bluuebunny/crossref_metadata_2025 huggingface dataset:
Melting in the Daylight: The Asrai’s emergence in modern myth
Authors: Allison Sarah
Published: October 2023

The Asrai is a nocturnal fairy popularly attributed to British folklore, most memorable for the fact that any exposure to sunlight will cause it to melt into water. Rather than developing from oral folk tradition, like most legendary creatures, the Asrai may have originated and evolved through literary sources, beginning with the poetry of the Scottish author Robert Buchanan in the 1870s. Since appearing in a folklore account of uncertain provenance in 1970, the Asrai has come into use as a fantasy creature with international spread, developing in a dialogue between print media and the Internet.
Lagoon Wanderings: Boat hydro-perspectivism in the aquapelagic assemblage of the Venetian Lagoon
Authors: Codato Petra
Published: October 2023

In this article I conduct the reader along a journey that follows different waterways within the Venetian lagoon and provides insights into the water-land interactions of this unique aquapelagic assemblage. Leveraging the methodological tool of hydro-perspectivism, I situate the analytical standpoint within two very different kinds of boat: the vaporetto (a local waterbus) and the kayak. The first, native to the lagoon, gives voice to a sample of the massive population of tourists that constantly crowds the lagoon’s islands and waters. Navigating the congested waterways leading from the Lido littoral to Venice’s historical centre, I raise issues such as over-tourism, water quality, and wave motion. Shifting the perspective to the kayak, a type of boat that originates in Inuit culture and is perfectly suited to the lagoon's shallow waters, the article then investigates the potentialities of analysing from the water’s edge, considering other serious problems of the Venetian aquapelago, such as pollution and hydro-morphological alterations. In conclusion, I argue that by conceiving the boat as not only as a means of transport but also as a means of acquiring and formulating knowledge, it is possible to revitalise hydrophilic feelings and thus the precious aquapelagic identity of Venice’s lagoon that has been in decline over the last century.
Fluid Ecologies, Sovereignty, and Colonialism: Princely contestations over riverine islands in colonial India
Authors: Sudhindranath Mahendranath , Lourdusamy John
Published: October 2023

This article analyses the disputes over riverine islands between two princely states in colonial southern India in the 19th and early 20th centuries. These disputes arose because of changes in the islands’ landmass caused by water movements. Such tidal temporalities challenged cartographic rigidities and the established notions of sovereignty of states. What were assumed to be sovereign, undisputed and infallible were unsettled by such hydrological power and the fluid ecologies involved. A set of challenges emanated from external concepts arising from colonialism which undermined the native geographical understanding of the land-water continuum due to the monetisation of land. This article makes a critical appraisal of this double challenge to the traditional understanding of fluid ecologies while also highlighting the counter challenges from the princely states. These contests were particularly pronounced as the princely states had considerable autonomy in internal matters of administration and thus differed from the rest of the colonial territory directly ruled by the British in India. The article contributes to the study of riverine islands by investigating the nature and fluidity of shifting islands, whose variation in temporal contexts has been barely acknowledged in Island Studies to date.
Intravenous Thrombolysis is Effective in Mild Stroke Patients with an Admission NIHSS Score of 3 to 5
Authors: Zhang Kai , Han Lin
Published: November 2023

Background and Purpose:

The role of intravenous thrombolysis in patients with
acute mild ischemic stroke remains highly controversial. Therefore, this study aims to analyze
the efficacy and safety of intravenous thrombolysis in patients with mild ischemic stroke based
on admission National Institutes of Health Stroke Scale (NIHSS) score.

Methods:

The present study enrolled 507 patients with acute mild ischemic stroke admitted
within 4.5 hours of symptom onset with an admission NIHSS score of 0 to 5. Patients were assigned
to two groups based on admission NIHSS scores of 0 to 2 and 3 to 5, and subsequent
analyses compared functional outcomes between thrombotic and non-thrombotic patients within
these groups. The primary outcome was a modified Rankin score (mRS) of 0 or 1 at 90 days,
representing functional independence. The safety outcomes were symptomatic intracranial hemorrhage
(sICH), early neurological deterioration (END), and the rate of stroke recurrence within
90 days.

Results:

Among the 267 patients with NIHSS scores of 0 to 2, 112 (41.9%) patients received
intravenous thrombolysis. Overall, thrombolysis administration did not significantly improve the
patient's functional prognoses at 90 days (adjusted OR=1.046, 95%CI=0.587-1.863, p = 0.878).
However, there was a marked increase in the risk of sICH (p = 0.030). Of the 240 patients with
NIHSS scores of 3 to 5, 155 (64.6%) patients received intravenous thrombolysis, resulting in a
significant improvement in 90-day functional prognosis (adjusted OR=3.284, 95%CI=1.876-
5.749, p<0.001) compared to those that did not receive thrombolysis intervention. Importantly,
there was no significant increase in sICH incidence (adjusted OR=2.770, 95%CI=0.313-24.51, p
= 0.360). There were no statistically significant differences in END or the rate of stroke recurrence
within 90 days between thrombotic and non-thrombotic groups.

