bluuebunny/crossref_metadata_2025 huggingface dataset:
Electrochemical action on the flotation beneficiation of ordinary iron ore concentrate
Authors: Rakhimov Kh. K. , Chanturiya E. L. , Shekhirev D. V.
Published: April 2024

One of the main challenges in processing fresh ferruginous quartzites is to obtain high-quality iron ore concentrates containing more than 70% total iron and less than 1.8% silica to produce DR pellets and hot Briquetted Iron (HBI). Currently, it is widely recognized that the most effective methods to achieve high-quality iron ore concentrates is through reverse flotation using cationic amine collectors in an alkaline medium. However, due to the very fine impregnation of magnetite in quartz, the insufficiently complete release of magnetite even with fine grinding, and the proximity of the flotation (surface) behavior of the separated minerals, high-quality concentrates are not always achievable in the flotation process. Consequently, exploring methods to enhance the efficiency of flotation separation of minerals and improve concentrate quality remains a pertinent issue. Historical studies have shown that electrochemical treatment can adjust the properties of reagents, enhance their effect on specific minerals, and thus control the flotation process. The efficiency of quartz and other silicates flotation by amines significantly depends on the ratio of ionic and molecular forms of the reagent in aqueous solutions of the collector and in the flotation pulp. Altering this ratio can impact the outcomes of reverse cationic flotation of iron ores. It is feasible to change the ratio of the amine forms through electrochemical oxidation or reduction of the reagent solution. Moreover, the electrochemical treatment facilitates the dispersion of the amine in the aqueous medium and its physical adsorption on minerals. Therefore, electrochemical pretreatment of amines can be considered a promising method for intensifying the reverse flotation of iron ore. This paper presents research results aimed at improving the quality of the oversize of the fine screening of ordinary magnetite concentrate from Mikhailovsky GOK, named after A.V. Varichev, through the use of electrochemically treated solutions of cationic amine class collectors in the process of reverse cationic flotation. The research findings confirmed the feasibility of using preliminary diaphragmless electrochemical treatment of reagents Tomamine RA-14 and Lilaflot 811M (esters of monoamine of different composition) for the targeted modification of their properties and for increasing the efficiency of reverse flotation. Consequently, the silica content in the flotation cell product decreased from 1.66–1.7% to 1.51–1.56, with the grade of total iron exceeding 70%.
Determining airflow requirements in mine workings based on field measurements of actual emissions from internal combustion engine equipment
Authors: Senatorov V. A.
Published: April 2024

The increasing complex geological and hydrogeological conditions ore deposit mining, deeper excavation sites, and ambitious business expansion strategies, necessitate the use of high-performance, heavy-duty self-propelled machinery and winning equipment. Such activities significantly strain mine ventilation systems and demand innovative safety measures during mining.

This study assesses the influence of interconnected production variables on the aerological safety of mining operations. It provides real-world data on emissions from diverse sources within mines. The analysis includes an examination of current methodologies for estimating the air volume needed to dilute exhaust gases from diesel-powered machinery. Through numerical simulation that accounts for changes over time, the study was able to predict how exhaust gas concentrations would disperse within mines. These theoretical findings were then confirmed through empirical observations made in actual mining setting The field studies conducted, alongside their thorough analysis, underscored the necessity for adopting new, more sophisticated approaches to calculate airflow requirements in mines operating ICE machinery. A particular methodology developed by the MMI of the NUST MISIS (hereinafter referred to as the Methodology) was put forward as the primary tool for this purpose. The Methodology’s precision and benefits were closely scrutinized, revealing its effectiveness in ensuring aerological safety in mines.
River water quality modelling in South Africa: Considerations, sourcing and accessing of input data
Authors: Mahlathi C D , Brink I C , Wilms J M
Published: April 2024

River water quality modelling relies on a good dataset for model input, calibration and validation to develop a reliable model. Determination of data requirements, and data sourcing towards this purpose in South Africa, are not elementary. Data availability is key throughout the modelling processes, making the sourcing of good data equally imperative. This paper provides starting considerations, and compiles a list of available data sources applicable to river water quality modelling in South Africa. It also provides a background on the included data sources and a general overview of the extent of the databases.
Séquençage nanopore d'isolats de poliovirus v1
Authors: Troman Catherine , Bujaki Erika , Akello Joyce , Fitz Shannon , Shaw Alex , Martin Javier , Grassly Nick
Published: April 2024

