bluuebunny/crossref_metadata_2025 huggingface dataset:
KAJIAN ANTROPOLINGUISTIK PERMAINAN TRADISIONAL CIP BALA KA CIP DI KALANGAN ANAK USIA SD/MI
Authors: Fadilah Lailiyatul Nur , Mu'minin Mu'minin
Published: November 2020

Permainan tradisional perlu diteliti lebih jauh karena dari segi teks, ko-teks, dan konteks permainan tradisional mengandung satu nilai budaya yang luhur dan membentuk pribadi anak yang baik dari segi fisik dan mental.Penelitian ini menggunakan pendekatan kualitatif deskriptif dengan teknik wawancara, dan observasi. Data yang digali dalam penelitian ini adalah tentang proses permainan, analisis teks, koteks, dankonteks permainan, dan kelebihan permainan tradisional Cip Bala Ka Cip.Hasil dari penelitian ini adalah bahwa secara teks terdiri dari kalimat Cip Bala Ka Cip  yang diucapkan pada awal permainan permainan berlangsung. Ko-teks dengan penekanan pada suku kata “cip”, dan konteks dengan dilakukannya permainan ini di suasana santai dan saat bermain dengan teman sebaya baik di sekolah maupun di rumah. fungsiCip Bala Ka Cip adalah sebagai bentuk hiburan, alat pendidikan anak, alat pemaksa berlakunya norma-norma sosial dan pengendali social, dan sebagai penguat ikatan pertemanan.
Hannibal’s Elephants and the Liburnians
Authors: Bulić Nada , Glavan Maria Mariola , Nečas Hraste Daniel
Published: November 2020

The second Punic war is a relatively well-known episode from Roman
history. Reliable, detailed ancient sources such as Livy and Polybius,
however, don’t say much on the topic of Hannibal’s provisions from
his native Carthage. One of the questions related to the provisions is
where Hannibal’s elephants came from after the battle of Cannae, as
after traversing the Etrurian swamp Hannibal only had one elephant
left (Livy XXII 2). Immediately after the victory at Cannae Hannibal
sends a delegation requesting logistics and the Carthaginian senate
decides to send him military aid, among which were 4000 Numidians
and 40 elephants (Livy XXIII 11-13). In the meantime, Hannibal penetrates
Campania already accompanied by elephants at the Siege of
Casilinum (Livy XXIII 18).
The authors of this paper believe that Hannibal’s path to Cannae
was part of a premeditated military plan, according to which the
Carthaginian army needed to pick up supplies near Cannae, with the
Liburnians playing an important role in opening channels of communication
and supplies. Several facts support this theory, most importantly
the following:
– one of the few suitable ports that Hannibal could count upon to
be less guarded by the Romans than more northern ports, such
as Ariminum, is found near Cannae;
– an enormous amount of money from Africa is in circulation in
Liburnia right at the time of the war with Hannibal;
It is known that political entities on the eastern coast of the Adriatic
had an anti-Roman political agenda during the time of the second
Punic war, coordinating themselves with Macedonia among others,
which became an ally of Hannibal and with which Rome went to war
in 214 B.C, with which the two Illyrian wars right before and right after
the war with Hannibal are related. The authors believe that the sources
point to a sort of coalition for transport, trade and communication
between Hannibal, the Liburnians and Carthage, which should be
viewed in the context of the operations of the anti-Roman coalition
of political entities on the eastern shores of the Adriatic
Ovidio e le ambiguità dell'Eneide
Authors: Fernandelli Marco
Published: November 2020

L'ambiguità è un tratto caratteristico del linguaggio epico virgiliano.
L'idea che essa sia l'espressione di un dualismo tra piani di significato
rappresentati da voci (“Two voices theory'), cui attribuire un grado
maggiore o minore di autenticità, è stata superata a favore di una lettura
che riconosce tale autenticità nello stato aperto del testo, che insieme
stimola all'interpretazione e si presta a una continua riattualizzazione
dei propri significati. L'“ambivalenza” (del testo) ha preso il posto della
dialettica di “ottimismo” e “pessimismo” (nella visione dell'autore).
Virgilio, in Ovidio, è onnipresente. Le ambiguità dell'Eneide, la cui tipologia
è varia, causano, in Ovidio, due risposte: lo invitano a illuminare
le zone contraddittorie di quel testo già classico; oppure sono risolte o
neutralizzate nel quadro di riscritture di genere e intonazione diversi,
ma sempre in modo che la disambiguazione risulti palese e si configuri
come una scelta conforme ai valori di una poetica nuova. Ciò si nota in
particolare nelle Metamorfosi, dove i luoghi più complessi dell'Eneide
nutrono l'invenzione poetica, mentre la loro conversione in situazioni,
immagini, espressioni univoche asseconda la fluidità che il poema del
continuo mutamento richiede al suo linguaggio. Ma questa semplificazione
del complesso e determinazione dell'indeterminato è anche il
filtro attraverso il quale l'inimitabile Eneide si offre all'imitazione delle
generazioni successive.
Rediscovering the Greeks
Authors: Joksimović Milena
Published: November 2020

