bluuebunny/crossref_metadata_2025 huggingface dataset:
The Application of e-Mental Health in Response to COVID-19: Scoping Review and Bibliometric Analysis
Authors: Ellis Louise A , Meulenbroeks Isabelle , Churruca Kate , Pomare Chiara , Hatem Sarah , Harrison Reema , Zurynski Yvonne , Braithwaite Jeffrey
Published: October 2021

Background

The COVID-19 pandemic and its mitigation measures and impacts, such as shelter-in-place orders, social isolation, restrictions on freedoms, unemployment, financial insecurity, and disrupted routines, have led to declines in mental health worldwide and concomitant escalating demands for mental health services. Under the circumstances, electronic mental health (e-mental health) programs and services have rapidly become the “new normal.”

Objective

The aim of this study was to assess key characteristics and evidence gaps in the e-mental health literature published in relation to the COVID-19 pandemic via a scoping review and bibliometric analysis.

Methods

We conducted a search of four academic databases (ie, MEDLINE, Embase, PsycInfo, and CINAHL) for documents published from December 31, 2019, to March 31, 2021, using keywords for e-mental health and COVID-19. Article information was extracted that was relevant to the review objective, including journal, type of article, keywords, focus, and corresponding author. Information was synthesized by coding these attributes and was then summarized through descriptive statistics and narrative techniques. Article influence was examined from Altmetric and CiteScore data, and a network analysis was conducted on article keywords.

Results

A total of 356 publications were included in the review. Articles on e-mental health quickly thrived early in the pandemic, with most articles being nonempirical, chiefly commentaries or opinions (n=225, 63.2%). Empirical publications emerged later and became more frequent as the pandemic progressed. The United States contributed the most articles (n=160, 44.9%), though a notable number came from middle-income countries (n=59, 16.6%). Articles were spread across 165 journals and had above-average influence (ie, almost half of the articles were in the top 25% of output scores by Altmetric, and the average CiteScore across articles was 4.22). The network analysis of author-supplied keywords identified key topic areas, including specific mental disorders, eHealth modalities, issues and challenges, and populations of interest. These were further explored via full-text analysis. Applications of e-mental health during the pandemic overcame, or were influenced by, system, service, technology, provider, and patient factors.

Conclusions

COVID-19 has accelerated applications of e-mental health. Further research is needed to support the implementation of e-mental health across system and service infrastructures, alongside evidence of the relative effectiveness of e-mental health in comparison to traditional modes of care.
Investigating Unhealthy Alcohol Use As an Independent Risk Factor for Increased COVID-19 Disease Severity: Observational Cross-sectional Study
Authors: Bhalla Sameer , Sharma Brihat , Smith Dale , Boley Randy , McCluskey Connor , Ilyas Yousaf , Afshar Majid , Balk Robert , Karnik Niranjan , Keshavarzian Ali
Published: October 2021

Background

Unhealthy alcohol use (UAU) is known to disrupt pulmonary immune mechanisms and increase the risk of acute respiratory distress syndrome in patients with pneumonia; however, little is known about the effects of UAU on outcomes in patients with COVID-19 pneumonia. To our knowledge, this is the first observational cross-sectional study that aims to understand the effect of UAU on the severity of COVID-19.

Objective

We aim to determine if UAU is associated with more severe clinical presentation and worse health outcomes related to COVID-19 and if socioeconomic status, smoking, age, BMI, race/ethnicity, and pattern of alcohol use modify the risk.

Methods

In this observational cross-sectional study that took place between January 1, 2020, and December 31, 2020, we ran a digital machine learning classifier on the electronic health record of patients who tested positive for SARS-CoV-2 via nasopharyngeal swab or had two COVID-19 International Classification of Disease, 10th Revision (ICD-10) codes to identify patients with UAU. After controlling for age, sex, ethnicity, BMI, smoking status, insurance status, and presence of ICD-10 codes for cancer, cardiovascular disease, and diabetes, we then performed a multivariable regression to examine the relationship between UAU and COVID-19 severity as measured by hospital care level (ie, emergency department admission, emergency department admission with ventilator, or death). We used a predefined cutoff with optimal sensitivity and specificity on the digital classifier to compare disease severity in patients with and without UAU. Models were adjusted for age, sex, race/ethnicity, BMI, smoking status, and insurance status.

Results

Each incremental increase in the predicted probability from the digital alcohol classifier was associated with a greater odds risk for more severe COVID-19 disease (odds ratio 1.15, 95% CI 1.10-1.20). We found that patients in the unhealthy alcohol group had a greater odds risk to develop more severe disease (odds ratio 1.89, 95% CI 1.17-3.06), suggesting that UAU was associated with an 89% increase in the odds of being in a higher severity category.

Conclusions

In patients infected with SARS-CoV-2, UAU is an independent risk factor associated with greater disease severity and/or death.
Computer-Aided Diagnosis of Gastrointestinal Ulcer and Hemorrhage Using Wireless Capsule Endoscopy: Systematic Review and Diagnostic Test Accuracy Meta-analysis
Authors: Bang Chang Seok , Lee Jae Jun , Baik Gwang Ho
Published: October 2021

Background

Interpretation of capsule endoscopy images or movies is operator-dependent and time-consuming. As a result, computer-aided diagnosis (CAD) has been applied to enhance the efficacy and accuracy of the review process. Two previous meta-analyses reported the diagnostic performance of CAD models for gastrointestinal ulcers or hemorrhage in capsule endoscopy. However, insufficient systematic reviews have been conducted, which cannot determine the real diagnostic validity of CAD models.

