bluuebunny/crossref_metadata_2025 huggingface dataset:
Gaceta de Roma (Valencia, Felipe Mey, 1618-1620). Estudio y edición crítica del primer periódico español
Authors: Soto Escobar Rafael , Díaz Noci Javier , Espejo-Cala Carmen
Published: February 2025

Contiene una una edición crítica de lo que denominamos la Gazeta de Roma, una serie de impresos semiperiódicos que durante al menos dos años (entre 1618 y 1620) publicó en Valencia el taller del impresor Felipe Mey, y que puede ser considerada como el primer periódico de la Península Ibérica. Presentamos los once números hasta ahora recuperados de esta serie, con diferentes títulos pero claramente todos ellos fruto de la misma estrategia editorial. Esperamos que esta edición ponga al alcance de los investigadores estos impresos, cuya consideración debería servir para reescribir en cierta medida el relato de la aparición del periodismo en Europa –pues no parece que pueda sostenerse el lugar común de que esta actividad cultural llega a la península con notable retraso con respecto a las prácticas del centro y norte del continente–. Planteamos por otro lado una metodología y criterios de edición y análisis de los textos informativos de la Edad Moderna, con aplicación de técnicas como el análisis de fuentes, el análisis estilístico y narratológico y al análisis de redes sociales. Con esta edición pretendemos  contribuir al estudio de la historia de los orígenes de los periódicos y del periodismo en España.

Los autores son doctores e investigadores, reputados especialistas en Ciencias de la Comunicación. Rafael Soto Escobar es Técnico Auxiliar Especialista en Archivos y Bibliotecas, tarea que compagina con la investigación sobre los orígenes del periodismo en España; Javier Díaz Noci es catedrático de la comunicación en la Universidad Pompeu Fabra de Barcelona, y Carmen Espejo Cala es profesora en la Facultad de Comunicación de la Universidad de Sevilla y dirige el proyecto I+D+i “Historia Crítica del Periodismo Andaluz”.
The Structure of Concomitant Pathology in Patients With Hypertrophic Cardiomyopathy in The Older Age Group. Review and Clinical Observations
Authors: Shakaryants G. A. , Belenkov Yu. N. , Kaplunova V. Yu. , Tashina E. I. , Tyurina D. A. , Khabarova N. V. , Vysokykh A. V. , Kasaeva J. M. , Chkotua L. V. , Privalova E. V.
Published: February 2025

Advances in modern drug and surgical treatment of patients with hypertrophic cardiomyopathy (HCM) have resulted in a significant increase in the life expectancy of these extremely severe patients. Therefore, in addition to the genetic markers, major neurohumoral systems and morpho-functional parameters of intracardiac hemodynamics, the course and prognosis of the disease are influenced by concomitant pathology. In infancy and early childhood, HCM is associated with tumors of chromaffin tissue of various localizations; however, the older the patient, the greater the likelihood of developing metabolic syndrome, secondary atherosclerosis and ischemic heart disease (IHD), and hypertension, which significantly complicates the verification of the HCM diagnosis. We have previously described cases of IHD secondary to HCM, which significantly affected the course and prognosis of both diseases. However, in old age, other comorbidities may also occur in addition to the diseases described above. Based on long-term observation of a large cohort of patients, this article analyzes a wide range of HCM combinations with pathology of other organs and systems, including malignant neoplasms, which makes significant adjustments to the treatment of both the underlying disease and cancer. The material is presented in the form of a brief review of literature on this topic and our own clinical observations and studies.
Ammonium and nitrate ratios in the cultivation of tobacco plants
Authors: Souza de Almeida Victor Gabriel , Santos de Souza Girlene , Santos Brito Gildeon , De Jesus Neto Alfredo Teles , Martins de Souza Cristian , Ranulfo dos Santos Anacleto
Published: February 2025

Tobacco (Nicotiana tabacum L.) is a plant of the Solanaceae family and native to the Americas. Brazil is one of the largest tobacco producers and exporters worldwide, and this crop guarantees the income of many small rural producers. Tobacco is very demanding of nitrogen, and adequate levels of this nutrient guarantee longevity of the production chain, maximizing productivity and ensuring quality. Therefore, this study aimed to analyze the effect of ammoniacal (NH4+) and nitric (NO3-) nitrogen in the growth and development of tobacco. A randomized design was applied, using five ammonium and nitrate ratios (NH4+:NO3-): 100:0; 75:25; 50:50; 25:75 and 0:100, with five replications. After 60 days of weekly application of the solution, physiological and growth parameters were assessed: chlorophyll contents a and b; number of leaves; plant height; stem diameter; root, stem, leaf, shoot and total dry mass. The 25:75 ratio (NH4+:NO3-) resulted in an increase of height, number of leaves, stem diameter and leaf dry mass, the latter being the variable of greatest commercial relevance for tobacco cultivation. The highest chlorophyll contents were found under the 100:00 ratio (NH4+:NO3-) supplementation; however, this treatment had the lowest expressions in all other variables and is not recommended for tobacco cultivation.
Productivity and commercial classification of pitaya in orchard with pollination
Authors: Cíntia Gonçalves Sena  , Deilson de Almeida Alves  , Maria do Céu Monteiro Cruz  , Núbia Cassiana Santos  , João Esdras Lima  , Amanda Gonçalves Guimarães
Published: February 2025

