bluuebunny/crossref_metadata_2025 huggingface dataset:
Legal regulation of the transmission of health-related data: Balance of public interests and individual rights in the context of cross-border health care
Authors:   St. Petersburg State University, Akulin Igor M. , Chesnokova Ekaterina A. ,   St. Petersburg State University, Genovese Umberto ,   University of Milan, Presnyakov Roman A. ,   Association of Medical Law of St. Petersburg, Pryadko Anastasia E. ,   Committee for Social Protection of the Population of the Leningrad Region
Published: August 2021

The article provides a comparative analysis of the regulatory and legal regulation for the processing of a special category of personal health data in the European Union and in the Russian Federation in regard to the digitalization of national health systems. Special attention is paid to the legal framework for the transmission of health information at the cross-border level. It is established that within the framework of European and Russian legislation at this stage, in the context of the formation of digital medicine, there is a comparability in the definition of legal mechanisms for the protection of medical data. It is also noted that in the issue of the transfer of personal health data to third countries, both the Russian Federation and the European Union choose the path of strict restrictive regulation and the introduction of a closed list of grounds for overcoming the ban on cross-border transfer. The reasons for this approach to issues of supranational interaction in healthcare are analyzed, as well as the potential risks of inertia of national legislators in this issue. Based on the analysis, the authors propose a number of amendments and additions to the national legislation on personal data, aimed at simplifying the interaction between jurisdictions on the transfer of confidential medical information. The authors suggest an international agreement on the exchange of medical data in digital format, which potentially should include not only the Russian Federation and the EU states, but also other countries, including Eurasian Economic Union member states, China, and countries of the American continent. The proposed concept is intended to create an opportunity for the formation of a supranational information system in the field of healthcare, which allows for the effective exchange of medical data, taking into account the sovereign interests of the countries participating in the agreement.
Emotional Intelligence, Big Five Traits and Emotional Creativity in latent personality profiles
Authors:   Lomonosov Moscow State University, Kornilova Tatiana , Shestova Mariia ,   Lomonosov Moscow State University, Kornilov Sergey ,   Institute for Systems Biology
Published: August 2021

Studies in the last decade that examined the relationship among the traits that form a personality profile, identified both the relationship between emotional intelligence and the Big Five traits or focused on arbitrarily identified mediators and moderators in the system of measured traits. However, our current understanding of the associations between Big Five traits and emotional creativity (a trait related to emotional intelligence) is lacking. Thus, the objective of the study was to identify latent profiles which represented homogenous subgroups of individuals based on measured personality traits; and to compare the results from a variablecentered approach and the person-centered approach (latent profile or class analysis). Design: a total of 527 students participated in the study (395 women and 135 men, Min 17, Max 43, M=19.2, SD=2.9), 402 were administered the complete assessment battery. The latter included 1) the Ten Item Personality Measure (TIPI), 2) the Trait Emotional Intelligent Questionnaire (TEIQ), 3) and the Emotional Creativity Inventory (ECI). The study shows that the traits of the Big Five as expected were positively associated with all the subscales of emotional intelligence. The analysis of latent profiles identified 4 distinct classes that do not appear when correlation analysis was used in a variable-centered analysis. Specifically, it was the properties of emotional intelligence that were the main group of discriminating variables when establishing personal profiles. Among the Big Five traits, Emotional Stability and, among the all emotional creativity components, Efficiency were the strongest discriminating factors; the maximum contribution to the identification of personal profiles was made by the traits of emotional intelligence.
Features of parent-child interaction and behavioral problems among children with autism spectrum disorder
Authors:   St. Petersburg State University, Pleshkova Natalia , Tatarenko Oksana ,   Center of Psychological Intervention for Children, Sevryugin Denis ,   Stavropol Clinical Psychiatric Hospital N 1
Published: August 2021

The article presents the results of a study of behavioral features of children with autism spectrum disorder (ASD) in connection to the characteristics of psychological interaction of children and their mothers. It previously has been found that children with ASD demonstrate more communicative and social activity, have less pronounced symptoms of autism, if their parents show a high level of sensitivity to the needs of children and are emotionally involved in interaction with them. The study’s participants consisted of 29 children with ASD (average age: 52,4 ± 8,9 months) who were diagnosed by a psychiatrist during examination in the Stavropol Clinical Psychiatric Hospital no. 1. The comparison group included 36 typically developing children (average age: 39,7 ± 12,1 months). The PCERA method, with a video recording of mother — child interactions, was used for assessing qualities of interaction in children with ASD. Behavioral difficulties were evaluated using the CBCL/1.5-5 questionnaire. The results of the study suggest that low sensitivity to child’s cues, high intrusiveness and negative affect in mothers, and low level of reciprocity and enjoyment in the dyadic relationship are linked to borderline/clinical levels on several DSM-oriented scales (“Affective Disorders”, “Pervasive Developmental Problems”, “Oppositional Defiant Problems”) and syndrome scales (“Emotionally Reactive”, “Anxious/Depressed”, “Aggressive Behavior”) in children with ASD.
Personal projects of young Russians and Spaniards: A comparative analysis
Authors:   Financial University under the Government of the Russian Federation, Кlementyeva Marina , Ryazantseva Ekaterina ,   Tula State University
Published: August 2021

