bluuebunny/crossref_metadata_2025 huggingface dataset:
State of the art of poecilid fish ( Pisces: Poeciliidae) in México
Authors: Martínez Cantera Leonardo , Hernández-López Marcos , Lango- Reynoso, Fabiola
Published: December 2022

ABSTRACT

Objective: To present a review about the knowledge of the fish of the family poecilidade in Mexico.

Design/methodology/approach: The present review was carried out through the search and bibliographic compilation of literature, as well as in the consultation of articles in different databases, for its subsequent analysis.

Results: Mexico has a great diversity of poeciliids with 105 species registered, 64 are endemic, most are in some category of protection, distributed throughout the national territory, mainly in the Usumacinta River basin. In this area, their reproductive biology and feeding have been studied, which vary according to the species. Their culture in Mexico, focuses on the commercialization of ornamental species both native and exotic.

    

 

 

 

 

Limitations on study/implications: The poecilid fishes are a well study group; however, the information about the mexican species is scattered and in different areas are limited.

Findings/conclusions: Mexico is the country with the greatest diversity of poecilid fish worldwide, most of which are in some category of protection, and are a group well distributed throughout the national territory, with potential as environmental indicators and toxicological studies.
TRENDS AND RESEARCH ON COVID-19 AND FARMERS USING VOSVIEWER
Authors: Fkatia Fkatia , Ramírez Vásquez Jesús Daniel , Velasco Velasco Joel , Aguilar-Rivera Noé
Published: December 2022

ABSTRACT

Objective: The aim of this study was to use bibliometric analysis to provide an overview of the empirical and theoretical research that has been carried out with regard to COVID-19 focusing on scientific publications on the topic of farmers.

Design/methodology/approach: The global literature on COVID-19 and agricultural producers (farmers) published between 2019 and 2022 (August 8), was obtained from the SCOPUS database, comprising a total of 665 documents. VOSviewer was used to perform a bibliometric analysis of these papers.

Results: The two countries that published the most research related to the terms studied were the United States and India. Research conducted in these countries was found in the most cited studies. The studies focused on five major topics: agriculture, epidemiology, psychology, economic impact, as well as rural areas and risk determination. The evolution of the topics over time showed that the research originally began with health-oriented studies, and that once the protocols for the return to normal were generated, studies were carried out to visibilize the producers and their challenges during the pandemic in addition to the support strategies that were generated and the impact that the pandemic had on them, as well as on the local, regional, national, and global economy.

Limitations on study/implications: The documents analyzed are exclusive to the SCOPUS database, so literature was excluded from other sources such as Google Scholar or Web of Science, which could contain important information on the subject in relation to other disciplines.

Findings/conclusions: This type of study makes it possible to better understand the current state of the art regarding the effect of COVID-19 on the agri-food sector, thus allowing researchers to visualize the relevance of, and guide, their research on the topic.

Keywords: bibliometric analysis; resilience; farming; SARS-CoV-2; pandemic; farm workers.
Effect of sugar substitution by aguamiel on the physicochemical quality of pear jam pear (Pyrus communis L.)
Authors: Ramírez-Peñaloza Salma , Pérez-Ruiz Rigoberto V. , Ruiz-Hernández Rafael , Aguilar-Toalá José E. , Fabela-Morón Miriam F. , Díaz-Ramírez Mayra
Published: December 2022

Objective: Analyze the effect of the sugar substitution by dehydrated aguamiel on the physicochemical quality of pear jam pear (Pyrus communis L.)  

Design/methodology/approach: Different levels of sugar substitution by dehydrated aguamiel were analyzed (0, 25 and 50%). Physicochemical parameters on pear jam as color, pH, acidity, density, consistency and soluble solids were evaluated.

Results:  Results showed that the physicochemical and color characteristics of the pear jam was changed by the substitution of sugar by dehydrated aguamiel  

Study limitations/implications: More studies related to sensorial analysis of the pear jam and technological functions of dehydrated aguamiel are required.

Findings/Conclusions: Pear in advanced stage of maturity could be considered as a good ingredient in jam formulation. Dehydrated aguamiel was used as an alternative a sweetener in jam
ARCHES Digital Twin Framework
Authors: Barbie Alexander
Published: December 2022

In the Helmholtz Future Project ARCHES (Autonomous Robotic Networks to Help Modern Societies) with a consortium of partners from AWI (Alfred- Wegener-Institute Helmholtz Centre for Polar and Marine Research), DLR (German Aerospace Center), KIT (Karlsruhe Institute of Technology), and the GEOMAR (Helmholtz Centre for Ocean Research Kiel), several Digital Twins of ocean observation systems were developed by the GEOMAR and AWI. The ARCHES Digital Twin Framework is one of the results of this project. The software is based on the Robot Operating System (ROS) and is written in Python.
The Influence of Radical Islam on the Quality of Islamic Education in Schools
Authors: Dodego Subhan Hi Ali , Muwafiqoh Arisatul , Hamka Buya , Aminudin Maulana
Published: December 2022

