bluuebunny/crossref_metadata_2025 huggingface dataset:
A Study of Suicidal Behaviour in Persons with Depressive Disorder
Authors: Parameswari Lalam , Raju T.S.N , V Bodhi Sri Vidya , S Radha Rani
Published: March 2021

BACKGROUND Depression is a major public health problem. Irrespective of socio-economic status, age, education, gender and it exists in every community. Suicidal risk is most common life-threatening situation among depressed individuals. According to World Health Organization (WHO), every year about 1 million people die from suicide and 20 times more people attempt suicide. Up to 50 % of persons with depressive disorder will make a suicide attempt at least once in their lifetime. There is a wide disparity in the rates of suicide across different countries and hence, a greater understanding of region-specific factors related to suicide would enable prevention strategies to be more culturally sensitive. We intended to study suicidal behaviour in depressive disorder in Indian population as understanding of region-specific factors related to suicide helps to plan culturally sensitive preventive strategies. METHODS 130 subjects diagnosed as suffering from depressive disorder according to International Classification of Disease (ICD-10) diagnostic criteria for research, who were having suicidal ideation were selected. The subjects were divided into two groups as suicidal attempters and non-attempters, and analysed using the Hamilton Depression Rating Scale (HAMD) to rate the severity of depression and Hamilton Anxiety Rating Scale (HAMA) to assess severity of anxiety and Columbia Suicide Severity Rating Scale (C-SSRS) was used to assess severity of suicidal behaviour. Columbia risk assessment version was used to determine risk factors and protective factors and a semi-structured proforma was used to collect the socio-demographic details of the participants. RESULTS High HAMA and HAMD score, urban residence, unemployment and agitation were found to be significantly associated with the presence of suicidal attempt. CONCLUSIONS Urban residence, unemployment, severity of depression and anxiety, and agitation were found to be associated with increased risk of suicidal attempts. Responsibility to family or living with family was found to be associated with decreased risk of suicidal attempts. KEYWORDS Suicidal Ideation, Agitation, Depression, Anxiety
Role of Sonography in the Evaluation of Endometrial Aetiology in Abnormal Uterine Bleeding
Authors: Pandey Seema , Kumari Mamta , Chaurasia Amrita , Prakash Gyan
Published: March 2021

BACKGROUND Abnormal uterine bleeding is an important cause of morbidity in the female population, which can be attributed to several reasons. Trans-vaginal sonography and saline-infusion sonography are the mainstay of diagnosis and govern the further management of this condition. This study was conducted to evaluate the thickness and pattern of endometrium with transvaginal sonography and determine any abnormality in the uterine cavity which can be attributed to saline infusion sonography (SIS) in cases of abnormal uterine bleeding (AUB). METHODS The study was conducted among 122 women with complaints of abnormal uterine bleeding attending Outpatient Department and indoor cases of a tertiary care hospital over a period of twelve months. RESULTS The most common presenting complaint was heavy menstrual bleeding in 27.04 % cases. Maximum (44.26 %) cases had normal finding on transvaginal sonography; most common pathological finding was leiomyoma (22.31 %), and endometrial hyperplasia (15.5 %). More than one third (37.7 %) of patients had no abnormalities on saline infusion sonography; while 62.3 % had one or more pathologies; the most common lesion was fibroid in 25.4 % cases. Normal proliferative and secretary endometrium was found on histopathological examination in 50 % cases, while remaining half cases had one or more pathology, most common pathology detected was endometrial hyperplasia in 25.4 % cases. On trans-vaginal sonography (TVS), 11 cases of endometrial polyp were missed, which were detected after infusion of saline and confirmed by histopathological examination. The diagnostic indices of SIS were superior to TVS in diagnosis of any pathology. Sensitivity of TVS was 86.94 % and SIS was 91.94 %. Specificity of TVS (75.41 %) was greater than SIS (68.33 %). CONCLUSIONS TVS and SIS scanning techniques play a very important role in endometrial disorders in woman with AUB. KEYWORDS SIS, Transvaginal, AUB, Endometrium
Updating Health Technology Assessment Report; CBCT Technology: A Review Study
Authors: Arab-Zozani Morteza , Kakehbaraei Somayeh , Akbari-Sari Ali
Published: March 2021

Context: Cone-beam computed tomography (CBCT) is a medical imaging technology with various dental applications and diagnosis of oral and maxillofacial lesions. The current study mainly aimed at updating the safety and efficacy of CBCT technology.
Materials and Methods: This is a systematic review study of available evidence of CBCT technology. Since the time searching in the previous report was up to December 2010, electronic databases including Cochrane Library and Scopus were searched from January 2011 to June 2014. In the first step, based on inclusion and exclusion criteria, title, abstract, and full-text of articles were reviewed by two independent reviewers. In some cases, the full-texts of articles were not available; therefore, the authors of the articles were contacted and the full-texts were obtained. Also, non-English language articles were excluded from the study. The same design of the previous report was employed to extract data and information of the included articles. Due to the heterogeneity in studies, the qualitative and quantitative methods were employed to report the results.
Results: After removing duplicates, a total of 876 articles were included in the study. Finally, 23 studies reached the final analysis stage. In terms of quality, 13 articles were of average quality and 10 articles had good quality. Most of the studies were related to Iran (n = 5), Brazil (n = 4), Germany (n = 3), Britain, USA, Netherlands (n = 2), and Turkey, China, India, and Switzerland (n = 1). The included studies were conducted in 2011 (n = 8), 2012 (n = 6), 2013 (n = 5), and 2014 (n = 4). Totally, 1806 samples were reviewed in all the included studies. The most important reported results included sensitivity, specificity, accuracy, positive and negative predictive values, and area under the curve; 86.3% of the studies reported sensitivity and specificity (n = 19), accuracy (n = 8), and area under the curve (n = 8). Positive and negative predictive values were 36.3% and 27.2%, respectively.
Conclusions: CBCT is a highly sensitive imaging tool for the diagnosis of various oral lesions. However, due to the limited number of clinical trials and the lack of evidence, further studies are needed to obtain more conclusive results.
Evaluation of seizures and clinical features of pediatric patients diagnosed with Rett Syndrome who were detected to have MECP2 mutation
Authors: KIRIK Serkan , ASLAN Mahmut , ÖZGÖR Bilge , GÜNGÖR Serdal
Published: March 2021

