bluuebunny/crossref_metadata_2025 huggingface dataset:
Iron-related Biomarkers in the Diagnosis and Management of Iron
Disorders
Authors: Semenova Yuliya , Bjørklund Geir , Butnariu Monica , Peana Massimiliano
Published: February 2024

Background:

Iron deficiency and iron-related disorders are common health issues
worldwide, affecting a significant proportion of the population. Diagnosis and management
of these disorders rely heavily on using various iron-related biomarkers that
can provide valuable clinical information.

Objective:

This review article provides an overview of the most commonly used iron-related
biomarkers, including serum ferritin, transferrin saturation, soluble transferrin receptor,
zinc protoporphyrin, and free erythrocyte protoporphyrin. Other emerging biomarkers,
such as hepcidin and retinol-binding protein 4, are also discussed.

Results:

Iron plays a vital role in various physiological processes, including oxygen transport,
energy metabolism, and DNA synthesis. The article highlights the advantages and
limitations of iron biomarkers and their clinical applications in diagnosing and managing
iron deficiency and iron-related anemia.

Conclusion:

Using iron-related biomarkers in screening and monitoring programs can
improve patient outcomes and reduce healthcare costs.
Evidence for the Involvement of Gene Regulation of Inflammatory Molecules in the Accumulation of Intracellular Cholesterol: The Mechanism
of Foam Cell Formation in Atherosclerosis
Authors: Sukhorukov Vasily N. , Khotina Victoria A. , Borodko Daria D. , Ekta Mariam Bagheri , Oishi Yumiko , Omelchenko Andrey V. , Kolmychkova Kira I. , Nikiforov Nikita G. , Sobenin Igor A. , Orekhov Alexander N.
Published: February 2024

Background:

The relationship between the cellular pro-inflammatory response
and intracellular lipid accumulation in atherosclerosis is not sufficiently studied.
Transcriptomic analysis is one way to establish such a relationship. Previously, we identified
10 potential key genes (IL-15, CXCL8, PERK, IL-7, IL-7R, DUSP1, TIGIT, F2RL1,
TSPYL2, and ANXA1) involved in cholesterol accumulation in macrophages. It
should be noted that all these genes do not directly participate in cholesterol
metabolism, but encode molecules related to inflammation.

Methods:

In this study, we conducted a knock-down of the 10 identified key genes using
siRNA to determine their possible role in cholesterol accumulation in macrophages.
To assess cholesterol accumulation, human monocyte-derived macrophages (MDM)
were incubated with atherogenic LDL from patients with atherosclerosis. Cholesterol
content was assessed by the enzymatic method. Differentially expressed genes were
identified with DESeq2 analysis. Master genes were determined by the functional analysis.

Results:

We found that only 5 out of 10 genes (IL-15, PERK, IL-7, IL-7R, ANXA1) can
affect intracellular lipid accumulation. Knock-down of the IL-15, PERK, and ANXA1
genes prevented lipid accumulation, while knock-down of the IL-7 and IL-7R genes led
to increased intracellular lipid accumulation during incubation of MDM with atherogenic
LDL. Seventeen overexpressed genes and 189 underexpressed genes were obtained
in the DGE analysis, which allowed us to discover 20 upregulated and 86 downregulated
metabolic pathways, a number of which are associated with chronic inflammation
and insulin signaling. We also elucidated 13 master regulators of cholesterol accumulation
that are immune response-associated genes.

Conclusion:

Thus, it was discovered that 5 inflammation-related master regulators may
be involved in lipid accumulation in macrophages. Therefore, the pro-inflammatory response
of macrophages may trigger foam cell formation rather than the other way
around, where intracellular lipid accumulation causes an inflammatory response, as previously
assumed.
The Future of Cystic Fibrosis Care: Exploring AI's Impact on Detection and Therapy
Authors: Basu Biswajit , Dutta Srabona , Rahaman Monosiz , Bose Anirbandeep , Das Sourav , Prajapati Jigna , Prajapati Bhupendra
Published: February 2024

:

Cystic Fibrosis (CF) is a fatal hereditary condition marked by thicker mucus production,
which can cause problems with the digestive and respiratory systems. The quality of life and
survival rates of CF patients can be improved by early identification and individualized therapy
measures. With an emphasis on its applications in diagnosis and therapy, this paper investigates
how Artificial Intelligence (AI) is transforming the management of Cystic Fibrosis (CF). AI-powered
algorithms are revolutionizing CF diagnosis by utilizing huge genetic, clinical, and imaging
data databases. In order to identify CF mutations quickly and precisely, machine learning methods
evaluate genomic profiles. Furthermore, AI-driven imaging analysis helps to identify lung and gastrointestinal
issues linked to cystic fibrosis early and allows for prompt treatment. Additionally,
AI aids in individualized CF therapy by anticipating how patients will react to already available
medications and enabling customized treatment regimens. Drug repurposing algorithms find
prospective candidates from already-approved drugs, advancing treatment choices. Additionally,
AI supports the optimization of pharmacological combinations, enhancing therapeutic results
while minimizing side effects. AI also helps with patient stratification by connecting people with
CF mutations to therapies that are best for their genetic profiles. Improved treatment effectiveness
is promised by this tailored strategy. The transformational potential of artificial intelligence (AI)
in the field of cystic fibrosis is highlighted in this review, from early identification to individualized
medication, bringing hope for better patient outcomes, and eventually prolonging the lives of
people with this difficult ailment.
Statin Therapy and Flow-Mediated Dilation: A Systematic Review and Dose-Response Meta-Analysis Using the GRADE of Data from Randomized Controlled Trials
Authors: Arabi Seyyed Mostafa , Chambari Mahla , Bahrami Leila Sadat , Hadi Saeid , Sahebkar Amirhossein
Published: February 2024

Introduction:

A previous meta-analysis reported the positive effects of statin therapy
on endothelial function. However, the obtained result had several limitations that necessitated updating
the information in this field. Therefore, a systematic and meta-analysis review was conducted
to determine whether statin therapy could improve endothelial function, as assessed by flow--
mediated dilation (FMD).