The article explores the impact of Byzantines on Istrian Humanism
and Renaissance. In the introduction author describes the alienation
of the territories which used to be Eastern and Western part of the
Roman Empire and, congruently, the fate of the classical (particularly
Greek) heritage in the Dark and Middle Ages in those territories.
This is followed by a description of the historical events that led to
rapprochement of the East and West, with particular emphasis on the
Byzantine exodus to Italy. The author then provides a methodological
framework by analyzing the main aspects of „rediscovering” Greek
cultural heritage and the influence of the Byzantine immigrants on
them. The author than turns to Istria, providing, first, a short summary
of Istrian contacts with the Greek cultural heritage throughout history
and then the settlement of the Byzantines in Istria. The main part of the
article follows, containing a detailed analysis of the described elements
of „rediscovering” Greek cultural heritage – interest in Greek language,
literature, culture and philosophy (particularly Neoplatonism), in
translations, the editing and publishing of Greek classics, as well as in
the presence of the idea of a common European identity based on a
common ancient heritage, and the voices advocating for the formation
of a united Christian European front against the Ottomans.
Perspectivas epidemiológicas, fisiopatológicas e clínicas da doença reumática cardíaca: Uma revisão bibliográfica
Authors: Oliveira Igor de Sousa , Melchiori Bianca Ridolfi , Figueiredo Camila Ângelo Vidal de , Silva Gabriel Ferreira da , Parente Igor Sousa e Silva , Muniz Ingrid Silveira Farias , Macedo Rafaela Melo , Sarmento Tiago Gomes , Santos Walberth Gabriel Cardoso dos , Vasconcelos Gilberto Loiola de
Published: November 2020

Objetivos: Compreender e correlacionar as perspectivas epidemiológicas, fisiopatológicas e clínica com o diagnóstico precoce e o bom prognóstico do paciente acometido pela Doença Reumática Cardíaca. Metodologia: Trata-se de uma revisão bibliográfica do tipo integrativa, de caráter retrospectivo, com abordagem qualitativa, elucidando a descrição e a aplicação de estudos nacionais e internacionais. Tal estudo ocorreu nos meses de agosto e setembro de 2020 por meio da base de dados PubMed e seus sites aliados. Para isso, associaram-se os operadores boleanos com os descritores selecionados e pertinentes no corpo de trabalho, por meio da base Medical Subject Headings (MeSH), sendo eles: “cardiopatia reumática”, “febre reumática” e “complicações”. Incluíram-se artigos disponíveis na integra, com recorte temporal dos últimos cinco anos e nos idioma espanhol, inglês e português. Selecionaram-se treze artigos para análise de dados concomitantes com os objetivos da pesquisa. Principais Resultados: Constatou-se com o devido estudo que a Doença Reumática Cardíaca caracteriza-se por seu caráter crônico latente e pouco observado pela sociedade, sendo, desse modo, uma das patologias de maior prevalência entre as complicações da Febre Reumática. Além disso, está correlacionada, diretamente, com os pormenores do sistema imunológico individual, caracterizando um caráter deficitário diante do avanço da doença. Nessa questão e com tais elucidações, ficou claro que reconhecer as repercussões clínicas prevalentes é essencial, a exemplo da Fibrilação Atrial, seguida Insuficiência Cardíaca e acometimento valvar, destacando-se o acometimentos valvar do tipo aórtico como a repercussão mais prejudicial ao prognóstico do paciente. Conclusão: Logo, notou-se com tais questões que os avanços e reconhecimentos das correlações epidemiológicas, fisiopatológicas e clínica do indivíduo acometido pela Doença Reumática Cardíaca devem ser constante em prol de interpretar sinais clínicos correlacionados com a relação binominal “organismo-microrganismo” com o fito de facilitar o processo de conduta terapêutica destinada aos pacientes, uma vez que é uma patologia negligenciada pela comunidade científica.
Perspectivas terapêuticas em metástases hepáticas a neoplasia de colón e reto
Authors: Silva Antonia Rafaelly Fernandes , Moreira Geterson Bezerra , Carvalho Arthur de Sousa Lima , Teles João Guilherme Ourique , Lopes Juan Lucas Furtado , Teixeira Pedro Henrique Machado , Virgulino Stephannie Glozan , Costa Thayna Peres , Araújo Yasmim Tapety , Viana Ana Luíza Soares
Published: November 2020

Introdução: O câncer colorretal é um dos cânceres mais importantes e recorrentes do Brasil. Associado a estes eventos estão, comumente, quadros metastáticos, preferencialmente as lesões hepáticas, sendo assim, este estudo objetiva identificar as terapêuticas de maior ou menor morbimortalidade deste evento. Metodologia: foi realizada uma busca dos descritores relacionados à temática, os quais foram identificados utilizando o DeCS (Descritores em Ciência da Saúde). Os descritores oportunos foram sendo estes: “Metastases”, “Carcinoma Colorectal’’, “Hepatectomia’’, ‘’Morbidades’’, “mortalidade”, ‘’Estudo Comparativo’’, “ressecção de metástases hepáticas”, “complicações pós-operatória estes foram ajustados em formula de buscas aplicadas no BVS e PubMed , alcançando um número de 113 artigos (88 na primeira e 25 na segunda). Após seguidos processos de inclusão e exclusão, foram pré-definidos 10 artigos originais restaram para serem revisados. Resultados: Sobre os fatores intrínsecos ao paciente, constatou-se a necessidade de conduta individualizada, em que idade e tipo histológico são fatores preponderantes. As vias cirúrgicas mostraram melhores desfechos por via laparoscópica, em metástases solitárias, além de abordagens anatômicas, evidenciando também vantagens a técnica da cirurgia robótica, porém de difícil acesso. Discussão e Considerações finais: O presente trabalho propôs uma revisão acerca do verdadeiro benefício da hepatectomia em pacientes com metástase hepática por câncer colorretal e suas possíveis complicações, a fim de estabelecermos os melhores meios para a sobrevida desses pacientes.
Correlation of Normal Labor and Vacuum Extraction with Postlabor Stress Urinary Incontinence
Authors: Gunawan Beni , Utama Bobby I.
Published: November 2020

Objective: To determine the correlation between normal delivery methods and vacuum extraction with postpartum stress urinary incontinence in West Sumatra.Methods: This study used cross-sectional study design in the Obstetrics and Gynecology Department of the RSUP Dr. M. Djamil Padang, network hospital and Puskesmas in Padang City from October 2018-February 2019. The sampling technique was consecutive sampling. Urinary stress incontinence were assessed using a questionnaire for urinary incontinence diagnosis (QUID).Results: There was a correlation between  normal delivery and vacuum extraction with stress urinary incontinence after delivery in the province of West Sumatra (p <0.05).Conclusion: There is a correlation between  normal labour and vacuum extraction with stress urinary incontinence after delivery in the province of West Sumatra.Keywords: normal labour, stress urinary incontinence, vacuum extraction