Rett syndrome is a neurodevelopmental disorder largely seen in girls. It occurs as a result of the mutations in methyl CpG binding protein 2 (MECP2) gene on X chromosome. The disease shows itself with psychomotor retardation and purposeless hand movements that are developed after normal development stages between months 6-18. It is frequently accompanied by microcephalia. Rett syndrome diagnosis is a clinical diagnosis, and molecular analysis is a supportive element for diagnosis. In this study, we have investigated seizures and clinical features of 9 patients monitored in our third line pediatric neurology clinic with Rett Syndrome diagnosis. Increased awareness provides early diagnosis and suitable treatment for female patients applied with otism and microcephalia in particular, and it is also important for preventing unnecessary diagnostic tests.
The European Union’s Position in Global Foreign Direct Investment Flows and Stocks: Institutional Attempts to Improve It
Authors: Witkowska Janina
Published: March 2021

Global flows of foreign direct investment (FDI) have slowed down in recent years, which particularly affected developed countries, including those in the European Union (EU). A general decrease in capital circulation in the form of FDI between the EU and the rest of the world has been observed. The aim of this paper is to assess the changes in the EU’s position in global FDI flows and stocks and to discuss attempts made by EU institutions and the EU member states to improve this position. The EU can use the common investment policy to strengthen its investment position. The EU acquired the competence to conduct this policy based on the Lisbon Treaty, while its actual shape was determined in practice. Improving the EU’s position in global FDI flows requires agreements regarding foreign investment, concluded at the EU level with other countries and integration groupings. Ensuring national treatment of investors before and after investing is important, as are solutions used for inwestor protection, inwestor-state-dispute-settlements (ISDS), and the use of investment project screening to protect strategic sectors of the EU economy. The EU investment policy can mitigate the effects of slowing down FDI flows, create a more favorable climate for outgoing FDI, and protect vital interests for FDI coming into the EU from third countries.
The Development of Corporate Social Responsibility in the Context of Overcoming a Welfare State Crisis: a Theoretical and Empirical Analysis
Authors: Grazhevska Nadiia , Mostepaniuk Alla
Published: March 2021

The current social crisis, caused by the negative consequences of globalization, labor migration, and an aging population, requires the state’s role in economic and social spheres to be reconsidered. In order to achieve and maintain sustainable economic growth, the pressing social problems, such as poverty, hunger, discrimination, and the unequal distribution of income, should be solved. Under these circumstances, the paper investigates the process of forming a welfare state to evaluate the role of current states in this period of social crisis. To achieve the aim, the following methods were used: historical and systematic analysis of the scientific literature and socio-economic conditions of the evolution of theoretical approaches of the welfare state, and the causes and characteristics of the present social crisis; cluster analysis of European countries to find similar patterns based on the level of corporate social responsibility (CSR) development, state social expenditures, and the government budget balance. The paper contains a detailed analysis and discussion of the formation of a welfare state. The study concludes that the process of delegating some state social services to the private sector in the form of CSR can be considered an efficient mechanism to eliminate and overcome the current social crisis through the accumulation of social capital. At the same time, the results of the cluster analysis of European countries demonstrated the importance of CSR development as a compensator for the negative effects of a public welfare crisis and for solving pressing social problems in most European countries. Specific features of post-socialist countries in the context of social orientation of state policy and the development of CSR are highlighted.
ВЕЩЕСТВЕННЫЙ СОСТАВ ТОРФОВ ТИМИРЯЗЕВСКОГО БОЛОТА (ТОМСК, ЗАПАДНАЯ СИБИРЬ)
Authors: Савичев Олег Геннадьевич , Рудмин Максим Андреевич , Мазуров Алексей Карпович , Федченко Артем Сергеевич , Рубан Алексей Сергеевич , Даулетова Айгерим Бауыржановна
Published: March 2021

Актуальность. Болота одновременно являются индикатором состояния окружающей среды в целом и связанных с болотами речных и подземных вод в частности. Это определяет необходимость изучения состояния болот, особенно в районе размещения крупных водозаборов, например, Томского подземного водозабора. Цель: выявление изменений по глубине торфяной залежи Тимирязевского болота (западная окраина г. Томска, Западная Сибирь) химического состава торфов (кислотных вытяжек) и ассоциаций минеральных включений в торфяной залежи как индикаторов природно-антропогенных условий формирования болота. Методы: методы определения химического (включая масс-спектрометрический с индуктивно связанной плазмой) и минерального состава (сканирующая электронная микроскопия с локальным энергодисперсионным анализом), статистические методы. Результаты и выводы. Для переходного Тимирязевского болота в долине реки Томь у г. Томска выявлено неоднородное изменение зольности, Al, Ti, Cr и ряда других элементов с максимумами в верхней и нижней частях торфяной залежи пропорционально источнику минерального вещества (в верхней части залежи – пылевые выпадения, в нижней подстилающие грунты). С учетом данных, ранее полученных на Васюганском болоте, сделано предположение о наличии общего механизма формирования вещественного состава торфов и трансформации минерального вещества в болотах на основе фильтрационных свойств среды. Основные черты указанного выше механизма заключаются в биохимической трансформации минеральных веществ, поступающих из атмосферы, с поверхностным и подземным стоком с суходолов, в результате чего в деятельном горизонте вещество находится во взвешенном, коллоидном и растворенном состоянии, а в инертном горизонте с большей интенсивностью формируются минеральные фазы. На поверхности последних, а также на частицах гидроокислов происходит соосаждение ряда микроэлементов и формирование аутигенных минералов, в том числе фосфатов редкоземельных элементов. Скорость и направленность этих процессов зависит от геоморфологических и гидрологических условий, определяющих возникновение и функционирование геохимических барьеров.
ИССЛЕДОВАНИЕ МЕТОДОВ ИНТЕНСИФИКАЦИИ ДОБЫЧИ НЕФТИ ИЗ НИЖНЕМЕЛОВЫХ ОТЛОЖЕНИЙ ГОРЯЧЕИСТОЧНЕНСКОГО МЕСТОРОЖДЕНИЯ
Authors: Бакраев Мубарик Мовлаевич , Булюкова Флюра Зиннатовна , Думлер Елена Борисовна , Дельбиев Айнди Сайдиевич
Published: March 2021

