bluuebunny/crossref_metadata_2025 huggingface dataset:
N-Acetylcysteine Attenuates Cisplatin Toxicity in the Cerebrum and Lung of Young Rats with Artificially Induced Protein Deficiency
Authors: Calderón Guzmán David , Osnaya Brizuela Norma , Ortíz Herrera Maribel , Valenzuela Peraza Armando , Labra Ruíz Norma , Juárez Olguín Hugo , Santamaria del Angel Daniel , Barragán Mejía Gerardo
Published: June 2024

Neurotoxicity is a major obstacle in the effectiveness of Cisplatin in cancer chemotherapy. In this process, oxidative stress and inflammation are considered to be the main mechanisms involved in brain and lung toxicity. The aim of the present work was to study the influence of the amount of protein on some oxidative parameters in the brain and lungs of rats treated with Cisplatin (CP) and N-Acetylcysteine (NAC) as neuroprotectors. Four groups of Wistar rats, each containing six animals, were fed with a protein diet at 7% for 15 days. Thereafter, the groups were given either a unique dose of CP® 5 mg/kg or NAC® 5 mg/kg as follows: group 1 (control), NaCl 0.9% vehicle; group 2, CP; group 3, NAC; and group 4, NAC + CP. The animals were sacrificed immediately after the treatments. Blood samples were collected upon sacrifice and used to measure blood triglycerides and glucose. The brain and lungs of each animal were obtained and used to assay lipid peroxidation (TBARS), glutathione (GSH), serotonin metabolite (5-HIAA), catalase, and the activity of Ca+2, and Mg+2 ATPase using validated methods. TBARS, H2O2, and GSH were found to be significantly decreased in the cortex and cerebellum/medulla oblongata of the groups treated with CP and NAC. The total ATPase showed a significant increase in the lung and cerebellum/medulla oblongata, while 5-HIAA showed the same tendency in the cortex of the same group of animals. The increase in 5-HIAA and ATPase during NAC and CP administration resulted in brain protection. This effect could be even more powerful when membrane fluidity is increased, thus proving the efficacy of combined NAC and CP drug therapy, which appears to be a promising strategy for future chemotherapy in malnourished patients.
Challenges and Pitfalls of Research Designs Involving Magnesium-Based Biomaterials: An Overview
Authors: Hassan Nourhan , Krieg Thomas , Kopp Alexander , Bach Alexander D. , Kröger Nadja
Published: June 2024

Magnesium-based biomaterials hold remarkable promise for various clinical applications, offering advantages such as reduced stress-shielding and enhanced bone strengthening and vascular remodeling compared to traditional materials. However, ensuring the quality of preclinical research is crucial for the development of these implants. To achieve implant success, an understanding of the cellular responses post-implantation, proper model selection, and good study design are crucial. There are several challenges to reaching a safe and effective translation of laboratory findings into clinical practice. The utilization of Mg-based biomedical devices eliminates the need for biomaterial removal surgery post-healing and mitigates adverse effects associated with permanent biomaterial implantation. However, the high corrosion rate of Mg-based implants poses challenges such as unexpected degradation, structural failure, hydrogen evolution, alkalization, and cytotoxicity. The biocompatibility and degradability of materials based on magnesium have been studied by many researchers in vitro; however, evaluations addressing the impact of the material in vivo still need to be improved. Several animal models, including rats, rabbits, dogs, and pigs, have been explored to assess the potential of magnesium-based materials. Moreover, strategies such as alloying and coating have been identified to enhance the degradation rate of magnesium-based materials in vivo to transform these challenges into opportunities. This review aims to explore the utilization of Mg implants across various biomedical applications within cellular (in vitro) and animal (in vivo) models.
Effects on Metallization of n+-Poly-Si Layer for N-Type Tunnel Oxide Passivated Contact Solar Cells
Authors: Wang Qinqin , Gao Beibei , Wu Wangping , Guo Kaiyuan , Huang Wei , Ding Jianning
Published: June 2024

Thin polysilicon (poly-Si)-based passivating contacts can reduce parasitic absorption and the cost of n-TOPCon solar cells. Herein, n+-poly-Si layers with thicknesses of 30~100 nm were fabricated by low-pressure chemical vapor deposition (LPCVD) to create passivating contacts. We investigated the effect of n+-poly-Si layer thickness on the microstructure of the metallization contact formation, passivation, and electronic performance of n-TOPCon solar cells. The thickness of the poly-Si layer significantly affected the passivation of metallization-induced recombination under the metal contact (J0,metal) and the contact resistivity (ρc) of the cells. However, it had a minimal impact on the short-circuit current density (Jsc), which was primarily associated with corroded silver (Ag) at depths of the n+-poly-Si layer exceeding 40 nm. We introduced a thin n+-poly-Si layer with a thickness of 70 nm and a surface concentration of 5 × 1020 atoms/cm3. This layer can meet the requirements for low J0,metal and ρc values, leading to an increase in conversion efficiency of 25.65%. This optimized process of depositing a phosphorus-doped poly-Si layer can be commercially applied in photovoltaics to reduce processing times and lower costs.
Investigation of Particle Rotation Characteristics and Compaction Quality Control of Asphalt Pavement Using the Discrete Element Method
Authors: Zhang Zhi , Dan Hancheng , Shan Hongyu , Li Songlin
Published: June 2024

