bluuebunny/crossref_metadata_2025 huggingface dataset:
Financial and instrumental support for adult children and depressive symptoms among older adults in China: Does gender make a difference?
Authors: Deng Yuanping , Chen Li , Chen Meizhu , Liu Jia , Li Yu
Published: September 2023

For this study we used the demographic data of 5,669 Chinese adults aged between 60 and 79 years, drawn from the 2018 China Family Panel Studies. The propensity score matching method was used to analyze the effect of providing financial and instrumental support for adult sons and daughters
on the depressive symptoms of parents. We also tested for gender differences in this effect. The results showed that providing financial support was significantly associated with greater risk of depressive symptoms in men but not in women. By contrast, providing instrumental support reduced
the risk of depressive symptoms in both men and women. These findings suggest that adult children should reduce their financial dependence on their parents and that parents should be encouraged to help their adult children by carrying out suitable instrumental support, which could promote
parent???child communication and reduce risk of depressive symptoms in older adults.
THE EFFECT OF DENTAL IMPLANTS ON AEROBIC BACTERIA COLONIZATION IN THE ORAL CAVITY AND THE ANTIBIOTIC PROFILE OF COMMON ISOLATED AEROBIC BACTERIA
Authors: Al-Hamzi Mohsen Ali , Sharafuddin Abeer Hasan , Al-Shameri Basheer Hamed Hamood , AL-Haddad Khaled A , Al-Najhi Mohammed Ali , Al-Shamahy Hassan Abdulwahab , Al-Moyed Khaled Abdulkarim
Published: September 2023

Background and aims: The mouth's microflora may alter as a result of dental implants. The purpose of this study was to examine the composition of aerobic bacteria in patients with dental implants and those who had natural teeth (without implants) as well as the response of those bacteria to antibiotic treatment.
Methods: Bacteriological tests were performed on 72 patients (36 dental implants and 36 natural teeth) who visited dental clinics run by Sana'a University's Faculty of Dentistry and private dental clinics. Antibiotic susceptibility tests and culture trials were carried out at the National Center for Public Health Laboratories (NCPHL) in Sana'a, Yemen. Swabs were taken from the mucous membrane of the palate and the dorsum of the tongue from both groups, and cultured on selective and non-selective solid medium, in addition to culturing the swabs on medium enriched with 5% blood, then all cultured plates were incubated to microaerophilic conditions (5% CO2) and oxygenated in 37oC for 48 hours. Then bacterial growth was identified by standard methods.
Results: In implant patients, the rate of bacterial isolates from the palate and tongue was slightly higher for potentially harmful bacteria such as E. coli (8.3% in tongue implant patients vs. 2.8% in non-implant patients) and Pseudomonas aeruginosa (5.6% versus 0%). While in viridians Streptococcus including S. mutans, there was a higher colonization rate in implants patients (83.3% in the palate verses, 75% in the palate of individuals without implants). A low level of oxacillin resistance (5.1%) in S. mutans isolates but S. mutans had a substantial level of tetracycline resistance (55.93%), 11.9% for co-trimoxazole, 10.2% for erythromycin, and just 1.7% for clindamycin.
Conclusion: The study found that pathogenic bacteria like E. coli and Pseudomonas aeruginosa were isolated from the palate and the back of the tongue swabs at a slightly elevated rate in implant patients; also colonization rates of Streptococcus viridians, including S. mutans, were higher in implant patients compared to those without implants. There was a significant levels of antibiotics resistance in S. aureus, CoNs and S. viridians oral isolates in both groups of tested individuals. 
                        
Peer Review History:
Received: 14 June 2023; Revised: 13 July; Accepted: 17 August, Available online: 15 September 2023
Academic Editor: Dr. A.A. Mgbahurike, University of Port Harcourt, Nigeria, amaka_mgbahurike@yahoo.com
Received file:                             Reviewer's Comments:
Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 8.0/10
Reviewers:
Dr. Rola Jadallah, Arab American University, Palestine, rola@aauj.edu
Dr. Bilge Ahsen KARA, Ankara Gazi Mustafa Kemal Hospital, Turkey, ahsndkyc@gmail.com
ACETYLCHOLINESTERASE INHIBITION, NOOTROPIC AND ANTIOXIDANT EFFECT OF EXTRACTS FROM AGAVE SPECIES
Authors: Maribel Herrera-Ruiz , Enrique Jiménez-Ferrer , Alejandro Zamilpa , Ruperto Jiménez-Aparicio Antonio , Lucía Arenas-Ocampo Martha , Nayeli Monterrosas-Brisson
Published: September 2023

Background: The systemic administration of Lipopolysaccharide (LPS) is a pharmacological model to evaluate different processes associated with neurodegeneration; it is capable of causing an increase in the oxidative state in the brain and increasing the activity of the enzyme acetylcholinesterase (ACh-E), involved in the degradation of acetylcholine (ACh). This cholinergic transmission system participates in memory processes, a crucial symptom in neurodegenerative disorders, and its modulation with scopolamine turns out to be an essential tool in the evaluation of plants. Species of the genus Agave are considered a natural resource of economic and cultural importance in Mexico. They possess compounds with anti-inflammatory, antioxidant, and anti-neuroinflammatory activities.
Methods: Extracts of A. tequilana (At-A), A. angustifolia (Aan-A), A. americana (Aam-A) at 125 mg/kg were administered to male ICR mice with LPS to evaluate the ACh-E inhibition, the concentration of the antioxidant enzyme Gluthatione Reductase (GR) and the prooxidant enzyme NADPH Oxidase (NOX). Also, the nootropic effect of these extracts on scopolamine-induced cognitive impairment was evaluated.
Results: The three Agave species studied decreased the ACh-E enzyme activity, Vmax value, and KM. These products increased the GR concentration from 0.173±0.003 (vehicle) to 0.642±0.002 µMol/mg in At-A, which was the highest one. Regarding NOX, only the A. tequilana extract decreased it (0.513±0.002µMol/mg)compared with Vehicle (0.621±0.008µMol/mg). A. tequilana and A. americana species significantly improved the retention latency parameter (260 seconds) during the passive avoidance test.
Conclusion: Agave species showed promising results in developing novel drugs for neurodegenerative disease therapy.
                       
