bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS TINGKAT KESEHATAN BANK PAPUA MENGGUNAKAN METODE RBBR (RISK BASED BANK RATING) PERIODE TAHUN 2011-2018
Authors: Inayah Eka Putri , Wahib Moh , Pratiwi Ira Eka
Published: October 2021

Penelitian ini bertujuan untuk menganalisis tingkat kesehatan Bank Papua periode tahun 2011-2018 menggunakan metode RBBR (Risk Based Bank Rating). Dalam penelitian ini dilakukan penilaian terhadap tiga faktor RBBR, yaitu faktor Risk Profile melalui rasio NPL dan LDR, faktor rentabilitas melalui rasio ROA dan NIM dan faktor permodalan melalui rasio CAR. Jenis penelitian ini adalah deskriptif  dengan pendekatan kuantitatif. Rumusan masalah ada dua, yaitu, pertama mengenai analisis tingkat kesehatan Bank Papua menggunakan metode RBBR (Risk Based Bank Rating) dan yang kedua menyangkut performa Bank papua dilihat dari indikator NPL, LDR, ROA, NIM dan CAR.

Hasil penelitian ini menunjukkan berdasarkan analisis tingkat kesehatan Bank Papua menggunakan metode Risk Based Bank Rating (RBBR) melalui rasio NPL, LDR, ROA, NIM dan CAR maka kondisi tingkat kesehatan Bank Papua yaitu dapat dikategorikan berada pada predikat Sehat. Namun demikian, perkembangan nilai-nilai rasio pada Bank Papua periode 2011-2018 setiap tahunnya bergerak secara fluktuatif yang berarti perkembangannya naik turun dan pada tahun-tahun tertentu bisa mencapai angka yang kurang baik atau melebihi batas minimum nilai dari masing-masing rasio. Lalu kemudian berdasarkan indikator NPL, LDR, ROA, NIM dan CAR performa Bank Papua dikategorikan baik. Kesimpulan dari hasil penelitian ini berdasarkan analisis tingkat kesehatan Bank Papua menggunakan metode Risk Based Bank Rating (RBBR) melalui rasio NPL, LDR, ROA, NIM dan CAR maka kondisi tingkat kesehatan Bank Papua yaitu dapat dikategorikan berada pada predikat Sehat. Kemudian berdasarkan indikator NPL, LDR, ROA, NIM dan CAR maka dapat disimpulkan bahwa performa Bank Papua dikategorikan baik.
La medicina experimental en la Argentina durante la primera mitad del siglo XX
Authors: Buschini José , Zabala Juan Pablo
Published: October 2021

Este trabajo toma como objeto el proceso de conformación y desarrollo de un entramado institucional estatal y universitario destinado a la realización de investigaciones en medicina experimental emplazado en Argentina durante la primera mitad del siglo XX. Para el análisis se adopta una estrategia teórico-metodológica que consiste en reconstruir las trayectorias estudiantiles y laborales de tres actores que tuvieron un papel clave en este proceso: Ángel Roffo, Salvador Mazza y Bernardo Houssay. Las preguntas que guían esta reconstrucción apuntan a entender cómo se conformaron en estos sujetos vocaciones científicas y el modo en que lograron transformarlas en carreras laborales efectivas en un contexto social en el que no existía un rol social definido para la ciencia.
Os donos do solo
Authors: Silva Rodrigo Machado da
Published: October 2021

O documento transcrito e aqui apresentado, ainda inédito e não catalogado, refere-se a um parecer encomendado pela Câmara Municipal de Ouro Preto, em 1898, ao advogado e historiador Diogo Luiz de Almeida Pereira de Vasconcellos (1843-1927). O parecer é um estudo efetuado por Vasconcellos em que faz uma avaliação do direito legal e histórico da Câmara em deter a propriedade das datas mineratórias de ouro que se encontravam dentro das Sesmarias Municipais, a fim de conceder direitos de exploração ao engenheiro Alcides Medrado. A documentação trabalhada encontra-se no Arquivo Público Municipal de Ouro Preto.
From Community Autonomy in Hungary to Indigenous Self-Determination in the Outback of Australia: Can Non-Territorial Autonomy Find Traction Down Under?
Authors: de Villiers Bertus
Published: October 2021

Hungary has, during the past three decades, developed what could arguably be described as one of the most advanced institutional systems of non-territorial autonomy in the world. Being so advanced does not of course mean the system is perfect or beyond criticism. But it does provide potentially useful insights into how non-territorial autonomy can or cannot work in practice. This article reflects on the institutional design of Hungary and asks whether principles can be identified that may be employed by indigenous groups in Australia and beyond in their search for a form of self-government. The theory and practice of non-territorial autonomy has so far been the focus of experts predominately from Central and Eastern Europe and the Russian Federation. This article considers whether any insight can be gained to apply the principles of non-territorial autonomy to other jurisdictions. The institutional design in place in Hungary may offer useful insight into how indigenous communities, particular some Aboriginal communities in Australia, may be bestowed with legal powers as a community to make decisions of a cultural and linguistic nature and to cooperate via the legal entity with local and state authorities. The United Nations Declaration on the Rights of Indigenous Peoples refers to selfdetermination and autonomy without placing those terms into a specific set of institutional arrangements. Whereas non-territorial autonomy may not be suitable for all communities, this article contends that non-territorial arrangements may offer an opportunity for self-government to indigenous (and other) communities that share a strong sense of identity; that do not have a geographical base where they constitute the majority; and where a communal desire for a form of self-government in public law exists.
Antibiotic susceptibility pattern of Escherichia coli isolated from food, cooking utensils and palms of food handlers in some restaurants in Zaria, Nigeria
Authors: Etalong Victoria , Tytler Babajide A. , Profit Igba , Gbonjubola Adeshina O.
Published: October 2021

