bluuebunny/crossref_metadata_2025 huggingface dataset:
Modern Paradigm Towards Potential Target Identification for Antiviral (SARS-nCoV-2) and Anticancer Lipopeptides: A Pharmacophore-Based Approach
Authors: Yadav Manisha , Eswari J. Satya
Published: January 2022

Background: Lipopeptides are potential microbial metabolites that are abandoned with broad spectrum biopharmaceutical properties ranging from antimicrobial, antiviral and anticancer, etc. Clinical studies are not much explored beyond the experimental methods to understand drug mechanisms on target proteins at the molecular level for large molecules. Due to the less available studies on potential target proteins of lipopeptide based drugs, their potential inhibitory role for more obvious treatment on disease have not been explored in the direction of lead optimization. However, Computational approaches need to be utilized to explore drug discovery aspects on lipopeptide based drugs, which are time saving and cost-effective techniques.
Methods: Here a ligand-based drug discovery approach is coupled with reverse pharmacophore-mapping for the prediction of potential targets for antiviral (SARS-nCoV-2) and anticancer lipopeptides. Web-based servers PharmMapper and Swiss Target Prediction are used for the identification of target proteins for lipopeptides surfactin and iturin produced by Bacillus subtilis.
Results: The studies have given the insight to treat the diseases with next-generation large molecule therapeutics. Results also indicate the affinity for Angiotensin-Converting Enzymes (ACE) and proteases as the potential viral targets for these categories of peptide therapeutics. A target protein for the Human Papilloma Virus (HPV) has also been mapped.
Conclusion: The work will further help in exploring computer-aided drug designing of novel compounds with greater efficiency where the structure of the target proteins and lead compounds are known.
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Authors: . .
Published: January 2022

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Antitumor Activities of Green Tea by Up-regulation of miR-181a Expression in LNCaP Cells Using 3D Cell Culture Model
Authors: Safari Fatemeh , Rayat Azad Narjes , Alizadeh Ezdiny Ali , Pakizehkar Safoora , Khazaei Koohpar Zeinab , Ranji Najmeh
Published: January 2022

Background: Prostate Cancer (PCa) is the major reason for the high mortality rates among men worldwide. In fact, current therapeutic approaches are not successful. It appears that discovering more effective methods considering several parameters such as availability, low cost, and no toxicity to normal cells is one of the biggest challenges for interested researchers. Green tea (extracted from the plant Camellia sinensis) with high level of polyphenolic compounds and as the most globally consumed beverage has attracted considerable interest. MicroRNAs (or miRNAs) were considered as novel tools in cancer therapy which modulate various biological events in cell by regulation of gene expression. The aim of the current study was to evaluate the antitumor activity of green tea in LNCaP cells through up-regulation of miR-181a expression.
Methods: First, LNCaP cells were cultured and by using quantitative real time PCR (qRT-PCR) and western blot methods, the expression levels of Bax and BCL2 were analyzed. Next, a 3D cell culture model was applied to evaluate the expression of miRNA-181a in LNCaP cells. 
Results: It was shown that green tea induced cellular apoptosis. The high number of apoptotic nuclei was also shown by using DAPI staining. The inhibition of tumor growth was revealed by analyzing the size and number of spheroids. Also, up-regulation of miR-181a expression in LNCaP cells was revealed after treatment with green tea.
Conclusion: Our results are helpful to design antitumor regimens based on consumption of green tea through up-regulation of miRNA-181a expression and induction of apoptosis.
The second strategic plan of medical ethics: a national report
Authors: Parsapour Alireza , Shamsi Gooshki Ehsan , Malekafzali Hossein , Zahedi Farzaneh , Larijani Bagher
Published: January 2022

Medical ethics faces several challenges in different aspects of education, research, and treatment in medicine and healthcare practice. Design and implementation of a national strategic plan can pave the way for the development of a roadmap in various countries to strengthen ethics and address these challenges. 
To create a comprehensive plan compatible with the Iranian healthcare system, a multidisciplinary team of main stakeholders compiled a national strategic plan of medical ethics following several focus group discussion sessions and two workshops (2014-2017). Ultimately, the plan was confirmed by the Supreme Council for the Medical Ethics of the Ministry of Health and Medical Education.
The current paper is a national report of the process and the medical ethics strategic plan in Iran. We have also tracked signs of progress and achievements in the country.
In conclusion, this valuable effort has led to significant success in the implementation of medical ethics in clinical medicine, medical research, and education by using all the resources in our country. The participation of all the stakeholders, especially healthcare professionals in this way is required.
Telephone communication with relatives of hospitalised COVID-19 patients by a specialised family support team: lessons learned
Authors: Ayora Ara , Nogueras Carme , Jimenez-Panes Sonia , Cortinas-Rovira Sergi
Published: January 2022

During March and April 2020, the number of hospital admissions and deaths due to the first wave of COVID-19 peaked. The objective of this study was to analyse the experiences of a team of health professionals in charge of breaking bad news over the telephone to the relatives of patients admitted to the respiratory ward of a large hospital in Barcelona.
This was a qualitative research based on semi-structured individual interviews with all the members of the team and a group interview. The interviews were analysed using Condensation of Meaning techniques.
Three central themes emerged after analysing the interviews: (1) the call itself, (2) the need for good organisational support both before and during a crisis, and (3) the care that the professionals themselves need.
To set up a large-scale operation to break bad news over the phone, some organisational aspects must be considered that go beyond the call itself. All these aspects are interrelated to a large extent, and due attention should be given to proper communication and adequate care practices for both relatives and health workers.
The role of narrative medicine program in promoting professional ethics: perceptions of Iranian medical students
Authors: Daryazadeh Saeideh , Adibi Payman , Yamani Nikoo
Published: January 2022

