bluuebunny/crossref_metadata_2025 huggingface dataset:
Class B β-Lactamases: the Importance of Being Metallic
Authors: Vila Alejandro J. , Cricco Julia A.
Published: January 2023

The structural and functional features of class B β-lactamases, which are metal-dependent, are reviewed in this article. Enzymes from different bacterial strains exhibit a common fold and sequence similarity in their active sites. However, the protein scaffold fine tunes the metal binding affinity and substrate selectivity. In this way, some metallo- β-lactamases seem to be functional with only one Zn(II) equivalent per enzyme, whereas others require a binuclear active site. The sequence
similarity leads to a subdivision of these enzymes into three subclasses. The substrate rather broad, except for enzymes belonging to subclass B2. Some inhibitors have been designed and tested, but none of them is able to exhibit a broad spectrum against these enzymes.
Early Family Intervention for Youth at Risk for Bipolar Disorder: Psychosocial
and Neural Mediators of Outcome
Authors: Miklowitz David J. , Weintraub Marc J. , Walshaw Patricia D. , Schneck Christopher D. , Chang Kiki D. , Merranko John , Garrett Amy S. , Singh Manpreet K.
Published: January 2023

Background:

The impairing neurodevelopmental course of bipolar disorder (BD) suggests the importance of early intervention for youth in the beginning phases of the illness.

Objective:

We report the results of a 3-site randomized trial of family-focused therapy for youth
at high-risk (FFT-HR) for BD, and explore psychosocial and neuroimaging variables as
mediators of treatment effects.

Methods:

High-risk youth (<18 years) with major depressive disorder or other specified BD,
active mood symptoms, and a family history of BD were randomly assigned to 4 months of FFT-
HR (psychoeducation, communication and problem-solving skills training) or 4 months of
enhanced care psychoeducation. Adjunctive pharmacotherapy was provided by study
psychiatrists. Neuroimaging scans were conducted before and after psychosocial treatments in
eligible participants. Independent evaluators interviewed participants every 4-6 months over 1-4
years regarding symptomatic outcomes.

Results:

Among 127 youth (mean 13.2+2.6 years) over a median of 98 weeks, FFT-HR was
associated with longer intervals prior to new mood episodes and lower levels of suicidal ideation
than enhanced care. Reductions in perceived family conflict mediated the effects of
psychosocial interventions on the course of mood symptoms. Among 34 participants with pre-
/post-treatment fMRI scans, youth in FFT-HR had (a) stronger resting state connectivity between
ventrolateral PFC and anterior default mode network, and (b) increased activity of dorsolateral
and medial PFC in emotion processing and problem-solving tasks, compared to youth in
enhanced care.

Conclusion:

FFT-HR may delay new mood episodes in symptomatic youth with familial liability
to BD. Putative treatment mechanisms include neural adaptations suggestive of improved
emotion regulation.
A Comparative Analytical Review on Machine Learning Methods in Drugtarget
Interactions Prediction
Authors: Nikraftar Zahra , Keyvanpour Mohammad Reza
Published: January 2023

Background:

Predicting drug-target interactions (DTIs) is an important topic of study in the field of drug discovery and development. Since DTI prediction in vitro studies is very expensive and time-consuming, computational techniques for predicting drug-target interactions have been introduced successfully to solve these problems and have received extensive attention.

Objective:

In this paper, we provided a summary of databases that are useful in DTI prediction and intend to concentrate on machine learning methods as a chemogenomic approach in drug discovery. Unlike previous surveys, we propose a comparative analytical framework based on the evaluation criteria.

Methods:

In our suggested framework, there are three stages to follow: First, we present a comprehensive categorization of machine learning-based techniques as a chemogenomic approach for drug-target interaction prediction problems; Second, to evaluate the proposed classification, several general criteria are provided; Third, unlike other surveys, according to the evaluation criteria introduced in the previous stage, a comparative analytical evaluation is performed for each approach.

Results:

This systematic research covers the earliest, most recent, and outstanding techniques in the DTI prediction problem and identifies the advantages and weaknesses of each approach separately. Additionally, it can be helpful in the effective selection and improvement of DTI prediction techniques, which is the main superiority of the proposed framework.

Conclusion:

This paper gives a thorough overview to serve as a guide and reference for other researchers by providing an analytical framework which can help to select, compare, and improve DTI prediction methods.
L-Tartaric Acid Exhibits Antihypertensive and Vasorelaxant Effects:
The Possible Role of eNOS/NO/cGMP Pathways
Authors: Amssayef Ayoub , Bouadid Ismail , Eddouks Mohamed
Published: January 2023

Aims:

The aim of the study was to investigate the antihypertensive effect of L-Tartaric
acid.

Background:

L-Tartaric acid (L-TA) is a well-known weak organic acid that naturally occurs in a
wide range of fruits, most notably in grapes, tamarind, and citrus.

Objective:

The present study aimed to assess the effect of acute and subchronic administration of
L-TA on blood pressure parameters in normotensive and hypertensive rats as well as its vasorelaxant
potency.

Methods:

In the current study, the antihypertensive activity of L-TA was pharmacologically studied.
L-NAME-induced hypertensive and normotensive rats received L-TA (80 and 240 mg/kg)
orally over six hours for the acute experiment and seven days for the subchronic treatment. Thereafter,
systolic, diastolic, mean, mid arterial blood pressure, and pulse pressure as well as heart rate
were evaluated. In the in vitro experiment, the vasorelaxant ability of L-TA was performed in ratisolated
thoracic aorta.

