bluuebunny/crossref_metadata_2025 huggingface dataset:
A National Education Service for Adults Too
Authors: Todd Nigel , Tuckett Alan
Published: July 2019

This article highlights the current collapse of adult learning opportunities and the key importance of adult learning to a new public education in a fast-changing world, and makes practical proposals for Labour's National Education Service.
Making a Co-operative University: a new form of knowing – not public but social
Authors: Neary Mike , Winn Joss
Published: July 2019

Calls to establish public education avoid the fact that public education is provided by the capitalist state whose real purpose is the market-based model of private gain. Public against private education is a false dichotomy; rather, public and private are complementary forms of capitalist
regulation. Radical alternatives require a more foundational critique of the structures of capitalist education, grounded in an understanding of the contradictory relationship between capital and labour on which the institutions of capitalist civilisation are based. This article suggests a
counter project: not public education but social knowing as the basis for a solidaristic form of social life. Our model for social knowing starts with the idea of a co-operative university.
Pan-Cancer Analysis of CDK12 Loss-of-Function Alterations and Their Association with the Focal Tandem-Duplicator Phenotype
Authors: Sokol Ethan S. , Pavlick Dean , Frampton Garrett M. , Ross Jeffrey S. , Miller Vincent A. , Ali Siraj M. , Lotan Tamara L. , Pardoll Drew M. , Chung Jon H. , Antonarakis Emmanuel S.
Published: July 2019

Background

CDK12 loss-of-function (LOF) genomic alterations are associated with focal tandem duplications (FTDs) in ovarian and prostate cancers. Because these FTDs may produce fusion-induced neoantigens (FINAs), CDK12 alteration is a candidate biomarker for immune checkpoint inhibitor sensitivity. Here we determine the prevalence of CDK12-LOF alterations and their association with FTDs across diverse tumor types.

Materials and Methods

A total of 142,133 tumor samples comprising 379 cancer types were sequenced (August 2014 to April 2018) by hybrid capture-based comprehensive genomic profiling (Foundation Medicine, Cambridge, MA) as part of routine clinical care. Results were analyzed for base substitutions, short insertions/deletions, rearrangements, and copy number alterations. CDK12-LOF genomic alterations were assessed for zygosity status and association with FTDs/focal copy number gain.

Results

CDK12 genomic alterations were detected in 1.1% of all cases, most frequently in prostate cancer (5.6%), but were also observed at >1% frequency in 11 cancer types. Across multiple cancer types, including prostate, gastric/esophageal, ovarian, breast, and endometrial cancer, the number of FTDs was significantly increased in CDK12-LOF versus CDK12 wild-type cases. Notably, CDK12-LOF was not consistently associated with a homologous recombination deficiency genomic signature. Quantitative assessment of CDK12-associated FTDs by measurement of single copy number gains identified novel likely deleterious CDK12 kinase-domain mutations in prostate and ovarian cancers.

Conclusion

Detection of CDK12-LOF genomic alterations and their association with FTDs in a diverse spectrum of malignancies suggests that immunotherapy approaches targeting FINAs derived from CDK12-associated FTDs may be a broadly applicable strategy that could be explored across cancer types in a tumor-agnostic manner.

Implications for Practice

CDK12 inactivation in ovarian and prostate cancer results in the generation of focal tandem duplications, which can cause fusion-induced neoantigens. In prostate cancer, CDK12 alterations have demonstrated promise as a potential predictive biomarker for response to immune checkpoint blockade. This study evaluated genomic profiling data from >142,000 tumors to determine the prevalence of CDK12 loss-of-function genomic alterations across tumor types and demonstrated that CDK12 alterations are associated with the tandem-duplicator phenotype in cancer types other than ovarian and prostate cancer. The association of CDK12 alterations with focal tandem duplications across broad cancer types suggests that CDK12 inactivation warrants further investigation as a pan-cancer biomarker for immunotherapy benefit.
Perfil e conhecimento de gestantes sobre o diabetes mellitus gestacional
Authors: Morais Amanda Moreira de , Rempel Claudete , Delving Luciana Knabben de Oliveira Becker , Moreschi Claudete
Published: July 2019

Justificativa e Objetivos:O diabetes mellitus gestacional (DMG) é o distúrbio metabólico que determina redução da tolerância à glicose,
diagnosticado na gestação, que pode ou não se perpetuar após o parto. No Brasil, em torno de 7% das gestações são complicadas pela
hiperglicemia gestacional. O presente estudo teve como objetivo avaliar o perfil epidemiológico, socioeconômico, clínico-obstétrico e
identificar o conhecimento em relação ao DMG de gestantes atendidas em um Centro Especializado de Saúde da Mulher de uma Unidade
Básica de Saúde (UBS) de Lajeado/RS. Métodos:A metodologia consistiu na aplicação de três questionários: avaliação do perfil socioeco-nômico, epidemiológico e clínico-obstétrico; avaliação do conhecimento sobre DMG; e, avaliação do conhecimento das gestantes sobre
diabetes. Participaram da pesquisa 20 gestantes atendidas na UBS no período de 15 de abril a 15 de maio de 2017. As informações foram
tabuladas em planilha do Excel, sendo que as variáveis quantitativas foram descritas através de frequência absoluta e relativa e foi seguida
a sintaxe prevista para análise doDiabetes Knowledge Questionnaire(DKN-A). Resultados:Os resultados mostraram que as grávidas
não possuíam conhecimento sobre diabetes, embora 90% tenham afirmado possuir informação e atualização sobre temas de saúde. A
maioria das gestantes era branca, natural de Lajeado, casada ou em união estável, com renda mensal de até três salários mínimos, 85%
tinha entre 15 e 35 anos e 50% possuía ensino fundamental. A maioria (90%) não tinha doença prévia à gestação, 55% utilizava medicação
durante a gestação, 65% não praticava atividade física e 65% não consultou nutricionista nos últimos 12 meses. Nenhuma das gestantes
possuía Diabetes Mellitus ou teve DMG em gestação prévia, contudo uma participante (5%) apresentava DMG. Conclusão:Conclui-se
que as gestantes com faixa etária de 15 a 35 anos, entrevistadas na UBS de Lajeado, desconheciam os riscos ou os cuidados necessários
na gestação para evitar o DMG.
Descritores: Endocrinologia. Gravidez. Hiperglicemia
Epidemiological overview of chagas disease in the state of Amazonas, from 2004 to 2014
Authors: Menezes André Luiz Rodrigues , Oliveira Gerlandes Fernandes de , Ribeiro Mariane Albuquerque Lima , Castro Gabriela Vieira de Souza , Lima Renato Abreu , Meneguetti Dionatas Ulises de Oliveira
Published: July 2019

