bluuebunny/crossref_metadata_2025 huggingface dataset:
Creation of a Strategically Oriented Social Responsibility Management System in a Georgian Organization
Authors: Chechelashvili Maia , Chikviladze Nino , Iashvili Irina , Kajaia Tamar , Kharkhelauri Khatuna , Malania Elisabed
Published: September 2024

For Georgia, a country actively seeking integration with European and global markets, creating a strategically oriented system of social responsibility management in Georgian organizations can become a key factor of competitiveness. The research aims to identify the key components of a strategically oriented social responsibility management system and to study the problems accompanying its integration into the strategy of Georgian organizations. In the research process, methods of analysis and synthesis, statistical methods, time series visualization, induction and deduction, and systematic approach were used. Data were collected through surveys using Computer Assisted Web Interviewing (CAWI) and processed in Microsoft Excel. The study confirms the importance of a strategic approach to corporate social responsibility in Georgian organizations for sustainable development and integration into international markets. Using decomposition, key problems of effective implementation of corporate social responsibility are identified, among which regulatory uncertainty and strategic integration are highlighted as the most relevant for Georgian organizations; components of an effective social responsibility management system are formed. The actions, the implementation of which constitutes an adaptive algorithm for the formation of a strategically oriented system of social responsibility management, capable of ensuring the organization’s competitiveness in the long term, are defined. In the example of existing organizations, the significance of problems related to the implementation of socially responsible behavior and the assessment of the formation of key components of a strategically oriented system of social responsibility management are evaluated. It is recommended to switch from a tactical approach to social responsibility management to a strategic one, integrating it into corporate strategy and focusing on solving real social and environmental problems. The results of the study can be used by organizations as a roadmap for incorporating social responsibility into their strategy, which will contribute to increased competitiveness and long-term sustainable growth.
Enhancing Student Mathematical Proficiency through Planimetry and Digital Technologies
Authors: Hetmanenko Liudmyla
Published: September 2024

Active societal development drives the dynamics of educational approaches to acquiring fundamental knowledge and skills by learners. The necessity of integrating innovative pedagogical technologies into mathematical curricula is prompted by changes in the general processes of perception and thinking among students, as well as the need to adapt educational strategies to these dynamics. The research assesses the impact of planimetric methods and technologies on geometry learning. The research methods used were analysis of literature, pedagogical experiments, and questionnaires of students and teachers. The outcome revealed that incorporating digital technologies and interactive activities enhances the learning of geometrical concepts and boosts students' interest. The results also indicated that the group of students who underwent instructions in line with the study's research hypotheses provided higher solutions to geometric problems than the control group. Questionnaires supported the positive attitude of students and teachers towards the new approaches, noting the enhanced comprehension of the matter and the enhanced interest in the materials. The practical value of the results is in elaborating the methodological recommendations for using digital technologies and planimetric methods in the educational process, which may help enhance the quality of mathematics instruction. Some of the drawbacks of the current study include the generalisability of the results, which suggests the importance of further optimising the ratio of traditional and new teachings applied in the study. The further development direction of the examined field of study is the fine-tuning of the approaches to using technology-enhanced learning activities to boost the efficiency of the teaching-learning process.
Evaluation of the Effectiveness of Using STEAM Projects in Teaching Physics: Student Interest in the Field of Solar Energy
Authors: Pattayev Amin , Genc Naci , Ramankulov Sherzod , Polatuly Serik , Tuiyebayev Meirbek , Usembayeva Indira , Rizakhojayeva Gulnara
Published: September 2024

Scientific works of recent years show that students' interest in physics is comparatively declining. Given the importance of physics in the development of science and technology, it is obvious that the reduction in the number of specialists in this field causes concern in the economy of any country. Therefore, at present, the organization of advanced STEAM experiments and the effective use of STEAM educational software are taking an increasingly important place in the education system of developed countries. The purpose of this study is to assess the impact of using the STEAM project method, integrative scientific and technological, engineering, art and mathematical education (STEAM) on the development of interest among students in the physics specialty. The study was attended by 212 second-year students from the Kazakh-Turkish University named after Khoja Ahmed Yasawi and the South Kazakhstan University named after M. Auezov. Research work was carried out in both groups during the training of the course "Alternative energy sources". In the control group, this course was taught in the traditional way, and in the experimental group, classes based on STEAM projects were conducted. The educational process continued for 15 weeks. In this feature, pre- and post-participation calculations, especially surveys, and progress calculations are used to create a student score. The results of the study indicated that STEAM products developed by the authors together with students and used in the educational process are effective. Progressive results increase in the observation of the physics parse was high and the progressives were included. Student relationships in physics increased by 35% in the experimental group, compared to 10% previously. Through the implementation of STEAM projects, it was noticed that students' interest in physics increased to a significant extent. The article presents STEAM educational resources and materials developed by the authors and recommendations for their use in the educational process.
Risco de queda em idosos internados em um Hospital Universitário
Authors: Ramos Joyce Rocha , Souto Bruna Silva , Moura Luiza Taciana Rodrigues de
Published: September 2024

