bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of an Android-Based Physics Interactive E-Module Equipped with Problems with Scaffolding in Applying the Concept of Light Waves
Authors: Alvia Quthrotun Nada  , Taqwa Muhammad Reyza , Supriana Edi , Suwasono Purbo
Published: October 2022

The purpose of this study was to develop and determine the validity and practicality of learning media in the form of an Android-based E-Module equipped with questions with scaffolding on light wave material. In this study, the Research and Development (R&D) model with the 4-D method was used. The stages of 4D development include define, design, develop, and disseminate, but in this study only up to the design stage with validity and practicality tests. Product validation was carried out by three media and material expert validators, namely 1 lecturer and 2 high school physics teachers, while the practicality test was carried out by 48 students of class XI MIPA SMAN 1 Paciran. The research results obtained quantitative and qualitative data. Analysis of quantitative data using percentages and categorized criteria of validity and practicality. The results of this research and development are in the form of an Android-based physics interactive E-Module product with light wave material. From the validation test by the validator, the average percentage of results for media and material validation is 90% with very valid criteria. This shows that the material presented is in accordance with the curriculum so that it can support student learning. In the validation test results of practice questions with scaffolding, the average percentage is 97% and the percentage of evaluation questions is 96% with very valid criteria. This shows that the practice questions and evaluation questions that have been made valid are used by students in studying light waves and are validly included in the developed e-module. From the results of the practicality test, an average percentage of 85% was obtained in the very practical category. This shows that the product developed is very valid and very practical so it is worth investigating its effectiveness so that it can further support physics learning in understanding the concept of light waves, both used independently and in school learning.
Students' Learning Difficulties And Their Relationship With Biology Learning Outcomes Of Class XI Students at SMA N 8 Padang During Online Learning
Authors: Sinaga Chairunnisa , Gusmaweti Gusmaweti , Azrita Azrita , Deswita Lisa
Published: October 2022

his research is motivated by students who have difficulty in the online learning process is the low learning outcomes obtained from students. This study aims to analyze what factors influence the biology learning difficulties of students in class XI IPA at SMA Negeri 8 Padang during online learning and to determine the relationship between students' learning difficulties in biology through online learning and student biology learning outcomes. This research is descriptive research. The population of this research is class XI IPA which consists of 3 classes totaling 110 students. The research sample amounted to 33 students. The sampling technique is a random sampling technique with a sample proportion of 30%. The research data were analyzed using descriptive analysis and then a t-test to determine the correlation. The results showed that the highest score of the student learning difficulty factor was 2.81, namely the motivation and interest in student learning factors, and the lowest difficulty factor obtained a score of 2.44, namely social interaction. There is a relationship between students' learning difficulties in biology through online learning with biology learning outcomes with a value of r = 0.520; the coefficient of tcount value of 4.642 is greater than ttable of 2.040, so it can be concluded that there is a positive and significant relationship between learning difficulties in biology through online learning and student learning outcomes and there are suggestions for schools to be positive inputs in efforts to build and improve models. online/online learning and is also able to improve student learning and it is hoped that teachers and parents can recognize and observe online learning difficulties experienced by these students.
Estágio em Medicina de Família e Comunidade em unidades com residência médica no município do Rio de Janeiro
Authors: Tiseo Thaís Ranzani , Santos Marcia Cristina Lemos dos , Smiderle Clarice de Azevedo Sarmet Loureiro
Published: October 2022

Introdução: Atualmente os estudantes de Medicina devem cumprir 30% de seu estágio obrigatório no Sistema Único de Saúde, na atenção primária e em serviço de urgência e emergência. No Rio de Janeiro, as principais instituições de ensino adequaram seus currículos a essa exigência e o internato em Medicina de Família e Comunidade passou a ocupar grande parte dessa carga horária. Objetivo: Este trabalho propõe-se a investigar como esse estágio, realizado em unidades com residência de Medicina de Família e Comunidade (MFC) na cidade do Rio de Janeiro, impacta a formação de futuros médicos, identificando quais os principais fatores envolvidos, quais as potencialidades desse estágio e sua influência, tanto pessoal como social, sobre os estudantes. Métodos: Foi realizado um estudo qualitativo, e a coleta de dados ocorreu por meio de minigrupos focais com alunos de uma universidade federal que vivenciaram o internato em Medicina de Família e Comunidade em unidades nas quais programas de residência estão implementados. A análise temática foi posteriormente realizada seguindo os preceitos de Bardin. Resultados: Na análise de dados, foram estudadas seis categorias: expectativas prévias em relação ao estágio e à MFC, impressões atuais sobre o estágio e a MFC, aprendizados diversos de outras especialidades, vivências que aproximam da MFC, vivências que afastam da MFC e aprendizados extra-acadêmicos. Conclusões: Com deste estudo foi possível identificar, por meio da percepção dos estudantes, os pontos fracos e fortes da realização de estágio em unidades com residência médica em MFC na cidade do Rio de Janeiro e como essa vivência impacta a formação dos acadêmicos. Pelo potencial demonstrado, sugere-se incentivo e investimento nesse tipo de estágio.
La leyenda del 20º convoy Malinas-Auschwitz. Historia, memoria y controversia en torno a un importante acontecimiento de la Resistencia belga
Authors: Bénit Spinewine André
Published: October 2022

