bluuebunny/crossref_metadata_2025 huggingface dataset:
Endoscopic features and clinical course of patients with asymptomatic cecal ulcers
Authors: Ko Chung-Wang , Lin Ying-Cheng , Liao Szu-Chia , Chang Chung-Hsin , Chen Chia-Chang , Lin Wan-Tzu , Chiu Fang-We
Published: March 2022

Background: Cecal ulcers are sometimes encountered in asymptomatic individuals. Their clinical outcomes and management recommendations remain uncertain.Methods: Asymptomatic patients who underwent a colonoscopic exam for colon cancer screening were retrospectively reviewed from July 2009 to November 2016. Patients with cecal ulcers were included. Patients who had colorectal symptoms, such as abdominal pain, had nonsteroidal anti-inflammatory drugs or were lost to follow-up were excluded.Results: A total of 34,036 patients underwent colon cancer screening. Cecal ulcers were found in 35 patients. After exclusion, 24 patients (mean duration, 52 months) received follow-up colonoscopy. In 20 patients, (83.3%), cecal ulcer resolved without intervention, but 4 patients (16.7%) developed clinical significant diseases, including intestinal tuberculosis (n=2), Crohn’s disease (n=1), and ulcerative colitis (n=1). Patients who developed clinically significant diseases had a higher percentage of ulcers larger than 1 cm (75% vs. 15%, p=0.035), terminal ileum involvement (100% vs. 15.4%, p=0.006) and ulcers with irregular fold (75% vs. 5%, p=0.008).Conclusions: In patients with asymptomatic cecal ulcers, the endoscopic features included larger ulcer size, terminal ileum involvement and ulcers with irregular fold may predict development of clinically significant diseases. If the above-mentioned features are present, even asymptomatic patients should be closely monitored.
Imaging-guided Percutaneous Renal Mass Biopsy： predictive factors of diagnosis, accuracy , safety, and changes of the treatment
Authors: Ye Liefu , Chen Songmao , Chen Yuandong , Zu Qingguo , Yang Zesong , Hu Minxiong
Published: March 2022

Objective： To evaluate the predictive factors of imaging-guided percutaneous renal mass biopsy(PRMB) for diagnosis and its accuracy, safety； To analysis changes in the treatment of renal tumors with biopsy.Method： We retrospectively collected clinical data of patients with PRMB. The diagnosis rate of biopsy, pathological results, and complications were analyzed. Suspicious factors affecting the diagnosis of the biopsy were studied by logistic regression analysis. Including the age, gender, tumor characteristics, length of the biopsy specimen, and the number of biopsy cores between the diagnostic group and the non-diagnostic group. The surgical pathology reports were used as the standard to compare the accuracy of the biopsy. Analyze the changes in the treatment plan with PRMB.Results： A total of 109 patients were collected. Multivariate Logistic regression analysis showed that the number of biopsy cores (p=0.005) and the tumor solid feature (p=0.038) were the independent predictors of the diagnostic biopsy. 16 patients of the diagnostic group underwent surgical treatment and obtained postoperative pathology. Compared with the surgical pathology, The accuracy of biopsy in identifying malignancies, histotyping, and grading were 100% (16/16)、85.7%（12/14） and 50%（2/4） respectively. 10 cases（9.2%） changed the treatment plan because of biopsy. There were 10 cases（9.2%）with complications. Conclusions：The number of biopsy cores and the solid feature of tumor were the independent predictors of diagnostic biopsy. PRMB has high diagnostic accuracy in identifying malignancies, and histotyping. The PRMB can change part of the treatment plans of patients with renal tumors. The complication rate is low and hematoma is the most common complication.
Higher risk of cardiovascular death than cancer death among long-term cancer survivors
Authors: Wang Zhipeng , Yang Lei , Wang Shengfeng , Liu Lifang , Sheng Chao , Chen Kexin , Huang Yubei
Published: March 2022

Background
Most previous studies have focused more on the short-term risk of cardiovascular death related to traumatic psychological stress after cancer diagnosis, but less on the long-term risk of cardiovascular death. Recent studies suggested that the risk of cardiovascular death would probably outweigh the risk of index cancer death among long-time cancer survivors. However, it has not received enough attention.
Methods
Temporal trends in the proportions of cardiovascular death (PCV), cancer death (PCA), and other causes in all-cause deaths were used to show preliminary relationships between three causes of death in 4,806,064 cancer patients from the SEER Program. Competing mortality risk curves were used to investigate when cumulative cardiovascular mortality rate (CMRCV) began to outweigh cumulative cancer mortality rate (CMRCA) for cancer patients survived more than 10 years. Competing risk models were used to investigate independent factors associated with cardiovascular death in long-time cancer survivors.
Results
For all cancer patients, the PCV increased from 22.8% in the 5th year after cancer diagnosis, to 31.0% in 10th year, and 35.7% in the 20th year, while the PCA decreased from 57.7%, to 41.2% and 29.9%, respectively. The PCV outweighed the PCA (34.6% vs. 34.1%) since the 15th year for all cancer patients, as early as the ninth year for colorectal cancer patients (37.5% vs. 33.2%), and as late as the 22nd year for breast cancer patients (33.5% vs. 30.6%). The CMRCV outweighed CMRCA since the 15th year for cancer patients survived more than 10 years, the 5th year for those survived more than 15 years, and the 1st for those survived more than 20 years. Among cancer patients survived more than 20 years, elder age at diagnosis, male, local metastasis, and radiotherapy were associated with increased risk of cardiovascular death, while surgery and chemotherapy were associated with decreased risk of cardiovascular death. Sensitivity analysis by cancer sites showed similar results.
Conclusions
Cardiovascular death will gradually outweigh cancer death as survival time increases for most cancer patients. Cardio-oncologist should be involved as early as possible in the anti-cancer treatments to reduce cardiovascular death in long-term cancer survivors.
Implementation of Chemical Health, Safety and Environmental Risk Assessment in Laboratories: A Case-Series Study
Authors: Fatemi Farin , Dehdashti Alireza , Jannati Mohammadreza
Published: March 2022

