bluuebunny/crossref_metadata_2025 huggingface dataset:
Current Issues in the Application of the Provisions of the Law of Ukraine `On the Legal Regime of Martial Law` and Their Impact on the Administrative-Legal Status of Citizens During the Period of Martial Law
Authors: Korentsov Oleksandr
Published: December 2024

Abstract.                                                                                                                          The relevance of the conducted study is determined by the lack of comprehensive scientific research regarding the protection of citizens' rights during the enforcement of martial law. The purpose of the article is to analyze the provisions of the Law of Ukraine "On the Legal Regime of Martial Law" in terms of their impact on the administrative and legal status of citizens under martial law. General scientific and special methods of scientific inquiry were employed, including formal-logical, dialectical, systemic analysis, and dogmatic methods. The author conducted a systematic analysis of the provisions of the Law `On the Legal Regime of Martial Law`, addressing issues of potential violations of human and civil rights and freedoms due to the application of certain provisions of this law and their compliance with the norms of the Constitution of Ukraine. Factors and conditions for the introduction of martial law, as specified in the definition of `martial law` (Article 1), were analyzed, leading to the conclusion that the definition provided in the law does not fully correspond to the essence of the legal regime of martial law. It permits the imposition of martial law under conditions that do not pose a threat to the life and health of citizens or to the independence of the state, resulting in unjustified restrictions on citizens rights and freedoms. Based on the study, a revised definition of `martial law` was proposed, incorporating substantial changes compared to the existing law. This revised definition excludes the possibility of unwarranted imposition of martial law and stipulates restrictions only on specific rights and freedoms during its enforcement. To ensure the protection of citizens rights and freedoms, it is proposed to introduce two distinct emergency legal regimes in Ukraine related to external threats (aggression): a `state of threat (attack) regime` and a more stringent `martial law regime`. For each regime, the powers of state authorities, appropriate legal measures, and provisions for transitioning from one regime to another in the event of armed aggression must be defined. It is concluded that the implementation of the norms of the Law `On the Legal Regime of Martial Law`particularly the measures under the martial law regime, must not violate fundamental human and civil rights and freedoms that cannot be restricted even under martial law conditions. If the application of these norms leads to violations of citizens`rights, such norms must be amended or excluded from the law`s text.
Resim ve Fotoğraf İlişkisinde Tasarım Öğesi Olarak Işık ve Renk
Authors: Yıldırım Nevzat , Nuhoğlu Mehmet
Published: December 2024

Resim ve Fotoğraf İlişkisinde Tasarım Öğesi Olarak Işık ve Renk

Light and Color as Design Elements in the Relationship Between Painting and Photography

Nevzat Yıldırım**, Dr. Mehmet Nuhoğlu***

Öz
Bu makalede ışığın hem fizik bilimi hem de sanat açısından tanımları araştırılmıştır. Işık ve renk kavramlarının resim ve fotoğraftaki kullanımı detaylı olarak incelenmiştir. Sanat tarihinde ve günümüzdeki örneklerle ışığın resim ve fotoğraf sanatıyla ilişkisi analiz edilmiştir. Eski döneminden günümüze sanatçılar, eserlerinde ışık ve renk kullanarak derin anlamlar katmışlardır. Bu araştırmada, ışık ve renk teorileri ile plastik sanatlar arasındaki etkileşimi son derece önemli olduğu görülmüştür. Işığın doğru ve estetik kullanımı, resim ve fotoğraf sanatlarında etkili kompozisyonları ortaya çıkarmaktadır. Araştırmada nitel araştırma yöntemleri kullanılarak ortaya çıkan temel bulgu, ışığın ve rengin sanatsal kompozisyonlarda estetik etkiyi artırdığıdır. Bu sayede ışığın iki boyutlu eserleri üç boyutlu hale getirme olasılığı örnekler ile vurgulanmıştır. Sonuç olarak ise resim ve fotoğraf ilişkisinden hareketle ışığın estetik ve sanatsal etkisini araştırılmıştır. Böylelikle fotoğraf ve resim sanatında ışığın estetik olarak kullanımı ve önemi üzerinde bir değerlendirme yapılmıştır.

Anahtar Kelimeler: Işık, Renk, Fotoğraf, Resim, Barok Dönemi.
Confabulações tecnopoéticas
Authors: Borges Bezerra Daniele
Published: December 2024

Neste artigo, interessa problematizar, a partir de uma perspectiva antropológica inspirada nos escritos de Donna Haraway, as relações entre tecnologia, IA, imaginário e imaginação, considerando a popularização e o consumo da IA na vida contemporânea, bem como, a circulação de narrativas do gênero ficção científica em produções audiovisuais nas quais a temática é abordada. Em termos metodológicos, além do recorte temático, a filmografia selecionada compreende um recorte temporal situado entre os séculos XX e XXI que parte de um cenário distópico ficcionalizado, observado nas primeiras produções sobre o tema e culmina com tecnologias contemporâneas que foram antecipadas por aquele olhar visionário. A proposta de um devir-com entre humanos e máquinas, sugere em um nível especulativo, que as imaginações humanas não são apenas estimuladas pelas potencialidades das IAs, mas podem também ser mediadas por elas e transformar-se em colaboração mútua.
Servindo a dois senhores? um panorama sobre servidores requisitados na despesa com pessoal da Justiça Eleitoral
Authors:   , Azevedo Jailton Fernandes de
Published: December 2024

