bluuebunny/crossref_metadata_2025 huggingface dataset:
Glomerular Proteinuria Predicts the Severity of Acute Kidney Injury in Puumala Hantavirus-Induced Tubulointerstitial Nephritis
Authors: Mantula Paula S. , Outinen Tuula K. , Clement Jan P.G. , Huhtala Heini S.A. , Pörsti Ilkka H. , Vaheri Antti , Mustonen Jukka T. , Mäkelä Satu M.
Published: March 2017

Background:Puumala virus (PUUV)-induced hemorrhagic fever with renal syndrome is common in many European countries. The typical renal histologic lesion is acute tubulointerstitial nephritis. We examined the type and kinetics of urine protein excretion and prognostic significance of proteinuria for the severity of acute kidney injury (AKI) in acute PUUV infection. Methods: The amount of dipstick albuminuria at hospital admission was analyzed in 205 patients with acute PUUV infection. Dipstick albuminuria at admission was graded into 3 categories: 0-1+, 2+, and 3+. In 70 patients, 24-h urinary excretion of protein, overnight urinary excretion of albumin, immunoglobulin (Ig) G, and α1-microglobulin also were measured over 3 consecutive days during the hospital stay. Results: Maximum median daily proteinuria, overnight albuminuria, and IgG excretion were observed over 5 days, while that of creatinine values was observed 9 days after the onset of the disease. The medians of maximum plasma creatinine levels during hospital stay were different in the 3 categories of dipstick albuminuria: 0-1+: 98 µmol/L (58-1,499), 2+: 139 µmol/L (71-829), and 3+: 363 µmol/L (51-1,285; p < 0.001). Dipstick albuminuria ≥2+ at admission could be detected in 89% of the patients who subsequently developed severe AKI. Glomerular proteinuria, but not tubular proteinuria (α1-microglobulin), correlated with the severity of the emerging AKI. Conclusion: In acute PUUV infection, maximum median proteinuria values preceded the most severe phase of AKI by a few days. A highly useful finding for clinical work was that a quick and simple albuminuria dipstick test at hospital admission predicted the severity of the upcoming AKI.
Rapid Regression of Obstructive Cardiac Rhabdomyoma in a Preterm Neonate after Sirolimus Therapy
Authors: Lee Seung Jae , Song Eun Song , Cho Hwa Jin , Choi Young Youn , Ma Jae Sook , Cho Young Kuk
Published: March 2017

Cardiac rhabdomyoma can be subclinical or fatal depending on the onset age, involving site, and the size and degree of invasion. Although most rhabdomyomas become smaller with time, emergency intervention is indicated when severe obstruction induces hemodynamic instability. Mammalian target of rapamycin (mTOR) inhibitors have been used to treat neonates and children with hemodynamically obstructive cardiac rhabdomyoma. Herein, we report a premature neonate at the gestational age of 30 + 4 weeks with severe left ventricular outflow tract obstructive cardiac rhabdomyoma who was successfully treated with the mTOR inhibitor sirolimus. To the best of our knowledge, this is the first recorded case of a premature neonate with obstructive cardiac rhabdomyoma who was successfully treated with an mTOR inhibitor. Therefore, sirolimus could be considered as an alternative medical option for managing premature neonates with obstructive cardiac rhabdomyoma.
A Case Report of Severe Delirium after Amantadine Withdrawal
Authors: Marxreiter Franz , Winkler Jürgen , Uhl Martin , Madžar Dominik
Published: March 2017

Amantadine is frequently used in addition to dopaminergic substances like dopamine agonists or L-Dopa in advanced Parkinson disease (PD). However, adverse effects like hallucinations limit its use. PD patients developing severe psychotic symptoms upon treatment with either dopaminergic substances and/or amantadine need to stop intake of any psychotropic substance. Here, we report the case of a 71-year-old PD patient without previously known cognitive impairment. He presented with drug-induced psychotic symptoms due to changes in his therapeutic regimen (increase in COMT inhibitors, newly introduced MAO B inhibitors). Also, amantadine had been part of his long-term medication for more than 2 years. The severity of his psychotic symptoms required a L-Dopa monotherapy. After changing his medication, the patient developed severe delirium that resolved rapidly after i.v. amantadine infusion, suggesting an amantadine withdrawal syndrome. Amantadine withdrawal syndrome is a rare adverse event that may present even in PD patients without cognitive impairment. This case report highlights the need for a gradual withdrawal of amantadine even if acute and severe psychotic symptoms are present. Moreover, this is the first report of a cognitively unimpaired patient developing an amantadine withdrawal syndrome.
Visual Loss from Choroidal Melanoma Mimicking Neurological Syndromes
Authors: Hammamji Karim , Reich Ehud , Arora Amit , Cohen Victoria M.L. , Sagoo Mandeep S.
Published: March 2017