ABSTRAIT Ce protocole est adapté du protocole "Détection directe du poliovirus par séquençage nanopore - les échantillons de selles" pour le rendre adapté à une utilisation avec des isolats sous forme liquide ou qui ont été transportés au laboratoire via une carte FTA. Le protocole vise à amplifier la région VP1 du poliovirus avec une seule PCR à l'aide defs amorces Q8/Y7. Nous utilisons des amorces à code-barres car cela simplifie grandement le processus ultérieur de préparation de la bibliothèque. Les séquences d'amorces pour les amorces Q8/Y7 à code-barres se trouvent dans le base de données S1 de Shaw et al (2020). Ce protocole devrait être utilisé avec les réactifs de séquençage chimique Oxford Nanopore kit14 et le séquenceur MinION Mk1B, MinION Mk1C ou GridION. Dans les étapes du protocole, des contrôles de qualité sont inclus et suivent le flux de travail défini dans le document « Quality Control and Data Recording for DDNS ». AVANT DE COMMENCER Ce protocole décrit l’amplification de la séquence VP1 et la préparation de la bibliothèque pour le séquençage. Nous prévoyons que les utilisateurs auront effectué une extraction d'ARN avant ce protocole pour extraire l'ARN du poliovirus. Nous recommandons le kit "MagMAX Viral RNA Isolation" pour ce processus. Amorces VP1 à code-barres: Pour permettre un protocole simplifié, nous utilisons une plaque d’amorce à 96 puits avec 5 µM d’amorce Y7 à code-barres et 5 µM d’amorce Q8 à code-barres dans chaque puit. Chaque puit contient des amorces Q8 et Y7 avec le même code-barres unique, par exemple A1 = Y7 avec code-barres 1 et Q8 avec code-barres 1, A2 = Y7 avec code-barres 2 et Q8 avec code-barres 2, etc. Ces amorces peuvent être commandées prémélangées ou sous forme de deux plaques distinctes qui doit être mélangées au laboratoire.
Nest Building Test v1
Authors: L. Dawson Valina , Dawson Ted , Ko Hanseok
Published: April 2024

Used to assess nigrostriatal sensorimotor function in mice. Based on the Deacon 2006 protocol.
Life Post-SSEAYP: Delving the Concept of “SSEAYP Sick” among Former Participating Youth from the Ship for Southeast Asian and Japanese Youth Program
Authors:   Universiti Teknologi MARA, Zulkefli Mohd Yusof , Ibnu Ireena Nasiha ,   Universiti Teknologi MARA
Published: April 2024

The Ship for Southeast Asian and Japanese Youth Programme (SSEAYP) has been running for 46 years. The Cabinet Office of Japan organises it. This programme aims to foster friendship and mutual understanding between Japanese and Southeast Asian youths. After the Ship for Southeast Asian and Japanese Youth Program (SSEAYP) programme ends, all the former Participating Youths (PYs) will experience a new life adjustment, which is famously known as "SSEAYP Sick". Therefore, this study explores the implications of "SSEAYP Sick" among Former Participating Youths who participated in this program. Additionally, it is crucial to investigate how the SSEAYP programme has affected the PYs.The phenomenological approach is used in this qualitative research technique to comprehend how the PYs feel about a specific phenomenon. Twenty-two informants from ASEAN and Japan were interviewed in-depth to get the data. Thematic transcription was done after a descriptive analysis of the interview material. The study discovered that the PYs viewed this programme as a "bonus" regarding the SSEAYP Sick phenomena. This study's implications have identified three critical causes for the life post-SSEAYP among PYs: culture shock, homesickness, and the intricate process of returning adaptation. In addition, every person possesses unique experiences, thoughts, and viewpoints that have aided their development and moulded them into the people they are today. Keywords: Japan, SSEAYP sick, phenomenology, Southeast Asian, youth.
Important aspects of carbohydrate metabolism disorders development in hematology/oncology patients during therapy with glucocorticosteroids: a review of the literature
Authors: Vatutin N. T. , Sklyannaya E. V. , Gribov V. V.
Published: April 2024

Glucocorticosteroids are highly effective anti-inflammatory and immunosuppressive agents. The drugs were introduced into therapeutic practice from the mid-20th century and are still widely used in the treatment of various diseases. They are an integral part of the treatment of patients with hematological malignancies. One of the clinically significant complications of glucocorticosteroid therapy is steroid-induced carbohydrate metabolism disorders. Diabetes mellitus is one of the main risk factors for the development of cardiovascular diseases, which are the main non-oncological cause of death in the population and a significant treatment complication in patients with malignant neoplasms. Early detection of the disease and improved treatment efficiency increase the survival rate of patients with various types of neoplasms. It is also important to pay attention to quality of life improving in cancer patients after treatment.

The aim of this review is to analyze the pathogenesis features, as well as predictors of early detection and prevention of possible complications of persistent hyperglycemia in patients with hematological malignancies.
Pathogenesis and therapy of anemia in patients with inflammatory bowel diseases
Authors: Rybina O. V. , Sakhin V. T. , Gubkin A. V. , Rukavitsyn O. A.
Published: April 2024

Background. Anemia represents one of the most frequent complications in inflammatory bowel disease and severely impairs the quality of life of affected patients. The etiology of anemia in inflammatory bowel disease patients can be multifactorial, often involving a combination of iron deficiency anemia and anemia of chronic disease. The choice of therapy, focused on the leading cause of anemia, allows for individualized therapy, minimizing the risk of side effects and the cost of therapy.

Aim. A comparative analysis of blood parameters before and after treatment was performed.

