rinses with and without alcohol and distilled water) and stored for seven days. Solubility and sorption tests were performed according to ISO4049. Data were analyzed using 2-way-ANOVA followed by Tukey’s test for means comparison (α=0.05). In addition, paired t-test was performed to analyze the alcohol effect on the studied composite resin properties. Results. Listerine Cool Mint (containing alcohol in its composition) caused the greatest degree of sorption for all composites tested in comparison to other rinses, while for solubility this behavior was observed for Opallis Flow and Durafill VS composite resins (p<0.05). Regarding the composites, Opallis Flow showed the highest sorption and solubility values in general (p<0.05). Conclusion. Overall, the sorption and solubility of composites were higher in mouthwashes containing alcohol in its composition, with Opallis Flow being the most affected composite resin.
A Novel Ancient Coin-Like Fractal Multiband Antenna for Wireless Applications
Authors: Yu Zhen , Yu Jianguo , Ran Xiaoying , Zhu Chenhua
Published: June 2017

This study proposes a novel square-circle structure fractal multibroadband planar antenna, similar to an ancient Chinese coin-like structure, for second generation (2G), third generation (3G), fourth generation (4G), WLAN, and navigation wireless applications. The device is based on the principles and structural features of conventional monopole antenna elements, combined with the advantages of microstrip antennas and fractal geometry. A fractal method was presented for circular nested square slotted structures, similar to an ancient Chinese copper coin. The proposed antenna adapted five iterations on a fractal structure radiator, which covers more than ten mobile applications in three broad frequency bands with a bandwidth of 70% (1.43–2.97 GHz) for DCS1800, TD-SCDMA, WCDMA, CDMA2000, LTE33-41, Bluetooth, GPS (Global Positioning System), BDS (BeiDou Navigation Satellite System), GLONSS (Global Navigation Satellite System), GALILEO (Galileo Satellite Navigation System), and WLAN frequency bands, 16.32% (3.32–3.91 GHz) for LTE42, LTE43, and WiMAX frequency bands, and 10.92% (4.85–5.41 GHz) for WLAN frequency band. The proposed antenna was fabricated on a 1.6 mm thick G10/FR4 substrate with a dielectric constant of 4.4 and a size of 88.5 × 60 mm2. The measurement results reveal that the omnidirectional radiation patterns achieve a gain of 1.16–3.75 dBi and an efficiency of 40–72%. The good agreement between the measurement results and simulation validates the proposed design approach and satisfies the requirements for various wireless applications.
Difficult Laparoscopic Cholecystectomy and Trainees: Predictors and Results in an Academic Teaching Hospital
Authors: Atta Hussein M. , Mohamed Ashraf A. , Sewefy Alaa M. , Abdel-Fatah Abdel-Fatah S. , Mohammed Mohammed M. , Atiya Ahmed M.
Published: June 2017

Laparoscopic cholecystectomy (LC) is one of the first laparoscopic procedures performed by surgical trainees. This study aims to determine preoperative and/or intraoperative predictors of difficult LC and to compare complications of LC performed by trainees with that performed by trained surgeons. A cohort of 180 consecutive patients with cholelithiasis who underwent LC was analyzed. We used univariate and binary logistic regression analyses to predict factors associated with difficult LC. We compared the rate of complications of LCs performed by trainees and that performed by trained surgeons using Pearson’s chi-square test. Patients with impacted stone in the neck of the gallbladder (GB) (OR, 5.0; 95% CI, 1.59–15.77), with adhesions in the Triangle of Calot (OR, 2.9; 95% CI, 1.27–6.83), or with GB rupture (OR, 3.4; 95% CI, 1.02–11.41) were more likely to experience difficult LC. There was no difference between trainees and trained surgeons in the rate of cystic artery injury (p=.144) or GB rupture (p=.097). However, operative time of LCs performed by trained surgeons was significantly shorter (median, 45 min; IQR, 30–70 min) compared with the surgical trainees’ operative time (60 min; IQR, 50–90 min). Surgical trainees can perform difficult LC safely under supervision with no increase in complications albeit with mild increase in operative time.
Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional Methods
Authors: Yasemi Mahnaz , Heydarinasab Amir , Rahimi Masoud , Ardjmand Mehdi
Published: June 2017