 

Abstrak

Tujuan: Mengetahui hubungan cara persalinan normal dan vakum ekstraksi dengan stress inkontinensia urin pascasalin di Provinsi Sumatera Barat.Metode: Penelitian ini menggunakan desain potong lintang di Poliklinik Bagian Obstetri dan Ginekologi RSUP Dr. M Djamil Padang, RS jejaring dan Puskesmas di Kota Padang sejak bulan Oktober 2018-Februari 2019, Teknik pengambilan sampel dengan consecutive sampling. Penilaian stress inkontinensia urin dengan menggunakan questionnaire for urinary incontinence diagnosis (QUID).Hasil :Terdapat hubungan  persalinan normal dan vakum ekstraksi dengan stress inkontinensia urin pascasalin di provinsi Sumatera Barat (p<0,05).Kesimpulan : Penelitian menyimpulkan terdapat hubungan persalinan normal dan vakumekstraksi dengan stressinkontinensia urin pascasalin di provinsi Sumatera Barat.Kata kunci: persalinan normal, stres inkontinensia urin, vakum ekstraksi
Effect of Vitamin D3 Supplementation on Levator Ani Muscle Strength in Primipara Pregnancy with Post-partum Vitamin D3 Deficiency
Authors: Sukarsa Rizkar A. , Anti Devi N. , Purwara Benny H. , Sasotya R.M Sonny
Published: November 2020

Objective: To determine the benefi ts of post-partum vitamin D supplementation on striated muscle strength.

Methods: This is a pre-post quasi-experimental study on postpartum vitamin D3 supplement provision in primiparous women with vitamin D3 defi ciency. The effect of vitamin D3 supplement was assessed through the measurement of pelvic floor muscle strength before and after 3 months of vitamin D3 supplementation. Thirty-three primiparous postpartum women with spontaneous vaginal delivery who met inclusion criteria participated in this study. Serum vitamin D3 level, basal tone, and maximum levator ani contraction were measured by perimetry prior to and after vitamin D3 supplementation. This study was conducted in the Obstetric Clinic and Clinical Serology Laboratory of Clinical Pathology Department, Dr. Hasan Sadikin General Hospital/ Faculty of Medicine, Universitas Padjadjaran from March 1 to May 31, 2018.Results: Data analysis using the Wilcoxon test showed an increase in serum vitamin D3 level and a basal tone strength after vitamin D3 supplementation with a P-value of <0.001. However, the maximum strength of levator ani muscle contraction did not increase (P-value <0.829).Conclusions: Vitamin D3 supplementation increases basal tone strength.Keywords: basal tone, maximum levator ani muscle contraction, perimetry, primiparous vitamin D3 defi ciency, vitamin D.

Abstrak

Tujuan: Untuk mengetahui manfaat pemberian suplementasi vitamin D pascasalin terhadap kekuatan otot lurik.Metode: Tipe penelitian ini adalah penelitian eksperimental quasi dengan rancangan sebelum dan sesudah pemberian vitamin D3 pada ibu primipara pascasalin yang mengalami defisiensi vitamin D3, dengan mengukur kekuatan otot dasar panggul sebelum dan sesudah pemberian 3 bulan vitamin D3. Subjek penelitian adalah primipara pasca persalinan spontan yang memenuhi kriteria inklusi penelitian (n=33). Dilakukan pemeriksaan kadar vitamin D serum dan pengukuran tonus basal dan kontraksi maksimal levator ani dengan menggunakan perimetri sebelum dan sesudah pemberian suplementasi vitamin D3. Penelitian dilakukan di Poliklinik obstetri FKUP/RSHS dan Laboratorium serologi Klinik Patologi Klinik FKUP/RSHS pada bulan 1 Maret- 31 Mei 2018.Hasil: Hasil penelitian ini dengan menggunakan uji wilcoxon didapatkan peningkatan kadar serum vitamin D3 dan peningkatan kekuatan tonus basal setelah pemberian suplementasi vitamin D3 dengan nilai P<0,001. Sedangkan kekuatan kontraksi otot maksimal levator ani tidak mengalami peningkatan dengan nilai P<0,829.Kesimpulan: Suplementasi vitamin D3 meningkatkan kekuatan tonus basalKata kunci: kontraksi maksimal levator ani, perimetri, primipara defi sisensi vitamin D3, tonus basal, vitamin D.
Quality of Life Assessment in Patient who Underwent Chemotherapy in Gynaecologic Oncology Division
Authors: Winarto Hariyono , Halim William
Published: November 2020

Abstract

Objective: To determine the quality of life in cancer patients who underwent chemotherapy treatment.Methods: A cross-sectional study was conducted from June to August 2019. Patients with cancer, who had undergone chemotherapy and willing to participate were included in this study. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-30 (EORTC QLQ–30) questionnaire was used as the measurement tool. The patients were grouped into three groups based on the cycles of chemotherapy.Results: Sixty three responders participated in the study. As the treatment progressed, there was a signifi cant decrease in Global Health Status (GHS) and social function. In symptom scales, there was a signifi cant increase in nausea and vomiting, pain, and insomnia.Conclusions: There was a decrease in the quality of life in patients with gynecological cancer who underwent chemotherapy in dr. Cipto Mangunkusumo National General Hospital. This result should be an evaluation for the healthcare provider to implement a holistic approach in managing cancer patients.Keywords: chemotherapy, gynaecological cancer, quality of life. 

