bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Social Media Marketing terhadap Brand Awareness, Brand Image dan Brand Loyalty Pesona Indonesia
Authors: Swimbawa Made Krisnantha , M. Lemy Diena
Published: February 2024

This research aims to investigate the influence of Social Media Marketing (SMM) on Brand Awareness, Brand Image and Brand Loyalty of Pesona Indonesia. Quantitative methods with regression analysis were used to analyze data obtained from respondents involved in the use of social media related to Pesona Indonesia. Data collection was carried out through questionnaires distributed online to respondents who had interacted with Pesona Indonesia content on various social media platforms. The independent variables in this research are marketing activities on social media such as the number of posts, interactions and type of content shared. Meanwhile, the dependent variable consists of Brand Awareness, Brand Image, and Brand Loyalty which are measured through questions related to the respondents' awareness, perception, and level of loyalty to the Pesona Indonesia brand. The results of the regression analysis show that there is a significant positive influence between the use of Social Media Marketing and Brand Awareness, Brand Image and Brand Loyalty of Pesona Indonesia. It was found that the more active Pesona Indonesia was in interacting and sharing content on social media, the higher the level of consumer awareness, perception and loyalty towards the brand. This research provides an important contribution in understanding the role of Social Media Marketing in influencing brand image, awareness and consumer loyalty towards Pesona Indonesia. The practical implications of this research can help brand managers to plan more effective marketing strategies on social media platforms to increase consumer awareness, image and loyalty to the Pesona Indonesia brand.

Keywords: Social Media Marketing, Brand Awareness, Brand Image, Brand Loyalty
Pengaruh Kualitas Layanan terhadap Kepuasan Pasien dan Citra Institusi pada Rsud Kabupaten Wakatobi
Authors: Muhammad Syafaruddin La Ode , Daulani Ahmad
Published: February 2024

The objectives of this research are: 1) Testing the influence of service quality on patient satisfaction at the Wakatobi District Hospital; 2) Testing the influence of patient satisfaction on the image of the institution at the Wakatobi District Hospital; 3) Testing the influence of service quality on the image of the institution at the Wakatobi Regency Regional Hospital; 4) Testing the influence of Patient Satisfaction as an intervening variable on Service Quality and Institutional Image at Wakatobi District Hospital. The population in this study were patients and families of patients at the Wakatobi District Hospital. The sample taken was determined to be 68 people. The sampling method used is purposive random sample, namely a sample selection technique based on certain criteria. The data collection technique used was a questionnaire. Data analysis techniques use descriptive analysis, validity testing, reliability testing, hypothesis testing and direct and indirect influence testing using the Structural Equation Modeling (SEM) concept with the Smart PLS (Partial Least Square) program. The result showed that: 1) Service quality has a significant positive effect on patient satisfaction at the Wakatobi district hospital, showing the original sample estimate value between the influence of service quality on satisfaction of 0.742 and a positive value. 2) Patient satisfaction has a significant positive effect on the image of the institution at the Wakatobi District Hospital. 3) Service quality has a significant positive effect on the image of the institution at the Wakatobi District Hospital. The calculated T-value of 1.727 is greater than the T-table of 1.668. 4) Patient Satisfaction as an intervening variable has a dominant influence on Service Quality and Institutional Image at the Wakatobi District Regional Hospital.

Keywords: Learning Herbal Drink, Community Service, Community Business Opportunities
Peran Farmasi Klinis dalam Meningkatkan Keamanan Penggunaan Obat pada Pasien Geriatri : Tinjauan Literatur
Authors: Hapsari Estuningtyas Ayu , Al Farisi Taufiq , Aprilia Sinta Riska
Published: February 2024

With the aging population increasing worldwide, attention to the safety of drug use in geriatric patients is becoming increasingly important. Through a better understanding of the role of clinical pharmacy in this context, it is hoped that more effective strategies can be found to improve the quality of drug care for the geriatric population, thereby providing maximum benefits for patients' health and quality of life. Thus, the aim of this literature observation is to dig deeper into the role of clinical pharmacy in improving the safety of drug use in geriatric patients (Javier, 2023). The aim of exploring relevant literature, we can innovate approaches that have been proven effective, as well as identify challenges and opportunities in optimizing the role of clinical pharmacy in the care of geriatric patients (Annisa, 2012), adjusting doses based on physiological factors related to age, and providing education to patients and families about the correct use of drugs (Sari, 2015). Literature studies suggest that clinical pharmacy interventions, such as thorough medication review, drug counseling, and identification of potential drug interactions, can reduce the risk of side effects and increase patient compliance with drug therapy. Apart from that, health team collaboration between clinical pharmacists, doctors and nurses is also an important factor in ensuring the safe use of drugs in geriatric patients (Karnova, 2020).

Keywords: Clinical Pharmacy, Safety of Drug Use, Geriatric Patients, Literature Review.
Pelatihan Pembuatan Minuman Jawor (Jahe Wortel) sebagai Peluang Usaha Masyarakat di Desa Ciberuem Kecamatan Cisarua Bogor
Authors: Sari Wardhani Hilda , Ardi Noegraha Rosandi , Sari Harsanti Pradnya , Farrah Farrah
Published: February 2024

The purpose of this research is to provide training on innovations in making drinks from carrots to the people of Cibeureum village, Cisarua - Bogor. The method used ABCD (Asset Based Community) to maximize the potential assets, which includes individual assets, communities, infrastructure, community, et al. The the activity of making Jawor Drink (Ginger Carrot) as a business opportunity for the community in Ciberuem Village, Cisarua District, Bogor, is a training method. Pertiwi University Tourism students as instructors provide ideas and also training to the community to turn agricultural products into business opportunities that can help economic development. The people of Cibeureum village are very enthusiastic about the new innovation developed by Pertiwi University students regarding drinks made from carrots. Jawor drink is believed to be a new drink innovation that can be enjoyed in Cibeureum village which has cool weather qualities.