Justificativa e Objetivos: A doença de Chagas (DC), causada pelo Trypanosma cruzi, protozoário flagelado, descoberto a mais de 100 anos, sendo ela difundida nas américas, principalmente na américa do Sul, acometendo milhões de pessoas pelo mundo. É cada vez mais crescente o número de indivíduos acometidos com a DC na região da Amazônia Ocidental e estão relacionados a diversos fatores, porém o consumo de bebida contaminada é a principal parcela de contribuição para a elevação nos registros da doença na região. Este estudo tem como objetivo descrever e analisar o panorama epidemiológico da doença de Chagas no estado do Amazonas de 2004 a 2014. Métodos: Trata-se de um estudo ecológico, onde foram utilizados somente dados secundários obtidos do Sinan referentes aos casos notificados de infecção por T. cruzi em todo o estado do Amazonas. Resultados: Constatou-se que no período de 2004 a 2014 que no estado do Amazonas ocorreram um total de 100 casos de DC, tendo maior ocorrência nos anos de 2007 e 2010, durante os meses de abril e dezembro, com maior frequência da faixa etária de 20-39 e no gênero feminino. Conclusão: Constatou-se a necessidade de implementar um serviço de controle epidemiológico eficaz para monitoramento da via de transmissão DC e de seus vetores, pois trata-se de um problema de saúde pública que pode estar ligada a determinantes sociais e culturais, sendo indicado a promoção de atividades educativas para a conscientização da comunidade a respeito desta enfermidade. Descritores: Epidemiologia. Tripanossomíase Americana. Amazônia
Adesão às medidas preventivas versus incidência de pneumonia associada à ventilação mecânica
Authors: Silva Lourençone Emerson Matheus , Branco Aline , Baptista Monteiro Ariane , Petittembert Fonseca Jaqueline , Aquino Caregnato Rita Catalina
Published: July 2019

Justificativa e Objetivos:Pneumonia associada à ventilação mecânica (PAV) é a infecção relacionada à assistência à saúde que mais
acomete pacientes em ventilação mecânica internados na unidade de terapia intensiva (UTI), sendo necessárias medidas de prevenção
para garantir a assistência segura. Objetiva-se avaliar a taxa de adesão das ações preventivas da equipe de enfermagem para PAV, após
a reestruturação e aplicação do protocolo de prevenção e verificar as taxas de densidade de incidência de pacientes com PAV. Métodos:
Estudo observacional, longitudinal de análise de adesão ao bundleapós reestruturação, realizado em UTI geral de adultos, entre maio e
novembro de 2017. Amostra por conveniência com 154 pacientes em ventilação mecânica. Avaliados cuidados de enfermagem: higiene
oral com clorexidina 0,12%; cabeceira elevada; pressão do cuff; e posição do filtro. A intervenção foi reforço contínuo da equipe para a
realização das medidas preventivas. Serviço de Controle de Infecção calculou taxas de PAV mensalmente para comparação. Resultados:
A média da taxa de adesão das medidas preventivas em 1.296 avaliações realizadas evidenciou adequação em: 94% posição do filtro;
88,7% cabeceira elevada; 77,3% higiene oral com clorexidina 0,12%; e 91,7% controle da pressão do cuff. Conclusão:Com monitorização
e reforço contínuo, as medidas preventivas para PAV, realizadas pela equipe de enfermagem, mantiveram-se acima dos 77%, com a
concomitante diminuição na taxa de PAV.
Descritores: Pneumonia associada à ventilação mecânica. Infecção hospitalar. Unidades de terapia intensiva. Cuidados críticos
LA MISIÓN DE LA IGLESIA EN EL MARCO DEL GRAN CONFLICTO
Authors: Varela Christian
Published: July 2019

La misión de Dios en el contexto del discipulado es el imperativo para los creyentes de hoy. Diversos enfoques han propuestos perspectivas variadas para la misión de la iglesia. El gran conflicto entre Cristo y Satanás esclarece la naturaleza de la misión comisionada a su pueblo de todos los tiempos. Por tanto, este estudio analiza la misión de la iglesia en el marco del gran conflicto y sus respectivas implicancias misionológicas.
DANIEL Y APOCALIPSIS: SU IMPORTANCIA PARA EL SIGLO XXI
Authors: A. Jaimes Nhilo , Iparraguirre Joel
Published: July 2019

