bluuebunny/crossref_metadata_2025 huggingface dataset:
Faíscas e brilhos na escuridão: o neobarroco no cinema berlinense nos anos 1920
Authors:   Universidade Federal de São Paulo, Varolli Renan de Andrade
Published: May 2023

Pretendemos elaborar certas transferências de determinado sistema da cultura ocidental chamado barroco para o ambiente da cidade alemã de Berlim nos anos 1920, sendo suscitadas através de análises fílmicas de trechos únicos e contínuos de duas películas produzidas ali e exibidas pela primeira vez em 1927: Berlim, Sinfonia da Metrópole (Berlin: Die Sinfonie der Großstadt, Walter Ruttmann, 1927) e Metrópolis (Metropolis, Fritz Lang, 1927). No primeiro filme, nosso foco será no Quinto Ato (V. Akt), parte que lhe encerra e mostra gravações referentes ao que a noite berlinense expunha naquela época. Já no segundo, concentraremo-nos na sequência da primeira aparição de Yoshiwara (clube noturno da cidade ficcional em que a fita se passa).
A arte na publicidade: paintings
Authors:   Universidade de São Paulo, Valenzuela Sandra Trabucco
Published: May 2023

O presente trabalho examina o vídeo publicitário do whisky Johnnie Walker, intitulado Paintings, dirigido por Bobby Proctor, concebido pela agência BBH London e produzido pela Aardman Studios (2005) , que propõe a releitura de pinturas de artistas que vão do romantismo ao surrealismo. Identificam-se as obras e os artistas que atuam como referências intertextuais, o leitmotiv que une semanticamente a narrativa, a história do produto e a proposta fílmica. O contexto histórico/ cultural/artístico das obras citadas é fundamental para compreender a peça publicitária, pois justificam a sua escolha, comprometendo a apreensão das ideias norteadoras desta proposta que integra arte, história, narrativa audiovisual e publicidade.
O abade Suger sobre os vitrais de Saint-Denis
Authors:   Universidade de São Paulo, Santos Selene Candian dos
Published: May 2023

No texto que a literatura costuma denominar De Administratione (ca. 1144-1149), Suger, abade de Saint-Denis (1122-1151), descreve o aumento nas rendas de Saint-Denis, as reformas realizadas na estrutura da igreja abacial e os ornamentos adquiridos e restaurados sob sua administração. Esse texto foi e é de grande interesse para diversos historiadores da arte – como Erwin Panofsky, Peter Kidson, Conrad Rudolph e Jean-Claude Bonne – já que as reformas realizadas e descritas por Suger foram identificadas pela História da Arte, muitos séculos depois, como o início da arquitetura gótica.
História da arte e história do paisagismo no Brasil: inter-relações na análise de projetos paisagísticos
Authors:   Universidade Nove de Julho em São Paulo, Aragão Solange de
Published: May 2023

Para construir a História do Paisagismo no Brasil, que se amplia de fato a partir do século XIX, é necessário retroceder sempre aos séculos anteriores, para explicar por que, durante os três primeiros séculos de colonização, foram raríssimos os projetos paisagísticos em território nacional.
Simulation of System Dynamics for Improving The Quality of Paddy Production in Supporting Food Security
Authors: Aprillya Mala Rosa , Suryani Erma
Published: May 2023

Background: The food security policy is an effort to ensure stable food availability and stable access of the community to food. As the population increases, this will affect the fulfillment of food needs in the future. Therefore, increase in rice production is needed to support food security.
Objective: Conduct an analysis of the factors affecting the quality of rice production by using a dynamic system simulation that can be used as a basis for formulating policy strategies.
Method: Simulation using System Dynamics (SD) is a method used to study and analyze complex systems by modeling non-linear behavior. Then several scenarios were carried out for the best decision-making using a computer.
Result: The results of the scenario show that increasing the quality of paddy production in order to meet food needs in the future is doable by boosting the rendement of paddy as it will upgrade rice production which  will contribute greatly to rice production.
Conclusion: From the simulation results, the  study can be used to increase the quality of rice production to maintain food security by improving the harvesting mechanism to increase yields. For further research, the use of Smart Agriculture can be considered to increase production of rice.
 
Keywords: Food security, Rice production, Rice production, System dynamics
BEVACIZUMAB EFFECT ON EXPRESSION OF COLLAGEN TYPE I AFTER TRABECULECTOMY
Authors: Shinta Arta Wiguna Shinta
Published: May 2023

Objective to determine the effect of bevacizumab as an antifibrotic agent on collagen density, collagen thickness and collagen type I after trabeculectomy in rabbit. Materials and methods : Sixteen male New Zealand white rabbits divided by two groups, 8 rabbits in control group and 8 rabbits in treatment group. Control group underwent trabeculectomy and injection of balanced salt solution. Treatment group underwent trabeculectomy and subconjunctival injection of bevacizumab (1.25mg, 25mg/mL). They were terminated on 14 postoperative days. Masson Trichrome were performed to evaluate collagen collagen density, collagen thickness. Immunohistochemistry using a monoclonal antibody to collagen type I was performed to evaluate collagen type I expression. Results This study showed the density of collagen fibers decreased and statistically significant in the treatment group (p = 0.075, p 0.05). Expression of type I collagen obtained a decrease in the treatment group compared to BSS group (p = 0.006, p<0.05). Conclusion Bevacizumab reduces bleb fibrosis by inhibition of angiogenesis and accumulation of extracellular matrix. Postoperative subconjunctival injection of bevacizumab may limiting scar tissue formation at the site of trabeculectomy by blocking collagen synthesis.
Cardiovascular aging: from cellular and molecular changes to therapeutic interventions
Authors: Vakka Angeliki , Warren Junco S. , Drosatos Konstantinos
Published: May 2023

