bluuebunny/crossref_metadata_2025 huggingface dataset:
Low-dose aspirin to prevent preeclampsia and growth restriction in nulliparous women identified by uterine artery Doppler as at high risk of preeclampsia: A double blinded randomized placebo-controlled trial
Authors: Diguisto Caroline , Le Gouge Amelie , Marchand Marie-Sara , Megier Pascal , Ville Yves , Haddad Georges , Winer Norbert , Arthuis Chloé , Doret Muriel , Debarge Veronique Houfflin , Flandrin Anaig , Delmas Hélène Laurichesse , Gallot Denis , Mares Pierre , Vayssiere Christophe , Sentilhes Loïc , Cheve Marie-Therese , Paumier Anne , Durin Luc , Schaub Bruno , Equy Veronique , Giraudeau Bruno , Perrotin Franck ,   for the Groupe de Recherche en Obstétrique et Gynécologie (GROG)
Published: October 2022

Introduction

This trial evaluates whether daily low-dose aspirin initiated before 16 weeks of gestation can reduce preeclampsia and fetal growth restriction in nulliparous women identified by first-trimester uterine artery Dopplers as at high risk of preeclampsia.

Methods

This randomized, blinded, placebo-controlled, parallel-group trial took place in 17 French obstetric departments providing antenatal care. Pregnant nulliparous women aged ≥ 18 years with a singleton pregnancy at a gestational age < 16 weeks of gestation with a lowest pulsatility index ≥ 1.7 or a bilateral protodiastolic notching for both uterine arteries on an ultrasound performed between 11+0 and 13+6 weeks by a certified sonographer were randomized at a 1:1 ratio to 160 mg of low-dose aspirin or to placebo to be taken daily from inclusion to their 34th week of gestation. The main outcome was preeclampsia or a birthweight ≤ 5th percentile. Other outcomes included preeclampsia, severe preeclampsia, preterm preeclampsia, preterm delivery before 34 weeks, mode of delivery, type of anesthesia, birthweight ≤ 5th percentile and perinatal death.

Results

The trial was interrupted due to recruiting difficulties. Between June 2012 and June 2016, 1104 women were randomized, two withdrew consent, and two had terminations of pregnancies. Preeclampsia or a birthweight ≤ 5th percentile occurred in 88 (16.0%) women in the low-dose aspirin group and in 79 (14.4%) in the placebo group (proportion difference 1.6 [-2.6; 5.9] p = 0.45). The two groups did not differ significantly for the secondary outcomes.

Conclusion

Low-dose aspirin was not associated with a lower rate of either preeclampsia or birthweight ≤ 5th percentile in women identified by their first-trimester uterine artery Doppler as at high risk of preeclampsia.

Trial registration

(NCT0172946).
A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity
Authors: Hagemann Christoffer A. , Legart Christian , Møllerhøj Mathias B. , Madsen Martin R. , Hansen Henrik H. , Kønig Merete J. , Helgstrand Frederik , Hjørne Flemming P. , Toxværd Anders , Langhoff Jill L. , Kielgast Urd L. , Gluud Lise L. , Ægidius Helene , Rigbolt Kristoffer T. G. , Vilsbøll Tina , Jelsing Jacob , Knop Filip K.
Published: October 2022

Non-invasive biomarkers of non-alcoholic fatty liver disease (NAFLD) supporting diagnosis and monitoring disease progression are urgently needed. The present study aimed to establish a bioinformatics pipeline capable of defining and validating NAFLD biomarker candidates based on paired hepatic global gene expression and plasma bioanalysis from individuals representing different stages of histologically confirmed NAFLD (no/mild, moderate, more advanced NAFLD). Liver secretome gene signatures were generated in a patient cohort of 26 severely obese individuals with the majority having no or mild fibrosis. To this end, global gene expression changes were compared between individuals with no/mild NAFLD and moderate/advanced NAFLD with subsequent filtering for candidate gene products with liver-selective expression and secretion. Four candidate genes, includingLPA(lipoprotein A),IGFBP-1(insulin-like growth factor-binding protein 1),SERPINF2(serpin family F member 2) andMAT1A(methionine adenosyltransferase 1A), were differentially expressed in moderate/advanced NAFLD, which was confirmed in three independent RNA sequencing datasets from large, publicly available NAFLD studies. The corresponding gene products were quantified in plasma samples but could not discriminate among different grades of NAFLD based on NAFLD activity score.Conclusion: We demonstrate a novel approach based on the liver transcriptome allowing for identification of secreted hepatic gene products as potential circulating diagnostic biomarkers of NAFLD. Using this approach in larger NAFLD patient cohorts may yield potential circulating biomarkers for NAFLD severity.
Identifying the impact of social influences in health-related discrete choice experiments
Authors: de Bekker-Grob Esther W. , Howard Kirsten , Swait Joffre
Published: October 2022

