bluuebunny/crossref_metadata_2025 huggingface dataset:
СМИСАОНОСНИ ПРАВАЦ ЉУДСКОГ ХОДА: ИЗАЗОВИ ВРЕДНОСНОГ ОРИЈЕНТИСАЊА И ХОЛИСТИЧКО РАЗУМЕВАЊЕ ЉУДСКЕ ДОБРОБИТИ
Authors: Jakovljević Dragan
Published: December 2021

Unter Anknüpfung an J. Mittelstraß versucht der Verfasser die Frage zu klären, Wohin der Mensch (dh. die Menschheit) geht, bzw. wohin es eigentlich für ihn wünschenswert wäre, zu gehen. Nach einer Bestimmung des Orientierungsbegriffes selbst, werden die Thesen von M. Markowitsch zur krisenhaften gegenwärtigen Lage der gesellschaftlichen Moral diskutiert, wobei seinen kritischen Befunden nur teilweise zugestimmt wird. Daran anschließend, werden die Thesen von M. Kangrga und M. Horkheimer bezüglich der Globalisierung als eines prägenden Phänomens unserer Zeit erötert. Im weiteren Verlauf seiner Ausführungen geht der Verfasser dazu über, seine Ablehnung des Anthropozentrismus sowie des Speziesimus darzulegen, wobei auch die Interessen von anderen Lebewesengattungen sowie der natürlichen Umwelt explizit berücksicht werden. Letztlich wird daran auch eine dazu passende Sichtsweise des Sinnes der menschlichen Existenz und ihrer Erfüllung angeschloßen. In den abschließenden Betrachtungen wird  zunächst  die verbreitete einfache Vorstellung vom anhaltenden Fortschritt innerhalb der Zivilisationsgeschichte zurückgewiesen, unter dem Hinweis auch auf die These des Kulturpessimismus, die den besorgniserregenden Untergang von Kulturwerten feststellt. Am Ende seiner Ausführungen sieht der Verfasser dann die grundsätzliche Möglichkeit eines ausgedehnten Übereinkommens bezüglich der Wahl vom werthaften, holystisch gesinnten ökologisch-biozentrischen Rahmen zur Lebensführung in den menschlichen Gemeinschaften kommender Zeit  vor – auch noch auf der intekulturellen Ebene.
Cell-free supernatants of lactobacilli inhibit methicilin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus and carbapenem-resistant Klebsiella strains
Authors: KALAYCI YÜKSEK Fatma , GÜMÜŞ Defne , BAYIRLI TURAN Derya Bayırlı Turan , NAKİPOĞLU Yaşar , ADALETİ Rıza , KÜÇÜKER A. Mine
Published: December 2021

Aim: Antibiotic resistance is a major health problem. Recently, probiotics are used in the field of alternative/supportive medicine. Thus, in this study, we aimed to evaluate the in vitro inhibitory effects of four different cell-free supernatants (CFSs) of lactobacilli species (L. fermentum, L. plantarum, L. acidophilus and L. rhamnosus) on clinically isolated Methicilin-resistant Staphylococcus aureus (MRSA) strains, Vancomycin-resistant Enterococcus (VRE) strains, and Carbapenem-resistant Klebsiella (CRK) strains. Materials and Methods: Lactobacillus strains were grown in de Man Rogosa Sharpe broth; after filtration, CFSs were diluted to obtain 25, 50, and 100% concentrations. Pathogen bacteria were grown in tryptic soy broth with and without CFSs in a micro-plate. The bacterial growths were measured using spectrophotometric method after four hours of incubation at 37°C. One-way ANOVA followed by Dunnett’s multiple comparisons and Kruskal-Wallis test were used for statistical analyses. Results: All tested CFSs at all concentrations were found to inhibit growth of MRSA, VRE, CRK strains; the results were found statistically significant (p<0.0001). At 50% concentrations, all CFSs were found to be most effective on MRSA growth. The CFSs of L.fermentum, L.acidophilus and L.plantarum were found to be most inhibitory at 50% concentration on VRE growth. 50% diluted CFSs of L.fermentum and L.plantarum were found to be effective on growth of CRK. All results were found statistically significant (p<0.0001). Conclusion: In our study, our results support that CFSs of lactobacilli strains inhibit growth of multi-drug resistant bacteria. Their inhibitory effects were dependent on microorganisms and CFS concentrations.
Plevral sıvı kolesterol düzeyinin eksüda ve transüda ayırımındaki rolü
Authors: ERMİN Sinem , KAYIKÇI Hazal , BATUM Özgür , YILMAZ Ufuk
Published: December 2021

Amaç: Plevral sıvıların tanısında, transüda (T)–eksüda (E) ayrımının yapılması önemlidir. Bu çalışmanın amacı, Light kriterleri ile plevral sıvı kolesterol düzeyini içeren tekli, ikili ve üçlü testlerin, T-E ayırımındaki duyarlılık ve özgüllüğünü belirlemektir.

Gereç ve Yöntem: Çalışmaya plevral sıvı nedeniyle başvuran 145 hasta dâhil edildi. Plevral sıvı kolesterol düzeyi (PSKD) ≥45 mg/dL (tekli test); PSKD ≥45 mg/dL veya plevral sıvı LDH düzeyi >kan normal LDH’sının %45 (ikili test); plevral sıvı protein >2,9 g/dL, PSKD ≥45 mg/dL, plevral sıvı LDH düzeyi >kan normal LDH’sının %45 (üçlü test) olarak tanımlandı. Kesin tanıya uygun beklenen plevral sıvı tipi altın standart olarak değerlendirmeye alındı.