Narrative medicine (NM) is an educational tool that can be used to promote the professional competencies of medical students. This study aimed to investigate Iranian medical students’ perceptions of the first NM program offered in 2019.
The study was conducted on 69 medical interns who participated in the weekly NM program that was part of the professional ethics course for two months. We used a questionnaire to determine medical interns' perceptions and personal attitudes toward NM. Three experts confirmed the validity of the questionnaire in Persian, and its reliability was verified by internal consistency (α = 0.879). The independent t-test was used to compare the differences in the total scores of students' perceptions. Data analysis was conducted using SPSS 23 software (P < 0.05).
The response rate to the questionnaire was 95.65%. The results showed overall students' perceptions of the program were found to be positive. Furthermore, the scores showed a significant difference in terms of gender (P = 0.014), but none in terms of marital status (P = 0.936).
According to the results, NM was effective in improving students’ reflections and their empathy with patients. Therefore, it is recommended to include NM in professional ethics education.
Initial drafting of telemedicine’s code of ethics through a stakeholders’ participatory process
Authors: Shafizadeh Hamid , Larijani Bagher , Mojtahedzadeh Rita , Shamsi Gooshki Ehsan , Nedjat Saharnaz
Published: January 2022

Telemedicine can improve access to healthcare services; however, it has raised ethical concerns demanding special considerations. This study aimed at developing the codes of ethics for telemedicine, and hence several approved national and international ethical guidelines related to telemedicine practice were reviewed, and 48 semi-structured interviews were conducted with medical ethics and medical informatics experts as well as with physicians and patients who had telemedicine experiences. Content analysis was then performed on the interviews’ transcripts and a draft on code of ethics was prepared, which was further reviewed by the experts in the focus group meetings to reach a consensus on the final document. The final document consisted of a preface, five considerations, and 25 ethical statements. Considering the growing trend of adopting telemedicine worldwide, this document provides an ethical framework for those who use telemedicine in their medical practice.
The Efficacy of an Intervention Program for Pain Intensity Reduction in Patients Undergoing Arterial Sheath Removal after Coronary Artery Angioplasty
Authors: Heidaranlu Esmail , Sedghi Goyaghaj Naser , Moradi Ali , Ebadi Abbas
Published: January 2022

Background: Pain management after sheath removal is one of the most significant points in patient care. The use of a simple, practical, and combined method in this field is essential. The purpose of this study was to evaluate the efficacy of an intervention program for pain intensity reduction in patients undergoing arterial sheath removal after coronary artery angioplasty.
Methods: This semi-experimental study was conducted in 2020 on 90 eligible patients selected via the purpose-based method and randomly assigned to experimental and control groups. The intervention program for the experimental group included training to relax the abdominal muscles, deep and slow breathing, and precise pressure on the femoral pulse. Pain intensity was measured before, during, and several times after arterial sheath removal. The independent t, Fisher exact, and χ2 tests were used to analyze the data.
Results: Women comprised 66.6% of the study participants, who had a mean age of 58.20±8.70 years. No significant differences were observed concerning pain intensity, bleeding, pseudoaneurysm formation, and hematoma between the 2 groups before the intervention (P=0.531). However, during the intervention and in the fifth and tenth minutes after the intervention, pain intensity was lower in the experimental group (P<0.050), whereas no such differences were observed regarding bleeding, pseudoaneurysm formation, and hematoma.
Conclusions: Given the effectiveness of our intervention program in ameliorating pain intensity and vasovagal response after arterial sheath removal, we suggest that this program, along with prescription drugs, be used for the management of patients’ pain.
Longitudinal Stent Deformation in Undeployed Stents: A Case Series
Authors: Singh Otaal Parminder , Bootla Dinakar
Published: January 2022

Longitudinal stent deformation (LSD) is a recently reported problem with newer generation stents. The modification of stent materials and designs to make them more deliverable and conformable, as well as a focused approach in retaining their radial strength, has compromised longitudinal strength in currently available stents. Additionally, enhanced stent radiopacity, improved fluoroscopy, and heightened awareness have led to an increased incidence rate of the potentially under-recognized problem of LSD. Although originally described in deployed stents, LSD is being recognized in undeployed stents too. With available data to suggest an increased rate of adverse cardiac events like stent thrombosis and in-stent restenosis with LSD in deployed stents, an attempt to retrieve an undeployed deformed stent appears justified. We report 3 cases of LSD in undeployed stents and discuss its recognition. We also discuss the retrieval and visual inspection of retrieved stents and the simultaneous completion of coronary interventions via a double guide technique.
Incomplete Removal and Accidental Retention of Temporary Epicardial Pacing Wires in the Chest after Heart Surgery: A Case Report
Authors: Khalili Ahmadali , Jodati Ahmadreza , Rahimi Mehran , Faravn Amir , Parizad Razieh
Published: January 2022

