bluuebunny/crossref_metadata_2025 huggingface dataset:
PENDAMPINGAN PEMBELAJARAN BAHASA INGGRIS BAGI SISWA SD DAN SMP DI RUMAH BELAJAR GNL DI DESA KERTAUNGARAN
Authors: Budie Nugroho Muhammad Aprianto , Agustine Sheila
Published: February 2022

Program pengabdian berupa pendampingan bagi siswa Sekolah Dasar dan Sekolah Menengah Pertama dalam belajar Bahasa Inggris dilakukan bertujuan untuk membantu para siswa dalam belajar Bahasa Inggris dari rumah selama pandemic Covid-19. Pendampingan ini dilakukan dengan latarbelakang kesulitan-kesulitan para siswa dalam belajar Bahasa Inggris dan kesulitan orang tua dalam membimbing belajar Bahasa Inggris. Olah karena itu, program pengabdian ini disambut baik diantara orang tua yang tinggal di Perum Griya Nyansa Lestari. Terdapat 6 siswa yang tergabung dalam program pengabdian ini, jumlah siswa dalam program ini dibatasi dikarenakan protocol covid-19. Para siswa terlihat antusias dalam belajar Bahasa Inggris dalam program ini. Hal tersebut bisa dilihat dari kehadiran mereka selama pembelajaran. Program ini akan berlanjut selama para siswa dalam masa belajar di rumah.
PELATIHAN DESAIN GRAFIS SEBAGAI MEDIA DALAM KEMUDAHAN PENYAMPAIAN SYIAR ISLAM
Authors: Juanita Juanita , Supriyatno E.
Published: February 2022

Dakwah yang menarik dan kemudahan penyampaian syiar khususnya pada generasi muda sangat diperlukan. Penguasaan teknologi komputer khususnya desain grafis menjadi hal penting dalam era digital yang mendukung penyampaian syiar. Kemampuan pengurus Nasyiatul Aisyiyah Banyumas dalam desain grafis penting dalam syiar membidik generasi muda. Pelatihan desain grafis pada Pengurus Nasyiatul Aisiyah Kabupaten Banyumas memanfaatkan Microsoft Power Point agar lebih mudah dipahami. Metode yang digunakan melalui pelatihan/tutorial, praktek dan demonstrasi. Hasil pelatihan diperoleh manfaat pada peningkatan kemampuan desain grafis yang mendukung penyampaian syiar dan mendukung pekerjaan khususnya pada kegiatan organisasi.
Implementasi Undang-Undang Zakat No. 23 Tahun 2011 Tentang Pengelolaan Zakat (Studi Kasus LAZISMU Kota Bima)
Authors: Rasyad Al Fajar Muhammad , Jannah Miftahul
Published: February 2022

Penelitian ini merupakan penelitian kualitatif yang bertujuan untuk melihat implementasi undang-undang zakat nomor 23 tahun 2011 tentang pengelolaan zakat di LAZISMU Kota Bima. Penelitian ini mengambil 3 (tiga) responden yang terdiri dari satu perempuan dan dua orang laki-laki. Metode pengumpulan data menggunakan teknik wawancara, observasi dan dokumentasi. Hasil penelitian ini menunjukkan bahwa implementasi undang-undang zakat nomor 23 tahun 2011 di LAZISMU Kota Bima belum sepenuhnya terealisasi. Subjek merasa belum mampu merealisasikan karena ada beberapa kendala yang di hadapi, diantaranya seperti mental masyarakat yang konsumtif dan juga terkendala personil atau pengurus yang mengawasi program seperti itu.
我国省际间国际加工贸易的优势比较与问题分析
Authors: 朱 坚毅 , 陶 佳耀
Published: February 2022

国际分工合作是经济全球化的一大标志，它带来国际水平分工，也使国际垂直分工更加明显；而中国作为最大的发展中国家，在垂直分工领域发挥重要的作用，以加工贸易做为跟上全球步伐的主要方式。本文客观评价中国浙江省加工贸易现状，以广东、江苏两省作为辅助研究对象，对比三者在加工贸易占比、加工贸易增值率、企业出口状况等指标的差异，同时指出浙江省加工贸易发展的问题；通过省份间相互对比，系统地研究并调整各省的加工贸易策略，从而提出有针对性且契合实际的相关建议，以助益中国改善加工贸易结构、提升加工贸易地位和增强国际贸易影响力。
基于DEA-Malmquist指数的福建省行政效率研究
Authors: 林 小燕 , 林 欣
Published: February 2022

福建省位于我国华东地区，是我国对外开放程度较高的省份之一，先后获批平潭综合实验区、21世纪海上丝绸之路核心区、福建自由贸易区等“六区”，发展前景不容小觑；但近年来出现了部分城市资源浪费多、产出效能低和城市发展规模较小等的情况。本文从效率角度切入，运用DEA-Malmquist分析福建省9个城市2010~2019年的行政效率。通过数据分析结果显示，福建省省会福州市产出效率受其规模效率较低的影响较大，一级城市行政效率进步率低，而二级城市的产出效率长期维持在较高水平，不同年份间各市受到政策重视下的行政效率也有相应的提高。本文根据此结果，在资源分配、技术创新和管理体制上，为福建省的行政效率提升给予部分建议。
ON THE TECHNIQUE OF HEAT CALCULATION FOR UNDER-GROUND MINING WORKINGS IN THE PRESENCE OF ASCENDING HOT WATER FLOWS IN THE MASSIF
Authors: Lanchava Omar , Oniani Shurman Oniani
Published: February 2022

The problem of building a non-stationary temperature field round the working in the massif with ascending hot water flows is raised. The method of mathematical modelling is shown to be advisable in solving the problem. It is suggested that calculation of heat at the end of the working be done by determining the weighted average temperature of the transfer surface fey substituting the coefficient of heat irradiation a for the coefficient of non- stationary heat exchange Kt in the known calculation dependences.
ON THE TECHNIQUE OF DEFINITION OF THE HEAT MASS EXCHANGE NONSTATIONARY COEFFICIENTS IN WORKINGS
Authors: Lanchava Omar
Published: February 2022

