bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring DNA methylation profiles in the pathogenesis of human osteoporosis via whole-genome bisulfite sequencing
Authors: Zhang Yinyin , Zhong Yeling , Li Chunmei , Zhang Yukai , Xiong Shishuo , Li Qihuo , Guo Haiwei , Li Ying
Published: December 2024

Background
Osteoporosis is a prevalent bone metabolic disorder characterized by reduced bone mass, disruption of bone microarchitecture, and increased bone fragility, leading to a heightened risk of fracture. This condition significantly impairs patients' quality of life and increases mortality risk. Emerging evidence suggests that DNA methylation may play a crucial role in regulating the expression of genes related to bone metabolism, thereby influencing the development of osteoporosis. However, the precise relationship between DNA methylation and osteoporosis remains unclear and warrants further investigation.
Results
Our study revealed significant differences in both the quantity and ratio of DNA methylation between individuals with osteoporosis and healthy controls, with differences predominantly occurring in CpG islands. GO/KEGG enrichment analyses highlighted distinct osteoporosis-related gene pathways. Notably, we identified two genes, TF and TGFB1, located on chromosomes 3 and 19, respectively, that are potentially involved in the pathogenesis of osteoporosis and are broadly involved in various diseases and biological processes.
Conclusions
These findings indicate distinct methylation patterns between osteoporosis patients and healthy individuals, with differential methylation levels in genes associated with osteoporosis. This research offers new insights into the epigenetic mechanisms underlying osteoporosis.
Lactarius crocogalum (sp.nov.): A new ectomycorrhizal species of Lactarius subgen. Lactarius from the peat swamp forest of Central Kalimantan, Indonesia
Authors: Hafazallah Khalid , Helbert Helbert , Verrone Valeria , Retnowati Atik , Muzahiq Hizbullah Al , Nugroho Teguh Willy , Swarup Sanjay
Published: December 2024

We discovered a new species of Ectomycorrhizal Lactarius belonging to the Russulaceae family: Lactarius crocogalum. The fruit body and root-tip specimens were collected in the tropical peat swamp forest of Sebangau National Park (Central Kalimantan, Indonesia). The fruit bodies were assessed by microscopic and macroscopic morphology features, as well as molecular screening of two nuclear genes, ITS and LSU, whereas the DNA extracted from the root tips was used to validate the ectomycorrhizal ecology of the fungus and to identify the tree host. The obtained ITS and LSU sequences were blasted against a customized database of available sequences of closely related Lactarius strains. The results validate both the taxonomy novelty and the ecological role of Lactarius crocogalum as ectomycorrhizal symbiont of a fagaceous tree.
Agricultural Waste to Potential High-Performance Fibers: Impact of Dry and Wet Pretreatment on Extraction and Properties of Novel Fibers from Grapevine Shoots.
Authors: Rana Princy , Sethi Sabina
Published: December 2024

This study focuses on Vitis vinifera (grape), one of the world's largest crops and an ancient dietary staple, for the development of novel biodegradable and sustainable fibers. Grapevine shoots, post-pruning, are an abundant agricultural residue with little economic value as they are mainly used as fuel or fertilizer. The prime objective of the study was to evaluate the effects of dry and wet pre-treatment on the extraction and physical properties of novel lignocellulosic fibers derived from both the bark and core of waste grapevine shoots, respectively. It was found that, as compared to the dry pre-treatment, extraction done after wet pre-treatment required lower chemical concentrations as well as time and still enhanced fiber length, fineness, strength, and elongation. Physical characterization showed that compared to traditional fibers including jute, flax, kenaf, hemp, ramie, sisal, and coir, these extracted fibers demonstrated superior elongation, tenacity, and length characteristics while maintaining a moderate and comparable fineness. These distinct features make them appropriate for potential manufacturing of yarn and composite materials. Furthermore, the valorization of this otherwise discarded agricultural waste into marketable goods would reduce greenhouse gas emissions associated with its decomposition.
Synergizing CNNs and Transformers for Accurate Face Age Estimation
Authors: Chami Ahmed Chaouki , Ajgou Riadh , Taleb-Ahmed Abdelmalik
Published: December 2024

Estimating the actual and perceived age of human faces has garnered significant interest for its wide-ranging practical applications. Various intelligent scenarios stand to gain from these computational systems capable of accurately predicting individuals’ ages. Automated age estimation systems are particularly valuable in fields such as medical diagnostics, facial product development, casting for films, assessing the impact of cosmetic procedures, and anti-aging treatments. In the realm where deep networks have demonstrated their supremacy as the fron-trunners among machine learning tools, Our approach integrates Convolutional Neural Networks (CNN) with Transformers. This novel system enhances information extraction by utilizing transformer attention mechanisms, rather than solely depending on features extracted from convolutional neural networks for estimating age. Based on the experiments conducted, the system effectively captures the sequential progression and continuous nature of the aging process. Furthermore, the proposed model surpasses the cutting-edge model by delivering exceptional results, achieving the lowest mean absolute errors of 2.31 for MORPH II, 5.35 for CACD, and 2.91 for AFAD.
Two novel orchids mycorrhizal Tulasnella species and their ability to facilitate symbiotic seed germination
Authors: Ma Xiao-Ya , Mala Buasroi , Tan Lei
Published: December 2024

