bluuebunny/crossref_metadata_2025 huggingface dataset:
Introduction
Authors: Williams Deanne
Published: December 2024

In a short introductory essay, Deanne Williams discusses the emerging field of Girls Studies and the recent publication of books on girls in Shakespeare and the Renaissance. She argues that the process of Shakespeare adaptation often includes and incorporates girlhood, and proposes that girlhood and adaptation share much in common through a traditional perception that dismisses them as secondary and derivative. She also guides readers through this special issue on Girls and Girlhood in Adaptations of Shakespeare, highlighting how each contribution represents girlhood.
Actresses, Artists, Authors: Women Shakespeareans in the Nineteenth Century
Authors: Desmet Christy
Published: December 2024

This Introduction analyzes the rise of twentieth-century Shakespeare as a reaction against not only Romantic versions of Shakespeare, the usual target of academic analysis after T. S. Eliot, but also feminine, and often feminist, approaches to Shakespeare produced by women actors, artists, and authors in the nineteenth century. These women, in turn, engage not just with the nationalist figure of King Shakespeare, as epitomized by Thomas Carlyle's On Heroes, Hero-Worship, and the Heroic in History, but also with one another in networks that are sometimes personal, sometimes dispersed.
The Fiendlike Queen: Recuperating Lady Macbeth in Contemporary Adaptations of Macbeth
Authors: Carroll William C.
Published: December 2024

Many adaptations and appropriations in recent decades have attempted to recast the "fiend-like queen" Lady Macbeth in a more positive light — a difficult task, given her actions in Shakespeare's play. These representations move far away from earlier texts in which "Lady Macbeth" is little more than a synonym for a murderous woman. Several recent works of popular culture seek, instead, an explanation or rationale for her participation in Duncan's murder through reference to her earlier marriage and son by that marriage (both suppressed in Shakespeare's play), to her situation as a woman in a culture of Celtic masculinity, and even to a supposed daughter, with whom she is ultimately reunited. The result is a repentant, heroic, even justified Lady Macbeth. Among the works discussed are Gordon Bottomley, Gruach(1919), Susan Fraser King, Lady Macbeth: A Novel (2008), Lisa M. Klein, Lady Macbeth's Daughter (2009), and A. J. Hartley and David Hewson, Macbeth: A Novel (2012).
The Utah Shakespeare Festival / Southern Utah University Annual Shakespeare Competition Authors
Authors: Bahr Michael , Weingust Don
Published: December 2024

The Utah Shakespeare Festival / Southern Utah University Shakespeare Competition brings upwards of 3,000 students from over 100 high schools and middle schools to Cedar City, Utah each fall to compete in one of the longest-running programs of its kind in the nation. The Competition, mixing elements of competitive and non-competitive gatherings, provides a centerpiece for early academic-year educational programming in Shakespearean literature, theater, dance, and music. The Competition provides significant opportunity for "service Shakespeare," not only for competing students, but also for the sponsoring Shakespeare Festival and University and for many of the University's students, while raising and addressing questions in the controversy over competitive versus non-competitive educational programming. The Competition has developed within a cultural milieu that has contributed significantly to its success.
Joanna Baillie and the Anxiety of Shakespeare's Influence
Authors: Slagle Judith Bailey
Published: December 2024

Joanna Baillie, a drama critic as well as a dramatist, began during the last decade of the eighteenth century to develop her own theory of tragedy and comedy, based on human emotions, the elemental instincts that prompted Shakespeare's characters to action over two hundred years before. Baillie could not escape Shakespeare's early influence; even if she had tried, critics and colleagues regularly reminded her of her debt. While Baillie admitted her poetical debt to Ossian and to Robert Burns, her Romantic "naturalness" was indeed fresh and original. Her dramatic writing, however, followed many of the themes of Shakespeare — love, hate, revenge, jealousy, ambition — and she defended and defined her focus on such passions in her "Introductory Discourse" to A Series of Plays, whereas Shakespeare was tacit about his scheme if, in fact, he had one.
"'Late' has no meaning here": Imagining a Second Chance in Toni Morrison's Desdemona Authors
Authors: Erickson Peter
Published: December 2024

Toni Morrison's Desdemona dramatically displaces Othello as the title character in Shakespeare's play. Morrison's renaming signals her re-vision of Othello by giving Desdemona an afterlife that restores her voice and activates her pursuit of further development beyond Shakespearean limits and without Othello. What enables this change is Desdemona's exploration of newly established and newly emphasized bonds with female characters, notably Emilia and Barbary.
Macbeth Behind Bars
Authors: Ko Yu Jin
Published: December 2024

Macbeth has a long history as the kind of morality fable that has served the age-old Horatian objectives for literature of pleasure and instruction. However, the play also has a stage history of inviting terrifying but highly sympathetic portraits of Macbeth, especially as actors (and the culture at large) became more and more interested in studying inner psychology. The interpretive tradition has sometimes found the tension between straight moral instruction and sympathy for evil difficult to reconcile. This difficulty clearly gets ratcheted up in unpredictable ways when actual inmates who are in prison for violent crimes, including murder, perform the play in prison. My critical review works through some of the issues that surfaced during a Shakespeare Behind Bars production of Macbeth at the Luther Luckett Correctional Institution in La Grange, Kentucky.
The Cult of Shakespeare in Soviet Russia and the Vilified Ophelia
Authors: Khomenko Natalia
Published: December 2024