Foodborne disease is a major public health problem causing considerable morbidity and mortality annually. In the present study, the antibiotic susceptibility patterns of Escherichia coli isolated from food, cooking utensils and palms of food handlers in some restaurants in Zaria, Nigeria were evaluated. A total of 250 samples (220 food samples, 7 hand samples of food handlers, 10 plate samples within restaurants and 13 spoon samples) were collected from five locations in Zaria, Nigeria and analysed for microbial contaminations using standard microbiological techniques. The antibiotic susceptibility pattern of the isolates was determined using Kirby-Bauer modified disc agar diffusion technique. Results revealed that out of 158 acclaimed Enterobacteriaceae isolates evaluated, 19 % (30) were confirmed to be E. coli, while 81 % were Klebsiella. spp, Citrobacter fruendii, Enterobacter spp, Shigella spp, Salmonella spp, Serratia spp, and Cronobacter sakazaki. The majority of the isolates were resistant to amoxiclav (26.08%), ampicillin (26.08%), tetracycline (26.08%) and metronidazole (13.04%). A 33.3% of the isolates were multidrug-resistant. The E. coli isolates were mostly multiple antibiotic resistance with 43.3% having multiple antibiotic resistance index (MARI) ≥ 0.2. In conclusion, E. coli evolved resistance to ampicillin, Amoxicillin Clavulanic acid, and Tetracycline and other tested antimicrobial drugs which would make the treatment of Escherichia coli infections difficult
ANTI-INFLAMMATORY AGENTS FROM PLANTS
Authors:   Lala Lajpat Rai College of Pharmacy, Moga-142 001, Punjab, India., Lehra K. S. , Goyal S , Bajwa B. S , Kaur R , Singh S.
Published: October 2021

Most of the available non-steroidal anti-inflammatory drugs are devoid of gastro protective property.Therefore, the search for new anti-inflammatory agents from the huge array of medicinal plant resources is intensifying. Guggul sterones, boswellic acid, curcumin, withaferin-A and and rographolide have been reported to be promising anti-inflammatory agents in animal models. Scientists are of the view that there is acute shortage of leads for developing anti-inflammatory drugs. We need to initiate pending work on these phyto-constituents with emphasis on side effect profile. This paper provides an overview on the recent findings of some plants having anti-inflammatory activity and chemical constituents isolated from them.
Effect of Music Intervention on Anxiety in Patients Undergoing Periodontal Surgery: A Pilot Study
Authors: Burana Thitiwan Teparat
Published: October 2021

Objective: The effect of music listening on blood pressure (BP), heart rate (HR) and anxiety level (AL) was investigated for thirty patients undergoing periodontal surgery. Methods: A total of sixty patients referred for periodontal surgery were randomized into two equal groups as i) without music (control), and ii) with music (test). Before and after the procedure, BP and HR were recorded. All patients responded to AL assessment using facial image scale (FIS) before and after surgery. After listening to music before and during the procedure BP, HR and AL were assessed for the test group. Results: Systolic BP (SBP) in both groups increased but showed no statistically significant difference between the two groups (p>0.05). Diastolic BP (DBP) increased after treatment with no statistically significant difference (p>0.05) between test (4.70 mmHg) and control (6.20 mmHg) groups. HR decreased after the procedure in both test and control groups (8.40 vs. 9.03 beats per minute) with no statistically significant difference between the two groups (p>0.05).AL after the procedure decreased in both groups but with no statistically significant difference (p>0.05). Conclusion: Only HR and AL decreased after music intervention.However, no differences in BP, HR and AL were found between groups with and without music. This clinical trial was registered with TCTR (Thai Clinical Trials Registry) code TCTR20190411004.
Cervicofacial Necrotizing Fasciitis and Candida spp
Authors: Giselle Juárez-Rebollar Alejandra
Published: October 2021

Cervicofacial necrotizing fasciitis is a rapidly evolving bacterial infection, which can be associated with multiple complications and poor health. However, there are few reported cases that are associated with Candida species, and the studies that report this indicate that it is found mainly in areas such as the pelvis, thorax and to a lesser degree in the arms and legs. The presence of Necrotizing Fasciitis in the cervicofacial region is very rare, which makes the present study relevant. Material and Method: Descriptive, observational and retrospective study of Odontogenic Cervicofacial Necrotizing Fasciitis and the presence of Candida spp., Carried out during one year, in the Maxillofacial Surgery service of the Specialty Hospital, of the National Medical Center "La Raza" (IMSS). Patients older than 18 years, who were diagnosed with Necrotizing Cervicofacial Fasciitis of dental origin, were included in the study, reporting the presence of Candida. Treatment consisted of debridement of necrotic tissue, culture, dressings, intravenous antibiotics, and secondary surgical scrubs. Results: In one year, 7 cases of Cervicofacial Necrotizing Fasciitis of dental origin were obtained, of which 3 patients had associated Candida species, the rest of the cultures were reported polymicrobial. The most associated comorbidities were uncontrolled diabetes mellitus and arterial hypertension, there was a predilection for the male sex, the median age was 63 years, the ranges (min: 24 and max: 83). In addition, it was found that the 3 patients who presented candida species in their cultures were overweight and their evolution was torpid. Conclusion: It is important to perform cultures and biopsies to report the microbial species found in pathologies such as Necrotizing Fasciitis and to be able to provide better treatment specifically to the patient. Candida species do not usually appear associated with Necrotizing Fasciitis, which is why when other non-bacterial species are present, patients must undergo specific and individualized treatment to treat bacterial infections (necrotizing fasciitis) and in this case also the fungal (candida), remembering that the two act synergistically.
Industry 4.0 and the Future of Reservoir Exploration and Characterization
Authors: Oliveira LA Blanes de
Published: October 2021

