bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategi Komunikasi Iklan dalam Masa Pandemi Covid-19 (Iklan Campaign KFC Stay At Home)
Authors: Sasmito Syam Alam , Santosa Hedi Pudjo
Published: March 2022

Permasalahan peneletian ini berawal dari sebuah perusahaan waralaba seperti KFC ini mendapati sebuah tantangan, dan dampak pada regulasi - regulasi masa pandemi ini. Tampaknya redaksi restoran ini juga telah menerapkan protokol kesehatan. Dalam penulisan ini media yang akan di observasi dari perusahanan KFC mempunyai sebuah kampanye iklan yang dibuat untuk dalam masa pandemi ini. lebih tepatnya pada kisaran bulan Mei, 2020. Penelitian ini menggunakan pendekatan kualitatif studi literatur, karena suatu kasus ini sebagai suatu event unik dalam dunia periklanan dan menyambungan dalam keterusan untuk mempertahankan suatu bisnis dengan komunikasi krisis, visual dan pemasaran. Tercipta nya sebuah kepercayaan, solidaritas dan kemauan untuk maju bersama. Penelitian ini menunjukkan dimana komunikasi dalam pemasaran dan merek dapat berubah dan bereaksi terhadap kelalaian dalam situasi kritis dengan iklan. Dapat diambil bahwa compasionate act dan pengambilan konten, dan sosial media sebagai salah satu cara strategic untuk mengkomunikasikan dengan bantuan social media, hal ini menjadi suatu booster yang cepatIklan seperti ini adalah salah satu cara strategic komunikasi dalam pandemi atau menghadapi sebuah tantangan. jadi berharap merek seperti ini akan terus menghasilkan dan mengkalibrasi sumber daya untuk berbisinis, memasarkan, dan komunkasi secara sehat
Efektivitas Penggunaan Aplikasi Mobile JKN Dalam Mengurangi Antrian
Authors: Prasetiyo Ryan Aldi , Safuan Safuan
Published: March 2022

Perkembangan Teknologi Informasi dan Komunikasi saat ini semakin berkembang. Demikian juga halnya dalam jaminan kesehatan dibutuhkan Penerapan Teknologi Komunikasi dan Informasi. Aplikasi mobile JKN merupakan suatu bentuk transformasi digital model bisnis BPJS Kesehatan yang semula berupa kegiatan administratif dilakukan di Kantor Cabang atau Fasilitas Kesehatan, ditransformasi ke dalam bentuk aplikasi yang dapat digunakan oleh peserta dimana saja dan kapan saja serta diharapkan dapat mengurangi antrian di setiap Kantor Cabang BPJS Kesehatan. Melihat dengan sudah berjalannya aplikasi ini dapat diketahui apakah penggunaan aplikasi mobile JKN sudah efektif atau belum. Tujuan penelitian ini untuk mengetahui penggunaan aplikasi mobile JKN dan bagaimana efektivitas penggunaan aplikasi tersebut di Kantor Cabang. Metode analisis yang digunakan adalah analisis deskriptif. Hasil penelitian menunjukkan faktor-faktor yang menyebabkan rendahnya penggunaan aplikasi mobile JKN yaitu disebabkan oleh peserta yang enggan menggunakan aplikasi tersebut, peserta lebih memilih datang langsung ke Kantor Layanan, peserta berasal dari daerah sulit, kurangnya pengetahuan masyarakat tentang perkembangan teknologi yang dapat di gunakan dengan satu genggaman yakni gawai
Pengaruh Kinerja Perusahaan pada Pelaporan Corporate Social Responsibility yang Dimoderasi Siklus Hidup Perusahaan di Indonesia
Authors: Andari Caecilia Rina , Desiyanti Desiyanti , Lestari Henny Setyo , Leon Farah Margaretha
Published: March 2022

Saat ini dorongan untuk mengungkap seluruh aktivitas CSR perusahaan sebagai wujud tanggung jawab sosial perusahaan sangat besar. Namun implementasi CSR masih membutuhkan perhatian dari banyak pihak, secara khusus di Indonesia pelaksanaannya masih mengalami hambatan karena orientasinya masih kepada keuntungan komersial perusahaan. Penelitian ini bertujuan untuk melihat seberapa besar pengaruh kinerja perusahaan pada pelaporan Corporate Social Responsibility (CSR) serta bagaimana siklus hidup perusahaan dapat memoderasi hubungan kinerja perusahaan dan pelaporan CSR. Penelitian ini menggunakan variabel independen kinerja perusahaan dengan variabel dependen pelaporan CSR serta variabel moderasi tahapan siklus hidup perusahaan. Berbeda dari penelitian sebelumnya, pada penelitian ini ditambahkan Return on Equity (ROE) ke dalam variabel independen. Penelitian ini menggunakan sampel data dari 23 perusahaan pada industri consumer goods yang terdaftar di Bursa Efek Indonesia selama kurun waktu 5 tahun (2016-2020). Metodologi dasar yang digunakan dalam penelitian ini adalah model regresi Fixed Effect Model yang dilengkapi dengan statistik deskriptif dan diolah dengan menggunakan Eviews 10. Hasil penelitian menunjukkan bahwa kinerja perusahaan dari pengukuran variabel ROA dan ROE memiliki pengaruh signifikan terhadap pelaporan CSR. Tahapan siklus hidup perusahaan juga memberi pengaruh signifikan pada pelaporan CSR. Demikian halnya dengan seluruh variabel kinerja perusahaan yang dimoderasi dengan siklus hidup berpengaruh signifikan kepada pelaporan CSR.
Penyakit Akibat Makanan Sebelum dan Sesudah Intervensi Higiene Sanitasi Makanan di Kantin PT. X, Industri Kertas di Sumatera Selatan, Indonesia
Authors: Adiwinata Freddy , Maverick Bertrand
Published: March 2022

