bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 9 from Detection and Characterization of a Novel Subset of CD8+CD57+ T Cells in Metastatic Melanoma with an Incompletely Differentiated Phenotype
Authors: Wu Richard C. , Liu Shujuan , Chacon Jessica A. , Wu Sheng , Li Yufeng , Sukhumalchandra Pariya , Murray James L. , Molldrem Jeffrey J. , Hwu Patrick , Pircher Hanspeter , Lizée Gregory , Radvanyi Laszlo G.
Published: April 2023

PDF file - 117K, CD8+CD57+ T cells in TIL can further differentiate into CD27-CD57+, Perfhigh effector cells ex vivo.
Supplementary Figure 8 from Detection and Characterization of a Novel Subset of CD8+CD57+ T Cells in Metastatic Melanoma with an Incompletely Differentiated Phenotype
Authors: Wu Richard C. , Liu Shujuan , Chacon Jessica A. , Wu Sheng , Li Yufeng , Sukhumalchandra Pariya , Murray James L. , Molldrem Jeffrey J. , Hwu Patrick , Pircher Hanspeter , Lizée Gregory , Radvanyi Laszlo G.
Published: April 2023

PDF file - 106K, The CD8+CD27+CD57+ subset in melanoma TIL was not anergic and could be induced to produce a high level of IFN-g and other Th2 cytokines after TCR stimulation with CD28 co-stimulation.
Supplementary Table 5 from High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway
Authors: Yoshihara Kosuke , Tsunoda Tatsuhiko , Shigemizu Daichi , Fujiwara Hiroyuki , Hatae Masayuki , Fujiwara Hisaya , Masuzaki Hideaki , Katabuchi Hidetaka , Kawakami Yosuke , Okamoto Aikou , Nogawa Takayoshi , Matsumura Noriomi , Udagawa Yasuhiro , Saito Tsuyoshi , Itamochi Hiroaki , Takano Masashi , Miyagi Etsuko , Sudo Tamotsu , Ushijima Kimio , Iwase Haruko , Seki Hiroyuki , Terao Yasuhisa , Enomoto Takayuki , Mikami Mikio , Akazawa Kohei , Tsuda Hitoshi , Moriya Takuya , Tajima Atsushi , Inoue Ituro , Tanaka Kenichi
Published: April 2023

PDF file - 648K
Supplementary Figure 4 from Detection and Characterization of a Novel Subset of CD8+CD57+ T Cells in Metastatic Melanoma with an Incompletely Differentiated Phenotype
Authors: Wu Richard C. , Liu Shujuan , Chacon Jessica A. , Wu Sheng , Li Yufeng , Sukhumalchandra Pariya , Murray James L. , Molldrem Jeffrey J. , Hwu Patrick , Pircher Hanspeter , Lizée Gregory , Radvanyi Laszlo G.
Published: April 2023

PDF file - 90K, Summary of CD27 and CD28 expression in the CD8+ TIL subsets (n=39) and in the CD8+MART-1+ TIL subset (n=11) of metastatic melanoma showing a lack of CD27-CD28- fully differentiated T cells and the preponderance of CD27+CD28+ TEM.
Supplementary Table 4 from High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway
Authors: Yoshihara Kosuke , Tsunoda Tatsuhiko , Shigemizu Daichi , Fujiwara Hiroyuki , Hatae Masayuki , Fujiwara Hisaya , Masuzaki Hideaki , Katabuchi Hidetaka , Kawakami Yosuke , Okamoto Aikou , Nogawa Takayoshi , Matsumura Noriomi , Udagawa Yasuhiro , Saito Tsuyoshi , Itamochi Hiroaki , Takano Masashi , Miyagi Etsuko , Sudo Tamotsu , Ushijima Kimio , Iwase Haruko , Seki Hiroyuki , Terao Yasuhisa , Enomoto Takayuki , Mikami Mikio , Akazawa Kohei , Tsuda Hitoshi , Moriya Takuya , Tajima Atsushi , Inoue Ituro , Tanaka Kenichi
Published: April 2023

PDF file - 586K
Supplementary Table 3 from High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway
Authors: Yoshihara Kosuke , Tsunoda Tatsuhiko , Shigemizu Daichi , Fujiwara Hiroyuki , Hatae Masayuki , Fujiwara Hisaya , Masuzaki Hideaki , Katabuchi Hidetaka , Kawakami Yosuke , Okamoto Aikou , Nogawa Takayoshi , Matsumura Noriomi , Udagawa Yasuhiro , Saito Tsuyoshi , Itamochi Hiroaki , Takano Masashi , Miyagi Etsuko , Sudo Tamotsu , Ushijima Kimio , Iwase Haruko , Seki Hiroyuki , Terao Yasuhisa , Enomoto Takayuki , Mikami Mikio , Akazawa Kohei , Tsuda Hitoshi , Moriya Takuya , Tajima Atsushi , Inoue Ituro , Tanaka Kenichi
Published: April 2023

PDF file - 302K
Supplementary Table 2 from High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway
Authors: Yoshihara Kosuke , Tsunoda Tatsuhiko , Shigemizu Daichi , Fujiwara Hiroyuki , Hatae Masayuki , Fujiwara Hisaya , Masuzaki Hideaki , Katabuchi Hidetaka , Kawakami Yosuke , Okamoto Aikou , Nogawa Takayoshi , Matsumura Noriomi , Udagawa Yasuhiro , Saito Tsuyoshi , Itamochi Hiroaki , Takano Masashi , Miyagi Etsuko , Sudo Tamotsu , Ushijima Kimio , Iwase Haruko , Seki Hiroyuki , Terao Yasuhisa , Enomoto Takayuki , Mikami Mikio , Akazawa Kohei , Tsuda Hitoshi , Moriya Takuya , Tajima Atsushi , Inoue Ituro , Tanaka Kenichi
Published: April 2023

PDF file - 292K
Supplementary Materials and Methods from High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway
Authors: Yoshihara Kosuke , Tsunoda Tatsuhiko , Shigemizu Daichi , Fujiwara Hiroyuki , Hatae Masayuki , Fujiwara Hisaya , Masuzaki Hideaki , Katabuchi Hidetaka , Kawakami Yosuke , Okamoto Aikou , Nogawa Takayoshi , Matsumura Noriomi , Udagawa Yasuhiro , Saito Tsuyoshi , Itamochi Hiroaki , Takano Masashi , Miyagi Etsuko , Sudo Tamotsu , Ushijima Kimio , Iwase Haruko , Seki Hiroyuki , Terao Yasuhisa , Enomoto Takayuki , Mikami Mikio , Akazawa Kohei , Tsuda Hitoshi , Moriya Takuya , Tajima Atsushi , Inoue Ituro , Tanaka Kenichi
Published: April 2023

PDF file - 81K
Related Article from Blinded by the Light: Molecular Imaging in Pancreatic Adenocarcinoma
Authors: Collisson Eric , Tempero Margaret
Published: April 2023

