bluuebunny/crossref_metadata_2025 huggingface dataset:
PRODUÇÃO DE HIDROCARVÕES DE Eucalyptus grandis PARA BIOSSORÇÃO DE AZUL DE METILENO
Authors: Andrade João Gabriel da Silva , Porto Carlos Eduardo , Moreira Wardleison Martins , Batistela Vagner Roberto , Scaliante Mara Heloísa Neves Olsen
Published: February 2022

Embora o Brasil se destaque na produção de eucalipto (Eucalyptus grandis) ainda não há uma destinação totalmente sustentável para resíduos, ocorrendo geração de milhões de toneladas de resíduos advindos do setor madeireiro. Dessa forma, este trabalho objetiva produzir hidrocarvões por carbonização hidrotérmica de biomassa de eucalipto para aplicações como biossorventes. O preparo dos hidrocarvões foi realizado em meio ácido (EUC-A) e básico (EUC-B) a 200 ou 240 °C, por 12 ou 24 h. Neste estudo, os hidrocarvões apresentaram rendimento variável, sendo a melhor condição a de 200 °C e 24 h. Verificou-se a presença de grupos funcionais correspondentes à celulose, hemicelulose e lignina nas bandas dos espectros de ATR-FTIR. O pH 11,0 apresentou as maiores porcentagens de adsorção, sendo 95% para os hidrocarvões EUC-A e 97% para o hidrocarvões EUC-B. Dessa forma, a hidrocarbonização dos resíduos de eucalipto apresenta grande potencial de destinação como biossorventes, promovendo assim maior sustentabilidade neste setor.
THE PREPAREDNESS OF PRE-SERVICE TEACHERS ON THE REQUIRED PROGRAMS TO MEET STANDARDS
Authors:   Senior Education Program Specialist, Teacher Education Council Secretariat, Department of Education, Pasig City, Philippines PhD Student, Emilio Aguinaldo College, Paco, Manila, Philippines, B. Bihasa Donnabel
Published: February 2022

“A quality education begins with the best teachers”, Pyne, 2014. Capacitating the teaching force helps in the improvement of learners’ performance. Attracting the best educators in the profession, where respect, nobility, and prestige were sustained by exhibiting quality teaching to produce the best output or performance and an untiring motivation for student's learning will have a positive impact. As an educator let us live by this famous quote, “Teaching is the noblest profession” and uphold its meaning by being a model to our learners. This qualitative study which involved three participants tried to scrutinize the preparedness of the PSTs on the required teacher preparation programs to meet standards offered by the Department and use descriptive narrative to treat the gathered data. It also explored the practices of the TEIs in preparation for the challenges of the pre-service teachers when they are already in the school. The results of this study stated that there is already familiarity among the pre-service teachers on the existing programs offered by the department for the professional learning and development of in-service teachers. And the pre-service teachers planned to engage and participate in continuing education, school learning action cells, in-service training, seminars, and workshops for upskilling and reskilling and for professional development
PENGEMBANGAN PRODUK READY TO USE THERAPEUTIC FOOD (RUTF) BERBENTUK BAR BERBAHAN KACANG HIJAU, SEREALIA, DAN MINYAK NABATI
 Development of Ready to Use Therapeutic Food (RUTF) Bar Product Made from Mungbean, Cereal, and Vegetable oils

Authors: Novia Reni , Setiawan Budi , Marliyati Sri Anna
Published: February 2022

Pemberian produk RUTF (Ready to Use Therapeutic Food) merupakan salah satu solusi untuk mengatasi malnutrisi akut berat pada balita. Penelitian ini bertujuan untuk mengembangkan dan menganalisis produk RUTF berbentuk bar dari kacang hijau, serealia, dan minyak nabati untuk balita malnutrisi akut berat. Penelitian ini menggunakan Rancangan Acak Lengkap Faktorial dengan dua faktor dan dua ulangan. Faktor tersebut terdiri dari faktor A (kombinasi penggunaan tepung kacang hijau dengan jenis serealia yaitu tepung beras atau tepung jagung), dan faktor B (minyak nabati yaitu minyak kelapa atau minyak kelapa sawit). Penentuan formula terpilih didasarkan pada uji organoleptik (uji hedonik) dan kandungan gizi produk (energi dan protein). Hasil analisis uji hedonik menunjukkan bahwa atribut warna, aroma, rasa tekstur dan keseluruhan produk tidak berbeda nyata antar formula dan semua formula cenderung disukai panelis. Perlakuan kombinasi penggunaan tepung kacang hijau dengan serealia berpengaruh secara signifikan terhadap kandungan protein sedangkan perlakuan penggunaan minyak nabati berpengaruh secara signifikan terhadap kandungan energi produk. Hasil penelitian menunjukkan bahwa formula yang dipilih adalah formula A1B1 (kombinasi penggunaan tepung kacang hijau dengan tepung beras dan minyak kelapa) yang mengandung energi 522 kkal, 3.42% kadar air, 2.32% kadar abu, 13.57% protein, 28,89% lemak, 51,81% karbohidrat, serat pangan 4.66%, zat besi 13.82 mg /100g, kalsium 348.24 mg/100g, daya cerna protein 94.93%, dan aktivitas air 0.21. Formula A1B1 memenuhi persyaratan standar produk RUTF untuk semua kandungan gizi dan aktivitas air kecuali kandungan air berdasarkan WHO (2007).
Application of Diabetes Self-Management Education and Support in Outpatients with Type II DM
Authors: Ratnasari Indah , Ngadiarti Iskari , Ahmad Lilik Fauziyah
Published: February 2022