Temporary pacemaker wires are commonly used for the diagnosis and treatment of arrhythmias in the acute postoperative period. We herein describe a 65-year-old woman with a history of coronary artery bypass graft surgery who was referred to the hospital with a purulent discharge in the lower third of the sternal region while on antibiotics. Two years later, following treatment failure, 2 sternal wires were removed. Several years after the surgery, the patient developed a purulent discharge. On suspicion of rib osteomyelitis, the last left cartilage attached to the sternum was excised and removed together with an infectious tract.
During the operation, the right ventricle was torn, and tampons were used to control bleeding. The patient was placed under cardiopulmonary bypass via the cannulation of the left femoral artery and the right femoral vein. The sternum was opened, and the rupture site was repaired. A temporary epicardial pacing wire was found at the site of the right ventricular rupture.  Several days later, the patient was taken from the intensive care unit to the operating room due to a pulsatile hematoma in the left groin and a diagnosis of a pseudoaneurysm of the femoral artery. After a week, the purulent discharge at the lower sternum improved, and the patient was discharged. At 1 month’s post-discharge follow-up, the infection was eradicated
A Case of Isolated Bicuspid Pulmonic Valve and Pulmonary Artery Aneurysm
Authors: Sahebjam Mohammad , Toofaninejad Neda
Published: January 2022

A 33-year-old woman with a history of thyroid surgery for thyroid cancer and radioactive iodine therapy was referred for echocardiography due to dyspnea on exertion.
Transthoracic echocardiography showed normal left ventricular size and function (the ejection fraction = 55%), a prolapsing mitral valve with redundant chordae, mild mitral regurgitation, a tricuspid aortic valve, mild aortic insufficiency, and mild tricuspid regurgitation. The most remarkable echocardiographic findings were moderate right ventricular dilation with mild systolic dysfunction, moderate right atrial dilation, an aneurysmal pulmonary artery (the main pulmonary artery = 47 mm), mild pulmonary stenosis (the peak gradient = 22 mmHg), and severe pulmonary regurgitation (the vena contracta = 6–7 mm and the pressure half time = 105 ms).
Transesophageal echocardiography with the use of 3D modalities demonstrated a bicuspid pulmonic valve with doming and poor coaptation of the pulmonic valve leaflets (Figure 1). Additionally, a large patent foramen ovale was visualized in color Doppler (the flap separation = 2 mm and the tunnel length = 11 mm) with bubble passage in agitated saline injection.
Bicuspid pulmonic valves constitute a rare finding, and they are most often associated with other congenital heart diseases. Isolated bicuspid pulmonic valves are extremely rare, with an incidence rate of about 0.1% in clinical practice.1 Pulmonary artery aneurysms also comprise a rare abnormality, with an incidence rate of approximately 1 in 14 000 cases in most studies.2 The association between bicuspid pulmonic valves and pulmonary artery aneurysms has been reported, and the pathophysiologic causes of this association include hemodynamic alterations due to bicuspid pulmonic valves and most likely the abnormal migration of neural crest cells.3
 The diagnosis of a bicuspid pulmonic valve by 2D imaging is challenging and sometimes impossible. Using 3D echocardiography and reconstruction confers a better assessment of the pulmonic valve morphology and identification of bicuspid pulmonic valves.
Investigating the relationship between low back pain and quality of life in emergency medical personnel and the role of demographic variables in this regard
Authors: Khosravi Bonjar A , Ahmadi Chenari H , Bazaz Kahani H , Mohammadi M
Published: January 2022

Introduction: Back pain is one of the most important occupational problems among health care workers that have detrimental effects on their personal and professional life. Therefore, this study aimed to investigate the relationship between low back pain and quality of life in prehospital emergency staff and the role of demographic variables in this regard.
Materials and Methods: This is a descriptive correlational study. The population was a prehospital emergency staff that entered to study by using the census method at 2020. Data gathering instruments were demographic characteristics, low back pain, and quality of life questionnaires. Data were entered into SPSS 22 and were analyzed using descriptive and analytical statistics.
Results: The results showed that the related to the low back pain score of emergency medical technicians was 51.34± 4.149, which is high. In addition, the quality of life mean and standard deviation was 30.35± 4.851, which shows a low level. There is a significant relationship between back pain and quality of life (p = 0.001, R = 0.723).
Conclusion: Low back pain is so common among emergency medical personnel that the issue may affect a person's life and work and creates many problems in terms of personal, family, socially, economically, and professionally, which reduce their quality of life.
Mediating role of intrinsic work motivation in relationship between job commitment and professional ethics with firefighters' extra-role performance
Authors: Moghtaderi Isfahani A , Mehdad A
Published: January 2022