Progressive age-induced deterioration in the structure and function of the cardiovascular system involves cardiac hypertrophy, diastolic dysfunction, myocardial fibrosis, arterial stiffness, and endothelial dysfunction. These changes are driven by complex processes that are interconnected, such as oxidative stress, mitochondrial dysfunction, autophagy, inflammation, fibrosis, and telomere dysfunction. In recent years, the advances in research of cardiovascular aging, including the wide use of animal models of cardiovascular aging, elucidated an abundance of cell signaling pathways involved in these processes and brought into sight possible interventions, which span from pharmacological agents, such as metformin, sodium-glucose cotransporter 2-inhibitors, rapamycin, dasatinib and quercetin, to lifestyle changes.
Space Theory
Authors: Chen S.
Published: May 2023

The author introduces a novel theoretical framework that suggests matter and energy are both converted from curved space. In Space Theory, gravitation is generated by the flow of space, instead of being transmitted by the graviton as in String Theory. This theory also suggests that Newton's gravitational constant, denoted as G, may not be truly constant but could vary over time. The equivalent equation of space is S=Ec2=mc4, and for the gravitation of hollow sphere space, the equation is Sμν=4πGm=(4/3)π((r+a)3-r3).
The Dynamic Structural-Material Complexes of the Earth’s Crust
Authors: Копылов Аркадий
Published: May 2023

Аннотация. Периодически формируются самоподобные динамические структурно-вещественные комплексы (СМК) из состава Солнечной системы за период около 4,5 млрд лет земной коры, развития Земли в условиях самоорганизации. Синхронные или близкие во времени ряды генетически или парагенетически связанных магматических, рудно-минеральных, метасоматических, осадочных образований, их структур и других сопутствующих им процессов, включает в себя каждый комплекс (ГМК). Каждый комплекс в своем формировании ограничен во времени и пространстве, по проявлению признаков самопроизвольного динамического процесса; распространяется в объеме Земли в определенный исторический период; формирует состав и строение земной коры на этом этапе, определяя ее полициклическое развитие. Количество циклов около 14,
Plan for Constructing DataDiscoveryLab: Creating DataBases for Well-Rounded Searches
Authors: Keskinoglu Elbek
Published: May 2023

The abundance of information in academic articles, reports, and studies can make it challenging for researchers to gain insights from the existing literature. To address this issue, there is a growing demand for tools that can help researchers effectively parse and analyze large volumes of data. One such tool is DataDiscoveryLab, a software system that utilizes computer vision algorithms and NLP techniques to parse academic articles into text and figures, creating three separate databases. These databases allow researchers to quickly identify articles that may be relevant to their research questions, gain a deeper understanding of the research presented, and analyze visual data. The integration of article mining and computer vision in the DataDiscoveryLab software system provides researchers with a powerful tool for navigating the vast amount of scientific literature available today. Yet, as we will discuss in the latter papers these databases’ purpose is to create a bridge between researchers’ data and practically unlimited scientific publications. Yet, in this article, we will discuss how we plan to do that, and our efforts on integrating deep learning modes. After all, unlike already existing AI models, DataDiscoveryLab can be their combination and the first Generative AI in academia that can encompass every part of the natural sciences.
Research on Construction and Application of Aircraft Fault Knowledge Graphs
Authors: Tang Xilang , Chi Guo , Cui Lijie , Ip Andrew W.H. , Yung Kai Leung , Xie Xiaoyue
Published: May 2023

When an aircraft malfunctions, quickly and accurately identifying the faulty unit is essential for ensuring normal operation. Unfortunately, maintenance engineers often struggle to acquire the necessary fault-related knowledge due to poor management and utilization of aircraft fault documents. To address this issue, we introduce knowledge graph technology into the field of aircraft fault diagnosis, exploring its construction and application for effective knowledge management. Our work starts by analyzing the critical knowledge elements required for aircraft fault diagnosis and designing a schema layer for fault knowledge graphs. We then we then combine deep learning and heuristic rules to extract fault knowledge from both structured and unstructured data, enabling the construction of aircraft fault knowledge graphs. Finally, we develop a fault question-answering system based on fault knowledge graphs that can accurately give solutions to questions posed by maintenance engineers. Our practice demonstrates that knowledge graphs provide an effective means of managing aircraft fault knowledge, assisting engineers in locating fault reasons accurately and quickly.
Review of Research Progress in the Case of Non-conventionally Treated Steel with Plasma Nitriding Applied after Thermomagnetic Treatment
Authors: Papadatu Carmen-Penelopi
Published: May 2023

