bluuebunny/crossref_metadata_2025 huggingface dataset:
Ethics and legal aspects of the right to die with dignity
Authors: Mirevska Ivana
Published: December 2021

Euthanasia is in liaison with ethics and law. This paper, which aims to contribute to the expert public debate on the introduction of euthanasia into Serbian legislation, the term terminology - euthanasia (as the Right to Die with Dignity) is the first to have been terminologically clarified. Furthermore, the text considers the obligations of other persons, arising out of this right and under what conditions the obligations of other persons arising from the said right constitute a restriction of their personality rights. By citing examples in the field of ethics and law, the text notes that the distinction between active and passive euthanasia is in fact a product of inadequate thinking in the implementation of this distinction. Based on the ethical argumentation of the double effect, also the text points to the inadequacy of the ethical approach in the function of legal regulation of the problem of euthanasia. Using abundant literature, which, from the legal and ethical point of view, problematizes euthanasia, the author has come to conclusion that the right to dignity is a social value that needs to be lawfully formulated, so that possible abuses can be prevented - and at the same time avoiding burdening the burden of responsibility to other persons (whether or not these are subjects of the judiciary or medicine), who should implement the patient's desire to die with dignity. Also, the author sought to base this article on the belief that Serbian legislation should legally shape the conditions for active direct euthanasia.
Influence of activities and characteristics of managers on the efficiency of strategic activities of companies in Serbia
Authors: Cvjetković Milovan
Published: December 2021

The presented research in this paper is to determine the impact of activities and characteristics of managers on the efficiency of strategic action of the company. The research included 327 managers from companies in Serbia. Correlation analysis determined the existence of statistically significant relationships between activity variables and characteristics of managers and strategic action variables. The variable communication with the variables improvement of quality and competitiveness of business, and the variable innovation and flexibility with the variables quality of vision and mission and strategic planning and decision-making showed an important connection. The regression method determined that the characteristic variables, which showed the greatest influence on the strategic operation of the company, communication, innovation and flexibility and improvement of knowledge. Factor analysis yielded a two-component solution, where the first factor brought together the variables of activity and characteristics of the manager, and the second factor the variable strategic action, and a high correlation was established between these two factors. These results indicate that the improvement of activities and characteristics of managers ensures the efficiency of strategic activities of the company. The aim of this paper is to point out the characteristic activities of management that have a great contribution to improving the efficiency of business and strategic operations of the company. Managers of domestic companies should base the improvement of business and competitiveness on the improvement of activities and characteristics of managers that have been singled out in this research.
Social inclusion policies and programs in the field of housing in the Republic of Serbia
Authors: Mihajlović-Babić Suzana
Published: December 2021

Homelessness and inadequate housing were out of public policies focus in Europe for a long time. Different theoretical approaches in defining both of these terms, as well as their different manifestations, have resulted in limited activity of the European Union and European countries in formulating housing support policies and programs for vulnerable populations. The subject of this paper are housing support programs in the Republic of Serbia, with the aim of social inclusion of poor population. The objectives of the paper are to describe, analyze and compare available housing support programs in Europe and Serbia, while the method of research is content analysis of relevant political, strategic and legal documents in this field. Based on the analysis, it is concluded that there is a narrow understanding of the concept of homelessness and housing deprivation in public policies in our country, that no specific national strategy is represented and that the programs are dominantly focused on emergency and temporary accommodation services.
Sustainable marketing in the function of sustainable urban mobility
Authors: Vujović Sonja , Vujović Tanja
Published: December 2021

As the survival and destiny of mankind are originally and inextricably conditioned by the state of the natural environment, it has become clear over time that man's relationship to the environment and economic growth and development at all costs were no longer possible or acceptable, and that man is, in fact, part of the ecosystem beyond whose legality will not be able to go unpunished. Faced with problems that, as a by-product of modernization, have for decades devastated and violated the quality of life in urban environments, the environmentally conscious global community has been pushing for the creation of sustainable cities and greener urban mobility. Hence the author's intention to emphasize the importance of accepting the concept of sustainable marketing in order to, by raising the collective awareness of the importance of transition to a low-emission society, encourage the substitution of urban mobility habits and behaviour that are in contrast the idea of sustainable urban form and the vision of a green city. The research is based on the use of secondary data, analysis of the content of available professional literature and relevant reports of the United Nations and national institutions, as well as on the application of descriptive methods and methods of analysis and synthesis. The article concludes by offering a framework for the implementation of sustainable marketing and measures that can be taken in the field of creating sustainable urban mobility.
Political power of a candidate for the president of the Government of Republic of Srpska: Testing concepts of R. Dahl and J. K. Galbraith on example of program and composition proposal introduction
Authors: Grebenar Bojan
Published: December 2021

