bluuebunny/crossref_metadata_2025 huggingface dataset:
Business Analysis of Micro Enterprises Sector: Social Media Digital Marketing Approach
Authors: . Adriwati , Handayani Heny , . Anita
Published: June 2023

The development of information technology has an impact on the marketing of MSME products with many MSME offenders competing in the use of digital marketing. This study aims to determine the form of social media marketing used in the microbusiness sector of DKI Jakarta Province, West Java Province, and Central Java Province. This research benefit can contribute to the Microbusiness sector, which can be competitive in the global market. The study took place in 3 provinces of Indonesia, namely DKI Jakarta Province, Central Java Province, and West Java Province. The methods used were a literature review and qualitative research. The data were collected through observation, interviews, and a review of secondary data documents and metadata. The metadata is obtained from academic articles published in e-resources that are provided free of charge, in the form of articles on social media marketing and digital marketing from 2015 to 2022, for a total of 239 articles. The data analysis technique was conducted using bibliometric and qualitative methods. Bibliometric analysis was carried out with the help of the VOS Viewer application software. Qualitative data analysis was conducted by describing a collection of information obtained and analyzing the data for making conclusions, taking action, and presenting the results in the form of narrative texts, matrices, diagrams, tables, and charts. The results showed that the Provincial Governments of DKI Jakarta, Central Java, and West Java played an active role in assisting the development of microenterprises in their regions. In terms of five microbusiness offenders, they said that the local government helped them develop their businesses, especially in facilitating funding, licensing, and product promotion. Product promotion and marketing, using digital marketing and social media helps them in expanding their marketing area because they can interact with consumers through online interaction. Microbusiness offenders can also expand their market share, which also has an impact on increasing sales.
Keywords: digital marketing, social media marketing, business competition, MSMEs
Human Resource Management Strategy: Organizational Culture on Local Government Agency in using IT Governance System
Authors: Maulidza Muhammad
Published: June 2023

Nowadays, much attention is directed to IT in order to facilitate better human resource management and improve decision-making results with the factors that influence it, such as the cost of using ICT, setting regulations and the implications of reporting standards that are accurate and comprehensive, and the need to deal with increasing rate of change in organizations. IT governance is one of the main concerns of public organizations today, which seek to gain value from their ICT implementation and create a competitive advantage. Within an organization, the habit of using the IT governance system becomes the part of work culture of human resource management itself and is often associated with the organizational culture. Organizational culture as human resource management strategy is one of the various factors that influence IT governance performance in organizations. However, this topic needs a lot of in-depth research, especially in the public sector. In describing the profile of organizational culture, this research uses quantitative methods through OCAI questionnaires and semistructured interviews as a qualitative approach with the total sampling. The results of the research show that the current organizational culture on the selected local government agency during the adoption of IT governance system was dominated by the market culture. Whereas, the preferred organizational culture for the future is the adhocracy culture.
Keywords: organizational culture, organizational culture assessment instrument, IT governance, cultural analysis on IT governance
The Effectiveness of The Implementation of The ASN Corporate University Concept Integrated With The Knowledge Management System in The Development of Apparatus Human Resources Study On Yogyakarta City Government
Authors: Lumban Gaol Porman , Fernando Tumanggor Budi
Published: June 2023

The purpose of this study was to analyze the effectiveness of the application of the concept of ASN Corporate University integrated with the Knowledge Management System in the Development of Human Resources (HR) Apparatus. The benefit of this research is to contribute ideas for government agencies in knowing the effectiveness of implementing the ASN Corporate University concept in the development of human resources for apparatus supported by an effective and appropriate Knowledge Management System policy. As well as providing benefits to the academic world, namely being a contribution of knowledge and insight in terms of more appropriate policy implementation strategies by leaders in Ministries, Institutions, and Local Governments regarding the effectiveness of implementing the ASN Corporate University concept integrated with the Knowledge Management System in Apparatus HR Development. The research method used is a mixed method (mixed method). Analysis of the study conducted in the Yogyakarta area as a representation of the local government that has implemented the ASN Corporate University concept well. Data was collected by means of questionnaires, observations and in-depth interviews in the period from March to May 2022.
Keywords: ASN Corporate University, Knowledge Management System
La persona jurídica. De Savigny a la jurisprudencia
Authors: Cubillos Garzón Camilo Enrique
Published: June 2023

En el presente texto se pretende exponer en que entorno se originó el concepto de la persona jurídica y como se considera su existencia hoy en día. Luego se ahondará en la jurisprudencia y la carencia en la comprensión de su evolución. La Personalidad Jurídica no nace, sino que se hace analíticamente.
Trayectoria escolar de la cohorte de ingreso 2009 de la licenciatura en enfermería.
Authors: Vázquez Domínguez Areli , De la Cruz González Carlos , Fócil González Leticia
Published: June 2023

