bluuebunny/crossref_metadata_2025 huggingface dataset:
Pedagogía de la confianza: una estrategia para generar ambientes escolares de paz
Authors: Pinilla Quiñones Ninfa , Mendieta González María Del Carmen
Published: October 2017

La convivencia escolar es un tema recurrente desde las últimas décadas del siglo XX y comienzos del siglo XXI, en razón de los altos índices de violencia y su repercusión negativa en el aprendizaje y la construcción de habilidades sociales y comunicativas de los estudiantes. Por ello, en la institución educativa Liceo Nacional José Joaquín Casas, sede General Santander, de Chiquinquirá, entre los años 2011 a 2013 se desarrolló el proyecto Pedagogía de la Confianza, orientado al manejo y posible solución de los constantes conflictos que se presentaban entre los niños y las niñas de los grados tercero, cuarto y quinto, muchas veces resueltos de forma violenta. Dicha experiencia, abordada como un estudio de caso, fue sistematizada para: 1) dar cuenta de la praxis pedagógica en contextos locales, que en muchas ocasiones no es reconocida por la comunidad ni por el Estado; 2) identificar y comprender las acciones que aportan en la resolución pacífica de conflictos, así como en la cimentación de una cultura del buen trato, y 3) visibilizar el uso de narrativas aplicadas con estudiantes, docentes y directivos de la institución, con resultados satisfactorios.
Propuesta para gestionar la responsabilidad social empresarial en las tiendas “Juan Valdez” en Colombia
Authors: Morales Rey Sandra Janneth , Vargas Ordoñez Marcela
Published: October 2017

En la actualidad las organizaciones están bajo precisa observación de sus consumidores, que son rigurosos y buscan más allá de un buen producto o servicio. Las organizaciones se ven en la obligación de contribuir al desarrollo sostenible con la mejora continua de sus procesos, la gestión de la inocuidad y en especial con prácticas de responsabilidad social. Este artículo presenta el estudio realizado a las tiendas Juan Valdez con el fin de elaborar una propuesta para gestionar la responsabilidad social en Colombia según la guía internacional ISO 26000. El estudio aborda las tiendas Juan Valdez de Colombia en el marco de estrategias competitivas enfocadas en la responsabilidad social empresarial (RSE), donde se percibe la ausencia de un diagnóstico y de resultados reales en la organización. Para determinar los anterior, se plantea la estructura de dos instrumentos con base en lineamientos de la RSE; el diseño de estos instrumentos permite evaluar y contrastar la percepción de los trabajadores respecto a la ejecución real en las tiendas Juan Valdez. Además, se contrasta la estrategia de la compañía, con los principios y temas de responsabilidad social según la guía ISO 26000; por último, se caracteriza el funcionamiento de los principios y temas de RSE. El resultado evidencia que la compañía presenta ausencia de conocimiento de los funcionarios en relación con la forma como se debe gestionar la responsabilidad social como eje articulador de todas sus acciones. Adicionalmente resultan dos componentes con oportunidad de mejora: el desempeño ambiental y el social hacia la comunidad.
Žvelgiant žuvies akimi: posthumanistinė perspektyva Lucieno Castaing-Tayloro ir Véréna’os Paravelos filme "Leviatanas"
Authors: Chkhaidze Irina
Published: October 2017

This article conceptualises Lucien Castaing-Taylor and Véréna Paravel’s experimental documentary Leviathan (2012) using Niklas Luhmann’s observation theory and Cary Wolfe’s writing on posthumanism which, significantly influenced by Luhmann’s attack on anthropocentrism in social theory, questions the importance of human agency for social and psychic systems. Leviathan, I argue, engenders perspectives drawn from visual culture that enable a rethinking of hierarchical humanist ethics based on species membership, contributing to posthumanist critical discourse.Leviathan offers a radically non-anthropocentric take on the topic of industrial fishing, presented via innovative use of camera placements and cinematic points of view. Unpredictable camera movements involving contingent framing and angles generate an open-ended work not tied to the human gaze. Shooting from a caught marine animal’s point of view forces the viewer to assume an unexpected perspective. To analyse this particular perspective, I turn to Luhmann’s theories about an observation not tied to human subjectivity, where the subject of observation is simultaneously an object, and where the external world is equally inaccessible to humans and nonhumans alike. In this schema, present in any observation is a constitutive blindness that can only be seen by another observer, but it is this very blindness which makes the observation possible.
Politinis išsivadavimas ir „jautrusis subjektas“: lakaniško kairuoliškumo dilemos
Authors: Morgan David
Published: October 2017

The purpose of this paper is to tentatively explore the plausibility of the application of aspects of Lacanian psychoanalytic theory (and practice) to the purposes of Leftist political discourse. We live in an era when the forces of conservative political reaction are increasingly coming to the fore across Western democracies. In many Western states the reactionary right is in the ascendency: while the Left seems largely mired in political disarray and introspective impotence. Might the theories and insights of Jacques Lacan offer the Left some hope of a revivified intellectual and ideological cogency? This paper will attempt to draw together themes and ideas arising from recent scholarship within the field of Lacanian studies so as to explore ways in which the psychoanalytic theory and practice of Lacan might be utilised in the service of contemporary Leftist politics. In particular recent Lacanian scholarship has suggested that the provocative and fertile work of the scholar Slavoj Žižek might provide the foundation for just such a Lacanian Leftist renaissance. Contrary to this, this paper suggests that psychoanalysis itself should perhaps be regarded as a fundamentally tragic mode of thought – which might thus be intrinsically unsuited to the emancipatory purposes of the Left. Instead the paper will suggest that Lacanian theory might best serve the Left on a tactical level: as a radical interpretative technique whereby the texts and discourses of bourgeois cultural hegemony may be subjected to revivified critical scrutiny.
Human resource factors associated with workplace safety and health education of small manufacturing businesses in Korea
Authors: Park Kyoung-Ok
Published: October 2017

