bluuebunny/crossref_metadata_2025 huggingface dataset:
Sorting Nexin 9 facilitates podocin endocytosis in the injured podocyte
Authors: Sasaki Yu , Hidaka Teruo , Ueno Takashi , Akiba-Takagi Miyuki , Oliva Trejo Juan Alejandro , Seki Takuto , Nagai-Hosoe Yoshiko , Tanaka Eriko , Horikoshi Satoshi , Tomino Yasuhiko , Suzuki Yusuke , Asanuma Katsuhiko
Published: March 2017

The irreversibility of glomerulosclerotic changes depends on the degree of podocyte injury. We have previously demonstrated the endocytic translocation of podocin to the subcellular area in severely injured podocytes and found that this process is the primary disease trigger. Here we identified the protein sorting nexin 9 (SNX9) as a novel facilitator of podocin endocytosis in a yeast two-hybrid analysis. SNX9 is involved in clathrin-mediated endocytosis, actin rearrangement and vesicle transport regulation. Our results revealed and confirmed that SNX9 interacts with podocin exclusively through the Bin–Amphiphysin–Rvs (BAR) domain of SNX9. Immunofluorescence staining revealed the expression of SNX9 in response to podocyte adriamycin-induced injury both in vitro and in vivo. Finally, an analysis of human glomerular disease biopsy samples demonstrated strong SNX9 expression and co-localization with podocin in samples representative of severe podocyte injury, such as IgA nephropathy with poor prognosis, membranous nephropathy and focal segmental glomerulosclerosis. In conclusion, we identified SNX9 as a facilitator of podocin endocytosis in severe podocyte injury and demonstrated the expression of SNX9 in the podocytes of both nephropathy model mice and human patients with irreversible glomerular disease.
SeqTU: A Web Server for Identification of Bacterial Transcription Units
Authors: Chen Xin , Chou Wen-Chi , Ma Qin , Xu Ying
Published: March 2017

A transcription unit (TU) consists of K ≥ 1consecutive genes on the same strand of a bacterial genome that are transcribed into a single mRNA molecule under certain conditions. Their identification is an essential step in elucidation of transcriptional regulatory networks. We have recently developed a machine-learning method to accurately identify TUs from RNA-seq data, based on two features of the assembled RNA reads: the continuity and stability of RNA-seq coverage across a genomic region. While good performance was achieved by the method on Escherichia coli and Clostridium thermocellum, substantial work is needed to make the program generally applicable to all bacteria, knowing that the program requires organism specific information. A web server, named SeqTU, was developed to automatically identify TUs with given RNA-seq data of any bacterium using a machine-learning approach. The server consists of a number of utility tools, in addition to TU identification, such as data preparation, data quality check and RNA-read mapping. SeqTU provides a user-friendly interface and automated prediction of TUs from given RNA-seq data. The predicted TUs are displayed intuitively using HTML format along with a graphic visualization of the prediction.
Size and stochasticity in irrigated social-ecological systems
Authors: Puy Arnald , Muneepeerakul Rachata , Balbo Andrea L.
Published: March 2017

This paper presents a systematic study of the relation between the size of irrigation systems and the management of uncertainty. We specifically focus on studying, through a stylized theoretical model, how stochasticity in water availability and taxation interacts with the stochastic behavior of the population within irrigation systems. Our results indicate the existence of two key population thresholds for the sustainability of any irrigation system: "Equation missing"or the critical population size required to keep the irrigation system operative, andN* or the population threshold at which the incentive to work inside the irrigation system equals the incentives to work elsewhere. Crossing"Equation missing"irretrievably leads to system collapse.N* is the population level with a sub-optimal per capita payoff towards which irrigation systems tend to gravitate. When subjected to strong stochasticity in water availability or taxation, irrigation systems might suffer sharp population drops and irreversibly disintegrate into a system collapse, via a mechanism we dub ‘collapse trap’. Our conceptual study establishes the basis for further work aiming at appraising the dynamics between size and stochasticity in irrigation systems, whose understanding is key for devising mitigation and adaptation measures to ensure their sustainability in the face of increasing and inevitable uncertainty.
Sequential activation of different pathway networks in ischemia-affected and non-affected myocardium, inducing intrinsic remote conditioning to prevent left ventricular remodeling
Authors: Pavo Noemi , Lukovic Dominika , Zlabinger Katrin , Zimba Abelina , Lorant David , Goliasch Georg , Winkler Johannes , Pils Dietmar , Auer Katharina , Jan Ankersmit Hendrik , Giricz Zoltán , Baranyai Tamas , Sárközy Márta , Jakab András , Garamvölgyi Rita , Emmert Maximilian Y. , Hoerstrup Simon P. , Hausenloy Derek J. , Ferdinandy Péter , Maurer Gerald , Gyöngyösi Mariann
Published: March 2017

We have analyzed the pathway networks of ischemia-affected and remote myocardial areas after repetitive ischemia/reperfusion (r-I/R) injury without ensuing myocardial infarction (MI) to elaborate a spatial- and chronologic model of cardioprotective gene networks to prevent left ventricular (LV) adverse remodeling. Domestic pigs underwent three cycles of 10/10 min r-I/R by percutaneous intracoronary balloon inflation/deflation in the mid left anterior descending artery, without consecutive MI. Sham interventions (n = 8) served as controls. Hearts were explanted at 5 h (n = 6) and 24 h (n = 6), and transcriptomic profiling of the distal (ischemia-affected) and proximal (non-affected) anterior myocardial regions were analyzed by next generation sequencing (NGS) and post-processing with signaling pathway impact and pathway network analyses. In ischemic region, r-I/R induced early activation of Ca-, adipocytokine and insulin signaling pathways with key regulator STAT3, which was also upregulated in the remote areas together with clusterin (CLU) and TNF-alpha. During the late phase of cardioprotection, antigen immunomodulatory pathways were activated with upregulation of STAT1 and CASP3 and downregulation of neprilysin in both zones, suggesting r-I/R induced intrinsic remote conditioning. The temporo-spatially differently activated pathways revealed a global myocardial response, and neprilysin and the STAT family as key regulators of intrinsic remote conditioning for prevention of adverse remodeling.
Autaptic Connections Shift Network Excitability and Bursting
Authors: Wiles Laura , Gu Shi , Pasqualetti Fabio , Parvesse Brandon , Gabrieli David , Bassett Danielle S. , Meaney David F.
Published: March 2017