Conclusions:

Intravenous thrombolysis is safe and effective in patients with baseline NIHSS
scores of 3 to 5. In contrast, it did not improve 90-day functional outcomes in patients with
NIHSS scores of 0 to 2 and instead increased the risk of sICH.
Developing Multi-epitope Antigen Construct from Immunodominant
Proteins for Serological Diagnosis of Chlamydia trachomatis: An In Silico
Approach
Authors: Ghalamfarsa Farideh , Savardashtaki Amir , Irajie Cambyz , Emami Amir , Nezafat Navid , Ghasemi Younes
Published: November 2023

Background:

Chlamydiasis is a widespread bacterial infection in the world. Serological
tests are expensive, and in addition, intrinsic antigens can cause cross-reactions and make the diagnosis
process difficult. Multi-epitope protein antigens are novel and potential diagnostic markers
that have the capability of more accurate and cheaper diagnosis. Therefore, in this study, the main
goal is to design a new protein vaccine, including multiple epitopes of B cells with dominant immunity
from three proteins named MOMP, ompA and Pgp3D from C. trachomatis

Methods:

The amino acid sequences were obtained from the UniProt database. The areas with the
highest antigenicity were identified using the EMBOSS server. Linear B cell epitopes were determined
using BCPRED, ABCpred, and Bepipred servers. Epitopes with the highest antigenicity were
connected using the EAAAK linker.

Results:

Two epitopes from MOMP, two from ompA, and one from Pgp3D were selected. These
epitopes were connected to each other with the EAAAK linker. Three residues (0.592), 16 residues
(0.76), 36 residues (0.578), and 37 residues (0.734) were obtained from the prediction of the spatial
structure of the B cell multiple epitopes designed with ElliPro. Model 1 of RaptorX was selected as the
best structure. In this model, the ERRAT quality, ProSA-web z-score, and Verify3D were 83.1169, -
5.17 and 84.62% with PASS score, respectively. Moreover, the Ramachandran plot showed that
86.093% of the amino acid residues were located in the favored region. To achieve the highest level of
protein expression, the designed multi-epitope reverse-translated with the Genscript server and was
cloned in E. coli. The highest level of expression was achieved, and a CAI score of 0.91 was reported.
The gene GC content was 51.98%, and the contribution of low-frequency codons was 0%.

Conclusion:

The results confirmed that the designed construct could identify C. trachomatis with
high sensitivity and specificity in serum samples of patients with chlamydiasis. However, further
experimental studies are needed for final confirmation.
A comprehensive review on Basic Principles of Samkhya Darshana and their implications in Charaka Samhita
Authors: Sumana Ray Paul
Published: October 2023

Samkhya Darshana is considered as one of the oldest and prominent school of Indian theistic philosophy. Traditionally propounded by Maharshi Kapila and was written as Samkhya Sutra, it became lost with the passage of time. Around 8th century Ishwarakrishna compiled all the principles of Samkhya philosophy in Samkhyakarika which is now considered as the most important textual resource. Samkhya philosophy propounds various metaphysical theories notably theory of Karya Karana Siddhanta as Sat Karya Vada, theory of Prakriti and Purusha, theory of evolution of universe, theory of three Gunas of Prakriti along with its unique triad of epistemology. Charaka Samhita being the most important compendium of Ayurveda has got inspired by many such philosophical theories of different philosophical schools, Samkhya and Vaisheshika being the most important among them. Charaka Samhita has adopted many philosophical understandings of Samkhya and subsequently implied them to form its own unique philosophical principles. The implications of such many theories of Samkhya like Sat Karya Vada, Prakriti and Purusha, Tri-Guna, theory of evolution of this universe and application of Pramana Vigyana (theory of knowledge) can be found in throughout Charaka Samhita. It is interesting to see how instead of blindly adopting those theories of Samkhya, Charaka Samhita has modulated them incorporating the understandings of its authors to frame out its own philosophical principles and to apply them in fulfilment of the chief objectives of Ayurveda like maintenance of health of a healthy person and alleviation of disease from a diseased person. In this study the author has tried to analyse the principle philosophical understandings of Samkhya Darshana and how those are later adopted in Charaka Samhita.
Vegan diet consumption according to Prakrti mentioned in Ayurved (Vata, Pitta, Kapha)
Authors: Ruchita Dhabhai  , Brahmanand Sharma  , Hemant Rajpurohit  , Rahul Parashar
Published: October 2023

Vegan diets have been increasing in popularity. A vegan diet has been linked to numerous health benefits. It has more vitamin E, iron, protein, potassium and magnesium. Vegans less thick, have lower serum cholesterol and have lower blood pressure, which lowers their risk of heart disease.[1] Aam is the result of inadequate digestion, according to Ayurveda. Considering that purpose of cleaning is to eliminate the Aama out of your gastrointestinal tract, it’s best to eat plant based meals that are high in fiber and easily digested.[2] Vata (space and air) governs movement, Pitta (fire and water) regulates metabolism, and Kapha (earth and water) manages assimilation in the body. Avoiding dairy products like milk and ghee as well as meals made from animals may also be linked to greater incidence of anxiety and sadness. Calcium, which is crucial for bones, is found in milk. The vitamin K2 in ghee will assist in milks absorption of calcium if it is added. For this reason, milk- ghee combination is recommended in ayurveda as a treatment for joint stiffness and discomfort.[3]
Anatomical exploration of Halasana
Authors: Rashmi Anil Lakhani  , GB Sharma
Published: October 2023

