bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table S1 from Measurement of Endogenous versus Exogenous Formaldehyde–Induced DNA–Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry
Authors: Lai Yongquan , Yu Rui , Hartwell Hadley J. , Moeller Benjamin C. , Bodnar Wanda M. , Swenberg James A.
Published: April 2023

Method accuracy and precision.
Table S3 and S4 from Molecular Pathology of Patient Tumors, Patient-Derived Xenografts, and Cancer Cell Lines
Authors: Guo Sheng , Qian Wubin , Cai Jie , Zhang Likun , Wery Jean-Pierre , Li Qi-Xiang
Published: April 2023

Table S3. Biomarkers for lung origin and colon origins. Table S4. IHC analysis of the outlier models
Supplementary Methods and Reference from Measurement of Endogenous versus Exogenous Formaldehyde–Induced DNA–Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry
Authors: Lai Yongquan , Yu Rui , Hartwell Hadley J. , Moeller Benjamin C. , Bodnar Wanda M. , Swenberg James A.
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary Reference.
Supplementary Figures S1-S3 from Measurement of Endogenous versus Exogenous Formaldehyde–Induced DNA–Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry
Authors: Lai Yongquan , Yu Rui , Hartwell Hadley J. , Moeller Benjamin C. , Bodnar Wanda M. , Swenberg James A.
Published: April 2023

Typical calibration curve used for the quantification of dG-Me-Cys with the linearity from 0.15 to 6.0 fmol (S1); Schematic of rat nose only inhalation chamber (S2); Schematic of primate whole-body inhalation chamber (S3).
Supplementary Tables S1-S9 from A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers
Authors: Jung MoonSun , Russell Amanda J. , Liu Bing , George Joshy , Liu Pei Yan , Liu Tao , DeFazio Anna , Bowtell David D.L. , Oberthuer André , London Wendy B. , Fletcher Jamie I. , Haber Michelle , Norris Murray D. , Henderson Michelle J.
Published: April 2023

A list of cancer cell lines and culture conditions (S1); Clinicopathological characteristics of primary neuroblastoma cohort (S2); Taqman gene expression assay IDs (S3); Gene Ontology biological process terms for the 18 Myc activity signature genes (S4); Univariate Cox regression analysis of prognostic factors in a neuroblastomas microarray dataset (S5); Multivariate Cox regression analysis of prognostic factors in a breast cancer microarray dataset (S6); Multivariate Cox regression analysis of prognostic factors in a DLBCL microarray dataset (S7); Multivariate Cox regression analysis of prognostic factors in a medulloblastoma microarray dataset (S8); Distribution of high signature score in medulloblastoma molecular subgroups (S9).
Figure S1 from Molecular Pathology of Patient Tumors, Patient-Derived Xenografts, and Cancer Cell Lines
Authors: Guo Sheng , Qian Wubin , Cai Jie , Zhang Likun , Wery Jean-Pierre , Li Qi-Xiang
Published: April 2023

Figure S1. Comparison of gene expression within and between cancer types when the number of pairwise DEGs is 3000.
Supplementary Figures S1-S13 from Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells
Authors: Tang Chih-Hang Anthony , Zundell Joseph A. , Ranatunga Sujeewa , Lin Cindy , Nefedova Yulia , Del Valle Juan R. , Hu Chih-Chi Andrew
Published: April 2023

STING co-immunoprecipitates with IRE-1 (S1); Chemical structures of STING agonists (S2); Analysis of 3'3'-cGAMP by RP-HPLC and NMR (S3); STING does not undergo N-linked glycosylation before and after stimulations by 3'3'-cGAMP (S4); Deletion of mouse STING gene by ZFN (S5); STING-null A20 cells are resistant to 3'3'-cGAMP-induced apoptosis (S6); Tandem MS spectra of phosphorylated S357 and S365 peptides of mouse STING (S7); The affinity-purified anti-STING antibody specifically immunostains mouse STING in 5TGM1 myeloma cells (S8); An IRE-1/XBP-1 pathway inhibitor, B-I09, enhances the cytotoxicity of 3'3'-cGAMP in normal and malignant B cells (S9); STING agonists do not induce apoptosis, but elicit phosphorylation of IRF3 and STAT1 in melanoma, hepatoma, and Lewis lung cancer cells (S10); STING agonists do not induce apoptosis in normal T cells (S11); STING-deficient 5TGM1 and A20 cells respond normally to ER stress inducers, and exhibit normal intracellular transport of class I MHC molecules (S12); 5TGM1 myeloma cells grafted subcutaneously in immunodeficient NSG mice do not migrate to bone marrow, peripheral blood and spleens (S13).
Table S4 from Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer
Authors: Bhat-Nakshatri Poornima , Goswami Chirayu P. , Badve Sunil , Magnani Luca , Lupien Mathieu , Nakshatri Harikrishna
Published: April 2023

AKT1-AKT2_FOXA1_Comparison gene: FOXA1:E2 dependent genes are preferentially associated with AKT1
Supplementary Figure S9 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

A possible binding site for AIMP2 in the Smurf2 HECT domain.
Table S3 from Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer
Authors: Bhat-Nakshatri Poornima , Goswami Chirayu P. , Badve Sunil , Magnani Luca , Lupien Mathieu , Nakshatri Harikrishna
Published: April 2023

AKT1 and AKT2-specific E2-regulated genes
Table S2 from Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer
Authors: Bhat-Nakshatri Poornima , Goswami Chirayu P. , Badve Sunil , Magnani Luca , Lupien Mathieu , Nakshatri Harikrishna
Published: April 2023

Microarray results of E2 regulated genes in three cell types
Supplementary Figure S7 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

Effect of AIMP2 phosphorylation on its molecular interactions.
Supplementary methods, legends and Table S1 from Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer
Authors: Bhat-Nakshatri Poornima , Goswami Chirayu P. , Badve Sunil , Magnani Luca , Lupien Mathieu , Nakshatri Harikrishna
Published: April 2023

