bluuebunny/crossref_metadata_2025 huggingface dataset:
ORGANIZATION AND IMPLEMENTATION OF PROJECTS IN THE FIELD OF MARINE CARGO TRANSPORTATION ON THE EXAMPLE OF “VOLGOTRANS” COMPANY
Authors: Прокопенко Анастасия Александровна
Published: September 2024

В данной статье рассматривается современное состояние отрасли морских грузоперевозок в России, а также организация и реализация проектов в сфере морских грузоперевозок на примере компании ООО «Волготранс».

This article examines the current state of the maritime cargo transportation industry in Russia, as well as the organization and implementation of projects in the field of maritime cargo transportation using the example of Volgotrans company.
THE ROLE OF THE ASSESSMENT SYSTEM IN GAME-BASED LEARNING
Authors: Кругликов Виктор Николаевич
Published: September 2024

В статье на основе анализа методических разработок начинающих преподавателей-аспирантов, рассматривается роль системы оценивания в обучающих играх. Рассматриваются типичные ошибки начинающих преподавателей в вопросах постановки целей игры. Дается трактовка понятия двуплановости игры и обоснование приоритета дидактических целей.

The article, based on an analysis of the methodological developments of novice postgraduate teachers, examines the role of the assessment system in educational games. The typical mistakes of novice teachers in setting game goals are considered. An interpretation of the concept of a two-dimensional game and a justification for the priority of didactic goals is given.
Multimaterialstrukturen für die Medizintechnik/Multi-material structures for medical devices
Authors: Springer Patrick , Sonnentag Tobias , Echsel Markus
Published: September 2024

Stereotaxierahmen sind Instrumente für neurochirurgische Eingriffe und sollen zukünftig aus Kunststoffen aufgebaut werden. Um derartige Systeme, die jährlich in kleinen Stückzahlen benötigt werden, wirtschaftlich herstellen zu können, wurde untersucht, wie sich Bauteile mittels Multimaterial-Hochleistungsthermoplasten aus gefüllten und ungefüllten Polyetherimiden additiv fertigen lassen. Der Fokus der Untersuchung lag auf der Analyse und Optimierung der Verbundfestigkeit gedruckter Multimaterialstrukturen.
Flexible, leitfähige Strukturen mit Laserschweißen/Flexible, conductive structures by laser welding – Continuous joining of metallic foils with thermoplastic textiles
Authors: Boich Robert T. , Hannes Neele , Brackmann Friederike
Published: September 2024

Die Textilindustrie steht im Bereich „Wearable Technologies“ vor Herausforderungen. Bestehende Verfahren zur Herstellung leitfähiger Verbindungen auf Textilien zeigen Schwächen. Eine vielversprechende Lösung ist das Lasertransmissionsschweißen. Um dieses Verfahren auf einen kontinuierlichen Rolle-zu-Rolle-Prozess zu übertragen, wird ein Maschinenkonzept entwickelt. Dieses wird in einer Testreihe mit dem Ziel, das Verfahren in eine bestehende Rolle-zu-Rolle-Anlage zu integrieren, validiert.
Die Treiber der Fahrzeug- und Zulieferindustrie/Process technology trends and drivers in the vehicle and supplier industry – The drivers of the vehicle and supplier industry
Authors: Uhlmann Eckart , Polte Mitchel , Marquardt Josephine , Fielers Marie-Noelle , Senyüz Onur
Published: September 2024

Die Fahrzeug- und Zulieferindustrie steht durch technologische, verbraucherspezifische und regulatorische Anforderungen vor einem tiefgreifenden Wandel. Um ihre Wettbewerbsfähigkeit in diesem dynamischen Umfeld zu erhalten, müssen Unternehmen sich kontinuierlich anpassen. In diesem Beitrag werden daher die Trends und Treiber dieser Transformation identifiziert. Zudem werden Schlüsselfaktoren vorgestellt, die für eine transformationsbeständige und wandlungsresistente Produktion entscheidend sind.
Laserkontaktieren von Vierfachkupferflachdrähten/Laser contacting of quadruple copper flat wires – Optimized winding topologies for hairpin technology
Authors: Merz David , Schabel Sebastian , Fleischer Jürgen , Schmid Laurens
Published: September 2024

Die Hairpin-Technologie, häufig verwendet in der Produktion elektrischer Traktionsmotoren, zeigt bei hohen Drehzahlen deutliche Effizienznachteile aufgrund von Skin- und Proximityeffekten. Im Rahmen des Verbundforschungsprojekts KontaktE wird der Laserkontaktierprozess innovativer Wicklungstopologien und Leitertechnologien untersucht und optimiert. Diese Studie präsentiert die Ergebnisse experimenteller Untersuchungen zur Identifikation idealer Parameterfenster für das Laserkontaktieren von Vierfachschweißungen.
Sprachverständlichkeitstest mit direktanzeigenden Messgeräten/Speech intelligibility test with direct-display measuring devices
Authors: Veit Ivar
Published: September 2024

Mit der Entwicklung von Sprachverständlichkeitstests wurde bereits vor über 80 Jahren begonnen, und zwar ursprünglich für die Bedürfnisse der Fernsprechtechnik. Dort ging es zunächst darum, die Güte von elektroakus- tischen Übertragungsanlagen und -strecken zu testen. Als Indikator dafür galt die messtechnisch zu ermittelnde Verständlichkeit von übertragener Sprache, und zwar zunächst nur durch Normalhörende [1]. Solche Prüfungen wurden in den Folgejahren weiterentwickelt, und zwar zur Prüfung des noch verbliebenen Hörvermögens von Personen mit Hörbeeinträchtigungen [2].
Gefährdungen bei der Mensch-Maschine-Interaktion
Authors: Spatz Johannes , Langstrof Alexandra
Published: September 2024