This article aims to clarify the personal projects of Russians and Spaniards. It was hypothesized that the content and methods for the implementation of personal projects are determined by the main age-related tasks and cultural conditions of life. The sample of convenience consisted of young Russian (n = 102) and Spanish (n = 80) people between the ages of 18–25 years. The study focused on aspects, which were measured: importance, difficulty, visibility, control, responsibility, time adequacy, likelihood of success, self-identification, the view of others, value, involvement, competence, autonomy and duration of personal projects, and theme and transperspective of projects. The results indicated that the goal of the personal projects of young Russians and Spaniards is similar (getting an education, employment, creating a family and supporting family relations) and is determined by the main age-related tasks of youth. Furthermore, the operational meanings of personal projects and the ways of their implementation have cultural differences. The authors found that young Spaniards orient their personal projects towards opportunistic meanings and the current pandemic (COVID-19) more than in Russians (р ≤ 0.03). Furthermore, Russians choose personal projects that correspond to instrumental values in the long term more than in Spaniards (р ≤ 0.03). The level of difficulty, importance, initiative, responsibility, autonomy, self-realization, positive assessment of others in personal projects of Russians was higher than in personal projects of Spaniards (р ≤ 0.003). There was a higher level of internal resources in personal projects of Spaniards, than in personal projects of Russians (р ≤ 0.05). Therefore, a personal project of modern young people is a delayed solution to the age-related tasks of youth, and the ways of solving them are determined by the socio-cultural conditions of life.
Development of multivariate integrated drought monitoring index (MIDMI) for Warangal region of Telangana, India
Authors: Tapas Mahesh R. , Kumar Uday , Mogili Sudhakar , Jayakumar K. V.
Published: August 2021

Agricultural drought is one of the most frequent natural disasters in India's southern part. Remote sensing-based drought indices give advantages in terms of continuous monitoring of land surface. The crop production in the Warangal region in India's southern part is adversely affected due to insufficient rainfall and poor irrigation management. This study aims to develop a multivariate remote sensing-based composite drought index (CDI) to monitor the agricultural drought. Landsat-8 satellite data for all the 11 subregions of Warangal urban and 15 subregions of the rural district of Telangana from 2013 to 2020 for the month of May is used to obtain drought indices. The drought indices are used in this study to develop MIDMI and are compared according to the percentage area of the Warangal region under five different drought categories. In this study, the MIDMI is computed by a weighted average of five vegetation drought indices for the Warangal region as per the method developed by Iyengar and Sudarshan for the multivariate data. MIDMI for all the 26 subregions of the Warangal rural and Warangal urban districts is between 0.4 and 0.6, which makes the Warangal region moderately vulnerable to agricultural drought.
Effects of algae and hydrophytes on the inorganic phosphorus pool of shallow hypereutrophic Lake Taihu
Authors: Li Xiaojun , Xu Xiaoguang , Zhao Yanping , Han Ruiming , Wang Guoxiang
Published: August 2021

Sedimentary phosphorus is a crucial potential source of phosphorus in the eutrophic lake ecosystem. Different ecological types are supposed to affect the presence and variation of sediment phosphorus. On the basis of field investigations, the total sediment phosphorus load in Zhushan Bay was 1,457.48 mg/kg, nearly four times that of the hydrophyte-dominated area. Thereinto, 41.1% was in the form of iron and aluminum-bound phosphorus, which explicitly indicated the phosphorus contamination there. Analytical methods such as Pearson correlation, contamination assessment and principal component analysis were conducted to find out that ‘contamination’ was not equivalent to ‘release risk’. The contamination classification of East Lake Taihu was ‘clean’ in general. However, 63.3% of the total phosphorus could be mobilized under certain conditions. Therefore, light phosphorus loading does not equate to less release risk. In the long run, the implicit phosphorus release by the activation of organic phosphorus in hydrophytic areas needs close attention. This study provides a reference to understand the influence of hydrophytes and algae on the phosphorus cycle of sediment.
GABAB Receptors: are they Missing in Action in Focal Epilepsy Research?
Authors: Avoli Massimo , Lévesque Maxime
Published: August 2021

:

GABA, the key inhibitory neurotransmitter in the adult forebrain, activates pre- and
postsynaptic receptors that have been categorized as GABAA, which directly open ligand-gated (or
receptor-operated) ion-channels, and GABAB, which are metabotropic since they operate through
second messengers. Over the last three decades, several studies have addressed the role of GABAB
receptors in the pathophysiology of generalized and focal epileptic disorders. Here, we will address
their involvement in focal epileptic disorders by mainly reviewing in vitro studies that have shown:
(i) how either enhancing or decreasing GABAB receptor function can favour epileptiform synchronization
and thus ictogenesis, although with different features; (ii) the surprising ability of GABAB receptor
antagonism to disclose ictal-like activity when the excitatory ionotropic transmission is abolished;
and (iii) their contribution to controlling seizure-like discharges during repetitive electrical
stimuli delivered in limbic structures. In spite of this evidence, the role of GABAB receptor function
in focal epileptic disorders has been attracting less interest when compared to the numerous studies
that have addressed GABAA receptor signaling. Therefore, the main aim of our mini-review is to revive
interest in the function of GABAB receptors in focal epilepsy research.
Features of the Course of COVID-19 in Health Care Workers of a Non-infectious
Hospital
Authors: Leonova Marina , Gaisenok Oleg
Published: August 2021

