bluuebunny/crossref_metadata_2025 huggingface dataset:
THERMAL PROPERTIES OF HEAVY OIL SATURATED RESERVOIR ROCKS BEFORE AND AFTER HIGH TEMPERATURES TREATMENT
Authors:   High-Temperature Joint Institute of the Russian Academy of Sciences, Abdulagatova Z.Z. , Kallaev S.N. ,   Institute of Physics of the Dagestan Scientiﬁc Center of the Russian Academy of Sciences, Omarov Z.M. ,   Institute of Physics of the Dagestan Scientiﬁc Center of the Russian Academy of Sciences, Bakmaev A.G. ,   Institute of Physics of the Dagestan Scientiﬁc Center of the Russian Academy of Sciences, Grigor’ev B.A ,   Gubkin Russian State University of Oil and Gas, National Research University, Abdulagatov I.M. ,   High-Temperature Joint Institute of the Russian Academy of Sciences,   Dagestan State University
Published: January 2021

This paper aims to study of the variation of key thermal properties (thermal diffusivity, heat capacity, and derived values of thermal conductivity) of heavy oil saturated reservoir rock sample before and after high temperature treatment. A laser ﬂash method (LFA 457) and differential scanning calorimeter (DSC 204 F1) were employed to study of the temperature effect on the thermal diffusivity ( ) and heat capacity ( ) of natural heavy oil reservoir rock sample. The measurements of the thermal – diffusivity have been made over the temperature range from (296 to 1023) K. The isobaric heat capacities of the same sample were measured in the temperature range from (299 to 768) K. Uncertainties of the measurements are 3 % and 1 % for and , respectively. The measurements were made in heating and cooling runs. Significant difference between the measured properties before and after thermal treatment was observed. Measured values of thermal diffusivity ( ) and heat capacity ( ) together with density data ( ) were used to calculate the derived very important properties of rock sample (thermal conductivities, ) using well-known thermodynamic relation, . A relationship between the temperature behavior of the thermophysical properties ( , , ) and the physical-chemical processes (thermal decomposition of pore heavy oil and volatilization of residual water absorbed in the pore walls) occurring in the rock pores during heating in distinct temperature ranges has been studied. The sig-nificant effect of thermal decomposition and dehydration processes on the temperature behavior of measured values of thermal -diffusivity and heat-capacity of oilbearing reservoir rock sample at high temperatures (above 680 K) was experimentally observed.
SOME ASPECTS OF DIFFERENTIATION OF THE IONIC CONDUCTIVITY OF MICA MINERALS
Authors:   INSTITUTE FOR PROBLEMS OF GEOTHERMY AND RENEWABLE ENERGY - BRANCH OF THE JOINT INSTITUTE OF HIGH TEMPERATURES RAS, Guseinov A.A.
Published: January 2021

Исследованы основные факторы, приводящие к дифференциации параметров электропроводности слюдистых минералов, играющих важную роль в формировании свойств земной коры. Основными факторами, приводящим к различию по величине ионной проводимости биотитов, флогопитов и мусковитов являются, как различи катионного состава октаэдрических позиций, так и угол наклона оси гидроксила ОН относительно слоя в кристаллической решетке минерала. Эти факторы находят отражение в одном фундаментальном термодинамическом параметре исследованных минералов – энтропии.
GAMMA RESONANCE ANALYSIS OF THE PRESENCE AND STATE OF IRON IN MINERAL WATERS OF DAGESTAN
Authors:   Institute of Physics Kh.I. Amirkhanova - a separate division Dagestan Federal Research Center RAS, Huseynov M.M.
Published: January 2021

Методом мёссбауэровской спектроскопии исследованы сухие остатки минеральных вод Дагестана с целью обнаружения и анализа физико-химического состояния железа в них. Результаты исследований показали наличие фракций железа в исследованных водах в виде отдельных оксидов, концентрация и состояние которых практически мало отличаются для различных вод.
SOLAR AIR HEATERS WITH HEAT ACCUMULATORS
Authors:   INSTITUTE FOR PROBLEMS OF GEOTHERMY AND RENEWABLE ENERGY - BRANCH OF THE JOINT INSTITUTE OF HIGH TEMPERATURES RAS, Dibirov Ya.A. , Musaeva P.A. ,   INSTITUTE FOR PROBLEMS OF GEOTHERMY AND RENEWABLE ENERGY - BRANCH OF THE JOINT INSTITUTE OF HIGH TEMPERATURES RAS, Iskenderov E.G. ,   INSTITUTE FOR PROBLEMS OF GEOTHERMY AND RENEWABLE ENERGY - BRANCH OF THE JOINT INSTITUTE OF HIGH TEMPERATURES RAS, Zeynalov M.Sh. ,   INSTITUTE FOR PROBLEMS OF GEOTHERMY AND RENEWABLE ENERGY - BRANCH OF THE JOINT INSTITUTE OF HIGH TEMPERATURES RAS
Published: January 2021

Разработан и сконструирован экспериментальный образец принципиально новой установки солнечного воздухонагревателя с фазопереходным тепловым аккумулятором, предназначенный для высушивания плодоовощной продукции, позволяющий, используя только энергию солнечной радиации, круглосуточно вырабатывать нагретый воздух с заданными термическими параметрами. Примененная функциональная схема испытания образца установки с использованием современного цифрового приборного оснащения позволяет получить достоверные результаты данных ряда параметров функционирования данной установки в естественных условиях.
RES DEVELOPMENT IN THE REPUBLIC OF DAGESTAN - A NEW STAGE
Authors:   Dagestan Development Corporation OJSC, Alibekov A.B.
Published: January 2021