Der Umgang mit Maschinen ist wesentlicher Bestandteil in vielen Berufen. Während diese früher vor allem über Schalter, Hebel, Lenkräder und Tasten gesteuert wurden, treten Menschen heute zunehmend über sogenannte Benutzerschnittstellen mit den Maschinen in Kontakt. Da immer mehr Daten verschiedener Sensoren miteinander kombiniert werden, um die Vorgänge optimal zu erfassen und zu steuern, führt dies zu einer größer werdenden Komplexität und damit verbunden auch zu neuen Gefährdungen. Technische oder funktionale Lösungen allein genügen häufig nicht, um Unfälle zu vermeiden. Welche Maßnahmen sich in der Praxis eignen, erfahren Sie in diesem Beitrag.
Der neue Entwurf der Richtlinie VDI 3783 Blatt 1/The new draft of the guideline VDI 3783 sheet 1
Authors: Schalau Bernd
Published: September 2024

Im November 2019 wurde der Entwurf der VDI-Richtlinie 3783 Blatt 1 „Ausbreitung von störungsbedingten Freisetzungen“ als Gründruck veröffentlicht. Neben den Einsprüchen zur Richtlinie in Bezug auf unklare Formulierungen, wurde oft das Fehlen eines Referenzprogramms, als auch die Abkehr vom etablierten Gauß-Wolken-Modell bemängelt. Im Rahmen der darauffolgenden Überarbeitung des Richtlinienentwurfs wurde ein Gauß-Wolken-Modell entwickelt, das mit einem geringen Rechenaufwand in einem begrenzten Anwendungsbereich mit dem Lagrange’schen Partikelmodell vergleichbare Berechnungsergebnisse liefert. Darüber hinaus wurden Empfehlungen zur praktischen Umsetzung von Szenarien in den neuen Richtlinienentwurf, der voraussichtlich im Oktober 2024 als Gründruck vorliegt, aufgenommen.
Mit offenem Visier
Authors: Konersmann Rainer
Published: September 2024

Vor 30 Jahren, am 28. September 1994, sank die Ro/Pax-Fähre Estonia. Es war der folgenschwerste Schiffsuntergang, den die Ostsee in Friedenszeiten erlebt hat. Die Untersuchungen zur Ursache nahmen Jahre in Anspruch. Selbst heutzutage gibt es noch Zweifel und verschiedene, teils irritierende, Interpretationen zum Ereignisablauf. Aber wenn man die Fakten sortiert und die Hintergründe im Blick behält, war die Katastrophe eigentlich keine große Überraschung.
ANALYSIS OF THE EXPERIENCE OF CIVIL SOCIETY INSTITUTIONS IN MOTHER AND CHILD HEALTH PROTECTION
Authors:   Independent researcher, Uzbekistan, Nigora Kutlimurotova
Published: September 2024

This article is dedicated to the comparative study of maternal and child health protection policy, it briefly covers the practices of our country and the world, and it defines the main directions for the future. An attempt was made to reveal the role and role of civil society institutions in maternal and child health protection through real numbers and their analysis.
EVALUATING MACHINE LEARNING ALGORITHMS FOR BREAST CANCER DETECTION: A STUDY ON ACCURACY AND PREDICTIVE PERFORMANCE
Authors:   College of Graduate and Professional Studies Trine University, USA, Al-Imran Md , Akter Salma ,   Department of Public Administration, Gannon University, Erie, PA, USA, Mozumder Md Abu Sufian ,   College of Business, Westcliff University, Irvine, California, USA, Bhuiyan Rowsan Jahan ,   Master of Science in Information Technology, Washington University of Science and Technology, USA, Rafi Md Al ,   Master of Science in Information Technology, Washington University of Science and Technology, USA, Bhuiyan Md Shahriar Mahmud ,   Master of Science in Information Technology, Washington University of Science and Technology, USA, Rodrigues Gourab Nicholas ,   Master of Science in Information Technology, Washington University of Science and Technology, USA, Mir Md Nazmul Hossain ,   Master of Science in Information Technology, Washington University of Science and Technology, USA, Hasan Md Amit ,   Master of Science in Information Technology, Washington University of Science and Technology, USA, Das Ashim Chandra ,   Master of Science in Information Technology, Washington University of Science and Technology, USA, Hossen Md. Emran ,   Department of Science in Biomedical Engineering, Gannon University, USA
Published: September 2024

This study evaluates several machine learning algorithms—Support Vector Machine (SVM), Random Forest, Logistic Regression, Decision Tree (C4.5), and k-Nearest Neighbors (KNN)—for breast cancer detection using the Breast Cancer Wisconsin Diagnostic dataset. We implemented comprehensive pre-processing and model evaluation with Scikit-learn in Python. Our findings show that SVM achieved the highest accuracy, with 99.9% on the training set and 98.50% on the testing set, indicating superior performance in handling high-dimensional data. Random Forest also performed well, with accuracies of 98.5% and 98.20%, respectively. Logistic Regression and Decision Tree models provided reliable predictions when tuned, while KNN was less effective. SVM and Random Forest are recommended for clinical decision support systems due to their high accuracy and robustness.
Entwicklung einer Fortbildungsstruktur zum Einsatz digitaler Medien im Mathematikunterricht – ein Werkstattbericht
Authors: Dilling Frederik , Holten Kathrin , Hörnberger Kevin , Schneider Rebecca , Witzke Ingo
Published: September 2024

Der vorliegende Werkstattbericht stellt die Fortbildungsstruktur im Projekt DigiMath4Edu zum Einsatz digitaler Medien im Mathematikunterricht dar. Diese basiert auf zwei Säulen: Die erste Säule beinhaltet verschiedene Formate an Fortbildungsveranstaltungen von einer Fortbildungsreihe, über zentrale Fortbildungstage bis hin zu Miniworkshops an Schulen. In der zweiten Säule findet eine von Lehrer:innen durchgeführte und von Student:innen begleitete Erprobung der Medien im Unterricht statt.
Kegelschnitte erkunden - genetisch, ganzheitlich, dynamisch, anschaulich
Authors: Elschenbroich Hans-Jürgen
Published: September 2024

