bluuebunny/crossref_metadata_2025 huggingface dataset:
TECHNOLOGIES OF VIRTUAL AND AUGMENTED REALITY IN THE EXCURSION BUSINESS
Authors:   Chernivtsi Institute Trade and Economics of SUTE, Chernivtsi, Оlha Кhytrova , Halyna Dolha
Published: July 2023

The tourism business, during the crisis, is faced with a number of challenges caused by a decrease in tourist activity at both the national and international levels. Therefore, it becomes important to search for new alternative technological solutions to provide interactive tourist information applications, tours or to provide users with opportunities to create interesting content. The very essence of augmented reality is more than just a novelty or a new frontier in applications. It will be one of the driving forces behind innovation in sales and marketing over the next decade. By using AR, promising companies will be able to improve the product they offer to their customers, which will lead to increased business opportunities and sales. The main features of using augmented reality tools are the correct development of the software from the point of view of design and presentation. Also an important element is the combination of augmented and virtual reality, placement of special signs, codes and images for interaction, or adapted applications for mobile and stationary devices. Also, at this stage of the development of these technologies, in some areas, sufficiently large investments may be needed to introduce augmented reality into the production and sales process. In the conditions of the current growth of global competition, this issue becomes very important, in order to be able to compete in the markets and to have the opportunity to attract and interest the majority of the audience and bring a new one. The general result of this research is obtaining this information, and delivering it to the audience and reviewing this material among specialists.
DIGITALIZATION OF TOURISM ENTERPRISES IN CRISIS
Authors:   State University of Trade and Economics, Kyiv, Hanna Mykhailichenko , Valeriia Lysiana ,   State University of Trade and Economics, Kyiv
Published: July 2023

The article is devoted to the study of digitalization of tourism business and its definition. Based on the studied data, a definition of digitization is proposed. The state of the tourism industry and the innovative component of economy at the current stage is analyzed. The main principles of digitization are highlighted, examples of digital transformations of different levels at tourism enterprises are considered: work with clients, operational business processes and the general business model (management). The following general philosophical, general scientific and specialized methods were used: analysis and synthesis, descriptive method, and statistical and graphic method of data presentation. Using the method of description, we have indicated the results of the scientists’ research on this topic. The analysis and synthesis of the main principles of digitalization processes of tourism enterprises are highlighted and determined. Statistical and graphic presentation methods are used in the analysis of trends in the impact of crisis phenomena on tourism in general and the presentation of research data in a form optimized for perception. The author analyzed the current condition to implement the innovative element of tourism business enterprises, defined the concept of "digitalization" and indicated the main principles of its implementation. The developed step-by-step system and the proposed principles of digitalization can be used by stakeholders in the process of analyzing the readiness of enterprises for digitalization. Further scientific research is planned as a study of the business processes of tourism enterprises, providing recommendations in the field of strategic management based on digitalization tools.
MODERN MARKETING TOOLS FOR THE PROMOTION OF GOODS AND SERVICES
Authors:   Chernivtsi Institute Trade and Economics of SUTE, Chernivtsi, Iryna Losheniuk , Oksana Zeleniuk ,   Chernivtsi Institute Trade and Economics of SUTE, Chernivtsi
Published: July 2023

The enterprise's marketing activity on the market is aimed at ensuring its economic efficiency, competitiveness and financial stability. Total quarantine restrictions and the russian-Ukrainian war introduced drastic changes in the organization of marketing activities. Traditional marketing tools are being transformed into digital ones. Therefore, the problem of studying modern marketing tools, which are gaining popularity under the influence of active processes of digitalization, is gaining special relevance. The purpose of the study is to consider and specify modern marketing tools for promoting the company's products on the market, adapted to the digital environment. In the process of carrying out the research, general scientific methods were used: analysis, systematization, generalization, graphic presentation. It was found that the transfer of all spheres of life to the digital plane necessitates the use of new approaches to marketing activities adapted to the digital environment. The main goals of Internet users, determined by specialists of the Oberlo portal, were analyzed. It was found that in 2023, 43.1% of users will use the Internet to buy goods and services, which is 15.6% more than in 2020. It has been established that, in modern conditions, the leading positions in the promotion of the company's goods on the market belong to modern marketing tools: social media marketing, advertising in social networks, content marketing, video marketing, targeted advertising and retargeting. Each of these tools helps companies reach their target audience in ways that resonate and build a sense of trust between brand and customer. It has been established that it is advisable for enterprises to actively use video marketing, content marketing or retargeting to advertise goods in social networks; in order to reduce the cost of marketing activities - video marketing and targeted advertising. The tools of social media marketing considered in the course of the study can be used by domestic enterprises in order to obtain the maximum beneficial effect in the form of an increase in the level of sales and improvement of awareness about the company, taking into account the current limitation in financial resources. We see prospects for further research in determining the prospects for using retargeting in Ukraine, clarifying its differences from targeting.
Kidney and Cancer Outcomes with Standard Versus Alternative Chemotherapy Regimens for First-Line Treatment of Metastatic Urothelial Carcinoma
Authors: Côté Gabrielle , Alqaisi Husam , Chan Christopher T , Jiang Di Maria , Kandel Christopher , Pelletier Karyne , Wald Ron , Sridhar Srikala S. , Kitchlu Abhijat
Published: July 2023

Key Points

Many patients with metastatic urothelial carcinoma are deemed cisplatin-ineligible because of reduced kidney function. Options include split-dose cisplatin or carboplatin.

There was no significant association between regimen type and AKI. Alternative regimens were associated with higher risk of progressive disease.