Bulgular: Çalışmaya alınan 139 hastada, kesin tanıya uygun beklenen plevral sıvı tipi olguların %81’inde eksüda; %19’unda transüda olarak belirlendi. Eksüdatif plevral sıvıyı saptamada, tekli testin kesin tanıya uygun beklenen plevral sıvı tipi ile karşılaştırılmasında iki grup arasında sınırda anlamlılık saptandı (p=0.05). İkili ve üçlü test değerlendirmelerinde ise iki grup arasında istatistiki anlamlı fark saptandı (p
Do physical therapy modalities have additional benefit over exercise therapy in the management of Ankylosing Spondylitis? A randomized controlled trial
Authors: DONMEZ Ulku , OZTURK Cihat , CİNAR Ece , KOCANAOGULLARİ Hayriye , GUCENMEZ Sercan , HEPGULER Simin
Published: December 2021

Aim: The aim of this study was to evaluate the effectiveness of microwave therapy and global postural reeducation (GPR) exercises on disease activity, pain, quality of life and functional status in patients with ankylosing spondylitis (AS).

Materials and Methods: 77 patients diagnosed with AS were included in the study. First group (n: 25) was treated with global postural reeducation exercises 5 days a week, for 3 weeks. Patients in the second group (n: 26), in addition to GPR, were treated with microwave therapy before each exercise session to warm lumbar paraspinal muscles. Third group (n: 26) consisted of controls. Subjects were evaluated at baseline, on the third week, third and six months.

Results: In the first group, improvement in all parameters was found to be significant (p
Acil serviste tıbbi sosyal hizmet müdahalesi gereksinimi olan hastaların retrospektif değerlendirilmesi
Authors: YALÇINLI Sercan , KARBEK AKARCA Funda , YERDELEN Berna
Published: December 2021

Amaç: Bu çalışmada, bir üçüncü basamak üniversite hastanesi acil servisine başvuran ve sosyal hizmet değerlendirmesi yapılan hastaların özellikleri araştırıldı.

Gereç ve Yöntem: Acil servise 2012-2019 yılları arasında başvuran ve sosyal hizmet değerlendirmesi yapılan hastalar çalışmaya dahil edildi. Hasta dosya kayıtları retrospektif olarak taranarak, hastaların demografik ve klinik özellikleri araştırıldı.

Bulgular: Çalışma popülasyonu 243 hastadan oluştu. Ortalama yaş 55,6 ± 20,3 olarak belirlendi ve hastaların %65,8’i erkekti (n:160). Sosyal hizmet değerlendirmesinin talep edilmesinin en yaygın nedenleri, hastaların barınma (%36,2), ulaşım (%30,0) ve rehberlik hizmetleri (%18,9) ihtiyaçlarıydı. Sosyal hizmet birimi tarafından hastalara en sık; danışmanlık (%28,4), hasta yakınlarına ulaşma (%23), Aile, Çalışma ve Sosyal Hizmetler İl Müdürlüğü ile temasa geçilmesi (%20,6), psiko-sosyal görüşme (%15,2) şeklinde hizmet verildiği belirlendi. Hastaların sosyal hizmet birimi değerlendirmesi sonrası % 35,7’sinin kuruma yönlendirildiği (n:84), %23,4’ünün yakınlarına teslim edildiği (n:55), %16,6’sının da kuruma yerleştirildiği (n:39) saptandı.

Sonuç: Acil servislerde sosyal hizmet uzmanı değerlendirmesine ihtiyaç duyulur. Barınma ve ulaşım sorunları en sık sosyal hizmet desteği istenme nedenleridir. Acil servis çalışanlarının sosyal hizmet uygulamalarının kapsamı hakkında farkındalıklarının artırılması gerekir. Acil servislerde tam zamanlı sosyal hizmet görevlilerinin daha fazla hastaya temas edebilmek için bulunması gereklidir.
A rare cause of hypercalcemia: two cases of parathyroid adenoma
Authors: HEPOKUR Merve Nur , ÖZKÖK Meltem , ÇAĞLAR OSKAYLI Meltem , ÖZEMİR İbrahim Ali , ÖNDER Aşan
Published: December 2021

Hypercalcemia is a rare but serious metabolic condition that may lead to end-organ damage. Primary hyperparathyroidism is a rare disease in children and adolescents and parathyroid adenoma is the most common cause. Most of patients are clinically symptomatic and may present signs or symptoms of hypercalcemia. The aim of this report is to describe two case of hypercalcemia due to parathyroid adenoma presenting with different clinical findings.

14 years old male patient with abdominal pain, vomiting and nausea were diagnosed with acute pancreatitis. His laboratory findings were elevated amylase and lipase levels, hyperglycemia, hypercalcemia and hyperparathyroidism. Parathyroid scintigraphy showed the presence of an adenoma. Normocalcemia was provided with pamidronate and hyperglycemia was treated with insulin. Adenoma excision was performed after acute pancreatitis was recovered with replacement therapy. After the surgery, diabetes mellitus persisted and he had a hungry bone syndrome.

Other patient was a 12-year-old male patient presented with complaints of anorexia, weakness, constipation and nausea. He had hypercalcemia, hypophosphatemia and hyperparathyroidism. Parathyroid adenoma was detected with parathyroid scintigraphy. Adenoma excision was performed and postoperatively he had a hungry bone syndrome.