Daniel y Apocalipsis son dos libros bíblicos peculiares pues su mensaje eminentemente simbólico, con bestias que salen de la tierra y del mar y enfocado en el fin del mundo, causa temor entre los lectores de hoy. Sin embargo, ¿deberíamos temer a los eventos finales y al fin del mundo, tal como está registrado en estos dos libros proféticos? ¿Será posible encontrar en ellos un mensaje de esperanza? Para responder a estas preguntas, primero veremos cómo Daniel y Apocalipsis moldean 1) nuestra percepción de la historia, 2) nuestro concepto de la existencia y 3) nuestra expectativa del futuro en tres dimensiones: global, eclesiástico y personal.
Kompleksitas Argumentasi Berbasis Isu Sosiosaintifik pada Jenjang SD, SMP, dan SMA
Authors: Amalia Nur Fildzah , Riandi Riandi , Widodo Ari , Rochintaniawati Diana
Published: July 2019

The Student’s argument can be raised and developed using socioscientific issues. Socio-scientific issues about health is one of the social problems that the subject of public debate. This study aims to describe the complexity of the arguments in elementary school, middle school, and high school. The three level of education is a school which is shaded by one of the Foundation in Bandung. Participants involved in the study consisted of 31 elementary students, 14 middle school students, and 23 high school students. Data taken using a quisioner consist of five items concerning socioscientific issues as well as individual interviews based on the answers to the test written description. Data identified using Toulmin Argumentation Adaptation Pattern (TAP), which consists of four levels, namely, level 1 (claim), level 2 (claims, data and / or warrants), level 3 (claims, data / warrant, backing), and level 4 (claims, data / warrant, backing, qualifier). The results showed that the development of increasingly rising complexity of arguments according to their level. The complexity of the arguments on elementary students reached level 2-3, middle school and high school reached level 3. Percentage of level 3 more ascending towards the middle school to high school. Meanwhile, if viewed from the dominates of the arguments category level, level 2 emerged as the dominant category in elementary school, middle school, and high school.
Penerapan Self Generated Analogy sebagai Upaya Meningkatkan Kemampuan Berpikir Kreatif Siswa SMA pada Materi Sistem Peredaran Darah
Authors: Islamiati Fiqa , Kusnadi Kusnadi , Suhara Suhara
Published: July 2019

The aim of the reseatch want to analyze the improvement of students’ creative thinking ability in blood circulation system by applying self generated analogy. This research was done in a Public High School in Cimahi and was applied to two classes, the experiment class with 36 students and control class with 31 students.The method used for this research was quasi experimental. The samplewas selected by purposive technique. The data werecollectedby doing creative thinking ability test in form of essay, students’ questionnaire, and classroom observation. The difference of  creative thinking ability was reviewed form the result of the test given before and after treatment, and the improvement was seen using N-gain. The test result was compared by doing a statistical test using a software program, SPSS statistic 16.The result of the research shows that there is a significant difference in the creative thinking ability between the treatment and control group class, with a high improvement in the treatment class and medium improvement in control class. The average of posttest in the self generated analogy class is 83,2higher than the control class, which is 65,9. The N-gain result of creative thinking ability in the treatment class is around 0,59 (high category) whereas the control class is around 0,28 (low category). It shows that self generated analogy improves students’ creative thinking ability. The questionnaire showpositive response from students  that self generated analogy is able to improve students creative thinking abilityin teaching circulation system.
Penerapan Project Based Learning untuk Melatih Kemampuan Literasi Tumbuhan Abad 21 pada Siswa SMA
Authors: Rizkamariana Febby , Diana Sariwulan , Wulan Ana Ratna
Published: July 2019

This study aims to analyze the implementation of project based learning (PjBL) in improving high school students’ ability of 21st century botanical literacy. This study used quasi experimental method through non-equivalent control grup design. In the design of this study, there was a pre-test about botanical literacy before the treatment in experiment class and control, then it was done a treatment in experiment class with PjBL model and traditional learning in control class. After that, the students were given post-test about botanical literacy after learning activities. Sample in this study as much as 2 classes that belongs to class ten in one of High School in Cimahi City. The determination of study sample was conducted with purposive sampling technique because in choosing sample considering the condition of the students who have not learned yet about plants classification in school. Botanical literacy that was measured in this research is the ability to think critically to classify plants and solve the problem about plants. The result of the research is average of  N-gain in the experimental class  increased with moderate category, in the average of N-gain in the control class increased in low category. Overall, the activities in the stage of PjBL model has finished well by the teacher and students. Almost all the students agree that PjBL model give chances to the students to apply the knowledge on classifying plants, train on solving problem, and improve the learning motivation.
Perancangan Lembar Kerja Siswa pada Modul Pembelajaran Mandiri IPA Biologi SMP Berbasis Edmodo untuk Siswa Terdampak Bencana
Authors: Rahmayunita Desy , Sudargo Fransiska , Syulasmi Ammi
Published: July 2019

Natural disaster such as flood often hit Baleendah, district of Bandung. Flood impacts in environment damage and also in education. Students cannot go to school because of the access of the road, school and house blocked by flood. Therefore, alternative learning is needed through the use of teaching materials in the form of student worksheet based on Edmodo in providing services for students impacted by disaster. This study aims to produce Biology student worksheet in Junior High School self-directed learning products for students affected by disaster Edmodo-based. The research method used descriptive research using 4D development model (Define, Design, Develop and Disseminate). However, researcher only focus on the design stage.The respondents of this research are the students of grade VII and science teacher of SMPN 1 Baleendah. The instruments used include the assessment sheet of student worksheet development and student response questionnaire. Assessment is based on aspects of eligibility, readability and student responsiveness. The results showed that student worksheet developed based on the feasibility aspect previously considered by experts based on didactic requirements, construction requirements and technical requirements are categorized very well with the average percentage of 81.24%. Student response to student worksheet is very good, where student worksheet can help students in self-study. However, the independence of student learning is considered less, and still require direct assistance from the teacher. In addition, the availability of smartphones, signals, and quotas need to be considered in accessing this Edmodo-based student worksheet.
Classification of the post radiation fistulas of pelvic organs
Authors: Vasiliev L. A. , Kostyuk I. P. , Ivanov S. A. , Kaprin A. D.
Published: July 2019

