bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring New Antioxidant and Mineral Compounds from Nymphaea alba Wild-Grown in Danube Delta Biosphere
Authors: Cudalbeanu Mihaela , Ghinea Ioana Otilia , Furdui Bianca , Dah-Nouvlessounon Durand , Raclea Robert , Costache Teodor , Cucolea Iulia Elena , Urlan Florentina , Dinica Rodica Mihaela
Published: May 2018

Nymphaea alba is an aquatic flowering plant from the Nymphaeaceae family that has been used for hundreds of years in traditional herbal medicine. The plant is characterized by different phytochemicals, depending on the geographical location. Herein, we have carried out, for the first time, the separation and HPLC-MS/MS identification of some antioxidant compounds, such as polyphenols and flavonoids from N. alba extracts from the Danube Delta Biosphere, and investigated their possible antiradical properties. An ultrasonic method has been exhaustively used for the extraction of the antioxidant compounds from the different anatomic parts of N. alba (fruit, flower, leaf, stem, and root). The extracts that were obtained using ultrasound irradiation showed a large polyphenol (19.42 mg EqGA/100 mg extract) and flavonoid (0.97 mg EqQ/100 mg extract) content. The fruit and flower extracts showed the highest antioxidant activity index (AAI). Among the 27 phytochemical compounds identified in all of the N. alba extracts, rutin and p-coumaric acid were found as the major components. The content of macroelements and microelements in N. alba extracts were compared, and it was found that their concentrations depend on the different anatomic parts of the plant. This research contributes to the study of Nymphaeaceae family, being the first exhaustive phytochemical study of N. alba from a wild population in Romania.
Synthesis, Design, and Structure–Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase
Authors: Xu Le , Li Wenjie , Diao Yanyan , Sun Hongxia , Li Honglin , Zhu Lili , Zhou Hongchang , Zhao Zhenjiang
Published: May 2018

The inhibition of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) potentially represents a new treatment option for malaria, as P. falciparum relies entirely on a de novo pyrimidine biosynthetic pathway for survival. Herein, we report a series of pyrimidone derivatives as novel inhibitors of PfDHODH. The most potent compound, 26, showed high inhibition activity against PfDHODH (IC50 = 23 nM), with >400-fold species selectivity over human dihydroorotate dehydrogenase (hDHODH). The brand-new inhibitor scaffold targeting PfDHODH reported in this work may lead to the discovery of new antimalarial agents.
Performance Comparisons of Polymer Semiconductors Synthesized by Direct (Hetero)Arylation Polymerization (DHAP) and Conventional Methods for Organic Thin Film Transistors and Organic Photovoltaics
Authors: Hendsbee Arthur D. , Li Yuning
Published: May 2018

C-C bond forming reactions are central to the construction of π-conjugated polymers. Classical C-C bond forming reactions such as the Stille and Suzuki coupling reactions have been widely used in the past for this purpose. More recently, direct (hetero)arylation polymerization (DHAP) has earned a place in the spotlight with an increasing number of π-conjugated polymers being produced using this atom-economic and more sustainable chemistry. As semiconductors in organic electronics, the device performances of the polymers made by DHAP are of great interest and importance. This review compares the device performances of some representative π-conjugated polymers made using the DHAP method with those made using the conventional C-C bond forming reactions when they are used as semiconductors in organic thin film transistors (OTFTs) and organic photovoltaics (OPVs).
Lanthanide-Doped Ceria Nanoparticles as Backside Coaters to Improve Silicon Solar Cell Efficiency
Authors: Hajjiah Ali , Samir Effat , Shehata Nader , Salah Mohamed
Published: May 2018

This paper introduces lanthanide-doped ceria nanoparticles as silicon solar cell back-side coaters, showing their influence on the solar cell efficiency. Ceria nanoparticles can be synthesized to have formed oxygen vacancies (O-vacancies), which are associated with converting cerium ions from the Ce4+ state ions to the Ce3+ ones. These O-vacancies follow the rule of improving silicon solar cell conductivity through a hopping mechanism. Besides, under near-ultra violet (near-UV) excitation, the reduced trivalent cerium Ce3+ ions are directly responsible for down converting the un-absorbed UV wavelengths to a resultant green photo-luminescence emission at ~520 nm, which is absorbed through the silicon solar cell’s active layer. Adding lanthanide elements such as Neodymium “Nd” as ceria nanoparticle dopants helps in forming extra oxygen vacancies (O-vacancies), followed by an increase in the number of Ce4+ to Ce3+ ion reductions, thus enhancing the conductivity and photoluminescence down conversion mechanisms. After introducing lanthanide-doped ceria nanoparticles on a silicon solar cell surface, a promising enhancement in the behavior of the solar cell current-voltage curve is observed, and the efficiency is improved by about 25% of its initial value due to the mutual impact of improving both electric conductivity and optical conversions.
Interaction of Poly(l-lysine)/Polysaccharide Complex Nanoparticles with Human Vascular Endothelial Cells
Authors: Weber Dominik , Torger Bernhard , Richter Karsten , Nessling Michelle , Momburg Frank , Woltmann Beatrice , Müller Martin , Schwartz-Albiez Reinhard
Published: May 2018

