bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of the photocatalytic efficacy and environmental impact of CdS, ZnFe2O4, and NiFe2O4 under visible light irradiation
Authors: Wang Xiaoyu , Masten Susan J. , Esfahanian Elaheh
Published: February 2021

Three photocatalysts (CdS, ZnFe2O4, and NiFe2O4) were synthesized and their ability to photodegrade methylene blue (MB) was evaluated. MB was degraded by both spinel photocatalysts under visible light at room temperature, although their efficacy was less than that for CdS. The photocatalytic efficacies of NiFe2O4 were observed to be much greater than that for ZnFe2O4. All the synthesized nanoparticles absorbed visible light, while CdS had a larger absorption range within the visible light spectra and the most porous surface. Photo-deactivation was observed during the study, which could be due to the chemical adsorption of the degraded products on the catalyst surface. The factors that affected MB removal efficacy include the absorption range of photocatalysts, initial MB concentrations, amount of photocatalysts added, and photoreactor conditions. Life cycle analysis was used to compare the preparation methods of the photocatalysts in terms of energy consumption and environmental impact. The results showed that the hydrothermal method for NiFe2O4 preparation was less energy-intensive than the sol-gel method for CdS and ZnFe2O4 as the hydrothermal method is effective over a wider range of temperatures in aqueous media. Also, as ZnFe2O4, and NiFe2O4 have lower environmental impacts than CdS both show promise as photocatalysts.
Support vector machines for oil classification link with polyaromatic hydrocarbon contamination in the environment
Authors: Ismail Azimah , Juahir Hafizan , Mohamed Saiful Bahri , Toriman Mohd Ekhwan , Kassim Azlina Md. , Zain Sharifuddin Md. , Monajemi Hadieh , Ahmad Wan Kamaruzaman Wan , Zali Munirah Abdul , Retnam Ananthy , Taib Mohd. Zaki Mohd. , Mokhtar Mazlin , Abdullah Siti Nor Fazillah
Published: February 2021

The main focus of this study is exploring the spatial distribution of polyaromatics hydrocarbon links between oil spills in the environment via Support Vector Machines based on Kernel-Radial Basis Function (RBF) approach for high precision classification of oil spill type from its sample fingerprinting in Peninsular Malaysia. The results show the highest concentrations of Σ Alkylated PAHs and Σ EPA PAHs in ΣTAH concentration in diesel from the oil samples PP3_liquid and GP6_Jetty achieving 100% classification output, corresponding to coherent decision boundary and projective subspace estimation. The high dimensional nature of this approach has led to the existence of a perfect separability of the oil type classification from four clustered oil type components; i.e diesel, bunker C, Mixture Oil (MO), lube oil and Waste Oil (WO) with the slack variables of ξ ≠ 0. Of the four clusters, only the SVs of two are correctly predicted, namely diesel and MO. The kernel-RBF approach provides efficient and reliable oil sample classification, enabling the oil classification to be optimally performed within a relatively short period of execution and a faster dataset classification where the slack variables ξ are non-zero.
Acessibilidade
Authors: Brandão Alves do Pinho Bruna , Christinna Maria Portugal Alinne , Braga Barbosa Bárbara
Published: February 2021

Com o alicerce da Constituição Federal de 1988 e através de tantos outros instrumentos legais, a acessibilidade se tornou um direito, não somente social, mas também uma exigência legal com regulamentação bem dirigida. A acessibilidade arquitetônica e urbanística visa proporcionar capacidade de alcance e acesso aos edifícios e espaços urbanos, através da eliminação das barreiras presentes nas cidades. O presente artigo é uma revisão bibliográfica baseada em trabalhos acadêmicos, leis, normas técnicas e manuais de acessibilidade de órgãos e entidades da Administração Pública e Conselho de Classe, que retrata o atual contexto sobre a temática no Brasil, expõe algumas dificuldades encontradas na prática e destaca a relevância de se projetar espaços acessíveis, sejam eles públicos ou privados. Deste modo, pode-se observar que são muitos os esforços que ainda devem ser despendidos para alcançar a autonomia e segurança nos acessos aos espaços, como capacitação e compromisso profissional, intensificação das ações fiscalizadoras, disseminação de ações efetivas e fomento do projeto inclusivo.
Decreased lncRNA SNHG16 Accelerates Oxidative Stress Induced Pathological Angiogenesis in Human Retinal Microvascular Endothelial Cells by Regulating miR-195/mfn2 Axis
Authors: Zhang Rui , Ma Xiaoying , Jiang Lei , Xia Wenzhen , Li Haipeng , Zhao Na , Cui Ximing , Zhang Nan , Zhou Huimin , Xu Shunjiang
Published: February 2021

Background:

This study was performed to identify the alterations of Long non-coding RNAs (lncRNAs) induced
by oxidative stress and investigate the functional roles of SNHG16 in the pathological angiogenesis by human retinal
microvascular endothelial cells (HMRECs).

Methods:

The expression profiles of lncRNAs and mRNAs induced by oxidative stress were identified by
RNA-Seq, and the dysregulation of 16 lncRNAs including SNHG16 was verified in H2O2-treated human umbilical
vein endothelial cells (HUVECs). Luciferase reporter assay and RIP analysis were used to investigate the
binding relationship of SNHG16 to miR-195.

