bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving the storage quality and suppressing off-flavor generation of winter jujube by precise micro-perforated MAP
Authors: Cui Xinzhi , Ding Yibing , Sun Chanchan , Li Xiulian , Yuan Shuzhi , Guo Fengjun , Zeng Xiangquan , Fan Xinguang , Sun Shuyang
Published: April 2024

Introduction

Traditional modified atmosphere packaging (MAP) cannot meet the preservation requirements of winter jujube, and the high respiration rate characteristics of winter jujube will produce an atmosphere component with high CO2 concentration in traditional MAP. Micro-perforated MAP is suitable for the preservation of winter jujube due to its high permeability, which can effectively remove excess CO2 and supply O2. In this study, a microporous film preservation system that can be quickly applied to winter jujube was developed, namely PMP-MAP (precise micro-perforated modified atmosphere packaging). An experiment was designed to store winter jujube in PMP-MAP at 20°C and 2°C, respectively. The quality, aroma and antioxidant capacity, etc. of winter jujube at the storage time were determined.

Methods

In this study, the optimal micropore area required for microporous film packaging at different temperatures is first determined. To ensure the best perforation effect, the effects of various factors on perforation efficiency were studied. The gas composition within the package was predicted using the gas prediction equation to ensure that the gas composition of the perforated package achieved the desired target. Finally, storage experiments were designed to determine the quality index of winter jujube, including firmness, total soluble solids, titratable acid, reddening, and decay incidence. In addition, sensory evaluation, aroma and antioxidant capacity were also determined. Finally, the preservation effect of PMP-MAP for winter jujube was evaluated by combining the above indicators.

Results and discussion

At the end of storage, PMP-MAP reduced the respiration rate of winter jujube, which contributed to the preservation of high total soluble solids and titratable acid levels, and delayed the reddening and decay rate of winter jujube. In addition, PMP-MAP maintained the antioxidant capacity and flavor of winter jujube while inhibiting the occurrence of alcoholic fermentation and off-flavors. This can be attributed to the effective gas exchange facilitated by PMP-MAP, thereby preventing anaerobic stress and quality degradation. Therefore, the PMP-MAP approach is an efficient method for the storage of winter jujube.
The mediating role of anxiety in the relationship between misophonia and quality of life: findings from the validated Turkish version of MisoQuest
Authors: Ay Ezgi , Huviyetli Mert , Çakmak Eda
Published: April 2024

Introduction

Misophonia is a disorder characterized by decreased tolerance to certain sounds or their associated stimuli, and many measurement tools have been developed for its diagnosis and evaluation. The aims of the current study were to develop the Turkish version of MisoQuest, a fully validated misophonia questionnaire, to evaluate the relationships between misophonia, anxiety, and quality of life, and to examine the mediating role of anxiety in the relationship between misophonia and quality of life.

Methods

The reliability of the Turkish version of MisoQuest was conducted using data from 548 participants (Mean age = 28.06 ± 9.36). Then, the relationships between misophonia, anxiety, and quality of life were evaluated in a separate sample of 117 participants (Mean age = 25.50 ± 6.31) using the State–Trait Anxiety Inventory (STAI) and the Short Form 36 (SF-36) questionnaire.

Results

The results showed that the Turkish version of MisoQuest has good psychometric properties. Close-to-moderate positive correlations were found between misophonia and anxiety, and weak negative correlations were found between misophonia and quality of life. Anxiety mediated the relationships between misophonia and quality of life.

Discussion

These results emphasize that misophonia may be an important problem affecting people’s quality of life and reveal the mediating role of anxiety on this effect.
Stalking, harassment, gendered abuse, and violence towards politicians in the COVID-19 pandemic and recovery era
Authors: Every-Palmer Susanna , Hansby Oliver , Barry-Walsh Justin
Published: April 2024

Background

High levels of harassment and threats against parliamentarians are being reported internationally, especially in the social media space. This is occurring alongside changes in our social landscape, with increasing political polarisation and the ongoing ramifications from the COVID-19 pandemic. Harassment of politicians has been shown to have implications for psychological wellbeing and physical safety.

Objectives

To investigate harassment and violence towards parliamentarians in the COVID-19 pandemic and recovery era, including whether there had been a change in its nature and quantity, and to explore the contribution of social media.

Methods

A survey of all New Zealand’s parliamentarians was fielded in 2022, focusing on their experiences of harassment analysed quantitatively and with manifest and latent content analysis of free text responses. Data were disaggregated and compared by gender. Secondary analyses were conducted on similar data collected from parliamentarians in 2014 to compare trends over time.

Findings

We obtained a cleaned achieved survey sample of 54 Members of Parliament (MPs). Harassment was reported by 98% of respondents, ranging from disturbing communication to actual physical violence. The vast majority of MPs endorsed multiple modalities of harassment occurring on multiple occasions. Ninety-six percent of MPs had been harassed over social media, with over half being threatened, including threats of physical violence (40%), sexual violence (14%), threats made towards MP’s family members (19%), threats towards staff (12%), and death threats (27%). Almost all forms of harassment had increased significantly since 2014. Most MPs reported experiencing abuse related to the Government response to the COVID-19 pandemic (e.g. lockdowns and vaccine mandates). Many MPs commented that the frequency and intensity of abuse increased markedly during the COVID pandemic and had not subsequently abated. Women were at significantly higher risk of certain types of social media harassment including gendered abuse, sexualised comments, threat of sexual violence, and threats toward their family.