This paper discusses the influence of radical Islamic understanding on the quality of Islamic education in schools. The method used in this research is qualitative. While the data collection technique is literature. The results of this study indicate that. First, the notion of radicalism in Islam is an understanding that wants radical changes in both the individual, social, political and religious domains. The understanding of religious radicalism wants a fast and revolutionary change by using exclusive, extreme, fundamentalist methods and finally terrorizing opponents who do not agree with them. Interpreting the verses of the Qur’an and hadith is done textually and according to their wishes. Second, currently the influence of radicalism has targeted and entered into Islamic education in schools. The survey results of several institutions indicate that the influence of radicalism and intolerance is included in the realm of Islamic education. The influence of radical understanding in the world of Islamic education today is through various ways, it could be from the teachers, the learning curriculum in schools, learning methods, textbooks to the inclusion of mass media platforms. Third, deradicalization of radicalism in Islamic education needs to be done to ward off radicalism, such as parents and the community jointly preventing the rise of cases of radicalism in the world of education.
THE ROLE OF EUROPEAN PRACTICES OF THE YOUTH POLICY IMPLEMENTATION IN THE FORMATION OF YOUNG POLITICAL ELITE IN UKRAINE
Authors:   SSI «Institute of education content modernization», Daragan Tetiana , Vlasyuk Oksana ,   SSI «Institute of education content modernization»
Published: December 2022

The article is devoted to the study of the organization of student self-government in two European countries, such as France and England. The relevance of the study is due to the need to analyze and thus introduce the best experience of leading universities in Western Europe on the functioning of student unions. Student activity in European HEIs is aimed not only at obtaining high-quality higher education but also at active social and public activities. As a result, in various unions, students acquire primary skills in organizing election companies and acquire the basics of management and political experience. The article reveals that the activities of student self-government in France are mainly reflected in the work of the various student unions. Students should be elected and work in councils of students and, therefore, gain experience in electoral campaigns. Student unions are politically oriented, and their members have certain political preferences, but they do not openly support any political party. Student union activity in England is characterized by excessive politicization, which is a consequence of the history of its establishment. Hence, all forms of political life in England are reflected in the activities of student unions. Through their activities, student unions seek to involve more young people in public life. For this, seminars and conferences are held, various manuals are printed and different projects are implemented. Financial support for the work of student councils not only creates good conditions for their activities but also requires justification for the use of funds and is constantly monitored. Thus, students acquire the skills of correct and balanced use of finance and timely reporting on expenditures. According to the results of the study, the authors found that the experience of student government in France and England is essential for the development of student democracy in Ukraine, as well as for determining the form of youth involvement in social and political life (both within their community and within the state). Prospects for further research include an analysis of the impact of the activities of student self-government bodies of Ukrainian HEIs on the formation of the civic position of youth, as well as the development of a new political elite of the country.
HUMAN CAPITAL DEVELOPMENT ACCORDING THE NATIONAL ECONOMIC STRATEGY OF UKRAINE UNTIL 2030
Authors:   Institute of Economics and Forecasting of the National Academy of Sciences of Ukraine, Agafonova Mariia
Published: December 2022

The aim of the article is to identify ways to win the competition for talents, outlined in the National Economic Strategy of Ukraine until 2030. The article analyzes the level of education and training in Ukraine, the level of skills and competencies available in the country, as well as the level of competitiveness of national talents based on the World Digital Competitiveness Report (WDCR) 2021/IMD, World Talent Ranking (WTR) 2021/IMD and Global Innovation Index 2021/WIPO. Despite the fact that from year to year the level of education and training in Ukraine shows a growing trend (in 2021 according to the WDCR Ukraine was included in the TOP-20 countries, for the first time since 2016 occupying 18th position among 64 countries of the world), the level of competitiveness of national talents is weakening (in 2021 the country weakened its position, taking 46th place among 64 countries against 42nd place in 2020). In this regard, the basic barriers to increasing the competitiveness of national talents and winning competition for them have been identified. The first of them is the ability to retain local talents in Ukraine, attracted, in particular, from the International Talent Pool (according to this indicator, our country occupies the penultimate position, even though according to the WTR 2020, the International Talent Pool is approached by those economies that are at the top of the world talent rankings). The second barrier is the motivating factor (by the level of «brain drain», Ukraine ranked among the top three outsiders in 2021, despite the fact that according to the WTR 2021, the world's most competitive economies in the field of talent are the best employee motivation, similar to education indicators). The last obstacle on the way to increasing the competitiveness of national talents is the level of scientific concentration in the country, which since 2018 shows a declining trend (according to this indicator during 2018-2021, our country lost 15 positions). Recom­mendations for increasing the level of competitiveness of national talents are given and the ways to win the competition for talents are outlined.
MODERN METHODS OF DEVELOPING FINANCIAL LITERACY AMONG THE UKRAINIAN CITIZENS
Authors:   Odesa National Economic University, Dombrovska Sofiia
Published: December 2022

