bluuebunny/crossref_metadata_2025 huggingface dataset:
Grey Cast Iron Brake Discs Laser Cladded with Nickel-Tungsten Carbide—Friction, Wear and Airborne Wear Particle Emission
Authors: Dizdar Senad , Lyu Yezhe , Lampa Conny , Olofsson Ulf
Published: June 2020

Airborne wear particle emission has been investigated in a pin-on-disc tribometer equipped with particle analysis equipment. The pins are cut out from commercial powder metallurgy automotive brake pads as with and without copper content. The discs are cut out from a commercial grey cast iron automotive brake disc as cut out and as in addition to a laser cladded with a powder mix of Ni-self fluxing alloy + 60% spheroidized fused tungsten carbide and then fine-ground. Dry sliding wear testing runs under a contact pressure of 0.6 MPa, sliding velocity of 2 m/s and a total sliding distance of 14,400 m. The test results show both wear and particle emission improvement by using laser cladded discs. The laser cladded discs in comparison to the reference grey cast iron discs do not alter pin wear substantially but achieves halved mass loss and quartered specific wear. Comparing in the same way, the friction coefficient increases from 0.5 to 0.6, and the particle number concentration decreases from over 100 to some 70 (1/cm3) and the partition of particles below 7 µm is approximately halved.
Characterizing Olfactory Function in Children with Autism Spectrum Disorder and Children with Sensory Processing Dysfunction
Authors: Sweigert Julia R. , St. John Tanya , Begay Kristin Kawena , Davis Greg E. , Munson Jeffrey , Shankland Eric , Estes Annette , Dager Stephen R. , Kleinhans Natalia M.
Published: June 2020

Abnormalities in olfactory function have been identified in a number of neurological and psychiatric disorders, including Parkinson’s disease and schizophrenia. However, little is known about olfactory function in autism spectrum disorder (ASD). The present study aims to assess the olfactory profiles of children with ASD, compared to an age- and sex-matched comparison group of typically developing children and a second clinical control group consisting of non-ASD children with sensory processing dysfunction (SPD). Participants completed a battery of sensory and behavioral assessments including olfactory tasks (Sniffin’ Sticks Threshold Test and self-reported valence ratings for two target odorants (phenylethyl alcohol and vanillin) and the University of Pennsylvania Smell Identification Test), and an autism evaluation (Autism Diagnostic Observation Schedule-2). Children with ASD showed intact odor detection with reduced odor identification ability. Poor odor identification was significantly correlated with autism symptom severity. Children with SPD demonstrated reduced odor detection and identification ability. These findings provide evidence for differential patterns of smell processing among ASD and non-ASD neurodevelopmental disorders. Future studies are needed to determine whether the association of impaired olfaction and increased autism symptoms is due to shared etiology.
Selected Papers from the 2nd Edition of Global Conference on Catalysis, Chemical Engineering and Technology (CAT 2018)
Authors: Dzwigaj Stanislaw , Len Christophe
Published: June 2020

The present Special Issue concerns the papers which have been presented at the second edition of the Global Conference on Catalysis, Chemical Engineering & Technology (CAT 2018) that promote linkage of the catalytic science, engineering and technology [...]
Catalysts for Syngas Production
Authors: Ereña Javier
Published: June 2020

Synthesis gas (or syngas) is a mixture of hydrogen and carbon monoxide, that may be obtained from alternative sources to oil, such as natural gas, coal, biomass, organic wastes, etc [...]
The Spinning Voltage Influence on the Growth of ZnO-rGO Nanorods for Photocatalytic Degradation of Methyl Orange Dye
Authors: Ramos Pierre G. , Luyo Clemente , Sánchez Luis A. , Gomez Enrique D. , Rodriguez Juan M.
Published: June 2020

In this work, well-designed zinc oxide-reduced graphene oxide (ZnO-rGO) nanorods (NRs) were synthesized by a hydrothermal method using electrospun ZnO-rGO seed layers. The ZnO-rGO seed layers were fabricated on fluorine-doped tin oxide (FTO) glass substrates through calcined of electrospun nanofibers at 400 °C in the air for 1 h. The nanofibers were prepared by electrospinning different spinning voltages and a spinning solution containing zinc acetate, polyvinyl pyrrolidone, and 0.2 wt% rGO. From a detailed characterization using various analytical techniques, for instance, X-ray diffraction (XRD), field emission scanning electron microscopy (SEM), Raman spectroscopy, photoluminescence (PL), and X-ray photoelectron spectroscopy (XPS), the dependence of the structure, morphology, and optical properties of the ZnO-rGO NRs was demonstrated. The photocatalytic activities of ZnO-rGO nanorods were evaluated through the degradation of dye methyl orange (MO). The results show that the change of spinning voltages and the coupling of rGO with ZnO improved photodecomposition efficiency as compared to pure ZnO. The highest photocatalytic efficiency was obtained for the ZnO-rGO NRs prepared with a spinning voltage of 40 kV.
Dimensions of Phyllostomid Bat Diversity and Assemblage Composition in a Tropical Forest-Agricultural Landscape
Authors: Carrasco-Rueda Farah , Loiselle Bette A.
Published: June 2020