The simple formulas for calculation of non-stationary factors heat and mass exchange in workings are offered. The dimensionless potentials, necessary for calculations, of carry of energy and mass are received by a method of mathematical modeling.
Demographic and Epidemiological Profile of Patients with Adult-onset Primary Open Angle Glaucoma in a Tertiary Niger-Delta Hospital, Nigeria
Authors: AA Onua, , CN Pedro-Egbe
Published: February 2022

Background/Objective: This was a prospective study of patients attending the Glaucoma Clinic at University of Port Harcourt Teaching Hospital, Nigeria and were diagnosed with adult-onset Primary Open Angle Glaucoma (POAG). The objective of the study was to identify and report the demographic and epidemiological characteristics and comorbid states of patients diagnosed with adult-onset POAG.
Materials and Methods: Clinical assessment of patients combined with findings from clinical records and interviewer-administered semi-structured questionnaire were used to obtain relevant data from the respondents between January and December 2021. Data collected included demographic data, ethnicity, comorbidity and family history of glaucoma.
Results: Eight hundred and fifty(n=850) POAG patients adult aged ≥40 years were recruited in this study. The mean age was 60.5 ± SD 10.1 years. The modal age group was 60-69 years. Seven hundred and seventy-two (n=777; 90.8%) had various forms of visual impairment. Five hundred and twenty-six (n=526; 61.9%) had positive family history of glaucoma in first degree relatives while 120 (14.1%) had positive family history of glaucoma in second degree relatives. Comorbidities associated with adult-onset POAG were cataract (44%), diabetes mellitus (30%) and systemic hypertension (26%).
Conclusion: Risk factors for adult-onset POAG in the Niger-Delta are similar to those reported in other black populations in Africa - impaired vision, positive family history of glaucoma, diabetes mellitus, systemic hypertension and cataract. Knowledge of patients’ demographic and epidemiological details are vital for early detection and treatment, thereby reducing the scourge arising from POAG in our population.

Keywords: Adult-onset POAG, demographic profile, epidemiological profile, Niger-DeltaRegion, Nigeria.
Analysis of the Effectiveness of the Application of Green Marketing to Typical Minang Restaurants with the Case of a Rumah Makan Sederhana Ringroad, Medan Branch
Authors: Putri Vanessa Aulia , Sinulingga Sukaria , Pujangkoro Sugiharto
Published: February 2022

This study aims to find out and analysis of the effectiveness of the application of green marketing to typical Minang Restaurants with the case of a Rumah Makan Sederhana Ringroad, Medan Branch. This research is a causal descriptive study with a quantitative approach. This research was conducted at Rumah Makan Sederhana Ringroad, Medan Branch. The sample in this study amounted to 100 people obtained using judgment sampling. This research uses multiple linear regression technique which consists of t test and F test. The results obtained in this study indicate that green marketing are product, price, place, and promotion have a positive and significant effect on customer awareness.

Keywords: Green Marketing, Product, Price, Place, Promotion, Customer Awareness.
Clinical Relevance of Cotinine and Nicotine Levels as Tobacco Exposure Biomarkers in Oral Cancer Patients
Authors: Jethva Disha D. , Rathod Bharati S. , Thobias Ashi R.
Published: February 2022

Introduction: Oral cancer is cause mainly due to habits of tobacco consumption and it is a major health hazard across the world. The death rate due to the disease is also very high. However, the association of tobacco exposure with stage of the disease and treatment outcome is not reported. Therefore, we assessed correlation between levels of tobacco exposure with the disease status and treatment outcome in oral cancer patients.
Materials and Methods: Urine samples were collected from enrolled pre-therapeutic oral cancer patients (N=96), healthy individuals with tobacco habits (N=19) and healthy individuals without tobacco habits (N=14). Urinary nicotine and cotinine levels were analyzed as indicators of tobacco exposure by HPLC methods. Data was statistically analyzed using the SPSS statistics version 20.0.
Results: Present study revealed that tobacco exposure levels were significantly higher in oral cancer patients and healthy individuals with tobacco habits as compared to healthy individuals without tobacco habits. Receiver Operating Characteristics (ROC) curve analysis revealed that tobacco exposure levels have a good discriminatory efficacy between healthy individuals without habit of tobacco and oral cancer patients as well as between healthy individuals without habit of tobacco and healthy individuals with habits of tobacco. Kaplan Meier survival curve analysis also revealed that patients who were having higher tobacco exposure levels at the time of diagnosis showed worse survival than patients who were having lower tobacco exposure levels.
Conclusion: Tobacco exposure levels could be a simple, non-invasive and cost effective prognostic biomarker for management of oral cancer.

Keywords: Tobacco exposure, Cotinine, Nicotine, HPLC, ELISA, Oral Cancer, Urinary biomarker.
Synthesis of 2,5-diphenyl-3,4-distyrylcyclopenta-2,4-dienone
Authors: Syeda Shaista Gillani Syeda Shaista Gillani , Munawar Ali Munawar Munawar Ali Munawar , Khalid Mohammed Khan and Ch Jamil Anwar Khalid Mohammed Khan and Ch Jamil Anwar
Published: February 2022

A series of 2,5-diphenyl-3,4-distyrylcyclopenta-2,4-dienone (3a-i) and 2,5-diphenyl-3,4-bis((1E,3E)-4-phenylbuta-1,3-dienyl)cyclopenta-2,4-dienone (5) have been synthesized by the condensation of various (1E,5E)-1,[-diarylhexa-1,5-diene-3,4-dione (1a-i) and (1E,3E,7E,9E)-1,10-diphenyldeca-1,3,7,9-tetraene-5,6-dione (4) with 1,3-diphenylpropan-2-one (2) using sodium hydride in dichloromethane. Electronic absorption and emission spectral studies have shown an efficient π-interaction due to the extended conjugation in the cyclopentadienones (3a-i, 5). The electronic excitation in the near UV-region (250-390 nm) to strong emission near (500-690 nm), allowing these to consider as light-harvesting species.
Synthesis and Biological Activities of Hydroxytyrosol Ester Derivatives
Authors: Hao Zang Hao Zang , Qian Xu Qian Xu , Luyun Zhang Luyun Zhang , Guangqing Xia Guangqing Xia , Jiaming Sun and Junyi Zhu Jiaming Sun and Junyi Zhu
Published: February 2022

