bluuebunny/crossref_metadata_2025 huggingface dataset:
Alexandre entre dois mundos
Authors: Almeida da Silveira Michelle
Published: September 2023

O livro "Alexandre entre Dois Mundos" não pretende ser uma fonte de pesquisa, para isso, indico as fontes que utilizei. No entanto, ele se apresenta como um guia para auxiliar professores a explorar esse rico conteúdo em sala de aula. Além disso, ele é uma ferramenta para transportar meus alunos para a extraordinária vida de Alexandre, o Grande. um personagem cujo nascimento foi celebrado como algo mágico e grandioso. Ele nasceu em um momento de presságios e sinais, como o incêndio no templo da deusa Artêmises em Éfeso, que ecoava a importância de sua chegada. O livro explora a dualidade dos mundos que cercaram a vida de Alexandre: o Ocidente e o Oriente, o mundo das cidades-estado helenas e o vasto império persa. Desde a infância, Alexandre demonstrou um notável apetite pelo conhecimento e uma habilidade excepcional para absorvê-lo. Ele foi educado pelo renomado filósofo Aristóteles e mergulhou em diversas disciplinas, desde matemática até filosofia e biologia. Seu amor pelas epopeias gregas, como a "Ilíada," moldou sua visão de mundo e sua busca por glória. O livro também nos apresenta a amizade de Alexandre com seus amigos de infância , incluindo Heféstion, que o acompanhou em suas jornadas e aventuras. A história destaca momentos marcantes, como a domesticação de Bucéfalo, o cavalo indomável que se tornou inseparável de Alexandre. Alexandre, o Grande, é retratado como um líder excepcional, alguém que buscava constantemente a excelência e que estava destinado a desempenhar um papel crucial na história. Sua busca por unir os mundos ocidental e oriental e suas conquistas monumentais são uma parte fundamental de sua jornada. Este livro nos convida a explorar a mente brilhante de Alexandre, sua paixão pela aprendizagem e sa determinação em superar desafios. É uma leitura cativante que nos inspira a compreender por que Alexandre é lembrado como um dos maiores líderes e conquistadores da história da humanidade.
Daño psíquico en víctimas de trata de personas de explotación sexual
Authors: López-Herrera Alejandra
Published: September 2023

En este estudio se planteó como objetivo el conocer y analizar el daño psíquico derivado de la victimización con fines de investigación judicial; esto, con el propósito de proponer un tratamiento y reparación del daño adecuado. Se revisó 9 casos de mujeres víctimas de trata de personas con fines de explotación sexual, quienes se encontraban en un refugio especializado en la trata de personas. Para la investigación, se realizó un análisis clínico basado en pruebas psicológicas y entrevistas a profundidad. Los resultados revelaron una alta prevalencia de lesiones psíquicas, incluyendo el Trastorno de Estrés Postraumático y secuelas psíquicas de importancia clínica; por ello, se recomendó el uso de la terapia cognitivo-conductual centrada en el trauma, así como la terapia de desensibilización y reprocesamiento del movimiento ocular. Además, se resaltó la importancia de brindar medidas de asistencia integral y un seguimiento adecuado a las víctimas y se enfatizó en la relevancia de los dictámenes psicológicos para llevar a cabo la reparación del daño en consideración de las implicaciones del daño psíquico a corto, mediano y largo plazo. De esta manera, se busca que la reparación no se limite a un número fijo de sesiones terapéuticas, sino que se contemplen todas las implicaciones que las secuelas psíquicas provocan en las víctimas.
Creación del Comité Interinstitucional para atender el desplazamiento forzado interno en Michoacán, México
Authors: Zambrano-Vázquez Diana Pamela
Published: September 2023

La movilidad humana es una actividad palpable actualmente; sin embargo, aunque este derecho humano se encuentra reconocido en diversos instrumentos, su exigibilidad no ha dejado de ser un reto. Es por ello que se debe mostrar lo que ha ocurrido en Michoacán (México), con el objetivo de atender la situación de las personas en desplazamiento forzado interno; para esto, se comparte el desarrollo de una metodología que apunta a la creación de una ley que atienda tal situación. Asimismo, se considera que el trabajo es relevante dado que se trata de una suma de esfuerzos por parte de varios sectores cuyo fin de erradicar la ausencia de un marco normativo que haga alusión al desplazamiento forzado en Michoacán; para ello, en abril de 2022, se publicó el decreto para crear el Comité Interinstitucional para la Atención del Desplazamiento Forzado; posteriormente, se realizaron sesiones en las que se contó con la presencia del Alto Comisionado de las Naciones Unidas para los Refugiados, Observatorios de Seguridad Humana, la Unidad de Política Migratoria, Médicos Sin Fronteras, entre otros actores. El resultado de este intercambio de ideas generado en cada encuentro ha fortalecido la iniciativa que el gobernador del Estado presentará al Poder Legislativo local, quien deberá dar vida jurídica a un cuerpo que haga referencia al trato para las personas en condición de desplazamiento forzado interno en Michoacán.
La intervención social de las víctimas de trata de personas en Costa Rica, 2018-2022
Authors: Paniagua-Bonilla Alejandra , Villalobos-Torres Gabriela
Published: September 2023