Objective

To evaluate the diagnostic test accuracy of CAD models for gastrointestinal ulcers or hemorrhage using wireless capsule endoscopic images.

Methods

We conducted core databases searching for studies based on CAD models for the diagnosis of ulcers or hemorrhage using capsule endoscopy and presenting data on diagnostic performance. Systematic review and diagnostic test accuracy meta-analysis were performed.

Results

Overall, 39 studies were included. The pooled area under the curve, sensitivity, specificity, and diagnostic odds ratio of CAD models for the diagnosis of ulcers (or erosions) were .97 (95% confidence interval, .95–.98), .93 (.89–.95), .92 (.89–.94), and 138 (79–243), respectively. The pooled area under the curve, sensitivity, specificity, and diagnostic odds ratio of CAD models for the diagnosis of hemorrhage (or angioectasia) were .99 (.98–.99), .96 (.94–0.97), .97 (.95–.99), and 888 (343–2303), respectively. Subgroup analyses showed robust results. Meta-regression showed that published year, number of training images, and target disease (ulcers vs erosions, hemorrhage vs angioectasia) was found to be the source of heterogeneity. No publication bias was detected.

Conclusions

CAD models showed high performance for the optical diagnosis of gastrointestinal ulcer and hemorrhage in wireless capsule endoscopy.
The Comparative Study of Social Organizations and Hospital
Authors: K. U. Dr. Vinay.
Published: October 2021

Abstract: Hospital is a social organization and logical combination of the activities of a number of persons with different level of knowledge and skill for achieving a common goal of patient care through a hierarchy of authority and responsibility. Public and professional interest in health services has increased dramatically over the last two decades. Medical sociologists have been interested in the structure, organization, dynamics, and impact of health services for well over 50 years. Sociologists have been instrumental in highlighting the challenges associated with integrating care, as well as the inter‐ and intra‐organizational dynamics that are occurring within increasingly complex healthcare systems (Flood and Fennel 1995; Light 2004; Scott et al. 2000). Understanding these organizational changes is critical because they reflect fundamental shifts in the nature of medical work and the delivery of health services. Today’s complex health systems represent fundamentally new configurations of an increasingly broad array of professional expertise that is altering the long standing system of professional. In this, the health care system has been elaborately discussed focusing mainly on hospital system. Following are some of the points focusing on hospital as a social organization. Goffman described hospitals as “total institutions” (referring in particular to asylums for those with mental health problems, but also to hospitals more generally), in which people were isolated from society over a period of time and led life an in enclosed and formally administered way (Goffman, 1968). He argued that, as a result of this experience, people often formed new relationships and attachments dependent on these institutions (i.e. underwent a process of “institutionalization”) that could make re-integration into the community on discharge very difficult. Keywords: Social organization, Hospital, Medical sociologists, Goffman, system of professional, “institutionalization
THE «ALTERNATIVE» MEANS OF USAGE OF SCIENTIFIC INSTRUMENTS IN RUSSIA OF THE 18TH CENTURY
Authors:   Museum for anthropology and ethnography RAS (Russia), Lupanova Ye.M.
Published: October 2021

The 18th century was marked by the appearance of a great number of unusual objects in Russia. Besides military ships, wardrobes and beds, wigs and Holland-fashioned suites they were all kinds of scientific instruments – compasses, astrolabes, sundials, clocks, bisecting dividers, electrostatic machines etс. They were visible and tangible signs of western culture, processes of Russian modernization and westernization. And besides the obvious for us today means of usage they had some other ones. Many instruments were multi-faceted. As a rule they all were rear and expensive things, hand-made by individual order in just few or even the only exemplar. Not everyone could use them. So the instruments demonstrated the high level of education and the high social status of the possessor. The instruments were used for entertainment both at the court and for general public. This kind of court activities was an important tool of attracting attention and state investments to the scientific researches. Clocks, sundials and telescopes played diplomatic role as gifts both on the level of transnational communication and on the local one (the establishment of good relations between arriving expeditions and local authorities). At last local peasants preserved the strange objects possessed by alien-dressed men as a super-modern weapon of pillage.
Trapping Sets of Quantum LDPC Codes
Authors: Raveendran Nithin , Vasić Bane
Published: October 2021

Iterative decoders for finite length quantum low-density parity-check (QLDPC) codes are attractive because their hardware complexity scales only linearly with the number of physical qubits. However, they are impacted by short cycles, detrimental graphical configurations known as trapping sets (TSs) present in a code graph as well as symmetric degeneracy of errors. These factors significantly degrade the decoder decoding probability performance and cause so-called error floor. In this paper, we establish a systematic methodology by which one can identify and classify quantum trapping sets (QTSs) according to their topological structure and decoder used. The conventional definition of a TS from classical error correction is generalized to address the syndrome decoding scenario for QLDPC codes. We show that the knowledge of QTSs can be used to design better QLDPC codes and decoders. Frame error rate improvements of two orders of magnitude in the error floor regime are demonstrated for some practical finite-length QLDPC codes without requiring any post-processing.
Valle de la muerte: factores que dificultan el éxito de innovaciones tecnológicas
Authors: Jiménez-Medina Elizabeth , Yepes-Callejas René , Giraldo-Builes Jim , Rojas-Arenas Iván Dario
Published: October 2021