Education through self-management and support plays an important role in providing knowledge and instilling an awareness of the importance of healthy living. The purpose of this study was to determine the effect of Diabetes Self-Management Education and Support on eating habits, body weight, nutritional status, and glycemic control. The design of this study was quasi-experimental with the experimental design of the Pre Test Post Test without a control group. The number of samples was 60 patients who were taken by purposive sampling with predefined inclusion and exclusion criteria. Interventions were conducted 2 times a month for 6 months. From this study, it is known that for 6 months there was an increase in the consumption of vegetables, fruit, and milk (p<0,05), a significant decrease in the consumption of tubers and starches (p <0.05), while the consumption of rice and side dishes did not experience a significant change (p> 0, 05). Besides, there was a significant decrease in glycemic control (p <0.05) but there was no significant reduction in body weight and nutritional status (p> 0.05). The application of Diabetes Self-Management Education and Support for 6 months can influence glycemic control and change eating habits.
CLINICAL MANIFESTATION OF BMI, TLC, ALBUMIN AND CD4 AFTER PROVISION OF SNAKEHEAD NUGGET AND COLORED FRUIT JUICE TO PEOPLE WITH HIV
Authors: Ria Ngena , Siahaan Ginta , Nasution Zuraidah , Saragih Hanna Sriyanti
Published: February 2022

Snakehead fish has high content of zinc and albumin, it can be given to people with immune disorder. Snakehead fish can be made into various kind of food product that are high in nutrients, have aestetic value, and taste like nugget. The effectiveness of zinc and albumin function can work optimally when the consumption is combined with food ingredient that are high in bioactive substances such as lycopene, anthocyanin, flavonoid, karetonoid, bromelain, papain and quercetin. The purpose of this study was to analyze the effectof snakehead nugget administration and colored fruit juices simultaneously on clinical manifestation, BMI, TLC, albumin and CD4 value in PLHIV at HIV/AIDS Rehabilitation Center in Medan.  The design of research was quasy experimental with pre and post test design. The subjects was 40 people who lived at HIV/AIDS Rehabilitation Center in Medan and given snackhead fish nugget and colored fruit juice for 24 days. The data analysis used dependent T-test, after data normality test had previously been carried out. There was effect before and after administration of snakehead fish nuggets and colored fruit juice on clinical manifestation, BMI, TLC and CD4 levels with p value <0.05. It is necessary to provide treatment in  longer term as preventive measure for the emergence of various clinical manifestations as well as to increase BMI, TLC, albumin and CD4 in PLHIV at HIV/AIDS Rehabilitation Center in Medan.
Tumor-derived exosomes: immune properties and clinical application in lung cancer
Authors: Wu Jing , Li Suyao , Zhang Pengfei
Published: February 2022

Lung cancer is the leading cause of cancer-related death worldwide. Despite advances in diagnosis and treatment of lung cancer, the overall survival remains poor. Evidence indicates that lung cancer development is a complex and dynamic process that involves interactions between tumor cells and their microenvironments, including immune cells. Exosomes are small extracellular vesicles secreted by most cell types; they contain functional molecules that allow intercellular communication. Tumor-derived exosomes (TEXs) carry both immunosuppressive and immunostimulatory mediators and may be involved in various immunomodulatory effects. TEXs, which partially mimic profiles of the parent cells, are a potential source of cancer biomarkers for prognosis, diagnosis, and prediction of response to therapy. In addition, TEXs may interfere with immunotherapies, but they also could be used as adjuvants and antigenic components in vaccines against lung cancer. In the context of lung cancer, identifying TEXs and understanding their contribution to tumorigenesis and the response to immunotherapies represents a challenging research area.
Contôle douanes - DGDDI - aspects contractuels
Authors: Désilets Michel
Published: February 2022

La procédure de contrôle principalement inquisitoriale présente la particularité de recourir au droit des contrats sur deux aspects particuliers.
 L’estimation de la valeur des marchandises dites fraudées d’une part, et le recours dans certains cas à la transaction d’autre part.
Les développements qui suivent se proposent d’examiner juridiquement les rouages de ces singularismes.
INTERPRETAÇÕES PÓS-FUNCIONALISTAS DO ESPAÇO NA PÓS-GRADUAÇÃO EM GEOGRAFIA
Authors: Rodrigues Julian Islan Martins
Published: February 2022

O presente trabalho busca repensar as bases epistêmicas da geografia humana como produção de sentido/saber docente, a partir da experiência de formação continuada, apresentando como possibilidade uma geografia humana integrada, construída numa visão conjunta material-fenomênica de seu objeto de análise, o espaço. Fundamentamos nossa discussão, além de revisão bibliográfica, nos relatos das contribuições de professores do Programa de Pós-graduação em Geografia da Universidade Federal do Amazonas (UFAM), contribuições postas em duas respectivas aulas, no âmbito da disciplina “epistemologia da geografia” do curso de mestrado, no ano de 2018, caracterizando esta pesquisa como bibliográfica e narrativa/qualitativa ao apresentar histórias de vida. Os referidos professores são a Dra. Amélia Nogueira, que contribuiu com uma aula expositiva sobre fenomenologia na geografia e o Dr. José Aldemir [in memorian], que expos a teoria tríádica do espaço de Henri Lefebvre. Nos possibilitando interpretar uma geografia humana integrada como saber docente, em detrimento da tradicional cisão da geografia, tão comum nos programas de pós-graduação a nível de mestrado e doutorado. A divisão clássica entre geografia física e humana, também está em processo na própria geografia humana, com o florescer da geografia humanística e/ou cultural. Buscamos, para tanto, a partir dos relatos de experiências/saberes, buscar superar esse vício em fragmentar a geografia, destacando a importância da compreensão do espaço em totalidade, um todo complexo, colaborando para uma formação de professores-pesquisadores de geografia em totalidade, vide que o conhecimento geográfico deve ser construído sob o princípio da complexidade.
RESERVAS EXTRATIVISTAS DO MÉDIO PURUS E ITUXI E AS FRONTEIRAS DE DESENVOLVIMENTO PARA O SUL DO ESTADO DO AMAZONAS
Authors: Franco Marcelo Horta Messias , Oliveira Marcelo Leles Romarco de
Published: February 2022

