bluuebunny/crossref_metadata_2025 huggingface dataset:
Klüver Bucy syndrome following hypoglycaemic coma in a patient with glycogen storage disease type Ib
Authors: Boudjemline Alix Mollet , Isapof Arnaud , Witas Jean‐Bernard , Petit François M. , Gajdos Vincent , Labrune Philippe
Published: November 2010

Patients with type I glycogen storage disease (GSD) have poor tolerance to fasting, sometimes less than 3 hours during infancy. Even though most patients are able, as they get older, to tolerate a longer fasting period, they are at permanent risk for fast‐induced hypoglycaemia, even in adulthood. Klüver Bucy syndrome, is characterized by psychic blindness (inability to recognize familiar objects), hypermetamorphosis (strong tendency to react to visual stimulus), increased oral exploration, placidity, indiscriminate hyper‐sexuality and change in dietary habits. In this case report, we describe the development of Klüver Bucy syndrome in a 28‐year‐old man with type Ib GSD, following prolonged and severe hypoglycaemia triggered by a common respiratory infection.
Urgent metabolic service improves survival in long‐chain 3‐hydroxyacyl‐CoA dehydrogenase (LCHAD) deficiency detected by symptomatic identification and pilot newborn screening
Authors: Sykut‐Cegielska Jolanta , Gradowska Wanda , Piekutowska‐Abramczuk Dorota , Andresen Brage S. , Olsen Rikke K. J. , Ołtarzewski Mariusz , Pronicki Maciej , Pajdowska Magdalena , Bogdańska Anna , Jabłońska Ewa , Radomyska Barbara , Kuśmierska Katarzyna , Krajewska‐Walasek Małgorzata , Gregersen Niels , Pronicka Ewa
Published: November 2010

Long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency (LCHADD) is a fatty acid oxidation disorder with especially high mortality and uncertain long‐term outcome. The aim of the study was to analyze the influence of diagnostic approach on survival in 59 affected children. Referral to a metabolic center was replaced over time by urine/blood testing in centralized metabolic laboratory (selective screening) and by pilot tandem mass spectrometry newborn screening (NBS). Molecular analysis revealed the prevalent mutation in the HADHA gene in all 58 examined cases. Twenty patients died. The number of detections and number of deaths were respectively 9 and 4 (44%) in the patients recognized by differential diagnosis, 28 and 9 (32%) – by selective screening, and 11 and 1 (9%) – by NBS. In 80% of cases the death occurred before or within 3 weeks from the identification. Urgent and active metabolic service remarkably influenced the surviving. The current age of 39 survivors is 0.5 to 23 yrs (mean 7.2 yrs). The disease frequency estimated on the patients number was 1: 115 450, whereas in the pilot NBS – 1: 109 750 (658 492 neonates tested). Interestingly, the phenylalanine level in asymptomatic neonates frequently exceeded the cut‐off values. Conclusions: 1) Urgent metabolic intervention decreases mortality of LCHAD‐deficient patients, but the prognosis is still uncertain. 2) Emergent metabolic reporting and service are crucial also for the survival of neonates detected by NBS. 3) The nationwide selective screening appeared efficient in LCHADD detection in the country. 4) Transient mild hyperphenylalaninaemia may occur in LCHAD‐deficient newborns.
The Formation of East Asian World during the 4th and 5th Centuries: A Study Based on Chinese Sources
Authors: Zhang Xuefeng
Published: November 2010

Adopting the historical periodization and the “ethnic awakening” theory of Konan Naito, this essay discusses the early formation of East Asian states such as Koguryō, Paekche, Silla and Wa during the 4th and 5th centuries, as well as the political order within the East Asian society shaped by the enfeoffment of the Eastern Jin and the Southern dynasties by using Chinese sources. It argues that the cultural influences of the Qin and Han dynasties promoted the ethnic awakening of East Asian peoples, and during the turmoil periods of the Wei, the Jin, and the Division Era these ethnic groups leaped rapidly in their roads of state-formation. The enfeoffment system of the Eastern Jin played significant role in this process, and therefore set up the basic structure of the international relationship in early modern East Asia.
The Historical Changes of the U.S. Policy toward Tibet in the 1940s and 1950s
Authors: Cheng Zaoxia
Published: November 2010

The U.S. policy toward Tibet has always changed in accordance with the U.S. international strategy and the U.S. foreign policy toward China. Before the foundation of the People’s Republic of China, the U.S. admitted Chinese sovereignty over Tibet. During the Cold War, due to its anti-communism strategy, the U.S. began to consider recognizing the independence claim of Tibetan separatists, especially after 1959, when the Dalai Lama was exiled abroad. However, the U.S. government has not openly admitted Tibet is an independent country, because, in the light of the historical development of Tibet within China, claims of independence cannot be substantiated and therefore Tibetan separatism cannot win the recognition or support of the majority of countries in the world.
Effect of abomasal glucose infusion on alanine metabolism and urea production in sheep
Authors: Obitsu T. , Bremner D. , Milne E. , Lobley G. E.
Published: November 2010

