bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Design and Synthesis of a New Ferroelectric Liquid Crystal Family.
Authors: WALBA D. M. , SLATER S. C. , THURMES W. N. , CLARK N. A. , HANDSCHY M. A. , SUPON F.
Published: May 2016

Examples (VII) of the title class or analogues obtained with (Vb) are synthesized in accordance with the scheme.
ChemInform Abstract: Variable‐Temperature Single‐Crystal ESR Study and Crystal Structure of [Cu(C6H15N3)2][Cu(CN)3] . 2 H2O at 110 and 293 K. Static and Dynamic Jahn‐Teller Distortions in the CuN6 Polyhedron,
Authors: CHAUDHURI P. , ODER K. , WIEGHARDT K. , WEISS J. , REEDIJK J. , HINRICHS W. , WOOD J. , OZAROWSKI A. , STRATEMAIER H. , REINEN D.
Published: May 2016

The title complex is precipitated after addition of a small amount of KCN to an aqueous solution of CuCl2 ‐ 2 H2O and the triaza ligand in equimolar amounts at room temperature.
ChemInform Abstract: Counterligand Dependence of Charge Distribution in Copper‐Quinone Complexes.
Authors: BUCHANAN R. M. , WILSON‐BLUMENBERG C. , TRAPP C. , LARSEN S. K. , GREENE D. L. , PIERPONT C. G.
Published: May 2016

Samples prepared in a hydrated medium and recrystallized from CH2Cl2 form the monomeric compound (I) with a four‐coordinate square planar Cu ion.
ChemInform Abstract: Electrochemical Evidence for a Three‐Center, Three‐Electron Agostic Interaction in Tungstenocene Dialkyl Cations and Estimation of the Magnitude of the Interaction.
Authors: ASARO M. F. , COOPER S. R. , COOPER N. J.
Published: May 2016

Cyclic voltammograms in acetonitrile of the tungstenocene compounds (I)‐(III) exhibit a reversible one‐electron oxidation between ‐450 and + 125 mV 19 vs. SCE.
ChemInform Abstract: Free‐Radical Chemistry. Part 7. Additions to Hexafluoro‐2‐butyne.
Authors: CHAMBERS R. D. , JONES C. G. P. , SILVESTER M. J.
Published: May 2016

The radical‐induced reaction of the aldehyde (I) or the alcohols (VI) with hexafluoro‐2‐butyne (II) yields the products (III)‐(V), (VII), and (VIII) as shown in the reaction scheme.
ChemInform Abstract: Cyclic Derivatives from Alkoxybenzohydrazides. Synthesis of Pyrazoles, Pyrroles and Triazol‐5‐ones of Pharmaceutical Interest.
Authors: MAZZONE G. , PUGLISI G. , CORSARO A. , PANICO A. , BONINA F. , AMICO‐ROXAS M. , CARUSO A. , TROMBADORE S.
Published: May 2016

Title compounds of type (III), (V) and (VIII) are synthesized as shown in the scheme and screened for their biological activity.
ChemInform Abstract: Polycyclic Hydroxyquinones. Part 24. Diels‐Alder Reactions of 5‐Amino‐8‐hydroxy‐1,4‐naphthoquinone.
Authors: FARINA F. , PAREDES M. C. , STEFANI V.
Published: May 2016

The Diels‐Alder reaction of quinones (I) with (IV) and (VI) yields the adducts (V) and (VII), resp., giving (II) and (III) on mild alkaline air oxidation [due to partial hydrolysis under these conditions, (IIc)‐(IIe) and (IIIc)‐(IIIe) are prepared by derivatization of (IIa) and (IIIa) using standard procedures].
ChemInform Abstract: Synthesis and Biological Activity of Carboxylic Acids with Sulfur Containing Groups in β‐Positions.
Authors: ZNAMENSKII V. V. , EFREMOV A. D. , BYSTROVA V. M. , VASIL'EVA T. P. , KIL'DISHEVA O. V.
Published: May 2016

Die Ringöffnung der cyclischen Sulfinsäureanhydride (I) mit Nucleophilen führt zu den β‐Sulfinoamiden (III) und (IV), dem Ester (V) oder zu den Sulfinocarbonsäure‐Salzen (VI).
ChemInform Abstract: Novel Heterocycles: Tetrazinodi(heteroarenes), Synthesis and Structure.
Authors: EICHENBERGER T. , BALLI H.
Published: May 2016

The title compounds (IV), (VII), (X), (XIII), (XVI) and (XVII) are obtained in a two‐step Synthesis by N‐aminating heterocyclic compounds such as (I), (V), (VIII), (XI) substituted with a leaving group and by treating the products with an organic or inorganic base.
ChemInform Abstract: Liquid‐Crystalline Solvents as Mechanistic Probes. Part 21. Control of Norrish II 1,4‐Biradical Reactivity by the Phase and Molecular Dimensions of an Ordered Solvent.
Authors: ZIMMERMANN R. G. , LIU J. H. , WEISS R. G.
Published: May 2016

The biradicals (II) and (III) are generated by irradiation in crystalline‐, smectic B‐like‐, nematic‐, and isotropic‐phase solution of (IX).
ChemInform Abstract: Azo Anions in Synthesis. Part 1. t‐Butylhydrazones as Acyl‐Anion Equivalents.
Authors: BALDWIN J. E. , ADLINGTON R. M. , BOTTARO J. C. , KOLHE J. N. , PERRY M. W. D. , JAIN A. U.
Published: May 2016

The conversion (IIId) ‐ (VIII) exemplifies the use of the title compounds (III) [prepared from (I)] as acyl‐anion equivalents: anions of type (IV) generated from aldehydes (IIId)‐(IIIg) are treated with an electrophile such as (V) to yield (VI); subsequent tautomerization [‐ (VII)] and hydrolysis provides the target compound (VIII).
ChemInform Abstract: Enhanced cis‐Selectivities in Olefination Reactions Employing Ylids with Modified "Stationary Groups".
Authors: SCHAUB B. , JEGANATHAN S. , SCHLOSSER M.
Published: May 2016

Die aus den Triarylphosphanen (I) mit den Alkylhalogeniden (II) erhaltenen Phosphoniumsalze (III) liefern mit NaNHg die Ylide (IV).
ChemInform Abstract: Reductive Coupling of α,β‐Unsaturated Ketones. Part 3. (+)‐Pulegone: An Example of Umpolung.
Authors: PONS J.‐M. , SANTELLI M.
Published: May 2016

(+)‐Pulegone (I) is reduced yielding the isomeric menthones (II) and (III).
ChemInform Abstract: Excited‐State Rearrangements of 1,3‐ and 1,5‐Dienes in a Radio Frequency Plasma.
Authors: MILLER L. L. , MIZOBUCHI Y.
Published: May 2016

The products obtained by distilling 1,3‐ and 1,5‐dienes through an inductively coupled radio frequency plasma are described.
ChemInform Abstract: Reaction of Tetrafluoroethene Oligomers. Part 5. Some Reactions of Perfluoro[(1‐ethyl‐1‐methylpropyl)(1‐methylpropyl)]keten.
Authors: COE P. L. , SELLARS A. , TATLOW J. C. , FIELDING H. C. , WHITTAKER G.
Published: May 2016