El término valle de la muerte es una metáfora utilizada para describir una etapa de vacío o cuello de botella que experimentan los proyectos de innovación tecnológica después de las fases de investigación y desarrollo, y antes del desarrollo de nuevos productos y su lanzamiento al mercado. El objetivo de este artículo fue estudiar los factores involucrados en el valle de la muerte con el fin de ayudar en la definición de estrategias para superar esta brecha y, de este modo, aumentar las probabilidades de éxito de la innovación. Para ello se realizó una exploración de algunos de ellos y de relaciones causales a partir de entrevistas, así como de la revisión de información secundaria de nueve intermediarios de innovación ubicados en Medellín (Colombia), encargados de gestionar el valle de la muerte para acelerar los proyectos de innovación tecnológica hasta las etapas previas a la explotación comercial. Entre los hallazgos más relevantes de la investigación se encontró que los intermediarios de innovación en empresas, universidades y programas de apoyo estaban de acuerdo en que los factores que más inciden en la aparición del valle de la muerte son la falta de competencias del talento humano/roles mal distribuidos, ceguera en las dimensiones y la debilidad en el trabajo en red. Finalmente, el estudio concluye que el análisis de los factores generadores del valle de la muerte requiere de una visión sistémica y compleja, de forma que se puedan tener en cuenta las distintas interacciones que se establecen entre ellos.
Reputación, satisfacción y vínculo afectivo en el marco de la tercerización laboral en Colombia
Authors: Contreras-Pacheco Orlando E.
Published: October 2021

El presente estudio se propuso indagar por la forma en que los trabajadores en condición de tercerización laboral conciben su nivel de satisfacción en su trabajo, y el grado en que dicha valoración puede ser afectada en función de su propia percepción de reputación sobre la empresa subcontratista (su empleador) y la empresa usuaria (su cliente), así como de su nivel de vinculación afectiva con respecto a cada una de ellas. Para ello se planteó un modelamiento de ecuaciones estructurales mediante mínimos cuadrados parciales, empleándose cuatro hipótesis correlacionales y dos hipótesis de mediación. De esta manera, se aplicó un instrumento transversal sobre una muestra de 138 trabajadores tercerizados, vinculados a una misma empresa subcontratista en Colombia. Los resultados obtenidos indican que la reputación de esta empresa parecería incidir ligeramente sobre la vinculación afectiva de los trabajadores con respecto a ella misma, más no sobre su propia satisfacción en el trabajo. Finalmente, se observa una fuerte incidencia de la reputación de la empresa usuaria sobre la vinculación afectiva de sus trabajadores, variable que a su vez ejerce un rol de mediación parcial dentro del vínculo existente entre la misma reputación (de la empresa usuaria) y la satisfacción de los trabajadores.
Coevolución entre revoluciones industriales y ciencias económicas y administrativas
Authors: Montoya-Restrepo Iván Alonso
Published: October 2021

La cuarta revolución industrial ha comenzado a gestarse y a traer nuevas tecnologías de la información y la comunicación, así como novedosas formas de relacionamientos complejos entre procesos y organizaciones, y hace parte de los procesos de profundización en el alcance y diferenciación de la división del trabajo que fue originalmente gestado en las revoluciones predecesoras. El texto alude brevemente a la relación entre revoluciones industriales y ciencias económicas y administrativas, y a importantes transformaciones en el desarrollo civilizatorio occidental en el capitalismo liberal. En su desarrollo, se mencionan aspectos de estos cambios y se especula sobre las implicaciones de la reciente industria 4.0.
A VARIÁVEL SEXO/GÊNERO EM ESTUDOS SOCIOLINGUÍSTICOS: UM PANORAMA DAS TRÊS ONDAS
Authors: Souza-Silva André Luiz , Lucena Rubens Marques de
Published: October 2021

O presente artigo tem o objetivo de apresentar e refletir sobre dados de três pesquisas sociolinguísticas de cunho variacionista já realizadas, com a finalidade de exemplificar os estudos e interesses das “três ondas” de investigação da Sociolinguística, uma vez que essa área envolve variadas abordagens e desenvolve pesquisas sob uma égide comum: língua e sociedade são inseparáveis. Dito isso, este trabalho é de natureza qualitativa e de caráter bibliográfico, apresentando os estudos de primeira onda como mais estatísticos e binários, os de segunda onda como etnográficos e os de terceira onda como estilísticos, desprendendo-se de padrões binários limítrofes. Essas considerações se fazem possíveis à luz das vozes de Labov (2008), Bagno (2007, 2017), Eckert & McConnell-Ginet (2010), Freitag (2015), entre outros.
UMA ANÁLISE DOS MECANISMOS DE CONCEPTUALIZAÇÃO DO VERBO “CAIR” EM DADOS MULTIMODAIS
Authors: Passos Hayat , Lisboa André , Graça Beatriz , Avelar Maíra
Published: October 2021

O objetivo deste trabalho é analisar seis ocorrências do verbo “cair” abrigadas no Distributed Little Red Hen Lab, uma biblioteca de dados multimodais, a fim de descrever diferentes Modos de Representação e Esquemas Imagéticos corporificados nos gestos. Para isso, do ponto de vista teórico, recorremos às noções de Esquema Verbal, Modelos Cognitivos Idealizados, Frames, Esquemas Imagéticos, Construal, subjetividade e intersubjetividade. Além dessas noções, também abordamos a inter-relação entre metáforas e gestos; e, posteriormente, discutimos a respeito dos Modos de Representação Gestual. Do ponto de vista metodológico, desenvolvemos nossas análises baseando-nos no Sistema Linguístico de Notação Gestual (LASG), proposto por Bressem e colaboradoras (2013) e nas Orientações para a Análise de Metáforas nos Gestos (MIG-G), propostas por Cienki (2017). Foram selecionadas para análise seis ocorrências do verbo “cair”, a partir do critério de categorização “mais metafóricas” ou “menos prototípicas”, sendo que cada ocorrência funcionou de forma distinta: elas apresentaram diferentes Modos de Representação: “Holding/Molding (Segurar/Moldar –3D)”, “Enacting (Encenar)” e “Drawing” (Desenhar) e diferentes referentes físicos retratados no gesto: delimitar barreiras, objeto e desenhar um gráfico. Além disso, três ocorrências instanciaram nos gestos o Esquema Imagético Trajetória, uma ocorrência  instanciou o Esquema Imagético objeto e a metáfora conceptual “ideias são objetos”, correlacionada verbalmente a uma expressão idiomática com sentido metafórico. Outras duas ocorrências instanciaram a metáfora orientacional less is down (“Menos é para baixo”) e o Esquema Imagético Trajetória.
O PROJETO ENUNCIATIVO DA PÁGINA INSTITUCIONAL DE UMA IGREJA INCLUSIVA
Authors: Giacomelli Karina , Soares da Cunha Eduardo
Published: October 2021

