bluuebunny/crossref_metadata_2025 huggingface dataset:
Hemimandibulectomy of an extensive complex odontoma in the mandible: a case report
Authors: Widayanti Retno , Priyanto Winarno , Rizki Kiki A. , Hardianto Andri
Published: April 2018

Objective: Odontomas are the most common form of odontogenic tumors of the jaw, represent a benign hamartoma rather than a true neoplasm. They constitute 22% of all odontogenic tumors. Odontomas are consist of two types, compound and complex. The compound odontomas contain recognizable enalmel, dentin and sometimes cementum, shaped in toothlike structures; whereas complex odontomas are composed of irregular masses of dentin and enamel and have no anatomic resemblance to a tooth.Methods: A17-year-old female patient came to Department of Oral and Maxillofacial Surgery with a slow growing and asymptomatic swelling in her left mandible. The panoramic radiograph showed a radioopacity and radiolucent lesion, with well-corticated limits. The radioopaque area was amorphous, circumscribed by a thin and irregular radiolucent halo. An inscisional biopsy confirmed the lesion as a complex odontoma. The surgery performed was hemimandibulectomy followed by a reconstruction using a plate under general anaesthesia.Results: Complex odontomas are most likely to be found in the posterior region of the maxilla or the mandible and can be treated with a simple enucleation and curettage. In this case report the hemimandibulectomy was performed due to the extensiveness of the mass.Conclusion: Surgical removal of large complex odontoma with hemimandibulectomy is a rare clinical scenario. The extensiveness of the lesion contributed to its removal technique.
Effect of topical application red betel (piper crocatum) leaf gel on clinical attachment level repair patient with chronic periodontitis
Authors: Herryawan Herryawan
Published: April 2018

Objective: The purpose of this study was to determine the effect of red betel (piper crocatum) leaf gel as adjunctive therapy of scaling and root planing to the clinical attachment level (CAL) repair in the treatment of chronic periodontitis.Material and Methods: This study is a randomized control trial, single-blind, split mouth method before and after treatment. 18 patients of chronic periodontitis, aged 30-62 years participated in the study. The study was conducted by dividing jaw of the subjects into 2 sides, test and control. Both sides were treated scaling and root planing, and the test side given additional topical application of red betel leaf gel. Evaluation of CAL was performed 1 month after treatment. The data were statistically analyzed using the paired t test for comparison before and after treatment on each side and the unpaired t test to compare the test and control side.Results: Improvement of CAL in the test side is better than the control side, while distobuccal test side showed the greatest improvement 31.4%.Conclusion: Topical application of red betel leaf gel in patients with chronic periodontitis can increase the clinical attachment level.
The effect of the thermoplastic nilon enterprises (valplast) on clove extract (syzygium aromaticum) in various concentrations on the color change
Authors: Wibawaningtyas Niken , Kristiana Dewi , Probosari Niken
Published: April 2018

Objective: To investigate the effect of soaking of thermoplastic nylon (valplast) on clove flower extract (syzygium aromaticum) as a denture cleanser with different concentration 0.8%, 1%, 1.2%, 1.4%, and 1.6% to the color change of thermoplastic nylon.Material and Methods: 30 samples were divided into 6 groups. The sample size is (10x10x1) mm. The first group was immersed in sterile aquades and the other groups were immersed in clove flower extracts of 0.8%, 1%, 1.2%, 1.4%, and 1.6% for 12 days. The light intensity then measured using densitometer.Results: One way anova test results obtained value 0.174 (p>0.05) which indicates that there is no significant difference in each group.Conclusions: This study are darker discoloration of the thermoplastic nylon at a concentration of 1.6% and lower color changes occurring at a concentration of 0.8%.
Psychosocial antecedents of prosocial behavior and its relationship with subjective well-being in adolescents
Authors: Sharma Shalini  . , Tomer Sachin  .
Published: April 2018

Prosocial behavior is a collective term covering all activities that are advantageous to other persons or the society in general (Piliavin, Dovidio, Gaertner, and Clark, 1981). It can be divided into three categories of altruism, helping, and cooperation. The notion of why certain people help more willingly than others, and with varied frequencies; and what purpose does it solve in a person's life by extending a helping hand to someone, is what led to the origin of this study. Literature review revealed there is sparse literature available on Indian adolescents. Thus, the research
objective is to explore various psychosocial factors that contribute to development of pro-social behaviour in late
adolescence, and how they contribute to the experience of an individual's subjective well-being. Sample consisted
of 200 college going students in the age group of 17-20 years. A variety of measures were used for the purpose:
Prosocial Tendencies measure, Satisfaction with life scale and Positive and Negative affect scale. In addition a semistructured
questionnaire was used to get qualitative data from 30 individuals. Data were analysed using descriptive
statistics, correlational techniques and t-test. Results indicated majority of students having an average frequency of
prosocial behavior, predominantly public and compliant type of prosocial behavior, a low positive correlation
between prosocial behavior and well-being, a significant difference between adolescents scoring low on pro-social
behavior from those scoring high in terms of their satisfaction with life and no significant difference between males
and females in terms of prosocial behavior tendencies.
How is happiness related to network of social relationships?
Authors: Moirangthem Sandhyarani Devi , Thingujam Nutankumar S.
Published: April 2018

The purpose of the present study was to examine the relationship between happiness and network of social relationships. Network of relationships inventory-relationship quality version (Furman and Buhrmester, 1985) and
subjective happiness scale (Lyubomirsky and Lepper, 1999) was administered on 100 undergraduate college students
at Gangtok, Sikkim within age range of 17 to 23 years. Pearson's correlation showed that happiness was
significantly positively related with companionship, approval and satisfaction with opposite-gender best-friends,
emotional support of mother, satisfaction with same-gender best-friends and siblings. However, happiness was
found to be negatively correlated with criticism and pressure of girl/boy friend, criticism of mother and siblings,
dominance of father, and exclusion of best friends (same/opposite gender), girl/boy friend, siblings, mother and
father.
New Failure Mode and Effects Analysis based on D Numbers Downscaling Method
Authors: Liu Baoyu , Hu Yong , Deng Yong
Published: April 2018