Different methods of oleuropein extraction from olive leaf were investigated, including maceration, soxhlet, ultrasonic-assisted extraction, and microchannel. In current research, a response surface methodology (RSM) was used for prediction of the optimal values of parameters affecting the extraction of oleuropein through two methods of ultrasound and microchannel. Frequency (F), temperature (T), and power of ultrasound (P) were the parameters which were studied in ultrasound method, but in microchannel system effects of pH and temperature (T), volumetric flow rate ratio of two phases (VR), and contact time (CT) of two phases were optimized. UV detector device at 254 nm was used to recognize oleuropein through comparison of the retention time of the extracts with standard compound in chromatogram. The analysis of extracts was performed using HPLC. Optimum conditions for ultrasound were obtained as follows:F=80 kHz,T= 25°C, andP=100 w. Using these optimum conditions, the extraction of oleuropein was 81.29%. Amount of oleuropein extraction by microchannel method in optimum conditions was 96.29%, which was way more than other applied methods. Microchannel system as a continuous method has many advantages including low solvent consumption, being environment friendly, short time for extraction, and high efficiency.
Depressive Symptoms in Women with Gestational Diabetes Mellitus: The LINDA-Brazil Study
Authors: Damé Patrícia , Cherubini Kadhija , Goveia Pâmella , Pena Geórgia , Galliano Leony , Façanha Cristina , Nunes Maria Angélica
Published: June 2017

This study aimed to assess the frequency and severity of depressive symptoms and their relationship with sociodemographic characteristics in women with gestational diabetes mellitus (GDM) who participated in the LINDA-Brazil study. We conducted cross-sectional analyses of 820 women with GDM who were receiving prenatal care in the public health system. We conducted structured interviews to obtain clinical and sociodemographic information and applied the Edinburgh Postnatal Depression Scale (EPDS) to assess depressive symptoms. We classified the presence and severity of depressive symptoms using scores of ≥12 and ≥18, respectively. We used Poisson regression to estimate prevalence ratios (PR). Most of the women lived with a partner (88%), 50% were between 30 and 39 years old, 39% had finished high school, 39% had a family income of 1-2 minimum wages, and 47% were obese before their pregnancies. The presence of depressive symptoms was observed in 31% of the women, and severe depressive symptoms were observed in 10%; 8.3% reported self-harm intent. Lower parity and higher educational levels were associated with lower EPDS score. Depressive symptoms were common and frequently severe among women with GDM, indicating the need to consider this situation when treating such women, especially those who are more socially vulnerable. This trial is registered with NCT02327286, registered on 23 December 2014.
An Effective Algorithm for Globally Solving Sum of Linear Ratios Problems
Authors: Jiao Hongwei , Cai Lei , Hou Zhisong , Bai Chunyang
Published: June 2017

In this study, we propose an effective algorithm for globally solving the sum of linear ratios problems. Firstly, by introducing new variables, we transform the initial problem into an equivalent nonconvex programming problem. Secondly, by utilizing direct relaxation, the linear relaxation programming problem of the equivalent problem can be constructed. Thirdly, in order to improve the computational efficiency of the algorithm, an out space pruning technique is derived, which offers a possibility of pruning a large part of the out space region which does not contain the optimal solution of the equivalent problem. Fourthly, based on out space partition, by combining bounding technique and pruning technique, a new out space branch-and-bound algorithm for globally solving the sum of linear ratios problems (SLRP) is designed. Finally, numerical experimental results are presented to demonstrate both computational efficiency and solution quality of the proposed algorithm.
Off‐Design Behavior Analysis and Operating Curve Design of Marine Intercooled Gas Turbine
Authors: Ji Nian-kun , Li Shu-ying , Wang Zhi-tao , Zhao Ning-bo
Published: June 2017

The intercooled gas turbine obtained by adopting an indirect heat exchanger into an existing gas turbine is one of the candidates for developing high‐power marine power units. To simplify such a strong coupled nonlinear system reasonably, the feasibility and availability of qualifying equivalent effectiveness as the only parameter to evaluate the intercooler behavior are investigated. Regarding equivalent effectiveness as an additional degree of freedom, the steady state model of a marine intercooled gas turbine is developed and its off‐design performance is analyzed. With comprehensive considerations given to various phase missions of ships, operational flexibility, mechanical constraints, and thermal constraints, the operating curve of the intercooled gas turbine is optimized based on graphical method in three‐dimensional performance space. The resulting operating curve revealed that the control strategy at the steady state conditions for the intercooled gas turbine should be variable cycle control. The necessity of integration optimization design for gas turbine and intercooler is indicated and the modeling and analysis method developed in this paper should be beneficial to it.
The Effect of Dietary Supplements Containing Green Tea, Capsaicin and Ginger Extracts on Weight Loss and Metabolic Profiles in Overweight Women: A Randomized Double-Blind Placebo-Controlled Clinical Trial
Authors: Taghizadeh Mohsen , Farzin Narjes , Taheri Sara , Mahlouji Mahnaz , Akbari Hossein , Karamali Fatemeh , Asemi Zatollah
Published: June 2017