Neste trabalho, analisamos, do ponto de vista enunciativo, a página institucional da Igreja Cristã Contemporânea (ICC), que se insere no campo religioso conhecido como “igrejas inclusivas”. Essas entidades, de um modo geral, se propõem a não condenar as sexualidades não hegemônicas e a acolhê-las, e vêm chamando a atenção de pesquisadores brasileiros devido à significativa expansão no número de fiéis e congregações. Nos interessou, portanto, pensar de que forma uma dessas instituições atua no ciberespaço, realizando seu trabalho de divulgação e captação de novos adeptos por meio de um gênero discursivo que organiza esse projeto de dizer. Para isso, buscamos apoio nos pressupostos teóricos desenvolvidos pelo Círculo de Bakhtin e alguns de seus estudiosos. Nossa análise foi realizada a partir de uma proposta de Sobral (2009), em diálogo com Brait (cf., p. ex., BRAIT, 2006) sendo constituída das operações integradas de descrição, análise e interpretação do objeto de estudo. Os resultados obtidos mostraram que, ao mesmo tempo em que a instituição, que recorre a um entrelaçamento entre o discurso religioso e o discurso empresarial, apresenta-se como um novo espaço religioso para aqueles que se sentem excluídos de igrejas tradicionais também promove uma restrição de seu público-alvo.
Como Consumidores de Baixa Renda Estabelecem uma Relação entre o Autocontrole, a Consciência de Preço e o Consumo Sustentável?
Authors: Nascimento Helton , Salomé Ribeiro Costa Cristiane , Oliveira Damascena Elielson , Zimmerle da Nóbrega Costa Flávia
Published: October 2021

Como os produtos sustentáveis são geralmente mais caros, o senso coletivo entende que os consumidores de baixa renda estão menos aptos a praticarem o consumo sustentável. A literatura do marketing tem explorado pouco a questão, visto que esses consumidores tendem a tomar decisões de compra mais respaldadas por critérios de autocontrole financeiro e de consciência de preço. Contudo, estudos apontam que tais decisões, mesmo quando tomadas sem estar relacionadas à sustentabilidade, geram efetivamente um consumo sustentável. Assim, esse trabalho buscou compreender como os consumidores de baixa renda, em suas decisões de compra, relacionam o autocontrole das despesas, a consciência de preço com o consumo sustentável. Com um corpus formado por 18 entrevistas em profundidade e apoiados numa análise de discurso funcional, nossos resultados apontaram a existência de três relações efetuadas pelos consumidores: eles entendem que contribuem com a sustentabilidade por gerar um menor descarte do lixo e provocar uma menor extração da matéria-prima e, ainda, ao fazê-lo, acreditam despertar o desejo de adoção de práticas ambientais. Concluímos que, ao estabelecer tais relações, possamos gerar práticas de consumo mais reflexivas, portanto, mais responsáveis em relação aos impactos ambientais causados por decisões de consumo.
[ID 57067] IMPACTO DA PANDEMIA DE COVID-19 SOBRE A PRÁTICA DE EXERCÍCIOS FÍSICOS EM MULHERES
Authors: Saraiva Ferreira Joel , Campagna de Assis Tayla , Presotto Vicente Cruz Rafael , Dellagrana Rodolfo André
Published: October 2021

Objetivo: Avaliar o impacto da pandemia de COVID-19 sobre a prática de exercícios físicos em mulheres, durante o período de distanciamento social estabelecido pelo poder público municipal de Campo Grande/MS. Metodologia: Realizou-se um estudo transversal, com abordagem quantitativa e amostragem probabilística por conglomerado, considerando a proporção de mulheres com idade igual ou superior a 18 anos, residentes nas sete regiões urbanas do município. A coleta de dados ocorreu com uso de formulário online, distribuído por aplicativo de mensagem às mulheres cadastradas no programa de promoção de atividades físicas da Fundação Municipal de Esportes, no período de 7 a 14 de abril de 2020. Foram coletados dados sociodemográficos (idade e escolaridade) e quantidade semanal (minutos) de prática de exercícios físicos antes e durante o período de distanciamento social. Os dados foram analisados no programa SPSS versão 20.0, por meio de regressão logística e teste do qui-quadrado. O estudo foi realizado com aprovação do Comitê de Ética em Pesquisa com Seres Humanos da Universidade Federal de Mato Grosso do Sul. Resultados: Foram recebidos 1188 formulários com respostas válidas. Percebeu-se que o número de mulheres ativas fisicamente (≥ 150 minutos/semanais) passou de 51% para 10,6%, comparando o momento anterior e durante a pandemia de COVID-19 (p<0,05). O período de distanciamento social aumentou oito vezes a chance da população avaliada se tornar insuficientemente ativa fisicamente (p<0,05). Conclusão: Medidas de distanciamento social, destinadas à contenção da COVID-19, provocaram diminuição drástica na proporção de mulheres ativas fisicamente nesse período.
[ID 57202] CORRELAÇÃO ENTRE O ESTADO NUTRICIONAL E A FORÇA DE PREENSÃO PALMAR DE IDOSOS ATENDIDOS EM UM HOSPITAL UNIVERSITÁRIO
Authors: Alencar Duarte Heloísa , César Guimarães Freire Júlio , Brito Sampaio Karoliny , Maciel Barbosa Janine , Martiniano da Silva Luana , Clebeson de Oliveira Lucídio , Emilly da Silva Morais Letícia
Published: October 2021