The presented work describes the urgency and necessity of the formation of financial literacy among the population of Ukraine. The importance of financial literacy formation among the youth of the country is substantiated, especially it is necessary for higher education seekers, which are potential carriers and future transmitters of knowledge and skills to the next generation. The essence and significance of financial literacy of a person are analyzed, and its main characteristics and features are described. The analysis of statistical information on the main components of the Financial Literacy Index of the Organization for Economic Cooperation and Development of the population of Ukraine was conducted based on such factors as age, sex, level of education and place of residence (city or village). It is established that the category of the young population of Ukraine needs knowledge and skills in financial literacy and rational financial behavior the most. The preconditions of the low level of the Financial Literacy Index of the young population of Ukraine are described. The main reasons for financial illiteracy are the lack of information, knowledge and skills on financial literacy acquired in the family and educational institutions. The article justifies the significance and importance of integration of financial literacy in the form of an educational component for applicants in HEIs. The role and place of a teacher in HEIs for the development of financial literacy among students are described. The main conceptual, methodological and practical problems and contradictions of the introduction of financial literacy in the cognitive process of HEI students are presented. The main recommendations and proposals for improving the level of financial literacy of applicants for higher education in Ukraine are given. Current and innovative methods and ways allowing to improve the level of financial literacy of seekers of higher education in modern socio-economic conditions were highlighted.
AXIOLOGICAL ASPECT OF SPIRITUAL DEVELOPMENT OF PEDAGOGICAL STAFF
Authors:   Borys Grinchenko Kyiv University, Shkirenko Olena
Published: December 2022

The article reflects an axiological aspect of the development of the spirituality of participants in pedagogical interaction. Scientific works are analyzed on the study of objective factors that actualize the problem of the development of values and spirituality. The purpose of the article is to study the level of spirituality, potential and values of teachers, to determine the psychological characteristics of the formation of spiritual and moral values of teachers, and to determine the axiological aspect of personal development. According to the purpose of our study, we used a system of valid psychodiagnostic techniques (observations, interviews, questionnaires, test methods, sociometric data of fellow teachers), as well as a group of data processing methods (qualitative and quantitative analysis, determination of correlations). It’s concluded that the initial level of the development of teachers’ spiritual values is 21,8 %, the spirituality of teachers is 193 %, and the spiritual potential of teachers is 17,5 %. It means that almost a quarter of teachers with an initial level of spiritual development often focus on individualistic values. They are characterized by weak self-control, impulsiveness, low level of empathy and moral norms, unmotivated sense of rivalry, increased antisocial activity (intrigue, rebellion), violation of the hierarchy of motives and values and spiritual regulation, and inability to higher spiritual qualities. They want to deepen the theoretical and practical levels of spirituality, but, unfortunately, do not make adequate efforts for self-development. Educators with an average level of development of spiritual values, spirituality and spiritual potential do not always possess the stability and consistency of the value system of personality, but they adequately assess their qualities of character, level of development of culture and values, and can identify their shortcomings, etc. Teachers with sufficient and higher levels of development of spiritual values, spirituality and spiritual potential can effectively solve spiritual and moral problems and professional tasks of the educational process. They consciously try to acquire spiritual and moral knowledge and update professional values in their own activities. According to the results of statistical processing, the development of teachers' values correlates directly with the focus on altruism. Having a willingness to give up their interests for the good of others, and developed self-awareness, and responsibility, teachers work on the development of spirituality. We see the prospect of further research in the in-depth study of the interaction of participants in pedagogical interaction, modification and improvement of development programs, and development of innovative technologies that would contribute to the formation and develop­ment of axiological aspects of a person’s spirituality.
Family-Based Optimization Intervention Implemented through Video-Conferencing to Address Major Depressive Disorder in a Latina Adolescent Athlete During COVID-19
Authors: Phrathep Davy , Brad Donohue  , Daniel Allen
Published: December 2022

Major Depressive Disorder is a highly prevalent mental health concern impacting adolescent athletes in unique ways (McGuine et al., 2021), yet sport-specific interventions for adolescent athletes with this disorder have yet to be formally developed. The Optimum Performance Program in Sports (TOPPS) is a sport-specific evidence-supported intervention that has successfully treated depression in collegiate athletes (Donohue et al., 2018). However, evidence for this approach in youth athletes has yet to be established. Further, COVID-19 has shifted the delivery of traditional mental health services to video conferencing (Boelen, 2020), yet very few clinical trials have examined evidence-based intervention implementation in this format. This study reports the results of a case involving an adolescent girl who was formally assessed with Major Depressive Disorder. Study results indicated significant improvements from baseline to post-treatment in the severity of general mental health symptoms, depression, factors interfering with sport performance, and relationships with family, coaches, and teammates. Treatment protocol adherence was excellent, and she was highly satisfied with treatment implementation.
Penggunaan Kalimah Allah Oleh Penganut Kristian Di Malaysia Menurut Maslahah
Authors: Lokman Nur Wahida , Nor Amir Husin Mohd , Gunardi Setiyawan
Published: December 2022

