bluuebunny/crossref_metadata_2025 huggingface dataset:
Pawai Miniatur Truk sebagai Arena Hiburan Baru Masyarakat Rural: Sebuah Praktik Sosial
Authors: Fredianto Dadang , Septiawan Fariz Eko
Published: April 2021

Pawai miniatur truk telah menjadi hiburan baru bagi masyarakat pedesaan di Jawa Timur bagian Selatan. Para peserta membuat miniatur truk lengkap dengan aksesoris dan desain interior yang dibuat semirip mungkin dengan aslinya. Para pecinta miniatur truk menampilkan karya mereka di acara karnaval untuk memperebutkan hadiah dan pengakuan dari komunitasnya. Dalam memahami fenomena tersebut, pengamatan langsung, baik dalam karnaval maupun dalam media sosial dilakukan. Selain itu, wawancara kepada penggemar dilakukan. Wawancara dilakukan pada saat karnaval digelar di Desa Bagelenan Kabupaten Blitar dan di Desa Purwodadi Kabupaten Kediri. Tulisan ini bertujuan memahami fenomena pawai miniatur truk sebagai sebuah praktik sosial. Untuk melakukan hal teresebut digunakan teori Praktik Sosial Pierre Bourdieu. Penelitian menunjukkan bahwa terdapat modal ekonomi, modal simbolik, dan modal budaya yang digunakan penggemar dalam melakukan praktik miniatur truk. Segala aktivitas ini disebut sebagai konsep habitus. Modal dan habitus yang dimiliki oleh penggemar miniatur tersebut mereka mainkan ke dalam sebuah arena, di mana arena merupakan tempat pertarungan para penggemar dalam merebutkan sumber daya. Pembahasan ini menemukan sebuah konsep baru tentang praktik sosial dalam hiburan masyarakat rural, yaitu pawai miniatur truk telah menjadi sebuah praktik sosial warga pedesaan di daerah Jawa Timur Selatan.
Preserving Local Literary Community: Literary Planning and Policy as a Cultural Strategy in Indonesia
Authors: Afdholy Nadya , Ahmadi Anas , Murti Ghanesya Hari
Published: April 2021

The development of literary communities in Indonesia which spread in every region receive less attention from the government. Literary communities can continue to productively produce works but struggle to survive. This article aims to providing recommendations related to planning and policy to overcome various kinds of Indonesian literary, especially problems in international arena, regional potentials, literary contests, or historiographic documentation of Indonesian literary works development. Literary communities should be optimally empowered through macro planning and policy to revitalize their self in each region. The author recommends several strategies to revitalize local literary communities, namely forming special institutions from independent governments, noting and archiving the development of the literary community from year to year, and setting aside grants for the literary community in each region. This recommendation is expected to overcome the problem of Indonesian literature in international arena.
“Cidade Vigiada”, “Cidade Civilizada”: impressões sobre a difícil convivência entre o progresso e a pobreza no Recife Imperial (1830 – 1850)
Authors: Morais Grasiela Florêncio
Published: April 2021

Esse trabalho tem como cenário o Recife da primeira metade do século XIX (1830-1850), uma cidade que se pretendia moderna e civilizada. Para isso, contou com as ações empreendidas pelas autoridades citadinas para propor e impor projetos de melhoramentos materiais e morais à capital da província. Ao lado do progresso que se queria imprimir no Recife havia a pobreza que se fazia ostensiva e se espraiava pelos redutos da cidade. Os sujeitos que viviam na pobreza, por sua vez, além de sofrerem com as restrições de sua condição ainda estavam submetidos à vigilância cotidiana das autoridades, portanto o diálogo entre esses atores era tenso. Para discutirmos sobre a temática, nos debruçamos sobre os manuscritos da Câmara Municipal do Recife e das Prefeituras de Comarca, os periódicos Diário Novo e Diário de Pernambuco e os impressos dos Relatórios dos Presidentes de Província.
Entre a essencialidade e a instrumentalidade do patrimônio: valores institucionais e participação social na gestão da conservação urbana
Authors: Cunha Paulo José de Albuquerque Marques da , Lapa Tomás de Albuquerque
Published: April 2021

Este artigo insere-se no debate contemporâneo acerca da Gestão da Conservação Urbana baseada nos valores patrimoniais. Em vista da dicotomia entre valores essenciais e valores instrumentais, a Conservação tem encontrado entraves associados às missões das instituições que gerem os sítios patrimoniais e aos processos participativos. Quão efetivos se mostram os mecanismos de gestão compartilhada? Para análise dessa problemática, adota-se o Parque Metropolitano Armando de Holanda Cavalcanti, situado na região Nordeste do Brasil, cuja conservação esbarra no conflito entre residentes e gestores, alcançando resultados insignificantes. Analisam-se o processo de tombamento do Parque e os planos de ações elaborados em 2010 e 2018, com o objetivo de identificar como a participação dos entes relacionados ao bem patrimonial tem contribuído para a tomada de decisão. Para lograr êxito nos processos de conservação, há que se alinhar os discursos com as realidades locais e garantir a efetiva participação dos atores envolvidos.
Fuzzy Translations of A Fuzzy Set in UP-Algebras
Authors: Iampan Aiyared
Published: April 2021

In this paper, we apply the concept of fuzzy translations of a fuzzy set to UP-algebras.For any fuzzy set $\mu$ in a UP-algebra,the concepts of fuzzy $\alpha$-translations of $\mu$ of type \textrm{I} and of fuzzy $\beta$-translations of $\mu$ of type \textrm{II} are introduced, their basic properties are investigated and some useful examples are discussed.The concepts of prime fuzzy sets and of weakly prime fuzzy sets in UP-algebras are also studied.Moreover, we discuss the concepts of extensions and of intensions of a fuzzy set in UP-algebras.
First Eigenvalues of Geometric Operator under The Ricci-Bourguignon Flow
Authors: Azami Shahroud
Published: April 2021