No Brasil, leis específicas permitem que órgãos públicos requisitem servidores de outros órgãos
para atender suas demandas, o que pode causar uma dupla perda para os órgãos de origem, que
não podem contar com esses servidores e ainda precisam inicialmente arcar com sua
remuneração. O objetivo deste estudo é identificar o panorama das requisições de servidores
públicos no orçamento de despesa com pessoal e encargos sociais da Justiça Eleitoral (JE). Foi
realizado um levantamento nas páginas de transparências dos Tribunais Eleitorais do
quantitativo de servidores e empregados não integrantes do quadro próprio que foi comparado
com o montante de despesas liquidadas no elemento de despesa 96 (Ressarcimento de Pessoal
Requisitado) no exercício de 2022. Além desse comparativo, tentou se identificar a correlação
de Spearman entre a despesa executada e a quantidade de municípios, zonas eleitorais,
eleitorado e cargos efetivos providos das Unidades que compõem a JE. Foram identificadas
correlações negativas moderadas e fortes com o quantitativo de zonas eleitorais, de municípios,
de cargos efetivos providos e do eleitorado Tribunais Regionais Eleitorais. Também foi
calculado o custo mínimo de substituição desses servidores por cargos de provimento efetivo
da carreira, que representaria um incremento de aproximadamente 15% nas despesas com
pessoal e encargos sociais previstas no orçamento para 2023 da JE. Esses resultados contribuem
para uma melhor compreensão da dependência de servidores requisitados por parte da
instituição e podem auxiliar no planejamento orçamentário para os próximos exercícios
financeiros.
Educação e trabalho feminino: impactos sociais e econômicos da desigualdade de gênero
Authors:   , Ribeiro Danielle França
Published: December 2024

A desigualdade de gênero impacta no bem-estar das mulheres e de toda a sociedade, assim como também tem efeito sobre o desempenho econômico dos países. Por ser um fenômeno social complexo, é reforçada por variados eventos que ocorrem ao longo da vida das mulheres. Consistindo em um problema histórico e atual, deve ser objeto de reflexão a fim de diminuir as distâncias sociais e econômicas entre os homens e mulheres. Dessa forma, este estudo tem como objetivo discutir, a nível internacional e sob perspectiva de gênero, as relações entre educação das mulheres, trabalho feminino e economia dos países. Para isso, esta dissertação é formada por três artigos: i) o primeiro mede a relação entre o trabalho infantil feminino e a evasão na educação básica; ii) o segundo mensura o impacto da força de trabalho feminina no crescimento econômico; iii) o terceiro investiga a relação da educação sobre o nível de desemprego feminino. Trata-se de um estudo aplicado, descritivo e quantitativo. Foram utilizados dados secundários da base de pesquisa internacional Quality of Government Institute (QoG) e a análise ocorreu por meio de métodos estatísticos e econométricos. Como resultado, observou-se que o aumento de meninas no labor infantil é acompanhado por maior abandono escolar, principalmente em países com maiores índices de pobreza, também foram observados indícios de que o menor índice de trabalho infantil e a maior permanência escolar estão relacionados com políticas de transferência de renda e investimento educacional, inclusive com programas de alimentação escolar. Além disso, foi constatado que os determinantes do crescimento econômico PIB per capita PPP e crescimento do PIB per capita são influenciados pela participação das mulheres no mercado de trabalho, contudo é necessário atentar para a minimização dos preconceitos vivenciados por elas nesse espaço. Por fim, analisou-se que o investimento em educação realizado pelas mulheres não acarreta, necessariamente, na maior facilidade de ingresso e permanência no mercado de trabalho.
KIF4A on TGF-Β1/Smad3 Pathway: A Preliminary Investigation on the Proliferation and Immune Response in In-Vitro Cultured Breast Cancer Cells
Authors: Zhang Hu , Jing Meng , Du Xinna
Published: December 2024

Aim:

This study aims to explore the relevant biomarkers in breast cancer (BC).

Background:

Kinesin family member 4A (KIF4A) is a member of the Kinesin 4 subfamily of
kinesin-related proteins, which has already been investigated in diverse types of tumors.

Objective:

Our current study aims to investigate the involvement of KIF4A in BC.

Methods:

KIF4A expression level was firstly predicted based on the data from the Cancer Genome
Atlas (TCGA) and then assessed in BC cells. Subsequently, after silencing KIF4A, its effects
on BC cell proliferation and metastasis, as well as on immune-related cytokines, were assessed
by cell counting kit-8 (CCK-8), 5-Ethynyl-2'-deoxyuridine (EdU) staining and quantitative
Polymerase Chain Reaction (qPCR). Next, western blotting assays were used to detect the
expression and phosphorylation levels of transforming growth factor-beta 1 (TGF-β1) and small
mothers against decapentaplegic 3 (Smad3) in BC cells after KIF4A silencing and the role of the
pathway was verified by Smad3 inhibitor (SIS3).