The paper focuses on two unconventional magnetic field-based treatment regimes applied to an alloyed steel before applying a thermochemical treatment. This study was conducted in order to improve the behavior of the chosen material during the wear process. Increasing the wear resistance and the micro-hardness of the superficial layer obtained from the treatments are a priority, as well as improving the mechanical properties of a Cr-Mo alloyed steel. Thermomagnetic treatment, applied before plasma nitriding treatment, improves the mechanical properties of the base material, especially in the case of a steel with a considerable chromium content (1,02%). This paper is a review of my own researches in the last years.
Variable Speed Control in PATs: Theoretical, Experimental and Numerical Modelling
Authors: Plua Frank , Sánchez-Romero Francisco-Javier , Hidalgo Victor , López-Jiménez Petra Amparo , Pérez-Sánchez Modesto
Published: May 2023

pump as turbine (PAT); computational fluid dynamics; variable rotational nominal speed; OpenFoam.
Development and Validation a High-performance Liquid Chromatography-tandem Mass Spectrometry Method to Determine Promethazine and its Metabolites in Edible Tissues of Swine
Authors: Wen Dehui , Shi Rong , He Haiming , Chen Rundong , Zhang Yingzi , Liu Rong , Chen Hong
Published: May 2023

To determine promethazine (PMZ) and its metabolites promethazine sulfoxide (PMZSO) and monodesmethyl-promethazine (Nor1PMZ) in swine muscle, fat, kidney, and liver, a sample preparation and high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis method were established and validated. The sample was extracted with 0.1% formic acid-acetonitrile, and the extract was purified with acetonitrile-saturated n-hexane. After concentration by rotary evaporation, the extract was re-dissolved in 0.1% formic acid-water and acetonitrile (80:20, v/v). The HPLC-MS/MS column used was a Waters Symmetry C18 (100 mm × 2.1 mm i.d., 3.5 μm), with 0.1% formic acid-water and acetonitrile as the mobile phase, and the target compounds were determined by positive ion scan and multiple reaction monitoring. PMZ and Nor1PMZ were quantified with deuterated promethazine (PMZ-d6) as the internal standard, while PMZSO was quantified by external standard method. The limits of detection (LOD) and limits of quantification (LOQ) of PMZ and PMZSO in muscle, liver, and kidney spiked samples were 0.05 μg/kg and 0.1 μg/kg, respectively, while those of Nor1PMZ were 0.1 μg/kg and 0.5 μg/kg, respectively. The LOD and LOQ of analytes in fat spiked sample were 0.05 μg/kg and 0.1 μg/kg, respectively. The sensitivity of this method reaches or exceeds its presented in previous reports. The analytes PMZ and PMZSO showed good linearity within the range of 0.1 μg/kg to 50 μg/kg, while Nor1PMZ showed good linearity within the range of 0.5 μg/kg to 50 μg/kg, with correlation coefficients (r) greater than 0.99. The recoveries of the target compounds in the sam-ples were between 81.73% and 107.17%, and the precision ranged from 1.78% to 10.47%. This study developed for the first time an HPLC-MS/MS method for the determination of PMZ and its metabolites PMZSO and Nor1PMZ in four swine edible tissues, comprehensively covered target tissues of monitoring object, which is applicable for monitoring veterinary drug residues in ani-mal-derived foods and ensuring food safety.
Belantamab Mafodotin: From Clinical Trials Data to Real Life Experiences
Authors: Morè Sonia , Offidani Massimo , Corvatta Laura , Petrucci Maria Teresa , Fazio Francesca
Published: May 2023

Despite the recent approval of novel immunotherapies, as immunomodulatory drug, proteasome inhibitors and anti-CD38 monoclonal antibodies, Multiple Myeloma (MM) remains incurable and the acquisition of triple-refractoriness leads to really dismal outcomes, in even earlier lines of therapy. More recently, innovative therapeutic strategies targeting B cell maturation antigen (BCMA), highly expressed on the plasma cell surface, are drawing different future landscapes in terms of effectiveness and outcomes. Belantamab Mafodotin, a first-in-class anti-BCMA antibody drug conjugates, demonstrated good efficacy and safety profile in triple-refractory patients in the phase 2 DREAMM-2 trial and it was approved for the treatment of MM triple-exposed patients with >4 prior lines of therapy. Here, starting from Belantamab Mafodotin clinical trials also exploring combination studies and different schedules in order to improve its efficacy and toxicity, we focused on real life experiences all over the world, which have confirmed clinical trial data and encourage further Belantamab Mafodotin investigations
Feasibility, Uptake, and Results of COVID-19 Antigen Rapid Diagnostic Tests Among Refugees and Migrants in a Pilot Project in Northwest Syria
Authors: Ghawji Hassan , ALYOUSFI Mohamad Nihad , Satyanarayana Srinath , Wilson Nevin , Tomeh Laila , Alkhellov Hussam , Hasan Sali , Sarin Sanjay , Kao Kekeletso
Published: May 2023

1) Background: Northwest Syria (NWS), is a conflict-affected and unstable area. Due to its limited health infrastructure, accessing advanced COVID-19 testing services is challenging. COVID-19 antigen rapid diagnostic tests (Ag-RDTs) have the potential to overcome this barrier. Therefore, a pilot project was implemented to introduce Ag-RDTs in this setting aiming to a) describe the feasibility, uptake, and results of Ag-RDTs; and b) identify facilitators and barriers to Ag-RDTs testing. 2) Methods: A cross-sectional study design involving secondary analysis of data collected during the project’s monitoring was developed. A local NGO implemented 25,000 Ag-RDTs cross boarder through trained community health workers. 3) Results: A total of 27,888 persons were found eligible and enrolled, of which 24,956 (89.5%) consented to test and 121 (0.5%) were found positive. Highest positivity was observed among those with severe COVID-19 symptoms (12.7%), those with respiratory illnesses (2.5%), persons enrolled at Afrin Hospitals (2.5%), and healthcare workers (1.9%). A non-random sample of 236 people underwent confirmatory rt-PCR test. Accordingly, observed sensitivity, specificity, positive and negative predictive values, were 80.0%, 96.1%, 91.4% and 90.3%, respectively. Key encountered challenges included obtaining informed consent and conducting confirmatory rt-PCR testing. 4) Conclusion: This project demonstrated great feasibility utilizing Ag-RDTs as a screening/diagnostic tool for COVID-19 infections with nearly 90% uptake. Considering the high specificity and negative predictive values and the higher positivity rates among severe COVID-19 symptomatic, embedding Ag-RDTs into COVID-19 testing strategies for ruling out and in COVID-19 infections would hold a great advantage.
Two Fe-Zr-B-Cu Nanocrystalline Magnetic Alloys Produced by Mechanical Alloying Technique
Authors: Daza Jason , Ben Mbarek Wael , Escoda Lluisa , Saurina Joan , Suñol Joan-Josep
Published: May 2023

