bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of the features of angular stabilization of spacecraft with flexible struc-tural elements with the use mobile control methods
Authors:   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Alpatov A.P. , Wang C. ,   School of Automation, Northwestern Polytechnical University, Lu H. ,   School of Automation, Northwestern Polytechnical University, Chongqing Innovation Center, Northwestern Polytechnical University, Lapkhanov E.O. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine
Published: November 2024

The development of space power engineering is one of the well-known lines in rocket and space science and innovative technologies which attracts the attention of many scientists and researchers. Engineering solutions in space-based solar power plant design and wireless space-to-Earth and satellite-to-satellite power transmission and power spacecraft control methods have been substantiated theoretically to sufficient depth. However, despite this, there is a need to improve methods for and approaches to the development of an optimal design methodology for power spacecraft. A way to improve existing approaches to the development of space-based solar power plants and power satellites may be the use of mobile control methods in the development of an attitude and orbit control system. Such methods allow one to reduce power consumption for control operations. The goal of this paper is to study the features of mobile control and construct a methodology for the development of solar power satellites’ attitude and orbit control system (AOCS) using mobile control algorithms. The paper considers the features of mobile control algorithm synthesis for the attitude control and stabilization of solar power spacecraft (solar power plants and power satellites). Power spacecraft control tasks are classified, and the expediency of using mobile control methods is justified. An analysis is made for the stability problem that arises in controlling power spacecraft with flexible elements. The paper presents methodological recommendations on determining the AOCS design parameters for space-based solar power plants and power spacecraft for wireless satellite-to-satellite power transmission. This methodology may be used in power satellite development.
ОСНОВИ ТЕОРІЇ РЕСТАВРАЦІЙНИХ ПРОЦЕСІВ
Authors: Осипов С.
Published: November 2024

Вступ. Розробка та обґрунтування сучасних основ теорії реставраційних процесів є актуальним питанням, що дозволяє забезпечити подальший інноваційний розвиток та вдосконалення основ технології виконання та методології організаційно-технологічного проєктування процесів реставрації пам’яток архітектури.Проблематика. Це потребує встановлення нової системи логічних сутностей реставраційного процесу, фундаментальних положень, припущень та організаційно-технологічних обмежень. Ця система у власної сукупності висвітлює основну логіку теорії.Мета. Обґрунтувати основи теорії реставраційних процесів із власною системою правил і доказів, яка є адаптованою щодо особливих властивостей об’єкта та предмета дослідження — пам’яток архітектури та процесів їхньої реставрації.Матеріали й методи. Використано системні комплексні дослідження з урахуванням сучасних уявлень та принципів реставрації пам'яток архітектури, концептуальним підґрунтям є неодмінне забезпечення справжності об’єкта реставрації, його частини або елемента.Результати. Створено сукупність теоретичних положень, тверджень та логічних побудов, що описують основи теорії реставраційних процесів при реставрації пам’яток архітектури. Доведено, що центральним логічним елементом теорії реставраційних процесів є уявлення про єдиний спільно-одночасний процес перетворення матеріальних елементів та об’єкта реставрації, які розглядаються як єдиний предмет праці реставраційного процесу.Висновки. Створення основ теорії реставраційних процесів, що здійснюються під час реставрації пам’яток архітектури, дозволило упорядкувати сучасні уявлення, принципи і підходи щодо технології та організації реставрації у відкриту, внутрішньо диференційовану та цілісну систему знань, в якій процес реставрації розглядається як певний порядок виконання комплексу реставраційних процесів різної складності, сутність, структура та встановлені комбінації якого визначаються системними властивостями об’єкта реставрації, умовами виконання реставраційних процесів та існуючими організаційно-технологічними обмеженнями.
Multidimensional and Longitudinal Impact of a Genetic Diagnosis for Critically Ill Infants
Authors: Wojcik Monica H. , del Rosario Maya C. , Feldman Henry A. , Smith Hadley Stevens , Holm Ingrid A.
Published: November 2024

BACKGROUND AND OBJECTIVES

Many genetic conditions present in the NICU, where a diagnostic evaluation is pursued. However, understanding of the impact of a genetic diagnosis on clinical outcomes and health-related quality of life for these infants remains incomplete. We therefore evaluated parent-reported outcomes complemented by clinical outcomes measures over one year for a cohort of infants in the NICU undergoing genetic evaluation.

METHODS

Prospective cohort study evaluating outcomes after genetics consultation in a level IV NICU via parent report and electronic medical record review. Eligible infants were genetically undiagnosed at enrollment. Parent surveys were administered at baseline and 3, 6, and 12 months following enrollment and assessed genetic testing utility as well as parent-reported infant health-related quality of life using the Infant Toddler Quality of Life Questionnaire.

RESULTS

A total of 110 infant–parent pairs were enrolled. Infants had a median age at enrollment of 15 days (interquartile range 8–37.75). At baseline, 74% (81/110) of parents endorsed high importance of finding a genetic diagnosis, but perceived importance significantly decreased over time. Over the study period, 38 infants received a molecular diagnosis per parent report, although this was discordant with electronic medical record review. Identification of a diagnosis did not significantly impact health-related quality of life across most domains, which was lower overall than population norms.

