bluuebunny/crossref_metadata_2025 huggingface dataset:
Global Trends of Treatment for NAFLD from 2012 to 2021: A Bibliometric
and Mapping Analysis
Authors: Song Yuling , Chen Boru , Jiang Lu , Zhao Fangkun , Feng Xiuqin
Published: October 2023

Aim:

The present study aimed to map publication trends and explore research hotspots of treatment for NAFLD study by bibliometric analysis.

Background:

Nonalcoholic fatty liver disease (NAFLD) is a multi-system metabolic disorder involving the liver. Thousands of papers have been published on the treatment of NAFLD, but no comprehensive statistical and intuitive analysis has been made. The present study aimed to map publication trends and explore research hotspots of treatment for NAFLD study by biblio-metric analysis.

Objective:

(1) the pathogenesis of NAFLD and the possible treatment mechanism; (2) preva-lence, risk factors, and traditional therapies for NAFLD; (3) frontier therapies for NAFLD. Method; This paper conducted a bibliometric analysis based on the Web of Science Core Col-lection (WoSCC). The knowledge map was constructed by VOS viewer v.1.6.10 to visualize the annual publication number, the distribution of countries, international collaborations, author productivity, source journals, cited references, and keywords in this field.

Results:

From 2012 to 2021, 2,437 peer-reviewed publications on the treatment of NAFLD were retrieved. China contributed the most publications, while the United States received the most citations. Journal of Hepatology was the most prolific journal in this field. Prof. Rohit Loomba.

Conclusion:

Our study provides a comprehensive and objective analysis of NAFLD treatment that allows researchers to quickly locate research hotspots in a large number of relevant litera-tures. Meanwhile, it may also provide valuable information for researchers looking for potential partners and institutions.
Network Pharmacological Analysis and Experimental Validation of the
Effects of Silybin on Proliferation, Migration, and Immunotherapy of
Papillary Thyroid Cancer
Authors: Xie Wenjun , Li Huashui , Lin Qiang , Ke Naizhuo
Published: October 2023

Aim:

The study aimed to use network pharmacology research and in vitro experiments
to investigate the material basis and molecular mechanisms of silybin in the treatment of papillary
thyroid carcinoma.

Background:

Papillary thyroid cancer (PTC) has a decent prognosis; however, recurrence and metastasis
are the leading causes of death in patients with PTC. A key research focus in thyroid cancer
treatment is the inhibition of PTC proliferation, invasion, and migration. Silybin, the major active
element in the traditional Chinese herb silymarin, has been used to treat a range of diseases, including
cancer, but no study has been undertaken to determine whether it can help prevent PTC.

Objective:

In this study, we attempted to determine through network pharmacology and in vitro
experiments if silybin inhibits the development of papillary thyroid cancer by inhibiting cell cycle
and invasive migration.

Methods:

To predict the probable targets and underlying mechanisms of silybin against PTC, a
network pharmacology research was performed. In vitro experiments were conducted to further
evaluate silybin's anti-cancer properties and priority targets against PTC.

Results:

The datasets revealed a total of 489 silybin targets acting on PTC, and functional enrichment
analysis suggested that the target genes were enriched in functions and pathways related to
PTC development, invasion, migration, and immunotherapy. By constructing these target PPI networks,
the seven hub genes, fibronectin 1 (FN1), tissue inhibitor of metalloproteinases 1 (TIMP1),
N-cadherin (CDH2), collagen type III alpha 1 chain (COL3A1), cyclin D1 (CCND1), AP-1 transcription
factor subunit (JUN), and hepatocyte growth factor receptor (MET) were found. These
hub genes were determined to be highly linked to a worse clinicopathological form, a higher risk of
metastatic recurrence, and a worse prognosis of PTC. The common immunological checkpoint
gene expression levels were positively correlated with the expression levels of the hub genes. Silybin
decreased the proliferative and metastatic capacity of PTC cells, according to in vitro investigations.
When PTC was treated with silybin, the FN1/AKT signaling pathway was blocked,
CCND1 expression was reduced, and CDH2, Vimentin, Snail, Slug and PD-L1 expressions were
dramatically reduced, while E-cadherin expression was significantly elevated.

Conclusion:

These findings provide preliminary evidence that silybin inhibits PTC cell proliferation,
metastasis, and invasion by altering the FN1/AKT signaling pathway and inhibiting the EMT
process. Silybin can reverse immunosuppression in papillary thyroid cancer by affecting immunological
checkpoint gene expression levels. These studies provide a theoretical and experimental
scientific basis for the potential anticancer effects of silybin on PTC.
Seroprevalence of SARS-CoV-2 in Niger State: Pilot Cross-Sectional Study
Authors: Majiya Hussaini , Aliyu-Paiko Mohammed , Balogu Vincent Tochukwu , Musa Dickson Achimugu , Salihu Ibrahim Maikudi , Kawu Abdullahi Abubakar , Bashir Ishaku Yakubu , Sani Aishat Rabiu , Baba John , Muhammad Amina Tako , Jibril Fatimah Ladidi , Bala Ezekiel , Obaje Nuhu George , Aliyu Yahaya Badeggi , Muhammad Ramatu Gogo , Mohammed Hadiza , Gimba Usman Naji , Uthman Abduljelili , Liman Hadiza Muhammad , Alhaji Sule Alfa , James Joseph Kolo , Makusidi Muhammad Muhammad , Isah Mohammed Danasabe , Abdullahi Ibrahim , Ndagi Umar , Waziri Bala , Bisallah Chindo Ibrahim , Dadi-Mamud Naomi John , Ibrahim Kolo , Adamu Abu Kasim
Published: October 2023

Background

The COVID-19 pandemic caused by SARS-CoV-2 is causing ongoing human and socioeconomic losses.