Penelitian ini bertujuan menyelidiki kebermaknaan hubungan antara angka kejadian penyakit akibat makanan sebelum dan sesudah intervensi higiene sanitasi makanan di kantin perusahaan. Setelah 2 kejadian luar biasa penyakit akibat makanan, manajemen perusahaan melakukan beberapa intervensi higiene sanitasi makanan utnuk memperbaiki kondisi kantin sejak Oktober 2019 sampai dengan Desember 2019. Peneliti membandingkan semua diagnosis penyakit akibat makanan dari rekam medis klinik perusahaan yaitu dari September 2018 sampai September 2019 (sebelum intervensi) dan dari Januari 2020 sampai September 2020 (sesudah intervensi). Dengan paired T-test dan Wilcoxon Signed-Rank Test, taraf signifikansi < 0.05, peneliti mendapatkan p-value sebesar 0.03125, artinya intervensi higiene dan sanitasi makanan dapat secara bermakna menurunkan angka kejadian penyakit akibat makanan.
Sistem Pendukung Kepustusan Pemilihan Tempat Kos Untuk Mahasiswa di Gresik dengan Metode SAW (Simple Additive Weighting)
Authors: Akbar Soffan Maulana , Anugrah Indra Gita
Published: March 2022

Indekos atau biasa disebut kos merupakan salah satu tempat penyedia jasa penginapan atau tempat tinggal sementara yang terdiri dari beberapa kamar dimana setiap kamar memiliki fasilitas yang telah disediakan oleh pemilik kost. Bagi mahasiswa yang berkuliah jauh dari daerah asal tentunya membutuhkan kost. Pada proses pemilihan kost mahasiswa yang berkuliah di Gresik sering kali mengalami kesulitan dan kendala dalam pemilihan kost tersebut dikarenakan ada beberapa kriteria dan faktor-faktor yang harus dipenuhi seperti lokasi, harga, fasilitas, dan juga keamanan. Untuk mengatasi permasalahan diatas diperlukan sebuah sistem untuk membantu mahasiswa di Gresik sebagai rekomendasi dan juga mencari informasi tentang kost yang ada di Gresik. Makadari itu dipilihlah suatu metode dari beberapa metode yang ada yakni metode Simple Additive Weighting (SAW). Metode ini nantinya akan menghasilkan nilai terbesar yang akan terpilih sebagai alternatif terbaik dengan memperhitungkan kriteria yang ada
Restoring a Willingness to Act: Identifying and Remedying the Harm to Authorized Employees Ignored Under Hoffman Plastics
Authors: Trivedi Rita
Published: March 2022

Part I of this Article provides a background for both the NLRA and the IRCA. It examines the goals and remedies of both statutes as well as the impact of the Supreme Court’s Hoffman decision on available remedies.

Part II addresses the currently-skewed remedial incentives. It considers why employers are tempted to hire unauthorized workers and commit unfair labor practices that are then inadequately remedied, which creates a situation that adversely effects the rights of authorized employees.

Part III more closely analyzes this consequential harm. This Part identifies the erosions on the NLRA’s collective nature and the impact on authorized employees’ terms and conditions of employment as well as their ability to change them. It also examines the far-reaching erosion of mental confidence experienced by authorized employees when considering their statutorily protected rights. This chilling effect, when unaddressed, represents a failure of the NLRA to achieve its remedial goal to restore the status quo ex ante to the employer’s unfair labor practice.

In Part IV, this Article considers the literature addressing remedies in cases involving unauthorized workers, including the many existing suggestions for refinements that might bring balance to the currently misaligned incentive structure. It observes, however, that these proposals reflect a current focus on unauthorized workers that not only poses practical and political dilemmas if implemented but, as a normative measure, continues to overlook the problem of the harm done to authorized employees—and may even cause them further harm.

Given that any attempt to amend the NLRA or modify Hoffman to account for this developing problem is almost certainly doomed to fail in the foreseeable future, Part V concludes that it may be more expedient to work within the existing statutory text and case law to address the distinct harm to authorized worker as a part of the restoration of the status quo. It therefore suggests that in cases where an unfair labor practice has been found involving an unauthorized worker, the General Counsel and the Board should routinely consider expanded appropriate remedies. These remedies could potentially include longer notice posting times, notice mailing with explanatory material educating the remaining workers of their rights, publication of the notice for a period of weeks in a publication of general circulation, visitation to ensure compliance with the Board’s order, and other measures designed to restore the confidence and willingness to act of employees, particularly the authorized workers who have been harmed by their employer’s actions.
Promoting Environmental Education in Moroccan High School ELT Textbooks
Authors: Laaloua Hassan , Tamer Youssef
Published: March 2022

This paper examines the extent to which three Moroccan high school ELT textbooks integrate environmental education contents. The analysis focuses on four environmental education topics namely ecosystems and cycles, pollution, use of resources, and environment preservation as well as their subtopics. The study is informed by the theoretical framework developed by the BIOHEAD-CITIZEN project that aimed at understanding how environmental education can promote citizenship. This study adopted a convergent parallel mixed method design using content analysis to investigate the degree of presence of environmental education elements in Visa to the World, Ticket to English, and Ticket 2 English. The results revealed statistical evidences indicating that environmental education integration in these textbooks appeals to the learners’ minimum fundamental environmental knowledge, awareness, attitudes and behaviors. Ultimately, this study suggests ways in which textbooks could contribute to improve students ‘environmental knowledge, attitudes, and behavior.
TELAAH MINIMNYA APRESIASI PADA KARYA SENI GRAFIS DI SUMATERA KHUSUSNYA DI KOTA PALEMBANG
Authors: Iswandi Heri
Published: March 2022

