bluuebunny/crossref_metadata_2025 huggingface dataset:
PCA morphine for knee ligament reconstruction: age is a factor in consumption
Authors: Laouamri Okba
Published: December 2024

Introduction. The objective of this prospective study was to investigate the
relationship between age and total morphine consumption during knee ligament
reconstruction using three analgesic techniques. Assumption. Young age is a
predictive factor of overconsumption of morphine independently of the intensity of pain.
Materials. 165 patients were Included who underwent primary reconstruction of the
anterior cruciate ligament of the knee. All patients were operated on under spinal
anesthesia. The first systemic analgesia (SA) group will receive systemically balanced
analgesia postoperatively and for a minimum of five days based on Paracetamol,
Diclofenac and a PCA with morphine. The second femoral analgesia (FA) group will
benefit, in addition to the systemic analgesia already described, from a femoral perinervous catheter in the crural position. 20 ml of bupivacaine at 0.125% concentration
is injected; maintenance is implemented immediately with a continuous flow of 8 ml/h
for 36 hours. The third intra-articular analgesia (AIA) group will receive, in addition to
the same systemic analgesia, an infusion through an epidural-type catheter of 20 ml
of 0.125% bupivacaine then maintenance with 8 ml/h of the same local anesthetic by
electric syringe pusher for 36 hours. The cumulative consumption of morphine and the
estimation of pain at rest were evaluated using a numerical scale (EN) from 1 to 10.
Results. Data were collected from H0 to H36. The overall consumption was 15.13 ±
12.35 mg. The difference in consumption was not significant depending on sex and
ASA but it is based on the average age. A negative correlation between age and
morphine consumption exists with a Pearson's R at -0.19 p 0.016. Discussion. this
study raises the suspicion that age is a factor in morphine consumption that must be
taken into consideration when managing postoperative pain, but also when interpreting
research results in this context.
Dermatological features of COVID-19 in pediatric patients. Report of three original cases
Authors: AGGOUNE Samira
Published: December 2024

With the emergence of Covid-19 appeared the description of different skin
manifestations. Although non-specific and rarer than respiratory symptoms, many
case reports were published during 2020, which can be classified into 3 categories.
Histopathological analysis associated with microbiological samples can guide the
diagnosis. Knowledge of these cutaneous manifestations can sometimes help in
diagnosis and allow earlier detection of SARS-CoV-2 infection, especially in patients
with no other systemic symptoms.
Firmaların ekonomik sosyal sorumluluk faaliyetlerinin illerin kalkınmasındaki etkisi
Authors: Bahar Ozan , Nas Yahya
Published: December 2024

Bu çalışmanın amacı, firmaların ekonomik sosyal sorumluluk faaliyetleri ile bulundukları illerin gelişmişlik düzeyi arasındaki ilişkiyi belirlemektir. Bu kapsamda Türkiye İstatistik Kurumu (TÜİK), Sosyal Güvenlik Kurumu (SGK), Türkiye Odalar ve Borsalar Birliği (TOBB), Ticaret Bakanlığı, Sanayi ve Teknoloji Bakanlığı web sitelerinden elde edilen veriler kümeleme analizine tabi tutulmuştur. Dış ticaret hacmi, Ar-Ge merkezi, vergi geliri, işsizlik oranı, imalatçı firma sayısı, ortalama günlük kazanç gibi il bazında firmaların ekonomik faaliyetlerini gösteren 2019-2020 yıllarına ait 19 değişkenin analizinde, hem hiyerarşik hem de hiyerarşik olmayan kümeleme yöntemleri kullanılmıştır. Hiyerarşik kümeleme analizinde iller üç kümeye ayrılırken, hiyerarşik olmayan kümeleme analizinde illerin Kalkınma Bakanlığı tarafından hazırlanan sosyoekonomik gelişmişlik raporu referans alınarak altı küme belirlenmiştir. Her iki analizde de İstanbul tek başına bir küme oluştururken, hiyerarşik kümeleme analizi sonucunda ikinci kümeyi Ankara, İzmir, Bursa, Kocaeli ve Antalya, üçüncü kümeyi ise diğer iller oluşturmaktadır. Hiyerarşik olmayan kümelenme analizinde İstanbul, Ankara ve İzmir illerinin her biri üç ayrı kümeyi oluştururken, Antalya, Bursa ve Kocaeli dördüncü kümeyi oluşturmaktadır. Kalan illerden 15'i bir kümede toplanırken, 60'ı ise başka bir kümede toplandı. Elde edilen sonuçlar, Kalkınma Bakanlığı'nın (2017) hazırladığı illerin sosyoekonomik gelişmişlik endeksi değerleri sıralaması ile büyük ölçüde uyumludur. Firmaların ekonomik sosyal sorumluluk faaliyetlerinin illerin kalkınmasına doğrudan etki ettiği sonucuna ulaşılmıştır.
Sosyal hizmet bölümü lisans öğrencilerinin çevrimiçi yaratıcı drama dersine yönelik tutumları ve ders sürecine ilişkin görüşleri
Authors: Bal İncebacak Belgin
Published: December 2024