A series of hydroxytyrosol (HT) derivatives were synthesized by modification of alcohol hydroxyl group of HT, twenty-five target compounds were obtained and characterized by NMR and HRMS. The antioxidant activities of those compounds were evaluated in three different assays. Except 3e and 3y, all other compounds demonstrated significant 2,2and#39;-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) free radical cation scavenging activity ranging from IC50 3.4 to 24.4 μM, which were more potent than L-ascorbic acid (IC50=24.8 μM). Compounds 3b-3d, 3f-3k, 3m-3x were better than Trolox (18.3 M). Moreover, the ferric reducing antioxidant power (FRAP) of all compounds were discovered to be more potent than L-ascorbic acid (40.7 mmol/g), except 3e, all other compounds (141.5-202.1 mmol/g) were better than Trolox (94.7 mmol/g). Compounds 3a-3d, 3f-3j, 3l-3m, 3o, 3q, 3t, 3v-3y exhibited more potent hydroxyl radical scavenging activity (IC50=245.1-475.1 M) than L-ascorbic acid (554.4 M) and Trolox (500.4 M). Compounds 3q, 3t and 3y exhibited more potent -Glucosidase inhibition activity (39.1-52.4 M) than Acarbose (60.9 M). Compounds 3a, 3d, 3f-3m, 3s-3t, 3v-3y showed some acetylcholinesterase inhibition activities, compounds 3a, 3d, 3f-3j, 3l-3m, 3o-3p, 3s-3t, 3w showed some butyrylcholinesterase inhibition activities.
Determination of Bendiocarb Insecticide by Reverse Flow Injection Analysis Using a Solid-Phase Reactor Containing Micro PbO2, Nano PbO2 and Grafted SiO2 - PbO2 Immobilized
Authors: Malik H Alaloosh Alamri Malik H Alaloosh Alamri , Sadeem Subhi Abed and Abdulkareem M A Alsammarraie Sadeem Subhi Abed and Abdulkareem M A Alsammarraie
Published: February 2022

Bendiocarb (BEN) is an acutely toxic carbamate insecticide which used in public places and agriculture, it is also effective against a wide range of nuisance and disease vector insects. A new rapid and sensitive reverse flow injection spectrophotometric procedure coupled with on-line solid-phase reactor is designed in this article for the determination of BEN in its insecticidal formulations and water samples, by using three different solid-phase reactors containing bulk PbO2 (B-SPR), PbO2 nanoparticles (N-SPR) and grafted nanoparticles of SiO2-PbO2 (G-SPR) immobilized on cellulose acetate matrix (CA). This method of oxidative coupling is based on alkaline hydrolysis of the BEN pesticide, and then coupled with N,N dimethyl-p-phenylenediamine sulphate (DMPD) to give a blue color product which measured at λmax 675 nm. It worth to mentioned that under optimal conditions, Beer’s law is obeyed in the range of 1-175 μg mL-1 for B-SPR and 0.25-70 μg mL-1 of BEN for both N-SPR and G-SPR respectively within limit of detection (LOD) of 0.931, 0.234 and 0.210 μg mL-1 for B-SPR N-SPR and G-SPR respectively. The surface methodology of the solid phase was also investigated by using atomic force microscopy.
Beneficiation Study on Low-Grade Graphite Ore of Shounter Valley, Azad Kashmir, Pakistan
Authors: Muhammad Arif Bhatti Muhammad Arif Bhatti , Kamran Raza Kazmi Kamran Raza Kazmi , Samreen Zahra Samreen Zahra , Ansar Mehmood and Rashid Mehmood Ansar Mehmood and Rashid Mehmood
Published: February 2022

A low-grade graphite ore originating from Kael area, Shounter Valley, Azad Kashmir, assaying 8.90% graphite content was upgraded by froth flotation technique to produce a commercial grade graphite concentrate. Mineral phases present in the ore were identified by using X-ray diffraction (XRD) technique. The variables of flotation process such as particle size of the feed, pH of the pulp, % solids of the pulp, speed of impeller, type and quantity of collecting and frothing agents, conditioning time and froth collecting time were optimized to get maximum grade and recovery of graphite mineral. The pH of the pulp was adjusted with sodium carbonate. Kerosene oil was used as collector while pine oil as frother respectively. Sodium silicate was employed as depressant. The grade of the final graphite concentrate produced was 85.80% C with overall recovery of 86.00%. Its surface morphology was studied using SEM-EDX technique while grain size by laser particle size analyzer.
Development and Validation of Novel GC-FID Method for Simultaneous Quantification of Paracetamol and Caffeine in Formulations
Authors: Imtiaz Hussain Imtiaz Hussain , Yawar Baig Yawar Baig , Sara Naveed Sara Naveed , Muhammad Imran Khan Muhammad Imran Khan , Hafiz Shoaib Sarwar Hafiz Shoaib Sarwar , Asad Ullah Madni and Muhammad Farhan Sohail Asad Ullah Madni and Muhammad Farhan Sohail
Published: February 2022