Peer Review History:
Received: 17 June 2023; Revised: 22 July; Accepted: 27 August, Available online: 15 September 2023
Academic Editor: Dr. Asia Selman Abdullah, Pharmacy institute, University of Basrah, Iraq, asia_abdullah65@yahoo.com
Received file:                             Reviewer's Comments:
Average Peer review marks at initial stage: 5.5/10
Average Peer review marks at publication stage: 7.0/10
Reviewers:
Dr. Sangeetha Arullappan, Universiti Tunku Abdul Rahman, Malaysia, sangeetha@utar.edu.my
Prof. Ali Gamal Ahmed Al-kaf, Sana'a university, Yemen, alialkaf21@gmail.com
Electromyographic Activities of Pectoralis Major and Triceps Brachii Muscles During Push-Up Exercises On Different Surfaces
Authors: AYDIN Erbil Murat , GÜNDOĞAN Burak , SAĞLAM Ali Fatih
Published: September 2023

The push-up is a basic exercise commonly used in strength training. This exercise can be performed on different surfaces. The purpose of this study is to compare the muscle activation of the pectoralis major and triceps brachii muscles during push-up exercises performed on stable and unstable surfaces. Nineteen males participated in this study. Bosu ball and ring apparatus were used as unstable surfaces and the floor was used as a stable surface. Subjects performed 5 repetitions of PU on the different surfaces. A one-way repeated-measures analysis of variance was used to compare the muscle activities between the surfaces. Muscle activation of PM was significantly greater in the ring than on the floor and the Bosu ball (p0.05). In conclusion, using the ring apparatus as an unstable surface increase the PM muscle activation in PU exercise. Muscle activation of TB was not influenced by surface stability in PU.
Analisis Kepuasan Tamu Terhadap Kualitas Pelayanan Karyawan Kantor Depan
Authors: Putra Putu Arya Krisna Adi , Ismail Deden , Suwintari I Gusti Ayu Eka
Published: September 2023

The Ritz – Carlton Bali merupakan salah satu hotel bintang 5 yang terletak di Sawangan Nusa Dua , Badung, Bali. Terdapat 2 masalah yang ditemukan di penelitian ini yaitu bagaimana kualitas pelayanan kantor depan terhadap kepuasan tamu dan upaya – upaya yang dilakukan untuk meningkatkan kualitas pelayanan. Penelitian ini juga ditunjukkan untuk menganalisis kepuasaan tamu terhadap pelayanan karyawan kantor depan. Jenis data yang digunakan adalah data kuantitatif. Sumber data pada penelitian ini menggunakan data primer dan sekunder. Semua data tersebut dikumpulkan dengan metode kuesioner yang diberikan langsung kepada tamu. Kemudian data tersebut diukur dengan metode Servqual menurut Supranto (2011). Dalam penelitian ini yang data dianalisis menggunakan teknik analisis uji reliabilitas, uji validitas, dan Diagram Kartesius. Berdasarkan hasil penelitian kepuasan tamu yang diperoleh dari rata-rata kinerja pada angka 0,02 dimana nilainya lebih besar dari 0 menunjukkan kepuasan tamu sangat tinggi. Berdasarkan pembahasan tersebut dapat disimpulkan bahwa tingkat kepuasan tamu sangat tinggi yang didasarkan pada pelayanan yang diberikan oleh karyawan , namun masih ditemukan beberapa indikator tamu merasa kurang puas dengan pelayanan yang diberikan karyawan , hal ini karena karyawan kantor depan belum maksimal dalam memberikan pelayanan terhadap apa yang tamu anggap sangat penting. Dengan hal tersebut maka pihak hotel melakukan beberapa upaya sebagai dasar untuk meningkatkan kualitas pelayanan tamu pada kantor depan Hotel The Ritz -Carlton Bali.
 
The Ritz – Carlton Bali is a 5 star hotel located in Sawangan Nusa Dua, Badung, Bali. There are 2 problems found in this study, namely how the quality of front office services to guest satisfaction a nd the efforts made to improve service quality. This study was also shown to analyze guest satisfaction with the service of front office employees. The type of data used is quantitative data. Sources of data in this study using primary and secondary data. All of the data was collected by using a questionnaire method which was given directly to the guests. Then the data was measured by the Servqual method according to Supranto (2011). In this study, the data were analyzed using reliability test analysis techniques, validity tests, and Cartesian diagrams. Based on the results of guest satisfaction research obtained from the average performance at 0.02 where the value is greater than 0 indicates very high guest satisfaction. Based on the discussion, it can be concluded that the level of guest satisfaction is very high based on the services provided by employees, but there are still some indicators that guests feel dissatisfied with the services provided by employees, this is because the front office employees have not been maximal in providing services to what guests consider very important. With this, the hotel made several efforts as a basis for improving the quality of guest service at the front office of The Ritz-Carlton Bali Hotel.
Kualitas Abon Vegetarian Berbahan Dasar Bonggol Pisang Klutuk
Authors: Dewi Ida Ayu Ari Chandra , Lestari Denok
Published: September 2023

