bluuebunny/crossref_metadata_2025 huggingface dataset:
Laporan Keuangan dan Prediksi Kebangkrutan Perusahaan
Authors: Masdiantini Putu Riesty , Warasniasih Ni Made Sindy
Published: July 2020

This study aims to determine differences in bankruptcy predictions at company’s sub-sector of cosmetics and household listed on the Indonesia Stock Exchange (IDX) using the Altman model, Springate model, Zmijewski model, Taffler model, and Fulmer model, and to determine the bankruptcy prediction model that is the most accurate of the five bankruptcy prediction models. This study uses secondary data in the form of company financial statements for the period 2014-2018. Data analysis techniques in this study used the Kruskal-Wallis test. The results showed there were differences in bankruptcy predictions using the Altman model, Springate model, Zmijewski model, Taffler model, and Fulmer model. The Zmijewski, Taffler, and Fulmer models have the same accuracy level of 100% so that the three prediction models are the most accurate prediction models for predicting the potential bankruptcy at companies sub-sector of cosmetics and household listed on the IDX.
Menelisik Akar Kegaduhan Bangsa Indonesia Pasca Disetujuinya Hasil Revisi UU KPK Dalam Perspektif Pancasila
Authors: Santika I Gusti Ngurah
Published: July 2020

Penelitian ini dilatarbelakangi oleh kegaduhan yang terjadi di Indonesia pasca disetujuinya hasil revisi UU KPK. Demonstrasi diberbagai daerah yang dilakukan mahasiswa untuk menyampaikan aspirasi penolakannya terhadap hasil revisi UU KPK malah berujung bentrokan dengan aparat keamanan. Penelitian ini bertujuan untuk menelisik akar kegaduhan bangsa indonesia pasca disetujuinya hasil revisi UU KPK dalam perspektif Pancasila. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif. Pengumpulan data dilakukan dengan studi dokumentasi dan literatur. Hasil penelitian ini menunjukan bahwa Pancasila yang merupakan sumber kebenaran dan kedamaian bagi Indonesia tidak digunakan sebagai rujukan normatif oleh segenap komponen bangsa dalam menjalankan kedudukan dan perannya. DPR dan Presiden dalam merevisi UU KPK kurang terbuka terhadap aspirasi rakyat Indonesia. KPK tidak memainkan perannya sebagai lembaga penegak hukum yang secara yuridis bertugas melaksanakan UU. Pers tidak profesional dan independen dalam menyajikan imformasi ke publik. Mahasiswa cenderung bertindak anarkis dalam menyampaikan aspirasi politiknya.Kata kunci: Revisi Undang-Undang; Komisi Pemberantasan Korupsi; Pancasila
Persepsi Wisatawan Terhadap Objek Daya Tarik Wisata Tenganan Pegringsingan, Kabupaten Karangasem
Authors: Apriani Ni Luh , Suharsono Naswan , Tripalupi Lulup Endah
Published: July 2020

The purpose of this study was to determine the tourist’s perceptions about Tenganan Pegringsingan tourist attraction. This type of research is a qualitative descriptive study. The population of the study is tourists visiting Tenganan Pegringsingan with an infinite number and 100 respondents were taken using incidental sampling techniques. Data were collected using a questionnaire and analyzed with descriptive analysis techniques. The results showed that tourists' perceptions of Tenganan Pegringsingan tourist attraction in terms of the dimensions of attractions, amenities and accessibility were very amenable. That means Tenganan Pegringsingan tourist attraction has a unique nature, tradition and culture. The existence of a tracking tour, a friendly community, a safe tourist attraction environment, no entrance fee (there are donations that can contribute voluntarily), supporting facilities are available and have an easy access to Tenganan Pegringsingan tourist attraction
Analisis Keaktifan Mahasiswa dalam Proses Pembelajaran Statistika Mulitvariat
Authors: Irsyad Taufik , Wuryandini Endang , Yunus Mahmud , Hadi Dwi Prastiyo
Published: July 2020

This research is motivated by the condition of students in the learning process of multivariate statistics courses. In the matter of data input practice, data output, and data interpretation. Students tend to only follow lectures and are less active in asking questions. Students are less active in looking for additional material beyond the material taught by the lecturer. The research method uses a qualitative case study type approach. The research object consisted of 23 students who took multivariate courses, the Chair of the Study Program and a lecturer in Economic Education. Data collection techniques used were observation, interviews, and documentation. The results of this study are multivariate statistical learning courses performed well. The process of teaching and learning activities prioritize student activity as evidenced by the practice carried out in each lecture. The Submission of material is done using English. Student activeness is still lacking because students are less active in asking questions. Student motivation tends to be low in finding information about lecture material that has been taught or will be taught. The conclusion of this study is that discipline, commitment, and encouragement from within students are important. Personal motivation affects more activeness. This research has implications as a contribution to lecturers in order to be able to increase encouragement from within students in order to increase activity in the learning process.
Pendidikan Formal Bagi Masyarakat Desa Kayu Bulan Kecamatan Kapuas Tengah Kabupaten Kapuas
Authors: Alexandro Rinto , Putri Windy Utami
Published: July 2020

The purpose of this study was to find out how formal education is for the Community of Desa Bulan Bulan Kapuas Tengah District Kapuas District. While the type of research is qualitative research. The subjects of the study were the village head, parents of school age children and school age children. Data collection techniques are in-depth interviews, observation and documentation. The data analysis technique used in this study was Odel Miles and Huberman. Activities in data analysis are data reduction, data display, and conclusion drawing / verification. The results of this study indicate that formal education for the people of Kayu Bulan Village, Kapuas Tengah District, Kapuas Regency, is a place to get knowledge and benefit young people to improve their quality. The supporting factors for formal education in Kayu Bulan Village are the support from parents to children to attend formal education, the existence of buildings, textbooks, and equipment and costs needed at school. While the inhibiting factor they feel is the mindset of children who do not consider school is something serious, there are various delinquents of adolescents who have begun to influence children in Kayu Bulan Village and the emergence of a child's laziness to attend formal education due to teachers who are disliked by children, and an invitation from parents to come to work
Environmental Conservation Through Study Value of Bali Aga Tenganan Pegringsingan Community Culture
Authors: Wijana Nyoman , Setiawan I Gusti Agung Nyoman , Mulyadiharja Sanusi , Wesnawa I Gede Astra , Rahmawati Putu Indah
Published: July 2020