Background:

Health Care Workers (HCWs) are at high risk of SARS-COV-2 infection
and COVID-19 disease, not only in the chain of care for COVID-19 patients but also in non-infectious
health care organizations that provide routine medical care to the population.

Objective:

To analyze features of the course of COVID-19 in HCWs of a non-infectious hospital
(non-IH).

Methods and Materials:

A retrospective analysis of COVID-19 cases of HCWs of a non-infectious
hospital (non-IH) due to a local outbreak during the “second wave” of the pandemic, despite the
use of PPE.

Results:

7 HCWs out of 23 employees were infected and had a confirmed COVID-19 infection.
All pointed to the presence of contact at work (patients, colleagues) as the main possible contamination
factor. The development of COVID-pneumonia was observed in 4 persons; 2 of them were hospitalized.
The most common symptoms were fever with a maximum temperature rise of 37.8-39
°C, weakness, chest pain, cough, and loss of smell. The duration of the persistence of symptoms of
the disease was up to 16 days. The elimination of coronavirus in most patients was noted after the
10th day.

Conclusion:

HCWs in non-IH providing routine medical care are at increased risk of contracting
COVID-19 due to contact with infected patients or colleagues. The development of COVID-19 disease
in HCWs leads to long-term disability, which creates tension in the work of non-IH. To reduce
the risk of infection for non-IH HCWs, stated precautions are necessary: strict adherence to
PPE use, mandatory testing of SARS-COV-2, and planning observational wards for unexamined
patients hospitalized for medical care for other indications.
MRI Features and Clinical Significance of Spinal Epidural Lipomatosis: All You Should Know
Authors: Spinnato Paolo , Barakat Massimo , Lotrecchiano Ludovica , Giusti Davide , Filonzi Giacomo , Spinelli Daniele , Pipola Valerio , Moio Antonio , Tetta Cecilia , Ponti Federico
Published: August 2021

:

Spinal epidural lipomatosis (SEL) is defined as the abnormal accumulation of unencapsulated adipose tissue in the spinal epidural space. SEL can be asymptomatic or can cause a wide range of symptoms, the most common of which is neurogenic claudication. Several other neurological manifestations may also occur, above all myelopathy and radicular symptoms. The spinal level most frequently involved in patients with SEL is the lumbar one, followed by the thoracic one.
Imaging plays a key role in disease assessment. MRI is considered the most effective and sensitive modality for diagnosing and staging SEL. Anyway, also CT scan can diagnose SEL. The diagnosis may be incidental (in mild-moderate disease) or may be taken into account in cases with neurological symptoms (in moderate-severe disease).
There are some recognized risk factors for SEL, the most common of which are exogenous steroid use and obesity. Recent studies have found an association between SEL and obesity, hyperlipidemia and liver fat deposition. As a matter of fact, SEL can be considered the spinal hallmark of metabolic syndrome.
Risk factors control represents the initial treatment strategy in patients with SEL (e.g. weight loss, steroid therapy suspension). Surgical decompression may be required when conservative treatment fails or when the patient develops acute/severe neurological symptoms.
NMR-based Metabolomic Techniques Identify the Anticancer Effects of Three Polyphyllins in HepG2 Cells
Authors: Su Feng , Su Weike , Wang Haibo , Wang Yifan , Ye Lv , Zhu Peixi , Gu Jinping
Published: August 2021

Background:

Rhizoma Paridis (RP) is a traditional Chinese herb used for the treatment of tumors, detoxification and hemostasia. Studies show the main components of RP are Polyphyllin I (PPI), polyphyllin VI (PPVI), and polyphyllin VII (PPVII). However, the pharmaco-mechanisms of these compounds are not clear.

Objective:

By used 1H nuclear magnetic resonance (1H-NMR) based metabolomics approach to identify the Anticancer effects of PPI, PPVI and PPVII in HepG2 cells.

Methods:

1H nuclear magnetic resonance (1H-NMR) based metabolomics approach was applied to investigate the toxicological effect of PPI, PPVI, PPVII on HepG2 cells. Multivariate statistical analysis was employed to examine the metabolic changes and abnormal metabolic pathways, including Principal Component Analysis (PCA), Partial Least Squares Discriminant Analysis (PLS-DA), and orthogonal PLS-DA (OPLS-DA).

