bluuebunny/crossref_metadata_2025 huggingface dataset:
Skuteczność (w) edukacji a kategoria harmonii wewnętrznej nauczyciela
Authors: Pękala Joanna Ludwika
Published: July 2024

Współczesne skupienie na skuteczności edukacji jest błędnie zawężane do kategorii wydajności mierzonej metodami ilościowymi. Takie traktowanie nauczycieli i ich działań pedagogicznych może być dla edukatorów źródłem ambiwalentnych odczuć w stosunku do własnego zawodu. Autonomia i poczucie własnej skuteczności to podstawa wewnętrznej harmonii nauczyciela rozumianej jako swoisty stan równowagi. Opisana postawa jest gwarantem satysfakcji płynącej z wykonywanej pracy i zabezpiecza edukatora przed wypaleniem zawodowym.
On the need to form moral convictions
Authors: Śliwerski Bogusław
Published: July 2024

Autor poszukuje w teoriach wychowania odpowiedzi na pytanie, w jakim stopniu są aktualne i potrzebne badania kształtowania przekonań moralnych dzieci i młodzieży w toku edukacji szkolnej? Zdaniem badacza transformacja ustroju społeczno-politycznego w 1989 roku sprzyjała pominięciu tak kluczowego fenomenu dla jakości wychowania, jakim są przekonania moralna. Trudność sprawia odróżnianie przekonań moralnych od światopoglądu i opinii moralnych. Przyjętą przez autora metodą badań jest analiza treści rozpraw z nauk społecznych, których autorzy podejmowali problem wychowania moralnego. Uzasadnia zarazem potrzebę powrotu pedagogów do powyższych kwestii, by edukujący dzieci w świecie narastających kryzysów moralnych odnaleźli w sobie odwagę do ich wychowywania.
The salesian society in the face of educational challenges in the years 1918-1939
Authors: Niewęgłowski Jan
Published: July 2024

After regaining independence in 1918 Poland commenced the long reconstruction process of state structures. The legacy of three seizures very much hindered this process. The Salesian Company, with the society as a whole, joined into creating missing school and protective structures. To 1918 Salesians could only to carry one's charisma out only in the Austrian annexed territory. One of the first activities of the Company after 1918 was opening secondary modern schools. It was being made at the request of authorities and the Polish society. Majority of schools of this type came into existence in the twentieth years. Some of them contended with many problems, like appropriately prepared staffs or financial problems. In spite of many problems they were pleased with rather a good opinion in the Polish society, facilitating for substantial amount of Polish young people getting the secondary education.
Duchowość ignacjańska w edukacji
Authors: Marek Zbigniew
Published: July 2024

W literaturze przedmiotu występują różne definicje terminu „duchowość”. Przyjmuje się, za jego pośrednictwem człowiek wyraża swe myśli, mowę, oceny, dążenia, twórczość, a także chęć przekraczania barier własnej ograniczoności. Wobec istotnych różnic w objaśnianiu, czym jest duchowość, przyjmuje się, że jest to termin prosty i niedefiniowalny o nachyleniu antropologiczny. Za jego pośrednictwem różne grupy społeczne zmierzają do objaśniania egzystencji człowieka dążącego do życia, szczęścia oraz miłości, czym nadaje jego życiu określony styl. Pośród wielu form życia wyrażających ludzką duchowość wymienia się duchowość ignacjańską (jezuicką). Jej inicjatorem jest założyciel zakonu św. Ignacy Loyola. Charakteryzuje ją wizja człowieka związanego z Trójjedynym Bogiem więzami miłości. Do praktyki codziennego życia wprowadzał ją metodą ćwiczeń duchowych. Jezuici spotykając się z jej skutecznością w życiu ascetycznym podjęli próby przeniesienia jej na płaszczyznę edukacyjną. W efekcie tych wysiłków wypracowano charakterystyczny dla jezuitów model edukacji, w którym ważną rolę pełnią zaczerpnięte z duchowości ignacjańskiej terminy: „magis” i „cura personalis”. Nadto na bazie duchowości ignacjańskiej opracowano teorię pedagogiki towarzyszenia.
Lithium in Drinking Water and its Potential Impact on Mental
Health: A Review
Authors: Bjørklund Geir , Storchylo Olha
Published: July 2024

This review explores the relationship between lithium in drinking water and
mental health, a subject that has garnered increasing attention in investigations. Lithium,
a metal with a well-established role in psychiatric medications, is found in trace
amounts in drinking water, and studies suggest its potential correlations with lower rates
of suicide and certain psychiatric disorders. However, these correlations do not imply
causation, necessitating an examination of the underlying mechanisms. Lithium concentrations in drinking water vary globally, presenting challenges in establishing a universal
threshold for “high” or “low” levels. Additionally, the optimal dosage for potential mental health benefits remains uncertain. Lithium is not considered an essential nutrient, and
supplementation should be approached with caution due to possible toxicity risks, emphasizing the importance of medical supervision. The lack of causation and ongoing
need for further investigation underscores the importance of cautious interpretation and
transparent communication in navigating this evolving field.
Computational Analysis of Marburg Virus Envelope Glycoproteins: Insights from Bioinformatics and Genomics
Authors: Polanco Carlos , Huberman Alberto , Uversky Vladimir N. , Rios Castro Martha , Becerra-Luna Brayans , Lemus Enrique Hernandez , Pimentel-Hernández Claudia , Martínez-Garcia Mireya , Buhse Thomas , Juárez Cynthia Karen Gutierrez , Alarcon Gilberto Vargas , Corona Gabriela Calvo-Leroux , Roldan Gomez Francisco J. , Díaz-González Juan Luciano , Martinez-Memije Raul , Flores Ch Pedro L.
Published: July 2024

Background:

Marburg virus (MARV), which is spread by one species of fruit bats, can
cause deadly Marburg virus disease (MVD, also known as Marburg hemorrhagic fever, MHF),
which is a severe form of viral hemorrhagic fever with symptoms similar to Ebola. MARV is considered
to be very dangerous, and there are no approved vaccines or antiviral treatments for Marburg
disease.

Objective:

Computational studies were conducted to comprehend the envelope glycoproteins GP1
and GP2 expressed by the Marburg virus.