Objetivo: Verificar a associação entre o estado nutricional e a força de preensão palmar em idosos atendidos no Ambulatório de Geriatria de um Hospital Universitário. Metodologia: Trata-se de um estudo quantitativo, do tipo exploratório e descritivo, com delineamento transversal. Para a coleta de dados foi utilizado um questionário semiestruturado composto por quatro módulos. Resultados: A amostra foi constituída por 100 idosos com idades entre 60 e 92 anos. Na amostra analisada, 78% eram do sexo feminino, 97% dos idosos entrevistados residiam na zona urbana e 65% destes eram analfabetos ou obtiveram poucos anos de estudo e mais da metade estava classificada na classe econômica C. Destes, 50% apresentaram sobrepeso/obesidade, sendo as mulheres aquelas que apresentaram maior prevalência dessa condição. Em relação à força de preensão palmar, os homens, em todas as faixas etárias, apresentaram maior valor médio de força quando comparados às mulheres e o maior valor de média de força foi observado na faixa etária de 70 a 74 anos de idade. Conclusão: Concluiu-se que a força de preensão palmar apresentava-se como uma medida de grande importância para a detecção precoce de desnutrição, fragilidade e sarcopenia em pessoas idosas.
Integrated multi-omics analysis uncovers roles of mdm-miR164b-MdORE1 in strigolactone mediated inhibition of adventitious root formation in apple
Authors: Fan Xingqiang , Li Hui , Guo Yushuang , Qi Qi , Jiang Xiangning , Wang Yi , Xu Xuefeng , Qiu Changpeng , Li Wei , Han Zhenhai
Published: October 2021

Adventitious root (AR) formation is important for the vegetative
propagation. The effects of strigolactones (SLs) on AR formation have
been rarely reported, especially in woody plants. In this study, we
first verified the inhibitory effects of SLs on AR formation in apple
materials. Transcriptome analysis identified 12,051 differentially
expressed genes over the course of AR formation, with functions related
to organogenesis, cell wall biogenesis or plant senescence. WGCNA
suggests SLs might inhibit AR formation through repressing the
expression of two core hub genes, MdLAC3 and MdORE1. We
further verified that enhanced cell wall formation and accelerated
senescence were involved in the AR inhibition caused by SLs. Combining
small RNA and degradome sequencing, as well as a dual-luciferase sensor
system, we identified and validated three negatively correlated
miRNA–mRNA pairs, including mdm-miR397–MdLAC3 involved in
secondary cell wall formation, and mdm-miR164a/b–MdORE1 involved
in senescence. Finally, we have experimentally demonstrated the role of
mdm-miR164b–MdORE1 in SLs-mediated inhibition of AR formation.
Overall, our findings not only propose a comprehensive regulatory
network for the function of SLs on AR formation, but also provide novel
candidate genes for the potential genetic improvement of AR formation in
woody plants using transgenic or CRISPR technology.
Erosive cheilitis as an early manifestation in DRESS syndrome
Authors: salha wahbi ben , moussaoui eya , oualha lamia , Anoun Jihed , Douki Nabiha
Published: October 2021

Drug reaction with eosinophilia and systemic symptoms (DRESS) is part of
Severe cutaneous adverse reactions. Allopurinol, an uric acid-lowering
drug, had been incriminated in several cases of Allopurinol-induced
Dress syndrome.Through this paper, we present a case of
Allopurinol-induced DRESS syndrome with initial oral mucosal
involvement.
Data augmentation techniques for transfer learning improvement in drill wear classification using convolutional neural network
Authors: Kurek Jarosław , Aleksiejuk-Gawron Joanna , Antoniuk Izabella , Górski Jarosław , Jegorowa Albina , Kruk Michał , Orłowski Arkadiusz , Pach Jakub , Świderski Bartosz , Wieczorek Grzegorz
Published: October 2021

This paper presents an improved method for recognizing the drill state on the basis of hole images drilled in a laminated chipboard, using convolutional neural network (CNN) and data augmentation techniques. Three classes were used to describe the drill state: red - for drill that is worn out and should be replaced, yellow - for state in which the system should send a warning to the operator, indicating that this element should be checked manually, and green - denoting the drill that is still in good condition, which allows for further use in the production process. The presented method combines the advantages of transfer learning and data augmentation methods to improve the accuracy of the received evaluations. In contrast to the classical deep learning methods, transfer learning requires much smaller training data sets to achieve acceptable results. At the same time, data augmentation customized for drill wear recognition makes it possible to expand the original dataset and to improve the overall accuracy. The experiments performed have confirmed the suitability of the presented approach to accurate class recognition in the given problem, even while using a small original dataset.
Classifiers ensemble of transfer learning for improved drill wear classification using convolutional neural network
Authors: Kurek Jarosław , Aleksiejuk-Gawron Joanna , Antoniuk Izabella , Górski Jarosław , Jegorowa Albina , Kruk Michał , Orłowski Arkadiusz , Pach Jakub , Świderski Bartosz , Wieczorek Grzegorz
Published: October 2021