The word “Yoga” comes from a Sanskrit root “Yuj” which means union, or yoke, to join, and to direct and concentrate one's attention.[1,2] It is a form of mind-body fitness that involves a combination of muscular activity and an internally directed mindful focus on awareness of the self, the breath, and energy.[3] Among the eight limbs of Yoga, the Yogic technique properly begins at the third limb that is the Asana.[4] Patanjali defines Asana as ‘Sthirasukhatvam” in Yoga Sutra which can be translated as stable and agreeable. The benefits of Asana range from physical to spiritual level. Asana not only tones the muscles, ligaments, joints and nerves but also maintains the smooth functioning and health of the entire body. Anatomy[5] is basically a branch of science that deals with the study of the structures of organisms and hence, anatomy Yoga is all about understanding the inner structure of the body and its different parts and learning how Yoga poses and other practices bring changes in the body. It also revolves around the layers of the mind and energies flowing within a body. In short, Yogic anatomy teaches you in detail everything related to body organs, muscles, tissues, etc. It is important for everyone to have an in-depth knowledge of body structure so that it becomes easy for them to learn body movements, maintain alignments, and identify other functions. Halasana word comes from the word Hala means plow and Asana means posture in Sanskrit. It helps to keep the spine healthy.
End result of physical exercise with pathological increase in Lactic Acid
Authors: Dharam Chand  , Avadhesh Kumar  , Deena Nath Singh  , Shweta Mishra
Published: October 2023

Ayurveda advises adhering to the practices described by our Acharyas for well being. Ritucharya offers guidance on food plans that are suitable for overcoming the effects of seasonal fluctuations. We must adhere to the Ayurvedic prescriptions in order to maintain our mental, physical, and nutritional wellness. Between around mid-May and mid-July is the Grishma (summer) season. It is common for the ecosystem to experience intense heat and dangerous wind, and then comes the rain with heat and humidity thus the strength of individual gets decreased. According to Acharya Charak, the Vayayam is stated in Sutra Shana 7/31, which mentions that keeping the body in accordance with will power through engaging in Yogasana. For the appropriate maintenance of physical health many Acharya have explained that in Grishma Ritu exercise should be performed at half the level of actual strength and up to when sweet appear on forehead. The body's lactic acid levels rise during activity, which causes an oxygen level reduction. Exercise-induced lactic acidosis is often a temporary condition. The body's pH level drops to 7.4 to 6.6. Lactic acid levels are decreased by vitamin C, magnesium, and drinking water. Exercise also causes lactic acid levels to drop after an hour. There are many ill effect of excess lactic acid on different organs as liver, kidney, lungs, heart, muscle etc. Any source of sea food, as well as beans, leafy greens, nuts and seeds, salmon, fish and mackerel, keeps the amount of lactic acid stable.
A review of Balya action of Vidarikanda in tribal zone as mentioned in Ayurveda
Authors: Lucky Shivhare
Published: October 2023

Background: Acharya Sushruta has explained 37 Gana and each Gana has multiple indications. The nomenclature of Gana is given by the first drug in that particular Gana in Vidarigandhadi Gana. Vidarigandha is the first drug mentioned in this Gana. Each Gana is followed by its potential action on Dosha, Dhatu, Mala and clinical indication. Bala refers to the physical strength generally and any medicine that increases it is known as Balya. Folk medicine comprises of traditional healing believes and medicines used in past and contemporary cultures mostly by people who are not license medical practitioner. Folk medicine is a system based on traditional modes. Aim and Objectives: This paper trying to elaborate, evaluate and discuss the medicinal property, Balya effect of Vidarikanda. Material and Methods: The text book of Ayurveda, its commentaries and text book of modern medicine along with various clinical studies published in index journal have been review thoroughly. Discussion: Vidarikanda is very important drug, which is described from ancient time. Acharyas already know the importance of Vidarikanda in the therapeutic (Balya) management. It is indicated in Shosha, Gulma, Angamarda, Kasa, Shwasa and having Vata-Pittanashak property. Conclusion: Vidarikanda has Madhur Rasa, Shita Veerya and Guru, Snigdh Guna and it pacify Vata, Pitta and Rakta dosha and having Brihmani, Vrashya, Jivaniya, Rasayan, Stanya, Shukral, Balya property mentioned in Ayurvedic text.
A Sectoral Analysis of the Government of Karnataka's Ayurveda Budget from FY2011-12 to FY2023-24
Authors: Shakeel H Jamakhane
Published: October 2023

On the 17th of February, the Chief Minister of Karnataka presented the ₹3 Trillion Karnataka Budget. This year, the Government of Karnataka aims to spend more than ₹13,000 crores on health and family welfare. Good. The allocation for Ayurveda? ₹195 crores. Narratives shape public opinion. And the public opinion about the ascent of Ayurveda seems no different. For some, Ayurveda has grown by leaps and bounds in the past decade. For others, less so. The former narrative traces the causes of growth to, amongst other reasons, 'government support.' Is that true? This paper tries to answer the question by tracking the evolution of government support for Ayurveda in Karnataka. It does so by analysing the budget allocation for the Department of AYUSH, specifically for Ayurveda, over the past decade. The sectoral analysis presented in this paper is based on the data extracted from budget documents of the Government of Karnataka from FY2011-12 to FY2023-24. The study is limited to understanding the budgetary allocation for Ayurveda at the state level. It doesn’t take into account (for example) the grants received under Centrally Sponsored Schemes. The author concludes that when it comes to Ayurveda, the clamour surrounding Ayurveda hides more than it reveals.
The effect of Marma therapy in Student’s Elbow i.e., Olecranon Bursitis with special reference to Pain - A Single Case Study
Authors: Singh Vivek , Supriya Kurane Singh
Published: October 2023

