bluuebunny/crossref_metadata_2025 huggingface dataset:
A CASE REPORT ON LONG TERM COMPLICATIONS OF CAUDA EQUINA SYNDROME
Authors: Padinjarethil George Shone , Sara Shaji Shiby , Varghese Mohan
Published: March 2023

Cauda Equina Syndrome (CES) is a rare emergency condition where the ends of the spinal cord, specically, the lumbar and sacral spinal nerves get
congested mostly due to disc herniation or trauma. The marked complication of CES includes bowel incontinence, bladder incontinence leading to
UTI, high grade sores in the gluteal region and saddle anesthesia. This is one among the rarest neurosurgical emergencies. The only treatment for
Cauda equina syndrome is a surgical procedure, that is, decongestion of the lumbar spinal nerves called Lumbar laminectomy. In this case report,
we shall discuss and evaluate on the long-term complications of cauda equina syndrome which includes various sectors of life. This study is done to
report on the long-term complication of cauda equina syndrome in relation to the relative Quality of Life (QoL) of patients
SCROTAL PEARL IN CHRONIC HYDROCELE: A RARE CASE ENTITY
Authors: lakshman Pappu Vamsi , Soni Mukesh
Published: February 2023

Introduction: Scrotal pearl or scrotal calculus are benign micro-calcications in the extratesticular scrotum found incidentally during
ultrasonography, operation or on clinical examination if the size is large. The aetiology and pathogenesis are unclear but linked to repeated microtrauma due to injury, inammation, infections by parasites and long-standing chronic hydroceles. They are usually of no clinical signicance and
do not change patient management. Incidence is between 1-5%. Aims And Objectives: The study aims to discuss a rare presentation of chronic
hydrocele
Objectives:
Ÿ Discuss the aetiologies and management of scrotal pearl in chronic hydrocele.
Methods Results: : We will be discussing a case of scrotal pearl in chronic hydrocele. The differential diagnosis of calcied intratesticular lesion
should be ruled out. Conclusion: Scrotal pearls are rare, with limited literature hence making it an interesting case for discussion and learning.
Automatic Deep Sparse Multi-Trial Vector-based Differential Evolution Clustering with Manifold Learning and Incremental Technique
Authors: Hadikhani Parham , Lai Daphne Teck Ching , Ong Wee-Hong , H.Nadimi-Shahraki Mohammad
Published: March 2023

Most deep clustering methods despite providing complex networks to learn better from data, use a shallow clustering method. These methods have difficulty in finding good clusters due to the lack of ability to handle between local search and global search to prevent premature convergence. In other words, they do not consider different aspects of the search and it causes them to get stuck in the local optimum. In addition, the majority of existing deep clustering approaches perform clustering with the knowledge of the number of clusters, which is not practical in most real scenarios where such information is not available. To address these problems, this paper presents a novel automatic deep sparse clustering approach based on an evolutionary algorithm called Multi-Trial Vectorbased Differential Evolution (MTDE). Sparse auto-encoder is first applied to extract embedded features. Manifold learning is then adopted to obtain representation and extract the spatial structure of features. Afterward, MTDE clustering is performed without prior information on the number of clusters to find the optimal clustering solution. The proposed approach was evaluated on various datasets, including images and time-series. The results demonstrate that the proposed method improved MTDE by 18.94% on average and compared to the most recent deep clustering algorithms, is consistently among the top three in the majority of datasets. Source code is available on Github: https://github.com/parhamhadikhani/ADSMTDE_Clustering. 
The Hittite King as Administrator of the Land
Authors: Torri Giulia
Published: March 2023

In recent years archaeological investigation has made an important contribution for ascertaining the possible relationship between the center of the kingdom, namely the king and his capital city, and the regions at the core of the kingdom in different periods of Hittite history. The empire was not a monolithic entity but a complex web of interactions. In this frame the Hittite king emerges in his several roles. In this study I have chosen to focus on the king’s administrative role and the way in which he was present in the territory through a controlled system of land allocation.
Ambienti innovativi di apprendimento
Authors: D'Anna Oriana
Published: February 2023

Il seguente articolo si propone di analizzare quattro ricerche svolte sul campo relative all’utilizzo della metodologia del Digital Storytelling (DST) nelle pratiche didattiche e nella formazione iniziale dei docenti in prospettiva inclusiva. Si tratta degli studi svolti dai ricercatori Baschiera e Banzato dell’Università degli studi Ca’ Foscari di Venezia, di Lazzari dell’Università di Bergamo e di Petrucco dell’Università di Padova. I risultati delle ricerche suddette evidenziano le potenzialità della metodologia e la sua applicabilità con alunni con Bisogni educativi speciali (BES) e l’efficacia del metodo per l’acquisizione di competenze digitali nella formazione iniziale dei docenti per la costruzione di ambienti di apprendimento innovativi nell’ambito della Media Education e della didattica speciale.
DAL GAME-BASED LEARNING AI SERIOUS GAMES: ALCUNE PROSPETTIVE PER L’APPRENDIMENTO MEDIATO DALLA TECNOLOGIA DIGITALE
Authors: Marco Ciziceno
Published: February 2023

In the last years, serious games have become popular in media education as they are useful tools in engaging, motivating, and helping students learn. However, few studies investigate the long-term effects of game-based learning, and many scholars declare themself skeptical about the learning mediated by digital technology. This paper reflects on the importance of new media and serious games for young people belonging to the Net Generation as defined by Prensky. In particular, I support the idea that game-based learning reflects a broader change in our society, coinciding with the rise of the phenomenon of Gamification and the Homo Ludens paradigm. Apart from the limitations of technology-mediated learning, the paper outlines possible and new directions of serious games in educational and social work contexts.