Актуальность. На современном этапе перед нефтедобывающей отраслью стоят серьезные задачи по поиску новых эффективных технологий по повышению нефтеотдачи пластов. В процессе разработки нижнемеловой залежи нефти наблюдается тенденция значительного снижения дебита скважин за счет отложений в насосно-компрессорных трубах труднорастворимых асфальтеносмолистых веществ. С падением дебита, давления и температуры интенсивность отложений, в том числе кольматирующих элементов в призабойной зоне пласта, увеличивалась. В статье решается задача подбора эффективного способа обработки призабойной зоны с целью повышения интенсификации добычи и увеличения нефтеодачи пласта за счет более полной ее очистки от трудноудаляемых кольматирующих отложений. Основной целью исследования является определение наиболее эффективного способа обработки терригенных коллекторов нижнемеловых залежей для воздействия на скелет горной породы, образующей коллектор, и защиты от кольматирующих отложений. Объект: Горячеисточненское месторождение, расположенное на восточном окончании Терского хребта Грозненского района Чеченской республики. Месторождение многопластовое. В разработке и эксплуатации пребывали миоценовая, верхнемеловая, альбская, альб-аптская и барремская залежи. Наиболее крупные объекты связаны с верхнемеловыми и альб-аптскими отложениями нижнего мела. Миоценовая залежь практически выработана. Альбская и барремская залежи недоразведаны и эксплуатируются единичными скважинами. Продуктивные отложения альб-аптской залежи характеризуются сравнительно низкими коллекторскими свойствами. Методы: исследование различных технологических методов воздействия на призабойную зону пласта скважины. Результаты. С целью интенсификации добычи и увеличения нефтеодачи пласта предлагается производить обработку терригенных коллекторов нижнего мела органическими растворителями РИНГО-ГКС, РИНГО-СКС и МКС. Экспериментальные обработки в скважинах показали эффективность воздействия на призабойную зону и полную её очистку от кольматирующих отложений.
Novel alternative splice variant of IGF-1R and its mRNA expression patterns in BaMa and Landrace pigs
Authors: Yang Rui , Dong Lijie , Liu Songcai , Cheng Yunyun , Wei Wenzhen , Song Jie , Li Haoyang , Geng Hongwei , Hao Linlin , Zhang Ying
Published: March 2021

The transcript variants of Insulin-like growth factor 1 receptor (IGF-1R) and their expression profiles had never been illuminated in pigs until now. Herein, we identified IGF-1R AS02 as a novel splice variant of IGF-1R gene by RT-PCR and analyzed its mRNA expression level by qRT-PCR in liver, cartilage and muscle tissues, while also detecting the single-nucleotide polymorphism (SNP) site near the splice site of the IGF-1R gene (in intron 19) of BaMa and Landrace pigs. Results demonstrated that the IGF-1R AS02 variant showed a significantly (P less than 0.05) higher expression level in cartilage than in muscle and liver across two pig breeds respectively. The expression level of the normal transcript (IGF-1R ISO01) of IGF-1R in cartilage was markedly lower than that in the other two tissues (P less than 0.05). In cartilage, IGF-1R ISO01 expression was higher in BaMa than in Landrace (P less than 0.05), while the expression level of IGF-1R AS02 was lower in BaMa than in Landrace (P less than 0.05). The SNP was detected in intron 19 of the IGF-1R gene of BaMa and Landrace pigs. These results contributed to facilitating a better understanding of IGF-1R gene in pigs.
Impact of Hatching Egg Disinfection on Hatching Characteristics and Chick Embryos
Authors: Bekhet Gamal M.
Published: March 2021

Four thousand two hundred hatching eggs were obtained from Bandarah chicken to evaluate the effect of chemical and natural egg disinfectants and fumigation on egg weight loss, embryonic mortality, hatchability, hatch time, chick weight and chick weight loss. Three incubation trials were done; each one contained 1400 hatched eggs and divided into fourteen treatments (100 eggs per each). First treatment (T1) was used as control without any treatment, eggs of second treatment (T2) were dipped in water and third treatment in alcohol, whereas T4, T5, T6, T7 treated egg groups were dipped in chemical disinfectant (sodium chloride, betadine, hydrogen peroxide, virkon S). Egg of T9, T10, T11, T12, T13 and T14 groups were dipped in natural disinfectants (oregano, cumin 02 and 04 % and oregano+ cumin01 and 02), respectively. The thickest eggshell (031mm) was recorded for betadine group in infertile eggs compared with those for formaldehyde fumigation and oregano+cumin 01% oregano+cumin 01% group (035mm) compared with all other treatment groups. Formaldehyde fumigation recorded the worst and highest significant percentage of embryonic mortality (1795%). Highest significant percentages for hatchability of fertile egg were recorded in egg groups with oregano 02 and 04% (9687 and 9576%), cumin 02 and 04 % (9551and 9715%) and oregano+cumin01 and 02% (9619 and 9615%), respectively.
The Histochemical Study of the Thyroid Gland of Chabro Chicken Reared in Summer and Winter Seasons
Authors: Vishen Amit Singh , Gupta Varsha , Singh S.P. , Verma Abhinov , Yadav Renu , Gupta Rakesh Kumar , Singh K.N. , Kumar Mukesh , Singh Anand
Published: March 2021