Results:

An important drop in blood pressure was recorded in L-NAME-induced hypertensives
treated with L-TA. This molecule also produced a dose-dependent relaxation of the aorta precontracted
with norepinephrine (NEP) and KCl. The study demonstrated that the vasorelaxant capacity
of L-TA seems to be exerted through the activation of eNOS/NO/cGMP pathways.
A Study of Federated Learning with Internet of Things for Data Privacy
and Security using Privacy Preserving Techniques
Authors: Shakeer Shaik Mahamad , Babu Madda Rajasekhara
Published: January 2023

Privacy leakage that occurs when many IoT devices are utilized for training centralized
models, a new distributed learning framework known as federated learning was created, where devices
train models together while keeping their private datasets local. In a federated learning setup, a
central aggregator coordinates the efforts of several clients working together to solve machine learning
issues. The privacy of each device's data is protected by this setup's decentralized training data.
Federated learning reduces traditional centralized machine learning systems' systemic privacy issues
and costs by emphasizing local processing and model transfer. Client information is stored locally
and cannot be copied or shared. By utilizing a centralized server, federated learning enables each
participant's device to collect data locally for training purposes before sending the resulting model
to the server for aggregate and subsequent distribution. As a means of providing a comprehensive
review and encouraging further research into the topic, we introduce the works of federated learning
from five different vantage points: data partitioning, privacy method, machine learning model,
communication architecture, and systems heterogeneity. Then, we organize the issues plaguing federated
learning today and the potential avenues for a prospective study. Finally, we provide a brief
overview of the features of existing federated knowledge and discuss how it is currently being used
in the field.
Utilisation of Plastic Waste as Synthetic Fiber and Aggregate in Concrete –A Review
Authors: Rao Marabathina Maheswara , Patro Sanjaya Kumar , Acharya Prasanna Kumar
Published: January 2023

Plastic waste materials are non-biodegradable and therefore require safe and economic disposal to have a green environment. The use of plastic waste in the construction industry holds a big potential in minimizing the global environmental burden. For this purpose a comprehensive review of published research works was done which disclosed the use of plastic waste materials like polypropylene (PP), high-density polypropylene (HDPE) and polyethylene terephthalate (PET) in concrete as partial or full replacements for cement and aggregates. This paper reviewed various properties like workability, compressive strength, split tensile strength, flexural strength, temperature effect, elastic modulus, drying shrinkage, carbonation and structural behavior of concrete with stated plastic waste materials. The review revealed that the strength, durability and structural characteristics of such concrete improved while the workability was reduced. The review gave information that the footpath panels with HDPE, PP and PET fibre can be used as a substitute for steel-reinforced panels. The review also indicated that further detailed investigations on various strength and durability properties are required on concrete made using plastic wastes like HDPE, PP and PET with various aspect ratios.
Etiological Insights into TNBC and their Related Catastrophic Risks
Authors: H Nair Haritha , John Anto Ruby
Published: January 2023

Triple-negative breast cancer is the most aggressive form of breast cancer
that lacks expression of estrogen, progesterone, and human epidermal growth factor
receptor 2. TNBC is characterized by poor clinic-pathological attributes, prognostic
markers, unavailability of efficient therapeutic approaches, and higher chances of
disease relapse along with metastasis to distant sites. Dysregulated epigenetic and
transcriptional profiling was involved in cancer progression including histone
modification, altered miRNA, DNA methylation, and long non-coding RNA signatures.
This chapter will provide an insight into the molecular biology of TNBC including
gene expression patterns and their subtypes. TNBC molecular spectrum was
extensively studied to depict the distant metastasis-free survival and overall survival
rate in affected individuals. Prevalence and epidemiology trends of TNBC patients
across the globe were also studied to determine the impact of genetic predisposition
and socioeconomic factors behind its aggressive behavior. 
Studi Perencanaan Dinding Penahan Sebagai Upaya Penanganan Kelongsoran Lereng Pada Ruas Jalan Trenggalek - Ponorogo Provinsi Jawa Timur
Authors: Rosdiyono Anangga , Hendrawan Andre Primantyo , Asmaranto Runi
Published: January 2023

Slope failure and landslide are still a seriously problem and occur on various parts in Indonesia. If this slope failure occurs, it can cause property losses and fatalities. This slope failure study is located on Trenggalek â€“ Ponorogo road (Km 16+650 â€“ Km 16+750) and (Km 17+400 â€“ Km 17+550) East Java Province which has steep topography condition.. From the results of the original slope analysis using the Geo5 software, it found that the safety factor values for slope stability was â‰¤ 1,5 without earthquake effect. As for the stability of the slope with the influence of the earthquake, the results of the safety factor for the original slopes of â‰¤ 1,1. Based on the analysis of the safety factor, the existing condition that the original slope is not safe therefor necessary to improve the slope repair using retaining wall as an effort to handle slope failure .From the results analysis slope stability of the slope again after repairing the slope with retaining wall, it show better safety without earthquake effect with value â‰¥ 1,5 and safe value of â‰¥ 1,1 due to earthquake load. Meanwhile to resolve the problem solve of slope failure using retaining wall requires a budget of Rp. 11.934.155.000.Kegagalan lereng dan tanah longsor masih menjadi masalah serius dan sering terjadi di berbagai wilayah Indonesia. Bila terjadi kegagalan lereng ini maka dapat menyebabkan kerugian baik secara materil dan imateril. Studi kegagalan lereng ini berada di ruas jalan Trenggalek â€“ Ponorogo (Km 16+650 â€“ Km 17+750) dan (Km 17+400 â€“ Km 17+550) Provinsi Jawa Timur dimana memiliki kondisi topografi curam. Dari berbagai macam faktor penyebab kegagalan lereng dan tanah longsor maka perlu mengetahui faktor aman lereng pada ruas jalan Trenggalek â€“ Ponorogo. Dari hasil analisis stabilitas lereng asli menggunakan bantuan software Geo5 didapatkan hasil bahwa nilai faktor aman terhadap stabilitas lerengÂ  â‰¤ 1,5 tanpa adanya pengaruh gempa. Sedangkan untuk stabilitas lereng dengan pengaruh gempa didapatkan hasil faktor aman terhadap lereng alami â‰¤ 1,1. Berdasarkan analisis nilai faktor aman kondisi eksisting yang menyatakan bahwa lereng asli tidak aman oleh sebab itu, perlu adanya perbaikan lereng menggunakan dinding penahan sebagai upaya penanganan kelongsoran lereng. Dari hasil analisis stabilitas lereng kembali setelah adanya perbaikan lereng dengan dinding penahan menunjukan nilai angka aman yang lebih baik dengan kondisi tanpa gampa dengan nilai â‰¥ 1,5 dan nilai angka aman â‰¥ 1,1 akibat beban gempa. Sedangkan untuk mengatasi masalah kegagalan lereng menggunakan dinding penahan membutuhkan anggaran biaya sebesar Rp. 11.934.155.000,00.
ABNORMAL FREE GAS COLLECTION IN RADIOGRAPHY: A PICTORIAL REVIEW
Authors: Tjakraatmadja Ricardo , Erawati Dini Rachma
Published: January 2023

