bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of Puerarin, Daidzein, Baicalin and Wogonin in Composite Preparations by Capillary Electrophoresis
Authors: Cunhong Li and Yan Xu Cunhong Li and Yan Xu
Published: August 2022

A simple method for the simultaneous determination of four bioactive components (puerarin, daidzein, baicalin, and wogonin) in composite preparations by microemulsion capillary electrophoresis with UV detection has been developed for the first time. A running buffer composed of 8% acetonitrile + 4% microemulsion(3.24% n-heptane + 13.24% sodium dodecyl sulfate (SDS) + 26.44% n-butanol + 57.08% distilled water in weight ratio) + 20 mM borax solution was found to be the most suitable for this separation. The limits of detection for four analytes were over the range of 0.50 - 1.2 μg ml-1. In the tested concentration range, linear relationships (correlation coefficients: 0.997 for baicalin, 0.997 for wogonin, 0.998 for daidzein and 0.999 for puerarin) between the peak areas and the concentrations of the analytes were obtained. This method has been successfully applied to simultaneous determination of the four bioactive components with recoveries from 94.6 to 106.3%.
Investigation of Acrylamide Based Hydrogels as L-Dopa and L-Tyrosine Drug Release System
Authors: dil Karaca A ar dil Karaca A ar
Published: August 2022

Acrylamide-based hydrogels exhibit significant volume migration in response to physical and chemical stimuli. These properties make their use as drug delivery systems widespread. In the study, acrylamide-based hydrogel structures were synthesized to be used as two prodrugs known as L-Dopa and L-Tyrosine carrier and release system. Fourier-transform infrared (FTIR) spectroscopy, scanning electron micrography (SEM), Image J program were used to evaluate the structure-property relationship of the synthesized hydrogels and swelling studies were performed. The maximum swelling capacity of the synthesized hydrogel structures was determined as 973.80and#177;12.25 %. The L-Dopa loading on the hydrogel was 69.51and#177;9.64% and the L-Tyrosine loading was 61.37and#177;5.08%. The release behavior of the drugs loaded on the hydrogel was monitored using a UV-vis spectrophotometer at pH 7.4 and λmax 280 nm. Accordingly, it was observed experimentally that 84.21and#177;1.71% of L-Dopa and 75.98and#177;2.69% of L-Tyrosine were released. The study is an alternative release system with the simultaneous release of L-Dopa molecule, which is especially used in the treatment of Parkinsonand#39;s disease, and L-Tyrosine, which plays an important role in the synthesis of L-Dopa.
Rotekstrakt av leggstokkrose og honning: lindrer hoste ved hjelp av mukobeskyttelse
Authors: Mueck Tobias
Published: August 2022

Den eksperimentelle studien undersøkte de bioadhesive egenskapene til hostesaft som inneholdt delvise fraksjoner av planteekstrakter, med eller uten tilsatt honning. Studieforfatterne fastslo at tilsetning av honning forlenget adhesjonstiden på slimhinnen i modellen, og dermed forbedret den fysiokjemiske lindringen av irritasjonen. Som en ytterligere lindrende virkning, reduserte de testede hostesaftene også slimhinnens gjennomtrengelighet for skadelige stoffer, noe som også ble forbedret ved tilsetning av honning.
ÜNIVERSİTE ÖĞRENCİLERİNİN MAHREMİYET BİLİNCİ
Authors: OZTURK Deniz , EYUBOGLU Gulcan , GÖÇMEN BAYKARA Zehra
Published: August 2022

Amaç: Bu araştırma, üniversite öğrencilerinin mahremiyet bilincini ortaya çıkarmak amacıyla tanımlayıcı olarak yapılmıştır.
Yöntem: Araştırmanın örneklemini, bir devlet üniversitesinde Hemşirelik, Fizik Tedavi ve Rehabilitasyon, Beslenme ve Diyetetik ile Mühendislik Bölümlerinde üniversite eğitimine yeni başlayan öğrenciler oluşturmaktadır (n=576). Araştırma verileri, Nisan 2021’de çevrim içi anket yoluyla Tanıtıcı Özellikler Formu ve Mahremiyet Bilinci Ölçeği kullanılarak toplanmıştır. Verilerin analizinde Mann-Whitney U ve Kruskal-Wallis testi kullanılmıştır.
Bulgular: Öğrencilerin Mahremiyet Bilinci Ölçeği toplam puan ortalaması 4,49±0,42’dir. Kadın öğrencilerin Mahremiyet Bilinci Ölçeği “kendine ait mahremiyet bilinci” alt boyut ortalama puanı ve toplam ölçek ortalama puanı, erkek öğrencilere göre istatistiksel olarak daha yüksektir. Sağlıkla ilgili bir ortaöğretim kurumunda eğitim alan öğrencilerin “Başkalarının mahremiyetini sürdürmek için davranışlar” alt boyutu ortalama puanı ve toplam ölçek ortalama puanı, diğer öğrencilere göre istatistiksel olarak daha yüksektir (p<0,05). Öğrencilerin en yüksek ortalama puanı “Mahremiyetimi kesinlikle korumak isterim.” (4,71±0,59), en düşük ortalama puanı “Toplu taşıma araçlarını kullanırken başkalarının telefonlarına bakmamayı alışkanlık haline getirdim.” (4,22±0,96) maddesidir.
Sonuç: Üniversite öğrencilerinin, yüksek düzeyde mahremiyet bilincine sahip olduğu saptanmıştır. Öğrencilerin kendi mahremiyetlerini korumaya ilişkin bilinci, başkalarının mahremiyetini korumaya yönelik bilince göre daha yüksektir. Üniversite eğitiminde, başkalarının mahremiyetini korumaya yönelik etkinliklerle öğrencilerin mahremiyet bilincinin geliştirilmesi önerilmektedir.
OBEZ BİREYLERDE SERUM FERRİTİN DÜZEYLERİ, İNSÜLİN DİRENCİ, METABOLİK SENDROM VE BESLENME DURUMLARI ARASINDAKİ İLİŞKİNİN RETROSPEKTİF ANALİZİ
Authors: ERÇAKIR Makbule , BAYRAM Sinem
Published: August 2022

