bluuebunny/crossref_metadata_2025 huggingface dataset:
Impacto del programa “Donante Power” en la donación voluntaria de sangre del Perú
Authors: Pérez Lizbeth , Magallanes Sebastián Martín Gaspar , Cango Shelah , Martínez Angely , Tiparra Ana , Zúñiga Katherine , Arevalo Sheyla , Pizarro Eckert
Published: August 2021

Por la escasa donación voluntaria de sangre en el Perú y sumado al contexto de pandemia, los bancos de sangre se han visto mermados en las cantidades de unidades disponibles, por lo cual se evaluó el impacto de un programa de sensibilización sobre la donación voluntaria de sangre. Previo al inicio del programa, se aplicó una evaluación inicial para todos los inscritos y al finalizar las 10 charlas que fueron transmitidas por Google meet y Facebook live, se invitó a todos los inscritos a volver a completar otra vez la evaluación. Se aplicó la prueba de rangos de Wilcoxon obteniendo p=0.03 (p<0,05) para el nivel de conocimiento y p=0.21 (p<0,05) para el nivel de actitudes. Se concluye que el programa “Donante Power” sí presenta cambios significativos positivos hacia la donación de sangre.
Optimasi Sistem Photovoltaik Menggunakan Cuk Konverter Berbasis Simple Perturb and Observe Method
Authors: Sulis Tatit , Fathoni Fathoni , Putri Ratna
Published: August 2021

Mengingat indonesia merupakan negara tropis, ketersediaan energi matahari cukup melimpah di Indonesia karena musim kemarau berlangsung selama 6 bulan. Photovoltaik juga dapat digunakan sebagai sumber energi listrik di daerah terpencil yang masih belum terjangkau oleh PLN. Rancangan Cuk konverter dipilih karena mampu menurunkan dan menaikkan tegangan sumber dari photovoltaik 200WP. Kelebihan cuk konventer mampu mengurangi ripple pada keluaran PV yang dapat menyebabkan tegangan akan lama mencapai konstan. Metode MPP tracking yang terkenal adalah metode perturb and observe (P&O). PWM digunakan untuk mengontrol konverter dan mengontrol tegangan yang di inginkan. Hasil pengujian tegangan masukan power supply 12V. dengan duty cycle 10% menghasilakan tegangan  1.99V. Sementara hasil pengujian masukan power supply 12V, dengan duty cycle 60% menghasilkan tegangan 11.59V. Penerapan P&O pada cuk konverter dirasa cukup efektif pada sistem photovoltaik dengan hasil yang cukup stabil dengan rata-rata keluaran tegangan 23,848 Volt.

Kata kunci: Photovoltaik, Cuk Konverter, PWM, P&O.
Residential Electricity Consumers and Increasing Block Pricing Policy in Pakistan: Evidence Based on Household Level Primary Data
Authors: Malik Sania
Published: August 2021

The purpose of this paper is to explore the efficacy of increasing block electricity pricing (IBEP) which was imposed in 2013 by the Pakistani government. The main objective of this policy is rational resource allocation and to lower the cross-subsidization to the residential sector by two other major sectors such as commerce and industry. The study is based on primary data which is collected through questionnaires from four tehsils of district Sargodha in rural as well as the urban regions. About 54.6% of households understand the electricity price scheme (IBEP) while urban users are more aware as compared to rural but urban electricity consumption is higher due to high use of home appliances. By using the regression model the elasticity of residential electricity consumption is estimated for heterogeneous consumers. The upper blocks of electricity consumption are more sensitive to price increases (e.g., the elasticity of the first to fourth block is -0.391, -0.988, -1.229, -0.955 respectively) except in the fifth block (-0.489) which indicates that higher income group pays more attention to the standard of living. The increase in the number of trees also affects the price elasticity of residential electricity use and positively influences saving behaviour. The policy which was implemented from a welfare point of view has achieved its target to a certain extent. Future guidelines for the up-gradation of electricity pricing reform in the residential sector are thus proposed.
Human Capital Sustainability and Organizational Performance: The Case of a Travel Agency
Authors: Balian Patrick , Ghaleb Elias
Published: August 2021

The tourism industry in the Middle East plays a critical role in maintaining and energizing countries' economic status. It has a major element in facing numerous human capital obstacles that are deepening its development. This paper seeks to explore how the enhancement of human capital in a travel agency can have a significant positive impact on its performance, by studying the importance and consequences of the enhancement of human capital to improve specifically a travel agency's performance. This research aims to identify and remedy the delinquencies in the enterprise’s human capital that are obstructing its growth performance. We utilized the socio-economic methodology, which is a mix of qualitative, quantitative, and financial approaches, to remediate the organizational transition from within the travel agency at all stages and with the participation of all the members in the enterprise. The research study focuses on human capital dimensions across metrics for maximizing performance effectiveness that endorsed our hypothesis: “Enhancement of human capital improves travel agency firm’s performance”. The results of this intervention research add to the literature of the human capital variable of intellectual capital theory, which previous authors did not explore, by providing considerable contributions to the field of intellectual capital in a specific set of metrics. It demonstrated a positive impact on the travel agency firm’s performance through the enhancement of Human capital through time management, sales activity, marketing, and communication skills enhancement.
Uso do Design Thinking para o Desenvolvimento e Construção de Projetos Educacionais em Saúde utilizando Tecnologias de Informação e Comunicação
Authors: Souza Thaúsi Frota Sá Nogueira Neves , Pereira Daniel Vale , Azevedo Cláudio Roberto Freire de
Published: August 2021