Reaction of the title keten (IV) with methanol (III) produces an inseparable mixture of theproducts (I) and (II), which can be treated with sodium alkoxide to yield pure (I).
ChemInform Abstract: Methionine as Precursor for the Enantioselective Synthesis of α‐Branched Vinylglycines and of Other Amino Acids.
Authors: WEBER T. , AESCHIMANN R. , MAETZKE T. , SEEBACH D.
Published: May 2016

The title compound (I) is converted to the heterocycles (II) by means of previously described procedures [crystal structure of (IIc): space group P2/n with Z=4].
ChemInform Abstract: Octaphenyl[4]radialene.
Authors: IYODA M. , OTANI H. , ODA M. , KAI Y. , BABA Y. , KASAI N.
Published: May 2016

An efficient one‐pot synthesis of the sterically crowded title compound (III) [+ by‐product (IV)] Starting from the corresponding Li‐carbenoid of the ethylene (I) via the ate‐type complex (II) is reported.
ChemInform Abstract: Diels‐Alder Approach to Highly Functionalized Tertiary α‐Hydroxy Ketones: A Novel Route to the Hexahydrobenzofuran Portion of the Avermectins and Milbemycins.
Authors: IRELAND R. E. , OBRECHT D. M.
Published: May 2016

The dienophiles (III) are synthesized from the threonates (II) which, in turn, are accessible from the known ascorbic acid derivative (I) in a multi‐step sequence.
ChemInform Abstract: Hydroxyadamantanes and Their Biological Activity.
Authors: KLIMOVA I. V. , LAVROVA L. N. , ZAITSEVA N. M. , PYATIN B. M. , MOROZOV I. S. , BYKOV N. P. , KHRANILOV A. A.
Published: May 2016

Durch Oxidation mit konzentrierter Salpetersäure und Schwefelsäure werden die 2‐ bzw. 1‐Aminoadamantane (I) und (III) zu den Hydroxyadamantanen (II) bzw. (IV) hydroxyliert.
ChemInform Abstract: A Facile Route to (±)‐2‐Arylpropanoic Acids.
Authors: HIYAMA T. , INOUE M. , SAITO K.
Published: May 2016

The aryl methyl ketones (Ia) and (Ib) are converted into the racemic 2‐arylpropanoic acids ibuprofen (IVa) and naproxen (IVb) respectively via the cyanohydrin acetates (II) and the nitriles (III).
ChemInform Abstract: Interaction Between Non‐Conjugated Chromophores. Part.25. Diels‐Alder Regioselectivity Controlled by Remote Substituents.
Authors: METRAL J.‐L. , LAUTERWEIN J. , VOGEL P.
Published: May 2016

1. The synthesis of the methylidene compounds (I) and (II) is reported: The ester (IVa) [obtained from the anhydride (IIIa)] is transformed to the mesylate (IVc) via (IVb); subsequent elimination reaction furnishes (Ia) which is converted to (Ib) and (Ic) by standard reactions.
ChemInform Abstract: Pyrrole Studies. Part 34. Synthesis of 1,2‐Di(2‐pyrrolyl)ethenes and Related Compounds.
Authors: HINZ W. , JONES R. A. , ANDERSON T.
Published: May 2016

The 1,2‐di(2‐pyrrolyl)ethenes (III) and the 2‐styrylpyrroles (VI) are synthesized by Wittig reaction.
ChemInform Abstract: Synthesis and Hypoglycemic Activity of N‐Acyl‐5‐methoxytryptamines.
Authors: GRIN L. M. , KHLAPONINA L. N. , PIVNENKO N. S. , SELICHENKO A. G. , BRUTOV B. D.
Published: May 2016

Die im Titel genannten Verbindungen (III) werden aus 5‐Methoxy‐tryptamin (I) und den Säurechloriden (II) dargestellt und auf ihre hypoglykämische Wirkung an der Ratte untersucht.
ChemInform Abstract: Antiinflammatory 2,3‐Dihydro‐1H‐pyrrolizines. Part 10. 6,7‐Diaryl Substituted 1‐and 3‐Pyrrolizinones (1‐DAPON and 3‐DAPON).
Authors: DANNHARDT G. , STEINDL L.
Published: May 2016

Die Selendioxid‐Oxidation des Dihydropyrrolizins (I) liefert neben geringen Mengen des Diselenids (III) das Pyrrolizinon (II).
ChemInform Abstract: Enantiospecific Synthesis of (R)‐(+)‐α‐Lipoic Acid from D‐Glucose.
Authors: RAO A. V. R. , GURJAR M. K. , GARYALI K. , RAVINDRANATHAN T.
Published: May 2016

Ausgehend von dem literaturbekannten Glykosid (Ia) wird entsprechend den im Formelschema skizzierten Umsetzungen die im Titel genannte Säure (VII) synthetisiert.
ChemInform Abstract: Studies on Histaminergic Compounds. Part 5. VUF 8405 (Ib), a Potent and Relatively Easy Accessible Analogue of the H2‐Agonist Impromidine (Ia).
Authors: STERK G. J. , VAN DER GOOT H. , TIMMERMAN H.
Published: May 2016

The title compound (Ib) is shown to possess about 25% of the potency of the H2‐agonist impromidine (Ia).
ChemInform Abstract: Biological Action of New Iminium Compounds on Selected Bacteria and Fungi.
Authors: PERNAK J. , KRYSINSKI J. , SKRZYPCZAK A.
Published: May 2016

Die im Titel genannten Verbindungen (III) entstehen aus den entsprechenden Imidazolen (I) und den Chlormethylthioethern (II).
ChemInform Abstract: Synthesis of Fatty 2‐Oxazolines from Fatty Methyl 2,3‐Epoxy Ester.
Authors: ANSARI M. H. , AHMAD M.
Published: May 2016

Die Umsetzung des Epoxycarbonsäureesters (I) mit den Nitrilen (II) in Gegenwart von BF3‐Etherat (III) liefert Gemische aus den Oxazolidincarbonsäureestern (IV), dem Dihydroxycarbonsäureester (V) und den Acylaminohydroxycarbonsäureestern (VI).
ChemInform Abstract: Antiepileptic and Analgesic Activity of Structures Related to Hydantoins: Study of Some Dioxothiadiazabicyclooctanes.
Authors: PAPON M.‐H. , REFOUVELET B. , BASTIDE P. , BASTIDE J. , TRONCHE P.
Published: May 2016

The title compounds (III) are synthesized as described and screened for their biological activity.
ChemInform Abstract: Syntheses and in vitro Antimicrobial Evaluation of Some Benzimidazol‐2‐ ylmethylthioureas, Benzimidazol‐2‐ylacetylthiosemicarbazides and Products of Their Condensation with Monochloroacetic Acid.
Authors: RIDA S. M. , LABOUTA I. M. , SALAMA H. M. , GHANY Y. S. A. , EL‐GHAZZAUI E. , KADER O.
Published: May 2016