Failure mode and effects analysis (FMEA) is extensively applied to process potential faults in systems, designs, and products. Nevertheless, traditional FMEA, classical risk priority number (RPN), acquired by multiplying the ratings of occurrence, detection, and severity, risk assessment, is not effective to process the uncertainty in FMEA. Many methods have been proposed to solve the issue but deficiencies exist, such as huge computing quality and the mutual exclusivity of propositions. In fact, because of the subjectivity of experts, the boundary of two adjacent evaluation ratings is fuzzy so that the propositions are not mutually exclusive. To address the issues, in this paper, a new method to evaluate risk in FMEA based on D numbers and evidential downscaling method, named as D numbers downscaling method, is proposed. In the proposed method, D numbers based on the data are constructed to process uncertain information and aggregate the assessments of risk factors, for they permit propositions to be not exclusive mutually. Evidential downscaling method decreases the number of ratings from 10 to 3, and the frame of discernment from 2^{10} to 2^3 , which greatly reduce the computational complexity. Besides, a numerical example is illustrated to validate the high efficiency and feasibility of the proposed method.
Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-κB
Authors: Voelkl Jakob , Tuffaha Rashad , Luong Trang T.D. , Zickler Daniel , Masyout Jaber , Feger Martina , Verheyen Nicolas , Blaschke Florian , Kuro-o Makoto , Tomaschitz Andreas , Pilz Stefan , Pasch Andreas , Eckardt Kai-Uwe , Scherberich Juergen E. , Lang Florian , Pieske Burkert , Alesutan Ioana
Published: April 2018

Background The high cardiovascular morbidity and mortality of patients with CKD may result in large part from medial vascular calcification, a process promoted by hyperphosphatemia and involving osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs). Reduced serum zinc levels have frequently been observed in patients with CKD, but the functional relevance of this remains unclear.

Methods We performed experiments in primary human aortic VSMCs; klotho-hypomorphic (kl/kl), subtotal nephrectomy, and cholecalciferol-overload mouse calcification models; and serum samples from patients with CKD.

Results In cultured VSMCs, treatment with zinc sulfate (ZnSO4) blunted phosphate-induced calcification, osteo-/chondrogenic signaling, and NF-κB activation. ZnSO4 increased the abundance of zinc-finger protein TNF-α–induced protein 3 (TNFAIP3, also known as A20), a suppressor of the NF-κB pathway, by zinc-sensing receptor ZnR/GPR39-dependent upregulation of TNFAIP3 gene expression. Silencing of TNFAIP3 in VSMCs blunted the anticalcific effects of ZnSO4 under high phosphate conditions. kl/kl mice showed reduced plasma zinc levels, and ZnSO4 supplementation strongly blunted vascular calcification and aortic osteoinduction and upregulated aortic Tnfaip3 expression. ZnSO4 ameliorated vascular calcification in mice with chronic renal failure and mice with cholecalciferol overload. In patients with CKD, serum zinc concentrations inversely correlated with serum calcification propensity. Finally, ZnSO4 ameliorated the osteoinductive effects of uremic serum in VSMCs.

Conclusions Zinc supplementation ameliorates phosphate-induced osteo-/chondrogenic transdifferentiation of VSMCs and vascular calcification through an active cellular mechanism resulting from GPR39-dependent induction of TNFAIP3 and subsequent suppression of the NF-κB pathway. Zinc supplementation may be a simple treatment to reduce the burden of vascular calcification in CKD.
Four-Dimensional Imaging of T Cells in Kidney Transplant Rejection
Authors: Hughes Andrew D. , Lakkis Fadi G. , Oberbarnscheidt Martin H.
Published: April 2018

Kidney transplantation is the treatment of choice for ESRD but is complicated by the response of the recipient’s immune system to nonself histocompatibility antigens on the graft, resulting in rejection. Multiphoton intravital microscopy, referred to as four-dimensional imaging because it records dynamic events in three-dimensional tissue volumes, has emerged as a powerful tool to study immunologic processes in living animals. Here, we will review advances in understanding the complex mechanisms of T cell–mediated rejection made possible by four-dimensional imaging of mouse renal allografts. We will summarize recent data showing that activated (effector) T cell migration to the graft is driven by cognate antigen presented by dendritic cells that surround and penetrate peritubular capillaries, and that T cell–dendritic cell interactions persist in the graft over time, maintaining the immune response in the tissue.
Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure
Authors: Reichold Markus , Klootwijk Enriko D. , Reinders Joerg , Otto Edgar A. , Milani Mario , Broeker Carsten , Laing Chris , Wiesner Julia , Devi Sulochana , Zhou Weibin , Schmitt Roland , Tegtmeier Ines , Sterner Christina , Doellerer Hannes , Renner Kathrin , Oefner Peter J. , Dettmer Katja , Simbuerger Johann M. , Witzgall Ralph , Stanescu Horia C. , Dumitriu Simona , Iancu Daniela , Patel Vaksha , Mozere Monika , Tekman Mehmet , Jaureguiberry Graciana , Issler Naomi , Kesselheim Anne , Walsh Stephen B. , Gale Daniel P. , Howie Alexander J. , Martins Joana R. , Hall Andrew M. , Kasgharian Michael , O’Brien Kevin , Ferreira Carlos R. , Atwal Paldeep S. , Jain Mahim , Hammers Alexander , Charles-Edwards Geoffrey , Choe Chi-Un , Isbrandt Dirk , Cebrian-Serrano Alberto , Davies Ben , Sandford Richard N. , Pugh Christopher , Konecki David S. , Povey Sue , Bockenhauer Detlef , Lichter-Konecki Uta , Gahl William A. , Unwin Robert J. , Warth Richard , Kleta Robert
Published: April 2018

Background For many patients with kidney failure, the cause and underlying defect remain unknown. Here, we describe a novel mechanism of a genetic order characterized by renal Fanconi syndrome and kidney failure.

Methods We clinically and genetically characterized members of five families with autosomal dominant renal Fanconi syndrome and kidney failure. We performed genome-wide linkage analysis, sequencing, and expression studies in kidney biopsy specimens and renal cells along with knockout mouse studies and evaluations of mitochondrial morphology and function. Structural studies examined the effects of recognized mutations.