An abnormal free gas collection in the thorax and abdomen is a condition which is present of abnormal air in the thorax and abdominal cavity that normally not found. Radiological examination plays very important role to detect the presence of abnormal gas, the volume, the location, and the complication. Some of these conditions can represent classic radiological appearance that we can find in everyday practice.
BILATERAL PNEUMOTHORAX IN LUNG METASTASES OF BREAST CARCINOMA: A CASE REPORT
Authors: Kusdjianto Amanda Yuanita , Samsuri  , Andri  , Andi Wijayanto , Agus Subiyantoro , Adi Habibie
Published: January 2023

Introduction: Bilateral pneumothorax is a rare case which happens in 1.3 to 1.9 percent of all cases ofÂ  pneumothorax.1 In breast carcinoma patients, it is due to lung metastasis and first selected conservative therapy.2 Lung metastasis can be found in the appearance of pulmonary nodules called cannon-ball metastases in chest X-Ray (CXR).3 Method: Case report based on findings in chest X-Ray. Result: A 42 year-old female came to ER with sudden shortness of breath and pleuritic pain. She was diagnosed with breast carcinoma 3 years prior the ER visit and had undergone mastectomy on breasts and chemotherapy. Physical examination showed bilaterally decreased breath sounds. CXR AP postion showed bilateral pneumothorax and multiple nodules varied in size indicated lung metastases. Chest tubes with water-sealed drainage were inserted in both side of the lungs. CXR after the insertion showed reduction of the volume of pneumothorax in both side of the lungs and cannon-ball metastases in both sides of the lungs. CXR was performed serially until hospital discharge. Discussion: Bilateral pneumothorax which develops in patients who have history of breast carcinoma is considered very rare.It is caused by the metastatic process and treatment.2 CXR can be used to detect the metastasis and its complications such as pneumothorax.4 Conclusion: Bilateral pneumothorax is rarely seen in patients with breast carcinoma. Early detection of lung metastasis and appropriate therapy of tumor can prevent complications such as pneumothorax.Keywords: bilateral pneumothorax; lung metastases; breast carcinoma; chest X-Ray
Studi Manajemen Konstruksi Proyek Pembangunan Infrastruktur Pengendali Banjir Sungai Welang di Kota Pasuruan
Authors: Candra Yoggi Fracasnofa Komala , Juwono Pitojo Tri , Cahya Evi Nur
Published: January 2023

Dalam proyek pasti memiliki batasan waktu dan biaya yang telah ditentukan, oleh karena itu dibutuhkan manajemen konstruksi untuk mengatasi masalah yang terjadi. Penulisan studi ini bertujuan untuk menganalisa percepatan proyek pembangunan infrastruktur pengendali banjir Sungai Welang di Kota Pasuruan dengan menggunakan program. Alternatif utama yang dilakukan untuk mengatasi masalah pada studi ini adalah dengan menambah durasi jam kerja dan penambahan alat berat. Dalam mengolah alternatif, dibantu menggunakan 3 metode yaitu Gannt Chart, CPM (Critical Path Method), dan PERT (Program Evaluation Review Technique). Metode tersebut dapat mempermudah analisa alternative dan data pekerjaan dalam program. Data analisa dari kontraktor pelaksana yaitu data perencanaan, data harga satuan, dan data kontrak. Analisa alternatif mengeluarkan kurva S dengan bantuan program untuk mempermudah perbandingan antara penambahan durasi jam kerja dan jumlah alat berat. Dari hasil analisa didapatkan, durasi normal proyek selama 165 hari. Hasil optimal dari alternatif penjadwalan adalah penambahan durasi jam kerja dengan penurunan rencana anggaran biaya sebesar 5,84% dan mengalami percepatan durasi pekerjaan sebesar 29,82%.
Validasi Data Curah Hujan Satelit dengan Data Stasiun Hujan di DAS Ngasinan Hulu, Kabupaten Trenggalek, Jawa Timur
Authors: Marta Silvia Dwi , Suhartanto Ery , Fidari Jadfan Sidqi
Published: January 2023

