bluuebunny/crossref_metadata_2025 huggingface dataset:
Pendampingan Program Tahsinul Qur’an Menggunakan Metode Baghdadi Di SMP Negeri 1 Padang Panjang
Authors: Nurfadhilah  , Martin Kustati  , Gusmirawati  , Rezki Amelia
Published: November 2024

Tujuan pengabdian melalui pendampingan program tahsinul Qur’an ini adalah untuk meningkatkan kemampuan peserta didik di SMP Negeri 1 Padang Panjang dalam membaca dan memahami tajwid bacaan Al-Qur’an, sehingga dalam kesehariannya nanti peserta didik dapat menerapkan ilmu membaca Al-Qur’an yang baik dan benar, mencakup makharijul huruf, dan ahkamul huruf. Minimnya kesadaran dari peserta didik untuk bisa membaca Al-Qur’an dengan baik dan benar terlihat dari kemampuan dan hasil bacaan Al-Qur’an yang diucapkan oleh peserta didik. Berawal dari permasalahan ini, kemudian diberikan solusi berupa pendampingan program tahsinul Qur’an menggunakan metode baghdadi, sebagai upaya melatih peserta didik dalam membaca Al-Qur’an. Pelaksanaan pendampingan ini menggunakan metodologi ABCD (Asset Based Community Development) yang berorientasi pada pemberdayaan kemampuan dari peserta didik agar mampu membaca Al-Qur’an dengan baik dan benar. Pada program tahsinul Qur’an ini diterapkan metode baghdadi yang didukung dengan teknik pengulangan agar lebih fasih dalam membaca Al-Qur’an. Dalam penerapannya metode baghdadi memberikan hasil yang signifikan terhadap kemampuan memabaca Al-Qur’an peserta didik. Hasil dari pendampingan tahsin ini dari sebelumnya peserta didik belum tepat dan benar dalam membaca Al-Qur’an sekarang sudah dapat membaca Al-Qur’an dengan baik dan benar sesuai kaidah ilmu tajwid yang mencakup ahkamul huruf, dan makharijul huruf.
Gambaran Psikologis Mahasiswa Laki-Laki Penyuka Anime Genre Yaoi (Fudanshi) di Kota Makassar
Authors: Saffana Mustafani  , Ridfah Ahmad , Sitti Hadjar Nurul Istiqamah
Published: November 2024

Fudanshi is a male fan of yaoi (Boy's love) anime. Fudanshi realize that their liking is a taboo in society, but still watch yaoi anime because they have various reasons, both from the psychological aspect of fudanshi, and from the closest people to fudanshi. This study aims to see the psychological picture and background of people around from fudanshi. The research method used in this research is qualitative with a case study approach. The data collection technique used in this research was interviews of one male student aged 19 years. The results of the research show that family background influences respondent to know and watch yaoi anime. From the cognitive aspect, in the form of views towards the yaoi anime, which does not have a big difference from other anime genres, from the affective aspect, there are feelings of fear and sadness regarding the public's response, while in terms of conation, there are changes in behavior before dan after getting to know the yaoi anime. The results of this research can be a source of information regarding the psychological picture of individuals who like the yaoi anime.
Pengaruh Perfeksionisme terhadap Ketidakpuasan Tubuh pada Mahasiswi di Kota Makassar
Authors: Miftahul Jannah  , Sitti Murdiana
Published: November 2024

Mahasiswi merupakan fase peralihan dari masa remaja menuju masa dewasa awal. Perubahan fisik yang terjadi pada masa ini membuat individu akan memperhatikan penampilannya. Selain itu juga adanya standar kecantikan pada masyarakat yang menuntut untuk menjadi sempurna dalam penampilan. Adanya standar ini menjadi faktor ketidakpuasan tubuh. Rasa ketidakpuasan yang muncul dikarenakan bentuk tubuh yang dimiliki tidak sesuai dengan standar tubuh ideal. Tujuan penelitian ini adalah untuk mengetahui pengaruh perfeksionisme terhadap ketidakpuasan tubuh pada mahasiswi di kota makassar. Responden dalam penelitian ini adalah mahasiswi aktif perguruan tinggi di kota Makassar berusia 18-25 tahun (N=349). Teknik pengumpulan data pada penelitian ini menggunakan skala perfeksionisme dan ketidakpuasan tubuh. Hasill analisis regresi sederhana menunjukkan bahwa terdapat pengaruh yang positif perfeksionisme terhadap ketidakpuasan tubuh dengan nilai signifikansi 0,00, p < 0,05. Penelitian ini berkontribusi pada mahasiswi agar dapat meminimalisir perfeksionisme yang dimiliki agar tidak mengalami ketidakpuasan tubuh, karena mempertimbangkan dampak negatif dari ketidakpuasan tubuh.
Dampak Dari Kurangnya Reseliensi Keluarga Dalam Penggunaan Gadget Pada Masa Perkembangan Remaja
Authors: Azhimah Rizka Nurtika
Published: November 2024