The compaction of asphalt pavement is a crucial step to ensure its service life. Although intelligent compaction technology can monitor compaction quality in real time, its application to individual asphalt surface courses still faces limitations. Therefore, it is necessary to study the compaction mechanism of asphalt pavements from the particle level to optimize intelligent compaction technology. This study constructed an asphalt pavement compaction model using the Discrete Element Method (DEM). First, the changes in pavement smoothness during the compaction process were analyzed. Second, the changes in the angular velocity of the mixture and the triaxial angular velocity (TAV) of the mortar, aggregates, and mixture during vibratory compaction were examined. Finally, the correlations between the TAV amplitude and the coordination number (CN) amplitude with the compaction degree of the mixture were investigated. This study found that vibratory compaction can significantly reduce asymmetric wave deformation, improving pavement smoothness. The mixture primarily rotates in the vertical plane during the first six passes of vibratory compaction and within the horizontal plane during the seventh pass. Additionally, TAV reveals the three-dimensional dynamic rotation characteristics of the particles, and the linear relationship between its amplitude and the pavement compaction degree aids in controlling the compaction quality of asphalt pavements. Finally, the linear relationship between CN amplitude and pavement compaction degree can predict the stability of the aggregate structure. This study significantly enhances quality control in pavement compaction and advances intelligent compaction technology development.
Epidemiological analysis of human and animal originated Mycobacterium bovis subspecies by spoligotyping and mycobacterial interspersed Repetitive Unit-Variable Number of Tandem Repeat (MIRU-VNTR) methods
Authors: Altun Derya , Pir Halil , Yardımcı Hakan
Published: June 2024

This study aims to investigate the genotypic similarities between human and animal-originated isolates by spoligotyping and 24 loci MIRU-VNTR for molecular epidemiological analysis of Mycobacterium bovis isolates. In this study, isolates were obtained between 2019 and 2022 from 58 humans and 50 bovines. Initially identified with the GenoType MTBC kit, all isolates were genotyped using spoligotyping and 24 loci Mycobacterial Interspersed Repetitive Unit-Variable Number of Tandem Repeat (MIRU-VNTR) methods and their lineage relationships were illustrated in the dendrogram. When subjected to the spoligotyping method, the human and animal-originated isolates were revealed eight distinct clusters and 29 different genotypes. Notably the most prevalent genotypes were SIT1118/SB0989 (19.23%), SIT482/SB0120 (16.35%), SIT685/SB0288 (12.5%) detected in both human and animal-originated isolates. SB1593 (12.5%) was exclusively identified in animal-originated isolates. Additional genotypes included SIT3529/SB0920, SIT1185/SB0897, SIT3710/SB1595, SIT688/SB0129, SIT3687/SB1625, SB0419, SB2466, SB1231, and SB2510. MIRU-VNTR analysis resulted in nine distinct clusters and 55 different genotypes. ETR-C, QUB2163b, QUB26, and Mtub04 exhibited the highest allelic diversity, while MIRU02, MIRU20, MIRU24, MIRU27, and MIRU39 did not display allelic diversity. When the molecular typing results of the 95 isolates, tested with all three methods, 93.7 % agreement was observed between methods. In conclusion, it was determined that both tests could be safely employed. The presence of similar genotypes in humans and animals underscores the potential zoonotic transmission of Mycobacterium bovis.
Métodos geométricos para estimar alturas de fustales y árboles maduros en Acraquia, Perú
Authors: Gutiérrez-Collao Jairo Edson , Saldaña-Chafloque Charles Frank , Tello Zevallos Wilfredo , Palomino Santos Evelyn Ruth , Carrasco Llaique Camila Valentina , Chavarría Márquez Esmila Yeime
Published: June 2024

La evaluación del crecimiento en altura es imprescindible en la optimización de la ordenación forestal y la obtención del producto maderable. Objetivo. Comparar los métodos geométricos leñador, de unidades, 1:10 y de sombras, para estimar alturas de fustales y árboles maduros de una plantación de Eucalvptus spp en Acraquia, Perú. Materiales y Métodos. El diseño de la investigación fue experimental al azar, con un arreglo factorial 4X2. Se estimó la altura de 320 individuos de una plantación de 11 años de edad, se utilizaron estacas de 3 m y cinta métricas de 30 m. Para los análisis estadísticos se usaron la prueba de Kolmogorov-Smirnov, la de Levene y Duncan. Los resultados indican que no existe diferencia significativa entre los métodos geométricos, pero sí entre fustales y árboles maduros. Conclusiones. La estimación de alturas puede efectuarse, utilizando cualquiera de los métodos comparados, lo que contribuye a optimizar el uso del tiempo, personal y equipos, ya que no es necesario invertir en uno en particular.
Gestión social y la calidad de vida en asociaciones rurales
Authors: Cusme Acosta Angélica Mariuxy , López Basurto Damaris Nahomi , Montesdeoca Arteaga Deborah Valerie , Márquez Bravo Yessenia Johana
Published: June 2024

La Gestión Social se centra en la gestión empresarial que se enfoca en la responsabilidad social y el impacto social de las empresas en la sociedad. El artículo examina la Gestión Social y su impacto en la Calidad de Vida de los miembros de la Asociación Agropecuaria “El Pueblito”. La investigación adopta un enfoque mixto, combinando métodos cualitativos y cuantitativos. Los resultados revelan desafíos demográficos, educativos y de salud con una correlación significativa de 0.982 entre Gestión Social y Calidad de Vida. Las dimensiones con mayor fuerza fueron: Salud, Trabajo, vivienda y educación. Se identifican problemas prioritarios, destacando la importancia de la salud y los ingresos. Es necesario que las Asociaciones evalúen periódicamente la gestión social para que fortalezcan su accionar social y propender a un bienestar colectivo
Influencia de la gestión de costos en la toma de decisiones en las mypes
Authors: Zegarra Quesada Giuliana Milagros
Published: June 2024

En el paisaje económico contemporáneo, las micro, pequeñas y medianas empresas (Mypes) representan una columna vertebral esencial para la prosperidad y el desarrollo de las naciones. Por ello, el objetivo de este estudio es analizar la influencia de la gestión de costos en la toma de decisiones en las Mypes constructoras de Lima Metropolitana. El método empleado fue de tipo descriptivo-aplicado, con enfoque cuantitativo, la muestra se seleccionó por conveniencia, eligiendo 8 empresas, se utilizaron como instrumentos dos cuestionarios y como técnica la encuesta con base a la escala de Likert. Al analizar los resultados, se observó que ambos p-valores asociados a las variables son superiores al nivel de significancia comúnmente utilizado de 0.05. Específicamente, el p-valor para la "Gestión de costos" es de 0.540, mientras que para "Toma de decisiones" es de 0.583. Se concluye la gestión de costos emerge como un pilar fundamental que influye de manera significativa en la toma de decisiones estratégicas en las Mypes constructoras de Lima Metropolitana.
Educação Ambiental e oralidades: a construção do Caparaó Capixaba pelos relatos das(os) educadoras(es)
Authors: Araujo Junior Aramis Cortes de , Cid Eduardo Fausto Kuster , Pinto Sabrine Lino
Published: June 2024