Results:

We confirmed that over-expression of SNGH16 attenuated H2O2-induced angiogenesis by HMRECs.
In addition, SNHG16 was significantly decreased, whereas miR-195, a predictive target of SNHG16, was upregulated
in H2O2, HG, and AGE-treated HMRECs. The binding relationship of SNHG16 to miR-195 was subsequently
verified by luciferase reporter assay and RIP analysis. SNHG16 cotransfection abolished miR-195-mediated
repression on mitofusin 2 (mfn2) protein level and counteracted the inductive effect of miR-195 on angiogenesis
by HMRECs.

Conclusion:

These results indicated that decreased SNHG16 accelerates oxidative stress-induced pathological
angiogenesis in HMRECs by regulating the miR-195/mfn2 axis, providing a potential target for diabetic retinopathy
(DR) therapy.
Deciphering the Role of Nanoparticle-based Treatment for Parkinson’s Disease
Authors: Moni Md. Marufur Rahman , Begum Mst. Marium , Uddin Md. Sahab , Ashraf Ghulam Md
Published: February 2021

Parkinson’s disease (PD) is a progressive neurodegenerative disorder that exerts a huge burden on
our society. The occurrence of this neurodegenerative disease has been increasing day-by-day. PD can be a serious
concern if the patients are left untreated. However, conventional treatment has many side-effects and less
bioavailability in the brain. Therefore, the necessary measurement is required to solve the limitations of PD
treatment. Nanotechnology has made a major contribution to comprehend PD pathogenesis. Nanotechnology
can provide efficient therapies that have reduced side-effects and increased bioavailability in the brain. This review
emphasizes the emerging promise of nanoparticle-based treatment, drug delivery, and other therapeutic approaches
for PD. Besides, the advantages of different approaches on nanotechnology platforms are far better
over conventional therapy in the treatment of PD.
The Role of Biosynthesized Silver Nanoparticles in Antimicrobial Mechanisms
Authors: Backx Bianca P. , dos Santos Mayara S. , dos Santos Otávio A.L. , Filho Sérgio A.
Published: February 2021

Nanotechnology is an area of science in which new materials are developed. The correlation
between nanotechnology and microbiology is essential for the development of new drugs and vaccines.
The main advantage of combining these areas is to associate the latest technology in order to obtain
new ways for solving problems related to microorganisms. This review seeks to investigate nanoparticle
formation's antimicrobial properties, primarily when connected to the green synthesis of silver nanoparticles.
The development of new sustainable methods for nanoparticle production has been instrumental
in designing alternative, non-toxic, energy-friendly, and environmentally friendly routes. In
this sense, it is necessary to study silver nanoparticles' green synthesis concerning their antimicrobial
properties. Antimicrobial silver nanoparticles' mechanisms demonstrate efficiency to gram-positive
bacteria, gram-negative bacteria, fungi, viruses, and parasites. However, attention is needed with the
emergence of resistance to these antimicrobials. This article seeks to relate the parameters of green silver-
based nanosystems with the efficiency of antimicrobial activity.
Dual Functionality of Choline Hydroxide for the Dakin Reaction
Authors: Joo Seong-Ryu , Kim Seung-Hoi
Published: February 2021

:

A facile synthetic approach to Dakin oxidation utilizing green conditions was demonstrated. A combination of
hydrogen peroxide and aqueous choline hydroxide in cooperation with various hydroxyl aryl aldehydes and ketones was
used to provide the corresponding dihydric aromatic compounds. The whole procedure was conducted at ambient temperature in an aerobic environment. The scope of ChOH/H2O2 platform was also investigated, showing that the reactivity of the
present platform was highly dependent on the position of the hydroxy group of the aromatic ring.
Chiral Polymorphic Hydrazine-based Asymmetric Liquid Crystal Trimers with Resorcinol as Linking Group
Authors: Goh Yit-Peng , Yam Wan-Sinn , Yip Foo-Win , Hegde Gurumurthy
Published: February 2021

Introduction:

This is the first report on chiral polymorphic hydrazine-based asymmetric liquid crystal
trimers, 1-[4'-(4''-(5-Cholesteryloxy)carbonyl)butyloxy]-3-[N-benzylideneoxy-N'-(4'''-decyloxybenzylidene) hydrazine]
butyloxybenzenes, and 1-[4'-(4''-(10-cholesteryloxy)carbonyl)nonyloxy]-3-[N-benzylideneoxy-N'-(4'''-
decyloxybenzylidene)hydrazine]butyloxybenzenes., in which the hydrazine and cholesterol arms were connected
via two flexible methylene spacers (n = 3-12 units and m = 4 or 9, respectively) to the central resorcinol core.

Materials and Methods:

FT-IR, 1D and 2D NMR spectroscopy, and CHN microanalysis were used to elucidate
the structures of the trimers. Differential scanning calorimetry, polarizing optical microscopy and X-ray diffraction
were used to study the transitional and phase properties of the trimers, which were length and spacer parity
dependent. Trimers with short spacer length in the cholesteryl arm, m = 4 showed an interesting phase sequence
of BP/N*-TGBA*-SmA*.

Results and Discussion:

The TGBA* phase was sensitive to spacer length as it was only observed in trimers with
short ester linkage. For the long analogues, m = 9, characteristic visible reflection and a much simpler phase sequence
with only N* and SmA* phases were observed.