АО «Корпорация развития Дагестана» как ведущий институт развития на территории Республики Дагестан пережил полную перезагрузку в конце 2019 года. Начался моментальный процесс выстраивания на базе Корпорации полноценного института развития, в связи с чем была составлена стратегическая дорожная карту по наиболее перспективным направлениям с целью привлечения крупных инвестиционных холдингов на территорию Республики. Одной из приоритетных направлений для развития в регионе Корпорация выбрала возобновляемую энергетику. Возобновляемая энергетика – это ключевой тренд устойчивого развития во всем мире, и Дагестан в этом отношении обладает огромным незадействованным потенциалом. В последние годы в России на базе государственных мер поддержки ВИЭ (возобновляемой энергетики) сформировался ряд крупных компаний с зарубежным участием, которые реализуют проекты в разных регионах, с учетом тех требований, которые прописаны в законодательстве. Но, наверное, самое главное, ВИЭ – это возможность придать импульс к развитию Дагестана в горизонте 2020-2025 гг. Проекты ВИЭ – это инвестиционно ёмкие проекты с большим объемом строительно-монтажных работ, созданием рабочих мест и большим объемом налоговых поступлений. В связи с этим начиная с 2014 года как появился механизм ДПМ регионы активно вовлекают к себе инвесторов, и на данный момент суммарная установленная мощность всех энергообъектов построенных по данному механизму составляет почти 2 ГВт, однако до недавнего времени Дагестан оставался за пределами поля зрения инвесторов. В настоящий момент в данном направлении ведется активная работа по стимулированию развития возобновляемой энергетики в Республике Дагестан и формированию благоприятных условий для привлечения инвестиций в данный сектор. Корпорация развития Дагестана осуществляет полное сопровождение реализации планируемых инвестиционных проектов российских энергетических компаний в области солнечной, ветровой и малой гидроэнергетики в рамках реализации механизма ДПМ ВИЭ на территории Республики Дагестан. По результатам стратегической оценки технического потенциала возобновляемой энергетики Республики Дагестан, Корпорацией были определены ряд перспективных инвестиционных площадок для размещения объектов ВИЭ, что также благоприятно повлияло на систему принятия решения по выбору инвестиционных площадок для инвесторов, с которыми Корпорация подписала соглашение, такие как «Хевел», «Солар Системс», «Нова-Винд» и «Фонд развития Ветроэнергетики».
A MODEL APPROACH TO ESTIMATING AERODYNAMIC CHARACTERISTICS OF THE WIND GENERATOR BLADES
Authors:   Dagestan State University, Rabadanov K.M. , Shakhsinov G.Sh. ,   Dagestan State University
Published: January 2021

В настоящей работе рассмотрены вопросы моделирование сечения лопасти ветро-генератора с использованием пакета программ COMSOL Multiphysics. Проиллюстрированы результаты моделирования сечения лопасти при скорости набегающего ветра 6 м/с. Приведен анализ скорости потока воздуха и давления при различных типах профиля и при различных углах потока ветра.
VANADIUM FLOW BATTERY CELL PERFORMANCE STUDY
Authors:   National Research University ", Fedotov A.A. ,   MEI",   Joint Institute for High Temperatures RAS, Tarasenko A.B. ,   Joint Institute for High Temperatures RAS
Published: January 2021

Индустрия химических источников тока развивается очень быстро, уже сейчас потребность в химических источниках тока нового поколения наблюдается не только в сфере автомобилестроения и портативных устройств, но и сфере возобновляемых источников энергии. Целью данной работы заключалась в создании единичного элемента проточной батарее, в монтаже испытательного стенда и в получении характеристик ванадиевого аккумулятора.
COMBINED ENERGY TECHNOLOGIES, COMBINING RENEWABLE AND HYDROGEN ENERGY
Authors:   INSTITUTE FOR PROBLEMS OF GEOTHERMY AND RENEWABLE ENERGY - BRANCH OF THE JOINT INSTITUTE OF HIGH TEMPERATURES RAS, Idrisov I.M.
Published: January 2021

В статье рассмотрены вопросы целесообразности использования альтернативной электроэнергии возобновляемых источников в сочетании с водородной энергетикой, обоснован выбор водорода в качестве накопителя энергии, способы его получения, приведены расчетные данные для хранения водорода в зависимости от параметров и сравнительные данные накопителей энергии, рассмотрена целесообразность использования водородной энергии при больших потребностях тепловой и электрической энергии и в труднодоступных местах с отсутствием традиционной энергии.
TECHNICAL POTENTIAL OF CROP WASTE AS AN ENERGY RESOURCE FOR AGRICULTURAL AREAS OF DAGESTAN
Authors:   Moscow State University named after M.V. Lomonosov, Andrenko T.I. , Kiseleva S.V. ,   Moscow State University named after M.V. Lomonosov, Rafikova Yu.Yu. ,   Moscow State University named after M.V. Lomonosov
Published: January 2021

Использование древесной биомассы, полученной от обрезков и удаления многолетних сельскохозяйственных насаждений для нужд энергетики, является относительно новым направлением, которое сейчас активно исследуется и развивается в Европе. Опыт европейских стран показывает, что использование отходов выращивания многолетних насаждений для получения энергии может носить коммерческий, экономически выгодный характер. В России садоводство и виноградарство также является традиционным направлением сельского хозяйства в южных регионах, в частности, в Республике Дагестан. Дагестан энергозависимый регион с целым рядом проблем топливно-энергетического комплекса. Решение этих проблем может заключаться в использовании возобновляемых энергоресурсов региона. Дагестан характеризуется развитым сельским хозяйством. Основные направления земледелия в нём – возделывание зерновых культур и плодоводство. Отходы этих производств рассматриваются в этой работе как ресурс для получения тепловой энергии. С этой целью для всех районов республики выполнен расчёт технического теплового потенциала отходов этого типа растениеводства. В программе QGIS проведён анализ пространственного распределения полученных значений потенциала. Сделан вывод, что на севере республики наиболее эффективно использование в качестве энергоресурса отходов зерновых (соломы). Ряд горных, прибрежных и южных районов обладают значительным техническим тепловым потенциалом обрезков древесины плодовых и винограда. Подобный анализ ресурсов различных видов растениеводства, их распределения по территории, а также технологической базы для их переработки в энергетических целях целесообразен и в других сельскохозяйственных регионах с преобладанием сельского населения и наличием экономических и энергетических проблем.
ENERGY SOLUTIONS AND POTENTIAL USE OF RENEWABLE ENERGY SOURCES IN AGRICULTURE OF THE REGION
Authors:   INSTITUTE FOR PROBLEMS OF GEOTHERMY AND RENEWABLE ENERGY - BRANCH OF THE JOINT INSTITUTE OF HIGH TEMPERATURES RAS, Ninalalov S.A. ,   Dagestan State University, Alikerimova T. D. ,   Dagestan State University
Published: January 2021