O presente artigo tem como objetivo apresentar a história de construção do Caparaó capixaba a partir das oralidades expostas por autoras(es) que estiveram à frente de todo este processo iniciado há mais de trinta anos. O ponto de convergência para isso foi a mobilização em prol da abertura de uma portaria do lado do estado do Espírito Santo que desse acesso ao Pico da Bandeira, exclusivo, até então, pelo lado mineiro. Utilizamos como metodologia a história oral para a realização das entrevistas com as(os) selecionadas(os), juntamente com pesquisas em fontes documentais, trabalhos acadêmicos e reportagens. Concluímos com a importância desse processo e as suas repercussões até os dias atuais.
Experiências em Educação Ambiental no Instituto de Educação Ciência e Tecnologia do Maranhão (IEMA), Bacabal
Authors: Silva Maria Laiane do Nascimento , Silva Karla Cristina Sousa e
Published: June 2024

Este trabalho tem como objetivo relatar e divulgar as experiências em Educação Ambiental implementadas no Instituto de Educação Ciência e Tecnologia do Maranhão, na cidade de Bacabal, Maranhão, utilizando diversas estratégias de aprendizagem, como metodologias ativas e Aprendizagem Baseada em Projetos. As ações foram desenvolvidas por meio de disciplinas eletivas, projetos de pesquisa e evento de exposição de projetos dos alunos relacionados ao tema. As ações contribuíram para formação de pessoas mais cuidadosas com o ambiente ao seu redor, além de incentivar os alunos a pensarem nos problemas vivenciados no dia a dia da escola e da comunidade e a propor soluções possíveis de serem executadas.
Educação Ambiental no desenvolvimento das mudanças climáticas: um estado da arte
Authors: Taverna Maira Rosenente , Pedroso Daniele Saheb
Published: June 2024

Os impactos ambientais ligados as mudanças climáticas veem sendo amplamente discutidos na imprensa, discutindo questões sociais que esta influência. O presente estudo caracteriza-se como um Estado da Arte, ao qual analisou as produções dos anos de 2018 a 2022 referentes as questões de Mudanças Climáticas e Educação Ambiental (EA) nos indexadores da Biblioteca de Tese e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e da Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). Assim, chegou-se a 19 resultados em que foi identificado questões voltadas a educação; políticas públicas; percurso histórico e metodológico possibilitando caracterizar a EA pelos textos.
Educação Ambiental em museus de ciências: uma oficina no Museu da Amazônia – Manaus (AM)
Authors: Almeida Marley Guerreiro de , Barros Alessandra Trindade Cid , Negreiros Klicia Valery de Araújo , Gadelha Lieda kellen Medeiros , Batttaini Vivian
Published: June 2024

Este trabalho traz reflexões sobre a potencialidade da Educação Ambiental (EA) em Museus de Ciências. Nesse intuito, demonstra como a intencionalidade de trabalhar com Educação Ambiental, a partir da temática da biodiversidade, materializa-se numa oficina realizada no Museu da Amazônia (Musa). O relato destaca a abordagem da EA, incorporando aspectos biológicos, socioculturais, sociais, políticos, afetivos e sensíveis. A escolha do Musa ressalta a importância dos Museus de Ciência na promoção da EA. Espera-se que o texto inspire reflexões sobre como a Educação Ambiental pode ser potente em Museus de Ciências e em ambientes ricos em biodiversidade, em especial, ações realizadas na Amazônia.
Refloreste-se – um projeto de Educação Ambiental na sensibilização para a produção e doação de mudas de árvores no ensino básico
Authors: Medeiros Francisco Diego Mendonça , Tabosa Wyllys Abel Farkatt
Published: June 2024

Frente a um cenário da perda do pensar as próprias ações, perdemos o autocuidado existencial enquanto indivíduo, enquanto sociedade e enquanto espécies em coexistência. Nesse contexto, o Projeto REFLORESTE-SE, que tem como metáfora um "reflorestamento" das ideias nos sujeitos, teve como objetivo promover a consciência do indivíduo como pertencente ao meio ambiente por meio da criação de um viveiro de plantas permanente. O Projeto foi aplicado em uma escola da rede municipal em São Gonçalo do Amarante/RN. Os alunos demonstraram a possibilidade de mudança de hábitos de forma orgânica, uma vez presente a constância de hábitos e valores relacionados ao cuidado ambiental empregados pela Educação Ambiental no cotidiano das salas de aula.
Marés de mudança: Educação Ambiental crítica no Ensino Médio Integrado em Pesca
Authors: Maia Rafaela Camargo , Silva Gustavo Gleidson Nascimento
Published: June 2024

O presente estudo abordou a implementação da Educação Ambiental Crítica no Ensino Médio Integrado em Pesca. Realizado na Praia da Lagoa da Volta, Acaraú, Ceará, contou com a participação de alunos, professores, Secretaria de Meio Ambiente e comunidade local. Utilizou-se uma sequência didática com aulas teóricas e práticas, incluindo atividades de campo e discussões. A Educação Ambiental crítica enriqueceu o currículo, formando cidadãos e profissionais comprometidos com a sustentabilidade. Os alunos identificaram impactos antrópicos, promovendo a troca de conhecimentos e a reflexão sobre esses impactos no ambiente costeiro e marinho, com implicações para a pesca.
رحلات المحدثين وأثرها في كشف العلة
Authors: الحازمي عبدالرحمن بن عبدالله
Published: June 2024

