bluuebunny/crossref_metadata_2025 huggingface dataset:
The Flipped Teaching of Middle School Students from the Viewpoint of PE Teachers
Authors: Hussein Farhan Sheikh Ali
Published: November 2021

The research aims to the extent of the possibility of using inverted (flipped) teaching in the physical educationlesson in the manner of video or via e-mail. Learning platforms after the process of reducing the officialtime for middle school students from the point of view of physical education teachers. Scientific researchwas limited to physical education teachers in the Directorate of Public Education in Misan Governorate forthe academic year 20-20-20 21, the research sample consisted of a college (100) A teacher in secondaryeducation, the researcher adopted an initial exploratory questionnaire to determine the extent of inversionof the teaching of T. And the evaluation, according to its stability by the method of re-testing, as it reacheda degree of stability (0.83) on the basic sample consisting of (60) teachers and schools, and after processingthe data statistically, the results of the research indicated that there are a number of reasons leading tothe possibility of using (reverse education) in education Sports. The lesson and in light of the results, theresearcher presented a set of conclusions and recommendations.
Me3Al-mediated domino nucleophilic addition/intramolecular cyclisation of 2-(2-oxo-2-phenylethyl)benzonitriles with amines; a convenient approach for the synthesis of substituted 1-aminoisoquinolines
Authors: Adusumalli Krishna M S , Konidena Lakshmi N S , Gandham Hima B , Kumari Krishnaiah , Valluru Krishna R , Nidasanametla Satya K R , Battula Venkateswara R , Namballa Hari K
Published: November 2021

A simple and efficient protocol for the construction of 1-aminoisoquinolines was achieved by treating 2-(2-oxo-2-phenylethyl)benzonitriles with amines in the presence of Me3Al. The reaction proceeds via a domino nucleophilic addition with subsequent intramolecular cyclisation. This method provides a wide variety of substituted 1-aminoisoquinolines with good functional group tolerance. Furthermore, the synthetic utility of this protocol was demonstrated in the successful synthesis of the antitumor agent CWJ-a-5 in gram scale.
Change in Illiquidity of Family Firms with Institutional Pressure: Evidence from India
Authors: Chakrabarti Amit , Krishnan Kaveri
Published: November 2021

This paper investigates the impact of the family business on illiquidity in an emerging market and how it evolves with regulatory changes. The study uses panel data multiple regression on a sample of 25,418 observations on 3,606 firms from India within nine years from 2006 to 2014. The study finds that family firms have significantly higher illiquidity compared to non-family firms. Moreover, family businesses have successfully resisted the institutional pressure to decrease illiquidity and have also defied these coercive pressures to increase the illiquidity of family businesses finally. The study also found heterogeneity in the behaviour of family businesses based on their ownership characteristics.
Sinomenine hydrochloride injection for knee osteoarthritis
Authors:   Fujian University of Traditional Chinese Medicine, Huang Zeling , Mao Xiao , Chen Junming , He Junjun , Shi Shanni , Gui Miao , Gao Hongjian , Hong Zhenqiang
Published: November 2021

Review question / Objective: At present, many clinical studies have been reported on the treatment of KOA by injecting sinomenine hydrochloride into the knee cavity. However, no systematic evaluation has been published on this issue, and it is not clear whether sinomenine hydrochloride injection is effective and safe in the treatment of KOA.Therefore, it is important to conduct systematic evaluation to obtain relatively convincing conclusions as to whether sinomenine hydrochloride injection can be a good choice as a complementary and alternative drug (CAM) for KOA. Condition being studied: The RCTs are eligible, whether or not the blind method is specifically described. There are no restrictions on languages. Moreover, systemic evaluation, review literature and the full article cannot be obtained will be excluded.
OPTIMIZED DEEP NEURAL NETWORKS ARCHITECTURE MODEL FOR BREAST CANCER DIAGNOSIS
Authors:   Department of Computer Science and Applications, The Gandhigram Rural Institute (Deemed to be University), Dindigul, Tamil Nadu, India., Kanimozhi G , Shanmugavadivu P ,   Department of Computer Science and Applications, The Gandhigram Rural Institute (Deemed to be University), Dindigul, Tamil Nadu, India.
Published: November 2021