Fe rich soft magnetic alloys are candidates for applications as magnetic sensors and actuators. These alloys can also be added to hard magnetic compounds to obtain spring magnets. In this work we produce two nanocrystalline Fe-Zr-B-Cu alloys by the powder metallurgy powder technology of mechanical alloying. The increase of the boron content favors the reduction of the crystalline size. Thermal analysis (by differential scanning calorimetry) shows at temperatures between 450 and 650 K wide exothermic processes, associated with the relaxation of tensions of the alloys produced by milling. At high temperatures, a main crystallization peak is found. The apparent activation of this process was determined by Kissinger and isoconversional methods. The values are compared with those found in the scientific literature. Likewise, adapted thermogravimetry permits to determine the Curie temperature. The functional response has been analyzed by hysteresis loop cycles. According to the composition, the decrease of the Fe/B ratio diminishes the magnetic soft behavior.
Phenylalanine Losses in Neutralization Dialysis: Modelling and Experiment
Authors: Kozmai Anton , Porozhnyy Mikhail , Gil Violetta , Dammak Lasaad
Published: May 2023

A non-steady state mathematical model of amino acid (phenylalanine (Phe)) and mineral salt (NaCl) solution separation by neutralization dialysis (ND) carried out in a batch mode is proposed. The model takes into account the characteristics of membranes (thickness, ion-exchange capacity and conductivity) and solutions (concentration, composition), as well as the flow rate of the solution in the dialyzer compartments. As compared to previously developed models, the new one considers the local equilibrium of Phe protolysis reactions in solutions and membranes and, also, the transport of all the phenylalanine forms (zwitterionic, positively and negatively charged) through membranes. A series of experiments on ND demineralization of NaCl and Phe mixed solution was carried out. In order to minimize Phe losses, the solution pH in the desalination compartment was controlled by changing the concentrations of the solutions in the acid and alkali compartments of the ND cell. The validity of the model was verified by comparison of simulated and experimental time dependencies of solution electric conductivity and pH, as well as the concentration of Na+, Cl– ions and Phe species in the desalination compartment. Based on the simulation results, the role of Phe transport mechanisms in the losses of this amino acid during ND was discussed.
Did the Addition of Olive Cake in the Finishing Diet of Bísaro Pigs Affect the Volatile Compounds and Sensory Characteristics of Dry-Cured Loin and Dry-Cured “Cachaço”?
Authors: Leite Ana , Vasconcelos Lia , Ferreira Iasmin , Domínguez Rubén , Pateiro Mirian , Rodrigues Sandra , Pereira Etelvina , Campagnol Paulo , Perez José Angel , Lorenzo Jose M. , Teixeira Alfredo
Published: May 2023

This study was conducted to determine the effect of different types of olive cake (five treatments) in the diet of Bísaro pigs on the volatile compounds and sensory characteristics in the dry-cured loin and dry-cured “cachaço” (2 processed meat products). The treatments applied are based on the type of extraction and this may imply differences in their water and fat content. Eighty com-pounds were identified, and grouped into eight chemical classes: hydrocarbons, aldehydes, es-ters, alcohols, ketones, acids, furans, and other compounds. Aldehydes and alcohols were the ma-jor groups of compounds, representing 57.06-66.07 % and 68.67-75.61 % for the loin and “cacha-ço”, respectively. There were no significant differences between treatments for any of the volatile compounds identified. The major aldehydes were hexanal, heptanal, pentanal, and propanal. These compounds were significantly higher (p<0.001) in “cachaço”. This significant difference be-tween the two types of dry-cured products is directly related to the amount of total fat content. The major alcohols were 2.3-butanediol, 1-octen-3-ol, 1-butanol, 3-methyl, 1-hexanol, benzyl-alcohol and glycidol. Except for compounds 2,3-butanediol and benzyl-alcohol, the majority in this group are significantly different in terms of the type of dry-cured product. As for the sensory evaluation, for both dry-cured products, the trained tasters did not detect significant differences between the different treatments, which is in line with the results obtained for volatile compounds.
Impact of Insecure Land Tenure on Sustainable Housing Development: A Case Study of Urban Housing Lands in the Republic of Benin, West Africa
Authors: Ekpodessi Serge G.N. , Nakamura Hitoshi
Published: May 2023