فكرة البحث: الرئيسة بيان أثر معرفة رحلات المحدثين في كشف العلة في الحديث والقرائن الدالة على ذلك . أهمية البحث: تكمن أهمية البحث في أن تحديث الراوي أثناء سفره قد يؤثر على إتقانه للحديث ووقوع الوهم في حديثه، ولكن لا يحكم بذلك إلا مع القرائن الدالة على الوهم وذلك يفيد عند الحكم على الأحاديث، وفي الترجيح بين الروايات المتعارضة. مشكلة البحث: تتمثل إشكالية البحث في أن تحديث الراوي أثناء سفره ليس علة بذاته ولكنه مظنة وقوع العلة،  فما المنهج الصحيح في كشف العلة. أهداف البحث: يهدف البحث إلى بيان أثر معرفة الرحلات في كشف العلة واستنتاج القرائن الدالة عليها، وأشهر الرواة الذين وقع منهم الوهم أثناء رحلاتهم. منهج البحث: اقتضت طبيعة البحث سلوك المنهج الوصفي التحليلي الاستنباطي. الاستنتاجات: يرى الباحث أن الوهم في الروايات قد وقع من بعض الرواة أثناء سفرهم، وأن الأحاديث لا تعل بمجرد تحديث الراوي أثناء رحلته بل لابد من القرائن الدالة على الوهم. أبرز النتائج: توصل الباحث إلى أن معرفة تحديث الراوي أثناء رحلته يساعد في الكشف عن العلة وبالتالي يمكن الترجيح بين الروايات المتعارضة، وأن من أبرز القرائن الدالة على الوهم يكون له كتب يرجع إليها في بلده فيحدث منها ثم يرحل بدونها فيُحَدِّث من حفظه دون الرجوع إليها، أو يُحَدِّث بما ليس في كتبه، أو يخالف ما فيها، أو أن يأخذ كتابه معه فيُدْخَل في كتابه ما ليس منه فيحدث منه، أو أن يُلقن فيقبل التلقين، أو أن يُحدث بما لا يعرفه طلابه الملازمون له في بلده، أو أن يتفرد بالحديث في غير بلده، أو ينكر عليه أهل بلده ما حدث به أثناء رحلته.
أثر وفاة الشخص المستفيد من القرض الإسكاني دراسة فقهية قانونية الكويت أنموذجاً
Authors: بن عيسى داود سلمان
Published: June 2024

فكرة الدراسة بيان أثر وفاة الشخص المستفيد من القرض الإسكاني من المواطنين الكويتيين من حيث استيفاء القرض بعد الوفاة، وأهمية الدراسة تكمن في أن هذه القروض الحسنة الحكومية لها أحكام بعد وفاة المقترض قبل السداد ولما كانت الذمة معلقة بسداد هذه الديون، التي تُصرف في أعمار متأخرة؛ لأن الأقساط يسيرة مقارنة مع قيمة القرض، فإن عامة المقترضين لن يستطيعوا سداد باقي قيمة القروض، وتهدف الدراسة إلى بيان الأثر الفقهي الشرعي والقانوني في حال عدم سداد الديون المتعلقة بذمة المقترض، لهذا درس الباحث أثر عدم سداد القرض حالاً بعد الوفاة، من خلال ربط النصوص الشرعية والقانونية، وتوضيح المعاني اللغوية والاصطلاحية للألفاظ، وبيان النظام التعاقدي بين الأفراد والحكومات، والخلاف الفقهي فيها، واستخراج المعاني الراجحة في تقرير الآراء والأحكام، وبيان المقصد الشرعي لسداد الديون، وكانت مشكلة البحث مدارها على هذا السؤال ما أثر الدّين المؤجل على وفاة المقترض؟ والمنهج المتبع هو الوصفي التحليلي الاستنباطي، وتوصل الباحث إلى أن المقترض يتأثر سلباً عند اقتراضه وإن كان قرضاً حسناً، فينبغي ألا يغتر بالدنيا مقابل راحته بعد موته، لذلك يرى الباحث النظر في التشريعات التي يمكن أن تساعد في إيجاد قانون يؤمن على هذه الديون، أو أن تتحملها الدولة ليتخلص المقترض من هذه الآثار الشرعية المترتبة عليه، وأبرز نتيجة يمكن استنتاجها هي تأثر المستفيد شرعياً بعد وفاته إن لم يوف الدين المستحق عليه.
التكييف الفقهي لمعاملة المتسوق الشخصي
Authors: الخنة سلطان فهد
Published: June 2024

فكرة البحث الرئيسة هي: دراسة قضية المتسوق الشخصي في مختلف عمليات الشراء وبيان أحكامها الفقهية، وتكمن أهمية البحث في أنه يتعرض لهذه المعاملة الحادثة ويربط بينها وبين عقود الفقه المشروعة، ويبين إلى أي مدى تتفق هذه المعاملة مع هذه العقود، وأنه يفصّل صور هذه المعاملة ويبين أيها أقرب لتحقيق مقاصد الشريعة ومقاصد المكلفين في الوقت نفسه. وأما مشكلة البحث فتدور حول التوصيف الفقهي لمعاملة المتسوق الشخصي ومدى ملاءمتها لقواعد العقود في الشريعة الإسلامية، وتتمثل أهداف البحث في التعرف على مفهوم المتسوق الشخصي وصورة هذه المعاملة، وكذلك بيان أحكام الصور المختلفة للمتسوق الشخصي، بالإضافة إلى تخريج عقد المتسوق الشخصي على أساس عقد السلم.  أما بالنسبة لمنهج البحث فهو المنهج الوصفي التحليلي حيث يجمع المادة العلمية المتعلقة بقضية البحث ثم يحلل هذه المادة ويستنتج منها الأحكام والنتائج التي تفيد في تقريب القضية والتعريف بخصائصها وأحكامها الشرعية. وقد خلص البحث إلى نتائج منها أنه من خلال التحليل الفقهي تبين أن معاملة المتسوق الشخصي تدور في فلك الإجارة والوكالة أو اجتماعهما معا، في أغلب صورها وهي معاملة جائزة لا محظور فيها إذ إجارة الأشخاص جائزة بالإجماع، وكذلك الوكالة ولا يلزم محظور باجتماعهما معا، وتوصي الدراسة بتوجيه البحوث نحو عمليات البيع المستحدثة خاصة ما يتعلق بالبيع عبر شبكة الإنترنت وما يتبع ذلك من طرق دفع وتسليم وتسلم، وكذلك بدراسة آليات الدفع الحديثة وما في حكمها ومعناها.
Analyzing the Effect of Environmental Change and Resilience towards Education among Children During the Post-Pandemic Situation
Authors: Jerome Asir D , Azariah Kirubakaran S
Published: June 2024