Keywords: Learning Herbal Drink, Community Service, Community Business Opportunities
Strategy of Islamic Religious Instructors in Religious Development of the Da'wah Village Community at Punggur District
Authors: Susilowati Indah , Mukmin Hasan , Rosidi Rosidi , Nopryana Rahmah Dwi
Published: February 2024

Islamic religious counselors generally engage in oral preaching. However, the needs of the community are not limited to intellectual and spiritual aspects alone, thus requiring a developmental strategy in the form of actions or initiatives. This research discusses the strategies employed by Islamic religious counselors in empowering the community of Kampung Dakwah in the Punggur District of Central Lampung Regency. The study aims to analyze the strategies of Islamic religious counselors, identify challenges, and examine the outcomes achieved through the implementation of the strategies used by Islamic religious counselors in empowering the community in Kampung Dakwah. This research is qualitative in nature and employs observation, interviews, and documentation as methods of data collection. The data sources are divided into two categories: primary data sources and secondary data sources, which will be analyzed using data triangulation and conclusion drawing methods. The findings of this research indicate that: (1) The strategies employed by Islamic Religious Counselors in community empowerment in Kampung Dakwah are carried out through stages of awareness raising, transformation of intellectual improvement, and strategy evaluation. (2) The challenges faced include the limited capability of religious counselors in the field of economic empowerment. (3) The outcomes achieved include the reduction of social issues, improved economic conditions for productive-aged poor families, and a decrease in illiteracy rates in reading the Quran in Kampung Dakwah.

Keywords: Strategy of Islamic Religious Instructors. Religious Counselor, Community Development
The Impact of Project-Based Learning Models on Improving Students' Value and Understanding on Natural Sciences Lessons
Authors: Maryani Dwi , Yunianto Aan , Murtiyasa Budi , Masduki Masduki
Published: February 2024

In the era of independent learning, there was a low interest in and understanding of Natural Sciences (IPA) subjects among students. The project-based learning model emerged as an alternative to overcoming these constraints. So researchers want to know the impact of project-based learning in primary schools. The method used is pre-experimental quantitative, with the design as follows: taking samples, pretest, providing guidance, post-test after guidance, looking for the average value of the pretest and post-test, and T test results. The research was conducted at Surakarta Basic School with a 30th grade student. Types of bound variables are the values and understanding of students in the V class of Natural Sciences (IPA) and project-based free learning variables. Collecting techniques with post-test and post-test as well as data analysis with pairs of T tests. Research finds that project-based learning models have an influence on elementary school students in the fifth grade in natural science subjects (IPA). Based on the analysis, results show that t hitung > t table (2.977 > 1.6991) means there are significant differences, so the project-based learning model has an influence on value and understanding.

Keywords: Impact of Project-Based Learning, Project-Based Learning Models, Improving Students' Value
PERANCANGAN SISTEM INFORMASI PEMESANAN UNTUK MENINGKATKAN EFISIENSI OPERASIONAL DI PT.SUPERFOOD CITA INSANI
Authors: Andina Hikmah Fadilah , Edo Arribe  , Hanif Luthfie
Published: February 2024

PT.Superfood Cita Insani adalah perusahaan yang memproduksi dan mendistribusikan produk UMKM. Superfood menjual produk yang sudah lulus uji coba rasa dan cara produksi yang sesuai dengan standar dan ketahanan pangan yang diatur dan ditetapkan oleh Depkes. Proses transaksi penjualan produk pada PT.Superfood Cita Insani masih dilakukan secara konvensional. Hal ini membuat perusahaan kesulitan menjangkau pelanggan. Dapat dikatakan bahwa PT.Superfood Cita Insani memerlukan sistem yang dapat digunakan untuk mempermudah proses transaksi dengan pelanggan, sekaligus dapat memperkenalkan usaha dengan lebih luas. Penelitian ini betujuan untuk membuat sistem informasi pemesanan yang dapat diakses dengan internet melalui website. Metode waterfall digunakan sebagai metode pengembangan sistem ini. Dengan menggunakan waterfall sebagai metode pengambangan, sistem dirancang secara bertahap sesuai urutannya. Dimulai dari analisis, desain, implementasi, pengujian, penerapan hingga pemeliharaan sistem. Sistem informasi pemesanan seperti ini akan memudahkan pelanggan untuk memesan produk tanpa harus pergi ke toko. Selain itu juga perusahaan dapat memasarkan produk lebih luas.
APLIKASI PANDUAN UNTUK MENGENAL TANAMAN OBAT BERBENTUK RIMPANG BERBASIS IMAGE PROCESSING MENGGUNAKAN METODE VGG16
Authors: Aldi Budi Rianta  , Dwi Intan Af'idah  , Ardi Susanto
Published: February 2024

