bluuebunny/crossref_metadata_2025 huggingface dataset:
Pharmacological Effects of Bioactive Compounds From Allium sativum
Authors: Johny Anoop , Mishra Saurav Kumar , J. Georrge John
Published: July 2023

Garlic cultivation has been done in India since time immemorial and ingested in the Mediterranean and China as a flavour-enhancing spice. Various studies have shown immunomodulatory inducing properties in garlic (Allium sativum), with several proofs showing that it tends to have stimulatory and inhibitory effects on lymphocytes. Certain studies have also demonstrated garlic's therapeutic efficacy enhanced upon separating and eliminating parts causative of inflammatory cytokines. This plant belongs to clade: angiosperms, monocots; order: asparagales; family: liliaceae; subfamily: alliodeae; and genus: allium. The therapeutic effects can be attributed to the volatile oils, sugars, starch, mucilage, albumen, and components enhancing activity. Garlic has several attributes, such as its anti-viral, anti-microbial, anti-cancer, and cardiovascular properties and immunomodulatory effects. The mentioned list does not end as it also has several other uses. This chapter tries to encapsulate some of the pharmacological effects and properties of Allium sativum.
Anti-Diabetic Phytochemicals and Their Mode of Action
Authors: Nelli Giribabu , Salleh Naguib , Kumar Gowri Gopa
Published: July 2023

The number of people diagnosed with diabetes mellitus (DM) has risen considerably in recent decades. Diabetes type 1 and 2 are the most frequent types. Type 2 diabetes accounts for 90% of all DM cases globally, making it a 21st-century epidemic. Meanwhile, the side effects and resistance development of routinely used synthetic oral hypoglycemic medications have side effects. It's a need for a safe and less costly substitute. This chapter looks at the anti-diabetic properties of several bioactive compounds derived from plants, such as boldine, bergenin, abietic acid, and myristic acid. This chapter examines the active compounds that can be obtained from plants and their potential use in the treatment of diabetes mellitus, as well as the molecular mechanisms underlying their actions in ameliorating diabetes complications. Consequently, creating novel anti-diabetic oral medications requires a detailed understanding of the mechanisms of action of these phytochemicals.
Natural Products as Alternative Treatments for Bone Disorders
Authors: Nelli Giribabu , Salleh Naguib
Published: July 2023

Bone is an active and dynamic organ that is well-differentiated and originated from mesenchymal cells. Bone goes through constant remodeling during its lifetime. Most bone disorders result in loss of bone mass and microarchitectural deterioration, which leads to more osteoclast-mediated bone resorption than osteoblast-mediated bone formation. Natural products have been used to treat bone disorders since ancient times and have gained favor in recent years. Natural products have grown in popularity worldwide over the last few decades, according to the World Health Organization (WHO), and are now used by 80% of the world's population. This chapter explores the pharmacological actions of some medicinal plants, including Marantodes pumilum, Eurycoma longifolia, and Piper sarmentosum for bone repair. This chapter includes the extensive study of medicinal plants and active compounds with their potential usage in treating bone disorders, as well as the molecular mechanisms underlying their action in reducing osteoclast formation and activity.
“Don't Use Your Own Language in School”
Authors: Sadiq Assadullah
Published: July 2023

The purpose of this chapter is to examine the beliefs of four elementary-aged Afghan refugee children regarding their first-language usage in school, while living in their first asylum country of Pakistan. It shares findings related to the following research questions: What are the beliefs of four elementary-aged Afghan refugee children regarding their first language? What are the teachers' beliefs regarding the use of first language at school? Findings indicated that the children were divided on their perspectives on using their first language at school and the possibility of having a first language class. The female children did not want a Pashto class, while the male focal children welcomed it, with some contradictions from the child in kindergarten. Moreover, most teachers emphasized that Afghan students focus on the school's languages of instructions, English and Urdu, and restricted Pashto to the home. Many teachers believed the first language maintenance should be parents' responsibility and regulated within the home. The author concludes with implications for educators.
A Multiliteracies Approach to Antiracist High School English Language Arts Pedagogy
Authors: Shufflebarger Amanda Marie
Published: July 2023

Drawing upon the construct of multiliteracies, this chapter will explore how teachers can make discursive decisions at the classroom level to affirm students' linguistic, cultural, and racial backgrounds in the secondary English language arts (ELA) classroom. Following a multiliteracies theory of design, the chapter will consider how teachers can design ELA classroom materials that deliberately affirm and honor the voices of all students, even when they are not supported by anti-CRT public discourse. The author uses a case study to explore how the author intentionally created student-affirming materials and facilitated meaningful discussion while also navigating institutional challenges such as high-stakes testing, learning during COVID-19, administrative upheaval, and anti-CRT state politics as an urban high school ELA teacher.
Empowering Students to Cultivate Better Writers
Authors: DiCicco Michael , Sherry Tammie , Butts Jackie
Published: July 2023

Students often experience academic writing in school as difficult, irrelevant, and hard to focus on. Student voice has been shown to have a positive effect in the education of young adolescents including better grades, attendance, and increased engagement in their learning. When students are motivated and feel positive about their writing, their writing performance is improved. This chapter presents the process, product, and reflection of a student-led inquiry project aimed at empowering students and improving their writing by three literacy educators. Sixth-grade students generated issues important to them, researched topics, decided on solutions, and carried out those solutions. Researchers recorded student conversations, collected writing, and artifacts from the project. They reflect on the process including teacher bias, honoring student choice, and the importance of prewriting. Suggestions for practice and implications are provided.
Dialogic Interactions in Genre-Based Writing and Learning
Authors: Traga Philippakos Zoi A. , Voggt Ashley
Published: July 2023

