bluuebunny/crossref_metadata_2025 huggingface dataset:
Teaching About Partnerships Between Patients and the Team: Exploring Student Perceptions
Authors: Langlois Sylvia , Mehra Kamna
Published: June 2020

Health profession educators are responding to shifting approaches where patients are increasingly recognized as partners in an interprofessional care process. To foster competencies related to partnerships between patients and the team, educators have advanced the role of patient partners; however, an appreciation of resulting student learning is in its early stages. First-year students from 9 programs interacted with patient partners and participated in a Reader’s Theater that explored partnerships with patients in an interprofessional team. Students completed reflective assignments; an inductive thematic analysis explored student learning. The following 4 overarching themes were recognized: developing insights through patient perspective, promoting partnerships with patients, recognizing attitudes that promote therapeutic relationships, and advocating for the patient to be a team member. Accompanying subthemes provide enhancement of each of the identified themes. Students discussed the effect of poor collaboration, identified attitudes that promote collaboration, and expressed the value of advocacy for patient partnership. An enriched appreciation of student learning will guide educator engagement of patient partners in both health professional and interprofessional curricula.
Isselite, Cu6(SO4)(OH)10(H2O)4⋅H2O, a new mineral species from Eastern Liguria, Italy
Authors: Biagioni Cristian , Belmonte Donato , Carbone Cristina , Cabella Roberto , Demitri Nicola , Perchiazzi Natale , Kampf Anthony R. , Bosi Ferdinando
Published: June 2020

The new mineral isselite, Cu6(SO4)(OH)10(H2O)4⋅H2O, has been discovered in the Lagoscuro mine, Monte Ramazzo mining complex, Genoa, Eastern Liguria, Italy. It occurs as sprays of blue acicular crystals, up to 0.1 mm long, associated with brochantite and posnjakite. Streak is light blue and the lustre is vitreous. Isselite is brittle, with irregular fracture and good cleavage on {001} and {100}. Measured density is 3.00(2) g/cm3. Isselite is optically biaxial (–), with α = 1.599(2), β = 1.633(2) and γ = 1.647(2) (determined in white light). The measured 2V is 63.6(5)°. Dispersion is moderate, withr>v. The optical orientation isX=b,Y=candZ=a. Isselite is pleochroic, withX= light blue,Y= blue,Z= blue;X<<Z<Y. Electron microprobe analyses give (wt.%): SO311.45(21), MgO 0.31(7), CoO 1.07(14), NiO 9.41(90), CuO 51.29(126), ZnO 1.10(20), H2Ocalc24.21, total 98.84. The empirical formula of isselite, based on Σ(Mg,Co,Ni,Cu,Zn) = 6 atoms per formula unit, is (Cu4.80Ni0.94Co0.11Zn0.10Mg0.06)Σ6.00(S1.06O4.19)(OH)10⋅5H2O. Isselite is orthorhombic, space groupPmn21, with unit-cell parametersa= 6.8070(14),b= 5.8970(12),c= 20.653(4) Å,V= 829.0(3) Å3andZ= 2. The crystal structure of isselite was refined from single-crystal X-ray diffraction data toR1= 0.067 on the basis of 2964 reflections withFo> 4σ(Fo). It shows a layered structure formed by zig-zag {001} layers of Cu-centred polyhedra. Sulfate groups occur in the interlayer along with one H2O group. Isselite is chemically related to redgillite and montetrisaite.
Bromide impairs the circadian clock and glycolytic homeostasis via disruption of autophagy in rat H9C2 cardiomyocytes
Authors: Jiang Yicheng , Gu Yang , Xu Hai , Tian Xiaoyi , Zhang Xuefeng , Xu Xiaojin , Yan Wenting , Zhang Xiwen
Published: June 2020

Background

Trace elements function as essential cofactors that are involved in various biochemical processes in mammals. Autophagy is vital for nutrient supplement, which is an important Zeitegber for the circadian homeostasis in heart. Here, we considered the possibility that autophagy, as well as the cardiomyocyte clock and glycolysis are interlinked. Detrimental effects were observed when cardiac system is exposed to bromine containing drugs. This study investigated the effects and mechanisms of bromide on the circadian clock and glycolytic metabolism of H9C2 cardiomyocytes.

Results

In the present study, bromide does not affect cell viability and apoptosis of H9C2 cardiomyocytes. Bromide dampens the clock and glycolytic (Hk2 and Pkm2) gene expression rhythmicity in a dose-dependent manner. Additionally, bromide inhibits autophagic process in H9C2 cardiomyocytes. In contrast, rapamycin (an autophagy inducer) dramatically restores the inhibitory effect of NaBr on the mRNA expression levels of clock genes (Bmal1, Cry1 and Rorα) and glycolytic genes (Hk2 and Pkm2).

Conclusions

Our results reveal that bromide represses the clock and glycolytic gene expression patterns, partially through inhibition of autophagy.
The introduction of mindfulness groups to a psychiatric rehabilitation in-patient setting: a feasibility study
Authors: Millar Audrey , Tip Liesbeth , Lennon Ruth , Macinnes Marlene , Michalska Beata , Lawrie Stephen M , Schwannauer Matthias
Published: June 2020

Background

Patients within psychiatric rehabilitation services have multiple, complex and enduring difficulties, and are frequently described as ‘treatment resistant’. This group have diagnoses of major mental health conditions, most commonly schizophrenia, often alongside a history of complex trauma, co-morbid alcohol/ substance misuse, and cognitive impairment. There is no known effective medical treatment other than Clozapine in this patient group, however, there is preliminary evidence that mindfulness can help individuals with psychosis by improving their ability to cope with stressful internal experiences. This study aimed to determine if mindfulness practice groups are an acceptable therapeutic intervention in an in-patient rehabilitation setting. The study also aimed to monitor the well-being of those who participated.