Results:

The results showed that the effects of metabolic phenotypes were affected separately by PPI, PPVI, and PPVII. The metabolic phenotypes were also changed over time. The characteristic metabolites were varied by affecting different polyphylins, which were identified by the reconstructed OPLSDA loading plots. According to the characteristic metabolites, the mainly disturbed metabolic pathways were found, such as alanine, aspartate and glutamate metabolism, pyruvate metabolism, glycine, serine, and threonine metabolism.

Conclusion:

The current work could allow us to understand the therapeutic effect of RP in metabolism. It also indicated that RP would be a promising candidate for liver cancer treatment.
Evidence-based Recommendations on Periodontal Practice and the Management of Periodontal Patients During and After the COVID-19 Era: Challenging Infectious Diseases Spread by Airborne Transmission
Authors: Di Spirito Federica , Iacono Vincent J , Alfredo Iandolo , Alessandra Amato , Sbordone Ludovico , Lanza Antonio
Published: August 2021

Background:

Periodontal care, which was completely suspended during the peak of the SARS-Cov-2 pandemic and was delayed and recurrently discontinued during the succeeding waves, must be safely provided in the COVID-19 era.

Objectives:

The study aimed to provide recommendations on periodontal practice, optimizing safety, ergonomics, and economic resources, and the management of periodontal patients, ensuring continuity, timing, and effectiveness of periodontal care in the COVID-19 era.

Methods:

Reported protocols for the dental practice in the context of the COVID-19 and current evidence on periodontitis treatment and prevention were reviewed.

Results:

Evidence-based recommendations on contamination control and ergonomic improvements for periodontal practice and the management of periodontal patients challenging COVID-19 and airborne infectious diseases have been provided.

Conclusion:

Due to the economic, ergonomic, and ethical concerns raised by limited periodontal care due to the SARS-Cov-2 pandemic, and awareness of other emerging airborne transmitted infections, the periodontal practice should integrate measures minimizing airborne cross-infections and optimizing time-space and economic resources. The management of periodontal patients in the COVID-19 era should comprise less complex treatments and more comprehensive and definitive approaches, reducing emergencies, session length and number, and, concurrently, extending the recall and maintenance intervals. Moreover, it should implement prevention strategies through teledentistry tools and apps, improving periodontal awareness and self-care, and also through the self-reporting of periodontitis and periodontal risk assessment tools, performing both “population-based” and “high-risk” surveillance of periodontitis. Finally, it should enhance inter-professional collaboration, through telehealth networks, especially targeting subjects at high-risk of both periodontitis and systemic disorders, each of the two variously linked to COVID-19 onset and worsening.
Urinary Retention Secondary to Colpocleisis: A Case Report
Authors: Soto-Vega Elena , Cuan-Baltazar Yunam , García-Mora Arturo , Arroyo Carlos
Published: August 2021

Introduction:

Pelvic Organ Prolapse (POP) is common in older women, and depending on its extent, it is conservative or surgically treated. Colpocleisis is a technique for POP treatment, in which the vaginal canal is closed, entirely or partially, in order to avoid the protrusion of the pelvic structures, with preservation of the urethral meatus in order to preserve normal micturition.

Clinical Case:

We present a case of a 61-year old woman, who 8 years after a colpocleisis, progressed to urinary retention associated with the progressive scarring of the labia, causing the obstruction of the urethral meatus. The patient underwent a labiaplasty with anterior colpoperineoplasty, with complete normalization of her micturition and sexual activity.

Conclusion:

Long term urinary retention complication has not been previously reported in the literature and should be included as a possible adverse event after colpocleisis.
Traumatic Heel Pad Avulsion in a Pediatric Patient
Authors: Kelly Joseph P. , Catoe Benjamin , Khan Mudassar , Antekeier David P.
Published: August 2021

Introduction:

Heel pad injuries can have devastating and debilitating consequences. All efforts to primarily reapproximate the heel pad should be undertaken. Reconstruction of the heel pad can often require multiple complex surgeries including microvascular flaps and tissue transfers. There is a paucity of successful techniques for primary repair in the literature.

Case Presentation:

In this case report, we describe the successful use of polydioxanone suture with sterile buttons for the repair of the heel pad in a pediatric patient. An 8-year-old male was struck by a vehicle, sustaining a full-thickness heel pad avulsion injury measuring approximately 16-cm in length. The soft tissue was sharply debrided and repaired primarily to the calcaneal periosteum using #1 polydioxanone suture with external suture buttons, and an incisional wound VAC was applied. He was placed into a long-leg bent knee cast and kept non-weight bearing for a total of 6 weeks, at which time the suture and buttons were removed and he was progressed to weight bearing as tolerated in a walking boot. At the 6-month follow-up examination, the heel pad was viable and well-fixed; the patient reported no pain and was not limited in any chosen activities.