Related Article from Blinded by the Light: Molecular Imaging in Pancreatic Adenocarcinoma
Supplementary Figure 2 from High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway
Authors: Yoshihara Kosuke , Tsunoda Tatsuhiko , Shigemizu Daichi , Fujiwara Hiroyuki , Hatae Masayuki , Fujiwara Hisaya , Masuzaki Hideaki , Katabuchi Hidetaka , Kawakami Yosuke , Okamoto Aikou , Nogawa Takayoshi , Matsumura Noriomi , Udagawa Yasuhiro , Saito Tsuyoshi , Itamochi Hiroaki , Takano Masashi , Miyagi Etsuko , Sudo Tamotsu , Ushijima Kimio , Iwase Haruko , Seki Hiroyuki , Terao Yasuhisa , Enomoto Takayuki , Mikami Mikio , Akazawa Kohei , Tsuda Hitoshi , Moriya Takuya , Tajima Atsushi , Inoue Ituro , Tanaka Kenichi
Published: April 2023

PDF file - 213K
Supplementary Figure 1 from Local Delivery of lnterleukin-12 Using T Cells Targeting VEGF Receptor-2 Eradicates Multiple Vascularized Tumors in Mice
Authors: Chinnasamy Dhanalakshmi , Yu Zhiya , Kerkar Sid P. , Zhang Ling , Morgan Richard A. , Restifo Nicholas P. , Rosenberg Steven A.
Published: April 2023

PDF file - 365K
Supplementary Figure 5 from Mitoxantrone Inhibits HIF-1α Expression in a Topoisomerase II–Independent Pathway
Authors: Toh Yng-Miin , Li Tsai-Kun
Published: April 2023

PDF file - 270K
Supplementary Table 1 from Proximal Fluid Proteome Profiling of Mouse Colon Tumors Reveals Biomarkers for Early Diagnosis of Human Colorectal Cancer
Authors: Fijneman Remond J.A. , de Wit Meike , Pourghiasian Maral , Piersma Sander R. , Pham Thang V. , Warmoes Marc O. , Lavaei Mehrdad , Piso Chloe , Smit Fiona , Delis-van Diemen Pien M. , van Turenhout Sietze T. , Terhaar sive Droste Jochim S. , Mulder Chris J.J. , Blankenstein Marinus A. , Robanus-Maandag Els C. , Smits Ron , Fodde Riccardo , van Hinsbergh Victor W.M. , Meijer Gerrit A. , Jimenez Connie R.
Published: April 2023

XLS file - 37K
Supplementary Table 6 from Integrative Genomics Identified RFC3 As an Amplified Candidate Oncogene in Esophageal Adenocarcinoma
Authors: Lockwood William W. , Thu Kelsie L. , Lin Lin , Pikor Larissa A. , Chari Raj , Lam Wan L. , Beer David G.
Published: April 2023

PDF file - 206K
Supplementary Figure Legends 1-3 from Proximal Fluid Proteome Profiling of Mouse Colon Tumors Reveals Biomarkers for Early Diagnosis of Human Colorectal Cancer
Authors: Fijneman Remond J.A. , de Wit Meike , Pourghiasian Maral , Piersma Sander R. , Pham Thang V. , Warmoes Marc O. , Lavaei Mehrdad , Piso Chloe , Smit Fiona , Delis-van Diemen Pien M. , van Turenhout Sietze T. , Terhaar sive Droste Jochim S. , Mulder Chris J.J. , Blankenstein Marinus A. , Robanus-Maandag Els C. , Smits Ron , Fodde Riccardo , van Hinsbergh Victor W.M. , Meijer Gerrit A. , Jimenez Connie R.
Published: April 2023

PDF file - 53K
Supplementary Methods, Tables 1-4, Figure Legends 1-9 from Integrative Genomics Identified RFC3 As an Amplified Candidate Oncogene in Esophageal Adenocarcinoma
Authors: Lockwood William W. , Thu Kelsie L. , Lin Lin , Pikor Larissa A. , Chari Raj , Lam Wan L. , Beer David G.
Published: April 2023

PDF file - 209K
Supplementary Materials and Methods from Protein Kinase CK2 Protects Multiple Myeloma Cells from ER Stress–Induced Apoptosis and from the Cytotoxic Effect of HSP90 Inhibition through Regulation of the Unfolded Protein Response
Authors: Manni Sabrina , Brancalion Alessandra , Tubi Laura Quotti , Colpo Anna , Pavan Laura , Cabrelle Anna , Ave Elisa , Zaffino Fortunato , Di Maira Giovanni , Ruzzene Maria , Adami Fausto , Zambello Renato , Pitari Maria Rita , Tassone Pierfrancesco , Pinna Lorenzo A. , Gurrieri Carmela , Semenzato Gianpietro , Piazza Francesco
Published: April 2023

PDF file - 101K
Supplementary Figure 1C from Biologic and Clinical Activity of Tivozanib (AV-951, KRN-951), a Selective Inhibitor of VEGF Receptor-1, -2, and -3 Tyrosine Kinases, in a 4-Week-On, 2-Week-Off Schedule in Patients with Advanced Solid Tumors
Authors: Eskens Ferry A.L.M. , de Jonge Maja J.A. , Bhargava Pankaj , Isoe Toshiyuki , Cotreau Monette M. , Esteves Brooke , Hayashi Kunihiko , Burger Herman , Thomeer Maarten , van Doorn Leni , Verweij Jaap
Published: April 2023

PDF file - 137K
Supplementary Figure 1A from Biologic and Clinical Activity of Tivozanib (AV-951, KRN-951), a Selective Inhibitor of VEGF Receptor-1, -2, and -3 Tyrosine Kinases, in a 4-Week-On, 2-Week-Off Schedule in Patients with Advanced Solid Tumors
Authors: Eskens Ferry A.L.M. , de Jonge Maja J.A. , Bhargava Pankaj , Isoe Toshiyuki , Cotreau Monette M. , Esteves Brooke , Hayashi Kunihiko , Burger Herman , Thomeer Maarten , van Doorn Leni , Verweij Jaap
Published: April 2023

PDF file - 100K
Supplementary Figure 1 from Biologic and Clinical Activity of Tivozanib (AV-951, KRN-951), a Selective Inhibitor of VEGF Receptor-1, -2, and -3 Tyrosine Kinases, in a 4-Week-On, 2-Week-Off Schedule in Patients with Advanced Solid Tumors
Authors: Eskens Ferry A.L.M. , de Jonge Maja J.A. , Bhargava Pankaj , Isoe Toshiyuki , Cotreau Monette M. , Esteves Brooke , Hayashi Kunihiko , Burger Herman , Thomeer Maarten , van Doorn Leni , Verweij Jaap
Published: April 2023

PDF file - 357K
Supplementary Figure 1 from Analyzing the Pivotal Trial That Compared Sunitinib and IFN-α in Renal Cell Carcinoma, Using a Method That Assesses Tumor Regression and Growth
Authors: Stein Wilfred D. , Wilkerson Julia , Kim Sindy T. , Huang Xin , Motzer Robert J. , Fojo Antonio Tito , Bates Susan E.
Published: April 2023

