bluuebunny/crossref_metadata_2025 huggingface dataset:
Formación pedagógica y su vinculación disciplinar en docentes universitarios del área de salud. Una indagación en universidades de Argentina y Chile
Authors: Lucchese Marcela , Solis-Soto María Teresa , Pérez Carlos , Novella Lourdes , Hernández Cristina , Burrone María Soledad
Published: November 2022

Se presentan los resultados de un estudio con enfoque cualitativo, cuya intención fue indagar el sentido de la formación pedagógica e interpretar la vinculación entre la formación pedagógica y disciplinar en salud en dos universidades públicas. Se implementaron cuestionarios y entrevistas a docentes de carreras del área de salud en Argentina (n=18) y Chile (n=14). Se trabajó desde el método de las comparaciones constantes propuesto por Glaser y Strauss. Los resultados evidencian tres categorías de análisis: la formación pedagógica focalizada en diversos modos de referencia vinculados a la docencia; la formación pedagógica como una cuestión que se desplaza entre la intuición y la necesidad y la vinculación entre lo pedagógico y lo disciplinar. El estudio muestra la necesidad de potenciar la formación pedagógica y la vinculación entre lo pedagógico y disciplinar en el ejercicio de la docencia en educación superior en el área de salud.
El juego cooperativo e inclusivo en los recreos como impulsor del desarrollo de habilidades sociales en la infancia
Authors: Mairal-Llebot María , Liesa Orús Marta , Latorre Cosculluela Cecilia
Published: November 2022

La detección de actitudes y conductas de exclusión y rechazo durante el tiempo de recreo llevó al desarrollo del proyecto de los "Recreos Cooperativos e Inclusivos". A través del presente artículo, se pretende dar a conocer dicho proyecto además de aportar evidencias teóricas sobre cómo y por qué contribuye al desarrollo y aprendizaje de habilidades sociales de los niños y las niñas que participan en él. Las conclusiones a las que se arribaron demuestran que los "Recreos Cooperativos e Inclusivos" favorecen la competencia social de los niños y las niñas por los siguientes motivos: a) facilitar la incorporación de elementos inclusivos propios del juego; b) utilizar el juego como estimulación para la interacción entre pares; c) permitir que los niños y las niñas vivencien en primera persona el proceso de socialización y d) aprovechar el recreo como escenario por su vinculación al juego y la libertad de los infantes y de las infantas.
An incidental finding of cervical esophageal diverticulum misdiagnosed as thyroid tumor
Authors: Yingqian Zhou , yin guoping
Published: November 2022

We present the case of a 75-year-old female patient was misdiagnosed as
thyroid tumor, but was changed to cervical esophageal diverticulum by
cervical enhancement CT before the operation.
Efficacy of pharmacological management of orthostatic hypotension- a systematic review and meta-analysis
Authors: Kulkarni Spoorthy , Jenkins Danny , Pavey Holly , Phillips Veronica , Mir Fraz
Published: November 2022

Introduction Orthostatic hypotension (OH) is associated with
cardiovascular mortality and morbidity. Non-pharmacological and
pharmacological therapies are employed in the management of OH. The aim
of this systematic review and meta-analysis is to provide an up-to-date
review of the efficacy parameters of pharmacological therapies. Methods
Medline, Embase, Cochrane Library, and Scopus were searched
(inception-July 2021), and published articles with randomized control
trials, meeting inclusion and exclusion criteria were quality assessed
(Risk of Bias 2 tool). Assessment for trends in patient-related outcome
measures and postural blood pressure improvement was undertaken. Studies
reporting postural systolic blood pressure (SBP) before and after
intervention in comparison to placebo were included in a meta-analysis
using inverse -variance in a random-effects model. Results 19 articles
were included in the systematic review. The orthostatic symptoms
questionnaire (OHQ) was the most common patient-related outcome measure
utilized in trials. Six studies included in the meta-analysis
demonstrated that pharmacological therapies (pyridostigmine, midodrine,
atomoxetine, yohimbine) improved postural SBP compared to placebo, with
a mean rise of 12.50 mmHg [95% CI: 6.01, 18.98; p
value<0.001, I2 =97%]. Midodrine showed the highest impact
on SBP, with a mean SBP of 16.11 mmHg [95% CI: 5.59, 26.63; p=0.003,
I2 =99%]. Conclusions Pharmacological treatment can significantly
increase postural SBP, however with significant heterogeneity related to
trial designs. Further efforts to homogenize outcome measures,
incorporating symptom improvement and reduction in the postural drop and
testing for a prolonged duration of therapy would strengthen the
evidence, and improve the translatability of findings in clinical
settings.
Development of N-terminally modified variants of the CXCR4-antagonizing peptide EPI-X4 with increased plasma stability
Authors: Harms Mirja , Almeida-Hernández Yasser , Alfonso Armando Rodríguez , Habib Monica , Gilg Andrea , Albers Dan , Ahmed Nermin , Abadi Ashraf , Weidinger Gilbert , Ständker Ludger , Wiese Sebastian , Sanchez-Garcia Elsa , Münch Jan
Published: November 2022