Objective

To know how far the virus has spread in Niger State, Nigeria, a pilot study was carried out to determine the SARS-CoV-2 seroprevalence, patterns, dynamics, and risk factors in the state.

Methods

A cross-sectional study design and clustered, stratified random sampling strategy were used to select 185 test participants across the state. SARS-CoV-2 IgG and IgM rapid test kits (colloidal gold immunochromatography lateral flow system) were used to determine the presence or absence of antibodies to the virus in the blood of sampled participants across Niger State from June 26 to 30, 2020. The test kits were validated using the blood samples of some of the Nigeria Center for Disease Control–confirmed positive and negative COVID-19 cases in the state. SARS-CoV-2 IgG and IgM test results were entered into the Epi Info questionnaire administered simultaneously with each test. Epi Info was then used to calculate the arithmetic mean and percentage, odds ratio, χ2 statistic, and regression at a 95% CI of the data generated.

Results

The seroprevalence of SARS-CoV-2 in Niger State was found to be 25.4% (47/185) and 2.2% (4/185) for the positive IgG and IgM results, respectively. Seroprevalence among age groups, genders, and occupations varied widely. The COVID-19 asymptomatic rate in the state was found to be 46.8% (22/47). The risk analyses showed that the chances of infection are almost the same for both urban and rural dwellers in the state. However, health care workers, those who experienced flulike symptoms, and those who had contact with a person who traveled out of Nigeria in the last 6 months (February to June 2020) were at double the risk of being infected with the virus. More than half (101/185, 54.6%) of the participants in this study did not practice social distancing at any time since the pandemic started. Participants’ knowledge, attitudes, and practices regarding COVID-19 are also discussed.

Conclusions

The observed Niger State SARS-CoV-2 seroprevalence and infection patterns meansuggest that the virus has widely spread, far more SARS-CoV-2 infections have occurred than the reported cases, and there is a high asymptomatic COVID-19 rate across the state.
Older Adults’ Trust and Distrust in COVID-19 Public Health Information: Qualitative Critical Incident Study
Authors: Shiroma Kristina , Zimmerman Tara , Xie Bo , Fleischmann Kenneth R , Rich Kate , Lee Min Kyung , Verma Nitin , Jia Chenyan
Published: October 2023

Background

The COVID-19 infodemic has imposed a disproportionate burden on older adults who face increased challenges in accessing and assessing public health information, but little is known about factors influencing older adults’ trust in public health information during COVID-19.

Objective

This study aims to identify sources that older adults turn to for trusted COVID-19 public health information and factors that influence their trust. In addition, we explore the relationship between public health information sources and trust factors.

Methods

Adults aged 65 years or older (N=30; mean age 71.6, SD 5.57; range 65-84 years) were recruited using Prime Panels. Semistructured phone interviews, guided by critical incident technique, were conducted in October and November 2020. Participants were asked about their sources of COVID-19 public health information, the trustworthiness of that information, and factors influencing their trust. Interview data were examined with thematic analysis.

Results

Mass media, known individuals, and the internet were the older adults’ main sources for COVID-19 public health information. Although they used social media for entertainment and personal communication, the older adults actively avoided accessing or sharing COVID-19 information on social media. Factors influencing their trust in COVID-19 public health information included confirmation bias, personal research, resigned acceptance, and personal relevance.

Conclusions

These findings shed light on older adults’ use of information sources and their criteria for evaluating the trustworthiness of public health information during a pandemic. They have implications for the future development of effective public health communication, policies, and interventions for older adults during health crises.
Integrating Clinical Decision Support Into Electronic Health Record Systems Using a Novel Platform (EvidencePoint): Developmental Study (Preprint)
Authors: Solomon Jeffrey , Dauber-Decker Katherine , Richardson Safiya , Levy Sera , Khan Sundas , Coleman Benjamin , Persaud Rupert , Chelico John , King D'Arcy , Spyropoulos Alex , McGinn Thomas
Published: October 2023

BACKGROUND

Through our work, we have demonstrated how clinical decision support (CDS) tools integrated into the electronic health record (EHR) assist providers in adopting evidence-based practices. This requires confronting technical challenges that result from relying on the EHR as the foundation for tool development; for example, the individual CDS tools need to be built independently for each different EHR.

OBJECTIVE

The objective of our research was to build and implement an EHR-agnostic platform for integrating CDS tools, which would remove the technical constraints inherent in relying on the EHR as the foundation and enable a single set of CDS tools that can work with any EHR.

METHODS

We developed EvidencePoint, a novel, cloud-based, EHR-agnostic CDS platform, and we will describe the development of EvidencePoint and the deployment of its initial CDS tools, which include EHR-integrated applications for clinical use cases such as prediction of hospitalization survival for patients with COVID-19, venous thromboembolism prophylaxis, and pulmonary embolism diagnosis.