Within this work, we tested possibility of practical application of concepts of political power defined in Robert Dahl's and John Kenneth Galbraith's work. These concepts were tested on the practical case of election of the head of government in the Republic of Srpska. More precisely, introduction of the program and cabinet proposal in the National Assembly of Republic of Srpska by Milorad Dodik, candidate for the president of the Government of Republic of Srpska in November 2006. This was done first through the short introduction and analysis of four aspects of political power - base, means, scope and amount of power, and Galbraith's three types of political power: condign, compensatory, and conditioned power. Based on identified elements and types of power, we defined the crucial questions to be considered in the analysis of individual cases from the political practice. After that, we applied these questions and concepts on concrete case of Milorad Dodik's address to the National Assembly with proposition of his government program and composition. Results of this work show that Dahl's and Galbraith's concepts of political power have explanatory use in the analysis of political practice and processes. However, based on conducted analysis it can be noticed that they are limited because they do not include all elements that can affect political power. It can be concluded that comprehensive analysis of political power is made more difficult by nature of political processes and by their parts that stay secret and beyond reach of research and general public.
Crop-machinery management system for field operations and adopted planning techniques for plantation sugar cane production
Authors: Folami Adisa , Obioha Eberendu
Published: December 2021

Major objectives of farm mechanization are to maximize production at minimum risks and optimum cost of equipment usage by good management planning and operation of machines to carry out sequence crop production operations for the whole farming system. Hence this study was needed at Sunti Golden Sugar Company, Nigeria to determine cost of equipment use and select appropriate tractor power and machinery for the crop cultivation, crop establishment, weed control, cane harvesting and transporting to the store for post-harvest processing for future target of 4,770 ha of sugar cane farm. Based on agricultural farm size, field operational planning factors like soil, weather/environmental conditions, each implement matched with appropriate tractor size was calculated. Costs of equipment use, ownership and operational costs for implements and tractors were also calculated. A well-drawn cropping field operations calendar was very important for crop and operational sequencing was recommended and was put in-place since the operations overlaps with multi-periods. As part of the recommendation, during the planned equipment downtime, major repairs and maintenance were to be carried out before critical field operation's period to improve pre-field and in-field efficiency for effective equipment and field operational planning and management. Determined are the values of each implement field capacity within allotted time available, actual number of implement/tractor power required, fuel and oil consumption per unit time for the sugar cane cultivation, harvesting and transporting operations at the sugar cane farm. Also appropriate earth-moving and earthwork equipment for road, irrigation and drainage structural works were also selected.
The impact of investments in permanent assets on the increase in the number of employees and their salaries by entrepreneurial sectors
Authors: Beke-Trivunac Jozefina , Peković Drinka
Published: December 2021

This work aimed to identify the impact of investments in permanent assets on the number of employees by sector and its impact on employee salaries. We draw the data from the Financial Statements Annual Bulletin published by the Serbian Business Registers Agency, representing aggregated data of all enterprises in Serbia and their analysis by sectors. The data set spans the period from 2013 to 2020. The results show a high positive correlation between investment in permanent assets and the number of employees in the manufacturing sector and information and communication sector, and a negative one in the agricultural industry. We did not find a significant correlation between investments in permanent assets and the number of employees with their salaries.
Training technology management and financial consequences of sports injuries summary
Authors: Hassan Alhddad
Published: December 2021

Sports injuries are an integral part of engaging in sports activities and occur both during training and in competition. Therefore, they can significantly afect the training process, which is why it is necessary to rationally approach the evaluation and treatment of the resulting injury, as well as the subsequent functional rehabilitation of athletes, in order to minimize the negative injury efects. The economic aspects and the significance of ankle injury have been examined in a sample of the highest paid soccer players in the world. The results indicated a functionally independent relationship between the frequency and intensity of injury, on the one hand, and chronological age, the value of transfers, and athletic performance efficacy on the other. In order to properly manage the training process in an incident situation, it is necessary to rationally approach the evaluation and treatment of injuries, as well as subsequent functional rehabilitation of athletes, in order to minimize the negative efects of injuries. question. Namely, in the most popular sports, top athletes earn astronomical earnings by engaging in sports activities. Therefore, their absence from training and competition has significant financial consequences. Management of the training process today requires significant involvement of management functions due to the need to articulate numerous factors influencing the training process and its final efects in an appropriate manner and to optimize the allocation of available resources to achieve planned goals. This demand is more and more present due to the fact that today, in top competitive sports, large financial resources are being used as a consequence of the increasingly valuable sports product that athletes, sports experts and sports organizations create.
Agility of internal audit
Authors: Jeremić Nebojša , Jeremić Miloš , Jakovljević Nemanja
Published: December 2021

The dynamic changes in the market conditions are increasingly moving away from the reactive audit planning. The increasingly prevalent approach implies agility, i.e. faster adjustment to the external and internal environment, whose result includes the improved operational performance, quality and satisfaction of audit clients. One way to introduce agility in internal audit is to adopt the methodology Scrum, a management approach applied in several project organizations in various industries. By implementing the best experiences of Scrum, a better overview, thinking, learning and adjustment would be achieved. The principles of having to check and adjust, which are inherent in Scrum, enable the teams to work efficiently in the ever-changing conditions, resulting in a high level of sustainable productivity. The paper provides an overview of the agile organizations, specific planning, Scrum principles and concepts for application in audit teams.
Modelling and evaluation of the effects of high back pressure (HBP) on refinery Flare System network
Authors: Sukairaji Aminu , Zaria Usman , Mohammed-Dabo Ibrahim
Published: December 2021

