bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical impact of rehabilitation and ICU diary on critically ill patients: A systematic review and meta‐analysis
Authors: Ishinuki Tomohiro , Zhang Ling , Harada Keisuke , Tatsumi Hiroomi , Kokubu Nobuaki , Kuno Yoshika , Kumasaka Kanon , Koike Rina , Ohyanagi Toshio , Ohnishi Hirofumi , Narimatsu Eichi , Masuda Yoshiki , Mizuguchi Toru
Published: January 2023

Background

Various physical and mental sequelae reduce the quality of life (QOL) of intensive care unit (ICU) patients. Current guidelines recommend multi‐angular approaches to prevent these sequelae. Some studies have demonstrated the clinical effectiveness of rehabilitation or the ICU diary against these sequelae, whereas others have not.

Aim

The aims of the present study were to establish whether rehabilitation or the ICU diary was useful for reducing the severity of anxiety, depression, and post‐traumatic stress disorder (PTSD) in ICU patients. We also investigated whether these interventions improved the QOL of these patients.

Study design

We conducted a systematic review and meta‐analysis of relevant randomized controlled trials published between January 1, 1985, and October 19, 2022, with the following search engines: PubMed, CHINAHL, all Ovid journals, and CENTRAL. The hospital anxiety and depression scale (HADS), the short‐form health survey (SF‐36), the EuroQol 5‐dimensions, 5‐levels (EQ‐5D‐5L), and the Impact of Event Scale‐Revised (IES‐R) were used as outcome measures. The quality of evidence across all studies was independently assessed using Review Manager software (v.5.4).

Results

We included 12 rehabilitation studies and five ICU diary studies. Rehabilitation had no significant effects on HADS‐anxiety, HADS‐depression, or EQ‐5D‐5L, but significantly improved the physical component summary (PCS) [MD = 3.31, 95%CI (1.33 to 5.28), p = .001] and mental component summary (MCS) [MD = 4.31, 95%CI: (1.48 to 7.14), p = .003] of the SF‐36. The ICU diary significantly ameliorated HADS‐anxiety [MD = 0.96, 95%CI: (0.21 to 1.71), p = .01], but did not affect HADS‐depression, the IES‐R, or the PCS or MCS of the SF‐36.

Conclusions

The present study showed that rehabilitation initiated after discharge from the ICU effectively improved SF‐36 scores. The ICU diary ameliorated HADS‐anxiety. Neither rehabilitation nor the ICU diary attenuated HADS‐depression or IES‐R in this setting. Rehabilitation and the ICU diary partially improved the long‐term prognosis of ICU patients.

Relevance to clinical practice

The present study provides evidence for the beneficial effects of rehabilitation and the ICU diary for ICU patients. Rehabilitation alone does not ameliorate anxiety, depression, or PTSD symptoms, but may improve QOL. The ICU diary only appeared to ameliorate anxiety.
Evolving Fertility Goals and Behaviors in Current U.S. Childbearing Cohorts
Authors: Guzzo Karen Benjamin , Hayford Sarah R.
Published: January 2023

In the post‐Recession era, U.S. fertility rates have continued to fall. It is unclear if these declines are driven by shifts in fertility goals or growing difficulty in achieving goals. In this paper, we construct synthetic cohorts of men and women to examine both cross‐cohort and within‐cohort changes in fertility goals using multiple cycles of the National Survey of Family Growth. Although more recent cohorts exhibit lower achieved fertility at younger ages than earlier cohorts at the same age, intended parity remains around two children, and intentions to remain childless rarely exceed 15 percent. There is weak evidence of a growing fertility gap in the early 30s, suggesting more recent cohorts will need considerable childbearing in the 30s and early 40s to “catch up” to earlier goals, yet low‐parity women in their early 40s are decreasingly likely to have unfulfilled fertility desires or intentions to have children. Low‐parity men in their early 40s, though, are increasingly likely to intend children. Declines in U.S. fertility thus seem to be largely driven not by changes in early‐life fertility goals so much as either a decreasing likelihood of achieving earlier goals or, perhaps, shifts in the preferred timing of fertility that depress period measures.
Policy reform and farmers' coping strategies: The case of corn price shocks in Heilongjiang Province of China
Authors: Zheng Zhihao , Gao Yang , Nayga Rodolfo M. , Zhao Yinyu
Published: January 2023

A substantial decrease in corn prices caused by the policy reform in 2016 in China led to heterogeneous supply responses of corn producers: decreasing corn acreage, making no change in corn acreage, and expanding corn acreage. We investigate the causes and consequences of cropland allocation of the supply responses using the balanced panel data on corn‐producing households from 2015 through 2016 in Heilongjiang Province. We find that the corn producers largely acted in accordance with their own household resource endowments to make their choice decisions in response to the corn price shocks. Our results show that the decrease in corn prices led to a small decline in total corn acreage and a considerable increase in total acreage for soybeans and rice in 2016 and that the increase in total soybean acreage was more through area expansion rather than through substitution. Our results also show that crop structure for large‐scale producers was more responsive to corn price than for medium‐ and small‐scale producers. Given that continuous corn rotation prevails currently in Heilongjiang, our major finding suggests that the acreages planted to corn and soybeans cannot be easily adjusted by the market.
Modes of action of lysophospholipids as endogenous activators of the TRPV4 ion channel
Authors: Benítez‐Angeles Miguel , Romero Ana E. López , Llorente Itzel , Hernández‐Araiza Ileana , Vergara‐Jaque Ariela , Real Fernando H. , Gutiérrez Castañeda Óscar Eduardo , Arciniega Marcelino , Morales‐Buenrostro Luis E. , Torres‐Quiroz Francisco , García‐Villegas Refugio , Tovar‐y‐Romo Luis B. , Liedtke Wolfgang B. , Islas León D. , Rosenbaum Tamara
Published: January 2023