Let $(M,g(t))$ be a compact Riemannian manifold  and  the metric $g(t)$ evolve by the Ricci-Bourguignon flow. We find the formula variation of the eigenvalues of  geometric operator $-\Delta_{\phi}+cR$ under  the Ricci-Bourguignon flow, where  $\Delta_{\phi}$  is the Witten-Laplacian operator and $R$ is the scalar curvature. In the final  we show that some quantities dependent to the eigenvalues of  the geometric operator are  nondecreasing along the Ricci-Bourguignon flow on  closed manifolds  with nonnegative curvature.
Certain Bipolar Neutrosophic Competition Graphs
Authors: Akram Muhammad
Published: April 2021

Different competitions of the real world have been designed by the bipolar neutrosophiccompetitions graphs. In this paper, we first introduce the concept of p-competition bipo-lar neutrosophic graphs. We then define generalization of bipolar neutrosophic competitiongraphs called m-step bipolar neutrosophic competition graphs. Further, we present somerelated bipolar neutrosophic graphs, including m-step bipolar neutrosophic neighbourhoodgraphs, bipolar neutrosophic economic competition graphs and m-step bipolar neutrosophiceconomic competition graphs. Finally, we describe an application of m-step bipolar neutro-sophic competition graphs.
2-Farthest orthogonality in generalized 2-normed spaces
Authors: Mazaheri Hamid , Abad Mousavi Shams , Dehghan M. A.
Published: April 2021

In this paper, we consider the concepts 2-farthest orthogonalityin generalized 2-normed spaces, We obtain a necessary and coecient conditionsfor 2-remotal sets and 2-uniquely remotal sets in generalized 2-normedspaces.
Star Projective and Star Injective Hv-Modules
Authors: Mortazavi A. , Davvaz Bijan
Published: April 2021

In this paper, we introduce the concepts of product and directsum, star projective and star injective in $H_v$-modules. Weinvestigate generalizations of some notions in homological algebrato prove the five lemma and star projective and star injectivetheorems in $H_v$-modules. We determine  equivalent conditions for split sequences in $H_v$-modules and  present some related results.
On Ideals of Bi-Algebras
Authors: Ahn S. S , Ko J. M , Saeid Arsham Borumand
Published: April 2021

In this paper, we discuss normal subalgebras in BI-algebras and obtain the quotient BI-algebra which is useful for the study of structures of BI-algebras. Moreover, we obtain several conditions for obtaining BI-algebras on the non-negative real numbers by using an analytic methods.
Metric Dimension of Graph Join P2 and Pt
Authors: Haryanto Loeky , Nurdin Nurdin , Hasmawati Hasmawati
Published: April 2021

The following metric dimension of join two paths $P_2 + P_t$ is determined as follows. For every $k = 1, 2, 3, ...$ and $t = 2 + 5k$ or $t = 3 + 5k$, the dimension of $P_2 + P_t$ is $2 + 2k$ whereas for $t = 4 + 5k, t = 5(k+1)$ or $t = 1 + 5(k+1)$, the dimension is $3 + 2k$. In case $t \geq 7$, the dimension is determined by a chosen (maximal) ordered basis for $P_2 + P_t$ in which the integers 1, 2 are the two consecutive vertices of $P_2$ and the next integers $3, 4, ..., t + 2$ are the $t$ consecutive vertices of $P_t$. If $t \geq 10$, the ordered binary string contains repeated substrings of length 5. For $t < 7$, the dimension is easily found using a computer search, or even just using hand computations.
The Probability That an Ordered Pair of Elements is an Engel Pair
Authors: Amiri S.M. Jafarian , Rostami Hojjat
Published: April 2021

Let G be a nite group. We denote by ep(G) the probability that[x;n y] = 1 for two randomly chosen elements x and y of G and some posi-tive integer n. For x 2 G we denote by EG(x) the subset fy 2 G : [y;n x] =1 for some integer ng. G is called an E-group if EG(x) is a subgroup of G for allx 2 G. Among other results, we prove that if G is an non-abelian E-group withep(G) > 16 , then G is not simple and minimal non-solvable.
Complementary Ramsey Numbers
Authors: Munemasa Akihiro , Shinohara Masashi
Published: April 2021

In this paper, we consider a variant of Ramsey numbers which we call complementary Ramsey numbers $\bR(m,t,s)$. We first establish their connections to pairs of Ramsey $(s,t)$-graphs. Using the classification of Ramsey $(s,t)$-graphs for small $s,t$, we determine the complementary Ramsey numbers $\bR(m,t,s)$ for $(s,t)=(4,4)$ and $(3,6)$.
A Firefly Algorithm for Portfolio Optimization
Authors: Lazulfa Indana
Published: April 2021

Portfolio optimization is the process of allocating capital among a universe of assets to achieve better risk – return trade-off. Portfolio optimization is a solution for investors to get the return as large as possible and make the risk as small as possible. Due to the dynamic nature of financial markets, the portfolio needs to be rebalanced to retain the desired risk-return characteristics. This study proposed multi objective portfolio optimization model with risk, return as the objective function. For multi objective portfolio optimization problems will be used mean-variance model as risk measures. All these portfolio optimization problems will be solved by Firefly Algorithm (FA).
MODELLING THE EFFECTS OF HCV PLUS-STRAND RNA INFLUX INTO A CELL DURING HCV REPLICATION
Authors: Hussaini Nafiu
Published: April 2021