Many Tulasnella species have been identified as true mycorrhizal fungi, playing key roles in nutrient exchange between hosts and their environments, which is crucial for seed germination and seedling development. This study describes four Tulasnella strains isolated from Dendrobium and Paphiopedilum species collected in Thailand. Based on single-locus ITS and four-gene (ITS + mtLSU + ATP + GS) phylogenetic analyses, we introduced two novel species –Tulasnella thailandica sp. nov. and T. epidendroidearum sp. nov. Additionally, two known taxa - T. deliquescens and T. ellipsoidea were identified. Notably, T. ellipsoidea was first identified from Dendrobium chrysotoxum and reported in Thailand. Both ex vitro and in vitro symbiotic seed germination experiments confirmed that all four strains are true orchid mycobionts and are fully compatible with D. chrysotoxum, as they formed pelotons within orchid protocorms, promoted seed germination, and supported protocorm development to advanced stages. Furthermore, T. epidendroidearum sp. nov. Dch-PK-1 significantly increased the protocorm developmental rate of D. chrysotoxum in ex vitro symbiotic seed germination compared to the uninoculated control. This study marks the first attempt to demonstrate that T. ellipsoidea are true mycorrhizal fungi associated with Dendrobium species. The findings on seed germination and seedling growth suggest that these four strains have potential applications for the ex vitro conservation of Dendrobium species.
Optimization of human chaperone BiP production in yeast Pichia pastoris
Authors: Žitkus Eimantas , Čiplys Evaldas , Žiaunys Mantas , Sakalauskas Andrius , Slibinskas Rimantas
Published: December 2024

Background
Human BiP, also known as GRP78, is a molecular chaperone mainly located in the endoplasmic reticulum (ER). However, a growing amount of data also associates BiP with many different functions in subcellular locations outside the ER. Importantly, several diseases have been BiP-related and therefore it could potentially be used for therapeutic purposes. The aim of this study was to optimize a high cell density fermentation process for production of recombinant human BiP (rhBiP) in yeast Pichia pastoris in mineral medium.
Results
P. pastoris cells successfully synthesized and secreted full length rhBiP protein in complex growth medium. However, secreted rhBiP titer was considerably lower when P. pastoris was cultivated in defined mineral basal salt medium (BSM). During rhBiP synthesis optimization in shake flasks it was found that addition of reducing compounds (DTT or TCEP) to mineral BSM medium is essential for high yield rhBiP production. Furthermore, rhBiP secretion in BSM medium was significantly increased by feeding yeast with an additional carbon source. Addition of 2 mM DTT and 0.5-1.0 % of glucose/glycerol to BSM medium increased rhBiP titer ~ 8 times in the shake flasks.
Glucose/methanol mixture feeding with 2 mM DTT addition before induction was applied in high density P. pastoris fermentation in bioreactor. Oxygen limited fermentation strategy allowed to achieve ~70 mg/L rhBiP titer in BSM medium. For rhBiP protein purification hydrophobic interaction and anion exchange chromatography were used. Approximately 45 mg rhBiP was purified from 1 L growth medium and according to SDS-PAGE ~90 % purity was reached. According to data presented in this study, rhBiP protein derived from P. pastoris is a full-length polypeptide that possesses ATPase activity. In addition, we show that P. pastoris-derived rhBiP effectively inhibited neurodegenerative disease-related amyloid beta 1-42 (Aβ42) peptide and alpha-synuclein (α-Syn) protein aggregation in vitro.
Conclusions
A scalable bioprocess to produce rhBiP in P. pastoris was developed providing high yield of biologically active protein in a chemically defined mineral medium. It opens a source of rhBiP to accelerate further therapeutic applications of this important protein.
Socio-economic impact of crop raiding by wild animals in the fringe villages of protected areas
Authors: Pradhan Subarna Moni
Published: December 2024

Crop raiding is a major form of Human-Wildlife Conflict (HWC) that poses a serious threat to human welfare in the fringe villages of Manas National Park in Assam (India). Most of the people living in the fringe villages of Manas National Park rely on agriculture for their livelihoods. Crop raiding also creates notable challenges for wildlife conservation, as people may retaliate against wildlife when the frequency and severity of crop damage escalate—resulting in the injury or death of the wild animals. To assess the socio-economic impact of crop raiding on the people living in the fringe villages of Manas National Park, data were gathered from eight fringe villages through primary sources, including household questionnaires, focus group discussions, interviews, and field observations, along with secondary sources. This study has also identified the various types of crops damaged by wildlife, quantified the economic losses incurred as a result of crop raiding and examined various mitigation measures for HWC practiced by the communities of the fringe villages
Integrating Gray Wolf Optimization with Deep Learning for Enhancing NAM-to-Speech Conversion
Authors: Mani S Godvin , Kumar T Rajesh
Published: December 2024

The non-audible murmur (NAM) microphone captures articulatory movements without vocal fold vibration, making it useful for patients with vocal fold issues. However, NAM signals suffer from poor quality due to the absence of radiation effects from the lips and the low-pass nature of soft tissue, causing high-frequency loss and incomprehensible signals. To improve NAM signal intelligibility, the proposed approach uses deep population-based metaheuristics, particularly Gray Wolf Optimization (GWO). The system has two stages: the first, NAM signals to susurrant signals (NAM2SUS), converts NAM signals into susurrant (whisper-like) signals, while the second, susurrant signals into discernible discourse (SUS2DIDIS), transforms these into intelligible speech. Compared to methods based on ANN and DNN, this approach offers a 25% improvement. Additionally, the SUS2DIDIS transformation system significantly enhances NAM-to-speech conversion, reducing word error rate by 4.15%, making speech more understandable and speaker-independent.
The modification of NCM cathode material prepared by hydrothermal method under pulsed high magnetic field
Authors: Sun Wenrui , Lin Genwen , Zhang Xueqian , Jin Hongming , Zhu Mingyuan , Li Ying
Published: December 2024