El estudio de la trayectoria escolar de los alumnos del pregrado, aporta datos sobre la dinámica de los estudiantes durante su estancia en la universidad desde su ingreso, permanencia, egreso y titulación. Estos datos, se constituyen en una valiosa fuente de información para la toma de decisiones, tanto para la administración del curriculum, ulteriores reestructuraciones y el aseguramiento de la calidad del Programa Educativo de la Licenciatura en Enfermería de la DACS/UJAT. Se analizó la cohorte de la última generación del plan de estudios flexible 2003, que corresponde a 186 estudiantes que ingresaron en el ciclo agosto 2009; para este estudio fueron clasificados de acuerdo a su trayectoria en egresos y no egresos, posteriormente se realizó el análisis estadístico tanto de la información sociodemográfica como de las variables de trayectoria y comportamiento escolar. En conclusión, en este estudio se encontró que aproximadamente la tercera parte de esta cohorte cae en la característica de no egreso en cuatro años; identificándose en ella un alto índice de deserciones y rezago escolar. En los estudiantes que egresaron en cuatro años, se identificó que un alto porcentaje de ellos, no aprueban en examen ordinario todas las asignaturas del PE.
The Experiences of People Living with HIV in Seeking HIV Health Services During Covid-19 Pandemic in Denpasar
Authors: Wiratama I Putu Supardika , Raya Nyoman Agus Jagat , Juniartha I Gusti Ngurah
Published: June 2023

People living with HIV (PLWH) need to maintain their health status by seeking HIV health services. However, HIV health services have been impacted by the Covid-19 pandemic and affect antiretroviral therapy (ART) for people living with HIV. This study aimed to explore the experiences of people living with HIV in seeking HIV health services during the Covid-19 pandemic. This study used a qualitative research design with a descriptive phenomenological approach. Semi-structured interviews were used on eight participants with a purposive sampling technique. Thematic analysis was used for data analysis in this study. This study found three themes, namely barriers to access to HIV health services during the Covid-19 pandemic, motivation to access HIV health services as the second theme. The third theme is the adaptation of HIV health services during the Covid-19 pandemic. PLWH have challenges accessing HIV health services during the Covid-19 pandemic. However, they have the motivation to maintain their health status by following new policies during the new normal period during the Covid-19 Pandemic. Communication, information, and education related to Covid-19 and new policies in accessing HIV health services must be provided by HIV nurses. The goal of such provision is to maintain health status, prevent lost to follow-up ART, and improve the quality of life of PLWH.
PENERAPAN PROBLEM BASED LEARNING BERBASIS PEMBELAJARAN BERDIFERENSIASI DI SMAN 1 JEMBER UNTUK MENINGKATKAN HASIL BELAJAR
Authors: Cahyani Rieneke , Komarayanti Sawitri , Hidayah Lilik
Published: June 2023

In 21st century learning requires humans to have the ability to think well, this learning must be able to trigger students' abilities to learn independently. Based on the observations of the class average value of 69.05, only 8 students reached the KKM or 23.52%. This research uses Classroom Action Research (PTK) which is conducted to improve the performance of educators regarding the quality of the learning process, and improve student learning outcomes through reflective action in the shape cycle. This research was conducted at SMAN 1 Jember with research in class X-9, totaling 34 students. The data collection technique used is a test (in the form of a written test/evaluation to collect data related to student learning outcomes). This research was conducted at SMAN 1 Jember from April to May 2023 with the material on Environmental Pollution and Accumulation of Pollutants in the Food Chain using the Problem Based Learning model based on differentiation learning. The application of a differentiated learner-based Problem Based Learning (PBL) model can improve student learning outcomes. This is shown from the results of variable data analysis. The results of data analysis on the student learning outcomes variable show that the proportion of completeness of student learning outcomes in cycle I has increased to 52.9% with an average value of 72.94, and continues to increase in the first cycle. II where the proportion of completeness of student learning outcomes reaches 94.10% with an average value obtained of 87.05
Studi Literatur: Pentingnya Pembelajaran Berdiferensiasi di Era Kurikulum Merdeka untuk Meningkatkan Hasil Belajar Peserta Didik
Authors: Insani Alamia Haque , Munandar Kukuh
Published: June 2023

The independent curriculum implements a new paradigm of learning, one of which is independent learning. Independent learning is an approach for students to be able to choose lessons according to their interests and needs. The needs and interests of each student vary and the teacher can accommodate this diversity by implementing differentiated learning. Learning that fits the needs of students through differentiated learning can improve student learning outcomes. The purpose of this research is to review the importance of differentiated learning in the independent curriculum era to improve student learning outcomes. Based on a literature review, the results of the study show that there is an effect of differentiated learning on improving student learning outcomes. Improvement of  learning outcomes as a form of implementing one or more aspects of differentiation. The differentiation aspect consists of content, process, product, and learning environment differentiation.
IMPLEMENTASI PEMBELAJARAN BERDIFERENSIASI DALAM MENINGKATKAN MOTIVASI BELAJAR PESERTA DIDIK KELAS 8 DI SMPN 2 KALISAT
Authors: Pratiwi Silvia Eka , Maftujianah Maftujianah
Published: June 2023