A principios de 2021, la periodista y escritora belga Évelyne Guzy publica La maldición de las palabras, un relato histórico acerca de las dos ramas de su familia judía de la que varios miembros fueron deportados de Malinas a Auschwitz durante la Segunda Guerra Mundial. La tercera parte, «El luchador de la resistencia», está dedicada a la figura heroica y la personalidad controvertida de su abuelo materno Roger-David Katz. De hecho, el descubrimiento tardío de documentos a los que tiene acceso le permite ver que en la mitología familiar hay cosas que no «encajan», principalmente sobre la posible participación de su héroe en el episodio del vigésimo convoy, un episodio controvertido y profundamente arraigado en la memoria de la Resistencia belga. En este ensayo, a la luz de los estudios que se le han dedicado, tratamos de hacer un balance de este asunto y de comprender las razones que empujan a Guzy a volver hoy sobre este acontecimiento convertido en leyenda.
El diseño del centro político en Menorca como proyecto de construcción democrática. 1975-1977
Authors: Sánchez Socías Beatriz
Published: October 2022

This article analyses the creation of Unión de Centro Democrático (UCD) on the island of Menorca from Franco’s death until the configuration of the political parties shortly before the 1977 elections. Through documents from local and private archives, the press of the time and the testimonies of different political protagonists of the Menorcan process, the construction of a political formation that became the majority party in this constituency and in the whole of Spain is studied. In the case of Menorca, it is concluded that the centrists’ action was particularly important due to their leadership in promoting the articulation of Balearic pre-autonomy, which was assumed on the island as something inseparably linked to the achievement of democracy. This common goal of self-government gave rise to a unanimous consensus among all ideological sectors, from the conservative centre to the most progressive left, so that it was the Menorcan political elite that began to set the guidelines in the Balearic archipelago on pre-autonomy institutionalization, led by the UCD of Menorca.
Reseña de: Rújula, Pedro & Frasquet, Ivana (coords.): El Trienio Liberal (1820-1823). Una mirada política
Authors: Gilarranz-Ibáñez Ainhoa
Published: October 2022

Reseña de: Rújula, Pedro & Frasquet, Ivana (coords.): El Trienio Liberal (1820-1823). Una mirada política. Granada, Comares, 2020, pp. 601, ISBN: 9788490459768.
Reseña de: Cerón Torreblanca, Cristián (coord.): Españolas. Biografías femeninas y recursos didácticos para una historia de España Contemporánea
Authors: Ortega Muñoz Víctor José
Published: October 2022

Reseña de: Cerón Torreblanca, Cristián (coord.): Españolas. Biografías femeninas y recursos didácticos para una historia de España Contemporánea. Oviedo, Trabe, 2021, 316 pp., ISBN: 978-84-18286-38-4.
Mucocutaneous leishmaniasis
Authors: Bendaoud Layla , Hocar Ouafa , Amal Said
Published: October 2022

Leishmaniasis is a parasitosis caused by protozoa of the genus Leishmania (L.) transmitted by the bite of the sandfly Phlebotomus [1]. In Morocco, there exist three species: L. infantum, L. major, and L. tropica, most often responsible for the cutaneous and visceral forms. Mucosal involvement is rare and responsible for invasive, destructive, and treatment-resistant lesions [2]. Herein, we report a case of mucocutaneous leishmaniasis with different epidemiological and clinical characteristics from those of the New World. A nineteen-year-old female patient from the South (Essaouira, Morocco), without any particular personal history, with a father treated for cutaneous leishmaniasis one year ago, consulted for cutaneous and mucosal lesions that appeared eight months previously, painless, non-pruritic, beginning with an erythematous papule that progressively increased in size, with an ulcerated surface and an infiltrated base, two on the lower lip (Fig. 1a), and ten distributed between both forearms (Fig. 1b) and both legs. Direct examination for Leishman bodies was positive on the two oral mucosal lesions and one skin lesion. HIV serology was negative. The patient received meglumine antimoniate for twenty-one days, combined with cryotherapy sessions, with a good evolution without any detectable side effects.
Neutrophil-lymphocyte Count Ratio as Section an Indicator of Culture Positive versus Culture Negative Sepsis: A Singlecentre Cross-sectional Study
Authors: Minni Meka , Kumar G Rakesh , Prasad BN Raghavendra , Raveesha A
Published: October 2022

Introduction: In sepsis patients, the Neutrophil-lymphocyte Count Ratio (NLCR) is a laboratory statistic that can indicate bacterial infection. Aim: To measure NLCR in patients with sepsis and compare the NLCR in patient with culture positive and culture negative sepsis. Materials and Methods: This single-centre, cross-sectional study was conducted in the Department of General Medicine at R.L. Jalappa Hospital (Sri Devaraj URS Medical College), Kolar, Karnataka, India, from October 2021 to December 2021. A total of 120 patients above 18 years of age with sepsis, diagnosed as per the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3), were included in the study. Participants were evaluated for sepsis and septic shock (society of critical care medicine conference definitions) the principles of initial resuscitation (fluid therapy, vasopressors, inotropic support), and infection issues (source identification and control, appropriate antibiotic therapy) were followed regularly and the outcome studied. Neutrophil count, lymphocyte count, and calculation of NLCR were done at the time of admission. The correlation studies of NLCR in culture-positive and culturenegative was done and compared. Data was analysed by using coGuide software (version 1.03). Results: The mean age of patients was 58.98±17.78 years, ranged from 20 to 96 years, 47 (39.17%) were male and 73 (60.83%) were female, majority 93 (77.50%) out of 120 patients had fever. Majority 78 (65%) had type 2 diabetes mellitus. Neutrophilto-Lymphocyte ratio (NLR) was 10±1.67, ranging from 7.40 to 14.50. The area under the ROC curve was 0.522. There was no statistically significant relationship between the NLCR and culture report (p-value=0.216). The NLCR had poor predictive validity in predicting culture positive, as indicated by the area under the curve {0.522 (95% CI: 0.417 to 0.626, p-value= 0.988)}. Conclusion: NLCR can be considered as predictor for the initiation of treatment of patients with sepsis.
Non-syndromic Concomitant Hypo-Hyperodontia in the Anterior Region of MandibleAn Extremely Rare Phenomenon: Literature Review with Recent Updates
Authors: Abdyli Resmije Ademi , Abdyli Genc , Berisha Nora , Agani Zana , Ahmedi Jehona
Published: October 2022

