bluuebunny/crossref_metadata_2025 huggingface dataset:
FORMULATION AND EVALUATION OF KALYANAKA KSHARA: AN AYURVEDIC COMPOUND FORMULATION
Authors: Anitha Suddala , Babu G , Vaibhav Charde , Prasad KMVD , Prasad PVNR
Published: May 2023

Background: Ayurveda utilises different forms of herbs in therapeutics. Kshara is one such form. The material destroys or cleans the excessive/morbid doshas (Ksharanat Kshananat va Kshara). They are considered anushastra’s (para-surgical instruments). Kshara’s (alkaline substances) are more suitable and can be used where shastra chikitsa (surgery) is contraindicated. Kshara (alkaline substances) is the best drug for internal and external use. Considering the quick action, lesser dose, and more comprehensive action, an attempt is made to formulate and standardise the product, as there is insufficient data regarding its standardisation. Objective: To formulate and standardise the Kalyanaka Kshara. Methods: All ingredients were taken per the reference Ashtanga Hridaya chikitsa sthana, Kalyanaka Kshara. All the Raw materials like plants, animals, and mineral drugs were collected from the local market of Jhansi, Uttar Pradesh. And by the sharava samputa (earthen pot) method, three different samples (KK1, KK2, and KK3) of Kalyanaka Kshara were prepared. Result: Physicochemical changes in each sample, organoleptic characters of the product yield were observed. The standard values of Kalyanaka Kshara are alkaline with pH 10.01, loss on drying (% w/w) 0.47, total ash value (% w/w) 55.5, acid insoluble ash value (% w/w) 0.93 water extractive value (% w/w) 62.55, alcohol extractive value (% w/w) 38.54. Conclusion: On behalf of each sample's pharmaceutical and physicochemical analysis, there are no considerable changes in any of the KK1, KK2, and KK3 samples, and encouraging results were observed. The developed SOP and physicochemical parameters can be adopted as pharmacopeial standards.
GAS CHROMATOGRAPHIC-MASS SPECTROMETRIC ANALYSIS OF K.G. 101 (KSHEERAGULOOCHI 101): AN AYURVEDIC PATENT PRODUCT
Authors: M Meenu , Narayanan Sibi
Published: May 2023

K.G.101 (Ksheeraguloochi 101) is an Ayurvedic patent product manufactured by Sitaram Ayurveda Private Ltd. Thrissur, Kerala. This is widely used by practitioners in the management of joint disorders. To explain this mechanism of action, the knowledge of biomedical compounds in the product is mandatory. The present study deals with the Gas chromatographic-mass spectrometric analysis of K.G.101 to explain its medicinal value. This type of study is the need of the hour for better scientific validation and a new approach to the treatment. The Gas chromatographic-mass spectrometric profile indicated the presence of nearly 39 molecules. Most compounds show anti-inflammatory potential, which explains their action in inflammatory joint disorders. The antioxidant property of the compounds explains their rejuvenating property. Some compounds show anti-cancerous activity also, which yet has to be explored.
HYDROALCOHOLIC EXTRACT OF ARTOCARPUS ALTILIS PROMOTES THE GLUCOSE UPTAKE: AN IN SILICO AND IN VITRO APPROACH
Authors: Patil Archana M. , Kaliyaperumal Sarvanan , Patil Mrityunjaya B. , Kumbhar Vrunda J.
Published: May 2023

Background: In various herbal formulations, Artocarpus altilis is used to manage diabetes and is listed as an insulin sensitiser. As a result, the current research attempted to identify the likely lead hits to promote glucose uptake using a computational approach, followed by an experimental assessment of a hydroalcoholic extract of the Artocarpus altilis Plant in yeast cells. Methods: The baker yeast was used for the in vitro assay for glucose uptake, while the in silico study involved retrieving phytoconstituents from public sources, predicting for likely targets of diabetes, and then predicting for likely side effects and ADMET profile. In addition, PyRx 0.8's Autodock Vina predicted each ligand's affinity for binding to the glucose transporter. 13 phytoconstituents from Artocarpus altilis were found to have antidiabetic properties. At 500 g/mL, the extract demonstrated the highest glucose uptake in yeast cells. Network pharmacology identified 2, 4, 5', 7'-tetrahydroxyflavanone and 2, 4, 5', 7'-tetrahydroxyflavane phytoconstituents from Artocarpus altilis as specific targets that were modulated in the MAPK signalling pathway, PI3-Akt signalling pathway, and insulin signalling pathway. These targets included INSR, AKT1, PTPN, and IGFR1. Conclusion: Here, the in vitro and in silico methods used in the present study illustrated the potential role of phytoconstituents from Artocarpus altilis in promoting glucose uptake.
The Effect of Firm Size, Auditor Switching and Public Accounting Firm Reputation on Audit Delay with Audit Risk as Moderation for Manufacturing Companies
Authors: Ruwanti Gemi , Asyikin Jumirin , Ramaraya Tri , Noor Fauzian , Boedi Soelistijono , Maladi Muhammad
Published: May 2023

This study aims to analyze and obtain empirical evidence regarding audit risk as moderating the effect of firm size, auditor switching, and public accounting firm reputation on audit delay. The data collection*employed purposive sampling technique which was carried out at manufacturing companies on the Indonesia Stock Exchange in*2018 to 2020. Thus obtaining 89 manufacturing companies as samples. Moreover, in analyzing the data, Moderated Regression Analysis (MRA) with an interaction test approach was used. Furthermore, the results of the study showed that audit risk weakened the effect of firm size on audit delay. Meanwhile, audit risk did not moderate the effect of auditor switching and public accounting firm reputation on audit delay.
Morphometric Features of Cells of Cervical Intraepithelial Neoplasia Using Computer Aided Image Analysis
Authors: Olaniyi Olaofe Olaejirinde , Morakinyo Akinyemi Hezekiah , Oluwole Komolafe Akinwumi
Published: May 2023

Aim: Our goal is to evaluate and compare the different cell morphometric parameters in the various categories of cervical intraepithelial neoplasia (CIN).