Background: Chabro is a strain of poultry birds especially designed for backyard farming and is more adoptive to climatic variations in the tropics. The thyroid gland plays an important role in controlling basal metabolic rate. Histochemical changes of the gland in association with seasonal changes have not been studied so far in Chabro chicken. The present study describes the season related variations in the histochemistry of thyroid gland. Methods: The histochemical study was conducted on thyroid gland of eight to ten weeks old 24 apparently healthy Chabro chickens procured from Poultry Farm, DUVASU, Mathura. The birds were divided into two groups consisting of 12 chickens in each group reared in summer and winter seasons. Result: The capsule showed mild reaction for PAS, protein and glycogen. Follicular cells showed intense reaction for bound lipids, protein and alkaline phosphatase. The colloid in summer season showed strong reaction for PAS at periphery and very strong reaction at center while in winter colloid showed strong PAS positive activity. The Chabro chicken thyroid was functionally more active in winter as compared to summer season because of increased diameter of all follicles and concentration of thyroid hormones level in winter season.
ŞİDDET VE DİJİTAL OYUNLAR (ŞİDDETİN DİJİTAL OYUNLAR ÜZERİNDEN DENEYİMLENMESİ)
Authors: VATANDAŞ Saniye
Published: March 2021

İnsan hep şiddetten yakındı ve yakınmaya devam ediyor. Fakat son derece manidar olan şey; şiddeti gerçek-leştirenin de şiddetin varlığından yakınanın da insan olması. Şiddetin öznesi de insan, çoğunlukla nesnesi de. Şiddeti yok etmeye çalışan da insan, şiddete her yeni günde yeni boyutlar kazandıran da. Bu niçin böyle oluyor? İnsan acısını yaşadığı ve şikâyetçi olduğu şiddetten neden vaz geçemiyor? Bu, konunun ilgilileri ve uzmanlarınca cevabı aranmış ve aranmaya devam eden bir sorudur. Çünkü her cevabı haklı çıkaracak bir yan var; ancak hiçbir cevap tek başına gerçeği bütün boyutlarıyla ifade etme başarısına sahip değil. Fakat bu arada şiddet çeşitlenerek ve yoğunlaşarak devam ediyor. Hal böyleyken şiddet, özellikle son 20-30 yıldır, gittikçe artan bir yoğunlukla dijital oyunlar ve internet aracılığıyla başta çocuklar olmak üzere, hemen herke-sin daha da yoğun bir şekilde gündeminde yer almaya başladı. Çocuklar her anı şiddet ile donatılmış sanal ortamın öznesi olarak ‘öldürdüklerinin’, ‘imha ettiklerinin’, ‘patlattıklarının’… skoruyla övünür oldular. Bu çalışmada internet teknolojilerinin gelişimine bağlı olarak şiddetin değişim ve dönüşüm süreçleri incelenecek. Bu bağlamda özellikle de dijital oyunların internet teknolojisi üzerinde ulaştıkları aşamayı temsil eden sanal şiddetin her bireyin ve özellikle çocukların gündemindeki yeri ve yol açtığı riskler konu edinilecek. Zira dijital oyunlara tutku düzeyinde ilgili olanlar arasında başkasına veya kendine fiziksel zarar verme ve hatta yaşamını sonlandırma eylemleri sıklıkla işitilir hale gelmiştir.
ULUSLARARASI MEDYADA SİNCAN/DOĞU TÜRKİSTAN HABERLERİNİN ÇERÇEVELENMESİ
Authors: GÜVEN Ahmet
Published: March 2021

Türkiye’de Doğu Türkistan sorunu olarak bilinen Çin’in, Sincan Uygur Özerk Bölgesi’ndeki sorunlar, eskiden beri gündemde olmasına rağmen son yıllarda özellikle Çin’in “asimilasyon politikaları” çerçevesinde kurduğu iddia edilen “toplama kamplarının” faaliyete geçmesiyle birlikte daha aktif bir şekilde uluslararası kamuoyunun gündemine gelmiştir. Çin ise söz konusu kampların birer “meslek eğitim merkezi” olduğunu savunarak, iddiaları reddetmektedir. ABD ile Çin arasındaki stratejik ve ekonomik mücadele göz önünü alındığında Sincan meselesi bu mücadelenin görünür olduğu önemli alanlardan biri haline gelmiştir. Uygurlarla hem soy hem din hem de dil birliği taşıması itibariyle Türkiye’deki kamuoyunun ve yönetimin konu hakkında takındığı tavır tüm aktörler açısından oldukça önemlidir. Dolayısıyla uluslararası medya kuruluşlarının Türkiye kamuoyuna yönelik olarak yapmış olduğu Sincan haberleri stratejik anlamda önem taşımaktadır. Bu çalışmada Türkçe yayın yapan Amerika menşeli Voice of Amerika (VOA), Alman menşeli Deutsche Welle (DW), Çin menşeli China Radio International (CRI Türk) ve Rus menşeli Sputnik Türkiye’nin Sincan ile ilgili yaptığı haberlerinde nasıl bir çerçeveleme yaptığı incelenmiştir. İnternet sitelerinde Sincan üzerine yapılmış olan beşer haber (toplamda yirmi haber) incelenerek VOA ve DW’nin “insan hakları ihlalleri” ana çerçevesini CRI Türk ve Sptnik Türkiye’nin “terörle mücadele” ana çerçevesini kullandığı sonucuna varılmıştır. Ayrıca VOA’nın “asimilasyon”, “zulüm”, “tepkisizlik” ve “Türkiye”; DW’nin “asimilasyon”, “zulüm” ve “Türkiye”; CRI Tük ve Sputnik Türkiye’nin “terör”, “savunma”, “kalkınma” ve “Türkiye” alt çerçevelerini kullandıkları görülmüştür. Her dört medya kuruluşunun da alt çerçevesinde “Türkiye”nin yer alması Sincan sorununda uluslararası medyanın Türkiye’ye verdiği önemi göstermektedir.
REKLAMLARDA EMOJİ KULLANIMININ BEĞENİ DÜZEYİNE ETKİSİ: ÜNİVERSİTE ÖĞRENCİLERİ ÜZERİNE UYGULAMALI BİR ÇALIŞMA
Authors: ÇEVİKYİĞİT Gülcan
Published: March 2021