Konflik telah berlarutan antara masyarakat Islam dan masyarakat Kristian di Malaysia apabila pada 2021, rakyat Malaysia dikejutkan dengan keputusan Mahkamah Tinggi Kuala Lumpur yang memutuskan bahawa penganut agama Kristian boleh menggunakan kalimah Allah dan tiga perkataan lain iaitu solat, Kaabah dan Baitullah dalam penerbitan agama itu dan untuk pendidikan dalam komuniti mereka selain daripada konflik yang telah berlaku pada 2003 dahulu. Ini menyebabkan masyarakat Islam merasa tidak berpuas hati serta menunjukkan bahawa masih tiada jalan penyelesaian yang kukuh bagi masalah tersebut. Oleh itu, kajian ini dijalankan untuk menerangkan maksud kalimah Allah dari segi istilah kamus Arab, kamus Melayu dan menurut penganut Kristian. Kajian ini juga akan mengemukakan jenis-jenis maslahah serta menyimpulkan kewajaran penggunaan kalimah tersebut dibenar pakai kepada penganut Kristian di Malaysia menurut kaca mata maslahah. Kajian ini menggunakan kaedah kepustakaan daripada sumber primer dan sekunder serta analisis data. Hasil daripada kajian mendapati bahawa kewajaran penggunaan kalimah Allah oleh orang bukan Islam di Malaysia adalah tergolong daripada jenis Maslahah Mulghoh, maslahah yang tidak diiktiraf oleh syara’.
MRSA carriage among healthcare workers in a Vietnamese intensive care unit: a prospective cohort study
Authors: Duong Thuy B. , Duong Minh C. , Campbell James I. , Nguyen Hoang V.M. , Nguyen Hien H. , Bui Hanh T.B. , Nguyen Chau V.V. , Heywood Anita
Published: December 2022

Background: Little is known about the magnitude and patterns of methicillin-resistant Staphylococcus aureus (MRSA) carriage among intensive care unit (ICU) healthcare workers (HCWs), especially in lower-middle-income countries like Vietnam.
Materials and methods: A prospective cohort study was conducted on HCWs working in the adult ICU of the Hospital for Tropical Diseases in Vietnam between October 28 and December 20, 2019. These HCWs included physicians, nurses, and nursing assistants who were responsible for all essential medical activities and basic patient care. A questionnaire was used to collect participants’ information, including age, sex, profession, ICU working time, and underlying diseases. Hand and nasal swabs were collected weekly for 8 consecutive weeks for MRSA screening. Staphylococcal isolates were checked for catalase and coagulase and, for methicillin resistance using cefoxitin disk diffusion, then rechecked on the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Results: Among 55 HCWs, 16 (29.1%) carried MRSA in their noses or hands. MRSA intermittent hand carriage was documented in 2 (3.6%) HCWs. Among 53 HCWs undertaking nasal swabs, 13 (24.5%) were MRSA persistent and 3 (5.6%) were intermittent carriers. The MRSA carriage rate was highest among nursing assistants (50%, 4/8). More HCWs with underlying diseases were found to be MRSA carriers (31.8%, 7/22) compared with those without comorbidities (27.3%, 9/33).
Conclusion: MRSA carriage among HCWs is not rare. The findings highlight an urgent need to review and update the local infection prevention and control measures to prevent MRSA transmission from HCWs to patients.
DECISION SUPPORT SYSTEM OF REWARDING ON LECTURER PERFORMANCE USING FUZZY TSUKAMOTO METHOD CASE STUDY AT MATARAM UNIVERSITY OF TECHNOLOGY
Authors: Yani Ahmad , Zenuddin Z , Hambali H , Muslim Rudi , Imran Bahtiar
Published: December 2022

To prepare quality and character human resources, Mataram Technological University strives to provide the best in carrying out the tridharma activities of higher education, one of which is by giving rewards in the hope that morale and loyalty can continue to be improved. However, the gift-giving system that the Mataram Technological University has implemented has not been able to bring about change because the gift-giving system is incorrect. This is because the applied reward-giving assessment system only refers to the assessment without paying attention to other criteria in the tridharma of higher education. Such as the implementation of learning, Research, and community service. Therefore, to overcome this problem, a decision support information system for awarding lecturer performance is needed, which is built using the fuzzy Tsukamoto method by considering several criteria such as Presence, Research Results, and Community Service Results. Lecturer Performance Index in carrying out the learning process. With this decision support system, the implementation of the Tridharma carried out by lecturers can continue to monitor the system and improve the quality and accreditation of study programs and universities.
Pembiasaan Literasi Numerasi dan Hasil Belajar Matematika Kelas V MI Giwangretno
Authors: Oktaviana Dewi , Murtopo Bahrun Ali , Chamidi Agus Salim
Published: December 2022

The purpose of this study was to determine the refraction of numeracy literacy for class V, mathematics learning outcomes for class V, and whether there is a relationship between numeracy literacy habituation and mathematics learning outcomes for class V MI. Sruweng Giwangretno The quantitative research method was used in this research, with the correlation method. As the research sample, 45 students from class V participated in this study. The data for this study came from numeracy literacy questionnaires and math story test questions given to class V students. The habituation of numeracy literacy in class V reached a criterion level of 91 %. The test results show the results of mathematics learning for class V students. The test results for learning mathematics for class V students show that the criteria level is good, 57.78 %. At a 5% significance level, the results of rxy = 0.41 are greater than r table = 0.2940 based on the product moment correlation test. This shows that the alternative hypothesis has been accepted. Based on the data analysis, it is possible to conclude that the habit of numeracy literacy has a relationship with it and affects students' mathematics learning outcomes.
GAMBARAN GRIT PADA MAHASISWA YANG MEMILIKI ONLINE SHOP
Authors:   Universitas Katolik Widya Mandala Surabaya Indonesia, Dharmawan Albertus Suhardinata
Published: December 2022

