bluuebunny/crossref_metadata_2025 huggingface dataset:
GraphRXN: A Novel Representation for Reaction Prediction
Authors: Li Baiqing , Su Shimin , Zhu Chan , Lin Jie , Hu Xinyue , Su Lebin , Yu Zhunzhun , Liao Kuangbiao , Chen Hongming
Published: May 2022

In recent years, it has been seen that artificial intelligence (AI) starts to bring revolutionary changes to chemical synthesis. However, the lack of suitable ways of representing chemical reactions and the scarceness of reaction data has limited the wider application of AI to reaction prediction. Here, we introduce a novel reaction representation, GraphRXN, for reaction prediction. It utilizes a universal graph-based neural network framework to encode chemical reactions by directly taking two-dimension reaction structures as inputs. The GraphRXN model was evaluated by three publically available chemical reaction datasets and gave on-par or superior results compared with other baseline models. To further evaluate the effectiveness of GraphRXN, wet-lab experiments were carried out for the purpose of generating reaction data. GraphRXN model was then built on high-throughput experimentation data and a decent accuracy (R2 of 0.713) was obtained on our in-house data validation. This highlights that the GraphRXN model can be deployed in an integrated workflow which combines robotics and AI technologies for forward reaction prediction.
Effect of Inflammatory Markers on the Pathologic Complete Response in the Neoadjuvan Treatment of Her-2 Positive Local Advanced Breast Cancer
Authors: Gulmez Ahmet , Harputluoglu Hakan
Published: May 2022

There are various effective combinations of therapy in the neoadjuvant treatment of human epidermal growth factor receptor 2 (Her-2) positive breast cancer (BC). One of the best-known of these treatments is the dual blockade with pertuzumab and trastuzumab, which is an anti-Her-2 treatment added to chemotherapy. The aim of this study was to retrospectively investigate the rate of pathological complete response (pCR) and markers predicting this response for trastuzumab and pertuzumab-containing regimens compared to trastuzumab-containing regimens for stage II to III HER-2 positive BC. In this study, we retrospectively analyzed the data of patients with Her-2 positive advanced BC who were treated with trastuzumab or trastuzumab and pertuzumab in addition to neoadjuvant chemotherapy. Patients were classified according to their pre-treatment clinical stages, hormone receptor status, Her-2 immuno-histochemical score, ki-67 index, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and prognostic nutritional index (PNI) ratio. The cut-off values of these parameters were calculated by performing a Roc-Curve analysis. Patients with and without pCR with neoadjuvant therapy were evaluated. For NLR, it was 1.9 ± 0.85 in patients with pCR and 2.4 ± 0.83 in patients without pCR. For PLR it was 112 ± 53.3 and 129.4 ± 36.2, respectively. For PNI, it was 51.6 ± 5.8 and 48.1 ± 5.9. Low NLR and PLR as well as high PNI were significantly associated with pCR. In addition, the pCR of patients with Hormone Receptor negativity and dual Her-2 blockade was statistically significant. This is the first study in the literature to show that prognostic scores such as NLR, PLR, and PNI have statistically significant benefits on pCR in patients treated with the neoadjuvant dual bloc
Assessment of macroalgal biomass potential in Tunisia for bioethanol production
Authors: Smichi Neila , Messaoudi Yosra , Moujahed Nizar , Messaoud Chokri , Langar Habib , Bezzarga Mounir , Gargouri Mohamed
Published: May 2022

The valorization of marine macroalgal biomass is among the most promising international programs focusing on the sustainable exploitation of marine environment. However, macro-algal biomass remains unexploited in Tunisia even though it represents a renewable and highly abundant biomass. This causes several environmental disorders due to the excessive proliferation of several algal species. The objective of this work is to study the potential use of macroalgae as biofuels feedstock in the Mediterranean region and particularly in Tunisia. This study focuses on certain macroalgal species collected from Bizerte and Tunis lagoons. It reports the biochemical characterization of the studied macroalgae in order to determine their possible valorization areas and demonstrate their richness in high value molecules. In fact, our experiments show that the maximum protein content of 16.22%±0.270 was obtained with G. verrucosa and the maximum carbohydrates content of 58.46%±1.52 was obtained with Dictyopteris polypodoies. This leads us to believe that macroalgae constitute a potential source of fiber and proteins. After a sulfuric acid pretreatment, the macroalgae’s solid fractions were hydrolyzed using cellic Ctec2 enzymatic extract leading to a maximum reducing sugars yield of 324.6 mg/gDM. Monomeric sugars from the studied macroalgae hydrolyzates were fermented, leading to maximum ethanol yield of 0.24g/gDM.
Extraction and generalisation of category-level information during visual statistical learning in autistic people
Authors: Parsons Owen , Baron-Cohen Simon
Published: May 2022