No presente trabalho, o debate sobre a criação das Reservas Extrativistas do Médio Purus e Ituxi é realizado sob o prisma da Ecologia Política e no contexto dos modelos de desenvolvimento com influência na região sul do estado do Amazonas. Uma análise aproximada do posicionamento dos atores sociais envolvidos no processo de reconhecimento dessas duas unidades de conservação de uso sustentável na Amazônia pelo Estado revela a tensão existente quando opostas fronteiras se entrecruzam no mesmo território. Como recursos metodológicos, privilegiou-se a análise documental e a análise bibliográfica, além da obtenção de dados primários em campo. Concluiu-se que a emergência de projetos de grande vulto econômico, incidindo na região sul do Amazonas, vem contribuindo com o quadro de tensão social existente, acirrando os conflitos socioambientais.
Public Health Policy Pillars for the Sustainable Elimination of Zoonotic Schistosomiasis
Authors: Janoušková Eva , Clark Jessica , Kajero Olumayowa , Alonso Sergi , Lamberton Poppy H. L. , Betson Martha , Prada Joaquín M.
Published: February 2022

Schistosomiasis is a parasitic disease acquired through contact with contaminated freshwater. The definitive hosts are terrestrial mammals, including humans, with some Schistosoma species crossing the animal-human boundary through zoonotic transmission. An estimated 12 million people live at risk of zoonotic schistosomiasis caused by Schistosoma japonicum and Schistosoma mekongi, largely in the World Health Organization’s Western Pacific Region and in Indonesia. Mathematical models have played a vital role in our understanding of the biology, transmission, and impact of intervention strategies, however, these have mostly focused on non-zoonotic Schistosoma species. Whilst these non-zoonotic-based models capture some aspects of zoonotic schistosomiasis transmission dynamics, the commonly-used frameworks are yet to adequately capture the complex epi-ecology of multi-host zoonotic transmission. However, overcoming these knowledge gaps goes beyond transmission dynamics modelling. To improve model utility and enhance zoonotic schistosomiasis control programmes, we highlight three pillars that we believe are vital to sustainable interventions at the implementation (community) and policy-level, and discuss the pillars in the context of a One-Health approach, recognising the interconnection between humans, animals and their shared environment. These pillars are: (1) human and animal epi-ecological understanding; (2) economic considerations (such as treatment costs and animal losses); and (3) sociological understanding, including inter- and intra-human and animal interactions. These pillars must be built on a strong foundation of trust, support and commitment of stakeholders and involved institutions.
New Method to Estimation Electrical Stresses on 300kV OHTL/Cable Joints Due to Switching Operation Using ANN to Determine the Insulation Lifetime
Authors: M.A.S. Mahmoud Muhammad
Published: February 2022

This article discuss the estimation of electrical stresses input that is required to determine lifetime degradation of the HV cables installed within overhead transmission lines (OHTL’s). Abort from lightning effects, these electrical stresses are mainly generated due to repetitive switching operation of the transmission line that produces transient overvoltage (TOV) stress and high frequency stress. The transient overvoltage (TOV) due to switching-off the transmission line at the interface points between the cable and OHTL is estimated using artificial neural network (ANN). PSCAD software is used to build the transmission line model for 749 different case in order to build the required database for ANN training. Two different algorithm input to train ANN with one hidden layer and one output layer using different number of nodes are modeled in MATLAB. The results performance is continuously compared and evaluated till acceptable Regression is achieved to insure the error is less than +/-1.5%. The high frequency due to switching-on the transmission line is also recorded and analyzed. The results show that this new method is efficient, accurate and useful as there is no cable monitoring system is available for each HV cable installed within the transmission line.
Analysis of the Coping Strategies of Primary Health Care Professionals: Cross-Sectional Study in a Large Brazilian Municipality
Authors: Lourenção Luciano Garcia , Rigino Bruno Martinez , Sasaki Natalia Sperli Geraldes Marin dos Santos , Pinto Maria Jaqueline Coelho , Ximenes Neto Franciso Rosemiro Guimarães , Melo Flávio Adriano Borges , Santos Maria de Lourdes Sperli Geraldes , Penha José Gustavo Monteiro , Galvão Daniela Menezes , Santos Betânia Maria Pereira dos , Cunha Isabel Cristina Kowal Olm , Oliveira Jacqueline Flores de , Afonso Max dos Santos , Cunha Carlos Leonardo Figueiredo , Silva Francielle Garcia da , Freire Neyson Pinheiro , Nascimento Vagner Ferreira do , Rodrigues Sidiane Teixeira , Carvalho Taisa Moitinho de , Lemos Messias , Cunha Juliana Lima da , Domingos Neide Aparecida Micelli
Published: February 2022

The aim was to analyze the coping strategies used by primary health care (PHC) professionals. A cross-sectional, descriptive-analytical study was conducted with professionals working in primary health care units in São José do Rio Preto, a large city in the interior of São Paulo, Brazil. For data collection we used an instrument developed by the researchers, containing sociodemographic and professional variables, as well as the Problem Coping Modes Scale (EMEP). We evaluated 333 PHC professionals. A difference was observed between the scores of the four coping strategies (p<0.001), with the highest score for the problem-focused strategy (3.8) and the lowest score for the emotion-focused strategy (2.4). Physicians had the lowest scores in coping strategies focused on religious practices/fantastical thinking (p<0.001) and pursuit of social support (p=0.045), while community health agents had the highest scores in these coping strategies). Professionals working in PHC have different coping strategies for the problems and stressful situations experienced in the work environment. These strategies can involve more positive attitudes focused on confrontation and problem solving, to emotional responses that involve attitudes of avoidance and denial that involve attitudes of avoidance and denial of the problem.
Polymeric Surfactant P84/Polyoxometalate α-PW12O403-—A Model System to Investigate the Interplay Between Chaotropic and Hydrophobic Effects
Authors: Schmid Philipp , Grass Xaver , Bahadur Pratap , Grillo Isabelle , Diat Olivier , Pfitzner Arno , Bauduin Pierre
Published: February 2022