Information related to the productivity and classification of pitaya allows the assessment of the need and planning of orchard pollination. The objective of this study was to evaluate the productivity and commercial classification of the pitaya Selenicereus monacanthus with manual cross-pollination management with the species Selenicereus undatus and natural pollination. The evaluations were carried out on a total of 20 plants from an orchard in Minas Gerais, Brazil. Pollen grains were collected from flowers of the S. undatus species plants for cross-pollination with the species S. monacanthus. In the plants corresponding to natural pollination, the flowers were pollinated by natural pollinators. The comparison of manual and natural cross-pollination was performed based on the calculation of the orchard productivity. The commercial classification was performed based on the determination of the individual mass of each fruit. With manual cross-pollination, the estimated productivity of S. monacanthus was 49.2 Mg ha-1, while with natural pollination, it reached 14.3 Mg ha-1, with manual cross-pollination management increasing productivity by 244%. Pitaya with manual cross-pollination receive a better classification and, with natural pollination, most pitaya did not reach the minimum size for commercialization. The commercial classification of pitaya was greater than 50% in the Extra class with manual cross-pollination. With natural pollination, less than 40% of pitaya reached the standard for commercialization.
Trend of Mortality and Disability-Adjusted Life Years (DALYs) Rates Attributed to Occupational Carcinogens in Hamadan Province from 1990 to 2021
Authors: Fattahi-Darghlou Marzieh , Gheibipour Hamid , Mahdavi Neda , Shahbazi Fatemeh
Published: February 2025

Background and Objectives: More than 12 types of cancer are caused by contact with environmental factors and occupational carcinogens. Therefore, this study aimed to evaluate the trend of mortality and disability-adjusted life years (DALYs) rates attributed to occupational carcinogens in Hamedan province, Iran, from 1990 to 2021.
Methods: In this ecological study, the Global Burden of Diseases database was used to collect the required data. The trend of changes in the mortality and disability-adjusted life years rates was examined using joinpoint regression analysis and the Join Point Regression software.
Results: The years of life lost (YLLs) due to premature death and disability attributed to occupational carcinogens in Hamadan Province increased from 10.31 per 1,000 population in 1990 to 23.33 per 1,000 population in 2021. The average annual percent change (AAPC) in DALYs was 3.79% for women and 2.57% for men. The all-cause mortality rate attributed to occupational carcinogens rose from 0.31 per 100,000 population in 1990 to 0.74 per 100,000 in 2021 (AAPC = 2.78%; 95% CI: 2.68% to 2.90%).
Conclusion: The trend of mortality and disability-adjusted life years due to occupational carcinogens in Hamadan province had an increasing trend overally. Periodic screenings for workers in high-risk occupations are essential to mitigate the burden of occupational cancers.
Breeding and training horses for military purposes in the interwar period and their use in the tasks of the home army
Authors: Polaczek-Bigaj Marta
Published: February 2025

Purpose of the study: This study presents the role of Polish cavalry from the perspective of activities that preceded the direct use of horses in combat. The author aims to illustrate the entire process, from horse breeding and recruitment for the army to the training of horses and riders, which ensured the highest level of military and sports proficiency.
Methodology: The study employs an analysis of historical literature, including documents that describe the methods of horse selection and training and the organization of Polish cavalry. The author’s approach encompasses examining the evolution in horse breeding and training practices resulting from the changing tasks assigned to mounted formations.
Main findings: The author demonstrates that Polish cavalry reached a high level of training, which enabled it to gain worldwide recognition and establish a unique Polish school of horseback riding. In the period preceding World War II, there was a shift in Polish military doctrine regarding the role of cavalry in combat, yet during the September Campaign, Polish cavalry proved effective and showed dedication to defending the homeland.
Application of the study: This study may contribute to a better understanding of the importance of cavalry preparation and training, potentially inspiring contemporary military units in training and specialization practices.
Originality/Novelty of the study: The study is unique in its approach, highlighting the role of horses in warfare comprehensively—from breeding to specialized military skills. By analyzing Polish cavalry as a structure rooted in solid training foundations, the author provides new insights into its achievements and contributions to the development of Polish military doctrine.
A PARTICIPAÇÃO FAVORECE A IMPLANTAÇÃO DE UM SISTEMA INTEGRADO DE PRODUÇÃO DE ALIMENTOS, NA ETNIA XERENTE, AMAZÔNIA LEGAL, BRASIL.
Authors: Prysthon Adriano , Mataveli Marcela , Ummus Marta Eichemberger , Munoz Andrea Elena Pizarro
Published: February 2025

Visando construir um modelo integrado de produção de alimentos, realizou-se um mapeamento participativo com a brigada de incêndio da etnia Xerente, região central do Tocantins. O mapeamento revelou a rotina, os hábitos alimentares, as práticas extrativistas e agrícolas, assim como a possibilidade de novas cultivares em um sistema integrado de produção chamado “Sistemão”. Utilizaram-se técnicas como: Matriz de avaliação, Relógio de rotina, Diagrama de Venn, entrevistas e uma Devolutiva. A dinâmica ajudou os Xerentes a priorizar o cultivo de peixes, bananas e hortas como alternativa para a produção de alimentos, preservando o conhecimento tradicional e os hábitos alimentares. O período de dezembro a maio foi o mais recomendado para a implantação do “Sistemão”. A participação gerou uma maior integração entre a equipe técnica e o público-alvo, favorecendo um clima de confiança e contribuindo para o fortalecimento da governança e busca coletiva de melhores políticas públicas voltadas às etnias indígenas no Tocantins e na Amazônia Legal.
Resumos de Dissertações & Teses
Authors: Guedes Lílian Lopes , De Sousa Maura Cardoso , Furtado Mairon De Sousa , Do Carmo Ellen Patrícia Marques , De Andrade Raul Teixeira , Santos Renata De Andrade , De Souza Andrey Mendonça , Ribeiro Laiane Bezerra , Da Fonseca Luiz Carlos Neves
Published: February 2025