Keanekaragaman hayati Indonesia, khususnya dalam tanaman obat berbentuk rimpang, menjadi fokus penelitian ini. Dengan luas wilayah dan kondisi geografis yang beragam, Indonesia menyimpan kekayaan spesies tanaman obat tradisional. Penelitian terdahulu menunjukkan adanya keterbatasan dalam pengenalan tanaman secara manual, memicu kebutuhan akan teknologi untuk mendukung identifikasi tanaman. Penelitian ini mengembangkan aplikasi panduan berbasis image processing dengan metode VGG16 untuk mengenali tanaman obat berbentuk rimpang. Tahap metodologi melibatkan pengumpulan dataset, praproses citra, implementasi VGG16, evaluasi model dengan confusion matrix, dan pengembangan aplikasi. Pengujian aplikasi menggunakan black box testing menunjukkan keberhasilan dalam identifikasi tanaman, responsivitas antarmuka, dan keamanan data. Hasil analisis citra dan pengembangan aplikasi menunjukkan performa yang optimal. Dengan demikian, aplikasi ini dapat dianggap berhasil dalam mendukung pengenalan tanaman obat berbentuk rimpang.
PENGEMBANGAN APLIKASI PEMANDU WISATA GUCI BERBASIS MOBILE MELALUI PRINSIP USER-CENTERED DESIGN (UCD)
Authors: Muhammad Fikri Hidayattullah  , Dwi Intan Af’idah  , Sharfina Febbi Handayani  , Putri Ajeng Imamah
Published: February 2024

Pariwisata memainkan peran krusial dalam ekonomi Indonesia, dengan pertumbuhan sektor ini mencapai 7,2% per tahun, melebihi rata-rata dunia sebesar 4,7%. Objek Wisata Guci di Kabupaten Tegal, Jawa Tengah, menarik perhatian sebagai destinasi potensial. Namun, kesulitan wisatawan dalam mendapatkan informasi fasilitas umum di tempat tersebut menjadi tantangan. Penelitian ini mengembangkan aplikasi pemandu wisata "Guci Explore" berbasis Android, menerapkan metode User-Centered Design (UCD) untuk meningkatkan pengalaman pengguna. Dengan melibatkan pemandu wisata digital, aplikasi ini memberikan informasi akurat dan terkini untuk mengatasi kebingungan wisatawan. Pengujian menunjukkan kepuasan pengguna mencapai skor 81, memperkuat kategori Grade Scale "A" dan Acceptability Ranges "Acceptable". Aplikasi ini diharapkan dapat meningkatkan efisiensi perjalanan, memberikan manfaat ekonomi lokal, dan mendukung pertumbuhan sektor pariwisata Indonesia.
OPTIMALISASI FILE RAW PADA GAMBAR BACKLIGHT DENGAN MENERAPKAN TEKNIK EDITING HIGH DYNAMIC RANGE (HDR)
Authors: Dhimas Adi Satria Dhimas , Hadi Purwanto Ibnu , Asti Astuti Ika
Published: February 2024

File RAW merupakan salah satu file yang dihasilkan oleh kamera digital selain file JPG atau HEIF, File RAW memiliki data bit pixel yang lebih tinggi dari JPG. Data bit tersebut digunakan untuk melakukan pengolahan gambar dari segi pencahayaan dan pewarnaan.Dalam Fotografi, Gambar Backlight merupakan visualisasi bentuk foto yang mengarahkan pencahayaan langsung mengarah ke kamera, pada kasus ini umumnya didapatkan gambar dengan pencahayaan shadow dan highlight yang tidak merata. Pada penelitian ini, akan dilakukan pengujian untuk mengoptimalkan kemampuan file RAW dalam menghasilkan file HDR dalam studi kasus gambar backlight. Pengujian akan dilakukan dengan metode eksplorasi dengan pengambil banyak sample gambar fotografi backlight, dan melakukan pengolahan file RAW menggunakan berbagai perangkat lunak dari berbagai platform, sehingga akan menghasilkan parameter dalam mengoptimasi file RAW tersebut.

Kata Kunci : High Dynamic Range; RAW; Gambar; Backlight; Kamera
ANALISIS PEMBAYARAN DIGITAL DANA DENGAN APLIKASI ISO/IEC 9126 MODEL BERDASARKAN FAKTOR KEGUNAAN
Authors: Kurniawan Oky , Richky Faizal Amir  , Andreyestha Andreyestha , Taufik Andi , Akbar Fajar , Nawawi Imam
Published: February 2024

Pembayaran digital sudah menjadi tren untuk saat ini. Kemudahan penggunaan aplikasi dan biaya transaksi yang relatif murah telah mengubah pola perilaku masyarakat dalam melakukan pembayaran dan transaksi yang serba digital. Dana merupakan aplikasi dompet digital yang juga berfungsi sebagai pembayaran digital. Banyaknya pesaing saat ini khususnya di bidang pembayaran digital memerlukan adanya evaluasi terhadap kualitas perangkat lunak. Salah satu metode yang digunakan untuk mengukur kualitas perangkat lunak adalah ISO/IEC 9126, sebuah organisasi standardisasi internasional yang digunakan sebagai pedoman model kualitas. Dalam proses evaluasi Usability pada ISO/IEC 9126 terdapat karakteristik kualitas Usability yang meliputi sub-karakteristik kualitas yaitu: keterpahaman, kemampuan belajar, pengoperasian, dan daya tarik. Pengendalian kualitas perangkat lunak yang akan dievaluasi difokuskan pada perspektif Usability dengan tujuan untuk memuaskan kebutuhan pengguna. Nilai dikelompokkan berdasarkan tiga kategori, dari 0-100% tidak memuaskan antara 0%-40%, marginal antara 40%-60%, dan memuaskan antara 60%-100%. Dari hasil perhitungan nilai Usability sebesar 0,84 maka dapat dikatakan kategori memuaskan (satisfactory).
APLIKASI KAMUS BAHASA DAERAH TOLAKI BERBASIS ANDROID
Authors: Anuggrah Yuandi Intan
Published: February 2024