Methods:

MEDLINE, SciVerse Scopus, and Clarivate Analytics Web of Science were searched to
identify randomized placebo-controlled trials assessing the impact of statin therapy on FMD. A
random-effects model was used for meta-analysis to calculate the mean difference in weight. Meta-
regression and subgroup analyses were used to identify sources of heterogeneity. In addition,
nonlinear dose-response, quality of evidence, influence analysis, and publication bias evaluation
were assessed using standard methods.

Result:

Thirty-five trials (41 arms) involving 2178 participants were included in the meta-analysis
study. Statin treatment significantly improved FMD [weighted mean difference (WMD): 1.7%,
95% CI: 1.3-2.2, p < 0.001). However, significant heterogeneity was observed (I2=97.9%, p <
0.001). The results of the subgroup analysis showed that health status can contribute to heterogeneity.
Non-linear dose-response analysis revealed the most significant improvement in FMD with
atorvastatin at a dose of 20 mg/day and simvastatin at 80 mg/day.

Conclusion:

Statin therapy significantly improved endothelial function, as assessed by FMD. These
changes are clinically significant, but their use should be approached with caution.
Our Single Center Experience in Osteoid Osteoma Patients Treated with CTGuided Percutaneous Radiofrequency Ablation Treatment and Follow-up
Authors: Düzgün Fatih , Tosyalı Hakan Koray , Tarhan Serdar
Published: February 2024

Introduction:

Osteoid osteoma (OO) is a painful benign bone tumor. Typically, it causes pain that is most noticeable during the night, which is improved by
nonsteroidal anti-inflammatory drugs. In the treatment of symptomatic lesions, open surgery for nidus removal is the gold standard. However,
surgical technical difficulties and morbidities vary by location. Percutaneous radiofrequency ablation (RFA) therapy guided by computed
tomography (CT) is now a popular treatment option for OO. This study aims to assess our single-center experience with the technique,
complications, and procedure effectiveness.

Materials and Methods:

The study included fifteen patients who were treated between 2017 and 2021. A retrospective analysis was carried out on archive images and file
records. The lesions' location, nidus width, and affected area (cortical, medullary) were all recorded. The procedure and technical success, as well
as postoperative complications and the need for repeat ablation, were all documented.

Results:

A total of 20 patients, 18 men, and 2 women, were included in the study, and 12 of them were pediatric patients. The patients' mean age was
16.9±7.3 years old, and the mean nidus diameter was 7.1±8.7 mm. There were 13 cortical niduses, 2 intramedullary niduses, and 5
corticomedullary niduses. The lesions were in the femur (n=12), tibia (n=6), scapula (n=1), and vertebrae (n=1). Two recurrences (10%) were
observed in our patients during the follow-up. Patient with a femoral OO, the pain started again 12 weeks after the procedure and we performed
additional RFA. The patient with vertebral OO had fewer symptoms and full recovery was not achieved. Therefore, the vertebral OO was ablated
again 4 months later, and clinical success was achieved. One patient had a minor burn at the entry site that went away on its own after a short
period of time. Except for the patient who was scheduled for a repeat RFA, no recurrence has been observed so far. The primary and secondary
success rates are, respectively, 90% (18/20) and 100% (20/20).

Conclusion:

RFA has a high success rate in treating OO. The procedure failure and recurrence rates are low. There are possibilities for posttreatment pain relief,
early discharge, and a quick return to daily life. For inappropriate lesion localization, the RFA process replaces surgical treatment. The procedurerelated
complication rate is low. On the other hand, the burn during the procedure can be a serious problem.
Marine Bioprospecting
Authors: Ramesh Santhanam , Santhanam Ramasamy , Sankar Veintramuthu
Published: February 2024

 This chapter deals with the types of marine ecosystems and their
pharmaceutical biodiversity; the present status of marine bioactive compounds and
their chemical classes; therapeutic activities of marine bioactive compounds; level of
contribution of bioactive compounds by different groups of marine organisms; green
processing methods of marine drug development; and measures to tackle supply
problems of bioactive compounds.
Promising Pharmaceutical Compounds of Marine Cnidarians: Their Chemistry and Therapeutic Applications
Authors: Ramesh Santhanam , Santhanam Ramasamy , Sankar Veintramuthu
Published: February 2024

This chapter deals with the promising secondary metabolites of the different
constituents of marine cnidarians viz. hydrozoan medusae, scyphozoan medusae and
soft corals and their bioactivities. Among the chemical classes of compounds,
terpenoids ranked first and cytotoxicity of these compounds was the major activity.
Promising Pharmaceutical Compounds of Marine Bryozoans: Their Chemistry and Therapeutic Applications
Authors: Ramesh Santhanam , Santhanam Ramasamy , Sankar Veintramuthu
Published: February 2024