Conclusion:

This construct was shown to provide effective fixation while mitigating reported concerns of tissue necrosis caused by suture repair. At 1 year from injury, the patient’s mother noted a slight limp with running but not with walking. He reported no pain at any time, and his Oxford Ankle-Foot Questionnaire for Children score was 58, indicating excellent patient-reported outcome following his procedures.
Neurovascular Compression in Arterial Hypertension: Correlation of Clinical Data to 3D-Visualizations of MRI-Findings
Authors: Manava Panagiota , Hastreiter Peter , Schmieder Roland E. , Jung Susanne , Fahlbusch Rudolf , Dörfler Arnd , Lell Michael M. , Buchfelder Michael , Naraghi Ramin
Published: August 2021

Aims:

In this study, we attempted to identify clinical parameters predicting the absence or presence of Neurovascular Compression (NVC) at the Ventrolateral Medulla (VLM) in arterial hypertension (HTN) in MRI findings.

Background:

Cardiovascular and pulmonary afferences are transmitted through the left vagus and glossopharyngeal nerve to the brain stem and vasoactive centers. Evidence supports the association between HTN and NVC at the left VLM. Several independent studies indicate a reduction of HTN after Microvascular Decompression (MVD) of the left. Several independent studies indicate a reduction of HTN after Microvascular Decompression (MVD) of the left VLM. Image processing of MRI provides comprehensible detection of NVC. HTN affects hemodynamic parameters and organs.

Objective:

This study analyzes and correlates clinical data and MRI findings in patients with and without NVC at the VLM in treatment resistant HTN to obtain possible selection criteria for neurogenic hypertension.

Methods:

In 44 patients with treatment resistant HTN, we compared MRI findings of neurovascular imaging to demographic, clinical and lifestyle data, office and 24-hour ambulatory Blood Pressure (BP), and cardiovascular imaging and parameters.

Results:

Twenty-nine (66%) patients had evidence of NVC at the VLM in MRI. Sixteen patients (36%) had unilateral NVC on the left side, 7 (16%) unilateral right and 6 (14%) bilateral NVC. Fifteen (34%) had no evidence of NVC at the VLM. Patients with left sided NVC were significantly younger, than those without NVC (p=0.034). They showed a statistically significant variance in daytime (p=0.020) and nighttime diastolic BP (p<0.001) as the mean arterial pressure (p=0.020). Other measured parameters did not show significant differences between the two groups.

Conclusion:

We suggest to examine young adults with treatment resistant HTN for the presence of NVC at VLM, before signs of permanent organ damage appear. Clinical and hemodynamic parameters did not emerge as selection criteria to predict NVC. MVD as a surgical treatment of NVC in HTN is not routine yet as a surgical treatment of NVC in HTN is not routine yet. Detection of NVC by imaging and image processing remains the only criteria to suggest MVD, which should be indicated on an individual decision.
Relation between Social Gender Role Attitudes of Students Studying at Faculty of Health Sciences and States of Experiencing Peer Pressure
Authors: ALTIN Alaattin , AYDIN AVCI İlknur
Published: August 2021

Objectives: This research was carried out to determine the relationship between social gender role attitudes of students studying at Ondokuz Mayıs University, Faculty of Health Sciences and peer pressure situations. Materials and Methods: This study, performed in accordance with the descriptive research principles seeking a relationship was conducted with a total of 1115 students (82.6% of the target population of the study) studying at Samsun Ondokuz Mayıs University, Faculty of Health Sciences in the fall semester of the 2016-2017 academic year. "Presentation form", "Gender Roles Attitude Scale" and "Peer Print Scale" as data collection tools were used. While research data was being evaluated, number, percentage and Ki-Square (X²) test, Kruskal Wallis (KW) and Mann Whitney U tests were used. Findings: The total median of the students' gender role attitudes scale was 115 (min-max = 34-158) and the students had an egalitarian attitude. The peer scale had a median of 42 (min-max=33-167). There was not a meaningful relationship between students' gender role attitudes and peer pressure status (r=0,007; p>0,05) statistically. The peer pressure scale and the egalitarian gender role were negatively correlated (r = -0,068; p <0.05), the male gender role was positively correlated and hence it was found that there was a significantly weak level (r = 0.202; p <0.001). Conclusion: It was found that students have an egalitarian attitude towards gender roles, and the peer pressure on students is low. It may be suggested to add these subjects to the education curriculum to give university students an egalitarian gender attitude and to raise awareness about peer pressure.
Identification of Sago-Pulp Amylolytic Bacteria and Its Utilization for Granulated Fertilizer
Authors:   Universitas Brawijaya, Hasanah Uswatun , Ardyati Tri , Siswanto Dian
Published: August 2021