Results:

KLF4A was highly expressed in BC, and silencing of KIF4A repressed the proliferation
and metastasis potential of in-vitro cultured BC cells, concurrent with the reduction of
CDH2, VIM, and SNAIL levels, yet the increase in the expression of CDH1. In the meantime,
KIF4A knockdown diminished the levels of IL4, IL10, and TGFB while promoting those of
IL1B and IL6 in BC cells. Further, enhanced phosphorylation of Smad3 was observed in BC
cells, and the intervention of SIS3 restrained the proliferation and metastasis potential of BC
cells and reduced the expression levels of CDH2, VIM, and Snail whilst promoting that of
CDH1. Additionally, SIS3 intervention increased IL1B and IL6 levels and decreased IL4, IL10
and TGFB levels in BC cells.

Conclusion:

This study preliminarily explored the involvement of KIF4A and TGF-β1/Smad3
together in BC, which may provide another insight into the management of BC in clinical practice.
Tacrolimus, Cytochrome P450, Interactions with Food Variables in Organ Transplant Recipients; A Current and Comprehensive Review
Authors: Tolou-Ghamari Zahra
Published: December 2024

The well-established calcineurin inhibitor, tacrolimus, as an immunosuppressive agent, is widely
prescribed after organ transplantation. Cytochrome P450 (CYP 450) isoforms are responsible for the
metabolism of many features associated with food parameters like phytochemicals, juices, and fruits. This review
article summarizes the findings of previous studies to help predict the efficacy or side effects of tacrolimus
in the presence of food variables. From the commencement of databases associated with the topic of interest
to 26 October 2024, all relevant articles were searched through PubMed, Scopus, and Web of Science. The
suggested therapeutic range for tacrolimus trough concentration (C0 ) was reported as 5-15 ng/ml blood.
Tacrolimus interaction with food variables could significantly change C0 after organ transplantation. For example,
grapefruit juice could increase tacrolimus C0 due to CYP enzyme inhibition. Toxicity such as nephrotoxicity
could result from turmeric and other herbal or food products. By inhibiting tacrolimus-metabolizing enzymes
and transporters, a high intake of vegetables could increase the risk of adverse effects. Secondary
metabolites of vegetables could lead to toxicity in patients with tacrolimus. Furthermore, grapefruit juice, citrus
fruits, turmeric, and pomegranate juice could change clinical pharmacokinetics parameters such as Tmax,
Cmax, AUC, and C0 of tacrolimus after organ transplantation. Bioavailability of tacrolimus might be decreased
by induction of the CYP450 system and P-gp efflux pump due to cranberry, rooibos tea, and boldo. Increased
inhibitory effect on CYP450 system and/or P-gp efflux pump by grapefruit juice, schisandra, berberine, turmeric,
pomegranate juice, pomelo, and ginger could increase bioavailability of tacrolimus. A vigilant immunosuppressive
strategy accompanied by scheduled therapeutic drug monitoring is recommended before and after transplant
surgery.
CT Perfusion Metrics as Indicators of Intracranial Atherosclerotic
Stenosis in Acute Ischemic Stroke: A Clinical Analysis
Authors: Liu Yunpeng , Huang Jumei , Jia Jianwen , Zuo Yingting , Wang Yang , Liu He
Published: December 2024

Background:

Intracranial Atherosclerotic Stenosis (ICAS) is a prevalent etiology of
acute ischemic stroke (AIS), leading to significant morbidity and mortality. The accurate diagnosis
and treatment of ICAS-induced AIS are critical to improving outcomes. This study assesses
the application of Computed Tomography Perfusion (CTP) in predicting ICAS in AIS patients
and its potential impact on patient management.

Methods:

A retrospective analysis was conducted on 224 AIS patients who underwent endovascular
therapy (EVT) at one single Chinese Stroke Center between April 2022 and December
2023. Clinical and radiological data were collected, including patients’ demographics, CTP parameters,
and 90-day modified Rankin Scale (mRS) scores. Logistic regression and receiver operating
characteristic (ROC) curves evaluated the predictive power of CTP parameters for ICAS.

Results:

CTP analysis revealed significant differences in perfusion parameters between ICASinduced
AIS and other etiologies. ICAS patients had a smaller ischemic volume on admission
and higher mismatch ratios [Time to Maximum, Tmax＞6s: Other Causes: 132.4 [70.5, 183.3]
mL, ICAS: 96.3 [79.8, 107.3] mL, p =0.0064; relative cerebral blood flow, rCBF＜30%: Other
Causes: 2.4 [0.0, 10.8] mL, ICAS: 0.6 [0.0, 7.0] mL, p =0.0145; mismatch ratio: 7.4 [2.5, 15.0],
ICAS: 11.0 [4.6, 17.8], p =0.0285], indicating more salvageable brain tissue. The 90-day mRS
showed better functional outcomes in the ICAS group, with a higher likelihood of minimal to no
disability [mRS 90 equals 0-1: ICAS: 53.0% vs. Other Causes: 36.3%, p =0.0122]. The predictive
model for ICAS, combining clinical manifestations and CTP parameters, yielded an area
under the curve (AUC) of 0.7779, demonstrating good diagnostic performance.