PDF file - 117K
Supplementary Table 9 from Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers
Authors: Reinert Thomas , Modin Charlotte , Castano Francisco M. , Lamy Philippe , Wojdacz Tomasz K. , Hansen Lise Lotte , Wiuf Carsten , Borre Michael , Dyrskjøt Lars , Ørntoft Torben F.
Published: April 2023

PDF file - 70K
Supplementary Table 4 from Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers
Authors: Reinert Thomas , Modin Charlotte , Castano Francisco M. , Lamy Philippe , Wojdacz Tomasz K. , Hansen Lise Lotte , Wiuf Carsten , Borre Michael , Dyrskjøt Lars , Ørntoft Torben F.
Published: April 2023

PDF file - 63K
Supplementary Figure 2 from Impact of the Integrin Signaling Adaptor Protein NEDD9 on Prognosis and Metastatic Behavior of Human Lung Cancer
Authors: Kondo Shunsuke , Iwata Satoshi , Yamada Taketo , Inoue Yusuke , Ichihara Hiromi , Kichikawa Yoshiko , Katayose Tomoki , Souta-Kuribara Akiko , Yamazaki Hiroto , Hosono Osamu , Kawasaki Hiroshi , Tanaka Hirotoshi , Hayashi Yuichiro , Sakamoto Michiie , Kamiya Kazunori , Dang Nam H. , Morimoto Chikao
Published: April 2023

PDF file - 110K, Gene transfer of NEDD9 renders NSCLC cells (PC-9 cells) chemoresistant
Supplementary Figure 6 from Ran Is a Potential Therapeutic Target for Cancer Cells with Molecular Changes Associated with Activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK Pathways
Authors: Yuen Hiu-Fung , Chan Ka-Kui , Grills Claire , Murray James T. , Platt-Higgins Angela , Eldin Osama Sharaf , O'Byrne Ken , Janne Pasi , Fennell Dean A. , Johnston Patrick G. , Rudland Philip S. , El-Tanani Mohamed
Published: April 2023

PDF file - 725K, Ran silencing-induced apoptosis depends on the growth stimulation in MDA MB231 and A549 cells using MTT assay.Percentage of cell survival in (A) MDA MB231 and (B) A549 cells expressing various levels of Ran grown in different conditions as determined by MTT assay. Results are plotted as histograms showing the mean � SD from three independent experiments. Key; *, ** and *** represent p < 0.05, <0.01 and <0.001, respectively.
Supplementary Figure 5 from Ran Is a Potential Therapeutic Target for Cancer Cells with Molecular Changes Associated with Activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK Pathways
Authors: Yuen Hiu-Fung , Chan Ka-Kui , Grills Claire , Murray James T. , Platt-Higgins Angela , Eldin Osama Sharaf , O'Byrne Ken , Janne Pasi , Fennell Dean A. , Johnston Patrick G. , Rudland Philip S. , El-Tanani Mohamed
Published: April 2023

PDF file - 1.3MB, Proliferation of MDA MB231 and A549 cells grown in different conditions.
Supplementary Figure 3 from Ran Is a Potential Therapeutic Target for Cancer Cells with Molecular Changes Associated with Activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK Pathways
Authors: Yuen Hiu-Fung , Chan Ka-Kui , Grills Claire , Murray James T. , Platt-Higgins Angela , Eldin Osama Sharaf , O'Byrne Ken , Janne Pasi , Fennell Dean A. , Johnston Patrick G. , Rudland Philip S. , El-Tanani Mohamed
Published: April 2023

PDF file - 1.6MB, Percentage of sub-G1 phase apoptotic MCF10a and MDA MB231 cells grown in serum-containing medium after Ran silencing. (A-B) Cells were infected with shRan1 and shRan2. Medium was changed to serum-free medium (DMEM) 24hr post-infection. Cells were harvested at 72hr and 96hr post-infection for (A) cell cycle and (B) Western blot analyses. (A) Significantly more sub-G1 phase cells were observed in MDA MB231 breast cancer cells than in immortalized breast epithelial cells 72 and 96 hr post-infection of the shRNAs. (B) More cleaved PARP, caspase 9 and caspase 3 were observed in MDA MB231 than in MCF10A cells upon Ran silencing, suggesting a higher apoptotic response in MDA MB231 than in MCF10a cells. Levels of Ran knockdown were similar in both cell lines. Actin was used as a loading control. (C-D) Cells were infected with shRan1 and shRan2, and harvested 72hr post-infection for (C) cell cycle and (D) Western blot analyses. (C) More apoptotic cells were observed in MDA MB231 than MCF10a cells upon Ran-silencing 72hr post-infection of shRNAs, when these two cell lines were grown in their normal medium. (D) Higher levels of cleaved PARP, caspase 9 and caspase 3 were observed at 72hr post-infection of shRNAs. Results are plotted as histogram showing the mean � SD from three independent experiments. Key; * represents p < 0.05 and ** represents p <0.01.
Supplementary Tables 1 - 2 from Comparison of Continuous versus Categorical Tumor Measurement–Based Metrics to Predict Overall Survival in Cancer Treatment Trials
Authors: An Ming-Wen , Mandrekar Sumithra J. , Branda Megan E. , Hillman Shauna L. , Adjei Alex A. , Pitot Henry C. , Goldberg Richard M. , Sargent Daniel J.
Published: April 2023

PDF file - 77KB, Table 1: Up to 16 Week Assessments adjusting for treatment arm and sum of baseline tumor measurements. Table 2: Up to 24 Week Assessments adjusting for treatment arm and sum of baseline tumor measurements.
Supplementary Figure 2 from Comparison of Continuous versus Categorical Tumor Measurement–Based Metrics to Predict Overall Survival in Cancer Treatment Trials
Authors: An Ming-Wen , Mandrekar Sumithra J. , Branda Megan E. , Hillman Shauna L. , Adjei Alex A. , Pitot Henry C. , Goldberg Richard M. , Sargent Daniel J.
Published: April 2023

PDF file - 12KB, Plots of observed versus expected 1-year survival probabilities for N9841 based on models for each metric and a model with no metric, adjusting for treatment arm and sum of baseline tumor measurements.
Supplementary Figure 1 from Comparison of Continuous versus Categorical Tumor Measurement–Based Metrics to Predict Overall Survival in Cancer Treatment Trials
Authors: An Ming-Wen , Mandrekar Sumithra J. , Branda Megan E. , Hillman Shauna L. , Adjei Alex A. , Pitot Henry C. , Goldberg Richard M. , Sargent Daniel J.
Published: April 2023

PDF file - 12KB, Plots of observed versus expected 1-year survival probabilities for N0026 based on models for each metric and a model with no metric, adjusting for treatment arm and sum of baseline tumor measurements.
Supplementary Figure Legends from Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells
Authors: Hudecek Michael , Lupo-Stanghellini Maria-Teresa , Kosasih Paula L. , Sommermeyer Daniel , Jensen Michael C. , Rader Christoph , Riddell Stanley R.
Published: April 2023

