bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Repository Corticotropin Injection on Medication Use in Patients With Rheumatologic Conditions: A Claims Data Study
Authors: Myung Gihyun , Nelson Winnie W. , McMahon Maureen A.
Published: June 2017

Background: Currently, specific studies identifying how repository corticotropin injection (RCI) is used in rheumatologic conditions are lacking. This is a first step to familiarize the trends of demographics using RCI as well as other medication use. Objective: RCI may produce anti-inflammatory as well as immune-modulatory effects. The purpose of this study is to examine the demographics of those who use RCI and the change in medication use, specifically prednisone, after RCI initiation. Method: This study used the Symphony Health Solutions (SHA) Claims database from 2008 to 2015. International Classification of Disease, Ninth Revision, codes were used to identify rheumatologic conditions including rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis, and polymyositis. Information including RCI dose and concomitant medication uses was also obtained. Results: A total of 2749 patients with rheumatologic conditions receiving RCI were investigated for demographic information, and a total of 1048 patients with rheumatologic conditions on RCI were examined for medication use. The use of nonsteroidal anti-inflammatory drugs, disease-modifying anti-rheumatic drugs, and biologics overall decreased significantly in all 3 rheumatologic conditions except biologics in dermatomyositis/polymyositis. In addition, mean prednisone dose before and after RCI use significantly decreased one quarter (12 weeks) after RCI initiation. Conclusion: Claims-based study on RCI use indicates that RCI use might reduce use of prednisone, disease-modifying anti-rheumatic drugs, and other biologics. Further prospective study is needed.
Right ventricular dyssynchrony and exercise capacity in idiopathic pulmonary arterial hypertension
Authors: Badagliacca Roberto , Papa Silvia , Valli Gabriele , Pezzuto Beatrice , Poscia Roberto , Reali Manuela , Manzi Giovanna , Giannetta Elisa , Berardi Daniele , Sciomer Susanna , Palange Paolo , Fedele Francesco , Naeije Robert , Vizza Carmine Dario
Published: June 2017

Survival in patients with pulmonary arterial hypertension (PAH) is determined by right ventricular (RV) function adaptation to afterload. How altered RV function impacts on exercise capacity in PAH is not exactly known.

104 idiopathic PAH (IPAH) patients aged 52±14 years underwent a diagnostic right heart catheterisation, a comprehensive echocardiography including two-dimensional speckle tracking for RV dyssynchrony evaluation and a cardiopulmonary exercise test. Multivariate analyses were performed to identify independent predictors of peak oxygen uptake (peakV′O2).

A first multivariate analysis of only resting haemodynamic variables identified cardiac index, right atrial (RA) pressure and pulmonary arterial compliance as independent predictors, with low predictive capacity (r2=0.31; p<0.001). A second multivariate analysis model which considered only echocardiographic parameters but without RV dyssynchrony, identified RV fractional area change (FAC) and RA area as independent predictors with still low predictivity (r2=0.35; p<0.001). Adding RV dyssynchrony to the second model increased its predictivity (r2=0.48; p<0.001). Repetition of the three multivariate analyses in patients with preserved RVFAC confirmed that inclusion of RV dyssynchrony results in the highest predictive capability of peakV′O2(r2=0.53; p=0.001).

A comprehensive echocardiography with speckle tracking-derived assessment of the heterogeneity of RV contraction improves the prediction of aerobic exercise capacity in IPAH.
Fast and robust single PCR for Plasmodium sporozoite detection in mosquitoes using the cytochrome oxidase I gene
Authors: Echeverry Diego F. , Deason Nicholas A. , Makuru Victoria , Davidson Jenna , Xiao Honglin , Niedbalski Julie , Yu Xiaoyu , Stevenson Jennifer C. , Bugoro Hugo , Aparaimo Allan , Reuben Hedrick , Cooper Robert , Burkot Thomas R. , Russell Tanya L. , Collins Frank H. , Lobo Neil F.
Published: May 2017

Background

Molecular tools for detecting malaria-infected mosquitoes with improved practicality, sensitivity and specificity, and high-throughput are required. A common PCR technique used to detect mosquitoes infected with Plasmodium spp. is a nested PCR assay based on the 18s-rRNA gene. However, this technique has several technical limitations, is laborious and time consuming.

Methods

In this study, a PCR-based on the Plasmodium cytochrome oxidase I (COX-I) gene was compared with the 18s-rRNA nested PCR using serial dilutions (330–0.0012 pg) of DNA from Plasmodium vivax, Plasmodium falciparum and Plasmodium knowlesi and with DNA from 48 positive and negative Kenyan mosquitoes (previously detected by using both ELISA and PCR). This assay for Plasmodium spp. DNA detection using the fast COX-I PCR assay was then performed individually on 2122 field collected mosquitoes (from the Solomon Islands) in which DNA was extracted from head and thorax.