The effect of abomasal infusion of glucose (120 kJ/d per kg body weight (BW)0·75, 758 mmol/d) on urea production, plasma alanine-N flux rate and the conversion of alanine-N to urea was studied in sheep offered a low-N diet at limited energy intake (500 kJ/d per kg BW0·75), based on hay and grass pellets. Glucose provision reduced urinary N (P= 0·040) and urea (P= 0·009) elimination but this was offset by poorer N digestibility. Urea-N production was significantly reduced (822v. 619 mmol/d,P= 0·024) by glucose while plasma alanine-N flux rate was elevated (295v. 342 mmol/d,P= 0·011). The quantity of urea-N derived from alanine tended to be decreased by glucose (127v. 95 mmol/d) but the fraction of urea production from alanine was unaltered (15 %). Plasma urea and alanine concentrations (plus those of the branched chain amino acids) decreased in response to exogenous glucose, an effect probably related to enhanced anabolic usage of amino acids and lowered urea production.
Land-use intensification in New Zealand: effects on soil properties and pasture production
Authors: HOULBROOKE D. J. , PATON R. J. , LITTLEJOHN R. P. , MORTON J. D.
Published: November 2010

Land-use intensification requires more farm inputs to sustain or increase farm product outputs. However, a common concern for land-use intensification is the potential deterioration of soil. The North Otago Rolling Downlands (NORD) region of New Zealand is drought prone, and although traditionally limited to extensive sheep farming, there are large-scale conversions to intensive cattle grazing operations such as dairy farming resulting from an irrigation scheme commissioned in 2006. Pallic soils (Aeric Fragiaqualf in US Soil Taxonomy) such as those in the NORD region are prone to soil compaction because of their ‘high’ structural vulnerability under intensive management. To address these concerns, a field trial was established on a common NORD Pallic soil (Timaru silt loam) to determine how land-use intensification affects indicators of soil quality (macroporosity, bulk density, structural condition score, total and mineralizable carbon and nitrogen and earthworms) and pasture production. The treatments compare irrigatedv. dryland pasture and sheepv. cattle grazing on 16 plots. The findings show that soil physical quality responds more quickly to changes in land-use pressure than do biochemical and organic indicators. Both irrigation and cattle grazing, particularly in combination, increased soil compaction; macroporosity on irrigated plots grazed by cattle ranged from 9·1 to 13·3% v/v at a depth of 0–50 mm, compared to dryland plots with sheep grazing (18·9–23·0% v/v). Soil compaction/damage has implications for pasture production, soil hydrology and nutrient movement. Land management practices for intensive cattle grazing of irrigated soil prone to treading damage therefore need to implement high compaction risk strategies to avoid or ameliorate potential changes to soil quality.
Postharvest losses and waste in developed and less developed countries: opportunities to improve resource use
Authors: HODGES R. J. , BUZBY J. C. , BENNETT B.
Published: November 2010

This review compares and contrasts postharvest food losses (PHLs) and waste in developed countries (especially the USA and the UK) with those in less developed countries (LDCs), especially the case of cereals in sub-Saharan Africa. Reducing food losses offers an important way of increasing food availability without requiring additional production resources, and in LDCs it can contribute to rural development and poverty reduction by improving agribusiness livelihoods. The critical factors governing PHLs and food waste are mostly after the farm gate in developed countries but before the farm gate in LDCs. In the foreseeable future (e.g. up to 2030), the main drivers for reducing PHLs differ: in the developed world, they include consumer education campaigns, carefully targeted taxation and private and public sector partnerships sharing the responsibility for loss reduction. The LDCs’ drivers include more widespread education of farmers in the causes of PHLs; better infrastructure to connect smallholders to markets; more effective value chains that provide sufficient financial incentives at the producer level; opportunities to adopt collective marketing and better technologies supported by access to microcredit; and the public and private sectors sharing the investment costs and risks in market-orientated interventions.
Engineering advances for input reduction and systems management to meet the challenges of global food and farming futures
Authors: DAY W.
Published: November 2010

Improvements in farming systems and food supply will come from: increased production efficiencies per unit land area or per unit input of key components such as water or fertilizer; from less negative impact on local and global environments, allowing sustainable biodiversity goals to be integrated with production performance; and from enhanced approaches to bringing global supply and demand in balance, allowing internationally agreed goals for biosphere stability to be shaped, managed and delivered. Each stage will deliver significant improvements to current farming approaches. Modern engineering methods and technology advances have enhanced productivity in all major industries, and farming is yet to make much progress by developing and adopting these technologies. Sensors, control and integrated management systems will be major features, delivering enhanced farming productivity per unit input and per person employed, complemented by decreased environmental impacts and lower losses in the food chain. New insights into modelling and interpreting systems' performance will provide key contributions to optimization and control under complex challenges.
Heterorhabditis atacamensis n. sp. (Nematoda: Heterorhabditidae), a new entomopathogenic nematode from the Atacama Desert, Chile
Authors: Edgington S. , Buddie A.G. , Moore D. , France A. , Merino L. , Hunt D.J.
Published: November 2010