Objetivo: relatar a experiência de utilização do Design Thinking como proposta metodológica para o desenvolvimento e construção de projetos educacionais utilizando Tecnologias de Informação e Comunicação pelos educadores do Núcleo de Educação Permanente do SAMU 192 – Regional Fortaleza. Metodologia: trata-se de estudo descritivo, de natureza qualitativa, baseado em relato de experiência do uso do Design Thinking por seis educadores do serviço, no período de março a junho de 2020. O desenvolvimento e construção dos projetos educacionais ocorreu à distância, através de aplicativo para videoconferências, utilizando as fases de inspeção, ideação e implementação do Design Thinking. Resultados: a utilização do Design Thinking aumentou o potencial reflexivo e criativo do grupo, através do uso do pensamento abdutivo associado aos pensamentos convergente e divergente, o que culminou com a construção de material educacional autoinstrucional. Considerações Finais: essa experiência permitiu ao grupo desenvolver um trabalho baseado na aprendizagem colaborativa à distância, de forma a aplicar, analisar, sintetizar e criar produtos no ambiente virtual de aprendizagem, de forma a ampliar as ofertas de propostas educacionais do serviço para a educação à distância, contribuindo assim, para melhor qualificação da Educação Permanente no município de Fortaleza.
Nuestrapraxis. Suplemento
Authors:   Universidad Autónoma Metropolitana-Cuajimalpa / ANEICJ, Sandoval-Cervantes Daniel , Melgarito Blanca , Correas Oscar , Avendaño Lukas , Salazar Cynthia
Published: August 2021

Nuestrapraxis. Entrevistas: Constitución y Revolución. Conferencia de clausura de la 3a. Jornada de la Conferencia de Crítica Jurídica, Quito, Ecuador, 2013. Por: Oscar Correas; transcripción Daniel Sandoval Cervantes. Nuestrapraxis. Literaria: Poema por Lukas Avendaño Nuestrapraxis. Gráfica: Migrantes y racismo estructural por Blanca Estela Melgarito Nuestrapraxis. Publireportaje: Segunda Jornada de la VII Conferencia Latinoamericana de Crítica Jurídica por Daniel Sandoval-Cervantes
EL PROGRAMA DE RESIDENCIA PEDAGÓGICA EN LA PANDEMIA DEL COVID-19: informes de profesores de Biología en formación inicial
Authors: Ramos Ratis Liliana , De Andrade Soareas Adriele , Lima da Silva Ximenes Érica , Alves Pereira Maria das Graças , Matos Paula Valdemar
Published: August 2021

Al informar sobre la educación en este período pandémico, se observa que no solo fue el método de enseñanza el que sufrió cambios, de la enseñanza presencial a la enseñanza a distancia, sino también la percepción de los estudiantes sobre los procesos de enseñanza y aprendizaje. Hablando de los estudiantes de educación superior, especialmente los de los cursos de pregrado, se observa que incluso durante la Pandemia se buscó hacer posible la “permanencia” en la educación a distancia. Por ello, pensando en esta y otras demandas existentes dentro de la formación del futuro docente, este trabajo tiene como objetivo discutir el papel del Programa de Residencia Pedagógica (PRP) en la construcción de una mirada crítica y reflexiva de los licenciados en Biología, desde el Instituto Federal. de Educación, Ciencia y Tecnología de Acre (IFAC), durante el período de la pandemia Covid-19. Para la realización de este estudio se adoptó una metodología en el formato de informe, así como un análisis documental que pudiera sustentar la redacción de este estudio y el conocimiento del PRP, además, fue fundamental la concepción de los estudiantes de pregrado a través de observaciones durante la participación en el PRP. para la construcción de este informe. Se encontró que las actividades del PRP dificultaban de forma remota la observación de la práctica docente por parte de los docentes en la formación inicial. Sin embargo, el Programa ayuda al estudiante a comprender cómo se lleva a cabo el trabajo de enseñanza y presenta los desafíos de enseñar Biología en tiempos de pandemia.
The Effect of Using WhatsApp on the Jordanian 5th Grade EFL Students' Speaking Skill
Authors: AlAzzam-Khraiwish Amin Ali , Bataineh Ahmed M. , Alzyod Ayman H.
Published: August 2021

The aim of this study is to investigate the effect of using WhatsApp on developing fifth grade EFL students’ speaking skill during the first semester of the academic year 2020-2021. To achieve this purpose, the researchers selected carefully a representative sample of 46 male students studying at Jijin Secondary School for Boys. The participants were already divided into two groups; a control group of 21 students and an experimental one of 25 students.This study tended to apply this experiment by using the quasi-experimental method. The instrument was a performance test in a shape of an interview that was used as a pre-test and a post-test. Moreover, this test was used to measure any possible differences between the both groups. The results of the study indicated that there were statistically significant differences between both of the groups and the mean scores, in favor of the experimental one in speaking due to the suggested strategy of using WhatsApp.In the light of the findings, the researchers recommend the necessity of implementing contemporary strategies such as WhatsApp in teaching and learning English speaking skill. Besides, the researchers suggest that further studies should be conducted on the effect of WhatsApp on developing other English language skills and in other language competences.
Optimization of aqueous extraction conditions for bioactive compounds from fresh Pouzolzia zeylanica plant using response surface methodology
Authors: Nguyen Tan D.
Published: August 2021

