bluuebunny/crossref_metadata_2025 huggingface dataset:
«Læreren snakker i en evighet»: Vilkår for elevdeltakelse og faglig dialog på mellomtrinnet – slik elevene ser det
Authors: Jensen Ingeborg Maria , Wagner Åse Kari Hansen
Published: November 2024

Elevdeltakelse og muntlig aktivitet som vilkår for dybdelæring står sentralt i de siste årenes revisjoner av læreplanene. Forskning på dialog og elevdeltakelse kan være avgjørende bidrag til utviklingen av praksisfeltet. Eksisterende forskning har i stor grad et lærerperspektiv, og det er få studier som utdyper hvordan de eldre barneskoleelevene erfarer vilkår for dialog og deltakelse, særlig i de fire sentrale fagene som diskuteres i denne studien. Vi adresserer dette forskningsgapet ved å utforske hvordan elever på sjette og sjuende trinn reflekterer om faglig praksis i fire fag i skolen, og hvilke muligheter de har for dialog og deltakelse i undervisningen. Elevene erfarer at mye av skoledagen går med til å lytte til læreren og gjøre oppgaver, mens det er mindre av utforskende aktiviteter, refleksjon og argumentasjon. Studien demonstrerer også hvordan nyskapende intervjumetoder kan åpne opp for elevenes evne til å reflektere over eksisterende praksis og alternative praksisformer.
 
English abstract
“The Teacher Talks Forever”: Conditions for Student Participation and Academic Dialogue in Upper Elementary School – From the Students’ Perspective
Student participation and oral activity as conditions for deep learning have been central to recent curriculum revisions. Research on dialogue and student participation can provide crucial insights for developing educational practices. Existing research has largely focused on the teacher’s perspective, with few studies delving into how older elementary school students experience the conditions for dialogue and participation, particularly in the four core subjects discussed in this study. We address this research gap by exploring how students in the Norwegian sixth and seventh grades reflect on academic practices in four school subjects and the opportunities they have for dialogue and participation in the classroom. Students report that much of the school day is spent listening to the teacher and completing tasks, with less emphasis on exploratory activities, reflection, and argumentation. This study also demonstrates how innovative interview methods can unlock students’ ability to reflect on both current practices and alternative forms of practice.
Ventricular-arterial Coupling: Advances and Current Perspectives in Cardiovascular Research
Authors: Toktarbay Bauyrzhan , Zhankorazova Aizhan , Khamitova Zaukiya , Jumadilova Dinara , Salustri Alessandro
Published: November 2024

The concept of ventricular-arterial coupling (VAC) was first introduced in the early 1980s to quantify the relationship between left ventricular contractility and arterial load. The mathematical formulation of VAC, expressed as the ratio of arterial elastance to ventricular elastance, has since then been refined with adjustments to allow for non-invasive assessment. By the early 2000s, advancements in echocardiography, cardiac magnetic resonance and arterial tonometry provided non-invasive alternatives to the traditional invasive method of cardiac catheterization, broadening the clinical application of VAC. Emerging technologies, such as machine learning and computational models, have further enhanced the precision and personalization of VAC, with potential applications in heart failure, hypertension and other clinical scenarios.

This review describes the physiological basis and the historical development of VAC, highlights the non-invasive assessment techniques, and discusses the potential for personalized treatment based on VAC insights. Machine learning models trained on large datasets from non-invasive imaging modalities may open new avenues in predicting individual patient responses to therapies. However, lack of standardized protocols across imaging modalities represents a challenge, making the call for standardization critical for consistent clinical application. This review underscores the need for harmonized methodologies to better utilize VAC in personalized medicine, aiming to improve cardiovascular outcomes through tailored therapies.
Genetic portraits of Khanty and Mansi based on the Y chromosome haplogroups in the context of gene pools of Russia
Authors: Ponomarev GYu , Agdzhoyan AT , Potanina AYu , Adamov DS , Balanovska EV
Published: November 2024

Khanty and Mansi are small indigenous peoples of Western Siberia with the unique cultural, anthropological, and linguistic characteristics. The study of their gene pool will make it possible to reconstruct the genetic structure of the Ugric-speaking population, of which in modern times only Khanty and Mansi remain, along with Hungarians, in whose gene pool there are traces of medieval migration of the Ugric-speaking Magyars. The detailed characterization of the gene pool of Khanty and Mansi is important for reconstruction of Ugric populations and genetic history of the region. The study was aimed to assess representative samples of Khants (n = 83) and Mansi (n = 74) based on the standard panel of 60 SNP markers and the extended panel of 74 Y-chromosomal SNP markers by statistical and cartographic methods in the context of indigenous population of Urals and Western Siberia. The differences between the gene pools of Khanty and Mansi have been revealed based on both standard panel of Y chromosome haplogroups and branches of haplogroups N2 and N3a4. Most of the Khanty gene pool is evenly distributed between N2-Y3195 (26%), N2-VL67 (23%), and N3a4-Z1936 (23%). The “Western” branch N2-Y3195 predominates in the Mansi gene pool (69%). Mansi gravitate towards populations of the Urals-Volga region in the multidimensional genetic space. Based on the standard panel of Y haplogroups, Khanty are close to the populations of Western and South Siberia. However, the analysis of branches N3a4 has shown that Khanty are intermediate between the “Uralic” and “Siberian” clusters: when the ancestors of Khanty moved from the Ural region to the northeast, these acquired both genetic components. The gene geographic maps of 10 haplogroup N3a4 branches in the populations of Urals and Western Siberia reflect the dynamic changes of the gene pool that took place 4–2 kya.
Novyj rekombinantnyj ingibitor RNKaz LoRI dlya primeneniya in vitro
Authors: Сухов Д. А. , Холошенко И. В. , Петрова Т. В. , Романенко Г. А. , Мышкин М. Ю. , Кост В. Ю. , Трофимов Д. Ю. , Усман Н. Ю. , Барсова Е. В.
Published: November 2024