Abon merupakan makanan yang tidak asing lagi dikonsumsi oleh masyarakat Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui kualitas abon vegetarian berbahan dasar bonggol pisang klutuk melalui eksperimen uji organoleptik dari segi rasa, warna, tekstur dan aroma, kemudian untuk mengetahui daya tahan , minat konsumen serta untuk mengetahui biaya produksi dari produk abon vegetarian berbahan dasar bonggol pisang klutuk. Adapun metode penelitian yang digunakan pada penelitian ini adalah metode penelitian eksperimen dengan teknik pengumpulan data menggunakan kuantitatif dan kualitatif. Hasil dari penelitian ini berdasarkan uji organoleptik yang dilakukan oleh 20 panelis memperoleh hasil enak dari segi rasa, menarik dari segi warna, kering dari segi tekstur dan sangat harum dari segi aroma. Dari uji daya tahan abon vegetarian berbahan dasar bonggol pisang klutuk, mampu bertahan selama 7 hari. Hasil survey minat konsumen menunjukkan masyarakat tertarik dengan inovasi produk abon ini. Hasil analisis biaya satu kali produksi abon adalah Rp 32.575,- serta biaya untuk satuan produk dengan berat 100 gram/ bungkus adalah Rp 16.300.
 
Abon or Floss is a food that is familiar consumed by the people of Indonesia. The purpose of this study was to determine the quality of vegetarian floss klutuk banana hump through organoleptic testing in terms of taste, color, texture and aroma, then to determine durability, consumer interest and to determine the production cost of vegetarian floss made of klutuk banana hump. The research method used in this study is an experimental research method with data collection techniques using quantitative and qualitative. The results of this study based on organoleptic tests conducted by 20 panellists obtained good results in terms of taste, attractive in terms of colour, dry in terms of texture and very fragrant in terms of scent. From the resistance test the vegetarian floss klutuk banana hump was able to last for 7 days. The results of the consumer interest survey show that people are interested in this floss product innovation. The result of the one-time cost analysis is Rp 32.575, - and the unit price with a weight of 100 grams/pack is Rp 16,300.
Pengaruh Penggunaan Puree Labu Kuning Terhadap Kualitas Kulit Dimsum
Authors: Friets Hans , Wardana Miko Andi
Published: September 2023

Dimsum adalah kudapan yang terbuat dari tepung terigu dan tepung kentang yang menjadi bahan utama dalam pembuatan kulit dan isian yang biasanya menggunakan paha ayam ataupun udang, proses pembuatan dimsum sama saja pada dasarnya sehingga yang membedakan hanya isian yang terdapat dalam dimsum itu sendiri.dalam mengatasi persamaan pada kualitas dimsum ini diperlukan alternatif lain seperti mengganti bahan atau mencampur bahan baku dengan bahan lain, Daging labu kuning mempunyai nilai gizi yang tinggi, sehingga dapat digunakan sebagai bahan tambahan dalam membuat suatu produk makanan. Tujuan yang dicapai pada penelitian ini adalah apakah daging labu kuning dapat dijadikan alternatif sebagai bahan campuran dengan tepung terigu, tepung maizena,tepung tapioka dan tepung kentang dalam pembuatan kulit dimsum. Hasil penelitian adalah (P0) dengan menggunakan 25% Daging labu kuning yang paling banyak disukai oleh panelis diperoleh dari skor yang berasal dari perhitungan kuesioner yang telah dibagikan yang ditinjau dari aspek: Warna, Aroma, Tekstur, Rasa.
 
Dimsum is a snack made from wheat flour and potato flour which are the main ingredients in making the Wrapper and the filling which usually uses chicken or shrimp thighs, the process of making dimsum is basically the same so that the only difference is the stuffing inside. dimsum itself. This dimsum quality equation requires other alternatives such as replacing ingredients or mixing raw materials with other ingredients. Pumpkin meat has a high nutritional value, so it can be used as an additional ingredient in the manufacture of a food product. This study aims to determine whether pumpkin flesh can be used as an alternative to a mixture of wheat flour, cornstarch, tapioca flour and potato flour in the manufacture of dimsum Wrapper. The results of the study were (P0) using 25% pumpkin flesh which was the most preferred by the panelists, obtained from the scores obtained from the calculation of the questionnaire that had been distributed in terms of aspects: Color, Aroma, Texture, Taste.
Kualitas Sari Jahe Sebagai Bahan Pembuatan Puding
Authors: Wijaya Pande Made Krisna Angga , Mariani Ni Wayan Rena
Published: September 2023

Puding merupakan hidangan penutup yang banyak digemari orang dimana hidangan ini memiliki tekstur kenyal dan rasa yang manis. Puding pada umumnya terbuat dari susu dan bahan pengental seperti gelatin, bubuk agar- agar, kuning telur serta bahan lainnya. Tujuan dari penelitian ini adalah untuk mengetahui kualitas puding dengan penambahan sari jahe yang dinilai dari segi warna, aroma, rasa dan tekstur. Jahe merupakan salah satu tanaman rempah yang memiliki khasiat yang baik bagi kesehatan tubuh karena menjadi salah satu rempah yang memiliki kandungan antioksidan. Selain itu jahe juga memiliki minyak atsiri yang berkhasiat untuk mencegah dan mengobati berbagai penyakit. Jenis penelitian ini adalah penelitian eksperimen, dengan sumber data yang digunakan adalah data primer dan data sekunder. Metode pengumpulan data yang dilakukan adalah dengan mekanisme kuisioner dan observasi. Hasil dari penelitian yang sudah dilakukan menunjukan bahwa puding jahe memiliki warna yang Menarik, aroma yang Kuat, Rasa yang Enak serta tekstur yang Lembut. Dan daya tahan puding jahe yang disimpan pada lemari pendingin bertahan selama 1 minggu.
 
