bluuebunny/crossref_metadata_2025 huggingface dataset:
Cementless Hip Implants: History and Current Status of the Issue
Authors: Shubnyakov I. I. , Riahi A. , Shubnyakov M. I. , Denisov A. O. , Khujanazarov I. E. , Tikhilov R. M.
Published: July 2020

Background. Total hip arthroplasty is an effective type of surgery with excellent survival rates of modern implants. From the very beginning of the widespread introduction of total hip arthroplasty, the cement technique of components fixing prevailed. However, many researchers associated the development of osteolysis and the following loosening with the reaction to cement. The subsequent studies clarified the situation regarding the nature of osteolysis, but there remained the problem of insufficient stability of the cemented stems to withstand the penetration of polyethylene wear particles into the distal part of the stem with the development of loosening. An ideal endoprosthesis should ensure the normal hip biomechanics, joint painless functioning and improve the quality of life of the patient without the need for revision. The optimal results of cementless femoral stems functioning depend on the achievement of initial stability, osseointegration and equable transmission of tension onto the femur. There are many factors that influence osseointegration processes and the subsequent behavior of the implant. Understanding these factors is the key to choosing the optimal implant for a particular patient, taking into account the anatomical features of the femur.The purpose of this article is to discuss upon the literature review the application of cementless femoral components, the possible causes of failure and its prevention from the point of view of the evidence-based practice.Materials. The search was conducted in the PubMed, eLIBRARY databases and through the Web of Knowledge. Survival rates and prevalence of various implants in the structure of primary arthroplasty were estimated on the basis of annual reports of a number of national registries, as well as the hip arthroplasty registry of the Vreden National Medical Research Center of Traumatology and Orthopedics. Among the factors discussed are the properties of the components material, the form of the implants, surface properties, and the influence of the anatomical features of the femur. Additionally, the most used types of cementless femoral components were assessed.Conclusion. Cementless femoral components demonstrated the excellent long-term survival and functional results. The currently prevailing type of the prosthesis intimate attachment to the bone is the biological fixation, especially in groups of young patients. Future studies of cementless implants should necessarily take into account the patient’s age, level of activity, type of bone canal, the presence of deformities, and the friction pair used. This will make it possible to draw clearer conclusions in what clinical situation it is advisable to use the femoral components of a particular design.
Trauma Care in COVID-19 Pandemic
Authors: Sitnik A. A. , Murzich A. E. , Volotovski P. A. , Gerasimenko M. A.
Published: July 2020

The development of COVID-19 pandemic is the serious challenge for trauma care systems across the world. Recommendations on general principles of trauma care in the settings of pandemic, medical stuff protection and prevention of the spread of infection based on the data from international centers are presented in the article. Delay of all elective cases, restriction of surgical treatment of fractures with relative indications for surgery are recommended. The segregation of cases into COVID-19 confirmed or suspected and COVID-19 negative patients is important. When possible before the admission to in-patient department the patient shall be tested on COVID-19. When the COVID-19 status of the patient is unclear all possible protection measures shall be used: patient isolation and medical stuff protection. To prevent the spread of infection it is recommended to split the stuff of the traumacenter into 2 or 3 groups. Each of the groups is working during the week with subsequent period of the self-isolation (remote work) for the period of 1-2 weeks (according to the duration of incubation period of the COVID-19). During the surgical treatment the most dangerous stages of the surgery are endotracheal intubation / extubation and also aerosol-generative procedures: electrocoagulation, pulsed wound lavage, drilling, the use of oscillating saw and medullary reaming. The stuff in the OP-theatre has to be accordingly equipped (personal protection equipment). The risk factors for the medical stuff are fatigue from overwork, the absence of real-time training in infection-prevention measures and non-compliance with PPE.
THE THE ASSOCIATION BETWEEN WHO CLINICAL STAGE AND OTHER RISK FACTORS WITH PULMONARY TUBERCULOSIS AMONG PEOPLE LIVING WITH HIV/AIDS: A CROSS-SECTIONAL STUDY
Authors: SURYANA KETUT , SUHARSONO HAMONG , JOENPUTRI NOVIANA
Published: July 2020

Objective: To estimate the Pulmonary Tuberculosis (PTB) prevalence among the participants/People Living With HIV/AIDS (PLWHAs) and to verify the association between WHO clinical staging and other risk factors with PTB.

Methods: A cross-sectional study was conducted to estimate the PTB prevalence. Probable associated risk factors in PLWHAs with and without PTB were compared. The association between WHO clinical staging and other risk factors with PTB was investigated using bivariate analysis. A p-value<0.05 was considered statistically significant.

Results: This study was conducted from January 2018 to December 2019, recruited about 584 participants with presumptive PTB and 20.72% (121) confirmed with PTB. In the bivariate analysis; participants who are on human immunodeficiency virus (HIV) Stage 4 (WHO clinical staging) were significantly more likely to develop PTB (p=0.000). PTB was significantly higher among male than female (p=0.000), higher among the older (p=0.030). PTB was significantly more frequent among participants with lower cluster differentiation 4 (CD4) cell counts (p=0.042). A contact history with a Tuberculosis (TB) patient was an important risk factor (p=0.000). PTB was significantly associated with smoking history (p=0.000).