Angiogenesis plays an important role in both soft and hard tissue regeneration, which can be modulated by therapeutic drugs. If nanoparticles (NP) are used as vectors for drug delivery, they have to encounter endothelial cells (EC) lining the vascular lumen, if applied intravenously. Herein the interaction of unloaded polyelectrolyte complex nanoparticles (PECNP) composed of cationic poly(l-lysine) (PLL) and various anionic polysaccharides with human vascular endothelial cells (HUVEC) was analyzed. In particular PECNP were tested for their cell adhesive properties, their cellular uptake and intracellular localization considering composition and net charge. PECNP may form a platform for both cell coating and drug delivery. PECNP, composed of PLL in combination with the polysaccharides dextran sulfate (DS), cellulose sulfate (CS) or heparin (HEP), either unlabeled or labeled with fluorescein isothiocyanate (FITC) and either with positive or negative net charge were prepared. PECNP were applied to human umbilical cord vein endothelial cells (HUVEC) in both, the volume phase and immobilized phase at model substrates like tissue culture dishes. The attachment of PECNP to the cell surface, their intracellular uptake, and effects on cell proliferation and growth behavior were determined. Immobilized PECNP reduced attachment of HUVEC, most prominently the systems PLL/HEP and PLL/DS. A small percentage of immobilized PECNP was taken up by cells during adhesion. PECNP in the volume phase showed no effect of the net charge sign and only minor effects of the composition on the binding and uptake of PECNP at HUVEC. PECNP were stored in endosomal vesicles in a cumulative manner without apparent further processing. During mitosis, internalized PECNP were almost equally distributed among the dividing cells. Both, in the volume phase and immobilized at the surface, PECNP composed of PLL/HEP and PLL/DS clearly reduced cell proliferation of HUVEC, however without an apparent cytotoxic effect, while PLL/CS composition showed minor impairment. PECNP have an anti-adhesive effect on HUVEC and are taken up by endothelial cells which may negatively influence the proliferation rate of HUVEC. The negative effects were less obvious with the composition PLL/CS. Since uptake and binding for PLL/HEP was more efficient than for PLL/DS, PECNP of PLL/HEP may be used to deliver growth factors to endothelial cells during vascularization of bone reconstitution material, whereas those of PLL/CS may have an advantage for substituting biomimetic bone scaffold material.
Antibacterial Activity of Nanomaterials
Authors: Díez-Pascual Ana María
Published: May 2018

n/a
Nanoparticle-Mediated Therapeutic Agent Delivery for Treating Metastatic Breast Cancer—Challenges and Opportunities
Authors: Li Yunfei , Humphries Brock , Yang Chengfeng , Wang Zhishan
Published: May 2018

Breast cancer (BC) is the second leading cause of cancer-related death in American women and more than 90% of BC-related death is caused by metastatic BC (MBC). This review stresses the limited success of traditional therapies as well as the use of nanomedicine for treating MBC. Understanding the biological barriers of MBC that nanoparticle in vivo trafficking must overcome could provide valuable new insights for translating nanomedicine from the bench side to the bedside. A view about nanomedicine applied in BC therapy has been summarized with their present status, which is gaining attention in the clinically-applied landscape. The progressions of drug/gene delivery systems, especially the status of their preclinical or clinical trials, are also discussed. Here we highlight that the treatment of metastasis, in addition to the extensively described inhibition of primary tumor growth, is an indispensable requirement for nanomedicine. Along with more innovations in material chemistry and more progressions in biology, nanomedicine will constantly supply more exciting new approaches for targeted drug/gene delivery against MBC.
Microstructure and Thermal Reliability of Microcapsules Containing Phase Change Material with Self-Assembled Graphene/Organic Nano-Hybrid Shells
Authors: Wang Xianfeng , Guo Yandong , Su Junfeng , Zhang Xiaolong , Han Ningxu , Wang Xinyu
Published: May 2018

In recent decades, microcapsules containing phase change materials (microPCMs) have been the center of much attention in the field of latent thermal energy storage. The aim of this work was to prepare and investigate the microstructure and thermal conductivity of microPCMs containing self-assembled graphene/organic hybrid shells. Paraffin was used as a phase change material, which was successfully microencapsulated by graphene and polymer forming hybrid composite shells. The physicochemical characters of microPCM samples were investigated including mean size, shell thickness, and chemical structure. Scanning electron microscope (SEM) results showed that the microPCMs were spherical particles and graphene enhanced the degree of smoothness of the shell surface. The existence of graphene in the shells was proved by using the methods of X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), and atomic force microscopy (AFM). It was found that graphene hybrid shells were constructed by forces of electric charge absorption and long-molecular entanglement. MicroPCMs with graphene had a higher degradation temperature of 300 °C. Graphene greatly enhanced the thermal stability of microPCMs. The thermal conductivity tests indicated that the phase change temperature of microPCMs was regulated by the graphene additive because of enhancement of the thermal barrier of the hybrid shells. Differential scanning calorimetry (DSC) tests proved that the latent thermal energy capability of microPCMs had been improved with a higher heat conduction rate. In addition, infrared thermograph observations implied that the microPCMs had a sensitivity response to heat during the phase change cycling process because of the excellent thermal conductivity of graphene.
Prevention and Treatment of Intestinal Failure-Associated Liver Disease in Children
Authors: Norsa Lorenzo , Nicastro Emanuele , Di Giorgio Angelo , Lacaille Florence , D’Antiga Lorenzo
Published: May 2018