Background We aimed to assess whether autistic individuals were able to generalise across contexts when building statistical expectations of their environment to the same extent as non-autistic individuals. We did this by assessing the implicit awareness of statistical regularities in a sequence of naturalistic scene images in both autistic and non-autistic individuals. Methods125 participants (61 participants with an autism diagnosis and 64 non-autistic controls) were presented with a fast serial presentation sequence of images and given a cover task to avoid attention being explicitly drawn to patterns in the underlying sequences. This was followed by a two-alternative forced choice task to assess participants’ implicit recall. Participants were presented with 1 of 3 unique versions of the task, in which the presentation and assessment of statistical regularities was done at either a low feature-based level or a high semantic-based level. ResultsThere were no significant group differences in how performance varied across the 3 conditions, but there was an overall significant reduction in visual statistical learning in the autistic group. There was also a lack of statistical significant effect of learning for the autistic participants who completed the generalisation condition.LimitationsWhile the overall sample was fairly large, the sample sizes for the subgroups within the study were modest, so the lack of statistically significant effect of learning for the autistic participants who completed the generalisation condition may be due to a lack of power rather than an true absence of learning. Additionally, this study did not directly assess if semantic information was being processed to a similar extent by both autistic and non-autistic participants.ConclusionsThese results do not support the claim that autistic individuals experience difficulties in either acquiring or generalising statistic regularities at the category-level, but suggest that differences in visual statistical learning occur in autistic people.
Users’ perceptions of how an unmoderated eating disorder community may benefit or harm their recovery
Authors: Jones Maegan E. , Salafia Elizabeth H. Blodgett , Leonard Kerrie C.
Published: May 2022

Background: While the negative and positive outcomes of pro-eating disorder groups have been well-documented, more research is needed on the effects of pro-recovery communities. In particular, a gap in knowledge remains surrounding users’ feelings about their experiences in such communities. Using open-ended questions, we interviewed those involved in the recovery community on the social media site Tumblr, to determine how the community helped/did not help with recovery, and how it made them feel about recovery. Methods: Participants (n = 29) answered a series of Likert and open-ended questions. The open-ended questions were examined using thematic analysis to learn about users’ lived experiences. Results: When asked if/how the community helped with recovery, positive themes of “not alone,” “motivation,” and “encouragement” were identified, as were negative themes of “competition” and “triggering content.” When asked if the community made them feel better or worse about their recovery, a theme of comparison was identified, with two subthemes: positive and negative. In addition, a theme of type of content was found. Conclusions: Participants believed the community was helpful and made them feel better about recovery, with some caveats. Recovery communities on unmoderated sites or social media applications may be useful tools during the recovery process.
Modelling the Latent cardio-metabolic profiles of individuals in an epidemiological investigation
Authors: Esmaeili Parya , Roshanravan Neda , Mousavi Saeid , Ghaffari Samad , Alamdari Naimeh Mesri , Asghari-Jafarabadi Mohamad
Published: May 2022

Introduction: This study aimed to explore the cardio-metabolic risk factors profile to assess the underlying predictors of these profiles in healthcare workers of the AZAR cohort population.Methods: This cross-sectional study was performed on 500 healthcare providers, official staff, and professors aged 18 to 75 years of Tabriz University of Medical Sciences. Latent profile analysis (LPA) was used to classify the subjects according systolic blood pressure, diastolic blood pressure, diabetes, smoking, hypertension, statin, metabolic syndrome, BMI, lipid profiles, hemoglobin and hematocrit. Logistic regression predicted the underlying predictors of latent profile. Results: The individuals were classified into two LPA-driven classes, including a low risk profile (n = 210), and a high-risk profile (n = 290). High-risk group were older, and was more likely to be male than those in the low-risk group (P<0.05). The prevalence of metabolic syndrome, diabetes, hypertension, systolic blood pressure, diastolic blood pressure, HDL-cholesterol, LDL-cholesterol, total cholesterol and hemoglobin was significantly higher in the high-risk group than the low-risk group (P<0.05). But statin was not significantly different between the two groups (P>0.05). Compared with the low risk profile; BMI (OR=3.30, 95% CI: 1.10–9.93), triglyceride (OR=1.02, 95% CI: 1.00–1.05), smoking (OR=0.05, 95% CI: 0.01–0.95) and hematocrit (OR=12.07, 95% CI: 3.46–42.11) were higher in the high-risk profile.Conclusion: Identifying risk factors may prevent the incidence of cardiometabolic disease. Higher BMI levels, higher triglyceride values, higher hematocrit, and lower HDL values are better predictors for identifying a cardio-metabolic high-risk profile.
Effects of Glutathione S-Transferases (GSTM1, GSTT1 and GSTP1) gene variants, alone and in combination with smoking or drinking, on cancers: a meta-analysis
Authors: Hu Qiurui , Huang Yonghui , Wei Zhenxia , Chen Li , Luo Ying , Li Xiaojie , Li Cuiping
Published: May 2022

