bluuebunny/crossref_metadata_2025 huggingface dataset:
LEITURA E ESCRITA: A INTERVENÇÃO PEDAGÓGICA COMO MEIO EFETIVO NA ALFABETIZAÇÃO DE CRIANÇAS
Authors: Costa Francisco Klebio e , Coutinho Diógenes José Gusmão
Published: January 2025

O desafio de alfabetizar segue sendo perseguido e tido como um tarefa crucial aos que  se interessam pelo tema, tais como familiares de crianças em idade escolar, estudiosos, gestores públicos e docentes, sobretudo estes últimos que se dedicam a lecionar em séries iniciais do Ensino Fundamental. Cada docente tem a sua metodologia, a sua didática de como levar adiante a empreitada cotidiana de mediar a construção e a aquisição da leitura e da escrita que, às vezes, é exitosa. De algum modo, o assunto toca ao tecido social, exigindo reflexões que contribuam na compreensão e superação definitiva desse problema que se arrasta, sem que se vislumbre uma solução próxima.Este artigo buscou na obra dos teóricos Soares(2009),  Ferreiro (2011,2013, 2014, 2015), Grossi (1990), Antunes (2003) um espaço de diálogo para que este trabalho fosse possível e fundamentado, uma vez que suas teorias transitam fartamente no bojo do tema da escrita e da leitura, seus desafios e possibilidades, mas, sobretudo, suas teorias oferecem ocasião de reflexão e revisão de práticas docentes, muitas das quais arraigadas em métodos comprovadamente anacrônicos, que já não respondem às exigências da escola atual, inserida no âmbito das transformações tecnológicas, de costumes e, em especial,  no que se refere à escrita e à leitura, suas demandas que crescem diuturnamente.
TRAUMA CONTUNDENTE E ALTERAÇÕES CARDÍACAS: O PAPEL DA COMMOTIO CORDIS NA MORTE SÚBITA
Authors: Andrade Vitória Letícia Lima de , Moura Giovanna Kailany Machado de Oliveira , Saraiva Sarah Hemmyly Honorato , Lima Lucas Lucena de , Ramalho Wostenildo Crispim
Published: January 2025

Esse artigo buscou compreender como o Commotio Cordis (CC), síndrome rara e fatal, implica para o desenvolvimento de morte súbita. O presente estudo consiste em uma revisão bibliográfica integrativa, com abordagem de pesquisa quantitativa baseada em uma questão norteadora, com o universo amostral de todos os artigos disponíveis nas bases de dados Medical Publisher (PUBMED), Biblioteca Virtual em Saúde (BVS) e Literatura Latino-americana e do Caribe em Ciências da Saúde (LILACS), delimitando para os 5 últimos anos de publicação (2015-2025). Foi analisado que ao acontecer o impacto não perfurante e contundente sobre o precórdio de um paciente, no momento da fase de despolarização ventricular ou no pico da onda T da repolarização, quando o miocárdio está mais vulnerável, é desenvolvida o CC. O impacto resulta em um aumento súbito da pressão intracavitária do ventrículo esquerdo, ativando canais iônicos sensíveis ao estiramento, levando ao desenvolvimento de arritmias fatais. Dessa forma, é de suma importância a identificação precoce do evento, iniciação de Ressuscitação Cardiopulmonar (RCP) e defibrilação precoce, para que minimize drasticamente a mortalidade.
رصد وتقييم لسدود حفظ التربة والمياه لبعض أودية وسفوح الجبل الأخضر
Authors: Murad, M. Aburas  , Mohammed, A. Mahjoub  , Mohammed S. Yousef
Published: January 2025

تعاني السفوح الجنوبية للجبل الأخضر من ظروف مناخية شبه جافة ساهمت مع النشاط البشري غير المستدام في تدهور الأراضي، ووضع القطاع الزراعي والرعوي تحت ظروف إنتاجية صعبة. تم في هذه الدراسة متابعة وتقييم حالة عدد من السدود التعويقية الحجرية ببعض منحدرات جنوب مراوة بالجبل الأخضر من حيث كفاءة الموقع والأداء والاستمرارية في حفظ التربة والمياه. ولتحقيق اهداف الدراسة تم تقدير بعض خصائص التربة والانحدار والخصائص الموروفومترية بتلك المنحدرات. كما تم رصد نشاط انجراف التربة ببعض روافد وادي درنة القادمة من جنوب القبة حيث لا يتوفر العدد الكافي من السدود التعويقية، كما تم الاستعانة ببعض القياسات الميدانية والخرائط الرقمية وتحديد نوع التربة ورصد مظاهر تدهورها. وجدت الدراسة ان الروافد القادمة من جنوب القبة لتغذية وادي درنة قد اتصفت بنشاط مكثف لعمليات الإنجراف، كما أظهرت الملاحظات والقياسات الميدانية كميات كبيرة جدا من الرواسب التي انتقلت الى الوادي وساهمت في تقليل السعة التخزينية لسد بومنصور قبل انهياره. لعبت الترب الجافة بالمنطقة والمتدهورة في صفاتها الفيزيائية، دورا اساسيا في قابليتها للانجراف مع غياب اي نظام متكامل ومستدام لإدارة الاراضي يستطيع مواجهة ظروف الهشاشة البيئية والتغيرات المناخية المتوقعة. سجلت الدراسة كذلك، العديد من مظاهر الفشل وضعف الكفاءة للعديد من السدود التعويقية جنوب مراوة مثل التباعد غير المنتظم ما بين السدود وتوسع التعرية الاخدودية والانهيارات الجزئية وغياب الصيانة الدورية. عدم تطبيق خطة إدارة متكاملة ومستدامة تشتمل توزيعا كافيا للسدود التعويقية يراعي الاختلافات المكانية في الخصائص المورفومترية والهيدرولوجية، وظروف الترب الجافة والنشاط البشري والتذبذب المناخي، وأثره في سلوك الجريان السطحي وتكرار حوادث السيول الجارفة بتلك الاودية والروافد، كانت سببا رئيسيا لهذا الخلل. معالجة هذا القصور سيسهم بدون شك في الحد من اضرار الفيضانات والاستفادة من حصاد المياه وتحقيق تنمية مكانية ملموسة.
The Role of Knowledge Management and Cause Related Marketing towards Sustainability to promote Societal Marketing Concept
Authors: Qadeer Rooma , Rafi Nosheen
Published: January 2025