Additional methods, supplementary figure legend and Table S1
Figure S3 from Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer
Authors: Bhat-Nakshatri Poornima , Goswami Chirayu P. , Badve Sunil , Magnani Luca , Lupien Mathieu , Nakshatri Harikrishna
Published: April 2023

Prognostic value of FOXA1-AKT1-ER signature in additional datasets
Supplementary Figure S5 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

Identification of TGF-β1-induced phosphorylation site in AIMP2.
Figure S1 from Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer
Authors: Bhat-Nakshatri Poornima , Goswami Chirayu P. , Badve Sunil , Magnani Luca , Lupien Mathieu , Nakshatri Harikrishna
Published: April 2023

Ingenuity pathway analyses of E2-regulated genes dependent on AKT1
Supplementary Figure S1 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

Determination of the peptide regions responsible for the interaction between Smurf2 and AIMP2.
Figure S4 from A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
Authors: Hubert Christopher G. , Rivera Maricruz , Spangler Lisa C. , Wu Qiulian , Mack Stephen C. , Prager Briana C. , Couce Marta , McLendon Roger E. , Sloan Andrew E. , Rich Jeremy N.
Published: April 2023

SOX2 and OLIG2 expression in spheres and organoids.
Supplementary Figure Legend and References from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

Legend for Supplementary Figures S1-S11. Also includes Supplementary References.
Figure S3 from A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
Authors: Hubert Christopher G. , Rivera Maricruz , Spangler Lisa C. , Wu Qiulian , Mack Stephen C. , Prager Briana C. , Couce Marta , McLendon Roger E. , Sloan Andrew E. , Rich Jeremy N.
Published: April 2023

Organoid stem cell gradients are stable over time.
Supplementary Table S2 from Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP
Authors: Hatzl Stefan , Geiger Olivia , Kuepper Maja Kim , Caraffini Veronica , Seime Till , Furlan Tobias , Nussbaumer Erika , Wieser Rotraud , Pichler Martin , Scheideler Marcel , Nowek Katarzyna , Jongen-Lavrencic Mojca , Quehenberger Franz , Wölfler Albert , Troppmair Jakob , Sill Heinz , Zebisch Armin
Published: April 2023

Datasets downloaded from TCGA.
Supplementary Figure S5 from Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP
Authors: Hatzl Stefan , Geiger Olivia , Kuepper Maja Kim , Caraffini Veronica , Seime Till , Furlan Tobias , Nussbaumer Erika , Wieser Rotraud , Pichler Martin , Scheideler Marcel , Nowek Katarzyna , Jongen-Lavrencic Mojca , Quehenberger Franz , Wölfler Albert , Troppmair Jakob , Sill Heinz , Zebisch Armin
Published: April 2023

RKIP 3'UTR contains predicted miR-23a binding site(s).
Supplemental Figure 7 from Nucleolin Promotes Heat Shock–Associated Translation of VEGF-D to Promote Tumor Lymphangiogenesis
Authors: Morfoisse Florent , Tatin Florence , Hantelys Fransky , Adoue Aurelien , Helfer Anne-Catherine , Cassant-Sourdy Stephanie , Pujol Françoise , Gomez-Brouchet Anne , Ligat Laetitia , Lopez Frederic , Pyronnet Stephane , Courty Jose , Guillermet-Guibert Julie , Marzi Stefano , Schneider Robert J. , Prats Anne-Catherine , Garmy-Susini Barbara H.
Published: April 2023

Figure S7. Tumor growth after NSAID treatment
Supplementary Figure Legends from Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells
Authors: Timosenko Elina , Ghadbane Hemza , Silk Jonathan D. , Shepherd Dawn , Gileadi Uzi , Howson Lauren J. , Laynes Robert , Zhao Qi , Strausberg Robert L. , Olsen Lars R. , Taylor Stephen , Buffa Francesca M. , Boyd Richard , Cerundolo Vincenzo
Published: April 2023

Legends for supplementary figures.
Supplemental Figure 1 from Nucleolin Promotes Heat Shock–Associated Translation of VEGF-D to Promote Tumor Lymphangiogenesis
Authors: Morfoisse Florent , Tatin Florence , Hantelys Fransky , Adoue Aurelien , Helfer Anne-Catherine , Cassant-Sourdy Stephanie , Pujol Françoise , Gomez-Brouchet Anne , Ligat Laetitia , Lopez Frederic , Pyronnet Stephane , Courty Jose , Guillermet-Guibert Julie , Marzi Stefano , Schneider Robert J. , Prats Anne-Catherine , Garmy-Susini Barbara H.
Published: April 2023

Figure S1. Method to quantify lymphatic vessels diameter
Supplementary Table S3: from Cancer Therapy Directed by Comprehensive Genomic Profiling: A Single Center Study
Authors: Wheler Jennifer J. , Janku Filip , Naing Aung , Li Yali , Stephen Bettzy , Zinner Ralph , Subbiah Vivek , Fu Siqing , Karp Daniel , Falchook Gerald S. , Tsimberidou Apostolia M. , Piha-Paul Sarina , Anderson Roosevelt , Ke Danxia , Miller Vincent , Yelensky Roman , Lee J. Jack , Hong David S. , Kurzrock Razelle
Published: April 2023

List of genes and matched drugs
Supplemental Table 2 from Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression
Authors: Marsh Timothy , Wong Irene , Sceneay Jaclyn , Barakat Amey , Qin Yuanbo , Sjödin Andreas , Alspach Elise , Nilsson Björn , Stewart Sheila A. , McAllister Sandra S.
Published: April 2023

Gene set enrichment analyses showing effects of age on tumor-promoting BMCs
Supplemental Table 1 from Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression
Authors: Marsh Timothy , Wong Irene , Sceneay Jaclyn , Barakat Amey , Qin Yuanbo , Sjödin Andreas , Alspach Elise , Nilsson Björn , Stewart Sheila A. , McAllister Sandra S.
Published: April 2023

