bluuebunny/crossref_metadata_2025 huggingface dataset:
Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2–Mediated Blood Pressure Reduction Independent of Cystogenesis
Authors: Lakshmipathi Jayalakshmi , Gao Yang , Hu Chunyan , Stuart Deborah , Genzen Jonathan , Ramkumar Nirupama , Kohan Donald E.
Published: April 2020

Significance Statement

Hypertension often occurs before renal function deteriorates in patients with autosomal dominant polycystic kidney disease (ADPKD), but it is unknown whether polycystin-1, the Pkd1 gene product, itself contributes to ADPKD hypertension. The authors examined this in mice with nephron-specific disruption of the Pkd1 gene without renal cysts. Compared with control mice, these knockout mice manifested reduced BP, enhanced natriuresis, decreased expression of Na+/K+/2Cl− cotransporter isoform 2 (NKCC2) protein, and increased urinary PGE2 excretion in response to a high salt diet. Blockade of cyclooxygenase-2 abolished the BP difference between Pkd1 knockout and control mice. These studies, apparently the first in vivo studies to describe a potential physiologic role for nephron polycystin-1, suggest that nephron polycystin-1 deficiency per se does not contribute to ADPKD-associated hypertension.

Background

Hypertension often occurs before renal function deteriorates in autosomal dominant polycystic kidney disease (ADPKD). It is unknown whether the Pkd1 gene product polycystin-1—the predominant causal factor in ADPKD—itself contributes to ADPKD hypertension independent of cystogenesis.

Methods

We induced nephron-specific disruption of the Pkd1 gene in 3-month-old mice and examined them at 4–5 months of age.

Results

Kidneys from the Pkd1 knockout mice showed no apparent renal cysts, tubule dilation, or increased cell proliferation. Compared with control mice, Pkd1 knockout mice exhibited reduced arterial pressure during high salt intake; this associated with an increased natriuretic, diuretic, and kaliuretic response during the first 2–3 days of salt loading. The lower arterial pressure and enhanced natriuresis during high salt loading in Pkd1 knockout mice were associated with lower urinary nitrite/nitrate excretion and markedly increased urinary PGE2 excretion, whereas GFR, plasma renin concentration, and urinary endothelin-1 excretion were similar between knockout and control mice. Kidney cyclooxygenase-2 protein levels were increased in Pkd1 knockout mice during high salt intake; administration of NS-398, a selective cyclooxygenase-2 inhibitor, abolished the arterial pressure difference between the knockout and control mice during high salt intake. Total kidney Na+/K+/2Cl− cotransporter isoform 2 (NKCC2) levels were greatly reduced in Pkd1 knockout mice fed a high salt diet compared with controls.

Conclusions

These studies suggest that nephron polycystin-1 deficiency does not itself contribute to ADPKD hypertension and that it may, in fact, exert a relative salt-wasting effect. The work seems to comprise the first in vivo studies to describe a potential physiologic role for nephron polycystin-1 in the absence of cysts, tubule dilation, or enhanced cell proliferation.
Incident Chronic Kidney Disease Risk among Hispanics/Latinos in the United States: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Authors: Ricardo Ana C. , Loop Matthew Shane , Gonzalez Franklyn , Lora Claudia M. , Chen Jinsong , Franceschini Nora , Kramer Holly J. , Toth-Manikowski Stephanie M. , Talavera Gregory A. , Daviglus Martha , Lash James P.
Published: April 2020

Significance Statement

Although the incident rate of ESKD is higher among Hispanics/Latinos living in the United States compared with non-Hispanics, less is known about incident rates of CKD. The authors report that this community-based prospective cohort study of more than 8000 Hispanics/Latinos in the United States found the overall rate of incident CKD to be 10.6 per 1000 person-years, with the highest rate observed among Puerto Ricans (15.0 per 1000 person-years). Important risk factors for new-onset CKD included elevated BP and glycated hemoglobin, as well as lower baseline eGFR and higher baseline albumin-to-creatinine ratio. Culturally tailored public heath interventions among Hispanics/Latinos focusing on prevention and control of risk factors, including diabetes and hypertension, might help decrease their burden of CKD and ESKD.

Background

Although Hispanics/Latinos in the United States are often considered a single ethnic group, they represent a heterogenous mixture of ancestries who can self-identify as any race defined by the U.S. Census. They have higher ESKD incidence compared with non-Hispanics, but little is known about the CKD incidence in this population.

Methods

We examined rates and risk factors of new-onset CKD using data from 8774 adults in the Hispanic Community Health Study/Study of Latinos. Incident CKD was defined as eGFR <60 ml/min per 1.73 m2 with eGFR decline ≥1 ml/min per 1.73 m2 per year, or urine albumin/creatinine ratio ≥30 mg/g. Rates and incidence rate ratios were estimated using Poisson regression with robust variance while accounting for the study’s complex design.

Results

Mean age was 40.3 years at baseline and 51.6% were women. In 5.9 years of follow-up, 648 participants developed CKD (10.6 per 1000 person-years). The age- and sex-adjusted incidence rates ranged from 6.6 (other Hispanic/mixed background) to 15.0 (Puerto Ricans) per 1000 person-years. Compared with Mexican background, Puerto Rican background was associated with 79% increased risk for incident CKD (incidence rate ratios, 1.79; 95% confidence interval, 1.33 to 2.40), which was accounted for by differences in sociodemographics, acculturation, and clinical characteristics. In multivariable regression analysis, predictors of incident CKD included BP >140/90 mm Hg, higher glycated hemoglobin, lower baseline eGFR, and higher baseline urine albumin/creatinine ratio.