Das aus dem Carbonsäureester (I) erhältliche I‐Iydrazid (II) addiert die Isothiocyanate (III) zu den Acylthiosemicarbaziden (IV), die mit Chloressigsäure (V) zu den Thiazolidindionacylhydrazonen (VI) cyclisieren.
ChemInform Abstract: Alkylation Reactions of Anions Derived from 2‐Benzenesulphonyl Tetrahydropyran and Their Application to Spiroketal Synthesis.
Authors: LEY S. V. , LYGO B. , STERNFELD F. , WONNACOTT A.
Published: May 2016

The benzenesulphonyl tetrahydropyran (I) can be obtained from 3,4‐dihydro‐2H‐pyran or 2‐methoxytetrahydropyran with benzenesulphinic acid.
ChemInform Abstract: 5‐Aryl‐3‐isopropyl‐6,6‐dimethyl‐2‐cyclohexenones and 2,6‐Diaryl‐tetrahydro‐3,3‐dimethyl‐4H‐pyran‐4‐ones.
Authors: UNTERHALT B. , WEYRICH K.
Published: May 2016

Bei der Reaktion der Benzaldehyde (I) mit 3‐Methyl‐ 2‐butanon (II) entsteht zumeist ein Produktgemisch aus (III)‐(V), z.Tl. wird nur eines der drei Produkte isoliert.
ChemInform Abstract: Reduction of Dinitro‐Compounds with Titanous Chloride: A Regiospecific Reduction of 6,8‐Dinitroquinoline.
Authors: SCHOFIELD J. , SMALLEY R. K. , SCOPES D. I. C.
Published: May 2016

6,8‐Dinitroquinoline (I) is reduced regiospecifically by Ti(III) Chloride, yielding (II).
ChemInform Abstract: A Facile Synthesis of 7‐Halo‐5H‐indeno[1,2‐b]pyridines and ‐pyridin‐5‐ones.
Authors: DUPRIEST M. T. , SCHMIDT C. L. , KUZMICH D. , WILLIAMS S. B.
Published: May 2016

Aus dem Fluorpicolin (I) und den Aryllithiumverbindungen (II) werden die Arylpicoline (III) hergestellt, die durch Oxidation zu (IV) und anschließende Cyclisierung in die Ketone (V) übergeführt werden.
ChemInform Abstract: Synthesis and Pharmacological Study of Some 3‐(Pyrazol‐5‐yl)‐quinazolin‐ 4(3H)‐ones.
Authors: PLESCIA S. , BAJARDI M. L. , RAFFA D. , DAIDONE G. , MATERA M. , CARUSO A. , AMICO‐ROXAS M.
Published: May 2016

The compounds (Va) are prepared as shown in the scheme and screened for analgesic, antiinflammatory, and antipyretic activity as well as for acute toxicity.
ChemInform Abstract: Facile Synthesis of Fluorine Containing Imidazo[1,2‐b][1,2,4]triazines through α‐Oxo‐N‐aryl‐α‐arylethanehydrazonoyl Bromides.
Authors: JOSHI K. C. , PATHAK V. N. , SHARMA S.
Published: May 2016

The imidazo triazine derivatives (V) are synthesized as shown in the reaction scheme. Their mass spectra are discussed in detail.
ChemInform Abstract: Synthesis of Bi‐ and Tricyclic Mesoionic [1,2,4,6]Thiatriazine‐1,1,3‐ trioxides.
Authors: KANG J. S. , OH D. Y.
Published: May 2016

Die N‐substituierten Aminoheterocyclen (I), (IV) und (VIII) reagieren mit dem N‐Chlorsulfonylcarbamat (II) bzw. Chlorsulfonylisocyanat (VI) zu den im Titel genannten Verbindungen (III), (V), (VII) und (IX).
ChemInform Abstract: New Synthetic Routes to Fully Unsaturated 1,4‐Benzodiazepines from Quinolyl Azides.
Authors: SASHIDA H. , FUJII A. , SAWANISHI H. , TSUCHIYA T.
Published: May 2016

Die Photolyse der 4‐Azidochinoline (I) in Gegenwart von Natriummethanolat führt zu den instabilen 1H‐1,4‐Benzodiazepinen (II), die basenkatalysiert zu den stabilen 3H‐Derivaten (III) tautomerisieren.
ChemInform Abstract: Synthesis and X‐Ray Crystallographic Characterization of a (1,3,5)Cyclophane with Three Amide N‐H Groups Surrounding a Central Cavity. A Neutral Host for Anion Complexation.
Authors: PASCAL R. A. JUN. , SPERGEL J. , VAN ENGEN D.
Published: May 2016

The tris‐carboxylic acid (Ia) is transformed into the acid chloride (Ib). The tris‐bromomethyl derivative (Ic) is converted into the triamine (Id).
ChemInform Abstract: A Facile and General, One‐Pot Synthesis of 2‐Oxoalkane Phosphonates from Diethylphosphonocarboxylic Acid Chlorides and Organometallic Reagents.
Authors: COUTROT P. , GHRIBI A.
Published: May 2016

The 2‐diethylphosphonoalkanoic acids (II) are prepared by metallation and subsequent carboxylation of the diethyl phosphonates (I).
ChemInform Abstract: Tetrahedral Lewis Base Adducts of an Acyl. Preparation and X‐Ray Structure of the Pyridine Adduct (η5‐C5Me5)Cl3Ta[η2‐ OC(SiMe3)(NC5H5)].
Authors: ARNOLD J. , TILLEY T. D. , RHEINGOLD A. L.
Published: May 2016

The Ta silaacyl complex (II) reacts with pyridine to give the pyridine 1 :1 adduct (I) which is characterized by 1H NMR and IR spectroscopic data, and X‐ray structural analysis (spacegroup P2′/n, Z=4).
ChemInform Abstract: Stereochemistry and Metal‐Centered Rearrangements of Eight‐Coordinate Niobium(V) and Tantalum(V) Dithiocarbamates and Monothiocarbamates.
Authors: WEIR J. R. , FAY R. C.
Published: May 2016

By reaction of the metal pentahalides with anhydrous sodium salts of the ligands in CH2Cl2 the eight‐coordinate Nb(V) and Ta(V) complexes (I)‐(III) are prepared.
ChemInform Abstract: One‐ and Two‐Electron Photooxidation of a Molybdenum(III) Thiocyanate Complex.
Authors: YAO Q. , MAVERICK A. W.
Published: May 2016

F1ash irradiation(350 ‐ 450 nm) of solutions of (I) and several electron acceptors leads to (II).
ChemInform Abstract: Structure and Dynamic Behavior in Solution of Binuclear Nickel(II) Face‐to‐Face Complexes with Bis(cyclidene) Ligands.
Authors: HOSHINO N. , GOLDSBY K. A. , BUSCH D. H.
Published: May 2016

NMR studies of the dinickel(II) complexes (I) with macrocyclic bis(cyclidene) ligands reveal a dynamic molecular motion in solution.
ChemInform Abstract: Convenient Synthesis and Properties of (R4N)2(Ni(SAr)4) (Ar: C6H5, p‐ C5H4Cl, p‐ C6H4CH3, and m‐ C6H4Cl) and the Structure of Tetraethylammonium Tetrakis(p‐chlorobenzenethiolato)nickelate(II).
Authors: ROSENFIELD S. G. , ARMSTRONG W. H. , MASCHARAK P. K.
Published: May 2016