The oil and gas sector seeks to adapt to changes in industry 4.0. Advances in computational processing and artificial intelligence have allowed machines to perform increasingly complex activities. However, the application of these advances to the activities of the oil industry still involves much speculation. While some areas show clear gains with the implementation of machine learning, the exploration and characterization of reservoirs still represent a challenge concerning this topic. As the primary information acquired in reservoirs, such as rock and fluid samples, well logs, and seismic data, presents a wide range of scales, the real gain from machine learning techniques would likely be integrating different databases in different scales. Such integration would improve geological and production models. The spread of information in these databases would also have the potential to decrease exploratory success. The joint efforts of oil and gas companies and research and education institutions will be essential to increase the oil and gas industry.
Comparative Analysis of the Effect of Barite and Hematite on the Rheology of Water-Based Drilling Mud
Authors: H Osei
Published: October 2021

High demand for oil and gas has led to exploration of more petroleum resources even at remote areas. The petroleum resources are found in deeper subsurface formations and drilling into such formations requires a well-designed drilling mud with suitable rheological properties in order to avoid or reduce associated drilling problems. This is because rheological properties of drilling muds have considerable effect on the drilling operation and cleaning of the wellbore. Mud engineers therefore use mud additives to influence the properties and functions of the drilling fluid to obtain the desired drilling mud properties especially rheological properties. This study investigated and compared the impact of barite and hematite as weighting agents for water-based drilling muds and their influence on the rheology. Water-based muds of different concentrations of weighting agents (5%, 10%, 15% and 20% of the total weight of the drilling mud) were prepared and their rheological properties determined at an ambient temperature of 24ᵒC to check their impact on drilling operation. The results found hematite to produce higher mud density, plastic viscosity, gel strength and yield point when compared to barite at the same weighting concentrations. The higher performance of the hematite-based muds might be attributed to it having higher specific gravity, better particle distribution and lower particle attrition rate and more importantly being free from contaminants. The water-based muds with hematite will therefore be more promising drilling muds with higher drilling and hole cleaning efficiency than those having barite.
Treatment outcomes and influencing factors on patients with Pulmonary Tuberculosis: a retrospective study
Authors:   Infectious Diseases Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran, Ayatollahi Jamshid , Halvani Abolhasan ,   Department of Internal Medicine, School of Medicine, Yazd Medical Science Branch, Islamic Azad University, Yazd, Iran, Khezri Mohammadhesam Gharaei ,   School of Medicine, Yazd Medical Science Branch, Islamic Azad University, Yazd, Iran, Shahcheraghi Hossein ,   Infectious Diseases Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Published: October 2021

Introduction: Tuberculosis infection caused by Mycobacterium tuberculosis is one of the most common infectious diseases, especially in countries such as Iran. The course of treatment and the number of drugs used vary depending on the severity of the disease and the parts of the body involved. The resistant tuberculosis to treatment has increased in recent years. Thus, this study was conducted to investigate the frequency distribution of response to treatment of patients with tuberculosis in Sirjan, Iran. Methods: This descriptive cross-sectional study investigated all patients with tuberculosis in Sirjan city who had referred to health centers during the years 2011-2019. The data collection tool was a pre-prepared checklist that included information on age, sex, sputum smear results, sputum culture results, diabetes, patients' nationality, drug side effects, and response to treatment. Finally, data was entered into SPSS version 22, and analyzed. Results: In this study, the overall response rate was 83% and the mortality rate was 10%. Between the frequency distribution of response to treatment in terms of gender, age, sputum smear results, sputum culture results, patients' nationality and diabetes was not statistically significant difference. Also, no statistically significant difference was found between the frequency distribution of pulmonary TB treatment response in terms of drug allergy, drug hepatitis and other drug side effects. Conclusion: According to results, can be concluded that none of the variables: age, sex, smear and culture result, and history of diabetes have no an effect on response to treatment and mortality of tuberculosis.
The role of bacterial colonization of ventilator circuit in development of ventilator associated pneumonia in ICU of Medical Center Hospital in Tripoli, Libya
Authors:   Department of Medical Laboratories Sciences, Faculty of Medical Technology, The University of Tripoli, Libya, Elkammoshi Asma , Ben Ashur Abir ,   Department of Medical Laboratories Sciences, Faculty of Medical Technology, The University of Tripoli, Libya, El Magrahi Hamida ,   Department of Medical Laboratories Sciences, Faculty of Medical Technology, The University of Tripoli, Libya, Abdulatif Aya ,   Department of Medical Laboratories Sciences, Faculty of Medical Technology, The University of Tripoli, Libya, Almarouq Malak ,   Department of Medical Laboratories Sciences, Faculty of Medical Technology, The University of Tripoli, Libya
Published: October 2021