Ingibitory RNKazy davno ispol'zuyut v biotekhnologii i laboratornoj diagnostike. Cel'yu raboty bylo poluchit' i oharakterizovat' novyj rekombinantnyj ingibitor RNKaz LoRI. Poluchennyj novyj ingibitor ribonukleaz LoRI predstavlyaet soboj rekombinantnyj belok massoj 63 kDa, optimizirovannyj dlya vysokoproizvoditel'noj ekspressii v E. coli i ochistki s pomoshch'yu metallohelatnoj affinnoj hromatografii (IMAC). Produkt poluchen za schet N-koncevogo sliyaniya polipeptidnoj posledovatel'nosti placentarnogo ingibitora RNKaz myshi s tioredoksinovym modulem. Celesoobraznost' dannoj modifikacii s tochki zreniya struktury i funkcii belka podtverzhdena in silico. Vyhod ochishchennogo rastvorimogo rekombinantnogo produkta v laboratornyh usloviyah sostavil okolo 12 mg na 1 l ekspressionnoj bakterial'noj kul'tury. Po aktivnosti in vitro produkt sopostavim s kommercheskim analogom ili prevoskhodit ego. Kineticheskie dannye sootvetstvuyut modeli Lajnuivera–Berka.
Билогистическая аппроксимация функций мощности перколяционных кластеров на ограниченных неравномерно взвешенных квадратных решетках с (1, 0)-окрестностью
Authors: Москалев Павел , Мягков Александр
Published: November 2024

Проводится анализ модели, используемой для аппроксимации функций мощности перколяционных кластеров на ограниченных квадратных решетках с (1, 0)-окрестностью, взвешенных бета-распределенными случайными величинами. Аппроксимация строится как произведение функции взвешивающего распределения и пары двухпараметрических логистических функций. Статистические оценки параметров моделей получены с помощью нелинейного метода наименьших квадратов. Показано, что апостериорные оценки сдвиговых параметров обеих логистических функций значимо отличаются от априорных оценок порога перколяции, что приводит к существенной асимметрии функции, аппроксимирующей мощность перколяционных кластеров на ограниченных квадратных решетках с (1, 0)-окрестностью.
PROFESSIONALLY ORIENTED SCIENTIFIC AND RESEARCH ACTIVITY OF STUDENTS AS AN IMPORTANT COMPONENT OF COMPETENT SPECIALIST TRAINING
Authors: Lohvynenko Tetyana , Varga Nataliya , Popyk Mariana
Published: November 2024

The issue of the development of research skills and the organization of research activities of students of higher education institutions is multifaceted. Currently, one of the leading global trends in university education is the integration of the research component into the process of training of future specialists. The purpose of the article: to consider the features of professionally oriented scientific and research activity of students. Research methods applied: theoretical analysis of scientific sources on the issue of scientific and research work as an important component of the training of higher education institutions students; critical and analytical analysis of concepts, theories, and methods. Professionally oriented research work includes observation, study of facts and phenomena of professional reality; awareness of professional issues, their analysis; developing a goal and setting tasks; proposing hypotheses, choosing research methods; theoretical problem solving; and evaluation of the obtained results by the goals set. The main functions of professionally oriented research activity are: social; intersocial; systemic; integrative; modeling; information; communicative; technological; motivational; developmental; and reflexive. The outlined content of the functions of the research activity allows us to distinguish and analyze certain personal qualities, as well as several research and professional knowledge, abilities, and skills. An important component of research activities is an emotional attitude to the R&D. The search for approaches to solving the task is additionally regulated by emotional assessments that are formed as a result of the task and can change repeatedly. Awareness of future professional activity is decisive: the activity of students in scientific research depends on how they imagine their profession and whether they consider the skills of research work as a component of specialist competence. A necessary quality of researchers is sociability and independence.
MASTERING SWIMMING AND TECHNICAL SKILLS IN THE FRAMEWORK OF INITIAL WATER POLO TRAINING
Authors: Mordvintsev Gennady , Petrushko Maryna
Published: November 2024