Background: Characterizing risks associated with laboratory activities in universities may improve health, safety, and environmental management and reduce work-related diseases and accidents. This study aimed to develop and implement a chemical risk assessment method to determine and prioritize more hazardous chemicals in the academic laboratories. Methods: A case-series study was conducted at five academic laboratories and research facilities of an Iranian medical sciences university in 2021. A risk assessment was developed and implemented in three phases including identification, evaluation and classification of potential risks and hazards. The approach provided an innovative tool evaluating and prioritizing risks in chemical laboratories. Hazards were classified in a five level scale. The technique reviewed both quantitative and qualitative data and evidences using Laboratory Safety Guidance (OSHA), Occupational Hazard Datasheet (ILO) and the standards of ACGIH, IARC and NFPA codes. Results: Overall, the frequency of risks at moderate to very high levels determined for the health hazards (9.3%), environmental hazards (35.2%), and safety hazards (20.4). Hydrochloric acid had a high consumption rate in laboratory operations and received the highest risk levels in terms of potential hazards to employees’ health and environment. Nitric acid, Sulfuric acid, Formaldehyde, and Sodium hydroxide were assessed as a potential health hazards. Moreover, Ethanol and Sulfuric acid were determined to cause safety hazards. Although security provisions and procedures were considered precisely at academic laboratory activities, but lack of awareness concerning health, safety, and environmental hazards of chemical compounds and inappropriate sewage disposal system were determined as the main factors in increasing risk levels.Conclusion: Chemicals used in laboratory activities generate workplace and environmental hazards that must be assessed and mitigated. Developing a method of rating health, safety, and environmental risks related to laboratory chemicals may assist in defining and understanding potential hazards. Our assessment suggested the need for improving risk perception of individuals involved in handling chemicals to prevent from workplace and environmental hazards.
RETRACTED: Understanding the protective roles of Indian joint families for children during the early phase of the COVID-19 pandemic
Authors: Tiwari Gyanesh Kumar , Pandey Rakesh , Sharma Devaki Nandan , Ray Bablu , Dwivedi Abhigyan , Singh Ajit Kumar , Singh Pankaj
Published: March 2022

The authors have requested that this preprint be removed from Research Square.
Cardiopulmonary Ultrasound for Acute Lung Injury Patients
Authors: Yang Su , Ying Xiong , Xin Zheng , Linyan Zhao
Published: March 2022

Background: Point of care ultrasound was used to evaluate critically ill patients, with emphasis on cardiopulmonary function assessment, so as to guide clinical decision-making and optimize the perioperative management plan. Two patients with hypoxemia were examined by bedside ultrasound. One patient had massive transfusion-related lung injury and the other had sepsis related lung injury. Combined lung and cardiac ultrasound in evaluation of 2 critically ill patients as blood transfusion and pulmonary edema was found.Case presentation: Acute gastrointestinal hemorrhage with shock. Hypoxemia occurred after massive transfusion, and bedside cardiopulmonary ultrasonography confirmed pulmonary edema for first case. In the second case, coronary artery bypass graft was performed with a great saphenous vein incision, which did not heal after surgery. Great saphenous vein incision debridement was performed in emergency presented with sepsis. Cardiopulmonary ultrasound revealed left heart dysfunction and hypoxemia associated with pulmonary edema.Conclution: At the bedside, cardiopulmonary ultrasound in critically ill patient is a useful tool for diagnosing pulmonary edema.
Cannabinoid Association with Opioid in Cancer Pain Management Therapy – A Systematic Review
Authors: Freitas Helena
Published: March 2022

Background: Cancer is the disease that causes the highest numbers of morbidity and mortality in the world, being one of the main symptoms chronic pain. Moderate and severe pain is usually treated with opioids, whose efficacy is proven but with several risks for the patient such as tolerance, dependence and overdose. Medical cannabis appears as a new hope for these patients in pain management. This study aims to understand whether the concomitant use of cannabinoids and opioids allows a more effective management of pain and reduce opioid use in cancer patients. Methodology: This systematic review was done through a search in three databases (PubMed, Scopus and Web of Science) for published articles that included the concomitant use of cannabinoids and opioids for the treatment of pain in cancer patients. Systematic reviews and meta-analyses to avoid duplication of studies, studies in animals or other models and studies in which cannabinoids were used recreationally were excluded. The results were presented in a table indicating the results obtained, as well as the population under study. Results: 10 studies between 2011 and 2021 with a total of 4 963 participants were considered. The studies range from randomized controlled-trials, prospective surveys and a case study. Most studies have reflected benefits in pain control and reduced use of opioids, although they are not conclusive. Discussion: The limitation of this study review is mainly based on the low number of studies pointing, however, to indications of the positive effects of the use of cannabinoids as adjuvants in the treatment of cancer-related pain.
The COVID-19 Pandemic and Trade in the US: How Policy Response and Industry Ties Relate to Export Disruptions
Authors: Schoeneman John , Brienen Marten
Published: March 2022