Энергетическая независимость и производство продуктов питания являются одними из самых больших проблем, стоящих перед миром. Усиливается интерес к технологиям, которые приводят к большей энергетической безопасности в производстве продуктов питания. Разнообразные возобновляемые источники энергии, такие как солнце, ветер, геотермальная энергия, вода и биомасса обеспечивают возможность, используя соответствующие технологии и установки, кормить сельское хозяйство и животноводство чистой энергией даже в местах, не связанных с сетью распределения электроэнергии. Инвестируя в такое решение получают эффект от ряда преимуществ на протяжении десятилетий: меньше электроэнергии, отопления и стоимости топлива; большая рентабельность производства; больше независимости; сокращение отходов и охрана окружающей среды явля-ются частью преимуществ систем возобновляемой энергии для сельского хозяйства. Сельское хозяйство является самым надёжным вложением капитала. Сверхприбыль здесь получить сложно, но и «прогореть» вероятность меньше. Проведенный анализ показал возможность сочетания вариантов бизнеса, например, роботизированные животноводческие комплексы с экологической системой переработки отходов для получения энергии. Такое сочетание во многом определяет развития сельского хозяйства в общем и животноводства в частности. Бизнес-привлекательность преобразовывает тезис о роботизированном энергонезависимом сельском хозяйстве из декларируемой необходимости в вы-годное направление инвестиций.
POSSIBILITIES AND RISKS OF THE USE OF RES IN THE ENERGY SUPPLY OF TOURISM IN THE ARCTIC
Authors:   Moscow State University named after M.V. Lomonosov, Nefedova L.V. , Soloviev D.A. ,   Institute of Oceanology named after P.P. Shirshov Russian Academy of Sciences (IO RAS),
Published: January 2021

Государственные планы по развитию туризма в Арктической зоне РФ (АЗ РФ) требуют решения вопросов энерообеспечения мест размещения. В этой области, а также для привлечения потоков туристов могут использованы возобновляемые источники энергии (ВИЭ). Рассмотрены возможности, перспективы и риски данного вида энергобеспечения в Российской Арктике. Показан российский и зарубежный опыт использования ВИЭ для целей туризма в Арктике. Описаны вопросы необходимости расширения энергетической инфраструктуры и варианты энергоснабжения регионов Российской Арктики. Проведен SWOT анализ перспектив развития распределенной электрогенерации на ВИЭ в Арктическом регионе. Выделены типы финансовых рисков, которые могут возникнуть при проведении проектов возобновляемой энергетики в Арктике.
Uji Aktivitas Repelen Ekstrak Etanol Bunga Marigold (Tagetes erecta) Terhadap Nyamuk Aedes aegypti
Authors: Shinta Mas Arya
Published: January 2021

AbstractAedes aegypti mosquitoes are vectors of dengue fever caused by dengue virus infection. Marigold flower (Tagetes erecta) is a multipurpose plant, marigold flower has a distinctive smell that is widely used as an insect repellent plant. Marigold flower contains a compound of secondary metabolites that potentially have an effect as a natural insecticide. This study was conducted with a complete random draft by taking five treatments, namely: one negative control group (K-), three treatment groups (p1, P2, P3), and one positive control group (K+). The test results portray the marigold flower ethanol extract has a protection power of 0% on K-; 41.67% on P1; 71.67% on P2; 93.3% on P3; and 100% on K+. Screening phytochemicals against marigold flower ethanol extract identifies positive compounds of alkaloids, flavonoids, saponins, tannins, and triterpenoids. The protection power result shows that the marigold power ethanol extract 10% concentration lotion has a potential to have activity as repellent against Aedes aegypti mosquitoes with protection power above 90%.AbstrakNyamuk Aedes aegypti merupakan vektor dari penyakit Demam Berdarah Dengue (DBD) yang disebabkan oleh infeksi virus dengue. Bunga marigold (Tagetes erecta) merupakan tanaman yang multiguna, bunga marigold memiliki bau khas yang menyengat sehingga banyak digunakan sebagai tanaman pengusir serangga. Bunga marigold mengandung senyawa metabolit sekunder yang berpotensi memiliki efek sebagai insektisida alami. Penelitian dilakukan dengan Rancangan Acak Lengkap (RAL) dengan mengambil lima perlakuan, yaitu satu kelompok kontrol negatif (K-), tiga kelompok perlakuan (P1, P2, P3), dan satu kelompok kontrol positif (K+). Hasil pengujian menunjukkan bahwa ekstrak etanol bunga marigold memiliki daya proteksi pada K- sebesar 0%, P1 sebesar 41,67%, P2 sebesar 71,67%, P3 sebesar 93,3%, dan K+ sebesar 100%. Skrining fitokimia terhadap ekstrak etanol bunga marigold mengidentifikasi positif senyawa alkaloid, flavonoid, saponin, tanin, dan triterpenoid. Hasil pengujian daya proteksi menunjukkan bahwa lotion ekstrak etanol bunga marigold konsentrasi 10% berpotensi memiliki aktivitas sebagai repellent terhadap nyamuk Aedes aegypti dengan daya proteksi diatas 90%.
GAMBARAN DOKUMENTASI ASUHAN KEPERAWATAN SPIRITUAL ISLAM BERBASIS KOMPUTER
Authors: Ningsih Dewi Mustika , Siti Aisyah Popy , Rohadatul â€˜Aisy Hasna
Published: January 2021

