bluuebunny/crossref_metadata_2025 huggingface dataset:
Promise and paradox: A critical sociohydrological perspective on small-scale managed aquifer recharge
Authors: Basel Britt , Hoogesteger Jaime , Hellegers Petra
Published: November 2022

Small-scale managed aquifer recharge (MAR) has significant potential as a bottom-up, community-based adaptation solution for increasing local groundwater availability and reducing the experience of drought for small-holder agriculturalists and rural populations. Using a suite of low-tech and low-cost techniques, small-scale MAR increases the infiltration of surface water runoff to replenish groundwater and deliver a suite of societal and ecosystem benefits. While the technique is hydrologically promising, populations may not act, implementation may not be permitted, interventions may not be effective for the population in question, or unexpected consequences (paradoxes) may result. For small-scale MAR to effectively reduce the experience of drought, it is imperative to unravel how such interventions play out within the complexity of the sociohydrological system in which they are implemented. Building on previous conceptualizations of the sociohydrological system, we apply the lens of political ecology to conceptualize the interplay between biophysical, climate, and social systems. Additionally, we explore considerations, feedbacks, and potential paradoxes in the uptake, implementation, and effectiveness of small-scale MAR interventions. We show that within the parameters of climate trends, small-scale MAR may serve to increase the functionality of ecosystems and reduce the impact of climate extremes, while protecting livelihoods and supporting society. In a positive feedback loop, small-scale MAR may both reduce the likelihood of experiencing drought while simultaneously increasing the ability and likelihood of the population to cope with or further avoid drought. Paradoxes and negative feedback processes, however, must be avoided. Specific factors, and how such factors interplay, will be different in each context where small-scale MAR is implemented. Conceptualizing the sociohydrological system in which small-scale MAR is implemented, including explicitly accounting for climate trends and using a power-sensitive approach, allows us to avoid overestimating or oversimplifying small-scale MAR as a solution, while supporting practical and effective implementation.
Effects of Uplift Resistance on Continuous-Pipe-Foundation of Single-Span Plastic Greenhouse by Steel Plate Pipe Connector
Authors: Kim Myeonghwan
Published: November 2022

The single-span plastic greenhouses are affected by strong winds which generate uplift resistance causing the bending of members, damage to protective films, and damage to crops. This study performed a field test using the static axial tensile load method to present basic data to prevent damage to a single-span plastic greenhouse. Three representative areas were selected, and the effects of pipe connectors, rafter spacing, and embedding depth were tested. In the field test results, it was found to be greatly affected by the pipe connector. The pull-out resistance at the site fixed by welding instead of the pipe connector was measured as 4.5 times the sliding resistance standard value of the Rural Development Administration. In other sites, the measurement was below the standard value of the sliding resistance of the pipe connector. It was confirmed that the uplift resistance is determined by the sliding resistance of the pipe connector, the rafters, and the crossbar pipe. Therefore, it seems possible to increase the uplift resistance of a single-span plastic greenhouses continuous foundation through the reinforcement of the pipe connector. The field test results can be utilized as basic data for the reinforcement of the commercialization of single-span plastic greenhouses and new standards.
Tribological Study of Simply and Duplex-Coated CrN-X42Cr13 Tribosystems under Dry Sliding Wear and Progressive Loading Scratching
Authors: Maros Maria Berkes , Siddiqui Shiraz Ahmed
Published: November 2022

CrN coatings are widely used in the industry due to their excellent mechanical features and outstanding wear and corrosion resistance. Using scratch and ball-on-disk wear tests, the current study deals with the tribological characterisation of CrN coatings deposited onto an X42Cr13 plastic mould tool steel. Two surface conditions of the secondary-hardened substrate are compared—the plasma nitrided (duplex treated) and the un-nitrided (simply coated) states. The appropriate combination of secondary hardening providing the maximum toughness and the high-temperature nitriding of this high Cr steel is a great challenge due to the nitrogen-diffusion-inhibiting effect of Cr. The beneficial effect of the applied duplex treatment is proven by the 34% improvement of the adhesion strength and the 43% lower wear rate of the investigated duplex coatings. Detailed morphological analyses give insight into the characteristic damage mechanisms controlling the coating failure processes during scratching and wearing. For the simply CrN-coated sample, a new type of scratch damage mechanism, named “SAS-wings”, is identified, providing useful information in predicting the final failure of the coating. The tribological results obtained on tribosystems with the investigated high Cr steel/CrN constituents represent a novelty in the given field.
Synthesis and Characterization of Ceria- and Samaria-Based Powders and Solid Electrolytes as Promising Components of Solid Oxide Fuel Cells
Authors: Kalinina Marina V. , Dyuskina Daria A. , Arsent’ev Maxim Y. , Mjakin Sergey V. , Shilova Olga A.
Published: November 2022