Objectives

Human resources (HR) are essential indicators of safety and health (SH) status, and HR can be key sources of workplace safety management such as safety and health education at work (SHEW). This study analyzed significant HR factors associated with SHEW of small manufacturing businesses in Korea.

Methods

The secondary data of the 2012 Korea Occupational Safety and Health Trend Survey were used to achieve this research purpose. A total of 2,089 supervisors or managers employed in the small manufacturing businesses completed the interview survey. Survey businesses were selected by multiple stratified sampling method based on industry code, business size, and region in Korea. The survey included workplace characteristics of HR and SHEW.

Results

SHEW was significantly related to business size, occupational injury incidence in the previous year, foreign and elderly worker employment, presence of site supervisors, and presence of SH committees (p <.05). SHEW for office workers, non-office workers, and newcomers was associated with business size, presence of site supervisors, and presence of SH committees in logistic regression analysis (p < .001) . Businesses with 30-49 workers conducted SHEW 3.64 times more than did businesses with 5 to fewer than 10 workers. The companies that had occupational injuries in the previous year conducted SHEW 1.68 times more than the others. The businesses that had site supervisors and committees conducted SHEW 2.30 and 2.18 times more, respectively, than others.

Conclusions

Site supervisors and SH committees were significant HR factors that improved SHEW in small manufacturing businesses.
A Newborn With Abdominal Pain
Authors: Alwan Riham , Drake Meredith , Gurria Juarez Juan , Emery Kathleen H. , Shaaban Aimen F. , Szabo Sara , Sobolewski Brad
Published: October 2017

A previously healthy 3-week-old boy presented with 5 hours of marked fussiness, abdominal distention, and poor feeding. He was afebrile and well perfused. His examination was remarkable for localized abdominal tenderness and distention. He was referred to the emergency department in which an abdominal radiograph revealed gaseous distention of the bowel with a paucity of gas in the pelvis. Complete blood cell count and urinalysis were unremarkable. His ongoing fussiness and abnormal physical examination prompted consultation with surgery and radiology. Our combined efforts ultimately established an unexpected diagnosis.
A 3-Month-Old With Failure to Thrive and Persistent Vomiting
Authors: Heneghan Julia A. , Moses Jonathan , Lidsky Karen , Kim Anne , DeSapri Melani , Stephans Allayne
Published: October 2017

A 3-month-old boy was admitted from his pediatrician’s office for failure to thrive and vomiting. On admission, he weighed barely more than his birth weight and was cachectic with muscle wasting. His abdomen was grossly distended but soft and nontender. A trial of nasogastric feeds resulted in a worsening of his clinical status. He was transferred to the ICU, and diagnostic imaging was concerning for a distal bowel obstruction. Surgical pathology revealed a surprising diagnosis, which is described in detail in the following case.
Comparison of brain connectivity between Internet gambling disorder and Internet gaming disorder: A preliminary study
Authors: Bae Sujin , Han Doug Hyun , Jung Jaebum , Nam Ki Chun , Renshaw Perry F.
Published: October 2017

Background and aims

Given the similarities in clinical symptoms, Internet gaming disorder (IGD) is thought to be diagnostically similar to Internet-based gambling disorder (ibGD). However, cognitive enhancement and educational use of Internet gaming suggest that the two disorders derive from different neurobiological mechanisms. The goal of this study was to compare subjects with ibGD to those with IGD.

Methods

Fifteen patients with IGD, 14 patients with ibGD, and 15 healthy control subjects were included in this study. Resting-state functional magnetic resonance imaging data for all participants were acquired using a 3.0 Tesla MRI scanner (Philips, Eindhoven, The Netherlands). Seed-based analyses, the three brain networks of default mode, cognitive control, and reward circuitry, were performed.

Results

Both IGD and ibGD groups demonstrated decreased functional connectivity (FC) within the default-mode network (DMN) (family-wise error p < .001) compared with healthy control subjects. However, the IGD group demonstrated increased FC within the cognitive network compared with both the ibGD (p < .01) and healthy control groups (p < .01). In contrast, the ibGD group demonstrated increased FC within the reward circuitry compared with both IGD (p < .01) and healthy control subjects (p < .01).