Objetivo: analisar o risco de quedas em idosos hospitalizados. Métodos: Estudo transversal, descritivo e observacional realizado em um hospital universitário. A população do estudo foi composta por pessoas de ambos os sexos, internadas nas unidades de internação cirúrgica e clínica médica, com idade igual ou superior a 60 anos. A coleta de dados ocorreu por meio de instrumento estruturado para obtenção de informações sociodemográficas e clínicas, risco de quedas com Escala Morse e ações implementadas para redução de riscos. A análise dos dados foi realizada por meio de estatística descritiva simples e análise da associação entre variáveis sociodemográficas e clínicas e risco de quedas segundo a escala de Morse, utilizando-se os testes Qui-quadrado e Fisher, com nível de significância de 5% e p-valor ≤ 0,05. Resultados: Dos 174 participantes, a maioria era do sexo masculino (51,72%), com diagnóstico de doenças cardiovasculares (39,65%), tempo de internação de 0 a 4 dias (51,72%). Observou-se que 57% dos idosos apresentaram alto risco de queda, 14,94% possuíam calçados seguros, 97,12% dos leitos não possuíam companhia funcional e 17,81% dos pacientes possuíam pulseira de identificação de risco. Conclusão:  A maioria dos idosos apresentou alto risco de quedas, além disso, há falhas na implementação de medidas de prevenção pela instituição hospitalar que favorecem o risco de quedas e, consequentemente, implicam na qualidade da assistência.
267 Milliarden Euro Schaden
Authors: Sachs Melanie
Published: September 2024

Deutsche Unternehmen rücken verstärkt in den Fokus von Angreifern aus dem In- und Ausland. Zwei Drittel fühlen sich durch Cyberangriffe sogar in ihrer Existenz bedroht.
„Ein echter Gamechanger“
Authors: Sachs Melanie
Published: September 2024

Eine neue Thermoform-Anlage für Weichfolien-Verpackungen produziert bei dem Unternehmen Süddeutsche Truthahn für ausgewählte Produkte. Im Vergleich zur vorherigen Lösung bringt sie den 3,5-fachen Einsatz. Ihre Pluspunkte: sparsamer Materialeinsatz, Hygienic Design sowie ein praktisches Werkzeugwechselsystem.
Bedarfsgerechte Transportsicherung
Authors: Sachs Melanie
Published: September 2024

Ausgestattet mit Maschinen von Mosca umreift und umwickelt die Firma Zerhusen automatisiert ihre Wellpapp-Waren – und kann sich durch konstante Prozesse ganz auf die Produktion konzentrieren.
Lactalis verstärkt sich mit Zukäufen in USA und Südafrika
Authors: Krönert Alrun
Published: September 2024

Die französische Lactalis-Gruppe verleibt sich mit Yoplait eine der bekanntesten Joghurtmarken auf dem US-Markt ein. Der Konzern, der mittlerweile die 30 Mrd. USD-Umsatzmarke geknackt hat, setzt seine globale Akquisitionstour auch in Südafrika fort.
Edeka Hessenring automatisiert
Authors: Bökamp Lena
Published: September 2024

Edeka Hessenring plant den Bau eines neuen Zentrallagers und setzt dabei erstmals auf Automatisierung. Die Ausschreibungsphase steht nach LZ-Informationen kurz vor dem Abschluss. Projektleiter Martin Steinmetz erhält eine neue Rolle.
Media-Markt-Saturn zieht Omnichannel-Warenwirtschaft um
Authors: Klug Denise
Published: September 2024

Der Elektronikhändler Media-Markt-Saturn hat den Umzug des Omnichannel-ERP-Systems auf SAP S/4 Retail bewältigt. Trotz der Größe des Projekts folgte er agilen Methoden.
Konzertierte Aktion fürs Verpackungsrecycling
Authors: Subklew Axel
Published: September 2024

Effektive Kreislaufwirtschaft für Verpackungen hängt davon ab, wie sorgfältig und kompetent Abfall im Haushalt sortiert wird. Die dualen Systeme haben die Bevölkerung im Sommer deutschlandweit erstmals auch im direkten persönlichen Dialog informiert – gemeinsam mit Kommunen, Entsorgern und drei LEH-Filialisten, inklusive Edeka.
Tannenhof erzielt leichtes Absatzplus
Authors: Heimig Dieter
Published: September 2024

Der Rohwurstbereich ist das wichtigste Standbein von Tannenhof. Das Unternehmen will aber auch mit neuen Kochschinken-Spezialitäten punkten.
Regionalität hat Vorrang
Authors: Heimig Dieter
Published: September 2024

Die Verantwortlichen der Hieber’s Frische Center KG legen Wert auf mehr Tierwohl und haben dabei auch die Transporte zur Schlachtung im Blick.
Economia destruidora e antropoceno: Relato dos trabalhos de campo realizados em 2023 no alto curso, na foz e planície costeira do rio Doce, Brasil
Authors: Vieira Luiz Henrique , Silva Ana Paula Félix de Carvalho , Zanotelli Claudio Luiz
Published: September 2024

O presente artigo aborda os desdobramentos do rompimento da barragem de rejeitos de minério de ferro de Fundão, pertencente à empresa Samarco e localizada no município de Mariana (MG), ao longo da bacia do Rio Doce nos estados de Minas Gerais e Espírito Santo, Brasil. Através de registros de dois trabalhos de campo realizados em 2023, discorremos sobre os efeitos da mineração como atividade inserida na dinâmica de uma economia que se reproduz de forma destruidora. Para tanto, mediante ao diálogo com as pessoas atingidas e às percepções da paisagem, adentramos nos territórios contaminados e constatamos as graves consequências sobre o meio anos depois do rompimento, problematizando, assim, o discurso do desenvolvimento econômico amplamente reproduzido na sociedade frente aos graves problemas socioambientais em que vivem as populações das localidades ao longo da bacia do Rio Doce.
Sumário
Authors: De Sousa Gustavo Mota
Published: September 2024

Sumário
¿Despertará por fin el pueblo hondureño?
Authors: I. M.
Published: September 2024

No abstract available.