Este artículo presenta los resultados parciales de la investigación denominada «Proceso de reintegración de las víctimas de trata de personas en Costa Rica». Un estudio exploratorio que interroga acerca de la intervención social realizada con las víctimas de este delito y su proceso de reintegración, en el marco de la ejecución de la Estrategia de Atención Integral y de movilización de recursos de apoyo para las víctimas-sobrevivientes de la trata de personas y sus dependientes: integración, reintegración, repatriación, retorno voluntario y reasentamiento (en adelante, Estrategia de Atención Social) durante el periodo 2018-2021. Es innegable que las características y las dinámicas del fenómeno demandan acciones institucionales en todas las etapas del ciclo de la trata (captación, transporte, explotación, detección-rescate o fuga y reintegración). Sin embargo, este artículo se focaliza en la intervención con las sobrevivientes acreditadas por la CONATT (Coalición Nacional Contra el Tráfico Ilícito de Migrantes y la Trata de Personas) en la fase de reintegración. Para ello, caracteriza la intervención social en el marco de dicha estrategia, recuperando el proceso de evolución del componente de atención de la trata en el país. A partir de esta ruta, el artículo concluye que es importante para las víctimas contar con acceso permanente a una plataforma de servicios y recursos estatales durante la fase de reintegración.
Pediatric Cutaneous Gamma-delta T-cell Neoplasm and Mimics: Not Always Aggressive
Authors: Cheng Jinjun , Toner Keri , Habeshian Kaiane , Cardis Michael , Bollard Catherine , Wistinghausen Birte , Kirkorian Anna
Published: September 2023

Pediatric cutaneous T-cell lymphoma with γδ immunophenotype is extremely
rare. Only a few cases of γδ T-cell neoplasm have been reported in the
literature and therefore little is known whether γδ T-cell neoplasms in
children are distinct from their adult counterparts with respect to the
clinicopathological presentation, behavior and prognosis. In this study,
we demonstrate three unique cases with increased γδ T-cells in malignant
and non-malignant skin conditions of children. All cases showed an
indolent clinical course. Full integration of clinical presentation,
morphology, immunophenotype, and genetics supports the correct diagnosis
and guides the treatment.
Nukleáris medicina a prosztatarák diagnosztikájában és kezelésében (teranosztika)
Authors: Bús Katalin , Nádasdy-Horváth Domonkos , Györke Tamás
Published: September 2023

Az elmúlt években, évtizedekben a nukleáris medicina hatalmas fejlődésen ment át, számos radiofarmakológiai fejlesztés született, és a hibrid berendezésekkel (PET/CT, PET/MR, SPECT/ CT) végzett vizsgálatok is könnyebben elérhetővé váltak a klinikai gyakorlatban. A nukleáris onkológia egyik legjobban kutatott területe a prosztatarák volt, aminek köszönhetően több új radiofarmakon került forgalomba mind diagnosztikus, mind terápiás célra, ezeket Magyarországon is bevezették, illetve elérhető közelségbe kerültek. A szerzők azokat a – prosztatarák-diagnosztikában és -terápiában használt – nukleáris medicinai módszereket foglalták össze, amelyek a klinikai gyakorlatban a legfontosabbak.
A prosztatarák hormonterápiája (elsődleges hormonkezelés)
Authors: Horváth András , Szalontai János , Riesz Péter , Szűcs Miklós , Nyirády Péter
Published: September 2023

Az előrehaladott és metasztatikus prosztatarák kezelésének alapja az androgéndeprivációs terápia, amely során a here androgén szekréciójának különböző módon történő elnyomását végezzük. Leggyakrabban használt formája a kémiai kasztráció LHRH analóg/antagonista készítményekkel. Lokálisan előrehaladott prosztatarák esetén a hormonterápia (ADT) kombinációja javasolt helyi kezeléssel (radioterápia vagy radikális prostatectomia) a túlélés javítása érdekében. Radikális műtét után igazolt nyirokcsomó-pozitivitás esetén a korai adjuváns hormonterápia javítja a daganatspecifikus túlélést, amelynek kiegészítése a prosztataágy sugárkezelésével további előnyt jelenthet. Metasztatikus prosztatarák esetén is a kombinációs kezelések jelentik a standard elsővonalbeli terápiát, elsősorban ADT és ARPI (abirateron, apalutamid, enzalutamid) együttes adásával.
A prosztatarák diagnosztikája
Authors: Kalina Ildikó
Published: September 2023

A Magyarországon működő 1,5 T és 3 T mágneses térerősségű MR-készülékek alkalmasak a prosztata célzott MR-vizsgálatára, így lehetőséget nyújtanak a prosztata komplex, multiparametrikus MR-képalkotására és a PI-RADS alkalmazására. A PIRADS azzal a céllal jött létre, hogy egyszerűsített és standard módszert kínáljon a prosztata-MR leletezésére, megkönnyítse a radiológus és a klinikus közötti interdiszciplináris kommunikációt.
IL-6 Trans-Signaling Is Increased in Diabetes, Impacted by Glucolipotoxicity, and Associated With Liver Stiffness and Fibrosis in Fatty Liver Disease
Authors: Gunes Aysim , Schmitt Clémence , Bilodeau Laurent , Huet Catherine , Belblidia Assia , Baldwin Cindy , Giard Jeanne-Marie , Biertho Laurent , Lafortune Annie , Couture Christian Yves , Cheung Angela , Nguyen Bich N. , Galun Eithan , Bémeur Chantal , Bilodeau Marc , Laplante Mathieu , Tang An , Faraj May , Estall Jennifer L.
Published: September 2023