A new Heterorhabditis species of entomopathogenic nematode was isolated from soil of the Atacama Desert in Chile. The new species is characterized by morphometrics of the infective juvenile (IJ) with length (L) = 611 (578–666) μm, head to excretory pore length (EP) = 115 (101–126) μm, tail = 69 (62–79) μm long, (EP/tail) × 100 (E%) = 165 (149–182) and L/maximum body diameter (ratio a) = 28 (25–31). The male has spicules 45 (40–49) μm long, gubernaculum 20 (17–22) μm long and (spicule length/anal body diameter) × 100 (SW%) = 205 (179–249). The hermaphroditic adult has shallow cuticular folds immediately anterior and posterior to the vulva, a slight post-anal swelling and a finely rounded tail terminus. Morphologically, H. atacamensis n. sp. resembles H. safricana, H. marelatus, H. downesi and H. amazonensis, but can be distinguished by characters of adult and IJ stages. In particular, for adult males, H. atacamensis n. sp. differs from H. amazonensis by the number and orientation of the genital papillae and from H. downesi by the position of the excretory pore; by the shape of the female tail terminus from H. downesi and by the position of the IJ hemizonid from H. marelatus. Heterorhabditis atacamensis n. sp. is further characterized by internal transcribed spacer (ITS) and D2D3 rDNA sequences, the closest species, H. safricana, being separated by 13 bp across 730 bp of the ITS (incorporating ITS1 (partial sequence), 5.8S (complete sequence), ITS2 (complete sequence)) and 5 bp across 592 bp of the partial 28S (incorporating D2D3) sequence. The morphological and molecular data confirm that H. atacamensis n. sp. is a valid species.
Identification ofTrichinella spiralisearly antigens at the pre-adult and adult stages
Authors: ZOCEVIC ALEKSANDAR , MACE PAULINE , VALLEE ISABELLE , BLAGA RADU , LIU MINGYUAN , LACOUR SANDRINE A. , BOIREAU PASCAL
Published: November 2010

Three expression cDNA libraries fromTrichinella spiralisworms 14 h, 20 h and 48 h post-infection (p.i.) were screened with serum from pigs experimentally infected with 20 000T. spiralismuscle larvae. Twenty-nine positive clones were isolated from the 14 h p.i. cDNA library, corresponding to 8 different genes. A putative excretory-secretory protein similar to that ofT. pseudospiraliswas identified. Three clones corresponded to aT. spiralisserine proteinase inhibitor known to be involved in diverse functions such as blood coagulation and modulation of inflammation. Screening of the 20 h p.i. cDNA library selected 167 positive clones representing 12 different sequences. The clone with the highest redundancy encoded a small polypeptide having no sequence identity with any known proteins fromTrichinellaor other organisms. Fourteen clones displayed sequence identity with the heat shock protein (HSP) 70. HSPs are produced as an adaptive response of the parasite to the hostile environment encountered in the host intestine but their mechanism of action is not yet well defined. From the 48 h p.i.T. spiraliscDNA library, 91 positive clones were identified representing 7 distinct sequences. Most of the positive clones showed high similarity with a member of a putativeT. spiralisserine protease family. This result is consistent with a possible major role for serine proteases during invasive stages ofTrichinellainfection and host-parasite interactions.
The epitaph for Atthis: a late Hellenistic poem on stone
Authors: Hanink Johanna
Published: November 2010

SGOI 01/01/07 is a highly refined 20-line elegiac epitaph from Cnidus which probably dates to the first century BC. Despite the poem's striking formal features and poetic qualities it has received almost no attention since its first publication by Sir Charles Newton in 1863. The first four sections of this article demonstrate that the inscription represents an important witness to certain epigraphic practices and epitaphic traditions, including those of inscribed dialogue and lament. The final section then presents a reading of the poem which centres on the competing poetics of consolation, memory and forgetfulness proposed by the epitaph's two speaking voices.
De la bigarrure en politique (PlatonRépublique8.557C4–61e7)
Authors: Villacèque Noémie
Published: November 2010

This paper deals with Plato's use ofpoikilosand cognates to describe democracy. It does not argue that Plato'sRepubliccontains empirical analyses of some contemporary event, but supposes that an historical reading of the book is possible and legitimate. Post Peloponnesian War Athenian society experienced profound socio-economic changes. Echoing the aristocratic élite's circumspect anxiety when faced with thenouveaux riches, Plato clearly regards obsessive greediness as one of the root causes of the corruption of any political system. Referring to democracy, the philosopher invents thehimation poikilonor ‘embroidered coat of many colours' metaphor. By materializing the multifaceted concept ofpoikilia, this metaphor gives a single and palpable form to the principaltopoiof anti-democratic rhetoric: thehimation poikilonevokes the motley constitution of the Athenian regime, the tyrant's ostentatious opulence, aped by thedemos turannos, the inconstancy of thedemos, the deceitful character of democracy and, last but not least, its penchant for spectacles.
Thucydides 2.35 and 45.2: against praise
Authors: Winton R.I.
Published: November 2010