Results

The fast COX-I PCR assay took 1 h to run and consistently detected as low as to 0.043 pg of parasite DNA (equivalent to two parasites) in a single PCR, while analyses with the 18s-rRNA nested PCR required 4 h to complete with a consistent detection threshold of 1.5 pg of DNA. Both assays produced concordant results when applied to the 48 Kenyan control samples with known Plasmodium spp. infection status. The fast COX-I PCR identified 23/2122 Plasmodium-infected mosquitoes from the Solomon Islands.

Conclusions

This new COX-I PCR adapted for a single PCR reaction is a faster, simpler, cheaper, more sensitive technique amenable to high-throughput analyses for Plasmodium DNA detection in mosquitoes and is comparable to the 18s-rRNA nested PCR. The improved sensitivity seen with the fast COX-I PCR will improve the accuracy of mosquito infection rate determination.
A promising tool for surgical lipotransfer: a constant pressure and quantity injection device in facial fat grafting
Authors: Song Mei , Liu Yi , Liu Ping , Zhang Xianying
Published: May 2017

Background

The purpose of this study was to preliminarily assess a constant pressure and quantity fat granule injection device for minimal invasive properties in clinic.

Methods

A retrospective controlled study was carried out, from October 2013 to January 2015, on 76 female healthy patients aged between 26 and 53 years at the General Hospital of Lanzhou Military Command, China. To achieve small volume, high thrust, and precision requirements of facial fat grafting, an integrated handheld controller and motor design was adopted, reducing the volume and weight of the fat transplantation injection device. The 76 patients underwent 90 procedures each side of the face; each patient was treated with the aforementioned device on the face’s left side, while a conventional hand-push injection device was used on the right side as control. The outcome was assessed on pre- and postoperative images, with 6-24 months follow-up.

Results

The current device consistently allowed deposition of fat threads at about 55 μL/cm after cannula withdrawal; the volume of fat injected could be precisely adjusted to 0.04 mL/s. This device had the advantages of small-volume injection and convenient operation. The patients exhibited a good, stable shape and a smooth contour line in both sides. The long term satisfaction was higher for the left side than for the right one. Nodules and unevenness occurred only on the right side. Ecchymosis occurred significantly less frequent on the left side than the right one. Intraoperative pain was significantly lower for the left side than the right one.

Conclusions

This device offered superior control compared with the conventional one and constitutes a promising tool for surgeons practicing lipotransfer.
Analytical and experimental studies to obtain electrical resistivity in a small-scaled laboratory test
Authors: Taiwo Saheed Mayowa , Lee Jong-Sub , Yoon Hyung-Koo
Published: June 2017

Electrical resistivity surveys have been used to investigate soil behavior at the microscale, and thus they require a method for obtaining accurate electrical resistivity. The previously suggested geometric factor ignores the dimensions of the electrode due to the scale effect present in field conditions, thus necessitating a more appropriate method to capture reliable electrical resistivity for laboratory tests. Our objective is to suggest an analytical solution to obtain reliable electrical resistivity in laboratory testing. Models are verified through laboratory tests and statistical methods. The relationship between electrical resistance and electrical resistivity is analytically defined by Ohm’s law and Gauss’s flux theorem. Consequently, the underlying importance of electrode capacitance including electrode length and diameter for estimating electrical resistivity is evaluated. In addition to the electrical resistivity estimated based on Ohm’s law (EOL), capacitance based on the single-electrode model (CSM) and the multiple-electrode model (CMM), electrical resistivity based on the conventional calibration method is also addressed. Four-equally spaced electrode probe system is designed to measure the electrical resistance. The estimated electrical resistivity based on each model (EOL, CSM, CMM, and [Formula: see text]) is compared with the electrical resistivity estimated from the conductivity meter to verify the suggested models. The electrical resistivity estimated from EOL shows high reliability. Our results underline the significance of EOL model in the conversion of measured electrical resistance into electrical resistivity in laboratory tests.
Neurologic Complications of Transplantation
Authors: Pruitt Amy A.
Published: June 2017

Purpose of Review: This article describes the diagnosis and management of neurologic problems during hematopoietic cell and solid organ transplantation using time elapsed since transplantation as a guide to expected complications, including drug toxicities, infections, strokes, autoimmune phenomena, disease recurrence, and secondary neoplasms.

Recent Findings: Growing clinical experience in the neurology of transplantation has led to appreciation of the diverse clinical and radiographic spectrum of calcineurin inhibitor–related posterior reversible encephalopathy syndrome (PRES) and progressive multifocal leukoencephalopathy. Novel autoimmune phenomena illustrate the delicate balance between adequate immunosuppression and necessary host inflammatory defenses that can lead to organ rejection. The spectrum of infectious complications has changed with the evolution of new conditioning regimens.