Results The renal disease in these patients resulted from monoallelic mutations in the gene encoding glycine amidinotransferase (GATM), a renal proximal tubular enzyme in the creatine biosynthetic pathway that is otherwise associated with a recessive disorder of creatine deficiency. In silico analysis showed that the particular GATM mutations, identified in 28 members of the five families, create an additional interaction interface within the GATM protein and likely cause the linear aggregation of GATM observed in patient biopsy specimens and cultured proximal tubule cells. GATM aggregates-containing mitochondria were elongated and associated with increased ROS production, activation of the NLRP3 inflammasome, enhanced expression of the profibrotic cytokine IL-18, and increased cell death.

Conclusions In this novel genetic disorder, fully penetrant heterozygous missense mutations in GATM trigger intramitochondrial fibrillary deposition of GATM and lead to elongated and abnormal mitochondria. We speculate that this renal proximal tubular mitochondrial pathology initiates a response from the inflammasome, with subsequent development of kidney fibrosis.
NPHP1 (Nephrocystin-1) Gene Deletions Cause Adult-Onset ESRD
Authors: Snoek Rozemarijn , van Setten Jessica , Keating Brendan J. , Israni Ajay K. , Jacobson Pamala A. , Oetting William S. , Matas Arthur J. , Mannon Roslyn B. , Zhang Zhongyang , Zhang Weijia , Hao Ke , Murphy Barbara , Reindl-Schwaighofer Roman , Heinzl Andreas , Oberbauer Rainer , Viklicky Ondrej , Conlon Peter J. , Stapleton Caragh P. , Bakker Stephan J.L. , Snieder Harold , Peters Edith D.J. , van der Zwaag Bert , Knoers Nine V.A.M. , de Borst Martin H. , van Eerde Albertien M.
Published: April 2018

Background Nephronophthisis (NPH) is the most prevalent genetic cause for ESRD in children. However, little is known about the prevalence of NPH in adult-onset ESRD. Homozygous full gene deletions of the NPHP1 gene encoding nephrocystin-1 are a prominent cause of NPH. We determined the prevalence of NPH in adults by assessing homozygous NPHP1 full gene deletions in adult-onset ESRD.

Methods Adult renal transplant recipients from five cohorts of the International Genetics and Translational Research in Transplantation Network (iGeneTRAiN) underwent single-nucleotide polymorphism genotyping. After quality control, we determined autosomal copy number variants (such as deletions) on the basis of median log2 ratios and B-allele frequency patterns. The findings were independently validated in one cohort. Patients were included in the analysis if they had adult-onset ESRD, defined as start of RRT at ≥18 years old.

Results We included 5606 patients with adult-onset ESRD; 26 (0.5%) showed homozygous NPHP1 deletions. No donor controls showed homozygosity for this deletion. Median age at ESRD onset was 30 (range, 18–61) years old for patients with NPH, with 54% of patients age ≥30 years old. Notably, only three (12%) patients were phenotypically classified as having NPH, whereas most patients were defined as having CKD with unknown etiology (n=11; 42%).

Conclusions Considering that other mutation types in NPHP1 or mutations in other NPH-causing genes were not analyzed, NPH is a relatively frequent monogenic cause of adult-onset ESRD. Because 88% of patients had not been clinically diagnosed with NPH, wider application of genetic testing in adult-onset ESRD may be warranted.
Isıl Konfor Sıcaklıklarına Bağlı Olarak Bir Konutun Enerji Performansının Değerlendirmesi: İzmir Örneği
Authors: YILDIRIM ÖZCAN Nurdan , KUZGUNKAYA Ebru , GÖKÇEN AKKURT Gülden
Published: April 2018

Türkiye’de
enerji tüketiminin yaklaşık %34’ü binalarda ve bunun %85 kadarı da ısıtma ve
soğutma amaçlı kullanılmaktadır. Binalarda bulunan HVAC sistemlerinin işletme
özellikleri, hem binanın ısıl konforunu hem de enerji tüketimlerini doğrudan
etkilemektedir. Bu çalışmada, HVAC sistemlerinin işletme şartlarının, ısıl
konfor koşulları ile enerji tüketimlerine olan etkisinin belirlenmesi
amaçlanmaktadır. Bu amaçla İzmir ilindeki 100 m2’lik bir konut için
öngörülen HVAC sisteminin kesikli ve sürekli rejimde, tek ve çift sıcaklık set
değerleri ile tam mekanik kontrollü veya doğal havalandırmalı olarak
çalıştırılması durumları incelenmiştir.

 

Isıl
konfordan olan memnuniyet PMV değeri ile ifade edilmektedir. Bu kapsamda
öncelikle, Design Builder yazılımı kullanılarak en iyi duruma karşılık gelen
PMV=0’a göre HVAC sisteminin set sıcaklıları belirlenmiştir. Bu sıcaklık set
değerlerinin kullanılması ile ele alınan 5 farklı durumda konut için yıllık
birim ısıtma/soğutma enerji tüketimleri, birim birincil enerji tüketimi, yıl
boyunca ailenin evde bulunduğu saatlerde sağlanan PMV değerleri ve PMV
değerlerinin istatistiksel değerlendirilmesi gerçekleştirilmiştir. Elde edilen
sonuçlara göre, incelenen 5 durum arasında normal beklenti seviyesinde % 99,6
kümülatif frekans yüzdesi ile ısıl konforu en çok sağlayan tam mekanik
kontrollü, sürekli rejim, aylık çift ısıtma/soğutma operatif sıcaklık set
değerli durumdur. Tam mekanik kontrollü, kesikli rejim, aylık tek
ısıtma/soğutma hava sıcaklığı set değerli durum ise 2,04 kWh/m2/%KF
birim memnuniyet enerji tüketimi değeri ile en az enerji tüketen durum
olmaktadır.
Genel İndirgenmiş Gradyan Metodu ile Eniyileme Çözücüsü Geliştirilmesi
Authors: Toplu Mehmet Samet , Körpe Durmuş Sinan
Published: April 2018