EPI-X4 is a natural peptide antagonist of CXCR4, an established drug
target in inflammatory diseases and cancer. Advanced derivatives of
EPI-X4, such as EPI-X4 JM#21, have shown promising therapeutic effects
in animal models of CXCR4-associated diseases but suffer from poor
stability in blood. We here aimed to design and characterize EPI-X4
analogs that effectively antagonize CXCR4 while remaining stable in
human plasma. We found that EPI-X4 analogs are stable against
degradation by endopeptidases. However derivatives are are prone to
degradation by exopeptidases which target the peptides’ N- but not the
C-terminus. Modifications of the peptide N-terminus by introducing
D-amino acids or acetyl residues resulted in EPI-X4 derivatives with
greatly enhanced plasma stability. The identified lead candidates EPI-X4
JM#29, JM#173, and JM#174, which contain D-amino acids L or I at
position 1, were as active in binding and antagonizing CXCR4 as EPI-X4
JM#21, and remained active even after 8 hours of incubation in plasma.
Molecular dynamics simulations showed that the binding mode of these
stabilized EPI-X4 derivatives to CXCR4 is similar to the binding of
JM#21. The peptides establish conserved interactions with acidic
residues in the minor subpocket and the extracellular loops 1 and 2 of
the receptor. None of the novel EPI-X4 leads showed any signs of
toxicity in zebrafish embryos, paving the way for further evaluation of
the pharmacokinetic and therapeutic properties of this new generation of
EPI-X4 analogs in rodent models.
An Adaptive Distance Protection Scheme for Transmission Lines Connected to DFIG Wind Farms Based on Setting Groups Procedure
Authors: fattahyan Yousef , Ramezani Nabiollah , Ahmadi Iraj
Published: November 2022

Generally, wind speed alters continuously during a day and lead to
fluctuating output power of a wind farm. Connecting such a wind farm to
the transmission line of grid causes a malfunction in the performance of
the backup zone of the distance relays due to the random nature of
generation and the number of connected wind turbines (wind farm
penetration). In this study, a new adaptive setting groups-based method
has been proposed to set the second zone of the distance relay in the
grid with a wind farm equipped with a doubly fed induction generator
(DFIG). In this method, we also taken into account the uncertainty of
wind fluctuations and the availability of wind turbines. A Markov model
is developed to implement these features. To determine the impedance
setting of each of the set groups of the second zone in the distance
relays of the remote bus, the obtained impedances are clustered in four
clusters by using the combination of K-means and particle swarm
optimization (PSO) algorithms. Finally, details of the analysis results
of this issue have been compared with other methods available in the
literature. The validity and accuracy of the proposed approach also have
been assayed and confirmed.
Upregulation of proBDNF/p75NTR signaling in lymphocytes and its correlation with inflammatory markers in patients with major depression
Authors: Yang Chun-Rui , Liang Rui , Meng Fanjie , zhou fiona , Zhang Xiaoyang , Ning Li , Liu Yuan , Wang Zhiqiang , Liu Shuang , Zhou Xin-Fu
Published: November 2022

Major depressive disorder (MDD) is a serious mental disorder with
unclear pathogenesis. ProBDNF is the precursor protein of brain derived
neurotrophic factor (BDNF) expressed in the central nervous system and
peripheral tissues. Previous studies showed that the blood levels of
both proBDNF and inflammatory cytokines in MDD were increased, but which
blood cell types express proBDNF and its receptors is not known.
Furthermore, the relationship between proBDNF/p75NTR and inflammatory
cytokines in peripheral blood of MDD is unclear. Peripheral blood
mononuclear cells (PBMCs) and serum were obtained from depressive
patients (n=32) and normal donors (n=20). Using flow cytometry analysis,
we examined which blood cells express proBDNF and its receptors. Q-PCR
and Western blots showed proBDNF, p75NTR and sortilin levels were
significantly increased in PBMCs from MDD patients compared with that
from the normal donors. Flow cytometry studies showed that proBDNF and
p75NTR were present mainly in CD4+ and CD8+ T-cells and CD19+ B cells.
The number of proBDNF and p75NTR positive CD4+, CD8+ T cells and CD19+ B
cells from MDD patients was increased and subsequently reversed after
therapeutic management. Inflammatory cytokines in PBMC from MDD patients
were also increased. The levels of IL-1β and IL-10 were also positively
correlated with the major depression scores, while the levels of TNF-α
and IL-6 were negatively correlated with the major depression scores.
Intriguingly, the levels of sortilin was positively correlated with
IL-1β. Our data also suggest that proBDNF/p75NTR/sortilin signaling
pathway in T and B cells may serve as biomarkers for MDD.
Geriatrics 8 scores as a predictor of postoperative outcome in elderly patients with Head and Neck cancer in Rajavithi Supertertiary Care Hospital .
Authors: Chindavijak somjin
Published: November 2022

Background : To determine preoperative Geriatric 8 (G8) score in
predicting postoperative complications for elderly head and neck cancer
patients . Material and Methods: The prospective study in elderly head
and neck cancer patients who underwent surgery during December 2020-
June 2022 . G8 score were collected before surgery and analysed for the
association with complication outcome. Result : Of 104 patients included
in this study ,The mean age was 68.84±6.99 years .The Geriatric 8
(G8)score < 14 which were frail group in 73 cases (70.2%) The
Clavien-Dindo complications grade III-IV were 30 patients (28.8%).
Among these groups ,26 patients (86.7%) was in frail groups and 4
patients (13.3%) with non frail group which is statistically
significant different (p=0.019) and Odd ratio of 3.32 , CI =1.01-10.87,
p=0.048 Conclusion : The G8 score is a practical tool for prediction
post operative complication in elderly Head and Neck Cancer surgery .
Keyword : Geriatric 8 score , Geriatric Head and neck cancer , post
operative complication
Improve crop root architecture by resolving self-intersections of individual roots
Authors: Pietrzyk Peter , Bucksch Alexander
Published: November 2022

