bluuebunny/crossref_metadata_2025 huggingface dataset:
A Systematic Review with Meta-analysis of Studies Comparing Response to Experimentally-evoked Pain Between Obese and Non-Obese Individuals
Authors: Astita Rehab , Tashani Osama A. , Paley Carole A. , Sharp Duncan , Johnson Mark I.
Published: August 2018

Background:

The relationship between obesity and pain remains unclear. The aim of this systematic review was to determine whether response to experimentally-evoked pain differed between obese and non-obese individuals. Studies that compared responses to experimentally-evoked pain between obese and non-obese human participants post-puberty (i.e. >16 years) were sought. Eligible studies published between January 1950 and May 2017 were identified by searching OVID, MEDLINE, EMBASE and Science Direct.

Explanation:

Methodological quality of included studies was assessed using the ‘QualSyst’ questionnaire. Of 1106 references identified only nine studies (683 participants) were eligible for review. Pressure pain was assessed in five studies and electrical pain in three studies. Two studies investigated thermal pain. Obesity was categorized according to body mass index (BMI) or as weight as a percentage of ideal body weight. Six of the nine included studies were of low methodological quality. There was a lack of extractable data to pool for meta-analysis of studies using thermal or electrical pain. A forest plot of data extracted from four studies on pressure pain threshold found no differences between obese and non-obese groups (overall effect size was Z=0.57, p=0.57).

Conclusion:

Small sample size was the main limitation in all studies. Participants with obesity were more sensitive to mechanical noxious stimuli than non-obese participants in three of five studies. However, overall, it was not possible to determine whether there are differences in pain sensitivity response to experimental stimuli between obese and non-obese individuals.
A Bandwidth and Energy Aware QoS Routing Protocol for Enhanced Performance in Ad-hoc Networks
Authors: Bharadwaj Priyanka , Balhara Surjeet
Published: August 2018

Background & Objective:

There are some challenging issues such as providing Quality of
Service (QoS), restricted usage of channels and shared bandwidth pertaining to ad-hoc networks in a
dynamic topology. Hence, there is a requirement to support QoS for the application environment and
multimedia services in ad-hoc networks with the fast growing and emerging development of information
technology. Eventually, bandwidth is one of the key elements to be considered.

Methods:

Energy aware QoS routing protocol in an ad-hoc network is presented in this article.

Results and Conclusion:

The simulation results indicate that the improved protocol outperforms Adhoc
On-Demand Distance Vector (AODV) routing protocol in terms of QoS metric such as throughput,
packet delivery ratio, loss rate and average delay.
Motion Detection and Face Recognition for CCTV Surveillance System
Authors: Nurhopipah Ade , Harjoko Agus
Published: August 2018

Closed Circuit Television (CCTV) is currently used in daily life for a variety purpose. Development of the use of CCTV has transformed from a simple passive surveillance into an integrated intelligent control system. In this research, motion detection and facial recognation in CCTV video is done to be a base for decision making to produce automated, effective and efficient integrated system. This CCTV video processing provides three outputs, a motion detection information, a face detection information and a face identification information. Accumulative Differences Images (ADI) used  for motion detection, and Haar Classifiers Cascade used  for facial segmentation. Feature extraction is done with Speeded-Up Robust Features (SURF) and Principal Component Analysis (PCA). The features was trained by Counter-Propagation Network (CPN). Offline tests performed on 45 CCTV video. The test results obtained a motion detection success rate of 92,655%, a face detection success rate of 76%, and a face detection success rate of 60%. The results concluded that the process of faces identification through CCTV video with natural background have not been able to obtain optimal results. The motion detection process is ideal to be applied to real-time conditions. But in combination with face recognition process, there is a significant delay time.
DESIGN AND PERFORMANCE VERIFICATION OF NEWLY DEVELOPED DISPOSABLE STATIC DIFFUSION CELL FOR DRUG DIFFUSION/PERMEABILITY STUDIES
Authors: Yadav Ankit Kumar , Garg Varun , Gulati Monica , Bansal Parikshit , Bansal Kompal , Kaur Puneet , Singh Sachin Kumar , Mittal Amit , Narang Rakesh , Kumar Bimlesh , Pandey Narendra Kumar , Mittal Amit , Wadhwa Sheetu , Khatik Gopal Lal , Banerjee Mayukh , Mohanta Souvik , Sinha Shubham , Jyoti Jivan , Som Sananda , Kapoor Bhupinder , Singh Saurabh
Published: August 2018

Objectives: The present study describes a disposable static diffusion cell for in vitro diffusion studies to achieve better results as compared to well existing Franz diffusion cell (FDC) in terms of the absence of bubbles, variable receptor compartment, ease of handling, and faster results.Materials and Methods: The cell consists of a cup-shaped donor compartment made of semi permeable that could be either cellophane membrane or, animal skin fitted to a rigid frame, which is supported on a plastic plate that contains a hole for the sample withdrawal. The receptor compartment is a separate unit, and it could be any container up to 500ml volume capacity. The most preferred receptor compartment is glass beaker. In the present study, goatskin was used as semi-permeable membrane and verification of its performance was carried out through diffusion studies using gel formulations of one each of the four-selected biopharmaceutical classification system (BCS) class drugs. Metronidazole, diclofenac sodium, fluconazole, and sulfadiazine were used as model drugs for BCS Class I, II, III, and IV, respectively.Results: The newly developed diffusion cell (NDDC) was found to provide faster and more reproducible results as compared to FDC. At the time interval of 24 h, the cell was found to exhibit a higher diffusion of metronidazole, diclofenac sodium, fluconazole, and sulfadiazine by 0.65, 0.65, 0.32, and 0.81 folds, respectively. The faster release obtained with NDDC was attributed to a larger surface area of skin as compared to that in FDC.Conclusion: It was concluded that better reproducibility of results could be achieved with NDDC.
INFLUENCE OF FORMULATION PARAMETERS ON DISSOLUTION RATE ENHANCEMENT OF ACYCLOVIR USING LIQUISOLID FORMULATION
Authors: Hazemba Kubota Mwaka , Jyoti Jivan , Wadhwa Sheetu , Som Sananda , Mohanta Souvik , Yadav Ankit Kumar , Kumar Bimlesh , Garg Varun , Sharma Deep Shikha , Khursheed, Rubiya , Gulati Monica , Singh Sachin Kumar
Published: August 2018