Bu
çalışmada, literatürde bulunan bir denek taşı eniyileme probleminin çözümü için
genel indirgenmiş gradyan metodu kullanılarak eniyileme çözücüsü geliştirilir.
Eniyileme çözücüsü geliştirilmesinde MATLAB programlama dili kullanılır. Denek
taşı probleminde hedef fonksiyon, tasarım değişkenleri olarak tanımlanan farklı
genişlik ve yükseklik değerlerine sahip N adet parçadan oluşan bir destekli
kirişin hacmini en aza indirgenmesidir. Kirişin her bir parçasının sol ucundaki
eğilme gerilmesi, fonksiyonel kısıtlama olarak tanımlanırken her parçadaki
genişliğin yüksekliğe oranı ise geometrik kısıtlama olarak tanımlanır.
Geliştirilen çözücü ve MATLAB içinde olan ardışık ikinci derece programlama
metodu ile elde edilen sonuçlar karşılaştırılır ve 25 parça için uygun
parametreler elde edilir. Sonuç olarak, genel indirgenmiş gradyan metodu ile
geliştirilen çözücünün eniyileme problemlerinin çözümünde kullanılabilecek
uygun bir çözücü olduğu testlerle gösterilmiştir.
The treatment of Slaughterhouses wastewater by An Up Flow - Anaerobic Sludge Blanket (UASB) reactor.
Authors: SAGHİR Abdullah , HAJJAR Salwa
Published: April 2018

Slaughterhouse wastewater is heavily polluted. It
contains a high concentration of oil and grease, phosphorus, nitrogen, organic
matter and suspended solids.

The
objective of the research is study the ability of slaughterhouses wastewater
treatment by a UASB reactor and define the best hydraulic retention time (HRT).

This research focuses on the treatment of slaughterhouse
wastewater in Up Flow Anaerobic Sludge Blanket (UASB) reactor In these
reactors, the polluted wastewater rises slowly which allows it to form a suspended
sludge blanket. Granules of sludge gather on the surface and anaerobic bacteria
is activated which feeds on the organic matter which exists in the liquid.

The research includes a study of the effect of hydraulic
retention time (HRT) on the efficiency of treatment in UASB reactors at a constant
temperature of about 30±1°C.
The experiments have illustrated that it is possible to achieve excellent
removal efficiency for high concentrations of COD when the temperature of the wastewater
is fixed at 30±1 °C. The
removal efficiency fit with hydraulic retention times (HRTs) in UASB reactor, for
the following values of HRTs:(6,12,18,24,30,36) hours, the removal efficiencies of COD were:(35.78%,48.93%,56.15%,71.3% ,76.33%,83.37%) respectively.
Kabiliyet odaklı sanayi kümelenmesi: Sakarya Üniversitesi teknokent örneği
Authors: DENİZHAN Berrin , YILMAZ YALÇINER Ayten
Published: April 2018

Sanayi kümelenmesi, bölgesel
kalkınmanın en başarılı araçlarından biri olarak kabul edilmektedir. Bu
çalışmanın amacı ise kabiliyet odaklı kümelenme yaklaşımını Sakarya
Üniversitesi Teknokent’te yer alan firmaların kabiliyetlerinin ortaya
çıkarılması ile ortaya koymaktır. İlk olarak Teknokent’te faaliyet gösteren
firmalara anket uygulaması ile firma kabiliyetleri ortaya çıkarılmıştır.
Anketler SPSS 18 programı ile değerlendirilmiştir. Anket sonucu elde edilen
kabiliyet alanlarına göre derece sıralama ve kümeleme (ROC) algoritması ile
firmaların kümelenmesine yönelik önerilerde bulunulmuştur. ROC algoritması
sanayi kümelenmesi üzerinde uygulanabileceği gibi kabiliyet odaklı kümelenme
yaklaşımı Teknokentin verimliliğini de artırabilecektir. Sakarya bölgesinin
kalkınmasına etki edebilecek potansiyel gücün ortaya çıkarılmasına da katkı
sağlayacaktır
Anti-kanser ilacı imatinib’in elektro-oksidasyon prosesi ile gideriminin yüzey yanıt metodu kullanılarak incelenmesi
Authors: TÜRKAY Özge , BARIŞÇI Sibel , DİMOGLO Anatoli
Published: April 2018

Atıksularında bulunan farmasötikler
sucul canlılar üzerinde oldukça toksik olmaları nedeniyle büyüyen bir endişe
haline gelmektedir. Atıksularda ve yüzeysel sularda farmasötiklerin
konsantrasyonları µg/L ve ng/L gibi çok düşük seviyelerde olmasına rağmen
bunların kronik etkileri nedeniyle ciddi ve acil bir araştırmaya gerek
duyulmaktadır. Bu çevre ve sağlık problemlerinine yol açan farmasötik mikrokirleticileri
atıksulardan gidermek için klasik arıtma yöntemleri yetersiz olması sebebiyle
ileri arıtma yöntemlerine ihtiyac duyulmaktadır. Özellikle elektrokimyasal
prosesler bu tür mikrokirleticileri arıtmak için oldukça başarılı yöntemler
olarak dikkat çekmektedir. Bu çalışmada, Imatinib (IMT) adlı etken maddenin
elektro-oksidasyon yöntemi ile arıtılması çalışılmıştır. Imatinib etken
maddesinin arıtılması için kimyasal-elektrokimyasal stabiliteye sahip Ti/RuO2
elektrotu kullanılmıştır. Optimum çalışma şartlarının belirlenmesi amacıyla
yüzey yanıt metodu (YYM) kullanılarak proses optimizasyonu yapılmıştır.
Deniz dibi tarama malzemesinin faydalı kullanımı için yıkama-eleme tesisi tasarımı ve yıkama-eleme prosesi atıksuyunun yönetimi
Authors: BAŞAR H. Merve , GÜZEL Barış , ÖZER-ERDOĞAN Pembe , MURAT-HOCAOĞLU Selda , ÖZEL Doğan , ERGENEKON Şeyla , TOLUN G. Leyla
Published: April 2018