Resiliensi keluarga merupakan kemampuan suatu keluarga dalam memahami perkembangan anaknya dengan cara melakukan komunikasi yang baik antar anggota keluarga. Dalam hal penggunaan gadget, kurangnya resiliensi keluarga dapat berdampak negatif bagi para remaja. Resiliensi yang rendah cenderung memunyai kekurangan dalam pengawasan penggunaan gadget.  Tujuan dari penelitian ini adalah untuk mengetahui dampak dari kurangnya resiliensi keluarga dalam penggunaan gadget pada masa perkembangan remaja. Metode penelitiannya yaitu menggunakan pendekatan kualitatif, dengan metode studi kepustakaan. Secara umum gadget dapat mempermudah seseoran untuk berkomunikasi, memperluas jejaring sosial, dan bahkan mendukung pendidikan. Namun penggunaan gadget yang tidak terkontrol memiliki berbagai dampak negatif misalnya Adanya media sosial yang terdapat di gadget menimbulkan seseorang menggunakan lebih banyak waktunya untuk bermain gadget. Karena anak cenderung lebih memilih bermain dengan gadget nya dari pada bermain bersama teman sebayanya. Selain itu, aplikasi  yang terdapat didalam gadget menjadikan seseorang bersikap lebih egois (individualis). Sehingga mereka merasa bahwa dirinya tidak membutuhkan orang lain. Oleh karena itu Peningkatan resiliensi keluarga dalam penggunaan gadget sangat diperlukan untuk membantu mereka untuk dapat mengelola penggunaan gadget secara lebih efektif.
Implementasi Pembelajaran Kooperatif Tipe Teams Games Tournaments (TGT) dalam Meningkatkan Aktivitas dan Hasil Belajar PAI Pada Materi Al-Qur’an Surah At Tin di Kelas ICX SMP Negeri 2 Sirenja
Authors: Nurhaya Nurhaya
Published: November 2024

Penelitian ini bertujuan untuk mengetahui: apakah pelaksanaan pembelajaran PAI pada materi Al-Qur’an Surah At Tin melalui penerapan pembelajaran kooperatiftipe TGT meningkatkan aktivitas dan hasil belajar peserta didik. Penelitian ini merupakan penelitian tindakan kelas (classroom action research) yang dilakukan terhadap peserta didik kelas IXB  SMP Negeri 2 Sirenja. Terdiri dari 2 siklus yang setiap siklusnya meliputi perencanaan, pelaksanaan, pengamatan dan refleksi. Subyek penelitian ini adalah peserta didik kelas IXB SMP Negeri 2 Sirenja yang terdiri dari 26 peserta didik. Sumber data dalam penelitian ini adalah dokumentasi, hasil tes tertulis dan hasil observasi. Adapun tolak ukur keberhasilan dari penelitian ini adalah apa bila hasil belajar peserta didik mampu mencapai nilai rata-rata ≥75 dan banyaknya peserta didik yang memperoleh nilai ≥75 dengan ketuntasan klasikal 85%. Hasil penelitian yang diperoleh adalah sebagai berikut: hasil belajar pada pra siklus mencapai nilai rata-rata 72,23 meningkat menjadi 80,46 pada siklus I dan meningkat lagi menjadi 84,73 pada siklus II. Selain itu, ketuntasan belajar klasikal juga mengalami peningkatan dari pra siklus yang semula ketuntasan belajar klasikal 54 % meningkat menjadi 69,23%  pada siklus I dan akhirnya 92 % pada siklus II. Selain itu, terjadi peningkatan juga terhadap aktivitas pembelajaran. Hasilnya diperoleh dengan rata-rata prosentase yang semula hanya  53% pada pra siklus, meningkat menjadi 70%  pada siklus1 dan meningkat lagi menjadi 88% pada siklus 2 dengan criteria sangat baik. Dari hasil penelitian sudah memenuhi indikator keberhasilan yang diharapkan, maka proses penelitian dihentikan pada siklus II. Berdasarkan hasil penelitian, maka dapat diajukan saran bahwa strategi pembelajaran kooperatif tipe TGT dapat digunakan sebagai alternative untuk meningkatkan hasil belajar peserta didik, khususnya pada kemampuan kognitif dalam memecahkan masalah, keaktifan dan kerjasama dalam kelompok.
Ketimpangan Sosial dan Kemiskinan Pada Masyarakat Perkotaan
Authors: Muh. Watif  , Aulya Ramadhani.JT  , Jumiati  , Luthfiyah Syam Almazini Tahir  , Nurul Hikmah
Published: November 2024

The aim of this research is to investigate the factors causing social inequality and poverty in urban communities and identify effective coping strategies. The research method used is a qualitative literature study approach, where data is collected through searching and analyzing various literature sources relevant to the research topic. The results of the analysis show that social inequality and poverty in urban communities are influenced by various factors such as uneven economic growth, limited access to basic services, housing problems, and differences in access to education and health. The impacts of this inequality include health problems, low education, social instability, and deep economic disparities. To overcome social inequality and poverty in urban communities, a holistic response strategy is needed, including investment in inclusive education, strengthening basic infrastructure, community economic empowerment, and affordable housing policies. Collaboration between various stakeholders is also key in creating a more inclusive and sustainable urban society.
Pemikiran (Religius Rasional) Menurut Nasikh Ulwan Tentang Pendidikan Islam Serta Relevansinya Dengan Pendidikan Islam Kontemporer
Authors: Muhammad Afrizal Sauqi Billah  , Maragustam
Published: November 2024

Pendidikan Islam memiliki tujuan yang jelas dan spesifik, yakni menghasilkan anak yang lurus imannya, berakhlaq, bermoral, cerdas, terlatih fisik, serta berjiwa bersih. Abdullah Nashih Ulwan berpendapat bahwa pendidikan Islam harus berfokus pada pengembangan kualitas moral, spiritual, serta sosial pada anak. Ulwan mengemukakan lima metode pendidikan Islam, yaitu keteladanan, pembiasaan, nasihat, perhatian dan pengawasan, serta hukuman. Metode keteladanan melibatkan meneladani Nabi Muhammad SAW sebagai pemimpin dan teladan. Pembiasaan melibatkan peran pendidik dalam menuntun anak kepada tauhid murni, berakhlak, dan berjiwa mulia. Nasihat sangat efektif dalam mendidik anak agar terbentuk keimanan, psikis, sosial, serta moralnya. Pendidikan Islam yang berfokus pada pengembangan kualitas moral, spiritual, serta sosial pada anak sangat relevan dengan pendidikan Islam kontemporer. Pengembangan karakter anak juga penting, serta metode pendidikan yang digunakan harus efektif dan sesuai dengan tujuan pendidikan Islam. Pendidikan Islam harus berfokus pada pengembangan kualitas moral, spiritual, serta sosial pada anak. Metode pendidikan yang digunakan harus efektif dan sesuai dengan tujuan pendidikan Islam.
Hubungan antara Hardiness dengan Stres Akademik pada Siswa Kelas X di SMAN 8 Makassar
Authors: Luthfi Aqidatul Izzah , Alwi M. Ahkam , Andi Halima
Published: November 2024