This study focuses on land tenure in an urban environment. Specifically, it intends to elucidate the influence of land tenure security on access to housing in urban communities. The conurbation of Grand Nokoué, which is an agglomeration of five cities in the Republic of Benin, West Africa, captures attention due to its particular features as a developing city. Based on the literature, this study outlined three major factors of insecure land tenure, namely, lack of recognition by authorities, lack of protection from eviction or expulsion, and informal community-based rights. In addition, we examined four characteristics of relevant housing issues, namely, the development of shantytowns, the multiplicity of precarious housing, the loss of housing for the development of public projects, and exposure to house demolition under judicial decision to formulate our hypotheses. The results of a field observation and semi-structured interviews supported the hypotheses and demonstrated that the legal access to land, the protection of the population from anarchic eviction and informal community-based rights may positively influence the development of sustainable urban housing.
Micro-Nano-Plastics in the Atmosphere: Methodology for Sampling
Authors: Logvina Yuliya , Casado Isabel M. , Ribeiro Helena , Silva Luís Pinto da , Rodrigues Pedro , Leitão João , Silva Joaquim Esteves da
Published: May 2023

Micro-nano-plastics (MNPs) are an important constituent of atmospheric aerosol. However, there is still no standard procedure for their sampling and size fractionation, which is an obstacle to the aggregation and critical analysis of results obtained by different research groups. This review focuses on the sampling and fractionation methodologies used for MNPs. Moreover, a straightforward optimized methodology for the sampling and fractionation is proposed.
Odor Perception and Descriptions of Rose-Scented Geranium Pelargonium graveolens ‘Dr. Westerlund’ – Sensory and Chemical Analyses
Authors: Wendin Karin , Pálsdóttir Anna Maria , Spendrup Sara , Mårtensson Lennart
Published: May 2023

The positive impact of nature on human health has been explored by researchers. Although studies have indicated that olfaction and odors have an impact on both memory and health, re-search on the odor perception in relation to perceived health is scarce. A recent study found that the naturenatural scent from stem cuttings and potted plants of a specific rose-scented geranium Pelargonium
graveolens, ‘Dr. Westerlund,’Westerlund’ had positive effects on stress-related mental disorders. reduction. Essential oils from many
Pelargonium species, in particular ‘Dr. Westerlund’, are known to have phytochemical properties and pharmacological activities. No study has, so far, explored and identified the chemical com-pounds and the sensory perception of these compounds in stem cuttings and the potted ´Dr. Westerlund´ plantplants. Such knowledge would be an important
contribution forto an increased understanding of the effects of plants’ chemical odor properties on human well-being and link this to the expressed perceived scents. Resulting sensory profiles of P.This study aimed to identify the sensory profile and suggest responsible chemical compounds of Pelargonium graveolens ´Dr. Westerlund´ as a potted plant and as stem cuttings were reported, as well as´. The sensory and chemical analysis results revealed sensory profiles of Pelargonium graveolens ´Dr. Westerlund´s, and suggestions for the chemical compounds that are attributed to the sensory profiles. Further studies are recommended to investigate the odor experience of scented pelargonium species in relation to various levels ofcorrelation between volatile com-pounds and possible stress hormones. reduction in humans.
Perspectives on Aging and Quality of Life
Authors: Noto Shinichi
Published: May 2023

As the world's population ages and the resulting health problems become more serious, medical and health policies in developed countries are focused on how to prevent and treat the diseases of the aging population and how to maintain their quality of life. Typical age-related diseases include deafness, cataracts, osteoarthritis, chronic obstructive pulmonary disease, diabetes mellitus, and dementia. Although the mechanisms by which these diseases develop differ, they are all caused by the accumulation of molecular and cellular damage over time. In addition, age-related diseases can cause a decline in physical and mental functions and the ability to perform activities of daily living, as well as the loss of roles in society and a sense of fulfillment in life. Therefore, there is a need for treatment and measures to accurately grasp and maintain their quality of life.
Assessment of Thermal and Mechanical Properties of Cement-Based Materials—Part 2: Perlite Concrete
Authors: Isopescu Dorina Nicolina , Cojocaru Alexandra , Baciu Ioana-Roxana , Maxineasa Sebastian George , Petre Sergiu George
Published: May 2023

There is an international concern for reducing energy consumption and protecting environment by application of circular economy principles in the construction industry. The thermal resistance of concrete plays a significant role in the energy efficiency of a building, and this can be improved by using concrete products with high thermal resistance. This study analyzes the influence of perlite, as an addition, on the physico-mechanical properties of concrete, with the aim of identifying perlite concrete products that will respond to the improvement of the heat transfer resistance of the building envelope. The study examines the effect of replacing different amounts of concrete aggregates with perlite in percentages of 10%, 20%, 30% and 100%. The results show that the replacement of sand with perlite improves the thermal performance of concrete, but its mechanical properties are negatively affected. The research carried out highlighted that perlite can be successfully introduced in the production of concrete blocks used for external non-bearing walls pannels, the outstanding feature being the reduction of energy consumption in buildings. Overall, the paper identifies an efficient and environmentally friendly way of using perlite in the construction industry, improving the energy performance of buildings, and reducing the environmental impact of construction wastes.
Sustainable Sawdust/Eucalyptol Absorption Matrix for Odor Slow-Release in Plywood Floor
Authors: Logvina Yuliya , Fernandes Sónia , Silva Luís Pinto da , Silva Joaquim Esteves da
Published: May 2023