ECA Estudios Centroamericanos, Vol. 41, No. 450, 1986: 331-334.
Phytochemical and Acute Toxicity Assessment of Syzygiumguineense (Willd.) DC. and Acaciahockii De Wild. Traditionally used for Female Contraception/fertility regulation in BaringoCounty, Kenya
Authors:   Department of Chemistry and Biochemistry, School of Science, University of Eldoret, P.O Box 1125-30100, Eldoret, Kenya, Kiptisia Richard T. , Nandwa Anastasia ,   Department of Biological Sciences, School of Science, University of Eldoret, P.O Box 1125-30100, Eldoret, Kenya
Published: September 2024

A boiled stem bark mixture of Syzygiumguineense and Acacia hockii is traditionally used by the Tugen community in Baringo County, Kenya, for fertility regulation in women. This study aimed to validate the safety and efficacy of these plants through phytochemical screening and acute oral toxicity tests. Standard phytochemical tests were employed to identify the compounds present in the stem bark extracts. Acute toxicity was evaluated following the Acute Toxicity Class model based on the OECD 423 Guideline (2001). The study was conducted between April and July 2024 at the Department of Chemistry & Biochemistry for sample extraction and phytochemical analysis, and the Department of Biological Sciences, University of Eldoret, for toxicity testing.The stem bark extracts of both plants contained tannins, saponins, flavonoids, glycosides, alkaloids, terpenoids, steroids, and phenols, according to phytochemical screening conducted using established procedures. Rats were used in acute oral toxicity experiments, with each plant extract administered at a set dose of 2000 mg/kg body weight. The rats were split into test and control groups. Over the course of 14 days, signs of toxicity and death were noted every day, and body weights after fasting were recorded once a week. The fact that no deaths or changes in physiological indicators were noted during the trial suggests that the LD50 is higher than 2000 mg/kg. Furthermore, the rats fed with the extracts showed a consistent increase in their fasting body weights when compared to the control group (p = 0.05). This study concludes that the ethnobotanical use of Syzygiumguineense and Acacia hockii is safe based on acute toxicity results. The phytochemical compounds present may be responsible for the plants’ pharmacological effects in traditional medicine. However, further long-term toxicity studies are recommended to fully assess the toxicological profile and reinforce the clinical significance of these findings.
Legal, Regulatory, and Economic Dimensions of Poverty Alleviation Strategies in Brunei Darussalam: An Examination towards Achieving the Global SDGs
Authors: AHMAD Nehaluddin , Zamri Zheimie H. , Hakim Iskandar Abdul
Published: September 2024

Efforts to combat poverty have posed a persistent challenge globally, impacting societies and governance throughout history. In Brunei, poverty reduction strategies are aligned with the country’s Vision 2035 and the Sustainable Development Goals (SDGs). This study aims to examine the legal, regulatory, and economic dimensions of poverty alleviation, as well as investigate the challenges faced by Brunei in implementing these strategies and offer recommendations. Using a qualitative research framework, this study employs document analysis and observational methods to delve into the implementation of poverty reduction strategies. Drawing from various sources such as academic literature, reports, and official documents, we assess the suitability of these strategies for Brunei’s Vision 2035 and the SDGs. The key findings highlight both the strengths and limitations of current approaches, providing valuable insights for policymakers and stakeholders. Ultimately, this research seeks to raise awareness and understanding of poverty dynamics in Brunei, contributing to the ongoing discourse on effective socio-economic development strategies.
Perspectives For the Development of Transport In Romania by 2050
Authors: FISTUNG Frantz Daniel , NEAGU Cornelia , BULEARCA Marius , SIMA Cristian
Published: September 2024

This study aims to present the new trends in the development of transport in Romania, and mainly of the specific infrastructure network, in the context of the growing demands for sustainable development of the society and the inadequate situation of transport caused by past and current errors induced by the Romanian authorities in this area. As a member of the common transport market within the EU, Romania needs to experience a paradigmatic change in the transport sector’s development strategy by taking all the necessary measures to achieve the sustainable mobility target. Unfortunately, this goal is difficult to achieve both due to the inertia of policies developed in the past in this economic sector, but unfortunately also due to the instability generated by the inconstancy of the vision and the maintenance of the development objectives of the transport system in Romania. The inadequate situation of the national transport network was the main factor that led to diminishing the opportunities offered by Romania’s geo-political position. Energy consumption in the sector is increasing, causing huge environmental damage and especially in the production of greenhouse gases. Things can no longer continue in this way and therefore, the authors of the current study propose a series of measures aimed at leading to a profound change in the orientation of Romanian transport towards an accessible, efficient and protective sector in relation to the environment and the health of living creatures. The study is based on analyses of data related to urban localities on both national and international plans.
Foreign Emigration of Young Nurses from Socio-Economically Disadvantaged Regions. The Example of Nursing Students from The Main Academic Centres of Eastern Poland
Authors: KOWALEWSKA Grazyna
Published: September 2024