In this paper we introduce the enhanced drill wear recognition method, based on classifiers ensemble, obtained using transfer learning and data augmentation methods. Red, green and yellow classes are used to describe the current drill state. The first one corresponds to the case when drill should be immediately replaced. The second one denotes a tool that is still in a good condition. The final class refers to the case when a drill is suspected of being worn out, and a human expert evaluation would be required. The proposed algorithm uses three different, pretrained network models and adjusts them to the drill wear classification problem. To ensure satisfactory results, each of the methods used was required to achieve accuracy above 90% for the given classification task. Final evaluation is achieved by voting of all three classifiers. Since the initial data set was small (242 instances), the data augmentation method was used to artificially increase the total number of drill hole images. The experiments performed confirmed that the presented approach can achieve high accuracy, even with such a limited set of training data.
Predictors of Response to Biologics in Patients with Moderate-to-severe Psoriasis: A Danish Nationwide Cohort Study
Authors: Schwarz Christopher Willy , Loft Nikolai , Rasmussen Mads Kirchheiner , Nissen Christoffer V. , Dam Tomas Norman , Ajgeiy Kawa Khaled , Egeberg Alexander , Skov Lone
Published: October 2021

Identifying patient characteristics associated withachieving treatment response to biologics in patients with psoriasis could prevent expensive switching between biologics. The aim of this study was to identifypatient characteristics that predict the efficacy of treatment for biologics that inhibit tumour necrosis factor-α, interleukin-12/-23, and -17A. The study investigated biologic-naïve patients from the DERMBIO registry treated with adalimumab, etanercept, infliximab, secukinumab, or ustekinumab. Multivariable logistic models were conducted to assess associations between patient characteristics and treatment response. A total of 2,384 patients were included (adalimumab n = 911; etanercept n = 327; infliximab n = 152; secukinumab n = 323; ustekinumab n = 671). Smoking (odds ratio 0.74; 95% confidence interval (CI) 0.56–0.97; p = 0.03) and higher bodyweight (odds ratio 0.989; 95% CI 0.984–0.994; p < 0.001) reduced the odds of achieving response defined as Psoriasis Area and Severity Index ≤2.0 after 6 months of treatment. In conclusion, higher bodyweight and smoking were associated with a reduced probability of treatment response for tumour necrosis factor-α inhibitors, ustekinumab, and secukinumab.
PRONÓSTICO DE DEMANDA DE ENERGÍA ELÉCTRICA USANDO PROCESOS GAUSSIANOS: UN ANÁLISIS COMPARATIVO
Authors: Loaiza Muñoz Jorge Eliecer , Zuluaga Carlos D.
Published: October 2021

Abstract—Load demand forecasting is an essential component for planning power systems, and it is an invaluable tool to grid operators or customers. Many methods have been proposed to provide reliable estimates of electric load demand, but few methods can address the problem of predicting energy demand from a probabilistic point of view. One of them is the Gaussian processes (GP) that considering an adequate covariance function are suitable tools to carry out this load forecasting task. In this article, we show how to use Gaussian processes to predict elec- trical energy demand. Additionally, we thoroughly test various covariance functions and provide a new one. The performance of the proposed methodology was tested on two real data sets, showing that GPs are competitive alternatives for short-term load demand forecasting compared to other state-of-the-art methods
Caracterización de la Dispensación y la Administración de un Anticonceptivo Inyectable Frente a la Normatividad Vigente en Colombia
Authors: Clavijo Cohen Germán , González Rozo Zareth Vanessa
Published: October 2021

Objetivo. Caracterizar las buenas prácticas de dispensación y administración del producto inyectable Cyclofem en los servicios farmacéuticos de baja complejidad (SFBC), en una localidad de Bogotá D.C.Métodos. Estudio descriptivo, en el cual se adecuó el instrumento de simulación de compra, presencial divulgado por Vacca, (2011, p.588); dicho instrumento se aplicó en los SFBC de una localidad de BOGOTA D.C. La muestra final correspondiócon 265 SFBC, con una confiabilidad del 95%.Resultados. Se encontró que el 88% de los SFBC dispensaban Cyclofem sin prescripción médica, y solo una (1) requirió la prescripción para la dispensación, del medicamento.Conclusiones. La normatividad colombiana exige que el personal a cargo de servicios farmacéuticos dispense y administre los anticonceptivos inyectables bajo prescripción médica, de acuerdo con los resultados del estudio, dicha exigencia no se acata en los SFBC de la ciudad de Bogotá D.C.
Bienestar psicológico en estudiantes de educación superior
Authors: Téllez Bedoya Carolina
Published: October 2021

El propósito del estudio fue desarrollar una revisión acerca del Bienestar Psicológico, especialmente en estudiantes universitarios. Para ello, se realizó una búsqueda sistemática de literatura adaptando la metodología planteada por Tranfield, Denyer y Smart (2003), propuesta en tres etapas, planeación de la revisión, desarrollo de la revisión (noventa y un estudios nacionales e internacionales) y reporte, iniciando desde el concepto de bienestar hasta la definición de bienestar psicológico desde una perspectiva multidimensional.