This article examines the representations of Ophelia in Soviet academic and literary texts, as well as in Grigori Kozintsev's internationally renowned film version of Hamlet. Analyzing the Soviet cult of Shakespeare, I argue that Soviet portrayals of Ophelia — ranging from a threatening mechanical creature to a shrinking doll — reflect the difficulty of legitimizing Shakespeare and his plays, even under conditions of strict ideological control. Accepting Shakespeare as a proto-socialist writer, and lauding Hamlet as a people's hero, requires a struggle against the text and a policy of determined misreading. As a disruptive girl character, not easily assimilated into the centralizing force of communist ideology, Ophelia is marginal to the masculine project of state-building into which Shakespeare, and consequently Hamlet, are co-opted. In Soviet portrayals, she embodies the doubt about how Shakespeare's foreign birth and bourgeois origins might affect his potential for properly educating proletarian readers. This representational trend continues beyond the fall of the Soviet Union in 1991; at the same time, post-Soviet women authors query Ophelia's marginal status, using her as a point of entry into the cultural canon.
"What service is here?" Exploring Service Shakespeare
Authors: Jensen Michael P.
Published: December 2024

This introduction to the cluster on Service Shakespeare introduces the essays, considers the current state of the field, and suggests topics for future consideration.
The Bard's Speech: Making it Better; Shakespeare and Therapy in Film
Authors: Ridden Geoffrey M.
Published: December 2024

This paper will argue that Shakespeare has become so prevalent and powerful in popular entertainment as a shorthand to signal high culture that his name and his works can be invoked as therapeutic even in circumstances in which, historically, they did not feature. I will first seek to chart the place and power of the process of Shakespearization. I will then examine the prevalence in popular film of figures with disabilities. Finally, I will consider the particular fictional role that Shakespeare can play as a form of therapy for some of these historical protagonists with disabilities, a role that Shakespeare did not fill in their real lives.
Shakespeare, King of What? Gender, Nineteenth-Century Patriotism, and the Case of Poet-lore
Authors: Lootens Tricia
Published: December 2024

This essay contextualizes Thomas Carlyle's "King Shakespeare" in the context of women's nineteenth-century patriotism and the journal Poet-lore, which was co-founded by Charlotte Porter, the editor of Shakespeariana. Lootens uncovers the ways in which a "cosmopolitan, feminist" Shakespeare emerges in the nineteenth century through female editorships and women's reading circles, often in opposition to the imperialistic, English Shakespeare championed by Carlyle. American women's reading circles explicitly connected female education with active citizenship, idealizing the Shakespearean heroine as a "New Woman" as they did so. Poet-Lore's 1896 section on new readings of The Taming of the Shrew is exemplary in this regard, attempting to recuperate Katharina's final speech as an expression of ethical and personal reform. The essay concludes by observing that although Poet-Lore's racial politics can oppose white American civic womanhood to "foreign, ignorant voters controlled by demagogues," it nonetheless engages Porter's own assertion that a cosmopolitan or multicultural influence was not only desirable but also necessary for the full development of American civilization.
"Making the Stage my Profession": Girlhood and Performance in Mary "Perdita" Robinson's Memoirs
Authors: Bicks Caroline
Published: December 2024

Mary Darby Robinson (1758-1800) was one of the most famous actresses of her time. A notorious affair with the Prince of Wales, sparked when he saw her in David Garrick's adaptation of Shakespeare's The Winter's Tale, left her indelibly marked with the nickname "Perdita." While it may seem a stretch to connect the adulteress Mrs. Robinson to Shakespeare's sixteen-year-old virgin, Robinson did just that when she constructed her girlhood self in her posthumously published Memoirs. The similarities between Shakespeare's lost girl and Robinson's invented one suggest that she was using Perdita's tale to negotiate and produce her own story. Although Robinson was twenty-one, married, and a mother when she played Perdita in Garrick's adaptation, I contend that Robinson uses Shakespeare's young heroine to do two things: first, to produce herself as a sexual innocent attempting to preserve her "natural" girlhood against the demands of a culturally mandated sexual role; and second, to re-imagine the whore-making space of the theater as a stage of girlish freedom and refuge from the social and biological demands of womanhood.
"Playing the Men": Ellen Tree, Fanny Kemble, and Theatrical Constructions of Gender
Authors: Russell Anne
Published: December 2024