Response surface methodology was applied to optimize the extraction of phenolic compounds from fresh Pouzolzia zeylanica plant using hot water as a solvent. A central composite design (CCD) in form (23+star) was used to investigate the effects of two independent variables, namely, extraction temperature (70 to 90oC) and extraction time (20 to 40 min). The dependent variables were the content of anthocyanin, flavonoid, polyphenol, tannin and total soluble solids of extracted solution. A second-order polynomial model was used for predicting the response. The results showed that the optimal extraction process was obtained at 84.4oC for 31.7 min. The experimental values agreed with predicted within a 95% confidence interval. Consequently, the contents of anthocyanin, flavonoid, polyphenol and tannin were 38.66 mgCE/100 g, 3.01 mgQE/g, 5.17 mgGAE/g, 4.07 mgTAE/g fresh weight, and total soluble solids content was 0.73%, respectively.
The effects of plant spacing on yield and quality of butterfly pea (Clitoria ternatea L.) cultivated in organic-oriented farming system on grey soil
Authors: Duong T. T. Pham
Published: August 2021

Clitoria ternatea L. is a plant species that can be used in food and pharmaceutical industry. This study was conducted to evaluate the effects of different plant spacing on the productivity and quality of butterfly pea grown on grey soil in Thu Duc, Ho Chi Minh City. Six treatments correspond to plant spacing of 80 x 15 cm, 80 x 20 cm, 80 x 25 cm, 80 x 30 cm, 80 x 35 cm and 80 x 40 cm. The results showed that the highest flower amount (296.8 flowers/plant) was obtained with butterfly pea planted at the spacing of 80 x 15 cm, commercial flower weight (7.86 g/100 flowers), theoretical yield of fresh flower (1,779.0 kg/1,000 m2, actual yield of fresh flower (841.9 kg/1,000 m2), theoretical yield of commercial flower (194.6 kg/1,000 m2 and actual yield of commercial flower (89.0 kg/1,000 m2. Nevertheless, plant spacings did not affect the dry matter ratio, anthocyanin and tannin content in the commercial butterfly flowers
Antibiotic sensitivity of common respiratory bacteria of pig from Hubei province, China
Authors: Nguyen Anh L. L.
Published: August 2021

The use of antimicrobials for feeding and treatment is crucial to animal health. However, continuous use of antibiotics is contributing to emergence and widespread of antibiotic resistance. This study aimed to investigate the antimicrobial resistance of five major respiratory pathogens in pigs of Hubei province, China, from October to December, 2019. Antibiotic susceptibility testing for Streptococcus suis, Haemophilus parasuis, Pasteurella multocida, Bordetella bronchiseptica and Actinobacillus pleuropneumoniae was determined to representatives of relevant antibiotic classes. Streptococcus suis isolates were mostly sensitive to beta-lactams, whereas high levels of resistance were observed to quinolones, gentamycin, doxycycline, trimethoprime and lincomycin. For H. parasuis, P. multocida and A. pleuropneumoniae of Pasteurellaceae family, the susceptibility to beta-lactams and quinolones was displayed. Most B. bronchiseptica isolates were sensitive to doxycycline azithomycin, polymycin whereas high resistance levels to betalactams, aminoglycosides and quinolones were recorded. This study obtained practical data for later studies and usage to combat infections due to respiratory bacteria.
Infection status of Mycoplasma hyopneumoniae in experimental pigs at a commercial farm
Authors: Bui Huyen T. N.
Published: August 2021

The objective of this study was to investigate the profiles of Mycoplasma hyopneumoniae (MH) infection at different ages of pig in a sow – finishing herd using serological and molecular methods. A total of 30 study piglets were born from non-vaccinated sows with MH. They were injected one-dose of inactivated MH vaccine at the 10th week. MH infection status was evaluated by using ELISA to detect MH antibodies from blood samples, and PCR to detect MH DNA in nasal swabs or oral fluid samples every other week from newborn to slaughter time. The results of this study showed that PCR positive proportions were low at 1st-2nd week (7-13%), then increased significantly during 5th -7th week (73-79%) and reduced at 8th week (33%); finally became negative after 13th week of age. This pattern corresponds to the one of antibody level. In particular, the level of maternal antibodies against MH was very high due to maternal immunity, then decreased gradually to negative at 7-8 weeks of age, and finally increased gradually from 13 weeks of age to all positive at 25 weeks of age. In conclusion, the result showed that in this herd, MH might invade pigs by the time of 5-7 weeks of age after maternal immunity disappears, and humoral response can overcome the infection at week 13. This should be noted to have appropriate strategies to control MH at the farm.
Application of polypropylene mesh on bilateral perineal hernia: A case study
Authors: Luong Dat Q.
Published: August 2021

The protuberance of pelvic viscera is due to the weakness or failure of pelvic diaphragm muscles called a perineal hernia. The etiology of this disease involved in this process was poorly determined but associated with multi-factors which included gonadal hormone imbalance, rectal abnormalities, prostatic disease, and myopathy. Additionally, the prevalence of middle age and old dogs overwhelmed the young ones due to the change in livelihood and diet. Although there was a certain rate of success in treatment for perineal hernia, this disease had high proportions of recurrence and postoperative complications. This study was conducted at Sasaki Animal Hospital in Ho Chi Minh City to manage this disease by the synthetic mesh implant. A 10-year castrated male Pomeranian (5.2 kg) was referred to clinical examination because of a 4-month complaint of the return of a mass at the perineal area. The owner also reported constipation and hematuria with the presence of pus. Rectal palpation and radiography indicated that the bladder contained in the hernia sac. Ultrasound showed that the bladder contained a large clump of pus. Blood test and antimicrobial-resistant test were also performed by taking the blood and urine with a pus sample, respectively. The ill animals were treated for bacterial infection and then operated to relocate hernia by polypropylene mesh. After 14-day operation, the results were considered satisfactory, which the perineal area returned to normal without any complications. However, the recurrence of this non-infectious disease was reported to range from 10-46%. Therefore, the following health check was necessary to perform twice within a year.
Seroprevalence against classical swine fever virus in vaccinated pigs in Ho Chi Minh City
Authors: Duong Mai C.
Published: August 2021