Student's elbow, medically known as olecranon bursitis, is a common condition among students and individuals who frequently rest their elbows on hard surfaces while studying or working. This condition often leads to pain, swelling, and restricted joint movement, affecting daily activities and overall well-being. Traditional treatment approaches typically involve rest, anti-inflammatory medications, and physical therapy. However, complementary, and alternative therapies are gaining recognition for their potential in enhancing pain management and accelerating recovery. This study investigates the application of Marma therapy, an ancient Indian healing practice rooted in Ayurveda, in the management of student's elbow. Marma therapy involves stimulating vital energy points (Marma points) on the body to restore balance and promote healing. Marma therapy's holistic approach aligns well with the principles of integrative medicine, addressing not only the physical aspect of the condition but also the mental and emotional well-being of the individual. This study emphasizes the need for further research, including randomized controlled trials, to establish the effectiveness of Marma therapy in student's elbow. Additionally, practical guidelines for incorporating Marma therapy into conventional treatment plans are discussed. The integration of Marma therapy into clinical practice holds promise for providing students and individuals suffering from student's elbow with a holistic and personalized approach to pain management and rehabilitation. Hence in this study a clinically diagnosed OPD patient of Student’s Elbow is treated with Marma Chikista for 15 days provided considerable relief of pain.
Ayurvedic management of Stangranthi w.s.r. to Fibroadenoma of Breast: A Case Study
Authors: Reenu A. Sahani  , Harshad K. Jain
Published: October 2023

According to Ayurveda, Breast CA can be correlated to Granthi explained by many Acharya’s which is developing due to abnormal vitiation of Dosha and Dushya. According to Acharya Charaka, Granthi can be equated with all types of small-sized glandular or nodular swelling in any part of the body due to benign tumours or cysts. There is no direct reference for Stana Granthi but Maansaja Granthi occurs in Stana is having a close resemblance with fibroadenoma of the breast. So, in the present study, a patient with fibroadenoma was successfully treated by Ayurvedic management from Cap Boheco Peace, Raspachak Yoga, Kanchanar Guggul and Abhyanga with Chandanabala Lakshadi Taila which got the significant result.
Role of Sahacharadi Taila Matra Basti in management of Udavartini Yonivyapad w.s.r. to Primary Dysmenorrhea: A Case Study
Authors: Sudhi Kaushal  , Jitesh Kumar Panda  , Suniti Tanwar
Published: October 2023

Introduction: Dysmenorrhoea is defined as painful cramps that occur with menstruation incapacitating enough to interfere with routine activity. Dysmenorrhea is an important health problem of adolescents in school, as well as health practitioners, that badly affects the daily activities and quality of life. Dysmenorrhoea can be correlated with Udavartini Yonivyapad in Ayurveda. Methodology: In this present case study, a 21 years old female patient consulted to the OPD with the complaint of pain in lower abdomen, back pain, nausea and vomiting during menses. Her ultrasonography (USG) was done which was normal. She was supposed to be treated with Sahacharadi Taila Matra Basti; the case was treated for three months with the goal of relieving symptoms. Result: Basti was given for 5 days every month for 3 consecutive cycles. Symptoms of patient were relieved and she had pain free menstruation after three cycles of treatment. Follow-up was done after every cycle. Discussion: The present study emphasizes the role of Ayurveda in bringing a positive result in the management of Primary Dysmenorrhea.
Analysis of Made Lamongan Residential Drainage System Using SWMM (Storm Water Management Model) and HEC-RAS (Hydraulic Engineering Centre-River Analysis System) Models
Authors: Febrianto Ridwan , Bisri Mohammad , Nur Cahya Evi
Published: October 2023

Made Lamongan Residential is located in an area that has a flat slope and is flanked by two rivers Kali Mengkuli and Kali Gorok, the problem in the study area is that the drainage system is unable to serve rainwater runoff. This is evidenced by the occurrence of inundation during the rainy season with high intensity. The height of the inundation that occurs in the Residential complex ± 60 cm with a reduction in inundation of more than 12 hours. The calculation results showed that there were several sections of the channel that occurred runoff with a planned Q5 flood discharge of 8.14 m3/sec. Based on the results of surveys in the field, many channels were found that had changed their dimensions due to the renovation of residents' houses. In this study, 1D channel hydraulic modelling was carried out using SWMM and HEC-RAS software to obtain a model that was close to the surface runoff conditions at the study site. The purpose of this study is to obtain the greatest handling of inundation in Made Residential in reducing the height of the inundation based on the model to be carried out, as well as obtaining the value of model calibration at the study site.
Speed, Density, and Crash Relationship in Urban Arterial Roads
Authors: Kriswardhana Willy , Sulistyono Sonya , Yunarni Widiarti Wiwik , Ayu Rahmawaty Tiara
Published: October 2023

Vehicle speed has an essential role in the occurrence of traffic accidents. Increasing the number of vehicles operating on the road will further increase the risk of traffic accidents because it is not balanced with discipline in driving. This study's purpose is to analyze the relationship between speed and traffic accidents that occurred in Gadjah Mada and Hayam Wuruk Road, Jember, through several variations of calculations. The independent variables used are average speed and 85th percentile speed and density, while the dependent variable used is the accident rate. The analysis used is a correlation test that determines the level of closeness of the relationship between the two variables and a regression test that helps estimate the relationship between the two variables through a regression equation model that will be selected based on conditions in the field. The results of this study indicate that lower speed is associated with a lower accident rate. Meanwhile, lower vehicle density leads to an increase in the accident rate. Speed management to improve traffic safety in Indonesia is needed. Direction for future research is presented.
Possibilities of Predicting a Person's Substance Use Behaviour and Mental Health Through Social Media in a COVID-19 Crisis Context
Authors: Konstantinov Vsevolod , Ustin Pavel , Popov Leonid
Published: November 2023