Low charge density nanometric ions were recently shown to bind strongly to neutral hydrated matter in aqueous solution. This phenomenon, called (super-)chaotropic effect, arises from the partial dehydration of both, the nano-ion and the solute, leading to a high gain in enthalpy. Here, we investigate the chaotropic effect of the polyoxometalate α-PW12O403- on the triblock copolymer P84: (EO)19(PO)43(EO)19 with (EO)19 the polyethoxylated and (PO)43 the polypropoxylated chains. The combination of phase diagrams, spectroscopic (nuclear magnetic resonance) and scattering (small angle neutron/X-ray scattering) techniques reveals that (i) below the micellization temperature of P84, PW12O403- exclusively binds to the propylene oxide moiety of P84 unimers and (ii) above the micellization temperature, PW12O403- mostly adsorbs on the ethylene oxide micellar corona. The preferential binding of the PW12O403- to the PPO chain over the PEO chains suggests that the binding is driven by the chaotropic effect and reinforced by the hydrophobic effect. At higher temperatures, the copolymer micellization leads to the displacement of PW12O403- from the PPO chain to the PEO chains. This study deepens the understanding of the subtle interplay between the chaotropic and hydrophobic effects in complex salt-organic matter solutions.
Comparison of the Strength of Biodegradation of Pyrene between Symbiont Bacteria of Marine Sponges and Bacteria Isolated from Seawater
Authors: Marzuki Ismail , Nisaa Khairun , Asaf Ruzkiah , Paena Mudian , Athirah Admi , Susianingsih Endang , Nurhidayah Nurhidayah , Kadriah Ince Ayu Khairana , Kamaruddin Kamaruddin , Sahabuddin Sahabuddin , Nurbaya Nurbaya , Septiningsih Early , Herlinah Herlinah , Hendrajat Erfan Andi , Suwardi Suwardi , Ramlan Andi
Published: February 2022

PAHs contaminants have toxic, carcinogenic, and even mutagenic properties. Screening bacteria from different sources capable of carrying out the biodegradation of PAHs is important for mapping and mobilization purposes and applying them to polluted hydrocarbon environments. The study aimed to compare the biodegradation power of two types of bacteria isolated from different sources against PAHs. The method applied is the interaction between bacterial suspension and pyrene contaminated waste for 30 days. Biodegradation products in organic compounds were analyzed using GC-MS and FTIR. The analysis results found several indications of the performance of bacterial biodegradation, namely: the aggressiveness of biodegradation of Bl bacteria against pyrene was relatively more dominant than Sb bacteria. Percentage of total bacterial biodegradation product type Sb (39.00 %), while the product of bacterial degradation type Bl (38.29 %); the biodegradation products of the test bacteria (Bl and Sb) were relatively similar to pyrene, in the form of alcohol and carboxylic acid organic compounds. It was concluded that there was no significant difference in biodegradation performance between Bl and Sb bacteria on pyrene. Both types of bacterial isolates from different sources can carry out the function of biodegradation of Pyrene.
Natural Dye from Kepok Banana Leaf Stalk on Cotton Fabric with Variation of Fixation
Authors: Ihsan Taufik , Saputro Sulistyo , Mahardiani Lina
Published: February 2022

The purposes of this study are to apply the natural dye obtained from Musa paradisiaca Var. Balbisiana Colla leaf stalk on cotton fabric with variation of fixation. The experiment was carried out by several steps including extraction of natural dye, mordanting process, dyeing process, fixation process and testing the application of natural dye on cotton fabric. The application testing was evaluated based on the color fastness againts washing and rubbing, color changes with gray scale and color staining with stainning scale. The results of this study show that extract of natural dye from Musa paradisiaca Var. Balbisiana Colla leaf stalk is applicable as natural dye in textile. Moreover, using fixation can increase the color fastness in which alum 10 g/L provided the best color fastness, ie scale 3-4 (good enough) for color fastness againts washing and dry rubbing, and 4 (good) for wet rubbing.
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF CERTAIN 1,2,4-TRIAZOLE DERIVATIVES
Authors:   Raghavendra Guru Prasad Aluru, Rao Desabattina Venkata Narayana
Published: February 2022

A new class of 1,2,4-triazole derivatives namely 3-(3,4-substituted-phenyl)-4-(4-fluoro-phenyl)-5-methyl-4H-1,2,4-triazoles (6a-6h) were synthesized. The structure of each novel compound was elucidated on the basis of elemental analysis, IR and 1H NMR spectral data. The pharmacological properties of 1,2,4-triazoles were enhanced by introducing alkyl, alkoxy and halogen substituents. The minimum inhibitory concentration was evaluated by broth dilution method. As predicted and as evidenced in the literature, the halogen substituted compounds were found to be better antimicrobial agents.
FREQUENCY OF INTESTINAL WORM INFESTATION AMONG SCHOOL GOING CHILDREN IN KARACHI-PAKISTAN.
Authors:   Rehman Ullah Khan, Khan Sherwani Sikandar
Published: February 2022