Sanal alemde ifadelerin karikatürleştirilmesi ile elde edilen şekillerden oluşan emoji dilinin şekil sayısı ve kullanım yoğunluğu son yıllarda hızlı bir artış göstermiştir. İlerleyen teknoloji, çevrimiçi nüfusun çok büyük kısmının emojileri sistemli ve istikrarlı olarak kullanması, kelimelerin kifayetsiz kalması durumlarında ruh halini ifade edecek işaretlere ihtiyacın açığa çıkması, duyguları uzun sözcüklerle ve cümlelerle anlatmaya gerek kalmadan tanımlanmış ve şekle dönüştürülmüş hazır ifadelerin olması ve emojilerin ifade ettikleri manaların herkes tarafından anlaşılır olması gibi faktörler bu büyümenin sebepleri arasında yer almaktadır. Dünyada en çabuk büyüyüp gelişen dil olma özelliğine sahip emoji dili, reklamların işlevlerini yerine getirebilmeleri, hedef kitlesine ulaşarak istenilen etkiyi sağlayabilmesi için kendine özgü nitelikleri olan reklam dilinde de kendine yer bulmuştur. Çalışma kapsamında emoji sözcüğünün anlamı, emojilerin işlevleri ve kullanım biçimleri ele alınacaktır. Bu bağlamda emojilerin dilsel yapıları ve sözsüz iletişim şekli olarak işlevleri incelenecektir. Reklam iletilerinde emoji kullanımının beğeni düzeyine etkisi ve emoji dili ile oluşturulan reklamların izleyiciler tarafından nasıl değerlendirildiğini ortaya koymak amacıyla Selçuk Üniversitesi İletişim Fakültesi öğrencilerinin örneklem olarak belirlendiği alan araştırması gerçekleştirilmiştir. Araştırma sonucunda emojilerin dijital iletişimde yaygın olarak kullanıldığı ve emojili reklamların izleyicilerin beğeni düzeyine olumlu yönde etki ettiği; tutumlarının olumlu yönde etkilendiği tespit edilmiştir.
NEDENE DAYALI PAZARLAMADA MARKA-SİVİL TOPLUM KURULUŞU İŞBİRLİĞİ: HAYTAP ÖRNEĞİ
Authors: BOYACI YILDIRIM Merve
Published: March 2021

Günümüzde tüketicilerin satın alma tercihlerini yalnızca fonksiyonel özelliklere dayanarak değil marka ile kurulan duygusal nedenlerle de ilişkilendirmesi, markaların pazarlama çabalarını yerine getirirken aynı zamanda sosyal sorumlu kurum davranışları sergilemelerini zorunlu kılmaktadır. Markalar, nedene dayalı pazarlama uygulamaları ile hem sosyal sorumluluk faaliyetlerini gerçekleştirmekte hem de satışlarını da artırarak kâr etme olanağına sahip olmaktadır. Markaların nedene dayalı pazarlama uygulamalarını gerçekleştirirken kampanya süresince dikkat çekilen sosyal “neden” çerçevesinde kurulmuş olan sivil toplum kuruluşları ile işbirliği yapması kampanyanın etkinliğini artırabilmektedir. Bu bağlamda çalışmada Hayvan Hakları Federasyonu (HAYTAP) sivil toplum örgütünün nedene dayalı pazarlama uygulamaları kapsamında iş birliği yapmış olduğu çeşitli markalar ve gerçekleştirilen projeler içerik analizi ile incelenmiştir. Araştırma bulgularına göre gerçekleştirilen tüm projelerde ürün satışlarından elde edilen gelirlerin bir kısmının sahipsiz hayvanların hayat koşullarını iyileştirmek üzere HAYTAP’a bağışlandığı ifade edilebilmektedir. Bu projeler sayesinde HAYTAP ayni ve maddi yardımlar sağlarken aynı zamanda sivil toplum örgütünün daha görünür olduğu ve gönüllü sayısını artırdığı, markaların ise hem ürün satışlarını artırıp hem de hedef kitlelerde daha olumlu bir şekilde algılanmasına yardımcı olduğu söylenebilmektedir.
SİYASAL REKLAMCILIĞA AYRINTILANDIRMA OLASILIĞI MODELİ BAĞLAMINDA MERKEZİ VE ÇEVRESEL İKNA ARGÜMANLARI ÜZERİNDEN FARKLI BİR BAKIŞ: 31 MART 2019 İSTANBUL YEREL SEÇİMLERİ ÖRNEĞİ
Authors: ARKLAN Ümit , SANDIKCI Yılmaz Türker , SOY Samed
Published: March 2021

Geniş seçmen kitlelere ulaşım aracı olarak özellikle seçim dönemlerinde yoğun biçimde kullanılan siyasal reklamlar, siyasal aktörler tarafından müracaat edilen önemli bir siyasal iletişim uygulamasıdır. Konvansiyonel medyadan yeni iletişim ortamlarına dek geniş bir yelpazede ikna edici mesaj kurgularını ve bu kapsamda hazırlanan argümanları ilgili kitlelere ulaştırarak istenen yönde kanaat ve davranış inşası amacı taşımaktadır. Çoğu zaman profesyonel ekiplerce, seçmen profilleri göz önünde bulundurularak onların ikna olacağı düşünülen yollar tercih edilmekte ve mesajlar dizayn edilmektedir. Söz konusu bağlamdan yola çıkan bu çalışma, siyasal reklamcılığa Ayrıntılandırma Olasılığı Modelinden (AOM) hareketle farklı bir bakış açısı getirme amacı taşımakta, odağına da merkezi ve çevresel ikna argümanlarının kullanımını almaktadır. Bu amaç doğrultusunda, 31 Mart 2019 İstanbul yerel seçimleri öncesinde Cumhur İttifakı adayı Binali Yıldırım’ın ve Millet İttifakı adayı Ekrem İmamoğlu'nun resmi YouTube kanallarında yayınladıkları siyasal reklamları betimsel analize tabi tutulmaktadır. Analiz sonucunda, Binali Yıldırım’ın reklamlarında hem çevresel yola hem de merkezi yola daha yoğun başvurarak argüman geliştirmekle birlikte, her iki adayın da merkezi ikna argümanları kullanımının tespit edildiği kategoriler mevcut olsa da ağırlıklı olarak çevresel ikna argümanları üzerinden seçmen kitlelerde tutum ve davranış değişliği oluşturmaya çalıştıkları saptanmıştır.
COR VERSUS GÊNERO:ANÁLISE DISCURSIVA DO DISCURSO DE BOLSONARO NO MARANHÃO E COMENTÁRIOS DE INTERNAUTAS
Authors: CAVALCANTI MARIA DO CARMO GOMES PEREIRA , AZEVEDO NADIA PEREIRA GONÇALVES DE
Published: March 2021