              Sebagai kata benda abstrak ‘seni’ adalah kemampuan kreatif manusia dalam menanggapi alam; kemampuan istimewa dalam mangubah suatu ide menjadi konsep kreatif yang dinyatakan menjadi suatu yang menarik, fungsional atau inspiratif. Seni adalah hasil karya manusia yang dibuat melalui proses pengerjaan yang memerlukan ketrampilan khusus atau luar-biasa. Dalam berkarya seni, kepentingan pribadi bagi si senimannya tentunya berbeda-beda, ini disebabkan oleh kebutuhan hidup dan pemaknaan hidup yang bebeda-beda pula. Kepentingan pribadi yang bebeda-beda semacam itu mengakibatkan penikmat seni juga mencari sendiri nilai-nilai pribadinya pada sebuah karya seni, dan hal tersebutlah yang membuat seseorang memiliki apresiasi seni yang berbeda-beda. Salah satu cabang seni murni, yaitu seni grafis dalam kaitannya dengan media ataupun teknik yang dipakai dalam pengungkapan kreatifitas seni grafis seharusnya tidak perlu diperdebatkan, yang utama adalah seni grafis yang me-Indonesia, yang menunjukkan identitas grafis yang dimiliki Indonesia tanpa terpengaruh oleh negara lain. Karya seni grafis selalu lekat dengan teknik dan medium yang digunakan. Sejak seni grafis berkembang di Indonesia, perkembangannya seakan semakin merosot tajam. Seni grafis menjadi cabang seni murni yang konvensional dengan teknik dan mediumnya. Namun lama-kelamaan pemikiran itu mulai hilang dengan adanya karya-karya seni grafis baru yang merespon kekayaan teknik dan medium. disertai oleh pemikiran konsep yang plural. Di dalam penelitian ini, penulis mencoba untuk menelusuri fungsi seni grafis di tengah masyarakat, Khususnya di kota Palembang. Seni grafis sebagai salah satu medium seni rupa memang belum sepopuler seni lukis, patung, dan bahasa rupa lainnya. Seni grafis baru terindentifikasi ketika bersinggungan dengan ranah pendidikan. Padahal seni grafis sudah dikenal di Indonesia sejak 1940-an. Banyak hal yang membuat seni grafis sebagai bahasa rupa kurang memasyarakat. Namun, bukan berarti seni grafis tidak mempunyai nilai lebih dari genre seni rupa lainnya.
PERANCANGAN KAMPANYE SOSIAL BAHAYA PENGGUNAAN POLISTIRENA BUSA SEBAGAI KEMASAN MAKANAN DAN MINUMAN PADA KALANGAN PEDAGANG DI KOTA PALEMBANG
Authors: Riansyah Raden Okta , Mubarat Husni , Yulius Yosef
Published: March 2022

Penggunaan kemasan polistirena busa yang berkali kali pada jenis sekali pakai dapat menyebabkan penyakit terhadap kesehatan manusia mulai dari menganggu sistem syaraf,  alergi kulit, sulit tidur, iritasi mata, diare bahkan dapat memicu kanker. Untuk di Kota Palembang, sampai saat ini masih banyak pedagang makanan yang menggunakan polistirena busa sebagai kemasan makanan, seperti pedagang bubur ayam, seblak, dan nasi goreng, tanpa menyadari bahaya yang ditimbulkan. Oleh karena itu perlu adanya perancangan kampanye sosial mengenai dampak penggunaan polistirena busa yang berlebihan.  Adapun metode pengumpulan data pada perancangan karya ini dititikberatkan pada identifikasi data, analisadata  dan perancangan pada karya Ambient media tempat sampah dan media pendukung lainnya. Perancangan ini menggunakan metode perencanaan design thinking meliputi premedia, main media dan follow up media. Data dikumpulkan melalui, observasi, wawancara, literatur dan website. Data tersebut kemudian diidentifikasi, diklasifikasi, diseleksi, selanjutnya dianalisis menggunakan metode 5W+1H, dan diinterpretasikan sesuai teks dan konteksnya. Perancangan ini bertujuan mengajak masyarakat Kota Palembang khususnya para pedagang untuk beralih ke kemasan yang lebih Higenis. Adapun karya yang dibuat pada perancangan ini diantaranya adalah ambient media berupa tempat sampah, poster, apron, T-Shirt, Masker, dan X Banner.
Hubungan Produktivitas dengan Tingkat Kesejahteraan Petani Jambu Mete di Desa Pebaoa Kecamatan Kulisusu Utara Kabupaten Buton Utara
Authors: Wati Herlina , Hidrawati Hidrawati , Limi Muhammad Aswar
Published: March 2022

A study to determine the relationship between productivity and welfare level of cashew farmers. The welfare group consists of several indicators: income, house construction, and children's education level. This research was conducted ini Pebaoa Village, North Kulisusu District, Nort Buton Regency, from August to September 2021. The data analysis used in this study is a quantitative descriptive analysis technique using the Chi-Square test formula (X2). The population of this study amounted to 182 farmers. Sampling was done at a simple random sampling by taking an error rate of 15% and obtaining a sample of 35 farmers. Primary data and secondary data are the two forms of data. Preliminary data was gathered by direct observation and questionnaire interviews with respondents, while secondary data was collected through entities involved in the study. The findings revealed a link between productivity and farmer well-being markers, such as income, housing style, and children's education level. The X2 value obtained from each welfare indicator is 5,07; 4,5 and 4,94, which are more significant than the table X2 value at the 95% confidence level.
El reverso que no vemos. Hallazgo de un conjunto gótico actualmente disperso a partir del estudio del soporte.
Authors: Bautista Morenilla Iris , Nualart Torroja Anna , Oriola-Folch Marta
Published: March 2022

Este estudio confirma que el frontal de santa Eugenia (MAD 121, París) y los laterales de Ribes (MEV, 9494/9495) formaban un conjunto que originalmente guarnecía el altar principal de la iglesia románica de santa Eugenia de Saga (Cerdaña, Cataluña). Al conjunto se le perdió el rastro tras la venta del frontal a un anticuario francés en 1896. Frontal y laterales no se habían vuelto a poner en relación debido a las diferencias de la policromía y a su supuesta procedencia distinta hasta la realización de esta investigación.