The low motivation of students in learning is a problem that needs to be addressed. Low learning motivation will cause students’ lack enthusiasm in learning which can directly impact student learning outcomes. Based on observations made in class VIII A of SMP Negeri 2 Kalisat, it was found that the students' motivation and enthusiasm for learning were low. Therefore, improvements are needed in learning that can overcome these problems. One of the innovative strategies that can be used as a solution to the problem of low student learning motivation is to use differentiated learning. The purpose of this study was to find out whether differentiated learning can increase students' learning motivation as well as a form of school preparation in implementing the Kurikulum Merdeka at SMP Negeri 2 Kalisat. This study used the Collaborative Classroom Action Research (PTK-K) method which consisted of activity 1, namely pre-cycle and 2 learning cycles. This study uses a qualitative descriptive analysis technique which is carried out on PTK-K data by sorting, simplifying, and grouping, focusing, organizing, and making conclusions on the data obtained. Based on research results, differentiated learning can increase students' learning motivation.This can be seen from the increase in students' learning activities, the enthusiasm of students in learning, and the satisfaction of students in learning according to the results of the interviews. Furthermore, the analysis of the results of the learning motivation questionnaire also showed an increase in learning motivation category from pre-cycle, cycle 1 to cycle 2.
Improving Freight and Commercial Work on Railway Transport: Concept and Tools
Authors: Smirnov Fedor , Novichihin Alexey , Kovalev Konstantin
Published: June 2023

Purpose: The article offers a solution to the problem of low efficiency of freight and commercial work at railway stations with a small loading volume. The goals and objectives of the national project “Digital Economy” and the program “Digital Railway” are considered. The methods of improving freight and commercial work currently used in railway transport to increase the productivity of stations and to increase workload without capital investments in infrastructure are outlined. A prospective algorithm for processing wagons on departure has been formed. The concept of improving the technology of receiving a wagon for transportation is proposed. An intelligent system for receiving wagons for transportation using a neural network has been developed. The results of the development of a program for determining the types of rolling stock in the image are shown. Methods: Methods of analysis, synthesis and neural networks, the theory of automatic control are used. Results: A solution to the problem of increasing the efficiency of the technology of receiving wagons for transportation at stations with insignificant loading volumes is proposed. Practical significance: The introduction of the developed intelligent system at railway stations will improve the quality and speed of commercial inspection when accepting a car for transportation.
Provision of Personal Protective Equipment for Employees of Transport Enterprises
Authors: Bystrov Evgeniy , Harlamova Alina
Published: June 2023

Purpose: Substantiation and development of an innovative service center for providing personal protective equipment for employees of transport enterprises. Analysis of the correlation of cases of occupational injury due to the non-use of special clothing and special protection and consideration of issues related to the need to create service centers for the storage, issuance, and cleaning of personal protective equipment. Methods: Research and analysis of regulatory documentation regulating the use and provision of personal protective equipment for employees of transport enterprises on the example of the Open Joint Stock Company “Russian Railways”. Application of the results of the statistical method of analyzing the dynamics of occupational injuries for organizational and technical reasons. Results: The functionality of service centers is proposed for consideration, as well as a brief justification of their necessity. Conclusions about the prospects of the proposed innovation are drawn. Practical significance: It is shown that the creation and implementation of service centers at railway transport enterprises will reduce the level of occupational injuries caused by the non-use of personal and collective protective equipment or the use of PPE of inadequate quality, as well as reduce the cost of premature disposal of workwear due to high-quality cleaning and repair, which in general will contribute to raising the quality of services rendered to employees of railway transport enterprises to a new level.
A história não é uma bruxa
Authors: Valle Rafael do
Published: June 2023

Neste artigo, discutiremos, a partir do confrontamento de seus ensaios e entrevistas, aquilo que a filósofa brasileira Gilda de Mello e Souza chamou de “miopia feminina”. Tal condição é fruto da cultura que condicionou as mulheres à certa produção artística e instaurou um processo criativo específico. Contudo, vemos que a autora não quer abandonar o que a história fez das mulheres, uma vez que fazer isso seria como destruir tudo que elas construíram no campo das artes. A partir disso, esboçaremos uma aproximação entre o pensamento da filósofa brasileira e a crítica feminista da história da arte. Ao fim, apresentaremos o contexto do qual parte Gilda de Mello e Souza, discorrendo sobre a condição da mulher no sistema acadêmico de sua época, a sua participação na revista Clima e a sua atuação profissional como professora de Estética no Departamento de Filosofia da Universidade de São Paulo.
Artistas negras na América Latina contemporânea
Authors: Xavier Janaina Silva
Published: June 2023

Este artigo pretende refletir sobre a produção artística latino-americana contemporânea, a partir do trabalho de mulheres negras. Com esse intuito, buscou-se fazer uma interlocução entre história e arte, levando em consideração a diversidade dos contextos da América Latina, tomando como objeto de análise as produções de três artistas negras: a colombiana Doris Salcedo (1958), a brasileira Rosana Paulino (1967) e a cubana Belkis Ayón (1967-1999). Por meio de levantamentos bibliográficos e da análise das entrevistas e depoimentos das artistas, bem como de suas obras: “Noviembre 6 y 7” (2002) de Doris Salcedo, “Bastidores” (1997) e “Assentamento” (2013) de Rosana Paulino e “A Família” (1991) e “Perfídia” (1998) de Belkis Ayón foi possível estabelecer um espaço de diálogo entre essas mulheres que manifestam suas percepções individuais apresentando uma estética que denuncia temas comuns: violência política e social, gênero, religião e racismo, mas que possibilita diferentes interpretações. Desse modo, o texto propõe uma aproximação dessa produção artística latina, evidenciando as indagações que as artistas promovem em relação às circunstâncias em que estão inseridas, mostrando problemáticas que ora se aproximam e ora se afastam e que resultam em obras artísticas desafiadoras.
Ninguém nos ensina como viver. Ana da Silva, The Raincoats e a urgência de (re)existir
Authors: Guerra Paula
Published: June 2023