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Ratzinger, marxismo y liberación
Authors: Eslava Euclides
Published: February 2025

El marxismo sigue influyendo en los debates filosóficos, políticos y teológicos contemporáneos. En la teología reciente marcó una nueva época con su influencia en las “teologías de la liberación”. Joseph Ratzinger lo estudió desde su juventud y dirigió los trabajos que señalaron la nueva actitud del Magisterio frente a la teología latinoamericana. En este artículo se rastrea su pensamiento sobre el marxismo para señalar las principales conclusiones en cada etapa de su evolución, e inferir las consecuencias prácticas para la sociedad y la Iglesia. Como objetivo secundario se estudia su interpretación del itinerario intelectual de Occidente en el siglo XX.
The relationship between visfatin, resistin and CRP parameters and insulin resistance in obese and non-obese type 2 diabetic individuals
Authors: Yüksel Arzu , Telci Ayşe Gül Sündüs , Kubat Üzüm Ayşe
Published: February 2025

Objectives: Inflammation caused by adipokines such as adiponectin, leptin, resistin, visfatin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) released by fat cells and immune cells within fat tissue is a significant factor in the onset of insulin resistance and Type 2 diabetes mellitus (T2DM). This study explores the relationship among these adipokines and insulin resistance in T2DM patients, focusing on the impact of abdominal obesity.
Methods: The study involved 73 adult T2DM patients who were seperated into two groups based on their body mass index (BMI): 47 were classified as obese (BMI ≥30 kg/m²), and 26 were classified as non-obese (BMI <25 kg/m²). Additionally, 42 healthy controls were included, comprising 18 obese and 24 non-obese individuals. Adipokine concentrations (resistin, leptin, adiponectin, visfatin, IL-6 and TNF-α) were measured with the ELISA method.
Results: The concentrations of adiponectin were substantially lower in T2DM patients relative to the control group (P<0.0125). Leptin concentrations did not show significant differences between the groups, but there was a notable increase in obese controls compared to non-obese controls (P<0.0125). TNF-α concentrations were significantly higher in obese controls than in non-obese controls (P<0.001). Resistin concentrations were significantly correlated with C-reactive protein (CRP) and IL-6 in both groups, independent of BMI (P=0.001 and P<0.0125, respectively). We found that CRP levels were significantly higher in both obese diabetics compared to non-obese diabetics and in obese controls compared to non-obese controls (P<0.0001).
Conclusions: Adipose tissue is a crucial determinant of circulating inflammation markers. Elevated CRP concentrations in obesity may result from insulin resistance rather than being a cause. Further research is required to comprehend the connection between fatty tissue, insulin resistance, and elevated inflammatory markers.
Effect of Integrated Nutrient Management and Plant Growth Regulators on Growth Attributes of Fig (Ficus carica L.) under Semi-Arid Conditions in Rajasthan
Authors:   Department of Horticulture, S. K. N. Agriculture University, Jobner, Jaipur, Jangid Tulsi Ram
Published: February 2025

The present investigation entitled “Effect of integrated nutrient management and plant growth regulators on growth attributes of fig (Ficus carica L.) under semi-arid conditions in Rajasthan was conducted on five-year old fig plants grown in sandy loam soils. While studies on fig are limited, this experiment was conducted to assess the response of the fig cultivar 'Black Ischia' to various organic and inorganic nutrient sources, as well as plant growth regulators, through thirty-two treatments replicated three times. During the investigation, the result revealed that the fig plant was studied for the growth parameters viz., shoot length, shoot girth, number of fruiting branches, spread of plant, leaf area and total chlorophyll content was recorded significantly maximum under treatment 50 % RDF + 50 % VC which was over rest of the treatments. However, the treatment 50 % RDF + 50 % PM and 50 % RDF + 50 % FYM was found statistically at par with it. Similarly, the shoot length, shoot girth, number of fruiting branches per plant, the spread of the plant, leaf area and total chlorophyll content were recorded significantly maximum under treatment 50 % GA3 + 50 % NAA over the rest of the treatments, including control.
Chickpeas vs. Mung Beans: Unlocking the Nutritional Potential of Seeds and Sprouts
Authors:   Department of Biotechnology, Techno India University, EM4 building, Bidhannagar, Kolkata 700091, Bhattacharya Malavika
Published: February 2025