 

I serious games sono diventati negli ultimi anni degli strumenti diffusi nel campo dell’educazione poiché ritenuti utili a invogliare, motivare e supportare l’apprendimento degli studenti. Tuttavia, pochi studi indagano gli effetti a medio-lungo termine del game-based learning e molti studiosi si definiscono critici rispetto all’apprendimento mediato dalla tecnologia digitale. Il presente contributo riflette sull’importanza che i new media e i serious games hanno per i giovani appartenenti alla Net Generation come definita da Prensky. In particolare, si vuole supportare l’idea che il game-based learning è il riflesso di un cambiamento più ampio avvenuto nella nostra società che coincide con l’affermarsi del fenomeno della Gamification e il paradigma dell’homo ludens. Senza voler sottacere i limiti dell’istruzione mediata dalla tecnologia, il lavoro delinea possibili e nuovi direzioni del serious game in contesti educativi e di intervento sociale.
الذكاء,التنافسي,ودوره في,تمكين,الموارد,البشرية
Authors: حسن بشار , الذبحاوي عامر
Published: March 2023

يهدف البحث إلى الكشف عن العلاقة والتأثير بين الذكاء,التنافسي من خلال أبعاده الفرعية,وتمكين,الموارد البشرية,على مستوى عينة من العاملين في مستشفى الحياة الأهلي، انطلاقاً من مشكلة رئيسة,شُخصت بعدة تساؤلات تضمنت مدى إدراك العلاقة,والأثر بين المتغيرات ميدانياً، ولتجذير الأسس المعرفية,اعتمد البحث أنموذج (Strauss&Dutoit,2010) لقياس الذكاء,التنافسي الذي يتكون من أربعة أبعاد: (التخطيط، التجميع، التحليل، الاتصال) وأنموذج (Blanchard et al.,1999) لقياس,تمكين,الموارد,البشرية,الذي تضمن أربعة أبعاد رئيسة (الحرية والاستقلالية، مشاركة المعلومات، فرق العمل، القوة التنظيمية).

وقد اعتُمدت الاستبانة كأداة رئيسة في جمع بيانات,ومعلومات البحث فضلاً عن بعض المقابلات الشخصية التي تمت استناداً الى فقرات الاستبانة مع أفراد العينة,الذين تمثلوا بمجموعة من القادة,والتابعين في مستشفى الحياة الأهلي عينة البحث بلغ عددهم (165) فرداً توزعوا على أقسام وشعب المنظمة,المبحوثة (الشعبة الادارية، الحسابات، المختبرات الطبية، الممرضين، الصيادلة، الاطباء) بالاضافة الى مجلس,الادارة.

ولغرض التحليل والمعالجة الإحصائية,اعتمد البحث على اختبار التوزيع الطبيعي لبيانات البحث، ومجموعة من المقاييس الإحصائية الوصفية، وتم استخدام اختبارات بنائية أساسية,لصدق المقاييس المعتمدة كأختبار اساليب الاتساق الداخلي,والتي تتضمن (الموثوقية المركبة، الفا كرونباخ، اختبار متوسط التباين المستخرج، التحليل العاملي التوكيدي)، وتم قياس علاقة التأثير لتقدير معامل التأثير,ومعامل التحديد، وقد استخدمت هذه الأساليب عن طريق البرامج الإحصائية            (SPSS V.22. Smart Pls).

وقد تم التوصل من خلال البحث إلى استنتاجات عديدة كان من أهمها اهتمام العاملين في مستشفى الحياة الأهلي عينة البحث بالذكاء,التنافسي الذي يعد من المفاهيم الحديثة نسبياً التي تعبر عن القيمة المضافة المعتمدة في تطوير منظمات الأعمال,والتخطيط,الاستراتيجي وأبحاث,السوق ويعمل على ايصال المعلومات المهمة للإدارة,العليا عن ما ينوي المنافسين فعله ويمكنّها من اتخاذ القرارات,الاستراتيجية الخاصة بفهم البيئة الخارجية، ويسهم في تطوير المعرفة,التنظيمية بالسوق ويحسن من جودة خدماتها,ومنتجاتها ويضمن تحسين الاداء وبالتالي يحقق الميزة,التنافسية وذلك بالاعتماد على تمكين,الموارد,البشرية,الذي يكسب العاملين المرونة والتكيف,والاستجابة الفعالة في التعامل مع بيئة العمل الداخلية من جانب,ومع الزبائن من جانب اخر دون الرجوع الى الادارة كون منهج,التمكين,للمورد,البشري يساعد في تحسين جودة العلاقات بين الموظفين والزبائن ويجعل تركيز الادارة,العليا منصباً على القضايا الاستراتيجية طويلة الامد,وعدم انشغالها بالأمور الروتينية .
PESA Australia Business Environmental Review 2021: Oil & Gas Industry at a Pivotal Point in the Energy Transition
Authors: Bell Candice
Published: February 2023

With a backdrop of energy transition and an accelerating need to decarbonise, the oil and gas business environment was complex and conflicted through 2021. The complexity of the energy transition was continually highlighted by academia and international agencies. While asserting gas and LNG as a fuel critical to the energy transition, they continued to warn that the transition away from fossil fuels is not occurring fast enough to arrest catastrophic climate change. International cooperation culminating at COP26 somewhat faltered in the face of the immense challenges the energy transition poses.
Intellectual Capital for Exploration is Running on Fumes
Authors: Granger Dale
Published: February 2023

The Federal Government’s acknowledgement of ever encroaching east coast gas shortages, compounded with a looming supply squeeze confronting future LNG export delivery and the scarcity of skilled explorationists to reverse the decline, has produced a near-perfect storm for the Australian hydrocarbon industry.
PENDIDIKAN AKHLAKUL KARIMAH KELUARGA PERSPEKTIF MUHAMMAD BIN UMAR AN-NAWAWI DALAM KITAB UQUDULLUJAIN
Authors: Taufik  , Ghazali
Published: February 2023