A sustainable matrix based on eucalyptol essential oil/sawdust was developed and applied on one-sided laminated plywood. This finish aims to serve as a eucalyptol odor slow release. Eucalyptol odor release was monitored with gas chromatography coupled with a flame ionization detector (GC – FID: Limits of Detection and Quantification of 0.70 g/m3 and 2.11 g/m3, respectively, and with linearity up to 18.6 g/m3). Measurement of the eucalyptol odor released was performed during a six-month period and it was found that the release followed a first-order exponential decay with a decay rate constant of 0.0169 per day. The half-life was determined to be of 48 days. The granulometry and particle size porosity of sawdust were analyzed by Scanning Electron Microscopy. Sawdust size fraction between 112 – 200 μm showed best eucalyptol absorption capacity with 1:3 masses ratio (sawdust:eucalyptol). The time capacity of eucalyptol release depends of composite eucalyptol – sawdust quantity. Where this relation was determined: 15.0 grams of composite eucalyptol-sawdust by 0.8 mm diameter aperture gave 6 months of eucalyptol release, that was considered very positive, understanding high volatility of eucalyptol and a small quantity of composite for further products. The new product is characterized by a carbon footprint (considering the industry frontiers) of 5.94 kg CO2eq/m2 of plywood floor.
Using Machine Learning to Information Classification Related on Child-Rearing of Infants from Twitter
Authors: Zipaer Mayinuer , Yoshida Minoru , Matumoto Kazuyuki , Kita Kenji
Published: May 2023

It is difficult to obtain necessary information accurately from Social Networking Service (SNS) while raising children, and it is thought that there is a certain demand for the development of a system that presents appropriate information to users according to the child's developmental stage. There are still few examples of research on knowledge extraction that focuses on childcare. This research aims to develop a system that extracts and presents useful knowledge for people who are actually raising children, using texts about childcare posted on Twitter. In many systems numbers in text data are just strings like words and are normalized to zero or simply ignored. In this paper, we created a set of tweet texts and a set of profiles created according to the developmental stages of infants from "0-year-old child" to "6-year-old child". For each set, we used Support Vector Machine (SVM), and Bidirectional Encoder Representations from Transformers (BERT), a neural language model, to construct a classification model that predicts numbers from "0" to "6" from sentences. The accuracy rate predicted by the BERT classifier was slightly higher than that of the SVM classifier, indicating that the BERT classification method was better.
Low-Profile Broadband Dual-Polarized Dipole Antenna for Base Station Applications
Authors: FENG Hao , LI Mengyuan , ZHANG Zhiyi , FU Jiahui , ZHANG Qunhao , ZHAO Yulin
Published: May 2023

A low-profile broadband dual-polarized antenna is investigated for base station applications. It consists of two orthogonal dipoles, fork-shaped feeding lines, an artificial magnetic conductor (AMC), and parasitic strips. By utilizing the dispersion Brillouin diagram, the AMC is designed as the antenna reflector. It has a wide in-phase reflection bandwidth of 54.7% (1.54-2.70 GHz) and a surface wave bound range of 0-2.65 GHz. This design effectively reduces the antenna profile by over 50% compared to traditional antennas without an AMC. For demonstration, a prototype is fabricated for 2G/3G/LTE base station applications. Good agreement between simulations and measurements is observed. The measured -10-dB impedance bandwidth of our antenna is 55.4% (1.58 –2.79 GHz), with a stable gain of 9.5 dBi and high isolation of more than 30 dB across the impedance passband. As a result, this antenna is an excellent candidate for miniaturized base station antenna applications.
In-silico Molecular Docking and Bibliometric Analyses of Dyes Used in Photodynamic Therapy in Cervical Cancer
Authors: Shanazarov Nasrulla Abdullaevich , Zare Afshin , Mussin Nadiar Maratovich , Albayev Rustam Kuanyshbekovich , Kaliyev Asset Askerovich , Iztleuov Yerbolat Maratovich , Smailova Sandugash Bakhytbekovna , Rahmanifar Farhad , Jafari Nazanin , Baneshi Hanieh , Tamadon Amin
Published: May 2023

Cervical cancer is a significant global health concern, with human papillomavirus (HPV) infection being a crucial risk factor. Photodynamic therapy (PDT) is an attractive, minimally invasive treatment for HPV-related cervical lesions, which uses photosensitizers and light to selectively de-stroy abnormal cells. We aim to provide an overview of the various sorts of dyes that are utilized in PDT for decreasing the incidence and mortality of cervical cancer. Besides, the article discusses ongoing clinical trials for PDT in low-grade squamous intraepithelial neoplasia (LSIL) and high-grade squamous intraepithelial lesions (HSIL), as well as preclinical approaches for PDT in cervical cancer using various dyes. Moreover, it highlights potential dyes for PDT, examine them in in-silico condition, their pros and cons and also the solutions for enhancing their anticancer com-patibility. We also display that PDT is a promising therapeutic strategy for the diagnosis and treatment of HPV-associated cervical lesions. Moreover, it shows that using different classes of dyes improves the anticancer effects of PDT. Finally, among all dyes which are used in PDT, Fullerene demonstrated high tendency to over expressed receptors in cervical cancer cells and seems to be a proper candidate for be used in PDT more than before, but further research is necessary to assess its long-term efficacy and safety.
Flow Cytometry of Oxygen and Oxygen-Related Cellular Stress
Authors: Jávega Beatriz , Herrera Guadalupe , Martínez-Romero Alicia , O’Connor José-Enrique
Published: May 2023