Abstrak

Tujuan: Untuk menilai kualitas hidup pasien kanker yang menjalani kemoterapi.Metode: Penelitian dilakukan dengan metode potong lintang, dilakukan dari Juni hingga Agustus 2019. Semua pasien dengan kanker yang menjalani kemoterapi dan bersedia mengikuti penelitian diikutsertakan dalam penelitian ini. Penilaian dilakukan menggunakan kuisioner dari The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-30 (EORTC QLQ- 30) digunakan. Pasien dikelompokkan menjadi 3 kelompok berdasarkan siklus kemoterapinya.Hasil: Terdapat 63 pasien yang berpartisipasi dalam penelitian ini. Seiring pengobatan, terdapat penurunan signifikan pada global health status (GHS) dan fungsi sosial. Gejala yang meningkat secara signifi kan antara lain mual dan muntah, nyeri, dan insomnia.Kesimpulan: Terdapat penurunan kualitas hidup pada pasien kanker ginekologi yang menjalani kemoterapi di Rumah Sakit Dr. Cipto Mangunkusumo. Hasil penelitian ini menjadi evaluasi untuk penyedia layanan kesehatan agar dapat menangani pasien kanker secara holistik.Kata kunci: kanker ginekologi, kemoterapi, kualitas hidup.
Some remarks on the contribution of Amedeo Giovanni Conte to a philosophical sociology of law
Authors: Colloca Stefano
Published: November 2020

Although Amedeo Giovanni Conte investigated questions relevant to legal sociology through several decades of studies and discussions, his works specifically addressed to a philosophical sociology of law were mainly written between 2000 and 2011. Through these works Conte has noticeably contributed to shape some basic categories for legal sociology in different areas: the relationship between norm and action, the problem of inference of rules from observed behaviour, the principle of effectiveness, the relationship between law and language. This arti-cle discusses Conte's theory of nomotropism (acting in function of rules) also in the light of the Friedmanian theory of the impact of law. Conte's research, since it is addressed to the elaboration of basic categories which can be used by other scholars to undertake either theoret-ical or empirical investigations, could be conceived of as a contribution towards a pure (reine) sociology of law.
Mechanical Engineering in Ancient Egypt, Part 92: Tomb Inscription During the Old Kingdom
Authors: Hassaan Galal Ali
Published: November 2020

This work is based on a previously published hypothesis which proposed that the solid matter of the universe can be represented as a vibrational wave of energy propagating over an ether or matrix through a mechanism that scrambles the degree of duality in matter: x% localized (solid), y% delocalized (wave). The main purpose of this paper is to present a two-dimensional approximation of the three-dimensional structure of the shape of the energy distribution of an atomic orbital to propose a mechanism through which the orbital can be transported as a vibration from a point A to point B in the matrix. This process requires cycles or oscillations of mounting-dismounting-remounting in which what travels from point A to point B is the energy forming the orbital and not the solid matter that it can form. The atomic seven-dimensional f orbital of hydrogen-like atoms is used as a model to show an analogy to the transformations that it can be submitted to when transported over the matrix.
Лингвистические и лингводидактические основы обучения студентов-юристов иноязычному профессиональному общению в условиях коллизии правовых культур
Authors: Яроцкая Людмила , Алейникова Дарья , Бондарчук Галина
Published: November 2020

Монография представляет собой научное издание, посвященное обоснованию новой содержательной модели обучения студентов-юристов иноязычному профессиональному общению в условиях коллизии правовых культур как пограничной формы диалогового общения таких культур. Расширение перспективы научного осмысления объекта – современного пространства «межкультурного диалога» юристов – определило возможность применения комплекса лингвокогнитивных инструментов экспликации правовой сферы, соотнесения результатов лингвокультурологических, дискурсивных, межкультурных исследований, их лингводидактической интерпретации и целенаправленного использования для проектирования содержательной модели обучения целевого контингента. Издание адресовано научным работникам, специалистам по межкультурной коммуникации, преподавателям и аспирантам.
A fitnesztrendek és új típusú mozgásformák társadalmi és gazdasági aspektusai
Authors: Müller Anetta , Bácsné Bába Éva , Gabnai Zoltán , Pfau Christa , Pető Károly
Published: November 2020

A fitneszipar társadalmi-gazdasági jelentősége mára megkérdőjelezhetetlenné vált, melyet egyre növekvő méretei és piaci részesedése is jól bizonyítanak. Az egészséges életmód térnyerése mellett növekszik a kereslet a különféle szabadidős tevékenységek iránt. Az európai egészség- és fitneszpiac 2017-ben és 2018-ban is növekedett, melyet mind a fitneszklubok számának, mind a tagok számának és azok költéshajlandóságának növekedése eredményezett. Kutatásunkban az Észak-alföldi régióban működő fitnesztermek körében mélyinterjús kutatást végeztünk (N=33). Elemeztük, hogy a régióban működő fitnesztermek szolgáltatásai hogyan viszonyulnak napjaink nemzetközi fitnesz trendjeihez. Arra kerestük a választ, hogy a szolgáltatók a sportkínálatukban hogyan jelenítik meg a fogyasztói trendeket. Az eredmények azt mutatják, hogy azok a különböző edzésmódszerek, mozgásformák és funkcionális tréning gyakorlatok jelennek meg a szolgáltatók népszerű kínálatában, melyek leginkább alkalmasak arra, hogy a fogyasztók teljesítőképességét és fittségi szintjét növeljék.
A magyar sportvállalkozások kiegészítő mellékleteinek vizsgálata a mérleghez kapcsolódóan
Authors: Kerezsi Dóra , Erdey László
Published: November 2020