The purpose of the article is to consider the content and sequence of acquisition of swimming and technical skills by children and adolescents as part of initial water polo training, to provide relevant methodological recommendations to children’s coaches. Methods applied: analysis of scientific sources, pedagogical observation, generalization of coaching experience, synthesis of empirical information, classification and typology, and comparison. The article describes water polo swimming styles and some specific techniques of initial swimming training, including Head-Up Freestyle and Head-Up Backstroke, Trudgen and Sidestroke, swimming in place and walking in the water using various techniques such as Eggbeater Kick, Sculling or Breaststroke Kick, lifting and holding the body above the water and jumping out of the water, start for performing a dash, stopping, turning, and lunging. After mastering swimming skills, the initial training focuses on the technique of working with the ball. It is necessary to study the technical elements of water polo in compliance with the basic didactic principles, in a clear sequence of learning techniques from easier to more difficult. The author recommends switching to technical training no earlier than 10 years of age and devoting 2-3 years to mastering technical techniques. In the process of technical training, young water polo players consistently learn the techniques of picking up the ball from the water in different ways, dribbling the ball, catching it, transferring the ball from one hand to other, different types of Shooting for passing. Exercises for mastering the technical skills of water polo should be selected and used methodically competently. It is desirable to perform some of them first on land, and only then in water, first without movement, and only then in motion, so that the conditions for performing the exercises gradually approach those of the game. To make water polo training more interesting and attractive for children, the author recommends using Splashball as a modified version of water polo for beginners.
REFLECTION IN THE STRUCTURE OF INNOVATIVE COMPETENCE OF TEACHERS IN GENERAL SECONDARY EDUCATION INSTITUTIONS
Authors: Oliynyk Oksana
Published: November 2024

The issue of the article concerns the topical issue of innovative competence and its components. The author aimed to characterize one of the components of this education, which refers to the ability to analyze the effectiveness and efficiency of pedagogical activity, as well as to adjust it as necessary. It is about the skill of reflection as one of the leading features of a teacher with highly developed innovative competence, since the creation and implementation of innovations requires regular analysis not only of the process of implementing something new in the educational process but also of observing and evaluating the personality of the teacher as a specialist who carries out innovative activities. Thanks to the use of such methods of scientific research as system-structural and system-functional analysis, generalization and systematization of theoretical aspects of the topic, observation, and study of the products of pedagogical activity, the author conducted a review of scientific literature regarding the essence of innovative competence of a teacher of a general secondary education institution, its structure and key characteristics, in particular, reflection skills. In addition, the publication provides information on reflective competence, which, on the same level as innovative competence, occupies a prominent place in the system of professional characteristics of a teacher regulated by normative documents. The unifying feature for both is the skill of reflection, therefore the article also presents the views of domestic scientists on the essence of this phenomenon and methods of its development and improvement. In addition, practical tools (reflective questionnaires, tables; reflective essays; pedagogical portfolios, etc.) are characterized, which contribute to the formation and improvement of the ability to reflect on one's pedagogical activity, in particular innovative ones. The publication analyzes fragments of reflective essays from teachers of general secondary education institutions who took the experimental course "Innovative aspects of the teacher's activity". This made it possible to conclude the reflexive competence of teachers, the development of reflection skills, as well as to substantiate reflection as a component of innovative competence.
Assessing the potential impact of an oral health education package integrated with augmented reality in improving oral health knowledge in children: a pre-post study design.
Authors: Rahmasari Suci , Arini Mustika , Khairani Rahmi
Published: November 2024

ABSTRACTIntroduction: Augmented reality (AR) technology provides a novel approach to oral health education. This study examines the impact of AR-based educational tools on improving children's oral health knowledge, specifically assessing whether AR can significantly enhance knowledge compared to baseline. The primary objective is to determine if AR technology can increase oral health knowledge in children. Methods: This pre-experimental study used a pre-test and post-test design with a single group of 49 children aged 7 years. The AR-based tool was developed using the ADDIE model and implemented over two weeks. The effectiveness of the tool was assessed through a standardized oral health knowledge questionnaire, and data were analyzed using paired t-tests. Results: The results showed a significant increase in children's knowledge after the intervention, with mean scores rising from 5.27 (SD = 1.36) to 8.65 (SD = 0.9) (p < 0.05). The proportion of children with good knowledge increased from 8.2% to 88% post-intervention. Conclusion: The study demonstrates that AR-based tools can significantly improve children's oral health knowledge. This suggests that AR could be an effective educational medium in promoting better oral health practices among young learners.
Manifestaciones de microagresiones raciales en la educación bibliotecaria: enfoque en el trauma racial
Authors: Silva Franciéle Carneiro Garcês da , Garcez Dirnéle Carneiro , Romeiro Nathália Lima , Fevrier Priscila Rufino , Alves Ana Paula Meneses , Souza Miriely da Silva
Published: November 2024