Perkembangan dunia teknologi di era 4.0 saat ini semakin maju, teknologi banyak digunakan oleh pihak atau lembaga pendidikan untuk meningkatkan kecerdasan setiap individu. Kurangnya minat siswa dalam mempelajari bahasa daeah Tolaki menjadikan landasan dasar pada penelitian ini. Kamus Bahasa daerah Tolaki ini merupakan media pembelajaran yang dikemas melalui sistem berbasis android untuk memudahkan siswa(i) untuk belajar dan memahami arti kata Bahasa Daerah Tolaki. Metode waterfall dipilih sebagai metode penelitian dikarenakan memiliki tahapan dan penyusunan yang terstruktur dari tahap analisis kebutuhan hingga pelaporan hasil penelitian. Hasil dari penelitian ini menunjukkan bahwa siswa di SD Negeri 1 Windubite dapat menggunakan aplikasi kamus bahasa Daerah Tolaki dengan mudah, melalui aplikasi ini siswa juga dapat dengan cepat mengetahui arti Bahasa Indonesia yang dikonfersi dalam bahasa Tolaki.
RANCANG BANGUN APLIKASI MOBILE BERBASIS ANDROID UNTUK MANAJEMEN PERSEDIAAN BARANG DAN KASIR
Authors: Syahib Muhammad Irwan
Published: February 2024

Perkembangan teknologi dalam konteks bisnis, teknologi informasi telah mengubah sistem kerja dan memberikan dampak yang segnifikan. Pengguna teknologi informasi memiliki kemampuan untuk mengolah data dengan efisien, sehingga mengoptimalkan produktivitas dalam berbagai industri. Peran teknologi informasi dalam menghasilkan informasi yang cepat dan akurat sangat relevan dalam lingkup usaha yang melibatkan pengolahan data. Sehubungan sistem yang berjalan di UD. Mandiri sudah terkomputerisasi namun dari segi perangkat keras yang di gunakan sekarang sangat tidak evesien di kelistriakan, ukuran prangkat, dan harga prangkat keras. Penulis mengajukan penelitian pengembangan aplikasi dari dekstop ke android di karenakan mengikuti perkembangan teklonogi yang saat ini banyak mengguanakan android yang lebih simple. Penelitian ini mengguanakan metode pengembangan waterfall dalam membangun sebuah aplikasi berbasis Android. Hasil dari penelitian ini dapat membuat aplikasi yang dapat mempermudah proses pendataan barang dan proses transaksi penjualan di UD. Mandiri berbasisi android.
OPTIMALISASI MANAJEMEN PEGAWAI DAN SISTEM INFORMASI BERBASIS WEB DENGAN MENGGUNAKAN DATABASE MYSQL (STUDI KASUS PT. XYZ)
Authors: Waruwu Jurisman , Ofelius Laia  , Yusmei Paskah Harefa  , Abdul Majid Tanjung  , Michael Laowo
Published: February 2024

Optimalisasi manajemen pegawai dan sistem informasi yang diimplementasikan pada sistem manajemen pegawai pada PT. XYZ memberikan dampak positif terhadap efektivitas operasional. Dengan penerapan metode waterfall pada perancangan sistem yang diusulkan pimpinan perusahaan dapat dengan cepat melakukan pengambilan keputusan yang lebih akurat terhadap perubahan kebutuhan perusahaan. Selain itu pimpinan perusahaan mudah memantau status dan aktifitas pegawai pada PT. XYZ.
PEMBANGUNAN INFRASTRUKTUR JARINGAN FIBER OPTIC JALUR UDARA PT. WISUANDHA NETWORK GLOBALINDO DI KABUPATEN BULELENG
Authors: Purbodiningrat RA Enten Rahindrasti , I Nyoman Yudi Anggara Wijaya  , I Gede Juliana Eka Putra
Published: February 2024

Dalam menghadapi pertumbuhan internet yang pesat di Bali, PT Wisuandha Network Globalindo memandang perlunya membangun infrastruktur jaringan fiber optic sendiri sebagai langkah strategis untuk mengatasi tuntutan bandwidth yang semakin tinggi dan meningkatkan kestabilan jaringan. Sebagai perusahaan penyedia jasa internet yang berkomitmen, mereka mengambil inisiatif untuk mengajukan perizinan pembangunan infrastruktur jaringan fiber optic dengan jalur udara.  Untuk mencapai tujuan proyek, PT Wisuandha Network Globalindo akan melibatkan semua pihak terkait, mematuhi regulasi yang berlaku, dan memastikan keandalan serta keamanan infrastruktur yang dibangun. Dengan memanfaatkan skema perizinan yang telah diterapkan di Kabupaten Buleleng, diharapkan proyek ini dapat meningkatkan akses internet yang handal, memperkuat konektivitas, dan mendukung pertumbuhan teknologi informasi di Bali. Fokus utama proyek adalah pada analisis hasil pelaksanaan, termasuk penyesuaian teknis yang diperlukan dan kesesuaian proses dengan timeline. Meskipun mengalami perubahan signifikan selama pelaksanaan, proyek berhasil diimplementasikan sesuai regulasi dengan perbedaan rute jalur awal dan akhir, melibatkan 9 ruas jalan, 42 tiang, dan panjang tarikan sepanjang 5.052 meter dalam waktu total 10 bulan.
Phytochemical screening, FTIR spectral analysis and hepatoprotective properties of Distimake dissectus (Jacq.) A.R. Simões & Staples
Authors: G. Prabhakar R. Nagaraju
Published: February 2024