This paper suggests that two much-discussed passages in Pericles' Funeral Speech in Thucydides Book 2, the first in 2.35.2, the second in 2.45.2, are more closely related than has previously been recognized: both express a negative view of praise - praise of the fallen; and of their widows. It proposes new interpretations of the passages in question: in the first sentence of 35.2 Pericles is contrasting the splendour of the funeralceremonywith the necessary restraint of a funeralspeech(which Pericles doesnotin this chapter imply was a later addition to the former); in the second sentence of 45.2 he seeks to hearten the widows of the fallen by reminding them, first, that marriage has brought them fulfilment as women and, secondly, that they, asAthenianwomen, can be relied upon to conduct themselves fittingly – in implicit contrast to the most celebrated, and notorious, of Greek women: Helen.
Some Remarks on the Logic of Explanation in the Social Sciences
Authors: Wellmer Albrecht
Published: November 2010

If one were to write a history of the philosophy of science in the spirit of T. S. Kuhn, one would have to consider the model of scientific explanation which Popper proposed and Hempel and Oppenheim developed to be one of the great paradigms of contemporary analytical philosophy of science. This analogue to the historically important paradigms of the individual sciences seems to me to be justifiable for the following reasons: first, the Hempel—Oppenheim model (or HO-model, as I shall call it) claims universal methodological validity; second, discussions on the problem of explanation have centred on this model for some time; third, the recent cognitive progress in this field has been largely the result of the interrelation between criticism of this model on the one hand and its improvement and explication on the other hand; and lastly, this model stands for a particular comprehension of the problems and possibilities of science, a concept of quite important practical consequence.
A Theme for Social Sciences?
Authors: Drake Michael
Published: November 2010

In recent years the quest for the proper form and content of social science studies has been a major preoccupation of academics. The reasons for this are numerous: the very rapid expansion of higher education generally and the particularly marked demand for the social sciences has led to a proliferation of new departments; brash young men have been promoted early (too early, many would say) to positions of power within the universities; the increasingly vocal criticism by the consumers of education – the students themselves – and, perhaps most important of all, a growing desire to re-aggregate human knowledge to counter the trend towards ever narrower degrees of specialism. All these factors have contributed to a mounting dissatisfaction with the traditional ways of studying the social sciences – that is, in almost hermetically sealed departments of economics, of politics, of sociology, and so on. Instead attempts have been made to draw the various social sciences together in studies of particular areas (Britain, Latin America, the underdeveloped world, the ‘new nations’); or of particular processes such as industrialisation, or urbanisation; or of particular problems as associated with, for instance, poverty or race. Each of these represents, of course, a multi- or inter-disciplinary approach to the study of the social sciences. Over the past four years I have been associated with two attempts to produce an integrated, inter-disciplinary course in social sciences. One was a failure; the other, my current preoccupation, is, I think, promising. What I have to say tonight is concerned with an analysis of these two intellectual experiments.
Philosophy and Sociology
Authors: Raphael D. D.
Published: November 2010

We hear nowadays in literary criticism of a type of novel that is an ‘anti-novel’ and of a type of hero who is an ‘anti-hero’. I recently read an article which argued, rather well in my opinion, that the later philosophy of Wittgenstein is an anti-philosophy. One could say the same of the philosophie positive of Auguste Comte, who is often called the father of sociology. The principle with which Comte starts off his philosophy, ‘the fundamental law of mental development’, would put an end to philosophy as traditionally conceived, and would replace it by science. According to Comte, human inquiry goes through three stages. In the first stage, the theological or fictive, men try to give explanations in terms of supernatural beings. At the second stage, the metaphysical or abstract, theological explanation has given way to explanation in terms of abstract entities such as Absolute Motion or Absolute Justice. In the third stage, the scientific or positive, metaphysical explanations have given way to scientific explanations, that is to explanations which do not refer to any unobservable entities but instead simply correlate observable phenomena with each other. This is a picture of intellectual history in which philosophy takes the place of theology and then science takes the place of philosophy
Information, Contemplation and Social Life
Authors: Cioffi Frank
Published: November 2010

Wittgenstein has a remark in which he admonishes us to remember that not everything which is expressed in the language of information belongs to the language game of giving information.

In this paper I want to illustrate how the language of information may be used to disguise the character of the interest we take in social life, an interest whose candid and undisguised manifestations are to be found in literature.
Reason and Passion
Authors: Peters R. S.
Published: November 2010

I Once gave a series of talks to a group of psychoanalysts who had trained together and was rather struck by the statement made by one of them that, psychologically speaking, ‘reason’ means saying ‘No’ to oneself. Plato, of course, introduced the concept of ‘reason’ in a similar way in The Republic with the case of the thirsty man who is checked in the satisfaction of his thirst by reflection on the outcome of drinking. But Plato was also so impressed by man's ability to construct mathematical systems by reasoning that he called it the divine element of the soul. And what has this ability to do with that of saying ‘No’ to oneself? And what have either of these abilities to do with the disposition to be impartial which is intimately connected with our notion of a reasonable man, or with what David Hume called a ‘wonderful and unintelligible instinct’ in our souls by means of which men are able to make inferences from past to future?