Melanoma of the eye is rare, but can mimic a range of disorders. This report highlights 2 cases of choroidal melanoma with vision loss mimicking neurological diagnoses. The first patient is a 41-year-old white male with a known history of multiple sclerosis and a previous episode of optic neuritis in the right eye, who presented with a 6-month history of decreased vision in the same eye, and occasional photopsiae. He was treated with 2 courses of oral steroids for presumed recurrent optic neuritis. After a temporary improvement in his symptoms, his vision worsened, following which he had a head MRI, which revealed a solid intraocular mass. He was subsequently diagnosed with a choroidal melanoma for which he was treated successfully with ruthenium-106 plaque brachytherapy. The second patient is a 57-year-old female, who presented with a progressive cerebellar syndrome under investigation by the neurology service, as well as decreased vision in the right eye. Her visual acuity gradually deteriorated and her neurological assessment, which included a PET-CT, revealed uptake in the right eye. The diagnosis of a choroidal melanoma was made, and following conservative treatment with proton beam radiotherapy, she had an enucleation of the eye. Intraocular tumours can masquerade as many different entities. Unexplained unilateral visual loss, especially if it is atypical for a neurological syndrome, should prompt dilated fundoscopy and referral to an ophthalmologist.
Dual- versus Single-Energy CT-Angiography Imaging for Patients Undergoing Intracranial Aneurysm Repair
Authors: Abdulazim Amr , Rubbert Christian , Reichelt Dorothea , Mathys Christian , Turowski Bernd , Steiger Hans-Jakob , Hänggi Daniel , Etminan Nima
Published: March 2017

Background: The invasiveness and risk of thromboembolic complications of catheter angiography underline the need for alternative imaging modalities in patients following intracranial aneurysm (IA) repair. However, the overall image quality of existing noninvasive imaging modalities, such as single-energy CT angiography (SE-CTA), compromises its value in this respect. Objective: We prospectively investigated the value of a novel dual-energy CTA (DE-CTA) scanner and algorithm for assessing the degree of occlusion and parent vessel patency in patients following IA repair. Methods: A prospective cohort of 17 patients underwent DE-CTA imaging following surgical or endovascular IA repair. This dataset was matched with an identical historical cohort of 17 patients, who underwent IA repair and SE-CTA imaging. Beam-hardening artifacts, as a measure for objective imaging quality were analyzed based on the volume of a prolate ellipsoid, whereas subjective imaging quality at the IA site and corresponding parent vessels was rated by 2 independent neuroradiologists on a scale from 4 (excellent, no artifacts) to 1 (poor, severe artifacts). Results: Objective DE-CTA image quality was markedly higher, compared to SE-CTA in patients undergoing surgical (0.77 ± 0.23 vs. 10.91 ± 1.88 mL, respectively; p < 0.001) or endovascular (32.36 ± 10.62 vs. 107.63 ± 24.51 mL, respectively; p = 0.026) IA repair. Subjective image quality for DE-CTA was significantly improved compared to SE-CTA in the surgical group but not in the endovascular group. The calculated dose values for DE-CTA in our study remain markedly below the legally required radiation dose limits. Conclusion: The imaging quality of DE-CTA, especially for patients undergoing surgical IA repair, is distinctly superior, compared to SE-CTA imaging. Therefore, DE-CTA may serve as a noninvasive alternative for assessing the IA occlusion rate and parent vessel patency.
The motivation for learning German at a Center for Language Studies (CLS)
Authors: Canato Juliana Bonsi Corrêa , Rozenfeld Cibele Cecílio de Faria
Published: March 2017

The student´s motivation is identified as central to a satisfactory learning process and, for this reason, many teachers are constantly engaged in improving their practices. In this work we aim to shed light on a multiliteracies project, which involved the production of a video clip and aimed to increase motivation of German students in a Language Study Center at a public school in the State of São Paulo. To support our reflections, we sought theoretical support primarily on the concepts of motivation (DÖRNYEI 1994, 2001, 2014; VALLERAND 1997 and others) and multiliteracies (ROJO 2012, 2013). The research, of a qualitative nature, was developed from data collected with secondary and high school students in a Language Study Centre in the State of São Paulo during 2015. The results show the great impact of multiliteracies projects in student´s motivation
Bosnian Muslims and the Idea of a “European Islam” in Post-War Sarajevo
Authors: Jevtić Jana
Published: March 2017

This is an ethnographic study of religious experience in post-war Sarajevo. It argues that, against the backdrop of the shifting configurations of social powers that affect nation-state institutions along with intergenerational change and class, the locus of ostensibly “real” Bosnian Islam—European and tolerant—and the identity of those who speak on its behalf have been rethought and reformed. Taking the Boycott, Divestment and Sanctions (bds) campaign as its ethnographic entry point, this article examines the variety of Muslim voices that shape the current facets of Bosnian Islam and its position in the complex relations between Europe and Islam.
Paepalanthus altamirensis, a new species of Paepalanthus subg. Platycaulon (Eriocaulaceae) from Brazil
Authors: TISSOT-SQUALLI MARA L. , SAUTHIER LUANA J.
Published: March 2017

We describe Paepalanthus altamirensis, a new species of Paepalanthus subg. Platycaulon, compare it with other species of the subgenus, and discuss its morphological variation, habitat, and conservation. Paepalanthus altamirensis has red coloration on the adaxial surface of the foliar base, like six other species of the subgenus, but can be easily differentiated by morphological and anatomical features of vegetative and reproductive organs. Paepalanthus altamirensis has a restricted distribution and few mature individuals are known, therefore the species is classified as critically endangered according to the criteria of IUCN.
Geographical and bathymetric distribution of mysids (Crustacea: Mysida)
in the seas of the Iberian Peninsula
Authors: VICENTE CARLOS SAN
Published: March 2017