RESULTS

The results below highlight the adoption of the CDS tools, the International Medical Prevention Registry on Venous Thromboembolism-D-Dimer, the Wells’ criteria, and the Northwell COVID-19 Survival (NOCOS), following development, usability testing, and implementation. The International Medical Prevention Registry on Venous Thromboembolism-D-Dimer CDS was used in 5249 patients at the 2 clinical intervention sites. The intervention group tool adoption was 77.8% (4083/5249 possible uses). For the NOCOS tool, which was designed to assist with triaging patients with COVID-19 for hospital admission in the event of constrained hospital resources, the worst-case resourcing scenario never materialized and triaging was never required. As a result, the NOCOS tool was not frequently used, though the EvidencePoint platform’s flexibility and customizability enabled the tool to be developed and deployed rapidly under the emergency conditions of the pandemic. Adoption rates for the Wells’ criteria tool will be reported in a future publication.

CONCLUSIONS

The EvidencePoint system successfully demonstrated that a flexible, user-friendly platform for hosting CDS tools outside of a specific EHR is feasible. The forthcoming results of our outcomes analyses will demonstrate the adoption rate of EvidencePoint tools as well as the impact of behavioral economics “nudges” on the adoption rate. Due to the EHR-agnostic nature of EvidencePoint, the development process for additional forms of CDS will be simpler than traditional and cumbersome IT integration approaches and will benefit from the capabilities provided by the core system of EvidencePoint.
Remote Perimetry in a Virtual Reality Metaverse Environment for Out-of-Hospital Functional Eye Screening Compared Against the Gold Standard Humphrey Visual Fields Perimeter: Proof-of-Concept Pilot Study (Preprint)
Authors: Wong Kang-An , Ang Bryan Chin Hou , Gunasekeran Dinesh Visva , Husain Rahat , Boon Joewee , Vikneson Krishna , Tan Zyna Pei Qi , Tan Gavin Siew Wei , Wong Tien Yin , Agrawal Rupesh
Published: October 2023

BACKGROUND

The growing global burden of visual impairment necessitates better population eye screening for early detection of eye diseases. However, accessibility to testing is often limited and centralized at in-hospital settings. Furthermore, many eye screening programs were disrupted by the COVID-19 pandemic, presenting an urgent need for out-of-hospital solutions.

OBJECTIVE

This study investigates the performance of a novel remote perimetry application designed in a virtual reality metaverse environment to enable functional testing in community-based and primary care settings.

METHODS

This was a prospective observational study investigating the performance of a novel remote perimetry solution in comparison with the gold standard Humphrey visual field (HVF) perimeter. Subjects received a comprehensive ophthalmologic assessment, HVF perimetry, and remote perimetry testing. The primary outcome measure was the agreement in the classification of overall perimetry result normality by the HVF (Swedish interactive threshold algorithm–fast) and testing with the novel algorithm. Secondary outcome measures included concordance of individual testing points and perimetry topographic maps.

RESULTS

We recruited 10 subjects with an average age of 59.6 (range 28-81) years. Of these, 7 (70%) were male and 3 (30%) were female. The agreement in the classification of overall perimetry results was high (9/10, 90%). The pointwise concordance in the automated classification of individual test points was 83.3% (8.2%; range 75%-100%). In addition, there was good perimetry topographic concordance with the HVF in all subjects.

CONCLUSIONS

Remote perimetry in a metaverse environment had good concordance with gold standard perimetry using the HVF and could potentially avail functional eye screening in out-of-hospital settings.
Inhibitory Control Training for Anxiety and Math Achievement in Primary School Children: Protocol for a Proof-of-Concept Study (Preprint)
Authors: Edwards Elizabeth , Chu Khanh Linh , Carroll Annemaree
Published: October 2023

BACKGROUND

Cognitive control training (CCT) has shown potential to reduce emotional vulnerability in adults and adolescents. However, there is scant literature testing the efficacy of CCT for the reduction of anxiety and transferring the effects to educational outcomes in children. Building on the evidence that a greater ability to suppress a prepotent response (inhibitory control) is associated with higher math achievement in children, it is plausible that training inhibitory processes using a CCT paradigm may be beneficial for reducing anxiety, improving inhibitory control, and in turn increasing math achievement.

OBJECTIVE

This proof-of-concept study aims to investigate the efficacy of 15 sessions of inhibitory control training for reduction in anxiety and improvement in math achievement in primary school children.

METHODS

We will use a 2 (group: CCT, adaptive Go/No-Go vs active control, low-load task) multiplied by 4 (time: pre- vs posttraining vs 1-month vs 3-month follow-up) randomized design in a nonselected sample of 100 children aged 8-10 years. Both groups will complete 10 minutes of daily training for 3 weeks at school. The dependent variables will be anxiety and correlates (Spence Children’s Anxiety Scale, Penn State Worry Questionnaire for Children, Revised Children’s Anxiety and Depression Scale, Child Response Style Questionnaire, and Modified Abbreviated Math Anxiety Scale), inhibitory control (Go/No-Go task), shifting (color-shape shifting task), updating (n-back task), and math achievement (Applied Problems, Calculation, and Math Facts Fluency subtests from the Woodcock-Johnson IV Tests of Achievement).