Así mismo, se presentan diversas estrategias para favorecer las condiciones académicas de los estudiantes en educación superior orientadas a la permanencia, incluye lineamientos futuros de investigación y limitaciones prácticas del estudio. Esto se visualiza a partir de una estructura multidimensional, en la cual se articula tanto el bienestar hedónicocomo el eudaimónico e incentiva el desarrollo de políticas que favorezcan la salud mental y física de la comunidad educativa, ya que el Bienestar Psicológico tiene tendencia a ser visualizado de esa forma.
Frecuencia de recién nacidos prematuros de comunidades indígenas con oxigenoterapia en un programa madre canguro
Authors: Carrillo Janeth , Cellamen Yuly , Flórez Daniela , Havith Jaime
Published: October 2021

Según la Organización Mundial de la Salud, OMS, un niño es prematuro cuando nace antes de haber completado 37 semanas de gestación. Cada año nacen cerca de 15 millones de niños prematuros en el mundo. En Colombia, el 10% de los bebés que nacen son prematuros y el 9% nacen con bajo peso. En un país pluriétnico como el nuestro, se requiere calcular la frecuencia de este evento en comunidades indígenas, que tienen barreras de acceso a servicios de salud especializados. Objetivo: Estimar la frecuencia de niños prematuros procedentes de comunidades indígenas, que requieran oxígeno, y que son atendidos en el Programa Madre Canguro de la Subred Integrada de Servicios de Salud Sur de Bogotá en el año 2018. Método: Se realizó una investigación de tipo cuantitativo, descriptivo transversal retrospectivo. Resultados: el 3% de los pacientes atendidos procedían de comunidades indígenas; el 60% de ellos fueron clasificados como muy prematuros y moderados o tardíos (entre 28 y 37 semanas de gestación). Conclusiones: si bien la frecuencia de prematuros en el programa madre canguro es baja, las condiciones culturales de la atención son particulares para este grupo étnico.
Igranie z ogniem – rytuały pogrzebowe kultury strzyżowskiej na przykładzie wybranych pochowków z cmentarzyska w Rogalinie
Authors: Hyrchała Anna
Published: October 2021

The text presents newly discovered graves of Strzyżów culture from the Early Bronze Age, located at a cemetery in Rogalin, Poland. The funeral rites of Strzyżów culture are multifaceted. Most of the dead were placed in graves in supine position, equipped with vessels, tools, and ornaments – and then buried. This text, however, discusses burial rites involving the use of fire both in open burial pits and after burial, as well as subsequent practices of opening and disturbing graves. Analysis was supplemented by results of radiocarbon dating.
Kamienie zrodzone z pioruna. O nietypowej formie recyklingu w średniowieczu i czasach nowożytnych
Authors: Kurasiński Tomasz
Published: October 2021

The article is an attempt to determine to what extent the folkloric and ethnographic data concerning the cultural significance and functions performed by re-used stone products hailing from prehistoric times (mainly various types of axes, hammers, adzes, and hammers axes, usually from the Neolithic, less often from other periods), are reflected in medieval and modern historical materials. Finds from almost all over Europe were taken into account. In the Middle Ages and later, thunderstones gained a great deal of importance, because there were few items that, after their original function had disappeared,remained in such wide use, far beyond traditionally understood recycling, which is usually limited to the re-use of raw materials and remedial actions. As objects of great sacred importance, they found a permanent place in the rituals and imaginations of ancient communities.
Multi-Population Ensemble Particle Swarm Optimizer based Energy Efficient Clustering Algorithms for IOT Applications
Authors: Adlak Roshnee , Meena Pooja
Published: October 2021

With the growth of wireless sensor networks (WSN), new technologies like the Internet-of-Things (IoT) are being created. There may be challenges that come because when implementing these application areas in practice. The primary issue is energy utilization while data transmission between these resource restricted sensors. In this work, we present a cluster-based routing protocol for IoT to anticipate energy utilization. Furthermore, for cluster head selection and cluster updation, we presented a multi-population ensemble particle swarm optimizer. The simulation was carried out using the MATLAB platform and demonstrates its superiority over different approaches.
Pathology of obstacles of implementation of national curriculum document of Iran from the perspective of curriculum professors
Authors: Shamaghdari Ehsan , Nourabadi Soolmaz
Published: October 2021

The aim of the present study is to identify the obstacles to the implementation of the National Curriculum Document of the Islamic Republic of Iran from the perspective of curriculum professors. 46 professors of public universities in Tehran were selected as the available statistical sample. The results of the study indicate that the average importance of obstacles to the implementation of this document is a significant difference between the sample average and the hypothetical average of the community at a significant level of 0.01 (t = 58.30). The results indicate that the importance of obstacles to the implementation of this document is moderate to high because the average obtained 3.72 is higher than the hypothetical average of number 3. Also the results of Friedman test show that from the perspective of respondents, the most important obstacle to the implementation of this document was the human obstacles, and the least important factor was structural obstacles. This relationship is also statistically confirmed because the significance level obtained is less than 0.05.
Resource - saving in the industrial sector of the region based on the model of systematic clustering synthesis
Authors: Tyukavkin Nikolay M. , Sedov Ivan A. , Krasilnikova Yulia S. , Sesorova Olga V. , Stepanov Roman A. , Prokhorova Olga V.
Published: October 2021

The purpose of the research is to develop a synthesis model of systematic clustering of the regional industrial complex and and propose an idea of creating cluster alliance based on networking and innovation ecosystem of the region, where clusters will have access to the required resource base, infrastructure and information services. The authors offer directions of a systematic clustering of integrated industrial complexes of the region, which are defined by the fact that the industrial clusters in the contemporary conditions, being “points of growth and regional development” are capable of improving innovative activity in terms of quality in constituent entities of the Russian Federation, by means of networking and systematic arrangement of cooperation between economic entities. The research materials can be useful for the Managers of industrial enterprises, Experts in the sphere of economics and management.
«mozos bonitos»
Authors: Ortiz Vergara Jorge Israel
Published: October 2021