The zoogeographic distribution of mysid species occurring in the diverse seas of the Iberian Peninsula and neighbouring areas is analysed. For each species, bathymetric range and localities data are reported. A total of 129 mysid species belonging to 50 genera have been recorded, representing 11% of all known world extant species and the 28% of genera. Littoral mysids are the most diverse group (64 species) followed by the outer-self to upper-bathyal slope with 54 known species. Patterns of bathymetric zonation are characterized by four bathymetric discontinuities at about 100, 500, 1300 and 2700 m. Each geographical region is characterized by the presence of a mixture of exclusive and shared species composition. Mysid distributions suggest that an important grouping of species present in the Iberian fauna share a common origin. Based on the analysis of published records and reported species, it is suggested that there is a high probability of the discovery of new species of Mysida in the water surrounding the Iberian Peninsula.
A new Aceria species (Acari: Eriophyidae) from Spain on Pycnocomon rutifolium (Dipsacaceae) and supplementary descriptions of Aceria eucricotes and A. kuko from Lycium spp. (Solanaceae)
Authors: RIPKA GÉZA , SÁNCHEZ IŇIGO
Published: March 2017

A new species of eriophyoid mite, Aceria pycnocomi sp. nov., associated with Pycnocomon rutifolium (Dipsacaceae), is described and illustrated from Spain. Morphological differences distinguishing this new species from similar Aceria species are discussed. The female, male and nymph of Aceria eucricotes (Nalepa, 1892) and Aceria kuko (Kishida, 1927) are redescribed and illustrated from Spain and Hungary, respectively; both were collected from Lycium spp. (Solanaceae). Morphological differences distinguishing these two species are discussed.
Laubuka parafasciata, a new cyprinid fish species (Teleostei: Cyprinidae) from Mizoram northeastern India
Authors: LALRAMLIANA LALRAMLIANA , VANLALHLIMPUIA DENIS , SINGH MAHENDER
Published: March 2017

Laubuka parafasciata, new species, is described from the Sala River of Mizoram, northeast India. The species differs markedly from all its congeners, with the exception of L. fasciata, in having a broad, dark-brown, midlateral stripe from the posterior rim of the orbit to the middle of the caudal-fin base. It is further distinguished from all other species in the genus by the combination of the following characters: premaxillae not in contact at symphysis, 16 precaudal vertebrae, minute tubercles scattered on the lower jaw, 28–33 lateral-line scales, 16–18 predorsal scales, 8½ branched dorsal-fin rays, 2½ scales between lateral line and pelvic-fin origin, and 16½–19½ branched anal-fin rays.
Taxonomic description and 3D modelling of a new species of myzostomid (Annelida, Myzostomida) associated with black corals from Madagascar
Authors: TERRANA LUCAS , EECKHAUT IGOR
Published: March 2017

Eenymeenymyzostoma nigrocorallium n. sp. is the first species of myzostomid worm associated with black corals to be described. Endoparasitic specimens of E. nigrocorallium were found associated with three species of antipatharians on the Great Reef of Toliara. Individuals inhabit the gastrovascular ducts of their hosts and evidence of infestation is, most of the time, not visible externally. Phylogenetic analyses based on 18S rDNA, 16S rDNA and COI data indicate a close relation to Eenymeenymyzostoma cirripedium, the only other species of the genus. The morphology of E. nigrocorallium is very unusual compared to that of the more conventional E. cirripedium. The new species has five pairs of extremely reduced parapodia located on the body margin and no introvert, cirri or lateral organs. Individuals are hermaphroditic, with the male and female gonads both being located dorsally in the trunk. It also has a highly developed parenchymo-muscular layer on the ventral side, and the digestive system lies in the middle part of the trunk. A three-dimensional digital model of this worm’s body plan has been constructed whereby the external morphology and in toto views of the observed organ systems (nervous, digestive and reproductive) can be viewed on-screen: http://doi.org/10.13140/RG.2.2.17911.21923.
The Science of William M. Gray: His Contributions to the Knowledge of Tropical Meteorology and Tropical Cyclones
Authors: Klotzbach Philip J. , Chan Johnny C. L. , Fitzpatrick Patrick J. , Frank William M. , Landsea Christopher W. , McBride John L.
Published: March 2017

Advances in knowledge in tropical meteorological research are discussed in the context of contributions made by Professor William M. Gray. Gray pioneered the compositing approach to observational tropical meteorology through assembling of global radiosonde datasets and tropical cyclone research flight data. In the 1970s, he made fundamental contributions to knowledge of convective–larger-scale interactions. Throughout his career, he wrote seminal papers on tropical cyclone structure, cyclogenesis, motion, and seasonal forecasts. His conceptual development of a seasonal genesis parameter also laid an important framework for both seasonal forecasting as well as climate change studies on tropical cyclones. His work was a blend of both observationally based studies and the development of theoretical concepts. This paper reviews the progress in knowledge in the areas where Dr. Gray provided his largest contributions and describes the scientific legacy of Gray’s contributions to tropical meteorology.
A New Method to Correct Radiosonde Temperature Biases Using Radio Occultation Data
Authors: Tradowsky Jordis S. , Burrows Chris P. , Healy Sean B. , Eyre John R.
Published: March 2017

