bluuebunny/crossref_metadata_2025 huggingface dataset:
MULHERES, MIGRANTES E MILITANTES: A BUSCA POR UMA VOZ PRÓPRIA
Authors: ElHajji Mohammed , Domingues Claudia
Published: November 2018

No afã de contribuir à compreensão do atual fenómeno de ativismo de mulheres migrantes, o presente trabalho tem por objetivo analisar a construção discursiva histórica da condição da mulher migrante até a experiência de uma das voluntárias do coletivo “Equipe de Base Warmis – Convergência das Culturas”, um Movimento Humanista, que tem por missão facilitar e estimular o diálogo entre as culturas, denunciar e lutar contra toda forma de discriminação contra a mulher migrante. Também apresentaremos algumas estações expressivas do processo de luta das mulheres migrantes por agência e autonomia. Antes excluídas, ignoradas e caladas, as mulheres em geral e as migrantes em particular se organizam associativamente para disputar seu direito à fala e conquistar a cidadania social, cultural e política. Metodologicamente, longe de se engessar na lógica formal de causalidade linear, a nossa reflexão se estrutura em torno de eixos factuais e conceituais complementares suscetíveis de restituir o significado da problemática em suas diversas dimensões, assim como narrativas de histórias de vida.
REPRESENTAÇÕES SOCIAIS DE IMIGRANTES LATINO-AMERICANOS EM ESPANHA SOBRE IMIGRAÇÃO E IMIGRANTES
Authors: Moura Giovanna Barroca , Ramos Natália
Published: November 2018

Este estudo se fundamentou na Teoria das Representações Sociais (TRS), debruçando-se sobre o contexto de vida de imigrantes latino-americanos que vivem na cidade de Valência/ES. O objetivo desta pesquisa, foi apreender as representações sociais (RS) dos imigrantes latino-americanos (argentinos, colombianos, bolivianos, brasileiros e equatorianos) residentes na cidade de Valência (Espanha) sobre os construtos: imigração e imigrante. Participaram 386 imigrantes latinos que responderam ao Teste de Associação Livre de Palavras e a um questionário sócio demográfico. Os resultados revelaram que as RS sobre a imigração incidiram sobre “dinheiro, trabalho, experiência, interculturalidade, viajar, partir, racismo, solidariedade, oportunidade, mudança, país, economia, superação” e, neste contexto, imigrante surge como sinônimo de “economia, aprendizado, benefício, forte, triste, viajante, lutador”. Conclui-se que as RS possibilitam melhor conhecimento sobre as atividades simbólicas, afetivas e cognitivas dos imigrantes em seu processo de interação social. Espera-se que tais resultados contribuam para os estudos das migrações no âmbito internacional, favorecendo mudanças positivas ao nível das práticas e políticas públicas para estes grupos.
MIGRAÇÕES, CIDADANIA E INTERCULTURALIDADE: PARA UMA ANÁLISE CRÍTICA DO PARADIGMA DOMINANTE NAS CIÊNCIAS SOCIAIS
Authors: Caetano João Carlos Relvão , Paiva Ana Maria Lourenço
Published: November 2018

As primeiras décadas do século XXI caracterizam-se por serem de grande mobilidade de pessoas em todo o mundo, por períodos curtos ou longos, facilitada pelos novos meios de locomoção e comunicação. Entre as razões que levam a que as pessoas se movam de um lugar para outro estão a procura de trabalho e de melhores condições de vida. Mas há também pessoas que se movem por razões económicas e de segurança, correndo sérios riscos de vida, seja por causa dos frágeis meios de transporte que usam, seja por não serem recebidas ou desejadas nos países onde pretendem chegar. Particularmente nos países ocidentais, assiste-se a esforços políticos, cívicos e jurídicos visando a proteção dos muitos milhares de migrantes que aí pretendem chegar, mas que na prática têm fracassado, por falta de vontade ou incapacidade dos Estados de destino de responderem ao que, de acordo com o direito internacional, são obrigações suas. A desresponsabilização dos governos decorre do sentimento dos eleitorados nacionais que se afirmam crescentemente contra a entrada de imigrantes nos seus territórios. Partindo da verificação de que as sociedades ocidentais são sociedades de imigração e precisam de imigrantes para serem prósperas, procura-se perceber por que razão as medidas ditas de integração dos imigrantes têm fracassado e de que modo isso está relacionado não só com o modelo de integração multicultural mas também com a incapacidade das ciências sociais, em particular da sociologia, de conhecerem a realidade da imigração e de darem respostas eficazes que permitam aumentar a coesão social vista como condição para que a imigração, sendo necessária, funcione. Partindo da análise científica do trinómio “migrações”, “cidadania” e “interculturalidade”, os autores desenvolvem e propõem um paradigma alternativo ao paradigma dominante nas ciências sociais nesta matéria, evidenciando a maior importância das razões económicas e sociais (incluindo os direitos políticos dos imigrantes) sobre as razões culturais, como forma de garantir uma vida digna aos imigrantes, futuros cidadãos.
Cancer Immunomics in the Age of Information: Role in Diagnostics and Beyond
Authors: Basharat Zarrin , Yasmin Azra , Masood Nosheen
Published: November 2018