Bu araştırma da Sağlık Bilimleri Fakültesi sosyal hizmet bölümü lisans dördüncü sınıf öğrencilerinin aldıkları yaratıcı drama dersine yönelik tutumları ve bu derse yönelik görüşlerinin, yaratıcı drama yöntemi ve mesleki bakış açılarına etkisinin belirlenmesi amacıyla yapılmıştır. Araştırmanın yöntemi Creswell’in karma modelinden sıralı açıklayıcı tasarım desen olarak belirlenmiştir. Çalışma grubunu bir devlet üniversitesi Sosyal hizmetler bölümünde öğrenim gören 56 dördüncü sınıf öğrencileri oluşturmuştur. Veri toplama aracı olarak Adıgüzel (2006a) tarafından geliştirilen “Yaratıcı Drama Dersine Yönelik Tutum Ölçeği” katılımcıların yaratıcı drama dersine yönelik tutumlarını belirlemek için uygulanmıştır. Ayrıca her oturum sonrasında ve dönem sonunda çevrim içi form ile öğrencilerden yaratıcı drama dersine yönelik görüşleri alınmıştır. Uygulama bir dönem boyunca 15 hafta sürmüştür. Haftada 2 saat olacak şekilde toplam 30 saat sürmüştür. Veriler nitel ve nicel olarak toplanmış ve nitel veriler içerik analizi ile nicel veriler ise Mann Whitney U testi ile analiz edilmiştir. Elde edilen veriler ışığında yaratıcı drama dersinin sosyal hizmetler bölümü lisans öğrencileri üzerinde etkili olduğu ve öğrencilerin tutum puan ortalamalarında artış meydana geldiği belirlenmiştir. Uzaktan eğitim sürecinde kameralar kapalı, sadece dinleyici konumundan çıkarak derste kameralar açık, aktif katılım gösterdikleri ders olduğu için dersin etkili olduğunu ifade etmişlerdir.
Effect of Predeformation on Corrosion Fatigue Crack Growth of Type 316NG Steel in 325°C Deaerated Water
Authors: Xiao Jun , Zheng Yu Qi , Xiao Ting , Wang Hao , Xu Qi
Published: December 2024

The predeformed 316NG (00Cr17Ni12Mo2N) was prepared by cold rolling at room temperature and hot rolling at 400°C. The effect of predeformation on fatigue crack growth both in 325°C deaerated water and room temperature air was investigated. The effect of predeformation on corrosion fatigue crack growth (CFCG) in 325°C deaerated water was much smaller than that on fatigue crack growth. The cold rolling significantly enhanced CFCG rates while the applied ΔK closed to 11 MPa√m or the applied loading frequency decreased to 0.1 Hz. The accelerating effect of hot rolling on CFCG tended to become evident until the predeformation increased to 30%. Dynamic recovery was observed near the corrosion fatigue crack tip in hot-rolled 316NG, which may result in relatively low CFCG rates.
Etrasimod (Velsipity)
Authors: CDA-AMC
Published: December 2024

Reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform nonbinding recommendations that help guide the reimbursement decisions of Canada’s federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses etrasimod (Velsipity), 2 mg film-coated tablet.
Indication: The treatment of adults with moderately to severely active ulcerative colitis who have had an inadequate response, lost response, or were intolerant to either conventional therapy or an advanced treatment.
STUDI LITERATUR TENTANG PENINGKATAN KEMAMPUAN LITERASI MATEMATIKA PADA MODEL PEMBELAJARAN PROBLEM BASED LEARNING
Authors: SURTIKA WIJI , U.S SUPARDI
Published: December 2024

This article presents the results of a literature study regarding improving students' mathematical literacy skills through the application of the Problem Based Learning (PBL) learning model. Mathematical literacy, as an important component in education, includes students' ability to understand, interpret and use mathematical concepts to solve problems in everyday life. The low mathematical literacy abilities of Indonesian students are of particular concern, because this ability has an important role in forming the critical and analytical thinking skills needed in the era of globalization. Therefore, there is a need for innovation in learning methods to improve students' mathematical literacy, one of which is through the PBL model. The PBL learning model is designed to encourage students to think independently, collaborate and be active in solving real problems that are relevant to the learning material. In this model, students are directly involved in the process of problem identification, analysis, and finding solutions, so that they can build a deep understanding and apply mathematical concepts contextually. The study results show that the implementation of structured PBL can increase students' mathematical literacy, critical thinking skills and independence. Therefore, PBL is recommended as an effective method in teaching mathematics, with training support for teachers for optimal implementation.
ABSTRAKArtikel ini menyajikan hasil studi literatur mengenai peningkatan kemampuan literasi matematika siswa melalui penerapan model pembelajaran Problem Based Learning (PBL). Literasi matematika, sebagai salah satu komponen penting dalam pendidikan, mencakup kemampuan siswa dalam memahami, menafsirkan, dan menggunakan konsep matematika untuk memecahkan masalah dalam kehidupan sehari-hari. Rendahnya kemampuan literasi matematika siswa Indonesia menjadi perhatian khusus, karena kemampuan ini memiliki peran penting dalam membentuk keterampilan berpikir kritis dan analitis yang dibutuhkan di era globalisasi. Oleh karena itu, perlu adanya inovasi dalam metode pembelajaran untuk meningkatkan literasi matematika siswa, salah satunya melalui model PBL. Model pembelajaran PBL dirancang untuk mendorong siswa berpikir mandiri, berkolaborasi, dan aktif dalam memecahkan masalah nyata yang relevan dengan materi pembelajaran. Dalam model ini, siswa dilibatkan secara langsung dalam proses identifikasi masalah, analisis, dan pencarian solusi, sehingga mereka dapat membangun pemahaman yang mendalam dan menerapkan konsep matematika secara kontekstual. Hasil studi menunjukkan bahwa penerapan PBL yang terstruktur dapat meningkatkan literasi matematika, keterampilan berpikir kritis, dan kemandirian siswa. Oleh karena itu, PBL direkomendasikan sebagai metode efektif dalam pembelajaran matematika, dengan dukungan pelatihan bagi guru untuk penerapan yang optimal.
AS INTERSECÇÕES ENTRE AS POLÍTICAS PÚBLICAS: O PAPEL DO PNAE DENTRO DAS METAS DO PNE
Authors: Nascimento Marilande Porcino Pereira , Pinho Alexandra Moreno
Published: December 2024