Study Design: We conducted a cross-sectional study of all cervical intraepithelial neoplasia identified in some areas of biopsies of cervical carcinomas.

Place and Duration of Study: The study was in the department of histopathology of LAUTECH Teaching Hospital, Osogbo from January 2006 to December 2015.

Materials and Methods: The histologic slides produced were scanned using CS2 APERIO digital slide scanner with standard settings. The scanned slides were then viewed using Qu Path-0.3.2 software. All areas of cervical intraepithelial neoplasia were selected. The perimeter, area, maximum caliper, circularity, eccentricity, and the various measures of hematoxylin optic densities (OD) of the nucleus of the cells were measured. The cytoplasmic morphometric measurements and the nuclear-cell ratio were then estimated.

Results: Two cases of CIN 1, one case of CIN 2 and one case of CIN 3 were seen in the background of the eighty-seven cases of cervical carcinomas seen during the study period. A total of 5,935 cells were in the annotated regions with cervical intraepithelial neoplasia. The cells in CIN 1 area are 3,828, CIN 2 area has 1183 cells and CIN 3 areas has 924 cells. Cells of CIN 3 had higher average nuclei hematoxylin optic density (OD), nuclei hematoxylin OD standard deviation and maximum hematoxylin OD than cells of CIN 2 and CIN 1. Cells of CIN 1 have higher average cell area, cell perimeter, cell circularity and mean cytoplasm eosin OD compared to cells of CIN 2 and 3.

Conclusion: Computer-aided image analysis using Qu Path software can be very instrumental in differentiating the various categories of cervical intraepithelial neoplasia especially in fragmented biopsies.
The Correlation between QRS Dispersion and Coronary Artery Disease Severity in Patients with Non ST Elevation Myocardial Infraction
Authors: Boudhar Zainab , Nehame Sana , El-Jamili Mohammed , El-Karimi Saloua , El-Hattaoui Mustapha
Published: May 2023

Non ST elevation myocardial infarction (NSTEMI) has been the subject of numerous studies. Risk stratification is a fundamental element for the management of NSTEMI; therefore, several scores have been established in this direction, particularly prognostic markers derived from the ECG.

Aims: The aim of our study is to correlate the dispersion of the QRS with the severity of coronary lesions assessed by the GENSINI score in patients admitted for NSTEMI at the University Hospital of Marrakech.

Methods: A retrospective study was conducted in the cardiology department of Mohammed VI university hospital of Marrakech from January 01, 2022 to March 31, 2022. Data was derived from the hospitalization register, including 30 patients (16 women and 14 men). Age ranged from 56 to 74 years with an average of 64.6 ± 9.3. Data was analyzed by SPSS, the level of significance set at p <0.05.

Results: We found, in our study, a highly significant positive correlation between QRS dispersion (considered important if >20 ms) and admission heart rate (p=0.003) as well as the level of ultrasensitive troponins (p=0.003). There is also a very significant correlation between QRS dispersion and corrected QT interval (p=0.005), Moreover, we concluded that in patients admitted for NSTEMI, the greater the dispersion of the QRS, the higher the score of GENSINI (p<0.0001).

Conclusion: The dispersion of the QRS is a simple marker on the ECG that can have a predictive value in different clinical contexts, particularly in acute ischemic heart disease. Further studies are needed, however, to validate its usefulness in routine practice.
Impact of Pulsing and Holding Solutions on Vase Life of Melaleuca bracteata F. Muell Foliage
Authors: Babu K. Raja , Palai S. K. , Beura S. , Tripathy P. , Samanta P.
Published: May 2023

The experiment was conducted during the year 2019-21 at Horticulture Research Station, OUAT, Bhubaneswar laid out in factorial CRD design to check the vase life of Melaleuca bracteata foliage by using distilled water (control) and different pulsing, holding solutions and 6 modules, which contains different spacing, pit size, FYM, basal fertilizer dose, water soluble fertilizers and growth regulator (BAP). Pulsing solution containing Sucrose (2%) + Al2(SO4)3 (1000 ppm) (9.89 days) resulted long vase life of foliage followed by solution containing Sucrose (2%) + BA (50 ppm) (9.10 days) in module VI. Whereas holding solution containing Sodium Benzoate (150 ppm) (9.10 days) showed long vase life of foliage followed by Sodium Benzoate (100ppm) (9.02 days) in module VI.
Effect of Moisture Content and Particle Size on Characteristics of Fuel Pellets Using Flat Die Type Pelleting Machine
Authors: Jagtap Abolee , Kalbande Surendra
Published: May 2023

Fuel pellets are a popular form of biomass energy due to their high energy density, ease of handling, and reduced emissions. The quality of fuel pellets is influenced by various factors, including the moisture content and particle size of the raw materials (Soybean straw and cotton stalk) used during the pelletization process. In this study, the effect of moisture content and particle size on the characteristics of fuel pellets produced using a flat die type pelleting machine was investigated. Different moisture content levels (ranging from 20 to 30%) and particle sizes (ranging from 4 to 8 mm) were used to pelletize a biomass feedstock. The pellet characteristics, including pellet durability, bulk density and water resistance and energy consumption were evaluated.  The results showed that both moisture content and particle size significantly influenced the characteristics of the fuel pellets as well as energy consumption. Based on the findings, an optimal moisture content of 25% and particle size of 6 mm were determined for producing fuel pellets with desirable characteristics and low energy consumption was required using the flat die type pelleting machine. These results can provide valuable insights for biomass pellet producers and researchers in optimizing the pelletization process to achieve high-quality fuel pellets with improved properties.
Management of Capsule Borer Conogethes punctiferalis (Guenee) on Castor Ricinus communis L. Using Some Plants Oil
Authors: Kirankumar R. , Sannappa B. , Reddy Vijayachandra
Published: May 2023