CONCLUSIONS

A genetic diagnosis is highly desired by parents in the NICU, though waning interest over time for undiagnosed families may reflect parental emotional adaptation and acceptance. Additional supports are needed to improve perceived quality of life.
Resiliência na interação entre fatores de risco e de proteção no envelhecimento
Authors: Da Silva Júnior Edivan Gonçalves , Eulálio Maria do Carmo
Published: November 2024

Objetivou-se avaliar a relação da resiliência e variáveis demográficas (idade, sexo, estado civil, religiosidade), com fatores de risco (eventos de vida, estresse, depressão) e de proteção (apoio social, esperança) no envelhecimento. Foram utilizados os seguintes instrumentos: Questionário Sociodemográfico, Inventário de Eventos Estressantes, Escala de Depressão Geriátrica, Escala de Resiliência, Escala de Esperança de Herth, Inventário de Rede de Suporte Social. Participaram 508 idosos com média de 71,16 anos. Os índices de resiliência, de esperança e de apoio social foram satisfatórios. Destacaram-se os eventos que afetam o bem-estar pessoal e 23,6% dos idosos apresentaram sintomatologia depressiva. A idade se correlacionou negativamente com a resiliência e a esperança. O teste de regressão linear múltipla resultou em um modelo no qual 22% do índice de resiliência foram explicados pelas variáveis esperança e depressão. Idosos mais longevos indicaram aumento de agravos à saúde mental; assim, práticas de promoção da resiliência devem ser privilegiadas com esse grupo.
Bunt przeciw uprzedmiotowianiu Teodycea, sny i niesamowitość w literaturze obozowej
Authors: Papp-Zakor Ilka
Published: November 2024

Istnienie obozów nazistowskich i sowieckich było skandaliczną niesprawiedliwością, i praktycznie każdy tekst literacki napisany na ich temat traktuje je jako taką. Jednym z elementów rozważań nad tematyką obozów jest pytanie o to, czy można się spodziewać zadośćuczynienia po wydarzeniu, podczas którego było się upokorzonym, wręcz odczłowieczonym, żyło się w każdym momencie w zagrożeniu egzystencjalnym, często tracą całą rodzinę, zdrowie fizyczne i psychiczne? I czy martwi mogą liczyć na jakiekolwiek zadośćuczynienie? Niektóre teksty wydają się twierdzić, że do pewnego stopnia tak.

Najbardziej tradycyjnym sposobem na udowodnienie, że wydarzeniom wojennym jednak nie udało się do końca zniszczyć porządku świata, jest teodycea, stosowana mniej lub bardziej otwarcie zwłaszcza w literaturze mitotwórczej, a także jej odwrotność, otwarta negacja jakiegokolwiek porządku metafizycznego, jakiejkolwiek opatrzności, będąca gestem zadośćuczynienia, przywracającym narratorowi aktywną podmiotowość poprzez akt buntu.

Literatura obozowa obfituje jednak i w motywy symbolizujące odwrócenie porządku świata w mniej dosłowny sposób. Tak w tekstach o lagrach, jak i w tych o łagrach spotykamy się dość często z obrazami snów, nieraz spełnionych. Z badań historio-psychologicznych wiemy, że wspólne omawianie sennych widzeń w obozach było czynnością istotną z wielu powodów: między innymi dlatego, że wróżenie łudziło pewnym, choć raczej ograniczonym, odzyskaniem kontroli nad swoim własnym losem. Ale wspomnienia powstałe już po wyzwoleniu, napisane skądinąd w duchu realistycznym, też podchodzą z powagą do wróżebnej mocy snów, powtarzając gest – w momencie pisania – już anachroniczny, którego funkcja nie ulega jednak zmianie, ponieważ jest działaniem dążącym do odzyskania kontroli.

Drugim często spotykanym narzędziem stosowanym (między innymi) w wyżej wymienionym celu jest niesamowitość (w znaczeniu freudowskim). I ta może mieć różne odmiany, od reprezentacji duchów poprzez miejsca naznaczone niesamowitością aż do języka, na pozór niewinnego, lecz sygnalizującego między wierszami rzeczywistość zbrodni. Niesamowitość można rozumieć, w zależności od tekstu, jako oznakę ciągłego istnienia ofiar (więc jako namiastkę, alternatywę życia), lub też jako zemstę przeszłości nad przyszłością (tj. naszą teraźniejszością), będącą warunkiem wstępnym do ewentualnego katharsis. Paranoiczne czytanie, paranoiczne odczytywanie języka również są gestami nakierowanymi na odzyskanie kontroli.

Postpamięć, mimo wszystko patrząca na literaturę tworzoną przez ofiary bezpośrednie z pewnym dystansem, podchodzi do powyższych motywów w sposób kreatywny, analityczny lub filozoficzny, nieraz kontestując je, czasem wręcz z ironią, aby otwierać nowe perspektywy związane z tematyką obozową.
Review of SAR based deformation monitoring case studies related to the development of Hungarian Ground Motion Service (HGMS)
Authors: Magyar Bálint
Published: November 2024

In this paper I presented case studies related to the development of the Sentinel-1 based Hungarian Ground Motion Service (HGMS). I discussed the applied materials and approaches. Regarding this, I demonstrated the capability of conducting AZPO, 2.5D DInSAR, PSI and SBAS analyses as well. According to such case studies, I investigated the co-seismic field of the 2020 Petrinja and the 2023 Eastern-Turkey Earthquake Sequences. Next, the mining and/or heavy industry related examples in neighboring countries are investigated. Besides, I also highlighted application of the technology over red-mud reservoirs related to the Neszmély case-study. Later, I presented the ESA funded utilization and integration of the derived results to the kinematic height reference scoped INGRIM project.
Optimization of Sentiment Analysis for Indonesian Presidential Election using Naïve Bayes and Particle Swarm Optimization
Authors: Hayatin Nur , Marthasari Gita Indah , Nuarini Lia
Published: November 2024