Introduction: Hypo hyperdontia is a numeric mixed anomaly in which teeth may be supernumerary or absent, relative to the normal complement. The occurrence of this condition in the same individual is termed “Concomitant Hypo-Hyperdontia” (CHH). The presence of CHH in the same dental arch is uncommon, especially when it occurs in the front of the mandible in a Nonsyndromic Concomitant Hypo-Hyperdontia (NCHH). Aim: To conduct a literature review of the published articles in the English language, regarding NCHH in the anterior region of the mandible covering the period from October 1977 to December 2021. Materials and Methods: An extensive electronic search was conducted in February 2022, from Google Scholar, PubMed, and Elton B. Stephens Company (EBSCO) databases, using keywords such as mandible, hypodontia, hyperdontia and nonsyndromic. Manual sorting of the preselected literature, revealed only 19 published papers concerning NCHH in the frontal region of the mandible, spanning a period of 44 years. Results: The review analysed the data from 19 published studies, which presented 24 affected patients with a mean age of 12.36 years, with a male/female ratio of 1:1, involving a total of 41 missing teeth, including bilateral mandibular central incisors at 66.66%, followed by missing unilateral central incisor at 29.16% and 1 case (4.16%) displaying absence of both lateral incisors. Regarding 25 presented supernumerary teeth (ST), 72% of cases presented single midline ST, 20% were single unilateral ST, and one case presented double ST (8%) located bilaterally. The majority of ST (84%) were erupted conical-shaped. Conclusion: The study confirmed the exceptionally rare occurrence of NCHH in the anterior region of the mandible. Due to its interference with esthetics and function, the clinician should possess sufficient knowledge regarding NCHH diagnosis and management.
Cytodiagnosis of Visceral Leishmaniasis in Lymph Node Aspirate: A Rare Case Report
Authors: Agarwal Ruchi , Garg Prachi
Published: October 2022

Leishmaniasis is a parasitic disease caused by leishmania species. There are three main forms of the disease: Cutaneous, Mucocutaneous and Visceral Leishmaniasis (VL). VL with lymphadenitis is an uncommon presentation. Visceral leishmaniasis is usually diagnosed by identification of parasite Leishman Donovan (LD) bodies in bone marrow aspirates but cytological diagnosis of VL on lymph node aspirates has rarely been reported. This is a case report of a 37-year-old male presenting with multiple isolated cervical lymphadenopathy for three months. The lymphadenopathy was initially suspected to be tubercular in nature which is highly prevalent in India and lymphadenopathy is its common presenting feature, but on Fine Needle Aspiration Cytology (FNAC) of the node, multiple leishmania parasites were identified. Lymphadenopathy due to leishmaniasis is rare in India and most of the previous cases reported have association of leishmaniasis with Human Immunodeficiency Virus (HIV) infection. But this case is unusual as it is not associated with HIV infection. Thus, leishmaniasis should be included in the differential diagnosis of lymphadenopathy, especially in patients coming from endemic region. Cytology can be very helpful in such cases for early diagnosis and further management.
Variation in Body Weight and Biometric Traits of Exotic (Nicholas White) and Nigerian Locally Adapted Turkeys Reared in Humid Tropics
Authors: Utulu G. G. , Oguntade D. O. , Isidahomen C. E. , Ikhimioya I.
Published: October 2022

The performance of animal in a given environment differs between and within species, breeds and strains and genotypes, as a result of genetic variation. A total of 200 turkeys comprising 50 exotic (Nicholas white) and 50 each of Nigerian locally adapted turkeys (black, white and lavender) was used to investigate genetic variation in body weight and some biometric traits of exotic turkey and Nigerian locally adapted turkey at the Turkey Breeding unit of the Teaching and Research Farm of Ambrose Alli University, Ekpoma Edo State, Nigeria. The growth performance of the experimental birds was recorded biweekly throughout the period of the experiment. Genotype had significant effect (p<0.05) on body weight in all the weeks with exotic turkey consistently having higher (p<0.05) body weight throughout the experiment. The black plumage colour turkey performed better in body weight than the other two plumage colours of Nigerian locally adapted turkeys but was not significant (p>0.05). Similarly, exotic turkey has the highest (p<0.05) body length, body height, wing length, wing span and thigh length in most of the weeks of the experiment. Among the Nigerian locally adapted turkeys, black plumage turkey performed better (p<0.05) in most of the measured biometric traits than white and lavender plumage colour turkeys. The exotic turkey with higher body weight and biometric traits can be used to upgrade Nigerian locally adapted turkeys to obtain tropically adapted broiler turkey breed and also selection preferential should be given local black turkey for genetic improvement.
Evaluation of Anti-diabetic and Antioxidant Properties of Ethanol Leaf Extract of Jathropha tanjorensis
Authors: Chinonye Obioha Kennedy , Kalu Amah Akuma , Uche Elendu Melford , Barry Iheukwumere Chinedu
Published: October 2022