Objective: The objective of this research work is to explore the use of liquisolid technique in enhancement of acyclovir dissolution rate. This current study was planned to assess the impact of different formulation variables, such as non-volatile liquid type and concentrations of acyclovir on its dissolution rates profile. Method: Acyclovir liquisolid tablets were prepared with Tween 60 (liquid vehicle), Microcrystalline cellulose PH 102 (acted as a carrier to turn liquid medication into free-flowing powder) and Syloid XDP (coating material). In vitro, drug dissolution rate of liquisolid formulations of acyclovir was performed and compared with pure acyclovir drug using USP dissolution apparatus (Type II) for 60 min at a paddle speed of 50 rpm and filled with 900 mL of distilled water. Results: The dissolution study showed that 94.1% of the drug was released in 60 min of ratio 10 while only 66% of the pure drug acyclovir was released in 60 min. Hence, present work concluded that the acyclovir dissolution rate profile has been improved with the formation of liquisolid formulations. Conclusion: From the present study, it may be ratified that the drug dissolution rate of acyclovir has been improved with the utilization of liquisolid formulations approach.
FORMULATION, SYSTEMATIC OPTIMIZATION, IN VITRO, EX VIVO, AND STABILITY ASSESSMENT OF TRANSETHOSOME BASED GEL OF CURCUMIN
Authors: Kaur Prabhjot , Garg, Varun , Bawa Palak , Sharma Roopesh , Singh Sachin Kumar , Kumar Bimlesh , Gulati Monica , Pandey Narendra Kumar , Narang Rakesh , Wadhwa Sheetu , Mohanta Souvik , Jyoti Jivan , Som Sananda
Published: August 2018

Objectives: The current work presents a formulation of curcumin-loaded transethosome (CRM-TE) in the form of a gel and its characterization.Methods: Thirteen formulations were prepared by varying the concentration of Phospholipon 90G as lipid, ethanol, and ratio of lipid: Span using Box- Behnken Design. The optimized formulation was characterized by vesicle size, entrapment efficiency, drug retention, drug permeation through skin, and morphology. Parameters of CRM-TE were compared to other vesicular systems that include liposomes, ethosomes, and transfersomes. Optimized CRM-TE was incorporated into gels, and comparative evaluation was performed. CRM-TE gel was kept at 5±3°C, 25±3°C, and 40±3°C for 180 days, further evaluated for entrapment efficacy and vesicle size.Results: CRM-TE showed 286.4 nm vesicle size, 61.2% entrapment efficiency, 19.8% drug retention, and 71.3% drug permeation at 24 h in the skin. It was found superior in terms of all the parameters as compared to other vesicular formulations. CRM-TE gel also exhibited best characteristics in terms of entrapment efficiency, drug retention, and drug permeation. CRM-TE gel exhibited better stability at 5±3°C in terms of vesicle size and entrapment efficiency as compared to other storage conditions.Conclusion: CRM-TE gel could offer efficient delivery of curcumin through topical route.
INVESTIGATION AND OPTIMIZATION OF FORMULATION PARAMETERS FOR SELFNANOEMULSIFYING DELIVERY SYSTEM OF TWO LIPOPHILIC AND GASTROINTESTINAL LABILE DRUGS USING BOX-BEHNKEN DESIGN
Authors: Kumar Bimlesh , Garg Varun , Singh Amarjeet , Pandey Narendra Kumar , Singh Saurabh , Panchal Sakshi , Melkani Indu , Raji Raji , Axel Manzi , Mohanta Souvik , Jyoti Jivan , Som Sananda , Gulati Monica , Bhatia Amit , T Prakash , Singh Sachin Kumar
Published: August 2018

Objective: Present research work aims toward codelivery of two hydrophobic drugs, curcumin (CRM) and duloxetine hydrochloride (DXH) through self-nanoemulsifying drug delivery systems (SNEDDS).Methods: Initially, binary mixture in the ratio of 1:1 was prepared and then loaded into SNEDDS. Box-Behnken design (BBD) was adopted to develop SNEDDS. As per the optimal design, 13 SNEDDS prototypes were prepared. Castor oil, tween-80 and Transcutol P® were used as oil, surfactant, and cosurfactant, respectively. To 1 mL of SNEDDS, 30 mg each of CRM and DXH was loaded (CRM-DXH- SNEDDS).Results: The design revealed that for mean droplet size, polydispersity index (PDI), as well as percentage drug loading, all the three factors, i.e. ratio of oil (a), surfactant (b), and cosurfactant (c) were found to give significant effect. Factor B showed the most significant effect on mean droplet size (y1). In case of PDI (y2), factors B and C exerted maximum influence, whereas, Factor A has shown non-significant effect. For percentage drug loading of drugs (y3 and y4), all the three factors were found to have the most significant effect. The optimized batch of CRM-DXH- SNEDDS having composition castor oil, tween-80, and Transcutol P® in the ratio: 2.17:5.22:2.61, revealed that the mean drug loading (%) of CRM and DXH in an optimized batch of SNEDDS was found to be 87.22±1.87 and 92.32±0.19%, respectively. The mean droplet size, PDI, and zeta potential of formed SNEDDS were observed as 113.14±1.14 nm, 0.20±0.026, and −13.2 mV, respectively.Conclusion: BBD provided optimal formula composition for SNEDDS for obtaining desirable drug loading, emulsion droplet size, and zeta potential.
STRUCTURAL CHARACTERISATION OF 5-HYDROXYTRYPTAMINE2A RECEPTOR IN HOMO SAPIENS BY IN - SILICO METHOD
Authors: Singh Soni , Jha Alok
Published: August 2018