The Transient Receptor Potential Vanilloid 4 (TRPV4) channel has been shown to function in many physiological and pathophysiological processes. Despite abundant information on its importance in physiology, very few endogenous agonists for this channel have been described, and very few underlying mechanisms for its activation have been clarified. TRPV4 is expressed by several types of cells, such as vascular endothelial, and skin and lung epithelial cells, where it plays pivotal roles in their function. In the present study, we show that TRPV4 is activated by lysophosphatidic acid (LPA) in both endogenous and heterologous expression systems, pinpointing this molecule as one of the few known endogenous agonists for TRPV4. Importantly, LPA is a bioactive glycerophospholipid, relevant in several physiological conditions, including inflammation and vascular function, where TRPV4 has also been found to be essential. Here we also provide mechanistic details of the activation of TRPV4 by LPA and another glycerophospholipid, lysophosphatidylcholine (LPC), and show that LPA directly interacts with both the N‐ and C‐terminal regions of TRPV4 to activate this channel. Moreover, we show that LPC activates TRPV4 by producing an open state with a different single‐channel conductance to that observed with LPA. Our data suggest that the activation of TRPV4 can be finely tuned in response to different endogenous lipids, highlighting this phenomenon as a regulator of cell and organismal physiology.

image

Key points

The Transient Receptor Potential Vaniloid (TRPV) 4 ion channel is a widely distributed protein with important roles in normal and disease physiology for which few endogenous ligands are known.

TRPV4 is activated by a bioactive lipid, lysophosphatidic acid (LPA) 18:1, in a dose‐dependent manner, in both a primary and a heterologous expression system.

Activation of TRPV4 by LPA18:1 requires residues in the N‐ and C‐termini of the ion channel.

Single‐channel recordings show that TRPV4 is activated with a decreased current amplitude (conductance) in the presence of lysophosphatidylcholine (LPC) 18:1, while LPA18:1 and GSK101 activate the channel with a larger single‐channel amplitude.

Distinct single‐channel amplitudes produced by LPA18:1 and LPC18:1 could differentially modulate the responses of the cells expressing TRPV4 under different physiological conditions.
Sand Consolidation Using Enforced Calcium and Magnesium Fluoride Precipitation
Authors: Hassan Amjed , Mahmoud Mohammed , Abu-Khamsin Sidqi , El-Husseiny Ammar , Al-Karnos Assem
Published: January 2023

Sand production is a common problem that interrupts hydrocarbon production from unconsolidated formations. Different chemical and mechanical methods are used to prevent solid production either by consolidating the sand particles or installing downhole screens. This study presents a novel approach for sand consolidation using enforced calcium and magnesium precipitation. The used chemicals are ammonium hydrogen fluoride, calcium oxide, and magnesium oxide solutions. In this work, different measurements were carried out to assess the performance of the new consolidation method. Also, the impact of soaking the consolidated sand in freshwater, toluene, and HCl was examined. The rock mineralogy was determined before and after each soaking treatment using X-ray diffraction (XRD) analysis. The nuclear magnetic resonance (NMR) technique was used to evaluate the pore system at different stages. In addition, scanning electron microscope (SEM) technique was used to examine the morphology and chemistry changes after each chemical treatment. Finally, the rock strength was measured before and after the treatment using a scratch test. Results indicate that the proposed chemical method can significantly improve the sand consolidation and increase the rock strength to 34 MPa (4931 psi). Soaking the consolidated sand sample in water and toluene showed minor alterations in the rock properties. However, using HCl lead to increasing rock permeability due to mineral dissolution. The strength measurements showed that the consolidated sand can withstand the water and toluene treatment, and the rock strength was reduced by less than 10%. Overall, a new chemical treatment is presented to improve the sand consolidated utilizing enforced calcium and magnesium precipitation. The consolidated sand sample showed very reasonable rock strength which can prevent sand migration.
Systematic study of InP/InGaAsP heated plasma etching and roughness improvement for integrated optical devices
Authors: Vyas Kaustubh , Awan Kashif M. , Dolgaleva Ksenia
Published: January 2023

Indium Phosphide (InP) is one of the most widely commercialized III–V semiconductor materials for making efficient lasers operating in the O-band and C-band. It is also gaining significant attention as a material platform for passive integrated optical devices operating in the telecommunication wavelength range for optical communication networks and sensing. Fabrication of such devices requires a process of lithography for pattern writing followed by plasma etching for transferring the pattern into the semiconductor material. InP is one of the most difficult materials to etch due to the fact that the etching by-products (InClx) are not volatile at temperatures less than 150 °C. There have been some studies showing InP etching at lower temperatures and room temperatures. However, after carefully studying these processes using multiple plasma etching tools, we found that the claimed processes are not repeatable because of the low volatility of the by-products at room temperature. In this work, we demonstrate a systematic study of etching InP using methane-hydrogen-based chemistry at low temperatures (60 °C) and chlorine-based chemistry at high temperatures (190 °C).
Bulk and surface chemical compositions and microstructure properties of CaF2:Y3+ material
Authors: Yagoub Mubarak Y. A. , Swart Hendrik C. , Coetsee Elizabeth
Published: January 2023