PDF File - 102K, Legend for Supplementary Figures 1-5
Supplementary Table 1 from Inhibition of Histone Deacetylation Potentiates the Evolution of Acquired Temozolomide Resistance Linked to MGMT Upregulation in Glioblastoma Xenografts
Authors: Kitange Gaspar J. , Mladek Ann C. , Carlson Brett L. , Schroeder Mark A. , Pokorny Jenny L. , Cen Ling , Decker Paul A. , Wu Wenting , Lomberk Gwen A. , Gupta Shiv K. , Urrutia Raul A. , Sarkaria Jann N.
Published: April 2023

PDF file - 7K, The summary of the TMZ response: Parental vs TMZ resistant xenografts
Supplementary Figure 3 from Inhibition of Histone Deacetylation Potentiates the Evolution of Acquired Temozolomide Resistance Linked to MGMT Upregulation in Glioblastoma Xenografts
Authors: Kitange Gaspar J. , Mladek Ann C. , Carlson Brett L. , Schroeder Mark A. , Pokorny Jenny L. , Cen Ling , Decker Paul A. , Wu Wenting , Lomberk Gwen A. , Gupta Shiv K. , Urrutia Raul A. , Sarkaria Jann N.
Published: April 2023

PDF file - 133K
Supplementary Figure 5 from CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem–like Cells Stratify Prognostic Risks of Colorectal Cancer
Authors: Deng Yong-Jian , Tang Na , Liu Chao , Zhang Jiang-Yu , An Sheng-Li , Peng Yin-Li , Ma Li-Li , Li Guang-Qiu , Jiang Qiang , Hu Chun-Ting , Wang Ya-Nan , Liang Yao-Ze , Bian Xiu-Wu , Fang Wei-Gang , Ding Yan-Qing
Published: April 2023

PDF file - 2897K, Stemness of cancer stem-like cells related to ERp29, CLIC4 and Smac.
Supplementary Figure 4 from CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem–like Cells Stratify Prognostic Risks of Colorectal Cancer
Authors: Deng Yong-Jian , Tang Na , Liu Chao , Zhang Jiang-Yu , An Sheng-Li , Peng Yin-Li , Ma Li-Li , Li Guang-Qiu , Jiang Qiang , Hu Chun-Ting , Wang Ya-Nan , Liang Yao-Ze , Bian Xiu-Wu , Fang Wei-Gang , Ding Yan-Qing
Published: April 2023

PDF file - 556K, Biological process annotation with Gene Ontology analysis for 27 proteins.
Supplementary Methods, Tables 1-4, Figures 1-14 from TP53 Genomic Status Regulates Sensitivity of Gastric Cancer Cells to the Histone Methylation Inhibitor 3-Deazaneplanocin A (DZNep)
Authors: Cheng Lai Ling , Itahana Yoko , Lei Zheng Deng , Chia Na-Yu , Wu Yonghui , Yu Yingnan , Li Zhang Shen , Thike Aye Aye , Pandey Anuradha , Rozen Steve , Voorhoeve Pieter Mathijs , Yu Qiang , Tan Puay Hoon , Bay Boon Huat , Itahana Koji , Tan Patrick
Published: April 2023

PDF file - 484K, Table S1. Clinical Characteristics of the GC Cohort Analyzed in this Study. Table S2. Differentially-Regulated Genes in DZNep-Sensitive and Resistant Lines after DZNep Treatment. Table S3. Genomic Status of TP53 in Gastric Cancer Cell Lines. Table S4. p53-related Genes Upregulated in DZNep-Sensitive Lines. Figure S1. PRC2 Components mRNA Expression in Primary Gastric Tissues and Cell Lines. Figure S2. DZNep Treatment Does Not Alter Global H3K27 Acetylation Status. Figure S3. Effects of DZNep on SUZ12 and EED Depletion. Figure S4. DZNep Does Not Cause TP53 Transcriptional Upregulation. Figure S5. EZH2 Inhibition Stabilizes and Activates p53. Figure S6. DZNep Effects on DNA Damage Markers. Figure S7. DZNep Treatment Does Not Affect MDM2-p53 Interactions. Figure S8. DZNep Treatment and EZH2 Inhibition Both Induce USP10 Upregulation. Figure S9. USP10 Inhibition Attenuates DZNep-Induced p53 Accumulation in Sensitive Cells. Figure S10. DZNep Treatment Does Not Alter Levels of K372 Mono-methylated p53. Figure S11. p53 and USP10 Expression in Parental and p53 Knockdown Cells after DZNep Treatment. Figure S12. Relationship between p53 Pathway Activity and EZH2 Expression in Primary Breast Cancers. Figure S13. EZH2 and p53 Immunohistochemistry in Primary GCs. Figure S14. Proposed Model for EZH2-Mediated Repression of p53.
Supplementary Figure 1 from CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem–like Cells Stratify Prognostic Risks of Colorectal Cancer
Authors: Deng Yong-Jian , Tang Na , Liu Chao , Zhang Jiang-Yu , An Sheng-Li , Peng Yin-Li , Ma Li-Li , Li Guang-Qiu , Jiang Qiang , Hu Chun-Ting , Wang Ya-Nan , Liang Yao-Ze , Bian Xiu-Wu , Fang Wei-Gang , Ding Yan-Qing
Published: April 2023

PDF file - 5616K, Generation of tumor spheres and determining the metastatic potentials of the tumor spheres from different metastatic single cell progenies (SCP).
Supplementary Table S3 from Radiotherapy of Human Sarcoma Promotes an Intratumoral Immune Effector Signature
Authors: Sharma Anu , Bode Beata , Studer Gabriela , Moch Holger , Okoniewski Michal , Knuth Alexander , von Boehmer Lotta , van den Broek Maries
Published: April 2023

Supplementary Table S3 - PDF file 1084K, IHC quantification of Cancer Testis antigen and MHC-I expression in sarcoma patients before and after radiotherapy
Supplementary Table S1 from Radiotherapy of Human Sarcoma Promotes an Intratumoral Immune Effector Signature
Authors: Sharma Anu , Bode Beata , Studer Gabriela , Moch Holger , Okoniewski Michal , Knuth Alexander , von Boehmer Lotta , van den Broek Maries
Published: April 2023

Supplementary Table S1 - PDF file 558K, Patient information: The table summarizes patient diagnosis, survival status and the time of biopsy collection following radiotherapy. All patients received only neo-adjuvant radiotherapy (RT) and underwent surgery as part of their standard treatment regimen. N: number of patients, MPNST: malignant peripheral nerve sheath tumor, NOS: not otherwise specified
Supplementary Figure 2 from Vemurafenib Synergizes with Nutlin-3 to Deplete Survivin and Suppresses Melanoma Viability and Tumor Growth
Authors: Ji Zhenyu , Kumar Raj , Taylor Michael , Rajadurai Anpuchchelvi , Marzuka-Alcalá Alexander , Chen Y. Erin , Njauw Ching-Ni Jenny , Flaherty Keith , Jönsson Göran , Tsao Hensin
Published: April 2023