Intestinal failure-associated liver disease (IFALD) is a threatening complication for children on long-term parenteral nutrition because of intestinal failure. When progressive and intractable, it may jeopardize intestinal rehabilitation and lead to combined liver and intestinal transplantation. The institution of dedicated intestinal failure centers has dramatically decreased the incidence of such complication. IFALD may rapidly fade away if very early management aimed at preventing progression to end-stage liver disease is provided. In this review, we address the etiology and risk factors of IFALD in order to introduce pillars of prevention (nutritional management and catheter-related infections control). The latest evidence of therapeutic strategies, such as medical and surgical treatments, is also discussed.
Lorentz Invariance and the Zero-Point Stress-Energy Tensor
Authors: Visser Matt
Published: May 2018

Some 67 years ago (1951), Wolfgang Pauli noted that the net zero-point energy density could be set to zero by a carefully fine-tuned cancellation between bosons and fermions. In the current article, I will argue in a slightly different direction: the zero-point energy density is only one component of the zero-point stress energy tensor, and it is this tensor quantity that is in many ways the more fundamental object of interest. I shall demonstrate that Lorentz invariance of the zero-point stress energy tensor implies finiteness of the zero-point stress energy tensor, and vice versa. Under certain circumstances (in particular, but not limited to, the finite quantum field theories (QFTs)), Pauli’s cancellation mechanism will survive the introduction of particle interactions. I shall then relate the discussion to beyond standard model (BSM) physics, to the cosmological constant, and to Sakharov-style induced gravity.
Magnetic Nanoparticles Conjugated with Peptides Derived from Monocyte Chemoattractant Protein-1 as a Tool for Targeting Atherosclerosis
Authors: Kao Chung-Wei , Wu Po-Ting , Liao Mei-Yi , Chung I-Ju , Yang Kai-Chien , Tseng Wen-Yih , Yu Jiashing
Published: May 2018

Atherosclerosis is a multifactorial inflammatory disease that may progress silently for long period, and it is also widely accepted as the main cause of cardiovascular diseases. To prevent atherosclerotic plaques from generating, imaging early molecular markers and quantifying the extent of disease progression are desired. During inflammation, circulating monocytes leave the bloodstream and migrate into incipient lipid accumulation in the artery wall, following conditioning by local growth factors and proinflammatory cytokines; therefore, monocyte accumulation in the arterial wall can be observed in fatty streaks, rupture-prone plaques, and experimental atherosclerosis. In this work, we synthesized monocyte-targeting iron oxide magnetic nanoparticles (MNPs), which were incorporated with the peptides derived from the chemokine receptor C-C chemokine receptor type 2 (CCR2)-binding motif of monocytes chemoattractant protein-1 (MCP-1) as a diagnostic tool for potential atherosclerosis. MCP-1-motif MNPs co-localized with monocytes in in vitro fluorescence imaging. In addition, with MNPs injection in ApoE knockout mice (ApoE KO mice), the well-characterized animal model of atherosclerosis, MNPs were found in specific organs or regions which had monocytes accumulation, especially the aorta of atherosclerosis model mice, through in vivo imaging system (IVIS) imaging and magnetic resonance imaging (MRI). We also performed Oil Red O staining and Prussian Blue staining to confirm the co-localization of MCP-1-motif MNPs and atherosclerosis. The results showed the promising potential of MCP-1-motif MNPs as a diagnostic agent of atherosclerosis.
Computational Fluid Dynamics (CFD) Modelling and Application for Sterilization of Foods: A Review
Authors: Park Hyeon Woo , Yoon Won Byong
Published: May 2018

Computational fluid dynamics (CFD) is a powerful tool to model fluid flow motions for momentum, mass and energy transfer. CFD has been widely used to simulate the flow pattern and temperature distribution during the thermal processing of foods. This paper discusses the background of the thermal processing of food, and the fundamentals in developing CFD models. The constitution of simulation models is provided to enable the design of effective and efficient CFD modeling. An overview of the current CFD modeling studies of thermal processing in solid, liquid, and liquid-solid mixtures is also provided. Some limitations and unrealistic assumptions faced by CFD modelers are also discussed.
Rain Microstructure Parameters Vary with Large-Scale Weather Conditions in Lausanne, Switzerland
Authors: Ghada Wael , Buras Allan , Lüpke Marvin , Schunk Christian , Menzel Annette
Published: May 2018