Data curah hujan merupakan salah satu data yang sangat penting dalam analisis hidrologi, baik perencanaan sumberdaya air atupun perencanaan bangunan air. Namun dalam kenyataan di lapangan sering terjadi ketersediaan data yang kurang lengkap, hal tersebut disebabkan oleh beberapa faktor baik dari lingkungan ataupun dari pencatatan data. Dengan berkembangnya teknologi, salah satunya adalah satelit hujan yang mana dapat dijadikan alternatif untuk mencatat curah hujan dengan cakupan yang luas. Adapun satelit yang dapat dijadikan alternatif pada studi ini adalah TRMM 3B42RT dan GPM V6 dimana kedua satelit ini merupakan Kerjasama JAXA dan NASA, keduanya mempunyai spesifikasi yang berbeda dari cakupan wilayahnya saja TRMM 3B42RT sebesar 0,250 x 0,250Â sedangkan GPM V6 0,100 X 0,100. Dalam studi ini guna untuk akurasi estimasi curah hujan TRMM 4B42 dan GPM V6 pada 4 Stasiun Hujan di DAS Ngasinan Hulu. Namun data satelit tidak dapat langsung digunakan melainkan harus dilakukan validasi terhadap data pengukuran untuk meminimalisir error pada data satelit dan data satelit dapat menggantikan data obeservasi yang dibutuhkan. Untuk mengatahui seberapa performa dari masing-masing satelit dilakukan terlebih dahulu proses kalibrasi dan validasi data. Kalibrasi pada studi ini menggunakan regresi linier berganda dengan pemilihan kombinasi variabel, yang mana persamaan yang di dapat digunakan untuk mengoreksi pada tahapan validasi. Adapun parameter statistik yang digunakan untuk menentukan tingkat akurasi dari satelit pada proses validasi yaitu menggunakan nilai RMSE, NSE, dan R (Koefisien Korelasi). Dalam penelitian kedua satelit TRMM 3B42 dan GPM V6 dapat digunakan pada titik lokasi tersebut dilakukan dengan menggunakan periode bulanan yang menghasilkan nilai validasi yang berbeda-beda pada satelit GPM V6 pada nilai RSR, NSE ,dan R berturut-turut sebesar 0,359 ; 0,917 ; 0,964. Untuk hasi validasi terbaik pada satelit TRMM 3B42 dengan nilai RSR, NSE, dan R berturut-turut sebesar 0,245 ; 0,946 ; 0,987. Kedua satelit dapat digunakan pada lokasi studi diakarenakan mengahsilkan nilai parameter yang baik. Pada penelitian ini data curah hujan TRMM 3B42 memiliki tingkat keakurasian yang lebih tinggi berdasarkan hasil validasi, yaitu menghasilkan sebesar 61,1% sesuai dengan data lapangan.
Evaluasi Kapasitas Emergency Gate Floodway Pelangwot-Sedayu Lawas sebagai Sistem Pengendalian Banjir di Bengawan Solo Hilir
Authors: Amalia Dewi , Sumiadi Sumiadi , Dermawan Very
Published: January 2023

Floodway Pelangwot-Sedayu Lawas merupakan infrastruktur utama dalam sistem pengendalian banjir Bengawan Solo Hilir. Berdasarkan kondisi di lapangan, diketahui bahwa masih sering terjadi banjir di daerah Bengawan Solo Hilir, maka dari itu direncanakan untuk meningkatkan kapasitas debit yang akan dialirkan menuju ke floodway, yaitu sebesar 1000 m3/dt. Tujuan studi ini adalah untuk mengetahui kemampuan tiga emergency gate floodway dalam mengalirkan debit banjir 1000 m3/dt dan kemampuan saluran floodway untuk menampung debit dari emergency gate maupun dari Rawa Jabung sebesar 1310 m3/dt. Analisis kemampuan emergency gate untuk mengalirkan debit banjir dilakukan dengan menghitung kapasitas debit yang dapat dialirkan melewati tiga pintu floodway, sedangkan analisis kemampuan saluran floodway dalam menampung debit banjir disimulasikan menggunakan aplikasi HEC-RAS 5.0.7. Hasil analisis menunjukkan dengan bukaan pintu (w) 5 m, ketiga pintu floodway tersebut mampu mengalirkan debit banjir rencana 1000 m3/dt, dengan elevasi di Pelangwot adalah +7,190 mdpl, dengan Â kondisi aliran yang terjadi di hulu pintu adalah aliran bebas. Persentase reduksi banjir Bengawan Solo dengan kapasita floodway 1000 m3/dt, mencapai 30,265%. Saluran floodway eksisting belum mampu mengalirkan debit 1310 m3/dt, sehingga diperlukan peninggian tanggul ataupun normalisasi pada saluran floodway tersebut.
Pemetaan Sebaran Indeks Bahaya Erosi dan Arahan Penggunaan Lahan di Sub DAS Brantas Hulu Kota Batu Berbasis Sistem Informasi Geografis
Authors: Rosidin Deny Ainur , Suhartanto Ery , Andawayanti Ussy
Published: January 2023

SubDAS Brantas Hulu termasuk dalam salah satu area DAS yang mengalami perubahan terhadap berkurangnya kemampuan DAS dari segi menyimpan air dan semakin besarnya laju erosi maupun sedimentasi. Terkait dengan penanganan yang akan dilakukan, perlu dilakukan adanya analisis terhadap besaran laju erosi dan sedimentasi. Studi ini bertujuan untuk mengetahui nilai indeks bahaya erosi (IBE) oleh Hammer (1981) yang merupakan salah satu parameter untuk mengukur kepekaan tanah dan lahan terhadap kemungkinan erosi yang akan terjadi. Metode MUSLE dipilih sebagai metode utama dalam penentuan laju sedimentasi dengan kombinasi Sedimen Delivery Ratio (SDR) sebagai sarana untuk mendapatkan nilai erosi ditinjau dari hasil analisis sedimentasi.Â Hasil analisis menunjukkan rerata sedimentasi eksisiting adalah 22.97 mm/tahun. Sedangkan hasil IBE Eksisiting diperoleh indeks kriteria sedang (1.0 â€“ 4.0) seluas 350.660 ha (2.19%), indeks kriteria tinggi (4.01 â€“ 10.00) seluas 589.059 ha (3.68%) dan indeks kriteria sangat tinggi (>10.01) seluas 15053.150 ha (94.12%). Hasil dari skenario baru yang mengusung arahan penggunaan lahan berdasarkan ketentuan RLKT dan perubahan pengelolaan lahan (Faktor P) menunjukkan penurunan sedimentasi sebesar 88.30% menjadi 2.69 mm/tahun. Hasil IBE skenario baru diperoleh indeks rendah sampai tinggi (0.01 â€“ 10.00) seluas 14820.89 ha (92.67%) dan indeks sangat tinggi (>10) seluas 1171.97 ha (7.33%). Selain itu diusulkan checkdam pada lahan skenario baru dengan IBE sangat tinggi dengan efektifitas reduksi sedimentasi sebesar 13.46%.
Studi Optimasi Pemanfaatan Air Irigasi Menggunakan Program Linier pada Daerah Irigasi Pirang Kabupaten Bojonegoro
Authors: Triwidianto Heru , Limantara Lily Montarcih , Soetopo Widandi
Published: January 2023

