bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and Validation of Diagnostic Models for Cervical Nerve Root Involvement Based on Items From the Patient Interview and Clinical Examination
Authors: Sleijser-Koehorst Marije L.S. , Coppieters Michel W. , Epping Rob , Rooker Servan , Verhagen Arianne P. , Heymans Martijn W. , Scholten-Peeters Gwendolyne G.M.
Published: November 2024

OBJECTIVE: To develop and internally validate diagnostic models for cervical nerve root involvement based on patient interview and clinical examination items.

DESIGN: Diagnostic predictive modeling study.

METHODS: People with a suspicion of cervical nerve root involvement (ie, radicular pain and/or radiculopathy) (N = 134) were included. Three diagnostic models (ie, patient interview items alone, clinical examination alone, and combined patient interview plus clinical examination) were developed using multivariable logistic regression analyses. For internal validation, we performed bootstrapping techniques (250 repetitions). The diagnostic accuracy (area under the curve [AUC]) and explained variance (Nagelkerke’s R2) of the models were assessed. An AUC of 0.7 or higher was considered adequate.

RESULTS: The patient interview model consisted of 2 items and showed an explained variance of 0.23 and an AUC of 0.74 (95% CI: 0.66, 0.81) after bootstrapping. The clinical examination model consisted of 2 items and had an explained variance of 0.29, and an AUC of 0.77 (95% CI: 0.69, 0.85) after internal validation. The combined model had an explained variance of 0.38 and an AUC of 0.82 (95% CI: 0.75, 0.89) after bootstrapping and consisted of the Spurling test (odds ratio [OR], 8.0; 95% CI: 3.1, 20.4), “Arm pain worse than neck pain” (OR, 4.8; 95% CI: 1.9, 11.8) and the patient-reported “Presence of paraesthesia and/or numbness” (OR, 2.8; 95% CI: 1.0, 7.8).

CONCLUSIONS: The combined model showed the best diagnostic accuracy to determine the likelihood of cervical nerve root involvement. External validation is required before implementing any diagnostic model. JOSPT Open 2025;3(2):1-7. Epub 26 November 2024. doi:10.2519/josptopen.2024.0082
Sociocultural dynamics: meanings and motivations
Authors: Shmakov V. S.
Published: November 2024

The article analyzes the processes of universalization and localization of the Eurasian socio-cultural space, factors determining the transitive state of culture and sociality of local communities. The processes of socio-economic modernization have a dominant influence on the formation of socio-cultural meanings and motives formed in the course of evolution and changes in the life structure of local communities, determining the confrontation between tradition and innovation. In the process of interaction and mutual influence of locality and globality, a system of socio-cultural markers, archetypes, generating norms of behavior, goals, foundations, values, determining the processes of integration and disintegration is formed. The progressive unification of the socio-cultural environment becomes the prevailing trend in the development of local communities, being reflected on the evolution of socio-culture, programming a break with traditional norms and meanings and the dominance of innovations in the socio-cultural space.
SELF-REGULATION OF LEARNING ACTIVITIES: COGNITIVE APPROACH
Authors: LOZHNIKOV A.E. , MARENKO V.A.
Published: November 2024

Self-regulation of learning is a set of skills that can be developed to help students manage themselves during the learning process. The purpose of the work is to build models that characterize the self-regulation of a student's cognitive activity. To achieve the goal, the following tasks are implemented: identifying factors influencing the phenomenon under study; construction and analysis of graphical and cognitive models of the problem, formulation of conclusions. As a result of the work, it was established that the factors “motivation” of educational activities and “flexibility” in actions are decisive for the process of self-regulation of educational activities. Additional control factors were identified: “practical implementation of intentions”, “initiative” of the student and “personality of the teacher”. The listed factors are recommended to be used by administrative structures to make management decisions in the field of education. The novelty of the study lies in the fact that most specialists study the processes of self-regulation using statistics. We used a cognitive approach, which allows us to obtain additional information about control factors and the relationships between them.
ON THE ORGANIZATION OF AUTOMATIC VERIFICATION OF ENGINEERING AND GEOMETRIC TASKS ON EDUCATIONAL INTERNET PLATFORMS
Authors: BOYKOV A.A.
Published: November 2024

The capabilities of educational platforms that support automatic verification of solutions to programming problems are analyzed using the «Stepik» as an example. An approach to organizing verification of solutions to engineering and geometric problems is proposed, which can be implemented using currently available capabilities. It consists of forming a text representation of a drawing or a 3D-model in the CAD system editor window, followed by insertion into the educational platform window and verification by a built-in Python subroutine or a remote server in the External grader mode. A Python script has been created that generates a description of a drawing for one class of descriptive geometry problems, and the fundamental possibility of verifying a solution by comparing it with a standard in the form of a sequence of text lines has been demonstrated.
METHODOLOGY OF VISUAL MODELING OF SOCIOTECHNOLOGICAL PROCESSES
Authors: KALININ V.S.
Published: November 2024

The study of the development of global civilizational processes in the modern sociotechnological environment makes it necessary to develop adequate means of its representation and modeling. The optimal approach is geospatial visualization, which allows you to consolidate heterogeneous information in a single space-time continuum. The paper briefly discusses possible visualization methods, and concludes that there is no universal approach. It is indicated that the optimal environment for geospatial visualization is the "Digital Earth", which allows to ensure the integrity of the image of the global situation and the possibility of using both the direct representation of geocontext a well as sign-mediated data.
STUDY OF VISUAL PERCEPTION OF DISCRETE COLOUR SCALES IN COMPLEX RELIEFS
Authors: LAPTEV M.V. , JANCHUS V.E.
Published: November 2024

