bluuebunny/crossref_metadata_2025 huggingface dataset:
US-Entertainment-Industrieverbände gegen Youtube-DL, VPN-Streaming und Musik in Let’s-Play-Videos
Authors: Fischer Georg
Published: September 2023

Die Musik- und Filmindustrie kämpft an verschiedenen Fronten um die Verwertung von Urheberrechten – und gegen mutmaßliche Piraterie. Die Aktionen betreffen das Video-Download-Werkzeug Youtube-DL, Streaming via VPN-Tunnel sowie Musik in Let’s-Play-Videos auf der Gaming-Plattform Twitch.
Creative Commons-FAQs auf Deutsch verfügbar
Authors: iRights.info Redaktion
Published: September 2023

Creative Commons bietet seit kurzem eine umfangreiche deutsche Hilfeseite an. Diese liefert Antworten auf oft gestellte Fragen rund um CC und hilft allen, die konkrete Anliegen zu den offenen Lizenzen haben. Auch aktuelle Fragen mit CC-Bezug, etwa zu Datenbanken und Künstlicher Intelligenz (KI), werden behandelt. Rund 130 oft gestellte Fragen und ihre Antworten zu Creative Commons liegen nun auf Deutsch vor.
Per Christiansen über die Grenzen der Meinungsfreiheit: „Auf den Kontext kommt es an“
Authors: El-Auwad Maya
Published: September 2023

Hatespeech und Hetze sind im Netz heute leider alltäglich. „Das wird man doch noch sagen dürfen“ ist eine häufige Rechtfertigung. Doch was ist rechtlich erlaubt und was nicht? Was darf man in Sozialen Netzwerken sagen? Und wie lässt sich mit Hass im Netz umgehen? Eine rechtliche Einordnung mit dem Anwalt Per Christiansen.
Wie eine Verwertungsgesellschaft funktioniert
Authors: Fischer Georg
Published: September 2023

Verwertungsgesellschaften sind Organisationen, die im Namen ihrer Mitglieder Urheberrechte vertreten, Vergütungen für Werknutzungen einsammeln und nach bestimmten Schlüsseln an die Urheber*innen ausschütten. Wie das genau abläuft und aus welchen Quellen die Vergütungen kommen, erklärt dieser Text. Die GEMA ist nicht nur eine politische Interessensvertretung der Musikindustrie.
Verstößt Artikel 17 der EU-Urheberrechts-Richtlinie gegen EU-Grundrechte?
Authors: Steinhau Henry
Published: September 2023

Die Gesellschaft für Freiheitsrechte (GFF) veröffentlichte jüngst eine Studie zum Artikel 17 der EU-Urheberrechts-Richtlinie. Sie konstatiert, dass mehrere Regelungen grundrechtswidrig seien, etwa weil sie die Meinungsfreiheit gefährden oder eine unzulässige Überwachungspflicht vorsehen. Wir fragten nach bei den Studien-Autor*innen, Julia Reda und Joschka Selinger.
Creative Commons: Was tun bei Lizenzverstößen? Wie setze ich meine Rechte durch?
Authors: iRights.info Redaktion
Published: September 2023

Creative-Commons-Lizenzen ermöglichen es, kreative Inhalte rechtssicher und unter festgelegten Bedingungen zu nutzen. Doch was, wenn Nutzer*innen gegen Lizenzbedingungen verstoßen? Wie kann man bei CC mit Verwertungsgesellschaften zusammenarbeiten? Wir haben Antworten zu diesen Fragen zusammengestellt. iRights.info berichtet und informiert seit Jahren über Creative Commons.
Daten und Creative-Commons-Lizenzen – Trainingsmaterial für Künstliche Intelligenz
Authors: iRights.info Redaktion
Published: September 2023

Auch Forschungsdaten und Datenbanken lassen sich mit Creative-Commons-Lizenzen frei nachnutzbar machen. Sie können etwa für die Entwicklung neuer Technologien als Trainingsmaterial für Künstliche Intelligenz oder Machine Learning eingesetzt werden. Was es dabei zu beachten gilt, stellen wir im fünften Teil der CC-FAQs vor. iRights.info berichtet und informiert seit Jahren über Creative Commons.
NFTs verändern den Handel mit digitaler Musik und Kunst: Fordern sie auch das Urheberrecht heraus?
Authors: Golka Philipp
Published: September 2023

Mit NFTs werden digitale Kunstwerke, gefilmte Sportszenen oder sogar einzelne Tweets zu handelbaren Gütern, die sich sammeln und versteigern lassen. Urheberrechtliche Fragen, wie etwa zu Schrankenbestimmungen, sind teils noch ungeklärt. Zeit für eine Einschätzung eines akuten Internet-Phänomens.
Im Maschinenraum der digitalen Gesellschaft: Monika Dommann über Datencenter in der Schweiz
Authors: Frenking Lena Schulze
Published: September 2023

Wo werden unsere digitalen Daten eigentlich gespeichert? Wie werden sie transportiert? Und was kostet das alles? Die Historikerin Monika Dommann kennt Antworten auf diese Fragen, sie sucht in der Schweiz nach den Spuren digitaler Infrastruktur. Lena Schulze Frenking hat sie zu ihrem neuen Buch „Data Centers

“

befragt.
Harald Müller: „Die Tätigkeiten, die die Verlage für sich reklamieren, kann die Wissenschaft auch selbst organisieren“
Authors: Steinhau Henry
Published: September 2023