La expresión «mozos bonitos» tuvo múltiples sentidos y circuló en periódicos brasileños en la primera mitad del siglo XX. Junto con otros sentidos, fue referencia para el afeminamiento, la homosexualidad, el travestismo, el transformismo y la prostitución masculina. En este trabajo, el autor registra la existencia de algunos varones que se identificaron e incorporaron nombres, indumentaria, maquillaje y actitudes de mujeres, prostitutas y artistas mujeres. Junto con la consideración de textos de especialistas en homosexualidad de la época, se comentan los usos de las voces «almohadilla» (almofadinha), «travesti» y «transformista».
El poder, el sujeto y la interpretación jurídica: un abordaje basado en el pensamiento tardío de Michel Foucault
Authors: Ortiz Juan Emilio
Published: October 2021

En sus últimas investigaciones, Michel Foucault propuso una ontología del presente, orientada a explorar el nudo constituido por tres ejes interrelacionados: el eje del saber, el eje del poder y el eje de la subjetividad. El presente trabajo pretende explorar las implicancias este método para pensar la interpretación jurídica. El argumento analizará el conjunto de relaciones que intervienen en la constitución misma de una subjetividad. El régimen de verdad imperante en una sociedad contribuye a la formación de prejuicios, preconceptos y naturalizaciones, que condicionan la interpretación que se hace tanto de la realidad como de la estructura normativa. Siguiendo esta línea, el presente escrito permitirá desarrollar un enfoque que considere las relaciones e implicancias múltiples entre ciertas verdades a las que adscribe un sujeto (el magistrado) y el modo en que se transmiten al dictado de sentencias (que son interpretaciones). Procuraré mostrar que esta vía permite operar en un espacio muy sutil constituido entre el derecho positivo y la praxis interpretativa de los Magistrados.  Entiendo que este análisis constituye una cuestión iusfilosófica de gran importancia cuyo tratamiento también le corresponde a la dogmática del derecho.
Hidrovía Paraná-Paraguay
Authors: Cieza Daniel
Published: October 2021

El trabajo propone un estudio crítico de la denominada hidrovía del Paraná-Paraguay, por la que sale la mayor parte de la producción del Mercosur. Plante una revisión de un tema de mucha actualidad en el que se debate la apropiación de los beneficios de las mercancías que circulan por la hidrovía, junto con la existencia de delitos vinculados al tráfico de mercancías legales e ilegales. Propone para solucionar estos flagelos el fortalecimiento de Fiscalías especializadas en delitos económicos vinculados al narcotráfico y a la evasión fiscal, así como el desarrollo de una inteligencia estratégica preventiva, son fundamentales. Concluye que es muy importante la coordinación de las Agencias fiscales del Mercosur a fin de detectar las “triangulaciones” de las grandes empresas granarias, y resulta imprescindible una política regional en defensa de los recursos naturales y contra el narcotráfico.
Breve esbozo de la evolución histórica de las garantías de los derechos fundamentales en Cuba
Authors: Alejo Martínez Carlos Alberto
Published: October 2021

El presente trabajo versa sobre las garantías de los derechos fundamentales frente al poder sancionador del Estado en el ordenamiento jurídico cubano, realizando un breve esbozo sobre su evolución histórica, con especial atención a lo preceptuado en este sentido en el orden constitucional, desde la etapa colonial hasta el momento de ruptura que constituye la consagración constitucional del debido proceso como garantía de los derechos fundamentales en la Constitución cubana de 2019, así como de las falencias que presenta en este sentido el proceso penal cubano y la necesidad de cambios legislativos a fin de que concuerden con el nuevo texto constitucional de acuerdo a los principios de legalidad, supremacía constitucional y jerarquía normativa a fin de lograr un modelo garantista frente al ius puniendi estatal.
Comparison of intraocular pressures estimated by rebound and applanation tonometry in dogs with lens instability: 66 cases (2012–2018)
Authors: Schlesener Brittany N. , Leonard Brian C. , Miller Paul E. , Kass Philip H. , Hollingsworth Steven R. , Cooper Ann E. , Maggs David J.
Published: October 2021

OBJECTIVE

To compare intraocular pressures (IOPs) estimated by rebound and applanation tonometry for dogs with lens instability.

ANIMALS

66 dogs.

PROCEDURES

Medical records of dogs examined between September 2012 and July 2018 were reviewed for diagnoses of anterior (ALL) or posterior (PLL) lens luxation or lens subluxation.

RESULTS

Estimates of IOP obtained with rebound and applanation tonometry significantly differed from each other for all types of lens instability considered collectively (mean ± SE difference between tonometric readings, 8.1 ± 1.3 mm Hg) and specific types of lens instability considered individually (mean ± SE difference between tonometric readings: ALL, 12.8 ± 2.5 mm Hg; PLL, 5.9 ± 1.7 mm Hg; subluxation, 2.8 ± 0.8 mm Hg). Median (range) differences between rebound and applanation tonometer readings for dogs with ALL was 5 mm Hg (–9 to 76 mm Hg), with PLL was 3 mm Hg (–1 to 19 mm Hg), and with lens subluxation was 3 mm Hg (–9 to 18 mm Hg). In eyes with ALL, rebound tonometer readings exceeded applanation tonometer readings on 44 of 60 (73%) occasions.

CONCLUSIONS AND CLINICAL RELEVANCE

Rebound tonometry yielded higher estimates of IOP than did applanation tonometry in eyes with ALL and with all types of lens luxation considered collectively. Estimates of IOP in eyes with lens instability should ideally be obtained with both rebound and applanation tonometers. Veterinarians with only one type of tonometer should interpret results for dogs with lens instability concurrent with physical examination findings.