Several disciplines, among them health, sociology, and economics, provide strong evidence that social context is important to individual choices. It is therefore surprising that relatively little research has been focused on integrating the effect of social influence into choice models, especially given the importance of such choices in healthcare. This study developed and empirically tested a choice model that accounts for social network influences in a discrete choice experiment (DCE). We focused on maternal choices for childhood vaccination in Australia, and used an econometric choice model that explicitly 1) incorporated vaccine schedule characteristics, benefits and costs, and 2) represented up to ten different identifiable key influencer types (e.g., partner, parents, friends, healthcare professionals, inter alia), allowing for the attribution of directional importance of each influencer on the gravid woman’s decision to adhere to or reject childhood vaccination. Pregnant women (N = 604) aged 18 years and older recruited from an online panel completed a survey, including a DCE and questions about key influencers. A two-class ordered latent class model was conducted to analyse the DCE data, which assumes that the underlying latent driver (in our case the WHO vaccine hesitancy scale) is ordered, to give a practical interpretation of the meaning of the classes. When the choice model considered both childhood vaccination attributes and key influencers, a very high model fit was reached. The impact of key influencers on maternal choice for childhood vaccination was massive compared to the impact of childhood vaccination attributes. The marginal impact differed between key influencers. Our DCE study showed that the maternal decision for childhood vaccination was essentially almost completely socially driven, suggesting that the potential impact of social network influences can and should be considered in health-related DCEs, particular those where there are likely to be strong underlying social norms dictating decision maker behaviour.
Glycocalyx degradation and the endotheliopathy of viral infection
Authors: Taghavi Sharven , Abdullah Sarah , Shaheen Farhana , Mueller Lauren , Gagen Brennan , Duchesne Juan , Steele Chad , Pociask Derek , Kolls Jay , Jackson-Weaver Olan
Published: October 2022

The endothelial glycocalyx (EGX) contributes to the permeability barrier of vessels and regulates the coagulation cascade. EGX damage, which occurs in numerous disease states, including sepsis and trauma, results in endotheliopathy. While influenza and other viral infections are known to cause endothelial dysfunction, their effect on the EGX has not been described. We hypothesized that the H1N1 influenza virus would cause EGX degradation. Human umbilical vein endothelial cells (HUVECs) were exposed to varying multiplicities of infection (MOI) of the H1N1 strain of influenza virus for 24 hours. A dose-dependent effect was examined by using an MOI of 5 (n = 541), 15 (n = 714), 30 (n = 596), and 60 (n = 653) and compared to a control (n = 607). Cells were fixed and stained with FITC-labelled wheat germ agglutinin to quantify EGX. There was no difference in EGX intensity after exposure to H1N1 at an MOI of 5 compared to control (6.20 vs. 6.56 Arbitrary Units (AU), p = 0.50). EGX intensity was decreased at an MOI of 15 compared to control (5.36 vs. 6.56 AU, p<0.001). The degree of EGX degradation was worse at higher doses of the H1N1 virus; however, the decrease in EGX intensity was maximized at an MOI of 30. Injury at MOI of 60 was not worse than MOI of 30. (4.17 vs. 4.47 AU, p = 0.13). The H1N1 virus induces endothelial dysfunction by causing EGX degradation in a dose-dependent fashion. Further studies are needed to characterize the role of this EGX damage in causing clinically significant lung injury during acute viral infection.
Emergence of sector and spiral patterns from a two-species mutualistic cross-feeding model
Authors: Lin Jiaqi , Sun Hui , Dong JiaJia
Published: October 2022

The ubiquitous existence of microbial communities marks the importance of understanding how species interact within the community to coexist and their spatial organization. We study a two-species mutualistic cross-feeding model through a stochastic cellular automaton on a square lattice using kinetic Monte Carlo simulation. Our model encapsulates the essential dynamic processes such as cell growth, and nutrient excretion, diffusion and uptake. Focusing on the interplay among nutrient diffusion and individual cell division, we discover three general classes of colony morphology: co-existing sectors, co-existing spirals, and engulfment. When the cross-feeding nutrient is widely available, either through high excretion or fast diffusion, a stable circular colony with alternating species sector emerges. When the consumer cells rely on being spatially close to the producers, we observe a stable spiral. We also see one species being engulfed by the other when species interfaces merge due to stochastic fluctuation. By tuning the diffusion rate and the growth rate, we are able to gain quantitative insights into the structures of the sectors and the spirals.
Analytical-stochastic model of motor difficulty for three-dimensional manipulation tasks
Authors: Lucchese Andrea , Digiesi Salvatore , Mummolo Carlotta
Published: October 2022

Multiple models exist for the evaluation of human motor performance; some of these rely on the Index of Difficulty (ID), a measure to evaluate the difficulty associated to simple reaching tasks. Despite the numerous applications of the ID in reaching movements, the existing formulations are functions of the geometrical features of the task and do not consider the motor behaviour of subjects performing repetitive movements in interaction with the environment. Variability of movements, length of trajectories, subject-specific strength and skill, and required interaction with the environment are all factors that contribute to the motor difficulty experienced by a moving agent (e.g., human, robot) as it repeatedly interacts with the environment during a given task (e.g., target-reaching movement, locomotion, etc.). A novel concept of motor difficulty experienced by an agent executing repetitive end-effector movements is presented in this study. A stochastic ID formulation is proposed that captures the abovementioned factors and applies to general three-dimensional motor tasks. Natural motor variability, inherent in the proposed model, is representative of the flexibility in motor synergies for a given agent-environment interaction: the smaller the flexibility, the greater the experienced difficulty throughout the movement. The quantification of experienced motor difficulty is demonstrated for the case of young healthy subjects performing three-dimensional arm movements during which different objects are manipulated. Results show that subjects’ experienced motor difficulty is influenced by the type of object. In particular, a difference in motor difficulty is observed when manipulating objects with different grasp types. The proposed model can be employed as a novel tool to evaluate the motor performance of agents involved in repetitive movements, such as in pick and place and manipulation, with application in both industrial and rehabilitation contexts.
Determinants of human capital development in Ethiopian economy: Theory and empirical evidence
Authors: Mengesha Zemed Degu , Singh Lakhwinder
Published: October 2022