Introduction: A firefighting job is a demanding job that has a high degree of stress due to constant exposure to life-threatening conditions. Therefore, the present study investigates the mediating role of intrinsic job motivation in the relationship between job commitment and professional ethics with extra-role performance among firefighters in Isfahan.
Materials and Methods: The type of study was descriptive and correlational. The statistical population included all firefighters in Isfahan, from which 228 people were selected as a sample through random sampling. The instruments used include internal job motivation questionnaires (Gagne et al., 2015), job commitment (Blau, 2009), professional ethics (Hackerina, 2011), and extra-role performance (Lee and Allen, 2002). Data were analyzed by the Pearson correlation coefficient and structural equation modeling (SEM). SPSS23 and Smart PLS3 software were used for data analysis.
Results: The results showed that professional ethics has a direct effect on intrinsic job motivation, extra-role performance toward organization and individual; Intrinsic job motivation affects directly on the extra-role performance toward an individual; Job commitment has a direct effect on intrinsic job motivation and extra-role performance toward the organization (P <0.05). Also, the proposed model has a good fit and by examining the indirect and mediating effects through the bootstrapping method in PLS software, was shown that intrinsic job motivation mediates the effect of job commitment and professional ethics on the extra- role performance toward the individual.
Conclusion: The findings of the present study showed that professional ethics and job commitment could increase extra-role behaviors through intrinsic job motivation. Therefore, due to the role and importance of extra-role behaviors in the firefighting profession, attention to this should be considered by managers and policymakers of this organization.
Modeling NOx, CO, SO2 and PM emissions from Sabzevar cement plant using SCREEN3 software
Authors: Keykhosravi SS , Nejadkoorki F , Toosi Amin
Published: January 2022

Introduction: Nowadays, the cement industry is regarded as one of the most important air pollution industries globally. This study aimed to simulate the emission of NOx, CO, SO2, and PM pollutants caused by the Sabzevar Cement Factory chimney by SCREEN3 software. 
Materials and Methods: In this study, the SCREEN3 software was employed for the distribution of NOx, CO, SO2, and PM pollutants. The inputs of the model include the concentration and emission of pollutant gases, physical factors associated with the cement factory chimney, wind speed and direction, ambient temperature, and stability classes. 
Results: The results of this study indicated that the maximum concentrations of NOx, CO, SO2, and PM by the SCREEN3 software occurred in unstable weather conditions (B) and wind speed of 5 m.s. The highest concentrations of NOx, CO, and PM (use of gas) were at a distance of 1400 meters from the factory chimney with the rates of 0.9, 0.32, 6.2 μg.m³, respectively. Moreover, the highest concentrations of NOx, CO, SO2, and PM (using fuel oil) were predicted at a distance of 1100 m from the factory chimney with 19.5, 360, 9, and 7.9 μg.m³, respectively. A comparison of the obtained results with the standard of the Environmental Protection Agency of Iran (EPA) revealed that the concentrations of NOx, CO, SO2, and PM were not higher than the standards. 
Conclusion: The comparison of results with EPA standard and Iranian clean air standard showed that NOX, CO, SO2, and PM concentrations were not higher than standards during the sampling period.
Evaluation of total and differential white blood cell counts in workers exposed to lead
Authors: Kargar-Shouroki F , Mehri HR , Sepahi-Zoeram F
Published: January 2022

Introduction: Lead is a toxic heavy metal that has adverse health effects on blood parameters. About 80% of lead produced is used in batteries, especially vehicle batteries. Therefore, the present study aimed to assess the hematological changes, including total and differential white blood cell (WBC) counts in battery workers exposed to lead, and compare with the non-exposed group.
Materials and Methods: This cross-sectional study was carried out in a battery industry in Semnan city. The study population consisted of 78 battery workers and 78 healthy non-exposed office workers. A hematology cell counter was used to determine the total, and differential WBC counts. Blood lead level was measured in accordance with the NIOSH method 8003.
Results: Blood lead levels were about two times higher than the TLV recommended by the American Conference of Governmental Industrial Hygienists (ACGIH) for this compound (20 µg/dl). The level of WBC (8.07± 2.55 mm3 blood×103 vs. 7.27 ± 1.58 mm3 blood×103) was significantly higher, while the level of monocyte was significantly lower (6.96 ± 1.72 % vs. 7.67 ± 1.87 %) in the exposed group than in the non-exposed group. After adjustment for potential confounders such as age and work history, a significant association between exposure to lead and WBC and monocyte levels was reported.
Conclusion: The present study's findings indicated that exposure to lead was associated with total and differential white blood cells changes in the exposed group compared to the non-exposed group.
Psychological consequences of firefighters' working conditions: A Qualitative Study
Authors: Zeraat Herfeh F , Shamsi Nezhad M , Rahmati A
Published: January 2022

Introduction: A high-risk job, firefighting involves a wide range of tasks. Given the difficult nature of the job with all the responsibilities included, and in addition to the impending physical injuries, firefighters undergo several emergencies which can endanger their psychological health. Therefore, the present study was conducted to investigate the psychological consequences of firefighters' work conditions.
Materials and Methods: The research method was qualitative and phenomenological. Using the purposeful sampling method, 16 firefighters were selected from fire stations across the city of Kerman, Iran; saturation criteria were used in the selection of participants. Data were collected using semi-structured interviews and analyzed using Colaizzi’s seven-step method. In this way, first, the interviews were coded, and then based on the similarity of codes, 4 main categories were extracted. 
Results: results showed that persistent stress (caused by the sound of fire alarms and announcement of fire emergencies, trying to make it to the scene on time, worrying about not being on time, and not finding the address of the incidents, complications, and uncertainties of the incidents), sleep problems (these include sleep disturbances, insomnia, difficulty maintaining sleep, startled waking up, somniloquy), negative emotions reminiscent of painful events, and difficulty in establishing good relationships with family members, are the most important psychological consequences that firefighters faced due to their working conditions.
Conclusion: Considering the important role of firefighters in providing services in emergencies, the psychological consequences of this job are risk factors that harm the health and the performance of firefighters. Therefore, appropriate measures and planning need to be taken to manage and reduce ongoing stress and improve the quality of firefighters' sleep. To manage and reduce negative emotions and their family problems, appropriate training should be provided.
Role of an architect in projects involving EPC contracts
Authors: Dasyapu Adyathan , Nagubilli Greeshmika , Kutcharlapati Jayanth V , Guntuku Hari Prasad , Nagdeve Shruti S
Published: January 2022