Technological advances make everything fast so, there are many changes in various sectors including the industrial sector. The process of buying and selling transactions can now be done digitally and online. This progress is used by college students to get income to meet their needs. The problem that arises when students have an online shop is how the lecture process and the business online shop run optimally? Grit is a combination of consistency with passion, namely consistency with goals that have been set for a long period of time, and perseverance which means the ability to overcome the desire to give up (Duckworth, 2016). Grit is one of the differences so that online shops and lectures can run together and optimally. Researchers conducted research to determine the description of grit in college students who have an online shop. This research used a qualitative approach with a phenomenological type. The data obtained were analyzed using themethod led theory, especially deductive analysis. The research informants were undergraduate students with a minimum GPA of 2.75 and theage was online shop over 1 year. The results of the study found that the grit of the two informants was the same as the existing theory. There are 4 aspects, namely 1) interest, 2) practice, 3) purpose, and 4) hope that there are also factors that influence the growth of grit, namely 1) parenting, 2) culture and 3) experience. However, researchers found another factor, which is the situation where informants were forced to be independent because students had to migrate away from their parents.
STRES AKADEMIK DAN DUKUNGAN TEMAN PADA MAHASISWA TAHUN PERTAMA SELAMA PEMBELAJARAN DARING
Authors:   Universitas Katolik Widya Mandala Surabaya Indonesia, Putro Alessandro Widianto , Simanjuntak Ermida ,   Universitas Katolik Widya Mandala Surabaya Indonesia
Published: December 2022

Pandemi Covid-19 yang terjadi di Indonesia menyebabkan Kementrian Pendidikan dan Kebudayaan mengeluarkan peraturan untuk melaksanakan pembelajaran secara daring bagi mahasiswa di Perguruan Tinggi. Mahasiswa tahun pertama sebagai mahasiswa yang baru saja mengalami masa transisi dari SMA menuju Perguruan Tinggi merupakan pihak yang rentan mengalami stres akademik saat pembelajaran daring. Stres akademik adalah respon yang dirasakan oleh tubuh terkait tuntutan yang tinggi dari dunia akademik. Beberapa penelitian menunjukkan bahwa stres akademik dapat menurun ketika individu memperoleh dukungan dari lingkungan sekitarnya. Pada penelitian ini dukungan dari lingkungan sekitar adalah dukungan yang diberikan oleh teman. Penelitian ini bertujuan untuk menguji hubungan antara dukungan teman dan stres akademik pada mahasiswa tahun pertama selama pembelajaran daring. Responden dalam penelitian ini berjumlah 194 mahasiswa tahun pertama yaitu 66 mahasiswa dan 128 mahasiswi. Hasil penelitian menunjukkan ada hubungan yang signifikan antara dukungan teman dengan stres akademik pada mahasiswa tahun pertama selama pembelajaran daring (r = -0,356; p<0,05). Mahasiswa tahun pertama yang memperoleh dukungan dari teman akan menurun stres akademik yang dirasakannya. Dosen disarankan dapat menyediakan metode pembelajaran yang memberikan kesempatan pada mahasiswa untuk bekerjasama secara interaktif sehingga mahasiswa memperoleh dukungan dari teman mahasiswa selama proses pembelajaran daring.
Food allergy management in daily life: accidental allergic reactions, cofactors and adherence to dietary advice
Authors:   , Versluis Astrid
Published: December 2022

Food allergy is caused by an IgE-mediated immune response to allergenic proteins in a food. It manifests by symptoms of the skin, mucous membranes, gastrointestinal tract, respiratory tract and/or cardiovascular system. The severity of the symptoms varies per patient and per food from only mild itching in the mouth, to sometimes life-threatening and fatal reactions, by for example, blocking of the airways or a drop in blood pressure and shock. The key interventions after diagnosing a food allergy are prescribing an elimination diet and emergency medication to treat accidental allergic reactions. Despite specific dietary advice and the support given, accidental reactions to food still occur in the daily life of food allergic individuals.
The aim of this thesis was to gain more insight into: 1) the frequency, severity and impact on costs and quality of life of accidental allergic reactions to food, 2) which factors play a role in the occurrence of these reactions, and 3) the degree to which dietary advice is followed after ruling out or confirming a food allergy and which factors play a role in the degree of adherence to dietary advice.
This thesis showed that accidental allergic reactions occur frequently in the daily lives of adults with food allergy, often causing severe symptoms. These reactions have a significant impact on direct and indirect costs. The occurrence of accidental allergic reactions is affected by many factors, related to the patient, health care and food. Important patient-related factors are age, social barriers to the disclosure of their allergy (e.g. in restaurants) and non-adherence to the elimination diet. Not every factor applies for every individual patient. With regard to health care-related factors, the degree to which clinical practice is tailored to the individual patients is important. A major food-related factor is absence of harmonized regulation regarding precautionary allergen labelling (e.g. ‘’may contain peanuts’’). Furthermore, non-adherence to dietary advice frequently appears both after ruling out and confirming a food allergy. It is highly recommended to tailor health care even more to the individual patient, for example with regard to education and support of behavioral and psychosocial aspects. Furthermore, it is of great importance that steps are taken to improve policies and guidelines for precautionary allergen labelling.
Effective and sustainable patient participation
Authors:   , Noordhoek-van der Staaij Jacqueline Jeannette
Published: December 2022