The aim of this study was to evaluate the anti-diabetic and antioxidant properties of ethanol leaf extract of Jathropha tanjorensis. Freshly harvested leaves of Jathropha tanjorensis were thoroughly processed into extract. Twenty five (25) adult male wistar rats were divided into five groups of five rats each. Group I was the normal control allowed unrestricted access to food and water only. Group II was the negative control and was induced with diabetes without treatment, Groups III and IV were diabetic rats administered with ethanol leaf extract of Jathropha tanjorensis, while Group V was diabetic rats administered with the standard drug. After treatment had been concluded, animals were sacrificed and blood and tissue obtained were analyzed using standard procedures. A significantly (P<0.05) high blood sugar level was reported for diabetic rats which however was significantly (P<0.05) reversed with oral administration of ethanol leaf extract of Jathropha tanjorensis in a dose dependent manner. The activity of the liver antioxidant enzymes was significantly (P<0.05) reduced in diabetic rats which however was significantly (P<0.05) increased following oral administration of Jathropha tanjorensis leaf extract in a dose dependent manner across treatment periods. In conclusion, the study unveils the antidiabetic and antioxidant potential of J. tanjorensis leaf.
Does Public Debt Determine Economic Growth; Evidence from Nigeria
Authors: Ogbodo Izuchukwu , Okafor Peters Sebastian Ogugua , Nwaobi Obinna Victor
Published: October 2022

The study examined the impact of public debt on economic growth of Nigeria with data captured from 1990-2020. Real Gross Domestic Product Growth Rate formed the dependent variable while external debt, domestic debt, exchange rate, inflation and interest rate are the independent variables. The study adopted Ex-post facto research design and also employed Ordinary Least Square analytical method. The findings of the study revealed that external debt had a positive and significant relationship with the real gross product growth rate, internal debt had a positive and significant relationship with the real gross product growth rate and that there was a uni-directional causality relationship between real gross product growth rate and external debt. The study therefore recommended that government should professionally manage the nations rising debt profile so as to avoid future debt trap, they should influence increase in local productivities and access to local financial facilities more and that they should also ensure stable exchange rate value of Naira.
Analysis of Sociocultural Factors for Schools Drop Out Among Girls in Tanzania: A Case Study of Junior Secondary School
Authors: Msafiri Mgambi , Lianyu Cai
Published: October 2022

School dropout among girls is a serious worldwide problem, especially in developing countries like Tanzania, which still faces the problem of girls dropping out despite international, national, and regional initiatives and steps to advance girls' rights. Like achieving gender equality and empowering all women and girls, as stated in SDG goal number 5. This study explores the sociocultural factors leading to high dropout among girls at junior secondary school in the mara region, Tanzania. A qualitative analysis was conducted to investigate the extent to which the social-cultural factors led to the high number of girls failing to complete their junior secondary studies in the Mara region by using a semi-structured interview and documentary review. With the semi-structured interview, the author interviewed fifteen parents and guardians, ten teachers (including school directors), and twenty dropout girls who participated in the study's discussions. This brought the overall number of research participants to 45. The interviewees, both women, and men were purposefully selected to be relevant to the current study. The study found that early marriage, female genital mutilation, household activities, social attitude against educating girls, and low levels of education among parents lead girls to drop out of school. It is suggested that the stakeholders should emphasize girls' education to avoid gender disparity. The government and NGOs should educate society and ensure that education in the Mara region should be prioritized for both boys and girls. To provide girls who are the victims of FGM with a safe place to run to, the government should prioritize creating rescue centers inside the districts with the help of local administration and other child activists.
A Case Report of an Advanced Stage Gastrointestinal Stromal Tumor Successfully Treated by Surgery and Imatinib
Authors: Meligy Ashraf Saad , ALakkad Ashraf , Almahameed Fadi Bassam , Chehal Aref
Published: October 2022

Background: The most prevalent gastrointestinal sarcoma is a gastrointestinal stromal tumor.It is frequently misdiagnosed due to its indolent symptoms, which only manifest at an advanced and potentially incurable stage.

Case Report: This case report is that ofa recent case of a GIST of gastric origin. Itdiscusses the case of a 56-year-old, non-smoking male with no comorbiditieswho presented to the emergency department with severe colicky intermittent adnominal pain that had occurred over the past three days, approximately three years ago. On September3, 2019, the patient underwent laparotomy in which a mass and related small bowel segment (the part of the omentum) was removed. Later, the pathology profile revealed a neoplasm of the small bowel-Ileum, Gastrointestinal stromal tumor (GIST) with a high-risk tumor of stage 4 with no recorded nodular involvement and no recorded metastasis pT4 pNxpMx but with clear margins. Moreover, the tumor markers KIT (CD117), CD34, and DOG1 (ANO1) were found to be positive. Ki67 was noted up to 35%. However, S-100 and SMA were found to be negative. On gross examination, the lesion's greatest dimension was 11 cm, and other dimensions were 9x6 cm. The tumor had a spindle-shaped morphology. On the basis of these laboratory findings and pathology profile, the patient's diagnosis was a Gastrointestinal Stromal tumor thatwas managed viasurgery. At that time, the patient was also prescribed Imatinib 400 mg. It has been three years since then, our patient is still alive, and no cancer recurrence has been reported yet.