Tropical rainforests are suffering rapid habitat loss with large extensions of land transformed into agriculture. We wanted to know whether the type of agricultural activity in forest-agricultural landscapes affects how species composition as well as taxonomic and functional dimensions of diversity respond. We worked in the Amazon forests of southeast Peru and used bats as model organisms. We sampled mosaics characterized by forest adjacent to papaya plantations or cattle pastures. At each sampling site we established a transect in each of the three different vegetation types: forest interior, forest edge and agricultural land. We found that vegetation type was a better predictor of species composition than the type of agricultural land present. Vegetation structure characteristics explained differences in bat species composition between forest interior and edge. Agricultural land type chosen was not irrelevant as we found higher estimated species richness in papaya than in pasture sites. Agricultural land type present in a site and vegetation type affected functional diversity, with both agricultural land types showing a lower number of functionally distinct species than forests. We found papaya plantation sites showed species more evenly dispersed in trait space, suggesting they do better at conserving functional diversity when compared to cattle pasture sites. We demonstrate that sites that harbor agricultural activities can maintain a considerable proportion of the expected bat diversity. We note that this region still has large tracts of intact forest adjacent to agricultural lands, which may explain their ability to maintain relatively high levels bat diversity.
Heart Rate Monitor Instead of Ablation? Atrioventricular Nodal Re-Entrant Tachycardia in a Leisure-Time Triathlete: 6-Year Follow-Up
Authors: Gajda Robert
Published: June 2020

This study describes a triathlete with effort-provoked atrioventricular nodal re-entrant tachycardia (AVNRT), diagnosed six years ago, who ineffectively controlled his training load via heart-rate monitors (HRM) to avoid tachyarrhythmia. Of the 1800 workouts recorded for 6 years on HRMs, we found 45 tachyarrhythmias, which forced the athlete to stop exercising. In three of them, AVNRT was simultaneously confirmed by a Holter electrocardiogram (ECG). Tachyarrhythmias occurred in different phases (after the 2nd–131st minutes, median: 29th minute) and frequencies (3–8, average: 6.5 times/year), characterized by different heart rates (HR) (150–227 beats per minute (bpm), median: 187 bpm) and duration (10–186, median: 40 s). Tachyarrhythmia appeared both unexpectedly in the initial stages of training as well as quite predictably during prolonged submaximal exercise—but without rigid rules. Tachyarrhythmias during cycling were more intensive (200 vs. 162 bpm, p = 0.0004) and occurred later (41 vs. 10 min, p = 0.0007) than those during running (only one noticed but not recorded during swimming). We noticed a tendency (p = 0.1748) towards the decreasing duration time of tachycardias (2014–2015: 60 s; 2016–2017: 50 s; 2018–later: 37 s). The amateur athlete tolerated the tachycardic episodes quite well and the ECG test and echocardiography were normal. In the studied case, the HRM was a useful diagnostic tool for detecting symptomatic arrhythmia; however, no change in the amount, phase of training, speed, or duration of exercise-stimulated tachyarrhythmia was observed.
Entropy Derived from Causality
Authors: Riek Roland
Published: June 2020

The second law of thermodynamics, with its positive change of entropy for a system not in equilibrium, defines an arrow of time. Interestingly, also, causality, which is the connection between a cause and an effect, requests a direction of time by definition. It is noted that no other standard physical theories show this property. It is the attempt of this work to connect causality with entropy, which is possible by defining time as the metric of causality. Under this consideration that time appears only through a cause–effect relationship (“measured”, typically, in an apparatus called clock), it is demonstrated that time must be discrete in nature and cannot be continuous as assumed in all standard theories of physics including general and special relativity, and classical physics. The following lines of reasoning include: (i) (mechanical) causality requests that the cause must precede its effect (i.e., antecedence) requesting a discrete time interval >0. (ii) An infinitely small time step d t > 0 is thereby not sufficient to distinguish between cause and effect as a mathematical relationship between the two (i.e., Poisson bracket) will commute at a time interval d t , while not evidently within discrete time steps Δ t . As a consequence of a discrete time, entropy emerges (Riek, 2014) connecting causality and entropy to each other.
Medicinal and Aromatic Lamiaceae Plants in Greece: Linking Diversity and Distribution Patterns with Ecosystem Services
Authors: Cheminal Alexian , Kokkoris Ioannis P. , Strid Arne , Dimopoulos Panayotis
Published: June 2020