Many people living with diabetes also have nonalcoholic fatty liver disease (NAFLD). Interleukin-6 (IL-6) is involved in both diseases, interacting with both membrane-bound (classical) and circulating (trans-signaling) soluble receptors. We investigated whether secretion of IL-6 trans-signaling coreceptors are altered in NAFLD by diabetes and whether this might associate with the severity of fatty liver disease. Secretion patterns were investigated with use of human hepatocyte, stellate, and monocyte cell lines. Associations with liver pathology were investigated in two patient cohorts: 1) biopsy-confirmed steatohepatitis and 2) class 3 obesity. We found that exposure of stellate cells to high glucose and palmitate increased IL-6 and soluble gp130 (sgp130) secretion. In line with this, plasma sgp130 in both patient cohorts positively correlated with HbA1c, and subjects with diabetes had higher circulating levels of IL-6 and trans-signaling coreceptors. Plasma sgp130 strongly correlated with liver stiffness and was significantly increased in subjects with F4 fibrosis stage. Monocyte activation was associated with reduced sIL-6R secretion. These data suggest that hyperglycemia and hyperlipidemia can directly impact IL-6 trans-signaling and that this may be linked to enhanced severity of NAFLD in patients with concomitant diabetes.

Article Highlights

IL-6 and its circulating coreceptor sgp130 are increased in people with fatty liver disease and steatohepatitis. High glucose and lipids stimulated IL-6 and sgp130 secretion from hepatic stellate cells. sgp130 levels correlated with HbA1c, and diabetes concurrent with steatohepatitis further increased circulating levels of all IL-6 trans-signaling mediators. Circulating sgp130 positively correlated with liver stiffness and hepatic fibrosis. Metabolic stress to liver associated with fatty liver disease might shift the balance of IL-6 classical versus trans-signaling, promoting liver fibrosis that is accelerated by diabetes.
Increased mortality after total hip prosthetic joint infection is mainly caused by the comorbidities rather than the infection itself
Authors: Persson Anders , Sköldenberg Olof , Mohaddes Maziar , Eisler Thomas , Gordon Max
Published: September 2023

Background and purpose: Periprosthetic joint infection (PJI) is a feared complication of arthroplasty surgery. There is controversy as to whether PJI also correlates with increased mortality. Our aim was to investigate in a nationwide cohort if PJI is an independent risk factor for dying.Patients and methods: We performed a retrospective cohort study based on data from the Swedish Hip Arthroplasty Register (SHAR). All patients with a revision THA performed between 1998 and 2017 were included. The outcome is mortality; exposure is PJI according to SHAR. The control group was study participants who underwent aseptic revision. Confounders were age, sex, diagnosis, and comorbidity according to the Elixhauser index. The outcome was analyzed with a Cox proportional hazards model.Results: 4,943 PJI revisions and 12,529 non-infected revisions were included in the analysis. The median follow-up time was 4.1 years. In the PJI group, 1,972 patients died and in the control group, 4,512. The incidence rate ratio was 1.19 (95% confidence interval [CI] 1.13–1.25), the crude hazard ratio (HR) 1.19 (CI 1.13–1.25), and the adjusted HR 1.05 (CI 0.99–1.12) for the exposed versus the unexposed group. The strongest confounder was comorbidity.Conclusion: The increased mortality risk after revision due to PJI is mainly caused by the comorbidity of the patient, rather than by the infection itself.
Conservative treatment of traumatic finger amputations using negative-pressure wound therapy
Authors: Mizutani Yasushi , Tamai Susumu , Nakamura Toshifumi , Hagiwara Yusuke , Takita Takehiko , Kawamura Kenji
Published: September 2023

Replantation is widely regarded as the first choice of treatment for finger amputations. However, if the fingertip of a traumatic finger amputation is missing after an injury, the following procedures are often performed to reconstruct this portion: flap surgery, stump surgery, or conservative treatment, including occlusive dressings. To our knowledge, no existing English literature reports using negative-pressure wound therapy (NPWT) to treat traumatic finger amputations.
We postulated that NPWT may be applied as a conservative treatment for traumatic finger amputations, promoting the growth of granulation tissue and achieving early epithelialization of the fingertips.
Among the case series of five patients, we included six injured fingers comprising two index, two middle, and two ring fingers. The fingertip of each traumatic finger amputation was either missing or highly crushed, making replantation impossible. To preserve finger length with conservative treatment, we adapted an NPWT device for finger amputations. It took an average of 22.7 days for the fingertips to epithelialize. Immediately after epithelialization, there was a slight decrease in sensory perception; however, all patients showed good recovery of sensory perception after 3 months. Range of motion remained unrestricted, with no reduction in grip strength. Patients were highly satisfied with their fingertip appearance. The regenerated nail exhibited slight deformation and shortening. No complications were observed.
Our novel study regarding this new conservative treatment and its outcomes revealed that healing was achieved in a relatively short period; therefore, NPWT may serve as a new conservative treatment option in the future.
Numerical investigation of the effect of oblique laser shock processing parameters on the residual stress and deformation characteristics of TC6 titanium alloy
Authors: Liu Yue , Li Sina , Wang Chongyang , Zhao Yanmin , Azad Fahad , Su Shichen
Published: September 2023