Gene set enrichment analyses showing effects of TNBC on tumor-promoting BMCs of young and old mice
supplemental material from The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial–Mesenchymal Transition in Breast Cancer
Authors: Latorre Elisa , Carelli Stephana , Raimondi Ivan , D'Agostino Vito , Castiglioni Ilaria , Zucal Chiara , Moro Giacomina , Luciani Andrea , Ghilardi Giorgio , Monti Eleonora , Inga Alberto , Di Giulio Anna Maria , Gorio Alfredo , Provenzani Alessandro
Published: April 2023

Primers used in PCR reactions. Gene silencing and over-expression tools.
supplemental figure 4 from The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial–Mesenchymal Transition in Breast Cancer
Authors: Latorre Elisa , Carelli Stephana , Raimondi Ivan , D'Agostino Vito , Castiglioni Ilaria , Zucal Chiara , Moro Giacomina , Luciani Andrea , Ghilardi Giorgio , Monti Eleonora , Inga Alberto , Di Giulio Anna Maria , Gorio Alfredo , Provenzani Alessandro
Published: April 2023

Rescue of phenotype by CD133 silencing in HuR KD cells and assessment of HuR binding to CD133 mRNA.
Supplementary Table 2 from The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast Cancer
Authors: Ekambaram Prasanna , Lee Jia-Ying (Lloyd) , Hubel Nathaniel E. , Hu Dong , Yerneni Saigopalakrishna , Campbell Phil G. , Pollock Netanya , Klei Linda R. , Concel Vincent J. , Delekta Phillip C. , Chinnaiyan Arul M. , Tomlins Scott A. , Rhodes Daniel R. , Priedigkeit Nolan , Lee Adrian V. , Oesterreich Steffi , McAllister-Lucas Linda M. , Lucas Peter C.
Published: April 2023

Candidate pro-angiogenic factors secreted from Ang II-stimulated AGTR1+ breast cancer cells.
Supplementary Figure S4 from The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast Cancer
Authors: Ekambaram Prasanna , Lee Jia-Ying (Lloyd) , Hubel Nathaniel E. , Hu Dong , Yerneni Saigopalakrishna , Campbell Phil G. , Pollock Netanya , Klei Linda R. , Concel Vincent J. , Delekta Phillip C. , Chinnaiyan Arul M. , Tomlins Scott A. , Rhodes Daniel R. , Priedigkeit Nolan , Lee Adrian V. , Oesterreich Steffi , McAllister-Lucas Linda M. , Lucas Peter C.
Published: April 2023

Role of CARMA3 and MALT1 in mediating 2D proliferation and 3D spheroid growth.
Supplementary Figure S3 from The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast Cancer
Authors: Ekambaram Prasanna , Lee Jia-Ying (Lloyd) , Hubel Nathaniel E. , Hu Dong , Yerneni Saigopalakrishna , Campbell Phil G. , Pollock Netanya , Klei Linda R. , Concel Vincent J. , Delekta Phillip C. , Chinnaiyan Arul M. , Tomlins Scott A. , Rhodes Daniel R. , Priedigkeit Nolan , Lee Adrian V. , Oesterreich Steffi , McAllister-Lucas Linda M. , Lucas Peter C.
Published: April 2023

Ang II-dependant activation on NFkB in additional AGTR1+ breast cancer cell lines (Hs578T and Hs606T).
Supplemental Material and Methods from Noninvasive In Vivo Imaging and Biologic Characterization of Thyroid Tumors by ImmunoPET Targeting of Galectin-3
Authors: D'Alessandria Calogero , Braesch-Andersen Sten , Bejo Kristel , Reder Sybille , Blechert Birgit , Schwaiger Markus , Bartolazzi Armando
Published: April 2023

Description of additional methods and procedures used in the study.
Figure S2 from Noninvasive In Vivo Imaging and Biologic Characterization of Thyroid Tumors by ImmunoPET Targeting of Galectin-3
Authors: D'Alessandria Calogero , Braesch-Andersen Sten , Bejo Kristel , Reder Sybille , Blechert Birgit , Schwaiger Markus , Bartolazzi Armando
Published: April 2023

Immunohistochemical analysis of galectin-3 expression in normal tissues ex vivo.
Supp Figure Legends from Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia
Authors: Bachegowda Lohith , Morrone Kerry , Winski Shannon L. , Mantzaris Ioannis , Bartenstein Matthias , Ramachandra Nandini , Giricz Orsi , Sukrithan Vineeth , Nwankwo George , Shahnaz Samira , Bhagat Tushar D. , Bhattacharyya Sanchari , Assal Amer , Shastri Aditi , Gordon-Mitchell Shanisha , Pellagatti Andrea , Boultwood Jacqueline , Schinke Carolina , Yu Yiting , Guha Chandan , Rizzi James , Garrus Jennifer , Brown Suzy , Wollenberg Lance , Hogeland Grant , Wright Dale , Munson Mark , Rodriguez Mareli , Gross Stefan , Chantry David , Zou Yiyu , Platanias Leonidas C. , Burgess Laurence E. , Pradhan Kith , Steidl Ulrich , Verma Amit
Published: April 2023

Supp Fig 1-3 Legends
Supplementary Figures S1-S5 from Multivalent Peptoid Conjugates Which Overcome Enzalutamide Resistance in Prostate Cancer Cells
Authors: Wang Yu , Dehigaspitiya Dilani C. , Levine Paul M. , Profit Adam A. , Haugbro Michael , Imberg-Kazdan Keren , Logan Susan K. , Kirshenbaum Kent , Garabedian Michael J.
Published: April 2023

MPC6 inhibits AR transcriptional activity (S1); MPC6 treatment did not decrease AR protein level in prostate cancer cell lines (S2); MPC6's anti-proliferative effect in non-prostate cancer cell lines (S3); PK/PD analysis for plasma MPC6 concentration (S4); MPC6 treatment did not significantly reduce host body weight (S5).
Supplementary tables 1-9 from Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma
Authors: Dawkins Joshua B.N. , Wang Jun , Maniati Eleni , Heward James A. , Koniali Lola , Kocher Hemant M. , Martin Sarah A. , Chelala Claude , Balkwill Frances R. , Fitzgibbon Jude , Grose Richard P.
Published: April 2023