It must readily be admitted that there are few surface similarities between the uses of ‘reason’ in these contexts. No obvious features protrude which might be fastened on as logically necessary conditions for the use of the term ‘reason’. But beneath the surface there may be lurking common notions that are, or can be, of importance in our lives. To make them explicit is to give structure and substance to what is often called ‘the life of reason’ and to show that this is not inconsistent with a life of passion as is often thought. This seems eminently worth attempting at a time when many people seem hostile to reason. For those who demand instant gratification, who adopt some existentialist stance, who cultivate violence or mystical experience, or who merely do what others do, are all, in various ways, resisting the claims of reason on them. And what they are resisting is not just the demand that they should reflect and calculate; it is also the influence of passions and sentiments that underlie a form of life.
Authority
Authors: Bell David R.
Published: November 2010

Some things are pervasive and yet elusive. If it can be agreed that the concept of my title and its instances are of this kind, then the observation may serve to justify the present enterprise. The elusiveness of authority is that so often pursued in philosophical enterprise, namely the repeated confident use of a general term by even the unsophisticated, accompanied by the Socratic puzzlement that sets in as soon as a rationale or account of this use is sought. Such puzzlement in the case of the concept of authority is likely to provoke a Cephalitic reaction (this being a coinage to denote those who depart to their mundane duties so that the world may continue to revolve while the philosophers discuss its revolution (vide Plato, Republic bk I)).
Questions on Logical Inference
Authors: Rhees Rush
Published: November 2010

A fundamental notion of the Tractatus is that of the repetition of an operation. The operation specially mentioned is the simultaneous negation represented by the Sheffer stroke. ‘If an operation is applied repeatedly to its own results, I speak of successive applications of it. … In a similar sense I speak of successive applications of more than one operation to a number of propositions’ (5.2521).
How to read Wittgenstein
Authors: Bambrough Renford
Published: November 2010

In the Michaelmas Term 1968 I gave a course of lectures on the Philosophical Investigations. Until then nobody had lectured at Cambridge specifically on that book, though it had been in print for fifteen years and must by that time have been lectured on in nearly every other philosophy department in the English-speaking world. One reason why we were so slow is suggested by a remark that John Wisdom made after hearing Max Black give a lecture on the Tractatus in the early fifties. As we came out of the lecture room he said to me ‘That was a strange experience. I have a clear memory of all that from my early years in Cambridge. And yet in some ways it was like hearing a lecture on Spinoza.’
Wittgenstein on Persons and Human Beings
Authors: Teichman Jenny
Published: November 2010

The last part of Wittgenstein's Blue Book consists of a discussion of Solipsism. In the course of that discussion there occur several remarks (extending over about a page-and-a-half) which are explicitly concerned with the concept of a person and with the criteria of personal identity. This section is replaced in the Philosophical Investigations by half a sentence which reads: ‘… there is a great variety of criteria for personal “identity”’. Wittgenstein has italicised the word ‘identity’, and has placed it in inverted commas: I don't quite know why he does this, but it might be a hint to the effect that there is something slightly suspect about the notion of personal identity.
The ‘Prejudice in favour of Psyghophysical Parallelism’
Authors: Holborow Les
Published: November 2010

Wittgenstein refers to psychophysical parallelism in this apparently prejudiced way in paragraph 611 of Zettel, in the course of a rather remarkable passage. It begins at 605 with the claim that ‘One of the most dangerous ideas for a philosopher is, oddly enough, that we think with our heads or in our heads’. Subsequent sections develop this remark in a way that demonstrates Wittgenstein's rejection of the view that thinking is any sort of process in the head, whether a physiological process or a matter of the operations of ‘a nebulous mental entity’. Indeed he appears to consider that these ontologically opposed alternatives have a common source, in that they both derive from the mistaken view that there must be a mediating process between psychological phenomena such as my present remembering and my experience of the remembered event (cf. Z, 610). If we find no suitable mediating physiological process, we are easily led to assume that there must be a process of a rather different sort, and hence we are led to believe in a ‘nebulous mental entity’. But this whole line of thought in fact depends on a ‘primitive interpretation of our concepts’, an interpretation which we uncritically made at the stage at which we assumed that there must be a process of some sort mediating between the phenomena. We are reminded of Wittgenstein's earlier remarks in Philosophical Investigations, I, 308:
Absolute Ethics, Mathematics and the Impossibility of Politics
Authors: Holland R. F.
Published: November 2010

The idea of absolute goodness and the idea of an absolute requitement tend nowadays to be viewed with suspicion in the world of English-speaking philosophy. The tendency is well rooted and has not just arisen by osmosis from the temper of the times. There are various lines of thought, all of them attractive, by which a recent or contemporary academic practitioner of the subject could have been induced into scepticism about an ethics of absolute conceptions.
The Constitution of Human Values
Authors: Findlay J. N.
Published: November 2010