Napjainkban megnőtt és megváltozott a sport szerepe, mostanra az eredetileg civil, mozgáson alapuló, szabadidős magántevékenységből egy külön területté vált. A sport az egyik legmeghatározóbb eleme a világgazdaságnak, folyamatosan újabb és újabb piacokat nyit meg, mely során megjelentek a profitorientált vállalatok is. Ezen iparág GDP-ben mérhető hatása egyre nagyobb és erőteljesebb növekedést mutat. A mai globalizált és felgyorsult világban nélkülözhetetlen, hogy a vállalkozások naprakész információkkal rendelkezzenek. A gazdasági élet kihívásainak az a vállalat tud megfelelni, amely rendelkezik a szükséges információkkal. A nyilvános információk egyik forrása lehet a 2000. évi C. törvény előírásai alapján elkészített és közzétett számviteli beszámoló. A számviteli beszámoló három részből áll, a mérlegből, az eredménykimutatásból és a kiegészítő mellékletből. A kiegészítő melléklet szöveges információi a számszerű adatok pontosabb értelmezéséhez szükségesek. A vállalatok hatékony működéséhez, a megfelelő döntéshozatalhoz, a kockázatok értékeléséhez nyújthat segítséget egy-egy piaci szereplő (vevők, szállítók, versenytársak stb.) kiegészítő melléklete. Kutatásunkban azt vizsgáljuk, hogy a vállalatok által elkészített kiegészítő mellékletek tartalmazzák-e azokat az információkat, amelyek segítségével a partner vállalatokra vonatkozó szükséges pénzügyi ismeretek megszerezhetők. A vizsgálathoz a 931-es TEÁOR számú, főtevékenységként Sporttevékenységet megadó vállalatokat kiegészítő mellékleteit használtuk fel. Szövegbányászat segítségével azt vizsgáljuk, hogy a kiegészítő mellékletek mennyiben felelnek meg a számviteli törvény általi előírásoknak.
Susceptibility to Soil Erosion and Risk Assessment at Hilly Farms Using Geospatial Techniques
Authors: N.M. Nasidi , A. Wayayok , A. F. Abdullah , M. S. M. Kassim
Published: November 2020

Soil erosion is a serious environmental challenge which persistently diminishes available land resources globally.The impact of soil erosion is more severeat hilly regions where various techniques are deployed to evaluateits risk levels. However, the traditional approach of estimating the magnitude of erosion is tedious, costly, and considerably time consuming. This study was intended to assess the risk associated with soil erosion at hilly areas of Cameron Highlands through geospatial means. The Digital Elevation Model (DEM) with 5m resolution from Interferometric Synthetic Aperture Radar (IfSAR) was utilized to generate the slope inthe highlands. Soil erosion rates was estimated using Universal Soil Loss Equation (USLE), while information about land use and cover were sourced from relevant government agencies. Inversed Distance Weighted (IDW) method of spatial interpolation was applied to predict the values of unknown pixels. The analysis shows that, there is 217.5 km2of the highlands which is greater than 45-degreeaccounted for about 30.5% of the total land area. Moreover, erosion risk assessment indicated that 66.3%, 11.4%, 11.7% and 10.8% are respectively classified as very low, law, moderate and high susceptible to soil erosion. In general, the risk of soil erosion is relatively low and could be attributed to den sevegetation coverage within the study watershed despite the steep slopes where it was found to be at very high risk to soil erosion susceptibility. However, there is need to deploy best management practices to reduce the effect of soil disturbances at hilly areas and prevent excessive soil loss in future.
Choreographing the liturgy: exploring continuity, change and the liturgy in the ecclesiastical buildings of Gillespie, Kidd & Coia
Authors: Robertson James
Published: November 2020

This is a study of a process of architectural analysis on Gillespie, Kidd & Coia (1927–1987), an architectural practice often famed for their original approach, especially for their longstanding client, the Catholic Archdiocese of Glasgow. It is primarily concerned with the results of their approach over many years; of the effects or trends apparent in their work as an oeuvre, rather than with their initial architectural intentions; and builds on the work of other scholars by discussing the firm's work within the context of the twentieth century's rather fluid liturgical landscape. An alternative method is suggested for reading their ecclesiastical architecture, based not only on difference within their work, but also on its interconnections.
El tratamiento actual de la Diabetes Mellitus Tipo 2
Authors: Garmendia-Lorena Fausto
Published: November 2020

El tratamiento eficaz de la diabetes mellitus comenzó con el descubri- miento de la insulina en 1921 y su administración en el año 1922 por Banting, Best, MacLeod y Collip; posteriormente se introdujeron los hipoglicemiantes orales que, resultaron ser más eficaces en el control de la diabetes mellitus tipo 2 (DM2) y no así en la diabetes tipo 1 (DM1), debido a la necesidad de contar con alguna reserva pancreá- tica de insulina que se pierde  rápidamente en la DM1.
El Sistema Neuroendocrino. Manual de fisiología, fisiopatología y exploración
Authors: Morales-Soto Nelson Raúl
Published: November 2020

El autor, distinguido Endocrinólogo, investigador y docente universitario describe en el Prólogo: “Este libro está destinado a los estudiantes de Medicina que inician el Ciclo Clínico, a los médicos generales y a los profesionales especialistas no endocrinólogos.
Hipoglicemiantes orales en el tratamiento actual de la Diabtetes Mellitus tipo 2
Authors: Arbañil- Huamán Hugo César
Published: November 2020

Se describe la evolución del concepto del efecto incretina y su aplicación al desarrollo de medicamentos que ayudan al control de la glicemia en personas con diabetes mellitus tipo 2 (DM2). Al encontrarse que este efecto estaba alterado en personas con DM2 y descubrir la enzima que metaboliza a estas hormonas intestinales, se empezó el desarrollo de inhibidores cada vez más específicos de la enzima dipeptidil peptidasa-4 (DPP-4). Posteriormente, se presenta los resultados de los estudios de seguridad cardiovascular y sobre el posicionamiento de estos medicamentos en las guías de manejo de la DM2.
Patología molecular del cáncer
Authors: Doimi-García Franco , Gonzales-Paredes Alexia , Velarde-Alvarez Richard Dyer , Pinto-Oblitas Joseph
Published: November 2020