Purpose: Engineering, procurement, and construction (EPC) contracts are on their way to becoming the most common type of contract used by the private sector for large-scale infrastructure projects. Every project requires a strong relationship between all of the experts participating in EPC projects and the client. This relationship must be solidly established by an architect; otherwise, the project may fail for all parties involved, including the client, contractor, lenders, government, and others. The purpose of this study is to identify if the working of the EPC contracts is favourable for the architectural profession, and to identify the way in which the working could be improved.

Methodology: A qualitative approach was applied to analyze the critical points of EPC contracts based upon reviews of related case studies from the public sector and supplementary interviews with professionals in the field.

Main Finding: The architect's role in an EPC contract is not crucial and is equal to other stakeholders involved in the project. Also, EPC contractors have the power to dictate the workflow of the project and hence, architects might have to compromise in terms of the design, compensation, etc.

Implications: It is very important for every project to have an outcome based on each stakeholders/consultants inputs specially on larger projects, this article is a step towards understanding the role of architects under an EPC contract as the future projects will come under its purview. 

Novelty: The study is done under the lens of a newly graduated architect and not as any other professional, thereby trying to develop an understanding for fresh architects.
Estrategias de lectura y rendimiento académico en la transición a la educación superior
Authors: Herrera-Nuñez Yudi , Dapelo Bianca
Published: January 2022

La transición a la universidad es un proceso de adaptación de enorme complejidad que desafía a las instituciones a generar mecanismos para promover la persistencia de los estudiantes hasta su egreso. Este estudio busca aportar a la comprensión del uso de estrategias de lectura y su relación con los logros académicos de los estudiantes durante la transición a la educación superior. La metodología es cuantitativa, con una muestra no probabilística intencionada de 145 voluntarios: estudiantes de educación media de establecimientos con alto índice de vulnerabilidad y estudiantes ingresantes de una universidad estatal de la Región de Valparaíso en Chile, mediante la aplicación de un instrumento. Entre los principales resultados, se encuentra que los grupos de estudiantes de educación secundaria y universitaria se diferencian significativamente en el tipo y en el uso de estrategias de lectura, las cuales se correlacionan directa y significativamente con el rendimiento académico y son relevantes, ya que usar diferentes estrategias incide en el nivel lector de estudiantes con bajo rendimiento académico, especialmente, en la educación media.
Proyectos musicales en secundaria: una herramienta para facilitar la socialización en adolescentes
Authors: Cremades-Andreu Roberto , García-Sanz Julio
Published: January 2022

En la sociedad actual, los jóvenes conforman su identidad influenciados por diferentes agentes que marcan su forma de actuar, su desarrollo personal y la interacción social en su grupo de pertenencia. Así, el propósito de este artículo es mostrar cómo la realización de un proyecto musical escolar, en el que los estudiantes tienen una participación activa y son los protagonistas de su propio aprendizaje, puede ser una herramienta que genere un clima de trabajo que favorezca la socialización y el respeto hacia los demás. Para ello, se entrevistaron a los participantes —16 estudiantes de 15 a 17 años, tutora y orientadores— de un proyecto musical llevado a cabo en un instituto de educación secundaria de la ciudad de Madrid, España. Los resultados muestran cómo la participación democrática en la toma de decisiones y el desarrollo del proyecto en grupo fueron factores motivacionales para los estudiantes, quienes además superaron sus conflictos y mejoraron su autoestima, que se incrementó por el valor que le dieron a la calidad de la puesta en escena el día de la presentación final.
Meta-Analysis the Root of Terrorism from the Perspektif Islamic Movement in Indonesia
Authors: Dinda Rosanti Salsa Bela  , Achmad Nurmandi  , Isnaini Muallidin  , Danang Kurniawan
Published: January 2022