Safety and reliability of the flare system are often affected by High Back-Pressure (HBP). The primary aim of this study is to simulate a steady-state model of flare system using Aspen Flare System Analyzer and with the aid of real plant data generated from Kaduna Refining and Petrochemical Company (KRPC) Ltd, Nigeria. Three credible scenarios (normal operation/surplus fuel, cooling water failure and power failure) were considered. The results showed that the steady-state model of flare system for normal operation (Surplus Fuel), cooling failure and power failure scenario and the flare system meet performance requirements at a system back pressure of 1.01325 bar, except for cooling water failure scenario which showed the occurrence of high fluid velocity and momentum (rhoV 2). Also, flare operation at normal back pressure, for all three scenarios does not exceed design and operational limits. The work recommends that KRPC managers should review options for reducing HBP particularly for cooling failure and power failure scenarios such that the back pressure would not exceed 10% of set pressure for the conventional valves.
The influence of ground wires on the resistance and reactance of high voltage overhead power lines
Authors: Krstić Nikola , Tasić Dragan , Klimenta Dardan
Published: December 2021

In this paper, the influence of ground wires on the resistance and reactance (longitudinal impedance) of high voltage overhead power lines (OPLs) is considered and the method for its calculation is described in detail. This is important considering the power flow calculation and the design of the protection system of OPLs, especially those which use distance relays. In addition to symmetric, asymmetric operating conditions of OPLs are also studied, for the analysis of which symmetric components are used. Specifically, this meant the calculation of longitudinal impedances of OPL for positive, negative and zero sequences in each considered case. Special attention is paid to the symmetric system with zero sequences, because the influence of ground wires on the change of longitudinal impedance of OPLs is the greatest in that case. The cases of OPLs with one (110 kV OPL) and two (400 kV OPL) ground wires are considered, using the values o f their parameters that can be found in real systems. Values of longitudinal impedances, obtained with and without ground wires influence or the influence of some of their parameters, are compared, based on which appropriate conclusion is made.
Agon and the need for physical motion: Exercise in personalities who marked the 19th and 20th century
Authors: Pavlović Petar , Živanović Nenad , Milošević Zoran , Pantelić-Babić Kristina , Pavlović Danilo
Published: December 2021

Physical movement - an exercise, which springs from our being and returns to it as a gracious food, with its agon, that desire to compete with others but also with itself, helps a human being to become and remain a personality. This statement is confirmed by people who marked the 19th and 20th century. By their example and work, they not only testified the benefits of physical exercise, but also encouraged the formation of theoanthropocentrism, one of the theories of physical culture, at the end of the 20th century. Metropolitan Hadzi Sava Kosanovic, Bishop Rade, Bishop Nikolaj of Zica, Vasa Pelagic, Cedomir Milic, are just some of those who testified and encouraged others by their example not to forget about physical exercise and their body. Because in the union of body and soul sanctified by the Holy Spirit, that trinity survives only if all and each of them is taken care of, in specific. With examples of their attitude towards physical exercise and competition, which they only pointed out or others wrote about, we will lighten up a significant part of the history of physical culture.
Beginnings and development of rugby in Spain
Authors: Castellar Carlos , Pradas Francisco
Published: December 2021

The annals of rugby in Spain dates from the early years of the 20th century. In its early stages, the influence of countries such as England (due to its industries and commerce) or France (due to its geographical proximity) was very significant. The period of dictatorship (1940-1975) did not aid in developing this sport in Spain, though. Since democracy, rugby has consolidated its progression both in the masculine category and mainly in the feminine. The Spanish female rugby team is recognized as one of the best international teams. In this sense, the number of federative licenses has doubled in the last 20 years, going from 14,000 to more than 33,000 in 2018. In addition, adapted rugby has joined in this trend with the creation of a national wheelchair rugby team and federated competitions.
Psycho-administrative determinants for choice of physical education among senior secondary school students at external examination bodies
Authors: Samson Olusola
Published: December 2021