Ellen Tree, the first English performer to regularly play tragic male roles, initiated a nineteenth-century Anglo-American convention in which many women performers played a limited number of tragic male roles, primarily Romeo and Hamlet. Nineteenth-century women's performances of tragic male characters point to multiple tensions and fissures in the understanding and representation of gender in theater. Tree's negotiation of these tensions and her decisions about how, and in what contexts, to play tragic male roles indicate her awareness of the ways in which shifting social perspectives on gender might be accommodated in her stage representations. She followed her enthusiastic and romantic Romeo with Thomas Noon Talfourd's Ion, whose dignified and "classical" character offered a kind of idealized and unsexualized masculinity that was not too deceptively "realistic." Thirty years after she had first performed Romeo with Fanny Kemble as Juliet, Tree attended several of Kemble's public readings of Shakespeare, in which Kemble read all the roles. Tree expressed a combination of admiration and disquiet at the way Kemble "read the men best." Tree's mixed emotions about Kemble's reading register not only her recognition of changing social mores, but also unresolved tensions and ironies in Tree's own theatrical practices. Audience responses to Kemble's readings show astonishment at her intensity and emotionality, particularly her strikingly convincing readings of male characters. These strong audience reactions to Kemble's readings of Shakespeare's plays suggest that the expressions of emotionality possible in public reading could be perceived as more dangerously exciting than stylized and conventional stage performances of the period. Kemble had often criticized acting as overly emotional, and considered stage performance to be less respectable and less intellectual than reading plays aloud without costumes or stage action. Yet Tree, who had performed regularly onstage for over forty years, was shocked by the emotion and lack of restraint in Fanny Kemble's reading. The contradictions and ironies in responses to the stage performances and readings of Tree and Kemble indicate they were both judged for exceeding social expectations of womanly restraint, even as they felt, expressed, and responded to strong emotion in both reading and performance.
Is Wrestling a Promising Sport for Youngsters from Deprived Regions?
Authors: Taşkıran Celal , Kutlu Mehmet , Demirkan Erkan , Yıldırım Turgut
Published: December 2024

This study aimed at exploring the social factors in lead young wrestlers with disadvantaged background and from
deprived regions to take up wrestling. Utilizing a cross-sectional survey design, the research explores demographics, socioeconomic status, and the motivators behind wrestling involvement among 129 participants aged 9 to 16. Purposefully selecting
regions with limited wrestling activity, the study is part of a special project. Conducted incentive camping period in Antalya study
reveal that key motivators to wrestlers include Physical Education Teachers (PET) (22%), friends (19%), siblings (15%), fathers
(12%) and others (14%). Although, there were 70% of participants who have some idols from countrywide, it was found that they
have lack of idols in the regions of our participant group. Despite wrestlers have some disadvantages in social status such as
the lack of wrestling authority in family members, camping affected them positively and encouraged them in wrestling career.
Prospective wrestlers had declared that they come from low-income families underlining the socio-economic difficulties. It is
thought that situations such as conducting the study in a seaside camp in a 5-star hotel, recognizing idol athletes increase the
children’s interest in wrestling and will have a positive effect on their future sports life despite their disadvantaged backgrounds
Leukocyte populations detection in young athletes in resting phase based on scatter properties using a Flow Cytometric approach
Authors: Marko Ornela , Vrenjo Klotilda , Sulçe Majlind
Published: December 2024

Complete blood count analysis has a major importance as a first laboratory evaluation. In particular data obtained from complete blood count are relevant to correctly diagnose and follow up different medical conditions. In athletes, medical examinations and laboratory test are mandatory, especially when a sportive event will soon take place. Different automatic techniques are used to evaluate percentages of different leukocyte populations with a high accuracy. Flow cytometry represents a technology that is mainly used to diagnose different lymphoproliferative and myeloproliferative neoplastic disorders. In this study 127 samples from clinically healthy young athletes were collected and analyzed with both flow cytometry and automatic method to evaluate the usefulness of flow cytometry in detecting different leukocyte populations based on their scatter properties. Results showed that flow cytometry is a reliable technique having showed a high accuracy for different cell populations. Intra class correlation coefficient was >0.80 for all populations showing a high correlation between the two methods. However, a higher number of cases, the involvement of other automatic techniques are mandatory to confirm these results.
Ferritin Level Analysis to Identify Iron Deficiency in Qualified Athletes
Authors: Husarova Anna , Vdovenko Nataliia , Maidaniuk Olena , Rossokha Halyna
Published: December 2024

The world of elite sports is marked by intense physical and psychological strains, significantly augmenting the demands on athletes' bodies and rendering them susceptible to iron deficiency, and anemia, especially women athletes. Iron deficiency can have severe consequences, including heightened injury risks, delayed recovery following physical exertion, compromised immunity and diminished athletic performance. Notably, iron deficiency in athletes can persist without manifesting as anemia. Consequently, comprehensive research is crucial to identify iron deficiency states in athletes. Our study focused on researching the ferritin content and other indicators of iron metabolism in the blood of 159 qualified athletes (98 men and 61 women) who specialized in various sports. The research entailed the assessment of ferritin concentration, hemoglobin, iron content, red blood cell count, and hematocrit level. The findings revealed a considerable prevalence of hidden iron deficiency among female athletes, with 54% exhibiting prelatent iron deficiency and 16% presenting with latent iron deficiency. They require appropriate recommendations for treatment and prevention. The results of our research confirm the presence of the iron deficiency problem in athletes, especially women. Due to the above, identifying not only iron-deficiency anemia but also hidden iron deficiencies is crucial to ensure timely and effective treatment and prevention.
A Security Community or a Game of Interests? Opportunities and Threats in Central Europe During a Time of Crisis
Authors: Gizicki Wojciech
Published: December 2024

The war in Ukraine and the multidimensional crisis in Europe are adversely affecting the position, ability, and possibilities of cooperation in Central Europe. For the past 30 years, the Central European nations, despite their natural differences, have been able to engage in lasting cooperation to ensure their own and the region’s security. It seems that there has been a unique kind of cooperation for common interests, as Karl Deutsch puts it. Presently, we can see that, due to the decisions of voters, diverse interests, and the external position of the Central European nations, there are internal differences and divisions. In some cases, the region’s nations have a specific kind of personal game of interests. The article will attempt to outline the latest and most relevant matters that are high on the region’s agenda, particularly taking into account opportunities and threats.
Clinical features of hypertension in patients with normal weight and overweight
Authors: Bulda V.I. , Berdnyk I.O. , Barabanchyk O.V. , Rodionova I.O.
Published: December 2024