Tulisan ini meneliti tentang akhlakul karimah keluarga Muhammad Bin Umar An-Nawawi Dalam Kitab Uqudullujain. Pendidikan dapat diartikan sebagai segala sesuatu yang mengalami  proses perubahan ke arah yang lebih baik. Akhlak  adalah  sifat  yang  sudah  tertanam  dalam  jiwa  yang  mendorong  perilaku  seseorang  dengan  mudah  sehingga  menjadi  perilaku  kebiasaan.  Jika  sifat  tersebut  melahirkan  suatu  perilaku  yang  terpuji  menurut  akal  dan  agama  dinamakan  akhlak  baik  ( akhlak mahmudah). Sebaliknya, jika ia melahirkan tindakan yang jahat, maka disebut  akhlak  buruk  (akhlak  mazmumah).  Jika melihat keadaan suami-istri yang sekarang mereka sudah lupa dengan kewajiban mereka dalam berkeluarga dan mereka lupa akan dosa yang mereka lakukan. Metode penelitian yang digunakan dalam tulisan ini adalah Literasi atau Kepustakaan. Penelitian ini bertujuan untuk menguji secara empiris variable-variabel dalam penelitian yang telah dirumuskan dalam rumusan masalah, yaitu mengetahui tentang Akhlakul Karimah Keluarga Perspekti Nur Muniri Ismail. Di dalamnya terdapat upaya mendeskripsikan, mencatat, analisis dan menginterpretasikan kondisi yang sekarang ini terjadi atau ada. Dengan kata lain penelitian ini bertujuan untuk memperoleh informasi informasi mengenai keadaan yang ada. Hasil penelitian menunjukkan bahwa: 1) akhlakul klarimah adalah sikap dan prilaku seoarang istri atau suami dalam keluarga sehingga menjadi  sakinah mawaddah warahmah. ; 2) cara pengembangann akhlakul karimah dalam keluarga tidak hanya dilakukan oleh istri namun juga dilakukan oleh suami sehingga sempurnalah kelurga yang dibangun.
Evidence-Based Medicine and Patient-Centred Care
Authors: Ugar Edmund Terem
Published: March 2023

Proponents of Evidence-Based Medicine (EBM) argue that EBM’s approach to medicine promotes good clinical decisions while it escapes adverse issues such as implicit bias. However, EBM approaches the causation of diseases from a homogenous standpoint; that is, EBM overgeneralises evidence and the intervention measures it provides. As a result, proponents of Patient-Centred Care (PCC) allude that the strictness of EBM towards evidence impairs it from considering case-by-case treatment of patients but a generalised method of intervention. Given this problem, I argue that EBM cannot be considered a medical approach to practising medicine and conducting medical research that is in the best interest of individual patients, especially patients that prefer alternative interventions other than the methods of EBM. I conclude by drawing from the best features of EBM and PCC to create an alternative that accommodates the interests of both EBM and PCC patients.
Pemanfaatan Media Pembelajaran Berbasis Multimedia di Era Revolusi Industri 4.0 bagi Siswa dalam Meningkatkan Hasil Belajar di SD Negeri Duren Kecamatan Sumowono Kabupaten Semarang
Authors: Astuti Eny
Published: March 2023

Kegiatan pembelajaran pada siswa kelas 1 SD Duren kecamatan Sumowono kabupaten Semarang aktivitas siswa dalam proses pembelajaran dan hasil belajar siswa belum maksimal. Tindakan yang dilakukan untuk memecahkan permasalahan agar dapat meningkatkan aktivitas dan hasil belajar siswa serta performansi guru adalah dengan memanfaatkan media pembelajaran berbasis multimedia di era revolusi industri 4.0. Penelitian ini menggunakan rancangan Penelitian Tindakan Kelas (PTK) yang mengacu pada model Siklus PTK Penelitian dilakukan dalam tiga siklus meliputi tahap perencanaan, tahap pelaksanaan tindakan dan pengamatan, serta tahap refleksi. Jenis data yang digunakan berupa data kuantitatif dan kualitatif. Hasil penelitian yang diperoleh berupa hasil tes dan non tes. Data hasil tes merupakan data hasil perolehan tes formatif pada tiap pertemuan,. Sedangkan data hasil non tes merupakan data hasil lembar pengamatan. Nilai rata-rata kelas pada hasil tes formatif siklus I rata-rata mencapai 71 meningkat pada siklus II menjadi 80,5 dan di silkus 3 meningkat Kembali menjadi 92,83 dengan peningkatan ketuntasan belajar klasikal dari 50% menjadi 83% dan pada siklus III menjadi 100% Aktivitas belajar siswa selama proses pembelajaran pada siklus I mencapai 66,5% meningkat pada siklus II menjadi 74% dan pada siklus III menjadi 85 % mencapai kriteria aktivitas belajar sangat tinggi. Perolehan nilai performansi guru melalui siklus I mencapai  rata-rata 95 meningkat pada siklus II  mendapat rata-rata 96, dan meningkat Kembali pada siklus 3 menjadi 97 Disimpulkan dan pada tahap  memanfaatkan media pembelajaran berbasis multimedia di era revolusi industri 4.0 dapat meningkatkan hasil belajar siswa di SD negeri Duren Kecamatan Sumowono, Kabupaten Semarang.
Online Learning Implementation in English Class at SMP Mutiara Singaraja During Pandemic Covid-19
Authors: Febrin Sabrina , Agustini Dewa Ayu Eka , Pratiwi Ni Putu Astiti
Published: March 2023