Bu çalışmada, obez bireylerin beslenme durumlarının serum ferritin değerleri, insülin direnci ve metabolik sendrom ile ilişkisi bakımından retrospektif olarak incelenmesi amaçlanmıştır. Araştırmanın örneklemini Özel 19 Mayıs Hastanesi Beslenme ve Diyet polikliniğine 1 Ocak 2020’den itibaren başvurmuş 210 obez birey oluşturmaktadır. Bu bireylerin antropometrik ölçümleri, biyokimyasal bulguları, genel sağlık durumları ve beslenme durumları hasta dosyalarından kaydedilmiştir. Çalışmaya dahil edilen bireyler serum ferritin değerlerine göre; ferritin düzeyi ˂14,52 ng/mL ise kuartil 1 (Q1), 14,52-35,49 ng/mL ise Q2, 35,49-70,68 ng/mL ise Q3, ˃70,68 ng/mL ise Q4 olarak 4 gruba ayrılmıştır. Bireylerin beden kütle indeksi (kg/ m2) ferritin kuartillerine göre incelendiğinde Q2’de en yüksek beden kütle indeksi (32,5±6,4 kg/m2) gözlenmiştir (p˃0,05). Bel çevresi ölçümlerinde en yüksek bel çevresi ortalaması Q4’te olup (114,85±15,09 cm), kuartiller arasındaki fark anlamlı bulunmamıştır (p˃0.05). Bireylerin serum HOMA-IR ortalama değerleri en yüksek Q4’de (4,10±5,05) bulunmaktadır. HOMA-IR düzeyleri ferritin kuartiline göre istatistiksel açıdan önemli bulunmuştur (p˂0.05) Trigliserit değerleri Q4’te (169,43±93,40); HDL değerleri Q2’de (58,68±11,69); LDL değerleri ise Q4’te (127,21±35,15) en yüksek bulunmuştur. (˂0.05) Bireylerin ferritin quartillerine göre beslenme durumlarına bakıldığında protein tüketiminin en yüksek Q4’te olduğu (112,1±29,8 g/gün), karbonhidrat tüketiminin ise en yüksek Q1’de (395,2±83,6 g/gün) olduğu görülmüştür (p˂0.05). Obez bireylerin protein tüketimleri (g/gün) ile serum ferritin düzeyleri arasında pozitif yönlü orta kuvvetli bir ilişki tespit edilmiştir (r:0,506, p:0,000). Sonuç olarak yüksek serum ferritin konsantrasyonları yüksek trigliserit, yüksek LDL, yüksek HOMA, AST ve ALT değerleri ve daha düşük HDL değerleri ile ilişkilendirilmiştir. Obez bireylerde serum ferritinin yüksek olması insülin direnci ve metabolik sendrom için risk faktörü olabileceği belirlenmiştir. Bu risk faktörlerinden korunmak için obez bireylere yaşam tarzı değişikliği önerilmelidir.
Synergism of Beneficial Microbes Helps to Rejuvenate Flood and Landslide Affected Soils for Sustainable Agriculture – A Review
Authors: Haseena A , Gopal K Surendra
Published: August 2022

Climatic disasters, like floods and landslides, are the major causes for the decline in soil fertility or soilorganic matter. Soil organic matter influences the physical, chemical, and biological properties of soil; it isthe fundamental aspect that discloses soil health. Microorganisms in the soil environment participate acritical task in the enhancement of soil nutrients and soil fertility. Even though microbial bioinoculants arewidely studied for improving agriculture, the application of microbial consortium for the restoration oforganic matter or soil fertility in the flood and landslide depleted soils are yet to be exploited. The part ofliving biomass, i.e. soil microorganisms in restoring soil organic matter seems to be crucial, as microbes arethe major drivers in escalating organic matter in the soil. The living biomass recycles the nutrients in thesoil by utilizing the plant and animal litter in the soil and offers the crops adequate nutrients. Thus,microorganisms can force the accumulation of stable and chemically diverse soil organic matter in poorfertile soils. Exploring such vibrant, complex advantageous interactions among microorganisms seemsimperative to replenish organic matter exhausted soil. This article reviews the relevance of soil organicmatter, the role of soil microorganisms in improving soil organic matter and emphasizes the need forintensive research in raising beneficial microbiome for replenishing soil organic matter and thus to rejuvenatethe flood and landslide depleted soils to sustain agriculture.
Evaluation of water quality using physico-chemical parameters of Riverine Areas of Baddi (H.P), India
Authors: Sethi Vandana , Walia Yogesh Kumar , Rana Vishal , Gautam Divya
Published: August 2022