Objective of the study: То determine the clinical features of arterial hypertension in overweight patients.
Materials and methods. There were 170 patients included in the study and depending on body weight were divided into two groups: group I – 86 patients with normal body weight and group II – 84 patients with overweight. In our work we calculated the proportion of patients with abdominal obesity and also analyzed concomitant pathology according to the available medical documentation and anamnesis.
Results. There were slightly more women in the two groups. Comparing the data of office measurement of systolic and diastolic blood pressure in patients with hypertension with normal weight and overweight didn’t show significant differences. The most significant association was observed between patients with overweight and nonalcoholic fatty liver disease (objective data (OD) 3.25; 95% confidence interval (CI) 1.55–5.13) and with impaired glucose tolerance (OR 3.54; 95% CI 1.12–5.68). The percentage of patients with dyscholesterolemia was also statistically higher, although slightly lower than in previous cases (OD 2.61; 95% CI 1.05–3.87) and with gastroesophageal reflux disease (OD 3.14; 95% CI 1.56–5.99). A direct correlation was found between patients with abdominal obesity and the presence of gastroesophageal reflux disease (r = 0.56, p < 0.01), dyscholesterolemia (r = 0.53, p < 0.05) and with diabetes (r = 0.45, p < 0.05). In addition, patients who smoked significantly more often had coronary heart disease (p = 0.044).
Conclusions. The article summarizes information on the clinical features of arterial hypertension in overweight patients. The prevalence of hypertension among the adult population is 30-45%, with overweight and obesity continuing to occupy leading positions among young and mature people in the developed world and in middle-income countries. Determining the features of the course, duration of the disease, the distribution between stage and degree in this category of patients will help to develop optimal algorithms for patient management.
Uterine fibroid in the premenopause: experience of medication treatment
Authors: Kravchenko О.V.
Published: December 2024

Objectives of the study: to evaluate the effectiveness of the progestogens for the treatment of uterine fibroids (UF) in women in the premenopausal period.Materials and methods. 42 patients aged 45–50 years with UF were examined. The diagnosis of UF was verified according to clinical and instrumental research methods. The effectiveness of the therapy was evaluated according to clinical and ultrasound examination data before and during the course of treatment. All patients with diagnosed symptomatic UF received progestogen dienogest 2 mg ones a day continuously for a year, with clinical and sonographic control every 3 months.Results. UF was symptomatic in all examined patients. According to the International Federation of Gynecology and Obstetrics (FIGO) classification system for UF, 42.8% (18) of women had type III–IV nodes, 54.8% (23) had type II–V nodes, and 2.4% (1) of women had type VI nodes. In all patients were 2 or more nodes.Already after 6 months of therapy, bleeding complaints decreased by more than 8 times, moderate pain syndrome and urination disorders were noted in only one (2.4%) patient. After 12 months, pelvic pain and bladder dysfunction were absent in 100% of cases. One (2.4%) patient had spotting bleeding for 2 days during the 8th month of treatment. After 6 and 12 months of treatment, the size of the endometrium decreased significantly to 3.6–7 and 3.2–4.6 mm, respectively. The total volume of the uterus also underwent positive changes: it decreased by 10–40% in each patient during the course of treatment.Conclusions. It should be preferred progestogens in the treatment of UF in women aged 45–50 years who wish to preserve the uterus. Therapy with dienogest in a continuous long-term regimen showed high clinical effectiveness, confirmed the active antiproliferative, antiovulatory effect of the drug in the absence of estrogen deficiency symptoms, which is important for this  age group of patients.
The effect of vitamin D and magnesium deficiency on the course of adenomyosis in the post covid-19 period in women of reproductive age
Authors: Zaporozhchenko M.B. , Bulhar A.V. , Stepanov G.F.
Published: December 2024

Objective of the study: to investigate the content of vitamin D and the trace element magnesium in the blood of women of reproductive age with adenomyosis of the I–II and III–IV degrees after the COVID-19 disease depending on the algorithm of their management at 3, 6 and 12 months, as well as assess the general condition of patients.Materials and methods. 150 women after the COVID-19 disease were under observation: 30 practically healthy women (control group A), 60 patients with adenomyosis of the I–II degree (group B) and 60 patients with adenomyosis of the III–IV degree (group C). Observation continued for 3, 6 and 12 months after the COVID-19 disease.Results. Deterioration of well-being in patients with adenomyosis in the first months after COVID-19 has been proven. The frequency of complaints increased significantly: lethargy (55.0%), headache (36.7%), joint pain (41.7%), muscle pain (40.8%), pelvic pain (38.3%), dyspareunia (100%), etc. According to the scale of verbal assessment of pelvic pain, moderate pain (2 points) was experienced by 30.0% of patients of group B and 43.3% in group C, at the same time, severe (3 points) – 33.3%, very strong (4 points) – 20.0%.A significant decrease in the level of vitamin D and Mg was detected in women after the COVID-19 disease (p < 0.05): in almost all healthy women (group A) and in patients with adenomyosis (groups B and C). A significantly lower content of vitamin D and Mg was found in groups B and C compared to group A (p < 0.05), and in group C compared to group B.The effectiveness of taking vitamin D and magnesium preparations in patients with adenomyosis after the COVID-19 disease was confirmed: a significant difference in the frequency of symptoms characterizing the general condition of patients after 3, 6 and 12 months was obtained: a decrease in the frequency of neuroses, headaches, muscle pain, constant lower abdominal pain, dyspareunia, etc.Conclusions. The effectiveness of taking vitamin D and magnesium preparations by women with adenomyosis after the COVID-19 disease has been confirmed.
Morphofunctional features of isthmocele complicated by abnormal uterine bleeding
Authors: Hladchuk Z.I. , Rozhkovska N.M. , Sytnikova V.O. , Syvyi S.M.
Published: December 2024