Finely dispersed (CeO2)0.95(Sm2O3)0.05, (CeO2)0.90(Sm2O3)0.10 and (CeO2)0.80(Sm2O3)0.20 mesoporous powders with a specific pore volume of 0.080–0.092 cm3/g and a specific surface of 50–83 m2/g are synthesized by the co-precipitation of cerium and samarium hydroxides from the corresponding nitrate solutions. The prepared powders are used to obtain ceramic nanomaterials with a fluorite-like cubic crystal lattice with a coherent scattering region (CSR) of about 65–69 nm (1300 °C). The study of physicochemical and electrophysical properties of the prepared ceramics revealed the obtained materials featuring an open porosity of 2–6% and a predominantly ionic type of electric conductivity (ion transport numbers ti = 0.85–0.73 in the temperature range 300–700 °C). The conductivity in solid solutions proceeds via a vacancy mechanism with σ700 °C= 3.3·10−2 S/cm. The synthesized ceramic materials are shown to be promising as solid oxide electrolytes in medium temperature fuel cells.
The Effects on Neighborhood Environments during Lockdowns: Being Comfortable in Residences
Authors: Gul Yasmeen , Jokhio Gul Ahmed , Sultan Zahid , Smith John Alexander , Nizam Wan Saiful , Moeinaddini Mehdi , Hafiz Dalia
Published: November 2022

Cities around the world have been hit by the COVID-19 crisis. The worst consequences of the pandemic are closely related to urban areas. Many studies investigated the impact of COVID-19 on people but there are few studies that have investigated the satisfaction level of university students during the COVID-19 lockdown at the neighborhood level. Therefore, the aim of this study is to investigate the satisfaction of university students at the neighborhood level during the COVID-19 lockdown and investigate the experience of online education during that period—if they received any. An online survey was conducted involving university students of different countries, and a total of 427 responses (n = 427) were received and analyzed using the CHAID model. Results show that comfort at residences during the COVID-19 lockdown was affected by the neighborhood environment (viz., greenery, pleasant views, independent housing with gardening facilities), transportation (i.e., saving 1–2 commuting hours on a daily basis and safety from traffic hazards), and the provision of online education (i.e., effectiveness, such as traditional methods of education and the opportunity to connect with field experts). Thus, it can be concluded that providing green neighborhoods, detached or terraced houses (townhouses) with visual connection, and gardening facilities for the residents should be encouraged in the future because these types of neighborhoods are not only comfortable in ordinary situations but also provide comfort during critical periods such as COVID-19 lockdowns. It can also be concluded that a hybrid style of education should be encouraged for universities, as it can save travel time, provide safety from traffic, and provide more opportunities to become connected with international experts through online guest lectures, seminars, and workshops.
Performance Comparison and Light Reflectance of Al, Cu, and Fe Metals in Direct Contact Flat Solar Heating Systems
Authors: AlShamaileh Ehab , Moosa Iessa Sabbe , Al-Fayyad Heba , Lahlouh Bashar , Kazem Hussein A. , Abu-Afifeh Qusay , Al-Saqarat Bety S. , Esaifan Muayad , Hamadneh Imad
Published: November 2022

The Sun is a huge and clean energy source that must be relied upon to reduce greenhouse gases and promote the renewable and sustainable energy transition. In this paper, the testing of Al, Cu, and Fe metals with different thicknesses, both bare and painted matte black, was investigated for solar water heating systems. The used technique was a direct contact flat solar heating system (DCFSHS). Many experiments were run to assess this system in terms of metals’ thicknesses and their thermal conductivities as well. Thicknesses of around 0.35 mm and 1 mm of Cu gave almost similar feedback. Maximum temperatures in the range of 93–97 °C were achieved during the autumn season in Amman, Jordan, while it was approximately 80 °C in winter. It has been confirmed that high water temperatures can be obtained in all used metals, regardless of their thermal conductivities. It was also found that a white color of the solar heater case inner wall leads to an increase in water temperature of approximately 4 °C in comparison to a black color. Furthermore, a light reflectance % test in the wavelength range of 240–840 nm for the studied metals, with both bare and black-painted surfaces, gave a superb result that was in line with the obtained results of the DCFSHS. Our innovative system design for solar water heating is due to improvements in many aspects, such as design, production costs, environment, and weight.
Modernized Planning of Smart Grid Based on Distributed Power Generations and Energy Storage Systems Using Soft Computing Methods
Authors: Rajagopalan Arul , Swaminathan Dhivya , Alharbi Meshal , Sengan Sudhakar , Montoya Oscar , El-Shafai Walid , Fouda Mostafa , Aly Moustafa
Published: November 2022

The modest objective is to check the integrated effect of energy storage systems (ESSs) and distributed generations (DGs) and compare the optimization of the size and location of ESS and DG to explore its challenges for smart grids (SGs) modernization. The research enlisted different algorithms for cost-effectiveness, security, voltage control, and less power losses. From this perspective, optimization of the distribution network’s energy storage and capacity are being performed using a variety of methods, including the particle swarm, ant-lion optimization, genetic, and flower pollination algorithms. The experimental outcomes demonstrate the effectiveness of these techniques in lowering distribution network operating costs and controlling system load fluctuations. The efficiency and dependability of the distribution network (DN) are both maximized by these strategies.
Energy Recovery from Natural Gas Pressure Reduction Stations with the Use of Turboexpanders: Static and Dynamic Simulations
Authors: Bielka Paweł , Kuczyński Szymon
Published: November 2022

