bluuebunny/crossref_metadata_2025 huggingface dataset:
Elucidating the Effects of Methotrexate Therapy on Serum Cytokeratin-18 Levels in Rheumatology
Authors: Balakrishnan Kanimoliyaal , Rajalingham Sakthiswary , Deborah Chew Chia Hsian , Abdul Wahab Asrul , Yaacob Yazmin , Sutan Rosnah
Published: May 2023

Background: CK-18 is a serological marker of apoptosis that has been widely associated with fibrosis and steatosis in NASH. Many studies have showed association CK-18 levels with NAFLD. To date, there is a profound lack of rheumatology studies on the effect of MTX therapy with regard to CK-18 levels. The relationship between CK-18 levels and cumulative MTX dose, MTX treatment duration, weekly MTX dose is not available in the literature.

Objectives: The main purpose of this study was to determine the relationship between serum cytokeratin-18 (CK-18) and cumulative methotrexate dose in rheumatology patients on methotrexate (MTX) therapy. Besides, we studied the correlations between CK-18 and clinical parameters including age, disease duration , duration of MTX therapy, cumulative steroid dose and biochemical parameters such as alanine transaminase (ALT) and aspartate aminotransferase AST).

Methods : We recruited 79 rheumatology patients on methotrexate (MTX) therapy as MTX group and 38 patients not on MTX therapy as non-MTX group . All subjects were tested for their serum CK-18 levels using an enzyme-linked immunosorbent assay (ELISA) test. We identified 20 patients with the highest CK-18 levels and 20 patients with the lowest CK-18 levels and had ultrasound liver performed on them.

Results : The median serum CK-18 levels were marginally higher among the patients on MTX (1.20 ng/mL [0.19-37.15]) compared to the non-MTX group (1.17 ng/mL [0.37-34.32]). There was a significantly positive relationship between serum CK-18 levels and cumulative MTX dose (r = 0.329, p = 0.003) and total duration of MTX therapy (r = 0.284, p = 0.011). Apart from the above-mentioned variables, the CK-18 levels in MTX group significantly correlated with age (r = 0.265, p = 0.018), ALT (r = 0.440, p = <0.001) and AST (r = 0.478, p= 0.004). Ultrasound liver findings showed median CK-18 levels was higher among patients with abnormal liver findings although statistical significance was not reached.

Conclusion : Among patients on MTX therapy, serum CK-18 levels correlated positively with cumulative MTX dose , total duration of MTX treatment , ALT and AST levels. These findings are preliminary and requires validation by future studies in the field of rheumatology.
Potential Immunotherapy of Dendritic Cell-Cytokine-Induced Killer Cells for Refractory Metastatic Colorectal Cancer: A Preliminary Experience of Single Tertiary Hospital
Authors: Ke Tao-Wei , Huang Cheng-Wei , Chang Sheng-Chi , Huang Wen-Liang , Hsu Chin-Ting , Tsai Cheng-Kang , Chen Chien-Lin , Lin Cheng-Li , Yip Hei-Tung , Cho Der-Yang , Tsai Chang-Hai , Chen William Tzu-Liang , Shyu Woei-Cherng , Jeng Long-Bin
Published: May 2023

Background Successful treatment for patients with metastatic colorectal cancer who failed to response to first-line treatment has been a challenge due to their low response rate for later-line treatment and poor progression free survival and overall survival. The application of dendritic cell-cytokine-induced killer cells (DC-CIK) immunotherapy combined with conventional treat-ment, either surgical resection or chemotherapy, showed improvement in survivals in first-line treatment for metastatic colorectal cancer. In this retrospective study, we aimed to evaluate the benefit of dendritic cell-cytokine-induced killer cells (DC-CIK) immunotherapy for patient with refractory metastatic colorectal cancer. Methods A total of 20 patients with refractory metastatic colorectal cancer receiving cell-cytokine-induced killer cells (DC-CIK) immunotherapy were enrolled to this study. Among these patients, 11 patients responded to the treatment and the remaining 9 patients did not. All patients were followed for at least one years and the determination of treatment response was mainly based on image study at 6 months after the completion of treatment. Data were analyzed with Kaplan-Meier method and log-rank test. Results The treatment response rate of the study group is 55% (11/20). The median progression free sur-vival (PFS) and median overall survival (OS) of responsive patients was 7 months and 12 months, respectively. The median overall survival of irresponsive patients was 9.5 months. Four responsive patients received subsequent metastectomy or cytoreduction plus hyperthermic in-traperitoneal chemotherapy surgery (CRS + HIPEC). Conclusion DC-CIK cell-based immunotherapy may provide benefits for patients with refractory mCRC with improved response rate and progression free survival.
Implementing a Prototype Autonomous Fire Detecting and Firefighting Robot
Authors: Azeta Joseph , Ayoade Idowu , Nwakanma Cosmas , Akande Timileyin
Published: May 2023

Fires pose a significant threat to human life and property. An autonomous fire detection and fighting robot has the potential to mitigate the challenges associated with firefighting. This paper presents the implementation of an autonomous fire detection and fighting robot equipped with sensors, algorithms, and actuators to detect, locate, and suppress fires autonomously. The robot's mechanical and electrical components were designed, prototyped, and tested in a controlled environment to evaluate its ability to navigate through obstacles, detect fires, and suppress them autonomously. The results show that the robot effectively detects and suppresses fires, making it a promising solution for firefighting applications. The study contributes to the development of autonomous robots for firefighting, enhancing the safety of firefighters and the effectiveness of firefighting operations.
Physiochemical Properties and Oxidation Status of Pork from Three Rearing System (Organic, Conventional and Traditional)
Authors: Abdullah Fouad Ali Abdullah , Trnková Michaela , Dordevic Dani
Published: May 2023