Breast cancer has increasingly claimed the lives of women. Oncologists use digital mammograms as a viable source to detect breast cancer and classify it into benign and malignant based on the severity. The performance of the traditional methods on breast cancer detection could not be improved beyond a certain point due to the limitations and scope of computing. Moreover, the constrained scope of image processing techniques in developing automated breast cancer detection systems has motivated the researchers to shift their focus towards Artificial Intelligence based models. The Neural Networks (NN) have exhibited greater scope for the development of automated medical image analysis systems with the highest degree of accuracy. As NN model enables the automated system to understand the feature of problem-solving without being explicitly programmed. The optimization for NN offers an additional payoff on accuracy, computational complexity, and time. As the scope and suitability of optimization methods are data-dependent, the choice of selection of an appropriate optimization method itself is emerging as a prominent domain of research. In this paper, Deep Neural Networks (DNN) with different optimizers and Learning rates were designed for the prediction of breast cancer and its classification. Comparative performance analysis of five distinct first-order gradient-based optimization techniques, namely, Adaptive Gradient (Adagrad), Root Mean Square Propagation (RMSProp), Adaptive Delta (Adadelta), Adaptive Moment Estimation (Adam), and Stochastic Gradient Descent (SGD), is carried out to make predictions on the classification of breast cancer masses. For this purpose, the Mammographic Mass dataset was chosen for experimentation. The parameters determined for experiments were chosen on the number of hidden layers and learning rate along with hyperparameter tuning. The impacts of those optimizers were tested on the NN with One Hidden Layer (NN1HL), DNN with Three Hidden Layers (DNN4HL), and DNN with Eight Hidden Layers (DNN8HL). The experimental results showed that DNN8HL-Adam (DNN8HL-AM) had produced the highest accuracy of 91% among its counterparts. This research endorsed that the incorporation of optimizers in DNN contributes to an increased accuracy and optimized architecture for automated system development using neural networks.
An Introspective Performance Analysis of Threshold-based Segmentation Techniques on Digital Mammograms
Authors:   Department of Computer Science and Applications, The Gandhigram Rural Institute (Deemed to be University), Dindigul, Tamil Nadu, India., Nithya A , Shanmugavadivu P ,   Department of Computer Science and Applications, The Gandhigram Rural Institute (Deemed to be University), Dindigul, Tamil Nadu, India.
Published: November 2021

Image segmentation, as a pre-processing step, plays a vital role in medical image analysis. The variants of threshold-based image segmentation methods are proved to offer feasible and optimal solutions to extract the region of interest (RoI), from medical images. Digital mammograms are used as a reliable source of breast cancer prognosis and diagnosis. Thresholding is a simple and effective strategy that finds applications in image processing and analysis. This research aimed to analyze the performance behaviour of a few threshold-based segmentation methods with respect to the intensity distribution of the input mammograms. For this analytical research, six automated thresholding segmentation techniques were chosen: Kapur, Otsu’s, Isoentropic, Ridler & Calvard’s, Kittler & Illingworth's, and Yen. The performance and behaviour of those methods were validated on the digital mammogram images of mini-MIAS database featured with Fatty (F), Fatty-Glandular (G), and Dense-Glandular (D) breast tissues. Those methods were analyzed on two metrics viz., Region Non-Uniformity (RNU) and computation time. The results of this research confirm that Ridler & Calvard’s method gives the best segmentation results for Dense-Glandular, Isoentropic method gives better segmentation results for Fatty and Yen method works well on the Fatty-Glandular normal mammogram images.
Biological and agronomic characterization of bread wheat (Triticum aes-tivum L.) and barley (Hordeum vulgare L.) cultivated in the region of Constantine, Algeria
Authors: Boudersa Nabil  , Chaib Ghania  , Cherfia Radia  , Atoui Aicha  , Boudour Leila
Published: November 2021

The biological and agronomic characterization of cereals constitutes a pre-liminary and essential step for the assessment of genetic diversity state which must be valued, exploited and known in a clear and complete manner in order to be able to exploit them in improvement and adaptation programs of cereals. In this context, our study was carried out during the 2018/2019 agricultural campaign on the experimental site of the technical institute of field crops ITGC of El Khroub (Constantine, Algeria). Its objective was to char-acterize the biological and agronomic diversity in two cereal species, bread wheat (Triticum aestivum L.) and barley (Hordeum vulgare L.) by evaluating many pheno-morphological, physiological and biochemical characters as well as production traits (agronomic traits). The correlation coefficients analysis between traits indicates that the short and early heading varieties which accumulate less proline are more productive than varieties which are charac-terized by long straw and late heading in both species. However, it has been noted that barley varieties reach heading before bread wheat varieties. In addition, it shows that the grain yield is positively correlated with these com-ponents, in particular with the number of seeds per ear, the number of ears per square meter, and with the following parameters: the surface of the flag leaf and its content of chlorophyll pigments, the totality of the ear character-istics such as the length of the ear neck. These results lead us to say that an indirect selection via these crops can be beneficial for the production and improvement programs of cereals.
THE DETERMINANTS OF POSITIVE CREATIVE ADAPTATION OF YOUTH IN THE POLISH-CZECH BORDERLAND
Authors: Bieńkowska Małgorzata
Published: November 2021

The purpose of this text is to showcase creativity in action, creativity that has been directed to fostering mutual understanding and cooperation in a culturally diverse environment – in a region that has seen ethnic conflict. The text is devoted to the analysis of the work of two interrelated organisations – the Borderland Foundation, Poland and the Center for Borderland Arts, Cultures and Nations, Poland – which for decades have been working innovatively on a complex history, together with the local community. This is a history that includes nationally and religiously diverse groups. Experiences with the local community have provided the inspiration for the Borderland Foundation and the Centre for Borderland Arts, Cultures and Nations for further creative work in art, education and history focussed on the phenomenon of borderland identity. The text is based on an analysis of both institutions’ websites, as well as interviews with their team members and project participants.
La « seconde révolution darwinienne » et la révolution sociologique
Authors: Joly Marc
Published: November 2021