Branching patterns in plant roots are associated with complex traits
such as stress-tolerance, yield, and the ability for carbon
sequestration. The capability of the root system to branch allows the
plant to search the soil for water and nutrients. For example, a
reduction of higher order roots may determine how well a crop plant
tolerates drought, whereas the ability to develop more higher order
roots determines how well a crop plant tolerates a nutrient deficient
soil. Measurements of traits such as rooting depth, root width or
specific root length, however, often fail to capture the complex
morphological arrangement of the root system. Therefore, a more rigorous
analysis of root branching patterns is highly relevant as they are
linked to the ability of plants to respond to abiotic stresses, such as
drought and nutrient deficiency. Despite the need, it remains a
challenge to extract information about branching patterns due to
intersecting and overlapping roots in 2D and 3D imaging data. Such
occlusion problems add ambiguity and outliers to root trait
measurements. We present an algorithm to resolve such intersections in a
globally optimal way based on simple heuristics such as straightness of
roots - thus being dimension independent. This will enable quantitative
analysis of how root branching patterns change in response to abiotic
stress using shape descriptors. The possibility to computationally
measure very dense branching structures with thousands of intersections
will support the breeding of plants that withstand increasing areas of
drought and nutrient deficiencies in the world.
Digital quantification and characterization of root architectural diversity across collard landrace varieties
Authors: Brazelton Antonio , Topp Christopher
Published: November 2022

Urban agriculture has been broadly acknowledged for its potential to
reduce carbon emissions, increase food security, and improve economic
growth in some of the most vulnerable communities in the United States.
Collard (B.oleracea var. viridis) is a diploid leafy
green, grown on urban farms and community gardens across the country,
including the St. Louis Metro region. Beyond their nutritional
importance, collards provide urban and commercial agronomic systems with
a plethora of important ecosystem services. They scavenge nitrogen and
available resources, suppress weeds, and act as a biofumigant to control
soil-borne pests and pathogens. Recently, The Heirloom Collard Project
characterized the above-ground growth habits of 18 landrace collard
varieties across 250 organic gardens and farms. Little work has been
published to investigate collard root system architecture, which
influences both quality traits and ecosystem services that contribute to
sustainable crop production. The objectives of this research are to 1)
quantify root spatial and temporal diversity across 18 landrace collard
varieties, and 2) evaluate the relationship between root phenotype and
urban farmer crowd-sourced data for key traits such as germination rate,
disease resistance, vigor, yield, flavor, and winter hardiness. This
work will lead to the development of a participatory framework for urban
farmers and chefs to select varieties with improved root architecture
based on regional needs.
NAPPN Annual Conference Abstract: Deep Interactive Annotation with Prototype Learning
Authors: Guo Xiaolei , Zare Alina
Published: November 2022

Interactive Annotation for object delineation can be considered as a semi-supervised few-shot learning problem where machine learning models learn from a small set of annotated pixels and generalize to the entire picture to extract the object of interest. One aim of interactive annotation is to reduce the effort of manually labeling data. Some existing works attempted to address this problem with deep metric learning so that the encoding layers in the network are able to extract features that boost discriminability among pixels belonging to different classes. To keep the data structure in the embedding space, metric loss with prototypes has been proposed. In our work, we improved the existing methods by developing a new objective function to update the network and prototypes simultaneously. The prototypes are optimized based on the loss that enhances their dissimilarity instead of clustering or sampling from the dataset. Moreover, we designed a GUI with the proposed method for interdisciplinary collaboration of image-support plant phenotyping studies.
Application of Transfer Learning for Root Segmentation in Assessment of Plant Health
Authors: Rossiter Justin , Zare Alina , Palmer Todd M , Pringle Elizabeth G , Milligan Patrick
Published: November 2022

Minirhizotron imagery can be used to assess plant root health, and the
amount of data for analysis motivates automation of root detection
through use of neural networks. Building upon previous work, we show
that we can use transfer learning from our PRMI dataset to assess root
health across twelve classes of a new dataset to answer questions
regarding how root health is affected by access of a tree by large
herbivores, site infestation by Pheidole megacephala, and location of
the tree. This dataset was collected from three paired sites at the Ol
Pejeta Conservancy in Laikipia, Kenya, and consists of 20,000 images
collected between September 2021 and May 2022. Each paired site
represents four locations based on all four possible combinations of
site infestation by Pheidole megacephala for at least 20 years and
existence of herbivore-exclusion fence to keep large herbivores out.
1,332 images across all twelve classes of site and treatment combination
were labeled with respective ground truths for model training. Our work
uses the UNet architecture using pretrained weights on the network
encoder and decoder which were obtained in 2019 in work which achieved
over 99% accuracy on a dataset of peanut and switchgrass imagery. In
our work, we found that training the model with our new dataset resulted
in consistent performance across all classes of our new dataset, with
over 99% accuracy for each class.
Perioperative bevacizumab in the treatment of colorectal cancer in patients with liver metastases
Authors: Nikolic Ivan , Manojlovic Nebojsa , Andric Zoran , Radosavljevic Davorin , Ristic Marija , Kovcin Vladimir
Published: November 2022