Summary: Neurologic problems remain an important source of morbidity and mortality, both in the immediate transplantation period and for years after the procedure. As perioperative management has reduced the incidence of acute infections, graft versus host disease, and organ rejection, problems of long-term survivors require neurologic input into multidisciplinary management of chronic neurologic conditions impacting quality of life.
Introduction: The Prosaic Imaginary
Authors: Frow John
Published: June 2017

This is the introduction to a special issue of Novel, “The Prosaic Imaginary,” edited by John Frow and Vanessa Smith. The editors ask the question: what is the relationship between the novel's prosaic subject matter and novel reading as an everyday activity? Both parts of this question make familiar assumptions about the novel (that it thematizes the mundane world; that its rise is associated with middle-class literacy and, increasingly, with mass literacy), which we want not so much to question as to explore in greater depth and in their relation to each other. Thus we pose a set of corollary questions: How do the forms of attention and imagining that are fostered by the extended form of the novel correspond to the attention and temporality of everyday life? How are the materiality and mobility of the book (typically a small and portable object) bound up with the kinds of object-worlds the novel imagines? And what kind of theory of the novel can best account for its prosaic quality? We talk about prosaic imaginaries in the plural because we take it as given that the novel form develops a plurality of ways of imagining the secular universe; and the concept of the imaginary also helps us to think about the mundane fantasies with which readers invest their activity.
Spiders have rich pigmentary and structural colour palettes
Authors: Hsiung Bor-Kai , Justyn Nicholas M. , Blackledge Todd A. , Shawkey Matthew D.
Published: May 2017

Elucidating the mechanisms of colour production in organisms is important for understanding how selection acts upon a variety of behaviours. Spiders provide many spectacular examples of colours used in courtship, predation, defence and thermoregulation, but are thought to lack many types of pigments common in other animals. Ommochromes, bilins and eumelanin have been identified in spiders, but not carotenoids or melanosomes. Here, we combined optical microscopy, refractive index matching, confocal Raman microspectroscopy and electron microscopy to investigate the basis of several types of colourful patches in spiders. We obtained four major results. First, we show that spiders use carotenoids to produce yellow, suggesting that such colours may be used for condition-dependent courtship signalling. Second, we established the Raman signature spectrum for ommochromes, facilitating the identification of ommochromes in a variety of organisms in the future. Third, we describe a potential new pigmentary–structural colour interaction that is unusual because of the use of long wavelength structural colour in combination with a slightly shorter wavelength pigment in the production of red. Finally, we present the first evidence for the presence of melanosomes in arthropods, using both scanning and transmission electron microscopy, overturning the assumption that melanosomes are a synapomorphy of vertebrates. Our research shows that spiders have a much richer colour production palette than previously thought, and this has implications for colour diversification and function in spiders and other arthropods.
Tibialis Anterior Muscle Hernia: A Case of Chronic, Dull Pain and Swelling in Leg Diagnosed by Dynamic Ultrasonography
Authors: Sharma Navneet , Kumar Neeraj , Verma Richa , Jhobta Anupam
Published: May 2017

Background: Symptomatic muscle hernias are not uncommon in the lower extremities and are a rare cause of chronic leg pain. They are most commonly seen in the tibialis anterior muscle, occurring through fascial defects, usually after trauma. There are about 200 cases of muscle hernias described in the literature. The diagnosis is challenging as most of the patients present with non-specific chronic leg pain. Dynamic muscle ultrasonography at rest and at stress is often used for the diagnosis.

Case Report: We describe a case of tibialis anterior muscle hernia presenting with persistent dull pain and swelling along the anterior aspect of the leg on straining the leg muscles. Dynamic ultrasonography was performed, which showed a defect in the fascial sheath of the muscle through which the tibialis anterior muscle herniated and produced a focal bulge along the anterior aspect of the leg. Based upon physical examination and dynamic ultrasonographic findings, a diagnosis of tibialis anterior muscle hernia was made.

Conclusions: Tibialis anterior muscle hernia is a rare diagnosis and should be included in the differential diagnosis in a patient with chronic leg pain and swelling. Dynamic ultrasound is crucial in confirming the diagnosis and should be done on straining the muscles of the affected limb.
On the primacy and irreducible nature of first-person versus third-person information
Authors: Tressoldi Patrizio E. , Facco Enrico , Lucangeli Daniela
Published: May 2017

In this essay, we will support the claim that at the current level of scientific advancement a) some first-person accounts cannot be reduced to their third-person neural and psychophysiological correlates and b) that these first-person accounts are the only information to reckon when it is necessary to analyse qualia contents.

Consequently, for many phenomena, first-person accounts are the only reliable source of information available and the knowledge of their neural and psychophysical correlates don’t offer any additional information about them.
Genetic and epigenetic control of gene expression by CRISPR–Cas systems
Authors: Lo Albert , Qi Lei
Published: May 2017

The discovery and adaption of bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems has revolutionized the way researchers edit genomes. Engineering of catalytically inactivated Cas variants (nuclease-deficient or nuclease-deactivated [dCas]) combined with transcriptional repressors, activators, or epigenetic modifiers enable sequence-specific regulation of gene expression and chromatin state. These CRISPR–Cas-based technologies have contributed to the rapid development of disease models and functional genomics screening approaches, which can facilitate genetic target identification and drug discovery. In this short review, we will cover recent advances of CRISPR–dCas9 systems and their use for transcriptional repression and activation, epigenome editing, and engineered synthetic circuits for complex control of the mammalian genome.
Recent advances in understanding lung function development
Authors: Melén Erik , Guerra Stefano
Published: May 2017