This study aims to categorize and validate the histories and results of environmental sustainability in green manufacturing in Pakistan, with a primary focus on small and medium-sized businesses (SMEs). This study investigates how knowledge management processes (KMPs), more especially knowledge application, dissemination, and acquisition, function as precursors to environmental sustainability. Partial least squares structural equation modeling (PLS-SEM) was used to examine data gathered from 450 SMEs via an online survey. This study investigates how, in the context of green manufacturing, CRM, knowledge management, and environmental sustainability are related. Important results show that: (1) CRM significantly affects environmental sustainability, and (2) CRM moderates the eco-friendly relationship between KM and environmental sustainability. The study's conclusions have significant ramifications for researchers, managers, and policymakers who want to comprehend the dynamics of environmental sustainability in Pakistani SMEs engaged in green manufacturing. Limitations and future research directions are also covered in this work.
ASSESSMENT OF SCHOOL PRINCIPAL’S STRATEGIES TO ENHANCING PHYSICAL SECURITY MEASURES: A CASE STUDY OF SECONDARY SCHOOLS SITUATED IN SOUTH EAST STATES, NIGERIA
Authors: Emeruwa H. I. , Ogbonna R. N. O. , Afianmagbon B. E.
Published: January 2025

The study examined Secondary School Principals’ Strategies and Physical Security Measures in South East States, Nigeria. A total of 1500 teachers were sampled in 272 secondary schools. The technique used in the selection was the disproportionate random sampling technique. The school principal’s strategies and physical security questionnaire (SPSAPSQ) was the instrument used for data collection. It was validated and the reliability test yielded 0.79 Cronbach Alpha coefficients. Mean statistics were used to answer the two research questions while analysis of variance (ANOVA) was used to test the two hypotheses at a 0.05 level of significance. Results indicate a large concurrence of teachers that the provision of surveillance-communication gadgets and deployment of security barriers by principals impacted positively on enhancing security measures in schools. For enhancing school safety, planning and adequate security measures such as provision of first aid kits, fumigating the environments, covering of gutters, ensuring the perimeter of the school is fenced, provision of lighting materials, installation of CCTV to cover blind spots, liaising with community, security agencies and stakeholders for supports.
Status Keberlanjutan Agribisnis Aren di Kabupaten Garut
Authors: Yuslam Fauzan Muhammad Irfan , Awaliyah Fitri
Published: January 2025

Keberlanjutan agribisnis aren menjadi topik strategis di Kabupaten Garut karena perannya yang signifikan dalam mendukung perekonomian lokal serta menjaga keseimbangan lingkungan. Penelitian ini bertujuan untuk mengevaluasi status keberlanjutan agribisnis aren melalui analisis aspek ekologi, ekonomi, dan sosial. Metode penelitian menggunakan pendekatan kuantitatif dengan analisis statistik deskriptif berdasarkan data primer dan sekunder. Responden penelitian terdiri dari 30 petani aren yang dipilih secara purposive sampling berdasarkan kriteria tertentu. Hasil penelitian menunjukkan bahwa aspek ekologi memiliki tingkat keberlanjutan baik, didukung oleh penggunaan pupuk organik, rendahnya penggunaan pestisida, serta daya serap tanah yang optimal. Aspek ekonomi juga berada pada tingkatan keberlanjutan yang cukup baik karena aren memberikan kontribusi signifikan terhadap pendapatan petani, meskipun terdapat kendala dalam akses permodalan dan pemasaran. Di sisi lain, aspek sosial masih memerlukan perhatian lebih karena lemahnya partisipasi petani dalam pengelolaan, minimnya dukungan kelembagaan, dan kurangnya informasi terkait keberlanjutan agribisnis. Secara keseluruhan, agribisnis aren di Kabupaten Garut memiliki potensi keberlanjutan yang positif, tetapi untuk mencapainya diperlukan langkah-langkah strategis seperti penguatan kelembagaan untuk pendampingan petani, peningkatan akses pasar agar produk aren lebih kompetitif, pengembangan inovasi teknologi yang berkelanjutan, serta mendorong keterlibatan aktif petani dalam pengelolaan agribisnis. Langkah terpadu ini diharapkan dapat mendukung keberlanjutan agribisnis aren secara menyeluruh, optimal, holistik, dan berkesinambungan.
Nilai Tambah, Keuntungan, Gula, ANALISIS NILAI TAMBAH PRODUK HASIL OLAHAN AREN
Authors: Roudotul Janah Nabila , Muhammad Nu'man Adinasa
Published: January 2025