The aim of the study was to evaluate the impact of different rearing systems (organic, conventional and traditional) on the physicochemical properties and oxidation states of pork meat. Samples (M.biceps femoris) were obtained from producers directly 3 days after slaughtering. Chemical composition (dry matter, protein, collagen, fat, ash), colour (L*, a*, b*) and oxidation state (Thiobarbituric acid reactive substances -TBARS, free fatty acid -FFA and antioxidant capacity-2,2-diphenyl-1-picrylhydrazyl) of the meat samples were determined. The results indicated that the rearing system affects most of the evaluated parameters. The significant difference (P < 0.05) was observed in colour parameter L* and b*, where the conventional pork was darker and the organic pork yellower. Total protein content in meat of conventional pigs was higher, whereas the fat content in the meat of organically reared pigs was higher than the meat of pigs from both other rearing systems. Organic pork was more susceptible to oxidation process due to its higher TBARS and FFA values and lower antioxidant capacity, which may result in inferior technological properties of meat.
Inorganic Chemistry at the Crossroads of Catalysis and Materials Science
Authors: Jain Vimal Kumar , Kedarnath G.
Published: May 2023

Inorganic chemistry has contributed to the progress of human civilization in several different ways. Its activities at the interface with other scientific disciplines has led to emergence of several new fields like organometallic chemistry, bio-inorganic chemistry, solid-state chemistry, environmental chemistry, etc. In the past few decades, it has made inroads in yet another dimension of immense relevance, i.e. nano-science and –technology. In this assay an attempt has been made to present an overview of utility of inorganic and organometallic compounds as precursors for the synthesis of nano-materials with reference to catalysis and materials science. Applications of metal nanoparticles (NPs) and metal chalcogenide NPs, generated through molecular precursor route, in catalysis have been discussed. Synthesis of ternary and quaternary metal chalcogenide nano-materials by molecular precursor route has been reviewed.
Influence of Metal Magnesium Addition on Detonation Initiation in Shock Wave Focusing
Authors: Hu Yu-Peng , Zhang Yun-Tian , Du Peng , Xue Rui , Wang Yi-Jun , Zhou Ben-Quan
Published: May 2023

The process of shock wave focusing can make the strength of shock waves be continuously accumulated and turned into detonation wave in Pulse Detonation Engine (PDE). However, its effective application needs the inlet jets be in high temperature and velocity, which is difficult to be satisfied under certain conditions. Therefore, in this paper, metal magnesium assisted detonation initiation is proposed and the effect of magnesium particle addition on the shock wave focusing process in a kerosene-fueled PDE with cavity configuration is investigated through numerical simulation. The result showed that when the temperature of the premixed fuel/air jets injected in opposite direction was set as 650 K, the collision of leading shock waves on the central axis was the main source of energy deposition and the shock wave focusing could make the detonation be initiated in the cavity. When the temperature of jets is reduced to 550 K, fuel ignition and detonation could not be achieved through shock wave focusing. Then adding metal magnesium particles into the combustor made the energy deposition be enhanced and the detonation be induced. The diffusion of metal particles can significantly change the structure, motion, merging and dissipation of vortices in the flow field. Generally, the shock wave focusing process is basically not affected with metal particles injection. Therefore, this method can be successfully employed for detonation initiation in the cavity when the fuel/air premixed jet temperature is not high for PDE.
Freeze-Drying Process for the Fabrication of Collagen-Based Sponges as Medical Devices in Biomedical Engineering
Authors: Katrilaka Chrysoula , Karipidou Niki , Petrou Nestor , Manglaris Chris , Katrilakas George , Tzavellas Anastasios Nektarios , Pitou Maria , Tsiridis Eleftherios E. , Choli-Papadopoulou Theodora , Aggeli Amalia
Published: May 2023

Freeze-drying is a well-established process in biomedical engineering for the fabrication of three-dimensional open-porous medical devices, especially those based on biopolymers. One of the most used biopolymers in this field is collagen, the most abundant protein in the human body and the main component of the extracellular-matrix, as well as its derivatives. Freeze-dried collagen-based sponges with a wide variety of attributes can be produced by design and have led to a wide range of successful commercial medical devices, foremost for dental, orthopedic, hemostatic and neuronal applications. However, this is still considered a high-cost and time-consuming process that is often used in a non-optimized manner. By combining advances in other technological fields, the opportunity arises to further evolve this process in a sustainable manner, and optimize the resulting products as well as create new opportunities in this field.
Metagenomic Insights Reveal the Microbial Diversity and Associated Algal Polysaccharide-Degrading Enzymes on the Surface of Red Algae among Remote Regions
Authors: Gu Xiaoqian , Cao Zhe , Zhao Luying , Seswita-Zilda Dewi , Zhang Qian , Fu Liping , Li Jiang
Published: May 2023