A new method to estimate radiosonde temperature biases using radio occultation measurements as a reference has been developed. The bias is estimated as the difference between mean radio occultation and mean radiosonde departures from collocated profiles extracted from the Met Office global numerical weather prediction (NWP) system. Using NWP background profiles reduces the impact of spatial and temporal collocation errors. The use of NWP output also permits determination of the lowest level at which the atmosphere is sufficiently dry to analyze radio occultation dry temperature retrievals. The authors demonstrate the advantages of using a new tangent linear version of the dry temperature retrieval algorithm to propagate bending angle departures to dry temperature departures. This reduces the influence of a priori assumptions compared to a nonlinear retrieval. Radiosonde temperature biases, which depend on altitude and the solar elevation angle, are presented for five carefully chosen upper-air sites and show strong intersite differences, with biases exceeding 2 K at one of the sites. If implemented in NWP models to correct radiosonde temperature biases prior to assimilation, this method could aid the need for consistent anchor measurements in the assimilation system. The method presented here is therefore relevant to NWP centers, and the results will be of interest to the radiosonde community by providing site-specific temperature bias profiles. The new tangent linear version of the linear Abel transform and the hydrostatic integration are described in the interests of the radio occultation community.
Climatology of Size, Shape, and Intensity of Precipitation Features over Great Britain and Ireland
Authors: Fairman Jonathan G. , Schultz David M. , Kirshbaum Daniel J. , Gray Suzanne L. , Barrett Andrew I.
Published: March 2017

A climatology of precipitation features (or objects) from the Great Britain and Ireland radar-derived precipitation mosaic from 2006 to 2015 is constructed, with features defined as contiguous areas of nonzero precipitation rates. Over the 10 years, there are 54 811 747 nonunique precipitating features over 100 km2 in area, with a median precipitation feature area of 249 km2, median major axis length of 29.2 km, median aspect ratio of 2.0:1, median feature mean precipitation rate of 0.49 mm h−1, and median feature maximum precipitation rate of 2.4 mm h−1. Small-scale precipitating systems are most common, but larger systems exceeding 10 000 km2 contribute close to 70% of the annual precipitation across the study region. Precipitation feature characteristics are sensitive to changes in annual and diurnal environment, with feature intensities peaking during the afternoon in summer and the largest precipitation features occurring during winter. Precipitation intensities less than 5 mm h−1 comprise 97.3% of all precipitation occurrences and contribute 83.6% of the total precipitation over land. Banded precipitation features (defined as precipitation features with aspect ratio at least 3:1 and major axis length at least 100 km) comprise 3% of all precipitation features by occurrence, but contribute 23.7% of the total precipitation. Mesoscale banded features (defined as banded precipitation features with major axis length at least 100 km and total area not exceeding 10 000 km2) and mesoscale convective banded features (defined as banded precipitation features with at least 100 km2 of precipitation rates exceeding 10 mm h−1) are most prevalent in southwestern England, with mesoscale convective banded features contributing up to 2% of precipitation.
Ensemble Probabilistic Prediction of a Mesoscale Convective System and Associated Polarimetric Radar Variables Using Single-Moment and Double-Moment Microphysics Schemes and EnKF Radar Data Assimilation
Authors: Putnam Bryan J. , Xue Ming , Jung Youngsun , Snook Nathan A. , Zhang Guifu
Published: March 2017

Ensemble-based probabilistic forecasts are performed for a mesoscale convective system (MCS) that occurred over Oklahoma on 8–9 May 2007, initialized from ensemble Kalman filter analyses using multinetwork radar data and different microphysics schemes. Two experiments are conducted, using either a single-moment or double-moment microphysics scheme during the 1-h-long assimilation period and in subsequent 3-h ensemble forecasts. Qualitative and quantitative verifications are performed on the ensemble forecasts, including probabilistic skill scores. The predicted dual-polarization (dual-pol) radar variables and their probabilistic forecasts are also evaluated against available dual-pol radar observations, and discussed in relation to predicted microphysical states and structures.

Evaluation of predicted reflectivity (Z) fields shows that the double-moment ensemble predicts the precipitation coverage of the leading convective line and stratiform precipitation regions of the MCS with higher probabilities throughout the forecast period compared to the single-moment ensemble. In terms of the simulated differential reflectivity (ZDR) and specific differential phase (KDP) fields, the double-moment ensemble compares more realistically to the observations and better distinguishes the stratiform and convective precipitation regions. The ZDR from individual ensemble members indicates better raindrop size sorting along the leading convective line in the double-moment ensemble. Various commonly used ensemble forecast verification methods are examined for the prediction of dual-pol variables. The results demonstrate the challenges associated with verifying predicted dual-pol fields that can vary significantly in value over small distances. Several microphysics biases are noted with the help of simulated dual-pol variables, such as substantial overprediction of KDP values in the single-moment ensemble.
Sustainable Climate Change Adaptation in Indian Country
Authors: McNeeley Shannon M.
Published: March 2017