Conclusion: This case report revealed that interventional radiology's early engagement with the surgical procedure was the cornerstone of our patient's effective treatment and should be investigated at different stages of the gastrointestinal tumor.
Quality of Service Reliability: A Study of Received Signal Quality in GSM Networks
Authors: Iloke Joel , Ekah Ukoette Jeremiah , Oduobuk Enobong Joseph , Ewona Igwe , Obi Emmanuel
Published: October 2022

Every radio frequency (RF) design, after its implantation, should be regularly evaluated. The kernel of this article is to evaluate the performance of four GSM networks, taking its received signal quality (RxQual) into consideration. A total of 10501, 10140, 10415 and 10690 RxQual measurements were obtained for MTN, 9mobile, Airtel and Globacom network. These generated data were subjected to statistical analysis in the form of bar charts, quality plots and calculations of measures of central tendency and dispersion. Result shows that 78.43%, 92.18%, 90.68% and 86.93% of the drive test route for MTN, 9mobile, Airtel and Globacom network had good signal quality and met with the Nigerian telecommunication regulatory benchmark of at least 4dB for RxQual. It is therefore deduced that in terms of RxQual, 9mobile was the best GSM network, followed by Airtel network, Globacom network and then MTN network. The result provided in this article will help mobile network operators to improve signal quality, ensure improved network coverage and increase network capacity in the future.
Sociodemographic and Clinical Risk Factors Associated with Mortality in Children with Acute Meningitis Admitted at Lubango Pediatric Hospital – Angola
Authors: Francisco Ketha , Benguela Gilberta , Chitungu Joana , Balogun Olukunmi Omobolanle , Tchicondingosse Lino
Published: October 2022

To reach the ambitious target of the UN Sustainable Development Goal (SDG), with countries aiming to end preventable death of newborn and under five children and reduce the mortality rate among children under 5 years to at least 25 per 1000 live birth, we need to understand the principles preventable causes and risk factors leading to child mortality. Among these preventable diseases, meningitis has one of the highest fatality rates and the potential to cause long term disability and devastating epidemics. This study is the first one in trying to identify the risk factors associated in mortality with meningitis in children admitted at luabango pediatric hospital.

We conducted a retrospective cross-sectional study to identify the sociodemographic and clinical risk factors associated with mortality in children admitted with the diagnosis of meningitis at lubango pediatric hospital, Angola. Following approval of the ethics committee at Lubango Pediatric Hospital, records of patients diagnosed with acute meningitis between 2020 and 2021 was extracted from infectious ward file record. Data was analyzed using SPSS 23.

20 (26.7%) of children admitted at lubango Pediatric hospital with the diagnosis of meningitis during the period of the study died.

Mother’s level of education ((P: 0.000), Vaccination status of the children (P:0.018) and vomiting (P: 0.007) were associated with mortality in a Bivariate analysis.

Lethality rate of children with the diagnosis of meningitis admitted at lubango Pediatric hospital during the period of the study was 26.7%.

mother’s level of education, Vaccination status of the children and vomiting were strongly associated with mortality.
Aerial Phytomass Production and Growth Performances of Five Common Tall Species in Andean Grasslands at Harvesting and Application of Natural Fertilizers
Authors: Yaranga R. M. , Maraví K. , Román M. Y. , Cáceres D. H. , Crispin A. V.
Published: October 2022

The objective of the research was to evaluate: aerial cover, canopy height and aerial phytomass production in five of the most common tall species in the area, in order to articulate it to a plant fiber production project. For the evaluation, 5 plots of 900 m2 were fenced, including 50 subplots of 32 m2, which were fertilized with cattle manure and phosphate rock. Monthly measurements were made from October 2020 to June 2021. At the end of the control, significant differences were observed for P = .01. Between plots they ranged from 1533±508 to 2909±192 cm2 in canopy cover (CC), from 36.9±0.89 to 38.3±2.31 cm in canopy height (CH) and 44±9.11 to 129±9.11 g DM/plant in Aerial Phytomass Production (AFP). Between species, they ranged from 2067±876 to 2975±200 cm2 in CC, from 33.2±3.86 to 40.3±1.24 cm in CH, and from 49.4±11.52 to 162.4±8.49g DM/plant in AFP. By fertilization effect the AFP varied as follows: those fertilized with phosphate rock reached 109.5±6.72 g DM/plant (14.7%), with cattle manure 88.8±6.72 g DM/plant (-5.3%), and finally the control plants with 93.5±15.03 g DM/plant, which means. A high canonical correlation was also observed between biological variables (canopy cover, canopy height, and dry matter production) and climatic variables (maximum temperature, minimum T. in °C, and rainfall in liters/m2). It was shown that tussock species respond quickly to cutting and natural fertilization has beneficial effects on biological indicators, despite the altitudinal difference between the plots and the particular species.
Effect of Solid Fermentation on Physicochemical and Microbial Compositions of Poultry Droppings for Biofertilizer
Authors: Ayantola K. J. , Imole P. O.
Published: October 2022

Aim: The study was carried out with the aim of determining what would be the effect of solid fermentation on the microbial loads and physicochemical compositions of poultry droppings in preparation of biofertilizer.