The advancements in analytical techniques have enabled the development of highly sensitive and accurate methods for the identification of materials up to trace levels using microliter of sample. A highly sensitive and novel GC-FID method has been developed and reported herein for the simultaneous quantification of paracetamol (PCM) and caffeine (CAF) in samples up to trace levels. The method was validated as per ICH guidelines for its sensitivity, linearity, robustness, inter and intra-day variations, limit of quantification (LOQ), limit of detection (LOD), matrix effect, carryover, precision, and accuracy. The LOD of PCM and CAF were determined to be 100 ppm and 10 ppm whereas, LOQ of PCM and CAF were found to be 300 and 30 ppm respectively. The method was applied to quantify PCM and CAF in marketed tablets and dissolution samples of the tablets, which showed highly precise and accurate quantification of PCM and CAF. Moreover, the GC-FID method was compared with reported HPLC method which suggested the superiority of GC-FID method in performance and sensitivity. In short, the newly developed GC-FID method showed sensitivity and selectivity for PCM and CAF estimation and can be adopted as an efficient method for various applications.
Synthesis, Bacterial Biofilm Inhibition and Hemolytic Activity of 4-Chloro-N-(dimethylphenyl)butamide regio-isomers
Authors: Muhammad Athar Abbasi Muhammad Athar Abbasi , Muhammad Shawal Hassan Muhammad Shawal Hassan , Aziz ur Rehman Aziz ur Rehman , Sabahat Zahra Siddiqui Sabahat Zahra Siddiqui , Syed Adnan Ali Shah Syed Adnan Ali Shah , Muhammad Shahid Muhammad Shahid , and Khalid Mohammed Khan and Khalid Mohammed Khan
Published: February 2022

The goal of this work was to synthesize some 4-chloro-N-(dimethylphenyl)butamide regio-isomers starting from dimethylated phenylamines and to examine their biofilm inhibition against Staphylococcus aureus and Escherichia coli strains along with hemolytic activity. The synthetic approach for the synthesis of regio-isomers involved the reaction of 4-chlorobutanoyl chloride (1) with three different dimethylphenylamines (2a-c) in alkaline medium under vigorous shaking for 1-2 h under dynamic control of pH ranging from 9-10 to obtain the final products, 4-chloro-N-(dimethylphenyl)butamides (3a-c). The structural confirmation of these products was accomplished using IR, 1H-NMR, 13C-NMR and CHN analysis data.
Paper-Based Analytical Device for Rapid Naked-Eye Detection of Sulfide in Water Samples
Authors: Lingzhi Zhao Lingzhi Zhao
Published: February 2022

This paper describes the development of a low-cost paper-based colorimetric analytical device for the accurate and rapid determination of sulfide. Under optimized conditions, Na2S was dropped in the uptake zone I and the probe in the uptake zone II, they converged to the detection zone via capillary force and formed an intense pink resorufin. Sulfide can be quantified based on the average color intensity values of the product “free resorufin”. The color intensity is recorded using a camera phone, and quantification was made using Adobe Photoshop. The as-developed analytical device detected sulfide in the range of 5–400 μM (R2 = 0.982) with the limit of detection (LOD) 1 μM, and was successfully applied in sulfide assay in spiked water samples including tap water and simulated waste water. Colorimetric results from the proposed paper-based colorimetric analytical device were consistent with that from methylene blue (MB) method.
Synthesis and Characterization of Zirconium Metal Complexes Derived from Benzene-1, 4-dicarboxylic acid
Authors: Hafiz Muhammad Arshad Hafiz Muhammad Arshad , Shazia Khurshid Shazia Khurshid , Shahzad Sharif Shahzad Sharif , Muhammad Ali Muhammad Ali , Muhammad Dilshad Muhammad Dilshad , Muhammad Ajmal Muhammad Ajmal , Sadaqat Ali and Hafiz Ishfaq Ahmad Sadaqat Ali and Hafiz Ishfaq Ahmad
Published: February 2022

Amongst organo-metallic frameworks (OMFs), the metallic framework having Zirconium metal indicate fascinating structural properties and excellent stability. Such organo-metallic frameworks (OMFs) function as a potential material for practical application. Even though these particular organo-metallic frameworks are in the early developmental stage but considerable advancements have been carried out recently. We studied the characterization of zirconium-based organo-metallic frameworks. We built Zr-based OMFs by four different synthetic ways. Initially, upgraded preparation under green and commercially feasible conditions has been carried out by modifying Zr-OMFs. Zirconium based OMFs having different structures are then classified and explained based on various organic ligands and zirconium-based secondary building units. We have synthesized the zirconium metal complexes; they have been characterized on the bases of FT-IR and CHNS analyzer. FT-IR results show binding of metal with the Benzene-1, 4-dicarboxylic acid [C6H4 (COOH) 2]. Zirconium metal can bind with the organic substances for the construction of a variety of complexes. From my research work, it is concluded that zirconium metal forms a polymeric complex with terephthalic acid. In which oxygen atoms of Terephthalic acid form bridging structure with the zirconium metal. Our study based on a particular type of OMF is likely expected to present guidance for in-depth exploration of OMFs towards practical applications. It is concluded that the metal-organic frameworks (MOFs) of zirconium metal have many applications in the field of chemistry, biology and other numerous fields of science
Synthesis, Crystal Structure and Antimicrobial Activity of Poly [bis-and#181;-3,5-dinitro-2-oxidobenzoato) (py) Cu II]
Authors: Fouzia Chang Fouzia Chang , Najma Memon Najma Memon , Shahabuddin Memon Shahabuddin Memon , Muhammad Naeem Ahmed Muhammad Naeem Ahmed , Muhammad Nawaz Tahir Muhammad Nawaz Tahir , Abdul Sattar Chang Abdul Sattar Chang , Muhammad Hassan Agheem Muhammad Hassan Agheem
Published: February 2022

A novel Poly [bis-and#181;-3,5-dinitro-2-oxidobenzoato) (py) Cu II]/(C12H7CuN3O7) was synthesized by a self assemble method at room temperature. The molecular structure was determined by single-crystal X-ray analysis. The compound crystallizes in the monoclinic system, space group P 2 1/c with lattice parameters of a = 10.2143, b = 5.1651 and c = 26.608, α = 90, β = 99.720, γ = 90, Z = 4, V = 1383.60 (18) and#197;3.Pore size depicted from single crystal XRD data was 47and#197;. The central metal atom Cu (II) is coordinated with oxygen of carboxylates group and nitrogen atom of pyridine. The coordination polyhedron posses square pyramidal geometry is manifested by the N— Cu—O angle of 90o. The structure is composed of monomeric coordination units with the central copper (II) ion is not occupying a centre of symmetry.
Risk analysis of restrictive factors for fast-track hip arthroplasty - a retrospective study of 1138 patients
Authors: Radetzki Florian , Körber Tina , Wohlrab David , Delank Karl Stefan
Published: February 2022