In line with the basic tenets of human capital development theory, the present study examines and presents the determinants of human capital development (Human Development Index [HDI]) in Ethiopia using time-series data from 1980/81 to 2019/20. Based on the Augmented Dickey–Fuller and Phillips–Perron unit root test results, the Autoregressive Distributed Lag (ARDL) bounds co-integration and error correction models are employed. The bounds test indicated the existence of significant long-run equilibrium relationship between HDI and its human capital input indicators. Results of the estimated long-run selected model indicated that public recurrent expenditure on education and health as well as its capital education expenditures and basic health coverage have a positive and significant contribution in improving the HDI of the country. On the contrary, government development expenditure on health, population–physician, student–school and age dependency ratios has an adverse effect on human capital development of Ethiopia. On the other hand, the short-run error correction model showed that a temporary disequilibrium level of HDI in the previous period is corrected by approximately 79.37 per cent in the current period to restore to a long-run equilibrium. Thus, a concerted effort is needed to expand and use public expenditure on education and health in an economic, accountable and transparent way. Furthermore, the turnover level of qualified teachers and medical doctors has to be reduced in addition to building and upgrading adequate quality education and health infrastructures and facilities in the economy.
Role of the Digital Technology in accelerating the growth of micro, small and medium enterprises in Uttarakhand: Using TAM (Technology Acceptance Model)
Authors: Rawat Ravindra Singh , Kothari Hem Chandra , Chandra Deep
Published: October 2022

The purpose of this study is to examine how can Digital Technology accelerate the growth of micro, small and medium enterprises in Uttarakhand by adopting the latest yet cost-effective Digital Technologies in their business models, enabling the marketers to connect with their prospective customers effectively and obtain business objectives. Data from 60 micro, small and medium enterprises owners had been collected through an online questionnaire. Technology Acceptance Model (TAM) was used to develop hypotheses, and the statistical tool ‘t-test and ANOVA’ were used for data analysis and their proper assessment. The research findings revealed that Digital Technology plays a vital role in the growth of small businesses irrespective of their year of establishment, nature and stages of business i.e. ‘growth’, ‘stable’ and ‘slowdown’. It is the best practice across the functional area of businesses; viz. marketing, finance, human resources and general business-related activities for yielding lucrative results and achieving business objectives.
O Regime Florestal em Serpins: Exposicão e Critica
Authors: Carvalho Adriano J. de
Published: October 2022

Mais de cem anos separam o livro original da reedição atual.
Trata-se de uma obra com relevância científica, social e humana, que talvez nos possa ajudar a reenquadrar problemas para os quais não há solução à vista: as alterações climáticas, as relações humanas desiguais e a magra possibilidade (ou mesmo a impossibilidade) de as pessoas cooperarem para produzir, conservar e melhorar um lugar ao qual pertencem.
Curación digital y género en la Ciencia de la Información
Authors:   Universidade Estadual Paulista,   Universidad de Salamanca, Martínez-Ávila Daniel ,   Universidad de León, Landim Laís Alpi ,   Unesp
Published: October 2022

El mundo de las presencias es simulado, presentado y representado en el medio digital. En el contexto de la comunicación digital-virtual, y a partir de las recientes transformaciones en sus soportes, las colecciones multimodales de información pasan a un estado en el que el acceso de los sujetos informacionales a la información se puede facilitar y ampliar. En tal universo, la información y los datos representados necesitan tratamientos conceptuales y técnicos que respeten la naturaleza y las particularidades de los medios y de los lenguajes que transitan por ellos. Además, al ser procesados en un medio frágil como es el digital, la información codificada para medios electrónicos también requiere de procedimientos y cuidados dirigidos a su preservación integral. En la Ciencia de la Información, el conjunto de procedimientos continuos e iterativos destinados a satisfacer las demandas de atención para optimizar el acceso y la preservación se denomina Curación Digital: un complejo de procesos que van desde el design inicial y conceptualización hasta la designación de metadatos, la evaluación de decisiones de preservación o descarte, la transformación, el acceso, el intercambio y la reevaluación de objetos digitales. En temas relacionados con el género, la necesidad de la Curación Digital de la información presentada en medios electrónicos se torna urgente, dados los dramáticos hechos que preocupan por la falta de información, o por la desinformación, en los múltiples territorios que abarca el concepto. En ellos, la información debe ser procesada con el propósito sociocultural de realizar la creación de estrategias e instrumentos para superar los innumerables desafíos e injusticias presentes.
«Design» y curación digital para un espacio virtual de personas con discapacidad visual
Authors:   Católica do Rio de Janeiro, Portugal Cristina , Moura Mônica ,   Universidade Estadual Paulista, Guimarães Márcio ,   Universidade Federal do MaranhãoI, Perez Iana Uliana ,   Universidade Estadual Paulista, Junior José Carlos Magro ,   Universidade Estadual Paulista
Published: October 2022

El capítulo presenta el proceso de curación digital del proyecto piloto “Me acordé de ti” a través del cual se estableció una red de voluntarios responsables de la organización, lectura y producción de audios para personas con y sin discapacidad visual, especialmente para ancianos, durante y después de la pandemia para paliar estados de soledad y brindar a las personas con discapacidad visual el acceso a cuentos, poemas, entre otros aportes del grupo de lectores voluntarios. El objetivo es promover la ciudadanía y la constitución de la autonomía del público atendido a partir de los conceptos teóricos y estéticos, del despertar de recuerdos y memorias que ayuden a las personas ciegas a elaborar imágenes mentales y las asistan en los procesos de ampliación del repertorio de conocimiento, integración social, mejora de la calidad de vida y bienestar, atendiendo el alcance del design inclusivo y del design con responsabilidad social.
El papel de la preservación digital en la curación digital
Authors:   Universidade Estadual Paulista, Grácio José Carlos Abbud , Madio Telma Campanha de Carvalho ,   Universidade Estadual Paulista
Published: October 2022