Much of the academic literature and policy discussions about sustainable development and climate change adaptation focus on poor and developing nations, yet many tribal communities inside the United States include marginalized peoples and developing nations who face structural barriers to effectively adapt to climate change. There is a need to critically examine diverse climate change risks for indigenous peoples in the United States and the many structural barriers that limit their ability to adapt to climate change. This paper uses a sustainable climate adaptation framework to outline the context and the relationships of power and authority, along with different ways of knowing and meaning, to illustrate the underpinnings of some tribes’ barriers to sustainable climate adaptation. The background of those structural barriers for tribes is traced, and then the case of water rights and management at the Wind River Reservation in Wyoming is used to illustrate the interplay of policy, culture, climate, justice, and limits to adaptation. Included is a discussion about how the rulings of the Big Horn general stream adjudication have hindered tribal climate change adaptation by limiting the quantity of tribal reserved water rights, tying those rights to the sole purposes of agriculture, which undermines social and cultural connections to the land and water, and failing to recognizing tribal rights to groundwater. Future climate projections suggest increasing temperatures, and changes in the amount and timing of snowpack, along with receding glaciers, all of which impact water availability downstream. Therefore, building capacity to take control of land and water resources and preparing for climate change and drought at Wind River Reservation is of critical importance.
Positive IgM in Congenital CMV Infection
Authors: Bilavsky Efraim , Watad Salmas , Levy Itzhak , Linder Nehama , Pardo Joseph , Ben-Zvi Haim , Attias Joseph , Amir Jacob
Published: March 2017

Neonatal serum detection of cytomegalovirus (CMV) immunoglobulin M (IgM) has low sensitivity in identifying congenital cytomegalovirus (cCMV). Several reports have endeavored to associate the presence/absence of IgM to disease severity. Data were collected for all infants with cCMV followed in our clinic. Infant outcome after birth was compared between infants who tested positive or negative. Sensitivity of positive IgM in diagnosing cCMV was 40.7%. The rate of symptomatic disease in those who tested positive was statistically higher (67.7%, P < .001). Odds ratio for symptomatic disease in infants with positive IgM born after a maternal primary infection was 3.47 (95% confidence interval = 1.7-7.1). Positive IgM was found in only 48.8% of symptomatic and 22.1% of asymptomatic children. Our results demonstrated a low sensitivity of IgM in diagnosing cCMV. However, while a positive IgM antibody for CMV is associated with a more symptomatic disease, it does not serve as a precise laboratory marker for a severity.
The effects of a community mental health intervention project upon family caregivers of persons with suspected mental illness in the Chinese cultural context
Authors: Ng Petrus , Young Daniel KW , Pan Jiayan , Law King-Keung
Published: March 2017

Family members play an important role in caregiving with more emphasis on early intervention for people suffering from mental illness. Using both quantitative and qualitative methods, this study examines the effects of a community mental health intervention project (CoMHIP) on burdens of caregivers who have family members with suspected mental illness. Results showed that family caregivers’ burden and psychological stress level had been reduced ( p < .001). The caregivers subjectively experienced a significant reduction in stress regarding the caregiving subscales, supervision, tension, worrying and urging after seeking CoMHIP service. Findings for the study have implications on social work interventions regarding family caregiving of people with suspected mental health problems.
Consumer participation at Specialist Homelessness Services: Do the homeless have a say in the services they receive?
Authors: Phillips Darren , Kuyini Ahmed Bawa
Published: March 2017

This study in the state of New South Wales, Australia, explored what Specialist Homelessness Services are currently implementing in regard to consumer participation, what is working and what barriers to consumer participation have been encountered by both service users and providers. Three staff members, one consumer volunteer and 10 homeless persons from three services were interviewed. The interviews were analysed using thematic analysis. The study found that while consumers have some opportunities to participate, and that participation is beneficial, there were barriers to participation, such as staff attitudes and the nature of the consumer group. The implications of these findings for staff, consumers and future policy direction are discussed.
Motivation for Ethno-Cultural Continuity as a Predictor of Acculturation and Adaptation in Two Generations of Latvian Russians
Authors: Ryabichenko Tatiana , Lebedeva Nadezhda
Published: March 2017

This article presents the results of empirical research on the relationship of motivation for ethno-cultural continuity (MEC) and strategies of acculturation among two generations of the Russian minority in Latvia. We sampled 107 Russian families (mothers: N = 107, age = 35-59, M = 42 years; late adolescents and youth: N = 107, age = 16-24, M = 17 years). The questionnaire included measures of motivation for ethno-cultural continuity, acculturation strategies, sociocultural adaptation, and self-esteem. A path model showed that motivation for ethno-cultural continuity, preference for assimilation, self-esteem, and sociocultural adaptation of mothers significantly related to those of their children. A motivation for ethno-cultural continuity of mothers predicted their preference for integration and self-esteem, while a motivation for ethno-cultural continuity of adolescents predicted their preference for separation. Preference for integration promoted better sociocultural adaptation and self-esteem in both generations. The results allowed consideration of the process of acculturation on the three interrelated levels: individual, family, and ethnic group, with the central role of the family, teaching younger generations to maintain heritage culture and successfully integrate in the larger society.
Models of Caries Formation around Dental Composite Restorations
Authors: Ferracane J.L.
Published: March 2017