Rain properties vary spatially and temporally for several reasons. In particular, rain types (convective and stratiform) affect the rain drop size distribution (DSD). It has also been established that local weather conditions are influenced by large-scale circulations. However, the effect of these circulations on rain microstructures has not been sufficiently addressed. Based on DSD measurements from 16 disdrometers located in Lausanne, Switzerland, we present evidence that rain DSD differs among general weather patterns (GWLs). GWLs were successfully linked to significant variations in the rain microstructure characterized by the most important rain properties: rain intensity (R), mass weighted rain drop diameter (Dm), and rain drop concentration (N), as well as Z = ARb parameters. Our results highlight the potential to improve radar-based estimations of rain intensity, which is crucial for several hydrological and environmental applications.
Cloud Classification in Wide-Swath Passive Sensor Images Aided by Narrow-Swath Active Sensor Data
Authors: Wang Hongxia , Xu Xiaojian
Published: May 2018

It is a challenge to distinguish between different cloud types because of the complexity and diversity of cloud coverage, which is a significant clutter source that impacts on target detection and identification from the images of space-based infrared sensors. In this paper, a novel strategy for cloud classification in wide-swath passive sensor images is developed, which is aided by narrow-swath active sensor data. The strategy consists of three steps, that is, the orbit registration, most matching donor pixel selection, and cloud type assignment for each recipient pixel. A new criterion for orbit registration is proposed so as to improve the matching accuracy. The most matching donor pixel is selected via the Euclidean distance and the square sum of the radiance relative differences between the recipient and the potential donor pixels. Each recipient pixel is then assigned a cloud type that corresponds to the most matching donor. The cloud classification of the Moderate Resolution Imaging Spectroradiometer (MODIS) images is performed with the aid of the data from Cloud Profiling Radar (CPR). The results are compared with the CloudSat product 2B-CLDCLASS, as well as those that are obtained using the method of the International Satellite Cloud Climatology Project (ISCCP), which demonstrates the superior classification performance of the proposed strategy.
Time and Memory Efficient Online Piecewise Linear Approximation of Sensor Signals
Authors: Grützmacher Florian , Beichler Benjamin , Hein Albert , Kirste Thomas , Haubelt Christian
Published: May 2018

Piecewise linear approximation of sensor signals is a well-known technique in the fields of Data Mining and Activity Recognition. In this context, several algorithms have been developed, some of them with the purpose to be performed on resource constrained microcontroller architectures of wireless sensor nodes. While microcontrollers are usually constrained in computational power and memory resources, all state-of-the-art piecewise linear approximation techniques either need to buffer sensor data or have an execution time depending on the segment’s length. In the paper at hand, we propose a novel piecewise linear approximation algorithm, with a constant computational complexity as well as a constant memory complexity. Our proposed algorithm’s worst-case execution time is one to three orders of magnitude smaller and its average execution time is three to seventy times smaller compared to the state-of-the-art Piecewise Linear Approximation (PLA) algorithms in our experiments. In our evaluations, we show that our algorithm is time and memory efficient without sacrificing the approximation quality compared to other state-of-the-art piecewise linear approximation techniques, while providing a maximum error guarantee per segment, a small parameter space of only one parameter, and a maximum latency of one sample period plus its worst-case execution time.
Real-Time Hand Position Sensing Technology Based on Human Body Electrostatics
Authors: Tang Kai , Li Pengfei , Wang Chuang , Wang Yifei , Chen Xi
Published: May 2018

Non-contact human-computer interactions (HCI) based on hand gestures have been widely investigated. Here, we present a novel method to locate the real-time position of the hand using the electrostatics of the human body. This method has many advantages, including a delay of less than one millisecond, low cost, and does not require a camera or wearable devices. A formula is first created to sense array signals with five spherical electrodes. Next, a solving algorithm for the real-time measured hand position is introduced and solving equations for three-dimensional coordinates of hand position are obtained. A non-contact real-time hand position sensing system was established to perform verification experiments, and the principle error of the algorithm and the systematic noise were also analyzed. The results show that this novel technology can determine the dynamic parameters of hand movements with good robustness to meet the requirements of complicated HCI.
Evaluation of Image Reconstruction Algorithms for Confocal Microwave Imaging: Application to Patient Data
Authors: Elahi Muhammad Adnan , O’Loughlin Declan , Lavoie Benjamin R. , Glavin Martin , Jones Edward , Fear Elise C. , O’Halloran Martin
Published: May 2018

Confocal Microwave Imaging (CMI) for the early detection of breast cancer has been under development for over two decades and is currently going through early-phase clinical evaluation. The image reconstruction algorithm is a key signal processing component of any CMI-based breast imaging system and impacts the efficacy of CMI in detecting breast cancer. Several image reconstruction algorithms for CMI have been developed since its inception. These image reconstruction algorithms have been previously evaluated and compared, using both numerical and physical breast models, and healthy volunteer data. However, no study has been performed to evaluate the performance of image reconstruction algorithms using clinical patient data. In this study, a variety of imaging algorithms, including both data-independent and data-adaptive algorithms, were evaluated using data obtained from a small-scale patient study conducted at the University of Calgary. Six imaging algorithms were applied to reconstruct 3D images of five clinical patients. Reconstructed images for each algorithm and each patient were compared to the available clinical reports, in terms of abnormality detection and localisation. The imaging quality of each algorithm was evaluated using appropriate quality metrics. The results of the conventional Delay-and-Sum algorithm and the Delay-Multiply-and-Sum (DMAS) algorithm were found to be consistent with the clinical information, with DMAS producing better quality images compared to all other algorithms.
Pulse Based Time-of-Flight Range Sensing
Authors: Sarbolandi Hamed , Plack Markus , Kolb Andreas
Published: May 2018