Introduction. Patients with colorectal cancer with metastases in the liver
parenchyma may benefit from perioperative chemotherapy with biological
agents and operative liver resection. Material and Methods. This
prospective, multicenter, non-interventional study included 191 previously
untreated patients with metastatic colorectal cancer and potentially
resectable or initially unresectable liver metastases who received
bevacizumab plus chemotherapy. The safety profile, as well as
progression-free-survival, response rate and conversion rate of initially
unresectable metastases to resectable were assessed. Results. A total of 40
adverse events were reported in 29/191 patients (15.2%), of which 31 were
serious adverse events. Among the serious adverse events, 14 were related to
the use of bevacizumab therapy, of which 4 were fatal due to serious adverse
events, but only one could be related to bevacizumab therapy. The median
progression-free period was 9 months (1 - 28). A high rate of response to
the applied therapy, 34.5% and 49%, was recorded in both groups of patients:
with initially unresectable and potentially resectable metastases in the
liver parenchyma. A significant part of patients with metastatic colorectal
cancer and metastases only in the liver parenchyma had a clinical benefit
from intensive chemotherapy with bevacizumab (disease control rate of 70%).
Conclusion. This study confirmed a favourable safety profile and
tolerability in terms of the incidence and severity of adverse and serious
adverse events. High rates of resectability in both groups of patients,
initially unresectable and potentially resectable, reflect the heterogeneity
of criteria in decision making about liver resection and emphasize the need
for establishing multisciplinary oncology teams and following the generally
accepted criteria.
No Association Between First Exposure to General Anaesthesia and Atopic Dermatitis in the Paediatric Population
Authors: Kim Dong Chan , Choi Young Woong , Lee Eun-So , Choi Jee Woong
Published: November 2022

General anaesthesia could affect various immune responses, including Th1 and Th2 immunity, which might also affect cells that play an important role in the pathogenesis of atopic dermatitis. However, the relationship between general anaesthesia exposure and atopic dermatitis remains unknown. The aim of this study was to investigate the risk of developing atopic dermatitis after first exposure to general anaesthesia in the paediatric population (18 years or under). A retrospective cohort study, including those exposed (n = 7,681) and unexposed (n = 38,405; control participants) to general anaesthesia (1:5 ratio), was conducted using national sample cohort data from 2002 to 2015. All participants were followed up for 2 years after cohort entry. The 2-year cumulative incidences of atopic dermatitis in the exposed and unexposed groups were 2.3% and 2.2%, respectively. In the subgroup analysis by age, the cumulative incidence was not significantly different between these cohorts. The risks of atopic dermatitis were not significant in the exposed group in the univariate model (hazard ratio 1.05; confidence interval 0.88–1.24) and in the multivariate model, wherein all covariates were adjusted (adjusted hazard ratio, 1.03; 95% confidence interval 0.87–1.23). The results suggest that children’s exposure to general anaesthesia was not associated with increased or decreased risk of atopic dermatitis.
Topical Metronidazole Versus Ivermectin for Low-density Demodex Rosacea: A Rater-blinded, Randomized, Split-face Trial
Authors: Yeh Marvin Chia-Han , Tsai Jerry , Huang Yu Chen , Wang Hsiao-Han
Published: November 2022

Abstract is missing (Short communication)
Exploring the factors that affect the acceptance and use of Electronic Health Records amongst secondary care staff in Kuwait: A mixed- methods study
Authors:   , Albazzaz Naser
Published: November 2022

Background: Despite investments into healthcare reform and health information technology (HIT), Kuwait has not fully utilised Electronic Health Records (EHR) in the public secondary care sector. As a result, adoption and maturity levels vary. Aims: The present study aimed (1) to evaluate the acceptance of EHR in public sec-ondary care hospitals in Kuwait, (2) to explore experiences and perceptions of EHR, (3) to understand barriers to the EHR, (4) to devise potential strategies to enhance user acceptance.Methods: In order to address the aims, the research has adopted a mixed-methods design utilising quantitative and qualitative methods. The quantitative study was conducted as an online survey of 399 Healthcare professionals in six public hospitals in Kuwait. It used the Technology Acceptance Model 2 (TAM 2) questionnaire to collect data. The qualitative study consisted of two phases. Phase one data were collected through semi-structured interviews with thirty healthcare professionals in three public hospitals. Phase two consisted of three semi-structured interviews with health care leadership in non-government secondary care sites that had already im-plemented EHR successfully.Results and findings: The TAM 2 survey found overall negative user attitudes. Per-ceived Ease of Use and Perceived Usefulness both predicted Intention to Use. How-ever, user perceptions demonstrated that HCPs trusted in EHRs to improve quality of care, reduce clinical errors and save time. Furthermore, HCPs experienced a lack of interoperability, information technology (IT) infrastructure, resources, and a lack of organisational cohesion and teamwork as barriers to EHR adoption and use. In addi-tion to that, interviewees expressed concerns about the safety and privacy of patient data. Conclusion: The evidence underscores the importance of strategic managerial investment into EHR adoption and use in Kuwaiti secondary care public hospitals. The study identified a need for better IT infrastructure, more appropriate staff training and monitoring of EHR implementation and use as strategies to enhance user acceptance.
Generalisations of Tropical Geometry over Hyperfields
Authors:   , Maxwell James
Published: November 2022

Hyperfields are structures that generalise the notion of a field by way of allowing the addition operation to be multivalued. The aim of this thesis is to examine generalisations of classical theory from algebraic geometry and its combinatorial shadow, tropical geometry. We present a thorough description of the hyperfield landscape, where the key concepts are introduced. Kapranov’s theorem is a cornerstone result from tropical geometry, relating the tropicalisation function and solutions sets of polynomials. We generalise Kapranov’s Theorem for a class of relatively algebraically closed hyperfield homomorphisms. Tropical ideals are reviewed and we propose the property of matroidal equivalence as a method of associating the geometric objects defined by tropical ideals. The definitions of conic and convex sets are appropriately adjusted allowing for convex geometry over ordered hyperfields to be studied.
Infection Prevention and Control for the Emergency Medical Services and 911 Workforce
Authors: Jenkins J. Lee , Hsu Edbert B. , Russell Anna , Zhang Allen , Wilson Lisa M. , Bass Eric B.
Published: November 2022