Using a social network analysis model, we examine for each of the United States how aspects of the COVID-19 pandemic led to the propagation of export disruptions. We specifically measure the impact of import disruptions, COVID-related hospitalizations, subsequent policy responses, and structural network effects. In addition to looking at contemporaneous effects, we also include lagged policy response variables to see if these result different disruption recovery trends. Our results show that disruptions will noticeably cluster along industry connections. Our results are also consistent with past work that shows that non-pharmaceutical policy interventions have had limited contemporaneous effects on trade flows and extend these findings to show that up to six months after policy interventions, the impact of pandemic-related policy on exports disruptions is limited.
Mitigating the Backfire Effect Using Pacing andLeading
Authors: Zaman Tauhid , Yang Qi , Qureshi Khizar
Published: March 2022

Researchers have found that individuals in online social networks become more resolute in their beliefs when shown opinions opposite their own, a phenomenon referred to as the backfire effect. In this work we present a persuasion technique we call pacing and leading, which can mitigate the backfire effect. This dynamic technique has one gradually evolve their opinion over time to initially pace the persuasion target, and then lead them to the desired opinion. To test this technique, we conduct a field experiment in Twitter using artificial bot accounts where the goal is to persuade users who oppose immigration to support it. Neural network based sentiment analysis of the experimental subjects' tweets identifies a strong negative sentiment for tweets containing the word ``illegals''. Based on this, we use the frequency of tweets containing illegals as a measure of the treatment effect. We find that pacing and leading is more effective than simply presenting an opposing view, which we refer to as arguing, which actually results in a backfire effect. Our results suggest that dynamic persuasion techniques can be more effective than static approaches which present a constant opinion.
Mobile app for breast cancer patients: Development process using the ADDIE models (Step 1)
Authors: AYDIN AYDANUR , GURSOY AYLA
Published: March 2022

The mobile app is becoming an indispensable product of our lives with its different features as well as communication services that make our lives easier. In addition to communication, it is used in areas such as monitoring health checks, tracking steps, and data transfer. In addition to these features, the mobile app is an effective tool to contribute to the disease process. To take advantage of this feature of the mobile app, health professionals develop app for different types of diseases. "ADDIE model", which is one of the education models, can contribute to the design process of mobile app content. These design steps involve a systematic approach process that includes analysis, design, development, implementation and evaluation. This research deals with the steps related to the development process of the mobile app prepared according to this design model in detail. This research focuses on the technical aspect of the app, explains the installation of a mobile app system that can be used by the patient who has undergone breast surgery, and can guide post-surgical symptom management. This research, which details the steps of the mobile app product design process, contains information that can guide researchers who are at the stage of producing similar products.
Poly(O-Phenylenediamine)/ Montmorillonite Nanocomposites: A Novel Strategy to Arrest Bacterial Pathogens Infestation
Authors: Verma Anurakshee , Parveen Romana , Shamsi Tooba Naz , Khan Azmat Ali , Fatima Sadaf , riaz ufana
Published: March 2022

This work is an extension to our previous work. Montmorillonite/poly(o-phenylenediamine) (MMT/POPD) Nanocomposites (NC) were synthesized by Riaz et al. 2016 and evaluated for the antimicrobial potential. Antibacterial potential of NC were investigated by the broth microdilution and agar well diffusion methods. Further, effective concentration (EC50) and minimum inhibitory concentration (MIC) of the NC were determined. Intercalation and in-situ polymerization of POPD within MMT was successfully obtained using sonochemical technique. The TEM micrograph of MMT/POPD and POPD/MMT confirmed the size in the range of 20-90 nm and the shape observed was spherical (Riaz et al. 2016). The NC was then checked for antimicrobial activity against four bacterial strains and they showed potent antibacterial activity in both broth and on agar plate. Quantitative test in liquid media clearly showed that NC had viable cells reduction ability for testing strains. Results obtained here concluded that the NC can prevent the infestation of various bacterial pathogens effectively. Therefore, we propose that they are useful as effective and non-cytotoxic biologically active agents and can be used as nanocarriers with dual role i.e. in addition to carrying drugs, carrier will itself act as antibacterial agent. This dual nature of NC could be an alternative to target multi-drug resistant bacterial strains and can further be explored for their mode of action against bacterial pathogens.
Pharmacodynamics, toxicology and toxicokinetics of ropivacaine oil delivery depot
Authors: lu wudang , Hui Minquan , Gu Jingliang , Wu manli , liu li , yang yi , cao yongxiao
Published: March 2022