Introduction: In mechanically ventilated patients, ventilator-associated pneumonia (VAP) is a major cause of prolonged hospitalization with increased morbidity and mortality. There is a lack of studies on the relationship between bacterial colonization of the ventilator circuit (VC) and VAP. This study aimed to investigate the role of bacterial colonization of VC in the development of VAP and identify antibiotic susceptibility trends for isolated strains. Methods: A prospective study of the bacterial culture has been performed between February 2021 to March 2021 on a total of 100 mechanically ventilated patients, (n =50) samples have been obtained from patient's lower respiratory tract (LRT) and (n =50) were taken from mechanical ventilator equipment VC. Paired samples of bacteria isolated from VC and LRT, where VC was colonized before LRT. Results: A total of 58 samples were cultured positively, while 42 specimens showed negative bacterial growth. However, there was no substantial difference in comparing between the bacterial colonization of the ventilator system and the patient samples. Most isolated organisms were gram-negative bacteria which were found in the ventilator circuit with 26 (68.4%), and 14 (70%) in patient’s LRT. Gram-positive was detected in 12 (31.6%) and 6 (30%) of the ventilator circuit, and patient's LRT, respectively. The predominant bacterial type was Acinetobacter baumannii organism at the VC with 10 (26.3%) and LRT at 4 (20%) followed by Klebsiella pneumoniae (8 (21.1%) in VC and 4 (20%) in LRT). Moreover, A. baumannii showed a full resistance to amoxicillin and the first generation of cephalosporins, while the other bacterial types were resistant to the most antibiotics used in this research. Conclusions: Bacterial colonization of ventilator circuit VC is a significant cause of VAP development in mechanically ventilated patients. Preventive strategies for the early detection and decontamination of contaminated VC can play a crucial role in ventilator-associated pneumonia prevention.
Candida species oral detection and infection in patients with diabetes mellitus: a meta-analysis
Authors:   Department of Stomatology, Oral Medicine Unit. Faculty of Dentistry, University of Granada, Granada, Spain, Rodríguez-Archilla Alberto , Piedra-Rosales Claudia ,   Department of Stomatology, Oral Medicine Unit. Faculty of Dentistry, University of Granada, Granada, Spain
Published: October 2021

Introduction: Diabetes mellitus is a chronic metabolic disorder that induces elevated plasma glucose levels. Diabetic patients are more susceptible to infections, especially fungal infections. There is a direct relationship between increased blood glucose levels and the number of Candida hyphae in the oral mucosa. This study aimed to evaluate oral candidiasis and the different Candida species found in patients with and without diabetes mellitus. Methods: A search for studies on oral candidiasis and diabetes mellitus was carried out in the following databases: PubMed (MEDLINE, Cochrane Library), Web of Science (WoS) and Google Scholar. For dichotomous outcomes, the estimates of effects of an intervention were expressed as odds ratios (OR) using the Mantel-Haenszel (M-H) method with 95% confidence intervals. Results: 25 studies were included in this meta-analysis. Diabetes Mellitus patients tripled the probability of being infected by Candida species (OR:3.16, p<0.001). Likewise, Candida species infections were more likely in patients with poor glycemic control (OR:2.94, p<0.001) and with dentures (OR:2.22, p<0.001). In contrast, neither gender nor diabetes mellitus type of diabetes conditioned fungal infections (p>0.05). The most prevalent Candida species in both diabetics and controls were C. albicans and C. tropicalis. Diabetics had significantly fewer C. non-albicans species oral infections than non-diabetics (p=0.04). Conclusions: Diabetics are more prone to oral candidiasis, especially C. albicans infections.
COVID-19: Potential role of prophylactic anticoagulation in preventing thrombotic events and mortality. Narrative review
Authors:   JB Iturraspe Hospital, Santa Fe, Argentina, Castro Maximiliano Gabriel , Cuevas Gisel ,   JB Iturraspe Hospital, Santa Fe, Argentina
Published: October 2021

The COVID-19 pandemic and the limited therapeutic arsenal available strain daily clinical practice. Guidelines have recently recommended routine anticoagulation of hospitalized COVID-19 patients. However, apart from the expert panels’ experience, the provenance of this recommendation is not clear, due to the scarce published evidence. We provide a narrative review with the objective of unraveling the rationale for this practice. First, we analyze the biochemical, histopathological and clinical evidence for a pro-thrombotic profile in COVID-19 patients. Then, we present the clinical data from previous studies and discuss to what extent they aid in clinical decision-making. We conclude that, in the absence of randomized controlled trials, which are of utmost importance, prophylactic-dose anticoagulation should be offered to critically ill patients hospitalized for COVID-19 pneumonia, particularly those with high d-dimer levels, since they are the population most likely to benefit from it.
Factors affecting SARS-CoV-2 (COVID-19) Pandemic, including Zoonotic, Human Transmission and Chain of Infection. Reducing Public health Risk by Serum Antibody Testing, Avoiding Screening in Unhygienic Places and False PCR Reporting. A Scientific Review
Authors:   Consultant Diabetologist and Research Scientist, Aseer Endocrine and Diabetes Center, Aseer Central Hospital, MOH, Saudi Arabia, Ahmed Aziz Kamran Mahmood , Othman Abdullah ,   Consultant Pediatric Endocrinologist and Director Aseer Endocrine and Diabetes Center, Aseer Central Hospital, MOH, Saudi Arabia, Alqahtani Waleed Abdullah ,   Consultant Adult Endocrinologist and Medical Director, Asser Central Hospital, MOH, Saudi Arabia, Azhar Sumaiya ,   Pharmacists and Medical Researcher, B. Clinical Pharmacy, University of Karachi, Pakistan
Published: October 2021