Herbs used medicinally are a gift from nature to humans, helping to maintain, enhance, and protect our health in important ways. The current study investigates the phytochemical composition, FTIR spectral analysis, and hepatoprotective properties of Distimake dissectus (Jacq.) A.R. Simões & Staples. It is commonly called as ‘’alamo vine’’ belonging to family Convolvulaceae, is a perennial herb, weed and climber native to the United States and distributed across the globe. Traditionally, it is used to snakebite, urinary infection, sprains, cold and scabies chest problems, anti-asthmatic, anti- hyperglycemic, antinociceptive, anti-inflammatory, immunomodulatory, anticarcinogenic. Following a qualitative phytochemical extraction with hexane, chloroform, ethyl acetate and methanol, along with a hot continuous and successive extraction through a Soxhlet extractor. The phytochemical screening indicated the presence of alkaloids, flavonoids, saponins, phenolic compounds, tannins, and glycosides, among other compounds, additionally the quantification of phytochemical content demonstrated the total phenolic content, total flavonoid content, and proanthocyanins content. FT-IR spectroscopic analysis revealed various characteristic peak values with various functional groups hydroxyl group, alkane, nitrile, alkyne, ester, aromatic, alkene groups and etc., The hepatoprotective activity of the methanolic extract was evaluated using the MTT assay, showing concentration-dependent inhibition of cancer cells. The study sheds light on the therapeutic qualities of Distimake dissectus and provides beneficial insights for pharmacology and drug development research. The discovery of hepatoprotective plant-based compounds in these plants may pave the way for the creation of novel therapeutic hepatoprotective agents.
Molecular identification of fungal isolates from rhizospheric soil of medicinal plants
Authors: Aafreen Ushba , Haneef Mohammad
Published: February 2024

Further knowledge of the interactions between rhizospheric fungi and medicinal plants is needed to promote the manufacture of crude medications, as it has recently been clear how these fungi have a significant impact on the quality and quantity of crude pharmaceuticals through a specific fungus-host interaction. The present study was aimed to find out the diversities of fungi in the rhizospheric soil of medicinal plants particularly (Gingiber officinale, Calotropis gigantea, Endographis paniculata, Vigna mungo, Chrysopogon giganoids and Tinospora cordifolia) collected from CIMAP CSIR situated in Indian city Lucknow and from nearby Paikramau agriculture field Lucknow, U.P., India. The DNA of the rhizospheric fungal isolates was amplified through PCR for species level identification using a specific internal transcribed spacer primer (ITS1/ITS4). This study revealed that five different type of fungi identified surrounding the Rhizospheric region of the selected aforementioned plants such as Rhizopus oryzae, Fusarium incarnatum, Penicillium expansum, Aspergillus ochraceous and Aspergillus flavus further validated by sequencing the PCR findings and comparing them to other relevant sequences in GenBank (NCBI).
Isolation and identification of bacteria from solid waste deposit sites for the degradation of heavy metals
Authors: Gafoor Shaik Abdul , T. Raghavendra Pandu Brahmaji Rao
Published: February 2024

Heavy metals from solid waste deposits that are toxic, mutagenic, and carcinogenic contaminate natural water supplies and agricultural environments. The purpose of this project is to separate and characterize naturally occurring bacteria that can reduce and detoxify heavy metals (lead, cadmium, nickel, zinc, manganese, iron, copper, chromium, and mercury) from solid waste dumping sites. Ten strains in total were isolated from the samples; the two best-performing isolates, Shewanella oneidensis strain AGB 4 (Isolate 5) and Bacillus pumilus strain AGB 11 (Isolate 6) were recognized up to the genus level based on their 16S rRNA identification studies. These isolates demonstrated resistance to every heavy metal that was examined in the solid waste. The MICs for the two isolates varied in relation to the amounts of the heavy metals listed above. The solid waste isolates grew best at pH 7.0, 30°C and an incubation period of 24 hours. Utilizing an atomic absorption spectrophotometer to measure degradation potential, Shewanella oneidensis demonstrated the most removable capability for copper (60%) and the lowest removable capability for lead, arsenic and mercury (45%) and Bacillus pumilus demonstrated a reduction of 48% in mercury and arsenic and 65% in copper. Bacillus pumilus and Shewanella oneidensis may be able to break down heavy metals through plasmids, which could be used to change plasmids so they can carry the ability to accumulate heavy metals. Thus, determining the resistance to heavy metals and biodegradation potential of two bacteria could serve as a foundational investigation for the development of viable local biological remediation agents in solid waste deposit sites.
Assessment of wound healing potential in mice of formulations prepared from methanolic extract of Oxalis corniculata L. and Hypericum oblongifolium Choisy of Uttarakhand
Authors: Arati Tamta Arati Tamta
Published: February 2024

The skin develops a wound that is both anatomical and functional. Wound healing is a difficult process of tissue remodeling or repair following injury. In the past, various types of wounds have been treated and managed using plants and chemical components derived from plants. Various varieties are now being explored to establish an affordable, reliable and efficient delivery system for the treatment of wounds. This study used a mouse model to investigate the effects of Methanolic leaf extracts of Oxalis corniculata and Hypericum oblongifolium on wound healing. Oxalis corniculata L. and Hypericum oblongifolium Choisy plant leaf that had been dried by the air was ground up, extracted with methanol and made into formulation code gel F4, F6 and F8. The above formulations were then put topically to test their ability to speed up the healing of excision wound models. The wound contraction, epithelialization time and tensile strength were all measured. Increases in percentage wound contraction and tensile strength, as well as a reduction in the time needed for epithelialization, were seen with both F6 and F8 extract gel formulations. The results of this study correlated the Oxalis corniculata L. and Hypericum oblongifolium Choisy use of the plants by demonstrating that their leaf extracts had strong wound healing efficacy.
Nanomaterials and nanotechnology : A comprehensive study of synthesis, characterization and multifaceted applications
Authors: Mahendra Kumar Yadav Anwesha Sharma
Published: February 2024