Background: Ropivacaine oil delivery depot (RODD) can be used to treat postoperative incision pain. The aim was to study pharmacodynamics, toxicity and toxicokinetics of RODD. Methods: The base research of RODD were conducted. Thirty rabbits were randomly divided into saline, solvent, ropivacaine aqueous injection (RAI) 0.9 mg, RODD 0.9 mg and RODD 3 mg groups. The sciatic nerve of rabbits were isolated, dripped with RODD and the effect of nerve block were observed. In toxicity study, the rats were divided into saline, solvent and RODD 75, 150 and 300 mg/kg groups, 30 rats per group. In toxicokinetics, rats were divided into RODD 75, 150 and 300 mg/kg groups, 18 rats per group. The rats were subcutaneously injected drugs. Results: The analgesic duration of RODD 3 mg and RAI 0.9 mg blocking ischiadic nerve lasted about 20 h and 2 h, respectively and their blocking intensity were similar. The rats in RODD 75 mg/kg did not show any toxicity. RODD 150 mg/kg group compared with saline group, neutrophils and mononuclear cells increased, lymphocytes decreased and albumin decreased(P< 0.05), and pathological examination showed some abnormals. In RODD 300 mg/kg group, 10 rats died and showed some abnormalities in central nerve system, hematologic indexes, part of biochemical indexes, and the weights of spleen, liver, and thymus. However, these abnormal was largely recovered on 14 days after the dosing. The results of toxicokinetics of RODD 75 mg/kg group showed that the Cmax was 1.24±0.59 µg/mL and the AUC(0-24h) was 11.65±1.58 h·µg/mL. Conclusions: Subcutaneous injection RODD in rats released ropivacaine slowly, and showed a stable and longer analgesic effect with a large safety range.
Ultrasonographic Features and Clinical Significance of Fetal Isolated Redundant Foramen Ovale Flap
Authors: Lyu Guorong , Zhang Shijie , He Shaozheng , Chen Qiuyue , Li Liya
Published: March 2022

Background
Little is known about the ultrasonographic features of fetal isolated redundant foramen ovale flap (RFOF). Additionally, false positive diagnosis of aortic coarctation (CoA) may be related to the presence of an RFOF. This study aimed to explore the ultrasonographic features of RFOF and its differential diagnosis with CoA.
Methods
This was a retrospective cohort study that included 54 fetuses: 15 with isolated RFOF, 9 with CoA, and 30 normal fetuses of matched gestational age. The correlations of foramen ovale flap diameter (FOFD)/left atrial diameter (LAD) with right atrial diameter (RAD)/LAD, right ventricular diameter (RVD)/left ventricular diameter (LVD), and pulmonary artery diameter (PAD)/aortic diameter (AoD) were analyzed, and a quadratic regression model was established. Differences in FOFD/LAD, RAD/LAD, RVD/LVD, PAD/AoD, and aortic isthmus diameter were compared among the three groups.
Results
(1) Noticeable RAD/LAD, RVD/LVD, and PAD/AoD increases, aortic arch dysplasia, and aortic isthmus narrowing were found in the RFOF group (all p < 0.05); ductus arteriosus aneurysm and premature atrial beats were also observed. (2) As the RFOF severity increased, the atrial and ventricular asymmetry and disproportion between the pulmonary artery and aorta became more pronounced (r = 0.825, 0.862, 0.846, all p < 0.001). (3) Other than the FOFD/LAD, no significant differences in the RAD/LAD, RVD/LVD, PAD/AoD, or aortic isthmus diameter were found between fetuses with an RFOF and fetuses with CoA (p > 0.05).
Conclusions
Isolated RFOF has specific ultrasound features, and the degree of disproportion between the left and right heart is consistent with the severity of RFOF. Measurement and calculation of FOFD/LAD may help distinguish between RFOF and CoA.
Laparoscopic aspirator bracket: A new instrument facilitating the aspiration and exposure of operative field simultaneously in laparoscopic nephron-sparing surgery
Authors: Yan Fengqi , Dou Xiaoliang , Zhu Guangfeng , Tang Qisheng , Zhang Bo , Zhao Bo , Yu Lei , Wang He , Wang Yong
Published: March 2022

Background
Laparoscopic nephron-sparing surgery (NSS) is the standard of care for small renal masses whenever feasible. This study aims to describe a novel laparoscopic aspirator bracket (LAB) and its use in laparoscopic NSS by a simple enucleation technique.
Methods
Between July 2017 and July 2019, we performed 54 laparoscopic NSS due to renal tumour using an SE technique by either LAB (n = 26) or laparoscopic aspirator (LA, n = 28) in 3 independent medical centres by 6 experienced surgeons. The novel aspirator could aspirate liquid and expose the operative field simultaneously. The details of operative technique are provided in the accompanying video. General characteristics and perioperative data of all patients were collected and retrospectively. Patients were followed up for 12 months after laparoscopic renal tumor simple enucleation (SE) operation. Renal function outcomes and perioperative complications were assessed.
Results
All 54 patients were successfully operated without conversion to open surgery. The use of the LAB in laparoscopic renal tumor SE operation can shorten the warm ischemia time ([WIT], LAB 12.92 ± 8.38 min vs. LA 17.89 ± 6.73 min) and increase the zero ischemia (ZI) rate (LAB 23.08% vs. LA 3.57%). In the one-year follow-up, the LAB group showed quicker renal function recovery (ipsilateral renal function 3 months after the surgery, LAB 41.67 ± 10.11% vs. LA 36.75 ± 10.30%). The limitations of this study were limited number of patients and retrospective attribute.
Conclusion
The new LAB could aspirate and expose the operative field with a single instrument. In operations that need to expose and aspirate simultaneously, such as in renal tumor simple enucleation, it could shorten WIT and improve the postoperative renal function recovery.
Effect of preceding antiplatelet agents on ischemic stroke severity in patients with a history of stroke
Authors: Yamada Takehiro , Tanaka Eijirou , Kishitani Toru , Kojima Yuta , Nakashima Daisuke , Kitaoji Takamasa , Teramukai Satoshi , Nagakane yoshinari
Published: March 2022