There is a need to revisit cisplatin eligibility criteria and develop strategies to optimize cancer treatment for patients with CKD.

Background

Cisplatin-based chemotherapy regimens remain the optimal first-line treatment for patients with metastatic urothelial carcinoma (mUC). However, many patients are deemed cisplatin-ineligible, predominantly because of reduced kidney function. Other treatment options include split-dose cisplatin, carboplatin, and non–platinum-based regimens. We compared the incidence of AKI and cancer outcomes within three chemotherapy regimens.

Methods

We conducted a single-center retrospective study of patients with mUC who received first-line chemotherapy from 2005 to 2019. We compared standard gemcitabine–cisplatin (gem-cis) with two alternative regimens: (1) gem-cis split-dose regimen (split) with cisplatin divided over days 1 and 8 and (2) combination of gemcitabine–carboplatin or single-agent gemcitabine (gem/gem-carbo). The primary outcome was Kidney Disease Improving Global Outcomes–defined AKI. Secondary outcomes included overall survival and progression-free survival.

Results

We identified 183 patients (98 gem-cis, 32 split, and 53 gem/gem-carbo). Median baseline eGFR in the gem/cis group was 78 ml/min per 1.73 m2 (interquartile range, 66–91), in the split group 64 (48–77), and in the gem/gem-carbo 45 (33–57). There was no significant association between regimen type and incidence of AKI when adjusted for age, Eastern Cooperative Oncology Group, baseline eGFR, hypertension, diabetes, and visceral disease. The adjusted hazard ratios were 1.31 (95% confidence interval [CI], 0.61 to 2.78; P = 0.49) and 0.98 (95% CI, 0.46 to 2.07; P = 0.95) for split and gem/gem-carbo groups, respectively, versus gem-cis. Split and gem/gem-carbo regimens were associated with higher mortality and progressive disease relative to gem-cis with an adjusted hazard ratio of 1.54 (95% CI, 1.02 to 2.33; P = 0.04) and 1.96 (95% CI, 1.31 to 2.95; P < 0.01), respectively. Median progression free survival was 8.1 (interquartile range, 4.6–14.8), 6.1 (4.1–9.3), and 4.4 (2.3–8.6) months in the gem-cis, split, and gem/gem-carbo groups.

Conclusions

There was no significant difference in the incidence of AKI between the three regimens studied. However, standard gem-cis was associated with improved cancer outcomes. Novel regimens and kidney protective strategies are needed for patients with mUC with kidney disease.
Analisis Pengaruh Jumlah Variasi Katalis MeOH Pada Pembuatan Biodiesel Melalui Proses Transesterifikasi
Authors: Harmiansyah  , Efendi Rustam , Muslimah Siti , Hikmawati Meli , Apriani Santi , Simbolon Sinober , Setiawan Wahyu
Published: July 2023

Biodiesel adalah bioenergi atau bahan bakar nabati yang dibuat dari minyak nabati (lemak hewani) melalui proses transesterifikasi. Transesterifikasi adalah proses reaksi (trigliserida) yang terkandung dalam minyak direaksikan dengan metanol dan dibantu oleh katalis alkali, sehingga menghasilkan biodiesel. Tujuan penelitian adalah mengetahui kualitas biodiesel pada katalis MeOH melalui proses transesterifikasi. Pada MeOH 20%, 25%, dan 30% didapatkan nilai Yield berturut-turut adalah 81,5%, 86,6%, dan 44,4%. Selain itu, pada penelitian ini juga dilakukan perhitungan densitas yang mempengaruhi dari kualitas biodiesel dari masing-masing jumlah MeOH yang digunakan didapatkan densitas sebesar 0,85 ð‘”/ð‘šð‘™. Sehingga dapat diketahui penggunaan katalis MeOH mempengaruhi kualitas hasil biodiesel.
THE DEFENCE MECHANISMS USED BY HYSTERIA MALAY STUDENTS IN KELANTAN TO PROTECT THEMSELVES FROM UNCOMFORTABLE BEHAVIOURS
Authors: Paramasivam Nagarubini , Kurniawan Yohan , A’dilah Fairuz
Published: July 2023

Malaysians frequently use the term hysteria to describe an illness caused by a subtle disturbance or ghost behaviour. The Malay community considers hysteria to be 'phantom ghost' or 'disturbed’. Such beliefs arose because the Malay community believed that the hysteria that occurred in girls and women was a symptom of ghosts, jinn, and satanic disturbances or anything related to disturbances of subtle and unseen things. The burden of mental illness in Malaysia is high, and it is increasing. Malaysian mental health-related burden comprises up to 37% of total disability. The National Health and Morbidity Survey (NHMS) 2015 revealed a prevalence of 29.2% of Malaysians above 16 years to have mental health problems, with three in ten Malaysians struggling with some form of mental health issues. From the perspective of looking after the future generations of Malaysians, the picture of adolescent mental health is also worrying. The objective of this study was to describe how the Malay students used defence mechanism to protect themselves from unpleasant behaviours. A qualitative approach, psychological tests and triangulation method were used for this study, in which 10 specific hysteria students was selected for in-depth interview. The psychological test were DASS-21 Test and Drawing Test. Snow ball sampling was used to select young girls in high schools who experienced mass hysteria. The results show that the hysteria respondents suffered from trauma, emotional problems, verbal abuse, sexual harassment, and a lacking of their parents’ attention. There are two types of problems: internal and external. The internal problem is their personality. The findings of the study may guide students in Kelantan to get proper treatment from medical professional. If mass hysteria in the Kelantan context is better understood, teachers can be empowered through health education to enable them to identify mass hysteria outbreaks in schools early, manage victims and observers more effectively and refer victims to health workers for treatment.
АНАЛІЗ ТЕХНОЛОГІЙ ФОТОЕЛЕКТРИЧНОГО ПЕРЕТВОРЕННЯ СОНЯЧНОГО ВИПРОМІНЮВАННЯ НА ЕЛЕКТРИЧНУ ЕНЕРГІЮ
Authors: Карпчук Г. Л. , Будько В. I.
Published: July 2023