Conclusion:

CTP is a valuable diagnostic tool for ICAS-induced AIS, offering the potential for
early identification and informing the decision for endovascular treatment. The positive correlation
between CTP findings and patient outcomes supports its utility in clinical practice.
Etiologies and Risk Factors by Sex and Age in Young Adult Patients with
Ischemic Stroke
Authors: Huang Linrui , Wang Yanhua , Wang Yanan , Wu Simiao
Published: December 2024

Aim:

The aim of this study was to explore etiologies and risk factors by age and sex
in young adult patients with ischemic stroke.

Methods:

We recruited patients with ischemic stroke aged between 18 and 49 years. We assessed
pathological etiologies by the Trial of Org 10,172 in Acute Stroke Treatment (TOAST)
classification and risk factors by the International Pediatric Stroke Study (IPSS) classification.
We explored the distribution of etiologies and risk factors by age and sex and investigated baseline
features associated with functional outcomes at 3 months.

Results:

Of 8521 stroke patients consecutively admitted, 1017 patients (11.9%) aged between
18-49 years, of whom large artery atherosclerosis was the most common etiology (n=375,
36.9%), followed by other determined cause (n=194, 19.1%) and undetermined cause (n=184,
18.1%). Compared to male patients, female patients had more cardioembolism (16.34% vs
8.42%) and less small artery occlusion (8.56% vs 17.76%). As age increased, the proportions of
large artery atherosclerosis (P <0.001) and small artery occlusion (P <0.001) increased, and the
proportion of other determined causes decreased (P <0.001). Of 184 patients with undetermined
causes, 173 (94.0%) had at least one IPSS risk factor. A higher serum level of D-dimer at baseline
was associated with an increased risk of unfavorable outcome (OR 1.118, 95% CI 1.052-
1.189), adjusting for the effect of age and stroke severity.

Conclusion:

Approximately one-fifth of young patients with ischemic stroke had undetermined
etiology, for whom the IPSS classification helps to explore risk factors. A higher level of Ddimer
was associated with a higher risk of unfavorable outcomes at 3 months.
Unlocking Therapeutic Potential: Molecular Docking Insights into Aurora
Kinase A Inhibitors Patented and Published from 2011-2020 for Innovative
Anticancer Drug Design
Authors: Rani Ketki , Mazumder Avijit , Gupta Manish K. , Arora Tripti
Published: December 2024

Background:

Enzymes belonging to the kinase family have been extensively implicated
in cancer. Aurora A (AURKA) is crucial in regulating the cell cycle. AURKA's significant
role in the formation of abnormal mitotic spindles and the failure of cytokinesis positions it as a
promising target for anticancer treatments. Notably, AURKA is observed to be overexpressed in
various cancer types, making its inhibition a compelling strategy for the development of anticancer
agents.

Objective:

In this study, we set out to investigate a novel de novo design strategy aimed at developing
and optimizing potent inhibitors for Aurora Kinase A. Given Aurora Kinase A's critical
role in cell cycle regulation and its overexpression in various cancers, it presents a promising
target for therapeutic intervention. Our goal was to create a new library of compounds, building
on existing inhibitors known for their selectivity and potency against Aurora Kinase A. By making
strategic modifications to these lead molecules, we aimed to improve their binding affinity
and inhibitory effectiveness. This research was focused on identifying and refining compounds
with enhanced drug-like properties and robust inhibitory potential, contributing to the advancement
of effective anticancer therapies.

Methods:

A compound library based on known inhibitors having Aurora Kinase A selectivity
and IC50 value in the nanomolar range was designed by modification in the lead molecules identified
by analyzing the binding mode of the molecules in the catalytic site of the enzyme. A molecular
docking study was performed in GOLD 2020. Drug-likeness ADME parameters (molecular
weight, H-bond acceptors, H-bond donors, LogP, and the number of rotatable bonds) of
designed molecules were calculated using SwissADME, pkCSM, and ProToxII web servers.

Results:

The docking study, utilizing GOLD 2020 software on Aurora Kinase A (PDB: 3W2C),
successfully identified inhibitors that hindered the enzyme's activity by occupying its catalytic
site. This inhibition mechanism, consistent across all cases, involves crucial interactions with
residues such as Ala213, Asp274, and Phe144. A detailed analysis of the compounds guided the
design of new analogs, aiming to enhance the lead compound's affinity for the receptor. Subsequent
derivatization of M1 and M15 resulted in molecules (M1_46, M1_49, M1_50, M15_21,
M15_14, and M15_43) showing a notable 10-15% increase in the Chemscore fitness scoring
function compared to their parent molecules. This improvement correlated with a rise in the
number of hydrogen bond interactions in the complexes, guiding further development.

Conclusion:

This computational assessment lays a foundation for further in-vitro and in-vivo
studies in drug development, suggesting these derivatives as promising candidates for cancer
treatment.
Simulation and Optimization of Start-up Process of High-speed Gas-liquid Two-phase Pump
Authors: Hu You Cai , Wang Zi Cheng , Wang Yan Wei
Published: December 2024

Background:

Centrifugal pump is widely used in industrial production as a key
fluid conveying equipment. The transient characteristics during its start-up process may
lead to vibration, noise and efficiency loss. Therefore, it is very important to optimize the
start-up process.