Methods

Mindfulness practice groups were offered three times weekly on a 15-bedded rehabilitation ward in a psychiatric hospital over 5 months, and weekly in a second ward over an 18 month period. The sessions were delivered by Clinical Psychologists in accordance with adaptations for a psychosis population. Attendance data were gathered on both wards and additional measures of well-being were collected on one ward. Qualitative interviews were conducted with a sample of patients, group facilitators, and staff, to provide supplementary information about the acceptability of the intervention.

Results

In both wards around two thirds (65, 67%) of in-patients attended at least one group and smaller proportion (around a third) went on to attend regularly. There was no discernible impact on well-being using the Warwick-Edinburgh well-being scale. Qualitative interviews suggested a number of benefits to individuals attending as well as the potential for groups to enhance the therapeutic culture within wards.

Conclusions

Clinical guidelines suggest that all patients with a diagnosis of psychosis should have access to psychological therapies, but delivering psychological therapy within an in-patient rehabilitation setting can be challenging. This preliminary feasibility study suggests that mindfulness practice groups are an acceptable intervention, and that further research to look at the effectiveness of mindfulness for symptoms of treatment-resistant psychosis is both possible and merited.
Early upregulation of AR and steroidogenesis enzyme expression after 3 months of androgen-deprivation therapy
Authors: Hamid Agus Rizal A. H. , Kusuma Putra Harun W. , Sari Ningrum Paramita , Diana Putri , Sesari Saras Serani , Novita Eka , Gultom Fajar Lamhot , Saraswati Meilania , Tanurahardja Budiana , Asmarinah  , Umbas Rainy , Mochtar Chaidir A.
Published: June 2020

Background

Androgen deprivation therapy (ADT) is a standard treatment for advanced prostate cancer (PCa). However, PCa recurrence and progression rates during ADT are high. Until now, there has been no evidence regarding when progression begins. This study evaluated the gene expression of intraprostatic androgen receptor (AR) and steroidogenic enzymes in the early stages of ADT.

Methods

Prostate tissue samples were taken from PCa patients with urinary retention who received ADT (ADT-PCa; n = 10) and were further subgrouped into ADT ≤12 months (n = 4) and ADT > 12 months (n = 6). The ADT-PCa tissues were then compared with BPH (n = 12) and primary (no treatment) PCa tissues (n = 16). mRNA for gene expression analysis of AR and steroidogenic enzymes was extracted from formalin-fixed paraffin embedded (FFPE) tissues and analyzed by real-time PCR. Protein expression was evaluated by immunohistochemistry with specific antibodies.

Results

AR gene expression was higher in the ADT-PCa group than in the BPH or primary PCa group. Both the ADT ≤12 and > 12 months subgroups had significantly higher relative gene expression levels of AR (p < 0.01 and 0.03, respectively) than the primary PCa group. In the ADT-PCa group, AR protein expression showed an increasing trend in the ADT ≤12 months subgroup and was significantly elevated in the ADT > 12 months subgroup compared with the PCa group (100%; p < 0.01). Half (50%) of the patients in the ADT ≤12 months subgroup were found to have upregulation of AR, and one showed upregulation beginning at 3 months of ADT. A trend toward elevated relative gene expression of SRD5A3 was also apparent in the ADT groups.

Conclusion

AR and steroidogenic enzymes are upregulated in ADT-PCa patients as early as 3 months, without PSA elevation. Steroidogenic enzymes, particularly SRD5A3, were also upregulated before PSA rose.
Comparison of the effect of rapeseed oil or amaranth seed oil supplementation on weight loss, body composition, and changes in the metabolic profile of obese patients following 3-week body mass reduction program: a randomized clinical trial
Authors: Moszak Małgorzata , Zawada Agnieszka , Juchacz Aldona , Grzymisławski Marian , Bogdański Paweł
Published: June 2020

Background

Amaranth seed oil (ASO) and rapeseed oil (RSO) are functional foods that display antioxidant and hepatoprotective properties. These oils are also known to lower glucose and cholesterol levels. The current study compared the effects exerted by RSO and ASO on weight loss and metabolic parameters during a 3-week body mass reduction program.

Methods

Eighty-one obese subjects (BMI > 30 kg/m2), aged 25–70 years, were enrolled in a 3-week body mass reduction program based on a calorie-restricted diet and physical activity. Participants were randomly categorized into an AO group (administered 20 mL/d of ASO), a RO group (administered 20 mL/d of RSO), and a C group (control; untreated). Anthropometric and metabolic parameters were measured at baseline and endpoint.

Results

Significant decreases in weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), fat mass (FM), lean body mass (LBM), visceral fat mass (VFM), and total body water (TBW%) were observed in all groups (P <  0.05). No significant improvements were observed in the clinical parameters of group C. Fasting insulin (Δ − 5.9, and Δ − 5.7) and homeostatic model assessment of insulin resistance (HOMA-IR) (Δ − 1.1 and Δ − 0.5) were decreased in both RO and AO groups, respectively. Fasting glucose (Δ -8.5; P = 0.034), total cholesterol (Δ -14.6; P = 0.032), non-HDL cholesterol (Δ 15.9; P = 0.010), TG/HDL ratio (Δ -0.6; P = 0.032), LDL cholesterol (Δ -12.3; P = 0.042), and triglycerides (Δ -6.5; P = 0.000) were significantly improved in the AO group, compared to the RO group.