The aim of the research was to determine the tendency to emigrate nursing students from socio-economically weak regions. Additionally, the goals of trips abroad and the family’s influence on students’ migration plans were identified. The TOPSI method was used to identify voivodeships with the worst socio-economic situation, and the original research survey was the tool for verifying the set goals and hypotheses. The study covered five voivodeships of Eastern Poland (Warmińsko-Mazurskie, Podlaskie, Świętokrzyskie, Lubelskie and Podkarpackie). The study was conducted among nursing students at 5 major academic centers. 745 completed surveys were received.
INCLUSÃO TECNOLÓGICA E DIVERSIDADE NA FORMAÇÃO CONTINUADA DAS EQUIPES GESTORAS: UMA ANÁLISE DO USO DA PLATAFORMA MOODLE NO ACRE
Authors: Lima Adriana Alves de
Published: September 2024

A presente pesquisa tem como objeto de estudo a formação das equipes gestoras das escolas públicas do Acre, com foco na utilização da Plataforma Moodle para inclusão tecnológica e promoção da diversidade. O objetivo é analisar as potencialidades da plataforma para a formação continuada dessas equipes, explorando como seus recursos digitais (aulas, slides, vídeos, exercícios e fóruns) podem contribuir para uma formação mais acessível e inclusiva. A metodologia adotada combina abordagens qualitativas e quantitativas, avaliando tanto o impacto subjetivo da formação quanto o alcance em termos de quantidade de profissionais capacitados. A pesquisa de campo, realizada no primeiro semestre de 2019, incluiu visitas à Divisão de Formação e aplicação de questionários aos professores formadores responsáveis pelo material didático na plataforma. Os resultados indicam que a plataforma Moodle teve um impacto positivo no aumento do número de gestores formados, mas também revelou desafios significativos, como problemas com infraestrutura tecnológica e gestão de prazos, que afetaram o processo de formação. A conclusão sugere que, embora a plataforma ofereça uma alternativa valiosa para a formação continuada, é essencial enfrentar os obstáculos tecnológicos e logísticos para garantir uma inclusão efetiva e abrangente.
CARDIOMIOPATIA HIPERTRÓFICA: UMA REVISÃO DE LITERATURA
Authors: Ardisson Giulia Machado Caldeira , Souza Thifisson Ribeiro de
Published: September 2024

Esta revisão narrativa de literatura reuniu artigos publicados preferencialmente em inglês, espanhol, francês e português nos últimos cinco anos na base de dados PUBMED com o objetivo de revisar a cardiomiopatia hipertrófica, indicando suas manifestações clínicas, diagnóstico e tratamento. A cardiomiopatia hipertrófica (CMH) é uma doença genética cardíaca caracterizada pela hipertrofia do miocárdio, especialmente do septo interventricular, sem causa secundária aparente. A CMH pode levar à interrupção do fluxo de saída do ventrículo esquerdo, disfunção diastólica e aumento do risco de arritmias ventriculares e morte súbita, especialmente em jovens. O diagnóstico é feito por ecocardiograma, com o uso adicional de ressonância magnética cardíaca e testes genéticos para melhor avaliação. O tratamento inclui betabloqueadores e bloqueadores de canais de cálcio para manejo sintomático, além de procedimentos invasivos, como miectomia septal ou ablação com álcool, em casos refratários. Pacientes de alto risco podem se beneficiar do implante de desfibriladores. O manejo é individualizado e multidisciplinar, com foco na prevenção de complicações e na melhoria da qualidade de vida dos pacientes.
ABORDAGENS MINIMAMENTE INVASIVAS NO TRATAMENTO DE ANEURISMAS DA AORTA ABDOMINAL: UMA REVISÃO INTEGRATIVA
Authors: Dominguete Bruna Maria Guimarães , Toledo João Vitor de Sousa , Figueiredo Otho Melo de , Campos Thiago Marques Prado
Published: September 2024

As abordagens minimamente invasivas, especialmente a reparação endovascular de aneurismas (EVAR), têm revolucionado o tratamento dos aneurismas da aorta abdominal (AAA), proporcionando uma alternativa menos agressiva em comparação à cirurgia aberta. Esta revisão integrativa visa sintetizar as evidências atuais sobre a eficácia, segurança e limitações das técnicas minimamente invasivas no manejo de AAA. Foram analisados artigos científicos publicados entre 2013 e 2023, utilizando bases de dados como PubMed, Scopus e Cochrane Library. Os resultados demonstraram que a EVAR oferece benefícios significativos em termos de menor mortalidade perioperatória, tempo de internação reduzido e recuperação mais rápida. No entanto, desafios como a alta taxa de reintervenção devido a complicações, incluindo endoleaks e migração da endoprótese, ressaltam a necessidade de um acompanhamento prolongado. A escolha entre EVAR e cirurgia aberta deve considerar o perfil anatômico do paciente e os riscos a longo prazo, especialmente em pacientes com anatomias desfavoráveis. Conclui-se que, embora a EVAR seja uma abordagem eficaz, especialmente para pacientes de alto risco, a seleção criteriosa e o monitoramento a longo prazo são essenciais para garantir os melhores desfechos clínicos.
Contribución de los artistas plásticos baracoenses en la conformación de la identidad cultural municipio Baracoa
Authors: Londres Ramírez Yurannis , Navarro Lores Diosveldy , Brown James Anays
Published: September 2024