Cancer genome sequencing is useful for diagnosis and personalized treatment. Analysis of the sequencing
data involves integration of computation, statistics and system biology methods. The amalgam of such
methods which help study interaction of cancer cells with immune system, harnessing immune system for cancer
therapy or its prevention through vaccines has led to the foundation of cancer immunomics. It is, therefore, a
combinatorial science which merges diverse techniques from genomics and proteomics for diagnosis and drug
design/treatment. There has been a gradual increase in establishment of cancer immune focused start-ups, research
facilities and pharma giants working on state-of-the-art methods for improving diagnostics, treatment and
prevention or minimizing side effects, applying immunomics. However, we are still far away from making precise,
quick and reliable diagnostic and treatment predictions. We need decision support systems to facilitate diagnosis,
tumor evaluation prediction and assessment of individual profile for making personalized therapy a reality.
The future is centered not only on data management but wise decision aided by artificially intelligent algorithms.
In this review, we provide an overall picture and focus on immune biomarkers and relevant softwares that aid in
diagnostics and analysis of cancer.
The Role of Angiotensin-(1-7)/Mas Axis and Angiotensin Type 2 Receptors in the Central Nervous System in Cardiovascular Disease and Therapeutics: A Riddle to be Solved
Authors: Katsi Vasiliki , Maragkoudakis Spyridon , Marketou Maria , Tsioufis Costas , Parthenakis Fragkiskos , Tousoulis Dimitrios
Published: November 2018

:

In recent years, the Angiotensin-(1-7)/Mas receptor [Ang-(1-7)/Mas] sub-branch of the
Renin-Angiotensin System (RAS) in the brain, and Angiotensin Type 2 Receptors (AT2R), have attracted
scientific interest, as there is evidence that they constitute an essential pathway in cardiovascular
regulation, in health and in disease. By acting centrally, the Ang-(1-7)/Mas axis - that has been termed
‘the axis of good’- can exert blood pressure-lowering effects, while also favourably altering baroreflex
sensitivity and noradrenergic neurotransmission. Thus, research has focused on the possible neuro- and
cardioprotective effects of this pathway in the setting of cardiovascular disease, ultimately aiming to
evaluate the potential for development of novel therapeutic strategies based on its modulation.

:

We summarize the available evidence from experimental studies in this context, aiming to assess current
limits of scientific knowledge relevant to this newly-described ‘player’ in haemodynamic regulation,
that may become a potential therapeutic target.
Microwave-Assisted Synthesis of Chiral Oxime Ethers
Authors: Mehrez Asma , Mtat Dalila , Touati Ridha
Published: November 2018

An efficient and rapid synthesis of a new class of chiral oxime ethers has been achieved via
two-step reaction in which the first step is the reaction of oximes 1a-f with ethyl bromoacetate in the
presence of sodium hydride to give oxime ethers 2a-f which are subsequently, in the second step, reacted
with different commercially available chiral amines under microwave irradiation conditions to
give compounds 3a-l in good to excellent yields. Through this method, we have observed a decrease in
reaction time and excellent yields than the previously described conventional method.
Anti-inflammatory and Antioxidant Activities of the Extracts from Leaves and Stems of Polygonum odoratum Lour
Authors: Chansiw Nittaya , Chotinantakul Kamonnaree , Srichairatanakool Somdet
Published: November 2018

Background: Polygonum odoratum is an indigenous vegetable that has been
used as a favoring agent and also used as a Thai traditional medicine to treat flatulence.

Objective: To analyze active ingredients, total phenolic and total flavonoid contents, antiinflammatory
and antioxidant activities from leaf and stem extracts of P. odoratum.

Methods: Leaves and stems were dried and extracted by using methanol, dichloromethane
and water for obtaining Methanolic Leaf Extract (MLE), Methanolic Stem Extract (MTE),
Dichloromethane Leaf Extract (DLE), Dichloromethane Stem Extract (DTE), Water Leaf
Extract (WLE) and Water Stem Extract (WTE). The extracts were quantified for total phenolic
and total flavonoid contents by spectrophotometry and active compounds were analyzed
by using GC-MS. Antioxidant activity was determined by ABTS and DPPH radicals
scavenging assays. Anti-inflammatory activity was tested by the inhibition of nitric oxide
production in RAW 264.7 macrophage cells induced by lipopolysaccharide.

Results: The DLE exhibited the most potent anti-inflammatory effect by inhibiting nitric
oxide production in a concentration-dependent manner (IC50 = 53.75±0.72 µg/mL). MLE
exhibited strong antioxidant activity and contained the highest concentration of phenolic
compounds (52.59±0.58 mg gallic acid equivalent/g extract) and flavonoid (19.97+0.11
mg quercetin equivalent/g extract). E-15-Heptadecenal and 3, 7, 11, 15-tetramethyl-2-
hexadecen-1-ol were found predominantly in the methanol extracts.

Conclusion: The leaf extract of P. odoratum showed potent anti-inflammatory and antioxidant
activities, mediated by DLE and MLE, respectively.
Effect of Aqueous Extract of Azadirachta indica Leaves on Pharmacokineics and Pharmacodynamics of Glipizide
Authors: Chaudhari Sugandha , Zambad Shitalkumar , Ali Mohammed
Published: November 2018

Background:

Polypharmacy, that is, two (or more) drugs administered together, may cause chemical or pharmacological interactions. Such interactions may alter the effect of either agent, leading to decrease or increase effectiveness of the drugs, which may cause adverse effects. The co-intake of complementary and alternative medicines with therapeutic medicine are supposed to influence pharmacodynamics or pharmacokinetics of the latter.

Objective:

This study was conducted to determine the interaction of glipizide (GZ) with an aqueous extract of Azadirachta indica (AZI) leaves.

Method:

The pharmacokinetics and pharmacodynamics of glipizide was evaluated in High Fat diet (HFD) and streptozotocin induced diabetic Sprague-Dawley rats. Two doses of the AZI leaf extract (250 and 500 mg/kg) were administered alone or in combination with GZ (5 mg/kg) and serum glucose during oral glucose tolerance test, AST, ALT, and ALP levels were as estimated. In vitro CYP3A activity of AZI at 50 µg and 100 µg was assessed using liver microsomes.

Results:

In the glucose tolerance test, AZI and GZ showed a hypoglycemic effect. However, the hypoglycemic effect was lower when AZI was administered in combination with GZ compared with GZ alone. AZI at 100 µg has shown significant potentiation of CYP3A activity. AZI (500 mg/kg) pretreatment significantly decreased AUC and increased Tmax to 8 h.