Research Highlights: This is the first review of existing knowledge on the Lamiaceae taxa of Greece, considering their distribution patterns and their linkage to the ecosystem services they may provide. Background and Objectives: While nature-based solutions are sought in many fields, the Lamiaceae family is well-known as an important ecosystem services provider. In Greece, this family counts 111 endemic taxa and the aim of the present study is to summarize their known occurrences, properties and chemical composition and analyze the correlations between these characteristics. Materials and Methods: After reviewing all available literature on the studied taxa, statistical and GIS spatial analyses were conducted. Results: The known properties of the endemic Lamiaceae taxa refer mostly to medicinal and antimicrobial ones, but also concern nutritional and environmental aspects. Essential oils compositions with high concentrations in molecules of interest (e.g., carvacrol, caryphyllene oxide, etc.) have been found in some taxa, suggesting unexploited applications for these taxa. Distribution patterns show a higher concentration of endemic Lamiaceae on the island of Kriti and southern Peloponnisos; patterns of the endemics’ properties are also highlighted in the biodiversity hotspot of Kriti. However, the lack of data for two thirds of the taxa, regarding their properties or specific distribution, shows a gap of knowledge. Results on endemic Lamiaceae properties and composition are correlated with the supply or potential supply of ecosystem services and the relevant hotspots have been identified. Conclusions: The Greek endemic Lamiaceae taxa are proved to be of great importance, regarding their chemical composition and the properties they confer. The distribution analysis suggests the existence of clustering patterns of plant species with common properties. Finally, this study highlights knowledge gaps that should be filled in order to ensure the conservation of the endemic Lamiaceae taxa and the preservation of the ecosystem services they provide or could potentially provide.
Quality Control of Thermally Modified Timber Using Dynamic Vapor Sorption (DVS) Analysis
Authors: Humar Miha , Repič Rožle , Kržišnik Davor , Lesar Boštjan , Cerc Korošec Romana , Brischke Christian , Emmerich Lukas , Rep Gregor
Published: June 2020

The importance of thermal modification is increasing worldwide. Increased use of thermally modified timber (TMT) has resulted in a need for reliable quality control, comprising control of variation of the production within defined limits, allowing third-party control in the case of certification and the regulation of customer complaints and claims. Techniques are thus needed to characterise the modification of quality in terms of improved target properties of TMT during industrial production, and of TMT products that have been in service for an arbitrary time. In this study, we aimed to utilise dynamic vapor sorption (DVS) for this purpose. Norway spruce (Picea abies) and European beech (Fagus sylvatica) samples were thermally modified at different temperatures according to different heat treatment techniques: (1) the Silvapro process based on an initial vacuum; (2) an air heat treatment, whereby samples were wrapped in aluminium foil; (3) thermal modification of wood samples in the ambient atmosphere in a laboratory oven. Wood samples from closed processes were analysed for validation. TMT was characterised with respect to mass loss, colour and density. Mass loss of wood due to modification (MLTM) was correlated with factors derived from DVS analysis. The present DVS measurements suggest that the equilibrium wood moisture content (EMC95% RH), the time to reach 10% wood moisture content (t10% MC), and the elongation factor, c, derived from a logarithmic function, can serve as alternative parameters to characterise the quality of several thermal modification processes. Further studies are recommended using other wood species, different modification processes and further parameters gained from DVS measurements to understand the robustness and the predictive power of the applied technique.
Influence of Copper and Biopolymer/Saqez Resin on the Properties of Poplar Wood
Authors: Dong Huijun , Bahmani Mohsen , Rahimi Sohrab , Humar Miha
Published: June 2020

There is an increasing trend in the use of environmentally-friendly materials in wood protection. This includes the use of less toxic active ingredients, as well as better fixation. This study investigates the formulation based on the combination of copper and Saqez resin on the physical and biological resistance properties of poplar wood. Samples were treated by either copper-ethanolamine (Cu/MEA) and/or Saqez resin at various treatment levels. A vacuum pressure procedure was applied. The retention, weight percent gain, water absorption, volumetric swelling, and decay resistance of the samples were then determined. The highest retention and weight percent gain were obtained in the samples treated with the combination of copper-based system and Saqez resin. Additionally, the combination of the copper and Saqez improved the physical properties and decay-resistance against white-rot fungus Trametes versicolor.
Effect of Natural Drying Methods on Moisture Content and Mass Change of Scots Pine Roundwood
Authors: Tomczak Karol , Tomczak Arkadiusz , Jelonek Tomasz
Published: June 2020

This study evaluated changes in mass and the moisture content of stored summer-harvested Scots pine small diameter roundwood subject to different types of preparation and storage (drying methods). Small diameter roundwood was naturally dried for three months, from 15 June to 15 September 2018. We analyzed three methods of preparation and storage. First, logs 1.2 m in length were stored and air-dried in piles (C). In the second case, a transpirational drying method was used (W). Thirdly and finally, we used air-drying for logs with lengths between 9.6 and 14.4 m (L) stored in the harvesting area. Within three months, the moisture content of the logs stored in piles decreased by 22.9 percentage points. With the transpirational drying method (W) the decrease in moisture content was 10.0 percentage points. In scenario L, at the end of the storage period the moisture content was lower by 15 percentage points. Within three months, the density of the roundwood stored in piles decreased to 700 kg/m3, which is about 140 kg/m3 more than in scenarios W and L. Cutting stemwood into short segments and storing it in a pile appears to have positive effects on drying performance. Overall, this study shows that, for Scots pine wood, air-drying is a better method than transpirational drying.
Observed and Potential Impacts of the COVID-19 Pandemic on the Environment
Authors: Cheval Sorin , Mihai Adamescu Cristian , Georgiadis Teodoro , Herrnegger Mathew , Piticar Adrian , Legates David R.
Published: June 2020