Analisou-se a relação entre duas políticas públicas fundamentais: Plano Nacional de Educação (PNE) e Programa Nacional de Alimentação escolar (PNAE) e os entraves que dificultaram o êxito de tais políticas entre 2014-2024, no alcance de suas metas. Com ênfase nas metas 1,2 e 3 que buscam a universalização da educação, destacou-se pontos que dialogam com ambos programas, os quais demonstram que dentre os fatores que contribuíram para que as metas não sejam alcançadas está a falta de investimento na educação, sendo a merenda escolar um aspecto importante para o acesso e a permanência do alunado nas instituições de ensino. De acordo com uma pesquisa bibliográfica, foi possível desvelar fatores que contribuíram nos resultados existentes, com isso se faz necessário repensar e reestruturar as formas de intervenção.
O BAIXO RENDIMENTO DOS ALUNOS QUE APRESENTAM VULNERABILIDADE SOCIAL
Authors: Almeida Josineide Eliodoro de , Gusmão Diogenes
Published: December 2024

Esta dissertação aborda o ambiente escolar como meio social no qual as crianças passam a maior parte do tempo, por ser um espaço compreendido como um luga privilegiado para o aprendizado. Anualmente ingressam nas escolas públicas do município um número extremamente grande de alunos vindos de comunidades carentes e vulneráveis, com histórias de vida que, em muitos dos casos faz parte o trabalho infantil, a negligência, maus-tratos, violência e exploração, tudo isso associado a extrema pobreza, desemprego e drogas onde suas famílias estão envolvidas. Muitos desses alunos apresentam algum tipo de dificuldade principalmente ligadas à aprendizagem e desempenho escolar tornando bastante questionável a relação entre condição de vida e o rendimento obtidos por eles, destacando não só a família, mas também as ações das escolas e a prática docente para minimizar esse baixo índice de aprendizagem. Tem-se como objetivo analisar as estratégias de intervenções dos professores que lecionam nas séries finais do ensino fundamental I com alunos em situações de vulnerabilidade social de uma instituição de ensino da rede municipal. O aporte metodológico foi do tipo descritivo e exploratório, hipotético-dedutivo, com recorte transversal e qualitativo através de questionários semiestruturados. Através de autores base nacionais e internacionais como: Bourdieu (2014), Vygotsky (2015), Piaget (2017), Ferreira (2020), Ambramavay (2015), Libâneo (2015), Carara (2016), Silva (2017), Bitencourt (2019), Gadotti (2014), Azevedo (2019), entre outros.
Multi-model effective radiative forcing of the 2020 sulfur cap for shipping
Authors: Skeie Ragnhild Bieltvedt , Byrom Rachael , Hodnebrog Øivind , Jouan Caroline , Myhre Gunnar
Published: December 2024

Abstract. New regulations of sulfur emissions from shipping were introduced in 2020, reducing emissions of SO2 from international shipping by ∼ 80 %. As SO2 is an aerosol precursor, this drop in emissions over the ocean will weaken the total aerosol effective radiative forcing (ERF) that has historically masked an uncertain fraction of the warming due to the increased concentration of greenhouse gases in the atmosphere. Here, we use four global climate models and a chemical transport model to calculate the ERF resulting from an 80 % reduction in SO2 emissions from international shipping relative to 2019 emission estimates. The individual model means range from 0.06 to 0.09 W m−2, corresponding to the ERF resulting from the increase in CO2 concentration over the last 2 to 3 years. The full uncertainty in the ERF due to the new regulation is not quantified but will very likely be high considering the contribution of uncertainties in shipping SO2 emissions, the sulfur cycle, the modelling of cloud adjustments and the impact of interannual variability on the method for calculating radiative forcing.
Consideration of the cloud motion for aircraft-based stereographically derived cloud geometry and cloud top heights
Authors: Volkmer Lea , Kölling Tobias , Zinner Tobias , Mayer Bernhard
Published: December 2024

Abstract. Cloud geometry and in particular cloud top heights can be derived from 2-D camera measurements by applying a stereographic method to data from an overflight over a scene of clouds (see, e.g., Kölling et al., 2019). Although airplane overpasses are relatively fast, cloud motion with the wind is important and can result in errors in the cloud localization. Here, the impact of the wind is investigated using the method from Kölling et al. (2019) for measurements of the airborne hyperspectral imaging system spectrometer of the Munich Aerosol Cloud Scanner (specMACS). Further, a method for cloud motion correction using model winds from the European Centre for Medium-Range Weather Forecasts (ECMWF) is presented. It is shown that the update is important as the original algorithm without the cloud motion correction can over- or underestimate the cloud top heights by several hundred meters, depending on the wind speed and the relative wind direction. This is validated using data from the Elucidating the role of clouds–circulation coupling in climate (EUREC4A) campaign and realistic 3-D radiative transfer simulations. From the comparison of the derived cloud top heights with the expected ones from the model input, an average accuracy of the cloud top heights of less than (20±140) m (mean deviation and 1 standard deviation) is estimated for the updated method.
Hydrography and circulation below Fimbulisen Ice Shelf, East Antarctica, from 14 years of moored observations
Authors: Lauber Julius , Hattermann Tore , de Steur Laura , Darelius Elin , Fransson Agneta
Published: December 2024