Pudding is a dessert that many people like where this dish has a chewy texture and a sweet taste. Puddings are generally made from milk and thickening agents such as gelatin, gelatin powder, egg yolks and other ingredients. The purpose of this study was to determine the quality of pudding with the addition of ginger juice which was assessed in terms of color, aroma, taste and texture. Ginger is one of the spice plants that has good properties for the health of the body because it is one of the spices that contains antioxidants. In addition, ginger also has essential oils that are efficacious to prevent and treat various diseases. This type of research is experimental research, with the data sources used are primary data and secondary data. The data collection method used is a questionnaire and observation mechanism. The results of the research that has been done show that ginger pudding has an attractive color, strong aroma, delicious taste and soft texture. And the durability of the ginger pudding stored in the refrigerator lasts for 1 week.
The trophic strategy of the European honey buzzard Pernis apivorus during breeding: extravagant specialization or genius solution?
Authors: Martín-Ávila Jorge Ángel , Rebollo Salvador , Fernández-Pereira José M. , Díaz-Aranda Luisa
Published: September 2023

The study of the diet of extreme specialist species can help to
understand the selective pressures that modulate the trophic strategies
of raptors. This article provides insight into the trophic strategy of a
little-known top predator and allows for a better understanding of the
selective pressures that shape its diet. We studied the diet of European
honey-buzzards, a raptor specialized in the consumption of social wasp
brood. The ratio of predator to prey biomasses is one of the highest
among raptors. We studied some factors that affect the energy demand of
pairs which influence the diet composition and the daily rate of prey
delivery to the nest. We explore hypotheses about the role of native and
exotic vespids in the diet and the influence of the number and age of
nestlings on diet composition, daily rate of prey delivery, and size of
combs delivered. We installed trail cameras in 24 honey-buzzards nests
in north-western Spain in 2018-2021. We estimated the proportion and
daily rate of delivery of native common-wasps (Vespula vulgaris),
invasive Asian-hornets (Vespa velutina), reptiles, and birds and the
honey-buzzard´s preferences for vespid species. We performed LMMs,
GLMMs, and MLRMs to analyse relationships between response variables and
predictors. We identified 4611 prey. Honey-buzzards mainly consumed
vespids (82% of prey). Common-wasps and Asian- hornets were almost the
only two vespids consumed. The invasive hornet was the second most
important prey consumed, but common-wasps were preferred. Vespids were
more important as the age and number of nestlings increased. Our results
suggest that the honey-buzzard´s diet is the adaptive result of the
conflict between being a median-sized insect-eating migratory nidicolous
raptor and collecting enough morsels for the growth of its nestlings,
supporting the prey size and ingestion rate hypothesis. We discuss
implications of our findings for the management of the invasive wasp
A CUP1-tag mediated approach for multi-copy gene integration in budding yeast
Authors: J. Yuan, , Song Jingya , Fan Cong , He Nike , He Kaiyuan , Ye Xixi
Published: September 2023

Saccharomyces cerevisiae, a generally recognized as safe (GRAS)
microorganism, is regarded as an industrial workhorse for chemical and
recombinant protein synthesis. In the biotechnological industry,
multi-copy gene integration represents an effective strategy to maintain
a high-level production of recombinant proteins-of interest, and to
assemble multi-gene biochemical pathways. In the present study, we first
created a copper-sensitive yeast strain by abolishing the CUP1
gene (encoding metallothionein that binds copper ions). Subsequently, we
harnessed the CUP1 as a selection marker and combined the δ sites
for multi-copy gene integration in S. cerevisiae. With the newly
developed CUP1-tagging platform, multi-copy chromosomal integration of
enhanced green fluorescent protein (eGFP) expression cassette was
achieved, and the engineered strains remained quite stable after
successive rounds of passaging. Taken together, we envision that the
CUP1-tagging system would be a robust and useful method for protein
overproduction and metabolic engineering applications in budding yeast.
Solidification of heavy metal elements in waste phosphate acid activated metakaolin geopolymer with environmental and economic benefits
Authors: Wang Kaibao , Wei Qingxin , Chen Hongwei , Le Huirong
Published: September 2023