This paper presents a comprehensive study of nanomaterials and nanotechnology, encompassing synthesis methodologies, advanced characterization techniques and diverse applications. Nanomaterials, engineered at the nanoscale, exhibit unique properties and hold immense promise for revolutionizing various industries. The study covers five key subheadings, addressing synthesis approaches, characterization methods, multifaceted applications in medicine, energy, electronics and future prospects in the field. The core of this comprehensive study delves into the multifaceted applications of nanomaterials, covering a broad spectrum of fields ranging from medicine and pharmaceuticals to environmental science and renewable energy. In the medical realm, the paper discusses the revolutionary impact of nanomaterials in drug delivery systems, targeted cancer therapies, and diagnostic tools. The unique properties of nanomaterials, such as increased surface area and reactivity, are shown to enhance the efficacy of drugs and treatment methods. The interdisciplinary nature of nanomaterials and their vast potential make this field a cornerstone of future advancements in science and engineering.
Awareness and developments in the treatment of pompe disease : A review
Authors: Prasad P. Dharani
Published: February 2024

Pompe disease is a hereditary, uncommon (one in every 40,000 births) and frequently deadly ailment that affects the heart and skeletal muscles. Mutations in a gene that produces an enzyme called acid alpha-glucosidase cause it (GAA). This article is meant to raise awareness among Pompe disease patients. We also talk about new future treatments on the market for the treatment of pompe illness. Pompe disease is an inherited disorder caused by the build-up of a complex sugar called glycogen in the body’s cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally. Researchers have described three types of pompe disease, which differ in severity and the age at which they appear. These types are known as classic infantile-onset, non-classic infantile-onset and late-onset. The classic form of infantileonset pompe disease begins within a few months of birth. Infants with this disorder typically experience muscle weakness (myopathy), poor muscle tone (hypotonia), an enlarged liver (hepatomegaly) and heart defects. Affected infants may also fail to gain weight and grow at the expected rate (failure to thrive) and have breathing problems. If untreated, this form of pompe disease leads to death from heart failure in the first year of life. The non-classic form of infantile-onset pompe disease usually appears by age 1. It is characterized by delayed motor skills (such as rolling over and sitting) and progressive muscle weakness. The heart may be abnormally large (cardiomegaly), but affected individuals usually do not experience heart failure. The muscle weakness in this disorder leads to serious breathing problems and most children with non-classic infantile-onset pompe disease live only into early childhood.
MONITORING PEMBACAAN TIMER DAN SUHU MOTOR PADA CENTRIFUGE BERBASIS ARDUINO AT MEGA16
Authors: Abdillah Khairil , Situmorang Harold , Siregar Roni Rahmad
Published: February 2024

Centrifuge is a tool used to separate the liquid according to specific gravity, this tool is used in the laboratory to separate samples such as blood, urine, and others. The main component of Centrifuge is an DC motor that serves to rotate the sample with centrifugal force with the density and time specified. Centrifuge that the author made using microcontroller At Mega 328p and consists of DC motor components, motor drivers, 20x4 lcd, speed sensor, buzzer and keypad. Sensors used are optocoupler sensors that function to determine the speed of the motor, motor drivers are used to adjust the speed of the motor according to the wishes of the user, LCD function to display the speed of the motor and timer, buzzer will sound when the process of separation of the sample has been completed, keypad as input speed, timer and also check the temperature on the motor. Centrifuge is using blood samples, On the motor there are sensors used to determine the speed of the motor. When the speed has been reached, the motor driver will work to control the motor to stay in accordance with the desired speed.
RANCANG BANGUN ALAT PENCATAT AKTIFITAS JANTUNG MENGGUNAKAN ARDUINO UNO BERBASIS ANDROID
Authors: Abdillah Khairil , Priyulida Fitria , Mendrofa Abed Nego
Published: February 2024

The electrical activity of the heart is the basis elektrokardiograph (ECG) in observing the condition of the heart , a series of ECG consists of amplifier biopotensial of an instrument ECG became the main component in this study , records heart activity is still a burden to the medical world in the use and the results of the expected output .In this study biolistrik signal received from the ECG to be controlled via arduino , and data received through arduino will be sent via Bluetooth and android will be shown on the display , Bluetooth serves as the sender and the data receiver ( RX,TX). Results released by android is a graphic display that can be stored in the form of images in JPEG format on a regular basis or in real time so as to facilitate and reduce the use of paper in printing graphics imaginable on ECG in general that still use paper as the output.
ANALISA PEMELIHARAAN KOREKTIF TERHADAP INFUS PUMP MINDRAY BENEFUSION VP5
Authors: Abdillah Khairil , Dabukke Hotromasari , Maulana Fazri , Br Tarigan Greace Seselia
Published: February 2024

Research has been done on the infusion pump. As for the purpose of this study is to determine the problem of repairing the infusion pump. Corrective maintenance is maintenance action taken to overcome damage or congestion that occurs repeatedl, then take corrective action on teh tool. An infusion pump is a medical device that is used to provide additional electrolytes in the form of a liquid that is injected into the patient’s body in a certain amount through a vein. The display of the infusion pump device does not turn on due ti the disconnection of the flexible cable connector between the LCD and the device’s mother board. During operation a red high sound alarm appears for 10 seconds. When checking the infus pump., it was found that the infusion hose was loose for the patient user, in other checks, the infusion pump clamp was found to be broken. The research is that the infusion pump has been functioning properly after checking and repairing. Maintenance of the infusion pump must be routine and scheduled to prevent damage so that the life of the tool is long. Testing and calibration of the infusion pump, especially on the parameters of the infusion pump, it is mandatory to carry out routine checks on the infusion pump.
ANALISIS KONTROL LAMPU OPERASI MENGGUNAKAN SENSOR JARAK BERBASIS MIKROKONTROLER ARDUINO UNO
Authors: Abdillah Khairil , Riduan Muhammad
Published: February 2024