Conclusion: A high PTB prevalence was observed. There was a significantly association between the severity of WHO clinical staging, sex, age, lower CD4 cell count, a contact history with a tuberculosis (TB) patient and smoking history with PTB among PLWHAs.
The DESIGN AND DEVELOPMENT OF CARVEDILOL GASTRORETENTIVE FLOATING DRUG DELIVERY SYSTEMS USING HYDROPHILIC POLYMERS AND IN VITRO CHARACTERIZATION
Authors: MOHAPATRA PRASANTA KUMAR , SATYAVANI C. H. , SAHOO SATYAJIT
Published: July 2020

Objective: The primary aim of the present examination was to create carvedilol phosphate floating tablets using factorial designs and for retention in the upper portion of the gastrointestinal (GI) tract to sustain the dissolution where the solubility of carvedilol phosphate is more in an acidic medium.

Methods: The floating tablets of carvedilol phosphate were ready to employ different concentrations and a combination of these polymers of Na-alginate, Carbopol 934P, and sodium carboxymethyl cellulose (NaCMC) with lubricants magnesium stearate by direct compression technique. In the present experiment, involved sodium bicarbonate and citric acid as a gas-producing agent. Fifteen formulations structured and judged for pre-compression components like the angle of repose, bulk and tapped density, Hausner’s ratio, compressibility index, and post-compression factors are weight uniformity, hardness, drug content, friability, in vitro buoyancy, dissolution studies, and Fourier transforms infrared spectroscopy (FTIR).

Results: The drug released 90.02% in 12 h by combining NaCMC (7.5 mg) and Na-alginate (7.5 mg) in the formulation F14 towards the achievement of sustained release. Batch F14 selected as optimized, as provided desired zero-order release profile as well as floating lag time 20 s and total floating time>12 h, and the mechanism of drug release observed (n = 1.098, super case-II transport).

Conclusion: From the results fulfilled that all the preparation found to be within the pharmacopeia limits and was the best dosage form to treat moderate heart failure and hypertension. The in vitro dissolution profiles of all formulations placed into various kinetic models, the statistical parameters like slope, regression coefficient and intercept determined. The gastro-retentive dosage form to maintain the sustain drug delivery, which would improve the maximum therapeutic efficacy and patient compliance.
MICRO TEACHING COURSE: Does it affect students' teaching ability?
Authors: Muluk Safrul , Habiburrahim Habiburrahim , Ardiansyah Ardiansyah
Published: July 2020

This explanatory quantitative study aimed to identify the correlation between the students’ Micro Teaching and Field Pre-Service Teaching courses. The population of the study was the students of English Education Department of the Faculty of Education and Teacher Training Universitas Islam Negeri (UIN) Ar-Raniry, Banda Aceh, Aceh, Indonesia, who had taken micro-teaching class and had conducted field pre-service teaching, a total of 141 students. Then, 43 students were selected as the sample of this study. Data came from these students’ scores in Micro Teaching class and in Field Pre-Service Teaching. The data were analyzed by using Pearson Product Moment with the SPSS 16.0. The findings indicated that there was no significant correlation between micro-teaching and field pre-service teaching (p-value = .196; p>.05). In addition, the strength level of the Pearson correlation coefficient between the two variables was negative and weak (r = -0.201). It can be interpreted that the students’ teaching ability was not dependent upon their micro-teaching scores.
WDFY2 Potentiates Hepatic Insulin Sensitivity and Controls Endosomal Localization of the Insulin Receptor and IRS1/2
Authors: Zhang Luyao , Li Xue , Zhang Nan , Yang Xin , Hou Tianyun , Fu Wan , Yuan Fengjie , Wang Lina , Wen He , Tian Yuan , Zhang Hongquan , Lu Xifeng , Zhu Wei-Guo
Published: July 2020

Endosomes help activate the hepatic insulin-evoked Akt signaling pathway, but the underlying regulatory mechanisms are unclear. Previous studies have suggested that the endosome-located protein WD repeat and FYVE domain–containing 2 (WDFY2) might be involved in metabolic disorders, such as diabetes. Here, we generated Wdfy2 knockout (KO) mice and assessed the metabolic consequences. These KO mice exhibited systemic insulin resistance, with increased gluconeogenesis and suppressed glycogen accumulation in the liver. Mechanistically, we found that the insulin-stimulated activation of Akt2 and its substrates FoxO1 and GSK-3β is attenuated in the Wdfy2 KO liver and H2.35 hepatocytes, suggesting that WDFY2 acts as an important regulator of hepatic Akt2 signaling. We further found that WDFY2 interacts with the insulin receptor (INSR) via its WD1–4 domain and localizes the INSR to endosomes after insulin stimulation. This process ensures that the downstream insulin receptor substrates 1 and 2 (IRS1/2) can be recruited to the endosomal INSR. IRS1/2-INSR binding promotes IRS1/2 phosphorylation and subsequent activation, initiating downstream Akt2 signaling in the liver. Interestingly, adeno-associated viral WDFY2 delivery ameliorated metabolic defects in db/db mice. These findings demonstrate that WDFY2 activates insulin-evoked Akt2 signaling by controlling endosomal localization of the INSR and IRS1/2 in hepatocytes. This pathway might constitute a new potential target for diabetes prevention or treatment.
DW14006 as a Direct AMPKα Activator Ameliorates Diabetic Peripheral Neuropathy in Mice
Authors: Xu Xu , Wang Wei , Wang Zhengyu , Lv Jianlu , Xu Xiaoju , Xu Jiawen , Yang Juanzhen , Zhu Xialin , Lu Yin , Duan Wenhu , Huang Xi , Wang Jiaying , Zhou Jinpei , Shen Xu
Published: July 2020