The main reason cited for the replacement of dental composite restorations is the recurrence of caries. Numerous models—both in vitro, with acid gels or bacterial biofilms, and in situ, with dental appliances—have been used to study caries formation around dental composites. The literature shows that many factors may affect caries formation, including marginal gap formation, gap size, the local chemical environment, the durability of the bonded interface, the extent of bacterial penetration, and the presence of mechanical loading. Studies have also shown that what have been called wall lesions may form independent of surface lesions, though not likely due to microleakage through very small gap spaces in the clinical situation. Gap size and mechanical loading have been shown to be related to lesion severity within in vitro models, but these results do not correspond exactly with those obtained from in situ studies using restorations in dental appliances. Though not conclusive, some in vitro models have shown that certain materials possessing antimicrobial characteristics may reduce the severity of lesion formation, suggesting possible pathways for developing new composite and adhesive materials for restorations with potentially enhanced longevity.
New Standards Require Teaching More Statistics
Authors: Lovett Jennifer N. , Lee Hollylynne S.
Published: March 2017

Mathematics teacher education programs often need to respond to changing expectations and standards for K-12 curriculum and accreditation. New standards for high school mathematics in the United States include a strong emphasis in statistics. This article reports results from a mixed methods cross-institutional study examining the preparedness of preservice secondary mathematics teachers to teach statistics and identifying factors and experiences that influence their preparedness. Our results suggest that the cohort of teachers entering secondary mathematics classrooms in 2015-2016 were not well prepared to teach statistics. Specific suggestions are given for how teacher education programs must rise to the challenge of preparing their graduates to teach statistics.
Differential Aging in Place and Depressive Symptoms: Interplay Among Time, Income, and Senior Housing
Authors: Park Sojung , Kim BoRin , Han Yoonsun
Published: March 2017

Objective:

We examined cumulative and differential experiences of aging in place.

Method:

Data came from the 2002 and 2010 wave of the Health Retirement Study. We modeled the trajectory of later-life depressive symptoms, and how senior-housing environments moderate the negative association between economic disadvantages and depressive symptoms.

Results:

At baseline, economically disadvantaged older adults were more likely to exhibit depressive symptoms. However, detrimental effects of income group (non-low income vs. moderate income; non-low income vs. low income) on depressive symptoms did not significantly change over time. The age-leveler hypothesis may account for nonsignificant effects of disadvantaged income groups over time.

Discussion:

Findings suggest that moderate-income seniors may experience positive differentials if they age in place in a supportive senior-housing environment. Moderate-income seniors may have broader opportunities in senior housing compared to private-home peers. Senior housing might partially counter risks such as low mental health, emerging from life-course disadvantage.
Home, domestic work and the state: The spatial politics of domestic workers’ activism
Authors: England Kim
Published: March 2017

This article explores the spatialities associated with the recent emergence of a social movement of domestic workers in the United States. Domestic work is rendered invisible, not only as a form of ‘real work’, but also because it is hidden in other people’s homes. The article unpacks the home as a private space beyond government intervention, and as domestic worker activists argue, when homes are workplaces workers should be protected from exploitation. Domestic workers have become active and visible in campaigns to gain coverage under labour legislation at the state and federal government levels. An analysis of the success of their campaigns reveals a set of strategies and tactics that draw on feminist care ethics in a range of different locations, and that thinking spatially has been pivotal in the emergence and continued growth of their social movement.
Dual task training in persons with Multiple Sclerosis: a feasability randomized controlled trial
Authors: Sosnoff Jacob J , Wajda Douglas A , Sandroff Brian M , Roeing Kathleen L , Sung JongHun , Motl Robert W
Published: March 2017

Objective:

To determine the feasibility of dual task training in persons with Multiple Sclerosis.

Design:

Randomized, single-blinded controlled trial.

Setting:

University research laboratory.

Participants:

A total of 234 individuals inquired about the investigation. After screening, 20 individuals with multiple sclerosis who self-reported problems with multitasking and were ambulatory volunteered for the investigation. 14 participants completed the post-assessment following the 12-week intervention.

Intervention:

Participants were randomly assigned to either single task training program which focused on balance and walking function ( n=6) or dual task training program that incorporated cognitive tasks in balance and walking training ( n=8).

Measures:

Before and after the 12-week interventions participants underwent assessments of walking; dual task walking; balance (Berg Balance Scale and balance confidence) and cognition as indexed by the Brief International Cognitive Assessment for MS.

Results:

There was an 8.5% recruitment rate, a 70% retention rate, and a 100% adherence rate. There was a trend for dual task gait speed to improve in the dual task training group following the intervention (Pre: task 1: 109.8±39, task 2: 104.2±34.1; Post: task 1:127.6±40.1, task 2: 122.8±37.4; P=0.14; η2 = 0.24). There was also a trend for the dual task training group (28.1) to have greater performance than the control group (24.7) on visuospatial memory ( P=0.10; η2= 0.23). There were no changes in cognitive performance during walking trials.