The soluble nickel thiolates (III), prepared as shown, are not obtained in protic solvents, where only insoluble polymeric materials are formed.
ChemInform Abstract: Solution Chemistry of Rhodium Trifluoroacetate in the Presence of Phosphorus Donors.
Authors: TELSER J. , DRAGO R. S.
Published: May 2016

31P{1H} and 19F NMR studies on the complexes of the general type (I) are described.
ChemInform Abstract: Conversion of the μ‐Ketene Ligand in [PPN][Os3(CO)10(μ‐I)(μ‐CH2CO)] into Enolate, Acyl, and Vinyl Ligands.
Authors: BASSNER S. L. , MORRISON E. D. , GEOFFROY G. L. , RHEINGOLD A. L.
Published: May 2016

The reactivity of the coordinated ketene ligand in the anionic Cluster compound (I) is studied.
ChemInform Abstract: Binuclear Complexes of Platinum(II) and Palladium(II) with Bis(isopropylphosphino)methane and Related Ligands.
Authors: RADECKA‐PARYZEK W. , MCLENNAN A. J. , PUDDEPHATT R. J.
Published: May 2016

The title ligand (II) is prepared from the chloro analogue (I) as shown.
ChemInform Abstract: Oxidative‐Addition Reactions of Potassium Tetrachloroplatinate(II) with N,N‐Dialkylacetamides Under Mild Reaction Conditions. Synthesis of cyclic [cis‐Pt(CH2N(CH3)C(CH3)O)2‐trans‐Cl2] and [trans‐Pt(OC(CH3)N(CH3)2)2‐trans‐Cl2].
Authors: ROAT R. M. , YOLLES S. , RHEINGOLD A. L.
Published: May 2016

On combining potassium tetrachloroplatinate(II) with N,N‐dimethylacetamide(DMA), at 60 ° C, an oxidative‐addition, ortho‐metalation reaction occurs and gives the Pt(IV) title complex (I) and small amount of the trans‐Pt(II) product (II).
ChemInform Abstract: Cyclitol Epoxides. Synthesis of Methylsulfonyl Derivatives of Inositol Oxiranes.
Authors: CADENAS R. A. , AGUILAR G. J. , GELPI M. E.
Published: May 2016

Ausgehend von dem Tetramesylat (I) werden, wie im Formelschema angegeben, die Epoxide (II), (IV) und (V) sowie das Diepoxid (VI) in Form der Racemate synthetisiert.
ChemInform Abstract: An Unusual Behavior of Methyl or Benzyl 3‐Azido‐5‐O‐benzoyl‐3,6‐dideoxy‐α‐L‐talofuranoside with (Dimethylamino)sulfur Trifluoride. Migration of the Alkoxyl Group from the C‐1 to the C‐2 Position.
Authors: HASEGAWA A. , GOTO M. , KISO M.
Published: May 2016

Ausgehend von der L‐Idofuranose (Ia) wird über die geschützten Derivate (Ib)‐(Id) zunächst das Azid (II) dargestellt, das wie angegeben zu den im Titel genannten Glykosiden (III) umgesetzt wird.
ChemInform Abstract: The Preparation of O‐Trifluoromethyl Carbohydrates.
Authors: TRAINOR G. L.
Published: May 2016

Aus den Trifluormethan‐sulfonsäureestern (Ib) und (IVa) werden unter den angegebenen Bedingungen die Trifluormethylether (Ic) und (IVb) erhalten; als Nebenprodukte entstehen die entsprechenden 6‐Desoxy‐6‐Fluor‐Verbindungen (II) bzw. (V).
ChemInform Abstract: 1‐Propenyl 4,6‐O‐Benzylidene‐β‐D‐mannopyranoside‐2,3‐cyclic Sulfate: A Substrate for the Synthesis of [F‐18] 2‐Deoxy‐2‐fluoro‐D‐glucose.
Authors: TEWSON T. J. , SODERLIND M.
Published: May 2016

Entsprechend den im Formelschema skizzierten Umsetzungen wird das im Titel genannte cyclische Sulfat (VII) synthetisiert.
ChemInform Abstract: On the Stereoselectivity of Fluorine and Acetylhypofluorite Additions to Glycals: The Synthesis of 2‐Deoxy‐2‐fluorohexoses.
Authors: SATYAMURTHY N. , BIDA G. T. , PADGETT H. C. , BARRIO J. R.
Published: May 2016

Die Fluorierung der Glucale (I) führt mit von den Reaktionsbedingungen abhängigen Ausbeuten zu den 2‐Fluorhexosen (II) und (III).
ChemInform Abstract: Further Development of Oligoribonucleotide: Bis(tributyltin)oxide as a Reagent for Removal of the Internucleotidic Phenylthio Group via the Phosphotriester Approach.
Authors: TANIMURA H. , SEKINE M. , HATA T.
Published: May 2016

The synthesis of the decanucleotide (X) can be achieved using a successful deprotection method by treatment with the tin species (IX) for the internal phenylthiogroup. The fully protected precursor of (X) is synthesized starting from the units (Ia) and (Ib) as shown in the scheme (usual reaction conditions).
ChemInform Abstract: 5,6‐O‐Benzylidene Derivatives of Dehydro‐L‐ascorbic Acid and Dehydro‐D‐isoascorbic Acid Osazones.
Authors: EL ASHRY E. S. H. , EL KILANY Y. , SINGAB F.
Published: May 2016

Die aus den Osazonen (I) hergestellten Benzylidenverbindungen (II) lagern sich unter basischen Bedingungen zu den Pyrazoldion‐Derivaten (III) um. Aus diesen werden die Ester (IV) für spektroskopische Untersuchungen synthetisiert.
ChemInform Abstract: Modification of Catalytic Activity of Hydrolytic Enzymes with Fluorine‐ Containing Molecules.
Authors: KITAZUME T. , MURATA K. , IKEYA T.
Published: May 2016

The fluorine‐containing enzymes (III) and (V) are synthesized by reacting enzymes of microbial origin with hexafluoropropene (II) and 2‐trifluoromethyl propenoic acid chloride (IV).
ChemInform Abstract: Studies on β‐Lactam Antibiotics for Medicinal Purpose. Part 16. Synthesis of 7β‐Amino‐3‐substituted Methyl‐3‐cephem‐4‐carboxylic Acids.
Authors: SADAKI H. , IMAIZUMI H. , INABA T. , HIRAKAWA T. , MUROTANI Y. , SAIKAWA I.
Published: May 2016

Ausgehend von β‐Aminocephalosporansäure (I) werden mit den verschiedenen Phenolen und Heterocyclen (II) die entsprechenden Derivate (III) bzw. mit den Nitrilen (IV) die Amide (V) hergestellt.
ChemInform Abstract: Total Synthesis of U‐71,184, a Potent New Antitumor Agent Modeled on CC‐1065.
Authors: WARPEHOSKI M. A.
Published: May 2016