Twitter can be used to analyze sentiment to get public opinion about public figures to find a trend in positive or negative responses, especially to analyze sentiments related to presidential candidates in the 2019 election in Indonesia. Naïve Bayes (NB) can be used to classify tweet feed into polarity class negative or positive, but it still has low accuracy. Therefore, this study optimizes the Naïve Bayes algorithm with Particle Swarm Optimization (NB-PSO) to classify opinions from twitter feeds to get a good accuracy of public figures sentiment analysis. PSO used to select features to find optimization values to improve the accuracy of Naïve Bayes. There are four steps to optimize NB using PSO, i.e., initializing the population (swarm), calculate the accuracy value that matched with selected features, selected the best accuracy of classification, and updating position and velocity. From this study, the group of tweets was obtained based on the positive and negative sentiments from the community towards two Indonesia presidential candidates in 2019. The NB-PSO test shows the accuracy result of 90.74%. The result of accuracy increases by 4.12% of the NB algorithm. In conclusion, the inclusion of the Particle Swarm Optimization algorithm for Naïve Bayes classification algorithm gives a significant accuracy, especially for sentiment analysis cases.
Convolutional-free Malware Image Classification using Self-attention Mechanisms
Authors: Dong Huiyao
Published: November 2024

Malware analysis is a critical aspect of cybersecurity, aiming to identify and differentiate malicious software from benign programmes to protect computer systems from security threats. Despite advancements in cybersecurity measures, malware continues to pose significant risks in cyberspace, necessitating accurate and rapid analysis methods. This paper introduces an innovative approach to malware classification using image analysis, involving three key phases: converting operation codes into RGB image data, employing a Generative Adversarial Network (GAN) for synthetic oversampling, and utilising a simplified Vision Transformer (ViT)-based classifier for image analysis. The method enhances feature richness and explainability through visual imagery data and addresses imbalanced classification using GAN-based oversampling techniques. The proposed framework combines the strengths of convolutional autoencoders, hybrid classifiers, and adapted ViT models to achieve a balance between accuracy and computational efficiency. As shown in the experiments, our convolutional-free approach possesses excellent accuracy and precision compared with convolutional models and outperforms CNN models on two datasets, thanks to the multi-head attention mechanism. On the Big2015 dataset, our model outperforms other CNN models with an accuracy of 0.8369 and an AUC of 0.9791. Specifically, our model reaches an accuracy of 0.9697 and an F1 score of 0.9702 on MALIMG, which is extraordinary.
Enhancing Video Anomaly Detection with Improved UNET and Cascade Sliding Window Technique
Authors: R. Krishnan Sreedevi , Amudha P.
Published: November 2024

Computer vision video anomaly detection still needs to be improved, especially when identifying images with unusual motions or objects. Current approaches mainly concentrate on reconstruction and prediction methods, and unsupervised video anomaly detection faces difficulties because there are not enough tagged abnormalities, which reduces accuracy. This paper presents a novel framework called the Improved UNET (I-UNET), designed to counteract overfitting by addressing the need for complex models that can extract subtle information from video anomalies. Video frame noise can be eliminated by preprocessing the frames with a Weiner filter. Moreover, the system uses Convolution Long Short-Term Memory (ConvLSTM) layers to smoothly integrate temporal and spatial data into its encoder and decoder portions, improving the accuracy of anomaly identification. The Cascade Sliding Window Technique (CSWT) is used post-processing to identify anomalous frames and generate anomaly scores. Compared to baseline approaches, experimental results on the UCF, UCSDped1, and UCSDped2 datasets demonstrate notable performance gains, with 99% accuracy, 90.8% Area Under Curve (AUC), and 10.9% Equal Error Rate (EER). This study provides a robust and accurate framework for video anomaly detection with the highest accuracy rate.
Solving Paths Search Problems in Complex Graphs
Authors: Kudelia Victor
Published: November 2024

The construction of models of various systems is associated with the enumeration of the values of the parameters of the elements of the structure and taking into account all the characteristics of operation and interaction of components to find a certain set of solutions that determine the configuration of the system. Such tasks belong to enumeration type tasks and imply that some of the next solutions from this set are obtained from the previous solution in a certain order. It is known that any problem of the enumeration type is solved only by methods of exhaustive search, and other methods for their enumeration do not exist yet. The paper presents a new method of searching paths in a graph – the method of node-graph transformation. The proposed method, unlike the existing ones, allows one to search all directed simple paths in an oriented graph of arbitrary structure much faster. In the known graph search methods (Breadth First Search and Depth First Search), the object of the search is a path. The total number of such paths in the graph determines the size of the search space. The main idea of the node-graph transformation method is to significantly reduce the size of the search space by enlarging the search objects. The enlargement of enumeration objects is performed by clustering paths into combinatorial objects that concentrate some set of paths of the same length according to certain rules. These combinatorial objects are called node-graphs. A node-graph refers to center-peripheral combinatorial objects, and specific node-graph transformation operations have been developed to enumerate all paths in the graph, which allow finding new paths based on previous paths. The method can be used as a basic toolkit to reduce the dimensionality of the search space for solutions to NP-complete problems while maintaining the universality and accuracy of the full search.
Some characteristics of sediments in Cenozoic basins in Northern Vietnam: implication for Oligocene paleoclimate
Authors: Mai Thanh Tan , Dinh Van Thuan , Le Duc Luong , Tran Thi Thuy Van , Ngo Thi Dao
Published: November 2024