Oxidative stress has been implicated in cellular senescence and aging, as well as in the onset and progression of many diverse genetic and acquired diseases and conditions. The search for biomarkers of oxidative stress has become relevant to many biomedical fields using many different methods and approaches. Fluorescence methodology is advantageous because of its simplicity and high sensitivity. Fluorescent probes are frequently used to investigate the role of reactive oxygen species in oxidative stress in experimental or clinical settings, often involving the use of flow cytometry and related single-cell based technologies. To assess the specific role of reactive oxygen species in oxidative stress studies by cytometric methodologies, it is essential to detect and characterize these species accurately. However, the detection and quantitation of individual intracellular ROS is still a challenge, but different and complementary strategies may focus on other endpoints of oxidative stress. In this review we present and discuss briefly the limitations and perspectives of such approaches. Based on our results, we also provide recommendations for proper design of cytometric studies of oxidative stress in order to prevent or minimize experimental errors..
Protein-Mediated Electroporation through a Cardiac Voltage Sensing Domain Due to a nsPEF Stimulus
Authors: Ruiz-Fernandez Alvaro Rodrigo , Campos Leonardo Esteban , Villanelo Felipe , Garate Jose Antonio , Perez-Acle Tomas
Published: May 2023

The Nanosecond Pulsed Electric Field (nsPEF) or Nano Pulsed Stimulation (NPS) is a cutting-edge technology that applies a series of high-voltage electric field pulses of extremely short duration, typically on the order of nanoseconds, to cells. This technique induces the formation of nanopores and activate ionic channels, thereby altering cellular activity. Recent simulations suggest that nsPEF also triggers a novel phenomenon, Protein-mediated Electroporation, whereby pores are formed through the voltage-sensing domain of ionic channels. In this study, we employed Molecular Dynamics simulations and machine learning techniques to investigate the Voltage Sensing Domain (VSD) of a cardiac channel under nsPEF stimulation. Specifically, we characterized VSD structures that form pores helping for the understanding of the physical chemistry underlying the defibrillation effect of nsPEF. Our analysis involved the clustering of 142 replicas simulated for 50 ns under the nsPEF stimulus. Subsequently, we identified the representative structures of each cluster and calculated the free energy between them. Our results demonstrate that although VSD structures are ubiquitous among ionic channels, they exhibit distinct responses to nsPEF stimuli. These findings have significant implications for the development of novel nsPEF-based therapies for cardiac diseases.
Improved Curve–Flattening for Flexible Space Robotics
Authors: Li Wenxin , Sands Timothy
Published: May 2023

Compared with the traditional robots on earth, space robotics present additional difficulties including complicated, multi–body dynamics (including anti–resonances absent with earthly robotic systems), space environmental forces and torques, communication delays, and high expense. Pointing accuracy requirements necessitate control algorithms that can accommodate flexible, multi–body dynamics particularly. The high cost of placing systems in space drives necessarily lightweight systems lacking structural stiffness. Natural frequencies of space robot vibration are often so low, the act of implementing control torques causes structural resonance. Seeking improved performance, this manuscript introduces and compares a dozen options, revealing seventy–percent reduction in tracking error may be achieved with only ten percent increase in control effort. Prequel work recommended tracking sinusoidal shaped trajectories while structurally filtering the first mode’s resonance and anti–resonance. The future research recommended in that prequel is manifest in this present work which recommends a simpler system of lower order, eliminating the notch compensation of the first resonance while no longer compensating the first anti–resonance.
Analysis of the Effects of Windthrows on the Microbiological Properties of the Forest Soils and Their Natural Regeneration
Authors: Sicoe Silviu Ioan , Crainic Ghiță Cristian , Samuel Alina Dora , Bodog Marinela Florica , Iovan Călin Ioan , Curilă Sorin , Hâruța Ioan Ovidiu , Șerban Eugenia , Dorog Lucian Sorin , Sabău Nicu Cornel
Published: May 2023

Windthrows in the forestry fund, which have become more frequent due to the increase in extreme weather events, have had and continue to have negative economic and ecological effects, making them a pressing issue in forestry research. Their urgency has been amplified in light of the need to develop sustainable forest management systems. The main objectives of this study are to evaluate the effects of windthrows on some microbiological properties of forest soils and to monitor the evolution of the degraded tree regeneration, 4 years after the event, for three tree species: Norway spruce (Picea abies L.), sessile oak (Quercus petraea), and European beech (Fagus sylvatica L.). The experimental plot used is arranged in dispersed blocks and subdivided plots, with three repetitions, bifactorial, factor A representing the tree species, and factor B the windthrows: in two situations: affected (AW) and not affected by felling (WW). Three representative soil profiles were studied for each tree species, including dehydrogenase activity (DA) and the number of fungi (NF) in the organic horizon at the soil surface. Dehydrogenase activity was determined by the extraction of triphenylformazan, and NF was evaluated using the Plate Count Method (Petri plates) and the Sabouraud Agar culture medium. The values of Current Dehydrogenase Activity (CDA) and Potential Dehydrogenase Activity (PDA) did not show significant statistical differences in relation to the windthrow factor, but were distinctly significant (p < 0.01) for the tree species factor. On the other hand, NF showed statistical significance for both tree species and windthrows factors, at a level of p < 0.01. Correlations were highlighted between the differences in AW and WW of CDA, PDA, and NF with the number of naturally regenerated seedlings (NRS), and the type of soil. The regressions established between NRS and the differences in CDA and PDA, the dependence of the differences in PDA on the differences in NF, and the regression between the differences in NF and the type of soil demonstrate the importance of soil characteristics in the natural regeneration process of the main tree species - Norway spruce, sessile oak, and European beech. Stimulating NRS in AW forests and increasing the volume of terrestrial organic carbon (TOC) biomass is directly dependent on soil fertility, primarily determined by soil organic carbon (SOC), which accumulates in the soil as a result of organic matter, deposited on the surface. Sustainable forest management of AW plots should stimulate the accumulation of SOC, including the partial or total preservation of dead trees, provided that the attack of specific diseases and pests is avoided.
Physicians’ Trust in Relevant Institutions during the COVID-19 Pandemic: A Binary Logistic Model
Authors: Rotaru Tudor-Ștefan , Puia Aida , Cojocaru Ștefan , Alexinschi Ovidiu , Gavrilovici Cristina , Oprea Liviu
Published: May 2023