Place and Period: The study was carried out in the Department of Microbiology, Federal University of Technology Akure Ondo State in 2014.

Methodology: Solid fermentation was carried out on the poultry dung. Before the commencement of fermentation physicochemical and initial microbial load concentrations were determined. The microbial load of the poultry was evaluated for six days via plate count method. To isolate and identify the organisms associated with the dung, pour plate method was used. The following media were used for the isolation of microorganisms in poultry dung: Nutrient agar (NA); MaConkey agar (MCA); Mann Rogosa Shape (MRS0; Mannitol Salt agar (MSA), SIM agar, Moller Heaton agar (MHA), and Potato Dextrose agar (PDA). Identification of isolated bacteria was done tentatively based on microscopy, cultural and biochemical characteristics and according to the information of Bergey’s Manual of Bacteriological Identification.

Results: Eleven genera of bacteria and three species of fungi were isolated and identified in this study. Isolated bacteria are; Enterococcus feacalis, Corynebacterium xerosis, Staphylococcus aureus, Citrobacter freundii, Micrococcus reseus, Escherichia coli, Klebsiella spp, Proteus vulgaris, Staphylococcus captis and Streptococcus pyogen and fungi are Aspergillus fumigatus, Aspergillus niger and Aspergillus flavus respectively. Numerical values of physicochemical parameters before fermentation were on the lower values compared with the value during fermentation. Moisture content (29.52±0.06/75.45±0.08), Ash content (%) (3.43±0.42/9.93±013), PH (6.39/6.50), Crude protein (7.70±021/9.02±0.00), Total volatile Nitrogen (58.80/92.40). In the case of bacterial load, 1.79 x 104CFU/g was before the commencement of fermentation while the lowest load during fermentation was on fifth day with 5.1x102±0.00 CFU/g. However for the fungi load, the highest load recorded was 1.0x105 CFU/gg, on second day followed by 4.0x104 CFU/g, on third day of fermentation but on the fifth day fungi disappeared and reached zero.

Conclusion: the fermentation of poultry droppings increases the values of chemical constituents and decreases the microbial loads with time. Hence there is possibility of reducing the loads of pathogenic microorganisms in organic manure.
Formulation of Instant Atadjon (Mixed Tiger Nut and Rice) Flours Enriched with Legumes for Children of Weaning Age
Authors: Doué Ginette Gladys , Cissé Mariame , Zoué Thierry Lessoy , Mégnanou Rose-Monde
Published: October 2022

Aims: Formulate instant infant flours based on a mixture of Tigernut-rice enriched with legumes, maize and peanuts.

Study Design: Original research.

Place and Duration of Study: This study took place at the Laboratory of Biotechnology, Agriculture and Valorization of Biological Resources, Félix Houphouët-Boigny University between March and July 2022.

Methodology: The ingredient doses of the three instant flour recipes (F1, F2 and F3) were combined using the Pearson square according to the dietary recommendations. For this purpose, three compositions were prepared that achieved a protein content of 13%. These were compound flour F1 (47.10% tigernut-rice+42.90% voandzou+5 % maize + 5% groundnut paste), compound flour F2 (52.54% tigernut-rice+37.46% cowpea+5% maize+5% groundnut paste) and compound flour F3 (51.20% tigernut-rice+38.80% common bean+5% maize+5% groundnut paste). The nutritional content, the amino acid composition of these flours as well as the organoleptic properties of their porridges were determined according to standard methods.

Results: The results revealed that atadjon instant flours produced at 13% protein with maize, groundnut and mainly legumes voandzou (F1), cowpea (F2) and common bean(F3) are rich in complete proteins with all nine essential amino acids. However, the formulation based on F1 exhibited the highest content of these essential amino acids. Energy and carbohydrate values of the three formulations reached a satisfactory rate over 100% compared to the nutritional norms. The respective lipid (9.54; 6.18; 7.18%) and ash (1.87; 1.67; 1.67%) contents of the three instant atadjon flours were within the range of recommended values. Finally, the anti-nutritional factors are almost negligible since the fibre contents of 2.56% (F1), 3.45% (F2) and 3% (F3) are below the limits recommended by the standards, as are those of tannins and oxalates. the porridges prepared from these flours were appreciated by the tasters. However, the porridge prepared from atadjon flour F1 was the most appreciated for its colour, aroma and taste.

Conclusion: These good quality and nutritious intant flours, prepared from locally available and accessible ingredients, could therefore be recommended for infant feeding.
Influence of Micronutrients (Boron and Zinc) on Uptake and Availability of Nutrients
Authors: Bhat Tariq A. , Nabi Janeesa , Rather A. M. , Mushtaq F. , Chattoo M. A. , Mushtaq M. , Rashid Majid
Published: October 2022