Conclusion:

The X-ray diffraction measurements revealed that layer periodicities of the SmA* phase were approximately
half the estimated all-trans molecular length (d/L ≈ 0.44-0.52), thus suggesting that the molecules
are either strongly intercalated or bent.
Cluster Analysis of Coronavirus Sequences using Computational Sequence
Descriptors: With Applications to SARS, MERS and SARS-CoV-2
(CoVID-19)
Authors: Vračko Marjan , Basak Subhash C. , Dey Tathagata , Nandy Ashesh
Published: February 2021

Introduction:

Coronaviruses comprise a group of enveloped, positive-sense single-stranded RNA viruses that infect humans
as well as a wide range of animals. The study was performed on a set of 573 sequences belonging to SARS,
MERS and SARS-CoV-2 (CoVID-19) viruses. The sequences were represented with alignment-free sequence
descriptors and analyzed with different chemometric methods: Euclidean/Mahalanobis distances, principal component
analysis and self-organizing maps (Kohonen networks). We report the cluster structures of the data. The
sequences are well-clustered regarding the type of virus; however, some of them show the tendency to belong
to more than one virus type.

Background:

This is a study of 573 genome sequences belonging to SARS, MERS and
SARS-CoV-2 (CoVID-19) coronaviruses.

Objective:

The aim was to compare the virus sequences, which originate from different places
around the world.

Methods:

The study used alignment free sequence descriptors for the representation of sequences
and chemometric methods for analyzing clusters.

Results:

Majority of genome sequences are clustered with respect to the virus type, but some of
them are outliers.

Conclusion:

We indicate 71 sequences, which tend to belong to more than one cluster.
Design, Synthesis and Biological Evaluation of 1-methyl-1H-pyrazole-5-Carboxamide Derivatives as Novel Anti-Prostate Cancer Agents
Authors: Chen Xin , Xu Changqing , Li Yuxia , Duan Xiaoming , Zhao Guisen
Published: February 2021

Background:

The Androgen Receptor (AR) signaling functionis a critical driving force for the progression
of Prostate Cancer (PCa) to bring about anti-prostate cancer agents, and AR has been proved to be an
effective therapeutic target even for Castration-Resistant Prostate Cancer (CRPC). Objective: In order to discover
novel anti-prostate cancer agents, we performed structural modifications based on the lead compounds T3
and 10e.

Methods:

A set of 1-methyl- 1H-pyrazole-5-carboxamide derivatives were synthesized and evaluated for their
inhibitory activities against both expressions of Prostate-Specific Antigen (PSA) and growth of PCa cell lines.

Results:

Compound H24 was found to be able to completely block PSA expression at 10μM, and showed
prominent antiproliferative activity in both the LNCaP cell line (GI50 = 7.73μM) and PC-3 cell line (GI50 =
7.07μM).

Conclusions:

These preliminary data supported a further evaluation of compound H24 as a potential agent to
treat prostate cancer.
Industrial Wastewater: Health Concern and Treatment Strategies
Authors: Singh Shubhi , Sharma Akanksha , Malviya Rishabha
Published: February 2021

Water is a basic need for the functioning of all life forms that exist on earth. However, current water resources are being polluted by anthropogenic sources, which include social unit, as well as agricultural and industrial waste. People all over the world have concerns about the impact of effluent pollution on the atmosphere, which is increasing day by day. It is hard to purify wastewater before it flows into water reservoirs. Hence, the treatment of wastewater remains an essential need before it is allowed to enter natural water streams. Wastewater treatment is relatively a modern practice. This review will particularly discuss the ways of heavy metal ion removal from wastewater. The ultimate purpose of wastewater management is to improve the health of human and environmental aspects.
Nothobranchius Fish: An Untapped Resource for Studying Aging-Related Neurodegeneration
Authors: Genade Tyrone , Wilcox Dale A.
Published: February 2021

New models in which aging-related neurodegeneration more closely resembling the
combination of pathologies that develop in aging humans, are needed. The fish Nothobranchius,
which naturally develops such pathologies over the course of its short lifespan, is one such model.
This review compares the lifespans and pathologies of different Nothobranchius strains to those of
current vertebrate models of aging. Furthermore, existing data pertaining to neurodegeneration in
these fish is discussed in the context of their reported neuropathologies, along with open questions
related to mammalian chronopathologies. Specifically, the evidence for a Parkinson’s disease-like
pathology is discussed. Neurogenesis and age-related changes therein are discussed in the context
of siRNA and neurodegeneration. We also discuss changes in the expression of neuropeptide Y in
relation to the brain-gut axis and how these change with age. Age-related behavioral changes are
discussed, along with the assays used in their evaluation. Genetic discoveries are outlined and discussed
with a view on DJ-1/NRF2 signaling in N. furzeri, and insights gained from comparative
genomics and siRNA studies. Finally, research focus areas are highlighted, and a case is made for
the utility of these fish in the study of aging-related neurodegeneration, and to screen for environmental
risk factors of aging-related neuropathology.
Challenges of Covid-19 on Adolescent Psychiatric Service Provision in an Independent Inpatient and Outpatient Setting
Authors: Bond Laura , Murtagh Aileen , Morgan Sophia
Published: February 2021

Background:

COVID-19 is one of the most challenging and devastating
public health emergencies we have experienced in our lifetimes. There is a growing
concern that the pandemic and its imposed public health restrictions may be
harming a generation of young people. This article concerns child and adolescent
psychiatry as there is already a mismatch between resources and demand.

Method:

This paper will outline the day to day working challenges encountered by
the SPMHS adolescent service, staff, and patients in the initial months of the
COVID-19 crisis and some of the strategies implemented to deal with these.