Conclusion

Harassment of parliamentarians is an escalating issue. Online threats and misogyny are increasingly apparent. This harassment has significant psychosocial costs for victims, their family and staff, and for democratic processes.
Becoming a first-time father during the COVID-19 pandemic in France
Authors: Jean-Dit-Pannel Romuald , Belot Rose-Angélique , Mellier Denis , Robert Laura , Petersen Célia , Dinet Benoît , Bréhat Cécile , Koliouli Flora
Published: April 2024

The role of fathers in Western societies has undergone significant change over time. However, their psychopathology remains largely misunderstood and difficult to identify. This study aims to explore the lived experiences of first-time fathers during the COVID-19 pandemic. Twenty-seven first-time French fathers were recruited for the study, which involved a narrative interview, the Rorschach projective test, the Edinburgh Postnatal Depression Scale (EPDS), and a semi-structured interview. Narrative interviews revealed several challenges faced by these fathers, including the pressure of paternal responsibility, the need to be actively involved in the prenatal activities and caregiving (haptonomy, skin-to-skin contact), and concerns about the future of their couple and family as a triad. The Rorschach tests showed numerous perinatal responses and difficulties in identifying phallic representations among the fathers. Additionally, the EPDS scores indicated that 15% of fathers showed signs of depression, while 52% exhibited signs of anxiety. This study also examines the impact of the COVID-19 pandemic and its associated health context on creating the initial triad. Lastly, the case of one father is presented to illustrate the need for diagnostic tools to address the psychopathology of fathers, as narrative or semi-structured interviews have often fallen short of addressing this issue.
Eye movements as predictor of cognitive improvement after cognitive remediation therapy in patients with schizophrenia
Authors: Zhu Jiahui , Li Jinhao , Zhou Li , Xu Lingzi , Pu Chengcheng , Huang Bingjie , Zhou Qi , Lin Yunhan , Tang Yajing , Yang Liu , Shi Chuan
Published: April 2024

Aim

Baseline cognitive functions of patients predicted the efficacy of cognitive remediation therapy (CRT), but results are mixed. Eye movement is a more objective and advanced assessment of cognitive functions than neuropsychological testing. We aimed to investigate the applicability of eye movements in predicting cognitive improvement after patients with schizophrenia were treated with CRT.

Methods

We recruited 79 patients with schizophrenia to complete 8 weeks of CRT and assessed their cognitive improvement outcomes. Eye movements were assessed by prosaccades, antisaccades, and free-viewing tasks at baseline, and neuropsychological tests in four cognitive domains were assessed before and after treatment to calculate treatment outcomes. Predictors of demographic information, clinical characteristics, and eye movement measures at baseline on cognitive improvement outcomes were analyzed using logistic regression analysis. We further compared the predictive performance between eye movement measurements and neuropsychological test regarding the effect of CRT on cognitive improvement, and explored factors that could be affect the treatment outcomes in different cognitive domains.

Results

As operationally defined, 33 patients showed improved in cognition (improved group) and 46 patients did not (non-improved group) after CRT. Patients with schizophrenia being employed, lower directional error rate in antisaccade task, and lower the gap effect (i.e., the difference in saccadic latency between the gap condition and overlap condition) in prosaccade task at baseline predicted cognitive improvement in CRT. However, performance in the free-viewing task not associated with cognitive improvement in patients in CRT. Our results show that eye-movement prediction model predicted the effect of CRT on cognitive improvement in patients with schizophrenia better than neuropsychological prediction model in CRT. In addition, baseline eye-movements, cognitive reserve, antipsychotic medication dose, anticholinergic cognitive burden change, and number of training sessions were associated with improvements in four cognitive domains.

Conclusion

Eye movements as a non-invasiveness, objective, and sensitive method of evaluating cognitive function, and combined saccadic measurements in pro- and anti-saccades tasks could be more beneficial than free-viewing task in predicting the effect of CRT on cognitive improvement in patients with schizophrenia.
Implementing a student-centered stroke intervention and prevention education program; evaluating motivation, cognitive load, and performance among middle school students
Authors: Imeh-Nathaniel Samuel , Iftikhar Irraj , Snell Ashley , Brown Katherine , Cooley Keiko , Black Asa , Khalil Mohammed K. , Nathaniel Thomas
Published: April 2024

Background

In this study, we investigated the association between motivation, cognitive load, difficulty, and performance in a stroke education outreach program implemented for middle school students.

Methods

Various interactive instructional activities were developed to engage students throughout the program to assess cognitive and intrinsic load arising from learner implementation of various tasks in a stroke education program for middle school kids. Performance was measured using a post-test to assess knowledge gained by the 6th, 7th, and 8th-grade middle school students. A short questionnaire was also administered to collect data on students’ motivation using the ARCS model to asses attention, relevance, confidence, and satisfaction. In addition, we evaluated difficulty level and cognitive load. The relationship between performance and motivation was assessed using Pearson’s correlation.