Dokumentasi asuhan keperawatan spiritual Islam berbasis komputer merupakanpencatatan oleh perawat secara computerized setelah melakukan asuhan keperawatanberupa pemenuhan kebutuhan spiritual pasien selama dirawat di rumah sakit. Penelitianini bertujuan untuk menggambarkan dokumentasi pengkajian, diagnosis, perencanaan,pelaksanaan dan evaluasi keperawatan spiritual Islam berbasis komputer. Jenis penelitianini deskriptif kuantitatif, sampel menggunakan cluster sampling, sebanyak 55 berkasrekam medis pasien. Instrumen penelitian dengan lembar observasi terdiri 17 pernyataanmeliputi aspek pengkajian, diagnosis, perencanaan, pelaksanaan dan evaluasi keperawatanspiritual Islam. Hasil penelitian menunjukkan bahwa dokumentasi asuhan keperawatanspiritual Islam secara komputer untuk dokumentasi pengkajian sebagian besar terisilengkap, dokumentasi diagnosis keperawtan belum ada, dokumentasi perencanaankeperawatan belum ada, dokumentasi pelaksanaan keperawatan setengahnya terisi dandokumentasi evaluasi keperawatan belum ada. Simpulan dalam penelitian ini, bahwadokumentasi pengkajian dan pelaksanaan yang banyak diisi oleh perawat, sedangkandiagnosis perencanaan dan evaluasi belum terdokumentasi dengan baik secara komputer.Rekomendasi agar bidang keperawatan membuat format dokumentasi asuhan keperawatanspiritual Islam lengkap dengan menambahkan kolom diagnosis, perencanaan dan evaluasikeperawatan secara komputer.
PERSEPSI PASIEN TERHADAP PELAYANAN KEPERAWATAN SYARIAH
Authors: Fatmawati Ariani , Rahman Arif , Yualita Perla
Published: January 2021

Implementasi syariah harus dilaksanakan di semua bidang kehidupan, tidak terkecuali di bidang pelayanan keperawatan. Perawat harus menjadikan pelaksanaan keperawatan syariah sebagai sebuah bentuk ibadah sehingga pasien mendapatkan manfaat dari pelayanan syariah yang diberikan. Penelitian ini bertujuan untuk mengetahui persepsi pasien terhadap pelayanan keperawatan syariah di ruang rawat inap Rumah Sakit Al-Islam Bandung. Jenis penelitian ini adalah deskriptif kuantitatif. Sampel pada penelitian ini berjumlah 102 orang yang diambil dengan menggunakan teknik purposive sampling. Pengambilan data dengan menggunakan kuesioner yang terdiri dari 26 pertanyaan dan terbagi kedalam dua subvariabel yaitu persepsi pasien terhadap pelaksanaan pelayanan keperawatan syariah dan persepsi pasien terhadap perilaku Islami. Hasil penelitian ini menunjukkan bahwa lebih dari setengah responden (54%) memiliki persepsi yang baik terhadap pelaksanaan pelayanan syariah. Begitu juga persepsi pasien terhadap perilaku Islami perawat, lebih dari setengah pasien menilai baik (54%). Dengan persepsi pasien yang baik diharapkan kepuasan pasien terhadap pelayanan keperawatan semakin meningkat. Disarankan kepada manajemen rumah sakit untuk terus meningkatkan supervisi terhadap pelaksanaan pelayanan keperawatan syariah dan mendorong agar perawat melakukannya sebagai bagian dari ibadah.
KECEMASAN KELUARGA DALAM MERAWAT KLIEN SKIZOFRENIA
Authors: Hadiansyah Tantan , Pragholapati Andria
Published: January 2021

Data penderita gangguan jiwa berat di wilayah Indonesia sebagian besar berada dimasyarakat dibandingkan di rumah sakit. Perbaikan kondisi skizofrenia sangat terkaitdengan keterlibatan keluarga dalam kehidupan skizofrenia. Keluarga yang merawatanggota keluarga yang dengan skizofrenia mengalami gangguan psikologis penelitianini menggunakan metode deskriptif kuantitatif. Sampel berjumlah 24 responden denganteknik non probability sampling dengan metoda consecutive sampling dengan kriteriaanggota keluarga yang merawat anggota keluarga skizofrenia di Puskesmas Melong AsihKota Cimahi. Instrumen penelitian menggunakan zungâ€™s self-rating anxiety scale. Tingkatkecemasan yang dialami oleh anggota keluarga yang merawat penderita skizofreniasebagian besar responden (79%) berada pada skor kecemasan sedang dan 21% respondenmengalami kecemasan yang berat. kecemasan berat ini dimanifestasikan dengan adanyagangguan terhadap aktivitas sehari-hari pada anggota keluarga yang merawat penderitaskizofrenia. Saran dukungan keluarga diharapkan dapat dimasukan sebagai salah satubagian dari penanganan kecemasan pada anggota keluarga yang merawat anggota keluargaskizofrenia.
PENGARUH SELF MANAGEMENT DIETARY COUNSELLING (SMDC) TERHADAP KUALITAS HIDUP PADA PASIEN HEMODIALISIS
Authors: Hermawati Hermawati , Silvitasari Ika
Published: January 2021

Pasien dengan gagal ginjal membutuhkan diet ketat untuk mempertahankan kualitas hidup. Metode Self Management Dietary Counselling (SMDC). SMDC dibutuhkan untuk meningkatkan pengetahuan pasien dan merubah perilaku menjadi lebih baik untuk menjaga nutrisi tubuh pasien gagal ginjal agar kualitas hidup pasien menjadi lebih baik. Penelitian ini bertujuan untuk mengetahui pengaruh  SMDC  terhadap kualitas hidup pada pasien hemodialisis. Metode penelitian yaitu  pre-test and post-test with control group design (quasi experiment with control). Sampel yang dilibatkan yaitu pasien hemodialisis sebanyak 40 orang. Teknik sampling menggunakan non pobablity sampling dengan pendekatan consecutive sampling. Pengambilan data menggunakan KDQoL SF-36 dan teknik konseling SMDC. Hasil penelitian menunjukkan nilai rata-rata 76,30 (kelompok I) dan 76,05 (kelompok II) yang berarti responden memiliki kemampuan untuk meningkatkan kualitas hidup, dengan nilai p=0,000. Pemberian konseling hendaknya diberikan kepada pasien yang menjalani hemodialisa karena konsep SMDC perlu diterapkan dalam keperawatan untuk menangani pasien-pasien dengan penyakit kronis, seperti diabetes mellitus dan gagal hinjal kronis yang menjalani hemodialisa (Hidayati, 2012). Self Mangement Dietary Counseling (SMDC) dapat meningkatkan  kualitas hidup pada pasien hemodialisis dan diharapkan menjadi rujukan bagi pelayanan kesehatan, institusi pendidikan dan bagi peneliti sehingga dapat meningkatkan kualitas hidup pasien agar tetap stabil.
KARAKTERISTIK PASIEN FRAKTUR EKSTERMITAS BAWAH
Authors: Platini Hesti , Chaidir Rizal , Rahayu Urip
Published: January 2021