Hypercalcemia associated with primary hyperparathyroidism is rare but generally symptomatic in children and adolescents. It should be kept in mind in the differential diagnosis of hypercalcemia and patients should be protected from complications and permanent damage.
Analisis Permainan Visic (Visual Spatial Of Rubic) dalam Mengembangkan Kecerdasan Visual Spasial Anak Usia 4-5 Tahun
Authors: Tyas Indah Suryaning , Yuliati Nanik , Aisiyah Laily Nur
Published: December 2021

Visual Spasial merupakan salah satu kecerdasan yang memungkinkan anak memahami informasi dalam bentuk gambar lebih baik daripada teks Untuk menstimulasi visual spasial anak di TK Dharma Wanita II Tempurejo digunakan permainan VISIC (Visual Spatial of Rubic),yakni permainan yang menggunakan bangun terdiri dari 4 bagian permainan. Pada bagian pertama rubik terdapat warna-warna yang berbeda. Pada bagian kedua rubik terdapat permainan untuk mencari jalan. Pada bagian ketiga terdapat papan tulis kecil untuk anak menggambarkan imajinasinya. Pada bagian keempat rubik terdapat gambar geometri. Jenis penelitian yang digunakan yaitu deskriptif kualitatif, yang dilakukan di TK Dharma Wanita II Tempurejo, Jember pada bulan Oktober  2020. Sumber data 3 anak dengan kemampuan visual spasial yang berbeda, dan guru kelas. Metode pengumpulan data dilakukan melalui metode observasi, metode wawancara dan metode dokumentasi. Adapun teknik analisis data yang digunakan yaitu reduksi data, penyajian data, dan penarikan kesimpulan Berdasarkan hasil penelitian di TK Dharma Wanita II Tempurejo, Jember tentang analisis karakteristik kecerdasan visual spasial anak usia 4-5 tahun dalam permainan VISIC (Visual Spatial of Rubic) anak-anak dalam TK Dharma Wanita II Tempurejo, Jember memunculkan karateristik kecerdasan visual spasial.Hal tersebut terjadi secara bertahap.

Kata Kunci: Kecerdasan Visual Spasial, Permainan VISIC (Visual Spatial of Rubic)

 

Abstract

Visual Spatial is one of  intelligences that allows children to understand information by images better than text.To stimulate the visual spatial of children in TK Dharma Wanita II Tempurejo, VISIC (Visual Spatial of Rubic) is used, a game that uses shapes consisting of 4 game parts. In the first part of the Rubic there are different colors. In the second part of the Rubik there is a game to find a way. In the third part there is a small blackboard for children to describe their imagination. In the fourth section of the rubik there is a geometric drawing. The type of research used is descriptive qualitative, which was conducted at TK Dharma Wanita II Tempurejo, Jember in October 2020. Data sources were 3 children with different visual spatial abilities, and classroom teachers. Methods of data collection are carried out through observation methods, interview methods and documentation methods. The data analysis techniques used were data reduction, data presentation, and drawing conclusions. Based on the results of research at TK Dharma Wanita II Tempurejo, Jember, the analysis of the characteristics of the visual spatial intelligence of children aged 4-5 years in the VISIC (Visual Spatial of Rubic) game children in TK Dharma Wanita II Tempurejo, Jember bring out the characteristics of spatial visual intelligence. But This happens gradually.

Keywords: Visual Spatial Intelegence, VISIC(Visual Spatial of Rubic) game
Development of the professional culture of a music teacher among foreign students in the process of musical and instrumental training at a Russian pedagogical university
Authors: Maryatch Anastasiya Y. , Shipilkina Tatyana A.
Published: December 2021

We examine some of the problems of the process of developing the professional culture of a music teacher among foreign students from the Chinese People’s Republic in accordance with modern trends in Russian pedagogy of music education; the concept of “culture of piano performance-intonation” is revealed as a necessary component of the professional culture of a music teacher. The goal is to substantiate the need to study the features of the development of professional culture among Chinese students, future music teachers, in the process of musical and instrumental training at a Russian pedagogical university. In the course of the research, the concept of “professional culture of a music teacher” is clarified; the features of the development of the professional culture of a music teacher, and, in particular, the culture of piano performance-intonation among Chinese students, as its separate component, are investigated; the conditions for the upbringing of the culture of piano performance and intonation among foreign students in the process of musical and instrumental training in a Russian pedagogical university are determined. The research methodology is based on the systematization of scientific and pedagogical knowledge in the field of musicology, pedagogy and psychology of music education, as well as the results of experimental work carried out over the past three years on the basis of the “Special Piano” Department of the Tambov State Musical Pedagogical Institute named after S.V. Rachmaninov and the Music and Methods of Teaching Music Department of Penza State University.
The army and the collapse of the Habsburg Monarchy in 1918
Authors: Mironov Vladimir V.
Published: December 2021

The process of disorganization of the armed forces of Austria-Hungary in 1918 is considered through the prism of the national issue and the prospects for the further preservation of the Habsburg Monarchy. It is concluded that the military and diplomatic victories won in the early 1918 by Austria-Hungary were illusory and only put off the inevitable defeat of its army. Investigation of the first cases of mass withdrawal from obedience of military units in the spring and summer of 1918, showed that they were an interweaving of social, national-political and military reasons proper. At the same time, a serious discrepancy was revealed between Slovenian and Italian researchers in the interpretation of the reasons for the uprising in the 97th infantry regiment stationed in the Slovenian Radkersburg (Radgon). If for the former it was typical, following the Marxist tradition, to emphasize the social contradictions that led to the revolutionization of the army according to the “Russian model”, the latter praised the participants in the uprising from the Italian side as genuine national patriots. It is shown that the “shock force” of all the soldiers’ uprisings that broke out in the spring and summer of 1918 in the Austro-Hungarian army were servicemen who returned from Russian captivity in the spring of 1918, where some of them were imbued with revolutionary ideas. The conclusion is drawn about the extreme severity of military justice, which condemned many of the insurgents to death, which became the reason for deputy inquiries.
Linguodidactic potential of the model of content and language integrated learning of students in a foreign language and specialty in a medical university
Authors: Potapova Valentina Y.
Published: December 2021