Macroalgae and macroalgae-associated bacteria together constitute the most efficient metabolic cycling system in the ocean. Their interactions, especially the responses of macroalgae-associated bacteria communities to algae in different geographical locations, is mostly unknown. In this study, metagenomics was used to analyze the microbial diversity and associated algal polysaccharide-degrading enzymes on the surface of red algae among three remote regions. There were significant differences in the macroalgae-associated bacteria community composition and diversity among the different regions. At the phylum level, Proteobacteria, Bacteroidetes, and Actinobacteria had a significantly high relative abundance among the regions. From the perspective of species diversity, samples from China had the highest macroalgae-associated bacteria diversity, followed by those from Antarctica and Indonesia. In addition, in the functional prediction of the bacterial community, genes associated with amino acid metabolism, carbohydrate metabolism, energy metabolism, metabolism of cofactors and vitamins, and membrane transport had a high relative abundance. Canonical correspondence analysis and redundancy analysis of environmental factors showed that, without considering algae species and composition, pH and temperature were the main environmental factors affecting bacterial community structure. Furthermore, there were significant differences in algal polysaccharide-degrading enzymes among the regions. Samples from China and Antarctica had high abundances of algal polysaccharide-degrading enzymes, while those from Indonesia had extremely low abundances. The environmental differences between these three regions may impose a strong geographic differentiation regarding the biodiversity of algal microbiomes and their expressed enzyme genes. This work expands our knowledge of algal microbial ecology, and contributes to an in-depth study of their metabolic characteristics, ecological functions, and applications.
Technical Feasibility of Multimodal Imaging in Neonatal Hypoxic Ischemic Encephalopathy from Ovine Model to Human Case Series
Authors: Hagan Brian , Mujumdar Radhika , Sahoo Jagdish P. , Das Abhijit , Dutta Anirban
Published: May 2023

Hypoxic-ischemic encephalopathy (HIE) secondary to perinatal asphyxia occurs when the brain does not receive enough oxygen and blood. A surrogate marker for ‘intact survival’ is necessary for the successful management of HIE. The severity of HIE can be classified based on clinical presentation, including presence of seizures, using a clinical classification scale called Sarnat staging; however, Sarnat staging is subjective and the score changes over time. Furthermore, seizures are difficult to detect clinically and are associated with a poor prognosis. Therefore, a tool for continuous monitoring on the cot side is necessary, for example, electroencephalogram (EEG) that non-invasively measures the electrical activity of the brain from the scalp. Then, multimodal brain imaging, when combined with functional near-infrared spectroscopy (fNIRS), can capture the neurovascular coupling (NVC) status. In this study, we first tested the feasibility of a low-cost EEG-fNIRS imaging system to differentiate between normal, hypoxic, and ictal states in a perinatal ovine hypoxia model. Here, the objective was to evaluate a portable cot side device and autoregressive (ARX) modelling to capture the perinatal ovine brain states during a simulated HIE injury. So, ARX parameters were tested with a linear classifier using a single differential channel EEG, with varying states of tissue oxygenation detected using fNIRS, to label simulated HIE states in a perinatal ovine hypoxia model. Then, we showed the technical feasibility of the low-cost EEG-fNIRS device and ARX modeling with support vector machine classification for a human HIE case series with and without sepsis. The classifier trained with the ovine hypoxia data labelled ten severe HIE human cases (with and without sepsis) as “hypoxia” group and the four moderate HIE human cases as the “control” group. Furthermore, we showed the feasibility of experimental modal analysis (EMA) based on the ARX model to investigate the NVC dynamics using EEG-fNIRS joint-imaging data that differentiated six severe HIE human cases without sepsis from four severe HIE human cases with sepsis. In conclusion, our study showed the technical feasibility of EEG-fNIRS imaging, ARX modeling of NVC for HIE classification, and EMA that may provide a biomarker to detect sepsis effects on the NVC in HIE.
Filter for Submodular Partition Function: Connection to Loose Tangle
Authors: Fujita Takaaki
Published: May 2023

Loose Tangle is a concept in graph theory that has a dual relationship with branch-width which is well-known graph width parameter. Ultrafilter, a fundamental notion in mathematics, is similarly known to have a dual relationship with branch-width when extended to a connectivity system (X, f). In this compact paper, we revisit and contemplate the interplay between Loose Tangle and Filter through the lens of a submodular partition function.
A Design of Tree Micro Drill Instrument to Improve the Accuracy of Wood Density Measurement
Authors: Yao Jianfeng , Wu Zhenyang , Zheng Yili , Rao Benqiang , Li Zhuofan , Hu Yunchao , Nie Bolin
Published: May 2023

To improve the measurement accuracy of wood density and study the linear correlation between the drill feed resistance and wood density, a new micro drill instrument that can can simultaneously measure the rotation resistance and feed resistance of the drill needle was designed. The test wood samples included hardwood, softwood and conifer. The absolute dry density of each wood sample was measured. The drill resistance data was tested by using self-developed micro drill instrument and Resistogaph 650-SC. 4 linear models between drill resistance and the absolute dry density of wood . The results showed that: the statistical indicators of each model of the self-made micro drill resistance in-strument were better than the corresponding indicators of Resistogaph 650-SC; the coefficient of determination of the linear regression model between the feed resistance of the self-made micro drill resistance instrument and the absolute dry density of wood was 0.946; the statistical indicators of model including rotation resistance and feed resistance, were better than those of the model only including rotation resistance. Therefor, the design proposed in the article is reasonable, and increasing the feed resistance can improve the measurement accuracy of the micro drill resistance instrument for measuring wood density.
Innovation Ecosystem in Hydrocarbon-Based Economies: Opportunities and Challenges
Authors: Al-Sulaiti Ahmed , Madhoun Iman T. , Abdella Galal M. , Hamouda Abdel Magid , Al-Yafei Hussein
Published: May 2023