Fraktur merupakan salah satu penyebab cacat diantaranya akibat kecelakaan. Fraktur ekstremitas bawah sering terjadi terkait dengan morbiditas yang cukup besar dan meenyebabkan perawatan panjang di rumah sakit. Gangguan akibat fraktur berdampak pada toleransi aktivitas sehingga mengurangi produktivitas. Selama ini karakteristik penderita fraktur ektermitas bawah belum diketahui, sehingga jika tidak dilakukan tidak dapat diketahui pencegahan resiko fraktur. Penelitian ini bertujuan untuk mengetahui karakteristik pasien fraktur ektermitas bawah. Metode penelitian ini merupakan penelitian deskriptif kuantitatif dengan observasional. Tekhnik sampling yang digunakan yaitu total sampling, sehingga didapatkan responden sebanyak 40 orang. Analisa hasil yaitu menggunakan analisis statistik distribusi frekeunsi. Hasil dari penelitian ini yaitu semua responden berjenis kelamin laki-laki (100%), sebagian besar responden berusia 36-45 (42,5%), untuk jenis fraktur sebagian besar yaitu fraktur terbuka sebanyak 25 (62,5%) dan lokasi fraktur terbanyak yaitu pada tibia sebanyak 26 responden (62,5%). Fraktur dapat mempengaruhi produktivitas penderita akibat adanya gangguan ektermitas akibat cedera yang menganggu fungsi tubuh. Dengan mengetahui karakteristik pasien fraktur ektermitas bawah, maka perawat dapat melakukan intervensi keperawatan yang sesuai. Diperlukan penelitian lebih lanjut mengenai faktor resiko yang mempengaruhi fraktur ektermitas bawah yang dikaitkan dengan karakteristik
KONTRIBUSI KUALITAS HIDUP TERHADAP SUCCESSSFULL AGING LANSIA
Authors: Utomo Shella , Prathama Siswadi Ahmad Gimmy , Sriati Aat
Published: January 2021

Penuaan merupakan suatu proses lansia pada tahap perkembangan sehingga lansiamengalami penurunan pada fungsi fisik, psikologis, dan sosial. Perubahan jugamengharuskan lansia untuk mampu beradaptasi atas kemunduran yang dialami. Kualitashidup merupakan salah satu hal yang dibutuhkan untuk mencapai successful aging.Successful aging merupakan kondisi lansia baik secara fisik, psikologis, sosial maupun prosesadaptasi untuk mengoptimalkan kemampuan yang dimiliki akibat proses penuaan. Tujuanpenelitian ini adalah mengidentifikasi kontribusi kualitas hidup terhadap successful aging.Metode penelitian ini kuantitatif dengan pendekatan cross sectional. Populasi penelitianyaitu lansia yang tinggal di BPSTW Ciparay Provinsi Jawa Barat. Teknik pengambilansample purposive sampling dengan jumlah sampel sebanyak 71 orang. Instrumen penelitianmenggunakan OPQOL 13 dan SAS-14. Analisis data dengan uji korelasi menggunakan ujichi square untuk menganalisis kontribusi kualitas hidup terhadap successful aging. Hasilpenelitian menunjukkan jumlah successsful aging dalam kategori tinggi sebanyak 28responden dan kategori rendah sebanyak 43 responden. Kualitas hidup menunjukkanadanya hubungan yang signifikan terhadap successful aging (p<0,05). Kesimpulan penelitianini adalah kualitas hidup yang baik dapat berkontribusi bagi lansia untuk mencapai kondisisuccessful aging, dan dimensi yang paling berkontribusi pada kualitas hidup yaitu aspekmateri, kepuasan hidup, sosial dan psikologis. Adapun, dimensi yang memengaruhi tidaktercapainya successful aging yaitu kesehatan, kemandirian dan hubungan sosial.
PENGARUH TERAPI PIJAT DAN AROMATERAPI MAWAR TERHADAP PENURUNAN NYERI MENSTRUASI PADA REMAJA PUTRI
Authors: Salamun Sri Ayu Arianti , Mentari Mentari
Published: January 2021

Nyeri menstruasi merupakan gangguan yang sering dialami oleh sebagian besarwanita. Kebanyakan wanita mengalami tingkat kram yang bervariasi, dari tingkat nyeriringan sampai nyeri berat. Beberapa remaja putri menderita rasa sakit yang mampumenghentikan aktivitas belajar. Terapi pijat dan aromaterapi merupakan terapi tradisionalyang digunakan sejak zaman dahulu. Penelitian ini bertujuan untuk mengetahui pengaruhterapi pijat dan aromaterapi mawar terhadap penurunan nyeri menstruasi. Desainpenelitian menggunakan Penelitian Analitik dengan Pendekatan Eksperimen. Sampeldalam penelitian 44 orang mahasiswi kebidanan menggunakan Teknik Random Samplingdengan kriteria inklusi remaja putri yang sedang mengalami nyeri menstruasi, belummenikah dan belum mempunyai anak. Data diperoleh dengan cara prates tingkat nyeridengan instrumen skala penilaian, Pada kelompok eksperimen diberikan perlakuan 1 kaliterapi pijat dan aromaterapi mawar selama 30 menit, kemudian dilakukan pascates untukmengetahui penurunan tingkat nyerinya. Analisis statistik menggunakan t-test. Hasilpenelitian menunjukkan bahwa skala nyeri menstruasi pascates lebih rendah dibandingkandengan skala nyeri menstruasi prates pada kelompok perlakuan dengan p-value (0,000),sedangkan pada kelompok kontrol tidak terdapat penurunan yang signifikan pada skalanyeri menstruasi dengan p-value (0,789). Terdapat pengaruh terapi pijat dan aromaterapimawar terhadap penurunan nyeri menstruasi. Hasil dari penelitian ini diharapkan dapatmengimplikasikan terapi untuk pengembangan ilmu kebidanan bagi masyarakat.
PENGARUH JALAN KAKI DUA PULUH MENIT TERHADAP PENURUNAN TEKANAN DARAH PADA PENDERITA HIPERTENSI
Authors: Gartika Nina , Nur Al Idrus Syahida , Wilandika Angga
Published: January 2021