High magnetic field serves as a unique technique for the materials preparation which is more applied in the magnetic materials, but seldom in the electrode materials. In this study, the pulsed high magnetic field was employed during the hydrothermal synthesis of the NCM523 precursor. And the electrochemical performances of NCM523 are researched: at a high cut-off voltage range from 3V to 4.5V and current density set at 1C = 180 mA/g, an initial specific discharge capacity is 190.4 mAh/g which is 12.1 mAh/g increased, and after 200 cycles both specific discharge capacity and capacity retention rate increased by 24.4 mAh/g and 8.5%, respectively, comparing to the sample prepared without magnetic field. The mechanism should be that the high magnetic field applied in the formation and growth of NCM crystal could improve its micro-structure such as layer structural, result in the mitigate Li+/Ni2+ mixed-arrangement phenomenon and increase the Li+ diffusion rate.
Downregulation of B7-H4 suppresses tumor progression of tongue squamous cell carcinoma
Authors: Yang Qiong , Zhou Peipei , Ge Jie , Liu Hualian , Xu Tianshu , Yang Xu
Published: December 2024

Objective
This study aims to explore the correlation between B7 homolog 4 (B7-H4) expression in tongue squamous cell carcinoma (TSCC) tissue and prognosis, investigating its role in TSCC development for potential implications in early diagnosis and treatment decisions.
Methods
Immunohistochemical staining assessed B7-H4 expression in TSCC tumor and adjacent tissues. Chi-square tests analyzed the relationship between B7-H4 expression and clinical pathological features, while Kaplan-Meier analysis evaluated overall survival rates. A Cox model assessed the relationship between clinical features and prognosis. Stable downregulation of B7-H4 in TSCC cell lines was confirmed by RT-PCR and Western blot experiments. Functional impacts were examined through proliferation, migration, invasion, apoptosis, and cell cycle assays.
Results
B7-H4 expression was higher in TSCC tumor tissues, correlating with decreased overall survival rates. Cox regression indicated B7-H4 as an independent risk factor for prognosis in TSCC. Downregulated B7-H4 led to decreased proliferation, migration, and invasion, increased apoptosis, and cell cycle alterations in TSCC cells.
Conclusions
This study highlights B7-H4 as a potential immunotherapy target in TSCC, suggesting its significance in prognostic assessment and as a therapeutic avenue for intervention.
Wax deposition law of Bozi ultra-deep condensate gas reservoir in Tarim basin
Authors: Wang Rujun , Tang Yongliang , Chen Dong , Wei Cong , Zhou Wei , Ren Xingnan , Dai Li
Published: December 2024

Wax deposition in gas wells of condensate reservoir is the main factor affecting the development of condensate reservoir.This paper takes Bozi high wax condensate gas well in Tarim Basin as the research object,uses high temperature and high pressure equipment and laser test to carry out wax deposition test in condensate gas reservoir under high temperature and high pressure,uses Differential Scanning Calorimeter test, chromatographic analysis to separate the characteristics of wax deposition,and uses self-developed thin tube dynamic wax deposition equipment to analyze the effects of different flow rates,gas-oil ratio and particles on wax deposition in high temperature and high pressure condensate gas well,and uses multiphase flow wellbore deposition dynamic model to predict the wax deposition law under different daily output.The results show that the highest wax deposition point of Bozi condensate gas is 33.71℃, and its wax content is also the highest.At -20℃,the wax accumulation of condensate oil is lower than that of condensate oil, and the wax content and density of well 102-2 are the highest. With the increase of flow rate, the wax deposition rate decreases.With the increase of gas-oil ratio,the wax formation rate of condensate gas decreases.The dynamic prediction model of multiphase flow wellbore deposition is used to analyze the wax deposition in the wellbore, and it is concluded that there is no wax deposition in the wellbore when the daily output exceeds 3.4×105m3.The research results provide theoretical data support for wax deposition law in ultra-deep condensate gas reservoirs.
Integrative Analysis of Agro-Morphological Traits and Genetic Diversity in Gladiolus (Gladiolus hybridus L.) Using SRAP Markers
Authors: PR Jadhav , AY Jagtap , AD Gadge , AU Solanke , MC Pagariya , GB Kadam , KV Prasad , PG Kawar
Published: December 2024

Gladiolus (Gladiolus hybridus L.) is a popular ornamental crop, known for its vibrant flowers and extensive diversity in color, size, shape, and blooming characteristics—traits that distinguish its species and genotypes. This study aimed to assess genetic diversity and agro-morphological traits in 30 Gladiolus genotypes, using Sequence-Related Amplified Polymorphism (SRAP) markers and multifactorial analysis (MFA). Eight SRAP primer combinations generated 84% polymorphic loci, with an average of 7.875 alleles per primer pair, indicating substantial genetic variability. Cluster analysis grouped the genotypes into distinct clusters, revealing genetic relationships within the germplasm. Agro-morphological traits such as plant height, spike length, flower diameter, and florets per spike showed significant variation across genotypes. MFA highlighted the contributions of these traits to overall diversity, providing insights into trait patterns and enabling the selection of promising parental lines for breeding. The integrative approach of combining genetic and agro-morphological data in this study advances our understanding of Gladiolus diversity, supporting targeted breeding programs aimed at cultivar improvement, conservation, and the development of superior ornamental genotypes for hybridization efforts.
Entanglement Dynamics of Ground State and í µí²«í µí²¯ Symmetry in Non-Hermitian Systems
Authors: Jiang Linzhi , Miao Weicheng , Ma Wenchao
Published: December 2024