The structural and chemical compositions of Y3+ ion-doped CaF2 were investigated as a possible lanthanide hosting material. A series of CaF2 nanomaterials doped with various concentrations of Y3+ ions under the chelating agent ethylene diamine tetraacetic acid (EDTA) were synthesized using the hydrothermal method. The x-ray diffraction results demonstrated that a mixture of cubic CaF2 and [CaY]F2 phases gradually formed with an increasing Y3+ ion concentration. A single [CaY]F2 cubic phase was formed when EDTA was added as the chelating agent. Scanning electron microscopy results demonstrated that the particle size and the morphology of the material depended on the Y3+ concentration and that EDTA (0.5 g) produced a spherical morphology. The surface and bulk chemical compositions were determined using a combined system of soft x-ray photoemission spectroscopy (XPS) (Al-Kα 1486.7 eV) and hard x-ray photoemission spectroscopy (HAXPES) (Cr-Kα 5414.7 eV). The relative changes in the chemical composition of the surface and subsurface/bulk were investigated. The combined XPS-HAXPES analysis demonstrated that the surface impurities in the accessible peaks (Ca 2p, Y 3d, and F 1s) completely diminished in the subsurface region. However, XPS-HAXPES analysis confirmed that the composition of the [CaY]F2 nanomaterial on the surface differs from that in the subsurface region.
The Big Story of a “Small” Football Club: Gümüşlükspor as an Alternative Model Experience for Turkey
Authors: İnal Rahşan
Published: January 2023

This article argues that counter-hegemony, which is at the heart of sports activism, is not just an action but also the construction of alternative institutional structures. For this purpose, it investigates the practices of an amateur football club and discusses the structural problems of the Turkish amateur football league. The data, collected during a 6-month field study, were interpreted from a critical perspective, using a dialectical dialogue method to apply the theory of hegemony in sports by applying Antonio Gramsci’s concept of the “organic intellectual.” Consequently, this sports club has provided socialization and free football training for children while creating an alternative football culture with local characteristics that are opposed to class and gender inequalities and to homophobic attitudes common in sport.
SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators
Authors: Honrubia Jose M. , Gutierrez-Álvarez Javier , Sanz-Bravo Alejandro , González-Miranda Ezequiel , Muñoz-Santos Diego , Castaño-Rodriguez Carlos , Wang Li , Villarejo-Torres Marta , Ripoll-Gómez Jorge , Esteban Ana , Fernandez-Delgado Raul , Sánchez-Cordón Pedro José , Oliveros Juan Carlos , Perlman Stanley , McCray Paul B. , Sola Isabel , Enjuanes Luis
Published: January 2023

Three highly pathogenic human CoVs have been identified: SARS-CoV, MERS-CoV, and SARS-CoV-2. The E protein PBMs of these three CoVs were virulence factors.
A Microtubule-Associated Protein Is Essential for Malaria Parasite Transmission
Authors: Wichers-Misterek Jan Stephan , Binder Annika M. , Mesén-Ramírez Paolo , Dorner Lilian Patrick , Safavi Soraya , Fuchs Gwendolin , Lenz Tobias L. , Bachmann Anna , Wilson Danny , Frischknecht Friedrich , Gilberger Tim-Wolf
Published: January 2023

A key structural feature driving the transition between different life cycle stages of the malaria parasite is the unique three-membrane pellicle, consisting of the parasite plasma membrane (PPM) and a double membrane structure underlying the PPM termed the inner membrane complex (IMC). Additionally, there are numerous linearly arranged intramembranous particles (IMPs) linked to the IMC, which likely link the IMC to the subpellicular microtubule cytoskeleton.
Characterization of Gut Microbiota Compositions along the Intestinal Tract inCD163/pAPNDouble Knockout Piglets and Their Potential Roles in Iron Absorption
Authors: Zhang Xiu-Ling , Zhou Yan-Rong , Xu Song-Song , Xu Si , Xiong Yu-Jian , Xu Kui , Xu Chang-Jiang , Che Jing-Jing , Huang Lei , Liu Zhi-Guo , Wang Bing-Yuan , Mu Yu-Lian , Xiao Shao-Bo , Li Kui
Published: January 2023

Iron deficiency is a major risk factor for iron deficiency anemia, which is among the most common nutritional disorders in piglets. However, it remains unclear how the gut microbiota interacts with host iron absorption.
Contemporary Evaluation of Tebipenem
In Vitro
Activity against Enterobacterales Clinical Isolates Causing Urinary Tract Infections in US Medical Centers (2019–2020)
Authors: Mendes Rodrigo E. , Arends S. J. Ryan , Streit Jennifer M. , Critchley Ian , Cotroneo Nicole , Castanheira Mariana
Published: January 2023

The occurrence of urinary-tract Enterobacterales pathogens producing ESBL enzymes in community and nosocomial settings continues to increase, as does the coresistance to fluoroquinolones, trimethoprim-sulfamethoxazole and nitrofurantoin often exhibited by these pathogens. This scenario complicates the clinical empirical and guided management of UTI by precluding the use of oral and many intravenous options.
Antifungal Activity of Volatile Components from Ceratocystis fimbriata and Its Potential Biocontrol Mechanism on Alternaria alternata in Postharvest Cherry Tomato Fruit
Authors: Xing Shijun , Gao Yating , Li Xue , Ren Huan , Gao Yang , Yang Hui , Liu Yanmei , He Shuqi , Huang Qiong
Published: January 2023

In this research, the volatile organic compounds (VOCs) produced based on
C. fimbriata
exhibited strong antifungal activity against the fungal pathogen
A. alternata
. Our aim is to explore their bacteriostatic components.
Injuries among children attributed to violence and social funding: a 10-year observational study
Authors: Morris Louise , Naumann David N , Reilly John-Joe , Kitchen Samuel , Blackburn Lauren , Bishop Jonathan , Brooks Adam
Published: January 2023

Background

Mechanisms and patterns of injury in children are changing, with violent mechanisms becoming more prevalent over time. Government funding of services for children and young people has reduced nationally over the last decade. We aimed to investigate the trends in admissions of injured children to a Major Trauma Centre (MTC) and examine the relationship between injuries sustained by violent mechanisms and local authority funding of children and youth services within the same catchment area.