Background: Antiplatelet agents are effective in secondary prevention of ischemic stroke and can reduce the severity of first-ever ischemic stroke. However, it remains controversial whether prophylactic administration of antiplatelet agents can reduce the severity of recurrent ischemic stroke. This study aimed to determine the effect of preceding antiplatelet treatment on ischemic stroke severity in patients with a prior history of stroke.Methods: From the prospective hospital registry of 1338 consecutive patients with ischemic stroke within 7 days of symptom onset, we identified patients with a prior history of stroke who were admitted due to cerebral thrombosis, which included large-artery atherosclerosis, small vessel occlusion, and branch atheromatous disease. Patients were categorized into 2 groups according to preceding medication: antiplatelet (AP) group and none (N) group. Those with preceding anticoagulant agents or unknown prior medication were excluded. Stroke severity (National Institutes of Health Stroke Scale: NIHSS) on admission was compared between the 2 groups.Results: A total of 88 patients were analyzed. Out of these, 66 were identified in the AP group (median age 78, male 71%), and 22 in the N group (median age 71, male 73%). The median NIHSS on admission was lower in the AP group than in the N group (3 vs 5, p=0.043). In multivariate analysis, preceding antiplatelet treatment was independently associated with mild stroke (NIHSS ≤4) on admission (odds ratio 5.77, 95% confidence interval 1.73-21.6, p=0.004).Conclusion: Preceding antiplatelet treatment in patients with a prior history of stroke may reduce the severity of subsequent cerebral thrombosis.
‹Postdigitales Schultheater›
Authors: Traulsen Sören Jannik , Büchner Felix
Published: March 2022

Der vorliegende Beitrag dient als Grundlage zur Theoretisierung und Konzeptualisierung des ‹Postdigitalen Schultheaters›. Ausgangspunkt sind theoretische Überlegungen, die den Postdigitalitätsbegriff aus kultur- und medienwissenschaftlicher Perspektive mit aktueller Forschung zur Digitalisierung in der Kulturellen Bildung und schlussendlich mit zeitgenössischen Konzeptualisierungen von theaterpädagogischer (Schul-)Praxis verbinden. Als wichtiger Einflussfaktor für das Postdigitale Schultheater werden dabei u. a. digitale Transformationsprozesse innerhalb der Theaterkunst (als zentrale Bezugskunst des Schultheaters) im Zuge der ‹Postdigital Condition› identifiziert. Um diese Transformationsprozesse zu ergründen, wurden zwei zentrale Forschungsfragen aufgestellt: (1) ‹Wer spricht wie über Theater und Digitalität?› und (2) ‹Welche Implikationen erschliessen sich daraus für das Postdigitale Schultheater?›. Die Analyse des aktuellen Diskurses um ‹Theater und Digitalität› ergab, dass sich vier idealtypische Positionen bestimmen lassen, die insbesondere durch ihre Verortung des ‹Digitalen› im Theater zu unterscheiden sind. Das Digitale ist demnach entweder im Spiel mit Medientechnologien auf der Bühne, in der Lebenswelt zeitgenössischer Theatermachender als ‹Digital Natives›, in den strukturellen Beschaffenheiten des Internets oder in der Ästhetik einer theatralen ‹Post-Internet-Art› zu finden. Bezüglich der theaterpädagogischen (Schul-)Praxis wurde aus diesen Positionen jeweils eine zugespitzte und diskussionsanregende These für das Postdigitale Schultheater abgeleitet.
Agronomic performance, flowering, physicochemical characteristics and genetic divergence in garlic accessions from Brazil
Authors: Taula António Jorge Viegas , Júnior Valter Carvalho de Andrade , Resende Francisco Vilela , Brito Orlando Gonçalves , Silva Jeferson Carlos de Oliveira , Perreira Alysson Gomes
Published: March 2022

The evaluation of garlic accessions is important in the search for superior, adapted and flowering cultivars for botanical seed production. The objective of this work was to assess the agronomic performance, flowering capacity and genetic divergence of 13 experimental garlic accessions bred in Brazil. The experiment was laid out as a completely randomized block design with four replications at Lavras, Minas Gerais, Brazil from May to October 2018. A total of 11 accessions were experimental and two were control varieties, Quitéria and Caçador. The control varieties are commercially produced in Brazil and the 11 experimental accessions are elite. The emergence, emergence speed index, plant height, percentage of overcrowding, average weight of commercial bulb, number of bulbs per bulb, total yield, commercial yield, flowering percentage, length and diameter, soluble solids, titratable acidity, pH and ratio soluble solids and titratable acidity of the exhaust floral were measured. The data obtained were submitted to analysis of variance (p≤0.05), and when significant the effects of genotypes, their means grouped by the Scott-Knott test. We also proceeded to study genetic divergence through multivariate analysis, adopting the canonical variables technique. Variance analysis indicated significant differences between genotypes for emergence speed index, flowering percentage, floral scape diameter, floral scape length and commercial yield. The highest commercial yield and flowering percentage were observed in RAL (8.82 t ha-1) and DDR 6024 (80.92%) access, respectively, which differed only from commercial cultivars (Quitéria and Caçador). The greatest genetic divergence was verified between experimental accessions and commercial cultivars. The experimental accessions presented flowering potential and botanical seed production in the studied region
Inulin content of Jerusalem artichoke (Helianthus tuberosus L.) tubers stored at 5 oC in a refrigerator for different durations
Authors: Sennoi R. , Puttha R.
Published: March 2022