Розвиток технологій відновлюваної енергетики з пере-творення енергії сонячного випромінювання на електричну зумовив значний приріст потужностей сонячної електроенергетики, а також спонукає постійно оновлювати прогнози з технічно досяжного потенціалу енергії Сонця при застосуванні фотоелектричного обладнання та устаткування нових поколінь. Мета цієї статті – проведення аналізу існуючих технологій фотоелектричного перетворення сонячного випромінювання на електричну енергію та перспективи їх використання. У роботі наведено аналіз трьох базових технологій перетворення сонячного випромінювання на електричну енергію: термодинамічну, фотоелектричну та комбіновану. Аналіз технологій термодинамічного перетворення енергії сонячного випромінювання показує свою ефективність при переважанні прямого сонячного випромінювання, що в умовах України спостерігається тільки в південних регіонах. З огляду на це більш деталізовано розглянуто технології фотоелектричного перетворення для чотирьох поколінь: кремнієвих, тонкоплівкових, барвникових та перовскітових, які найбільше підходять для помірних широт нашої країни. Усі вони мають відмінності за електричними параметрами, технологією виробництва, матеріалами та ефективністю. Для цих фотоелектричних технологій у роботі наведено математичні залежності, які дають змогу визначити електричні характеристики, параметри для їх порівняння між собою та структурні схеми для наочного зображення відмінностей між ними. Розглянуто досягнення в розробці фотоелектричних технологій за даними провідних світових лабораторій у сфері фотоенергетики, які демонструють сталий розвиток сонячних електричних технологій і підвищення ефективності їх роботи. Наукові положення та висновки, що сформульовані в роботі, базуються на проведених теоретичних дослідженнях, які надають обґрунтування подальшого вивчення теоретично та практично досяжного потенціалу перетворення сонячної енергії на електричну.
An Ecocritical Reading of Selected Poems of Nnimmo Bassey’s We Thought it was Oil but it was Blood
Authors: Keghtor Akosu, Solomon
Published: July 2023

This paper presents an ecocritical analysis of Nnimmo Bassey's poetry collection, "We Thought It Was Oil but It Was Blood" (2002). Focusing on contemporary issues in the Niger Delta Region of Nigeria, the collection delves into themes of environmental degradation, despoliation, and the abuse of nature, including the landscape, flora, and fauna. Employing ecocriticism as a theoretical framework, this study conducts a contextual analysis of the poetry collection. Additionally, the paper evaluates the literary elements employed in the text, highlighting their significance for literary research. The findings suggest that the ecocritical reading of the text raises pertinent questions about human interactions with nature and enhances readers' awareness of the natural world and its interconnectedness with it.
Karakteristik Fisik, Kimia dan Sensoris Kerupuk Keong Mas (Pomacea canaliculata)
Authors: Apriyani Apriyani , Widiastuti Indah , Syafutri Merynda Indriyani
Published: July 2023

The objective of this research was to know the physical, chemical and sensory characteristics of snail crackers. The research used factorial randomized block design with difference formulation of snail meat and water as treatments; each treatment was replicated three times. The treatments were the formulation of snail meat (40%, 50%, 60%, 70%, and 80%) and water (60%, 50%, 40%, 30% and 20%). Parameters of research were physical characteristic (fracture, the percentage of expansion, lightness, chroma, and hue), chemical characteristic (water, ash, fat, protein, and carbohydrate by difference content), and sensory characteristic (hedonic test about aroma, colour, fracture and taste). The result showed that the average of fracture ranges from 618.53 gf to 1735.87 gf, the percentage of expansion ranges from 117.67% to 44.17%, lightness ranges from 75.23% to 66.6%, chroma ranges from 9.27% to 13.73%, hue ranges from 89.27o to 79.23o, water content ranges from 2.21% to 2.86%, ash content ranges from 1.39% to 3.03%, fat content ranges from 5.99% to 11.45%, protein content ranges from 3.78% to 7.58%, carbohydrate by difference content ranges from 75.09% to 86.64 % and hedonic test: aroma ranges from 2.8 to 2.84, colour ranges from 2.72 to 3.52, fracture ranges from 2.92 to 3.32 and taste ranges from 2.48 to 3.44. The best treatment of snail crackers was B treatment of formulation of snail meat 50% and water 50%
Karakteristik Edible Film Gelatin-Kitosan dengan Tambahan Ekstrak Genjer (Limnocharis flava) dan Aplikasi pada Pempek
Authors: Ali Haidir , Baehaki Ace , Lestari Shanti Dwita
Published: July 2023