RESULTS

We opened enrollment in September 2023. The initial results are expected to be published in late 2024. We predict that children in the CCT group will show a reduction in emotional symptoms; improvements in inhibition, shifting, and updating performance; and advances in math achievement from pre- to posttraining, and that these effects will be maintained at 1- and 3-month follow-ups, compared to children in the active control group.

CONCLUSIONS

The CCT paradigm used in our study will provide a greater understanding of the emotional and cognitive transfer effects on children and inform future work. Specifically, the findings will advance the knowledge of deploying inhibitory control training with children and provide valuable insights into its use for reducing anxiety and advancing math achievement.

CLINICALTRIAL

Open Science Framework ofs.io/de2qa; https://doi.org/10.17605/OSF.IO/DE2QA

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/52929
Designing for Improved Patient Experiences in Home Dialysis: Usability and User Experience Findings From User-Based Evaluation Study With Patients With Chronic Conditions (Preprint)
Authors: Aspelund Anna , Valkonen Paula , Viitanen Johanna , Rauta Virpi
Published: October 2023

BACKGROUND

Chronic kidney disease affects 10% of the population worldwide, and the number of patients receiving treatment for end-stage kidney disease is forecasted to increase. Therefore, there is a pressing need for innovative digital solutions that increase the efficiency of care and improve patients’ quality of life. The aim of the eHealth in Home Dialysis project is to create a novel eHealth solution, called eC4Me, to facilitate predialysis and home dialysis care for patients with chronic kidney disease.

OBJECTIVE

Our study aimed to evaluate the usability, user experience (UX), and patient experience (PX) of the first version of the eC4Me solution.

METHODS

We used a user-based evaluation approach involving usability testing, questionnaire, and interview methods. The test sessions were conducted remotely with 10 patients with chronic kidney disease, 5 of whom had used the solution in their home environment before the tests, while the rest were using it for the first time. Thematic analysis was used to analyze user test and questionnaire data, and descriptive statistics were calculated for the UMUX (Usability Metric for User Experience) scores.

RESULTS

Most usability problems were related to navigation, the use of terminology, and the presentation of health-related data. Despite usability challenges, UMUX ratings of the solution were positive overall. The results showed noteworthy variation in the expected benefits and perceived effort of using the solution. From a PX perspective, it is important that the solution supports patients’ own health-related goals and fits with the needs of their everyday lives with the disease.

CONCLUSIONS

A user-based evaluation is a useful and necessary part of the eHealth solution development process. Our study findings can be used to improve the usability and UX of the evaluated eC4Me solution. Patients should be actively involved in the solution development process when specifying what information is relevant for them. Traditional usability tests complemented with questionnaire and interview methods can serve as a meaningful methodological approach for gaining insight not only into usability but also into UX- and PX-related aspects of digital health solutions.
Exploring student perspectives and experiences of online opportunities for virtual caring skills development: A sequential explanatory mixed-methods study (Preprint)
Authors: Nowell Lorelli , Dolan Sara , Johnston Sonja , Jacobsen Michele , Lorenzetti Diane , Oddone Paolucci Elizabeth
Published: October 2023

BACKGROUND

Caring professions students require skills and competencies to proficiently use information technologies for providing high-quality and effective care. However, there is a gap in exploring the perceptions and experiences of students in developing virtual caring skills within online environments.

OBJECTIVE

Our objective was to to explore caring professions students experiences and perceptions of online learning opportunities for developing their virtual caring skills and competencies.

METHODS

A sequential explanatory mixed-methods approach, integrating both a cross-sectional survey and individual interviews, was employed to better understand caring professional students' online learning experiences with developing virtual caring skills and competencies.

RESULTS

A total of 93 survey and 9 interview participants were drawn from various faculties, including students from Education, Nursing, Medicine, and Allied Health. These participants identified barriers, facilitators, principles, and skills related to learning about and delivering virtual care, including teaching methods and educational technologies.

CONCLUSIONS

This study contributes to the growing body of educational research on virtual caring skills by offering student insights and suggestions for improved teaching and learning strategies in caring professions’ programs.
A Study on the Teaching Methodologies of College English Writing
Authors: WANG Dong
Published: October 2023

Through research on the compositions written by the surveyed university students from different majors in English final examination, it can be concluded that more than half of the students need to take great efforts to improve their English writing level. The problems existing in writing is closely related to the deficiency in the input of English reading. According to Krashen’s “i+1” theory, university students need to greatly increase their input of English reading and it should begin with reading the materials that surpass their present level. The best way to do so is reading the great works in British and American literature.
Safety of Herbal Medicines on Liver Function in Functional Dyspepsia Patients: A Single-Center Retrospective Study
Authors: Han Aram , Keum Chang-Yul , Yoon Chae-Rim , Choi Su-Hyun , Jeong Dahee , Jeong Nahyun , Jeong Hae-in , Ha Na-Yeon , Kim Jinsung
Published: October 2023