Innovation is rapidly growing and affecting various industries, including hydrocarbon processing. This study aims to conduct a comprehensive and organized review of the literature on innovation ecosystems and their performance. It will examine existing definitions of innovation ecosystems and related concepts and identify metrics and indicators for measuring innovation and entrepreneurial ecosystems. The term "innovation ecosystem" has gained considerable attention from scholars and practitioners over the past fifteen years. Despite the proliferation of research in this area, there are concerns about its fragmented knowledge base. While previous reviews have highlighted the theoretical connections between innovation ecosystems and related concepts, there is still a need for a more comprehensive understanding of the current state of innovation ecosystem research. The study used a systematic literature review approach that combines bibliographic coupling and content analysis methods, drawing on over 100 studies to identify five streams of current innovation ecosystem research: technology innovation, platform innovation ecosystems, regional development, innovation ecosystem conceptualization and theorization, and entrepreneurship and innovation. The study's contribution lies in decoding the intellectual structure of current innovation ecosystem research and providing targeted recommendations for future research.
Impact of Obesity and Bariatric Surgery on Metabolic Enzymes and P-glycoprotein Activity using Geneva Cocktail Approach
Authors: Ghasim Hengameh , Rouini Mohammadreza , Safari Saeed , Larti Farnoosh , Khoshayand Mohammadreza , Gholami Kheirollah , Neyshaburinezhad Navid , Gloor Yvonne , Daali Youssef , H. Ardakani Yalda
Published: May 2023

The inter-individual variability of CYP450s enzyme activity may be reduced by comparing the effects of bariatric surgery on CYP-mediated drug elimination in comparable patients before and after surgery. The current research will use a low-dose phenotyping cocktail to simultaneously evaluate the activities of six CYP isoforms and P-gp.The results showed that following weight reduction after surgery, the activity of all enzymes increased compared to the obese period, which was statistically significant in the case of CYP3A, CYP2B6, CYP2C9, and CYP1A2. Furthermore, the activity of P-gp after surgery decreased without reaching a statistical significance (p-value>0.05). Obese individuals had decreased CYP3A and CYP2D6 activity than the control group, albeit only CYP3A was statistically important. In addition, there was a trend to increase activity for CYP1A2, CYP2B6, CYP2C9, and CYP2C19 in obese patients compared to the control group, without reaching statistical insignificance (p-value≥0.05). After six months (at least), all enzymes and the P-gp pump activity were significantly higher than the control group except for CYP2D6.Ultimately, a greater comprehension of phenoconversion can aid in altering the patient's treatment. Further studies are required to confirm the changes in the metabolic ratios of probes after bariatric surgery to demonstrate the findings' clinical application. As a result, the effects of inflammation-induced phenoconversion on medication metabolism may differ greatly across persons and drug CYP pathways. It is essential to apply these results to the clinic to recommend dose adjustments.
Lagrange-Kirchhoff Model for curvature of Circular Silicon Plate, Annular Silicon Plate and Taiko Silicon Plate
Authors: Landi Antonio
Published: May 2023

In this work, the analytical Lagrange-Kirchhoff model for the deformation for a taiko plate silicon is proposed. Under the conditions of validity of the linear theory of thin plates, the model is in agreement with the experimental data.
Complete Bifurcation Analysis of the Vilnius Chaotic Oscillator
Authors: Ipatovs Aleksandrs , Victor Iheanacho Chukwuma , Pikulins Dmitrijs , Tjukovs Sergejs , Litvinenko Anna
Published: May 2023

The paper is dedicated to the numerical and experimental study of nonlinear oscillations exhibited by the Vilnius chaotic generator. The need for practical applicability of the mentioned generator in chaotic communication systems defined the necessity to study the operation of the circuit in a wide parameter range. The bifurcation maps and corresponding one-parameter diagrams, obtained and analysed utilising the Method of Complete Bifurcation Groups, reveal the complex nonlinear dynamics and regions of robust chaotic oscillations. Laboratory experiments allow the verification of the numerical results and identification of the most practically relevant phenomena.
Community Health Risk Awareness and Knowledge of Air Pollution in Annadale, Polokwane Local Municipality, Lim-popo Province, South Africa
Authors: Ngobeni Famola Charles , Kekana Mokoko Percy
Published: May 2023

Exposure to air pollution have detrimental effects on the elderly, women, people with pre-existing medical conditions, people living in poverty and children. The aim of the study was to investigate the extent of community awareness and knowledge on the health risks associated with exposure to air pollution. A cross-sectional study design was used for the study, using self-administered questionnaires. A simple random sampling technique was used to select 376 respondents. Systematic sampling method was applied to select the households. SPSS version 26 was used to analyze data. Of 376 respondents, 221 were males and 154 females. 113 were aged between 23-47years and 353 were aware that if they don’t protect themselves against polluted air, they may get sick, with age and educational status associated with their awareness (p < 0.05). About 361 knew what air pollution is and 188 think the air they breathe in Annadale is moderate. A total number of 278 said they feel sick/uncomfortable when the quality of air is bad. About 293 knew that people are exposed to air pollution by breathing contaminated air and 237 identified sewage smell as the main cause of air pollution. Respondents who identified internet and television as the main source of information were 199 and 177 respectively. Those who were not aware of actions implemented to reduce air pollution were 180. Based on the results of the study, respondents are aware of the dangers of exposure to polluted air, and it is necessary that air pollution risk communication strategies be implemented to empower residents.
Corporate Social Responsibility and Return: Social Impact a Case Study of an Emerging Market Oil Industry in Stock Exchange.
Authors: Lizarzaburu Edmundo , Burneo Kurt , García-Gómez Conrado Diego
Published: May 2023