The aim of this study was to survey the serological response to classical swine fever disease in vaccinated pigs in Cu Chi, Ho Chi Minh City. By using the PrioCHECK® CSFV Ab 2.0 ELISA test kit to detect antibodies against CSF in 410 vaccinated pigs and IDEXX CSFV Ag Serum Plus Test to detect the Erns protein of the CSFV in pigs without antibodies against CSFV. Results showed that the overall seroprevalence observed in vaccinated pigs in other Farms varied from 70% - 100% (P < 0.05), but in Farm 5, no pigs produced a positive humoral response against CSFV were found. The highest seroprevalence of antibodies against CSFV was found in Farms with a herd size of ≥ 1000 - < 6000 animals (91.26%) and the lowest was a Farms with less than 1000 animals (51.81%). The highest ratio of positive pigs for antibodies against CSFV belonging to Group of > 40 - ≤ 60 days post-vaccination was 98.36%. The lowest rate was found in Group of 30 - ≤ 40 days postvaccination (51.96%). That grower pigs had the highest proportion of positive pigs for antibodies against CSFV accounting for 81.40%; next, the proportion of positive sows was 73.24%. Significant differences in the seroprevalence observed in vaccinated pigs across herd size, days post-vaccination, type of pigs (P < 0.05). In this study, no pig was found to contain CSFV antigen.
Accumulation and distribution of heavy metal cadmium in sweet sorghum
Authors: Dinh Tra T. T.
Published: August 2021

Many species of plants have been studied, as well as applied for cleansing the environment. Previous research has concluded that sorghum plants are highly tolerant to metal pollution and capable of reaching high biomass values in the presence of metals. However, the distribution of heavy metals in plant’s parts has not been adequately studied. In this study, two varieties of sweet sorghum (Keller and E-Tian) were grown with 5 levels (0, 5, 10, 25 and 50 ppm) of cadmium (Cd) in order to investigate the accumulation of Cd in plant parts at the hard dough stage. The results clearly showed the absence of Cd in the seeds of the above plants. There was the presence of Cd at the second and fifth leaf when the level of Cd reached 25 - 50 ppm. There was a great correlation coefficient between Cd and the position of the internodes, namely 0.86, 0.96, 0.99, 0.98 with KE, and 0.86, 0.92, 0.94, 0.94 with ET at 5, 10, 25 and 50 ppm Cd (P < 0.01), respectively. The greater the internodes, the lower the accumulation of Cd. The aforementioned plants recorded the high accumulation of Cd in their roots, peaking at 23.27 μg/g (dried weight, dw) in Keller and 21.69 μg/g in E-Tian. Based on these results, it is concluded that the distribution of Cd in the studied sweet sorghum can be arranged in the following order: > stem > old leaves > young leaves
Antiplasmodial effects of Allium sativum extract on haematological Parameters of Albino Wistar rats infected with Plasmodium berghei
Authors: Joy Nkeiruka Dike-Ndudim  , Chizaram Winners Ndubueze
Published: August 2021

This study aimed at evaluating the antiplasmodial effects of Allium sativum (bulbs) on haematological parameters of albino rats infected with Plasmodium berghei, divided the animal model into groups, viz: the experimental group (with five different concentrations of 100, 300, 500, 800 and 1000mg/kg), the normal-control (non-inoculated), negative-control (inoculated, but untreated) and positive control (inoculated and treated with 10mg/kg Combisunate). Allium sativum ethanolic extracts were administered and monitored for four days before the treatment. Afterwards, the average parasitaemia was calculated and the average percentage parasite inhibition (suppressive effect) was obtained. Result showed that the parasitemia level for the treated groups decreased progressively for the five-day period. This is indicative in the mean number of the percentage parasitized red cells of 1000mg/kg doses as 9.055±2.06 on the first day post inoculation and 0.30±0.04 on the fifth day. The decrease is also observed in the 100, 300, 500 and 800mg/kg groups. Except the untreated group which showed a progressive increase in parasitemia level with average percentage parasitized red cells as 11.33±1.97 on the first day post inoculation and 18.15±1.49 on the fifth day. The haematological result showed a significant (p<0.05) decrease in values of RBC, PCV, Hb, and neutrophils in the inoculated groups, especially the untreated group. As compared to the treated groups, these parameters showed progressive increase as concentrations increased. Conclusively, it can be inferred that the bulbs of Allium sativum have antiplasmodial potentials and can therefore be purified for development of antimalarial drugs.
Outcome of Sellar and Suprasellar Brain Tumors with Retractorless Modified Subfrontal Approach
Authors: Rauf Abdul , Khan Hameed Ullah , Hussain Mubarak
Published: August 2021