Discussion:

In St. Patrick’s University Hospital in Ireland, significant challenges in
the adolescent service were encountered in the initial months of the COVID-19
crisis. These included the cessation of face-to-face patient interactions, therapeutic
leave and visiting restrictions, school closure, social restrictions, difficulties in
organizing medical appointments and investigations, family stress and increased
workload for staff. Strategies including telepsychiatry have enabled the delivery of
an efficient and accessible adolescent service during this crisis.

Conclusion:

Future research is required to analyse how best we can support
children and adolescents during COVID-19, particularly those with existing mental
illness is crucial.
Neurovirulence of SARS CoV2: From Clinical Data to Preclinical Neuropsychological
Exploration
Authors: Kadil Youness , Filali Houda
Published: February 2021

Introduction:

COVID-19 pandemic represents a major health issue, caused by SARS CoV2, a Human
coronavirus. Since the outbreak of this pandemic, the literature on SARS CoV-2 has grown differentially, with increased
awareness of extra-respiratory symptoms, including neurological symptoms.

Methods:

Review based on studies published in the period extending through December 2019 to June 2020.

Results and Discussion:

This review raises the neurological aspect of SARS CoV2 including the suggested mechanism
been involved. Increasingly, neurological disorders are being cited in addition to emerging experimental models with viral
involvement.

Conclusion:

There is a need for further investigation to clarify how it can lead to the onset of acute and chronic neurological
disorders, mentioning the importance of the experimental studies in neuropsychopharmacology.
HY-index: A new science-meter index
Authors:   Mathematics Department, Faculty of Education, Alexandria University, Alexandria, Egypt, Youssef Hamdy M. ,   Mechanical Engineering Department, College of Engineering and Islamic Architecture, Umm Al-Qura University, Makkah, Saudi Arabia, El-Bary Alaa A. ,   Basic and Applied Science Department, Arab Academy for Science and Technology, Alexandria, Egypt
Published: February 2021

In academic societies, it is essential to measure the efficiency of the researchers, scientists, institutions, departments, and universities by using a standard method that depends on their publications and citations. This work is devoted to constructing a new index that can measure the quality of the publications of any source mentioned above. The main goal of this new index is to fix the shortcoming of the current indices, such as the well-known h-index. Thus, we assumed a new index that is very sensitive to any change in the total number of publications, the total number of citations, and citations of each publication. The new index is called HY-index, is more sensitive to any change in the publications or the citations. The suggested data of the two authors have been discussed with various situations by using HY-index. This index has been applied to the authors of the recent paper as a real study case by using their data from SCOPUS.
Reassembling the English Novel, 1789–1919
Authors: Riddell Allen , Betancourt Michael
Published: February 2021

The absence of an exhaustive bibliography of novels published in the British Isles and Ireland during the 19th century blocks several lines of research in sociologically-inclined literary history and book history. Without a detailed account of novelistic production, it is difficult to characterize, for example, the population of individuals who pursued careers as novelists. This paper contributes to efforts to develop such an account by estimating yearly rates of new novel publication in the British Isles and Ireland between 1789 and 1919. This period witnessed, in aggregate, the publication of between 40,000 and 63,000 previously unpublished novels. The number of new novels published each year counts as essential information for researchers interested in understanding the development of the text industry between 1789 and 1919.
Inherited Kidney Complement Diseases
Authors: Lemaire Mathieu , Noone Damien , Lapeyraque Anne-Laure , Licht Christoph , Frémeaux-Bacchi Véronique
Published: February 2021

In the past 20 years, we have witnessed tremendous advances in our ability to diagnose and treat genetic diseases of the kidney caused by complement dysregulation. Staggering progress was realized toward a better understanding of the genetic underpinnings and pathophysiology of many forms of atypical hemolytic uremic syndrome (aHUS) and C3-dominant glomerulopathies that are driven by complement system abnormalities. Many of these seminal discoveries paved the way for the design and characterization of several innovative therapies, some of which have already radically improved patients’ outcomes. This review offers a broad overview of the exciting developments that have occurred in the recent past, with a particular focus on single-gene (or Mendelian), complement-driven aHUS and C3-dominant glomerulopathies that should be of interest to both nephrologists and kidney researchers. The discussion is restricted to genes with robust associations with both aHUS and C3-dominant glomerulopathies (complement factor H, complement component 3, complement factor H–related proteins) or only aHUS (complement factor B, complement factor I, and membrane cofactor protein). Key questions and challenges are highlighted, along with potential avenues for future directions.
PENDAMPINGAN ADMINISTRASI PENGAJUAN LEGALITAS SD MUHAMMADIYAH 4 KOTA BATU
Authors: Widyastuti Aviani , Jati Ahmad Waluya , Arisanti Ike
Published: February 2021

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan pendampingan dalam perbaikan dan penertiban administrasi pada salah satu Amal Usaha Muhammadiyah (AUM) di Kota Batu yaitu SD Muhammadiyah 4. Perbaikan dan penertiban administrasi yang dimaksud dalam hal ini adalah terkait dengan pengurusan ijin pendirian AUM yang selaras dengan status badan hukum AUM yaitu Nomor Induk Berusaha (NIB) dan penyeragaman Nomor Induk Wajib Pajak (NPWP). Kegiatan ini pada dasarnya akan dilakukan dalam tiga tahapan yaitu tahap pengurusan NIB, tahap Pelaporan keuangan dan perpajakan dan tahap tata kelola AUM. Akan tetapi proposal ini diajukan sebagai bentuk penyelesaian permasalahan SD Muhammadiyah 4 Kota Batu untuk tahap pertama yaitu pengurusan NIB. Penyelesaian permasalahan pada tahap pertama kegiatan ini adalah dengan menggunakan metode presentasi, pelatihan dan pendampingan serta dialog. Adapun luaran dari kegiatan pengabdian pada tahap pertama ini adalah SD Muhammadiyah Kota Batu dapat mengurus dan menyelesaikan prosedur administrasi perijinan terkait NIB serta penyeragaman NPWP.
Building interdisciplinary research teams according to the requirements of the national research evaluation system
Authors:   Department of Information Systems and Logistics, Wiechetek Łukasz ,   Faculty of Economics,   Maria Curie-Skłodowska University, Lublin, Poland
Published: February 2021