Discussion and conclusions

The IGD and ibGD groups shared the characteristic of decreased FC in the DMN. However, the IGD group demonstrated increased FC within the cognitive network compared with both ibGD and healthy comparison groups.
Going Beyond Classroom Learning: Acquiring Cultural Knowledge via On-Line Newspapers and Intercultural Exchanges via On-Line Chatrooms
Authors: Lee Lina
Published: October 2017

The Internet is increasingly considered as an instructional tool for foreign language learning both within and beyond classroom learning. This article reports a pilot study on the use of a combination of Internet technologies--on-line newspapers and on-line chatrooms--to enhance the learning of advanced Spanish students. The goal of the project was (a) to create opportunities for students to read authentic materials and gain cultural knowledge via on-line newspapers, (b) to enhance intercultural exchanges via on-line chatrooms, and (c) to improve students' writing and speaking skills as well as promote collaborative learning among students. The positive results of the study indicate that foreign language teachers could well explore and experiment with the application of combined Internet resources for advanced language students.
DaRT: A CALL System to Help Students Practice and Develop Reasoning Skills in Choosing English Articles
Authors: Yoshii Rika , Milne Alastair
Published: October 2017

DaRT is a Computer Assisted Language Learning (CALL) system for helping English as a Second/Foreign Language students master English articles. The system uses a diagrammatic reasoning tool described in previous studies (Yoshii, 1997, 1998) to present communicative contexts for exercises in choosing appropriate articles. These diagrams make explicit the "intent-assumption" factors involved in article choice for many situations and permit students and teachers to discuss these factors without relying on English language explanations which depend on concepts foreign to most Asian students. DaRT can generate numerous exercise sentences, provide help based on student interactions, and choose the next exercise based on student performance. DaRT functions, therefore, as a tutorial to help students acquire the skills necessary for analyzing and applying the "intent-assumption" factors in choosing English articles. This article describes the major stages of the project, provides details of the system components, and concludes with the results of an evaluation of the system by Japanese students.
On Disciplinary Finitude
Authors: Schnapp Jeffrey T.
Published: October 2017

The year 2008 was one of fruitful disjunctions. I spent the fall teaching at Stanford but commuting to the University of California, Los Angeles, to cochair the inaugural Mellon Seminar in Digital Humanities. During the same period, I was curating—at the Canadian Center for Architecture, in Montreal—an exhibition devised to mark the centenary of the publication of “The Founding Manifesto of Futurism,” by Filippo Tommaso Marinetti. Whereas other centennial shows (at the Centre Pompidou, in Paris, and at the Palazzo Reale, in Milan) sought to celebrate the accomplishments and legacies of Marinetti's avant-garde, the Canadian exhibition,Speed Limits, was critical and combative in spirit, more properly futurist (though thematically antifuturist). It probed the frayed edges of futurism's narrative of modernity as the era of speed to reflect on the social, environmental, and cultural costs. An exhibition about limits, it looked backward over the architectural history of the twentieth century to look forward beyond the era of automobility.
Boundaries of Culture
Authors: Appiah Kwame Anthony
Published: October 2017

So begins Constantine Cavafy's classic poem of November 1898, “Waiting for the Barbarians,” in Edmund Keeley and Philip Sherrard's assured translation. Cavafy was a writer who tested all manner of boundary conditions. His every identity came with an asterisk. He was a Greek who never lived in Greece. A government clerk of Greek Orthodox upbringing, in a tributary state of a Muslim empire, he spent his evenings on foot, looking for pagan gods in their incarnate, carnal versions. He was a poet who resisted publication, save for broadsheets he circulated among close friends; a man whose homeland was a neighborhood, and a dream. Much of his poetry is a map of Alexandria overlaid with a map of the classical world—modern Alexandria and ancient Athens—as Leopold Bloom's Dublin neighborhood underlies Odysseus's Ithaca. And I conjure Cavafy because, as I want to persuade you, he is representative precisely in all his seeming anomalousness.
Reading the Red Bull Sublime
Authors: McCARTHY ANNE C.
Published: October 2017

The aesthetic of the sublime has long been associated with the language of elevation and height. Activities such as mountain climbing offer a physical correlative to this discourse. In these cases, the sublime is associated with a high point or summit, and the process of descent is minimized or erased. By contrast, what I call the Red Bull sublime—named for the energy drink company that claims to “give you wings”—uses technological innovation to draw attention to the aesthetic pleasures of falling. Taking Felix Baumgartner's 2012 space jump as its paradigmatic example, this essay elaborates the central features of the Red Bull sublime, connecting it with a Romantic tradition, represented here by Samuel Taylor Coleridge and John Keats, of peering over the edge of the abyss.
Sameness and the Poetics of Nonrelation: Andrew Marvell's “The Garden”
Authors: Netzley Ryan
Published: October 2017

Andrew Marvell's “The Garden” foregrounds the role of subtraction in aesthetic creation and seeks to imagine sameness independent of metaphor, similarity, and relation. The poem employs a subtractive poetics that challenges modern presuppositions about the networked, connected essence of literature. It also points to the critical limitations of recent accounts of surface and formalist reading, both of which still present poetry as productive, especially insofar as it heightens attention. For Marvell, in contrast, the value of lyric resides in the ways in which it challenges the dialectical notion of creative destruction and, instead, conceives of an annihilation that does not transform into its more respectable opposite. “The Garden,” then, shows that we and our students are overburdened with connection—that there is too much relation, not too little—and that the function of poetry is to dismantle these links in the interest of creativity.
“The Figure in the Carpet”
Authors: Armstrong Nancy , Montag Warren
Published: October 2017