Abstract. Future mass loss from the East Antarctic Ice Sheet represents a major uncertainty in projections of future sea level rise. Recent studies have highlighted the potential vulnerability of the East Antarctic Ice Sheet to atmospheric and oceanic changes, but long-term observations inside the ice shelf cavities are rare. Here, we present new insights from observations from three oceanic moorings below Fimbulisen Ice Shelf from 2009 to 2023. We examine the characteristics of intrusions of modified Warm Deep Water (mWDW) across a sill connecting the cavity to the open ocean and investigate seasonal variability of the circulation and water masses inside the cavity using an optimum multiparameter analysis. In autumn, the water below the 345 m deep central part of the ice shelf is composed of up to 30 % solar-heated, buoyant Antarctic Surface Water (ASW), separating colder Ice Shelf Water from the ice base and affecting the cavity circulation on seasonal timescales. At depth, the occurrence of mWDW is associated with the advection of cyclonic eddies across the sill into the cavity. These eddies reach up to the ice base. The warm intrusions are observed most often from January to March and from September to November, and traces of mWDW-derived meltwater close to the ice base imply an overturning of these warm intrusions inside the cavity. We suggest that this timing is set by both the offshore thermocline depth and the interactions of the Antarctic Slope Current with the ice shelf topography over the continental slope. Our findings provide a better understanding of the interplay between shallow inflows of ASW contributions and deep inflows of mWDW for basal melting at Fimbulisen Ice Shelf, with implications for the potential vulnerability of the ice shelf to climate change.
MESOSCALE EDDIES OF THE BALTIC SEA ACCORDING TO THE PHYSCIAL REANALYSIS
Authors:   Saint Petersburg State University, TRAVKIN V.S. ,   Zubov State Oceanographic Institute, TIKHONOVA N.A. ,   Saint Petersburg State University,   Zubov State Oceanographic Institute, ZAKHARCHUK E.A. ,   Saint Petersburg State University
Published: December 2024

The mesoscale eddies of the Baltic Sea are analyzed based on the algorithm for automatic identification of eddies and the BALTICSEA_REANALYSIS_PHY_003_011 data. It is shown that most of mesoscale eddies have an amplitude (a level difference from the center to the boundary of an eddy) of 0.05-0.20 m, a radius of 5-10 km, and a lifetime of 2-3 days. From 1993 to 2020, 120000 eddies were detected, the number of cyclones exceeded the number of anticyclones, and anticyclones had a larger radius, geostrophic velocity, and lifetime. On average, Baltic eddies have a geostrophic velocity of about 6.5 cm/s and move for 4 km per day. The concentration areas of eddies have been detected for cyclones and anticyclones, and their general circulation has been also shown. Long-lived eddies make up only 1.5% of the total number of eddies, and their movement is highly influenced by topography. The average ratio of the major to minor semi-axes of Baltic eddies is 1.58. Their amplitude is maximal in the autumn-winter period, while their number and radius are maximal in summer. For the amplitude and number of eddies and their area, there are a significant interannual variability and significant linear trends. Eddies on average occupy 2% of the Baltic Sea area in winter and 4% in summer.
CHARACTERISTICS OF THE MOSCOW HEAT ISLAND AND SKILL SCORES OF ITS SIMULATION WITH THE COSMO-RU1-MSK MODEL BASED ON MOSEСOMONITORING OBSERVATIONS
Authors:   Hydrometeorological Research Center of the Russian Federation, KUZNETSOVA I.N. , SEMUTNIKOVA E.G. ,   Mosecomonitoring State Nature Protection Organization, LEZINA E.A. ,   Mosecomonitoring State Nature Protection Organization, ZAKHAROVA P.V. ,   Mosecomonitoring State Nature Protection Organization, TKACHEVA YU.V. ,   Hydrometeorological Research Center of the Russian Federation, VARENTSOV M.I. ,   Hydrometeorological Research Center of the Russian Federation,   Research Computing Center, Lomonosov Moscow State University,   Russian State Hydrometeorological University, TARASOVA M.A. ,   Hydrometeorological Research Center of the Russian Federation,   Research Computing Center, Lomonosov Moscow State University,   Lomonosov Moscow State University, Faculty of Geography, RIVIN G.S. ,   Hydrometeorological Research Center of the Russian Federation, KHRYKINA E.A. ,   Hydrometeorological Research Center of the Russian Federation
Published: December 2024

The temporal and spatial variations in surface air temperature in Moscow are analyzed based on multiyear (2008-2022) observations from the Mosecomonitoring network for the megacity environment quality monitoring. The authors propose to represent the urban heat island (UHI) as zones encircling the warmest territory in the center, highlighting the urban periphery and outskirts, near suburbs, a background area, and an urban cold island in the Losiny Ostrov Park. Zonal temperature reflects the internal structure of the UHI and its dynamics, which allows focusing on individual areas of the megalopolis when developing measures to preserve air quality. The annual mean UHI magnitude in the center of Moscow has increased by 0.5°C over the past 10 years and reached 2.5°C. Significant interannual, seasonal, and interdaily variability in the daily mean and nighttime UHI magnitude is demonstrated. The relevance of estimating an anthropogenic component of the UHI based on the values of the nocturnal heat anomaly is emphasized...
Remembering John Clarke
Authors: Student Success Editorial Team
Published: December 2024

Professor John Clarke was a founding editor of Student Success (previously titled The First Year in Higher Education) and later Advisory Board Member.
We thank our colleagues who have provided their reflections on working with John.
Extensão universitária no ambiente virtual
Authors: Reiter Ana Clara Waintuch , Novelli Daniela
Published: December 2024