Recent years have witnessed critical contributions to our understanding of the determinants and long-term implications of lung function development. In this article, we review studies that have contributed to advances in understanding lung function development and its critical importance for lung health into adult life. In particular, we have focused on early life determinants that include genetic factors, perinatal events, environmental exposures, lifestyle, infancy lower respiratory tract infections, and persistent asthma phenotypes. Longitudinal studies have conclusively demonstrated that lung function deficits that are established by school age may track into adult life and increase the risk of adult lung obstructive diseases, such as chronic obstructive pulmonary disease. Furthermore, these contributions have provided initial evidence in support of a direct influence by early life events on an accelerated decline of lung function and an increased susceptibility to its environmental determinants well into adult life. As such, we argue that future health-care programs based on precision medicine approaches that integrate deep phenotyping with tailored medication and advice to patients should also foster optimal lung function growth to be fully effective.
Semantics for interoperability of distributed data and models: Foundations for better-connected information
Authors: Villa Ferdinando , Balbi Stefano , Athanasiadis Ioannis N. , Caracciolo Caterina
Published: May 2017

Correct and reliable linkage of independently produced information is a requirement to enable sophisticated applications and processing workflows. These can ultimately help address the challenges posed by complex systems (such as socio-ecological systems), whose many components can only be described through independently developed data and model products. We discuss the first outcomes of an investigation in the conceptual and methodological aspects of semantic annotation of data and models, aimed to enable a high standard of interoperability of information. The results, operationalized in the context of a long-term, active, large-scale project on ecosystem services assessment, include:

A definition of interoperability based on semantics and scale;

A conceptual foundation for the phenomenology underlying scientific observations, aimed to guide the practice of semantic annotation in domain communities;

A dedicated language and software infrastructure that operationalizes the findings and allows practitioners to reap the benefits of data and model interoperability.

The work presented is the first detailed description of almost a decade of work with communities active in socio-ecological system modeling. After defining the boundaries of possible interoperability based on the understanding of scale, we discuss examples of the practical use of the findings to obtain consistent, interoperable and machine-ready semantic specifications that can integrate semantics across diverse domains and disciplines.
Antimalarial drugs and the prevalence of mental and neurological manifestations: A systematic review and meta-analysis
Authors: Bitta Mary A. , Kariuki Symon M. , Mwita Clifford , Gwer Samson , Mwai Leah , Newton Charles R.J.C.
Published: June 2017

Background:Antimalarial drugs affect the central nervous system, but it is difficult to differentiate the effect of these drugs from that of the malaria illness. We conducted a systematic review to determine the association between anti-malarial drugs and mental and neurological impairment in humans. Methods:We systematically searched online databases, including Medline/PubMed, PsychoInfo, and Embase, for articles published up to 14th July 2016. Pooled prevalence, heterogeneity and factors associated with prevalence of mental and neurological manifestations were determined using meta-analytic techniques. Results:Of the 2,349 records identified in the initial search, 51 human studies met the eligibility criteria. The median pooled prevalence range of mental and neurological manifestations associated with antimalarial drugs ranged from 0.7% (dapsone) to 48.3% (minocycline) across all studies, while it ranged from 0.6% (pyrimethamine) to 42.7% (amodiaquine) during treatment of acute malaria, and 0.7% (primaquine/dapsone) to 55.0% (sulfadoxine) during prophylaxis. Pooled prevalence of mental and neurological manifestations across all studies was associated with an increased number of antimalarial drugs (prevalence ratio= 5.51 (95%CI, 1.05-29.04); P=0.045) in a meta-regression analysis. Headaches (15%) and dizziness (14%) were the most common mental and neurological manifestations across all studies. Of individual antimalarial drugs still on the market, mental and neurological manifestations were most common with the use of sulphadoxine (55%) for prophylaxis studies and amodiaquine (42.7%) for acute malaria studies. Mefloquine affected more domains of mental and neurological manifestations than any other antimalarial drug. Conclusions:Antimalarial drugs, particularly those used for prophylaxis, may be associated with mental and neurological manifestations, and the number of antimalarial drugs taken determines the association. Mental and neurological manifestations should be assessed following the use of antimalarial drugs.
Easier unit tests and better examples with exampletestr and covr
Authors: Nolan Rory , Padilla-Parra Sergi
Published: May 2017

In spite of the utility of unit tests, most R package developers do not write them. exampletestr makes it easier to start writing unit tests by creating shells/skeletons of unit tests based on the examples in the user's package documentation. When completed, these unit tests test whether said examples run correctly. By combining the functionality of exampletestr with that of covr, having ensured that their examples adequately demonstrate the features of their package, the developer can have much of the work of constructing a comprehensive set of unit tests done for them.
View on our world (some addenda to existing ideas)
Authors: Сарач  , Sarach B.
Published: May 2017