This thesis focuses on how the Dutch CF Foundation defined the patients’ perspective as a starting point for the improvement of quality of care and the making of a patient prioritized research agenda. Quality of care and can be improved if we take into account the patients’ perspective in a structured way. Professional and systematical involvement of patient representatives in the development of standards of care for example, paves the way for useful insights, that contribute to a golden standard if merged with the expertise of medical experts. Quality of care also improves when criteria are defined that are meaningful to the people with CF. CF centers of expertise were assessed systematically based on criteria defined by patients themselves. The program is feasible and manageable for a professional patient organization to run, and showed a high efficacy. The results of the assessment show that quality of care improves when the using the patients’ perspective in the procedure. The patient organization is also able to address specific issues with regard to people with CF, offering them early intervention if a certain problem occurs (coaching project). This program is highly effective.
The process to close the gap between the patients’ unmet needs and outcomes of relevant research is described. A wide range of conditions has been laid bare, in order to set up a patient prioritized research agenda. Acting in the best interest of the patient is no longer the ultimate task of clinicians, but also of researchers
Role of Genetic Variations in Determining Treatment Outcome in Head and Neck Cancer
Authors: Ruwali Munindra
Published: December 2022

Worldwide, head and neck squamous cell carcinoma (HNSCC) is responsible for >550,000 diagnoses and 380,000 deaths annually. It originates in the upper aerodigestive tract and has a multifactorial origin involving both genetic and lifestyle risk factors. The clinical management of HNSCC involves surgery, radiotherapy, and chemotherapy. Several studies point to the role of genetic variations in predicting drug efficacy and toxicity. Cancer pharmacogenomics has fast emerged as a new and promising field for the early identification of genetic markers that can predict drug response or toxicity, with the number of studies of genetic polymorphisms as prognostic factors of HNSCC treatment outcomes growing. The number of studies evaluating the association of candidate polymorphisms in drug-metabolising Phase I and II enzymes with treatment outcome far exceed the studies involving other candidate genes, such as those involved in drug metabolism, DNA repair, and cell cycle regulation. This review focusses on the relevance of genetic variations in genes, where the corresponding gene products play an important role in drug metabolism (TPMT, DPD), DNA repair (X-ray repair cross complementing 1), cell cycle (tumour protein P53), and carcinogenesis (matrix metalloproteinase 3 and 7), thereby contributing to the treatment outcome for HNSCC. This could greatly help clinicians in identifying genetic markers useful for the selection of optimal drugs, dose, and treatment duration on an individual basis, resulting in improved drug efficacy and decreased toxicity. However, further studies are needed in well characterised and larger HNSCC populations with proper validation of pharmacogenetic markers in experimental settings before application in clinical routine diagnostics.
Morphology-syntax mismatches in agreement systems: The case of Jóola Fóoñi
Authors: Hofherr Patricia Cabredo , Creissels Denis
Published: December 2022

The present study examines the agreement system of Jóola Fóoñi (Atlantic, Niger-Congo). In Niger-Congo languages, noun forms divide into subsets according to their agreement patterns. The morphological paradigm of the agreement targets is generally analysed as a reflex of agreement triggered by nominal controllers. For Jóola Fóoñi this view is not correct since (i) the range of subsets of noun forms and the range of values on the agreement targets do not match and (ii) inflection for a subset of class values is associated with its own semantic and syntactic properties, independent of agreement configurations with nouns. In Jóola Fóoñi the classification of noun forms based on their agreement properties and the cells of the inflectional paradigm of adnominal and pronominal agreement targets are related but independent components of the grammar. Of the 15 class-values that structure the inflectional paradigm of adnominals and pronouns involved in the expression of agreement with heads or antecedents, only 13 class-values function as agreement values with nominal controllers; the other 2 class-values only appear on agreement targets. The inflectional paradigm characterising agreeing adnominals and pronouns is heterogeneous in several respects. (i) Of the 15 class-values in the inflectional paradigm, only 12 allow non-contextual uses without a nominal controller, each associated with a particular meaning. (ii) Non-contextual uses of the 5 class-values expressing time, manner and different conceptualizations of space display adverbial syntax, while the other class-values show pronominal syntax. (iii) Of the 5 class-values associated with adverbial syntax, the 3 locative classes differ from the classes associated with time and manner with respect to relativisation. We propose that the forms inflected for class that express place, time or manner in their non-contextual use have become adverbs, and the locative relativisers have been reanalysed as locative relative pronouns.
Identifying Success Factors, Deciding On Methodology and Implementation of Project Portfolio Systems: A Hybrid, Two-Layer Solution in TurkStat
Authors: METİN Furkan , GÜL Nesibe , YILDIRIM VURAL Müge Naz
Published: December 2022