Background. The frequency of cesarean section remains high, and in some countries it exceeds 40% of all deliveries. The prevalence of isthmoceles as a consequence of cesarean section according to different authors ranges from 19 to 84%. Symptomatic isthmoceles is most often accompanied by abnormal uterine bleeding in 30-55% of women. Objective of the study: to determine the functional, morphological and immunohistochemical features of isthmocele complicated by abnormal uterine bleeding. Materials and methods. A prospective study was conducted, 68 patients were under observation: 38 patients of reproductive age with isthmocele after cesarean section who sought medical care for abnormal uterine bleeding (group 1, the main) and 30 practically healthy women of the same age with a normal uterine scar (group 2, the control). Immunohistochemical examination was performed in paraffin sections. Primary and secondary antibodies were used to detect CD34, CD68 and CD138 markers. Results. Patients with isthmocele complicated by abnormal uterine bleeding have an increased body mass index, a higher frequency of dysmenorrhea, excessive menstruation, heavy menstrual bleeding, intermenstrual bleeding, anemia, compared with women with a complete uterine scar (p < 0.01). Isthmoceles in 84.2% of cases was associated with ultrasonographic and pathologic signs of adenomyosis, with insufficiently effective treatment of abnormal uterine bleeding noted in 78.9% of cases, and no effect of conservative treatment in 21.1% of cases. The high expression of CD34, CD68, CD138 markers in the areas of the isthmoceles complicated by abnormal uterine bleeding indicates the activity of adenomyosis and the presence of chronic endometritis, which determines the specificity of the clinical picture and requires improvement of treatment approaches.Conclusions. Accounting the functional, morphological and immunohistochemical features of isthmocoele complicated by abnormal uterine bleeding will improve the effectiveness of treatment of symptomatic isthmocoele.
Effect of Fruit Load on Seed Quality of Cowpea Varieties [Vigna unguiculata (L.) Walp. (Fabaceae)]
Authors: Komenan Any Olivier , Kouakou Adjoua Dorcas , Koffi Niambet Jean-Michel , Diawara Mamadou Israël , Koffi Kouamé Kévin
Published: December 2024

Background: The development of cowpea cultivation needs to be given priority because, in developing countries, cowpeas make up for many protein deficiencies. Producing quality seeds of this legume would be an essential objective if food security is to be achieved. This study aimed to establish the appropriate fruit load for optimum production of quality cowpea seed. Methods: To achieve this, the impact of five different fruit loads (10, 20, 30, 40 and 50 pods per plant) on the yield of four cowpea varieties (KVx745-11P (V1), KVx775-33-2G (Tiligré) (V2), Gourgou (V3) and KVx780-6 (V4)) was assessed. The seeds’ germination capacity and the seedlings’ vigor were then assessed for each of the four varieties. Result: Findings showed that seed length, width, thickness and weight changed significantly with increasing load in all varieties. The shortest time to emergence was recorded in the V1 variety for seeds from fruit loads of 20, 30, 40 and 50 pods per plant. For the ten pods per plant fruit load, the shortest emergence time was achieved with the V4 variety. The varieties V1, V2 and V4 studied produced excellent agronomic quality seeds when the pod was harvested with a load of 10 pods per plant. The fruit load significantly affected the seed quality and yield across all four varieties. Seeds from the minor C10 load for varieties V1, V2 and V4 and C20 for variety V3 exhibit high seedling vigour.
Exploring Sustainable Tourism through Semio-Linguistic Analysis: The Case of Europe's Top Destinations
Authors: Mocini Renzo
Published: December 2024

The ubiquitous presence of the term “sustainability” in the “semiosphere” explains why it has acquired multiple meanings in common usage, depending on the domain of discourse within which it happens to occur. The present contribution seeks to explore the semantics of sustainability within the specific discourse domain of tourism, where it is largely addressed and exploited for promotional purposes. Considering the key role played by sustainability as a determining factor in the choice of a tourist destination, many countries’ institutional tourist websites include a section dealing with sustainable travel. Drawing on quantitative and qualitative analysis, this study investigates the semio-linguistic mechanisms by means of which a locality aims to build up an image of itself as a sustainable destination. The examples discussed are taken from a corpus of promotional institutional webpages and selected to best represent how the promotors of destinations entrust discourse with the task of creating meanings capable of influencing tourists’ perceptions and choices. The semio-linguistic analysis will reveal the presence of a series of narrative constants and valorisation strategies beneath the apparent diversity of the discursive surface of the promotional webpages investigated. It will also help outline the profile of the potential “sustainable” tourist inscribed in the texts under consideration.
Management of a Corneal Perforation Due to Resistant Peripheral Ulcerative Keratitis by Repeated Tectonic Patch Grafting Combined with Conjunctival Resection
Authors: Bulut Okyanus , Kaşıkcı Murat , Eğrilmez Sait , Barut Selver Özlem
Published: December 2024