Kegelschnitte sind ein enorm reichhaltiges Thema, aber dennoch weitgehend aus dem Kanon der Schulmathematik verschwunden. Hier wird mit dem digitalen Werkzeug GeoGebra 3D ein ganzheitlicher und genetischer Weg vorgeschlagen, zum einen die vielfältigen Aspekte zu verbinden und zum anderen mit Hilfe der Prinzipien systematische Variation und dynamische Visualisierung zumindest in Ansätzen spiralig unterrichtbar zu machen.
Auswahl und Nutzung von Erklärvideos im Mathematikunterricht - eine Annäherung aus verschiedenen Perspektiven der Praxis und der Theorie
Authors: Knippers Matthias
Published: September 2024

In der aktuellen (deutschen) empirische Unterrichtsforschung zeigt sich ein breites Bild an Einsatzmöglichkeiten von Erklärvideos. Unklar bleibt: Welche Kriterien für eine sinnvolle Erklärvideonutzung gibt es? Was muss jemand tun, um ein mathematisches Erklärvideo passend zu den eigenen Bedürfnissen auszuwählen? Fokussiert wird in diesem Beitrag auf die Nutzung von Erklärvideos durch Lernende selbst im Zeitraum einer Klassenarbeit. Unter Beachtung von Häufigkeit und Selbstbestimmtheit der Nutzung sollen Nutzungsmuster exploriert werden.
Es zählt der Prozess: Planen, Modellieren, 3D-Drucken und TPACK
Authors: Läufer Tim , Ludwig Matthias
Published: September 2024

3D-Druck wird in der Bildung vielversprechend eingesetzt und auch in der Bildungsforschung häufig thematisiert, es fehlt aber (Weiter-)Bildung für Lehrkräfte. Gerade Manipulatives bieten für Lehrkräfte viele reichhaltige Möglichkeiten, die mit dem 3D-Drucker realisiert werden können. Wir stellen in diesem Beitrag unsere Forschungsidee und Methode zur Untersuchung des 3D-Modellierungs- und Druckprozesses zur Erstellung von Manipulatives vor.
Erlernen der Ableitung über dynamische Visualisierungen per se besser als über statische? – Ergebnisse aus einer Pilotierungsstudie
Authors: Nguyen Hoang
Published: September 2024

Im Rahmen dieser Studie wurden die Zugänge zur Ableitung über ausschließlich dynamische oder statische Visualisierungen im Zwei-Gruppen Prä-Post-Design mit 110 Lernenden (Klasse 10 bzw. 11) verglichen. Es zeigte sich, dass beide Gruppen im Durchschnitt ihre Leistung verbesserten, jedoch kein signifikanter Interaktionseffekt zwischen der Visualisierungsart und den Messzeitpunkten besteht; auch waren Grundvorstellungen zur Ableitung ähnlich stark ausgeprägt.
Individuelle Unterstützung von Primarschulkindern beim Lösen von Zahlenmaueraufgaben mithilfe eines intelligenten Tutors
Authors: Rüeger Philipp , Kruschwitz Jessica , Schmalfeldt Thomas
Published: September 2024

Im vorliegenden Entwicklungsprojekt bearbeiteten Schüler*innen der 2. Primarklasse im Rahmen eines leitfadengestützten Interviews Zahlenmaueraufgaben in einem intelligenten Tutorsystem und wurden gebeten, Rückmeldungen zum Tutor zu geben. Es wurde untersucht, ob die Nutzendenoberfläche, die Rückmeldungen, Hilfestellungen und Symbole umfasste, von den Schüler*innen in der intendierten Weise interpretiert und bedient werden konnte.
Vorbereitung auf die digitale Arbeitswelt im regulären Mathematikunterricht? Der 3D-Druck als authentischer Lernkontext aus Sicht von Unternehmen
Authors: Wulff Mira , Heinze Aiso
Published: September 2024

Der 3D-Druck gewinnt in der Arbeitswelt zunehmend an Relevanz. Für einen erfolgreichen Übergang in Berufe, die diese Technologie nutzen, sind Informationen über die von Unternehmensseite erwarteten Kenntnisse relevant. In einer Interviewstudie mit 15 Repräsentant:innen verschiedener Branchen wurden Erwartungen zu 3D-Druck-bezogenen Kenntnissen sowie Einbindungsmöglichkeiten in den regulären Fachunterricht herausgearbeitet.
Desempeño Docente y la Gamificación en Matemática en Estudiantes con Bajo Rendimiento en la Educación General Básica
Authors: Garcia Carrillo Mariana de Jesus , Bernal Párraga Augusto Paolo , Alexis Cruz Gaibor Wladimir , Cruz Roca Anthony Brayan , Ruiz Vasco Dany Eduardo , Montaño Ordóñez Janeth Alexandra , Illescas Zaruma Mery Sulay
Published: September 2024