The insecticides were tested under field conditions on the basis of percentage of capsule bore Conogethes punctiferalis (Guenee) infestation noticed under field condition. The capsule borer C. punctiferalis (Guenee) damage goes on decreasing among the chemical and plant based insecticidal treatments at first and second week after spraying. Among the eight treatments, the lowest capsule borer damage/plant recorded by T5 Mahua oil 2% with 43.55% reduction over control followed by T6 neem oil 2% recorded 36.05% reduction over control recorded during 1st week after spray. The percentage of capsule borer C. punctiferalis (Guenee) damage per plant was highest recorded by T1 treatment it was mainly due to, this treatment did not receive any insecticidal spray either chemical or plant based insecticides throughout the experimental period. Same trend was noticed after 2nd week after spray. During 2nd week after spray highest percent of reduction over control recorded by T6 neem oil 2% recorded 80.27% reduction over control followed by T7 pongamia oil 2% recorded 79.09% reduction over control. Lowest percentage of castor capsule borer C. punctiferalis (Guenee) per plant recorded by T6 neem oil 2%, T7 pongamia oil 2% and T5 mahua oil 2% which were statistically at par with throughout the observation. The T6 neem oil 2% and T7 pongamia oil 2% recorded as best treatments over rest of the treatments. The grain yield in the treatment significantly highest grain yield @3730.00 kg and 3627.63 kg recorded by T6 Neem oil 2% and T7 Pongamia oil 2% followed by T5 Mahuva oil recorded yield @ 3283.30kg. However, the chemical treatments viz., T3 Profenophos 50 EC @0.03% and T4 quinolphos 25 EC @ 0.05% recorded yield @ 2956.66 and 2936.00 kg/ha both at par with each other. Whereas untreated control recorded the lowest yield @2426.03 kg/ha.
Convergence of Baskakov Durrmeyer Operators in the Reverse Order of q-Analogue
Authors: Garg Sangeeta
Published: May 2023

This research paper is an introduction to a new type of analogue named as  -analogue for well-known Baskakov Durrmeyer operators. This new type of analogue is considered as reverse order of -analogue. In this paper, we establish the direct approximation theorem, a weighted approximation theorem followed by the estimations of the rate of convergence of these new type of operators for functions of polynomial growth on the interval.
Role of Suprachoroidal Anti-VEGF Injections in Recalcitrant Serous Pigment Epithelium Detachment
Authors: Datta Ditsha , Khan Perwez , Khan Lubna , Singh Ankita
Published: May 2023

Purpose: Retinal pigment epithelial detachments (PEDs) are characterized by a separation between the RPE and the innermost aspect of Bruch's membrane. Many chorioretinal diseases can lead to pigment epithelial detachment of which the most common is age-related macular degeneration; but a significant number of PEDs are idiopathic in etiology. PEDs can be classified as drusenoid, serous, vascularized, or fibrovascular type.

Currently, serous PED has not shown much response to treatment, so no specific treatment guidelines are established. Whereas vascularized PEDs, have several treatment options such as intravitreal anti-Vascular endothelial growth factor (VEGF) therapy, laser photocoagulation, photodynamic therapy (PDT) and intravitreal steroids. Hence, the need of the hour is to formulate a treatment strategy for serous PED.

Methods: We report an original study of thirty patients who were diagnosed with serous pigment epithelial detachment on Spectral-domain optical coherence tomography and fundus fluorescence angiography. All the patients presented to our outpatient department with the chief complaint of diminution of vision, central/paracentralscotoma and metamorphopsia. All of them underwent treatment with suprachoroidal anti-VEGF (bevacizumab).The patients were followed 8 weeks.

Results: BCVA and Amsler grid assessment was recorded on the 3rd day,1st week, 2nd week, 4th week, 6th week, and 8th week. Post-injection SD-OCT macular scan was performed on the 6thweek. Functional improvement (BCVA) was reported by all patients. All the patients had reduced size and height of PED in SD-OCT.

Conclusion: Thus, our result indicates that suprachoroidalbevacizumab is an efficacious treatment for serous PED. It can be hypothesized that as degenerative changes in bruch membrane due to metabolite deposit plays a key role in development of PED; injecting the anti VEGF drug in the suprachoroida space adjacent to the choroid has a superior effect.
Cotton Harvests and Economic Growth: A Comprehensive Study of Tajikistan's Industry
Authors: Yunusov Bezhan , Guiyu Zhao
Published: May 2023

The cotton industry has played a significant role in Tajikistan's economic and social development. However, it has also faced various challenges, such as poor infrastructure, limited access to finance and markets, and outdated technology. To promote its sustainable development, this study employs a mixed-methods approach to identify the industry's challenges and opportunities and propose growth strategies. The research findings suggest that the cotton industry in Tajikistan has significant potential for growth, including favorable climate conditions for cotton production and a growing global demand for cotton products. However, inadequate infrastructure, outdated technology, and limited access to finance and markets remain significant challenges. To address these challenges, the study proposes several strategies, including investment in infrastructure, technology modernization, governance improvement, and market access. The study also highlights the importance of ensuring fair wages, providing access to healthcare and education, and addressing issues such as child labor and gender inequality to improve the living standards and working conditions of cotton farmers and workers in the industry. In conclusion, this research provides valuable insights into the challenges and opportunities facing the cotton industry in Tajikistan and its impact on the country's economy, environment, and social development. The study's recommendations can inform policymakers, industry stakeholders, and development practitioners in promoting sustainable development in Tajikistan.
ANALISIS PRODUKTIVITAS PEKERJAAN PASANGAN BATA RINGAN MENGGUNAKAN METHOD PRODUCTIVITY DELAY MODEL (MPDM) PADA PROYEK APARTEMEN DI SURABAYA
Authors: Jefferson William , Andi Andi
Published: May 2023