Diabetic peripheral neuropathy (DPN) is a long-term complication of diabetes with a complicated pathogenesis. AMP-activated protein kinase (AMPK) senses oxidative stress, and mitochondrial function plays a central role in the regulation of DPN. Here, we reported that DW14006 (2-[3-(7-chloro-6-[2′-hydroxy-(1,1′-biphenyl)-4-yl]-2-oxo-1,2-dihydroquinolin-3-yl)phenyl]acetic acid) as a direct AMPKα activator efficiently ameliorated DPN in both streptozotocin (STZ)-induced type 1 and BKS db/db type 2 diabetic mice. DW14006 administration highly enhanced neurite outgrowth of dorsal root ganglion neurons and improved neurological function in diabetic mice. The underlying mechanisms have been intensively investigated. DW14006 treatment improved mitochondrial bioenergetics profiles and restrained oxidative stress and inflammation in diabetic mice by targeting AMPKα, which has been verified by assay against the STZ-induced diabetic mice injected with adeno-associated virus 8–AMPKα–RNAi. To our knowledge, our work might be the first report on the amelioration of the direct AMPKα activator on DPN by counteracting multiple risk factors including mitochondrial dysfunction, oxidative stress, and inflammation, and DW14006 has been highlighted as a potential leading compound in the treatment of DPN.
Body Weight Variability and the Risk of Cardiovascular Outcomes and Mortality in Patients With Type 2 Diabetes: A Nationwide Cohort Study
Authors: Nam Ga Eun , Kim Wonsock , Han Kyungdo , Lee Chung-woo , Kwon Yeongkeun , Han Byoungduck , Park Seokwon , Park Joo-Hyun , Kim Yang-Hyun , Kim Do-Hoon , Kim Seon Mee , Choi Youn Seon , Cho Kyung Hwan , Park Yong Gyu
Published: July 2020

OBJECTIVE

Obesity and type 2 diabetes are risk factors for cardiovascular diseases and mortality, and they commonly result in weight variabilities. We aimed to investigate the association between body weight variability and risk of major cardiovascular outcomes and mortality in individuals with type 2 diabetes using large-scale, nationwide cohort data on the Korean population.

RESEARCH DESIGN AND METHODS

We enrolled 624,237 individuals with type 2 diabetes who underwent health examinations provided by the Korean National Health Insurance System between 2009 and 2010, with three or more body weight measurements within 5 years since enrollment and followed up until the end of 2017. We assessed body weight variability using four indices, including variability independent of the mean (VIM). A multivariate-adjusted Cox proportional hazards regression analysis was performed.

RESULTS

During the follow-up, 15,832, 25,038, and 44,716 cases of myocardial infarction (MI), stroke, and all-cause mortality, respectively, were recorded. Body weight variability was associated with increased risks of major cardiovascular outcomes after adjusting for confounding variables. Compared with the hazard ratios (HRs) of the lowest quartile group, the HRs (95% CIs) of the highest quartile group of VIM for body weight were 1.15 (1.10–1.20), 1.22 (1.18–1.26), and 1.58 (1.53–1.62) for MI, stroke, and all-cause mortality, respectively.

CONCLUSIONS

Body weight variability was associated with increased risks of MI, stroke, and all-cause mortality in patients with type 2 diabetes and may be a predictor of cardiovascular outcomes in such patients. Appropriate interventions to maintain stable weight could positively influence health outcomes in patients with type 2 diabetes.
Frequency Plan Optimization Based on Genetic Algorithms for Cellular Networks
Authors: Megnafi Hicham
Published: July 2020

Cellular networks are constantly evolving to ensure a better Quality of Service (QoS) and quality of coverage ever more important. The radio cellular systems are based on frequency allocation. In this context, frequency allocation principle consists in choosing an optimal frequency plan to meet traffic demand constraints and communication quality while minimizing the radio interferences. This paper proposes an optimal frequency allocation approach based on genetic algorithms to minimize co-channel and adjacent channel interference. The validation of this new approach is conﬁrmed by the results of the work we have done in the GSM network. In fact, we used the ﬁle obtained by the OMC-R, which deﬁnes the adjacent cells of each cell and the frequencies allocated to the considered area. The results obtained clearly show the effectiveness and robustness of the approach used.
Analisis Kriteria dan Bobot untuk Penentuan Lokasi Jalan Pertanian di Provinsi Jambi
Authors: Daulay Asnelly Ridha
Published: July 2020

Jalan pertanian sangat dibutuhkan untuk lalu lintas pengangkutan sarana produksi pertanian dan hasil panen. Namun, proses seleksi lokasi untuk pembangunan jalan tersebut dilakukan secara subjektif, tanpa kriteria  yang baku dan kerap dilatari kepentingan politis. Penelitian ini bertujuan menggali kondisi eksisting pembangunan jalan pertanian di Provinsi Jambi, termasuk gambaran partisipasi masyarakat untuk merawat jalan tersebut, serta menyusun kriteria dan bobotnya masing-masing untuk penentuan lokasi pembangunan jalan pertanian. Pengumpulan data dilakukan melalui observasi, wawancara mendalam, serta studi pakar. Data-data ini kemudian dianalisis menggunakan Simple Multi Attribute Rating Technique (SMART). Hasil penelitian menunjukkan bahwa terdapat delapan masalah utama terkait jalan pertanian di Provinsi Jambi yaitu konstruksi model, perawatan, pemanfaatan, konektivitas, pendanaan, alih fungsi lahan pertanian, daya tahan, dan pola pengerjaan jalan pertanian. Terdapat 4 kriteria yang dikembangkan sebagai pertimbangan dalam menentukan lokasi jalan pertanian dengan bobot masing-masing sebagai berikut: lokasi (0,23), kelembagaan/kelompok tani (0,36), kualifikasi kebun/sawah (0,24) dan sharing perawatan jalan pertanian (0,17).
Pengaruh Aplikasi Blower dan Tipe Pengemasan Terhadap Mutu Cabai Rawit Segar (Capsicum frutescens linn) selama Transportasi
Authors: Lutfi Musthofa , Prasetyo Joko , Pujianti Irma Putri , Maharani Dewi Maya
Published: July 2020