Previous research stated that bacteria isolated from sago waste from the traditional sago industry in Palopo had the potency to produce amylase. This study aims to confirm the ability of bacteria isolated from sago pulp waste to produce amylase, evaluate the ability of these amylolytic bacteria to produce IAA fix nitrogen, identify selected bacteria, and apply selected bacteria into granules biofertilizers. Bacteria were isolated from sago pulp waste and grown on a 1% starch agar medium. The amylolytic activity was analyzed qualitatively using iodine and quantitatively using the 3,5-Dinitrosalicylic Acid (DNS) method at pH 6. Amylolytic bacteria were analyzed for IAA production using Salkowsky reagent and nitrogen fixation ability through the Serra Kit method. Potential bacteria were identified based on the similarity of the 16S rDNA sequence. The selected bacteria were grown in a 10mL NB medium, and then bacteria were inoculated and air-dried to obtain the granules. The selected bacteria were put into granules and re-isolated using the total plate count (TPC) method. Eight amylolytic bacteria were obtained from sago pulp waste. L1E isolate had the highest amylolytic activity of 1.228 U.mL-1, and L1D isolate had the highest IAA production of 69.8 g.mL-1. Isolate L1E was identified as Alcaligenes faecalis with a 99.45% similarity index, and L1D was identified as Serratia surfactantfaciens with a 99.09% similarity index. Isolate L2G was identified as Alcaligenes aquatilis with a similarity index of 99.8% of the 16S rDNA sequence. The viability of bacteria from granules was 1.41 x 108 CFU.g-1. Keywords: Amylase enzyme, amylolytic bacteria, granulated fertilizer.
A Study on Promotion of Alcoholic Beverages
Authors: Pooja Narang  , Ritesh Dwivedi
Published: August 2021

India is one of the leading countries in consuming and manufacturing alcoholic beverages in the last few years. Alcohol is one of the major players in contributing an important role in India’s economy. Individuals are aware of the fact that advertisement of tobacco, cigarettes, and alcohol is banned in our country, but the leverage has been granted of promoting the brand through surrogate marketing. There are many traditional methods that are still successful in the promotion of alcohol like hoardings and banner, but some modern ways are promotion through social media, ladies’ night, etc. This study aims to explore the various promotional practices performed by alcohol companies and analyze the customer attitude towards it. A questionnaire survey was used to collect the customers’ primary data by visiting various clubs and bars. The total number of questionnaires that were analyzed is 200 using Statistical Package for the Social Sciences (SPSS). The result of SPSS was reviewed based on the hypothesis formed and the relationship is determined between various variables. With the help of results, we connected it to a research model related to consumer attitude. This study concluded that promotional activities play an important role and mostly impact brand awareness. Despite surrogate marketing, the entire liquor bran
Indian Pharma—Some Challenges and Acceptances
Authors: Sajna T
Published: August 2021

Business enterprises are an important organ of society. The impact of a business enterprise’s motive will directly affect society, which includes environment, consumers, employees, suppliers, and other stakeholders. Big pharma companies face a huge drop in revenue from blockbuster drugs coming off patent. Without generating revenues through sales, these companies will struggle to fund the development of new life-saving drugs. Artificial intelligence (AI) can be a powerful tool in the pharmaceutical industry’s research and development. So with the help of modern technologies, pharmaceutical companies should aim for quality but cheap products for common people and serve society better.
The Glittering Portfolio – A Study with Special Reference to Performance of Gold Investments
Authors: R Uppily , Ramaratnam M S
Published: August 2021

Gold has been one of the traditional and essential forms of asset in India; even today, gold ornaments are considered one of thenecessary investment forms as they can be pledged or converted into cash when there is a financial crunch. Gold investments in electronicformat have become popular in India from 2002 onwards. Investors always get confused on whether they should have gold in theirportfolio and whether they should have it in physical form or electronic form. Prices of gold have been fluctuating based on demand andsupply. This case study tries to analyze whether gold should be part of an investment portfolio
Impact of Second wave of COVID-19 Pandemic on the Consumption Pattern of Urban Consumers
Authors: Singh Abhishek Kumar
Published: August 2021

in India. The lockdown has disrupted the consumption habits of consumers. The study was conducted to assess the impact of the secondwave of COVID-19 on consumption patterns of consumers residing in urban areas of Varanasi and nearby towns.Methods: The required data were collected through an online survey. The questionnaire to assess the impact of the pandemic onconsumption patterns was sent to urban consumers of Varanasi and nearby towns using google forms. In addition, some of the consumer'sresponses were recorded using telephonic interviews. The data collected was analyzed through MS-Excel and Jamovi version 1.6.23software.Results/ Findings: It was found that the current pandemic has a significant impact on consumption patterns. The study reveals that mostrespondents' spending habits have changed; most spending is on essential items. In addition, consumers have adopted new practices likemany of them have started online purchasing, etc.Limitations: Due to administrative restrictions and social distancing mandates, a small sample was selected for the study. The study hastaken only urban consumers as a sample.Managerial Implications: The findings will help marketers search and implement new ways to survive and succeed in a pandemicsituation
Business Process Reengineering – A Review on Change Management
Authors: Singh Prashant , Kataria Pushpa
Published: August 2021