The study aims to describe how the implementation of online English learning with its difficulties and strategies used to deal with those difficulties at SMP Mutiara Singaraja. Researcher used descriptive qualitative research design. There was a total of twenty-seven participants, on SMP Mutiara Singaraja. Observation sheets, questionnaires, and interviews were used by researcher as data collection instruments. The results showed that the implementation of online learning at SMP Mutiara Singaraja has been conducted properly followed the Ministry of Education and Culture's guidelines, but not strictly. Even though online learning has been running for more than a year, there are still some difficulties experienced by both teachers and students. Fortunately, over the time EFL teachers and students had found their own strategies to deal with those difficulties, so they can conduct the online learning effectively.
ИСПОЛЬЗОВАНИЕ ФИТОМЕЛИОРАНТОВ КАК СПОСОБ ПРЕДОТВРАЩЕНИЯ ОПУСТЫНИВАНИЯ ТЕРСКО-КУМСКОЙ НИЗМЕННОСТИ
Authors: Терекбаев А.А. , Баитаев М.О. , Магомадов М.А.
Published: March 2023

Решение проблемы опустынивания – задача глобального масштаба, которая касается также и отдельно взятых регионов. В статье говорится о состоянии растительного покрова Терско-Кумской низменности Чеченской Республики, о протекающих здесь процессах опустынивания. Предлагается проведение фитомелиорации для предотвращения опустынивания. Рекомендуются перспективные для закладки защитных лесополос виды деревьев и кустарников, а также виды травянистых растений для подсева в растительные сообщества с целью улучшения устойчивости песчаных почв к ветровой эрозии, стабилизации песков и улучшения кормовых качеств пастбищ.
A STUDY ON IMPACT OF MOBILE PAYMENT WITH SPECIAL REFERENCE TO YOUTHS
Authors: Prof. Satyajitsinh Gohil  , Khushbu Vinchhi  , Neha Yewale
Published: March 2023

Mobile payments are becoming increasingly popular as consumers become accustomed to the technology and merchants offer contactless transactions. Indian mobile payments are expected to grow five times by 2025. Digital payments have a major impact on the Indian economy. Government efforts to make India cashless are going well, but it will take time to become completely cashless due to other challenges. This study examines the impact of smart phones in mobile payments, their acceptability, and the impact of age in online payment methods.This research is based on Descriptive Research and uses Survey and Questionnaire methods for data collection. Statistical tools used include Chi-Square test, case processing, and data analysis.
KEYWORDS: Mobile payment, Payment behaviour, Digital payment, UPI.
A COMPARATIVE ANALYSIS OF CUSTOMER SATISFACTION OVER E-BANKING SERVICES OF PUBLIC SECTOR AND PRIVATE SECTOR BANKS
Authors: Satyajitsinh Gohil  , Raychada Bansari Pravinbhai  , Akshita Ruiwale
Published: March 2023

In todays scenario, dynamic changes in the banking sector have brought competition in winning and maintaining existing customers. Presently, banks have realized the importance of appealing to new customers is far more important than retaining existing customers of the banks, for the same cause banks are emphasizing more over customer satisfaction in providing competitive services. A comparative analysis of customer satisfaction levels in public sector banks and private sector banks has given the pathway to banks in magnifying the customers demand for comparative premium-quality services and products offered with a minimum waiting period. This research paper showcases the impact of e-banking services offered by banks to customers to avail maximum benefits. The study also identifies that e-banking services are improved versions of traditional banking systems and services because customers prefer technically sound banks as well as bankers rather than traditional banker and banking systems. The study aims to evaluate the e-banking services offered by both types of banks, including user-friendliness, security, range of services, and accessibility., and multiple services like ATMs, NEFT, Debit cards Credit cards, mobile banking
KEYWORDS:- ATMs (Automatic teller Machines), NEFT (National Electronic Fund Transfer) Debit Cards, Credit Cards.
The EU Cyber Resilience Act – An appraisal and contextualization
Authors: Burri Mira , Zihlmann Zaira
Published: March 2023

The article discusses the Commission’s Cyber Resilience Act proposal of 15 September 2022 and provides an overview of its provisions as well as a critical assessment of the most pertinent aspects related in particular to its risk-based approach, varying regulatory burden across actors and products, and its scope of application. The article further seeks to contextualize the CRA by identifying the drivers of its adoption against the broader picture of EU’s role and aspirations in the area of cybersecurity and its proactive legislative efforts in the broader digital domain.
TANGGUNG GUGAT BALAI LELANG TERHADAP PENJUALAN OBJEK LELANG SECARA ONLINE
Authors: Erniyati Erniyati , Susilawati Susilawati
Published: March 2023

Keberadaan Balai Lelang yang melakukan penjualan objek lelang melalui online merupakan sesuatu yang sangat diminati masyarakat, terlebih dengan usaha lelang, maka perlu adanya kepastian hukum dalam suatu kontrak elektronik, hal tersebut menyangkut tanggung gugat Balai Lelang dikarenakan pelaksanaan objek lelang secara online tentu tidak dapat terhindarkan seperti wansprestasi yang menyebabkan kerugian bagi pemenang lelang.
Dengan menggunakan metode penelitian yuridis normatif dapat diketahui bahwa proses lelang secara online yang dilakukan oleh Balai Lelang dimulai dari pemohon lelang mengajukan permohonan penjualan, pengumuman lelang, pendafatar calon pembeli lelang, penyetoran jaminan/uang deposito, penawaran objek lelang, mengumumkan pemenang lelang, pembayaran lelang dan menginginkan barang hasil lelang. Balai Lelang bertanggung gugat atas penjualan objek lelang secara online jika Balai Lelang tidak melaksanakan prestasinya dengan baik dimana Balai Lelang tidak memberikan informasi secara benar, jelas dan jujur mengenai kualitas dan spesifikasi objek lelang di website Balai Lelang sehingga apabila terdapat kecacatan terhadap barang yang dikirim ke pemenang lelang, keterlambatan pengiriman barang hasil lelang, adanya iktikad kurang baik dari Balai Lelang serta adanya ketidaksesuain barang dengan dokumen objek lelang maka pemenang lelang berhak untuk mengajukan gugatan kepada Balai Lelang untuk meminta ganti rugi ataupun pembatalan pembelian.
Kata Kunci: Tanggung Gugat, Objek Lelang, Online
Neuroprotective agents in acute ischemic stroke
Authors: Chia Grace YY , Yeo Selvie , Ho Jamie SY , Jou Eric , Yeo Leonard LL , Tan Benjamin YQ
Published: March 2023