Daerah Irigasi Pirang memiliki luas baku sawah 1.314 Ha yang berlokasi di Kabupatern Bojonegoro. Permasalahan yang terjadi pada daerah irigasi ini yaitu penyimpangan pelaksanaan PTT yang tidak sesuai rencana serta ketersediaan air yang tidak dapat mencukupi kebutuhan irigasi. Maka dari itu diperlukanlah pengoptimalan luas lahan dan debit yang tersedia sehingga dapat memaksimalkan keuntungan pertanian. Optimasi dilakukan menggunakan metode program linier dengan alat bantu fasilitas solver pada Microsoft Excel. Pada studi ini direncanakan 1 PTT eksisting dan 4 PTT alternatif dengan kondisi debit andalan 80% dan 50%. Hasil neraca air pada setiap PTT sebelum dioptimasi mengalami defisit neraca air dengan persentase 22-25%. Namun, setelah dioptimasi seluruh PTT tidak ada yang mengalami defisit neraca air. Dari hasil optimasi juga menunjukkan pada setiap PTT alternatif mengalami peningkatan intensitas tanam dan juga keuntungan hasil pertanian daripada PTT eksisting di kondisi debit andalan 80% maupun 50%. Untuk PTT terbaik pada kondisi debit andalan 80% yaitu alternatif 3 (padi - palawija (kacang tanah) - padi) dengan intensitas tanam 228,33% dan keuntungan Rp. 54.664.759.359, serta pada kondisi debit andalan 50% terpilih alternatif 1 (padi, palawija (jagung) - padi, palawija (jagung) - padi, palawija (jagung)) dengan intensitas tanam 253,37% dan keuntungan Rp. 54.099.646.076.
Analisis Banjir Sungai Sesayap Malinau Kota Menggunakan Aplikasi Zhong Xing HY21
Authors: Fayiz Naufal Muhammad , Juwono Pitojo Tri , Asmaranto Runi
Published: January 2023

Hujan dengan intensitas yang tinggi, yang menyebabkan terjadinya luapan di sungai Sesayap merupakan salah satu penyebab terjadinya banjir. Terjadinya luapan di Sungai Sesayap disebabkan banyak faktor juga, salah satunya kegagalan penampang yang ada yang tidak bisa menampung air yang ada dikarenakan tampungan penampang terkurangi lalu banjir, dan juga berdasarkan rencana RTRW Malinau Kota, kawasan tersebut akan dikembangkan menjadi daerah pusat perkantoran dan pengembangan daerah pemukiman terpadu di Malinau Kota. Maka dari itu diperlukan analisis banjir Sungai Sesayap di Malinau Kota menggunakan Zhong Xing HY21. Analisis tersebut membutuhkan hidrologi pengalisisan untuk memperoleh debit banjir rencana. Penggunaan metodenya dengan Hidrologi Satuan Sintesis Nakayasu dengan Q50 th. Setelah mendapatakan debit banjir rancangan, maka dilakukan analisis rambatan banjir menggunakan Zzhong Xing HY21. Berdasarkan hasil analisis didapatkan seluruh desa tergenang banjir dengan total luasan banjir 51,93 km2. Maka dibuat Rencana Tindak Darurat dengan prioritas evkausai desa Malinau Hulu, Pelita Kanaan, Malinau Kota, Batu Lidung, Tanjung Keranjang, dan Malinau Hilir.
Studi Penjadwalan Pelaksanaan Konstruksi Conduit Pengelak dan Cofferdam pada Bendungan Cijurey Kabupaten Bogor Provinsi Jawa Barat
Authors: Pratama Ivan Kurnia , Marsudi Suwanto , Cahya Evi Nur
Published: January 2023

Pelaksanaan konstruksi conduit pengelak dan cofferdam merupakan pekerjaan rekayasa dengan ukuran yang cukup besar dan melibatkan banyak sumber daya dengan berbagai aktivitas kegiatan. Oleh karena itu, metode dan sistem manajemen yang efisien dan fleksibel diperlukan untuk menjamin pekerjaan dapat diselesaikan tepat waktu dan tepat biaya. Tujuan pada penelitian ini adalah melakukan penjadwalan pelaksanaan konstruksi conduit pengelak dan cofferdam yang merupakan bagian dari Bendungan Cijurey. Analisis permasalahan dilakukan dengan mengevaluasi jadwal pekerjaan, memberikan alternatif pemecahan masalah guna percepatan proyek dengan optimalisasi pekerjaan pada penambahan alat berat dan jam kerja. Dengan durasi awal pelaksanaan konstruksi selama 95 hari kerja, waktu pelaksanaan dapat dipersingkat dengan efisiensi sebesar 20% dengan penambahan jumlah alat berat dan sebesar 22.1% dengan penambahan jam kerja tambahan. Hal ini juga berdampak pada biaya pelaksanaan proyek yang terjadi efisien sebesar 2.21%Â dan 2.89% akibat penambahan jumlah alat berat dan penambahan jam kerja tambahan pada pelaksanaan konstruksi ini. Dapat disimpulkan bahwa penambahan durasi jam kerja membutuhkan anggaran yang lebih kecil dibandingkan dengan opsi penambahan alat berat, dan dipilih sebagai alternatif pilihan terbaik dalam efisiensi pekerjaan conduit pengelak dan cofferdam Bendungan Cijurey.
Penilaian Indeks Kinerja Sistem Irigasi Daerah Irigasi Grogol Kabupaten Kediri Dengan Menggunakan Aplikasi Epaksi
Authors: Khabib Muhammad Lukman , Siswoyo Hari , Prayogo Tri Budi
Published: January 2023