As ações de extensão passaram por um processo de curricularização. Dentre as mudanças propostas tem-se a indicação do ideal de atuação: o espaço físico. Esta foi adaptada em razão das mudanças geradas pela pandemia da Covid-19. Foi essencial adequar os projetos de extensão às tecnologias digitais, à dinâmica online e à cibercultura. Este artigo investiga como 2 das diretrizes da extensão - a interação dialógica e a formação cidadã dos estudantes - foram impactadas pela adoção destes ambientes como local de atuação do projeto Numma, do Curso de Moda da Udesc. Assim, foram realizados um mapeamento de projetos de extensão deste curso, um levantamento das ações realizadas em 2022 e a categorização sobre o local de realização de cada ação. Em seguida, foi realizada uma análise qualitativa das ações do Numma. No final, observou-se como se desdobraram as mudanças, quais se alinham com a dinâmica digital, quais não, e quais podem ser os caminhos para aplicar estas ações no ambiente online.
Palavras-chave: Ambiente virtual. Comunicação. Extensão. Moda.
Posgrado e Internacionalización en la Argentina
Authors: Araujo Sonia Marcela
Published: December 2024

Este artículo está vinculado al proyecto de extensión organizado por el Programa de Posgrado en Educación - PPGE/FE/UFG titulado 'Educación en tiempos de pandemia: los desafíos de la internacionalización', que contó con disertantes de Mozambique, México, Canadá, Portugal, Argentina y España El evento fue coordinado por los profesores Dr. Wilson Alves de Paiva, Dra. Marilza Vanessa Rosa Suanno y Prof. Maria Margarida Machado y está disponible en el Canal de YouTube UFG -Graduación e internacionalización en Argentina. 
Palabras clave: Extensión. Internacionalización. Posgraduación.
Development of the Leisure Time Attitude Scale for Children with Visual Impairment
Authors: Haylı Çiğdem Müge , Chung Seockhoon , Kösem Dilek Demir , Karataş Ramazan
Published: December 2024

This study was conducted to develop a leisure time attitude scale for children with visual impairment. The sample of the study consisted of 529 children with visual impairment. With the consent of the children's parents and themselves, they were asked to answer the sociodemographic information form and the list of questions in the leisure time attitude scale for children with visual impairment, which was created by the researcher team based on expert opinion. Cronbach's alpha and Omega coefficients of the scale were found to be 0.94. In the correlation coefficient used as test-retest reliability method; a moderate and high level positive relationship was found between the scores obtained from the first and second applications (0,74; 0,65; 0,72; 0,66). According to the criterion validity findings; a moderate positive and significant relationship was found between the scores obtained from the leisure time attitude scale for children with visual impairment and the general leisure time attitude scale (p<0.01). These results showed that the leisure time attitude scale for children with visual impairment is a valid and reliable new scale.
Navigating Learning Differences: The Role of Mind Mapping in Fostering Inclusivity in Science Education
Authors: Wijiastuti Asri , Rofiah Khofidotur , Minarsih Ni Made Marlin
Published: December 2024

This study thoroughly scrutinizes the utilization and influence of mind mapping (MM), as a teaching tool in science education, particularly focusing on its application for students with special educational needs (SEN). We investigated how employing MM techniques impacted students’ learning abilities through mixed methods, using quasi-experimental design and semi-structured interviews. The findings revealed that the comparison scores before (pretest) and after (posttest) the intervention using Popplet as a MM tool showed improvements for both control and experimental student groups. Additionally, by utilizing thematic analysis to explore students’ experiences using MM, two main themes emerged: (1) adaptive learning strategies and (2) between individual and collaborative learning Feedback from students highlighted how MM can enhance memory and presentation skills, although issues related to design features and accessibility may challenges students with SEN. This paper is the first research exploring how mind mapping is accessible for Indonesian inclusive higher education, particularly for students with visual impairments. Physical guidance and verbal instruction were effectively used to explain the mind mapping concept and the spatial representation and relationship for students with visual impairments. This study emphasizes the significance of utilizing tools that cater to diverse learning styles and requirements to promote inclusivity in educational practices.
A Study on the Impact of Self-Efficacy on Teachers' Attitude towards Mainstreaming of Children with Disabilities
Authors: Thapliyal Rubee Mamgain
Published: December 2024

Implementation of inclusive practices at the grassroots level is highly recommended to investigate the nature of teachers' attitudes, whereas high levels of self-efficacy tend to exhibit the most favorable positive attitudes towards inclusive education. Thus, it is crucial to understand how self-efficacy affects teachers' attitudes toward inclusive classroom settings. This study was designed to determine the individual contribution of self-efficacy in predicting teachers' attitudes toward mainstreaming of children with disabilities in Gwalior district, Madhya Pradesh, India. Additionally, the study intended to investigate the collective influence of gender, school locality, and teaching experience on self-efficacy and attitudes. Using teacher efficacy for inclusive practices (TEIP) and teacher attitudes toward inclusive education (TASTIE) scales, data were collected from 613 government elementary school teachers. Parametric statistics, three-way ANOVA, and regression analysis were used to analyze data, and results showed that the level of self-efficacy was not significantly affected by gender, school locality, and teaching experience nor by the interaction of these variables. However, teachers' attitudes were significantly affected by the locale of schools, with urban teachers exhibiting more favorable attitudes than their rural counterparts. While there was a significant positive correlation between self-efficacy and teachers' attitudes, the contribution of self-efficacy to predicting attitudes was relatively low.
DISRUPTION OF HEMOSTASIS IN THE PATHOGENESIS OF ISCHEMIC STROKE
Authors: Tsybikov N. N. , Fefelova E. V. , Butin E. V. , Tsydypova A. E.
Published: December 2024