Objectives. To summarize current evidence on exposures to infectious pathogens in the emergency medical services (EMS) and 911 workforce, and on practices for preventing, recognizing, and controlling occupationally acquired infectious diseases and related exposures in that workforce. Review methods. We obtained advice on how to answer four Guiding Questions by recruiting a panel of external experts on EMS clinicians, State-level EMS leadership, and programs relevant to EMS personnel, and by engaging representatives of professional societies in infectious diseases and emergency medicine. We searched PubMed®, Embase®, CINAHL®, and SCOPUS from January 2006 to March 2022 for relevant studies. We also searched for reports from State and Federal Government agencies or nongovernmental organizations interested in infection prevention and control in the EMS and 911 workforce. Results. Twenty-five observational studies reported on the epidemiology of infections in the EMS and 911 workforce. They did not report demographic differences except for a higher risk of hepatitis C in older workers and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in minorities. EMS clinicians certified/licensed in Advanced Life Support have a high risk for blood and fluid exposure, and EMS clinicians had a higher risk of hospitalization or death from SARS-CoV-2 than firefighters whose roles were not primarily related to medical care. Eleven observational studies reported on infection prevention and control practices (IPC), providing some evidence that hand hygiene, standard precautions, mandatory vaccine policies, and on-site vaccine clinics are effective. Research on IPC in EMS and 911 workers has increased significantly since the SARS-CoV-2 pandemic. Conclusions. Moderate evidence exists on the epidemiology of infections and effectiveness of IPC practices in EMS and 911 workers, including hand hygiene, standard precautions, mandatory vaccine policies, and vaccine clinics. Most evidence is observational, with widely varying methods, outcomes, and reporting. More research is needed on personal protective equipment effectiveness and vaccine acceptance, and better guidance is needed for research methods in the EMS and 911 worker setting.
The Development of Qawā’idul I’lāl Teaching Materials by an Inductive Approach
Authors: Isnainiyah Isnainiyah , Al Farisi Mohamad Zaka , Sopian Asep
Published: November 2022

The teaching and learning process of I'lāl (vocal deviation) in Islamic boarding schools generally uses the book of Qawā'idul I'lāl. However, the book of Qawā'idul I'lāl is still very simple and has several shortcomings as follows: (1) it only contains simple i'lāl rules, (2) there is no explanation of the rules, (3) there are only a few examples, and (4) there is no material for practice. Therefore, the researcher intends to develop Qawā'idul I'lāl teaching materials with an inductive approach accompanied by practice questions. On another note, this research aims to describe the product's feasibility and legibility. This study uses a research and development (RD) design with a stage model developed by Borg Gall. The study results indicate that, in the aspect of feasibility, this development product is declared feasible after it is tested by experts on the material and media’s morphology and visual communication design, with a result of 82.6%. Regarding readability, the product development is categorized as independent after conducting the gap test with 86.1% and the Fog Index formula with a value of 2.543. Therefore, the results of developing the Qawā'idul I'lāl book with an inductive approach have implications for the ideal product of teaching materials for I'lāl learning (vocal deviation), especially in the pesantren environment.
A study on the impact of environmental and organizational factors on the effectiveness of platform-based transformation -Qualitative comparative analysis based on fsQCA
Authors:   North China University of Technology, School of Economics and Management, PR China, Xinhui Chen , Yaping Li ,   North China University of Technology, School of Economics and Management, Beijing, PR China
Published: November 2022

Driven by the new generation of digital intelligence technology, the platform economy has emerged as an important force to drive industrial development and enterprise growth, and how to improve the effectiveness of enterprise platform-based transformation has become an important issue. This paper uses a sample of 30 domestic listed enterprises and adopts the fuzzy set qualitative comparative analysis (fsQCA) method to select six representative factors from two dimensions, namely environment, and organization, to explore the effect of the grouping effect on the effectiveness of platform transformation of enterprises. The study found that there are three ways to help companies achieve high platform transformation effectiveness, namely digital level + managerial cognitive ability, digital level + resource allocation ability, and government support + resource allocation ability, as well as three paths that lead to low platform transformation performance. The findings suggest that companies can, on the one hand, strive to improve certain key elements and move towards similar paths according to their circumstances, or, on the other hand, make organizational changes to shift to favorable paths and avoid unfavorable ones. This study not only extends the theoretical research on the impact paths of platform-based transformation but also provides valuable references on how companies can develop platform-based transformation strategies.
Frequent association of vitiligo with autoimmune endocrine diseases: primary data of the Russian cohort of adult patients
Authors: Nuralieva NF , Yukina MYu , Troshina EA , Zhukova OV , Petrov VA , Volnukhin VA
Published: November 2022