It is important to remember that a wide variety of food supplements are available today in the form of tablets and capsules to help combat various diseases and support overall health. Nutrient-rich legumes, in particular, have been demonstrated to provide numerous health advantages and indirectly facilitate a healthy immune response. However, individual dietary choices and overall dietary patterns are crucial to maintaining a healthy lifestyle and preventing illness. Eating a healthy and balanced diet is important to improve your immune system.
In a recent study, two varieties of pulses, namely Vigna radiata (mung bean) and Cicer arietinum (chickpea), were analyzed in two distinct forms, namely crushed and soaked. The research centred on their nutritional composition, in vitro antimicrobial activity, and antioxidant properties, utilizing established protocols. The results revealed that the crushed form of Cicer arietinum contained the highest concentrations of Vitamin B1, Vitamin C, and carbohydrates, and demonstrated the strongest antibacterial activity among the four samples. In the interim, crushed Vigna radiata exhibited the most potent antioxidant properties, whereas soaked Vigna radiata displayed the highest protein content. These findings suggest that healthcare professionals should consider recommending these nutrient-rich legumes as a component of a balanced diet to enhance immune health.
Chickpeas possess a diverse array of phytocompounds, including proteins, carbohydrates, alkaloids, and flavonoids.Vigna radiata (mung bean) is renowned for its high protein content and potent antioxidant properties, with its extracts also demonstrating anti-angiogenic effects.
This study aims to evaluate the nutritional composition, antimicrobial activity, and antioxidant properties of Vigna radiata and Cicer arietinum in their crushed and soaked forms, providing insights for healthcare professionals to recommend these legumes for improved immune health.
Comparative Studies of Physico-chemical Characteristics of Different Cultivars of Aonla (Emblica officinalis Gaerth.) Under Sub-tropical Condition
Authors:   Bhai Gurdas Degree College, Sangrur, Punjab-India, Singh Krishan Kumar
Published: February 2025

An investigation was conducted in anola crop during 2022-2023 to find out variation in fruit and fruit characteristics of different Aonla (Emblica officinalis Gaerth.) cultivars. NA-6, NA-7, NA-10, Kanchan and Chakaiya were taken up under semi-arid condition of Bhai Gurdas Degree College, Sangrur, Punjab-India. The experimental findings pertaining to fruit physical yield attribute characters such as number of fruits, weight of fruit, stone and seed, length of fruit, diameter of fruit, and chemical characters such as moisture percentage, TSS, total sugar and vitamin-C content in aonla cultivars. The number of fruits per kg of aonla fruits (273) was found significantly maximum under wild cultivar, followed by NA-10 (61) and it was statistically non -significant to Chakaiya cultivar with 58.75 fruits/kg and the minimum number of fruits per kg (50.75) was recorded in NA-7 cultivar. The maximum fruit weight (22.25 g) was recorded in under Banarasi but it was statistically at par with NA-7 and Chakaiya cultivars 21.88 and 21.43 (g).
Material composition of coal mining waste from the Prokopyevskugol Processing Plant and the prospect of using the screw separation method for their enrichment
Authors: Tureckaya N. , Chikisheva T. , Komarova A.
Published: February 2025

The article contains information about the material composition of coal sludge of the Prokopievskugol Processing Plant. The material is 75.54 % represented by polyphase aggregates of coal, clay minerals, quartz and carbonates with different quantitative ratios of components. The ash content of the feedstock is 32.5 %. The productive size range for this raw material has been determined — from 0.04 to 1 mm. We found that the raw materials were of practical interest in obtaining coal concentrate by screw separation. Our technological tests resulted in coal concentrate with an ash content of 10.95 % of dry fuel from coal sludge by screw separation.
Multi-modal Stacked Ensemble Model for Breast Cancer Prognosis Prediction
Authors: Maigari Aminu , Zainol Zurinahni , Xinying Chew
Published: February 2025

Breast cancer (BC) is a global health challenge that affects millions of women worldwide and leads to significant mortality. Recent advancements in next-generation sequencing technology have enabled comprehensive diagnosis and prognosis determination using multiple data modalities. Deep learning methods have shown promise in utilizing these multimodal data sources, outperforming single-modal models. However, integrating these heterogeneous data sources poses significant challenges in clinical decision-making. This study proposes an optimized multimodal CNN for a stacked ensemble model (OMCNNSE) for breast cancer prognosis. Our novel method involves the integration of the Tug of War (TWO) algorithm to optimize the hyperparameters of a convolutional neural network (CNN), enhancing feature extraction from three distinct multimodal datasets: clinical profile data, copy number alteration (CNA), and gene expression data. Specifically, we employ the TWO algorithm to optimize separate CNN models for each dataset, identifying optimal values for the hyperparameters. We then trained the three baseline CNN models using the optimized values through 10-fold crossvalidation. Finally, we utilize an ensemble learning approach to integrate the models’ predictions and apply an SVM classifier for the final prediction. To evaluate the proposed method, we conducted experiments on the METABRIC breast cancer dataset comprising diverse patient profiles. Our results demonstrated the effectiveness of the OMCNNSE approach for predicting breast cancer prognosis. The model achieved high AUC, accuracy, sensitivity, precision, and MCC, outperforming traditional single-modal models and other state-of-the-art methods.
Ações Afirmativas e estudos africanos
Authors: Malaquias Greg Alexandre , Tomaz Maria Helena
Published: February 2025