Pulse-based Time-of-Flight (PB-ToF) cameras are an attractive alternative range imaging approach, compared to the widely commercialized Amplitude Modulated Continuous-Wave Time-of-Flight (AMCW-ToF) approach. This paper presents an in-depth evaluation of a PB-ToF camera prototype based on the Hamamatsu area sensor S11963-01CR. We evaluate different ToF-related effects, i.e., temperature drift, systematic error, depth inhomogeneity, multi-path effects, and motion artefacts. Furthermore, we evaluate the systematic error of the system in more detail, and introduce novel concepts to improve the quality of range measurements by modifying the mode of operation of the PB-ToF camera. Finally, we describe the means of measuring the gate response of the PB-ToF sensor and using this information for PB-ToF sensor simulation.
Laser Spectroscopic Sensors for the Development of Anthropomorphic Robot Sensitivity
Authors: Bukin Oleg , Proschenko Dmitriy , Chekhlenok Alexey , Golik Sergey , Bukin Ilya , Mayor Alexander , Yurchik Victoriya
Published: May 2018

The development of underwater robotics sensitivity, which is based on the sensors of laser spectroscopy methods, have been discussed. The ways to improve Laser Induced Fluorescence (LIF) and Laser Induced Breakdown Spectroscopy (LIBS) methods were investigated in order to develop and create laser sensitivity for underwater robotics. A brief overview is done in the article, where LIF and LIBS spectroscopy in underwater robotics are used as spectroscopy sensors in order to investigate underwater environments by means of underwater vehicles. Limit of Detection (LoD) of oil and oil product solutions in the seawater have been detected by means of nanosecond and femtosecond spectroscopy LIF. All results, which had been received by laser pulses of different duration, were compared. The same experiments have been provided in order to measure concentrations of elements in the seawater and solutions by the LIBS method. It was discovered that the LoD of a group of elements was reduced when the femtosecond LIBS was used. Anthropomorphic complexes were under discussion in order to adopt laser spectroscopy sensors for underwater environments. The submersible module, which was constructed to investigate and examine laser spectroscopy sensors, has been described.
Electrolyte Magnetohydrondyamics Flow Sensing in an Open Annular Channel—A Vision System for Validation of the Mathematical Model
Authors: Valenzuela-Delgado Mónica , Flores-Fuentes Wendy , Rivas-López Moisés , Sergiyenko Oleg , Lindner Lars , Hernández-Balbuena Daniel , Rodríguez-Quiñonez Julio C.
Published: May 2018

Magnetohydrodynamics (MHD) is becoming more popular every day among developers of applications based on microfluidics, such as “lab on a chip” (LOC) and/or “micro-total analysis systems” (micro-TAS). Its physical properties enable fluid manipulation for tasks such as pumping, networking, propelling, stirring, mixing, and even cooling without the need for mechanical components, and its non-intrusive nature provides a solution to mechanical systems issues. However, these are not easy tasks. They all require precise flow control, which depends on several parameters, like microfluidics conductivity, the microfluidics conduit (channel) shape and size configuration, and the interaction between magnetic and electric fields. This results in a mathematical model that needs to be validated theoretically and experimentally. The present paper introduces the design of a 3D laminar flow involving an electrolyte in an annular open channel driven by a Lorentz force. For an organized description, first of all is provided an introduction to MHD applied in microfluidics, then an overall description of the proposed MHD microfluidic system is given, after that is focused in the theoretical validation of the mathematical model, next is described the experimental validation of the mathematical model using a customized vision system, and finally conclusions and future work are stated.
Comparison between Different Types of Sensors Used in the Real Operational Environment Based on Optical Scanning System
Authors: Flores-Fuentes Wendy , Miranda-Vega Jesús Elías , Rivas-López Moisés , Sergiyenko Oleg , Rodríguez-Quiñonez Julio C. , Lindner Lars
Published: May 2018

The present paper describes the experimentation in a controlled environment and a real environment using different photosensors, such as infrared light emitting diode (IRLED-as receiver), photodiode, light dependent resistor (LDR), and blue LED for the purpose of selecting those devices, which can be employed in adverse conditions, such as sunlight or artificial sources. The experiments that are described in this paper confirmed that the blue LED and phototransistor could be used as a photosensor of an Optical Scanning System (OSS), because they were less sensitive to sunlight radiation. Moreover, they are appropriate as reference sources that are selected for the experiment (blue LED flashlight and light bulb). The best experimental results that were obtained contained a digital filter that was applied to the output of the photosensor, which reduced the standard deviation for the best case for the phototransistor LED from 100.26 to 0.15. For the best case, using the blue LED, the standard deviation was reduced from 86.08 to 0.11. Using these types of devices the cost of the Optical Scanning System can be reduced and a considerable increase in resolution and accuracy.
Dynamical Properties of Postural Control in Obese Community-Dwelling Older Adults
Authors: Frames Christopher , Soangra Rahul , Lockhart Thurmon , Lach John , Ha Dong , Roberto Karen , Lieberman Abraham
Published: May 2018