Methods

A 10-year observational study included all patients aged<18 years treated at a regional MTC between April 2012 and April 2022. Number of admissions with violent trauma, mechanism of injury, requirement for operative intervention and mortality were compared with published annual local authority expenditure reports.

Results

1126 children were included; 71.3% were boys, with median age 11 years (IQR 3–16). There were 154/1126 (14%) children who were victims of violent trauma; they were more likely to be boys than children injured by non-violent mechanisms (84% vs 69%). The proportion of injuries attributed to violence increased over the study period at the same time as reductions in local authority funding of services for the early years, families and youth services. However, there were insufficient data to formally assess the interdependency between these factors.

Conclusions

The proportion of injuries attributed to violence has increased over time, and government spending on specific children and young people’s services has decreased over the same time period. Further work is needed to examine the interdependency between spending and violent injuries in children, and public health interventions to target violence-related injuries should take into account youth service funding.
Impact of policy alterations on elective percutaneous coronary interventions in Japan
Authors: Morishita Tetsuji , Takada Daisuke , Shin Jung-ho , Kunisawa Susumu , Fushimi Kiyohide , Imanaka Yuichi
Published: January 2023

Objective

Establishing appropriate percutaneous coronary intervention (PCI) in stable angina pectoris (SAP) has become a distinctive performance measure worldwide. Clinical guidelines call for documenting ischaemia in patients with SAP prior to elective PCI. The Japanese Ministry of Health, Labour and Welfare introduced a new reimbursement policy in April 2018 to promote the appropriate and judicious implementation of PCI. The 2018 reimbursement changes clarified the required proof of ischaemia. Tests to evaluate functional ischaemia and coronary stenosis have been added as a requirement for reimbursement. We examined whether this reimbursement revision had an impact on PCI procedures for SAP in Japan.

Methods

We used administrative claims data in Japan’s Diagnosis Procedure Combination database from April 2014 through March 2020. We used interrupted time series analyses with a control to ascertain the impacts on elective PCI procedures before and after the Japanese reimbursement revision. The primary outcome was the change in elective PCI procedures per month. Emergent PCI procedures served as a control group.

Results

A total of 773 240 PCI procedures were identified between April 2014 and March 2020: 388 817 and 180 462 elective PCIs before and after the reimbursement revision, respectively. After the 2018 reimbursement revision, significant trend changes were found in elective PCI procedures per month (−106.3, 95% CI −155.8 to −56.8, p<0.01), while the number of emergent PCIs remained stable throughout the study period.

Conclusions

After revising the reimbursement tariff for elective PCIs in 2018, there was a significant reduction in elective PCI procedures per month.
Decoherence and Landauer’s principle in qubit-cavity quantum-field-theory interaction
Authors: Xu Hao , Chen Si Yu , Ong Yen Chin
Published: January 2023

We consider quantum decoherence and Landauer’s principle in qubit-cavity quantum field theory (QFT) interaction, treating the qubit as the system and cavity QFT as the environment. In particular, we investigate the changes that occur in the system with a pure initial state and environment during the decoherence process, with or without energy dissipation, and compare the results with the case in which the initial state of the system is a mixed state and thus decoherence is absent. When we choose an interaction Hamiltonian such that the energy and coherence of the system change simultaneously, the population change of the system and the energy change are the same when the initial state is mixed. However, the decoherence terms increase the von Neumann entropy of the system. In this case the energy change and decoherence of the system are not independent physical processes. The decoherence process maintains unitarity. On the other hand, if the interaction Hamiltonian does not change the energy of the system, there is only the decoherence effect. The environment will be a distribution in the basis of the displaced number state and always increases the energy. Landauer’s principle is satisfied in both cases.
Performance Evaluation of Error-Correcting Output Coding Based on Noisy and Noiseless Binary Classifiers
Authors: Kumoi Gendo , Yagi Hideki , Kobayashi Manabu , Goto Masayuki , Hirasawa Shigeichi
Published: January 2023

Error-correcting output coding (ECOC) is a method for constructing a multi-valued classifier using a combination of given binary classifiers. ECOC can estimate the correct category by other binary classifiers even if the output of some binary classifiers is incorrect based on the framework of the coding theory. The code word table representing the combination of these binary classifiers is important in ECOC. ECOC is known to perform well experimentally on real data. However, the complexity of the classification problem makes it difficult to analyze the classification performance in detail. For this reason, theoretical analysis of ECOC has not been conducted. In this study, if a binary classifier outputs the estimated posterior probability with errors, then this binary classifier is said to be noisy. In contrast, if a binary classifier outputs the true posterior probability, then this binary classifier is said to be noiseless. For a theoretical analysis of ECOC, we discuss the optimality for the code word table with noiseless binary classifiers and the error rate for one with noisy binary classifiers. This evaluation result shows that the Hamming distance of the code word table is an important indicator.
The Effects of Natural Sounds and Proxemic Distances on the Perception of a Noisy Domestic Flying Robot
Authors: Wang Ziming , Hu Ziyi , Rohles Björn , Ljungblad Sara , Koenig Vincent , Fjeld Morten
Published: January 2023