Este trabalho refere-se à ação extensionista de cunho cultural, ações afirmativas e suas interseccionalidades desenvolvida pelo Neabi/Faculdade Municipal de Palhoça, Laborei/Universidade do Estado de Santa Catarina e GEMPA/Grupo de Estudos Gênero e Empoderamento da Mulher de Palhoça, decorrente do I, II e III Ciclos de Estudos Feministas Miriam Maria Maria, voltados à comunidade acadêmica e geral, com o objetivo de compartilhar estudos acerca dos feminismos negros e decoloniais realizados. A partir do Edital Campus da Cultura Udesc 2021-2022 lançado pela Pró-Reitoria de Extensão, Cultura e Comunidade (Proex), o documentário audiovisual é produzido em forma de curta-metragem sobre as experiências de quatro mulheres da região da grande Florianópolis que atuam ativamente em suas comunidades nas áreas da cultura, religiosidade e política pública. Denominado “Matripotência: a revolução do cuidado na ilha da magia”, o curta destaca à dimensão do cuidado presente nessas práticas, cuja compreensão e reflexão foi percorrida à luz da cosmovisão iorubá de matripotência, desenvolvida pela socióloga nigeriana Oyèronké Oyewùmí a partir da publicação de sua obra ”A invenção das mulheres: construindo um sentido africano para os discursos ocidentais de gênero”. O resultado dos estudos e a produção do audiovisual possibilita uma poética da resistência a partir do aprofundamento do conhecimento sobre as dinâmicas de gênero nas sociedades africanas e decolonialidade, buscando apontar algumas reflexões acerca de outras configurações de corpo, gênero e visões de mundo.
A educação política e o tripé universitário
Authors: Pereira Eduardo José Rezende , Lima Luiz Gabriel Natividade , Boró Simone
Published: February 2025

As diversas iniciativas de educação política se fazem mais do que necessárias para a reversão do atual cenário de desinformação, da falta de engajamento e do descrédito com a política que atinge a sociedade brasileira, em geral, e, em particular, a juventude. Este artigo tem por objetivo apresentar o Programa de Extensão em Educação Política (PROEEP), vinculado ao Instituto de Filosofia e Ciências Humanas (IFCH), da Universidade Estadual de Campinas (Unicamp), que, a partir de atividades presenciais e virtuais, por meio de ações formativas e lúdicas, e tendo como foco a juventude brasileira, promove educação política e estabelece vínculos entre a universidade e a sociedade. No artigo, são apresentadas as diferentes ferramentas de educação política promovidas pelo PROEEP, divididas entre ações extensionistas, práticas de ensino e realização de pesquisa científica. Além de qualificar a estrutura interna do programa, que pode ser apropriada por outras iniciativas extensionistas, o artigo apresenta os materiais paradidáticos desenvolvidos pelo PROEEP para promover informações sobre a política institucional, bem como as ações formativas internas e externas à universidade, que não apenas democratizam o conhecimento acadêmico sobre a política como fortalecem o senso de engajamento cidadão.
Analyzing the Impact of Financial and Macroeconomic Factors on Stock Returns and Firm Value in The Indonesia’s Consumer Cyclicals Sector
Authors: Hidayat Fahranik Maulia , Rikumahu Brady
Published: February 2025

Stock returns reflect the investment returns investors receive from owning company shares, encompassing both dividends and stock price increases. High stock returns indicate strong company performance and are attractive to investors, often reflecting market expectations of the company's future profitability and contributing to increased company value. Conversely, low stock returns can reduce market confidence and negatively impact company value. This study examines factors influencing stock returns in cyclical consumer sector companies listed on the Indonesia Stock Exchange from 2019 to 2023, with a sample of 63 companies out of 124. The research utilizes principal component analysis (PCA) with regression mediation, analyzing variables such as liquidity, solvency, activity, profitability ratios, financial performance, good corporate governance, and macroeconomic factors. SPSS 25 is used for data analysis. Key findings reveal that Market Value Added (MVA) significantly impacts both stock returns and firm value, while exchange rates and GDP do not significantly affect stock returns or firm value in this sector. The money supply (M2) significantly influences stock returns but not firm value. The Sobel mediation test shows that stock returns significantly mediate the relationship between MVA and M2 with firm value, whereas they do not mediate the effects of exchange rates and GDP on firm value. These results offer insights into the economic and financial factors impacting stock performance and firm value in Indonesia's cyclical consumer sector.
Test Results for a Novel 20 kW Two-Phase Pumped Cooling System for Aerospace Applications
Authors: van Gerner Henk Jan , Luten Tim , Scholten Sigurd , Mühlthaler Georg , Buntz Marcus-Benedict
Published: February 2025

In the EU funded BRAVA project, technologies for a Fuel Cell based Power Generation System for aviation are being developed. In this paper, the test results for a demonstrator for a novel two-phase pumped cooling system with 20 kW cooling capacity are presented. This system uses the evaporation of a liquid to remove waste heat from the heat sources. Several concepts have been tested with this demonstrator, including the ‘no accumulator’ concept, which offers a large mass reduction compared to conventional cooling systems. Also, the system can be rotated, and the influence of the orientation has been tested.
The Management of Adrenocortical Carcinomas in The Era of Precision Medicine
Authors: Flauto Fabiano , Ferone Giulio , De Martino Maria Cristina , Pivonello Rosario , Colao Annamaria , Damiano Vincenzo
Published: February 2025