El desempeño de los docentes juega un papel fundamental en la alfabetización matemática, especialmente para los estudiantes con bajo desempeño en la educación general introductoria. Esta composición investiga cómo las prácticas de tutoría y la calidad de la tutoría afectan el buen desempeño de estos académicos. A través de una revisión total de la literatura y el análisis de estudios de caso en varias instituciones educativas, se examinan las estrategias pedagógicas que utilizan los preceptores para mejorar el desempeño de los escolares con dificultades en matemáticas. La exploración destaca la importancia de la capacitación continua y de los preceptores en metodologías de tutoría efectivas. Los resultados muestran que los docentes que participan en programas de desarrollo profesional y que aplican formas innovadoras de tutoría, similares a la alfabetización basada en problemas y el uso de arcas tecnológicas, logran mejores resultados en el desempeño de sus alumnos. Estas estrategias no sólo ayudan a aclarar generalidades complejas y finas, sino que también fomentan un terreno de alfabetización más interactivo y motivador. Otro aspecto crítico vinculado es la relación entre el maestro y el alumno. Los estudios muestran que un terreno probatorio y de confianza, donde los académicos se sienten valorados y comprendidos, contribuye significativamente a mejorar el rendimiento académico. Los docentes que adoptan un enfoque centrado en el alumno muestran empatía y adaptan su tutoría a los requisitos individuales, tienen más éxito a la hora de perfeccionar el desempeño de los académicos de bajo rendimiento en matemáticas. Además, el uso de evaluaciones constructivas y retroalimentación continua es esencial para cubrir el progreso de los alumnos. Las prácticas de evaluación que brindan información detallada sobre áreas de mejora y éxitos ayudan a los estudiantes a comprender sus fortalezas y habilidades, y a los preceptores aclimatar sus estrategias de tutoría en consecuencia. Aun así, la perpetración de estas prácticas enfrenta desafíos, incluida la falta de arcas aceptables, la carga de trabajo de los preceptores y la necesidad de apoyo institucional. Es fundamental que los programas educativos prioricen la formación del profesorado escolar y den los fondos necesarios para aplicar prácticas tutorías efectivas. En conclusión, el desempeño docente tiene un impacto significativo en la alfabetización matemática de los estudiantes con bajo desempeño en la educación general básica. A través de la capacitación continua, el uso de metodologías innovadoras y un enfoque centrado en el estudiante, los docentes pueden mejorar significativamente el rendimiento académico. El apoyo institucional y los recursos adecuados son cruciales para la implementación exitosa de estas estrategias.
ASSOCIATION OF TNFAIP3 AND CDS1 GENES POLYMORPHISM WITH BACK FAT THICKNESS IN PIGS
Authors:   Federal Research Center for Animal Husbandry named after Academy Member L.K. Ernst, ROMANENKOVA O.S. , VOLKOVA V.V. ,   Federal Research Center for Animal Husbandry named after Academy Member L.K. Ernst, BELOUS A.A. ,   Federal Research Center for Animal Husbandry named after Academy Member L.K. Ernst, RESHETNIKOVA A.A. ,   Federal Research Center for Animal Husbandry named after Academy Member L.K. Ernst
Published: September 2024

The back fat thickness is an important characteristic that affects the quality of meat. Molecular genetic studies have made it possible to identify a number of genes associated with indicators of back fat thickness, intramuscular fat content, precocity, body length and average daily gain. Genome-wide association studies (GWAS) have shown that TNFα-induced protein 3 (TNFAIP3) and CDP-diacylglycerol synthase 1 (CDS1) genes are associated with back fat thickness. We conducted the study of two polymorphisms TNFAIP3 (rs81351586, A/G) and CDS1 (rs331818788, C/A). The experimental sample included 195 Large White sows and 161 Landrace sows. Determination of polymorphisms was carried out through RT-PCR. The frequencies of occurrence of alleles and genotypes were established. The study revealed a significant difference between the backfat thickness at the withers and the backfat thickness above the 6–7 thoracic vertebrae for the CDS1 gene in Landrace pigs. There were no significant differences in the TNFAIP3 gene between individuals with different genotypes.
Texto para Discussão 3036
Authors: Monteiro Neto Aristides
Published: September 2024

Este texto para discussão tem como objetivo discutir a validade e as oportunidades possíveis para a realização da tarefa de coordenação de políticas produtivas no território. Procura dialogar diretamente com as preocupações nacionais de desenvolvimento territorial equitativo e, desse modo, com a Política Nacional de Desenvolvimento Regional (PNDR). Avalia a trajetória recente dos mais relevantes instrumentos de financiamento produtivo com impactos territoriais, quais sejam, a política de crédito rural; os desembolsos do Banco Nacional de Desenvolvimento Econômico e Social (BNDES) para atividades produtivas; os valores aplicados dos fundos constitucionais de financiamento (FCFs) da política regional; e a capacidade governamental de atuar por meio do gasto federal em investimento público. Como resultado da investigação, o trabalho mostra elevada concentração de recursos de financiamento em regiões mais desenvolvidas e pouco afeitas, atualmente, ao patrocínio do pacto redistributivo nacional para uma sociedade justa.
Effects of Neem Tree Leaf Extract (Azadirachta I Ndica A. Juss) as Defaunating Agent of Sheep (Ovis Aries L.) Fed Napier Grass (Pennisetum Purpureum Schumach)
Authors: Capin Valleser Arnold , Dela Cruz Caraca Dolly Ann
Published: September 2024

The effectiveness of neem tree leaf extract (NTLE) as defaunating agent was compared with sodium lauryl sulphate (SLS). Ten (10) sheep was used in the comparison of defaunating agents, the neem tree leaf extract was found to cause fluctuations in ruminal pH, similar to that of sodium lauryl sulphate, effectively reducing protozoal counts (from 296,000 cells/ml to 1,000 cells/ml) and increasing bacterial population (from 10,780 colony forming units/ml to 950,000 colony forming units /ml) in the rumen of sheep. It is therefore strongly advised to use neem tree extract as defaunating agents for sheep fed Napier grass to defaunated sheep in order to maximize food utilization and animal performance.
Lunasin: A Medicinally Important Chemo-Preventive Natural Dietary Pe
Authors: Singh Jaspreet , Singh Amandeep
Published: September 2024