Conclusion:

This indicated that the pharmacokinetics and pharmacodynamics of GZ altered by AZI might be due to the induction of CYP3A activity. In conclusion, AZI can decrease the bioavailability of GZ, and hence, it should be cautiously used.
Proposed Simple System for Road Traffic Counting
Authors: Alkhatib Ahmad A.A. , Hnaif Adnan , Kanan Tarek
Published: November 2018

Background & Objective:

Traffic congestion is a burning issue in most countries due to
the rapid growth of running vehicles and infrastructures with limited capacity. Congestion can be
solved with Intelligent Transport Systems (ITS) and traffic management. Most traffic management
measurement are aimed to improve the safety and flow of traffic, reduce traffic emissions and utilize
traffic artery capacity more effectively.

Methods:

This paper proposes a new system to collect the required data for traffic management such
as, number of vehicles, time and lane location information; using a cheap infrared sensors and timers.

Conclusion:

The proposed method can take the length of the vehicle into account of traffic statistics
by measuring the car speed.
Design, Optimization and Characterization of Nanostructured Lipid Carriers of Raloxifene Hydrochloride for Transdermal Delivery
Authors: Puro Durga , Athawale Rajani , Pandya Anjali
Published: November 2018

Introduction:

Raloxifene Hydrochloride (RXL), a BCS class II drug, is used for the treatment
of invasive breast cancer and osteoporosis in post menopausal women. Even though the drug is
highly efficient, it shows poor bioavailability of 2% when administered orally. The aim of the study
was to develop, statistically optimize, and characterize Raloxifene Hydrochloride loaded Nanostructured
Lipid Carriers (NLC) for transdermal delivery to overcome the bioavailability issue.

Methods:

The RXL-NLC’s were developed using glyceryl behenate (Compritol® 888 ATO), glyceryl
monostearate (GMS), and capric triglyceride (Miglyol® 810) as solid and liquid lipids, and Polysorbate
80 (Tween 80) and cremophor EL were used as surfactants and co-surfactant. A response surface
methodology was applied for the optimization of NLC, using Box-Behnken experimental design.
Amount of the drug, tween 80 and polyethoxylated castor oil (cremophor EL), each at three levels,
were selected as independent variables, while particle size and polydispersity index were identified as
dependent variables. The optimized batch was characterized for Particle size (79.8 nm±3), Polydispersity
index (0.229±0.05), Zeta potential (-12.3±5) and Entrapment efficiency (79.14%±5). Surface
morphology of the NLC’s were studied using Transmission Electron microscopy (TEM) and the shift
in the endotherm of Differential scanning calorimetry confirmed the entrapment of the drug within
NLC. In vitro drug release studies were performed using dialysis bag (12000-14000 Da) method. The
optimized NLC dispersion was then incorporated into gel and characterized for gel uniformity,
spreadability, pH, viscosity and drug content.

Results:

In vivo skin penetration study was carried out by tape stripping method, which showed increase
in penetration when incorporated into nanogel as compared to plain drug gel.

Conclusion:

Based on the above result it can be concluded that transdermal delivery of NLC’s can be
a superior alternative for orally low bioavailable drugs such as RXL which undergoes rapid first pass
metabolism.
Determinantes de las patentes y otras formas de propiedad intelectual de los estados mexicanos
Authors: Almendarez Hernández Marco Antonio
Published: November 2018

El objetivo del trabajo fue evaluar econométricamente los efectos de indicadores científicos e información tecnológica sobre las patentes, los modelos de utilidad y los diseños industriales. Las funciones de producción de conocimiento teórica y empírica de Griliches (1979) y Hausman et al. (1984), respectivamente, fueron la metodología usada como referencia. Panel para datos de conteo a nivel de entidad federativa fue el tratamiento econométrico empleado para estimar los determinantes de la propiedad intelectual. Los hallazgos revelaron que los estados mexicanos que dedican más esfuerzos a la ciencia y las búsquedas tecnológicas, son más propensos a producir propiedad intelectual.
Estructura de la red de ciudades en la ciudad región Eje cafetero (Colombia)
Authors: Gaviria Ríos Mario Alberto
Published: November 2018

Partiendo de una revisión de la literatura sobre teoría de redes y redes de ciudades, se asume las relaciones de red como el producto de la interacción espacial que se da entre las ciudades, interacciones que se manifiestan a través de distintos flujos de orden material (población, mercancías, capital) e inmaterial (información). Utilizando datos sobre movimientos diarios de pasajeros y con el apoyo del análisis de redes, se identifica la estructura de la red de ciudades de la formación espacial “Ciudad región Eje Cafetero” del centro occidente colombiano, con especial revisión de las condiciones de integración, centralidad y accesibilidad de ese sistema urbano. Estructura de la red de ciudades en la ciudad región Eje cafetero (Colombia)
Обзор мировой практики диагностики смерти мозга
Authors: Kurochka H.V. , Kuibida Yu.O. , Yovenko I.O. , Tsariov O.V.
Published: November 2018

Данная обзорная статья освещает актуальность проблемы создания единых критериев диагностики смерти мозга. Приведены список клинических и инструментальных диагностических критериев, длительность и кратность проведения тестов, состав консилиума, согласно приказу № 821 от 23.09.2013 г. МЗ Украины. Рассмотрены два независимых исследования. Первое исследование, проведенное в 2013 году, выявило значительные отличия в выполнении клинических и подтверждающих тестов. Проведено электронное анкетирование среди специалистов из 28 стран Европы, участвовавших в диагностике смерти мозга. Второе исследование опубликовано Американской ассоциацией неврологии в 2015 году. Оно включало анкетирование специалистов из 120 стран, которые сталкивались с постановкой диагноза смерти мозга. Выявлено: процент стран, имеющих правовые положения и ведомственные протоколы по диагностике смерти мозга; зависимость наличия протоколов, отличия в выполнении тестов от уровня дохода страны и уровня развития трансплантационного звена; отличия в выполнении клинических диагностических тестов (тест апноэ), их длительность и перерывы между ними; частоту и предпочтения в использовании подтверждающих тестов; состав врачебных консилиумов.
Опыт применения налбуфина гидрохлорида в схеме интраоперационной мультимодальной анальгезии как часть протокола ускоренной периоперационной реабилитации в бариатрической хирургии
Authors: Yevsieieva V.V.
Published: November 2018