Materials and methods. For 5 years, 47 patients (15 women, 32 men) with inflammatory bowel disease with a median age of 48 years (from 28 to 65 years) were studied. Two groups were formed: patients with iron deficiency anemia and patients with anemia of chronic disease. Patients with combination of iron deficiency anemia and anemia of chronic disease D (n = 21) were not included. A division was also made according to the type of treatment performed.

Results. In the iron deficiency anemia group, a statistically significant increase in hemoglobin level was revealed as a result of the use of intravenous iron. During therapy with oral iron and B vitamin therapy, as well as therapy aimed only at correcting gastrointestinal tract pathology, no reliable dynamics of the studied parameters was observed. In the anemia of chronic disease group, there were no significant changes in red blood cell parameters with any of the treatment options (p >0.05).

Conclusion. The effectiveness of various therapeutic approaches to correct anemia is controversial. Further follow-up and an increase in the sample size are needed, which will help individualize therapy and improve the patients’ quality of life.
CONCEPT OF THE ADMINISTRATIVE AND LEGAL PROTECTION MECHANISM OF PUBLIC INTERESTS IN THE INVESTORS’ INSTITUTIONS ACTIVITIES
Authors:   Ivano-Frankivsk branch of Open International University of Human Development «Ukraine», Vazhynskyi V. M.
Published: April 2024

The article is devoted the studying of the existing approaches of administrative law scholars to the understanding of the concept of «mechanism». The purpose of the article is the formation of the author’s vision of the concept of administrative and legal protection of public interest in the activities of institutional investors. The author emphasizes the multifaceted nature of the concept of «mechanism» in legal science, pointing out that it is most often found in scientific works in the following phrases: «mechanism of legal regulation», «mechanism of rights protection», «mechanism of ensuring rights», «mechanism of health protection», «law-making mechanism», «management mechanism». The author considered the concept of the mechanism of administrative and legal protection of the public interest in the activities of institutional investors from the standpoint of praxeology, noting that the protection mechanism allows assessing the effectiveness or ineffectiveness of the entire public governance system. The mechanism of public governance for the purpose of protecting public interests in the activities of institutional investors is considered as part of the entire mechanism of public governance of the activities of institutional investors, which is used to eliminate contradictions (potential or real) between various subjects of the public governance system in order to ensure the protection of public values. As a result, the author offers his definitions of the mechanism of public governance of the activities of institutional investors for the purpose of protecting the public interest of the element of the system of public governance of the activities of institutional investors, which characterizes its effectiveness and consists of a complex of forms and methods, with the help of which governance influence is ensured on all participants of the public governance system with the aim of eliminating contradictions between their interests (potential or real) to ensure the implementation and observance of the interests (values) of society.
Resolution of the Council of Experts “The choice of antihypertensive therapy in patients with hypertension and obstructive sleep apnea syndrome”
Authors: Barbarash Olga L. , Garganeeva Alla A. , Gogolashvili Nikolay H. , Kashtalap Vasily V. , Miller Olga N. , Nevzorova Vera A. , Petrova Marina M. , Protasov Konstantin V. , Chumakova Galina A. , Tsygankova Oksana V. , Yakovlev Alexey V.
Published: April 2024

On June 24, 2023, a meeting of the Council of Experts was held in videoconference mode with the support of Merck LLC, dedicated to the choice of antihypertensive therapy in patients with arterial hypertension and obstructive sleep apnea syndrome.
OUTPATIENT FOLLOW-UP OF PATIENTS WITH ATHEROSCLEROSIS OF LOWER EXTREMITIES: PROMISING WAYS TO IMPROVE RESULTS
Authors: Sumin Aleksey N. , Shcheglova Anna V. , Medvedeva Yulia D. , Ivanov Sergey V. , Kashtalap Vasily V. , Barbarash Olga L.
Published: April 2024

Highlights

The article shows the positive impact of 3-year cardiology follow-up in patients with atherosclerosis of lower extremities.

 

Aim. To study the impact of outpatient cardiology follow-up in patients with peripheral artery disease on the prognosis and the frequency and outcomes of surgical interventions.

Methods. The study included 585 patients with peripheral artery disease who underwent outpatient follow-up - by a surgeon (n = 131) and a cardiologist (n = 454). The groups were compared according to the main clinical and anamnestic data and type of drug therapy. After 3 years, the incidence of adverse outcomes (nonfatal myocardial infarction, nonfatal stroke, new amputations and deaths) and factors associated with adverse outcomes in the selected cohort were evaluated.

Results. The group of patients who were followed by cardiologist received optimal drug therapy more often compared with patients followed by surgeon: β-blockers (80.4% vs. 32.8%; p < 0.001), angiotensin converting enzyme inhibitors (61.0% vs. 38.2%; p < 0.001), statins (87.0% vs. 63.4%; p < 0.001). Within three years, fatal outcome was more common in the group of patients followed by surgeon (13.0% vs. 6.8%, p = 0.023). The factors that positively affected the prognosis of patients were cardiology follow-up (OR 0.34; 95% CI 0.17–0.7; p < 0.001), taking aspirin (OR 0.12; 95% CI 0.06–0.22, p < 0.001) and statins (OR 0.11; 95% CI 0.05–0.21; p < 0.001).