The Synthesis of (VIII), an antitumor agent, is described.
ChemInform Abstract: Synthesis and Structure Elucidation of Merucathinone and Synthesis of Cathinone. Constituents of Catha edulis Forsk.
Authors: WOLF J.‐P. , PFANDER H.
Published: May 2016

The title compounds are synthesized nearly without racemization starting from the L‐alanine derivative (I) with protected amino group. They are isolated as their salts (IV) (yield given in g) and (VII) which are more stable than the free amines.
ChemInform Abstract: The Enantioselective Microbial Reduction of Methyl (±)‐5‐Chloro‐2‐oxobicyclo[2.2.1]heptane‐7‐anti‐carboxylate.
Authors: STIBOR I. , VESELY I. , PALECEK J. , MOSTECKY J.
Published: May 2016

The optical resolution of the racemic title compound (I) can be performed in two different manners.
ChemInform Abstract: Crystal Growth of Incommensurate Members of 2H‐Hexagonal Perovskite Related Oxides: Ba4MzPt3‐zO9 (M: Co, Ni, Cu, Zn, Mg, Pt).
Authors: Ferreira Timothy , Morrison Gregory , Yeon Jeongho , zur Loye Hans‐Conrad
Published: May 2016

Millimeter sized crystals of the title compounds (z = 0.6—1.2) are grown from molten K2CO3 fluxes using MnCO3, CoCO3, NiO, CuO, ZnO, MgO, and Pt as doping materials (alumina crucible, 1150 °C, 10 h, 91—99% yield).
ChemInform Abstract: Three Keggin‐Type Transition Metal‐Substituted Polyoxometalates as Pure Inorganic Photosensitizers for p‐Type Dye‐Sensitized Solar Cells.
Authors: Guo Xiang‐Wei , Li Jian‐Sheng , Sang Xiao‐Jing , Chen Wei‐Lin , Su Zhong‐Min , Wang En‐Bo
Published: May 2016

The polyoxometalates (Bu4N)8Na2 [SiW9O37{Co(H2O)3}] ·11H2O (I), (Bu4N)4 [(SiO4) W10MnIII2O36H6] ·1.5MeCN·2H2O (II), and (Bu4N)3.5H5.5 [(SiO4) W10MnIII/IV2O36] ·10H2O·0.5MeCN (III) are prepared according to the literature and explored as pure inorganic dye photosensitizers for p‐type DSSCs.
ChemInform Abstract: Tailor‐Made Ruthenium‐Triphos Catalysts for the Selective Homogeneous Hydrogenation of Lactams.
Authors: Meuresch Markus , Westhues Stefan , Leitner Walter , Klankermayer Juergen
Published: May 2016

The novel catalyst (RUT) shows increased activity and selectivity and facilitates the hydrogenation of challenging lactams.
ChemInform Abstract: Chiral Cobalt(III) Complexes as Bifunctional Broensted Acid‐Lewis Base Catalysts for the Preparation of Cyclic Organic Carbonates.
Authors: Rulev Yuri A. , Larionov Vladimir A. , Lokutova Anastasia V. , Moskalenko Margarita A. , Lependina Ol'ga L. , Maleev Victor I. , North Michael , Belokon Yuri N.
Published: May 2016

The catalyst is recycled and reused in two additional catalytic cycles without loss of its activity.
ChemInform Abstract: Design and Synthesis of Ruthenium(II) OCO Pincer Type NHC Complexes and Their Catalytic Role Towards the Synthesis of Amides.
Authors: Nirmala Muthukumaran , Viswanathamurthi Periasamy
Published: May 2016

New Ru(II) complexes bearing bis‐phenolate‐N‐heterocyclic carbene ligands [cf.
ChemInform Abstract: Palladium‐Catalyzed Double Ullmann Reaction: An Approach Towards Tetraphenylenes.
Authors: Li Xin , Han Jian‐Wei , Wong Henry N. C.
Published: May 2016

Starting from 2,2′‐diiodobiaryls a scalable synthesis of tetraphenylenes is developed delivering the products in 13‐51% yields.
ChemInform Abstract: Triphenylphosphine/Triethylamine‐Mediated Decarboxylation of α‐Oxocarboxylic Acids and Application in a One‐Pot Synthesis of Deuterated Aldehydes.
Authors: Niu Guang‐Hao , Huang Pei‐Ru , Chuang Gary Jing
Published: May 2016

A broad range of functionalized aryl α‐oxocarboxylic acids as well as hetaryl and alkyl substituted analogues serve as effective synthons for aldehydes which may be isolated in moderate to high yields.
ChemInform Abstract: Ruthenium‐Catalyzed Urea Synthesis Using Methanol as the C1 Source.
Authors: Kim Seung Hyo , Hong Soon Hyeok
Published: May 2016

The novel highly atom‐economical reaction between various benzylic or aliphatic amines, including diamines, and methanol allows for the preparation of symmetrical and unsymmetrical ureas.
ChemInform Abstract: A Mesoionic Bis(Py‐tzNHC) Palladium(II) Complex Catalyses “Green” Sonogashira Reaction Through an Unprecedented Mechanism.
Authors: Gazvoda Martin , Virant Miha , Pevec Andrej , Urankar Damijana , Bolje Aljosa , Kocevar Marijan , Kosmrlj Janez
Published: May 2016

A novel type of water soluble and thermally stable Pd‐NHC complex is used as an efficient catalyst for the copper‐, amine‐, phosphine‐, and additive‐free aerobic Sonogashira alkynylation of (hetero)aryl bromides in water.
ChemInform Abstract: Trifluorodiazoethane (CF3CHN2) in the Uncatalyzed Cyclopropanation of 3‐Arylmethylenebenzofuran‐2(3H)‐ones.
Authors: Zhu Chuan‐Le , Ma Jun‐An , Cahard Dominique
Published: May 2016

The simple method delivers the cyclopropanation products in high yields and with very high diastereoselectivities.
ChemInform Abstract: Domino Carbopalladation/C—H Functionalization Sequence: An Expedient Synthesis of Bis‐Heteroaryls Through Transient Alkyl/Vinyl‐Palladium Species Capture.
Authors: Sharma Upendra K. , Sharma Nandini , Kumar Yogesh , Singh Brajendra K. , Van der Eycken Erik V.
Published: May 2016

A series of 3‐ethylidene indolinones (III) is readily obtained by a Pd‐catalyzed reaction of alkynes (I) with oxadiazoles (II).
ChemInform Abstract: Cycloisomerization of Acetylenic Oximes and Hydrazones under Gold Catalysis: Synthesis and Cytotoxic Evaluation of Isoxazoles and Pyrazoles.
Authors: Jeyaveeran J. C. , Praveen Chandrasekar , Arun Y. , Prince A. A. M. , Perumal P. T.
Published: May 2016

Among the title isoxazoles (II) and pyrazoles (IV), compound (IIi) shows the highest cytotoxic potential towards the COLO320 cancer cell lines.
ChemInform Abstract: Copper‐Catalyzed Coupling of Oxime Acetates with Isothiocyanates: A Strategy for 2‐Aminothiazoles.
Authors: Tang Xiaodong , Zhu Zhongzhi , Qi Chaorong , Wu Wanqing , Jiang Huanfeng
Published: May 2016