Tables containing supplemental data for Table S1 to Table S9
Legends for Supplemental Figures and Tables from Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma
Authors: Dawkins Joshua B.N. , Wang Jun , Maniati Eleni , Heward James A. , Koniali Lola , Kocher Hemant M. , Martin Sarah A. , Chelala Claude , Balkwill Frances R. , Fitzgibbon Jude , Grose Richard P.
Published: April 2023

Document containing the supplemental figure and supplemental table legends
Supplementary TABLE 2 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity
Authors: Ricklefs Franz , Mineo Marco , Rooj Arun K. , Nakano Ichiro , Charest Al , Weissleder Ralph , Breakefield Xandra O. , Chiocca E. Antonio , Godlewski Jakub , Bronisz Agnieszka
Published: April 2023

Genes coding for protein sets that vary coherently between GSC subtypes within 89- protein signature, were retrieved from TCGA GBM dataset and identified by subtype prediction.
Figure S6 from Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma
Authors: Dawkins Joshua B.N. , Wang Jun , Maniati Eleni , Heward James A. , Koniali Lola , Kocher Hemant M. , Martin Sarah A. , Chelala Claude , Balkwill Frances R. , Fitzgibbon Jude , Grose Richard P.
Published: April 2023

Depletion of Kmt2d and Kmt2c does not affect the viability of murine pancreatic cancer cells, and Kmt2c depletion does not affect sensitivity to 5FU.
Supplementary TABLE 1 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity
Authors: Ricklefs Franz , Mineo Marco , Rooj Arun K. , Nakano Ichiro , Charest Al , Weissleder Ralph , Breakefield Xandra O. , Chiocca E. Antonio , Godlewski Jakub , Bronisz Agnieszka
Published: April 2023

List of the 89 proteins from GSC EV proteome profile distinguishing P from M GSC subtypes; signal intensity
Figure S5 from Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma
Authors: Dawkins Joshua B.N. , Wang Jun , Maniati Eleni , Heward James A. , Koniali Lola , Kocher Hemant M. , Martin Sarah A. , Chelala Claude , Balkwill Frances R. , Fitzgibbon Jude , Grose Richard P.
Published: April 2023

Correlations of gene expression and patient survival.
Supplementary Methods from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity
Authors: Ricklefs Franz , Mineo Marco , Rooj Arun K. , Nakano Ichiro , Charest Al , Weissleder Ralph , Breakefield Xandra O. , Chiocca E. Antonio , Godlewski Jakub , Bronisz Agnieszka
Published: April 2023

Supplementary material and methods
Supplementary Figure Legend from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity
Authors: Ricklefs Franz , Mineo Marco , Rooj Arun K. , Nakano Ichiro , Charest Al , Weissleder Ralph , Breakefield Xandra O. , Chiocca E. Antonio , Godlewski Jakub , Bronisz Agnieszka
Published: April 2023

Figure Legend to all supplementary data
Supplementary Figure 4 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity
Authors: Ricklefs Franz , Mineo Marco , Rooj Arun K. , Nakano Ichiro , Charest Al , Weissleder Ralph , Breakefield Xandra O. , Chiocca E. Antonio , Godlewski Jakub , Bronisz Agnieszka
Published: April 2023

Supplementary Figure 4 related to Figure 4. GSC EV proteome predicts patients' outcome
Supplementary Figure 3 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity
Authors: Ricklefs Franz , Mineo Marco , Rooj Arun K. , Nakano Ichiro , Charest Al , Weissleder Ralph , Breakefield Xandra O. , Chiocca E. Antonio , Godlewski Jakub , Bronisz Agnieszka
Published: April 2023

Supplementary Figure 3 related to Figure 3. Presence of P GSC supports pro-oncogenic traits of M GSCs in vivo
Supplementary Figure 2 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity
Authors: Ricklefs Franz , Mineo Marco , Rooj Arun K. , Nakano Ichiro , Charest Al , Weissleder Ralph , Breakefield Xandra O. , Chiocca E. Antonio , Godlewski Jakub , Bronisz Agnieszka
Published: April 2023

Supplementary Figure 2 related to Figure 2. Presence of EVM supports pro-oncogenic traits of P GSCs in vitro.
Supplementary Materials and Methods from Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer
Authors: Herrera-Abreu Maria Teresa , Palafox Marta , Asghar Uzma , Rivas Martín A. , Cutts Rosalind J. , Garcia-Murillas Isaac , Pearson Alex , Guzman Marta , Rodriguez Olga , Grueso Judit , Bellet Meritxell , Cortés Javier , Elliott Richard , Pancholi Sunil , Lord Christopher J. , Baselga José , Dowsett Mitch , Martin Lesley-Ann , Turner Nicholas C. , Serra Violeta
Published: April 2023

Supplementary Materials and Methods
Supplementary Figures 1 through 7 from Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer
Authors: Herrera-Abreu Maria Teresa , Palafox Marta , Asghar Uzma , Rivas Martín A. , Cutts Rosalind J. , Garcia-Murillas Isaac , Pearson Alex , Guzman Marta , Rodriguez Olga , Grueso Judit , Bellet Meritxell , Cortés Javier , Elliott Richard , Pancholi Sunil , Lord Christopher J. , Baselga José , Dowsett Mitch , Martin Lesley-Ann , Turner Nicholas C. , Serra Violeta
Published: April 2023