Methods:

Determination of the predicted intrinsic disorder predisposition of each glycoprotein sequence
(PIDP) and the Polarity Index Method Profile 3.0v (PIM 3.0v) using genomics software and
multiple computer algorithms, several of which have been specifically designed for this purpose.

Results:

The PIM 3.0v and PIDP profiles showed different MARV envelope glycoprotein patterns.
These patterns revealed structural and morphological commonalities.

Conclusions:

Our computer systems were able to identify MARV envelope glycoprotein isolates
using the PIM 3.0v profile, and they suggest that they can be used as a first-step filter for identifying
them from databases or building synthetic proteins.
Aspects of immunology and management of post-splenectomy patients
Authors: Srikandi Ni Made Putri Rahayu , Suardamana Ketut
Published: July 2024

The spleen is the largest lymphatic organ in the body and plays an important role in fighting infection. It works to remove micro-organisms and their products circulating within the bloodstream and produce antibodies to enhance the immune response. The spleen is an intraperitoneal organ that performs vital haematological and immunological functions. It maintains both innate and adaptive immunity and protects the body from microbial infections. Splenectomy is associated with an impairment in immunoglobulin production, antibody-mediated clearance, and phagocytosis leading to an increased risk of infection and sepsis. Overwhelming post-splenectomy infection (OPSI) is a syndrome of fulminant sepsis occurring in splenectomized (asplenic) individuals that is associated with high mortality and morbidity. Early identification of the at-risk patient, early blood cultures before antibiotic administration, and sepsis bundles should be utilized in these patients. Prompt management and aggressive treatment can alter the course of disease in the at-risk splenectomized patient. Overwhelming post-splenectomy infection can be prevented through vaccination and patient education.
Origin of Gravity Lows South of the 85∘E Ridge (Central Basin of the Indian Ocean)
Authors: Bulychev Andrei , Dubinin Evgenii , Ivanenko Aleksandr , Levchenko Oleg , Veklich Ilya , Kosnyreva Mariya , Shaikhullina Anzhela
Published: July 2024

The 85∘E Ridge associated by the free-air gravity low into a meridional orientation. However, there are two gravity lows south between of 4∘N and 3∘S the nature of which remains a subject of discussion. This article presents the results of density and magnetic modeling based on the data of the expedition SO258/2 with RV Sonne. An analysis of the modeling results with seismic data showed that the nature of gravity lows is associated with the process of serpentinization, and these lows are not a continuation of the 85∘E Ridge.
Kearifan Lokal dan Kesetaraan Gender dalam Keluarga Etnis Dayak
Authors: Sara Sabina , Widiarti Febi , Musa Dahniar Th. , Junida Dwi Surti
Published: July 2024

The study aims to explore the local wisdom of the Dayak community in relation to the concept of gender equality in everyday life within the family of Dayak communities. This research uses a qualitative method approach. Aim to dig and understand the meanings associated with local wisdom and gender equality in the family. From the qualitative methods the researchers collected data through observations carried out directly in the Pontianak town of Ambawang. The data collection is also an in-depth interview with several Dayak ethnic families. The process of data analysis is done by recording field notes, then collecting, classifying the data to interrelate. The results of this study show that the cultural values and traditional knowledge of the Dayak ethnic community towards women in Dayak societies are of paramount importance, by showing that gender equality and recognition of the role of women can contribute to the sustainable development and well-being of societies. The results of this study provide an overview of gender equality practices based on local wisdom of the Dayak community, which differs from the concept of genders equality in general. The implications of this discovery can give a deeper understanding of the local culture and wisdom of a society can shape patterns of relationships and gender distribution in the family.
Risk Assessment and Mitigation Strategies for Landslides Triggered by Earthquakes
Authors: Huang Ying
Published: July 2024

This paper primarily investigates the mechanisms of landslides triggered by earthquakes, by analyzing the propagation characteristics of seismic waves under various soil and topographical conditions, and assessing their impact on slope stability. The study utilizes GIS and remote sensing technologies combined with field survey data to establish a comprehensive earthquake-induced landslide risk assessment model. It further discusses engineering and management strategies to mitigate such geological disaster risks, aiming to provide more effective disaster prevention and response measures in the field of civil engineering.
“Essential Security Interest”: How Did WTO Interpret?
Authors: Wang Ziyi , Qin Zihan
Published: July 2024

The world is facing a new security crisis—with the development of technology, national interest has been expanded from military to oceans, polar regions, outer space, and networks, as well as to new fields such as artificial intelligence and big data. And there will be a great possibility for states to invoke the “Security Exception” clause to exempt themselves from WTO obligations. Following the interpretation approach of the WTO Panel, there is no technical barrier to giving an expansive interpretation of the ESI. However, the Panel should cautiously examine it in case of abuse.
DEVELOPMENT OPTIMIZATION OF SORAFENIB-LOADED PLGA NANOPARTICLES GUIDED BY IN SILICO COMPUTATIONAL TOOLS
Authors: PARIDA GNYANA RANJAN , PATTNAIK GURUDUTTA , BEHERA AMULYARATNA , SAHOO SURAJ , MOHANTY DIBYALOCHAN
Published: July 2024

Objective: The purpose of this study was to develop, characterize, and optimize sorafenib-loaded Poly (lactic-co-glycolic acid) PLGA polymeric nanoparticles for prolonged delivery of sorafenib for improved hepatic cancer treatment
Methods: The drug-excipient interaction was explored by molecular docking studies within silico tools. The drug-loaded polymeric nanoparticles were prepared by single emulsion solvent evaporation method using box-bhenkan design and characterized for particle size, zeta potential, and entrapment efficiency. Shape and surface morphology was analysed by Transmission Electron Microscopy (TEM). In vitro drug release study was performed by using a diffusion membrane.
Results: The docking analysis inferred that the drug has interacted well with PLGA and PF-68, which could prevent the drug crystal formation. The optimized polymeric nanoparticles had a particle size of 175 nm, Entrapment Efficiency (EE) of 85.1% and zeta potential of-23.8mV were found to be within 95% of CI of the predicted value, which is acceptable. TEM studies showed that the formed polymeric nanoparticles were smooth, spherical in shape and uniform in size. In vitro drug release study of optimized formulation showed extended release for sorafenib.
Conclusion: Based on the computational studies and in vitro release studies, the developed Sorafenib loaded in PLGA nanoparticles could be a promising formulation in oral drug delivery for the treatment of liver cancer.
APPLICATION MEAN CENTERING RATIO SPECTRA METHOD FOR TERNARY MIXTURE OF DEXTROMETHORPHAN HBr, DOXYLAMINE SUCCINATE, AND PSEUDOEPHEDRINE HCl IN TABLET PREPARATIONS
Authors: TARIGAN RIDA EVALINA , FAISAL HENDRI , LASE IMAN KRISTIAN , HAFIFAH SAFURA PUTRI
Published: July 2024