Este estudio investiga manifestaciones de microagresiones raciales, con énfasis en medir el trauma racial experimentado por estudiantes negros matriculados en cursos de biblioteconomía. El objetivo general es comprender cómo se manifiestan las microagresiones raciales en este contexto. Los objetivos específicos incluyen: 1) definición conceptual de microagresiones raciales y sus características; 2) categorización de las formas en que estas microagresiones se manifiestan en las interacciones; 3) aplicación de la Escala de Microagresión Racial en la Enseñanza de la Biblioteconomía (EMREB). Desde el punto de vista metodológico, se trata de una investigación aplicada, cualitativa, que utiliza métodos documentales, bibliográficos, exploratorios y descriptivos. El estudio se divide en tres fases: 1) revisión de la literatura; 2) aplicación de cuestionarios y análisis de resultados; 3) desarrollo y aplicación de la escala. El análisis y aplicación de la escala revelan la presencia de microagresiones, que se manifiestan a través de prácticas sutiles, mensajes verbales y no verbales llenos de desprecio, sexismo y racismo, perpetuados por profesores y colegas blancos en el ámbito de la clase. Las microagresiones más frecuentes caen en las categorías de Deslegitimación/Invalidación y Amenaza/Intimidación, y las formas de opresión se cruzan con la opresión de género, racial y sexual en la experiencia educativa de los estudiantes negros en la educación superior. Con la escala, se encontró que las microagresiones raciales tienen consecuencias traumáticas y, junto con las categorías de opresión observadas, tienen un impacto duradero en la vida de los estudiantes negros observados.
Servicios de referencia como herramientas anti crisis: el caso de la Biblioteca de la Facultad de Humanidades y Ciencias de la Educación de la Universidad Nacional de La Plata (BIBHUMA) entre los años 2019 y 2022
Authors: Quinteros Felipe
Published: November 2024

El siguiente trabajo tiene como objetivo general demostrar, mediante el caso testigo de la actividad del Servicio de Referencia de la Biblioteca de la Facultad de Humanidades y Ciencias de la Educación de la Universidad Nacional de La Plata, de qué manera una buena praxis y gestión del mismo puede apoyar a una institución bibliotecaria en una situación de crisis. Para esto se emplearán los datos estadísticos de uso del servicio de los años 2017 al 2023 y se someterán a comparación cuantitativa y cualitativa. Se argumenta que entre los aspectos que contribuyeron a sostener y acrecentar el Servicio de Referencia durante la crisis sanitaria mundial del COVID-19 se encuentran las decisiones de gestión y la buena respuesta del personal.
Nowa era trombokardiologii, czyli naczyniowa dawka riwaroksabanu w leczeniu przeciwzakrzepowym chorób miażdżycowych. Dlaczego, kiedy i u kogo?
Authors: Barylski Marcin
Published: November 2024

Na konieczność poprawy skuteczności terapii przeciwzakrzepowej w prewencji wtórnej wskazuje fakt, że intensywne leczenie przeciwpłytkowe tylko częściowo obniża ryzyko sercowo-naczyniowe. Wyniki badania COMPASS dostarczyły dowodów na to, że dodatkowe zablokowanie wybranych pięter kaskady krzepnięcia może istotnie wpłynąć na dalszą prewencję poważnych zdarzeń sercowo-naczyniowych w wybranej grupie chorych. Aktualne wytyczne Europejskiego Towarzystwa Kardiologicznego niezmiennie podkreślają wysoką pozycję naczyniowej dawki riwaroksabanu w połączeniu z kwasem acetylosalicylowym, co jest niewątpliwie nie tylko pokłosiem doskonałych wyników badania COMPASS, ale również stanowi niezwykle ważny element nowoczesnego i kompleksowego leczenia, ukierunkowanego na jak największą redukcję ryzyka incydentów sercowo-naczyniowych.
Latanoprost drops without added detergent in the treatment of glaucoma
Authors: Misiuk-Hojło Marta , Mimier-Janczak Małgorzata , Łątkowska Małgorzata
Published: November 2024

Chronic nature of both the disease and its therapy forces ophthalmologists to choose the treatment with the lowest potential for adverse reactions, which may be caused by the active substance, excipient or preservative. Detergents used in ophthalmic drops include a derivative of macrogolglycerol hydroxystearate-40 (MGHS-40), which in in vitro tests showed pro-inflammatory and cytotoxic properties towards corneal epithelial cells, and this effect increased with increasing concentration and time. The analyzed observational study showed that latanoprost without MGHS-40 effectively reduces intraocular pressure, and the factors encouraging ophthalmologists to choose this preparation were good local tolerance and a simple composition (without detergents, preservatives and antioxidants), improving compliance. In the observational study, 82.3% received latanoprost without MGHS-40, and almost 60% started antiglaucoma treatment with this preparation.
Leveraging metaphors in qualitative machine translators in the interpretation of emotion
Authors: Xiao Guannan , Fan Pikshy
Published: November 2024

The idea of emotions that is concealed in human language gives rise to metaphor. It is challenging to compute and develop a framework for emotions in people because of its detachment and diversity. Nonetheless, machine translation heavily relies on the modeling and computation of emotions. When emotion metaphors are calculated into machine translation, the language is significantly more colorful and satisfies translating criteria such as truthfulness, creativity and beauty. Emotional metaphor computation often uses artificial intelligence (AI) and the detection of patterns and it needs massive, superior samples in the emotion metaphor collection. To facilitate data-driven emotion metaphor processing through machine translation, the study constructs a bi-lingual database in both Chinese and English that contains extensive emotion metaphors. The fundamental steps involved in generating the emotion metaphor collection are demonstrated, comprising the basis of theory, design concepts, acquiring data, annotating information and index management. This study examines how well the emotion metaphor corpus functions in machine translation by proposing and testing a novel earthworm swarm-tunsed recurrent network (ES-RN) architecture in a Python tool. Additionally, the comparison study is carried out using machine translation datasets that already exist. The findings of this study demonstrated that emotion metaphors might be expressed in machine translation using the emotion metaphor database developed in this research.
Interconnectedness of financial markets in crises in the case of the enlarged BRICS
Authors: Romashkina Gulnara , Andrianov Kirill , Skripnuk Djamilia , Yukhtanova Yulia
Published: November 2024