Conclusions

CKD incidence varies by Hispanic/Latino heritage and this disparity may be in part attributed to differences in sociodemographic characteristics. Culturally tailored public heath interventions focusing on the prevention and control of risk factors might ameliorate the CKD burden in this population.
Biochips, aplicaciones convencionales e innovación: Una revisión documental
Authors: Rodríguez Sarmiento William Fernando , Vargas Vélez Juan Sebastián
Published: April 2020

Objetivo: Analizar las tendencias de la aplicación convencional de los biochips, para lo cual se realizó una revisión documental en torno a las tendencias en la creación de biochips a partir de una búsqueda y análisis de los trabajos publicados desde el año 2012 hasta el 2017 en la base de datos de la National Center for Biotechnology Information (NCBI). Resultados: Se encontró que las tendencias en la creación de biochips se han configurado como una innovación relativamente nueva en el campo de la Ingeniería Bioinformática aplicada en otras áreas, y en particular la medicina, para el tratamiento y diagnóstico de enfermedades como el cáncer. Asimismo, se encontró que desde la química y la genética se han desarrollado materiales para la fabricación de los biochips, haciéndolos biocompatibles para el organismo humano. Conclusiones: El desarrollo de nuevas tecnologías, usando biochips para la detección y monitoreo de enfermedades, permite la creación de tratamientos más efectivos y puntuales en pro de la salud y la calidad de vida. Así se evitan, además, complicaciones futuras de los pacientes, dado que su implementación sugiere una técnica menos traumática e invasiva.
Perception and confidence levels among dental students and interns in performing various endodontic procedures.
Authors:   Restorative and Prosthodontics department, college of dentistry, University of Science and Technology, Yemen. Department of conservative dentistry, Faculty of dentistry, Thamar University, Yemen., Madfa Ahmed A. , Senan Elham M. ,   Restorative and Prostho-dontics department, college of dentistry, University of Science and Technology, Yemen.
Published: April 2020

Aim: The present study aimed to collect information from senior students and new interns enrolled at the College of Dentistry, University of Science and Technology (UST), regarding their confidence levels in performing endodontic treatments. Materials and Methods: Anonymous surveys were distributed to 40 senior students and 37 new interns at UST, in Sana'a, Yemen. They were asked to indicate their self-confidence level using a Likert scoring system ranging from 1 and 5. Mann-Whitney U test and chi-squared test were used to determine statistical significance between the studied groups. Results: 37.5% of students and 35.1% of interns rated endodontic practice as difficult. Only 55% of students found that the number of treated cases were satisfactory, similar to that reported by interns (56.8%). There were no statistically significant differences between both groups regarding self-confidence levels for most endodontic procedures (p<0.05). Placing of a rubber dam, followed by managing inter-appointment flare-ups were procedures in which both groups reported the lowest confidence. On the other hand, both groups felt the lowest confidence in the treatment of maxillary followed by mandibular molars. Statistically significant differences were reported between the two groups for performing root canal treatments (RCT) (p< 0.05). Self-confidence levels on the management of most different indications showed no statistically significant differences between both groups (p>0.05) with exception to the management of irreversible pulpitis, necrotic pulp, asymptomatic apical periodontitis, chronic abscess, and traumatic cases, in which significant differences were noticed (p<0.05). Immature apices, root resorption, endodontic-periodontal (EP) lesions, trauma, symptomatic apical periodontitis and acute abscess were ranked as the cases in which both groups reported the lowest confidence. Canal blockage and ledge formation were the main mishaps encountered during practice among students and interns. Conclusion: Students and interns displayed neutral confidence in performing endodontic treatments.
Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome.
Authors:   School of Dentistry, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México., Martínez-Sandoval Gloria , Triana-Reyes Silvia ,   School of Dentistry, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México., Rodríguez-Franco Norma ,   School of Dentistry, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México., Chapa-Arizpe María ,   School of Dentistry, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México., Rodríguez-Pulido Jesús ,   School of Dentistry, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México., Alcázar-Pizaña Andrea ,   Centro de Investigación y Desarrollo en Ciencias de la Salud, Monterrey, Nuevo León, México., Riega-Torres Janett ,   Centro de Especialistas en Artritis y Reumatismo, Hospital Universitario. Monterrey, Nuevo León, México.
Published: April 2020

Sjögren's syndrome is a chronic autoimmune disease, characterized by the presence of hyposalivation and xerophthalmia, which in addition to other factors is diagnosed by the presence of rheumatoid factor in blood. The objective of the present study is to evaluate the presence of rheumatoid factor (IgG-IgM) in the saliva of patients with primary and secondary Sjögren's syndrome. Materials and methods: Forty samples from patients with primary and secondary Sjögren's syndrome previously diagnosed by the Arthritis and Rheumatism Specialist Center of the Autonomous University of Nuevo Leon were analyzed. Samples were taken from the saliva using the Carlson-Crittenden device to evaluate the IgG-IgM immunocomplex using the ELISA method. Results: No significant difference was found between the presence of IgM in primary (0.099±0.016) and secondary Sjögren syndrome (0.098±0.017), however, a high presence of IgG was found in the group of patients with secondary Sjögren's syndrome (0.134±0.054). Conclusion: The search for diagnostic tools using salivary biomarkers has come with economic and clinical advantages, however, in the present study no significant changes were found in salivary rheumatoid factor between both groups.
Pierre Robin Sequence: airway management via mandibular distraction. Case report
Authors:   Servicio de Cirugía Oral y Maxilofacial, Fundación Hospital Universitario Metropolitano. Barranquilla, Colombia., Arango Fernández Hernán , Rebolledo Cobos Martha ,   Departamento de Cirugía Oral, Universidad Metropolitana. Laboratorio de Genética Molecular, Universidad Simón Bolívar. Barranquilla, Colombia., Pineda Ovalle Saulo ,   Servicio de Cirugía Oral y Maxilofacial, Fundación Hospital Universitario Metropolitano. Barranquilla, Colombia., Harris Ricardo Jonathan ,   Departamento de Medicina Oral, Clínica Odontológica de la Corporación Universitaria Rafael Núñez. Cartagena, Colombia.
Published: April 2020