PDF file, 88K, Nutlin-3 induces p53 and Hdm2 but not Mdm4 even though the basal levels of Mdm4 is higher than Hdm2.
Legend from Radiotherapy of Human Sarcoma Promotes an Intratumoral Immune Effector Signature
Authors: Sharma Anu , Bode Beata , Studer Gabriela , Moch Holger , Okoniewski Michal , Knuth Alexander , von Boehmer Lotta , van den Broek Maries
Published: April 2023

Legend - PDF file 81K, Legend
Supplementary Table 3 from Molecular Pathways: The Complexity of the Epigenome in Cancer and Recent Clinical Advances
Authors: Conte Mariarosaria , Altucci Lucia
Published: April 2023

PDF file, 78K, Schematic classification of HDAC inhibitors in clinical trials for cancer treatment. The main HDACi used in clinical trials against cancer are indicated.
Data Supplement from Comprehensive Biomarker Analysis and Final Efficacy Results of Sorafenib in the BATTLE Trial
Authors: Blumenschein George R. , Saintigny Pierre , Liu Suyu , Kim Edward S. , Tsao Anne S. , Herbst Roy S. , Alden Christine , Lee J. Jack , Tang Ximing , Stewart David J. , Kies Merrill S. , Fossella Frank V. , Tran Hai T. , Mao L. , Hicks Marshall E. , Erasmus Jeremy , Gupta Sanjay , Girard Luc , Peyton Michael , Diao Lixia , Wang Jing , Davis Suzanne E. , Minna John D. , Wistuba Ignacio , Hong Waun K. , Heymach John V. , Lippman Scott M.
Published: April 2023

Supplementary Material and Methods
Data Supplement from Comprehensive Biomarker Analysis and Final Efficacy Results of Sorafenib in the BATTLE Trial
Authors: Blumenschein George R. , Saintigny Pierre , Liu Suyu , Kim Edward S. , Tsao Anne S. , Herbst Roy S. , Alden Christine , Lee J. Jack , Tang Ximing , Stewart David J. , Kies Merrill S. , Fossella Frank V. , Tran Hai T. , Mao L. , Hicks Marshall E. , Erasmus Jeremy , Gupta Sanjay , Girard Luc , Peyton Michael , Diao Lixia , Wang Jing , Davis Suzanne E. , Minna John D. , Wistuba Ignacio , Hong Waun K. , Heymach John V. , Lippman Scott M.
Published: April 2023

Gene sets associated with resistance.
Supplementary Tables 1-6 from A Randomized Phase II Trial of Multiepitope Vaccination with Melanoma Peptides for Cytotoxic T Cells and Helper T Cells for Patients with Metastatic Melanoma (E1602)
Authors: Slingluff Craig L. , Lee Sandra , Zhao Fengmin , Chianese-Bullock Kimberly A. , Olson Walter C. , Butterfield Lisa H. , Whiteside Theresa L. , Leming Philip D. , Kirkwood John M.
Published: April 2023

Supplementary Table 1: Patient demographics. Supplementary Table 2: T cell response rates by arm. Supplementary Table 3: Peptide-specific immune response by HLA type. Supplementary Table 4: Number of patients in each group defined by sex, visceral disease and ECOG PS. Supplementary Table 5: Predicted 1-year OS rate (using Korn method) and observed 1-year OS rate for E1602 patients. Supplementary Table 6: treatment related toxicity.
Supplementary Methods and Materials and Results from A Randomized Phase II Trial of Multiepitope Vaccination with Melanoma Peptides for Cytotoxic T Cells and Helper T Cells for Patients with Metastatic Melanoma (E1602)
Authors: Slingluff Craig L. , Lee Sandra , Zhao Fengmin , Chianese-Bullock Kimberly A. , Olson Walter C. , Butterfield Lisa H. , Whiteside Theresa L. , Leming Philip D. , Kirkwood John M.
Published: April 2023

PDF - 104K.
Supplementary Figures 1 and 2 from A Randomized Phase II Trial of Multiepitope Vaccination with Melanoma Peptides for Cytotoxic T Cells and Helper T Cells for Patients with Metastatic Melanoma (E1602)
Authors: Slingluff Craig L. , Lee Sandra , Zhao Fengmin , Chianese-Bullock Kimberly A. , Olson Walter C. , Butterfield Lisa H. , Whiteside Theresa L. , Leming Philip D. , Kirkwood John M.
Published: April 2023

PDF - 433K, Supplementary Figure 1: Study Schema. Supplementary Figure 2: Association of overall survival and immune response to 6MHP, detail by study arm (Arm C and Arm D.)
Supplementary Figure Legend from Nanoparticles Engineered with Rituximab and Loaded with Nutlin-3 Show Promising Therapeutic Activity in B-Leukemic Xenografts
Authors: Voltan Rebecca , Secchiero Paola , Ruozi Barbara , Forni Flavio , Agostinis Chiara , Caruso Lorenzo , Vandelli Maria Angela , Zauli Giorgio
Published: April 2023

PDF file - 90K
Related Article from Serum Cholesterol and mTOR Inhibitors: Surrogate Biomarker or Epiphenomenon?
Authors: Cho Daniel C. , Atkins Michael B.
Published: April 2023

Related Article from Serum Cholesterol and mTOR Inhibitors: Surrogate Biomarker or Epiphenomenon?
Supplementary Figure 2 from Nanoparticles Engineered with Rituximab and Loaded with Nutlin-3 Show Promising Therapeutic Activity in B-Leukemic Xenografts
Authors: Voltan Rebecca , Secchiero Paola , Ruozi Barbara , Forni Flavio , Agostinis Chiara , Caruso Lorenzo , Vandelli Maria Angela , Zauli Giorgio
Published: April 2023

PDF file - 121K, Supplementary Figure 2. Comparative in vitro assessment of p53 activation.
Supplementary Table from Acquired Resistance to Anti-VEGF Therapy in Glioblastoma Is Associated with a Mesenchymal Transition
Authors: Piao Yuji , Liang Ji , Holmes Lindsay , Henry Verlene , Sulman Erik , de Groot John F.
Published: April 2023

PDF file, 21K, Genes significantly increased following acquired resistance to bevacizumab.
Supplementary Figure 4 from Aberrant BAF57 Signaling Facilitates Prometastatic Phenotypes
Authors: Balasubramaniam Sucharitha , Comstock Clay E.S. , Ertel Adam , Jeong Kwang Won , Stallcup Michael R. , Addya Sankar , McCue Peter A. , Ostrander William F. , Augello Michael A. , Knudsen Karen E.
Published: April 2023