Siswa SMA merupakan individu yang telah menginjak masa remaja sehingga dituntut untuk dapat mandiri dan memiliki pengambilan keputusan yang baik. Stress akademik merupakan respon individu terhadap tekanan internal maupun eksternal yang terjadi pada seseorang, respon tersebut dapat positif maupun negatif yang bereaksi terhadap fisik, psikologis, maupun emosi seseorang. Salah satu faktor yang mempengaruhi stress akademik adalah kepribadian hardiness. Penelitian ini bertujuan untuk mengetahui hubungan antara hardiness dengan stress akademik pada siswa kelas X di SMAN 8 Makassar. Penelitian ini mengambil 239 subjek dari siswa kelas X di SMAN 8 Makassar dengan metode simple random sampling. Penelitian ini menggunakan skala Perception of Academic Scale dan Occupational Hardiness Questionnaire, yang hasilnya dianalisis menggunakan uji korelasi Product moment pearson. Hasil penelitian menunjukkan terdapat hubungan negatif yang signifikan antara hardiness dengan stress akademik (r=-0,216). Implikasi penelitian ini adalah pengembangan kepribadian tangguh (hardiness) dapat digunakan sebagai model intervensi untuk mengurangi stres akademik pada siswa.
Engenharia para Crianças e Jovens: Uma abordagem STEAM para ensino de programação na educação básica
Authors: Santos Maria Fernanda dos , Santana Laura , Gomide Janaína , Azevedo João Pedro , Taqueuti Ana Júlia , Rezende Lucas , Villela Flávia , Nogueira Jefferson
Published: November 2024

Este artigo apresenta um relato de experiência de um projeto de extensão que desenvolveu um programa de ensino de programação usando conceitos de engenharia para alunos da educação básica. Foram realizadas oficinas e minicursos com escolas parceiras do projeto e público em geral, trabalhando temas que incluem energia sustentável, casas inteligentes, Indústria 4.0, Pontes Levadiças e Fundações. A avaliação dos alunos foi feita através de ferramentas interativas como Kahoot e Mentimeter, e o feedback dos monitores foi registrado em Diários de Bordo. Este trabalho se diferencia por focar na aplicação prática da abordagem STEAM e contou com a participação de mais de 400 alunos.
Ensino de Algoritmos para Pessoa com Deficiência Visual: Um Relato de Experiência no Ensino Superior
Authors: Ribeiro Filho José de S. , dos Santos Daniel S. , Macedo João Gustavo M. T. , Araújo Fabiola P. O.
Published: November 2024

A inclusão de alunos com deficiências em universidades brasileiras é amparada pela Lei n° 13.005/2014, que institui o Plano Nacional de Educação – PNE. Neste contexto, este artigo aborda um relato de experiência do ensino de Algoritmos a um aluno com cegueira total do curso de bacharelado em Ciência da Computação. As principais estratégias utilizadas no ensino da disciplina são detalhadas neste trabalho, como as atividades desplugadas realizadas, os mapas táteis desenvolvidos, o recurso de audiodescrição e o uso de ferramentas auxiliares, como leitores de tela. Elaborou-se um formulário para coleta de dados de avaliação das aulas, dos materiais didáticos e das ferramentas utilizadas. Ao final da disciplina, o aluno conseguiu obter as habilidades necessarias à resolução sistemática de problemas, ao mesmo tempo em que ele próprio destaca que as estratégias de ensino utilizadas serviram para deixá-lo mais motivado e confiante durante o aprendizado de Algoritmos, corroborando para a sua permanência no curso.
Oficinas de Robótica Educacional para estudantes em distorção idade-série: contribuições para aprendizagem cooperativa
Authors: Rodrigues Giulia D. S. , Aragón Rosane
Published: November 2024

Este estudo examina a distorção idade-série e a aprendizagem cooperativa, por meio da robótica educacional. Investigamos como a robótica pode melhorar a cooperação entre estudantes com distorção idade-série, que enfrentam altos índices de evasão escolar. Utilizamos a teoria da epistemologia genética e dados sobre tecnologias digitais na educação, adotando uma metodologia qualitativa exploratória. Os dados foram coletados em uma oficina de robótica, analisando interações segundo os princípios da aprendizagem cooperativa. Os resultados mostram que a robótica educacional beneficia o desenvolvimento da aprendizagem, aumentando a criatividade e a capacidade de resolução de problemas.
Medicinal Herbs
Authors: Acharya Amrit , Ghimire Gita , Shakya Prabin
Published: November 2024

This chapter explores the scientific research, supporting the multifaceted role of medicinal herbs and spices in our daily lives, focusing on their remarkable antimicrobial properties’ relevance in modern health and food industry. These natural wonders have been used for centuries in traditional medicine and culinary traditions. The bioactive compounds confer their antimicrobial abilities and the traditional practices that harness their potential for health and healing. Moreover, these herbs and spices not only enhance flavor but also serve as natural preservatives, safeguarding products from microbial contamination, and the future trends in this culinary field. Balancing the health and culinary facets, examine the impact of integrating these natural wonders into our diets, fostering not only well-being but also culinary delight, bridging the realms of human health and the food industry. This chapter also highlights challenges, opportunities, application, and modern prospective of herbs and spices in health and food industry.
Indonesia Spices Used in Global Cooking for Human Health
Authors: Mujianto Mujianto
Published: November 2024