Este trabalho analisa a reportagem do Jornal Nacional exibida em 29/10/2020, acerca do discurso do presidente sobre a cor rosa do refrigerante Jesus no Maranhão, e dois comentários de internautas no site da Folha de Pernambuco, no mesmo dia. Assim, à luz do dispositivo teórico e analítico da Análise do Discurso de linha francesa baseado nos estudos de Pêcheux na Europa, e de Orlandi e demais estudiosos no Brasil (AD), este artigo mobiliza as noções de sujeito, memória discursiva, formações imaginárias e discursivas, efeito metafórico, que funcionam como unidades de sentido em relação à situação.
Hubungan Paparan Sinar Matahari, Status Gizi, dan Asupan Makan terhadap Kadar Vitamin D Anak dan Remaja Penderita Diabetes Mellitus Tipe 1
Authors: Kusumastuty Inggita , Handayani Dian , Tjahjono Harjoedi Adji , Sari Elsa Permata , Rahayuningtyas Silvy Kartika , Saputra Andanu Bima
Published: March 2021

Background: Previous research state the correlation between vitamin D deficiency and Type 1 diabetes. The deficiency of Vitamin D is caused by vitamin D intake, sunlight exposure, or nutritional status. Indonesia, as a tropical country, is close to the equator and receives sunlight all year long. Little research has been done on vitamin D levels in children and adolescents with Type 1 Diabetes in Indonesia.Objective: The study aims to determine the relationship among sunlight exposure, nutritional status, food intake, and vitamin D levels in children and adolescents with Type 1 Diabetes.Methods: The study design was cross-sectional with a sample size of 31 children and adolescents aged 5-19 years. Sunlight exposure data were collected using the Sun Exposure Questionnaire form, nutritional status o BMI/age data were using the WHO Anthro, food intake data were using the Semi-Quantitative Food Frequency Questioner, and vitamin D level data were using the ELISA method. Statistical analysis was conducted by using SPSS Version 21 with Pearson and Spearman correlation test.Results: All respondents showed vitamin D deficiency. Most respondents had low sunlight exposure and nutritional status in the normoweight category. The majority of respondents had good energy and protein intake, excess fat, low carbohydrates, and low vitamin D and calcium.Conclusion:There is a positive relationship between sunlight exposure and vitamin D level (p = 0.001, r = 0.627). However, there is no relationship among nutritional status, protein intake, fat, carbohydrates, vitamin D and calcium on the level of vitamin D (p = 0.409; p = 0.240; p = 0.311; p = 0.822; p = 0.231; 0.382).
Modifikasi Kacang Kedelai (Glycine Max) dan Hati Ayam Pada Sosis Ayam Sebagai Alternatif Sosis Tinggi Protein dan Zat Besi
Authors: Lutfiah Annisa , Adi Annis Catur , Atmaka Dominikus Raditya
Published: March 2021

Latar Belakang: Hati ayam merupakan sumber zat besi yang baik dan kacang kedelai adalah jenis kacang-kacangan kaya protein dan besi yang dapat diolah menjadi sosis sebagai snack ataupun lauk tinggi protein dan zat besi.Tujuan: Tujuan penelitian ini untuk menganalisis hasil mutu hedonik, daya terima, kadar protein dan zat besi pada sosis dengan substitusi hati ayam dan kacang kedelai.Metode: Jenis penelitian ini yaitu experimental murni dengan rangangan acak lengkap (RAL). Terdapat 4 jenis formula, yaitu formula kontrol F0 (ayam) dan 3 formula modifikasi F2 (35 g hati ayam dan 65 g kacang kedelai), F3 (45 g hati ayam dan 55 g kacang kedelai), F4 (55 g hati ayam dan 45 g kacang kedelai) dengan pengulangan 4 kali. Panelis penelitian terdiri dari 5 panelis terbatas dan 27 panelis tidak terlatih.Hasil: Berdasarkan hasil penilaian panelis terbatas pada uji mutu hedonik adalah formula F2, F3, dan F4. Hasil uji daya terima, formula yang paling disukai panelis tidak terlatih adalah formula F4. Kandungan protein dan besi pada 100 g sosis F4 yaitu 17,21 g dan 7,415 mg. Terdapat perbedaan signifikan antara F0 dan F4 pada karakteristik aroma (p = 0,045), kekenyalan (p < 0,000) dan rasa (p < 0,000).Kesimpulan: Formula dengan tingkat mutu hedonik terbaik terdapat pada formula F2, F3 dan F4. Formula dengan daya terima tertinggi terdapat pada F4. Satu porsi (33 g) dapat mencukupi 10 – 15 % dari kebutuhan protein dan besi pada remaja putri berusia 16 – 21 tahun.
Damage of the Muscle System in Covid-19
Authors: Murkamilov I. T. , Aitbaev K. A. , Kudaibergenova I. O. , Fomin V. V. , Murkamilova Zh. A. , Yusupov F. A.
Published: March 2021