Oligocene sediments in northern Vietnam have been extensively studied in terms of geology, stratigraphy, paleogeography, formation environments, tectonics, etc. However, relatively little attention has been paid to the paleoclimate. The Oligocene climate interpreted herein is based on features recorded in sediments taken from the Dong Ho (Hoanh Bo basin), Na Duong (Na Duong basin), and Co Phuc (Red River Trough) formations. These sediments were analyzed using thin-section microscopy, X-ray diffraction, and palynology with the Coexistence Approach. The sediments primarily consist of conglomerate, gritstone, sandstone, siltstone, claystone, and coal shale, deposited in continental environments and dated to the Oligocene based on palynomorph assemblages. The Oligocene paleoclimate is generally warm subtropical, with intermittent hot-humid or cold-dry periods and a slight influence of monsoons. An alternation of hot-humid and cold-dry climates was recorded in the Hoanh Bo basin. In the Red River Trough, the Oligocene climate exhibited a Mean Annual Temperature (MAT) of  9.3-22.2°C and a Mean Annual Precipitation (MAP) of 1122 to 1857 mm, based on the majority of palynological samples, indicating more continental, drier and colder conditions than present. In the Na Duong basin, a warm subtropical climate with a MAT of 9.3-21.7°C and MAP of 1122-1724 mm in the majority of samples was occasionally replaced by hot and humid subtropical periods; the variations in temperature and precipitation followed a similar pattern, suggesting an alternation between dry-cold and humid-hot phases.
Association between polymorphisms of IL33 and IL37 and atopic dermatitis
Authors: Svitich O. A. , Olisova O. Yu. , Potapova M. B. , Meremianina E. A. , Rasskazova N. D. , Belokopytova E. A. , Solodkova A. A. , Murzina A. A. , Semenova I. B. , Upatova A. G.
Published: November 2024

Atopic dermatitis (AD) is a chronic recurrent inflammatory disease accompanied by severe itching. One of the leading mechanisms underlying the development of AD is an imbalance of the Th1/Th2 cells immune response, which leads to an increased production of inflammatory mediators, including IL-1 family. The IL-1 family includes the recently discovered IL-33 and IL-37, and their role in the pathogenesis of AD has been actively studied. IL-33 functions as an alarmin that can induce IL-31 production, thereby leading to skin barrier impairment, pruritus and scratching. Having both immunomodulatory and immunosuppressive properties, IL-37 suppresses leukocyte infiltration of the affected skin and reduces the activity of proinflammatory cytokines. The aim of our study was to search for associations between gene polymorphisms of IL33, IL37 genes, and risk of AD. A total of 98 patients with moderate and severe AD were included in the study. The control group included 72 healthy volunteers. Polymorphic markers were determined in peripheral blood. After extraction of total RNA, polymorphic markers rs7019575 in the IL33 gene, rs3811046 and rs3811047 in the IL37 gene were analyzed using RT-PCR. There was no statistically significant difference in allele frequency and genotype distribution of rs7019575 (IL33) and rs3811047 (IL37). Studying the rs3811046 polymorphic marker in the IL37 gene showed that the risk of AD was almost 2 times lower for the G allele carriers and more than 2-fold higher for TT homozygous carriers. The haplotype analysis revealed that the GTAA and TTGG haplotypes of IL37 were associated with AD, thus increasing the risk of AD development by 2 and 10 times, respectively. In conclusion, SNP markers identified in this study can be used to predict the risk of AD development in the subjects with a positive family history of atopic diseases.
Dynamics of humoral immunity during natural SARS-CoV-2 infection and/or after vaccination with the ‘Sputnik V’ vaccine
Authors: Ivanov A. V. , Uvarova M. A. , Frolov K. B. , Semenova E. V.
Published: November 2024

Comprehensive analysis of adaptive immune response to SARS-CoV-2 is critical for epidemiological monitoring, as well as for tracking immune response stages and vaccination strategies. Understanding the differences between immunity formed after COVID-19 infection and vaccine-induced immunity is a specific task within this problem. Moreover, the obvious task is to assess the effect of repeated antigenic stimulation on immunological defense against SARS-CoV-2. The aim of present study was a comparative analysis of humoral immunity (anti-SARS-CoV-2 IgA and IgG) developing after natural infection with SARS-CoV-2 and/or after vaccination with anti-COVID vaccine “Sputnik V”. The study involved 36 volunteers. 21 of them had COVID-19 and were vaccinated 8-10 months later (group 1). In 15 primarily vaccinated persons, previous SARS-CoV-2 infection was excluded by means of regular PCR screening and serological testing (group 2). Results: Intensity of humoral immune response to the primary natural SARS-CoV-2 infection and similar indexes of antiviral adaptive immunity after vaccination with “Sputnik V” vaccine were similar in both groups. However, both maximal values of anti-SARS-CoV-2 IgA and IgG and the rates of post-vaccination humoral immune response differed significantly between the persons who have previously had COVID-19 and those who have not previously been infected with SARS-CoV-2. We’ve got statistically significant differences between two groups of participants using Student’s t test comparing the average maximum IgA levels after vaccination (p < 0.05). For IgG levels, these differences are less pronounced. In the first group, the average maximal values of specific IgA and IgG levels after natural infection with SARS-CoV-2 and after subsequent vaccination differed by more than 2 times. The time intervals for reaching maximal antibody levels after vaccination proved to be significantly shorter in the subjects who had a story of COVID-19, than in persons who did not report a clinical COVID-19 infection. Concerning the terms of arising IgG antibody response after vaccination versus cases of COVID-19 in the first group, we obtained a statistically significant difference by the Student’s t-test (p < 0.05). Hence, the persons with a previous natural COVID-19 infection develop a faster, stronger and more durable response to the “Sputnik V” vaccine than the subjects who had no such infection in their history
Expansion of the γδT cell population in peripheral blood: a response of immune system to the damage of gastrointestinal mucous membranes in older age groups
Authors: Stenina M. A. , Gromova T. V. , Grechenko V. V. , Gankovskaya L. V.
Published: November 2024