Aim/purpose – The paper explores the issue of building interdisciplinary research teams from the point of view of the evaluation requirements for Polish researchers and research units. The main aim of the paper is to determine the possibility of creating interdiscipli-nary research teams involving management and economics researchers.Design/methodology/approach – The author searched 30,404 journals. An assumption was made that team creation should reflect the evaluation requirements of several meas-urement factors of similarity between disciplines, these were duly developed. An analy-sis of the possibility of developing effective interdisciplinary teams to maximise the possible number of places for publications and points scored was performed and dis-cussed. The analysis was performed by considering all of the scored journals useful for the development of young researchers and well-regarded journals publishing original research prepared by experienced scientists.Findings – The analysis indicates that the relevant journals are not evenly spread among the various scientific disciplines examined. Considering the possibility of finding many shared journals for publication while achieving favourable interdisciplinary research outcomes and scoring a high number of evaluation points, researchers in the fields of economics as well as finance and management and quality sciences should mainly cooperate with researchers in the field of socio-economic geography and sociological sciences.Research implications/limitations – The analysis was based on the Polish national research evaluation system, which may limit the generalisation of the results. Originality/value/contribution – The results presented in the paper may be useful for researchers, research team managers and authorities who run research units and create effective research teams.
RELIGIOUS RADICALISM FRAME IN THE ONLINE MEDIA NEWS (Framing Analysis Reporting Of “ISIS” In Republika.co.id and Tempo.co)
Authors: Zamroni Mohammad , Astuti Yanti Dwi , Zuhri Achmad
Published: February 2021

This study aims to explore how the framing of Islamic radicalism through the reporting of the group "ISIS" in two online media, namely in Republika.com and Tempo.co with an impartiality perspective. The research method used is descriptive qualitative by using a discourse strategy that sees the text and its context as information that contributes to communicating the contents of the message. Primary and secondary data are obtained from news curators, online portals, and library studies. While the unit of analysis is ISIS radicalism news in Republika.co.id and Tempo.co in the period of August to December 2014 that falls within the three criteria of radicalism news, namely acts of violence, beliefs championed, old-fashioned views or rigid thoughts that underlie acts of violence using techniques framing analysis of Gamson and Modigliani models. The results showed that news about radical "ISIS" included in the category of news construction that was emotional, sadistic, provocative and without confirmation. In addition, the quality of reporting often adorns with words that appear hyperbole and bombastic, the coverage is less profound and changes in a matter of minutes. The trend of Tempo.co and Republika.co.id dramatizes and exaggerates what happens in conflict areas by using connoted language rather than language that has a literal meaning. Then it has not fulfilled the principle of impartiality of news which can be seen from the neutrality and balance of news that determines the quality of reporting.
Analisis Kadar Merkuri, Derajat Keasaman dan Faktor Risiko Kesehatan Pada Penambang Emas Tanpa Izin di Kecamatan Cempaka
Authors: Indah Meilya Farika , Agustina Norsita
Published: February 2021

Cempaka District is the largest traditional gold mining site in South Kalimantan Province. The purpose of this study was to identify levels of mercury (Hg), degree of acidity (pH) and health risk factors (age, years of service and completeness of PPE) in PETI workers in Cempaka District. The method used in this research is an observational method which is quantitative in nature with a cross-pontong approach, with a proportional difference test method. Sampling was carried out in the upstream and downstream areas. Measurement of water mercury levels was measured by means of Cold Vapor Atomic Absorption Spectrophotometry (CV-AAS) at the Industrial Research and Standardization Center (BARISTAND) in Banjarbaru City. As for the health risk factor variables using the method of observation and interviews with a questionnaire. The research sample was 40 active PETI workers. The results showed that the quality of water with mercury content exceeds the threshold, for the parameter of acidity (pH) within the norm limit of 6-9. Meanwhile, for health risk factors, PETI workers are mostly old, have worked ≥ 5 years and do not completely use PPE. Suggestions are to pay attention not to dispose of waste mercury (Hg) content into rivers. Keywords : Mercury levels ( Hg ); degrees acidity ( pH ); health risk factors; the workers