The present paper is focused on monitoring of surface water quality of Baddi area in Himachal Pradesh.The research work was carried out for the assessment of various physico-chemical parameters at twelvesampling location. A systematic study of fifteen physico-chemical parameters for water quality monitoringis done by evaluating - pH, electrical conductivity, turbidity, TDS, total hardness, major ions (Cl-, F-, NO3,SO42-, Ca2+, Mg2+, Na+, K+), biochemical oxygen demand (BOD) and chemical oxygen demand (COD). Theresults obtained were compared with the Bureau of Indian Standards (BIS: IS: 10500, 2012) guidelines. Itwas found that some of the parameters like electrical conductivity, turbidity, sodium, potassium, BOD andCOD are not in the permissible limit of the BIS. A strong correlation was observed between the industrialactivities and water pollution. The dense unplanned industrialization has negative effect on water qualityof the study area. Therefore, the strict compliance of regulatory standards should be followed for disposalof sewage and untreated effluents to protect water resources.
Effect of nitrogen and phosphorus fertilizers on growth and quality of high quality protein maize (Zea mays L.) to under South Saurashtra agroclimatic zone of Gujarat
Authors: Daroga Shiv Prasad , Vala G.S. , Choudhary Sheeshpal , Choudhary Mahendra , Hakla Chotu Ram
Published: August 2022

An experiment was conducted to assess the âeffect of nitrogen and phosphorus fertilizers on growth andquality of high quality protein maize (Zea mays L.) to under South Saurashtra agroclimatic zone of Gujaratâduring summer, 2016 at the department of agronomy, college of agriculture, JAU, Junagadh. The resultsrevealed that application of 150 kg N ha-1 significantly higher plant height, dry matter accumulation, numberof leaves per plant and protein content over control and 90 kg N ha-1, while at par with 120 kg N ha-1. Resultshowed that application of 60 kg P2O5 ha-1 significantly higher plant height, dry matter accumulation,number of leaves per plant and protein content, being remained at par with 45 kg P2O5 ha-1 over control.
Phytoplankton Groups in the Estuarine Mangrove Creeks of Edakochi (Kerala), Southwest Coast of India: A Preliminary Study
Authors: Nihal Davood , K.A. Aiswariya Ghosh , N.M. Naseem , M.P. Prabhakaran
Published: August 2022

The present work focused on the ecological studies in the mangroves of the Edakochi region, Kerala (India)with special reference to phytoplankton groups. This wetland is situated on the banks of Vembanad Lake,the largest Ramsar site of Kerala. Sampling was carried out from February to June 2017. 5 true mangrovespecies and 2 semi- mangrove species were noted from the Edakochi region. A total of 25 phytoplanktonspecies were recorded from different stations comprising 15 species of Bacillariophyceae, 7 species ofDinophyceae, 1 species of Cyanophyceae, 1 species of Chlorophyceae and 1 species of Ciliateae. In eachstation the species composition was found in an order of Bacillariophyceae > Dinophyceae >Cyanophyceae> Chlorophyceae >Ciliatae. Bacillariophyceae contributed 60% of the species, whereas Dinophyceaecontributed 28%. Cyanophyceae, Chlorophyceae and Ciliateae contributed 4% each. The highest numberof species (19) was recorded during March and the highest cell density was recorded during April (1143/l). The lowest cell density was recorded in June (844/l). From the study results, it was noted that the highestnumber of species in March was due to the favorably increased salinity. The shift in the salinity regime maybe the reason for the lowest number of species in June. Alternation in species diversity influences variousecosystem phenomenon, such as nutrient retention, primary productivity and vegetation dynamics. Thestudy findings depict good species diversity of phytoplankton in the Edakochi mangrove ecosystem.
Implementation of Small-Scale Biogas Plant in a Dairy Cattle Farm
Authors: Kaushik Purabi , Saharia J. , Bhattacharyya B.N. , Mili D.C. , Kalita D.
Published: August 2022

A biogas plant is an anaerobic digester that produces biogas from organic materials such as animal waste,sewage slurry, vegetable waste and others waste materials. Sahiwal Cattle Farm, College of veterinaryScience, AAU, Khanapara has developed a small-scale biogas plant in farm complex. The objectives of thisplant is to promote green technology and zero waste concepts on animal farming and to mitigate adverseeffects on the environment due to unsystematic management of animal waste disposal. The biogas producedis used as fuel for biogas stove, biogas water heater. Furthermore, the residual solid waste produced at theend of the process has been used as organic fertilizer in the fodder plot of the sahiwal farm complex.Although the hydro-carbons which are derived from direct chemical processes, bio-gas is produced througha bio-chemical process in which some bacteria convert the biological wastes into useful bio-gas comprisingmethane through chemical interaction. Such methane gas is renewable through continuous feeding ofbiological wastes and which are available in plenty in rural areas in the country. Since the useful gasoriginates from biological process, it has been termed as bio-gas in which methane gas is the main constituent.The gas which is produced by the above process in a bio-gas plant does not contain pure methane and hasseveral impurities containing methane, carbon dioxide, Nitrogen, Hydrogen, Carbon monoxide, Oxygenand Hydrogen sulphide.
Eco-Friendly customer engagement Practices in hotels: A Qualitative Study
Authors: Dar Shabir Ahmad
Published: August 2022