Bu çalışma, dip tarama
faaliyetleri neticesinde ortaya çıkan dip tarama malzemelerinin (DTM) beton
uygulamalarında ince agrega olarak faydalı kullanımı için bir yıkama-eleme
tesisi tasarlanmasını, bu tesise ait ilk yatırım ve işletme maliyetlerinin
ortaya konulmasını ve laboratuvar ölçekli DTM yıkama-eleme denemeleri sonucunda
ortaya çıkan atıksuyun karakterizasyonunun ve yönetiminin belirlenmesini kapsamaktadır.
Bu çalışma ile DTM’nin yıkama-eleme ön işlemine tabi tutulması durumunda yüksek
klorür, sülfat ve su içeriğinin giderilerek ince agrega olarak beton
çalışmalarında kullanılabileceği, oluşan yıkama-eleme atıksuyunun
kanalizasyona/denize deşarjına risk oluşturacak herhangi bir kirletici
içermediği tespit edilmiş olup olası 1.500 m3/gün kapasiteli DTM
yıkama-eleme tesisinin ilk yatırım ve işletme maliyetlerinin sırasıyla
6.753.600 TL ve 2.366.810 TL ve birim maliyeti ise 6,3 TL/ton olarak
hesaplanmıştır.
Sol-jel yöntemi ile zirkonyum fosfat ve poli (etilen oksit) temelli polimer kompozit malzeme (ZRP/PEO) sentezi ve karakterizasyonu
Authors: Çelik Küçük Asuman , Demirkal Emrah
Published: April 2018

Bu çalışmada,  sol-jel
yöntemi ile tetraetil ortosilikat (TEOS) ön başlatıcısı varlığında zirkonyum
fosfat  (ZrP) ve Poli (etilen oksit)
temelli ZrP/ PEO kompozit malzemesi üretilmiştir. Hazırlanan malzemenin yapısı
X-ışını difraksiyonu (XRD) ve Fourier transform IR spektroskopisi (FTIR)
yöntemleri ile incelenmiştir. Isısal özellikleri ise termal gravimetrik analiz
(TGA) ile incelenmiştir. TGA analizinde, sentezlenen malzemenin 300 °C’e kadar
kararlı olduğu bulunmuştur. Üretilen bu malzemenin maliyeti düşüktür, ayrıca
ısıtıldığında 100 °C’nin üzerindeki sıcaklıklarda 300 °C ye kadar bozulmaya
uğramamaktadır. 300 °C’ye kadar olan ısısal kararlılığı ve su tutma kabiliyeti
sayesinde ZrP/PEO kompozit malzemesi, ara sıcaklık yakıt pillerinde
kullanılabilme potansiyeline sahiptir.
Multilevel Reversible Video Watermarking with Improvement on Occluded Areas
Authors: Yıldırım İbrahim
Published: April 2018

This paper investigates the influence of the occlusion in
reversible video watermarking technique based on histogram modification of
motion compensated prediction error and presents a novel reversible video
watermarking algorithm which has better embedding capacity and PSNR in occluded
areas. In occluded areas, conventional motion estimation techniques calculate
higher prediction error. Therefore, watermarking algorithm which exploits
prediction error has small embedding capacity and poor image quality. To reduce
the prediction error, occlusion detection algorithms must be employed in motion
estimation.
Bor oksit tozunun fren balatalarının tribolojik özelliklerine etkisi
Authors: Akıncıoğlu Gülşah , Uygur İlyas , Öktem Hasan , Akıncıoğlu Sıtkı
Published: April 2018

Bu çalışmada, Renault Clio
otomobilin fren balatası, bor oksit tozu katkısı ile sıcak presleme yöntemiyle
üretilerek, bor oksit tozunun balatanın tribolojik özellikleri üzerine etkisi
deneysel olarak araştırılmıştır. Son yıllarda çevre dostu malzemelerin
kullanılmasının önem kazanmasından dolayı fren balatasının içeriğinde bor oksit
kullanılmıştır. Ayrıca bu malzemenin seçilmesinde ülke ekonomisine fayda
sağlamakta amaçlanmıştır. Karşılaştırma yapmak için ticari Clio balatası
kullanılmıştır. Balata numunelerinin aşınma sürtünme deneyleri Chase tipi
cihazda yapılmıştır. Bor oksit katkısının fren balatasının aşınma sürtünme
performansına etkisi ticari fren balatasının sonuçlarıyla kıyaslanarak
incelenmiştir. Sonuçta bor oksit katkısının sürtünme katsayısına olumlu etki
yaptığı gözlenmiştir.
Karma Taguchi ve yüzey yanıt yöntemi kullanılarak astm b574 (hastelloy c-22)'in tornalanması esnasındaki işleme parametrelerinin yüzey pürüzlülüğüne etkisinin incelenmesi ve kesme parametrelerinin optimizasyonu
Authors: Basmacı Gültekin , KIRBAŞ İsmail , AY Mustafa , PEKER Musa
Published: April 2018

Bu çalışmada ASTM B574
(Hastelloy C-22) malzemesi üzerinde tornalama işlemi sonrasında kesme
parametrelerinin (kesme derinliği, kesme hızı, radius, ilerleme hızı, debi,
talaş açısı, yanaşma açısı) yüzey pürüzlüğü ve sıcaklık üzerindeki etkileri
incelenmiştir. Kesme parametrelerini etkileyen faktörleri belirlemek için varyans
analizi (ANOVA) uygulanırken, yüzey pürüzlülüğünü etkileyen parametrelerin
optimizasyonu Taguchi ortogonal deney tasarımına dayanan Tepki Yüzeyi
Metodolojisi (RSM) ile elde edilmiştir. Geliştirilen modellerin yüzey pürüzlülüğü
ve sıcaklık tahmini için gerekli olan doğruluğu oldukça başarılıdır. Ölçüt
olarak  değerinin kullanıldığı çalışmada ortalama Ra yüzey
pürüzlüğü için %93.85, doğruluk değeri elde edilmiştir. ANOVA analizleri
sonucunda %95 güven aralığında, Ra için en etkili parametreler sırasıyla kesme
hızı, yanaşma açısı, talaş açısı ve debi olarak tespit edilmiş ve en düşük
yüzey pürüzlüğü oranı için en uygun kesme parametre değerleri belirlenmiştir.
Frenli tas menteşe kinematik, kinetik ve yorulma analizi
Authors: Bayraktar Meral , Bilyaz Hidayet , Demir Cihan
Published: April 2018