Empirical observations reveal low enrolment of senior secondary school students for physical education at external examination bodies. The poor rate of students' choice of the subject at this level is a matter of concern to professionals, given the fact of monumental benefits of physical education as a science subject to humanity. The study was conducted to examine how psycho-administrative factors influence the choice of physical education by senior secondary school students at external examination bodies (in Nigeria) to come up with modalities to increase enrolment of the subject at external examination bodies. Descriptive method was applied for the study due to large respondents involved. Self-developed validated questionnaire tagged psycho-administrative determinants for choice of physical education among senior secondary school students at external examination bodies (PADGPEAS) was applied for the research. Out of three thousand and twenty-four (3024) questionnaire forms administered, only two thousand and fifty (2950) copies completed and returned were coded for analysis, with the use of descriptive statistics of percentages and nonparametric statistics of Chi-square (x 2) at 0.05 level of significant. Results unraveled a remarkable influence of psycho-administrative variables on the choice at physical education among senior secondary school students at external examination bodies. Based on this outcome, it is suggested that utilization of variety of methods by physical education teachers will go a long way to kindle the interest of the students for the subject. Enlightenment of students and parents on the values of physical education will facilitate remarkable positive attitude of both parts that relocate their position in favor of the subject.
Analysis of the immune response in padel
Authors: Pía Cádiz , Otín Carlos , Páez Luis , de la
Published: December 2021

High intensity exercise and sports activities are closely related to a general state of inflammation that can lead to immunosuppression. This physiological response could decrease sports performance and even compromise the athlete's health. The objective of this study was to investigate the acute inflammatory response of a padel match. 15 elite players (28.2±7.9 years) participated voluntarily in the study. Different pro-inflammatory (IL-1ß, IL-2, IL-6, IL-7, IL-8, IL-12 and TNFa) and anti-inflammatory cytokines (IL-5, IL-10 and IL-13) were analyzed before and after a match. The results showed a decrease in IL-7 (p=0.007) and IL-8 (p<0.03) and increases in IL-10 (p<0.04). The results obtained suggest that the practice of high-level padel induces an anti-inflammatory response.
Influence of stand and terrain characteristics on the productivity of the Timberjack 240b tractor in pure beech stands
Authors: Miletić Boban , Danilović Milorad , Đorem Todor , Filipić Branislav , Gutalj Marko
Published: December 2021

This paper presents the results of research of the Timberjack 240b tractor equipped with a double-drum winch (work form 1 Tractor driver + 0 Assistant) in beech stand at an average elevation of 983.73 m. The research was conducted using the time and work study method, with the help of GIS technology in certain segments of research. The achieved working hours consist of 75.44% effective time and 24.56% delay time. The delay time coefficient is 1.33. In total, 47 transport cycles were realized, with 66 stopping points, an average of 1.41 per transport cycle. The average skidding distance was 221.19 m. In total, 363 logs (204.04 m3) were collected by 79 winches. The average load volume was 4.34 m3 and consisted of 5.43 pieces. Loaded tractor skidding time is strongly influenced by skidding distance and load volume in interaction with the longitudinal slope of skidding trails. To increase tractor productivity, it was concluded that the skidding roads should be built with the smallest longitudinal slope possible. Preferably, logs should be skidded downhill.
Third generation biofuels: Cultivation methods and technologies for processing of microalgal biofuels
Authors: Preradović Milica , Papuga Saša
Published: December 2021

Energy production from biomass is gaining a lot of attention. Algal oil (microand macroalgae) can be used for biofuel production. Biofuels from this type of feedstock are called third generation biofuels or advanced biofuels. Focus of this paper is on the microalgal biofuels and on the available process technologies. Very important advantage of microalgal biofuels is that microalgae can be cultivated on any type of land, with the possibility of using wastewater streams. Microalgae can be cultivated in open systems, so called "raceway ponds" or in closed systems - photobioreactors: flat panel photobioreactors, horizontal tubular, vertical tubular photobioreactors with or without airlift. Also, basic information on cultivation conditions (photoautotrophic, heterotrophic, mixotrophic and photoheterotrophic) are presented. Available technologies for microalgal biofuels production are: transesterification, fermentation, pyrolysis, hydrothermal liquefaction, anaerobic digestion and biomass to liquids (BtL). Additionally, basic information on life cycle assessment of microalgae cultivation and CO2 sequestration potential is given in the final chapter of this work.
Sleep quality and life satisfaction of railway employees
Authors: Milenović Miodrag , Milićević Nebojša , Dimitrijević Mina
Published: December 2021

The aim of the study was to examine the relationship between sleep quality and life satisfaction. The basic hypothesis was that the dimensions of quality and quantity of sleep will be statistically significant predictors of life satisfaction among employees of the Serbian Railways. A total of 126 workers working in different jobs were surveyed: dispatcher, information worker, cashier, train driver, and conductor. Respondents differed according to gender, age, and years of service. The main research variables were operationalized by The Pittsburgh Sleep Quality Index (PSQI; Buysse et al., 1989) and the Satisfaction Life Scale (SWLS; Diener et al.,1985). The results showed that based on the regression model consisting of sleep quality modalities, the criterion variable - life satisfaction (R2 = .40, p <0.01) can be statistically significantly explained. The largest individual contribution to the prediction of the criterion variable has the predictor of dysfunction during the day (b = -. 42, p <0.01), followed by sleep disorders (b = -. 22, p <0.05) and sleep duration (b = -. 22, p < 0.01). Examination of differences with respect to some sociodemographic variables showed that women show poorer quality of sleep, and that the quality of sleep decreases with age, that more sleep disorders occur, which causes dysfunctions during the day and more frequent use of medications.
Normality and normalcy: A case of -ity/-cy doublets in the BNC
Authors: Jevrić Tamara
Published: December 2021