This paper presents a sub-genomic Hepatitis C Virus (HCV) replication model which incorporates the rate of influx of HCV plus-strand RNA into Huh-7 cell and monitored its effects. The schematic diagram of HCV replication has been simplified. The model exhibits three equilibrium, namely: trivial equilibrium, healthy equilibrium and endemic equilibrium. Stability analysis of the model shows that the healthy equilibrium is globally asymptotically stable under certain condition. It is shown that increase in the rate of influx, increases the steady state level of total plus strand RNA, synthesized plus strand RNA, replicated plus strand RNA and NS5B in the system. Sensitivity and uncertainty analyses of the model (using the \textit{basic replication number} (${\mathcal R}_0$) as the response function) show that the top three PRCC-ranked parameters are the rate of influx, $k_0$ of HCV plus-strand RNA, the rate of production of translation complex ($T_c$) and the rate of degradation, $\mu_{p}^{cyt}$, of plus-strand RNA $R_{P}^{cyt}$. Furthermore, the distribution of $\mathcal{R}_0$ is between $[0.9999,\, 1.0008]$ with a mean of $\mathcal{R}_{0}=1.0003$.}}
On some properties of Abian's semiring and its zero divisor graphs
Authors: Khatun Sarifa , Sircar Jayasri , Nayeem Sk. Md. Abu
Published: April 2021

In this paper, we have studied some properties of Abian's semiring, especially about the supremum of a subset of an Abian's semiring.  We have also considered the zero divisor graphs of Abian's semiring and found some properties of those graphs.
New Bounds for Distance Energy of A Graph
Authors: Sridhara G. , Kanna Rajesh , Parashivamurthy H.L.
Published: April 2021

For any connected graph G, the distance energy, E_D(G) is defined as the sum of the absolute eigenvalues of its distance matrix.  Distance energy was introduced by Indulal et al in the year 2008. It has significant importance in QSPR analysis of molecular descriptor to study  their physico-chemical properties. Our interest in this article is to establish new lower and upper bounds for distance energy.
Hv-Field of Fractions and Hv-Quotient Rings
Authors: Ghadiri Mansour
Published: April 2021

A larger class of algebraic hyperstructures satisfying the ring (field)-likeaxioms is the class of Hv-rings (Hv-fields). In this paper, we define the Hv-integraldomain and introduce the Hv-field of fractions of an Hv-integral domain. Also, theHv-quotient ring and some relative theorems are presented. Finally, some interestingresults about the Hv-rings of fractions, Hv-quotient rings and the relations betweenthem are proved.
On Soft b-w-Open Sets
Authors: Granados Carlos
Published: April 2021

In this paper, we used the notion of soft w-open sets to introduce and study the concepts of soft b-w-open sets. Moreover, some of their properties are shown. Furthermore, the concepts of soft b-T1 and soft b-T2 spaces are defined.
KAPASITAS PEREMPUAN DI MASA PANDEMI: STUDI CVA PADA PEREMPUAN PERAJIN REYENG
Authors: Umami Rizka Hidayatul
Published: April 2021

This paper discusses the capacities of women during the Covid-19 pandemic. In Indonesia, Covid-19 has changed many aspects. Haphazard policy making also adds to the workload of the community, both in the domestic and public sphere. Women as agents who contribute to providing food needs in the realm of the family are almost never included in policy making, especially during the pandemic. This makes the policies issued cannot accommodate the needs of women. Meanwhile, the unfinished pandemic also exacerbates the subordinate conditions experienced by women. This paper uses a gender analysis model of the Capasities and Vulnerabilities Analysis Framework (CVA) to see the extent of the capacities and vulnerabilities of women crafters of reyeng in Dusun Contong, Ngunggahan Village in the midst of the Covid-19 pandemic. The method used in this research is qualitative-descriptive and data collection was taken by observation and in-depth interviews. The results of this study indicate that women crafters of reyeng during the Covid-19 pandemic were vulnerable due to limited access to aspects of health and social assistance. However, these women also have the capacity and capability to adapt to a pandemic. This capability is evidenced by the ability to use the narrow land around the house to grow vegetables and exchange food and bamboo with other reyeng women craftsmen.
PENGARUH INTELLECTUAL CAPITAL TERHADAP KINERJA KEUANGAN BANK SYARIAH (STUDI PADA PT BANK ACEH SYARIAH)
Authors: Rahmah Annisak Nur , Nanda T. Syifa Fadrizha
Published: April 2021

Penelitian ini bertujuan untuk menguji pengaruh intellectual capital terhadap kinerja keuangan. Penelitian ini mencerminkan akan pentingnya pengungkapan intellectual capital pada laporan keuangan, sehingga dapat meningkatkan kinerja keuangan. Data yang digunakan adalah laporan keuangan Bank Aceh Syariah dari bulan Juli 2015 sampai dengan Desember 2017. Model pengukuran intellectual capital yang digunakan adalah model Pulic, yaitu Value Added Intellectual Coefficient (VAICTM). Secara perkomponen terdiri dari: human capital efficiency (HCE), capital employed efficientcy (CEE), dan structural capital efficiency (SCE). Data dianalisis dengan analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa secara parsial: (1) Human Capital Efficiency (HCE) berpengaruh positif dan signifikan terhadap ROA; (2) Capital Employed Efficientcy (CEE) berpengaruh positif dan signifikan terhadap ROA; dan (3) Structural Capital Efficiency (SCE) berpengaruh negatif terhadap ROA. Secara simultan, intellectual capital yang meliputi human capital efficiency (HCE), capital employed efficientcy (CEE), dan structural capital efficiency (SCE) berpengaruh signifikan terhadap ROA. Kata Kunci: Human Capital, Capital Employed, Structural Capital, ROA
OPERASIONALISASI LEMBAGA KEUANGAN BARU DAN DAMPAKNYA TERHADAP PERTUMBUHAN USAHA MIKRO
Authors: Aulia Rahmat , Ibrahim Azharsyah , Tarigan Ismail Rasyid Ridla
Published: April 2021