The purpose of this paper is to test the hypothesis put forward about the perception of color discrete scales in complex reliefs when they are divided into 5, 7 and 9 segments. The study is based on an experiment conducted with the help of an eye tracking system, the results of which were visualized. The advantage of visual display of complex landforms divided into 5 and 7 segments was revealed, when maps with division into 9 segments were shown to be ineffective. For the stimuli offered in the experiment, the difference in color tone was not a statistically significant feature.
PROBLEMS OF DIGITAL SUPPORT FOR DESIGN OF HIGH-SPEED AMPHIBIOUS VESSELS AEROHYDRODYNAMICS
Authors: FEVRALSKIKH A.V.
Published: November 2024

The paper discusses the problems of digital support for the design of the aerohydrodynamic layout of a high-speed amphibious vessel intended for all-season operation. The main problems of designing the aerohydrodynamic layout and approaches to solving them using digital support methods based on numerical modeling of aerohydrodynamics are described. A mathematical model of numerical modeling of aerohydrodynamics is given, which allows taking into account the influence of the screen effect, deformation of the water surface, splash formation and icing on the aerohydrodynamic characteristics of the designed vessel layout. The results of testing and verification of the elements of the developed mathematical model are given using examples of solutions to problems of designing passenger ekranoplan layouts. An algorithm for designing the aerohydrodynamic layout of a high-speed amphibious vessel using digital support methods based on numerical modeling is proposed.
Atypical presentation and treatment of congenital cataract and temporal iridolenticular coloboma in a 43-year-old male
Authors: Kaur Rajwinder , Kaur Navreet , Kaur Harleen , Kaur Navdeep
Published: November 2024

Ocular coloboma occurs due to incomplete closure of the embryonic fissure in the 5th or 6th week of intrauterine life. Iris coloboma is characterised by a keyhole-shaped defect in the iris, typically located in the inferonasal quadrant. Temporal iris coloboma is a rare occurrence. Temporal iridolenticular coloboma is an uncommon structural anomaly within the iris that is sometimes linked to other ocular disorders, such as congenital cataracts. We describe a case study of a 43-year-old male patient who had a congenital cataract with temporal iridolenticular coloboma, which is not a common presentation. The aim is to report favourable outcomes of cataract surgery in patients with congenital cataracts associated with temporal iris coloboma with temporal lens coloboma. Phacoemulsification with intraocular lens implantation was done without any complications. Significant improvements in subjective visual function and visual acuity were seen in the post-operative follow-up.
Key determinants of postmenopausal osteoporosis: A mini-review of current insights
Authors: Jogi Mukesh Kumar , Sharma Rahul , Rahman Akhlaqur , Aglawe Aniket , Joshi Vibhor
Published: November 2024

Osteoporosis, a systemic skeletal disease characterized by low bone mineral density and heightened fracture risk, significantly affects postmenopausal women. This review examines the complex interplay of age, hormonal changes, lifestyle factors, and environmental influences, particularly air pollution, on postmenopausal osteoporosis. With over 200 million individuals impacted globally and an earlier peak incidence in India, there is an urgent need for focused research. This review focuses on estrogen’s crucial role in bone metabolism and how its deficiency leads to increased bone resorption. The adverse effects of air pollution, specifically particulate matter 2.5, on bone health, noting associations between elevated exposure and accelerated bone loss due to inflammation and oxidative stress, were also highlighted. The implications of climate change on osteoporosis risk, particularly regarding fluoride exposure linked to extreme weather patterns, represent a largely underexplored area of research. Explicitly elucidating these multifactorial influences will improve public health policies and promote proactive interventions to reduce osteoporosis risk in postmenopausal women.
Optimization of intraocular lens optical power calculation using artificial intelligence capabilities
Authors:   S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd branch, Volgograd, Russian Federation, Vinogradov A.R. , Balalin S.V. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd branch, Volgograd, Russian Federation,   Volgograd State Medical University, Volgograd, Russian Federation, Solodkova E.G. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd branch, Volgograd, Russian Federation,   Volgograd State Medical University, Volgograd, Russian Federation
Published: November 2024

Purpose. Development of a technology for optimal formula determination of the IOL required optical power, based on the artificial intelligence (AI) and the individual clinical characteristics of the patient’s eye.

Material and methods. A retrospective analysis of 1337 uncomplicated phacoemulsification with implantation of a monofocal IOL RAO100C (Rayner) was performed. For artificial intelligence training and models testing, a database was created containing 1080 clinical cases (1080 eyes); the process of filling the database was fully automated. The accuracy criterion for IOL prediction was the range of spheroequivalent (SE) values in the postoperative period <|0.5|.

Results. A retrospective analysis showed that in uncomplicated cataract surgery, the accuracy of the target refraction achievement is high and does not go beyond ±0.5 D. 16 artificial intelligence models were developed and tested, of which 4 were selected based on accuracy metrics – 1 model for each formula (Barrett, Haigis, Holladay 2, HofferQ). The best models turned out to be DecisionTreeClassifier. Validation of AI models was carried out by comparing the choice of IOL diopter between the AI and an expert. All models showed an advantage over the expert. A software interface for this service was developed and implemented.

Conclusion. A selective database has been created for training and testing artificial intelligence models that determine IOL optical power. A system has been developed to help a doctor make a decision to determine the required IOL optical power based on artificial intelligence, depending on the individual clinical characteristics of the patient’s eye. The high efficiency of the developed technology has been proven on a test model (90–95%). The program interface was developed and implemented.