The negative psychological consequences of the COVID-19 pandemic and the forced isolation of a large proportion of people worldwide have demonstrated the need to develop ways and technologies to reduce the effects of sudden threats of this type. The basis of any practical work to minimize the negative psychological consequences of the COVID-19 pandemic associated with substance use is the monitoring and diagnosis of the psychological resources of the individual. The article aims to show the possibilities of predicting the behavior of an individual through the content analysis of posts and reposts of their profile on the social network VKontakte on the example of the propensity to use psychoactive substances and to substantiate the possibilities of optimizing and automating such prediction through the use of category markers. Content analysis was carried out by latent semantic analysis of texts extracted from posts and reposts of VKontakte social network users with subsequent content analysis through selecting markers - category words. As a result, a categorical grid was built, which increases the efficiency of content analysis of posts and reposts of users and is suitable for further automation of such research by machine learning methods.
Scientific Yoga Module in the Management of Hypothyroidism: A Prospective Tele-Yoga Randomized Controlled Trial (Preprint)
Authors: Nilkantham Savithri , Singh Amit , Majumdar Vijaya , Atmakur Snigdha
Published: November 2023

BACKGROUND

The compromised quality of life is a well-documented consequence of hypothyroidism. This study evaluates the effectiveness of the Scientific Yoga Module (SYM) – a set-out protocol as an adjunct yoga intervention in improving the physiological and psychological well-being of people treated for hypothyroidism.

OBJECTIVE

The objective of this study was to determine the impact of six months of adjunct SYM on the improvement of the quality of life of patients with clinical hypothyroidism along with a secondary aim of comparing the physiological and psychological changes between the yoga intervention group and waitlist control group by assessing thyroid profile, blood pressure, body mass index, perceived stress levels, fatigue levels, and personality scales.

METHODS

This study was a single-blinded, two-arm, parallel-group randomized controlled trial (RCT) conducted for a period of six months on 134 patients (mean age, 45 SD (9.15) years) with clinical hypothyroidism randomized to either an adjunct yoga intervention or usual care. The participants received yoga intervention through tele-mode in their home settings. We recruited the participants through registries of Swami Vivekananda Yoga Anusandhana Samsthana (SVYASA) from the period 2013 to 2021. All the participants were assessed at three time points i.e., pre-interim-post for the trial conducted from 1st April 2022 to 30th September 2022. Multivariate Repeated Measures Analysis of Variance was performed for data analysis. Data was collected for the primary measure of SF36-health related quality of life scale {HRQOL} along with secondary measures of biochemical test of thyroid profile [thyroxine {T4}, triiodothyronine {T3} and thyroid-stimulating hormone {TSH}], blood pressure {BP}, body mass index {BMI}, perceived stress scale {PSS}, fatigue assessment scale {FAS} and Gita inventory of personality scale {GIP}.

RESULTS

The result reveals significant improvement in the yoga intervention group on the primary and secondary variables post-intervention compared to the waitlist control group with statistical significance at P <.001. The findings were further correlated with socio-demographic characteristics and comorbidities using Statistical Package for Social Sciences (SPSS) version 24.0.

CONCLUSIONS

SYM imparted through tele-mode for a duration of six months appears to work on varied symptoms at physical, psychological, and emotional states leading to improved overall well-being and quality of life of hypothyroid patients. None of the subjects reported any adverse events during the study period.

CLINICALTRIAL

CTRI/2022/03/041047

INTERNATIONAL REGISTERED REPORT

RR2-DOI: 10.1016/j.conctc.2023.101157
Students' critical thinking skills on human respiratory system material in flipped classroom
Authors: Simatupang Elsa Cenora , Silitonga Melva , Rajagukguk Sri Handayani
Published: October 2023

The learning process must actively involve students and provide opportunities for them to improve their critical thinking skills. This study determines the effect of the implementation flipped classroom on the critical thinking skills of students in the learning of the human respiratory system in class XI SMAN 16 Medan. This study included a quasi-experiment type with one group pretest-posttest design and was conducted in three meetings. The research instrument used is an essay test of 5 questions. Data obtained from this study include the value of students' critical thinking skills both in general and in each indicator, and the N-gain of students' critical thinking ability. The data obtained were analyzed to obtain an average value. The results of the data analysis showed that the average score of students' critical thinking skills in general increased from 39.6 before learning was carried out to 80.8 after learning was carried out. The average student score gets an N-gain score of 0.68 with the moderate improvement category. The average score of students after learning on each indicator is as follows: the basic classification indicator is in the high category (74), basic support is in the very high category (92), inference is in the high category (75), advance classification is in the high category (75), and strategy and tactics is in the very high category (88). Based on the results of the study, the flipped classroom learning model can improve the critical thinking skills of grade XI students in SMAN 16 Medan in learning the biology of the human respiratory system material.
Enhancing student conceptual understanding and critical thinking through SETS-based digital modules on environmental changes
Authors: Kustantia Evin , Miarsyah Mieke , Sigit Diana Vivanti
Published: October 2023