Oral interactions can take place across grades and across disciplines, making dialogic practice a universal approach to thinking and learning. In this chapter, the authors address the application of dialogic interactions within the developing strategic learners writing approach that connects thinking, listening, speaking, reading, and writing supporting learners' goal setting and writing performance across genres. The authors explain the genre-based instructional principles and pedagogical approaches on writing instruction and the use of dialogic discourse when writing to argue, to inform, and to narrate. Finally, they offer recommendations for effective dialogic interactions across disciplines.
Optimization of Laser Beam Machining Process Parameters of HSLA Steel Using MOORA
Authors: Praveen D. Vijay , Umamaheswarrao P. , Suresh Avula , Musharaf Shaik , Praveen S. , Abdulla Shaik P. , Kumar T. Sahit
Published: July 2023

The current research paper is focused on investigating the influence of Laser beam machining process parameters on surface roughness and kerf width of HSLA steel. Taguchi’s L18 orthogonal array is adopted to conduct the machining studies. MOORA method is used to evaluate the suitable combination of the LBM process parameters. The combined effect of machining performance measures is analysed using analysis of variance to identify the significance of the result. Consequently, the influence of the parameters on machining responses were explored. The surface morphology of the machined surface of the optimal set of parameters has been studied.
Mechanical Behaviour of Geopolymer Concrete Using Steel Fibers
Authors: Dhanalakshmi Ayyanar , Shahul Hameed Masthan Ali , Kaliraj Priyanka , Velci Shridevi Paulraj , Rajendrakani Kumar
Published: July 2023

This investigation inspects the concurrent influence of steel fibers with different materials such as Fly Ash(FA), Silica Fume(SF) and aggregates on the mechanical behaviour of geopolymer concrete (GPC) mixes. A range of 8 to 16 molar NaOH molarities variation was observed in the experimental work. Sodium hydroxide molar (NaOH) and sodium silicate solution (NaOH) were utilised as alkaline activators in proportions of 1, 1.5, and 2 (Na2SiO3/NaOH). Steel crimped fibers having aspect ratio of 60 were added in the geopolymer concrete. Geopolymer concrete properties considering type of fly ash, the quantity of fly ash, silica fume, the content of fine aggregate and coarse aggregate, effect of sodium hydroxide concentration, content of sodium silicate solution and inclusion of 0.2% of steel fibers in the geopolymer concrete are analyzed.
Ductile Behaviour of Fiber Reinforced Self Compacting Concrete Beam with Alternative Detailing
Authors: Kaliraj Priyanka , Shahul Hameed Masthan Ali , Dhanalakshmi Ayyanar , Rajendrakani Kumar , Velci Shridevi Paulraj
Published: July 2023

Self-compacting concrete is one of the major advancements in construction. The purpose of this investigation is to evaluate how self-compacting concrete with steel fibres and the appropriate superplasticizer for M30 grade is presented. Effects of combining quartz flour 0 %,5 %,10 %, 15 %, 20 % and steel fibre 0 %,0.25 %,0.50 %,0.75 %, 1 % in varying amounts adding with cement. An experimental study was conducted on the fresh and hardened states of concrete. The optimal combination of quartz flour and steel fibre reinforced concrete was discovered while comparing the mixes to conventional concrete. Quartz flour with ultra-fine particles can fill holes and improve permeability resistance as well as bonding. As a result, utilizing this combination of quartz flour in self-compacting beams, studies explored the strength and ductile properties of normal and ductile details in beams, as well as comparing them to standard self-compacting concrete. Because self-compacting concrete is brittle by nature, adding fibres increases its tensile strength and ductility. Mineral admixtures improve the flow qualities.
Study and Investigation of Microbial Influenced Corrosion Effect for Performance Analysis of Vortex Tube on Stainless Steel with and without Coating
Authors: Suresh Ganta , Vinod Kumar T. , Ananda Kumar Eriki
Published: July 2023

Alloy material testing for stable the properties of Vortex tube and corrosion resistance, this research for specially for fabrication of Vortex tube and also in future may supplier will ask the properties and testing evidence we are going to provide week wise testing schedule. Microbial Influenced Corrosion (MIC) is a type of corrosion that happened on a metal's surface under the seawater. MIC occurs due to the colonization of microorganism on the surface, these microorganisms may be fungus, bacteria or algae. In this paper the E. Coli bacteria are used to investigate the MIC on metal sample of vortex chamber. A metal sample of vortex tube which is stainless steel is coated with different coating such as alocit, rubber, epoxy, and graphene. The samples for vortex tube with different coating are tested to find out the best one which can resist MIC better than the others. There are different tests carried out; wet and dry test, atmospheric test. To find the corrosion progress the weight loss and corrosion rate is found in the sample material to apply vortex tube. The hardness of the coating is done to find the best one. The optical microscope is used to understand the corrosion progress in the metal surfaces and for the hardness test. The result analyzed shows that graphene is the best coating because of its excellent properties in resisting and preventing MIC corrosion of vortex tube is a non-conventional cooling device, having no moving parts which will produce cold air and hot air from the source of compressed air without effecting the environment when a high-pressure air is tangentially injected into the vortex chamber, a strong vortex flow will be created which will be split into two air streams. Beyond that, the improvement in energy separation is minor, and Vortex Tube performance begins to deteriorate as shock waves form outside the nozzle. Without any moving parts or chemical reactions, a vortex tube (VT) can generate hot and cold streams from a single pressurised room temperature fluid.
Effects of SARS-CoV-2 infection on pregnancy outcome: An overview
Authors: Amin Yahia A.
Published: July 2023