An experiment was carried out SKUAST –K in two consecutive years (2016 and 2017) to study the effect of zinc and boron and their interaction on nutrient uptake in onion on nutrient uptake and soil properties of onion. In the experiment it was observed that sole zinc and boron levels, Z3 (7.500 kg Zn ha-1) and B3 (1.500 kg B ha-1) application proved superior in enhancing the uptake of all nutrients but exhibited lowest value in case of phosphorus uptake. It was further observed that interaction of zinc and boron proved superior to their sole applications in increasing uptake of nutrients. Treatment combination Z3B3 (7.500 kg Zn + 1.500 kg B ha-1) recorded significantly maximum value for uptake of nitrogen (113.93 kg ha-1), potassium (67.17 kg ha-1), boron (125.58 g ha-1) and zinc (184.01 g ha-1) but exhibited lowest value in case of phosphorus uptake. Sole application of zinc and boron and their combination exhibited a non-significant influence on soil pH, electric conductivity, organic carbon (%) and organic matter (%). Application of zinc (7.500 kg ha-1) and boron (1.500 kg ha-1) improved the availability of all nutrients except of phosphorus availability. Interactions of zinc and boron, proved synergistic in augmenting available nutrients except for phosphorus availability.
Prevalence of Sexually Transmitted Chlamydia trachomatis and Neisseria gonorrhoeae Infections in an Asymptomatic Population in Dakar, Senegal
Authors: Ndiaye Babacar , Seck Abdoulaye , Diop Abdou , Dieng Assane , Diallo Thierno Abdoulaye , Mahou Chantal , Dubrous Philippe
Published: October 2022

Introduction: Sexually transmitted infections (STIs) represent a major public health problem. Chlamydia trachomatis and Neisseria gonorrhoeae infections are often asymptomatic, thus leading to a high risk of transmission in subjects with risky behaviors. The objective of this study was to determine the prevalence of these 2 pathogens in an asymptomatic population.

Methodology: A retrospective, cross-sectional, descriptive study was conducted in the medical biology laboratory of the Pasteur Institute of Dakar over a period of 23 months in asymptomatic patients who were seen as part of a travel check-up. A first-draft urine sample was collected and tested for C. trachomatis and N. gonorrhoeae by molecular biology techniques. Data entry and statistical analysis were performed by Excel 2010 and SPSS 2.0 respectively.

Results: A total of 5012 patients were included and the overall prevalence of STIs related to these 2 pathogens was 3.8% (194/5012).

The prevalences of C. trachomatis and N. gonorrhoeae were 2.7% (137/5012) and 1.0% (55/5012), respectively. The age group most affected was [20-29 years] with 58.4% (80/137; p=0.0001) for C. trachomatis and 45.5% (25/55; p=0.471) for N. gonorrhoeae. Co-infection with these two germs was observed in 0.3% (18; p=0.001) of patients.

Conclusion: STIs with C. trachomatis and/or N. gonorrhoeae can be asymptomatic and continue the chain of transmission. Thus, for a better prevention of STIs due to these pathogens, it is important to screen, educate and sensitize the populations considered at risk.
Development of “care for skin integrity in the neonatal period”: documentation tool for skin conditions / Desenvolvimento do “cuidado com a integridade da pele neonatal”: instrumento para documentação das condições da pele
Authors: Nunes Grise Aline , Herdman T. Heather , Valentim Carmona Elenice , Baena de Moraes Lopes Maria Helena
Published: October 2022

Objetivo: Desenvolver instrumento para documentar as condições da pele e o manejo de feridas de pacientes neonatais. Método: Estudo metodológico realizado em etapas: desenvolvimento de instrumento para registro, com base na literatura; validação de conteúdo por comitê de especialistas e teste com 50 recém-nascidos com feridas. O coeficiente Kappa foi utilizado para avaliar itens qualitativos e o Coeficiente de Correlação Intraclasse (ICC) para quantitativos. Resultados: O conteúdo do Cuidado para a Integridade da Pele Neonatal (CIPNeo) foi validado por 9 especialistas. Conclusão: O conteúdo do CIPNeo foi validado. Apresentou confiabilidade satisfatória quando administrado por enfermeiras aos pacientes, sendo adequado para promover documentação sobre condições de pele e manejo de feridas. Os registros diários são essenciais para avaliação contínua quanto a prevenção, monitoramento e tratamento de feridas, assim como para fornecer suporte ao raciocínio clínico dos enfermeiros.
Cysteine biosynthesis in plants: isolation and functional identification of a cDNA encoding a serine acetyltransferase from Arabidopsis thaliana
Authors: Bogdanova Natascha , Bork Christiane , Hell Rüdiger
Published: July 2002

A cDNA encoding for serine acetyltransferase which catalyzes the committing step of cysteine biosynthesis has been cloned from Arabidopsis thaliana. The plant protein has a predicted molecular weight of 32.8 kDa and shows up to 43% of amino acid homology to bacterial serine acetyltransferases. It complements a serine acetyltransferase negative E. coli mutant and can be enzymatically determined in the heterologous host. The corresponding mRNA is predominantely expressed in light exposed tissue and represents one of at least two related genes.
Efficient transesterification of sucrose catalysed by the metalloprotease thermolysin in dimethylsulfoxide
Authors: Pedersen Ninfa Rangel , Halling Peter J , Pedersen Lars Haastrup , Wimmer Reinhard , Matthiesen Rune , Veltman Oene Robert
Published: July 2002