Purpose: In order to manage projects to achieve strategic goals and targets with limited resources, portfolio-project management (PPM) systems become increasingly popular tools for large organizations. Nevertheless, due to various reasons such as lack of financial resources, awareness of the significance of portfolio management many organizations do not have a software system that can keep up with the projects. The purpose of this paper is to share The experience gained within three years during the establishment of an effective and inexpensive PPM system to manage organisational projects. Design/methodology/approach: In this study, several project management tools are compared to understand what features of these tools meet the needs of Project Management Institute (PMI) knowledge areas. Afterwards, a hybrid, two-layer portfolio management tool developed in the Turkish Statistical Institute (TurkStat) is introduced. The first layer is built on Redmine, an open-source tool, and its purchasable plugins. The second layer is an in-house developed software application which uses the application programming interfaces (APIs) of Redmine. Findings: This needs-oriented, less costly hybrid system has yielded remarkably successful results in planning, leading, monitoring and controlling processes of projects under the knowledge areas of PMI. Limitations: Besides the advantages of the system, some knowledge area activities still cannot be managed by the hybrid system like quality management and procurement management. Originality: The two-layer approach can be an example of the best practice solution for other organisations with limited resources as well.
Pemberdayaan Pelaku Seni Jaranan Nganjuk Dalam Menangani Cidera Melalui Keterampilan Masase Terapi
Authors: Sifa Agus , Hariyanto Agus , Suryandoko Welly
Published: December 2022

Pengabdian Kepada Masyarakat  yang berjudul Pemberdayaan Pelaku Seni Jaranan Nganjuk Dalam Menangani Cidera Melalui Keterampilan Masase Terapi  memiliki tujuan mendasar penerapan  pada  masyarakat  yaitu  mensejahterahkan    dengan  selalu  menjaga kesehatan dengan cara menjaga kondisi fisik. Para pelaku Jaranan perlu diperdayakan agar taraf hidup dan daya hidup lebih baik. Maka, melalui pengabdian ini dapat memberikan kontribusi yang baik, sebab tujuan utama dilaksanakan pengabdian ini adalah agar pelaku dapat mandiri dalam mengatasi cidera ringan maupun cidera berat pada saat atau setelah pertunjukan. Pemberdayaan dilakukan dalam bentuk 1) Keterlibatan mitra sebagai peserta pelatihan masase terapi pada cidera, 2) Terlibat dalam penanganan cidera melalui keterampilan masase terapi, 3) Melibatkan pelaku Jaranan lainnya untuk diberdayakan agar memiliki keterampilan masase terapi, 5) Keterlibatan dalam membentuk kelompok masase terapi untuk para pelaku Jaranan. Tujuan utamanya agar pelaku Seni Jaranan memahami manfat, teknik dan praktik masase terapi ini. Berikutnya adalah dengan memberikan legitimasi untuk pelaku Jaranan yang mahir melakukan masase terapi berupa sertifikasi bahwa pelaku Seni Jaranan masing-masing telah memiliki keterampilan dalam menangani pemain Jaranan saat mengalami cidera.
Kata kunci: Seni Jaranan; Cidera; Masase Terapi
Transfigurasi Komunikasi Visual pada Corak Motif Batik Pamekasan Madura
Authors: Triandika Lulus , Dewi Danar Kristiana
Published: December 2022

Sebagai warisan budaya, Batik Madura memiliki nilai sejarah dan filosofi yang mendalam. Kabupaten Pamekasan sebagai daerah penghasil batik di Madura senantiasa mempertahankan corak motifnya secara turun-temurun selama ratusan tahun. Namun pengaruh perkembangan kondisi sosial dan budaya ternyata memberikan pengaruh pada batik Pamekasan. Terutama pada corak motifnya, secara umum Batik Pamekasan menggunakan figur tumbuhan dan binatang dalam corak motifnya. Namun, secara detail pengaruh perkembangan sosial dan budaya terlihat dalam corak motif batik Pamekasan. Termasuk pengaruh figur selain tumbuhan dan binatang yang menjadi inspirasi pembuatan corak motif batik.   Corak motif batik menarik untuk dikaji sebagai sebuah produk    

     budaya yang seharusnya mempertahankan tata aturan leluhur. Meskipun telah banyak kajian tentang batik, namun masih sedikit tentang corak motif dalam batik. Terlebih kajian tentang corak motif batik Pamekasan Madura dari perspektif komunikasi visual. Sehingga menarik untuk dikaji lebih dalam guna mengetahui perkembangan dalam corak motif batik Pamekasan. Penelitian ini menggunakan metode diskriptif kualitatif, dengan teknik pengumpulan data melalui observasi, studi literatur, dan hasil wawancara dengan narasumber. Analisis Semiotika visual Charles Sanders Peirce dipakai guna mengkaji objek penelitian yakni corak motif batik. Kemudian diambil kesimpulan berdasar analisis data.
Möjligheter med STEM-undervisning genom robotik i förskolan
Authors: Fridberg Marie , Cronquist Björn , Redfors Andreas
Published: December 2022