Various environmental factors influence the outbreak and spread of epidemic or even pandemic events which, in turn, may cause feedbacks on the environment. The novel coronavirus disease (COVID-19) was declared a pandemic on 13 March 2020 and its rapid onset, spatial extent and complex consequences make it a once-in-a-century global disaster. Most countries responded by social distancing measures and severely diminished economic and other activities. Consequently, by the end of April 2020, the COVID-19 pandemic has led to numerous environmental impacts, both positive such as enhanced air and water quality in urban areas, and negative, such as shoreline pollution due to the disposal of sanitary consumables. This study presents an early overview of the observed and potential impacts of the COVID-19 on the environment. We argue that the effects of COVID-19 are determined mainly by anthropogenic factors which are becoming obvious as human activity diminishes across the planet, and the impacts on cities and public health will be continued in the coming years.
Exercising in Times of Lockdown: An Analysis of the Impact of COVID-19 on Levels and Patterns of Exercise among Adults in Belgium
Authors: Constandt Bram , Thibaut Erik , De Bosscher Veerle , Scheerder Jeroen , Ricour Margot , Willem Annick
Published: June 2020

Countries all over the world implemented lockdowns to counteract COVID-19. These lockdowns heavily limited people’s exercise possibilities. At the same time, experts advocated to remain physically active to prevent future health problems. Based on an online survey, this study examines adults’ exercise levels and patterns during the COVID-19 lockdown in Belgium. Ordinal logistic regression analyses of 13,515 valid and population-weighted responses indicate a general increase in exercise frequencies, as well as in sedentary behavior. Except for people aged 55+, previously low active adults self-reported to exercise more during the lockdown. Among the people who were already high active before COVID-19, those above 55 years old, those with low education, those used to exercise with friends or in a sport club, and those who were not using online tools to exercise, self-reported to exercise less during the lockdown. Having less time, sitting more, and missing the familiar way and competitive element of exercising were the main reasons for a self-reported exercise reduction. Given the health risks associated with physical inactivity, results imply that governments should consider how those who were not reached can be encouraged to exercise during a lockdown. After all, additional COVID-19 lockdowns might be implemented in the future.
“In the past, the seeds I planted often didn’t grow.” A Mixed-Methods Feasibility Assessment of Integrating Agriculture and Nutrition Behaviour Change Interventions with Cash Transfers in Rural Bangladesh
Authors: Alam Ashraful , Khatun Wajiha , Khanam Mansura , Ara Gulshan , Bokshi Anowarul , Li Mu , Dibley Michael J.
Published: June 2020

Combining agriculture with behaviour change communication and other nutrition-sensitive interventions could improve feeding practices to reduce maternal and child undernutrition. Such integrated intervention requires rigorous design and an appropriate implementation strategy to generate an impact. We assessed feasibility and acceptability of an intervention package that combines nutrition counselling, counselling and support for home-gardening, and unconditional cash transfers delivered to women on a mobile platform for improving maternal and child nutrition behaviours among low-income families in rural Bangladesh. We used mixed-methods including in-depth interviews with women (20), key-informant interviews with project workers (6), and a cross sectional survey of women (60). Women well-accepted the intervention and reported to be benefited by acquiring new skills and information on home gardening and nutrition. They established homestead gardens of seasonal vegetables successfully and were able to find a solution for major challenges. All women received the cash transfer. Ninety-one percent of women spent the cash for buying foods, 20% spent it on purchasing seeds or fertilizers and 57% used it for medical and livelihood purchases. Project staff and mobile banking agent reported no difficulty in cash transfer. Combining nutrition-specific and -sensitive interventions is a feasible and acceptable approach. Using mobile technologies can provide additional benefits for the intervention to reach the disadvantage families in rural settings.
Food Co-Operatives: A Potential Community-Based Strategy to Improve Fruit and Vegetable Intake in Australia
Authors: Mihrshahi Seema , Partridge Stephanie R. , Zheng Xiaolei , Ramachandran Divya , Chia Debbie , Boylan Sinead , Chau Josephine Y.
Published: June 2020

Only 5% of Australian children and adults eat enough fruit and vegetables. Two common barriers are high cost and limited access. Food co-operatives (‘co-ops’) may have the potential to reduce these barriers. We conducted a scoping analysis of food co-ops in the Sydney region to describe their characteristics and objectives. We also conducted a survey of members and non-members of co-ops to assess their fruit and vegetable intake using validated questions. Fifteen food co-ops were identified in the Sydney region and the most common objective was to provide cheap affordable produce. Most co-ops (61%) were in areas of high socio-economic status (SES). Members of food co-ops had a higher vegetable intake than non-members [mean difference (MD) = 0.54 serves/daily; 95% confidence interval (CI) of 0.15 to 0.93] and were also more likely to meet the recommendations for fruit and vegetable intake [odds ratio (OR) = 4.77 (95% CI = 1.15, 19.86)]. Implications of this study are that if food co-ops can be implemented on a wider scale, they hold potential for improving fruit and vegetable intakes.
Adaptation and Validation of the Scale of Types of Users in Gamification with the Spanish Adolescent Population
Authors: Manzano-León Ana , Camacho-Lazarraga Pablo , Guerrero-Puerta Miguel A. , Guerrero-Puerta Laura , Alias Antonio , Trigueros Rubén , Aguilar-Parra José M.
Published: June 2020