Of Franco Moretti's masterworks of literary history and theory, why is it the loosely assembled collection of occasional pieces Distant Reading that has captured the literary critical spotlight? Why now, just when enrollments in the humanities are plummeting, new technologies for storing and distributing information are revolutionizing interpersonal communication and scientific methods, and global is well on its way to replacing interdisciplinary as the descriptor favored by university administrators? Moretti is not alone in attempting to reconfigure a discipline that tends to favor the singular text and national literary traditions for a generation of students who apparently could not care less about either. In his effort to adapt literary history and form to the conditions of globalization that make them seem irrelevant, he asks us to abandon our obsessive focus on canonical texts—to start instead considering how certain forms of literature made the quantum leap from nation to world and what formal changes they underwent in doing so. This project he warns, will require us to “unlearn” how to read a literary text and to question the assumption that “world literature” is an object to be known: “We must think of it as a problem that asks for a new critical method” (46). He famously exposes this problem by staging various encounters between literary form and quantitative analysis.
Beyond Darwinian Distance: Situating Distant Reading in a Feminist Ut Pictura Poesis Tradition
Authors: Rhody Lisa Marie
Published: October 2017

The challenge facing “distant reading” has less to do with Franco Moretti's assertion that we must learn “how not to read” than with his implication that looking should take the place of reading. Not reading is the dirty open secret of all literary critics-there will always be that book (or those books) that you should have read, have not read, and probably won't read. Moretti is not endorsing a disinterest in reading either, like that reported in the 2004 National Endowment for the Arts' Reading at Risk, which notes that less than half the adult public in the United States read a work of literature in 2002 (3). In his “little pact with the devil” that substitutes patterns of devices, themes, tropes, styles, and parts of speech for thousands or millions of texts at a time, the devil is the image: trees, networks, and maps-spatial rather than verbal forms representing a textual corpus that disappears from view. In what follows, I consider Distant Reading as participating in the ut pictura poesis tradition-that is, the Western tradition of viewing poetry and painting as sister arts-to explain how ingrained our resistances are to Moretti's formalist approach. I turn to more recent interart examples to suggest interpretive alternatives to formalism for distant-reading methods.
Rare Tumor Clinic: The University of California San Diego Moores Cancer Center Experience with a Precision Therapy Approach
Authors: Kato Shumei , Kurasaki Kellie , Ikeda Sadakatsu , Kurzrock Razelle
Published: October 2017

Background

Patients with rare tumors may lack approved treatments and clinical trial access. Although each rare tumor is uncommon, cumulatively they account for approximately 25% of cancers. We recently initiated a Rare Tumor Clinic that emphasized a precision medicine strategy.

Materials and Methods

We investigated the first 40 patients presenting at the Rare Tumor Clinic. Next-generation sequencing (NGS) of tissue and plasma-derived, circulating-tumor DNA (ctDNA), and protein markers were assessed.

Results

Median age was 58 years (range, 31–78 years); 70% (28/40) were women; median number of previous systemic therapies was 2 (range 0–7). The most common diagnoses were sarcoma (n = 7) for solid tumors and Erdheim-Chester disease (n = 5) for hematologic malignancies. Twenty distinct diagnoses were seen. Examples of ultrarare tumors included ameloblastoma, yolk sac liver tumor, ampullary cancer, and Castleman's disease. Altogether, 32 of 33 patients (97%) with tissue NGS and 15 of 33 (45%) with ctDNA sequencing harbored ≥1 alteration. Overall, 92.5% of patients (37/40) had ≥1 actionable target based on either genomic (n = 32) or protein (n = 27) markers. In total, 52.5% (21/40) received matched therapy; 52.4% (11/21) achieved stable disease (SD) ≥6 months (n = 3), partial remission (PR; n = 6), or complete remission (CR; n = 2). Matched therapy resulted in significantly longer progression-free survival compared with last prior unmatched therapy (hazard ratio 0.26, 95% confidence interval 0.10–0.71, p = .008).

Conclusion

Identifying genomic and protein markers in patients with rare/ultrarare tumors was feasible. When therapies were matched, >50% of patients attained SD ≥6 months, PR, or CR. Further precision medicine clinical investigations focusing on rare and ultrarare tumors are urgently needed.

Implications for Practice

Although rare tumors are infrequent by definition, when all subtypes of rare cancers are combined, they account for approximately 25% of adult malignancies. However, patients with rare tumors may lack approved treatments and clinical trial access. This paper describes an institutional a Rare Tumor Clinic focused on a precision medicine strategy. Performing genomics and protein analyses was feasible amongst patients with rare cancers. Over 50% of patients attained SD ≥6 months, PR, or CR when they received matched therapy (genomically targeted and/or immunotherapy). Further studies investigating the efficacy of the precision therapy approach among rare tumors are warranted.
Efficacy of Prophylactic Treatment for Oxycodone-Induced Nausea and Vomiting Among Patients with Cancer Pain (POINT): A Randomized, Placebo-Controlled, Double-Blind Trial
Authors: Tsukuura Hiroaki , Miyazaki Masayuki , Morita Tatsuya , Sugishita Mihoko , Kato Hiroshi , Murasaki Yuka , Gyawali Bishal , Kubo Yoko , Ando Masahiko , Kondo Masashi , Yamada Kiyofumi , Hasegawa Yoshinori , Ando Yuichi
Published: October 2017

Background

Although opioid-induced nausea and vomiting (OINV) often result in analgesic undertreatment in patients with cancer, no randomized controlled trials have evaluated the efficacy of prophylactic antiemetics for preventing OINV. We conducted this randomized, placebo-controlled, double-blind trial to evaluate the efficacy and safety of prophylactic treatment with prochlorperazine for preventing OINV.