The purpose of this research was to observed the effects of yellow velvetleaf fruit estrats on the characteristics fruit extracts on the characteristics of gelatin-chitosan edible film and its application in pempek. The ability of film to inhibit the spoilage of pempek was also studied. This research used a Randomized Block Design (RBD) in the first stage and Design Randomized Factorial (DRF) in the second stage with two-factor and two repetitions. Factors treatment consists of velvetleaf extract concentrations (0, 10, 20%) and the storage time (0, 1, 2 days). The first phase edible film was characterized basedon solubility, thickness, water vapor transmission and the percent extension, the second phase while their ability to protect pempek produk were assessed though the changes on water content, total volatile base-N (TVB-B), total plate count (TPC) yeasts and molds of the products during storage 2 days. The results of the first phase of research showed the addition of extract yellow velvetleaf no significant effect on the solubility, thickness and water vapor transmission while give the significant effect on the percent extension. The results of the second phase research showed the interaction between the addition of yellow velvetleaf extract and storage time significant effect on water content, total plate count (TPC) and yeast fungi while the total volatile base-N (TVB-N) effect is no significant effect. The best treatment of the first study, was A1 (Extra yellow velvetleaf 10%). Activity antimicrobe, Solubility, thickness, water vapor transmission and the percent extension of each is 3.75mm, 98.14%, 0.18 mm, 7.40 g/m2.24jam, 63.66%. The best treatment of the second study is A1B1 (extract yellow velvetleaf 0% and first day of storage time). Water content, total volatile base-N (TVB-N), total plate count (TPC) yeasts and molds, respectively 54.68%, 9.3 mg/100 g, 7.22x103 CFU/g, and 5.32x104 CFU/g.
A Survey on Embedding Iris Biometric Watermarking for User Authentication
Authors: Taskeen Taj  , Manash Sarkar
Published: July 2023

This paper proposes an innovative approach called "Embedding Iris Biometric Watermarking" for user authentication. By utilizing the unique characteristics of the iris, a secure watermark is generated and embedded into the biometric data. This technique enhances the security and robustness of authentication systems, offering advantages such as high security, resistance to attacks, and non-intrusiveness. The proposed method has potential applications in access control, secure transactions, and digital rights management, providing a reliable solution for ensuring the integrity and confidentiality of digital systems and services.
Pementasan Musik Genggong di Desa Batuan Kabupaten Gianyar
Authors: Saputra I Kadek Bharata Dwyq , Temon Astawa I Nyoman , Sukerni Ni Made
Published: July 2023

Bali is known for its arts, culture, and traditions because every tradition and culture is always based on Hinduism and does not leave the local culture that already exists in the area. One of them is the performance of genggong music in Batuan Village, Sukawati District, Gianyar Regency. This study aimed to determine: (1) the form of genggong music performance in Batuan Village, Sukawati District, Gianyar Regency. (2) The function of Genggong Music Performance in Batuan Village, Sukawati District, Gianyar Regency. (3) The values of Hindu religious education are contained in the genggong music performance in Batuan Village, Sukawati District, Gianyar Regency. The method used to collect data is observation, interviews, documentation, and literature study. The data analysis technique in this study was through three stages, namely descriptive, data reduction, and conclusion drawing. The result shows: (1) there are several stages in playing genggong music, playing techniques, the duties of each instrument and the composition of the musicians in genggong music performances. (2) The functions of genggong music performance in Batuan Village, Sukawati District, Gianyar Regency, namely social functions, aesthetic functions, expressive functions, and cultural preservation. (3) The value of Hindu religious education contained in the genggong music performance in Batuan Village, Sukawati District, Gianyar Regency, namely the value of religious education, the value of ethical education (morals), the value of event education, the value of social education and cultural values. Based on the results of the study, it can be concluded that the genggong music performance is the work of the "pengangon” (shepherd). On the other hand, some say that the term genggong comes from the sound produced by the instrument when it is exhaled. The sound produced from these gusts is “ngeng” and “ngoring” so the instrument is named genggong.
The Impact of Preferential Taxation on the Stimulation of Investment Processes in Ukraine in the Context of the Experience of EU Member States
Authors: Rudenko Viktoriia , Pohrishchuk Halyna , Moskvichova Olena , Hryhoruk Iryna
Published: July 2023

In modern conditions, one of the main tasks of the fiscal mechanism is to create favorable conditions for maintaining and activating investment processes at the micro level. Thanks to tax incentives as a leading element of the fiscal mechanism, the state influences the amount of financial resources that are at the disposal of taxpayers − legal entities and individuals - and can be used for investment. Therefore, the purpose of the study was to evaluate the use of tax incentives to ensure the investment development of enterprises and households in EU member states and in Ukraine; to conduct SWOT analysis of investment tax incentives, and to find opportunities to further improve of their management. The study substantiates the content of tax incentives and the conditions of their use to activate investment processes at the micro level. The experience of EU member states in the use of different ways of tax stimulation of investments of legal entities and individuals is generalized. The tax incentives introduced in Ukraine are considered and the key problems of their existence are described in the context of stimulating the investment activity of taxpayers. SWOT analysis of investment tax incentives was carried out, which helped to identify the positive and negative impact of the external and internal environment on their implementation. The necessity and principles of management of investment preferential taxation are established. Improvement of the management of providing investment tax incentives in Ukraine is proposed on the basis of taking into account the experience of EU member states. It has been proven that the purposeful use of tax incentives stimulates the investment activity of households and economic entities, so Ukraine’s use of the experience of EU countries to solve the problems of providing tax incentives to individuals and legal entities will eventually lead to the intensification of investment processes at the micro level.
Estrategia pedagógica para promover valores ambientales frente a la deforestación en estudiantes de primaria en la I.E Panamericana de Icononzo Tolima
Authors: Chala Herrera Jenny Rocio , Montealegre Giraldo Jose Fernando
Published: July 2023