Целью данного исследования было сравнение анальгетических эффектов налбуфина гидрохлорида и фентанила как основных компонентов в схеме интраоперационной мультимодальной анальгезии у пациентов с морбидным ожирением во время лапароскопических бариатрических вмешательств. Материалы и методы. В исследовании приняли участие 18 пациентов с морбидным ожирением, разделенные на две равнозначные группы (n = 9). В первой группе пациенты в качестве основного анальгетического компонента во время анестезии получали фентанил, во второй группе — налбуфина гидрохлорид. Уровень послеоперационной боли оценивался по визуально-аналоговой шкале (ВАШ) в течение первых послеоперационных суток. Результаты. Уровень послеоперационной боли по ВАШ в первые послеоперационные сутки статистически не отличался между пациентами обеих групп. Выводы. В соответствии с полученными данными налбуфина гидрохлорид является эффективной альтернативой фентанилу в качестве основного анальгетического компонента в схеме мультимодальной интраоперационной анальгезии у пациентов с морбидным ожирением при лапароскопических бариатрических вмешательствах.
Опыт применения имплантационных венозных порт-систем для пациентов, требующих длительной химиотерапии в отделении интенсивной терапии
Authors: Klygunenko O.M. , Baranov I.V. , Ploshchenko Yu.O. , Novikov S.P. , Frolov K.B. , Vasilishin O.V. , Kirilova L.O.
Published: November 2018

В статье описаны осложнения, побочные реакции и проблемы при проведении длительной химиотерапии, а также вариант решения одной из самых распространенных трудностей — обеспечение долгосрочного венозного доступа. По мировым стандартам установка имплантационной венозной порт-системы является рутинной процедурой, однако в Украине такой метод пока на этапе становления. В нашей практике установка венозных порт-систем — это повсе­дневная реальность, и проведение имплантации проходит по соответствующим стандартам в стерильных условиях операционной, с обязательным ультразвуковым контролем и навигацией, соответствующим обследованием и подготовкой пациента к имплантации. За 8 месяцев установлено 32 имплантационные порт-системы, и положительные стороны такого венозного доступа неоспоримы.
Современный подход к образованию врачей: концепция непрерывного медицинского образования и непрерывного профессионального развития
Authors: Klygunenko O.M. , Кravets О.V. , Ploshchenko Yu.O. , Sedinkin V.A. , Khalimonchyk V.V.
Published: November 2018

По современным требованиям медицинское образование представляет собой неразрывность и преемственность трех этапов. Первые два — академические, или традиционные, это обучение в высшей школе и последипломное образование. Третий компонент медицинского образования представляет собой непрерывное медицинское образование. По результатам систематизированных анализов получение только академического образования (уровень 3) не приводит к достижению клинических компетентности (уровень 4) и эффективности (уровень 5), в то время как именно качественное овладение последними позволяет улучшить здоровье пациентов (уровень 6). Кафедра анестезиологии, интенсивной терапии и медицины неотложных состояний ГУ «Днепропетровская медицинская академия» МЗ Украины на протяжении 30 лет осуществляет последипломное обучение врачей-интернов и врачей — специалистов по специальностям «анестезиология» и «детская анестезиология» для Днепропетровского региона и всей Украины. Мы продолжаем проводить обучение по структурированным программам, аккредитованным МЗ Украины, одновременно проводя узкотематические курсы, учитывающие потребности здравоохранения региона. Для повышения качества и эффективности обучения мы используем гибридно-смешанное обучение (у постели больного, лекции-дискуссии, обсуждение анонимных клинических случаев в закрытых группах социальных сетей, применение ролевых игр, симуляторов и тренажеров с компьютерными программами виртуальной реальности). Сочетание нами двух образовательных систем (непрерывное медицинское образование/непрерывное профессиональное развитие) позволило поднять результативность обучения с 4-го уровня (компетентность) до 6-го уровня (здоровье пациента) знаний в пирамиде непрерывного медицинского образования, что подтвердилось повышением эффективности аккредитации врачей-анестезиологов, проводимой 1 раз в 5 лет МЗ Украины на регионарном и национальном уровнях.
Медична допомога хворим на ішемічний інсульт у перші години розвитку захворювання
Authors: Gosteva G.V. , Kovalenko O.Ye.
Published: November 2018

Мета. Ретроспективна порівняльна оцінка клінічних результатів лікування хворих у гострий період ішемічного інсульту (інфаркту мозку) при застосуванні тромболізису та стандартної терапії для подальшої оптимізації надання медичної допомоги на різних рівнях. Матеріали та методи. Проаналізовано 90 історій хвороб пацієнтів з ішемічним інсультом. Серед усієї кількості хворих виділено дві основні групи: 1­ша — хворі із стандартним лікуванням (група порівняння); 2­га — пацієнти після тромболітичної терапії (альтеплазе). Проаналізовано деякі чинники, що впливали на вибір лікувальної тактики, проведено клініко­анамнестичну порівняльну оцінку результатів лікування хворих за шкалою NIHSS у гострий період ішемічного інсульту. Результати. Доведено, що після проведення тромболітичної терапії скорочуються строки перебування хворих у стаціонарі внаслідок підвищення рівня відновлення втрачених функцій, а кількість хворих, які потребують постійного стороннього догляду, в півтора рази менша, ніж при звичайному консервативному лікуванні. Висновки. Ранні госпіталізація та початок лікування позитивно впливають на відновлення функцій хворих як при проведенні тромболізису, так і при стандартному лікуванні. Аналіз перебігу захворювання, результатів лікування дає можливість визнати тромболітичну терапію ефективним і перспективним методом лікування інфаркту мозку, якісне забезпечення якого є неможливим без кваліфікованої роботи спеціалістів різних ланок медичної допомоги.
Клінічний досвід використання рослинного засобу Глюцемедін у комплексному лікуванні хворих на цукровий діабет 2-го типу
Authors: Shebaldova K.O. , Komisarenko Yu.I.
Published: November 2018