Oblique laser shock processing (OLSP) can provide a new solution for improving the mechanical properties of complex structural elements. In this paper, a spatial distribution model of OLSP shock wave pressure is established and validated to study the residual stress (RS) field and surface morphology of titanium alloy TC6 treated by OLSP using the finite element method. The effects of the incident angle, overlapping rate, and scanning pattern on the RS field and surface morphology were investigated. The OLSP results indicate that the overlapping rate should be at least 50%. The RS field and surface morphology obtained with the interval scanning pattern are more uniform compared to snake and spiral. With a 50% overlapping rate and interval scanning pattern, the surface roughness was found to be 0.16, and the surface residual compressive stress fluctuation amplitude was reduced by 40.07%. The results provide a theoretical basis for complex structures of LSP.
Gördes Havzası Akışlarının Modellenmesinde Era5-Land Verilerinin Performans Değerlendirmesi
Authors: EKİNCİ Destina Dilan , FISTIKOĞLU Okan
Published: September 2023

İklim değişikliğinin akarsu akımları üzerindeki etkilerinin hidrolojik modeller yardımıyla belirlenmesinde küresel atmosferik veri setlerinden sıklıkla faydalanılmaktadır. Sunulan çalışmada, Ege bölgesinde yer alan Gördes Havzası akımlarının hem küresel veri setleri hem de lokal istasyon verileri ile akışlarının modellenmesi ve bu model sonuçları dikkate alınarak performansın değerlendirmesi amaçlanmıştır. Küresel veri seti olarak ECMWF (European Centre for Medium-Range Weather Forecasts) tarafından sunulan 1959-2022 yılları arasında veri sağlayan ERA5 Land veri seti ve hidrolojik model olarak da abcd aylık yağış akış modeli kullanılmıştır. Model performansını değerlendirmek için Nash-Shutcliffe performans fonksiyonu seçilmiş olup optimum model parametrelerin tahmini için Parçacık Sürü Optimizasyonu Algoritması (PSO) kullanılmıştır. Çalışmada elde edilen bulgular ERA5 Land veri setinin Gördes Havzası’nın aylık akımlarının modellenmesinde havzanın hidrolojik özelliklerini başarılı bir şekilde yansıttığı ve bu veri setini kullanmanın modelleme çalışmalarında kolaylaştırıcı olacağı gösterilmiştir.
Role of Customer Satisfaction in Mediating the Effect of Product Quality and Service Quality on Customers’ Repurchase Intention of a Coffee Shop in Bali, Indonesia
Authors: Natalia Ni Komang Triska , Suparna Gede
Published: September 2023

Repurchasing intention is described as the behaviour of consumers in making repeated purchases of products that have been purchased previously. The positive feedback consumers receive after purchase creates repurchase intentions. Good repurchase intentions are influenced by many factors, i.e., product and service quality and customer satisfaction. This research was conducted to determine how product and service quality affect intention to make repeated purchases with customer satisfaction as mediation, with 119 respondents. Data was gathered using a questionnaire and analyzed using SmartPLS. Results imply that Product and Service quality has a significant positive effect on satisfaction and repurchase intentions. Customer satisfaction positively affects repurchasing intentions and mediates the relationship between product quality and service quality towards repurchase intentions.
ДРОБНОЕ ИНТЕГРОДИФФЕРЕНЦИРОВАНИЕ ДЕЛЬТА-ФУНКЦИИ ДИРАКА С ПОМОЩЬЮ d-ОПЕРАТОРА
Authors: Чуриков Виктор
Published: September 2023

Производится дифференцирование и интегрирование δ-функции Дирака с помощью d-оператора дробного интегро-дифференцирования. Для этого используется разложение в степенной ряд одного из возможных предельных представле-ний δ-функции, который поэлементно интегродифференциру-ется d-оператором.
ning exploration methods technology for environmental effect in the Caspian fields
Authors: Alekseev Andrei Germanovich , Radionova Elena Evgenievna , Bolgova Natalya Evgenievna
Published: September 2023

The method of performing exploration works allowing to obtain an environmental effect in the Caspian Sea fields is described in the article. The research area includes the Rakushechno-Latitudinal and Khvalynsko-Sarmatian zones. Deposits of these zones differ in a complex geological structure. When creating a model of deposits a set of data is used: high-precision 3D seismic surveys on the study area and the results of drilling wells. Such detail of seismic exploration works allows to obtain high-quality results that are due to the high density of reflection points over the area and to the maximum use of various dynamic parameters of reflected waves. The results of such surveys are used in the calculation of reserves, justification of work on additional exploration and subsequent operation. Based on the results of seismic surveys a quantitative forecast of reservoir properties was carried out due to the inversion. For implementation seismic data was processed while preserving the true amplitudes of the seismic signal. Drilling wells were also the main source of information when performing work on calculating reserves. The complex structure and heterogeneity conditions of reservoir properties in area and section, the presence of discontinuous violations led to the use of the described technology, which involves the assessment of reserves and their transfer to the industrial category without testing in the column and causing inflow to the surface. This is done by means of a comprehensive accelerated diagnostics of productive formations for the assessment of reserves of the industrial category. Such a diagnosis provides for the study of productive formations based on the analysis and generalization of accumulated material on core, GIS, GDIS, GDK-OPK and PVT studies, without conducting tests in wells. With the help of these studies the filtration-capacitance properties of rocks, the nature of fluid saturation, contact positions, static levels, reservoir and bottom-hole pressures and reservoir temperatures, as well as deep sampling are determined. The use of modern instruments such as MDT (reservoir Tester) makes it possible to obtain reliable deep samples of the reservoir fluid. The results of data interpretation are successfully approved when making reports on UVS reserves calculation.
Osmanlı Süreli Yayınlarında Batı Dünyasındaki Bilgi Kurumları ile İlgili Makaleler: Batılılaşma Bağlamında Bir Değerlendirme
Authors: SÜMBÜL Sinan
Published: September 2023