Thermolysin catalyses the formation of sucrose esters from sucrose and vinyl laurate in dimethylsulfoxide, with a specific activity of 53 nmol/min/mg and 2‐O‐lauroyl‐sucrose as the main product. Such transesterification reactions are normally observed only when the mechanism involves an acyl enzyme intermediate, as with lipases or serine proteases, and not with metalloproteases like thermolysin. A possible reason is the affinity of the active site of thermolysin for sugar moieties, as for the potent inhibitor phosphoramidon. The reaction is not catalysed by other proteins under the same conditions, and is inhibited by removal of the active site zinc.
Effects of isoproterenol on IL‐2 and cAMP production in peripheral T cells from asthmatic and non‐asthmatic subjects sensitive to Candida
Authors: Aihara Masayuki , Dobashi Kunio , Horie Takeo , Iizuka Kunihiko , Nakazawa Tsugio , Mori Masatomo
Published: July 2002

Summry— Immunity to Candida albicans (Candida) is characterized by a Th‐1 type pattern of reactivity. Candida is rarely a cause antigen for bronchial asthma. Beta agonists have been found to inhibit secretion of IL‐2 from T cells through intracellular cAMP elevation. We examined effects of isoproterenol (ISO) on Candida‐stimulated T cells. Peripheral T cells obtained from six Candida‐sensitive asthmatics, six Candida‐sensitive non‐asthmatic subjects, and six normal donors by Ficoll‐Hypaque gradient centrifugation and nylon‐wool column chromatography were incubated with Candida antigen or concanavalin A (Con A) in the absence or presence of ISO. Secretion of IL‐2 and intracellular accumulation of cAMP were assayed by ELISA. Con A induced secretion of IL‐2 in each of the three groups. Candida antigen induced IL‐2 secretion in the normal and the non‐asthmatic subjects, but not in the asthmatics. ISO, which reduced Con A‐induced secretion of IL‐2 in a dose‐dependent manner, had no effect on Candida‐induced secretion of IL‐2. Although ISO increased the intracellular concentration of cAMP in untreated and Con A‐treated T cells from all donors, cells from the normal and the non‐asthmatic subjects, but not from the asthmatics, that were co‐incubated with ISO and Candida had lower levels of cAMP than those treated with ISO alone. It is suggested that Candida antigen induces secretion of IL‐2 and reduces ISO‐inducible accumulation of cAMP in Candida‐responsive IL‐2 secreting cells, which may make Candida‐induced secretion of IL‐2 insensitive to ISO.
Glycoconjugate and adhesion molecule changes during the cell cycle in a human embryonic epithelial cell line
Authors: Fantin Anna Maria Bolognani , Franchini Antonella , Malgara Roberta , Rebecchi Barbara , Conti Anna Maria Fuhrman
Published: July 2002

The changes in the expression of glycoconjugates and adhesion molecules were studied by selective lectin binding and immunocytochemical reactions in a human embryonic epithelial cell line (EUE cells), synchronized in the cell cycle phases. The results can be summarized as follows: most of the tested lectins display a more diffuse binding for the cytoplasm in G1 than S and G2 phases; in the S and particularly in G2 phases the cytoplasm glycoconjugates are rearranged around the nucleus; cells in mitosis always show a strong binding towards all tested lectins. Cellular fibronectin and its receptor β1 integrin are well expressed in G1, but the strongest reaction is observed in the S phase. The immunoreactions for laminin and uvomorulin (L‐CAM) are poorly positive in all cell cycle phases. The immunocytochemical reaction for heparan sulfate is positive, with a stronger reaction in S and G2 than in G1; on the contrary a diffuse staining with the anti‐dermatan sulfate proteoglycan antibody appears unchanged during the cell cycle.
Regulation (Alteration) of Activity and Conformation of Sucrase by Coaggregation with Cellobiase in Culture Medium of Termitomyces clypeatus
Authors: Mukherjee Sumana , Basak Soumen , Khowala Suman
Published: July 2002

Extracellular sucrase (S) of Termitomyces clypeatus was aggregated with cellobiase (C) in culture filtrate and coaggregates of sucrase to cellobiase with different activity ratios (S/C) were obtained during purification. Specific activity of the enzyme decreased significantly, after purification of sucrase free from cellobiase. Purified sucrase was characterized as a glycoprotein of molar mass around 55kDa as indicated by SDS–PAGE and HPGPLC. Km and Vmax of the purified enzyme were determined as 34.48 mM and 13.3 U/mg, respectively, at optimum temperature (45 °C) and pH (5.0). Substrate affinity and reaction velocity of the purified enzyme, free from cellobiase, was lowered by approximately 3.5 and 55 times, respectively, than that of the enzyme obtained from culture filtrate. The instant regain of sucrase activity up to the extent of 41% was obtained on in vitro addition of cellobiase (free from sucrase) to the enzyme in incubation mixture. Conformation of the enzyme free from cellobiase appeared to be significantly different from that of the coaggregate, as analyzed by circular dichroic and light scattering spectroscopy. It was concluded that activity and conformation of sucrase is regulated (altered) by heteroaggregation with cellobiase in the fungus.
Extraction of Amino Acids Using an Immobilized Liquid Membrane
Authors: Adarkar J. A. , Sawant S. B. , Joshi J. B. , Pangarkar V. G.
Published: July 2002

A carrier‐mediated countertransport process for the extraction of amino acids is reported. The permeation of l‐Phe through a liquid membrane, constituted by a solution of ALIQUAT‐336 in toluene and supported by a hydrophobic microporous membrane, was studied. The best operating conditions were deducted by considering the effect of hydrodynamic factors, carrier concentration in the membrane phase, etc. The effect of impurities such as phosphates and tyrosine on the flux of Phe and selectivity of the carrier was evaluated.