La patología ha ido evolucionando conjuntamente con los avances científicos y tecnológicos, siendo quizá ladisciplina oncológica donde estos avances se han incorporado más rápidamente a la práctica diaria. La patología molecular nace de los avances en la comprensión del genoma humano y la subsecuente descripción de los genomas del cáncer, así como de la rápida simplificación y abaratamiento de las técnicas moleculares. La patología molecular ofrece no solo una descripción más comprehensiva de las características del cáncer, sino que también le otorga al médico encargado del tratamiento, un abanico de debilidades del cáncer que son blancos terapéuticos.
Inhibidores del sistema renina-angiotensina-aldosterona y el riesgo de corona virus
Authors: Calderón-Velasco Rolando
Published: November 2020

Hay preocupación sobre el potencial o aumentado riesgo relacionado a medicamentos que actúan sobre el sistema renina-angiotensina-aldosterona en pacientes expuestos a la enfermedad del corona virus (COVID-19), porque el receptor viral es la enzima convertidora de la angiotensina.
Emergent systematicity in Tây Bồi (Vietnamese Pidgin French)
Authors: Mayeux Oliver
Published: November 2020

Early pidgins have been traditionally characterized as ‘fluid, structureless, and probably macaronic’ (Bickerton 1999: 54). According to this view, this unstructured code is only systematized when it is acquired by children during creolization. Presented here is a preliminary generative analysis of data from Tây Bồi/Vietnamese Pidgin French (VPF), a now-extinct pidgin which existed during the French colonization of Vietnam (Schuchardt 1888; Stageberg 1956; Reinecke 1968; Philips 1975; Nguyễn 1979; Love 2000). VPF was never acquired as an L1 nor fully elaborated; it therefore did not creolize, remaining unambiguously at the pidgin stage. Data from the 19th and 20th centuries suggest that, contrary to the predictions of the Bickertonian pidgin-to-creole model, VPF already exhibited a degree of grammatical systematicity. This poster explores the hypothesis that emergent systematicity in VPF grammar can be attributed to adult acquirers' overgeneralizations across the intake (Maximise Minimal Means; Biberauer 2019).
Unconventional Monetary Policies: Lessons from the Past and the Present to Future Monetary Policy Frameworks
Authors: Duarte Cristiano Boaventura , Modenesi André , Licha Antonio , Carré Emmanuel
Published: November 2020

This article intends to debate important aspects related to past and recent experiences of monetary policy accommodation, focusing on unconventional monetary policies. We intend to draw lessons from these experiences to discuss the design of future monetary policy frameworks.First, by reporting several historical experiences of major central banks, we highlight that policies which after 2008 crisis were considered “unconventional” were not new, with central banks intervening to avoid broader deterioration of macro-financial conditions.Moreover, analyzing the experience of the European Central Bank after 2008, we observe this institution has adapted its measures according to its former programs and to other central banks' experiences, to face numerous challenges and enhance its framework. Finally, we argue that central banks need to take advantage of past and recent experiences to improve the design of their future monetary policy frameworks under an evolutionary perspective. Based on this, measures previously implemented would have three possible destinations in new frameworks: i) Be discarded, due to their predominantly adverse effects; ii) Not be regularly implemented, but be kept as backstop mechanisms if needed; iii) Be incorporated as regular measures of monetary policy frameworks.
Bixin Protects Against Kidney Interstitial Fibrosis Through Promoting STAT6 Degradation
Authors: Li Jianzhong , Yang Youjing , Wei Shuhui , Chen Ling , Xue Lian , Tian Hailin , Tao Shasha
Published: November 2020

Bixin, a natural carotenoid extracted from the seeds of Bixa orellana, has antioxidant and anti-inflammation effects. However, the pharmacological effects and underlying mechanisms of bixin in kidney interstitial fibrosis remain unknown. Partial epithelial-to-mesenchymal transition (EMT) of tubular cells has been linked to renal interstitial fibrosis. Here, we found that in the unilateral ureteral obstruction model, bixin administration could ameliorate kidney interstitial fibrosis. The expression of signal transducer and activator of transcription 6 (STAT6) was dramatically increased in renal tubular cells. Bixin treatment inhibited STAT6 induction. The activation of STAT6 signaling was essential for transforming growth factor β1, fibrotic markers, and EMT-related protein expression in HK2 cells, which was confirmed by using the Stat6–/– mice. Ubiquitination, but not the acetylation level of STAT6, was induced by bixin treatment and promoted the suppression of phosphorylation and stability of STAT6. P62-dependent autophagy might be involved in this process. The study demonstrated that bixin can be exploited therapeutically to alleviate renal interstitial fibrosis by targeting STAT6 signaling deactivation.
Puparial Cases as Toxicological Indicators: Bioaccumulation of Cadmium and Thallium in the Forensically Important Blowfly Lucilia sericata
Authors: Malejko Julita , Deoniziak Krzysztof , Tomczuk Marlena , Długokencka Joanna , Godlewska-Żyłkiewicz Beata
Published: November 2020