This paper investigates the feasibility of using industrial waste acid
to prepare geopolymer with significant environmental and economic
benefits. Two types of waste acid were examined to discuss the effect of
waste acid content on the microstructure, mechanical performance,
thermal stability and heavy metal solidification efficiency. The core
issue solved in this investigation is the harmless treatment of
industrial waste acid and solidification efficiency of heavy metals, so
as to reduce the pollution of heavy metals on the environment and the
urgent demand for low carbon emissions in the construction and ceramic
industries. The results showed that the metal elements (Ag, Fe, Mo, Cu
and Ni) can be successfully solidified with over 95% solidification
efficiency, indicating that the geopolymers are appropriate for
hazardous material stabilisation, and the leaching of the heavy metals
to the environment can be well controlled. The environmental and
economic analysis indicates that the carbon and energy consumption
intensity were reduced by 92.7% and 77.9%, respectively, compared to
cement. What is more important is that the cost intensity is negative
due to the income of waste acid treatment, meaning that additional value
benefit was added to the product. This paves a promising way for the
low-carbon transformation of ceramic enterprises and industrial waste
treatment enterprises, drives further breakthroughs in high-tech
industries, and promotes the sustainable development of the local
national economy.
Implementing Screening for Eating Disorders in Adolescents and Young Adults with a History of Cancer
Authors: Kamat Aarti , Huysse Jessica Van , Walling Emily
Published: September 2023

Background Eating disorders are prevalent in the adolescent and
young adult population, with 2.7% of adolescents effected. The American
Academy of Pediatrics recommends yearly screening for eating disorders
in adolescents. Even with this recommendation, eating disorders often go
underdiagnosed. AYAs with cancer possess several risk factors for eating
disorders that may place them at an even higher risk, including
receiving weight-altering therapies and having their weight/nutrition
emphasized. Since these patients see their oncology team frequently,
oncology clinics are opportune settings for eating disorder screening.
This describes a single-institution study to implement screening for
eating disorders in AYA patients in an oncology clinic.
Procedures During regularly scheduled oncology visits, eligible
patients were given the SCOFF questionnaire. Patients with an oncologic
diagnosis aged 13 and older were screened. Patients with known eating
disorders and patients receiving cytotoxic therapy were excluded. The
questionnaire was scored by a study team member. Patients with a
positive screening were referred to adolescent medicine.
Results 163 eligible patients filled out the SCOFF
questionnaire with 11 positive results (6.75%). Conclusions
Our results demonstrate that eating disorder screening was successfully
implemented in our pediatric oncology clinic. With a rate more than
double than the general population, we observed that AYA patients with a
history of cancer are indeed at a higher risk for eating disorders and
should undergo routine screening. Since these patients have frequent
oncology appointments, oncology clinics should implement screening for
eating disorders. Further studies are needed to develop appropriate
screening methods for on therapy patients.
In silico investigation of MAPK1 mediated key protein interactors in lung squamous cell carcinoma
Authors: Ambreen Fareeha , Shah Zafar Abbas , Ejaz Rabea
Published: September 2023

MAPK1 signaling pathway promotes development and survival of epithelial
tissue. MAPKs family controls the activity of microenvironment by
triggering the intracellular signaling. Present study was designed to
understand the MAPK1 PPI by using STRING database and retrieve top
twenty interaction network to analyze the significance of MAPK1 related
proteins in lung Squamous cell carcinoma (SqCC). A cancer platform,
cBioPortal was used to perform gene alteration analysis to uncover their
participation in lung SqCC progression. TP53 gene showed high ratio
alteration among eleven lung SqCC linked disease causing MAPK1 mediated
pathway genes in comparative study of lung squamous cell carcinoma TCGA,
nature 2012 dataset. In present study, using meta-analysis, it has been
characterized that vital MAPK1 signaling pathway altered interactions
that are MYLK, BCL2, TP53, BCL6, RAF1, CTTN, FGF19, FGF3, FGF4, ATR,
TP63, HES1, CDKN2A, RASA, MRAS, TNFSF10, IL12A, TEK, PTEN, AGTR1, DVL3,
EPHB1, TRIO, RPS6KA1, RPS6KA2, FOS, FGFR1, PAK2, PRKCI, PIK3CA, PIK3CG
and KDR. These are involved in cell proliferation, growth,
differentiation, tumor suppressed activities and apoptosis. In aberrant
conditions they act as oncogenic and anti-apoptotic agents. The
empirical validation of MAPK1 signaling cascade key interactions in lung
SqCC may give fruitful selection of therapeutic targets for squamous
cell carcinoma in future.
Exploring gut microbiota diversity in Catharsius molossus: influence of dietary conditions on ecosystem functionality
Authors: Mao Yue , Yang Xingjian , Yuan Hui , Xiong Tao
Published: September 2023

Dung beetle serve as valuable indicators for studying environmental
changes and as model systems for exploring ecosystem functionality. By
analyzing the diversity and composition of gut microbiota in Catharsius
molossus under starvation and refeeding conditions, this study
investigates the effects of dietary states on the gut microbiota of
these insects. Artificial rearing methods, along with 16S rRNA
high-throughput sequencing and bioinformatics, were used to analyze
Catharsius molossus gut microbiota under varying dietary conditions. The
results indicate that at the phylum and genus levels, the gut microbiota
of Catharsius molossus under refeeding conditions is more diverse than
that under starvation conditions, with seven phyla and twenty-two genera
showing significant differences (P < 0.05). In terms of
functional prediction, the predicted functional genes of the gut
microbiota were annotated to the KEGG database, revealing significant
differences in thirty-two metabolic pathways at the third level (P
< 0.05). Furthermore, it provides functional prediction
information related to specific microbial taxa. Additionally,
Dysgonomonas is speculated to participate in nitrogen fixation, and the
gut microbiota of Catharsius molossus may potentially serve as a source
of antimicrobial agents like anshanmycin. These findings provide novel
insights into Coleoptera ecosystem microbial interactions and offer
theoretical support for future applications.
Learning Cataloguing and Classification: Is It on Popular Massive Open Online Courses (MOOC) Platforms?
Authors: Adetayo Adebowale
Published: September 2023