Der Bibliothekswissenschaftler Harald Müller sieht es als vorrangig, dass die Erkenntnisse öffentlich finanzierter Wissenschaft zum einen offen und breit zugänglich sind, zum anderen langfristig frei verfügbar bleiben. Ein Interview über Open Access und die Rolle von Fachverlagen und Archiven.
Mit der Lizenz zum Lesen: Was E-Books von physischen Büchern unterscheidet
Authors: El-Auwad Maya
Published: September 2023

Buch ist nicht gleich (E-)Buch: Wer ein gedrucktes Buch kauft, erwirbt auch das Eigentum – und darf damit grundsätzlich machen, was er oder sie will. Nicht so bei elektronischen Büchern: Hier sind die Befugnisse begrenzt. Wo die Unterschiede liegen und was man mit E-Books eigentlich machen darf und was nicht, erläutert dieser Text. Texte genießen als sogenannte „Sprachwerke“ urheberrechtlichen Schutz.
Mini-Umfrage: Wie gefällt Ihnen iRights.info?
Authors: Fischer Georg
Published: September 2023

Mit iRights.info möchten wir informieren, aufklären und berichten – rund um die Themen Urheberrecht und kreatives Schaffen in der digitalen Welt. Eine kurze Umfrage hilft uns dabei, unsere Leserschaft besser zu verstehen und unser Informationsangebot zu verbessern. Liebe Leserinnen und Leser, bereits seit 2005 berichtet iRights.info über aktuelle Fragen zum Urheberrecht und kreativem Schaffen in der digitalen Welt.
Großverlag Wiley übernimmt Open-Access-Vermittler Knowledge Unlatched
Authors: iRights.info Redaktion
Published: September 2023

Der US-amerikanische Wissenschaftsverlag Wiley kauft den Open-Access-Vermittlungsdienst Knowledge Unlatched. Die Übernahme steht für einen größeren Trend: Großverlage versuchen zunehmend, Open Access zu kommerzialisieren und neue Geschäftsfelder zu entwickeln.
Webinar am 22.6.: „Rechtliche Dimensionen bei der betrieblichen Nutzung Künstlicher Intelligenz“
Authors: Fischer Georg
Published: September 2023

Setzen Unternehmen Künstliche Intelligenz ein, ergeben sich nicht nur technische, sondern auch rechtliche Fragen. Zum Beispiel, welche personenbezogenen Daten verarbeitet werden dürfen oder wem die Ergebnisse der KI gehören. Ein Webinar mit den iRights.Law-Anwälten Per Christiansen und Till Kreutzer bespricht und klärt Fragen zu KI in Unternehmen.
Systematic Literature Review: Motorcycle Simulators
Authors: Wildner Dorothea , Diermeyer Frank
Published: September 2023

An increasing number of researchers have started to focus on motorcyclists. An important tool hereby is the use of motorcycle simulators. They can be used to evaluate human-machine interfaces, design future advanced riding systems like forward collision warning, or determine an optimal ergonomic position to reduce mental loads and stress. However, compared to the automotive sector, only a few simulators exist, but they differ greatly. Therefore, this literature review provides an overview of the current state-of-the-art powered two-wheeler simulators. A total of 13 simulators are described in detail, as well as their prioritized research areas, conducted studies, strengths and limitations, their development over the recent years, and their validation.
Development of a Hardware-in-the-Loop Test Bench for Validation of an ABS System on an e-Bike
Authors: Ramosaj Nicolas , Fusco Christian , Viennet Emmanuel
Published: September 2023

This work presents the development of a Hardware-in-the-Loop (HIL) test bench that can be used to validate an electric bicycle (e-bike) anti-lock braking system (ABS) for different test scenarios. The approach involves interfacing a virtual bicycle simulation model running on a real-time target machine with the physical ABS hardware under test. This setup allows to test and evaluate ABS behavior in a safe and reproducible way, before starting testing on the track. This article describes the derivation of an equation-based model considering six degree-of-freedom (dof) representing the in-plane longitudinal dynamics of an e-bike. The simulation model is experimentally validated against measurements made on an instrumented test bike. The test apparatus used and the comparison of simulation results with measurements are presented. The characteristics of the HIL test bench developed are presented, and its applicability to an ABS validation process is illustrated by evaluating the braking performance of an ABS tested on a crossover bike.
The Comparison of the Podocyte Expression of Synaptopodin, CR1 and Neprilysin in Human Glomerulonephritis: Could the Expression of CR1 be Clinically Relevant?
Authors:   Department of Nephrology, Transplantology and Internal Diseases, Karol Marcinkowski University of Medical Sciences, Poznan, Poland, Niemir Zofia I. , Perkowska-Ptasinska Agnieszka , Durlik Magdalena ,   Department of Transplantation Medicine and Nephrology, Transplantation Institute, Warsaw, Poland, Kaczmarek Elzbieta ,   Department of Clinical Pathomorphology, Karol Marcinkowski University of Medical Sciences, Poznan, Poland, Kubiak-Wlekly Anna , Olejniczak Pawel , Rochowiak Aleksandra , Czekalski Stanislaw ,   Department of Nephrology, Transplantology and Internal Diseases, Karol Marcinkowski University of Medical Sciences, Poznan, Poland
Published: September 2023