The reaction tolerates aryl‐ and alkyl substituted oxime acetates and isothiocyanates, and offers access to 4‐substituted as well as 4,5‐disubstituted 2‐aminothiazoles.
ChemInform Abstract: Regioselective Dihydropyran Formation from 4‐Iodo‐2,6‐disubstituted Tetrahydropyran Derivatives Using In(OAc)3/LiI System as the Promoter.
Authors: Chalopin Thibaut , Jebali Khaoula , Gaulon‐Nourry Catherine , Denes Fabrice , Lebreton Jacques , Mathe‐Allainmat Monique
Published: May 2016

Starting from 2‐substituted homoallyl alcohols and various aldehydes a diastereomeric mixture of 2,6‐disubstituted 4‐iodotetrahydropyrans is prepared, and the products are further subjected to the regioselective elimination to form dihydropyran derivatives with an ether functionality in position 6.
ChemInform Abstract: Rhodium‐Catalyzed Tunable Oxidative Cyclization Toward the Selective Synthesis of α‐Pyrones and Furans.
Authors: Wu Jiaping , Wang Dongxu , Wan Yanjun , Ma Cheng
Published: May 2016

Rh‐Catalyzed cyclization of N‐tosylacrylamides [e.g. (I)] and diazo compounds [e.g. (II)] gives fully substituted pyrones [e.g. (III)] in the absence of an external oxidant, while furans [e.g. (VIII)] are obtained in the presence of AgOAc as an external oxidant.
ChemInform Abstract: A New Cascade Halosulfonylation of 1,7‐Enynes Toward 3,4‐Dihydroquinolin‐2(1H)‐ones via Sulfonyl Radical‐Triggered Addition/6‐exo‐dig Cyclization.
Authors: Zhu Yi‐Long , Jiang Bo , Hao Wen‐Juan , Wang Ai‐Fang , Qiu Jiang‐Kai , Wei Ping , Wang De‐Cai , Li Guigen , Tu Shu‐Jiang
Published: May 2016

The title synthesis follows a α,β‐conjugated addition/6‐oxo‐dig cyclization/radical coupling sequence.
ChemInform Abstract: FeCl3·6H2O‐Catalyzed Facile and Efficient Synthesis of Pyrano[4,3‐b]quinolines and Isochromenes.
Authors: Asthana Mrityunjaya , Singh Jay Bahadur , Singh Radhey M.
Published: May 2016

6‐Endo‐dig cyclization of alcoholic hydroxyl groups onto alkynes yields 1,3‐disubstituted 1H‐pyrano[4,3‐b]quinolines from ortho‐(arylethynyl)quinolinemethanol in good to excellent yields.
ChemInform Abstract: Synthesis and Insecticidal Evaluation of Tetrahydroimidazo[1,2‐a]pyridin‐5(1H)‐one Derivatives.
Authors: Liu Xuan‐Qi , Liu Ya‐Qin , Shao Xu‐Sheng , Xu Zhi‐Ping , Xu Xiao‐Yong , Li Zhong
Published: May 2016

A variety of the title compounds (III) (18 examples) are synthesized via an efficient aza‐ene reaction.
ChemInform Abstract: Three‐Component, One‐Pot Synthesis of Benzo[6,7]cyclohepta[1,2‐b]pyridine Derivatives under Catalyst Free Conditions and Evaluation of Their Antiinflammatory Activity.
Authors: Sajja Yasodakrishna , Vulupala Hanmanth Reddy , Bantu Rajashaker , Nagarapu Lingaiah , Vasamsetti Sathish Babu , Kotamraju Srigiridhar , Nanubolu Jagadeesh Babu
Published: May 2016

Six new pyridine derivatives (IIIa,b), (Va,b,c) and (IXb) show better anti‐inflammatory activities at micromolar concentration than the positive control piroxicam.
ChemInform Abstract: Rapid and Mild Synthesis of Quinazolinones and Chromeno[d]pyrimidinones Using Nanocrystalline Copper(I) Iodide under Solvent‐Free Conditions.
Authors: Abdolmohammadi Shahrzad , Karimpour Samira
Published: May 2016

The title compounds are efficiently obtained by one‐pot three‐component reaction of various aryl aldehydes, urea, and active methylene compounds under mild reaction conditions.
ChemInform Abstract: Catalytic Borylative Opening of Propargyl Cyclopropane, Epoxide, Aziridine, and Oxetane Substrates: Ligand Controlled Synthesis of Allenyl Boronates and Alkenyl Diboronates.
Authors: Zhao Jian , Szabo Kalman J.
Published: May 2016

The borylative ring opening reactions proceed with high regio‐ and stereoselectivity providing alkenyl diboronates or allenyl boronate products selectively depending on the choice of the phosphine ligand.
ChemInform Abstract: Silver‐Catalyzed Oxidative Cyclization of Propargylamide‐Substituted Indoles: Synthesis of Phosphorated Indoloazepinones Derivatives.
Authors: Hua Hui‐Liang , Zhang Bo‐Sheng , He Yu‐Tao , Qiu Yi‐Feng , Wu Xin‐Xing , Xu Peng‐Fei , Liang Yong‐Min
Published: May 2016

The simple and efficient protocol tolerates a broad range of substituents on the indole substrates as well as various diarylphosphine oxides, but no ethyl phenylphosphinate.
ChemInform Abstract: Metal‐Free Three‐Component Domino Approach to Phosphonylated Triazolines and Triazoles.
Authors: Ahamad Shakir , Kant Ruchir , Mohanan Kishor
Published: May 2016

The efficient domino reaction between aryl, hetaryl or alkyl aldehydes, including benzodicarbaldehydes, aliphatic amines and the Bestmann‐Ohira reagents provides 1,4,5‐trisubstituted 1,2,3‐triazolines.
ChemInform Abstract: Two New Flavanols from Glycosmis pentaphylla and Their Cytotoxic Activities.
Authors: Wang Jiangfeng , Zhao Bing , Zhang Feng , Zhang Qiongyu
Published: May 2016

The two new flavonols exhibit significant cytotoxic activities against HL‐60 and A549 cell lines.
ChemInform Abstract: Trichodermates A—F, New Cytotoxic Trichothecenes from the Plant Pathogenic Fungus Trichoderma sp.
Authors: Li Jiaying , Ren Jinwei , Bao Li , Jin Tao , Wang Wenzhao , Pei Yunfei , Liu Xingzhong , Li Erwei
Published: May 2016

Six new trichothecene polyunsaturated octadioic acid esters, trichodermates A—F [(I), (II), (III), (IV), (V), and (VI)], are isolated from the fermentation extract of trichoderma sp.
ChemInform Abstract: Muraymycin Nucleoside‐Peptide Antibiotics: Uridine‐Derived Natural Products as Lead Structures for the Development of Novel Antibacterial Agents
Authors: Wiegmann Daniel , Koppermann Stefan , Wirth Marius , Niro Giuliana , Leyerer Kristin , Ducho Christian
Published: May 2016