This meta-analysis aimed to systematically describe the association between cancer risks and Glutathione S-Transferases (GSTs) among smokers and drinkers. Literatures were searched through PubMed, Web of science, CNKI and WANFANG published from 2001 to 2022. Stata was used with fixed-effect model or random-effect model to calculate pooled odds ratios (ORs) and the 95% confidence interval (95% CI). Sensitivity and heterogeneity calculations were performed, and Begg and Egger's test was used to look for publication bias. Regression analysis was performed on the correlated variables about heterogeneity, and the false-positive report probabilities (FPRP) and the Bayesian False Discovery Probability (BFDP) were calculated to measure the confidence of a statistically significant association. A total of 83 studies were eligible for GSTs and cancer with smoking status (19311 cases and 23194 controls), including 13 articles referred to drinking status (4308 cases and 5476 controls). GSTM1-null had significant associations with cancer risks, alone (OR = 1.362, 95%CI=(1.204–1.540) and in combination with smoking (OR = 1.305, 95%CI=(1.149–1.482); GSTT1-null had significant associations with cancer risks in combination with smoking (OR = 1.265, 95%CI = 1.032–1.552) or drinking (OR = 1.423, 95%CI = 1.042–1.942); and negative associations were found between GSTP1rs1695(AG + GG/AA) and cancer risks among Caucasians in combination with smoking (OR = 0.788, 95%CI = 0.653–0.950) or drinking (OR = 0.724, 95%CI = 0.571–0.919). Thus, the effect of GSTM1-null on cancer risks might not be augmented in combination with smoking; GSTT1-null might increase cancer susceptibility among smokers and drinkers; while a negative association between GSTP1rs1695 genetic variants and cancer risks could be seen in Caucasians.
Effects of high pressure treatments (ultra-high hydrostatic pressure and high pressure homogenization) on bighead carp (Aristichthys nobilis) myofibrillar protein native state and its hydrolysate
Authors: Chen Mengting , Wang Lan , Zheng Changliang , Wu Wenjin
Published: May 2022

The impacts of four treatments ultra-high hydrostatic pressure (UHP), high pressure homogenization (HPH), combined UHP + HPH (U-H), and HPH + UHP (H-U) on bighead carp (Aristichthys nobilis) myofibrillar protein (BMP) structure, functional hydrolysis property to pepsin, and antioxidant activity of hydrolysates were investigated. All treatments led to increase in low-molecular-weight BMP, the BMP stability, and hydrophobic group exposure, but decrease in total sulfhydryl content and BMP particle size, thus resulting in increased hydrolysis and antioxidant capacity of enzymatic hydrolysates. U-H treated BMP exhibited the highest surface hydrophobicity (924.5 ± 1.0), zeta potential absolute value (18.88 ± 0.11 mV), hydrolysis degree (54.5 ± 1.6%), and antioxidant activity, but the lowest α-helix (21.84 ± 2.61%), intrinsic fluorescence spectrum intensity, total sulfhydryl (7.24 ± 0.07 µmol/g), and mean particle size (182.57 ± 2.23 nm). Therefore, U-H might be a promising pretreatment to prepare bioactive peptide.
Gnrhr-related Central Hypogonadism With Spontaneous Recovery-case Report
Authors: Schweiger Darja Šmigoc , Povše Maja Davidović , Podkrajšek Katarina Trebušak , Battelino Tadej , Stefanija Magdalena Avbelj
Published: May 2022