This chapter deals with the pharmaceutically important marine bryozoans,
their promising secondary metabolites, and bioactivities. All the bioactive compounds
of this marine invertebrate group are dealt with as per their chemical classes.
Promising Pharmaceutical Compounds of Marine Worms: Their Chemistry and Therapeutic Applications
Authors: Ramesh Santhanam , Santhanam Ramasamy , Sankar Veintramuthu
Published: February 2024

This chapter deals with the promising bioactive compounds of marine
worms such as nemertines, sipunculids, and annelids. Further, the chemical classes and
the bioactivities of these secondary metabolites are dealtwith.
The Determination of A Place of Popular Tourism on The Island of Madura Using Weighted Product (WP)
Authors: Putro Sigit Susanto , Rochman Eka Malasari , Rachmad Aery
Published: February 2024

This research explored the diverse aspects of Madura Island, including its cultural, societal, and touristic facets. The primary focus was on developing a recommendation system to identify Madura's most popular tourist destinations. Utilizing the Weighted Product (WP) method, a decision support system model, this study assessed the popularity of various tourist attractions in Madura, aiding tourists in selecting destinations through a multi-criteria weighting process. Key parameters included the number of both foreign and local visitors, proximity to the city center, and visitor ratings. The study encompassed 62 tourist sites across four districts in Madura, evaluating the most popular attractions in each. Findings revealed the top destinations in each district: Bangkalan featured Makam Syeichona Cholil (preference value: 0.113), Sampang showcased Hutan Kera Nepa (0.127), Pamekasan highlighted Batu Ampar (0.171), and Sumenep was known for Makam Asta Tinggi (0.076). This research offered valuable insights for both tourists and stakeholders in the tourism industry of Madura Island.
Visitor Decision System in Selection of Tourist Sites Based on Hybrid of Chi-Square And K-NN Methods
Authors: Anamisa Devie Rosa , Mufarroha Fifin Ayu , Jauhari Achmad
Published: February 2024

Madura Island is one of the islands with a lot of tourism spread over four districts, such as natural, religious, and cultural tourism. And every year, various visitors visit various tourist sites in Madura, so an increase in the number of visitors has been found in multiple places. This is influenced in addition to the type of tourist attraction but also changes in tourist behavior in making decisions to visit tourist objects. Most of the researchers have applied the right decision-making with intelligence-based measurement. However, the accuracy obtained has not yet reached the optimal solution. Therefore, this study uses the Chi-Square and K-Nearest Neighbors (K-NN) methods to recommend tourist attraction locations based on visitor characteristics to increase visitor attractiveness in tourist attractions scattered in Bangkalan, Madura. Chi-Square is used to select features that affect tourist attraction visitor factors by testing the relationship between the variables involved. Meanwhile, K-NN is a method of classifying potential visitor attractions based on their characteristics by using the closest membership calculation, which is the largest from the test data. The calculation is carried out by the square of the Euclidian distance from each object, then sorted from the smallest to the largest value and looking for the value of k as the result of the decision. There are ten features used in the classification, such as tourism type, management services, facilities, gender, age, occupation, education, visitor status, ticket prices, and sales trends. There are three classes classified: low, medium, and high visitor attractiveness. The contribution of this study is to analyze the effect of the characteristics of tourist attraction visitors on increasing visitor attractiveness using the chi-square and K-NN methods. Based on the results of system testing using K-Fold Cross Validation with five folds from 315 datasets, it produces the highest accuracy at k-fold = 3 worth 84.12% with eight selected features.
Ofertas tecnológicas para el manejo de la monilia y la pudrición parda en cacao (Theobroma cacao L.)
Authors: Rodríguez Polanco Eleonora , Navarro Niño Diego Alberto , Bermeo Fúquene Paula Andrea , Parra Alferes Edinson Bayardo
Published: February 2024

Colombia participa con menos del 1 % del mercado mundial de granos de cacao. El grano colombiano es referenciado internacionalmente como cacao fino y de aroma, características que solo son atribuidas al 5 % de la producción global. Existe una demanda internacional insatisfecha de cacao y sus subproductos, con grandes proyecciones de crecimiento a corto, mediano y largo plazo, por lo que es alto el potencial para incrementar la producción en el país, con miras a mejorar la tecnificación del cultivo y mantener las características de calidad que permitan abastecer nuevos mercados y mejorar las condiciones económicas de los productores. En Colombia, la producción del grano está seriamente disminuida por la moniliasis y la pudrición parda de la mazorca, enfermedades que atacan los frutos en diferentes estados de formación y comprometen directamente la producción y calidad del grano, y que llegan a causar pérdidas hasta del 80 % de la cosecha si no se controlan correctamente. Esta cartilla presenta los resultados de investigación desarrollados por AGROSAVIA a través de la generación de ofertas tecnológicas que permiten identificar estas problemáticas y realizar un manejo integrado basado en el conocimiento de la biología del agente causal y las épocas de susceptibilidad del árbol, específicamente de la fruta. Su aplicación permitirá a productores y técnicos incrementar la productividad, calidad e inocuidad del grano de cacao producido en el país.
Do Industrial Companies in Lebanon Have the Requirements to Apply Lean Accounting? An Exploratory Study of a Sample of LCPAs
Authors: El-Mousawi Hasan , Jaber Ahmad , Fakih Ibrahim
Published: February 2024