During December 2019, a rapid increase in the number of SARS-CoV-2 (COVID-19) cases was reported worldwide. We investigated several factors for rapid increase in SARS-COV-2. Genomic sequence reveals that domestic and wild animals were likely ancestors and zoonotic source for SARS-CoVs, MERS-CoVs, and SARS-CoV-2; these viruses replicated in animals and humans during past several decades, exhibiting diverse mutations and self-limiting diseases except during outbreaks. SARS-CoV-2 has been retrospectively isolated in different studies in August 2019, several months before Wuhan reported. Hence, there is a possibility that viruses went undetected and infecting sub-clinically, in past several years, and SARS-CoV-2 antigens and neutralizing antibodies may have been present in humans since years. All SARS-CoVs are basically respiratory viruses, spread by droplets, hence droplet precautions are essential. Furthermore, silent phase of transmission (asymptomatic/subclinical) can be beneficial for humans. Lack of symptoms eventually lessen virus transmission and reduce the pathogen's long-term survival and provide strong humoral herd immunity (with sropositivity and diverse antibodies) up to several years and during epidemics. RT-PCR has low sensitivity and specificity, carries a high risk of handling live virus antigens, and requires difficult protocols. As viral load also sharply declines after few days of onset of infection, this technique might overlook infection. Furthermore, SARS-CoV-2 infection may be present in blood when oropharyngeal swabs are negative by RT-PCR. Conversely, antibodies against SARS-CoVs develop robustly in by reduced amount of antigens and ELISA for diagnosing antibodies demonstrates 100% specificity and 100% sensitivity, even in clinically asymptomatic individuals. These antibodies can be used for serologic surveys, monitoring and screening. Furthermore, screening tests for SARS-COV-2 should be avoided in unhygienic public places by nasopharyngeal swabs, which carry a high risk of further transmission, co-infection or super-infection. If above mentioned factors and Infection control policy is followed, SARS-CoV-2 pandemic can be controlled effectively.
Change Management in Medical Institutions: Implementation View
Authors:   Department of Forensic Medicine and Clinical Toxicology, College of Medicine, Suez Canal University, Ismailia City, Egypt, Elshama Said Said ,   College of Medicine, Taif University, Taif, Saudi Arabia
Published: October 2021

Change is a learning process modeling the attitudes and values of the involved staff to adapt and show the change in daily work life. Leading the change in medical schools or in the health care system is considered one of the assignments of successful leadership that can achieve an effective organizational change under complex conditions. This review aims to show an implementation view about how to manage the change in medical institutions and how to overcome obstacles, and how to face the challenges. The resistance to change represents a major obstacle to the change process in any medical school or health care system. Thus, it should address this resistance by creating a suitable climate for carrying out the change based on a flexible strategy that may be translated into practical steps during the implementation. Moreover, the change should be institutionalized wherein new behaviors are persisting and generalizing in the medical school or the health care system as a result of the change application. In addition, the successful management of change in any medical school or system requires a well-functioning and efficient management system for achieving the intended results. Therefore, many benefits may be gained as a result of the success of a change process in any organization wherein it improves the effectiveness and efficiency of organizational and staff performance besides creating an opportunity for getting the best practices.
Rubinstein-Taybi syndrome: principal oral and dental disorders and literature update
Authors:   Faculty of Health and Sports Sciences, University of Zaragoza, Huesca, Spain, de la Parte-Serna Alejandro Carlos , Ortega-Soria Ricardo ,   Pediatrics Emergency Service, HLA Hospital Montpellier, Zaragoza, Spain, Oliván-Gonzalvo Gonzalo ,   Social Services Institute of Aragón, Zaragoza, Spain
Published: October 2021

Introduction: Oral and dental (OD) disorders in children with Rubinstein-Taybi syndrome (RTS) are frequent but not well-known by dentists and pediatricians due to the syndrome being extremely rare. Objective: To describe the OD findings observed in a 5-year-old girl with RTS and to update the literature. Clinical case: The patient presented the following OD manifestations: prominent lower lip, narrow mouth opening, narrow and arched palate, history of angular cheilitis, micrognathia, poor lingual motility, plaque and tartar, bleeding from gingival areas due to poor dental prophylaxis, and malocclusion in the form of an anterior open bite. These OD manifestations are seen in more than 40-60% of patients with RTS. Conclusions: Professionals who treat children with RTS should become aware of the advisability of referring them to the pediatric dentist from 1 year of age and performing check-ups every 6 months. Dental management is often difficult so collaboration with anesthesiologists is recommended in order to carry out a safe and effective treatment.
Retinitis pigmentosa associated with systemic light chain amyloidosis (AL amyloidosis)
Authors:   Department of Internal Medicine, Military Hospital of Gabes, Gabes 6000, Tunisia, Bouomrani Salem ,   Department of Internal Medicine, Sfax Faculty of Medicine, University of Sfax, Sfax 3029, Tunisia, Saadaoui Fahd ,   Department of Internal Medicine, Military Hospital of Gabes, Gabes 6000, Tunisia,   Department of Internal Medicine, Sfax Faculty of Medicine, University of Sfax, Sfax 3029, Tunisia, Ayadi Nour Elhouda ,   Department of Internal Medicine, Military Hospital of Gabes, Gabes 6000, Tunisia,   Department of Internal Medicine, Sfax Faculty of Medicine, University of Sfax, Sfax 3029, Tunisia
Published: October 2021