When flying robots are used in close-range interaction with humans, the noise they generate, also called consequential sound, is a critical parameter for user acceptance. We conjecture that there is a benefit in adding natural sounds to noisy domestic drones. To test our hypothesis experimentally, we carried out a mixed-methods research study (N = 56) on reported user perception of a sonified domestic flying robot with three sound conditions at three distances. The natural sounds studied were, respectively, added to the robot’s inherent noises during flying; namely, a
bird
song and a
rain
sound, plus a control condition of no added sound. The distances studied were set according to proxemics; namely,
near
,
middle
, and
far
. Our results show that adding
bird
song or
rain
sound affects the participants’ perceptions, and the proxemic distances play a nonnegligible role. For instance, we found that participants liked the
bird
condition the most when the drone was at
far
, while they disliked the same sound the most when at
near
. We also found that participants’ perceptions strongly depended on their associations and interpretations deriving from previous experience. We derived six concrete design recommendations.
Community Mental Health Services for American Indians and Alaska Natives: Reconciling Evidence-Based Practice and Alter-Native Psy-ence
Authors: Gone Joseph P.
Published: January 2023

This review updates and extends Gone & Trimble's (2012) prior review of American Indian (AI) and Alaska Native (AN) mental health. First, it defines AI/AN populations in the USA, with an explanation of the importance of political citizenship in semisovereign Tribal Nations as primary for categorizing this population. Second, it presents an updated summary of what is known about AI/AN mental health, with careful notation of recurrent findings concerning community inequities in addiction, trauma, and suicide. Third, this article reviews key literature about AI/AN community mental health services appearing since 2010, including six randomized controlled trials of recognizable mental health treatments. Finally, it reimagines the AI/AN mental health enterprise in response to an “alter-Native psy-ence,” which recasts prevalent mental health conditions as postcolonial pathologies and harnesses postcolonial meaning-making through Indigenized therapeutic interventions. Ultimately, AI/AN Tribal Nations must determine for themselves how to adopt, adapt, integrate, or refuse specific mental health treatments and services for wider community benefit.
Localization and Detection of Multiple Attacks in Wireless Sensor Networks Using Artificial Neural Network
Authors: Gebremariam Gebrekiros Gebreyesus , Panda J. , Indu S.
Published: January 2023

Security enhancement in wireless sensor networks (WSNs) is significant in different applications. The advancement of routing attack localization is a crucial security research scenario. Various routing attacks degrade the network performance by injecting malicious nodes into wireless sensor networks. Sybil attacks are the most prominent ones generating false nodes similar to the station node. This paper proposed detection and localization against multiple attacks using security localization based on an optimized multilayer perceptron artificial neural network (MLPANN). The proposed scheme has two major part localization techniques and machine learning techniques for detection and localization WSN DoS attacks. The proposed system is implemented using MATLAB simulation and processed with the IBM SPSS toolbox and Python. The dataset is classified into training and testing using the multilayer perceptron artificial neural network to detect ten classes of attacks, including denial-of-service (DoS) attacks. Using the UNSW-NB, WSN-DS, NSL-KDD, and CICIDS2018 benchmark datasets, the results reveal that the suggested system improved with an average detection accuracy of 100%, 99.65%, 98.95%, and 99.83% for various DoS attacks. In terms of localization precision, recall, accuracy, and f-score, the suggested system outperforms state-of-the-art alternatives. Finally, simulations are done to assess how well the suggested method for detecting and localizing harmful nodes performs in terms of security. This method provides a close approximation of the unknown node position with low localization error. The simulation findings show that the proposed system is effective for the detection and secure localization of malicious attacks for scalable and hierarchically distributed wireless sensor networks. This achieved a maximum localization error of 0.49% and average localization accuracy of 99.51% using a secure and scalable design and planning approach.
Multiple Solutions of a
p
-th Yamabe Equation on Graph
Authors: Peng Zhongqi , Zhu Aimin , Zhang Tingting
Published: January 2023

Let

G
=

V
,
E

be a connected finite graph and

Δ

p

be the

p

-Laplacian on

G

with

p
>
1

. We consider a perturbed

p

-th Yamabe equation

−

Δ

p

u
−
λ

u

p
−
2

u
=
h

u

α
−
2

u
+
ε
f

, where

h
,
f
:
V
⟶
ℝ

are functions with

h
,
f
>
0

;

1
<
p
<
α
;

λ

and

ε

are two positive constants. Using the variational method, we prove that there exists some positive constant

ϵ

1

such that for all

ϵ
∈

0
,

ϵ

1

, the above equation has two distinct solutions.
HAV Infection Associated with Hemophagocytic Syndrome
Authors: Aamri H. , Elqadiry R. , Nassih H. , Bourrahouat A. , Ait Sab I.
Published: January 2023

Hemophagocytic syndrome is a rare disease that can cause severe illness and death. This condition is caused by the presence of antibodies against the hepatitis A virus. A positive anti-IGM antibody was identified in our 7-year-old patient with severe hepatitis A. A week after the hepatitis A was diagnosed, the patient experienced pancytopenia, which was worsened by prolonged fever. He was then diagnosed with macrophage activation syndrome. The treatment with steroids improved the clinical and biological evolution of the condition.
Perioperative Respiratory Outcome of Patients with Eosinophilia: A Cohort Study in a Tertiary Care Hospital
Authors: Lyngdoh Nari M. , Thabah Rajani , Aggarwal Sunny , Sailo Laltanpuii , Shakya Raju , Wahlang Julie , Shylla Badondor , Naskar Chhandasi
Published: January 2023