Acute ischemic stroke (AIS) is the leading cause of disability and one of the top causes of mortality worldwide. The current standard of care is reperfusion therapy including intravenous thrombolysis (IVT) and thrombectomy. However, these treatments have limitations as they have a limited therapeutic window. Hence, there is a vital need to develop neuroprotective agents to prevent brain injury, extend the reperfusion window, improve mortality, and reduce disability in AIS patients. Neuroprotective agents work by counteracting the detrimental biochemical and molecular events that result in irreversible ischemic damage. Numerous preclinical studies and clinical trials have been done on different agents. Thus far, all have been definitively unsuccessful in large trials. Currently, there are several challenges in translation from animal studies to human trials. It is important to understand the current evidence as well as past challenges in the development of neuroprotective strategies in AIS in order for a more strategic selection of agents to be studied, improve study designs and thus contribute to the development of effective neuroprotective agents. Newer agents have shown promise in neuroprotection, and human trials are ongoing. In this review, the mechanisms of action of different families of neuroprotective agents were discussed. The evidence for the efficacy of different drugs in each family of neuroprotective agents was also evaluated and the current research landscape in neuroprotection for AIS was summarized. The past challenges and limitations in clinical trials and proposed possible ways to address these issues were highlighted.
Research progress in molecular pathology markers in medulloblastoma
Authors: Zhou Zixuan , Zhu Bingxin , Meng Qingming , Zhang Tong , Wu Yihao , Yu Rutong , Gao Shangfeng
Published: March 2023

Medulloblastoma (MB) is the commonest primary malignant brain cancer. The current treatment of MB is usually surgical resection combined with radiotherapy or chemotherapy. Although great progress has been made in the clinical management of MB, tumor metastasis and recurrence are still the main cause of death. Therefore, definitive and timely diagnosis is of great importance for improving therapeutic effects on MB. In 2016, the World Health Organization (WHO) divided MB into four subtypes: wingless-type mouse mammary tumor virus integration site (WNT), sonic hedgehog (SHH), non-WNT/non-SHH group 3, and group 4. Each subtype of MB has a unique profile in copy number variation, DNA alteration, gene transcription, or post-transcriptional/translational modification, all of which are associated with different biological manifestations, clinical features, and prognosis. This article reviewed the research progress of different molecular pathology markers in MB and summarized some targeted drugs against these molecular markers, hoping to stimulate the clinical application of these molecular markers in the classification, diagnosis, and treatment of MB.
Estudio bibliométrico sobre la producción científica en el campo de tecnología educativa
Authors: Castellanos Ramírez Juan Carlos , Parra Encinas Karla Lariza
Published: March 2023

This paper analyzes the scientific production published by three journals focused on Educational Technology (ET). A bibliometric study was carried out considering indicators of production, authorship and thematic lines developed between 2011 and 2021. The results highlight that the current production of articles on ET is greater than a decade ago and is mainly generated by researchers from Spanish and Mexican universities. The scientific production has been developed around 13 thematic lines. As can been seen, some thematic lines demand more attention and coverage within the research agenda.
Aproximación metodológica para un estudio científico bio-bibliográfico
Authors: González Freire José Manuel
Published: March 2023

According to the Dictionary of the Royal Spanish Academy defines “Bio-bibliography” as the “Biography of a writer with an enumeration of his works”. But in reality it is much more than that definition. It is a methodological, systematic and scientific study before birth, during and after the death of the author of the study. For many it is the study of life, biography, their professional life, their academic life, their family life, their travels, the truth is that it is this and much more at a synchronous moment in history.
Modelos de trabajo para aprender a emprender en periodismo
Authors: Peinado-Miguel Fernando , Rodriguez-Barba Dolores
Published: March 2023

The objective is to recognize a methodology to reinforce the transversality and globalization of applicable academic experiences in the Faculty of Journalism of the UCM. Work has been done on the Journalistic company subjects of the Degree in Journalism based on "Learning to undertake", through soft derived from the Learning Pyramid that provides students with sufficient qualities to undertake in communication. The results reinforce the need for an entrepreneurship center that facilitates monitoring of the best communication projects to guide them towards launchers such as Compluemprende.
Estrés en pequeños empresarios en el marco de la pandemia
Authors: Cárdenas Ortiz Luis Carlos
Published: March 2023

This research focuses on knowing the levels of stress in small entrepreneurs from Barranquilla in the framework of virtual economic activity due to the confinement in Colombia, under an analytical perspective, considering testimonies of entrepreneurs and also, the detection of cases of entrepreneurs. who require psychological attention or a complex assessment, or who may present symptoms of stress.
Hemorrhagic cerebral complications on the background of therapy with clopidogrel in patients with ischemic stroke with CYP2C19*17 polymorphous carriage: a clinical case
Authors: Sychev D. A. , Kitaeva E. Yu. , Shprakh V. V. , Mirzaev K. B.
Published: March 2023

Objective. To demonstrate on a clinical example the importance of conducting pharmacogenetic testing in patients with ischemic stroke receiving clopidogrel in order to identify the polymorphic carriage of CYP2C19*17 (C806T, rs12248560). Materials and methods. A clinical and laboratory examination of 121 patients with ischemic stroke was carried out, the CYP2C19*17 polymorphism (C806T, rs12248560) associated with an increase in the effectiveness of clopidogrel, low residual platelet reactivity, and an increased risk of bleeding was determined. Carriage of polymorphic markers was determined by real-time polymerase chain reaction. Results and conclusion. In two patients (1.7 %), carriers of polymorphic markers CYP2C19*17, hemorrhagic cerebrovascular complications were detected on the background of clopidogrel. Gastrointestinal bleeding, as well as other complications of antiplatelet therapy, are not registered in practice
MSU-Main Selected Civic Welfare Training Service Students’ Challenges in Online Distance Learning and their Academic Performance
Authors: C. Viray Marecon , C. Bag-ao Brian Ven , Jean V. Consistente Mary , Barredo Elmer
Published: February 2023