Adrenocortical carcinomas (ACCs) are rare adrenal tumors that occur in hereditary syndromes or sporadically. Even in sporadic cases, somatic alterations in known susceptibility genes are often detected, emphasizing the growing role of genomic profiling. Recent evidence indicates that ACCs vary in their pathogenetic mechanisms, biochemical phenotype, metastatic potential, and prognosis. While surgery remains the primary treatment for localized ACCs, multiple therapeutic options exist for advanced or metastatic disease, although robust prospective data supporting a genomic profiling-oriented approach are still lacking. To enhance personalized management and improve outcomes in this molecularly complex disease, routine genetic testing for germline mutations along with comprehensive genome profiling for somatic mutations and cluster identification should become standard clinical practice. This review summarizes current evidence on ACC diagnosis and treatment, underscoring the need for a more personalized, cluster-based approach in clinical practice.
Driving Innovation Through Customer Relationship Management—a Data-Driven Approach
Authors: Lin Capacity Jung-Yi , Chen Chien-Cheng
Published: February 2025

Customer relationship management (CRM) is a key factor driving innovation and organizational growth. The present study investigated the relationship between data-driven CRM and innovation in Taiwan. We developed a theoretical framework involving CRM theory, innovation theory, and technology adoption theory to account for the cultural and organizational contexts of Taiwan to investigate this relationship. The study distributed questionnaires to employees and stakeholders within Taiwanese firms to understand their firms’ innovation and CRM practices. The results indicate that technology adoption and organizational culture have mediating effects and industry dynamics and organizational size have moderating effects on the relationship between data-driven CRM and innovation. That is, adopting new technology and having an organizational culture that supports innovation and company-wide collaboration can enhance the effects of implementing CRM practices. In addition, certain industries (e.g., the technology industry) are more likely to effectively leverage CRM practices to drive innovation, and although large organizations have more resources and can therefore more easily implement CRM systems, small and medium-sized enterprises can more quickly adapt and innovate on the basis of CRM insights. These findings highlight the importance of CRM in driving innovation and reveal key factors influencing the effectiveness of CRM in doing so.
Extending IEEE 802.15.4 for Wireless Process Control
Authors: Rusu Andrei , Dobra Petru , Hulea Mihai , Miron Radu
Published: February 2025

This paper explores the extension of the IEEE 802.15.4 standard for wireless process control, focusing on its application in industrial environments where secure and efficient data transfer is critical. The study addresses the limitations of existing industrial wireless protocols like ISA100 Wireless and Wireless HART, particularly their inability to fully support wireless control loops. A new approach is proposed, integrating state-of-the-art microcontrollers and transceivers to design a robust wireless control network (WCN) that ensures low latency and interference resistance. Key developments include the design and production of a custom development board, comparative analyses of hardware and software components, and the implementation of the TSCH (Time Slotted Channel Hopping) operating mode. The paper validates the solution through simulations and practical experiments, demonstrating its capability to maintain stable control loops in challenging industrial settings. Results indicate that the proposed network meets stringent industrial requirements, paving the way for broader adoption of wireless technologies in process control. This work highlights the feasibility of overcoming existing barriers to wireless control in industrial applications, contributing to the development of cost-effective and reliable systems.
Biocontrol Potential of Raw Olive Mill Waste against Verticillium dahliae in Vegetable Crops
Authors: Soultatos Stefanos K. , Chatzaki Anastasia , Karas Panagiotis A. , Papadaki Anastasia A. , Kalantzakis Georgios S. , Psarras Georgios , Goumas Dimitrios E. , Karpouzas Dimitrios G. , Markakis Emmanouil Alexandros
Published: February 2025

Verticillium wilt caused by the soil-borne fungus Verticillium dahliae causes severe losses to a broad range of economically important crops worldwide. Chemical disease management is ineffective; thus, alternative control strategies are needed. Olive-producing countries face the challenge of managing olive mill wastewaters (OMW) in an environmentally friendly and agronomically beneficial manner. The proper use of OMW supported by scientific research has been proposed as a valuable mean for successful disease management. In this respect, we tested whether soil application of raw OMW can protect vegetable crops against V. dahliae and investigated the potential disease suppressive mechanisms. OMW inhibited significantly fungal growth, sporulation, hyphae width, conidial and microsclerotial germination in-vitro, and these effects were dose-depended. Moreover, the addition of OMW in the soil provided sufficient protection of eggplant and tomato against V. dahliae in-planta. The high OMW-conferred protection of eggplant was gradually decreased, possibly due to the decreased phenolic content in OMW over time. Bioassays with sterilized soil substrate and OMW, along with isolated microbial strains revealed that soil- and OMW- originated microbes had no role in disease suppression. Moreover, split-root set ups suggested a non-systemic OMW-induced resistance mechanism. Root-drench application of OMW in eggplant and tomato plants did not cause significant alterations in the structure of the plant microbiome that could be associated with disease suppressiveness.
Inorganic Carbon Acquisition and Photosynthetic Metabolism in
Marine Photoautotrophs: A Summary
Authors: Beer Sven , Beardall John
Published: February 2025