γδT cells are unique lymphocytes that take an intermediate position between the cells of innate and adaptive immunity. Even at the stage of differentiation in the thymus, they acquire the status of effectors with cytotoxic activity and become powerful cytokine producers. The antigen-recognizing receptor of γδT cells formed by γ and δ chains and is assigned an important role in activation of these cells in tissues: it recognizes infected and tumor cells by the presence of intracellular stress molecules. γδT cells are found in the blood and mucous membranes. Today, researchers’ attention is focused on two subpopulations of γδT cells: γδ1 and γδ2. The first is abundantly represented in the mucous membranes, the second forms the bulk (90%) of circulating γδT cells. The aim of this study was to assess the level of circulating γδT cells in patients of older age groups with proven pathologies affecting mucous surfaces at various segments of the digestive tract. We have recruited older patients from the Russian Gerontological Research and Clinical Center aged 60 to 90 years. The main group (n = 28) included patients with lesions of the gastric mucosa and duodenum with erosive ulcerative foci. The age-matched comparison group (n = 33) consisted of patients without gastrointestinal manifestations and did not have indications for gastroduodenoscopy. A separate group (n = 35) included patients with varying degrees of colon dysbiosis. The number of γδT cells in the blood was determined by two-color flow cytofluorometry using monoclonal antibodies. Presence of erosive and ulcerative foci in the mucous membranes of the stomach and duodenum was associated with increased numbers of circulating γδT cells population. An impaired function of intestinal barrier is considered a detrimental consequence of colon dysbiosis. Among patients with severe dysbiosis (3rd degree), the proportion of patients with a high content of γδT cells was significantly higher than among patients with the 1st (milder) degree of dysbiosis. Hence, the circulating population of γδT cells in the patients of the older age group responds by increased numbers to the damage (severity of damage) of the mucous membrane observed at different segments of digestive tract. The nonspecific nature of this response is obvious. Nevertheless, the expansion of this population in the circulating blood may be a sign of particular pathological process thus requiring further advanced diagnosis.
Functional status of blood neutrophils in congenital defects of antibody production
Authors: Novikova I. A. , Prokopovich S. S.
Published: November 2024

We evaluated some functional indices of neutrophils in 100 adult patients with a verified diagnosis of primary antibody production deficiency (44 patients with common variable immunodeficiency – CVID, and 56 patients with selective IgA deficiency – SigAD). The diagnosis was made according to the criteria of the Pan-American Group for Immunodeficiency and European Society for Immunodeficiency. The criteria for diagnosis were based on clinical data, medical history and results of laboratory tests. All patients with CVID received regular immunoglobulin replacement therapy, and the SIgAD patients received symptomatic treatment on demand. The examination was performed beyond the infectious episodes, inflammatory events or exacerbation of chronic disorders upon admission for planned hospitalisation, before any therapeutic and diagnostic procedures. In addition to standard clinical and laboratory examination appointed for the mentioned diseases, we assessed fnctional status of neutrophils: superoxide-anion radical production, NETosis, phagocytosis and apoptosis. Taking into account clinical manifestations, the patients with CVID were divided into 6 clinical subgroups: without CVID-related complications (13.6%); with infectious complications, i.e., bronchiectatic disease (15.9%), autoimmune syndromes (22.7%), polyclonal lymphoid infiltration (13.6%), enteropathic syndrome (34.1%), and malignant neoplasms (9.1%). Four phenotypes were identified in the patients with SIgAD: absence of SIgAD-related complications (28.6%); autoimmune syndrome (16.1%), non-malignant lymphoproliferation (3.6%) and enteropathy (28.6%). Higher incidence of non-infectious complications (autoimmune syndrome, non-malignant lymphoproliferation, enteropathies) was found in СVID compared to SIgAD patients (χ2 = 10.27; p = 0.001). Patients from the both groups showed changes in neutrophil reactivity compared to control values expressing higher basal generation of superoxide radicals (p < 0.001), NETosis activity (p = 0.005) and apoptosis (p < 0.001) with decreased phagocytic function (p < 0.001) and lower reserve for reactive oxygen species formation (p < 0.001). The maximal degree of changes in phagocytosis and superoxide-producing activity was observed in СVID; altered NETosis was revealed in SIgAD. The development of non-infectious complications was accompanied by a significant increase in stimulated NETosis indexes, thus suggesting a promising index in order to assess stability of clinical course and to predict development of complications in congenital defects of antibody production.
The effect of inflammation on the course of experimental aseptic necrosis of femoral head
Authors: Shabaldin N. A. , Sinitskaya A. V. , Bogdanov L. A. , Shabaldin A. V.
Published: November 2024