La información ha sido producida cada vez más en forma digital y sus características demandan nuevas formas de preservar y proporcionar su acceso. El desafío actual es cómo preservar la información digital ante los cambios y avances constantes, garantizando su autenticidad. El campo de la preservación digital es multidisciplinar e involucra aspectos: técnicos, relacionados con la selección de lo que preservar, la utilización de modelos y estándares, el montaje de la infraestructura tecnológica de preservación y acceso, la aplicación de las estrategias adecuadas, al uso del soporte adecuado y la representación por metadatos; organizacionales, relativos a las actividades de gestión; legales, que tratan de cuestiones como derechos de autor, leyes, normas y recomendaciones; culturales, relacionados con la capacidad de asimilación de los cambios que la preservación digital genera en todo el proceso informacional. Este capítulo presenta los conceptos que fundamentan la preservación digital, detalla sus aspectos y cómo estos están relacionados con el ciclo de vida de la Curación Digital.
La recuperación de información: la representación de lo subjetivo
Authors:   Universidade Estadual Paulista, Ferneda Edberto
Published: October 2022

La recuperación de información designa la operación mediante la cual se seleccionan los documentos de una colección en función de una demanda determinada de información. Se recupera un documento si su representación coincide total o parcialmente con la representación de la necesidad del usuario. La correcta interpretación de tales representaciones es fundamental para la eficiencia de un sistema de información, que involucra procesos cuya formalización y automatización solo son posibles por medio de simplificaciones de conceptos típicamente subjetivos. Estas simplificaciones afectan directamente en la eficiencia de los sistemas de información. Este trabajo presenta y evalúa las formas de representación computacional de los conceptos y operaciones que hacen parte del proceso de recuperación de información. La automatización del proceso de recuperación de información viabiliza la operación de grandes cantidades de datos de forma rápida y ágil, pero no necesariamente proporciona resultados consistentes o satisfactorios. El juicio de relevancia de la información implica procedimientos basados en las capacidades y habilidades humanas de abstracción, aprehensión y representación de su significación.
Recuperar la «fe en la humanidad»: curación de datos, contenido se informaciones en el enfrentamiento de la violencia contra la mujer. Un ensayo preliminar
Authors:   Universidade Federal de Santa Catarina, Vianna William Barbosa , Freitas Maria Cristina Vieira de ,   Universidade de Coimbra, Carvalho Andrea Vasconcelos ,   Universidade Federal do Rio Grande do Norte, Tsunoda Denise Fukumi ,   Universidade Federal do Paraná
Published: October 2022

La violencia contra la mujer es un fenómeno multidimensional e interdisciplinar. Las fuentes para su estudio se encuentran dispersas o en bases de datos parciales, incompletas o desactualizadas y carecen de uniformidad en la indexación. Las medidas correctivas implican diseñar estrategias de búsqueda, de recuperación y de intercambio, involucrando procedimientos de localización de la información, para su selección y seguimiento en campo. ¿Qué estrategias de curación de datos de seguridad pública serán útiles para afrontar este problema? En respuesta, se identifican estudios e iniciativas en un periodo de 15 años. Los resultados demuestran la relevancia de la identificación prematura de víctimas y la activación de protocolos preventivos, empleando inteligencia artificial y aprendizaje de máquina, junto con la integración, la organización y coordinación de datos y actividades. Los estudios futuros deben profundizar el debate sobre la transparencia en la apertura y gobernanza de datos. Como limitación, la invisibilidad y dispersión temática de la literatura científica, lo que perjudica su descubrimiento.
Curación digital en acervos y entornos digitales de museos de lo femenino
Authors:   Universidade Estadual Paulista, Silva Stephanie Cerqueira , Jorente Maria José Vicentini ,   Universidade Estadual Paulista
Published: October 2022

Los acervos de los museos de lo femenino presentan temáticas que amplían las posibilidades de construcción de un protagonismo femenino en diversas prácticas sociales. En ese contexto, se busca entender como la convergencia entre la Curación Digital y la Ciencia de la Información contribuye en la construcción de acervos en entornos digitales, a partir de la organización, presentación y representación de la información, con vistas a su acceso e intercambio. El objetivo general es contextualizar los conceptos y las definiciones de tales áreas, a fin de identificar articulacionesefectivas para la preservación de acervos digitales de los museos de lo femenino. Los resultados demostraron la necesidad de una reflexión sobre la metodología de la planificación pensada en mejoras continuas de acceso e intercambio de la información. Se considera que la implementación de las estrategias y acciones de la Curación Digital para la construcción de acervos en entornos digitales expanden los objetivos de los museos de lo femenino.
Biofilms and efflux pump regulatory gene (mexR) in multidrug-resistant Pseudomonas aeruginosa isolated from migratory birds in Egypt
Authors: Elshafiee Esraa A. , Khalefa Hanan S. , Al-Atfeehy Nayera M. , Amer Fatma , Hamza Dalia A. , Ahmed Zeinab S.
Published: October 2022

Background and Aim: Multidrug-resistant (MDR) Pseudomonas aeruginosa is a global threat to public health. This study aimed to determine biofilms and efflux pump regulatory gene (mexR) in MDR P. aeruginosa isolates.

Materials and Methods: A total of 42 fecal samples of aquatic migratory birds collected during hunting season in Egypt were evaluated for the detection of P. aeruginosa according to standard culture-based methods. The antibiotic susceptibility of P. aeruginosa strains was evaluated using disk diffusion methods. The biofilm formation ability of the isolates was phenotypically determined using a colorimetric microtitration plate assay. Polymerase chain reaction amplification was performed to detect biofilm genes (PelA and PslA) and mexR.

Results: In total, 19 isolates (45.2%) were recovered from the 42 fecal samples of migratory birds. All isolates were identified as MDR P. aeruginosa, and 78.9% of the strains produced biofilms at different degrees. Molecular detection of biofilm extracellular polymeric substances revealed that PelA was the most predominant gene in the biofilm-producing isolates, followed by PslA. mexR was detected in 63.2% of MDR P. aeruginosa isolates, and its prevalence was higher in non–biofilm-producing strains (75%) than in biofilm-producing strains (60%).