Results

In our results, there was no significant difference (p > 0.05) in performance between the 6th, 7th, and 8th-grade students. The difference in performance, cognitive load (mental effort and difficulty), or motivation between the 6th, 7th, and 8 t-grade students was not significant (p > 0.05). The correlation between motivation and performance was significant (r = 0.87, p = 0.001), while the correlation between mental effort and performance was not significant (r = 0.34, p = 0.270). Also, the correlation between difficulty and performance was not significant (r = 0.38, p = 0.361). In the ARCS motivation model, attention, and confidence received the lowest mean scores (3.9), while relevance received the highest score (4.3).

Conclusion

Our findings reveal the importance of implementing novel activities to enhance students’ motivation to improve performance in the implementation of stroke education outreach programs for middle school students.
Prevalence and associated factors of common mental disorders among internally displaced people by armed conflict in Cabo Delgado, Mozambique: a cross-sectional community-based study
Authors: Manafe Naisa , Ismael-Mulungo Hamida , Ponda Fábio , Dos Santos Palmira F. , Mandlate Flávio , Cumbe Vasco F. J. , Mocumbi Ana Olga , Oliveira Martins Maria R.
Published: April 2024

Background

Humanitarian emergencies are a major global health challenge with the potential to have a profound impact on people’s mental and psychological health. Displacement is a traumatic event that disrupts families and affects physical and psychological health at all ages. A person may endure or witness a traumatic incident, such as being exposed to war, and, as a result, develop post-traumatic stress disorder (PTSD). There is a lack of information about post-traumatic stress disorder, depression, and anxiety disorder in low and middle-income countries in humanitarian emergency contexts such as Mozambique. This study aimed to assess the prevalence of PTSD, depression, and anxiety, and associated factors among armed conflict survivors in Cabo Delgado, north region of Mozambique in 2023.

Methods

A community-based cross-sectional study was conducted between January and April 2023 among 750 participants, who were selected by convenience. A face-to-face interview used the Primary Care Post-Traumatic Stress Disorder Checklist (PC-PTSD-5) to evaluate PTSD, the Generalized Anxiety Disorder Scale (GAD-7) to evaluate anxiety and the Patient Health Questionnaire – Mozambique (PHQ-9 MZ) to evaluate depression. The association between PTSD and demographic and psychosocial characteristics was analyzed using bivariate and multivariable binary logistic regression. We used a 5% significance level.

Results

The three mental disorders assessed were highly prevalent in our sample with 74.3% PTSD, 63.8% depression, and 40.0% anxiety. The chance of developing PTSD was higher in females (AOR = 2.30, 95% CI 1.50–3.51), in patients with depression symptoms (AOR = 8.27, 95% CI = 4.97–13.74) and anxiety symptoms (AOR = 1.45, 95% CI = 0.84–2.50).

Conclusion

This study reported that the prevalence of PTSD, depression, and anxiety were high. Patients having depressive symptoms, anxiety symptoms, and being female are more at risk of developing PTSD. There is a need to integrate screening for common mental disorders in the context of humanitarian emergencies and its adapted integration of psychosocial interventions.
A data-driven approach for the partial reconstruction of individual human molar teeth using generative deep learning
Authors: Broll Alexander , Rosentritt Martin , Schlegl Thomas , Goldhacker Markus
Published: April 2024

Background and objective

Due to the high prevalence of dental caries, fixed dental restorations are regularly required to restore compromised teeth or replace missing teeth while retaining function and aesthetic appearance. The fabrication of dental restorations, however, remains challenging due to the complexity of the human masticatory system as well as the unique morphology of each individual dentition. Adaptation and reworking are frequently required during the insertion of fixed dental prostheses (FDPs), which increase cost and treatment time. This article proposes a data-driven approach for the partial reconstruction of occlusal surfaces based on a data set that comprises 92 3D mesh files of full dental crown restorations.

Methods

A Generative Adversarial Network (GAN) is considered for the given task in view of its ability to represent extensive data sets in an unsupervised manner with a wide variety of applications. Having demonstrated good capabilities in terms of image quality and training stability, StyleGAN-2 has been chosen as the main network for generating the occlusal surfaces. A 2D projection method is proposed in order to generate 2D representations of the provided 3D tooth data set for integration with the StyleGAN architecture. The reconstruction capabilities of the trained network are demonstrated by means of 4 common inlay types using a Bayesian Image Reconstruction method. This involves pre-processing the data in order to extract the necessary information of the tooth preparations required for the used method as well as the modification of the initial reconstruction loss.

Results

The reconstruction process yields satisfactory visual and quantitative results for all preparations with a root mean square error (RMSE) ranging from 0.02 mm to 0.18 mm. When compared against a clinical procedure for CAD inlay fabrication, the group of dentists preferred the GAN-based restorations for 3 of the total 4 inlay geometries.