Hipertensi masih menjadi salah satu penyebab kematian di Indonesia sebanyak 70% orangmenderita hipertensi pada tahun 2018. Salah satu penatalaksanaan untuk mengurangiterjadinya komplikasi pada hipertensi yaitu berupa aktivitas fisik jalan kaki. Penelitiantentang pengaruh jalan kaki terhadap penurunan tekanan darah sudah banyak dilakukantetapi khusus pada usia dewasa madya dengan durasi tertentu (20 menit) belum pernahdilakukan. Penelitian ini bertujuan untuk mengetahui adanya pengaruh jalan kaki 20menit terhadap penurunan tekanan darah pada penderita hipertensi. Desain penelitianyang digunakan yaitu kuantitatif dengan jenis quasi experiment without control group preposttest design. Sampel yang terlibat sebanyak 15 orang penderita hipertensi yang diambilsecara consecutive sampling. Analisis inferensial yang digunakan adalah uji statistik t-testdengan tingkat kemaknaan 0,05. Hasil penelitian menunjukkan bahwa sebagian besarresponden berjenis kelamin perempuan (73,3%), berpendidikan SD (46,7%), bekerjasebagai IRT (60,0%), dan memiliki kategori IMT overweight (53,3%). Hasil uji statistikrerata nilai tekanan darah sistolik dan diastolik setelah perlakuan (p-value = 0,000). Dapatdisimpulkan bahwa terdapat pengaruh jalan kaki 20 menit terhadap penurunan tekanandarah. Saran yang dapat diberikan bahwa jalan kaki 20 menit selama tiga kali seminggudapat menjadi pilihan sebagai terapi nonfarmakologi dalam menurunkan tekanan darah
Sustainable City Planning: A Data-Driven Approach for Mitigating Urban Heat
Authors: MacLachlan Andrew , Biggs Eloise , Roberts Gareth , Boruff Bryan
Published: January 2021

Urban areas are expected to triple by 2030 in order to accommodate 60% of the global population. Anthropogenic landscape modifications expand coverage of impervious surfaces inducing the urban heat island (UHI) effect, a critical twenty first century challenge associated with increased economic expenditure, energy consumption, and adverse health impacts. Yet, omission of UHI measures from global climate models and metropolitan planning methodologies precludes effective sustainable development governance. We present an approach that integrates Earth observation and climate data with three-dimensional urban models to determine optimal tree placement (per square meter) within proposed urban developments to enable more effective localized UHI mitigation. Such data-driven planning decisions will enhance the future sustainability of our cities to align with current global urban development agendas.
Pcgf1 Regulates Early Neural Tube Development Through Histone Methylation in Zebrafish
Authors: Li Xinyue , Ji Guangyu , Zhou Juan , Du Jingyi , Li Xian , Shi Wei , Hu Yong , Zhou Wenjuan , Hao Aijun
Published: January 2021

The neural induction constitutes the initial step in the generation of the neural tube. Pcgf1, as one of six Pcgf paralogs, is a maternally expressed gene, but its role and mechanism in early neural induction during neural tube development have not yet been explored. In this study, we found that zebrafish embryos exhibited a small head and reduced or even absence of telencephalon after inhibiting the expression of Pcgf1. Moreover, the neural induction process of zebrafish embryos was abnormally activated, and the subsequent NSC self-renewal was inhibited after injecting the Pcgf1 MO. The results of in vitro also showed that knockdown of Pcgf1 increased the expression levels of the neural markers Pax6, Pou3f1, and Zfp521, but decreased the expression levels of the pluripotent markers Oct4, Hes1, and Nanog, which further confirmed that Pcgf1 was indispensable for maintaining the pluripotency of P19 cells. To gain a better understanding of the role of Pcgf1 in early development, we analyzed mRNA profiles from Pcgf1-deficient P19 cells using RNA-seq. We found that the differentially expressed genes were enriched in many functional categories, which related to the development phenotype, and knockdown of Pcgf1 increased the expression of histone demethylases. Finally, our results showed that Pcgf1 loss-of-function decreased the levels of transcriptional repression mark H3K27me3 at the promoters of Ngn1 and Otx2, and the levels of transcriptional activation mark H3K4me3 at the promoters of Pou5f3 and Nanog. Together, our findings reveal that Pcgf1 might function as both a facilitator for pluripotent maintenance and a repressor for neural induction.
Microclusters as T Cell Signaling Hubs: Structure, Kinetics, and Regulation
Authors: Balagopalan Lakshmi , Raychaudhuri Kumarkrishna , Samelson Lawrence E.
Published: January 2021

When T cell receptors (TCRs) engage with stimulatory ligands, one of the first microscopically visible events is the formation of microclusters at the site of T cell activation. Since the discovery of these structures almost 20 years ago, they have been studied extensively in live cells using confocal and total internal reflection fluorescence (TIRF) microscopy. However, due to limits in image resolution and acquisition speed, the spatial relationships of signaling components within microclusters, the kinetics of their assembly and disassembly, and the role of vesicular trafficking in microcluster formation and maintenance were not finely characterized. In this review, we will summarize how new microscopy techniques have revealed novel insights into the assembly of these structures. The sub-diffraction organization of microclusters as well as the finely dissected kinetics of recruitment and disassociation of molecules from microclusters will be discussed. The role of cell surface molecules in microcluster formation and the kinetics of molecular recruitment via intracellular vesicular trafficking to microclusters is described. Finally, the role of post-translational modifications such as ubiquitination in the downregulation of cell surface signaling molecules is also discussed. These results will be related to the role of these structures and processes in T cell activation.
Dynamic Expression of m6A Regulators During Multiple Human Tissue Development and Cancers
Authors: Zhang Ya , Xu Sicong , Xu Gang , Gao Yueying , Li Si , Zhang Ke , Tian Zhanyu , Guo Jing , Li Xia , Xu Juan , Li Yongsheng
Published: January 2021