Fast track programs have been introduced to reduce perioperative complication rates and to quickly reintegrate the patient into everyday life. The aim of this retrospective case-control study was to identify patient characteristics and patient-independent factors that influence fast track programs in hip arthroplasty. A total of 1138 patients were examined. A hospital stay of more than seven days was used to define the case group. In addition to the causes for the longer hospitalisation, age, sex, BMI, chronic nicotine and alcohol abuse, ASA score, surgical duration, anaemia and blood transfusion as well as concomitant diseases were assessed. The statistical analysis included two-sample t-test, chi-square test and logistic regression analyses. An 95% confidence interval was calculated (p<0.05). 16.9% of patients could not leave the hospital on the seventh day. The main causes were delayed wound healing (69.4%), increased CRP (43.0%>100 mg/l), and internal complications (19.7%). At a mean of 69.2 ± 10.7 years, the age of the case group was significantly higher than that of the control group, which had a mean of 63.3 ± 10.3 years (p<0.001). Cardiac comorbidities (p<0.001), BMI (p=0.023), and alcohol consumption (p<0.001) increased the risk for longer hospitalisation. Significant patient-independent factors were duration of the surgery (p<0.001) and transfusion (p<0.001). Successful application of fast-track hip arthroplasty is possible for every patient. However, longer hospi- talisation and delayed discharge must be taken into account for patients with advanced age, cardiac comorbidities, alcohol consumption, and high BMI.
Length of hospital stay following hip fracture and risk of 30 and 90 day mortality in a United Kingdom cohort
Authors: Sheikh Hassaan Q. , Alnahhal Amro , Aqil Adeel , Hossain Fahad S.
Published: February 2022

A recent study identified a length of stay (LOS) of 10 days or less following hip fracture is associated with increased risk of 30-day mortality. This effect has not been previously studied for 90-day mortality or in the United Kingdom (UK). Our aim was to investigate the effect of LOS on 30-day and 90-day mortality following hip fracture in a UK population. In this single-centre study, we retrospectively identified consecutive patients with a hip fracture from the National Hip Fracture Database over 3 years. We excluded patients who died as inpatient during their index admission. The main end-points were 30-day and 90-day mortalities and risk factors for these were examined using stepwise univariate and multivariate Cox regression analyses. Of 1228 patients, mortality at 30-days was 1.2% (15 patients) and 7.8% (96 patients) at 90-days. Mean LOS was 24 days and a total of 206 patients had a LOS of 10 days or less. Following cariate analysis, the highest risk factor for 30-day mortality was a LOS of 10 days or less with a hazard ratio of 7.26 (95% confidence interval 2.56-20.51). Other risk factors for 30-day mortality included increasing age, male gender and chest infection. A LOS of 10 days or less was not associated with increased mortality at 90-days. A short LOS was associated with higher risk of early mortality. We recommend that hip fracture patients be fully rehabilitated prior to discharge to reduce the risk of early mortality.
Platelet-rich plasma vs platelet-rich plasma plus hyaluronic acid for haemophilic knee arthropathy treatment
Authors: Landro María Eulalia , Daffunchio Carla , Cambiaggi Guillermo , Galatro Gustavo , Caviglia Horacio
Published: February 2022

Repeated joint bleeding leads to chronic synovitis, cartilage damage and bone alterations which result in haemophilic arthropathy and are associated with pain, functional impairment and poor quality of life. There are evidence that Hyaluronic Acid (HA) and Platelet-rich Plasma (PRP) have different mechanisms of action in the treatment of arthropathy for this reason we decided to use both components. The aim of this study is to compare, the efficacy, safety and duration of a single intra-articular injection of PRP against PRP+HA for pain, bleeding episodes and joint health, in the same patient with bilateral hemophilic knee arthropathy. Twenty-one men patients (42 knee joints) were treated with intra- articular injections of PRP or PRP+HA. All of them were haemophilia type A severe. The mean age was 36.6 years (21-72). All patients were evaluated for: Haemophilia Joint Health Score (HJHS), pain (VAS), the number of bleeding episodes (BE) in the last 30 days, before treatment, at three and six months after treatment. Statistically significant improvement were shown for both knee joints at three and six months after treatment for VAS and BE (P < 0.00001). The HJHS score did not significantly improve for either knee in the 6-month period after injection. A single PRP or PRP+HA injection is safe and effective in treating haemophilic arthropathy of the knee for up to 6 months follow-up, reducing pain, bleeding episodes and delaying total knee arthroplasty.
Associations between biomarkers and histological assessment in individual animals in a destabilization of the medial meniscus (DMM) model of osteoarthritis (OA)
Authors: Choi Seon Young , Rhim Jiheon , Han Woo-Jung , Park Hyunjin , Noh Jin-Wook , Han Jungwon , Ha Chul-Won
Published: February 2022

To date, the use of biomarkers for assessing individual severity of osteoarthritis (OA) is limited, and the correlation of histological scores with biomarkers for individual animals in the destabilization of the medial meniscus (DMM) model of OA has not been well investigated. Accordingly, this study investigated how well representative biomarkers in the DMM model reflected specific changes in individual animals.

Rats were randomly divided into the OA group and the sham group. OA model was established by destabilization of the medial meniscus (DMM). After 2,4,6,8,10 and 12 weeks (n=14, each week), the concentrations of CTXII, COMP, C2C, and OC in serum were measured, and cartilage degeneration, osteophytes, and synovial membrane inflammation, typical of OA, were scored using Osteoarthritis Research Society International (OARSI) scoring system. Additionally, the correlation between each biomarker and the specific changes in osteoarthritis was analyzed for individual animals using the Generalized Estimating Equation (GEE).