The rapid advancements in science and technology have necessitated the adaptation of biology education to enhance students' understanding and critical thinking skills, aligning with the demands of the 21st century. The development of digital modules based on the Science, Environment, Technology, and Society (SETS) framework represents an innovative approach to facilitate students' learning by seamlessly integrating theories from science, environment, technology, and society. This research adopts the Research and Development methodology, employing the ADDIE development model. The digital module's development underwent validation by four experts, comprising two media experts and two material experts. The validation results yielded a 90% agreement from media experts and an 85% concurrence from material experts, indicating the suitability of the digital module on environmental change, grounded in the SETS framework, for educational use. The developed module was subjected to testing using a one-group pretest-posttest design, followed by the analysis of the obtained data through paired sample t-tests. The analysis results indicate a significant improvement in both conceptual understanding and critical thinking skills following the utilization of the module. Hence, this module is recommended for use in biology education, particularly in the context of environmental change materials.
Графын чухал оройг илрүүлэх хувьслын алгоритм
Authors: Gombojav Gantulga , Purevdorj Battsengel , Purevsuren Dalaijargal
Published: October 2023

Энэхүү судалгааны ажлаар сүлжээ (граф)-ний чухал оройн бодлого (ЧОБ) -ыг хувьслын алгоритм (evolutionary algorithm (EA))-аар бодох аргыг судална. ЧОБ нь сүлжээнээс хамгийн цөөн тооны оройг устган, үлдэгдэл сүлжээний хамгийн том холбоост бүрдлийн (ХТХБ) хэмжээг өгөгдсөн L параметрээс бага байлгах бодлого юм. Сүүлийн жилүүдэд хийгдэж буй өгөгдөлд суурилсан судалгаагаар байгаль, нийгэм дэх сүлжээ (систем) нь бүлэг бүтэц (community structure)-тэй гэдгийг тогтоогоод байна. Энэ ажилд сүлжээний бүлэг бүтцийн мэдээллийг ЧОБ-д ашиглах шинэ аргыг танилцууллаа. Тодруулбал, бүлэг бүтцийн мэдээллийг генийн дүрслэлээр (representation) ашиглах хувьслын алгоритмыг зохиомжлов. ЧОБ-д өргөн ашиглагддаг зургаан бодит сүлжээн дээр алгоритмын ажиллагааг туршиж, Greedy1, Greedy2, Genetic algorithm гэсэн гурван аргатай харьцуулан, дэвшүүлж буй алгоритмын гүйцэтгэлийг үнэллээ. Дэвшүүлж буй алгоритм том сүлжээн дээр 10-30 дахин богино хугацаанд, 2 өгөгдөл дээр давуу шийд гаргаж байгааг туршилтын үр дүн харуулав.
Comparación de indicadores microbiológicos en sistemas de cultivo de tomate convencional o hidropónico
Authors: Wittmann Vega Viviana , Davidovich-Young Gabriela , Wong-González Eric , Montero Barrantes Manuel
Published: October 2023

Introducción: El consumo de tomate fresco ha ido en aumento a través de los años y los sistemas de cultivo (convencional o hidropónico), las prácticas de cosecha y poscosecha, el agua de riego y los contenedores pueden incidir sobre su calidad microbiológica. Objetivo: Comparar la calidad microbiológica de la fruta cultivada o cosechada, del agua de riego y de los contenedores de cosecha en dos fincas de producción de tomate (convencional e hidropónica). Métodos: Realizamos tres muestreos a cada finca (repeticiones), tomando, en cada repetición, 3 tomates de cada tipo que conformaron una muestra compuesta, 50 ml de agua de riego e hisopando 50cm2 de la superficie de tres contenedores de cosecha (muestra compuesta). Determinamos los indicadores microbiológicos de recuento total aerobio mesófilo, recuento de hongos filamentosos y levaduras, coliformes totales, coliformes termotolerantes y E. coli. Además, analizamos la presencia de Listeria monocytogenes en los frutos. Aplicamos pruebas de t-student a un nivel de significancia del 5%. Resultados: Los recuentos total aerobio mesófilo y hongos filamentosos y levaduras del tomate hidropónico fueron significativamente menores que en el tomate convencional, mientras que no hubo diferencia en los recuentos de coliformes totales y E. coli, además L. monocytogenes estuvo ausente en todas las muestras. El recuento total aerobio mesófilo fue mayor en los contenedores de cosecha de la finca convencional.  En ambas fincas el agua de riego no se consideró fuente de contaminación pues tuvo niveles muy bajos de coliformes totales, coliformes termotolerantes y E. coli.  Finalmente, se presume un control adecuado en las fincas durante la cosecha, al no haber encontrado diferencia en los indicadores microbiológicos entre el tomate cultivado y el cosechado. Conclusión: Los tomates hidropónicos presentan mayor probabilidad de tener un mejor perfil microbiológico y mayor vida útil en comparación con los tomates cultivados de forma convencional, evidenciando la importancia del control ambiental y la limpieza y desinfección de todos los insumos utilizados en los procesos de cultivo, cosecha y poscosecha.
Uso racional de antihistamínicos en enfermedades alérgicas y respiratorias
Authors: S Pury , R J Saranz , N A Lozano , G Alegre , P Visconti , L Lozano
Published: October 2023

La histamina es el mediador químico principal producido por el mastocito ante estímulos inmunológicos yno inmunológicos que interviene en la producción de síntomas de broncoespasmos, rinitis, urticaria yanafilaxia. Los antihistamínicos H1 son fármacos ampliamente indicados por pediatras y clínicos en supráctica médica desde hace más de 50 años. El desarrollo de anti-H1 de segunda generación y susmetabolitos han contribuido a su uso más eficaz y con alta seguridad terapéutica.Este artículo tiene el objetivo revisar la farmacología e indicaciones clínicas más relevantes a fin decontribuir a la indicación adecuada y racional de los antihistamínicos H1.
Reduced kinetic mechanism for modeling high-temperature ignition and flames for n-pentanol
Authors: Tiburcio-Cortés Jaime , Prince Juan , Treviño César
Published: October 2023