Jerusalem artichoke is a perennial crop, but it is grown as an annual crop for its inulin containing tubers. Various factors affect inulin content, in which storage duration is one of the significant causes. Therefore, the effect of different storage durations on inulin content of Jerusalem artichoke was investigated in this study. Four Jerusalem artichoke varieties were assigned as factor A, and six durations of storage at 5 oC were assigned as factor B. The 24 treatment combinations of a 4×6 factorial were arranged in a completely randomized design with four replications. After harvest, the tubers were cleaned and stored at 5 oC for five months. Inulin content was analyzed consecutively at 0, 1, 2, 3, 4 and 5 months after storage. Times of storage and varieties were significantly different (P<0.01) for inulin content. Stored tubers had inulin contents ranging from 35.9 to 43.7 % compared to 47.8 % of freshly-harvested tubers. The lowest inulin content was found after 2 months of storage. JA 89 had the highest inulin content (47.80%), whereas CN52867 had the lowest inulin content (35.85%). Regression analysis showed small and insignificant effect of storage time on inulin content, and the results are discussed. The results will be useful for consumers and industries for their concern on storage loss of inulin content after storage
Physiological, biochemical and nutritional changes in soybean in response to application of steel slag
Authors: Silva Alessandra Vieira da , Deus Angélica Cristina Fernandes , Souza Mara Lúcia Cruz de , Broetto Fernando , Büll Leonardo Theodoro
Published: March 2022

Steel slag is a powdery industrial residue that has CaO, MgO and SiO2 in its composition, which enables its use in agriculture for soil acidity correction. Most studies involving this residue have focused on understanding its effects on the soil, not always considering its action on the plant metabolism. Thus, the present study aimed to evaluate physiological, biochemical and nutritional changes in soybean plants due to application of lime and steel slag on the soil surface or by incorporation. The experiment was carried out in the field, with six soil acidity corrective materials: stainless steel slag, steel slag, ladle slag, wollastonite rock, dolomitic lime and calcined dolomite, plus a negative control, which did not receive correctives. Two application methods were adopted: soil surface application or incorporation. Sixty days after application, the soybean crop was established. Soybean response changed with the application method, since incorporation of corrective materials provided greater production of fresh and dry leaf mass and stem fresh mass, increased chlorophyll b and leaf K levels, and contributed to a greater number of plants per hectare and pods per plant, compared to surface application. Besides such benefits, there was no difference between the effect of application methods on soybean yield, indicating that both incorporation and surface application are efficient in increasing soybean grain yield. The correctives steel slag, wollastonite and calcined dolomite provided significant increases in soybean yield
Quantitative expression analysis of different cold-responsive (COR) and C-repeat binding factors (CBF) genes in wild and cultivated barley under cold acclimation conditions
Authors: Hazrati Nahid , Hasanzadeh Mohammad , İkincikarakaya Saime Ünver , Özmen Canan Yüksel , Ergül Ali
Published: March 2022

Cold stress affects plant metabolism and transcripts. The effect on plant metabolism was caused both by direct inhibition of metabolic enzymes at cold temperatures and by reprogramming the gene expression. The main objective of this study was to evaluate and identify of expression level of some cold-related genes under control and cold stress conditions in 11 spring/winter barley (Hordeum vulgare L.) varieties and 2 Hordeum spontaneum wild genotypes. For this purpose, expression profile of the main C-repeat binding factor )CBF( genes along with expression profiles of the two cold-responsive )COR( genes in plants exposed to low temperatures (+4 °C) were investigated. In parallel, measurements of leaf water potential of varieties were performed in control and at low temperature conditions. Results revealed that, the expression level changes of COR14b gene under cold conditions are more consistent with those of the upstream CBF9 gene expression levels in different varieties and time points rather than the other upstream gene (CBF1). The dehidrin8 )DHN8( expression level was also related to the CBF9 gene expression level and the decreased expression of the CBF9 gene resulted in decreased expression or non-expression of the DHN8 gene. Based on results, it could be said that CBF9 interacts with CBF1 to regulate DHN8 expression. Wild genotypes showed statistically insignificant expression increment for investigated genes in days 1 and 8 of stress. This result is an indicator of the increase at expression levels in the stress genes of more tolerant varieties
Evaluation of regrowth ability of soybeans for forage utilization under two-cutting systems
Authors: Prasojo Yogi Sidik , Ishigaki Genki , Hashiguchi Masatsugu , Muguerza Melody , Akashi Ryo
Published: March 2022