Salah satu kunci keberhasilan sebuah proyek konstruksi terletak pada ketepatan waktunya. Karena itu, setiap proyek diharapkan memiliki tingkat produktivitas yang tinggi agar proyek tidak mengalami keterlambatan. Pekerjaan pasangan batu bata juga merupakan salah satu aspek penting, karena pabila pekerjaan tersebut mengalami keterlambatan, maka pekerjaan yang lainnya akan secara otomatis ikut tertunda. Namun pada kenyataannya, seringkali produktivitas yang diharapkan tidak dapat selalu direalisasikan, alhasil sebuah proyek menjadi terlambat. Maka dari itu, tujuan dari penelitian ini adalah mengetahui produktivitas idealnya, serta mengetahui faktor keterlambatan yang paling berpengaruh. Pengamatan berlangsung selama 25 hari kerja, dan jumlah data yang didapatkan adalah sebanyak 270. Dari hasil analisis, didapatkan bahwa rata-rata produktivitas yang terjadi di lapangan adalah sebesar 47,3 m2/hari. Sedangkan untuk produktivitas idealnya adalah sebesar 52,7 m2/hari. Faktor keterlambatan yang berpengaruh terhadap pekerjaan pasangan bata ringan adalah faktor pekerja dan faktor material.
ANALISA FAKTOR COST OVERRUNS DENGAN METODE INTERPRETIVE STRUCTURAL MODELLING PADA BEBERAPA PROYEK KONSTRUKSI DI INDONESIA
Authors: Limantoro Calvin , Andi Andi , Rahardjo Jani
Published: May 2023

Dalam industri konstruksi, pembengkakan biaya (cost overruns) merupakan permasalahan yang umum terjadi. Sedangkan, permasalahan cost overruns menjadi salah satu kunci utama dalam kesuksesan suatu proyek. Oleh karena itu, permasalahan cost overruns sangat perlu untuk diperhatikan. Diperlukannya analisa terhadap faktor-faktor penyebab adanya cost overruns. Penelitian ini bertujuan untuk mengetahui faktor paling dominan yang menyebabkan cost overruns pada proyek konstruksi di Indonesia dan hubungan antar faktor penyebab pembengkakan biaya. Metode yang digunakan untuk mengidentifikasi dan menganalisis interaksi antar berbagai faktor pada penelitian ini adalah Interpretive Structural Modeling (ISM). ISM merupakan metode yang dapat menggambarkan struktur sistem yang kompleks melalui grafik maupun kata-kata. Pada penelitian ini menggunakan metode kuesioner dengan lima belas faktor yang menjadi penyebab cost overruns. Responden pada penelitian ini berjumlah delapan ahli yang telah berpengalaman pada bidang konstruksi. Hasil penelitian menunjukkan bahwa akar masalah dari cost overruns pada proyek konstruksi adalah keterbatasan sumber daya manusia.
PENGARUH HUBUNGAN GAYA KEPEMIMPINAN TRANSFORMASIONAL DAN TRANSAKSIONAL TERHADAP MOTIVASI KERJA KARYAWAN PERUSAHAAN JASA KONSTRUKSI DI KOTA AMBON MENGGUNAKAN METODE PARTIAL LEAST SQUARE-STRUCTURAL EQUATION MODELING
Authors: Tandelilin Rikson Kurniawan , Widyadana Gede
Published: May 2023

Penelitian ini dilakukan untuk mengetahui pengaruh dari variabel gaya kepemimpinan transformasional dan gaya kepemimpinan transaksional terhadap motivasi kerja karyawan di perusahaan konstruksi kota Ambon. Sampel yang digunakan adalah karyawan dari perusahaan yang terdaftar sebagai anggota ASPEKINDO kota Ambon tahun 2022. Teknik analisis data yang digunakan adalah analisis deskriptif dan multivariat dengan PLS-SEM. Hasil penelitian pada perusahan konstruksi di kota Ambon, gaya kepemimpinan transformasional berpengaruh positif dan signifikan terhadap motivasi kerja karyawan. Sedangkan gaya kepemimpinan transaksional berpengaruh negatif dan signifikan terhadap motivasi kerja karyawan. Pada gaya kepemimpinan transformasional, ketika semakin tinggi persepsi terhadap gaya kepemimpinan atasan maka semakin tinggi motivasi kerja dari karyawan. Sedangkan untuk gaya kepemimpinan transaksional, mendapatkan kesimpulan berbeda yaitu ketika semakin tinggi persepsi gaya kepemimpinan transaksional maka semakin rendah motivasi kerja dari karyawan.
As contribuições metodológicas de Mao Zedong: notas para uma crítica do Estado soviético
Authors: Alvares de Farias João Guilherme
Published: May 2023

Nosso objetivo é propor uma abordagem metodológica que possibilite uma compreensão alternativa à tese staliniana do cerco capitalista como justificação para o fortalecimento do Estado soviético. Nossa hipótese é que a leitura de Mao Zedong sobre o materialismo histórico e dialético nos permite traçar um caminho mais rigoroso para a compreensão desse fenômeno. Para tanto, confrontamos a tese staliniana com os pressupostos teóricos dos clássicos do marxismo, apresentamos as contribuições de Mao e formulamos algumas notas para futuras pesquisas. Esperamos estabelecer com algum grau de clareza o problema teórico que envolve a tese staliniana e a pertinência da abordagem metodológica aqui apresentada.
Inconsciente e adoecimento psíquico na psicologia soviética [Flávia Gonçalves da Silva]
Authors: Santos Andressa Carolina Viana dos
Published: May 2023