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may have harmful effects on expectant moms, labor, and newborns born to infected mothers. There is a risk of the initiation of pregnancy with infection. Even if the gametes are non-infected, pregnancies could be exposed later for infection by coronavirus. Investigations of COVID-19 during pregnancy highlighted the non-transmission or surprising transmission of SARS-CoV-2 to the offspring. However, other studies have exhibited the potential mother-to-fetus transmission. In this way, unanswered concerns about SARS-CoV-2 fetal transmission and the particular interface(s) controlling its pathogenesis throughout pregnancy persist. This review focuses on the potential effects of SARS-CoV-2 on vertical transmission, as well as the influence of the virus on pregnancy and placenta.
Plantain-based diet modulates atrazine-induced testicular toxicities in rats
Authors: Rotimi Damilare Emmanuel , Adeyemi Oluyomi Stephen
Published: July 2023

Objective:

To assess the potential of plantain-based diet in modulating testicular toxicities in rats exposed to atrazine.

Methods:

The plantain-based diet at 50%, 25% and 12.5% were prepared from the basal diet by substituting the corn starch with plantain fruit pulp flour at different percentages. Wistar rats were fed plantain-based diet in varying concentrations ranging from 12.5% to 50% of the basal diet for 21 days before or after atrazine treatment in a two-phase experiment: preventive and therapeutic phases. The therapeutic model (n=35) had seven groups with 5 rats each, including the control, atrazine, atrazine recovery, atrazine plus plantain-based diet 50%, 25%, 12.5%, and atrazine plus quercetin groups. The preventive model (n=30) had six groups of 5 rats, consisting of the control, atrazine, 50%, 25%, 12.5% plantain-based diet plus atrazine, and quercetin plus atrazine groups. Gonadal hormones (testosterone, luteinizing hormone and follicle-stimulating hormone), sperm parameters (sperm motility, viability, morphology and concentration), and testicular function indices (protein, cholesterol, glycogen, acid phosphatase, alkaline phosphatase and lactate dehydrogenase) were measured.

Results:

The gonadal hormones, sperm characteristics, and testicular function indices of the rat testis decreased significantly in the atrazine group alongside degeneration of the histoarchitecture. However, plantain-based diet restored the gonadal hormone concentrations, semen parameters, and testicular function indices in both the preventive and therapeutic models.

Conclusions:

Treatment with plantain-based diet protects against rat testicular toxicity caused by atrazine via the modulation of gonadal hormones, sperm quality, testicular function index as well as histoarchitecture of rat testes.
Anticancer Effects of Gingerol, Shogaol and Curcumin in Cervical Cancer: A Systematic Review Protocol
Authors: Abdull Rahim Unwaniah , Che Roos Nur Aishah , Mustapa Marami , Nurdin Armania , Taridi Nursiati Mohamad , Mohd Yusof Yasmin Anum
Published: July 2023

Background:

Cervical cancer has accounted for the top-four cancer incidences occurring among females worldwide. Despite the availability of anticancer drugs as one of its treatment modalities, they are not without adverse effects. It has come to researchers’ attention that natural bioactive compounds have anticancer properties, as reported in many pre-clinical studies.

Materials and Methods:

This systematic review protocol conforms to the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols-P guideline and Population, Intervention, Comparison Outcome and Study framework. Electronic databases, including PubMed, Scopus and ScienceDirect, will be searched from inception until May 2022 for articles published in English. Only studies that investigate the effects of curcumin, gingerol, shogaol and/or their combination in human cervical cancer cell lines and/or rodent animal models implanted with cervical cancer xenografts will be included. A customised risk-of-bias tool (RoB) and the Systematic Review Centre for Laboratory Animal Experimentation’s RoB will be used to assess the quality of in vitro and in vivo studies, respectively. Where appropriate, a meta-analysis will be performed using RevMan version 5.4.

Conclusions:

Findings obtained from this review may be used as valuable evidence to guide and direct future studies pertaining chemopreventive effects of bioactive compounds in cervical cancer. This protocol is registered on PROSPERO (CRD42022334940).
High-grade endometrial stromal sarcoma displaying immunohistochemical expression of BCOR—A report of two cases of a novel tumor entity
Authors: Wagh Varsha , Menon Santosh , Maheshwari Amita , Gupta Sudeep , Deodhar Kedar K. , Rekhi Bharat
Published: July 2023