Podocytes are considered as the most important cells that determine loss of structure and function of the glomerular filter. We compared the expression of three podocyte markers, i.e.: synaptopodin (SYN), CR1 and neprilysin (NEP) in 107 patients with different forms of glomerulonephritis (GN) and 5 normal kidneys (NK). A quantitative immunohistochemistry was applied to evaluate the expression of podocyte proteins. The results were related with serum creatinine (Scr), estimated glomerular filtration rate (eGFR) and urinary protein. We observed the reduction in the podocyte expression of NEP, SYN and CR1 in proliferative and non-proliferative forms of GN. Interestingly, in mesangial proliferative GN (MesPGN), the expression of SYN and CR1 was lower in IgA-MesPGN than in non-IgA-MesPGN (p<0.005 and p<0.02, respectively). In all the patients, the expression of NEP and SYN was positively related (r=0.53, p=0.02) as that of NEP and CR1 (r=0.39, p=0.04). Yet, clinical correlations with Scr (r=-0.33, p=0.03) and eGFR (r=0.26, p=0.05) were obtained only with respect to CR1. In conclusion, SYN, CR1 and NEP may be used as markers of podocyte loss in patients with GN. However, in agreement with previous studies, the clinical relevance draws a special attention to the expression of CR1.
Annual International Geographic Medicine Congress Meetings in Shiraz, Iran: Publication Rates during 1999-2006
Authors:   Tri-State Institute of Pharmaceutical Science, Huntington, West Virginia, USA, Ghafourifar Pedram , Nader Forouz ,   Department of Community Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran, Mousavizadeh Kazem ,   Department of Basic Sciences and Cellular and Molecular Research Center, Iran
Published: September 2023

The present study aimed to examine which portion of abstracts presented between 1999 to 2006 at Annual International Geographic Medicine Congress meetings in Shiraz, Iran, were published during 1999-2006, and to identify factors affecting publication rate of those abstracts. Two hundred fifty abstracts were reviewed and categorized according to the type of presentation, study design, sample size, main findings, source of funding, and statistical significance of the results. Principal investigators of those abstracts were provided with a questionnaire inquiring whether their abstracts lead to full-length publications in peer-reviewed journals indexed under PubMed. One hundred twenty five authors responded to the questionnaire. The publication rate of the meeting presentations was found 27.2%. Statistically significant associations were found between publication rate and certain characteristics of the presentations including type of the study, achieving positive results, and conducting multi-center trial funded by a sponsor. Insufficient fluency in English, insufficient time to prepare the manuscript, and assuming journals are unlikely to accept those studies were most common reasons for not preparing or submitting the manuscripts. The publication rate of research studies presented in this annual scientific meeting in Shiraz, Iran, is lower than many similar meetings in other countries.
Adsorptive Stripping Anodic Voltammetric Determination of Thioctic Acid in Bulk and Pharmaceutical Formulations
Authors:   Department of chemistry, College of Science, King Saud University (Girls), Riyadh, Saudi Arabia, Alarfaj Nawal A.
Published: September 2023

The electrochemical behavior of thioctic acid at the hanging mercury drop electrode was studied in different supporting electrolytes. In Britton - Robinson buffer pH 3.29, the square - wave adsorptive anodic stripping voltammogram of thioctic acid exhibited a single well - defined anodic peak at about -0.21 V . vs Ag/AgCl .The peak response was characterized with respect to pH, preconcentration time , accumulation potential, supporting electrolytes, frequency, scan increment and pulse amplitude. Under the optimized conditions, a fully validated, simple, high sensitive, precise and inexpensive square - wave adsorptive anodic stripping voltammetric procedure was described for determination of thioctic acid in bulk form and tablets. The obtained results were in good agreement with those obtained with the reference method. The calibration graph was linear over the range 5 × 10-8 - 9 × 10-7 M (r=0.9997) with accumulation for 60 s at -0.4 V vs Ag/AgCl and the detection limit was ca. 1.2 × 10-8 M.
The Effects of Meperidine Analgesia during Labor on Fetal Heart Rate
Authors:   Department of obstetrics & gynecology, Shahid Sedughi hospital, Shahid Sedughi University of Medical Sciences and Health Services, yazd, Iran, Sekhavat Leila , Behdad Shecoofah ,   Department of Anesthesiology, Shahid Sedughi hospital, Shahid Sedughi University of Medical Sciences and Health Services, yazd, Iran
Published: September 2023

To estimate the effects of intramuscular meperidine analgesia on fetal heart rate (FHR) patterns compared with placebo. In a prospective randomized study, 150 healthy women with singleton term pregnancy requesting analgesia during active labor were planned to receive either intramuscular meperidin 50 mg (meperidin group) or normal saline (control group) when they requested analgesia. Fetal heart rate patterns occurring within 40 minutes of initiation of labor analgesia were retrospectively read by maternal fetal medicine specialist who was blind to type of labor analgesia. Meperidine, compared with placebo, was associated with statistically significantly less beat to beat variability (absent or less than 5 beats per minute) (28% versus 5% of fetuses, P<0.05), lower proportion of accelerations (37.3% versus 17.3% P<0.05) and of the FHR. Also FHR deceleration was significantly more than control group (25.5% versus 4%, P<0.05). Meperidine has deleterious effects on FHR.
Evaluation of hypolipidaemic activity of Capparis decidua
Authors:   MDPG College, Sriganganagar, Rajasthan, India, chahlia Neelkamal
Published: September 2023