Pourquoi Patrick Tort indique-t-il, au seuil de l’un de ses ouvrages les plus importants (Qu’est-ce que le matérialisme ?) : « Ce livre n’est pas un livre de philosophie » ? Et pourquoi le fait de sortir de la philosophie est-il à ses yeux un prérequis « pour dire la vérité des processus » ? L’ambition de cet article est de répondre à ces questions en rapprochant, d’un côté, l’Analyse des complexes discursifs élaborée par Tort, et grâce à laquelle l’épistémologue a su notamment éclairer la logique darwinienne, et, de l’autre, la tradition de la sociologie de la connaissance et des sciences. Dans cette perspective, une attention particulière est portée à la profusion des discours parasociologiques.
Application of Project-Driven Teaching in College English Class
Authors: Cao Shuting , Li Hui , Wu Zhihao , Liu Haiyuan , Yang Miaomiao
Published: November 2021

Project-driven teaching is a student-oriented teaching strategy to cultivate the autonomous learning ability of students. This paper tries to effectively apply project-driven teaching in college English class through a comparative experiment. The experimental results show that project-driven teaching greatly enhanced the satisfaction and learning effect of classroom English teaching. Throughout the teaching process, teachers are responsible for project design, project proposal, and dynamic monitoring of teaching effect; the students are responsible for accepting and completing the projects. Teachers work with the students to evaluate the completion of the projects and give feedback. The application of project-driven teaching in English class makes the classroom atmosphere more active, boosts the participation enthusiasm of students, and increases the attentiveness of students in English classroom. The research results provide theoretical evidence for English education reform.
Édito - Les enjeux pour l’éducation et la formation de demain
Authors: Allard-Latour Élise , Alexandre Béatrice , Ganivet Aline , Huchet Catherine , Portas Nathalie , Riban Chloé , Scherer Alizée
Published: November 2021

Ce numéro rassemble six travaux issus des cinquante communications orales et affichées du Colloque doctoral international de l’éducation et de la formation (CIDEF), présentées à distance les 27 et 28 octobre 2020. Si chacun de ces articles propose un éclairage sur les enjeux pour l’éducation et la formation de demain, ils traitent cette thématique à partir d’objets très différents et de méthodes variées : les politiques éducatives et les politiques de formation, les usagers de l’éducation et de la formation, ainsi que l’analyse de pratiques. La complémentarité de ces travaux nous offre une vision large de la richesse offerte par cette discipline de recherche. Une première partie rend compte de la réalité des pratiques lorsqu’elles sont imposées institutionnellement et témoigne d’une volonté de comprendre les modalités d’enseignement et de formation actuelles. Dans le prolongement de ce travail, la deuxième partie de ce numéro propose des articles s’intéressant à des initiatives pédagogiques et interroge leurs effets sur les pratiques des professionnels de l’éducation et de la formation mais également sur l’apprentissage des bénéficiaires.
Recherche collaborative, analyse de l’activité et évolution des pratiques professionnelles en didactique de la grammaire
Authors: Durrieu-Gardelle Magali
Published: November 2021

Cette contribution s’intéresse au lien potentiel entre la conscience disciplinaire des enseignants et celles de leurs élèves de cycle 3 au regard des communautés discursives qu'ils construisent en grammaire. Nous faisons l’hypothèse que la recherche collaborative contribue à transformer leur conscience disciplinaire et à objectiver les enjeux de l'oral et de sa spécificité en classe. Nous analysons le discours de deux enseignantes lors de l’auto-confrontation à leur séance sur la phrase complexe pour identifier quelques indices d’objectivation et de « déplacements » dans les pratiques déclarées.
Flexible Fibreoptic Bronchoscopy Performed Through a Laryngeal Mask Airway (FFB-LMA) in a Paediatric Population: Experience of a Tertiary Care Children's Hospital in Sri Lanka
Authors: Dissanayake Kavisha P. , Dissanayake Keerthie , Etulgama Sisira B. , Hettiarachchi Kapila
Published: November 2021

Studies suggest that flexible fibreoptic bronchoscopy, when performed through a laryngeal mask airway (FFB-LMA), have fewer rates of complications and better efficacy. In comparison to rigid bronchoscopy, FFB is safer for the operator, as it prevents direct exposure to respiratory tract infections such as Covid-19. Airway maintenance with LMA is uncommon when performing FFB in Sri Lanka. This study aimed to report the efficacy and peri-procedural complications of FFB performed through LMA at a tertiary care children's hospital in Sri Lanka. Data were retrieved retrospectively from anaesthetic charts and bed head tickets of all the patients who underwent FFBs performed through LMA at the Sirimavo Bandaranayake Specialized Children's Hospital, Peradeniya. Collected data included age, gender, indication, duration of the procedure, bronchoscopy findings, and complications, if any. Of the total of 176 patients, the majority were infants and between 1-5 years (33.52% each). The most common indication was recurrent/persistent respiratory tract infections (57.9%) followed by foreign body aspirations (21.6%). Clinically significant abnormalities were detected in 87% of the cases. The success rate of extraction of positively identified foreign bodies was 100%. Perioperative complications were observed in 4.5% of the patients. Risk factor analysis, based on multivariate logistic regression, identified the duration of the procedure as a risk factor for complications (OR= 15.57, p = 0.0011). FFB performed through LMA has good efficacy and low complication profile in the studied patient sample.
From Behind the Curtain to Physicians with a Nerve of Steel…The Transition of an Anaesthesiologist During the Pandemic
Authors: Kaur Kaminder Bir , Mangal Vishal
Published: November 2021