Objective: The aim of this research is to apply the mean Centering Ratio Spectra (MCRS) method for a ternary mixture of Dextromethorphan Hydrobromide (DE), Doxylamine Succinate (DO), and Pseudoephedrine Hydrochloride (PS) in tablet preparations.
Methods: The absorption spectra of DE (40-430 μg/ml), DO (20-430 μg/ml), and PS (230-630 μg/ml) were scanned in the 200-400 nm range. DE determination involved dividing DE spectra by PS (430 μg/ml) and mean-centered the ratio spectra. DO spectra were divided by DE (40 μg/ml) to obtain mean-centered ratio spectra. The mean-centered ratio spectra for PS were obtained by dividing the scanned spectra of its prepared solutions by the standard spectrum of DE, which had a concentration of 70 μg/ml.
Results: Method validation parameters, including linearity, accuracy, precision, limit of Detection (LOD), and limit of Quantification (LOQ), were assessed. The results indicated linearity values of 0.9988, 0.9992, and 0.9998, respectively, for DE, DO, and PS. Accuracy: 99.84%, 100.15%, and 100.33%, respectively, for DE, DO, and PS. Precision: 0.53%, 0.54%, and 0.74%, respectively, for DE, DO, and PS. lOD: 1.85 μg/ml, 2.09 μg/ml, and 1.56 μg/ml, respectively, for DE, DO, and PS. lOQ: 6.19 μg/ml, 6.97 μg/ml, and 5.22 μg/ml, respectively, for DE, DO, and PS. All validation method parameters meet International Conference of Harmonization (ICH) validation requirements.
Conclusion: The MCRS method can be applied for the simultaneous ternary mixtures of DE, DO, and PS in tablet preparations. Its successful application, combined with rigorous validation results, suggests its potential for adoption in routine pharmaceutical analysis, contributing to the advancement of quality control practices in the industry.
DEVELOPMENT OF LIPID-BASED VESICLES OF TERBINAFINE GEL FOR SKIN DELIVERY BY 32FULL FACTORIAL DESIGN
Authors: SARASWATHI T. S. , ROSHINI R. , DAMODHARAN N. , MOTHILAL M. , JANANI S. K.
Published: July 2024

Objective: Terbinafine is a poorly water-soluble and highly permeable allylamine antifungal (BCS-II) drug. In this study, we looked at the possibility of using ethosomes as vesicular lipid nanocarriers to enhance the transdermal delivery of terbinafine.
Methods: Using a 32 full factorial design, the ethosomal formulation with different soya lecithin and cholesterol concentrations was improved and optimized. The influence of independent variables, namely soya lecithin and cholesterol concentration in ethosomes was determined by estimating dependent variable including the particle size, polydispersity index, zeta potential, entrapment efficiency, and in vitro drug release. To improve the residence time of ethosomes on the topical application, the ethosomes were incorporated into the carbopol gel. 1% w/v of Carbopol 934 P gel-embedded Terbinafine ethosomes were used to study medication release and skin interactions.
Results: Optimized ratios of soya lecithin and cholestrol was used to prepare vesicles. Formulation had a particle size of 1207.39±2.71 nm, entrapment efficiency of 94.46±0.47%, and in vitro diffusion of 51.27±0.16%. It was found that the growth of fungus Aspergillus niger and Candida albicans were inhibited by Ethosomal Gel. However, ethosomal gel had more inhibitory activity on Apergillus niger compared to positive control.
Conclusion: The current study suggests that ethosomal vesicles may improve transdermal dispersion without causing skin irritation. Terbinafine-loaded ethosomes have the potential to be one of the most important transdermal application techniques for the treatment of fungi-related disorders.
GC-MS ANALYSIS AND IN SILICO APPROACHES OF INDIGOFERA PROSTRATA AND LANTANA CAMARA CONSTITUENTS FOR ANTI-ALZHEIMER STUDIES
Authors: INJETI NEELAM , GUBBIYAPPA KUMAR SHIVA
Published: July 2024

Objective: The present investigation explored the binding affinities of phytoconstituents present in Indigofera prostrata and lantana camara that acted as Anti-Alzheimer's drug. Also the phytoconstituents were identified by Gas chromatography–Mass spectrometry (GC-MS) against selected targets, i. e., β-amyloid and acetylcholinesterase (AchE).
Methods: I. prostrata seeds and leaves of l. camara were macerated using methanol as a solvent, then analysed for phytoconstituents through GC–MS. The Chromatogram revealed the presence of 14 in I. prostrata and l. camara 19 novel phytoconstituents. These phytoconstituents were explored for their Anti-Alzheimer’s effect by iGEMDOCK software against selected targets, namely recombinant human acetylcholinesterase β-amyloid (protein data bank ID: 2LMN).
Results: The docking analysis resulted in four and five phytoconstituents with the highest binding affinity towards the selected targets in I. prostrate and l. Camara, I, respectively. The bioactive compounds present in the methanolic extract of l. camara were, Heptane,4-ethyl-2,2,6,6-tetramethyl-‘N, N-Dinitro-1,3,5,7-tetrazabicyclo[3,3,1] nonane, Spiro[androst-5-ene-17,1'-cyclobutan]-2'-one,3-hydroxy-,(3. beta,17. beta.). ligPlot depicted hydrophobic bonds, hydrogen bonds, and their bond lengths in each of the in silico effective docking compounds, which were compared with their respective standards.
Conclusion: From the results obtained it was concluded that the in silico analysis using computational approaches might become a prospective novel compound against the selected targets in Alzheimer's disease.
ESTIMATION OF IN VIVO PERFORMANCE OF SULFAMETHOXAZOLE AND TRIMETHOPRIM FROM ORAL SUSPENSIONS USING IN VITRO RELEASE DATA FROM A MINI PADDLE APPARATUS
Authors: RUIZ-SEGURA JUAN CARLOS , RIOS-RODRÍGUEZ JOSE MANUEL , REYES-RAMÍREZ FELIPE DINO , VELAZQUEZ-SANCHEZ CESAR ENRIQUE , MEDINA-LOPEZ JOSE RAUL
Published: July 2024