Neste artigo, procuramos responder à questão levantada por Linda Nochlin “Why have there been no greatest women artists?”, aditando a essa questão uma outra: Por que razão as trajetórias femininas nas artes – e particularmente na música - são esquecidas e/ou invisibilizadas? Ao estirar a questão para o mundo da música, procuraremos compreender o que está na base desse esquecimento e/ou invisibilidade e, sequentemente, da secundarização de mulheres/bandas femininas. Primeiro, analisaremos a própria invisibilidade que afetou, durante décadas, o campo dos youth studies, em que as mulheres não apareciam ou apareciam apenas como namoradas, companheiras, groupies, uma realidade que apenas começou a mudar em meados da década de 1980. Em seguida, faremos idêntico exercício na realidade portuguesa, especialmente no pós-25 de Abril de 1974 no tocante à participação das mulheres como criadoras nos mundos das artes, com especial ênfase no indie rock e no punk. E, por fim, centramos a nossa análise na compreensão do caso paradigmático da música e da ilustradora Ana da Silva e da sua banda The Raincoats - uma banda que atualmente é considerada seminal no riot grrrl e pós-punk, mas que teve de enfrentar imensas desvalorizações e/ou omissões, o que faz com que, ainda hoje, seja tida como a next big thing pelos média da especialidade e praticamente desconhecida pela generalidade da população.
Effects of soil water-holding capacity and soil N-NO3− and K on the nutrient content, vigour and yield of cv. Tempranillo vine and the composition of its must and wine
Authors: Martínez-Vidaurre José María , Pérez-Álvarez Eva Pilar , García-Escudero Enrique , Peregrina Fernando
Published: June 2023

The aim of this study was to assess the relationships between the soil water-holding capacity (SWHC), nitrate nitrogen (N-NO3−) and extractable potassium (K) content of soil; the vine nutrient content, vigour and yield; and the quality of the musts and wines in DOCa Rioja vineyards over a five-year period (2010–2014). The SWHC, N-NO3− and extractable K content of the soil were analysed in twelve cv. Tempranillo (Vitis vinifera L.) plots. Vine yield, nutritional parameters and the K and polyphenol compounds in the musts and wines were determined. In general, both the SWHC and the soil N-NO3− content were positively correlated with the N and K content of the petiole, the shoot weight and the bunch weight, but negatively correlated with the polyphenol and anthocyanin content of the musts and wines. The K extractable content was also correlated with the K content of the petiole and with the K in the musts and wines. The SWHC, the N-NO3− and the extractable K are soil parameters which have been linked to the growth and ripening of the vine plant and to the composition of the must and wine. For DOCa Rioja agroclimatic conditions, assessment of these soil parameters would enable selecting soils that support obtaining wines of better quality.
The impact of 9P’s of marketing mix strategy towards the decision to purchase halal tourism services
Authors: Karsono Lorena Dara Putri , Salma Laila Fairuz
Published: June 2023

IntroductionHalal tourism has become one of the trends in the tourism industry, including in Indonesia. However, the research on character education-based halal tourism is still limited in number. ObjectivesThis study aims to analyze the impact of the 9P's of the Marketing Mix strategy on purchasing decisions at PT Gaido Travel & Tours, Kudus Branch, a provider of character education-based halal tourism services. MethodThis quantitative study uses convenience sampling to collect data from of 100 prospective customers who expressed interest in PT Gaido Travel & Tours, Kudus Branch, services. The questionnaire utilized a five-point Likert scale, ranging from 1 to 5, to capture participants' perceptions and opinions related to the research variables. ResultsThe result shows that all the variables ie. product, price, promotion, place, physical evidence, people, processes, productivity, and priority, positively influence purchasing decisions both individually and simultanously. Furthermore, the model in this study can explain approximately 60.6% of the variation in purchasing decision of character education-based halal tourism services. ImplicationsThe company to uphold exemplary customer service and continuously enhance the execution of the 9P's of Marketing Mix strategy. This entails fostering a culture where employees are attentive to customer needs and refining the price strategy by incorporating enticing features that aligns with industry standards.Originality/NoveltyThis study provides insights on how 9Ps of the Marketing Mix strategy can be implemented for a character education-based halal tourism services provider.
Competence-based approach to the topic «Area» in geometric origami modeling
Authors: Sokolova G. A.
Published: June 2023