Cooking spices produced on an industrial scale and derived from these spices have authentic Indonesian flavors; besides being nutritious, cooking spices from these spices is also healthy. One source of raw materials for this original Indonesian cooking spice is overfermented tempeh. The research results show that overfermented tempeh flour has great potential as a source of raw material for the cooking seasoning industry. Analysis of the main components of overfermented tempeh flour with 10 cooking spices circulating in Indonesia resulted in a very close similarity, namely three main components. The first main component is eight cooking spices.
Nature’s Impostors: Electrochemical Detection of Sildenafil in Natural Products
Authors: J. Castillo John
Published: November 2024

The electrochemical detection of sildenafil, a phosphodiesterase type 5 inhibitor used in the treatment of erectile dysfunction, has been of huge interest to researchers due to the wide prevalence of its adulteration in natural products. This review explores the chemical properties, pharmacological effects, and action mechanism of sildenafil, emphasizing its potent vasodilatory effects mediated through the inhibition of phosphodiesterase type 5. The illicit addition of sildenafil to natural products raises substantial health concerns, including severe cardiovascular events, especially in vulnerable populations. Analytical methods for the detection of sildenafil are critically reviewed, with a focus on chromatographic techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry, which offer high sensitivity and specificity. Electrochemical detection methods, including voltammetry and amperometry, are highlighted for their potential in providing rapid, cost-effective, and on-site analysis. The review discusses the challenges associated with electrochemical detection, such as interference from complex matrices and the need for highly selective electrode materials. Advances in nanomaterials, such as graphene and carbon nanotubes, are explored for their ability to enhance detection sensitivity and selectivity. Future directions include the development of portable electrochemical sensors and integrated analytical platforms for reliable and robust detection of sildenafil in natural products, ensuring consumer safety and regulatory compliance.
Development of Nanostructured BiVO4 Photoelectrodes for the Degradation of Pharmaceutical Pollutants in Wastewaters
Authors: Arunachalam Prabhakarn , S. Amer Mabrook , N. Shaddad Maged , M. Al-Mayouf Abdullah
Published: November 2024

Global environmental problems, such as energy shortages and water pollution, threaten sustainable development. In recent years, pharmaceuticals have been recognized as emerging water pollutants. Water splitting using photoelectrochemical (PEC) technology has attracted considerable attention for its eco-friendly and promising characteristics. Photoelectrocatalytic oxidation has been widely studied in order to remove them from contaminated water. This chapter describes recent advances in competitive photoelectrocatalytic integrated photoelectrodes utilizing BiVO4 and other cocatalytic materials. Further, we discuss the development of photoelectrocatalytic devices for the efficient degradation of pharmaceutical pollutants (ciprofloxacin, sulfamethoxazole, and tetracycline hydrochloride) in wastewater. This photoelectrode nanostructure is designed to capture more photons, reduce electron-hole recombination, and utilize more solar energy. Therefore, we examine the important properties of BiVO4-based materials for efficient degradation of PEC pollutants in this book chapter. Our book chapter discusses key challenges and future prospects in wastewater treatment and offers new insights.
Temporomandibular Disorders: Current Diagnosis and Treatment Methods
Authors: Tugce Gokdeniz Seyide , Irem Ozturk Barut Zehra , Buyuksungur Arda , Eray Kolsuz Mehmet
Published: November 2024

The term temporomandibular disorders is used as a collective term for a group of musculoskeletal disorders that involve pain dysfunction in the masticatory muscles, temporomandibular joints, and related structures. Patients with temporomandibular disorders usually present to clinics with pain, limitation, and noise in jaw movement. While clinical examination is considered the most important process in the diagnosis of temporomandibular disorders, imaging methods selected according to the cases, are also considered important aids in diagnosis. The use of artificial intelligence in the diagnosis of temporomandibular disorders is also becoming increasingly common. Current studies on this subject recommend the use of deep learning models to facilitate diagnosis and increase diagnostic accuracy. The etiology of temporomandibular disorders is quite complex and multifactorial. Due to this complex etiology, current studies support conservative multidisciplinary treatment methods including behavioral therapy, physical therapy, and pharmacotherapy. The role of osteotomy in the treatment of temporomandibular joint disorders is also very important. It is also stated that temporomandibular joint dysfunctions decrease after osteotomies such as sagittal splint osteotomy, which corrects occlusion disorders. The purpose of this chapter is to provide an overview of the latest developments in the etiology, pathophysiology, diagnosis, and treatment of temporomandibular disorders.
Optical Tools for Holographic Lens Design in Anidolic Solar Applications
Authors: Lloret Tomás , Morales-Vidal Marta , Pascual Inmaculada
Published: November 2024

This book chapter provides an overview of how holographic lenses (HLs) applied as anidolic systems (solar concentrators) have evolved to optimize the characteristics of current photovoltaic devices. The main parameters to be considered in the design of these HLs are described, such as average diffraction efficiency, acceptance angle, angular and spectral dependence, and the optimal number of HLs. In addition, the dynamic range of the material and the characteristics to multiplex different HLs with high diffraction efficiencies are emphasized. To this end, new strategies are proposed, such as the use of the exposure scheduling method (ESM) to improve the exposure times. This technique is compared to current techniques followed by researchers working in this field, such as the stacking of several photopolymer layers or considering a system of N holographic lenses. Finally, the advantages and disadvantages of current holographic photopolymers are compared.
Optimal Corrective Angle in Recent High Tibial Osteotomies
Authors: Deie Masataka , Yamanashi Yuki
Published: November 2024