Supplementary Figure 1: Early adaptive resistance limits the efficacy of CDK4/6 inhibition. High-throughput drug screen identified PI3K-mTOR inhibitors as sensitizers to CDK4/6 inhibitors. Supplementary Figure 2: Determinants of sensitivity to the combination CDK4/6 and PI3K inhibition. Supplementary Figure 3: Early adaptation to CDK4/6 inhibition is mediated by non-canonical cyclin D1-CDK2 interaction. IGF1R inhibition increases sensitivity to CDK4/6 inhibition in MCF-7 cells. Supplementary Figure 4: Palbociclib induced senescence like morphology is reversible. Supplementary Figure 5: Acquired palbociclib resistance through RB1 loss or CCNE1 amplification/expression. Supplementary Figure 6: Body weight of mice during vehicle, BYL719, LEE011 or combination treatment. Supplementary Figure 7: The combination LEE011 and BYL719 is more effective in ER positive PDX than single agent treatments.
Supplementary Figures S1-S2 from Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones
Authors: Ren Yi A. , Mullany Lisa K. , Liu Zhilin , Herron Alan J. , Wong Kwong-Kwok , Richards JoAnne S.
Published: April 2023

Sequencing results of laser capture microdissected human mucinous tumor cells (S1); Representative images of immunofluorescent staining for ESR1 and PGR in cultured tumor OSE cells of different genetic background (S2).
Supplementary Figure Legends from Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer
Authors: Herrera-Abreu Maria Teresa , Palafox Marta , Asghar Uzma , Rivas Martín A. , Cutts Rosalind J. , Garcia-Murillas Isaac , Pearson Alex , Guzman Marta , Rodriguez Olga , Grueso Judit , Bellet Meritxell , Cortés Javier , Elliott Richard , Pancholi Sunil , Lord Christopher J. , Baselga José , Dowsett Mitch , Martin Lesley-Ann , Turner Nicholas C. , Serra Violeta
Published: April 2023

Supplementary Figure Legends
Supplementary table from Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer
Authors: Lazar Ikrame , Clement Emily , Dauvillier Stéphanie , Milhas Delphine , Ducoux-Petit Manuelle , LeGonidec Sophie , Moro Cédric , Soldan Vanessa , Dalle Stéphane , Balor Stéphanie , Golzio Muriel , Burlet-Schiltz Odile , Valet Philippe , Muller Catherine , Nieto Laurence
Published: April 2023

Proteins identified by mass-spectrometry in adipocyte exosomes
Supplementary Table 1 and Supplementary Figures 1 through 6 from CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma
Authors: Feber Andrew , Worth Daniel C. , Chakravarthy Ankur , de Winter Patricia , Shah Kunal , Arya Manit , Saqib Muhammad , Nigam Raj , Malone Peter R. , Tan Wei Shen , Rodney Simon , Freeman Alex , Jameson Charles , Wilson Gareth A. , Powles Tom , Beck Stephan , Fenton Tim , Sharp Tyson V. , Muneer Asif , Kelly John D.
Published: April 2023

Supplementary Table 1. A)Patient details for Fresh Frozen test cohort, B) Patient details for validation cohort. Supplementary Figure 1. APOBEC mutation fraction of across multiple cancer types. Supplementary Figure 2. DNA methylation. Supplementary Figure 3. Candidate PeCa driver mutations. Supplementary Figure 4. Schematic of FAT1 is shown with locations of mutations and ethylation states of PeCa and normal penile tissue across the canonical FAT1 gene. Supplementary Figure 5. A) Example plot of Copy Number Alterations (CNA) in penile cancers, 450K methylation profiles for penile cancer and normal squamous epithelium, and output from GISTIC showing the frequency and significance of CNAs.
Supplemental Figure S4 from Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss
Authors: Jolly Lee Ann , Novitskiy Sergey , Owens Phillip , Massoll Nicole , Cheng Nikki , Fang Wei , Moses Harold L. , Franco Aime T.
Published: April 2023

Supplemental Figure S4 Representative tracks of distance Hras and Braf-driven tumor cells travel over 4 hours.
Supplemental Figure S1 from Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss
Authors: Jolly Lee Ann , Novitskiy Sergey , Owens Phillip , Massoll Nicole , Cheng Nikki , Fang Wei , Moses Harold L. , Franco Aime T.
Published: April 2023

Supplemental Figure S1 Braf conditioned media induces CAF proliferation and migration.
supplemental materials and methods from Acetylcarnitine Is a Candidate Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma
Authors: Lu Yonghai , Li Ning , Gao Liang , Xu Yong-Jiang , Huang Chong , Yu Kangkang , Ling Qingxia , Cheng Qi , Chen Shengsen , Zhu Mengqi , Fang Jinling , Chen Mingquan , Ong Choon Nam
Published: April 2023

Quantitative analysis of acetylcarnitine in additional 58 serum samples.
Supplemental Figure Legends from Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss
Authors: Jolly Lee Ann , Novitskiy Sergey , Owens Phillip , Massoll Nicole , Cheng Nikki , Fang Wei , Moses Harold L. , Franco Aime T.
Published: April 2023

Legends for Supplemental Figures S1-S4
Supplementary Table 1 from Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non–Small Cell Lung Cancer
Authors: Lantermann Alexandra B. , Chen Dongshu , McCutcheon Kaitlin , Hoffman Greg , Frias Elizabeth , Ruddy David , Rakiec Daniel , Korn Joshua , McAllister Gregory , Stegmeier Frank , Meyer Matthew J. , Sharma Sreenath V.
Published: April 2023

Supplementary Table 1: Hit list shRNA screen
Supplementary Table and Figure Legend from An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells
Authors: Peitzsch Claudia , Cojoc Monica , Hein Linda , Kurth Ina , Mäbert Katrin , Trautmann Franziska , Klink Barbara , Schröck Evelin , Wirth Manfred P. , Krause Mechthild , Stakhovsky Eduard A. , Telegeev Gennady D. , Novotny Vladimir , Toma Marieta , Muders Michael , Baretton Gustavo B. , Frame Fiona M. , Maitland Norman J. , Baumann Michael , Dubrovska Anna
Published: April 2023

Legend for Supplementary Tables S1-S5 and Supplementary Figures S1-S10.
Supplementary Figures from Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non–Small Cell Lung Cancer
Authors: Lantermann Alexandra B. , Chen Dongshu , McCutcheon Kaitlin , Hoffman Greg , Frias Elizabeth , Ruddy David , Rakiec Daniel , Korn Joshua , McAllister Gregory , Stegmeier Frank , Meyer Matthew J. , Sharma Sreenath V.
Published: April 2023