Aim: To determine the outcome of sellar and suprasellar brain tumors with retractorless modified subfrontal approach. Study design: Descriptive/observational study Place and duration of study: Department of Neurosurgery, Liaquat University Hospital Hyderabad/Jamshoro from 1st March 2020 to 28th February 2021. Methodology: Fifty patients of sellar and suprasellar brain tumors age between 15-70 years were enrolled. Patients details demographics age, sex and body mass index were recorded after taking written consent. The inter-hemispheric front-basal technique was used for all patients and the average follow-up time was 6 months. Postoperatively, magnetic resonance imaging (MRI) and computerized tomography (CT) scans in all patients were performed. After 12 hours, the postoperative CT scan was performed to monitor for persistent tumor and hemorrhage cerebral edema following an operation. Results: There were 30 (60%) male patients and 20 (40%) female patients. Mean age of the patients were 28.36±14.88 years with mean BMI 23.16±7.54 kg/m2. Most of the patients 20(40%) were from age group 15-30 years, followed by 31-40 years in 12 (24%) patients. Frequency of pituitary adenoma was found in 22 (44%) cases, craniopharyngioma found in 19 (38.7%) cases, arachnoid cyst found in 4 (8%), keratin flakes in 2 (4%) cases, benign giant cell tumor found in 2 (4%)olfactory groove meningioma in 1 (2%) and epidermoid in 1 (2%) cases. Post operatively 35 (70%) patients were completely recovered, complications found in 13 (26%) patients who were recovered later and frequency of not recovered patients was 2 (4%). According to Karnofsky performance, 16 (32%) patients had scale 30, scale 60 was in 2 (4%) cases, scale 70 in 4 (8%) patients, scale 80 in 19 (38%) and scale 90 in 9 (18%). Conclusion: This retractorless method is very effective and safe in the sellar and suprasellar region for excision of big tumors. This method allows the huge tumor to be removed without serious complication. Keywords: Sub-frontal approach, Sellar, Suprasellar, Brain tumor, Retractorless method
A Study of Molar Pregnancy at Low Resource Settings of Tertiary Care Hospital Sindh
Authors: Fatima Sabahat , Shaikh A. G.ul , Mahar Tahmina , Bozdar Hameed-Ur-Rehman , Memon Sameena , Khokhar Mahjabeen
Published: August 2021

Aim: To determine the epidemiological factors/characteristics and clinical presentation of molar pregnancy Study design: Qualitative observational / retrospective study Place and duration: Department of Obstetrics and Gynaecology Unit-II, Ghulam Muhammad Mahar Medical College Sukkur from 1st January 2016 to 31st December 2020. Methodology: Forty five diagnosed cases with molar pregnancy and aged between 18-40 years were enrolled. Patient’s details demographics age, body mass index, parity and socio economic status were recorded. The total birth records and gynecological admission for the study period were also collected from the gynaecology and labour room record books case and operational registration data were obtained, descriptive statistics examined . Results: Mean age of the patients was 31.15±7.41 years with mean body mass index 26.16±7.22 kg/m2. Mean gestational age of the patients were 25.62±9.19 weeks. Twenty seven (60%) patients were multiparous and 18 (40%) were primiparous. 30 (66.7%) were illiterate and 15(33.3%) cases were literate. There were 14(31.11%) patients belonged lower class, 18 (40%) patients belonged middle and 13(28.9%) had high socioeconomic status. Twenty nine (64.4%) were from rural area and 16 (35.6%) were from urban area. Five (11.1%) patients had previous history of gestational trophoblastic disease. Abnormal vaginal bleeding was the most common symptom found in 34(75.5%) cases followed by lower abdominal pain found in 30 (66.7%) patients, hyperemesis found in 14(31.1%) and dyspnea in 9 (20%). Thirty six (80%) patients received suction evacuation and 9 (20%) cases referred. Forty one (91.1%) patients were recovered but the rest 4 (8.9%) were lost during follow up. Conclusion: Low/middle socio-economic status, illiteracy and cases from rural areas had multiparous parity was highly effected by molar pregnancy disease and it can be controlled by early diagnose to take regular follow-up by using suction evacuation. Key words: Gestational trophoblastic disease (GTD), Molar pregnancy, Primiparous, Multiparous
Cerebrospinal Fluid Sterilization with Intrathecal Polymyxin in Addition to Parenteral Polymyxin in Nosocomial Acinetobacter Meningitis
Authors: Ishaque Sadia , Bari Ehsan , Shamim Muhammad Shahzad , Mahmood Syed Faisal
Published: August 2021

Background: For the last few decades there has been a substantial concern regarding the increasing prevalence of multidrug resistant (MDR) Acinetobacter species in hospitals. Aim: To determine the outcomes with intrathecal polymyxins therapy in patients with multidrug resistant Acinetobacter species nosocomial meningitis. Place and duration of study: This Retrospective study was conducted in the Department of Infectious Diseases, Aga Khan University Hospital, Karachi Pakistan between 2010 and 2014. Methodology: Twenty six patients who developed post neurosurgical MDR Acinetobacter nosocomial meningitis age above 18 were included, while those with polymicrobial meningitis, and those patients who only received intravenous polymyxins were excluded. The primary outcome is ability and time to sterilize the cerebrospinal fluid Results: The mean age was 42.9±11.5 years. Cerebrospinal fluid sterilization was observed in 24 patients in a median of 4 days. One patient made complete recovery, 16 patients recovered with neurological deficits and five patients expired. A trend of early cerebrospinal fluid sterilization was observed in patients with continuous intrathecal therapy. The time to cerebrospinal fluid sterilization is similar with intrathecal colistin or polymyxin. Conclusion: Intrathecal polymyxins are safe and efficacious in the treatment of multidrug resistant nosocomial Acinetobacter species meningitis. Keywords: Intrathecal, Polymyxins, Multidrug resistant, Acinetobacter species, Nosocomial, Meningitis
Effectiveness of Platelet Rich Plasma for the Management of Knee Osteoarthritis
Authors: Qamar Adnan , Mohsin Saima Naz , Siddiqui Uzma Nasim , Naz Sana , Danish Sana
Published: August 2021