Objective: Structural characterization of 5-hydroxytryptamine (5-HT)2A receptor in homo sapiens using in silico method.Methods: In silico approach has particularly providing a realistic representation needed to understand the fundamental molecular structure of a serotonin receptor. The structure has been generated using Swiss model, Modeller 9.14, Phyre2, and Geno three-dimensional, which was visualized using PyMol, and validated by Procheck and ERRAT analysis along with the values of different secondary structures mapping to diverse sections of the Ramachandran plot.Results: We compared all different models. Further structural analysis suggested that the structure of 5-HT2A is a monomer with 18 alpha helices, seven beta sheets, and one disulfide bridge. There is no signal peptide region in the protein sequence. The structure contains mostly polar and aromatic amino acid as suggested by using hydropathy plot. However, in both partitioning systems bilayer to water and water to bilayer, there are some hydropathy predicted segments, which are also transmembrane segments. Finally, the pore features, including diameter profile, size, and shape, were determined by porewalker, and the shape of the pore was found to be UDSD.Conclusion: This study suggested that 5-HT2A receptor interaction with its natural ligand serotonin and other inhibitor compounds would further additional information about G protein-coupled receptors. The 5-HT2A receptor could be an important target for therapeutics development.
PREVALENCE AND DRUG RESISTANCE IN ACINETOBACTER SP. ISOLATED FROM INTENSIVE CARE UNITS PATIENTS IN PUNJAB, INDIA
Authors: Kaur Tanvir , Putatunda Chayanika , Oberoi Aroma , Vyas Ashish , Kumar Gaurav
Published: August 2018

Objective: This study was designed to study the prevalence and antibiotic susceptibility patterns of Acinetobacter sp. as isolated from patients lodged in intensive care units (ICUs) of a tertiary care hospital, Ludhiana, Punjab, India.Methods: The clinical samples were simultaneously streaked on Blood agar and MacConkey agar. The identification of the bacterial isolates was carried out with the aid of Gram stain, motility test and along with a combination of other commonly employed biochemical tests. The antimicrobial susceptibility testing (AST) of all the bacterial isolates was carried out on Muller-Hinton agar through Kirby-Bauer disc diffusion method.Results: Acinetobacter sp. formed a fair allowance contributing at 42% among all ICU culture positive samples. The respiratory tract samples had a major share at 63.15% for all samples attributed to be positive for Acinetobacter sp. nosocomial etiology. The antibiotic sensitivity pattern portrayed that more than 95% of Acinetobacter sp. isolates were multiple drug resistant (MDR) whereas >50% Acinetobacter sp. showed extensive drug resistant (XDR). The last resort for such Acinetobacter sp. nosocomial infections is left to colistin and polymyxin B.Conclusion: Acinetobacter sp. is a highly prevalent microorganism among ICU patients of Ludhiana, Punjab, India, while its potential to acquire resistance toward commonly used antibiotics represents it as a grave threat to the health-care industry, therefore signifying the need for its regular monitoring in the health-care setups.
COMPARATIVE ASSESSMENT OF IN VITRO ANTIMICROBIAL ACTIVITY OF CURCUMA CAESIA ROXB. AND CURCUMA AMADA ROXB
Authors: Kaur Randeep , Kaur Barinderjit , Suttee Ashish , Kalsi Vandna
Published: August 2018

Objective: The aim of the present study was to compare the in vitro antimicrobial activity of Curcuma caesia Roxb. and Curcuma amada Roxb. family Zingiberaceae. Both plants have been used traditionally for curing a number of diseases and ailments. The plants have been specifically used in skin problems and inflammatory conditions.Methods: Each plant material was extracted with dichloromethane (DCM) and ethanol. All extracts were subjected to preliminary phytochemical screening. The antibacterial activity of the extracts was tested against two Gram-positive (Staphylococcus aureus, Streptococcus pyogenes), and two Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) using the cup-plate method. The standard drug used was ofloxacin (0.2 ml) at a concentration of 5 mg/ml. The antifungal activity was tested against Aspergillus fumigatus, and Candida albicans using the cup-plate method and clotrimazole (10 mg/ml) was taken as standard reference.Results: Phytochemical screening performed on the extracts has shown the presence of various constituents such as glycosides, carbohydrates, saponins, phytosterols, resins, flavonoids, and diterpenoids. On comparing both species, C. amada was found to be stronger growth inhibitor against both Gram-positive and Gram-negative strains. C. caesia ethanol extract at a dose of 200 mg/ml was most effective and C. amada DCM extract 100 mg/ml was least effective in case of antifungal activity against C. albicans. In case of A. fumigatus, C. caesia DCM extract 100 mg/ml was least effective and C. caesia ethanol extract 200 mg/ml was most effective.Conclusion: The present study provides the information on phytochemical screening and antimicrobial activities of extracts prepared from two plants of family Zingiberaceae, i.e., C. caesia Roxb. and C. amada Roxb.
NANOSTRUCTURED LIPID CARRIERS (NLCS): A PROMINENT TOPICAL DELIVERY SYSTEM FOR COENZYME Q10 AND MYRICA ESCULENTA LEAVES EXTRACT FOR ANTI-AGING POTENTIAL
Authors: Kumar Prashant , Singh Anita
Published: August 2018