This research aimed to know the implementation of environmental conservation in terms of cultural value orientation, including humanistic nature orientation, man-nature orientation, time orientation, activity orientation, and relational orientation. The population of this research was the entire community in traditional village Tenganan Pegringsingan, Karangasem, Bali. This research sample amounted to 25 people, consisting of the conventional village apparatus, community leaders, and the general public. Methods of data collection were the method of observation, interview, questionnaire, and checklist. The collected data were analyzed descriptively. This research indicated that the orientation of cultural values of humanistic nature orientation and man-nature orientation had an excellent quality. The time orientation, activity orientation, and relational orientation parameters had good quality. Culture in the study community generally showed a positive thing, so the impact of culture on the quality of the environment, in general, was excellent. The results of observations in the field revealed that there were all community activities at Tenganan Pegringsingan that could not cause environmental pollution. Therefore, the role of traditional regulation or awig-awig to regulate environmental and social-culture.
Pengaruh Tingkat Kepadatan Penduduk Terhadap Indeks Pembangunan Manusia di Provinsi Bali
Authors: Antara I Gede Made Yudi , Suryana I Gede Putu Eka
Published: July 2020

Penduduk dalam suatu wilayah sangat menentukan pembangunan di suatu wilayah. Sumber daya manusia yang erat kaitannya kuantitas dan kualitas penduduk harus menjadi perhatian pemerintah demi lancarnya pembangunan. Kuantitas dapat dilihat dari jumlah dan kepadatan penduduk, sedangkan kualitas penduduk suatu wilayah dapat dilihat dari Indeks Pembangunan Manusia (IPM) yang dicapai suatu wilayah. Provinsi Bali dengan kepadatan penduduk 743 jiwa/km2  memiliki IPM dengan kategori tinggi berdasarkan klasifikasi yang dikeluarkan oleh Badan Pusat Statistik. Tujuan dari penelitian ini adalah untuk mengetahui sejauh mana kuantitas penduduk yaitu kepadatan penduduk berpengaruh terhadap kualitas penduduk yang dilihat dari capaian IPM. Data sekunder yang diperoleh kemudian dianalisis secara kuantitaif dengan analisis regresi untuk mengetahui pengaruh dari kepadatan penduduk terhadap capaian IPM dan divisualisasikan dengan pemetaan digital menggunakan Arcview GIS 3.3. Hasil yang diperoleh bahwa kepadatan penduduk berpengaruh secara siginifikan terhadap capaian IPM, sehingga menunjukkan bahwa jumlah penduduk yang besar harus diiringi peningkatan kualitas sumber daya manusia.
Injuries and poisonings associated with e-cigarettes and vaping substances, electronic Canadian Hospitals Injury Reporting and Prevention Program, 2011–2019
Authors: McFaull Steven R. , Do Minh T. , Champagne André , Bang Felix
Published: July 2020

Electronic cigarettes are devices that deliver nicotine to the user by heating an e-liquid. In Canada, the Tobacco and Vaping Products Act became law on May 23, 2018. The purpose of this study was to describe the cases of injuries and poisonings associated with e-cigarette and vaping substances that presented to Canadian emergency departments within the electronic Canadian Hospitals Injury Reporting and Prevention Program network between 2011 and 2019. A total of 68 cases were retrieved (54.4% males). Of the 68 cases, 8 occurred between 2011 and 2014, while 35 (51.5%) occurred in 2018 or 2019. Ingestions, inhalations and burns were observed.
Prácticas performáticas feministas. Cuestionando las nociones de gusto social
Authors: Carod Natalia
Published: July 2020

El presente artículo indaga en prácticas performáticas utilizadas como medios principales de denuncia y de visibilización de la violencia de género en los últimos años por artistas y por activistas latinoamericanas. En contextos de lucha feminista la acción performática agencia discursos que han sido expulsados y enviados a la periferia del campo social dominante. Se considera que dichos discursos producen una disputa por el capital simbólico de lo que es entendido por política y, por ende, de lo que es entendido por estética, cuestionando la noción hegemónica de gusto social asociada al imperativo heteropatriarcal. Para ello, se analizan tres manifestaciones performáticas acontecidas en los últimos cinco años en Chile y en la Argentina, tomando como referencia la primera movilización Ni Una Menos en la Argentina en el año 2015.
An Elementary Proof for the Decomposition Theorem of Wright Convex Functions
Authors: Páles Zsolt
Published: July 2020

The main goal of this paper is to give a completely elementary proof for the decomposition theorem of Wright convex functions which was discovered by C. T. Ng in 1987. In the proof, we do not use transfinite tools, i.e., variants of Rodé’s theorem, or de Bruijn’s theorem related to functions with continuous differences.
Multifunctionality of Agriculture as a Significant Factor for Sustainable Rural Development of the Republic of Serbia
Authors: Ristić Lela , Despotović Danijela , Dimitrijević Miloš
Published: July 2020

The need for a modern agricultural development conditioned the concept of multifunctionality of agriculture. Multifunctionality of agriculture is often considered as a useful tool for achieving economic and sustainable development goals. It is increasingly gaining importance in the field of sustainable rural development by linking traditional and contemporary agricultural functions. Namely, sustainability of development requires food for people, but also other positive social, ecological and economic effects. The aim of this paper is to identify the most important indicators of agriculture from the point of multifunctionality of agriculture as a factor for sustainable rural development of the Republic of Serbia, and also compare rural indicators of the Western Balkan countries. The multivariate linear regression in the paper showed that more indicators of agriculture have impact on economy than on sustainable development of the Republic of Serbia, with particularly significance of rural population and its activity. Thereby, some statistical tests showed a decrease in rural population and employment in agriculture of the Western Balkan countries. It is concluded that support to multifunctionality of agriculture is of particular importance for sustainable rural development of the Republic of Serbia.
Structure and function of HECT E3 ubiquitin ligases and their role in oxidative stress
Authors: Qian Hao , Zhang Ying , Wu Boquan , Wu Shaojun , You Shilong , Zhang Naijin , Sun Yingxian
Published: July 2020