The hypothesis is made: the actually density of the Universe substance both before and after the Big Bang has remained invariable and equal to the Planck value approx. 1097 kg/m3. After the Big Bang the huge number of tiny particles – a neutrino (the gravitating masses) – was formed, the density of which is equal to the specified size. On the basis of the hypothesis the structure, parameters, resulting forces and accelerations of neutrino, nucleons (neutrons and protons), -particles, electrons and photons are estimated.
Microstructure of magnetic field on permanent magnet surface
Authors: Поляков  , Polyakov Petr , Гинзбург  , Ginzburg B. , Каминская  , Kaminskaya T. , Попов  , Popov V.
Published: May 2017

In this case we investigate the NdFeB permanent magnet by the atomic force microscopy. Obtained phase diagrams in the center and on the edge of the sample. We investigate the uniformity of the magnetic structure.
The distortion of the domain structure in the presence of a local magnetic defect in the film materials with a high anisotropy
Authors: Поляков  , Polyakov Petr , Акимов  , Akimov M.
Published: May 2017

The theory of magnetic domain of magnetic ordering in the film material, the presence of magnetic inhomogeneities caused by point defects of the dipole type, taking into account how changes in magnetostatic energy, and changes in the anisotropy energy of a domain wall curved. The analysis of the influence of the parameters determining the change in the energy of the magnetostatic interaction domain structure and the change in the anisotropy energy of a domain wall in the curved shape and the bending of the domain boundary.
INNOVATION IN PERSONNEL MANAGEMENT OF ORGANIZATION
Authors: Тавасиева  , Tavasieva Z. , Позмогов  , Pozmogov A.
Published: May 2017

In modern conditions of managing in the organizations introduction of innovative technologies in the sphere of human resource management becomes

an urgent task. The most important factor of realization of innovative solutions of the tasks arising in modern collectives are personnel innovations. They are

based on need of close interrelation of the development strategy of the company with planning of personnel; to assessment of extent of influence of costs for

work with shots on economic indicators of production; formation of necessary amount of competences, professional skills for effective work in labor market.

The main directions of innovative personnel technologies, and also forms of their realization in a control system are defined. The model of work with innovations

in a personnel management system is offered. Dependences of introduction of innovations in human resource management with the solution of specific

objectives, and also their basic orientations are established. It is claimed that a main goal of in human resource management, is providing the organization

by the employees capable to the innovative ideas and technologies of their embodiment.
TO THE QUESTION OF THE KINETICS OF HEAT RELEASE DURING HYDRATION GYPSUM BINDER (Part I)
Authors: Дребезгова  , Drebezgova Mariya
Published: May 2017

In this article, using isothermal differential microcalorimeter that includes a number of devices for the automatic construction of dependency of dQ/dτ=f(τ) and Q= f(τ) was studied by thermo-kinetic regularities of the intensity and completeness of the early stages of hydration of gypsum binders G-5, G-16 and their combinations (G-5-70 % + G-16-30 %), since their mixing with water.
Joint static and dynamic balance sheet
Authors: Черкай  , Cherkay A.
Published: May 2017

The paper considers an example of the construction of a single static and dynamic balance sheet for solving the problems posed in the Conceptual Basis Financial Statements.
MANAGEMENT MECHANISM FORMATION OF INNOVATIVE INDUSTRY INVESTMENT DEVELOPMENT ADEQUATE TO MODERN CONDITIONS
Authors: Грачева Наталья , Gracheva Natalya
Published: May 2017

Recommendations for using venture capital as an investment of innovative programs and projects of industrial enterprises structures are made. The use of its and extra means is optimized at stages of innovation life cycle. The economic-mathematical model of a possible risk capital appreciation and extra means de-pending on security level of innovative programs and projects by own resources in the form of profit got from released innovations is developed. Options of profit formation depending on the cost of innovations and market demand are considered. The economic-mathematical model reflecting this dependence is of-fered. The economic-mathematical model of receiving profit is developed by option of short-term and long-term turnover of innovations and also methodical ap-proach to distribution of profit on innovative processes between beneficiaries is offered. The economic-mathematical model of determination of innovative efficiency of the enterprise at execution of functions by its structures on production and initiative subject. The options of their work in the conditions of openness for the external environment are investigated. Investment sources of their activity are shown. Recommendations on partnerships formation between industrial enterprises and financial-credit institutions as the bases of innovative industry structures inclusion in this cooperation are made. The principles of their relationship are defined: systemacity, common interests, mutual benefit, stability, knowledge.
USA and Russia: 210 Years of Diplomatic Relations and International Communication
Authors: Райнхардт Р. , Raynhardt R.
Published: May 2017

The article is dedicated to the 210th anniversary of establishment of diplomatic relations between the United States of America and Russia and casts light upon their genesis and development. It provides an acute insight into the key issues of US-Russian agenda within a time span of more than 200 years. Along with giving a holistic picture of the subject, the author focuses on specific cases crucial for understanding the current geopolitical juncture shaped by the interaction of the two nations. With an emphasis on differences in political culture, he outlines the important role of cross-cultural communication within the framework of the respective cases. The findings derived from the historical analysis give grounds for a certain degree of optimism in terms of further development of the relationship between the US and Russia.
Dynamic characteristics of mean type dimension lathe installed on rubber-metal anti-vibration supports
Authors: Денисенко А. , Denisenko A.
Published: May 2017