Postural control is a key aspect in preventing falls. The aim of this study was to determine if obesity affected balance in community-dwelling older adults and serve as an indicator of fall risk. The participants were randomly assigned to receive a comprehensive geriatric assessment followed by a longitudinal assessment of their fall history. The standing postural balance was measured for 98 participants with a Body Mass Index (BMI) ranging from 18 to 63 kg/m2, using a force plate and an inertial measurement unit affixed at the sternum. Participants’ fall history was recorded over 2 years and participants with at least one fall in the prior year were classified as fallers. The results suggest that body weight/BMI is an additional risk factor for falling in elderly persons and may be an important marker for fall risk. The linear variables of postural analysis suggest that the obese fallers have significantly higher sway area and sway ranges, along with higher root mean square and standard deviation of time series. Additionally, it was found that obese fallers have lower complexity of anterior-posterior center of pressure time series. Future studies should examine more closely the combined effect of aging and obesity on dynamic balance.
Group Sparse Representation Based on Nonlocal Spatial and Local Spectral Similarity for Hyperspectral Imagery Classification
Authors: Yu Haoyang , Gao Lianru , Liao Wenzhi , Zhang Bing
Published: May 2018

Spectral-spatial classification has been widely applied for remote sensing applications, especially for hyperspectral imagery. Traditional methods mainly focus on local spatial similarity and neglect nonlocal spatial similarity. Recently, nonlocal self-similarity (NLSS) has gradually gained support since it can be used to support spatial coherence tasks. However, these methods are biased towards the direct use of spatial information as a whole, while discriminative spectral information is not well exploited. In this paper, we propose a novel method to couple both nonlocal spatial and local spectral similarity together in a single framework. In particular, the proposed approach exploits nonlocal spatial similarities by searching non-overlapped patches, whereas spectral similarity is analyzed locally within the locally discovered patches. By fusion of nonlocal and local information, we then apply group sparse representation (GSR) for classification based on a group structured prior. Experimental results on three real hyperspectral data sets demonstrate the efficiency of the proposed approach, and the improvements are significant over the methods that consider either nonlocal or local similarity.
From Just War to Nuclear Pacifism: The Evolution of U.S. Christian Thinking about War in the Nuclear Age, 1946–1989
Authors: Rock Stephen R.
Published: May 2018

During the Cold War, two basic schools of thought emerged among U.S. Christian leaders and ethicists concerning the implications of the nuclear revolution for the use of force by the United States. The just war thinkers held that nuclear war could in fact be conducted within the bounds of traditional just war principles, particularly those of discrimination and proportionality. Since nuclear weapons could be used in war, it followed that they could and should be developed and produced for that purpose and for the purpose of deterrence. The nuclear pacifists held that nuclear war could not be conducted within the confines of traditional just war principles. Since by its nature nuclear war could not be moral, there was no reason for the development and production of nuclear weapons, except for the purpose of deterrence. And since nuclear deterrence required one to make threats of nuclear destruction that it would not be moral to carry out, and, moreover, carried unacceptable risks of miscalculation and inadvertent or accidental use of nuclear weapons, deterrence itself could not be justified, except perhaps as a temporary way station on the path to nuclear disarmament. Although the just war thinkers initially held sway, over time they became less dominant. By the middle of the 1980s, the U.S. Catholic Church and most of the largest Mainline Protestant denominations had formally adopted a nuclear pacifist position. This essay chronicles the victory of nuclear pacifism in these churches, explains it as a reaction to the nuclear weapons and doctrine advocated by the just war thinkers, and implemented by the U.S. government and military, as well as other events and trends in American society, and inquires as to whether or not the just war thinkers and nuclear pacifists influenced the course of U.S. policy.
An Integrated Multi-Criteria Decision Making Model and AHP Weighting Uncertainty Analysis for Sustainability Assessment of Coal-Fired Power Units
Authors: Wu Dianfa , Yang Zhiping , Wang Ningling , Li Chengzhou , Yang Yongping
Published: May 2018

The transformation of the power generation industry from coal-based to more sustainable energy sources is an irreversible trend. In China, the coal-fired power plant, as the main electric power supply facility at present, needs to know its own sustainability level to face the future competition. A hybrid multi-criteria decision making (MCDM) model is proposed in this paper to assess the sustainability levels of the existing Chinese coal-fired power units. The areal grey relational analysis (AGRA) method is involved in the hybrid model, and a combined weighting method is used to determine the priorities of the criteria. The combining weight fuses the fuzzy rough set (FRS) and entropy objective weighting method together with the analytic hierarchy process (AHP) subjective weighting method by game theory. Moreover, an AHP weighting uncertainty analysis using Monte Carlo (MC) simulation is introduced to measure the uncertainty of the results, and a 95 percent confidence interval (CI) is defined as the uncertainty measurement of the alternatives. A case study about eight coal-fired power units is carried out with a criteria system, which contains five aspects in an operational perspective, such as the flexibility, economic, environmental, reliability and technical criterion. The sustainability assessment is performed at the unit level, and the results give a priority rank of the eight alternatives; additionally, the uncertainty analysis supplies the extra information from a statistical perspective. This work expands a novel hybrid MCDM method to the sustainability assessment of the power generation systems, and it may be a benefit to the energy enterprises in assessing the sustainability at the unit level and enhance its ability in future sustainable development.
Built Form and Community Building in Residential Neighbourhoods: A Case Study of Physical Distance in Subiaco, Western Australia
Authors: Swapan Abu Yousuf , Bay Joo Hwa , Marinova Dora
Published: May 2018