Ubiquitination is a modification after protein transcription that plays a vital role in maintaining the homeostasis of the cellular environment. The Homologous to E6AP C-terminus (HECT) family E3 ubiquitin ligases are a kind of E3 ubiquitin ligases with a C-terminal HECT domain that mediates the binding of ubiquitin to substrate proteins and a variable-length N-terminal extension. HECT-ubiquitinated ligases can be divided into three categories: NEDD4 superfamily, HERC superfamily, and other HECT superfamilies. HECT ubiquitin ligase plays an essential role in the development of many human diseases. In this review, we focus on the physiological and pathological processes involved in oxidative stress and the role of E3 ubiquitin ligase of the HECT family.
The role of mitochondria in vascular calcification
Authors: Wang Pengbo , Zhang Naijin , Wu Boquan , Wu Shaojun , Zhang Ying , Sun Yingxian
Published: July 2020

Vascular calcification (VC) was defined as the ectopic deposition of calcium–phosphorus complexes on the blood vessel walls. It was a process involving multiple factors and mechanisms, covering the phenotype transition of vascular smooth muscle cells (VSMCs) and release of microvesicles. It was a common end-stage alteration of chronic diseases such as cardiovascular disease and chronic kidney disease. Increasing evidence indicates that mitochondria were involved in the development of VC. Mitochondria provided energy to cells, maintained the stability of cell functions, and participated in a variety of biological behavior. Oxidative stress, autophagy, apoptosis, and mitochondrial DNA (mtDNA) damage could affect the development of VSMCs calcification by alteration of mitochondrial function. This article reviewed the mechanism of calcification and the role of mitochondria in VC, aiming to raise a novel insight into drug development and clinical treatment.
Autoimmune hepatitis: Clinical characteristics and predictors of biochemical response to treatment
Authors: Tasneem Abbas Ali , Luck Nasir Hassan
Published: July 2020

Background and Objectives

Autoimmune hepatitis (AIH) is an important cause of chronic liver disease. Aim of this study was to evaluate the clinical characteristics and factors predicting response to treatment in patients with AIH.

Methods

In this prospective observational study, all patients diagnosed with AIH from 2017 to 2019 were included. Biochemical response to the treatment was checked three months after the start of the treatment. Response was considered good if transaminases normalized, or poor if either remained persistently elevated or improved partially.

Results

Of the total 56 patients, 41 (73.2%) were females. Mean age was 29.5 (±16.9) years. About half (53.6%; n = 30) the patients were aged < 25 years and majority [47 (83.9%)] were cirrhotic. Autoimmune serology was negative in 20 (35.7%). Seronegativity was associated with severe necroinflammation (P = 0.015) and esophageal varices (P = 0.021). Response to treatment was good in 34 (60.7%). Bivariate analysis showed that good response to treatment was associated with pre-treatment serum IgG level > 20 g/L (P = 0.024), presence of pseudorosettes on histopathology (P = 0.029) and three months post-immunosuppression serum total bilirubin < 2mg/dL (P < 0.001). Multivariate logistic regression analysis showed that only pre-treatment serum IgG >20 g/L (P = 0.038) and post-treatment serum total bilirubin <2 mg/dL (P = 0.004) were independent predictors of good response to treatment.

Conclusion

Majority of AIH patients in our study were young and cirrhotic. A negative autoimmune serology does not rule out AIH and liver biopsy may be required to confirm the diagnosis. Seronegative AIH rapidly progresses to advanced liver disease. Response to treatment is good with pre-treatment IgG > 20g/L and post-treatment total bilirubin < 2 mg/dL.
Seroprevalence of antibodies against Anaplasma phagocytophilum and Borrelia burgdorferi in horses (Equus caballus) from northern Algeria
Authors: Laamari Abdelouahab , Azzag Naouelle , Tennah Safia , Derdour Salima-Yamina , China Bernard , Bouabdallah Ryhan , Ghalmi Farida
Published: July 2020

Introduction

Horses (Equus caballus) are susceptible to tick-borne diseases. Two of them, Lyme borreliosis due to Borrelia burgdorferi and granulocytic anaplasmosis due to Anaplasma phagocytophilum were investigated in Algerian horses. The diseases have been less extensively studied in horses and results pertinent to Algeria have not been published.

Material and Methods

Blood samples were obtained from 128 horses. IgG antibodies directed against Anaplasma phagocytophilum and Borrelia burgdorferi were detected by an indirect immunofluorescence antibody test (IFAT) and ELISA. The potential effects of age, gender, breed, and health status on seropositivity were also evaluated.

Results

Using IFAT, 28 (21.8%) and 25 (19.5%) animals were positive for B. burgdorferi and A. phagocytophilum, respectively. Using ELISA, 19 (14.8%) and 33 (25.9%) animals were positive for these bacteria.

Conclusion

The study shows that horses in Algeria are exposed or co-exposed to tick-transmitted zoonotic bacterial species.
Detection of myxoma virus in the classical form of myxomatosis using an AGID assay: statistical assessment of the assay’s diagnostic performance
Authors: Kwit Ewa , Osiński Zbigniew , Lavazza Antonio , Rzeżutka Artur
Published: July 2020

Introduction

The aim of the study was to estimate the diagnostic sensitivity (DSe) and specificity (DSp) of an agar gel immunodiffusion (AGID) assay for detection of myxoma virus (MYXV) in the classical form of myxomatosis and to compare its diagnostic performance to that of molecular methods (IAC-PCR, OIE PCR, and OIE real-time PCR).

Material and Methods

A panel of MYXV-positive samples of tissue homogenates with low (1 PCR unit – PCRU) and high (3,125 PCRU) virus levels and outbreak samples were used for method comparison studies. The validation parameters of the AGID assay were assessed using statistical methods.

Results

The AGID attained DSe of 0.65 (CI95%: 0.53–0.76), DSp of 1.00 (CI95%: 0.40–1.00), and accuracy of 0.67 (CI95%: 0.55–0.76). The assay confirmed its diagnostic usefulness primarily for testing samples containing ≥3,125 PCRU of MYXV DNA. However, in the assaying of samples containing <3,125 PCRU of the virus there was a higher probability of getting false negative results, and only molecular methods showed a 100% sensitivity for samples with low (1 PCRU) virus concentration. The overall concordance of the results between AGID and IAC-PCR was fair (ĸ = 0.40). Full concordance of the results was observed for OIE PCR and OIE real-time PCR when control reference material was analysed.