Background: The effect of various extracts (50% ethanolic) of Capparis decidua on lipid profile of streptozotocin diabetic rats was studied. Procedure: The extract was administered to the diabetic models for 30days. Findings: The extract produced a significant (p<0.05) dose-dependent decrease in the levels of total cholesterol (TC), Triacylglycerol (TG), low-density lipoprotein-cholesterol (LDL cholesterol), with a significant increase in the level High-density lipoprotein-cholesterol (HDL-C). Conclusion: The extracts of Capparis decidua< prove to have a hypolipidemic potential.
Idiopathic Benign Hyper-CK-Emia
Authors:   Specialty Clinics, St. Alexius Medical Center, 900 East Broadway Avenue, Bismarck, ND 58501, North Dakota, Kaushik Prashant , Gonuguntla Anuradha ,   Center for Family Medicine, 515 East Broadway Avenue, Bismarck, ND 58501, North Dakota
Published: September 2023

It is not uncommon for a rheumatologist to get a request for evaluating a patient with persistent elevation of serum creatine (phospho) kinase (CK) level (hyper-CK-emia) especially if this laboratory abnormality is persistent. We present a descriptive analysis of 16 consecutive adult patients seen with a condition called idiopathic benign hyper-CK-emia at a tertiary care Rheumatology Clinic in Bismarck, North Dakota. This condition is well described in the medical literature but unfortunately is not recognized very often by the primary care physicians especially its benign course. A short review of literature is also presented. To the best of our knowledge this is the first such report on this condition from the state of North Dakota.
Endovascular Treatment of a Ruptured Splenic Artery Aneurysm using Amplatzer® Vascular Plug
Authors:   Department of Vascular Surgery, Queen Elizabeth Hospital, Gateshead, Bhattacharya Vish , Nice CA ,   Department of Interventional Radiology, Queen Elizabeth Hospital, Gateshead, Manian UD , Badri H , Coyne PE , Ashour HY ,   Department of Vascular Surgery, Queen Elizabeth Hospital, Gateshead
Published: September 2023

Splenic Artery Aneurysms are commonly detected incidentally and can present acutely as a source of intra-abdominal catastrophe. Management options include both surgical and endovascular repair. The role of endovascular repair in an haemodynamically stable acute rupture is undefined and the use of Amplatzer® Vascular Plug has not to our knowledge been reported.
Pneumococcal serotypes recovered from health children and their possible association with risk factor in Istanbul, Turkey
Authors:   Department of Pediatrics, GATA Medical Faculty, Istanbul, Turkey, Cekmez Ferhat , Ozyurt Mustafa ,   Department of Microbiology, GATA, Medical Faculty, Istanbul, Turkey, Karademir Ferhan , Tanju I.Asya , Meral Cihan , Pirgon Ozgur , Gocmen Ismail
Published: September 2023

Streptococcus pneumonia is an increasing problem worldwide and nasopharyngeal colonization plays an important role in pneumococcal infections. The aims of this study were to assess the nasopharyngeal colonization rate, investigate the risk factors for nasopharyngeal colonization with S. pneumonia, serogroup and penicillin susceptibility patterns of Streptococcus pneumoniae strains isolated from healthy children. A single swab was obtained over the nasopharyngeal walls of the 500 healthy children of which 25 (5 %) were found to be carriers. The carrier rate was significantly higher in the seven-nine years-old age group. Upper respiratory tract infection within the last month (OR=1.1, p>0.001), day-care attendance (OR=3.1, p: 0.02), and the presence of more than five people living in the house of the child (OR=0.2, p: 0.003) have been determined to be risk factors for S. pneumoniae carriage. The most prevalent serogroups in descending order were 9, 19, 23, 6, 10 and 18 and these are in accordance with conjugated pneumococcal vaccine (PCV7). No penicillin-resistant S. pneumoniae were obtained. Conclusion:after conjugated vaccine we have seen benefits of vaccine in especiallycolonization rate and penicillin-resistance.
Kinetic Spectrofluorometric Determination of Certain Calcium Channel Blockers via Oxidation with Cerium (IV) in Pharmaceutical Preparations
Authors:   Department of Analytical Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt, Belal F. , Walash M. I. , El-Enany N. , Abdelal A. A.
Published: September 2023

A simple and sensitive kinetic spectrofluorometric method was developed for the determination of some calcium channel blockers namely, verapamil hydrochloride, diltiazem hydrochloride, nicardipine hydrochloride and flunarizine. The method is based upon oxidation of the studied drugs with cerium (IV) ammonium sulphate in acidic medium. The fluorescence of the produced Ce (III) was measured at 365 nm after excitation at 255nm. The different experimental parameters affecting the development and stability of the reaction product were carefully studied and optimized. The fluorescence-concentration plots were rectilinear for all the studied compounds over the concentration range of 0.01 to 0.12 µg mL-1. The limits of detections for the studied compounds ranged from 2.93 × 10-3 to 0.012 µg mL-1 and limits of quantification from 9.76 × 10-3 to 0.04 µg mL-1 were obtained. The method was successfully applied to the analysis of commercial tablets. The results obtained were in good agreement with those obtained with reference methods.
Spectrofluorimetric Determination of Famotidine in Pharmaceutical Preparations and Biological Fluids through Ternary Complex Formation with Some Lanthanide Ions: Application to Stability Studies
Authors:   Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt, El-Enany N. , Walash M. I. , El-Brashy A. , Wahba M. E. K.
Published: September 2023