Soybean (Glycine max) has the potential as forage feed because of its high protein content and low fiber. Intercropping soybean with tropical forage grasses can improve forage quality and increase yield. However, their optimum cutting interval under mixed cropping system is still unknown. This study aimed to investigate regrowth ability and performance of soybean plant under two different cutting heights in Miyazaki, Southwestern of Japan, which has a humid subtropical climate with relatively high temperature and evenly distributed precipitation throughout the year. The experimental design was randomized block design arrange in 3  2 factorial scheme (soybean cultivars  cutting treatments). Three soybean accessions (Glycine max ‘Fukuyutaka’, G. max ‘Kohamdaizu’ and G. gracilis ‘Moshidou Gong 503’) with 5 replications were cultivated under single seeding condition. Soybeans were defoliated after 50 d of cultivation under low level cutting height (LC, 7.5 cm) and high level cutting height (HC, 12 cm). ‘Fukuyutaka’ achieved 100% regrowth rate in both LC and HC. Although the regrowth rate for ‘Kohamadaizu’ was 100% in the HC, it was only 20% in LC. ‘Fukuyutaka’ was more robust and high tolerant for defoliation stress than that of ‘Kohamadaizu`. In other hand, no plants exhibited regrowth in both cutting heights for ‘Moshidou Gong 503’. For ‘Fukuyutaka’ and ‘Kohamadaizu’, the number of branching nodes with re-emergent leaves was significantly higher in the HC. In both cutting height of ‘Fukuyutaka’, plant continued elongating and exhibited vigorous growth until 2nd cutting. The cutting height levels, height of cotyledonary node and growth stage of soybean plant when harvested at the 1st cutting significantly affected the regrowth ability of soybeans. In conclusion, ‘Fukuyutaka’ showed the ability for regrowth under LC and HC. HC provided significantly higher fresh matter and dry matter weight than that LC. Further study is needed to evaluate the performance of ‘Fukuyutaka’ under intercropping cultivation with tropical forage grasses. This is the first report to establish an approach for two-cutting soybean as forage
Susceptibility of Urochloa species subjected to pre-emergence application of [imazapyr + imazapic] herbicide
Authors: Santos Fenelon Lourenço de Sousa , Nascente Adriano Stephan , Lacerda Mabio Chrisley , Calil Francine Neves , Araújo Fernando Couto de
Published: March 2022

Intercropping imidazolinone resistance crops, resistant to herbicides imazapyr + imazapic, with forage species may be a viable alternative to recover degraded pasture areas. This practice requires herbicides to slow down development of the forage and avoid reduced rice yield. However, as it is a relatively new technology, the proper management of this herbicide to control forage is not known. The objective of this study was to determine the susceptibility of forages Urochloa ruziziensis, U. brizantha cv. Paiaguás, and U. brizantha cv. Marandu, submitted to the pre-emergence application of the herbicides [imazapyr + imazapic]. The experimental design was completely randomized in a 3×5+3 factorial scheme with five replications. Treatments consisted of the combination of the three species (Urochloa ruziziensis, U. brizantha cv. Paiaguás, and U. brizantha cv. Marandu) and five intervals between herbicide application in the soil and forage sowing (0; 5; 10; 15; and 20 days after its application), in addition to three control treatments, without herbicide application. This study found that application of herbicide on the day of forage sowing for intercropping with imidazolinone resistance crops is not feasible. Increasing the time interval between herbicide application and forage sowing provides increased development of U. brizantha cvs. Marandu and Paiaguás. The species U. ruziziensis is more susceptible to pre-emergence application imazapyr + imazapic. According to the results, U. brizantha cvs. Marandu and Paiaguás are more suitable to be managed by imidazolinone herbicides to recover degraded pasture areas
Effects of mulching on the weed community and grain yield of upland rice cultivars
Authors: Alves Givago Lopes , Santos Raimundo Nonato Viana , Rodrigues Antônia Alice Costa , Correa Maria José Pinheiro , Mesquita Mário Luiz Ribeiro , Silva Maria Rosângela Malheiros
Published: March 2022

This study evaluated the effects of mulching on upland rice cultivars Comecru and Cambará and the weed community under four amounts of babassou (Attalea speciosa Mart. ex Spreng.) straw mulching namely: 0, 15, 20, 25 t ha-1 with a view to control weeds. The experiment was laid out in a randomized complete block design in a 2 x 4 factorial scheme with four replications. The rice plant height, percentage of fertile panicles, number of spikelets per panicle, weight of 100 grains and grain yield were assessed. We also assessed the weed community by computing the following phytosociological parameters: density, frequency and the importance value index (IVI) of each species. Babassou straw mulching reduced weed density and dry mass between rows of upland rice cultivars and increased the rice yield. The weed species with the highest Importance Value Index (IVI) in the treatments with no mulching were Cyperus iria, Fimbristylis dichotoma and Digitaria ciliaris. Rice grain yield was increased with the increase in the amount of straw. Comecru cv. had the highest suppressive effect on weeds with significantly higher grain yield (1,214.85 kg-1) than Cambará cv. (878.72 kg ha-1). We conclude that the higher amounts (20 and 25 t ha-1) of babassou straw mulching suppressed weeds, providing less competition with the rice cultivars, which resulted in an increase in the number of rice panicles, weight of 100 grains, spikelet fertility and grain yield in both rice cultivars
Assessment of the state and development trends of the region based on indicators of economic potential (based on the materials of the Novosibirsk region)
Authors: Сигунова Т.А.
Published: March 2022

В статье осуществляется анализ и оценка показателей социально-экономического развития Новосибирской области. Выявлено, что Новосибирская область в настоящее время не реализует накопленный инновационно-научный потенциал, что отражается в относительно низких значениях индикаторов экономического развития. Автором предложена методика оценки экономического потенциала региона на основе использования индикаторов материально-технического, финансово-экономического и инновационно-институционального потенциалов. Предложенная методика, апробированная на примере Новосибирской области, позволяет комплексно оценивать состояние развития региона; выявлять факторы, сдерживающие развитие области, и выявлять тенденции экономического роста. Значения предложенных индикаторов экономического потенциала Новосибирской области сравниваются со средними показателями по России с целью получения объективной оценки состояния развития региона. Анализ тенденций развития Новосибирской области показал, что оценка индикаторов экономического развития постепенно приближается к средней по России, однако регион имеет неиспользованный научный потенциал, эффективная реализация которого позволит продемонстрировать более высокую конкурентоспособность на региональном, страновом и национальном уровне.