Statistical analysis showed a low correlation between CTXII and osteophyte score of the medial femur (coefficient = -0.0088, p= 0.0103), COMP and osteophyte score of the medial tibia (coefficient = -0.0911, p= 0.0003), and C2C and synovial membrane inflammation scores of the medial femoral (coefficient = 0.054, p= 0.0131).

These results suggest that representative OA bio- markers in individual animals in the DMM model did not reflect histological scores well.
The effectiveness of a Botulinum Toxin A infiltration in the management of bicipital cramps after arthroscopic biceps tenotomy
Authors: Torrekens Marieke , Vanmierlo Bert , Van Isacker Tom
Published: February 2022

A challenging complication of arthroscopic biceps surgery is the persistent painful cramping of the biceps. There is a paucity of data upon nonsurgical treatment of this debilitating complication. We propose an intramuscular injection of botulinum toxin A (BTX-A) for painful bicipital cramping after tenotomy of the long head of the biceps brachii tendon (LHBT). Ten patients with a painful Popeye sign after tenotomy of LHBT, were treated with intramuscular injection of 100 IU of BTX-A. Mean patient age was 56 years and mean time from surgery to infiltration was 317 days. The Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) score was obtained. Pain was objectified by a visual analogue scale (VAS). Patient satisfaction was described as excellent, good, satisfactory, or poor, three and six months after injection. Mean VAS prior to infiltration was 6.8 and decreased significantly to 2.6 at follow-up. Mean QuickDash was 54.04 prior to infiltration and decreased to 19.84 at follow-up. Patient satisfaction was excellent in 9 and good in 1 patient. We report a significant pain reduction and functional improvement following BTX-A infiltration as treatment of painful bicipital cramping after tenotomy of LHBT.
SKRINING FITOKIMIA EKSTRAK CARICA PAPAYA RADIX, PIPER ORNATUM FOLIUM DAN NEPHELIUM LAPPACEUM SEMEN ASAL KALIMANTAN SELATAN
Authors: Zaini Muhammad , Shofia Vivi
Published: February 2022

Penyakit Diabetes Mellitus merupakan penyakit dengan prevalensi tinggi dan menduduki peringkat 10 besar di dunia termasuk di Indonesia. Permasalahan besar yang dihadapi dunia kesehatan dewasa ini adalah Diabetes Mellitus tidak bisa disembuhkan secara total dengan obat antihiperglikemik konvensional. Penelitian perlu dilakukan dalam hal menelusuri potensi bahan alam yang biasa digunakan oleh masyarakat Kalimantan berdasarkan skrining fitokimia dari beberapa tumbuhan yang secara empiris digunakan sebagai antidiabetes yaitu Carica papaya radix (CPR), Nephelium lappaceum semen (NLS) dan Piper ornatum folium (POF). Tumbuhan obat yang diperoleh dilakukan ekstraksi maserasi dan diidentifikasi golongan senyawa dan profil kromatografinya.Kegiatan penelitian ini meliputi: 1) Pengambilan sampel tumbuhan,2) Pembuatan simplisia uji, 3) Pembuatan ekstrak etanol tumbuhan, 4) Uji kualitatif kandungan kimia tumbuhan, dan 5) Identifikasi secara kromatografi lapis tipis.

Hasil dari penelitian dipilih dan dilakukan pengujian terhadap 3 ekstrak yaitu Carica papaya radix, Nephelium lappaceum semen dan Piper ornatum folium. Ekstrak Carica papaya radix diduga mengandung senyawa alkaloid (Rf : 0,53), saponin (Rf : 0,93), flavonoid (Rf : 0,38 ; 0,75) dan tanin (Rf : 0,52 ; 0,88). Ekstrak Piper ornatum folium diduga mengandung senyawa saponin (Rf : 0,89), steroid (Rf :0,20 ; 0,42) dan tanin (Rf : 0,52 ; 0,71 ; 0,85). Ekstrak Nephelium lappaceum semen menunjukkan hasil positif terhadap keberadaan senyawa alkaloid (Rf : 0,65 ; 0,82), flavonoid (Rf : 0,83) dan tanin (Rf : 0,79 ; 0,92).
Penatalaksanaan Fisioterapi untuk Menurunkan Tekanan Darah pada Lansia yang Mengalami Hipertensi dengan Metode Slow Deep Breathing dan Swedish Massage Therapy di Desa A. Yani Pura
Authors: Pertiwi Aniesa Nur Laily , Nafiah Nafiah Nafiah , Oktaviani Yulisha Eva
Published: February 2022

Hipertensi merupakan kondisi tekanan darah yang terus meningkat melebihi 120/80 mmHg dengan selang waktu yang lama walaupun orang tersebut dalam keadaan istirahat. Tujuan penelitian ini adalah untuk mengetahui penatalaksanaan fisioterapi pada lansia yang mengalami hipertensi dan apakah ada penurunan tekanan darah setelah diberikan intervensi fisioterapi berupa slow deep breathing (SDB) dan swedish massage therapy (SMT). Penelitian ini menggunakan metode case study dengan menggunakan satu sampel pasien hipertensi. Treatment dilakukan sebanyak 12 kali dalam kurun waktu 4 minggu yang diukur sphygmomanometer. Hasil penelitian yang didapatkan setelah dilakukan evaluasi yaitu adanya penurunan tekanan darah pada kondisi hipertensi. Berdasarkan hal tersebut, SDB dan SMT efektif digunakan dalam menurunkan tekanan darah pada kondisi hipertensi. Disarankan kepada peneliti selanjutnya agar dapat menggunakan dosis yang lebih singkat dan melakukan pemeriksaan tekanan darah secara rutin.
Barnesentrering og risikoorientering i det norske barnevernet: Utfordringer i profesjonell praksis i saker med alvorlig vold eller omsorgssvikt
Authors: Aadnanes Margrete , Syrstad Ellen
Published: February 2022