La concepción de la producción plástica como producción que refleja desde lo simbólico y lo comunicativo, la intención de conservar valores identitarios adquiere matices socioculturales no siempre considerados. La reflexión en torno a este tema sugiere preguntas que antes no se hacían. Entre dichas preguntas se ubica la siguiente ¿Cómo los artistas plásticos baracoenses han contribuido a la configuración de la identidad cultural en el municipio Baracoa? Se utilizó una metodología cualitativa, apoyándose en la revisión de fuentes bibliográficas y entrevistas a informantes claves, artistas plásticos baracoenses y directivos del sector de la cultura. Se determinó que el estudio de la producción plástica en Baracoa, ha permitido comprobar que lo identitario se refleja en la imagen citadina, vista a través de sus tradiciones, historias ancestrales, raíces comunes, estilos de vida cotidiana, motivaciones, creencias, valores, costumbres, y actitudes incluyendo la autenticidad del acto creativo y las posibilidades de originalidad artística, lo que permite distinguir algunos rasgos relevantes de la identidad cultural baracoense, todo lo cual ha permitido a los artistas plásticos baracoenses contribuir a la conformación de la identidad cultural en el municipio y su expresión artística complementa la visualidad citadina de símbolos que constituyen referentes para el reconocimiento individual y grupal, además de actuar como mediadora en la creación de un imaginario social producido a partir de la socialización y uso de los signos artísticos, como expresión de identidad.
El trabajo independiente multidimensional: retos a las universidades cubanas en el siglo XXI
Authors: Guach Estévez Jorge Luís , Hevia Carro Elizabeth
Published: September 2024

El presente artículo aborda el trabajo independiente en las universidadescomo un proceso complejo, dirigido a desarrollar los conocimientos, habilidades y valores para la actividad autónoma de los futuros profesionales en medio de las crecientesexigencias en las condiciones actuales. El objetivo es realizar un acercamiento al problema desde las prácticas de la carrera de Gestión sociocultural para el desarrollo de la Universidad de Holguín, los avances logrados y las insuficiencias que se manifiestan, así como las vías para su perfeccionamiento.Para la consecución del objetivo se realizó un análisis cualitativo de clases, guías de trabajo independiente, participación en talleres, seminarios y clases prácticas, así como intercambio metodológico con profesores y alumnos.Se determinó como variables fundamentales a evaluar la calidad en la planificación de trabajo independiente en relación a los objetivos de los años académicos y los problemas profesionales, así como la multidimensionalidad en el tratamiento y exigencias de las actividades tendientes al desarrollo de la autonomía creadora. Los resultados alcanzados en la investigación permiten servir de punto de partida para la mejora continua. Se concluyeque, en las condiciones actuales, se impone un cambio progresivo de paradigma en las prácticas pedagógicas, donde los sujetos fundamentales del proceso son los alumnos, necesitadoscada vez más, de un empoderamiento integral que les permita de forma independiente y creativa resolver los complejos problemas a los cuales se deberán enfrentar como profesionales competentes.
Relevancia de la inserción sociolaboral en el proceso de activación de mujeres supervivientes de violencia de género
Authors: Rodríguez Valladolid Natalia , Galán Rello Daniel
Published: September 2024

En el presente artículo se aborda la problemática de la violencia de género y su impacto en la inserción sociolaboral de las mujeres violentadas, resaltando la importancia del acceso al empleo y la autonomía económica para su recuperación y alejamiento de sus agresores. Se presentan teorías explicativas de la violencia de género y se destaca su impacto negativo en la salud y la empleabilidad de las mujeres, así como el concepto de interseccionalidad en su vulnerabilidad laboral. Se resalta la importancia de la inserción sociolaboral como parte integral del proceso de recuperación y empoderamiento de las mujeres afectadas por la violencia de género.
PREVENTION OF VENOUS THROMBOSIS IN SURGICAL PRACTICE
Authors:   Belarusian State Medical University, I. Romanova , I. Kozhanova ,   Belarusian State Medical University, O. Kardash ,   Belarusian State Medical University, S. Mackevich ,   Belarusian State Medical University, V. Sirenko , V. Hryshchanovich ,   Belarusian State Medical University, N. Klimchuk , I. Kozich , A. Pichugina , I. Smirnova , T. Chak , А. Koroleva
Published: September 2024

Currently, arterial and venous thrombosis are among the leading causes of morbidity and mortality. Anticoagulant therapy is one of the most popular approaches in practical medicine in the treatment and prevention of thrombotic conditions. The article presents the most commonly used direct-acting anticoagulants in clinical practice and their comparative clinical and pharmacological characteristics. The main provisions of recommendations for medical prevention of venous thrombosis are given, taking into account the nature of surgical procedures and patient risk factors. The features of the use of low molecular weight heparins and unfractionated heparin against the background of regional anesthesia are given. Algorithms for interrupting antithrombotic therapy during planned and emergency surgical interventions are presented.
VARIANT ANATOMY OF THE SEMILUNAR LEAFLETS OF THE AORTIC AND PULMONARY VALVES BASED ON LITERARY DATA
Authors:   Belarusian State Medical University, H. A. Pasiuk , N. A. Trushel ,   Belarusian State Medical University
Published: September 2024