Статья посвящена поражению мышечной системы при новой коронавирусной инфекции (COVID-19). Проведен анализ литературы российских и иностранных исследователей по внелегочным проявлениям COVID-19. Главной мишенью COVID-19 (Corona Virus Disease 2019) является эндотелий сосудов. Для проникновения в клетки вирус использует рецептор — ангиотензинпревращающий фермент 2 (АПФ2). Показано, что к одной мишени могут присоединиться до трех вирусов. В скелетной мускулатуре также имеется АПФ2. При COVID-19 вовлечение в патологический процесс мышечной системы является предиктором неблагоприятного прогноза. В 20 % случаев среди госпитализированных пациентов COVID-19 выявляются лабораторные признаки повреждения сердечной мышцы. К основным механизмам повреждения мышечной системы при COVID-19 относятся АПФ2-зависимый механизм, степень вирусной нагрузки, цитокиновый шторм, острая гипоксемия и лекарственная токсичность. Поражение мышечной системы при COVID-19 служит дополнительным фактором риска смерти. В представленной работе приводятся сведения о возможных патогенетических механизмах развития миопатии, а также мышечной слабости при COVID-19, протекающие с повышением содержания креатинкиназы крови.
PE. VAZ, A TRADIÇÃO OCIDENTAL E O BRASIL
Authors: Domingues Ivan
Published: March 2021

O objetivo é evidenciar o liame do pensamento e da obra de Pe. Henrique Cláudio de Lima Vaz (doravante Pe. Vaz e Vaz, simplesmente) com a chamada tradição filosófica ocidental, ao fazer seu escrutínio crítico, perguntar por sua originalidade e, por fim, indagar pelo modo como ele pensa o seu alinhamento com a tradição e a inserção do Brasil.
PRESENÇA DE HENRIQUE CLÁUDIO DE LIMA VAZ NO HORIZONTE FILOSÓFICO DA CULTURA BRASILEIRA CONTEMPORÂNEA
Authors: Mac Dowell João A.
Published: March 2021

Abertura do número especial de Síntese, comemorativo do centenário do nascimento de quem foi a alma da revista durante quase três décadas, este artigo, depois de fornecer o elenco das comemorações programadas, faz, na sua primeira parte, um levantamento da avaliação da obra filosófica de Lima Vaz em textos relativos à filosofia no Brasil, verificando, em seguida, qual é efetivamente a sua presença no cenário filosófico atual. Finalmente, após projetar a problemática, que se prevê dominante no meio filosófico brasileiro ao longo do século XXI, conclui que o pensamento de nosso filósofo tem chances de permanecer vivo, iluminando tais questões e inspirando soluções.
TOMÁS DE AQUINO INTÉRPRETE DA TRADIÇÃO EUDAIMONISTA, SEGUNDO MANUSCRITO INÉDITO DE HENRIQUE CLÁUDIO DE LIMA VAZ
Authors: Filho Juvenal Savian
Published: March 2021

Visa-se apresentar aqui a exegese inédita, feita por Henrique Cláudio de Lima Vaz, da posição tomasiana que articula a beatitude e a destinação do espírito segundo a especificidade da “personalidade científica de Santo Tomás”, a qual, como descreve o próprio Lima Vaz, é formada por uma exploração de todas as grandes correntes de ideias que confluíram para o século XIII, funda- mentalmente a aliança ambígua de Aristóteles entre platonismo e empirismo, o neoplatonismo, com as mediações árabes, e a tradição bíblica que forneceu a Tomás um novo fermento para ampliar a fenomenologia aristotélica da beatitude em um movimento inteiramente natural, convergente para o alto e que se estreita, porém, à medida que avança, chegando a um vértice no qual o Universo é síntese inteligível no espírito, o qual, por sua vez, atinge seu Princípio, o seu próprio Bem, íntimo e transcendente.
A Statistical Model to Assess the Team's Productivity in Agile Software Teams
Authors: Mashmool Amir , Khosravi Samiyeh , Joloudari Javad Hassannataj , Inayat Irum , Javdani Gandomani Taghi , Band Shahab S.
Published: March 2021

Agile methods promise to achieve high productivity and provide high-quality software. Agile software development is the most important approach that has spread through the world of software development over the past decade. Software team productivity measurement is essential in agile teams to increase the performance of software development. Due to the prevalence of agile methodologies and increasing competition of software development companies, software team productivity has become one of the crucial challenges for agile software companies and teams. Awareness of the level of team productivity can help them to achieve better estimation results on the time and cost of the projects. However, to measure software productivity, there is no definitive solution or approach whether in traditional and agile software development teams that lead to the occurrence of many problems in achieving a reliable definition of software productivity. Hence, this study aims to propose a statistical model to assess the team’s productivity in agile teams. A survey was conducted with forty software companies and measured the impact of six factors of the team on productivity in these companies. The results show that team effectiveness factors including inter-team relationship, quality conformance by the team, team vision, team leader, and requirements handled by the team had a significant impact on the team’s productivity. Moreover, the results also state that inter-team relations affect the most on software teams’ productivity. Finally, the model fit test showed that 80% of productivity depends on team effectiveness factors.
Quality Evaluation of Winery By-Products from Ionian Islands Grape Varieties in the Concept of Circular Bioeconomy
Authors: Xagoraris Marinos , Oikonomou Ioanna , Daferera Dimitra , Kanakis Charalambos , Lappa Iliada K. , Giotis Charilaos , Pappas Christos S. , Tarantilis Petros A. , Skotti Efstathia
Published: March 2021

The aim of this work was the study and evaluation of winery by-products in the framework of circular bioeconomy. Grape seeds and grape skins from Greek traditional Ionian Islands varieties were analyzed in an attempt to provide the appropriate basis for model development of their sustainable exploitation at a local or regional level. The wastes collected directly from the wineries immediately after the vinification process and analyzed by chromatographic and spectroscopic techniques. Also, annual production and yields were estimated. Grape seed oil quality was evaluated based on fatty acid methyl esters (FAMEs) composition. Grape skins phenolic fraction was extracted by an eco-friendly, non-toxic water-glycerol solvent system and were detected qualitatively. Also, total phenolic content (TPC) and antioxidant activity were measured. Based on estimated yields, our results demonstrate that winery by-products have the potential to promote the cyclical bioeconomy in a modern economic growth model that will reduce waste, and environmental costs as they can be reused as whole material in foods, dietary supplements, cosmetic ingredients, food colorants and preservatives.
Mobility Patterns of the Portuguese Population During the First Year of the COVID-19 Pandemic: A Longitudinal Study
Authors: Tamagusko Tiago , Ferreira Adelino
Published: March 2021