A simple, sensitive and specific method was developed for the determination of famotidine (FMT) in pharmaceutical preparations and biological fluids. The proposed method is based on ternary complex formation of famotidine (FMT) with EDTA and terbium chloride TbCl3 in acetate buffer of pH4. Alternatively, the complex is formed via the reaction with hexamine and either lanthanum chloride LaCl3, or cerous chloride CeCl3 in borate buffer of pH6.2 and 7.2 respectively. In all cases, the relative fluorescence intensity of the formed complexes was measured at 580 nm after excitation at 290 nm. The fluorescence intensity - concentration plots were rectilinear over the concentration range of 10-100, 5-70, and 5-60 ng/ml , with minimum quantification limits (LOQ) of 2.4, 2.2, and 5.2 ng/ml , and minimum limits of detection (LOD) of 0.79, 0.74, and 1.7 ng/ml upon using TbCl3, LaCl3, and CeCl3 respectively. The proposed method was applied successfully for the analysis of famotidine in dosage forms and in human plasma. The kinetics of both alkaline and oxidative induced degradation of the drug was studied using the proposed method. The apparent first order rate constant and half life time were calculated. A proposal of the reaction pathways is presented.
A Validated Method without Derivatization for the Determination of Gabapentin in Bulk, Pharmaceutical Formulation and Human Urine Samples
Authors:   Vardhman Chemtech Ltd, Nimbua, Dera Bassi, Mohali, Punjab, India, Gujral Rajinder Singh , Haque Sk Manirul
Published: September 2023

A rapid, sensitive and accurate high performance liquid chromatography with UV detection method was developed and validated for the quantification of gabapentin in bulk, pharmaceutical formulation and human urine samples. Most of the published methods for analysis of gabapentin used derivatization with reagent. The present paper however describes the analysis of gabapentin without any derivatization. The chromatographic separation was carried out on a Waters C18 5 µm column (150 mm × 4.6 mm) using a mixture of methanol - acetonitrile - potassium dihydrogen orthophosphate (pH5.2; 0.028 M) (25:10:65) as a mobile phase with UV detection at 210 nm.The method was linear over the range of 0.1-3.8 mg/ml of gabapentin. The within day and between day precision values are very good.
Development and Validation of Pregabalin in Bulk, Pharmaceutical Formulations and in Human Urine Samples by UV Spectrophotometry
Authors:   Vardhman Chemtech Limited, Nimbua, Dera Bassi, Mohali, Punjab, India, Gujral Rajinder Singh , Haque Sk Manirul , Shanker Prem
Published: September 2023

A simple and sensitive UV spectrophotometric method was developed and validated for the determination of pregabalin in bulk, pharmaceutical formulations and in human urine samples. The method was linear in the range of 0.5-5.0 µg/ml. There is no generally accepted method for the determination of pregabalin. The absorbance was measured at 210 nm. The method was validated with respect to accuracy, precision, specificity, ruggedness, and robustness, limit of detection and limit of quantitation. This method was used successfully for the quality assessment of five pregabalin drug products and in human urine samples with good precision and accuracy. This is found to be simple, specific, precise, accurate, reproducible and low cost UV Spectrophotometric method.
Thrombelastography Guides Transfusion Strategy
Authors:   Departments of Anesthesia, Gentofte Hospital and Rigshospitalet, University of Copenhagen, Denmark, Nielsen Henning Bay
Published: September 2023

During surgery for an abdominal aortic aneurysm, coagulation may be impaired and the use of thrombelastography (TEG) is described in six patients with a perioperative blood loss of 3L. During surgery blood products were infused but not platelets. When the patients were admitted to the intensive care unit, the TEG report demonstrated a lowered MA value indicating impaired function of platelets. The use of TEG may guide transfusion strategy.
Effect of Collagen Gel Structure on Fibroblast Phenotype
Authors: Grace Lim Hui Yi , Wah Tong Yen
Published: September 2023

The microenvironment has been shown to play an integral role in determining cell phenotype. However, the difficulties faced in accurately replicating structural features of the native microenvironment have hindered the progress towards creating suitable three-dimensional scaffolds for tissue engineering purposes. In this project, we incorporated PEG and PEG-diNHS into collagen gels to produce different structural features, allowing us to simulate a range of cell microenvironments. PEG resulted in aggregation of collagen fibrils producing a larger fiber diameter while PEG-diNHS acted as a cross-linker between fibrils creating smaller pore sizes. Based on confocal imaging data, L929 fibroblasts cultured on collagen-PEG gels were observed to have the highest levels of filamentous actin accompanied by an elongated morphology, in contrast to the rounded phenotype of fibroblasts from collagen-PEG-diNHS gels. These observations are a reflection of the in vivo wound healing process, in which changes in the ECM can induce fibroblasts to adopt different phenotypes that contribute to the recovery process.
Structural Phenomena of Talafri's Poetry in Light of Semantics
Authors: Obeidat Rijan
Published: September 2023

This study deals with the structural Phenomena of Talafri's poetry that formed one of the most prominent stylistic features in his language in terms of its shift from the normal, this is because poetry is a transcendent linguistic act in its formation and methods of formulation, in the extent of the displacement through which the text poeticity deepens or flattens, and in the space of transcendence lies the poet’s craftsmanship. The aesthetics of the expressive language is shown through the stylistic techniques it uses, as well as the stylistic phenomena it produces and which form individual creative imprints that distinguish the poet.
The Impact of Practicing Social Intelligence in Enhancing Organizational Excellence: A Case Study in the Jordanian Civil Status and Passports Department
Authors: Al-Hawatmeh Salah , Al-Mahasneh Mohamed
Published: September 2023