Corpus-based research into derivational morphology can explain how affixes function, answer questions about their productivity and its relation to their synonymy, and clarify the rivalry between certain affixes and their semantic distinction. The aim of this research is to establish the similarities and differences between the nouns normality and normalcy by contrasting the suffixes -ity and -cy they contain in the British National Corpus (BNC). The focus is on the collocates which precede the nouns and the sources in which they appear. The attempt is also to understand what characterises the suffixes and their distribution. By focusing on normality and normalcy, we examine how lexical items behave in an electronically-stored corpus and whether a strong connection between meaning and form manifests itself in different word patterns highlighting different aspects of meaning.
The rise of feminism in the works by Henry James: Some narratological insights
Authors: Boyarkina Iren
Published: December 2021

James' fiction crosses many of the artificially imposed borders and often deals explicitly with social changes and their consequences, for example, the emerging role and power of women in society. James was among the first American writers to introduce feministic issues into his works. This paper explores the theme of feminism in "The Turn of the Screw", "The Jolly Corner" and The Bostonians emphasizing that in the latter James raises the problem of possibility for women of their simultaneous self-realization in family, at work, and in social life. This is still one of the most burning issues in feministic writing thus making James relevant in the 21st century. Analysing The Bostianians and shorter works by Henry James, the paper demonstrates that the writer pays a lot of attention to the issues of female personal freedom and self-realization determined by the loyalty to the institution of marriage. James depicts the growing tendency of alienation and misunderstanding between men and women, underlined in his short works and The Bostonians.
Forest pedagogy in a primary education and its perception by the pedagogues
Authors: Kollárová Dana
Published: December 2021

Currently, elementary education teachers and tutors in Slovakia express massive interest in collaboration with forest pedagogues. This collaboration focuses on fulfilling educational standards and meeting educational objectives tight to the topics of the forest environment. These are mainly the topics from the subjects of Human and nature, Human and society, Human and the world of labour. The object of the research was teachers' opinions on collaboration with forest pedagogues and the impact of forest pedagogy on the educational process.
Supportive education for children with alcohol-dependent parents
Authors: Juhásová Andrea , Balážiová Petra
Published: December 2021

This contribution deals with the influence of addiction in parents on social aspects of their children's lives. Children having a parent with an addiction are at risk of experiencing direct effects, such as parental abuse or neglect, or indirect effects, such as fewer household resources. Previous research indicates that the negative effects of addicted parents may differ depending on the type of addiction the parent has (i.e., alcohol or illicit drug). Alcoholism has many victims but perhaps the most defenseless of them are the children of alcoholics. Instead of their parents being sources of wisdom and nurturing, such children have to survive with adults who are violent, unpredictable, and given to their own impulses and desires. Children of alcoholics face risks of mental health trauma and substance abuse in their own adult years, but whether they make the choices of their parents is a complex issue. Our paper describes the scenario of addiction in the family, its impact on the family and codependence syndrome. The author's priority was to identify the consequences of parent's alcoholism on children's socialization and to describe the influence of alcohol dependence on the children's adult lives. In the conclusion of this article the author offers options of solving this issue caused by codependence.
How do the social changes influence the English language grammar?
Authors: Ljubičić Gordana
Published: December 2021

The paper deals with recent changes occurring in the English language due to the changes in the society itself. Every language is influenced by the changes happening in every aspect of human life, namely, in politics, economics, culture or human relations. The topic of the paper is how the changes in gender relations influence the English grammar, that is, the part of the grammar dealing with English pronouns. Nowadays, many people, transgender or others, refuse to be denoted by singular pronouns "he" or "she" - and choose the singular "they" instead. Although this use of "they" is not such a new thing, because the nonbinary pronoun "they" was voted the Word of the Year 2015 by American Dialect Society and again in 2019 as the Word of the Decade by the same institution, people are still sceptic about its grammatical correctness. But, this use of the pronoun is gaining in popularity, and very soon, the English language might accept these changes.
Territorio, topografía y arquitectura de poder durante la Antigüedad Tardía, MYTRA 1. Sánchez Ramos, I. y Mateos Cruz, P. (Eds.), 2018, 328 pp. ISBN: 978-84-09-015894
Authors: Serrano López Víctor José
Published: December 2021

Short review of the first volume of MYTRA series, dedicated to the evolution of the power architecture and its influence on topography and territory during the Late Antiquity.

Breve recensión sobre el primer volumen de la serie MYTRA, dedicado a la evolución de la arquitectura de poder y su influencia en la topografía y el territorio durante la Antigüedad Tardía.
Algunas imágenes del ejército romano en el siglo III (235-284)
Authors: Sancho Gómez Miguel Pablo
Published: December 2021

In this work we intend to offer a clear and concise view of some of the fundamental aspects of the Roman army that emerged from the “Crisis of the Third Century”, a traumatic period full of transformations that altered the structures of the Roman State forever. We will try to show that some of the most important changes of those key moments were linked to the army, from which the basis of well-known Later Roman Empire would emerge, ultimately represented by the reforms of Diocletian and Constantine.