This study analyzes the relationship between the spread of the SARS-CoV-2 virus (COVID-19) and the mobility patterns of the Portuguese population. By reducing mobility, the idea is that contacts are reduced, countering the spread of the virus in the community. As an indicator of the spread of the virus, the reproduction number (Rt) was used. Data from Google's Community Mobility Reports was used to evaluate changes in mobility patterns. This report uses location data from Android mobile phone users. The locations are divided into retail and recreation, grocery and pharmacy, parks, transit stations, workplaces and residential. In this year of the COVID-19 crisis in Portugal, population mobility patterns have changed over the various phases of the pandemic. At first, all mobility was affected uniformly, with the population avoiding much of the activity outside the home. In a second phase, there was some adaptation, and the areas considered to be of lower risk had less impact, emphasizing the changes in the relationship between daily life and the workplace.
Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures
Authors: Do Minh Aline , Star Alexandra T. , Stupak Jacek , Gélinas Jean-Francois , Li Jianjun , Twine Susan M. , Kamen Amine A.
Published: March 2021

Lentiviral vectors (LVs) are a powerful tool for gene and cell therapy and human embryonic kidney cells (HEK293) have been extensively used as a platform for production of these vectors. Like most cells and cellular tissues, HEK293 cells release extracellular vesicles (EVs). EVs released by cells share similar size, biophysical characteristics and even a biogenesis pathway with cell-produced enveloped viruses, making it a challenge to efficiently separate EVs from LVs. Thus, EVs co-purify with LVs during downstream processing, becoming “impurities” in the context of cell therapy. To characterize EVs from an inducible lentivirus producing cell line, two conditions were studied: non-induced and induced. EVs’ identity was confirmed by transmission electron microscopy and western blot. Seven proteins were identified by mass spectrometry as potential EV markers. Lipid composition of EVs and LVs showed similar enrichment in phosphatidylserine. RNA cargos in EVs showed enrichment in genes involved in viral processes and binding functions. Flow virometry, GTA and ddPCR results also confirmed the heterogenic nature of EVs and LVs populations. These findings provide insights on the product profile of lentiviral preparation and could help develop separation strategies of co-produced EVs.
On Analytic Multivalent Function Associated with Cosine Hyperbolic Function
Authors: MUHAMMAD AZAM
Published: March 2021

In this article, we set up some adequate conditions for analytic functions associated with cosine hyperbolic function. We determine conditions on α such that

1+α (ϰ^(2+P(j-1) ) g^' (ϰ))/(Pg^j (ϰ)),for each j=0,1,2,3

are subordinated by Janowski function, then (g(ϰ))/ϰ^P <cosℏ⁡(ϰ),(ϰ∈C). By choosing specific values of functions g we get some adequate conditions for multivalent starlike function related with cosine hyperbolic.
Profiling of Insulin-like Growth Factor Binding Proteins (IGFBPs) in Obesity and Their Association with Ox-LDL and Hs-CRP in Adolescents
Authors: Rahman Abdur , Hammad Maha M. , Al Khairi Irina , Cherian Preethi , Al-Sabah Reem , Al-Mulla Fahd , Abu-Farha Mohamed , Abubaker Jehad
Published: March 2021

Insulin-like growth factor binding proteins (IGFBPs) are critical modulators of the metabolism. In adults, IGFBPs are associated with obesity and insulin resistance but the association of IGFBPs with metabolic homeostasis in children and adolescents is not fully characterized. In this study we investigated the association of plasma IGFBPs (IGFBP-1, 3 and 7) with weight status, central adiposity and cardiovascular disease markers Hs-CRP and Ox-LDL. A total of 420 adolescents (age 11-14 years) were randomly recruited from public middle schools in Kuwait. IGFBPs were measured using bead-based multiplexing while Hs-CRP and Ox-LDL were measured using ELISA. IGFBP-1 levels were significantly lower in obese and overweight participants compared to normal weight children. Only IGFBP-1 was negatively associated with waist circumference to height (WC/Ht) ratio. IGFBP-1 was negatively correlated with Hs-CRP while IGFBP-3 and IGFBP-7 were negatively correlated with Ox-LDL. These data demonstrate a robust negative association of IGFBP-1, but not IGFBP-3 or -7, with overweight and obesity, and the inflammation marker Hs-CRP. Central adiposity (WC/Ht ratio) was a stronger predictor of IGFBP-1 than BMI-for-age z-score. IGFBP-1 could thus be used as a sensitive predictive diagnostic tool for obesity and its subsequent effects in screening and monitoring of obesity-related metabolic complications in adolescents.
A Novel Approach for Early detection of Alzheimer's disease Based on Multi Level Fuzzy Neural Networks
Authors: Akramifard Hamid , Balafar MohammadAli , Razavi SeyedNaser , Ramli Abd Rahman
Published: March 2021

Timely diagnosis of Alzheimer's diseases(AD) is crucial to obtain more practical treatments. In this paper, a novel approach Based on Multi-Level Fuzzy Neural Networks (MLFNN) for early detection of AD is proposed. The focus of study was on the problem of diagnosing AD and MCI patients from healthy people using MLFNN and selecting the best feature(s) and most compatible classification algorithm. In this way, we achieve an excellent performance using only a single feature i.e. MMSE score, by fitting the optimum algorithm to the best area using optimum possible feature(s) namely one feature for a real life problem. It can be said, the proposed method is a discovery that help patients and healthy people get rid of painful and time consuming experiments. Experiments shows the effectiveness of proposed method in current research for diagnosis of AD with one of the highest performance (accuracy rates of 96.6%), ever reported in the literature.
A Set-theoretic Approach to Modeling Network Structure
Authors: Pfaltz John
Published: March 2021

Three computer algorithms are presented. One reduces a network $\CALN$ to its interior, $\CALI$. Another counts all the triangles in the network, and the last randomly generates networks similar to $\CALN$ given just its interior $\CALI$. But these algorithms are not the usual numeric programs that manipulate a matrix representation of the network; they are set-based. Union and meet are essential binary operators; contained_in is the basic relational comparator. The interior $\CALI$ is shown to have desirable formal properties and to provide an effective way of revealing ``communities'' in social networks.