High tibial osteotomy (HTO) is a traditional surgical procedure for medial-type osteoarthritis of the knee. Recently, the procedure has evolved into a type of knee-preserving surgery. Minor correction HTO aims for a tibial correction angle of ≤15 degrees, a femorotibial angle (FTA) of 171 degrees, a medial tibial plateau angle of ≤90 degrees, and a % medial axis (%MA) of 55%. We have achieved good short-term clinical results by preserving as much cartilage and meniscus as possible. These results show high patient satisfaction and good clinical outcomes. We propose a new HTO concept that combines minor correction with joint preservation to maintain good gait and quality of life (QOL), rather than solely focusing on pain relief through lower limb alignment correction. In Japan, where people are living longer, we suggest this new HTO concept for patients aged 50–60 years with osteoarthritis, followed by conversion to primary total knee arthroplasty (TKA) around age 80.
Impact of Traceable Volatile Organic Compounds Reference Gas Mixtures in the Urban Air Pollution Monitoring System
Authors: Ntsasa Napo , Mogashane Tumelo , Mashale Kedibone , R. Letsoalo Mokgehle , Mkhohlakali Andile , Tshilongo James
Published: November 2024

The monitoring of volatile organic compounds (VOCs) from industrial and ambient sources plays a critical role in air quality management, contributing data for legislative requirements. Emitted from sources such as biomass burning and power stations, VOCs contribute to ozone formation, which impacts environmental visibility, and promotes smog, acid rain, and ozone depletion. Various sampling and analysis methods are employed to monitor VOCs, relying on quality protocols to ensure data reliability. Calibration of VOC measurement equipment involves gas reference standards linked to the international system of units (SI) through primary methods like gravimetry. The objective is to elaborate the impact of these reference gas mixtures in the monitoring of VOC. This chapter focuses on the role of VOC reference gas mixtures in monitoring, emphasizing manufacturing methods, data comparability from proficiency testing schemes, and global data consistency. The key findings in this chapter highlight the real-time data analytics, machine learning algorithms for predictive modelling, and dispersion of sensor networks as the potential advancements in VOCs monitoring to improve capacity to identify and address new pollution patterns that will have significant impact on the improved public health protection and air quality management.
Review of Microbial Therapy
Authors: Suvorov Alexander
Published: November 2024

The human microbiome is an important integral part of the organism. This reflects on multiple molecular connections between the organs and microbiota, which is controlled by the innate immune system and makes the organism function properly as a holobiont. This explains the reasons behind the misfunction of the multicellular organism in cases of dysbiotic conditions. Any infection or pathology, including cardiovascular, gastrointestinal, or cancer diseases, is accompanied by dysbiosis. Microbial therapy with bacteria, fungi, or viruses grown outside the body and taken as a medicine or the drug interferes with the microbiota of the host. It is based on the ability of probiotic microbes to exclude a certain pathogen out of the organism employing the tools of antagonism or improve certain metabolic pathways due to the specific metabolic activity of therapeutic microbes. However, it is difficult to expect the longitudinal effect of such a therapy due to the exclusion of the exogeneous microbe by the host immune system. An autoprobiotic approach based on careful selection of indigenous bacterial strains as personal microbial medicine allows to avoid this problem. Here, we present an overview of different approaches for microbial therapy, making the emphasis on autologous microbial therapy by autoprobiotics.
Painless Aortic Syndrome in a Patient with Syncope and Globus Sensation: A Case Report
Authors: Rosenfeld-Barnhard Gavriel , Jackson Jessica R , Mendez Kendra A. , Schreyer Kraftin E.
Published: November 2024

Introduction: Aortic dissection is a devastating clinical entity with a variety of presentations and requires prompt recognition and management. To our knowledge this is the first reported case of a patient who presented with a globus sensation and was diagnosed with an aortic dissection prior to clinical deterioration. Case Report: The patient presented with an episode of near-syncope and globus sensation. Imaging studies revealed a type A aortic dissection with hemopericardium requiring emergent operative intervention. Unfortunately, the patient’s course was complicated by significant hemorrhage and periods of hypotension, and the family ultimately decided to pursue comfort care. Conclusion: Aortic dissections can present with diverse and elusive symptoms, which can mimic other more common conditions, potentially leading to misdiagnosis and delayed intervention
Severe Hyperkalemia in a Child with Vomiting and Diarrhea
Authors: Khan Abdullah
Published: November 2024

Case Presentation: A 13-month-old child with past medical history of congenital adrenal insufficiency presented to the emergency department with vomiting and diarrhea. Initially the child was noticed to have bradycardia with normal blood pressure. An electrocardiogram (ECG) showed tall T waves, broad QRS complex, and widened PR interval suggestive of severe hyperkalemia. The initial blood gas showed potassium of 10.7 millimoles per liter. The patient was started on calcium gluconate with immediate resolution of ECG changes. Further management with insulin, dextrose, and sodium olystyrene sulfonate led to normal potassium levels. Discussion: Hyperkalemia is a life-threatening condition in children, especially in those with congenital adrenal insufficiency. The ECG showed different changes as the levels of serum potassium levels increased ranging from tall T waves, wide QRS complex, increased PR interval to arrythmias. Immediate treatment with calcium gluconate in such cases has significant cardioprotective effect. It is important to recognize the ECG changes manifested by changes in serum potassium levels. Our patient had classic ECG changes manifested in severe hyperkalemia.
Sirtuin 1 Dynamic Interplay of IFI16 and STING Interferon-Stimulated Gene Regulate Hepatitis B Virus Replication
Authors: Li Di , Yu Qing Hua , Li Sha Sha
Published: November 2024