Objective: In this study, Myrica esculenta (ME) leaves extract along with Coenzyme Q10 was entrapped in nanostructured lipid carriers (NLCs). The formulation variables were successfully optimized using 23 factorial design.Methods: Preparation of NLC was carried out by solvent injection technique. The formulation of NLC was consisting of the methanolic extract of Myrica esculenta leaves and Coenzyme Q10 as key ingredients. Oleic Acid (OA) was taken as liquid lipid, Precirol ATO 5 (PATO) as solid lipid, and Poloxamer 407 (P407). The formulation variables were statically optimized using 23 factorial design, followed by the characterization of the formulation.Results: The results demonstrated that the best optimized NLC formulation F5 of Coenzyme Q10 and plant extract exhibited the smallest size 169.46 nm and highest entrapment efficiency 90.06±0.171 %. Furthermore, it showed good physical stability at 28 d after preparation.Conclusion: The developed NLCs of Q10-ME extract from this study could be explored as the effective anti-ageing formulation.
Black Cohosh (Actaea Racemosa) for the Mitigation of Menopausal Symptoms: Recent Developments in Clinical Safety and Efficacy
Authors: Mahady Gail B , Doyle Brian , Locklear Tracie , Cotler Scott J , Guzman-Hartman Grace , Krishnaraj Rajabather
Published: August 2018

The purpose of this article is to assess recent data supporting the safety and efficacy of black cohosh products for the mitigation of menopause-related symptoms. Searches of the published literature in Napralert, Cochrane Library and PubMed databases were performed from 2003 to 2006. Information from drug regulatory agencies from five different countries was obtained to evaluate safety. While there are a few contradictory studies, the majority of the clinical trials indicate that extracts of black cohosh ( Actaea racemosa L.) improve menopause-related symptoms. However, to date, at least 50 cases of possible hepatotoxicity have been reported. Although previous safety reviews suggest that black cohosh is well tolerated, the increasing numbers of these case reports indicates that further preclinical toxicological evaluations of black cohosh are urgently needed. At this time, it appears prudent to advise menopausal women with underlying liver disease, autoimmune diseases or those taking medications that may impact liver function not to use products containing black cohosh.
How Old is Too Old for Fertility Treatment?
Authors: Howland Elizabeth J , Kennedy C R
Published: August 2018

Women are delaying starting their families. High-profile women such as Cherie Blair and Madonna are having successful pregnancies with healthy babies in their forties. Is this sending out messages to women that delaying conception during their twenties and thirties is a good idea? Fertility treatment can overcome certain age-related hurdles but is certainly not the magic wand some expect it to be.
Management of Polycystic Ovary Syndrome
Authors: Yasmin Ephia , Balen Adam H
Published: August 2018

Polycystic ovary syndrome is a common endocrinological problem in women of reproductive age. Polycystic ovary syndrome is a heterogenous disorder and patients may attend different clinics depending on the main complaint. The exact pathophysiology of polycystic ovary syndrome remains obscure, although there have been insights that have thrown light on this condition. Consensus on the definition of the syndrome has only been recently achieved. The management of polycystic ovary syndrome poses a challenge to the physician as responses to the different treatment regimes have proved to be inconsistent. Diet and lifestyle advice, restoration of menstrual cycle regularity, treatment of hyperandrogenism, treatment of infertility and prevention of long-term consequences form the basis of polycystic ovary syndrome management. This review aims to provide the reader with the latest evidence in the treatment of polycystic ovary syndrome, as well as focus on some of the controversies surrounding its management.
Random Start or Emergency IVF/in vitro Maturation: A New Rapid Approach to Fertility Preservation
Authors: Robertson David Mark , Gilchrist Robert B , Ledger William Leigh , Baerwald Angela
Published: August 2018

There is a need to develop rapid protocols for ovarian stimulation for women who wish to preserve their fertility following diagnosis of cancer. Conventional gonadotropin stimulation protocols are lengthy and are delayed until the start of the next menstrual period, potentially compromising cancer treatments. The development of random start IVF/ in vitro maturation has made significant strides for enabling couples undergoing cancer therapy to achieve a family. However, several unanswered questions still remain. What do we know about the endocrinology of stimulating ovarian follicular activity outside the established protocols of stimulation during the follicular phase? This article explores what is known about antral follicle development during the menstrual cycle, novel ovarian stimulation proposals for optimizing assisted reproductive therapies in women, and direction.
Bremelanotide for Female Sexual Dysfunctions in Premenopausal Women: A Randomized, Placebo-Controlled Dose-Finding Trial
Authors: Clayton Anita H , Althof Stanley E , Kingsberg Sheryl , DeRogatis Leonard R , Kroll Robin , Goldstein Irwin , Kaminetsky Jed , Spana Carl , Lucas Johna , Jordan Robert , Portman David J
Published: August 2018

Aim: Evaluate efficacy/safety of bremelanotide (BMT), a melanocortin-receptor-4 agonist, to treat female sexual dysfunctions in premenopausal women. Methods: Patients randomized to receive placebo or BMT 0.75, 1.25 or 1.75 mg self-administered subcutaneously, as desired, over 12 weeks. Primary end point was change in satisfying sexual events/month. Secondary end points included total score changes on female sexual function index and female sexual distress scale-desire/arousal/orgasm. Results: Efficacy data, n = 327. For 1.25/1.75-mg pooled versus placebo, mean changes from baseline to study end were +0.7 versus +0.2 satisfying sexual events/month (p = 0.0180), +3.6 versus +1.9 female sexual function index total score (p = 0.0017), −11.1 versus −6.8 female sexual distress scale-desire/arousal/orgasm total score (p = 0.0014). Adverse events: nausea, flushing, headache. Conclusion: In premenopausal women with female sexual dysfunctions, self-administered, as desired, subcutaneous BMT was safe, effective, and well tolerated (NCT01382719).
Spontaneous Bilateral Torsion of Fallopian Tubes Presenting as Primary Infertility
Authors: Murphy Erin M , Pereira Nigel , Melnick Alexis P , Spandorfer Steven D
Published: August 2018