Key words: IOL calculation, artificial intelligence
Kristina Gedgaudaitė. Memories of Asia Minor in Contemporary Greek Culture. Cham, Switzerland: Palgrave Macmillan, 2021
Authors: Никитина Инна
Published: November 2024

Кристина Гедгаудайте – молодая исследовательница-неоэллинист. Ее книга посвящена тому, как в современной Греции живут воспоминания о великой потере страны – о Малой Азии. Несмотря на то, что вся монография написана про память о конкретных исторических событиях, параграф под названием «Исторический контекст» появляется только в середине второй главы. В отличие от автора рецензируемой монографии, я бы хотела прояснить контекст в самом начале. Малая Азия (Μικρά Ασία), она же Анатолия1, – это полуостров, составляющий бόльшую часть современной Турции. К XIV веку Византия потеряла большую часть своих владений в Анатолии. После захвата Константинополя османами и падения Византийской империи в XV веке, уже весь полуостров стал территорией Османской империи, впоследствии – Турецкой Республики. При этом греки продолжали оставаться значимым этническим меньшинством в империи вплоть до начала ХХ века, когда и случились события, называемые на греческом языке не иначе как «Катастрофа» (Καταστροφή).
Текст на русском языке
О рисках инновационной деятельности
Authors: А. С. Кулагин
Published: November 2024

Проведен анализ организационно-экономических и специфических инновационных рисков, выявлены их причины и факторы, описаны рекомендуемые методы компенсации риска

An analysis of organizational and economic and specific innovative risks has been carried out, their causes and factors have been identified, and recommended methods of risk compensation are described
Efficient Crystallization of Apo Sirt2 for Small Molecule Soaking and Structural Analysis of Ligand Interactions
Authors: Friedrich Florian , Schiedel Matthias , Swyter Sören , Zhang Lin , Sippl Wolfgang , Schutkowski Mike , Einsle Oliver , Jung Manfred
Published: November 2024

The selectivity pocket is a key binding site for inhibitors of the NAD+-dependent lysine deacylase Sirtuin 2 (Sirt2), a promising drug target due to its involvement in diseases like cancer and neurodegeneration. While small molecule soaking could advance inhibitor development, the selectivity pocket is absent in current Sirt2 apo structures, and existing soaking systems like Sirt2-ADPribose (ADPR) suffer from disadvantageous crystal contacts that hinder ligand binding. We developed a method to rapidly generate high-quality Sirt2 apo crystals with an open selectivity pocket, suitable for high-throughput soaking experiments. The pocket formation is induced by seeding with a Sirtuin Rearranging ligand (SirReal) and is retained in the final apo structure without the presence of the ligand. Screening the Maybridge Ro3 library using fluorescence polarization and thermal shift assays yielded three novel Sirt2-fragment structures. These crystals can accommodate ligands at the acyl-lysine channel entrance and the cofactor binding site, as further confirmed with KT9 and NAD+, facilitating SAR studies and the optimization of inhibitors.
Lipophilicity Effects of Monofluorination at the Tertiary Aliphatic Carbon as a Function of alpha-Substituent
Authors: Melnykov Kostiantyn , Liashuk Oleksandr , Smyrnov Oleh , Lesyk Dmytro , Holota Yuliia , Borysko Petro , Yakubovskyi Viktor , Grygorenko Oleksandr
Published: November 2024

Effects of monofluorination at the tertiary aliphatic carbon on the compound’s lipophilicity were measured for a series of model 4-substituted piperidine-derived benzamides. It was found that the observed LogP values strongly depend on the nature of the alpha-substituent present at the C-4 position. In particular, the LogP difference increased with the increase in the substituent’s electronegativity (as described by the field effect). Using qualitative molecular electrostatic potential surface (MEPS) analysis, we suggested that the fluorine effect on the compound’s lipophilicity in the studied systems is defined by electronic distribution modulation at the neighboring atoms (especially Hydrogens).
Catch & Release of Al(I) at a Zinc Bis-Amide
Authors: Dankert Fabian , Sabater Enric , Salvador Pedro , Hevia Eva
Published: November 2024

[(HMDS)(Cp*)Al]2Zn (1) is an intriguing trimetallic zinc aluminyl for which reactivity and quantum chemical studies remain elusive. Through a combined experimental and computational approach 1 is revisited showcasing its reversible formation and reaction chemistry. As revealed computationally, the compound is prone to eliminate and transfer monomeric [AlCp*] – reminiscent of Schnöckels (AlCp*)4. Experimental validation is provided based on NMR studies which showcase the transfer of one and two equivalents of [AlCp*] possible with suitable trapping reagents. Without trapping reagents and thermal treatment of 1, Cp* transfer, Al(HMDS) release and decomposition pathways are induced. Disclosing complementary reactivity, sequential insertion of carbodiimides into 1 yields a series of carbene complexes through one- and twofold insertions. All transformations are followed by state-of-the-art chemical calculations to understand the chemical bonding and bimetallic cooperation between the elements Al and Zn in-depth.
Circadian rhythm of blood pressure and its correlations with short-term variability
Authors: Tykhonova T.M. , Lysenko N.V.
Published: November 2024

Background. Arterial hypertension (AH) is the main risk factor for cardiovascular (CV) and cerebrovascular diseases. To effectively prevent damage to target organs and reduce morbidity and mortality, adequate control of blood pressure (BP), including its variability (VAR), is important. The latter includes circadian, short-term, and long-term components, and VAR is best documented with out-of-office BP monitoring methods such as ambulatory BP monitoring (ABPM). The morning rise (MR) of BP is one of the components of variability, its disturbances are associated with an increased risk of stroke and CV events, regardless of the level of BP.