Pierre Robin sequence is a set of congenital conditions characterized by the presence of micrognathia, glossoptosis, cleft palate and obstruction of the airways. The latter can lead to many other complications such as respiratory difficulties, apnea, weight loss and even death. Currently, mandibular distraction, or the lengthening of the mandibular bone, is the most common surgical procedure used to correct a retracted tongue and the airway obstruction it produces in patients with mandibular hypoplasia. The present paper reports the case of a 26-day-old male patient, who presented obstruction on the upper respiratory tract, mandibular retromicrognathia, and retracted tongue and cleft palate, all conditions characteristic to Pierre Robin sequence. The patient also had a medical record of orotracheal intubation due to respiratory difficulties. The subject underwent mandibular distraction surgery with a horizontal vector, which resulted in a satisfactorily cleared airway.
Intraoral Acanthosis nigricans and its clinical relevance as a manifestation of a paraneoplastic syndrome: A case report
Authors:   Faculty of Dentistry, University of Chile, Santiago, Chile., Donoso-Hofer Francisca ,   Maxillofacial surgery Department, San Juan de Dios Hospital, Santiago, Chile., de la Maza-Acevedo Jaime ,   Faculty of Dentistry, University of Chile, Santiago, Chile.
Published: April 2020

Malignant-or-paraneoplastic acanthosis nigricans is a verrucous and hyperpigmented tumor affecting the mucosa and skin. In most cases malignant acanthosis nigricans is a distant manifestation of an intra-abdominal primary cancer. While the diagnosis of malignant acanthosis nigricans is challenging, some specific clinical and histopathological findings could lead to an accurate diagnosis. A rare clinical case of a 59-year-old female, who was referred to the maxillofacial surgery service due to a painful oral lesion in the palatine region, is presented. Upon examination, papillomatous lesions were observed on the hard palate, that were later diagnosed as intraoral malignant acanthosis nigricans secondary to gastric cancer. Both local and systemic evaluations are discussed, highlighting the relevance of a multidisciplinary approach consistent with the fact that these manifestations, although infrequent, should generate suspicion among clinicians and therefore motivation to perform a diligent and complete study since it can reveal the presence of a malignant pathology.
Land Suitability Determination of NPP’s Potential Site in East Kalimantan Coastal Using GIS
Authors: Susiati Heni , Sukadana I Gde , Budi Susilo Yarianto Sugeng , Yuliastuti Yuliastuti
Published: April 2020

Nuclear Power Plant (NPP) site selection is the key phase of the nuclear power plant process and significantly influence the construction cost and safety. In order to prepare for nuclear power programs in East Kalimantan province, Geographical Information System (GIS) analysis along the coast of East Kalimantan province, especially the Berau district, East Kutai, Kutai Kartanegara, Samarinda, Balikpapan, Penajam Paser Utara and the Paser. The research purpose is to find suitable site for nuclear power plants location using spatial analysis and modeling. The potential Nuclear Power Plant (NPP) site is based on several criteria, such as: geology, slope, soil type, land use, hydrology, and existing road network. Based on the weighting and ranking results using GIS application: there are three locations serve as the potential NPP sites are obtained Kutai Kartanegara and Kutai Timur regency. Next, land suitability analysis is done by using GIS application which shows potential sites suitable general and specific criteria of the site evaluation process development.
Studi Geologi Awal untuk Calon Tapak PLTN di Pulau Singkep dan Lingga, Kepulauan Riau
Authors: Indrastomo Frederikus Dian , Syaeful Heri , Anzhar Kurnia , Mellawati June
Published: April 2020

STUDI GEOLOGI AWAL UNTUK CALON TAPAK PLTN DI PULAU SINGKEP DAN LINGGA, KEPULAUAN RIAU. Pulau Singkep dan Lingga adalah bagian dari Kepulauan Riau, seperti Pulau Batam, Bintan, Karimun,terletak pada daerah strategis yang dapat menjadi lokasi dikembangkannya perdagangan dan perindustrian. Guna memenuhi kebutuhan teknologi dan listriknya, PLTN merupakan salah satu alternatif pilihan. Berdasarkan hal ini telah dilakukan studigeologi awal guna mengetahui keberadaan daerah interes untuk lokasi PLTN di Kepulauan Riau. Tujuan penelitian untuk mengetahui kelayakan Pulau Singkep dan Lingga dari aspek geologi sebagai daerah interes untuk ditindaklanjuti sebagai calon tapak PLTN. Metodologi penelitian meliputi studi geologi regional melalui pengumpulan data sekunder, dan survei lapangan untuk verifikasi data sekunder. Verifikasi data lapangan meliputi pengamatan batuan untuk menentukan jenis dan karakteristiknya, pengukuran struktur geologi untuk mengetahui potensi sesar dan gempa, pendataan sumber air panas untuk mengetahui aktivitas magmatisme. Pengamatan dilakukan di wilayah pesisir Pulau Singkep dan Lingga. Hasil penelitian awal untuk aspek geologi menunjukkan bahwa ditemukan beberapa daerah interes yang secara kualitatif merupakan lokasipotensial calon tapak PLTN. Dari aspek kegempaan, Pulau Singkep dan Lingga relatif aman. Sebaran batuan metamorfik dari Kompleks Malihan Persing dan granit Tanjungbuku ditemukan di Pulau Singkep, sedangkan sebaran batuan metamorf Formasi Tanjung Datuk di Pulau Lingga. Jenis batuan tersebut merupakankelompok batuan kerasdan resisten, sehinggasangat potensial untuk daerah interes calon tapak PLTN.
The calculation of gut metabolic modules form gene profile v1
Authors: Wang Qi
Published: April 2020