This review article presents current information on the pathogenetic features of hemostasis in cerebral ischemic stroke based on the analysis of scientific articles indexed in PubMed and Web of Science databases. Ischemic stroke is a sudden neurological failure due to acute focal cerebral ischemia leading to cerebral infarction. The role of hemostasis disorders in the pathogenesis of ischemic stroke has been much less publicized in scientific circles, and the dynamics of disorders and early signs of activation of the blood coagulation system, including the development of hemorrhagic transformation and secondary vasospasm, have not been sufficiently studied.
THE OPPORTUNITY OF MONITORING AND OPTIMIZATION OF THE VOLEMIC STATUS IN PATIENTS WITH SEPSIS
Authors: Yamshchikov O. N. , Zakurnaeva E. I. , Marchenko A. P. , Emelyanov S. A. , Arhipov K. P. , Marchenko N. A.
Published: December 2024

Relevance. The relevance of the problem of the volemic status (VS) correction in patients with sepsis, especially with septic shock and multiple organ failure is beyond doubt, because in this condition there are always significant and life-threatening changes in homeostasis, especially in the circulatory system. At the same time, the percent of deaths remains high, and uncertainty in the pathophysiological mechanisms and an erased clinical picture can lead to untimely diagnosis and delayed correction of circulating blood volume (CBV).

Aim of research. To analyze and summarize current concepts about the assessment of CBV in sepsis and septic shock. To identify current approaches to infusion therapy in this pathology in order to increase the efficiency of treatment and knowledge of specialists.

Materials and methods. During writing the article, the search for literary sources was carried out in the databases: PubMed, eLibrary, CyberLeninka over the past 5 years, as well as from earlier sources that have not lost their relevance. At the same time, free access to the full content of publications was used in accordance with the subject of the review.

Conclusion. The choice of infusion therapy tactics for patients with sepsis and polymorbidity may present significant difficulties due to the limited number of methods for monitoring and correcting volemic status. At the same time, the difficulty of making a decision is due to the multifactorial nature of the parameters and the inconsistency of the results obtained. In this situation, the result of treatment can be improved by using a combined analysis of parameters, prioritizing dynamic rather than static indicators. Methods of research and control of VS based on ultrasound technologies are more accessible and preferable in use for most medical preventive institutions (MPI) to determine the strategy of infusion therapy in the treatment of sepsis. The topic of control and correction of volemic status needs further research.
BIOMARKERS OF ACUTE KIDNEY INJURY OF BLOOD SERUM IN PATIENTS WITH THERMAL SKIN BURNS
Authors: Konovalova A. A. , Tsepelev V. L.
Published: December 2024

The aim: to evaluate the dynamics of changes in the level of biomarkers of acute kidney injury – lipocalin and cystatin C in blood serum in patients with thermal skin burns.

Materials and methods. The study included 74 patients with thermal skin burns of I-III degree with a skin lesion area of more than 25%, of which at least 15% are deep burns. Serum creatinine levels were determined using the kinetic Jaffe method. Lidocaine and cystatin C concentrations were studied by multiplex analysis on a flow cytofluorimeter.

Results. It was found that the concentration of cystatin C in the blood serum during burn shock increases by 1,9 times, with burn toxemia and septicotoxemia - by 1,5 times in relation to the control group. The level of lipocalin in the blood serum of patients with thermal skin burns during the shock period increases by 5,5 times compared to the control group. During the period of burn toxemia and septicotoxemia, lidocaine concentration remained at a high level and exceeded the control values by 4,4 and 3,6 times, respectively.

Conclusion. Lipocaine and cystatin C can be considered as early biomarkers of acute kidney injury in patients with thermal skin burns.
Delayed breast reconstruction with the thoracodorsal flap and endoprosthesis after complex treatment of breast cancer
Authors: Bosieva A. R. , Zikiryakhodzhaev A. D. , Usov F. N. , Khakimova Sh. G. , Efanov V. V.
Published: December 2024

Breast reconstruction with a thoracodorsal flap (TDF) in combination with a tissue expander/implant is a wellestablished technique.

The purpose of the study was to present current data on the results of delayed breast reconstruction with thoracodorsal flap and tissue expander after combined/complex treatment in patients with breast cancer.

Material and methods. The search for relevant sources was carried out in the PubMed, Cochrane Library, E-library systems, publications from 2014 to 2022 were studied. Delayed breast reconstruction using TDF in combination with a tissue expander/implant is a reliable method of reconstruction for the group of patients who have previously undergone radical mastectomy or adjuvant external beam radiation therapy in terms of combined/complex treatment of breast cancer, allowing to achieve good and excellent aesthetic results with a low incidence of surgical complications.

Results and discussion. The use of the latissimus dorsi flap is a reliable and universal method of breast reconstruction, it allows achieving good and excellent aesthetic results, high patient satisfaction. Patients with a low body mass index or obesity, a history of abdominal surgery, including abdominoplasty, are not candidates for reconstruction using anterior abdominal wall flaps, and therefore the only possible method of breast reconstruction for them is the method using the TDF. In addition, the use of the TDF may be most appropriate for women who are planning a pregnancy in the future and for whom the use of anterior abdominal wall flaps will not be an optimal method of reconstruction due to reduced abdominal wall compliance. Other reasons why the use of TDF is the method of choice for many surgeons are the possibility of closing the donor site regardless of the size of the skin flap taken, the possibility of closing such defects of the mammary gland as extrusions, protrusions, in case of insufficiency of the skin cover after skin-preserving mastectomies.