Objectives: This study analyzed laboratory serum data results before and after patients took herbal medicine to confirm the clinical safety of herbal medicine. In addition, in the event of liver damage, the case was analyzed to confirm the characteristics of liver damage and the possibility of liver damage caused by herbal medicine.Methods: A retrospective chart review of the effects of herbal medicine on liver function in patients diagnosed with functional dyspepsia was conducted. The electronic medical records of 128 patients in a single hospital were reviewed.Results: The statistical analysis revealed a statistically significant decrease in liver function-related laboratory serum data after taking herbal medicine (p<0.05). In addition, among 128 patients, there were two cases of drug-induced liver injury (DILI) (1.56%).Conclusion: Taking herbal medicine prescribed by experts does not significantly affect liver function in patients with functional dyspepsia. Rather, the liver levels of the subjects showed a significant decrease after taking herbal medicine. To support these results, further large-scale multicenter prospective studies are necessary.
A Case Study of Buerger’s Disease of Soeumin with Lower Extremity Coldness
Authors: Choi Song , Jeong Su-min , Son So-eun , Byun Jeong-won , Choi Sae-rom , Park Hye-sun
Published: October 2023

Objectives: This study investigated the effects of Korean medicine treatments on Buerger’s disease.Methods: From December 27, 2022, to January 16, 2023, we treated Soeumin patients with Buerger’s disease admitted to a hospital specializing in Korean medicine. The patient’s symptoms included feelings of coldness in the lower extremities, feelings of dullness, and stabbing pain. For treatment, Korean medicine treatments, such as acupuncture, moxibustion, and herbal medications (Sogyeonghwalhyeol-tang granules and Gwangyebujaijung-tang-gami) were administered. The patient’s improvement was evaluated using the numerical rating scale (NRS) every day. Lower extremity and foot temperatures were evaluated using digital infrared thermal imaging (DITI).Results: Through the treatment regimen, the patient’s NRS scores decreased, and lower extremity and foot temperatures increased.Conclusions: Korean medicine treatments for cold lower extremities, feelings of dullness, and stabbing pain caused by Buerger’s disease are potentially effective.
A Case Report of Korean Medicine Treatment Including Samchulgunbi-tang-gagambang in a Patient with Vestibular Neuritis
Authors: Park Ye-seul , Kim Jeong-hui , Song Ju-yeon , Yoo Ho-ryong , Seol In-chan , Kim Yoon-sik
Published: October 2023

Background: Vestibular neuritis is a common cause of acute unilateral peripheral vestibulopathy. Vestibular neuritis is the second most common disease among patients with dizziness. Clinical symptoms of vestibular neuritis include the sudden onset of vertigo with spontaneous nystagmus, unsteady gait, nausea, and vomiting that last from days to weeks. However, even after the vertigo disappears, difficulty maintaining balance while walking may persist for weeks to months. Antihistamines, serotonin receptor blockers, and benzodiazepine vestibular suppressants are widely used as symptomatic treatments to reduce the severity of symptoms that occur in the acute phase.Case Summary: A patient diagnosed with acute vestibular neuritis was treated with acupuncture, moxibustion, and herbal medicine. We used the visual analog scale (VAS) to assess each symptom and the vertigo score to observe the effect of treatment. After treatment, the VAS scores for each symptom and the vertigo score decreased, and the severity of nystagmus was reduced.Conclusion: This study suggests that Korean medicine treatments, including Samchulgunbi-tang-gagam, could be effective in improving the clinical symptoms of vestibular neuritis.
Long-Term Follow-up of Pancreatic Cancer Patients with Lung Metastasis Using Integrated Cancer Treatment: A Case Report
Authors: Oh Yoona , Park Kyung-Dug , Jung, Yu-jin , Kim Jisoo , Jeong Beom-Jin , Bang Sunhwi
Published: October 2023

Objective: This long-term case report details a case of pancreatic cancer with lung metastasis suppressed by integrative cancer medicine (IMT).Methods: A 64-year-old woman diagnosed with pancreatic cancer visited a Korean medicine hospital complaining about the side effects of chemotherapy for lung metastasis. She received IMT involving Korean traditional medicine and Western immunotherapy from May 2017 to June 2023. Tumor dimensions were assessed through computed tomography (CT) and positron-emission tomography/CT scans, while tumor markers and safety were monitored by laboratory tests.Results: IMT suppressed the progression of cancer, as observed by imaging and laboratory tests. The patient achieved 5-year survival, even after discontinuing chemotherapy.Conclusion: This case presents a potential therapeutic alternative for patients who are ineligible for chemotherapy or surgical interventions.
LITIGÂNCIA CLIMÁTICA BRASILEIRA
Authors: Lauermann Lazzaretti Luisa , Winter de Carvalho Délton
Published: October 2023

Os relatórios do IPCC são uníssonos em prever que haverá um aumentos dos impactos das mudanças climáticas, corroborando que a atividade antrópica, principalmente pela queima dos combustíveis fósseis tem aquecido a terra desde a Primeira Revolução Industrial. Diante desse cenário vários aspectos da vida humana e do meio ambiente se modificaram: acidificação e aumento do nível dos oceanos, extinção de várias espécies, derretimento de geleiras, etc. Igualmente, essas alterações causam impactos negativos nos direitos humanos como o abastecimento de alimentos, água potável, saúde e moradia. No Brasil, esse cenário é reiterado pelo descaso com as políticas ambientais e climáticas que tem fomentado ainda mais esse ciclo de destruição em uma verdadeira emergência climática. Sob esse contexto a litigância climática brasileira tem se sobressaído, visto que é caminho fundamental para centrar a discussão dos diversos grupos de interesse em uma política voltada para o meio ambiente equilibrado para a presente e futuras gerações. Esse artigo realizou um estudo de caso da Ação Civil Pública Climática interposta pelo Instituto de Estudos amazônicos (IEA) contra a União. Para tanto, o método escolhido para essa pesquisa foi o dedutivo, sendo desenvolvido a partir da pesquisa bibliográfica descritiva, através de publicações sobre os assuntos mudanças e litigância climáticas em artigos científicos publicados nas principais bases de dados e relevantes livros de doutrina. Espera-se que no Brasil essa Ação Civil Climática incentive a discussão entre a sociedade civil e os grupos de interesse desse tema tão urgente bem como a propositura de novas ações climáticas.
Can team communication obscure severe usability problems?
Authors: Geszten Dalma , Hámornik Balázs Péter
Published: October 2023