We examine the role of structural autapses, when a neuron synapses onto itself, in driving network-wide bursting behavior. Using a simple spiking model of neuronal activity, we study how autaptic connections affect activity patterns, and evaluate if controllability significantly affects changes in bursting from autaptic connections. Adding more autaptic connections to excitatory neurons increased the number of spiking events and the number of network-wide bursts. We observed excitatory synapses contributed more to bursting behavior than inhibitory synapses. We evaluated if neurons with high average controllability, predicted to push the network into easily achievable states, affected bursting behavior differently than neurons with high modal controllability, thought to influence the network into difficult to reach states. Results show autaptic connections to excitatory neurons with high average controllability led to higher burst frequencies than adding the same number of self-looping connections to neurons with high modal controllability. The number of autapses required to induce bursting was lowered by adding autapses to high degree excitatory neurons. These results suggest a role of autaptic connections in controlling network-wide bursts in diverse cortical and subcortical regions of mammalian brain. Moreover, they open up new avenues for the study of dynamic neurophysiological correlates of structural controllability.
Polymorphisms and Pharmacogenomics for the Clinical Efficacy of Methotrexate in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis
Authors: Qiu Qi , Huang Jing , Shu Xiaoming , Fan Huizheng , Zhou Youwen , Xiao Cheng
Published: March 2017

Methotrexate (MTX) is widely used and considered a first-line disease modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). Many of the relevant genes have been investigated to estimate the association between gene polymorphisms and MTX effectiveness in RA patients, although inconsistent results have been reported. A systematic review and meta-analysis were performed to identify genetic variants associated with MTX efficacy. A total of 30 publications that included 34 genes and 125 SNPs associated with the transporters, enzymes, and metabolites of MTX or the progression of RA were included in the systematic review (SR), and 21 studies were included in 9 meta-analyses. Associations between MTX response in RA patients in MTHFR 1298A > C (rs1801131), ATIC 347C > G (rs2372536), RFC-1 80G > A (rs1051266), SLC19A1 A > G (rs2838956) and SLC19A1 G > A (rs7499) genetic polymorphisms were found, but not observed between the MTHFR 677C > T (rs1801133), TYMS 28 bp VNTR (rs34743033), MTRR 66A > G (rs1801394), and ABCB1 3435C > T (rs1045642). However, for the polymorphisms not being associated following meta-analysis could still be associated if larger cohorts were used, and studies of other polymorphisms are necessary in large cohorts and a rigorous way, which may provide more accurate results for the effect of the gene polymorphisms on the MTX response.
Genetic signatures of natural selection in a model invasive ascidian
Authors: Lin Yaping , Chen Yiyong , Yi Changho , Fong Jonathan J. , Kim Won , Rius Marc , Zhan Aibin
Published: March 2017

Invasive species represent promising models to study species’ responses to rapidly changing environments. Although local adaptation frequently occurs during contemporary range expansion, the associated genetic signatures at both population and genomic levels remain largely unknown. Here, we use genome-wide gene-associated microsatellites to investigate genetic signatures of natural selection in a model invasive ascidian, Ciona robusta. Population genetic analyses of 150 individuals sampled in Korea, New Zealand, South Africa and Spain showed significant genetic differentiation among populations. Based on outlier tests, we found high incidence of signatures of directional selection at 19 loci. Hitchhiking mapping analyses identified 12 directional selective sweep regions, and all selective sweep windows on chromosomes were narrow (~8.9 kb). Further analyses indentified 132 candidate genes under selection. When we compared our genetic data and six crucial environmental variables, 16 putatively selected loci showed significant correlation with these environmental variables. This suggests that the local environmental conditions have left significant signatures of selection at both population and genomic levels. Finally, we identified “plastic” genomic regions and genes that are promising regions to investigate evolutionary responses to rapid environmental change in C. robusta.
A reduced lymphocyte ratio as an early marker for predicting acute pancreatitis
Authors: Qi Xiuzhong , Yang Fangyong , Huang Haitao , Du Yiqi , Chen Yan , Wang Meitang , Zhu Dezeng , Yue Xiaoqiang , Wang Lina
Published: March 2017

The early diagnosis and severity grading for acute pancreatitis (AP) are difficult to determine because of the complexity and differences in disease process. To date, few studies have investigated the role of lymphocyte ratio (LR) in AP. Therefore, the objective of the present study was to investigate the prognostic value of LR as an indicator in AP, as well as determine an optimal cut-off value for the severity prediction. There were two hundred four patients involved in this study, ninety-two of whom had severe acute pancreatitis (SAP). The LR was analyzed on admission and correlated with severity, which was determined using the Atlanta classification. The optimal cut-off value for LR was generated using receiving operator characteristic (ROC) curves. The results showed that the LR in the SAP group decreased significantly compared to the mild acute pancreatitis (MAP) group (8.82 vs. 13.43). The optimal cut-off value obtained from ROC curves was 0.081, with a sensitivity of 80.4%, a specificity of 53.3%, a positive likelihood ratio of 1.722, and a negative likelihood ratio of 0.368. In conclusion, the LR is obviously related to the condition of AP patients and is valuable for the differential diagnosis of SAP in early stages of AP.
Position and orientation measurement adopting camera calibrated by projection geometry of Plücker matrices of three-dimensional lines
Authors: Xu Guan , Zheng Anqi , Li Xiaotao , Su Jian
Published: March 2017