Introduction: Congenital hypogonadotropic hypogonadism (CHH) is a clinically and genetically heterogeneous disease characterized by absent or incomplete puberty and infertility. Clinical characteristics are secondary to insufficient gonadotropin secretion, caused by deficient gonadotropin-releasing hormone (GnRH) production, secretion, or action. Loss-of-function variants of the gonadotropin-releasing hormone receptor (GNRHR) are associated with CHH without anosmia. CHH was previously considered a permanent condition, but in the past two decades, cases of spontaneous recovery of CHH have been reported. The reversal of hypogonadism in CHH is currently unpredictable, and can happen unnoticed. Case presentation: The male proband was diagnosed with CHH due to compound heterozygosity for two previously reported pathogenic missense variants in the GNRHR gene, NM_000406.2:c.416G>A (NP_000397.1:p.Arg139His) and c.785G>A (p.Arg262Gln) at 16 years of age. In addition to arrested partial puberty, he had a low testosterone level, gonadotropins in the range of early puberty, and a normal inhibin B level. A therapy with increasing doses of intramuscular testosterone undecanoate was received for 2.5 years, while there was no change in testicular volume. At the age of 19 years, testosterone supplementation was interrupted. During the next two years, he had spontaneous pubertal development to achieve a testicular volume of 20 mL, with normal adult levels of gonadotropins and testosterone. Conclusions: Genetic diagnostics can help discriminate congenital hypogonadotropic hypogonadism, deserving therapeutic intervention, from the self-limited constitutional delay of growth and puberty. Patients with GNRHR associated hypogonadism can experience spontaneous recovery of the hypothalamic-pituitary-gonadal axis. Spontaneous testis enlargement in patients with central hypogonadism not taking gonadotropins or pulsatile GnRH therapy can indicate recovery of hypogonadism.
Effects of Ni-flash coating on hydrogen evolution, ad/absorption, and permeation behaviors of advanced high-strength steel during electrogalvanizing
Authors: Kim Sung Jin , Bang Hye Rin , Park Jin Sung
Published: May 2022

The effects of a thin Ni-flash coating on hydrogen evolution, ad/absorption, and permeation of advanced high-strength steel were examined for a deeper understanding of the hydrogen infusion behavior in the steel substrate during electrogalvanizing. The electrochemical permeation technique and impedance spectroscopy were used under cathodic polarization in a step-up manner. In addition to the electrochemical analyses, the hydrogen microprinting technique was employed to identify the distribution of Ag particles (locating hydrogen atoms) in the electrogalvanized steels with and without a thin intermediate Ni-layer. The results revealed that despite the higher hydrogen evolution rate on Ni-layer than on bare steel, the intermediate Ni-layer decreased the hydrogen infusion considerably in the steel substrate during electrogalvanizing, due primarily to the lower hydrogen ad/absorption rate on the Ni-layer, and the predominant hydrogen trapping at the multi-interfacial areas of the Zn-layer/Ni-layer/steel substrate. These results could provide insights into the precise role of a thin Ni-flash coating on the resistance to hydrogen embrittlement of ultra-high-strength steel alloys during electrogalvanizing.
Peer researchers’ experiences of a co-produced research project on supported decision-making
Authors: Webb Paul , Falls David , Keenan Fionnuala , Norris Barbara , Owens Aine , Davidson Gavin , Edge Rosalie , Kelly Berni , McLaughlin Aisling , Montgomery Lorna , Mulvenna Christine , Irvine Rebecca Shea
Published: May 2022

BackgroundMaking decisions about your own life is a key aspect of independence, freedom, human rights and social justice. There are disabled people who, without support, would be assessed as incapable of making certain decisions but with the appropriate support are capable of making those decisions and so to not provide that support infringes their rights, undermines their autonomy and reinforces their exclusion from society. However, there is limited research evidence available about disabled people’s experiences of the range of approaches provided to support decision- making. This article will explore the experiences of four peer researchers who co-produced a research project on how people have, or have not been, supported to make their own decisions. Two of the peer researchers have experience of mental health problems and two are people with intellectual disabilities. MethodsThe peer researchers interviewed 21 people with mental health problems and 20 people with intellectual disabilities to gain an in-depth understanding of their experiences and preferences for how decision-making should be supported. Peer researcher experiences at each stage of the study from design to analysis were explored using data collected from the peer researchers via blogs written at early stages of the study, discussions at team meetings as the fieldwork progressed and at a final workshop at the end of the study which gave the peer researchers the opportunity to focus on their overall reflections of being a peer researcher. The article also discusses motivations to undertake the peer research role, the process of co-production and the challenges negotiated during the study. ResultsThe peer researchers reported a number of positive effects of being involved in the research project which included improvements in skills and self-confidence. ConclusionsThe peer researchers’ involvement challenged assumptions about the inability of people with intellectual disabilities and/or mental health problems to participate proactively in a research project whilst also highlighting the importance of training for all team members.
Effect of Intensive Short-term Functional Strength Training on Physical Fitness Variables of National Kho-kho Players
Authors: Kumar Manish , Rizvi Moattar , Sharma Ankita , Arora Sumit , Saini Preeti
Published: May 2022