Objective:

Optimize the structural parameters of the centrifugal pump, with the initial
pulse values of both the head and efficiency as the optimization objectives, to enhance its
transient performance.

Methods:

The centrifugal pump was numerically simulated by computational fluid dynamics
method. In the optimization process, the BP neural network is established, and the genetic
algorithm is used to optimize the parameters, which improves the efficiency and accuracy
of parameter tuning.

Results:

The optimized head pulse value is reduced by 4.39 m, and the efficiency pulse
value is reduced by 5.65 %. Make the start-up process of centrifugal pump more stable.

Conclusion:

Among the parameters that affect the stability of the centrifugal pump start-up
process, it can be obtained that the three factors of impeller outlet width, blade outlet angle
and blade wrap angle have the greatest influence on the fluctuating head and efficiency of
the centrifugal pump.

other:

none
Research Progress on Forming Porous Structures based on Selective Laser Melting Technology
Authors: Gao Bingwei , Qin Mingjing , Shi Jingyao , Peng Liqing , Sun Zhixin
Published: December 2024

Background:

Based on the development of selective laser melting technology,
the machining of porous structures has become more delicate than conventional
machining methods and has great advantages in manufacturing in many fields.

Objective:

Types, properties, and design methods of porous structures are described,
along with the application areas of porous structures. The influence of SLM process
parameters on the molding of porous structures is also described.

Methods:

Journals on porous structures are cited and used to demonstrate the excellent
properties, application areas, and molding processes of porous structures.

Results:

Porous structures formed based on selective laser melting have excellent
properties and are used in a wide range of applications, such as medical phytomers
and aerospace.

Conclusion:

With the combination of selective laser melting technology and porous
structure design methods, porous structures are better developed and applied to many
fields.
Drug-Device Combinations in Dermatology: Integrating Pharmaceuticals with Advanced Cosmetic Technologies
Authors: Choudhary Anushka , Chauhan Shikha Baghel , Swami Rajan , Singh Indu
Published: December 2024

Background:

A paradigm shift is brought about by the combination of medicines with
cutting-edge medical technology, which improves patient outcomes, effectiveness, and accuracy.
The review dives into applications such as anti-aging therapy, nanotechnology, and acne treatment
while also examining obstacles, traditional procedures, and current breakthroughs. It highlights
the difficulties with patient adherence, safety, and regulatory barriers while projecting a
future where genetics, biosensors, and artificial intelligence will power tailored therapies. Emphasis
is placed on the potential for global dermatological health, imagining a time when drugdevice
combos would alter skincare globally.

Objectives:

This study aims to provide a comprehensive overview of the current landscape of
drug-device combinations in dermatology and advancement in drug-device combinations for dermatological
therapy.

Methods:

A literature search was performed on PubMed and Google Scholar using the following
key terms” Dermatology,” “Cosmetic technologies,” “Dermatopharmacology,” “Beauty Perception,”
and “Skincare.”

Result:

The assessment of the safety and effectiveness profiles of various drug-device combinations,
considering long-term effects, adverse events, patient satisfaction, and clinical results. This
includes an examination of the fundamental processes by which pharmaceuticals and cuttingedge
cosmetic technologies work together to produce therapeutic outcomes like improved drug
delivery, targeted therapy, and synergistic effects.

Conclusion:

In conclusion, drug-device combinations offer a viable way to improve therapeutic
outcomes and elevate patient care in dermatology by fusing pharmaceuticals with cutting-edge
cosmetic technology. Our analysis focuses on the wide range of combinations that are currently
available, as well as their effectiveness, safety profiles, and underlying mechanisms of action.
Even though there has been a lot of development, issues, including patient variability, technical
constraints, and regulatory barriers, still exist.
Where Are the Lactation Consultants: Mapping Their Impact on U.S. Breastfeeding Outcomes (Preprint)
Authors: Dockins James F , Pahl Heather D , Lingerfelt David J
Published: December 2024

BACKGROUND

This research project examines the relationship between the population density of International Board-Certified Lactation Consultants (lactation consultants) and breastfeeding outcomes in the United States.

OBJECTIVE

The study focuses on three key breastfeeding indicators: initiation, exclusive breastfeeding at three months, and exclusive breastfeeding at six months.

METHODS

Data was analyzed using simple and multiple linear regression analyses.

RESULTS

The findings suggest that lactation consultant density is positively correlated with breastfeeding outcomes. The correlation coefficients ranged from small to moderate, with lactation consultant density positively associated with increased rates of breastfeeding initiation, exclusive breastfeeding at three months, and exclusive breastfeeding at six months. This research contributes to the understanding of the role of lactation consultants in improving breastfeeding outcomes in the United States, highlighting the need for further research and initiatives to support the expansion of lactation consultant care.