Background: Spontaneous torsion of the fallopian tubes is a rare condition, usually seen in acute settings or as incidental findings during laparoscopy. Presentation of the case: A 34-year-old nulligravid woman with inability to conceive for 7 months presented to our center. Her hysterosalpingography revealed a blind-ending right fallopian tube, and a blocked and dilated left fallopian tube. Laparoscopy showed a long, auto-amputated right fallopian tube, disconnected from the fimbriae and a long, dilated left fallopian tube, with several twists around its axis. Bilateral salpingectomy was performed. The patient subsequently underwent IVF, resulting in an ongoing pregnancy. Conclusion: Spontaneous torsion of the fallopian tubes can manifest as primary infertility without any antecedent symptoms and should be considered in the differential diagnosis of bilateral tubal obstruction.
Targeted Therapy in Ovarian Cancer
Authors: Lim Hui Jun , Ledger William
Published: August 2018

Among female-specific cancers worldwide, ovarian cancer is the leading cause of death from gynecologic malignancy in the western world. Despite radical surgery and initial high response rates to first-line chemotherapy, up to 70% of patients experience relapses with a median progression-free survival of 12–18 months. There remains an urgent need for novel targeted therapies to improve clinical outcomes in ovarian cancer. This review aims to assess current understanding of targeted therapy in ovarian cancer and evaluate the evidence for targeting growth-dependent mechanisms involved in its pathogenesis. Of the many targeted therapies currently under evaluation, the most promising strategies developed thus far are antiangiogenic agents and PARP inhibitors.
Promised future and possible future: science communication and technology at World's Fairs and theme parks
Authors: Herrera-Lima Susana , Martin Daniela
Published: August 2018

World’s Fairs and scientific-technological theme parks have been
propitious places for the communication of science and technology through
modernity. This work addresses the issue of the construction of public
discourse about the future within these sites, as well as the changing role
attributed to science and technology as mediators in the relationships
between nature and society. In both fairs and parks, science and
technology play a leading role in the construction of the discourse about
the desirable and achievable future. The practices of science
communication and technology have specific forms, strategies and
objectives, depending on the purposes of the discourse enunciators at
different historical moments. This is exemplified through two cases: the
1939 New York World’s Fair and the EPCOT center in the U.S.
Agroecological estimation of the mineralogical composition of the soil
Authors: Savich V I , Belopukhov S L , Kotenko M E , Gukalov V V , Ilicheva P I , Fedorova T A
Published: August 2018

It is shown that the mineralogical composition of the soil is a factor when considering the lithology of soil at a lower hierarchical level. The mineralogical composition and determines the content ratio in the soil of nutrients and toxicants, ion exchange processes, soil resistance to degradation of soil fertility. It is the matrix of the formation of soil and regulates the transformation, migration and accumulation in soil of substances, energy and information of environmental and human impact.
Leaf pigment content and accumulation of dry matter by potato plant as affected by sulfate fertilizer in green house experiment
Authors: Nagornyy V D , Nourouson Arimalala R -
Published: August 2018

From the time mineral fertilizers were used single superphosphate have been the main source of phosphate in plant nutrition. This fertilizer contains nor only 19-21% of P2O5 but also sulfate in form of gypsum and small amount of sulfuric acid. As a result, application of one kg of superphosphate enriched the soil with 80-100 g of sulfates. During last 40-50 years single superphosphate was replaced by concentrated mineral fertilizers which contain up to 42-52% of P2O5. And now on some soils the main source of sulfurbecome precipitations which bring sulfur oxides produced by chemical enterprises and exhaust fumes of machinery. As a consequence of this there are not rear cases when growing plants, and more often legumes, oil and root corps, show signs of sulfur deficit. Optimal levels of sulfur content in plant leaves well established. But there is obvious interest to get more objective data on physiological processes which are more sensitive to deficit of this plant nutrient and on preferable time of sulfur application. Influence of sulfate and other anions of potassium fertilizers on leaf pigment content and accumulation of dry matter by potato plants are presented and discussed in the article.
Georreferenciación del mapa histórico de Couto Reis de Campos en 1785, Rio de Janeiro, a finales del siglo XVIII
Authors: Porto da Gama Mylena , Valencia Villa Carlos Eduardo
Published: August 2018

La georreferencia de mapas históricos coloniales de las Américas que representan extensas áreas rurales ha sido un desafío metodológico para la historiografía que utiliza los sistemas de información geográfica. Este artículo presenta la georreferenciación del mapa de Couto Reis de 1785 para la región de Campos en Río de Janeiro. Así, explica cuál es el problema de georreferenciar este tipo de mapas y expone en detalle el método usado para hacerlo. Además, muestra algunos de los posibles aportes que tiene para la historiografía el trabajo con este tipo de fuentes. En ese sentido, este texto tiene el doble objetivo, primero, de explicar el método, y segundo, de invitar al uso de los sistemas de información geográfica en la historia.
Efficacy of Skill DevelopmentTechniques: Empirical Evidence
Authors: Gul Eijaz
Published: August 2018