Retinitis pigmentosa (RP) or hereditary retinal dystrophy is a rare disease that can be isolated (non-syndromic RP) or associated with other systemic signs (syndromic RP). Kidney damage is exceptionally reported in patients with RP, particularly in syndromic forms. Association with renal amyloidosis remains unusual with only one reported case of RP and hereditary gelsolin amyloidosis due to a G654A gelsolin mutation defining the new syndrome of Ardalan-Shoja-Kiuru. Apart from this publication, no case associating RP and AL amyloidosis has been found. We report an original case of renal damage revealing kappa-type systemic light chains amyloidosis (AL amyloidosis) in 35-year-old man with sporadic RP. Our observation is, to our knowledge, the first to report this association.
Prevalence and Antibiotics Susceptibility Pattern of Urine Bacterial Isolates from Tripoli Medical Center (TMC), Tripoli, Libya
Authors:   Department of Medical Laboratories Sciences, Faculty of Medical Technology, Tripoli University, Tripoli, Libya, Ben Ashur Abir , El Magrahi Hamida ,   Department of Medical Laboratories Sciences, Faculty of Medical Technology, Tripoli University, Tripoli, Libya, Elkammoshi Asma ,   Department of Medical Laboratories Sciences, Faculty of Medical Technology, Tripoli University, Tripoli, Libya, Alsharif Hiba ,   Department of Medical Laboratories Sciences, Faculty of Medical Technology, Tripoli University, Tripoli, Libya
Published: October 2021

Introduction: Urinary tract infections (UTI) are one of the most common human bacterial infections encountered by physicians. The risk of resistant microbes is emerging as a result of the overuse of antibiotics treatments. The presence of pathogens with increased resistance to antimicrobial agents makes UTIs difficult to treat. This study was aimed at determining the prevalence of the pathogens that cause UTIs, as well as the antibiotic susceptibility of these isolates. Materials and methods: This prospective study was conducted from February 2020 to April 2020; a total number of 200 urine samples were collected from patients who daily attended TMC Libya. Bacterial pathogens were determined by bacteriological culture methods and Antimicrobial susceptibility testing was done by using the disc diffusion method. Results: Out of 200 samples, 110 cases had a positive culture. The dominant bacterial pathogens were Gram-negative that being with Escherichia coli (49, 55.68%), followed by Klebsiella pneumonia (18, 20.46%), Pseudomona aeruginosa (9, 10.23%), Proteus mirabilis (8, 9.09%), Enterobacter aerogenes (2, 2.27%), Citrobacter freundii (2, 2.27%). Gram-positive bacteria were Staphylococcus aureus 20 (90.91%) followed by S. saprophyticus (2, 9.01%) of the isolate’s strains. The isolated uropathogen showed increased levels of resistance to antibiotics. Where the Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus indicated the highest antibiotic resistance to Nitrofurantoin, Sulfamethoxazole/trimethoprim, Tetracycline, Ciprofloxacin, Metronidazole and also revealed the most sensitivity to Cefixime followed by doxycycline and ceftriaxone. Conclusions: The obtained results emphasized the emergence of highly resistant bacteria to most of the tested antimicrobials and propose the need for physicians to change their treatment pattern depending on antimicrobial susceptibility results.
A Review on the Anti-Viral Activity of Houttuynia cordata: A Possible Herb for the Management and Treatment of COVID-19
Authors:   Department of Pharmacology, JSS College of Pharmacy, Ooty, India, Rymbai Emdormi
Published: October 2021

Plants are an important source of natural products and they play a vital role in the field of medicinal chemistry and pharmaceutical science. Traditional medicines have been practiced and used for thousands of years, mostly in Asian countries, where plants are the main sources of medicine. Houttuynia cordata, a herb that belongs to the family Saururaceae, has a wide range of pharmacological activities and is used traditionally in conditions like anisolobis sores, heatstroke, lung carbuncles, malaria, scrotal abscess, tonsillitis, salammoniac poison and has also been widely accepted to possess anti-cancer, anti-oxidant, anti-hypertension, anti-inflammatory, anti-mutagenic, antibacterial, anti-viral and anti-purulent activity. Moreover, it is one of the herbs that was recognized during pandemic outbreaks, such as Severe Acute Respiratory Syndrome Coronavirus (SARS CoV) in China, virulent Newcastle Disease Virus (VNDV) in Java (Indonesia) and Newcastle (England). In this review, we briefly discuss the role of H. cordata as an anti-viral agent and the possibility of developing a dosage form against Coronavirus disease-19 (COVID-19).
Dual pathology in homeless people in the Health Area of Avilés
Authors: Pallas-Álvarez Lorena , Díez-Revuelta Álvaro , M. Jambrina Juan José , Vargas Martín L.
Published: October 2021

The main objective of the present study is to estimate the prevalence of severe mental and
substance use disorders in homeless people (HP). The work was carried out on the basis of
data obtained from a representative sample of HP in Avilés (Asturias) (n = 100) using the
International Neuropsychiatric Interview (M.I.N.I.). The results of our study reveal a close
relationship between substance use and homelessness. More than half of the HP have substance
use disorders compared to substance use problems in the general population. Psychosocial care
and the organization of a support network for the HP are discussed.
Porównanie wybranych parametrów biomechanicznych osób po upadku oraz osób, które nie uległy upadkowi
Authors:   Centralny Instytut Ochrony Pracy – Państwowy Instytut Badawczy, Tokarski Tomasz
Published: October 2021