In this manuscript, we explore the properties of a non-Hermitian spin-1/2 XY model subjected to alternating imaginary and transverse magnetic fields. Focusing on a two-spin system, we systematically construct the ground state phase diagram and provide an exact calculation of the ground state entanglement via the Negativity measure. Our findings reveal that, within eigenstates influenced by the anisotropy parameter, real magnetic fields, and imaginary magnetic fields, the anisotropy parameter significantly enhances entanglement, whereas the real magnetic field tends to diminish or even annihilate it. Notably, in the ΡΤ-symmetry broken phase, quantum entanglement demonstrates increased resilience to variations in the real magnetic field with the strengthening of the imaginary magnetic field. For eigenstates governed purely by the imaginary magnetic field, we observe that the two-spin entanglement remains maximal (i.e., value of 1) within the ΡΤ-symmetry region, while it gradually declines in the ΡΤ-symmetry broken region as the parameter η0 decreases. An intriguing observation is that the first derivative of the Negativity shows non-analytic behavior at the critical points, highlighting the role of Negativity as a reliable and effective indicator of phase transitions in this non-Hermitian system.
Topology and control strategy of MMC five-port energy router
Authors: Han Xiaoyu , Yang Jianfeng , Zhou Tao
Published: December 2024

With the rapid development of renewable energy sources and new load technologies, the energy router has emerged as a new type of power conversion and distribution equipment. But most energy routers only support single input and single output structures, limiting their ability to access different types and levels of power supply and loads. This paper introduces a energy router that supports multi-voltage forms and levels to meet the diversified needs of distributed power supply and AC/DC load. Fristly, the topological structure of the energy router is deeply analyzed, and the AC/DC power grid with different voltage levels is design. Secondly, this paper studies the control strategy of each part of the energy router, and optimizes the control algorithm to improve the operation stability and efficiency. Finally, using MATLAB as a platform, paper build a simulation model, analyze and test the control strategy in detail, and verify its feasibility and effectiveness.
The Long-Term Impact of Catastrophic Health Expenditure on Household Livelihoods in China: A Quasi-Experimental Analysis
Authors: Zhuang Yan , Zhou Zhongliang , Deng Qiwei , Liu Guanping , Gong Shaoqing , Shen Chi
Published: December 2024

It is a huge public challenge to improve the livelihoods of households suffering from CHE. However, there is a research gap in exploring how long it takes for households to return to normal livelihoods after suffering from CHE, this study aims to provide empirical evidence for it. Four waves (2011, 2013, 2015, 2018) survey data from a nationally representative longitudinal survey (CHARLS) were used in this study. A total of 14076 household-level observations from four-year balanced panel data were included. We applied TWFE models. We find that the livelihood capital of households suffering from CHE in 2011 was still affected by CHE two years later (2013), four years later (2015), even seven years later (2018) and did not recover to the normal level of their matched groups who did not suffer from CHE. The livelihood capital level of households with CHE decreased by 0.014 units of livelihood capital index (0.9%), 0.015 units of livelihood capital index (1.0%), 0.012 units of livelihood capital index (0.7%) respectively in 2013, 2015 and 2018 compared with 2011. Livelihood capital of households in rural areas, western regions, with householders aged 45–60 and with lowest income are more deeply affected by CHE and it takes them more than 7 years to recover. Governments should keep track of the households suffering from CHE, and focus on the condition of livelihood recovery so that health policymakers can appropriately intervene and extend supportive policies for most vulnerable people to reduce the continuous and delayed shock of CHE on household livelihoods.
The age-specific functional response of Blattisocius mali (Acari: Mesostigmata) preying on the acarid mite Tyrophagus putrescentiae
Authors: Jena Manoj Kumar , Michalska Katarzyna , Studnicki Marcin
Published: December 2024

The characteristics, including the foraging behaviour of an adult predator, are crucial for assessing its impact on prey populations within an ecosystem. Our recent research aimed to explore how the age and sex of the adult predatory soil mite Blattisocius mali Oudemans (Acari: Mesostigmata) impact its predatory behaviour when preying on the mould mite Tyrophagus putrescentiae Schrank (Acari: Acaridae). Male or female B. mali of five ages, 2, 10, 18, 26, and 34-day-old were exposed to seven prey densities ranging between 10 and 160 eggs. We employed logistic regression and Hassell's model to determine the type of functional response and its parameters, respectively. Across all ages, both male and female B. mali exhibited Type III functional responses. The handling time (Th) for 10-day-old adult males was the shortest, i.e., 0.0114 days, indicating their highest efficiency at this age. In contrast, the handling times for 34-day-old and 10-day-old female adults were shorter, i.e., 0.0070 and 0.0072 days, respectively, indicating that female B. mali were more efficient at these ages than others. The predation rate varied with age in females but remained unchanged in males. Overall, both male and female B. mali have the potential to serve as effective biological control agents for T. putrescentiae throughout their lives.
First characterization of somatic proteins of trematodes of the family Paramphistomidae by SDS-PAGE isolated from cattle from the Cajamarca region, Peru
Authors: Fernandez-Mendoza Charito Jennyfer , Tayca-Saldaña Antony , Cueva-Rodríguez Medali , Aliaga-Tambo Fernando , Hobán-Vergara Cristian , Rodríguez-Ulloa Claudia , Alvarez-García Wuesley , Quilcate-Pairazamán Carlos , Cabrera-González Marco
Published: December 2024