A position and orientation measurement method is investigated by adopting a camera calibrated by the projection geometry of the skew-symmetric Plücker matrices of 3D lines. The relationship between the Plücker matrices of the dual 3D lines and the 2D projective lines is provided in two vertical world coordinate planes. The transform matrix is generated from the projections of the 3D lines. The differences between the coordinates of the reprojective lines and the coordinates of extracted lines are employed to verify the calibration validity. Moreover, the differences between the standard movement distance of the target and the measurement distance are also presented to compare the calibration accuracy of the 3D line to 2D line method and the point-based method. Furthermore, we also explore the noise immunity of the two methods by adding Gaussian noises. Finally, an example to measure the position and orientation of a cart is performed as an application case of this method. The results are tabled for the reproduction by the readers. The results demonstrate that the line to line method contributes higher calibration accuracy and better noise immunity. The position and orientation measurement adopting the line to line method is valid for the future applications.
Efficient frequency generation in phoXonic cavities based on hollow whispering gallery mode resonators
Authors: Farnesi Daniele , Righini Giancarlo , Nunzi Conti Gualtiero , Soria Silvia
Published: March 2017

We report on nonlinear optical effects on phoxonic cavities based on hollow whispering gallery mode resonators pumped with a continuous wave laser. We observed stimulated scattering effects such as Brillouin and Raman, Kerr effects such as degenerated and non-degenerated four wave mixing, and dispersive wave generation. These effects happened concomitantly. Hollow resonators give rise to a very rich nonlinear scenario due to the coexistence of several family modes.
Striatal phosphodiesterase 10A and medial prefrontal cortical thickness in patients with schizophrenia: a PET and MRI study
Authors: Bodén R , Persson J , Wall A , Lubberink M , Ekselius L , Larsson E-M , Antoni G
Published: March 2017

The enzyme phosphodiesterase 10A (PDE10A) is abundant in striatal medium spiny neurons and has been implicated in the pathophysiology of schizophrenia in animal models and is investigated as a possible new pharmacological treatment target. A reduction of prefrontal cortical thickness is common in schizophrenia, but how this relates to PDE10A expression is unknown. Our study aim was to compare, we believe for the first time, the striatal non-displaceable binding potential (BPND) of the new validated PDE10A ligand [11C]Lu AE92686 between patients with schizophrenia and healthy controls. Furthermore, we aimed to assess the correlation of PDE10A BPND to cortical thickness. Sixteen healthy male controls and 10 male patients with schizophrenia treated with clozapine, olanzapine or quetiapine were investigated with positron emission tomography (PET) and magnetic resonance imaging (MRI). Striatal binding potential (BPND) of [11C]Lu AE92686 was acquired through dynamic PET scans and cortical thickness by structural MRI. Clinical assessments of symptoms and cognitive function were performed and the antipsychotic dosage was recorded. Patients with schizophrenia had a significantly lower BPND of [11C]Lu AE92686 in striatum (P=0.003) than healthy controls. The striatal BPND significantly correlated to cortical thickness in the medial prefrontal cortex and superior frontal gyrus across patients with schizophrenia and healthy controls. No significant correlation was observed between the BPND for [11C]Lu AE92686 in striatum and age, schizophrenia symptoms, antipsychotic dosage, coffee consumption, smoking, duration of illness or cognitive function in the patients. In conclusion, PDE10A may be important for functioning in the striato-cortical interaction and in the pathophysiology of schizophrenia.
Elevated hair cortisol concentrations in recently fled asylum seekers in comparison to permanently settled immigrants and non-immigrants
Authors: Mewes R , Reich H , Skoluda N , Seele F , Nater U M
Published: March 2017

Recently fled asylum seekers generally live in stressful conditions. Their residency status is mostly insecure and, similar to other immigrants, they experience stress due to acculturation. Moreover, they often suffer from traumatization and posttraumatic stress disorder (PTSD). All of these factors can result in chronic maladaptive biological stress responses in terms of hyper- or hypocortisolism and, ultimately, illness. We believe the current study is the first to compare hair cortisol concentration (HCC) of recently fled asylum seekers with PTSD to those without PTSD, and to compare HCC of asylum seekers to HCC of permanently settled immigrants and non-immigrant individuals. HCC of the previous 2 months was compared between 24 asylum seekers without PTSD, 32 asylum seekers with PTSD, 24 permanently settled healthy Turkish immigrants and 28 non-immigrant healthy Germans as the reference group. Statistical comparisons were controlled for age, sex and body mass index. No significant difference in HCC was found between asylum seekers with and without PTSD. However, the asylum seekers showed a 42% higher HCC than the reference group. In contrast, the permanently settled immigrants exhibited a 23% lower HCC than the reference group. We found relative hypercortisolism in recently fled asylum seekers, but no difference between persons with and without PTSD. These findings add to the very few studies investigating HCC in groups with recent traumatization and unsafe living conditions. Contrary to the findings in asylum seekers, permanently settled immigrants showed relative hypocortisolism. Both hyper- and hypocortisolism may set the stage for the development of stress-related illnesses.
New dimensions and new tools to realize the potential of RDoC: digital phenotyping via smartphones and connected devices
Authors: Torous J , Onnela J-P , Keshavan M
Published: March 2017

Mobile and connected devices like smartphones and wearable sensors can facilitate the collection of novel naturalistic and longitudinal data relevant to psychiatry at both the personal and population level. The National Institute of Mental Health’s Research Domain Criteria framework offers a useful roadmap to organize, guide and lead new digital phenotyping data towards research discoveries and clinical advances.
Effects of naltrexone are influenced by childhood adversity during negative emotional processing in addiction recovery
Authors: Savulich G , Riccelli R , Passamonti L , Correia M , Deakin J F W , Elliott R , Flechais R S A , Lingford-Hughes A R , McGonigle J , Murphy A , Nutt D J , Orban C , Paterson L M , Reed L J , Smith D G , Suckling J , Tait R , Taylor E M , Sahakian B J , Robbins T W , Ersche K D ,   ICCAM Platform
Published: March 2017