This paper analyzes the relationship between corporate social responsibility (CSR) and social impact within the oil industry in an emerging market (Peru). Following the emerging literature on the social impact field, and using the case study methodology, the findings show that the expected positive relationship is diverse depending on several factors. Specifically, the results reveal that companies must focus on community and environmental responsibility, together with stakeholders' involvement to achieve social impact. However, when companies are weak in any of the previous factors, then the social impact is only partially accepted or even withdrawn.
Research on Formation Pressure Prediction Method for Ultra-Deep Tight Sandstone Based on Collocated Cokriging
Authors: Qiang Wei , Yaoting Lin , Gang Gao , Zhixian Gui , Zhendong Wu , Jiaqi Liu
Published: May 2023

Comparison with conventional reservoirs, the prediction of pressure in ultra-deep tight sandstone formations is difficult. The prediction of seismic pressure is more challenging than well logging pressure prediction. The main methods for seismic pressure prediction include equivalent depth method, Eaton method, Fillippone formula, and its modified versions. Among them, the Eaton method is widely used and has good effectiveness. However, this method relies on difficult-to-obtain normal compaction trend line, which leads to low prediction accuracy in space. To address this issue, a method combining the Eaton method and Collocated cokriging is proposed. The Eaton formula is used to predict formation pressure at the well, with compressional wave velocity as the covariate for predicting the main variable, formation pressure. By simulating the shear wave velocity based on seismic compressional wave velocity, the influence of various parameters on the prediction results is analyzed, and the accuracy of this method is verified by comparing it with other methods. The proposed method is then applied to predict formation pressure in the ultra-deep formations of the Junggar Basin. The simulation results show that the Collocated cokriging method achieves higher planar accuracy and better matches the experimental expectations in terms of prediction results. The application results also demonstrate the scientific effectiveness of the combined method, which has achieved good results in practical production applications.
The Effect of Process Conditions on Sulfuric Acid Leaching of Manganese Sludge
Authors: Safarian Jafar , Eini Ariel Skaug , Pedersen Markus Antonius  Elinsønn , Haghdani Shokouh
Published: May 2023

Manganese sludge, an industrial waste in the ferroalloy industry, contains various components and holds significant importance for sustainable development through its valorization. This study focuses on characterizing a manganese sludge and investigating its behavior during sulfuric acid leaching. The influence of process conditions, including temperature, acid concentration, liquid to solid ratio, and leaching duration, was examined. The results revealed that Mn, Zn, and K are the main leachable components, and their leaching rates increase with increasing temperature, liquid to solid ratio, and time. However, acid concentration requires optimization. High leaching rates of 90% for Mn, 90% for Zn, and 100% for K were achieved. Moreover, it was found that Pb in the sludge is converted to sulfate during the leaching which yields a sulfate concentrate rich in PbSO4. The leaching process for Mn and Zn species appears to follow a second or -third order reaction, and the calculation of rate constants indicated that Mn leaching kinetics are two to five times higher than those for Zn. Thermodynamic calculations were employed to evaluate the main chemical reactions occurring during leaching.
ALASAN KASASI PENUNTUT UMUM DAN PERTIMBANGAN HAKIM MEMUTUS PERKARA KORUPSI DENGAN ADANYA DISSENTING OPINION (STUDI PUTUSAN MAHKAMAH AGUNG 2107 K/Pid.Sus/2017)
Authors: Septiana Putri Annisa Novira , Yulianti Sri Wahyuningsih
Published: May 2023

ABSTRAKS: Tujuan dari penelitian ini adalah untuk mengetahui pembebasan terdakwa sebagai alasan kasasi penuntut umum dalam perkara korupsi sesuai Pasal 253 ayat (1) KUHAP tentang alasan kasasi dan pertimbangan Hakim memutus perkara berdasar dissenting opinion sesuai dengan Pasal 182 jo Pasal 256 KUHAP. Metode penelitian yang digunakan adalah penelitian normatif dengan menggunakan pendekatan kasus. Sumber bahan hukum meliputi bahan hukum primer dan sekunder. Penulisan hukum ini menjelaskan bahwa pembebasan terdakwa sebagai alasan kasasi oleh penuntut umum telah sesuai dengan Pasal 253 ayat (1) KUHAP. Kedua, pertimbangan Hakim dalam memutus perkara tindak pidana korupsi berdasar dissenting opinion telah sesuai dengan Pasal 182 jo Pasal 256 KUHAP tentang pengambilan suara terbanyak sebagai suatu bentuk penjatuhan pidana kepada Terdakwa.

Kata Kunci: Alasan Kasasi, Pertimbangan Hakim, Dissenting Opinion, Tindak Pidana Korupsi

ABSTRACT: The purpose of this study is to determine the defendant's exemption as the reason for the Public Prosecutor's corruption in accordance with Article 253 paragraph (1) of the Criminal Code Procedure concerning the reason for the appeal and the judgment of the judge severed the case of dissenting opinion pursuant to Article 182 Jo article 256 of Criminal Code Procedure. The method of research used is normative research using a case approach. Sources of legal material include primary and secondary legal materials. The writing of this law clarifies that the defendant's exemption as a reason for the public Prosecutor is in accordance with Article 253 paragraph (1) of the Criminal Code Procedure. Secondly, the judge's consideration in the dissenting of corruption-based criminal proceedings in accordance with Article 182 Jo article 256 Criminal Code Procedure about the most votes as a form of criminal proceedings to the defendant.