Aim: To determine impact of platelet rich plasma therapy for the management of knee osteoarthritis. Study design: Prospective double-blinded, add –on randomized, placebo-controlled trial Place and duration of study: Department of Orthopedics, Shaikh Zayed Hospital Lahore from 1st January 2019 to 30th June 2019 Methodology: Fifty volunteer participants fulfilling inclusion criteria were enrolled. One hundred knees of patients were randomly allocated into two groups. Knees were assigned either of the two groups. Platelet rich plasma group which was assigned to receive 5ml of platelet rich plasma and normal saline (NS) group which was assigned to receive 5ml of NS labeled as control group. All patients given 3 successive intra-articular injections of 5 mL of autologous platelet rich plasma or 5ml of normal saline was given at weekly intervals. Patients were blinded and subjected to a standardized injection protocol and the intensity of pain was assessed on visual analog scale (VAS) for pain. Results: The VAS scores decreased from 50.9±14.7 at baseline assessment to 43.6±16.2 at 1-month follow-up after completion of therapy for PRP group (p<0.0203). The improvement was maintained from the end of the therapy to 3 and 6 months’ follow-up, as measure of VAS score as 30.54±11.8 and 20.2±8.6 respectively (p<0.0001). In normal saline group, there was very slight decrease in VAS score from baseline i.e. 49.8±19.5 to 48±22.7, 44±16.6, and 42±21.7 at 1, 3 and 6 months interval. Conclusion: Platelet rich plasma therapy can provide effective pain control up to 6 months post injection in knee osteoarthritis. Key words: Platelet rich plasma (PRP), Knee osteoarthritis (OA), Pain score
Outcomes of Redivac Drain in Primary Closure of Pilonidal Sinus
Authors: Karim Samina , Shah Ahmad , Nsar Ahmad Raza
Published: August 2021

Aim: To determine the effectiveness of redivac drain in primary closure of pilonidal sinus. Study Design: Comparative study Place and Duration of Study: Department of Surgery Unit-1, Sandeman Provincial Hospital Quetta from 1st January 2020 to 31st December 2020. Methods: Ninety patients of both genders were presented in this study. Patient’s details demographics age, sex and BMI were recorded after taking written consent. Patients were divided into two groups; group I and group II. Group I had 45 patients and underwent for redivac drain and group II was without redivac drain and had 45 patients. Complete follow up was done in duration of 6 months. Outcomes wound healing, infection of wound and recurrence of pilonidal sinus in both groups were observed. Results: Majority of the patients 66 (73.33%) were males and 24 (26.67%) were females. Mean age of the patients in group I was 28.52±6.88 years with mean BMI 24.16±7.33 kg/m2 and in group II mean age was 29.68±7.45 years with mean BMI 25.14±3.16 kg/m2. In group I 36 (80%) cases showed complete healing, partially healing was observed among 7 (15.55%) and 2 (4.44%) showed non-recurrence and in group II complete healing was among 26 (57.8%) patients, partially healing was found in 14 (31.11%) and non recurrence was among 5 (11.11%) patients. Rate of recurrence in group I was 3 (6.67%) less than that of group II (8.9%). Conclusion: The redivac was more effective as compared to primary closure of pilonidal sinus without redivac. Keywords: Redivac drain, Primary closure, Pilonidal sinus, Recurrence
Comparison of Outcomes between Elective Tracheostomy versus Emergency Tracheostomy
Authors: Khan Tarique , Rashid Abid , Samee Muhammad Awais , Ali Ahmed
Published: August 2021

Aim: To compare the frequency of early postoperative complications of elective tracheostomy and emergency tracheostomy. Study design: Comparative/observational study Place and duration of study: Department of ENT/Head & Neck Surgery, Mayo Hospital Lahore from 1st July 2012 to 31st December 2012. Methodology: One hundred patients of both genders undergoing tracheostomy were enrolled. All the patients were divided equally in two groups; Group A (elective) comprised 50 patients and group B (emergency) tracheostomies also comprised 50 patients. Early postoperative complications were examined and compare between both groups. Results: There were 28 (56%) and 22 (44%) males and females in group A with mean age 42.45±10.55 years while in group B 30 (60%) and 20 (40%) patients were male and females with mean age 43.06±9.84 years. Patients received emergency tracheostomy had high rate of postoperative complications as compared to elective tracheostomy (36% vs 16%). The difference was statistically significant(P<0.05). Conclusion: Early postoperative complications were high in patients underwent emergency tracheostomy as compared to elective tracheostomy. Keywords: Early complications, Elective tracheostomy, Emergency tracheostomy
Ameliorarting Action of Methylcaobalamin on Degenerated Cerebellar Molecular Cell Layer
Authors: Kohari Tazeen , Amjad Zaheer , Malick Zaffar
Published: August 2021

Background: Cerebellum the hindbrain is located in the posterior cranial fossa.The cerebellar cortex consists, of a gray matter and a white matter and the gray matter comprises of outer molecular layer, middle purkinje cell layer and inner most is the granule cell layer. The antimaniac drug lithium caused distortion to the outer molecular cell layer which was repaired and the damage was lessened by injecting the albino rats with Methylcobalamin. Aim: To observe and document the data of the restored thickness of molecular cell layer after Methylcobalamin administration. Methods: Eighteen albino rats were selected and were treated with lithium and Methylcobalamin for a period of 4 weeks. Results: The results showed regeneration and improved thickness of molecular cell layer stressing the need for educating our masses in dietary use of vitamin b12 and the consultants to prescribe Methylcobalamin in neuronal injuries. Conclusion: My study proved that the use of vitamin b12 is mandatory in strengthening and restoring the cerebellar molecular gray matter. Keywords: Cerebellar molecular cell layer,Degeneration, Regeneration
Anti-diabetic effect of Momordicacharantiaplant extract in streptozotocin induced diabetic mice
Authors: Sultan Nayyab , Hussain Zahid , Butt Sabahat Javaid , Butt Aqib Javaid
Published: August 2021