Several defining molecular alterations have recently been identified underlying high-grade endometrial stromal sarcomas, such as YWHAE: NUTM2A/B fusions, ZC3H7B: BCOR fusions, and BCOR internal tandem duplication (ITD). BCOR is a useful immunohistochemical marker for identifying these tumors. A 37-year-old lady was presented with a 10-cm-sized tumor in the pouch of Douglas, involving the vaginal vault, bilateral adnexa, and peritoneum. A 53-year-old lady with a prior hysterectomy was presented with a 12-cm-sized tumor in the vault with abdominal deposits. Histopathological examination of both tumors revealed atypical cells comprising oval to spindle-shaped nuclei, a variable amount of myxoid stroma, and mitotic figures exceeding 10/10 high power fields. Immunohistochemically, the former tumor was diffusely positive for CD10, and the second tumor displayed patchy staining. Both tumors were positive for BCOR. Estrogen receptor (ER) showed variable staining in both tumors. By fluorescence in-situ hybridization (FISH), both tumors lacked YWHAE gene rearrangement. Both tumors had an aggressive clinical course, including extensive involvement This constitutes the first report of BCOR-positive high-grade sarcomas involving the female genital tract from our subcontinent. BCOR is a useful immunostain for identifying these relatively aggressive tumors. The differential diagnoses and the prognosis of these ultra-rare tumors are discussed herewith.
Post-mortem detection of a calcifying fibrous pseudotumor at a rare site—A case report
Authors: Mylapalli Jhansi L. , Jangir Hemlata , Sharma Meenakshi , Prabhakar Vidhu , Sandhu Piyush R. , Subramanian Arulselvi , Barwad Adarsh , Lalwani Sanjeev
Published: July 2023

We report the case of a 48 year old man brought-in-dead to the trauma unit following an alleged accidental fall from a multi-storied building. Autopsy findings were consistent with traumatic injuries to the head, chest and spine. Incidentally, a bit of the diaphragm with a pearly white lobulated mass over the pleural surface was observed. Histopathological examination detected a calcifying fibrous pseudotumour (CFPT), confirmed by positive immunostaining for cluster of differentiation protein-34 (CD34) and vimentin (focally). CFPTs are slow-growing pseudotumours that are clinically benign with extremely low rate of recurrence and this might just be the first reported case of CFPT on the diaphragm. This shall further aid clinicians to diagnose these rare yet significant soft tissue tumors in uncommon sites.
Assessment of endometrial carcinoma on biopsy as a predictor of final surgical pathology: Are we doing it right? A completed audit cycle and recommendations
Authors: Jassar Aneeta , Hemali Nour , Bhatnagar Anjali
Published: July 2023

Background:

Typing and grading of endometrial carcinomas (ECs) on small biopsy specimens is crucial to determine the need for full surgical staging. Histological subtype and grade are key factors available for risk stratification before surgery. However, this can be diagnostically challenging on small biopsy specimens, especially when morphologic features are subtle or overlapping.

Aims:

The aims of this audit were to assess concordance of endometrial carcinomas on biopsy specimens with hysterectomy specimens and to determine if the immunohistochemistry (IHC) panel being used in our practice was adequately subtyping ECs.

Settings and Design:

The audit was approved by the Clinical Effectiveness Team of the Royal College of Pathologists (UK) as meeting all the criteria and standards set out by the College.

Materials and Methods:

Biopsies from 67 cases of EC were compared for histological subtype and grade of endometrioid carcinoma with resection specimens. A re-audit was carried out on 59 cases after implementation of changes recommended by the initial audit.

Results:

Two of 35 (6%) tumours defined as G1 on biopsy were upgraded (to G2) on final pathology, as was one of 7 (14%) G2 tumours (to G3). One of these cases had solid areas just amounting to more than 6% on resection. In the second case, a comment was made that assessment had been difficult as the specimen was suboptimally fixed, but nuclei appeared atypical. Of seven G2 biopsies, one case was upgraded to grade 3 on final pathology based on proportion of solid areas. Our data show lower rates of discordance as compared to previous studies and on re-audit, the concordance between endometrioid and nonendometrioid serous carcinoma improved with the addition of immunohistochemistry (IHC) for Phosphatase and tensin homolog (PTEN) to biopsies.

Conclusions:

PTEN IHC can complement other stains and aid in the distinction of grade 3 endometrioid carcinoma from serous carcinoma on endometrial biopsies.
Endocardial fibroelastosis causing sudden death in an infant: Autopsy case report of an unusual lesion
Authors: Mohan Bhavya P. , Rajendraprasad V. K. , Parthasarathy K. S. , Zacharia Togy Thomas
Published: July 2023

Endocardial fibroelastosis is characterized by proliferation of both elastic and collagenous fibers within the endocardium, causing diffuse or localized thickening. A four-and-a-half-month-old baby was admitted to a local hospital, with a history of seizures for one day. Baby developed features of heart failure and died within one week after admission. At the post-mortem examination, heart was found to be enlarged with dilated ventricles. The endocardium of left ventricle was markedly thickened with a whitish appearance. Histopathology showed a thick layer of collagenous fibrous tissue in the endocardium, which was confirmed by Masson trichrome stain. The cause of death was offered as dilated cardiomyopathy due to endocardial fibroelastosis. The underlying mechanisms of myocardial fibrosis remain unclear. It is hypothesized that genetic, infectious, inflammatory, and nutritional processes are involved in this condition. This case highlights the importance of gross specimen examination and special staining methods to support histopathology after postmortem examination, for ascertaining the cause of death.
Functional outcome of limited contact dynamic compression plating and interlocking nailing for fracture shaft of humerus in adults
Authors: D’Almeida Vivian Roshan , Kamath Ashwin , Joseph Akhil Xavier , Lobo Alfred Manoj , Pinto Tilak Rommel
Published: July 2023

Background:

Fractures of shaft of humerus are common, accounting 3% of all fractures. They have historically been managed conservatively with hanging casts or a functional brace. However, a lack of fracture reduction with these conservative measures resulted in malunion. Two surgical techniques under study include intramedullary nailing and limited contact dynamic compression plating. This study aims to analyze the functional outcome between the two surgical techniques.