The application of expansion turbines at natural gas pressure reduction stations (PRS) is considered in order to recover energy contained in the natural gas. This energy is irretrievably lost at the reduction stations which use the traditional pressure reducer. Expanders allow for the electricity production for PRS own needs and for resale. The paper presents an analysis of the possibility of using turboexpanders at PRS in Poland. Authors performed static simulations for the assumed data sets and dynamic simulations for annual data from selected representative natural gas reduction and measurement stations. Energy balances are presented for the discussed scenarios that compare the energy requirements of natural gas pressure reduction stations which use a classic pressure reducer or turboexpander (TE). Using static simulations, authors investigated whether the use of a turboexpander is economically justified for the case if it is used only to supply the reduction station with electricity. Dynamic analyses were carried out using real data. In addition, static analyses were performed for a natural gas reduction and measurement station using a PEM fuel cell for the production of electricity in a combined gas heating system. At higher inlet temperatures and pressures, the expansion process was more economical due to the lower heat power requirement and the greater amount of produced electricity. The PRS with the turboexpander compared to the PRS with the reducer required the supply of thermal energy which did not allow the PRS to lower operating costs for the assumed prices of heat and electricity. The reduction system with the PEM fuel cell in the combined heating system positively achieved lower operating costs of the PRS (without taking into account the investment costs). Total annual costs for PRS with a reducer was PLN 1,593,167.04, and for PRS with TE + PEM PLN 1,430,595.60—the difference was PLN 108,571.44 in favor of the arrangement with TE and PEM. The payback time should be investigated, although the use of such a system gives the impression of oversizing. An increase in the electricity purchase price and a decrease in the natural gas purchase price may contribute to the investment in the future.
The Impact of the COVID-19 Pandemic and Energy Crisis on CSR Policy in Transport Industry in Poland
Authors: Stanislawska Marta
Published: November 2022

The main objective of this research, directly related to the introduction of the COVID-19 pandemic, is to answer the question: has the epidemiological situation and energy crisis affected the CSR policy of transport industry companies and the forms of its implementation? This research aims to answer whether the social objective set out in the CRS policy, implemented by the studied entities, conflicts with commercial purposes, whether the implementation of CRS is profitable for these entities, and in which areas of activity it manifests itself. The aim is to investigate why the studied entities engage in CSR? The following research methods were applied: an economic and legal analysis of CRS principles and activity reports. The study focused on the activities of enterprises pursuing their business objectives and, at the same time, their socio-cultural mission. The CSR policies for 2019–2021, which surveyed transport industry companies operating in Poland, are analyzed. Empirical findings show that companies are responsive to the CSR concept and those considering international standards.
Study on the Law and Risk of Spontaneous Combustion of Residual Coal during Water Drainage in Goaf
Authors: Zhao Xiaohao , Yang Yongliang , Wang Yonghui , Li Purui , Zhang Yifan , Shen Chang
Published: November 2022

Water–gas displacement occurring during the drainage of water-soaked goafs facilitates the oxidation of water-soaked coal. The characteristics of oxygen migration and the oxidation and spontaneous combustion (SC) of soaked residual coal during goaf drainage were explored through laboratory research, water drainage simulation and on-site measurement. The results reveal that compared with raw coal samples, the amount and rate of gas products of water-soaked coal samples are higher in the heating oxidation process, demonstrating a strengthened spontaneous combustion (SC) propensity. Its cross-point temperature falls and the apparent activation energy decreases by 1.43–8.75%, that is, the soaked coal sample is easier to spontaneously combust during the drainage of water-soaked goafs. Through simulation, it is found that after water is drained, air leakage in the goaf is significantly intensified, and the pressure difference inside and outside the goaf reaches 498 Pa. By taking the air inlet roadway as the air leakage point for fitting, it is found that the oxygen concentration in the air leakage range increases to 18% during water drainage. The simulation results are basically consistent with the on-site measurement. The on-site monitoring result shows that during water drainage of 7225 goaf in Qinan Coal Mine, water-immersed coal is more prone to spontaneous combustion, and air leakage leads to low-temperature oxidation of water-immersed coal, which increases the on-site temperature rapidly and increases the risk of spontaneous combustion in the goaf. With respect to water drainage in the goaf, an optimization measure of fixed-point and quantitative nitrogen injection during water drainage was put forward on site.
Insights into the Thermal Performance of Underground High Voltage Electricity Transmission Lines through Thermo-Hydraulic Modelling
Authors: Liu Kui , Zagorščak Renato , Sandford Richard J. , Cwikowski Oliver N. , Yanushkevich Alexander , Thomas Hywel R.
Published: November 2022