Bu çalışmada, mobilya sektöründe sıklıkla kullanılan menteşe
çeşitlerinden düz frenli tas menteşelerin kinematik, statik ve yorulma
analizleri yapılmıştır. Bu kapsamda menteşenin katı modellenmesi paket program
kullanılarak yapılmıştır. Menteşe kinetik ve kinematik analizi, çok parçalı
gövde analizi programı ile yapılmıştır. Bu analizden elde edilen yatak ve
mafsal kuvvetleri kullanılarak, yapının sanki-statik analizi için sonlu
elemanlar programı kullanılmıştır. Analizler TS EN 15570 standardı göz önüne
alınarak yapılmıştır. Yorulma analizi değerlendirmeleri ile yapıda
değişiklikler önerilmiştir. Sistem için, çok parçalı gövde analiz programı ile
yapılan kinematik ve kinetik analiz sonuçlarının, sonlu elemanlar yöntemi ile
statik ve yorulma analizinde kullanılması, sonlu elemanlar programı geçici
cevap analizine alternatif olarak gösterilmiştir.
The theoretical investigation of global reactivity descriptors, NLO behaviours and bioactivity scores of some norbornadiene derivatives
Authors: Eryılmaz Serpil
Published: April 2018

In this study, global reactivity descriptors such as ionization potential, electron affinity, electronegativity, chemical hardness, softness and electrophilicity index of norbornadiene derivatives which include some halogen atoms and atom groups, have been investigated with DFT/BPV86/B3LYP/B3PW91 methods with 6-31G(d,p) basis set. To determine the non-linear optical behaviours of the structures, the total dipole moment,  polarizability,and first-order hyperpolarizabilityvalues have been examined at the same theoretical level. It has been determined that thiol-bonded groups on comparison with others have a much better NLO material property. In addition, the potentials of the structures as drug-active compounds have been inspected with Lipinski’s rule of 5 and bioactivity scores. Thiol and hydroxyl-bonded groups have a good drug-likeness and bioactivity score relative to the others.
Evaluation of Two Stage Modified Ridge Estimator and Its Performance
Authors: Toker Selma , ÖZBAY Nimet
Published: April 2018

Biased
estimation methods are more desirable than two stage least squares estimation
for simultaneous equations models suffering from the problem of
multicollinearity. This problem is also handled by using some prior information.
Taking account of this knowledge, we recommend two stage modified ridge
estimator. The new estimator can also be evaluated as an alternative to the
previously proposed two stage ridge estimator. The widespread performance
criterion, mean square error, is  taken
into consideration to compare the two stage modified ridge, two stage ridge and
two stage least squares estimators. A real life data analysis is investigated
to prove the theoretical results in practice. In addition, the
intervals of the biasing parameter which provide the superiority of the two
stage modified ridge estimator are determined 
 with the help of figures. The
researchers who deal with simultaneous systems with multicollinearity can opt for
the two stage modified ridge estimator.
Improving Physical Properties of Plant Growing Medias Using Perlite
Authors: ÖZER Hasan , Dede Ömer Hulusi
Published: April 2018

The most widely used growing
media in the production of potted ornamental plants is peat. However, the
studies for alternative solutions are being conducted due to the reasons such
as restricted peat sources, high cost, destruction of natural environment due
to peat production and variability in the quality of produced peat. In the
relevant literature, there are two basic ideas on which the studies have
focused on. The first one is the development of new growing media using organic-origin
wastes, the second one is the preparation of the mixtures in which organic and
inorganic materials are used as a component of growingmediums. In this study
which was prepared in parallel with the relevant main ideas in the literature,
the effects of perlite utilization on the physical properties of indigenous
peat, and on those of the growing media obtained from hazelnut cinder, which is
among agricultural organic materials in our country and has considerable  potential to be the most important
alternative of peat, were investigated. For this purpose, the physical
properties of the growingmedias, prepared by mixing perlite with raw peat and
hazelnut husk, at various ratios (10,15,20,25%), were investigated, and the
results obtained were compared with sphagnum peat, and with desired properties
for ideal growingmedias, in the literature. When the results obtained from the
study were examined, it was seen that as well as the highest values were
observed in the mixtures using 25% perlite, the perlite addition increased the porosity
of raw peat by 68.25% and air capacity by 30.03%, and that the hazelnut husk
decreased air capacity, higher than the ideal values,  by 47.19%,thus approximating it  its ideal value range. With increasing perlite
ratio in the mixtures, the organic substance contents and water holding
capacities of the growingmedias decreased as their pH values increased.
However, in applications using 25% Perlite, the shrinkage rates of raw peat and
hazelnut husk were found as 17.05% and 6.41% respectively,  and the water resuction times of those were
found as 1.52 and 1.21 minutes, respectively. Based on these results, it can be
said that the most important contribution of perlite utilization for raw peat
and hazelnut husk is to decrease shrinkage rates and water resuction times, and
that this improvement will avail in preventing the damages that occur in plant
roots due to  drying and shrinking of the
growing media, and in decreasing  the
irrigation frequency.
Promotion of Cultural Heritages Through A Virtual Museum Platform: Case Study Hagia Sophia
Authors: DÖKER Mehmet Fatih , KIRLANGIÇOĞLU Cem
Published: April 2018

The Digital
World has become the most significant platform for spreading the written and
visual documents about cultural and historical heritages in accordance with the
recent developments on web based technologies. All kind of digital platforms
such as notebooks, personal computers, tablets and mobile phones are the
primary tools to transfer local values to global scale. Nevertheless, it is not
possible to say that these technological opportunities are not used efficiently
to promote museums keeping the inheritance and memory of societies.
Fortunately, 3D game technologies and virtual reality applications have been
started to use in this area. The traditional promotion methods are being
replaced by these new and innovative solutions including ‘virtual museum’ term.
People are capable to use this platform to see and interactively walk through
the virtually reconstructed museums in a 3D digital environment. Creating
accessible web based virtual museum platforms will attract tourists, students
and researchers from all ages. The aim of this study is to create a virtual
museum platform including all kind of written and visual materials. Hagia
Sophia has been selected as the case study area of this study and digitally
reconstructed to use in the project.
The First Indoor Radon Gas Measurement at Historical Places in Cappadocia, Nigde, Turkey
Authors: Bozkurt Vakkas , Ertürk Sefa
Published: April 2018