The video game has been one of the phenomena with the greatest impact on the entire social fabric, and especially among young people. Therefore, it is essential to understand the interaction between the players and the video game itself. However, few instruments have been designed to assess the types of players in the adolescent population. Therefore, the purpose of this study was to validate the Gamification User Types Hexad Scale for the Spanish adolescent population. The sample of participants consisted of 1345 adolescents between the ages of 13 and 18. To evaluate the psychometric properties of the scale, a confirmatory factor analysis and a multi-group analysis of invariance by sex were performed. The results provide evidence of a valid and reliable six-factor instrument to measure the types of players in the Spanish adolescent population, regardless of their sex.
Nigella sativa and Its Active Compound, Thymoquinone, Accelerate Wound Healing in an In Vivo Animal Model: A Comprehensive Review
Authors: Sallehuddin Nusaibah , Nordin Abid , Bt Hj Idrus Ruszymah , Fauzi Mh Busra
Published: June 2020

Nigella sativa (NS) has been reported to have a therapeutic effect towards skin wound healing via its anti-inflammatory, tissue growth stimulation, and antioxidative properties. This review examines all the available studies on the association of Nigella sativa (NS) and skin wound healing. The search was performed in Medline via EBSCOhost and Scopus databases to retrieve the related papers released between 1970 and March 2020. The principal inclusion criteria were original article issued in English that stated wound healing criteria of in vivo skin model with topically applied NS. The search discovered 10 related articles that fulfilled the required inclusion criteria. Studies included comprise different types of wounds, namely excisional, burn, and diabetic wounds. Seven studies unravelled positive results associated with NS on skin wound healing. Thymoquinone has anti-inflammatory, antioxidant, and antibacterial properties, which mainly contributed to wound healing process.
Effect of Height of Fall on Mortality in Patients with Fall Accidents: A Retrospective Cross-Sectional Study
Authors: Hsieh Ting-Min , Tsai Ching-Hua , Liu Hang-Tsung , Huang Chun-Ying , Chou Sheng-En , Su Wei-Ti , Hsu Shiun-Yuan , Hsieh Ching-Hua
Published: June 2020

Background: Accidental falls are a common cause of injury and deaths. Both ground-level falls (GLF) and non-GLF may lead to significant morbidity or mortality. This study aimed to explore the relationship between height of falls and mortality. Method: This is a retrospective study based on the data from a registered trauma database and included 8699 adult patients who were hospitalized between 1 January 2009 and 31 December 2017 for the treatment of fall-related injuries. Study subjects were divided into three groups of two categories based on the height of fall: GLF (group I: < 1 m) and non-GLF (group II: 1–6 m and group III: > 6 m). The primary outcome was in-hospital mortality. The adjusted odds ratio (AOR) of mortality adjusted for age, sex, and comorbidities with or without an injury severity score (ISS) was calculated using multiple logistic regression. Results: Among the 7001 patients in group I, 1588 in group II, and 110 in group III, patients in the GLF group were older, predominantly female, had less intentional injuries, and had more pre-existing comorbidities than those in the non-GLF group. The patients in the non-GLF group had a significantly lower Glasgow Coma Scale (GCS), a higher injury severity score (ISS), worse physiological responses, and required more procedures performed in the emergency department. The mortality rate for the patients in group I, II, and III were 2.5%, 3.5%, and 5.5%, respectively. After adjustment by age, sex, and comorbidities, group II and group III patients had significantly higher adjusted odds of mortality than group I patients (AOR 2.2, 95% CI 1.64–2.89, p < 0.001 and AOR 2.5, 95% CI 1.84–3.38, p < 0.001, respectively). With additional adjustment by ISS, group II did not have significantly higher adjusted odds of mortality than group I patients (AOR 1.4, 95% CI 0.95–2.22, p = 0.082), but group III patients still had significantly higher adjusted odds of mortality than group I patients (AOR 10.0, 95% CI 2.22–33.33, p = 0.002). Conclusion: This study suggested that patients who sustained GLF and non-GLF were distinct groups of patients, and the height of fall did have an impact on mortality in patients of fall accidents. A significantly higher adjusted odds of mortality was found in the GLF group than in the non-GLF group after adjusting for age, sex, and comorbidities.
Application of Functional Data Analysis to Identify Patterns of Malaria Incidence, to Guide Targeted Control Strategies
Authors: Dieng Sokhna , Michel Pierre , Guindo Abdoulaye , Sallah Kankoe , Ba El-Hadj , Cissé Badara , Carrieri Maria Patrizia , Sokhna Cheikh , Milligan Paul , Gaudart Jean
Published: June 2020

We introduce an approach based on functional data analysis to identify patterns of malaria incidence to guide effective targeting of malaria control in a seasonal transmission area. Using functional data method, a smooth function (functional data or curve) was fitted from the time series of observed malaria incidence for each of 575 villages in west-central Senegal from 2008 to 2012. These 575 smooth functions were classified using hierarchical clustering (Ward’s method), and several different dissimilarity measures. Validity indices were used to determine the number of distinct temporal patterns of malaria incidence. Epidemiological indicators characterizing the resulting malaria incidence patterns were determined from the velocity and acceleration of their incidences over time. We identified three distinct patterns of malaria incidence: high-, intermediate-, and low-incidence patterns in respectively 2% (12/575), 17% (97/575), and 81% (466/575) of villages. Epidemiological indicators characterizing the fluctuations in malaria incidence showed that seasonal outbreaks started later, and ended earlier, in the low-incidence pattern. Functional data analysis can be used to identify patterns of malaria incidence, by considering their temporal dynamics. Epidemiological indicators derived from their velocities and accelerations, may guide to target control measures according to patterns.
The Advertising Policies of Major Social Media Platforms Overlook the Imperative to Restrict the Exposure of Children and Adolescents to the Promotion of Unhealthy Foods and Beverages
Authors: Sacks Gary , Looi Evelyn Suk Yi
Published: June 2020