N-pentanol emerges as a promising substitute for fossil fuel due to its
potential in reducing greenhouse gas emissions. This work presents a
reduced combustion mechanism for modeling high-temperature ignition
(T>1000 K) and flames for n-pentanol/air mixtures. The
model comprises only 64 species and 282 chemical reactions. As we know,
this is the first comprehensive study to include all available
experimental data for these phenomena and this specific fuel/oxidizer
mixture, reported in the literature. Our approach involves coupling a
detailed sub-mechanism for n-pentanol to the San Diego mechanism, a
reduced scheme for C1-C4 hydrocarbons, followed by systematic reduction
using sensitivity analysis and steady-state approximation. We
quantitatively assessed the agreement between experimental data and
simulation results using deviation or error indicators, along with
graphical comparisons. Remarkably, the ignition delay times, and flame
speeds calculated using the reduced kinetic model exhibit a high
agreement regarding the experimental data reported in the literature.
A comparative study of left atrial appendage wall velocity (LAAWV) in correlation to LV ejection fraction, LV global longitudinal strain (GLS), E/e’, and NT pro-BNP in ischemic and non-ischemic heart failure.
Authors: Bharali Abhijit , Tewari Satyendra , khare Harshit , SAHU ANKIT , Khanna Roopali , Kumar Sudeep , Garg Naveen , Kapoor Aditya
Published: October 2023

Background: Left atrial appendage (LAA) function assessment is
often overlooked in patients with heart failure and reduced ejection
fraction (HFrEF), regardless of its etiology (ischemic or non-ischemic
cardiomyopathy). With trans-thoracic tissue doppler echocardiographic
(TDE), we compared LAA wall velocity with the conventional
echocardiographic and biochemical parameters of heart failure by
evaluating LVEF, LV GLS, E/e’ and serum NT pro-BNP level.
Methods and Results: We evaluated 154 stable HFrEF patients
with LVEF ≤ 40%. The mean age was 55.71 ± 12.48 years, with 59.09%
being male and 40.91% female. Among them, 77.27% had dilated
cardiomyopathy (DCMP), and 22.72% had ischemic cardiomyopathy (ICMP).
The mean LVEF was 29.87 ± 5.8, LV GLS was -8.46 ± 2.74, mitral E/e’ was
13.33 ± 2.74, and LAA wall velocity was 14.26 ± 5.56. The mean NT
pro-BNP level was 980.51 ± 611.77. Correlation analysis showed that LAA
wall velocity significantly correlated with LVEF (r = 0.634, p
< 0.001), had an inverse correlation with LV GLS (r = -0.671,
p < 0.001), mitral E/e’ (r = -0.756, p < 0.001), and
NT pro-BNP (r = -0.659, p = 0.007). Conclusion: TDE LAA wall
velocity is a valuable and feasible method for evaluating HFrEF
patients. Lower LAA wall velocity is associated with reduced LVEF,
impaired LV GLS, elevated left ventricular filling pressure (E/e’), and
higher NT pro-BNP levels.
Comparison of the conventional echocardiographic parameters with the global longitudinal strain of the left and right ventricle, in the low-dose anthracycline treatment in patients with the low CV risk.
Authors: Gorgiladze Nana , Gaprindashvili T. , Pagava Z. , Shavdia M. , Gogua E. , Gachechiladze L.
Published: October 2023

AbstractIntroduction/Purpose Breast cancer patients
undergoing chemotherapy are at risk of chemotherapy-induced
cardiovascular toxicity (CTR-CVT). The right ventricle (RV) may also be
susceptible to CTR-CVT and may exhibit symptoms of dysfunction before
the left ventricle. Our study aims to compare the effectiveness of
conventional echocardiographic parameters with the global longitudinal
strain techniques in patients receiving low-dose anthracycline treatment
and having low cardiovascular risk. Methods In a recent study,
28 women with low cardiovascular risk who underwent low-dose
anthracycline chemotherapy for breast cancer were assessed for cardiac
function using 2D echocardiography and speckle-tracking
echocardiography. The measurements included LVEF, RVS’, TAPSE, LVGLS,
and RVGLS. All patients had normal LVEF at the beginning of the study.
Cardiotoxicity was defined as a new decrease in LVEF by 10% or below
53%, and/or changes in LVGLS/RVGLS by 15%. Results Our study
found that the LVGLS decreased from -21.2%±2.1% to -18.6%±2.6%
(t-test = -4.116; df = 54, p=0.001). Similarly, the RVGLS decreased from
-25.2%±2.9% to -21.4%±4.4% (t-test = -3.82; df = 54, p=0.001).
However, the measurements of right ventricular systolic function (RVS),
tricuspid annular plane systolic excursion (TAPSE), and the left
ventricular ejection fraction (LVEF) were insignificant.
Conclusion(s) The study’s findings suggest that relatively new
imaging technique GLS measurements are more sensitive than conventional
echocardiographic parameters ( LVEF, TAPSE, RVS) for the detection of
myocardial damage and a potential decline in cardiac function at the
early stages of chemotherapy treatment. Moreover, RV-GLS is more
sensitive to these changes despite the dosage and regimen of the
chemotherapy.
Eye in the Sky: Hyperspectral Imaging for Sustainable Nitrogen Management in Vegetables
Authors: Gill Taqdeer , Townsend Philip A. , Wang Yi
Published: October 2023

Snap beans and kidney beans are poor nitrogen fixers and need nitrogen
(N) fertilizer. However, excessive application of N leads to groundwater
contamination. The traditional way of measuring crop nitrogen status is
destructive and time-consuming. The objective of this study was to
develop a tool that accurately predict the real-time crop nitrogen
status and the end-of season yield for optimizing fertilizer management.