Conclusions:

The study procedures were found to be feasible and improvements should be made in recruitment efforts going forward. Further examination of dual task training programs in individuals with multiple sclerosis is warranted.
Dementia incidence and predictors in cerebral amyloid angiopathy patients without intracerebral hemorrhage
Authors: Xiong Li , Boulouis Gregoire , Charidimou Andreas , Roongpiboonsopit Duangnapa , Jessel Michael J , Pasi Marco , Reijmer Yael D , Fotiadis Panagiotis , Ayres Alison , Merrill Emily , Schwab Kristin , Blacker Deborah , Gurol M Edip , Greenberg Steven M , Viswanathan Anand
Published: March 2017

Cerebral amyloid angiopathy (CAA) is a common cause of cognitive impairment in older individuals. This study aimed to investigate predictors of dementia in CAA patients without intracerebral hemorrhage (ICH). A total of 158 non-demented patients from the Stroke Service or the Memory Clinic who met the modified Boston Criteria for probable CAA were included. At baseline, neuroimaging markers, including lobar microbleeds (cerebral microbleeds (CMBs)), white matter hyperintensities (WMH), cortical superficial siderosis (cSS), magnetic resonance imaging (MRI)-visible centrum semiovale perivascular spaces (CSO-PVS), lacunes, and medial temporal atrophy (MTA) were assessed. The overall burden of small vessel disease (SVD) for CAA was calculated by a cumulative score based on CMB number, WMH severity, cSS presence and extent and CSO-PVS severity. The estimated cumulative dementia incidence at 1 year was 14% (95% confidence interval (CI): 5%–23%), and 5 years 73% (95% CI: 55%, 84%). Age (hazard ratio (HR) 1.05 per year, 95% CI: 1.01–1.08, p = 0.007), presence of MCI status (HR 3.40, 95% CI: 1.97–6.92, p < 0.001), MTA (HR 1.71 per point, 95% CI: 1.26–2.32, p = 0.001), and SVD score (HR 1.23 per point, 95% CI: 1.20–1.48, p = 0.030) at baseline were independent predictors for dementia conversion in these patients. Cognitive deterioration of CAA patients appears attributable to cumulative changes, from both vasculopathic and neurodegenerative lesions.
Evaluation of the Risk Factors for a Rotator Cuff Retear After Repair Surgery
Authors: Lee Yeong Seok , Jeong Jeung Yeol , Park Chan-Deok , Kang Seung Gyoon , Yoo Jae Chul
Published: March 2017

Background:

A retear is a significant clinical problem after rotator cuff repair. However, no study has evaluated the retear rate with regard to the extent of footprint coverage.

Purpose:

To evaluate the preoperative and intraoperative factors for a retear after rotator cuff repair, and to confirm the relationship with the extent of footprint coverage.

Study Design:

Cohort study; Level of evidence, 3.

Methods:

Data were retrospectively collected from 693 patients who underwent arthroscopic rotator cuff repair between January 2006 and December 2014. All repairs were classified into 4 types of completeness of repair according to the amount of footprint coverage at the end of surgery. All patients underwent magnetic resonance imaging (MRI) after a mean postoperative duration of 5.4 months. Preoperative demographic data, functional scores, range of motion, and global fatty degeneration on preoperative MRI and intraoperative variables including the tear size, completeness of rotator cuff repair, concomitant subscapularis repair, number of suture anchors used, repair technique (single-row or transosseous-equivalent double-row repair), and surgical duration were evaluated. Furthermore, the factors associated with failure using the single-row technique and transosseous-equivalent double-row technique were analyzed separately.

Results:

The retear rate was 7.22%. Univariate analysis revealed that rotator cuff retears were affected by age; the presence of inflammatory arthritis; the completeness of rotator cuff repair; the initial tear size; the number of suture anchors; mean operative time; functional visual analog scale scores; Simple Shoulder Test findings; American Shoulder and Elbow Surgeons scores; and fatty degeneration of the supraspinatus, infraspinatus, and subscapularis. Multivariate logistic regression analysis revealed patient age, initial tear size, and fatty degeneration of the supraspinatus as independent risk factors for a rotator cuff retear. Multivariate logistic regression analysis of the single-row group revealed patient age and fatty degeneration of the supraspinatus as independent risk factors for a rotator cuff retear. Multivariate logistic regression analysis of the transosseous-equivalent double-row group revealed a frozen shoulder as an independent risk factor for a rotator cuff retear.

Conclusion:

Our results suggest that patient age, initial tear size, and fatty degeneration of the supraspinatus are independent risk factors for a rotator cuff retear, whereas the completeness of rotator cuff repair based on the extent of footprint coverage and repair technique are not.
Development of Adolescent Moral and Civic Identity Through Community Service: A Qualitative Study in Hong Kong
Authors: Xu Huixuan , Yang Min
Published: March 2017

This article draws on Marcia’s model that defines four statuses of adolescents’ identity formation to examine adolescent moral and civic identity formation. Interviews were conducted with 23 students at three Hong Kong senior secondary schools to address the following research question: How does community service help adolescents develop their moral and civic identities? Among the participants, most of them reported attaining moral identity development and just a few participants reported civic identity development; nonetheless, one of them did not report identity development in the moral and civic domains. Furthermore, five core elements of community service programs facilitating the participants’ identity formation emerged from the findings, namely, meaningful service activities, diversity, youth voice, reflection, and extended service duration. The influence of these service elements varied across the moral and civic domains of identity. By reporting the findings gained from an East Asian school setting, the article contributes to a fuller understanding of the role of community service in adolescent identity formation.
Differential and Quantitative Analyses of mRNA Expression of Glucosyltransferases from Streptococcus mutans MT8148
Authors: Fujiwara T. , Hoshino T. , Ooshima T. , Hamada S.
Published: March 2017