Tujuan dari penelitian ini yaitu untuk menganalisis nilai tambah dari pengolahan produk berbasis aren, yaitu gula merah, sapu ijuk, dan gula semut, dengan mengkaji aspek biaya produksi, tenaga kerja, dan keuntungan yang diperoleh dari setiap jenis pengolahan. Metode yang digunakan dalam penentuan lokasi yaitu dengan cara purposive sampling. Analisis data para penelitian menggunakan analisis data primer dan sekunder, data primer yang dihasilkan dari proses wawancara kepada para pengolah aren dan data sekunder yang diperoleh dari instalasi terkait seperti BPS dan Dinas Pertanian. Teknik dalam pengambilan sample dalam penelitian ini menggunakan purposive sampling dengan kriteria sample yaitu para petani yang melakuka pengolahan aren. Penelitian ini menggunakan metode rasio nilai tambah, yang mengukur perbandingan antara biaya bahan baku, output yang dihasilkan, serta kontribusi tenaga kerja terhadap produksi. Hasil penelitian menunjukkan bahwa pengolahan gula semut menghasilkan nilai tambah yang paling tinggi, dengan rasio keuntungan yang mencapai 80%, diikuti oleh gula merah dengan marjin keuntungan 83%, dan sapu ijuk dengan marjin keuntungan 59%. Biaya bahan baku untuk gula semut lebih tinggi, tetapi produk ini memiliki nilai jual yang lebih tinggi pula, meskipun marjin keuntungan lebih rendah. Sebaliknya, pengolahan gula merah lebih menguntungkan karena biaya bahan baku yang lebih rendah dengan proses produksi yang tinggi. Produksi sapu ijuk, menggunakan bahan baku yang murah, memerlukan keterampilan manual yang lebih banyak, sehingga menghasilkan keuntungan yang lebih rendah.
Síndrome Platipneia–Ortodeoxia, uma Causa Rara de Dispneia
Authors: Ribeiro Joana Freitas , Gorgulho Cátia , Lopes Débora , Matos Ana , França Luís , Catorze Nuno
Published: January 2025

A Síndrome Platipneia-Ortodeoxia (SPO) é uma condição rara e subdiagnosticada, caracterizada por dispneia e hipoxia em ortostatismo e na posição sentada, que se resolvem em decúbito dorsal. Os autores relatam o caso de uma mulher de 79 anos, com dispneia de agravamento progressivo há três dias. Na urgência, foi constatada dispneia e dessaturação com necessidade crescente de oxigenoterapia ao se levantar. Exames laboratoriais, eletrocardiograma e tomografia computadorizada do tórax não apresentaram alterações que justificassem o quadro. O ecocardiograma transtorácico e transesofágico revelaram um shunt direita-esquerda devido a um volumoso aneurisma do septo interatrial, tratado com oclusão por prótese Atriasept – CARDIA™. O procedimento resultou em resolução imediata dos sintomas. O diagnóstico da SPO é essencialmente clínico. O cateterismo cardíaco é considerado o padrão-ouro para o diagnóstico, mas o ecocardiograma desempenha um papel fundamental na identificação da etiologia subjacente. O tratamento é dependente da causa, e essa condição está associada a um bom prognóstico.
Systemic Risk Management for Occupational Hazards in the Human Service Professions
Authors: Floyd A.E.
Published: January 2025

The human service professions have long been known to be associated with elevated risk for occupational stress syndromes, including burnout and compassion fatigue. This paper conceptualizes such syndromes as the result of exposure to occupational hazards that are endemic to human service work. Identifying moral injury (MI) and secondary traumatic stress (STS) as hazards that exist across human service professions, this paper then reviews resilience research from many human service professions. Synthesizing scholarly traditions that have typically remained separate, it identifies organization-level practices that may mitigate the risk of exposure to occupational hazards and build psychological resilience in the work force. It also identifies gaps in the resilience literature, topics that are not fully explained by existing models, and avenues for future research.
Synthesis of 2-(4-Methyl-Phenoxymethyl) Benzoic Acid; Cresol and its Metal Coordinate Complexes
Authors: Waheed Saima , Nazakat Fakiha , Abbas Nasir , Nadeem Munaza , Ghafoor Sidra , Shabir Ghulam Shabir , Saeed Aamer
Published: January 2025

A series of phenoxymethylbenzoic acid derivatives were synthesized by reacting p-cresol with phthalide. The resulting phenoxymethyl benzoic acid was converted into corresponding acid chloride by reacting with cyanuric chloride. These phenoxymethyl benzoyl chlorides were then reacted with various aminobenzenesulfonamides and synthesize d new sulfonamide derivatives. The targeted sulfonamides were subjected to structural characterization by contemporary spectroscopic techniques like UV-visible and FT-IR. The presence of a peak at 3400/cm confirmed the existence of amide functionality, and furthermore , the broad peak at1250/cm showed that the sulfone group is present in the molecule.
Industry hurdles and technology adoption on the internet of things (IoT) at industry 4.0
Authors: Fakhar-Ur-Rehman  , Rahman Rasool  , Mubbashar Hussain  , Alishba Fatima  , Ridah Naushad  , Muhammad Waseem Iqbal  , Misbah Noor
Published: January 2025

The deployment of "Industry 4.0" technologies is trendy and the manufacturing sector is currently facing challenges in both industrialized and developing economies which are examined in the study. After systematically assessing the work and consulting with an industry expert, barriers are identified and examined using a "Grey Decision-Making Trial and Evaluation Laboratory" (DEMATEL) method. The absence of digital strategy is the biggest obstacle in developed and emerging economies. The influencing hurdles were found to indicate that government norms and regulations might be improved to make Industry 4.0 technologies more accessible to emerging nations. For these technologies to be adopted in industrialized nations a technological infrastructure is required. The deployment of “Industry 4.0” in both industrialized and developing economies should be first examined. This article emphasizes how the lack of unified national policies on "Industry 4.0" in poor nations makes it harder for technical innovation to spread which may inhibit businesses from fully embracing the "Industry 4.0" revolution. To successfully deploy Industry 4.0 across the industrial sector decision makers and practitioners may find it useful to address the hurdles identified by the study's findings.
Improved Lightweight Image Encryption and Decryption for Medical IoT Devices Using 6D Chaotic Maps with XOR Diffusion, Permutation and Substitution
Authors: Abdul Muhammed Rasheed
Published: January 2025