Significant changes have occurred in the industrial sector, including the adoption of Japanese management ideas such as waste reduction, quality manufacturing, employee participation, and continuous development. This change is a result of heightened competition among businesses, which makes it necessary to look for novel accounting ideas in order to adapt to changing client demands and obtain a competitive edge. The study at hand aimed to identify the availability of necessary requirements to apply lean accounting in industrial companies in Lebanon. The researchers identified two types of components, administrative and procedural. The researchers conducted a five-point Likert style questionnaire suitable to the subject and objectives of the study, and a random sample of 400 LCPA’s was selected and the questionnaires were distributed among them. The sum of 389 questionnaires were retrieved, and all were valid for testing. The descriptive analytical approach was used to describe the variables of the study and analyze them. To test the hypotheses and analyze the data, the SPSS statistical program was used. The researchers hypothesize that industrial companies in Lebanon have the administrative capabilities to implement lean accounting. The study concluded that the industrial companies in Lebanon have the administrative and procedural requirements to apply lean accounting.
Maximizing Solar Panel Performance: A Comparative Study of Aluminum and Copper Panel Integration in Off-Grid Systems
Authors: Kumar Ranjan
Published: February 2024

Abstract: This study explores the implementation of off-grid solar energy systems with strategically mounted aluminum panels behind solar panels, aiming to devise an efficient, economical, and environmentally friendly design. The research builds upon existing literature in the field, focusing on optimizing solar panel performance. Through a comprehensive analysis involving voltage, current, temperature, and solar radiation, the study achieved a notable 1-2% increase in solar panel efficiency. Notably, this enhancement is realized without the need for additional space, making the proposed design a practical and space-efficient solution. The findings underscore the potential of this approach as a permanent, cost-effective, and environmentally conscious solution for PV solar panel installations. With the escalating costs of conventional electrical energy, the study advocates for the adoption of this method, aligning with the global push towards sustainable and eco-friendly energy alternatives. The insights gleaned from this research contribute valuable knowledge to the ongoing discourse on advancing renewable energy technologies, emphasizing the significance of efficient and sustainable solutions in the transition towards a cleaner energy future.
Faktor dan Rencana Aksi Implementasi BCMS Pada Sektor Publik: Studi Kasus Pada Sekretariat Utama BPKP
Authors: Wibowo Bambang Satria A , Hermawan Ancella Anitawati
Published: February 2024

Purpose: Business Continuity Management System (BCMS) is not widely implemented in Indonesian public sector, therefore his study aims to reveal the drivers of BCMS implementation at the public sector and preparation that organization should done for BCMS implementation as required by the ISO 22301:2019 standard.  The object of the study is Chief Secretariat of Badan Pengawasan Keuangan dan Pembangunan (BPKP) which has supporting function for government’s internal audit as BPKP core-business.
Methodology/Approach: The research done with case study method with qualitative approach. The primary data in the study was collected through semi-structured interview with people from risk management unit, incidents management unit,  and IT management unit. The data analysis carried out with the benchmarking the drivers of BCMS implementation with previous study and literature and benchmarking the organizaiton existing condition with BCMS requirements.
Findings: The study found that there are urgency and need for BCMS implementation in the organization, with the main drivers are informal top-management support, uneven continuity practices, and the increase of organization’s dependency of information technology.
Practical and Theoretical Contribution/Originality: Organization need to create the BCMS policy, enhance the competency and awareness about BCMS, and update the incident response procedure as the preparations of BCMS implementation. This research contributing for future public sector implementation of BCMS.
Diferencias de género en el rendimiento lector de preescolares que asisten a escuelas vulnerables
Authors: Barriga Carmen A. , Sepúlveda Felipe
Published: February 2024

Un número importante de investigaciones han constatado la existencia de diferencias en el rendimiento lector entre niños y niñas. Sin embargo, los hallazgos no son convergentes; por otra parte, la mayoría de los estudios se han resuelto en cursos posteriores al preescolar y en sistemas ortográficos opacos. En menor medida se ha indagado el rendimiento inicial lector entre niños y niñas preescolares que asisten a escuelas vulnerables, en período de pospandemia. En este sentido, el objetivo de esta investigación fue determinar si las diferencias de género en el rendimiento lector ocurren desde edades tempranas, a pesar de que los estudiantes no hayan asistido presencialmente a las escuelas. La muestra consistió en 58 alumnos provenientes de 4 colegios públicos. A través de un ANOVA se evaluó la existencia de diferencias de género en el rendimiento lector inicial de los estudiantes. Los resultados mostraron que no existen diferencias en el rendimiento lector global entre niños y niñas, pero sí las hay entre tareas, ya que las niñas se desempeñaron mejor que los niños en tareas de conciencia de lo impreso. Por otra parte, se demostró que tanto niños como niñas obtienen mejores resultados en tareas de conciencia fonológica frente a las tareas de conciencia de lo impreso.
Aprendizajes percibidos por docentes que participan de un desarrollo profesional en línea sobre alfabetización
Authors: Balbi Alejandra , Bonilla Micaela , Techera Clara , Berrutti Sofía , Von Hagen Alexa
Published: February 2024