En este trabajo pretendemos ofrecer una visión clara y concisa de algunos de los aspectos fundamentales del ejército romano surgido a partir de la “Crisis del siglo III”, un periodo traumático y lleno de transformaciones que alteraron las estructuras del estado romano para siempre. Intentaremos mostrar que algunos de los cambios más importantes de esos cruciales momentos estuvieron vinculados al ejército, del que surgiría la base para la aparición del consabido Imperio Tardío, representado en última instancia por las reformas de Diocleciano y Constantino.
El rescriptum del emperador Majencio sobre Lucilla de Cartago en vísperas del cisma donatista
Authors: Serra Diego , Cecini Marco , Serra Fabio Manuel , Podda Alessandro
Published: December 2021

The study of some unpublished documents coming from several European and international libraries, after the publication of Anejos VIII, and the reconsideration of other primary sources that have already been studied, would seem to confirm most hypotheses raised in the book with a good margin of probability. The comparative analysis of these documents will allow us, as follows: a) to describe the historical background of the two letters, especially with regard to the rescriptum; b) to suggest a more precise dating of this rescriptum; and c) to outline the manuscript tradition of the two letters that, starting from the legal text in Koine Greek, are transformed into an apologetic literary text by means of interpolations that mostly affected the edict of tolerance. The preliminary study of some legal papyri, in comparison with the different versions of Ep. I, allowed us to propose a critical reconstruction of the text that has undergone numerous interpolations over the centuries. The first letter perfectly matches with both the structure and the legal terminology of the Hellenistic-Roman laws, in so fully mirroring the words used by Eusebius and Optatus to describe Maxentius' edict of tolerance.

El estudio de algunos documentos inéditos procedentes de varias bibliotecas europeas e internacionales, tras la publicación de Anejos VIII, y la reconsideración de otras fuentes primarias ya estudiadas, parece confirmar la mayoría de las hipótesis planteadas en el libro con un buen margen de probabilidad. El análisis comparativo de estos documentos nos permitirá, de la siguiente manera: a) describir los antecedentes históricos de las dos epístolas, especialmente con referencia al rescriptum; b) hipotetizar una fecha más precisa de este rescriptum; y c) describir la tradición manuscrita de las dos epístolas que, a partir del texto legal en griego koiné, se transforman en un texto literario apologético mediante interpolaciones que afectan mayoritariamente el edicto de tolerancia. Además, el estudio preliminar de algunos papiros legales, en comparación con las diferentes versiones de Ep. 1, nos permitió proponer una reconstrucción crítica del texto que ha sufrido numerosas interpolaciones a lo largo de los siglos. La primera letra encaja perfectamente tanto con la estructura como con la terminología legal de las leyes helenístico-romanas, reflejando tan plenamente las palabras utilizadas por Eusebio y Optato para describir el edicto de tolerancia de Majencio.
Changes in the labour market during the COVID-19 pandemic and their spatial interactions – evidence from monthly data for Polish LAU
Authors: Ciołek Dorota
Published: December 2021

In addition to direct negative effects in terms of morbidity and mortality, the pandemic caused by SARS-CoV-2 also has indirect negative effects that concerned, among others, the labour market. This study analysed changes in the unemployment rate that were observed at the level of Polish Local Administrative Units (LAU) during the ten months of the pandemic. Both annual and monthly data were applied. Using cross-sectional and panel econometric modelling with spatial interactions it was shown that the observed increase in unemployment was strongly influenced by the share of employment in services, especially in less knowledge-intensive services such as: trade, accommodation and gastronomy. Moreover, it turns out that a higher share of women working in services was associated with a higher increase in unemployment than in the case of men working in services. Significant positive spatial relationships between local labour markets in LAUs were also identified. It was also shown that both the timing and severity of containment measures were significant. The strongest effect of the lockdown was observed three months after its introduction, while after six months the effect was significantly smaller. The study's findings may be important for post-pandemic recovery plans.
Numerical Analysis of A Nonlinear Elastic Composite Leaf Spring
Authors: ÖREN Osman , EKİCİ İrem Beyza
Published: December 2021

In this study, numerical analysis of a composite spring with a nonlinear elastic force-displacement relationship was performed. Due to the lightness and durability of composite materials, their use in the automotive industry is increasing and production methods allow for a high performance spring design. The behavior of a pair of composite leaf springs working in tandem with the cross-section profiles of the leaf springs to be obtained by using the involute curve of the spur gear pairs under load was examined in detail by numerical method, and the desired behavior was obtained. In the analyzes performed using Ls-Dyna software, samples were produced and many mechanical tests were performed for the determination of material parameters. The results obtained from these tests were used as the required material parameters in numerical analysis. The leaf spring thickness that will give the desired non-linear elastic behavior under 400 N load used in numerical analysis has been determined and successfully targeted force-elongation behavior has been created.
Ambalaj Atığı Toplama Sistemlerinin Karşılaştırmalı Sürdürülebilirlik Analizi
Authors: YILDIZ GEYHAN Eren , YILAN Gülşah , ALTUN-ÇİFTÇİOĞLU Gökçen , KADIRGAN M. A. Neşet
Published: December 2021