Materials and Methods:

In this prospective randomized study, 38 patients were treated surgically for shaft of humerus fracture from August 2016 to August 2018 at a tertiary care center. Twenty patients underwent limited contact dynamic compression plate (LCDCP) plating and 18 underwent intramedullary nailing. All were assessed for radiological union, complications, and functional outcome at 6 weeks, 12 weeks, and 1 year using disabilities of arm, shoulder, and hand (DASH) questionnaire.

Results:

Thirty-eight patients completed the study of which 18 cases (47.5%) with fractures that were treated with interlocking nail and 20 cases that were treated with LCDCP plating. The mean duration to complete radiological healing was 15.06 weeks. The healing rate was relatively faster in the interlocking group as compared to the LCDCP group (P = 0.144). Complications such as shoulder impingement 8 (44.4%), shoulder pain 3 (16.7%), nonunion 1 (5.6%), and shoulder stiffness 1 (5.6%) were found to be more common in interlocking group as compared to LCDCP group, respectively. Whereas, complications such as superficial infection - 1(5%) and radial nerve deficits - 2(10%) were less common in the interlocking group compared to LCDCP group, respectively. The mean follow-up was 11.556 weeks, and the overall DASH score analysis showed better results in LCDCP group.

Conclusion:

In our study, LCDCP plating showed lower incidence of complications, particularly periarticular complications around the shoulder joint such as shoulder pain, stiffness, and impingement but carried a higher risk of radial nerve injury. Fracture union rates were found to be almost similar between both groups. DASH score analysis showed better functional outcome among the LCDCP plating group. The overall outcome of LCDCP plating over interlocking nailing was found to be better.
Correlation of serum ferritin with severity of liver disease
Authors: Blah Garyll Ryan Tariang , Tonk R. S.
Published: July 2023

Background and Aim:

Serum ferritin is a marker of hepatic inflammation and has been studied to predict mortality in decompensated cirrhotics. No study has been done to evaluate ferritin as an independent marker of liver disease severity. We investigated whether serum ferritin levels can be correlated with Child–Pugh and Model for End-stage Liver Disease (MELD) scores.

Materials and Methods:

Seventy-five patients fulfilling the criteria were included and a cross-sectional observational study was done.

Results:

Seventy-five patients (68 males and 7 females) were evaluated. Serum ferritin levels were found to be significantly elevated in patients having higher Child–Pugh and MELD scores and showed a significant correlation with Child–Pugh score (P = 0.001) and MELD score (P = 0.027). On univariate analysis, serum ferritin, bilirubin, international normalized ratio, ascites, and sodium were found to be significantly associated with severity of liver disease. On multivariate analysis, however, serum ferritin was not found to have a significant association with severity of liver disease. AUROC was also determined which showed that serum ferritin had relatively poor discriminative ability.

Conclusion:

Elevation of serum ferritin is prevalent in chronic liver disease (CLD). In patients of CLD, severity is associated with a higher serum ferritin level. In future, a study may be designed, to obtain a prognostic model in incorporating serum ferritin into MELD similar to MELD-Na scoring system.
Human papilloma virus-related oral and oropharyngeal squamous cell carcinoma: An assessment of histomorphological features
Authors: Lenka Anasuya , Ghosh Urvashi , Mohapatra Debahuti , Tripathy Rajashree
Published: July 2023

Background:

Human papillomavirus (HPV) has emerged as an important cause of oral and oropharyngeal squamous cell carcinomas (OSCC and OPSCC). Cancers with HPV as a causative agent are seen to exhibit certain specific histomorphological features.

Aim:

This study aims to describe the histomorphology of oral and oropharyngeal cancers and discuss their association with HPV.

Material and Methods:

Hospital-based prospective study done over 31 months (December 2018–April 2021), including a total of 90 cases of OSCC and OPSCC. They were subjected to detailed histopathological evaluation, DNA polymerase chain reaction testing for testing of HPV association, followed by the analysis of data by statistical methods.

Results:

Out of a total of 90, 73 cases were OSCC and 17, OPSCC. A total of 15 cases were HPV positive. HPV status was found to be significantly associated with purely nonkeratinizing tumors and hybrid/mixed squamous cell carcinomas, pushing the pattern of invasion, absence of perineural invasion, presence of tumor infiltrating lymphocytes, moderate-to-dense host lymphocyte response, loose stromal response, absence of tumor budding, and high mitotic rate (>20/10 hpf).