Education among children is the cornerstone of societal progress and individual empowerment. It serves as the foundation upon which young minds develop the knowledge, skills, and values necessary to thrive in an ever-evolving world.Education among children is the cornerstone of societal progress and individual empowerment. It serves as the foundation upon which young minds develop the knowledge, skills, and values necessary to thrive in an ever-evolving world. Moreover, education fosters critical thinking and problem-solving skills. In an era defined by rapid technological advancements and complex global challenges, the ability to analyze information, evaluate evidence, and think critically is more important than ever. By engaging with diverse perspectives and challenging assumptions, children learn how to navigate ambiguity, make informed decisions, and address real-world problems. Education cultivates a mindset of curiosity, inquiry, and resilience, enabling children to adapt to changing circumstances and thrive in an increasingly interconnected world
Man of Action: Murray N. Rothbard’s Contributions to the Theory of Entrepreneurship
Authors: D'Andrea Fernando M
Published: June 2024

Even though entrepreneurship underlies Rothbard’s economic theorizing, his contributions to this topic are spread among many writings. This paper traces a comprehensive idea of Rothbard’s “Man of Action,” the capitalist-entrepreneur in the causal-realist tradition of the Austrian School, organizing his thinking. Rothbard defines the entrepreneur as the economic agent who judges at the present about the future and directs production processes by controlling and allocating productive resources in search for profit. By organizing his ideas, I demonstrate how they differ from arguably similar approaches—notably Kirzner’s and Schumpeter’s—and argue that his strand of theorizing is the one in line with praxeology in the lineage of Menger, Böhm-Bawerk and Mises. I show that his contributions influenced others and are reflected in contemporaneous developments in both causal-realist and mainstream discussions. To close, I suggest how to use his ideas to continue to advance the theoretical understanding of the engine of the market process.
Estado, empresas y factores geopolíticos en el sendero de desarrollo de las redes 5G en Argentina
Authors: Borrastero Carina
Published: June 2024

El objetivo de este trabajo es analizar las características y resultados de la intervención estatal, en su vínculo con la actividad de las empresas que están operando en Argentina en torno al despliegue de redes 5G, reconociendo la incidencia del complejo contexto tecno-productivo y geo-político en que dicho proceso se desenvuelve hasta el presente. Son casi inexistentes los antecedentes académicos detectados sobre el tema.
Se desarrolló un estudio cualitativo exploratorio basado en fuentes secundarias, a través del análisis bibliográfico, documental y teórico, que permitió plantear un recorrido histórico retrospectivo del fenómeno para proveer una explicación provisoria –ya que se trata de un proceso reciente y en marcha– del sendero de desarrollo del sector. La hipótesis de trabajo es que el Estado conserva un margen de maniobra para vincularse con los distintos actores bajo una estrategia de neutralidad geopolítica, manteniendo hasta el momento su soberanía de adopción tecnológica en el territorio.
ANALYSIS OF ACCESSIBILITY OF ONLINE NEWS WEBSITES USING THE FUZZY ANALYTICAL HIERARCHY PROCESS (FAHP) AND SIMPLE ADDITIVE WEIGHTING (SAW) METHOD
Authors: Mukarromah Firma , Parga Zen Bita , Hebrasianto Permadi Dimas Fanny
Published: June 2024

Teknologi saat ini berkembang cukup pesat, khususnya pada kasus penyebaran informasi melalui jaringan internet yang menjangkau masyarakat luas menggunakan website. Website news merupakan media penyampaian informasi berita memiliki peran penting dalam kehidupan sehari-hari, dengan demikian diperlukannya sebuah website yang mempunyai kualitas yang tinggi, akurasi dan cepat pada penyajiannya. Aksesibilitas adalah hal yang sangat mendasar untuk mengukur kualitas sebuah situs website khususnya website news sehingga dapat memberikan kemudahan kepada user pada saat mengaksesnya. Untuk menjawab permasalahan tersebut, diperlukan pengukuran guna mengamati prioritas dari semua kriteria dengan memanfaatkan konsep fuzzy yang bersifat subjektif. Fuzzy Analytical Hierarchy Process (FAHP) merupakan teknik yang digunakan untuk mendapatkan nilai bobot dari masing-masing kriteria. Dalam penelitian ini, empat situs web digunakan sebagai objek penelitian, antara lain Kompas.com, CNNIndonesia, Tempo.co dan Bisnis.com. Dari penelitian ini didapatkan sebuah hasil akhir yaitu website Bisnis yang menduduki ranking pertama dengan skor tertinggi 0,63 dan untuk ranking terakhir dengan memperoleh skor 0,11 diperoleh pada website Tempo.co. Permasalahan yang sering terjadi yang mempengaruhi aksesibilitas website adalah banyaknya elemen yang tidak diperbolehkan untuk digunakan pada posisi yang salah atau elemen yang digunakan kurang lengkap sehingga banyak tabel kosong yang menyalahi aturan WCAG 2.1.A 4.1.1 bagian 508(2017)A 4.1.1 dan sulit untuk digunakan oleh user.
Supporting Student Decisions on Learning Recommendations: An LLM-Based Chatbot with Knowledge Graph Contextualization for Conversational Explainability and Mentoring
Authors: Abu-Rasheed Hasan , Abdulsalam Mohamad Hussam , Weber Christian , Fathi Madjid
Published: June 2024