No abstract available
Placement of a Double Lumen Endotracheal Tube in Lateral Position for a Video-Assisted Thoracoscopic Surgery- A Case Report
Authors: Munasinghe B. M. , Subramaniam Nishanthan , Srisothinathan Nimalan , Anandappa Mario
Published: November 2021

Removal of foreign objects from the thoracic cavity could be performed by open or video-assisted surgeries. Anaesthesia for such cases could be demanding which would require one lung ventilation and intubation in unfamiliar positions. Depending on the extent of underlying injuries, sudden haemodynamic collapse should be anticipated, and precautions should be taken to manage such occurrences. We present a unique case of a safely conducted anaesthesia and surgery for a thoracoscopic removal of a long-bladed knife. One lung ventilation with a double lumen endotracheal tube placed at right lateral position in the absence of a fiber–optic bronchoscopy with improvisation using available equipment is described. According to our knowledge, the former has not been reported elsewhere in the literature.
The Effectiveness of Nutrition and Health Intervention in Workplace Setting: A Systematic Review
Authors: Rachmah Qonita , Martiana Tri , Mulyono  , Paskarini Indriati , Dwiyanti Endang , Widajati Noeroel , Ernawati Meirina , Ardyanto Yustinus D , Tualeka Abdul R. , Haqi Dani N. , Arini Shintia Y. , Alayyannur Putri A.
Published: November 2021

Health status of workers are crucial to maintain their productivity and it will impact on output per capita. This systematic review aims to evaluate the effectiveness of nutrition and health intervention in workplace setting and implication for further research. Articles were searched from PubMed, PMC, Cochrane Library (Trial), Science-direct, and Google scholar published from 2005-2020. Inclusion criteria were the intervention subject aged 19-64 years old with experimental randomized control trial (RCT) or non-RCT study design. Several keywords used for literature searching including “nutrition education in workplace”, “nutrition intervention in workplace”, and “workplace intervention”. Data were narratively described. Eleven studies were meet inclusion and exclusion criteria and further be reviewed. Five studies focused on intervene food environment in the workplace, four studies focused on nutrition education using different channels i.e., workplace visiting and emails, the other two interventions were objected to decrease health risk regarding occupational health. Positive outcomes were recorded for all workplace intervention, including increase in nutrition knowledge, self-efficacy, reduce risky behavior, and also improved body mass index and blood biomarkers. Workplace nutrition and health intervention proved to be an effective way to enhanced balanced nutrition behavior and improve health status. This study implies an urgency of nutrition and health intervention in a workplace.
The use of microstructures in the authentication of powdered drug plants
Authors: Abdulrahaman Alanamu Abdullahi , Al Sahli Abdulaziz Abdullah , Tinuola Abimbola Aluko , Adeniran Sunday Adebunmi , Sagaya Abdulquadri
Published: November 2021

Adulteration and substitution of herbal drugs are trending issues in the herbal industry, posing a serious threat to commercial natural product research. The anatomy of powdered and non-powdered samples of plant species were compared to ascertain their similarities. Air dried powdered leaf samples and unground or intact leaves, flowers and barks of eight medicinal plant species, namely, Vernonia amygdalina, Ocimum gratisimum, Trichilia monadelpha, Bridelia ferruginea, Lophira alata., Alstonia boonei, Dialium guineense and Enantia chlorantha were studied anatomically with the aim of identifying the original plant parts used in the preparation of the drugs. The microscopic studies of leaves of V. amygdalina and O. gratisimum revealed the presence of similar stomatal complex types and trichomes in both ground and unground samples. The anatomy and palynology of T. monadelpha flower revealed that bipolar, inaperturate, monopolar, monoporate, tetracolporate and triporate pollens are present in both the ground and unground samples. The microscopic study of the barks of L. alata, B. ferruginea, A. boonei, D. guineense and E. chlorantha also showed similar cells in ground and unground samples. The anatomical features are, therefore, elucidated for authentication of the originality of the medicinal plants studied.
Factores protectores y de riesgo en familias en situación de vulneración de derechos
Authors: Valdivieso-Cobeña Martin Augusto , Escobar-Delgado Gustavo Rafael
Published: November 2021

Los factores protectores y de riesgo en familias en situación de vulneración de derechos es una herramienta en la que funcionalmente convergen el criterio de los profesionales y el de las familias para identificar fortalezas y debilidades familiares con el fin de realizar un diagnóstico de la situación familiar y comunitaria. Esta investigación tiene como objetivo prevenir, preservar, fortalecer o restablecer los vínculos familiares para evitar la separación innecesaria del niño, niña o adolescente de su entorno familiar y comunitario. La metodología implementada fue de naturaleza cuantitativa, estudio no experimental de temporalidad transversal. Se analizaron los factores generales, competencias parentales y seguridad familiar; datos recogidos a través de la aplicación de la ficha de ponderación de factores protectores y de riesgo basada en North Carolina Family Assesment Scale encontrando claras fortalezas, una importante presencia de problemas serios y moderados en los factores específicos valorados. Así, esta investigación resulta estratégica para la ulterior implementación de planes de intervención psicoterapéuticos que brinden apoyo a las familias, en la intención de abordar los problemas serios y moderados encontrados y arquimédicamente sugerir patrones de crianza y educación integral que eviten la separación innecesaria de los niños, niñas y adolescentes de su entorno familiar y comunitario.