In this study, the result findings of the current study indicated that out of 216 children including 120 male children and 96 female children participated in the study, 167 children were found positive with various intestestinal worms. The frequency of worm infestation was found 77.31%. Among them the positive worm infestation was more in female children (64%). Out of 167 positive subjects, Ascaris lumbricoides frequency 53.29% was highest among all other worms and was present in both single and mixed infestations. Similarly, a bit high frequency was also noted in case of for Hymenolepis nana 20%, Trichuris trichura 10% and lowest frequency was noted in Taenia saginata (0.59%).
T.C. Sağlık Bakanlığı’nın Mobil Sağlık Uygulamalarının Bilinirliğine Yönelik Bir Araştırma
Authors: YAYLA Elif Nisa , ÇİZMECİ Bülent
Published: February 2022

Günümüz mobil sağlık pazarı incelendiğinde her yaşa ve ihtiyaca göre geliştirilen uygulamalar bulunabilmektedir. Mevcut bu çalışma kapsamında değişime ve gelişime ayak uyduran T.C. Sağlık Bakanlığı’nın vatandaşlar için geliştirdiği m-Sağlık uygulamaların bilinirliği, kullanım amaçları ve sıklığının değerlendirilmesi amaçlanmaktadır. Türkiye’de ikamet eden ve mobil cihaz kullanan kişiler arasından kolayda örneklem yöntemi ile 1.078 katılımcıya ulaşılmıştır. Veri toplama aracı olarak kullanılan anketler 18-31 Ocak 2021 tarihinde online olarak gerçekleştirilmiş ve yalnız kullanılabilir olanları çalışmaya dahil edilerek SPSS Paket Programı ile analiz edilmiştir. Araştırmanın Cronbach’ Alpha Değeri 0,757 olarak saptanmıştır. Katılımcıların %28,8’inin ayda en az bir defa uygulamaları kullandığı, %60,8’inin internet aracılığı ile kullanımından haberdar olduğu, %93’ünün cep telefonu aracılığı ile kullandığı, %97,6’sının ise tanıdıklarına tavsiye ettiği görülmektedir. Uygulamaların haberdar olma ve kullanma durumları ele alındığında e-Nabız, MHRS, Hayat Eve Sığar ve Şehir Hastaneleri mobil uygulamaları dışındaki diğer uygulamaların oranlarının daha düşük olduğu sonucu saptanmıştır. M-Sağlık araçlarının bilinirliği ve kullanım oranları göz önüne alındığında bu araçların ihtiyaç tespiti, geliştirilmesi ve tanıtım faaliyetleri, kullanım sorunlarının tespit edilmesi ve etkin kullanımları için sağlık okuryazarlığına yönelik olarak yeni araştırmalar yapılması önerilmektedir. m-Sağlık araçlarına yönelik olarak yapılan ilk ve kapsamlı çalışmamızın sonuçları göz önünde bulundurularak uygulamalarının teorik, uygulama ve yönetimsel açıdan geliştirilmesi noktasında literatüre önemli katkılar sağlayacağı düşünülmektedir.
Akademisyenlerin Sağlık Anksiyeteleri İle Siberkondri Düzeyleri Arasındaki İlişkinin İncelenmesine Yönelik Bir Araştırma
Authors: ÖZYILDIZ Kevser Hüsna , ALKAN Ahmet
Published: February 2022

Bu çalışma akademisyenlerin internetten sağlık ve sağlık bilgisi arama davranışları (siberkondri) ile sağlık anksiyeteleri arasındaki ilişkinin incelenmesi amacıyla yapılmıştır. Araştırmanın katılımcıları yaşları 23 ile 66 arasında değişen (Ortyaş=37,34, SSyaş=8,403) 289 öğretim elemanından oluşmaktadır. Araştırma verileri Siberkondri Ciddiyet Ölçeği Kısa Formu (SCÖ-15), Sağlık Anksiyetesi Ölçeği ve demografik bilgilerin yer aldığı anket formu ile toplanmıştır. Ölçeklerin boyutları normal dağılıma uygunluk gösterdiği için boyutlar çeşitli değişkenlere göre karşılaştırılırken ikili gruplarda t testi (independent t test), üç ve daha fazla değişkenli gruplarda ise ANOVA (F testi) kullanılmıştır. Akademisyenlerin siberkondri düzeyleri ve sağlık anksiyeteleri arasındaki ilişki ise korelasyon analizi ile ortaya konulmuştur. Çalışma sonucunda sağlık anksiyetesi gövde boyutu ile SCÖ zorlantı, aşırı kaygı, aşırılık ve içini rahatlatma boyutları arasında; sağlık anksiyetesi olumsuz sonuç boyutu ile SCÖ zorlantı, aşırı kaygı ve doktora güvensizlik boyutları arasında pozitif yönde anlamlı bir ilişki olduğu ortaya konulmuştur.
SKENARIO PERTUMBUHAN EKONOMI PASCA COVID-19 DI TULUNGAGUNG
Authors: Nurohman Dede , Aziz Abd , Fahmi Moh. Farih
Published: February 2022