Student commitment towards a learning recommendation is not separable from their understanding of the reasons it was recommended to them; and their ability to modify it based on that understanding. Among explainability approaches, chatbots offer the potential to engage the student in a conversation, similar to a discussion with a peer or a mentor. The capabilities of chatbots, however, are still not sufficient to replace a human mentor, despite the advancements of generative AI (GenAI) and large language models (LLM). Therefore, we propose an approach to utilize chatbots as mediators of the conversation and sources of limited and controlled generation of explanations, to harvest the potential of LLMs while reducing their potential risks at the same time. The proposed LLM-based chatbot supports students in understanding learning-paths recommendations. We use a knowledge graph (KG) as a human-curated source of information, to regulate the LLM’s output through defining its prompt’s context. A group chat approach is developed to connect students with human mentors, either on demand or in cases that exceed the chatbot’s pre-defined tasks. We evaluate the chatbot with a user study, to provide a proof-of-concept and highlight the potential requirements and limitations of utilizing chatbots in conversational explainability.
(Auto)portrait(s). Dürrenmatt et les arts visuels
Authors:   , Minder Myriam
Published: June 2024

This is a first study of Friedrich Dürrenmatt (1921-1990) as both a graphic artist and a painter. The famous Swiss writer drew and painted throughout his life, producing a substantial visual production. Yet while he claimed to be a writer, he insisted all his life that he was not a painter. How is this apparent contradiction to be interpreted? What is Dürrenmatt's relationship with the visual arts on the one hand, and his own paintings on the other? The first part of this thesis examines Dürrenmatt's knowledge of and affinity for the visual arts, offering a glimpse into his imaginary museum (André Malraux). The second part examines Dürrenmatt's practice of drawing and painting, in terms of its creative processes, its recipients and its functions. The reception of this graphic and painted work is also examined, as is Dürrenmatt's discourse on his artwork. This provides an insight into his attitude to the visual arts and his identity as a painter, influenced by the image of the artist (Ernst Kris/Otto Kurz). Far from ignoring the importance of Dürrenmatt's literary body of work, this thesis differs from other studies that focus on his artwork in relation to his literary production, or as an artist with a dual vocation. The choice of sources consists of Dürrenmatt's graphic and painted work, his library, his personal diaries, his correspondence, his exhibition files, his own collection of third-party works of art, interviews with people who knew him, a corpus of press articles, as well as the artist's own writings about the visual arts or his artwork. One of the keys to understanding Dürrenmatt's relationship with his paintings is the analysis of his self-portraits, the way in which the artist chooses to present himself to the world. Throughout Dürrenmatt's graphic and artwork, the self-portrait offers the artist a mirror that he chooses to hold up to both his audience and himself. A reflexive genre above all, it allows him to distance himself and question his identity. The study of these self-portraits shows how Dürrenmatt, as an expert on the models of self-representation in art history, plays with the typology of the genre and its diversity. It also shows the gradual development of his stance towards the visual arts and his identity as a painter. The portrayal presented here is not static, but takes into account the evolution of his posture as an artist over time.
Hubungan Emotional Quotient dengan Indeks Prestasi Kumulatif Mahasiswa Angkatan 2020 Fakultas Kedokteran Universitas Sam Ratulangi
Authors: Winengko Livia C. , Homenta Heriyannis , Berhimpon Siemona L. E.
Published: June 2024

Abstract: Emotional quotient (EQ) is the ability to understand and control emotions in oneself and others. The essentials to develop EQ are superior in medical students due to future work professions that require skills to maintain interactions with patients and other medical workers. This study aimed to evaluate the correlation between EQ and the Cumulative Achievement Index in medical students class of 2020, Faculty of Medicine, Universitas Sam Ratulangi. This was an observational  and analytical study with a cross-sectional design. Samples were 160 students from the class of 2020 at the Faculty of Medicine, Universitas Sam Ratulangi. The EQ value was measured using the TEIQue-SF instrument, while the Cumulative Achievement Index was obtained from the student transcripts. The result showed that most of the students have moderate EQ (77.5%) and Cumulative Achievement Index that predicated with a compliment (55%). There was an insignificant correlation between EQ and the Cumulative Achievement Index (p=0.506; r=0.053), and the correlation was positive and very weak. In conclusion, there is a positive but insignificant correlation between EQ and Cumulative Achievement Index among students class of 2020, Faculty of Medicine, Universitas Sam Ratulangi.
Keywords: Emotional Quotient; Cumulative Achievement Index; Trait Emotional Intelligence Questionnaire-Short Form
 
Abstrak: Emotional Quotient (EQ) adalah kemampuan memahami dan mengendalikan emosi pada diri sendiri dan orang lain. Kebutuhan untuk mengembangkan EQ yang lebih tinggi pada mahasiswa Fakultas Kedokteran karena profesi kinerja ke depannya membutuhkan keterampilan guna membangun interaksi dengan pasien dan tenaga medis lainnya. Penelitian ini bertujuan untuk mengevaluasi hubungan EQ dengan Indeks Prestasi Kumulatif (IPK) mahasiswa angkatan 2020 Fakultas Kedokteran Universitas Sam Ratulangi (FK Unsrat). Penelitian ini menerapkan pendekatan observasional analitik dan studi potong lintang. Sampel penelitian ialah 160 mahasiswa angkatan 2020 FK Unsrat. Nilai EQ diukur menggunakan instrumen TEIQue-SF dan nilai IPK diperoleh dari transkip nilai mahasiswa. Hasil penelitian memperlihatkan bahwa sebagian besar mahasiswa memiliki EQ kategori sedang (77,5%) dan predikat IPK dengan pujian (55%). Terdapat hubungan tidak bermakna antara EQ dengan IPK kekuatan korelasi sangat lemah dan arah korelasi positif (p=0,506; r=0,053). Simpulan penelitian ini ialah terdapat hubungan positif yang tidak bermakna antara Emotional Quotient dengan Indeks Prestasi Kumulatif mahasiswa angkatan 2020 Fakultas Kedokteran Universitas Sam Ratulangi.
Kata kunci: Emotional Quotient; Indeks Prestasi Kumulatif; Trait Emotional Intelligence Questionnaire-Short Form
Reconstruction of Lower Eyelid in Basal Cell Carcinoma Case with Adjunctive Hyperbaric Oxygen Therapy: A Case Report
Authors: Chietra Yulius A. M. , Hatibie Mendy J. , Dali Ramli
Published: June 2024