Falling out of balance is a very common cause of accidents at work. Older workers are particularly affected by this problem. It turns out that each year nearly 1/3 of people over 65 experience a fall. Particularly vulnerable are, inter alia, people with impaired physical parameters. These unfavourable changes occur along with the progressive aging process and as a result of damage to the locomotor system. Thus, the frequency of falls increases with age, and the effects on health become more severe. The article describes research on people in the 60-67 age group. Their aim was: firstly – to compare selected biomechanical parameters (i.e. parameters of walking, eye-hand coordination, muscle strength and the ability to maintain balance) of people after a fall and people who did not fall, and secondly – to indicate those parameters that may have an influence on a greater tendency to fall. Meanwhile, the differences between the parameters obtained for both studied groups turned out to be small and statistically insignificant.
Occurrence of Plant-Parasitic Nematodes of Turfgrass in Korea
Authors: Mwamula Abraham Okki , Lee Dong Woon
Published: October 2021

Plant-parasitic nematodes are not only an important constraint on agricultural crop production, but also cause both direct and indirect damage to turfgrass, which is a ground cover plant. However, studies on plant-parasitic nematodes of turfgrass in Korea are scarce. A survey for plant-parasitic nematodes was carried out on 13 golf courses in Korea. The results yielded 28 species/taxa belonging to 16 genera and 12 families of plant-parasitic nematodes. Among the isolated species, Helicotylenchus microlobus, Mesocriconema nebraskense, Tylenchorhynchus claytoni, Mesocriconema sp., and Meloidogyne graminicola were the most prevalent species in all management zones. Twelve species were new records of plant-parasitic nematodes in Korea. Highest maximum densities were showed by T. claytoni, Paratylenchus nanus, M. nebraskense, M. graminicola, and H. microlobus. Diversity (H’), was significantly higher in fairways compared to tees and greens, though species evenness (J’) and dominance (D) showed no statistically significant differences. This information is crucial in nematode problem diagnosis, and the subsequent formulation of management strategies.
Genetic Diversity and Population Structure of the Xanthomonas campestris pv. campestris Strains Affecting Cabbages in China Revealed by MLST and Rep-PCR Based Genotyping
Authors: Chen Guo , Kong Congcong , Yang Limei , Zhuang Mu , Zhang Yangyong , Wang Yong , Ji Jialei , Fang Zhiyuan , Lv Honghao
Published: October 2021

Xanthomonas campestris pv. campestris (Xcc) is the causal agent of black rot for cruciferous vegetables worldwide, especially for the cole crops such as cabbage and cauliflower. Due to the lack of resistant cabbage cultivars, black rot has brought about considerable yield losses in recent years in China. Understanding of the pathogen features is a key step for disease prevention, however, the pathogen diversity, population structure, and virulence are largely unknown. In this study, we studied 50 Xcc strains including 39 Xcc isolates collected from cabbage in 20 regions across China, using multilocus sequence genotyping (MLST), repetitive DNA sequence-based PCR (rep-PCR), and pathogenicity tests. For MLST analysis, a total of 12 allelic profiles (AP) were generated, among which the largest AP was AP1 containing 32 strains. Further cluster analysis of rep-PCR divided all strains into 14 DNA groups, with the largest group DNA I comprising of 34 strains, most of which also belonged to AP1. Inoculation tests showed that the representative Xcc strains collected from diverse regions performed differential virulence against three brassica hosts compared with races 1 and 4. Interestingly, these results indicated that AP1/DNA I was not only the main pathotype in China, but also a novel group that differed from the previously reported type races in both genotype and virulence. To our knowledge, this is the first extensive genetic diversity survey for Xcc strains in China, which provides evidence for cabbage resistance breeding and opens the gate for further cabbage-Xcc interaction studies.
Response of Barley Genotypes to Fusarium Head Blight under Natural Infection and Artificial Inoculation Conditions
Authors: Khanal Raja , Choo Thin Meiw , Xue Allen G. , Vigier Bernard , Savard Marc E. , Blackwell Barbara , Wang Junmei , Yang Jianming , Martin Richard A.
Published: October 2021

Forty-eight spring barley genotypes were evaluated for deoxynivalenol (DON) concentration under natural infection across 5 years at Harrington, Prince Edward Island. These genotypes were also evaluated for Fusarium head blight (FHB) severity and DON concentration under field nurseries with artificial inoculation of Fusarium graminearum by the grain spawn method across 2 years at Ottawa, Ontario, and one year at Hangzhou, China. Additionally, these genotypes were also evaluated for FHB severity under greenhouse conditions with artificial inoculation of F. graminearum by conidial suspension spray method across 3 years at Ottawa, Ontario. The objective of the study was to investigate if reactions of barley genotypes to artificial FHB inoculation correlate with reactions to natural FHB infection. DON concentration under natural infection was positively correlated with DON concentration (r = 0.47, P < 0.01) and FHB incidence (r = 0.56, P < 0.01) in the artificially inoculated nursery with grain spawn method. Therefore, the grain spawn method can be used to effectively screen for low DON. FHB severity, generated from greenhouse spray, however, was not correlated with DON concentration (r = 0.12, P > 0.05) under natural infection and it was not correlated with DON concentration (r = -0.23, P > 0.05) and FHB incidence (r = 0.19, P > 0.05) in the artificially inoculated nursery with grain spawn method. FHB severity, DON concentration, and yield were affected by year, genotype, and the genotype × year interaction. The effectiveness of greenhouse spray inoculation for indirect selection for low DON concentration requires further studies. Nine of the 48 genotypes were found to contain low DON under natural infection. Island barley had low DON and also had high yield.
Early Pumping Engines in the Attercliffe-Darnall-Orgreave coalfield and the role of John Curr
Authors: Hunter John
Published: October 2021