The article presents a study of the connectivity and integration of sovereign bond and stock markets in 10 BRICS+ countries in the context of crisis instabilities in 2019−2024. Financial markets are becoming more integrated, and an increasing share of public investments are carried out across borders, which increases not only the opportunities for participants, but also the risks of a new crisis. The work used data on central bank rates of the considered countries, yield indices of 10-year government bonds, gold and Brent oil prices. The methods include the analysis of exchange rate dynamics, connectivity estimates based on the multivariate concordance coefficient and two-factor Friedman rank variance analysis, VAR models, Granger predictability and cointegration. The objective of this study is to analyze the interrelationship and cointegration between the sovereign bond and equity markets of selected BRICS+ countries during crisis periods. Our findings indicate that market interrelationship intensifies during crises, which in turn amplifies volatility. Additionally, we observed that none of the economies within the BRICS+ group can be classified as fully integrated or entirely isolated markets. The disruption of the interrelationship in the sovereign bond markets of the group is primarily reflected in the inconsistency of dynamic changes between Russia, China, and India. During the global shock of 2019–2020, the crisis spread from China, followed by Indonesia, and later to the other countries of the group. The financial and debt markets of the sampled countries were able to quickly cope with the severe shocks of the COVID-2019 period. The 2022–2024 crisis, which lasted significantly longer, began in Russia before spreading to countries across Asia and Africa. By 2024, Russia’s sovereign bond yields showed a marked decline. The increased market volatility following 2022 disrupted the integration and interrelationship of the stock and debt markets within the BRICS+ countries.
Mitigating anticipated medicine shortages through inter-facility medicine sharing
Authors: Tippong Danuphon , Jomthanachai Suriyan , Dankittikul Thamonwan
Published: November 2024

This study develops an optimisation model to facilitate inter-facility medicine sharing in response to anticipated medicine shortages. These facilities include hospitals and medical representatives. We adopt the concept of collective response proposed in our study literature. The optimisation model is developed according to the real-world practices of inter-facility medicine sharing. We utilise case studies of particular healthcare networks to demonstrate the efficacy of the developed model. The efficacy encompasses the model’s application to real-world case studies, as well as its validity and reliability within a specific system. The results show that the developed model is able to determine which facilities should share the requested amount of medicines; and to reduce total lead times by at least one day compared to the ones obtained in the current practice. The model can be used as a decision-support tool for healthcare practitioners when responding to shortages. The study presents the managerial implications of medicine sharing at the network level and supports the development of collaboration amongst facilities in response to medicine shortages.
Enhancing intersection safety: Testing measures to reduce law violations in Loja (Ecuador)
Authors: García-Ramírez Yasmany , Carvallo Sebastián
Published: November 2024

This study evaluates the effectiveness of measures aimed at reducing traffic violations, specifically focusing on wrong-way driving, at intersections in Loja, Ecuador. The high incidence of accidents at these intersections, often resulting from wrong-way driving and non-compliance with traffic regulations, underscores the critical need for effective strategies to enhance road safety. To address this issue, we adopted a multidisciplinary approach to assess the impact of two specific interventions: the implementation of official warnings and the presence of traffic officers at a selected intersection. Data collection involved recording instances of traffic violations, administering road safety surveys, and monitoring the implementation of these interventions. The post-implementation analysis sought to determine the effect of these measures on driver behavior and overall traffic safety. Our findings indicate that while the interventions succeeded in increasing awareness about traffic violations, they did not produce a significant reduction in undesirable driving behaviors. This suggests that, although the presence of warnings and traffic officers is beneficial in raising awareness, these measures alone may not be sufficient to effect substantial behavioral changes. The research provides valuable insights for the development of more comprehensive road safety strategies and emphasizes the need for further studies to explore and address the underlying causes of traffic violations.
An insight of undergraduate students’ attitude and satisfaction with online home-based learning system
Authors: Wong Ling Chai , Song Bee Lian , Ooi Bee Wah , Lim Ming Fook , Tee Poh Kiong
Published: November 2024