Paramphistomosis is a gastrointestinal parasitic disease of worldwide distribution, with higher prevalence in tropical and subtropical regions. Its biological cycle has a chronic phase caused by adult trematodes that adhere to the rumen mucosa and a highly pathogenic phase caused by immature trematodes, which induce acute parasitic gastroenteritis. Studies related to the parasite are very scarce in the region of Cajamarca, Peru, regarding the characterisation of antigenic proteins, considering that this parasitosis is endemic and has emerging characteristics. The study aimed to characterise somatic proteins of adult forms of Paramphistomidae in cattle by electrophoresis (SDS-PAGE). For this purpose, 630 adult parasites were collected from the rumen and reticulum of cattle from the processing centre of Cajamarca, Peru. We were able to characterise 21 protein bands from the somatic extract. The molecular weights of these bands ranged from 15 kDa to 119 kDa. This study may help carry out alternative control programmes such as developing vaccines, choice of appropriate drugs due to the therapeutic failures expressed by this parasite.
WITHDRAWN: Do property rights explain the inverse relationship between grassland size and productivity?
Authors: Zhang Mingxue , Li Dongqing
Published: December 2024

In this study, leveraging household panel data from five major pastoral provinces in China, we illustrate a robust inverse relationship (IR) between grassland size and productivity within pastoral areas. Our investigation reveals that the certification of grassland property rights emerges as a plausible exogenous factor contributing to this unexplained IR. The persistence of the IR among households with clear grassland property rights, contrasted with its absence among those with ambiguous rights, underscores the role of property rights certification. The emergence of grassland misallocation and fragmentation during the property rights certification process appears detrimental to grassland productivity, potentially explaining this phenomenon. Additionally, our analysis of herder adaptive strategies, specifically participation in the grassland rental market and cooperative management, underscores their potential in alleviating the IR. These findings offer vital policy insights crucial for promoting sustainable and efficient utilization of marginal land, particularly in the context of grasslands.
Vom Piratensender zum Bürgerfunk
Authors: Roth Wolf-Dieter
Published: December 2024

Rundfunk war in Deutschland zuerst rein militärisch, dann staatlich, dann öffentlich-rechtlich, dann kommerziell. Doch als ‚Piratensender‘ gab es immer schon auch Stationen, die nicht kommerziell und auch nicht öffentlich-rechtlich waren. Sie stehen dem heutigen ‚Bürgerfunk‘ und den ‚offenen Kanälen‘ inhaltlich am nächsten.
MOOCs – „E-Learning für alle?“
Authors: Merz Redaktion
Published: December 2024

Sogar in ‚offline‘-Medien wurden sie bereits thematisiert: ‚MOOCs‘ (Die Zeit Nr. 24/2013). Übersetzt bedeutet das Kürzel „Massive Open Online Course“ und bezeichnet ein Format offener, (meist) universitärer Online-Lehrveranstaltungen. „Massive“ bezieht sich dabei vorrangig auf die Teilnehmerzahl. Diese kann bei einigen hundert, aber (in xMOOCs, s. u.) auch einigen zehntausend Teilnehmenden liegen. „Open“ meint einerseits die Möglichkeit der voraussetzungslosen Teilnahme – vorrangig, was Kostenfreiheit (des Kurses, nicht immer auch der Zertifizierung) und die Freiheit von institutionellen Bindungen angeht. In cMOOCs (s. u.) kann sich das „open“ weiterhin auf Merkmale des Lehr-Lern-Prozesses selbst, zum Beispiel auf die Lernziele oder die eingesetzten medialen Kommunikationsformen beziehen. „Online“ bedeutet, dass das Lernen im Internet stattfindet – auf bestimmten Kursplattformen oder mit Nutzung verschiedener Social-Media-Anwendungen (z. B. Blogging- oder Microblogging-Dienste). Bei einigen wenigen MOOCs ist aber auch eine Bewegung hin zum ‚Blended Learning‘ zu beobachten – so gab es zum Beispiel beim opco12 („Trends im E-Teaching“) eine Präsenzveranstaltung als Kursabschluss. „Course“ bezeichnet im weitesten Sinne ein zeitliches Arrangement von Themen und Inhalten – es gibt einen vorab definierten Kurszeitraum, zumeist ein inhaltliches „Curriculum“ und eine zeitliche Taktung der Lerneinheiten.
Dies unterscheidet MOOCs von einzelnen Webinaren einerseits und zeitüberdauernd angelegten Informationsangeboten bzw. Communitys andererseits. MOOCs lassen sich je nach Lernarrangement unterscheiden in xMOOCs (x für „extension“) und cMOOCs (c für „connectivism“). xMOOCs ähneln traditionellen Vorlesungen, die ins Netz gestellt, mit Aufgaben und gegebenenfalls einem Diskussionsforum versehen werden und mit einem Test abgeschlossen werden können. cMOOCs setzen neben der Wissensvermittlung über bereitgestellte Materialien und/oder online abrufbare Vorträge vorrangig auf die Vernetzungs- und Reflexionspotenziale der Teilnehmerinnen und Teilnehmer. MOOCs sind eine relativ neue Entwicklung (die ersten MOOCs gab es 2008, zum ‚Trend‘ wurden sie etwa seit 2011), so dass noch viele Fragen bezüglich ihres Stellenwerts für das Thema „E-Learning“, in Hochschuldidaktik und Weiterbildung offen sind: Welche Form eignet sich für welche Zielsetzungen, Inhalte und Zielgruppen? Was ist an den einzelnen Varianten tatsächlich didaktisch „neu“? Können (einzelne) Hochschulen die Entwicklung nutzen, um wirtschaftlichen Erfolg zu haben? Welche sozialen und bildungspolitischen Folgen hat die Entwicklung?
Corona und das Bildungssystem – Belastung und Lichtblick in einem
Authors: Neuleitner Dana
Published: December 2024