N6-methyladenosine (m6A) plays critical roles in human development and cancer progression. However, our knowledge regarding the dynamic expression of m6A regulators during human tissue development is still lacking. Here, we comprehensively analyzed the dynamic expression alterations of m6A regulators during seven tissue development and eight cancer types. We found that m6A regulators globally exhibited decreased expression during development. In addition, IGF2BP1/2/3 (insulinlike growth factor 2 MRNA-binding protein 1/2/3) exhibited reverse expression pattern in cancer progression, suggesting an oncofetal reprogramming in cancer. The expressions of IGF2BP1/2/3 were regulated by genome alterations, particularly copy number amplification in cancer. Clinical association analysis revealed that higher expressions of IGF2BP1/2/3 were associated with worse survival of cancer patients. Finally, we found that genes significantly correlated with IGF2BP1/2/3 were significantly enriched in cancer hallmark-related pathways. In summary, dynamic expression analysis will guide both mechanistic and therapeutic roles of m6A regulators during tissue development and cancer progression.
Cutaneous Malassezia: Commensal, Pathogen, or Protector?
Authors: Vijaya Chandra Shree Harsha , Srinivas Ramasamy , Dawson Thomas L. , Common John E.
Published: January 2021

The skin microbial community is a multifunctional ecosystem aiding prevention of infections from transient pathogens, maintenance of host immune homeostasis, and skin health. A better understanding of the complex milieu of microbe-microbe and host-microbe interactions will be required to define the ecosystem’s optimal function and enable rational design of microbiome targeted interventions.Malassezia, a fungal genus currently comprising 18 species and numerous functionally distinct strains, are lipid-dependent basidiomycetous yeasts and integral components of the skin microbiome. The high proportion ofMalasseziain the skin microbiome makes understanding their role in healthy and diseased skin crucial to development of functional skin health knowledge and understanding of normal, healthy skin homeostasis. Over the last decade, new tools forMalasseziaculture, detection, and genetic manipulation have revealed not only the ubiquity ofMalasseziaon skin but new pathogenic roles in seborrheic dermatitis, psoriasis, Crohn’s disease, and pancreatic ductal carcinoma. Application of these tools continues to peel back the layers ofMalassezia/skin interactions, including clear examples of pathogenicity, commensalism, and potential protective or beneficial activities creating mutualism. Our increased understanding of host- and microbe-specific interactions should lead to identification of key factors that maintain skin in a state of healthy mutualism or, in turn, initiate pathogenic changes. These approaches are leading toward development of new therapeutic targets and treatment options. This review discusses recent developments that have expanded our understanding ofMalassezia’s role in the skin microbiome, with a focus on its multiple roles in health and disease as commensal, pathogen, and protector.
Proximity-Based Compression for Network Embedding
Authors: Islam Muhammad Ifte , Tanvir Farhan , Johnson Ginger , Akbas Esra , Aktas Mehmet Emin
Published: January 2021

Network embedding that encodes structural information of graphs into a low-dimensional vector space has been proven to be essential for network analysis applications, including node classification and community detection. Although recent methods show promising performance for various applications, graph embedding still has some challenges; either the huge size of graphs may hinder a direct application of the existing network embedding method to them, or they suffer compromises in accuracy from locality and noise. In this paper, we propose a novelNetworkEmbedding method, NECL, to generate embedding more efficiently or effectively. Our goal is to answer the following two questions: 1) Does the networkCompression significantly boostLearning? 2) Does network compression improve the quality of the representation? For these goals, first, we propose a novel graph compression method based on the neighborhood similarity that compresses the input graph to a smaller graph with incorporating local proximity of its vertices into super-nodes; second, we employ the compressed graph for network embedding instead of the original large graph to bring down the embedding cost and also to capture the global structure of the original graph; third, we refine the embeddings from the compressed graph to the original graph. NECL is a general meta-strategy that improves the efficiency and effectiveness of many state-of-the-art graph embedding algorithms based on node proximity, including DeepWalk, Node2vec, and LINE. Extensive experiments validate the efficiency and effectiveness of our method, which decreases embedding time and improves classification accuracy as evaluated on single and multi-label classification tasks with large real-world graphs.
Geomorphological Evidence of Active Faulting in Low Seismicity Regions—Examples From the Valley of Gobi Lakes, Southern Mongolia
Authors: van der Wal Jorien L. N. , Nottebaum V. C. , Stauch G. , Binnie S. A. , Batkhishig O. , Lehmkuhl F. , Reicherter K.
Published: January 2021