Conclusion. The results of this study confirm the need for more effective cardiology follow-up of patients with peripheral artery disease. This will improve the results of treatment and reduce the number of complications. Further research in this area can help determine the optimal strategies for follow-up and improve the quality of life of patients with peripheral artery disease.
AUDITORY AND VERBAL MEMORY DISORDER IN YOUNG SCHOOLCHILDREN WITH CONGENITAL HEART DEFECTS
Authors: Rumiantseva Aleksandra A. , Kameneva Veronika A.
Published: April 2024

Highlights

The presented literature review points to new questions associated with cognitive impairment in patients with congenital heart defects. We propose that cognitive and behavioral impairments in patients with CHD are common, but their development trajectory and degree of severity depend on the CHD subtype.

 

Aim. To study the features of auditory and verbal memory in young schoolchildren who underwent cardiac surgery.

Methods. The study included 104 children from 7 to 10 years old, who underwent on-pump cardiac surgery for congenital heart defects at the Research Institute for Complex Issues of Cardiovascular Diseases in the period from 2019 to 2022. We analyzed anamnesis data, clinical and hemodynamic picture, the risk of mortality from surgery according to the RACHS scale, and assessed the auditory and verbal memory according using methodical manual by T.A. Fotekova and T.V. Akhutina (block 1 series 3, block 2 series 1) during 1-year follow up.

Results. All children had presented with stage I chronic heart failure (functional class II) at the time of hospitalization. The outcome of surgery was mostly positive a year after the surgery: children had no heart failure symptoms or hemodynamic disorders, however, 80% of children had auditory and verbal memory impairments.

Conclusion. In addition to standard methods of examining children with congenital heart disease, it is necessary to introduce a comprehensive interdisciplinary approach that would include the assessment of neurocognitive status before and after surgery.
APPLICATION OF OBJECT DETECTION TECHNOLOGY IN AORTOGRAPHY KEYPOINT TRACKING
Authors: Laptev Vladislav V. , Kochergin Nikita A.
Published: April 2024

Highlights

The practical significance of the work lies in the fact that the presented aortography data visualization system is an effective tool for visually assisting surgeons during transcatheter aortic valve implantation interventions, supporting real-time operation mode. The proposed data preprocessing algorithm, which improves image quality with minimal performance costs, complements the system, allowing specialists to achieve the best result.

 

Abstract

Aim. The aim of this study is to develop a visual assistance system for transcatheter aortic valve implantation procedures.

Methods. To address the stated objective, our own dataset consisting of 35 videos of the intervention was used. The visualization system is based on the approach of detecting key points in aortography, utilizing “Object detection” technology with the application of YOLO family artificial neural networks. To achieve the best result, we proposed a method to enhance the quality of input data using convolutional neural networks, specifically the «Autoencoder» technology.

Results. The results of the study revealed that the convolutional autoencoder model is capable of restoring the informativeness of noisy input images from 40 to 75%, thereby increasing the accuracy of object detection in images. The presented real-time tracking system for facilitating TAVI procedures achieves a final accuracy of 51.9% according to the Mean Average Precision (MAP) quality metric. The visual assistance system can recognize and track key points indicating the location of the aortic root, delivery system, and heart valve prosthesis during surgery. The practical significance of the work lies in the fact that the presented aortography data visualization system is an effective tool for visually assisting surgeons during interventions, supporting real-time operation mode.

Conclusion. The proposed data preprocessing algorithm, which improves image quality with minimal performance costs, complements the visualization system, allowing specialists to achieve the best results.
TRANSCATHETER AORTIC VALVE REPLACEMENT: FROM IDEA TO IMPLEMENTATION
Authors: Ganyukov Vladimir I. , Tarasov Roman S. , Kolesnikov Alexey Yu. , Ganyukov Ivan V.
Published: April 2024

Highlights

Transcatheter aortic valve replacement is an innovative trend in modern cardiovascular surgery. This minimally invasive image-guided endovascular technology is becoming more and more safe, nowadays it can involve a minimalistic approach in which the aortic valve replacement is performed without incisions, anesthesia and cardiopulmonary bypass - patients are conscious and spontaneously breathing. The article describes a paradigm shift in modern cardiology, in which the concept of treating patients with degenerative aortic valve stenosis has changed over the 20 years of existence of the transcatheter replacement, starting as a method used only in small number of extremely high-risk patients unsuitable for cardiac surgery and now being the most prevalent treatment modality in patients at intermediate and even low surgical risk. The main clinical and technical principles of transcatheter aortic valve replacement, as well as the prospects for the development of this technique, are highlighted.