Background. A respiratory adverse event is one of the main causes of critical events in the perioperative period. Perioperative distress symptoms like cough and stridor have been reported to occur in patients with hyperreactive airways. Objective. This study was conducted to determine the relationship between blood eosinophil count and perioperative adverse respiratory events among different age groups of patients who require general anesthesia for different types of surgeries. Methods. A cohort study was conducted on 197 patients of either gender, aged 3 years and above, belonging to ASA classes I–II, who were scheduled to undergo surgery requiring general anesthesia and intubation. Patients were stratified according to absolute eosinophil count into two groups: Group A (AEC 0 to 499/mm3) and Group B (AEC 500 to 1000/mm3). Patients were monitored for 24 hours in the perioperative period for adverse respiratory events such as bronchospasm, laryngospasm, a fall in SPO2 < 95%, and cough and stridor. Results. A total of 197 patients were evaluated, with a median age of 37 ± 14.4 years. The percentage range of adverse respiratory events across different age groups was 35% in adults to 60% in children. Major complications noted were a fall in SPO2 < 95% (62.5%) and cough (27.7%) as per CTCAE v5.0 (November 27, 2017). The Naranjo score of adverse respiratory events was categorized as possible with mild level 1 severity. Adverse respiratory events were managed with humidified oxygen, antitussives, and bronchodilators. Conclusions. Eosinophilia is seen in one-third of the patients undergoing surgical interventions. Patients with a blood eosinophil count of ≥400/mm3 had an increased risk of exacerbations of respiratory adverse events in the perioperative period.
Oculogyric Crisis after Initiation of Aripiprazole: A Case Report of an Active Duty Service Member
Authors: Hadler Nicole L. , Roh Yevin A. , Nissan David A.
Published: January 2023

Introduction. Oculogyric crisis is an acute dystonic reaction characterized by sustained, bilateral, and upward deviation of the eyes. It is a relatively uncommon extrapyramidal side effect of antipsychotic medications. Aripiprazole is an atypical antipsychotic that is FDA-approved for the treatment of schizophrenia, bipolar disorder, Tourette’s disorder, and treatment resistant major depressive disorder. Compared to other antipsychotics, it is thought to have a lower propensity for causing dystonic side effects. Clinical Case. This case report is of a 19-year-old male who was psychiatrically hospitalized for first episode psychosis and initiated on low-dose oral aripiprazole. Three days after initiation of the medication, the patient was found to be markedly anxious and pacing around his room. Exam was notable for intermittent upward eye rolling, sustained upward conjugate gaze, and limited downward gaze. No other facial dyskinetic movements were observed. Treatment. The patient’s oral aripiprazole was held, and he was administered 50 mg of oral diphenhydramine with improvement in symptoms within one hour. Ocular symptoms, dizziness, frontal headache, and pacing were resolved the following morning. He declined reinitiation of an antipsychotic medication. Conclusion. Aripiprazole-induced acute dystonia, specifically OGC, is a rare potential adverse effect of aripiprazole. Risk factors include male gender, young age, use of typical antipsychotics, and initiation or uptitration of an antipsychotic. Even though atypical antipsychotics including aripiprazole are associated with lower risk for extrapyramidal symptoms, the possibility of oculogyric dystonia merits close monitoring especially in young, male, and drug naive patients. Anticholinergic agents such as diphenhydramine can treat symptoms of acute dystonia.
Cytology of Benign Peritoneal Fluids and Pelvic Washing Specimens: Diagnostic Cytomorphologic Features and Pitfalls
Authors: Yu Gordon H. , Song Sharon J.
Published: January 2023

Background: Pelvic washing and peritoneal fluid cytology specimens are used to detect peritoneal spread of malignancies. In most cases, identification of malignancy in these specimens is straightforward, but benign processes may occasionally mimic neoplasia and cause diagnostic difficulty. Summary: In this article, we perform a focused review of common benign entities encountered in pelvic washing and peritoneal fluid specimens during routine practice which may cause difficulty and discuss helpful features for avoiding diagnostic pitfalls. Key Messages: Application of strict cytomorphologic criteria, along with judicious use of ancillary studies and correlation with clinical, intraoperative, radiologic, and other pathologic findings, can help resolve most problematic cases.
Helicobacter pylori Reinfection Diagnosed by Endoscopic and Histologic Recurrence in a Patient with Gastric Mucosa-Associated Lymphoid Tissue Lymphoma
Authors: Sugiyama Toshiro , Nanjo Sohachi , Nakajima Takahiko , Kato Chieko
Published: January 2023

Helicobacter pylori infection is a major cause of gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Successful H. pylori eradication can induce a complete remission (CR); however, it takes a long time. In this case, the recurrence of gastric MALT lymphoma was observed by endoscopic and histologic findings during a 11-year follow-up and due to H. pylori reinfection twice. After the first successful eradication and achieving histologic CR, the patient was starting to work at a nursing home for older adults, where she frequently came in contact with their vomitus or feces. In the examinations 2 years later after the first successful eradication, endoscopic and histologic findings have demonstrated deterioration. Similar findings were continuously observed in the examinations 3 months later, and H. pylori reinfection was confirmed by the rapid urease test. After the second successful eradication, endoscopic and histologic CR of gastric MALT lymphoma was achieved. However, endoscopic and histologic findings have shown deterioration again 1 year later after the histologic CR and at 3.5 years later after the second successful eradication. H. pylori reinfection was confirmed by the repeated urea breath test, and the patient had received the third eradication treatment; and the patient had achieved successful eradication. In addition, proper hygiene practices were advised to avoid H. pylori reinfection. H. pylori reinfection is very rare in adults after successful eradication in developed countries. After successful eradication and proper hygiene practice, endoscopic and histologic CR has been maintained for 2 years up to the present.
Tradição, masculinidades e posições de sujeito: uma etnografia entre homens em Cabinda
Authors: Muller Paulo Ricardo
Published: January 2023