The present paper is an attempt to study the acts and intentions which set up for the subject, and for the community of subjects, a set of values and disvalues which impose themselves as valid upon everyone, and which everyone must tend to prescribe, or to warn against, for everyone. The acts which set up a formal apophantic and ontology have been studied by Husserl in his Formal and Transcendental Logic, but he has not set out a comparable theory of the acts which set up a universally valid system of values and disvalues. He has not done so because he does not believe in such a system, because his thought goes no further than the values set up for and felt to hold in a given group or society. It is my view that there is an ineluctable progress from these relativistic group-values to a set of values and disvalues holding for everyone, and that moreover in their relation to everyone, and that these values and disvalues have definite and undeniable shapes and locations, even if these shapes also have somewhat nebulous contours. The views I am expounding on this occasion are not new: they are fully set out in my Values and Intentions and my Axiological Ethics and in other writings. Ideas, however, require restatement at intervals, with a suitable change of idiom and emphasis. And I feel my views on this topic to have a claim to truth simply because, quite differently from my views on other topics, and despite constant reflection, they have hardly changed over the last two decades. The inspiration for these views was only in part Husserlian, as I do not think that the emotional and the axiological are really Husserl's strong suit. Strangely enough, that dry thinker Meinong would seem to have had a much richer emotional life and the ability to frame a theory to fit it, than the much easier and at times effusive thinker Husserl. Meinong's 1917 Austrian Imperial Academy treatise, On Emotional Presentation, recently translated for the Northwestern Phenomenology series, is a much more systematic investigation of the presuppositions of value-theory than any writing of a professed phenomenologist. What I have to say will build considerably on Meinong, always a major influence in my thought. But I have also been much influenced in my approaches to value-theory by the transcendental methods of Kant. Kant, I think, could very well have worked out a transcendental deduction of the heads of value and disvalue, a deduction much more illuminating than the dogmatic intuitionism of Scheler and Hartmann, instead of producing the arid triad of categorical imperatives that were all that he actually deduced. Imperatives, I consider, are secondary structures in value-constitution: the primary structures are the ultimate objects of necessary, rational pursuit and avoidance which Kant wrongly thought of as involving heteronomy and a corruption of pure form by matter. There is, I shall argue, nothing more free from extraneous, pathological material than the objects of the pursuits and avoidances in question.
Learning from a Novel
Authors: Beardsmore R. W.
Published: November 2010

There is always a danger in philosophy, that what is intended initially as simply one explanation of some form of activity, should come to be regarded as the only possible form of explanation. Nor does this danger seem to be diminished where a philosopher's aim is itself that of attacking limited notions of what is possible as an explanation. This is one, though not the only, reason why it is often the case that what at first appears as a revolutionary and illuminating solution of certain philosophical difficulties, later gives rise to even more intractable problems of its own.
Allegiance and Change in Morality: A Study in Contrasts
Authors: Phillips D. Z.
Published: November 2010

It has been said that the tendency to make use of examples drawn from literature in discussing problems in moral philosophy is not only dangerous, but needless. Dangers there certainly are, but these have little to do with the reasons offered for the needlessness of such examples. Examples drawn from literature, it is said, introduce an unnecessary complexity into one's philosophising. Indeed, as Peter Winch has pointed out, according to ‘a fairly well-established … tradition in recent Anglo-Saxon moral philosophy … it is not merely permissible, but desirable, to take trivial examples. The rationale of this view is that such examples do not generate the emotion which is liable to surround more serious cases and thus enable us to look more coolly at the logical issues involved’, and it carries the implication that ‘moral concerns can be examined quite apart from any consideration of what it is about these concerns which makes them important to us’.
The Autonomy of Art
Authors: Casey John
Published: November 2010

In his Aesthetic Croce makes some remarks upon the subject of sincerity:

Artists protest vainly: ‘Lasciva est nobis pagina, vita proba’. They are merely taxed (in addition) with lying and hypocrisy. How far more prudent you were, poor women of Verona, when you founded your belief that Dante had really descended to Hell upon his blackened countenance. Yours was at any rate an historical conjecture.
Imagination in the Experience of Art
Authors: Elliott R. K.
Published: November 2010