Purpose – the aim of the study was to study the relationship between the morning rise in blood pressure and the short-term blood pressure variability in patients with arterial hypertension.

Materials and Methods. The study included 169 patients with hypertension aged 43 to 78 years. Based on the results of ABPM, an assessment of the morning dynamics and short-term BP VAR were carried out. To assess the morning dynamics of blood pressure, the speed and amplitude of MR of systolic BP (SBP) and diastolic BP (DBP) were studied. SBP and DBP VAR were evaluated separately for day, night, and 24-hour periods using the SD, SDcorr, and ARV indices.

Results. In this open, non-randomized, cross-sectional study of patients with hypertension, a direct relationship between BP VAR and its morning dynamics was revealed – the increase in VAR was associated with greater amplitude and speed of BP MR. The established correlations were closer for MR amplitude than for MR speed, which allows to draw a conclusion about different pathogenesis mechanisms of their disorders and requires further study of this phenomenon. An increase in VAR SBP was associated not only with changes in the morning dynamics of SBP, but also with changes in the morning dynamics of DBP, and vice versa

Conclusions. ABPM should be an essential part of the management of hypertensive patients with an individualized approach to pharmacotherapy to achieve not only optimal 24-hour BP control, but also correction of elevated BP and excessive morning rise for the best cardiovascular and cerebrovascular protection.
Outcomes following the introduction of an interdisciplinary shared decision-making clinic for older patients with colorectal cancer
Authors: Jackson Alison , Shaw Christopher , O’Sullivan Brian , Govender Siva , Fischer Jesse
Published: November 2024

aim: Colorectal cancer (CRC) incidence is highest in older patients, who also have high rates of concurrent multimorbidity and frailty.
Shared decision making is important when deciding treatment. The aim of this study was to compare outcomes before and after
introduction of a shared decision-making (SDM) pathway, which includes an anaesthetist and geriatrician, for older patients with CRC
at Waikato Hospital.
method: Retrospective review of patients over 70 years of age considered for surgical resection was performed before (2018) and after
(2020) introduction of the SDM pathway. Primary outcome was days alive out of hospital (DAOH) at 12 months. Data were collected
on demographics, disease factors, specialist assessments, frailty and cognitive function, treatment, deviation from colorectal multidisciplinary
meeting (MDM) recommendation and outcomes.
results: In total, 169 patients were included. There were 103 males and the median age was 79 years (range 70–95). After the
introduction of the SDM clinic, more patients underwent non-operative management (16.1% vs 4.9%, p=0.02) and had management
that deviated from MDM recommendation (18.4% vs 4.9%, p=0.01). DAOH was marginally higher after introduction of the SDM clinic
(358 vs 352, p=0.02). There was no difference in survival.
conclusion: An interdisciplinary SDM clinic for older patients with CRC is feasible in a tertiary hospital in New Zealand and may
increase non-operative management and DAOH without impacting overall survival.
Transformation of the activities of law enforcement entities in the economic sphere (part 1)
Authors: Grytsyshen D. , Sergiienko L. , Baranovska T.
Published: November 2024

The article examines the current aspects of the transformation of the system of law enforcement bodies and state authorities in the conditions of social transformations, which include the reform of criminal legislation, European integration processes and social changes. In particular, the article analyzes the diversity of law enforcement agencies in different countries, particularly in Central and Eastern Europe, and their specific role in ensuring national security and countering criminal offenses. Approaches to the organization of communication between law enforcement agencies and international police organizations, as well as the possibility of creating joint international investigative teams for effective investigation of cross-border crimes, were studied. The article also highlights various concepts and features of law enforcement agencies based on research by various scientists, taking into account the specifics of security systems in different countries. The activity of law enforcement agencies in the countries of Central and Eastern Europe is analyzed and the lack of a unified approach to the structure of the law enforcement system in the countries of the European Union is indicated.
Clinical Implications of Eosinopenia in Adult Brucellosis Patients
Authors: Yang Luxuan , Xiao Dan , Zhu Chuanwu , Wang Haiyan , Zhang Wenyong , Chang Jianguo , Liu Meiqin , Shen Xiujuan
Published: November 2024

Objective: To analyze the differences between eosinopenia and non-eosinopenia brucellosis patients in depth. Methods: Medical records of brucellosis patients admitted to the Affiliated Infectious Diseases Hospital of Soochow University between January 1, 2013, and December 31, 2023, were reviewed retrospectively. Patients were categorized into an eosinopenia group and a non-eosinopenia group based on pre-treatment eosinophil levels. A nonparametric test was performed to estimate the differences between the two groups. Results: Among the 125 patients, 66 (52.80%) experienced eosinopenia. Patients with eosinopenia were older (52.09 ± 15.63 years vs. 46.08 ± 16.39 years, P = 0.024), had a higher proportion of hypertension (21.21% vs. 6.78%, P = 0.024), and exhibited a greater likelihood of complications (75.76% vs. 35.59%, P = 0.000), particularly hematological (68.18% vs. 23.73%, P = 0.000) and relapse (19.70% vs. 6.78%, P = 0.040). The eosinopenia group also showed higher levels of ALT (29.00 vs. 20.00, P = 0.003), AST (29.00 vs. 22.00, P = 0.037), and LOS (17.50 vs. 12.00, P = 0.000). Among certain inflammatory indicators related to brucellosis, the eosinopenia group demonstrated lower levels, such as MPV (9.75 vs. 10.70, P = 0.000), MLR (0.28 vs. 0.36, P = 0.002), and SIRI (0.67 vs. 1.03, P = 0.004). Conclusion: Brucellosis patients with eosinopenia differed in clinical manifestations and prognosis. Monitoring eosinophils may provide better prognostic assessment and suggest potential new treatment options.
Integrating Task-Based Language Teaching with Islamic Values: A Case Study in an Indonesian Islamic Junior High School
Authors: Soleh Muhammad Badrus , Salija Kisman , Sahril Sahril
Published: November 2024