The task of modern education is to train personnel of the highest category who would successfully cope with their professional tasks, were open to self-education, learning throughout their lives and were fluent in foreign languages. Knowledge of a foreign language has always been and remains a valuable knowledge. Content and language integrated learning is learning in which a foreign language is a tool for mastering a specialty, and not just the goal of learning a language as such. We examine the issue of the linguodidactic potential of the model of content and language integrated learning of students to a foreign language and specialty in a medical university, highlights a table of general requirements for students and teachers in the framework of content and language integrated learning, as well as the main direction in teaching, focuses on the advantages content and language integrated learning.
Experience tourism: development possibilities in the Bioceanic Corridor
Authors: Fittipaldi Gonçalves Débora , Boldrine Abrita Mateus , Cantero Dorsa Arlinda
Published: December 2021

The tourism sector is one of the most powerful generators of economic growth, employment, added value, and services export in the world. In this context, the objective of this article is to discuss tourism and experience tourism possibilities in the region that the Bioceanic Corridor will traverse from the Latin American Integration Route (RILA), involving Brazil, Paraguay, Argentine, and reaching Northern Chile in Antofagasta and Iquique. Regarding methodology, it uses the deductive method and is based on bibliographic and documentary research with access to the articles, indicators, and documents needed. In this regard, regional development issues are presented, followed by experience tourism as a possibility for development, and finally, some indicators and data about tourism are analyzed, seeking an interface with the Bioceanic Corridor. After analyses, it is pointed out that tourism has become one of the fundamental factors for territorial development, presenting new and other values and meanings to the territory, as well as a production resource, discovering another perspective when interpreting rural and natural spaces. Thus, it arises as a new alternative to globalization and, in this context, experience tourism gains prominence considering the significant increase of tourism in the world in 2010, and perspectives until 2030. It is inferred, therefore, that RILA is a great window of opportunity for socioeconomic development through tourism and more specifically experience tourism.
La La Ruta Bioceánica y las políticas públicas de los municipios fronterizos de Porto Murtinho/Brasil – Carmelo Peralta/Paraguay
Authors: Pinho de Almeida Luciane , Pereira da Silva Gabriela , De Souza Sales Gabriel , Elena Cunha de Laura Lívia
Published: December 2021

Con la llegada de la Ruta Bioceánica en el límite de los municipios de Porto Murtinho (Brasil) y Carmelo Peralta (Paraguay), la previsión es que se produzcan cambios sociales en la estructura de los municipios y su vida cotidiana. Este artículo pretende presentar reflexiones sobre los temas que permean las políticas públicas en la frontera, específicamente los municipios de Porto Murtinho y Carmelo Peralta. Este trabajo es el resultado del desarrollo de estudios para la elaboración del Plan Director para la ciudad de Porto Murtinho, los datos fueron recolectados entre septiembre de 2020 y junio de 2021 a través de entrevistas con los administradores públicos del municipio, cuestionarios aplicados con la población local, como así como también involucró investigaciones bibliográficas y documentales que ayuden a orientar nuevos caminos para las políticas locales. De los datos recogidos se observa que actualmente el municipio de Porto Murtinho cuenta con instalaciones públicas capaces de atender a la población, considerando su tamaño. Sin embargo, ante el aumento del flujo de personas y el posible aumento esperado de su población, las políticas públicas deben estar en consonancia con dicho desarrollo. Además, en la ciudad de Carmelo Peralta, la precariedad de los servicios públicos es evidente, especialmente en salud y asistencia social. Actualmente, muchos paraguayos ya utilizan servicios en el lado brasileño de la frontera porque no pueden acceder a su lugar de origen. Por ello, es de suma importancia que las políticas públicas consideren las particularidades de un municipio fronterizo que está por atravesar un momento de gran desarrollo, exigiendo diálogo y acuerdos bilaterales que tengan como objetivo garantizar los derechos sociales de las poblaciones locales.
Impactos de la implementación del Corredor Vial Bioceánico en la educación escolar en la frontera Brasil/Paraguay: conociendo el contexto
Authors: Basso Jaqueline , De Souza Ferretti Vanessa Arlésia
Published: December 2021

A pesar de sus méritos eminentemente económicos, regionales y geopolíticos, la implementación del Corredor Bioceánico: Ruta Porto Murtinho-Puertos del Norte de Chile también requiere de la inteligibilidad de sus diversos impactos sociales en las comunidades locales, incluidas las que afectan la educación pública. En este sentido, este trabajo tiene como objetivo comprender el contexto social, económico y educativo del municipio de Mato Grosso do Sul de Porto Murtinho, que limita con Carmelo Peralta en Paraguay y es el punto de partida de la Ruta en Brasil. Por ello, realizamos una investigación bibliográfica y estadística, mediante la recopilación y análisis de indicadores oficiales generados por el IBGE y el INEP. Los resultados identificaron que Porto Murtinho es un municipio pequeño, con una economía basada principalmente en la agricultura, las redes de educación pública atienden a poco más de cuatro mil estudiantes diariamente. Una demanda que está marcada por la diversidad cultural y lingüística dada la presencia de extranjeros y también de poblaciones indígenas. Por lo tanto, creemos que la implementación del Corredor Bioceánico se enfocará en un contexto que en sí mismo es diverso en términos culturales y lingüísticos y tenderá a incrementar la demanda de educación escolar ya que puede impulsar la permanencia de habitantes que actualmente no encuentran trabajo en el municipio y también la llegada de nuevos sujetos, dado el potencial crecimiento económico que representa la implementación del Corredor Bioceánico.
Strategi “TAK – JEMPOL (Tertib Administrasi Kependudukan dengan Jemput Bola)” bagi umat Hindu di desa Kayukebek Kecamatan Tutur Kabupaten Pasuruan
Authors: Abror M. Daimul
Published: December 2021