Conclusion: Antibiotic resistance in P. aeruginosa isolates recovered from migratory birds through various mechanisms is a major public and animal health problem. It is important to consider the significance of migratory birds in disease transmission.
Chemical Composition and Biological Activities of Essential Oil of
Elsholtzia ciliata obtained at Central Highlands of Vietnam’s Two Seasons
Authors: Nhan Ngu Truong , Thu Le Vu Thi , Thao Nguyen Thi , Phuong Hanh Tran Thi , Luong Ngo Xuan , Cuong To Dao , Hung Dao Viet , Lam Do Tien
Published: October 2022

From the essential oil of the whole plant from Elsholtzia ciliata, obtained by hydrodistillation and
then using gas chromatography/mass spectrometry to analyze and identify 42 constituents, carveol
(26.89%) and z-citral (29.35%) main contents (collected in the dry season time); and 46 constituents,
cis-ocimene (17.95%), carveol (14.84%), Z-citral (17.01%), isocaryophyllene (13.19%) and
trans-caryophyllene (9.76%) as main contents (collected in the rainy season time). The major essential
oils in dry season exhibited good inhibition activity on the Escherichia coli, Bacillus subtilis,
Staphylococcus aureus and Candida albicans with MIC value of 200 μg/mL; exhibited weak cytotoxic
activity on the PC-3 line (IC50 66.34 μg/mL) and A549 line (IC50 93.11 μg/mL). The essential oils in
rainy season exhibited good inhibition activity on the Escherichia coli, Bacillus subtillis and
Saccharomyces cerevisiae with MIC value of 200 μg/mL and Candida albicans with MIC value of
100 μg/mL; displayed good cytotoxic activity on the PC-3 line (IC50 30.62 μg/mL) and Hep-G2 line
(IC50 22.78 μg/mL), however have weak cytotoxic activity on the A549 line (IC50 85.35 μg/mL).
Application of Glucoamylase Hydrolysis with Anaerobically Driven
Microbial Fuel Cells: Effect on Energy Generation from Potato Wastes
Authors: Siddique Md. Nurul Islam , Zaied B.K. , Bin Ibrahim Mohd. Zamri , Ali Noraaini Binti , Rasit Nazaitulshila , Yahya Muhammad Syarifuddin , Ghanem Waheed Ali H. M.
Published: October 2022

A unique dual-phase biological system for producing power from the potato wastes was developed. In
the beginning, commercially available glucoamylase was used to hydrolyze potato wastes resulting
the production of potato waste hydrolyzate. A 100 g of potato waste produced 30 g of hydrolysis solid
and 750 mL of potato waste hydrolyzate. Within 6 h, the maximum glucose generation was 20 g/L
while the maximum COD elimination was 85%. During the second phase, the soluble potato waste
hydrolyzate was utilized to feed microbial fuel cells (MFC), which produced electricity. The maximum
voltage measured was 1.1 V. When the external resistance was 1091 Ω, the power density reached its
greatest point of 93 mW/m3. To evaluate MFC performance, a Coulombic efficiency of 20% was
obtained, thus exploring a new field by converting the high-starch molecules into biofuels, thereby
lowering the cost of commercial biofuel production.
Palladium(II) Complexes with S-Benzyl Dithiocarbazate: Synthesis,
Characterization in vitro Antimicrobial and Anticancer Activities
Authors: Jain Akshita , Meena Ramhari , Sharma Naveen , Belwal Savita , Fahmi Nighat
Published: October 2022

Square planar complexes of palladium(II) were prepared by the reaction of PdCl2 with four different
thio Schiff bases, namely 2-acetyl-pyridine S-benzyl dithiocarbazate (L1H), 2-acetylthiophene-S-benzyl
dithiocarbazate (L2H), 2-acetylfuran-S-benzyl dithiocarbazate (L3H) and 2- acetylnaphthalene-S-benzyl
dithiocarbazate (L4H) in a 1:2 molar ratio. Elemental analysis, molecular weight determinations,
conductance measurements and spectral data, including electronic, IR, 1H and 13C NMR and X-ray
powder diffraction studies, confirmed the formation of palladium(II) complexes. The electrochemical
behaviour of one of the palladium(II) complex has also been determined by cyclic voltammetry. The
antimicrobial activities of the Schiff base ligands and their corresponding palladium(II) complexes
have been tested in vitro against various pathogenic bacterial and fungal strains. The cytotoxicity of
[Pd(L1)2] complex shows the promising results when analyzed using MTT cell proliferation assay.
Near White Emitting Host Sensitized Dy3+ doped GdPO4 Nanoparticles: Luminescence Studies
Authors: Chingangbam Elizabeth , Yaiphaba N. , Phaomei Ganngam
Published: October 2022

Host sensitized GdPO4 nanoparticles doped with Dy3+ ions have been prepared by co-precipitation
method with ethylene glycol as capping agent as well as solvent. The as-prepared samples exhibit
crystalline monoclinic phase of GdPO4. From the luminescence study, 4F9/2→6H15/2 of Dy3+ is dominant
over 4F9/2→6H13/2 transition indicating the occupation of inversion symmetry by Dy3+ ions in the host
lattice. The steady state luminescence shows effective energy transfer from gadolinium (Gd3+) to
dysprosium (Dy3+) ions in the doped samples with optimum emission of Dy3+ (2 at.%) doped sample.
Decay lifetime values also decrease upon increasing Dy3+ ion concentration on account of
cross-relaxation concentration quenching effect. The emission colour of single phase as-prepared Dy3+
doped GdPO4 nanoparticles can be tuned from blue-violet to near white light by changing the excitation
wavelength. Tunability of the light and white light emission are supported by Commission Internationale
de l’Eclairage (CIE) chromaticity.
Photoluminescence and Induction Heating Studies of Fe3O4@CaWO4:5Dy3+
Magnetic-Luminescent Nanocomposite for Hyperthermia Application
Authors: Khundrakpam N.S. , Singh L.P. , Ningombam G.S. , Singh N.R. , Srivastava S.K.
Published: October 2022