Background: Hepatitis B virus (HBV) infection remains a significant global health concern, affecting millions worldwide and often leading to severe liver diseases. Chronic conditions associated with HBV contribute to the development of liver fibrosis, a crucial prognostic factor necessitating urgent therapeutic strategies. Objectives: This study aims to elucidate the interplay between interferon (IFN)-inducible protein 16 (IFI16), Sirtuin 1 (Sirt1) (NAD-dependent deacetylase), and STING (Stimulator of Interferon Genes) in the context of HBV infection, focusing on understanding their roles in viral replication and innate immune responses. Methods: This study investigates the interaction between Sirt1 and IFI16 during active HBV replication using siRNA-mediated knockdown and co-transfection techniques. HBV replication is assessed following IFI16 silencing, and the synergistic inhibition of IFI16 and Sirt1 is evaluated. Western blotting, electrophoresis, and immunoprecipitation methods are employed to explore STING's role in DNA-mediated innate immunity and interferon-stimulated gene activation during viral infection. Results: While individual knockdown of IFI16 has minimal impact on HBV replication, with a reduction of less than 10%, dual inhibition of IFI16 and Sirt1 resulted in a significant reduction in viral replication by approximately 70%. This underscores the synergistic role of these proteins in the context of HBV infection. Furthermore, the study implicates STING as a promising therapeutic target for viral infections, shedding light on its regulatory role in innate immune responses and interferon-stimulated genes (ISGs). Conclusions: Our study reveals the complex interplay between IFI16, Sirt1, and STING in HBV infection, highlighting potential therapeutic targets. While in vitro findings offer valuable insights, in vivo validation and further exploration of broader pathway interactions are essential. Future efforts should prioritize translating these findings into clinical applications for HBV treatment.
Curcumin Induces MCF-7 Breast Cancer Cell Apoptosis Through miR-15a Alteration
Authors: Rezaeidian Jalal , Naseh Vahid , Entezari Maliheh , Ziyadi Hakimeh , Hashemi Mehrdad
Published: November 2024

Background: In recent years, the application of herbal compounds in cancer treatment has shown significant progress. Curcumin (CUR), a natural polyphenol, demonstrates potent anti-cancer effects against various cancers, including breast cancer (BC). Curcumin targets a range of molecular pathways, contributing to the inhibition of cancer cell proliferation, metastasis, and angiogenesis, and promoting apoptosis. Objectives: This study aimed to assess the effect of CUR on BC cells, focusing on alterations in the expression levels of Mir-15a and Bcl-2 through the apoptotic pathway. Methods: The cytotoxicity of CUR was evaluated using an MTT assay. Changes in the expression of Mir-15a and Bcl-2 genes were analyzed by real-time PCR, and cell apoptosis was measured using flow cytometry. Data analysis was conducted using SPSS. Results: The MTT assay results indicated that cell viability decreased as CUR concentration increased (5 – 25 µM). Real-time PCR results showed a significant decrease in the expression of Mir-15a and Bcl-2 (P < 0.05). Flow cytometry findings demonstrated that CUR treatment at the IC50 concentration for 48 hours induced apoptosis in 75.9% of MCF-7 cells. Conclusions: Our study provides a crucial foundation indicating that CUR induces apoptosis in MCF-7 cells by modulating the expression of Mir-15a.
The Role of Uterocervical Angle on Preterm Birth Incidence
Authors: Shirazi Mahboobe , Sina Mozhgan , Hantoushzadeh Sedigheh , Golshahi Fetemeh , Sahebdel Behrokh , Feizabad Elham , Amiriariya Zeynab , Roshani Moghaddam Hakime , Asadi Leila
Published: November 2024

Background: Preterm birth (PB) is associated with significant morbidities in surviving infants. Accurate prediction of PB is essential for effective prevention and management. Continuous monitoring of cervical parameters has shown utility in several studies. Objectives: This study aimed to investigate the role of the anterior uterocervical angle (UCA) in predicting the incidence of PB. Methods: A prospective, descriptive-analytic study was conducted with 165 pregnant women referred to the prenatal care clinic at Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran, in 2021 - 2022. Participants were selected through convenience sampling. Cervical parameters, including UCA, length, and width, were measured via vaginal ultrasound during each trimester. All women were followed until delivery to determine PB incidence. Data were analyzed using descriptive and analytical statistical tests, including the chi-square or Fisher’s exact test and the independent samples t-test or Mann-Whitney U test. Results: Among the participants, 12 (7.3%) experienced preterm delivery. Cervical length was significantly shorter in women with PB during the second trimester (32.58 ± 4.77 mm vs. 34.68 ± 3.80 mm, P = 0.042) and third trimester (30.00 ± 4.74 mm vs. 32.77 ± 3.88 mm, P = 0.022). The mean UCA in women with preterm delivery was higher than in those with term delivery during both the second (90.58 ± 17.21° vs. 88.66 ± 16.76°) and third (100.25 ± 14.56° vs. 98.89 ± 17.78°) trimesters (P > 0.05). A UCA greater than 105° in the second trimester had a sensitivity of 16.7% and specificity of 81.5% for predicting PB. In the third trimester, a UCA greater than 105° showed a sensitivity of 58.3% and specificity of 60.7% for predicting PB. Conclusions: This study emphasizes the importance of regular cervical parameter measurements throughout pregnancy. A UCA greater than 105° in the third trimester appears to be a potential predictor of PB.
The Impact of Color in Healthcare Environments: A Systematic Review and Research Agenda
Authors: Tabanejad Zeinab
Published: November 2024