El desarrollo profesional docente tiene un papel fundamental en la mejora educativa, especialmente en su modalidad en línea (DPL), debido a su escalabilidad. A pesar de la creciente cantidad de DPL, pocos han sido evaluados empíricamente. Un grupo de 52 docentes de primaria participó en DPL de 152 horas y 4 meses, con un enfoque en prácticas basadas en evidencia en educación (PBEE) para la alfabetización. Se analizó cómo transitan el aprendizaje en línea y qué aprendizajes perciben y destacan a partir de su participación. El 84.6 % de los participantes no residían en la misma ciudad que la universidad responsable del programa, y el 75 % trabajaba en instituciones públicas. Se utilizó un enfoque de investigación mixta. Se recopilaron datos cuantitativos sobre la actividad en la plataforma Moodle y los resultados de las tareas. También se obtuvo información cualitativa a través de 7 entrevistas semiestructuradas y 2 grupos focales. El 98 % de los participantes completaron con éxito el DPL. Mostraron preferencia por actividades que implicaban evaluación formativa. Valoraron los aprendizajes relacionados con actividades prácticas de alfabetización y la enseñanza explícita del vocabulario. Aunque no refieren a contenidos teóricos sobre PBEE, señalaron que adquirieron respaldo en la evidencia para justificar sus prácticas. Los resultados sugieren que los DPL pueden ser efectivos si se contextualizan en la práctica docente, incorporan evidencia científica y utilizan formatos amigables, asequibles y accesibles.
Hardening and improving the corrosion resistance of carbon steel 45 with thermal chemical treatment
Authors: Timofeev M. N. , Brudnik S. V. , Pichkhidze S. Ya.
Published: February 2024

The issues of creating a hardening coating by plasma spraying of Ti powder on steel grade 45 with subsequent cementation are considered in order to improve mechanical properties and evaluate corrosion resistance. X-ray phase analysis showed the presence of basic (Fe) and strengthening phases (TiC, Fe3C) in the material under study.
Paulo Freire: múltiplos olhares
Authors: Mesquida Peri
Published: February 2024

A proposta da obra é de lançar olhares diversificados sobre o tema da Educação a partir do referencial freiriano. O leitor e a leitora encontrarão ao longo das páginas do livro, diálogos aparentemente impossíveis entre pessoas que se dedicaram à educação. Diálogos que, no livro, se tornam realidade, mostrando a complementaridade do pensamento desses teórico-práticos da educação. Afinal, Marcelino Champagnat, Vicente de Paulo, Luísa de Marillac e Paulo Freire, tinham um denominador comum: a fé católica. Poderão, ainda, tomar conhecimento da importância que Paulo Freire dava à comunicação na educação, não como expressão de comunicados, mas como diálogos em comunhão. Afinal, para Freire, o processo comunicativo é pedagógico, e a educação é comunicação. Daí nasce a educomunicação. Terão, também, um encontro com o que Paulo Freire chamava de maldade neoliberal, criticando o neoloberalismo como filosofia política, econômica e antropológica de legitimação do sistema capitalista de produção, justificando a barbárie, perpetrada contra os seres humanos e a natureza pelo capitalismo, e isso com o apoio da midia e da escola como aparelhos veiculadores do pensamento neoliberal.
The Effect of Service Quality and Price on Customer Loyalty with Customer Satisfaction as an Intervening Variable (Case Study at Hotel Dedy Jaya Brebes)
Authors: Ariyani Deva , Harini Dwi , Setiadi Roby , Syaifulloh Muhammad
Published: February 2024

The problem in this study is the decrease in demand for rooms at Hotel Dedy Jaya Brebes. The results of this study are a reference for the importance of maintaining customer loyalty, because the purpose of this study is to determine how the effect of service quality and price on customer loyalty, with customer satisfaction as an intervening variable. The research method used is a case study, which takes one particular object to be analyzed in depth by focusing on one problem. Purposive sampling technique on 86 people aged 17 years and over and have stayed or used the services of Hotel Dedy Jaya Brebes. Instrument tests are carried out with validity tests and reliability tests. This research was conducted with a Structural Equation Model (SEM) approach using Partial Least Square (PLS) software. The results showed that service quality affects customer satisfaction; price affects customer satisfaction; service quality affects customer loyalty; price affects customer loyalty; and customer satisfaction affects customer loyalty. The variable contribution of service quality and price to customer satisfaction is 75.4%, while service quality and price to customer loyalty is 82.6%. By conducting this research, it is hoped that there will be an improvement in the quality of service and prices offered by Hotel Dedy Jaya Brebes to its customers.
Dmitry Merezhkovsky Between Remy de Gourmont and Emil Ludwig
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Andrushchenko Elena A.
Published: February 2024

This article relies on statements of two Il’ins to elaborate the position of D. Merezhkovsky’s works in European literature. V. Il’in placed him among distinguished European critics by comparing him to R. de Gourmont, while I. Il’in’s parallel between him and E. Ludwig sought to undermine his contribution to the European literary biography. This is only partly justified. The article suggests that Merezhkovsky has used the same technique of mythologization in his literary criticism and biographical writings, which distinguishes his works from R. de Gourmont’s critiques and E. Ludwig’s biographies. The perception of a “hero’s” personality and works (or deeds) proceeds by reflecting the reflection, driven by a combination of three viewpoints: those of the “hero”, the author of a scientific or critical text on them and of Merezhkovsky himself. He is concerned not so much with aesthetical merits, or with reflecting the reality, as with how the personality and the works are able to express his own views. These are defined at different times by ideas that are “external” to the material being analyzed. By examining Merezhkovsky as a phenomenon between R. de Gourmont and E. Ludwig, we are able to observe evident similarities and substantial differences produced by Merezhkovsky’s particular type of bookish thinking — a phenomenon only made possible in the Russian religious and cultural renaissance.
Séraphîta by Honoré de Balzac and the Concept of the Tripartite Union of Zinaida Gippius and Dmitry Merezhkovsky: Possible Influences
Authors:   University of Strasbourg, Blinova Olga A.
Published: February 2024