Resenha do livro Inconsciente e adoecimento psíquico na psicologia soviética. de Flávia Gonçalves da Silva.
Neoliberalismo e desenvolvimento da concepção de mundo: uma leitura a partir da Psicologia Histórico-Cultural
Authors: Pereira Juliano Baltazar
Published: May 2023

O trabalho debate o desenvolvimento do psiquismo e da concepção de mundo no período hegemonizado pelo neoliberalismo e sua variante ideológica, o social-liberalismo. Em um primeiro momento, realiza-se uma discussão teórica sobre o conceito de social-liberalismo. No segundo, ocorre a exposição da Psicologia Histórico-Cultural enquanto compreensão de sujeito. No terceiro e último momento, examina-se uma letra do subgênero musical funk ostentação, utilizando a obra como objeto de análise da concepção de mundo de uma parcela da juventude no início da década de 2010. Conclui-se que o social-liberalismo reforça uma concepção de mundo voltada para o individualismo e a defesa da ordem.
Contribuições da psicologia histórico-cultural para a educação escolar brasileira: o experimento formativo
Authors: Portilho de Lima Cárita , Campos Herculano Ricardo
Published: May 2023

O presente ensaio teórico tem como objetivo refletir sobre as contribuições que a psicologia histórico-cultural pode oferecer à educação escolar brasileira desde suas elaborações no campo do método e de um de seus desdobramentos: o experimento formativo. Em síntese, defendemos que esse debate contribui para uma compreensão científica sobre as relações entre ensino, estudo, aprendizagem e desenvolvimento de modo a enfrentar a reprodução do fracasso escolar e questionar a falsa polêmica entre uma educação escolar que ensine conteúdos científicos versus uma educação que capacite para a vida. Por fim, entendemos que essa discussão também oferece ferramentas potentes ao enfrentamento dos efeitos das políticas neoliberais no campo da educação escolar brasileira.
A imagem e o processo gerador subjetivo da realidade objetiva: elementos psicológicos e pedagógicos da formação humana à luz da Teoria Histórico-Cultural
Authors: Vieira Saulo , Aguiar Wanda Maria Junqueira de , Ferreira Isabel Cristina Fernandes , Lima Ana Ignez Belém
Published: May 2023

Esse artigo consiste em um ensaio acerca do processo histórico de construção teórica que envolve o conceito de subjetividade desde os primeiros trabalhos de Vigotski até a extensão de seu legado por meio de Gonzalez-Rey. Aponta a categoria Dimensão Subjetiva da Realidade como elemento analítico central da unidade  teórico-metodológica existente entre a Psicologia Histórico-Cultural e a Pedagogia Histórico-Crítica, mais especificamente como condição para reflexão sobre/para uma educação emancipadora para a classe trabalhadora.
Os limites epistemológicos da articulação entre psicanálise e marxismo: considerações em defesa de uma psicologia materialista histórico-dialética
Authors: Bulhões Larissa , Magalhães da Silva Márcio
Published: May 2023

No presente texto buscamos refletir sobre as articulações entre marxismo e psicanálise, comuns na atualidade, apontando os fundamentos do pensamento marxiano que revelam os limites e a insuficiência da psicanálise para a compreensão da subjetividade humana. Concluímos que a psicanálise, ainda que possa ter contribuído historicamente para o pensamento crítico do campo marxista, deve ser superada em prol do desenvolvimento de uma teoria psicológica alternativa, alicerçada no materialismo histórico-dialético, dando sequência ao trabalho iniciado por L. S. Vigotski nas décadas de 1920-1930, no contexto revolucionário da União das Repúblicas Socialistas Soviéticas (URSS).
O papel da divisão sociossexual do trabalho na constituição de subjetividades gendradas
Authors: Martins dos Santos Souza Terezinha
Published: May 2023

Desde a economia política dos trabalhadores, objetiva-se conhecer como o capital recorre ao sistema sexo/gênero para se perpetuar como modo de organizar a vida, expresso na organização patriarcal da família. Analisam-se as relações entre divisão sociossexual do trabalho, linguagem e família no engendrar das desigualdades de gênero. Para a construção de um mundo humanamente emancipado, defende-se a abolição da divisão sexual do trabalho, pilar da divisão social do trabalho. Que a organização do trabalho seja determinada pela necessidade social do sujeito coletivo e pelo desejo/capacidade dos sujeitos singulares.
A situação social do desenvolvimento infantil
Authors: Bozhovich Lydia , Marília Daefiol Herrero Gomes Tradutora
Published: May 2023

Neste texto, Bozhovich discute dois conceitos propostos por Vigotski: o conceito psicológico de idade e a situação social do desenvolvimento. Ambos são apresentados como mecanismos que constituem a força motriz do desenvolvimento juntamente com as necessidades básicas das crianças. A segunda parte do capítulo aborda a concepção de Bozhovich a respeito do conceito de perejivanie. 
Esta tradução foi realizada com base na seguinte publicação do texto “The social situation of child development” de Lídia Bozhovich publicado no Journal of Russian & East European Psychology. A versão deste mesmo trabalho em espanhol foi utilizada para fins de comparação e para sanar algumas questões de tradução.
Clinical experience in the use of 3D printing as a rapid replacement of traditional radiation therapy immobilization materials
Authors: Ehler Eric D.
Published: May 2023

Purpose

Patient positioning and immobilization devices are commonly employed in radiation therapy. Unfortunately, cases can arise where the devices need to be reconstructed or improved. This work describes clinical processes to use a planning CT, to design and 3D print immobilization devices for reproducible patient positioning within a clinically feasible time frame when traditional methods can no longer be used or are insufficient.