Introduction. The article is devoted to the assertion of the need to develop and include in the educational process of growing personalities competence-oriented tasks provided by the technology of geometric origami modeling. Relevance. In modern mathematical education, there is an active search for improving the quality of education using competence- based approach.Purpose setting. In the scientific literature, as it turned out, no studies have been found indicating effective means of asserting a competence-based approach to the study of the topic «Area», which led to the need to develop and include in the educational process competence-oriented tasks designed within the framework of technology associated with the recognition, modification and evaluation of the area ratios of geometric shapes.Methodology and methods of the study. In theoretical studies, competence-based, environmental and synergetic, cognitive-visual approaches are considered. The method of conducting experimental work using visual and graphic means aimed at revealing the category of area as an additive scalar quantity is recreated from the analysis of geometric shapes arising during the geometric modeling of origami, which the child explores and sets their boundaries.Results. The effectiveness of the considered approach to the topic «Area» is proved.Conclusions. The scope of implementation of the research results is presented.
Spiritual and moral problems of non-professional helping activities: The «bright» and «dark» sides of volunteering
Authors: Valeeva G. V. , Khoteeva R. I. , Arpentieva M. R. , Koptyaeva S. V.
Published: June 2023

Introduction. While helping people, volunteers must have a harmonious, stable understanding of themselves and the world, a clear system of spiritual and moral guidelines, and be able to convey them to their wards, avoiding psychological burnout and deformation. This is not always possible, which indicates the need to study this problem, select, train and certify not only professional social workers, but also volunteers.Purpose setting. The purpose of the study is to comprehend the spiritual and moral problems of non-professional helping activities: the «brightˮ and «dark» sides of the activity of modern volunteers and volunteering. The destructive influence of the negative experience of life that precedes volunteering distorts the understanding of the reality, value and purpose of volunteers is dangerous even for professionals, and especially dangerous for volunteers. Such experience, associated illusions and negative assessments increase cases of «infection» with states and forms of reaction that are destructive for the formation and development of a person, increasing vulnerability to states of psychological burnout and deformation of personal, interpersonal and professional development.Methodology and methods of the study. The research method is a theoretical analysis of the spiritual and moral problems of volunteering. The methodological basis of the study is the papers of scientists who have studied volunteering as a kind of helping, prosocial behavior.Results. The spiritual and moral problems of career volunteers' activities are related with their focus on the task and latent hostility: the tendency to confuse goals and means, grumbling and latent cruelty in contrast to event volunteers» numerous illusions and «rose-tinted glasses» in the understanding of themselves and the world. They are also associated with negative personal experience that actively deforms the understanding of self-consciousness and worldview while ignoring a number of situations that require reflection and correction.Conclusions. It is necessary to develop programs for the (re) training of volunteers, helping them to avoid processing illusions and transform deformations that manifest themselves in aggression and other incorrect ways of behavior.
Features of creating distance learning technologies in teaching foreign languages at university: Analysis of experience
Authors: Proskura Ya. V.
Published: June 2023

Introduction. For the effective organization of the educational process during distance learning of foreign languages in the conditions of a pandemic, special technical, psychological, and pedagogical retraining is required for the transition to distance learning for both teachers and students.Purpose setting. Thus, it is necessary to study the current state of distance learning in foreign languages, both in Russia and abroad, and analyze the prospects for the development of this form of education, taking into account factors that positively affect the acquisition of a foreign language. To date, a lot of attention is paid to distance learning, as, probably, none of the many ways of learning using technology. Modern research in education, and in particular in information and communication technologies, tends to use technological resources to the maximum and use them effectively in pedagogy. In the field of foreign language teaching, much has been done to cover various languages of the world, but attempts are constantly being made to find new solutions, taking into account the specific needs of language learners.Methodology and methods of the study. This article is based on our experience of creating and implementing distance English courses at the Siberian Institute of Management – a branch of the Russian Academy of National Economy and Public Administration, which uses distance learning and provides academic programs both traditionally and remotely. The article presents the technological aspect of the distance learning system, common to all courses and discuss the main features of teaching a foreign language. The process of developing and implementing English language courses is considered from the point of view of the overall design of the course, the choice of teaching materials, technological and pedagogical processing of course materials, the role of the teacher, support and motivation of students, assessment of academic performance, evaluation of the course and key differences between the two methods of provision that need to be taken into account.Results. The article notes shortcomings and difficulties of a technological and pedagogical nature, as well as problems and new steps in improving English language courses.Conclusions. In conclusion, the complexity of the related technological, organizational and, no less importantly, pedagogical problems is emphasized, but we also hope to provide a reliable starting point for more ambitious projects related to distance learning and teaching foreign languages.
On the Constant Terms of Certain Laurent Series
Authors: Brent Barry
Published: June 2023

We study the divisibility properties of the constant terms of certain meromorphic modular forms for Hecke groups and relate those properties to several O.E.I.S. sequences and several other sequences, the members of which appear in congruences of Ramanujan. At the end of the article, we construct from elementary arithmetic functions some meromorphic but not necessarily modular functions and study their constant terms. For our use in subsequent drafts, we work out a variation of the multinomial theorem convenient for application to single-variable power series.
Test-Retest Repeatability of Human Gestures in Manipulation Tasks
Authors: Digo Elisa , Caselli Elena , Polito Michele , Antonelli Mattia , Gastaldi Laura , Pastorelli Stefano
Published: June 2023