This research introduces a lightweight image encryption framework specifically designed for medical IoT devices, utilising a 6D chaotic map in conjunction with XOR diffusion, pixel permutation, and an optional substitution layer. The methodology utilises the intrinsic randomness, ergodicity, and sensitivity of high-dimensional chaotic systems to achieve robust encryption and secure transmission of sensitive medical images, including X-rays, MRIs, and ECGs. Comprehensive evaluations indicate that the framework effectively disrupts spatial coherence, attaining nearly zero pixel correlation and high entropy (~8), while maintaining computational efficiency suitable for resource-constrained IoT environments. The encryption scheme demonstrates significant sensitivity to input variations, with an average NPCR of 99.6% and a UACI surpassing 33%, highlighting its robustness against differential and statistical attacks. The comparative analysis of traditional and lower-dimensional chaotic encryption methods reveals that the proposed algorithm offers a superior balance between cryptographic security and performance. The findings demonstrate that the proposed system is a feasible solution for real-time, secure image processing in medical IoT applications. Future research will investigate adaptive parameter tuning and the integration of machine learning to improve encryption efficiency and robustness.
Evaluating the Impact of Green Governance on Sustainability Performance in Nigeria's Energy Sector: A Stakeholder Perspective
Authors: Usman Bashir Mikail , Johl Satirenjit Kaur , Khan Parvez Alam
Published: January 2025

This paper considers the concept of green governance as a reactionary effort or response to the environmental consequences arising from the exploitative human interaction with the elements of nature. The present industrial revolution has increased the level of production, heightened companies' profit margins, and resulted in environmental hazards. Additionally, the chain of manufacturing to consumption has resulted in environmental degradation, ozone depletion, and the destruction of traditional livelihoods for most global economies. Through empirical evidence from relevant literature, this study finds that Nigeria’s energy sector accounts for 90% of the total export volume and is the major contributor to environmental degradation; hence, the implementation of green governance and sustainability performance should be championed by the energy firms. To this end, the stakeholder theory is used to analyze a model of synergy between stakeholders to implement green governance. Nonetheless, green governance practices among these energy firms are very low compared to other developed countries such as the United Kingdom, Russia, China, and Germany. This paper concludes by providing viable future research discourses that would add to the body of knowledge on green governance practices in Nigeria.
The Relationship between Entrepreneurial Attitude, Entrepreneurial Education, and Entrepreneurial Intentions of Millennial College Students, Entrepreneurial Self-Efficacy as a Mediator
Authors: Tian Feng , Tan Helen Sui-Hong , Yang Yi-Ting
Published: January 2025

Due to the development and reform of the social economy, entrepreneurship has become a career choice for many college graduates. The study aims to examine the factors that influence entrepreneurial intentions among millennial college students in Jinan, Shandong Province, China. A total of 405 valid questionnaires were collected as the sample, and the data were analyzed using SPSS version 27 to assess correlations and effects. In addition to the primary data, secondary sources, including research articles and online resources, were consulted for further insights. The results indicated that entrepreneurial attitude, entrepreneurial education, and entrepreneurial self-efficacy have a positive impact on entrepreneurial intention, with entrepreneurial self-efficacy being the most significant factor. The value of the research lies in providing insights for educational institutions, policymakers, and support organizations to foster entrepreneurship among millennials. Future research should consider larger samples, diverse data collection methods such as offline research and interviews, and longitudinal studies for deeper understanding of and guidance for entrepreneurial development.
Dietary supplementation of composite feed additive reduces enteric methane production and enhances feed efficiency, milk production and immunity in Murrah buffalo (Bubalus bubalis)
Authors: Dey Avijit , Paul Shyam S. , Dahiya Satbir S. , Balhara Ashok K. , Andonissamy Jerome , Punia Balbir S. , Chanu Yendrembam M.
Published: January 2025

Buffalo plays a fundamental role in the livelihood of peo ple of Asian countries by providing milk, meat, draught power, and dung. Asia is home to more than 90% of the world’s buffalo population, out of which South Asian countries harbor about 78% of buffaloes. India ranks first in the world’s total milk production, where about 50% of milk is contributed by 108.9 million total buffaloes, 57% of the global buffalo population. At the same time, buffaloes are one of the country’s most significant contributors to greenhouse gases. Therefore, the objective of the present study was to develop a rumen-balanced composite feed additive (RESMI) for reducing enteric methane production and improving health and production performances in buffaloes. The present research involved a series of in vitro, in sacco, and in vivo experiments in growing (n=24) and milking buffaloes (n=18). The feed supplement was developed at the institute, composed of an ideal combination of methane inhibitors, alternate hydrogen sinks, and some rumen-stimulating agents (Indian Patent Grant No. 388717 dated 08.02.2022) and its efficacy examined through a series of in vitro experiments. A completely randomized design was used to analyze the experimental data. Supplementation of RESMI (@ 2.5% of feed intake.) was found to reduce methane emission (p<0.05) by reducing the number of methanogenic archaea in the rumen and promoting the growth of alternate hydrogen utilizers like sulfate-reducing bacteria. The feed additive stimulated the rumen ecosystem by increasing microbial fibrolytic activity. It thus increased (p<0.05) fiber digestion, reducing the rate of ammonia production in the rumen with concomitant improvement in feed utilization and performance of buffaloes, resulting in an increase in the growth rate by 10%, feed conversion efficiency by 15% and milk production by 10.4%. The results revealed increased digestibility of nutrients, especially crude fiber, with decreased (p<0.05) methane concentration in the exhaled air of lactating buffaloes. The health status regarding cell-mediated and humoral immune response was also enhanced (p<0.05) in supplemented buffaloes. The feed supplement RESMI significantly reduced enteric methane production from buffaloes and lowered environmental pollution from ruminant production systems. A discernible positive impact on growth, milk production, and immunity status was evident in supplemented buffaloes.
Impact of propylene glycol supplementation during early postpartum period on serum me tabolites and reproductive performance in Nili-Ravi buffalo
Authors: Saleem Akhtar Muhammad , Khan Rehman , Ahmad Ejaz , Ahmad Tanveer , Channa Aijaz Ali , Rehman Khan Muhammad Irfan ur
Published: January 2025