The paper explores if cataloguing and classification (CAT/CLASS) can be learnt on popular MOOC platforms and what can be done if nonexistent. Different MOOC platforms were explored with a concentration on EdX and Coursera. Literature on MOOCs was examined, and findings were reported. It was observed that some library science courses are available on MOOC platforms. However, no CAT/CLASS courses are available on EdX or Coursera. The majority of their library science courses did not cover the technical service aspects of librarianship. As a result, recommendations were made on how library stakeholders can play proactive roles in introducing CAT/CLASS to MOOC platforms. This is one of the first papers to examine the subject of CAT/CLASS on MOOC platforms.
The Development and Innovation of Archival Education in China under the Social Media Environment: Taking Archival WeChat Public Accounts Operated by Universities as an Example
Authors: Chen Yang , Zhan Yike
Published: September 2023

This paper conducts a thorough review of the current state of archival education within Mainland China. Furthermore, it endeavors to explore the future developmental trends of archival education within social media environments. To accomplish this, we examine the operation of WeChat public accounts of archives within Chinese universities as a prime example. The paper highlights the transformative role of social media on the conventional approach to archival education. Social media has fostered advancement and originality in archival education, broadened the scope and depth of its significance, and has had an unparalleled impact on its ongoing development. Nevertheless, the utilization of social media also poses a myriad of predicaments. The paramount difficulty we confront today pertains to how we can effectively harness the benefits of archival WeChat public accounts on a sustained and enduring basis, while ensuring their persistent existence and growth.
Influence of Librarians' Attitudes on Users' Patronage in Private University Libraries in Lagos State, Nigeria
Authors: Michael Juliana P , Olayemi Olalekan Moses
Published: September 2023

The study investigated the influence of librarians' attitudes on users' patronage in private university libraries in Lagos State, Nigeria. Survey design was used for the study. The study population comprised 5,616 undergraduates in five selected private university libraries in Lagos State, Nigeria. The sample size of 365 was determined using Research Advisor’s Table. Multi-stage sampling technique was used to select the participants and questionnaire was used to collect data. The collected data was analyzed using frequency, percentages, mean, standard deviation, and simple linear regression analysis was used to test the hypothesis. The findings of the study revealed that three dimensions of librarians’ job attitude measured; interpersonal relationship (M=3.28), professionalism (M=3.16), and perception and image (M=2.97) were all highly rated by the respondents. The study further revealed that the librarians’ attitudes significantly influenced library patronage of undergraduates in private university libraries in Lagos State, Nigeria (R2= 0.034, β = 0.185, t(300) = 3.263, p < 0.05). The study concluded that librarians’ attitudes had a significant influence on library patronage in private university libraries in Lagos State. Based on the outcome of the study, it is recommended that the librarians should increase their self-confidence by being proactive and strive to be in the forefront of university activities in order to gain more visibility and launder the image of their profession.
Are You Local? Academic Library Hiring Prior to and During COVID-19 in the United States
Authors: Quinn Andrea
Published: September 2023

Using only limited information, job candidates must assess academic libraries as prospective workplaces, while search committee members at academic libraries must make hiring decisions. Highlighting challenges that the pandemic posed to job seekers and search committee members, such as further limiting opportunities to gather information, this study compares a group of individuals hired by U.S. academic libraries before COVID-19 to a group of individuals hired by academic libraries during COVID-19. Results have implications for job seekers and hiring institutions, as they indicate that academic libraries hire more individuals with pre-existing ties to the state or region of the hiring institution and that the pandemic strengthened this tendency.
Librarians’ Attitudes, Needs, and Barriers to Participating in International Conferences: A Survey of ALA Members
Authors: Liu Grace , Frank Shoshana , Dawson Elizabeth , Olaniyi Olanike
Published: September 2023

This article presents the results of a survey of American Library Association (ALA) members exploring the interests, barriers, reasons, decision-influencing factors, support needs, and preferences of librarians in attending international conferences. The study reveals that although a majority of librarians expressed a strong interest in attending such conferences, more than half of them never or rarely participate, primarily due to a lack of institutional funding, which is more prevalent in public libraries. The primary reason for attending international conferences is to gain exposure to new perspectives and library practices in other countries. Factors such as the overall cost of the conference, its theme and reputation, and the availability of financial support also significantly influence librarians' participation decisions. To enhance and improve librarians' participation in international conferences, we recommend that professional institutions provide funding, advocacy, and informational support to help build their capabilities, networks, and awareness. Overall, the study highlights the significant potential for librarians to broaden their horizons and expand their professional development opportunities through attending international conferences and underscores the need for greater support and resources to facilitate their participation.
Perception of danger, coping strategies, and mental health in university population
Authors: Altamirano Nicol , Melo-Moreno Pablo , García Felipe
Published: September 2023