Las evidencias han sido halladas mediante el análisis científico del soporte y el estudio de los vestigios de policromía conservados en los marcos de las tres obras. Esta es la segunda vez que se ha demostrado la unidad de un conjunto de altar del período del gótico lineal a partir del estudio del soporte, hecho que pone de relieve la importancia de los estudios técnicos de conservación-restauración.
Evidence of attentional bias toward body stimuli in men
Authors: Talbot Daniel , Saleme Daniella
Published: March 2022

Over the past 30 years, attentional bias for body shape and weight content has been implicated in the precipitation and maintenance of body dissatisfaction and eating disorders. Although the existence of this bias toward body stimuli is well-established in female populations, it is comparatively understudied in men. This review aimed to examine the nature of this visual attentional bias toward male bodies in male samples across a range of different attentional paradigms, including eye-tracking, dot-probe, and the visual search task. Results were heterogenous, finding some evidence that men with higher body dissatisfaction and eating disorder symptoms demonstrated an attentional bias toward desirable bodies of other men, and undesirable features of their own bodies. These results suggest that schematic cognitive models of body dissatisfaction and eating disorders body may also be applicable to men, however more research is needed.
Approaching microwave photon sensitivity with Al Josephson junction
Authors: Pankratov Andrey L , Gordeeva Anna V , Revin Leonid S , Ladeynov Dmitry A , Yablokov Anton A , Kuzmin Leonid S
Published: March 2022

Here we experimentally test the applicability of aluminum Josephson junction of few microns size as a single photon counter in microwave frequency range. We have measured the switching from the superconducting to the resistive state due to absorption of 10 GHz signal. The dependence of the switching probability on the signal power suggests that the switching is initiated by simultaneous absorption of three and more photons with the dark count time above 0.01 s.
El cambio global y la educación superior
Authors: Martel-Carranza Christian , Torero Solano de Martel Nathalie Zinzia
Published: March 2022

La presente editorial tiene como finalidad indagar el rol de la universidad en el cambio global, teniendo en consideración los retos que nos trae la COVID-19 y los nuevos panoramas sociales. La universidad en el Perú y en el mundo detenta grandes responsabilidades como generadora del cambio social; lo que se tratará de explicar en las siguientes líneas. La educación, en todos sus niveles, es considerada como un factor clave para la generación de mayores ingresos salariales, movilidad y bienestar social
Tidally Tilted Pulsations in HD 265435, a Subdwarf B Star with a Close White Dwarf Companion
Authors: Jayaraman Rahul , Handler Gerald , Rappaport Saul A. , Fuller Jim , Kurtz Donald W. , Charpinet Stéphane , Ricker George R.
Published: March 2022

Tidally tilted pulsators (TTPs) are an intriguing new class of oscillating stars in binary systems; in such stars, the pulsation axis coincides with the line of apsides, or tidal axis, of the binary. All three TTPs discovered so far have been δ Scuti stars. In this Letter, we report the first conclusive discovery of tidally tilted pulsations in a subdwarf B (sdB) star. HD 265435 is an sdB–white dwarf binary with a 1.65 hr period that has been identified and characterized as the nearest potential Type Ia supernova progenitor. Using TESS 20 s cadence data from Sectors 44 and 45, we show that the pulsation axis of the sdB star has been tidally tilted into the orbital plane and aligned with the tidal axis of the binary. We identify 31 independent pulsation frequencies, 27 of which have between 1 and 7 sidebands separated by the orbital frequency (ν
orb) or multiples thereof. Using the observed amplitude and phase variability due to tidal tilting, we assign ℓ and m values to most of the observed oscillation modes and use these mode identifications to generate preliminary asteroseismic constraints. Our work significantly expands our understanding of TTPs, as we now know that (i) they can be found in stars other than δ Scuti pulsators, especially highly evolved stars that have lost their H-rich envelopes, and (ii) tidally tilted pulsations can be used to probe the interiors of stars in very tight binaries.
The Most Common Cardiovascular, Orthopedic, and Neurological Problems in the Elderly and Nursing Care
Authors: Pirushi Rudina , Imeraj Zamira , Veseli Denisa , Bilali Valbona
Published: March 2022

AIM: Health problems of the elderly in addition to purely medical constitute a complex and quite acute social, economic, psychological, and spiritual problem, which are growing unstoppably everywhere in the world. The main purpose of this study is to assess the general health of the elderly, to identify the most common pathologies, and to describe the role and responsibilities of the nurse in the elderly with cardiovascular, neurological, and orthopedic diseases, in all patients in geriatric clinics.

METHODS: The method used during this study was conducted through a questionnaire of the elderly in geriatric centers. The paper includes data on patients during the period April–June, 2020.

RESULTS: Data were observed on 300 elderly persons of whom 100 persons or 33% were female and 200 persons or 67% were male. The mean age of patients was 90 ± 65 years. These elderly people were given information about living conditions, social problems, diseases they had, etc. The most common pathologies of these elderly people studied were cardiovascular problems 25%, orthopedic problems 31%, and neurological problems 43%. We see that women are more predisposed to cardiovascular problems in 66% of cases compared to men in 34% of cases; most predisposed to orthopedic problems are again women in 55% of cases compared to men in 45% of cases and more predisposed to neurological problems are men in 60% of cases and women in 40% of cases, it is significant (p < 0.001).