On the basis of a nonlinear dynamic model of a vibration-proof system at power excitation there are formed amplitude-frequency characteristics of a lathe installed on rubber-metal anti-vibration supports, and an area of efficient vibration isolation is defined. An elastic characteristic of the model is presented as an approximating dependence obtained on the basis of the experimental dependence of support elastic deformation changes upon loading.
В работе изложен финансовый механизм бюджетных организаций, рассмотрена правовая среда финансовой деятельности бюджетных организаций, регламент финансового планирования, представлена методика финансового анализа бюджетных организаций, сформирована совокупность ключевых показателей оценки эффективности деятельности бюджетных организаций, изложены основные положения организации финансовой деятельности бюджетных организаций. Выводы иллюстрируются практическими расчетами.
Authors: Шубина  , Shubina Tatiana
Published: May 2017

This book provides a survey about budgetary organizations’ financial mechanism, provided by Russian reform in 2010. Such features like legislation, financial planning, methods of financial analysis were investigated. Authors created an unique system of kea performance items considering those features and provided methods of estimating the quality of budgetary institutions’ financial management performance. The results are approved by actual financial statement valuations.
History of Tourism: education guidance
Authors: Багдасарян Вардан , Bagdasaryan Vardan , Орлов Игорь , Orlov Igor , Попов Алексей , Popov Aleksey
Published: May 2017

The review of history of world tourism from ancient travel to the current state of tourist branch is presented in the education guidance. Special attention is paid to historical development of tourism in Russia. The tendencies of the world tourism development are traced, the reasons for the historical transformations are explained. The book allows you to see tourism as an independent niche of public communications in different epochs of human history. The education guidance is aimed at bachelors studying in the areas of "Tourism" and "History" (profile "Historical and Cultural Tourism"), also at students in other directions of social and humanitarian training.
Fundamentals of designing intelligent decision support systems in nuclear power engineering
Authors: Башлыков  , Bashlykov Aleksandr , Еремеев  , Eremeev Aleksandr
Published: May 2017

The textbook is devoted to actual problems of using the achievements of modern information technologies, including methods of artificial intelligence, in decision-making in emergency situations at environmentally hazardous facilities, typical examples of which are nuclear power plants. The considered problem area of decision-making in emergency situations is a good example for showing the relevance of importance and complexity of the problem to the applied software and mathematical tools such as intelligent (expert) decision support systems for real-time. The book can be recommended as a textbook for students studying in the areas "Nuclear stations: design, operation and engineering", "Applied mathematics and informatics," Computer science and computer technology", "Automation of technological processes and productions ", as well as for students of other directions, post-graduate students, scientific and engineering staff engaged in the design of modern highly efficient decision support systems for managing complex technical (technological) objects and systems.
Wireless technologies for road transport. Global navigation and positioning of vehicles
Authors: Власов  , Vlasov Vladimir , Мактас  , Maktas Boris , Богумил  , Bogumil Veniamin , Конин  , Konin Igor'
Published: May 2017

The textbook outlines the topics included in the "RPD 3+" educational program, including:
- technology of satellite navigation to monitor and control the movement of road transport;
- positioning technology for road transport;
- technology of forming and processing of navigation signals of GLONASS and GPS global navigation satellite systems;
- comparative characteristics of global navigation satellite systems GLONASS and GPS;
- the time dimension in satellite navigation system. The influence of the receiver’s clock error on the accuracy of an object location measurement.
Effectiveness and maintenance of behavior change and exercise programs on depressive symptoms in older adults
Authors: Borges Lucelia , Meurer Simone , Benedetti Tânia
Published: June 2017

The aim of the study was to compare the effectiveness and maintenance of two health promotion programs on depressive symptoms (DS) of older adults. The research was conducted with the network of primary health care in a southern capital of Brazil. In total, 119 older adult participants were allocated into different groups: behavior change (BCG; n=40), exercise (EG; n=51) and control (CG; n=28), assessed at baseline (A1) and followed-up at three (A2), six (A3) and twelve months (A4). BCG attended "VAMOS – Vida Ativa Melhorando a Saúde” (in English, Active Living Improving Health) program while EG attended aerobic gymnastic sessions. The DS were measured by the Geriatric Depression Scale (GDS-15) and level of physical activity (LPA) through accelerometers. Results show that only BCG reduced the number of older adults with high DS (A1=9; A2=4) and this reduction was maintained after six (A3=3) and twelve months (A4=4). Six older adults became physically active (BCG=3; EG=2; CG=1) after the intervention. However, there was no LPA maintenance after six and twelve months, once the frequency of insufficiently active older adults increased or was similar to baseline. When comparing DS, an interaction was found between group and assessment (F=2.94, p=0.01) for BCG, highlighting the reduction (A1=4.0; A2=2.5) and maintenance (A3=2.6; A4=2.8) of mean DS in this group. The results indicate that behavior change programs may bring benefits to the mental health of older adults and the VAMOS program seems to be a viable option for older adults in the community.
Quality of life of male amateur athletes from Pelotas, Brazil
Authors: Dall'Agnol Cristiano , Silva Rodrigo , Del Vecchio Fabrício
Published: June 2017