Materials/Methods

Three clinical cases required rapid 3D printing of an immobilization device mid‐treatment due to the following: (1) a lost headrest cushion, (2) needed improvement in lumbar spine positioning, and (3) a partially deflated vacuum immobilization mattress.

Results

In the three cases, the 3D printed immobilization devices were clinically implemented successfully; two of the devices were fully designed and printed in 1 day. The 3D printed immobilization devices achieved a positioning accuracy sufficient to avoid the necessity to repeat the simulation and planning process.

Conclusion

If traditional immobilization devices fail or are misplaced, it is feasible to have a 3D printed replacement within the time span of 1 day. The design and fabrication methods, as well as the experiences gained, are described in detail to assist clinicians to implement 3D printing for similar situations.
How Does Exercise, With and Without Diet, Improve Pain and Function in Knee Osteoarthritis? A Secondary Analysis of a Randomized Controlled Trial Exploring Potential Mediators of Effects
Authors: Lawford Belinda J. , Hinman Rana S. , McManus Fiona , Lamb Karen E. , Egerton Thorlene , Keating Catherine , Brown Courtney , Oliver Kathryn , Bennell Kim L.
Published: May 2023

Objective

To explore the mediators of effects of two 6‐month telehealth‐delivered exercise programs, including exercise with and without weight‐loss diet, on pain and function improvements in knee osteoarthritis (OA).

Methods

Secondary analysis of 345 participants from a 3‐arm randomized controlled trial of exercise (Exercise program) and exercise plus diet (Diet + Exercise program) versus information (Control program) was conducted. Outcomes were changes in pain (11‐point numeric rating scale) and function (Western Ontario and McMaster Universities Osteoarthritis Index [score range 0–68]) at 12 months. Potential mediators were change at 6 months in attitudes toward self‐management, fear of movement, arthritis self‐efficacy, weight, physical activity, and willingness for knee surgery. For the Diet + Exercise program versus the Exercise program, only change in weight was evaluated.

Results

Possible mediators of the Exercise program versus the Control program included reduced fear of movement (accounting for –1.11 units [95% confidence interval (95% CI) –2.15, –0.07] improvement in function) and increased arthritis self‐efficacy (–0.40 units [95% CI –0.75, –0.06] reduction in pain, –1.66 units [95% CI –3.04, –0.28] improvement in function). The Diet + Exercise program versus the Control program mediators included reduced fear of movement (–1.13 units [95% CI –2.17, –0.08] improvement in function), increased arthritis self‐efficacy (–0.77 units [95% CI –1.26, –0.28] reduction in pain, –5.15 units [95% CI –7.34, –2.96] improvement in function), and weight loss (–1.20 units [95% CI –1.73, –0.68] reduction in pain, –5.79 units [95% CI –7.96, –3.63] improvement in function). Weight loss mediated the Diet + Exercise program versus the Exercise program (–0.89 units [95% CI –1.31, –0.47] reduction in pain, –4.02 units [95% CI –5.77, –2.26] improvement in function).

Conclusion

Increased arthritis self‐efficacy, reduced fear of movement, and weight loss may partially mediate telehealth‐delivered exercise program effects, with and without diet, on pain and/or function in knee OA. Weight loss may partially mediate the effect of diet and exercise compared to exercise alone.
Engaging Multistakeholder Perspectives to Identify Patient‐Centered Research Priorities Regarding Vaccine Uptake Among Adults With Autoimmune Conditions
Authors: Venkatachalam Shilpa , Gavigan Kelly , Banerjee Shubhasree , Gordon Jennifer , Emrich Lisa , Sullivan Hope , Blazer Ashira , Banbury Brittany , Weaver Kimberly N. , Stradford Laura , Dronadula Vandana , Degrassi Angela , Merkel Peter A. , Shaw Dianne G. , Larsen Kalen , Curtis Jeffrey R. , McBurney Robert N. , Kappelman Michael D. , George Michael D. , Nowell W. Benjamin
Published: May 2023

Objective

The study objective was to prioritize topics for future patient‐centered research to increase uptake of common vaccines, such as for pneumococcal pneumonia, influenza, herpes zoster, human papillomavirus, and severe acute respiratory syndrome coronavirus 2, among adults living with autoimmune conditions.

Methods

A steering committee (SC) was formed that included clinicians, patients, patient advocates, and researchers associated with rheumatic diseases (psoriatic arthritis, rheumatoid arthritis, vasculitis), inflammatory bowel disease, and multiple sclerosis. Through a scoping review and discussions, SC members identified research topics regarding vaccine uptake and/or hesitancy for prioritization. A larger multistakeholder alliance that included patients and patient advocates, clinicians, researchers, policy makers, regulators, and vaccine manufacturers conducted a modified Delphi exercise online with three rating rounds and one ranking round. Frequency analysis and comparisons across stakeholder groups were conducted. A weighted ranking score was generated for each item in the ranking round for final prioritization.

Results

Through the Delphi process, 33 research topics were identified, of which 13 topics were rated as critical by more than 70% of all stakeholders (n = 31). The two highest ranked critical topics per the full stakeholder group were “How well a vaccine works for adults with autoimmune conditions” and “How beliefs about vaccine safety affect vaccine uptake.”