Objective: To estimate plasma concentrations-time profiles of sulfamethoxazole (SMZ) and trimethoprim (TMP) from oral pediatric suspensions through in vitro data generated with a mini paddle apparatus and dissolution media of physiological relevance. Post-marketing evaluation of pediatric formulations is always necessary.
Methods: Dissolution profiles of SMZ/TMP were obtained with a mini paddle apparatus at 100 rpm and 200 ml of 0.1 N HCl (pH 1.2), pH 4.5 acetate buffer, and pH 6.8 phosphate buffer. The reference and three multi-source pediatric formulations were tested. Drugs were quantified by a UV derivative method. Dissolution profiles were compared with model-independent and model-dependent methods. Plasma levels were estimated with dissolution data and published in vivo information. Percent of prediction error (%PE) for Cmax and AUC0-inf at each condition was calculated.
Results: In all conditions, similar dissolution profiles were found excepting for TMP of C drug product at pH 1.2 (f2<50). With model-independent comparisons significant differences in in vitro release performance of SMZ and TMP from all multi-source formulations were found (*P<0.05). When comparing the hypothetical Cmax and AUC0-inf of both drugs with in vivo data PE<15% were found only with reference and one formulation at pH 1.2.
Conclusion: The mini paddle apparatus and dissolution media of pH 1.2 were the best conditions to estimate in vivo plasma concentrations of SMZ and TMP from reference. These settings seem adequate to evaluate in vitro performance of multi-source formulations. It is necessary to carried out human studies with the used fixed-dose combination formulations to correlate in vitro/in vivo data.
INNOVATIVE LIPIDIC NANOCARRIERS OF FLUTAMIDE ENHANCING ITS IN VITRO CYTOTOXICITY AND IN VIVO ORAL BIOAVAILABILITY: DESIGN, OPTIMIZATION, CHARACTERIZATION, AND PHARMACOKINETIC ASPECTS
Authors: A. ALI MOHAMED , MOHAMED MAGDY I. , M. EL-SAY KHALID , MEGAHED MOHAMED A.
Published: July 2024

Objective: the reduced oral bioavailability of Flutamide has hindered its effectiveness as a chemotherapeutic agent for prostate cancer treatment. Our study aimed to enhance FLUTAMIDE in vitro cytotoxicity and oral bioavailability via its incorporation into lipid nanocarriers that contained solid lipid (Precirol®) alone or in combination with anti-androgenic oils such as Saw Palmetto Oil (SPO) and Pumpkin Seed Oil (PSO).
Methods: we employed the Box Behnken Design (BBD) to optimize Flutamide-loaded nanocarriers, focusing on mean vesicular size, zeta potential, and entrapment efficiency.
Results: the optimized nanovesicles exhibited dimensions of 330.2 nm, a zeta potential of -43.1 mV, and an entrapment efficiency of 66.1%. Morphological analysis using Transition Electron Microscope (TEM) and Scanning Electron Microscope (SEM) confirmed the spherical shape of the nanovesicles. Differntial Scanning Calorimetry (DSC) thermograms and X-ray diffractograms indicated decreased crystallinity of encapsulated Flutamide compared to free Flutamide. In vitro cytotoxicity studies demonstrated enhanced effects against prostate cancer cells (PC-3) for optimized Flutamide-loaded nanocarriers containing the 2 anti-androgenic oils over both nanocarriers containing no oils and free Flutamide suspension. In vivo pharmacokinetic analysis in male rats showed increased oral bioavailability for flutamide-loaded nanocarriers with Cmax values of 559.35±41.79 ng/ml and 670.9±24.61 ng/ml for different formulations compared to the free flutamide suspension with a Cmax value of 281.4±94.33 ng/ml.
Conclusion: These findings support FLUTAMIDE oral bioavailability improvement through nanocarriers encapsulation, advocating its utilization in prostate cancer therapy and approving the additive anti-androgenic effect after its combination with SPO and PSO.
SYSTEMATIC DEVELOPMENT, OPTIMIZATION AND EVALUATION OF ASCORBIC ACID-COATED SUPER-PARAMAGNETIC IRON OXIDE NANOPARTICLES (SPIONS)
Authors: KHAN SAMEEA AHMED , SHARMA RAJESH
Published: July 2024

Objective: In this study, Ascorbic acid-coated Super-Paramagnetic Iron Oxide Nanoparticles (AA-SPIONs) were synthesized, optimized, and further evaluated.
Methods: The nanoparticles were synthesized using the co-precipitation method, optimized by Box-Behnken Design (Design Expert® software). The formulation was then characterized for several in vitro attributes such as particle size distribution, zeta potential, Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD), Differential Scanning Calorimetry (DSC), and Vibration Sample Magnetometry (VSM).
Results: An optimized formulation was designed and synthesized. It showed an average size of ~260 nm with 24 mV zeta potential. The small size and electrostatic stability suggested an even distribution of particles in the bloodstream. FTIR revealed the interaction of AA with iron oxide. XRD studies and DSC thermograms ascertained the crystallinity of the iron formulation complying that the particles behaved as a single-domain magnetic crystal. The glass transition temperature of the coated nanoparticles was found to be 135.463ºC. Vibration sample magnetometry displayed the saturation magnetization value to be 2.87 emu g‾1, which indicated the retained super-paramagnetic nature of the nanoparticles.
Conclusion: The results were in concordance with the aim of this research work.
Ecstatic Objects: Santiago de Compostela
Authors: Dorrian Mark , Bonet Miro Ana
Published: July 2024