The study aimed to reveal the impact of the practice of social intelligence on organizational excellence in the Jordanian Department of Status and Passports. The study population consisted of all senior and middle leaderships,  and the study relied on a comprehensive survey of (350)  respondents to collect data. After conducting the analysis of the study data and its hypotheses، the study concluded that there is a statistically significant effect of social intelligence in its dimensions on organizational excellence. The study recommended promoting organizational excellence and linking it with excellence, goals and performance  results on the short and long terms, as well as expanding the use of information technology and electronic transformation  to maintain its ability to reinforce organizational excellence.
Analisis Tingkat Kesehatan Perusahaan dari Aspek Keuangan Berdasarkan Keputusan Menteri BUMN Nomor: KEP-100/MBU/2002
Authors: Meri Dita Rahayu  , Indah Listyani  , Edi Murdiyanto
Published: September 2023

This research aims to determine the level of company health from a financial aspect based on the Decree of the Minister of BUMN Number: KEP-100/MBU/2002 at PT. Krakatau Steel (Persero) Tbk for the 2017-2021 period. The method used in this research is quantitative descriptive. This health level assessment uses 8 financial aspect indicators, namely ROE, ROI, Cash Ratio, Current Ratio, Collection Periods, Inventory Turnover, Total Asset Turn Over, and Total Own Capital to Total Assets. Based on the research results, PT. Krakatau Steel (Persero) Tbk for the 2017-2021 period experienced increases and decreases as seen from 8 financial ratio indicators. The financial health assessment in 2017 and 2018 was in the unhealthy predicate in the BBB category with a final score of 55 in 2017 and 53.21 in 2018, however in 2019 it was in the unhealthy predicate in the CCC category with a final score of 30, whereas in 2020 it was ranked as unhealthy in the BB category with a final score of 47.14 and in 2021 it was ranked as unhealthy in the BBB category with a final score of 55. So it can be concluded that the financial health of PT. Krakatau Steel (Persero) Tbk is in an unhealthy condition.
Analisis Kinerja Keuangan Dengan Menggunakan Perhitungan Gross Profit Margin (GPM), Net Profit Margin (NPM) Dan Return On Equity (ROE) Pada Pt. Pakuwon Jati Tbk Periode 2018-2021
Authors: Binti Umaya  , Indah Listyani  , Edi Murdiyanto
Published: September 2023

A company needs to pay attention to financial performance in order to see how far the company's position by analyzing financial statements. This study aims to determine the financial performance of PT. Pakuwon Jati Tbk in 2018-2021 using the ratio of Gross profit Margin, Net Profit Margin and Return on assets. This type of research is descriptive with quantitative data taken secondarily from the balance sheet and income statement of PT. Pakuwon Jati Tbk for 2018-2021. Samples were taken from the population according to the saturated sampling method. The results of research that has been done show that the financial performance of GPM and NPM are in a good state that is above the industry average standard, GPM shows a decline while NPM shows unstable fluctuations. The results of financial performance with ROE in poor condition because it is below the industry average standard with fluctuations that are also unstable.
The Influence of Football Player Endorsement on Company Credibility, Ad Credibility, and Brand Credibility at East Hooligan Apparel Store
Authors: Setiawan Thomi Yasri , Rostika Raden Roro Ratna
Published: September 2023

This research aims to examine and analyze the effect of celebrity trust with the use of endorsed football players on company credibility, advertising credibility, and brand credibility at the East Hooligan Apparel store. Model and hypothesis testing were clear using a sample of 250 respondents with a population of consumers who were interested in the use of football attributes such as jersey, shirt, jacket, and others. The sampling technique used was purposive sampling. The Structural Equation Modeling (SEM) method was developed to test the research hypothesis which was processed using Partial Least Square (PLS) version 3.0. The data variables used in this case include celebrity trust, company credibility, advertising credibility and brand credibility. These variables form 6 hypotheses. Based on the results of the study, it is known that celebrity trust has a positive effect on advertising credibility, company credibility, and brand credibility. In addition, advertising credibility has a positive effect on company credibility and also brand trust has a positive effect on advertising credibility and company credibility.
Factores y consecuencias que inciden en la deserción escolar: una perspectiva sociológica
Authors:   Escuela de Ciencias de la Educación, Hernández Moreno Héctor Azael
Published: September 2023

La deserción escolar se encuentra inmersa dentro de los sistemas sociales de cada país como también está presente en México y es una problemática que desemboca con repercusiones dentro de la vida cotidiana a través de problemas sociales como: dreamers, migración, robos, delincuencia, narcotráfico, ninis, entre otros. De ahí la importancia de comprender el problema desde un panorama científico con el fin, de poder generar contribuciones que aminoren la problemática antes mencionada desde las contribuciones sociales pero también, lograr entender la manera en que incide la problemática dentro del plano de cada individuo. Por ello en el presente documento se pretende evidenciar los factores que inciden en la deserción escolar desde el plano Internacional, Nacional y/o Estatal, con el fin de concluir presentando una teoría del fenómeno de la deserción escolar la cual, se estructura con base en un conjunto de enunciados interrelacionados que definen, describen, relacionan y explican fenómenos de interés.
Relación entre el horario de comidas, la composición corporal y pérdida de peso
Authors: Anaya Perez Carlota
Published: September 2023