PDF file - 2249K, BAF57 aberrations govern pro-metastatic phenotypes.
Supplementary Figure 2 from Aberrant BAF57 Signaling Facilitates Prometastatic Phenotypes
Authors: Balasubramaniam Sucharitha , Comstock Clay E.S. , Ertel Adam , Jeong Kwang Won , Stallcup Michael R. , Addya Sankar , McCue Peter A. , Ostrander William F. , Augello Michael A. , Knudsen Karen E.
Published: April 2023

PDF file - 2354K, Microarray analyses of BAF57 deregulation.
Supplementary Figure 1 from Worth Adapting? Revisiting the Usefulness of Outcome-Adaptive Randomization
Authors: Lee J. Jack , Chen Nan , Yin Guosheng
Published: April 2023

PDF file, 68k, Supplementary Figure 1A and 1B: Additional number of non-responders versus number of patients accrued with early stopping.
Supplementary Tables 1 - 3 from Improved Statistical Modeling of Tumor Growth and Treatment Effect in Preclinical Animal Studies with Highly Heterogeneous Responses In Vivo
Authors: Laajala Teemu D. , Corander Jukka , Saarinen Niina M. , Mäkelä Katja , Savolainen Saija , Suominen Mari I. , Alhoniemi Esa , Mäkelä Sari , Poutanen Matti , Aittokallio Tero
Published: April 2023

PDF file, 134K, Model covariates and results from simulation experiment and probabilistic categorization.
Supplementary Figure 1 from Relationship between 18F-Fluorodeoxyglucose Accumulation and KRAS/BRAF Mutations in Colorectal Cancer
Authors: Kawada Kenji , Nakamoto Yuji , Kawada Mayumi , Hida Koya , Matsumoto Takuya , Murakami Teppei , Hasegawa Suguru , Togashi Kaori , Sakai Yoshiharu
Published: April 2023

PDF file - 491K
Supplementary Table 2 from EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival
Authors: Smits Michiel , van Rijn Sjoerd , Hulleman Esther , Biesmans Dennis , van Vuurden Dannis G. , Kool Marcel , Haberler Christine , Aronica Eleonora , Vandertop W. Peter , Noske David P. , Würdinger Thomas
Published: April 2023

PDF file, 67KB, (A) List of down-regulated genes in medulloblastoma versus normal cerebellar precursor cells in at least five out of seven mouse medulloblastoma datasets that are also down-regulated in human medulloblastoma versus normal cerebellum. (B) List of genes with GeneOntology "tumor suppressor" own-regulated in at least three out of seven mouse medulloblastoma datasets that are also down-regulated in human medulloblastoma versus normal cerebellum.
Supplementary Table 1 from EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival
Authors: Smits Michiel , van Rijn Sjoerd , Hulleman Esther , Biesmans Dennis , van Vuurden Dannis G. , Kool Marcel , Haberler Christine , Aronica Eleonora , Vandertop W. Peter , Noske David P. , Würdinger Thomas
Published: April 2023

PDF file, 79KB, (A) Microarray datasets characteristics. (B) List of tumor suppressor genes, established by interrogating the Amigo and NCBI Gene Ontology (GO) databases.
Supplementary Figure 4 from EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival
Authors: Smits Michiel , van Rijn Sjoerd , Hulleman Esther , Biesmans Dennis , van Vuurden Dannis G. , Kool Marcel , Haberler Christine , Aronica Eleonora , Vandertop W. Peter , Noske David P. , Würdinger Thomas
Published: April 2023

PDF file, 27KB, Colony formation of DAB2IP overexpressing Daoy cells following treatment with a low dose of TNFα compared to untreated cells.
Supplementary Table 3 from Tumor Stromal Architecture Can Define the Intrinsic Tumor Response to VEGF-Targeted Therapy
Authors: Smith Neil R. , Baker Dawn , Farren Matthew , Pommier Aurelien , Swann Ruth , Wang Xin , Mistry Sunita , McDaid Karen , Kendrew Jane , Womack Chris , Wedge Stephen R. , Barry Simon T.
Published: April 2023

PDF file - 52K, Clinicopathology data for whole human diagnostic cancer specimens.
Supplementary Figure 1 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy
Authors: Kemp Clinton D. , Rao Mahadev , Xi Sichuan , Inchauste Suzanne , Mani Haresh , Fetsch Patricia , Filie Armando , Zhang Mary , Hong Julie A. , Walker Robert L. , Zhu Yuelin J. , Ripley R. Taylor , Mathur Aarti , Liu Fang , Yang Maocheng , Meltzer Paul A. , Marquez Victor E. , De Rienzo Assunta , Bueno Raphael , Schrump David S.
Published: April 2023

PDF file - 661K, Photomicrographs of NMES1 and NMES2 normal pleura cultures, and MES1 through MES4 mesothelioma cell lines established at the NCI.
Supplementary Figure 1 from Molecular Profiling of Aromatase Inhibitor–Treated Postmenopausal Breast Tumors Identifies Immune-Related Correlates of Resistance
Authors: Dunbier Anita K. , Ghazoui Zara , Anderson Helen , Salter Janine , Nerurkar Ashutosh , Osin Peter , A'hern Roger , Miller William R. , Smith Ian E. , Dowsett Mitch
Published: April 2023

PDF file - 109K, Derivation of samples for microarray analysis.
Supplementary Figure 1 from Tumor-Associated Macrophages in Pediatric Classical Hodgkin Lymphoma: Association with Epstein-Barr Virus, Lymphocyte Subsets, and Prognostic Impact
Authors: Barros Mário Henrique M. , Hassan Rocio , Niedobitek Gerald
Published: April 2023

PDF file, 76KB, Box-plot graph showing the numerical distribution of lymphocyte populations, macrophages and dendritic cells in the tumor microenvironment of pediatric classical Hodgkin lymphoma.
Supplementary Table 1 from Contrasted Outcomes to Gefitinib on Tumoral IGF1R Expression in Head and Neck Cancer Patients Receiving Postoperative Chemoradiation (GORTEC Trial 2004-02)
Authors: Thariat Juliette , Bensadoun René-Jean , Etienne-Grimaldi Marie-Christine , Grall Dominique , Penault-Llorca Frédérique , Dassonville Olivier , Bertucci Francois , Cayre Anne , De Raucourt Dominique , Geoffrois Lionnel , Finetti Pascal , Giraud Philippe , Racadot Séverine , Morinière Sylvain , Sudaka Anne , Van Obberghen-Schilling Ellen , Milano Gérard
Published: April 2023

PDF file, 31K, Description of mean median min and max values for each biomarker.
Supplementary Figures 1-8, Tables 1-3 from Significance of Dysregulated Metadherin and MicroRNA-375 in Head and Neck Cancer
Authors: Hui Angela B.Y. , Bruce Jeff P. , Alajez Nehad M. , Shi Wei , Yue Shijun , Perez-Ordonez Bayardo , Xu Wei , O'Sullivan Brian , Waldron John , Cummings Bernard , Gullane Patrick , Siu Lillian , Liu Fei-Fei
Published: April 2023