Актуальність. Сучасним завданням лікування пацієнтів із цукровим діабетом 2-го типу й дисліпопротеїнемією є аналіз ефективності поєднання стандартних цукрознижувальних засобів з фітотерапевтичними препаратами, але інформація про особливості їх використання потребує уточнення. Мета: оцінити вплив лікування фіксованою комбінацією екстракту листя джимнеми, листя банаби й гіркої дині в поєднанні з препаратами сульфонілсечовини й метформіну на динаміку клінічного стану, вуглеводний і ліпідний обміни в пацієнтів із цукровим діабетом 2-го типу. Матеріали та методи. У дослідженні брали участь 40 пацієнтів (з них 16 чоловіків) віком 61,7 ± 7,8 року із цукровим діабетом 2-го типу. В усіх хворих до початку лікування й через 2 місяці виконували загальний аналіз крові, визначали рівень глікованого гемоглобіну, креатиніну, сечовини, білірубіну, аланінамінотрансферази, аспартатамінотрансферази, холестерину, ліпопротеїнів високої та низької щільності, тригліцеридів, глюкози. Усі пацієнти відповідно до базової цукрознижувальної терапії були поділені на чотири групи. 1-ша група отримувала метформін (n = 6); 2-га група — метформін і гліклазид (n = 10); 3-тя група — метформін і глімепірид (n = 14). Пацієнтам дозу цукрознижувальних препаратів не змінювали під час усього дослідження, додатково був призначений Глюцемедінпо 1 капсулі тричі на день протягом 2 місяців. У 4-й (контрольній) групі (n = 10) стандартну цукрознижувальну терапію не модифікували. Результати. Включення в лікувальні заходи прийому Глюцемедінупривело до статистично значущого зниження рівня глікемії, глікованого гемоглобіну, тригліцеридів і збільшення рівня ліпопротеїнів високої щільності й не вплинуло на концентрацію загального холестерину й ліпопротеїнів низької щільності. Висновки. Отримані результати дозволяють вважати, що ефективність комбінованої терапії Глюцемедіном і пероральними цукрознижувальними засобами є наслідком взаємної потенціюючої дії цих фармакологічних агентів на досліджувані показники, що обґрунтовує доцільність її використання в лікуванні хворих на цукровий діабет 2-го типу.
Funcionalismo translinguístico e cognição: relações entre corpo e gramática das línguas
Authors: Silva Leosmar Aparecido da , Casseb-Galvão Vânia Cristina
Published: November 2018

Este artigo tem o objetivo de fazer um estudo funcional-tipológico de alguns sistemas linguísticos para verificar como esses sistemas utilizam partes do corpo humano em sua morfossintaxe. Esse objetivo está alinhado à hipótese da mente corporificada da Linguística Cognitiva, que considera que as operações mentais e linguísticas estão ancoradas no corpo humano. Analisando o sistema dêitico, as construções indicativas de movimento e o sistema de classificadores de algumas línguas, observou-se que palavras e morfemas que indicam partes do corpo humano integram a gramática dessas línguas. Trabalhos dessa natureza, além de contribuírem para se ter acesso a dados de línguas faladas por minorias, contribuem para desconstruir teses racionalistas que dicotomizam mente e corpo.
O estatuto categorial dos subordinadores adverbiais complexos numa visão cognitivo-funcional da linguagem
Authors: Neves Maria Helena De Moura , Coneglian André Vinícius Lopes
Published: November 2018

Este artigo discute o estatuto categorial dos subordinadores adverbiais complexos, com foco nos causais e nos concessivos, a partir da consideração de fatores de ordem funcional bem como de fatores de ordem cognitiva. São oferecidas duas amostras de análise, para dois subordinadores adverbiais complexos, um, causal, visto que, e o outro, concessivo, se bem que. A direção de análise é justamente a de explicitar a inter-relação de propriedades funcionais com propriedades cognitivas dos subordinadores adverbiais complexos, mediante a verificação de como se sustentam as relações gramaticais nas construções adverbiais causais e concessivas no uso linguístico.
Refleksija par vērtībām tagadnes kontekstā
Authors: Sīle Vija , Sīlis Vents
Published: November 2018

Ja vērtības netiek praktizētas un iemiesotas cilvēka, sabiedrības un valstu attiecībās, tās ir deklaratīvas, tukšas, reizēm pat bīstamas un kļūst par manipulācijas instrumentu politiskajās cīņās
Os relevos da memória
Authors: Santa Cruz Lucia
Published: November 2018

Este artigo aborda projetos memorialísticos desenvolvidos por meios de comunicação. Iniciativas como Memória Globo, Memória O Globo, Acervo Estadão, se mostram, simultaneamente, movimentos de valorização da memória e instrumentos de produção de novas versões sobre fatos passados, envolvendo ou não os veículos jornalísticos. Além de funcionarem como resgate e preservação da história dos veículos, reforçando ou estabelecendo uma determinada identidade, são o que Pierre Nora chamou de “lugares de memória” -  espaços físicos ou não onde indivíduos e grupos sociais podem ancorar sua memória, face ao fenômeno da aceleração da história que torna o presente cada vez mais volátil. Ao assumirem esta configuração, colocam em questão aspectos constituintes do jornalismo, tais como critérios de atualidade e novidade, além de fomentarem uma rediscussão dos valores de noticiabilidade.
A normalização do golpe: o esvaziamento da política na cobertura jornalística do “impeachment” de Dilma Rousseff
Authors: Prudencio Kelly , Rizzotto Carla , Sampaio Rafael Cardoso
Published: November 2018