This study describes anti-hyperglycemic effect of Momordicacharantia extract commonly known as bitter melon. Random blood glucose levels were observed before and after plant extract administration. Powdered form of plant extract was used as an oral treatment. Diabetes was induced in animal (mice) models by using streptozotcin which is an artificial diabetes inducer. Maximum anti-hyperglycemic effect and blood glucose level reduction was observed in individual treatment of Momordicacharantiaextract (500mg/kg) which was 75% ± 1.3. This treatment was more effective as compared to Amaryl (3mg/kg) which shows effectiveness of 52% ± 2.4 and Glucophage (500mg/kg) which shows effectiveness of 29% ± 2.1. Results indicate that bitter melon contain anti-hyperglycemic proteins which are helpful in diabetes treatment without any toxic side effects. Still more research, experiments and testing needs to be perform. Keywords: Amaryl; Anti-hyperglycemic effect; Blood glucose levels; Body weight; Diabetes mellitus
Prevalence of dental caries among 3 to 11 years old children in Lahore
Authors: Rana Adeel Ijaz , Rana Saleem , Hassan Arooj Ul , Ahmad Fareed , Anwaar Ali , Riaz Marryam , Tariq Amina
Published: August 2021

Aim: To determine frequency of dental caries in mal-occluded teeth among children 3-11 years of age and compare dental caries in children with mal-occluded teeth Methodology: This cross sectional analytical study using purposive sampling technique was carried out at Dental hospital of Institute of dentistry, CMH Lahore Medical College, Lahore for 09 months After permission from institute of dentistry, CMH Lahore medical college and informed consent form participants or their parents/ guardian, they were included as male and female children aged 3-11 years that attended dental hospital of Institute of dentistry, CMH Lahore Medical College for dental treatment and had mal-occluded teeth. Children with mental, physical disabilities and whose parents/ guardian refused to take part were excluded. Dental caries in mal-occluded teeth of children was examined to report the frequency of dental caries. SPSS version 23 was used for analysis data. Results: Among the total of 330 patients included in the study, dental caries was observed in 260 (78.8%) of patients. Conclusion(s): Significant associations of dental caries were observed in terms of gender and age, monthly income, interventional urgency, and occupation and education status. Higher frequency of dental caries was observed in the upper middle and lower middle class groups. Keywords: Dental caries, Mal-occlusion, Pre-school children, Dental treatment
Association of maternal oral health with early childhood caries among rural areas of Punjab
Authors: Shakeel Roheen , Ishaque Aliya , Malik Aaqil , Qureshi Shahzad Waheed , Amin Gulrez , Baloch Faisal Ali , Tariq Amina
Published: August 2021

Aim: To explore the relationship between oral health status of mothers and caries prevalence of caries among their children in rural areas of Pakistan. Methodology: This crossectional study was conducted in 9 rural health centers of Punjab, Pakistan. Purposive convenient sampling was used to collect data. Sample size was 500 mothers with their children. Results: Socioeconomic status of family as well as the purpose for the last visit at dental hospital for the treatment of child were found positively linked with the dmfs of child. Sample of children at very low socioeconomic status (OR: 2.16; 95%CI: 1.36-2.98). Children who visited dental hospital with the reason of having dental problems (OR: 1.89; 95%CI: 1.25-2.59). Greater dmfs score was found among children with poor oral hygiene (OR: 1.98; 95%CI: 1.27-3.25). The education of mother was found to be negatively linked with dmfs score of child. Conclusion: The relationship between maternal and dental caries in children was clearly explained by socioeconomic status or dental behaviors of mother and child in terms of intake of sugar, oral hygiene and reason for last dental visit for child. Keywords: Maternal oral health, dmfs, childhood carries
Umbilical Artery and Middle Cerebral Artery and Cerebroplacental Ratio for Doppler Indices’ Reference Ranges
Authors: Sultana Arjuamnd , Anjum M. Nawaz , Asad Naveed , Haq Rizwan Ul , Shahid Taimoor , Sadaf Qudsia , Tariq Amina
Published: August 2021

Aim: To investigate the reference values of Doppler indices for umbilical artery and Middle Cerebral Artery as well as Cerebro-placental Ratio and specifically, to evaluate the quality of methodology used on which these reference values are grounded, with the help of already established quality standards for research design, statistical analysis as well as methods of results reporting. Methodology: The methodological quality of the full-text versions of eligible studies was assessed independently by the same reviewers and a medical statistician (E.S.U.). Disagreements were resolved by consensus or consultation with two other reviewers (A.T.P. and E.F.). Quality criteria for evaluation methodologies of the published articles was developed which was based on the already available research publication25,36,37. The methodology evaluation criteria was segregated into two levels, one is study design and the other one is statistics used as well as its reporting methods. Total no. of criteria of quality were 24 to be evaluated. Results: Generally, methodological quality score was parallel for the research articles designed to evaluate umbilical artery range (median 42%; range 13.8–63.8%). For the studies focusing on middle cerebral artery range showed a median of 48% with a Class interval of 22.1–72.1% whereas the median score of cerebroplacental ratio was 47.1% with a Class interval of 34.6–55.5%. Conclusion: Rigorous methodology of this review study is the major strength, which is consisted of a standard and well developed methodology of scoring the quality of studies according to their methodology selection as well as the statistical analysis and the level of its interpretation. Keywords: Umbilical artery, Middle Cerebral Artery, Cerebro-placental Ratio, Doppler indices
Assessment of Parental self-management of epileptic pediatric in terms of adherence of antiepileptic drugs
Authors: Iftikhar Danyal , Farooqi Rabia , Qureshi Shahzad Waheed , Tariq Amina , Ikram Amna Mehwish , Haidar Adeel
Published: August 2021