Maltepe Belediyesi ile ortaklaşa yürütülen bu çalışma; çevresel, sosyal ve ekonomik açıdan en uygun olan ambalaj atığı toplama sisteminin geliştirilmesini amaçlamaktadır. Bu kapsamda; mevcut ambalaj atığı toplama sistemi ve bu sisteme alternatif olarak geliştirilen 6 farklı toplama sistemi incelenmiştir. Toplama sistemlerinin sürdürülebilirlik analizinde yaşam döngü değerlendirmesi metodu kullanılmıştır. Yaşam döngü değerlendirmesinde kullanılacak olan envanter verileri; mevcut sistem analizi, saha gözlemi, anketler ve alternatif sistem hesaplamaları sonucunda elde edilmiştir. Alternatif senaryoların çevresel ve ekonomik analizi mevcut sistem verileri dikkate alınarak hesaplanırken; sosyal analiz, saha gözlemleri ve anketlere dayandırılarak yapılmıştır. Bu çalışmanın sonunda, çevresel ve ekonomik açıdan değerlendirme yapıldığında resmi toplama sistemine kıyasla, kayıt dışı toplama sisteminin daha avantajlı olduğu görülmüştür. Ancak sosyal analiz sonuçları irdelendiğinde kontrolsüz toplama sistemlerinin ciddi bir dezavantaja sahip olduğu görülmüştür. Bütüncül bir perspektifle yürütülen çevresel, sosyal ve ekonomik analiz neticesinde ortaya çıkarılan zayıflıkların, resmi ve kayıt dışı sistem entegrasyonunun önerildiği alternatif toplama sistemiyle minimize edilebileceği görülmüştür.
Electrical, Thermal, and Mechanical Properties of Mg-TiB2 Nanocomposites Produced by Spark Plasma Sintering
Authors: DİLER Ege Anıl
Published: December 2021

Monolithic magnesium was reinforced with nano-TiB2 particles to produce Mg-TiB2 nanocomposites, and the effects of nano-TiB2 particles on the electrical, thermal, and mechanical properties of Mg matrix nanocomposites were studied. Monolithic Mg and Mg-TiB2 nanocomposites were manufactured using spark plasma sintering process. Both analytical and experimental findings revealed that the electrical and thermal conductivities of Mg-TiB2 nanocomposites were lower than those of monolithic Mg and decreased as the amount of nano-TiB2 particles increased. The electrical and thermal conductivities of Mg-TiB2 nanocomposites decreased at a higher rate for a higher weight fraction of nano-TiB2 particles. The experimental electrical and thermal conductivities of Mg-TiB2 nanocomposites at a certain amount of nano-TiB2 particles was measured at lower values than those obtained by analytical calculations. The compressive strength of Mg-TiB2 nanocomposites was higher than that of monolithic Mg and improved as the weight fraction of nano-TiB2 particles increased; however, a high amount of nano-TiB2 particles resulted in a decrease in compressive strength. The compressive strength of Mg-TiB2 nanocomposite with 1.5wt.% nano-TiB2 particles improved by 34%; on the other hand, its failure strain decreased by 12% compared to monolithic Mg.
Rahim Ağzı Kanser Alt-Tiplerine Özgü Moleküler Hedef, Biyoişaretçi Adaylar ve Yeniden Konumlandırılan İlaçların Belirlenmesi
Authors: TURANLI Beste
Published: December 2021