Background: Kho-Kho is unique from any other game where in the players are arranged in random manner chasing the opponent and need to be very quick. However, Kho-Kho is a team game, but still individual ability shows a vital role in the victory of game. Cultivating and maintaining the physical fitness is becoming one of the most important aims for any sports training. This study is aimed to evaluate the effect of intensive short-term functional strength training on functional movement, balance, and agility amongst the National Kho-Kho players.Method: Sixty National Kho-Kho players (35 males and 25 females) were recruited for the Kho-Kho camp who were included in the study. Two weeks training session based on strength and balance was given to the players and following this post data was obtained for functional movement, balance and agility before and after the training respectively. Result: There were significant improvement in FMS composite scores after 2 weeks of intervention (p=<0.001) both in male and female Kho-Kho players. After 2 week of intervention there were significant improvement was observed in Balance [Static with open eye (p=0.043), with close eye (p=<0.001 and Dynamic for both feet (p=<0.001), for single foot comparison (p=0.032)], as well as significant changes was observed in agility [SEMO (p=<0.001). 40m run (p=0.808), Illinois test (p=<0.001)]. Conclusion: The conclusion of this study is that short duration Functional Strength Training gives the effect on Functional movement screening, Balance and Agility of national KHO-KHO players. This can help to maintain body strength as well as proprioception. Early detection in lack of Functional movement, balance and Agility can reduce the risk of injury. As short duration, functional strength training helps to develop the mobility, balance, stability and strength of individual, which in turn can help the Kho-Kho players for the improved performance.
Correlation between health of Hungarian adults and the 6-minute walking test
Authors: Gordos Mónika , Wilhelm Márta
Published: May 2022

Backround
Previous studies of health and wellbeing of the Hungarian adult population primarily focused on illnesses, alcohol consumption, smoking habits, the use of health services and other health related costs, economic and social problems and life expectancy at birth. Expected life time without limitations predicted at birth in Hungary lags behind other countries, according to 2019 WHO data, having the 76th place.
Aims
The aim of our study was to measure health related fitness of a Hungarian adult sample with the aid of 6MWT and correlate their performance with anthropological data.
Methods
143 healthy volunteer subjects participated in the survey (45 male and 98 female), the average age was: 45.31 ± 9.42 year.
Results
Anthropometric data greatly diverged from the normal range in both genders. Average deviation was 59.28% in bodyweight; 56.07% in BMI; 57.38% in body fat percentage; 56.09% in WH ratio. Results of the 6MWT (647.60 ± 20.27 m, average VO₂max was 45.77 ± 5.12 ml/kg/min)) and the 6MWT results lagged slightly behind expecyed velues (771.12 ± 78.59 m).
Conclusion
Exploring the primary reasons of these results are very important, but offering appropriate training and lifestyle programs would help improving the health related fitness of Hungarian adults.
Chemical characterization and biological effect of exopolysaccharides synthesized by Antarctic yeasts Cystobasidium ongulense AL101 and Leucosporidium yakuticum AL102 on murine innate immune cells
Authors: Rusinova-Videva Snezhana , Ognyanov Manol , Georgiev Yordan , Petrova Ani , Dimitrova Petya , Kambourova Margarita
Published: May 2022