The calculation of gut metabolic modules form gene profile
Lightsheet Microscope Acquisition Protocol v1
Authors: Jorgensen Marda , Currlin Seth
Published: April 2020

The Zeiss Lightsheet 7 is used to quickly and efficiently scan large tissue volumes using laser lightsheet illumination. The focused laser sheets and imaging plane are static while the tissue is moved throughout the selected volume for three dimensional image acquisition. This protocol will cover the procedures used for the day of lightsheet image acquisition. Setting the acquisition volume: Large scanning volumes are composed of multiple z-stack being stitched back together based on overlapping edges of the scanning window. This requires setting an overall z-stack, which must include the entirety of tissue as covered by adjoining z-stacks. This becomes tricky when considering irregularly shaped tissues and their orientation relative to the various laser and imaging objectives. Dual-side lightsheet alignment: To obtain a strong and clear image from large tissues it is helpful to illuminate the sample with both the left and right laser. Each lasersheet can be angled slightly within the focal plane to account for differences in the R.I. of the tissue and R.I. media (TDE). This is a manual tuning process and is not intended for major R.I. differences. Protocol Overview: - Refractive index matching of cleared tissue samples. - Mounting tissue onto sample holder. - Image acquisition in Zen 3.1 LS (black edition), including: - Setting the acquisition volume - Dual-sided lightsheet alignment
PENGARUH LINGKUNGAN KERJA SOSIAL, KESELAMATAN DAN KESEHATAN KERJA TERHADAP KEPUASAN KERJA KARYAWAN PT KARYA YUSUP DI BANDUNG
Authors: Novianti Nesya , Senen Syamsul Hadi
Published: April 2020

Perkembangan industri manufaktur di Jawa Barat belakangan ini mengalami penurunan.Hal tersebut disebabakan akibat rendahnya kepuasan kerja para karyawannya, akibatnyaperusahaan sulit untuk mencapai tujuannya. Salah satunya yang mengalami kepuasankerja karyawan adalah PT. Karya Yusup di Bandung. Hal tersebut membuat PT. KaryaYusup menciptakan strategi untuk meningkatkan kepuasan kerja karyawan denganmeningkatkan lingkungan kerja sosial dan keselamatan dan kesehatan kerja. Penelitian inibertujuan untuk (1) mengetahui gambaran lingkungan kerja sosial, (2) mengetahuigambaran keselamatan dan kesehatan kerja, (3) mengetahui gambaran kepuasan kerja, (4)mengetahuipengaruh lingkungan kerja sosial terhadap kepuasan kerja karyawan, (5)mengetahuipengaruh keselamatan dan kesehatan kerja terhadap kepuasan kerja karyawandan (6) mengetahuipengaruh lingkungan kerja sosial dan keselamatan dan kesehatan kerjaterhadap kepuasan kerja karyawan PT. Karya Yusup di Bandung. Objek yang menjadiunit analisis dalam penelitian ini adalah karyawan PT. Karya Yusup di Bandung. Variabelbebas (X) dalam penelitian ini adalah Lingkungan kerja sosial dan keselamatan dankesehatan kerja, dan variabel terikat (Y) dari penelitian ini adalah kepuasan kerja. Jenispenelitian yang digunakan adalah deskriptif, verifikatif. Metode yang digunakan adalahexplanatory survey dengan teknik sampel yaitu teknik probability sampling denganjumlah sampel 83 responden. Teknik analisa data yang digunakan adalah regresi liniearbergandadengan alat bantusoftware komputer SPSS 20.0 for windows. Hasil temuan dalampenelitian ini menunjukkan bahwa gambaran lingkungan kerja sosial dalam kategori baik,gambaran keselamatan dan kesehatan kerja dalam kategori baik, gambaran kepuasan kerjadalam kategori baik, kepuasan kerja dipengaruhi secara positif oleh lingkungan kerja sosial,kepuasan kerja dipengaruhi secara positif oleh keselamatan dan kesehatan kerja, kepuasankerja dipengaruhi secara positif oleh lingkungan kerja sosial dan keselamatan dan kesehatankerja.Berdasarkan hasil penelitian ini direkomendasikan sebagai dasar untuk dilakukannyapenelitian lain mengenai lingkungan kerja sosial dan keselamatan dan kesehatan kerja denganindikator dan objek yang berbeda.
ANALISIS TINGKAT EFISIENSI BANK PERSERO DENGAN MENGGUNAKAN DATA ENVELOPMENT ANALYSIS (DEA) (Studi kasus pada Laporan Keuangan Bank Persero yang Terdaftar di Bank Indonesia Periode 2004-2013 )
Authors: Apriadi Tedi , Nugraha Nugraha
Published: April 2020