El aumento de peso entre la población mundial es un tema relevante en estos últimos años. Abordajes nutricionales que tengan en cuenta los horarios de las comidas, así como su frecuencia pueden ser interesantes a la hora de mejorar la composición corporal de la población y el peso. El objetivo es conocer si existe relación entre el número y el horario de las comidas, la composición corporal y la pérdida de peso. Se realizó una revisión bibliográfica, fueron seleccionados y consultados artículos científicos, tanto estudios como revisiones, webs oficiales y documentos relevantes. Se tuvieron en cuenta un total de 12 estudios publicados en los últimos 5 años pertenecientes a la base de datos Pubmed y Scielo, los cuales fueron analizados en profundidad. Además, se empleó el uso del buscador de Google para páginas oficiales, Tanto el horario de las comidas como la frecuencia en la que estas se realizan o los macronutrientes que ingieren son estrategias dietético-nutricionales efectivas para la modificación de la composición corporal y del peso. Se necesitan un mayor número de investigaciones actuales, sobre todo en el ámbito de la frecuencia de las comidas para demostrar los efectos sobre la composición corporal, sin embargo, se puede concluir que tanto tener en cuenta los macronutrientes que se ingieren como el timing alimentario, son posibles estrategias de abordaje nutricional competentes para el cambio de composición y peso corporal.
Efecto de la Dieta Mediterránea en la prevención de la preeclampsia
Authors: Lasarte García Álvaro
Published: September 2023

La preeclampsia es una complicación con una prevalencia notoria hoy en día que podría ser prevenida mediante un estilo de vida saludable, en este caso, con una dieta mediterránea.Demostrar si de verdad una dieta mediterránea adecuada consigue mejorar el estado de salud materno, en concreto, la preeclampsia. Material y métodos: Se realizó una revisión bibliográfica. Se utilizaron 89 referencias bibliográficas, utilizando 23 artículos sacados de Medline, Pubmed y Scielo para la discusión de estos conceptos, estudiando 15 de estos en profundidad.  La mayoría de estudios discutidos fomentan el uso de la dieta mediterránea para evitar complicaciones en el embarazo, aunque la gran parte de ellos con numerosas limitaciones. El papel de los ácidos grasos omega 3, o algunos micronutrientes como el calcio, fósforo y vitamina D sí que tienen una alta evidencia de beneficios en la prevención de las complicaciones en el embarazo. Conclusiones: La dieta mediterránea parece tener características idóneas para la salud, pudiéndose recomendar a las gestantes para evitar la preeclampsia y otras complicaciones. Aun así, se requiere más investigación. Lo que se tiene claro es la importancia de una alimentación variada y equilibrada.
Penyusunan Rencana Pembangunan Desa Berdasarkan Data Sarana Dan Prasarana Dalam Sistem Informasi Desa Pada Desa Teratak, Kec. Rumbio Jaya, Kab. Kampar, Provinsi Riau
Authors: Daffeta Fitrilinda  , Fitra Herlinda  , Mahmu Datu Rahma  , Dwi Joyandanila  , Dzaskhia Delvani Putri  , Elvira Zahera  , Haziq Hidayatullah  , Firdah Mahirah  , Windi Oktavia  , Feris Adek Subagia  , Raja Ardika
Published: September 2023

Village development plan preparation activies are carried out using a database that is already in the SID. Some of the data that will be used is village facilities and indrastructure data. The aim of this years PKM activity is to Provide Guidance to village government officials in preparing village development plans based on village facilities and infrastructure data in the SID. The method that will be used by the PKM team will be carried out in two stages of activity. This stage of activity begins with the preparation stage and then continues with the implementation stage. Preparation stage activities include: Coordination with village Apparatus, division of colloborative tasks with village apparatus and PKM team, collection and grouping of digital and non digital data, compilation of facilities and infrasrtucture data in SID. Meanwhile the activity implementaion stages include.: Evaluation of the previous RPJMDes, formation of the drafting tea, meeting of the drafting team in the context of aglining develpment policy direction, preparation of planning and design of the RPJMDes, determination of the RPJMDes. The impact of this activity is (1) The village has a village development planning document refeering to the complete, accurate and up to date condition of village facilities and infrastructure via SID. (2) The village has village government officials who are skilled at managing the village information system and utilizing it to improve community contributes to the preparation of village development planning by providding information directly through SID.
Appeal for People's Power: Legal Perspectives In The 2019 Presidential And Vice-Presidential General Elections
Authors: Riyady Slamet
Published: September 2023

On April 17, 2019, Indonesia conducted a simultaneous general election involving five ballots for various political offices. The objective was to reduce election costs and improve efficiency. Despite a well-established electoral system, certain political elites contested the results using calls for 'people power.' This research aims to examine the legal implications of such calls and their compatibility with the law. Using a normative approach and legal behavior case studies, this study utilizes primary data from laws and secondary sources, such as books on democracy and freedom of expression. The theoretical contribution lies in clarifying that freedom of expression should not be considered seditious, as sedition entails efforts to overthrow the government. However, if demonstrators violate regulations, particularly Article 6 of the Freedom of Expression Law, it may be considered sedition. It is recommended to handle the results of the presidential and vice-presidential elections maturely by entrusting them to the competent authority, the Constitutional Court.
The Validity of Informed Refusal With Elements of Forced Discharge of COVID-19 Patients From Hospitals, as Reviewed in Accordance With Law No. 29 of 2004 on Medical Practices, in Conjunction With Law No. 4 of 1984 on the Prevention of Infectious Diseases
Authors: Purwanto Agus
Published: September 2023