The importance of performance excellence and operator’s safety is fundamental not only when operators perform repetitive and controlled industrial tasks, but also in case of abrupt gestures due to inattention and unexpected circumstances. Since optical systems work at too low frequencies and they are not able to detect gestures as early as possible, combining the use of wearable magneto-inertial measurement units (MIMUs) with the adoption of deep learning techniques can be useful to instruct the machine about human motion. To improve the initial training phase of neural networks for high classification performance, gestures repeatability over time has to be verified. Since test-retest approach has been poorly applied based on MIMUs signals in a context of human-machine interaction, the aim of this work was to evaluate the repeatability of pick-and-place gestures composed of both normal and abrupt movements. Overall, results demonstrated an excellent test-retest repeatability for normal movements and a fair-to-good test-retest repeatability for abrupt movements. Moreover whereas the reduction of time between test and retest sessions increased repeatability indices.. In detail, results of the test suggested how to improve the reinforcement learning for the identification of gestures onset, whereas results of the retest gave important information about the time necessary to retrain the network.
Desiccant Technologies for Improving Air Quality: An Overview of the Brazilian Scenario and Comparison of Available Design Software
Authors: Castillo Santiago York , Nunes Bruno Gomes , Fontana Geovani Souza , Busanello Daiane , Santos Alexandre Fernandes , Santos Samuel Moreira Duarte , Mello Estefania Neiva de , Sphaier Leandro A.
Published: June 2023

A review of desiccant dehumidification technologies for improving air-quality has been presented, especially focusing on alternatives for air conditioning systems for minimizing the Sick Building Syndrome. The principles and types of desiccant wheels, as well as the existing selection software for these types of equipment, were reviewed and comparatively evaluated. The study focuses on the Brazilian context, therefore, information about air condition systems and laws of this country were evaluated. Possible applications of desiccant wheels are also analyzed, such as their integration into cooling cycles and the sensible heat wheel. Finally, several commercial desiccant wheel selection software were evaluated, which are useful in many situations. Nevertheless, it was evidenced that the available softwares are not capable of performing an operation analysis for only a specific period. Therefore, it is essential to create computational tools to select desiccant wheels, considering the data from the different Brazilian regions for a year.
Effects of variated final temperature and workpiece thickness for hot rolling of aluminum alloy EN AW-8011
Authors: Kraner Jakob , Cvahte Peter , Šuštarič Primož , Šuštar Tomaž , Donik Črtomir , Paulin Irena , Kim Shae K , Kim Kyung Il
Published: June 2023

The hot rolling in the process chain of the aluminium rolled products present the critical element of material quality and influence on productivity. The desire to increase the letter demand modifications of hot rolling, consequential changes of microstructure, crystallographic texture, mechanical and formability properties must be knowledge and consistently considered in planning the rolling process and rolled product. Achieving lower thicknesses of the hot-rolled band would enable fewer passes with cold rolling; consequently, hot rolling with the same number of passes will complete with lower temperatures. Microstructural and texture characterization with the optical microscope and scanning electron microscope for the hot-rolled band 3.25 mm the smaller grains appeared in the center of the cross-section, unlike for the hot-rolled band 6 mm, the smaller grains were detected on the upper and bottom position of the cross-section. Furthermore, the comparison shows also that the hot-rolled band 6 mm has 64 % of random texture components and 83 % of recrystallized grains, and the proportional adjustment for the hot-rolled band 3.25 mm has the 42 % of random texture components and 55 % of recrystallized grains. For the mechanical testing results, the elongation values in rolling and transverse directions significantly differ just in the case of a hot rolled band of 3.25 mm. Consequently, the earing results are more than 1.5 % higher for the hot-rolled band, 3.25 mm, than the hot-rolled band, 6 mm.
Sudden Death of Cattle Caused by Babesia bovis Transmitted by Rhipicephalus microplus (Acari: Ixodidae) Ticks
Authors: Luo Jin , Chen Zhen , Guo KaiFei , Lou DengJi , Han Rong , Che Liyan , Gou Mengyang , Guan Guiquan , Luo Jianxun , Yin Hong , Liu Guangyuan
Published: June 2023

In this study, a case of acute cattle death was investigated. The pathogen was identified, and its molecular characteristics and vector were analysed. This study provides a reference for the prevention and control of babesiosis and the healthy breeding of cattle. In this study, unengorged and engorged Rhipicephalus microplus ticks were collected from the Chongqing area. The unengorged ticks were cultured on cattle under laboratory conditions, and the engorged ticks were cultured to lay eggs. In the process, the cattle suddenly died at 12 days from the bite of an unengorged R. microplus tick. In addition, the larvae hatched from R. microplus eggs, which were cultured on the other cattle, and the experimental cattle died in approximately 14 days. Blood was collected from a second dying and stored at 4 ℃ for one week. Two millilitres of anticoagulated blood was injected subcutaneously into the third cow without piriformis infection. On the fourth day, the body temperature rose to 41 ℃ with slight lymphadenopathy. On the fifth day, the cow suddenly fell and died approximately 4 hours later. DNA was extracted from the blood of all dead cattle and amplified by PCR with piriformis universal primers. The results showed that the cattle were infected with Babesia bovis. The phylogenetic tree based on 18S rRNA showed that the Chongqing strain of B. bovis, which caused the death of cattle, was closely related to the Yunnan strain in China and had the same taxonomic status as the Spanish strain. This case report will draw people's attention to B. bovis once again, and positive control measures should be taken to reduce the losses of farmers to achieve the goal of healthy breeding.
Decomposed Fuzzy Sets and Their Usage in Multi-Attribute Decision Making: A Novel Decomposed Fuzzy TOPSIS Method
Authors: Kahraman Cengiz , Cebi Selcuk , Oztaysi Basar , Cevik Onar Sezi
Published: June 2023