Materials and Methods

Cancer patients who started to receive oral oxycodone were randomly assigned in a 1:1 ratio to receive either prochlorperazine 5 mg or placebo prophylactically, given three times daily for 5 days. The primary endpoint was the proportion of patients who had a complete response (CR) during the 120 hours of oxycodone treatment. CR was defined as no emetic episode and no use of rescue medication for nausea and vomiting during 5 days. Key secondary endpoints were the proportion of patients with emetic episodes, proportion of patients with moderate or severe nausea, quality of life, and proportion of treatment withdrawal.

Results

From November 2013 through February 2016, a total of 120 patients were assigned to receive prochlorperazine (n = 60) or placebo (n = 60). There was no significant difference in CR rates (69.5% vs. 63.3%; p = .47) or any secondary endpoint between the groups. Patients who received prochlorperazine were more likely to experience severe somnolence (p = .048).

Conclusion

Routine use of prochlorperazine as a prophylactic antiemetic at the initiation of treatment with opioids is not recommended. Further research is needed to evaluate whether other antiemetics would be effective in preventing OINV in specific patient populations.

Implications for Practice

Prophylactic prochlorperazine seems to be ineffective in preventing opioid-induced nausea and vomiting (OINV) and may cause adverse events such as somnolence. Routine use of prophylactic prochlorperazine at the initiation of treatment with opioids is not recommended. Further research is needed to evaluate whether other antiemetics would be effective in preventing OINV in specific patient populations.
Seismic response of reduced scale stone masonry building
Authors: Rafi Muhammad Masood , Lodi Sarosh Hashmat , Qazi Saad Ahmed , Kumar Amit , Verjee Firoz
Published: October 2017

The results of shaking table tests of a one-third stone masonry building model have been presented in this paper. The model was subjected to four levels of acceleration–time history record of the 1940 El Centro earthquake. These levels include 75% (R75), 100% (R100), 125% (R125) and 150% (R150). The data relating to acceleration and displacement were recorded and analysed. The fundamental mode of vibration of the structure was observed at all the levels of ground acceleration that were employed. The in-plane walls at the first storey were severely damaged as the structure was subjected to the increasing levels of peak ground acceleration. The maximum structure response to the ground vibration was observed at the R100 level of acceleration–time history. The fundamental frequency of the model decreased from 9/s for the virgin structure to 1/s after the R150 test run, whereas the damping ratio increased from 4·88 to 29·77%. The idealised resistance curve of the tested model indicated a structure ductility of 2·18.
Use of loop diuretics in heart failure: Current aspects
Authors: Kurlykina N V , Seredenina E M , Orlova Yа A
Published: October 2017

Loop diuretics take the lead in the treatment of patients with symptomatic heart failure. Torasemide is the most effective and safe loop diuretic with the optimal pharmacokinetic profile, the additional properties associated with simultaneous blockade of the renin-angiotensin-aldosterone system and with the antiadrenergic effects of the drug, its positive impact on myocardial fibrosis and minimal severe potential negative effects. Sustained-release torasemide provides a more comfortable removal of excess liquid and does not deteriorate quality of life.
Non-vitamin K antagonist oral anticoagulants for heart diseases
Authors: Kondratieva T B , Popova L V , Bokarev I N
Published: October 2017

Non-vitamin K antagonist oral anticoagulants (NОАСs) are highly effective drugs that prevent venous thrombosis and stroke in atrial fibrillation. Their use has difficulties that are associated with the need for laboratory control and with the influence of many factors on the activity of these medications. The emerged direct oral anticoagulants have some advantages over NOACs. Nevertheless, there are a number of pathological conditions, in which NOACs remain first-line drugs. These include prosthetic mechanical heart valves, a glomerular filtration rate less than 60 mL/min/1.73 m2, and left atrial thrombus.
Impact of hyperglycemia on the results of percutaneous coronary interventions in patients with acute ST-segment elevation myocardial infarction
Authors: Bessonov I S , Kuznetsov V A , Potolinskaya Yu V , Zyrianov I P , Sapozhnikov S S
Published: October 2017

Aim. To investigate the impact of hyperglycemia on the results of percutaneous coronary interventions (PCIs) in patients with acute ST-segment elevation myocardial infarction (ASTEMI). Subjects and methods. A study group consisted of 511 patients with hyperglycemia (blood glucose level (BGL) ≥7.77 mmol/L) who underwent primary PCIs in the period from 2005 to 2015. A comparison group included 579 patients (BGL ≥7.77 mmol/L). Results. Assessment of the results of hospital interventions revealed that the mortality rates in patients with hyperglycemia proved to be higher than in those with normal BGL (6.5 and 2.6%, respectively; p=0.002). No differences were found in the rates of stent thrombosis (1 and 1.4%; p=0.541) and recurrent myocardial infarction (1.2 and 1.6%; p=0.591). Major adverse cardiac events, including death, recurrent infarction, and stent thrombosis, were more frequently determined in the hyperglycemic patients (7.6 and 4.3%; p=0.020). No-reflow phenomenon statistically significantly more frequently developed in the patients with hyperglycemia (6.8 and 3.3%; p=0.007). Binary logistic regression analysis showed that the presence of hyperglycemia served as an independent predictor of hospital mortality (odds ratio (OR) 2.6; 95% confidence interval (CI), 1.4 to 4.8; p=0.002). The application of a random probability sampling technique revealed that mortality remained statistically significantly higher in the hyperglycemic patients than in the normoglycemic individuals at admission (6.7 and 2.6%; р=0.011). Conclusion. PCIs in patients with ASTEMI and hyperglycemia are characterized by higher mortality rates and the risk of major adverse cardiac events. Admission hyperglycemia is an independent predictor of hospital mortality.
Role of AGTR1 A/C polymorphism in the development of atrial fibrillation
Authors: Kuskaeva A V , Nikulina S Yu , Chernova A A , Aksyutina N V , Kuskaev A P , Cherkashina I I
Published: October 2017