Amaç: Bu çalışmada, Osmanlı süreli yayınlarında neşredilen Batı ülkelerindeki bilgi kurumlarına dair makaleler incelenerek bunların, Osmanlı toplumunu bilgilendirici niteliklerinin ortaya konulması amaçlanmıştır. Kültür tarihinin önemli tanıklarından olan süreli yayınlar, yayınlandıkları dönemin hem siyasi hem de kültürel atmosferini yansıtması bakımından önemlidir. Süreli yayınlardan kültürel, toplumsal ve mesleki konulardaki gelişmeleri takip etmek mümkündür. Bu sebeple Osmanlı süreli yayınlarında Batı’daki bilgi kurumları hakkında yazılmış makaleleri odağa alan bir çalışma yapılmıştır.
Yöntem: Tarihsel yöntem ve belgesel tarama tekniği kullanılan çalışmada, konuyla ilgili 29 makaleye ulaşılmış ve bu makaleler incelenmiştir. İlgili makalelere Türkiye Diyanet Vakfı İslam Araştırmaları Merkezi (İSAM) Kütüphanesi Osmanlıca Makaleler Veri Tabanından erişilmiştir.
Bulgular: Osmanlı süreli yayınlarında yer alan makalelerde bilgi bilimleri alanındaki mesleki uygulamaların detaylarına girilmediği, çoğunlukla arşiv, müze ve kütüphanelerde bulunan bilgi kaynakları hakkında tanıtıcı bilgi verildiği tespit edilmiştir.
Sonuç: Çalışma sonucunda incelenen makalelerin bilgilendirme ve tanıtım amaçlı yazıldığı sonucuna ulaşılmıştır. Bu nedenle ülkemizdeki mesleki gelişime ve alan yazına katkıları sınırlı olmuştur.
Özgünlük: Bilgi bilimleri alanında Osmanlı süreli yayınlarında Batı’daki bilgi kurumları ile ilgili makaleleri değerlendiren ilk yayın olması çalışmanın özgün yanını oluşturmaktadır.
Colorimetric-Based Concentration Measurement of Manganese Ions using Spectroscopy Approach
Authors: Abd Rahman Mohamad Faizal
Published: September 2023

This paper presents the spectroscopy analysis of manganese ions (Mn2+) to investigate the correlation between its concentration and optical absorbance at different wavelength spectra. This work was performed as a preliminary work to establish guidelines and references for future work in developing a monochromatic light-based colorimetric system for concentration measurement of Mn2+. The samples were prepared at the concentration range of 0.2–1.0 ppm using a colorimetric reagent (i.e., 0.1 % PAN solution) that produced an orange-based coloured solution. Qualitative analysis was performed to obtain the absorbance spectra, which are significant in identifying the suitable colour of monochromatic light (e.g., LED), as well as to predict the settling time for steady-state condition before the measurement could be taken. The results showed that for the range of concentration studied, the blue to cyan region gives the best absorbance with peak absorbance wavelength occurred at around 495 nm. Testing at the time interval between 30 and 90 min after sample preparation also gives the indication of the steady-state condition for a complete colorimetric reaction. Then, quantitative analysis was performed to obtain a standard calibration curve that relates optical absorbance and Mn2+ concentration. The curve is significant to serve as a standard reference for the results to be obtained during colorimetric system development. The calibration curve gives a good linearity at R2 = 0.99, thus verifying the sample preparation and measurement procedures, as well as instrumentation setting used in this work.
Ensuring the stability of banks in the context of national security: Tasks for Ukraine
Authors: Mykolaichuk Mykola , Lesyk Olena , Todorova Olha
Published: September 2023

The purpose of the study is the theoretical and methodological substantiation of the mechanism of forming the stability of banks as a component of state regulation of the state of national security. The research methodology is based on comparing the approaches of different countries to the formation of the national security system, identifying standard features and individual characteristics depending on national interests and the conditions of their socio-economic development. The results of the analysis of the experience of different countries are the basis for recognising the importance of Ukraine in ensuring the stability of banks, which depends on the possibility of crediting businesses and citizens, making non-cash payments, and paying pensions, including temporarily occupied territories. Identifying the factors affecting the stability of banks in the conditions of crisis phenomena and choosing the methodology for assessing the strength of banks made it possible to select the most effective instruments for influencing the stability of banks and to outline the tasks for Ukraine. In addition, the monitoring of indicators of the strength of banks and achievements in the sustainable development of the state and regions contribute to the assessment of the effectiveness of public administration at the appropriate levels.
Use of mathematical optimization to construct optimal reservoir operating rules—A case study of the Barna reservoir in Narmada Basin, India
Authors: Ilich Nesa
Published: September 2023

This paper explains the benefits of using mathematical optimization to construct high performance reservoir operating rules and the related water rationing (deficit sharing) policies. The principal idea of the proposed approach is to generate perfect solutions obtained from an LP-based optimization model with the assumed foreknowledge of inflows represented with historical natural flows that are matched in the model with the current or projected levels of water demands. Water demands may include a mix of on-stream (e.g., e-flow targets or hydro power) and off-stream demands (irrigation or industry). The paper demonstrates the benefits of the proposed methodology by developing and testing short term operating rules on the Barna reservoir in Narmada River Basin in India. It shows that it is possible to achieve simulated results that follow the proposed rules and differ by only 2.5% in terms of the mean annual deficits from the best possible performance obtained using mathematical optimization with full foreknowledge of inflows.
L’activité des stagiaires en éducation physique et sportive à travers des situations émotionnellement marquantes vécues en stage
Authors: Descoeudres Magali
Published: September 2023