The current research is a case study of Task-based English Language Teaching in an Islamic Junior High School (MTs) in Indonesia. The main objective of this study was to explore the implementation of Task-based English Language Teaching at an Indonesian Islamic Junior High School, MTs Negeri 3 Demak. The study was conducted on an English teacher and 32 students of MTs Negeri 3 Demak. To gather data, questionnaires, observation, and interviews were used. The researcher used qualitative data analysis to analyze the results of this study. The collected data showed that the implementation of the lesson was well-implemented and conducted in three phases. They were the opening activity, main activity and closing activity. The findings reveal that TBLT was implemented effectively across three phases: pre-task, task cycle, and language focus, with Islamic principles interwoven throughout each stage of the instructional process. This approach enhanced students’ engagement and language proficiency, promoting meaningful communication while reinforcing cultural and moral values. The study underscores the potential of TBLT to serve as a pedagogical tool in religious educational contexts, offering valuable insights for educators and policymakers on integrating language instruction with cultural and ethical dimensions.
Kajian Tepung Jagung yang Dipragelatinisasi Dilanjutkan Fermentasi Terhadap Kadar Glukosa Darah Mencit Yang Diinduksi Aloksan
Authors: Pratiwi Rizky Indah , Taufiq Nurkhaerani , Yanto Subari , Sukainah Andi , Putra Reski Praja
Published: November 2024

This study aims to determine the effect of modified corn flour through the pragelatinization process followed by Lactic Acid Bacteria (LAB) fermentation on lowering blood sugar levels. This study uses a quantitative description method in the form of experiments by comparing the average value of the mice group given the treatment. he first stage involves mice being grouped into 3 groups, each group contains 7 mice, adapted for 14 days, and measuring blood sugar levels before treatment. The second stage is feeding and treatment for 21 days, standard feed without alloxan injection as a negative control, standard feed with alloxan injection as a positive control, and feed containing modified corn flour through the process of pragelatinization and lactic acid fermentation with alloxan injection as a treatment group. The last stage is the measurement of blood sugar levels on the 21st day. The data analysis techniques used in this study were a normality test and a homogeneity test using IBM SPSS Statistics version 25, followed by a quantitative description in the form of experiments by comparing the mean values of the mice groups given treatment. T he results showed that feed containing modified corn flour through pragelatinization and fermentation of lactic acid bacteria had an effect on reducing blood sugar levels in mice. The group of mice that were given feed containing modified corn flour had lower blood sugar levels compared to the group of mice given standard feed (positive control), obtained at 127 mg/dl with a resulting mice body weight of 23.06 g, and feed consumption of 13.66 g.
Karakteristik Produk Olahan Sarabba Bubuk Instan dengan Penambahan Ketumbar (Coriandrum Sativum) Menggunakan Metode Kristalisasi
Authors: Asni Andi , Salfiana Salfiana , Muhanniah Muhanniah
Published: November 2024

Sarabbba is a local drink that is known among the Bugis-Makassar community, South Sulawesi. This drink is popular with many people because it provides a refreshing effect and warms the body. Various modifications need to be made to promote this traditional drink, one of which is by adding spices such as coriander which is also recognized as having several health benefits. The various minerals found in coriander seeds (Coriandrum sativum) function as flavonoids,bone minerals,yield and help maintain proper blood pressure. The aim of this research was to determine the effect of adding coriander to instant sarabba powder on product moisture content metrics and organoleptic tests. In this study, three treatments the addition of five grams, ten grams, and fifteen grams of coriander were used three times each. ANOVA was used to evaluate research data. Duncan's multiple range test is used to ensure that there are real differences between treatments if the analysis shows that there are differences between treatments. Empirical studies show that the water content, yield and color produced are not significantly influenced by instant sarabba powder. The addition of 5 grams of coriander with an average color of 4.12, aroma of 4.11 and taste of 4.07 was the best treatment in terms of organoleptics.
pH dan Suhu Optimum Aktivitas Enzim Amilase Kapang Termofilik dari Hot Spring Sulili
Authors: Indrayani Indrayani , Hambali Amiruddin , Jusran Jusran , Putra Reski Praja
Published: November 2024

Enzyme activity is greatly influenced by several factors including incubation time, temperature, and pH. This study aimed to determine the optimum pH and temperature of amylase enzyme activity of mold PSA 02 (5) isolated from Sulili hot spring, Pinrang Regency, South Sulawesi, Indonesia. This study was conducted in two stages, the first is determining the optimum pH of amylase enzyme activity where enzyme activity testing carried out at pH  4, 5, 6, 7, and 8. After determination of optimum pH, it continued to determine the optimum temperature of amylase enzyme activity at temperatures of 30, 40, 50, 60, 70, and 80oC. Determination of protein content using the Lowry method and determination of amylase enzyme activity using the Dinitrosalicilyc (DNS) method. The results of this study showed that the optimum pH of amylase enzyme activity is pH 4 with an enzyme activity value of 81.37 U/mL and a specific enzyme activity of 57.61 U/mg, while the optimum temperature of amylase enzyme activity is 50oC with a value of 81.44 U/mL and a specific enzyme activity of 57.74 U/mg. It is interesting to note that the amylase enzyme activity remains high up to a temperature of 80oC with a value of 81.20 U/mL. This study indicates that the amylase enzyme of mold isolate PSA 02 (5) is a thermostable enzyme up to a temperature of 80oC.
Pemanfaatan Ampas Kopi dan Arang Sekam Sebagai Media Tanam Dalam Pertumbuhan Tanaman Pakcoy (Brassica rapa L)
Authors: Indah Nur , Jamaluddin  , Lestari Nunik
Published: November 2024