PDF file - 274K
Supplementary Table 3 from Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer
Authors: Madhavan Dharanija , Zucknick Manuela , Wallwiener Markus , Cuk Katarina , Modugno Caroline , Scharpff Martina , Schott Sarah , Heil Jörg , Turchinovich Andrey , Yang Rongxi , Benner Axel , Riethdorf Sabine , Trumpp Andreas , Sohn Christof , Pantel Klaus , Schneeweiss Andreas , Burwinkel Barbara
Published: April 2023

XLS file, 11K, Limma analysis of TaqMan array data.
Supplementary Table 2 from The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study
Authors: Winocur Gordon , Henkelman Mark , Wojtowicz J. Martin , Zhang Haibo , Binns Malcolm A. , Tannock Ian F.
Published: April 2023

PDF file, 85KB, Supplementary Table S2. Mean brain volume and proportion of total brain volume (�sd) of several brain structures at three time points over the course of the experiment. There were no significant differences between measurements in the chemotherapy or saline treated group.
Supplementary Table 1 from A Functional Variant at 19q13.3, rs967591G>A, Is Associated with Shorter Survival of Early-Stage Lung Cancer
Authors: Jeon Hyo-Sung , Jin Guang , Kang Hyo-Gyoung , Choi Yi Young , Lee Won Kee , Choi Jin Eun , Bae Eun Young , Yoo Seung Soo , Lee Shin Yup , Lee Eung Bae , Kim Young Tae , Lee Jaehee , Cha Seung-Ick , Kim Chang Ho , Jheon Sanghoon , Kim In San , Park Jae Yong
Published: April 2023

PDF file - 70K, Primers used in this study.
Supplementary Figure Legend from A Functional Variant at 19q13.3, rs967591G>A, Is Associated with Shorter Survival of Early-Stage Lung Cancer
Authors: Jeon Hyo-Sung , Jin Guang , Kang Hyo-Gyoung , Choi Yi Young , Lee Won Kee , Choi Jin Eun , Bae Eun Young , Yoo Seung Soo , Lee Shin Yup , Lee Eung Bae , Kim Young Tae , Lee Jaehee , Cha Seung-Ick , Kim Chang Ho , Jheon Sanghoon , Kim In San , Park Jae Yong
Published: April 2023

PDF file - 56K
Supplementary Figure 5 from The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study
Authors: Winocur Gordon , Henkelman Mark , Wojtowicz J. Martin , Zhang Haibo , Binns Malcolm A. , Tannock Ian F.
Published: April 2023

PDF file, 61KB, Figure S5. Performance of CHEMO and SAL groups on the test trials at all study-test intervals of the DNMTS test administered at baseline. Errors represent each group's daily error/trial score averaged over successive days (Blocks), presented in five blocks of two days. (Error bars denote � SEM).
Supplementary Figure 1 from The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study
Authors: Winocur Gordon , Henkelman Mark , Wojtowicz J. Martin , Zhang Haibo , Binns Malcolm A. , Tannock Ian F.
Published: April 2023

PDF file, 56KB, Figure S1. Schematic representation of experimental procedures. Note that tests refer to the learning and memory tests administered at baseline, post-treatment, and at long-term follow-up.
Supplementary Table 6B from AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
Authors: Yap Timothy A. , Walton Mike I. , Grimshaw Kyla M. , te Poele Robert H. , Eve Paul D. , Valenti Melanie R. , de Haven Brandon Alexis K. , Martins Vanessa , Zetterlund Anna , Heaton Simon P. , Heinzmann Kathrin , Jones Paul S. , Feltell Ruth E. , Reule Matthias , Woodhead Steven J. , Davies Thomas G. , Lyons John F. , Raynaud Florence I. , Eccles Suzanne A. , Workman Paul , Thompson Neil T. , Garrett Michelle D.
Published: April 2023

XLS file - 62K, Gene Ontology (GO) analysis for genes significantly altered in expression by CCT128930 ranked according to the P-value of a modified Fisher's exact test (EASE score, DAVID) for enriched Gene Ontology terms
Supplementary Table 5A from AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
Authors: Yap Timothy A. , Walton Mike I. , Grimshaw Kyla M. , te Poele Robert H. , Eve Paul D. , Valenti Melanie R. , de Haven Brandon Alexis K. , Martins Vanessa , Zetterlund Anna , Heaton Simon P. , Heinzmann Kathrin , Jones Paul S. , Feltell Ruth E. , Reule Matthias , Woodhead Steven J. , Davies Thomas G. , Lyons John F. , Raynaud Florence I. , Eccles Suzanne A. , Workman Paul , Thompson Neil T. , Garrett Michelle D.
Published: April 2023

XLS file - 464K, Gene expression data for AT13148: Genes that showed at least a 1.5 Fold Change in at least one treated sample compared to vehicle control and were differentially expressed between the treatment groups (Welch ANOVA FDR5%)
Supplementary Figure Legend from Large-scale Analysis of PDGFRA Mutations in Melanomas and Evaluation of Their Sensitivity to Tyrosine Kinase Inhibitors Imatinib and Crenolanib
Authors: Dai Jie , Kong Yan , Si Lu , Chi Zhihong , Cui Chuanliang , Sheng Xinan , Mao Lili , Li Siming , Lian Bin , Yang Ruifeng , Liu Shujing , Xu Xiaowei , Guo Jun
Published: April 2023

PDF file - 60K
Supplementary Figure 1 from Loss of NAPRT1 Expression by Tumor-Specific Promoter Methylation Provides a Novel Predictive Biomarker for NAMPT Inhibitors
Authors: Shames David S. , Elkins Kristi , Walter Kimberly , Holcomb Thomas , Du Pan , Mohl Dane , Xiao Yang , Pham Thinh , Haverty Peter M. , Liederer Bianca , Liang Xiaorong , Yauch Robert L. , O'Brien Thomas , Bourgon Richard , Koeppen Hartmut , Belmont Lisa D.
Published: April 2023

PDF file 122K, A) Chemical structure of GNE-617, B) cellular NAD and ATP levels in H522 cells after exposure to 4nM GNE-617, C) correlation of NAPRT1 mRNA and protein (n=32, spearman r= 0.88, p,0.0001)
Supplementary Figure 3 from Large-scale Analysis of PDGFRA Mutations in Melanomas and Evaluation of Their Sensitivity to Tyrosine Kinase Inhibitors Imatinib and Crenolanib
Authors: Dai Jie , Kong Yan , Si Lu , Chi Zhihong , Cui Chuanliang , Sheng Xinan , Mao Lili , Li Siming , Lian Bin , Yang Ruifeng , Liu Shujing , Xu Xiaowei , Guo Jun
Published: April 2023