Conclusion. The use of the latissimus dorsi flap is a reliable and universal method of breast reconstruction, it allows achieving good and excellent aesthetic results, a high degree of patient satisfaction.
Pathomorphologic features of the structure of hyperextensible eyelid tissues
Authors: Grishchenko S. V. , Borhunova E. N. , Filatova I. A. , Kartasheva A. F. , Ushano G. T.
Published: December 2024

Purpose of a study: to identify pathomorphological features of hyperextensible eyelids for planning and predicting the outcome of blepharoplasty.

Material and methods. 352 patients (100%) with involutional eyelid changes, indications for aesthetic blepharoplasty were examined. Out of the total number of the study participants 87 patients (24.7%) had clinical signs of hyperextensible eyelids (HES): ‘festoons’, hypotonia of the lower eyelids with positive ‘pinch test’, pronounced skin folds and free easy displacement of lax tissues of eyelids, face and neck, pseudoblepharochalasis, ptosis of eyebrows, dystopia of the external corners of the eyes and risk factors of postoperative eyelid retraction. We analysed surgical biopsies of the skin, circular muscle of the eye, and tarsal plate after blepharoplasty operations from 28 patients aged from 41 to 60 years with clinical manifestations of HES combined with hyperelastosis (17 patients) and blepharochalasis (11 patients).

Results. Typical morphological signs of hyperextensibility of the eyelid skin, circular muscle of the eye, and tarsal plate have been established: sclerosis, focal dystrophy of the intercellular substance, moderate macrophagelymphocytic infiltration with eosinophils markers of chronic inflammation, and necrosis of adipocytes and meibomian glands. In HES in eyelid skin elastic fibres are registered in small quantity, fragmented, single with signs of destruction; in blepharochalasis they are absent; collagen fibres are significantly thinned, which leads to a decrease in elasticity, tone and turgor of the skin.

Conclusion. Morphological changes in tissue structure in HES combined with blepharochalasis and hyperelasticity directly correlate with clinical manifestations of HES. It is advisable to identify such patients at the stage of blepharoplasty planning, classify them as a risk group for secondary postoperative deformities and apply to them gentle blepharoplasty techniques with elements of eyelid strengthening.
Comparative evaluation of the quality of life of patients after mastectomy and non-flapped breast reconstructions for cancer
Authors: Petrosyants S. V. , Aydemirov A. N. , Ivanov D. V. , Sergeev D. I. , Rovenskikh D. N.
Published: December 2024

Purpose of the study: to compare the quality of life of patients who underwent mastectomy and non-flapped breast reconstructions for cancer.

The study included 90 patients, diagnosed with breast cancer 0–IIA st. T1–2N0M0. The minimum age of the patients was 30 years old, the maximum was 65 years, the average age was (49.76 ± 8.54) years old. Patients were divided into three groups of 30 women depending on the type of surgical treatment of the tumor and breast reconstruction: 1st group – Madden surgery with a subsectoral expander installation and replacement with a silicone endoprosthesis, 2nd group – Madden surgery with prepectoral expander installation, staged lipofilling and replacement with silicone endoprosthesis, 3rd group – radical subcutaneous mastectomy with one-stage prepectoral breast reconstruction. The quality of life was assessed using a set of Breast-Q scales.

The data obtained make it possible to draw conclusions about the effectiveness of subcutaneous mastectomy with one-stage prepectoral breast reconstruction according to the method proposed by the authors due to the tendency to a more intensive increase of the quality of life of patients at the stages of rehabilitation in such aspects as psychosocial, physical and sexual well-being.
Examining the Role of Organizational Culture in Shaping Security Practices: A Case Study of Tertiary Institutions
Authors: Yusuf Abubakar
Published: December 2024

This study investigates the critical role of the human factor in enhancing organizational cybersecurity resilience, particularly within the context of tertiary institutions in Nigeria. As organizations increasingly depend on digital technologies, understanding how employee knowledge, behavior, and awareness impact information security is paramount. The research highlights the significant contribution of human error to security breaches, underscoring that even the most sophisticated technological defenses are vulnerable when individuals do not adhere to security protocols. Utilizing a comprehensive literature review, the study examines the implications of human behavior, including negligence and social engineering, on organizational security outcomes. Key findings indicate that insufficient training, lack of supervision, and poor understanding of security policies exacerbate vulnerabilities. Recommendations include implementing robust security awareness programs and ensuring that only qualified personnel teach keyboarding skills, as these practices can mitigate risks. Ultimately, the research advocates for a socio-technical approach to cybersecurity, emphasizing the need for collaboration between technical solutions and human factors to foster a more secure operational environment in the educational sector.
Evaluation of Adrenergic Neuron Inhibition in Patients with Uncontrolled Hypertension
Authors: Mawafak Seba , Bashar Zainulabdeen Shn , A Najem Kais , Mayyas Amal , I Oraibi Amjad , Salam Al-Tameemi Zahraa , A. Al-hussaniy Hany , Akeel naji Fatima , Hikmat Alburghaif Ali , K. Al iraqi Mohammed , akeel Naji Meena
Published: December 2024