With physical and social aspects being inseparable within urban environments, design for sustainability needs to include the link between the distance and sense of community. However, only a few studies examine residential suburbs and specifically focus on the physical and social interactions occurring within the streets and adjacent to them spaces, such as verges, sidewalks and front yards. Using a case study method, including observation and a perception-based survey in the inner-city suburb of Subiaco in Perth, Western Australia, this investigation opens up a new understanding of physical distance and social interaction. It develops a novel typology of physical distances and social closeness within a residential neighbourhood which allows better conceptualising the sense of community for achieving integrated sustainability.
Multiple, Independent T Cell Lymphomas Arising in an Experimentally FIV-Infected Cat during the Terminal Stage of Infection
Authors: Murphy Brian , Eckstrand Christina , Castillo Diego , Poon Andre , Liepnieks Molly , Harmon Kristy , Moore Peter
Published: May 2018

Our laboratory has serially reported on the virologic and immunopathologic features of a cohort of experimental feline immunodeficiency virus (FIV)-infected cats for more than eight years. At 8.09 years post infection (PI), one of these animals entered the terminal stage of infection, characterized by undulating hyperthermia, progressive anorexia, weight loss, and pancytopenia; the animal was not responsive to therapeutic interventions, necessitating euthanasia six weeks later (8.20 years PI). Subsequent analyses indicated that neoplastic lymphocytes infiltrated multiple cervical lymph nodes and a band-like region of the mucosal lamina propria within a segment of the intestine. Immunohistochemistry and T cell clonality testing determined that the nodal and intestinal lesions were independently arising from CD3 T cell lymphomas. In-situ RNA hybridization studies indicated that diffuse neoplastic lymphocytes from the cervical lymph node contained abundant viral nucleic acid, while viral nucleic acid was not detectable in lymphocytes from the intestinal lymphoma lesion. The proviral long terminal repeat (LTR) was amplified and sequenced from multiple anatomic sites, and a common clone containing a single nucleotide polymorphism was determined to be defective in response to phorbol myristate acetate (PMA)-mediated promoter activation in a reporter gene assay. This assay revealed a previously unidentified PMA response element within the FIV U3 region 3’ to the TATA box. The possible implications of these results on FIV-lymphoma pathogenesis are discussed.
Managing Salinity in Upper Colorado River Basin Streams: Selecting Catchments for Sediment Control Efforts Using Watershed Characteristics and Random Forests Models
Authors: Tillman Fred D. , Anning David W. , Heilman Julian A. , Buto Susan G. , Miller Matthew P.
Published: May 2018

Elevated concentrations of dissolved-solids (salinity) including calcium, sodium, sulfate, and chloride, among others, in the Colorado River cause substantial problems for its water users. Previous efforts to reduce dissolved solids in upper Colorado River basin (UCRB) streams often focused on reducing suspended-sediment transport to streams, but few studies have investigated the relationship between suspended sediment and salinity, or evaluated which watershed characteristics might be associated with this relationship. Are there catchment properties that may help in identifying areas where control of suspended sediment will also reduce salinity transport to streams? A random forests classification analysis was performed on topographic, climate, land cover, geology, rock chemistry, soil, and hydrologic information in 163 UCRB catchments. Two random forests models were developed in this study: one for exploring stream and catchment characteristics associated with stream sites where dissolved solids increase with increasing suspended-sediment concentration, and the other for predicting where these sites are located in unmonitored reaches. Results of variable importance from the exploratory random forests models indicate that no simple source, geochemical process, or transport mechanism can easily explain the relationship between dissolved solids and suspended sediment concentrations at UCRB monitoring sites. Among the most important watershed characteristics in both models were measures of soil hydraulic conductivity, soil erodibility, minimum catchment elevation, catchment area, and the silt component of soil in the catchment. Predictions at key locations in the basin were combined with observations from selected monitoring sites, and presented in map-form to give a complete understanding of where catchment sediment control practices would also benefit control of dissolved solids in streams.
Constructed Wetlands: A Review on the Role of Radial Oxygen Loss in the Rhizosphere by Macrophytes
Authors: Wang Qian , Hu Yanbiao , Xie Huijun , Yang Zhongchen
Published: May 2018