I denne artikkelen utforsker vi hvordan barnevernets risikoorientering og barnesentrering kan få utilsiktede konsekvenser for profesjonell praksis. Alvorlige barnevernssaker innebærer utfordrende og vanskelige vurderinger, hvor de etiske dilemmaene blir ekstra krevende. Vi undersøker hvordan økt fokus på avdekking av alvorlig vold og omsorgssvikt har virket inn på barnevernets arbeid, på hvilken måte foreldre opplever barnevernet som problemfokusert i samarbeidet og hvordan dette svekker tilliten til fagpersoner som skal hjelpe dem. I en tid hvor barnevernet er utsatt for sterk kritikk både internasjonalt og nasjonalt, og hvor denne kritikken retter seg mot barnevernets manglende fokus på gjenforening og tilrettelegging for samvær mellom barn og foreldre, ønsker vi å bidra til en kritisk reflekterende diskusjon om hvordan den politiske, sosiale og internasjonale sammenhengen som det norske barnevernet inngår i, virker inn på faglige dreininger i praksis. Våre analyser bygger på empiri fra to Ph.D.-prosjekter som omhandler henholdsvis barn som opplever vold i nære relasjoner, og oppfølging av foreldre som er fratatt omsorgen for sine barn.
English abstract
Child centring and risk aversion in Norwegian Child Welfare Services: Challenges in professional practice in cases of child abuse and maltreatment
In this paper, we explore how child-centric practice and focus on risk aversion in Norwegian Child and family Welfare Service (CWS) may have unintended consequences for professional practice. Serious child welfare cases involve challenging and difficult assessments, where the ethical dilemmas become extra demanding. We examine how the focus on uncovering severe violence and neglect has affected CWS’s practice, how parents experience the CWS as problem-focused and how this impairs the trust in the professionals. Norwegian CWS is currently experiencing heavy criticism, both nationally and internationally. The critique is directed towards lack of focus on the children reuniting with their parents. In this paper, we aim to critically discuss how the political, social and global context impacts professional directions in the Norwegian CWS’s practice. Our analysis builds upon empirical findings from the authors’ two Ph.D.-studies dealing with children’s experiences of child abuse and maltreatment and parents experiences of losing their children to public care.
Upaya Peningkatan Produksi Perikanan Tangkap di PPP Dobo Kabupaten Kepulauan Aru Dalam Mendukung Maluku Sebagai Lumbung Ikan Nasional
Authors: Rumadan Galib , Ernaningsih Dwi , Telussa Riena F
Published: February 2022

Pembangunan Provinsi Maluku sebagai Lumbung Ikan Nasional dengan estimasi target produksi 750.000 ton/tahun memberikan peran strategis pada Pelabuhan Perikanan Pantai Dobo Kabupaten Kepulauan Aru yang merupakan salah satu wilayah paling produktif dalam sektor perikanan tangkap. Namun, mengalami penurunan produksi dalam beberapa tahun terakhir. Penelitian ini bertujuan untuk menentukan, menganalisis dan menetapkan variabel prioritas dalam upaya meningkatkan produksi perikanan tangkap. Penelitian dilaksanakan pada bulan April hingga Agustus 2021 di PPP Dobo Kabupaten Kepulauan Aru Provinsi Maluku. Data primer dikumpulkan melalui survei dan wawancara kepada 5 orang pengelola pelabuhan dan 3 orang nelayan yang dipilih secara purposive sampling. Data yang dikumpulkan berupa faktor-faktor yang berpengaruh terhadap produksi perikanan tangkap yaitu kapal, alat tangkap, dan nelayan.  Data selanjutnya dianalisis mengunakan Analytical Hierarchy Process. Hasil penelitian menunjukkan bahwa nilai kepentingan tertinggi pada pembinaan nelayan sehingga direkomendasikan sebagai alternatif yang tepat untuk neningkatkan produksi perikanan tangkap di PPP Dobo Kabupaten Kepulauan Aru.
Flipped classroom methodology in students at technological institutes
Authors: Betancourt Luis Aníbal Alonso , Cabezas Miguel Alejandro Cruz , González Vilma Maribel García , Mena Marcia Liliana Baño , Aguilar Daisy Karina Silva
Published: February 2022

This study aimed to explore a methodology for the professional teaching of students of technological institutes (whether it is middle and/or higher level) in inverted classrooms. It is based on the alternative and interactive method of content appropriation based on projects, which integrate the face-to-face modality with the virtual modality. The scientific novelty lies in the establishment of a dynamic that integrates the face-to-face modality with the virtual modality, based on the link between academic, labor, and research. Document review methods, the system approach, direct observation in the field, the pedagogical pre-experiment, and the Chi-square statistical test (X2) are used. As a result, the favorable impacts on the development of professional skills were observed in a sample of 100 students of the Mechanics career at the University of Holguín, Cuba, with the application of the result. It can be generalized in any worker training center with flexibility and adaptability to the characteristics of these entities.
Student experience: 10 things I know for certain
Authors: Kinash Shelley
Published: February 2022

Through an autoethnographic account of a university career journey, this paper addresses ten key themes in higher education. These are the ten principles which matter most in education. Attending to the quality of these elements will ensure that the vast majority of students have an excellent experience and that by virtue of completing their education, graduates will have the foundations they require to achieve their career goals. High quality universities keep the focus on their students, and students are welcomed and encouraged as agentic, contributing citizens, who will lead communities forward through graduate careers. The student experience is streamlined, minimising expectations of students beyond their coursework. Whereas the educators make or break the experience for the students, there are numerous other education-focussed staff roles in universities and staff must work in-concert. Universities must continue to apply digital innovation to improve processes such that student experience mechanisms, such as enrolment, are efficient and user-friendly, so that students can expend their cognitive energies on learning rather than navigating convoluted processes. One size does not fit all and university education must be delivered in ways which meet the needs and expectations of diverse student cohorts, and personalised in bespoke and supported ways for individual students. Universities seek to enhance and continuously improve student experience, engagement and retention.
Factors affecting effective online teaching transition in Asian universities during COVID-19
Authors: Das Rajib , Meredith David
Published: February 2022