Making students skillful is the ultimate aim of teaching. The teacher who feel that their jobs are over once they explain and demonstrates the lesson in the class is certainly on the defective side of thinking. Rather,students must be guided towardsthe objectives of learning demonstrated through modeling, and given ample practice to handle learning independently. This paper elucidates various techniques available forskill development by studying the case of 75 students. Their views regarding learning were gathered through a questionnaire. A statistical analysis of their views was carried out, after which they were given a skill to practice through a selected technique which they considered asthe most effective technique for skill development. It was empirically concluded thatstudentslearned the skill more rapidly when they are allowed to use their initiative and judgment in a mutual practice technique of skill development. At the end, guidelines for effective skill development have been suggested which could be adopted by teacher for skill training of students
Faktor-Faktor yang Mempengaruhi Konsumen Dalam Pemilihan Kuliner di Kawasan Wisata Alam Kemuning
Authors: Mangifera Liana , Isa Muzakar , Wajdi M.Farid
Published: August 2018

Penelitian ini bertujuan menganalisis pengaruh harga, citra perusahaan, kualitas produk dan lokasi terhadap keputusan konsumen dalam pemilihan kuliner di kawasan wisata alam kemuning Karanganyar. Populasi penelitian ini adalah konsumen yang pernah melakukan wisata ke kawasan kemuning dan juga pernah melakukan pembelian makanan. Pemilihan sampel menggunakan metode purposive sampling. Jumlah sampel yang diambil dalam penelitian ini sebanyak 94 orang responden. Penelitian ini menggunakan data primer yang diambil menggunakan wawancara terstruktur dengan bantuan kuesioner. Analisis data yang digunakan adalah analisis regresi berganda. Simpulan yang dihasilkan adalah adalah harga dan lokasi berpengaruh positif dan signifikan terhadap keputusan pembelian, sedangkan citra merek dan kualitas produk berpengaruh positif tetapi tidak signifikan terhadap keputusan pembelian pemilihan kuliner di kawasan kemuning karanganyar. Lokasi paling berpengaruh dalam pemilihan tempat kuliner di kawasan wisata alam kemuning.
Application of Technology in the Digital Era Education
Authors: Hashim Harwati
Published: August 2018

The fact that technology plays a much larger role in the digital era than it did for previous generations has made today’s generation having a high level of technological literacy. The increase in this literacy coupled with recent technological advances has led to the expansion of technology in education. From the millennial to Gen-Z, these are the generations that are coming into the classroom today and they share unique characteristics that define their generations.  These generations expect to be engaged in their learning and they do not do well being passive learners.  Hence, technology has to be embraced in today’s education and teachers have to apply technology as part of the students learning.  This paper reviews the generations of learners that teachers are having today and how these generations impacted the transformation of education in the digital era.  This paper also presents some of the emerging technologies and discusses the needs of pedagogical transformation to invent new forms of teaching and learning as well as the importance of redesigning and rethinking education in the digital era.
MERANCANG KEGIATAN PEMBELAJARAN SEJARAH MELALUI KOMIK: RESPON TERHADAP TANTANGAN KURIKULUM 2013
Authors: Anwar Aisiah
Published: August 2018

Crucial issues, as well as the classic issues that have always been the subject of historical learning problems related to activities or learning processes that tend to be monotonous, boring and lack of innovation and creativity of the teachers in designing historical learning activities that can generate students interest and motivation in learning the history. The 2013 curriculum presents a special challenge for teachers to design studentcentered learning activities using a scientific approach through problembased learning models, project-based learning and discovery learning models. One solution that can be done by history teachers in answering the challenges of the 2013 curriculum is to design learning activities through historical comics. Historical teachers can apply problem-based learning models by utilizing historical comics that are already available on the market as well as on the internet. In addition, history teachers can also apply project-based learning models through activities of making comic history by learners in accordance with the historical learning material learned. The design of learning activities through comics is expected to create innovations in the form of historical comics as a result of the design and creativity of the students. The process of learning history through the making of comics is certainly based on a scientific approach and student-centered. History teachers are asked to direct, provide solutions and suggestions to improve the quality of learning activities and learning outcomes as well as the quality of historical comic produced by students.
As proposições de uma escola inclusiva na concepção de professores de educação especial: algumas problematizações
Authors: Thesing Mariana , Costas Fabiane
Published: August 2018

Que ações são necessárias para a efetivação de uma escola, de fato, inclusiva, nos moldes propostos pela Política Nacional de Educação Especial na Perspectiva da Educação Inclusiva (Brasil. MEC 2008)? Com base nesse questionamento, este artigo apresenta resultados de uma pesquisa realizada com professores de educação especial atuantes em quatro municípios do Rio Grande do Sul que indicam ações necessárias para a criação de uma nova escola: uma escola inclusiva. A pesquisa, baseada em uma abordagem qualiquantitativa (Marconi; Lakatos, 2009), com a utilização de um questionário disponível no Formulários Google, teve como objetivo conhecer as trajetórias formativas e as características dos contextos de atuação docente desses professores. Com base em referências como Garcia (2013, 2014), Kassar (2014), Michels (2011) e Correia (2010), este texto apresenta parte dos dados coletados na pesquisa e problematiza as proposições dos professores de educação especial para a possibilidade de transformar as escolas em espaços efetivamente inclusivos. Como resultado deste estudo, percebe-se que a maioria dos professores participantes acreditam nos processos de inclusão nas escolas em que estão inseridos; contudo, sinalizam a importância de ações, de diferentes sujeitos envolvidos na educação escolar, para que a proposição de uma escola inclusiva se torne uma realidade.
Abordagem das desigualdades de gênero e diversidade sexual em sindicatos de trabalhadoras/es em educação: o caso da Confederação Nacional dos Trabalhadores em Educação (CNTE)
Authors: Vieira Ferreira Márcia Ondina , Orsato Andréia , Pereira dos Santos Luciano , Völz Klumb Coronel Márcia Cristiane
Published: August 2018