Penelitian ini bertujuan mengukur tingkat efisiensi bank persero periode tahun 2004-2013 dengan menggunakan metode Data Envelopment Analysis (DEA), dengan softwere BANXIA. Pendekatan yang digunakan dalam memilih input dan output adalah pendekatan intermediasi. Faktor Input yang digunakan adalah aset, deposito dan beban personalia. Faktor output yang digunakan adalah kredit dan pendapatan operasional lainnya. Hasil penelitian diperoleh bahwa (1) penggunaan input aset, deposito dan beban personalia rata-rata meningkat. Dan penggunaan output kredit dan pendapatan operasional lainnya juga rata-rata meningkat. (2) Penggunaan input dan output bank persero dari tahun 2004-2013 dengan menggunakan DEA belum mencapai efisiensi optimum. Model Variable Return To Scale lebih baik dari pada model Constan Return To Scale. (3) Efisiensi skala bank persero dengan metode DEA berada pada tahap Decreasing  Return to Scale. Dalam keadaan demikian, dapat diartikan bahwa proporsi penambahan input akan menghasilkan tambahan output yang proporsinya lebih kecil. Kata Kunci : Efisiensi, DEA, Bank Persero.
PELAKSANAAN SERVICE EXCELLENCE BADAN USAHA BPJS KESEHATAN KCU BANDUNG
Authors: Rismayanti Rosi , Hurriyati Ratih
Published: April 2020

Tujuan  – Tujuan dari penelitian ini adalah untuk mengetahui gambaran pelaksanaan service excellence BPJS Kesehatan KCU BandungDesain/Metodelogi/Pendekatan  – Objek penelitian makalah ini adalah peserta Badan Usaha BPJS Kesehatan KCU Bandung dengan sampel 100 perusahaan. Menggunakan analisis deskriptif.Temuan – Perolehan skor pada variabel service excellence yaitu sebesar  81,6% sehingga dapat dikatakan bahwa service excellence BPJS Kesehatan KCU Bandung badan usaha telah sesuaiKeterbatasan  – Penelitian kali ini memiliki pembatasan masalah seputar pelayanan pembuatan kartu peserta JKN yang dilakukan oleh BPJS Kesehatan. Pelayanan rumah sakit tidak termasuk dalam penelitian ini.Originalitas/Nilai – Penelitian ini membahas mengenai pelaksanaan service excellence pembuatan kartu badan usaha jaminan kesehatan sosial yang dilakukan BPJS Kesehatan di Indonesia khususnya di Bandung. Kata Kunci Service Excellence, Jaminan Kesehatan Sosial, Badan Usaha, Layanan Pembuatan KartuTipe Penelitian  Research paper
DAMPAK LINGKUNGAN KERJA SOSIAL DAN INSENTIF PADA SEMANGAT KERJA KARYAWAN INDUSTRI PARIWISATA
Authors: Nugroho Muhammad Rizal , Senen Syamsul Hadi , Tarmedi Eded
Published: April 2020

Tujuan penelitian - Tujuan dari makalah ini adalah untuk mengetahui dampak lingkungan kerja sosial dan insentif pada semangat kerja karyawan industri pariwisata.Model/metode penelitian/pendekatan – Model penelitian ini memakai model cross- sectional. Penelitian ini menggunakan pendekatan deskriptif dan verifikatif dengan metode survei. Sebanyak 84 responden dipilih sebagai simple random sampling. Survei menggunakan instrumen penelitian berupa kuesioner untuk mengumpulkan data dari responden. Teknik analisis data yang digunakan dalam penelitian ini memakai regresi linier.Temuan penelitian – Terdapat hasil positif mengenai dampak lingkungan kerja sosial dan insentif pada semangat kerja karyawan industri pariwisata.Orisinalitas/Nilai – Penelitian ini mengangkat permasalahan bagaimana cara peningkatan semangat kerja karyawan melalui lingkungan kerja sosial dan insentif. Perbedaan penelitian ini dengan penelitian sebelumnya pada objek yang digunakan, variabel yang digunakan, mendukung teori serta referensi yang berbeda yang digunakan oleh peneliti sebelumnya.Kata kunci: Dampak lingkungan kerja, lingkungan kerja sosial, insentif, semangat kerja, industri pariwisata.Jenis Jurnal: Artikel Penelitian
PENGARUH KUALITAS INFORMASI TERHADAP KEPUTUSAN PEMBELIAN SECARA ONLINE YANG DIMEDIASI OLEH KEPERCAYAAN KONSUMEN (Survei pada Pengguna E-commerce di Indonesia)
Authors: Ferdiansyah Gerry , Rahayu Agus
Published: April 2020

Tujuan - Seberapa besar pengaruh kualitas informasi terhadap keputusan pembelian online, pengaruh kualitas informasi terhadap kepercayaan konsumen dan kepercayaan konsumen terhadap keputusan pembelian secara online.Desain/Metodologi/Pendekatan - Jenis penelitian yang digunakan adalah deskriptif, verifikatif, dengan jumlah sampel sebanyak 153 pengguna. Teknik analisa data yang digunakan adalah analisis jalur.Temuan - Dari penelitian terhadap pengujian hipotesis dapat diketahui bahwa kualitas informasi terhadap keputusan pembelian memiliki pengaruh positif dengan kategori sangat rendah, kualitas informasi terhadap kepercayaan konsumen memiliki pengaruh positif dengan kategori besar, kepercayaan konsumen terhadap keputusan pembelian secara online memiliki pengaruh positif dengan kategori sedang.Orisinalitas – Perbedaan ditemukan dalam periode penelitian, teknik analisis, alat ukur dan hasil penelitian. Penulis juga menambahkan teori dari jurnal asing dan buku asing Kata kunci: kualitas informasi, kepercayaan konsumen, keputusan pembelian secara onlineTipe artikel: penelitian
STRUKTUR MODAL TERHADAP ECONOMIC VALUE ADDED PADA PT PRIMARINDO ASIA INFRASTRUCTURE TBK TAHUN 2001-2015
Authors: Muthahhari Muhammad Husain , Purnamasari Imas , Sulastri Sulastri
Published: April 2020