Lunasin is a natural peptide of plant origin possessing potential activity against chronic disorders specially cancer along with associated cardiovascular diseases. The bioavailability and confirmed effectiveness against breast, skin and colorectal cancer has declared lunasin as a promising chemo-preventive agent. Lunasin, a 43 amino acids long peptide possess anti-inflammatory and anti-oxidative activity. Modern biotechnological techniques viz. genomics, proteomics along with other biochemical tools are continuously elucidating the molecular mechanisms of lunacin action. Lunasin enriched natural product-based healthcare remedies for the prevention of life style induced cancer is suggested as an alternative to the conventional chemo, immuno and hormonal therapy.
Factors Influencing the Success Criteria of ICT Project Management Case Study Constructions in Mogadishu
Authors: Ilyas Ali Zahra , Isak Abdirahman Mohamed Adam
Published: September 2024

Being a developing nation, our nation's project construction is advanced in comparison to earlier years. Therefore, the overall goal of this study is to evaluate and examine the local elements influencing the success criteria of ICT project management in the construction sectors. The purpose of this study is to evaluate the technical factors that affect the success of ICT project management in the Somali construction industry. To determine the organizational factors that affect the ICT project management success in the Somali construction industry. And to investigate the cultural factors that affect the success of ICT project management in the construction industry. The most recent study to look at environmental factors influencing the performance of ICT project management in the Somali construction industry. The report focuses on construction initiatives completed in Somalia's capital city of Mogadishu. Both interviews and questionnaires were used to gather the data. The questionnaire was completed online using Google Form, and the respondents were clients, consultants, and contractors. The researchers used practical sampling to gather 100 surveys. There are four case study companies that I have chosen as an experiment construction companies are utilized as a case study for this research project. The data from the questionnaires were analyzed using SPSS to produce the average index from the study; Dalbile construction and contracting company, Bile home repair and Construction service, Qidmad Construction Company and Gaabow Construction Company. Due to the growing technological uncertainty, the building sector is dynamic. Building projects are getting easier and more advanced today. The coordination between the project participants is what has an impact on how well construction projects execute when using the design build method of procurement. The Somali government should establish and enforce strict penalties to combat fraudulence activities, the licensing of contractors and consultants should be thoroughly scrutinized to ensure that they are qualified and have the tools necessary to perform their jobs, and the contractors should enhance their estimation methods and take into account all external factors that could affect their projects.
Method Development and Validation of Assay of Rilpivirine in Rilpivirine Tablets by RP-HPLC
Authors: N Shriya. , Rani S. Shobha , M Karthik. , Reddy Y. Sridhar , Naseeruddin Mohammad
Published: September 2024

A method was developed and validated for determining the Assay of Rilpivirine in Rilpivirine Tablets by using WATERS HPLC 2695 with Autosampler, PDA Detector and Empower 3 Software. ACE Excel 3 C18 AR (250 x 4.6 mm, 3 μm) column was used along with a mobile phase combination Acetate Buffer: Methanol: Acetonitrile in ratio 60: 30: 10 % v/v/v. Isocratic flow with flowrate of 1.5 mL/minute, Injection volume 12 mL was employed. Column temperature of 30°C was maintained. Detection wave length of Rilpivirine was 258 nm. Run time was optimised to 5 min based on retention time. The retention time of Rilpivirine was 2.29 minutes. The method was found to be specific, linear with a square of correlation coefficient (R2 ) 1.000, accurate over the concentration range of 25 % to 200 %, precise with % RSD of six samples 1.1 and robust. Thus a simple, quick and economical method was developed and validated.
Jól időzített intézkedés
Authors: Fázsi László
Published: September 2024

The author uses a specific case in Hungary to demonstrate the importance of timing in police action.
Munka és büntetés. A közérdekű munkáról és a fogvatartottak munkáltatásáról
Authors: Pap Júlia
Published: September 2024

The author provides an overview of the Hungarian penal law by showing the advantages and disadvantages of employing a convict during a prison sentence or as an alternative punishment.
Fiatalkorú fogvatartottak a börtönben: kognitív- és kriminálpszichológiai megfontolások
Authors: Fliegauf Gergely
Published: September 2024

The author provides an overview of some of the challenges the new, 2013 Hungarian prison code poses for experts working with juvenile prisoners. Special emphasis is given to changing brain capacity, newly discovered specialities of adolescence, moral conflict, long sentence, identification with perpetrator and victim, prison rape, suicide, self harm and benzodiazepine abuse.
Katonai és biztonsági magánvállalatok külföldi tevékenysége: szabályozási kérdések
Authors: Déry Kinga
Published: September 2024

The author provides a comprehensive overview of the international, national and self-regulation of the activities of private military and security companies, the ways in which the concerned approaches complement each other, the gaps related to the implementation of the relevant instruments, the issues related to responsibilities for violations of the law, as well as the related work of the UN’s Working Group on the Use of Mercenaries.
Development of Intelligent Help System for Small Cities
Authors: Khan Nayyar Ahmed , Ahmed Mohammad , Hamdaoui Rim , Uddin Siddiqi Ahmed Masih , Khalid Mohammad Nadeem
Published: September 2024

It is a common observation that. Once, while travelling to a city unknown to you, you sometimes find it challenging to get help from various places where it is required. The need for markets, food, pharmacies, medicines, hospitals, workshops, and other goods requires a proper guide that can be available quickly. Specific software like maps helps a lot but cannot provide the information needed for a particular point in time. Also, they are not concerned and maybe connected with the direct service provider. Thus, finding the person worried about this work becomes tricky. Also, it is tough for the maps to provide the exact information required at a particular location. Thus, there must be a remedy for this specific problem. The system we will design in this context supports the availability of all kinds of necessary services. The services are required occasionally and then by various people who will visit the city for a new time. The project aims to develop an application to help users who have been entering a particular city for the first time and would require specific services. The services are available to users who have already registered and are working in the system. The services offered by a particular user in the system shall be made available easily with the help of those concerned who are going to help.
A Monograph on Anatomy and Variants of Hepatic Resectional Surgery
Authors: Coco Danilo , Leanza Silvana , Viola Massimo Giuseppe
Published: September 2024