Aim. To investigate the AGTR1 A/C polymorphism associated with atrial fibrillation (AF) to form risk groups among patients who are prone to this disease. Subjects and methods. 90 probands with a confirmed diagnosis of AF and their 144 first-, second-, and third-degree relatives were examined. These families made up a study group. A control group was formed of 100 apparently healthy individuals without a history of cardiovascular diseases. Collection of medical history data and complaints, electrocardiography, electrocardiogram monitoring, as well as molecular genetic analysis, thyroid hormone tests were done in all the patients. Results. No statistically significant data on the correlation between the AGTR1 A/C polymorphism and the development of AF were obtained in any patient subgroup. The obtained results can be due to the genetic features of a Siberian population, which are dependent on climatic conditions and geographical location, and confirm that AF is a heterogeneous disease. Conclusion. There were no statistically significant differences between the patients in the study group and those in the control group. Our findings suggest the heterogeneity of AF and confirm its multifactorial nature.
Dry Swab Sampling and Transportation v1
Authors: Liu Chunan
Published: October 2017

Protocols for samping and shipping human skin swabs from clinics to lab.
Assembly with Megahit v4
Authors: E Thornton Jr James
Published: October 2017

Co-assembly using Megahit.
DEVELOPMENT OF THE BEVERAGE PRODUCTION IN MARKET CONDITIONS (ON THE EXAMPLE OF THE VOLYNSK REGION)
Authors: Sosnitsky Y. , Sagan J.
Published: October 2017

Purpose. The article is the disclosure of the functioning of the sugar-beet complex Volyn region in the current market conditions, the isolation of the main problems and prospects of the industry and its branches.
The methodological basis of the work is a systematic approach to the study of social and economic processes occurring in the sugar beet sector Volyn region. During the research used a number of methods, main of which are: theoretical generalization, comparison and analysis of system-structural analysis, mapping.
Research results. While Ukraine has transitioned to the market relations it was mentioned the decrease of sugar – beet’s acreage in Volyn region and this data was 11,300 hectares in 2005. It was collected 4,202,000 tones of sugar beet from this area. The reasons for the reduction of sugar beet crops is the lack of economic incentives sugar beet households, worsening their financial situation and logistical support, and lack of effective measures to protect domestic sugar market.
The main producers of sugar beet sector is the southern districts. The choic of sugar beet branch for agriculture concerns of the southern regions caused by the proximity of processing plants as transport factor is one of the most important when placing the industry and has a direct impact on profitability.
Processing link sugar-beet complex in the Volyn region includes two sugar factories, which in 2015 processed 4,204,000 tons of sugar beet and produced 63,4 00 tons of sugar.
The main problem of sugar beet complex is insufficient integration and weak links between sugar beet producers and processors. The main way to overcome this problem is to use cluster system of production.
Scientific novelty. Comprehensively reveals the current state sugar beet production in the Volyn region and analyzed the dynamics that characterized to him. The mapped schemes were created to reflect the regional differences of sugar heet production of the district that was researched.
The practical significance. Ways to improve the functioning of the proposed sugar-beet complex in the Volyn region can be used in the preparation of applications development in the region, Volyn Regional State Administration. Some provisions can be implemented in the educational process of the Faculty of Geography.
PRICING OF REGIONAL HOUSING MARKETS, THEORETICAL AND APPLIED ASPECTS
Authors: Zapototska V.
Published: October 2017