Key words: Reason for the appeal, Judge’s Consideration, Dissenting Opinion, Corruption Crimes
TELAAH CLOSED CIRCUIT TELEVISION DALAM KONSEPSI PANOPTICON DAN BEWIJSVOERING PADA E-TILANG
Authors: Azhari Muhammad Yusya , Kristiyadi '
Published: May 2023

ABSTRAK: Penelitian ini bertujuan untuk mengetahui peranan Closed Circuit Television atau CCTV dalam sistem tilang elektronik (E-Tilang). Konsep yang digunakan dalam mengetahui peranan CCTV ini adalah konsep Panopticon, yaitu konsep lembaga pemasyarakatan yang dicetuskan oleh Jeremy Bentham yang kemudian diadopsi oleh Michael Foucault. Parameter pembuktian Bewijsvoering juga digunakan sebagai cara untuk mengetahui apakah CCTV dalam sistem E-Tilang tidak melanggar hak-hak privasi masyarakat dalam berlalu lintas. Karena CCTV berperan sebagai alat perekam elektronik yang dapat merekam kejadian-kejadian disekitar area pemasangannya layaknya lembaga pemasyarakatan dalam konsep Panopticon. Jenis penelitian yang digunakan adalah penelitian hukum bersifat normatif atau doktrinal. Sumber bahan hukum yang digunakan adalah bahan hukum sekunder. Berdasarkan hasil penelitian diketahui dalam proses pengawasan lalu lintas aparat penegak hukum menggunakan alat perekam berupa CCTV. Hasil rekaman tersebut digunakan dalam pembuktian di sidang pengadilan dalam rangka pemberian sanksi terhadap pelanggar lalu lintas.

Kata Kunci: CCTV, Panopticon, Bewijsvoering, Pembuktian, E-Tilang.

ABSTRACT: The purpose of this research is to know the role of Closed Circuit Television or CCTV in electronic ticketing systems (E-Ticketing). The concept used in knowing the role of CCTV is the concept of Panopticon, the concept of correctional institutions that was coined by Jeremy Bentham which was later adopted by Michael Foucault. Bewijsvoering's verification parameters are also used as a way to find out whether CCTV in the E-Ticketing system does not violate people's privacy rights in traffic. Because CCTV acts as an electronic recording device that can record events around the installation area as a correctional facility in the Panopticon concept. This type of research is legal research, normative or doctrinal. Sources of legal materials used are secondary legal materials, collection of legal materials by means of literature study. Based on the research results, it is known that in the process of traffic monitoring the law enforcement apparatus use CCTV recorders. The results of the recording are used in evidence in court proceedings in the context of imposing sanctions on traffic violators.

Keywords: CCTV, Panopticon, Bewijsvoering, Evidence, E-Ticketing.
KETERANGAN AHLI KEDOKTERAN JIWA SEBAGAI ALAT BUKTI DALAM PERKARA PEMBUNUHAN YANG DILAKUKAN OLEH PENGIDAP SKIZOFRENIA PARANOID (Studi Putusan Nomor 2353/PID.B/2018/Pn.Mdn)
Authors: Listiyaningrum Istiqomah
Published: May 2023

ABSTRAK: Penelitian ini bertujuan untuk mengetahui kesesuaian keterangan ahli kedokteran jiwa pada pembuktian penuntut umum terhadap perkara pembunuhan yang dilakukan oleh pengidap skizofrenia paranoid dengan Pasal 184 ayat (1) KUHAP. Jenis Penulisan hukum ini menggunakan jenis penelitian normatif yang bersifat preskriptif dan terapan. Pendekatan penelitian yang digunakan adalah pendekatan studi kasus (case study). Bahan hukum yang digunakan adalah bahan hukum primer dan bahan hukum sekunder. Penulis menggunakan teknik pengumpulan bahan hukum studi kepustakaan (library research). Metode analisis bahan hukum menggunakan metode deduksi silogisme. Kasus yang dikaji pada Putusan Pengadilan Negeri Medan Nomor: 2353/Pid.B/2018/PN.Mdn.  Berdasarkan hasil penelitian dan pembahasan yang telah dilakukan maka dapat disimpulkan bahwa keterangan para ahli kedokteran jiwa yang dihadirkan dalam persidangan dalam pembuktian penuntut umum pada perkara pembunuhan yang terdakwanya pengidap skizofrenia paranoid tersebut adalah sah untuk dijadikan sebagai alat bukti sesuai dengan Pasal 184 ayat (1) KUHAP.

Kata Kunci: Alat Bukti, Keterangan Ahli Kedokteran Jiwa, Skizofrenia Paranoid

ABSTRACT: This research aims to determine the conformity of psychiatrist expert information on the evidence of the public prosecutor in the murder case by people with paranoid schizophrenia with article 184 paragraph (1) of Criminal Procedure Code. . The writing of this Law uses a type of normative research that is prescriptive and applied. The research approach used is a case study approach. The legal material used is the primary legal material and secondary legal material. The author uses the technique of collecting library research legal materials (library research). The method of analyzing legal material uses the syllogistic deduction method. Case reviewed in Medan District Court Decision Number: 2353 / Pid.B / 2018 / PN.Mdn. Based on the results of research and discussion that has been carried out, it can be concluded that the expert information of psychiatrists presented in the court hearing the public prosecutor on the evidence in the murder case of the defendant with paranoid schizophrenia is valid to be used as evidence according to Article 184 paragraph (1) of the Criminal Procedure Code.