Abstract: Basal cell carcinomas (BCCs) are the most common cancers in humans, caused by exposure to ultraviolet light and are associated with PTCH1 gene mutation. Its incidence rate significantly increases per year especially in elderly people. Several modalities are available for BCC treatment but surgery is still considered as the gold standard. Oxygen is mandatory for almost all wound healing processes, and oxygen substitution can be delivered in the form of hyperbaric oxygen (HBO) therapy. We presented a 70 years old woman with a major complaint of a tumor located in the left infrapalpebral region, below the left lower lash line with 5 years of evolution. Patient had clinical presentation of solid nodular basal cell carcinoma which was the most common clinical subtype. Patient was diagnosed as having BCC based on history taking, clinical findings, and histopathological examination. Surgical wide excision, skin flap, and HBO as the adjunctive therapy were performed on this patient. With these techniques, healing time was reduced, complications rates were low, and cosmetic outcome was much better. In conclusion, closing defects of BCC case with surgical wide excision and flap yields a remarkable outcome and an adjunctive HBO therapy after surgery optimizes the oxygenation, thus, the healing potential of tissue prior to surgery, and accelerates wound healing post operatively. A good result with short healing duration was observed.
Keywords: basal cell carcinoma; hyperbaric oxygen therapy; flap; wound healing
Coral Recruitment And Transplantation To Support Coral Reef Ecosystem Recovery (Overview)
Authors: Tuhumena Jeremias , Pangaribuan Rosa , Pane Lindon , Merly Sendy , Parenden Dedi , Tuhumena Lolita
Published: June 2024

Coral reefs are massive deposits of calcium carbonate (CaCO3) produced by coral animals.  Coral reefs in the water are easily damaged due to natural events and destrutive human activities in the water and the influence of upland.   The purpose of this paper is to provide information related to the recovery of coral reef ecosystems through coral recruitment and coral transplantation and the role of the community.  The method used is the quantitative method.  Recruitment and transplantation use media as a place to attach or bind coral fragments.  Coral recruitment is done by relying on the reproduction of the coral itself, while transplantation is done by taking coral fragments from the broodstock. The placement of coral recruitment and transplantation media needs to pay attention to water depth, brightness, substrate, sedimentation, and water current patterns.  In addition, the government, community, and related parties are needed to handle damage and maintain and manage coral reef ecosystems for sustainability.
Keywords: Coral Recruitment; Coral  Transplantation; Coral Reef
Abstrak
Terumbu karang merupakan  endapan massif kalsium karbonat (CaCO3) yang dihasilkan oleh hewan karang .  Terumbu karang di perairan mudah mengalami kerusakan akibat kejadian alam maupun kegiatan manusia yang bersifat destrutif di perairan maupun pengaruh dari lahan bagian atas (upland).   Tujuan penulisan ini yaitu untuk memberikan informasi terkait dengan pemulihan ekosistem terumbu karang  melalui rekrutmen karang dan transplantasi karang serta peran masyarakat.  Metode yang digunakan yaitu metode kuantitatif.  Rekrutmen dan transplantasi menggunakan media sebagai tempat penempelan maupun mengikat fragmen karang.  Rekrutmen karang dilakukan dengan mengandalkan reproduksi dari karang itu sendiri, sedangkan transplantasi dilakukan dengan mengambil fragmen karang dari indukan. Lokasi penempatan media rekrutmen dan transplantasi karang perlu memperhatikan kedalaman perairan, kecerahan, substrat, sedimentasi dan pola arus perairan.  Selain itu, peran pemerintah, masyarakat dan pihak terkait diperlukan untuk penanganan kerusakan, menjaga dan pengelolaan ekosistem terumbu karang untuk keberlanjutan.
Kata Kunci : Rekrutmen Karang; Transplantasi karang; Terumbu Karang
783 MHz fundamental repetition rate all-fiber ring laser mode-locked by carbon nanotubes
Authors: Dai Maolin , Liu Bowen , Ma Yifan , Shirahata Takuma , Yang Ruoao , Zhang Zhigang , Set Sze Yun , Yamashita Shinji
Published: June 2024

We demonstrate a 783 MHz fundamental repetition rate mode-locked Er-doped all-fiber ring laser with a pulse width of 623 fs. By using carbon nanotubes saturable absorber, a relatively low self-starting pump threshold of 108 mW is achieved. The laser has a very compact footprint less than 10 cm × 10 cm, benefiting from the all-active-fiber cavity design. The robust mode-locking is confirmed by the low relative intensity noise and a long-term stability test. We propose a new scheme for generating high repetition rate femtosecond optical pulses from a compact and stable all-active-fiber ring oscillator.
Interaction Design on Basic Hand Movement Training Game in Taekwondo Using User-Centered Design
Authors: Ramdani Rahmat Muhamad , Yuniarti Rezki , Komarudin Agus
Published: June 2024