The operating lamp is one of the madical devices that has a very important role in the world of health, especially at The nimal:pain during surger. The purpose of this study was to determine the analysis of operating lamp control using a proximity sensor based on the Arduino Uno microcontroller, to determine the effect of distance to objects on operaring lamp devices. Adjust the distance between the object to the operating lampu so that the module will automatically assign a distance value according to the object to the operating lamp. The results obtained in this study are at a distance of 50 cm the light value to the object is 8023, at a distance of 100 cm the light value is obtained ot the object 2,827 at a distance of 140 cm, the value of light ot the object 1,298. the conclusion of this study is that the closer the distance to the operating lamp is to the object, the higher the intensity and vice versa because the series of readings of light and distance values automatically reads the distance and ligh values. Yes operating lights against objects.
SISTEM MONITORING SPEED SETTING PADA ROLLER MIXER BERBASIS MIKROKONTROLER ARDUINO UNO
Authors: Sijabat Salomo , Andany Arif
Published: February 2024

Roller mixer is a laboratory tool that serves to mix blood samples and reagents.  In this case, the substances that are mixed are blood and anti-clotting agents (coagulants).  In the process of mixing the blood, the timer and the rotational value of the motor are set by the selector switch.  The design of the speed setting of the roller mixer tool is made so that the user can control and monitor how much the value of the motor speed used is displayed on the 16x2 LCD display. This research will be conducted at the Electronics Laboratory of Sari Mutiara University, Helvetia District, Medan City.  This type of research method is experimental research, namely conducting direct experiments.  The components in monitoring this tool are microcontroller, display, timer setting, speed setting and roller. After carrying out the research process on the design of this tool, the measurement results obtained from the Infrared Sensor are displayed on the LCD, with a minimum speed measurement of 36, Medium 38 and a maximum of 44 rpm.  With a comparison from a thacometer with an average value of Minimum 44 Medium 54 and maximum 56.
ANALISIS TIMER DAN SENSOR SUHU TUBUH BAYI PADA PERALATAN PHOTOTHERAPY BERBASIS ARDUINO UNO
Authors: Aruan Dyna Grace Romatua , Siallagan Wilson , Avisienna
Published: February 2024

Jaundice (Neonatal Jaundice) or better known as Jaundice in newborns is a normal thing and usually occurs 1-2 weeks after the birth of the baby. Based on statistics, 60% of the number of newborns look yellow less than 24 hours after the birth of the baby which indicates that the level of bilirubin in the blood is high. This condition is called hyperbiliruinemia. Hyperbilirubinemia is the term used for neonatal jaundice after laboratory results show an increase in bilirubin levels. Bilirubin is the result of the breakdown of hemoglobin due to damaged red blood cells and requires immediate medical attention. If left untreated, excess bilirubin in the blood can enter the brain and damage the brain. Yellow color in babies is usually seen on the forehead and the whites of the eyes, then down to the body, arms and legs. One of the most common medical treatments to cure jaundice is using Phototherapy. Basically babies who suffer from jaundice will be irradiated with blue light which has a long range of 400-510 nm for a certain period of time until their Bilirubin level drops to a level that is safe for the baby.
SISTEM KONTROL LAMPU OPERASI TERHADAP BRIGHTNESS (LOW, MEDIUM, HIGH) BERBASIS ARDUINO UNO
Authors: Manurung Kesaktian , Yanti Nelly , Alrasyad Muhammad Iqbal
Published: February 2024

The operating lamp is one of the medical devices that has a very important role in the world of health, especially in hospitals when performing surgery. The purpose of this study was to determine the design of operating lamps for Arduino Uno-based Brightnees. To find out the low, medium, high light settings when in operation. Type of Research This research uses an experimental research type. By measuring, testing and collecting data directly at a distance of 70 meters & 100 meters using a Bh1750 sensor and compared with Lux Meter measurements on the design of operating lamps on Arduino Uno-based brightnees. The results obtained From the measurements that have been carried out using the Bh1750 sensor 5 times at a distance of 70 & 100 meters, the authors get an average, low distance of 70 M: 201.2, low distance of 100M: 43.4. Medium distance 70M: 824.2 medium distance 100M: 242.4. And high distance 70 M: 1,311.8 high distance 100 M: 700. The conclusion obtained from this study is that the farther the distance of light from the object, the less amount of light appears, and conversely, the closer the intensity of light to the object, the greater the amount of light. emerging.
ANALISIS PEMELIHARAAN SUCTION PUMP DI RSUP HAJI ADAM MALIK MEDAN
Authors: Primasyukra Mhd. Aldi , Sinulaki Yogi Alfares
Published: February 2024

Checking the accuracy of the required medical equipment on the suction pump calibrator with measurements that have been made using a standardized pressure gauge. The purpose of this study was to determine the maintenance of the suction pump at Haji Adam Malik Hospital Medan in 2022. The method used in this study was descriptive qualitative. The tool used is a suction pump and a questionnaire as a measuring tool used. The results showed that the motor rotation function, cable resistance, and hose were not in accordance with the suction pump maintenance standard, and encountered problems, namely the tool could not work as usual, so that maintenance repairs were carried out on the tool, namely readjusting the value according to the standard on the suction pump tool, so that the tool was able to work well.
ANALISIS SISTEM KERJA DAN PENGARUH NON INVASIVE BLOOD PRESSURE PADA PATIENT MONITOR
Authors: Ulina Sri , Nazara Defi Purnama
Published: February 2024