Purpose - This study was conducted to look at the capital structure and economic value addedDesign / methodology / approach -The method of this research using and verification.. The object of this research is PT Primarindo Asia Infrastructure Tbk. Data collection techniques with time series. Data analysis techniques using multiple analysis techniques that is with the help of SPSS 20 for windows.Findings - Based on the results of research using verifikatif analysis, obtained the result that the capital structure does not have a positive effect on economic value added which means if there is a change in capital structure will affect with the increase of economic value addedOriginality / value - This research provides a basis for understanding the issues of capital structure overview and Economic value added. The difference of this research with the previous research is located on the object which is the company in the manufacturing industry that is PT Primarindo Asia Infrastructure Tbk with the variables studied are capital structure, and economic value added, and using theory or reference different from previous researchers. The results of this study that the structure of the capital in the nose using debt to equity ratio has a negative result
ANALISIS PELATIHAN, PEMBERDAYAAN DAN KEPUASAN KERJA PEGAWAI DI PT BANK RAKYAT INDONESIA KANTOR CABANG KUNIINGAN
Authors: Putri Wulan Dewani , NURYANTI B LENA , Masharyono Masharyono
Published: April 2020

Purpose - The purpose of this study is to analyze empowerment training and job satisfaction.The design / methodology / approach - The design of this study was cross sectional. This research uses descriptive approach with explanatory survey method. The employee analysis unit is 50 people. Data collection using questionnaire. The analysis technique used is descriptive technique by using frequency distributionFindings – Based on the results of research using descriptive analysis, the results obtained that training in the good category, empowerment in the good category, and job satisfaction in the high category.Originality - This study provides a basis for understanding the issues of the training and empowerment on job satisfaction. The difference of this research with previous research is on the object in PT. Bank Rakyat Indonesia Kuningan branch office, training variable, empowerment and job satisfaction, and references used by researchers with previous researchers.
GAMBARAN PENERAPAN NET PROFIT MARGIN DAN EARNING PER SHARE TERHADAP HARGA SAHAM PADA SUB SEKTOR PERUSAHAAN INVESTASI PADA TAHUN 2011-2016
Authors: Nuurohman Fajar , Tarmedi Eded , Mayasari Mayasari
Published: April 2020

Objectives - The purpose of this study is to find out how the picture of the application of net profit margin and earnings per share to stock prices in the sub-sector of investment companies in 2011-2016design / methodology / approach - The method used in this research is descriptive and verifikatif method. The data used are secondary data from each company sub sector of investment company in year 2011-2016 with analysis technique using multiple regression. Sampling in this research use purposive sampling.Findings - The results of this study indicate that, the application of net profit margin effect on stock prices. earnings per share effect on stock prices. The results showed that the application of net profit margin and earnings per share a positive influence on stock prices.Originality - Differences of research with previous research is on the object, population and sample research, the study period, measuring instruments and research results, as well as sources of foreign theories and journals and foreign books and research results
Analisis Kondisi Lingkungan Kerja dalam Meningkatkan Employee Engagement pada Karyawan Bagian Produksi Industri Manufaktur di Cimahi
Authors: Gunawan Riki , Senen Syamsul Hadi , Tarmedi Eded
Published: April 2020

Employee engagement is one of the main issues in human resources management and organizations, because it is considered as a major factor in measuring the strength of a company. Issues regarding employee engagement occur in various industries, including manufacturing. It's like what happened to PT. Pola Manunggal Sejati Cimahi, low indicator of employee engagement can be seen from high employee turnover, increased absence, and production targets that have decreased every year, so that the resulting production especially in the year 2016-2018 did not achieve the targets set by the company. This research uses descriptive and verification method, with explanatory survey method. The sampling technique used is probability sampling using the simple random sampling which amounted to 81 people. Data analysis technique used is simple linear regression with program tools SPSS (Statistical Product for Service Solution) 25.0 for Windows. The results of this study indicate that the description of the work environment in good category, description of the employee engagement in high category, and the employee engagement is affected by the work environment. So that the work environment should be considered in support of improving employee engagement.
Faktor pembelajaran kewirausahaan dan motivasi berwirausaha dalam meningkatkan niat berwirausaha
Authors: Hafizhah Khansa , Mulyadi Hari , Utama R Dian H
Published: April 2020

Abstract: The main goals of this study is to derive the positive effect of entrepreneurial learning on entrepreneurial intentions, the effect of entrepreneurial motivation on entrepreneurial intentions, and the combined influence of entrepreneurial learning and entrepreneurial motivation on entrepreneurial intentions.  This study has been performed using a group of students from the Bandung City Vocational egvtechnique used was a questionnaire with a sample size of 107 respondents.  The results of this study found that the influence of entrepreneurial learning on entrepreneurial intentions belonged to the strong category, motivational motivation influenced the intention of entrepreneurship included in the strong category, and entrepreneurial learning and entrepreneurial motivation influenced the intention of entrepreneurship, including in the strong category.  (In this study it is found, if the picture of entrepreneurial learning was effective, it would increase the intention of student entrepreneurship.)  The high motivation of student entrepreneurship will create a high intention of entrepreneurship.  In addition, if entrepreneurial learning is effective and coupled with a high motivation for entrepreneurship, the intention of student entrepreneurship will increase.
Perilaku Herding Di Pasar Saham: Sebuah Kajian Literatur
Authors: Ningtyas Regina Aulia
Published: April 2020