Conclusion:

HPV-positive OSCC and OPSCC have distinct histomorphological features and careful analysis of the same can assist in identifying these types of cancers better and thus help in prognostication and treatment.
hegemonía populista: discurso, ideología y políticas en el gobierno de Cristina Fernández de Kirchner
Authors: Varesi Gastón Ángel
Published: July 2023

El artículo analiza la construcción de una hegemonía populista durante el período kirchnerista en Argentina. Desde una perspectiva gramsciana que recupera el enfoque del Príncipe moderno, articulamos tres acepciones del concepto de populismo para el estudio del discurso, la ideología y las políticas; así, buscamos reponer claves de lecturas del Príncipe como líder y representación simbólica de una voluntad colectiva y el Príncipe moderno como fuerza política y sujeto colectivo dirigido a aportar a la organización de dicha voluntad. Asimismo, el populismo como discurso político particular, como lógica de articulación de demandas populares y como estrategia de pacto social conforma las tres vías de análisis para preguntarnos por la construcción de hegemonía. Se sintetizan aspectos generales del ciclo de gobiernos kirchneristas desde 2003, para centrarse en el último mandato de Cristina Fernández (2011-2015). Reconstruimos el contexto de cada año, trabajando, por un lado, sobre un corpus de 60 discursos que incluyen las aperturas de sesiones del Congreso, fechas patrias significativas, intervención en foros internacionales, alocuciones hacia la militancia y presentación de las principales políticas del período y, por otro, abordando el análisis de dichas políticas a través de documentos oficiales, leyes, decretos e indicadores socio-económicos.
Bienes comunes cognitivos y gestión del conocimiento en proyectos de ciencia abierta
Authors: Roca-Petitjean Santiago José
Published: July 2023

Este artículo aborda su objeto de interés a la luz de tres enfoques. En primera instancia, se parte de la concepción del conocimiento como bien común, o recurso de propiedad colectiva manejado participativamente por una comunidad. En segundo lugar, se pretende mostrar que el conocimiento puede manejarse colaborativamente a través de técnicas de gestión del conocimiento que favorezcan la diseminación del saber y el trabajo en red. A la postre, ambos conceptos encuentran relevancia en el marco de la ciencia abierta, como concepto que abarca diferentes prácticas de libre acceso al conocimiento paulatinamente adoptadas por la academia. Por lo tanto, el objetivo de este trabajo es exponer que la gestión del conocimiento puede apoyar procesos de creación y manejo de bienes cognitivos en el marco de la ciencia abierta. Para ello, se exploran dos marcos conceptuales principales: conocimiento como bien común y gestión de conocimiento. Luego se presenta un caso de reflexión en ciencia abierta: la producción de bienes cognitivos de conocimiento libre en un Centro de Desarrollo e Investigación. Entre las conclusiones, se explica que la gestión del conocimiento como bien común constituye una disciplina pertinente para canalizar la ejecución de proyectos de ciencia abierta.
democracia ambiental. Preservar nuestra parte de la naturaleza
Authors: Balbontín-Gallo Cristóbal
Published: July 2023

La aparición de este ensayo de Éric Pommier, académico de la Pontificia Universidad Católica de Chile y miembro asociado de los Archivos Husserl de París, constituye una excelente ocasión para reflexionar sobre el estado de la filosofía ambiental. Su publicación, consistente en su traducción al español de la obra aparecida originalmente en francés (La démocratie environnementale. Préserver notre part de nature), viene a sumarse en Chile a la reciente reflexión filosófica de Sara Larraín (2021) sobre cómo actuar en defensa de la perseveración de la vida.
Steel Bars, Forgings, Mechanical Tubing and Forging Stock 0.88Cr - 1.8Ni - 0.42Mo - 0.08V (0.28 - 0.33C) (4330 Mod) Consumable Electrode Remelted
Authors:   AMS E Carbon and Low Alloy Steels Committee
Published: July 2023

This specification covers a premium aircraft-quality, low-alloy steel in the form of bars, forgings, mechanical tubing, and forging stock.
Early Neolithic imagery in flux
Authors: Dietrich Oliver , Wagner Julia
Published: July 2023

Stone is often regarded as the ideal medium for the long-term preservation of knowledge, as it is resistant to change. Early to middle Pre-Pottery Neolithic Göbekli Tepe in southeastern Turkey has repeatedly been treated as a prime example for such external memorial storage in durable stone. The present paper challenges this view. A close examination of pillars and their reliefs in Building F reveals the fluid character of imagery with repeated and frequent phases of erasure and re-making. It is argued that it is not the durability of stone that made it suitable for the preservation of ‘cultural memory’, but the possibility to re-shape the image carriers continuously over a long period of time, which resulted in processes of transmission, learning and memorization.
Critical notes on some recent Neo-Kaleckian contributions on capacity utilization
Authors: Gahn Santiago José
Published: July 2023

Within the non-mainstream growth literature, the Neo-Kaleckian model is the only one that presents an endogenous capacity utilization in the long run. After systematizing the debate around recent contributions, presenting the baseline and extensions of the Neo-Kaleckian model and providing some notes on the normal rate of capacity utilization, I critically assess three recent alternatives that try to justify endogenous utilization in Neo-Kaleckian models. All these contributions present different theoretical and empirical shortcomings that should be addressed in order to substantiate their claims.
The effect of public social expenditure on imports
Authors: Garcimartín Carlos , Marmolejo Arnoldo L. , Eggers Carlos
Published: July 2023

This paper studies the effect of social expenditure on imports. In doing so, it uses cross-country panels of the world economy to estimate an augmented balance-of-payments-constrained growth model that takes into account social spending. The results show that social expenditure reduces imports and offsets the negative effect it could have on the balance of trade through its effect on exports. We also find that for OECD countries, education spending is relevant to imports but not to exports, for which the most relevant component is spending on social protection (old-age and unemployment benefits). This result is particularly relevant for development policy in countries with low social expenditure.
The use of music in therapy through the ages
Authors: Gandolfo Gabriel , Hugues Marina
Published: July 2023

If we define music therapy as the use of music to promote, maintain or restore health on a physical, mental, emotional or even spiritual level, we are highlighting the multiplicity of music's effects on the organism and the variety of its uses over the centuries and in different civilizations. Let's not forget that many physicians, from Hippocrates, considered the "father" of medicine, and Empedocles to Rabelais, were also musicians. Let's take a look at the history of the relationship between music and medicine, and how it has evolved from its original curative purpose to its modern preventive use to ensure a form of well-being.