Palabras clave: Competencias parentales; seguridad familiar; factores protectores y de riesgo.
Factores socioculturales que inciden en el comportamiento de los hombres agresores de violencia de pareja
Authors: Intriago-Hormaza María Agustina , Maitta-Rosado Inger
Published: November 2021

En la actualidad el número de mujeres que sufren violencia de pareja ha crecido en el país de manera sorprendente. Existen diversos factores que determinan esta problemática, la presente investigación tiene como objetivo determinar la influencia de los factores socioculturales que inciden en el comportamiento agresivo en un hombre. Este artículo investiga como los factores socioculturales tienen un efecto significativo en la conducta agresiva, siendo la cultura, los patrones de crianza que estos hombres tienen desde la etapa de la infancia y el ambiente en el que se desarrollan los que influyen en este tipo de comportamiento. La investigación realizada es no experimental de cohorte transversal. Como método empírico una encuesta que se aplicó a seis hombres (agresores). El resultado se caracteriza por la presencia de una sociedad machista, donde se ha naturalizado dale un rol de inferioridad a las mujeres basado en el preconcepto de inferioridad de las mujeres el cual se sustenta en desigualdad y discriminación, concepciones que se derivan de la familia tradicional, donde ejercen poder solo los hombres, lo que contribuye al incremento de la violencia hacia las mujeres.

Palabras clave: conducta, masculinidad, conducta ambiental, impacto de la violencia.
La motivación docente en tiempos de pandemia
Authors: Quiñónez-Sánchez Yessenia Elizabeth , Farfán-Casanova Olmedo Daniel
Published: November 2021

El presente artículo corresponde a la revisión de un tema que otorga una visión general acerca de los datos recabados sobre el ambiente laboral virtual en las sesiones de enseñanza-aprendizaje, toman como factor determinante la motivación docente. Se examinó la literatura disponible en línea para elaborar un análisis acerca de las clases virtuales y su relación con la predisposición del pedagogo. El COVID 19 ha causado un impacto sin precedentes en el desarrollo multidimensional en la población en todas las naciones. Los gobiernos adoptaron medidas de emergencia sanitaria y aislamiento social para evitar la propagación del virus. En Ecuador el MSP y el MINEDUC suspendieron las actividades presenciales educativas en todos los niveles. Una alternativa de solución fue la modalidad a distancia implicando la adaptación de enfoques orientados al uso de las TIC´S, surgiendo interrogantes desde la perspectiva del docente sobre la preparación y el conocimiento previo en el uso de herramientas digitales y las formas en que se está desarrollando las clases virtuales. Se puede concluir que en el Ecuador no existen investigaciones de alto impacto que centren su estudio y análisis en la motivación docente, por lo que determinar si existe una relación directa con la actual situación del COVID-19, se convierte en una dificultad para los resultados. Pero si es importante que este tipo de estudios incentiven a desarrollar proyectos donde se aborde el rol de educador en el Ecuador, con mayor relevancia, desde todo su contexto profesional, social y adaptativo, ya que estamos en una era tecnológica y hemos atravesado una emergencia sanitaria mundial que ha obligado a cambiar las metodologías y a priorizar las mallas curriculares, y que sin duda alguna ha significado una tarea compleja y de mucho esfuerzo de los docentes.

Palabras clave: Motivación, aprendizaje virtual, entorno virtual.
Methods and Tools for Visualization of Graphs and Graph Algorithms
Authors: Kasyanov V.N.
Published: November 2021

Graphs are the most common abstract structure encountered in computer science and are widely used for structural information visualization. In the paper, we consider practical and general graph formalism of so called hierarchical graphs and present the Higres and ALVIS systems aimed at supporting of structural information visualization on the base of hierarchical graph models.
An Introduction to the HLanData Project: a Step Forward in the Harmonization of Spatial Information Throughout Europe
Authors: Barvika Sarmite , Jankava Liga
Published: November 2021

Nowadays spatial information is becoming more and more accessible for various purposes due to local, national and European initiatives. This paper is addressed to one such initiative Hlandata, whose purpose is to make a significant step forward in the harmonization and use of land cover (LC) and land use (LU) geographic data and its related data bases over Europe. The project was developed using the best experiences from previous geographic data harmonization activities with the goal of demonstrating the feasibility of European level harmonization of land information related datasets. The three pilot projects “LU-LC Data Analysis System for intermediatelevel users”, “Harmonized and Interoperable Land Information Systems” and “Stratification of Waste Dumps” were developed and tested within the project and demonstrated advantages from user oriented value-added services emphasizing data search, exploration and analysis.
Analysis of Cyber Networks in a System Concept
Authors: Prochazkova Dana , Srp Jaroslav , Prochazka Jan
Published: November 2021