Dalam banyak literatur disebutkan bahwa umur perusahaan memberikan dampak yang positif terhadap operasionalisasi usaha. Perusahaan dengan umur yang lebih lama akan lebih berpengalaman dan siap dalam menerapkan berbagai strategi penetrasi pasar. Kajian ini secara umum bertujuan untuk memberikan bukti empiris tentang dampak umur perusahaan terhadap operasionalisasinya dalam pembiayaan terhadap usaha mikro. Lembaga Keuangan Mikro Syariah (LKMS) Mahirah Muamalah Banda Aceh dijadikan sebagai sampel dengan pertimbangan bahwa LKMS ini baru beroperasi kurang dari 2 tahun saat kajian ini dilakukan. Secara khusus, kajian ini bertujuan untuk menganalisis pengaruh LKMS Mahirah Muamalah terhadap pertumbuhan Usaha Mikro Kecil dan Menengah (UMKM) di Kota Banda Aceh. Data penelitian dikumpulkan melalui angket/kuesioner yang disebarkan kepada seluruh nasabah pembiayaan (total sampling). Untuk melihat pengaruh, data penelitian dianalisis dengan metode simple regression. Hasil penelitian menunjukkan bahwa LKMS Mahirah Muamalah tidak memiliki pengaruh yang signifikan terhadap pertumbuhan UMKM di Kota Banda Aceh. Hal ini ditunjukkan oleh nilai R Square pada hasil uji koefisien determinasi 0,006 atau hanya sebesar 0,6% dampak yang diberikan oleh operasionalisasi LKMS Mahirah Muamalah terhadap Pertumbuhan UMKM di Kota Banda Aceh. Hasil ini memperkuat bukti bahwa umur LKMS menjadi salah satu faktor penentu dalam penilaian suatu LKMS baru terhadap pertumbuhan UMKM.
PENGARUH PENGETAHUAN PRODUK DAN WORD OF MOUTH TERHADAP KEPUTUSAN NASABAH MEMILIH BANK SYARIAH
Authors: Maulana Fajar Rezky , Hasnita Nevi , Evriyenni Evriyenni
Published: April 2021

Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh pengetahuan produk dan word of mouth terhadap keputusan nasabah memilih Bank Syariah. Pengumpulan data dalam penelitian ini menggunakan angket/kuesioner dengan sampel berupa nasabah Bank Aceh Syariah KCP Samatiga. Metode yang digunakan dalam penelitian ini adalah analisis regresi linear berganda dengan bantuan software IBM SPSS. Penelitian ini menunjukkan hasil bahwa variabel pengetahuan produk dan word of mouth secara parsial berpengaruh terhadap keputusan nasabah memilih Bank Syariah dimana kedua variabel tersebut memiliki nilai signifikansi <0,05. Kemudian secara simultan, menunjukkan bahwa variabel pengetahuan produk dan word of mouth memiliki pengaruh sebesar 51,5%  terhadap keputusan nasabah memilih Bank Syariah.
Public finance reforms and corporate sector impact: A study of Hungary
Authors: Lentner Csaba , Nagy Vitéz
Published: April 2021

The global financial and economic crisis of 2007 and 2008 entailed a sharp deterioration of fiscal positions worldwide; however, fiscal rules soon tightened up in different countries, and parallelly, budgetary discipline improved. A reconsideration of the fiscal policy was necessary as a sovereign debt crisis evolved as a result of the world economic crisis in several countries of the European Union and the eurozone. The study starts at the government debt map of the old member states of the European Union, to which the Hungarian financial positions outside the eurozone are compared. Then, the components of the new Hungarian public finance regulation, major measures, which resulted in an improvement in line with eurozone positions, are presented in full detail. Our study seeks to prove that because of the Hungarian public finance reforms, the fiscal course has also improved, fitting the trends of developed member states of the EU. Although earlier researches have highlighted that it was not only modified fiscal policies that contributed to the post-crisis debt consolidation process in the countries of the eurozone but also the combined effect of the real interest rate and real growth policy. The uniqueness of the study lies in the regulatory instruments, with which the country – positioned in a socialist planned economy, then demonstrating a weak fiscal discipline and sunk in a fiscal crisis even before the global economic crisis of 2007 and 2008 – has consolidated its positions.
El reto de investigar con pertinencia y calidad en la universidad
Authors: O C Bonetti
Published: April 2021

Es un gran honor para mí esta invitación para compartir con ustedes las palabras de apertura deestas XVII Jornadas de Investigación Científica Clínica Universitaria Reina Fabiola que se realizanen este año muy particular: estamos transitando una Pandemia que implica -entre otras cosas- unametamorfosis singular de la educación superior atravesando todas sus funciones, entre ellas la deinvestigación. Por eso, celebro que puedan concretar estas jornadas remotas porque viendo elexcelente programa que han preparado, estimo que podrán compartir y generar instancias dediálogo e intercambio para profundizar las propuestas que aquí se presentan o analizarposibilidades de nuevas investigaciones. Gran parte de las soluciones en la investigación sobreesta pandemia, seguramente está en los claustros universitarios.
Resistencia a la compresión de Biodentine®: mezcla manual vs. Mecánica
Authors: G F Molina , J Ulfohn , G Arce Brisson , C Boetto , I Mazzola , L Brain Lascano , L M Zaya , M Sainz Aja , C J Pascualini , M Farah , M Farah , R J Cabral
Published: April 2021