Conclusions

The 3-week body mass reduction intervention caused a significant reduction in the weight, BMI, WC, HC, FM, and VFM of all groups. Except for HOMA-IR, there were no statistical differences between the clinical parameters of all groups. However, a trend toward improved insulin levels and HDL% was noticeable in AO and RO. Therapies involving edible oils with high nutritional value, such as RSO and ASO, show potential for improving metabolic measurements during body mass reduction programs. Thus, obese patients undertaking weight reduction programs may benefit from RSO and ASO supplementation.

Trial registration

retrospectively registered, DRKS00017708.
LAIR-1 overexpression inhibits epithelial–mesenchymal transition in osteosarcoma via GLUT1-related energy metabolism
Authors: Zhang Jinxue , Zhang Yuan , Cheng Shiyang , Mu Yang , Liu Yongming , Yi Xin , Jiang Dongxu , Ding Yong , Zhuang Ran
Published: June 2020

Background

Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is a collagen receptor belonging to the immunoglobulin superfamily. Although previous studies have evaluated the biological role of LAIR in solid tumors, the precise mechanisms underlying the functions of LAIR-1 as a regulator of tumor biological functions remain unclear.

Methods

LAIR-1 expression was evaluated by immunohistochemical analysis using an osteosarcoma (OS) tissue microarray. Wound healing and transwell migration assays were performed to evaluate tumor cell migration. Quantitative real-time polymerase chain reaction (qPCR) and western blotting were conducted to detect the expression of epithelial–mesenchymal transition (EMT)-related molecules. RNA-sequencing (RNA-seq) was conducted to evaluate the mRNA expression profiles after overexpressing LAIR-1 in OS cells. Glucose transporter (Glut)1 expression in OS cells was evaluated by western blotting.

Results

LAIR-1 expression was significantly different between the T1 and T2 stages of OS tumors, and it inhibited OS cell migration. LAIR-1 expression was inversely correlated with the expression of Twist1, an EMT-associated transcription factor, via the Forkhead box O1 signal transduction pathway. Furthermore, RNA-seq and qPCR demonstrated that the expression of EMT energy metabolism-related molecules was significantly reduced after LAIR-1 overexpression.

Conclusions

LAIR-1 overexpression decreased the expression of Glut1 and inhibited the expression of EMT-related molecules in OS cells. These findings provide new insights into the molecular mechanism underlying OS progression.
Neurological phenotypes in patients with NLRP3-, MEFV-, and TNFRSF1A low-penetrance variants
Authors: Mulazzani Elisabeth , Wagner Danny , Havla Joachim , Schlüter Miriam , Meinl Ingrid , Gerdes Lisa-Ann , Kümpfel Tania
Published: June 2020

Background

Neurological manifestations and the co-occurrence of multiple sclerosis (MS) have been reported in patients with autoinflammatory diseases (AID) and variants of the NLRP3-, MEFV-, or TNFRSF1A gene. However, type and frequency of neurological involvement are widely undetermined.

Methods

We assessed clinical characteristics of 151 (108 with MS) patients carrying NLRP3-, MEFV- and TNFRSF1A low-penetrance variants  from the Institute of Clinical Neuroimmunology. We evaluated demographic, genetic, and clinical features with a focus on central nervous system (CNS) involvement including magnetic resonance imaging (MRI) results and cerebrospinal fluid (CSF) data. The disease course of AID patients with MS was compared to a matched MS control group without mutations.

Results

The genetic distribution comprised 36 patients (23%) with NLRP3- and 66 patients (43%) with TNFRSF1A low-penetrance variants as well as 53 (34%) patients carrying pathogenic mutations or low-penetrance variants in the MEFV gene. MS patients displayed most frequently the R92Q TNFRSF1A variant (n = 51; 46%) followed by the Q703K NLRP3 variant (n = 15; 14%) and the E148Q substitution (n = 9; 8%) in the MEFV gene. The disease course of MS was not influenced by the genetic variants and did not differ from MS patients (n = 51) without mutations. AID patients without MS most frequently harbored MEFV mutations (n = 19, 43%) followed by NLRP3- (n = 17, 39%) and TNFRSF1A (n = 8, 18%) low-penetrance variants. Sixteen (36%) of them suffered from severe CNS involvement predominantly recurrent aseptic meningoencephalitis and optic neuritis accompanied by abnormal MRI and CSF results. Severe CNS inflammation was associated with the Q703K allele. Headache was a highly prevalent neurological symptom (up to 74%), irrespective of the underlying genetic variation. The NLRP3 cohort without MS more frequently exhibited affections of the cranial nerves (CN) (p = 0.0228) and motor symptoms (p = 0.0455). Elevated acute-phase reactants were detected in all patients, and fever episodes were present in up to 50%. Arthralgias were the most frequently identified constitutional symptom among all subgroups.