There have been global calls to action to protect children (aged <18) from exposure to the marketing of unhealthy foods and beverages (‘unhealthy foods’). In this context, the rising popularity of social media, particularly amongst adolescents, represents an important focus area. This study aimed to examine the advertising policies of major global social media platforms related to the advertising of unhealthy foods, and to identify opportunities for social media platforms to take action. We conducted a desk-based review of the advertising policies of the 16 largest social media platforms globally. We examined their publicly available advertising policies related to food and obesity, as well as in relation to other areas impacting public health. The advertising policies for 12 of the selected social media platforms were located. None of these platforms adopted comprehensive restrictions on the advertising of unhealthy foods, with only two platforms having relevant (but very limited) policies in the area. In comparison, 11 of the 12 social media platforms had policies restricting the advertising of alcohol, tobacco, gambling, and/or weight loss. There is, therefore, an opportunity for major social media platforms to voluntarily restrict the exposure of children to the marketing of unhealthy foods, which can contribute to efforts to improve populations’ diets.
Comparison between Communicated and Calculated Exposure Estimates Obtained through Three Modeling Tools
Authors: Spinazzè Andrea , Borghi Francesca , Magni Daniele , Rovida Costanza , Locatelli Monica , Cattaneo Andrea , Cavallo Domenico Maria
Published: June 2020

This study aims to evaluate the risk assessment approach of the REACH legislation in industrial chemical departments with a focus on the use of three models to calculate exposures, and discuss those factors that can determine a bias between the estimated exposure (and therefore the expected risk) in the extended safety data sheets (e-SDS) and the expected exposure for the actual scenario. To purse this goal, the exposure estimates and risk characterization ratios (RCRs) of registered exposure scenarios (ES; “communicated exposure” and “communicated RCR”) were compared with the exposure estimates and the corresponding RCRs calculated for the actual, observed ES, using recommended tools for the evaluation of exposure assessment and in particular the following tools: (i) the European Centre for Ecotoxicology and Toxicology of Chemicals Targeted Risk Assessment v.3.1 (ECETOC TRA), (ii) STOFFENMANAGER® v.8.0 and (iii) the Advanced REACH Tool (ART). We evaluated 49 scenarios in three companies handling chemicals. Risk characterization ratios (RCRs) were calculated by dividing estimated exposures by derived no-effect levels (DNELs). Although the calculated exposure and RCRs generally were lower than communicated, the correlation between communicated and calculated exposures and RCRs was generally poor, indicating that the generic registered scenarios do not reflect actual working, exposure and risk conditions. Further, some observed scenarios resulted in calculated exposure values and RCR higher than those communicated through chemicals’ e-SDSs; thus ‘false safe’ scenarios (calculated RCRs > 1) were also observed. Overall, the obtained evidences contribute to doubt about whether the risk assessment should be performed using generic (communicated by suppliers) ES with insufficient detail of the specific scenario at all companies. Contrariwise, evidences suggested that it would be safer for downstream users to perform scenario-specific evaluations, by means of proper scaling approach, to achieve more representative estimates of chemical risk.
Effect of Wall Texture on Perceptual Spaciousness of Indoor Space
Authors: Wang Chong , Lu Wei , Ohno Ryuzo , Gu Zongchao
Published: June 2020

As the main place of people’s daily activities, indoor space (its size, shape, colors, material and textures, and so on) has important physical, emotional and health-based implications on people’s behavior and quality of life. Material texture is an integral part of architectural environment perception and quality evaluation, but the effect of material texture on perceptual spaciousness lacks the support of experimental data. This research examined the effects between different wall textures on the observer’s perception of spaciousness in indoor space, the influence of wall texture changes in different room sizes, and how the associational meaning of texture affects the degree of influence of wall texture on the spaciousness of indoor space. By using VR technology and the magnitude estimation (ME) analysis method, the authors found that the effect of wall texture on perceptual spaciousness varies depending on the wall material, and the textural effect is affected by room size. The perception of spaciousness is influenced by the observer’s associational meaning of material texture, and the influence of associational meaning of material texture varies contingent on the room size. In relatively small rooms, the objective aspect (such as hardness, surface reflectivity, texture direction and texture depth) of the wall texture has a significant impact on perceived space. In contrast, the effects of subjective aspects (such as affinity and ecology) become more pronounced in relatively larger rooms. This research makes up for the lack of material texture research in perceptual spaciousness, and provides a new way for the designer to choose materials for the design of a spatial scale.
A WHO Pathfinder Survey of Dental Caries in 6 and 12-Year Old Transylvanian Children and the Possible Correlation with Their Family Background, Oral-Health Behavior, and the Intake of Sweets
Authors: Ondine Lucaciu Patricia , Mester Alexandru , Constantin Ioana , Orban Nora , Cosma Lavinia , Candrea Sebastian , Sava-Rosianu Ruxandra , Mesaros Anca Stefania
Published: June 2020