Neste artigo reflito sobre o papel da masculinidade como posição de sujeito entre interlocutores de uma pesquisa etnográfica sobre a noção de tradição Cabinda, província do norte de Angola, África central. Trata-se, nesse sentido, de um desdobramento da análise dos resultados da pesquisa a partir de questionamentos provenientes dos estudos de gênero e feministas. Parto do entendimento de que o conjunto de relações de pesquisa que se estabelece com pessoas, lugares e ideias no processo de inserção em um determinado contexto sociocultural direciona a pesquisa a enxergar e problematizar determinadas questões, e outras não, a respeito daquele contexto. Partindo do pressuposto de que a situação etnográfica é construída mutuamente entre pesquisador e interlocutores, busco, com esta reflexão, identificar correlações entre alguns elementos da descrição etnográfica da pesquisa em Cabinda e diferentes modos de construção de masculinidades descritos pelo referencial antropológico e dos Estudos Africanos.
Um preto doutor
Authors: Alves Daniel Cardoso
Published: January 2023

Texto poético
De peixe a humano: Metamorfoses e interações entre animais e humanos em duas narrativas da obra Murũgawa
Authors: Nascimento Marina Almeida Simões do
Published: January 2023

A partir de duas histórias breves, publicadas no livro Murũgawa (2007), de Yaguarê Yamã, analisamos como o pensamento indígena sobre o mundo se revela tanto no enredo quanto na forma de narrar essas histórias. Na obra, voltada ao público juvenil, as interações e metamorfoses mostram como os indígenas veem os animais: como seres espiritualizados e com subjetividade própria. Esta leitura apoia-se nos estudos literários e na antropologia, sobretudo na teoria do perspectivismo ameríndio.
A memória e a construção da identidade negra no romance angolano Esse cabelo, de Djaimilia Pereira
Authors: Gonçalves Rute Lages , Mendes Algemira de Macêdo
Published: January 2023

O artigo intitulado “A memória e a construção da identidade negra no romance angolano Esse cabelo, de Djaimilla Pereira, busca analisar no romance, o papel da memória para construção da identidade angolana da personagem Mila, a fim de entender a importância das lembranças da infância na sua construção identitária como mulher negra.
Negatividade e fracasso em Cassandra Rios: repensando afetos queer
Authors: Resende Marcelo Branquinho Massucatto
Published: January 2023

Partindo da fortuna crítica sobre a escritora Cassandra Rios, analiso, com base na fenomenologia queer de Sara Ahmed (2006) e a crítica de Heather Love (2007) sobre as genealogias da história LGBTQIA+, possibilidades de reelaborar percepções passadas, bem como o passado literário e pessoal da escritora lésbica Cassandra Rios. O intuito é encarar as faltas e elementos problemáticos presentes nos romances da autora, muitas vezes deixados de lado pelos estudos cassandrianos, de modo a enfocar as faltas e a negatividade queer presente na escrita de Cassandra Rios. Com isso, espera-se abrir caminho para pensar novas possibilidades e pistas para enxergar um elemento chave da história lésbica e LGBTQIA+ brasileira.
A atmosfera afetiva de um criptandro
Authors: Silva Ruan Nunes
Published: January 2023

Buscando teorizar o que é uma atmosfera afetiva, o presente trabalho analisa alguns afetos no romance Eu sou uma lésbica, de Cassandra Rios. Ao destacar o medo, o nojo e o prazer como parte da atmosfera afetiva da protagonista Flávia, destacam-se as formas nas quais essas emoções são empregadas para mobilizar sentidos no mundo. Para a discussão, o artigo traz à baila principalmente os apontamentos teórico e críticos de Sara Ahmed (2014) e Claudia Barcellos Rezende e Maria Claudia Coelho (2010).
Heterossexualidade compulsória e protagonismo lésbico no romance Controle, de Natalia Borges Polesso
Authors: Silva Eliane Santos da , Jardim Nadege Ferreira Rodrigues
Published: January 2023

Esse artigo tem como objetivo analisar como a heteronormatividade se evidencia e influencia a experiência individual das duas personagens lésbicas: a protagonista-narradora Maria Fernanda/Nanda e sua amiga de infância Joana no romance de formação Controle (2019), de Natalia Borges Polesso. A concepção de Humanidade é construída sobre classificações binárias que se fazem por exclusão, “normalidade” e “anormalidade” estão presentes no percurso individual da protagonista-narradora que é marcado pelas diversas tecnologias de dominação e opressão que regulam e atravessam não somente as lésbicas, mas todas as vidas relegadas ao lugar/papel do “outro”. Como aporte teórico serão utilizados os conceitos de Heterossexualidade compulsória, de Adrienne Rich (2010), The Straight Mind, de Monique Wittig (1980) e Epistemologia do armário, de Eve K. Sedgwick (2007).
Representações de lesbianidade noromance maranhense Uma sombrana parede, de Josué Montello
Authors: Lucena Saulo da Silva , Oliveira Rubenil da Silva
Published: January 2023