Esta investigación titulada Estrategia pedagógica para promover valores ambientales frente a la deforestación en estudiantes de primaria en la I.E Panamericana de Icononzo Tolima, tiene como propósito general de la investigación, mitigar la deforestación en la vereda de Boquerón Tolima  provocada por diferentes prácticas de la comunidad, pero especialmente  la generada por el proyecto de  la obra del tercer carril Bogotá Girardot  en el kilómetro 15 Bogotá Melgar. El enfoque de la investigación es cualitativo, el alcance es  descriptivo y el diseño utilizado fue el de participación acción, la muestra cuenta con una población aproximada de 30 estudiantes  a nivel primaria de la Institución Educativa Panamericana, ubicada en la vereda Boquerón, situada en el municipio de Icononzo departamento del Tolima. La técnica que se utilizó fue la de la entrevista y el instrumento un guion de entrevista el primero para realizar un diagnóstico con relación a los conocimientos ambientales que tienen los estudiantes, y un guion de entrevista final, para evaluar el impacto de la estrategia pedagógica a ejecutar, una vez implementada se logró mejorar el conocimiento y practicas por parte de los estudiantes objeto de estudio.
DEVELOPMENT OF A QUALITY MANAGEMENT SYSTEM FOR PRECAST CONCRETE FACTORIES
Authors: Seo Wonseok , Choi Byungjoo , Shin Dongyoun , Kim Jinyoung
Published: July 2023

The precast concrete (PC) method involves manufacturing reinforced concrete building components in a factory that are then transported to and assembled on a construction site. Compared to conventional methods, PC is widely employed as an advantageous means of creating a sustainable environment and improving construction quality. However, due to time and cost increase, many modern PC factories inspect only randomly selected component samples, for which they write inspection reports using paper-based forms. The storage and management of these documents associated with inspections within factories are essential because any defects that occur during the manufacturing process adversely affect the subsequent delivery and assembly activities. In this study, a mobile application capable of automated documentation and the storage, and input of systematic data was developed to generate a system for comprehensive quality management and assurance within PC factories. The developed system was tested in a PC factory, achieving a 47% time-saving rate compared to the conventional inspection method. Inspection reports of the developed system contain considerably more information than those of the conventional method and fundamentally prevent the risk of document damage and loss as they are automatically archived on a server in digital format.
Assessing the Accuracy of TESS Asteroseismology with APOGEE
Authors: Theodoridis Artemis Theano , Tayar Jamie
Published: July 2023

The recent NASA TESS mission has the potential to increase the available asteroseismic sample dramatically, but its precision and accuracy have yet to be confirmed. To date, NASA’s Kepler mission has been considered the gold standard for asteroseismic samples, despite data only being available for a small portion of the sky. TESSs observations cover the whole sky, and previous work has identified 158,000 potential red giant oscillators. Using APOGEE, which is calibrated to the asteroseismic scale of the Kepler data, we show that seismology from TESS is calibrated to the Kepler scale to better than 5% for about 90% of red giants, and has only slight trends with mass, metallicity, and surface gravity. We therefore conclude that current TESS seismic results can already be used for galactic archeology, and future results are likely to be highly transformational to our understanding.
La vestizione delle persone significative durante lâ€™accesso alle visite ai pazienti adulti ricoverati in terapia intensiva. Entriamo nel merito (e nel metodo).
Authors: Bambi Stefano , Lucchini Alberto , Trevisan Monica , Piemonte Guya , Manici Matteo , Comisso Irene , Marchese Filippo , Mattiussi Elisa , Elli Stefano , Fusi Cristian , Bulleri Enrico , Negro Alessandra , Rasero Laura , Iozzo Pasquale
Published: July 2023

Il concetto di terapia intensiva aperta prevede lâ€™abbattimento delle barriere fisiche, comunicative e temporali rispetto al precedente modello di cura in area critica. A questi tre principi si stanno affiancando nuove sfide: la partecipazione dei familiari alle attivitÃ  di nursing e al round di visita medica sul paziente. Al momento, perÃ², rimangono aperte alcune importanti questioni, la mancata risposta alle domande che si pongono ancora oggi dietro il falso mito che vede il familiare come attore di interferenze con le cure e lâ€™assistenza al paziente, e come portatore di infezioni alla persona oggetto delle visite. Lâ€™obiettivo del presente articolo Ã¨ rilevare la presenza di evidenze scientifiche alla base delle attuali raccomandazioni sulle pratiche di vestizione dei visitatori in terapia intensiva.
Intrathyroidal metastasis of tonsillar squamous cell carcinoma masquerading as a primary thyroid tumor
Authors: Go Jai-Hyang
Published: July 2023

Intrathyroidal metastasis of tonsillar squamous cell carcinoma is rare. To date, only six cases have been reported in the literature. This case was unusual and presented with thyromegaly before the diagnosis of the primary tumor. A 55-year-old male patient was suspected to have a primary thyroid tumor with nodal metastasis. The thyroid gland was diffusely enlarged, with no discernible mass. Histologically, the thyroid parenchyma revealed extensive endolymphatic tumor emboli, which were positive for p40 and p16 in a background of chronic lymphocytic thyroiditis. Positron emission tomography–computed tomography revealed hypermetabolic activity in the right tonsillar region. Tonsillar biopsy revealed human papillomavirus–positive squamous cell carcinoma. The present case is the first reported case of intrathyroidal metastasis of tonsillar squamous cell carcinoma with an initial clinical presentation of thyroid enlargement before the primary tumor of tonsillar cancer was diagnosed.
Editorial
Authors: HADDAM BOUABDALLAH Faiza , CHIALI Ramzi
Published: July 2023

Multilingualism and Intercultural Diversity in Didactics: Challenges and StrategiesPlurilinguisme, diversité culturelle et identité(s) : enjeux et perspectives didactiques