To our knowledge, recent oral health data in Romania is poor, as no comprehensive oral health surveys have been carried out in the last five years. The present cross-sectional oral health survey aimed to assess the dental health status in 6 and 12-year old children from Transylvania, in correlation with their family background, oral-health behavior, and the intake of sweets. The study was conducted on 290 children from nine schools in the Transylvanian region of Romania. The study consisted of the clinical examination of children, recording of data in an International Cavity Detection and Assessment System (ICDAS) chart, and a questionnaire referring to the child’s parental education, frequency, and motivation of visits to the dentist, dental care habits, and the intake of sweets. Our results indicated that the most prevalent ICDAS scores recorded in 6-year-old children were “0A” (p = 0.001464), “03” (p = 0.00366), “05” (p = 0.005563), “06” for rural areas. Restorations were statistically more prevalent in the urban population (p = 0.000076). The ICDAS score for 12-year old children was “03” (p = 0.003614) and prevalent in the urban area. The ICDAS score for the rural area was “04” (p = 0.0056). Comparing dental health status with family background demonstrated a strong correlation for the group of 6-year-old children, and a lack of correlation for the 12-year-old children. The number of dental visits corelated with the parents’ backgrounds, and was higher in the urban population. Frequent hygiene habits (toothbrushing) were statistically correlated with lower ICDAS scores: “04” (p = 0.016482), “05” (p = 0.039127), “06” (p = 0.010785). Eating habits in both age groups were associated with statistically significant differences of “03”, “04”, “05”, “06”, “0A” in the ICDAS score. The obtained results provided clarification on the dental health situation in Romania and the potential risk factors of caries among the population, and therefore it could be used as a starter point for future studies to investigate, in depth, the effects of various variables on cavities found in Transylvanian schoolchildren.
Sedentary Behavior and the Use of Wearable Technology: An Editorial
Authors: O’Keeffe Nathan , Scheid Jennifer L , West Sarah L
Published: June 2020

Globally, we continue to face a mounting issue of obesity combined with inactivity; sedentary behaviour is independently associated with poor health outcomes including disease and mortality. As such, exploring ways to try to reduce sedentary behaviour and decrease the risk of diseases is an important area of consideration. The role of wearable technology, such as fitness trackers, to encourage and subsequently increase physical activity is relatively well documented. These devices have been successful at encouraging populations to increase daily activity levels. While time being sedentary is often correlated with physical activity participation, this is not always the case. Therefore, it may be just as important to consider the activity an individual is not doing when evaluating health and well-being. This Editorial will summarize the importance of distinguishing between physical activity and sedentary behaviour. It will also discuss how wearable technology, in the form of fitness trackers, may be used to encourage someone to break up sedentary bouts more often. Finally, we will consider important future research directions.
How to Communicate Food Safety after Radiological Contamination: The Effectiveness of Numerical and Narrative News Messages
Authors: Wolf Hanna Valerie , Perko Tanja , Thijssen Peter
Published: June 2020

Food risk and the safety of foodstuffs in the aftermath of contamination are highly sensitive issues to communicate. Food risks receive extensive attention from the news media, which requires messages to be carefully drafted to minimize harm and avoid unnecessary boycotts. Once a food risk is deemed eliminated, communication efforts must rebuild trust among consumers. The latter is a particularly difficult task after radiological contamination. This study tests whether numerical messages, narrative messages, or messages combining both elements are more effective in persuading the public to consume foodstuffs from Fukushima, a region that continues to battle stigma since the nuclear accident in 2011. We employ a survey-embedded experiment on a sample of the general Belgian population (N = 1085), during which respondents are presented with a mock news article presenting either a (1) numerical, (2) narrative, or (3) a combined message and test their subsequent evaluation of the article. We find that the numerical message leads to significantly higher perceived credibility and message acceptance than both the combined and the narrative message. Furthermore, we find that attitudes towards nuclear energy have a strong independent effect on message acceptance and evaluation, with those respondents who report a more positive stance towards nuclear energy more readily accepting the message. Food risk and safety communication may thus benefit from adopting a more detached, numerical approach for sensitive issues.
Evaluating Temporal Approximation Methods Using Burglary Data
Authors: Oswald Lukas , Leitner Michael
Published: June 2020

Law enforcement is very interested in knowing when a crime has happened. Unfortunately, the occurrence time of a crime is often not exactly known. In such circumstances, estimating the most likely time that a crime has happened is crucial for spatio-temporal analysis. The main purpose of this research is to introduce two novel temporal approximation methods, termed retrospective temporal analysis (RTA) and extended retrospective temporal analysis (RTAext). Both methods are compared to six existing temporal approximation methods and subsequently evaluated in order to identify the method that can most accurately estimate the occurrence time of crimes. This research is conducted with 100,000+ burglary crimes from the city of Vienna, Austria provided by the Criminal Intelligence Service Austria, from 2009–2015. The RTA method assumes that crimes in the immediate past occur at very similar times as in the present and in the future. Historical crimes with accurately known time stamps can therefore be applied to estimate when crimes occur in the present/future. The RTAext method enhances one existing temporal approximation method, aoristicext, with probability values derived from historical crime data with accurately known time stamps. The results show that the RTA method performs superiorly to all other temporal approximation methods, including the novel RTAext method, in two out of the three crime types analyzed. Additionally, the RTAext method shows very good results that are similar to the best performing existing approximation methods.
A Map Is a Living Structure with the Recurring Notion of Far More Smalls than Larges
Authors: Jiang Bin , Slocum Terry
Published: June 2020