Conclusions

This article shows the effectiveness of the StyleGAN architecture with a downstream optimization process for the reconstruction of 4 different inlay geometries. The independence of the reconstruction process and the initial training of the GAN enables the application of the method for arbitrary inlay geometries without time-consuming retraining of the GAN.
Revised contraindications for the use of non-medical WB-electromyostimulation. Evidence-based German consensus recommendations
Authors: von Stengel S. , Fröhlich M. , Ludwig O. , Eifler C. , Berger J. , Kleinöder H. , Micke F. , Wegener B. , Zinner C. , Mooren F. C. , Teschler M. , Filipovic A. , Müller S. , England K. , Vatter J. , Authenrieth S. , Kohl M. , Kemmler W.
Published: April 2024

Whole-body electromyostimulation has proven to be a highly effective alternative to conventional resistance-type exercise training. However, due to adverse effects in the past, very extensive contraindications have been put in place for the commercial, non-medical WB-EMS market. Considering recent positive innovations e.g., federal regulation, mandatory trainer education, revised guidelines, and new scientific studies on WB-EMS application, we believe that a careful revision of the very restrictive contraindications on WB-EMS is needed. This applies all the more because many cohorts with limited options for conventional exercise have so far been excluded. During a first meeting of an evidence-based consensus process, stakeholders from various backgrounds (e.g., research, education, application) set the priorities for revising the contraindications. We decided to focus on four categories of absolute contraindications: “Arteriosclerosis, arterial circulation disorders”, “Diabetes mellitus” (DM), “Tumor and cancer” (TC), “Neurologic diseases, neuronal disorders, epilepsy”. Based on scientific studies, quality criteria, safety aspects and benefit/risk assessment of the category, DM and TC were moved to the relative contraindication catalogue, while arteriosclerosis/arterial circulation disorders and neurologic diseases/neuronal disorders/epilepsy were still considered as absolute contraindications. While missing evidence suggests maintaining the status of neurologic diseases/neuronal disorders as an absolute contraindication, the risk/benefit-ratio does not support the application of WB-EMS in people with arteriosclerosis/arterial circulation diseases. Despite these very cautious modifications, countries with less restrictive structures for non-medical WB-EMS should consider our approach critically before implementing the present revisions. Considering further the largely increased amount of WB-EMS trials we advice regular updates of the present contraindication list.
Association between pathological characteristics and recurrence score by OncotypeDX in resected T1-3 and N0-1 breast cancer: a real-life experience of a North Hungarian regional center
Authors: Deme Dániel , Tamaskovics Bálint Ferenc , Jammoul Nizar , Kovács Sándor , Kayode Emmanuel Oladunjoye , Grice James W. , Telekes András
Published: April 2024

Introduction: The 21-gene analysis (OncotypeDX) is validated test for pT1-3, pN0-1 with hormone receptor (HR) positive and normal expression of human epidermal growth factor receptor-2 (HER2) breast cancer (BC) to determine the aggressiveness of the disease based on the calculation of Recurrence Score (RS).

Methods: In this retrospective study the authors correlated pathological characteristics and Recurrence Score (RS) by traditional statistical methods and Observed Oriented Modeling (OOM) in a realistic cohort of BC patients.

Results: OncotypeDX tests were performed in 94 tumour specimens of 90 BC patients. >83% of node-negative (pN0) and >72% of node-positive (pN1) cases could avoid chemotherapy. For pN0 cases, non-parametric correlation and tests demonstrated significant association in eight types of characteristics [progesterone receptor (PR) expression, Ki-67 value, Ki-67 group, PR group, grade, estrogen receptor (ER) expression, Nottingham Prognostic Index (NPI) and Clinical Risk]. For pN1 cases, parametric correlation and tests showed significant association in six characteristic types (number of positive nodes, ER and PR expression, PR group, Ki-67 group and NPI). Based on OOM for pN0 cases, significant associations were established in three characteristics (Ki-67 group, grade and NPI group). For pN1 cases OOM found significant associations in seven characteristics (PR group, PNI, LVI, Ki-67 group, grade, NPI group and number of positive nodes).

Conclusion: First in oncology, OOM was applied, which found some other significant characteristics associated with RS than traditional statistical methods. There were few patients, where no clinical associations were found between characteristics and RS contrary to statistically significant differences. Therefore, the results of these statistical analyses can be neither applied for individual cases nor able to provide the bases for screening patients, i.e., whether they need for OncotypeDX testing or not. OncotypeDX still provides a personalised approach in BC.
Spatial Heterogeneity in the Response of Winter Wheat Yield to Meteorological Dryness/Wetness Variations in Henan Province, China
Authors: Li Cheng , Gu Yuli , Xu Hui , Huang Jin , Liu Bo , Chun Kwok Pan , Octavianti Thanti
Published: April 2024