Estudos sobre gênero e diversidade sexual em organizações sindicais do campo educacional ainda são incipientes, e os que existem se voltam especialmente à participação sindical das mulheres, sem discutir as concepções das organizações sindicais. Algumas análises atribuem motivos para tais lacunas: sendo os sindicatos instituições “públicas”, existem para a atuação masculina; ou estão centrados em lutas consideradas de caráter universal, portanto, as ações ligadas a políticas de gênero seriam secundárias e até mesmo prejudiciais. Contudo, nas últimas duas décadas, as discussões têm avançado, sendo possível encontrar políticas sindicais mais atentas às questões de gênero e sexualidade, paulatinamente incorporando que diferenças em relação a gênero e orientação sexual são componentes de processos de distribuição de poder e desigualdade social. Buscando colaborar com a compreensão desse tema, o artigo tem por objetivo examinar atribuições e competências das secretarias voltadas a gênero e diversidade sexual em 25 sindicatos filiados à Confederação Nacional dos Trabalhadores em Educação (CNTE/Brasil), identificando se suas/seus dirigentes são do sexo feminino ou do sexo masculino. Os dados foram coletados por consulta aos estatutos das organizações e nominatas de suas diretorias, obtidos nas páginas web, por e-mail ou contato telefônico. Em suma, foi verificada a presença absolutamente majoritária de mulheres nas coordenações das secretarias, que têm atribuições, competências e nomenclaturas muito variadas, bem como um número muito pequeno de menções a questões relativas à diversidade sexual. Isso parece indicar, por um lado, uma representação ainda existente sobre supostas competências de homens e de mulheres, delegando a essas últimas cargos considerados de menor prestígio político. Por outro lado, denota um estágio ainda inicial dos debates a respeito, pois parece haver uma aceitação maior da institucionalização das questões relativas a gênero/mulher quando comparada com o debate sobre diversidade sexual, indicando nova clivagem e invisibilidade e/ou desconsideração das diferenças em termos de orientação sexual e identidade de gênero.
A sala de aula como um ambiente equipado tecnologicamente: reflexões sobre formação docente, ensino e aprendizagem nas séries iniciais da educação básica
Authors: Santos Verônica Gomes dos , Almeida Sandra Estefânia de , Zanotello Marcelo
Published: August 2018

Resultados positivos reportados na literatura (Zandvliet, 2012) sobre o uso da tecnologia de forma permanente e imersiva em sala de aula, ao livre dispor de professores e alunos, motivam a realização deste estudo qualitativo. Com o objetivo de identificar as contribuições de um ambiente tecnologicamente estruturado no processo de alfabetização de uma turma do 1º ano do ensino fundamental I de uma escola municipal da rede pública paulista, analisam-se as produções decorrentes de uma atividade relacionada à fabricação de massinha caseira pelas crianças. O envolvimento dos alunos na elaboração de textos, a utilização dos recursos tecnológicos, a motivação, a autonomia e a colaboração são evidências que mostram que tal estrutura pode ser um diferencial no cotidiano da sala de aula. São analisados também aspectos da constituição de saberes docentes para o uso didático da tecnologia com base no modelo TPCK (Mishra; Koehler, 2006), mediante relatos de quatro professores da escola. Há indícios de mudanças significativas no processo formativo rumo ao desenvolvimento da autonomia docente.
Em busca de uma iniciativa histórica africana: possibilidades e limites das práticas pedagógicas na educação básica
Authors: Araujo Débora Cristina de
Published: August 2018

Este artigo apresenta um conjunto de atividades desenvolvidas em turmas de 6º ano do ensino fundamental durante as aulas de língua portuguesa, com a proposta de promover rupturas epistemológicas na compreensão das crianças sobre cultura, estética e história africanas. Para tanto, utiliza como referenciais analíticos as produções das crianças, além de uma revisão teórica do campo das práticas pedagógicas e dos marcos legais que fundamentam a educação das relações étnico-raciais no Brasil. As modificações curriculares (ainda em curso) demandadas pela aprovação de um conjunto de leis, resoluções e diretrizes que fomentam o ensino de história e cultura afro-brasileira e africana na educação brasileira têm sido produzidas em campos de tensões, negociações e muitas vezes rupturas epistêmicas. Soma-se a forte tendência de conteúdos e práticas pedagógicas eurocêntricos, influenciados por um padrão de poder que emergiu como resultado do colonialismo moderno, a colonialidade. O que as práticas aqui descritas revelaram é que os limites ainda são muitos diante da força da colonialidade. O desafio que se apresenta à escola é, portanto, pensar outras possibilidades pedagógicas para subverter tal colonialidade e avançar na construção de um ensino fundamentado no reconhecimento de que a produção intelectual, política, cultural e social africana e afro-brasileira é necessária à formação escolar da população brasileira.
Alienation of Agricultural Fertilizer and Pesticide Suppliers: A Case Study in Adana
Authors: ÖZTORNACI Burak , AYAZ Dicle
Published: August 2018

'Green Revolution', a production form based on heavy use of chemicals, hybrid seeds, agricultural machinery and intensive irrigation has become widespread almost all around the world. It is claimed to have increased food production and solved the problem of starvation, but today is under debate because of its harmfull effects on environment and human health. The related literature has focused specifically on manufacturers and users of agricultural chemicals. However, there is an intermediate retailer ring, mostly agricultural engineers, where agricultural producers obtain their inputs and get information and advice on agricultural production. For this reason, in terms of public health and food safety, it is important to determine the retailers' level of sensitivity to environment and human health. The present study focused on the agricultural input retailers in the city of Adana, which is one of the most important basins in Turkey. Totally, 513 agricultural input retailers are located in Adana. In study, approximately 10% of these agricultural input retailers (50 retailers) were interviewed using face to face questionnaires. The study investigated their sensitivity to the environment and human health and also focused on the concept of alienation. Data obtained were evaluated using SPSS software and employing Chisquare independence tests. The study shows that, regardless of the level of education and income, the agricultural input retailers acknowledge that the products they market are harmful to the environment and human health but prefer to ignore this issue on account of financial and technical concerns.
Kamu Tarım Yatırımlarının Dağılımının Gini Katsayısı ile Ölçülmesi: Kuzeydoğu Anadolu Bölgesi Üzerine Bir İnceleme (1999-2017)
Authors: YAZGAN Şekip , KADANALI Esra
Published: August 2018