Review: [129 refs.
ChemInform Abstract: Chemistry of 4,4′‐(Arylmethylene)‐bis(3‐methyl‐1‐phenyl‐1H‐pyrazol‐5‐ol)s
Authors: Gouda Moustafa A.
Published: May 2016

Review: 59 refs.
ChemInform Abstract: Chemistry of Cigarette Smoking — A Review
Authors: Mitra Sankar P.
Published: May 2016

Review: 96 refs.
ChemInform Abstract: Synthesis, Reactions and Uses of Isocyanides in Organic Synthesis. An Update
Authors: Bode Moira L. , Gravestock David , Rousseau Amanda L.
Published: May 2016

Review: 453 refs.
ChemInform Abstract: Exploiting 3,3‐Difluoropropenes for the Synthesis of Monofluoroalkenes
Authors: Drouin Myriam , Hamel Jean‐Denys , Paquin Jean‐Francois
Published: May 2016

Review: [29 refs.
ChemInform Abstract: Recent Advances in Direct Catalytic Dehydrative Substitution of Alcohols
Authors: Dryzhakov Marian , Richmond Edward , Moran Joseph
Published: May 2016

Review: [180 refs.
ChemInform Abstract: Making a Long Journey Short: Alkyne Functionalization of Natural Product Scaffolds
Authors: Lehmann Johannes , Wright Megan H. , Sieber Stephan A.
Published: May 2016

Review: [68 refs.
ChemInform Abstract: Limits to the Applicability of the Rule of Equality to Unity of the Sum of Quantum Yields of Fluorescence and Transition to the Triplet State for Complex Organic Molecules in the Condensed Phase (A Review)
Authors: Ermolaev V. L. , Sveshnikova E. B.
Published: May 2016

Review: 104 refs.
ChemInform Abstract: Discovery of Non‐Peptide Small Molecular CXCR4 Antagonists as anti‐HIV Agents: Recent Advances and Future Opportunities
Authors: Zhang Heng , Kang Dongwei , Huang Boshi , Liu Na , Zhao Fabao , Zhan Peng , Liu Xinyong
Published: May 2016

Review: 69 refs.
ChemInform Abstract: An Integrated Overview on Pyrrolizines as Potential Antiinflammatory, Analgesic and Antipyretic Agents
Authors: Gouda Ahmed M. , Abdelazeem Ahmed H.
Published: May 2016

Review: 74 refs.
ChemInform Abstract: An Overview of Fuel Cells and Simulation Models: Review on Solid Oxide Fuel Cells
Authors: Canchaya Jose G. S. , Furtado Nelson C. , Taft Carlton A.
Published: May 2016

Review: 116 refs.
ChemInform Abstract: Principles of Precursor Design for Vapour Deposition Methods
Authors: Koponen Sara E. , Gordon Peter G. , Barry Sean T.
Published: May 2016

Review: 32 refs.
Characterization of Metal‐Organic Frameworks Using X‐ray Diffraction
Authors: Herrmann Michael , Kempa Paul Bernd , Fietzek Harald , Altenburg Thomas , Polyzoidis Angelos , Piscopo Calogero Giancarlo , Löbbecke Stefan
Published: May 2016

Metal‐organic frameworks (MOFs) are nanoporous materials with a very large inner surface. Selected MOFs with a high potential for industrial application are investigated and characterized using X‐ray diffraction. During this process, impurities and defective batches can be detected at an early stage and the manufacturing processes could be refined or corrected accordingly. In addition, important information on the real structures of the products is obtained. It is thus possible to achieve the target structure and to tailor particle properties to the application profile.
Refinement and revalidation of the demoralization scale: The DS‐II—external validity
Authors: Robinson Sophie , Kissane David W. , Brooker Joanne , Hempton Courtney , Michael Natasha , Fischer Jane , Franco Michael , Sulistio Merlina , Clarke David M. , Ozmen Mehmet , Burney Susan
Published: May 2016

BACKGROUND

The recently refined Demoralization Scale‐II (DS‐II) is a 16‐item, self‐report measure of demoralization. Its 2 factors—Meaning and Purpose and Distress and Coping Ability—demonstrate sound internal validity, including item fit, unidimensionality, internal consistency, and test‐retest reliability. The convergent and discriminant validity of the DS‐II with various measures is reported here.

METHODS

Patients who had cancer or other progressive diseases and were receiving palliative care (n = 211) completed a battery of questionnaires, including the DS‐II and measures of symptom burden, quality of life, depression, and attitudes toward the end of life. Spearman ρ correlations were determined to assess convergent validity. Mann‐Whitney U tests with calculated effect sizes were used to examine discriminant validity and establish the minimal clinically important difference (MCID). Cross‐tabulation frequencies with chi‐square analyses were used to examine discriminant validity with major depression.

RESULTS

The DS‐II demonstrated convergent validity with measures of psychological distress, quality of life, and attitudes toward the end of life. It also demonstrated discriminant validity, as the DS‐II differentiated patients who had different functional performance levels and high/low symptoms, with a difference of 2 points between groups on the DS‐II considered clinically meaningful. Furthermore, discriminant validity was demonstrated, as comorbidity with depression was not observed at moderate levels of demoralization.

CONCLUSIONS

The DS‐II has sound psychometric properties and is an appropriate measure of demoralization. Given its structural simplicity and brevity, it is likely to be a useful tool in meaning‐centered therapies. Cancer 2016;122:2260–7. © 2016 American Cancer Society.
Demoralization syndrome: New insights in psychosocial cancer care
Authors: Grassi Luigi , Nanni Maria Giulia
Published: May 2016

Demoralization is confirmed as a significant clinical dimension that needs to be part of the vision physicians should have when treating cancer patients. It is not a psychiatric disease but the expression of an unfolding, situational existence already involved in an irreducibly complex social world, in which cancer and its consequences as traumatic stressors impact the patient's experience and feelings, inducing a profound sense of emotional suffering.

See also pages 2251–9, 2260–7.
Diagnostic concordance of non–small cell lung carcinoma subtypes between biopsy and cytology specimens obtained during the same procedure
Authors: Ebrahimi Mojgan , Auger Manon , Jung Sungmi , Fraser Richard S.
Published: May 2016

BACKGROUND

The objectives of this study were: 1) to determine the diagnostic concordance of non–small cell lung carcinoma (NSCLC) subtypes in cytology and biopsy specimens taken during the same procedure and evaluate the causes of discordance; and 2) to determine the frequency of immunohistochemistry (IHC) use for subtyping NSCLC.

METHODS

Biopsy and cytology specimens that were obtained at the same procedure and diagnosed as NSCLC between January 2011 and December 2014 at the McGill University Health Center were identified (n = 226 pairs). The diagnostic concordance between the 2 methods was evaluated. The slides from discordant cases were reviewed, and final diagnoses were made based on IHC, resection specimens, or pathologist discussion.

RESULTS

Concordance in subtype diagnosis was perfect (adeno‐adeno or squamous‐squamous) in 66.2% of cases and was partial (adeno or squamous vs non–small cell) in 23%; discordance (adeno vs squamous) was observed in 7.8%. Although subtyping was not possible (ie, the final diagnosis was NSCLC, not otherwise specified) in 12.8% of biopsy specimens and 16.3% of cytology specimens, specific subtyping was not achieved in only 3% of cases when both modalities were considered. IHC was used in 47% of biopsy cases and 13% of cytology cases.