Degree Show Catalogue from an ESALA MArch (Modular Pathway) studio ‘Ecstatic Objects: Santiago de Compostela’. Studio Leaders: Mark Dorrian and Ana Bonet Miro. 2019-2020.
Close Encounters: Berlin. Experiments with Data, Nature, and Collective Life in the Urban Milieu
Authors: Faed Andrea , Paredes Maldonado Miguel , Brooks Andrew , Green Jack
Published: July 2024

Degree Show Catalogue documenting an ESALA MArch (Modular Pathway) studio ‘Close Encounters: Berlin. Experiments with Data, Nature and Collective Life in the Urban Milieu’. Studio Leaders: Andrea Faed and Miguel Paredes Maldonado, with Andrew Brooks and Jack Green. 2023-2024.
Daire’s Airc, Vol. 1
Authors: Scott Iain , Bingham Mark
Published: July 2024

Degree Show Catalogue documenting the first year of a two-year ESALA MArch (Integrated Pathway) studio, ‘Daire’s Airc’. Studio Leaders: Iain Scott and Mark Bingham. 2023-2025.
Radical Harvest: Earth/Care/Reuse
Authors: Ferracina Simone , Khan Asad
Published: July 2024

Degree Show Catalogue documenting an ESALA MArch (Modular Pathway) studio ‘Radical Harvest: Earth/Care/Reuse’. Studio Leaders: Simone Ferracina and Asad Khan. 2023-2024.
island territories VII: Island Temporalities
Authors: Hawker Adrian , Bernie Victoria Clare
Published: July 2024

Degree Show Catalogue documenting the first year of a two-year ESALA MArch (Integrated Pathway) studio and an associated one-year MArch (Modular Pathway) studio, ‘island territories VII: Island Temporalities’. Studio Leaders: Adrian Hawker and Victoria Clare Bernie. 2020-2022.
Spider Web, Integration-Interconnection Perspective Amin Abdullah
Authors: Haidar Putri Bayu , Dzulfahmi A. Adib
Published: July 2024

The troublesome contradiction between science and religion, which originated during the Renaissance and was introduced to Indonesia during the colonial era, marked the beginning of the formation of scientific integration. The answer proposed by several colleges is the merger of science and religion in the realm of education. It is envisioned that scientific viewpoints would no longer be independent and open as a result of scientific integration. The purpose of this research is to learn about the idea and execution of Islam and science integration at UIN Sunan Kalijaga Yogyakarta. This study employs a descriptive qualitative methodology in conjunction with a library research strategy. According to the findings of the study, the notion of Islam and science integration at UIN Sunan Kalijaga Yogyakarta is an interconnected integration strategy espoused by Amin Abdullah in the concept of scientific integration Spider's Web. The implementation has reached the level of systematic integrative scientific development, beginning with the philosophical level and progressing to the operational level of curriculum preparation and learning processes, or the strategic level.
Delimitation of Jurisdiction and Powers of the Russian Federation and Its Federal Subjects: The Role of the Federal Subjects
Authors: Kuznetsov I. N.
Published: July 2024

The article considers the problem of the role of the constituent entities of the Russian Federation in implementing the mechanism for division of jurisdictions and powers between the Russian Federation and its constituent entities. The author provides a general description of this differentiation mechanism and analyzes its evolution. Now, the division of powers takes place mainly through federal laws. However, the adoption of these laws is within the jurisdiction of the Russian Federation and is carried out through a special procedure — the legislative process. Therefore, the author evaluates the role of constituent entities in the division of jurisdictions and powers mechanism through their role in federal legislation. The author identifies the main problems and formulates a few promising proposals aimed at strengthening the role of the subjects of the Russian Federation and increasing the degree of consideration of their regional interests in the division of powers.
Abuse of Law in International Arbitration
Authors: Maksimov D. M. , Pakshin P. K.
Published: July 2024

The article deals with the phenomenon of abuse of law in international arbitration that seems to be an extremely relevant subject for study due to the development of transnational economic relations. At the same time, various types of abuse in arbitration make us think about developing a certain classification of all cases of abuse of law. The purpose of this article is to comprehensively consider the types of abuse of law in international arbitration and the prospects for countering such abuses, as well as to develop a theoretical basis for such countering based on world experience. In this study, the delay in the process, challenging the competence of arbitration, abuse of information disclosure and exchange of documents, the transfer of the assets of debtor to affiliates or third parties, a fraudulent application for bankruptcy of the debtor, as well as lies to arbitrators and fake evidence were considered. At the same time, the article notes the problem of the lack of mandatory ethical standards in international arbitration and the insufficient powers of arbitrators in the process. The authors conclude that it is necessary to continue work on ethical codes of conduct. In addition, it is concluded that it is necessary to apply liability measures and “procedural sanctions”. In this regard, we are ready for regulatory changes and the implementation of the “ethical review”, that is necessary for positive changes in arbitration.
Constructivism in Postmodern Jurisprudence
Authors: Chestnov I. L.
Published: July 2024

The author of the article shows how they change of the late 20th and early 21st Centuries ideas about reality. Objectivism and naturalism are being replaced by constructivism and mentalism today. What is real in the social world is what is perceived as real and what is constructed by people. This paradigm is becoming dominant not only in sociology, but also in jurisprudence. So, in postclassical criminology, crime and criminality are considered not some objective reality, but the result of the activity of the legislator. However, radical constructivism, which does not take into account external circumstances or structural constraints, cannot be considered an adequate concept. The author formulates an approach that includes both the transcendent foundations of law and the constructivist activity of powerful subjects in the reproduction of law. At the same time, examples from criminology and the opinions of leading scientists from this discipline are given. The necessity of taking into account the historical and socio-cultural context is stated.
pengaruh pemberian campuran madu dan kuning telur terhadap kualitas spermatozoa,fertilitas dan daya tetas ayam sentul
Authors: Yustiti Aida , Husmaini Husmaini , Jaswandi Jaswandi
Published: July 2024