The aims of the present study were to assess and compare the health habits and quality of life (QoL) of amateur athletes in different sports. A total of 88 male amateur athletes, engaged in team (n=33), individual (n=30) and combat sports (n=25) aged between 18 and 35 years participated in the experiment. The subjects underwent individual anamnesis and completed the WHOQOL-bref questionnaire to measure QoL. Information on the frequency and duration of training sessions was also collected. According to the findings, team sport athletes consumed more alcoholic beverages, and those from individual sports obtained higher values in the physical (83.7 ± 9.3 vs 76.8 ± 9.5 points, p = 0.03) and environmental domains (73.4 ± 11.6 vs 66.3 ± 8.9 points, p = 0.03) and overall QoL score (81.2 ± 6.7 vs 75.2 ± 7.9 points, p = 0.01), respectively. No correlations were found between QoL domains and time engaged in the sport (r = 0.01; p = 0.91), number of weekly training sessions (r = 0.09; p = 0.39) and session duration (r = -0.06; p = 0.59). Comparison of QoL results with those of the general population revealed higher levels in the physical and psychological components of amateur athletes. In the present study, engaging in sports was associated with higher QoL levels in amateur athletes, particularly in the physical and psychological domains. Moreover, correlations were found between the overall score and domains of QoL.
Estilo de vida e nível de atividade física de indivíduos com dor no ombro atendidos em um serviço público
Authors: Pagioto Jessica , Martins Jaqueline , Souza Cesário , Oliveira Anamaria
Published: June 2017

Esse estudo teve como objetivo caracterizar o Perfil de Estilo de Vida Individual (PEVI) de indivíduos com dor no ombro em relação à atividade física (AF), nutrição, controle do estresse, relacionamento social e comportamento preventivo e verificar a correlação entre o componente AF do PEVI e o domínio de incapacidade avaliado pelo Shoulder Pain and Disability Index (SPADI). Trata-se de um estudo transversal, com 100 indivíduos adultos e idosos com dor no ombro (55,3 ± 12 anos, 83% mulheres) atendidos em um serviço público de fisioterapia em 2015/2016. Os indivíduos responderam ao questionário PEVI e ao SPADI para avaliação da dor e incapacidade do ombro. Os resultados indicam que 84% dos avaliados apresentaram PEVI de regular a ruim (pontuação ≤ 33), sendo positivo (pontuação média = 2 a 3) para comportamento preventivo e relacionamento social em 94% e 53% dos indivíduos, respectivamente. Nos demais componentes, as respostas se concentraram no perfil regular (pontuação média = 1 a 1,99) e positivo, mas o componente AF apresentou o maior número de indivíduos (30%) com perfil negativo (pontuação média < 1) e identificou que a maioria não realiza AF moderada a intensa e exercícios de força e alongamento muscular. Os níveis de incapacidade do ombro e de AF apresentaram uma correlação baixa (-0,179; p=0,040). Em conclusão, indivíduos com dor no ombro apresentam estilo de vida regular, sendo importante incentivar a prática de atividade física para melhora da qualidade de vida.
Efeito de dois ritmos de dança de salão na resposta da pressão arterial pós-exercício: uma comparação entre o samba e o bolero
Authors: Sousa Nuno , Ferreira Daiane , Silveira Ana , Sarmento Grazieli , Bertucci Danilo , Tibana Ramires , Prestes Jonato
Published: June 2017

A dança de salão pode representar uma alternativa de exercício físico para controle da pressão arterial (PA), tanto de forma crônica como aguda. O objetivo foi avaliar e comparar a resposta da PA após uma sessão de samba da gafieira e após uma sessão de bolero. Dezenove mulheres não hipertensas (21,9 ± 3,4 anos e IMC de 21,5 ± 2,5 kg/m2) praticantes da dança de salão avançada foram submetidas a duas sessões experimentais de dança de salão com dois ritmos, bolero e samba de gafieira, sendo avaliada a frequência cardíaca (FC) e a pressão arterial (PA) de repouso, durante as sessões (apenas FC) e a cada 10 min durante 60 min após as sessões. Durante as sessões, a FCmédia atingida no bolero foi 145 ± 15 bpm (78 ± 8 %FCmax) e no samba foi 178 ± 13 bpm (92 ± 6 %FCmax), representando intensidade moderada e vigorosa, respectivamente. No ritmo bolero, após 10 min do final da sessão, a pressão arterial sistólica (PAS) já apresentou valores semelhantes (p > 0,05) ao repouso (112,0 ± 12,9 mmHg), sendo mantidos até 60 min após a dança. No samba, a PAS entre os 30 a 60 min foi menor (p < 0,05) que em repouso (114,0 ± 13,0 mmHg), evidenciando hipotensão pós-exercício. Não foram observadas reduções da pressão arterial diastólica após as danças. O ritmo mais intenso, representado pelo samba, induziu hipotensão pós-exercício, o que não ocorreu com o ritmo bolero, que apresentou apenas uma diminuição do trabalho do miocárdio.
Modeling Gas Markets with Endogenous Long-Term Contracts
Authors: Abada Ibrahim , Ehrenmann Andreas , Smeers Yves
Published: June 2017