In this paper, a flexible numerical framework to provide thermal performance assessment for the underground buried cables, considering different geological and meteorological conditions, has been presented. Underground cables tend to retain the heat produced in the conductor, so complex coupled thermo-hydraulic response of the porous medium surrounding the cables needs to be assessed to prevent cable overheating and the associated reduction in cable capacity for carrying current. Applying a coupled thermo-hydraulic model within the developed numerical framework to conduct a health assessment on a subset of National Grid Electricity Transmission’s underground cables, this study provides novel insights into the thermal behaviour of buried circuits. The results indicate that backfill and surrounding native soil have the dominant effect on the thermal behaviour of cables, while the amount of precipitation and ambient temperature were found to have less impact on cable’s thermal behaviour. The findings strongly infer that the nature of the overloading which is undertaken in practice would have no ongoing negative impact, suggesting that more frequent or longer duration overloading regimes could be tolerated. Overall, this study demonstrates how the developed numerical framework could be harnessed to allow safe rating adjustments of buried transmission circuits.
Impact on Thermal Energy Needs Caused by the Use of Different Solar Irradiance Decomposition and Transposition Models: Application of EN ISO 52016-1 and EN ISO 52010-1 Standards for Five European Cities
Authors: Summa Serena , Remia Giada , Sebastianelli Ambra , Coccia Gianluca , Di Perna Costanzo
Published: November 2022

To solve the series of heat balances that EN ISO 52016-1 uses to simulate the dynamic hourly energy requirements of a building, detailed climatic data are required as input. Differently from air temperatures, relative humidity and wind speed, which are easily measurable and available in databases, the direct and diffuse solar irradiances incident on the different inclined and oriented surfaces, which are fundamental for the evaluation of solar gains, must be estimated using one of the many regression models available in the literature. Therefore, in this work, the energy needs of buildings were evaluated with the simplified hourly dynamic method of EN ISO 52016-1 by varying the solar irradiance sets on inclined and oriented surfaces obtained from EN ISO 52010-1 and three other pairs of solar irradiance separation and transposition models. Five European locations and two different window solar transmission coefficients (ggl) were analysed. The results showed that on average, for the heating period and for both ggl, the use of the different methods causes an average error on the calculation of the annual demand of less or slightly more than 5%; while for the cooling period, the average error on the calculation of the annual demand is 16.4% for the case study with ggl = 0.28 and 25.1% for the case study with ggl = 0.63. On the other hand, analysing the root-mean-square-error of the hourly data, using the model contained in TRNSYS as a benchmark, for most of the cases, when varying window orientations, cities and ggl, the model that diverges furthest from the others is that contained in EN ISO 52010-1.
Technical and Economic Assessment of Battery Storage and Vehicle-to-Grid Systems in Building Microgrids
Authors: Correia Alexandre F. M. , Moura Pedro , de Almeida Aníbal T.
Published: November 2022

In an electrical microgrid, distributed renewable generation is one of the main tools used to achieve energy sustainability, cost efficiency and autonomy from the grid. However, reliance on intermittent power sources will lead to a mismatch between generation and demand, causing problems for microgrid management. Flexibility is key to reducing the mismatch and providing a stable operation. In such a context, demand response and energy storage systems are the main factors that contribute to flexibility in a microgrid. This paper provides an assessment of the technical and economic impacts of a microgrid at the building level, considering photovoltaic generation, battery energy storage and the use of electric vehicles in a vehicle-to-building system. The main novel contributions of this work are the quantification of system efficiencies and the provision of insights into the design and implementation of microgrids using real on-site data. Several tests were conducted using real on-site data to calculate the overall efficiencies of the different assets during their operation. An economic assessment was carried out to evaluate the potential benefits of coordinating battery storage with a vehicle-to-building system regarding the flexibility and cost-efficient operation of the microgrid. The results show that these two systems effectively increase the levels of self-consumption and available flexibility, but the usefulness of private electric vehicles in public buildings is constrained by the schedules and parking times of the users. Furthermore, economic benefits are highly dependent on the variability of tariffs and the costs of energy storage systems and their degradation, as well as the efficiency of the equipment used in the conversion chain.
Performance Assessment of a Novel Solar and Biomass-Based Multi-Generation System Equipped with Nanofluid-Based Compound Parabolic Collectors
Authors: Ibrahim Alla Ali , Kayfeci Muhammet , Georgiev Aleksandar G. , Dolgun Gülşah Karaca , Keçebaş Ali
Published: November 2022

The current paper proposes a novel multi-generation system, integrated with compound parabolic collectors and a biomass combustor. In addition to analyzing the comprehensive system in a steady state, the feasibility of using nanofluids as heat transfer fluids in the solar cycle and their effect on the overall performance of the system was studied. The multi-generation system is generally designed for generating electricity, cooling, freshwater, drying, hot water, and hydrogen, with the help of six subsystems. These include a double stage refrigeration system, an organic Rankine cycle, a steam Rankine cycle, a dryer, a proton exchange membrane electrolyzer, and a multistage flash distillation system. Two types of nanoparticles (graphene, silver), which have various high-quality properties when used within ethylene glycol, were chosen as absorbing fluids in the solar cycle. The performance parameters of the base case thermodynamic analysis and some of the variable parameters were calculated, and their effect on system performance was determined. According to the results, a spike in solar irradiation, ambient temperature, output temperature of biomass combustor and nanofluids’ concentration positively affected the overall system performance. The results also clearly showed an improvement in system performance when using nanofluids as working fluids in solar collectors.
On Critical Fractional p&q-Laplacian Equations with Potential Vanishing at Infinity
Authors: Wang Li , Zhong Qiaocheng , Niu Rui
Published: November 2022