The purpose of this study is to investigate different factors associated with remote online home-based learning (thereafter named OHL), including technical system quality, perceived quality of contents, perceived ease of use, and perceived usefulness in relation to the satisfaction of undergraduate students following the post-COVID-19 pandemic in Malaysia. Additionally, the mediating roles of attitude are also investigated. Two hundred questionnaires were distributed using judgmental sampling method and 156 completed responses were collected. The data were subsequently analyzed using PLS-SEM. The findings imply that the OHL system is an effective method although it is challenging to operate. In terms of perceived technical system quality, OHL is currently more gratifying for students; however, some have reported that the quality of the content delivered via the remote system is still unsatisfactory. Moreover, the study found that attitude is a significant determinant of undergraduates’ satisfaction with OHL. This study contributes to the advancement of current knowledge by inspecting the factors of the Undergraduate Level OHL System using the mediating roles of attitude. In terms of underpinning theories, Technology Acceptance Model and Information System Model were employed as the guiding principles of the current study.
Long-Term Changes in Composition and Distribution of Bumblebees in Urban Areas
Authors: Michołap Paweł , Sikora Aneta , Sikora Marcin , Zając Krzysztof , Kadej Marcin
Published: November 2024

The distribution of bumblebee species in Wrocław (SW Poland) was studied based on data from ten UTM grid squares between 1879 and 2018, and the composition and abundance of bumblebee species between 2011 and 2018. The results were compared with historical data available for the last 139 years, including published materials and collections of the Museum of Natural History (University of Wrocław). Twenty-six bumblebee species, including six species of cuckoo bumblebees of the subgenus Psithyrus, were recorded. One species was not confirmed during the later period, nine were strongly decreasing both in the range of distribution, seven other were expanding significantly in Wrocław and three were new in the Wrocław city boundaries. Negative and positive tendencies resulted from both anthropogenic and natural factors. All bumblebees that appeared in the city of Wrocław and increased their abundance were species that prefered forest and shrub areas, while species that disappeared from the city and decreased in numbers were species who prefered open areas.
Student- Centered Learning, Teaching and Assessment – Student Opinion
Authors: Todorova Irina
Published: November 2024

Objective: The purpose of this study is to determine Technical' subjective perceptions of the extent to which learning, teaching and assessment at the university are student-centered.  
 
Theoretical Framework: The study draws on Part 1.3 of the Standards and Guidelines for Quality Assurance in the European Higher Education Area (ESG) - Student-centered learning, teaching and assessment and the results of an empirical study regarding students' subjective perceptions of the implementation of this standard.
 
Method: The methodology adopted for this study comprises a review of research related to the indicators that students use when assessing the degree to which learning is oriented to them and A Tool for Measuring Students' Opinions about the Degree in Which Learning and Teaching are Oriented to Student, created in 2021 at the Department of Social and Legal Sciences of the Technical University of Varna to assess the implementation of Part 1.3 of the Quality Standards for Higher Education.
 
Research Implications: The research conducted shows that the newly developed tool can help in understanding the extent to which learning, teaching and assessment have been student centered. The application of the questionnaire can provide valuable insights into students' subjective perceptions as well as the areas where the implementation of ESG guidelines needs to be improved.
 
Originality/Value: We believe that the main contribution of this study is in providing evidence for the use of a questionnaire directly aimed at assessing and self-assessing the extent to which ESG standards and guidelines relating to learning and teaching are being met.
Potential of silk proteins in cosmetics
Authors: Qadir Jasmeena , Islam Tajamul
Published: November 2024

Synthetic and inorganic chemical ingredients in cosmetic products pose serious health impacts on skin and hair. Much emphasis has been laid on the development of cost-effective, eco-friendly and user-friendly cosmetic products from time to time. Manufacturing cosmetics using natural ingredients is considered as a viable alternative to overcome the side effects of synthetics. Silk is a natural biopolymer obtained from cocoons of sericigenous insects like silkworms. It constitutes two proteins, viz., fibroin and sericin. Fibroin is the central core protein glued with sericin protein forming silken cocoons together. Both the proteins possess remarkable attributes viz, anti-microbial, anti-oxidant, anti-tyrosinase activity, efficient UV resistance, kinase activity, excellent release and absorption of moisture. The silk protein attributes are advantageous for body skin, hair and nails. It possesses a wide range of cosmetic applications such as facilitation of hair growth, improvement in softening and lustre of hair, rejuvenation of body and skin cells, UVB protection, prevention of chapping and brittleness of nails, and skin brightening. Due to its low molecular weight, easily penetrates the hair strands and skin cells, binds the keratin in hair and forms a protective layer to prevent moisture loss. A wide range of products have been developed for use in cosmetics viz., SILKPRO, SILKALL, SILKPRO 1000. These products are used as natural ingredients due to their potent applications in cosmetics. The cosmetic industry can be developed by proper utilization of silk in its organic products while promoting value addition to sericulture industry.
Регіональні особливості інфраструктурного розвитку сільських територій в період повоєнного відновлення
Authors:   Харківський національний економічний університет імені Семена Кузнеця, Перепелюкова Олена , Попело Ольга ,   Національний університет «Чернігівська політехніка»
Published: November 2024

У статті досліджено проблеми інфраструктурного розвитку сільських територій у період повоєнного відновлення. Обґрунтовано, що регіональні особливості інфраструктурного розвитку сільських територій залежать від низки факторів, які відрізняються залежно від географічного положення, соціально-економічних умов, природних ресурсів і культурних традицій. Досліджено стан регіонального розвитку за показником виробництва продукції сільського господарства, що дало змогу виокремити регіони лідери та регіони, які мають іншу спеціалізацію. Проаналізовано обсяги завданої шкоди в сільському господарстві за категоріями, визначено необхідні ресурси для відновлення територій в повоєнний період. Окреслено пріоритети відновлення та реконструкції сфери сільського господарства.
Розвиток платіжної інфраструктури в умовах сучасних викликів
Authors:   Національний університет «Чернігівська політехніка», Тарасенко Артем , Підзамецький Андрій ,   Національний університет «Чернігівська політехніка», Суховецький Володимир ,   Національний університет «Чернігівська політехніка»
Published: November 2024