The main point of this study is to know their academic performance of the Civic Welfare Training Service Students in the online distance learning It partially sought to answer the following question; What is the demographic profile of the respondents?; What are the challenges of Online Distance learning among MSU-Main CWTS-students in terms of learning modality, financial circumstances, internet connection; What is the academic performance or Cumulative Grade Point Average (CGPA) of the students?; and Is there any relationship between the challenges of the student in Online Distance Learning and academic performance? Based on the data that was gathered, it was found that there was a significant relationship between the challenges encountered in the online distance learning and respondents' academic performance. The way you cope with the new delivery of instructions of the new normal is a sign of progress in academic performance. Thus, there is really a tremendous effect on academic performance if the learners already aware of the learning modality they have, but your academic performance only depends on the learner's ability to perform based on the criteria set by the teacher. Furthermore, challenges in online distance learning affects the academic performance of the student, while academic performance can't affect the online distance learning, thus it is very important to know the modality, learning styles of the learners in the online distance learning to get a high academic performance.
Caracterización y clasificación del fondo en el arrecife rocoso La Sorpresa (Baja California Sur, México) implementando métodos de interpolación espacial.
Authors: Del Pino -Machado Arturo , Borges-Souza José Manuel , Urcádiz-Cázares Francisco Javier , Cruz-Escalona Víctor Hugo , Martínez-Flores Guillermo , Ornelas-Vargas Arelly Ornelas-Vargas
Published: March 2023

La clasificación ambiental representa uno de los primeros pasos en el desarrollo de cualquier tipo de estudio sobre una región en particular. El uso del mapeo del hábitat se ha adoptado cada vez más para representar las características del medio pues permite identificar regiones homogéneas basadas en características únicas. La Sorpresa es un arrecife rocoso altamente heterogéneo, sin embargo, las caracterizaciones realizadas hasta el momento no han capturado dicha propiedad. El objetivo del presente estudio es desarrollar un producto cartográfico apegado a la manifestación espacial del hábitat en este arrecife rocoso. Para ello se llevó a cabo un muestreo en el que fueron obtenidos datos del entorno bentónico útiles para caracterizar la zona, al interpolar los valores de porcentaje de las coberturas abióticas y bióticas. En el presente trabajo se demostró que el uso de datos puntuales obtenidos a partir de censos visuales junto con los métodos de interpolación, resultaron ser una estrategia eficaz, con un buen desempeño para la caracterización de los arrecifes. Además, se conformaron los mapas de hábitats de la zona. El método interpolación Distancia Media Ponderada (IDW) mostró mayor fidelidad para representar las características del ambiente. Gracias a este, fue posible comprobar que el arrecife presentó elevada heterogeneidad de hábitats. De manera general el arrecife rocoso presenta una composición con tepetate y las rocas como los sustratos duros predominantes en el área, en estos se soporta la cobertura de algas coralinas, coral y macroalgas.
Bremsklotz ist auch die Verfahrensdauer
Authors: Genath Bernd
Published: February 2023

Am 11. Januar diskutierte der Deutsche Bundestag den von der Bundesregierung vorgelegten Monitoringbericht zum Thema „Erneuerbare Energien 2030“. Erreichen wir bis 2030 die angestrebten 750 Terawattstunden aus grüner Energie? Beim derzeitigen Ausbautempo fällt die Antwort eindeutig aus.
Mental States in Teenagers with Mental Retardation during Examination Sessions
Authors: Карпушкина Н.В. , Конева И.А. , Семенова Л.Э.
Published: March 2023

В статье рассмотрены особенности психических состояний подростков с задержкой психического развития в период сдачи экзаменов, а также подходы к осуществлению их психолого-педагогического сопровождения в соответствии с обнаруженными особенностями. Раскрыта возрастная специфика эмоциональной саморегуляции подростков и ее типологические особенности, характерные для лиц с ограниченными возможностями здоровья, а также ведущие психические состояния подростков, имеющих норму психического развития и отклоняющееся развитие. Выявлено влияние биологических и психологических, личностных факторов на формирование эмоциональной саморегуляции у подростков с задержкой психического развития. Обоснована важность проведения целенаправленной работы со школьниками с задержкой психического развития с целью коррекции нарушений саморегуляции. Доказана необходимость разработки программы коррекции саморегуляции подростков с задержкой психического развития с учетом особенностей их психических состояний, которая должна включать в себя два блока: диагностику психических состояний в период сдачи экзаменов и коррекцию негативных психических состояний у подростков с задержкой психического развития. Сформулированы аргументированные, обоснованные выводы о том, что подростки с задержкой психического развития имеют особенности психических состояний в период сдачи экзаменов, а также индивидуально- стилевые особенности саморегуляции.

The article treats mental states experienced by teenagers with mental retardation during examination sessions. It also focuses on various approaches to providing psychological and pedagogical support. The article focuses on the peculiarities of mentally retarded teenagers’ emotional self-regulation as well as on mental states characteristic of teenagers with mental retardation. The article deals with the impact biological, psychological and personality-related factors produce on the formation of mentally-retarded teenagers’ emotional self-regulation. The authors underline that in order to correct teenagers’ self-regulation, it is important to constantly provide psychological and pedagogical support for schoolchildren with mental retardation The authors underline the importance of improving mentally-retarded teenagers’ self-regulation taking into consideration their mental states, i.e. diagnosing mental states experienced by teenagers during examination sessions and improving their mental health. The article maintains that teenagers with mental retardation experience negative mental states during examination sessions and experience problems with self-regulation.
Evaluación de componentes de rendimiento en frijol (Phaseolus vulgaris L.) Junio León producido con diferentes tratamientos de fertilización orgánica
Authors: Luna Modesto Luis Gerardo , Machuca Fajardo Luis Daniel , Cisneros López Hugo Cesar , Jiménez Hernández Yanet
Published: March 2023