Abstrak Kecamatan Cempaka merupakan tempat penambangan emas tradisional yang terbesar di Provinsi Kalimantan Selatan. Tujuan penelitian ini adalah untuk mengidentifikasi besar kadar merkuri (Hg), derajat keasaman (pH) dan faktor risiko kesehatan (Umur, masa kerja dan kelengkapan APD) pada pekerja PETI di Kecamatan Cempaka. Metode yang digunakan dalam penelitian ini yaitu metode observasional yang bersifat kuantitatif dengan pendekatan potong lintang, dengan metode uji-beda proporsi. Pengambilan sampel dilakukan pada daerah hulu dan hilir. Pengukuran kadar merkuri air diukur dengan alat Cold Vapor Atomic Absorption Spectrophotometry (CV-AAS) di Balai Riset dan Standarisasi Industri (BARISTAND) di Kota Banjarbaru. Sedangkan untuk variabel faktor risiko kesehatan menggunakan metode pengamatan dan wawancara dengan kuosioner. Sampel penelitian adalah pekerja PETI yang aktif sebanyak 40 responden. Hasil penelitian menunjukkan kualitas air dengan kandungan kadar merkuri melebihi ambang batas, untuk parameter derajat keasaman (pH) dalam batas norma sebesar 6-9. Sedangkan untuk faktor risiko kesehatan, pekerja PETI lebih banyak berumur tua , masa kerja ≥ 5 tahun dan tidak lengkap menggunakan APD. Saran untuk memperhatikan untuk tidak membuang limbah kandungan kadar merkuri (Hg) ke aliran sungai. Kata kunci : Kadar Merkuri (Hg); Derajat Keasaman (pH); Faktor Risiko kesehatan; Pekerja PETI
Well-being in Residency: Impact of an Online Physician Well-being Course on Resiliency and Burnout in Incoming Residents
Authors: Ricker Mari , Brooks Audrey J. , Bodine Sarah , Lebensohn Patricia , Maizes Victoria
Published: February 2021

Background and Objectives: Wellness in residency has come to the forefront of national graduate medical education initiatives. Exponential growth in knowledge and skill development occurs under immense pressures, with physical, mental, and emotional stressors putting residents at burnout risk. The Accreditation Council for Graduate Medical Education requires programs to attend to resident wellness, providing the structure, environment, and resources to address burnout. This study’s purpose was to evaluate the Andrew Weil Center for Integrative Medicine online Physician Well-being Course (PWC) with incoming postgraduate year-1 (PGY-1) residents in multiple residencies across a single health care system. The PWC teaches the learner strategies for building resilience, managing stress, identifying signs of burnout, and mindfulness practices including a self-selected daily 10-minute resiliency activity (meditation, gratitude journaling, and finding meaning journaling) for 14 days.
Methods: Incoming PGY-1 residents were enrolled in PWC 1 month prior to 2018 orientation. Validated measures of resiliency, burnout and gratitude were completed pre- and postcourse. We assessed pre/postcourse changes with paired t tests. We asked participants whether they incorporated any wellness behavior changes postcourse.
Results: Almost two-thirds of the incoming trainees completed the course (n=53/87, 61%). We found significant improvements (P<.05) for resiliency and burnout (emotional exhaustion, depersonalization). Gratitude did not change. The personal accomplishment burnout scale declined. The most frequently reported wellness behaviors were in the area of sleep, exercise, and diet.
Conclusions: Resiliency, emotional exhaustion, and depersonalization improved, personal accomplishment declined, while gratitude remained the same. This project demonstrates an accessible and scalable approach to teaching well-being to incoming residents.
Brief Video-Based Suicide Prevention Training for Primary Care
Authors: Pisani Anthony R. , Cross Wendi F. , West Jennifer C. , Crean Hugh F. , Caine Eric D.
Published: February 2021

Background and Objectives: One-third of individuals who die by suicide had primary care contact in the preceding month. Primary care trainees need engaging and effective suicide prevention training that can be delivered within tight time and resource constraints. However, training is currently scarce and its effectiveness unknown. The objective of this study was to assess learner engagement, learning, self-efficacy, and perceived ability to transfer training to practice from brief video-based modules centered around visual concept mapping of suicide prevention practices.
Methods: We assigned 127 primary care trainees 21 brief instructional videos to watch. We analyzed engagement by monitoring the proportion of learners who began each video and the proportion of the video watched. We assessed knowledge and self-efficacy pre- and posttraining. Learners provided feedback on satisfaction with modules and ability to transfer training to practice.
Results: Engagement was high, with most learners watching most of each video (mean=83.2%). Increase in knowledge was large (t(131 df)=19.91, P<.001). Confidence in ability to manage suicide risk rose significantly (t(131 df)=16.31, P<.001). Perception of ability to transfer training to practice was moderate. Satisfaction with modules was high. Feedback asked for patient scenarios and practical skills examples.
Conclusions: This training successfully engaged primary health care trainees in suicide prevention education. Training transfer will be improved by adding skill demonstrations, a suicide attempt survivor perspective, and a memorable framework to assist implementation of knowledge. A new iteration incorporating these improvements is under evaluation. Variants for other health care settings are under development.
Impact of Antibiotic Selection for Prophylaxis of Left Ventricular Assist Device Surgical Infections
Authors: Nguyen Peter , Colley Peter , Sam Teena , Zyl Johanna Van , Felius Joost , Berhe Mezgebe , Meyer Dan
Published: February 2021