The goal of the present paper is to investigate the critical Schrödinger-type fractional p&q-Laplacian problems. By employing the mountain pass theorem, we prove the existence and asymptotic property of nontrivial solutions for the problem.
Letting Go, Coming Out, and Working Through: Queer Frozen
Authors: Cocks Neil Hayward
Published: November 2022

This article builds on an already established understanding of Disney’s Frozen as a queer text. Following Judith Butler, however, it works against a notion of ‘queer’ that is locatable in the intrinsic truth of plot, imagery, and character, and removed from questions of performance and narration. In taking this approach, and in keeping with the focus of this Special Edition of Humanities, the article undertakes an extensive, fine-grained reading of ‘Let it Go’, the stand-out song from the first Frozen film. Rather than argue for or against the idea that ‘Let it Go’ is a Coming Out song, issues of textual perspective and textual difference are foregrounded in a way that challenges claims to the stability of identity. The pressing question, for this article, is not whether the lead character of Frozen truly is ‘out’, but the possibility of fixing identity in this way, the precise nature of the reversals and antagonisms that being ‘out’ and ‘letting it go’ require in this particular text, and how such determinations might impact on a wider understanding of ‘queer’.
Developmental Screening Tools Used with First Nations Populations: A Systematic Review
Authors: Cibralic Sara , Hawker Patrick , Khan Feroza , Mendoza Diaz Antonio , Woolfenden Susan , Murphy Elisabeth , Deering April , Schnelle Clare , Townsend Sharnee , Doyle Kerrie , Eapen Valsamma
Published: November 2022

Developmental surveillance and screening is recommended for all children under five years of age, especially for those from at-risk populations such as First Nations children. No review to date has, however, evaluated the use of developmental screening tools with First Nations children. This review aimed to examine and synthesise the literature on developmental screening tools developed for, or used with, First Nations populations children aged five years or younger. A PRISMA-compliant systematic review was performed in the PsychInfo, PubMed, and Embase databases. Additional searches were also undertaken. In total 444 articles were identified and 13 were included in the final review. Findings indicated that several developmental screening tools have been administered with First Nations children. Most tools, however, have only been evaluated in one study. Results also found that no studies evaluated actions taken following positive screening results. More research evaluating the accuracy, acceptability, and feasibility of using developmental screeners with First Nations children is required before widespread implementation of developmental screening in clinical settings with First Nations children is recommended.
Assessing the Efficiency and Productivity of the Hospital Clinics on the Island of Rhodes during the COVID-19 Pandemic
Authors: Androutsou Lorena , Kokkinos Michail , Latsou Dimitra , Geitona Mary
Published: November 2022

(1) Background: The aim was to measure the efficiency and productivity of 15 specialty clinics during the COVID-19 pandemic period 2020–2021 in the General Hospital of Rhodes. (2) Methods: An input-oriented data envelopment analysis and the Malmquist productivity index are used. Labor and capital were used as inputs, and in-patient discharges and days were used as outputs. (3) Results: Five out of the seven clinics in the pathology sector appeared fully efficient with an optimal productivity, and the rest showed progress in 2021. In 2020 the COVID-19 pathology clinic appeared to be inefficient and less productive, while in 2021, it showed a positive performance change. The surgical sector showed very high efficiency rates or even reached an optimal efficiency in both years. The productivity measurement, in most of the surgical clinics, was satisfactory to very high. In 2020 the COVID-19 surgical clinic appeared to be more efficient and productive than in 2021 when its performance declined. (4) Conclusions: The hospital responded to the pressure during the pandemic, by increasing its efficiency and productivity from 2020 to 2021. This was due to the accomplishment of the appropriate organizational changes in the infrastructure, human resources, and technology. The efficiency and productivity assessments should be incorporated in the hospitals’ decision making.
Exploring the Nonlinear Relationship between Renewable Energy Consumption and Economic Growth in the Context of Global Climate Change
Authors: Feng Yuting , Zhao Tong
Published: November 2022