Fig. S1. Summary of EGFR status and sensitivity to erlotinib of NSCLC cell lines used in this study. Fig. S2. Knockdown of CK1α inhibits proliferation of PC9 cells more than proliferation of HCC827 or HCC4006 cells under DMSO treatment. Fig. S3. Performance of individual shRNAs against members of the CK1-family in shRNA screens. Fig. S4. Knockdown of CK1α does not sensitize NSCLC cells to doxorubicin or cisplatin. Fig. S5. Suppression of CK1α attenuates acquired resistance to erlotinib in EGFR-mutant NSCLC cells. Fig. S6. Suppression of CK1α attenuates the outgrowth of drug tolerant persisters (DTPs) to resistant clones and inhibits proliferation of resistant PC9 cells in the presence of erlotinib. Fig. S7. The CK1 inhibitor D4476 can attenuate acquired resistance to erlotinib in NSCLC cell lines. Fig. S8: Knockdown of CK1α does not influence EGFR signaling. Fig. S9: Knockdown of CK1α does not activate WNT-signaling. Fig. S10: Erlotinib treatment activates NF-κB-signaling and CK1α-knockdown decreases expression of NF-κB-target genes. Fig. S11: Inhibition of NF-κB-signaling attenuates resistance to erlotinib while only slightly affecting proliferation in the absence of erlotinib.
Supplementary Figure Legends from Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non–Small Cell Lung Cancer
Authors: Lantermann Alexandra B. , Chen Dongshu , McCutcheon Kaitlin , Hoffman Greg , Frias Elizabeth , Ruddy David , Rakiec Daniel , Korn Joshua , McAllister Gregory , Stegmeier Frank , Meyer Matthew J. , Sharma Sreenath V.
Published: April 2023

Supplementary Figure Legends 1-11 Lantermann et al.
Supplemental Table 5 from Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk
Authors: Patel Yesha M. , Park Sunghim L. , Han Younghun , Wilkens Lynne R. , Bickeböller Heike , Rosenberger Albert , Caporaso Neil , Landi Maria Teresa , Brüske Irene , Risch Angela , Wei Yongyue , Christiani David C. , Brennan Paul , Houlston Richard , McKay James , McLaughlin John , Hung Rayjean , Murphy Sharon , Stram Daniel O. , Amos Christopher , Le Marchand Loïc
Published: April 2023

LD between nine functional CYP2A6 variants and top six overlapping associations between MEC & TRICL - among Whites and Overall MEC sample
Supplemental Table 4 from Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk
Authors: Patel Yesha M. , Park Sunghim L. , Han Younghun , Wilkens Lynne R. , Bickeböller Heike , Rosenberger Albert , Caporaso Neil , Landi Maria Teresa , Brüske Irene , Risch Angela , Wei Yongyue , Christiani David C. , Brennan Paul , Houlston Richard , McKay James , McLaughlin John , Hung Rayjean , Murphy Sharon , Stram Daniel O. , Amos Christopher , Le Marchand Loïc
Published: April 2023

Results of the six overlapping globally significant associations (p < 5E-8) with lung cancer risk in TRICL and with CYP2A6 activtiy in MEC stratified by cell type.
Supplementary Table S1 from An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells
Authors: Peitzsch Claudia , Cojoc Monica , Hein Linda , Kurth Ina , Mäbert Katrin , Trautmann Franziska , Klink Barbara , Schröck Evelin , Wirth Manfred P. , Krause Mechthild , Stakhovsky Eduard A. , Telegeev Gennady D. , Novotny Vladimir , Toma Marieta , Muders Michael , Baretton Gustavo B. , Frame Fiona M. , Maitland Norman J. , Baumann Michael , Dubrovska Anna
Published: April 2023

Regulation of the genes that were not mapped within the deleted or amplified chromosomal regions in the entire population of DU145 parental (P) cells versus DU145 radioresistant (RR) cells.
Supplemental Table 3 from Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk
Authors: Patel Yesha M. , Park Sunghim L. , Han Younghun , Wilkens Lynne R. , Bickeböller Heike , Rosenberger Albert , Caporaso Neil , Landi Maria Teresa , Brüske Irene , Risch Angela , Wei Yongyue , Christiani David C. , Brennan Paul , Houlston Richard , McKay James , McLaughlin John , Hung Rayjean , Murphy Sharon , Stram Daniel O. , Amos Christopher , Le Marchand Loïc
Published: April 2023

Descriptive Characteristics of TRICL participants
Supplemental Table 2 from Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk
Authors: Patel Yesha M. , Park Sunghim L. , Han Younghun , Wilkens Lynne R. , Bickeböller Heike , Rosenberger Albert , Caporaso Neil , Landi Maria Teresa , Brüske Irene , Risch Angela , Wei Yongyue , Christiani David C. , Brennan Paul , Houlston Richard , McKay James , McLaughlin John , Hung Rayjean , Murphy Sharon , Stram Daniel O. , Amos Christopher , Le Marchand Loïc
Published: April 2023

List of 226 overlapping associations for CYP2A6 in the TRICL & MEC Studies
Supplementary Figures S1-S10 from An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells
Authors: Peitzsch Claudia , Cojoc Monica , Hein Linda , Kurth Ina , Mäbert Katrin , Trautmann Franziska , Klink Barbara , Schröck Evelin , Wirth Manfred P. , Krause Mechthild , Stakhovsky Eduard A. , Telegeev Gennady D. , Novotny Vladimir , Toma Marieta , Muders Michael , Baretton Gustavo B. , Frame Fiona M. , Maitland Norman J. , Baumann Michael , Dubrovska Anna
Published: April 2023