Objective: This study aimed to relate life satisfaction and psychological distress to coping with the perception of criminal danger in university students. Method: Three scales were used: The Life Satisfaction Scale, the K-10 Psychological Distress Scale, and the Coping with Perceived Danger Scale. A total of 370 university students participated, of whom 65.4% were female, and 13.8% had experienced crime in the previous two years. Result: A positive and statistically significant relationship was found between coping with perceived danger, such as cautious avoidance (r=0.274, p ≤ 0.00), preventive coping (r=0.344, p ≤ 0.00), and extreme avoidance (r=0.207, p ≤0.00), with psychological distress. These relationships were even stronger for victims of crime. Women show higher levels of psychological distress and more cautious, avoidant and extreme coping strategies in the face of danger compared to men. Finally, a negative and significant relationship was observed between psychological distress and life satisfaction. Conclusion: It appears that regardless of whether a person has been a victim of crime in the last two years, perceptions of danger and strategies of cautious and even extreme crime prevention are related.
Trichuris dolichotis Morini, Boero & Rodriguez, 1955 (Nematoda: Trichuridae) en Dolichotis patagonum (Zimmermann, 1780) (Rodentia: Caviidae) del centro para la conservación de fauna silvestre, San Juan, Argentina
Authors: González-Rivas Cynthia J. , Castillo Gabriel N. , Simoncelli Ivan
Published: September 2023

En Argentina existe un registro del nemátodo Trichuris dolichotis Morini, Boero y Rodriguez, 1955 (Nematoda: Trichuridae) parasitando la mara Dolichotis patagonum (Zimmermann, 1780), la cual corresponde a su descripción original del año 1955. En junio del 2023, en el Centro de Rehabilitación de Fauna Silvestre, provincia de San Juan, un ejemplar de mara macho D. patagonum murió por causas que se investigan. Se procedió a realizar la necropsia correspondiente, identificando durante el proceso a nemátodos hembras (n= 5) de T. dolichotis en intestino. Nosotros en el presente estudio presentamos un segundo registro luego de 58 años de no reportar su presencia, siendo el primer registro para la provincia de San Juan y el segundo para Argentina. El presente trabajo contribuye al conocimiento de la fauna de parásitos de mamíferos de Argentina.
Brand positioning strategies and their effectiveness: A case of high street fashion retail brands in Pakistan
Authors:   Faculty of Business Administration , Lahore School of Economics, Lahore, Pakistan, Shahid Saad
Published: September 2023

Brand positioning has been acknowledged by practitioners and academics to be an important element of brand management. Firstly, this study aims to investigate the relationship between three brand positioning strategies (benefit brand positioning strategy, feature brand positioning strategy and surrogate brand positioning strategy) and joint effect of the five dimensions of brand positioning effectiveness, namely, favourability, dissimilarity, uniqueness, credibility, and sustainability. Secondly, this study investigates the separate relationship between the three brand positioning strategies and the five dimensions of brand positioning effectiveness in the case of high street fashion apparel retail brands. To empirically test the proposed framework adapted measurement scales were used. Data from 607 young consumers in Pakistan were collected. Empirical findings confirm that benefit brand positioning strategy and surrogate brand positioning strategy have a greater effect on brand positioning effectiveness. However, a significant positive relationship was found between all three brand positioning strategies and brand positioning effectiveness. These findings also indicate varied yet insightful relationships between brand positioning strategies and five dimensions of brand positioning effectiveness. Marketers can benefit from these findings as a means to understand brand positioning strategies from a consumers’ perspective thereby making use of these results in articulating branding strategies as a way to generate and communicate a distinctive competitive perception for their brands.
Bacterial isolates and their antimicrobial susceptibility profile of superficial and deep-seated skin and soft tissue infections
Authors: Abid Khan Rao Muhammad , Dodani Sunil Kumar , Nadeem Ali , Jamil Sana , Zafar Mirza Naqi
Published: September 2023

Background

Skin and soft tissue infections (SSTIs) are caused by microbial invasion of healthy or damaged skin. SSTIs are difficult to manage and contribute to chronicity and emergence of antimicrobial resistance.

Objectives

To ascertain the prevalence of bacteria causing SSTIs and their antimicrobial susceptibility patterns.

Methods

A prospective study between November 2020 and May 2021. A total of 447 samples from SSTIs were analyzed.

Results

A total of 347 samples revealed mono-bacterial growth, of which 67% were male. SSTIs are common among patients aged 21–50 years with the dominance (78%) of gram-negative rods (GNRs). Escherichia coli (36%), Klebsiella spp. (22%), Staphylococcus aureus (16%), and Pseudomonas aeruginosa (11%) were predominant organisms. GNRs were highly resistant (>65%) to ciprofloxacin and trimethoprim–sulfamethoxazole. For injectable antibiotics, the highest resistance was determined against ceftriaxone, and the least resistance was determined against amikacin. Resistance against carbapenem was the highest among P. aeruginosa (53%) and Klebsiella spp. (32%). S. aureus showed the highest resistance against ciprofloxacin, and the least resistance was determined against clindamycin. Of 57 S. aureus isolates, 86% isolates were methicillin-resistant Staphylococcus aureus (MRSA). All isolates of P. aeruginosa and S. aureus were sensitive to polymyxin B and vancomycin, respectively. The prevalence of multidrug-resistant E. coli and Klebsiella spp. was higher among deep-seated SSTIs (dSSTIs).