Penelitian ini bertujuan mendeskripsikan, menganalisis, dan menginterpretasikan strategi aparatur Desa dalam meningkatkan kesadaran tertib administrasi kependudukan di Desa Kayukebek dengan mengacu pada tipe-tipe strategi menurut Jack Koteen meliputi: Corporate strategy, Program strategy, Resource support strategy, dan Institutional strategy. Penelitian ini menggunakan metode penelitian kualitatif deskriptif. Informan dari penelitian ini adalah Kepala Desa, Sekretaris Desa sebagai pemegang peranan penting dalam keputusan pemerintahan Desa, Kaur bagian pelayanan administrasi kependudukan dan kepala adat umat Hindu sebagai informan kunci yang mengetahui permasalahan yang terjadi, masyarakat sebanyak 1-2 orang sebagai perwakilan dari masing-masing Dusun. Hasil penelitian menunjukkan, pertama kondisi administrasi kependudukan di Desa Kayukebek khususnya kalangan umat Hindu saat ini sudah mulai tertib dimana masyarakat dulunya tidak respon sekarang sudah mulai mengerti dan sadar akan pentingnya administrasi kependudukan. Kedua terdapat beberapa faktor yang menyebabkan warga kurang tertib administrasi kependudukan salah satunya yaitu masyarakat mengeluhkan akan biaya yang mahal, jarak tempuh ke balai desa jauh dan masyarakat kurang memiliki kesadaran dari awal sehingga ketika ada keperluan mendadak saja mereka baru mengurusnya, seperti kebutuhan untuk persyaratan pendaftaran masuk sekolah, pernikahan dan lain sebagainya. Ketiga, strategi aparatur desa dalam meningkatkan kesadaran tertib administrasi kependudukan di kalangan umat Hindu upaya yang dilakukan antara lain dengan mengadakan sosialisasi administrasi kependudukan, pemanfaatan sumber daya manusia, meningkatkan kemampuan aparatur desa untuk melakukan koordinasi dan kerjasama dengan instansi terkait administrasi kependudukan dan mendekatkan pelayanan secara langsung kepada masyarakat
PROSPECTS AND CHALLENGES OF FAIR TRANSFORMATION OF COAL REGIONS OF UKRAINE
Authors: Vovk O. , Rabosh І. , Kharchenko R. , Kukuyashnyy E.
Published: December 2021

The paper analyzes the changes taking place in recent years in the coal industry of Ukraine and the world and examines measures for innovation in energy. The main goals, challenges and prospects of fair transformation of coal regions are revealed by analyzing the current state of the coal industry of Ukraine and world trends. The instruments of the state policy on providing the fired workers of the coal regions with jobs in case of liquidation / transformation of mines are defined and the alternatives of the policy of promoting the employment of the fired workers for making effective decisions are established. Peculiarities and factors of creation of technological or eco-technological parks on the basis of coal enterprises are studied. It is concluded that one of the effective solutions for the fair transformation of coal regions can be the transformation / transformation of the mine as a state enterprise into a park system by involving energy companies. The implementation of investment projects using the infrastructure of the mine for other activities is promising. Significant work should be done on job creation programs and training / retraining / retraining of workers, design of industrial parks and implementation of innovative projects.
Design features of piezoelectric motors
Authors: Miroshnichenko A.P. , SHorohov A.E.
Published: December 2021

The features of the piezoelectric motor designs with improved efficiency and starting torque are considered, suggested a version of application design, which allows doubling the speed while maintaining starting torque
FLAMMABILITY OF HYDROCARBON FRACTIONS OBTAINED BY DESTRUCTION OF POLYMER RAW MATERIALS
Authors: Shevchenko Kyryl Volodymyrovych , Grigorov Andriy Borysovych
Published: December 2021

The article discusses the possibility of using hydrocarbon fractions – products of thermal destruction of polymer raw materials (polyethylene and polypropylene) at atmospheric pressure as components of commercial diesel fuels. This approach allows, on the one hand, to improve the properties of commercial diesel fuel, on the other, to increase the competitiveness of domestically produced products. In addition, the problem associated with the accumulation of polymer waste and their negative impact on the environment is also partially solved.

The nature of the dependences between such indicators of the quality of fractions 160–350 °C, 200–350 °C, 240–350 °C as the autoignition temperature, the initial boiling point of the fraction and the cetane number as an indicator characterizing the flammability, has been established. The dependence of the autoignition temperature on the boiling point of the fractions has a polynomial character and indicates a decrease in the autoignition temperature with an increase in the boiling point of the fractions. The dependence of the cetane number on the initial boiling point of the fractions is linear and indicates an increase in the cetane number with an increase in the initial boiling point of the fractions. The dependence of the cetane number on the autoignition temperature of the fractions has a polynomial character and indicates a decrease in the cetane number with an increase in the autoignition temperature of the fractions.

It was found that the autoignition temperature of the investigated fractions, regardless of the type of polymer raw material, fluctuates in a rather narrow range, from 229 to 348 ° C, and the cetane number – from 41 to 55 units. Based on the literature data, we note that exactly this range is close to the range that commercial diesel fuels have, and the fractions studied by us can be used in the production of diesel fuel.
COMPARATIVE ASSESSMENT OF GASEOUS FUEL EMISSION
Authors: Levytska Olena Hryhoriivna , Voytenko Yulia Vladimirovna , Orishechok Anastasiia Oleksiivna
Published: December 2021

The work presents estimated comparative assessment of emissions release in combustion products during work of high–power steam boilers with the use of traditional fuel – natural gas and alternative fuels – blast–furnace and coke–oven gases generated in the process of technological cycle at iron and steel and coke–chemical enterprises. Calculation algorithm is shown and formulas for assessment of carbon content in exhaust gases are defined, conclusions on ecological efficiency of gaseous fuels are given.