Hospitality industry especially hotels consume a good amount of natural resources and results in wastegeneration. Hotel Industry is considered as main customer oriented industry, were there is huge consumptionof energy resources. As we know that limited availability of energy resources on planet earth has made itessential feature of every industry and hospitality industry is not untouched to go for energy conservation.To contribute effectively, hotels have started exercising green practices which include reusing linen practices,natural temperature control techniques, 3Râs principle and many more. There is huge significance ofenvironment related issues that continues to rise in hotel industry because of increased knowledge aboutenvironmental issues. Keeping this information in mind, the current study stresses on exploring the ecofriendlycustomer engagement practices with respect to hotel location, hotel design exercised in hotels ofGulmarg, Kashmir as well as its impact on repurchase intention of services in hotels. A checklist wasdeveloped to receive data from the hotel managers/ supervisors. The outcome specified that someenvironmental friendly practices like plantation drives, walking through the wilderness, waste watermanagement tools, linen reuse, horse ridding as means of transportation, trekking through the green forests,use of natural light and installation of well designed ventilation and LED lighting etc are mostly exercisedpractices in the hotels of Gulmarg, Kashmir. The study revealed that eco friendly customer engagementpractices involve customers effectively and leaves an ever lasting impression on the customer and attractsthem again towards the destination.
Impact of certain granular and foliar insecticides on beneficial fauna in rice ecosystem
Authors: Bhavana D. , Verma N.R.G. , Malathi S. , Shravan Kumar R. , Kiran Babu T.
Published: August 2022

This study was conducted to investigate the effect of insecticides with different mode of actions and differenttoxicity levels against coccinellids and spiders in rice ecosystem at Regional Agricultural Research Station,Warangal during rabi, 2020-21 with the test cultivar Telangana Sona (RNR-15048). The selected granularand foliar insecticides viz., flubendiamide 0.7G, flubendiamide 20 WDG, cartap hydrochloride 4G, cartaphydrochloride 50 SP, chlorantraniliprole 0.4G, chlorantraniliprole 18.5 SC, fipronil 0.3G, fipronil 5 SC andcarbofuran 3G (check insecticide) were evaluated for their safety against the populations of Coccinellids and spiders in rice ecosystem. The insecticides were applied twice, i.e, granular formulations were appliedeither in nursery or 25 DATor both while spray formulations were used at 60 DAT (at panicle initiation tobooting stage). Out of 14 treatments, maximum population of beneficials (coccinellids and spiders) wereregistered in untreated control (T14) followed by carbofuran (T13) with 38.83% reduction, fipronil (T10, T11,T12) and chlorantraniliprole (T7, T8 and T9) ranging from 40.80 to 63.22% reduction whereas Flubendiamide (T1, T2 and T3) and cartap hydrochloride (T4, T5 and T6) were found to have greater impact on beneficialfauna (58.78 to 77.78% reduction over control). From the study it was evident that carbofuran, fipronil andchlorantraniliprole were found relatively safer to beneficial populations in rice ecosystem.
Dyslexia: Impact of mobile phones educational programs on academic achievement of elementary school dyslectic students of India and Sudan
Authors: Khatoon Khursheeda , Natamkar Hira Kulsum , Mohammed Sulafa Gewi , Anzar Humera , Khan Razia Aslam
Published: August 2022

Although mobile phones have emerged in large numbers in the past few decades, little is known about their impact. Especially the impact on the attitude and academic performance of DYSLECTIC students. Although people are becoming more and more interested in mobile devices and their relevance and consequences on children, the impact of related studies varies, and the overall effect remains unclear. The purpose of this study is to further investigate any differences that may exist: based on gender and school type; on the impact of mobile phone educational programmes on academic achievement of elementary school dyslectic students of India and Sudan.
Evaluation of the synergistic effect of cinnamon and probiotic filtrate against UTI
Authors: Aljeboury Ghydaa H.
Published: August 2022

This study was designed to evaluate the effects of cinnamon and probiotics both alone and in combination against pathogenic bacteria isolated from UTI patients. One hundred and ten male and female patients with a urinary tract infection (UTI) who visited private health care facilities were asked to provide urine samples. The urine samples were inoculated on Blood and MacConkey agars and incubated for 24 hrs. at 37 degrees Celsius. After 24 hours of incubation, no development was seen in the cultures, thus they were kept in the incubator for a further 48 hours. Gram staining was used to classify bacteria, and then conventional microbiological culture and biochemical properties were used to identify the isolates. Cinnamomum bark oil was extracted manually. Mueller Hinton (MH) agar plates were infected with 108 CFU/ml suspensions of microorganisms; this method was used to determine the agar disc diffusion test. Discs of sterile Whatman paper No. 3 impregnated with 10 g of the compounds were placed on top of MH agar that had been infected with bacteria. For 18 hours, the plates were kept at 37°C. Inhibition zones against the various bacterial strains were used to evaluate the antibacterial impact.
Evolution of IOT in health care by protecting and safeguarding private security in healthcare
Authors: Govindaraj M. , Murugeswari P. , Bharathiraja N. , Thiagarajan R. , Ahamed Inayath S. B. , Manikandan T.
Published: August 2022

Machines are being linked together in order to lessen the burden of medics in the near future while also offering effective services to patients. Furthermore, these gadgets generate a large amount of data during transmission. A clinical IoT based network is a networked system that must be protected from beginning to finish in order to function and communicate. To avoid sensitive data leakage from such devices/systems, connection should be encrypted. We are proposing dynamic encryption model which works well on health records generated from IoT machines.  Similarly, we ensure the security of the data through a two-way authentication system with the approval from agent/patient to access and share the data.
Assessing the efficacy of spironolactone on adult acne in subjects with polycystic ovary syndrome
Authors: Dewangan Bhuvaneshwari , Yadav Brijesh , Mishra Pratiksha , Kulmi Mohit
Published: August 2022