Guest edited byDr Faiza Haddam BouabdallahandDr Ramzi Chiali
PENGARUH GERAKAN LITERASI SEKOLAH TERHADAP PENINGKATAN MINAT BACA SISWA KELAS IV SD NEGERI 2 LANDUNGSARI
Authors: Nur Alfiana Dewi Rizka , Nurazizah Rifqi Aulia , Arviana Via
Published: July 2023

The aim of this research was to find the influence of Gerakan Literasi Sekolah (GLS) towards students’ reading interest in fourth grade of SDN 2 Landungsari. By applying 15 minutes reading before learning, this research was expected to increase students’ reading interest which was still categorized as low. The research method used was descriptive quantitative with associative approach. Fourth grader students of SDN 2 Landungsari was the population of this research consist of 17 students. This research was using population study which the subject was the whole population of fourth grader students of SDN 2 Landungsari. The data collected by distributing multiple choice and essai Pre-test and Post test questions. The data was analyzed by using ANOVA simple linear regression analysis in SPSS 25 for Windows. The result shows that there was a significant effect from Gerakan Literasi Sekolah (GLS) on increasing students’ of fourth grade reading interest at SDN 2 Landungsari, Dau, school year 2022/2023.
PERSPECTIVAS E DESAFIOS DO AGRONEGÓCIO BRASILEIRO FRENTE AO MERCADO INTERNACIONAL
Authors: Paim Rifan Quintam Carlos , Assunção Gerfison Maico de
Published: July 2023

O agronegócio brasileiro desempenha um papel fundamental na economia do país, sendo importante no suprimento de alimentos tanto para o mercado interno como para o mercado internacional. No entanto, enfrenta diversos desafios nesse contexto global. Com o objetivo de compreender esses desafios, este estudo realizou uma revisão de literatura, analisando publicações relevantes sobre o tema. A metodologia adotada consistiu na busca e análise de artigos científicos, relatórios e outras fontes de informação relacionadas ao agronegócio brasileiro no mercado internacional. Foram considerados aspectos como definição e características do agronegócio brasileiro, importância econômica, produtos agrícolas e pecuários exportados, fatores de competitividade, impacto socioambiental, acordos comerciais e tecnologia. Os resultados da pesquisa revelaram que o agronegócio brasileiro possui potencial significativo para atender à crescente demanda global por alimentos, graças às suas extensas áreas de terras agricultáveis e clima favorável. No entanto, enfrenta desafios como barreiras comerciais e sanitárias, preocupações socioambientais e a necessidade de adoção de tecnologia e inovação para manter sua competitividade. Conclui-se que o agronegócio brasileiro desempenha um papel estratégico na economia do país, mas é necessário enfrentar os desafios do mercado internacional. É fundamental adotar práticas sustentáveis, superar barreiras comerciais e sanitárias, buscar acordos comerciais favoráveis e investir em tecnologia e inovação. Essas medidas são essenciais para garantir o crescimento e a competitividade do setor, contribuindo para o desenvolvimento econômico e sustentável do Brasil no mercado global de alimentos.
Elektronički potpis, elektronički pečat i elektronički vremenski žig - mjesto i uloga u hrvatskom zakonodavstvu
Authors: Terze Nika
Published: July 2023

Novim zakonodavnim okvirom u Republici Hrvatskoj pojmovi elektronički popis, elektronički pečat i elektronički vremenski žig dobivaju središnju ulogu u djelovanju tijela državne vlasti, drugih državnih tijela, jedinica lokalne i područne (regionalne) samouprave te pravnih osoba s javnim ovlastima, odnosno javnopravnih tijela. Međutim, postavlja se pitanje koliko su navedena tijela spremna transformirati svoj dosadašnji model rada i prilagoditi se promjenama koje novi zakonodavni okvir uvodi. Preduvjete za navedene zakonodavne promjene postavila je Europska unija svojom legislativom obvezatnom u svim državama članicama. Također, jedan od najvećih izazova koji se pojavljuje je nepoznavanje navedenog zakonodavnog okvira, njegovih odredbi te značenja, odnosno pravne snage pojmova elektronički potpis, elektronički pečat i vremenski žig. Sukladno tome, u ovom radu pobliže se objašnjava njihovo značenje u okviru zakonodavstva Europske unije i Republike Hrvatske.
Sarcopenia in end-stage liver disease and after liver transplantation
Authors: Leunis S , Vandecruys M , Van Craenenbroeck A.H. , Cornelissen V , Bogaerts S , De Smet S , Monbaliu D
Published: July 2023

Sarcopenia occurs in 30-70% of patients with end-stage liver disease and is associated with inferior pre- and post-liver transplant outcomes such as prolonged intubation times, long intensive care and hospitalization times, heightened risk of post-transplant infection, reduced health-related quality of life, and increased rates of mortality. The pathogenesis of sarcopenia is multifactorial and involves biochemical disturbances such as hyperammonemia, low serum concentrations of branched-chain amino acids (BCAAs) and low serum levels of testosterone, as well as chronic inflammation, inadequate nutritional status, and physical inactivity. Prompt recognition and accurate assessment of sarcopenia are critical and require imaging, dynamometry, and physical performance testing for the assessment of its subcomponents: muscle mass, muscle strength, and muscle function, respectively. Liver transplantation mostly fails to reverse sarcopenia in sarcopenic patients. In fact, some patients develop de novo sarcopenia after undergoing liver transplantation. The recommended treatment of sarcopenia is multimodal and includes a combination of exercise therapy and complementary nutritional interventions. Additionally, new pharmacological agents (e.g. myostatin inhibitors, testosterone supplements, and ammonia-lowering therapy) are under investigation in preclinical studies. Here, we present a narrative review of the definition, assessment, and management of sarcopenia in patients with end-stage liver disease prior to and after liver transplantation.
Motorized spiral enteroscopy: effectiveness when used for new indications
Authors: Colin H , Donati A , Monino L , Moreels T.G.
Published: July 2023

Background and study aims: Motorized spiral enteroscopy is proven to be effective in antegrade and retrograde enteroscopy. Nevertheless, little is known about its use in less common indications. The aim of this study was to identify new indications for the motorized spiral enteroscope.