The purpose of the work was to evaluate the emissions of harmful substances generated during the combustion of natural, blast furnace and coke oven gases, justification of the calculation of carbon content of a given chemical composition and determine the optimal environmental impact of analogues of natural gas.

The comparative estimation of pollutant emissions into atmospheric air during combustion of natural, coke oven and blast furnace gases revealed:

– high sulfur dioxide emissions from combustion of blast furnace and coke oven gases due to the presence of sulfur compounds in the composition of these gases;

– relatively high emissions of nitrogen compounds for natural and coke oven gases and relatively low emissions for blast furnace gas;

– сarbon emissions are high for all types of fuels which have been considered, most carbon dioxide gets into  the air when burning natural gas, least – when burning blast furnace gas;

– significantly higher methane emissions are observed during the combustion of natural and coke oven gases, respectively, smaller – for blast–furnace gas combustion;

– coke oven and natural gases are characterized by low mercury emissions.

Comparative assessment of the calculated values of hazardous substances emissions in the combustion products in the process of combustion of natural, coke–oven and blast–furnace gases shows that even at lower working heat of combustion values the coke–oven and blast–furnace gases can compete with natural gas.

For the first time, a comparative characterization of the emissions of harmful substances in the combustion of natural, coke oven and blast furnace gases is presented, and it is shown that the gases used in coke and metallurgical industries, which are used as analogues of natural, are logical to use, but require the installation of treatment systems. The paper defines a formula for calculating the carbon content in natural gas from the Urengoy–Uzhhorod gas pipeline. The provided calculations and the introduction of simplified formulas serve as an example for the calculation of emission factors and emissions in assessing the level of safety of existing equipment and can be used in the development of permit documents of enterprises that carry out emissions of harmful substances to the environment.
Анализ динамики эпидемического процесса COVID-19 в мире за неделю с 11.12.2021 г. по 17.12.2021 г.
Authors: Зимирова Анастасия , Поспелов Михаил , Иванова Александра , Дмитриева Людмила , Чумачкова Елена , Карнаухов Игорь , Щербакова Светлана , Кутырев Владимир
Published: December 2021

В обзоре представлен анализ эпидемиологической ситуации в странах мира по COVID-19, за неделю с 11.12.2021 г. по 17.12.2021 г.
Распространение вариантов вируса SARS-COV-2, вызывающих озабоченность (VOC) и интерес (VOI) на основе количества их геномов, депонированных в базу данных GISAID за неделю с 11.12. по 17.12.2021 г.
Authors: Дмитриева Людмила , Чумачкова Елена , Краснов Ярослав , Осина Наталья , Сафронов Валентин , Иванова Александра , Карнаухов Игорь , Караваева Татьяна , Щербакова Светлана , Кутырев Владимир
Published: December 2021

В обзоре представлен анализ геновариантов вируса SARS-CoV-2, вызывающих озабоченность (VOC) и интерес (VOI) на основе их геномов в базе GISAID за неделю с 11.12.2021 г. по 17.12.2021 г.
SLUPT: Synthesis of libraries and multi-site mutagenesis using a PCR-derived, dU-containing template Protocol
Authors: Meinke Gretchen , Bohm Andrew
Published: December 2021

SLUPT stands for Synthesis of Libraries and Multi-Site Mutagenesis using a PCR derived, U-containing Template. SLUPT enables the user to create a DNA library, and/or multiple mutations of a given DNA target, independently or simultaneously. In particular, when SLUPT is used in conjunction with known structural and sequence homology data, one can create highly directed libraries/mutations spread across the gene of interest.
What lies underneath: Precise classification of brain states using time-dependent topological structure of dynamics
Authors: Soler-Toscano Fernando , Galadí Javier , Escrichs Anira , Sanz-Perl Yonatan , López-González Ane , Sitt Jacobo , Annen Jitka , Gosseries Olivia , Thibaut Aurore , Panda Rajanikant , Esteban Francisco J. , Laureys Steven , Kringelbach Morten , Langa José A. , Deco Gustavo
Published: December 2021

The self-organising global dynamics underlying brain states emerge from complex recursive nonlinear interactions between interconnected brain regions. Until now, all efforts of capturing the causal mechanistic generating principles have proven elusive, since they have been unable to describe the non-stationarity of brain dynamics, i.e. time-dependent changes. Here, we present a novel framework able to characterise brain states with high specificity, precisely by modelling the time-dependent dynamics. Through describing the topological structure of the brain at each moment in time (its ‘information structure’), we are able to classify different brain states by using the statistics across time of these exact ‘information structures’ hitherto hidden in the neuroimaging dynamics. Proving the strong potential of this framework, we were able to classify the neuroimaging data from two classes of comatose patients (minimally conscious state and unresponsive wakefulness syndrome) compared with healthy controls with very high precision.
The m6A reader IGF2BP3 Facilitates Gastric Cancer Progression Through Activating EMT via Upregulating MYC mRNA Stability
Authors: Ren Yiyi , Du Dandan , Liu Tong , Wang Chuntao , Yan Qinyu , Li Chengyun , Wang Xinghua , Yang Sheng , Kong Lu , Liang Geyu
Published: December 2021