Background: This study was conducted to determine the effects of dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles among overweight women. Methods: This randomized double-blind placebo-controlled clinical trial was implemented among 50 overweight women. Participants were randomly divided into 2 groups. Group A received dietary supplements containing 125 mg green tea, 25 mg capsaicin and 50 mg ginger extracts (n = 25) group B received placebos (n = 25) twice with lunch and twice with dinner daily for 8 weeks. Results: Compared with placebo, taking dietary supplements containing green tea, capsaicin and ginger resulted in a significant decrease in weight (-1.8 ± 1.5 vs. +0.4 ± 1.2 kg, respectively, p < 0.001) and body mass index (BMI; -0.7 ± 0.5 vs. +0.1 ± 0.5 kg/m2, respectively, p < 0.001). In addition, subjects who received green tea, capsaicin and ginger co-supplements had significantly decreased serum insulin concentrations (-2.6 ± 3.9 vs. -0.6 ± 2.0 µIU/mL, p = 0.02), homeostatic model of assessment for insulin resistance (-0.5 ± 0.8 vs. -0.05 ± 0.6, p = 0.01), and increased quantitative insulin sensitivity check index (+0.01 ± 0.01 vs. +0.001 ± 0.01, p = 0.008) and plasma glutathione (GSH) levels (+73.8 ± 120.6 vs. -28.3 ± 193.4 µmol/L, p = 0.03) compared with the placebo. Conclusions: Our study indicated that taking green tea, capsaicin and ginger co-supplements for 8 weeks among overweight women had beneficial effects on weight, BMI, markers of insulin metabolism and plasma GSH levels.
Genomics Perspectives on Metabolism, Survival Strategies, and Biotechnological Applications of Brettanomyces bruxellensis LAMAP2480
Authors: Godoy Liliana , Silva-Moreno Evelyn , Mardones Wladimir , Guzman Darwin , Cubillos Francisco A. , Ganga Angélica
Published: June 2017

Wine production is an important commercial issue for the liquor industry. The global production was estimated at 275.7 million hectoliters in 2015. The loss of wine production due to Brettanomyces bruxellensis contamination is currently a problem. This yeast causes a “horse sweat” flavor in wine, which is an undesired organoleptic attribute. To date, 6 B. bruxellensis annotated genome sequences are available (LAMAP2480, AWRI1499, AWRI1608, AWRI1613, ST05.12/22, and CBS2499), and whole genome comparisons between strains are limited. In this article, we reassembled and reannotated the genome of B. bruxellensis LAMAP2480, obtaining a 27-Mb assembly with 5.5 kb of N50. In addition, the genome of B. bruxellensis LAMAP2480 was analyzed in the context of spoilage yeast and potential as a biotechnological tool. In addition, we carried out an exploratory transcriptomic analysis of this strain grown in synthetic wine. Several genes related to stress tolerance, micronutrient acquisition, ethanol production, and lignocellulose assimilation were found. In conclusion, the analysis of the genome of B. bruxellensis LAMAP2480 reaffirms the biotechnological potential of this strain. This research represents an interesting platform for the study of the spoilage yeast B. bruxellensis.
Waly Salomão: a poesia da inquietação
Authors: Rebechi Junior Arlindo
Published: June 2017

Apresentação do poeta Waly Salomão, em suas diversas fases de produção, entre os anos 1970 e os anos 2000.
Interfaces da Comunicação e da Educação na escola: a experiência do CAp-UFRJ em diálogo com alunos e professores
Authors: Becker Beatriz
Published: June 2017

A visualidade eletrônica redimensiona as formas de visibilidade da cultura e produz modos distintos de socialização e de significação da experiência. O desenvolvimento e os usos das tecnologias digitais provocam transformações nas maneiras de ler, escrever e entender o mundo e impõem reflexões sobre desafios e potencialidades das interfaces da Comunicação e da Educação na formação escolar. Este trabalho busca identificar como alunos e professores do ensino médio compreendem a relevância da leitura crítica da mídia e de usos de tecnologias digitais em processos de aprendizagem e a pertinência da inserção ou não de uma disciplina sobre Comunicação e Jornalismo na formação escolar, a partir de pesquisa desenvolvida em parceria com o Colégio de Aplicação da Universidade Federal do Rio de Janeiro (CAp-UFRJ).
Educomunicação: Histórias em quadrinhos no ensino de Artes
Authors: Santos Roberto Elísio dos , Santos José Luiz dos
Published: June 2017

Este artigo resulta de pesquisa de mestrado aprovada na Universidade Municipal de São Caetano do Sul (USCS), cujo objetivo foi investigar a utilização das histórias em quadrinhos (HQs) e de fanzines como forma de inovação para a docência da disciplina de Artes no ensino médio. De caráter qualitativo e de nível exploratório, o estudo se desenvolveu na interface dos campos da educação com a comunicação. Este trabalho, portanto, busca identificar referências estéticas comuns a determinadas produções de HQs com relação a períodos específicos das vanguardas modernas da arte. Dentre as conclusões, salientou-se o fato de que é necessário que os espaços escolares ofereçam uma experiência cognitiva que valorize mais as relações sociais, respeitando o direito do jovem à comunicação e à informação. Para que isso fosse possível, propõe-se a realização de oficina de fanzines de quadrinhos.