Dampak COVID-19 sangat terasa terlebih sektor ekonomi. Upaya pemerintah dalam menghadapi virus ini mulai pemberian stimulasi ekonomi hingga himbauan sosial dalam bentuk; social distancing, PSBB, larangan mudik, sampai new normal dimaksudkan agar keselamatan warga terjaga sekaligus sektor ekonomi tetap berjalan. Tulisan ini mengarahkan kajiannya pada bagaimana dampak ekonomi di Tulungagung dan langkah startegis apa yang seharusnya dilakukan. Pendekatan dalam penelitian ini adalah kualitatif berjenis library research dan bersifat inferential. Analisis data dilakukan dengan menggunakan content analysis. Literatur diambil dari berbagai sumber resmi, informasi, dan berita yang beredar secara online terkait ekonomi. Hasil penelitian menunjukkan bahwa di Tulungagung masih belum bisa digambarkan secara pasti kondisi ekonomi setelah masa pandemi. Namun, untuk mempertahankan pertumbuhan ekonominya, Tulungagung dapat mempertimbangkan dua skenario, skenario dengan PSBB dan tanpa PSBB. [The impact of COVID-19 is too felt especially in the economic sector. Government efforts in dealing with this virus began to provide economic stimulation to social appeals in the form of; social distancing, PSBB, prohibition of going home, until new normal poicy is intended so that the safety of citizens is maintained as well as the economic sector continuesly grows. This paper directs his study on how the economic impact in Tulungagung and what strategic steps should be taken. The approach in this research is qualitative research in library research type. Data analysis was performed using content analysis. The results showed that in Tulungagung still could not be described with certainty the economic conditions after the pandemic. However, to maintain economic growth, Tulungagung can consider two scenarios, a scenario with PSBB and without PSBB.]
PERSEPSI GURU TENTANG ISLAM RAHMATAN LIL ‘ALAMIN DAN DAMPAKNYA TERHADAP NASIONALISME PELAJAR
Authors: Susanto Susanto
Published: February 2022

Guru merupakan salah satu faktor kunci dalam pembentukan pembentukan sikap pelajar. Corak pemahaman keislaman yang dimiliki guru, umumnya tidak hanya diekspresikan dalam praktik teologis, namun mempengaruhi sikap dirinya dalam berbangsa dan bernegara serta proses transmisi kepada pelajar. Tujuan penelitian dalam artikel ini adalah untuk mendeskripsikan persepsi guru di Jawa Barat terkait konsep Islam berwawasan rahmatan lil ‘alamin serta dampak persepsi guru terhadap sikap nasionalisme pelajar di Provinsi Jawa Barat. Penelitian ini menggunakan metode penelitian kualitatif dengan teknik pengumpulan data melalui google form dan proses analisis data menggunakan analisis deskriptif. Responden guru dan pelajar berasal dari sekolah yang sama, berasal dari jenjang SMP dan SLTA di Jawa Barat. Penelitian terhadap persepsi guru terhadap konsepsi Islam berwawasan rahmatan lil alamiin dilihat  dari 3 aspek yaitu persepsi terhadap konsep teologis, urgensi penerapan dan manfaat. Adapun sikap nasionalisme pelajar dilihat dari tujuh indikator meliputi; bangga sebagai bangsa Indonesia, cinta tanah air dan bangsa, menerima dan menghargai kemajemukan, bangga pada budaya yang beraneka ragam, menghargaai jasa para pahlawan dan mengutamakan kepentingan bangsa. Hasil penelitian ini ditemukan bahwa mayoritas guru memiliki pandangan positif terhadap konsepsi Islam berwawasan rahmatan lil alamiin dan berdampak terhadap sikap nasionalisme pelajar. [The teacher is one of the key factors in shaping student attitudes. The style of Islamic understanding that the teacher has is generally not only expressed in theological practice, but affects his attitude in the nation and state as well as the process of transmission to students. The research objective in this article is to describe the perceptions of teachers in West Java regarding the concept of Islam with the insight of rahmatan lil 'alamin and the impact of teacher perceptions on the nationalism attitude of students in West Java Province. This research uses qualitative research methods with data collection techniques through google form and the data analysis process uses descriptive analysis. Teacher and student respondents come from the same school, come from the junior and senior high school levels in West Java. Research on teachers' perceptions of the Islamic concept with rahmatan lil alamin insight is seen from 3 aspects, namely perceptions of theological concepts, urgency of application and benefits. As for the attitude of student nationalism, seen from seven indicators, they are; proud to be the nation of Indonesia, love the country and the nation, accept and appreciate diversity, be proud of diverse cultures, value the services of heroes and put the interests of the nation first. The results of this study found that the majority of teachers have a positive view of the concept of Islam with the insight of rahmatan lil alamin and have an impact on the nationalism of students.]
Female Education and Maternal Health Care Utilization: Evidence from Uganda
Authors: Amwonya David , Kigosa Nathan , Kizza James
Published: February 2022

Background: Maternal health care Indicator Is among the key Indicators of population health, health economic development. Therefore, the study attempts to explore female education and maternal healthcare utilization in Uganda. The study identifies the causal effect of introduction of free education, by exploiting the age as an instrument at the second stage model. This instrument provides an exogenous source of variation in the years of schooling and allows to implement a regression discontinuity design, which accounts for heterogeneity in the cohort overtime. Methods: The study also uses the OLS to help predict years of schooling that are used in the second stage model in the 2SLS. The study further uses the RDD model with a running variable of birth years to observe its effect on education. To control heterogeneity in regions in the second stage model, a fixed effects model was used. Results: Female education indeed had a positive impact on maternal health care utilization. It was further found out that age also influences maternal health care utilization.Conclusions: Therefore, as an effort to improve professional maternal health care utilisation, there is need to focus on education beyond primary level. Government should also ensure that there is an improvement in community infrastructure and security across all regions and locations.
Validation of The Environmental Kuznets Curve Hypothesis And Role of Carbon Emission Policies In The Case of Russian Federation
Authors: Kilinc-Ata Nurcan , Likhachev Vladimir L.
Published: February 2022