The present study investigated the effect of propylene glycol supplementation during the early postpartum period on serum metabolites in buffalo. Nili Ravi buffalo (n=25) were randomly assigned to one of two groups, i.e., Treatment Group (n=15) and Control Group (n=10). In the experimental group, propylene glycol (500 ml/  animal/ day) supplementation started from day 7 to day 50 postpartum. These animals were under observation for weekly measurements from 3 weeks pre-partum to 10 weeks postpartum. Blood sampling was done weekly for glucose, insulin, and beta-hydroxybutyric acid analysis. Propylene glycol supplementation did not affect body weight and milk yield (p> 0.05). Serum glucose and insulin concentration were significantly increased (p< 0.05), and ketone body levels were reduced (p< 0.05) shortly after propylene glycol supplementation. It was concluded that propylene glycol during the early lactation period in Nili-Ravi buffalo effectively increased serum glucose and insulin levels and lowered blood ketone body levels, which reduced the risk of ketosis.
Penguatan Pemahaman Pelaksanaan Projek Penguatan Profil Pelajar Pancasila di Satuan Pendidikan
Authors: Susetyarini Eko , Baiduri Baiduri , Muslim Muslim , Sultan Mahi , Haryani Nia
Published: January 2025

Projek Penguatan Profil Pelajar Pancasila dirancang untuk menciptakan peserta didik Indonesia yang memiliki kompetensi abad ke-21 sekaligus mencerminkan nilai-nilai Pancasila. Program ini dilaksanakan melalui lokakarya berbasis pendekatan andragogi yang melibatkan pengawas sekolah, kepala sekolah, dan komite pembelajaran di Kabupaten Dompu. Teknik pelaksanaan meliputi sesi refleksi, eksplorasi konsep, diskusi kolaboratif, demonstrasi kontekstual, hingga penyusunan kerangka projek dan asesmen yang efektif. Teknik analisis keberhasilan program dilakukan melalui pengukuran pre-test dan post-test, observasi dokumentasi, serta rubrik penilaian rancangan projek dan asesmen. Hasil kegiatan menunjukkan peningkatan kemampuan peserta dalam merancang dan melaksanakan projek yang efektif, serta tercapainya indikator keberhasilan berupa peningkatan kualitas pembelajaran, motivasi belajar siswa, dan penguatan budaya positif di sekolah.
Mendelian randomization analysis of the causal association between immune cells and pancreatic cancer
Authors: Nov Pengkhun , Touch Socheat , Sou Syphanna , Kouy Samnang , Wang Duanyu , Li Jiqiang
Published: January 2025

Aims: Pancreatic cancer (PC) is a highly lethal malignancy with limited treatment options. Tumor-infiltrating immune cells have been implicated in the progression and prognosis of PC. However, the causal role of immune cell populations in pancreatic cancer development and progression remains unclear. This study aims to elucidate the causal relationships between specific immune cell populations and the risk of pancreatic cancer, addressing gaps in current understanding.

Method: We conducted an extensive two-sample Mendelian randomization (MR) analysis. Using publicly available genetic data, we investigated the causal relationship between 731 immune cells and PC. We used inverse variance weighting (IVW) and weighted medians for MR analyses and used sensitivity analyses to assess heterogeneity and pleiotropy.

Results: In terms of the association between immune cells and PC, we found that CD62L- HLA DR++ monocyte % monocytes (OR = 1.1081, 95% CI = 1.0175–1.2068, p = 0.0184), SSC–A on HLA DR+ CD8br (OR = 1.1068, 95% CI = 1.0024-1.2221, p = 0.0448), CD64 on monocytes (OR = 0.8594, 95% CI = 0.8021-0.9207, p 0.001), double-negative (DN) (CD4-CD8-) NKT %T cells (OR = 0.8712, 95% CI = 0.7802-0.9728, p = 0.0143), and SSC–A on HLA DR+ CD4+ cells (OR = 0.8902, 95% CI = 0.8028-0.9870, p = 0.0272) were strongly associated with PC. Among them, CD62L- HLA DR++ monocyte % monocytes and SSC–A on HLA DR+ CD8br are the risk factors, while CD64 on monocytes, DN (CD4-CD8-) NKT %T cells, and SSC–A on HLA DR+ CD4+ cells are protective factors for PC.