O artigo analisou a lesbianidade no romance maranhense Uma sombra na parede (1995),de Josué Montello. A pesquisa foi do tipo bibliográfica, exploratória e explicativa. Fundamentado emBeauvoir (1980), Foucault (2007) e outros. Portanto, o narrador demonstrou, no romance, a visãoultraconservadora com que a sociedade maranhense notava a mulher lésbica, baseada nosdiscursos de poder e controle sobre os corpos, inclusive o bíblico/ religioso.
Nos rastros de Ruth Ducaso: linguagem e liberdade nos livros de Luciany Aparecida
Authors: Polesso Natália Borges
Published: January 2023

Este ensaio tenta capturar um fragmento de Ruth Ducaso, escritora ficcional, assinatura estética de Luciany Aparecida. Procuro explicitar o que é uma assinatura estética, de acordo com a autora, e quem é Ruth Ducaso, bem como, comentar e analisar seus livros à luz das discussões sobre colonialidade e gênero.
Apartheid na Palestina: do debate internacional ao seu reconhecimento e julgamento. Entrevista com o ex-relator especial designado pelo Conselho de Direitos Humanos da ONU, John Dugard
Authors: Bacila Sahd Fábio
Published: January 2023

Dentre outras coisas, nesta entrevista John Dugard versa sobre a tipificação de apartheid e seus vínculos com o colonialismo, a legalidade dos movimentos palestinos de resistência, a atuação dos diferentes relatores especiais designados pelo CDH-ONU e compara o caso sul-africano e israelense, assim como sua interpretação do apartheid israelense (restrita aos TPO) com aquela contida na bibliografia e em outros relatórios, atinente ao território como um todo. Ainda, comenta sobre suas expectativas quanto ao processo movido contra o Estado de Israel pelo Estado da Palestina no Tribunal Penal Internacional que, em 2021, reconheceu ter jurisdição sobre o caso.
Representações Sociais dos profissionais de saúde relativas ao trabalho no período de pandemia da Covid-19
Authors: Sanches Leide da Conceição , Moliani Maria Marce , Santos Claudia Rejane Schavarinski Almeida , Schwyzer Ingrid
Published: January 2023

O presente estudo buscou apreender as representações sociais dos profissionais de saúde em seu processo de trabalho durante o período de pandemia da Covid-19. Essa pesquisa foi realizada no período de setembro de 2020 a fevereiro de 2021, portanto, anterior ao início da vacinação. Para coleta dos dados foi utilizado um formulário desenvolvido no Google Forms. Responderam ao questionário 197 participantes, de diversas áreas da saúde, que no primeiro período da pandemia trabalhavam em atendimento direto ao Covid-19. Para a organização dos dados se fez uso da interface visual ancorada na linguagem R e Python, Iramuteq, facilitando a identifi cação de padrões lexicais e ligações entre diferentes termos presentes em um conjunto de textos, a partir do que se elegeu três categorias de análise: medo, insegurança e isolamento, que orientaram a estrutura da análise e discussão. Conclui-se que medo, insegurança e isolamento são recorrentes na história das epidemias, porém, são ressignifi cados a cada contexto, como na pandemia da Covid-19, conforme suscitados pelos/as participantes da pesquisa.
Transmissão pessoa a pessoa: análises sociológicas da pandemia COVID-19
Authors: Pingel Emily , Pinhel André Marega
Published: January 2023

Apresentação do dossie Transmissão pessoa a pessoa: análises sociológicas da pandemia COVID-19.
A Tradição Gótica no jogo eletrônico Until Dawn
Authors: Aguiar Iris Maitê Fullas
Published: January 2023

O presente artigo tem como objetivo principal analisar o enredo do jogo eletrônico Until Dawn (2015) pelo prisma da tradição Gótica. Considerando as colocações de Rossi (2008), procuram-se evidenciar os principais elementos narrativos que estabelecem um diálogo com o Gótico. A análise tem como base os três elementos basilares apresentados por França (2016): o locus horribilis, a personagem monstruosa e a presença fantasmagórica do passado. Além disso, tomando os estudos de Murray (2003), Wolf (2001), Perron (2004) e Aarseth (2004) em termos de estudos de narratologia e jogos, o artigo pretende demonstrar como as escolhas feitas pelo jogador são exploradas com a finalidade de intensificar sua experiência narrativa e explorar os elementos do gótico presentes no enredo.
A duplicação em José Saramago
Authors: Diniz Moema Najjar
Published: January 2023

Este artigo analisou o tema da duplicação das personagens do romance alegórico O homem duplicado, de José Saramago à luz de teóricos críticos da sociedade atual, de consumo/líquido-moderna para Bauman e do desempenho para Byung-Chul Han. Por meio da ficção, o escritor encena o esfacelamento da singularidade, a aniquilação da identidade e a transformação de pessoas mercadoria, colocando em xeque os valores e desafios trazidos pelo capitalismo.
O diálogo e a exposição em duas dunas
Authors: Silva Marvin Kenji Nakagawa e
Published: January 2023

O presente artigo tem como objetivo analisar e comparar as duas adaptações de Duna (1984) de Frank Herbert para o cinema, observando as especificidades de cada obra. Para isso, faz-se necessário três eixos como substrato teórico: os estudos da adaptação, os estudos cinematográficos e os estudos literários, visto que, analisaremos cada narrativa considerando sua própria autonomia. Nesse sentido, objetivamos entender as razões pelas quais a primeira adaptação não alcançou os resultados esperados, enquanto, a mais recente, obteve sucesso.