Aseptic necrosis of the femoral head is a staged process in which osteodestruction is replaced by the bone repair. The outcome of this disease may be characterized by severe discongruence of the hip joint area, disability of the patient. Recently, the research interest is drawn to molecular and cellular mechanisms of bone homeostasis disorders and ways of its correction. A number of studies have demonstrated the role of nonspecific inflammation in pathogenesis of aseptic necrosis. However, a more detailed study of dynamic changes in the activity of osteogenesis signaling pathways is required. The aim of this study was to assess the role of molecular patterns of inflammation and osteogenesis during aseptic necrosis of femoral head in experimental model. Surgical induction of aseptic necrosis of the femoral head was performed in 16 rats, which were removed biweekly from experiment (by 4 animals), for 8 weeks. The expression of genes encoding proteins involved in osteogenesis regulation was studied by qPCR with reverse transcription. Concentration of VCAM1, MMP9 proteins was assessed by immunoblotting. The results of our study demonstrated heterogenous dynamics of changes in molecular and cellular disorders associated with bone homeostasis regulation in pathogenesis of aseptic necrosis. For the first two weeks after surgical procedure, the expression of HIF1α and TNFα genes, as well as the concentration of MMP9 and VCAM1 proteins, were determined as predictor factors. After 1 month, VCAM1 protein concentration and TNFα gene expression acted as protector factors, whereas IL6 gene and MMP9 protein were considered predictive factors. After 6 weeks, the development of aseptic necrosis was promoted by expression of the IL4 gene, and after 8 weeks, by IL6 gene. Thus, an important role in regulation of osteoresorption belongs to nonspecific inflammation, which can be triggered by acute tissue hypoxia. A significant effect of the inflammation process persists up to 8 weeks after induction of avascular necrosis of femoral head. Pathogenesis of bone destruction is associated not only with an increased activity of osteoclastogenesis, but also with a decreased intensity of osteoblastogenesis. In general, the molecular and cellular pattern of bone homeostasis disorders varies depending on the stage of aseptic necrosis.
Peruvian organic agro-exports, climate change and food security
Authors: Coayla Edelina , Bedón Ysabel
Published: November 2024

Abstract Although organic export agriculture is affected by climate change, it is an essential climate adaptation mechanism. The objective of this article is to examine the link between climate change, organic Peruvian agro-exports, and food security. Using Pearson's correlation and multiple regression methods, the study found that climate change as measured by air and seawater temperatures was related to Peruvian organic agro-exports in the period 2000-2022. There was also a strong association between organic agro-exports and food security both in Peru and globally. It is concluded that the prevalence of global undernourishment is directly affected by air and sea surface temperatures and that this phenomenon is inversely affected by Peruvian organic agro-exports; i.e., higher organic agro-exports increase food security. It is recommended that policymakers promote organic agro-exports as a climate change adaptation strategy in support of healthier diets for populations, global food security, and climate resilience.
A relação entre a estrutura fundiária e o produto no Brasil
Authors: Oliveira Pedro Rodrigues , Almeida Alexandre Nunes de , Bragagnolo Cassiano , Faria Weslem Rodrigues
Published: November 2024

Resumo Este estudo busca analisar a relação entre a distribuição da posse da terra e os níveis de produto e produto agropecuário no Brasil e em suas cinco regiões geográficas. Para isso, construiu-se um índice de Gini da posse da terra a partir dos dados dos Censos Agropecuários de 2006 e 2017. Posteriormente, foram estimados modelos de Mínimos Quadrados em Dois Estágios com Variável Instrumental (MQ2E-VI) controlando para efeitos fixos, para estabelecer a relação entre este índice e os níveis de produto dos municípios brasileiros. Os resultados indicam que, no Brasil e nas regiões Nordeste, Centro-Oeste e Sul, o índice de Gini se relaciona de maneira positiva com as variáveis de produto. Na região Centro-Oeste, este índice mostra uma resposta mais significativa sobre o produto em comparação às outras regiões analisadas. Compreender a relação entre a distribuição da posse da terra e os níveis de produto é essencial para o debate sobre a estrutura fundiária no Brasil, um tema complexo. Os resultados também podem contribuir para a formulação de políticas públicas que visem a estimular o produto agropecuário no Brasil, considerando as especificidades regionais.
Páginas proibidas: censura de livros no Brasil
Authors: Viana Renata Teodoro , Muriel-Torrado Enrique , Prado Jorge Moisés Kroll do
Published: November 2024