Background. In recent years, we observe technological and scientific growth in the field of medicine. It makes revise of existing ideas about certain pathological conditions. Such a serious complication of radiation treatment as fistulas of the pelvic organs is not excluded. All available classification of the post radiation fistulas of pelvic organs or consider them in the total mass of fistulas, specifying only the cause of occurrence, or even fall into the category of “others”. Moreover, the existing classifications do not reflect the medical tactics needed in each particular case.

The study objective is to develop classification of radiation-induced fistulas of the lower pelvis which would assist with selection of the optimal treatment tactics.

Materials and methods. This study analyzed the results of the examination and treatment of 82 cases of post-radiation pelvic fistula.

Results and conclusion. Treatment of patients according to the proposed classification allowed to attain stable recovery in 92 % of cases.
Capabilities of preoperative targeted therapy in treatment of bone metastases in renal cancer
Authors: Yurmazov Z. A. , Lushnikova N. A. , Spirina L. V. , Usynin E. A. , Slonimskaya E. M. , Anisenya I. I. , Bogoutdinova A. V.
Published: July 2019

The study objective is to evaluate the effectiveness of preoperative targeted therapy, spectrum and rate of adverse events, as well as quality of life in patients with bone metastases of renal cell carcinoma.

Materials and methods. The study was conducted at the Research Institute of Oncology, Tomsk Medical Research Center between 2014 and 2018. The study included 34 patients with bone metastases of renal cell carcinoma who received preoperative targeted therapy with pazopanib for 8 weeks. All patients underwent surgical treatment of both the primary tumor and bone metastases.

Results and conclusion. It was shown that preoperative targeted therapy is characterized by a high rate of clinical response and satisfactory tolerability. In some cases, preoperative targeted therapy improves the conditions for surgical treatment of metastatic bone lesions, decreases intraoperative blood loss, decreases the volume and duration of surgical intervention, which, in turn, allows to preserve bigger range of motion in the affected bone segment and improve patients’ quality of life.
Global‐ and Local‐Scale High‐Resolution Event Catalogs for Algorithm Testing
Authors: Linville Lisa , Brogan Ronald Chip , Young Christopher , Aur Katherine Anderson
Published: July 2019

During the development of new seismic data processing methods, the verification of potential events and associated signals can present a nontrivial obstacle to the assessment of algorithm performance, especially as detection thresholds are lowered, resulting in the inclusion of significantly more anthropogenic signals. Here, we present two 14 day seismic event catalogs, a local‐scale catalog developed using data from the University of Utah Seismograph Stations network, and a global‐scale catalog developed using data from the International Monitoring System. Each catalog was built manually to comprehensively identify events from all sources that were locatable using phase arrival timing and directional information from seismic network stations, resulting in significant increases compared to existing catalogs. The new catalogs additionally contain challenging event sequences (prolific aftershocks and small events at the detection and location threshold) and novel event types and sources (e.g., infrasound only events and long‐wall mining events) that make them useful for algorithm testing and development, as well as valuable for the unique tectonic and anthropogenic event sequences they contain.
Los verbos recíprocos en los diccionarios
Authors: Vázquez Glòria , Fernández-Montraveta Ana
Published: July 2019

En este artículo se presenta un análisis lexicográfico de un subgrupo de la clase de los verbos recíprocos léxicos del español, que en general ha sido muy poco estudiada. Concretamente hemos estudiado 49 verbos polisémicos que presentan al menos una acepción recíproca y pronominal. En primer lugar, se constata si, tal como propone Dimitriadis (2008), cuando estos verbos adoptan el clítico, la presencia de este elemento sirve para contrastar el sentido recíproco con otros sentidos. En segundo lugar, se analiza el tratamiento que han recibido estos predicados en tres obras lexicográficas con el fin de verificar en qué porcentaje estos recursos identifican el uso simétrico de estos verbos polisémicos, teniendo en cuenta especialmente que algunos usos no recíprocos de estos predicados son muy próximos a los recíprocos. En tercer lugar, dado que en el análisis realizado se han observado ciertas ambivalencias en la representación lexicográfica de este tipo de predicados, el objetivo último es presentar una propuesta de representación lexicográfica para los usos recíprocos de estos verbos teniendo en cuenta la distinta casuística observada.
Natureza, aprendizaxe experiencial e actividades cooperativas na educación primaria
Authors: Cutrín Santos Raquel , Basanta Camino Silvia , Navarro Patón Rubén
Published: July 2019

Neste estudo faise unha revisión de tres correntes actuais que poden transformar a forma de traballar nos centros de educación primaria. Correntes metodolóxicas que se afastan das convencionais, pero que en absoluto son de recente creación, senón que xa levan varias décadas sendo estudadas tal e como se plasma na literatura. Afondaremos, así, nas actividades na natureza, na aprendizaxe experiencial e no traballo cooperativo, desde unha perspectiva teórica. Do mesmo xeito, analizaremos o currículo da educación primaria co fin de ver se teñen cabida nos programas educativos actuais.
A filosofia do Bem Viver, inspiradora para uma educação na natureza
Authors: Pinheiro Inez , Fernández Herrero Beatriz
Published: July 2019