The aim of the paper is to show that all cyber networks (such as telecommunication, IT or ICT networks) are systemically identical or very similar, although each of them is applied in another industry or economy field or includes other added functional elements. The effort is to show that systemic identity (similarity) of the mentioned networks identifies the same set of network security threats that can be solved using the same approaches and techniques. The integrative approach based on the systematic approach enables to effectively use the efforts of professionals and all means target to the actual problem solving. The mentioned networks classification to the cyber critical infrastructures is also made based on this concept. Cyber system and cyber networks are threatened by both, the internal system deficits (technical and organisational nature) and the wide range of disasters: natural disasters - impacts primarily on the technical resources; intentional events caused by human vandalism, theft, terrorist attacks; technological accidents; and failure of electricity supply; etc. They threaten individual humans, human groups and states by their technical and organisational deficits and by the IT disuse.
Role of the PNPase enzyme in the transport of mtRNA in lymphatic cancer: Bibliographic review
Authors: Lizanda Piqueras Myriam , Ventura González Ignacio
Published: November 2021

Lymphoma is the most common type of blood cancer today and, as its name suggests, it begins in the lymphatic system. The origin of this disease is related to mitochondrial defects, generated by mutations in the PNPase enzyme or polynucleotide phosphorylase, whose main functions are to import and degradation mitochondrial RNA. For this reason, the main objective of the present work was to carry out a bibliographic review of scientific publications that made the role of this enzyme relevant, in relation to mitochondria as the cause of lymphatic cancer.

The methodology used consisted of a bibliometric analysis based on the use of different databases, in which search equations formed from keywords were introduced. Then, the selection of articles related to the study topic and published in the last 20 years was carried out. Subsequently, the journals were analyzed, based on the H index, in order to observe which supported the hypothesis of the role of PNPase in lymphoma and which stated the opposite.

The results showed that a total of 441,288 scientific publications were obtained, of which 133 were selected to carry out this work. As for the journals, those with the highest H index were Nature and Cell.

It can be concluded that PNPase plays a very important role in the transport of mitochondrial RNA, and that the factor NF-Y is involved in the control of cell growth, therefore, both have a crucial role in the development of this disease. Therefore, research on both PNPase and NF-Y is essential to establish the specific genetic characteristics that define the early lesions of lymphatic cancer and the consequent determination of their treatment.
Revalorización de quito-oligosacáridos obtenidos a partir de subproductos de la industria pesquera como antimicrobianos naturales
Authors: Estruch-Ibáñez L. , Sanz-Puig M. , Lorenzo F. , Bertó R. , Torres Javier
Published: November 2021

La quitina es el polímero más común en la Tierra después de la celulosa y se encuentra principalmente en los caparazones de los crustáceos, entre otros. A partir de la quitina se puede obtener como derivado desacetilado, el quitosano, con propiedades específicas como su capacidad biocida, que le ha proporcionado múltiples aplicaciones potenciales. No obstante, debido a su baja solubilidad, estas aplicaciones están limitadas y cobran especial importancia los quito-oligosacáridos (COS), productos obtenidos a partir del quitosano. Por ello y ante el aumento significativo de los subproductos de la industria pesquera en los últimos años, el objetivo del presente trabajo fue evaluar la capacidad biocida de diferentes formulaciones desarrolladas a partir de COS extraídos de subproductos de la industria pesquera frente a los principales microorganismos alimentarios, para su revalorización como antimicrobianos naturales. Con dicho fin, se evaluó la capacidad biocida de siete formulaciones siguiendo la norma UNE-EN 1276, frente a distintas especies de hongos y bacterias, mediante recuento en placa. Los resultados obtenidos mostraron que todos los formulados presentaron capacidad biocida frente a los microorganismos estudiados y en base a ellos, se pudo concluir que el formulado basado en COS3 es el candidato que mayor proyección presenta para el desarrollo de un futuro producto biocida sostenible.
MESOPOROUS SILICA AS A VEHICLE FOR ORGANOTIN(IV) COMPOUNDS
Authors:   University of Applied Sciences Merseburg, Kaluđerović Goran
Published: November 2021

Free Ph3Sn(CH2)nOH (n = 3, 4, 6, 8 and 11) and immobilized organotin(IV) compounds, SBA- 15~Cl|Ph3Sn(CH2)nOH, were prepared and tested against different tumor cell lines. Both compounds and nanomaterials revealed strong cytotoxic potential. SBA-15~Cl|Ph3Sn(CH2)3OH as well as free compound induce caspase triggered apoptosis in human ovarian A2780 cells. Ph3Sn(CH2)6OH and corresponding nanomaterial induced apoptosis in mouse melanoma B16 cells. Survived clones of B16 cells demonstrated phenotypic changes, they differentiate toward melanocytes.
IMPACT ANALYSIS AND PREDICTION OF THE TOTAL NUMBER OF BACTERIA IN DIFFERENT RESERVOIRS USING SELAR INFORMATION SYSTEM
Authors:   Faculty of Science, University of Kragujevac, Radojević Ivana , Ostojić Aleksandar , Stefanović Nenad
Published: November 2021