The article presents contemporary domestic and foreign literary data on the variant anatomy of the aortic and pulmonary semilunar leaflets. The anatomical features are shown include the differences in the structure and number of semilunar leaflets, of their structural asymmetry, and the variation in morphometric characteristics. Attention is given to the changes in anatomical terminology since 2019, which now distinguishes the valvular complex of the heart, consisting of the fibrous skeleton of the heart, atrioventricular valves, and the roots of the aorta and pulmonary trunk. It is shown that there is a limited amount of data in the literature regarding the sizes and positions of nodules on the semilunar leaflets of the aortic and pulmonary valves. The article focuses on the prevalence of openings and their morphometric characteristics in the semilunar leaflets of the studied valves. Histological features of the semilunar leaflets are presented, which include thickening and changes in cellular and fibrous composition depending on the age of the individual.
A clumped isotope calibration of coccoliths at well-constrained culture temperatures for marine temperature reconstructions
Authors: Clark Alexander J. , Torres-Romero Ismael , Jaggi Madalina , Bernasconi Stefano M. , Stoll Heather M.
Published: September 2024

Abstract. Numerous recent studies have tested the clumped isotope (Δ47) thermometer on a variety of biogenic carbonates such as foraminifera and bivalves and showed that most follow a common calibration. However, there may be a difference between biogenic-carbonate-based calibrations and the most recent inorganic carbonate calibrations that are assumed to have formed close to isotopic equilibrium. Biogenic calibrations such as those based on foraminifera from seafloor sediments suffer from uncertainties in the determination of the calcification temperatures. Therefore, well-constrained laboratory cultures without temperature uncertainty can help resolve these discrepancies. Although the sample size requirements for a reliable Δ47 measurement have decreased over the years, the availability and preservation of many biogenic carbonates are still limited and/or require substantial time to be extracted from sediments in sufficient amounts. Coccoliths, on the other hand, are abundant and often well-preserved in sediments, and they are a potential interesting target for palaeoceanography. We thus determined the Δ47–temperature relationship for coccoliths due to their relative ease of growth in the laboratory. The carbon and oxygen isotopic compositions of coccolith calcite have limited use in palaeoenvironmental reconstructions due to physiological effects that cause variability in the carbon and oxygen isotopic fractionation during mineralization. However, the relatively limited data available suggest that clumped isotopes may not be significantly influenced by these effects. We cultured three species of coccolithophores under controlled carbonate system conditions with CO2(aq) concentrations between 5 and 45 µM, pH between 7.9 and 8.6 units, and temperatures between 6 and 27 °C. Our well-constrained results agree with a previous culture study that there are no apparent species- or genus-specific vital effects on the Δ47–temperature relationship in coccolithophores despite significant deviations from equilibrium in the C and O isotopic composition. We find that while varying environmental parameters other than temperature does not have a significant effect on Δ47, changing the parameters yields coccolith Δ47–temperature calibrations that agree within 1.2 ppm. Our coccolith-specific Δ47–temperature calibration with well-constrained temperatures shows a consistent, positive offset of 2–3 °C to the inorganic carbonate calibrations, which point to as yet unknown coccolith-specific disequilibrium effects. Thus, we suggest the use of our coccolith-specific calibration for further coccolith palaeoceanographic studies and that calibrations derived from laboratory-grown biogenic carbonates are desirable to reinforce the confidence of clumped-isotope-based temperature reconstructions in palaeoceanography.
Assimilation of volcanic sulfur dioxide products from IASI and TROPOMI into the chemical transport model MOCAGE: case study of the 2021 La Soufrière Saint-Vincent eruption
Authors: Bacles Mickaël , Améric Jonathan , Guidard Vincent
Published: September 2024

Abstract. Sulfur dioxide emitted during volcanic eruptions can be hazardous for aviation safety. As part of their activities, the Volcanic Ash Advisory Centres (VAACs) are therefore interested in the real-time atmospheric monitoring of this gas. A recent development aims at improving the forecasts of volcanic sulfur dioxide quantities made by the MOCAGE chemistry transport model. For this purpose, observations from both TROPOMI and IASI (B and C) instruments located on separate polar orbiting satellites are assimilated in the model. These sulfur dioxide measurements are based on the eruption event of the La Soufrière Saint-Vincent volcano in April 2021. Observations from the OMI instrument are considered as validation data. The resulting assimilation experiments show that the combined assimilation of IASI and TROPOMI observations always leads to a better forecast compared to the independent assimilation of data from each instrument. Sulfur dioxide atmospheric field forecasts are better when the available observations are numerous and cover a long time window.
Electrical resistance tomography for sediment depth modeling in Croatia’s Paleolithic rock shelter & cave sites
Authors: Becker Rory J. , Janković Ivor , Karavanić Ivor , Ahern James C.M. , Komšo Darko , Vidas Lia , Banda Marko
Published: September 2024