There is evidence in the literature about more frequent association of vitiligo with autoimmune endocrine diseases (AEDs) compared to general population. No full-fledged studies aimed at assessing the prevalence of AEDs in the Russian cohort of adult vitiligo patients have been conducted. The study was aimed to assess the prevalence of AEDs in the cohort of Russian adult vitiligo patients. Patients with vitiligo monitored in two clinics, the Endocrinology Research Centre (Clinic 1; n = 39) and the Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology (Clinic 2; n = 26), were enrolled. Along with clinical examination, screening laboratory tests were performed in all patients in order to reveal AEDs. The majority of patients (more than 95% of cases) had nonsegmental vitiligo. Among patients monitored in Clinic 1, AEDs were diagnosed in 85% of cases: isolated AEDs accounted for 39%, while multiple AEDs were found in 46% of cases. Autoimmune thyroid diseases were diagnosed in 69% of cases. Autoimmune adrenal insufficiency was found in 28% of patients, type 1 diabetes mellitus in 21%, hypoparathyroidism in 13%, hypergonadotropic hypogonadism in 10%, endocrine ophthalmopathy in 10% of patients. Among patients monitored in Clinic 2, AEDs were diagnosed in four patients (15% of cases): three patients had primary hypothyroidism in the outcome of autoimmune thyroiditis, one patient had Graves' disease. Thus, the prevalence of AEDs in patients with vitiligo may vary between 15–85%. Vitiligo is most often associated with autoimmune thyroid diseases (15–69%). Vitiligo patients should undergo annual screening aimed at detection of autoimmune endocrine disorders, especially thyroid diseases.
Osobennosti genotipicheskoj rezistentnosti k ftorhinolonam u Mycobacterium tuberculosis, cirkuliruyushchih v Rossijskoj Federacii
Authors: Андреевская С. Н. , Смирнова Т. Г. , Черноусова Л. Н. , Ларионова Е. Е. , Киселева Е. А. , Эргешов А.
Published: November 2022

Ftorhinolony — osnovnaya gruppa preparatov, primenyaemyh dlya lecheniya tuberkuleza s mnozhestvennoj lekarstvennoj ustojchivost'yu (MLU-TB). Cel'yu issledovaniya bylo ocenit' raznoobrazie mutacij v gene gyrA, a takzhe ustanovit' associaciyu mutacij v gyrA s fenotipicheskoj ustojchivost'yu k levofloksacinu i obshchim profilem lekarstvennoj ustojchivosti vozbuditelya. Issledovanie provedeno na diagnosticheskom materiale ot 2836 bol'nyh tuberkulezom legkih. Dlya opredeleniya mutacij v gyrA ispol'zovali nabory «TB-BIOCHIP-2» ili «Amplitub-FQ-RV». Fenotipicheskuyu lekarstvennuyu chuvstvitel'nost' M. tuberculosis (MBT) opredelyali v sisteme BACTEC MGIT 960. Pokazano, chto u MBT dominirovali mutacii D94G (41,63%; 95%DI: 38,03–45,32%) i A90V (21,32%; 95%DI: 18,44–24,50%), prichem izolyaty s etimi mutaciyami byli polucheny v tom chisle i ot vpervye vyyavlennyh bol'nyh tuberkulezom legkih. Ustanovleno, chto mutaciya D94A ne yavlyalas' strogo associirovannoj s fenotipicheskoj ustojchivost'yu k ftorhinolonam. Ustojchivost' k ftorhinolonam, kak pravilo, byla associirovana s mnozhestvennoj lekarstvennoj ustojchivost'yu (93,52%; 95%DI 91,43–95,12%). V 2,31% (95%DI 1,78–3,00%) sluchaev vyyavlena genotipicheskaya geterorezistentnost' k ftorhinolonam: smeshannye populyacii vklyuchali 2—4 pula MBT s raznoj strukturoj QRDR gyrA. Na osnovanii poluchennyh rezul'tatov mozhno zaklyuchit', chto v sovremennoj populyacii MBT proiskhodit formirovanie ustojchivosti k ftorhinolonam, kak pravilo, na fone uzhe imeyushchejsya MLU. Naibolee perspektivnymi v evolyucionnom plane predstavlyayutsya MBT s mutaciyami v gyrA D94G i A90V.
KONTRIBUSI PENDIDIKAN AGAMA ISLAM TERHADAP SELF CONTROL DAN KECERDASAN EMOSIONAL PESERTA DIDIK DI SMK KARTIKATAMA METRO
Authors: Astuti Kuntari Puji , Sarbini Sarbini , Iswati Iswati
Published: November 2022

Pendidikan agama Islam merupakan mata pelajaran yang penting dalam pembentukan self control dan kecerdasan emosioanal peserta. Tujuan penelitian mengetahui proses pembelajaran Pendidikan Agama Islam,mengetahui kondisi self control dan kecerdasan emosional peserta didik, mengetahui kontribusi pendidikan agama Islam terhadap self control dan kecerdasan emosional peserta didik, mengetahui faktor-faktor pendukung dan penghambat self control dan kecerdasan emosional peserta didik. Jenis penelitian yang digunakan merupakan penelitian kualitatif, tehnik pengumpulan data wawancara, observasi, dan dokumentasi dituangkan dalam analisis deskriptif berbentuk kalimat dalam bentuk paragraf. Penelitian tentang kontribusi pendidikan agama Islam, membentuk self control dan kecerdasan emosional yang efektif. Hasil penelitian menunjukan pembelajaran di SMK Kartikatama cukup baik dan kondusif peserta didik juga merespon, kondisi self control dan kecerdasan emosional bermacam-macam yaitu baik dan belum baik, pembentukan self control dan kecerdasan emosional peserta didik tidak terlepas dari indikator yaitu pembiasaan, kesadaran dan kendali diri. Penelitian ini dapat disimpulkan bahwa Kondisi self control dan kecerdasan emosional peserta didik di SMK Kartikatama 2 Metro ada dua macam yaitu Pertama, baik, Kedua, peserta didik yang sulit dibimbing. Kontribusi pendidikan agama Islam terhadap self control dan kecerdasan emosional peserta didik di SMK Kartikatama berperan penting yaitu mengenali kepribadian peserta didik, menanamkan kesadaran diri, membentuk pengendalian diri peserta didik.
STUDI KOMPARASI PESERTA DIDIK PROGRAM TAHFIDZ QUR`AN DAN REGULER DALAM HASIL BELAJAR AL-QUR`AN HADITS DI MTs PSA ISTIQOMAH ISLAMIYYAH TULANG BAWANG BARAT
Authors: Aini Naharin , Kuliyatun Kuliyatun , Iswati Iswati
Published: November 2022