This paper aims to map the root of terrorism in Indonesia from the Islamic movement perspective. The authors want to know how the root of terrorism has strengthened in Indonesia. A qualitative method approach was taken through a literature study regarding the delivery of research map information while the data was exported in the RIS Export file format. Then, the authors exported the data and processed it using VOSviewer to find out a bibliometric map of research development based on significant themes of Indonesian terrorism cases. Nvivo 12 plus provided exploration and description of terrorism in Indonesia to get an efficient explanation of the data. The findings are, the first to map the issue of terrorism in Indonesia. First, there was a correlation between terrorism, radicalism, and Islam. Different views of religious teachings eventually led to the terrorism movement. Several radical Islamic organizations in Indonesia have portrayed Islam as a terrorist religion. Second, the factors causing the strengthening of terrorism in Indonesia were due to injustice, oppression, and discrimination leading to terrorism and radicalism using the concept of jihad. This research suggests that the government can handle terrorism cases in Indonesia and neutralize ideas that are considered radical with a de-radicalization approach. (Tulisan ini bertujuan memetakan akar terorisme di Indonesia dari aspek gerakan Islam. Penulis ingin mengetahui bagaimana akar terorisme menguat di Indonesia. Pendekatan metode kualitatif ditempuh melalui studi pustaka sedangkan untuk penyampaian informasi peta penelitian, data diekspor dalam format file Ekspor RIS. Kemudian, penulis mengekspor data dalam format (RIS), mengolahnya menggunakan VOS viewer untuk mengetahui peta bibliometrik pengembangan penelitian berdasarkan tema signifikan kasus terorisme di Indonesia dan menggunakan Nvivo 12 plus untuk memberikan eksplorasi dan deskripsi terorisme di Indonesia demi mendapatkan penjelasan yang efisien dari data. Temuan penelitian ini adalah; Pertama, pada tahap pemetaan isu terorisme di Indonesia, terdapat korelasi antara terorisme, radikalisme, dan Islam. Perbedaan pandangan terhadap ajaran agama pada akhirnya memunculkan gerakan terorisme. Beberapa organisasi Islam radikal di Indonesia telah mencitrakan Islam sebagai agama teroris. Kedua, diketahui faktor penyebab menguatnya terorisme di Indonesia adalah rasa ketidakadilan, penindasan dan diskriminasi yang berujung pada gerakan terorisme dan radikalisme dengan mengusung konsep jihad. Saran dari penelitian ini adalah agar pemerintah dapat menangani kasus terorisme di Indonesia dan menetralisir ide-ide yang dianggap radikal dengan pendekatan deradikalisasi.
Islamic Philanthropy and Poverty Reduction in Indonesia: The Role of Integrated Islamic Social and Commercial Finance Institutions
Authors: Iskandar Azwar , Bayu Taufiq Possumah  , Khaerul Aqbar  , Akhmad Hanafi Dain Yunta
Published: January 2022

The recent studies about the role of Islamic philanthropy in addressing socio-economic problems have been growing and confirming its significant role in overcoming the problem. This is in line with the existence of regulations that support the effectiveness of its role in poverty reduction in Indonesia, such as Law No. 23 of 2011 on Zakat Management and Law No. 41 of 2004 on Waqf. This study has two objectives. First, to analyze the impact of Islamic philanthropy on poverty reduction as the socio-economic problems in Indonesia in the short and long run. Second, to analyze the effectiveness of integrated Islamic commercial and social-economic or finance to address the poverty compared to unintegrated one. This study used Auto-Regressive Distributed Lag (ARDL) approach to analyze annual data for the period of 2002-2019 while investigating the long and short-run relationships among variables. It found that Islamic philanthropy reduces poverty both in the short and long run, particularly in the integration of Islamic social and commercial finance in a single model. The government should therefore include Islamic philanthropy or other Islamic social finances as a fundamental strategy for building financial stability and sustainable development. (Menjamurnya studi-studi terbaru terkait peran filantropi Islam dalam mengatasi masalah sosial-ekonomi telah mengkonfirmasi peran pentingnya dalam mengatasi masalah ini.  Hal ini sejalan dengan adanya regulasi yang mendukung efektivitas perannya dalam pengentasan kemiskinan di Indonesia, seperti Undang-Undang Nomor 23 Tahun 2011 tentang Pengelolaan Zakat dan Undang-Undang Nomor 41 Tahun 2004 tentang Wakaf. Penelitian ini memiliki dua tujuan. Pertama, untuk menganalisis dampak filantropi Islam terhadap penurunan tingkat kemiskinan sebagai sebuah permasalahan sosial-ekonomi di Indonesia, baik dalam jangka pendek maupun jangka panjang. Kedua, untuk menganalisis efektifitas integrasi atau antara filantropi dan komersial dalam kerangka ekonomi Islam dalam mengatasi permasalahan kemiskinan. Penelitian ini menggunakan pendekatan Auto-Regressive Distributed Lag (ARDL) untuk menginvestigasi hubungan jangka pendek dan jangka panjang antara filantropi Islam dan tingkat kemiskinan selama periode tahun 2002-2019. Penelitian ini menemukan bahwa filantropi Islam dapat menurunkan tingkat kemiskinan baik dalam jangka pendek maupun jangka panjang. Penelitian ini juga menemukan bahwa ketika filantropi dan komersial dalam kerangka ekonomi Islam diintegrasikan, tingkat kemiskinan dapat diturunkan baik dalam jangka pendek maupun jangka panjang. Pemerintah seyogiyanya menempatkan filantropi Islam sebagai kebijakan dan strategi fundamental dalam rangka mewujudkan stabilitas keuangan dan pembangunan berkelanjutan.)
Changes in Congregational Prayer Practices During the Covid-19 Pandemic in Aceh	from Maqashid al-Sharia Perspective
Authors: Abdul Muthalib Salman , M. Jakfar Tarmizi , Maulana Muhammad , Hakim Lukman
Published: January 2022