CONCLUSIONS

The research underscores the value of lactation consultants in promoting positive breastfeeding outcomes, even when controlling for potential confounding factors. While there is wide variation in lactation consultant density across states, the study suggests that increasing access to lactation consultants could have a positive impact on breastfeeding success. Limitations include the availability and granularity of data, as well as the complexity of sociocultural influences on breastfeeding outcomes that may not be fully captured through quantitative analysis.
The Role of Toko Tani Indonesia (TTI) to Supply Chain and The Establishment of Rice Prices in Sragen District
Authors: Putri Hilda Anugrah , Irianto Heru , Antriyandarti Ernoiz
Published: December 2024

This research examines the role of Toko Tani Indonesia (TTI) in the rice supply chain and price determination in Sragen Regency, Central Java, Indonesia. Using a descriptive analysis approach, the study focused on Sragen, a major rice production center. The samples for this investigation were selected purposively from datasets provided by eleven Community Food Business Institutions and Indonesian Farmer’s Stores that have been recorded in the Office of Agriculture and Food Security of Sragen Regency. The Food Supply Chain Networking (FSCN) model and rice price formation were analyzed qualitatively, while supply chain performance and value-added (VA) were assessed quantitatively. Results revealed a significant reduction in the rice supply chain stages from 6–7 to just 3, improving efficiency. Margins for partner farmers and TTI were calculated at IDR 1,600 per kilogram (51.13% of total margin share) and IDR 300 per kilogram, respectively. Inventory turnover was 12 times annually, with inventory days of supply for farmer groups at 30 days and a cash-to-cash cycle of 37 days. VA analysis showed farmers contributed 72% of total value (IDR 376,216,168), LUPM 26% (IDR 136,678,955), and TTI 2% (IDR 8,090,000). TTI supports farmers by purchasing grains at fair prices, ensuring effective marketing, maintaining rice availability, and stabilizing prices, thus playing a critical role in the community's food security efforts.
Research on Disturbance Suppression Based Motion Axis Control of Machine Tools
Authors: Liu Sanqiu
Published: December 2024

For the high-precision tracking performance of machine tool motion axis control, this paper establishes a system mathematical model considering the elastic deformation of ball screws, and then designs a sliding mode controller to suppress the influence of uncertainty on control performance. Next, an extended state observer was designed to observe the system state and disturbances, and feed them back to the sliding mode controller for position control. Finally, the correctness of the designed sliding mode control and extended state observer was demonstrated through MATLAB simulation analysis.
Theoretical Acceptance and Practical Exploration of Marxism in the Work-Study Group in France
Authors: Li Ziqi
Published: December 2024

Since 1919, on the eve of the birth of the Communist Party of China (CPC), a group of aspiring young people travelled across the ocean to France to study and work, and to explore ways to save the country and make it strong. During their stay in France, they worked hard and studied thriftily, and at the same time penetrated into the French society, understood the workers' movement and came into contact with Marxism. They were the first group to turn their attention to Marxism, study and accept it, and spread it to China. They promoted the spread of Marxism in China and expanded the path of spreading it, which provided the theoretical basis for the establishment of the CPC; they actively carried out practical explorations, which influenced the establishment of the early organisations of the CPC, and at the same time, they set up CPC the European Branch of the CPC and the Chinese Socialist Youth League, which solidly formed the organisational basis of the CPC; they cultivated a large number of excellent Chinese Communists such as Cai Hesen and Zhou Enlai and enriched the early leadership force of the Party, laying the foundation for the Party's establishment and development. All of the above made indelible contributions to the origin and development of the CPC. However, their acceptance and exploration of Marxism also had historical limitations due to the limitations of social and historical conditions and the lack of their own understanding. At present, our country is in the critical period of realising the great rejuvenation of the Chinese nation, and the study of Party history is of great and far-reaching significance for summing up the historical experience, understanding the laws of history, grasping the initiative of history, passing on the red genes, bearing in mind the mission of the original heart and adhering to the correct direction.
Solid State Wave Gyroscope Parameter Assessment at Various Production Stages
Authors: Trutnev G. A. , Spiridonov F. I. , Mingazov R. I.
Published: December 2024

The paper considers a solid-state wave gyroscope and describes the principles of its operation. Key stages of production together with parameters of solid-state wave gyroscope, characterizing quality, are studied and analyzed. The problem of automated quality control system development is raised. The set of gyroscope parameters, physical parameters of resonator oscillation modes, is chosen. The proposed set of parameters gives full description of device quality and can be analyzed at any of key production stages. So as to develop the evaluation method for solid-state wave gyroscope parameters a solid-state wave gyroscope mathematical model, as a free oscillation partial oscillator, that relates the phase variable dynamics with physical parameters, is analyzed. The resonator intrinsic wave drift rate being the principal quality parameter of gyroscope is studied. The relation between the drift rate and solid-state wave gyroscope physical parameters is considered. The measuring diagram for the suggested parameter set is developed on the basis of considered mathematical models, the technique is proposed, and software solutions for suggested approach implementation is developed. Structure diagram and state chart for the proposed solid-state wave gyroscope measurement parameters are described. The proposed diagram consists of two components: measurement and computational ones. The performance features of each component are described. Various operation modes of solid-state wave gyroscope parameter evaluation system are considered: free oscillation mode, wave pattern rotation, operation mode, and transition processes. The problem of applicability and efficiency of the proposed solutions is studied. The example of the developed system application is given. The results of obtaining the operating mode drift rate direct evaluation and drift rate evaluation obtained according to mathematical model and evaluated solid-state wave gyroscope physical parameter are analyzed. Possible ways of solid-state wave gyroscope parameter evaluation method improvement are considered.
Control of Production Process Material Flows
Authors: Aizenshtat D. A. , Dokuchaev D. E. , Smirnov S. V.
Published: December 2024