Knowledge of the responses of winter wheat yield to meteorological dryness/wetness variations is crucial for reducing yield losses in Henan province, China’s largest winter wheat production region, under the background of climate change. Data on climate, yield and atmospheric circulation indices were collected from 1987 to 2017, and monthly self-calibrating Palmer drought severity index (sc-PDSI) values were calculated during the winter wheat growing season. The main results were as follows: (1) Henan could be partitioned into four sub-regions, namely, western, central-western, central-northern and eastern regions, based on the evolution characteristics of the time series of winter wheat yield in 17 cities during the period of 1988–2017. Among them, winter wheat yield was high and stable in the central-northern and eastern regions, with a remarkable increasing trend (p < 0.05). (2) The sc-PDSI in February had significantly positive impacts on climate-driven winter wheat yield in the western and central-western regions (p < 0.05), while the sc-PDSI in December and the sc-PDSI in May had significantly negative impacts on climate-driven winter wheat yield in the central-northern and eastern regions, respectively (p < 0.05). (3) There were time-lag relationships between the sc-PDSI for a specific month and the atmospheric circulation indices in the four sub-regions. Furthermore, we constructed multifactorial models based on selected atmospheric circulation indices, and they had the ability to simulate the sc-PDSI for a specific month in the four sub-regions. These findings will provide scientific references for meteorological dryness/wetness monitoring and risk assessments of winter wheat production.
Strategic Ensilage of Signal Grass Pastures in Two Seasons in a Tropical Region
Authors: da Silveira Tâmara Chagas , Ribeiro Karina Guimarães , Roseira João Paulo Santos , Alves Wagner Sousa , Coutinho Danielle Nascimento , dos Anjos Albert José , Pereira Odilon Gomes
Published: April 2024

In tropical regions, grass silage can be produced from the pasture in the rainy season to feed animals during the dry season. We evaluated the chemical composition and fermentation characteristics of ensiled signal grass (Urochloa decumbens Stapf. Basilisk) fertilized with nitrogen (N) or intercropped with calopo (Calopogonium mucunoides Desv.) with and without microbial inoculant. We used a 4 × 2 factorial scheme in a randomized block design, with two blocks and two treatments per block, considering p > 0.05. We studied signal grass fertilized with 0 kg ha−1 of N (0 N), 50 kg ha−1 of N (50 N), or 100 kg ha−1 of N (100 N), or intercropped with calopo legume (LEG), with (I) or without (WI) inoculant, in two seasons. During the dry–water transition, lower concentrations of butyric acid were observed in 50 N and LEG silages (2.77 and 2.55 g kg−1 dry matter, DM) (inoculated) compared to control (7.77 g kg−1 DM). During the water–dry transition, higher concentrations of crude protein were observed in 100 N and LEG silages (71.90 and 54.6 g kg−1 DM) than in 0 N (46.3 g kg−1 DM). The signal grass–calopo intercropping is an alternative to nitrogen fertilization, as it provides forage with a higher protein content and silage with satisfactory fermentative characteristics.
Interconnected Markets: Unveiling Volatility Spillovers in Commodities and Energy Markets through BEKK-GARCH Modelling
Authors: Paientko Tetiana , Amakude Stanley
Published: April 2024

Food commodities and energy bills have experienced rapid undulating movements and hikes globally in recent times. This spurred this study to examine the possibility that the shocks that arise from fluctuations of one market spill over to the other and to determine how time-varying the spillovers were across a time. Data were daily frequency (prices of grains and energy products) from 1 July 2019 to 31 December 2022, as quoted in markets. The choice of the period was to capture the COVID pandemic and the Russian–Ukrainian war as events that could impact volatility. The returns were duly calculated using spreadsheets and subjected to ADF stationarity, co-integration, and the full BEKK-GARCH estimation. The results revealed a prolonged association between returns in the energy markets and food commodity market returns. Both markets were found to have volatility persistence individually, and time-varying bidirectional transmission of volatility across the markets was found. No lagged-effects spillover was found from one market to the other. The findings confirm that shocks that emanate from fluctuations in energy markets are impactful on the volatility of prices in food commodity markets and vice versa, but this impact occurs immediately after the shocks arise or on the same day such variation occurs.
Bounding Volume Hierarchy-Assisted Fast SAR Image Simulation Based on Spatial Segmentation
Authors: Wu Ke , Jin Guowang , Xiong Xin , Shi Quanjie
Published: April 2024

In order to improve the simulation efficiency under the premise of ensuring the fidelity of synthetic aperture radar (SAR) simulation images, we propose a BVH-assisted fast SAR image simulation method based on spatial segmentation. The beam scanning model is established based on RD imaging geometric relation, and the bounding volume hierarchy (BVH) algorithm is used to assist in obtaining the time-varying latticed radiation and shadow areas within the radar beam, combining them with the real-time position of the sensors to complete the simulation of the electromagnetic (EM) wave transmission. The ray tracing algorithm is used to calculate the multiple backscatter fields of EM waves, including various material properties of the target surface. The SAR spatial traversal is adopted to spatially segment the latticed radiation area, and the compute unified device architecture (CUDA) kernel function is designed using the echo matrix cell method to make each cell of the target echo matrix as a subfield of the backscattering field, and the position of the echo matrix cell is traversed to obtain the target backscattering field. The target simulated echo is processed by the range Doppler (RD) imaging algorithm to obtain the SAR-simulated image. The simulation results show that compared with a CPU single-thread simulation, the simulation speed of the proposed method is significantly improved, and the SAR simulation image has high structural similarity with the real image, which fully verifies the effectiveness of the proposed method.
A Lightweight File System Design for Unikernel
Authors: Cho Kyungwoon , Bahn Hyokyung
Published: April 2024