With today's highly competitive and rapidly changing world economic marketplace, firms must adopt business process reengineering tosustain their competitive advantages and increase profitability. BPR is one of the most popular ongoing change management theories as asolution for firms to improve their performance significantly, upraise their efficiencies, and gain a competitive advantage in thisconstantly developing and changing world. BPR usually leads to essential organizational changes in terms of structure and managementprocesses. This paper aims to explore the change management process through BPR implementation in Radiant OptoelectronicsCompany. At the same time, focusing on six interventions, including Open systems planning, Trans-organizational development (TD),Business process reengineering (BPR), Business Restructuring, Work Redesign, and Socio-technical Systems Approach (STS). Eachintervention is accompanied by its definitions, advantages and disadvantages, and comparison and contrast with other interventions.These interventions differ from each other primarily in terms of IT innovation, communication environment, and application in productdesign and performance. This report recommends BPR as the best intervention for Radiant Company to accomplish its goals because itemphasizes cost reduction, product and service quality, and organizational system speed. Besides, there is evidence that companies thatimplement BPR enjoy significant benefits in improved customer satisfaction, productivity, and profitability. However, this study suggeststhat the company must be keen on this strategy since it is time-consuming and may harm people's jobs if proper plans are not done beforeimplementation. Other issues that the company might experience due to poor planning include lack of sustained managementcommitment and leadership, unrealistic scope and expectations, resistance to change, and higher demands
Bisphenol A Release from Orthodontic Clear Aligners: An In-Vitro Study
Authors:   Department of Orthodontics, College of Dentistry, University of Tennessee Health Science Center, Memphis 38163, Tennessee, United States, Katras Sydney , Ma Dejian ,   Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States, Dayeh Ayman al ,   Department Orthodontics, College of Dentistry, University of Tennessee Health Science Center, Memphis 38163, Tennessee, United States, Tipton David ,   Department of Bioscience Research, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States
Published: August 2021

Bisphenol A (BPA) is a widely used synthetic compound that has been identified as an endocrine disruptor. It has been linked to adverse health effects such as developmental defects, infertility in both men and women, cardiovascular disease, and obesity. There has been increased interest in BPA’s effects on the developing fetus and data has revealed that doses below the presumed safe dose can produce harmful effects. Orthodontic clear aligner therapy is a popular treatment modality that involves the patient wearing sets of plastic aligners up to 22 hours per day for the duration of treatment. The BPA release from these aligners was rarely investigated. The objective of this study was to detect, quantify, and compare the amount of BPA released by 3 popular brands of orthodontic aligners in artificial saliva, artificial gastric fluid, and ethanol. Equal amounts of SmileDirectClub®, Invisalign®, and Essix Ace® aligners were placed in sterile glass vials and submerged in 5.5mL artificial saliva, artificial gastric fluid, and ethanol. Samples were incubated at 37°C and 1 mL aliquots were removed at various time points. Samples were prepared and analyzed using high performance liquid chromatography tandem mass spectrometry. BPA was released from all three brands of aligners with great variability. Peak BPA concentrations were detected in artificial saliva; Smile Direct Club® produced 5.0 ng/mL after 20 days, Invisalign® released 3.5ng/mL after 24 hours, and Essix Ace® released 6.3ng/mL after 10 days of incubation in artificial saliva. There was no significant difference in BPA concentration between the 3 types of aligners in the 3 media. When comparing time points, there was a significant increase of BPA release in the first 24 hours after incubation compared to the baseline (p<0.001). There is potential BPA release from orthodontic aligners. There was no significant difference in the amount of BPA released between the three types of aligners at any time point. The majority of BPA release occurred during the first 24 hours.
Serious Games Are Not Serious Enough for Myoelectric Prosthetics
Authors: Garske Christian Alexander , Dyson Matthew , Dupan Sigrid , Morgan Graham , Nazarpour Kianoush
Published: August 2021

Serious games show a lot of potential for use in movement rehabilitation (eg, after a stroke, injury to the spinal cord, or limb loss). However, the nature of this research leads to diversity both in the background of the researchers and in the approaches of their investigation. Our close examination and categorization of virtual training software for upper limb prosthetic rehabilitation found that researchers typically followed one of two broad approaches: (1) focusing on the game design aspects to increase engagement and muscle training and (2) concentrating on an accurate representation of prosthetic training tasks, to induce task-specific skill transfer. Previous studies indicate muscle training alone does not lead to improved prosthetic control without a transfer-enabling task structure. However, the literature shows a recent surge in the number of game-based prosthetic training tools, which focus on engagement without heeding the importance of skill transfer. This influx appears to have been strongly influenced by the availability of both software and hardware, specifically the launch of a commercially available acquisition device and freely available high-profile game development engines. In this Viewpoint, we share our perspective on the current trends and progress of serious games for prosthetic training.
Hemodialysis Record Sharing: Solution for Work Burden Reduction and Disaster Preparedness (Preprint)
Authors: Ido Keisuke , Miyazaki Mariko , Nakayama Masaharu
Published: August 2021

BACKGROUND

After the Great East Japan Earthquake in 2011, backup systems for clinical information were launched in Japan. The system in Miyagi Prefecture called the Miyagi Medical and Welfare Information Network (MMWIN) is used as a health information exchange network to share clinical information among various medical facilities for patients who have opted in. Hospitals and clinics specializing in chronic renal failure require patients’ data and records during hemodialysis to facilitate communication in daily clinical activity and preparedness for disasters.

OBJECTIVE

This study aimed to facilitate the sharing of clinical data of patients undergoing hemodialysis among different hemodialysis facilities.