In this study, we present entomotoxicological data on the accumulation of cadmium and thallium in a forensically important blowfly, Lucilia sericata, and evaluate the reliability and utility of such information as toxicological evidence for poisoning as a cause of death. We observed that Cd and Tl content in different growing stages of L. sericata (larvae, puparial cases, and adults) was increasing with increasing metal concentration in the feeding substrate, namely metal-enriched liver. However, patterns of accumulation differed between the two metals investigated, showing a linear relationship for Cd and a saturable pattern for Tl. For cadmium, the highest bioaccumulation factor (BAF) was found in the larval stage (in the range of 0.20–0.25), while for thallium, puparial cases accumulated more metal than the other stages tested (BAF in the range of 0.24–0.42). Thallium was also observed to have a negative effect on larval growth, resulting in lower weight and smaller puparial size. With this study, we update the information on the bioaccumulation of cadmium in forensically important blowflies and provide the first report on the bioaccumulation of thallium as well as its developmental impact in blowflies. Specifically, our results suggest that analysis of puparial cases could yield useful information for entomotoxicological investigations. The content of Cd and Tl in larvae, puparial cases, and adults of L. sericata was determined by inductively coupled plasma mass spectrometry (ICP-MS). The validation parameters of the method such as sensitivity, detection limits, quantification limits, precision, and accuracy were evaluated. The method detection limit (MDL) for all types of samples was in the range of 1.6–3.4 ng g−1 for Cd and 0.034–0.15 ng g−1 for Tl, and the accuracy of the method was confirmed by a high recovery of metals from certified reference materials (91.3% for Cd and 94.3% for Tl).
Asymptomatic Malaria Infection Is Maintained by a Balanced Pro- and Anti-inflammatory Response
Authors: Frimpong Augustina , Amponsah Jones , Adjokatseh Abigail Sena , Agyemang Dorothy , Bentum-Ennin Lutterodt , Ofori Ebenezer Addo , Kyei-Baafour Eric , Akyea-Mensah Kwadwo , Adu Bright , Mensah Gloria Ivy , Amoah Linda Eva , Kusi Kwadwo Asamoah
Published: November 2020

Background

Pro- and anti-inflammatory cytokines are important mediators of immunity and are associated with malaria disease outcomes. However, their role in the establishment of asymptomatic infections, which may precede the development of clinical symptoms, is not as well-understood.

Methods

We determined the association of pro and anti-inflammatory cytokines and other immune effector molecules with the development of asymptomatic malaria. We measured and compared the plasma levels of pro-inflammatory mediators including tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), interleukin (IL)-6, IL-12p70, IL-17A, and granzyme B, the anti-inflammatory cytokine IL-4 and the regulatory cytokine IL-10 from children with asymptomatic malaria infections (either microscopic or submicroscopic) and uninfected controls using Luminex.

Results

We show that individuals with microscopic asymptomatic malaria had significantly increased levels of TNF-α and IL-6 compared to uninfected controls. Children with either microscopic or submicroscopic asymptomatic malaria exhibited higher levels of IFN-γ, IL-17A, and IL-4 compared to uninfected controls. The levels of most of the pro and anti-inflammatory cytokines were comparable between children with microscopic and submicroscopic infections. The ratio of IFN-γ/IL-10, TNF-α/IL-10, IL-6/IL-10 as well as IFN-γ/IL-4 and IL-6/IL-4 did not differ significantly between the groups. Additionally, using a principal component analysis, the cytokines measured could not distinguish amongst the three study populations. This may imply that neither microscopic nor submicroscopic asymptomatic infections were polarized toward a pro-inflammatory or anti-inflammatory response.

Conclusion

The data show that asymptomatic malaria infections result in increased plasma levels of both pro and anti-inflammatory cytokines relative to uninfected persons. The balance between pro- and anti-inflammatory cytokines are, however, largely maintained and this may in part, explain the lack of clinical symptoms. This is consistent with the generally accepted observation that clinical symptoms develop as a result of immunopathology involving dysregulation of inflammatory mediator balance in favor of pro-inflammatory mediators.
Participation of Endosomes in Toll-Like Receptor 3 Transportation Pathway in Murine Astrocytes
Authors: Mielcarska Matylda B. , Gregorczyk-Zboroch Karolina P. , Szulc-Dąbrowska Lidia , Bossowska-Nowicka Magdalena , Wyżewski Zbigniew , Cymerys Joanna , Chodkowski Marcin , Kiełbik Paula , Godlewski Michał M. , Gieryńska Małgorzata , Toka Felix N.
Published: November 2020

TLR3 provides immediate type I IFN response following entry of stimulatory PAMPs into the CNS, as it is in HSV infection. The receptor plays a vital role in astrocytes, contributing to rapid infection sensing and suppression of viral replication, precluding the spread of virus beyond neurons. The route of TLR3 mobilization culminating in the receptor activation remains unexplained. In this research, we investigated the involvement of various types of endosomes in the regulation of the TLR3 mobility in C8-D1A murine astrocyte cell line. TLR3 was transported rapidly to early EEA1-positive endosomes as well as LAMP1-lysosomes following stimulation with the poly(I:C). Later, TLR3 largely associated with late Rab7-positive endosomes. Twenty-four hours after stimulation, TLR3 co-localized with LAMP1 abundantly in lysosomes of astrocytes. TLR3 interacted with poly(I:C) intracellularly from 1 min to 8 h following cell stimulation. We detected TLR3 on the surface of astrocytes indicating constitutive expression, which increased after poly(I:C) stimulation. Our findings contribute to the understanding of cellular modulation of TLR3 trafficking. Detailed analysis of the TLR3 transportation pathway is an important component in disclosing the fate of the receptor in HSV-infected CNS and may help in the search for rationale therapeutics to control the replication of neuropathic viruses.
A New Spiking Convolutional Recurrent Neural Network (SCRNN) With Applications to Event-Based Hand Gesture Recognition
Authors: Xing Yannan , Di Caterina Gaetano , Soraghan John
Published: November 2020