By the mid-1700s, Attercliffe had a developed into a major industrial centre, specialising in steelmaking, and distinct from the town of Sheffield. It also had its own coalfield, which included the Barnsley Coal, valued for its steel-melting coke. The first ‘engine-drained’ coal pit at Attercliffe opened in 1747, close to the River Don and the Sheffield road. It was succeeded by a sequence of further collieries, each following the crop of the Barnsley Coal progressively eastwards towards Orgreave. Development of underground workings by separate, competing partnerships was uncoordinated, and all the collieries faced a constant struggle with inflowing water, including leakage between properties through failed barriers. Nine Newcomen-type pumping engines were eventually erected in this small coalfield during the remainder of the eighteenth century, two of which were also fitted with flywheels for coal-winding. A further four engines, of presumed Newcomen-type, were also erected for winding only. Four of the pumping engines were designed by John Curr, including the Greenland engine, which is described in detail in his book. He also designed and manufactured one of the winding engines.
The Travels of the Pentrich Engine
Authors: Williams Cliff , Grudgings Steve
Published: October 2021

The Newcomen-type pumping engine at Pentrich Colliery, Derbyshire was installed in 1791 and was one of the very last such machines to work in the UK, being replaced by electric pumps in 1915. The engine was moved to Staveley Lower Ground Colliery in 1819, returning to Pentrich twenty years later. The Science Museum were aware of the importance of the engine by the 1870s and had started negotiations with Mr Charles Maxted Haslam, the colliery owner, for its acquisition prior to the outbreak of the First World War. The Museum’s purchase of the engine was finalised late in 1919 and it was dismantled and re-erected on the ground floor of the newly constructed Science Museum building in Kensington in 1920.
Frederick Allott’s List of Colliery Drainage Adits and Fire Engines in South Yorkshire
Authors: Hunter John
Published: October 2021

The purpose of this paper is to place into the public domain, for the benefit of current and future researchers, a previously-unpublished list of ‘fi re engines’ in South Yorkshire. It was compiled by Frederick Allott, a surveyor and colliery historian who worked for the NCB in the 1950s, and is held at Sheffield Archives Office. It is accompanied by a second list of early, free-draining, colliery adits, some of which were used as delivery drifts for the engines. The historical background to the use of drainage adits in combination with pumping engines in the South Yorkshire Coalfield is outlined in this paper, and brief notes on those engines that have been identified so far are also included. The understanding of the complicated history of colliery drainage in this area is far from complete, and the discovery of both lists helps considerably with this. It is anticipated that the results of further ongoing research will be published by the author and colleagues in due course.
Rechtszekerheid en de kwalificatie van de arbeidsovereenkomst: twee stappen vooruit en een kleine stap terug
Authors: Laagland Femke , Said Samiha
Published: September 2021

Rechtszekerheid en de kwalificatie van de arbeidsovereenkomst: twee stappen vooruit en een kleine stap terug

Na 23 jaar Groen/Schoevers biedt de Hoge Raad in X/Gemeente Amsterdam nader inzicht in de beantwoording van de kwalificatievraag en de rol die de partijbedoeling daarin speelt. In de literatuur is X/Gemeente Amsterdam onthaald als hét nieuwe standaardarrest rondom de kwalificatievraag. In deze annotatie wordt het arrest besproken in het licht van het rechtszekerheidsbeginsel, aan de hand van drie aspecten: het publiekrechtelijke karakter van de casus en de invloed daarvan op de uitkomst, de tweefasentoets en de holistische weging. De auteurs onderzoeken of de Hoge Raad met X/Gemeente Amsterdam meer rechtszekerheid heeft gebracht rondom het kwalificatievraagstuk en de systematiek waarbinnen de kwalificatievraag moet worden beantwoord, en zo niet, of hier een rechtvaardiging voor is.
Tilgivelse: Å tro, formidle og skape rom for det
Authors: Kjetilstad Elisabet , Bråten Irlin , Ljones Øierud Gunnfrid
Published: October 2021

Tilgivelse er et av de helt sentrale ordene i kristendommen. I Den norske kirkes plan for trosopplæring heter det at barn og unge skal kunne «forstå seg selv og tilværelsen i lys av relasjonen til Gud, seg selv, andre mennesker og i forhold til resten av skaperverket» (Gud gir – vi deler, s. 14). Tilgivelse kan beskrives som noe som utruster barn og unge til å møte livets mange utfordringer og relasjoner med realisme og nåde. Men hvordan blir dette kommunisert for de unge som deltar i Den norske kirkes trosopplæring? Hvilken forståelse av tilgivelse møter barn og unge? Lærer de å tro på tilgivelsens betydning i eget liv? Prismet har invitert en prest og en trosopplæringsleder til å reflektere over tilgivelse og om trosopplæring med tilgivelse som tema, ut fra sine perspektiv. De to har tidligere jobbet side om side i samme menighet, men nå har presten byttet jobb til fengselsprest og har dermed fått noen nye erfaringer og refleksjoner om temaet.