Aim: To assess the parental self-management of epileptic pediatric in terms of adherence of antiepileptic drugs Methodology: A descriptive cross-sectional study was conducted in Children Complex Hospital of Multan. Convenient sampling technique was used to collect the data from included population, care giver of epilepticus children. Reliability checked by Cronbach alpha which was 0.71. Data was analyzed in SPSS 25, to get percentage and frequency. Results: The majority of the responses were agree 86(81.9%) on the doctors/nurses fully explained seizures/epilepsy (diagnosis). 10(9.5%) were strongly agree that doctors and nurses fully explained seizures to them. What side effects they have to look for while they are in treatment, was reported in positive by 73(69.5%) participants. 63(60%) were agree about whom to contact for questions or problems. The results show that the 71(67.6%) were agree about the confidence with which they can in partnership with the health care team can manage side effects if occur. Conclusion: Parental self-management was found higher in epileptic pediatrics in Multan Keywords: Epileptic drugs, Pediatrics, self-management, nurses
Orthodontic Principles and Practice based Knowledge and Attitude among general dental practitioners
Authors: Ch. Shoaib Masood,Ch , Qamar Rehan , Amdad Fareeha , Hassan Muhammad , Tariq Amina
Published: August 2021

Background: This study was formulated for the comparative evaluation of the knowledge and attitude of the general dental practitioners and non-orthodontic specialties about the orthodontic treatment. Methodology: Data of this cross sectional study was collected from 100 general dentists between an age ranges of 30 to 50 years using simple random sampling from all over Lahore. Results: The percentage for the positive responses was 85.69% whereas the negative response rate was very low which was reported as 14.3%. This showed that dental practitioners in market are practicing orthodonticskills. The response rate of general practitioners was: 60.42% positive responses and 39.57% negative responses were obtained which showed that more than half of general dental practitioners have a positive attitude towards orthodontic treatment guidance to their patients with general complaints. Conclusion: The overall attitude of general dental practitioners is satisfactory towards orthodontic treatment in general patients. Moreover, dental practitioners in Pakistan are were well aware of the Skills used before, during and after the orthodontic treatment. Keywords: Clinical practice, Knowledge, Orthodontic treatment, Dental Practitioners
Protective Effect of Prunus Dulcis Against Acetylsalicylic Acid Injury on Gastric Parietal Cells
Authors: Abdullah M. Saad , Nahid Kishwar , Mushtaq Fareeha , Chughtai Aneeqa , Izhar Saba , Irshad Faiza , Khan M A. , Laique Talha
Published: August 2021

Background: Acetylsalicylic acid is in common clinical use but has the side effect of causing gastric mucosal erosions and selective injury to parietal cells. Aim: To explore if prior treatment with Prunus dulcis (almond) had a protective effect against acetylsalicylic acid induced injury. Study design: Experimental study. Methodology: Albino mice weighing 30 to 40 grams were given two drops of almond oil without peel and 300 mg of finely ground whole almond kernel by oral gavage for sixty days followed by 400 mg/kg body weight of acetylsalicylic acid orally. Gastric mucosal damage was observed and recorded as ulcer index. The number of parietal cells/ sq. micrometer and area of parietal cells were observed and recorded under microscope in formalin fixed H and E stained sections. Data analyzed by SPSS 22.0v. Results: Mucosal damage, distortion of gastric glands and damage to parietal cells was pronounced in the positive control animals. The number of surviving parietal cells after acetylsalicylic acid insult in animals given almond oil was significantly higher when compared with positive control animals (p<0.001) and even better in animals receiving whole ground almond kernel. The area of parietal cells was also similarly larger in the treated animals. Conclusion: This study concluded Prunus dulcis offers protection against acute gastric mucosal injury and damage to the gastric parietal cells caused by acetylsalicylic acid in mice. Keywords: Prunus Dulcis, Parietal Cells, Gastric Erosions and Acetylsalicylic Acid.
Interrelationship of Electrolyte and Vitamins Profile in Patients Experiencing Tumor Lysis Syndrome
Authors: Mastoor Khadija , Suhail Bushra , Inam Asma , Azam Nada , Amjad Maria , Bashir Fareeha
Published: August 2021

Background:Tumor lysis syndrome is a metabolic derangement which is seen in patients with malignancy and receiving drugs for cancer treatment. It can arise in children or older cancer patients and is considered life threatening. Anticancer drug therapy is most commonly used method to treat cancer. Aim: To investigate the role of electrolytes and vitamins (A, C and E) in cancer patients suffering from tumor lysis syndrome during anticancer therapy. Study design: Prospective clinical study Methods: The study enrolled fifty diagnosed patients of Tumor lysis syndrome.Informed consent was taken from patients.Twenty patients, clinically healthy, age and sex-matched were selected as a control in the present study. 5cc blood was withdrawn from enrolled cases. The obtained samples were centrifuged at the speed of 4000-5000rpm for 10-15 minutes to obtain serum. The levels of Electrolytes (Na+, K+), and Vitamins A, C, E were estimated. Results: Study showed elevated serum levels of sodium (Na+) (28.26) in comparison withcontrol normal persons (21.26) and this is significant statistically (0.02<0.05). Serum Potassium levels among Tumor lysis syndrome (TLS) cases was (13.26) as observed in normal controlled persons (14.26) and results were significant statistically (0.03<0.05). Vitamin A level in Tumor lysis syndrome(TLS) cases decreased outstandingly (102.20) in contrast to normal control study persons.(188.26) and this is significant statistically (0.026<0.05). The values for Vitamin E in Tumor lysis syndrome cases was (4.26) and in controlled normal individuals (7.26) and proved significant statistically (0.015<0.05). Conclusion: Present study showed inverse relationship between Vitamins and electrolytes in TLS. Increased level of electrolyte imbalances and decreased vitamin levels is the reason responsible for the development of tumor lysis syndrome. Keywords: TLS, Vit A, Vit C, Vit E, Na+,K+