Artikel ini bertujuan untuk membuktikan keberadaan perilaku herding di sejumlah pasar saham di berbagai belahan dunia dan mengetahui faktor-faktor penyebab perilaku herding. Metode yang digunakan dalam artikel ini adalah perpustakaan penelitian dengan mengambil data dari 80 jurnal internasional dan 4 jurnal lokal. Hasil analisis kami menyimpulkan bahwa perilaku herding terjadi di hampir semua pasar saham di dunia. Faktor-faktor yang menyebabkan perilaku herding meliputi sentimen berita negatif terhadap saham, insentif dan kekhawatiran karier yang dimiliki oleh analis, risiko pasar dan ketidakpastian tingkat perusahaan, ketidakpastian pasar, kondisi pasar ekstrem, periode arus informasi tinggi, risiko volatilitas, analisis jenis saham yang lebih kecil, terjadinya krisis ekonomi/keuangan, kondisi pasar yang menurun, kenaikan suku bunga, depresiasi mata uang, lingkungan informasi yang buruk, dan pengungkapan berkualitas rendah. Keterbatasan artikel ini adalah jumlah data yang diambil dari hasil penelitian di beberapa pasar saham tidak merata, seperti kurangnya pengambilan data dari pasar saham di benua Amerika.
The Features of Floristic Composition and Community Structure of the Birch Forests in the Forest-to-Bog Ecotones in the South of the Vasyugan Plain
Authors: Klimova Nina V. , Chernova Natalia A. , Nikiforov Art’em N. , Dyukarev Anatoliy G.
Published: April 2020

The present study addresses the floristic composition and ecological and community structure of paludified birch forests (peat depth reaching 30 cm) in the southern taiga. The growing conditions were evaluated based on the indicator values of plants and soil chemical properties. The study plots were located on transects directed from upland forests through peripheral wetland forests to bogs, which are situated in topographic lows, at the North-East edge of the Great Vasyugan mire. The sites of the forest-to-bog ecotone that are transformed to various degrees by the bog water regime are considered as successive stages of paludification. Because of the high carbonate content of the soil-forming rocks dominated by heavy clay particles and waterlogging by ground-mire waters, wet green forests without a developed moss cover form here on rich peat-humus soils at the initial stages of hydromorphic transformation of the plant community. This is in contrast to typical plant successions, which develop on carbonate-free sediments and whose development is associated with the effect of acid bog waters. Reed grass (Calamagrostis phragmitoides C. Hartman) dominates the ground vegetation, which also includes sedges (Carex canescens L., C. vaginata Tausch., C. disperma Dew.). The high contents of mineral nutrients in organics-accumulating dark humus soils determines the high floristic diversity of paludified birch forests, comparable with the diversity of upland communities. A significant part of the ground cover of these forests (25% of the species composition, up to 50% of the projective cover) is represented by nutrient-demanding forest- and meadow-swamp plant species, which commonly occur in eutrophic boreal forested swamps of West Siberia with groundwater input. These species are absent in the mesotrophic paludified taiga forests. At a later stage of hydromorphic transformation, pine-birch shrub-moss forests form on peat-humus-gley and peat-gley soils. As the nutrient availability of soils declines, the number of plant species decreases, and plant species with lower nutrient requirements begin to predominate. This leads to the ecological restructuring of wet communities and makes them similar to paludified forests on carbonate-free sediments; peat accumulation begins with the deposition of mesotrophic peat. Thus, a more substantial change occurs in the ecological structure of plant communities on high-carbonate clays during their hydromorphic transformation compared to the typical mesotrophic paludification of dark-coniferous forests on loams
The Contents and Distributions of Natural Radionuclides 238U, 232Th, 40K in Permafrost Soils of Central Yakutia
Authors: Chevychelov Alexander P. , Sobakin Peter I.
Published: April 2020

The present study addresses the contents and distributions of natural radionuclides 238U, 232Th, and 40K in six main types (subtypes) of soils that have developed in friable alluvial sandy deposits within various layers of the topography of the Central Yakutian Plain. The minimum concentrations of these radionuclides are registered in forest soils of the eluvial type that have developed on weathered sandy deposits of the high level, whereas the maximum concentrations are detected in forest pale-yellow and meadow-steppe soils that have developed on loess-like carbonate loams of the middle level and in polymictic sands of the lower level of the plain, respectively. In addition to the structure of soil forming rocks, the soil formation processes in these soils, such as humus accumulation, podsolization, bleaching, and intra-soil clay deposition have a significant effect on the contents and distributions of 238U, 232Th, and 40K. In the soils examined in this study, 40K distribution followed the eluvial and uniform patterns, whereas the intra-profile distribution of 238U and 232Th was more variable, following the accumulative, eluvial, accumulative eluvial, accumulative eluvial-illuvial, and accumulative illuvial patterns. We have revealed statistically significant correlations between 238U and 232Th contents and soil contents of humus, clay, and silt
Study of Structural and Catalytic Properties of Pt/WOх/ZrO₂, Modified by Lanthanum Cations
Authors: Naumova Svetlana A. , Obukhova Anastasia V. , Kuznetsova Ludmila I.
Published: April 2020

The effect of the addition of La3+ cations on the structural properties of Pt/WOх/ZrO₂ catalysts and the characteristics of catalytic activity in the process of hydroisomerization of n-heptane and benzene mixture was studied. The phase composition of the catalysts is represented by a solid solution of lanthanum cations in nanocrystalline zirconia of tetragonal modification with localization of lanthanum in the surface layers predominantly. The positive effect of La3+ additives on the selectivity and yield of isomerized products was shown
Synthesis and Study of Copper-Containing Polymers Based on Sulfated Ethanol Lignin of Abies Wood
Authors: Vasilyeva Natalia Yu. , Levdansky Alexander V. , Kazachenko Alexander S. , Maximov Nikolai G. , Skvortsova Galina P. , Lutoshkin Maxim A. , Korol’kova Irina V. , Kuznetsov Boris N.
Published: April 2020