Team communication is a significant topic of study in the psychological literature, but it is a less researched area in relation to software usability. In this article, as part of a larger research project, we investigated team communication to explore the relationship between usability problems and team communication patterns. The research question was examined in two laboratory experiments as part of a collaborative software evaluation process. For sequential analysis of team communication transcripts, we created a custom code system based on previous literature. The results confirm that teams that experience special types of usability problem show different communicational patterns from teams that experience no such problems. The results also show high reliability of the new code system. Further research is needed to explore the relationship between usability problems and team communication patterns in different settings.
Self-protective versus utilitarian autonomous vehicles
Authors: Laki Beáta
Published: October 2023

The following examination focuses on the moral dilemmas surrounding the comparison of self-protective and utilitarian autonomous vehicles. These vehicles can be programmed to prioritize the safety of passengers in an accident or prioritize the greater good to save more lives. The essay will explore various ethical questions such as evaluating the numbers game approach, analyzing the principles of beneficence correlated with social inequality, and interpreting the principle of autonomy in the context of autonomous vehicles. Additionally, the examination will consider the harm–benefit ratio. In the sense of methods, this analysis uses the classical issues in a new way and provides recommendations for decision-makers to consider.
Salinity Management in the World’s Most Saline Dam Reservoir: The Gotvand Reservoir, Iran
Authors: Amiri Siamak , Mazaheri Mehdi , Naderkhanloo Vahid , Samani Jamal Mohammad Vali , Ghadimi Sahand , Haghighi Ali Torabi , Noori Roohollah
Published: October 2023

The Gotvand dam was built on the most important Iranian river to support
a number of populated cities with freshwater, provide irrigation water
for million hectares of fertile farmlands, and meet water demand for the
country’s hub industrial zones. This dam is known as one of the worst
engineering failures in Iran’s history because its impoundment submerged
the enormous salty unit of Gachsaran evaporite formation (GEF)
outcropped in the reservoir, leading to reservoir water salinization in
deep layers up to several times greater than that of in the high-seas.
Given the failed practical application of direct intervention strategies
to control the salinity crisis, we suggested a low-cost salinity
management strategy based on the reservoir operation to mitigate the dam
outlet salinity and preserve the downstream environment from the
salinity hazards. The three-dimensional MIKE3 model, was run to
calculate the GEF dissolution rate, accumulated salt in the reservoir,
and the dam outlet salinity. Then, we ran the model considering
different outlet salinity levels to explore the best reservoir operation
strategy to prohibit the accumulated salt in the reservoir and keep the
safe salinity for downstream irrigation-use. Simulation results
suggested that the GEF dissolution rate varied from 0.5 to 7 cm/hr,
mainly due to incremental submergence of the GEF during multi-stage
impoundment of the reservoir. Considering the final dissolution rate of
0.5 cm/hr and inlet salinity from the upstreams, salt accumulation
inside the reservoir can be gradually prevented by setting the outlet
salinity to its maximum historical downstream level, i.e., 1400
µmhos/cm.
Analisis penyajian materi kitab An-Nahwu Al-Wadhih berdasarkan teori mackey
Authors: Amelya Asy Syifa Reza , Tatang Tatang ,   Universitas Pendidikan Indonesia, Supriadi Rinaldi ,   Universitas Pendidikan Indonesia
Published: October 2023

Analysis of material presentation is an activity in determining the validity and suitability of a textbook for educational institutions. In essence, textbooks are one of the factors that support the success of learning. However, another fact was found that textbooks can also be a factor causing poor learning progress. This study aims to provide an overview for educational institutions related to the textbooks studied which can be used as a reference for selecting textbooks. This research uses a qualitative approach with descriptive research type. The object of research is the book Nahwu Wadhih. Data collection techniques were carried out using library research and documentation. Data analysis was carried out using content analysis techniques. Based on the results of this study, from the selection aspect of the book Nahwu Wadhih it aims to familiarize beginners in learning Arabic through an effective model, it is common for educational institutions in Indonesia to complete learning the book Nahwu Wadih every volume for 1 academic year. Judging from the aspect of gradation, the book Nahwu Wadhih uses Rotary Gradation, the type of linguistic gradation is grammatical gradation. Judging from the presentation aspect, this book can be taught by teachers using all existing procedures. Judging from the repetition aspect, this book contains various tests in each chapter. Selection of inappropriate textbooks can cause difficulties for students and teachers. This study has limitations in the literature review because there are few studies using the same subject. For future researchers, it is advisable to carry out an analysis based on other theories as well because there is a possibility that this problem will change. Keywords: textbooks, nahwu wadhih, mackey theory
Use of E-Comic media through canva to increase the Maharah Kitabah
Authors:   Pendidikan Bahasa Arab, Universitas Pendidikan Indonesia, Khalis Salsabila , Sopian Asep ,   Pendidikan Bahasa Arab, Universitas Pendidikan Indonesia
Published: October 2023