This research will develop an interaction design for basic hand movement games in taekwondo with the hope that it can become an alternative physical exercise for hand stretching. UCD is one of the methods in interaction design that focuses on the user. By designing interactions in hand movement training games using the UCD method and present technology, it is hoped that this can be a stretch in the dense student activities. The results of the interaction design evaluation using UCD obtained an average of 90.24% for the 6th heuristic based on ten evaluation heuristics. Combining the UCD method at the design stage and utilizing present technology is an innovation in designing easy-to-use game-based interaction designs. The study results show that the UCD method for interaction design is suitable for use in the game design process.
Development of an Android-based Application as a Solution for Maternal Health
Authors: Tarsono  , Fachrie Muhammad
Published: June 2024

This research highlights the problem of lack of accessibility of health services for pregnant women, especially in consultations with doctors and access to pregnancy information. To overcome these challenges, the research aims to develop an application that allows pregnant women to access pregnancy information easily, consult with doctors, and monitor pregnancy progress efficiently. This research proposes the development of an Android-based application as a solution for health care for pregnant women, which uses an approach known as Rapid Application Development (RAD). RAD was chosen because of its reputation as a software development approach with rapid development capabilities and readiness to respond to change. Adopting the RAD method aims to create flexible and responsive applications that can adapt to changes that may occur over time. This learning and consultation application for pregnant women is very helpful for them to always know about their pregnancy. This application is also very useful for health workers. Health workers can quickly help patients at any time. Health workers can also provide advice regarding pregnancy by entering it into the application, which will be very helpful for mothers in maintaining their pregnancy. The research addresses the accessibility of health services for pregnant women. It is hoped that with this application, pregnant women will become more educated and guided about pregnancy so that cases of maternal and infant mortality in Indonesia will decrease.
Dopamind+: Mobile-Based Application to Prevent and Treat Mental Health Disorders in Adolescents
Authors: Rahmadiannisa Mutiara S. , Firdaus Fadli S. , Manaf Irfan M. , Putra Kadek W.P.
Published: June 2024

To achieve the third goal of the SDGs, which is to ensure a healthy life and promote well-being for individuals of all ages, mental health in Indonesia has been insufficiently addressed. Mental health disorders prevalent in the community include stress, depression, and even suicide. Factors triggering conditions, such as irregular sleep, especially among women, can affect the regularity of their menstrual cycles. Therefore, preventive measures are needed by creating the Dopamind+ application. The purpose of developing this application is to 1) Analyze the impact of the Dopamind+ application on users who are likely to experience mental health disorders, 2) Reduce the incidence of mental health disorders, 3) Support innovation in mental health issues by collaborating with technology, and 4) Create a mobile-based application that provides healthcare services and education, especially for teenagers. Hopefully, this application will help users access information, support, and mental health services. In addition, it can demonstrate the importance of cross-sector collaboration in providing holistic and integrated mental health services and has the potential to improve users' quality of life by reducing levels of stress, depression, and risk of suicide; in making this application, we used the design thinking method. This approach is used to understand user needs and design solutions better accordingly. The Empathize stages help in understanding the experiences and challenges faced by individuals regarding mental health. Define and identify the problems you want to solve and direct innovation. Ideate makes it possible to generate a variety of creative solution ideas. Prototype allows developers to test those ideas, and testing helps evaluate application performance and receive user feedback. The findings highlighted in this application are SOS, which will enable users to trigger emergency signals, and beacon signals, which will enable them to ask for help from those around them in mental health emergencies. The target users of the Dopamind+ application are classified based on age, gender, and diseases/genetics. Stakeholders in this application include health departments, social services, users, police, fire departments, developers, researchers, academicians, and relevant organizations. The limitations of the Dopamind+ application are that it uses the English language, requires a user email password, and employs features designed for all groups, especially teenagers prone to mental health issues. This application is accessible via mobile platforms such as Android and iOS. The features include Smart to-do list, Red Day tracker, Educare and Counseling, Virtual Community, Sleep tracker, SOS, and Stress tracker.
Deteksi Antusiasme Siswa dengan Algoritma Yolov8 pada Proses Pembelajaran Daring
Authors: Salma Kartika , Hidayat Syarif
Published: June 2024

The implementation of Face Emotion Recognition (FER) technology in online classes opens up new opportunities to effectively monitor students' emotional responses and adjust the teaching approach. Through FER, instructors can monitor students' emotional responses to learning materials in real-time and enable quick adjustments based on individual needs. Additionally, this technology can also be used to detect the level of enthusiasm or lack thereof among students towards the learning process, allowing for the optimization of teaching strategies. This study focuses on the implementation of the YOLOv8 algorithm in detecting students' enthusiasm, comparing the performance of YOLOv8n, YOLOv8s, YOLOv8m, and YOLOv8l models. Test results show that YOLOv8n performs the best with an accuracy rate of 95.3% and a fast inference time of 62ms, enabling real-time object detection. Thus, the application of YOLOv8 in this context aims to detect students' enthusiasm in real-time and allows instructors to quickly adjust their approach to meet students' needs. Furthermore, this research contributes to improving the quality of online learning by providing insights into students' emotional engagement and serving as a tool to help instructors better understand and respond appropriately to students' emotions during the online learning process.
Evaluasi User Interface Pada Sistem Informasi E-Kinerja Kabupaten Muara Enim Dengan Metode System Usability Scale (SUS)
Authors: Saputra Yudi , Suyanto  , Sopiah Nyimas , Wardani Kiky Rizky Nova
Published: June 2024

The benefits of evaluation are improving and achieving a goal and identifying problems with an information system by users. Many agencies use information systems as the backbone for disseminating information. This condition also occurs in the Muara Enim Regency Government, which uses the e-kinerja information system as a forum for distributing information on assessing the performance of State Civil Apparatus within the Muara Enim Regency Government. So the existence of an e-performance information system is very important because it concerns the performance of ASN itself. For this reason, this research will carry out an evaluation to find out or see the views of users regarding the form and appearance of the Muara Enim Regency e-performance information system. In carrying out this evaluation, the method used is the System Usability Scale (SUS) method. The results of this research will be in the form of statistical data relating to users' views of the Muara Enim Regency e-performance information system.