For the first time water soluble copper-containing polymers based on sulfated ethanol lignin of abies wood were obtained by the method of ion exchange. Their composition and structure were studied with the use of elemental and chemical analysis, infrared spectroscopy (IR), atomic absorption, electron paramagnetic resonance (EPR). The absence of nitrogen for copper cations in the resulting polymer indicates the complete substitution of ammonium cations in the ammonium salt of sulfated ethanol lignin. In EPR spectrum of copper-containing sulfated ethanol lignin there is a superposition of two signals. One of them belongs to isolated Cu2+ ions, the other to exchange-bound Cu2+ ions in salt-like compounds. The integral intensity of signal of isolated Cu2+ ions (anisotropic signal) and exchange-bound ions (isotropic signal) depends on the copper content in the polymer
The Emergence of Native Podcasts in Journalism: Editorial Strategies and Business Opportunities in Latin America
Authors: Rojas-Torrijos José Luis , Caro-González Francisco Javier , González-Alba José Antonio
Published: April 2020

This article analyses the state of the art of podcasting in the new digital landscape as well as the structures, editorial strategies, and business models of native podcasts launched in Latin America over the last few years. To this end, a multiple case study has been made to examine the way new digital outlets are using audio content. This qualitative research is made up of a variety of approaches, such as interviews, online surveys of podcasters, as well as the collection and analysis of secondary data. A specific aim of this comparative study was to include a sample of podcasts produced by thirteen emerging media platforms from eight countries registered in the directory of digital natives conducted by SembraMedia (https://www.sembramedia.org). This is a nonprofit organization dedicated to increasing the diversity and quality of Spanish language content by helping digital media entrepreneurs become more sustainable and successful. Results of this exploratory study reveal that native podcasting in Spanish is still expanding and that where the new media are small in scale, they are more oriented to the full exploitation of the narrative and innovative possibilities of this audio format and do not have responding to their target audiences’ needs as their main priority. These new media are finding different ways to become monetised (mainly content production for clients, sponsored content, sponsorship, consulting services, and advertising) and to make a profit.
Behind the Comments Section: The Ethics of Digital Native News Discussions
Authors: Castellano Parra Orge , Ayerdi Koldobika Meso , Fernández Simón Peña
Published: April 2020

Initially offered as a digital public sphere forum, comments sections became the preferred democratic arena for gatekeepers to encourage their readers to engage in constructive dialogue about relevant issues. However, news sites require commenters to remain civil in their interactions, which led users to seek alternative ways of commenting on the news. This article explores in-depth the contents of a sample of 98,426 user-comments collected between February–March 2019 from three major Spanish digital native newspapers: ElDiario.es, ElEspañol.com, and ElConfidencial.com. The main goals were to analyze whether comments in news outlets are deliberative, to assess the quality of the debate that takes place in them, and to describe their specific features. Discourse ethics were explored to determine the discussions’ impact, the language used, the acceptance of arguments, and the recognition and civility of participants. Findings reveal that comments sections in news outlets do not have a dialogic nature and that the debates have a low-quality profile. Nonetheless, the degree of mutual respect in interaction is acceptable, with slightly observed levels of incivility. Finally, the data suggest that the focused comments are higher on social media and that memes and emojis represent a new form of digital discourse.
Journalism Expands in Spite of the Crisis: Digital-Native News Media in Spain
Authors: Negredo Samuel , Martínez-Costa María-Pilar , Breiner James , Salaverría Ramón
Published: April 2020

Digital-native news organizations have grown steadily in Spain since the mid-1990s and they have become established as a major force in the media market. Paradoxically, their biggest expansion coincided with the Great Recession (2008–2014). In fact, their numbers increased most during 2012–2013, when traditional media were cutting staff in response to the economic crisis, and unemployment rates in the media sector as a whole hit their peak. However, these digital-native news startups have yet to prove their sustainability and stability. This study uses our own database of 3,862 native and non-native digital news outlets in Spain and the Reuters Institute Digital News Report to analyze a number of characteristics of these media, such as the percentage that have gone inactive, the relative popularity of legacy brands vs. digital natives, multi-platform synergies, content subject matter, geographical location, ownership, and funding sources. Based on these quantitative parameters, this study reviews the structural strengths and weaknesses of digital-native media in the Spanish news market. Taking into account these findings, we conclude that the surge in digital-native news media observed in Spain during the Great Recession followed the pattern of creative destruction described by several economists.
“A Educação é a porta para tudo”: O valor da educação para o assentamento Florestan Fernandes
Authors: Santos José Wilson Moura , Santos Cleones Gomes dos
Published: April 2020

RESUMO: Este artigo é produto das discussões da disciplina “Tópicos especiais em Ensino de História” ministrada pelos professores-doutores Paulo Heimar Souto e Joaquim Tavares e da “Visita Técnica ao Assentamento Florestan Fernandes”. Esta disciplina se pautou no estudo da História Oral, a exemplo de Chiozzini (2007), Pollak (1992), Nora (2012), Thompson (1952) entre outros e, na visão de educação defendida por Freire (2019) e Perrenoud (2002), os quais abordamos neste texto. Temos como objetivo demonstrar como esses estudos nos levaram a conhecer o Assentamento Florestan Fernandes, e a partir da História Oral buscar conhecer a História de vida que emerge das narrativas, das vivências e experiências de alguns assentados. Como procedimento metodológico realizamos uma visita de observação em locus e entrevista com uma pessoa da localidade. Por fim, percebemos o quanto a educação é de fato um instrumento para mudanças que ultrapassam os limites da formalidade institucional.

PALAVRAS-CHAVE: História Oral, Narrativa, Aprendizagem.