INTRODUCCIÓN: La incorporación de innovaciones tecnológicas en determinados materiales dentales,especialmente aquellos que requieren de aparatología específica para su uso y/o cuya pre-dosificaciónimplica el descarte de una porción de su contenido, está condicionada por la relación costo-beneficio delproducto. Según las instrucciones del fabricante, las cápsulas del silicato tricálcico Biodentine®(Septodont) deben activarse mediante el uso de mezcladores mecánicos luego de adicionar las proporcionesexactas del líquido ad-hoc, utilizando la totalidad de cada cápsula de polvo y su respectiva ampolla dellíquido, con un excedente de material considerable, según su indicación. Si bien es posible realizar la mezcladel cemento en forma manual prescindiendo de un amalgamador, una modificación en las recomendacionesdel fabricante podría alterar las propiedades del material.OBJETIVO: Determinar si existen diferencias en la resistencia compresiva de Biodentine® según elmétodo de mezcla utilizado: con activación mecánica y con mezcla manual.MATERIALES Y METODOS: Se confeccionaron probetas cilíndricas de 6 mm de alto por 4 mm dediámetro (n=6) para los dos grupos de estudio A) Biodentine® / Mezcla manual y B) Biodentine® / Mezclamecánica. Las muestras fueron sometidas a la aplicación de una fuerza continua en máquina universal deensayos Digimess RS-8000-5 a una velocidad de carrera de 1 mm/min hasta su ruptura. Se compararon losvalores obtenidos entre los grupos mediante test de Student, determinando diferencias significativas paravalores de p>0,05.RESULTADOS: Los valores medios obtenidos y su desviación estándar fueron A) 52.6 (16.3) MPa y B)65.7 (30.6) MPa respectivamente. La distribución de valores de resistencia a la compresión según el grupode estudio fue levemente superior en el grupo B, aunque las diferencias no fueron significativas (p=3,77).CONCLUSIONES: La mezcla manual no disminuye significativamente la resistencia a la compresión deBiodentine® en comparación al cemento mezclado mecánicamente.
Compromiso cardiovascular y trombótico en COVID-19. Implicancias clínicas y terapéuticas
Authors: R Barcudi , J O Bono , P E Sarmiento
Published: April 2021

La infección por el coronavirus 2019 (COVID 19) producida por el virus SARS Cov2 se caracteriza poruna citocinemia exuberante, inflamación endotelial microvascular y macrovascular que afectapredominantemente el sistema respiratorio, pero hay suficiente evidencia que esta enfermedad,particularmente en sus formas más severas afecta también al sistema cardiovascular entre otros. El objetivode la presente revisión es la descripción de las manifestaciones cardiovasculares y trombóticas de estaenfermedad y sus implicancias clínicas y terapéuticas. Para ello se han hemos seleccionado artículospublicados en pubmed medline relacionados con las manifestaciones cardiovasculares y de enfermedadtromboembólica que complican a los pacientes con COVID 19.La enfermedad cardiovascular preexistente y los factores de riesgo cardiovasculares presentes aumentan lamorbilidad y la mortalidad en esta enfermedad.Las manifestaciones cardiovasculares están dadas por la injuria cardiaca manifestada por el incremento delos niveles de troponina asociadas o no a anormalidades electrocardiográficas y/o ecocardiográficas. Ladisfunción miocárdica ocurre en alrededor del 60 % de los pacientes hospitalizados por COVID-19dependiendo de la población que se evalúe. Las potenciales causas de injuria incluyen: desequilibrio entreoferta y demanda de oxígeno por taquicardia hipotensión, hipoxia resultando en un infarto tipo II, síndromecoronario agudo por ruptura de placa en un medio trombótico e inflamatorio resultando en un infarto tipoI, disfunción microvascular debido a microtrombosis difusa, cardiomiopatía por estrés ( síndrome deTakotsubo), injuria miocárdica no isquémica debido a estado hiperinflamatorio por aumento de citosinas,y por toxicidad viral directa produciendo miocarditis.Por otro lado, los mecanismos trombóticos implicados en el COVID-19 son debidos a un estado dehipercoagulabilidad, en donde el virus promueve la formación masiva de fibrina, lo cual explicaría los altosniveles de dímeros D observados. Esta coagulopatía puede causar diversas complicaciones trombóticas ytromboembólicas arteriales y/o venosas, especialmente en pacientes críticamente enfermos, la patogenia sedebe a lesión endotelial, inmovilización y aumento de protrombina circulante. Esta patología en sus formasmás graves va asociadas a biomarcadores tales como, la troponina de alta sensibilidad, el dimero D y laferritina entre otros, todos ellos son el resultado del compromiso cardiovascular y trombótico del COVID19 constituyéndose también marcadores pronósticos.
Chromosome-scale assembly and whole-genome sequencing of 266 giant panda roundworms provide insights into their evolution, adaptation and potential drug targets
Authors: Han Lei , Lan Tianming , Li Desheng , Li Haimeng , Deng Linhua , Peng Zhiwei , He Shaowen , Zhou Yanqiang , Han Ruobing , Li Lingling , Lu Yaxian , Lu Haorong , Wang Qing , Yang Shangchen , Zhu Yixin , Huang Yunting , Cheng Xiaofang , Yu Jieyao , Wang Yulong , Sun Heting , Chai Hongliang , Yang Huanming , Xu Xun , Lisby Michael , Liu Quan , Kristiansen Karsten , Liu Huan , Hou Zhijun
Published: April 2021

Helminth diseases have long been a threat to the health of humans and
animals. Roundworms are important organisms for studying parasitic
mechanisms, disease transmission and prevention. The study of parasites
in the living fossil giant panda is of great significance for
understanding the adaptation mechanism of roundworms to the host. Here,
we report a high-quality chromosome-scale genome of Baylisascaris
schroederi with a genome size of 262 Mb and 19,291 predicted
protein-coding genes. We found a significant expansion of genes related
to epidermal chitin synthesis and environmental information processing
in roundworms genome. Furthermore, we demonstrated unique genes involved
in essential amino acid metabolism in the B. schroederi genome, inferred
to be essential for the adaptation to the giant panda-specific diet. In
addition, under different deworming pressures, we found that four
resistance-related genes (glc-1, nrf-6, bre-4 and ced-7) were under
strong positive selection in captive population. Finally, 23 known drug
targets and 47 potential target proteins were identified. The genome
provides a unique reference for inferring the early evolution of
roundworms and the mechanisms underlying adaptive. Population genetic
analysis and drug prediction provide insights for revealing the impact
of deworming history on population genetic structure and prevention.
Azathioprine for The Induction Treatment of Connective Tissue Disorder Related Interstitial Lung Disease and Comparison with Cyclophosphamide: a retrospective cohort analysis
Authors: Satış Hasan , Onut Mehmet , Baysan Caner , Salman Reyhan Bilici , Yapar Dilek , Babaoğlu Hakan , Ataş Nuh , Güler Aslıhan Avanoğlu , Karadeniz Hazan , Küçük Hamit , Haznedaroglu Seminur , GOKER BURCU , Öztürk Mehmet Akif , Tufan Abdurrahman , Demirci Nilgün Yılmaz , Türktaş Haluk
Published: April 2021