Conclusions

Findings from this study suggest that AGID can be used with some limitations as a screening tool for detection of MYXV infections.
Genetic diversity and structure of Oriental and European beech populations from Iran and Europe
Authors: Bijarpasi Mahboobeh Mohebi , Müller Markus , Gailing Oliver
Published: July 2020

Genetic variation is a major component of plant development and adaptation, and recent studies have shown that genetic variation among plant species can have important ecological effects. Oriental beech (Fagus orientalis Lipsky) is a dominant tree species in the Hyrcanian forests, where it occupies approximately 18 % of the forested area. In this study, nine expressed sequence tag simple sequence repeat (EST-SSR) markers were used to determine the genetic diversity and structure of Iranian Oriental beech populations growing at different altitudes. We further compared the genetic structures of the Iranian populations to a F. orientalis and a Fagus sylvatica L. population from the hybrid zone of the two taxa in southeast Europe, and to a F. sylvatica population from central Europe. All populations showed a high genetic diversity, which was similar to other F. orientalis and F. sylvatica populations from Europe. The genetic differentiation among Iranian beech populations was very low. In contrast, distinct genetic differentiation was found between the Iranian populations and the analyzed European populations (F. orientalis and F. sylvatica). One EST-SSR was identified to differentiate (GST
: 0.503) between F. orientalis and F. sylvatica with very pronounced allele frequency differences between taxa. Specifically, the Fagus sylvatica characteristic allele 189 was almost absent from all Iranian populations and present in low frequencies in F. orientalis populations from other regions. This study helps to extend the knowledge of genetic diversity and genetic structure of Iranian Oriental beech populations. It further gives insights into the genetic differentiation between F. orientalis populations from the center and the edge of the species’ distribution range as well as between Oriental and European beech.
Marker-assisted selection in C. oleifera hybrid population
Authors: Feng Jin-Ling , Jiang Ying , Yang Zhi-Jian , Chen Shi-Pin , El-Kassaby Yousry A. , Chen Hui
Published: July 2020

Marker-assisted selection (MAS) is implemented to improve Camellia oleifera yield and fruit attributes for meeting China’s increased demand for new varieties development. We conducted three-generational (G0, G1, and G2) hybridization (diallel mating) and selection experiment and used Sequence-Related Amplified Polymorphism (SRAP). SRAP markers to investigate their utility in a MAS framework. The utilized SRAP markers were instrumental in hybrid authenticity and the identification of matroclinal or patroclinal inheritance presence, thus guiding mating pair selection and direction (their role as male or females). Across the studied 3 generations, estimates of genetic diversity parameters showed steady increase with percentage increase of ((G0 to G1 and G1 to G2) 9.25 and 9.05: observed number of alleles; 3.12 and 7.80: means effective number of alleles; 12.35 and 22.34: Nei‘s gene diversity; and 14.21 and 21.77: Shannon‘s index), indicating lack of diversity reduction associated with selection. Estimates of genetic distance and their correlation with heterosis were useful in guiding selection of mating pairs for achieving the desired yield and fruit attributes (fruit diameter, height, weight, and index, peel thickness, number of seeds per fruit, seed weight per fruit, and seed rate). Most yield and fruit attributes exhibited high broad-sense heritability with increasing trend over generation intervals, indicating the increased potential of hybrid breeding for this species.
Analytical approaches to the phenomenon of electronic terrorism
Authors: Awad Muna Jalal
Published: July 2020

It is the subject of electronic terrorism An important topic and reality that no one can deny Or ignore its consequences, as this kind of terrorism turns into an unknown danger And threatens everyone to its superior ability to destroy and information technology is used to infect vital facilities and thus this phenomenon threatens the safety and security of human groups and individuals due to the risk of misusing information technology.
Policies of European Union countries towards the issue of illegal immigration
Authors: Abdul Karim Mohammad Zuhair
Published: July 2020

Migration is an inherent phenomenon of human societies. It is the movement of people from a place where it is difficult to live to a better place, for socio-political reasons. Migration is either internal within one country or international between countries, And the latter may be legitimate or illegal. The European continent has become a dream for immigrants to live better. But Europe, which has received large numbers of immigrants and has become part of its social, economic and political entity, is beginning to suffer from problems  and reflections: security, economic, social and political, in light of the increasing number of immigrants in Europe, which has made European countries since the 1980s changed their policies, And start to legislate laws and procedures and conclude restrictive immigration agreements, leading to the events of September 11, 2001, which made European policies more stringent towards immigration, to develop those policies after the Arab Renaissance revolutions in 2011, And what that left, waves of displaced people headed to Europe, thousands of them were received, but as a result of economic difficulties and security and political conditions that some European countries were exposed to, Some European calls have emerged to curb immigration, In light of the differences between the EU countries and the absence of a unified European policy and vision towards immigration, Nevertheless, European countries have formed some partnerships and agreements to combat migration, as well as conducting a set of collective and unilateral restrictive immigration procedures which have led to a reduction in the number of refugees to Europe.
The Impact of President Trump's Tweets on U.S. Foreign Policy towards: Iran, Saudi Arabia and Israel
Authors: Mahmood Mohammed Salah
Published: July 2020

The research discusses President Donald Trump's tweets through a general analytical perspective of the content of these tweets. It aims at identifying the U.S. foreign policy contained in Trump's tweets and clarifying and explaining the impact of some of these tweets on foreign policy towards Iran, Saudi Arabia and Israel in order to reach the goals and objectives of these tweets. The research highlights one of the social media platforms, which is Twitter, in analyzing some of President Trump's tweets about these countries that play a pivotal role in the Middle East. At the end of the research, several findings, contents and conclusions have been found. The time scope of the research included President Trump's tweets posted on his personal Twitter account (@realDonaldTrump) in both Arabic and English from June 16, 2015 to July 30, 2019. President Trump's tweets have clearly influenced U.S. foreign policy in terms of abandoning his country's commitment to the Iranian nuclear deal, imposing sanctions on Iran, issuing a decision to move the U.S. embassy to Jerusalem, and succeeding in concluding a civil and military trade deal with Saudi Arabia
Peacebuilding requirements in post-conflict societies
Authors: Al-Dabagh Zyad Samir
Published: July 2020

The process of building peace and laying its foundations within the societies of the world, especially those newly emerging from the stage of conflict, are among the important and indispensable matters. Without peace, opportunities diminish in obtaining the essentials of a safe and normal life, and without peace, societies cannot It works and advances towards a better future.