Das Jahr 2020 stellte den Alltag auf den Kopf. Lockdowns und die Schließungen von Betreuungs- und Bildungseinrichtungen zeigen die Wichtigkeit der Digitalisierung und funktionierender Strukturen. Das Lehren und Lernen musste und muss auf neue Weise stattfinden. Während das Zusammenbringen von Digitalisierung und Bildung vielerorts Probleme bereitete, wurde gleichzeitig an Lösungen gearbeitet.
Medienpädagogik im Kontext von Mediensuchtprävention
Authors: Lutz Klaus , Wagner Ulrike
Published: December 2024

Die gesellschaftliche Lage ist derzeit gekennzeichnet durch zwei Pole: die Forderung nach freiheitlichem Diskurs und Vielfalt sowie die Vereinfachung und Polemisierung komplexer Fragestellungen und Probleme. Im Artikel wird am Beispiel des Themenkomplexes Mediensuchtprävention der Frage nachgegangen, welche Rolle die Medienpädagogik und die aktive Medienarbeit im Kontext von Prävention spielen (können) und in welche Bedingungen medienpädagogische Arbeit dabei eingebunden ist.
#29 – Sprache in den Medien Teil 2
Authors: Struckmeyer Kati , Materna Georg
Published: December 2024

Vergleichbare Ereignisse können durch mediale Darstellung unterschiedlich bebildert, unterschiedlich beschrieben werden, wodurch verschiedene Bewertungen in die mediale Darstellung miteinfließen können. Das Phänomen nennt sich ‚Framing‘ – und das ist grundsätzlich weder negativ noch positiv zu bewerten. Dr. Georg Materna erklärt im Interview mit Kati Struckmeyer, was ‚Framing‘ genau ist, warum es ganz nützlich ist, aber wann es auch problematisch werden kann. Er ist Ethnologe, Kommunikations-, Medien- und Religionswissenschaftler und arbeitet als wissenschaftlicher Mitarbeiter am JFF – Institut für Medienpädagogik.
Spannende Lektüre:
Kübra Gümüsay: Sprache und Sein
Robert M. Entman: Framing: Toward Clarification of a Fractured Paradigm
Porismita Borah: Comparing Visual Framing in Newspapers: Hurricane Katrina versus Tsunami
RISE – Jugendkulturelle Antworten auf islamistischen Extremismus
Gegenöffentlichkeit in kommerziellen Plattformen und digitalen Infrastrukturen
Authors: Wimmer Jeffrey
Published: December 2024

Wurden Phänomene der Gegenöffentlichkeit früher mit den Begriffen Partizipation und Emanzipation in Verbindung gebracht, stehen Alternativmedien heute häufig prototypisch für identitäre und demokratiefeindliche Kommunikationsprozesse. Der Essay nimmt die aktuelle Gemengelage zum Anlass, die umfassende digitale Transformation sowohl von Meinungsbildung als auch des Menschseins zu skizzieren. Einen besonderen Stellenwert nimmt die Plethora an digitalen Plattformen und deren Logiken und Mechanismen ein. Der Beitrag schließt mit einem Plädoyer für eine stärkere Berücksichtigung dieser Kontexte in der Aktiven Medienarbeit.
#71 – Medienpädagogik und KI Teil 4: Josephine Ballon von HateAid über die Regulierung von KI
Authors: Merz Redaktion , Ballon Josephine
Published: December 2024

HateAid ist eine gemeinnützige Organisation, die Opfern digitaler Gewalt unmittelbar Beratung und rechtliche Unterstützung bietet. Auch politisch ist das Team von HateAid sehr aktiv und setzt sich zum Beispiel dafür ein, dass es nicht mehr so erschreckend einfach ist, pornografisches Bild- und Videomaterial mit KI zu manipulieren bzw. zu erstellen, da die Auswirkungen für die Opfer immens sind. Wir sprechen dazu mit Josephine Ballon, Geschäftsführerin von HateAid.
«ВСЕПРАВОСЛАВНЫЙ ЛИДЕР»: ЛОЗАННСКАЯ КОНФЕРЕНЦИЯ ИРОЛЬ КОНСТАНТИНОПОЛЬСКОГО ПАТРИАРХАТАВ ПРАВОСЛАВНОМ МИРЕ
Authors: А.А. Чибисова , П.В. Ермилов
Published: December 2024

Издревле Константинопольский патриархат имел большое значение для православного мира как один из важнейших церковных центров. Однако к началу 1920-х гг. его существование оказалось под угрозой полного уничтожения из-за потери почти всей своей паствы, покинувшей территорию Турции по итогам греко-турецкой войны. Политические преобразования в Турции поставили под вопрос дальнейшее пребывание патриархата в Стамбуле. Возможным выходом из этой ситуации могло стать доказательство патриархатом своей особой роли в православном мире, которая требовала бы его дальнейшего пребывания в историческом месте. Эта идея удачно совпадала с интересами великих держав, которым не было выгодно удаление патриархата из Константинополя. Заявление Фанаром претензий на всеправославное лидерство стало реакцией на дискуссии о возможности выдворения патриархата с территории Турции, которые велись в рамках Лозаннской мирной конфе-ренции. Именно это обсуждение создало благоприятную почву для развития концепции о Константинопольском патриархате как центре православного мира, которая была использована для давления на турецкое правительство. Немаловажную роль в развитии этой идеи сыграли европейские политики и западная пресса. Данная статья посвящена интерпретации роли Константинопольского патриархата в православном мире странами-участницами Лозаннской конференции в связи с их борьбой за свои политические интересы. Исследование основывается на официальных дипломатических документах и материалах периодической печати.