Archaeological investigations in cave and rock shelter environmentspresent researchers with a unique set of challenges.Sediment depth modeling within cave or rock shelter sites aidsresearchers in placing excavations in productive locations. Electricalresistance tomography (ERT) is utilized more frequently inarchaeology over the last ten to fifteen years and is well suitedto modeling sediment depth profiles. However, its application toarchaeological cave and rock shelter sites is somewhat limiteddue to space restrictions for data collection as compared to openair sites. Presented here are results from 2014 – 2023 where ERTrory j. becker et al: electrical resistance tomography for sediment depth modeling in croatia’s paleolithic rock shelter...was incorporated into the research design on a series of projectsinvestigating Paleolithic cave & rock shelter sites in the AdriaticRegion of Croatia. The technique shows potential for continueduse in these environments though there are limitations to its applicabilityin these environments.
Kur’an’da İzzet Kavramının Anlam Derinlikleri ve Bağlamsal Kullanımları
Authors: Okuyucu Ömer
Published: September 2024

The concept of izzet in the Qur'an is addressed in both positive and negative contexts, encompassing two main meanings. The first refers to the exalted and true izzet attributed to Allah, His Messenger, and the believers; the second refers to the condemned false izzet associated with disbelievers, hypocrites, and polytheists. The term izzet appears in eleven instances in the Qur'an and, including its related verbal and nominal forms, occurs in a total of 110 verses. Among these, the attribute "Aziz" is mentioned in 99 verses, denoting Allah’s majesty and His supremacy over all things. In a few verses, izzet is also used in the sense of condemned arrogance and pride associated with disbelievers. This article aims to analyze the different meanings of the concept of izzet as it appears in the Qur'an, exploring both its linguistic and terminological definitions. It examines izzet’s etymological roots, its usage in classical Arabic dictionaries, and how it conveys different meanings depending on the context of the Qur'anic verses. Additionally, the study highlights the distinction between the positive izzet attributed to Allah, His Messenger, and the believers, and the negative izzetassociated with the arrogance and stubbornness of disbelievers and hypocrites. For believers, izzet is seen as a high moral quality, symbolizing loyalty and submission to Allah. Conversely, when izzet is combined with arrogance and pride, it becomes a condemned trait in the Qur'an. This study aims to elucidate the depth and breadth of the concept of izzet within the Qur'anic context, providing insight into how believers should properly understand and embody this concept. Key Words: Tafsir, Quran, Quranic Concepts, Praised Honor, Blamed Honor
¿Se puede obtener una puntuación global de ansiedad y depresión a partir de la Patient Health Questionnaire (PHQ-4) en población peruana que ha experimentado la muerte de un ser querido? Soporte empírico para un modelo unidimensional o de dos dimensiones
Authors: Carbajal-León Carlos , Caycho-Rodríguez Tomás , Yupanqui-Lorenzo Daniel E. , Lino-Cruz Christopher , Cabrera-Orosco Isabel , Ventura-León José , Vilca Lindsey W. , Reyes-Bossio Mario , Córdova-Robles Christian
Published: September 2024

Introducción: A nivel mundial, la ansiedad y la depresión figuran como los trastornos mentales más frecuentes, tanto en entornos clínicos como en la población en general. El Patient Health Questionnaire-4 es el instrumento de acceso libre más utilizado para evaluar la ansiedad y depresión tanto en entornos clínicos como comunitarios. Objetivo: El estudio tiene como objetivo evaluar las evidencias psicométricas del Patient Health Questionnaire (PHQ-4). Método: Participaron 1015 individuos peruanos entre 18 y 69 años (M=26.4, DE=9.93, 58.6% mujeres) que experimentaron la muerte de un ser querido. Se utilizaron técnicas derivadas de la Teoría Clásica de los Test y la Teoría de Respuesta al Ítem (IRT). Resultados: Se probaron tres modelos: unidimensional (CFI = 0.989; TLI = 0.966; RMSEA = 0.075), el de dos factores (CFI = 1.000; TLI = 1.000; RMSEA = 0.000) y el modelo bifactor el cual no convergió. El modelo de dos factores fue el que más se aproximó a un modelo perfecto. La confiabilidad, evaluada mediante el coeficiente omega, fue adecuada tanto para el modelo unidimensional (? = 0.88) como para el de dos factores (?ansiedad = 0.83; ?depresión = 0.78). El análisis por IRT indicó que, los ítems del PHQ-4 son adecuados indicadores que pueden discriminar entre quienes presentan o no los rasgos de ansiedad y depresión. Respecto a la relación entre el PHQ-4 y el duelo pandémico, tanto el modelo unidimensional (como el de dos factores demostraron índices de ajuste adecuados. Se demostró que el modelo unidimensional y el de dos factores son invariantes según el género y la edad. Conclusión: A pesar de que el modelo de un factor y dos factores correlacionados muestran adecuados índices de ajuste, el segundo tuvo un mejor ajuste. Además, este modelo presentó adecuada fiabilidad, discriminación y relación significativa con el duelo disfuncional.
The Effect of Liquid Nitrogen Administration on the Number of Chondrocytes in Male Rattus norvegicus of Wistar Strain
Authors: Persada Isma Satria Pandu , Irsan Istan Irmansyah , Phatama Krisna Yuarno
Published: September 2024