Madu dan kuning telur merupakan salah satu feed suplement yang mengandung antioksidan sangat tinggi. Penelitian ini bertujuan untuk mengetahui Kualitas Spermatozoa ayam jantan Sentul yang diberi madu dan kuning telur sebelum Inseminasi Buatan terhadap kualitas spermatozoa,fertilitas,dan daya tetas telur.Penelitian ini dilakukan menggunakan metode Rancangan Acak Lengkap Pola Faktorial dengan 3 kali ulangan.Faktor A pemberian madu padaayam jantan Sentul dengan 4 level yaitu 0 ml (kontrol),3 ml madu,5 ml madu, dan 7 ml madu.Faktor B pemberian kuning telur pada ayam jantan Sentul dengan 4 level yaitu 0 ml kuning telur (kontrol),3 ml kuning telur,5 ml kuning telur,dan 7 ml kuning telur.Hasil penelitian menunjukkan analisis statistik terdapat interaksi sangat nyata (P< 0,01) antara kombinasi perlakuan yaitu pemberian madu dan kuning telur terhadap volume semen (0,85ml),konsentrasi spermatozoa (3,92 x 109),motilitas spermatozoa (90,00%), abnormalitas spermatozoa(5,00%), fertilitas telur (91,67%),mortalitas embrio(7%),dan daya tetas telur(93%). Dari hasil penelitianÂ  dapat disimpulkan bahwa pemberian 5 ml madu dan 5 ml kuning telur yang terbaik
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Tapak Liman (Elephantopus Scaber L ) Terhadap Bakteri Shigella Dysenteriae Dengan Metode Difusi Cakra,
Authors: Zendrato Baby Cikita Lestari , Nasution Sri Wahyuni , Lubis Nursoleha , Silaban Saharan R
Published: July 2024

Penyakit disentriÂ  merupakan peradangan pada usus yang disebabkan oleh bakteri shigella dan dapat menimbulkan gangguan fisiologis tubuh sehingga penyakit iniÂ  menjadi masalah kesehatan yang perlu untuk diperhatikan. Daun Tapak Liman ( Elephantopus Scaber L ) mengandung senyawa flavonoid yang tinggi, fenol dan saponin yang dilaporkan memiliki antioksidan, antibakteri, antivirus dan antiradang. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak etanol daun tapak liman ( Elephantopus Scaber L ) Â sebagai antibakteri dan untuk mengetahui nilai kadar bunuh minimal untuk bakteri Shigella sp. Penelitian ini menggunakan rancangan penelitian True Experimental Post-Test Only Control Group Design dimana Daun Tapak Liman diekstraksi dengan metode maserasi dan diletakkan pada media MHA yang ditumbuhi oleh bakteri. Berdasarkan hasil uji statistic menggunakan uji regresi didapatkan nilai t hitung 4,336 > 2,178 sehingga terdapat pengaruh ekstrak Daun Tapak Liman dengan zona hambat sebesar 65,4%.
EFEKTIVITAS PRP TERHADAP PERUBAHAN PROFIL LIPID DARAH TIKUS PUTIH JANTAN (Rattus Norvegicus) DIABETES MELITUS YANG DI INDUKSI STREPTOZOTOCIN
Authors: Simarmata Hans Pangestu , Saragih Reyini Namora L. , Pasaribu Jelita Pebriani , Sitorus Josua Panangian , Chiuman Linda , Janice Janice
Published: July 2024

Diabetes melitus menjadi masalah penyakit di Indonesia akibat ketidakmampuan pankreas untuk memproduksi insulin sehingga proses metabolisme tubuh menjadi terganggu. Platelet Rich Plasma banyak diketahui menjadi pengobatan di berbagai bidang kedokteran karenaÂ  mengandung banyak faktor-faktor pertumbuhan (GFs) yang berguna untuk memicu pertumbuhan, regenerasi jaringan, dan sel. Penelitian ini dilakukan untuk mengetahui efektifitas PRP dengan dosis 0.5, 1.0, dan 1,5 ml/kg BB terhadap perbaikan profil lipid. Penelitian ini menggunakan metode eksperimental dengan pembuatan PRP dilakukan dua kali sentrifugasi, selanjutnya dibagi kepada Â masing-masing perlakuan tiap kelompok diberikan sebanyak dua kali seminggu selama tiga minggu. Uji Shapiro-wilk digunakan untuk data berdistribusi normal dilanjutkan uji Kruskal-Wallis diikuti dengan analisa Mann-whitney dengan nilai signifikan P < 0.05, yaitu terdapat pengaruh pemberian PRP dengan perbaikan kadar profil lipid. Dosis PRP 0.5 ml/kg BB memberikan efek perbaikkan profil lipid kecuali kadar HDL dan dibutuhkan dosis PRP yang lebih tinggi untuk meningkatkan secara signifikan kadar HDL dibandingkan dengan kelompok kontrol.Â Â Â
Accumulation of Chrom (Cr) Contaminant in Rice Plant Around The Area Opak River Flow, Bantul Regency
Authors: Laoli Boris Marselius Sevendo , Kisworo Kisworo , Raharjo Djoko
Published: July 2024

Development of the leather tanning industry in the village of Banyakan, Piyungan, Bantul had a negative impact on the environment. The industrial waste from the leather tanning plant mixed with Cr metal enters the Opak River and is distributed to various places. River water is used as irrigation water which carries heavy metals that result in the accumulation of soil and plants, as well as another biota. The purpose of this study was to determine the profile and level of chromium accumulation in plants along the Opak River. The study was conducted at 6 stations in 6 different districts consisting of samples of irrigation water, sediment, stem roots, leaves, and rice plants. Heavy metal analysis on the sample was carried out using the AAS (Atomic Absorption Spectrophotometry) method. The results of the analysis of heavy metal concentrations that are distributed to the environment show that the plants that are the highest are 2,470 ppm, then sediment is 1,161 ppm, and irrigation water is 0.235 ppm. The highest accumulation of heavy metal Cr in the planting section of rice was consecutively in the grain > leaves > roots > stems. Results of the analysis of the BCF value of rice plant were categorized as a moderate accumulator plant, while the analysis of the TF value of rice plant was categorized as a phytoextraction plant. Health risk analysis HQ > 1, which means that rice from all stations is hazardous to health. Rice and water samples exceeded the established quality standard threshold, except for sediment which was still at a critical level.
PENGARUH SUBSTITUSI TEPUNG KULIT BIJI KAKAO PADA SOFT COOKIES TERHADAP KANDUNGAN GIZI DAN DAYA TERIMA KONSUMEN ANAK USIA SEKOLAH DASAR
Authors: Medita Havana Zahra , Rusilanti Rusilanti , Sukmawati Dalia
Published: July 2024