Naltrexone is an opioid receptor antagonist used in the management of alcohol dependence. Although the endogenous opioid system has been implicated in emotion regulation, the effects of mu-opioid receptor blockade on brain systems underlying negative emotional processing are not clear in addiction. Individuals meeting criteria for alcohol dependence alone (n=18, alcohol) and in combination with cocaine and/or opioid dependence (n=21, alcohol/drugs) and healthy individuals without a history of alcohol or drug dependence (n=21) were recruited. Participants were alcohol and drug abstinent before entered into this double-blind, placebo-controlled, randomized, crossover study. Functional magnetic resonance imaging was used to investigate brain response while viewing aversive and neutral images relative to baseline on 50 mg of naltrexone and placebo. We found that naltrexone modulated task-related activation in the medial prefrontal cortex and functional connectivity between the anterior cingulate cortex and the hippocampus as a function of childhood adversity (for aversive versus neutral images) in all groups. Furthermore, there was a group-by-treatment-by-condition interaction in the right amygdala, which was mainly driven by a normalization of response for aversive relative to neutral images under naltrexone in the alcohol/drugs group. We conclude that early childhood adversity is one environmental factor that influences pharmacological response to naltrexone. Pharmacotherapy with naltrexone may also have some ameliorative effects on negative emotional processing in combined alcohol and drug dependence, possibly due to alterations in endogenous opioid transmission or the kappa-opioid receptor antagonist actions of naltrexone.
Anion-regulated electronic communication in a cyclometalated diruthenium complex with a urea bridge
Authors: Gong Zhong-Liang , Deng Li-Ye , Zhong Yu-Wu , Yao Jiannian
Published: March 2017

Electronic coupling in the urea-bridged cyclometalated diruthenium complex is enhanced by the presence of Br−or Cl−.
Metal uptake and distribution in the zebrafish (Danio rerio) embryo: differences between nanoparticles and metal ions
Authors: Böhme Steffi , Baccaro Marta , Schmidt Matthias , Potthoff Annegret , Stärk Hans-Joachim , Reemtsma Thorsten , Kühnel Dana
Published: March 2017

Quantitative data on nanoparticle and cation uptake are compared in a compartment-specific way and distinct differences between metals were identified.
Metabolic profiling study of shikonin's cytotoxic activity in the Huh7 human hepatoma cell line
Authors: Spyrelli E. D. , Kyriazou A. V. , Virgiliou C. , Nakas A. , Deda O. , Papageorgiou V. P. , Assimopoulou A. N. , Gika H. G.
Published: March 2017

Metabolic profiling employed for the first time on Huh7 cells upon treatment with shikonin could provide insight into the metabolic perturbations induced by shikonin.
A fluorogenic 2D glycosheet for the simultaneous identification of human- and avian-receptor specificity in influenza viruses
Authors: Song Jin-Xing , Tang Xin-Ying , Zhou Dong-Ming , Zhang Wenqing , James Tony D. , He Xiao-Peng , Tian He
Published: March 2017

A duplexed 2D glycosheet has been developed for the simultaneous identification of the dual receptor specificity of a single influenza virus strain in a homogeneous solution.
New Ru(ii) N′NN′-type pincer complexes: synthesis, characterization and the catalytic hydrogenation of CO2 or bicarbonates to formate salts
Authors: Dai Zengjin , Luo Qi , Cong Hengjiang , Zhang Jing , Peng Tianyou
Published: March 2017

A new homogeneous system based on new Ru(ii)-N′NN′ pincer complexes has been successfully applied to the hydrogenation of CO2 to the formate, and complex 4 exhibits the best catalytic efficiency.
Two uranyl heterocyclic carboxyl compounds with fluorescent properties as high sensitivity and selectivity optical detectors for nitroaromatics
Authors: Li Shuang , Sun Li Xian , Ni Jue Chen , Shi Zhan , Xing Yong Heng , Shang Di , Bai Feng Ying
Published: March 2017

Uranyl skeleton compounds showed high sensitivity and selectivity for the detection of nitroaromatics.
Selective C–N coupling reaction of diaryliodonium salts and dinucleophiles
Authors: Ma Chang , Wu Xufeng , Zeng Qingle , Zhou Lihong , Huang Yi
Published: March 2017

Ligand-free copper-catalyzed selectiveN-arylation of dinucleophiles including chiral α-amino amides with diaryliodonium salts as aryl electrophile equivalents was realized. Diaryliodonium salts prefer to react with dinucleophiles at the site of stronger basic amino groups.
Inkjet printing of nanocellulose–silver ink onto nanocellulose coated cardboard
Authors: Hoeng Fanny , Bras Julien , Gicquel Erwan , Krosnicki Guillaume , Denneulin Aurore
Published: March 2017

Conductive inkjet printed cellulose nanocrystals (CNC)–silver based lines.
Polyaniline nanoflowers grafted onto nanodiamonds via a soft template-guided secondary nucleation process for high-performance glucose sensing
Authors: Komathi S. , Gopalan A. I. , Muthuchamy N. , Lee K. P.
Published: March 2017

We demonstrated that the electrochemical glucose biosensor fabricated using glucose oxidase-immobilized polyaniline nanoflower-grafted nanodiamonds exhibits superior performances.
Physico-chemical and biological properties of C60-l-hydroxyproline water solutions
Authors: Semenov Konstantin N. , Meshcheriakov Anatolii A. , Charykov Nikolay A. , Dmitrenko Maria E. , Keskinov Viktor A. , Murin Igor V. , Panova Gayane G. , Sharoyko Vladimir V. , Kanash Elena V. , Khomyakov Yuriy V.
Published: March 2017

This paper presents experimental data on a physico-chemical and biological study of C60-l-hydroxyproline derivative water solutions.
Na2S-influenced electrochemical migration of tin in a thin electrolyte layer containing chloride ions
Authors: Liao Bokai , Wei Lisha , Chen Zhenyu , Guo Xingpeng
Published: March 2017