Aim: The present prospective clinical study was conducted to assess the long‑term spironolactone therapy and its effect with and without dietary‑induced weight‑loss, on insulin levels, lipid profile, and clinical features in females with PCOS (polycystic ovary syndrome). Methods: The present study included 22 females 12 normal weight and 10 obese within the age of 17-32 years having symptoms of PCOS including hyperandrogenism with clinical or biochemical evidence with amenorrhea and/or oligomenorrhea. These subjects were assessed before spironolactone therapy and after 100mg/day spironolactone orally for 12 months. Lifestyle modification was advised for obese females. Before starting and following antiandrogen therapy, metabolic, endocrine, and clinical parameters were assessed. Results: Spironolactone orally resulted in a significant reduction of triglycerides in overweight females and an increase in HDL (high-density lipoproteins) in subjects who were lean and have normal weight. After 12 months of oral spironolactone therapy, the area under the curve of insulin, insulin resistance with hemostasis model, and levels of insulin during OGTT at 60 minutes were significantly reduced in obese females. In females with PCOS following therapy, no negative change in insulin sensitivity and secretion and weight loss was seen after pharmacologic treatment.
Do acontecimento à luta: uma análise sobre o movimento Mães de Maio como uma ação coletiva conflitual
Authors: Alves Thaís Da Rosa
Published: August 2022

O presente artigo propõe refletir sobre a construção de uma ação coletiva conflitual e a sua transformação em um movimento social duradouro a partir do modelo proposto por Guy Bajoit e Julien Vanhulst (2016). Para tal análise foi escolhido o movimento das Mães de Maio, coletivo composto por mulheres oriundas das camadas populares que perderam seus filhos nos denominados Crimes de Maio, que ocorreram em 2006 no estado de São Paulo. Foram analisadas, a partir de um levantamento documental de materiais disponibilizados na internet sobre o movimento, algumas estratégias adotadas pelo grupo em consonância com as condições propostas pelos dois autores com a finalidade de verificar se tais proposições se enquadravam no movimento social selecionado.
Error Analysis on EFL Students’ Thesis Proposal Writing
Authors: Octaberlina Like Raskova , Muslimin Afif Ikhwanul
Published: August 2022

The present research was intended to analyse the errors made by the university students, especially the students in the eight semesters who write thesis proposals. Hence, the main objective of the present research was to investigate types of errors as well as to know the dominant errors which were existed in students’ thesis proposal compositions. This research employed descriptive quantitative study by calculating the number of errors by percentage. There are 42 participants from English Education Department in one of public university in West Nusa Tenggara, Indonesia. The results showed that there were 195 errors consisting of 71 (36%) addition errors, 64 (33%) misformation errors, 48 (25%) omission errors, and 12 (6%) misordering errors. The most dominant errors as shown by the percentage were students tended to add more than the structure or grammar needs. Students overgeneralized to use affix –s in verb and to use double auxiliaries (be, are, is). These results suggest that the instructor needs to help students on understanding and practicing more to fix the errors.
Perceived Value and Perceived Quality on Repurchase Intention: The Case Study Of Spotify in Bandung
Authors: Tarmidi Didi , Santoso Anton Budi , Marinda Vina Silviani , Amalia Shendy
Published: August 2022

The rapid development of digital music applications in Indonesia is an opportunity for digital music application providers to meet the needs and desires of the community. One of them is the Spotify app. The problem is based on the number of Spotify Freemium users than Spotify Premium and the start of many new digital music applications that are starting to emerge, this is a challenge for Spotify is increasing its repurchase intention. The research method used in this study is a quantitative method with a descriptive type of research. Sampling was carried out using a non-probability sampling technique used was purposive sampling with a total of 400 respondents using the Spotify application in Bandung City. Meanwhile, the data analysis techniques used are descriptive analysis and multiple linear regression analysis. The results of the study based on descriptive analysis for the perceived value variable are already in the excellent category by 89%, the perceived quality variable is already in the excellent category by 88%, and the intention repurchase variable is already in the excellent category by 89%. Perceived value and perceived quality have a positive and significant effect on repurchase intention with a magnitude of influence of 48.1% and the remaining 51.9% influenced by other factors that were not studied.
SOCIAL INNOVATION AND HIGH-QUALITY COCOA PRODUCTION: A CASE STUDY OF THE "˜CACAU SUL BAHIA' NETWORK
Authors: Santini Pigatto Giuliana Aparecida , Brunori Gianluca , Estival Katiany Gomes Santana , Lourenzani Ana Elisa Bressan Smith , Moraes Nelson Russo de
Published: August 2022

This study aimed to analyze whether the formation of the "˜Cacau Sul Bahia' Network promoted social innovation in southern Bahia, Brazil. Data were collected through participant observation, document analysis, and semi-structured interviews with 8 institutions and 10 cocoa producers who are members of the Cacau Sul Bahia Association (CSBA). Social network data were analyzed using UCINET. The approaches of social innovation, territorial development and social networks were the basis for the analyzes. The results showed that "˜Cacau Sul Bahia' Network promotes some aspects of social innovation, such as cooperation, social governance, collective efforts and trust building. Although the main goal of Network is to improve the quality of cocoa beans and add value to local chocolate, its effects reach much farther. The "˜Cacau Sul Bahia' Network formation, with the creation of the Cacau Sul Bahia Association leveraged the cultural value and historical importance of cocoa in the region, which has recently been granted geographical indication protection. Actors participating in the "˜Cacau Sul Bahia' Network contribute to territorial development in southern Bahia. Personal and professional ties between actors are strong and play an essential role in the success of the association. However, strengthening the social capital is needed to reinforce the process of social innovation more broadly. This empirical research provides scientific and technical contributions about social innovation, high-quality production systems and geographical indication protection in a developing country, showing that social dialogue, community governance, and collective efforts can stimulate sustainable development and quality improvement in disadvantaged rural areas.
Implementation of Automation and Industry 4.0 Technologies in Automotive Manufacturing Companies
Authors: Smolka Dávid , Papulová Zuzana
Published: August 2022