O presente trabalho propõe uma análise da filosofia do Bem Viver como uma alternativa ao paradigma da vida contemporânea, que passa por um distanciamento do ser humano em relação à natureza, centrado no uso abusivo da mesma. Não é apenas uma crítica ao sistema capitalista e ao modelo ocidental, que se pretendem universais, mas também uma reflexão sobre as possibilidades que diferentes modos de vida já existentes podem oferecer, como os dos povos indígenas, que inspiram o Bem Viver e nos convidam a pensar em novos modelos de vida e relações, mais orientados para o respeito, a justiça, a solidaridade e a paz. A possibilidade do Bem Viver só pode ser conquistada através de um novo modelo de educação, que deve abandonar sua doutrina unificadora para se tornar crítica e libertadora. Para justificar essa proposta, uma análise do projeto educacional «Escolas de Bem Viver» do Equador é apresentada para mostrar que o Bem Viver não é algo irrealizável, mas sim possível.
María Victoria Moreno ou a deconstrución da masculinidade hexemónica desde as marxes
Authors: Carballal Miñán Patricia
Published: July 2019

A partir da década de 1970 do século pasado o discurso feminista fíxose explícito en certa literatura infantil e xuvenil como reacción aos estereotipos sexistas presentes nas obras para os/ as máis novos/as. Deste xeito agromaron protagonistas femininas ousadas e activas, á vez que medraban as historias protagonizadas por personaxes de nenas e mozas, que foron atentamente examinadas pola crítica. As personaxes masculinas tamén mudaron as súas características e algunhas delas foron construídas con trazos diferenciados da masculinidade hexemónica, ben para buscar a identificación co seu lectorado máis novo, ben para abrirlle novas identidades; porén, apenas foron analizadas cualitativamente. Neste estudo examinaremos os atributos principais de Antón Andrade e Nicolau Arís, os protagonistas das dúas primeiras obras de María Victoria Moreno dirixidas a público xuvenil á luz dos estudos sobre a masculinidade que naceron tamén á calor das ideas feministas.
Encarnación Martínez Alfaro; Leoncio López-Acón Cabrera; Gabriela Ossenbach Sauter (eds.): Ciencia e innovación en las aulas. Centenario del Instituto-Escuela (1918-1939)
Authors: Costa Rico Antón
Published: July 2019

Recensión de libro: Encarnación Martínez Alfaro; Leoncio López-Acón Cabrera; Gabriela Ossenbach Sauter (eds.) (2018). Ciencia e innovación en las aulas. Centenario del Instituto-Escuela (1918-1939).
M. Banguesas Vázquez; J. Aguilar Madrazo; R. Iglesias Veiga: IES Pino Manso do Porriño. 1966-2016. 50 anos de ilusións
Authors: Malheiro Gutierrez Xosé Manuel
Published: July 2019

Recensión de libro: M. Banguesas Vázquez; J. Aguilar Madrazo; R. Iglesias Veiga (2018). IES Pino Manso do Porriño. 1966-2016. 50 anos de ilusións.
Revisión del proceso de separación de fases del gas natural a alta presión en la industria Oil&Gas
Authors: Prieto Jiménez Natalia , González Silva Germán , Chaves Guerrero Arlex
Published: July 2019

La separación física de líquidos y gases es una de las operaciones de producción, procesamiento y tratamiento en la industria petrolera, necesaria para prevenir daños en equipos rotativos, evitar corrosión en tuberías y cumplir con las especificaciones de calidad del gas natural para uso doméstico.  Cuando la presión de operación aumenta, la diferencia de densidades entre las fases disminuye, lo cual dificulta el proceso de separación. Se realiza la revisión del estado del arte, desde los años 90 hasta el presente, de las diferentes metodologías para separar las fases líquida y gaseosa del gas natural, así como las variables de diseño con aplicación a sistemas que operan a alta presión; prestando especial énfasis en los avances encontrados utilizando Dinámica de Fluidos Computacional. Los resultados muestran que, aunque  los separadores centrífugos y los separadores supersónicos son más compactos y de fácil mantenimiento comparados con los separadores gravitacionales, éstos últimos continúan siendo la estrategia más favorable cuando se combinan alta presión y baja cantidad de líquido (menos del 4% vol), como es el caso del gas natural. Conclusión adjudicada, en parte, a la falta de estudios experimentales/numéricos que involucren al gas natural en equipos alternativos al separador gravitacional
Прекариат: возможна ли успешность на рынке труда (на примере фрилансеров)
Authors: Голованова Дарья Владимировна , Дудина Ольга Мухаметшевна
Published: July 2019

Актуальность исследования обусловлена распространением на рынке труда различных групп работников, которых объединяют в «прекариат», то есть слой с «крайне нестабильной занятостью». Каков его состав, какие последствия он несет для работников и для общества? В статье рассматривается лишь одна из групп прекариата, а именно - фрилансеры. По многим критериям она является достаточно успешной группой на рынке труда, удовлетворены ее многие социальные потребности, хотя и она уязвима в плане отсутствия социального пакета, мошенничества работодателя и т.д. В статье сравниваются две группы: фрилансеры и нефрилансеры, которые «примеряют» на себя этот формат занятости. На основе инициативного социологического исследования авторы делают вывод о том, что успешность данной группы, относимой к прекариям, обусловлена высоким уровнем образования, профессионализма, организованностью, умением работать в одиночестве. Нефрилансеры в меньшей степени обладают этими качествами, поэтому среди них менее половины стремится заняться фрилансом.
В любом случае любые группы, входящие в прекариат, нуждаются в изучении и организации институциональной взаимопомощи (в профессиональных организациях и сообществах), а также помощи государства в плане регулирования трудовых отношений и контроля за выполнением обязательств работодателями
Стажировки как инструмент формирования профессиональных компетенций выпускников и обеспечения их занятости
Authors: Никулина Юлия Николаевна
Published: July 2019