La fertilización de fondo modifica el comportamiento del cultivo y altera procesos fisiológicos como la polinización, abscisión de órganos reproductivos, aborto de semillas, así como procesos morfológicos (tamaño de hoja, numero de ramas y altura de planta) teniendo repercusión directa sobre el rendimiento de grano.
En el Instituto Tecnológico de Roque, durante el ciclo primavera-verano 2022, se estableció un ensayo con el objetivo de registrar el rendimiento y sus componentes en la variedad de frijol(Phaseolus vulgaris L.) Junio León bajo manejo con  cuatro fertilizantes orgánicos como: ácidos húmicos y fúlvicos(T1), Micorrizas(T2), Trichoderma harzianum(T3), y algas marinas(T4); se usó un diseño experimental en bloques al azar con cuatro repeticiones; teniendo como parcela útil los dos surcos centrales  de cuatro surcos de 5 m de longitud, separados a 0.75 m.
Al tiempo de cosecha, se colectaron tres muestras por tratamiento y por repetición, se registró el número de vainas por planta, granos por vaina; peso de 100 semillas (g) y rendimiento total (g/m2). El análisis de varianza no mostró diferencias significativas entre fertilizaciones; la comparación de medias con la prueba DMS (0,05) indicó que las mejores fertilizaciones fueron los ácidos húmicos y fúlvicos, así como Trichoderma harzianum las cuales presentaron mayor cantidad de vainas (46) y más rendimiento de grano (52.2 g/m2) bajo condiciones de riego, temperatura promedio (23,9 °C) y sin presencia de enfermedades.
Análisis de la tendencia al emprendimiento en estudiantes del Instituto Nelson Torres del cantón Cayambe
Authors: Carvajal Mariana De Jesús , Márquez Wilson Alexis , Morales Yeny Patricia , Abalco Darwin , Garzón Alejandro Wilfrido
Published: March 2023

Determinar los factores que influyen en la iniciativa y desarrollo de emprendimientos mediante la identificación de las condiciones socioeconómicas y laborales en las que se encuentran los estudiantes del Instituto Superior Tecnológico Nelson Torres, reconociendo además las necesidades más latentes. La presente investigación tuvo un enfoque cualitativo y cuantitativo, dado a que se procesó información estadística, las estrategias utilizadas fue la recolección de información fidedigna, proveniente de fuentes primarias, para ello, se utilizó la técnica de la encuesta aplicada a una muestra de estudiantes de todas las carreras, dando lugar a la obtención de datos reales. Los resultados obtenidos han permitido conocer la perspectiva de los estudiantes de la institución respecto a la idea de emprender y la predisposición de llevar a cabo una idea de negocio, sin embargo, la carencia de fuentes de financiamiento es una de las mayores limitantes.
La importancia de implementar especializaciones en la carrera de aeronáutica como estrategia de inserción laboral
Authors: Mamani Chuquimia Oscar
Published: March 2023

El articulo reflexiona y analiza los resultados de una encuesta realizada a estudiantes de la carrera de aeronáutica de la Universidad Mayor de San Andrés, sobre la importancia y necesidad de complementar los estudios básicos de su currículo actual, considerando las especialidades existentes dentro la normativa aeronáutica como estrategia en la inserción laboral en el campo aeronáutico de nuestro país. Se plantea entonces, a partir de concepciones de especialidad definidas por las regulaciones universitarias en comparación con la definición utilizada por la autoridad de regulación de aeronáutica civil, un punto que satisfaga ambos a partir de conocer y comprender el problema a partir de una investigación descriptiva, aplicando una encuesta debidamente validada se obtienen importantes percepciones de la muestra de estudiantes que claramente conocen el beneficio de obtener una licencia aeronáutica y las ventajas que significan en la complementariedad de su título de técnico superior o licencia ruta, así mismo en el campo aeronáutico el contar con una licencia aeronáutica significa contar con un requisito indispensable para ejercer un puesto de trabajo de especialidad en la industria aeronáutica, que sumando a una titulación profesional, se convierte en estos momento un perfil competente en el ámbito laboral.
A STUDY ON POPULARITY OF READY TO EAT FOOD PACKETS AMONG WOMEN OF AHMEDABAD CITY
Authors: Gajjar Dharti H.
Published: February 2023

Today, most societies are made up of nuclear families where most probably, the Women (mother) of the house are employed. Women purchase Ready to Eat Food Packets because it saves their time & they found them more delicious than Home Made food. Most Women were not read information written on Ready to Eat Food Packets while purchasing like manufacturing date, expiry date, ingredients, Veg.-Non Veg. Symbol, etc. This shows that they hadn’t any knowledge about this necessary information about Food safety & Food spoilage, which causes illness to their family.
EXAMINING FACTORS OF CAREER COMMITMENT: CONFIRMATORY FACTOR ANALYSIS
Authors: Kasaraneni Hima Jyothi , Rosaline Salini
Published: February 2023

There is a tremendous revolution in the education sector around the globe during the recent years. Remote work, not a new word in a few countries earlier, is emerged as a new normal way of working in every corner of the world due to the Covid-19 outbreak. The faculty not only need to adapt to the new ways of teaching but also need to be flexible to the working hours. These circumstances pose challenges such as work-life balance and career management, specifically career commitment on every faculty. The motive of this paper is to study four factors consisting of a total of 24 items and to report the results of a study on the factors that lead to the career commitment of faculty. Exploratory factor analysis that was done on the collected data has identified four significant dimensions, namely employee empowerment, adaptive self-efficacy, adaptive behaviour, and career commitment. Confirmatory factor analysis results have also presented a good model fit in the study. The findings of the results provide insights for the faculty working in educational institutions in enhancing their career commitment through empowerment, adaptive self-efficacy, and adaptability.
TRACING THE ADVANCEMENTS IN ARTIFICIAL INTELLIGENCE: DRAWING LESSONS FOR TOMORROW
Authors: Kaur Mandeep , Vikas Sona , A G Rekha
Published: February 2023