Tectonic graft patching and conjunctival resection is one of the effective treatment modalities in especially resistant PUK patients with corneal perforation additional to topical and systemic immunosuppressive treatment. A 44-year-old female patient with a 10-year history of rheumatoid arthritis, was referred to our clinic with peripheric corneal perforation. Her visual acuity was at the level of hand movement perception in the left eye. Slit-lamp examination revealed medial PUK with corneal perforation. Tectonic patch grafting was performed. Two weeks later, because of small melting area at the inferior part of the graft with iris incarceration, an additional cornea-scleral graft transplantation was performed. Due to the immune nature of the PUK, limbal conjunctiva at the perforation site was also resected. Three months after the re-grafting, there was no recurrence. Best corrected visual acuity was 5/10 log MAR in the left eye.
Evaluation of lipid profile and statin therapy in patients with atrial fibrillation: Real-life data from a tertiary hospital
Authors: Naser Abdulrahman , Uzun Yucel , Sayılan Samet , Güven Oya , Demireller Merve , Ekmekci Ahmet
Published: December 2024

Aim: Dyslipidemia is a modifiable risk factor of atrial fibrillation (AF). However, the majority of patients either do not receive low-density lipoprotein cholesterol (LDL-C) lowering treatment or do not meet their LDL-C and non-high-density lipoprotein cholesterol (non-HDL-C) goal. We aimed to search whether patients with AF are being treated for dyslipidemia and/or are at target LDL-C and non-HDL-C levels if treated.
Materials and Methods: This cross-sectional analysis includes 725 AF patients and was performed between 20 May 2023 and 25 November 2023, in cardiology outpatient clinics of a tertiary hospital. The demographic and clinical features of the patients were recorded. Systemic coronary risk estimation-2 (SCORE2) and old person version algorithms were used for cardiovascular disease (CVD) risk estimation. Primary prevention (PP) group involved patients with low-to-moderate, high and very high CVD risk without established atherosclerotic cardiovascular disease (ASCVD) and secondary prevention (SP) group was consisted of patients with established ASCVD.
Results: The mean age of the participants was 71.98± 9.01 and 54.5% (n=368) of patients were females. 207 (30.7%) of patients were paroxysmal AF, and 468 (69.3%) were permanent AF. Prevalence of dyslipidemia and hypertriglyceridemia were 364 (53.9%) and 248 (36.7%) respectively. 9 (1.3%) and 152 (22.5%) of patients were on fibrate and statin treatment respectively. Mean LDL-C and non-HDL-C were 107.81±35.97 and 135.42±41.19 and their target attainment rates were 62 (9.2%) and 107 (15.9%), respectively.
Conclusion: Control of dyslipidemia in patients with atrial fibrillation was severely poor and the most common cause was physician negligence.
The application of BLUE (Bedside Lung Ultrasound in Emergency) protocol in the emergency department
Authors: Ersan Eylem , Kıyan Güçlü , Ersel Murat , Karbek Akarca Funda , Bayraktaroğlu Selen , Boydak Bahar
Published: December 2024

Introduction: This study aimed to evaluate the effectiveness of lung ultrasonography (US) in detecting the cause of acute respiratory distress in the emergency department.
Methods: This cross-sectional analytical study was carried out on 195 adult patients who were admitted to the Emergency Department of a University Hospital with acute respiratory failure in 6months period. The validity of the US diagnoses was assessed by comparing the decisions made by researchers according to the BLUE protocol classification with the final judgments made by the primary doctors using gold-standard diagnostic techniques suggested by the guidelines.
Results: The diagnostic accuracy of lung US was 89.7%. While Congestive Heart Failure (CHF) (n=91), Chronic Obstructive Pulmonary Disease (COPD) (n=53), pneumonia (n=69), and Pneumothorax (PTX) (n=5) could be diagnosed by ultrasound with high sensitivity and specificity, its specificity in the diagnosis of Pulmonary Thromboembolism (PTE)(n=18) was low (67%). Ultrasonography could also diagnose combined pathologies such as pneumonia associated with CHF, or pneumonia associated with COPD, with high sensitivity and specificity. It has been determined that the diagnostic accuracy of the routine physical examination and lung radiography used in the emergency room to assess bedside respiratory distress is lower than that of ultrasonography.
Discussion: In this study, we found that lung US was effective in the diagnosis of CHF, COPD, pneumonia, PTE, and PTX. Compared to the gold standard tests, it shortened the duration of the diagnosis. Finally, US can also be applied safely in centers where advanced diagnostic facilities are not available.
Impact of KLF4, SHH, and hif1a knockdown on miRNA expression in malign melanoma cancer stem cells
Authors: Ozdil Berrin , Biray Avcı Çığır , Aktuğ Hüseyin
Published: December 2024