Conclusions

Our data highlight the high prevalence of neurological manifestations, including concomitant MS, among NLRP3-, MEFV-, and TNFRSF1A low-penetrance variants. In particular, patients carrying the Q703K NLRP3 variant are at risk for severe CNS inflammation and CN affection.
On a fractional hybrid version of the Sturm–Liouville equation
Authors: Charandabi Zohreh Zeinalabedini , Rezapour Shahram , Ettefagh Mina
Published: June 2020

It is well known that the Sturm–Liouville equation has many applications in different areas of science. Thus, it is important to review different versions of the well-known equation. The technique of α-admissible α-ψ-contractions was introduced by Samet et al. in (Nonlinear Anal. 75:2154–2165, 2012). Our aim in this work is to study a fractional hybrid version of the Sturm–Liouville equation by mixing the technique of Samet. In fact, by using the technique of α-admissible α-ψ-contractions, we investigate the existence of solutions for the fractional hybrid Sturm–Liouville equation by using the multi-point boundary value conditions. Also, we review the existence of solutions for a fractional hybrid version of the problem under the integral boundary value conditions. Finally, we provide two examples to illustrate our main results.
More properties of the proportional fractional integrals and derivatives of a function with respect to another function
Authors: Jarad Fahd , Abdeljawad Thabet , Rashid Saima , Hammouch Zakia
Published: June 2020

In this article, we present some new properties of the fractional proportional derivatives of a function with respect to a certain function. We use a modified Laplace transform to find the relation between the derivatives in the Riemann–Liouville setting and the one in Caputo. In addition, we provide an integration by parts formulas related to the considered operators.
Tracking 3D seismic horizons with a new hybrid tracking algorithm
Authors: Gogia Rahul , Singh Raman , de Groot Paul , Gupta Harshit , Srirangarajan Seshan , Phirani Jyoti , Ranu Sayan
Published: June 2020

We have developed a new algorithm for tracking 3D seismic horizons. The algorithm combines an inversion-based, seismic-dip flattening technique with conventional, similarity-based autotracking. The inversion part of the algorithm aims to minimize the error between horizon dips and computed seismic dips. After each cycle in the inversion loop, more seeds are added to the horizon by the similarity-based autotracker. In the example data set, the algorithm is first used to quickly track a set of framework horizons, each guided by a small set of user-picked seed positions. Next, the intervals bounded by the framework horizons are infilled to generate a dense set of horizons, also known as HorizonCube. This is done under the supervision of a human interpreter in a similar manner. The results show that the algorithm behaves better than unconstrained flattening techniques in intervals with trackable events. Inversion-based algorithms generate continuous horizons with no holes to be filled posttracking with a gridding algorithm and no loop skips (jumping to the wrong event) that need to be edited as is standard practice with autotrackers. Because editing is a time-consuming process, creating horizons with inversion-based algorithms tends to be faster than conventional autotracking. Horizons created with the adopted algorithm follow seismic events more closely than horizons generated with the inversion-only algorithm, and the fault crossings are sharper.
Pre-operative predicting factor in visual outcome after macular hole surgery
Authors: Feroz Lubna , Rizvi Syed Fawad , Naz Saliha , Khan Tanweer Hassan
Published: June 2020

Objective: To determine the effectiveness of macular hole index (MHI) as a predicting factor of visual outcome after full thickness macular hole surgery.

Methods: This quasi-experimental study was conducted at LRBT Free Base Eye Hospital, Karachi from January 2018 to March 2019. Total 45 eyes of 45 patients with full thickness macular hole (FTMH) underwent preoperative Best Corrected Visual Acuity (BCVA) assessment with logMar chart and Optical Coherence Tomography (OCT) scanning, with measurement of base diameter and macular hole height. Values were calculated for the macular hole index (MHI), which was taken as the predictive factor. All patients had undergone 25+G trans-conjunctival three ports pars plana vitrectomy, internal limiting membrane peeling, and endo-tamponade of C3F8 (14%). The final visual outcome of all the patients was noted.

Results: Forty-five patients were included for the study, out of which 10 (22.2%) were male and 35 (77.7%) were female. Age ranged from 45-70 years (mean age 57.20±6.47 years). The mean pre-operative visual acuity was 2.46±1.15 logMar and was 3.88±2.00 logMar, post-operatively. Moreover, 27(60.0%) out of 45 patients achieved BCVA (gain of 2 lines of the logMar chart). The average macular hole index was 1.55±0.50 and out of 45, 25 patients had MHI ≥0.5. It was found that patients with macular hole index ≥0.50 showed clinically significant improvement in BCVA in comparison to those who have macular hole index <0.50.

Conclusion: Macular hole index can be used to predict functional success in macular hole surgery.

doi: https://doi.org/10.12669/pjms.36.5.1995

How to cite this:Feroz L, Rizvi SF, Naz S, Khan MTH. Pre-operative predicting factor in visual outcome after macular hole surgery. Pak J Med Sci. 2020;36(5):1053-1057. doi: https://doi.org/10.12669/pjms.36.5.1995

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
SARS-CoV-2: A New Autoimmune Pathology or a step toward deciphering the nature of systemic diseases?
Authors: Belyaeva Elena
Published: June 2020