A schematic diagram of the effect of Na2S concentration on the ECM behavior of tin, from low concentration to high concentration.
SelW protects against H2O2-induced liver injury in chickens via inhibiting inflammation and apoptosis
Authors: Jiang Zhi-Hui , Lin Hong-Jin , Yao Hai-Dong , Zhang Zi-Wei , Fu Jing , Xu Shi-Wen
Published: March 2017

Selenium (Se) is recognized as a necessary trace mineral in animal diets. Se deficiency induces a number of diseases and injuries in chickens including liver damage, which is related to oxidative stress.
Green synthesis of 1-phenyl-1-ortho-xylene ethane in IL and reaction mechanism
Authors: Sun Xuejun , Zhou Xinming , Cao Bobo , Cao Ziping , Fu Hui
Published: March 2017

In this study, 1-phenyl-1-ortho-xylene ethane (PXE) is synthesized in IL and the catalysts used were AlCl3 in 1-butyl-3-methylimidazolium bromide ([BMIM][Br]) or 1-butyl-3-methylimidazolium chloride ([BMIM][Cl]).
Electronic and spatial control over the formation of transient ion pairs during photoinduced electron transfer between proflavine–amine systems in a subpicosecond time regime
Authors: Sengupta Chaitrali , Mitra Piyali , Koley Seth Banabithi , Mandal Debabrata , Basu Samita
Published: March 2017

Probing photoinduced electron transfer (PET) in solution in terms of rate of reaction and reaction free energy is a great challenge in physical chemistry.
Deoxygenation of coal bed methane on LaCoO3perovskite catalyst: the structure evolution and catalytic performance
Authors: Zhao Zhenyang , Wang Li , Ma Jian , Feng Yafen , Cao Xiaoming , Zhan Wangcheng , Guo Yanglong , Guo Yun , Lu Guanzhong
Published: March 2017

Deoxygenation of coal bed methane: the structure evolution and activation of a LaCoO3perovskite catalyst.
PDMS/camphor soot composite coating: towards a self-healing and a self-cleaning superhydrophobic surface
Authors: Sahoo Bichitra N. , Nanda Sonil , Kozinski Janusz A. , Mitra Sushanta K.
Published: March 2017

A novel self-cleaning polymer composite with self-healing ability to self-repair after chemical and mechanical damage using readily available materials like polydimethylsiloxane (PDMS) and camphor soot particles is developed.
Residual oxygen groups in nitrogen-doped graphene to enhance the capacitive performance
Authors: Yu Mengying , Xie Bingqiao , Yang Yang , Zhang Yong , Chen Ying , Yu Weiye , Zhang Shanshan , Lu Luhua , Liu Dong
Published: March 2017

Loosely-constructed nitrogen-doped graphene with favored nitrogen and oxygen structures was prepared for a supercapacitor which delivers excellent capacitance and stability performance.
Hyaluronate modified upconversion nanoparticles for near infrared light-triggered on–off tattoo systems
Authors: Han Seulgi , Beack Songeun , Jeong Sanghwa , Hwang Byung Woo , Shin Myeong Hwan , Kim Hyemin , Kim Sungjee , Hahn Sei Kwang
Published: March 2017

We successfully developed an NIR light-triggered in vivo on–off tattoo system using hyaluronate modified upconversion nanoparticles for various biomedical applications.
Emerging role and recent applications of metabolomics biomarkers in obesity disease research
Authors: Zhang Aihua , Sun Hui , Wang Xijun
Published: March 2017

Metabolomics is a promising approach for the identification of metabolites which serve for early diagnosis, prediction of therapeutic response and prognosis of disease.
CaCO3 thin-film formation mediated by a synthetic protein-lysozyme coacervate
Authors: Son Chaeyeon , Kim Sun Young , Bahn So Yeong , Cha Hyung Joon , Choi Yoo Seong
Published: March 2017

A thin film was formed through in vitro CaCO3 crystallization in the presence of complex coacervates, which was expected to be planar and poorly crystalline CaCO3 guided at the interface of two immiscible liquid phases upon complex coacervation.
Effect of annealing atmosphere on quaternary chalcogenide-based counter electrodes in dye-sensitized solar cell performance: synthesis of Cu2FeSnS4 and Cu2CdSnS4 nanoparticles by thermal decomposition process
Authors: Mokurala Krishnaiah , Mallick Sudhanshu
Published: March 2017

Straightforward synthesis of stoichiometrically controlled quaternary chalcogenide nanoparticles is a challenge. Annealing atmosphere has effect on morphology, elemental composition, electrical properties, electrochemical catalytic activity of the CFTS and CCdTS films.
A long cycle life, high coulombic efficiency iron molten air battery
Authors: Cui Baochen , Xiang Wei , Liu Shuzhi , Xin Hongyu , Liu Xianjun , Licht Stuart
Published: March 2017

Despite the recent advancements in iron molten air batteries, great challenges still remain to realize cycling stability, high energy efficiency and a long-term cycling life.
Investigation of the reaction mechanism of lithium sulfur batteries in different electrolyte systems by in situ Raman spectroscopy and in situ X-ray diffraction
Authors: Zhu W. , Paolella A. , Kim C.-S. , Liu D. , Feng Z. , Gagnon C. , Trottier J. , Vijh A. , Guerfi A. , Mauger A. , Julien C. M. , Armand M. , Zaghib K.
Published: March 2017

In liithium–sulfur battery the lithium metal surface was analyzed by in situ Raman spectroscopy.
Unique allosteric effect-driven rapid adsorption of carbon dioxide in a newly designed ionogel [P4444][2-Op]@MCM-41 with excellent cyclic stability and loading-dependent capacity
Authors: Xue Chunfeng , Zhu Hongye , Du Xiao , An Xiaowei , Wang Enyang , Duan Donghong , Shi Lijuan , Hao Xiaogang , Xiao Bo , Peng Changjun
Published: March 2017