Climate change currently observed and expected in the future is associated with risks to security and sustainable development as well as natural and irreversible consequences. To minimize these risks, it is necessary to adapt the public administration, economic sectors, and regional infrastructure to the changing climate conditions. This paper discovers the links between CO2 emission and their key determinants such as economic growth, energy consumption, population, trade openness, and financial development for the Russian Federation using data from 1990 through 2020. Findings reveal that energy consumption, and population have a positive impact on CO2 emissions, while economic growth, financial development, and trade openness has been found to decrease CO2 emissions in the long term. The results of the paper show that there is a "U" shaped relationship between CO2 emissions and economic growth in the Russian Federation. This shows that EKC is valid up to a certain income level in the Russian Federation and when this income level is exceeded, a positive relationship will begin between economic growth and environmental degradation.
Effect of Bovine Milk Fat-based Infant Formulae on Microbiota, Metabolites and Stool Parameters in Healthy Term Infants in A Randomized, Crossover, Placebo-controlled Trial
Authors: Looijesteijn Ellen , Brouwer Rutger W. W. , Schoemaker Ruud J. W. , Ulfman Laurien H. , Ham Stephanie L. , Jeurink Prescilla , Karaglani Eva , IJcken Wilfred F. J. , Manios Yannis
Published: February 2022

Background: Natural enrichment of sn-2 palmitate content of infant formulae by using bovine milk fat is known to reduce faecal fatty acid soap formation and improve stool consistency, but effects on gut microbiota composition are unknown. The purpose of this study was to test the influence of milk fat-based formula high in sn-2 palmitate on the infants’ gut microbiota composition and to confirm the beneficial effects of the formula on faecal composition and stool consistency. Methods: Twenty-two healthy term, formula-fed infants were enrolled in a single-blinded randomized, crossover, placebo-controlled trial. After a 2 week run in period, infants received either a 50% milk fat-based formula containing 39% sn-2 palmitate (MF) or a vegetable fat-based formula (VF) containing 10% sn-2 palmitate in a 2x2 week crossover design. Faecal microbiota composition was the primary outcome of the study. Other outcomes included faecal fatty acid soap excretion, calcium excretion, gut comfort parameters and faecal metabolites. Results: Microbiota analysis showed that bifidobacteria dominated the gut microbiota of most infants. Neither alpha- nor beta-diversity was significantly influenced by the intervention. The MF formula resulted in significantly lower faecal levels of palmitic acid soap and total fatty acid soaps than the VF formula (p<0.0002). Additionally, calcium excretion and palmitic acid concentration were significantly (p<0.05) lower in stool samples after MF intervention. Furthermore, a significant physiological effect on softer stools was observed in the MF intervention compared to the VF intervention (p=0.02). Of the 870 measured faecal metabolites, 263 were significantly different after MF and VF intervention (p<0.05). Most of these were found at higher levels after MF intervention, potentially indicative of the complex structure of milk fat. Metabolites with more than 2-fold change between interventions were mostly lipid-derived and included several milk fat-specific fatty acids. Conclusions: Replacing part of the vegetable fat in infant formula with bovine milk fat with high sn-2 palmitate levels did not change the microbiota composition, although a reduction in faecal palmitate soaps, total fatty acid soaps and calcium excretion while improving stool consistency in the MF intervention was confirmed. In addition, 263 faecal metabolites were significantly different, many related to the fat source. Trial registration: Netherlands Trial Registry Identifier: NL7815 19/06/2019
Arabidopsis Oil Body-Expressed Oleosin-rhFGF5 Inhibits Hair Growth in Mouse
Authors: Wang Hongyu , Noman Muhammad
Published: February 2022

As a member of the fibroblast growth factor family, FGF5 can regulate hair growth, promote injury repair and the development of the body. The expression of exogenous recombinant human FGF5 protein in Arabidopsis by transgenic technology is of great significance to explore its potential mechanism of action and clinical application in the future. We constructed the pOTB-rhFGF5 oil body fusion expression vector and transformed into Arabidopsis. The transgenic Arabidopsis was identified by PCR, SDS-PAGE and Western blot. The pharmacological activity of the recombinant oleosin-rhFGF5 protein in hair growth inhibition was tested in vitro as well as in vivo. PCR assay, SDS-PAGE and western blot showed that the recombinant human FGF5 gene was stably inherited and expressed in Arabidopsis, and the target protein size was 47 kDa. Moreover, our experiments showed that the 12.5 ng/mL oleosin-rhFGF5 began to inhibit the proliferation of hair follicle epithelial cell, the inhibition effect was proportional to the dose. In vivo activity studies also showed that the oleosin-rhFGF5 had the activity of inhibiting hair regeneration. We successfully transformed the recombinant human FGF5 gene into Arabidopsis and expressed the target protein olesoin-rhFGF5 in Arabidopsis. The recombinant protein olesoin-rhFGF5 has hair regeneration inhibition activity both in vivo and vitro.
Serum potassium trajectory during AKI and mortality risk
Authors: Chávez-Iñiguez Jonathan , Maggiani-Aguilera Pablo , de Quevedo Andrés Aranda-García , Granado Rolando Claure-Del , Vega-Vega Olynka , López-Giacoman Salvador R. , Chávez-Alonso Gael , Oliva-Martínez Ana E. , Díaz-Villavicencio Bladimir , Calderón-García Clementina E. , González-Barajas David , Arizaga-Nápoles Manuel , Vega-Méndez Frida M. De la , Navarro-Blackaller Guillermo , Medina-González Ramón , Ibarra-Hernández Margarita , Garcia-Garcia Guillermo
Published: February 2022