CONCLUSIONS: From the above data, it is noticed that almost all the elderly have a concomitant disease. The role of the nurse should be to focus on the daily monitoring of the patient’s condition, to identify in time the possible risks, and to explain to the patient how to take the therapy, how long to take this therapy, what may be the side effects and how medications should be combined.
Pre-dialytic Systolic Blood Pressure is an Independent Predictor of Intradialytic Hypertension
Authors: Rifai Achmad , Soelistyoningsih Dwi , Fajar Jonny Karunia , Gunawan Atma
Published: March 2022

BACKGROUND: Since endothelial dysfunction and activation of renin-angiotensin aldosterone system are the primary mechanism of intradialytic hypertension (IDHT), the assessment of pre dialytic blood pressure might provide an important information for the prediction of IDHT.
OBJECTIVES: To assess the association between pre dialytic blood pressure and the risk of IDHT.
METHODS: We conducted a cross-sectional study in Universitas Muhammadiyah Malang Hospital. The inclusion criteria were all hemodialysis patients aged more than 18 years, and the exclusion criteria were patients with hemodialysis duration of less than three months, patients with poor compliance to consume antihypertensive drugs, and hemodynamically unstable. The predictor variable was pre dialytic systolic blood pressure and the outcome was the incidence of IDHT. The association between pre dialytic blood pressure and the risk of IDHT was assessed using multiple logistic regression.
RESULTS: A total of 36 patients with IDHT and 60 patients without IDHT was enrolled in our study. Our study identified that pre dialytic systolic blood pressure was associated with the risk of IDHT, with mean difference was 10.90 mmHg between patients with IDHT and without IDHT. Our study confirmed that the levels of pre dialytic systolic blood pressure 135 mmHg was the optimal cut off, and we found that patients with pre dialytic systolic blood pressure ≥ 135 mmHg had 4.60-fold to develop IDHT compared to patients with pre dialytic systolic blood pressure < 135 mmHg.
CONCLUSION: Our study reveals that pre dialytic systolic blood pressure is an important predictor of IDHT.
The Effect of Topical Ozonated Aloe vera on VEGF Expression and Microvascular Density in Radiation Dermatitis
Authors: Prajoko Yan Wisnu , Silalahi Davin Rizky Parulian , Priharsanti Christina Hari Nawangsih , Supit Tommy
Published: March 2022

BACKGROUND: Radiation dermatitis is one of the most common side effects of external radiation therapy. Ozonated Aloe vera oil is a novel topical intervention with immunomodulatory properties that have been proven to improve wound healing by promoting fibroblast proliferation and collagen synthesis.

AIM: The purpose of this study was to investigate the effect of topical ozonated A. vera oil application on the vascularization aspect of wound healing in a radiation dermatitis animal model.

METHODS: Thirty-six adult male Sprague Dawley rats were randomized into six groups of equal size (n = 6/group): two control and four intervention groups: Positive control (C1) rats were not given any therapy, and comparative control (C2) rats were given topical hydrocortisone cream 2.5%. Subjects in the P1 group were given non-ozonated A. vera therapy, P2 group was given 300 mg/mL ozonated A. vera, P3 group was given 600 mg/mL ozonated A. vera, and P4 was given 1200 mg/mL ozonated A. vera therapy. Subject termination and histopathological analyses of vascular endothelial growth factor (VEGF) and microvascular density were carried out after 7 treatment days.

RESULTS: Based on Weidner microvascular density scoring system, the least microvascular density was observed in C2, P3, and P4 (2.0 ± 0.0), followed by P1 (2.1 ± 0.1), P2 (2.9 ± 1.5), and C1 (3.0 ± 0.7). Based on immunoreactive immunoreactive score (IRS) VEGF scoring system, the lowest expression of VEGF was observed in group P3 (4.1 ± 1.1), followed by P4 (4.3 ± 0.8), C2 (4.3 ± 1.3), P1 (5.1 ± 1.0), P2 (5.4 ± 0.6), and C1 (6.5 ±1.0). There was a strong positive correlation of VEGF and microvascular density.

CONCLUSION: Topical application of ozonated A. vera to the radiated skin of Sprague Dawley rats reduced VEGF expression and microvascular density. This anti-inflammatory effect may suggest its potential clinical application.
Comparison of V Technique and Femoral Arterial Palpation Techniques Accuracy in Identifying the Femoral Vein’s Cannulation Site
Authors: Tantri Aida Rosita , Alatas Anas , Dharma Reza Surya
Published: March 2022

BACKGROUND: The femoral vein cannulation is essential for vascular access and finding it by just relying on the femoral artery pulsation can be challenging in a certain condition. V technique is a new technique to identify the femoral vein’s cannulation site based on topographic anatomy without relying on femoral artery pulsation.

AIM: This study was aimed to compare V technique and arterial palpation technique accuracies in identifying the femoral vein’s cannulation site.

METHODS: This study was a cross-sectional study on 115 adult patients aged 18–65 years old with body mass index 18–25 kg/m2 who underwent elective surgery in Cipto Mangunkusumo National General Hospital on February-March 2020. After ethical approval and informed consent, the distance of the femoral vein’s cannulation site identified by both techniques with the skin projection of the femoral vein diameter identified by ultrasonography (USG) were compared in all subjects. Accuracy was defined when the femoral vein’s cannulation sites identified by both techniques were within the skin projection of femoral vein diameter identified by USG. Data were collected and analyzed using SPSS ver 20.

RESULTS: The accuracy of the V technique in determining the femoral vein’s cannulation site was 93.9%, while the accuration of the femoral artery pulsation technique was 96.5%. Mcnemar analysis showed no difference in both techniques’ accuracy (p = 0.549). There was a statistically significant positive correlation between the distance of the femoral vein cannulation site predicted by both techniques with the skin projection of the femoral vein midpoint (r = 0.548; p < 0.001).