 

Abstract

Transcatheter aortic valve replacement technique was first implemented about 20 years ago, in April 2002. A quarter of a century ago, specialists involved in image-guided surgery would have never believed that they would perform transcatheter interventions on heart valves. Transcatheter interventions are an alternative to open-heart surgery for acquired heart disease. Transcatheter heart valve replacement or repeat transcatheter aortic valve replacement, which do not require incisions, cardiopulmonary bypass, and in some cases general anesthesia, to this day continue to be perceived as revolutionary and breakthrough, saving the lives of many patients. The article presents the main milestones in the development of image-guided endovascular surgery and transcatheter aortic valve replacement technique, the number of which in the United States and several European countries increases by 10–15% annually, reaching hundreds of thousands per year. The etiology and pathophysiology of aortic stenosis, the technique of transcatheter aortic valve replacement and the outcome of this promising minimally invasive procedure are presented.
DEVELOPMENT AND SUBSTANTIATION OF PROMISING MODELS OF MEDICAL CARE FOR DISEASES OF CIRCULATORY SYSTEM IN INDUSTRIAL REGION. 2010–2023 RESULTS
Authors: Artamonova Galina V. , Bazdyrev Evgeny D. , Makarov Sergey A.
Published: April 2024

Highlights

We have identified regional peculiarities of traditional and non-traditional cardiovascular risk factors.

We have defined and characterized clinical and organizational characteristics of the specialized care, prevention, and treatment of diseases of the circulatory system in the Kemerovo region - Kuzbass.

Moreover, we have described the principles of innovative organizational models for improving care for patients with diseases of the circulatory system, focused on the needs of outpatient organizations.

 

Abstract

The review presents the main research findings obtained at the Department of Optimization of Medical Care for Cardiovascular Diseases of the Research Institute for Complex Issues of Cardiovascular Diseases over the past 13 years of work. The uniqueness of the obtained data lies in the fact that we have identified regional peculiarities of cardiovascular risk factors in residents of an industrial region (using the Kemerovo region data). Data on monitoring of health and risk factors served as the basis for the development of innovative organizational models for improving care for patients with diseases of the circulatory system from the stage of primary care to tertiary care using a systematic and integrated approach, and situational analysis. Management decisions within models are based on international quality standards that reaffirm that risk-based management, the role of personnel and the work environment are the integral to the improvement of performance and the achievement of the main goals of medical organization. Using the project approach, we have implemented management tools for internal quality control and safety of patients and personnel.
EFFECTIVENESS OF A BIOLOGICAL PROSTHESIS IN THE TREATMENT OF TRAUMATIC FEMORAL ARTERY INJURIES
Authors: Sukovatykh Boris S. , Aptarov Zainiddin N. , Sukovatykh Mikhail B. , Gordov Maksim Yu. , Grigoryan Arsen Yu.
Published: April 2024

Highlights

The prevalence of vascular injuries during military engagements can reach 20%. In the thigh, vascular injuries are the second most frequent type of injury. Vascular replacement using a graft is required in case of a femoral artery injury with length of more than 10 cm. If autologous blood vessels are not available for replacement, specialists resort to using a synthetic prosthesis. Selection of an appropriate prosthesis remains a priority for vascular surgeons.

 

Aim. To evaluate the outcome of vascular replacement using a biological prosthesis derived from bovine internal thoracic arteries for the treatment of femoral artery injuries.

Material and methods. The study involved 30 patients with femoral artery injuries. The analysis focused on the indicators of comprehensive examination and treatment of these patients, who were divided into 2 statistically homogeneous groups of 15 people each. In the first group, a biological prosthesis derived from bovine internal thoracic artery was used to replace the artery, and in the second group, a large subcutaneous vein was used. The results of treatment were evaluated by the number of postoperative complications, the durability of grafts and the quality of life of patients.

Results. There were no fatal cases. In the first group, 6 (40%) patients suffered postoperative complications, and in the second group – in 5 (33.3%) patients. After 5 years, 12 (80%) grafts remained functioning in the first group, and 13 (86.7%) grafts in the second group. The physical component of the health of patients in the first group was equal to 60.6 ± 3.2, in the second group – 62.5 ± 3.4, and the psychological component of health 58.7 ± 2.8, and 59.5 ± 3.1, respectively. There was no statistical reliability between the indicators of the groups (p > 0.05).

Conclusion. Biological prosthesis derived from bovine internal thoracic arteries for the treatment of femoral artery injuries is quite effective.
PHYSICAL AND MECHANICAL PROPERTIES OF CONDUITS DURING THE FORMATION OF THE OUTFLOW TRACT INTO THE PULMONARY ARTERY
Authors: Soynov Ilya A. , Rzaeva Ksenia A. , Gorbatykh Artyom V. , Voitov Alexey V. , Arkhipov Alexey N. , Nichay Natalya R. , Kulyabin Yuri Y. , Manukyan Sergei N. , Bogachev-Prokophiev Alexander V.
Published: April 2024

Highlights

We have evaluated the rigidity and distensibility of conduits in the long-term period using transthoracic echocardiography. The assessment of elastic properties will make it possible to predict degenerative changes in the conduit and choose the optimal prosthesis.

 

Abstract

Aim. To evaluate changes in the rigidity and distensibility of conduits in patients after the formation of an outflow tract into the pulmonary artery in comparison with the control group of “healthy” children.