Unikernels are specialized operating system (OS) kernels optimized for a single application or service, offering advantages such as rapid boot times, high performance, minimal memory usage, and enhanced security compared to general-purpose OS kernels. Unikernel applications must remain compatible with the runtime environment of general-purpose kernels, either through binary or source compatibility. As a result, many Unikernel projects have prioritized system call compatibility over performance enhancements. In this paper, we explore the design principles of Unikernel file systems and introduce a new file system tailored for Unikernels named ULFS (Ultra Lightweight File System). ULFS provides system call services akin to those of general-purpose OS kernels but achieves superior performance and security with significantly fewer system resources. Specifically, ULFS is developed as a lightweight file system embracing Unikernel design principles. It streamlines system calls, removes unnecessary locks, and omits permission checks for multiple users, utilizing a non-hypervisor architecture. This approach significantly reduces the memory footprint of the file system and enhances performance. Through measurement studies, we assess the performance and memory requirements of various file systems from major Unikernel projects. Our findings demonstrate that ULFS surpasses several existing Unikernel file systems, including Rumpvfs, Ramfs-u, Ramfs-q, 9pfs, and Hcfs.
Seatbelt Detection Algorithm Improved with Lightweight Approach and Attention Mechanism
Authors: Qiu Liankui , Rao Jiankun , Zhao Xiangzhe
Published: April 2024

Precise and rapid detection of seatbelts is an essential research field for intelligent traffic management. In order to improve the detection precision of seatbelts and speed up algorithm inference velocity, a lightweight seatbelt detection algorithm is proposed. Firstly, by adding the G-ELAN module designed in this paper to the YOLOv7-tiny network, the optimization of construction and reduction of parameters are accomplished, and the ResNet is compressed with the channel pruning approach to decrease computational overheads. Then, the Mish activation function is utilized to replace the Leaky Relu in the neck to enhance the non-linear competence of the network. Finally, the triplet attention module is integrated into the model after pruning to make up for the underlying performance reduction caused by the previous stage and upgrade overall detection precision. The experimental results based on the self-built seatbelt dataset showed that, compared to the initial network, the Mean Average Precision (mAP) achieved by the proposed GM-YOLOv7 was improved by 3.8%, while the volume and the computation amount were lowered by 20% and 24.6%, respectively. Compared with YOLOv3, YOLOX, and YOLOv5, the mAP of GM-YOLOv7 increased by 22.4%, 4.6%, and 4.2%, respectively, and the number of computational operations decreased by 25%, 63%, and 38%, respectively. In addition, the accuracy of the improved RST-Net increased to 98.25%, while the parameter value was reduced by 48% compared to the basic model, effectively improving the detection performance and realizing a lightweight structure.
Smart City Actions Integrated into Urban Planning: Management of Urban Environments by Thematic Areas
Authors: Jacques Elizeu de Albuquerque , Júnior Alvaro Neuenfeldt , de Paris Sabine , Francescatto Matheus Binotto , Nunes Raquel Francieli Bilhalva
Published: April 2024

Over the years, the imbalance between population needs and urban spaces’ organized development has been accentuated by increasing urbanization. The implementation of smart city actions began in the 1990s, with the development of integrated solutions in cities, harmonizing social, environmental, and economic aspects. This research measures the impact of thematic areas on smart cities’ management performance. The multi-criteria Decision Making Trial and Evaluation Laboratory (DEMATEL) method was used to identify the interdependent relations between smart cities’ thematic areas, structuring a diagram of cause-and-effect relations using threshold quantification values. Considering their degree of importance in smart city management, the thematic areas of technology and innovation, living environment and infrastructure, education and training, and governance and engagement are highlighted. For the degree of influence, the most influential thematic areas are coexistence and reciprocity, living environment and infrastructure, entrepreneurship, and healthcare. Also, the cause-and-effect analysis identified governance and engagement, education and training, and mobility as central thematic areas for smart city management. Finally, the research construct was developed by ranking the thematic areas’ performance in urban space planning.
Mid- and High-Latitude Electron Temperature Dependence on Solar Activity in the Topside Ionosphere through the Swarm B Satellite Observations and the International Reference Ionosphere Model
Authors: Pignalberi Alessio , Truhlik Vladimir , Giannattasio Fabio , Coco Igino , Pezzopane Michael
Published: April 2024