Conclusions

The predominant etiology of SSTIs is GNR. Currently, there is very high resistance against oral antibiotics. Antimicrobial resistance against carbapenem has also increased. Moreover, there is a high frequency of MRSA. MDR E. coli and Klebsiella spp. isolates are frequently involved in dSSTIs.
Copy number variations of cytochrome P450 genes in Kinh Vietnamese
Authors: Vu Nhung Phuong , Nguyen Ton Dang , Nguyen Binh Huy , Nguyen Duong Thuy , Nong Hai Van , Nguyen Ha Hai
Published: September 2023

Background

The cytochrome P450 (CYP450) family is well known as a major group of drug metabolizing enzymes. The polymorphism of CYP450 genes is the main factor having an impact on the interindividual difference in drug response, including drug efficacy and drug safety. The single nucleotide polymorphism (SNPs) of Vietnamese Kinh has been widely studied, but information about the copy number variations (CNVs) of other CYP450 genes is still unknown.

Objective

To identify the CNV variability of CYP450 in 154 healthy unrelated Kinh Vietnamese, except eCYP2D6, which was previously reported.

Methods

Multiplex Ligation-Dependent Probe Amplification (MLPA) was applied for determination of copy number of 10 CYP450 genes. Later, PCR or quantitative PCR (qPCR) was used to confirm the detected CNVs in randomly chosen subjects.

Results

Of the 154 subjects, along with CYP2D6, 4 other CYP450 genes showed CNVs including duplications (CYP1B1), deletions (CYP2A6 and CYP2C9), and both duplications and deletions (CYP2E1). Among these, CYP2A6 exhibited the greatest frequency of CNVs compared with other CYP450, in which CYP2A6Del accounted for 11%. Meanwhile, allele CYP2E1Del showed the lowest frequency with only 0.3%.

Conclusions

The present study provides new insight into CYP450 CNVs in the Kinh Vietnamese cohort. Our data have contributed to genetic profiling of CYP450 CNVs in Vietnam, which would be helpful for facilitating implementation of pharmacogenetics in drug dosing adjustment in Vietnam.
The use of traditional Chinese elements in modern interior design in the context of multimedia
Authors: Zhu Zhenji
Published: September 2023

Chinese traditional elements have to carry on their own inheritance and innovation in continuous social development, and this process will encounter different challenges and complex problems. In order to better integrate traditional elements into interior design, this paper analyzes the current situation of integrating traditional elements into modern interior design, uses a neural network model to explore the influence of multimedia context on the modern interior design of traditional Chinese elements, and investigates modern people’s preference for the way traditional elements are integrated into modern interior design through a questionnaire survey. The results show that the priority factors for choosing an interior design, the number of consumers aged 20-35 who prefer their favorite style in home decoration, accounts for about 40% of the total, and the cross analysis shows that the sense of atmosphere accounts for 15%, which shows that young people around 20-35 years old have the personality of the times and pursue a high quality of life. Only the age older users will consider comfort. It can be seen that interior design with traditional elements is more in line with the preferences of older people. Inheritance and innovation of traditional Chinese culture is a huge challenge, and the reasonable integration of traditional and modern science needs to make attempted more.
Analysis of the impact of college students’ innovation and entrepreneurship on human resource index of science and technology enterprises based on logistic regression model
Authors: Wang Jia , Li Li
Published: September 2023

Considering the immediate phenomenon of uncoordinated advancement, unbalanced distribution and unreasonable structure of regional human resources and academy undergraduates’ innovation and start an undertaking ability in China, this paper fundamentally constructs academy undergraduates’ innovation and entrepreneurship system through a logistic regression model. The study takes 29 provinces and regions in China as research samples and adopts the logistic regression model BP neural network method to conduct a more in-depth theoretical discussion and empirical analysis on the interaction mechanism and the coupled and coordinated development of regional manpower capital and produce and start an undertaking ability in China. The coupling and coordination degree of manpower capital and production and start an undertaking in 29 provinces and regions in China is lower than 0.8, and the average value is 0.358, which is in the “mild dysfunctional decline” stage. There are some mutual constraints between the subsystems of human resources of science and technology enterprises and the products and start an undertaking ability of academy undergraduates, and more efforts must be made in their respective “shortcomings” and comparative disadvantages to promote the synergy and consistency of their development levels. We should strive to strengthen cooperation with foreign countries and introduce advanced technology and outstanding talents from developed countries. In the “import” at the same time “go out”, in the learning from the same time also “teach others to fish”, in order to achieve win-win cooperation.
Noise Reduction of Cable Partial Discharge Vibration Signal based on EEMD-CIIT method
Authors: Tan Xiao , Zhang Wei , Chen Jie , Li Chenying , Cao Jingying
Published: September 2023

The cable partial discharge vibration signal is often polluted by noise. It is necessary to denoise the signal, improve the signal-to-noise ratio, and then realize the feature extraction of the vibration signal. Therefore, this paper builds a cable partial discharge test platform, collects the time-domain waveform of vibration signals under different working conditions, analyzes the noise reduction effect of ensemble empirical mode decomposition clearing repetition interval threshold noise reduction method under different threshold functions, and analyzes the difference and approximation degree between the simulated signal and the real signal after noise reduction by using signal-to-noise ratio and correlation, By comparing the difference of statistical characteristics in different defects before and after noise reduction, the wavelet threshold denoising method is established synchronously and compared with the proposed method. The results show that the high-frequency part of the vibration signal has obvious random noise components, and the effective frequency is mainly concentrated in the low-frequency band; The smoothing shear absolute deviation penalty threshold function has the smoothest curve after noise reduction and the highest approximation to the real signal. The high-frequency noise component is eliminated, and the low-frequency band frequency component is effectively retained. The method proposed in this paper can be extended to the noise reduction of vibration signals of other industrial equipment and provide technical support for the signal noise reduction of various industrial equipment.