Discarded coffee grounds are unfortunate, considering they have potential as a planting medium because they contain compounds that can support plant growth. Likewise, husk charcoal provides benefits because it has a porosity which can bind water and has the nutrients needed by pakcoy plants. This study aims to analyze the utilization of coffee grounds and husk charcoal as a planting medium for the growth of pakcoy plants. This study used a Completely Randomized Design (RAL) with six treatments and three replications. The treatments applied are control (M0) 100% soil, (M1) 40% soil + 10% coffee grounds + 50% husk charcoal, (M2) 40% soil + 20% coffee grounds + 40% husk charcoal, (M3) 40% soil + 30% coffee grounds + 30% husk charcoal, (M4) 40% soil + 40% coffee grounds + 20% husk charcoal, (M5) 40% soil + 50% coffee grounds + 10% husk charcoal. The changes observed were plant growth (plant height, number of leaves, length of roots, total fresh weight of the plant, dry weight and chlorophyll levels. The best planting medium in the M1 treatment is a combination of 40% soil + 10% coffee grounds, and +50% husk charcoal. From the study results, it can be concluded that coffee grounds and husk charcoal can be used as a planting medium for the growth of pakcoy plants
Pemanfaatan Molase Sebagai Substrat Acetobacter Xylinum Dalam Pengembangan Indikator Perubahan Kesegaran Buah Pisang
Authors: Mujahidah Anindita , Sukainah Andi , Indrayani
Published: November 2024

The sugar industry, in addition to producing cane sugar, also produces molasses which is the by-product of the sugar bleaching process. This waste still contains a lot of sugar ± 56%. and organic acids. The purpose of this study was to use molasses as a substrate for A. xylinum to be developed as an indicator of banana freshness. Cellulose produced from molasses substrate can be used as material for placing indicators. Freshness indicator has a working principle by observing changes in fruit freshness that are detected due to changes in pH in atmospheric conditions that are increasingly acidic as a result of metabolic activity. The freshness indicator of bananas from cellulose from 20% molasses substrate has different results of changes in the color of the freshness indicator. The method used in this research to apply the BTB compound to the cellulose sheet produced from molasses to be applied to 3 types of bananas (ambon, kepok and raja). Indicators affixed to plantains reach the indicator color change faster than ambon and kepok. Changes in this indicator are in line with physical and chemical changes in bananas which indicate a decrease in freshness. Both in terms of physical and chemical degradation.
Pengaruh Penambahan Tepung Rumput Laut (sargassum sp.) Pada Pakan Terhadap Pertumbuhan dan Sintasan Benih Ikan Nila (oreochromis niloticus)
Authors: Ahriani Andi Fifi , Syam Husain , Patang
Published: November 2024

Feed in the cultivation of tilapia seeds greatly affects the results of cultivation. The purpose of this study was to determine the effect of adding Sargassum sp. brown seaweed flour. on feed to the value of the food conversion ratio (FCR) of feed on tilapia fry. and Knowing the concentration of addition of Sargassum sp. on the growth and survival of tilapia fry. This study used the ANOVA test to compare the treatment with feeding with the addition of Sargassum sp. different in feed. The dose of feeding is 5% of the weight of the fish for 30 days of maintenance with the frequency of feeding 3 times a day. Parameters observed were weight gain, length, FCR (food conversion ratio) survival and water quality parameters, namely temperature, pH, DO, and ammonia. The results showed that treatment C was the best treatment, namely feed with the addition of Sargassum sp flour. 60g/1kg commercial feed. The highest C treatment experienced better growth and water quality
Kajian Minimum Inhibitor Concentration (MIC) dan Minimum Bactericidal Concentration (MBC) Ekstrak Kulit Terong Ungu (Solanum melongena L) Sebagai Pengembangan Antibakteri Herbal
Authors: Wahyuni Sri , Patang Patang , Putra Reski Praja
Published: November 2024

Purple eggplant skin contains flavonoid which are antibacterial compounds, but mostly just becomes waste, even though purple eggplant skin extract has  potential to be developed as herbal antibacterial. The purpose was to examine antibacterial activity, Minimum Inhibitor Concentration, and Minimum Bactericidal Concentration purple eggplant skin extract against pathogenic bacteria. Purple eggplant skin is extracted using the maceration method with 70% ethanol. The antibacterial activity test of purple eggplant skin extract was carried out by the method of diffusion using disc paper. Determination of MIC and MBC  is carried out by a dense dilution method in a pour plate, with concentrations used 0%, 1.56%, 3.13%, 6.25%, 12.5%, 25%, 50%, and 100%. The results of measuring the diameter of the inhibitory zone are Staphylococcus aureus (7.4 mm), Bacillus cereus (8.8 mm), Salmonella sp. (7.0 mm), Escherichia coli (1.7 mm). These results showed purple eggplant skin extract had a good ability to inhibit pathogenic bacteria, except E. coli (weak inhibitory power). MIC value of eggplant skin purple extract was obtained at 12.5% in each test bacteria. At this concentration, the number of colonies was able to be reduced to 1 Colony log/mL in all three test bacteria. MBC value of eggplant skin purple extract was obtained at 50%, at this concentration, no bacterial growth was found in the three test bacteria.
EL TRABAJO INCLUSIVO EN LAS EMPRESAS
Authors: Reyes Narciza , Gonzalez Cindy , Zhindón Byron , Bravo Daysy
Published: November 2024