However, peacebuilding operations in many societies emerging from conflict or those in which they live may face a set of challenges and obstacles that constitute a major obstacle to them, which necessitates searching for the best ways and means by which these obstacles can be addressed in order to build a real and effective peace that is reflected Positively on the people of those societies.
Advances and future trends in elbow arthroscopy
Authors: Robinson Paul M.
Published: July 2020

Elbow arthroscopy has evolved since its inception and is now a commonly used technique in the diagnosis and treatment of elbow pathology. It has many indications, from the removal of intra-articular loose bodies to the management of elbow osteoarthritis and fractures. In this paper, we will discuss the full spectrum of elbow arthroscopy covering recent evidence, surgical techniques, advances, and future trends.
Recent advances and future trends in shoulder arthroscopy
Authors: DeNiese Pascal , Bhatia Deepak N.
Published: July 2020

Shoulder arthroscopy has evolved significantly over the past decade. Treatment algorithms have evolved in sync with results from cadaveric, biomechanical, and clinical studies, and newer minimally invasive and biomechanically proven surgical techniques have replaced suboptimal procedures. Advances in arthroscopy have influenced three key aspects of shoulder problems: Anterior instability, rotator cuff tears, and osteoarthritis. A new frontier of “endoscopic” extra-articular procedures has evolved and these procedures have convincingly replaced traditional open surgeries. The current evidence suggests a growing trend for arthroscopic procedures in joint preservation and restoration.
Critical Benchmarking of the G4(MP2) Model, the Correlation Consistent Composite Approach and Popular Density Functional Approximations on a Probabilistically Pruned Benchmark Dataset of Formation Enthalpies
Authors: das sambit kumar , Chakraborty Sabyasachi , Ramakrishnan Raghunathan
Published: July 2020

First-principles calculation of the standard formation enthalpy, $\Delta H_f^0$~(298K), in such large scale as required by chemical space explorations, is amenable only with density functional approximations (DFAs) and some composite wave function theories (cWFTs). Alas, the accuracies of popular range-separated hybrid, `rung-4' DFAs, and cWFTs that offer the best accuracy-vs.-cost trade-off have as yet been established only for datasets predominantly comprising small molecules, hence, their transferability to larger datasets remains vague. In this study, we present an extended benchmark dataset of over two-thousand values of $\Delta H_f^0$ for structurally and electronically diverse molecules. We apply quartile-ranking based on boundary-corrected kernel density estimation to filter outliers and arrive at Probabilistically Pruned Enthalpies of 1908 compounds (PPE1908). For this dataset, we rank the prediction accuracies of G4(MP2), ccCA and 23 popular DFAs using conventional and probabilistic error metrics. We discuss systematic prediction errors and highlight the role an empirical higher-level correction (HLC) plays in the G4(MP2) model. Furthermore, we comment on uncertainties associated with the reference empirical data for atoms and systematic errors introduced by these that grow with the molecular size. We believe these findings to aid in identifying meaningful application domains for quantum thermochemical methods.
Mechanisms of Drug Solubilization by Polar Lipids in Biorelevant Media
Authors: Katev Vladimir , Vinarov Zahari , Tcholakova Slavka S.
Published: July 2020

Despite the widespread use of lipid excipients in both academic research and oral formulation development, rational selection guidelines are still missing. In the current study, we aimed to establish a link between the molecular structure of commonly used polar lipids and drug solubilization in biorelevant media. We studied the effect of 26 polar lipids of the fatty acid, phospholipid or monoglyceride type on the solubilization of fenofibrate in a two-stage in vitro GI tract model. The main trends were checked also with progesterone and danazol.

Based on their fenofibrate solubilization efficiency, the polar lipids can be grouped in 3 main classes. Class 1 substances (n = 5) provide biggest enhancement of drug solubilization (>10-fold) and are composed only by unsaturated compounds. Class 2 materials (n = 10) have an intermediate effect (3-10 fold increase) and are composed primarily (80 %) of saturated compounds. Class 3 materials (n = 11) have very low or no effect on drug solubilization and are entirely composed of saturated compounds.

The observed behaviour of the polar lipids was rationalized by using two classical physicochemical parameters: the acyl chain phase transition temperature (Tm) and the critical micellar concentration (CMC). Hence, the superior performance of class 1 polar lipids was explained by the double bonds in their acyl chains, which: (1) significantly decrease Tm, allowing these C18 lipids to form colloidal aggregates and (2) prevent tight packing of the molecules in the aggregates, resulting in bigger volume available for drug solubilization. Long-chain (C18) saturated polar lipids had no significant effect on drug solubilization because their Tm was much higher than the temperature of the experiment (T = 37 C) and, therefore, their association in colloidal aggregates was limited. On the other end of the spectrum, the short chain octanoic acid manifested a high CMC (50 mM), which had to be exceeded in order to enhance drug solubilization. When these two parameters were satisfied (C > CMC, Tm < Texp), the increase of the polar lipid chain length increased the drug solubilization capacity (similarly to classical surfactants), due to the decreased CMC and bigger volume available for solubilization.

The hydrophilic head group also has a dramatic impact on the drug solubilization enhancement, with polar lipids performance decreasing in the order: choline phospholipids > monoglycerides > fatty acids.