Si on définit la musicothérapie comme l’usage de la musique afin de promouvoir, maintenir, restaurer la santé sur le plan physique, mental, émotionnel voire spirituel, on souligne ainsi la multiplicité des effets de la musique sur l’organisme et la variété de son utilisation au cours des siècles et dans les différentes civilisations. N’oublions pas que bon nombre de médecins, depuis Hippocrate, considéré comme le « père » de la médecine, et Empédocle jusqu’à Rabelais, étaient aussi des musiciens. Dressons donc un panorama historique des rapports qui ont existé entre musique et médecine et leur évolution d’un objectif originellement curatif à un usage moderne également préventif afin d’assurer une forme de bien-être.
On Convergence of Binary Trust-Region Steepest Descent
Authors: Manns Paul , Hahn Mirko , Kirches Christian , Leyffer Sven , Sager Sebastian
Published: July 2023

Binary trust-region steepest descent (BTR) and combinatorial integral
approximation (CIA) are two recently investigated approaches for the solution
of optimization problems with distributed binary-/discrete-valued variables
(control functions). We show improved convergence results for BTR by imposing a
compactness assumption that is similar to the convergence theory of CIA. As a
corollary we conclude that BTR also constitutes a descent algorithm on the
continuous relaxation and its iterates converge weakly-$^*$ to stationary
points of the latter. We provide computational results that validate our
findings. In addition, we observe a regularizing effect of BTR, which we
explore by means of a hybridization of CIA and BTR.
Uso de Blackboard y aprendizaje efectivo en una institución de educación superior
Authors: Meza Castillo Erick , Espinoza Polo Francisco Alejandro
Published: July 2023

Este estudio cuantitativo buscó determinar la relación entre el uso de la plataforma virtual Blackboard y el aprendizaje efectivo en estudiantes de en una Institución de Educación Superior de Chimbote en el año 2022. Se utilizó un cuestionario propio para analizar una muestra de 155 estudiantes de un total de 520. El instrumento fue validado a través de un juicio de expertos y la confiabilidad se determinó mediante el alfa de Cronbach (KMOPlataf=0.775 KMOAprend=0.924 αPlataf=0.921 αAprend=0.958.). Los resultados destacaron que el uso de la plataforma virtual Blackboard tiene un impacto directo y significativo en el aprendizaje efectivo (r2=0.669). Por lo tanto, se recomienda su uso más amplio para mejorar la calidad del aprendizaje.
Liderazgo directivo en el desempeño docente y administrativo de un Instituto Superior.
Authors: Cruz Aranda Yrma Graciela , Cerna Quispe Gladys Virginia
Published: July 2023

El éxito de las instituciones depende directamente del tipo de liderazgo que adopte la máxima autoridad que la dirige, que para el caso de los centros educativos es el director de turno quien, en base a su dedicación, conocimientos, inteligencia emocional, buena toma de decisiones entre otros, va a influir positiva o negativamente en el desempeño del personal, de manera indirecta en la formación académica de los estudiantes y el crecimiento institucional. En este contexto, el presente estudio tuvo como objetivo determinar la influencia del liderazgo directivo en el desempeño docente y administrativo de un Instituto de Educación Superior Tecnológico de Chepén. La investigación se basó en un enfoque cuantitativo, diseño no experimental de cortetransversal, correlacional causal comparativa, de tipo explicativa. De la población de estudio se tomó una muestra de 91 estudiantes matriculados en el último año, seleccionados de manera aleatoria utilizando el muestreo probabilístico. La técnica utilizada fue la encuesta, aplicando un cuestionario sobre Liderazgo directivo y desempeño docente y administrativo como instrumento. El contenido del cuestionario se validó mediante juicio de expertos en la materia, la validez de constructo de liderazgo directivo, desempeño docente y administrativo muestra un KMO = 0,898; Sig.<1%; y la fiabilidad interna presenta un (α) Cronbach=0,947. Los resultados evidencian que existen relaciones moderadas directas, significativas al 1%, determinándose lainfluencia moderada positiva y significativa del liderazgo directivo y sus dimensiones con el desempeño docente y administrativo.
The Mathematical Outcome of The IVF, Including Early Cleavage
Authors: OR Simge , ÖÇAL Pelin , DAYIOGLU Nurten , İREZ Tülay
Published: July 2023