The article covers the theoretical and applied principles of price formation for housing within regional markets. In research process was found that the development of the regional housing market is subordinated to the action of regional development theories and general economic theories (cost and price).
Among the spatial theories the influence of theories of agriculture placing and industry, central places, geographical location of economy, the theories of “growth poles”, “diffusion of innovations”, “center-periphery theory”, “city-centrality”. Economic theories are theories which actually are based on market process, formation of free market and theories of market`s processes regulation. It is proved that such theories do joint influence on pricing and the pricing mechanisms. It is proved that such theories do common influence on price formation and the pricing mechanisms. It was found, that pricing is an objective process, for determining and establishing prices within the region, which occurs primarily at regional and local level, touching individual regional market and is subjected to regulation by the state.
It was established, that the formation of regional housing markets are too difficult process and are indicated by a large number of factors influencing to the processes of its formation. Through theoretical generalization, we identified six groups of factors that have a direct and indirect impact on supply and demand on the regional housing market.
To the first group of factors attributed territorial housing market factors, among which are selected location of the property, infrastructure providing of this territory and ecological situation. The second group of factors includes quality characteristics of housing, among which are: construction materials; working characteristics and wearing out; architectural and planning features of the property. The third group is represented by economic factors, which include income of population, income of developers or property developers; the overall level of development of a region or settlement; investment factor; mortgage factor speculative factor and construction industry development in general. Group of demographic-settlement factors include an assessment of the demographic situation, labor market in the region, migration processes, the system of settlement and security of this area. Legislative and legal factors manifested through the state and regional policy in the housing market, housing programs, taxation processes, lending insurance and in the housing market. Social and psychological factors include behavior and preferences of consumers, price expectations, seasonality, ethnic or religious characteristics of the region.
Here are presented the dynamics and confirmed differentiation in housing prices within the largest cities in Ukraine and in the city of Kyiv.
The reasons of genetic heterogeneity of Siberian whitefish Coregonus lavaretus pidschian in the Anabar river
Authors: Sendek Dmitry S. , Ivanov Eugenie V.
Published: October 2017

Background. A population genetic study of Siberian whitefish or pidschian Coregonus lavaretus pidschian Gmelin of the Anabar River (North-West Yakutia) has been done to study genetic structure of the species within a river system and for revealing its phylogeographic relations.

Materials and Methods. Five samples of pidschian from different parts of the river were analyzed for 30 isozyme loci.

Results and Discussion. The results has demonstrated a significant genetic heterogeneity of the species sampled from lower and middle reaches of the river (0.001 DN 0.056). The most likely reason for genetic differentiation of the species within the river system is a colonization of the watershed by independent phylogenetic lineages of whitefish. At present the phylogenetic lineages in Anabar River are presented by sympatric ecological forms of the species eastern-siberian whitefish and glacial-plains whitefish which maintain their reproductive isolation. The relationships of ecological forms of whitefish dwelling the Anabar River with other populations of the species in Siberia, and possible ways of penetration of discrete phylogenetic lineages of pidschian in the basin of studied river are discussed.

Conclusions. A genetic heterogeneity of whitefish from Anabar River should be taken into account while creating adequate intraspecific taxonomy and considered in conducting fisheries and environmental measures.
Assessment of the state of population gene pools of the slightly mobile animal species on the example of the land snail Bradybaena fruticum Müll. (Gastropoda, Pulmonata) based on the DNA markers
Authors: Snegin Eduard A. , Snegina Elena A.
Published: October 2017

Using the polymorphic DNA markers (RAPD and ISSR), the genetic structure was examined and the viability of 26 populations of the terrestrial gastropod Bradybaena (Fruticicola) fruticum Mll., most of which lives in the south of the Central Russian Upland, was estimated. Samples from Romania, the Urals and Vyatka regions for comparison were taken. In total, 1153 individuals were examined. The level of expected heterozygosity averaged He = 0.208 0.028, the Shannon index Ish = 0.320 0.039. The lowered level of variability, both actual and theoretically expected (estimated by the methods of Chao1-bc and 1st order jackknife) in groups of anthropogenically disturbed biotopes inhabiting the zones of industrial enterprises is noted. The indices of the genetic disunity of the populations were Fst = 0.298, Gst = 0.254, and the level of the gene flow Nm = 0.708. The cluster analysis and the Mantel correlation coefficient Rm = 0.024 showed the absence of a reliable relationship between the geographic and genetic distance between populations, which indicates the violation of the isolation model by distance and confirms the thesis advanced earlier that the urbanized forest-steppe landscape disrupts the natural migration processes, leads to the strong isolation and of the genetic drift in populations of snails. At the same time, the observed phenomenon of increasing the degree of subdivision of populations against the background of a decrease in the allelic diversity noted by us in many groups of bush snail can be regarded as the shift of genetic equilibrium toward increasing interpopopulation diversity (according to Wright's model). The calculation of the effective population size with the help of the Slatkin model turned out to be the lowest of the background mollusks in the study area (Ne = 0.39-0.83). However, the level of the effective population size calculated with the subdivision index (Fst and Gst) was equal to 6.2 and 7.3, respectively, which is comparable with other species of mollusks.
DNA methylation in early mice embryogenesis under the influence of bisphenol A
Authors: Noniashvili Ekaterina M. , Grudinina Natalia A. , Kustova Marija E. , Tran Van Truong , Suchkova Irina O. , Pavlinova Larisa I. , Sasina Ludmila K. , Dergacheva Natalia I. , Sofronov Henrikh A. , Patkin Eugene L.
Published: October 2017