Patient Monitor is a device that monitors physiological conditions in the form of NIBP (Non-Ivasive Blood Pressure) blood pressure, temperature, respiration, SPO2 and the shape of the heart pulse continuously. The purpose of this study was to find out how the system works and the use of Non Iinvasive Blood Pressure is good in order to get maximum results. This research is a descriptive and qualitative method, namely by analyzing the Work System and the Effect of Noun Invasive Blood Pressure measurement on the Patient Monitor. The results obtained are the NIBP working system on the patient monitor device consisting of power supply, motor, air valve, microprocessor, display. The blood pressure measurement system uses a cuff with air pressure generated by a motor. The conclusion of this study is that the NIBP works using a pneumatic system, namely using air pressure, where the cuff is inflated until the pressure reaches a maximum above systolic pressure, where the arteries are effectively blocked. Then the cuff pressure is reduced to a constant level, the pressure traducer provides an analog signal to the digital hardware during the process of obtaining the systolic, diastolic and mean pressures.
RANCANG BANGUN KECEPATAN PUTARAN PADA CENTRIFUGE BERBASIS ARDUINO AT MEGA 328P
Authors: Aruan Dyna Grace Romatua , Sijabat Salomo , Munthe Amran Jonathan
Published: February 2024

Centrifuge is a tool used to separate the liquid according to specific gravity, this tool is used in the laboratory to separate samples such as blood, urine, and others. The main component of Centrifuge is an DC motor that serves to rotate the sample with centrifugal force with the density and time specified. Centrifuge that the author made using microcontroller At Mega 328p and consists of DC motor components, motor drivers, 20x4 lcd, speed sensor, buzzer and keypad. Sensors used are optocoupler sensors that function to determine the speed of the motor, motor drivers are used to adjust the speed of the motor according to the wishes of the user, LCD function to display the speed of the motor and timer, buzzer will sound when the process of separation of the sample has been completed, keypad as input speed and timer. On the motor there are sensors used to determine the speed of the motor. When the speed has been reached, the motor driver will work to control the motor to stay in accordance with the desired speed.
ANALISIS KECEPATAN PUTARAN HOTPLATE MAGNETIC STIRRER BERBASIS ARDUINO UNO
Authors: Dabukke Hotromasari , Primasyukra Mhd. Aldi , Lasiyah Nani , Gaol Midun Andrike Lumban
Published: February 2024

The Arduino Uno Based Hotplate Magnetic Stirrer Rotational Speed ​​Design has been successfully carried out. The function is to stir and heat one solution with another solution which aims to make a homogeneous solution with the help of a Magnetic stir bar (Stir Bar). The purpose of this design is to know the design of the HotPlate Magnetic Stirrer with 400 Rpm Rotation Speed ​​Settings and to determine the accuracy of the Hotplate Magnetic Stirr rotation speed. The method used is the experimental method. The components in this design are Arduino uno and consist of DC Stepper motor components, motor drivers, 20x4 lcd. The working principle of the design of the hotplate magnetic stirrer based on Arduino Uno. The PLN AC 220V current enters the power supply which converts to a DC voltage of 12V 10A, then Arduino Uno receives a DC voltage of 12V to turn on circuits such as motor drivers that require 12V voltage directly from the power supply, 9V stepper motors, 5V buzzers. Furthermore, the stepper motor will run according to the command set on keyped. To compare the rotational speed settings, use the tachometer calibration tool. The test results show the Rotational Speed ​​of the Arduino Uno-Based Hotpate Magnetic Stirrer, the rpm rotation speed is in accordance with the settings and the results obtained are 10% tolerance. The results of measuring the voltage on the power supply.
ANALISA PENYELESAIAN MASALAH DAN PERBAIKAN ALAT PATIENT MONITOR DI RSUP H. ADAM MALIK MEDAN
Authors: Priyulida Fitria , Manurung Kesaktian , Maulana Fazri , Malau Riris
Published: February 2024

Research on patient monitor tools has been carried out. The purpose of this study was to determine the problem of repairing the patient monitor tool. Corrective maintenance is maintenance action taken to overcome damage or congestion that occurs repeatedly, then take corrective action on the tool. Patient monitor is a tool that is used to monitor the patient's physiological condition. The purpose of this study is Troubleshooting (damage) patient monitor tools. Improvements to the patient monitor tool with the results of the study found that troubleshooting was seen through the results of less accurate blood pressure calculations so that it affected the diagnosis process in NIBP (Non Invasive Blood Pressure), Spo2 (Oxygen Pressure Saturation) patients. Incorrect reading of SpO2 results can be affected by sensor damage which when diagnosing patients, Ecg (Electrocardiograph) affects the results of diagnostics made by the instrument on patients, Misdiagnosis can occur due to incorrect placement of electrodes/tappers, damaged electrodes, Temperature (temperature) on the temperature sensor, namely damage to the temperature connector cable and the occurrence of undetected temperature results on the patient monitor tool. The research is that the patient monitor has been functioning properly after checking and repairing. Maintenance of the patient monitor must be routine and scheduled to prevent damage so that the age of use of tools and accessories is longer. Testing and calibration of patient monitor tools, especially on patient monitor parameters, must carry out routine checks on patient monitors, especially patient monitor accessories.