Methods. The prospective non-randomized two-center study included 58 people with right ventricular dysfunction who underwent primary conduit implantation between the ages of 3 and 15 years. To assess the elastic properties of the pulmonary artery, a control group of 25 patients (healthy children who agreed to participate in the study) was introduced. The study was carried out at the Meshalkin National Medical Research Center and the Almazov National Medical Research Centre. All patients were divided into 4 groups: healthy children (n = 25), formation of the outflow tract with a pulmonary homograft (n = 28), and formation of the outflow tract with Contegra conduit (n = 19), formation with a xenopericardial conduit (n = 11).

Results. The only differences between the groups were the RV EDV index, RV CVD index, RV FIP, severe pulmonary regurgitation, and tricuspid regurgitation. There is a significant difference between the groups in the long-term period (after 12 and 24 months), both in terms of rigidity and elasticity. The only difference in the long-term period after 12 months was the degree of tricuspid regurgitation, which was significantly lower in the control group. After 24 months, the peak gradient between the right ventricle and the pulmonary artery was different, which was significantly higher in the group of xenopericardial conduits and the degree of pulmonary regurgitation, which was significantly lower in the control group.

Conclusion. The conduits show higher stiffness in the long-term period in contrast to the normal pulmonary artery, which may affect the durability of the conduits.
An evaluation of the adhesive capabilities of dry adhesive gecko tapes produced using diffraction gratings
Authors: Ko Natalie Mei Ting
Published: April 2024

Certain types of geckos can scale walls, and dry adhesives called “gecko tape” have been developed to reproduce these abilities. However, many of these gecko tapes are difficult and inefficient to produce, especially in large quantities or sizes. This project aims to produce gecko tapes by casting 2-part silicone onto diffraction gratings of various line densities and evaluate the resulting gecko tape’s performance. It was hypothesized that the maximum sliding force of a piece of gecko tape will increase proportionally to the diffraction grating line density. It was also hypothesized that as the angle between the force direction and the interface between the gecko tape and the surface increases, the force required to fully detach the gecko tape off the surface will decrease. These hypotheses were made based on the understanding of an increased line density that results in increased attractive van der Waals forces between the gecko tape and the attached surface, and an increased peeling angle that results in decreased van der Waals forces. Overall, the data collected supported the hypotheses. The maximum sliding force of the gecko tapes increased proportionally to the diffraction grating line density in a linear fashion. The maximum peeling force of 1800linesmm-1 gecko tapes exponentially decreased as the peeling angle increased from 0° to 90°. Gecko tapes produced using an 1800linesmm-1 diffraction grating had an average maximum sliding force of 0.28Ncm-2 and an average maximum peeling force of 2.34N at a 0° angle. More extensive research could be done to better understand the properties of diffraction grating gecko tape, which would allow further directions of research on biomimetics to be justified.
Advantages of red light-operated optogenetic tools in neuroscience
Authors: Saravanan Dhanya
Published: April 2024

Optogenetics is a technology that combines genetic engineering and light stimuli to manipulate specific groups or types of cells. It allows researchers to have spatial and temporal control, therefore showing great promise in the field of neuroscience [1]. In regards to neuroscience, the technology allows researchers to conduct advanced experiments to uncover the functions of specific brain areas. Optogenetics can also be used in the therapeutic side for neurological diseases by manipulating dysfunctional cells to restore function and alleviate disease symptoms [1].
Smart specialization: origin and state of the art
Authors: Gamidullaeva L. A.
Published: April 2024

Purpose: is to identify state of the art, key aspects and distinctive characteristics of the smart specialization concept based on a study of the current state and the initial prerequisites for its formation, including linkages with other theoretical approaches.

   Methods: theoretical provisions of regional and spatial economics, innovative development, and economic geography by Russian and foreign scientists were used for conducting the research. Тhe methods of bibliometric, statistical and content analysis of literary sources constituted a methodological framework for the study. A systematization of publications for 2012–2021 was grounded on thematic samples from eLIBRARY.ru, Scopus and Web of Science databases. An analysis of text array content was conducted with the aim of further critical interpretation of the revealed patterns and identifi cation of promising research directions.

   Results: it was found, that despite the fact that the concept of the smart specialization was based on many previous theoretical approaches, it made a signifi cant contribution to the new political vision of regional development. It is shown how the initially sectoral approach, through the use of the postulates of economic geography, was transformed into the territorial concept. The conducted bibliometric and content analyses of literary sources made it possible to identify the inherent characteristics of the concept, principles and tools for its implementation, as well as formulate the author’s defi nition of the smart specialization approach.

   Conclusions and Relevance: the importance of smart specialization consists of the following aspects. Firstly, substantiating the need for differentiated regional policy for various types of regional innovation systems. Secondly, scientifi c and practical substantiating the importance of the related diversifi cation approach to regional development to stimulate structural changes that are signifi cant for economic dynamics. Thirdly, focusing on interregional interaction to ensure complementarity of scientifi c and technological regional development.
The role of artificial intelligence in building an adaptive educational environment
Authors: Izmailova M. A.
Published: April 2024

Purpose: of the article is to study the influence of artificial intelligence on the construction of an adaptive educational environment that takes into account the positive and negative impact of artificial intelligence, as the core of digital technologies, on the well-being of participants in the educational process.