Irradiation-induced changes in the expression of stem cell markers (S1); Genetic alterations in the irradiated prostate cancer cells (S2); Regulation of histone methylation in response to cell irradiation (S3); Differential expression of stem cell and EMT markers in response to irradiation in the parental and radioresistant prostate cancer cells (S4); The role of ALDH1A1 expression in regulation of spherogenicity, tumorigenicity and radioresistance of the parental and radioresistant prostate cancer cells (S5); Analysis and validation of the global gene expression data (S6); Analysis of cell viability, plating efficacy and post-irradiation clonogenic survival in response to inhibition of the histone methylation activity (S7); Effect of DZNep treatment on apoptosis induction and γH2A.X level in prostate cancer cell lines (S8); Analysis of apoptosis induction and γH2A.X increase by DZNep treatment in prostate tumor tissues and primary cell cultures (S9); Co-regulation of EZH2, ALDH1A1 and CTNNB1 in cell lines and prostate tumors (S10).
Supplementary Materials and Methods from Feasibility of Telomerase-Specific Adoptive T-cell Therapy for B-cell Chronic Lymphocytic Leukemia and Solid Malignancies
Authors: Sandri Sara , Bobisse Sara , Moxley Kelly , Lamolinara Alessia , De Sanctis Francesco , Boschi Federico , Sbarbati Andrea , Fracasso Giulio , Ferrarini Giovanna , Hendriks Rudi W. , Cavallini Chiara , Scupoli Maria Teresa , Sartoris Silvia , Iezzi Manuela , Nishimura Michael I. , Bronte Vincenzo , Ugel Stefano
Published: April 2023

Supplementary Materials and Methods
Supplementary Table-3 from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Supplemental Table 3. Sequences of the primers used for qRT-PCR
Supplementary Table-2 from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Supplemental Table 2. Sequences of the shRNA vectors
Supplementary Figure Legends from Feasibility of Telomerase-Specific Adoptive T-cell Therapy for B-cell Chronic Lymphocytic Leukemia and Solid Malignancies
Authors: Sandri Sara , Bobisse Sara , Moxley Kelly , Lamolinara Alessia , De Sanctis Francesco , Boschi Federico , Sbarbati Andrea , Fracasso Giulio , Ferrarini Giovanna , Hendriks Rudi W. , Cavallini Chiara , Scupoli Maria Teresa , Sartoris Silvia , Iezzi Manuela , Nishimura Michael I. , Bronte Vincenzo , Ugel Stefano
Published: April 2023

Supplementary Figure Legends for Supplemental Figures 1-5
Supplementary Method from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Supplementary method
Supplementary Materials and Methods from Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody
Authors: Pupo Emanuela , Ducano Nadia , Lupo Barbara , Vigna Elisa , Avanzato Daniele , Perera Timothy , Trusolino Livio , Lanzetti Letizia , Comoglio Paolo M.
Published: April 2023

Description of antibodies, growth factors and chemicals, immunofluorescence endocytosis assay, HGF labeling, in vivo experiment of Supplementary Figure S6
Supplementary Figure S6 from Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody
Authors: Pupo Emanuela , Ducano Nadia , Lupo Barbara , Vigna Elisa , Avanzato Daniele , Perera Timothy , Trusolino Livio , Lanzetti Letizia , Comoglio Paolo M.
Published: April 2023

In vivo rebound MET activation
Supplemental Tables S1-S3 from Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy
Authors: Shaked Yuval , Pham Elizabeth , Hariharan Santosh , Magidey Ksenia , Beyar-Katz Ofrat , Xu Ping , Man Shan , Wu Florence T.H. , Miller Valeria , Andrews David , Kerbel Robert S.
Published: April 2023

Panel of antibodies used for the mass cytometry assay (S1); Surface markers associated with metastasis (S2); Features extracted for each colony (S3).
Supplementary Figure S2 from Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody
Authors: Pupo Emanuela , Ducano Nadia , Lupo Barbara , Vigna Elisa , Avanzato Daniele , Perera Timothy , Trusolino Livio , Lanzetti Letizia , Comoglio Paolo M.
Published: April 2023

JNJ-605 does not inhibit EGFR endocytosis
Supplemental Materials and Methods from Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy
Authors: Shaked Yuval , Pham Elizabeth , Hariharan Santosh , Magidey Ksenia , Beyar-Katz Ofrat , Xu Ping , Man Shan , Wu Florence T.H. , Miller Valeria , Andrews David , Kerbel Robert S.
Published: April 2023

Materials and Methods used in the supplemental information including flow cytometry, viable CEP levels, colony forming assay, and tissue immunostaining
Supplemental Figures S1-S6 from Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy
Authors: Shaked Yuval , Pham Elizabeth , Hariharan Santosh , Magidey Ksenia , Beyar-Katz Ofrat , Xu Ping , Man Shan , Wu Florence T.H. , Miller Valeria , Andrews David , Kerbel Robert S.
Published: April 2023

Levels of viable CEPs in the blood of Balb/c mice treated with escalating doses of capecitabine (S1); A flow chart of the image analysis (S2); Colonization of bone marrow derived cells in tumors from mice treated with LDM or MTD capecitabine regimens with or without LDM CTX assessed by flow cytometry (S3); Apoptosis and necrosis in tumors from mice treated with LDM or MTD capecitabine regimens with or without LDM CTX (S4); Microvessel density in tumors from mice treated with LDM or MTD capecitabine regimens with or without LDM CTX (S5); Liver metastasis in HT-29 bearing mice treated with MTD or LDM capecitabine regimens with or without LDM CTX (S6).
Supplementary Tables for BMI, WC and diabetes with risk of liver cancer from Body Mass Index, Waist Circumference, Diabetes, and Risk of Liver Cancer for U.S. Adults
Authors: Campbell Peter T. , Newton Christina C. , Freedman Neal D. , Koshiol Jill , Alavanja Michael C. , Beane Freeman Laura E. , Buring Julie E. , Chan Andrew T. , Chong Dawn Q. , Datta Mridul , Gaudet Mia M. , Gaziano J. Michael , Giovannucci Edward L. , Graubard Barry I. , Hollenbeck Albert R. , King Lindsey , Lee I.-Min , Linet Martha S. , Palmer Julie R. , Petrick Jessica L. , Poynter Jenny N. , Purdue Mark P. , Robien Kim , Rosenberg Lynn , Sahasrabuddhe Vikrant V. , Schairer Catherine , Sesso Howard D. , Sigurdson Alice J. , Stevens Victoria L. , Wactawski-Wende Jean , Zeleniuch-Jacquotte Anne , Renehan Andrew G. , McGlynn Katherine A.
Published: April 2023