Keywords:Evidence, The Expert Information Of Psychiatrists, Paranoid Schizophrenia
PERTIMBANGAN MAHKAMAH AGUNG YANG MENGABULKAN KASASI TERHADAP PUTUSAN BEBAS DALAM PUTUSAN NOMOR 1949 K/PID.SUS/2019 TENTANG PERKARA TINDAK PIDANA PERKOSAAN ANAK
Authors: Pertiwi Suci Hesti Giri
Published: May 2023

ABSTRAK: Penelitian ini bertujuan untuk mengkaji aspek-aspek yang mendasari pertimbangan hakim Mahkamah Agung yang mengabulkan kasasi penuntut umum dan membatalan putusan bebas judex facti dalam perkara tindak pidana perkosaan dan menjatuhkan pidana penjara 11 (sebelas) tahun dan denda sebesar Rp.60.000.000,00 (enam puluh juta rupiah) subsider 3 (tiga) bulan kurungan berdasarkan Pasal 256 KUHAP Jo Pasal 81 ayat (2) dan Pasal 82 Undang-Undang Nomor 35 Tahun 2014 tentang perubahan atas Undang-Undang Nomor 23 Tahun 2002 tentang Perlindungan Anak Jo Pasal 64 ayat (1) KUHP. Penelitian ini merupakan penelitian hukum doktrinal yang bersifat preskriptif. Pendekatan yang digunakan dalam penelitian ini yaitu pendekatan kasus (case approach). Jenis data sumber hukum yang terdiri dari bahan hukum dalam penelitian ini yaitu bahan hukum primer dan bahan hukum sekunder. Teknik pengumpulan bahan hukum pada penelitian ini menggunakan studi kepustakaan atau studi dokumen. Dalam menjatuhkan putusan hakim harus memewujudkan nilai keadilan sesuai dengan pertimbangan yuridis dan non-yuridis. setelah mempertimbangkan berbagai aspek, Mahkamah Agung mengadili sendiri dan membatalkan putusan bebas Pengadilan Negeri Cibinong dimana terdakwa terbukti secara sah dan meyakinkan bersalah melakukan tindak pidana perkosaan terhadap anak dibawah umur.

Kata  Kunci:  Pertimbangan  Hakim,  Kasasi,  Mahkamah  Agung,  Tindak  Pidana Perkosaan Anak

ABSTRACT: This research aims to examine the aspects underlying the consideration of Supreme Court judges who granted the public prosecutor's cassation and the limitation of the judex facti free verdict in the case of rape  and imposed a prison sentence of 11 (eleven) years and a fine of Rp.60,000,000.00 (sixty million rupiah) subsider 3 (three) months of confinement under Article 256 of the Criminal Procedure Code (KUHAP) Jo Article 81 paragraph (2) and Article 82 of Law No. 35 of 2015 Years  2014 on changes to Law No. 23 of 2002 on Child Protection Jo Article 64 paragraph (1) of the Criminal Code (KUHP). This study is a prescriptive doctrinal legal study. The approach used in this study is the caseapproach. The type of legal source data consisting of legal materials in this study is primary legal material and secondary legal material. Legal material collection techniques in this study use literature studies or document studies. In handing down a verdict the judge must realize the value of justice in accordance with juridical and non- juridical considerations. After considering various aspects, the Supreme Court tried itself and overturned the Cibinong District Court's free verdict in which the accused was found legally and convincingly guilty of the crime of rape of a minor.

Keywords: Consideration of Judges, Cassation, Supreme Court, Child Rape Crimes
Problematik Definisi Harta Pailit dalam Kepailitan dan PKPU untuk Mencapai Kepastian Hukum
Authors: Tirayo Adriel Michael , Halim Yoefanca
Published: May 2023

Abstrak: Suatu produk hukum diharapkan dapat mewujudkan 3 tujuan hukum, yaitu Keadilan, Kemanfaatan dan Kepastian Hukum. Definisi harta pailit memang tidak disebutkan secara implisit di dalam Ketentuan Umum UU No. 37 Tahun 2004. Suatu ketentuan yang tidak dijelaskan secara implisit di dalam peraturan perundang-undangan tidak dapat memberikan kepastian dan akan menimbulkan multitafsir bagi beberapa orang. Dalam hal ini, permasalahan yang ingin dijawab adalah terkait penerapan pendefinisian “harta pailit” dalam pelaksanaan Kepailitan dan Penundaan Kewajiban Pembayaran Utang. Metode penelitian yang digunakan adalah yuridis empiris dengan bertolak pada data primer yang diperoleh dari sosialisasi pada bank Mandiri, Jakarta. Kemudian analisis data dilakukan secara kualitatif dan kesimpulan ditarik secara induktif. Hasil penelitian menunjukkan bahwa definisi “harta pailit” dalam praktek memang masih tidak jelas dan timbul tindakan semena-mena dalam hal ini dilakukan oleh kurator dengan memasukkan harta pihak ketiga sebagai “harta pailit”. Oleh karena itu, dibutuhkannya definisi yang jelas di dalam UU No. 37 Tahun 2004 tentang Kepailitan dan PKPU terkait dengan apa saja yang termasuk ke dalam “harta pailit”, melalui perubahan UU No. 37 Tahun 2004 karena sudah tidak sesuai dengan perkembangan zaman dan masyarakat.
Kata kunci: Kepailitan; Kepastian hukum; Penundaan Kewajiban Pembayaran Utang