The field trial was conducted in 2022 and 2023. Eight nitrogen
treatments were applied at 22 kg ha, 56 kg
ha, 84 kg ha, 112 kg
ha, 140 kg ha, 168 kg ha-1, 196
kg ha, 224 kg ha to three kidney
beans cultivars. Six nitrogen treatments were applied at 22 kg
ha, 56 kg ha, 84 kg
ha, 112 kg ha, 140 kg
ha, 168 kg ha to two snap beans
cultivars. Hyperspectral images (400 nm to 2500 nm) were collected on a
weekly basis. Top twenty bands along with genotype (cultivars),
environmental factors (temperature, precipitation, growing Degree Days),
management factors (nitrogen rate, days after planting, irrigation) were
used to train different machine learning algorithms including linear
regression, random forest, XG Boost, support vector machine and
k-nearest neighbors for predicting the nitrogen status and the final
yield.

Our results indicated that top twenty bands along with GEM performed the
best for predicting final yield (R as high as 0.82
and RMSE as low as 1.6). Our study demonstrated the potential capacity
of hyperspectral imaging and machine learning models to estimate crop
yield and nitrogen status.
Antropoceno:
Authors: Suliani Carla , Klanovicz Jó , Da Silva Claiton Marcio
Published: November 2023

O conceito de Antropoceno vem provocando debates relativos tanto à sua aceitação como uma era geológica quanto a uma disputa sobre seus significados. Partindo de uma perspectiva crítica, autores como Jason Moore, Anna Tsing, Donna Haraway, entre outros, chamam atenção para os limites do conceito ou propõem novas perspectivas de análise; nessa miríade interpretativa, a história e a historiografia do Antropoceno estão em constante revisão, incorporando e ressignificando elementos de análise. Este artigo busca situar o debate em torno do Antropoceno tanto em termos de análise histórica quanto de produção historiográfica até o momento. Finalmente, indica algumas perspectivas de análise empírica que vêm sendo construídas sobre o tema, principalmente no Brasil.
The Pornography Industry's Disinformation Campaign Against Addiction Recovery Resources
Authors:   The Reward Foundation, Mead Darryl
Published: October 2023

As pornography became increasingly popular online, many unsuspecting consumers reported adverse effects. These included sexual dysfunctions, such as lack of response with real partners, delayed ejaculation, erectile difficulties, and sexual compulsivity. Some pornography consumers began congregating in online self-help portals (forums and websites) to assist one another in quitting or reducing problematic pornography use. The popularity of the self-help resources and their potential to dampen the profits of a lucrative industry resulted in disinformation campaigns run by individuals connected to the pornography industry. In this article, I examine how a paper containing significant inaccuracies about the people organising the online recovery forums passed the peer-review process while failing to disclose the author’s conflicts of interest. The author of the case study has documented affiliations with a major pornography company, MindGeek (the owner of Pornhub). Somehow, it passed peer review, lending it a false halo of credibility. Pornography industry-connected individuals then repeatedly exploited it, for example, on social media and Wikipedia, to discredit pornography self-help recovery resources.
Å utforske velferdsobjektivering: Nav-ansattes erfaringer med samarbeid
Authors: Pedersen Linn-Marie Lillehaug
Published: November 2023

In this chapter, I show how I have applied the concept of objectivation to explore how frontline workers in the Norwegian Labor and Welfare Administration carry out and reflect on interprofessional collaboration in their work with youth. Institutional and political discourse on interprofessional collaboration motivates collaborative efforts across services. In this chapter, I describe the interaction between frontline workers’ experiences of interprofessional collaboration and the institutional conditions and procedures associated with interprofessional collaboration. I analyze nine semi-structured interviews with frontline workers in the Norwegian Labor and Welfare Administration. Applying objectivation as an analytical concept, I find that even though interprofessional collaboration occasionally can be useful and effective for the youth, the unquestioned understanding of interprofessional collaboration as positive also leads to the frontline workers subsuming the youths’ experiences.
Følelsesstyrt? Om styringsrelasjoner, følelser og tilgang til ulike ståsteder
Authors: Magnussen May-Linda , Steen-Johnsen Tale , Synnes Katrine Mayora
Published: November 2023

In this chapter, we explain the concept of ruling relations. We show how emotions and access to different standpoints have helped us see and explore objectification and ruling across three different research projects. The standpoints of our informants clearly differ from one another. While May-Linda’s and Tale’s standpoint informants are associate professors, Katrine’s standpoint informants are unemployed Polish men in precarious situations. While institutional texts contribute to reducing academics to “brain power”, such texts contribute to reducing the Polish migrants to “work force”. We argue that this objectification – among other things – produces feelings of shame when our informants are not able to live up to the generalized, objectified understandings of them. We argue that collective knowledge development processes – which are promoted in institutional ethnography – can turn our gazes outwards rather than inwards, and turn shame into irritation and anger, thus facilitating change. Not least, we argue that such processes can help us see that we are also contributing to objectification and ruling that have (more) problematic effects for others than ourselves, for example because objectification and ruling can also produce feelings of pride. That means that collective knowledge development can help us challenge ruling that is more problematic for others than for ourselves, and that may have many negative effects on the institutions we engage in.