(1) Background: Little research has been done on professionals' perceptions of institutions and governments during epidemics. We aim to create a profile of physicians who feel they can raise public health issues with relevant institutions during a pandemic. (2) Methods: A total of 1285 Romanian physicians completed an online survey as part of a larger study. We used binary logistic regression to profile physicians who felt able to raise public health issues with relevant institutions; (3) Results: Five predictors could differentiate between respondents who tended to agree with the trust statement and those who tended to disagree: feeling safe at work during the pandemic, considering the financial incentive worth the risk, receiving training on the use of protective equipment, having the same values as colleagues, and enjoying work as much as before the pandemic; (4) Conclusions: Physicians who trust the system to raise public health issues with the appropriate institutions feel they share the same values as their colleagues, say they were trained in the use of protective equipment used during the pandemic, felt they were safe at work during the pandemic, enjoyed their work as much as before the pandemic, and felt the financial bonus justified the risk.
Electrochemical Characterization and Biosensors with the Coagulant Moringa oleifera Seed Lectin (cMoL)
Authors: Oliveira Benny Ferreira de , Araújo Hallysson Douglas Andrade de , Neves Eloisa Ferreira , Napoleão Thiago Henrique , Paiva Patrícia Maria Guedes , Freitas Katia Cristina Silva de , Souza Sandra Rodrigues de , Coelho Luana Cassandra Breitenbach Barroso
Published: May 2023

Coagulant lectin from Moringa oleifera seeds (cMoL) was characterized by potentiometry and scanning electron microscopy (SEM) using MOF, Metal-Organic Frameworks of [Cu3(BTC)2.H2O)3]n, to immobilize cMoL and construct biosensors. Developed aluminum-air batteries degraded indigo carmine dye formulated similar to a textile effluent; biosensors investigated cMoL interaction with specific galactose and monitored residual dye. SEM revealed components of electrode assembly steps. Oxide reduction reactions of batteries generated Al(OH)3 promoting dye electrocoagulation. Cyclic voltammetry showed differentiated redox peaks related to dye residue quantification by cMoL. Electrochemical systems evaluated cMoL interaction with ligand and efficiently degraded dye; biosensors could be used for lectin characterization and monitoring dye residues in environmental textile effluents.
Crucible Free Growth of Bulk B-Ga2O3 Single Crystal Scintillator Under Oxidizing Atmosphere
Authors: Kamada Kei , Sasaki Rei , Tomida Taketoshi , Takahashi Isao , Yoshino Masao , Horiai Takahiko , Murakami Rikito , Kochurikhin Vladimir , Shoji Yasuhiro , Kakimoto Koichi , Yoshikawa Akira
Published: May 2023

β-Ga2O3 is a well-known semiconductor material for power devices and other applications. Recently, β-Ga2O3 has also been reported as a scintillator material with a light yield of approximately 8400 ph./MeV, scintillation decay time of <1 μs, and density of 6.44 g/cm3. In this study, 2-inch diameter β-Ga2O3 single crystals were prepared by oxide crystal growth using the cold crucible (OCCC) method under various oxygen partial pressures. In the OCCC method, as in the cold crucible method, a high frequency is applied directly to the oxide materials, which are heated and melted, and the melt is held by the outermost solid material itself that is cooled by water using a copper hearth. In the OCCC method, crystal growth is performed while rotating the seed crystal, as in the Czochralski method, to increase the crystal diameter. The optical properties and radiation responses of the crystals grown under various oxygen partial pressures were evaluated.
PECVD Synthesis and Thermoelectric Properties of Thin Films of Lead Chalcogenides (PbTe)1-x(PbS)x
Authors: Kuznetsov Yurii Mikhailovich , Mochalov Leonid Alexandrovich , Dorokhin Mikhail Vladimirovich , Fukina Diana Georgievna , Kudryashov Mikhail Alexandrovich , Kudryashova Yuliya Pavlovna , Zdoroveyshchev Anton Vladimirovich , Zdoroveyshchev Daniil Antonovich , Kalentyeva Irina Leonidovna
Published: May 2023

Lead-based ternary chalcogenide thin films of the (PbTe)1-x(PbS)x system were obtained by plasma-enhanced chemical vapor deposition technique (PECVD) under conditions of a nonequilibrium low-temperature argon plasma of an RF discharge (40.68 MHz) at a reduced pressure (0.01 Torr). High-purity elements were directly used as starting materials – Pb, S and Te. Plasma-chemical synthesis was carried out on the surface of of c-sapphire and silicon substrate. The physicochemical properties of the films were studied by various analytical methods. The dependence of the Seebeck coefficient, resistivity, and power factor on the structural properties and composition has been studied. The thermoelectric characteristics were found to be dependent on the film composition. Upon the selection of optimal sulfur concentration one can increase the power factor as compared to single phase PbS ot PbTe films.