Daerah Irigasi Grogol memiliki luas fungsional sebesar 365 Ha, sebagian daerah tersebut terkena dampak pembangunan Bandara Dhoho Kediri yang menyebabkan sebagian aset tidak berfungsi. Oleh karena itu penelusuran lapangan diperlukan untuk mengetahui kondisi aset dan menilai kinerja jaringan irigasi pada daerah irigasi Grogol. Setelah dilakukan penelusuran didapat 10 bangunan irigasi dan 3 saluran irigasi hilang dari keseluran bangunan yang berjumlah 45 bangunan dan 23 saluran. Indeks Kinerja Jaringan Irigasi (IKSI) yang didapat dengan aplikasi Epaksi sebesar 69,25% dan metode manual PU sebesar 67,24%. Biaya yang diperlukan untuk perbaikan aset yang rusak sebesar Rp. 46.856.762 yang mencakup 2 saluran rusak dan 2 bangunan pengukur debit yang mengalami kerusakan. Untuk Angka Kebutuhan Nyata Operasi dan Pemeliharaan yang dibutuhkan sebesar Rp. 607.954.573.
Studi Penilaian Kinerja dan Angka Kebutuhan Nyata Operasi dan Pemeliharaan (AKNOP) Sungai Bajak di Kota Semarang
Authors: Nugroho Faishal Dary , Sholichin Moh , Prayogo Tri Budi
Published: January 2023

Menurunnya fungsi sungai dan prasarana sungai berdampak pada berkurangnya fungsi pemenuhan air dan pengendalian daya rusak air. Kegiatan pemeliharaan diperlukan dalam mempertahankan sungai dan prasarana sungai. Studi ini bertujuan untuk memperoleh hasil nilai kinerja dan AKNOP sungai dan prasarana sungai di lokasi penelitian dengan identifikasi dan analisis tingkat kerusakan serta perhitungan biaya AKNOP sesuai dengan yang tertuang dalam Pedoman SE Dirjen SDA No. 5/2016. Hasil studi menunjukkan bahwa penilaian kinerja Sungai Bajak di Kota Semarang rata-ratanya adalah 55,02% dengan rekomendasi pemeliharaan korektif. Satu ruas sungai bagian kanan dan kiri yang mendapatkan rekomendasi pemeliharaan rehabilitatif yaitu pada ruas km1+800 - km1+900, serta 4 ruas sungai bagian kiri dengan pemeliharaan preventif pada ruas km0+000 - km0+400, dan sisanya dengan rekomendasi pemeliharaan korektif. Penanganan dipriotitaskan terhadap ruas yang mendapatkan rekomendasi pemeliharaan rehabilitatif, lalu preventif, serta korektif.Â Total Nilai AKNOP (Angka Kebutuhan Nyata Operasi dan Pemeliharaan) untuk Sungai Bajak di Kota Semarang adalah sebesar Rp. 2.716.600.000,00.
Studi Evaluasi dan Pengembangan Jaringan Distribusi Air Bersih di Kecamatan Brondong Kabupaten Lamongan
Authors: Rahadjeng Aira Azzahra , Haribowo Riyanto , Sholichin Moh
Published: January 2023

Kecamatan Brondong Kabupaten Lamongan memiliki sepuluh desa dengan satu desa telah dilayani oleh Perum Jasa Tirta 1 untuk kebutuhan air bersihnya yaitu Desa Sedayulawas. Dalam rencana pembangunan hingga tahun 2040 terdapat penambahan daerah pelayanan untuk 2 desa lainnya, yaitu Desa Sendangharjo dan Desa Brengkok. Pada penelitian ini dilakukan evaluasi terhadap kondisi eksisting dengan memperhatikan kuantitas dan kontinuitas air pada jaringan eksisting. Hal ini digunakan sebagai acuan untuk melaksanakan perencanaan pembangunan pada tahun 2040 di masa yang akan datang. Perencanaan jaringan air bersih menggunakan apliaksi WaterCAD V8i dimana gunanya untuk mensimulasikan juga memodelkan keadaan hidrolika jaringan air bersih. Menghitung biaya dan analisis ekonomi dilakukan secara manual, mengacu pada SNI 06-4829-2005, hasil analisis hidrolika telah sesuai dengan kriteria standar yang ada, dengan velocity berkisar antara 0,10 â€“ 1,60 m/s gradien headloss mulai dari 0,00 â€“ 14,79 m/km, nilai pressure berkisar antaraÂ 0,50 â€“ 7,79 atm. Rencana anggaran biaya yang diperoleh sebesar Rp. 14.933.759.000 dan harga airnya Rp. 4.594,21/m3.
PERENCANAAN DISTRIBUSI AIR BERSIH DI KECAMATAN HULU PALIK KABUPATEN BENGKULU UTARA DENGAN SOFTWARE WATERCAD 8i
Authors: Rama Alri Ananda Waskita , Sholichin Moh , Fidari Jadfan Sidqi
Published: January 2023