Streptococcus mutans produces three glucosyltransferases, coded by gtfB, gtfC, and gtfD, whose cooperative action is essential for sucrose-dependent cellular adhesion. This cellular adhesion plays an important role in the formation of dental plaque and the initiation of dental caries. Since they bear genetic similarities and are large in size, differentiation of their gene expression has been difficult, and little is known about the dynamic process of gtf expression. Using a real-time reverse-transcription/polymerase chain-reaction, we determined the expression of each gtf. Under various conditions, the relative levels of transcription were gtfB > gtfD > gtfC. Sucrose enhanced gtfD expression, whereas it reduced that of gtfB and gtfC, suggesting the presence of independent promoters. Quantitative analyses demonstrated coincidence between the ratio of expression of each gtf and the ratio previously identified as optimal for sucrose-dependent adhesion in vitro, suggesting that S. mutans produces GTF at an optimal ratio to adhere to the tooth surface.
Contraction Stress Related to Degree of Conversion and Reaction Kinetics
Authors: Braga R.R. , Ferracane J.L.
Published: March 2017

Polymerization shrinkage of composites bonded to cavity preparations generates stress on the tooth/restoration interface. The purpose of this study was to verify the influence of degree of conversion and speed of polymerization reaction on contraction stress. We prepared experimental composites with different curing rates by varying the concentration of inhibitor (butylated hydroxytoluene). We verified the effect of degree of conversion by submitting one of the composites to different photo-activation times. Contraction stress was monitored for 10 minutes in a tensilometer. Fourier-transformed infrared spectrometry was used for assessment of the degree of conversion. Volumetric shrinkage was determined by means of a mercury dilatometer. Degree of conversion and volumetric shrinkage showed a non-linear relationship with energy density. Degree of conversion showed a pronounced influence on stress. Increased inhibitor concentration reduced curing rate and contraction stress in composites, without compromising the final degree of conversion.
Immunohistochemical Detection of Salivary Agglutinin/gp-340 in Human Parotid, Submandibular, and Labial Salivary Glands
Authors: Bikker F.J. , Ligtenberg A.J.M. , van der Wal J.E. , van den Keijbus P.A.M. , Holmskov U. , Veerman E.C.I. , Nieuw Amerongen A.V.
Published: March 2017

Salivary agglutinin is a Streptococcus mutans binding protein and a member of the scavenger receptor cysteine-rich superfamily. It is identical to lung gp-340 and brain DMBT1, which possibly play a role in innate immunity and tumor suppression, respectively. The goal of this study was to localize salivary agglutinin in human salivary glands. Two monoclonal antibodies, directed against gp-340, were characterized. mAb 213-1 reacted with sialic acid epitopes and cross-reacted with MUC7. The reaction with mAb 213-6 disappeared after reduction, suggesting that a protein epitope was recognized. In the parotid gland, immunohistochemical labeling with mAb 213-6 was found in the duct cells. In the submandibular gland and labial gland, both serous acini and demilune cells were labeled. In the labial gland, labeling was found at the luminal side of the duct cells. Salivary agglutinin was distinctly localized in salivary glands, but in distinct glandular secretions, no differences in electrophoretic behavior were observed.
The Association between Generalized Joint Hypermobility and Temporomandibular Joint Disorders: A Systematic Review
Authors: Dijkstra P.U. , Kropmans T.J.B. , Stegenga B.
Published: March 2017

To analyze conflicting evidence in the literature for the association between temporomandibular joint disorders (TMD) and generalized joint hypermobility (GJH), we performed a bibliographic search. The methodological quality of the 14 papers found was assessed according to 14 criteria. Papers were included in the analysis if the study population was clinically relevant, if range of motion of 2 or more joints was assessed on the left and right sides, and if cases had a TMD. Four studies fulfilled these selection criteria. Data from 3 studies, 113 cases and 95 controls, were available for analysis. Twenty-six cases and five controls were hypermobile (odds ratio, 5.4). In a sensitivity analysis, the odds ratio changed from significant to non-significant in 2 of 5 scenarios. As a result, it is not clear whether GJH is associated with TMD, and more rigorous studies are needed.
β-Galactosidase Activity in Saliva is Associated with Oral Malodor
Authors: Sterer N. , Bar-Ness Greenstein R. , Rosenberg M.
Published: March 2017

Deglycosylation of oral mucins may be a critical initial step leading to their subsequent proteolysis and putrefaction. The present study was undertaken to determine whether activity in saliva of a major glycosidic enzyme (β–galactosidase) is associated with oral malodor in a group of 64 subjects. Enzyme activity was detected by the use of a chromogenic substrate (X-Gal) impregnated on paper discs. Malodor-related measurements included two odor judges' assessments of whole-mouth and tongue malodor, and volatile sulfide levels measured by a portable sulfide monitor (Interscan Corp.). β–galactosidase assay scores were significantly associated with both odor judges' scores for whole-mouth (p ≤ 0.002; Spearman) and tongue malodor (p ≤ 0.001; Spearman). β–galactosidase activity and sulfide monitor measurements both factored significantly into multiple regression equations for odor judge scores, yielding multiple r-values ranging from 0.47 (p = 0.0007) to 0.60 (p < 0.0001). Analysis of the data presented indicates that β–galactosidase activity in saliva is correlated with oral malodor.