Cette étude vise à comprendre le développement de l’activité des stagiaires en EPS à partir de situations émotionnellement marquantes. La première partie a pour but de dessiner une topographie des situations émotionnellement marquantes provenant de 139 stagiaires en EPS. La deuxième partie, clinique, auprès de cinq stagiaires, vise à comprendre comment les situations émotionnellement marquantes freinent ou favorisent le développement de leur activité. Les résultats montrent que les stagiaires en EPS vivent des situations émotionnellement marquantes qui favorisent surtout un développement par la maîtrise de nouvelles opérations. Les résultats ouvrent des pistes concernant les dispositifs actuels de la formation par alternance, notamment par une prise en compte de la dimension subjective du métier.
The connection between assessment and learning outcomes
Authors: Bara Enkelejda , Bara Gëzim
Published: September 2023

Introduction: When learning outcomes are written, it is important that they are written in a way that they can be assessed. Clearly, it is necessary to have some form of assessment tool or technique to determine the extent to which learning outcomes have been achieved. The challenge for teachers is to ensure that there is alignment between teaching methods, assessment techniques, assessment criteria and learning outcomes. This link between teaching, assessment and learning outcomes helps to make the overall learning experience more transparent.

Purpose: To describe assessment techniques and see if there is an alignment between teaching methods, assessment techniques, assessment criteria and learning outcomes.

Materials and methods: Analysis of assessment techniques used by teachers at “Isa Boletini” secondary school, Tirana. Two aspects were used to carry out the research: student survey and teacher survey (interview). These surveys aimed to see if students are helped to understand how they should achieve learning outcomes and how clearly the assessment techniques and assessment criteria are defined by the teacher.

Results: From the analysis of gender data, (45%) were male and (55%) were female. The age group surveyed is 16-18 years old. 100 students participated in the study. The analysis of the students’ survey shows that the answers given by them state that teachers use diverse methods during teaching and do not stick strictly to traditional teaching. The analysis of the teachers’ survey shows that they find it difficult to coordinate or align teaching methods, assessment techniques, assessment criteria and learning outcomes, since most students are not interested during the lesson, they do not have cooperation with each other, or the spirit of group work, thus making it difficult to increase the performance of the students and their maximum involvement during the teaching process.

Conclusion: The use of appropriate teaching and assessment strategies leads to more accurate and clear learning outcomes. The quality of teaching increases when students can interact with teachers and teachers show genuine interest in solving their problems.
Analysis of Entrepreneurial Behaviour in Incubated Technology-Based Companies
Authors: de Freitas Michelin Claudia , Minello Italo Fernando , Siluk Julio Cezar Mairesse , Gerhardt Vinícius Jaques , Savian Fernando de Souza , Garlet Taís Bisognin
Published: September 2023

Background

The analysis of entrepreneurial behaviour in incubated technology-based companies can help managers to understand their characteristics and how these aspects can be maximized to increase the performance of the companies.

Objectives

This study proposes to measure the entrepreneurial behaviour of managers of technology-based companies in incubators in southern Brazil facing different stages of the business life cycle.

Methods/Approach

The Analytic Hierarchy Process is used to measure the entrepreneurial behaviour index of technology-based companies’ managers throughout the stage of the business life cycle.

Results

In the early stages, entrepreneurs have ample self-confidence and are willing to make quick decisions. In the intermediate stages, the entrepreneur shows greater persistence and effort in the tasks. In the later stages, the entrepreneur acquires a greater sense of group activity and punctuality in completing tasks.

Conclusions

This study analyses how managers demonstrate their entrepreneurial behaviour as the stages the company experiences. The results can help managers better understand their performance and actions reflected through their behaviours.
Shedding light on weight loss: A narrative review of medications for treating obesity
Authors: Darapaneni Haritha , Lakhanpal Samridhi , Chhayani Hiren , Parikh Kinna , Patel Meet , Gupta Vasu , Anamika Fnu , Munjal Ripudaman , Jain Rohit
Published: September 2023

Obesity and overweight are the major risk factors for numerous chronic diseases, including cardiovascular diseases such as heart disease and stroke, which are the leading causes of death worldwide. The prevalence of obesity has dramatically risen in both developed and developing countries, making it a significant public health concern and a global crisis. Despite lifestyle modifications being the first-line treatment, the high risk of relapse has led to a growing interest in non-invasive pharmacotherapeutic interventions to achieve and maintain weight loss and reverse the growth of the obesity epidemic. Cardiovascular diseases and cancer account for the highest mortality rates among other comorbidities associated with obesity and overweight. Excess and abnormally deposited adipose tissue secretes various inflammatory mediators, leading to cardiovascular diseases and cancers. Weight loss of 5–10% significantly reduces cardiometabolic risk. Medications currently approved in the USA for long-term management of obesity are orlistat, naltrexone, bupropion, phentermine/topiramate, and Glucagon Like Peptide-1 (GLP-1) agonists such as liraglutide and semaglutide. The benefit-to-risk of medications, comorbidities, and individual responses should guide the treatment decisions. The article provides a comprehensive overview and discussion of several weight loss medications used previously and currently, including their efficacy, mechanisms of action, and side effects.
Ist der Staat der bessere Arbeitgeber?
Authors: Prümer Stephanie , Schnabel Claus
Published: September 2023