The intension of this article is to reveal the influence of Honoré de Balzac’s mystical and philosophical novel Séraphîta (1835) on the life and work of Zinaida Gippius and Dmitri Merezhkovsky. Based on bibliographical data and the document of the Foreign Censorship Committee, stored in the Russian State Historical Archive (RGIA), and published for the first time, it clarifies the history of distribution and reception of the French writer’s novel in the 19th century Russia. Using textual analysis, it demonstrates the influence of Hippolyte Taine’s essay “Balzac” (1865), particularly his method and his evaluation of the novel Séraphîta on the work of Merezhkovsky in the early 1890s. The first traces of the influence of Balzac’s text discovered on the work of Gippius go back to 1895, time of the publication of her story “Miss May”. Comparison of the artistic assimilation of the image of Séraphîta-Séraphîtüs by the spouses reveals significant differences: when Merezhkovsky uses the transparency of the “corporeal envelope” of Balzac’s hero to transmit the highest spirituality of his chosen characters, Gippius, however, focuses her attention mainly on the androgyny of Séraphîta-Séraphîtüs, which becomes in her artistic universe an essential sign of “new people”. In conclusion, the discovery of the novel Séraphîta by the Merezhkovskys is included in the chronology of the genesis of their concept of tripartite union as well as in the accomplishment of the couple’s life creation (zhiznetvorchestvo).
Dmitry Merezhkovsky in Latvia: Antons Austriņš, Viktors Eglītis, Ādolfs Erss
Authors:   University of Latvia, Gordins Andrejs
Published: February 2024

The role of Dmitry Merezhkovsky and his work in Latvian culture is still understudied, while his works were demanded by a whole generation of Latvian writers and resonated in the Latvian cultural space. This article examines some intertextual connections of famous Latvian writers of the first half of the 20th century — Antons Austriņš, Viktors Eglītis and Ādolfs Erss — and Dmitry Merezhkovsky, one of the brightest representatives of Russian Symbolism and a prominent figure of the Russian Abroad. Based on references and direct quotations from Merezhkovsky, the typological affinity between representatives of the two cultures is traced in Latvian works within the processes that took place in Latvian literature, situating it within a pan-European cultural context.
Dmitry Merezhkovsky in France Under the German Occupation (Materials for the Biography of the Writer)
Authors:   New Sorbonne, Stroev Alexandre F.
Published: February 2024

The French press, archival documents, correspondence and memoirs of Russian writers who emigrated reconstruct the life of Dmitry Merezhkovsky on the Basque coast in 1940–1941. Articles, interviews and letters allow us to discover the writer’s circle of acquaintances in Biarritz, his daily life and, above all, his unknown speeches and texts. They shed light on the genesis of Merezhkovsky’s last works, The Mystery of the Russian Revolution and Europe Facing the USSR, and prove the direct link between the lectures of the summer of 1941, his article “Bolshevism and Humanity” and a possible radio speech in 1941. The writer supported the war against the Soviet Union, but did not glorify Hitler.
The Literary Criticism’s Heritage of D.S. Merezhkovsky in French During the Period of Emigration: Translations and Reviews
Authors:   Jean Moulin Lyon 3 University, Garziano Svetlana A.
Published: February 2024

The French period of D.S. Merezhkovsky needs additional coverage and more detailed research. From a literary point of view, D.S. Merezhkovsky — the author of the article “On the causes of decline and new trends in modern Russian literature”, fundamental for the literature of the late 19th century, is known in the period of post-revolutionary (lifetime) emigration by other texts. The corpus of translations of the writer’s works that are directly related to Russian literature and Russian classics includes four major books published during his lifetime: “L’âme de Dostoïevski, le prophète de la révolution russe” (1922), “Compagnons éternels” (1922), “Le mufle-roi. L’avènement du Cham” (1922) and “Gogol et le diable” (1939). In the interwar period, these texts present to the French reader Merezhkovsky’s critical heritage. An extensive number of reviews in the French press (about 30 texts) are published on them. The paper examines this little-known literary heritage in French and provides translations of some excerpts from reviews of the books cited above. Reviews in French can bring some new perspective on Merezhkovsky’s work and on the theme of the Europeanness of the writer.
Correspondence of the Merezhkovskys with N.V. Tchaikovsky
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Andrushchenko Elena A.
Published: February 2024