Penelitian ini bertujuan untuk menganalisis pengaruh substitusi tepung kulit biji kakao pada soft cookies terhadap kandungan gizi dan daya terima konsumen anak usia sekolah dasar. Sampel dalam penelitian ini adalah soft cookies subtitusi tepung kulit biji kakao dengan tiga perlakuan, yaitu persentase 10%, 20%, dan 30%. Penelitian ini dilakukan dengan tahapan awal adalah pengujian proksimat dari kandungan gizi soft cookies  dan pengujian organoleptik yang dilakukan oleh 20 orang panelis tidak terlatih siswa SD Bani Saleh 1 dan 20 orang panelis tidak terlatih siswa SDN Margahayu VIII dengan aspek penilaian meliputi aspek rasa, warna, aroma, dan tekstur. Hasil dari data uji proksimat menunjukkan bahwa soft cookies yang sudah memenuhi persyaratan mutu standar nasional kandungan gizi adalah kadar protein dan kadar lemak. Hasil dari data uji Friedman menunjukkan bahwa soft cookies  yang banyak disukai siswa dan siswi SD Bani Saleh 1 adalah soft cookies dengan persentase substistusi 10% dengan nilai rata-rata aspek rasa 3,80, aspek aroma 3,50, dan aspek tekstur 3,60. Sedangkan dari data uji Friedman menunjukkan bahwa soft cookies yang banyak disukai siswa dan siswi SDN Margahayu VIII adalah soft cookies dengan persentase substistusi 30% dengan nilai rata-rata aspek rasa 3,60 dan aspek tekstur 3,65. Kesimpulan pada penelitian ini bahwa formula terbaik dari soft cookies substitusi tepung kulit biji kakao berdasarkan uji organoleptik di dua sekolah dasar dan uji proksimat yang telah dilakukan adalah soft cookies dengan substitusi 10%.
Pemanfaatan Tumbuhan Herbaceous Sebagai Bioindikator Pencemaran Udara dengan Pengamatan Mikroskopis
Authors: Misya Meilyn , Prasetya Johan Danu
Published: July 2024

Udara merupakan komponen lingkungan dan sumber daya esensial yang menopang berbagai kehidupan makhluk hidup. Kualitas udara secara langsung dapat memengaruhi ekosistem, dan keseimbangan planet kita. Dewasa ini, peningkatan terhadap degradasi lingkungan telah mendorong kesadaran untuk memulai inisiatif dalam menjaga kualitasnya. Salah satu metode yang dapat dilakukan ialah dengan monitoring menggunakan bioindikator. Penelitian ini dilakukan untuk menentukan dan membandingkan kualitas udara di dua tempat berbeda yakni di kawasan permukiman Mancasan Lor dan kawasan taman timur Kampus I UPN â€œVeteranâ€ Yogyakarta menggunakan tumbuhan Rhoe discolor. Metode yang diterapkan adalah studi literatur, sampling dan pengamatan mikroskop di laboratorium. Sampel dengan jumlah stomata terbuka lebih banyak diasosiasikan dengan kualitas udara pada lingkungan yang masih terjaga.
Identifikasi Jenis Dan Karakteristik Sarang Lebah Madu Tanpa Sengat (Stingless Bee) Di Peternakan Lebah Simpur Desa Kecapi
Authors: Rudini Mahmud , Monita Dwi Niken Kristyanti , Kuswanto Eko , Listiana Ika
Published: July 2024

Peternakan lebah madu Simpur merupakan peternakan yang mengusung gaya wisata edukasi yang berada di kaki gunung Rajabasa Kalianda Lampung Selatan. Lebah madu tanpa sengat (Stingless Bee) memiliki peran penting dalam penyerbukan tanaman dan pelestrian lingkungan. Lebah tanpa sengat dalam melindungi dirinya hanya menggunakan gigitannya sebagai pertahanan terhadap serangan musuh. Penelitian ini bertujuan untuk mengetahui keanekaragaman jenis lebah tanpa sengat dan menganalisis karakteristik dari sarang lebah madu tanpa sengat yang terdapat di peternakan lebah madu Simpur desa Kecapi. Metode penelitian yang digunakan adalah survei eksploratif. Data yang dikumpulkan terdiri dari pengamatan secara langsung lebah dan karakteristik sarang lebah tanpa sengat yang ditemukan, mengumpulkan sampel lebah dan mengidentifikasinya. Identifikasi lebah tanpa sengat dilakukan melalui analisis morfologi.  Hasil dari penelitian menunjukkan 4 spesies lebah madu tanpa sengat yang berada di kawasan peternakan lebah madu Simpur, Desa Kecapi Kalianda Lampung Selatan yaitu, Heterotrigona itama, Lepidotrigona terminata, Tetrigona apicalis, dan Geniotrigona thoracica. Karakteristik sarang lebah tanpa sengat terbuat dari resin dengan pembagian ruangan yang terdiri dari bagian pintu masuk, pot madu dan pot bee bread dan sel-sel anakan.
Pola Sebaran Cemaran Krom (Cr) Pada Air, Sedimen, Dan Tanaman Air Di Bagian Hilir Sungai Opak
Authors: Elvina Wendy , Rahardjo Djoko , Kisworo Kisworo
Published: July 2024