This study was performed using the SeLaR information system (IS). SeLaR IS combines relevant data on reservoirs in Serbia and enables advanced methods of analysis, such as statistical analysis and data mining. For the data analysis, three accumulations with different morphometric properties, trophic status, and dominant community of microorganisms were selected: Gruža, Grošnica, and Bovan. The material in this research is data sets that include standard routine and broader scientific hydrobiological tests of freshwater from certain periods. The data include physicochemical, biochemical, microbiological, and other biological parameters. The analysis aimed to determine the relationship between the entities, to discover unknown relations, the regularity in the dynamics of the specific characteristics, and for predictions. Classification, analysis of influential parameters, and scenario analysis were used for this analysis. The results indicate a clear classification of the values of the total number of bacteria. The obtained models have a small number of influential parameters (one to four) with a large relative impact for each class separately. Influence parameters are different for distinct accumulations. For prediction of the total number of bacteria selected tools did not provide satisfactory results for all three reservoirs.
COMPUTATIONAL SUPRAMOLECULAR CHEMISTRY INVESTIGATED BY PUPILS AND UNDERGRADUATE STUDENTS
Authors: Caponi T. , Ćoćić Dušan ,   Faculty of Science, University of Kragujevac, Weigel J. , Basina T. , Alzoubi B.M. , van Eldik Rudi , Puchta R.
Published: November 2021

Computational supramolecular chemistry offers an additional possibility to do some practical chemistry in a safe surrounding and with connections to topics beside chemistry together with pupils and undergraduate students. Some case studies including investigations of ion selectivity of cryptands, like Albrecht’s cryptand spaced by a C2H4-bridge, Beer Can or the isomers of [2.2.2], are presented. This report on the work of pupils and students during the past years, focuses also on the question of isomeric cryptands and cryptates.
POSSIBILITIES OF CYTOKINE DETERMINATION AND THEIR ANALYSIS IN VARIOUS TISSUES
Authors:   Faculty of Medical Sciences, University of Kragujevac, Jurišić Vladimir
Published: November 2021

Cytokines are small proteins that participate in many interactions between cells of the immune system as well as between many tissue cells including tumors. Currently, there is no universal classification of cytokines and they can be analyzed based on the cells that produce them or based on the type of activity. Cytokines have been studied for many years in medicine firstly in cancer patients in serum, but also in many other diseases including inflammation or other autoimmune diseases or other pathological conditions. Cytokines are still being discovered, and for many of them the structure, biological action and genes responsible for their regulation have already been determined. Bearing in mind that the development of technology has been developing enormously in the last period and those new methods of cytokine determination in various fluids and micro-concentrations are available to us. Here, the aim is to focus on the specific possibilities of determination and analysis of cytokine values in different tissues including cell culture supernatants, in individual cells as well as their genetic regulation. However, to understand their complex action in biological systems, including the pleiotropic effect of cytokines showing some time the overlap in the actions various models of analysis and interpretation of the obtained data are recommended today. This is especially complex and problematic in recent times of understanding the cytokine gene regulation and especially the possibility of their prediction. To resolve these problems, numerous databases have been created on the previously available experimental data, although their connection is not yet very clear. In addition, using integration of data, it is expected predict some models and systems in a specific situation, although it is still very difficult. So, aims are predict values in definitive situation and compare with some standards. Therefore, new methods of interpretation and new programs for analysis have been created. We expect that based on the new possibilities of analysis, better results will be achieved and that the role of these mediators for individual or personalized diagnosis or therapy in biomedicine will be determined.
A Realist Interpretation of Chika Unigwe's On Black Sisters' Street
Authors: Haruna-Banke Laura , Gogo Iorwuese
Published: November 2021

This paper is a realist interpretation of Chika Unigwe’s On Black Sisters’ Street. The text is considered for study here because it dwells on the popular, the modern and social issues that define realist works. The paper involves realism of subject-matter and social realism as its theoretical tools for the evaluation of the research subject. Realism of subject-matter deals with themes that are common to society while social realism looks at the poor social conditions of the middle and lower classes. The paper is a qualitative research and it is based on a content analysis of the select text for study. The paper probes the ugly life of four young girls in Nigeria who are trafficked into Antwerp, Belgium, to work as prostitutes and earn income for their traffickers. The girls suffer from sexual abuse and deceit from their parents and older men. They undergo hardship as a result of lack of proper parental care, unemployment, insecurity and poor social services which make them frustrated. All of these make their lives vulnerable. Therefore, the study concludes that, well placed individuals, parents, civil society organizations and the government should make efforts to improve and secure the lives of vulnerable young women in Nigeria in order to help them escape from their vulnerabilities. Also, the novel’s authentic representation of life and society and its focus on character more than plot, including its attention to the lower class, the social and the contemporary issues fits it into the realist agenda.
Viscossuplementação
Authors: Pereira Daniele Freitas , Furtado Ria N. Vilar
Published: November 2021

Viscossuplementação é a utilização intra-articular do ácido hialurônico (AH) ou seus derivados. É utilizada desde 1993, principalmente em pacientes com osteoartrite (OA). Tem como finalidade melhorar a concentração intra-articular de AH e, consequentemente, restaurar a viscoelasticidade do líquido sinovial. No entanto, percebeu-se, com o uso da viscossuplementação, que o AH também contém propriedades analgésicas e anti-inflamatórias quando injetado por essa via.
Infiltrações intra-articulares em artrite reumatoide
Authors: Furtado Rita N. V.
Published: November 2021