Cabai rawit adalah salah satu produk hortikultura yang memiliki nilai ekonomis tinggi namun mudah mengalami kerusakan/layu selama proses pengemasan dan tranportasi. Tujuan penelitian ini adalah untuk mengetahui pengaruh aplikasi blower dan tipe pengemasan yang paling aman selama proses transportasi terhadap mutu cabai rawit segar berdasarkan perubahan suhu, kerusakan mekanis, susut bobot, kadar air, dan kekerasan cabai. Metode penelitian eksperimental yang digunakan adalah RAL (Rancangan Acak Lengkap) dengan 2 perlakuan. Perlakuan pertama dalam 2 taraf, yaitu dengan blower dan tanpa blower. Sedang perlakuan kedua adalah tipe pengemasan dalam 3 taraf, yaitu kemasan karung, keranjang, dan kardus. Tiap sampel diisi cabai rawit sebanya 4 kg. Dari kombinasi kedua perlakuan tersebut diperoleh 5 perlakuan dengan 3 kali ulangan. Data yang diperoleh dari penelitian ini dianalisis dengan Analisis Varians dan dilanjutkan dengan Uji BNT (Beda Nyata Terkecil) 5 %. Hasil penelitian menunjukkan bahwa aplikasi blower dan tipe pengemasan menunjukkan perbedaan yang tidak nyata (P<0.05) terhadap kerusakan mekanis dan kadar air cabai rawit segar, tetapi aplikasi blower dan tipe pengemasan menunjukkan perbedaan yang nyata (P>0.05) terhadap susut bobot dan kekerasan. Kesimpulan dari penelitian ini adalah penggunaan blower dan jenis pengemasan kardus merupakan kombinasi perlakuan yang paling aman selama simulasi transporasi dengan rata-rata nilai kerusakan mekanis 1.27 %, susut bobot 0.54 %, kadar air 0.76 %, dan kekerasan 1.57 kgf/cm2.
Kajian Etnopedagogi Terhadap Yoga Sebagai Tradisi Bali
Authors: Tristaningrat Made Adi Nugraha
Published: July 2020

Teaching yoga is not a teaching which is concerned specifically about the teachings of a particular religion or belief. Yoga literally comes from the word “yuj” which means uniting or connecting with God. Yoga is basically a means or way of life, not something out of life, is not it also distanced itself from the activities, but rather is an efficient performance by the true spirit of life. Yoga nor run away from home and habits of human life, but instead is a process of the formation of attitude to life at home (family) as well as social life with order and tradition that followed included also in the scope of Balinese tradition in particular. Yoga in the tradition of Bali are reflected in all the viable commonplace example done in Yoga known there is a term which is a type of yoga Asanas in terms of movement both in the standing position, sitting, and lying down. Asanas indirectly has done in a civic order Bali through sitting cross-legged when visited, lined up neatly, to carry out the process of worship that uses or standing cross-legged stance. This behavior does not necessarily constitute the heritage of our Yoga Science adoption directly or indirectly in everyday life, but it is an idea that something that reflects the local wisdom has the feel a clear education as a meaningful review.
Prana Dan Gaya Hidup : Upaya Meningkatkan Energi Vital Tubuh
Authors: Rahmawati Putu Reny
Published: July 2020

Pranayama is breath control in yoga. Pranayama controls prana (vital energy) in the body, with the controlled and controlled withdrawal and exhalation resulting in increased vital energy so that it can influence the mind more calmly and the body more healthy. By doing the practice of Pranayama and making it a lifestyle in the present or the modern era, it can make a person more healthy and have a much better mind. Some pranayama practices that can be done are: Suryabedha Pranayama, Sitali Pranayama, Sitkari Pranayama, Ujayi Pranayama, Bashrika Pranayama, Kapalabhati Pranayama and many more Pranayama with different benefits according to the needs of yoga practitioners and remain in increasing vital energy in the body
Hakikat Budaya Jawa Kaitannya dengan Agama Hindu di Bali
Authors: Poniman Poniman
Published: July 2020

The existence of Balinese culture has taken place in the presence of foreign influences. Similarly, when Hinduism and Buddhism were embraced by Balinese people. It also affects Hinduism in Bali, which until now seems dominant and gives a hue and coloring the culture and life of Balinese people. Until now, the existence of the Religion and Culture of Bali faced global challenges, the challenges of materialism, and even the impact of the development of Social Media influenced Balinese culture. Knowing the Nature of Javanese Culture in relation to the development of Hinduism in Bali forms the character of Balinese Hinduism which eventually becomes the Balinese Culture. Hinduism in Bali is more visible in Adat and Tradition, this is due to the formation of Religion as a real-life practice. So that the existence of Hinduism is not clearly seen with the Wedanya book as the guiding basis but Lontar-Lontar which is used as a practice in adat both in rituals and literature so it is not found when religious events use Vedas as reading material in Pura and in ritual guidelines.
Tari Sandar sebagai Benteng Pertahanan Adat di Desa Adat Kedonganan Kuta
Authors: Sudarsana I Made
Published: July 2020