Every language skill must have its disadvantages and advantages, as well as writing skills (Maharah Kitabah). Based on the results of observations, there are difficulties in writing skills, namely different backgrounds When attending elementary school, lack of practice and uninteresting material taught by educators to students from the description above shows that there is a need for interesting media to increase enthusiasm for learning in students in writing. One media that can increase students' enthusiasm in writing skills is e-comic. E-comic is a digital comic that is used to convey information about the field of knowledge excitingly and entertainingly, besides the use of e-comics are more practical and can be opened anywhere and anytime as long as they have a file or access link; e-comic is also an attraction for students so that it can help in learning Arabic, especially in maharah kitabah. The research was conducted at SMP Daarut Tauhiid Bandung in class VII, which aimed to determine whether e-comic media was influential in improving maharah kitabah. This study used a quantitative approach with a quasi-experimental design in the form of a Non-Equivalent Control Group Design, which was divided into two research groups: a control group and an experimental group. Data is taken using tests in the form of pretest and post-test. The results showed that e-comic media using Canva was influential in increasing Maharah kitabah with an increase of 23.5; besides that, it was strengthened by a signification value of 0.00, meaning there is a difference in student learning outcomes. This research is expected to be able to use e-comic as one of the supporting media for learning Arabic, especially in Maharah Kitabah Keywords: E-comic, Canva, Maharah kitabah
PENGARUH SUPLEMENTASI MINERAL MIKRO ORGANIK ZN DAN CU TERHADAP KUALITAS FISIK SUSU KAMBING JAWARANDU DI MULIA FARM
Authors: Rahman Fikkri Alfian , Husni Ali , Fathul Farida , Wanniatie Veronica
Published: October 2023

Penelitian ini bertujuan untuk mengetahui pengaruh dan pemberian dosis terbaik suplementasi mineral mikro organik terhadap kualitas fisik susu kambing Jawarandu. Penelitian ini dilaksanakan pada April 2022 di Mulia Farm, Desa Sukabanjar, Kec. Gedong Tataan, Kab. Pesawaran dan di lanjutkan dengan analisa sampel susu di Laboratorium Produksi Ternak, Jurusan Peternakan, Fakultas Pertanian, Universitas Lampung. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) yang terdiri dari 4 perlakuan dengan 3 ulangan. Perlakuan yang diberikan yaitu, R0: Ransum Basal; R1: Ransum Basal + (Zn 20 ppm, Cu 5ppm); R2: Ransum Basal + (Zn 40 ppm, Cu 10ppm); dan R3: Ransum Basal + (Zn- 60 ppm, Cu 15ppm). Peubah yang diamati meliputi berat jenis susu, pH susu, derajat keasaman (°SH), uji alkohol, dan uji didih. Suplementasi  mineral mikro organik berupa Zn-Lysinat 20 ppm, 40 ppm, dan 60 ppm, dan Cu-Lysinat 5 ppm, 10 ppm, dan 15 ppm  menunjukkan hasil yang tidak berpengaruh nyata (P>0,05) terhadap berat jenis susu (1.029—1.031),  pH susu (6.11—6.23), derajat keasaman (8.87—9.60SH), uji alkohol (positif), dan uji didih (negatif) susu kambing Jawarandu.  Suplementasi  mineral mikro organik Zn dan Cu pada level berbeda tidak memberi pengaruh terhadap kualitas fisik baik berat jenis, pH, derajat keasaman, uji alkohol, maupun uji didih susu kambing Jawarandu.
Institutional Space of State Cultural Policy in Russian Society
Authors:   Russian State Social University, Kamenets Alexander V. , Marzoeva Angelika V. ,   Russian State Social University
Published: October 2023

The article examines the problems of the participation of the state and social institutions in the cultural life of Russian society. The main resources of the relevant state cultural policy, which include both state and civil structures, are analyzed. The levels of social interaction between cultural policy and society – micro-, meso-, macro- and mega-level – are highlighted for the study. The main priorities of the activities of state cultural insti-tutions in accordance with the main tasks of the state cultural policy are highlighted, the main promising direc-tions for the formation of an institutional space for interaction between the existing system of cultural services and the population, the need to overcome the existing self-exclusion of state structures from influencing the cultural activity of the population are considered. The proposed solutions for further improvement of the state cultural policy in this context may be of interest to a wide range of specialists in the field of culture and art.
Technological Potential of Social Design: On the Nature of Socio-Historical Dynamics
Authors:   Ural State University of Economics, Lysenko Valery V. , Kormiltseva Elena G. ,   Ural State University of Economics, Kuznetsov Alexander Yu. ,   Ural Federal University
Published: October 2023