CONCLUSION: V technique’s accuracy was not significantly different from the femoral artery pulsation palpation technique’s accuracy in identifying the femoral vein cannulation site.
The Association between Mean Arterial Pressure, Central Venous Pressure, Cerebral Perfusion Pressure, Lung Oxygenation, and Glasgow Coma Scale in Sepsis Patients in the Intensive Care Unit
Authors: Lubis Bastian , Amelia Putri , Akil Muhammad , Viandy Vincent
Published: March 2022

BACKGROUND: Sepsis is the most frequent condition encountered in the intensive care unit (ICU). One of the neurological features of sepsis is sepsis-associated encephalopathy (SAE). The exact pathophysiology of SAE remains unclear. Many factors have been linked to SAE, such as hypotension, hypoxemia, and other metabolic abnormalities. However, alteration of cerebral blood flow is thought to be the main culprit behind SAE.

AIM: This study aims to evaluate and find correlations between mean arterial pressure (MAP), central venous pressure (CVP), cerebral perfusion pressure (CPP), PaO2/FiO2 (PF) ratio, Glasgow Coma Scale (GCS), and level of consciousness.

METHODS: A cross-sectional study was conducted from March 2020 to October 2020 in the ICU of H. Adam Malik Central Hospital, Medan, Indonesia. Patients over 18 years old with sepsis were included in this study. We recorded the demographic data, MAP, CVP, CPP, PF ratio, and GCS in the 1st h of ICU admission. The data were then analyzed to find the correlation between these parameters.

RESULTS: The total subjects in this study were 62 patients, with an equal ratio of male-to-female. A quarter of the patients were intubated, affecting the GCS assessment. The median of GCS was 12. Most patients (46.8%) were determined to be somnolence. The mean age of the subjects is 54.84 ± 13.25 years old. There was no correlation between MAP, CVP, CPP, PF ratio, GCS, and level of consciousness in this study.

CONCLUSIONS: Our study found no correlation between MAP, CVP, CPP, PF ratio, GCS, and level of consciousness in sepsis patients.
Enhancement of onion bulb drying with air dehumidification assisted dryer
Authors: A'yuni Dewi Q. , Djaeni Mohamad , Asiah Nurul , Subagio Agus
Published: March 2022

Drying is an important process in onion bulb processing to preserve product quality and storage time. This paper discusses how to find an onion bulb with acceptable moisture content and high ingredient retention rate with minimized heat usage. As indicators, moisture content, riboflavin (Vitamin B2) content, and heat efficiency are evaluated at different drying temperatures and air relative humidity. In doing so, the response surface method is employed to find the most favorable drying condition. Polynomial regression was found to be a good fit in predicting moisture content, while heat efficiency response is significantly fit after dehumidification is applied. Moreover, onion drying with air dehumidification has more advantages than that of without dehumidification. With low air relative and medium drying temperature, the heat efficiency of the onion bulb drying can be positively improved with an acceptable riboflavin retention. Analysis of variance revealed that air dehumidification and drying temperature have a significant impact on the drying time and heat efficiency. However, at high air temperatures, the effect of air dehumidification is limited.
AVALIAÇÃO E PROCESSOS DE SUBJETIVAÇÃO NA ATENÇÃO BÁSICA À SAÚDE: AVALIAÇÃO E SUBJETIVAÇÃO
Authors: Ferreira Neto João Leite , Duarte Luiz Guilherme Mafle Ferreira , Penido Cláudia Maria Filgueiras
Published: March 2022

Desde a redemocratização no Brasil, o tema da subjetividade tem sido um componente importante na discussão e na formulação das políticas públicas no país. Existe um grande embate na literatura em torno dos méritos e dos prejuízos decorrentes dos processos de avaliação. O objetivo desta pesquisa é investigar os efeitos das práticas avaliativas nos processos de subjetivação vividos por profissionais das equipes de Saúde da Família na Atenção Básica, em um distrito sanitário do município de Belo Horizonte. Buscamos também compreender os efeitos da avaliação na subjetividade dos profissionais envolvidos. Realizamos 16 entrevistas semiestruturadas com os profissionais e gestores de duas Unidades Básicas de Saúde. Fizemos uma análise temática das entrevistas em três eixos: os ganhos desencadeados pelas práticas de avaliação, os seus aspectos problemáticos e os processos de subjetivação decorrentes das avaliações. Os ganhos que as avaliações permitiram foram: detectar as falhas no trabalho e redirecionar as atividades; melhorar o atendimento à população e modificar o comportamento com os colegas e em relação ao trabalho. As críticas se direcionaram aos indicadores dos instrumentos, aos processos de avaliação, à dificuldade de colocar em prática os resultados obtidos e ao não cumprimento dos acordos por parte dos gestores municipais. Os processos de subjetivação promovidos pelas avaliações foram por um lado a reflexão em relação ao trabalho e aos colegas, produzindo mudanças de atitudes, e por outro os sentimentos de medo, culpa e frustração em relação ao processo de avaliação, seus resultados e consequências.
A DROGA COMO DISPOSITIVO DE CONTROLE SOCIAL: UMA ANÁLISE DAS REPRESENTAÇÕES SOCIAIS DO ÁLCOOL, MACONHA E CRACK NA IMPRENSA BRASILEIRA
Authors: Acioli Neto Manoel de Lima , Santos Maria de Fátima Sousa , Sobral Mariana Oliveira , Pessoa Mariana
Published: March 2022