Performing art in Bali is a cultural repertoire that is very tied to the diversity of forms and goals. The island of Bali, dubbed the Island of the Gods, Khayangan Island (Island of Paradise) has a variety of dances that vary in shape and have a close relationship with the implementation of Hindu religious ceremonies which are the largest in number in Bali. The attraction of Bali is its unique culture, community life and natural beauty. Its cultural life is the unification of religion, culture, harmonious customs, taste and intention as a prominent element of human cultivation taking the form of religion, aesthetics and ethics. This is reflected through cultural arts, solidarity of mutual cooperation as a sense of togetherness.

As a tradition, the existence of Balinese art is in line with all aspects of life. In an integrated manner, reflecting on the ideals of the supporting community is not excessive if the Balinese people consider that art (dance, gamelan and wayang) is an integral part of their lives which is always bound by ritual events. Hinduism which has rational, ritual, emotional and belief elements often makes the art as a ritual drama a means to strengthen trust and formulate religious conceptions in people’s lives.
Taksu Dalam Kehidupan Berkesenian Masyarakat Bali
Authors: Juni Ngakan Ketut
Published: July 2020

Taksu believed as a force capable of bringing success in a job. For communities and artists of Bali taksu, believed to be the saving grace of Ida Sang Hyang Widhi Wasa through its manifestation as Sanghyang Taksu. Sanghyang Taksu revered in a special holy place calledor palinggih Taksu. Taksu can be obtained devote always someone with Him. Besides taksu in a person can also be raised by way of keeping morality, honesty, chastity through yoga.
Konsep Kepemimpinan Catur Kotamaning Nrepati Dalam Kakawin Niti Sastra
Authors: Giri I Putu Agus Aryanaya
Published: July 2020

Actually, the societies want a figure of leader that has credibility, social life, and can protect and guide the societies well. However the reality is, nowadays there are many leaders who are not trusted by the societies because of their negative behavior. Talking about this phenomenon, actually Hinduism has produced various kinds of doctrines about the philosophy of life especially about leadership since many years ago. Unfortunately that doctrine has not been known and applied in maximum way. Kakawin Niti Sastra is one of classical Hindu literature that has full values of leadership and it shall be used as source of research. The structures of leadership in Kakawin Niti Sastra consists of Prabhu, Purohita, Amatya, Nāradhipati, Sena and Sanggya. Catur Kotamaning Nrepati leadership Concept in Kakawin Niti sastra consists of the value of wisdom (jnana wisesa suddha), compassion (kaprahitaning praja), bravery (kawiryan), and authority (wibhawa).
Transformasi Simbol-Simbol Teologis Yang Sakral, dari Ritual ke Serimonial, dari Formal ke Formalitas Semu {Kajian Hipersimiotika Religius dalam Ritual Hindu}
Authors: Donder I Ketut
Published: July 2020

Transformation or change is a necessity; it is very clearly described in Vedanta theories, such as Trikona’s theory; Jantra theory and Caturyuga theory. Trikona’s theory and Jantra’s theory describe that everything that exists is materially invisible, it is seen only in the middle, and then it will be invisible. Over time, after being invisible, it will be re-created so that it is seen again for a certain period of time, after which it is lost back from sight. This happens continuously unceasingly like a jantra (circle), so transformation is something that can not be avoided by anyone and anyone.
The transformation in Caturyuga’s theory presupposes the universe and its contents as a four-legged table for one yuga (age); then on the authority of the Time, all changed. Change is described as the turn of the times, the
universe of the table, gradually ignoring the legs one by one. Finally, the longer the table becomes more unstable until it collapses to the floor. Identical to that allegory, the reality of today’s society shows its sacred attitude increasingly propane; the appreciation of the sacred is getting worse, the taksu is getting weaker, and the more holiness loses value.
Religious teachings today seem to appear just as lip ornaments only, attributes of spirituality also appears as a mere accessory only. All of things more lost the meaning of authenticity, so that falsehood becomes a very
popular tradition today. Today’s modern human attitudes seem to conform to the term ‘musang berbulu domba’, or ‘harimau berjubah’, or ‘singa berdasi’; humans are increasingly shameless; something sacred to be made merely ceremonial, the formal being made into a mere formality. This is a reality that is hyper-reality to make good people becoming pensive full of questions.
PENGATURAN PENDUDUK PENDATANG (KRAMA TAMIU ) DI TINJAU DARI HUKUM ADAT BALI
Authors: Kantriani Ni Ketut
Published: July 2020