Decomposed fuzzy sets are the resent extension of intuitionistic fuzzy sets by incorporating functional and dysfunctional points of views to the definition of membership functions. This paper extends the Technique of Order Preference Similarity to the Ideal Solution (TOPSIS) method to the Decomposed Fuzzy TOPSIS (DF TOPSIS) method and applies it to a multi-criteria risk-based supplier selection problem under fuzziness. DF TOPSIS involves finding a positive ideal solution and a negative ideal solution and measuring the distance of each alternative to these solutions. The final ranking is obtained based on the proportion of distances to the positive and negative ideal solutions. The developed DF TOPSIS method incorporates the accuracy and consistency of expert judgments, enhancing the decision-making process. A sensitivity analysis is also presented in order to show the robustness of the obtained rankings by DF TOPSIS.
Transcutaneous Spinal Cord Stimulation Facilitates Respiratory Functional Performance in Patients with Post-acute COVID-19
Authors: Ovechkin Alexander , Moshonkina Tatiana , Shandybina Natalia , Lyakhovetskii Vsevolod , Gorodnichev Ruslan , Moiseev Sergey , Siu Ricardo , Gerasimenko Yury
Published: June 2023

Background: A growing number of studies have reported Coronavirus disease (COVID-19)-related to both respiratory and central nervous system dysfunctions. This study evaluates the neuromodulatory effects of spinal cord transcutaneous stimulation (scTS) on the respiratory functional state in healthy controls and patients with post-COVID-19 respiratory deficits as a step toward the development of a rehabilitation strategy for these patients.; Methods: In this before-after, interventional, case-controlled clinical study, ten individuals with post-acute COVID-19 respiratory deficits and eight healthy controls received a single twenty-minute-long session of modulated monophasic scTS delivered over the T5 and T10 spinal cord segments. Forced Vital Capacity (FVC), Peak Forced Inspiratory Flow (PIF), Peak Expiratory Flow (PEF), Time-To-Peak of Inspiratory Flow (tPIF), and Time-To-Peak of Expiratory Flow (tPEF) were assessed before and after the intervention; Results: In COVID-19 group, the scTS intervention led to significantly increased PIF (p= .040) and PEF (p= .049) in association with significantly decreased tPIF (p= .035) and tPEF (p= .013). In the Control Group, the exposure to scTS also resulted in significantly increased PIF (p= .010) and significantly decreased tPIF (p= .031). Unlike the results in COVID-19 group, there was significantly decreased PEF (p= .028) in association with significantly increased tPEF (p= .036). There were no changes for FVC after scTS in both groups (p= .67 and p= .503); Conclusions: In post-COVID-19 patients scTS facilitates excitation of both inspiratory and expiratory spinal neural networks leading to an immediate improvement of respiratory functional performance. This neuromodulation approach could be utilized in rehabilitation programs for patients with COVID-19 respiratory deficits.
Clinical and Epidemiological Risk Factors Associated with Hospitalization and Mortality Rate of COVID-19 Patients in Banja Luka County: Retrospective Observational Cohort Study on 40,000 patients
Authors: Pilipović-Broćeta Nataša , Todorović Nevena , Škrbić Ranko , Aćimović Jela , Štrbac Savka , Soldatović Ivan
Published: June 2023

Background and Objectives: Since the beginning of COVID-19 pandemic, the infection primarily affected patients with following chronic conditions: cardiovascular disease, hypertension, chronic obstructive pulmonary disease, diabetes mellitus, obesity and cancer. The aim of this study was to explore clinical and epidemiological characteristics associated with COVID-19 outcomes in patients at the primary health care centre from March 2020 to September 2022. Materials and Methods: The study included 40,692 citizens of Banja Luka County, Bosnia and Herzegovina, who were confirmed and registered as RT-PCR positive on COVID-19. Differences regarding the distributions of patients between groups were analysed using Pearson chi square test and Mantel-Haenszel chi square test for trends, while differences in mean values were compared using independent samples t test. Relationship between mortality and independent variables were examined using logistic regression. Results: Out of 40,692 COVID-19 positive patients, 7.76% were hospitalized. The average age of hospitalized patients was significantly higher than the age of non-hospitalized patients (64.2±16.1 vs. 45.4±18.7; p<0.001). The average age of patients with lethal outcome was nearly twice higher compared to patients with non-lethal outcome (74.6±11.5 vs. 45.7±18.6; p<0.001). Male patients had higher hospitalization and mortality rate, compared to females (9.8% vs. 5.9%, p<0.001; 4.8% vs. 3%, p<0.001, respectively). The highest hospitalization rate was in patients with chronic renal failure, diabetes and cardiovascular diseases, while the death rate was the highest among patients with CRF and hearth comorbidities. Fever, cough, fatigue, nausea and vomiting, chest pain, shortness of breath and appetite loss favoured hospitalization. Patients with fatigue and appetite loss had higher percentage of lethal outcome. Vaccinated patients had significantly lower rate of lethal outcome. Conclusions: Clinical symptoms, signs and outcomes, are posing as predictive parameters for further management of COVID-19. Vaccination has an important role in clinical outcomes of COVID-19.
Electron-Beam Pumped UVC-Emitters Based on (Al, Ga)N Material System
Authors: Jmerik Valentin , Kozlovsky Vladimir , Wang Xinqiang
Published: June 2023