BACKGROUND: The liver anatomy appears to be very complex due to the enormous number of vascular and biliary branches as well as the fact that the underlying pathology frequently distorts the anatomy. To prevent damage during surgical or invasive procedures, it is advised to be aware of the arteries’ typical structure and variations. Hepatic surgeons, general surgeons, transplant surgeons, interventional radiologists, and other medical specialists who treat liver problems must have this knowledge.
MATERIALS AND METHODS: We have retrospectively evaluated the PubMed databases, Embase, and the Cochrane Library by applying various combinations of subject-related terms. The search terms identified with the medical subject heading were “Anatomy, right hepatectomy, resection, variants.” The databases were used to collect the literature published since 1991.
RESULTS: Results delineated that 91.6% of patients had a single right hepatic vein, 81% shared a trunk with their middle hepatic vein (MHV) and left hepatic vein (LHV), and 19% had separate MHV and LHV drainage into the inferior vena cava. Overall prevalences of the abnormal hepatic artery, abnormal right hepatic artery (aRHA), abnormal left hepatic artery (aLHA), and combined aRHA/aLHA were found to be 27.41%, 15.63%, 16.32%, and 4.53%, respectively. The most common variation (type 2) is the so-called “portal vein (PV) trifurcation,” in which the main PV divides into the left PV, the right anterior PV, and the right posterior PV. The right posterior sectoral duct joins the left hepatic duct with a supraportal course, the right posterior sectoral duct joins the right anterior sectoral duct with an infraportal course, the trifurcation variation of the biliary tree, retroportal course, and the left lateral segmental ducts caudal to the umbilical portion of the PV are examples of variant biliary anatomy encountered in PV variations. Duplication of the common bile duct is a very uncommon congenital biliary system defect.
CONCLUSION: It is very crucial for surgeon to have abreast knowledge of the tributaries, their anatomy, and variations to limit blood loss and operative morbidities.
Surgical treatment after augmentation mammoplasty with polyacrylamide hydrogel
Authors: Sukhotko Anna , Covantsev Serghei , Bumbu Anna , Kovaleva Maria , Zakurdaev Evgenii
Published: September 2024

Polyacrylamide hydrogel mammoplasty is a simple and relatively affordable surgery. However, this procedure is associated with a significant frequency of late complications, prompting its suspension in 2006. Despite this, patients continue facing long-term consequences. These include hydrogel migration, changes in breast shape and volume, granulomas, fistulas, and abscess formation. The clinical case described here presents the surgical treatment after augmentation mammoplasty with polyacrylamide hydrogel performed 35 years ago.
Syphilis among Roma community: a single-center experience in Bulgaria (socio-demographic data collection, 2008–2022)
Authors: Gospodinov Dimitar , Gospodinova Klimentina , Haidudova Hristina
Published: September 2024

Introduction: With a population of roughly 11 million, the Roma (Gypsies) are the largest ethnic minority in Europe, particularly in the countries of Central and Eastern Europe. A number of serious socioeconomic issues, such as poor health, low levels of education, unemployment, discrimination, criminal activity, high-risk sexual behavior, and a high rate of illnesses, including STDs, are present in their society.

Aim: This study set out to investigate the frequency and demographics of syphilis within the Pleven region’s Roma population.

Materials and methods: The methodology pertains to the study of data obtained from the Pleven registrations of the University Clinic of Dermatology and Venereology. The patients were chosen between the years 2008 and 2022.

Results: The findings demonstrated that over the course of the study’s 15 years, 323 people fell ill, with 35% of those individuals being Roma. Simultaneously, the proportion of Roma people living in the Pleven region fluctuated between 4.09% in 2011 and 3.09% in 2021. There were 113 Roma patients with syphilis, with 55% being female and 45% being male. The age group most commonly affected was 20–29 years old (44%), followed by singles (32%), and cohabiting individuals (49%), 49% had primary and basic education, 54% were unemployed, and 82% were heterosexual. Among Roma women, 11.5% were prostitutes, 14% were pregnant, and 15% gave birth. Cases of congenital syphilis were 4.4%. Statistically significant differences in all observed characteristics in Roma and patients from other ethnic groups are consistent with the data in other Central and Eastern European countries.

Conclusion: In conclusion, our findings confirm the high risk of contracting syphilis.
Effects of Two Vision Therapy Approaches on Accommodative Insufficiency and Post-therapy Stability
Authors: Manna Prithwis , Karmakar Sourav , Mondal Animesh , Sarbajna Puja , Bhardwaj Gaurav Kumar
Published: September 2024

Purpose

To evaluate the effect of the EYEPORT II vision training system (Bernell) on accommodation in cases of accommodative insufficiency.

Methods

The experimental study was conducted in a binocular vision clinic. Of 230 patients, 36 were eligible and willing to participate in office-based therapy. Participants were randomly divided into two groups: control and EYEPORT. The control group received conventional therapy and the EYEPORT group received conventional therapy combined with the EYEPORT II vision training device. The therapy lasted for 1 hour daily over 6 days in a week, with 24 sessions administered over 4 weeks. Accommodative parameters were reevaluated 2 weeks, 4 weeks, and 3 months after treatment.

Results

The study included 19 men and 17 women, with a median age of 27.50 years. After 24 sessions of vision therapy, accommodative parameters improved significantly, with more pronounced results compared with baseline measurements, as demonstrated by the Wilcoxon signed-rank test (
P
< .05). The Mann–Whitney
U
test indicated a significant (
P
< .05) improvement in treatment outcomes for the EYEPORT group using the EYEPORT device together with conventional therapy. The median accommodation amplitude increased by 6.95 diopters (D), the accommodation lag decreased by −0.25 D, the positive relative accommodation improved by −1.63 D, and the accommodative facility increased by 13 cycles/minute. After 3 months without therapy, the treatment outcome was maintained.