: Color plays a significant role in shaping the atmosphere and experience within healthcare environments. This systematic review examines the existing literature on the effects of color in healthcare settings, aiming to provide insights into its influence on patient outcomes, staff well-being, and overall healthcare experiences. By synthesizing findings from various studies, this review identifies key themes, explores methodological approaches, and proposes a comprehensive research agenda to better understand the complex relationship between color and health outcomes. The review involved a systematic search of databases such as PubMed, Scopus, and Web of Science, as well as internet search engines including Google and Yahoo. The search focused on empirical studies, theoretical papers, and industry guidelines related to color in healthcare settings. Over 3 000 titles were screened, and relevant studies were critically evaluated for their methodological rigor and findings. A PRISMA form was used to extract the necessary information. The synthesis of existing literature highlights the importance of considering color selection, application, and environmental context in healthcare design to optimize patient care and enhance the well-being of both patients and healthcare providers. Although the existing literature underscores the importance of color in healthcare design, empirical evidence remains limited. Future research should aim to address these gaps by exploring the nuanced ways in which color influences health outcomes and by developing evidence-based guidelines for the application of color in healthcare settings.
What is the real-world impact of COVID-19 vaccines on community transmission?
Authors:   Parliamentary Office of Science and Technology, Vagnoni Cristiana
Published: November 2024

Real-world data shows that COVID-19 vaccines deployed in the UK are effective in protecting against SARS-CoV-2 transmission already after a single dose. Are all the other COVID-19 vaccines equally effective? What is the evidence on balancing between vaccinations and lifting restrictions?
Science Diplomacy
Authors:   Parliamentary Office of Science and Technology, Ledgerwood Emmeline , Bunn Sarah
Published: November 2024

A overview of science diplomacy, outlining its role in scientific collaborations and to support international diplomatic relationships, and a resume of recent developments.
Littérature et esthétique de la consommation
Authors: Letourneux Matthieu
Published: November 2024

Resume :En prenant appui sur une définition élargie de la relation esthétique intégrant en particulier les expériences esthétiques du quotidien, on peut identifier une multitude de dispositifs commerciaux et médiatiques visant à solliciter l’attention du public. Or, une telle bascule vers une esthétique de la consommation entraine des conséquences sur la définition de la littérature et sur le périmètre des objets susceptibles d’intéresser les études littéraires. C’est un tel élargissement tout à la fois du champ de l’esthétique et des objets de l’analyse littéraire que nous voudrions proposer dans cet article. Il s’agira de ressaisir la dimension culturelle et sociale de l’esthétique (et en particulier celle du champ élargi de la littérature) pensée dans cette perspective, en tenant compte de sa dimension historique, situant ses dispositifs dans des cadres sociaux, politiques et moraux. Il s’agira également d’aborder ses dispositifs à l’intersection des questionnements techniques, poétiques et culturels.
Artô in vitro
Authors: Cornille Jean-Louis
Published: November 2024

Resume :Le rejet par la NRF des premiers poèmes d’Antonin Artaud, en 1923, donna lieu à toute une correspondance entre le poète et Jacques Rivière que ce dernier publia l’année suivante en lieu et place des poèmes refusés. Dans la foulée de cette reconnaissance retardée, Artaud conçut un poème en prose qu’il intitula « La Vitre d’amour », dans lequel un étudiant amoureux lorgne à travers sa fenêtre une belle se dénudant, qu’il ne sait comment joindre. Lui viennent alors en aide, sur un mode fantastique, une bande d’auteurs admirés par lui, Hoffmann, Lewis et Nerval, lancés à la poursuite de la jeune femme. Ils ont en commun d’avoir été édités par un même éditeur, Pierre Mac Orlan, qui fait partie de cette même bande. On peut toutefois se demander si cette référence éditoriale n’éclaire pas une autre scène, dont Rivière et la NRF seraient les véritables sujets. Le plus étonnant est que, en rejouant les deux temps (échec suivi de succès) d’une entreprise (amoureuse ou artistique), ce poème semble rejoindre La Mariée mise à nu par ses célibataires, même, appelé encore Le Grand Verre, de Marcel Duchamp que celui-ci entama en réaction à un premier échec. Le poème d’Artaud vient illustrer à son tour ce mode de reconnaissance de l’artiste moderne, rejeté, avant d’être reconnu.
Obrazy holokaustu v bulharské poválečné literatuře
Authors: Mikulecký Jakub
Published: November 2024

The study deals with the theme of the Shoah in Bulgarian postwar literature, which includes both works of fiction (authors like Viktor Baruh, Salis Tadzher, Simcho Isakov etc.) published in the People’s Republic of Bulgaria (1946–1990), and literature of Bulgarian Jews in Israel (Albert Beni, Albert Mihael, Albert Varsano etc.). The article is an attempt to interpret the selected works (novels, novellas, short stories, poetry and memoirs) with regard to various discursive strategies that have changed and adapted to different socio-political contexts in both countries. The themes of the Shoah and the anti-Jewish policy of tsarist Bulgaria could take on diverse ideological functions depending on the context. Literature thus became an important component of various memory constructs in postwar Bulgaria and as well as in Israel.
Evaluasi Platform Elearning pada Matakuliah Metodologi Penelitian Menggunakan Model Evaluasi CIPP
Authors: Yanti Rini Fariska , Dewi Siska Miga
Published: November 2024

The problem in this study is the lack of student understanding in the online learning process through the e-learning platform in the Research Methodology course and the absence of an evaluation of the effectiveness of using the e-learning platform in the learning process. The purpose of this study is to determine the evaluation of the e-learning platform in the Research Methodology course using the CIPP evaluation model which includes Context, Input, Process, and Product. Overall, the results of this study indicate that the e-learning platform has a positive impact on Research Methodology learning. Although all aspects are in the good category, the percentage value of each aspect is still close to the lower limit of the category, so there is still room for further improvement to increase the effectiveness of learning as a whole.
Implementasi Manajemen dalam Pengembangan Perpustakaan Sekolah di SMAN Kualuh Selatan Labuhanbatu Utara
Authors: Aprilia Dinda , Harahap Nursapia , Faishal Muhammad
Published: November 2024