A comparison of working conditions in the public and private sectors shows that working time regulations in the public sector are more employee-friendly and that the protection of the workforce through collective agreements and co-determination is more comprehensive. However, in terms of wages, the public sector only offers advantages for women, while men are better off in the private sector. In order to persist in the growing competition for employees, the public sector should emphasise more strongly its importance as an employer, further boost its attractiveness for employees, and reinforce its attempts to retain employees.
Schieneninfrastruktur: Replik und Erwiderung
Authors: Becker Jonas
Published: September 2023

In the May 2023 issue, Wirtschaftsdienst published an essay entitled “Rail Infrastructure: Little Courage for Radical Reforms” by Alexander Eisenkopf. Jonas Becker takes a different view in a reply, followed by Alexander Eisenkopf explaining his position in a rejoinder.
Zuwanderung in akademischen MINT-Berufen – zunehmende Bedeutung und erste Erfolge
Authors: Plünnecke Axel
Published: September 2023

More STEM graduates are needed to meet the challenges of demography, decarbonisation, digitalisation and deglobalisation. However, the domestic supply threatens to decline, making immigration even more important. Over the past decade, there has been a significant increase in the proportion of foreign workers in academic STEM professions, particularly individuals from third countries like India. Particularly in southern Germany, the share of foreigners in engineering employment has risen; less so in eastern Germany. However, there are also initial successes in the east, for example in the Ilm district, the proportion of foreigners rose sharply due to international companies and the Technical University. To attract more immigrants in STEM, the immigration process should be accelerated and international students at universities should be supported and encouraged to stay in Germany.
Valor económico del agua en el Distrito de Riego 003 Tula, Hidalgo, México
Authors:   Universidad Autónoma Chapingo, Texcoco, Estado de México, México, Hernández-Pérez Jonathan , Arana-Coronado Oscar A. ,   Colegio de Postgraduados, Montecillo, Estado de México, México, Hernández-Ortiz Juan ,   Universidad Autónoma Chapingo, Texcoco, Estado de México, México, Valdivia-Alcalá Ramón ,   Universidad Autónoma Chapingo, Texcoco, Estado de México, México
Published: September 2023

Ante el incremento en la demanda de agua para riego en los últimos años, se necesitan tomar medidas de política que contribuyan al uso y asignación eficiente del recurso agua en la agricultura. El objetivo de la presente investigación fue determinar el valor económico del agua en el distrito de riego 003 Tula, Hidalgo, en diferentes escenarios de escasez de acuerdo con el patrón de cultivos del año agrícola 2020-2021. Se utilizó un modelo de programación lineal y se resolvió con el método Simplex con la herramienta de análisis Solver® de Microsoft Office Excel®. Al reducir la disponibilidad de agua en el DR003 Tula del 100% al 50%, el precio sombra pasa de 0.64 a 0.91 $/m3 de agua, se reduce la superficie sembrada total en 50.2% y la superficie de cebada forrajera, rye grass, avena forrajera y bermuda.
Glanüler tip megameatus intakt sünnet derisi olan olgularda tedavi ne olmalıdır?
Authors: Yalçın Kenan
Published: September 2023

OBJECTIVES: We aimed to evaluate the treatment options in patients with glanular type megameatus intact foreskin. MATERIAL and METHODS: Between 2011 and 2021, more than 5000 circumcision procedures were performed in our clinic. The treatment options of 70 cases with glanular type megameatus, which we encountered incidentally when the foreskin was retracted during the circumcision procedure and sometimes we did not know exactly what to do at that moment, were found to be treated retrospectively. Glans approximation procedure (GAP) was applied to 14 of 24 patients who accepted hypospadias surgery. Meatal advancement and glanuloplasty procedure (MAGPI) was performed in 10 of them. The mean age, duration of surgery and surgical intervention results of the cases were evaluated. RESULTS: The mean age of the patients who underwent the GAP procedure was 4.7±1.9, and the duration of surgery was 59.1±6.3 minutes. Urethral stenosis was seen in 1 of 14 cases and urethral fistula complication was observed in 1 of them. The mean age of the patients who underwent the MAGPI procedure was 4.3±1.4, and the duration of surgery was 64.3±3.03 minutes. Urethral stenosis was seen in 1 of 10 cases and unsuccessful surgical complication was observed in 1 of them. Complications developed in 4 (16.66%) of 24 patients. 4 patients underwent re-operation. There was no significant difference in the mean age, duration of surgery and complication rates between the two techniques. CONCLUSION: Intact foreskin conceals clinical findings and megameatus can usually be detected at circumcision attempt. Although the surgery for the glanular type, which is the mildest form of megameatus, is controversial, satisfactory results can be obtained with the appropriate surgical method. In addition, detailed interviews should be made with families before surgery and it should be explained that the operation is controversial. Keywords: glanular, hypospadias, intact foreskin, megameatus
ESWT’nin erektil disfonksiyon tedavisindeki rolü
Authors: Ergün Kasım Emre , Kızılay Fuat
Published: September 2023