У статті обґрунтовано роль платіжної інфраструктури в забезпеченні стабільності та ефективності розвитку фінансової системи країни. Досліджено вплив впровадження міжнародного стандарту ISO 20022 на діяльність платіжної інфраструктури України. Наведено складові платіжної інфраструктури та надано їхню характеристику. Здійснено систематизацію видів платіжних послуг за різними класифікаційними ознаками. Проаналізовано розвиток платіжної інфраструктури України протягом 2018-2023 рр., виокремлено основні виклики та запропоновано ключові напрямки, які потребують уваги для стабільного та ефективного її функціонування в майбутньому.
Інноваційно орієнтований розвиток бізнес-процесів на малих підприємствах
Authors:   Національний університет «Чернігівська політехніка», Коваль Крістіна , Стеченко Олександр ,   Національний університет «Чернігівська політехніка»
Published: November 2024

У статті розглянуто основні теоретичні аспекти управління інноваційним розвитком бізнес-процесів малих підприємств. Метою статті є удосконалення існуючих теоретичних підходів формування ефективної політики підприємства малого бізнесу в напрямку впровадження інноваційних бізнес-процесів. Обґрунтовано важливість розвитку бізнес-процесів за сучасних умов функціонування малих підприємств. Розглянуто прикладні аспекти державної підтримки інновацій у бізнес-процеси у провідних країнах світу. Визначено основні властивості бізнес-процесів малого підприємства. Розглянуто концептуальні аспекти стратегічного управління інноваційним розвитком бізнес-процесів у контексті взаємного впливу параметрів бізнес-процесу та стану зовнішнього середовища. Запропоновано впровадження системи моніторингу інноваційним розвитком бізнес-процесів.
Blacksmith: Between history, culture, and economy
Authors: Suryana Aan , Pajriah Sri , Fajriyah Izzatul
Published: November 2024

This research was aimed at describing the historical, cultural, and economic value of blacksmith activities. The research method used was a literature study (library research). Data collection techniques were carried out through collecting research results that had been carried out and published in reputable indexed journals, Google Scholar, etc. The research results showed that blacksmithing had historical value whose development varied in each region of the world. In Asia, especially Indonesia, the historical development of blacksmithing was estimated to have existed since the 7th century AD. This was based on findings on temple wall reliefs, inscriptions, and ancient manuscripts found as relics from the royal era. Meanwhile, the historical development of blacksmiths in Europe, Africa, and other Asian regions was quite diverse, having developed from 1150-1400 BC. The blacksmiths of Dokdak Village also had cultural values ​​that were very important to be passed on. This was based on data which showed that in blacksmithing activities there were cultural elements, namely the knowledge system, livelihood system, and equipment and technology systems used. Furthermore, Dokdak Village's blacksmith activities had economic value, because the carried-out activities could produce production goods that have economic value. Based on this, it is important to protect and maintain the livelihood of blacksmiths to pass on values ​​to the younger generation.
Traditional massage “Peuseul” for pregnant women in Kuta Village and its impact on pregnant women's well-being: A qualitative study
Authors: Ningrum Widya Maya , Purnamasari Kurniati Devi , Fatimah Siti
Published: November 2024

“Peusuel” is a traditional massage practice performed on pregnant women in Tatar Sunda, believed to have various benefits for maternal and fetal health. This study aims to explore how Peusuel is implemented, understand the experiences of pregnant women who undergo Peusuel, and evaluate its impact on their physical and emotional well-being. The observed variables include physical discomfort levels (such as back pain, swelling, and fatigue), emotional states (including anxiety and mood changes), and social connectedness. The key parameters measured were frequency and duration of the Peusuel sessions and the involvement of community members in the process. Using qualitative research methods, particularly in-depth interviews and participant observations, data were collected from pregnant women who have experienced Peusuel, as well as from traditional practitioners and family members involved. Data were analyzed through thematic analysis to identify recurring patterns and insights. This analysis revealed that Peusuel not only helps reduce physical discomfort during pregnancy but also contributes to emotional relief by alleviating anxiety and stress. Additionally, it strengthens social and cultural ties between pregnant women and their communities, creating a sense of belonging and support. This study provides important insights into the preservation and development of the traditional practice of Peusuel in the context of modern health, while also highlighting its potential integration as a complementary approach in maternal care.
ОСОБЕННОСТИ АНТИБАКТЕРИАЛЬНЫХ СВОЙСТВ ТИТАНОВЫХ ИМПЛАНТАТОВ С НАНОСТРУКТУРИРОВАННЫМИ ПОКРЫТИЯМИ
Authors: М.Б. Тлешев , Б.Ж. Нысанова , Р.И. Кульманбетов , К.Д. Алтынбеков
Published: November 2024