This study aims to accurately describe how school management and library development are implemented at SMAN 1 Kualuh Selatan, with a focus on the library's role as part of the educational process. The research employs a descriptive qualitative method, collecting data through in-depth interviews, direct observations, and documentation. Information was gathered from various informants, including the principal, library managers, teachers, and students, to provide a deeper understanding of school and library management. For data analysis, this study follows the steps outlined by Miles and Huberman: data reduction, data display, and conclusion drawing. The findings indicate that management at SMAN 1 Kualuh Selatan focuses on human resource management, budgeting and financing, as well as facilities and infrastructure, including the library. It was found that the school’s human resources are well-managed, though there are challenges in library development that still require improvements, particularly in collection and staffing. Supporting factors for library development include stakeholder collaboration, literacy activities, and government policies, while the primary constraint is the limited number of professional staff. This study concludes that while significant efforts have been made in library development at SMAN 1 Kualuh Selatan, there is still a need for improvements in resource qualification and collection management to ensure the library can optimally support the school’s educational goals.
Inference of Some Macroeconomic Variables on Nigeria Unemployment Rate
Authors: John David Ikwuoche , Saheed Salawu I. , Mary Adehi U.
Published: November 2024

This research investigates the impact of foreign direct investment (FDI), government expenditure (GOE), and inflation rate (IFR) on the unemployment rate (UPR) in Nigeria from 1985 to 2021 through Autoregressive Distributed Lag (ARDL) modeling approach. An initial assessment to test the significance of signals between each independent variable and UPR was performed using rolling correlation analysis. Subsequently, the bounds test methodology to examine cointegration among between the FDI, GOE, IFR, and UPR was performed. Additionally, the causal relationship between these economic variables was performed through the Error Correction Model (ECM) approach. The estimated ARDL model parameters stability was determined using the cumulative sum (CUSUM) of squares chart. The Augmented Dickey Fuller unit root test suggests that the variables are stationary at first differences (I(1)). The bounds test revealed that the variables are cointegrated at 1%, 5%, and 10% indicating a long run relationship between UPR and FDI, GOE, and IFR. The ARDL results indicates that at 5%, a unit increase in FDI at lag one have a long run significant decreasing impact on UPR by 19.96%. But in the short run, the FDI at lag one has a significant increasing effect on UPR by 7.23%. However, the CUSUM of square chart shows unstable parameter estimation based on the Akaike Information Criteria selected model, ARDL (1, 3, 0, 0).  The study concludes that UPR is being influenced by FDI in reducing UPR in the long run. Recommendation based on the findings is that FDI should be considered most important when policies are drafted for tackling the issue bordering UPR in Nigeria.
Hüsn ü Aşk’ta Renkler
Authors: Mete Nevin
Published: November 2024

Renk olarak tanımladığımız şey, gözümüze doğrudan ya da cisimlerden yansıyarak ulaşan farklı dalga boylarındaki ışığın, beyin tarafından yorumlanması sonucunda ortaya çıkan görsel duyumdur. Renk algısıyla ilgili duyumuz olan görme ise, gözün ışıkla yaptığı temasa bağlı olarak beyin tarafından oluşturulan anlamlı görüntüler olup, aslında bir yanılsamadır. Kadim zamanlardan günümüze dek renkler, insanoğlunu etkileyen bir unsur olmuş ve her dönemde sanat eserlerinde farklı şekillerde ifade edilmiştir. Şair ve yazarlar da, sanatsal imgeleri somutlaştırmak ya da dile getirilemeyecek düşünce ve duyguları açıklamak için renk sembolizmini kullanmışlardır. Çalışma, alegorik bir eser olan Hüsn ü Aşk’ın renk sembolizmi bakımından incelenmesi ve Galib’in Hüsn ü Aşk’ta renkler yoluyla oluşturduğu imajlar, semboller nelerdir, anlamayı amaçlamaktadır. Bir iddia üzerine yazılan Hüsn ü Aşk, zamansız sanatın ayırt edici özelliklerinden sayılan üslup derinliği ve güçlü bir konu etrafında şekillenmiştir. Türk edebiyatındaki en başarılı temsilcisi Şeyh Gâlib olan Hind üslubu; şiirde incelik ve tuhaf, akıl dışı anlamların icadı, metafizik temalara en ince şekilde değinmek, ayna, kıvılcım, alev, ışıltı, renk adları gibi söz varlığını kullanarak insanlığın ilk hikâye konusu olan aşkı anlatmaktadır.
Кинематограф как источник национальной культуры: Использование этноспорта в кыргызском кинематографе
Authors: Ergeşov Marat , Türk Mehmet Sezai
Published: November 2024

Целью данного исследования является изучение использования видов этноспорта в кыргызском кинематографе, которые сегодня начали возрождаться в тюркском мире. Киноискусство играет важную роль в трансформации культуры, в том числе и видов этноспорта, будущим поколениям. В рамках данного исследования методом целенаправленной выборки было отобрано 18 кыргызских фильмов, содержащих виды этноспорта. Затем, с помощью частотного и категориального методов контент-анализа были определены используемые в фильмах виды этноспорта, а также подсчитано процентное соотношение продолжительности этих сцен к продолжительности фильмов. Кроме того, были определены функции видов этноспорта в киноповествовании, чтобы изучить вклад видов этноспорта в драматургию фильма. Походу анализа кыргызских фильмов выявлено, что 13 видов этноспорта, которые можно сгруппировать как игры с лошадьми, виды стрельбы из лука и разновидности борьбы, а также интеллектуальные игры, использовались в 13 фильмах советского периода и 5 фильмах периода независимости. Результат анализа показал, что уровень использования этноспорта в кыргызском кино очень низок, точнее кроме фильма «Время стойких» нет фильмов, в которых главной темой выступает вид этноспорта. В остальных же фильмах виды этноспорта использованы только в некоторых сценах, либо дополняя сюжет фильма, либо же определяет характер персонажа.