As both the acyl chain length and the head group type are structural features of the polar lipids, and not of the solubilized drugs, the impact of Tm and CMC on solubilization by polar lipids should hold true for a wide variety of hydrophobic molecules. The obtained mechanistic insights can guide rational drug formulation development and thus support modern drug discovery pipelines.
Deep Learning for Prediction and Optimization of Fast-Flow Peptide Synthesis
Authors: Mohapatra Somesh , Hartrampf Nina , Poskus Mackenzie , Loas Andrei , Gomez-Bombarelli Rafael , Pentelute Bradley L.
Published: July 2020

Chemical synthesis of polypeptides involves stepwise formation of amide bonds on an immobilized solid support. The high yields required for efficient incorporation of each individual amino acid in the growing chain are often impacted by sequence-dependent events such as aggregation. Here we apply deep learning over ultraviolet-visible (UV-Vis) analytical data collected from 35,485 individual fluorenylmethyloxycarbonyl (Fmoc) deprotection reactions performed with an automated fast-flow peptide synthesizer. The integral, height and width of these time-resolved UV-Vis deprotection traces indirectly allow for analysis of the iterative amide coupling cycles on resin. The computational model maps structural representations of amino acids and peptide sequences to experimental synthesis parameters and predicts the outcome of deprotection reactions with less than 4% error. Our deep learning approach enables experimentally-aware computational design for prediction of Fmoc deprotection efficiency and minimization of aggregation events, building the foundation for real-time optimization of peptide synthesis in flow.
Organophotoredox-Catalyzed Direct C-H Functionalization of “Drug Prejudice” at Room Temperature
Authors: Chaubey Narendra , Kapdi Anant , Maity Biswanath
Published: July 2020

Organophotocatalytic C─H bond functionalization has attracted lot of attention in the past several years due to the possibility of catalysing reactions in a metal-free environment. Continuing on these lines, we repot herein an organophotoredox catalyzed C─H functionalization of imidazo[1,2-a]pyridines and related heterocycles with malonates under mild conditions providing excellent yields of the products at room temperature. Although, C─3 functionalization of imidazo[1,2-a]pyridines are known, this is the first report involving malonates as coupling partners leading to the synthesis of a range of functionalized products including Zolpidem, a sedative-hypnotic medicine.
绘画装饰在陶瓷艺术设计中的运用研究
Authors: 苗 亚楠
Published: July 2020

绘画装饰属于陶瓷艺术设计中非常重要的表现形式之一，借助于相对丰富的图案设计以及相对鲜明的色彩搭配，使得陶瓷作品的价值充分体现出来。设计人员借助于合理的线条规划，使得投资作品充分的彰显出自身的神韵，让观赏者通过陶瓷的外表体会到作品的深意。论文重点分析绘画装饰在陶瓷艺术设计中的具体运用，结合着绘画装饰在陶瓷艺术设计中的具体表现，分析两者的共同点，明确实际的运用路径。
略谈仿生设计在陶瓷设计的应用
Authors: 亓 会锁
Published: July 2020

在陶瓷设计中，仿生设计是一种比较常见的设计方式，科学运用仿生设计技艺，可让陶瓷作品生动活泼，在充满韵味的同时又趣味满满。论文在简要分析仿生设计特点的基础上，就仿生设计在陶瓷设计中的应用展开深入探究，以供参考。
陶瓷设计中传统纹饰的作用刍议
Authors: 薛 星辰
Published: July 2020

陶瓷在中国有十分悠久的历史，是人们在生产生活中的产物，伴随着中华传统文化的发展而呈现新的特点。现代陶瓷设计在发展中遇到了较大的瓶颈，往往出现千篇一律的现象，导致其艺术观赏性未能得到充分体现，限制了中国陶瓷制造业的繁荣发展。而传统纹饰在陶瓷设计当中的应用，则能够在继承优秀传统文化的基础上，创新陶瓷设计理念与方法，增强其艺术生命力。论文将通过分析传统纹饰的特点与内涵，探索陶瓷设计中传统纹饰的作用，提出陶瓷设计中传统纹饰的应用方法，为设计工作提供参考。
中国传统纹样在影视人物造型方面的传承和发展
Authors: 孙 浩
Published: July 2020

作为中国传统文化的重要组成部分，纹样的设计精致美观、类型众多，随着时代的变迁在影视人物造型方面的应用也越来越讲究和精细。精美的纹样造型，不仅可以作为亮点提升影视剧的传播度，同时也是纹样艺术在历史长河中不断传承和发展的结果。因此，应不断创新中国传统纹样艺术设计水准，满足当代人们的审美需求，与影视剧中人物造型的创作手法结合在一起，一方面突出人物性格的特点，另一方面促进艺术的传承和发扬。论文主要研究了中国传统纹样在影视人物造型方面的传承和发展。
作者对读者的情感牵引——以小说主人公 Effi Briest 为例
Authors: 曾 江垚
Published: July 2020

正如作者 Theodor Fontane 本身提到的，在其小说《Effi Briest》中，对读者的有意识的情感牵引是一个尤其重要的主题。因此，本论文以小说主角 Effi Briest 为例，来探讨作者对读者的情感牵引。诚然，人们在阅读的过程中，对主角 Effi 会产生强烈的同情与共情，甚至期望她能有一个幸福的人生，尽管 Effi 本身是一个在婚姻中不忠的女人，这在当时来说是违背了社会准则和道德观念的。相反，Effi 的丈夫 Innstetten，一个具有那个时代所有优秀品质的政客，却很少被读者喜爱，他甚至被许多读者认为是应该对整个悲剧故事负责的人。本论文的中心问题即：对 Effi 的好感牵引是如何实现的？读者能够明显感受到，Effi 在这段不幸的婚姻中一直被巨大的孤独和无助感围绕，因此人们对她产生了强烈的同情，并且认为她是社会环境的被动受伤害者。她的脆弱和无辜不仅仅通过她的周围环境，也通过她自己的行为举止表现出来。论文以主角 Effi Briest 为例，探讨重要的对读者进行情感牵引的规则，并且分析 Fontane 在本小说中有意识的对读者的情感牵引是如何实现的。
手绘在游艇设计中的应用
Authors: 吴 宗铎 , 沈 伯俞 , 严 谨 , 吴 莉 , 满 庆洋
Published: July 2020

论文论述了将手绘引入到游艇的设计过程中。手绘在游艇的创新设计中起到了关键性的作用，尽管它在初级阶段仅仅是一张草图。利用手绘，当灵感出现时，设计者的创意思维可以快速地留存下来。随后，再补充必要的信息以形成完整的方案。修改工作也可以在手绘图上进行。对于游艇设计来说，手绘提供了一种带来新元素的便捷而轻松的方法。和计算机建模相比，手绘可以在省去复杂计算机操作的同时，记录下大量零散的游艇特征信息，为创意设计提供极大的实用性价值。
关于日语拟声拟态词的汉译方法——以夏目漱石《我是猫》为例
Authors: 滑 姝娅
Published: July 2020