   Methods: the work uses a complex of theoretical methods, including axiomatic, formalization, abstraction, logical analysis, historical retrospection. The most signifi cant practical research methods include statistical, operationalization and evaluation, comparative analysis.

   Results: the article provides a statistical substantiation of the demand for artifi cial intelligence in the education. The current educational problems are shown, in solving which it is advisable to use artifi cial intelligence. The article describes the trends in the use of artificial intelligence in the Russian education. The interpretation of the adaptive educational environment is given and the possibilities of using artificial intelligence as a tool for its construction are shown. The logical sequence for constructing an adaptive intelligent teaching system is proposed. The analysis of the impact of digital technologies used in hybrid learning (including artifi cial intelligence) on the well-being of participants in the educational process was carried out. The need for a rational, balanced and cautious approach to the use of artifi cial intelligence in education is emphasized, which gives rise to numerous ethical problems, ignoring which can negatively aff ect the values of education.

   Conclusions and Relevance: in the context of digitalization of the economy and society, the key technology of which is artifi cial intelligence, education is facing technological challenges that force it to adapt to new operating conditions. The penetration of artifi cial intelligence into the field of education is the pattern of scientific and technological progress that cannot be resisted. The positive aspects and threats of using artificial intelligence in education should be critically assessed, and informed decisions should be made on this basis. Considering the specifics of the educational environment in which the foundation of personality is laid, and the need to preserve the values of education as a factor of cultural progress, priority in goal-setting and the meanings of education should remain with a person whose assistant can be artifi cial intelligence.
A Review on the Policy Response of Monster Parents in Japan
Authors:   The Korea Association of Yeolin Education, Kwag Soyoung , Kim Kayoung , Chung Jae Young
Published: April 2024

This study aims to examine the analysis and forecasting of the issue of 'monster parents' in Japan. The focus is on 11 research papers published since 2007 that deal with the 'monster parents' topic. The study analyzes the social background, definition, types, characteristics, causes, and response strategies of monster parents. The findings indicate that 'monster parents' are guardians who repeatedly make unreasonable or frequent and continuous demands. The phenomenon of 'monster parents' started appearing in the early 2000s and has continued to be a social issue to the present day. The emergence of monster parents is attributed to factors such as educational reforms and the weakening of teachers' rights. The Japanese government has implemented various response policies, including the distribution of complaint response manuals and the establishment of expert-led complaint response bodies, but these have been deemed insufficient solutions. The educational landscape in Korea currently exhibits a pattern similar to that of Japan in the 2000s. Therefore, the Korean government should consider Japan's case and develop proactive policies based on a detailed analysis of the domestic educational field.
NIE Instructors' Experiences in Teaching 'Newspaper in Education': A Phenomenological Study
Authors:   The Korea Association of Yeolin Education, Kim Hyangran , Lee inhoi
Published: April 2024

The purpose of this study was to comprehend the significance of newspaper utilization in education, as experienced by NIE instructors. To achieve this goal, the purpose of this study was to understand the meaning of the NIE instructors’ experience in teaching “Newspaper In Education”. To achieve this goal, the meaning of experience was derived using Colaizzi's analysis method among the phenomenological research methods for four NIE instructors who founded the Jeju NIE Society, a social education organization. As a result, it was classified into three categories, eight major topics, and 24 sub-topics, and the three categories were 'Meet NIE', 'In Conflict and Confusion', and 'Growing with NIE', respectively. The main conclusions based on these results are as follows. First, NIE helps form a life attitude to contribute to society by leading to more important recognition of community values. Second, if an NIE course is prepared for public education and applied to students, it will not only help develop core competencies in the 2022 revised curriculum, but also play a good role in solving video-oriented problems. Third, if you want to get out of the NIE recession, the first priority should be to develop the capabilities of instructors. This study is meaningful in that it grasped the nature and meaning of the NIE instructors experience based on the vivid experiences of field instructors.
Value orientations nominating the future teacher as an object of prognostic description
Authors:   Volgograd State Agrarian University, Chernyaeva A. V. , Shagina Yu. V. ,   Volgograd State Agrarian University
Published: April 2024

The role of values in individual and social consciousness has been discussed for a long time. The issue of interpretation of value orientations that determine the process of choosing life strategies and regulating the social behavior of a person and society is equally significant and studied. The purpose of the work is to identify basic values and analyze the parameters of value orientations both of an individual and of a social group of student youth. The reflexive methodology for identifying values was chosen as a research method. The empirical technology of double open questions made it possible, based on freely recorded values and individual conceptual ideas, to identify the key value orientations of students, which can be taken as a basis when developing effective technology solutions for optimizing the learning of university students. The study involved 90 students of pedagogical training program at the Volgograd State Agrarian University aged from 18 to 26 years, of which, there were 52 girls and 38 boys. Quantitative and qualitative assessments allowed considering the features of life values according to their degree of popularity, significance and satisfaction with them of future teachers as part of student youth and one of the forms of national identity manifestation. The results of the study showed that family, health, and material well-being are highly popular in the structure of life values of future teachers. Patriotism, efficiency in business and family are considered significant values in life. The greatest satisfaction with the state was revealed for such values as sharing experience with young people, family and education. Such orientations as dignity, honor, faith, goodness, joy, happiness, responsibility, and environment improvement are weakly represented.
Development of tools to support the enterprise digital transformation project management system based on big data
Authors:   Togliatti State University, Iskoskov M. O. , Mitrofanova Ya. S. ,   Togliatti State University
Published: April 2024