This publication features the correspondence of D.S. Merezhkovsky and Z.N. Gippius with N.V. Tchaikovsky of the early 1920s, when they arrived in Paris from Warsaw. In those years Tchaikovsky led the “Union of the reconstruction of Russia”, headed the undercover “Action Centre” and chaired the executive board of the Committee for Aid to Russian Writers and Scholars in France. The functioning of the Committee plays an important part in the correspondence with Tchaikovsky, yet the authors focus on the financial, not the organizational aspect. Gippius compared the activities of the Committee with the Literary Fund supervised by P.I. Weinberg. However, financial conflicts in emigration were evidently more acute and desperate, while aid was needed by the finest representatives of Russian literature and science in exile rather than by novice or poor writers. The Merezhkovskys and Tchaikovsky discussed the possibility of establishing a “Union of the Spirit”, a Russian-French publishing house, hosting meetings of the Society of Friends of Russian literature, a gathering on the occasion of Dostoevsky’s 100th anniversary, etc. The correspondence expands our understanding of the literary life of Russian émigrés in France.
Sprawozdanie z udziału w V Kongresie Stowarzyszenia Ekonomistów Rolnictwa i Agrobiznesu "Agrobiznes w krajach Europy Środkowej w aspekcie integracji z Unią Europejską"
Authors: Zawojska Aldona , Daniłowska Alina
Published: February 2024

W dniach 22-25 września 1998 r. odbył się we Wrocławiu V Kongres Stowarzyszenia Ekonomistów Rolnictwa i Agrobiznesu. Wrocław gościł ponad 200 ekonomistów z Polski, Czech, Białorusi i Rosji. Wizyta na Kongresie była dobrą okazją do wzięcia udziału w dyskusji na wiele zagadnień podzielonych na pięć szerokich tematów, a mianowicie: „Problemy ekonomiczno-organizacyjne gospodarstw rolnych”, „Problemy infrastruktury obszarów wiejskich i rolnictwa”, „Polityka rolna”, „ Przedsiębiorczość na obszarach wiejskich” oraz „Problemy doradztwa i edukacji”. Tematyka ta była poruszana podczas sesji plenarnej oraz w trakcie pięciu zaplanowanych sesji tematycznych. Autorzy niniejszego raportu wzięli udział w pierwszej i drugiej z wybranych sekcji. Raport koncentruje się na zmianach strukturalnych w gospodarstwach rolnych, na rynku ziemi rolnej (głównie ceny ziemi), regionalnym zróżnicowaniu zdolności produkcyjnych obszarów wiejskich oraz ogólnie na regionalnych różnicach w rozwoju gospodarczym Polski i innych krajów Europy Środkowo-Wschodniej. (tłumaczenie lw)
Informacja z przebiegu seminarium polskich i niemieckich doktorantów zorganizowanego 1 października 1998 roku w Szkole Głównej Gospodarstwa Wiejskiego w Warszawie
Authors: Borowska Agnieszka
Published: February 2024

W dniu 1 października 1998 r. w SGGW odbyło się Seminarium dla doktorantów polskich i niemieckich. Zorganizowano go z okazji 20. rocznicy porozumienia zawartego pomiędzy SGGW a Rheinische Friedrich-Wilhelms Universität w Bonn. Tematyka Seminarium dotyczyła problematyki badań szczegółowych prowadzonych przez doktorantów w zakresie nauk ekonomicznych, nauk weterynaryjnych, nauk rolniczych i ogrodniczych. Uczestnicy zaprezentowali wyniki swoich badań przeprowadzonych w ramach prac doktorskich. (tłumaczenie - lw)
Informacja o konferencji naukowej pt. "Efektywność działalności w agrobiznesie"
Authors: Gruziel Kinga , Wrzesińska Joanna
Published: February 2024

Dnia 22 maja 1998 r. w SGGW w Warszawie odbyła się Ogólnopolska Konferencja „Efektywność Działalności Gospodarczej w Agrobiznesie”. Jej organizatorem był Wydział Ekonomiczno-Rolniczy SGGW w Warszawie. Konferencja poświęcona była pamięci Profesora Tadeusza Rychlika – zasłużonego naukowca i nauczyciela akademickiego, byłego dyrektora Instytutu Ekonomiki Rolnictwa i Polityki Agrarnej SGGW. Dyskusje i prezentacje skupiały się na czterech ogólnych tematach: * Ramy teoretyczne agrobiznesu; * Efektywność działalności gospodarczej w polskim sektorze rolniczym; * Infrastruktura rynków rolnych; * Problemy finansowe napotykane przez działalność agrobiznesu. Podstawą debaty były artykuły opublikowane przed konferencją w Zeszytach Naukowych SGGW, Seria Ekonomika i Organizacja Agrobiznesu (nr 34 i 35). Konferencja stała się forum do zmiany poglądów i poruszyła kluczowe problemy dalszego rozwoju badań nad aspektami metodologicznymi, stosowanymi i legislacyjnymi w sektorze agrobiznesu. (tłumaczenie LW).
Compact dual-band circularly polarized antenna for wireless communications
Authors: Srivastava Karunesh , Kulshreshtha Mayuri
Published: February 2024

P-shaped dual-band circularly polarized (CP) antenna for wireless
communications with right-hand circular polarization (RHCP) and left-hand
circular polarization (LHCP) is presented in this article. Optimized
electrical volume of the proposed structure is 0.46? 0 ? 0.46? 0 ? 0.02? 0
mm3 at 4.4 GHz resonant frequency. The measured - 10 dB impedance bandwidths
are 50.7% and 5.7% for (3.37-5.60 GHz) and (10.82-11.46 GHz) resonating
bands at frequencies 4.4 GHz and 11.4 GHz respectively. The measured 3 dB
impedance axial-ratio bandwidths for (4.65-5.13 GHz) and (11.21-11.52 GHz)
bands are 9.7% and 2.7%. Agreement of simulation results with measured
results ensure the excellent circular polarization at frequencies 4.96 GHz
and 11.4 GHz.
Antiretroviral Therapy and Red Blood Cell Morphology: A Review in HIV Patients
Authors: Obeagu Emmanuel Ifeanyi
Published: February 2024