日语拟声拟态词数量繁多，在日语中占有一席之地。而汉语中象声象形词相对较少，这使翻译拟声拟态词变得难上加难。现有研究多围绕日语拟声拟态词的构造方法、语音变化、分类方式、意义特征等展开的，而从拟声拟态词自身的语法特征考察中文译法的研究相对较少，且在一定程度上缺乏统一性。因此，论文从夏目漱石的名作《我是猫》中抽取全部日语拟声拟态词，并统计整理了刘振瀛、于雷、曹曼三人译本中的对应汉译，从词性类别的角度一一进行了比较分析，进而探讨出拟声拟态词的汉译方法。
ANALISA REKAYASA NILAI (VALUE ENGINEER) PADA KONSTRUKSI BANGUNAN RUMAH DINAS PUSKESMAS KARANG JATI BALIKPAPAN
Authors: Mahyuddin Mahyuddin
Published: July 2020

Pelaksanaan suatu proyek sangat bergantung pada penggunaan biaya. Dalam kegiatan suatu proyek akan banyak didapati masalah seperti penggunaan material yang boros, tenaga kerja yang kurang terampil dan waktu penyelesaian proyek yang tidak tepat waktu yang menyebabkan pemborosan biaya. Untuk mendapatkan hasil yang efisien dengan menggunakan metode Rekayasa Nilai (Value Engineering). Rekayasa nilai (Value Engineering) adalah suatu pendekatan terorganisasi dan kreatif yang bertujuan untuk mengadakan pengidentifikasian biaya tidak perlu, yang tidak memberikan kualitas atau kegunaan Dengan menggunakan aplikasi rekayasa nilai yang diterapkan pada pekerjaan konstruksi Bangunan Puskesmas Karang Jati Balikpapan dengan mengganti alternative material awal bata merah dengan bata ringan. Besar penghematan keseluruhan pada pekerjaan dinding yang didapat Rp. 50.280.567 dari biaya awal sebesar Rp. 297.732.062, setelah dilakukan analisis Rekayasa Nilai menjadi Rp. 247.481.470, dengan nilai penghematan sebesar 16,88 %
Sebaran Nyamuk Vektor di Betung Bedarah, Kabupaten Tebo, Provinsi Jambi
Authors: Maloha Maas M , Ratnaningrum Kanti
Published: July 2020

Latar Belakang: Sampai saat ini nyamuk masih menjadi salah satu vektor penyakit pada manusia. Secara geografis, Indonesia merupakan wilayah yang baik sebagai lokasi perkembangbiakan nyamuk. Beberapa penyakit yang disebabkan gigitan nyamuk masih terjadi di Provinsi Jambi, khususnya Kabupaten Tebo. Penelitian ini bertujuan mengetahui sebaran nyamuk di Betung Bedarah, Kabupaten Tebo, Provinsi JambiMetode: Kegiatan merupakan survey lapangan dalam mengidentifikasi sebaran nyamuk di Betung Bedarah, Kabupaten Tebo. Penangkapan nyamuk dilakukan menggunakan metode human landing collection dan resting collection.Hasil: Dari 64 nyamuk yang tertangkap, sebaran nyamuk menujukkan 43,75% merupakan nyamuk Armigeres, 25% nyamuk Anopheles, 17,19% nyamuk Culex, dan 14,06% nyamuk Mansonia. Puncak angka kepadatan nyamuk per orang per jam (MHD) tertinggi pada jam 20.00-21.00 WIB.Kesimpulan: Sebaran nyamuk sebagai vektor penyakit di Betung Bedarah, Kabupaten Tebo tertinggi adalah Anopheles.
Gambaran Status Kesehatan Gigi dan Mulut pada Pasien Prolanis di Puskesmas Kedungmundu
Authors: Soni Zazkia Zita Zhafira , Kusniati Retno , Rakhmawati Ayu Kristin
Published: July 2020

Latar Belakang: Kesehatan gigi dan mulut masih menjadi permasalahan di masyarakat yang perlu diperhatikan. Prevalensi penduduk yang mempunyai masalah gigi dan mulut di Indonesia menurut Riskesdas 2018 sebesar 57,6%. PROLANIS (Program Pengelolaan Penyakit Kronis) merupakan suatu program dengan dua fokus penyakit yaitu Diabetes Melitus dan Hipertensi. Kasus Diabetes Melitus tertinggi di Kota Semarang tahun 2018 ada di Puskesmas Kedungmundu sebanyak 3.165 kasus dan Hipertensi sebanyak 4.417 kasus. Penderita Diabetes Melitus mempunyai beberapa manifestasi oral seperti karies, mulut kering, dan periodontitis. Sedangkan Hipertensi mempunyai manifestasi oral seperti hyperplasia gingival dan xerostomia. Tujuan penelitian ini adalah mendeskripsikan status kesehatan gigi dan mulut pada pasien Prolanis di Puskesmas Kedungmundu.Metode: Jenis penelitian deskriptif dengan pendekatan cross sectional, menggunakan teknik purposive sampling  diperoleh 55 responden.Hasil: Keadaan mahkota gigi karies sebesar 38,6%, akar gigi karies sebesar 34,8%, gingival bleeding atau perdarahan gingiva sebesar 47,8%, poket periodontal 4-5 mm sebesar 75,1%, kehilangan perlekatan yaitu 0-3 mm, tidak ada tanda erosi sebesar 54%, tidak ada lesi mukosa oral sebesar 50,9%, kebutuhan perawatan segera sebesar 72,7%, dan hanya satu pasien yang menggunakan gigi tiruan.Kesimpulan: Pasien Prolanis di Puskesmas Kedungmundu mempunyai status kesehatan gigi dan mulut mahkota dan akar gigi yang karies, terdapat gingival bleeding atau perdarahan gingiva, terdapat poket periodontal dan kehilangan perlekatan, tidak ada tanda erosi gigi dan lesi mukosa oral, kebutuhan perawatan perlu tetapi tidak segera, dan hanya satu pasien yang menggunakan gigi tiruan.
Hubungan Manajemen Performa Kinerja Dosen Terhadap Hasil Belajar Mahasiswa FKG Unimus
Authors: Sholekhah Nur Khamilatusy
Published: July 2020