The aim of this study is to
determine the concentration of Radon and its annual effective dose at the Nigde
Museum and in a number of historical places namely the Sungur Bey, the
Alaeddin, the Disari mosque and the Ak Medrese Culture House in Cappadocia,
Nigde, Turkey by using a nuclear track detector CR-39 to ascertain how much
Radon concentration affects the people who are working in or visiting such
places. Nuclear track detectors CR-39 were used for measurement for 132 days at
the Nigde Museum, and for 63 days in the historical places. The exposed nuclear
track detectors were then sent to the Sarayköy Nuclear Research and Training
Center (SANAEM) to determine of Radon-222. The average Radon concentration
results obtained for the Nigde Museum, the Sungur Bey, the Alaeddin, the Disari
mosques and the Ak Medrese Culture House were 13.0±2.94 Bq/m3,
31.67±3.86 Bq/m3, 52.0±5.72 Bq/m3, 42.67±19.34 Bq/m3
and 31.0±4.55 Bq/m3 respectively. The average effective dose of
Radon was calculated for the Nigde Museum, the Sungur Bey, the Alaeddin, the
Disari mosques and the Ak Medrese Culture House in Nigde and was found to be
approximately 0.137 mSv/y, 0.062 mSv/y, 0.103 mSv/y, 0.084 mSv/y and 0.327
mSv/y respectively
A Lyapunov Function For Logistic Equation On Time Scales
Authors: Hatipoğlu Veysel Fuat
Published: April 2018

In this study we focus on the stability of dynamic logistic equation which is used in single species population dynamics. Here we have introduced a quadratic Lyapunov function for generalized dynamic logistic equation on time scales. By using proposed Lyapunov function, asymptotic stability conditions for the equilibrium solution of dynamic logistic equation have been investigated.
Optimal Energy Production In The Yeşilirmak River Basin
Authors: Opan Mücahit , Bacaksız Efsun
Published: April 2018

Optimal planning and operation of water resources are
depend on a complex structure and process that include country economics and
life standards. Currently, sustainable use and development of water resources
to maximize possible benefits are the two big challenges to be overcome and
efficient use of hydro power forms a significant component of this. In this
study, a water resources system with multi-objectives and multiple reservoirs
is described. It is considered to three scenarios in this system. The system is
set up on the optimal operation model for the long term planning. The technique
of the dynamic programming with successive approximations is used for
the model. Objective
function in the optimization model has two stage, maximization of firm and
total energies. The model is applied to a water resources system with
multi-objective and multiple reservoirs presented successively on the main and
secondary line of the Yeşilırmak River in the Yeşilırmak River Basin.  Results obtained are evaluated to
the maximization of the energy production. Accordingly, the firm energy
obtained from the optimal operational model for long term planning is presented
approximate the value determined by empiric equations, and also the average
energy in the model is % 32 better than the value determined by empiric
equations. It is observed that the optimization process of the reservoirs with
the highest operational storage was controlled and managed.
A structure calculation for hydrogen like nobelium
Authors: Ürer Güldem
Published: April 2018

The hydrogen
like ion is the simplest structure of an atom, so the studying on it gives a
change to test of methods using for determinating of atomic structures. It is
also an occasion the studying on hydrogen like ions to understand atomic
structure. For this reason, it is performed a study for hydrogen like nobelium
(No101+, Z=102). The calculating level structure of No101+
have been used both multiconfiguration Hartree-Fock and multiconfiguration
Dirac-Fock method. The calculations have contained some relativistic
corrections and quantum electrodynamic effects. There are very few theoretical
works in available literature and no experimental one for No101+. The
calculated results have been interpreted in comparison with other theoretical
results.
Flood Frequency Analysis of Akçay Stream
Authors: Sandalcı Mehmet
Published: April 2018

It is extremely important to predict flood forecasts
in planning water systems and reducing flood damage. For the Akçay stream,
which is one of the important branches of the Sakarya river , the flood
forecasts that can be seen at certain time frequencies have been estimated.
Normal (Gauss), log-normal and Gumbel distributions have been estimated in this
context. The Kolmogorov-Smirnov test investigated the suitability of the
distributions and found that the log-normal distribution was appropriate. As a
result, the 100-year flood plain was found to be 7,52 m3/sec  on log-normal distribution.
Yenilenebilir Enerji, Çevre ve Ekonomik Büyüme İlişkisi: Seçilmiş Ülkeler için Ampirik Bir Analiz
Authors: Acaravcı Ali , Erdoğan Sinan
Published: April 2018

Bu
çalışma, yenilenebilir enerji üretiminde dünya sıralamasında ilk beş içinde yer
alan ülkeler için çevre kirliliği, yenilenebilir enerji üretimi ve gelir
arasındaki uzun dönemli ilişkileri, dinamik panel veri yöntemleri kullanılarak
1992-2013 dönemi için incelemeyi amaçlamaktadır. Yatay kesit bağımlılık testi
sonuçları, tüm değişkenler ve model için yatay kesit bağımlılığın olduğunu
göstermektedir. Analiz sonuçları şu şekilde özetlenebilir: i) Durağan olmayan
değişkenler arasında uzun dönemli bir ilişki mevcuttur. ii) Yenilenebilir
enerji üretimi, çevre kirliliği üzerinde negatif bir etkiye sahiptir. iii) Kişi
başı gelir, çevre kirliliği üzerinde pozitif etkiye sahiptir. İncelenen
ülkelerde, yenilenebilir enerji üretiminin artışı, çevre kirliliğinin azaltılmasına
ve iktisadi büyüme-çevre çatışmasının çözümüne katkıda bulunacaktır.
untitled protocol v1
Authors: Janeth Fonseca mendoza Dora
Published: April 2018