Conclusions

Office-based vision therapy can effectively treat accommodative insufficiency. Both groups showed improvement in the accommodative amplitude and other parameters. The EYEPORT group was more stable at 3 months.

[
J Pediatr Ophthalmol Strabismus
. 2025;62(1):12–26.]
Comparing the Postoperative Outcomes of Intrastromal Corneal Ring Segments in Three Different Topographic Patterns of Eccentric Keratoconus
Authors: Yousif Mohamed Omar , Elkitkat Rania Serag , Elmassry Ahmed , Hamza Mohamed Nabil , Alaarag Noha Abdelsadek
Published: September 2024

Purpose:

To compare the postoperative outcomes following implantation of KERATACx ring segments (Imperial Medical Technologies Europe GmbH) in patients having eccentric keratoconus with three different topographic patterns.

Methods:

This retrospective cohort study was conducted at Maadi Eye Subspeciality Center, Cairo, Egypt. The study included patients with keratoconus who had implantation of KERATACx ring segments. Three groups were segregated based on topographic keratoconus patterns using the Sirius CSO Topographer (CSO Italia): type I ectasia where the cone coincides with the corneal flat axis, type II ectasia in which the cone coincides with neither the steep nor the flat axis and lies between the two axes, and type II ectasia for cones coinciding with the corneal steep axis. The visual and topographic outcomes were compared preoperatively and postoperatively for the three enrolled groups.

Results:

This study enrolled 92 eyes of 92 patients and had a mean ± standard deviation follow-up of 16.9 ± 9.2 months. The patients' medical records revealed that night vision complaints and halos around the light were experienced the most by the type III ectasia group (31.25%). For the type III ectasia group, four topographic indices and one visual parameter did not show statistically significant differences between the preoperative and postoperative data (inferior-superior difference at 2- and 4-mm diameter, coma aberration, higher order aberrations, and uncorrected distance visual acuity), contrary to the type I and II ectasia groups, which showed significant improvements in all evaluated parameters.

Conclusions:

The type III morphological pattern of ectasia is the least likely to benefit from KERATACx ring segments implantation.

[
J Refract Surg
. 2024;40(9):e625–e634.]
Repeatability of a Combined Adaptive Optics Visual Simulator and Hartman-Shack Aberrometer in Pseudophakic Eyes With and Without Previous Corneal Refractive Surgery
Authors: McBee Dylan , Kozhaya Karim , Wang Li , Weikert Mitchell P. , Koch Douglas D.
Published: September 2024

Purpose:

To evaluate the intrasession repeatability of wavefront aberrations obtained by a combined adaptive optics visual simulator and Hartman-Shack aberrometer in pseudophakic eyes with and without previous corneal refractive surgery.

Methods:

Three consecutive measurements were performed in one eye of each individual. Total ocular aberrations were recorded up to the 5th Zernike order for a 4.5-mm pupil. Repeatability was assessed by calculating the within-subject standard deviation (S
w
), the repeatability limit (R), and the intraclass correlation coefficient (ICC). Vector analysis was performed to assess astigmatism variability between scans.

Results:

The study enrolled 32 normal individuals and 24 individuals with a history of refractive surgery. In normal and eyes that had previous refractive surgery, respectively, the S
w
values were 0.155 and 0.176 diopters (D) for sphere and 0.184 and 0.265 D for cylinder. The S
w
values for all 3rd order terms ranged from 0.037 to 0.047 µm in normal eyes and 0.044 to 0.063 µm in eyes that had previous refractive surgery. The S
w
for primary spherical aberration was 0.020 µm in normal eyes and 0.026 µm in eyes that had previous refractive surgery. ICC values for measurements of astigmatism yielded larger variability (ICC = 0.751 and 0.879). However, both groups demonstrated excellent repeatability (ICC > 0.9) for root mean square higher order aberrations (RMS-HOA) and total RMS values.

Conclusions:

In pseudophakic eyes, the adaptive optics Hartmann-Shack device demonstrated acceptable repeatability for measurement of sphere and 3rd and 4th order HOAs with higher variability for astigmatism measurements, especially in eyes with a prior history of corneal refractive surgery.

[
J Refract Surg
. 2024;40(9):e645–e653.]
Influence of Capsular Tension Rings on the IOL–Capsule Complex in Patients With Long Axial Length: A Clinical Observation Based on SS-OCT
Authors: Chang Pingjun , Hu Yiwen , Wu Xueer , Qian Shuyi , Li Yuanyuan , Wang Yiyi , Yang Fuman , Zhao Yune
Published: September 2024

Purpose:

To evaluate the influence of a capsular tension ring (CTR) on the intraocular lens (IOL)–capsule complex after cataract surgery in patients with long axial length.

Methods:

This was a prospective study. Patients underwent phacoemulsification and IOL implantation, with or without CTR implantation. Swept-source optical coherence tomography was performed at 1 day, 1 week, 1 month, and 3 months postoperatively to determine the postoperative aqueous depth (PAD), capsular bend index (CBI), and IOL tilt and decentration. Spherical equivalent values were obtained through subjective refraction and autorefraction. Root mean square was adopted to evaluate the indices listed above.

Results:

Forty-three patients (56 eyes) were included in the study. Generalized estimating equation analysis of PAD showed a statistical difference between groups (
P
= .031). The RMS of the change in PAD was smaller in the CTR group than in the non-CTR group during the 3 months after surgery (
P
= .015). CBI in the CTR group increased more from 1 to 3 months after surgery than that in the non-CTR group (
P
= .025). The RMS of the change in vertical decentration was smaller in the CTR group than in the non-CTR group during the 3-month follow-up (
P
= .009).