Conclusion: Our analysis provides evidence for a causal relationship between specific immune cell populations and PC. Targeting immune cell populations with therapeutic interventions such as immunotherapies may hold promise for improving outcomes in PC patients. Further studies are warranted to validate these findings and explore the underlying mechanisms involved in the immune response to PC.
An Evaluation of Sports Nutrition Knowledge and Influencing Factors in NCAA Division III Athletes
Authors: Berends Kerrie , Wierenga Michael , Frens Madeline
Published: January 2025

Introduction: This study evaluated the sports nutrition knowledge of NCAA Division III (DIII) athletes, examining the influence of demographic and sport-specific factors. Nutrition is a critical component of athletic performance, recovery, and overall health, yet prior research indicates collegiate athletes often lack adequate nutrition knowledge.  
Methods: A total of 412 athletes, representing 17 different sports across endurance, power, and skill categories, completed the validated Abridged Nutrition for Sport Knowledge Questionnaire (A-NSKQ). The sample included freshmen through fifth-year senior athletes, predominantly Caucasian (85%).
Results: The average A-NSKQ score was 17.1 out of 35 (48.9%), indicating suboptimal knowledge. Significant differences were found across multiple variables including sex (p=0.0018), class rank (p=0.0023), sport played (p<0.0001), and previous nutrition education (p=0.0011). A multiple regression analysis identified sport played (54%), class rank (16%), sex (13%), and prior nutrition education (11%) as significant predictors of A-NSKQ scores (R2 = 0.26, p < 0.01).
Conclusions: These results highlight the need for targeted, evidence-based nutrition education in DIII programs. Future research should explore how improved knowledge influences dietary practices, athletic performance, and effective delivery of nutritional education.
“An Efficient Synthesis of Hybrid Chalcone And Acetyl Pyrazoline Derivatives As Potent Antimycobacterial And Antimicrobial Agents”
Authors: Tukaram Mr. Walke Sudhir , Patel Dr. Rajnikant
Published: January 2025

The continuous increase of bacteria and viruses that are able to withstand antibiotics is a major problem for human health across the world. We must find new ways to treat these infections immediately. There is an urgent need to investigate new chemical scaffolds and hybrid molecules that may provide improved effectiveness, as many widely used antibiotics and antimycobacterial medicines are losing some of their effectiveness. To enhance the therapeutic benefits of many bioactive substances, one potential approach to drug design is to synthesize hybrid molecules that integrate their pharmacophores. Particularly in the fields of antibacterial and antimycobacterial therapies, hybrid chalcone and acetyl pyrazoline derivatives have attracted a lot of interest owing to their varied biological activities.
Chalcones are naturally occurring chemicals that belong to the flavonoid family. They have shown a broad range of biological actions, such as antibacterial, anti-inflammatory, antioxidant, anticancer, and antimalarial characteristics. They can be easily modified chemically and used to produce new derivatives due to their very adaptable α, β-unsaturated ketone system and simple chemical structure. The capacity of chalcones to bind with DNA of bacteria and fungi, block enzymes, and disrupt microbial cell membranes is the main explanation for their biological activity. Chalcones are thought to be great starting points for novel antimicrobial agents because of their structural flexibility and wide range of activities.(Cheng et al., 2020)
Conversely, pyrazolines are heterocyclic molecules with five carbon atoms that have shown strong biological activity, such as antibacterial, antifungal, anticancer, and anti-inflammatory properties. The capacity of pyrazoline derivatives to suppress the development of infectious microbes including mycobacteria, fungus, and bacteria has led to a surge in their popularity. Chalcone scaffolds may have their antibacterial action amplified by adding a pyrazoline component to them. In particular, acetyl pyrazoline derivatives offer promising new avenues for antimicrobial research due to their enhanced effectiveness against a wide range of resistant bacterial strains.
Fractional Order ANFIS Sliding Mode Controller for Two-Time Scale Dynamics in PWR
Authors: Arshad Habib Malik  , Feroza Arshad  , Aftab Ahmad Memon
Published: January 2025

In this research work, a novel model of Pressurized Water Reactor (PWR) dynamics is developed with special emphasis on nuclear fuel burn-up or fuel depletion dynamics. PWR dynamics is identified and decomposed into fast and slow dynamic modes for the first time in this research work. The stiff two-time scale reactor dynamics problem is addressed, and a new sophisticated fractional order two-time scale sliding mode controller is designed. The PWR dynamics is uncertain due to three distinct operating conditions of nuclear reactor core as Beginning of Core (BOC), Middle of Core (MOC) and End of Core (EOC) synthesizing a variable structure model. The model uncertainties are estimated using Adaptive Neuro-Fuzzy Inference System (ANFIS) while different reactivity components are addressed as active disturbance or measurement noise. The novel robust control design problem is a big challenge in this research. The proposed controller is designed, tested and validated against benchmark data and found excellent in performance.
Theoretical Evaluation of Silicon Crystal Growth Using Gallium Solvent
Authors: Alijon Razzokov  , Eshchanov Khushnudbek
Published: January 2025

Semiconductor materials are of great importance throughout the world. Silicon crystals are this field's most widely used and relatively inexpensive material. Obtaining low-dislocation and defect-free silicon crystals is one of the current issues, and we theoretically investigated the production of low-defect silicon crystals from silicon-gallium melt. We considered the defects that appear in the silicon crystals grown from the solution related to the large-sized silicon nanoclusters involved in the crystal formation based on the obtained results, we showed the conditions for obtaining silicon crystals with few defects from the silicon-gallium solution.
ANALISIS TEKNIS DAN EKONOMIS PADA PENGELOLAAN AIR ASAM TAMBANG MENGGUNAKAN KAPUR TOHOR DI KPL 01 AL CIK AYIB PT BUKIT ASAM, Tbk.
Authors: Maya Matofani  , Lina Rianti  , Iranda Septa Pratama
Published: January 2025