O artigo apresenta resultados de uma pesquisa sobre a cobertura jornalística do processo de impeachment da presidenta Dilma Rousseff, entre dezembro de 2015, quando foi aberto o processo na Câmara dos Deputados, e agosto de 2016, quando ela foi afastada definitivamente pelo Senado Federal. Foram analisadas 2.202 notícias publicadas pelos jornais O Globo, Folha de S. Paulo e O Estado de S. Paulo pela perspectiva metodológica do enquadramento multimodal, que considera os aspectos textuais, visuais e narrativos das notícias. Os dados permitem verificar que houve uma orientação editorial ligeiramente superior para uma posição pró-impeachment, mas isso só pode ser afirmado na junção dos três modos do enquadramento, uma vez que o texto das notícias seguiu o padrão de cobertura pragmática. Argumentamos que esse padrão acabou por normalizar o impeachment como processo legítimo, despolitizando-o e apagando os aspectos que o evidenciam como golpe parlamentar.
Saliência na conservação de /d/ no segmento /ndo/: efeitos sociais e estilísticos
Authors: Freitag Raquel Meister Ko , Cardoso Paloma Batista , Pinheiro Bruno Felipe Marques
Published: November 2018

A consciência social é uma propriedade importante da mudança linguística e o que faz com que uma variável seja sensível ou não à avaliação em uma comunidade pode estar atrelado ao seu grau de saliência. A fim de observar a relação entre saliência e consciência social, neste texto, discutimos efeitos subjacentes desses conceitos na perspectiva da produção linguística, considerando delineamento dos condicionamentos sociais, estilísticos e estruturais na conservação de /d/ no segmento /ndo/ na fala de Aracaju/SE, a partir do que tem sido descrito em diferentes variedades do Português Brasileiro. A amostra faz parte do Banco de Dados Falares Sergipanos, composta por 20 entrevistas sociolinguísticas, estratificadas quanto ao sexo/gênero e escolaridade (ensino médio e superior). Os fatores estruturais não se mostraram estatisticamente significativos, sinalizando para a necessidade de ampliação da amostra. Os resultados sugerem que a variável na fala de Aracaju se comporta, do ponto de vista da produção, como um marcador, ou indexador de segunda ordem, com base no delineamento do perfil social e estilístico associado à conservação de /d/ em segmentos /ndo/: mulheres, ensino superior, assuntos de maior formalidade e em trechos opinativos.
Para conhecer: Semântica, de Ana Quadros Gomes e Luciana Sanchez Mendes
Authors: Rosa-Silva Fernanda
Published: November 2018

Resenha do livro:GOMES, A. Q.; SANCHEZ-MENDES, L. Para conhecer: Semântica. São Paulo: Contexto, 2018.
IOT-BASED EARTHQUAKE WARNING SYSTEM DEVELOPMENT AND EVALUATION
Authors: KARACI Abdulkadir
Published: November 2018

In this study a low cost earthquake warning system has been developed that will detect non-destructive foreshocks. The developed system is an IOT application where objects communicate with each other. Arduino mega was used as the micro controller in the system. The purpose of developing earthquake warning system is to announce the information about the beginning and end of the earthquake at the instant of earthquake as a tweet in tweeter and to give audible alert for the persons in the environment. IMU and piezo vibration sensors were used to detect the vibrations at the moment of the earthquake. Also, ESP8266 Wi-Fi module was included in the system for the system to connect to the internet. The system evaluates the data from IMU and vibration sensors to detect the earthquake. For IMU sensor, data is evaluated in two axes; namely x and y. ıf the change in x- or y-axis is equal to or greater than 10 or the data from vibration sensor is greater than 694 then the earthquake warning system is triggered. As a result of this triggering the system connects to internet via Wi-Fi module, a tweet is sent to inform that the earthquake has started and audible alert is given locally. ThingSpeak IoT analytics platform is used for the system top send tweet. When the system is triggered, necessary data is sent to the ThingSpeak platform and tweet is sent through this platform. Also, system’s sensitivity threshold values can be changed and adjusted. According to the results of real-time operation, it has been determined that the developed system can detect the earthquake successfully and sensitively and provide audible alert and send tweet for warning.
On the 3-parameter spatial motions in Lorentzian 3-space
Authors: Yıldırım Handan , Kuruoğlu Nuri
Published: November 2018

In this paper, we obtain the formulas of the volume element and the volume of
the region which is determined in the fixed space by any fixed point of the
moving space under the 3-parameter spatial motions in Lorentzian 3-space L3.
Moreover, taking into account these formulas, we give Holditch-Type Theorems
and some corollaries in Lorentzian sense.
Pseudo almost automorphic mild solution of nonautonomous stochastic functional integro-differential equations
Authors: Xia Zhinan , Wang Dingjiang
Published: November 2018

In this paper, we propose a new class of stochastic process called
(?,?)-pseudo almost automorphic in p-mean, which generalize in a natural
fashion the concept of square-mean almost automorphy and its various
extensions. As application, we establish the existence, uniqueness
of(?,?)-pseudo almost automorphic in p-distribution mild solution to
nonautonomous stochastic functional integro-differential equations. Finally,
an example is given to illustrate the significance of the main findings.
Skew-rank of an oriented graph in terms of the rank and dimension of cycle space of its underlying graph
Authors: Lu Yong , Wang Ligong , Zhou Qiannan
Published: November 2018