Surgical site infections (SSI) after left ventricular assist device
(LVAD) implantation are associated with high mortality, while surgical
prophylaxis is variable. This retrospective study included adult
patients who underwent LVAD implantation at a single center. We compared
outcomes in patients who received narrow antimicrobial prophylaxis
(cefazolin, vancomycin or both) to those who received broad
antimicrobial prophylaxis (any antimicrobial combination targeting
gram-positive and gram-negative organisms not included in the narrow
group) at 30 days and 1 year post-implantation. Cox-proportional hazards
models and log-rank tests were used for survival analysis. Among the 39
and 65 patients comprising narrow and broad groups respectively, there
was no difference in rate of SSI at 30 days (6.2% vs 12.8%, p = 0.290)
and 1 year (16.9% vs 25.6%, p = 0.435). Comparing narrow to broad
prophylaxis, the risk of mortality [HR (95% CI): 0.44 (0.15. 1.35),
logrank P = 0.14], and composite of mortality and infection was
reduced [HR (95% CI): 0.92 (0.45, 1.88), logrank P = 0.83], but did
not reach statistical significance. Most culture positive infections
were due to gram-positive bacteria (70%) and the most common organisms
were the Staphylococcus spp (47%). There were no significant
differences in the rate of SSI at 1-year (p=1.00) and mortality (p=0.33)
by device type. The rates of infection and all-cause mortality were not
different between patients who received narrow or broad prophylaxis.
This highlights an opportunity for institutions to narrow their surgical
infection prophylaxis protocols to primarily cover gram-positive
organisms.
Metastatic renal cell carcinoma complicated by right atrial thrombus
Authors: Jeelani Hafiz , Sheikh Muhammad Mubbashir , Riaz Adeel , Tahir Nayha , Jain Nikita , Ehsan Hamid , Vemireddy Lalitha
Published: February 2021

Metastasis of renal cell carcinoma to the heart is a rare event. Herein
we present a case of renal cell carcinoma presenting with progressive
fatigue, abdominal pain, and weight loss. Imaging studies revealed
complex renal mass with extension to right atrium and histopathology
confirmed the metastatic renal cell carcinoma.
Finite point method of nonlinear convection diffusion equation
Authors: Qin Xinqiang , Hu Gang , Peng Gaosheng
Published: February 2021

Aiming at the nonlinear convection diffusion equation with the numerical
oscillations, a numerical stability algorithm is constructed. The basic
principle of the finite point algorithm is given and the computational
scheme of the nonlinear convection diffusion equation is deduced. Then, the
numerical simulation of the one-dimensional and two-dimensional nonlinear
convection-dominated diffusion equation is carried out. The relationship
between the calculation result and the support domain size, step size and
time is discussed. The results show that the algorithm has the
characteristics of simplicity, stability and efficiency. Compared with the
traditional finite element method and finite difference method, the new
algorithm can attain a higher calculation accuracy. Simultaneously, it
proves that the method given in this paper is effective to solve the
nonlinear flow diffusion equation and can eliminate the numerical
oscillations.
Hyperbolization of the limit sets of some geometric constructions
Authors: Zhang Zhanqi , Xiao Yingqing
Published: February 2021

Inspired by the construction of Sierpi?ski carpets, we introduce a new
class of fractal sets. For a such fractal set K, we construct a Gromov
hyperbolic space X (which is also a strongly hyperbolic space) and show that
K is isometric to the Gromov hyperbolic boundary of X. Moreover, under some
conditions, we show that Con(K) and X are roughly isometric, where Con(K) is
the hyperbolic cone of K.
Screen transversal cauchy Riemann lightlike submanifolds
Authors: Doḡan Burçin , Şahin Bayram , Yaşar Erol
Published: February 2021

We introduce a new class of lightlike submanifolds, namely, Screen
Transversal Cauchy Riemann (STCR)-lightlike submanifolds, of
indefinite K?hler manifolds. We show that this new class is an umbrella of
screen transversal lightlike, screen transversal totally real lightlike and
CR-lightlike submanifolds. We give a few examples of a STCR lightlike
submanifold, investigate the integrability of various distributions, obtain
a characterization of such lightlike submanifolds in a complex space form
and find new conditions for the induced connection to be a metric
connection. Moreover, we investigate the existence of totally umbilical
(STCR)-lightlike submanifolds and minimal (STCR)-lightlike submanifolds. The
paper also contains several examples.
How do passenger and trip attributes affect walking distances to bus public transport stops? Evidence from university students in Greece
Authors: Tsioulianos Christos , Basbas Socrates , Georgiadis Georgios
Published: February 2021

The spatial arrangement of public transport systems seriously affects their
ridership and thus the fulfillment of sustainable transport goals. This
paper examines the case of students at Aristotle University of Thessaloniki
and investigates their perceptions regarding a critical spatial attribute of
public transport, that is, the walking distance they have to cover to/from
bus stops when they commute by bus to their campus. A questionnaire survey
was conducted to collect relevant data from 300 students and a set of
statistical inference methods was employed to explore whether
student-specific attributes relate to the walking distances they consider to
be acceptable. Empirical findings highlighted weak relationships between
user/trip specific attributes with regard to students, and their walking
distance preferences for the bus public transport services they use. The
majority of students consider that the maximum acceptable walking distance
can be higher than the standard value of 400 meters. Moreover, they would be
willing to walk more than they currently do in order to reach a bus stop
with higher service frequencies to their campus. The study concept and
findings could assist in delivering a more successful spatial design of bus
public transport systems which serve university campuses. A more sparsely
positioned network of bus stops would provide better opportunities for
personal physical activity but should not yield increased total travel
times; and they should incorporate local user expectations. Public transport
agencies could also benefit from achieving higher service speeds which, in
turn, would reduce energy consumption and operating costs.
A hypothesis on a comprehensive approach to managing the urban polycentralization of post-socialist metropolitan areas
Authors: Zhukovsky Roman
Published: February 2021