Methods: Monocentric retrospective analysis of 115 patients who underwent enteroscopy using PSF-1 motorized spiral enteroscope between January 2020 and December 2022.

Results: A total of 115 patients underwent PSF-1 enteroscopy. 44 (38%) were antegrade procedures and 24 (21%) were retrograde procedures in patients with normal gastrointestinal anatomy with conventional enteroscopy indications. The remaining 47 (41%) patients underwent PSF-1 procedures for secondary less conventional indications: n=25 (22%) enteroscopy-assisted ERCP, n=8 (7%) endoscopy of the excluded stomach after Roux-en-Y gastric bypass, n=7 (6%) retrograde enteroscopy after previous incomplete conventional colonoscopy and n=7 (6%) antegrade panenteroscopy of the entire small bowel. In this group of secondary indications, technical success rate was significantly lower (72.5%) as compared to technical success rates in the conventional groups (98-100%, p<0.001 Chi-square). Minor adverse events occurred in 17/115 patients (15%), all treated conservatively (AGREE I and II).

Conclusion: This study demonstrates the capabilities of PSF-1 motorized spiral enteroscope for secondary indications. PSF-1 is useful to complete colonoscopy in case of long redundant colon, to reach the excluded stomach after Roux-en-Y gastric bypass, to perform unidirectional pan-enteroscopy and to perform ERCP in patients with surgically altered anatomy. However, technical success rates are lower as compared to conventional antegrade and retrograde enteroscopy procedures, with only minor adverse events.
Lahar events in the last 2,000 years from Vesuvius eruptions. Part 3: Hazard assessment over the Campanian Plain
Authors: Sandri Laura , de' Michieli Vitturi Mattia , Costa Antonio , Di Vito Mauro Antonio , Rucco Ilaria , Doronzo Domenico Maria , Bisson Marina , Gianardi Roberto , De Vita Sandro , Sulpizio Roberto
Published: July 2023

Abstract. In this study we present a novel general methodology for Probabilistic Volcanic Hazard Assessment (PVHA) for lahars. We apply the methodology to perform a probabilistic assessment in the Campanian Plain (Southern Italy), focussing on syn-eruptive lahars from a reference-size eruption from Somma-Vesuvius. We take advantage of new field data relative to volcaniclastic flow deposits in the target region and recent improvements in modelling lahars. We explore the effect of uncertainty on the flow initial conditions on the invasion of lahar in the target area, by sampling coherent sets of values for the input model parameters and performing a large number of simulations. We analyse the simulation outputs to produce hazard curves, hazard maps and probability maps for the maximum flow thickness, and hazard surface and probability maps for joint thresholds in flow thickness and dynamic pressure. We believe the latter hazard products represent, on one hand, a novel product in PVHA for lahars, and, on the other hand, a useful means for impact assessment.
WRF (v4.0)-SUEWS (v2018c) Coupled System: Development, Evaluation and Application
Authors: Sun Ting , Omidvar Hamidreza , Li Zhenkun , Zhang Ning , Huang Wenjuan , Kotthaus Simone , Ward Helen C. , Luo Zhiwen , Grimmond Sue
Published: July 2023

Abstract. The process of coupling the Surface Urban Energy and Water Scheme (SUEWS) into the Weather research and forecasting (WRF) model is presented, including pre-processing of model parameters to represent spatial variability of surface characteristics. Fluxes and mixed layer height observations in the southern UK are used to evaluate a two-week period in each season. Mean absolute errors, based on all periods, are smaller in residential Swindon than central London for turbulent sensible and latent heat fluxes (QH, QE) with greater skill on clear days at both sites (for incoming and outgoing short- and longwave radiation, QH and QE). Clear seasonality is seen in the model performance: with better absolute skill for QH and QE in autumn and winter, when there is a higher frequency of clear days, than in spring and summer. As the WRF-modelled incoming shortwave radiation has large errors, we apply a bulk transmissivity derived from local observations to reduce the incoming short-wave radiation input to the land surface scheme – this could correspond to increased presence of aerosols in cities. We use the coupled WRF-SUEWS system to investigate impacts of the anthropogenic heat flux emissions on boundary layer dynamics by comparing areas with contrasting human activities (central-commercial and residential areas) in Greater London - larger anthropogenic heat emissions not only elevate the mixed layer heights but also lead to a warmer and drier near-surface atmosphere.
ТАЛШЫҚТЫ БРЭГГ ТОРЛАРЫН ҚОЛДАНУ АЯСЫ ЖӘНЕ ОЛАРДЫ ПАЙДАЛАНУ МҮМКІНДІКТЕРІ
Authors: Кадирбаева Гулим , Чежимбаева Катипа , Вуйцик Вальдемар , Хизирова Мухаббат
Published: July 2023