В статье рассмотрены основные элементы процесса организации стажировки как инструмента обеспечения занятости молодежи в современных условиях. Автором систематизированы основные проблемы организации практико-ориентированного образования студентов в части организации и проведения практики, которые подтверждаются результатами исследования уровня профессиональной подготовленности с позиции выпускников. Автором разработан механизм реализации регионального проекта «Практика-стажировка-занятость», включающий студенческие работы и стажировки в качестве социального лифта для молодежи региона. Внедрение данного проекта позволит комплексно подойти к проблеме практического обучения студентов в рамках формирования профессиональных компетенций и развивать новые формы взаимодействия с предприятиями-работодателями в целях подготовки конкурентоспособных специалистов для экономики региона
Transfer of Regional Government Stock in PT. Indotan Lombok Barat Bankit through Sircular Shareholder General Meeting
Authors: Fikry Lalu Athfal , Hs Salim , Kurniawan Kurniawan
Published: July 2019

This study aims to analyze the transition of shares of Regional Government through Circular shareholders general meetings. Related to this matter, the regulation of share transfer through the Circular general shareholders meeting. This research is a type of normative research, with the approach used is a legal approach and a conceptual approach. Circular transfer of shares is clearly stipulated in article 91 of Law Number 40 of 2007 concerning Limited Liability Companies. That a decision outside the general meeting of shareholders approved by all shareholders is a "binding" decision. That is, the decision has the same legal force as the decisions of the general meeting of shareholders carried out physically and conventionally. Then the next arrangement is regulated in article 14 of the Cooperation Agreement between Indotan Lombok, Pte. Ltd., PT Puri Permata Mega, and West Lombok Regency Government Based on Notarial deed Number AHU-AH.O1.10-09847. If in the analysis of the agreement theory, this agreement has fulfilled the legal requirements of an agreement. The implementation was carried out with evidence that PT Puri Permata Mega had transferred its shares to PT Indotan Lombok, Pte. Ltd. This is evidenced by the agreement of Indotan Lombok, Pte, Ltd and the West Lombok Regency Government.
Molecular identification and genetic variation of Alternaria species isolated from tomatoes using ITS1 sequencing and inter simple sequence repeat methods
Authors: Mohammadi Abdelnasser , Bahramikia Seifollah
Published: July 2019

Background and Purpose: Alternaria is one of the most abundant fungi that exists in numerous places around the world. This saprophytic fungus causes diseases in plants and accounts for the spoilage of cereals in warehouses. The aim of this study was to identify Alternaria isolates based on their morphological characteristics and internal transcribed spacer ribosomal RNA (ITS rRNA) sequencing method. To this end, genetic diversity in the isolates was also examined using inter simple sequence repeat (ISSR) markers. Materials and Methods: To conduct this research, a total of 60 tomato samples with black spots were collected from supermarkets in Khorramabad City, Iran, in the winter of 2017. The specimens were cultured on a potato dextrose agar medium. After the purification of the fungus by the single-spore method, the identification of the species was carried out using morphological characteristics and ITS rRNA sequencing by polymerase chain reaction. The genetic diversity of the identified species with four primers was evaluated using the ISSR marker. Results: Based on the sequencing of the ITS1 region, all the isolates were identified as A. alternata. Cluster diagrams for the ISSR marker were classified into six distinct groups. The mean polymorphism information content was obtained as 0.35, indicating the effectiveness of the primers in the separation of the isolates. Conclusion: The sequencing of ITS1 led to the identification of Alternaria species that are morphologically similar. The production of various mycotoxins by A . Alternata species leads to the contamination of livestock and human food. Regarding this, the investigation of the genetic diversity of A. alternata species using the ISSR marker would facilitate the identification of suitable and effective strategies for controlling the fungal and mycotoxin contamination of human nutrition.
Exposición al crimen violento y cambios en los arreglos residenciales de niñas y niños en México
Authors: Ramirez David , Perez-Amador Julieta
Published: July 2019

Los efectos del homicidio en la esperanza de vida están bien documentados en la literatura; sin embargo, ha sido poca la atención sobre el impacto de la tasa de homicidio en las dinámicas familiares y en la estructura familiar. Para ayudar a cubrir este vacío en la literatura, vinculamos datos censales de 1990, 2000 y 2010 con tasas de homicidio a nivel municipal para investigar la relación entre el incremento en la tasa de homicidio y el cambio en los arreglos residenciales. Por medio de técnicas de modelación aptas para inferir su asociación, buscamos identificar el posible impacto de diferentes niveles en la tasa de homicidio en los arreglos residenciales de niñas y niños a nivel local. Nuestros resultados aportan evidencia sobre los efectos del crimen violento en el bienestar de las familias y de las niñas y niños en el país.
THE CONCEPT OF SHAKESPEARE’S PERSONALITY AND CREATIVITY IN THE LITERARY-CRITICAL WORKS OF I.A. AKSENOV
Authors: Zhatkin Dmitry N. , Futljaev Nikita S.
Published: July 2019

Purpose: The article analyzes the literature-critical publications of Aksenov of the late 1920s and the first half of the 1930s with the aim of examining the personality and creativity of Shakespeare via socio-cultural, comparative-historical, historical-genetic, socio-cultural and biographical methods.