Allosteric effect-driven rapid stepwise CO2 adsorption of pyridine-containing anion functionalized ionic liquid [P4444][2-Op] confined into mesoporous silica MCM-41.
One-pot synthesis of highly efficient MgO for the removal of Congo red in aqueous solution
Authors: Bai Zongquan , Zheng Yajun , Zhang Zhiping
Published: March 2017

Magnesium oxide (MgO) has been demonstrated to be a promising candidate for the treatment of toxic dyes in wastewater due to its unique characteristics (e.g., high isoelectric point, nontoxicity and cost-effectiveness).
Graphene oxide foams: the simplest carbon-air prototypes for unique variable dielectrics
Authors: Hou Zhi-Ling , Liu Xing-Da , Song Wei-Li , Fang Hui-Min , Bi Song
Published: March 2017

At lower and higher frequency, the decoupled and coupled states of the density-dependent dielectric properties were observed in GO foams, which are considered to be the simplest carbon-air prototypes for unique dielectrics.
Intracellular synthesis ofd-aminoluciferin for bioluminescence generation
Authors: Zheng Zhen , Li Gongyu , Wu Chengfan , Zhang Miaomiao , Zhao Yue , Liang Gaolin
Published: March 2017

Chemically stable precursors were employed to intracellularly synthesized-aminoluciferin for bioluminescence generation.
Probe dependence on polar solvation dynamics from fs broadband fluorescence
Authors: Kumpulainen Tatu , Rosspeintner Arnulf , Vauthey Eric
Published: March 2017

Solvation dynamics is remarkably independent of the probe as long as specific interactions remain similar.
Dibenzothiophene-platinated complexes: probing the effect of ancillary ligands on the photophysical performance
Authors: Solomatina Anastasia I. , Aleksandrova Irina O. , Karttunen Antti J. , Tunik Sergey P. , Koshevoy Igor O.
Published: March 2017

Alteration of the ancillary mono- and bidentate ligands was used to influence the photoemission behaviour of a family of cyclometalated platinum complexes.
DFT calculations as a ligand toolbox for the synthesis of active initiators for ROP of cyclic esters
Authors: Jędrzkiewicz D. , Kantorska D. , Wojtaszak J. , Ejfler J. , Szafert S.
Published: March 2017

New heteroleptic zinc dimeric complexes bearing an aminophenolate ligand of a single-site initiator framework were synthesized and characterized by spectroscopic methods, X-ray analysis, and DFT calculations.
Regioselective C8-metalation of N-phosphine tethered adenine derivatives via C8–H activation
Authors: Brackemeyer D. , Schulte to Brinke C. , Roelfes F. , Hahn F. E.
Published: March 2017

Complex [4] obtained from N7-phosphine tethered adenine and [IrCl2Cp*]2 reacts upon heating under C8–H activation to give [7]Cl bearing an adenine derived pNHC^PR3 chelate ligand.
Gastrointestinal absorption, antiproliferative and anti-inflammatory effect of the major carotenoids of Gardenia jasminoides Ellis on cancer cells
Authors: Oliveira Hélder , Cai Xiaoshuang , Zhang Qian , de Freitas Victor , Mateus Nuno , He Jingren , Fernandes Iva
Published: March 2017

Crocetin was the carotenoid with the highest gastrointestinal transport efficiency and the most effective in inhibiting cancer cell proliferation. In addition, this carotenoid showed involvement in the downregulation of the inflammatory cytokines.
Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers
Authors: Qiao Yadong , Yao Zhiyi , Ge Wenqi , Zhang Li , Wu Hai-Chen
Published: March 2017

A sensor based on polyelectrolyte-induced pyrene excimers has been developed for the visual detection of heparin with high sensitivity and selectivity.
Synthesis of a dimeric 3α-hydroxy-7α,12α-diamino-5β-cholan-24-oate conjugate and its derivatives, and the effect of lipophilicity on their anion transport efficacy
Authors: Li Zhi , Chen Yun , Yuan De-Qi , Chen Wen-Hua
Published: March 2017

A dimeric 3α-hydroxy-7α,12α-diamino-5β-cholan-24-oate conjugate and its derivatives were synthesized, and lipophilicity was found to significantly affect their anion transport efficacy.
Cyclic peptide unguisin A is an anion receptor with high affinity for phosphate and pyrophosphate
Authors: Daryl Ariawan A. , Webb James E. A. , Howe Ethan N. W. , Gale Philip A. , Thordarson Pall , Hunter Luke
Published: March 2017

Unguisin A (1) is a marine-derived, GABA-containing cyclic heptapeptide with a high binding affinity for phosphates.
Gold catalysis: synthesis of spiro, bridged, and fused ketal natural products
Authors: Quach Rachelle , Furkert Daniel P. , Brimble Margaret A.
Published: March 2017

This review summarises the application of gold catalysis for the syntheses of spiro, bridged and fused ketal natural products.
Synthesis and characterization of semiaromatic polyamides comprising benzofurobenzofuran repeating units
Authors: Cretenoud Julien , Özen Bilal , Schmaltz Thomas , Görl Daniel , Fabrizio Alberto , Corminboeuf Clémence , Fadaei Tirani Farzaneh , Scopelliti Rosario , Frauenrath Holger
Published: March 2017

Extended π-conjugated segments such as benzofurobenzofuran can be included into polyamides with high glass transition temperatures.
One further step to cell behaviour understanding
Authors: Fang Jiye
Published: March 2017

Self-assembled silver nanowires were applied to SERS-detectable and ordered-substrate-induced cellular growth to understand the stretched bimolecular behaviour.
The influence of oxygen vacancies on the linear and nonlinear optical properties of Pb7O(OH)3(CO3)3(BO3)
Authors: Reshak A. H. , Auluck S.
Published: March 2017