In this paper I shall not be concerned with the imagination as insight, but only with certain aspects of ‘magical’ imagination, that division of the concept which centres upon the notion of an image. In the Philosophical Investigations (II xi) Wittgenstein makes the extremely interesting remark that when a printed triangle is seen, for instance, as a mountain, it is as if an image came into contact, and for a time remained in contact, with the visual impression (i.e. with the object as seen by me). He goes on to say that in a picture a triangular figure may have some such aspect permanently — in the pictorial context we would read the figure at once as a mountain — but that we can make a distinction between ‘regarding’ and ‘seeing’ the figure as the thing meant. I take him to be contrasting those common experiences in which we see a figure in a picture as depicting a person, or as a ‘picture-person’, with those rarer experiences, referred to by art-critics when they talk of ‘presence’, in which it seems as if the person depicted in the picture is there before us ‘in the flesh’, and I assume that, like Sartre, Wittgenstein would suppose that imagination plays a part in experiences of this latter kind. In this paper I shall be concerned not with this sense of the presence of the object depicted, but chiefly with types of imaginal experience in which the image which seems to come into contact with what is perceived is an image of something which is not depicted or described in the work, but which nevertheless achieves a certain strength of presence. I shall consider, also, some types of imaginal experience which we would not naturally describe as an image's coming into contact with what is perceived. Though I shall relate some of the examples I discuss to my starting-point in Wittgenstein, I do not claim to be elaborating Wittgenstein's remark in a manner which would have been acceptable to him. My aims are to give some indication of the nature and scope of the imaginal experience of art, to defend the aesthetic relevance of this type of experience, and to suggest why the imaginal experience of art has been, and still is, valued.
Representation and Conceptual Change
Authors: Harrison Andrew
Published: November 2010

This paper suffers from a disconcerting generality. I need an excuse for wandering from Wittgenstein's Tractatus to Picasso's drawing of a Weeping Woman, via the philosophy of science and the theory of sense data. The thesis of the paper is that I have such an excuse. These are all areas where the concept of representation either exists in its own right, or has been found to be illuminating by philosophers. An important question is whether it could be the same concept in all these cases. I wish to claim that there is an illuminating common concept, even though to find it may require some fairly drastic modifications of some of the philosophical theses that are involved.
Presentational Objects and their Interpretation
Authors: Pole David
Published: November 2010

The work of artists is to make works of art, and of theorists theoretical works. In our ordinary dealings with such things, elusive as ontologists may find them, we seem to know well enough in either instance how we should regard and handle them. Ontological questions are none the less raised: what species of entity may they be? It is a question, I confess, to which I could never respond with much enthusiasm. My own interest in art is more ordinary; I care about paintings and poems, about what serves to make them good or bad, about how we should look at or read them. Yet it may prove after all that the two issues are not wholly unrelated.
Aesthetic Objectivity and the Analogy with Ethics
Authors: Johnson Oliver
Published: November 2010

Of all the kinds of arguments that philosophers use to support their conclusions, the one type that I find personally to stick longest and most vividly in my mind is the verbal pictures they occasionally draw. Whether this is a result of the fact that I myself think best in pictorial terms or, as I would rather like to believe, is a tribute to the verbal artistry of the writers themselves, it remains true that, for me, the history of philosophy is punctuated with pictures, some pleasing and others perplexing. I need hardly mention Plato; with the Allegory of the Cave, the Myth of Er, the Charioteer of the Soul, and countless others he is beyond question the supreme master of the art. But other examples easily come to mind. I see Descartes seated in solitude before the fire in his dressing gown, suddenly to be surprised by a malignant demon, who appears at his shoulder to whisper insinuatingly into his ear that 2 plus 2 does not equal 4 at all. Or William James on a camping trip with friends trying to decide whether one of their number who keeps circling a tree on which a squirrel clings - and in turn circles the tree at equal speed, keeping the tree between him and his tormenter and never permitting the latter to get into a position behind his back - does or does not circle the squirrel, as he undoubtedly does circle the tree to which the squirrel clings. Or, I see G. E. Moore - and it is this picture that gives rise to the present paper - carefully contemplating two complete, independent, and quite different worlds, trying to decide which of the two is intrinsically better than the other.
Genre and the Experience of Art and Literature
Authors: Dodsworth Martin
Published: November 2010

Like most topics in aesthetics, that of genre is far from simple and for the literary critic has an uninviting air. The questions which arise from its consideration fall under two heads: first, what is a genre? and second, what does it contribute to our understanding of a work of art that we can describe it as belonging to this or that genre? A clear answer to either of these questions is not readily forthcoming: the literary critic who is content to be a critic here very properly hesitates where the philosopher is perhaps inclined to go further. If he does so he will find that the two primary questions about genre have many ramifications, some of which may be suggested by a quotation from René Wellek and Austin Warren's book, Theory of Literature. They ask one question about genre and then re-phrase it: but as they re-phrase their original question it is quite transformed.
Nature in the Light of Art
Authors: Hepburn R. W.
Published: November 2010

Art is without doubt a powerful agent in determining how nature appears to us. Andrew Forge describes seeing tree leaves in sunlight, and ‘thinking Pissarro’. ‘I am wrapped round by Impressionism and the leaves look like brush strokes’. To Harold Osborne, once one has been impressed by Van Gogh's painting of certain objects, ‘it is difficult ever again to see the objects uninfluenced by Van Gogh's vision of them’.
Locke and the Meaning of Colour Words
Authors: Hacker P.M.S.
Published: November 2010

While thinking philosophically we see problems in places where there are none. It is for philosophy to show that there are no problems.