Background: N6-methyladenosine (m6A) RNA methylation plays an important biological role in cancer progression. Even so, the role of m6A modification in gastric cancer (GC) still needs further research. Methods: Firstly, based on the bioinformatics databases and human GC tissues analysis. Secondly, the IGF2BP3 expression in GC cells was measured by the quantificational real-time polymerase chain reaction and Western Blot. Then, the IGF2BP3 knockdown stable cells model was successfully constructed with the specific lentivirus-mediated short-hairpin RNA to explore the functions and mechanism of IGF2BP3 in GC. Next, the functions of IGF2BP3 on the cell phenotypes, including proliferation, invasion, migration, and Epithelial-mesenchymal transition process were clarified by the Cell Counting Kit-8, transwell, and WB experiments. Subsequently, RNA Immunoprecipitation analysis and mRNA stability experiments were used to verify the relationship between IGF2BP3 and MYC. Finally, in the rescue experiment, MYC was overexpressed and transfected into IGF2BP3 knockdown cells to further detect the influences on the cell phenotypes and the EMT process.Results: IGF2BP3 was up-regulated in GC. Meanwhile, IGF2BP3 had diagnostic and prognosis values for GC. Functionally, knockdown IGF2BP3 repressed gastric cancer cells proliferation, migration invasion and EMT process. Mechanically, IGF2BP3 activated the EMT process by improving the expression of MYC via combining with MYC mRNA and promoting its stability. Conclusions: Taken together, IGF2BP3 could activate the EMT process via increasing the MYC mRNA stability and expression to promote GC development, which provided insight into promising early diagnose and treatment for gastric cancer.
Treatment of Severe Bone Destruction in L5-S1 Spinal Tuberculosis With Anterior Combined Posterior Approach
Authors: Xue Jing , Li Tao , Song Yueming , Liu Hao , Liu Limin , Gong Quan
Published: December 2021

Background: There are many studies on the surgical treatment of lumbosacral tuberculosis, but both the anterior and posterior approaches present some shortcomings. This study aimed to evaluate the therapeutic efficacy of anterior debridement and bone graft, posterior fixation and fusion with navigation for L5-S1 tuberculosis with severe bone destruction. Methods: This was a retrospective study of 24 patients with severe tuberculosis in L5-S1 who underwent anterior interbody arthrodesis and posterior pedicle screw internal fixation by open approach under computer navigation between February 2011 and Novenmber 2016. The erythrocyte sedimentation rate(ESR), C-reactive protein level(CRP),visual analogue scale(VAS), and lumbosacral angle were compared between before surgery, after surgery, and at the final follow-up. The fusion status of bone graft was evaluated with computed tomography(CT).Results: The mean operation time was 244.58 minutes. The mean intraoperative blood loss was 413.75ml. The accuracy of screw placement was 96.43%. The mean follow-up period was 26.17 months. The average ESR, CRP, VAS, and lumbosacral angles were 65.96 mm/h, 52.93 mg/L, 4.96 points ,and 107.94°, respectively,at preoperative, 34.17 mm/h, 16.47 mg/L, 1.58 points, and 116.12°, respectively, after surgery, and 14.08 mm/h, 6.20 mg/L, 0.58 points, and 115.97°, respectively, at the final follow-up period. The differences of ESR, CRP, VAS are statistically significant (p < 0.05). The difference of lumbosacral angles before and after surgery is statistically significant (p < 0.05)，but there is no statistically significant difference between after surgery and the final follow-up period (p＞0.05). Nine patients with ASIA Grade D before surgery returned to Grade E by the final follow-up period. All patients achieved bone fusion.There was no recurrence of the disease. Conclusions: Anterior debridement and bone graft fusion combined with navigated posterior pedicle screw fixation is a safe and effective treatment option for patients with severe bone destruction in L5-S1 spinal tuberculosis.
Human Papillomavirus Prevalence and Genotype Distribution Landscapes in Shannan City, Tibet Tibetan Autonomous Region, China
Authors: Feng Dilu , Wei Sitian , Chen Jun , Yu Zhicheng , Wang Hongbo , Zhu Xiaowu
Published: December 2021

Background:
Data regarding human papillomavirus (HPV) prevalence and genotype distribution are limited in Shannan City, Tibet Tibetan Autonomous Region, China. The purpose of this study is to provide reliable data for guiding women in Shannan City in cervical cancer screening and HPV vaccine innoculation.
Methods:
HPV testing was performed on women aged 16 to 109 years (mean age 44.03 ± 9.25 years) from Shannan City in 2019 and 2020, which was implemented technically by gynecological examination, vaginal discharge smear microscopy, cytology, and HPV detection. The overall prevalence, age-specific prevalence, and genotype distribution were analyzed.
Results:
A total of 48,126 women received HPV testing, of which 3,929 were detected human papillomavirus. The HPV-positive rate was 8.16% (3,929/48,126), and the highest prevalence was in the ≤ 25-year-old age group (12.68%). After the age of 25, the prevalence rate decreased rapidly, and then slowly increased from 7.49% in the 46-55 age group to 9.82% in the ≥ 66 age group, showing a “U-shaped” pattern. The positive prevalence of HPV 16 or 18-only was 1.43%, that of other HPV genotypes except HPV 16 or 18 was 6.39%, and mixed HPV infections including HPV 16 or 18 was 0.34%.
Conclusions:
The HPV infection rate in Shannan city is rather low, and the age-specific prevalence of HPV infection presents a “U” curve, suggesting the importance of screening among younger women and the necessity of detection among older women.
Towards Understanding the Risks of Gradient Inversion in Federated Learning
Authors: Hatamizadeh Ali , Yin Hongxu , Molchanov Pavlo , Myronenko Andriy , Li Wenqi , Dogra Prerna , Feng Andrew , Flores Mona , Kautz Jan , Xu Daguang , Roth Holger
Published: December 2021