Background: Uncontrolled hypertension increases the risk of cardiovascular illnesses and death, among other serious health problems. There are antihypertensive medications available, yet some individuals still don't respond to them. Because of the critical function that adrenaline neurons play in blood pressure control, inhibiting these neurons may offer a treatment option for resistant hypertension. Aim: This study conducted to Evaluation of the Efficacy of nanotecology based therapy as Adrenergic Neurons Inhibition in Patients with Uncontrolled Hypertension. Method: We was conducted a review article in the role of adrenergic blocker by medication or by surgery, knowing that we was used keywords "Antihypertensive Agents" and "nanotechnology based therapy," , "Adrenergic Neurons" , "Ganglia", "Spinal" and "Hypertensive Crisis" . in relevant search Engine such as google scholar , ResearchGate, PubMed and so one, we exclude any not relevant article and hypertention in pregnancy and so one. Result: The nanotechnology-enhanced treatment group showed a significant reduction in systolic and diastolic blood pressure compared to the control group. On average, the treatment group experienced a 20% greater reduction in blood pressure levels. Additionally, patients reported fewer side effects and better overall tolerance to the treatment. Conclusion: Nanotechnology-enhanced adrenergic neuron inhibition demonstrates substantial promise in managing uncontrolled hypertension. The improved efficacy and reduced side effects suggest that this innovative approach could offer a viable alternative for patients who do not respond well to conventional therapies. Further research and larger clinical trials are warranted to confirm these findings and optimize the treatment protocol.
Adaptive high flow oxygen therapy: New concept
Authors: Ongsupankul Sorawit , Dhupa Achal , Daoud Ehab
Published: December 2024

Background
High-flow oxygen therapy (HFOT) is increasingly utilized in clinical settings due to its potential to improve oxygenation, patient comfort and possibly outcomes in different respiratory failure states. The potential benefits of HFOT include matching the patients’ flow to reduce the work of breathing, creating airway pressure, humidification, and reducing dead space.
However, it has some shortcomings including the difficulty of setting the flow to match patients’ efforts, the continuous flow does not represent normal physiologic spontaneous breathing, and the lack of traditional airway pressure monitoring.
We are testing a new adaptive high-flow oxygen delivery technique “Auto Positive Airway Pressure” (Auto-PAP) where the flow delivered from the ventilator adapts to patients’ efforts taking into consideration the patients’ dead space
Methods
A bench study using ASL 5000 simulator, we created a single-compartment active model of a male with IBW 70 kg, with compliance of 40 ml/cmH20 and resistance of 10 cmH2o/L/s. The respiratory rate was set at 20 bpm, with inspiratory time of 1 second. Muscle pressure (Pmus) was gradually increased by increments of 5 cmH2O from 5 to 50. Adaptive high flow mode (Auto PAP) using a Bellavista 1000e ventilator (Zoll MA, USA) using a large bore nasal cannula to an adult-sized mannequin nose that was connected to the lung simulator. Pearson correlation coefficient was used in correlating the Pmus to the maximum, mean flow and pressure, and the simulator to the ventilator flow.
Results
There was significant strong correlation between the Pmus and the maximum flow R: 0.949, CI (0.794, 0.988) P < 0.001, and mean flow R: 0.955, P < 0.001, CI (0.816, 0.989). There was a significant strong correlation with Pmus and the maximum pressure R: 0.972, P < 0.001, CI (0.883, 0.993) and mean pressure R: 0.942, P < 0.001, CI (0.768, 0.986). There was significant strong correlation between the simulator and the ventilator flow R: 0.961, P < 0.001. There was significant strong correlation between the simulator and the ventilator mean pressure R: 0.951, P < 0.001, CI (0.799, 0.988). There was significant strong correlation between the mean flow from the ventilator to the mean airway pressure measured at the simulator R: 0.936, P < 0.001 CI (0.747, 0.985).
Conclusion
Results suggest a significant correlation between the flow and pressure from adaptive HFOT and the patient muscle effort, indicating that the flow and pressure increase in response to the patients’ effort. This may reduce respiratory muscle workload compared to traditional high flow oxygen therapies and reduce the need for multiple manual adjustment of the flow. These findings underscore the potential of this technology to enhance respiratory support while minimizing patient effort.
Further research is warranted to validate these findings in real patient cohorts in diverse clinical scenarios.

Keywords: High flow oxygen therapy, mean flow, mean pressure
“PREVALENCIA DE MICROFILAREMIA DE Dirofilaria immitis EN PERROS DOMÉSTICOS DE LA COMUNA OLÓN DE LA PROVINCIA DE SANTA ELENA”
Authors: Parra-Guayasamín Sandra Gabriela , Tuarez Villón Kleiner Agustín , Orrala Mendoza Angela Estefanía
Published: December 2024

La Dirofilariasis es una patología transmitida por el nemátodo Dirofilaria immitis, los vectores que ayudan a su transmisión son los mosquitos Culex, Aedes, Anopheles o Mansonia. Se encontró con este estudio la prevalencia de microfilarias en perros domésticos, por medio de un muestreo dirigido, se recogieron muestras de sangre de 30 perros, estas fueron procesadas mediante la   técnica   de   identificación   microscópica de microfilarias denominada “técnica de Knott”, se obtuvo 10 casos positivos, estableciendo una prevalencia del 33.3%.  Los datos obtenidos se procesaron por la prueba paramétrica de Chi Cuadrado, mediante el software SPSS, dando como resultado que la variable desparasitación (interna) presentó datos estadísticamente significativos, demostrando que existe relación entre la variable y la presencia de microfilarias en circulación sanguínea de perros domésticos, sino más bien de la periodicidad de desparasitación que se le brinde a la mascota.
Of Animals and Men (A Linguocultural Approach to Serbian and Croatian Phraseology)
Authors: Stefanov Martin
Published: December 2024

This paper analyzes the phraseological units which consist
of a noun that denotes an animal (or body part of an animal), and which basic
structure represents an interaction between a man and an animal. However, in
this text the phraseological material is approached from a linguocultural point
of view and, depending on the meaning of the structural base, 8 thematic groups
are distinguished. This approach is motivated by the understanding that culturally
significant information can be carried by all components of the structural base of the
phraseological units that reveal the attitude of man towards animals.