Aim: microRNAs (miRNAs) play a pivotal role in gene regulation, influencing various cellular processes such as differentiation, proliferation, and apoptosis. This study investigated the expression of three specific miRNAs (Hsa-miR-21-5p, Hsa-miR-9-5p, and Hsa-miR-200a-5p) in malign melanoma stem cells (CSCs) and non-stem cells (NSCs).
Method: CSCs and NCSCs were sorted from CHL-1 cells based on CD133 marker, a malignant melanoma cell line. CD133+ cells were treated with Hif1a, KLF4, and SHH siRNA and the expression levels of three different miRNAs were compared between groups.
Results: Our results revealed that Hsa-miR-200a-5p expression was similar in both cell groups. Conversely, Hsa-miR-21-5p and Hsa-miR-9-5p were significantly upregulated in NCSCs. Further analysis showed that the knockdown of KLF4 did not significantly affect the expression levels of these miRNAs. However, silencing SHH resulted in a substantial downregulation of Hsa-miR-21-5p and a significant upregulation of Hsa-miR-9-5p. Additionally, Hif1a knockdown led to the downregulation of both Hsa-miR-21-5p and hsa-miR-9-5p.
Conclusion: These findings highlight the complex regulatory mechanisms of miRNA expression in different cellular contexts and suggest potential roles for these miRNAs in response to specific gene silencing.
Principles of Law in an integrative Legal Understanding (Yanaka Stoilov’s concept)
Authors: Ilyukhina Vera A.
Published: December 2024

General ideas about the principles of law in the concept of integrative legal understanding are characterized. The concept of principles of law developed by the Bulgarian scientist Yanaki Stoilov is analyzed. The position is substantiated that Ya. Stoilov’s concept fits into the integrative legal understanding. The views of Ya. Stoilov on the concept and essence of the principles of law, the functions and forms of the principles of law are characterized. It is concluded that the most original element of Ya. Stoilov’s concept is the introduction into scientific circulation and development of the category “form of principles of law”. On the one hand, this is an advantage of the scientist's work and allows us to classify his concept of the principles of law as integrative. On the other hand, ideas about the form of principles of law are also a “weak link” in Ya. Stoilov’s research due to the inclusion of legal and non-legal elements, which was precisely a consequence of the “integrativeness” of his approach to the problem field being studied. It is noted that to date, the concept of Ya. Stoilov is the only holistic doctrine of the principles of law from the position of integrative legal understanding.
Issues of legal counteraction to fraud related to fundraising for charitable activities
Authors: Trufanova Alexandra Yu. , Larionov Vyacheslav Yu.
Published: December 2024

The relevance of this topic is due to the fact that the development of society, the emergence of public organizations has led to the fact that in modern realities, fundraising for charitable activities is carried out, which, in turn, is not always carried out legally. The purpose of this study is to analyze crimes committed in the field of charitable activities of organizations and individuals and to determine measures of prevention and legal counteraction for this type of crime. To date, we are not yet talking about the effectiveness of the state system for preventing pseudo-charitable activities, we consider it necessary to develop legislative regulation of this area and ensure mandatory necessary retraining of law enforcement agencies to increase knowledge in the field of prevention, prevention and legal counteraction of fraud when raising funds for charitable activities. The methodology consists of dialectical, structural, formal legal and comparative legal methods, analysis and synthesis. As part of the study, we analyze the causes of crimes in the activities of charitable organizations, investigated the features of this type of crime, and proposed measures to prevent and counteract the corresponding crime. It is noted that legal mechanisms to combat pseudo-charitable activities are absent from the legislation due to the narrow specificity of this type of crime. Their solution is seen in the development of a set of prevention and counteraction measures, the identification of the corpus delicti in legislation and the creation of a special unit of law enforcement agencies.
The procedure for removing the legal status of “malicious violator of the established procedure for serving a sentence” from convicted persons: theoretical, legal and organizational aspects
Authors: Prokhorova Maria V. , Karetnikov Konstantin V. , Kovalev Nikolay S.
Published: December 2024

The object of the study is criminal enforcement legal relations related to such a legal phenomenon as the removal of the convicted person’s legal status as a “malicious violator of the established procedure for serving punishment” (hereinafter referred to as malicious status, the status of a malicious violator). the analysis of the legislative provisions regulating the procedure for removing the studied status from a convicted person is carried out. information is summarized on the practical activities of the administration of places of deprivation of liberty of the siberian federal district (hereinafter referred to as the sfd) aimed at implementing the procedure for removing the convicted person from malicious status. based on the results of the analysis of the legal norms and practice of the implementation of this institute, legal and organizational shortcomings are identified, and ways to solve them are proposed. the conducted research used methods such as a questionnaire survey, which consists in obtaining answers to the questions posed in the questionnaire from practical employees of places of detention. on their basis, objective conclusions are drawn about the existence of organizational problems in the activities of the administration of correctional facilities of the sfd, requiring a scientific approach to solving the legal phenomenon under study. the use of formal legal and comparative legal methods made it possible to formulate the shortcomings of the legal regulation of the removal of this status from a convicted person. we see the solution of legal and practical problems in the proposed sequential procedure for removing the convicted person from malicious status.
Oficina Libras + Matemática: Um Relato De Experiência Sobre O Seu Papel Social
Authors: Sedrim Gonçalves Francisca Aglaiza Romão , Brasil Matias Eduardo Waldmann , Joalison Santos da Silva  , Barros Amparo Luiz Augusto dos Santos , Thayssa Vitória Araújo de Souza
Published: December 2024