The article analyzes and evaluates the indicators of socio-economic development of the Novosibirsk region. It is revealed that the Novosibirsk Region currently does not realize the accumulated innovation and scientific potential, which is reflected in the relatively low values of economic development indicators. The author proposes a methodology for assessing the economic potential of the region based on the use of indicators of material and technical, financial and economic, innovative and institutional potentials. The proposed methodology, tested on the example of the Novosibirsk region, allows us to comprehensively assess the state of development of the region; to identify factors hindering the development of the region, and to identify trends in economic growth. The values of the proposed indicators of the economic potential of the Novosibirsk region are compared with the average indicators for Russia in order to obtain an objective assessment of the state of development of the region. The analysis of trends in the development of the Novosibirsk region showed that the assessment of economic development indicators is gradually approaching the average for Russia, but the region has untapped scientific potential, the effective implementation of which will allow demonstrating higher competitiveness at the regional, country and national levels.
Formation of the industrial policy mechanisms in the conditions of industry 4.0 development
Authors: Юдин Н.Н. , Абрашкин М.С.
Published: March 2022

В статье уточнены механизмы формирования промышленной политики в условиях развития Индустрии 4.0 в России. Методом логико-абстрактного моделирования доказано, что имеющаяся организационно-управленческая структура промышленности не отвечает в полной мере интересам его опережающего развития. Предложен механизм формирования промышленной политики, основанный на трёх последовательных компонентах, необходимых для перехода к Индустрии 4.0. Данный механизм основан на внутриотраслевой и межотраслевой цифровой интеграции хозяйствующих субъектов, развитии частно-государственного партнёрства. Проведен анализ показателей эффективности промышленной политики с точки зрения перехода к Индустрии 4.0.

The article clarifies the mechanisms for the formation of industrial policy in the context of the development of Industry 4.0 in Russia. It has been proved by the method of logical-abstract modeling that the existing organizational and management structure of the industry does not fully meet the interests of its advanced development. A mechanism for the formation of industrial policy is proposed, based on three sequential components necessary for the transition to Industry 4.0. This mechanism is based on intra-sectoral and inter-sectoral digital integration of business entities, the development of public-private partnerships. The analysis of indicators of the effectiveness of industrial policy from the point of view of the transition to Industry 4.0.
Applied mathematical tools of interregional statistics of economic crime
Authors: Ляпин А.Е.
Published: March 2022

В представляемой научной статье нами сконцентрировано внимание на актуальной проблеме комплексного статистического исследования экономической безопасности государства и субъектов рыночной экономики, а также угроз, которые несет собой преступность налоговой и коррупционной направленности. Для исследования такого объекта в научной статье задействован весь статистический инструментарий, представленный методами, классификациями, показателями, специальными приемами, которые на сегодняшний день имеются в багаже статистической науки и практики.

In this scientific article, we focus on the actual problem of a comprehensive statistical study of the economic security of the state and market economy entities, as well as the threats posed by tax and corruption-related crime. To study such an object, the scientific article uses all the statistical tools presented by methods, classifications, indicators, and special techniques that are currently available in the baggage of statistical science and practice.
Features of calculation and problems of administration of value added tax in the implementation of foreign trade activities
Authors: Костин А.А. , Дудкина Д.А.
Published: March 2022

В статье рассмотрены особенности исчисления НДС при совершении торговых операций на внешнем рынке товаров, как с точки зрения их осуществления, так и администрирования. Многосторонний анализ особенностей позволил выявить сложности на конкретных этапах возникновения обязанности уплаты НДС. Сделаны выводы и сформулированы предложения решения существующих проблем.

The article discusses the features of calculating the value added tax when performing trade operations on the foreign market of goods, both from the point of view of their implementation and administration. A comprehensive analysis of the features allowed us to identify difficulties at specific stages of the emergence of the obligation to pay VAT. Conclusions are drawn and proposals for solving existing problems are formulated.
Quality assessment of digital processing of images obtained by aerial photography with unmanned aerial vehicles
Authors: Арешев Д.С.
Published: March 2022

Аэрофотосъемка и воздушная фотограмметрия с использованием беспилотных летательных аппаратов обеспечивают качество фотографий, не уступающее качеству, достигаемому при наземной фотосъемке, вместе с тем, использование беспилотных летательных аппаратов предоставляет более широкие возможности для формирования трехмерных изображений различных объектов, по сравнению с наземной фотосъемкой. Цифровая обработка видеоинформации, полученной при помощи фотокамеры, установленной на беспилотном летательном аппарате, требует проведения большого объема вычислений, поэтому актуальной задачей является оценка качества получаемого изображения для оптимизации алгоритмов обработки.

Aerial photography and aerial photogrammetry with unmanned aerial vehicles provides photo quality not worse than the quality оf ground photography, however unmanned aerial vehicles provides more potential for getting 3D images of various objects than ground photography. Digital processing of video information obtained with a camera mounted on an unmanned aerial vehicle requires a great amount of calculations therefore quality assessment of the resulting images is an actual task to optimize processing algorithms.