Industry 4.0 technologies have been disrupting the automotive industry for the past few years. The changes bring shift in the established paradigm and automotive sector has taken a leading role in implementing various elements of this revolution. Mar- gins from selling new vehicles are considered very low, so companies understand the importance of innovation and efficiency improvements. In our research, we explore the most relevant technologies connected to automation and Industry 4.0 in automotive industry with purpose to find deeper connections in obtained information. The aim of our research was also together with production managers and/or process managers to evaluate the level of components and technologies within the concept of Industry 4.0 and automation implemented in automotive manufacturing companies’ operations in Slovakia. Results point to high level of application of automation technologies within the automotive industry and to positive correlation between the level of implemen- tation of elements of advanced automation and the number of implemented base technologies within the key supporting technologies of Industry 4.0.
Serological and molecular detection of Macrophomina phaseolina, causing root rot of Citrus reticulata
Authors: Chakraborty Biswanath , Chakraborty Usha , Rai Kuldip , Sumar Kiran , Dey Pannalal
Published: August 2022

Polyclonal antibodies (PAbs) were raised against mycelial antigens of Macrophomina phaseolina a causal organism of root rot disease of mandarin plants. IgG was purified and further packaged into immunological formats such as immuno diffusion, Plate trapped antigen (PTA)-ELISA, dot immunobinding assay, Western blot analysis and indirect immunofluorescence for quick and accurate detection of pathogen from soil. Indirect staining of mycelia and sclerotia of M. phaseolina with homologous PAb and labeling with goat antirabbit IgG conjugated with FITC developed strong fluorescence in young hyphal tips and sclerotia of M. phaseolina. Genomic DNA prepared from mycelia of M. phaseolina was purified and PCR amplification of 18S rDNA was done using ITS region specific primer pair. The amplified DNA was sequenced and aligned against ex-type strain sequences from NCBI GenBank using BLAST and phylogenetic analysis was obtained using MEGA4 software. Amplification of ITSI region of the rDNA can be considered as a rapid technique for identifying pathogens successfully in all cases.
Effect of copper on seed germination, root elongation and shoot elongation of seedlings of commercially cultivated tea varieties
Authors: Mandal Sima , Saha Aniruddha , Saha Dipanwita
Published: August 2022

Tea (Camellia sinensis L. (0.) Kuntze) is an economically important plantation crop of India but is prone to attack by several fungal pathogens. Copper based fungicides are being used for decades to control fungal disease in tea which may lead to accumulation of copper in the soil. The aim of the present work was to investigate toxic effect of Cu+2 on seed germination, growth and morphological changes in tea seedlings. Different concentration of copper sulphate was applied on three different commercially cultivated tea varieties (TS-462, TS-520 and TS-463). The effect of different concentrations of copper (0.5 – 8 mM) on seed germination, root elongation and shoot elongation of the tea plant were evaluated. Percent germination was found to decrease progressively with increasing concentrations of Cu+2. Maximum reduction of seed germination was showed by TS-463. Several damaging effects such as reduced root hair proliferation, structural deformation and reduction in length of root and shoot were observed when the germinated seedlings were allowed to grow at higher concentrations of copper solutions. Decrease in the dry mass of both root and shoot were also recorded. The results showed that excess copper have negative effect on germination of tea seeds and subsequent growth of the seedlings.
O uso do core set da CIF para avaliação de pacientes com distúrbios cardiorrespiratórios.
Authors: Camelo de Silos Bertoldo Caroline , Riedi Daniel Chistiane , Stockler Gustavo Athayde , Fréz Andersom Ricardo , Pegoraro Baroni Marina , Ruaro João Afonso
Published: August 2022

Introdução: A Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF) categoriza a saúde e deficiência do indivíduo considerando a funcionalidade e os fatores contextuais. No entanto, a CIF apresenta muitas categorias que dificultam o seu uso diário e, por isso, foram criados os core sets. Entre os diversos core sets propostos, existe um core set para condições cardiorrespiratórias pós-agudas. Objetivo: classificar os pacientes com alterações cardíacas, respiratórias e mistas, assistidos ambulatoriais por meio de um core sets para esta população, além de verificar se existem diferenças entre os grupos na aplicação deste core set. Métodos: Foram avaliados indivíduos com diagnóstico clínico de doenças cardiorrespiratórias em acompanhamento fisioterapêutico ambulatorial para reabilitação cardiopulmonar. A amostra foi dividida em três grupos: cardíacos, respiratórios e mistos. Os pacientes foram avaliados por meio da versão abreviada do core set para condições cardiorrespiratórios pós-agudas, funcionalidade, força de preensão palmar e dos músculos respiratórios. Resultados: A amostra foi composta por 67 indivíduos alocados de acordo com seu comprometimento. Verificou-se que apenas as funções de energia e impulso, cardíaca e de ingestão, estrutura do sistema respiratório e a atividade andar apresentaram respostas significativamente diferentes entres os grupos. Pacientes com distúrbios respiratórios, cardíacos e mistos apresentam perfis funcionais semelhantes, porém as categorias com diferença desse perfil foram as relacionadas ao sistema respiratório, atividades e funções relacionadas ao aumento da demanda metabólica como andar. Conclusão: Assim é possível afirmar que o core set auxilia a identificar as disfunções dos pacientes sem depender se sua disfunção é cardíaca, respiratória ou mista que pode ser uma ferramenta utilizada no meio clínico.
Self-Selected COVID-19 “Unvaccinated” Cohort Reports Favorable Health Outcomes and Unjustified Discrimination in Global Survey
Authors: Verkerk Robert , Kathrada Naseeba , Plothe Christof , Lindley Katarina
Published: August 2022