Oral phosphodiesterase 5 (PDE 5) inhibitors, vacuum pumps, intraurethral drugs, intracavernosal injections, and penile prosthesis implantation are currently accepted treatments for erectile dysfunction (ED). In 2010, low-intensity extracorporeal shock wave therapy (Li-ESWT) was introduced by Vardi as a noninvasive method for the treatment of ED. Since the important mechanism of ED is vascular endothelial dysfunction and Li-ESWT can stimulate the expression of angiogenesis-related factors such as vascular endothelial growth factor (VEGF) to support vascular regeneration, the use of Li-ESWT in the treatment of ED is becoming widespread. Currently, there is no standard treatment protocol for Li-ESWT. Li-ESWT appears to have the potential to be an option for the treatment of ED, particularly in patients who respond poorly to oral medications and do not want more invasive procedures. On the other hand, further studies are needed to understand which patients may benefit most from the treatment and which protocol will produce the best results. Keywords: low-intensity extracorporeal shock wave therapy, erectile dysfunction, international index of erectile function-5 score
Alfa blokerlerin ejakülasyon üzerine etkisi: Literatür güncellemesi
Authors: Yorulmaz Enis Mert , Dönmez Kürşad , Köse Osman , Özcan Serkan , Görgel Sacit Nuri , Akın igit
Published: September 2023

Ejaculation disorders are a complex and multifactorial condition that can significantly impact individuals’ quality of life. Alpha blockers, which are used in the treatment of benign prostatic hyperplasia (BPH), are associated with various sexual side effects, including changes in ejaculation. In this review, the physiological mechanisms and clinical outcomes of the effects of alpha blockers on ejaculation, as documented in the literature, are discussed. Keywords: alpha blocker, benign prostatic hyperplasia, ejaculation
PERAN GURU DAN ORANG TUA TERHADAP STIMULASI KEAKSARAAN ANAK USIA DINI
Authors: Isma Ulfadilah  , Darmiyanti Astuti
Published: September 2023

The research method used is a reference-based literature or library study that is relevant to the topic of the problem and of course varies. The purpose of this study is to determine the role of teachers or parents when stimulating early childhood literacy. Early literacy is one aspect of language development in early childhood. Language and literacy are inextricably linked. The ability of the underlying skills of children begins when the little child feels colors, shapes, understands images, understands pictures, false letters towards the beginning of his name records the letters of his name, notes his considerations despite the fact that the letters are still turbulent or fragmented, pronounces words that most of the time are repeated in a storybook, spelling letters, reading without others, the relationship of sounds to letters, referring to the names of numbers can be indicated by pictures. Methods or methods in literacy, namely: ability in literacy, building reading habits, writing, parental stimulation, implementing learning, creating a language-rich environment, early literacy skills and basic early childhood numeracy, learning media and pre-literacy learning. Without language, a person cannot communicate with others, therefore language plays an important role in allowing people to communicate with each other. This is in line with the belief that various forms of media have a positive effect on the child's thinking and concentration, fine motor skills (eye and hand coordination), patience, language skills, the skill of understanding meaning and knowledge of vocabulary.
MANAJEMEN PEMBELAJARAN BERBASIS PROJEK PADA PENDIDIKAN ANAK USIA DINI
Authors: Hanita Hanita , Suryono Yoyon , Yanti Fauziah Puji
Published: September 2023

Learning management is a reference for teachers in carrying out a learning implementation. Project-based learning also has steps and implementation procedures. So in this study we want to examine in depth how to implement project learning in education, especially in early childhood education. The research method used is literature review and will use the PRISMA checklist to determine the selection of studies that have been found and adapted to the objectives of the literature review. The results of the research Project-based learning management in early childhood education has different procedures and procedures. The same concept is only at the planning, implementation and evaluation stages, which are indeed stages in the learning process. From several researches it is still found that project-based learning from the point of view of the initial originator of the project method, namely William H. Kilpatrick, is still lacking. The conclusions on the implementation of project learning in early childhood are diverse. But still through planning, implementation and evaluation. However, this is still considered far from the steps that were originally applied by the originator of the project method, namely William H. Kilpatrick. This change was due to the many theoretical developments of William H. Kilpatrick's project method.
KAJIAN YURIDIS TENTANG RELEVANSI MALPRAKTIK MEDIS DENGAN TINDAK PIDANA UMUM
Authors: Gunawan Sinatra
Published: September 2023

Meningkatnya ketidakpuas pasien terhadap pelayanan dokter menyebabkan meningkatnya teguran, somasi dan gugatan, baik dilakukan secara langsung atau melalui media cetak atau elektronik. Pandangan masyarakat tentang malpraktik dokter adalah ungkapan tentang suatu kesalahan dokter yang tidak dapat ditoleransi kesalahannya.  Walaupun saat sekarang praktik dokter berupa tatap muka secara online. Terdapat 298 pengaduan kasus sengketa medis sejak sejak 2016 sampai 25 Juni 2021. Dari hal tersebut timbul permasalahan tentang relevansi malpraktik medis saat ini dengan tindak pidana umum dalam perundang-undangan. Jenis penelitian yuridis normatif dengan pendekatan kepustakaan, pendekatan kasus dan pendekatan konseptual. Hasil penelitian ini dapat bermanfaat sebagai pedoman bagi semua penegak hukum dan atau badan peradilan dan atau organisasi induk dokter dan atau advokat medis. Ditemukan bahwa semua perundang-undangan yang ada saat ini belum mengatur keseluruhan tentang perbuatan atau peristiwa hukum dengan subjek hukum seorang dokter yang melaksanakan pekerjaan profesinya seperti tercantum pada Undang-Undang Nomor 29 Tahun 2004, Peraturan Menteri Kesehatan Nomor 2052 Tahun 2011, Undang-Undang Nomor 8 Tahun 1999, dan Kode Etik Kedokteran.  Memaksakan kasus malpraktik medis menggunakan Kitab Undang-Undang Hukum Pidana dan menyetarakan sebagai tindak pidana umum. Hal ini bersinggungan dengan asas hukum yang berlaku