Conclusion

A multistakeholder group identified key topics as critically important priorities for future research to decrease vaccine hesitancy and improve uptake of vaccines for adults with autoimmune conditions.
Ionic Thermoelectric Properties of Reconstructed Lamellar Vanadium Pentoxide Membranes
Authors: Gogoi Raktim , Madeshwaran Harshan , Ghosh Arnab , Green Yoav , Raidongia Kalyan
Published: May 2023

In recent years, the application of ionic thermoelectric (TE) materials to convert low‐grade waste heat into electricity has become a subject of intense scientific research. However, most of the efforts are focused on organic polyelectrolytes or ionic‐liquids embedded in polymeric gels. Here, for the first time, it is demonstrated that nanofluidic membranes of reconstructed layered materials like vanadium pentoxide (V2O5) exhibit excellent ionic‐TE characteristics. The high Seebeck coefficient (S = 14.5 ± 0.5 mV K‐1) of the V2O5 membrane (VO‐M) is attributed to temperature gradient‐induced unidirectional transport of protons through the percolated network of 2D nanofluidic channels. The TE characteristics of VO‐M show nearly 80% improvement (S = 26.3 ± 0.7 mV K‐1) upon functionalizing its percolated network with ionic polymers like poly(4‐styrenesulfonic acid) (PSS). Further, unlike organic polymer‐based TE systems, VO‐M not only sustains exposure to high temperatures (≈200 °C, 5 min) but also protects the PSS molecules intercalated into its interlayer space. Moreover, V2O5‐based TE materials can self‐repair any damage to their physical structure with the help of a tiny water droplet. Thus, nanofluidic membranes of reconstructed layered materials like VO‐Ms demonstrate vast robustness and great ionic‐TE performance, which can provide a novel platform for scientific studies and futuristic applications.
Functional Textiles with Smart Properties: Their Fabrications and Sustainable Applications
Authors: Zhang Yabin , Xia Xiaohu , Ma Kaikai , Xia Gang , Wu Maoqi , Cheung Yuk Ha , Yu Hui , Zou Bingsuo , Zhang Xiangwu , Farha Omar K. , Xin John H.
Published: May 2023

Benefiting from inherent lightweight, flexibility, and good adaptability to human body, functional textiles are attracting tremendous attention to cope with wearable issues in sustainable applications around human beings. In this feature article, a comprehensive and thoughtful review is proposed regarding research activities of functional textiles with smart properties. Specifically, a brief exposition of highlighting the significance and rising demands of novel textiles throughout the human society is begun. Next, a systematic review is provided about the fabrication of functional textiles from 1D spinning, 2D modification, and 3D construction, their diverse functionality as well as sustainable applications, showing a clear picture of evolved textiles to the readers. How to engineer the compositions, structures, and properties of functional textiles is elaborated to achieve different smart properties. All these tunable, upgraded, and versatile properties make the developed textiles well suited for extensive applications ranging from environmental monitoring or freshwater access to personal protection and wearable power supply. Finally, a simple summary and critical analysis is drawn, with emphasis on the insight into remaining challenges and future directions. With worldwide efforts, advance and breakthrough in textile functionalization expounded in this review will promote the revolution of smart textiles for intelligence era.
Electrical Property Enhancement in Orientation‐Modulated Perovskite La‐Doped SrTiO3 Thermoelectric Thin Films
Authors: Zheng Yunpeng , Chen Hetian , Zhou Zhifang , Yang Yueyang , Zou Mingchu , Zhang Wenyu , Wei Bin , Cai Jinghan , Lan Jin‐Le , Yi Di , Nan Ce‐Wen , Lin Yuan‐Hua
Published: May 2023

Thermoelectric oxide thin films are promising in chip cooling. The issues on the orientation of thin films are essential as they are related to the structures, morphologies, and thermoelectric properties. In this regard, the orientation modulation is conducted on La‐doped SrTiO3 thin films on (LaAlO3)0.3(Sr2TaAlO6)0.7 (LSAT) single crystal substrates. Layer‐by‐layer growth mode is found in (001)‐ and (110)‐ oriented thin films, resulting in few grain boundaries (GBs). In (111)‐oriented films, island growth mode leads to columnar grain boundaries that build up potential barriers for electrons to be strongly scattered and filtered, suppressing electron mobility and increasing effective mass. In addition, the GBs serve as oxygen vacancy diffusion paths when annealing, causing increased carrier concentration and lattice contraction. The weighted mobility of 71.9 cm2 V−1 s−1 and electrical conductivity of ≈600 S cm−1 are realized in the (001)‐oriented film at room temperature. Ultimately, outstanding power factor values of ≈569 µW m−1 K−2 (room temperature) and ≈791 µW m−1 K−2 (573 K) are successfully achieved, outperforming those in polycrystalline ceramics and (111)‐oriented films. This study systematically investigates the influence of grain boundaries and orientations on SrTiO3‐based thermoelectric films, which lays a solid foundation for improving thermoelectric performance in other oxide thin films.
Self‐Folding Graphene‐Based Interface for Brain‐Like Modular 3D Tissue
Authors: Sakai Koji , Teshima Tetsuhiko F. , Goto Toichiro , Nakashima Hiroshi , Yamaguchi Masumi
Published: May 2023

Electrophysiology of 3D neuronal cultures is of rapidly growing importance for revealing cellular communications associated with neurodevelopment and neurological diseases in their brain‐like 3D environment. Despite that the brain also exhibits an inherent modular architecture that is essential for cortical processing, it remains challenging to interface a modular network consisting of multiple 3D neuronal tissues. Here, a self‐folding graphene‐based electrode array is proposed that enables to reconstruct modular 3D neuronal tissue and investigate firing dynamics among moduli. A graphene‐sandwiched parylene‐C film self‐folds into a cylindrical structure within which living cells can be encapsulated. Culture of encapsulated cells inside the folded graphene enables to spontaneously construct 3D cell aggregates and ensure firm contact between the graphene surface and encapsulated cells. As the inner graphene surface can be utilized as an electrode, the reliable cell–electrode contact allows for long‐term electrical recording from multiple 3D aggregates. Additionally, the modular network consisting of multiple 3D aggregates exhibits richer firing patterns than a conventional homogenous 2D network, which demonstrates that the approach enables measurements of firing dynamics in complex 3D neuronal networks. The deformable graphene electrode will be a powerful platform for investigating complex cellular communications in brain‐like 3D cultures.
Atomic and Electronic Reconstruction in Defective 0D Molybdenum Carbide Heterostructure for Regulating Lower‐Frequency Microwaves
Authors: Yuan Mingyue , Lv Hualiang , Cheng Hanwen , Zhao Biao , Chen Guanyu , Zhang Jincang , Che Renchao
Published: May 2023