As drogas se consolidam como um dos arquétipos culturais predominantes no cotidiano das sociedades urbanas, sendo sua presença ubíqua em praticamente todas as culturas. Os registros históricos apresentam ampla variabilidade de substâncias que em dado momento eram classificadas como o perigo social da época e que em outro se tornavam banalizadas ou tipificadas como inofensivas. Assim, esse estudo teve como objetivo analisar como dispositivo droga que se consolida em diferentes períodos históricos. Para isso, foram coletadas 4.227 matérias dos jornais Folha da Manhã, Folha da Noite e Folha de São Paulo, que abordassem questões relativas ao álcool (década de 1920), maconha (décadas de 1930 a 1960) e crack (década de 1980 a 2005) e realizada Análise Temática de Conteúdo. Os resultados permitem afirmar que a característica central que define todas as substâncias analisadas nos distintos momentos históricos é o risco social que ela apresenta. A droga se constitui como um risco aos usuários ao mesmo tempo que os institui enquanto uma figura de ameaça social. Ao se referenciar uma substância como uma droga, são ativados sentidos que remetem a um quadro de decadência e criminalidade.
Integrating user Psychology in Road Transport Safety: A Model for Low and Middle-Income Countries, Based on Sri Lanka
Authors: Kandanaarachchi T. , Sugathadasa P. T. R. S. , Perera H. N.
Published: March 2022

Low and Middle Income Countries (LMICs) account for 90% of road collisions that occur globally. These collisions account for 17.63 million serious injuries and deaths while costing LMIC economies 1.7 trillion USD amounting to 6.5% of aggregate annual GDP. Though there are a plethora of models on road transport safety, few address the impact of user psychology and the contextual environment in LMICs on road safety. This paper proposes such a model formulated and developed using existing literature and focus group discussions. The model is composed of three key constituents - behaviour, skills and knowledge, and infrastructure. It further interprets behaviour as an integration of three sub-elements—mindset, circumstances and legal system—pertaining to the incident. The interaction between these constructs constitutes user behaviour in a given circumstance. The research also proposes an implementation guideline to authorities that is instrumental in changing society’s perception of transport safety.
A Study on Chemotherapy of Pulmonary Tuberculosis
Authors: Kim Kyung Sik
Published: March 2022

The effects of various chemotherapy on about 100 cases of pulmonary tuberculosis were compared, and the following results were obtained.1. When the antituberculous agent is used in large dosage at the beginning of therapy, the bacteriological effect is more prominent.2. Regimen of combination of four antituberculous drugs showed no better results than the triple therapy.3. In cases with hard-to-heal tuberculous lesions, on whom antituberculous drugs had been used in sufficient amounts the use of large dosage of INH in SM + PAS + INH regimen, INH + CS regimen, or INH + CS + PAS regimen (CS = Cycloserine)was most effective.4. In case of repeated hemoptysis during the use of INH, replacement with Reazide is effec tlve.5. Among seven cases of open healing of cavities, four has been engaged in works for more than a year without recurrence.6. Rest during chemotherapy is more necessary when the tubercle bacilli are drug resistant.
An Analysis of the Causes of Failure in the Treatment of Pulmonary Tuberculosis and Results of Subsequent Treatment
Authors: Lee Hyo Keun , Ham Sung Suk , Park Sung Ok , Choi Yong Ok , Min Bum Shik
Published: March 2022

The purpose of this study is to analyze the causes of treatment failure in pulmonary tuberculosis and the results of subsequent treatment. Patients whose sputum remained positive for acid-fast bacilli after one year's chemotherapy were classed as “ treatment failures". A hundred and fity-eight treatment failures were reviewed and following results were found. The main causes of treatment failure were (1) treatment began late in the cause of the disease and (2) irregular chemotherapy. These were due to the fact that pulmonary tuberculosis usally fails to produce any symptom which can be recognized by the patient and the tendency of patient to judge the condition of his lungs according to symptoms.The results of subsequent treatment with various anti-tuberculosis agents of treatment failure cases were very slight and there was no significant difference among the various regimens employed. Combination of various drugs showed no significant superiority over that obtained by INH alone. INH is much cheaper and so adequate for this type of patient.
Surgical Consideration for Bronchial Tuberculosis seen on the Resected Specimens
Authors: Lee Hong K.
Published: March 2022

In considering the surgical resections treatment for the pul. tbc., the very existence of the bronchial tbc. is Iiable to cause various post-operative complications such as broncho-pleural fistulas and spreadings of Iesions to healthy pulmonary resions. We have seen on the microscopic examination of the 115 resected Lnng specimens, 16 cases.(13.9%), who had preoperative combined therapy extending from 0 to 20 months duration, with tuberculous lesions on their bronchial walls. Of these 16 cases, 8 from cases of lobectomy and 8 from cases of segmental resections sere derived respectively, 15 were navy personnel and 1 was a civilian. Original lesions of these 16 cases were 13 cavitations, 1 tuberculoma, 2 small foci and the microbiological study on these showed 13 cases to be positive both on staining and cultures, 1 case to be negative on the staining while positive on the culture and 2 cases to be positive on the stainings while negative on the cultures. As for the sites of the lesions of these 16 cases of bronchial tuberculosis, 6 lesions seen on the mucosal layer, 6 in the submucosal, 5 in the muscular, 5 don't the serosal, 4 on the glands, and 1 invaded cartilage were noticed respectively. And describing the findings of lesions, 3were tubercles with liquefactions, 1 was tubercle with central calcification, 2 with squamous metaplasia of the mucosal epithelium and the rest of lesions showed solid tubercles only. The 5 cases with 7 complications out of these 16 cases were observed that is, 2 cases with blood in sputa, 3 with bronchopleural fistulated and 2 with lesions spread to the healthy regions. Of these last 2 one died accompanying bronchopleural fistule and pyothorax and the other is still receiving medical treatment for three years after the operation, although, except these 2 cases the rest showed drastic cures with massive antibiotic treatment provided.
IL-27 Enhances γδ T Cell–Mediated Innate Resistance to Primary Hookworm Infection in the Lungs
Authors: Sharma Arjun , Noon Jason B , Kontodimas Konstantinos , Garo Lucien P , Platten Johannes , Quinton Lee J , Urban Joseph F , Reinhardt Christoph , Bosmann Markus
Published: March 2022