This research aims to analyze the management of acid mine drainage (AMD) using quicklime at KPL 01 CIK AYIB PT Bukit Asam, Tbk. from technical and economic perspectives. The research method used is descriptive quantitative with primary data collection through field observations and secondary data from the company. The results show that AMD management at the site uses an active method with the addition of quicklime (CaO) in the first 5 compartments, followed by a passive method using wetlands in the next 9 compartments. The average use of quicklime is 6 sacks (180 kg) per day, capable of neutralizing the pH of AMD from 5.5 to 6.69-8.21 at the outlet. The cost of using quicklime for one month reaches Rp 8,865,000. This study concludes that AMD management using quicklime at the site is technically effective in neutralizing pH according to quality standards and needs further analysis in terms of its economic efficiency.
Evaluating the Influence of Blast Design in Quarrying Operations on the Environment
Authors: ADESIDA Patrick Adeniyi , OLADAYO Olawande Omoyosola
Published: January 2025

Blasting operations in quarrying have significant environmental impacts that must be managed carefully. Ground vibrations, air blasts, and dust generation are primary concerns. Understanding blast design parameters' impact on fragmentation efficiency and environmental consequences is essential for advancing quarrying practices. The primary challenge in quarrying is to balance these competing demands: achieving optimal rock fragmentation while minimising adverse environmental effects. This research aims to evaluate the influence of blast design on the environment by providing a detailed assessment of how different parameters affect productivity and environmental impact. This research investigates how various blast design parameters—specifically charge weight, blast pattern, timing sequences, and explosive types—impact the environment. The results show that none of the selected quarries complied with the regulated standard. However, factors that promoted low blasting vibration effects on the environment were bench height of not more than 10 m, very low charge load density of approximately 2 tonnes, and consistent application of non-electric detonators and connectors. Locations with a high bench height of 13.8 m recorded noise levels of 105 to 110 dB, fly rocks within 225 to 280 m, and a backbreak of 3.5 to 6.0 m, while locations with a bench height of 10 m and below recorded noise levels of 79 to 91 dB at 300 m away from the centre of the blast, while the backbreak and the fly rock distances are within 1.6–2.2 and 170-216, respectively. Siting a residential building over 1000 meters away from the quarry is significant for the control and reduction of vibration effects to a negligible degree. Therefore, the government should contract quality control monitoring to private companies for effective monitoring.
Expanding the Market through Digitalization: Identification Tool for MSME’s to Their Potential Costumer
Authors: Hafianti Silvi , Widiastuti Nur , Apriani Triana
Published: January 2025

This research aims to provide simple tools for MSMEs to understand the market conditions they are facing. Moreover, this research also intended to provide information for MSMEs on where customers can buy their products and their ability to access the digital marketing platform they will use. The expected users of these tools are MSMEs. Hence, the important aspect of constructing the tools highlighted in this research is simple, general, and inexpensive. Three key questions try to answer in this research are (1) where the customers are; (2) whether there are potential customers for MSMEs; and (3) do they have the ability to access the digital marketing platform that the MSMEs will try to use in this pandemic. This research proposes two types of indicators for targeted digital marketing. The first indicator is the regional indicator, which shows the capacity of the regions to spend or consume. The second indicator is a household indicator that shows the purchasing ability to consume and the ability of a household to access a digital platform. The data is estimated at the provincial level using annual data obtained from Statistics Indonesia. The results show that the provinces in Java currently have the highest potential for accessing digital platforms. However, analyzing the data using the growth variables shows a big potential for provinces in Kalimantan and Sulawesi as the next destination for expanding the digital platform.
Influence of Entrepreneurial Education and Family Support on Students' Interest in Entrepreneurship
Authors: Harun Basalamah Salma , Clymenia Agripina , Nofisks Dara Jingga Puti , Nandang Nandang , Fauziyah Azizah
Published: January 2025

One of the main problems in Indonesia that affects the economy is unemployment. The unemployment rate in Indonesia in August 2023 was recorded at 5.32%, down from 5.86% the previous year. Entrepreneurial knowledge is an important concept in the world of business and entrepreneurship, which includes the understanding and skills needed to start and manage a business. To overcome this problem, the government encourages students to enter the world of entrepreneurship as an effort to overcome the gap between the number of workforce and available job opportunities. Entrepreneurial knowledge and entrepreneurial motivation are important factors that can influence students' interest in entrepreneurship. This study aims to examine the Influence of Entrepreneurial Knowledge and Family Roles on Entrepreneurial Interest in Entrepreneurship Study Program Students at the Indonesian Education University, the object of study is Entrepreneurial Interest, which acts as a dependent variable. Meanwhile, Entrepreneurial Knowledge and Family Roles act as independent variables. The subjects of this study were students of the Entrepreneurship Study Program at the Indonesian Education University. The results of this study can be concluded that entrepreneurial knowledge and the role of the family are the most important factors in forming an entrepreneurial behavior. The positive influence between entrepreneurial knowledge and the role of the family on the interest in entrepreneurship together will provide benefits in increasing student motivation and readiness to become entrepreneurs.
Local Government Policy on Handling Stunting in Mandailing Natal Regency
Authors: Puansya Irman , Pulungan Darman Syah , Harahap Rahmat HarisSaputra , Telaumbanua Anita
Published: January 2025