Bu araştırmada IVF (In Vitro Fertilizasyon) başarısı için
bağımsız faktörlerin incelenmesi amaçlanmıştır. Anti-Mullerian Hormon (AMH), Folikül Uyarıcı Hormon
(FSH) gibi hormonlar, embriyoya dönüşen oositin büyüme aşamaları (total döllenmiş oosit, erken bölünme vb.),
tıbbi ayarlamalar dahil edildi.
Bağımlı faktörümüz olan döllenme başarısı ve gebelik iki
gruba ayrıldı; diğer bir deyişle gebelik başarısı için ikili lojistik regresyon incelendi.
Çalışmamızın istatistiksel anlamlılığı için Model Katsayılarının Omnibus Testleri (p-değeri=0,008) ve Hosmer ve
Lemeshow testleri (p-değeri=0,462) yapıldı.Modelimiz
istatistiksel anlamlılık yoluyla başarılı oldu.P değeri sıfıra
yakın Ki-Kare testi ile Tüp Bebek (Tüp Bebek) için 35 yaş
altı ve üstü kadınların yaş gruplarına göre farklı olduğu
kanıtlandı.
Çalışmamız sonuçlarına göre , erken segmentasyon gebelik şansını artırmakta; buna karşılık kadının yaşı ve bazal
serum FSH düzeyi gebelik olasılığını azaltmaktadır.
Fundamentals of building Construction Materials Using the WASPAS Method
Authors: Jaya dev
Published: July 2023

construction material is for construction material used. Clay, rocks, sand, wood, and branches naturally leave buildings with many materials that occur used for construction. Naturally occurring substances, many are man-made products are in use, some more and some less artificial. As jio products, building materials called from a variety of settings are quarried and mined. To discover new resources because the pressure is increasing the world's growing population and pressure to hold increases. Adobe bricks stone and clay are from ancient times and were the major building materials of the world, and concrete is long and venerable history. These items are still in demand, and any other quarry for their kinds of extractive industry same environment as same creates problems. Research significance: this is a list of building materials. Buildings and structures many in the construction industry create kinds of building materials that are used. Construction is used for projects to specify materials and methods, architects and construction in this category by project manager’s materials and products are used. Cold such as rolled steel framing some building materials, blockwork, and traditionally wood modern rather than slow methods are considered as methods of construction. Many different building materials applications include; therefore, a product for your needs whether it is most suitable consult the manufacturer to verify always well. WASPAS method weighted sum model (WSM) and weighted product model wpm use benefits. Integrating wsm and wpm, ranking of waspas alternatives increases accuracy. That at this stage, wasps is an optimum calculates the additive parameter, which will be given in detail later. The waspas method of analysis is excellent and the best solution. Short distance and negative-best are more than the solution the long-range solution determines, but a comparison of these distances is not considered significant.Alternative: building environmental design and performance, environmental product declarations, harmonized technical specifications, efficient manufacturing of construction materials, governmental support to enterprises. Evaluation preference taken as USA, UK, Australia, Japan. from the result, it is seen that efficient manufacturing of construction materials got the first rank whereas environmental product declarations is having the lowest rank..Conclusion: since environmental production announcements have a very low position, the efficient production of construction materials is obtained by the first ranking.
Effects of Characteristics of Sisal Fiber using the SPSS Method
Authors: Jaya dev
Published: July 2023

The distinguishing qualities or traits of anything are its characteristics. They can be viewed as traits that set one person or thing apart from another. For instance, the chameleon's ability to blend in is one of its traits. Soft, straight, and golden in color, sisal fibers are. Sisal can have long or short fibers because it is extremely coarse and rigid. Because of its strength, toughness, stretch ability, compatibility with some colors, and resilience to degradation in saline water, sisal is prized for use as cordage. Sisal can be fashioned into carpets, mats, and a variety of handicrafts in addition to its traditional applications as rope, ropes, string, and yarn. Sisal fiber is a tough, robust material with low flexibility that is obtained from freshly cut leaves of the plant. It is crucial in the production of materials like carpeting, coarse purses, maritime rope (where strong resistance to saltwater is required), and cordage. Research significance: In recent years, materials engineers and material scientists have paid close attention to sisal-fiber reinforced composites as a type of environmental composites. Effects of fiber surface treatment on fiber compressive properties and fiber-matrix are discussed in this article. Tensile as well as single-strand strand pull tests were used, respectively, to assess the interfacial characteristics. For assessing the implies that the average shear resistance of composite laminates, a short beam shearing test was also carried out. High density polyethylene (HDPE), vinyl ester, and epoxy were selected as the matrix materials. Two different fiber surface-treatment techniques, chemical bonding and oxidation, were used to boost interfacial strength. According to the results, different fiber surface-treatment techniques had varying effects on the tensile strength of sisal fiber, as well as the strength and bonding characteristics of the fiber-matrix interface. As a result, this work can provide important knowledge on jute fiber-polymer matrix compound interface design. Method: Ratio studies are statistical analyses of data from appraisals and property valuations. Nearly all states utilize them to produce quantitative measure of the proportion of current market price about which individually estimated taxable property is appraised as well as to offer assessment performance indicators. Evaluation parameters: Fiber diameter (mm), Water content (%), Tensile strength(MPa), Tensile modulus(GPa) and Elongation at break (%) Result: The Cronbach's Alpha Reliability result. The overall Cronbach's Alpha value for the model is .658 which indicates 66% reliability. From the literature review, the above 50% Cronbach's Alpha value model can be considered for analysis. Conclusion: Characteristics of sisal fiber the Cronbach's Alpha Reliability result. The overall Cronbach's Alpha value for the model is .658 which indicates 66% reliability. From the literature review, the above 50% Cronbach's Alpha value model can be considered for analysis.
Presentación del Dossier: Feminismos y posthumanismo
Authors: Campagnoli Mabel Alicia , Di Pego Anabella
Published: July 2023

Presentación del Dossier: Feminismos y posthumanismo