Hasil belajar Al-Qur`an Hadits peserta didik dipengaruhi oleh faktor internal dan faktor eksternal. Tujuan penelitian ini untuk mengetahui hasil pembelajaran Al-Qur`an Hadits di MTs PSA Istiqomah Islamiyyah antara peserta didik program Program Tahfidz Qur`an Dan Reguler dan untuk mengetahui perbedaan hasil belajar Al-Qur`an Hadits antara peserta didik program Program Tahfidz Qur`an Dan Reguler. Jenis penelitian merupakan jenis penelitian kuantitatif dengan teknik pengumpulan data menggunakan angket, dokumentasi, interview dan observasi, dengan jumlah populasi 26 peserta didik yang terbagi dari 13 peserta didik program Tahfidz Qur`an dan 13 peserta didik program Reguler. Hasil Belajar Peserta Didik Program Tahfidz dapat disimpulkan bahwa nilai hasil belajar Al-Qur`an Hadits tergolong cukup. Sementara hasil belajar peserta didik program Reguler dapat disimpulkan bahwa nilai hasil belajar Al-Qur`an Hadits tergolong baik. Pengujian hipotesis pada penelitian ini menggunakan analisis uji T tes dengan hasil penelitian bahwa t hitung = 67,61 lebih besar dari t yang berada pada tabel baik pada taraf signifikansi 5% = 2,063 maupun 1% = 2,796. Dengan demikian pengujian hipotesis menunjukan bahwa ada prestasi belajar antara peserta didik Reguler dan Tahfidz Pada Mata Pelajaran Al-Qur`an Hadits.
PENINGKATAN HASIL BELAJAR SISWA MENGGUNAKAN MODEL TEAMS GAMES TOURNAMENS PADA SISWA DALAM MATA PELAJARAN AQIDAH AKHLAK KELAS VIII MTS MUHAMMADIYAH 1 WAY BUNGUR TAHUN PELAJARAN 2019/2020
Authors: Ismail Maulana , Iswati Iswati , Kuliyatun Kuliyatun
Published: November 2022

Pembelajaran merupakan perpaduan yang harmonis antara kegiatan pengajaran yang dilakukan guru dan kegiatan belajar yang dilakukan oleh siswa. Dalam kegiatan pembelajaran tersebut, terjadi interaksi antara siswa dengan siswa, interaksi antara guru dan siswa, maupun interaksi antara siswa dengan sumber belajar. Diharapkan dengan adanya interaksi tersebut, siswa dapat membangun pengetahuan secara aktif, pembelajaran berlangsung secara interaktif, inspiratif, menyenangkan, menantang, serta dapat memotivasi peserta didik sehingga mencapai kompetensi yang diharapkan. Tujuan penelitian adalah untuk meningkatkan hasil belajar PAI menggunakan model pembelajaran Teams Games Tournamen dalam mata pelajaran aqidah akhlak.Jenis penelitiaan ini adalah penelitian tindakan kelas (classroom action research). Teknik analisis data yang digunakan adalah analisis statistic deskriptif. Berdasarkan hasil analisis statistic deskriptif diperoleh rata-rata motivasi belajar peserta kelas VIII pada mata pelajaran akidah akhlaak pretest yaitu 68% dan rata-rata motivasi belajar peserta didik kelas VIII pada mata pelajaran aqidah akhlak posttest yaitu 75%. Sehingga di dalam penelitian ini dapat disimpulkan bahwa penerapan model pembelajaran Teams Games Tournament meningkatkan motivasi belajar peserta didik kelas VIII di sekolah MTs Muhammadiyah 1 Way Bungur.
The Transformation of Romanian Internal Public Audit between 2006 and 2020
Authors:   ", MOLDOVAN Octavian ,   Postdoctoral researcher, School of Public Administration and Public Policies, Lecturer, Department of Public Administration and Management, Faculty of Political, Administrative and Communication Sciences, Babeş-Bolyai University, Cluj-Napoca, Romania", MACARIE Felicia Cornelia ,   "Professor, Department of Public Administration and Management, Faculty of Political, Administrative and Communication Sciences, Babeş-Bolyai University, Cluj-Napoca, Romania"
Published: November 2022