Federated learning (FL) allows the collaborative training of AI models without needing to share raw data. This capability makes it especially interesting for healthcare applications where patient and data privacy is of utmost concern. However, recent works on the inversion of deep neural networks from model gradients raised concerns about the security of FL in preventing the leakage of training data. In this work, we show that these attacks presented in the literature are impractical in real FL use-cases and provide a new baseline attack that works for more realistic scenarios where the clients’ training involves updating the Batch Normalization (BN) statistics. Furthermore, we present new ways to measure and visualize potential data leakage in FL. Our work is a step towards establishing reproducible methods of measuring data leakage in FL and could help determine the optimal tradeoffs between privacy-preserving techniques, such as differential privacy, and model accuracy based on quantifiable metrics.
Spatial Distribution Analysis of Community Radio Stations For Promoting Climate Change Adaptation Measures in Agriculture Under COVID-19 Scenario, Southern Province, Zambia
Authors: Somanje Albert , Mwansa Lauraine , Chisanga Kafula
Published: December 2021

Community Radio Stations (CRS) play an important role in information dissemination at local and context specific levels. This study analyzes the spatial distribution of the CRS and their role in promoting sustainable in agriculture in times of Coronavirus Disease (COVID-19). The study's methodological approach included geospatial mapping of CRS in Arc GIS 10.3, surveys and interviews with key informants (n=39). In addition, the data was analyzed using SPSS 28.0 for frequency and descriptive analysis and excel for graphical outputs. The study finds 19 CRS in 13 districts and their radii completely cover the Southern Province of Zambia. Out of the time allocated to agricultural programs, an average of 47% is on climate change adaptation measures in local languages. However, the CRS have limited access to experts to provide information and programs sponsorship. This study has established that CRS have potential in disseminating climate change adaptation measures. Sixty-nine percent (69%) of the CRS noticed an increase in demand for agricultural programs during the COVID-19 era, with the rapid growth of CRS. The study recommends stakeholders collaboration to provide appropriate information to enhance the climate agricultural programmes on CRS and address challenges of limited access to experts and associated costs.
Casimir Forces Out of Thermal Equilibrium Near A Superconducting Transition
Authors: Castillo-López Shunashi Guadalupe , Esquivel-Sir Raúl , Pirruccio Giuseppe , Villarreal Carlos
Published: December 2021

We present a comprehensive analysis of the out-of-equilibrium Casimir pressure between two high-T c superconducting plates, each kept at a different temperature. Two interaction regimes can be distinguished. While the zero-point energy dominates in the near field, thermal effects become important at large interplate separations causing a drop in the force’s magnitude compared with the usual thermal-equilibrium case. Our detailed calculations highlight the competing role played by propagating and evanescent modes. Moreover, as one of the plates undergoes the superconducting transition, we predict a sudden discontinuity in the force for any plate distance, which has not been previously observed in other systems. The sensitivity of the dielectric function of the high-T c superconductors makes them ideal systems for a possible direct measurement of the out-of-equilibrium Casimir pressure.
Investigation On Mechanism of Ultrasonic Welding AZ31B / 5052 Joint With Laser Texturing On Mental Surface
Authors: Wang Cailing , Xing Yanfeng , Hu Jingyao , Luo Junding , Zeng Sheng
Published: December 2021

The ultrasonic welding was carried out to improve the quality of dissimilar Al/Mg alloys joint. The effects of laser texturing on the microstructure and mechanism of AZ31B/5052 joint connected by ultrasonic welding were also investigated. A series of laser texturing experiments on Al alloy (5052) and Mg alloy (AZ31B) were performed to determine the process parameters and their ef-fect on ultrasonic weld quality, especially on weld strength. Little effect was attained by opti-mizing welding parameters in improving mechanical properties. Both welding parameters and different texture pattern were investigated to obtain good weld quality. The connection mecha-nisms of joints were discussed based on the analysis of weld interface morphology, microstruc-ture evolution. Mechanical analysis of particle and movement of material atoms were analyzed in the study to explain the connect mechanism. The results show that the better lock-interface and lager lap shear strength were attained by laser texture addition and optimal welding parameters. Compared with the untextured joint, swirling bonding interface was obtained after the laser tex-ture. The laser texture with grid pattern was found to raise the strength up to 26% higher maxi-mum tensile-shear load than the joints obtained with the untextured surface.
Spatiotemporal Dynamics of Bacterial Taxonomic and Functional Profiles in Estuarine Intertidal Soils of China Coastal Zone
Authors: Zhang Zongxiao , Han Ping , Zheng Yanling , Jiao Shuo , Dong Hongpo , Liang Xia , Gao Dengzhou , Niu Yuhui , Yin Guoyu , Liu Min , Hou Lijun
Published: December 2021

Estuarine intertidal wetlands pertain to habitats with high productivity on Earth. Bacteria in estuarine intertidal soils regulate carbon (C), nitrogen (N) and sulfur (S) cycles. To gain insights into the ecological and metabolic modes possessed by bacteria in estuarine intertidal wetlands, we explored the spatial and seasonal variations of bacterial taxonomic composition, assembly processes, and ecological system functions in surface soils from China’s estuarine intertidal flats through shotgun metagenomic and 16S rRNA gene sequencing. Obvious spatiotemporal dynamic patterns in the bacterial community structure were identified, with more pronounced seasonal rather than spatial variations. Dispersion limitation was observed to act as a critical factor affecting community assembly, explaining approximately half of the total variation in bacterial community. Functional bacterial community structure exhibited a more significant latitudinal change than seasonal variability, highlighting that functional stability of the bacterial communities differed with their taxonomic variability. Identification of biogeochemically related links between C, N and S cycles in the soils showed the adaptive routed metabolism of the bacterial communities and the strong interactions between coupled metabolic pathways. Our study broadens the insights into the taxonomic and functional profiles of bacteria in China’s estuarine intertidal soils from various latitudes and helps us understand the effects exerted by environmental factors or climate-related variations on the ecological health and microbial diversity of estuarine intertidal flats.