The diffusive availability of CO2 for photosynthesis is orders of magnitude lower in water than in air. This, and the low affinity of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) for CO2, implies that most marine photoautotrophs (cyanobacteria, microalgae, macroalgae, and marine angiosperms or seagrasses) would be severely restricted were they to rely only on dissolved CO2 for their photosynthetic performance. On the other hand, the ~120 times higher concentration of bicarbonate (HCO3-) makes this inorganic carbon (Ci) form more available for utilisation by marine photosynthesisers. The most common way in marine macrophytes to utilise HCO3- is to convert it to CO2 within acidic micro-zones of diffusion boundary layers, including the cell walls, as catalysed by an outwardly acting carbonic anhydrase (CA). This would then generate an intra-chloroplastic (or for cyanobacteria intra-carboxysomal) CO2-concentrating mechanism (CCM). Some algae (e.g. the common macroalgae Ulva spp.) and most cyanobacteria and microalgae feature direct HCO3- uptake as the most efficient CCM, while others (e.g. some red algae growing under low-light conditions) may rely on CO2 diffusion only. We will in this contribution summarise our current understanding of photosynthetic carbon assimilation of submerged marine photoautotrophs, and in particular how their ‘biophysical’ CCMs differ from the ‘biochemical’ CCMs of terrestrial C4 and Crassulacean acid metabolism (CAM) plants (for which there is very limited evidence in cyanobacteria, algae and seagrasses).
Enhancing Malware Analysis using Data Visualization through Shared Code and Attribute Analysis
Authors: Vashista Narayandas Sai Ramana , Patro K Abhimanyu Kumar
Published: February 2025

Malware analysis is a crucial area of cybersecurity, focusing on identifying, categorizing, and studying malicious software to prevent it from posing a threat to computer systems. This paper introduces a new approach to malware analysis by integrating two methods, Shared Code Analysis (SCA) and Shared Attribute Analysis (SAA). The SCA component searches for similarities in code within multiple malware samples using the MinHash techniques. The SAA component uses the Jaccard indexing technique to analyze and approximate similarity based on malware samples’ attributes. The visualization is implemented using NetworkX with Graphviz, where nodes represent individual malware samples and edges represent close relations. The visualization is provided as a PNG file, demonstrating the grouping of related malwares according to their attributes. A real-life case based on malware samples from GitHub repositories illustrates the application of the proposed methodology. The integration of the Jaccard Index and MinHash provides an extensive method for covering the relationships among malware and enhancing detection and categorization steps. This approach not only provides a better understanding of code patterns, but it also helps visualize attribute-based maximum similarity, making it a valuable tool for researchers and cybersecurity professionals.
Caracterización del voto en la Ciudad de México
Authors: Fernandez Poncela Anna Maria
Published: February 2025

Voting is important for elections and in democratic systems of government. The consideration of it varies according to societies, countries, times, groups and people. Its study also considers different approaches. In this case, a general approach is made to the conception and assessment of voting according to citizens. Specifically, its importance, respect, trust, information, reasons and motives. All this through some questions from a pre-election survey, and fundamentally, through the testimony collected in interviews conducted in Mexico City, before and after the electoral call on June 2, 2024. This in order to obtain direct testimonies from people, their perception and opinion, expectations and experiences, imaginary configurations and political behaviors, in short, their reflection and feeling on the subject. As a finding, it is possible to say that voting is very important as information is, elections are not respected and trusted, the main reasons for exercising it are the right and democracy, and the reasons, the program and change.
Real-Time Linkage of Public-Facing Jail Registers and Syphilis Testing and Treatment Monitoring Data, Washington State, 2023–2024
Authors: Erly Steven J. , Hill Leighton O. , Gavigan Kiara B. , Haecker Kari L. , Amiya Rachel M.
Published: February 2025

Between June 22, 2023, and January 22, 2024, we implemented scripts to collect public-facing correctional facility rosters and used a matching algorithm to link these data to unresolved syphilis investigations in Washington state. We reviewed the results and sent alerts to the assigned disease intervention specialist. We captured data from 60 of Washington’s 69 correctional facilities and linked 54 individuals to testing or treatment. Fifty-eight percent of individuals had been unlocated for 60 days or more and may not have been found otherwise. ( Am J Public Health. 2025;115(3):282–286. https://doi.org/10.2105/AJPH.2024.307911 )
Improving Participation in HIV Preexposure Prophylaxis via an Informatics Approach—a Process-Improvement Project
Authors: Mandia Jeremy J. , Keltner Case H. , Haynes Robert C. , Cruz Lisa , Solveson Keith , Mease Luke E.
Published: February 2025

With this project, we aimed to re-engage military health care beneficiaries with expired HIV preexposure prophylaxis prescriptions at Madigan Army Medical Center (Tacoma, WA). We identified prescriptions expired between August 2022 and August 2023 via electronic health records, then called patients to assess HIV risk and arrange follow-up. Of those with clinical indications, 80% agreed to re-engage with preexposure prophylaxis services, increasing the number of patients receiving preexposure prophylaxis at our institution by 30%. Systematic electronic health records query can reduce nonadherence when active case management is not feasible. ( Am J Public Health. 2025;115(3):287–291. https://doi.org/10.2105/AJPH.2024.307919 )
Historical Trace of The Spice Road as an Economic Center Indonesian Trade and Cultural Heritage
Authors: Siregar Aisyah Astinadia
Published: February 2025