Background: Warfarin is an oral anticoagulant associated with adverse reaction drugs due to wide inter- and intra-individual dosage variability. Warfarin dosage has been related to non-genetic and genetic factors. CYP2C9 and VKORC1 gene polymorphisms influence warfarin metabolism and dosage. Due to the central role of populations’ ethnical and genetic origin on warfarin dosage variability, novel algorithms for Latin American subgroups are necessary to establish safe anticoagulation therapy. Patients and Methods: We assessed CYP2C9*2 (c.430C>T), CYP2C9*3 (c.1075A>C), CYP4F2 (c.1297G>A) and VKORC1 (-1639G>A) polymorphisms in 152 patients who received warfarin. We evaluated the impact on the variability of patients’ warfarin dose requirements. Multiple linear regression analysis, using genetic and non-genetic variables, was used for creating an algorithm for optimal warfarin maintenance dose. Results: Median weekly prescribed warfarin dosage was significantly lower in patients having the VKORC1 -1639 AA genotype and poor CYP2C9*2/*2,*2/*3 metabolizers than their WT counterparts. We found a 2.3-fold increase in mean dose for normal sensitivity patients (wild type VKORC1/CYP2C9 genotypes) compared to the other groups (moderate and high sensitivity); 31.5% of the patients in our study group had warfarin sensitivity-related genotypes. The estimated regression equation accounted for 44.4% of overall variability regarding warfarin maintenance dose. The algorithm was validated, giving 45.9% correlation (R2=0.459). Conclusions: Our results describe and validate the first algorithm for predicting warfarin dose in a Colombian mestizo population and have contributed towards understanding pharmacogenetics in a Latin America population subgroup.
Pengaruh Pengaturan Block snd Random Practice Terhadap Hasil Belajar Forehand dan Backhand Groundstroke dalam Permainan Tenis
Authors: Ratnasari Desy , Suntoda Andi
Published: April 2018

Tujuan dari penelitian ini adalah untuk mengetahui pengaturan block dan random practice terhadap hasil belajar forehand dan backhand groundstroke dalam permainan tenis. Metode yang digunakan adalah metode eksperimen dengan desain Pretest-Posttest Group Design. Sampel yang digunakan adalah sampel purposive yang dipilih melalui kriteria sebanyak 30 orang dengan klasifikasi (age ± 19), (tb ± 155), (bb ± 45), (22 laki-laki, 8 perempuan) kemudian dibagi kelompok block practice dan kelompok random practice. Hasil peningkatan terhadap belajar forehand, rata-rata skor block practice meningkat sebesar 8.60 (Sig. < 0.05) dan rata-rata skor random practice meningkat sebesar 5.80 (Sig. < 0.05). Sedangkan pada hasil belajar backhand, kedua metode tersebut tidak memberikan peningkatan yang signifikan yaitu rata-rata skor block practice adalah 2.53 (Sig. > 0.05) dan rata-rata skor random practice -1.46 (Sig. > 0.05). Perbandingan peningkatan hasil belajar forehand dan backhand antara metode block practice dan random practice tidak mengalami peningkatan yang signifikan (Sig. > 0.05). Sehingga dapat disimpulkan bahwa metode block dan random practice meningkatkan secara signifikan hasil belajar pada pukulan forehand namun tidak pada pukulan backhand. Di sisi lain perbandingan peningkatan hasil belajar antara kedua metode tersebut tidak menunjukan hasil yang signifikan baik itu pada pukulan forehand maupun backhand dalam permainan tenis.
THE PREDICTIVE ROLE OF CONSTRUCTIVE THINKING ON ATTRIBUTIONS AND MARITAL SATISFACTION
Authors: Demirtaş Ayşe Sibel , Baytemir Kemal , Güllü Ali
Published: April 2018

In this study, the relationships between constructive
thinking, attributions and marital satisfaction in married individuals were
investigated and tried to reveal the predictive role of constructive thinking
on attributions and marital satisfaction. Correlational research design was
used in the study. The study group of the research consisted of a total of 202
married individuals, 142 females and 60 males. In order to collect data Constructive
Thinking Inventory, Relational Attribution Measure and Marital Life Scale were
used. Pearson product-moment correlation analysis and multiple regression analysis were used in the analysis of the data. According the results of
multiple regression analysis in order to reveal what extent to constructive
thinking predicts attributions it is seen that the model as a whole is
meaningful and the variables in the model all explain 20% of the total variance
of attributions. According to the results, emotional coping and superstitious
thinking have highest contribution on the model. According to the results of the multiple regression analysis
in order to reveal what extent to constructive thinking and attributions
together predict marital satisfaction, it is seen that the model as a whole is
meaningful. The variables in the model all explain 47% of the total variance of
marital satisfaction. Causal attributions, total attributions and behavioral
coping have highest contribution on the second model.
Training features for the tourism industry
Authors: Kurilova Elina V , Chikurova Tatiana J
Published: April 2018

This article discusses the development of tourism in Russia at the present day stage, which is closely related to the training of highly qualified personnel. Topical tasks are training, improvement in qualification, cross training of specialists in tourism industry based on the dual approach.
Management of natural disasters (a synopsis of the concept paper”Integrated flood management”)Management of natural disasters (a synopsis of the concept paper”Integrated flood management”)
Authors: Bolshanik Petr V
Published: April 2018

This article introduces a new approach to integrated management system as a means of using a process of forecasting and flood management.
The relationship of globalization and regionalization on the example of the Khanty-Mansiysk Autonomous okrug-Yugra
Authors: Islamutdinova Dina F
Published: April 2018

The development of regionalization in the context of international relations. Globalism and regionalism are considered one-directional: the interdependence, the growth of cross-border movement of factors of production, focus on solving environmental and social problems.
The genesis of the concept of “reverse logistics”
Authors: Shakhnazaryan Sergey A
Published: April 2018

The article deals with the evolution of views on the concept of “reverse logistics” among foreign and domestic authors. Identify common features and particular characteristics of each of them included in the content of this concept. The influence of foreign to domestic sources in the issue of the definition of the concept under consideration.