In the context of the digital economy development and the transition to the data economy, it is necessary to work out iteratively the strategy of digital transformation of the enterprise on an ongoing basis, as well as optimize the digital project portfolio to achieve strategic business goals and obtain new quality and value of the business model and business processes due to the digitalization advantages. The study identifies the directions for the formation of a management system model that correspond to modern trends in enterprise digitalization and intellectualization based on approaches, tools and standards of project management. The conducted theoretical research allowed developing a set of tools that includes a conceptual model of the digital transformation project management system, a methodology for evaluating the effectiveness of the analytical subsystem for managing digital transformation projects based on big data and a generalized model for forming a strategy for managing digital transformation projects of an enterprise. The proposed authors’ methodology for evaluating the effectiveness of the analytical subsystem for managing digital transformation projects based on big data can be used as one of the tools for assessing the digital maturity of an enterprise and the level of use of big data tools in management. This will allow identifying problem areas for the development of a management system based on big data, as well as reasonably forming an analytical infrastructure for digital transformation corresponding to the transition towards the data economy. The developed conceptual model of the digital transformation project management system is aimed at forming an effective portfolio taking into account risks, the external and internal context of the enterprise, and includes a mechanism for choosing an approach (flexible, classic, hybrid) to managing digital transformation projects.
Реализация педагогических условий проектирования здоровьесберегающей среды в начальной школе
Authors: Искандарова С.Б.
Published: April 2024

В статье рассматривается проектирование системы расширения спектра образовательных мероприятий и дел, направленных на оздоровление, сохранение и укрепление здоровья учащихся начальных классов. Применение активных методов обучения на уроках, а также применение технологии В.Ф. Базарного «Развивающее здоровье-принципы конструирования учебно-познавательной деятельности».
Сравнительный подход в преподавании грамматики иностранного языка
Authors: Наймушин А.И.
Published: April 2024

В статье рассматривается сравнительный подход в обучении грамматики иностранного языка. Ему противопоставляется выборочный подход на основе изучения грамматических явлений только целевого языка. Приводится список тех явлений, с которыми сталкиваются обучающиеся в изучении русского (РЯ) и английского (АЯ) языков. Несмотря на различия в организации грамматического строя обоих языков, рассматривается возможность их сравнения на примере глагола. Представлены такие аспекты глагола как время, вид и направленность. Предпринята попытка провести сопоставительное анализ двух языков с разным грамматическим строем.
QR-код как инструмент digital-маркетинга: сущность, виды, применение
Authors: Ботт Н.С.
Published: April 2024

В статье исследуется влияние и использование QR-кодов на маркетинговые коммуникации в эпоху цифровизации. В ней рассматривается сущность, а также преобразование QR-кодов из учетного инструмента в маркетинговый. Рассматриваются различные типы QR-кодов: статические, динамические и микро, их функциональные особенности и сферы применения. Особое внимание уделено использованию QR-кодов в маркетинговых взаимодействиях с потребителями. Также приводятся примеры применения QR-кодов в маркетинговых коммуникациях.
Что ищут пациенты, перенесшие инсульт и их родственники в интернете
Authors: Торосян Т.Л.
Published: April 2024

Актуальность исследования обусловлена высокой частотой инсультов разных типов по всему миру. Данная тенденция продолжает сохранять высокий уровень и требует тщательного исследования. В России ежегодно случается около 435,4 тыс. инсультов, по данным 2019 года. [1;2;3;4]. Огромное число пациентов и их родственников, которые непосредственно будет осуществлять уход, оказавшихся в этой ситуации порой не знают куда обратиться и что делать после выписки из сосудистого центра. Определение количества потенциальных пациентов, которые могут быть готовы к реабилитации. Также подтвердим или опровергнем гипотезу о том, что каждый пользователь делает 3 запроса в интернет. Данная информация поможет нам рассчитать аудиторию для работы с цифровыми маркетинговыми инструментами на следующих этапах. На основе этого массива данных запросов в интернете удалось сформировать семантическое ядро запросов в виде 50 фраз. Проанализировать общее количество запросов Pунета на тематику постинсультной реабилитации и подтвердить вводимый ранее коэффициент: на 1 пользователя приходится 3 запроса. Также появилась возможность выявить поведенческую последовательность пользователей при поиске информации – о реабилитации, где, столько стоит, реабилитация на дому. Весь выявленный массив данных будет полезен при формировании модели коммуникации с пациентами.