The problems caused by the influx of migrant population (Krama Tamiu) is the presence of immigrants who often do not report to the Village Prajuru, Head of the Environment and lack understanding of the rights and duties of the residence. In Balinese customary law is generally regulated about Krama Tamiu which is contained in Awig-awig Desa Adat / Desa Pakraman. Immigrants (Krama Tamiu / Tamiu) entering other areas, must know and follow the rules, as there is a convention between rights and obligations to be obtained and implemented. The immigrant population (Krama Tamiu) will receive a guidance (pasayuban) in the form of security guarantees, relief from all kinds of dangers that may occur during the respective stay in the region. As compensation for the rights it receives, the migrant population (Krama Tamiu) is subject to certain obligations whose type and form varies according to Awig-awig Desa Adat.
DAMPAK TERHADAP ANAK DALAM PERKAWINAN PADA GELAHANG DI DESA PAKRAMAN TANGGAHAN PEKEN, DESA SULAHAN, KECAMATAN SUSUT, KABUPATEN BANGLI
Authors: Kamariani Ni Kadek , Kantriani Ni Ketut , Januariawan I Gede
Published: July 2020

caused by several factors, both heredity and even social factors. From these factors cause future impacts on the couple themselves and even on children born. Based on the background above, the problem discussed in this study is the impact on children in Marriage to Gelahang in Pakraman village, Tanggahan Peken, Sulahan Village, Susut District, Bangli Regency. Data collection in this research uses observation, interview and literature study techniques. The research location was set in the village of Pakraman Tanggahan Peken, Sulahan Village, Susut District, Bangli Regency. The Occurrence of Marriage to Gelahang in the village of Pakraman Tanggahan Peken because there are two factors, namely heredity and social factors, where these factors have an impact on children for the future. The resulting impact is a psychological impact, where the existence of Marriage to Gelahang causes pressure on children, both mentally, such as the unpreparedness of children to carry out double obligations when implementing Marriage to Gelahang with different banjar / village and
physically, where when the child is siblings with many obligations that must be fulfilled, where both obligations cannot be abandoned, it causes physical pressure and even financial pressure for the child. In addition to psychological effects, marriage to Gelahang also causes social impacts, because there is
no regulation on marriage that raises questions from the community why the obligations undertaken in the village and in the banjar are the same as a married couple who carry out ordinary marriages.Besides that, in family law there are two impacts, positive and negative. And the last is the inheritance system, where having one child will have an impact on the heirs or successors in the future.
Masyarakat dalam Perkembangan Teknologi Informasi dan Realitas Perubahan Sosial di Era Postmodern
Authors: Maharani Ida Ayu Kartika
Published: July 2020

At present social changes that occur in the information revolution era, not only touch the appearance of government officials, politicians, and economic actors, but have penetrated the lifestyle and social behavior in the wider community, including the lifestyle and social behavior of young people. The existence of young people in the process of change and reform movement, is stated as one of the strengths of civil society that seems to be more easily adapted to the development of digital-based information and communication technology that is developing in digital native circles.
The development of a society that is dominated by information technology, in addition to changes in social interaction patterns and ways of communicating, there have also been changes in people's attitudes and behavior in responding to the social realities that occur around them. This reality is not merely an observable object, but has gone beyond reality itself which is called hyperreality. Hyperreality intended here is an artificial or superficial reality, created through the aid of simulation technology and imaging engineering, which takes over the natural world of reality. These are said to be models of reality, which have no reference to reality or do not have a reference or reference to reality, but only refer to themselves.
Mawewangsalan sebagai Media Komunikasi Masyarakat Abang Batu Dinding Kecamatan Kintamani Kabupaten Bangli
Authors: Yudhasatya Dharma I Wayan , SM Ulio
Published: July 2020

Human life cannot be separated from a communication, because human is a social creature whose lives depend on one another and communication is an intermediary between humans with one another. Through communication the attitudes and feelings of a person or group of people can be understood by other parties. In proportion to communication and language, a culture called Mawewangsalan emerged, which of course contained both elements, namely the use of language in communication systems as outlined into an art, namely the art of spoken words. Mawewangsalan culture is found in Abang Batu Dinding Village, Kintamani District, Bangli Regency. Mawewangsalan related to the form and nature in communication community in Abang Batu Dinding are two sentences that experience reduplication (lengkara kalih palet). The first sentence is like an insinuation, about heart of someone who says it, but has a hidden meaning behind words that are said. The second sentence is the true meaning of intend words. based on its nature Mawewangsalan can be divided into three, namely are jokes, advice, and figures of speech.
The process of communication in Mawewangsalan conducted by the community in Abang Batu Dinding Village takes place in every situation and every place in the community's social environment. Mawewangsalan as a form of communication process in life of the community of Abang Batu Dinding Village has communication elements namely communicator, verbal code, and non-verbal code. In community of communication Mawewangsalan in Abang Batu Dinding Village has a cognitive impact, because in Mawewangsalan there are several things of educational values are contained. Affective effects also occur in this authority because it is able to influence attitudes and paradigm of people. As well as the impact of behavior is the next impact associated that changes in community behavior caused by the process of Mawewangsalan in the social life of the community.
Religious identity in the modern digital world
Authors: Fedorova Marina
Published: July 2020