Let G? be an oriented graph and S(G?) be its skew-adjacency matrix, where G
is called the underlying graph of G?. The skew-rank of G?, denoted by
sr(G?), is the rank of S(G?). Denote by d(G) = |E(G)|-|V(G)| + ?(G) the
dimension of cycle spaces of G, where |E(G)|, |V(G)| and ?(G) are the edge
number, vertex number and the number of connected components of G,
respectively. Recently, Wong, Ma and Tian [European J. Combin. 54 (2016)
76-86] proved that sr(G?) ? r(G) + 2d(G) for an oriented graph G?, where
r(G) is the rank of the adjacency matrix of G, and characterized the graphs
whose skew-rank attain the upper bound. However, the problem of the lower
bound of sr(G?) of an oriented graph G? in terms of r(G) and d(G) of its
underlying graph G is left open till now. In this paper, we prove that
sr(G?) ? r(G)-2d(G) for an oriented graph G? and characterize the graphs
whose skew-rank attain the lower bound.
Some general coefficient estimates for a new class of analytic and bi-univalent functions defined by a linear combination
Authors: Srivastava H.M. , Sakar Müge , Özlem Güney
Published: November 2018

In the present paper, we introduce and investigate a new class of analytic
and bi-univalent functions f (z) in the open unit disk U. For this purpose,
we make use of a linear combination of the following three functions: f(z)/z,
f'(z) and z f''(z) for a function belonging to the normalized univalent
function class S. By applying the technique involving the Faber polynomials,
we determine estimates for the general Taylor-Maclaurin coefficient of
functions belonging to the analytic and bi-univalent function class which we
have introduced here. We also demonstrate the not-too-obvious behaviour of
the first two Taylor-Maclaurin coefficients of such functions.
On the average of the eccentricities of a graph
Authors: Das Kinkar , Xu Kexiang , Li Xia , Liu Haiqiong
Published: November 2018

Let G = (V; E) be a simple connected graph of order n with m edges. Also let
eG(vi) be the eccentricity of a vertex vi in G. We can assume that eG(v1)
eG(v2) ? ... ? eG(vn-1) ? eG(vn). The average eccentricity of a graph G
is the mean value of eccentricities of vertices of G, avec(G) = 1/n ?n,i=1
eG(vi). Let ? = ?G be the largest positive integer such that eG(vG ) ?
avec(G). In this paper, we study the value of G of a graph G. For any tree T
of order n, we prove that 2 ? ?T ? n - 1 and we characterize the extremal
graphs. Moreover, we prove that for any graph G of order n,2 ? ?G ? n and we
characterize the extremal graphs. Finally some Nordhaus-Gaddum type results
are obtained on ?G of general graphs G.
Complete moment convergence for Sung’s type weighted sums of ρ*-mixing random variables
Authors: Li Wei , Chen Pingyan , Sung Soo
Published: November 2018

In this paper, the authors study a complete moment convergence result for
Sung?s type weighted sums of ?*-mixing random variables. This result extends
and improves the corresponding theorem of Sung [S.H. Sung, Complete
convergence for weighted sums of ?*-mixing random variables, Discrete Dyn.
Nat. Soc. 2010 (2010), Article ID 630608, 13 pages].
Antifungal activity of chitosan and its quaternized derivative in gel form and as an edible coating on cut cherry tomatoes
Authors: da Silva , Bitencourt Tamires , Saltoratto Ana , Seleghim Mirna , Assis Odílio
Published: November 2018

The antifungal activities of medium molecular weight chitosan and its
hydrosoluble derivative salt N,N,N-trimethylchitosan were examined as both
gel and as a solid protective coating against three common food spoilage
fungi (Penicilliumsp., wild Aspergillussp. and one standard strain of
Aspergillusflavus). The salt derivative is characterized by having permanent
positive charges and is expected to have a higher antimicrobial activity
than commercial chitosan. In gel form, the minimum inhibitory concentration
(MIC) resulted in the same value for both polymers against all tested fungi
(> 2.0 gl-1). The derivative presented a significant fungistatic action
against the Penicillium strain within the concentration range of 0.2 to 0.6
gl-1. When applied as protective coatings on freshly cut cherry tomatoes,
the commercial chitosan appeared to be more effective in forming stable
films and preventing fungal infestation than its derivative. Less than
20?25% of samples were infected after one week of incubation when compared
to control (uncoated) and chitosan treated samples.
Preconcentration of ultra-traces of Cu(II) in water samples using SBA-15 sorbent modified with a thiocarbohydrazide ligand prior to determination by flame atomic absorption spectrometry
Authors: Payehghadr Mahmood , Qezelje Haghgoo , Nourifard Farzaneh , Attaran Abdolmohammad , Kalhor Mehdi
Published: November 2018

A simple, reliable and rapid method for the extraction of ultra-trace copper(II) using nanoporous SBA-15 sorbent modified with a thiocarbohydrazide ligand, and determination by flame atomic absorption spectrometry is presented. The optimum parameters of the method were obtained as pH of aqueous solution 5, sorbent amount 2 mg, stirring time 20 min and 0.4 M HCl solution as the eluent solvent. This method has a breakthrough volume greater than 1500 mL with a concentration factor of more than 300, linear range 0.8?2500.0 ?g L-1, limit of detection 0.253 ?g L-1 and limit of quantification 0.844 ?g L-1 for copper(II). The capacity of 2 mg of modified SBA-15was found to be 123.00?0.04 mg g-1. Standard deviations were 3.3, 2.3 and 2.1 % for 1, 2 and 4 ?g mL-1, respectively (n = 5). This method was successfully applied for the determination of copper(II) in different real samples, especially in the food samples.
Lärarstudenter som aktörer i interaktiv observation och handledning
Authors: Wennergren Ann-Christine , Thornberg Fredrik , Bjørndal Cato , Mathisen Petter
Published: November 2018