This study focuses on the open question of the electron temperature (Te) variation with solar activity in the topside ionosphere at mid- and high latitudes. It takes advantage of in situ observations taken over a decade (2014–2023) from Langmuir probes on board the low-Earth-orbit Swarm B satellite and spanning an altitude range of 500–530 km. The study also includes a comparison with Te values modeled using the International Reference Ionosphere (IRI) model and with Millstone Hill (42.6° N. 71.5° W) incoherent scatter radar observations. The largest Te variation with solar activity was found at high latitudes in the winter season, where Te shows a marked decreasing trend with solar activity in the polar cusp and auroral regions and, more importantly, at sub-auroral latitudes in the nightside sector. Differently, in the summer season, Te increases with solar activity in the polar cusp and auroral regions, while for equinoxes, variations are smaller and less clear. Mid-latitudes generally show negligible Te variations with solar activity, which are mostly within the natural dispersion of Te observations. The comparison between measured and modeled values highlighted that future implementations of the IRI model would benefit from an improved description of the Te dependence on solar activity, especially at high latitudes.
First Observations of Buzzards (Buteo) as Definitive Hosts of Sarcocystis Parasites Forming Cysts in the Brain Tissues of Rodents in Lithuania
Authors: Prakas Petras , Jasiulionis Marius , Šukytė Tautvilė , Juozaitytė-Ngugu Evelina , Stirkė Vitalijus , Balčiauskas Linas , Butkauskas Dalius
Published: April 2024

Representatives of the genus Sarcocystis are worldwide distributed apicomplexan parasites characterised by two-host prey-predator relationships. Sarcocystis spp. produce sarcocysts in the muscles and brains of intermediate hosts and develop sporocysts in the intestines of definitive hosts. Two species, Sarcocystis glareoli and Sarcocystis microti, previously assigned to the genus Frenkelia, form cysts in the brains of rodents and are transmitted through the common buzzard (Buteo buteo). In our study, brain samples of 694 small mammals caught in different regions of Lithuania were examined for Sarcocystis spp. Additionally, 10 B. buteo and two rough-legged buzzards (Buteo lagopus) were tested for sporocysts of the analysed parasites. Sarcocystis species were identified based on 28S rRNA sequence comparison. Of the eleven species of small mammals tested, Sarcocystis parasites were observed only in the bank vole (Clethrionomys glareolus). Cysts of S. glareoli were detected in 34 out of 374 C. glareolus (9.1%, 95% CI = 6.4–12.5%). Molecular investigation showed the presence of only S. glareoli in the intestines of 50% of B. buteo. Furthermore, two species, Sarcocystis sp. Rod3 and Sarcocystis sp. Rod4, were confirmed in B. lagopus. Our results demonstrate the need for further studies on Sarcocystis cycling between rodents and birds.
Implementing A Flexible Sensor to Identify Forces during Instrument-Assisted Soft Tissue Mobilization
Authors: Martonick Nickolai J. P. , Baker Russell T. , McGowan Craig P.
Published: April 2024

Instrument-assisted soft tissue mobilization (IASTM) techniques use specialized hand-held instruments for applying controlled mechanical forces to the body with the goal of facilitating healing, improving range of motion, and reducing pain. Nevertheless, an optimal range of forces for achieving clinical outcomes has yet to be established. A barrier to advancing research on IASTM force optimization is the lack of commercially available instruments that quantify treatment forces. The aim of the current study was to assess the feasibility of attaching a flexible force sensor to a commercially available IASTM instrument to obtain valid force measurements. The validity of this novel approach was assessed by comparing data between the flexible force sensor and a force plate during a simulated treatment. Intraclass correlation coefficients, linear regression models, and Bland Altman plots all indicated excellent agreement between the force plate and flexible sensor when the instrument was used at 45°, 65°, and 90° treatment angles. Agreement between measures decreased when the instrument was held at 30°. Thus, commercially available instruments with attached sensors could make force measurement more accessible and feasible for a wider range of research settings, facilitating the advancement of IASTM research and ultimately informing clinical decision-making to improve patient care.
Remote Wearable Neuroimaging Devices for Health Monitoring and Neurophenotyping: A Scoping Review
Authors: Emish Mohamed , Young Sean D.
Published: April 2024

Digital health tracking is a source of valuable insights for public health research and consumer health technology. The brain is the most complex organ, containing information about psychophysical and physiological biomarkers that correlate with health. Specifically, recent developments in electroencephalogram (EEG), functional near-infra-red spectroscopy (fNIRS), and photoplethysmography (PPG) technologies have allowed the development of devices that can remotely monitor changes in brain activity. The inclusion criteria for the papers in this review encompassed studies on self-applied, remote, non-invasive neuroimaging techniques (EEG, fNIRS, or PPG) within healthcare applications. A total of 23 papers were reviewed, comprising 17 on using EEGs for remote monitoring and 6 on neurofeedback interventions, while no papers were found related to fNIRS and PPG. This review reveals that previous studies have leveraged mobile EEG devices for remote monitoring across the mental health, neurological, and sleep domains, as well as for delivering neurofeedback interventions. With headsets and ear-EEG devices being the most common, studies found mobile devices feasible for implementation in study protocols while providing reliable signal quality. Moderate to substantial agreement overall between remote and clinical-grade EEGs was found using statistical tests. The results highlight the promise of portable brain-imaging devices with regard to continuously evaluating patients in natural settings, though further validation and usability enhancements are needed as this technology develops.
AI and Aphasia in the Digital Age: A Critical Review
Authors: Privitera Adam John , Ng Siew Hiang Sally , Kong Anthony Pak-Hin , Weekes Brendan Stuart
Published: April 2024