The subject of this research is the religious identity of Russian youth in the conditions of modern digital society. The author analyzes the factors of transformation of identification processes, examines the characteristics of religious identity, as well as defines the specificity of religious discourse within the Internet environment. The author believes that the main cause of the changes in religious consciousness and identity becomes rapid digitalization of all spheres of social life. This problematic gains relevance during the COVID-19 pandemic, forced self-isolation and transition towards remote work using the information and communication technologies. The author assumes that religious identity should be viewed from the perspective of its inclusion into a broader phenomenon – cyberidentity. An original definition of cyberidentity is proposed. The key factors of its formation, such as social networks and messengers, computer gamed, Internet memes, etc. are determined. The article leans on the analysis of information from websites of religious organizations, different groups in social networks, messengers and video hosting. The main source form empirical data became the results of large-scale research of dynamics of value orientations of youth of Nizhny Novgorod Region that was carried out from 2006 to 2019. The author concludes that currently it may appear that secular trends are growing, while the interest of youth in religion declines. This is conferment by the data acquired from mass surveying, interviewing, and analyzing the content of social networks. However, secularization processes have contradictory, nonlinear and unpredictable character. Within the Internet space, the dialects of religion and secular not just being retained, but reflected in the categories of digital society. In the digital post-secular society, religious identity becomes a part of the more global identification processes. It sets particular goals for the traditional religions, which are forced to adapt to civilizational challenges.
Direct Monitoring of Bicarbonate Transport by Emission Spectroscopy
Authors: Martínez-Crespo Luis , Hewitt Sarah , Alessandro De Simone Nicola , Sindelar Vladimir , Davis Anthony P. , Butler Stephen , Valkenier Hennie
Published: July 2020

The transmembrane transport of bicarbonate is a key step in many important biological processes, while problems with bicarbonate transport are at the origin of various diseases. Over the past 10 years, many anionophores that have been developed for the transport of chloride, have also been tested as bicarbonate transporters. However, methodology to directly monitor the kinetics of transport of bicarbonate is lacking, hence indirect methods have been used, which mainly rely on the monitoring of chloride concentrations.Here we present an assay that allows the kinetics of bicarbonate transport into liposomes to be monitored directly, using emission spectroscopy. The assay utilises an encapsulated europium(III) complex, which exhibits a large increase in emission upon binding of bicarbonate. The advantages of this assay over existing methodology are that concentrations of bicarbonate are monitored directly and with a high sensitivity. This allows studies at very low concentrations of anionophores, and for the mechanisms of bicarbonate transport to be unravelled. We have distinguished classical antiport with bicarbonate from mechanisms involving CO2 diffusion and the dissipation of a pH gradient. Furthermore, the use of a standard fluorescence spectrometer and liposomes with a diameter ~200 nm makes this assay readily and reliably applicable in many laboratories, where it can facilitate the development of bicarbonate transporters for applications in physiological studies or therapies.
Antistressor effect of Costus speciosus on noise induced immunological changes in rats
Authors: Saraswathi Ilango  , Saikumar P  , Sembulingam K  , SaiKarthik Jayakumar
Published: July 2020

Costus speciosus is being widely used in Indian folk medicine for treating various disorders. Environmental noise pollution is supposed to be an important factor for many health problems and it causes immune abnormalities. In the present study immune-regulating potential of Costus speciosus extract was evaluated during acute and subacute noise stress conditions. Adult Wistar albino rats were exposed to acute noise stress and subacute noise stress and then the effect of ethanolic Costus speciosus rhizome extract on immunological parameters such as phagocytic index, avidity index, neutrophil adherence test and total leucocyte count were studied. Neutrophil adherence and total leukocyte counts were found decreased and the percentage of avidity and phagocytic index were significantly increased in the stressed group of rats. The result of statistical analysis showed that, the pre-treatment with Costus speciosus extract significantly altered favourably the levels of immunological parameters. Ethanolic extract of Costus speciosus rhizome have the potential to prevent noise stress induced changes in rodent immune system and has a strong immunomodulatory prospective applicable to clinical practices.
Estimation of total phenolic content and Studies on antioxidant activity of different extracts of Cadaba farinose Forsk by hydroxy radical and iron chelating techniques
Authors: Jambula DineshBabu  , Venugopalan Santhosh Kumar
Published: July 2020

Cadaba farinosa (family Capparidaceae) is generally known as “Indian cadaba” in the traditional ayurvedic system. The current study, aerial parts of different concentrates (Pet.ether, ethyl acetate and methanol) of Cadaba farinose was evaluated for its in-vitro antioxidant potential by hydroxy radical taking ascorbate as a standard. The iron-chelating activity is taking Ethylenediamine tetraacetate as standard and estimation of total phenol content as equivalent to mg/g of Gallic acid. The methanolic concentrates of Cadaba farinose & ascorbic acid exhibited antioxidant potential possessing IC50 205µg/ml & 65µg/ml (Hydroxy radical) , methanolic concentrates of Cadaba farinose & Ethylenediamine tetraacetate exhibited antioxidant potential possessing IC50 240µg/ml & 70µg/ml (iron-chelating activity). The methanolic and EA concentrates of Cadaba farinose contain total phenolic content 9.86 ± 0.62 and 3.98 ± 0.54, respectively. The IC50 value was originated that methanolic concentrates of Cadaba farinose more efficient in hydroxy radical, iron chelating activity compared EA & PE concentrates. The methanolic extract of Cadaba farinose having more free radical activity due to the presence of phenolic content as a bioactive compound. This result indicates that aerial parts of methanolic concentrate Cadaba farinose could serve as a natural antioxidant, which may be useful in preventing free radical-induced diseases.
Laparoscopic or open treatment for liver hydatid cyst? A single-institution experience: a prospective randomized control trial
Authors: Saad Ab-razq Mijbas  , Samer Makki Mohamed Al-Hakkak  , Ali Abood Alnajim  , Hassan Abdulla Abadi AL-Aquli
Published: July 2020