The article considers mathematical models and algorithms for material flowcontrolin production. Production of bakery goods and downhole equipment are taken as areas of application. Limitations, associated with the specifics of production entities in each area are described, in particular, effective utilization of enterprise warehouse reserves to ensure production process alterations to adapt the plan to market variability in terms of the supply cost and price levels of the manufactured products. It is proposed to automate the enterpriseactivities related to delivery orderplacement for interaction with suppliers, taking into account various factor alterations, as well as a reporting module applicationfor situation assessment and making out reports, simplifying the work of enterprise and departmentmanagers related to decision-making. The operational control of material flows during production is considered. The concept of production material flowcontrol is introduced as a comparison of raw materialamount intended for the productmanufacturing, the amount of raw materialstandard costs in productproduction within the framework of the main production plan and the available corresponding raw material reserves. The problem of material resource control is solved. The conclusions obtained during the study will serve as the basis for the information system development, that includes the compiling a list of materials, accounting of finished product in the warehouse, as well as accounting for ingredients unutilized during the production and remaining in warehouses, creation of a consumed material register and accounting of documents, the system will allow entering data in real time mode.
Software Development for Automated Design of Principal Women Wear Patterns
Authors: Bakaeva O. A. , Shurgina E. D.
Published: December 2024

In this article the review of IT-tools for pattern design is carried out. The problems and disadvantages of the used software are identified and the development of a software for the automated principal pattern design of women's clothing “PIONY”, which has a number of advantages, is described. These include free functionality, three modes of operation (“Guest”, “Shaper”, “Shaper+”), personal account, the ability to save the pattern in the required format and scale. Also, this system allows for an unauthorized user to work in the system, providing him with incomplete functionality ofdesigning a pattern of one product on a standard size in accordance withRussian National Standard GOST. The main advantage of the software is the ability todesign patterns of five items (top, robe, pants, shorts and skirt) according to individual user’smeasurements, taking into account additional parameters (additions, and type of silhouette), and print it in real scale. The software structure is presented in the form of a UML-diagram. It reflects the activities of the administrator and the user. The program part of the functionality is developed using the programming languages JavaScript, PHP, built-in GD Library, which allows creation drawings using graphical primitives and work with image files. Library functions are used to build geometric objects, drawing simple shapes such as lines, circles, which are the pattern elements. A set of hypertext markup HTML and CSS stylingwas usedfor the interface part. The proposed software will allow people who do not have professional knowledge in the field of sewing to design patterns automatically according to individual measurements by entering data and pressing a few buttons.
Method of Two-Parameter Signal Processing from Thickness Gauge Eddy-Current Measuring Transducers of Non-Conductive Coatings on Non-Magnetic Metal Bases
Authors: Syasko M.V.
Published: December 2024

The well-known existing amplitude-sensitive eddy-current method for measuring the thickness of a non-conductive coating on a non-magnetic base metal does not meet modern requirements for measurement accuracy, in particular, when measurement result is highly influenced by a change in the specific electrical conductivity of the base metal. The purpose of this study is to increase the reliability of thicknessmeasurements of non-conductive coatings on non-magnetic base metals by taking into account (suppressing) the influence of the base metalspecific electrical conductivity. To achieve this goal, a three-winding transformer compensated eddy-current probe was used. Its output signal is represented in a complex form by real and imaginary components on a complex plane, which makes it possible to implement the amplitude-phase-sensitive method of eddy-current non-destructive testing. The developed method of two-parameter signal processing based on the algorithm for determining point belonging to a polygon is described. The implementation of the latter is realized by a two-dimensional calibration of the thickness gauge with several reference bases with different specific electrical conductivity, displayed on the complex plane in the form of a fan-shaped grid. The specified algorithm determines which section of this grid the eddy-current probe signal belongs to, while the order number of the determined section reflects both the coating thickness and the specific electrical conductivity of the base metal as independent quantities. The method of selecting the number of calibration points is described, based on choosing the optimal interval between them according to the criteria of probability ofmeasurement result distribution. The non-conductive coating thickness simulating system has been developed, connecting by two-way communication with a graduated thickness gauge and implementing its automatic calibration. The test results of the applied method for measuring the thickness of a non-conductive coating on a non-magnetic base metal are presented, that showed a decrease in the deviation of the coating thickness measurementresults under the influence of the base metal specific electrical conductivity by two orders of magnitude.
Robotized Bottling Line Efficiency Evaluation Based on Simulation Modeling and Operational Performance Metrics
Authors: Kvas E.S. , Kuzmenko V.P.
Published: December 2024