Latar Belakang: Untuk meningkatkan  mutu pendidikan, seorang pendidik diwajibkan memiliki keterampilan dasar yang baik sebagai penunjang pembelajaran.. Profesi dosen adalah pendidik profesional yang dituntut memiliki kinerja dalam bidang pengajaran dan pendidikan, penelitian serta melakukan pengabdian ke masyarakat secara luas dan mendalam. Penelitian ini bertujuan untuk mengetahui pengaruh performa kinerja dosen terhadap hasil belajar mahasiswa FKG UNIMUS.Metode: Penelitian ini menggunakan jenis penelitian deskriptif kuantitatif dimana kesimpulan ditarik melalui analisis statistik. Populasi dan sampel dalam penelitian ini adalah mahasiswa Program Studi Pendidikan Dokter Gigi UNIMUS angkatan 2017 yang berjumlah 48 mahasiswa. Teknik pengumpulan data yang dilaksanakan dalam penelitian menggunakan metode angket dan metode dokumentasi. Metode analisis data pada penelitian ini menggunakan software SmartPLS versi 2.0.m3 yang dijalankan dengan media komputer.Hasil: Berdasarkan hasil penelitian didapatkan hasil bahwa performa kinerja dosen berpengaruh positif dan signifikan terhadap hasil belajar mahasiswa karena nilai tstatistik lebih besar dari ttabel (tstatistik 14,55 > ttabel 1,66) pada taraf signifikansi 5%.Kesimpulan: terdapat hubungan performa dosen yang dinilai dari 3 dimensi yaitu monitoring umum, pengajaran, dan materi terhadap hasil belajar ujian tertulis mahasiswa Fakultas Kedokteran Gigi Universitas Muhammadiyah Semarang di Blok Keterampilan Belajar dan Komunikasi tahun akademik 2017/2018.
Tingkat Kondisi Fisik Member Senam Aerobik di Sanggar “Gleonov Gym”
Authors: Febriyanti Fery , Jayadi Ika , Wiriawan Oce
Published: July 2020

Senam aerobik merupakan serangkain gerak yang dipilh secara sengaja dengan cara mengikuti irama musik yang juga dipilih sehingga melahirkab ketentuan ritmis, kontiyuitas dan durasi tertentu. Tujuan dari penelitian ini adalah untuk mengetahui tingkat kondisi fisik member senam aerobik di Sanggar Gleonov Gym. Subyek penelitian ini adalah ibu-ibu senam aerobik di Sanggar Glonov Gym yang diambil 15 orang. Metode menggunakan statistik kuantitatif deskriptif, teknik pengumpulan data dilakukan dengan menggunkan tes: daya tahan otot jantung, daya tahan otot lengan, daya tahan otot perut, dan kelentukan. Kesimpulan : (1) Mayoritas  daya tahan otot jantung member senam aerobik di Sanggar Glenonov Gym adalah kurang. Tingkat prosentase daya tahan otot jantung 10% kategori sangat baik, 0% kategori baik, 20% kateegori cukup, 40% kategori kurang, dan 30% kategori kurang sekali. (2) Mayoritas daya tahan otot lengan member senam aerobik di Sanggar Glenonov Gym adalah kurang. Tingkat prosentase daya tahan otot lengan 0% kategori baik sekali, 10% kategori baik, 30% kategori cukup, 40% kategori kurang, dan 20% kategori kurang sekali. (3) Mayoritas daya tahan otot perut member senam aerobik di Sanggar Glenonov Gym adalah cukup. Tingkat prosentase daya tahan otot perut 10% kategori baik sekali, 20% kategori baik, 40% kategori cukup, dan 10% kategori kurang sekali. (4) Mayoritas kelentukan member senam aerobik di Sanggar Glenonov Gym adalah baik sekali. Tingkat prosentase kelentukan 40%  kategori baik sekali, 30% kategori baik, 20% kategori cukup, 0% kategori kurang, dan 10% kategori kurang sekali.
Fenomena dan Dampak Partisipasi Masyarakat dalam Berolahraga di Kawasan Car Free Day (Cfd) di Kota Besar (Studi pada Kota Semarang, Surabaya, Surakarta)
Authors: Darmanto Fery , Akhiruyanto Andry , Setyawati Heny , Suripto Agus Widodo
Published: July 2020

Tujuan penelitian ini adalah mendeskripsikan tentang fenomena kegiatan olahraga yang dilakukan dikawasan CFD (Car Free Day) di Kota besar. Penelitian ini adalah penelitian kualitatif dengan menggunakan pendekatan deskriptif, dengan desain korelasional yang bertujuan menghubungkan dua variabel atau lebih, sedangkan teknik pengumpulan data menggunakan metode observasi, wawancara, pengumpulan dokumen lalu dianalisisi dengan reduksi data, penyajian data dan penarikan kesimpulan. Hasil dan kesimpulan dalam penelitian ini sebagai berikut fenomena yang terjadi di kota besar adalah 80% responden datang ke CFD dengan berkelompok dan membawa peralatan olahraga seperti bola, tali atau sepeda angina dari rumah, 86% responden datang rata-rata 2-3 kali dalam sebulan dan menghabiskan waktu selama 2 jam dikawasan CFD untuk berolahraga dan aktivitas lainnya. Dampak yang terjadi adalah 23% responden merasa senang dan terhibur dengan olahraga di kawasan CFD, sedangkan 72% responden merasa mendapatkan semangat dan motivasi baru sepulang dari olahraga dikawasan CFD dan 5% responden merasakan hal yang biasa saja. Rekomendasi dari penelitian ini adalah untuk pemerintah kota dan kabupaten di Indonesia untuk mengadakan lebih banyak kegiatan CFD di daerahnya, untuk mengurangi dampak polusi kendaraan, meningkatkan kebugaran publik dan menjadi tempat hiburan yang menyenangkan bagi masyarakat.