METHODS

We introduced a document-sharing system to make hemodialysis reports available on the MMWIN. We also recruited hospitals and clinics to share the hemodialysis reports of their patients and promoted the development of a network between emergency and dialysis clinics.

RESULTS

In addition to basic patient information as well as information on diagnosis, prescription, laboratory data, hospitalization, allergy, and image data from different facilities, specific information about hemodialysis is available, as well as a backup of indispensable information in preparation for disasters. As of June 1, 2021, 12 clinics and 10 hospitals of 68 dialysis facilities in Miyagi participated in the MMWIN. The number of patients who underwent hemodialysis in Miyagi increased by more than 40%.

CONCLUSIONS

Our backup system successfully developed a network of hemodialysis facilities. We have accumulated data that are beneficial to prevent the fragmentation of patient information and would be helpful in transferring patients efficiently during unpredictable disasters.
Use of an iPad App (Aid for Decision-making in Occupational Choice) for Collaborative Goal Setting in Interprofessional Rehabilitation: Qualitative Descriptive Study (Preprint)
Authors: Strubbia Carla , Levack William MM , Grainger Rebecca , Takahashi Kayoko , Tomori Kounosuke
Published: August 2021

BACKGROUND

Goal setting is a key part of the rehabilitation process. The use of technology and electronic tools such as smartphone apps and websites has been suggested as a way of improving the engagement of users in meaningful goal setting and facilitating shared decision-making between patients and health professionals.

OBJECTIVE

This study aims to describe experiences of health professionals and patients in the use of the English language version of the iPad app Aid for Decision-making in Occupational Choice (ADOC) to facilitate collaborative goal setting in rehabilitation.

METHODS

We recruited participants from 3 acute and postacute care rehabilitation wards in both public and private organizations in New Zealand. Participants were registered allied health professionals, including physiotherapists, occupational therapists, and speech-language therapists, who engage in goal setting as part of their normal work, and their adult patients. We collected data via semistructured interviews to gather information about the experiences of the participants in the use of ADOC for goal setting. Data were analyzed with thematic analysis.

RESULTS

A total of 8 health professionals and 8 patients participated in the study. Six main themes emerged from the data: changing patients’ perspective on what is possible, changing health professionals’ perspective on what is important, facilitating shared decision-making, lack of guides for users, logistic and organizational barriers, and app-related and technical issues.

CONCLUSIONS

Health professionals and patients found ADOC to be a valuable tool when setting shared rehabilitation goals. The use of ADOC promoted a patient-centered approach that empowered patients to engage in collaborative goal setting. The technological limitations of the app that negatively impacted experiences can be addressed in the future implementation of ADOC in rehabilitation settings.
Optimizing Coaching During Web-Based Relationship Education for Low-Income Couples: Protocol for Precision Medicine Research (Preprint)
Authors: Hatch S Gabe , Lobaina Diana , Doss Brian D
Published: August 2021

BACKGROUND

In-person relationship education classes funded by the federal government tend to experience relatively high attrition rates and have only a limited effect on relationships. In contrast, low-income couples tend to report meaningful gains from web-based relationship education when provided with individualized coach contact. However, little is known about the method and intensity of practitioner contact that a couple requires to complete the web-based program and receive the intended benefit.

OBJECTIVE

The aim of this study is to use within-group models to create an algorithm to assign future couples to different programs and levels of coach contact, identify the most powerful predictors of treatment adherence and gains in relationship satisfaction within 3 different levels of coaching, and examine the most powerful predictors of treatment adherence and gains in relationship satisfaction among the 3 levels of coach contact.

METHODS

To accomplish these goals, this project intends to use data from a web-based Sequential Multiple Assignment Randomized Trial of the OurRelationship and web-based Prevention and Relationship Enhancement programs, in which the method and type of coach contact were randomly varied across 1248 couples (2496 individuals), with the hope of advancing theory in this area and generating accurate predictions. This study was funded by the US Department of Health and Human Services, Administration for Children and Families (grant number 90PD0309).

RESULTS

Data collection from the Sequential Multiple Assignment Randomized Trial of the OurRelationship and web-based Prevention and Relationship Enhancement Program was completed in October of 2020.

CONCLUSIONS

Some of the direct benefits of this study include benefits to social services program administrators, tailoring of more effective relationship education, and effective delivery of evidence- and web-based relationship health interventions.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/33047
The Packing Chromatic Number of Different Jump Sizes of Circulant Graphs
Authors:   Department of Mathematics, Bangalore University, Jnanabharathi Campus Bangalore - 560 056 (India), CHALUVARAJU B. , KUMARA M. ,   Department of Mathematics, Bangalore University, Jnanabharathi Campus Bangalore - 560 056 (India)
Published: August 2021

The packing chromatic number χ_{p}(G) of a graph G = (V,E) is the smallest integer k such that the vertex set V(G) can be partitioned into disjoint classes V1 ,V2 ,...,Vk , where vertices in Vi have pairwise distance greater than i. In this paper, we compute the packing chromatic number of circulant graphs with different jump sizes._{}