A 5 at.% Dy3+ ions doped CaWO4 nanoparticles (CaWO4:5Dy) were synthesized by hydrothermal
method using polyethylene glycol (PEG) as solvent medium and capping agent. The phase purity and
crystalline properties of the prepared nanoparticles were obtained from the XRD analysis. TEM images
revealed that the CaWO4:Dy3+ have particles of size approximately in the range 30-50 nm. The prepared
magnetic luminescence nanocomposite exhibits a high saturation magnetization. The prepared
nanocomposite can achieve hyperthermia temperature (42 ºC) in a short period by applying the
alternating magnetic field, externally. The nanocomposite also shows photoluminescence properties.
Nanomaterials described in this work can be used for optical imaging as well as hyperthermia
applications.
Evaluation of the National Influenza Sentinel Surveillance System in Tanzania, March 2021
Authors: Shedura Vulstan , Kamori Doreen , Mchau Geofrey , Willilo Ritha , Hussein Ally , Nyanga Salum
Published: October 2022

Background

Globally, seasonal epidemics are estimated to result about 3 to 5 million cases of severe illness, and about 290 000 to 650 000 respiratory deaths yearly. In order to facilitate early detection of Avian Influenza (AI), Tanzania through the Ministry of Health, Community Development, Gender, Elderly and Children (MoHCDGEC) initiated a sentinel surveillance system in 2008, for determining the disease burden and detect any new strain capable of causing pandemic.:
Objectives:To assess the usefulness of the system, its attributes as well as to ascertain if the system meets its objectives.

Methodology: Data were collected through
review of documents and interview of key stakeholders involved on the entire cascade of the system. Case definition (ILI and SARI), results and demographic characteristics of each patient were obtained from Laboratory Information System at National Influenza Laboratory (NIL). The system attributes were evaluated using Centre for disease prevention and control updated guidelines for evaluating public health surveillance system (2007)- Morbidity and Mortality Weekly Report (MMWR).

Results
: A total of 1731 samples were collected from influenza suspects in 2019 from sixteen sentinel sites where 52.7% were male. Laboratory confirmed cases were 21% (363/1731) with PVP of 21%. Most patients detected for influenza A; those presented with ILI symptoms were more likely to have influenza B than those with SARI. 55% met the TAT, 40% of case-based forms were incomplete filled, data consistency was poor with 23% discrepancy. Data accuracy was good with an average performance of 100%.

Conclusion and recommendations:
The System has met its objectives regarding that it is useful, sensitive, flexible, stable, well representative and able to generate accurate data by the average performance of 100%, which entails to a realistic estimation for the burden of influenza disease in the country.
Aquatic plant dynamic and fishes over the last 1800 years in the Lake Aiguebelette (Northern French Alps)
Authors: Giguet-covex Charline , Messager Erwan , Arthaud Florent , Gielly Ludovic , Jenny Jean-Philippe
Published: October 2022

Watersheds of large peri-alpine lakes have undergone substantial demographic and urban developments (leading to the release of waste waters, containing nitrates and phosphates), as well as agricultural activities intensification (use of fertilizers) during the 20th century. The seasonal fluctuations of their water levels is often reduced and controlled to generate hydroelectric power or to reduce flooded areas. Furthermore, these lakes host fishing activities, often for commercial purpose. These pressures, combined with global warming, significantly impacted the aquatic ecosystems especially through the eutrophication process and modifications of the trophic web.

In order to understand such limnological changes, several peri-alpine lakes are monitored for several decades. However, this instrumental monitoring does not allow the assessment of the ecosystem state before the anthropisation acceleration. Lake sediment cores represent relevant archives to fill this gap. Geochemical analyses and biotic remains preserved in lake sediments can be used to reconstruct the past long-term trajectories of aquatic ecosystems.

However, up to now, palaeoecological studies undertaken on lake sediments were only focused on phytoplankton, zooplankton, chironomids or microbial communities, but nor on aquatic plant community, nor on fishes. For fishes, this lack is explained by the absence (or rare presence) of fossils preserved in the sediments and for aquatic plants by a limited detection by pollen analyses. Environmental DNA preserved in the sediment offers a unique opportunity to address these challenges.

In this paper, the DNA metabarcoding approach is used to identify past aquatic plants and fishes living over the last 1800 years in the Lake Aiguebelette (390 m a.s.l., 5.45 km
2 lake surface area, 70 km
2catchment area, 73m deep). The most significant result is the evidence of interactions between aquatic plants and fishes. Roach, a fish species which has a preference for aquatic grass habitats, appears from 1000 years AD, i.e. when the diversity and biomass of aquatic plants highly increase. This change also corresponds to the development of mesotrophic conditions due to the intensification of the livestock farming.
O ENTORNO DA ESCOLA COMO TERRITÓRIO USADO: UMA ESCALA DE PLANEJAMENTO E AÇÃO
Authors: Braga Mariane Marcia Barros , Juliasz Paula Cristiane Strina
Published: October 2022