The Earth’s surface or any territory is a coherent whole or subwhole, in which the notion of “far more small things than large ones” recurs at different levels of scale ranging from the smallest of a couple of meters to the largest of the Earth’s surface or that of the territory. The coherent whole has the underlying character called wholeness or living structure, which is a physical phenomenon pervasively existing in our environment and can be defined mathematically under the new third view of space conceived and advocated by Christopher Alexander: space is neither lifeless nor neutral, but a living structure capable of being more alive or less alive. This paper argues that both the map and the territory are a living structure, and that it is the inherent hierarchy of “far more smalls than larges” that constitutes the foundation of maps and mapping. It is the underlying living structure of geographic space or geographic features that makes maps or mapping possible, i.e., larges to be retained, while smalls to be omitted in a recursive manner (Note: larges and smalls should be understood broadly and wisely, in terms of not only sizes, but also topological connectivity and semantic meaning). Thus, map making is largely an objective undertaking governed by the underlying living structure, and maps portray the truth of the living structure. Based on the notion of living structure, a map can be considered to be an iterative system, which means that the map is the map of the map of the map, and so on endlessly. The word endlessly means continuous map scales between two discrete ones, just as there are endless real numbers between 1 and 2. The iterated map system implies that each of the subsequent small-scale maps is a subset of the single large-scale map, not a simple subset but with various constraints to make all geographic features topologically correct.
Evaluation of Melanoma (SK-MEL-2) Cell Growth between Three-Dimensional (3D) and Two-Dimensional (2D) Cell Cultures with Fourier Transform Infrared (FTIR) Microspectroscopy
Authors: Srisongkram Tarapong , Weerapreeyakul Natthida , Thumanu Kanjana
Published: June 2020

Fourier transform infrared (FTIR) microspectroscopy was used to evaluate the growth of human melanoma cells (SK-MEL-2) in two-dimensional (2D) versus three-dimensional (3D) spheroid culture systems. FTIR microspectroscopy, coupled with multivariate analysis, could be used to monitor the variability of spheroid morphologies prepared from different cell densities. The characteristic shift in absorbance bands of the 2D cells were different from the spectra of cells from 3D spheroids. FTIR microspectroscopy can also be used to monitor cell death similar to fluorescence cell staining in 3D spheroids. A change in the secondary structure of protein was observed in cells from the 3D spheroid versus the 2D culture system. FTIR microspectroscopy can detect specific alterations in the biological components inside the spheroid, which cannot be detected using fluorescence cell death staining. In the cells from 3D spheroids, the respective lipid, DNA, and RNA region content represent specific markers directly proportional to the spheroid size and central area of necrotic cell death, which can be confirmed using unsupervised PCA and hierarchical cluster analysis. FTIR microspectroscopy could be used as an alternative tool for spheroid cell culture discrimination, and validation of the usual biochemical technique.
Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men
Authors: Fahlbusch Pia , Knebel Birgit , Hörbelt Tina , Barbosa David Monteiro , Nikolic Aleksandra , Jacob Sylvia , Al-Hasani Hadi , Van de Velde Frederique , Van Nieuwenhove Yves , Müller-Wieland Dirk , Lapauw Bruno , Ouwens D. Margriet , Kotzka Jorg
Published: June 2020

Fatty liver occurs from simple steatosis with accumulated hepatic lipids and hepatic insulin resistance to severe steatohepatitis, with aggravated lipid accumulation and systemic insulin resistance, but this progression is still poorly understood. Analyses of hepatic gene expression patterns from alb-SREBP-1c mice with moderate, or aP2-SREBP-1c mice with aggravated, hepatic lipid accumulation revealed IGFBP2 as key nodal molecule differing between moderate and aggravated fatty liver. Reduced IGFBP2 expression in aggravated fatty liver was paralleled with promoter hypermethylation, reduced hepatic IGFBP2 secretion and IGFBP2 circulating in plasma. Physiologically, the decrease of IGFBP2 was accompanied with reduced fatty acid oxidation and increased de novo lipogenesis potentially mediated by IGF1 in primary hepatocytes. Furthermore, methyltransferase and sirtuin activities were enhanced. In humans, IGFBP2 serum concentration was lower in obese men with non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) compared to non-obese controls, and liver fat reduction by weight-loss intervention correlated with an increase of IGFBP2 serum levels. In conclusion, hepatic IGFBP2 abundance correlates to its circulating level and is related to hepatic energy metabolism and de novo lipogenesis. This designates IGFBP2 as non-invasive biomarker for fatty liver disease progression and might further provide an additional variable for risk prediction for pathogenesis of fatty liver in diabetes subtype clusters.