The article explores the possibility of a consistent view of the boundaries of arbitrary interference in the objec-tive processes of social development. The materialistic understanding of history, which denies subjective and, moreover, transcendental factors, includes the theory of the revolutionary transformation of society. The change of formations does not occur before the necessary conditions and prerequisites ripen. Meanwhile, revolutions (“locomotives of history”) and, in general, the “living creativity of the masses” are understood as legitimate mechanisms of development. The future is inevitable, but it requires a lot of directed efforts. The automatism of what is happening is always open to arbitrary action. Being defines consciousness, but it never “comes true” without it. The text suggests a direction of thinking that equalizes their rights to the socio-historical reality. From a certain angle, the following considerations can be deemed a general theoretical and partly methodological preface to the next actualization of well-known subjects, including the role of the individual in history.
Interaction of Government and Society in the Formation of the State Scientific and Technical Policy of the Russian Federation in Modern Conditions: System-Dynamic Approach
Authors:   State University of Management, Gusarov Andrey S.
Published: October 2023

The content of this article is the use of a system-dynamic approach as a tool for studying the interaction be-tween government and society in the formation and development of the state scientific and technological policy of the Russian Federation. Events taking place in the modern world, associated with attempts to isolate and impose sanctions on the part of a number of Western European countries and the American side, including in the scientific and technological sphere, as well as the formation of a negative image of Russia in the interna-tional political arena, have prompted changes and revision of the previously adopted educational system based on the Bologna system of education. At the present stage of development of the political system, we can observe the process of formation of a sovereign and independent state scientific and technological policy. Practical experience, combined with the theoretical knowledge possessed by experts, contributes to the for-mation and implementation of an effective public policy in this area that takes into account the modern realities. The advantages of using a systemic dynamic approach as a research tool are its coverage and consideration of modern realities in the study of the formation of state science and technology policy. The use of a system-dynamic approach allows us to identify a number of problems and features, as well as build ways to solve them, based on the analysis carried out within the framework of the formation of the state scientific and tech-nical policy of the Russian Federation.
Resource Centers as a Tool of State Support for Socially Oriented Non-Profit Organizations (On the Example of the City of Moscow)
Authors:   State University of Management, Polyakov Mikhail B. , Bikmanova Adilya K. ,   State University of Management, Khabelashvili Anna ,   State University of Management
Published: October 2023

The study is intended to raise the problem of how to analyze the activities of NPO resource centers as one of the main state support tools for socially oriented non-profit organizations as providers of main social services in the city of Moscow. As part of the conducted research, the main directions of work of the resource center of NPOs in Moscow on the issues of property, information, consulting and educational support of socially oriented organizations of the city were considered. The presented results make it possible to identify the best practices in the organization of state support for SONPOs in the conditions of the economic crisis and development of the social sphere in the city of Moscow. The conducted analysis of the activities of the Resource Center of NPOs in the city of Moscow allowed to systematize the work experience of the State Budgetary Institution of Moscow “Moscow House of Public Organizations” in the field of interaction and support of socially oriented projects.
Finding Ludemes in Modern Board Games: Analyzing the Top Number One Games of Board Game Geek
Authors: Sousa Micael
Published: October 2023

The first profound ludemic studies are being done at the moment. Some projects are exploring the ludemic approach in video games and historic games. However, contemporary games known as modern board games are still underexplored. In this paper, the number one games, according to Board Game Geek since 2000, are analyzed according to a systemic approach. The authors propose exploring the game system and other dimensions of each game in order to find design patterns that help support a ludemic approach. By addressing ludemes, the authors seek to contribute to understanding the success of modern board games in an age of video game domination.
IMPLEMENTASI EMPLOYEE RELATIONS DALAM MEMPERTAHANKAN CITRA POSITIF BNI FATMAWATI DI MASA PANDEMI COVID-19
Authors: Tarzani Tarzani , Sumarni Lilik
Published: October 2023

Bagian ini memuat ringkasan riset/ kajian yang terdiri dari latar belakang, tujuan penelitian, metode penelitian, hasil Dalam menghadapi situasi pandemi saat ini mengingat terjadi nya banyak penurunan dari segi performa perusahaan yang dialami hampir semua sektor industri serta berdampak kepada kondisi Citra Perusahaan. BNI Fatmawati menggunakan momentum ini sebagai landasan untuk menerapkan dan mengimplementasikan employee relations dalam keberlangsungan bisnisnya demi mencapai performa perusahaan yang lebih baik dan berkelanjutan serta dapat mempertahankan kondisi citra perusahaan yang telah dibangun selama ini. Tujuan dari penelitian ini adalah untuk mengetahui (1) Implementasi employee relations BNI Fatmawati dalam mempertahankan citra positif organisasi.(2) Bentuk-bentuk program implementasi employee relations BNI Fatmawati.(3) Kondisi citra organisasi.(4) Kekuatan, Kelemahan, Peluang dan Hambatan. Teori yang digunakan dalam penelitian ini adalah teori employee relations menurut Ruslan. dan teori citra menurut Kotler&Keller. Penelitian ini menggunakan pendekatan dan metode deskriptif kualitatif. Teknik pengumpulan data menggunakan wawancara dan dokumentasi dengan informan bagian Humas dan SDM. Untuk menguji keabsahan data, dilakukan uji triangulasi sumber. Hasil dari penelitian ini yaitu BNI Fatmawati melakukan implementasi employee relations melalui program-program seperti keterbukaan informasi manajemen, pendidikan dan pelatihan karyawan, penghargaan, special event, kemudian membentuk media komunikasi internal. Sehingga citra positif dapat dipertahankan dan implementasi employee relations ini mengalami beberapa peluang dan hambatan yang terjadi pada prosesnya.