CONCLUSIONS

Subtyping of NSCLC can be achieved in most cases (97%) by considering findings in both biopsy and cytology specimens, and concordance in subtyping between cytology and biopsy specimens can be reached in a high percentage of cases (89.2%). Cancer Cytopathol 2016;124:737–43. © 2016 American Cancer Society.
Design and evaluation of a parallel neighbor algorithm for the disjunctively constrained knapsack problem
Authors: Quan Zhe , Wu Lei
Published: May 2016

We investigate the use of a parallel computing model for solving the disjunctively constrained knapsack problem. This parallel approach is based on a multi‐neighborhood search. In this approach, search threads asynchronously exchange information about the best solutions and use the information to guide the search. The performance of the proposed method was evaluated on the set of the standard benchmark instances. We show encouraging results and compare them to the state‐of‐the‐art solutions. Copyright © 2016 John Wiley & Sons, Ltd.
A new secure authentication scheme for cloud computing environment
Authors: Namasudra Suyel , Roy Pinki
Published: May 2016

Cloud computing is an emerging computing area that allows on‐demand, scalable, flexible, and low‐cost services to the users. In cloud computing, access control and security are two major problems. In this paper, a novel authentication scheme using Chebyshev chaotic maps has been presented. The proposed model satisfies many security factors, such as scalability of login, mutual authentication, freedom of password change, two‐factor security, and forward security. Two‐factor security is a method that requires two credentials for authentication, where the first factor may be something that users know and the second factor may be something that users have. Forward security assures the confidentiality of the user's session key, even if the private key of the server is compromised. In addition, the proposed scheme provides users with untraceability and anonymity, which means that any kind of adversary neither gets the identities of users or servers nor link several sessions with a user or server. The proposed model is secured under the computational Diffie–Hellman assumption of Chebyshev polynomials in the random oracle model. Moreover, security and performance analysis show that the proposed scheme can resist different security attacks in cloud computing environment and it is better than existing schemes. Copyright © 2016 John Wiley & Sons, Ltd.
Specific Anion Effects on the Kinetics of Iodination of Acetone
Authors: Lo Nostro Pierandrea , Mazzini Virginia , Ninham Barry W. , Ambrosi Moira , Dei Luigi , Baglioni Piero
Published: May 2016

Specific ion effects on the kinetics of iodination of acetone in an acidic medium are investigated by UV/Vis spectrophotometry as a function of nature of the acid and temperature. The results indicate that the order of the reaction with respect to acetone is practically unaffected by the composition of the acid while the value of the mixed constant k1K increases according to the sequence HBr<HCl<HClO4<HF<H2SO4<H3PO4. The results are discussed in terms of the hydration free energy and size of the anion and of the interaction between the cationic intermediate and the anion.
Quantum and Classical Molecular Dynamics of Ionic Liquid Electrolytes for Na/Li‐based Batteries: Molecular Origins of the Conductivity Behavior
Authors: Vicent‐Luna Jose Manuel , Ortiz‐Roldan Jose Manuel , Hamad Said , Tena‐Zaera Ramon , Calero Sofia , Anta Juan Antonio
Published: May 2016

Compositional effects on the charge‐transport properties of electrolytes for batteries based on room‐temperature ionic liquids (RTILs) are well‐known. However, further understanding is required about the molecular origins of these effects, in particular regarding the replacement of Li by Na. In this work, we investigate the use of RTILs in batteries, by means of both classical molecular dynamics (MD), which provides information about structure and molecular transport, and ab initio molecular dynamics (AIMD), which provides information about structure. The focus has been placed on the effect of adding either Na+ or Li+ to 1‐methyl‐1‐butyl‐pyrrolidinium [C4PYR]+ bis(trifluoromethanesulfonyl)imide [Tf2N]−. Radial distribution functions show excellent agreement between MD and AIMD, which ensures the validity of the force fields used in the MD. This is corroborated by the MD results for the density, the diffusion coefficients, and the total conductivity of the electrolytes, which reproduce remarkably well the experimental observations for all studied Na/Li concentrations. By extracting partial conductivities, it is demonstrated that the main contribution to the conductivity is that of [C4PYR]+ and [Tf2N]−. However, addition of Na+/Li+, although not significant on its own, produces a dramatic decrease in the partial conductivities of the RTIL ions. The origin of this indirect effect can be traced to the modification of the microscopic structure of the liquid as observed from the radial distribution functions, owing to the formation of [Na(Tf2N)n](n−1)− and [Li(Tf2N)n](n−1)− clusters at high concentrations. This formation hinders the motion of the large ions, hence reducing the total conductivity. We demonstrate that this clustering effect is common to both Li and Na, showing that both ions behave in a similar manner at a microscopic level in spite of their distinct ionic radii. This is an interesting finding for extending Li‐ion and Li‐air technologies to their potentially cheaper Na‐based counterparts.
A Bifunctional Metal–Organic Framework: Striking CO2‐Selective Sorption Features along with Guest‐Induced Tuning of Luminescence
Authors: Mukherjee Soumya , Desai Aamod V. , More Yogeshwar D. , Inamdar Arif I. , Ghosh Sujit K.
Published: May 2016

A phenanthroline‐functionalized CdII aminoterephthalate [Cd(NH2‐bdc)(phen)]n (NH2‐bdc=2‐aminobenzenedicarboxylic acid, phen=1,10‐phenanthroline) metal–organic framework (MOF) displays CO2‐selective adsorption properties and photoluminescence induced by phenolic guests. The inherently guest‐free, rigid amine‐rich framework exhibits substantial CO2‐selective adsorption at ambient temperatures (both at 273 and 298 K) over other flue gases like N2, CH4, O2, Ar and H2, with a high isosteric heat of adsorption at zero coverage (ΔHads≈34 KJmol−1). Moreover, the fluorescent phenanthroline guest introduced to the MOF results in an excellent photoluminescence signature, which can serve as a marker for tuning phenolic‐guest‐induced luminescence. This marks the first report of observing distinct fluorescence responses to differentially functionalized phenolic analytes, in the domain of coordination polymer materials.
A Method for Sectioning and Immunohistochemical Analysis of Stem Cell–Derived 3‐D Organoids
Authors: Wiley Luke A. , Beebe David C. , Mullins Robert F. , Stone Edwin M. , Tucker Budd A.
Published: May 2016

This unit describes a protocol for embedding, sectioning, and immunocytochemical analysis of pluripotent stem cell–derived 3‐D organoids. Specifically, we describe a method to embed iPSC‐derived retinal cups in low‐melt agarose, acquire thick sections using a vibratome tissue slicer, and perform immunohistochemical analysis. This method includes an approach for antibody labeling that minimizes the amount of antibody needed for individual experiments and that utilizes large‐volume washing to increase the signal‐to‐noise ratio, allowing for clean, high‐resolution imaging of developing cell types. The universal methods described can be employed regardless of the type of pluripotent stem cell used and 3‐D organoid generated. © 2016 by John Wiley & Sons, Inc.