Resumo: A censura de livros acompanha a história da humanidade desde a invenção da escrita e não está limitada a países onde imperam regimes totalitários ou fundamentalistas. No Brasil está presente desde o período colonial e comumente as pesquisas sobre o assunto abordam a censura em períodos de regimes totalitários. Essa pesquisa partiu da necessidade de investigar de que formas a censura se apresenta e suas motivações, bem como trazer à tona a percepção das pessoas em geral sobre a censura de livros no Brasil. O objetivo deste estudo é identificar os elementos que constituem os atos de censura de livros no Brasil, a partir de motivações, obras e autorias. Especificamente buscou-se identificar os atos/eventos/episódios de censura; identificar os títulos e/ou autores de livros mais censurados; e analisar as razões por trás da censura desses títulos e/ou autores, investigando a que tipo de questões estão relacionadas. Trata-se de uma pesquisa descritiva, bibliográfica e de abordagem quali-quantitativa cujo instrumento foi um questionário online de natureza mista e as respostas submetidas à análise de conteúdo. Os resultados apontam a ocorrência de censura de livros no país, em especial no âmbito da biblioteca escolar, sendo perpetrada principalmente por autoridades da instituição e por pais/responsáveis, em sua maioria entre 2022 e 2023. A motivação central identificada reside na consideração de que a obra é inadequada para o público infantil e/ou adolescente. As razões subjacentes a esses atos de censura são moldadas por questões políticas, religiosas, morais e temáticas vinculadas a gênero e orientação sexual.
A musealização de um acervo apreendido: desafios infocomunicacionais na Coleção Oceanos Gêmeos do Museu Nacional da República em Brasília
Authors: Sousa Wilton Borges de , Britto Clovis Carvalho
Published: November 2024

Resumo: O artigo analisa alguns processos infocomunicacionais na musealização de coleções de arte apreendidas em operações policiais, tendo como estudo de caso a Coleção Oceanos Gêmeos. A coleção é composta por um conjunto de 183 obras de arte resultante de um processo judicial criminal, originário da Justiça Federal no Estado de São Paulo e atualmente sob guarda e responsabilidade do Museu Nacional da República, em Brasília. O recorte temporal compreende os anos de 2009 a 2022, datas da destinação da coleção ao museu e da finalização da pesquisa de campo. A metodologia da pesquisa é descritiva e exploratória com abordagem qualitativa, privilegiando o estudo de caso a partir da literatura científica sobre a temática e da documentação relativa à musealização da coleção. O artigo apresenta alguns dos desafios enfrentados pelos profissionais em museus depositários de coleções apreendidas em operações policiais e evidencia os processos infocomunicacionais realizados na coleção em análise. Nas considerações finais, aponta para a necessidade da elaboração de procedimentos judiciais para garantir as condições de salvaguarda dos acervos, sem ônus para as instituições, e da urgência de políticas públicas em torno de coleções apreendidas e musealizadas.
Pessoa arquivista e sua constituição identitária: influências na representatividade e nas atividades mediadoras da informação
Authors: Santos Raquel do Rosário , Sousa Ana Claudia Medeiros de
Published: November 2024

Resumo Esta pesquisa teve o objetivo de evidenciar se no ato mediador da informação realizado pelos(as) arquivistas transparece o viés da constituição identitária e da representatividade. De natureza qualitativa, de caráter descritivo, buscou realizar esta investigação junto aos profissionais vinculados à Associação dos Arquivistas da Bahia e à Associação dos Arquivistas da Paraíba. Sendo utilizado o questionário, como instrumento de coleta de dados e aplicado via e-mail. Como resultados foram interpretadas as percepções dos(as) arquivistas sobre sua conduta que se faz representativa, sendo que dos(as) 19 arquivistas nove participantes desta pesquisa afirmaram negativamente e dez indicaram que existe alguma experiência ou relato de usuários(as) que se sentiram representados(as) por algum de seus traços identitários (gênero, cor, raça, espaço geográfico). Conclui-se que o agir mediador, quando realizado de maneira consciente, é pautado em uma postura que não se desvincula da vida da pessoa arquivista, em que a sua interferência reflete os traços representativos no seu ato mediador, reconhecendo as similitudes e as diferenças dentro do coletivo que integra.
Post-informal caregiver’s perspectives and experiences of the support network: a systematic literature review and meta-synthesis
Authors: Afonso Catarina Inês Costa , Madeira Ana Cristina Spinola , Magalhães Susana Pinto Leite Vasconcelos Teixeira de
Published: November 2024

ABSTRACT Objective: To examine and synthesize the evidence of experiences and perspectives on the specific context of informal post-care and the existing support network. Method: This is a qualitative systematic review with metasynthesis, according to the framework of the JBI, carried out in the CINAHL, LILACS, MEDLINE, BVS and PsycINFO databases, with no time limit. The articles were evaluated using the JBI Qualitative Data Extraction Tool. A total of 1,236 articles was identified, of which 18 were selected and 7 were analyzed. The level of evidence found was moderate. Results: The experiences and perspectives of the informal post-caregiver reveal the need for support, namely: in personal development - attribution of meaning, in self-care perspectives and in identity reconstruction; in managing the impact of the legacy of caring - discontinuity of support in the trajectory of caring, financial vulnerability, and the impact on mental health; formal and informal resources for the future - projection of the future, structured services and family and community support. Conclusion: Post-caregivers’ perception of their support network is that their individual and interpersonal needs are not identified, and that formal and informal services are not articulated.
Power, Creativity, Innovation, and the Aesthetics of Existence in Contemporary Society and Organizations
Authors: Sant’Anna Anderson de Souza , Mezan Renato , Carvalho Matheus Cotta de
Published: November 2024