Covid-19 has changed the habits of almost all activities of human life, including religious matters. The worship practices have also changed, such as performing prayers at home, keeping distant rows, and wearing masks. This paper is empirical legal research that seeks to examine the living law in the Aceh society with a maqashid shari’a perpective during a pandemic. The data collection techniques were interview, observation, and document study. It concludes that the government policies, including the 2020 Large-Scale Social Restrictions (PSBB), the 2021 Implementation of Community Activity Restrictions (PPKM), fatwas of Indonesian Ulema Council (MUI) and Tausiyah of Acehnese Ulema regulating and calling for restrictions on religious activities are rules with benefit values and in accordance with the principle of maqasid al-shari'a. Despite some people's rejection, the policies are, in fact, based on maqasid al-shari'a, namely protecting the life (hifz al-nafs) so that people will not get infected by the virus. Moreover, public safety is the highest law purpose to maintain. The policies also prove the state's role through the rule when conditions endanger the community in addition to avoiding harms as a part of Islamic law orders. (Covid-19 telah mengubah kebiasaan hampir seluruh aktivitas kehidupan manusia, mulai dari ekonomi, sosial, budaya, pendidikan bahkan agama. Pada aspek agama aktivitas ibadah juga mengalami perubahan misalnya himbauan shalat di rumah, menjaga jarak saf dan memakai masker. Tulisan ini merupakan penelitian hukum empiris yang berupaya menelaah hukum sebagaimana yang terjadi dalam realitas masyarakat dengan pendekatan hukum Islam saat pandemi. Sedangkan teknik pengumpulan data yang dipakai adalah wawancara, observasi dan studi dokumen. Kajian ini menyimpulkan bahwa pada awalnya himbauan sebagai pemerintah tidak secara menyeluruh diikuti oleh masyarakat karena setiap daerah berbeda tingkat penularan dan kondisi covid terjadi. Setelah aturan PPKM 2021 diterapkan hal ini relatif teratur termasuk di Aceh karena dibedakan empat level dan berdasarkan tingkat penularan dan korban yaitu, merah, orange, kuning dan hijau. Kebijakan pemerintah agar tidak salat jamaah di masjid pada saat kondisi penularannya tinggi sebenarnya mengacu pada konsep maqashid syari’ah yaitu menjaga jiwa (hifz al-nafs) agar masyarakat tidak tertular virus. Meskipun sebagian masyarakat khusus daerah atau kabupaten yang tingkat penularannya rendah menganggap bahwa shalat berjamaah di masjid tetap harus dilakukan dengan pertimbangan menjaga agama (hifz al-din) sesuai protokol kesehatan. Namun patut dicatat kebijakan pemerintah tersebut mengandung kemaslahatan yang bertujuan untuk menghindari kemudharatan dan menolak bahaya sebagaimana disebutkan dalam kaidah fikih. Sehingga menghindarkan diri dari kemudharatan dan taat kepada pemerintah juga merupakan perintah syariat Islam.)
Forensic Examinations of Cybercrime
Authors: SARAWAGI Ketan , GAUTAM Ila
Published: January 2022

The growth of the internet has also resulted in the creation and growth of cybercrime due to ease of availability and connections through world web. Cybercrime is a major issue facing society today, requiring law makers and law enforcement agencies to take action. This issue can have a major impact on governments, businesses, and individuals and thus deserves the attention of researchers.
Phishing: A Present Threat
Authors: PREDU Adrian
Published: January 2022

Phishing can be seen as a threat that keeps growing day by day, which has as a primary objective the obtaining of money from different kind of customers, through fraud. In less than two decades, this illegal practice managed to become an industry with an annual worldwide financial impact of billions of dollars. This paper tries to explain what phishing means and how it evolved into a global threat, presents the main types of phishing techniques that are currently used, as well as solutions against them.
A Survey of Privacy and Security Issues in Social Networks
Authors: SPÂNU Constantin
Published: January 2022

Social networking sites such as Facebook and Twitter have gained more popularity in recent years. Because of its large user base, and large amount of information, they become a potential channel for attackers to exploit. Many social networking sites try to prevent those exploitations, but many attackers are still able to overcome those security countermeasures by using different techniques. Social network users may not be aware of such threats. Therefore, this paper will present a survey on different privacy and security issues in online social networks. The issues include privacy issues, identity theft, social networks spam, social networks malware, and physical threats. Social network privacy issues, social network security issues, social network threats, identity Theft, social network spam, social network malware, Facebook worms, Twitter Worms.
Interações sociais mediadas por WhatsApp:
Authors: Martins Sidney Pires , Dos Santos Mateus José
Published: January 2022

O presente trabalho disserta sobre as interações sociais mediadas por WhatsApp durante o desenvolvimento da disciplina Jogos de Negócios ofertada para o curso Lato Sensu em Gestão Financeira de uma instituição privada situada na cidade de Viçosa-MG. As interações realizadas nesta plataforma enriqueceram as atividades implementadas no âmbito da disciplina suscitando discussões efetivas sobre os conteúdos abordados e explorando atitudes e valores dos sujeitos imersos nos grupos. Todas as interações foram supervisionadas pelo professor regente da disciplina e as manifestações dos estudantes constituíram o corpus a ser analisado neste trabalho com o intuito de discutir a importância do WhatsApp como ferramenta didática com potencial de propiciar a aprendizagem. O corpus delimitado foi submetido a uma análise qualitativa descritiva que busca evidenciar as contribuições dos estudantes dentro da plataforma supracitada e avaliar seus desdobramentos na construção do conhecimento. Com base nos dados, o WhatsApp se mostrou como um importante recurso pedagógico que pode ser utilizado recorrentemente para auxiliar os docentes em busca de aulas ainda mais colaborativas e interativas.
territorialidade do empreendedorismo cultural
Authors: Neri dos Reis Neves Joyce , Davel Eduardo
Published: January 2022