Stunting is an issue that requires serious attention from the Central Government to the Regional Governments, particularly the Regional Government of Mandailing Natal Regency. This is because Mandailing Natal Regency is one of the regions in North Sumatra with a high stunting rate, reaching 47.7% in 2021, placing Mandailing Natal at the top rank in North Sumatra for stunting cases, according to the Indonesian Nutrition Status Study (SSGI). In 2022, Mandailing Natal dropped to third place with a stunting rate of 34.2%. However, this figure is still far from the national target set for Mandailing Natal, which is 14% by 2024. This study aims to analyze the policies of the Mandailing Natal Regional Government to reduce the stunting rate to 14% by 2024 and examine the various challenges faced. The method used in this research is qualitative descriptive analysis. Data collection techniques include interviews, observation, and documentation. The informants for this study included officials from the Mandailing Natal Health Office, Family Planning Office, village heads, and village assistants. The study found that the Mandailing Natal Government has implemented cross-sectoral policies, specific interventions, and the "Foster Father" program to reduce stunting. Success depends on policy continuity, program optimization, and increasing public awareness. The main challenges are limited funding, poor sanitation, and cultural barriers.
Evaluating the Use of QRIS in MSME Services: Insights for Financial Education in Tawang, Tasikmalaya
Authors: Hartono Muhammad Fauzan , Nandang Nandang , Ramadhani Dimas Bagus , Rosalia Indah
Published: January 2025

This study examines the use of Quick Response Code Indonesian Standard (QRIS) in Micro, Small, and Medium Enterprises (MSMEs) in Tawang District, Tasikmalaya, focusing on its impact on transaction efficiency and service quality. QRIS, a digital payment system introduced by Bank Indonesia, enables cashless, contactless payments through smartphones, thus offering a solution to slow cash transactions and improving operational efficiency. The research aims to explore how QRIS adoption enhances MSME competitiveness by increasing market reach, reducing operational costs, and improving customer service, particularly in post-pandemic Indonesia. Data collected through interviews, observations, and documentation from MSME owners in the district reveal that businesses such as Rumah Papi Bakery, Warteg Kahrisma Bahari, Bosqu Barber, and Azka Laundry have benefited from QRIS in terms of transaction speed, customer satisfaction, and financial management. The study also addresses the challenges of QRIS adoption, such as the need for a stable internet connection and public understanding of the system.
Teacher Emotional Intelligence: Analysis Based on Work Commitment, Spiritual Intelligence, and Pedagogical Competence of Arabic Language Teachers in Bengkalis Regency
Authors: Putra Muhammad Wira Dana , Hermita Neni , Isjoni Isjoni
Published: January 2025

Emotional intelligence greatly affects individual teachers such as Arabic language teachers, it can be seen that emotions act as an impetus from within the teacher as a step to act and Arabic language teachers who are identical with high emotionality can affect students. This study aims to determine the influence of variables (1) work commitment on emotional intelligence, (2) spiritual intelligence on emotional intelligence (3) pedagogic competence on emotional intelligence, (4) work commitment to spiritual intelligence, (5) work commitment to pedagogic competence (6) spiritual intelligence to pedagogic competence, (7) work commitment, intelligence and pedagogic competence on emotional intelligence. Respondents of this study were Arabic language teachers who taught at MI / SD, MTs / SMP, and MA / SMA Negeri and Private in Bengkalis Regency. The population was 125 people with a sample of 96 Arabic language teachers. Data analysis using path analysis. The research findings show that work commitment has an indirect impact on emotional intelligence (0.368), spiritual intelligence has an indirect impact on emotional intelligence (0.549), pedagogical competence has a direct impact on emotional intelligence (0.714), and work commitment has a direct impact on spiritual intelligence (0.628), 628), there is a direct influence between work commitment on pedagogical competence, the magnitude of the direct influence between work commitment on pedagogical competence is 0.383, there is a direct influence between spiritual intelligence on pedagogical competence, the magnitude of the direct influence between spiritual intelligence on pedagogical competence is 0.492. Thus it can be concluded that there is a direct and indirect influence between work commitment, spiritual intelligence and pedagogical competence on the emotional intelligence of Arabic language teachers in Bengkalis Regency.
Narrative Representation of Mental Health and Marginalization in Joker: A Cultural Literature Analysis
Authors: Jamalullail Ali Ridho , Ahzani Nizam
Published: January 2025

This study examines the narrative and cultural representation of mental health and marginalization in the 2019 film Joker through a qualitative approach. Framed as a form of visual literature, Joker offers a profound lens to explore the stigmatization of mental illness and the societal alienation faced by marginalized individuals. Utilizing narrative analysis and cultural studies, our study investigates key elements such as characterization, symbolism, and thematic structures to uncover how the film critiques societal attitudes and systemic failures related to mental health. The findings reveal that Joker humanizes its protagonist, Arthur Fleck, while exposing the broader societal and institutional mechanisms that perpetuate stigma and inequality. This study contributes to the growing body of literature on mental health and cultural studies by emphasizing the role of visual media in challenging dominant narratives and fostering critical discourse. The implications extend to fields such as literature, cultural representation, and education, advocating for the use of media as a tool for promoting mental health awareness and social inclusion.
Equivalent transformation of differential and integral equations in hyperbolic plane
Authors: Zhang Ronghang , Lan Yue , Xu Zhenyu
Published: January 2025

Hyperbolic numbers, serving as an extension of real numbers, exhibit an algebraic structure akin to complex numbers, constituting commutative rings with zero divisors that stem from two real numbers. This paper delves into the exploration of the equivalence relation between the solutions of differential equations and integral equations within the realm of the hyperbolic plane. The pivotal finding of this study reveals that the solutions of hyperbolic differential equations and integral equations are inherently equivalent. Such a discovery not only solidifies the groundwork for delving into hyperbolic differential equations but also injects a renewed impetus into the advancement of physics. By bridging the gap between differential and integral equations in the hyperbolic domain, our research paves the way for a deeper understanding of hyperbolic numbers’ mathematical structures and their applications in the physical sciences, thereby opening up new avenues for exploration and discovery.