Syftet med denna artikel är att bidra med kunskap om hur digitala redskap kan påverka lärarstudenters deltagande i handledningsprocessen. Trots att lärarstudenter och handledare ofta befinner sig i digitala klassrumsmiljöer används digitala redskap endast i begränsad omfattning under handledningsprocessen. Med utgångspunkt i Wengers teori om lärande i en praktikgemenskap har lärarstudenter och handledare arbetat med stöd av digitala observationsunderlag.
Processen har studerats på fyra övningsskolor. Information om studenternas erfarenheter av handledningen har samlats in via enkäter och fokusgruppsamtal. Resultatet visar att det är fyra moment som påverkat studenters deltaganden i handledningsprocessen. Studenter 1) delar sin planering digitalt inför undervisning, 2) skapar digitala observationsunderlag från undervisning, 3) använder digitala observationsunderlag för att förbereda handledningssamtal, 4) väljer aspekter från digitala observationsunderlag för bearbetning i handledningssamtal.
Resultatet ger också signaler om två kritiska moment som särskilt underlättat deltagande i handledningsprocessen: dels bearbetningen av planering före undervisning, dels bearbetningen av observation före handledning. Det visar att studenters och handledares gemensamma deltagande och ansvar för handledningsprocessen påverkar både form, innehåll och utfall.
The application of waste marble as coarse aggregate in concrete production
Authors: Chang Kok Yung , Kwan Wai Hoe , Kua Hui Bun
Published: November 2018

The massive growth of construction industry especially in the developing countries results in extensive quarrying activities which ultimately would lead to the depletion of natural resources. Apart from extensive extraction of the natural granite from the earth for concrete production, marble production industry is also majorly contributing to the quarrying activities. In addition, high volume of waste is generated by the marble production industry as 70% of marble is wasted during the production such as quarrying, cutting, processing and others which is environmental unfriendly. In a way to achieve sustainable construction, the present study is to utilise the waste marble in replacing the coarse aggregate in concrete production. The engineering performance including workability, compressive strength, ultrasonic pulse velocity (UPV) and chloride penetration were analysed. The raw waste marble obtained from the industry were crushed and sieved into maximum size 20 mm and used to replace the coarse aggregate at the level of 20%, 40%, 60%, 80% and 100% respectively. Results show that 60% of the replacement level has yield to optimum result by achieving the highest compressive strength and UPV at approximate 5% higher than the control. Meanwhile, the effect on chloride penetration resistance is more significant, i.e. approximate 19% better than the control. However, increasing the replacement level of waste marble has no significant effect on workability, although an increasing trend was observed.
Etat des connaissances et conservation de flore endemique dans la region d’Oran (Algerie occidentale)
Authors: Mansouri Sihem , Miara Mohamed Djamel , Hadjadj-Aoul Seghir
Published: November 2018

ResumeCette étude est une première exploration régionale visant la recherche des plantes endémiques de la région d›Oran en vue d›une éventuelle évaluation de leur état de conservation. Les recherches se sont basées essentiellement sur les 124 relevés phytoecologiques réalisés à travers les secteurs O1 et O2 ainsi que certains sorties ciblant les stations de présence des espèces endémiques signalées pour la région d›Oran dans la littérature. Ces recherches de terrain ont conduit à l›identification de 17 taxons endémiques dont certains sont très rares comme Brassic aspinescens et Helianthemum maritimum. D’autres espèces ayant été ciblées par les recherches n’ont pas été retrouvées ce qui renforce l’hypothèse de disparition de certaines d’entre elles. En plus de cette première liste des endémiques réellement observés dans la région depuis l’indépendance du pays, les données sur leurs aspects chorologiques, écologiques et biogéographiques sont exposées et discutés. Mots clés: Endémique, flore, chorologie, conservation, inventaire, Oran, rare. AbstractThis study is a first regional exploration for plants research of the Oran region for a possible evaluation for their conditions of conservation. The research were basically based on 124 phytoecological records carried out across the sectors O1 and O2 as well as some data targeting endemic species presence stations reported for the region of Oran in the literature. This field searches led to the identification of 17 endemic taxa some of which are very rare like Brassica spinescens and Helianthemum maritimum. Other targeted species were not found, which reinforces the hypothesis of the disappearance of some of them. In addition to this first list of endemics actually observed in the region since the independence of the country, the data on their chorological, ecological and phytobiogeographical aspects are exposed and discussed. Key words: Endemics, flora, chorology, conservation, inventory, Oran, rare.
An Optimized Snowmelt Lysimeter System for Monitoring Melt Rates and Collecting Samples for Stable Water Isotope Analysis
Authors: Rücker Andrea , Zappa Massimiliano , Boss Stefan , Freyberg Jana von
Published: November 2018

The contribution of snow meltwater to catchment streamflow can be quantified through hydrograph separation analyses for which stable water isotopes (18O, 2H) are used as environmental tracers. For this, the spatial and temporal variability of the isotopic composition of meltwater needs to be captured by the sampling method. This study compares an optimized snowmelt lysimeter system and an unheated precipitation collector with focus on their ability to capture snowmelt rates and the isotopic composition of snowmelt. The snowmelt lysimeter system consists of three individual unenclosed lysimeters at ground level with a surface of 0.14 m2 each. The unheated precipitation collector consists of a 30 cm-long, extended funnel with its orifice at 2.3 m above ground. Daily snowmelt samples were collected with both systems during two snowfall-snowmelt periods in 2016. The snowmelt lysimeter system provided more accurate measurements of natural melt rates and allowed for capturing the small-scale variability of snowmelt process at the plot scale, such as lateral meltwater flow from the surrounding snowpack. Because of the restricted volume of the extended funnel, daily melt rates from the unheated precipitation collector were up to 43% smaller compared to the snowmelt lysimeter system. Overall, both snowmelt collection methods captured the general temporal evolution of the isotopic signature in snowmelt.