The Cause of death in SARS-CoV-2 patients is a hyperimmune reaction to the pathogen that resembles a systemic rheumatological pathology, namely, severe lightning - fast variants of its course with adverse outcomes, for example, cata-strophic antiphospholipid syndrome, granulomatosis with polyangiitis with lung lesions, acute systemic lupus erythematosus with polyserositis, hemorrhagic alveolitis, and other multi-organ lesions. Such forms of the disease are rare, but they are united by a special uncontrolled production of molecules that potentiate inflammation, in such quantities that they lose their protective and destructive functions. The basis of organ lesions may be vasculitis of vessels of the microcirculatory bed. Studying the influence of SARS-CoV-2 on the development of a lightning-fast fatal hyperimmune reaction can clarify the etiopathogenesis of systemic rheumatic diseases.
USE OF PERCUTANEOUS CORONARY INTERVENTION IN THE TREATMENT ST ELEVATION MYOCARDIAL INFARCTION
Authors: Kirkina Natal'ya , Kulichenkova Yu.
Published: June 2020

The analytical paper explores the role of percutaneous coronary intervention in the treatment ST elevation myocardial infarction according to studies over the last 5 years. The aim of the study is to consider the sequence of transdermal coronary intervention in the treatment algorithm, the time frame, and the 30-day and 1-year survival rate when using alternative treatments versus transdermal coronary intervention. In conclusion: percutaneous coronary intervention is a priority method of treating acute coronary syndrome with ST segment rise. In patients who found themselves in unaffordable centers for percutaneous coronary intervention, fibrinolysis in situ had a worse prognosis than patient transfer. Fibrinolysis followed by percutaneous coronary intervention is a reasonable alternative when primary percutaneous coronary intervention is not available, especially in patients with early manifestation of symptoms. When comparing patients with timely primary transcutaneous coronary intervention, late reperfusion after ST elevation myocardial infarction leads to reduced myocardial rescue and increased infarction size, hence the time frame is of great importance. In general, patients who underwent percutaneous coronary intervention in interbolinal movement had a higher survival rate for 1 year compared to patients receiving thrombolysis.
The Social Movement of Alexei Navalny
Authors: Savenkov Roman
Published: June 2020

The article focuses on the major stages of development of Alexei Navalny’s social movement in 2017-2019 on the federal and regional levels. The movement aims to form and mobilize the supporters of Alexei Navalny in the movement’s structural elements to carry out opposition activities in large cities. In the long-term, the movement wants their activists to participate in regional and local elections. The movement is developing in the context of slowly growing socio-economic and political dissatisfaction in the country and the government’s aim to restrict public expression of concern. The conditions make the movement look for new formats of manifesting people’s discontent. The weakness of the movement is Alexei Navalny’s non-eligibility to hold the office and absence of Navalny’s political party. His image of a “fringe” and “protesting” politician created by the television media prevents him from becoming a respectable and worthy of support politician for the majority of Russians.
When Will Workers Follow an Algorithm? A Field Experiment with a Retail Business
Authors: Kawaguchi Kohei
Published: June 2020

This paper develops a new algorithm for increasing the revenue in a dynamic product assortment problem. Then, it identifies the challenges faced by managers in practice and discusses the conditions under which workers follow the algorithm. To do so, I conducted a field experiment with a beverage vending machine business. The experiment shows that, on average, workers are reluctant to follow the algorithmic advice; however, the workers are more willing to conform once their forecasts are integrated into the algorithm. Analyses using nonexperimental variations highlight the importance of taking worker and context heterogeneity into account to maximize the benefit from adopting a new algorithm. Higher worker’s regret, sales volatility, and fewer delegations increase the conformity, while they mitigate the effects of integration. Workers avoid high-traffic vending machines and focus on machines with high sales volatility when adopting the algorithm. The effects on the sales are largely similar to the effects on product assortments. The results emphasize the gap between nominal and actual performance of an algorithm and several practical issues to be resolved.

This paper was accepted by Matthew Shum, marketing.
A disputa de Davos entre Ernst Cassirer e Martin Heidegger
Authors: Heidegger Martin , Cassirer Ernst
Published: June 2020

Apresentamos a tradução para a língua portuguesa do “Debate de Davos entre E. Cassirer e M. Heidegger”, ocorrido em 26 de março de 1929. A versão aqui traduzida se baseou na transcrição do original alemão, realizada por Joaquim Ritter e Friedrich Bollnow. Tradução de Adriano Ricardo Mergulhão
LEITURAS DO PODER NA TERCEIRA ERA DA TERRA-MÉDIA: UM ENSAIO BASEADO EM O SENHOR DOS ANÉIS
Authors: Da Silva Nunes Rafael
Published: June 2020

O imaginário se estabelece como um campo fértil para o pensamento das múltiplas relações existentes e experienciadas pela realidade humana. Questões associadas à discussão socioeconômica, física, biótica, política, entre outras, podem ser exploradas a partir de construções que possuem, por base, a imaginação. Neste caso, a literatura surge como um dos instrumentos de representação de realidades (des)conhecidas passíveis de serem lidas sob as múltiplas óticas supracitadas. A obra de J. R. R. Tolkien intitulada de “O Senhor dos Anéis” se apresenta como um arquétipo de uma imaginação complexa na qual diferentes sociedades são apresentadas, relacionando-se interna e externamente de múltiplas maneiras. A obra, a partir da sua própria complexidade, apresenta-se como um excelente palco para o desenvolvimento de inúmeros ensaios sobre diferentes esferas que envolvem a própria percepção humana da realidade. Uma das esferas mais discutidas na obra de Tolkien refere-se à dinâmica do poder que pode ser observado na política entre as múltiplas sociedades existentes na Terra-Média.  Neste sentido, o objetivo do presente estudo é analisar, a partir dessa obra, como o poder é encarado por seus múltiplos personagens (e sociedades), bem como compreender que dinâmica possibilitou o surgimento do poder político na Terra-Média.
Coronavirus - assessing the effects of smoking and vaping
Authors: Cope Graham
Published: June 2020