Since its initial development, long-term contracts have been associated with the gas industry in all regions of the world. This was also the case in Europe where natural gas trade was, for a long time, dominated by bilateral long-term agreements between producers and midstreamers. These contracts fixed a minimum volume to be exchanged (take or pay) and indexed the gas price using a price formula that usually referred to oil product prices. These arrangements allowed market risk sharing between the producer (who takes the price risk) and the midstreamer (who takes the volume risk). They also offered risk hedging since oil is considered as a trusted commodity by investors. The fall of the European natural gas demand, combined with the increase of the oil price, favored the emergence of a gas volume bubble that caused significant losses for most of the European midstreamers bound by long-term agreements. As a result, the downstream part of the industry brought forward the idea of indexing contracts on gas spot prices. In this paper, we present an equilibrium model that endogenously captures the contracting behavior of both producer and midstreamer, who strive to hedge their profit-related risk. Players can choose between gas forward and oil-indexed contracts. Using the model, we show that (i) contracting can reduce the trade risk for both producer and midstreamer; (ii) oil-indexed contracts should be signed only when oil and gas spot prices are well correlated, otherwise, these contracts hold less interest for risk mitigation; (iii) contracts are best suited when the upstream cost structure is mainly driven by capital costs; and (iv) a high level of risk aversion from the midstreamer might deprive upstream investments and downstream consumer surplus.

The online appendix is available at https://doi.org/10.1287/opre.2017.1599 .
The direct anterior approach in total hip arthroplasty
Authors: Meermans G. , Konan S. , Das R. , Volpin A. , Haddad F. S.
Published: May 2017

Aims

The most effective surgical approach for total hip arthroplasty (THA) remains controversial. The direct anterior approach may be associated with a reduced risk of dislocation, faster recovery, reduced pain and fewer surgical complications. This systematic review aims to evaluate the current evidence for the use of this approach in THA.

Materials and Methods

Following the Cochrane collaboration, an extensive literature search of PubMed, Medline, Embase and OvidSP was conducted. Randomised controlled trials, comparative studies, and cohort studies were included. Outcomes included the length of the incision, blood loss, operating time, length of stay, complications, and gait analysis.

Results

A total of 42 studies met the inclusion criteria. Most were of medium to low quality. There was no difference between the direct anterior, anterolateral or posterior approaches with regards to length of stay and gait analysis. Papers comparing the length of the incision found similar lengths compared with the lateral approach, and conflicting results when comparing the direct anterior and posterior approaches. Most studies found the mean operating time to be significantly longer when the direct anterior approach was used, with a steep learning curve reported by many. Many authors used validated scores including the Harris hip score, and the Western Ontario and McMaster Universities Arthritis Index. These mean scores were better following the use of the direct anterior approach for the first six weeks post-operatively. Subsequently there was no difference between these scores and those for the posterior approach.

Conclusion

There is little evidence for improved kinematics or better long-term outcomes following the use of the direct anterior approach for THA. There is a steep learning curve with similar rates of complications, length of stay and outcomes. Well-designed, multi-centre, prospective randomised controlled trials are required to provide evidence as to whether the direct anterior approach is better than the lateral or posterior approaches when undertaking THA. Cite this article: Bone JointJ 2017;99-B:732–40.
Discharge on the day of surgery following unicompartmental knee arthroplasty within the United Kingdom NHS
Authors: Bradley B. , Middleton S. , Davis N. , Williams M. , Stocker M. , Hockings M. , Isaac D. L.
Published: May 2017

Aims

Unicompartmental knee arthroplasty (UKA) has been successfully performed in the United States healthcare system on outpatients. Despite differences in healthcare structure and financial environment, we hypothesised that it would be feasible to replicate this success and perform UKA with safe day of surgery discharge within the NHS, in the United Kingdom. This has not been reported in any other United Kingdom centres.

Patients and Methods

We report our experience of implementing a pathway to allow safe day of surgery discharge following UKA. Data were prospectively collected on 72 patients who underwent UKA as a day case between December 2011 and September 2015.

Results

A total of 61 patients (85%) were discharged on the same day. The most common reason for failure was logistical; five patients had their operation too late in the day. Three patients failed to mobilise safely, two had inadequate control of pain and one had a leaking wound. The mean length of stay for those who were not discharged on the same day was 1.2 nights (1 to 3). During the same time, 58 patients underwent planned inpatient UKA, as they were deemed inappropriate for discharge on the day of surgery. However, three of these were safely discharged on the same day. Follow-up data, 24 hours post-operatively, were available for 70 patients; 51 (73%) reported no or mild pain, 14 (20%) had moderate pain and five (7%) had severe pain. There were no re-admissions. All patients had a high level of satisfaction.

Conclusion

We found that patients can be safely and effectively discharged on the day of surgery after UKA, with high levels of satisfaction. This clearly offers improved management of resources and financial savings to healthcare trusts. Cite this article: Bone Joint J 2017;99-B:788–92.