We have investigated the influence of the oxygen vacancy on the linear and nonlinear optical properties and the microscopic first hyperpolarizability of asymmetric Pb7O(OH)3(CO3)3(BO3).
Nanosizing Pd on 3D porous carbon frameworks as effective catalysts for selective phenylacetylene hydrogenation
Authors: Yu Weizhen , Hou Hongshuai , Xin Zhiling , Niu Shuo , Xie Yanan , Ji Xiaobo , Shao Lidong
Published: March 2017

In this work, palladium nanoparticles supported on 3D porous carbon frameworks (Pd/PCFs) were used in the selective hydrogenation of phenylacetylene.
Graphene/TiO2 hybrid layer for simultaneous detection and degradation by a one-step transfer and integration method
Authors: Yu Xinxin , Cai Ranran , Song Yuqing , Gao Qiang , Pan Nan , Wu Mingzai , Wang Xiaoping
Published: March 2017

During the past decades, researchers have made great efforts towards an ideal surface enhanced Raman spectroscopy (SERS) substrate.
Low electrical resistivity of a graphene–AgNHPs based ink with a new processing method
Authors: Liu Piao , Tang Quanzhong , Liu Hua , Lu Anxian
Published: March 2017

AgNHPs was purified with membrane separation-centrifugation cleaning and syntheses the GE–AgNHPs with the low resistivity (2.5 × 10−6 Ω cm) at low temperatures.
A novel polymeric micelle used for in vivo MR imaging tracking of neural stem cells in acute ischemic stroke
Authors: Lu Liejing , Wang Yong , Cao Minghui , Chen Meiwei , Lin Bingling , Duan Xiaohui , Zhang Fang , Mao Jiaji , Shuai Xintao , Shen Jun
Published: March 2017

Novel cationic polymeric micelles based on biodegradable poly(aspartic acid-dimethylethanediamine)–lysine–cholic acid were synthesized for in vivo tracking therapeutic stem cells using MRI.
Nitrogen-doped Fe3C@C particles as an efficient heterogeneous photo-assisted Fenton catalyst
Authors: Yang Xiaoling , Li Chengjia , Huang Jianfei , Liu Yanyan , Chen Wei , Shen Jianhua , Zhu Yihua , Li Chunzhong
Published: March 2017

The oxygen in Fe3O4 nanoparticles was replaced by carbon and nitrogen from the graphitic carbon nitride fragments released from dicyandiamide condensation.
One-pot hydrothermal synthesis of novel 3D starfish-like δ-MnO2 nanosheets on carbon fiber paper for high-performance supercapacitors
Authors: Xu Bin , Yu Lin , Sun Ming , Ye Fei , Zhong Yuanhong , Cheng Gao , Wang Hui , Mai Yuliang
Published: March 2017

Novel 3D starfish-like δ-MnO2 nanosheets with a hierarchical nanostructure supported on carbon fiber paper were synthesized through a facile hydrothermal method.
Highly emissive carbazole-based gold(i) complex with a long room-temperature phosphorescence lifetime and self-reversible mechanochromism characteristics
Authors: Chen Zhao , Liu Gang , Wang Renjie , Pu Shouzhi
Published: March 2017

A gold(i) complex with long room-temperature phosphorescence lifetime has been reported. The luminogen exhibits self-reversible mechanochromic behavior.
Ansavaricins F–I, new DNA topoisomerase inhibitors produced by Streptomyces sp. S012
Authors: Zhang Zhiqiang , Wu Xingkang , Song Rentai , Zhang Juanli , Wang Haoxin , Zhu Jing , Lu Chunhua , Shen Yuemao
Published: March 2017

Ansamycins are a family of macrolactams characterized by an aromatic chromophore with an aliphatic chain (ansa chain) connected back to a nonadjacent position through an amide bond.
Highly selective hydrodeoxygenation of anisole, phenol and guaiacol to benzene over nickel phosphide
Authors: Li Yunhua , Fu Juan , Chen Binghui
Published: March 2017

Ni2P supported catalysts have extensively been studied for various hydrodeoxygenation (HDO) reactions to benzene at a higher reaction temperature and lower H2 pressure.
Bright green emission from f-MWCNT embedded co-doped Bi3+ + Tb3+:polyvinyl alcohol polymer nanocomposites for photonic applications
Authors: Kumar K. Naveen , Padma R. , Ratnakaram Y. C. , Kang Misook
Published: March 2017

A bright, dazzling green emission has been obtained from functionalized multi walled carbon nanotube (f-MWCNT)-embedded Bi3+ + Tb3+:PVA polymer nanocomposites under UV excitation.
Underlying mechanism of blue emission enhancement in Au decorated p-GaN film
Authors: Qin Feifei , Chang Ning , Xu Chunxiang , Zhu Qiuxiang , Wei Ming , Zhu Zhu , Chen Feng , Lu Junfeng
Published: March 2017

Our research explains the defect-related LSP generation, coupling, electron transfer, and further light emission enhancement of Au decorated GaN.
Toward a detoxification fabric against nerve gas agents: guanidine-functionalized poly[2-(3-butenyl)-2-oxazoline]/Nylon-6,6 nanofibers
Authors: Ying Wu Bin , Kim Sohee , Lee Min Woo , Go Na Yeong , Jung Hyunsook , Ryu Sam Gon , Lee Bumjae , Lee Kyung Jin
Published: March 2017

A novel guanidine-functionalized polymer, poly[2-(3-butenyl)-2-oxazoline] (PBuOxz), has been co-electrospun with Nylon-6,6 to form fibers that could be used for the decontamination of chemical warfare agents (CWAs).
Microwave-enhanced catalytic wet peroxide oxidation of quinoline: the influence of pH and H2O2dosage and identification of reactive oxygen species
Authors: Zhang Bo , You Hong , Wang Fei
Published: March 2017