Can tobacco and e-cigarette use affect the outcomes of COVID-19? Graham Cope looks at the early evidence
High gain amplification up to 100  mJ to 3  J using Yb3+:YAG slab-based cat’s-eye cavities under variable seed and operating conditions
Authors: Jolly A. , Machinet G. , Boullet J.
Published: June 2020

We demonstrate the optical architecture of a fairly compact design at 1030 nm for linear amplification, which enables the combination of very high gains and output energies in a single stage to be operated at room temperature. Gains and energies are experienced in the nanosecond regime up to 20 dB and 120 mJ, respectively, at the same time. This design makes use of a thick slab of

Y

b

3
+

:

Y
A
G

in a scalable cat’s-eye cavity, provided there is uniform edge-pumping and fine control of a number of relevant spatial characteristics regarding the pump and the cavity. Highly variable operating conditions are considered for a comprehensive benchmark of the optical performance. They involve single 3 ns long seed pulses with an energy of 1 mJ, accordingly to more or less gain saturation, together with long bursts of stretched picosecond-long pulses. This gives access to kilowatt-class pulse trains of duration 3–5 ms, with a total energy of up to 3 J and an optical efficiency of 20%–25%, prior to more complete gain saturation.
Insect flight velocity measurement with a CW near-IR Scheimpflug lidar system
Authors: Li Yiyun , Wang Kai , Quintero-Torres Rafael , Brick Robert , Sokolov Alexei V. , Scully Marlan O.
Published: June 2020

Flight velocity measurement is an important aspect of insect research that can aid insect identification and facilitate studies and monitoring of insect movements. We propose a novel scheme for the 1-D flight velocity measurement of insects, based on a near-IR Scheimpflug lidar system. We implement this new technique and apply it to study insects at the Salter Research Farm, Robertson County, Texas. The resolution property perpendicular to the probing direction of the Scheimpflug lidar system is explored and reveals the capability of retrieving the velocity component normal to the probing direction of insects passing through the field of view of our system. We observe a shift in wingbeat frequency, which indicates the presence of new insect species during the multi-day measurement. The study on 1-D flight velocity reveals a net directional movement of insects, providing supportive evidence of the arrival of a new species.
Outcoupling efficiency enhancement of a bottom-emitting OLED with a visible parylene film
Authors: Gasonoo Akpeko , Lee Ye-Seul , Yoon Ji-Hyeon , Sung Baek-Sang , Choi Yoonseuk , Lee Jonghee , Lee Jae-Hyun
Published: June 2020

We have investigated an effective and a single-step chemical vapor deposition (CVD) method to achieve conformal visible poly-dichloro-para-xylylene (parylene C) film for light extraction enhancement in bottom-emitting organic light-emitting diodes (OLEDs) at room temperature. We report that sublimed parylene dimers pyrolyzed between 400 °C and 500 °C resulted in visible parylene films with tunable transmittance and haze, exhibiting light scattering properties due to the formation of uniformly distributed dimer crystals. We achieved a novel conformal visible parylene film with total transmittance and high haze of 79.5% and 93.6%, respectively. It is observed that the outcoupling efficiency of the OLEDs employing the visible parylene film is enhanced up to 45.8%. Additionally, the OLED with the visible parylene light extraction film shows limited angle-dependency of emission spectrum over viewing angles. The single-step room temperature fabrication process of this conformal outcoupling film paves the way to achieving commercial high-performance OLEDs.
Measuring complex correlation matrix of partially coherent vector light via a generalized Hanbury Brown–Twiss experiment
Authors: Dong Zhen , Huang Zhaofeng , Chen Yahong , Wang Fei , Cai Yangjian
Published: June 2020

We introduce an effective method for measuring the spatial distribution of complex correlation matrix of a partially coherent vector light field obeying Gaussian statistics by extending our recently advanced generalized Hanbury Brown–Twiss experiment. The method involves a combination of the partially coherent vector light with a pair of fully coherent reference vector fields and a measurement of the intensity-intensity cross-correlation of the combined fields. We show the real and imaginary parts of the complex correlation matrix can be recovered through a judicious control of the phase delay between two reference fields. We test the feasibility of our method by measuring the complex correlation matrix of a specially correlated radially polarized vector beam and we find the consistence between the experimental results and our general theory. We further show that our complex correlation matrix measurement can be used in reconstructing the polarization states hidden behind a thin-layer diffuser.
Multi-column network for cell counting
Authors: Jiang Ni , Yu Feihong
Published: June 2020

Cell counting is a fundamental but crucial task for microscopic analysis. In this paper, we present a method that can count cells automatically and achieves good accuracy. The algorithm extends the U-net from the single-column to the multi-column to capture the features of cells with various sizes. The general convolutional layers in the U-net body are replaced by residual blocks to help the network converge better. Furthermore, a region-based loss function is designed to guide the model to slide into the proper local minima and avoid overfitting. Experimental results on three public datasets show that the proposed method can handle different kinds of images with promising accuracy. Compared with other state-of-the-art approaches, the proposed approach performs superiorly.
AVALIAÇÃO TRICOGRÁFICA EM CÃES COM MANEJO NUTRICIONAL E AMBIENTES DISTINTOS
Authors: Tonial Alex José , Stefani Pertusatti Nicole , Oro Camila Isadora , Teixeira Tillmann Mariana
Published: June 2020