I takt med att digitalisering, teknik och naturvetenskap fått en alltmer framskjuten plats i europeiska läroplaner för yngre barn har frågor väckts hos förskollärare och lärare i länderna om vad detta innebär för undervisningen. Som en följd skapades botSTEM-projektet (2017-2020), ett Erasmus+-projekt med samarbetspartners i Spanien, Sverige, Italien och Cypern. Syftet var att skapa och erbjuda förskollärare och lärare en verktygslåda i form av en interaktiv hemsida med exempel på undervisningsaktiviteter som kombinerar naturvetenskap, teknik, ingenjörskunskap, matematik och robotik för barn fyra-åtta år gamla, där lärarna kan hämta inspiration och också utbyta erfarenheter med varandra. I den här artikeln beskriver vi förskollärarnas arbete med naturvetenskap och robotik i botSTEM och de forskningsresultat, om undervisningsstrategier och kommunikation mellan lärare och barn, som projektet ledde fram till.
PEGylation and folic-acid functionalization of cationic lipoplexes—Improved nucleic acid transfer into cancer cells
Authors: Hoffmann Marco , Gerlach Sven , Hoffmann Christina , Richter Nathalie , Hersch Nils , Csiszár Agnes , Merkel Rudolf , Hoffmann Bernd
Published: December 2022

Efficient and reliable transfer of nucleic acids for therapy applications is a major challenge. Stabilization of lipo- and polyplexes has already been successfully achieved by PEGylation. This modification reduces the interaction with serum proteins and thus prevents the lipoplexes from being cleared by the reticuloendothelial system. Problematically, this stabilization of lipoplexes simultaneously leads to reduced transfer efficiencies compared to non-PEGylated complexes. However, this reduction in transfer efficiency can be used to advantage since additional modification of PEGylated lipoplexes with functional groups enables improved selective transfer into target cells. Cancer cells overexpress folate receptors because of a significantly increased need of folate due to high cell proliferation rates. Thus, additional folate functionalization of PEGylated lipoplexes improves uptake into cancer cells. We demonstrate herein that NHS coupling chemistries can be used to modify two commercially available transfection reagents (Fuse-It-DNA and Lipofectamine® 3000) with NHS-PEG-folate for increased uptake of nucleic acids into cancer cells. Lipoplex characterization and functional analysis in cultures of cancer- and healthy cells clearly demonstrate that functionalization of PEGylated lipoplexes offers a promising method to generate efficient, stable and selective nucleic acid transfer systems.
A hybrid system for the overproduction of complex ergot alkaloid chanoclavine
Authors: Ma Yaqing , Yan Juzhang , Yang Lujia , Yao Yongpeng , Wang Luoyi , Gao Shu-Shan , Cui Chengsen
Published: December 2022

Synthetic biology-based methods (Sbio) and chemical synthesis (Csyn) are two independent approaches that are both widely used for synthesizing biomolecules. In the current study, two systems were combined for the overproduction of chanoclavine (CC), a structurally complex ergot alkaloid. The whole synthetic pathway for CC was split into three sections: enzymatic synthesis of 4-Br-Trp (4-Bromo-trptophan) using cell-lysate catalysis (CLC), chemical synthesis of prechanoclavine (PCC) from 4-Br-Trp, and overproduction CC from PCC using a whole-cell catalysis (WCC) platform. The final titer of the CC is over 3 g/L in this Sbio-Csyn hybrid system, the highest yield reported so far, to the best of our knowledge. The development of such a combined route could potentially avoid the limitations of both Sbio and Csyn systems and boost the overproduction of complex natural products.
Digital technologies and data-driven delay management process for construction projects
Authors: Radman Kambiz , Jelodar Mostafa Babaeian , Lovreglio Ruggiero , Ghazizadeh Eghbal , Wilkinson Suzanne
Published: December 2022

One of the main challenges of construction projects is managing delays; there is still a lot to overcome to reach near-zero delays (mitigation of delays) in all construction projects. Technology and different platforms are applied to support a high volume of data flow acquired from multiple resources during the construction project life cycle; how can these automated and digital progress tracking systems be considered for more effective construction delay management? The aim is to investigate the current state of real-time technologies and their applications and assess how specific attributes of these disruptive technologies can significantly alter delay management in construction industries. Therefore, this study presents a new process-based framework for using technologies with a data lifecycle viewpoint. This research uses a four-step systematic literature review involving identification, screening, extortion-eligibility check, and selection-inclusion. Furthermore, it is followed up by a thematic content analysis on using new technologies to mitigate delays in construction projects. Key trends, themes, areas of concern for research, and limitations identified in previous literature as research gaps and future needs were documented and structured. This work presents a novel process of comprehensive classification of real-time technologies that are being used in the construction industry to acquire data, screen/analyses data, and present information through an Industry 4.0 application: IoT technologies such as sensors, RFID etc., smartphones, planning/scheduling tools (Ms Project, Primavera), and Building Information Modelling (BIM). The developed process-based framework is served as a roadmap to 1) centralise real-time communication between technologies to collect, analysis and presentation data in construction phase, 2) prepare timely reports for project managers to take proper action against those problems delaying project.