This research aims to explore the history of the Indonesian spice route as part of Indonesia's maritime cultural heritage and Indonesia's role in the spice trade route. The method used in this research is a descriptive qualitative approach with literature studies, utilizing various sources from books, journals and articles as well as ethnography and oral interviews. The results of the research show that the trade network connecting the eastern and western hemispheres of the world is known as the spice route and its impact. towards the development of local cultural identity of Indonesian society. The spice route not only refers to the trade and shipping route for spice products, but also as a cultural heritage whose traces can still be found, such as in culinary, art, medicine, clothing, traditions and even art. At that time, merchandise such as cinnamon, pepper, cloves, nutmeg, sandalwood, rice, cotton and others were traded. This route is a symbol that connects the maritime civilization of the archipelago which is Indonesia's national pride so that it can provide a new contribution to understanding the complexity of the interaction between economic factors and cultural heritage in shaping the historical landscape of the archipelago.
How Household Tourism Expenditure in Indonesia? A QUAIDS Model Analysis
Authors: Rosyadi Imron , Avrillia Salsabila
Published: February 2025

Tourism is a sector in Indonesia that has experienced rapid development in the last decade. This sector provides new hope for the emergence of new sources of economic growth when the economy is experiencing a slowdown. This study aims to estimate the income elasticity and expenditure pattern household on tourism in Indonesia. The data used is the publication of the Indonesian Family Life Survey (IFLS). To obtain comprehensive estimation results, this study uses the Quadratic Almost Ideal Demand System (QUAIDS) approach which is currently the standard in household demand estimation systems. Four groups of expenditure types were examined: personal goods, household goods, tourism, and transportation. The results showed that the largest household expenditure was transportation followed by personal goods, household goods, and tourism. However, the largest household income elasticity is tourism, followed by household goods, personal goods and transportation. This is because when household income is constant, the household expenditure budget is allocated to transportation, personal goods and household goods more than tourism. Meanwhile, when income increases, households will allocate their budget for tourism, because expenditure on transportation, personal goods, and household goods has reached the point of maximum utility. And then, other finding show that income elasticity is relatively elastic. This suggests that improvements in household income have the potential to increase expenditure on the tourism sector. This has important implications in terms of public policy, as it makes it possible to explore how tourism policy interacts with household expenditure. Thus, the government and related institutions can obtain consideration from income elasticity and expenditure pattern household in making policies in the tourism sector.
Baseline Temperature Variability Shaping Geographical Distribution of Future Hot Extremes under Anthropogenic Warming
Authors: Ma Xiaohui , Tang Zhili , Zhou Shenghui , Wu Lixin , Cai Wenju , Jing Zhao , Chen Zhaohui , Gan Bolan
Published: February 2025

Hot extreme events are among the most devastating disasters affecting human health and the natural environment. While there is broad consensus on an increasing severity of these events under anthropogenic warming, their geographical distribution exhibits substantial spatial heterogeneity, and its driving factors remain uncertain. Here, utilizing an eddy-resolving high-resolution climate model alongside multiple simulations from Coupled Model Intercomparison Project Phase 6, we find baseline temperature variability as a key factor shaping the global distribution of projected hot extremes, with over 80% of the global increase in hot extremes anticorrelated with baseline temperature variability. We further demonstrate that the baseline temperature variability is anchored by persistent land-atmosphere coupling, which endures over century timescales and sustains the spatial heterogeneity of future hot extremes. Our findings suggest that baseline temperature variability could serve as a potential indicator for future hot extreme distribution, offering valuable insights for developing targeted adaptation strategies and improving regional resilience.
Multi-modal AI for Opportunistic Screening, Staging and Progression Risk Stratification of Steatotic Liver Disease
Authors: Gao Yuan , Li Chun Li , Chang Wan Xing , Du Bai , Ye Xianghua , Xia Ying Da , Guo Heng , Zhang Xiao Ming , Liu Wei , Bai Ruo Bing , Li Bei Bei , Hong Yang , Yao Jiawen , Lu Le , Cao Kai , Yeo Yee Hui , Chen Jun , Li Jie , Yan Ke , Hou Yang , Zhang Ling , Shi Yu
Published: February 2025

The prevalence of steatotic liver disease (SLD) is rising globally, presenting a significant public health challenge. While non-contrast computed tomography (CT) scans hold promise for the opportunistic detection of SLD, their full potential has not been systematically explored. Clinical indicators, such as serum data, are crucial for monitoring the progression of SLD. We introduce a novel Multimodal AI for Opportunistic Steatotic Liver Disease Screening (MAOSS), which integrates demographic data, serum tests, conventional CT biomarkers, and deep learning-derived CT image features to enhance model performance and explainability. MAOSS employs an innovative learning strategy, trained on a large-scale dataset (n = 1,783) encompassing both histopathologically-confirmed SLD and radiologically-reported steatosis cases. The model underwent extensive retrospective validation using steatosis grades derived from both histology and MRI-PDFF across internal and external datasets (n = 913), as well as real-world patient data (n = 18,504). It accurately detected mild to severe steatosis (≥ S1) with AUCs ranging from 0.903 to 0.929. Notably, MAOSS significantly improved the overall AUC for radiologists (n = 11) from 0.709 to 0.798 (p < 0.001). Furthermore, MAOSS was applied to optimize the standard clinical pathway for a simulated primary risk screening of SLD patients (n = 1,192), resulting in the identification of 31% more patients at risk of steatohepatitis and liver fibrosis progression, highlighting its potential to enhance SLD detection and management.