PDF file - 2243K, Figure S3. Genetic mutations in exon 18 of PDGFRA.
Supplementary Figure 2 from Large-scale Analysis of PDGFRA Mutations in Melanomas and Evaluation of Their Sensitivity to Tyrosine Kinase Inhibitors Imatinib and Crenolanib
Authors: Dai Jie , Kong Yan , Si Lu , Chi Zhihong , Cui Chuanliang , Sheng Xinan , Mao Lili , Li Siming , Lian Bin , Yang Ruifeng , Liu Shujing , Xu Xiaowei , Guo Jun
Published: April 2023

PDF file - 1452K, Figure S2. Genetic mutations in exon 14 of PDGFRA.
Supplementary Methods from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Authors: Zhong Cuiling , Wang Jianyong , Li Bing , Xiang Hong , Ultsch Mark , Coons Mary , Wong Terence , Chiang Nancy Y. , Clark Suzy , Clark Robyn , Quintana Leah , Gribling Peter , Suto Eric , Barck Kai , Corpuz Racquel , Yao Jenny , Takkar Rashi , Lee Wyne P. , Damico-Beyer Lisa A. , Carano Richard D. , Adams Camellia , Kelley Robert F. , Wang Weiru , Ferrara Napoleone
Published: April 2023

PDF file, 138K
Supplementary Figure Legends from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Authors: Zhong Cuiling , Wang Jianyong , Li Bing , Xiang Hong , Ultsch Mark , Coons Mary , Wong Terence , Chiang Nancy Y. , Clark Suzy , Clark Robyn , Quintana Leah , Gribling Peter , Suto Eric , Barck Kai , Corpuz Racquel , Yao Jenny , Takkar Rashi , Lee Wyne P. , Damico-Beyer Lisa A. , Carano Richard D. , Adams Camellia , Kelley Robert F. , Wang Weiru , Ferrara Napoleone
Published: April 2023

PDF file, 78K
Supplementary Figure 3 from Increased miR-708 Expression in NSCLC and Its Association with Poor Survival in Lung Adenocarcinoma from Never Smokers
Authors: Jang Jin Sung , Jeon Hyo-Sung , Sun Zhifu , Aubry Marie Christine , Tang Hui , Park Cheol-Hong , Rakhshan Fariborz , Schultz Debra A. , Kolbert Christopher P. , Lupu Ruth , Park Jae Yong , Harris Curtis C. , Yang Ping , Jen Jin
Published: April 2023

PDF file, 154KB, TMEM88 is a putative target of miR-708 by MicroCosm database. The target site of miR-708 is located in the 3'UTR, 286 to 309 bases from downstream of the stop codon sequence of TMEM88. Asterisks indicate the binding site.
Supplementary Figure 2 from Increased miR-708 Expression in NSCLC and Its Association with Poor Survival in Lung Adenocarcinoma from Never Smokers
Authors: Jang Jin Sung , Jeon Hyo-Sung , Sun Zhifu , Aubry Marie Christine , Tang Hui , Park Cheol-Hong , Rakhshan Fariborz , Schultz Debra A. , Kolbert Christopher P. , Lupu Ruth , Park Jae Yong , Harris Curtis C. , Yang Ping , Jen Jin
Published: April 2023

PDF file, 90KB, Endogenous expression level of miR-708 in various cell lines. Real-time quantitative polymerase chain reaction analyses were performed as described in the "Methods" section.
Supplementary Figure 6 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 2068K, Correlation of SphK1 expression with clinical data in colorectal cancer patients
Supplementary Figure Legend from Predictive Biomarkers of Sensitivity to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Breast Cancer Models
Authors: Diamond Jennifer R. , Eckhardt S. Gail , Tan Aik Choon , Newton Timothy P. , Selby Heather M. , Brunkow Kelsey L. , Kachaeva Maria I. , Varella-Garcia Marileila , Pitts Todd M. , Bray Mark R. , Fletcher Graham C. , Tentler John J.
Published: April 2023

PDF file - 89K
Supplementary Figure 2 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 483K, Effects of SphK1 inhibition by DMS on cetuximab sensitivity in resistant colorectal cancer cell lines
Supplementary Figure 1 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 357K, Sensitivity to cetuximab of a panel of human colorectal cancer cell lines
Supplementary Fig 2 from Weekly nab-Rapamycin in Patients with Advanced Nonhematologic Malignancies: Final Results of a Phase I Trial
Authors: Gonzalez-Angulo Ana M. , Meric-Bernstam Funda , Chawla Sant , Falchook Gerald , Hong David , Akcakanat Argun , Chen Huiqin , Naing Aung , Fu Siqing , Wheler Jennifer , Moulder Stacy , Helgason Thorunn , Li Shaoyi , Elias Ileana , Desai Neil , Kurzrock Razelle
Published: April 2023

A) Association of PBMC 4EBP1 T70 levels with serum rapamycin concentrations; B) Association of PBMC S6K T389 levels with serum rapamycin concentrations
Supplementary Figures 1 and 2 from Src Inhibition with Saracatinib Reverses Fulvestrant Resistance in ER-Positive Ovarian Cancer Models In Vitro and In Vivo
Authors: Simpkins Fiona , Hevia-Paez Pedro , Sun Jun , Ullmer Wendy , Gilbert Candace A. , da Silva Thiago , Pedram Ali , Levin Ellis R. , Reis Isildinha M. , Rabinovich Brian , Azzam Diana , Xu Xiang-Xi , Ince Tan A. , Yang Ji-Yeon , Verhaak Roel G.W. , Lu Yiling , Mills Gordon B. , Slingerland Joyce M.
Published: April 2023

PDF file, 86K, S1: Estrogen alone stimulates cell cyle re-entry of starved PEO1R; S2: Xenografted animal weights were not affected by drug.
Supplementary Figures 1 - 3 from Interleukin 15 Provides Relief to CTLs from Regulatory T Cell–Mediated Inhibition: Implications for Adoptive T Cell–Based Therapies for Lymphoma
Authors: Perna Serena K. , De Angelis Biagio , Pagliara Daria , Hasan Sayyeda T. , Zhang Lan , Mahendravada Aruna , Heslop Helen E. , Brenner Malcolm K. , Rooney Cliona M. , Dotti Gianpietro , Savoldo Barbara
Published: April 2023

PDF file - 117K, Suppl. Fig. 1. Immunophenotypic characterization of CD4+CD25bright cells and other T-cell subsets isolated from peripheral blood of healthy donors. Suppl. Fig. 2. Titration of the inhibitory function of Tregs and selection of Tregs by flow cell sorting. Suppl. Fig. 3. Comparison of different doses of IL-2 and IL-15 and role of the IL-15Rα.
Supplementary Figure Legend from Interleukin 15 Provides Relief to CTLs from Regulatory T Cell–Mediated Inhibition: Implications for Adoptive T Cell–Based Therapies for Lymphoma
Authors: Perna Serena K. , De Angelis Biagio , Pagliara Daria , Hasan Sayyeda T. , Zhang Lan , Mahendravada Aruna , Heslop Helen E. , Brenner Malcolm K. , Rooney Cliona M. , Dotti Gianpietro , Savoldo Barbara
Published: April 2023

PDF file - 67K