Hassas tıp uygulamaları, geleneksel tedaviden farklı olarak kanser hastaları arasındaki bireysel farklılıkları dikkate alarak hastaları sınıflandırır. Yapılan alt tipleme ile kanser teşhisi ve tedavi yanıtının tahmini için yeni biyobelirteçlerin belirlenmesi gerekmektedir. Bu çalışmada, sistem biyolojisi yaklaşımları kullanılarak, rahim ağzı kanserinin en yaygın onkojenik iki türü olan HPV-16 enfekte ve HPV-18 enfekte grupları ayrı ayrı incelenmiştir. Her iki alt-tip için kanserin gelişimi ile ilgili ayırıcı biyobelirteçler sunularak, hassas tıp uygulaması olabilecek alt-tip spesifik teşhis ve tedavi yöntemleri sunma konusunda moleküler hedefler sunulması amaçlanmıştır. Literatürde var olan çalışmalar, hastalık heterojenliği ve alt-tip bilgilerinden bağımsız olarak doğrudan rahim ağzı kanserine odaklanmıştır. İlk defa bu çalışmada HPV-16 ve HPV-18 enfekte hasta grupları ile ilgili transkriptomik veri ayrı ayrı çalışılmıştır. Rahim ağzı kanserinde alt-tip spesifik diyagnostik, prognostik ve ilaç hedefi olabilecek biyobelirteçlerini belirlemek için mikrodizi meta-analizi yapılmıştır. İlk olarak incelenen protein-protein etkileşimlerindeki hub proteinlerde iki alt-tipte de ortak olan 8 protein (AR, AURKA, BRCA1, CDKN2A, EZH2, MYC, PCNA, STAT) dışında, 17’şer protein alt-tiplere spesifik hub proteinler olarak bulunmuştur. Transkripsiyonel düzenlemede önem arz eden TF ve miRNA’lar arasında işaretçi molekül algoritması ile ön plana çıkanlar bulunmuştur. TF’lerde alt-tipleri ayırt edebilecek belirgin farklılık gözlenmemekle birlikte, sadece HIF1α HPV-18 enfekte grubunda işaretçi TF bulunmuştur. HPV-16 spesifik sadece hsa-miR-101-3p ve hsa-let-7d-5p bulunmuştur. HPV-18 enfekte gruba spesifik ise 81 miRNA vardır. Çalışmanın en sonunda ise hub proteinlerin bazılarını hedef alan ilaçlar üzerinden ilaç yeniden konumlandırma yapılmıştır. HPV-16 enfekte kanser tedavisi için ibuprofen ve procainamide ilaçları; HPV-18 enfekte kanserler için ise hydralazine ve memantin önerilen ilaçlardandır.
Structural Modification of Ibuprofen as new NSAIDs via DFT, Molecular Docking and Pharmacokinetics Studies
Authors: OYENEYİN Oluwatoba , IPİNLOJU Nureni , OJO Nathanael , AKERELE Daniel
Published: December 2021

Inflammations generate uneasiness. This study adopts quantum mechanical and molecular docking approach to model and explore twenty derivatives of ibuprofen as potential non-steroidal anti-inflammatory drug candidates taking ibuprofen as the standard. Optimization and calculation of the drug-like quantum chemical parameters of the compounds were conducted at DFT/B3LYP/6-31G* level of theory. Binding affinity, interaction and inhibition of the potential drug-candidates with human COX-2 receptor were investigated using molecular docking studies. Pharmacokinetic properties were studied. The drug candidates interact effectively and spontaneously with the COX-2 receptor via hydrogen bonding and π-π stacking with great binding affinity. The energy gap, global hardness and softness, and chemical potential of the derivatives suggest that they are kinetically unstable, more chemically reactive than the parent drug and are effective electron donors. From the pharmacokinetic studies, all the derivatives are not substrates to permeability glycoprotein (suggesting reduced therapeutic failure), not efficiently permeable to skin, can be absorbed by human intestine and can cross the blood brain barrier. Some derivatives are potential CYP1A2, CYP2D6 and CYP3A4 inhibitors. All the ibuprofen derivatives exhibit comparable drug-likeness with standard
PEDAGOGICAL PRINCIPLES OF EFFECTIVE FORMATION OF PROJECT THINKING IN FUTURE BACHELORS
Authors:   Chechen State University, Osmaeva E.I. , Yarychev N.U.
Published: December 2021

According to the content of the provisions of the Federal State Educational Standard of Higher Education (3 ++), a future Bachelor must possess many types of universal competencies. At the same time, the readiness for project activities stands out quite strongly among others in the scale of the necessary abilities. Since the project is inherently a holistic and complete product, it is assumed that all other types of competencies should be thoroughly developed. In this light, works devoted to the development of fundamental rules for the formation of project thinking become relevant. At the same time, it turns out that such a development of the principles of the formation of the desired skill, which would take into account the strengths of the Russian conjuncture of thinking, is in demand. The authors seek to emphasize the connection between the principles of design thinking with such an organic pedagogical condition as collective activity. Since we are talking about the category of higher education, it is quite appropriate to add that it is precisely collective research activity that is meant. In this light, the purpose of the study is to develop pedagogical principles for the eff ective formation of project thinking in future bachelors. The research methodology is determined by the works of Yu. S. Manuilov. In particular, we are talking about the environmental approach, in which the social environment should play an active role, with which the future bachelor should enter into active creative relations with a research bias. The leading research method is the questioning of students. The tool for the formation of the studied quality will be a complex of active teaching methods, among which it is proposed to take into account the game methods of teaching adults (business games). The authors also believe that an underestimated method in the higher education environment is the game of chess, which was also included in the toolkit for the formation of project thinking. The following pedagogical principles were developed: 1) synergy - the unity of personal and collective creative activity, 2) conformity to nature - the organic nature of the forming conditions, 3) economy - the desire of the system for the formation of project thinking to save didactic and methodological resources, 4) fascination ‒ the orientation of the active forms used learning to remove psychological barriers to mastering theory, often presented in overly cloying academic language.