Self-reported data collected independently by the UK-based Control Group Cooperative between September 2021 and February 2022, inclusive, from a self-selected international COVID-19 “unvaccinated” population are discussed. Data come from a cohort of 18,497 participants who provided questionnaire responses monthly. The largest numbers are from Europe, North America, and Australasia. Data were skewed towards the 40-69y age range and included 60% female respondents. Reasons for avoiding COVID-19 “vaccines” were: a preference for natural medicine, distrust of pharma, distrust of government information, poor/limited trial data, and fear of long-term adverse reactions. During the survey period, the greatest incidence of COVID-19 disease was reported in the 50-69y range, peaking at 12.3%, in January 2022.  Persons at 70y and above were least affected (1.3%), with 10.7% and 3.8% in the 20 to 49y band, and in the 1 to 19y group, respectively. Most rated their symptoms as “mild” (14.4%), with 2% reporting “severe” disease. Fatigue, cough, muscle/body aches, and fever were the four most common. Just 0.4% of the cohort reported hospitalization (as in- or out-patients). Nearly two-thirds reported taking vitamin D, C, zinc, quercetin, or a combination, for prevention, with 71% using vitamin D, C, and zinc for treatment. Nearly 45% reported “moderate” to “severe” mental health issues (depression) during the survey period. Menstrual abnormalities were reported by 36% of women in the 20-49y age band. Reported job losses were greatest in Australia and New Zealand at 29%, followed by 13% in North America. Between 20% and 50% reported being personal targets of hate because of their vaccination status. Between 57% and 61% of respondents in Southern Europe and Western Europe, Australia/New Zealand and South America, reported being targets of governmental victimization. The cohort may not be representative of wider populations given its reliance on self-care. The findings suggest that opting out of the world’s largest medical experiment, relying on natural immunity, self-care with supplements, and/or ivermectin or hydroxychloroquine, appeared to contribute to low incidences of severe disease, hospitalization, or death. The results imply the urgent need for prospective studies of “unvaccinated”, “partially vaccinated”, and “fully vaccinated” persons investigating long-term outcomes, behaviors, choices, and discriminatory responses by the state, institutions, or employers based on “vaccination” status. Public dialogue about the touted “safety and effectiveness” of vaccines, contrasted with strategies to enhance immune resilience, all in the context of authoritarianism versus autonomy, self-care, personal responsibility, and freedom of choice is needed.
Implementation of Compliance with Non-Smoking Area Policy at Rejosari Health Center, Tenayan Raya District, Pekanbaru City
Authors: Mutiara Yuri Indah , Widodo M.Dedi , Abidin Zainal , Hanafi Ahmad , Kamal Yanwir
Published: August 2022

To realize the highest degree of health and realize a healthy Indonesia and reduce the number of conscientiousness caused by cigarettes, the government issued a Joint Regulation of the Minister of Health and Minister of Home Affairs No.188 / Menkes / PB / I / 2011 No. 7 of 2011 concerning Guidelines for Non-Smoking Areas. And the Mayor of Pekanbaru issued a regulation on non-smoking areas, namely number 39 of 2014. The researcher's problem is how to implement the KTR policy at the Rejosari Health Center in Pekanbaru City. This study aims to determine the Implementation of Compliance with the No Smoking Area (KTR) Policy at the Rejosari Health Center, Tenayan Raya District, Pekanbaru City in 2022.The type of research carried out is qualitative with a descriptive method, a scientific approach to which the phenomenological approach is used. The data collection method was carried out by observation and in-depth interviews with 7 informants, namely the head of the Public health center, Public health center officers, security, and visitors. The results of this study show that the implementation of compliance with the No Smoking Area Policy at the Rejosari Health Center has not been carried out properly. the implementation of socialization that has not been effective to officers and visitors which makes the lack of public knowledge about KTR in Public health center, and there is no Special Team to supervise the Public health center environment, the readiness of the implementer has not fully demonstrated an attitude that supports the policy of non-smoking areas in puskesmas, there are still findings of visitors who smoke in the Public health center environment this is because there is no strict sanction from the Public health center. and have not prepared guidelines and commitments. It is recommended to the Head of the Rejosari Health Center to provide knowledge to all officers and visitors of the Rejosari Health Center in Pekanbaru City regarding the No Smoking Area at the Public health center, conduct socialization, form a special KTR Team and make strict sanctions, namely making written regulations and making commitments.
Scientometric Analysis of Global Scientific Publications on COVID-19 and Diabetes with an Emphasis on Middle Eastern Countries
Authors: Atlasi Rasha , Tabatabaei-Malazy Ozra , Bandarian Fatemeh , Rezaei Nafiseh , Khashayar Pouria , Larijani Bagher
Published: August 2022