This article presents a study about the initial pH and H2O2dosage influence on TOC abatement by MW-CWPO with Cu/Ni-catalyst and reactive oxygen identification based on quinoline mineralization inhibition using the specific radical scavengers.
Enhanced photoelectrochemical performance of tungsten oxide film by bifunctional Au nanoparticles
Authors: Kong Yueqi , Sun Honggang , Fan Weiliu , Wang Li , Zhao Hongkai , Zhao Xian , Yuan Shengzhong
Published: March 2017

Proposed mechanism of the synergistic effect of SPR and inner electric field in the Au/WO3.
Optimization of performance and long-term stability of p-type dye-sensitized solar cells with a cycloruthenated dye through electrolyte solvent tuning
Authors: Marinakis Nathalie , Willgert Markus , Constable Edwin C. , Housecroft Catherine E.
Published: March 2017

The balance between optimal photoconversion efficiency and long-term stability in p-type DSCs with a cyclometallated ruthenium dye is presented, with mixtures of acetonitrile and propionitrile being the best solvent with an I3−/I− redox couple.
Catalytic hydrotreatment of bio-crude produced from the hydrothermal liquefaction of aspen wood: a catalyst screening and parameter optimization study
Authors: Yu Jinlong , Biller Patrick , Mamahkel Aref , Klemmer Maika , Becker Jacob , Glasius Marianne , Iversen Bo Brummerstedt
Published: March 2017

Hydrocarbon fuel (alkanes and aromatics) production via catalytic hydrotreatment of bio-crude from pilot scale HTL.
Synthesis, structure, and optoelectronic properties of II–IV–V2materials
Authors: Martinez Aaron D. , Fioretti Angela N. , Toberer Eric S. , Tamboli Adele C.
Published: March 2017

II–IV–V2materials offer the promise of enhanced functionality in optoelectronic devices due to their rich ternary chemistry.
Electrospinning and mechanical properties of P(TMC-co-LLA) elastomers
Authors: Cork Jorja , Whittaker Andrew K. , Cooper-White Justin J. , Grøndahl Lisbeth
Published: March 2017

P(TMC-co-LLA) elastomers have shown great potential for various biomaterial and tissue engineering applications.
In vivo toxicological assessment of electrochemically engineered anodic alumina nanotubes: a study of biodistribution, subcutaneous implantation and intravenous injection
Authors: Wang Ye , Zinonos Irene , Zysk Aneta , Panagopoulos Vasilios , Kaur Gagandeep , Santos Abel , Losic Dusan , Evdokiou Andreas
Published: March 2017

First pilot toxicity study on anodic alumina nanotubes in immune-competent murine models.
Insights into Li+-induced morphology evolution and upconversion luminescence enhancement of KSc2F7:Yb/Er nanocrystals
Authors: Wang Yangbo , Wei Tian , Cheng Xingwen , Ma Hui , Pan Yue , Xie Juan , Su Haiquan , Xie Xiaoji , Huang Ling , Huang Wei
Published: March 2017

Li+ doped KSc2F7:Yb/Er nanocrystals show greatly enhanced upconversion red luminescence that is good for deep tissue imaging.
Improving adult day services through technology: a user‐based approach
Authors: Calvillo‐Arbizu Jorge , Roa‐Romero Laura M. , Estudillo‐Valderrama Miguel A. , Vera‐Vera Joaquin
Published: March 2017

Adult day services (ADS) are receiving increased attention due to shifts in health and social policies encouraging home and community‐based services for an aging population. However, some issues hinder ADS effectiveness such as the need of diversification of interventions focused on elderly people (with different needs and dependency levels) or the undertrained staff. This work presents an analysis of current ADS gaps from interviews to Spanish geriatric experts and scientific literature. An innovative user‐based technology implementation is approached to address the most relevant missing gaps identified: formal assessment of user's skills and status before joining the ADS, establishment of personalised interventions for each user, user classification on groups according to characteristics of user members etc. This approach allows to assess elderly over time to generate knowledge about his/her psychological and physical conditions and about the general factors that accelerate/delay deterioration caused by age.
Nanosecond pulse discharge based nitrogen oxides treatment using different electrode configurations
Authors: Mohapatro Sankarsan , Allamsetty Srikanth , Madhukar Apeksha , Sharma Nikhil Kumar
Published: March 2017

Nowadays, the intensity of air pollution, due to the industries and automobiles, has been increasing continuously. Nitrogen oxides (NOX) are one of the most harmful pollutants, which are getting released from both automobile and stationary diesel engines. They essentially need to be removed from the exhaust using after treatment systems. However, the energy required to remove these pollutants is one of the major considerations in selecting the technology for pollutant removal from diesel engine exhaust. A study has been carried out on the non‐thermal plasma‐based NOX removal technique using various combinations of power supply units and electrode configurations. Three different electrode configurations are tested, in which two are cylindrical electrodes with diameters 3 and 5 mm, and the other one is a square electrode with a diagonal of 5 mm. A comparison is made between the results with two different pulse power supply units, PS‐I: high‐voltage direct current test set based and PS‐II: DC–DC converter based. The square electrode with PS‐II has been found to be the optimal combination, which has removed 85% of NOX from the exhaust at an energy density of 55.5 J/L, when the initial NOX concentration in the exhaust is 388 ppm.
Robust and sparse canonical correlation analysis based L2,p ‐norm
Authors: Shi Zhong‐rong , Wang Sheng , Liu Chuan‐cai
Published: March 2017

The objective function of canonical correlation analysis (CCA) is equivalent to minimising an L 2 ‐norm distance of the paired data. Owing to the characteristic of L 2 ‐norm, CCA is highly sensitive to noise and irrelevant features. To alleviate such problem, this study incorporates robust feature extraction and group sparse feature selection into the framework of CCA, and proposes a feature fusion method named robust and sparse CCA (RSCCA). In RSCCA, L 2,p ‐norm is adopted as the distance measurement of paired data, which can alleviate the effect of noise and irrelevant features and achieve robust performance. The experimental results show that our method outperforms CCA and its variants for feature fusion.