Methodology: In accordance with the subject of study, comparative-historical, cultural-historical and historical-typological methods, methods of problem and comparative analysis were used.

Main Findings: As a result, Aksenov systematically destroyed the widespread misconception of the epoch that Shakespeare was almost the only pillar of Elizabethan drama. In conclusion, Aksenov considered literary flair a special merit of Shakespeare, with which he was editing the material, without hiding the merits of his predecessors and without correcting or giving realistic contours to mysterious characters.

Applications: This research can be used by literary students, from universities and other literary centers.

Novelty/Originality: In this research, Shakespeare’s personality and creativity were studied from his literary-critical works.
Synthesis, Characterization, and Molecular Docking Studies of Fluoro and Chlorophenylhydrazine Schiff Bases
Authors: ŞENOCAK Ayşegül
Published: July 2019

Six Schiff bases synthesized by
condensation reaction of p-fluoro and chlorophenylhydrazines with some carbonyl
compounds were reported in this work. Structures of the prepared compounds were
elucidated by FT-IR, 1H- and 13C-NMR spectroscopy. FT-IR
spectra exhibited characteristic transitions for all compounds. Also, their
structures were proved by NMR spectroscopy, especially with the imine peak
which is an indicator of the formation of Schiff bases. In addition, molecular
docking studies of the Schiff bases were carried out on Alzheimer’s disease. The
calculated docking scores and inhibition constants pointed out the usage
probability of 2-chloro-5-nitrobenzaldehyde Schiff bases as a new drug
candidate for Alzheimer’s disease after structural regulations.
Desafíos actuales de la enseñanza de la filosofía
Authors: Díaz Bernal Juan Guillermo , Pulido Cortés Óscar
Published: July 2019

La enseñanza de la filosofía se ha venido constituyendo como un campo teórico y metodológico en el último tiempo. Las continuas amenazas que sobre este saber milenario que se han hecho desde diversas acciones políticas han concitado una especial defensa del saber y de su posibilidad de ser enseñada en escuelas y universidades. Esta defensa se manifiesta no solo en las luchas políticas y normativas en diversos países, sino también en la creación de asignaturas, programas, proyectos de investigación, redes de maestros y conceptos. El informe de la UNESCO la filosofía como escuela de libertad (UNESCO, 2011)publicado en francés en el año 2007 produjo un completo estado de la cuestión sobre enseñanza de la filosofía a nivel mundial, hoy 12 anos después la situación sigue consolidándose como preocupación y a la vez con esperanza entre las restricciones de gobierno neoliberales y conservadores que ubican a la filosofía como algo inútil y peligroso en la formación de las nuevas generaciones y las nuevas formas y manifestaciones de prácticas filosóficas contemporáneas. Diversos estudios han demostrado como la reflexión sobre enseñanza de la filosofía en Colombia ha venido ganado espacio en publicaciones especializadas en filosofía  (Díaz & Espinel, 2019; Pulido, Espinel, & Gómez, 2018), educación e incluso se han dedicado números monográficos para abordar la problemática. Esta sensación ha sido reconocida por la revista Cuestiones de filosofía que dedica este fascículo a contribuir con la discusión latinoamericana al respecto.
Students’ Perception of Lecturers’ Utilization of Information and Communication Technology (ICT) Tools for Instructional Delivery in Science Education Programme
Authors: Akpan Iniobong Fred , Itighise Atim Edet
Published: July 2019

The study was to investigate students’ perception of lecturers in utilizing Information and Communication Technology (ICT) tools in instructional delivery in science education programme in Akwa Ibom State University. The researchers adopted descriptive survey design for the study. The population of the study which also formed the sample for the study were one hundred and thirty eight year three students of the Science Education Department, Akwa Ibom State University, Ikot Akpaden, Mkpat Enin L. G. A. Two research questions were formulated to guide the study. A questionnaire titled “Students’ Perception of Lecturers Utilization of Information and Communication Technology Tools Questionnaire (SPLUICTTQ) was used for data collection. The researchers personally administered the questionnaire to the students (respondents) and retrieved immediately after completion. The data was analysed using percentages. The results indicated that students’ perception of lecturers’ use of email and computer in instructional delivery is 36.23% and 34.78% higher than all other ICT tools. The result also revealed excellent utilization of internet and email for instructional delivery as shown in the table with 53.52% and 60.80% respectively, while audio tapes and computer were averagely used with 44.20% and 42.28% respectively as ICT tools in instructional delivery. The result showed that 44.26% was the perceived percentage of lecturers not using teleconferencing at all. It was concluded that the recommendations of school net (2006) and that of National Policy on Education on the use of ICT tools in instructional delivery be re-emphasized to encourage lecturers in the Department of Science Education on the use of ICT tools for effective instructional delivery process.
Nilai Total Ketidakteraturan-H pada Graf Cn x P3
Authors: Aritonang Winda , Hinding Nurdin , Amir Amir Kamal
Published: July 2019