Введение: Исследование посвящается изучению свойств модифицированных покрытий титановых имплантатов. Титановые пластины используются в медицине благодаря их биосовместимости и прочности. Однако они подвержены коррозии и бактериальной колонизации, что может вызывать инфекции и сокращать срок службы имплантатов. Для улучшения этих свойств применяются наноструктурированные покрытия. Допирование таких покрытий серебряными наночастицами (Ag) может повысить их бактерицидные свойства. Ожидается, что такие покрытия улучшат функциональные характеристики имплантатов, делая их более безопасными и долговечными. Цель исследования: изучить антибактериальные свойства титановых имплантатов с наноструктурироваными поверхностями и допированные частицами серебра. Материалы и методы исследования: антибактериальные свойства покрытий оценивались методом дискодиффузии на питательном агаре Мюллера-Хинтона на штаммах S. sobrinus, S. mutans и S. aureus Результаты и обсуждение: Результаты показали, что все исследуемые образцы не показали зон задержки роста бактерий для штаммов S. sobrinus, S. mutans и S. aureus. Это указывает на резистентность бактерий к данным покрытиям, и необходимость дальнейших исследований для улучшения антибактериальных свойств имплантатов. Заключение: Представленные покрытия не обеспечивают достаточной антибактериальной активности против тестируемых штаммов бактерий. Для улучшения антибактериальных свойств необходимо проводить дальнейшие исследования по оптимизации концентрации и распределения серебра в покрытии.
Dearomative Selective Reduction of Structurally Diverse N-Heteroarenes Enabled by Titanium Catalysis
Authors: Natte Kishore , Bhatt Tarun , Vadithya Suman , Choudhary Mridula , Singh Saurabh Kumar
Published: November 2024

The reduction of aromatic compounds is a stalwart transformation in modern organic synthesis since it allows the generation of novel complex three-dimensional (3D) chemical entities from two-dimensional precursors (2D), linking readily available aro-matic feedstocks with unobtainable alicyclic structures. However, controlling the high level of selectivity of N-heteroarenes (quinolines and pyridines), particularly substituents positioned on the reducible quinoline ring, is both intriguing and challeng-ing, and methods for selective saturation of structurally complex derivatives (multiple aromatic rings) are rarely unaddressed and need some advances. Also, many approaches suffer from scalability problems as well as high cost and low availability of both catalysts and tailor-made ligands. To address this issue, we herein report the first example of commercially available ti-tanocene dichloride (Cp2TiCl2)-catalyzed dearomative selective reduction of structurally diverse nitrogen-based heteroarenes with ammonia borane as a reducing agent (>100 examples). The developed protocol features the advantage of chemoselectivity and wide functional group tolerance of quinolines. Meanwhile, the efficient reduction of challenging and unprotected functional-ized pyridines as well as pyrazines is also furnished with remarkable functional group preservation and also with an improved F(sp3) carbon fraction. Additionally, a few selected furans and benzofuran derivatives were also successfully demonstrated un-der synthetically relevant conditions, and gram-scale synthesis was effectively executed. The methodology can be extended to the saturation of complex N-heteroarenes with conserved selectivity. In addition, density functional theory (DFT) calculations were carried out to shed light on the mechanistic insights into the reduction of quinoline.
Reversible Small Molecule pan-Ras Inhibitors Display Tunable Affinity for the Active and Inactive forms of Ras.
Authors: Parry Charles , Pellicano Francesca , Schüttelkopf Alexander W. , Beyer Kim , Bower Justin , Bryson Amy , Cameron Kenneth S. , Cerutti Nichole M. , Clark Jonathan P. , Davidson Stuart , Davies Keneth , Drysdale Martin J. , Engelman Jeffrey , Estevan-Barber Anna , Gohlke Andrea , Guthy Daniel A. , Hong Min , Hopkins Alana , Hutchinson Luke , Konczal Jennifer , Maira Michel , McArthur Duncan , McKinnon Heather , Nepravishta Ridvan , Ostermann Nils , Pasquali Camila , Pollock Katie , Pugliese Angelo , Rooney Nicholas , Schmiedeberg Niko , Shaw Paul , Velez-Vega Camilo , West Christopher , West Ryan , Zecri Frederic , Taylor John B.
Published: November 2024

Activating mutations of Ras are one of the most prevalent drivers of cancer and are often associated with poor clinical outcomes. Despite FDA approval for two irreversible inhibitors that target the inactive state of KRasG12C, significant unmet clinical need still exists, and the susceptibility of non-G12C mutants to inactive-state inhibition remains unclear. Here we report the discovery of a novel series of reversible inhibitors that bind in an enlarged version of the switch I-II pocket with nanomolar affinities. Dependent on chemotype these can either preferentially bind to the inactive or active state or bind both with similar affinity. The active-state binders inhibit the Raf interaction for wild-type Ras, and a broad range of oncogenic KRas mutants with nanomolar potency. A sub-series of these molecules displays cellular inhibition of Ras-Raf binding, as well as decreased phosphorylation of the downstream protein ERK, demonstrating that potent pan-Ras inhibitors can be accessed from this novel pocket.