The gold standard modality of management of cystic echinococcosis remains surgery. Regardless of the increased interest in nonsurgical techniques. The study aims to compare laparoscopic versus open methods of the hydatid cyst of the liver regarding complication rate, postoperative hospital stays, and effectiveness. A prospective randomized study. One hundred two patients with liver hydatid cyst in which 60 patients fulfil study requirements. Those undergone either open surgical or laparoscopic approaches under cover of albendazole treatment. The data divided into two groups, group 1 (28), group2 (32), we collected demographic data, surgical approach types, and postoperative data. The overall of 102 patients with hydatid cyst of the liver was randomized,60 patients full the study requirements, 28 patients (46.67%) had a laparoscopic procedure, and 32 patients (53.33%) had an open method. The total number of liver hydatid cysts was 70, and the operative time means 77 min (range,60–120 min) in the laparoscopic group and 55 min (range, 40–110 min) in the open group which is significant (P-value 0.0267). The postoperative hospital stay means time was 32 hours (range, 1–3 days) in the group of the laparoscopic procedure and 52 hours (range,2– 5days) in the group of open type. The postoperative surgical complication was significantly less in the laparoscopic group than the open group (p-value 0.014). A Hydatid liver cyst can be managed either by open surgical or laparoscopic techniques with comparable results. Still, the laparoscopic approach is superior in less postoperative pain, hospital stay and time, but it is essential in choosing the suitable patients.
Jigsaw method as an effective co-operative learning method to understand biochemistry concepts for First year MBBS students
Authors: Krishna Veni D V  , Neetha Kundoor  , Radhakishan N
Published: July 2020

The jigsaw technique is a method of cooperative learning which makes the students depend and help each other in acquiring knowledge. This technique divides the class into groups to work on small problems with the purpose of collaborating into a final outcome. Jigsaw method is simple, comfortable to adopt and easy to implement. Jigsaw method facilitates active learning without traditional lecturing. It is a peer teaching method as an attempt to shift from a teacher to the learner-centred paradigm. The main aim of the study is to develop cooperative learning by using of Jigsaw technique among the 1 st year medical students for learning concepts of biochemistry. And to determine the effectiveness of the Jigsaw technique by post-assessment of their knowledge of biochemistry. A total of 100 medical students were recruited and their pre-knowledge on the concepts of biochemistry was assessed. The students were trained by using the Jigsaw technique and their post knowledge was assessed. In our present, around 28 students in the pretest scored below 60% marks and only 4 students in the post-test scored below 60%, indicating that there was a remarkable improvement in the scores of these students. And also 85 students scored above 80% marks. Jigsaw technique contribute to a better understanding of the concepts, facilitates active learning, problemsolving, improves analytical skills and logical thinking, enhances communication skills among students.
Sukarno and Colonialism: An Analysis of Indonesia’s Foreign Policy Discourse, 1955-1961
Authors: Yeremia Ardhitya Eduard
Published: July 2020

For the most part, the literature about Indonesia’s foreign policy does not stray far from a descriptive and chronological presentation of the subject. The fact of the matter is that an in-depth analysis of the nation’s foreign policy from a different era will impart valuable lessons to the current policymakers in charge of formulating and implementing such a policy. The era of Sukarno bore witness to the implementation of Indonesia’s foreign policy that was strong in ideas and practices. Employing discourse analysis, this article seeks to analyze five of Sukarno’s speeches, which were delivered in various international forums from 1955 to 1963. It demonstrates that during that time, Indonesia put forward a coherent and consistent foreign policy with colonialism as its master signifier. The promotion of such a discourse contributed positively to the diplomatic effort on the issue of West Papua by mobilizing supports from Asian-African nations, as well as attracting the interest of the superpowers. As a result, Indonesia’s national interest to bring West Papua into the Republic was well served, and furthermore, Indonesia succeeded in enhancing its image, role, and leadership in world affairs. This experience presents a challenge to the contemporary policymakers in producing a configuration of strong ideas and concepts that would allow the implementation of a foreign policy that serves the national interest, when the nation has once again risen as an important player on the world stage.
Perancangan dan Impelementasi Sistem Pengukuran Kepuasan Mahasiswa Terhadap Sarana Prasarana Kampus Universitas Dian Nuswantoro Berbasis Web
Authors: Rokhman Nur , Yanuarsari Dzuha Hening
Published: July 2020

Universitas Dian Nuswantoro Semarang merupakan universitas yang mempunyai akreditasi A sejak tahun 2017.  Hal ini menjadi tantangan sendiri sebagai upaya untuk mempertahan serta manjaga kualitas yang sudah diraih.  Salah satu yang menjadi faktor penting adalah pengawasan terhadap sarana dan prasarana yang sudah tersedia agar tetap memberikan pelayanan terbaik bagi mahasiswanya.  Salah satu usaha yang akan dapat dilaksanakan adalah pengukuran tingkat kepuasan mahasiswa terhadap sarana prasarana di Universitas Dian Nuswantoro Semarang.  Tujuan dari penelitian ini adalah bagaimana merancang  dan mengimplementasikan sebuah sistem berbasis web yang dapat mempermudah proses pengukuran tingkat kepuasan tersebut dimana dapat mengolah hasil survey secara otomatis dan realtime yang dalam bentuk grafik sehingga akan langsung dapat diketahui sarana prasarana mana yang mempunyai tingkat kepuasan terendah yang perlu diperbaiki di masa yang akan datang.  Hasil dari penelitian ini adalah menghasilkan aplikasi versi awal yang dapat menjadi input survey mahasiswa dan hasilnya surveynya akan disajikan dalam bentuk grafik yang akan menjadi masukan bagi Universitas Dian Nuswantoro Semarang untuk menjaga kualitas di masa yang akan datang