Introduction: This study investigates the impact of liquid nitrogen administration on histology and chondrocyte count in experimental animal cartilage, highlighting the limited benefits of cryosurgery on cartilage, a common treatment in orthopedics and skeletal muscle injuries.
Methods: The research design in this study was a random sampling experimental test on white male rats (Rattus norvegicus). Experimental animals that met the inclusion criteria were randomly divided into four groups: the control group and three groups that received different durations of liquid nitrogen administration (one, five, and ten minutes). Furthermore, an evaluation of the histology and the number of chondrocytes of the experimental animals was carried out and analyzed by statistical tests using SPSS 26.0.
Results: The One-way ANOVA analysis showed a significant difference in chondrocytes in the liquid nitrogen group compared to the control group. Furthermore, the results of the Tukey test showed that giving liquid nitrogen for 5 minutes and 10 minutes significantly reduced the number of chondrocytes in experimental animals. There was a negative correlation between liquid nitrogen administration and chondrocytes duration.
Discussion: Mechanical destruction of cells, including chondrocytes, occurs because the extreme temperature differences of liquid nitrogen can freeze the cells, becoming an ice crystal that can impair the physical structure of cells and membranes.
Conclusion: Liquid nitrogen administration significantly impacts chondrocyte levels in Rattus norvegicus strain cartilage, with duration negatively correlated with chondrocyte levels, suggesting a decrease with longer administration.

Keywords: cryosurgery, chondrocytes, neoplasm
The Effect of Functional Male Broodstock Sex Ratio on Fertilization and Hatching Rate of Climbing Perch (Anabas testudineus Bloch)
Authors: . Bunasir , . Slamat , Ansyari Pahmi
Published: September 2024

One approach to optimizing the effectiveness of functional male broodstock is by using different sex ratios during the spawning of climbing perch. This study aimed to analyze the effect of sex ratio on the fertilization and hatching rate of climbing perch. The main research was conducted at the Freshwater Aquaculture Research Center, Mandiangin, South Kalimantan. A Completely Randomized Design with 4 treatments and 3 replicates was employed. The research parameters were fertilization and hatching rate of the eggs. The effect of sex ratio on fertilization and hatching rate showed that the highest fertility rate was 94.40% in Treatment C (1:3 ratio), and the best hatching rate was 99.44% in Treatment B (1:2 ratio).

Keywords: Climbing Perch, Sex Ratio, Fertility, Hatching Rate
Development of Plant Reproduction E-Module with Sets (Science, Environment, Technology, and Society) Insight to Improve Learning Outcomes of Students of Grade IV of Wonorejo 04 Elementary School, Semarang Regency
Authors: Selvyana Kurnia , Sunarso Ali , Setiawan Deni
Published: September 2024

This research was conducted based on the results of observations and interviews with teachers in the teaching and learning process, and many teachers have yet to use teaching materials in the form of E-modules. This study aims to develop teaching materials for E-modules for SETS-based plant development for grade IV of Elementary Schools to improve the learning outcomes of elementary school students. The research method used is the research and development (R&D) method with the Borg & Gall development model with ten stages. This research was conducted with small-scale testing in grade IV of SDN Wonorejo 0 with 30 students and large-scale testing in grade V of SDN Wonorejo 04, Semarang Regency, with 30 students. Data and collection techniques in this study include interviews, questionnaires, document data, and test questions for validity, reliability, difficulty level, and discrimination. The study results show that the feasibility of developing an E-module for SETS-based plant development is developed according to the characteristics and needs of students and teachers. For the feasibility of the E-module, the material expert obtained a score of 95% with very feasible criteria. Then, the media expert validator obtained a score of 100% with very feasible criteria. The language expert validator obtained a score of 93% with very feasible criteria. Both the effectiveness of the E-module based on the n-Gain results of 0.53 with moderate criteria and the effectiveness interpretation obtained a score of 89.82 with quite effective criteria. So, the developed teaching materials effectively support elementary school students' learning outcomes.

Keywords: E-modules, SETS, Learning Outcomes and Primary Schools.
Blood Culture Contamination in a Busy Emergency Ward of a Tertiary Care Hospital in Kolkata
Authors: Bandyopadhyay Syamasis , Dastidar Aheli Ghosh , Chandra Sandip Kumar
Published: September 2024

Introduction: Blood culture contamination (BCC) is a serious clinical problem which leads to consequences like initiation or prolongation of antibiotic therapy, complications associated with antibiotic use and prolongation of hospital stay adding to healthcare expenses etc. BCC occurs mostly during sample collection. A Survey of blood collection technique in hospital showed that blood culture sample collection into BACT ALERT bottles by plain syringes results in multiple surface contact thereby increasing contamination rate. To overcome this problem a set of new blood culture vacutainer holder was introduced so that blood could directly be collected into blood culture bottles without any intermediate contact. This audit was done to objectively evaluate whether introduction of this device reduces BCC rates in a hospital.
Methods: Data of BCC rate in blood culture samples collected in emergency was assessed for 1 month period before and after introduction of new blood culture holders.
Results: BCC rate before and after introduction of new holders were 25.33% and 9.57% respectively. The results thus demonstrated a 62.21% reduction in blood culture contamination rate. Chi Square test showed a significant reduction of BCC rate after this improvisation of sample collection technique. (p value 0.001)
Conclusion: Introduction of the improvised blood culture collection technique with special holder objectively reduced BCC rates without any significant increase in cost. Findings of this clinical audit instils hope that the wider usage of this device can bring down BCC rates significantly, while at the same time ensuring convenience of collection and increasing needle safety.

Keywords: Blood Culture Contamination, contaminants, Vacutainer holder .