In recent years, the impact of global climate change has increasingly revealed that energy transformation has become an indispensable part of achieving carbon neutrality. Thus, the relationship between energy transformation and economic growth has become the focus of academic attention. This study examines energy transition issues by using the panel threshold method. It explores the nonlinear impact of renewable energy consumption on economic growth, identifies various factors that lead to this nonlinear impact, and verifies its threshold effect. A comprehensive analysis reveals the following. (1) Overall, renewable energy consumption inhibits real gross domestic product (GDP) growth, but, in the long run, the negative impact becomes positive. (2) The threshold effect of energy consumption intensity (EI) is significant, with a threshold value of approximately 3.213. This means that when EI ≤ 3.213, renewable energy consumption promotes economic growth. However, EI > 3.213 indicates that this impact is significantly negative, which means that advancing the energy transition at this time may occur at the expense of real GDP growth. (3) There is also a significant threshold effect in energy transformation, with a threshold value of approximately 6.456. Similarly, when energy consumption transition (ET) ≤ 6.456, renewable energy consumption dampens real economic growth, and the economic cost of promoting renewable energy consumption is greater at this time. Alternatively, when ET > 6.456, this impact is significant at the 1 percent level and significantly positive. (4) There is also a significant threshold effect for emerging technologies, with a threshold value of approximately 1.367. When ET ≤ 1.367, renewable energy consumption dampens real economic growth, and the economic cost of promoting renewable energy consumption is greater. When ET > 1.367, the impact is significantly positive at the 1% level. To promote the positive development of economic growth, climate change, and energy transition, the nonlinear relationship studied in this paper can fill the gaps in existing research in theory and provide a theoretical basis for the government to adopt different policies at different stages of the energy transition to lay the foundation for improving global climate change in practice.
Knowledge, Attitude, Risk Perception, and Health-Related Adaptive Behavior of Primary School Children towards Climate Change: A Cross-Sectional Study in China
Authors: Wang Yu , Zhang Xinhang , Li Yonghong , Liu Yanxiang , Sun Bo , Wang Yan , Zhou Zhirong , Zheng Lei , Zhang Linxin , Yao Xiaoyuan , Cheng Yibin
Published: November 2022

Background: Children are disproportionately affected by climate change while evidence regarding their adaptive behavior and relevant influencing factors is limited. Objectives: We attempted to investigate health-related adaptive behavior towards climate change for primary school children in China and explore potential influencing factors. Methods: We conducted a survey of 8322 primary school children in 12 cities across China. Knowledge, attitude, risk perception, and adaptive behavior scores for children were collected using a designed questionnaire. Weather exposures of cities were collected from 2014 to 2018. We applied a multiple linear regression and mixed-effect regression to assess the influencing factors of adaptive behavior. We also used the structural equation model (SEM) to validate the theoretical framework of adaptive behavior. Results: Most children (76.1%) were aware of climate change. They mainly get information from television, smartphones, and the Internet. A 1 score increase in knowledge, attitude, and risk perception was associated with 0.210, 0.386, and 0.160 increase in adaptive behavior scores, respectively. Females and children having air conditioners or heating systems at home were positively associated with adaptive behavior. Exposure to cold and rainstorms increased the adaptive behavior scores, while heat exposure had the opposite effects. The SEM showed that knowledge was positively associated with attitude and risk perception. Knowledge, attitude, and risk perception corresponded to 31.6%, 22.8%, and 26.1% changes of adaptive behavior, respectively. Conclusion: Most primary school children in China were aware of climate change. Knowledge, attitude, risk perception, cold, and rainstorm exposure were positively associated with health-related adaptive behavior towards climate change.
The Role of Reversible Phosphorylation of Drosophila Rhodopsin
Authors: Smylla Thomas K. , Wagner Krystina , Huber Armin
Published: November 2022

Vertebrate and fly rhodopsins are prototypical GPCRs that have served for a long time as model systems for understanding GPCR signaling. Although all rhodopsins seem to become phosphorylated at their C-terminal region following activation by light, the role of this phosphorylation is not uniform. Two major functions of rhodopsin phosphorylation have been described: (1) inactivation of the activated rhodopsin either directly or by facilitating binding of arrestins in order to shut down the visual signaling cascade and thus eventually enabling a high-temporal resolution of the visual system. (2) Facilitating endocytosis of activated receptors via arrestin binding that in turn recruits clathrin to the membrane for clathrin-mediated endocytosis. In vertebrate rhodopsins the shutdown of the signaling cascade may be the main function of rhodopsin phosphorylation, as phosphorylation alone already quenches transducin activation and, in addition, strongly enhances arrestin binding. In the Drosophila visual system rhodopsin phosphorylation is not needed for receptor inactivation. Its role here may rather lie in the recruitment of arrestin 1 and subsequent endocytosis of the activated receptor. In this review, we summarize investigations of fly rhodopsin phosphorylation spanning four decades and contextualize them with regard to the most recent insights from vertebrate phosphorylation barcode theory.
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy
Authors: Zhang Xinyi , Liang Peiyu , Zhang Yahui , Wu Yifan , Song Yinghao , Wang Xueyang , Chen Taoxiang , Peng Biwen , Liu Wanhong , Yin Jun , Han Song , He Xiaohua
Published: November 2022

Epilepsy is a chronic neurological disorder whose pathophysiology relates to inflammation. The potassium channel Kv1.3 in microglia has been reported as a promising therapeutic target in neurological diseases in which neuroinflammation is involved, such as multiple sclerosis (MS), Alzheimer’s disease (AD), Parkinson’s disease (PD), and middle cerebral artery occlusion/reperfusion (MCAO/R). Currently, little is known about the relationship between Kv1.3 and epilepsy. In this study, we found that Kv1.3 was upregulated in microglia in the KA-induced mouse epilepsy model. Importantly, blocking Kv1.3 with its specific small-molecule blocker 5-(4-phenoxybutoxy)psoralen (PAP-1) reduced seizure severity, prolonged seizure latency, and decreased neuronal loss. Mechanistically, we further confirmed that blockade of Kv1.3 suppressed proinflammatory microglial activation and reduced proinflammatory cytokine production by inhibiting the Ca2+/NF-κB signaling pathway. These results shed light on the critical function of microglial Kv1.3 in epilepsy and provided a potential therapeutic target.
An Overview of the Molecular Cues and Their Intracellular Signaling Shared by Cancer and the Nervous System: From Neurotransmitters to Synaptic Proteins, Anatomy of an All-Inclusive Cooperation
Authors: Arese Marco , Bussolino Federico , Pergolizzi Margherita , Bizzozero Laura
Published: November 2022