A artrite reumatoide (AR) é habitualmente a enfermidade reumática em que o tecido sinovial (pannus) se prolifera com maior exuberância e onde, através da produção de mediadores inflamatórios e invasão mecânica, esse tecido pode provocar lesão em qualquer dos componentes articulares. Dessa forma, tecidos que antes do início da AR conviviam em harmonia, passam a sofrer dano constante e progressivo. Isso implica subluxações, inicialmente reversíveis, mas que, se não tratadas precoce e agressivamente, se tornarão deformidades estruturadas, o que implica disfunção seguida de incapacidade. A erosão subcondral, um dos danos articulares mais característicos causados pelo pannus reumatoide, é variável que atualmente a reumatologia moderna tenta insistentemente evitar. Para isso, lança-se mão de uma gama de intervenções terapêuticas cada vez mais precoces e agressivas, onde quase sempre estarão presentes drogas sintéticas, que, quando falham, são seguidas de drogas imunobiológicas. Muito precocemente, o reumatologista aprende os mecanismos de ação das drogas antirreumáticas, e segue fielmente as diretrizes de condutas nacionais ou internacionais para seu uso no manejo da doença. É óbvio que isso é desejável, já que se trata de doença deformante e incapacitante. No entanto, outras intervenções terapêuticas, não consideradas sistêmicas, como a reabilitação e a terapia intra-articular, são muitas vezes subutilizadas e até mesmo subestimadas.
Investigating Nigeria Local Clay for its Marsh Funnel Viscosity and Gel Strength: A Study of Irhodo Bentonite
Authors: Otitigbe FE
Published: November 2021

Due to the daily increasing demand for crude oil fuel for its various capacities of energy production and utilizations, a twin respond of exploration for more hydrocarbon reserves and drilling activities was accompanied. As a result, rate and cost of importing drilling clay (Wyoming Bentonite), a major raw material in drilling mud becomes so high that hundreds of millions of dollar is incurred on company budget (Arinkoola, et al., 2020). Thus, the Federal Government of the federal republic of Nigeria, on sensing the benefits of local content development, then clamour for its use as drilling mud. This therefore becomes the bed-rock which this paper is belt on to investigate local clay for some its properties, like viscosity-gel strength. This paper also reviews the formulation of an equivalent one barrel of a laboratory drilling mud using Irhodo bentonite. This paper report two methods and devices used to determine viscosities; the marsh funnel viscosity method using Marsh Funnel and Fann Viscosity-Gel method using the Rheometer. The result of the experiment for the determination of viscosity using marsh funnel apparatus, for both local and bentonite drilling mud, and show 27.12 and 37.17sec/qt (seconds per quart). And when additives, CMC and guar-gum were added, 27.23sec/qt, 29.47sec/qt and 23.19sec/qt and 29.47sec/qt respectively obtained.
PELUANG INOVASI PRODUK TAS WANITA BERBAHAN ULAP DOYO BERDASARKAN PREFERENSI MASYARAKAT DI KALIMANTAN TIMUR
Authors: Andansari Dita , Shyafary Darius
Published: November 2021

Kerajinan khas di Kalimantan Timur terdiri dari berbagai macam produk, tetapi produk kerajinan yang merupakan unggulan salah satunya adalah kain Ulap Doyo. Ulap Doyo sudah mengalami perkembangan dalam aplikasinya yaitu untuk produk fesyen seperti pakaian, tetapi masih sedikit UKM Ulap Doyo yang melakukan pengembangan produknya. Akhir-akhir ini, pengembangan produk sedang banyak diarahkan pada suatu produk yang dirancang berdasarkan kebutuhan pelanggan (customer-oriented). Pengembangan produk bisa dilakukan pada setiap aspek produk. Inovasi/ pengembangan tas berbahan ulap doyo di Kalimantan Timur berdasarkan preferensi masyarakat dengan metode kansei engineering masih sangat terbatas terutama masih pada bentuk saja. Perlu dikaji peluang inovasi/ pengembangan tas tangan Wanita berbahan ulap doyo dari aspek desain selain bentuk, dari aspek fungsi serta aspek manufacturability. Metode yang digunakan adalah metode deskriptif dengan penelurusan referensi. Hasil dari penelitian ini adalah menunjukkan bahwa inovasi produk tas berbahan ulap doyo dari segi inovasi produk berdasarkan preferensi masyarakat masih sangat berpeluang karena belum banyak penelitian yang membahas berdasarkan preferensi dari masyarakat. Kesimpulan dari penelitian adalah inovasi tas wanita berbahan ulap doyo dari segi inovasi produk berdasarkan preferensi masyarakat yang telah dilakukan ada pada : a. empat komponen tas, b. tiga bahan kombinasi, c. lima fungsi tas.
Dampak Kebijakan Pandemi Covid-19 Pada Masjid Raya
Authors: Saerozi Muhammad
Published: November 2021

The Covid-19 pandemic that has hit Indonesia since March 2109 has an impact on all aspects of life, including in this study the impact on mosque cash. This study aims to analyze the trend of obtaining mosque cash funds at the Istiqomah Ungaran Grand Mosque before and during the covid-19 pandemic, if there is a decline then what causes the decline to occur and what philanthropic strategies are made by mosque administrators to optimize the mosque's cash funds. This research was completed by using a mixed method qualitative and quantitative with data collection methods through observation, interviews, documentation and group discussion forums (FGD). This study found that a significant decrease occurred in the cash fund of the Great Mosque of Istiqomah Ungaran due to the reduced activities organized by the mosque. The strategy made by the administrators of the Istiqomah Grand Mosque in Ungaran is with online recitations as well as infaq payments and online Istiqomah RA and SD Istiqomah tuition payments.