Educational institutions, especially the higher education institutions in Asian countries such as Bangladesh and Thailand, have had to stop face-to-face educational activities during the period of COVID-19 pandemic. Online classes have been the only alternative to carry on academic activities. Teachers were suddenly compelled to transition their teaching and learning methodology from a face-to-face to an online model. Employing a quantitative research method, this study identifies factors in teacher’s effective transition for successful online teaching. A total of 68 teachers experienced in higher education in Bangladesh, Thailand, India and Indonesia were interviewed by a structured questionnaire. The instrument was scrutinized and approved by a panel of 5 expert educators in higher educational institutes in both Bangladesh and Thailand. The statistical analysis indicated that professional training, students’ performance evaluation, cheating concerns in exam perceived by teachers, infrastructure difficulties, lack of students’ technological knowhow and difficult online classroom management influenced success in online teaching. A set of inspectional recommendations has been made that might be utilized in policy making by the educational policy makers, institutional authorities and by the practising teachers for designing effective procedures of online teaching and learning.
Incidencia y severidad de Mal de Panamá (Fusarium Sp) en Guineo (Musa balbisiana ABB)
Authors: Castillo Arévalo Trinidad
Published: February 2022

El cultivo de las musáceas (Musaceae) en Nicaragua, ha sido un rubro de buena rentabilidad y aceptables índices de producción, representa un producto promisorio en el departamento de Rivas y en algunas zonas del país. Los ingresos de este cultivo se han visto amenazados por esta enfermedad (Mal de Panamá) que afecta a la planta y sus frutos. Con el objetivo de contribuir al conocimiento científico, a través de un estudio de los principales síntomas y condiciones ambientales de Mal de Panamá, asociados al cultivo de guineo, se realizó esta investigación de marzo del 2014 a marzo del 2015, en un sistema Taungya, para describir los principales síntomas de daño y calcular la incidencia, severidad y ABCPE (Área Bajo la Curva de Progreso de la Enfermedad) de Mal de Panamá en cultivo de guineo. La recolección de los datos del patógeno se hizo a través de monitoreos visuales en campo y diagnóstico de laboratorio de la Universidad Nacional Agraria. El muestreo se realizó semanal, para la prueba de campo se tomaron muestras de plantas enfermas o sintomatológicas del agente causal, se procedió a su eliminación. Como resultado del estudio se identificó Fusarium sp asociado al cultivo de guineo. De manera general la incidencia de este agente causal reflejó un comportamiento similar en los bloques de guineo (0.53 %) y caoba (0.61 %), seguido de melina (0.36 %), en los bloques de cedro, pochote, roble y teca los síntomas de marchitamiento vascular se presentaron en porcentajes de 1.12 % a 1.80 %.
Securing Rights, Combatting Climate Change: How strengthening community forest rights mitigates climate change
Authors:   Rights and Resources Initiative,   World Resources Institute
Published: February 2022

The international community agrees on the urgent need to reduce greenhouse gas emissions from deforestation and forest degradation. With 13 million hectares of forest cleared every year, such efforts are critical to curbing climate change before it reaches a dangerous tipping point. But we are missing a vital opportunity to combat climate change—strengthening the land and resource rights of Indigenous Peoples and local communities whose well-being is tied to their forests. This publication analyzes the growing body of evidence linking community forest rights with healthier forests and lower carbon dioxide emissions from deforestation and forest degradation. It presents a compelling case for expanding and strengthening community forest rights based on evidence drawn from comparative studies, advanced quantitative research, case studies, and original deforestation and carbon analyses by the World Resources Institute. The findings center on examples from 14 forest-rich countries in Latin America, Africa, and Asia. Together, these countries contain about 323 million hectares of government-recognized community forest —68 percent of the estimated total in all low- and middle-income countries—as well as large areas of community forests without legal or official recognition. Our analysis focuses on the links between legal community forest rights (or lack thereof), the extent of government protection of those rights, and forest outcomes.
Mai-Ndombe: Will the REDD+ Laboratory Benefit Indigenous Peoples and Local Communities?
Authors: Gauthier Marine
Published: February 2022

This study aims to assess the cumulative risks and impacts of all REDD+ initiatives in Mai-Ndombe on the rights and subsistence of local communities and Indigenous Peoples, using existing tools while taking into account gray areas of the REDD+ process. Findings come from existing project documentation, field studies conducted in recent years, and a series of interviews with REDD+ stakeholders in Mai-Ndombe. The study provides a mapping of all existing and planned REDD+ initiatives in the province, as well as a cross-cutting contextual analysis of risks which connects REDD+ to human rights. This is followed by an assessment of these initiatives’ cumulative impacts as well as of national and project strategies to address and reduce risks. It thus offers a perspective on the link between the accumulation of REDD+ initiatives and conflicts at different scales.
MARKETING STRATEGY IMPLEMENTATION, SYSTEM MANAGERS ADAPT AND RESHAPE BUSINESS STRATEGY FOR PANDEMIC
Authors: Sulasih Sulasih , Adawiyah Wiwiek Rabiatul
Published: February 2022

Contingency theory explains that the environment has a significant impact on an organization. Related to the current environmental conditions in which the whole world, including Indonesia, is experiencing a crisis due to the pandemic, entrepreneurs who can survive the uncertain economic conditions due to the pandemic outbreak are certainly entrepreneurs who can adapt to environmental changes just think smart, creative, and innovative. The research method used qualitative research approach with the survey method by generalizing the results of exploring in-depth data on SMEs in Banyumas. This study's purpose based on previous research's advice was to explore the use of technology in SMEs to ensure business continuity during the pandemic and to determine strategies for SME problems in Indonesia during the pandemic based on previous research results. Entrepreneurs are advisedly managed intelligently by determining a  strategy related to marketing strategies and the business management system adapted to the changing environment to increase sales. Entrepreneurs should change conventional marketing systems and modernize by utilizing technology to run business activities. Several strategies for entrepreneurs to survive this pandemic situation can utilize digital technology and improve products, services, and CRM. Notably, management must be able to adapt by making several policies to control the business.