We propose an overview of the molecular cues and their intracellular signaling involved in the crosstalk between cancer and the nervous system. While “cancer neuroscience” as a field is still in its infancy, the relation between cancer and the nervous system has been known for a long time, and a huge body of experimental data provides evidence that tumor–nervous system connections are widespread. They encompass different mechanisms at different tumor progression steps, are multifaceted, and display some intriguing analogies with the nervous system’s physiological processes. Overall, we can say that many of the paradigmatic “hallmarks of cancer” depicted by Weinberg and Hanahan are affected by the nervous system in a variety of manners.
New Advances in Iron Metabolism, Ferritin and Hepcidin Research
Authors: Arosio Paolo
Published: November 2022

The interest in the regulation of iron metabolism has increased in recent years with the clarification of the mechanism by which hepcidin regulates systemic iron homeostasis and the discovery of ferritinophagy, the major mechanism of ferritin degradation, which plays a major role in intracellular iron homeostasis and ferroptosis [...]
Luminescence, Paramagnetic, and Electrochemical Properties of Copper Oxides-Decorated TiO2/Graphene Oxide Nanocomposites
Authors: Bala Daniela , Matei Iulia , Ionita Gabriela , Cosma Dragos-Viorel , Rosu Marcela-Corina , Stanca Maria , Gaidau Carmen , Baleanu Maria , Virgolici Marian , Stanculescu Ioana
Published: November 2022

The properties of newly synthesized Cu2O/CuO-decorated TiO2/graphene oxide (GO) nanocomposites (NC) were analyzed aiming to obtain insight into their photocatalytic behavior and their various applications, including water remediation, self-cleaning surfaces, antibacterial materials, and electrochemical sensors. The physico-chemical methods of research were photoluminescence (PL), electron paramagnetic resonance (EPR) spectroscopy, cyclic voltammetry (CV), and differential pulse voltammetry (DPV). The solid samples evidenced an EPR signal that can be attributed to the oxygen-vacancy defects and copper ions in correlation with PL results. Free radicals generated before and after UV-Vis irradiation of powders and aqueous dispersions of Cu2O/CuO-decorated TiO2/GO nanocomposites were studied by EPR spectroscopy using two spin traps, DMPO (5,5-dimethyl-1-pyrroline-N-oxide) and CPH (1-hydroxy-3-carboxy-2,2,5,5-tetramethylpyrrolidine), to highlight the formation of hydroxyl and superoxide reactive oxygen species, respectively. The electrochemical characterization of the NC modified carbon-paste electrodes (CPE) was carried out by CV and DPV. As such, modified carbon-paste electrodes were prepared by mixing carbon paste with copper oxides-decorated TiO2/GO nanocomposites. We have shown that GO reduces the recombination process in TiO2 by immediate electron transfer from excited TiO2 to GO sheets. The results suggest that differences in the PL, respectively, EPR data and electrochemical behavior, are due to the different copper oxides and GO content, presenting new perspectives of materials functionalization.
Impairment of Vitamin D Nutritional Status and Metabolic Profile Are Associated with Worsening of Obesity According to the Edmonton Obesity Staging System
Authors: Cordeiro Adryana , Luna Mariana , Pereira Silvia Elaine , Saboya Carlos José , Ramalho Andrea
Published: November 2022

Obesity is associated with a higher risk of Vitamin D (VD) inadequacy and metabolic diseases. The Edmonton Obesity Staging System (EOSS) is an innovative tool for the evaluation of obesity that goes beyond body weight and considers clinic, functional and menta- health issues. This study aimed to evaluate the nutritional status of VD according to the stages of EOSS and its relationship with the metabolic profile. In the cross-sectional study, we evaluated anthropometric parameters, physical activity, blood pressure, biochemical and metabolic variables, and VD nutritional status. A total of 226 individuals were categorized using EOSS: 1.3%, 22.1%, 62.9%, and 13.7% were in stages 0, 1, 2 and 3, respectively. Regarding the metabolic changes and comorbidities, insulin resistance and hyperuricemia were diagnosed in some individuals in EOSS 1, 2, and 3. EOSS 2 and 3 presented a significant relative-risk for the development of arterial hypertension, metabolic syndrome, and liver disease, compared with EOSS 0. In all stages, there were observed means of 25(OH)D serum concentrations below 30 ng/mL (EOSS 0 24.9 ± 3.3 ng/mL; EOSS 3 15.9 ± 5.4 ng/mL; p = 0.031), and 25(OH)D deficiency was present in all stages. Individuals with obesity classified in more advanced stages of EOSS had lower serum concentrations of 25(OH)D and a worse metabolic profile.
Heterogeneity of Patient-Derived Acute Myeloid Leukemia Cells Subjected to SYK In Vitro Inhibition
Authors: Brattås Marte Karen , Hemsing Anette Lodvir , Rye Kristin Paulsen , Hatfield Kimberley Joanne , Reikvam Håkon
Published: November 2022