Kecamatan Hulu Palik merupakan bagian dari Kabupaten Bengkulu Utara, daerah tersebut memiliki ketersediaan air bersih yang besar dan kontinu sepanjang tahun pada mata air Batu Layang. Namun, pendistribusian air bersih masih kurang baik. Sehingga, diperlukan suatu upaya untuk mengoptimalkan pemanfaatan ketersediaan air dengan merencanakan sistem jaringan distribusi air bersih yang nantinya dapat dirasakan manfaatnya bagi masyarakat Kecamatan Hulu Palik. Studi ini melakukan perencanaan jaringan baru dengan usia guna hingga tahun 2041, sehingga perlu dilakukan proyeksi jumlah penduduk dan mengetahui debit kebutuhan air hingga tahun 2041. Analisa terhadap aspek hidrolika pada jaringan perpipaan, kualitas air terhadap sisa klorin dan perhitungan RAB pipa yang mengacu pada Harga Satuan Pekerjaan Kabupaten Bengkulu Utara menggunakan Software WaterCAD V8i. Berdasarkan RAB, dapat menghitung Analisa Ekonomi hingga penentuan harga air. Pada tahun 2041 jumlah penduduk daerah layanan sebanyak 14341 jiwa dengan kebutuhan air harian rerata sebesar 22.90 lt/dt. Indeks kelayakan perencanaan meliputi tekanan, kecepatan, kemiringan hidrolis sisa klorin dan kelayakan ekonomi. Berdasarkan hasil analisa terhadap indeks kelayakan, perencanaan jaringan distribusi air bersih Kecamatan Hulu Palik dinyatakan layak. Rencana anggaran biaya yang diperlukan sebesar Rp 11,692,745,64. Analisa Ekonomi dilakukan dengan menggunakan suku bunga sebesar 3.5% dan usia guna hingga tahun 2041, didapat harga air sebesar Rp 3,947.38/m3.
Transformation of commemorative practices in Ukrainian historical discourse
Authors: Dodonov Roman
Published: January 2023

The article is devoted to the study of changes taking place in Ukrainian society in the field of content of historical memory and forms of commemorative practices. The purpose of the study is to identify the main trends in transformations of the form and content of commemorative practices in the Ukrainian historical discourse. During the semi-structured, focused interview with 51 experts representing the main regions of Ukraine, it has been found that current commemorative practices are based on a symbiosis of monologue and dialogue models of memory. The remnants of the Soviet-style totalitarian worldview have led to the popularity of the model of memory, in which the state’s monopoly on history prevails. The idea that national memory consists of many particular commemorations is difficult for Ukrainian society to accept. The past is a kind of symbolic resource, the use of which contributes to the legitimization of Ukraine as an independent state. However, the forms of commemoration remain largely old. Along with fundamentally new forms, primarily related to Internet technologies and social networks, in Ukraine, just as in the Soviet period, commemoration is focused on honoring heroes and victims. At the same time, there is a radical reassessment: the heroes of the Soviet era have become villains, and villains have become heroes. All this points to the “hybrid nature” of commemorative practices with an emphasis on the martyrological-victim component and the trauma of the social psyche of Ukrainians.
Methods of shaping the historical memory among higher education students
Authors: Romantsov Volodymyr , Romantsova Natalya
Published: January 2023

The article discusses the problem of developing the historical memory of students based on the accurate history of Ukraine in the context of forming civic consciousness among future specialists. Solving this problem is essential in the context of full-scale Russian military aggression, where deceitful enemy propaganda tries to justify fictional, pseudo-scientific historical myths. This topic is covered in the context of an interdisciplinary approach, anthropological history, and history of mentality.The theoretical positions of Ukrainian and foreign scientists support the publication of the chosen topic (Gyrych, V. Hrynevych, L. Zashkilnyak, I. Kovalska-Pavelko, H. Kasyanov, V. Masnenko, L. Nagorna, P. Nora, E. D. Smith, Y. Shapoval, B. Shatska, O. Shevel, and others). The study proves the need to transform historical memory in the context of the historical policy and memorial legislation of events. On the principles of these methodological approaches, the issues of the historical policy of the modern Ukrainian state during the Russian-Ukrainian war that address the ideas of communist totalitarian influence in the students' minds are considered. According to the interdisciplinary approach, the article combines elements of history and sociology.
Monumental art as a means of constructing historical memory in Soviet Ukraine
Authors: Petrova Inna , Khromova Olga
Published: January 2023

The article is devoted to the study of the construction of historical memory in the Ukrainian SSR by means of monumental art. The relevance of this problem in the context of Russia's hybrid war against Ukraine is emphasized, in which the existence of the Soviet model of historical memory in society has long been the subject of manipulation and serves the purpose of justifying aggression against our state. Since the narratives of historical memory require external manifestation in works of art and the creation of appropriate places of memory, the latter often become important components of state propaganda for the creation of a single concept of collective memory. Therefore, the main task of the study was to show the role of monumental art in the context of memory politics in Ukraine during the Soviet era and the mechanisms of its transformation into a means of Soviet propaganda. In the research process, the methods of content analysis of archival documents and art analysis of monuments of Ukrainian monumental art of the second half of the 20th century were used. As a result, it is proven that in Soviet Ukraine, monumental art turned into an important element of state propaganda, which aimed to create such a concept of collective memory, which would be included in the general structure of communist ideology and justify the existing socio-political system. Most of the works of monumental art were aimed at building a certain cult, primarily the cult of work and the cult of achievements of the Soviet government, the cult of the "primacy" of Soviet people in certain spheres. Around the greatness of past victories, which were the foundation of the image of historical memory, it was easier to unite a large number of people and form a new Soviet identity. Directing the creative energy of Ukrainian artists to the service of Soviet ideology became possible thanks to the establishment of totalitarian control over Ukrainian artists by state institutions, which often completely destroyed the original authorial concept of the works, but turned them into an effective means of forming a distorted construct of a collective perception of the past.
Caricature as one of the information mechanisms for constructing the image of Russia's war against Ukraine: according to the materials of "The Times" and "The Sunday Times"
Authors: Kutsyk Ruslan
Published: January 2023