Those of us who are not colour blind have a happy command of colour concepts. We say of trees that they are green in spring, that they are the same colour as grass and a different colour from the sky. If we shine a torch with a red bulb upon a white surface, we say that the surface looks pink although it is white. And if we suffer a bout of jaundice we (allegedly) claim that white things look yellowish to us, although they are not yellow, nor do they (publicly) look yellow. We employ this tripartite distinction unworriedly and unthinkingly. But when, in doing philosophy, we are called upon to elucidate colour concepts it becomes evident that these elementary concepts present intricate problems to the philosophical understanding. It is extraordinarily difficult to obtain a proper surview of colour grammar, and the temptations of philosophical illusion are legion. We go wrong before the first step is even taken, and hence do not notice our errors, for they are implicit in every move we make. We multiply impossibilities seriatim, getting better, like the White Queen, with practice. We then either slide into scepticism, or alternatively exclude it on empirical grounds - appealing, as is so popular in American philosophical circles, to the wonders of science, in particular physics and neurophysiology, to keep the malin genie from the door.
The Status of Sense Data
Authors: O'Connor D.J.
Published: November 2010

In the present state of philosophy in the English-speaking world, to choose to talk about sense data may seem perverse. What could be more boring for one's audience than to attempt variations on so threadbare a theme? And worse, what could be more unfashionable in the aftermath of Wittgenstein and Austin? My reasons for selecting this unpromising topic are twofold. First, the general theme of this series of lectures is empiricism. And whatever meanings we put upon that ambiguous word, it is clear that as a matter of history the problems of perception have been important problems for nearly all those philosophers who would consider themselves to be empiricists. And however unsatisfactory sense datum theories of perception may now be held to be, such theories have been central to the empiricist tradition. Secondly, it is important not to be too much impressed by the fact that a particular philosophical opinion is fashionable or unfashionable. The former certainly does not guarantee its truth nor the latter its falsity. It has often been remarked that philosophical opinions are very rarely refuted. Instead they fall out of vogue only to return some years later in another guise. It is perhaps time to take another look at the notion of sense data. The most ingenious and persistent attacks on analyses of perception in terms of sense data have been at best indecisive, as Professor Ayer showed in his reply to Austin's Sense and Sensibilia.
Wittgenstein on Seeing and Interpreting
Authors: Lewis P. B.
Published: November 2010

In those twenty or so pages of section xi of Part Two of the Philosophical Investigations in which Wittgenstein discusses the concept of noticing an aspect and its place among the concepts of experience, there are three passages which are explicitly concerned with the relations between seeing and interpreting in the experience of noticing an aspect.
New Phenomenalism as an Account of Perceptual Knowledge
Authors: Hobbs Alan
Published: November 2010

To be an Empiricist with respect to knowledge of the natural world, is to insist that all knowledge of that world is rooted in perceptual experience. All claims which go beyond the deliverances of the senses must, in the end, be justified by, and understood in terms of, relations holding between those claims and sensory data. Crucial to the Empiricist case, therefore, is an account of how perception can be a source of knowledge. How can sensory experiences provide, for the owner of those experiences, information about objects and events which exist independently of the experiences themselves?

The following essay scavenges in contemporary sources to arrive at a fresh Empiricist account of perceptual knowledge. There are sufficient parallels with earlier doctrines to call the outcome ‘New Phenomenalism’, but the label is not important. The materials for the thesis have been gathered (and probably twisted) from several current writers, most notably P.F. Strawson and Jonathan Bennett, but no one of these writers is a proponent of the expounded thesis as a whole. As with a composite photograph, no face completely fits.
Empiricism in Science and Philosophy
Authors: Harris Errol E.
Published: November 2010

The term ‘Empiricism’ has had at least two different, though not unconnected, applications in modern thought, one to scientific method and the other to philosophical theory. My intention in this lecture is to try to show that, while these two applications of the term have a common source, their actual referents are widely divergent and in large measure even mutually incompatible.
The Empiricist Account of Dispositions
Authors: Woolhouse R. S.
Published: November 2010

Besides the observable properties it exhibits and the actual processes it undergoes, a thing is full of threats and promises. The dispositions or capacities of a thing — its flexibility, its inflammability, its solubility — are no less important to us than its overt behaviour, but they strike us by comparison as rather ethereal. And so we are moved to inquire whether we can bring them down to earth; whether, that is, we can explain disposition terms without any reference to occult powers.
Nature and Necessity
Authors: Robinson Guy
Published: November 2010

Determinism is a spectre that has haunted our scientifically-oriented culture from the beginning. I happen to think that it is literally a ‘spectre’, a trick of the vision, an appearance with an internal cause only, and that it is no more than the ghost of our own conceptual determinations projected outward into a world in which it has no place and no proper being. From one point of view it is no more than an alienated fantasy involving a number of incoherent assumptions. Of these, one of the most important, and one of the most deeply eroded by much contemporary work, is the assumption that science and scientific understanding is a potentially completable system. From another point of view, however, the deterministic picture seems an inevitable product of scientific activity.