Çalışmada Kuzeydoğu Anadolu (TRA) Bölgesi illeri ve alt bölgelerinde kamu tarım yatırımlarının 1999-2017 yılları arasında hangi ölçüde eşitsiz dağıldığı Gini indeksi yardımıyla hesaplanmaktadır. Ampirik bulgular TRA Bölgesi ve alt bölgeleri TRA1 ve TRA2 Bölgelerine ait kamu tarım yatırımları Gini Katsayısı değerlerinin söz konusu dönemin başlarında nispeten düşük seviyelerde olduğunu yani kamu tarım yatırımlarının iller arasında eşit bir biçimde dağıldığını ancak dönem boyunca katsayı değerlerinin yükselerek eşitsizliğin arttığını göstermektedir. 1999-2017 döneminde TRA, TRA1 ve TRA2 Bölgeleri için ortalama Gini Katsayısı değerleri sırasıyla 0.410, 0.433 ve 0.262 olarak hesaplanmaktadır. Bu durum üç bölge içerisinde kamu tarım yatırımlarının nispi olarak en eşit dağıldığı bölgenin TRA2 Bölgesi, en eşitsiz dağılan bölgenin ise TRA1 Bölgesi olduğunu göstermektedir. Gini Katsayısı ayrıştırma analizi sonuçlarına göre bölgeler arası eşitsizliğin toplam eşitsizliğe katkısının azaldığı, bölge içi eşitsizliğin ve örtüşmenin ise arttığı görülmektedir.
Türkiye'de Bal Arzı ve Talebi için Öngörü
Authors: SANER Gamze , ADANACIOĞLU Hakan , NASERI Zakiyeh
Published: August 2018

Günümüzde arıcılık tüm dünyada gelişmekte olan ve yapısal olarak tarımsal üretimin devamlılığını sağlayan önemli bir hayvancılık faaliyeti olup, bir tarım ülkesi olan Türkiye için de ayrı bir önem taşımaktadır. Türkiye 2016 yılında 7,900,364 adet kovan varlığı ile Dünyada 2. sırada, 105,727 ton bal üretimi ile 3. sırada yer almaktadır. Arıcılık, bal ve diğer arı ürünleri(polen, arı sütü, propolis, arı zehiri, balmumu) ile toplumun sağlıklı gelişimi açısından da önemli rol oynamaktadır. Bununla birlikte, Türkiye'de sürdürülebilir arıcılık ile ilgili stratejik planlama açısından bal arzı ve talebindeki gelecek eğilimlerini ortaya koymak önemli görülmektedir. Bu çalışmanın temel amacı 2016-2023 dönemi için Türkiye'deki bal arzı ve talebini öngörmektir. Bu çalışma ile arıcılık işletmelerinin gelecekte karşılaşabilecekleri durumları önceden öngörmeleri ve bu doğrultuda yatırımlarına yön vermeleri için bir fikir oluşturmaları amaçlanmıştır. Çalışmada yapılan öngörüler için Box-Jenkins tahmin modeli kullanılmıştır. Çalışmada elde edilen sonuçlara göre özellikle 2020 yılı sonrası bal arzı ve talebinde artış beklenmektedir. Bununla birlikte bal arzının talebi karşılamada yetersiz kalacağı öngörülmektedir.
Tarım Arazisi Kamulaştırmalarına İlişkin Üretici Görüş ve Beklentileri: Kocaeli Kandıra Gıda İhtisas Sanayi Bölgesi Örneği
Authors: AYDIN CAN Bahar , ENGİNDENİZ Sait
Published: August 2018

Bu araştırmada, Kocaeli'nin Kandıra ilçesinde kurulacak olan Kandıra Gıda İhtisas Organize Sanayi Bölgesinin (GİOSB) kamulaştırma sürecinde bölgedeki üreticilerin görüş ve beklentilerinin ortaya konulması amaçlanmıştır. Araştırmanın ana materyalini Kandıra ilçesinin Kocakaymaz ve Goncaaydın köylerinde faaliyet gösteren üreticilerden yüz yüze anket yöntemiyle elde edilen veriler oluşturmaktadır. Araştırmada köyde tarımla uğraşan ve görüşmeyi kabul eden Goncaaydın köyünden 47 üretici, Kocakaymaz köyünden ise 84 üretici olmak üzere, toplam 131 üretici ile tam sayım yöntemi kullanılarak anket yapılmıştır. Kandıra GİOSB'nin kurulması durumunda, arazisi kamulaştırılan 81 üreticinin %86.42'si, arazisi kamulaştırılmayan 50 üreticinin ise %90'ı bölgedeki tarım arazilerinin değerinin hızla artacağını düşünmektedir. Arazisi kamulaştırılan üreticilerin %79.01'inin belirlenen kamulaştırma bedelini kabul ettiği, %61.73'ünün kamulaştırılan arazilerinin yerine yer gösterilmesini istemediği ve üreticilerin yaş ortalamalarının yüksek olması nedeniyle üreticilik yapmayı düşünmemesinin bunda etken oluşturduğu saptanmıştır. Kamulaştırma sürecinde yaşanan anlaşmazlıklardan kaynaklı gecikmelerin ortadan kaldırılarak, Kandıra GİOSB'nin faaliyete geçmesinin sağlanması üreticilerin en fazla beklenti içinde oldukları konu olarak belirlenmiştir.