This study presents a simulation model for assessing the production stability of a robotized bottling line for carbonated beverages into 0.5-liter glass bottles. The goal of the research was to develop a simulation model to analyze factors affecting line operation stability and production balance. The model considers the stochastic characteristics of processing time at each station, the probability of equipment failures and repairs, and the dynamics of buffer filling, enabling the assessment and maintenance of line operation stability. During the simulation, hypotheses were explored regarding the impact of buffer capacity on the overall equipment effectiveness (OEE) and resource planning processes based on failure frequency data. Simulation results demonstrated that there is an optimal buffer capacity at which line efficiency is maximum. The developed simulation model provides an effective tool for analyzing and optimizing the buffer capacity management process within a bottling line. The scientific novelty of the study lies in the integration of stochastic methods and production process dynamics with the probability of quality indicator variation at each stage. The practical significance of the work lies in the model’s direct applicability for optimizing production lines and enhancing their market competitiveness.
Elements of Educational Technology 4.0 on the Example of Augmented Reality Using an Avatar of an Anthropomorphic Dental Robot Simulator
Authors: Baidarov A.A. , Kokoulin R.A. , Storozhev S.A. , Yuzhakov A.A. , Arutyunov S.D. , Astashina N.B.
Published: December 2024

This paper presents an innovative solution for dental education within the framework of Industry 4.0: an anthropomorphic dental simulator combining the advantages of robotics, virtual reality (VR), and augmented reality (AR). The integration of a six-axis KUKA robotic arm with the Unity virtual environment provides a high degree of realism in simulating dental procedures. The use of neural networks allows for objective assessment of student performance by analyzing video streams from cameras inside the simulator's oral cavity. The research aims to build educational environment elements based on Industry 4.0 technology, utilizing gamification and avatars. The novelty of this research lies in the unique combination of an industrial robot, VR/AR technologies, and artificial intelligence to create a personalized and interactive learning environment. The development methodology involved creating a virtual jaw model, programming the robot for precise movements, and training neural networks on a large dataset. Results demonstrated that the developed simulator significantly improves learning efficiency, reduces student adaptation time, and allows for objective assessment of their skills. Future development includes integration with other medical simulators, the creation of adaptive learning programs, and the application of artificial intelligence for deeper analysis of learning data. The examples presented in this paper confirm the effectiveness of the proposed approach and open new perspectives in the development of innovative training simulators for dentistry. The anthropomorphic dental simulator presented allows for the application of augmented reality in remote dental education and the simulation of various diseases, significantly improving the practical training of both instructors and students for working with patients.
THE MODEL OF CHOOSING A CRM SYSTEM IN THE MANAGEMENT OF BUSINESS ROCESSES OF SMALL BUSINESSES
Authors: Zlobina E. U. , Matveeva I. V.
Published: December 2024

The article presents a model for choosing a CRM system for small and medium-sized enterprises (SMEs), which allows for effective business processes of interaction with clients. The authors came to the conclusion that in modern conditions, digitalization of SME activities is becoming one of the pressing issues.Active digitalization of business accelerates the process of transition of the economy to digital. The digital economy is based on information and communication technologies (ICT). Information technologies in the modern economy are used for the purpose of fast, high-quality and effective computer processing of information resources, their transmission over any distance in the shortest possible time. The authors argue that government support for business digitalization cannot and should not be the only stimulating factor for SMEs. In addition to external conditions, there are also internal motivating factors - these are the capabilities of the business environment. The authors of the article substantiate the idea that CRM systems allow optimizing the process of financial and economic interaction between a company and a buyer. Using the hierarchy analysis method, the key parameters for choosing a CRM system were determined. The final indicator of the CRM system selection allows choosing the optimal CRM system for the enterprise from alternative ones. The indicator is calculated based on the second-level indicators: the functionality of the CRM system, the program interface, the tariff scale.Each of these indicators is disclosed through the indicators of the 3rd level. The weights of the indicators of all levels were determined by experts through a pairwise comparison of the elements of each level on a nine-point scale. The criteria and their weight values proposed by the authors will allow SME sector entities to choose the optimal program depending on the requests and capabilities of the enterprise.
COST EVALUATION OF EXISTING PRODUCTION
Authors: Lihachev V. N.
Published: December 2024

The issues of cost evaluation of existing production have been in the focal point while in transit to market economy. The article analyses the notion of “the cost of existing enterprise” (CEE) defined in scientific literature and official documentation such research publications, thesauruses, textbooks, documents issued by RF Ministry of Finance. The publications of those engaged in accounting are also in the focal point of this submission. The analysis made is intended to help to remedy the disadvantages of existing cost evaluation methodology. The author provides comparative analysis of interpretation of this notion, adjust its contents and justify the necessity of counting such cost components as goodwill in cost evaluation of an enterprise. The methodology of the profitable approach to estimating the cost of production based on discounted cash flows in an unlimited billing period is analyzed, as well as the presented direct method for calculating the CEE by the amount of complex non-current and current capital used for the reporting period. The article introduces the methodology of CEE calculations based on the total value of capital (current assets and fixed assets). The formula of CEE calculations with goodwill counted is viewed as seller’s extra earnings transformed in a particular part of future balance costs of a buyer company, which is increasing its capital costs and reducing its production efficiency to some average industry standard. The article is aimed at managers, entrepreneurs, investors, professional appraisers, employees of investment companies and banks, teachers, students and postgraduate students.