Acute myeloid leukemia (AML) is an aggressive hematological malignancy with a dismal prognosis. The cytoplasmic spleen tyrosine kinase (SYK) is highly expressed by hematopoietic cells and has emerged as a potential therapeutic target. In this study, we evaluated the in vitro antileukemic effects of five SYK inhibitors, fostamatinib, entospletinib, cerdulatinib, TAK-659, and RO9021, in a consecutive AML patient cohort. All inhibitors demonstrated a concentration-dependent antiproliferative effect, although there was considerable heterogeneity among patients. For fostamatinib and TAK-659, the antiproliferative effects were significantly higher in FLT3 mutated patients compared to nonmutated patients. Fostamatinib, entospletinib, TAK-659, and RO9021 induced significant apoptosis in primary AML cells, although the proapoptotic effects of the SYK inhibitors were less pronounced than the antiproliferative effects. Finally, most of the SYK inhibitors caused a significant decrease in the release of cytokines and chemokines from primary AML cells, indicating a potent inhibitory effect on the release of these leukemic signaling molecules. We concluded that the SYK inhibitors had antileukemic effects in AML, although larger studies are strongly needed to identify which patient subsets will benefit most from such a treatment.
Oleic Acid Facilitates Cd Excretion by Increasing the Abundance of Burkholderia in Cd-Exposed Mice
Authors: Fang Zhijia , Chen Yinyan , Li Yongbin , Sun Lijun , Deng Qi , Wang Jingwen , Gooneratne Ravi
Published: November 2022

As a global pollutant, cadmium (Cd) can easily enter the body through food chains, threatening human health. Most Cd is initially absorbed in the gut, with the gut microbiota playing a pivotal role in reducing Cd absorption and accumulation. This study assessed the effects of three fatty acids on Cd accumulation and toxicity in Cd-exposed mice. The results showed that oleic acid (OA) was the most effective in facilitating Cd excretion in mice among these fatty acids. The use of OA led to reduced Cd accumulation in the organs and increased Cd content in the feces. The metagenomic analysis of the gut microbiota showed that the genus Burkholderia was the most significantly restored by OA in Cd-exposed mice. Burkholderia cepacia, as the type species for the genus Burkholderia, also exhibited strong Cd tolerance after treatment with OA. Furthermore, the electron microscopy analysis showed that most of the Cd was adsorbed on the surface of B. cepacia, where the extracellular polymeric substances (EPSs) secreted by B. cepacia play a key role, displaying a strong capacity for Cd adsorption. The peak at 2355 cm−1 and the total sulfhydryl group content of EPSs showed significant increases following co-treatment with Cd and OA. The results demonstrated the potential roles that gut Burkholderia may play in OA-mediated Cd excretion in mice.
Influence of Alkali-Activators on Acid Rain Resistance of Geopolymer-Recycled Pervious Concrete with Optimal Pore Size
Authors: Ma Quan , Yang Wei , Duan Zhenhua , Liu Hui , Hua Minqi , Deng Qi
Published: November 2022

Geopolymer-recycled pervious concrete (GRPC) is a novel concrete that can effectively inhibit the corrosion of acid rain and alleviate urban waterlog. The goal of this study is to ascertain the optimal pore size of GRPC and study its acid rain resistance activated by different alkali-activators. Three different sizes (0.8, 1.0, and 1.2 mm) were separately chosen as the pore diameters of GRPC. The alkali-activator solution adopted sodium hydroxide (NaOH), sodium silicate (Na2SiO3), and a mixture of the two. The mechanical properties and permeability coefficient were tested to determine the optimal pore size of GRPC. After that, specimens with the optimal pore size were immersed in a simulative acid rain solution (sulfuric acid solution with pH = 4.0) for 6 d and were dried 1 d until 56 d. The effects of different alkali activators on acid rain resistance of GRPC were analyzed by compressive strength, neutralization depth, and mass loss. The results manifested that the mechanical properties of GRPC were excellent, the compressive strength of GRPCH+N reached more than 60.1 MPa, and their splitting tensile strength attained more than 5.9 MPa, meeting the strength requirement of the road for heavy traffic load. Considering the mechanical properties and the acid rain purification effect of alkaline GRPC required a relatively small permeability coefficient; the optimal pore size was 1 mm. When specimens with optimal pore size were exposed to acid solution, the corrosion products (gypsums) would block the pores of GRPC to inhibit further corrosion, keeping the stability of the compressive strength. GRPC activated by the mixture of NaOH and Na2SiO3 generated a more stable amorphous three-dimensional network structure, endowing GRPCH+N with better mechanical properties and acid corrosion resistance.