Aphasiology has a long and rich tradition of contributing to understanding how culture, language, and social environment contribute to brain development and function. Recent breakthroughs in AI can transform the role of aphasiology in the digital age by leveraging speech data in all languages to model how damage to specific brain regions impacts linguistic universals such as grammar. These tools, including generative AI (ChatGPT) and natural language processing (NLP) models, could also inform practitioners working with clinical populations in the assessment and treatment of aphasia using AI-based interventions such as personalized therapy and adaptive platforms. Although these possibilities have generated enthusiasm in aphasiology, a rigorous interrogation of their limitations is necessary before AI is integrated into practice. We explain the history and first principles of reciprocity between AI and aphasiology, highlighting how lesioning neural networks opened the black box of cognitive neurolinguistic processing. We then argue that when more data from aphasia across languages become digitized and available online, deep learning will reveal hitherto unreported patterns of language processing of theoretical interest for aphasiologists. We also anticipate some problems using AI, including language biases, cultural, ethical, and scientific limitations, a misrepresentation of marginalized languages, and a lack of rigorous validation of tools. However, as these challenges are met with better governance, AI could have an equitable impact.
Exploring Embodied and Bioenergetic Approaches in Trauma Therapy: Observing Somatic Experience and Olfactory Memory
Authors: Invitto Sara , Moselli Patrizia
Published: April 2024

Recent studies highlight how body psychotherapy is becoming highly cited, especially in connection with studies on trauma-related disorders. This review highlights the theoretical assumptions and recent points in common with embodied simulation and new sensory theories by integrating bioenergetic analysis, embodiment, and olfactory memory in trauma and post-traumatic stress disorder (PTSD) therapy. Embodied memory, rooted in sensorimotor experiences, shapes cognitive functions and emotional responses. Trauma, embodied in somatic experiences, disrupts these processes, leading to symptoms such as chronic pain and dissociation. The literature discussed highlights the impact of burning odors on individuals with PTSD and those who have experienced childhood maltreatment. Burning odors can increase stress and heart rate in war veterans, with sensitivity to these odors intensifying over time since the trauma. Additionally, adults who experienced childhood maltreatment exhibit faster processing of unpleasant odors and increased symptom severity. Grounding techniques, such as adopting a balanced posture, enhance breathing and sensory capabilities, potentially aiding in managing symptoms associated with trauma-related disorders such as PTSD.
An Overview of the Bodily Awareness Representation and Interoception: Insights and Progress in the Field of Neurorehabilitation Research
Authors: Parma Chiara , Doria Federica , Zulueta Aida , Lanzone Jacopo , Boscarino Marilisa , Giani Luca , Lunetta Christian , Vassallo Marta , Parati Eugenio Agostino , Picozzi Mario , Sattin Davide
Published: April 2024

In the last two decades, the scientific literature on so-called body representations has been increasing, and the notion of body awareness (BA) is particularly interesting for neurorehabilitation. In this article, we present results derived from recent studies on this representation, considering the different definitions and explicative models proposed as well as the empirical settings used to test it, providing an extensive overview of these issues. This article discusses the challenge of understanding how we integrate the sensory experiences of proprioception (knowing where our body is in space) and interoception (sensing internal bodily sensations, like hunger of thirst) with our perception of self. This is a difficult problem to analyze because our awareness of our body is inherently linked to our perspective, since the body is the means through which we interact with the world. Presenting the different viewpoints offered by recent theories on this concern, we highlighted that the neurorehabilitation and psychiatric settings offer two important fields useful for the study of BA because in them it is possible to analyze bodily representations by inducing/observing a controlled discrepancy between dysfunctional content and sensory inputs.
Outcome of Tocilizumab Treatment in Febrile Neutropenic Children with Severe Sepsis/Septic Shock in a Single-Center Retrospective Case Series
Authors: Chen Shih-Hsiang , Chang Tsung-Yen , Wang Yi-Lun , Lee En-Pei , Lin Jainn-Jim , Hsiao Yi-Wen , Jaing Tang-Her , Yang Chao-Ping , Hung Iou-Jih
Published: April 2024

Purpose: To assess the efficacy of an IL-6 blockade with tocilizumab on treatment outcome of severe sepsis/septic shock in children with febrile neutropenia. Methods: We performed a retrospective study of febrile neutropenic patients younger than 18 years old who developed severe sepsis/septic shock at a single medical center between November 2022 and October 2023. Results: Seven patients with febrile neutropenia complicated with severe sepsis/septic shock were identified. Four of seven patients received tocilizumab in addition to standard of care. The median IL-6 level before administration of tocilizumab was 14,147 pg/mL (range: 672–30,509 pg/mL). All four patients successfully recovered from severe sepsis/septic shock. Three of seven patients received standard of care without tocilizumab. IL-6 levels were checked intwo2 patients, with a median of 1514.5 (range: 838–2191). Only one of three (33%) patients without tocilizumab therapy made a full recovery from severe sepsis/septic shock. The mortality rate was higher in patients without tocilizumab therapy compared to patients with tocilizumab therapy (67% vs. 0%). Conclusions: Administration of tocilizumab reduced mortality of severe sepsis/septic shock in children with febrile neutropenia. However, it warrants confirmation with a larger number of patients and a longer follow-up.