Conclusions:

CTR implantation can stabilize the axial position of the IOL within the capsular bag after cataract surgery in patients with long axial length without affecting the refractive stability. The formation of capsular bend may be slightly delayed in the early stage after CTR implantation, but it accelerates from 1 to 3 months after surgery.

[
J Refract Surg
. 2024;40(9):e654–e661.]
Optimal profit-making strategies in stock market with algorithmic trading
Authors: Wang Haoyu , Xie Dejun
Published: September 2024

Machine learning (ML) techniques are being increasingly applied to financial markets for analyzing trends and predicting stock prices. In this study, we compared the price prediction and profit-making performance of various ML algorithms embedded into stock trading strategies. The dataset comprised daily data from the CSI 300 Index of the China stock market spanning approximately 17 years (2006–2023). We incorporated investor sentiment indicators and relevant financial elements as features. Our trained models included support vector machines (SVMs), logistic regression, and random forest. The results show that the SVM model outperforms the others, achieving an impressive 60.52% excess return in backtesting. Furthermore, our research compared standard prediction models (such as LASSO and LSTM) with the proposed approach, providing valuable insights for users selecting ML algorithms in quantitative trading strategies. Ultimately, this work serves as a foundation for informed algorithm choice in future financial applications.
Lessons from the pandemic era: do we need new strategies to improve conservative treatment adherence in adolescent idiopathic scoliosis? A retrospective analysis
Authors: Maccarone Maria Chiara , Barzizza Elena , Contessa Paola , Biancato Alyssa , Caregnato Allegra , Fontana Rosanna , Ceccato Riccardo , Salmaso Luigi , Masiero Stefano
Published: September 2024

This study aims to examine whether the COVID-19 pandemic affected the adherence to conservative AIS treatment. Adolescent Idiopathic Scoliosis (AIS) is characterized by a lateral curvature of the spine of at least 10 degrees. Compliance rates in conservative treatments are influenced by various factors. From a database of AIS patients, we selected 30 AIS patients who were assessed before, during, and after the COVID-19 pandemic. Data regarding Cobb’s angle, brace prescription, prescribed brace wear time, brace wear compliance, and time dedicated to sports activities were collected over a six-year period from January 2018 to December 2023, divided into three 2-year time periods (before, during, and after COVID-19). There was an increased percentage of AIS patients prescribed with a brace during the pandemic. However, no significant differences in Cobb’s angle were observed. Additionally, the prescribed wear time showed a significant decrease from the pre-COVID period to the post-COVID period (p-value = 0.03). Wear compliance exhibited a decreasing trend from pre- to during- and post-COVID-19 periods without reaching statistically significant differences, and the time dedicated to sports statistically significantly decreased. These differences were statistically significant when comparing the pre- vs. post- and pre- vs. during-COVID-19 periods (p-values 0.01, 0.04, respectively). Our study highlights changes in AIS conservative treatment during and after the COVID-19 pandemic. The increase in the number of patients prescribed with a brace during the pandemic, although not supported by an increase in Cobb’s angle, may be attributed to the concerns about regular monitoring during the reduction of rehabilitation services. The observed decreases in brace compliance and involvement in sport activities, which persisted even in the post-pandemic period, emphasizes the lasting impact of the pandemic on AIS management, necessitating innovative approaches to address these ongoing concerns.
An Open Declaration [Openlike Verklaring] concerning the Presbyterian Church government system
Authors: Mathundela Chaka C.
Published: September 2024

The challenge posed by 18th-century rationalism to the 16th-century Reformed doctrine, initiated a trajectory in which Reformed churches assumed the responsibility of preserving the essence of the Reformation. The emergence of the Open Declaration [Openlike Verklaring] as a response to rationalism served as a call to unity and a reaffirmation of adherence to the Presbyterian Church government system established in 1618–1619. The objective of this study was to examine the significant contributions of the Open Declaration to Church Polity [Kerkreg] and the Reformed Churches of South Africa (RCSA)[Gereformeerde Kerke van Suid-Afrika (GKSA)] by focusing on three key elements: the declaration of faith and commitment; the acknowledgement of liturgical practices and ecclesiastical governance; and the plea for unity and ecclesiastical communion [Kerkverband]. Drawing on scholarly literature and relevant church documents, the analysis explores the role of the Open Declaration in shaping the identity and practices of the RCSA/GKSA within the broader context of Reformed church history. As a result of completing this study, it is discovered that the Open Declaration should be interrogated at local level and Article 48 should be read in the light of Article 29. Major assemblies should be understood from the local Church Council, Classis, regional Synod, and General Synod – not only Classis, regional Synod and General Synod.Contribution: The proposed shared understanding of the Open Declaration aims to foster a sense of unity among delegates, emphasising the importance of aligning and binding decisions made by the Church Council, Classis, Regional Synod, and General Synod during meetings. In conclusion, local churches should revisit the Public Declaration, engage in local church dialogues to promote ongoing cooperation, prioritise theological education and training to foster unity, upholding the 16th-century Reformational theology, celebrate Holy Communion in one church building, pursue Alternative Dispute Resolution (ADR), seeking biblical ways to address and resolve conflicts between local churches, and supplementing the mechanism provided by Article 31 of the Church Order.
Aluminum Alloy, Extruded Profiles (2024-T432) 4.4Cu - 1.5Mg - 0.6Mn Annealed, Stretch Formed, Solution Heat Treated and Stress Relieved by Stretching
Authors:   AMS D Nonferrous Alloys Committee
Published: September 2024

This specification covers an aluminum alloy in the form of extruded profiles (shapes) 0.063 to 0.375 inch (1.6 to 10 mm), inclusive, in nominal thickness (see 8.6).
Cable Assemblies, Electrical Power, for Portable Ground Support Test Equipment
Authors:   AGE-3 Aircraft Ground Support Equipment Committee
Published: September 2024

This document defines cables that are used to provide electrical power for U.S. Department of Defense avionics support and test equipment.