Estudos sobre empreendedorismo têm se conectado cada vez mais com territórios como bairros, cidades e países. Entretanto, as discussões sobre as relações entre empreendedorismo e territorialidade se apresentam de forma escassa. Quando tratamos de empreendedorismo cultural e territorialidade, as pesquisas praticamente inexistem. É preciso discutir tais relações, pois o empreendedorismo cultural requer a interação entre experiências vividas e crenças pessoais com uma localidade. Diante disso, se faz necessário a adoção de uma perspectiva capaz de compreender as particularidades da relação entre empreendedorismo e territorialidade. O objetivo desta pesquisa é identificar, descrever, categorizar e discutir a influência da identidade territorial na dinâmica do empreendedorismo cultural. A pesquisa é teórico-empírica, baseada em uma etnografia audiovisual. Os resultados da pesquisa fornecem uma perspectiva teórica para repensar o empreendedorismo cultural a partir da relevância da territorialidade, destacando suas dimensões identitárias e experienciais.
A Primeira Década de Metas Anuais do Judiciário:
Authors: Oliveira Leonel Gois Lima
Published: January 2022

O objetivo deste estudo consiste em analisar a adoção de Metas Anuais no segmento da justiça estadual, no período de 2004 a 2013, pela ótica dos ex-conselheiros. Os principais questionamentos a serem respondidos foram: Quais os procedimentos gerados com a adoção de Metas anuais para o Judiciário por parte do CNJ? Qual perspectiva positiva ou negativa a tentativa de unificar contextos tão distintos que eram vivenciados em cada um dos Tribunais estaduais? Foram entrevistados 20 ex-conselheiros, adotando-se a análise temática. As categorias estabelecidas para análises foram relacionadas às metas (organização interna; controle; prazos) ou a centralização (padronização dos procedimentos, contexto local) dos tribunais estaduais. Percebe-se uma conscientização maior da importância da utilização de ferramentas de gestão para a obtenção de resultados mais satisfatórios por parte dos tribunais. Entre as ferramentas de gestão mais citadas estão as que envolvem a categoria de centralização (planejamento estratégico, metas e levantamento de dados). Obteve-se, também, um olhar gerencial ao reforçar os esforços de promoção da eficiência com a diminuição dos desvios e o monitoramento dos dados. Destaca-se as três categorias identificadas com as entrevistas, a saber: i) a divulgação tardia em relação à definição do orçamento; ii) a ausência de comprometimento; iii) a necessidade da figura do Administrador Judicial.
Análise das práticas de logística reversa (LR) na região Sul Fluminense, após a implementação da Política Nacional de Resíduos Sólidos (PNRS).
Authors: Da Silva Bitencourt Janinne , Toledo Hernández Cecilia
Published: January 2022

A Política Nacional de Resíduos Sólidos (PNRS) é um marco brasileiro em relação a gestão dos resíduos sólidos. Neste contexto, a legislação, não somente a brasileira, se torna cada vez mais rigorosa em relação ao descarte de produtos no final de seus ciclos de vida. Entretanto, paira a dúvida se realmente o programa legal está sendo considerado importante nas empresas. Com base neste contexto, o objetivo da pesquisa é avaliar a importância de motivadores da logística reversa (LR) em empresas da Região Sul Fluminense, no setor automobilístico, após a implementação da PNRS. O estudo tem caráter aplicado e exploratório e a coleta de dados foi feita por meio de questionários. A fim de analisar as informações obtidas, utilizou-se o método Analytic Hierarchy Process (AHP). Nesta pesquisa, o programa econômico foi considerado o mais importante seguido do programa legal. Outro estudo feito na Região Sul Fluminense por Hernández et al. (2010), também teve como destaque o programa econômico. Entretanto, em grau de priorização, o programa legal não foi considerado um motivador de LR, sendo que no atual estudo este se encontra em segundo lugar em termos de importância. Como recomendação de pesquisa futura, a análise pode ser feita em outras regiões e setores.
Regulamentação Profissional:
Authors: Seixas Rosa Rodrigo , De Souza Yuri , Teodoro Pítias , Vasconcellos da Silva Yuri
Published: January 2022

O objetivo desta pesquisa foi ‘Relacionar a formação e prerrogativas de atuação profissional do Administrador com a atividade de avaliação prevista na NBR 14.653-4 – Avaliação de empreendimentos’. A pesquisa possui abordagens qualitativa e quantitativa, cuja coleta de dados foi realizada por meio de entrevistas pessoais junto a especialistas e pesquisa documental, tendo os projetos pedagógicos de 59 cursos de Administração e Engenharia (Civil e Produção) como objeto de pesquisa. Os resultados mais relevantes indicam que há convergência quanto a opinião dos especialistas ao reconhecer que o Administrador está apto a realizar a avaliação de empreendimentos e que sua formação acadêmica, em media possui maior aderência aos requisitos da norma NBR 14.653-4, que de Engenheiros (Civil e de Produção).  Entretanto, normas infraconstitucionais de regulamentação profissional definem o grupo de profissionais registrados no CREA (engenheiros, agrônomos, geólogos, geógrafos e dos meteorologistas) como aquele apto a realizar a atividade de avaliação de empreendimentos com base na NBR 14.653-4. Os resultados devem ser tratados como um indicativo sobre a regulação profissional relacionada à avaliação de empreendimentos no Brasil pois, em função das características da pesquisa não podem ser generalizados.