Artificial Intelligence (AI) as a technology with its application and tools has transformed almost every aspect of our lives. AI has witnessed extensive growth in the past decade, due to the enhanced power of computing and the wide range of tools and technologies that have been introduced and developed. Though notwithstanding the current stage, Artificial Intelligence has gone through its fair share of inexplicable fluctuations in the past. This research paper aims to help the researchers and practitioners better understand the growth of AI and the obstacles in its advancements as they build focus on the next development of AI and related technologies. The paper's objective is to provide valuable insights into the evolution of Artificial Intelligence as a technology and take lessons for the future. This research has been conducted based on the literature review of relevant books, articles, papers published on this subject. By understanding the evolution of AI through its ebbs and flows, the researchers can anticipate and be prepared for any vicissitude that could be a stumbling block in the truly remarkable growth of this technology which has made a far-reaching and wide-ranging impact.
IDENTIFIKASI SENYAWA KIMIA DAN UJI AKTIVITAS INHIBISI ENZIM ?-AMILASE EKSTRAK ETANOL AKAR TEMBELEKAN (Lantana Camara L.)
Authors: Nurpatria Muhammad Andya , Muhtadi
Published: March 2023

Diabetes melitus merupakan salah satu problematika kesehatan yang prevalensinya semakin bertambah, mempunyai resiko besar terjadi komplikasi, sampai dapat menyebabkan kematian. Peningkatan kadar gula didalam darah salah satu penyebabnya adalah aktivitas pemecahan pati dari enzim alfa-amilase yang merupakan produk dari kelenjar pankreas dan saliva. Tanaman herbal yang dilaporkan memiliki khasiat sebagai antidiabetes adalah akar tembelekan. Fraksi dari akar tembelekan (Lantana camara L.) mempunyai potensi sebagai pengobatan antihyperglikemia. Hasil riset menunjukkan ekstrak etanol tembelekan dapat menurunkan kadar glukosa darah pada hewan uji dengan dosis 200 mg/Kg BB dan 400 mg/Kg BB. Metode spektrofotometri dipilih untuk melakukan pengujian terhadap aktivitas enzim ?-amilase dengan cara mengukur absorbansi sisa substrat yang membentuk kompleks warna biru dengan iodine-iodida. Hasil identifikasi FTIR ekstrak etanol akar tembelekan memiliki spektrum yang mirip dengan senyawa coumaran yaitu dengan adanya gugus alkana pada bilangan gelombang 2939,72 cm-1 dan 2920,54 cm-1. Hasil Ekstrak akar tembelekan mampu menghambat enzim ?-amilase dengan nilai IC50 yaitu 35.345 ppm dengan kontrol positif pembanding acarbose 20.750 ppm. Hasil analisis uji T-test ditemukan hasil yang menunjukkan bahwa terdapat perbedaan yang bermakna antara IC50 acarbose dan IC50 ekstrak etanol akar tembelekan dengan nilai p-value <0,05.
Kata kunci : Lantana camara L., Inhibisi, enzim ?-amilase, Spektrofotometer UV-Vis, In Vitro
ORIENTAÇÃO EMPREENDEDORA CORPORATIVA: UM ESTUDO EM MICRO, PEQUENAS E MÉDIAS EMPRESAS DO ESTADO DO MATO GROSSO DO SUL
Authors: ALCANTARA L. R , SILVA L. C. S.
Published: March 2023

Esta pesquisa foi fruto de um projeto de iniciação científica (IC) realizado pelo Laboratório de Pesquisa em Inovação e Transferência de Tecnologia (LABin) da Universidade Federal da Grande Dourados. E teve como objetivo analisar o cenário das micro, pequenas e médias empresas do Estado do Mato Grosso do Sul, identificando o nível da orientação empreendedora (OE) vivenciada em seus ambientes internos. A metodologia de pesquisa foi uma abordagem qualitativa, e teve como procedimentos técnico, a pesquisa bibliográfica e survey, objetivando realizar a partir do estudo das teorias referente à orientação empreendedora, uma análise do cenário utilizando-se da coleta de dados aplicada a colaboradores de micro, pequenas e médias empresas do Mato Grosso do Sul. Nos resultados obtidos, foi possível identificar que independente do cargo ocupado, os funcionários indicam apresentar as dimensões da OE, tendo rotinas empresariais propícias para a construção de um ambiente de mútuo comprometimento, onde os mesmos se sintam acolhidos e apoiados no processo de inovação, recebendo estímulos para manifestarem comportamento empreendedor e solucionarem problemas internos e externos enfrentados constantemente pelas empresas.
COMUNICAÇÃO CIENTÍFICA E PSEUDOCIÊNCIA: UM DESAFIO EPISTEMOLÓGICO
Authors: Uliana Barboza Eduardo Fernando
Published: March 2023

O artigo propõe uma discussão teórica sobre os desafios epistemológicos da divulgação científica em um momento crítico para as pesquisas acadêmicas brasileiras com reduções constantes de bolsas de pesquisa e verbas para a área. O crescimento vertiginoso da disseminação de informações e notícias falsas, com mais intensidade durante a pandemia de COVID-19, sobre descobertas científicas e os mais variados assuntos impulsionados principalmente por boatos, teorias conspiratórias e afirmações com aparência científica, mas que partem de premissas falsas e sem nenhum critério e rigor científicos. O texto discute também o papel dos meios de comunicação especializados enquanto divulgadores das pesquisas realizadas nas universidades e como melhorar o acesso do público às descobertas científicas, abordando o tema como um desafio multidisciplinar.