From ancient times the Patriarchate of Constantinople has played a significant role as one of the most important sees of the Orthodox world. However, by the beginning of the 1920s its existence was under threat of total elimination due to the loss of almost all its flock after the Greco-Turkish war. The ensuing political reforms in Turkey called into question the continued residence of the Patriarchate in Istanbul. A possible way out of this situation for the Patriarchate was to prove its special role in the Orthodox world, a role that demanded its preservation in its historical place. Fortunately, this idea coincided with the interests of the great powers. The Phanar’s claims at Pan-Orthodox leadership came as a reaction to the discussions about the possible expulsion of the Patriarch from Turkey, which were conducted within the framework of the peace conference at Lausanne. It was these discussions that created a favorable background for the conception of the Patriarchate of Constantinople as the center of the Orthodox world. The authors deal in the article with the interpretation of the role of the Patriarch by the participant countries in the Lausanne conference against the background of their struggle for their own political interests. The research is based on official diplomatic documents and periodical press.
ЗАМЫСЕЛ ЕЩЕ НЕ ТОЧКА… СБОРНИК «РУССКАЯ НАУКА» В РЕАЛИЯХ СОЦИАЛЬНОГО ЭКСТРИМА
Authors: В.П. Корзун
Published: December 2024

Размышление над книгой: Судьба проекта «Русская наука» 1916-1920 (К столетию Комиссии по изданию сборника «Русская наука»): Статьи и документы/ Отв. ред. чл.-корреспондент РАН Ю.М. Батурин; ред.-сост. В.М. Орел, Г.И. Смагина. СПб.; М., 2016. 848 с. Опубликованные статьи и документальные публикации позволяют представить один из первых науковедческих проектов в отечественной науке в контекстах развития мирового науковедения, экстремальных условий Первой мировой войны, революционного и постреволюционного периодов, внутринаучных процессов и практик, индивидуальных стратегий ученых.

Reflection on the book: The fate of the project “Russian Science” 1916-1920 (On the centenary of the Commission for the publication of the collection of “Russian Science”): Articles and documents / Otv.red. Corresponding Member of RAS Yu.M. Baturin; Red.-sost. V.M. Orel, G.I. Smagina. St. Petersburg; M., 2016. 848 p. The published articles and documentary publications make it possible to present one of the first science projects in the Russian science in the context of the development of world science, the extreme conditions of the First World War, the revolutionary and post-revolutionary periods, the intra-scientific processes and practices, and the individual strategies of scientists.
«СУЩЕСТВУЕТ ЛИ СОЦИАЛИСТИЧЕСКАЯ АНТИЧНОСТЬ?»к исследованиям рецепции греко-римской античностив странах Центрально-Восточной Европы
Authors: А.В. Ашаева
Published: December 2024

В статье рецензируются коллективная монография Classics and Class. Greek and Latin Classics and Communism at School. Warszawa: Wydawnictwo DiG, 2016 («Классики и класс. Греческие и латинские классики и коммунизм в школе»), а также издание A Handbook to Classical Reception in Eastern and Central Europe. Oxford: Wiley-Blackwell Pub., 2017 (Справочник по рецепции античности в Восточной и Центральной Европе), в которых демонстрируется, что проблема рецепции античности становится не только предметом академического интереса, но и актуальной повесткой обсуждения культурной политики, исторической памяти, исторической и культурной идентичности стран Центрально-Восточноевропейского ареала. Этот интерес, в случае с осмыслением античного наследия, оказывается основанным не столько на географических, сколько на социокультурных границах. Под локацию Центрально-Восточноевропейского региона попадают 13 стран (включая помимо Хорватии, Словении, Чехии, Польши, Венгрии, Румынии, Боснии и Герцеговины, Сербии, Черногории, Болгарии, России также Армению и Грузию). Рецензируемые издания, по сути, подводят окончательную черту под вопросом о существовании еще одной самостоятельной традиции обращения к античному прошлому в контексте культурно-исторической специфики региона.

The article reviews the collective monograph «Classics and Class. Greek and Latin Classics and Communism at School. Warszawa: Wydawnictwo DiG, 2016» and «A Handbook to Classical Reception in Eastern and Central Europe. Oxford: Wiley-Blackwell Pub., 2017», which clearly demonstrates that the problem of the reception of Classics is not only a matter of academic interest, but also an urgent agenda for the discussion of cultural policy, historical memory, historical and cultural identity of the countries of the Central-Eastern European area, which, in the case of the comprehension of the ancient heritage, is based not so much on geographical as on sociocultural boundaries. The region of Central and Eastern Europe consist of 13 countries (including in addition to Croatia, Slovenia, Czech Republic, Poland, Hungary, Romania, Bosnia and Herzegovina, Serbia, Montenegro, Bulgaria, Russia, Armenia and Georgia). Peer-reviewed publications, in fact, bring an end to the question of the existence of another independent tradition in connection to the ancient past in the context of the cultural and historical specificity of the region.
Evaluating the effects of IFRS 9 on Jordanian banks’ credit and financial metrics
Authors: Morshed Amer
Published: December 2024