A lo largo de los años se ha visto la problemática de la desigualdad en diferentes ámbitos y más aún cuando nos referimos al laboral, ya que es una problemática que trae consecuencias que afectan tanto a las familias, como al país entero, el desempleo disminuye la economía del país. Las personas con capacidades especiales, las mujeres y los jóvenes son los más afectados por la desigualdad, pero gracias a que, con el paso de los años, el país ha generado leyes y políticas para la inclusión de estas personas y puedan conseguir un empleo digno y justo según sus habilidades y capacidades. Con esta aplicación de leyes para las empresas claramente se ha conseguido que la inclusión sea un derecho para todas las personas. El objetivo del artículo, es conocer el avance de la inclusión a lo largo de estos últimos años y como ha ido fortaleciéndose en las empresas ecuatorianas, lo cual, es de suma importancia ya que con estos progresos disminuye el porcentaje de desempleo. El presente trabajo de enfoque cualitativo, basada en la revisión bibliográfica, con la búsqueda de artículos científicos de diferentes autores y normativas ecuatorianas vigentes, a través, de las bases digitales de la Universidad Católica De Cuenca, se consiguió una buena investigación
PLATAFORMA DE EDUCACIÓN VIRTUAL PARA FORTALECER LA ENSEÑANZA-APRENDIZAJE EN LA EDUCACIÓN GENERAL BÁSICA
Authors: Barrera Anthony , Mejia Joseline , Loayza Pauta Angie
Published: November 2024

En la actualidad, el nivel de Educación General Básica en todo el Ecuador ha sufrido un trastorno debido a la situación de emergencia sanitaria (Covid-19), en donde docentes y estudiantes han tenido que cambiar su metodología de enseñanza-aprendizaje, realizando sus actividades en línea (online) desde sus hogares. El problema de esta investigación radica en que la mayoría de las Unidades Educativas, especialmente de la ciudad de Cuenca-Ecuador, no disponen de una plataforma virtual que contribuya a sus procesos educativos, en momentos de emergencia (Covid-19), sin embargo, sudesconocimiento, aplicación y uso de estas herramientas tecnológicas han permitido que se forme una idea errónea en toda la sociedad, alejándose del verdadero concepto de una educación virtual. El objetivo de este estudio es diseñar un plan de mejora para tratar de mejorar la enseñanza-aprendizaje a través de una plataforma virtual que facilite las actividades a los estudiantes de este nivel. La metodología de esta investigación es de tipo descriptiva con enfoque cuantitativo, en donde se aplicará el método deductivo, por la misma razón se desarrollarán encuestas dirigidas a las autoridades, docentes y estudiantes de los centros educativos. Los resultados obtenidos de la investigación permiten el apoyo de plataformas virtuales para una eficiente enseñanza-aprendizaje a través del Plan de Mejora propuesto. Con el aporte de este estudio, se logrará que los Centros Educativos se alineen a un mayor nivel académico, formando estudiantes con estándares de calidad.
PROSPECTIVA DE LOS MECANISMOS EN LA DETECCIÓN DE FRAUDES FINANCIEROS
Authors: Hernandez Aros Ludivia , Jimenez Angie , Lemus José , Gutiérrez Fernando
Published: November 2024

Esta investigación aborda temas tanto generales como específicos en cuanto a definiciones, características y tipologías del fraude, especialmente enfocada hacia la prospectiva de los mecanismos de detección que existen en el mundo para combatir las acciones y prácticas delictivas que atentan contra la confianza y la buena fe de las personas. Como estudio descriptivo, aborda definiciones de variados autores en distintas bases de datos, y de esta manera, se identifica las publicaciones científicas analizadas a través del VOSviewer. Los análisis realizados a las publicaciones científicas muestran que los países europeos han sido los más interesados en avanzar y realizar investigaciones que logren detener este fenómeno mundial, al igual que en los países Latinoamericanos, por lo tanto, se hace necesario diseñar mecanismos avanzados contra el fraude con herramientas de punta como inteligencia artificial que ayude a minimizar riesgos organizacionales.
MODELOS DE TERRITORIOS SOLIDARIOS EN COLOMBIA
Authors: Rodríguez Daniela , Campos Juana , Olaya Sergio , Huamani Ruth
Published: November 2024

Dentro de esta investigación se recalca la importancia del desarrollo solidario dentro del entorno colombiano como un tipo de ayuda de cooperación hacia los modelos de integración. Esta investigación, cualitativa y descriptiva, se aboca al estudio y formas en las que se implementan los modelos solidarios en Colombia, destacando el impacto que tiene en la población colombiana y los diferentes acercamientos que pueden generarse a manera de alianzas estratégicas y políticas que puedan aportar a la población a modo de direccionamiento práctico. De estos modelos, no obstante, surge un interrogante acerca de si realmente se ha implementado algún modelo territorial para poder identificar la solidaridad en Colombia. La investigación busca identificar si las empresas son competitivas a niveles colombianos y latinoamericanos. Con base a los objetivos generales se quiere implementar los modelos de integración económica a nivel colombiano, proponiéndose documentar la existencia de modelos propios de Colombia y contrastarlos a nivel latinoamericano para tener resultados positivos. Como instrumento de recolección de datos se hizo uso de la encuesta, mediante la aplicación del cuestionario dirigido a los productores de mango del municipio de el Espinal Tolima. De manera teórica la economía solidaria es un baluarte que busca alternar los principios de la economía y la solidaridad a través del trabajo asociado, que se complementa con la inducción de diferentes entornos solidarios e instituciones económicas nacionales. Por otro lado, los estudios realizados por grandes personajes que idealizaron
ESTRATEGIAS DE MERCADEO PARA COMPAÑÍA DE TRANSPORTE INTRACANTONAL COMBINADO MEGASEVITRON CIA LTDA. Y SU IMPACTO EN LOS RATIOS FINANCIEROS EN EPOCAS DE PANDEMIA
Authors: Mendoza Plua Ana María , Argudo Garcia Gissela Esmeralda , Orellana Orellana Carlos Patricio , Orellana Orellana Edisón Fernando
Published: November 2024