0D nanomaterials with high efficiency of atom utilization possess extraordinary tunability over bulk materials. Precise reconstruction of atoms in a 0D nanoparticle toward tuning of crystalline phases and defects is highly desirable but remains a grand challenge. In this study, a crystallization rate‐controlled strategy is reported to achieve controllable reconstruction of atoms in situ, which inducts a series of monodisperse 0D molybdenum carbide nanoparticles (MoxC NP) that anchor on a carbon matrix with adjustable crystalline phases and atom vacancies. Aberration‐corrected transmission electron microscopy, electron paramagnetic resonance technique, density functional theory calculation, and electron holography jointly reveal the atomic reconstruction process and confirm its remarkable effects of optimizing the local electronic states and enhancing the heterointerface interactions. As a result, the optimized MoC/Mo2C heterostructure on the carbon matrix is shown to enable the promoted dielectric response and generate more than 90% absorption of lower‐frequency microwaves (the current 5th‐generation communication band). The control of atomic reconstruction may provide an effective pathway for unlocking tunable dielectric properties of 0D nanomaterials toward various technological applications.
Single‐Step 3D Printing of Micro‐Optics with Adjustable Refractive Index by Ultrafast Laser Nanolithography
Authors: Gonzalez‐Hernandez D. , Sanchez‐Padilla B. , Gailevičius D. , Thodika S. Chandran , Juodkazis S. , Brasselet E. , Malinauskas M.
Published: May 2023

Laser exposure defines voxel's dimensions as essential building blocks in direct write 3D nanolithography. However, the exposure conditions not only influence the size of the produced features but also their optical properties. This empowers the realization of an adjustable refractive index out of single material by varying the writing strategy while preserving laser 3D nanolithography's flexibility in geometry and high resolution. Here, the refractive index for the 450–1600 nm spectral range of the micro‐optics out of SZ2080 hybrid polymer is systematically studied by applying ray and wave optics approaches followed by optical resolution analysis. It reveals the exact value of the laser‐printed components instead of the determination assessed by other techniques measuring thin films or bulky volumes of the investigated substance. The studied micro‐lenses are of below 100 µm in dimensions and a clear distinction in their performance on low and high exposure doses is found by analyzing it in all different approaches and validating using different lithography setups. Findings reveal the complexity of the refractive index of the 3D micro‐optics which is influenced by the material density and morphology. A route for freedom in 3D printing shape and refractive index can be realized by the technological optimization of delicate exposure control in ultrafast laser nanolithography.
Near‐Infrared I/II Nanophosphors with Cr3+/Ni2+ Energy Transfer for Bioimaging
Authors: Satpathy Aishwarya , Huang Wen‐Tse , Chan Ming‐Hsien , Su Ting‐Yi , Kamiński Mikołaj , Majewska Natalia , Mahlik Sebastian , Leniec Grzegorz , Kaczmarek Sławomir M. , Hsiao Michael , Liu Ru‐Shi
Published: May 2023

In the biomedical field, the use of fluorescence imaging in the second near‐infrared (NIR‐II) region is growing rapidly because it imparts the advantages of reduced autofluorescence and low photon scattering. The advantage of reduced scattering is that it increases penetration depth in vivo and improves imaging clarity. Herein, this work uses mesoporous silica, a biocompatible template that can be easily modified, functionalized, and loaded with drugs for use in several bioapplications. The ZnGa2O4 spinel oxide system is integrated into mesoporous silica and different concentrations of Cr3+ and Ni2+ are loaded in octahedral sites to obtain the highest emission intensity in the NIR‐II region at 1285 nm via energy transfer from Cr3+ to Ni2+. Given that only a few nanophosphor systems with emission in the NIR‐II region are available, this work attempts to establish emission in the NIR‐II and NIR‐I regions to obtain images in vivo with an increased penetration depth to 5 mm and improved clarity for bioimaging purposes. This system will open the door for biomedical research on other NIR‐II nanophosphors.
Composition‐Dependent Ferroelectricity of LuFeO3 Orthoferrite Thin Films
Authors: Cho Eunsoo , Klyukin Konstantin , Su Tingyu , Kaczmarek Allison , Ross Caroline A.
Published: May 2023

This work characterizes the structural, magnetic, and ferroelectric properties of epitaxial LuFeO3 orthoferrite thin films with different Lu/Fe ratios. LuFeO3 thin films are grown by pulsed laser deposition on SrTiO3 substrates with Lu/Fe ratio ranging from 0.6 to 1.5. LuFeO3 is antiferromagnetic with a weak canted moment perpendicular to the film plane. Piezoresponse force microscopy imaging and switching spectroscopy reveal room temperature ferroelectricity in Lu‐rich and Fe‐rich films, whereas the stoichiometric film shows little polarization. Ferroelectricity in Lu‐rich films is present for a range of deposition conditions and crystallographic orientations. Positive‐up‐negative‐down ferroelectric measurements on a Lu‐rich film yield ≈13 µC cm−2 of switchable polarization, although the film also shows electrical leakage. The ferroelectric response is attributed to antisite defects analogous to that of Y‐rich YFeO3, yielding multiferroicity via defect engineering in a rare earth orthoferrite.