Objectives: Treatment of connective tissue disease-related interstitial
lung disease (CTD-ILD) remains challenging. The literature related to
the immunosuppressive drugs is very limited in most CTDs and there is no
previously reported study comparing induction regimens in patients with
newly defined ‘interstitial pneumonia with autoimmune features (IPAF),
We aimed to investigate the efficacy of azathioprine (AZA) used in
induction regimens for interstitial lung disease in a variety of
connective tissue disorders including IPAF, and compare it with
cyclophosphamide (CYC) Methods. In a retrospective study, all patients
presented with interstitial lung disease to the rheumatology and/or
pulmonology departments in a tertiary referral centre, between 2009 and
2019. Five major CTD groups were defined; systemic sclerosis, rheumatoid
arthritis (RA), primary Sjögren syndrome (pSS), inflammatory myositis
(IMS) and interstitial pneumonia with autoimmune features (IPAF). All
patients who satisfied one of these and received AZA or CYC for
induction therapy for at least 6 months were included in the study.
Treatment responses at six months and side effects were analyzed.
Results: There were 1351 patients diagnosed with ILD. Of these, 328
patients were identified as CTD-ILD, satisfying the classification
criteria of one of the CTDs. Among these, 57 patients received AZA and
79 patients received CYC for induction therapy. CYC treatment resulted
in a 2.41 % increase in FVC, however, AZA resulted in a 1.44% decline
in FVC predicted (p=0.041). Propensity score matching was used to reduce
selection bias, AZA treatment was related to increased risk of
progression (50% vs 13.5%, p:0.002). Conclusion: CYC is superior to
AZA in induction therapy of CTD-ILD.
Invited commentary for asymmetric dimethylarginine (ADMA): Is it a risk factor in the repair of aortic coarctation?
Authors: Do-Nguyen Chi Chi , Stevens Randy , Ochoa Juan , Throckmorton Amy , Mulinari Leonardo
Published: April 2021

Bas et al. report the clinical measurement, using High Performance
Liquid Chromatography (HPLC), of asymmetric dimethyarginine in two
groups of patients undergoing aortic coarctation repair.
Patho-immunological mechanisms of vitiligo: an integration of the immunogenetic milieu, with innate and adaptive immunities, as triggered by environmental stress factors
Authors: Faraj Safa , Kemp E H , GAWKRODGER DAVID
Published: April 2021

Epidermal melanocyte loss in vitiligo, triggered by stresses ranging
from trauma to emo-tional stress, chemical exposure or metabolite
imbalance, to the unknown, can stimulate oxidative stress in pigment
cells which secrete damage-associated molecular patterns that then
initiate innate immune responses. Antigen presentation to melanocytes
leads to stim-ulation of autoreactive T cell responses, with further
targeting of pigment cell. Studies show a pathogenic basis for cellular
stress, innate immune responses and adaptive immun-ity in vitiligo.
Improved understanding of the aetiological mechanisms in vitiligo has
already resulted in successful use of the Jak-1 inhibitors in vitiligo.
In this review we outline the cur-rent understanding of the pathological
mechanisms in vitiligo, and locate loci to which therapeutic attack
might be directed.
High-quality genome assembly of Chinese shrimp (Fenneropenaeus chinensis) suggests genome contraction and adaptation to the environment
Authors: Wang Qiong , Ren Xianyun , Liu Ping , Li Jitao , Lv Jianjian , Wang Jiajia , Zhang Haien , Wei Wei , Zhou Yuxin , He Yuying , Li Jian
Published: April 2021

A high-quality reference genome is necessary to determine the molecular
mechanisms underlying important biological phenomena; therefore, in the
present study, a chromosome-level genome assembly of the Chinese shrimp
Fenneropenaeus chinensis was performed. Muscle of a male shrimp was
sequenced using PacBio platform, and assembled by Hi-C technology. The
assembled F. chinensis genome was 1,465.32 Mb with contig N50 of 472.84
Kb, including 57.73% repetitive sequences, and was anchored to 43
pseudochromosomes, with scaffold N50 of 36.87 Mb. In total, 25,026
protein-coding genes were predicted. The genome size of F. chinensis
showed significant contraction in comparison with that of other penaeid
species, which is likely related to migration observed in this species.
However, the F. chinensis genome included several expanded gene families
related to cellular processes and metabolic processes, and the
contracted gene families were associated with virus infection process.
The findings signify the adaptation of F. chinensis to the selection
pressure of migration and cold environment. Furthermore, the selection
signature analysis identified genes associated with metabolism,
phototransduction, and nervous system in cultured shrimps when compared
with wild population, indicating targeted, artificial selection of
growth, vision, and behavior during domestication. The construction of
the genome of F. chinensis provided valuable information for the further
genetic mechanism analysis of important biological processes, and will
facilitate the research of genetic changes during evolution.
Non-ribosomal insights into ribosomal P2 protein in Plasmodium falciparum-infected erythrocytes
Authors: Das Sudipta , Roy Bhaskar , Chakrabarty Saswata
Published: April 2021

The enormous complexity of the eukaryotic ribosome has been a real
challenge in unlocking the mechanistic aspects of its amazing molecular
function during mRNA translation and many non-canonical activities of
ribosomal proteins in eukaryotic cells. While exploring the uncanny
nature of ribosomal P proteins in malaria parasites Plasmodium
falciparum, the 60S stalk ribosomal P2 protein has been shown to get
exported to the infected erythrocyte (IE) surface as an SDS resistant
oligomer during the early to mid trophozoite stage. Inhibiting IE
surface P2 either by monoclonal antibody or through genetic knockdown
resulted in nuclear division arrest of the parasite. This very strange
and serendipitous finding has led us to explore more about un-canonical
cell biology and structural involvement of P2 protein in Plasmodium in
the search for a novel biochemical role during parasite propagation in
the human host.
Race as a Factor in Donor Selection and Survival of Children with Hematologic Malignancies Undergoing Hematopoietic Stem Cell Transplant in Florida
Authors: Horn Biljana , Chellapandian Deepak , Lamba Nikhil , Sunkersett Gauri , GalvezSilva Jorge , Ziga Edward , Alperstein Warren , Joyce Micahel , Castillo Paul , Fort John , Zhao Jing , Oshrine Benjamin
Published: April 2021