Abstract This article examines the potential discrepancies between the discourse surrounding an aesthetics of existence focused on innovation, personal empowerment, self-entrepreneurship, ownership, and creativity, and the persistent presence of deep-rooted contradictions within contemporary organizational mindsets and business models. Drawing on the works of Nietzsche, Foucault, and Deleuze, this analysis exposes these contradictions and their implications for understanding power dynamics within organizations. Despite the acknowledgement of the significance of human subjectivity, control mechanisms persist, undermining the transformative potential of these ideals. This persistence highlights the contradictions that exist between the proclaimed values of organizational discourse and the actual practices that perpetuate control and hinder genuine empowerment. Addressing these contradictions necessitates a comprehensive reassessment of organizational mindsets, management practices, and the broader social and economic context. By incorporating the insights of these authors, a more critical and nuanced understanding of power dynamics can be attained. This understanding can enable organizations to instigate meaningful change, thereby unleashing the true power of human subjectivity as a driving force for innovation and empowerment. This article underscores the urgency of confronting the contradictions between the rhetoric and reality within organizations. Integrating the insights of Nietzsche, Foucault, and Deleuze provides a framework for scholars and practitioners to engage in a critical reassessment of organizational mindsets, practices, and their far-reaching implications. This research calls for further exploration, prompting a deeper inquiry into the transformative potential of an aesthetics of existence and its profound impact on organizational practices and mindsets.
Poder, Criatividade, Inovação e a Estética da Existência na Sociedade e Organizações Contemporâneas
Authors: Sant’Anna Anderson de Souza , Mezan Renato , Carvalho Matheus Cotta de
Published: November 2024

Resumo Este artigo examina possíveis discrepâncias entre o discurso em torno de uma estética da existência focada na inovação, empoderamento pessoal, autoempreendedorismo, propriedade e criatividade, e a persistente presença de contradições profundas nas mentalidades organizacionais contemporâneas e nos modelos de negócios. Baseando-se em obras de Nietzsche, Foucault e Deleuze, esta análise expõe essas contradições e suas implicações para a compreensão das dinâmicas de poder dentro das organizações. Apesar do reconhecimento da importância da subjetividade humana, os mecanismos de controle persistem, minando o potencial transformador desses ideais. Essa persistência destaca as contradições que existem entre os valores proclamados no discurso organizacional e as práticas reais que perpetuam o controle e dificultam o empoderamento genuíno. Abordar essas contradições exige uma reavaliação abrangente das mentalidades organizacionais, práticas de gestão e do contexto social e econômico mais amplo. Ao incorporar os insights desses autores, pode-se alcançar uma compreensão mais crítica e nuançada das dinâmicas de poder. Essa compreensão pode capacitar as organizações a promover mudanças significativas, liberando assim o verdadeiro poder da subjetividade humana como uma força motriz para a inovação e o empoderamento. Este artigo destaca a urgência de confrontar as contradições entre a retórica e a realidade dentro das organizações. Integrar os insights de Nietzsche, Foucault e Deleuze fornece um framework para acadêmicos e praticantes se engajarem em uma reavaliação crítica das mentalidades e práticas organizacionais e suas implicações de longo alcance. Esta pesquisa chama por uma exploração mais aprofundada, provocando um inquérito mais profundo sobre o potencial transformador de uma estética da existência e seu impacto profundo nas práticas e mentalidades organizacionais.
Direito da criança à cidade: reconstrução teórica e aplicação em contextos urbanos diversificados
Authors: Silva Daniella Ramos da , Mello Sérgio Carvalho Benício de , Bastos Antonio Fagner da Silva
Published: November 2024

Resumo Conjectura-se que a maioria das crianças residirá em áreas urbanas na próxima década. Entretanto, as cidades não estão preparadas para atender às necessidades delas. Áreas urbanas estão predominantemente voltadas para o capital, priorizando o comércio e o trânsito automobilístico. Isso suscita questionamentos acerca da possibilidade do exercício pleno do direito à cidade e, consequentemente, da cidadania, mediada pela mobilidade urbana, momento em que os indivíduos interagem mais com o ambiente e estabelecem conexões interpessoais. Sob a ótica de uma epistemologia crítica, destaca-se a urgência de uma reconstrução teórica do direito à cidade, fundamentada na perspectiva da criança, por meio de um estudo de caso ampliado. Nesse contexto, analisou-se a experiência de crianças residentes na Ilha de Deus, em Recife. A pesquisa revelou que a efetivação da cidadania da criança por meio do direito à cidade, considerando-se um direito passível de reivindicação, não pode ser plenamente alcançada sem o suporte jurídico estatal. O direito das crianças à cidade requer respaldo de políticas públicas voltadas para o atendimento das demandas deste grupo etário. Da mesma forma, é fundamental evidenciar a apropriação do espaço urbano de acordo com as especificidades infantis, por meio dos affordances e da mobilidade urbana voltada para este público.
Práticas Corporais de Aventura na Graduação em Educação Física: estudo comparado UFSC-UFG
Authors: Inácio Humberto Luís de Deus , Bassani Jaison José
Published: November 2024

RESUMO Analisou-se a inserção das Práticas Corporais de Aventura na graduação em Educação Física da Universidade Federal de Santa Catarina e da Universidade Federal de Goiás, realizada durante o processo de reformulação curricular ocorrido nos últimos anos. A metodologia utilizada foi a de Educação Comparada. A Universidade Federal de Goiás criou uma disciplina introdutória, enquanto a Universidade Federal de Santa Catarina criou três – uma introdutória, uma específica para a licenciatura e outra optativa. Ambos os casos apresentam similaridades e distanciamentos na compreensão das novas diretrizes e na forma como isso se refletiu em seus Projetos Pedagógicos Curriculares, havendo forte influência dos territórios onde as instituições estão situadas. O artigo é concluído com a identificação dos avanços em cada instituição de ensino superior sobre esse conteúdo, desde a perspectiva da Educação Comparada.