Background: Kidneys play a primary role in potassium homeostasis. The association between potassium (sK+) level and mortality or the need for kidney replacement therapy (KRT) during acute kidney injury (AKI) has not been adequately explored. Methods: In this prospective cohort study, AKI patients admitted to the Hospital Civil de Guadalajara were enrolled from August 2017 to June 2021 with AKI. We divided patients into 8 groups based on the serum potassium level trajectories up to ten days following hospitalization, (1) normokalemia (normoK), defined as sK+ values between 3.5 and 5.5 mEq/L; (2) corrected hyperkalemia (hyperK), sK+ > 5.5 mEq/L on hospital admission and decreased to normoK; (3) corrected hypokalemia (hypoK), sK+ < 3.5 mEq/L on hospital admission and increased to normoK; (4) fluctuating potassium, sK+ increased / decreased in and out of normoK parameters; (5) uncorrected hypoK, sK+ < 3.5 mEq/L; (6) normoK to hypoK, sK+ that were normal on hospital admission and decreased to hypoK and never went back to normal; (7) normoK to hyperK, sK+ that were normal on hospital admission and increased to hyperK and never went back to normal; (8) uncorrected hyperK, sK+ > 5.5 mEq/L. We assessed the association of serum potassium trajectories with mortality and the need for KRT (secondary objective). Results: A total of 311 AKI patients were included. The mean age was 52.6 years, and 182 (58.6%) were male. AKI stage 3 was present in 199 (63.9%). KRT started in 112 (36%) patients, and 66 (21.2%) died. After adjusting for confounders, 10-day hospital mortality was significantly higher in group 7 and 8 (OR, 1.37 and 1.63, p = <0.05, for both, respectevely), and KRT initiation was higher only in group 8 (OR 1.40, p = < 0.05) compared with group 1. Mortality in different subgroups of patients in group 8 did not change the primary results.Conclusion: In our prospective cohort, most patients with AKI had alterations in sK+. NormoK to hyperK and Uncorrected hyperK were associated with death, while only uncorrected hyperK was correlated with the need for KRT.
The clinical implications of pre-liver transplant diabetes on post-liver transplant outcomes in patients with NASH: analysis of the UNOS database
Authors: Lee David Uihwan Uihwan , Han John , Lee Ki Jung , Kwon Jean , Fan Gregory Hongyuan , Jung Daniel , Urrunaga Nathalie Helen
Published: February 2022

Background & Aims: The presence of perioperative diabetes may lead to increased mortality risks following liver transplant (LT) in patients with non-alcoholic steatohepatitis (NASH). This risk factor was evaluated using a UNOS-STAR national database. Methods: The UNOS-STAR liver transplant registry 2005-2019 was used to select patients with NASH (including cryptogenic liver disease). The following populations were excluded: those younger than 18 years old and those with living donors/dual transplants. Selected patients were stratified into those with and without pre-LT diabetes and compared to the individual mortality endpoints using iterative Cox analyses. Results: 6324 recipients with and 8251 without diabetes were selected. The median follow-up time was 3.07 years. Those with diabetes were older (58.50 vs. 54.50 years, p<0.001), were more likely to be Hispanic or Asian, and had higher BMI than the non-diabetics (31.10 vs. 29.70 kg/m² p<0.001); however, there was no difference in gender (female 41.9 vs. 43.1% p=0.170). Compared to non-diabetics, recipients with diabetes had a higher rate of all-cause mortality (61.68 vs. 47.80 per 1000 person-years). In multivariate iterations, pre-LT diabetes was associated with all-cause mortality (aHR 1.19 95% CI 1.11-1.27) as well as deaths due to cardiac (p=0.014 aHR 1.24 95% CI 1.04-1.46) and renal causes (p=0.039 aHR 1.38 95% CI 1.02-1.87). Conclusion: The presence of pre-LT diabetes is associated with all-cause mortality and deaths due to cardiac and renal causes following LT. The findings warrant an early preoperative screening procedure to ensure that patients with diabetes have their metabolic risk factors optimized prior to LT.
Multi-criteria comparative analysis of the pressure drop on coal gangue fly-ash slurry at different parts along an L-shaped pipeline
Authors: Wang Defeng , Jiao Dengwu , Cheng Zhanbo , Shi Qingwen , Mischo Helmut
Published: February 2022

Disposing coal gangue and fly-ash on the surface is a risky method which has tremendous potential catastrophic consequences for the environment, whereas backfill mining is a promising practice turing those hazardous wastes into useful backfill materials. Unfortunately, how to deliver the slurry into avoid efficiently remains underresearched, therefore, to address this gap, in the present paper, in addition to a laboratory rheological test, computational fluid dynamics software Fluent was also employed to simulate the different effects that individual variables have on the pressure evolution at a specific section of the pipeline. Furthermore, the response surface method was implemented to examine how the multiple factors synergistically affect the pressure drop and their corresponding influencing weights. This paper shows that slurry concentration, speed, and pipe diameter all significantly affect the pressure drop of slurry and that conveying speed is the dominant factor in the bend section. In contrast, pipe diameter becomes the dominant factor in the horizontal and vertical pipe sections.
A CNN-based Lower Limb Motion Quality Evaluation Method for Home-based Stroke Rehabilitation
Authors: Ge Pin , Huang Ziyang , Tang Guoliang , Kumar Akshay , Mahmoud Seeahmed , Fang Qiang , Chen Jian
Published: February 2022

Background: With the rapid increase of stroke incidence in recent years worldwide, home-based rehabilitation training has become more needed, especially for remote regions or in developing countries where rehabilitation resources are scarce. Studies have demonstrated that home-based rehabilitation for poststroke patients is essential for reducing the cost as well as for providing efficient rehabilitation. Nevertheless, home-based rehabilitation training requires effective professional support and timely evaluation. Method: In this paper, a home-based rehabilitation quality evaluation method for lower limb training was proposed. The kinematic data of a patient’s lower limb during a set of selected training exercises was captured by a wireless body area sensor network (WBASN). The data was then processed by a convolutional neural network (CNN) based algorithm to classify the rehabilitation training type and to evaluate the training quality. A series of kinematic features were selected for rehabilitation quality scoring. The experiments have been conducted using 26 human participants, including 6 healthy participants and 20 stroke patients at different Brunnstrom recovery stages. Results: An accuracy of 95.3% has been achieved for recognizing the rehabilitation training types and a statistically significant positive correlation has been obtained between the objective scores and the Brunnstrom stages evaluated by the clinicians.