The article presents the author's vision of the caricature as an informational mechanism for constructing the image of Russia's war against Ukraine. The subject of the study was the satirical graphics of one of the most famous and authoritative publications in the world - the British newspaper "The Times" and its separate Sunday edition "The Sunday Times". Chronologically, the work covers a small but revealing period: the first 7 days of Russia's full-scale armed aggression. At this time, the world mass media literally "exploded" with news reports about events in Ukraine.As a result of the research, it was established that from the first days of the full-scale war, the cartoonists of "The Times" and "The Sunday Times" took a clearly expressed pro-Ukrainian and anti-Russian position. The main object of their ridicule was V. Putin, who was attached to a series of different images: "Russian-Soviet leader", "half-naked macho" and "dwarf". With the increase in the number of rocket attacks on Ukrainian cities and killed civilians, the authors of the cartoons treated the image of the Russian president even more contemptuously, emphasizing the fact of his degradation as a type of "reasonable person". The positive image of the Ukrainian president became a direct counterpoint to the negative image of V. Putin. To the readers of The Times and The Sunday Times, V. Zelensky appears as a "great leader" who, personifying Ukraine and its people, courageously resists the onslaught of the Russian army. Cartoonists also drew attention to the image of political leaders of the West, who are also criticized for their inability to successfully oppose Russia's armed aggression. The policy of the British government regarding the settlement of the entry of Ukrainian refugees to the United Kingdom was separately ridiculed.
Why should Ukraine be a fast state for overcoming war consequences?
Authors: Zharova Liubov
Published: January 2023

A full-scale invasion of Ukraine became a challenge not only for it, but also for the whole world, which has not yet overcome the consequences of the covid pandemic. Rethinking approaches to assessing the impact of military actions on the economy requires the development of new theoretical foundations and practical recommendations. Previous experience cannot be used, including as a result of changes due to globalization processes.The modern world is characterized by openness and interdependence at all levels - from economic to social. That is why blocking ports in Ukraine can cause famine in African countries. The influence of civil society affects the economic behavior of international corporations, which are forced to leave the market of the Russian Federation not only because of sanctions, but also to preserve the image and loyalty of consumers. The creation of a single European space currently also requires the formation of a single line of behavior in relation to Ukraine and Russia. This is far from a complete list of the latest relationships that shape the modern world and affect the economy.Currently, Ukraine suffers losses every day, the amount of which cannot be fully estimated. This is hindered by the incompleteness of information, the continuation of hostilities, and the inconsistency of existing methods with the current situation.In the article, based on the analysis of the existing situation and existing challenges, the concept of a fast state is proposed. The idea grounds the socio-economic state's development on the maximum promotion of entrepreneurial activity. It is based on a synergistic effect when the introduction of business opportunities will stimulate the creation of new workplaces, the growth of incomes, and with them, the expenses of the population, which in turn will boost the opening of new enterprises and the development of existing ones. The central, new idea of a fast state is to concentrate not on raising taxes but on reducing them as much as possible and filling the budget due to the growth of entrepreneurial activity, and not on increasing levies on those that are still functioning. Also, the research makes the point that the reconstruction of the state in the context of a fast state will be built based on finding one's own innovative trajectory of development and not on the adaptation of best practices focused on the catch-up nature of such action.
Who discovered the Donetsk coal basin and when it was discovered
Authors: Haiko Hennadii , Biletsky Volodymyr , Biletskyi Vitaly
Published: January 2023

In the article, the authors raise the topical issue of historical falsifications, considering them as an element of information warfare. Applying the historiographical method and interpreting the facts of the creation of historical misinformation as manipulation of public consciousness, they present a specific case of historical research on the discovery of the Donetsk coal basin. Therefore, a review of the scientific and encyclopedic literature of Russia, the USSR and Ukraine devoted to the coverage of this issue was made; archival historical documents that show the real picture of the discovery of coal in Donbas have been put into scientific circulation; the manipulative discourse of influence on the mass consciousness is tracked in order to create a mythological narrative about the “Russianness” of Donbass. It has been proven that the falsifications of Russia and the USSR regarding the history of the first discovery of coal in the Donbass have been going on for almost the entire period of the industrial development of the region and to this day, it is an example of an information war against Ukraine. The archival historical documents released by the authors unequivocally indicate that the official discoverers of coal deposits in Donbas were other historical figures than those described in Russian and Soviet scientific and encyclopedic literature, and they are of Ukrainian origin. The methods of spreading the mythological narrative and their actualization during the Russian-Ukrainian war are defined, which are typical for the manipulation of mass consciousness.
Ending Electoral Fraud in Nigeria: can the Agenda Setting Role of the Mass Media salvage the situation?
Authors: Nwamara Chinedu A. , Etumnu Emeka Williams
Published: January 2023

In Nigeria, electoral fraud has arguably become prevalent. As a result of it, most electorate seems to have lost faith in the electoral process. In all this, the media have a great role to play in correcting this anomaly that has been denting the Nigerian democratic image through their agenda setting function. This study was underpinned on agenda setting theory. The survey research method was adopted. The population comprises 180 registered and practicing journalists in Imo State. The census principle was used in the study. The approach of purposive sampling was adopted. The data gathering instrument was a questionnaire and analysis was done using descriptive statistics and mean analysis. Finding revealed that the media through their agenda setting function can salvage the issue of electoral fraud in Nigeria. It was recommended that having known the mass media have great tendency to influence change, creators of mass media contents in the Nigerian media industry should not relent in their efforts in packaging mass media content that can help in raising the consciousness of the people towards the danger of electoral fraud with the intention of ending it.
Computer-Aided Diagnosis for the Early Breast Cancer Detection
Authors: Aziz Miran Hakim , Alan Anwer Abdulla
Published: January 2023

Computer-aided diagnosis (CAD) system is a prominent tool for the detection of different forms of diseases, especially cancers, based on medical imaging. Digital image processing is a critical in the processing and analysis of medical images for the disease diagnosis and detection. This study introduces a CAD system for detecting breast cancer. Once the breast region is segmented from the mammograms image, certain texture and statistical features are extracted. GLRLM feature extraction technique is implemented to extracted texture features. On the other hand, statistical features such as skewness, mean, entropy, and standard deviation are extracted. Consequently, on the basis of the extracted features, SVM and kNN classifier techniques are utilized to classify the segmented region as normal or abnormal. The performance of the proposed approach has been investigated via extensive experiments conducted on the well-known MIAS dataset of mammography images. The experimental findings show that the suggested approach outperforms other existing approaches, with an accuracy rate of 99.7%.