IL-27 is a heterodimeric IL-12 family cytokine formed by noncovalent association of the promiscuous EBI3 subunit and selective p28 subunit. IL-27 is produced by mononuclear phagocytes and unfolds pleiotropic immune-modulatory functions through ligation to IL-27 receptor α (IL-27RA). Although IL-27 is known to contribute to immunity and to limit inflammation after various infections, its relevance for host defense against multicellular parasites is still poorly defined. Here, we investigated the role of IL-27 during infection with the soil-transmitted hookworm, Nippostrongylus brasiliensis, in its early host intrapulmonary life cycle. IL-27(p28) was detectable in bronchoalveolar lavage fluid of C57BL/6J wild-type mice on day 1 after s.c. inoculation. IL-27RA expression was most abundant on lung-invading γδ T cells. Il27ra−/− mice showed increased lung parasite burden together with aggravated pulmonary hemorrhage and higher alveolar total protein leakage as a surrogate for epithelial–vascular barrier disruption. Conversely, injections of recombinant mouse (rm)IL-27 into wild-type mice reduced lung injury and parasite burden. In multiplex screens, higher airway accumulations of IL-6, TNF-α, and MCP-3 (CCL7) were observed in Il27ra−/− mice, whereas rmIL-27 treatment showed a reciprocal effect. Importantly, γδ T cell numbers in airways were enhanced by endogenous or administered IL-27. Further analysis revealed a direct antihelminthic function of IL-27 on γδ T cells as adoptive intratracheal transfer of rmIL-27–treated γδ T cells during primary N. brasiliensis lung infection conferred protection in mice. In summary, this report demonstrates protective functions of IL-27 to control the early lung larval stage of hookworm infection.
Exploration on Nonaxisymmetric Flow Phenomenon in a Slinger Injector
Authors: Wang Fang , Wang Yu-Dong , Gao Xiang , Ye Yu-Long , Liu Rui , Gao Han , Jin Jie
Published: March 2022

The slinger is an important configuration of an aeroengine combustion chamber. It is well matched to smaller gas turbines that are more sensitive to cost than larger and more sophisticated models. The slinger combustor is inherently low cost itself, by eliminating fuel injectors and
much of the fuel tubing and manifolding and also reducing costs in the requirements of the main fuel pump by operating at fuel delta pressures significantly lower than conventional fuel systems. The slinger's inherent drawbacks of increased combustion liner surface area and less atomization
are less of a concern in a lower temperature, lower cost small turbines. The slinger's internal flow is of great significance to fuel atomization. This paper conducts experiments and numerical simulations on the slinger fuel injector. Numerical analysis and high-speed photography of the fuel
slinger were applied to investigate the film flow pattern inside the slinger and the liquid phase distribution inside the combustion chamber to predict the flow field in an aeroengine combustion chamber. The transient Reynolds-averaged Navier–Stokes method, the volume of fluid method,
and the discrete phase method were adopted in the simulation, and a high-speed camera and the rotational rig were used to perform the experiments. The nonaxisymmetric flow was present in the slinger and the combustor space. In the simulation results, the total mass-flow rate varies with time.
Each hole's mass-flow rate value in the slinger is also different at the same time. The Sauter mean diameter (SMD) difference for each injection orifice is relatively small compared with the SMD difference caused by a rotation rate. The spatial distribution of the spray is also uneven as shown
in the result of different single discharge channels' mass-flow rates. The experimental photos confirmed the simulation outcomes. The general theoretical analysis was made that these nonaxisymmetric phenomena were driven by the combined action of centrifugal force, surface tension, and instability
phenomenon.
Therapeutic hypothermia for acute myocardial infarction: a narrative review of evidence from animal and clinical studies
Authors: Jung Ki Tae , Bapat Aneesh , Kim Young-Kug , Hucker William J. , Lee Kichang
Published: March 2022

Myocardial infarction (MI) is the leading cause of death from coronary heart disease and requires immediate reperfusion therapy with thrombolysis, primary percutaneous coronary intervention, or coronary artery bypass grafting. However, myocardial reperfusion therapy is often accompanied by cardiac ischemia/reperfusion (I/R) injury, which leads to myocardial injury with detrimental consequences. The causes of I/R injury are unclear, but are multifactorial, including free radicals, reactive oxygen species, calcium overload, mitochondria dysfunction, inflammation, and neutrophil-mediated vascular injury. Mild hypothermia has been introduced as one of the potential inhibitors of myocardial I/R injury. Although animal studies have demonstrated that mild hypothermia significantly reduces or delays I/R myocardium damage, human trials have not shown clinical benefits in acute MI (AMI). In addition, the practice of hypothermia treatment is increasing in various fields such as surgical anesthesia and intensive care units. Adequate sedation for anesthetic procedures and protection from body shivering has become essential during therapeutic hypothermia. Therefore, anesthesiologists should be aware of the effects of therapeutic hypothermia on the metabolism of anesthetic drugs. In this paper, we review the existing data on the use of therapeutic hypothermia for AMI in animal models and human clinical trials to better understand the discrepancy between perceived benefits in preclinical animal models and the absence thereof in clinical trials thus far.
Treatment of Membranoproliferative Glomerulonephritis with Traditional Chinese Medicine and Rituximab: A Case Report
Authors: Wang Yao-wei , Zeng Qin , Yu Ren-huan
Published: March 2022

Abstract

Membranoproliferative glomerulonephritis (MPGN) is usually characterized by refractory nephrotic syndrome and is associated with a poor prognosis. An older patient diagnosed with MPGN had a 20-year history of proteinuria and had clinical manifestations of nephrotic syndrome in the past 2 years. MPGN. Before the patients received an 11-month traditional Chinese medicine (TCM) treatment, the patient was treated with prednisone, tacrolimus, mycophenolate mofetil, and rituximab for 11 months. After 22 months, the urine protein level decreased to <1 g/d, with normal plasma albumin level, and remarkably increased glomerular filtration rate. Combination of TCM with Western medicine for 22 months was effective for the treatment of MPGN.