Background. Nonsteroid estrogen bisphenol A (BPA) can have a detrimental effect on human health, and therefore poses a potential threat to humans. The critical window for the effect of BPA is the time of early development of the embryo, especially during the activation of the embryonic genome during development to the stage of blastocyst. Therefore, it is especially important to understand how DNA methylation is modified in embryos of the earliest developmental period under the influence of BPA. Materials and methods. Mice hybrids F1 (CBAXC57BL) were once administered 0, 8 mg of BPA per mouse and the level of DNA methylation was estimated by detection the fluorescence of antibodies against 5-MeC in nuclei of GD3 and GD9 embryos. In other series, the level of DNA methylation and the rate of blastocyst development were estimated following cultivation of one- and two cells embryos in the presence of BPA (50 or 100 M) during 72-96 hours in vitro. Results. BPA exposure induced the decrease of the level of DNA methylation in GD3embryos received toxicant in utero, the amount of blastomeres in these embryos was decreased too. The level of DNA methylation in GD9 embryos was slightly higher than in control group. Upon cultivation of one-two cells embryos, BPA decreased the level of DNA methylation and the rate of embryos development to blastocyst stage. Conclusion. We have determined that early embryogenesis is highly sensitive period to the BPA effects. Such effect is most likely due to active reprogramming processes in this period, primarily related to DNA demethylation/methylation de novo of both the whole genome and individual genes.
El logro de la convivencia pacífica: un reto en salud mental que convoca a la academia y la comunidad
Authors: Díaz U. Olga Stella , Sánchez C. Nohora
Published: October 2017

Editorial
Interrupción voluntaria del embarazo por violación: conocimientos, actitudes y prácticas de los profesionales de la salud en Caquetá
Authors: Ibarguen S. Marilyn
Published: October 2017

El objetivo de este estudio descriptivo transversal fue describir los conocimientos, actitudes y prácticas de profesionales de la salud que laboran en el departamento de Caquetá sobre la interrupción voluntaria del embarazo a causa de violación en un contexto de conflicto armado. Para ello, se realizó una encuesta a 117 profesionales de la salud (médicos y enfermeras) de diferentes instituciones prestadoras de salud del departamento. Tamaño muestral calculado: 116, margen de error del 5 % y nivel de confianza del 90 %. El 95 % de los profesionales conoce que en Colombia es legal la interrupción voluntaria del embarazo cuando este es producto de una violación; el 17 % manifestó que la denuncia es el único requisito para acceder a dicho procedimiento. El 50 % respondió que la aspiración manual endouterina es uno de los métodos utilizados y el 62 % consideró que la mujer embarazada a causa de violación debe hacer lo que considere correcto. El 47 % de los encuestados dijo no practicar la interrupción voluntaria del embarazo (IVE) pero sí remitir el caso. Se identificó que los profesionales tienen información relacionada con la atención a víctimas de violencia sexual. Aun así, hay algunas dificultades en el reconocimiento formal de los requisitos para prestar este servicio ya que, en zonas de conflicto armado, las pacientes refieren que su integridad física podría verse comprometida si interponen una denuncia por violencia sexual, por lo cual la interrupción del embarazo se puede realizar bajo la causal salud. Además, se logró evidenciar que los profesionales prefieren remitir los casos de IVE.
Legislación en enfermería: el sinuoso camino hacia la autonomía
Authors: Serdarevich Úrsula
Published: October 2017

La presente es una reflexión sobre el recorrido histórico de las leyes que regulan la enfermería como profesión, la diversificación de roles y las responsabilidades que pueden ser fuente de conflicto. También se ocupa de repensar las iniciativas destinadas a la captación del recurso humano enfermero. Para tal fin, se propone un análisis de la normativa profesional de enfermería en Argentina orientado a configurar competencias, alcances y grado de autonomía.

 

 
Germinação e crescimento inicial de variedades de feijão caupi submetidas a diferentes concentrações salinas
Authors: Coelho Daniela Siqueira , Silva José Aliçandro Bezerra da , Nascimento Russaika Lírio , Costa Josenara Daiane de Souza , Seabra Tales Xavier
Published: October 2017

A utilização de variedades tolerantes ao estresse salino tem sido essencial para o estabelecimento de culturas comerciais em áreas salinas. O objetivou-se avaliar a germinação e o crescimento inicial de plântulas de quatro variedades de feijão caupi submetidas a diferentes níveis de estresse salino. As sementes das cultivares BRS Tapaihum, BRS Pujante, BRS Acauã e BRS Marataoã foram semeadas em espumas, dispostas em bandejas e umedecidas com as seguintes concentrações de NaCl: 0, 50, 100, 150 e 200 mM. Foram determinadas as variáveis: percentual de germinação, índice de velocidade de emergência, tempo médio, frequência relativa de germinação, comprimento da parte aérea e teor de água das plântulas. As variedades de feijão caupi apresentaram perda na capacidade germinativa a partir da concentração de 50 mM de NaCl. Também foi verificado que a incidência da salinidade promoveu uma diminuição da velocidade com que as variedades realizaram seus eventos bioquímicos, fisiológicos, morfogênicos necessários ao processo de germinação e formação das novas plantas.

Germination and initial growth of cowpea cultivars under salinity stress

Abstract: The use of varieties tolerant to salinity stress conditions has been essential for the crops establishment in are asthat experience with this problem. The aim of this study was to evaluate the germination process and early growth of seedlings of four varieties of cowpea under different levels of salinity. The seeds of BRS Tapaihum, BRS Pujante, BRS Acauã and BRS Marataoã were sown in foam, arranged in tray sand watered with the following NaCl concentrations: 0,50, 100, 150 and 200mM. The analized variables were Percentage of Germination, Emergence Speed Index, mean time, Relative Germination frequency, shoot length and water content of seedling. The cowpea varieties showed loss of germination capacity from 50 mM NaCl concentration. It was also verified that the salinity incidence promoted a decrease of the speed with which the varieties realized their biochemical, physiological, morphogenic events necessary to the process of germination and formation of the new plants.