A constatação da falta de sinais da Língua Brasileira de Sinais (Libras) na área da matemática motivou a criação de uma oficina bilíngue na Universidade Estadual de Campinas, cujo nome foi Libras + Matemática. Após uma seleção de candidatos a partir de seus níveis de proficiência em Libras e interesse em matemática, Surdos estudantes de ensino médio de cinco estados brasileiros foram convidados a participar de doze dias de oficina, que teve não apenas aulas de geometria, mas também diversas atividades que estão além do currículo escolar. O presente trabalho em forma de relato de experiência busca detalhar os procedimentos da oficina. Após o relato, discutem-se algumas implicações da oficina sobre o seu papel social para os estudantes surdos e comunidades acadêmica e surda, sugerindo o que foi percebido positivamente por ambos os grupos.
Evaluation of Force Degradation of the Niti Open Coil Spring After Exposure to High and Low Temperatures, in Vitro Study
Authors: Abdulqawi Abdulghani Ali , Galvan Shirchie Iris P.
Published: December 2024

Open coil springs are designed to provide expansion force, as indicated in the opening spaces. The super elasticity of Niti arch wires and springs allows the orthodontist to apply almost continuous light force with larger activations, resulting in reduced tissue trauma. However, indirect factors like high or low temperature should be monitored as an essential part of applying any force using open coil springs. These temperature differences may influence the springiness, corrosion, and efficacy of Niti coil springs over time. The aim of this study was to evaluate the force rate of NITI open coil springs compressed from 15.0 mm to 8.5 mm after exposure to high (45 ± 3 °C) and low temperature (10 ± 3°C). Forty-five samples of 15.0 mm long Niti springs were divided into 3 groups (n = 15). Group A was immersed in artificial saliva at 37º C for 21 days. Group B was immersed in hot water (45± 3 °C). Group C was immersed in cold water (10± 3 °C). The springs were then subjected to a compression test using a Manual Digital Force Gauge at 43% of the initial size (pre-stretched). Subsequently, the springs were compressed from 15.0 mm to 8.5 mm, and the data were recorded at Day 0, 1, 10, and 21. The analysis of variance revealed p-values below 0.05 for the four-time frames: initial test (0.046), after 24 hours (0.007), after 10 days (0.082), and after 21 days (0.038), indicating significant differences in the force rate of Niti open coil springs when immersed in different temperatures. Additionally, significant differences were found among the different pairings of the three tested groups. The force rates of open coil springs with low temperature were statistically different across different time frames. However, high temperature affected the coil springs more significantly than low temperature. There were significant differences in the force rate of Niti open coil springs when immersed in different temperatures.
Sero-prevalence of Hepatitis C infection among the Municipal Waste collectors in Aden, Yemen
Authors: Gubran Ali N.M. , Altuhaish Adeel Abdulkarim Fadhl , Waleed Hana , Abdullah Aisha  Ali , Ali Ayat  Gamal , Saeed Bona  Mohammad , Omar Nadrah  Aidroos , Abdullah Nawras  Hamza  , Saeed Doa'a  Anwer  Mohammed , Naji   Taha Abdo Ali , Taleb Adel Gamal Abdulrab , Manea Fatima Adel Mohammed , Mohammed Fatima Mohammed Abdulhameed , Awadh Fatima Mohammed Ghaleb , Nasr Gamilah Nasser Rageh , Ben Mohammed Mustafa Nadhmi Mohammed , Al-labni Mohammed Abdullah
Published: December 2024

Objectives: Hepatitis C virus infection is major global health problem. The present study was aimed to determine the prevalence of Hepatitis C infection among municipal waste collectors and to identify clinical findings and risk factors associated with HCV infection among those collectors in Aden, Yemen. Methods: A cross-sectional study was conducted on 100 municipal waste collectors. The blood samples were collected from all MWCs, then the clotted blood was separated by centrifuge and the sera were tested for presence of HCV antibodies (Anti-HCV) by  Cobas technique that based on ECLIA. Results: Out of 100 municipal waste collectors, majority was males 89(89/100). The total mean age of those members was 36.74±10.98years. The range of ages was 16 and 60 years. Only 1(1/100) had HCV infection. This case was male, married and within age group ≥ 45years which comprised; 1.1%, 1.2% and 4.5%, respectively. The positive case was illiterate and had low economic status and had duration of work as municipal waste collector from 10-20years and alone accommodation which comprised 1.1%, 1.6% 2.4% and 9.1%, respectively. This 1(7.8%) HCV infected patient infection lives in Al-Muallhe. Significant associations found between HCV infection and exposing to blood transfusion, catheterization and needles stick as risk factors (p=0.002,0.0001 and 0.080), respectively and liver cirrhosis as complicated clinical finding (p=.0001),but the association was not significant between HCV infection and sources of waste (0.620).
Conclusion: It can be concluded from this study that the municipal waste collectors in Aden, Yemen had lower rate of HCV infection than most studies globally. The males, married and MWCs in age group≥ 45years, and those had illiterate education and live alone had highest percentages of HCV infection. Blood transfusion, needles stick and catheterization may increase the risk of HCV infection.