Background: Due to the worldwide spread of COVID-19, various countries have designed scientific studies on different aspects of the disease. Patients with diabetes mellitus (DM) have been proven to be at higher risk of COVID-19-related complications, hospitalization, and death. Objectives: The aim was to conduct a scientometric analysis of scholarly outputs on diabetes and COVID-19. Methods: Web of Science was searched for scientific publications on diabetes and COVID-19 by Middle Eastern researchers until September 14, 2021. Collected data were analyzed for document type, subject area, countries, top journals, citation number, and authors’ collaboration network using VOS viewer 1.6.15 and bibliometrix R-package 4.1.1. Results: Overall, the characteristics of 603 documents on DM and COVID-19 were analyzed. The top three productive countries in the field were Iran, Turkey, and Saudi Arabia. The top affiliation was from Iran; “Tehran University of Medical Sciences” (n = 168), followed by "Shahid Beheshti University of Medical Sciences" (n = 82). The total citation number was 3704 times. The highest cited paper (348) was a systematic review from Iran, published in arch Acad Emerg Med. The top source was "Diabetes & Metabolic Syndrome: Clinical Research & Reviews," with 26 documents. Conclusions: The current study provides an overview of the quantity and quality of published scholarly documents on the intersection of DM and COVID-19 in the region. Our findings help scientists find the existing gaps, manage the research budgets, identify active authors and scientific institutes to collaborate with, and use their experience to produce new knowledge in the future.
Energy Aware Stable Multipath Disjoint Routing Based on Accumulated Trust Value in MANETs
Authors:   Dept. Of Computer Science & Engineering, Jawaharlal Nehru National College of Engineering, Shivamogga, Karnataka, INDIA, S M Benakappa , M Kiran
Published: August 2022

Conserving energy and finding the stable path are the two vital issues in Mobile Ad Hoc Networks (MANETs) as the prior increases the network lifetime and the later increases the network throughput. The nodes which are not legitimate in terms of residual energy and packet forwarding history might be a threat to the path thereby making the path unstable. Thus, it results in frequent link failure, reduced throughput, reduced network and path life time. In order to reduce these hazards, authors have proposed an energy efficient, reliable path selecting protocol referred to as Trust Based Energy Aware Multipath Disjoint Routing Protocol (TEA-MDRP) for MANETS in this article. TEA-MDRP finds the optimum route between the source and the destination nodes using two parameters namely, the Accumulated Trust Value (ATV) and the node’s residual energy (N_res). ATV is calculated based on the packet forwarding status of the node which shows how good the node is in terms of packet forwarding point of view. TEA-MDRP allows only the nodes which have a good ATV and sufficient residual energy. A good ATV shows loyalty in forwarding the packets while a sufficiently large residual energy node avoids frequent path breakups and packet drops. Thus, the TEA-MDRP not only increases the network and path lifetime but also increases the throughput of the communication. Further, with the legitimate nodes in the paths, the TEA-MDRP considerably reduces the control packet overhead which might occur because of the frequent route re-discovery process. An extensive simulation is carried out using Network Simulator-2.35 for the quantitative and qualitative analysis of TEA-MDRP. The results obtained are compared with classical AOMDV and the results are satisfactory.
A diachronic view of the development of solfeggio teachings in Republic of Serbia
Authors: Pindović Bogdan
Published: August 2022

The path to establishing a specialized music education with solfeggio teaching, as a necessary subject for acquiring primary, and then secondary and higher musical education, was a difficult one due to the historical turmoil on the territory of Serbia and its' overall significant lag behind the rest of Europe in many aspects of national, cultural and educational development. Bearing in mind the lack of musically educated staff and the absence of a national composition practice, which would pave the way and open the door to the institutionalization of music education, the question of the origin of the national solfeggio school and its development arises. The aim of the paper is to observe the critical moments in the development of solfeggio teaching in the Republic of Serbia, including the actions of personalities from the field of music pedagogy spaning from the nineteenth century till present day, with particular reference to the most prevalent methodological approach.
Structures of topoisomerase V in complex with DNA reveal unusual DNA-binding mode and novel relaxation mechanism
Authors: Osterman Amy , Mondragón Alfonso
Published: August 2022

Topoisomerase V is a unique topoisomerase that combines DNA repair and topoisomerase activities. The enzyme has an unusual arrangement, with a small topoisomerase domain followed by 12 tandem (HhH)2 domains, which include 3 AP lyase repair domains. The uncommon architecture of this enzyme bears no resemblance to any other known topoisomerase. Here, we present structures of topoisomerase V in complex with DNA. The structures show that the (HhH)2 domains wrap around the DNA and in this manner appear to act as a processivity factor. There is a conformational change in the protein to expose the topoisomerase active site. The DNA bends sharply to enter the active site, which melts the DNA and probably facilitates relaxation. The structures show a DNA-binding mode not observed before and provide information on the way this atypical topoisomerase relaxes DNA. In common with type IB enzymes, topoisomerase V relaxes DNA using a controlled rotation mechanism, but the structures show that topoisomerase V accomplishes this in different manner. Overall, the structures firmly establish that type IC topoisomerases form a distinct type of topoisomerases, with no similarities to other types at the sequence, structural, or mechanistic level. They represent a completely different solution to DNA relaxation.
Local field potentials reflect cortical population dynamics in a region-specific and frequency-dependent manner
Authors: Gallego-Carracedo Cecilia , Perich Matthew G , Chowdhury Raeed H , Miller Lee E , Gallego Juan Álvaro
Published: August 2022

The spiking activity of populations of cortical neurons is well described by the dynamics of a small number of population-wide covariance patterns, whose activation we refer to as ‘latent dynamics’. These latent dynamics are largely driven by the same correlated synaptic currents across the circuit that determine the generation of local field potentials (LFPs). Yet, the relationship between latent dynamics and LFPs remains largely unexplored. Here, we characterised this relationship for three different regions of primate sensorimotor cortex during reaching. The correlation between latent dynamics and LFPs was frequency-dependent and varied across regions. However, for any given region, this relationship remained stable throughout the behaviour: in each of primary motor and premotor cortices, the LFP-latent dynamics correlation profile was remarkably similar between movement planning and execution. These robust associations between LFPs and neural population latent dynamics help bridge the wealth of studies reporting neural correlates of behaviour using either type of recordings.