Managing the polycentralization of metropolitan areas can contribute to a
more even pace of development of builtup areas; it can also increase the
economic and temporary accessibility of urban centers. This study, attempts
to synthesize the main hypothetical provisions of a comprehensive approach
to managing the development of polycentric metropolitan areas in
post-socialist countries. It presents the necessity for modeling not only
the core city, but also the entire metropolitan area when managing
polycentralization. The study reveals the formalized stages of how a
polycentric metropolitan area evolves and presents a comprehensive analysis
on the main problems of a technological and methodological, administrative
and legal nature in managing the development of polycentric metropolitan
areas. It also highlights the significance of comprehensively developing the
transport infrastructure and the prevalence of information and
telecommunication technologies within the metropolitan area, as well as the
spatial compactness of the metropolitan areas for the polycentralization
progress. It is considered that the specific features of the post-socialist
urban process can affect polycentralization, including (post-)
suburbanization, reurbanization, and gentrification. Finally, measures are
suggested in the field of scientific research and technologies, and
municipal and regional management aimed at increasing the manageability of
developing polycentric metropolitan areas in a postsocialist urban planning
context.
Rapid Changes in Serum Testosterone in Men with Newly Diagnosed Type 2 Diabetes With Intensive Insulin and Metformin
Authors: Hu Yun , Ding Bo , Shen Yun , Yan Reng-Na , Li Feng-Fei , Sun Rui , Jing Ting , Lee Kok-Onn , Ma Jian-Hua
Published: February 2021

Objective: To investigate the effect of metformin on
testosterone levels in men with type 2 diabetes mellitus (T2DM).

Methods: Seventy men with newly diagnosed drug naïve T2DM, HbA1c >9.0% (75mmol/mol) were treated with intensive insulin pump therapy for 5
days to achieve glucose normalization. They were randomized to control (continued
on intensive insulin only) and metformin (plus metformin) groups (1:1) for one
month. Testosterone was measured at baseline, randomization, and after one-month
treatment.

Results: Total, free and
bioavailable testosterone increased significantly within 5
days (all p<0.001). After one
month, compared to controls, the metformin group had lower total (12.7 vs 15.3
nmol/L), free (0.20 vs 0.24 nmol/L), and bioavailable (4.56 vs 5.31 nmol/L)
testosterone (p all <0.05).

Conclusions: In men with T2DM,
one-month oral metformin may decrease serum testosterone levels independent of
blood glucose control. The effects of long-term metformin on testosterone in
men need further study.
Tolkemedierte gruppearbeid mellom elever med talt og tegnet språk
Authors: Berge Sigrid Slettebakk
Published: February 2021

Tilrettelegging av tolket undervisning er et aktuelt tema både innen utdanning og forskning fordi flere elever med tegnspråk velger opplæring i den ordinære skolen. Har elevene norsk tegnspråk som ett av sine språk, sier opplæringsloven §2.6 og §3.9 at de skal ha en opplæring «i og på tegnspråk». For å ivareta opplæringstilbudet har det blitt vanlig at skolene ansetter tolker som skal formidle det som sies mellom lærer og elev, og mellom elevene. Samarbeidslæring er en sentral måte å organisere undervisningen på. I denne artikkelen belyser jeg hvordan lærere kan legge til rette for tolking av gruppearbeid mellom elever med talt og tegnet språk. Analysene viser oss betydningen av at lærerne lager tydelige rammer for samtalene som oppstår når elevene arbeider med oppgaver, at de må tenke på hvordan de organiserer det fysiske læringsmiljøet og at de må sette sammen grupper der elevene er fortrolig med hverandre og tolkens tilstedeværelse. Det empiriske materialet som ligger til grunn for studien, er fra videregående skole. Funnene i studien kan imidlertid relateres til høyere og lavere skoletrinn fordi utfordringene ikke er knyttet til elevenes alder, men til generelle mønstre i tolkede samtaler mellom flere deltakere og mellom talt og tegnet språk.
English abstract
English title: Interpreted group work between sign language and spoken language learners
Facilitating interpreted teaching is a relevant topic in education and research because several pupils with sign language choose education in the mainstream school. If students have Norwegian sign language as one of their languages, the teachers are committed by law to adopt their teaching practice towards a sign language friendly learning environment and ensure that the pupils have an education “about and in sign language”. In order to safeguard the education, it has become more common for schools to employ interpreters to communicate what is being said between teacher and pupil, and between pupils. In this article I explore how teachers can facilitate interpretation of group work situations between sign language and spoken language learners. The analyses show the importance of teachers creating a clear framework for the conversations that arise when the students work with tasks, that the teachers must think about how they organize the physical learning environment and that they must put together groups of students who are familiar with each other and the interpreter’s presence. The empirical material presented is from high school level, but the findings can be related to other school levels because the basic structures of interpreted communication are the same, regardless of the age of the participants.
Kewajiban Negara Indonesia Setelah Meratifikasi International Covenant on Economic Social and Cultural Rights (ICESCR)
Authors: Itasari Endah Rantau
Published: February 2021

As an ICESCR participating country, Indonesia is bound to implement the provisions of the covenant, especially the use of the institutions in it because Indonesia does not declare a reservation and / or a declaration of the provisions of the Covenant. Five years after Indonesia ratified the covenant, namely in 2010, Indonesia was obliged to send a country report containing the progress of the implementation of the covenant to the Committee on Economic, Social and Cultural Rights. This mechanism is established by the agency / committee concerned to monitor the progress of the implementation of state obligations as stated in the agreement. This is done through various reports that the state must submit within a certain period to the committee concerned. The Committee meets periodically among itself and meetings of delegates of the state parties. During these meetings the committee assessed the report prepared by the state and asked a number of clarifying questions. After that the committee made conclusions and recommendations. Usually the committee identifies positive things that have been achieved, issues that are still crucial and certain recommendations.