Қазіргі кезде талшықты оптикалық байланыс желілерінің пайдалану ауқымы артқан сайын, желінің жұмыс жасауын бақылайтын көмекші құралдар мен құрылғылар – талшықтың сыртқы ортаның әсерінен болған қысымына және ортаның температурасына тәуелділігін анықтау маңыздылығы артуда. Мақалада талшықты Брэгг торына (ТБТ) негізделген температуралық және деформациялық сенсорларды үлкен қашықтықта орналасқан және қауіпті әртүрлі жарылғыш, күшті электромагниттік сәуле шығаратын орталарда, мұнай, газ құбырларындағы температура мен қысымды өлшеуге, магистралды талшықты байланыс желісі жүргізілген орталардағы температураны анықтау мақсатында кеңінен қолданатындылығы сипатталады. Сонымен қатар, Брэгг толқын ұзындығының ығысуының деформацияға және де температураға тәуелділігі көрсетілді. Жұмыста жалпы талшықты Брэгг торларының маңыздылығы, сонымен бірге оларлдың байланыс салаларында қолданылуы көрсетілді. Жұмыстың негізгі мақсаты -  талшықты Брэгг торларымен таныстыру , жалпы ұғымдар және талшықты брэгг торларын қолдану аясы және оларды пайдалану мүмкіндіктерін көрсету болып табылады.
ҚАЗАҚСТАННЫҢ ТЕМІРЖОЛ ӨТКЕЛДЕРІНДЕГІ АВАРИЯЛЫҚ ЖАҒДАЙЛАРДЫ ТАЛДАУ
Authors: Сансызбай Қанибек , Бахтиярова Елена , Батырханов Муслим , Тасболатова Лаура , Сагмединов Данияр
Published: July 2023

Мақала пайдаланылған жүйелер мен олардың элементтерінің физикалық және моральдық тозуына, көлік ағынының қарқындылығы мен тығыздығының артуына, апаттық жағдайлардың көбеюіне және т. б. байланысты туындайтын теміржол переездеріндегі проблемалық мәселелерді шешуге бағытталған. Теміржол инфрақұрылымында теміржолдардың автомобиль жолдарымен бір деңгейде қиылысу орындары ең қауіпті және күрделі учаскелер болып табылады, өйткені теміржол және автомобиль көліктерінің тиімділігі олардың қауіпсіз және ақаусыз жұмыс істеуіне байланысты. Қазіргі уақытта қозғалыс жылдамдығының және жылжымалы құрамның массасының артуына, сондай-ақ автомобильдер паркінің ұлғаюына байланысты күзетілетін және күзетілмейтін переездердегі жағдайлардың өзгеруі байқалады. Авариялық жағдайлардың өсуі, істен шығу санының артуы байқалады. Мақалада соңғы 5 жылдағы Қазақстан Республикасындағы теміржол переездеріндегі авариялық жағдайларға талдау жасалады, шет елдердің теміржол переездеріндегі жағдайларға және олардың бар проблемаларды шешу жолдарын іздеудегі тәжірибесіне талдау жасалады. Мақалада жылжымалы автоматиканың дамыған моделі зерттеледі, онда оның бес негізгі торабы ұсынылған, олардың ақаулары қозғалыстың қауіпсіздігіне қауіп төндіруі мүмкін. Сондай-ақ, переездік инфрақұрылымның негізгі объектілерінде қауіпсіздікті бұзу тәуекелдерін айқындау мақсатында переездік құрылғылардың өзара іс-қимыл моделі салынды.
Extraction of Alkaloids from Colocynthis vulgaris (L.) Schrader harvested in Oued N’sa (Ouargla region)
Authors: Benkhira Latra , Chaouch Noura
Published: July 2023

Plants constitute a vital component of the biodiversity as they play a key role in maintaining earth’s environmental equilibrium and ecosystem stability. Herbal medicine is known to be the oldest form of healing, dating back to ancient Greece (1600 BC). It involves the use of plant to improve, maintain or restore health and wholeness. Phytochemicals are bioactive chemicals of plant origin. They are regarded as secondary metabolites synthesized in all parts of the plant body. The quantity and quality of phytochemicals present in plant parts may differ from one part to another. In fact, there is a lack of information on the distribution of the biological activity in different plant parts mainly due to the difference in distribution of active compounds which are more frequent in some plant parts than in others. Colocynthis vulgaris (L) Schrader is one of the medicinal plants of the Cucurbitaceae family, widespread in Algeria mainly in Ouargla in the region of Oued N'sa. This plant is used in traditional medicine for the treatment of several diseases. Its multiple pharmacological properties are due to its richness in active substances, especially alkaloids. The main objective of this study is the comparison between two extraction protocols of alkaloids, one in acid medium and the other in an alkaline medium. The results obtained confirm the plant's richness in alkaloids and the efficiency of the extraction protocol in acid medium.
Ethnopharmacological properties of the fern Adiantum lunulatum: A Review
Authors: Sravani T , Sunitha K.
Published: July 2023

Adiantum lunulatum (Hamsapadhi) is a cosmopolitan tropical fern that is traditionally employed in folklore medicine to address various maladies. The fern is a reservoir for major plant secondary metabolites like tannins, saponins, alkaloids, phenolics flavonoids, etc. Accredited the presence of phytochemicals the fern portrays pharmacological properties like antimicrobial, antifertility, hepatoprotective, anti-ulcerative, antipyretic, gastroprotective properties, etc. Despite numerous evidences of pharmacological applications in traditional medicines, there are very few in vitro and in vivo studies on the fern to corroborate its pharmacological properties and to appraise it as a prospective therapeutic agent, thus necessitating more research in this fern. The current review circumscribes the phytochemistry of the fern and its concomitant pharmacological properties.