O tricograma avalia microscopicamente o pelo, considerando isso, o objetivo deste trabalho foi avaliar, qualitativamente e quantitativamente, os pelos de cães atendidos no Hospital Veterinário da Unoesc/Xanxerê (SC), relacionando esses dados de acordo com o manejo nutricional e ambiental de cada paciente. Foram coletados pelos da região da escápula esquerda de 42 cães saudáveis, para avaliação tricográfica de presença/ausência de lesões e das fases do ciclo piloso. Esses animais foram categorizados conforme sua alimentação comercial, se eram alimentados com ração super premium (GSP) ou standard (GS) e tipo de ambiente que habitavam, se eram mantidos em ambiente domiciliar com limpeza diária do local ou ambiente externo com limpeza a cada 30 dias. Foi realizada análise de variância (ANOVA) comparando os dados das avaliações qualitativas e quantitativas do pelo com dados de manejo nutricional. No manejo ambiental, os dados foram relacionados com a presença ou ausência de lesões nos folículos pilosos. Nos grupos GSP e GS houve diferença estatística nas avaliações qualitativas, sendo que os pelos do GSP tiveram menor frequência de alterações no bulbo, cilindros queratossebáceos e tricorrexe nodosa. Quando relacionadas as fases do ciclo piloso com o manejo ambiental, não houve diferenças significativas. Nas avaliações referentes ao local que o animal reside, foi observado que os cães que vivem no interior de casa tiveram menor presença de lesões que os que vivem no pátio. Com este trabalho foi possível concluir que os manejos ambiental e nutricional influenciam os pelos, com relação às variáveis qualitativas e quantitativas avaliadas.
La debida diligencia judicial y la protección de los derechos humanos de las mujeres en contextos de violencia
Authors: Gómez Restrepo Alejandro , Herrera Tovar Diana Fernanda
Published: June 2020

En el presente texto se plasman dos aspectos, primero: el difícil ingreso al sistema de administración de justicia para las mujeres víctimas y, segundo, el predominante panorama de impunidad. Estas situaciones serán vistas desde dos elementos: La debida diligencia como obligación reforzada en materia de derechos humanos y, los derechos a las garantías judiciales y a la protección judicial de las mujeres. Se pretende demostrar que al adoptar medidas de debida diligencia, estas permitan proteger los derechos a las garantías judiciales y la protección judicial de las mujeres en contextos de violencia, especialmente, en aquellos casos de violencia sexual donde se torna más complejo su acceso a la justicia.
Life History Effects on Neutral Diversity Levels of Autosomes and Sex Chromosomes
Authors: Amster Guy , Sella Guy
Published: June 2020

Understanding the determinants of neutral diversity patterns on autosomes and sex chromosomes provides a bedrock for our interpretation of population genetic data...
Actual decomposition of the L2 French noun phrase in the predicate construction in the final written examination
Authors: Kazlauskienė Vitalija
Published: June 2020

The noun phrase (NP), one of the key elements of a sentence, can reveal the characteristics of a learner’s linguistic competence. The present study focuses on actual decomposition of NP in the predicate construction. This is when the attribute elements of a noun phrase are included in the predicate construct as factor-actualized determinants. In this position, the copula verb is merely a grammatical means of allowing the attribute to become a predicate (Gaulmyn, Basset 1991: 177).The aim of the study being a more thorough investigation of the criteria and peculiarities of producing this type of predicate constructs in learner language, the present research is based on the empirical material from the Lithuanian learner corpus. The paper briefly discusses the concept of the predicate construction and describes the process of compiling the learner corpus as well as the principles of data selection. The analysis of the NP in a predicate construction is then presented, and the characteristic cases from the corpus data are examined. The main limitation of the present study is related to the scope of the learner corpus. Having summarized the results of the quantitative and qualitative research, the following conclusions were formulated. The learner language is dominated by NP predicate constructions with an adjective more often than a noun. As to the verb conjunction, the typical attribute verb être ‘to be’ was the only one widely used in the corpus under investigation. The analysis of the corpus data also revealed a number of specific errors that are typical of the learners’ written language. In general, the predictive constructions in the learners’ language are characterized by the omission of redundancy tags in the grammatical categories of gender and number. The analysis of the learner corpus provided a broader look at the NP in a predicate construction, highlighting the simplicity, conciseness and repetition of this construct. The results of the study are important for a more comprehensive description of the learners’ language, for solving problems in foreign language analysis, and for contributing to the quality of teaching and learning the French language.
Heat Recovery Opportunities in a Poultry Slaughterhouse for Generation of Hot Water: A Case Study on Energy Pro-duction
Authors: Teixeira Gessen Souza , Altafini Carlos Roberto , Kalnin Joanir Luis
Published: June 2020