Background Previous studies have explored post-hematopoietic cell
transplant (HCT) outcomes by race in adults; however, pediatric data
addressing this topic are scarce. Procedure This retrospective registry
study included 238 White (W) and 57 Black (B) children with hematologic
malignancies (HM) receiving first allogeneic HCT between 2010 and 2019
in one of five Florida pediatric HCT centers. Results We found no
differences between W and B children by transplant characteristics,
other than donor type. There was a significant difference in use of
HLA-mismatched donors (HLA-MMD) (53% W, 71% B, p=0.01). When comparing
HLA-MMD use to fully HLA-matched donors, B had RR of 1.47 [95% CI
0.7-3] of receiving a mismatched unrelated donor (MMUD), RR of 2.34
[95% CI 1.2-4.4] of receiving a mismatched related donor (MMRD),
and a RR of 1.9 [95% CI 0.99-3.6] of receiving a mismatched cord
blood donor (MMCBD) HCT, respectively. There was no significant
difference in the incidence of aGVHD (48% W, 35% B), p=0.1 or cGVHD
(19% W 28% B, p=0.1), or primary cause of death. Overall 24-month
survival was 61% [95% CI 54-68%] for W, and 60% [95% CI
38-68] for B children, log-rank p=0.72. While HLA matching improved
survival in W children, the number of B children receiving HLA-matched
HCT was too small to identify the impact of HLA matching on survival.
Conclusions In this contemporary cohort of children with HM we found
that B children were more likely to receive HLA-MMD transplants, but
this did not adversely affect survival or GVHD rates.
A rare case of NXP-2 positive dermatomyositis
Authors:   Department of Internal Medicine, University of Texas Health Science Center San Antonio, Joe R. and Terry Lozano Long School of Medicine, San Antonio, TX, USA, Khan Nariman
Published: April 2021

Dermatomyositis is an idiopathic inflammatory myopathy with variable cutaneous manifestations. Several autoantibodies each with distinct clinical phenotypes are associated with the disease. Here we present the case of a 36-year-old Laotian woman with hypothyroidism who presented with severe proximal and distal muscle weakness, dysphagia, diffuse rash, and anasarca that was diagnosed with NXP-2 (nuclear matrix protein 2) antibody positive dermatomyositis. The patient’s hospitalization was complicated by disease resistant to conventional therapy.
Modified Equation of Impulse for Solitons in an Open Water Channel
Authors:   Department of Medical Physics, The Samara State Medical University, Samara, Russia, Volobuev A. N.
Published: April 2021

On the basis of the certain form of write of an impulse equation the modeling of the solitary waves in the water channel is examined at action of gravitation forces. It is shown that as against an existing method of modelling where the waves propagating from left to right turn out from the equation of an impulse, and from right to left from the continuity equation in the offered technique both waves turn out from the equation of impulse. It is marked that the given method is physically more correct. Calculation of a solitary wave, its velocity and geometrical characteristics is submitted.
The incidence of neuropathic pain symptoms in patients with knee osteoarthritis
Authors: Ivacic Josip , Garipi Enis , Knezevic Aleksandar , Boskovic Nikola
Published: April 2021

Introduction. Pain is the most common symptom of knee osteoarthritis. Until
recently, this pain was referred to as nociceptive pain. However, the
difficulties of pain management in knee osteoarthritis indicate the possible
presence of a neuropathic component. The objective of this study was to
determine how often neuropathic component is part of chronic pain in knee
osteoarthritis. Material and Methods. The study included 417 patients with
knee osteoarthritis. The patients were tested using the Neuropathic Pain
(Douleur Neuropathique) 4 Questions and a Numeric Pain Rating Scale.
Patients were divided into 2 groups. The first group included patients with
a Neuropathic Pain 4 Questions score ? 4, and the second group with a score
< 4. Results. The majority of patients included in this study were females
(301, 72.2%), and most of the patients scored less than 4 in the
questionnaire (231, 55.4%). Among the patients with a score ? 4, 144 (77.4%)
were female, which is significantly higher compared to the group of patients
who scored < 4, 157 (68%) (p = 0.037). There was no statistically
significant difference in age between the two groups (p = 0.231). The
current pain intensity, average pain, and maximum pain during the last 4
weeks were significantly higher in the group with a score ? 4 (p < 0.001).
Conclusion. A significant number of patients with knee osteoarthritis had a
neuropathic component of pain. There were significantly more women in the
group with score ? 4, and this group also reported significantly higher
current, as well as average and maximum pain during last 4 weeks than the
other group.
Allergic rhinitis, part of the allergic respiratory syndrome
Authors: Aleksic Aleksandra , Gnjatic Mirjana , Stupar-Hofman Mirjana , Tomic-Spiric Vesna
Published: April 2021