AbstrakPenentuan nilai total ketidakteraturan dari semua graf belum dapat dilakukan secara lengkap. Penelitian ini bertujuan untuk menentukan nilai total ketidakteraturan-H pada graf Cn x P3 untuk n ≥ 3 yang isomorfik dengan . Penentuan nilai total ketidakteraturan-H pada graf Cn x P3 dengan menentukan batas bawah terbesar dan batas atas terkecil. Batas bawah dianalisis berdasarkan sifat-sifat graf dan teorema pendukung lainnya. Sedangkan batas atas dianalisa dengan pemberian label pada titik dan sisi pada graf Cn x P3.Berdasarkan hasil penelitian ini diperoleh nilai total ketidakteraturan-H pada graf ths(Cn x P3, C4)=.Kata kunci : Selimut-H, Nilai total ketidakteraturan-HAbstractThe determine of H-irregularity total strength in all graphs was not complete on graph classes. The research aims to determine alghorithm the H-irregularity total strength of graph Cn x P3 for n ≥ 3 with use H-covering, where H is isomorphic to C4. The determine of H-irregularity total strength of graph Cn x P3 was conducted by determining lower bound and smallest upper bound. The lower bound was analyzed based on graph characteristics and other supporting theorem, while the upper bound was analyzed by edge labeling and vertex labeling of graph Cn x P3.The result show that  the H-irregularity total strength of graph ths(Cn x P3, C4)=.Keyword : H-covering, H-irregularity total strength
ANALISIS KESTABILAN DAN KONTROL OPTIMAL MODEL LESLIE-GOWER FUNGSI RESPON HOLLING III DENGAN PEMANENAN PADA POPULASI PREDATOR DAN PREY
Authors: Febriyanti Himmatul Ulya , Toaha Syamsuddin , Kasbawati Kasbawati
Published: July 2019

This article modified the leslie-gower model on harvesting with predator and prey population. This study aims at construct a modification of leslie-gower model with holing III response function. In addition, there is an effort harvesting in predator and prey population, analyzing an equilibrium point, finding bionomic equilibrium and the condition where the present value is maximum from net income by controlling harvesting in both populations. In the modified leslie-gower model there is an equilibrium point  which is asymptotically stable and when there have harvesting, the equilibrium point  is also asymptotically stable. Bionomic equilibrium from harvesting on the modified leslie-gower model is maximizing the profit function π of harvesting on a model with the maximum pontryagin principle resulting an optimal equilibrium) affected by instantaneous rate of discount δ.
Enhancing Critical Thinking Skills of Students Related to Temperature and Heat Topics Through Problem Solving- Laboratory Model
Authors: Malik Adam , Novita Yeni , Nuryantini Ade Yeti
Published: July 2019

This study aims to determine the implementation of the learning problem-solving laboratory model and improvement of critical thinking skills of students on temperature and heat topic. The method used in this research was pre-experiment, with one-group pretest-posttest design. The population of this study was class X SMA Muhammadiyah 1 Garut. The sample was selected by random sampling technique, with a sample of one class X-2, amounting to 30 people. The implementation of problem-solving laboratory model learning was observed by observers with observation sheets and improvement of students' critical thinking skills measured by essay tests. The results showed that the average implementation of problem-solving laboratory model learning for teacher activities was 84% and student activities at 80% were both categorized well. There was an increase in the critical thinking skills of students shown by the average of the normalized gain value of 0.64 include the medium category. Thus, the problem-solving laboratory model learning can be used as an alternative in improving students' critical thinking skills on the topic of temperature and heat.
PENINGKATAN KETERAMPILAN BERKOMUNIKASI MELALUI MODEL PEMBELAJARAN KOOPERATIF JIGSAW
Authors: Rizki Sofiyana
Published: July 2019

Abstract

This research was aimed to overcome the low of students’ communication skills in the learning process which applied Jigsaw cooperative learning model in the class five of Tingkir Lor 02 Elementary School Tingkir sub-district Salatiga city. This classroom action research used spiral model which referred to Kemis and Mc. Tagart’ research design. This research procedure was done by implementing Jigsaw cooperative learning model which was planned by started from design arrangement, action, observation, and reflection which is then followed by the next spiral cycle. This classroom action research applied two cycles pattern. The conclusion of this research is the implementation of Jigsaw cooperative learning can improve students’ communication skills. It can be seen from the increase of communication skills average score percentage from cycle I and cycle II that is 11,78% with average score in cycle I is 75,5 increased into cycle II that is 84,4.

Keywords: Communication Skills,  Jigsaw Model

 

Abstrak

Penelitian ini bertujuan untuk mengatasi rendahnya keterampilan berkomunikasi peserta didik dalam pembelajaran dengan menerapkan model pembelajaran kooperatif  Jigsaw di kelas V di SD Negeri Tingkir Lor 02 Kecamatan Tingkir Kota Salatiga. Penelitian tindakan kelas ini menggunakan model spiral yang mengacu desain penelitian Kemmis dan Mc. Taggart. Prosedur penelitian ini dilaksankan dengan melaksanakan pembelajaran menerapkan model pembelajaran kooperatif Jigsaw yang dierencanakan dengan dimulai dari penyususnan rancangan, pelaksanaan tindakan, pengamatan (observasi), dan refleksi yang kemudian diikuti dengan siklus spiral berikutnya. Penelitian tindakan  kelas ini menerapkan pola dua siklus. Kesimpulan penelitian ini yaitu penerapan model pembelajaran Kooperatif Jigsaw dapat meningkatkan keterampilan berkomunikasi peserta didik. Hal tersebut dapat dilihat dari kenaikan presentase skor rata-rata untuk ketererampilan berkomunikasi dari siklus I ke siklus II yaitu sebesar 11,78%, dengan skor rata-rata pada siklus I yaitu 75,5 naik di siklus II  menjadi 84,4.

Kata Kunci: Keterampilan Berkomunikasi,  Model  Jigsaw