Abstract: A legal product is expected to realize 3 legal purposes, which is Justice, Expediency and Legal Certainty. The definition of bankrupt assets is not mentioned implicitly in the General Provisions of Law No. 37 of 2004. A provision that is not implicitly explained in the legislation cannot provide certainty and will cause multiple interpretations for some people. In this case, the problem to be answered is related to the application of the definition of "bankrupt assets" in the implementation of Bankruptcy and Suspension of Payments. The research method used is empirical juridical based on primary data obtained from socialization at Mandiri Bank in Jakarta. Then the data has been analized qualitatively and conclusions are drawn inductively. The results showed that the definition of "bankruptcy assets" in practice is still unclear and arbitrary actions arising in this matter were carried out by curators by including third party assets as "bankrupt assets". Therefore, a clear definition is needed in Law No. 37 of 2004 concerning Bankruptcy and PKPU related to what is included in the "bankruptcy assets", through changes to Law No. 37 of 2004 because it was not in accordance with the times and peoples.
Keywords: Bankruptcy; Legal certainty; Debt Payment Obligation Postponement
Kesesuaian Pembuktian Penuntut Umum dalam Tindak Pidana Pembunuhan Berencana dengan Pasal 184 KUHAP. Studi Putusan Nomor : 520/Pid.B/2020/Pn.Mtr
Authors: Septian Yola
Published: May 2023

Abstrak: Penelitian ini bertujuan untuk mengkaji isu hukum mengenai kesesuaian pembuktian penuntut umum dalam perkara pembunuhan berencana berdasarkan ketentuan Pasal 184 KUHAP. Metode penelitian yang digunakan adalah penelitian hukum normatif bersifat preskriptif dan terapan. Sumber bahan hukum yang digunakan adalah bahan hukum primer dan sekunder, dengan cara studi pustaka/dokumen, teknik analisis bahan hukum menggunakan metode silogisme dan interpretasi dengan menggunakan pola berfikir deduktif. Berdasarkan hasil penelitian menunjukkan bahwa pembuktian penuntut umum pengadilan negeri dengan menghadirkan alat bukti berupa keterangan saksi, surat, serta keterangan terdakwa dalam Putusan Pengadilan Negeri Mataram Nomor 520/Pid.B/2020/PN Mtr telah sesuai berdasarkan Pasal 184 KUHAP. Dakwaan yang dijatuhkan dengan pembuktian oleh Penuntut Umum harus memiliki hubungan keterkaitan sehingga mendapatkan keadilan bagi masing-masing pihak.

Kata Kunci: Alat Bukti; Pembuktian; Perkara Tindak Pidana Pembunuhan Berencana.

Abstract: This study aims to examine legal issues regarding the suitability of the public prosecutor's evidence in premeditated murder cases based on the provisions of Article 184 of the Criminal Procedure Code. The research method used is normative legal research which is prescriptive and applied. The sources of legal materials used are primary and secondary legal materials, by means of literature/document studies, legal materials analysis techniques using the syllogism method and interpretation using deductive thinking patterns. Based on the results of the study, it shows that the evidence of the district court public prosecutor by presenting evidence in the form of witness statements, letters, and the defendant's statement in the Mataram District Court Decision Number 520/Pid.B/2020/PN Mtr is in accordance with Article 184 of the Criminal Procedure Code. The indictment handed down with evidence by the Public Prosecutor must have a relationship so that it gets justice for each party.

Keywords: Evidence; Evidence; Cases of Premeditated Murder.
Kesesuaian Pertimbangan Hakim dalam Penjatuhan Pidana Denda terhadap Anak Pada Tindak Pidana Narkotika dengan Pasal 71 Ayat (3) UU SPPA (Studi Putusan Nomor: 3/Pid.Sus-Anak/2019/Pn. Bil.)
Authors: Widyacahayani Shafira Safa
Published: May 2023

Abstrak: Artikel ini memiliki tujuan untuk mengetahui apakah pertimbangan hukum hakim pada Putusan Nomor 3/Pid.Sus-Anak/2019/PN. Bil atas penjatuhan pidana denda sebesar Rp.1.000.000.000,00 (satu milyar rupiah) telah sesuai dengan Pasal 71 Ayat (3) Undang-Undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak atas tindak pidana narkotika oleh Anak mengingat pada Undang-Undang Sistem Peradilan Pidana Anak tidak diatur mengenai pidana denda. Metode yang digunakan dalam penelitian ini adalah metode penelitian hukum normatif yang bersifat preskriptif dan terapan. Pendekatan penelitian yang digunakan dalam penelitian ini adalah pendekatan kasus dengan teknik analisis menggunakan metode silogisme deduktif. Berdasarkan hasil penelitian dan pembahasan pada penelitian ini dapat disimpulkan bahwa pertimbangan hukum hakim dalam menjatuhkan pidana denda sebesar Rp. 1.000.000.000,00 (satu milyar rupiah) tidaklah sesuai dengan Pasal 71 Ayat (3) Undang-Undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak.

Kata Kunci: Pertimbangan Hukum Hakim; Tindak Pidana Narkotika; Undang-Undang Sistem Peradilan Pidana Anak

Abstract: This article aims to determine the conformity of judgment considerations on the verdict number: 3/Pid.Sus-Anak/2019/PN. Bil. in sentencing fines of Rp.1.000.000.000,00 (one billions rupiah) with Article 71 Paragraph of Law Number 11 of 2012 concerning the Criminal Justice System for Children of Narcotics Crime by children considering that the Law on the Juvenile Criminal Justice System does not regulate about fines. This research used normative legal research method that is prescriptive and applied. The case approache used in this research and the technical analysis is syllogism deductive. Based on the research it is concluded that the judgment consideration in sentencing fines of Rp.1.000.000.000,00 (one billions rupiah) has not conformed to Article 71 Paragraph 3 of Law Number 11 of 2012 concerning the Criminal Justice System for Children to Narcotics Crime by Children.

Keywords: Judgment Consideration, Narcotics Crime, Law of The Criminal Justice System for Children.
 