Health is a vital aspect of human life. Covid-19 has had a significant impact on the Indonesian population, particularly on their health. During this period, the healthcare profession has come under intense scrutiny due to its direct involvement in healthcare. In the management of the Covid-19 pandemic, challenges have arisen, notably the high number of patients or their families requesting forced discharge before recovery. The research problem and objectives revolve around the validity of informed refusal with elements of forced discharge at the request of Covid-19 patients from hospitals and the legal consequences for both patients and doctors. The research methodology employed is empirical juridical, with primary data collected through questionnaires at a private hospital in West Jakarta, complemented by references from various sources, including books, journals, and legal regulations. Data analysis was conducted using a qualitative normative approach. The research findings indicate that cases of forced discharge following a Covid-19 diagnosis persist despite the existence of regulations such as the Health Law and the Law on the Prevention of Infectious Diseases. In conclusion, informed refusal does not constitute an agreement but rather a unilateral statement by the patient to the hospital and/or doctor. Consequently, full responsibility lies with the patient, as there are currently no regulatory provisions or prohibitions allowing patients to voluntarily leave the hospital, even if the patient's condition has not been assessed as fully recovered by the hospital or doctor.
Application of the system of potential landevaluation of agricultural land in production practices
Authors:   Agricultural Academy, ISSAPP “N. Pushkarov”, Sofia, Radovanova Ivelina
Published: September 2023

The study clearly presents the positive effect of the application of the newly developed “Methodology for the Potential Assessment of Agricultural Lands in Bulgaria” (Radovanova, 2022) and the corresponding software (Radovanova, 2023), simultaneously with the existing “Methodology for the Current Assessment,”, in agricultural production practices. The object of research is agricultural land with alluvial-meadow soil above the floodplain terraces of the Iskar River in the Samokov field. In parallel, Land Evaluation was carried out through two approaches: 1. Actual Evaluation and 2. Potential Evaluation. It has been established that 2 crops are economically profitable to grow - potatoes and wheat.According to the individual ratings (minimum actual and maximum potential) of the characteristics of this land and the corresponding Field Ratings, guidelines are given for optimizing cultivation technologies and recommending triple crop rotation.
Impact of advanced soil conservation technologies for growing maize on sloping terrains on soil microbiota
Authors:   Agricultural Academy, Institute of Agriculture and Seed Science “Obraztsov Chiflik” - Rousse, Ivanova Iliana , Kuncheva Gergana ,   Agricultural Academy, Institute of Soil Science, Agrotechnology and Plant Protection “N. Poushkarov”, Sofia
Published: September 2023

Water erosion leads to the loss of soil, nutrients, organic matter, disruption of soil structure, reduction of moisture capacity, loss of biodiversity, and is the most significant soil degradation process when growing agricultural crops on sloping terrain. Soil microorganisms are the basis of the functioning of ecosystems, the circulation of substances, soil-forming processes and the formation of the soil structure. Microbiological indicators, such as numbers, microbial biomass, enzyme activity, etc., are a sensitive indicator of the changes that have occurred in the soil, under the influence of anthropogenic or natural impacts. The present study is on the abundance of major groups of soil microorganisms, when applying different tillage systems in growing maize on sloping terrain. The study was carried out on Carbonate Black Earth, at the Experimental Station for Combating Soil Erosion, at IASSPP “N. Pushkarov”, in the village of Trastenik, Ruse, Agricultural Academy - Sofia. A field experience with corn for grain, applying traditional and anti-erosion technologies (surface and vertical mulching) for growing corn, is presented. The obtained results show a positive influence of the applied soil protection technologies on the number of saprophytic bacteria, mold fungi, actinomycetes, nitrogen-fixing and cellulose-degrading microorganisms.
Breeding skuas in Orkney: a 2010 census indicates density-dependent population change driven by both food supply and predation
Authors: Meek E. , Bolton M , Fox D , Remp J
Published: September 2023

Great Skuas Stercorarius skua and Arctic Skuas S. parasiticus were counted on their breeding grounds in Orkney during June 2010. Great Skua numbers had fallen by 23% overall since the previous census in 2000. However, the decline was not uniform across Orkney, the major colony on Hoy declining by 32% but with many smaller colonies actually increasing. Possible reasons for this difference are discussed. Arctic Skua numbers fell by 47% in the same time period and by 64% from their peak in 1992. We found evidence of intra-specific negative density dependence in trends of both skua species, suggesting that declines may have been driven by low food availability. In addition, we found a negative relationship between Arctic Skua trends between 2000 and 2010 and the numbers of Great Skuas present in each colony in 2000. These findings suggest that whilst scarcity of food may have contributed to Arctic Skua declines, predation by Great Skuas is likely to have played an additional role. Predation on Arctic Skuas, both adults and young, is also likely to be ultimately attributable to a scarcity of alternative fish prey for Great Skuas.
An unprecedented Western Palearctic concentration of Wilson’s Storm-petrels Oceanites oceanicus at an oceanic upwelling front offshore Mauritania
Authors: Wynn Russel , Krastel Sebastian
Published: September 2023

An opportunistic boat-based survey to the Mauritania upwelling zone in July 2005 discovered an unprecedented concentration of Wilson’s Storm-petrels Oceanites oceanicus. Flocks of up to 600 birds were concentrated along the boundary between warm surface waters and cooler upwelled waters. These flocks formed an aggregation of at least 5,000 birds, which is an unprecedented total for this species in Western Palearctic waters.