Descriptive table or cohorts and results from sensitivity analyses
Supplementary Figure 2. Individual participant meta-analysis of waist circumference (per 5 cm) and liver cancer risk in the Liver Cancer Pooling Project from Body Mass Index, Waist Circumference, Diabetes, and Risk of Liver Cancer for U.S. Adults
Authors: Campbell Peter T. , Newton Christina C. , Freedman Neal D. , Koshiol Jill , Alavanja Michael C. , Beane Freeman Laura E. , Buring Julie E. , Chan Andrew T. , Chong Dawn Q. , Datta Mridul , Gaudet Mia M. , Gaziano J. Michael , Giovannucci Edward L. , Graubard Barry I. , Hollenbeck Albert R. , King Lindsey , Lee I.-Min , Linet Martha S. , Palmer Julie R. , Petrick Jessica L. , Poynter Jenny N. , Purdue Mark P. , Robien Kim , Rosenberg Lynn , Sahasrabuddhe Vikrant V. , Schairer Catherine , Sesso Howard D. , Sigurdson Alice J. , Stevens Victoria L. , Wactawski-Wende Jean , Zeleniuch-Jacquotte Anne , Renehan Andrew G. , McGlynn Katherine A.
Published: April 2023

Results from individual participant meta-analysis of WC. Footnote to Supplementary Figure 2. Multivariable models include age, sex, study, alcohol, smoking, race and body mass index. -
Nwani et al., Supplementary figures 1-11 from Melanoma Cells Block PEDF Production in Fibroblasts to Induce the Tumor-Promoting Phenotype of Cancer-Associated Fibroblasts
Authors: Nwani Nkechiyere G. , Deguiz Maria L. , Jimenez Benilde , Vinokour Elena , Dubrovskyi Oleksii , Ugolkov Andrey , Mazar Andrew P. , Volpert Olga V.
Published: April 2023

Supplemental Figure 1. Verification of PEDF knockdown Supplemental Figure 2. Verification of PEDF silencing in fibroblasts Supplemental Figure 3. The effect of PEDF expression in fibroblasts on tumor growth Supplemental Figure 4. The effect of endogenous PEDF on fibroblast proliferation and recruitment Supplemental Figure 5. The effect of exogenous TGFb and PDGF on PEDF mRNA in fibroblasts Supplemental Figure 6. The contribution of of TGFb and PDGF to PEDF repression assessed by shRNA silencing Supplemental Figure 7. The effect of TGFb on PDGFR mRNA levels Supplemental Figure 8. Regulation of PDGFB mRNA by TGFb Supplemental Figure 9. The role of PI3K in PEDF control by PDGF-BB Supplemental Figure 10. Inhibition of non-canonical TGFb signaling by PEDF Supplemental Figure 11. Altered expression of select genes in PEDF-null fibroblasts
Table S2 from CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma
Authors: Walton Josephine , Blagih Julianna , Ennis Darren , Leung Elaine , Dowson Suzanne , Farquharson Malcolm , Tookman Laura A. , Orange Clare , Athineos Dimitris , Mason Susan , Stevenson David , Blyth Karen , Strathdee Douglas , Balkwill Frances R. , Vousden Karen , Lockley Michelle , McNeish Iain A.
Published: April 2023

Summary of sequencing variant findings
Supplementary methods from CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma
Authors: Walton Josephine , Blagih Julianna , Ennis Darren , Leung Elaine , Dowson Suzanne , Farquharson Malcolm , Tookman Laura A. , Orange Clare , Athineos Dimitris , Mason Susan , Stevenson David , Blyth Karen , Strathdee Douglas , Balkwill Frances R. , Vousden Karen , Lockley Michelle , McNeish Iain A.
Published: April 2023

Full description of next generation sequencing, quantitative IHC and flow cytometry
Supplementary tables 1 and 2 from Resistance to Anti-VEGF Therapy Mediated by Autocrine IL6/STAT3 Signaling and Overcome by IL6 Blockade
Authors: Eichten Alexandra , Su Jia , Adler Alexander P. , Zhang Li , Ioffe Ella , Parveen Asma A. , Yancopoulos George D. , Rudge John , Lowy Israel , Lin Hsin Chieh , MacDonald Douglas , Daly Christopher , Duan Xunbao , Thurston Gavin
Published: April 2023

Supplementary tables 1 and 2
Supplementary Figure 6 from NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer–Initiating Cells
Authors: Srinivasan Tara , Walters Jewell , Bu Pengcheng , Than Elaine Bich , Tung Kuei-Ling , Chen Kai-Yuan , Panarelli Nicole , Milsom Jeff , Augenlicht Leonard , Lipkin Steven M. , Shen Xiling
Published: April 2023

BMI1+ and LGR5+ CCICs in xenograft tumors.
Supplementary Figures from In Vivo FRET Imaging of Tumor Endothelial Cells Highlights a Role of Low PKA Activity in Vascular Hyperpermeability
Authors: Yamauchi Fumio , Kamioka Yuji , Yano Tetsuya , Matsuda Michiyuki
Published: April 2023

Suppl. Figure 1: FRET biosensors detect protein kinase activities in vascular endothelial cells; Suppl. Figure 2: PKA biosensor specifically detects PKA activity; Suppl. Figure 3: Motesanib suppresses the activity of VEGFR2 in tumor endothelial cells in vivo; Suppl. Figure 4: VEGF activates ERK in tumor endothelial cells and HUVEC; Suppl. Figure 5: VEGF increases in cAMP level in HUVEC, but not Hela cells; Suppl. Figure 6: Endothelial cells isolated from subcutaneous tissues exhibit phenotypes similar to the endothelial cells in vivo;