The aim of this work is to highlight the possibility of energy gains through heat recovery in an industrial plant. It was carried out in a poultry slaughterhouse, which, within its processes, consumes a very high amount of energy in various forms. It shows the usage of steam, its purpose, and why there is currently such a strong dependence on this resource. Alternatives were found for complete replacement of this energy input. In addition to the heat recovery from lubricating oil of air compressors and from refrigerant desuperheating processes after the discharge of the refrigeration compressors, the most interesting alternative was a water heater powered by mixed fuel. The mass of the proposed fuel mixture was 90% made of wood chip with 10% centrifuged sludge from the company effluent treatment station. From measurements made in the productive process relative to the consumption of water for sanitation, and from the availability of residual heat from processes, a water heater working with the mentioned fuel mixture has been proposed, reaching a payback of the investment predicted up to 3 years and 7 months. The project ensured the supply of hot water without using steam at a lower cost, which also achieved significant environmental gains.
Production and Characterization of Activated Carbon from Coal for Gold Adsorption in Cyanide Solutions
Authors: Martínez-Mendoza Karen L. , Barraza Burgos Juan Manuel , Marriaga-Cabrales Nilson , Machuca-Martinez Fiderman , Barajas Mariber , Romero Manuel
Published: June 2020

In this work, activated carbons were produced using coal as raw matter from seven Colombian carboniferous zones. Physical activation was performed in two stages: a carbonization stage with Nitrogen at a temperature of 850 °C and a residence time of 2 h, followed by an activation stage using steam at temperatures of 700 and 850 °C with residence times of 1,5 h and 2,5 h. From the pore volume characterization for the adsorption of gold, two activated carbons from Cundinamarca, obtained at 850 °C (1,5 h), 850 °C (2,5 h), and a commercial carbon (GRC 22) were selected. Gold adsorption tests were performed with those three activated carbons using synthetic aurocyanide solutions and a gold waste solution. The data of the adsorption isotherms were adjusted using the Freundlich adsorption model for the synthetic solution, as well as Langmuir for the waste solution. The results showed that, using a solution of 1 ppm, the activated carbons C-850-2.5 and C- 850-1.5 produced the higher maximum gold loading capacities in the equilibrium (8,7 and 9,3 mg Au/g, respectively) in comparison to the commercial activated carbon (4,7 mg Au/g).  Gold adsorption test using a waste solution (21 ppm of gold) showed that the activated carbon C-850-1.5 had the highest value of adsorption capacity (4,58 mg Au/g) compared to C-850-2.5 (2,95 mgAu /g).
First report of Coenosia attenuata (Stein, 1903) (Diptera, Muscidae) in Uruguay, confirmed by DNA barcode sequences
Authors: Giambiasi Mario , Rodríguez Abel , Arruabarrena Ana , Buenahora José
Published: June 2020

Coenosia attenuata (Stein, 1903) is a predatory fly which feeds on other insects and can be used as a possible biological control agent. We report this insect in Uruguay for the first time. The flies were found in greenhouses on tomatoes and sweet peppers and identified using both DNA barcoding and morphological characteristics.
Antimikrobna aktivnost bakteriocina bakterija mliječne kiseline prema Listeria monocytogenes, Staphylococcus aureus i Clostridium tyrobutyricum u proizvodnji sira
Authors: Dolenčić Špehar Iva , Bendelja Ljoljić Darija , Petanjek Zvjezdana , Zamberlin Šimun , Tudor Kalit Milna , Samaržija Dubravka
Published: June 2020

The generally accepted concept of the necessity of producing safe foods has indirectly influenced the decision to replace chemical preservatives
with natural ones. Bacteriocins, and in particular those synthesized by
lactic acid bacteria (LAB) in the food industry, are considered to be their effective replacement. In controlling the growth of microbial pathogens and/or the occurrence of pathogenic bacteria in food, with the
permitted nisin and pediocin, a significant antibacterial effect has been shown for most LAB bacteriocins. However, the use of purified bacteriocins as bio preservatives in cheese production is limited. To inhibit the growth of bacteria L. monocytogenes, S. aureus and C. tyrobutyricum in cheese, bacteriocinogenic LAB strains contained in primary, adjunct or protective culture are much more acceptable in cheese production.
Microstructure of kajmak skin layer made during kajmak production
Authors: Radovanovic Mira , Nedeljkovic Aleksandar , Miocinovic Jelena , Pavlovic Vladimir , Pudja Predrag
Published: June 2020

Kajmak is a unique dairy product with a long tradition in Balkan countries and the Middle East. Kajmak skin layers are formed during 60 minutes of kajmak production, influencing the quality and determining the structure of the final product. The influence of milk composition and heat treatments (75-95 °C/5min) on the composition, microstructure and protein distribution of kajmak skin layers was investigated in this study. Microstructure was determined using scanning electron microscopy (SEM), while the distribution of protein fractions was studied by SDS PAGE in reducing and non-reducing conditions. Kajmak skin layers obtained from milk treated at common intense heat regime were characterized with β-LG and α-LA mainly as disulfide-linked complexes, while lower temperature (75 °C) caused the presence of whey proteins in dominantly individual form. More severe treatments (85 °C, 90 °C and 95 °C) caused the full involvement of β-LG in the complexes, since a certain amount of α-LA was found as a monomer. The kajmak skin layer composition, severity of the applied milk heat treatment and the linked whey proteins exhibited a very strong influence on kajmak skin layer microstructure. The microstructure of kajmak skin layer with a low fat content and fat/protein (F/P) ratio was characterized by a compact structure with a dense protein matrix. High fat content and F/P ratio resulted in a dispersive form of the stretched protein network. Kajmak skin layers produced from milk with added whey proteins were characterized by fibrous, thread-like segments, due to the incorporated denatured whey proteins, especially linked β-LG.