Introduction. Diseases associated with immunoglobulin E hypersensitivity,
such as allergic rhinitis, may have different clinical expressions. Patients
with allergic rhinitis often have associated diseases, comorbidities, which
supports the concept of allergy as a systemic disease. The aim of this study
was to evaluate the incidence and types of comorbidities in allergic
rhinitis. We also evaluated the possible effects of certain clinical and
demographic parameters on the onset of comorbidities. Material and Methods.
This retrospective, observational, and cross-sectional study included
patients with a clinical diagnosis of allergic rhinitis treated at the
Department of Ear, Nose and Throat in the period from October 2011 to April
2013. The collected data were analyzed using the Statistical Analysis System
(Institute Inc. NC, USA) program, version 9.1.3. Results. The study included
319 patients with allergic rhinitis. Allergic rhinitis was intermittent in
30.7% of cases, persistent in 37.9%, and persistent with seasonal
exacerbation in 31.3% of patients. We found that 86.8% of patients had some
form of comorbidity. The most common were conjunctivitis (50.2%), almost
equal percentage of asthma (29.8%) and chronic rhinosinusitis (28.8%),
followed by otitis media with effusion (8.8%), atopic dermatitis (5.2%),
urticaria (4.1%), and laryngitis (3.8%). Persistent allergic rhinitis, with
persistent nasal obstruction as the dominant symptom, was significantly
associated with chronic rhinosinusitis. Positive family history was
significantly associated with the occurrence of asthma and allergic
rhinitis. Conclusion. The results of our study showed that allergic rhinitis
is rarely an isolated condition and it should always be observed in the
context of the allergic respiratory syndrome.
Patterns of alcohol use among first grade high school students in Novi Sad
Authors: Pekovic Sara , Niciforovic-Surkovic Olja
Published: April 2021

Introduction. Alcohol drinking habits are usually formed during adolescence.
Adolescents most often drink alcohol to fit in with their peers, but
genetics and social modeling are also of great importance. Adolescents who
consume alcohol are more prone to mental disorders as well as risky and
violent behavior. Material and Methods. A cross-sectional study was
conducted among first grade high school students in Novi Sad in December
2017. The final sample included 1,067 participants. For the purpose of this
study, the European School Survey Project on Alcohol and Other Drugs
questionnaire was used. Data were analyzed using the Statistical Package for
the Social Sciences program, version 11.0. Results. Beer is the easiest
alcoholic beverage to obtain for young people in Novi Sad, followed by wine
and spirits. A great number of participants have consumed alcohol at least
once in their lifetime and more than half in the last 30 days, (83.5%) and
(52.6%) respectively. More than a third of participants had an episode of
excessive drinking during the last month. Early onset of drinking was found
among one half of male and a third of female participants. Conclusion. These
results indicate an unfavorable situation when it comes to alcohol
consumption among young people in Novi Sad. Therefore, efforts of the
society that encourage healthy development of adolescents are important, as
well as taking preventive measures in order to reduce the risk of alcohol
abuse among young people.
Serous adenocarcinoma detected in the cervical smear: A case report
Authors: Tadic-Latinovic Ljiljana , Baros Ilija , Batinic-Skipina Danijela , Maric Slavica
Published: April 2021

Introduction. Cytological smear tests of the cervix are routine diagnostic
methods used for detection of precancerous lesions and tumors of the cervix;
they are highly sensitive and specific in the detection of precancerous
squamous intraepithelial lesions. Glandular lesions are much less frequently
found in the cervical smear. The most common glandular lesions detected in
the cervical smear are endocervical and endometrial adenocarcinomas.
Cervical metastases are rare, although there are case reports in the
literature. Case Report. In this case report, we present a 64-year-old woman
with an abnormal cervical smear and postmenopausal metrorrhagia. Numerous
accumulations, as well as individual atypical epithelial cells, were
detected in the cervical smear and a cytological diagnosis of a highgrade
squamous intraepithelial lesion was made based on cytomorphological features
suspicious for invasion (Bethesda Classification, 2014) so a cervical biopsy
and curettage of the endocervical canal were performed. A high-grade serous
adenocarcinoma was diagnosed by histopathological examination of cervical
biopsy and cervical canal curettage specimens, after which a transvaginal
ultrasound examination was performed, which showed tumors on both ovaries
and free fluid in the abdominal cavity. The patient underwent abdominal
hysterectomy with bilateral salpingo-oophorectomy. Histological examination
confirmed high-grade ovarian papillary serous adenocarcinoma with psammoma
bodies. Conclusion. The cytological diagnostic features and criteria for
serous adenocarcinoma in Papanicolaou smears are still vague and
insufficiently defined in the literature, which is the reason for very
common errors in the interpretation, so further research on the
pathogenesis, diagnosis and therapy of this tumor is of great importance.
A Pediatric Case of Abrupt-Onset, Autoantibody-Negative Diabetes With Marked Insulin Resistance Concomitant With COVID-19
Authors: Hoyos-Martinez Alfonso , Hicks Kelly , Patel Tracy , Bell Jennifer , Lin Yuezhen
Published: April 2021

By December 2020, coronavirus disease 2019
(COVID-19) had claimed the lives of more than 200,000 in the United States
alone, with more than 10.8 million people infected (1). As the numbers grow, we
continue to learn that this disease has wide-ranging outcomes of varying severity
affecting multiple organs (2). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the novel virus causing COVID-19,
uses the ACE 2 receptor to enter human cells. This receptor is expressed in 15
different human organs (3). Moreover, it is avidly expressed in the pancreatic
islets, but not on the exocrine pancreas, suggesting that the virus may
directly affect β-cells (3).
Law and Power in Russia: Making Sense of Quasi-Legal Practices
Authors: Cornell Anna Jonsson
Published: April 2021

Abstract: Law and Power in Russia: Making Sense of Quasi-Legal PracticesAnna Jonsson Cornell (Department of Law, Uppsala University, Sweden) reviews Law and Power in Russia: Making Sense of Quasi-Legal Practices by Håvard Bækken (published in 2019 by Routledge).
Social Distinctions in Contemporary Russia: Waiting for the Middle Class Society?
Authors: Aasland Aadne
Published: April 2021

Abstract: Social Distinctions in Contemporary Russia: Waiting for the Middle Class Society?Aadne Aasland (NIBR, Norwegian Institute for Urban and Regional Research, Oslo Metropolitan University) reviews Social Distinctions in Contemporary Russia: Waiting for the Middle Class Society? edited by  Jouko Nikula and Mikhail Chernysh (Routledge, 2020).