El presente trabajo de investigación, permite que los socios de la compañía Megaservitron Cía. Ltda., del cantón La Troncal, establezcan estrategias adecuadas para mejorar la imagen financiera de la empresa; de esta manera el objetivo principal es determinar estrategias de mercadeo aplicables a la compañía Megasevitron con el fin de evaluar y mejorar la situación que está atravesando la compañía en épocas de pandemia, se realizó un diagnóstico de la situación actual, indagación de la situación económica y en conjunto con los estados financieros, se encontraron resultados no muy favorables.
GESTIÓN ESTRATÉGICA EN LA SEGURIDAD Y LA SALUD EN EL TRABAJO Y SUS HERRAMIENTAS DE CONTROL TECNOLÓGICAS
Authors: Alvarado Topón Jadira , Ordóñez Parra Janice
Published: November 2024

La Pandemia del COVID-19 causó severas consecuencias en el sector económico, debido a las restricciones de movilidad llevando a la disminución de la rentabilidad de las empresas, siendo el alquiler de vehículos, uno de los más afectados por la reducción de las visitas de turistas.
GESTIÓN ADMINISTRATIVA EN ESTABLECIMIENTOS COMERCIALES DEL RÉGIMEN DE PROPIEDAD HORIZONTAL BAJO EL ENFOQUE DE LA CONFIGURACIÓN ESTRATÉGICA DE MILES & SNOW: CASO CENTRO COMERCIAL PLAZA BOCAGRANDE, CARTAGENA
Authors: Villarreal Aguilar Luis Miguel , Bermejo Galán Jaime , Perez Porto Jazmin Rosa
Published: November 2024

La administración de propiedad horizontal con fines comerciales es un tema poco abordado por la academia, de hecho, son pocos los trabajos de grado que se han enfocado en el análisis de las propiedades para estos, la mayoría abordan la propiedad horizontal con fines familiares. Esto se debe, en parte, a que la ley que regula este tipo de propiedad hace mayor énfasis en la propiedad horizontal multifamiliar, y a que este tipo de propiedad abunda más en el mercado respecto a aquel que está destinado al comercio. Ahora bien, esto no quiere decir que la gestión administrativa en ambos tipos de propiedad no sea igual de desafiante. La propiedad horizontal con fines comerciales también requiere de procesos y enfoques de gestión administrativas que garantices su correcto funcionamiento y sostenibilidad. Por esto, el presente artículo explora un estudio de caso respecto a la gestión administrativa en establecimientos comerciales del régimen de propiedad horizontal bajo el enfoque de la configuración estratégica de Miles & Snow, dicho estudio fue realizado en el Centro Comercial Plaza Bocagrande en Cartagena, Colombia.
PENGARUH VARIASI WAKTU EKSTRAKSI TERHADAP KADAR SAPONIN TOTAL EKSTRAK AIR AKAR TEBU HITAM (Saccharum officinarum L.) SECARA SPEKTROFOTOMETRI UV-VIS
Authors: Sarwendah Adzkia Salsa , Lindawati Novena
Published: November 2024

Tanaman tebu hitam (Saccharum officinarum L.) merupakan tanaman tahunan yang sering dipakai sebagai obat, makanan, dan minuman. Rebusan akar tebu hitam memiliki berbagai efek farmakologis sebagai antibakteri, imunomodulator, dan antianemia karena adanya kandungan saponin. Tujuan dari penelitian ini untuk mengetahui kadar saponin total dengan variasi lama perebusan akar tebu hitam dengan menggunakan metode Spektrofotometri UV-Vis. Metode identifikasi senyawa saponin menggunakan metode busa dan pereaksi Liebermann-Burchard. Penetapan kadar saponin dengan metode Spectrofotometri UV-Vis pada panjang gelombang 543 nm dan operating time menit ke-15. Baku pembanding yang digunakan yaitu Diosgenin. Hasil identifikasi menunjukkan bahwa rebusan akar tebu hitam positif mengandung saponin. Hasil penetapan kadar saponin total dengan variasi lama perebusan 10 menit, 20 menit, dan 30 menit secara berurutan sebesar 1,123 mg DE/g dengan KV 0,679%, 2,086 mg DE/g dengan KV 0,276%, dan 2,933 mg DE/g dengan KV 0,196% ,lama rebusan 30 menit akar tebu hitam memiliki kadar saponin tertinggi. Uji Homogenity of Variences diperoleh nilai signifikansi 0,641 > 0,05. Uji Anova diperoleh nilai signifikansi 0,000 < 0,05, hal ini menunjukan adanya perbedaan yang signifikan antara kadar saponin akar tebu hitam dengan lama perebusan yang berbeda