O presente artigo tem como objetivo resgatar o conceito de território usado (Santos, 1994; Santos e Silveira, 2001) para analisar a área denominada como entorno construída a partir da escola como centralidade e que possibilita uma nova escala de análise para o planejamento de políticas públicas voltadas aos estudantes adolescentes. Demonstrando assim, a falta de articulação entre o planejamento das políticas públicas e o entorno da escola o que fragiliza a formação cultural, humana e cognitiva dos adolescentes. Desse modo a escala de ação não acontece no nível do território do entorno, onde os agentes se deslocam e constroem relações dentro de suas rotinas, mas parte dos agentes externos retirando dos adolescentes e de toda a comunidade escolar o direito de construir políticas a partir de uma ação participativa e realmente capaz de transformar o território a partir de suas potencialidades.
MODELAGEM DA SUSCETIBILIDADE EROSIVA LAMINAR E LINEAR NO ENTORNO DE RESERVATÓRIOS DE USINAS HIDRELÉTRICAS
Authors: Romão Patrícia de Araújo , Nascimento Diego Tarley Ferreira , Sales Maurício Martines , Da Luz Marta Pereira
Published: October 2022

O processo erosivo hídrico natural ocorre em ritmo lento e a alteração antrópica altera essas condições de equilíbrio, intensificando o processo. Dentre as características que condicionam esse processo, destaca-se a suscetibilidade à erosão laminar e à linear nas bordas do reservatório da UHE de Itumbiara (GO/MG). Neste sentido, o objetivo geral da pesquisa é apresentar uma proposta de modelagem da suscetibilidade e da potencialidade erosiva hídrica, laminar e linear, em borda de reservatórios. Para atingir tal objetivo, além do cadastro das respectivas feições, foi realizado o processamento digital de modelos digitais de elevação e o mapeamento dos condicionantes físicos. Concluiu-se que, em geral, os processos erosivos coincidem com as classes moderadamente altas ou de média suscetibilidade. Quanto à potencialidade, ocorre o predomínio do uso agropastoril sobre alta ou moderadamente alta suscetibilidade, tanto para o processo erosivo laminar quanto para o linear.
GEOCULTURA: PROPOSTA TEÓRICO-METODOLÓGICA PARA O CONHECIMENTO, VALORIZAÇÃO E APLICAÇÃO DA GEOCONSERVAÇÃO
Authors: De Moura-Fé Marcelo Martins , Guimarães Thaís de Oliveira , Holanda Cristina Rodrigues , Do Nascimento Marcos Antônio Leite , Da Silva João Victor Mariano
Published: October 2022

A geodiversidade se notabiliza pela diversidade dos fatores que a compõem e por sua importância para a ocorrência e manutenção de processos naturais e ecossistêmicos fundamentais para vida no planeta Terra. Considerando os riscos socioeconômicos de degradação, é peremptória a necessidade de desenvolver projetos, atividades e ações geoconservacionistas. Nesse contexto, esse manuscrito tem como objetivo apresentar uma proposta teórico-metodológica da geocultura, conceito proposto para analisar a influência da geodiversidade sobre as manifestações culturais, materiais ou imateriais, as implicações associadas e suas possíveis aplicabilidades; um conceito voltado para o conhecimento, valorização e aplicação da geoconservação. Metodologicamente, a pesquisa fundamentou-se em uma abordagem qualitativa, com fins descritivos, segmentada em um criterioso e sistematizado levantamento bibliográfico, análises do arcabouço teórico e levantamentos de campo. Como resultados são apresentadas e problematizadas conceituações pertinentes, parâmetros, pressupostos e bases da geocultura, com a análise de formas teóricas e práticas de desenvolvimento e aplicação; bem como o detalhamento e a explicação das etapas do roteiro teórico-metodológico. Espera-se que essa proposta se apresente como uma estratégia geoconservacionista eficaz, que potencialize o escopo presente nas bases (geo)culturais utilizadas, direcionando-as para as especificidades e necessidades da geodiversidade; tendo seu roteiro usado, melhorado e consolidado por meio de sua aplicação.
DETERMINAÇÃO DA COBERTURA VEGETAL DE OLINDA, PERNAMBUCO - BRASIL: UM SUBSÍDIO À GESTÃO FLORESTAL URBANA
Authors: Lopes Iran Jorge Corrêa , Lima Neto Everaldo , Pessoa Mayara Maria de Lima , Reis Allan Rodrigo Nunho dos , Ribas Eduardo Campanhã , Silva Anderson Francisco da , Pereira de Oliveira Cinthia , Santos Nattan Ádler Tavares dos
Published: October 2022

A expansão urbana sem planejamento adequado promoveu uma série de efeitos nocivos para a população das cidades, tanto ambiental quanto socialmente. Contudo, cada vez mais a vegetação vem sendo associada à qualidade de vida, devido aos comprovados benefícios que ela promove no ambiente urbano. Esta pesquisa objetivou classificar a cobertura vegetal de Olinda - Pernambuco, visando a quantificar sua floresta urbana. Para isso, utilizou-se uma imagem do satélite SENTINEL-2 com resolução espacial de 10 metros, para a classificação do uso do solo do município. Por meio do software QGIS 2.14.11, identificaram-se as classes de infraestrutura urbana, água, solo exposto, vegetação e nuvem, por meio da classificação supervisionada MaxVer, posteriormente divididas por regiões político administrativas para o mapeamento, sendo assim determinados e quantificados os índices de cobertura vegetal da cidade. A quantidade de vegetação nas regiões se mostrou variável, mas foram insatisfatórias para promover benefícios ambientais à população, com exceção da Zona Rural, local onde há maior quantitativo de vegetação da cidade. Observou-se que Olinda é uma cidade com déficit de cobertura vegetal, sendo possível perceber que o município carece de áreas vegetadas, bem como arborização.
ESPACIALIDADE DA VIOLÊNCIA CONTRA AS MULHERES NO MUNICÍPIO BRASILEIRO DE ILHÉUS
Authors: Loureiro Elisabeth Zorgetz , Benfica Nayanne Silva , Gomes Andréa da Silva , Almeida Yuri Nascimento
Published: October 2022