Aktivitas penyamakan kulit yang berada di kawasan industri Piyungan, menggunakan logam berat krom (Cr) sebagai bahan utama dalam proses penyamakan kulit sehingga telah terjadi pencemaran logam berat kromium di sepanjang aliran Sungai Opak. Selain berdampak pada perairan, krom juga akan terdistribusi pada sedimen maupun biota pada Sungai Opak terkhususnya tanaman air yang memiliki sifat fitoremidiasi. Penelitian ini bertujuan untuk mengetahui pola sebaran cemaran krom pada sepandang aliran Sungai Opak di bagian hilir dengan menggunakan komponen air, sedimen, dan tanaman air. Penelitian dilakukan pada 5 titik uji pada bulan April, Mei, dan Juni. Kemudian, dianalisis kadar krom menggunakan metode AAS (Atomic Absobtion Spectrophotometer), dan diuji ANOVA. Dari hasil uji menujukkan bahwa Sungai Opak telah tercemar logam berat kromium dengan sebaran cemaran tertinggi pada sampel sedimen kemudian diikuti dengan sampel tanaman kangkung air (Ipomoea aquatica Forsk) dengan rerata 0,210 mg/L dan diikuti dengan sampel tanaman enceng gondok (Eichornia crassipes Mart. Solms) dengan rerata akumulasi sebesar 0,152 mg/L.
Komposisi, Keanekaragaman Dan Rasio Kelamin Ikan Elasmobranchii Asal Sungai Kakap Kalimantan Barat
Authors: Candramila Wolly , Junardi Junardi
Published: July 2024

Sifat biologi elasmobranchii seperti fekunditas rendah, pertumbuhan lambat, umur relatif panjang danresiko kematian tinggi pada semua tingkat umur menjadikannya kelompok ikan yang memiliki resiko kepunahan palingcepat dibandingkan kelompok lain. Tujuan penelitian ini untuk mengetahui komposisi, keanekaragaman dan rasiokelamin ikan elasmobranchii. Hasil penelitian dikoleksi sebanyak 31 spesies yang termasuk dalam 7 famili dan 238individu. Ikan pari ditemukan sebanyak 24 spesies dan 169 individu, sedangkan hiu tujuh spesies dan 69 individu.Indeks keanekaragaman ikan elasmobranchii antara 1,77-3,75.
Pengaruh Asam Giberelat (Ga3) Terhadap Perkecambahan dan Pertumbuhan Vegetatif Duku (Lansium Dookoo Griff.)
Authors: Murni Pinta , Harjono Danang Puspo , Harlis Harlis
Published: July 2024

Penelitian ini bertujuan mengetahui pengaruh Asam Giberelat (GA3) terhadap perkecambahan danpertumbuhan vegetatif duku. Perlakuan dengan pemberian GA3 pada beberapa konsentrasi yaitu 10 ppm, 50 ppm,100 ppm, 150 ppm, 200 ppm, 250 ppm, dan 0 ppm sebagai kontrol. Penelitian menggunakan Rancangan AcakLengkap (RAL) dengan empat kali ulangan. Pengamatan dilakukan terhadap waktu perkecambahan, dayaperkecambahan, tinggi tanaman, dan biomas (berat daun spesifik). Hasil analisis ragam menunjukkan bahwapemberian GA3 pada konsentrasi yang berbeda memberikan pengaruh berbeda nyata terhadap waktuperkecambahan dan daya perkecambahan (kecambah normal),. Berdasarkan hasil penelitian disimpulkan bahwa GA3dapat mempercepat perkecambahan biji duku, konsentrasi optimal untuk parameter perkecambahan yang diamatiadalah 100 dan 150 ppm.
Pattern of Macro benthos Succession in Sabang Waters after Tsunami
Authors: Rudi Edi , Fadli Nur
Published: July 2024

Research about succession of macro benthos on limestone substrate was conducted atthree sites (Klah Island, Gapang Beach and Gapang Mangrove) in the coral reef ecosystem of WehIsland from April â€“ December 2005. The selections of the sites are based on degradation of watersquality and coral reef condition. Limestone substrate as collectors were laid at 5 m waters depth ateach site, and further were taken after four and eight months. Succession pattern of macro benthoswas analyzed by Frontier Succession curve. The result shows that pattern of macro benthossuccessions were occurred significantly between locations and time. At site poor of natural coral reefcondition (Gapang Mangrove), succession pattern is in disturbance condition, while in Gapang Beachand Klah Island and Pulau Payung, which have good and fair coral condition, succession patterns aregoing in the direction of equilibrium condition. The result has indicated that waters quality is key factorfor macro benthos succession
Aktivitas Biostatik Torosflavon D Dari Cassia Torosa Terhadap Beberapa Cendawan Patogen Tanaman
Authors: Harizon Harizon
Published: July 2024

This research includes isolation of flavonoid Torosflavon D from Cassia Torosa, mediaformulation for pathogenic fungi growth, regeneration of pathogenic fungi, and bioactivity test of theisolated flavonoid on some pathogenic fungi. The flavonid bioactivities tests indicate that theTorosflavon D (5ppm) only effective to inhibit the radial growth of Fusarium oxysporum fsp.Lycopersici (48.75%). Statistical test (anova) indicates that concentration of the flavonid significantlyinhibit the fungi radial growth. Duncan test proves that 5 ppm concentration of Torosflavon D 5inhibits the growth of Fusarium oxysporum fsp. Lycopersici colonies optimally.
Local People And Primates In The Way Kambas National Park : Going Towards Co-Existence Or Conflict?
Authors: TRIANDIZA Teddy , Rustiati Elly Lestari
Published: July 2024

Kajian bekerja sama dengan Taman Nasional Way Kambas dilakukan untuk mengamatiperjumpaan dan gangguan primata di desa yang berdekatan dengan perbatasan taman nasional,Labuhan Ratu VI dan Labuhan Ratu VII. Survei lapangan dan penyebaran angket digunakan dalampengumpulan data. Perjumpaan dengan primata cukup tinggi. Di antara keberadaan empat primate,monyet ekor panjang dan beruk paling sering dijumpai secara langsung. Dua titik perjumpaanberdekatan dengan perkebunan singkong. Primata belum dianggap sebagai hama pengganggukarena adanya ancaman yang lebih besar dari gajah Sumatera dan babi hutan. Namun demikianpenemuan ini harus dijadikan pertimbangan untuk upaya konservasi yang berkaitan denganmasyarakat setempat dan primata di Taman Nasional Way Kambas.