Adopting International Financial Reporting 9 is critically relevant as it significantly transforms accounting practices, particularly in credit risk management, for banks in Jordan. The primary purpose of this study is to examine the impact of implementing International Financial Reporting 9 on the financial performance and credit risk management practices of Jordanian banks. A quantitative analysis was conducted using the Difference-in-Differences approach and Fixed Effects models on data from 19 banks operating between 2012 and 2022.The results indicate that the adoption of International Financial Reporting 9 led to a substantial increase in loan loss provisions, with a mean increase of 0.25 (t-value = 18.00). This increase in loan loss provisions negatively affected profitability metrics such as Return on Assets and Return on Equity, which showed mean decreases of 0.0857 (t-value = 4.22) post-implementation. Despite the negative impact on profitability, the findings also highlight improvements in financial transparency and stability due to more accurate credit risk assessment.While the adoption of International Financial Reporting 9 imposes operational and financial challenges, it enhances the robustness and clarity of financial reporting in Jordanian banks.
Analyzing YG Entertainment's Financial Impact: Addressing Brand Image Decline and Solutions
Authors: Sarjono Haryadi , Zetta Azlia , Sitorus Grace Cynthia Magdalena , Soeratin Boyke Setiawan
Published: December 2024

This research explores the impact of YG Entertainment's strategy in 2019 on the company's financial condition and image after a series of problems involving its artists in 2019. YG Entertainment, a prestigious South Korean entertainment company, faced major challenges, including prostitution-related controversies, drug scandals, and tax problems. These problems caused a decline in the value of the company's shares and raised concerns among investors and fans. This research aims to investigate the strategies implemented by YG Entertainment to recover from financial losses and assess the effect of these solutions on the company's financial condition. In addition, this research aims to measure the magnitude of losses experienced by YG Entertainment and the extent of financial recovery after implementing the strategy. Next, this research explores the importance of brand image in influencing the financial condition of entertainment companies. The research findings serve as a source of knowledge for readers who want to understand real cases of how companies overcome crises and their sequential impacts. For the author, this research contributes to knowledge and learning in exploring the dynamics of the entertainment industry which is full of challenges. Further research explored the problems faced by YG Entertainment in 2019, with scandals involving prominent artists. The impact of this problems on the company's share value and market capitalization is discussed, showing the seriousness of the challenges faced by the entertainment giant. YG Entertainment's solution involves the debut of a new boy band, re-planning the presence of artists who have been absent for a long time, and renewing contracts. Research shows that this strategy produces a positive response.Overall, this research provides valuable insight into the dynamic relationship between brand image, financial condition, and crisis management in the entertainment industry, using YG Entertainment as a case study.
The Effect of Experiential Brand Activation Through Vidio's "Roaring Night" Event on Customer Trust
Authors: Dianita Indria Angga , Faaiz Muhammad Al , Gracia Amanda Bunga , Seprina Wa Ode
Published: December 2024

The growth of Over-The-Top (OTT) services has led to a cultural shift towards streaming, which has been accompanied by a rise in content piracy. As the official broadcaster for the English Premier League in Indonesia, Vidio encounters significant challenges from piracy that undermine customer trust and loyalty. Declines in customer trust can lead to increased customer attrition and reduced loyalty. To address these issues and rebuild customer trust, Vidio implemented an Experiential Brand Activation strategy through the "Roaring Night" event. This study investigates how Experiential Brand Activation affects customer trust using a quantitative research method, surveying 400 members from 11 English Premier League fan communities in Jakarta. The findings show a positive link between Experiential Brand Activation and customer trust. However, the correlation analysis reveals a weak but statistically significant relationship (coefficient 0.180, p = 0.000), with Experiential Brand Activation accounting for only 3.2% of the variance in customer trust. This indicates that other factors also play a role. Future research should use qualitative methods to explore these additional factors, including customer engagement, celebrity endorsements, and loyalty. This study provides valuable insights for OTT marketing strategies, highlighting the importance of a holistic approach to enhancing long-term consumer trust and loyalty.

Studi ini memberikan wawasan berharga untuk strategi pemasaran OTT, menyoroti pentingnya pendekatan holistik untuk meningkatkan kepercayaan dan loyalitas konsumen jangka panjang.
Machine Learning-Based Malicious Website Detection Using Logistic Regression Algorithm
Authors: Pastika Puan Bening , Alamsyah Alamsyah
Published: December 2024

Cybercrime is an increasing threat that occurs while exploring the internet. Cybercrime is committed by cybercriminals who exploit the web's vulnerability by inserting malicious software to access systems that belong to web service users. It is detrimental to users, therefore detecting malicious websites is necessary to minimize cybercrime. This research aims to improve the effectiveness of detecting malicious websites by applying the Logistic Regression algorithm. The selection of Logistic Regression is based on its ability to perform binary classification, which is important for distinguishing between benign and potentially malicious websites. This research emphasizes a preprocessing stage that has been deeply optimized. Data cleaning, dataset balancing, and feature mapping are enhanced to improve detection accuracy. Hybrid sampling addresses data imbalance, ensuring the model is trained with representative data from both classes. Experimental results show that the Logistic Regression implementation achieves an excellent level of accuracy. The developed model recorded an accuracy of 92.60% without cross-validation, which increased to 92.71% with 5-fold cross-validation. The novelty of this research lies in the significant increase in accuracy compared to previous methods, demonstrating the potential to improve protection against malicious website threats in an increasingly complex and risky digital environment. This research makes an important contribution to the development of digital security detection technologies to address the ever-growing challenges of cybercrime.