Powerful emitters of the ultraviolet C (UVC) light in the wavelength range of 230-280nm are necessary for the development of effective and safe optical disinfection technologies, high-sensitive optical spectroscopy and non-line-of-sight optical communication. This review considers such UVC-emitters with electron-beam pumping of heterostructures with quantum wells in the (Al,Ga)N material system. The important advantages of these emitters include the absence of the critical problem of p-type doping and the possibility of achieving record (up to several tens of watts for peak values) output optical power values in the UVC range. The review consistently considers about a decade of world experience in the implementation of various UV emitters with various types of thermionic, field-emission, and plasma-cathode electron guns (sources) used to excite various designs of active (light-emitting) regions in heterostructures with quantum wells AlxGa1-xN/AlyGa1-yN (x = 0 − 0.5, y = 0.6 − 1) fabricated either by metal-organic chemical vapor deposition or by plasma-activated molecular beam epitaxy. Special attention is paid to the production of heterostructures with multiple quantum wells/two-dimensional(2D) quantum disks GaN/AlN with a monolayer (1ML ~ 0.25nm) thickness, which ensures a high internal quantum efficiency of radiative recombination in the UVC range, low elastic stresses in heterostructures, and a high output UVC-optical powers.
Inhibitors of Farnesyl Diphosphate Synthase and Squalene Synthase: Potential Source for Anti-Trypanosomatidae Drug Discovery
Authors: Pone Kamdem Boniface , Fekam Boyom Fabrice
Published: June 2023

Trypanosomatids are mainly responsible for leishmaniasis, sleeping sickness, and Chagas disease, which are the most challenging among the neglected tropical diseases due to the problem of drug resistance. Although problems of target deconvolution and polypharmacology are encountered, a target-based approach is a rational method for screening drug candidates targeting a biomolecule that causes diseases. The present study aims to summarize the latest information re-garding potential inhibitors of squalene synthase and farnesyl phosphate synthase with anti-Trypanosomatidae activity. The information was obtained by referencing textbooks and major scientific databases from their inception until April 2023. Based on in vitro experiments, more than seventy compounds were reported to inhibit squalene synthase and farnesyl diphosphate synthase. Among these compounds, more than 30 were found to be active in vitro against Trypanosomatidae, inferring that these compounds can be prospected as scaffolds for the development of new drugs against trypanosomatid-related infections. Over-all, natural and synthetic products can inhibit enzymes that are crucial for the survival and virulence of trypanosomatids. Moreover, in vitro experiments have confirmed the activity of more than half of these inhibitors using cell-based as-says. Nevertheless, additional studies on the cytotoxicity, pharmacokinetics, and lead optimization of potent anti-Trypanosomatid compounds should be investi-gated.
MLL1 Inhibition Enhances the Differentiation Potential of Bovine Embryonic Stem Cells by Increasing H3K4 Mono-Methylation at Active Promoters
Authors: Chen Li , Xuejie Han , Jing Wang , Fang Liu , Yuanyuan Zhang , Zihong Li , Zhenyu Lu , Yongli Yue , Jinzhu Xiang , Xueling Li
Published: June 2023

Mixed lineage leukemia 1 (MLL1) introduces 1-, 2- and 3-methylation into histone H3K4 through the evolutionarily conserved set domain. In this study, bovine embryonic stem cells (bESCs, named bESCs-F7) were established from the in vitro fertilized (IVF) embryos by Wnt signaling inhibition, while its contribution to endoderm in vivo is limited. To improve the quality of bESCs, MM-102, an inhibitor of MLL1, was applied to the culture. The results showed that MLL1 inhibition along with GSK3 and MAP2K inhibition (3i) at the embryonic stage did not affect bESCs establishment and pluripotency. MLL1 inhibition improves the pluripotency and differentiation potentials of bESCs via up-regulation of stem cell signaling pathways such as PI3K-Akt and WNT. MLL1 inhibition decreases H3K4me1 modification at promoters in bESCs and altered the distribution of DNA methylation in bESCs. In summary, MLL1 inhibition enables bESCs to acquire better pluripotency, and its application may provide high quality pluripotent stem cells for domestic animals.