Este artigo explora as características espaciais, temporais e raciais da violência contra as mulheres captadas pela Delegacia Especial de Atendimento à Mulher no município de Ilhéus, localizado no nordeste do Brasil. O objetivo deste estudo foi traçar um perfil da violência contra as mulheres no município de Ilhéus norteado pelo interesse em conhecer a distribuição espacial das notificações da Delegacia Especial de Atendimento à Mulher (DEAM). O trabalho se baseou em estatística descritiva e utilizou geoprocessamento para mapear o local de ocorrência de violência contra as mulheres denunciantes nos anos 2013 e 2018 e foram analisadas 2268 denúncias. Os resultados demonstraram que os casos mais incidentes registrados fixam-se nos crimes de ameaça e lesão corporal, somando mais de 90% das notificações, tendo como principais vítimas mulheres autoconsideradas pardas, na faixa etária entre 25 a 29 anos no ano de 2013 e entre 35 e 64 anos no ano 2018. Também foi constatado que as ocorrências são mais comuns nos finais de semana, especialmente no domingo, entre o horário das 17hrs às 20hrs. Além disso, os resultados fornecem indicativos sobre o vínculo entre as áreas de pobreza e violência de gênero.
IDENTIFICAÇÃO E DETERMINAÇÃO DA ALTURA DAS ÁRVORES DE EUCALYPTUS SP A PARTIR DE DADOS LIDAR E AVALIAÇÃO DOS RESULTADOS POR MEIO DE ORTOFOTOS E MEDIDAS DE CAMPO
Authors: Lage Gustavo Bretas , Oliveira Kelen Karla Reis , Bretas Lage Tulio , Nero Marcelo Antonio , Alexandrino Garcia Ricardo
Published: October 2022

Este trabalho teve como objetivo estimar a posição geográfica e a altura individual de árvores em plantios de eucalipto de modo automatizado por meio de processamento computacional. Os dados utilizados nesta pesquisa foram obtidos com o sistema Airborne Laser Scanner (ALS) e permitiram gerar um modelo digital de vegetação normalizado (MDVn) que representa a biomassa da superfície. Nesse modelo, aplicou-se uma metodologia de geoprocessamento que permitiu analisar o modelo da biomassa, determinando-se o topo de cada árvore e sua altura. Para validar os resultados, utilizaram-se ortofotos de melhor resolução espacial disponível, obtendo-se 93% de precisão média nos cálculos. Na comparação dos dados de alturas médias estimadas das 100 maiores árvores por meio da tecnologia LIDAR e das mesmas alturas obtidas por meio do inventário florestal, o coeficiente de determinação R² foi de 0,8826. Os resultados indicaram que a metodologia utilizada apresenta precisão adequada para a identificação de indivíduos e para a estimativa de altura das árvores, oferecendo viabilidade de replicação da metodologia para outros tipos de vegetação similares.
IMPACTOS DA SECA SOBRE A CULTURA DO CAJU NO SEMIÁRIDO BRASILEIRO NO INTERSTÍCIO DE 2012 A 2017
Authors: Da Silva Manoel Mariano Neto , De Brito Higor Costa , Freitas Carla Camila Gomes , De Brito Yáscara Maia Araújo , Da Silva Janaína Barbosa
Published: October 2022

O artigo objetivou analisar impactos da seca plurianual 2012-2017 sobre a cultura do caju, no município de Severiano Melo, Rio Grande do Norte, a partir de sensoriamento remoto e da percepção ambiental dos agricultores. Para tanto, foram estudados os aspectos hidrológicos referentes à precipitação pluviométrica. Posteriormente, foram realizadas análises espaciais, mediante pesquisa de campo e emprego do Índice de Vegetação Ajustado ao Solo (SAVI), através de imagens dos satélites Landsat 7 e Landsat 8. Aplicou-se ainda um questionário semiestruturado a 19 agricultores. Constatou-se a ocorrência de mudanças de cobertura do solo, devido à redução do vigor da vegetação; e redução da disponibilidade hídrica superficial. A cultura do caju registrou perdas de área plantada, decorrentes do estresse hídrico; incidência de pragas; e doenças agrícolas. Infere-se que a mortalidade dos cajueiros pode ter contribuído para redução dos valores de SAVI e dificuldades de recuperação do vigor vegetal, após o término da estiagem. Logo, a produção da castanha foi severamente afetada em virtude da escassez de chuvas, afetando a renda dos agricultores. Em busca da reestruturação da cajucultura na região, o replantio dos pomares teve início em 2014, em meio às adversidades da escassez hídrica e à ausência de suporte especializado.
PAISAGEM URBANA E O SENTIDO DA REPRESENTAÇÃO FOTOGRÁFICA: A BUSCA DA MODERNIDADE NA UBERLÂNDIA DA DÉCADA DE 1950-1960
Authors: Viso Guilherme Alves , Canas Adriano Tomitão , Soares Beatriz Ribeiro
Published: October 2022

A utilização do instrumento fotográfico é uma ferramenta auxiliar que complementa e dá suporte em uma pesquisa na obtenção de resultados, sendo assim, em sua maioria, um elemento secundário em todo o processo de pesquisa. Contudo, este artigo traz uma inversão na utilização da fotografia, trazendo-a como objeto de análise central para compreendermos a formação da paisagem urbana da cidade de Uberlândia, Minas Gerais, das décadas de 1950 e 1960. O texto, após expor reflexões teóricas sobre a paisagem urbana e fotografia, reflete sobre o material fotográfico coletado e a sua implicação na representação da cidade e sua busca pela modernidade.