Constructed wetlands (CWs) are extensively used as an economical and environmentally friendly sewage treatment under ecological engineering technology. Knowledge of the oxygen in the rhizosphere is of primary importance in understanding the function and regulation of microbial communities and macrophytes. Numerous studies on radial oxygen loss (ROL) have greatly elucidated the mechanism of contaminant removal in CWs. The main sources of oxygen in CWs are atmospheric reoxygenation, macrophyte transmission, and artificial aeration. However, artificial aeration is very expensive, and atmospheric reoxygenation is limited. Therefore, ROL by macrophytes is an essential and economical approach for oxygen input in CWs. In this review, we attempted to study the role of macrophytes in CWs. We described the mechanism of ROL and summarized the methods for determining ROL. We also investigated the role of ROL in contaminant removal in CWs. This review will provide considerable useful information on the oxygen input of CWs.
Developing the Curriculum Content of Coastal and Maritime Tourism: Stakeholders' Perspective of the Sector-Specific Skills and Knowledge in Finland
Authors: Renfors Sanna-Mari
Published: May 2018

Investing in people is a prerequisite for sustainable growth and competitiveness in coastal and maritime tourism. Therefore, the development of coastal and maritime tourism curricula should be stimulated in higher education institutions. The aim of this article is to increase understanding
of the development needs of the content of the curriculum in coastal and maritime tourism in Finland from the stakeholders' perspective. The data were collected by semistructured interviews from 25 different tourism stakeholders affected by the decisions on curricula. In addition, the most
relevant and recent national, regional, and local reports and strategies were reviewed. All the data were analyzed with qualitative content analysis, which resulted in three categories describing the necessary curriculum content: 1) sustainable development of coastal and maritime tourism,
2) identification and use of coastal and marine resources, and 3) blue experience design. The results suggest that to meet the evolving needs of the stakeholders and to equip the graduates with sector-specific skills and knowledge, a themed curriculum in coastal and maritime tourism is needed.
Rapid transformation of sulfinate salts into sulfonates promoted by a hypervalent iodine(III) reagent
Authors: Deruer Elsa , Hamel Vincent , Blais Samuel , Canesi Sylvain
Published: May 2018

An alternative method for forming sulfonates through hypervalent iodine(III) reagent-mediated oxidation of sodium sulfinates has been developed. This transformation involves trapping reactive sulfonium species using alcohols. With additional optimization of the reaction conditions, the method appears extendable to other nucleophiles such as electron-rich aromatic systems or cyclic ethers through a ring opening pathway.
Nuclear Reactions in the Crusts of Accreting Neutron Stars
Authors: Lau R. , Beard M. , Gupta S. S. , Schatz H. , Afanasjev A. V. , Brown E. F. , Deibel A. , Gasques L. R. , Hitt G. W. , Hix W. R. , Keek L. , Möller P. , Shternin P. S. , Steiner A. W. , Wiescher M. , Xu Y.
Published: May 2018

X-ray observations of transiently accreting neutron stars during quiescence provide information about the structure of neutron star crusts and the properties of dense matter. Interpretation of the observational data requires an understanding of the nuclear reactions that heat and cool the crust during accretion and define its nonequilibrium composition. We identify here in detail the typical nuclear reaction sequences down to a depth in the inner crust where the mass density is

using a full nuclear reaction network for a range of initial compositions. The reaction sequences differ substantially from previous work. We find a robust reduction of crust impurity at the transition to the inner crust regardless of initial composition, though shell effects can delay the formation of a pure crust somewhat to densities beyond

. This naturally explains the small inner crust impurity inferred from observations of a broad range of systems. The exception are initial compositions with A ≥ 102 nuclei, where the inner crust remains impure with an impurity parameter of Q
imp ≈ 20 owing to the N = 82 shell closure. In agreement with previous work, we find that nuclear heating is relatively robust and independent of initial composition, while cooling via nuclear Urca cycles in the outer crust depends strongly on initial composition. This work forms a basis for future studies of the sensitivity of crust models to nuclear physics and provides profiles of composition for realistic crust models.
Embarquer avec les clowns à l’hôpital
Authors: Bodelet Claire
Published: May 2018

Résumé Croiser les clowns à l’hôpital ne laisse pas indifférent. Alors que les équipes médicales semblent s’habituer à leur remue-ménage, inventant même de nouvelles formes de collaboration, les familles parlent d’une impression d’être transportées ailleurs. Comment les clowns travaillent-ils avec les ambiances à l’hôpital ? En m’appuyant sur une enquête de terrain réalisée sur deux sites hospitaliers différents, dans des services où les clowns du Rire Médecin jouent chaque semaine, je montrerai comment les ambiances sont le résultat d’une série d’opérations effectuées en situation, aussi bien avec l’espace de l’hôpital qu’avec les différents « acteurs » qui l’habitent.
Dénoncer le programme
Authors: Cos Rafaël
Published: May 2018

Résumé La coalition de « gauche plurielle » conduite par Lionel Jospin entre 1997 et 2002 correspond au gouvernement ayant conduit les plus importantes politiques de privatisation sous la Cinquième République. Les enquêtes statistiques établissent pourtant que le nombre de privatisations est d’autant moins important que le gouvernement est de gauche et qu’il compte plusieurs partis en son sein. Pour éclairer cette contradiction, l’article teste l’hypothèse, a priori paradoxale, du « parties matter » . La sociologie des mobilisations programmatiques socialistes permet en effet de montrer que le bilan du gouvernement de gauche plurielle procède moins de contraintes purement exogènes qu’il ne trouve son ressort au sein du Parti socialiste lui-même.