Antiretroviral therapy (ART) has transformed the management of HIV, significantly improving the prognosis and quality of life for individuals living with the virus. While the primary focus of ART has traditionally been on viral suppression and immune restoration, emerging evidence suggests a potential impact on red blood cell (RBC) morphology. This paper explores the intricate relationship between antiretroviral therapy and red blood cell morphology in HIV patients, shedding light on the multifaceted effects of these medications beyond their antiviral properties. Moving beyond laboratory findings, the review investigates the clinical implications of alterations in red blood cell morphology in individuals undergoing antiretroviral therapy. This includes discussions on potential implications for oxygen-carrying capacity, hemoglobin levels, and overall hematological health, emphasizing the need for a holistic understanding of the hematopoietic consequences of ART. In conclusion, this paper consolidates existing knowledge, identifies gaps in understanding, and provides a comprehensive resource for researchers, clinicians, and healthcare professionals involved in the care of HIV patients. It contributes to the broader conversation on the holistic effects of antiretroviral therapy, paving the way for future investigations and improved clinical management.
ANALISIS PERAN DAN PROGRAM PENDIDIKAN SEKOLAH KATOLIK DALAM PEMBENTUKAN KARAKTER SISWA DI WILAYAH KEVIKEPAN KEDU
Authors:   Universitas Sanata Dharma, Yogyakarta, Indonesia, Kevin Stefanus Kristian , Pramesti Maria Chika ,   Universitas Sanata Dharma, Yogyakarta, Indonesia, Siregar Tiur Valentina ,   Universitas Sanata Dharma, Yogyakarta, Indonesia, Gulo Mateayani Fili ,   Universitas Sanata Dharma, Yogyakarta, Indonesia
Published: February 2024

The number of cases of juvenile delinquency is a concern in Catholic education to shape and develop quality character. This study aims to analyse how the role and programmes of Catholic school education in the character building of students in the Episcopal Vicariate of Kedu. The method used in this research is a qualitative method with a phenomenological approach. The subjects in this study were 150 people involved in Catholic school education in the Episcopal Vicariate of Kedu, such as parents, school administrators, teachers, school employees and students. The subjects conducted a Focus Group Discussion (FGD) and the results of the FGD were notarised and written into a g-form as a qualitative survey. Based on the results of the study, it can be concluded that Catholic education in the Kevikepan Kedu region has a very important role and programme in character building such as faith-based education, good teacher role models, retreat and live-in activities, education in the church, modern technology, and adequate curriculum so as to form characters who are.
TEOLOGI BELASKASIH ALLAH DALAM PUISI “SEPOTONG HATI DI ANGKRINGAN” (2022) KARYA JOKO PINURBO
Authors:   Prodi Pendidikan Keagamaan Katolik, Universitas Sanata Dharma, Yogyakarta, Indonesia, Prihartanti Marcelina , Andalas Patricius Mutiara ,   Prodi Pendidikan Keagamaan Katolik, Universitas Sanata Dharma, Yogyakarta, Indonesia
Published: February 2024

Every human being longs for intimacy with God, receiving His merciful grace. Many of Joko Pinurbo's poems raise the theme of the closeness of human relations. One of Pinurbo's articulate poems voicing social compassion is entitled "A Piece of Heart in Angkringan." However, the theological reading of God's mercy in the poem "A Piece of Heart in Angkringan" has not been explored among professional Indonesian theologians. Pope Francis encouraged pastoral theologians as "influencers of the Gospel" to utilize narrative, aesthetic and digital sources to communicate the Catholic faith to the world. Theological research on this poem can contribute to deepening the theology of God's mercy amidst the challenges of globalization of indifference. Both authors are interested in exploring the theology of God's mercy in the poem "A Piece of Heart in Angkringan" by Joko Pinurbo. How does poet Joko Pinurbo describe God's mercy in the poem "A Piece of Heart in Angkringan?" The two authors want to connect the social compassion implied in the poem "A Piece of Heart in Angkringan" with the theology of God's mercy. This research applies a theological reading method to poetry. The research results show the theological content of God's mercy in the words and metaphors that poet Joko Pinurbo explores in the poem "A Piece of Heart in Angkringan." The poet Joko Pinurbo's poetic exploration aligns with Pope Francis' exploration of the theology of God's mercy: "God is present amid His people, a presence that expresses His compassion and solidarity" (Misericordiae Vultus).
A Post-Pandemic New Normal for Interest Rates in Emerging Bond Markets? Evidence from Chile
Authors:   University of San Diego, Ceballos Luis , Christensen Jens H. E. ,   Federal Reserve Bank of San Francisco, Romero Damian ,   Banco Central de Chile
Published: February 2024

Before the COVID-19 pandemic, researchers intensely debated the extent of the decline in the steady-state short-term real interest rate—the so-called equilibrium or natural rate of interest. Given the recent sharp increase in interest rates, we revisit this question in an emerging bond market context and offer a Chilean perspective using a dynamic term structure finance model estimated directly on the prices of individual Chilean inflation indexed bonds with adjustments for bond-specific liquidity risk and real term premia. We estimate that the equilibrium real rate in Chile fell about 2 and a half percentage points in the 2003-2022 period and has remained low since then.