"The article analyzes how internal public audit (IPA) transformed in Romania between 2006 and 2020, in order to explore: (a) the degree in which cen tral and local public institutions organized their IPA activities as a specialized department or in an asso ciative structure; (b) how did the human resources allocated to IPA activities transformed in this period (focusing on employment, the ability to cover the needs of public organizations and the educational/ professional specialization of internal auditors), and (c) how IPA missions changed over time. The empiri cal research consists of a detailed analysis of official annual reports published by the Central Harmoniza tion Unit for Internal Public Audit, thus ensuring the reliability of the analysis. Our main results indicate the existence of multiple differences between central and local public organi zations, regarding their degree/level of IPA activities organization (especially before 2013) and the num ber of organizations each internal public auditor was tasked to audit (ranging from 1 at the central level to almost 8 at the local level). Unfortunately, the under staffing of IPA departments/ bureaus is not condu cive to an accurate identification and assessment of potential organizational weaknesses and risks, thus potentially hindering the performance of both central and local public institutions. "
Discussing the Spatial Underpinnings of Tourism Policy and Planning in Romania
Authors:   ", POPESCU Claudia ,   Professor, Department of Tourism and Geography, Faculty of Business and Tourism, Bucharest University of Economic Studies, Bucharest, Romania Institute of Geography, Romanian Academy, Bucharest, Romania", PERSU Mihaela ,   "Senior Researcher, Ph.D., Institute of Geography, Romanian Academy, Bucharest, Romania"
Published: November 2022

"The paper examines the spatial concepts and mechanisms that drive the reconfiguration of the tourism space and provide policy-relevant informa tion. Mapping the spatial patterns of tourism supply and demand at finely-grained data over the last two decades, the analysis employs spatiotemporal and scaling methods to capture the interactions and de pendencies among tourism concentrations. The findings point to space-tourism realignments based on heterogeneous concentration patterns and trajectories of change, supply growth and ex pansion at the first level of contiguity, and diffused domestic vs. polarized international arrivals. The bi nary approach of tourism concentrations of supply and demand with varying location quotients enables the identification of both differences and similarities in terms of contextual and tourism development in dicators. In support of context-sensitive policy inter ventions, we argue that space should be regarded as a central dimension of the tourism development pol icy. Providing a snapshot of the tourism concentra tions in 2019, the study may count as a baseline ref erence for further analyses in post-pandemic times."
Impact of Leadership and Gender on Civil Servants’ Resilience in the Romanian State’s Public Administration
Authors:   Professor, Ph.D., Department of Administration and Public Management, Bucharest University of Economic Studies, Bucharest, Romania, PROFIROIU Alina G. , NASTACĂ Corina C. ,   Teaching assistant, Ph.D., Department of Administration and Public Management, Bucharest University of Economic Studies, Bucharest, Romania
Published: November 2022

"The research analyses the leadership styles prac ticed in the Romanian public administration, the gender differences regarding the practiced leader ship and in terms of exhibiting behaviors that could lead to the development of civil servants’ resilience, trying to investigate the relation between leadership, gender, and resilience. The paper contributes to the scientific literature in the field by analyzing three concepts that are not usually explored together and especially in the public administration. The research methodology consists of a sociological survey con ducted in the Romanian public administration where 766 civil servants agreed to participate. The research revealed that the studied leaders present a mix of characteristics where transforma tional and transactional behaviors are predominant. Regarding gender differences, both men and wom en are considered to lead in a similar manner, but a higher preference for male leaders was observed. Men’s leadership behaviors are better appreciated, indicating the presence of gender stereotypes and a certain level of prejudice against women. The studied leaders possess the necessary character istics for developing civil servants’ resilience, being perceived as exhibiting supportive, encouraging, and motivating attitudes when their subordinates faced difficult moments in their careers. Also, the exis tence of a direct relation between transformational leadership and resilience was observed."
Ontology and Ecological Aesthetics in Jeanette Winterson’sArt & Lies
Authors: Melhem Qateralnada
Published: November 2022

This essay seeks to trace and investigate ecologically inflected concepts in Jeanette Winterson’sArt & Lies. The general tendency in ecological and ecocritical analyses has long been a selective focus on how nature is represented in literary texts; however, the ecological crisis, globalization, and technological factors that drive environmental degradation are all tethered at the root to preliminary concepts relating to human behaviours, beliefs, values, and expectations. This essay maintains that the diagnoses should begin at the level of culture since it is at that level that ecological problems begin to germinate. Through a discussion that draws on Federico Campagna’sTechnic and Magic: The Reconstruction of Reality, this essay performs a thematic reading ofArt & Lies. Using Campagna’s elucidation of the metaphysical assumptions that inform environmentally destructive practices, it argues thatArt & Liesdraws attention to these assumptions and identifies in them an obstacle to raising ecological awareness. Additionally, by employing an approach that draws on ecocritical scholarship, this essay discusses how formal and linguistic experimentation inArt & Liesinscribes ecological viewpoints and attempts the mission of redress that could benefit a more ecologically attuned future.
Nighttime Invasions, Colonial Dispossession, and Indigenous Resilience in Richard Wagamese’sIndian Horse
Authors: Wiese Doro
Published: November 2022

This essay demonstrates how Richard Wagamese employs oral storytelling techniques to make the complex idea of Indigenous dispossession sensually and intellectually accessible to readers of his novel,Indian Horse. The Wabseemoong First Nation writer depicts the devastating effects of white entitlement when rendering character Saul Indian Horse’s experiences in Canada’s residential schools and the effect those schools had on his subsequent life. Using narrative analysis, it will be shown how Saul loses his ability to perceive places as being alive and resonant, and is thereby dispossessed on an individual, social, and spiritual level. Furthermore, Wagamese’s descriptions of the physical, emotional, and sexual abuse of Indigenous children draw attention to the harrowing histories of Canada’s residential schools, thus laying bare the necropolitical potential of settler-colonial dispossession. This essay links Wagamese’s narrative to recent arguments brought forward in Indigenous studies. It aims to demonstrate that Indigenous dispossession in settler colonial states is part of modernity, and its overarching political economy, that is capitalism.i