The combination of neuromorphic visual sensors and spiking neural network offers a high efficient bio-inspired solution to real-world applications. However, processing event- based sequences remains challenging because of the nature of their asynchronism and sparsity behavior. In this paper, a novel spiking convolutional recurrent neural network (SCRNN) architecture that takes advantage of both convolution operation and recurrent connectivity to maintain the spatial and temporal relations from event-based sequence data are presented. The use of recurrent architecture enables the network to have a sampling window with an arbitrary length, allowing the network to exploit temporal correlations between event collections. Rather than standard ANN to SNN conversion techniques, the network utilizes a supervised Spike Layer Error Reassignment (SLAYER) training mechanism that allows the network to adapt to neuromorphic (event-based) data directly. The network structure is validated on the DVS gesture dataset and achieves a 10 class gesture recognition accuracy of 96.59% and an 11 class gesture recognition accuracy of 90.28%.
Sexual Health in Child and Adolescent Psychiatry: Multi-Site Implementation Through Synchronized Videoconferencing of an Educational Resource Using Standardized Patients
Authors: Drozdowicz Linda , Gordon Elisabeth , Shapiro Desiree , Jacobson Sansea , Zalpuri Isheeta , Stewart Colin , Lewis A. Lee , Robinson Lee , Myint Myo Thwin , Daniolos Peter , Williamson Edwin D. , Pleak Richard , Graeff Martins Ana Soledade , Gleason Mary Margaret , Galanter Cathryn A. , Miller Sarah , Stubbe Dorothy , Martin Andrés
Published: November 2020

Objective: Matters of sexuality and sexual health are common in the practice of child and adolescent psychiatry (CAP), yet clinicians can feel ill-equipped to address them with confidence. To address this gap in training and practice, we developed, implemented, and evaluated an educational module enhanced by videotaped depictions of expert clinicians interacting with professional actors performing as standardized patients (SPs).

Methods: We developed an educational resource highlighting common issues of sexual health relevant to CAP practice, including sexual development, psychotropic-related side effects, and sexuality in children with autism. We wrote original scripts, based on which two clinicians interacted with three SPs. Digital recordings were edited to yield 5 clips with a cumulative running time of 20 min. The clips were interspersed during a 90-min session comprising didactic and interactive components. Due to the COVID-19 pandemic, we used synchronous videoconferencing, which allowed content dissemination to several training programs across the country.

Results: We recruited 125 learners from 16 CAP training programs through the American Academy of CAP's Alliance for Learning and Innovation (AALI). Routine inquiry into adolescent patients' sexual function was uncommon, reported by only 28% of participants, with “awkward” and “uncomfortable” the most common terms mentioned in reference to the clinical task. The didactic intervention led to measurable improvements after 2 weeks in skills and knowledge (p = 0.004) and in attitudes (p < 0.001). The three items with the greatest improvement were: (a) availability of developmentally tailored resources; (b) comfort in addressing sexual development with underage patients; and (c) with parents or guardians of neuroatypical or developmentally disabled patients (p < 0.001 for each).

Conclusions: A sexual health curriculum enriched by video-based examples can lead to measurable improvement in outcomes pertinent to the clinical practice of CAP. These educational materials are available for distribution, use and adaptation by local instructors. Our study also provides proof-of-principle for the use of multisite educational initiatives in CAP through synchronized videoconferencing.
Static Aeroelasticity Using High Fidelity Aerodynamics in a Staggered Coupled and ROM Scheme
Authors: Kafkas Angelos , Lampeas George
Published: November 2020

Current technology in evaluating the aeroelastic behavior of aerospace structures is based on the staggered coupling between structural and low fidelity linearized aerodynamic solvers, which has inherent limitations, although tried and trusted outside the transonic region. These limitations arise from the assumptions in the formulation of linearized aerodynamics and the lower fidelity in the description of the flowfield surrounding the structure. The validity of low fidelity aerodynamics also degrades fast with the deviation from a typical aerodynamic shape due to the inclusion of various control devices, gaps, or discontinuities. As innovative wings tend to become more flexible and also include a variety of morphing devices, it is expected that using low fidelity linearized aerodynamics in aeroelastic analysis will tend to induce higher levels of uncertainty in the results. An obvious solution to these issues is to use high fidelity aerodynamics. However, using high fidelity aerodynamics incurs a very high computational cost. Various formulations of reduced order models have shown promising results in reducing the computational cost. In the present work, the static aeroelastic behavior of three characteristic aeroelastic problems is obtained using both a full three-dimensional staggered coupled scheme and a time domain Volterra series based reduced order model (ROM). The reduced order model’s ability to remain valid for a wide range of dynamic pressures around a specific Mach number (and Reynolds number regime if viscous flow is considered) and the capability to modify structural parameters such as damping ratios and natural frequencies are highlighted.
The Comparison of Constant and Dynamic Red and Blue Light Irradiation Effects on Red and Green Leaf Lettuce
Authors: Viršilė Akvilė , Miliauskienė Jurga , Haimi Perttu Juhani , Laužikė Kristina , Samuolienė Giedrė
Published: November 2020

In this study, we sought to evaluate and compare the effects of constant and dynamic lighting on red and green leaf lettuce (Lactuca sativa L. Red Cos and Lobjoits Green cos) cultivated in a controlled environment. Plants were illuminated with the combination of red 662 and 638 nm, blue 452 nm, and far-red 737 nm at 16 h photoperiod and constant daily light integral (DLI) of each component. Five constant or dynamic lighting treatments were performed: (BR) constant flux of both B452 and R662; (B*R) constant flux of R662, but the DLI of B452 condensed in 8 h in the middle of photoperiod doubling the PPFD of blue light; (BR*) constant flux of B452, but the DLI of R662 light condensed in the middle of photoperiod; (BdynR) constant flux of R662, but the flux of B452 varies in the sinusoidal profile during 16 h photoperiod, imitating diurnal increase and decrease in lighting intensity; and (BRdyn) constant flux of B452, but the flux of R662 varies in sinusoidal profile. The lettuce’s response to dynamic lighting strategies was cultivar specific. Dynamic lighting strategies, mimicking natural lighting fluctuations, did not have a remarkable effect on photosynthesis and antioxidative parameters, but the dynamic flux of blue light component had a pronounced effect on higher macro and microelement contents in lettuce leaves.