Active intraplate deformation as a far-field effect of the India-Eurasia convergence has led to four Mw∼8 earthquakes in western and southern Mongolia in the past century. Palaeoseismological and morphotectonic studies have shown that these earthquakes are characteristic events along transpressive fault systems with cumulative offsets. The tectonically active Gobi Altai and Hangay mountains are separated by the seismically quiescent Valley of Gobi Lakes, which consists of major perennial rivers draining into endorheic lakes. Despite the scarcity of recorded earthquakes, Quaternary deposits in the Valley of Gobi Lakes are crosscut by multiple fault scarps with significant, landscape-altering displacements. To assess past earthquakes and the potential seismic hazard of this area, we apply remote sensing, tectono-morphometric techniques and cosmogenic nuclide dating to estimate the amount of deformation the faults in the Valley of Gobi Lakes are accommodating, and to determine the effect of these faults on local landscape evolution. The Tuyn Gol (gol = Mongolian for river) is crosscut by four E-W to NE-SW trending fault scarps that display variable fault kinematics due to scarp orientation differences relative to a stable NE-SW principle stress direction. Mapping of the >40–90 km long Valley of Gobi Lake faults shows that they can accommodate M ∼ 7 earthquakes. Offset measurements of the Tuyn Gol deposits allow Middle Pleistocene to modern vertical slip rate estimates and M ∼ 7 earthquake recurrence intervals of 0.012 ± 0.007–0.13 ± 0.07 mm/yr and 5.24 ± 2.61–81.57 ± 46.05 kyr, respectively. Cumulative vertical displacement amounts to 0.27 ± 0.08 mm/yr, which is similar to that of major tectonic structures such as the Bogd fault in the Gobi Altai. This implies that the total active deformation accommodated by southern Mongolian faults may be larger than previously expected and distributed across more faults between the Hangay and the (Gobi) Altai mountain ranges. Geomorphological observations and surface exposure dating indicate that the Tuyn Gol drainage system developed over four to five 100 kyr climate cycles, during which active deformation played an important role in drainage reorganization. Our results demonstrate the dominant role of tectonics on local landscape dynamics, indicating the importance of studying regional geomorphology to adequately estimate the earthquake potential of faults that were considered inactive.
Male Infertility Diagnosis: Improvement of Genetic Analysis Performance by the Introduction of Pre-Diagnostic Genes in a Next-Generation Sequencing Custom-Made Panel
Authors: Precone Vincenza , Cannarella Rossella , Paolacci Stefano , Busetto Gian Maria , Beccari Tommaso , Stuppia Liborio , Tonini Gerolamo , Zulian Alessandra , Marceddu Giuseppe , Calogero Aldo E. , Bertelli Matteo
Published: January 2021

Background

Infertility affects about 7% of the general male population. The underlying cause of male infertility is undefined in about 50% of cases (idiopathic infertility). The number of genes involved in human spermatogenesis is over two thousand. Therefore, it is essential to analyze a large number of genes that may be involved in male infertility. This study aimed to test idiopathic male infertile patients negative for a validated panel of “diagnostic” genes, for a wide panel of genes that we have defined as “pre-diagnostic.”

Methods

We developed a next-generation sequencing (NGS) gene panel including 65 pre-diagnostic genes that were used in 12 patients who were negative to a diagnostic genetic test for male infertility disorders, including primary spermatogenic failure and central hypogonadism, consisting of 110 genes.

Results

After NGS sequencing, variants in pre-diagnostic genes were identified in 10/12 patients who were negative to a diagnostic test for primary spermatogenic failure (n = 9) or central hypogonadism (n = 1) due to mutations of single genes. Two pathogenic variants of DNAH5 and CFTR genes and three uncertain significance variants of DNAI1, DNAH11, and CCDC40 genes were found. Moreover, three variants with high impact were found in AMELY, CATSPER 2, and ADCY10 genes.

Conclusion

This study suggests that searching for pre-diagnostic genes may be of relevance to find the cause of infertility in patients with apparently idiopathic primary spermatogenic failure due to mutations of single genes and central hypogonadism.
Selenium in the Treatment of Graves’ Hyperthyroidism and Eye Disease
Authors: Lanzolla Giulia , Marinò Michele , Marcocci Claudio
Published: January 2021

Based on the role of oxidative stress in the pathogenesis of Graves’ hyperthyroidism (GH) and Graves’ Orbitopathy (GO), a therapy with the antioxidant agent selenium has been proposed and a number of studies have been performed, both in vitro and in vivo. In GH, reactive oxygen species (ROS) contribute to the thyroid and peripheral tissues damage. In GO, tissue hypoxia, as well as ROS, are involved in the typical changes that occur in fibroadipose orbital tissue and the perimysium of extraocular muscles. Antioxidants have been proposed to improve the effects of antithyroid drugs in GH patients, as well as the remodeling of orbital tissues in patients with GO. Here, we reviewed the literature on the possible beneficial effects and clinical use of selenium in the management of patients with GH and GO. A randomized clinical trial on the use of selenium in patients with mild GO provided evidence for a beneficial effect; no data are available on more severe forms of GO. Although the real effectiveness of selenium in patients with GH remains questionable, its use in the management of mild GO is generally believed to be beneficial, and selenium administration has been included in the clinical practice for the patients with mild eye disease.
Effect and Relationship of Seasons on the High Risk of Ovarian Hyperstimulation Syndrome After Oocyte Retrieval in Patients With Polycystic Ovary Syndrome
Authors: Cao Yurong , Shi Hao , Ma Yue , Ma Linna , Zhai Jun
Published: January 2021

Objective

To investigate the effect of seasons on the incidence of high risk of ovarian hyperstimulation syndrome (OHSS) after in oocyte retrieval in patients with polycystic ovarian syndrome (PCOS) and to establish a nomogram to predict the risk of OHSS.

Design

Single-center, retrospective study.

Setting

University-affiliated reproductive medicine center.

Patient(s)

A total of 2,030 infertility patients with PCOS underwent the follicular phase long-acting long protocol IVF/ICSI in the reproductive medicine center from January 2017 to December 2019.

Intervention(s)

None.

Main outcome measure(s)

Logistic regression analysis was used to analyze the factors associated with a high risk of OHSS. We established a nomogram to predict the risk of OHSS in infertility patients with PCOS after oocyte retrieval.

Result(s)

The incidence of patients at high risk of OHSS was significantly different from season-to-season and was especially higher in the summer and winter. Multivariate logistic analysis showed that gonadotropin dosage, number of retrieved oocytes, estradiol level, average bilateral ovarian diameter on the day human chorionic gonadotropin was administered, type of infertility, and average temperature were independent risk factors for OHSS after oocyte retrieval in PCOS patients. Based on the above independent risk factors, we constructed a prediction model for OHSS risk. To evaluate the efficiency of the prediction model, we calculated the C-index (0.849), area under the receiver operating characteristic curve (0.849), and internal validation C-index (0.846). Decision curve analysis suggested that the prediction model exhibited significant net benefits.

Conclusion(s)

The incidence of PCOS patients at high risk for OHSS after oocyte retrieval fluctuated with seasonal temperature changes, and was significantly higher in extreme climates. The prediction model had favorable predictive performance and clinical application value.