The current study aimed to investigate exopolysaccharides (EPSs) produced by two Antarctic yeasts isolated from soil and penguin feathers samples collected on Livingston Island (Antarctica). The strains were identified as belonging to the species Leucosporidium yakuticum (LY) and Cystobasidium ongulense (CO) based on a molecular genetic analysis. The EPS production was investigated at submerged cultivation. Different chemical, chromatographic, and spectral analyses were employed to characterize EPSs. LY accumulated 5.5g/L biomass and 4.0g/L EPS after 120 h of cultivation, while CO synthesis 2.1g/L EPS at the end of cultivation and biomass amount reached 5.5g/L. LY-EPS was characterized by a higher total carbohydrate content (80%) and a lower protein content (18%) by comparison with CO-EPS (62%, 30%). The LY-EPS mainly consisted of mannose (90 mol%), whereas CO-EPS had also glucose, galactose, and small amounts of uronic acids (8-5 mol%). Spectral analyses (FT-IR and 1D, 2D NMR) revealed that LY-EPS comprised a typical β-(1→4)-mannan. Branched (hetero)mannan, together with β/α-glucans constituted the majority of CO-EPS. Unlike LY-EPS, which had a high percentage of high molecular weight populations, CO-EPS displayed a large quantity of lower molecular weight fractions and a higher degree of heterogeneity. LY-EPS (at a concentration of 100 ng/mL) elevated significantly interferon IFN-γ production in splenic murine macrophages and NK cells. The results indicated that newly identified EPS might affect IFN-γ signaling and in turn, might enhance anti-infectious responses. The data obtained also revealed the potential of EPSs and yeasts for practical application in biochemical engineering and biotechnology.
Controlled Electronic and Magnetic Landscape in Self-Assembled Complex Oxide Heterostructures
Authors: Park Daesung , Rata A. Diana , Dahm Rasmus , Gan Yulin , Maznichenko Igor , Ostanin Sergey , Trier Felix , Choi Woo Seok , Choi Chel-Jong , Kim Young Heon , Rees Gregory , Chu Kanghyun , Gíslason Hafliði , Buczek Pawel , Mertig Ingrid , Ionescu Adrian , Ernst Arthur , Dörr Kathrin , Muralt Paul , Pryds Nini
Published: May 2022

Complex oxide heterointerfaces contain a rich playground of novel physical properties and functionalities, giving rise to emerging technologies. The electronic states at the interface include strongly correlated interactions, governed by distortions of crystal symmetry, lattice strains, electronic reconstruction, and defect orders. Here, we demonstrate that self-assembly approach has an ability to control the electronic and magnetic landscape using interface engineering of complex oxide LaAlO3(1-x):LaBO3(x) (LABO) nanocomposite thin film heterostructure on SrTiO3(001). A 2D layer-by-layer growth yields atomically abrupt interfaces where vertically aligned magnetic structures (3D) are spontaneously formed in the LABO/SrTiO3 heterostructures. This 2D-3D transient structural assembly is primarily driven by the composition ratio, leading to the coexistence of low-dimensional high-mobility electron gas and magnetic ordering. We further demonstrate an effective way to tune the magnetism for triggering notable magnetoelectric coupling effects. Our work paves the way for designing oxide nanocomposite heterostructures via a self-assembly approach with multifunctional coupled phenomena.
High Angle Mass Flux of an Electrospray Plume
Authors: Collins Adam Leigh , Wright Peter Lloyd , Uchizono Nolan Michael , Wirz Richard Edward
Published: May 2022

High-resolution mass flux measurements of an electrospray plume are reported at high (> 30º) angles, which are relevant to direct impingement of downstream electrodes. Interrogation of the plume edge greatly reduces uncertainty in electrospray device lifetime estimation related to mass flux to electrode surfaces. An angularly-actuated Thermoelectric Quartz Crystal Microbalance (TQCM) provides resolution down to ∼2 pg cm−2 s−1 , allowing the highest resolution mass flux measurements of an electrospray plume to be reported herein. In-situ microscopy of the electrospray meniscus revealed changes to the electrode lines-of-sight of approximately 2° to 3° due to the increasing meniscus tip height with beam current. Using the TQCM measurements and previous QCM results, a data-driven model is proposed for estimating electrode impingement as a function of beam current and aperture line-of-sight, which quantitatively captures the rapid increase in mass flux at higher beam currents or at low angles. The results show it is possible to guarantee negligible electrode impingement within a specified range of throttle levels.
Primers for multiplex PCR identification for source of origin and pathogenic E.Coli contamination in meat samples: An electronic PCR experience
Authors: Kumari Monu , Banerjee Dibyajyoti , Bhattacharyya Rajasri
Published: May 2022

Meat fraud is an ongoing issue. So, Identification of meat adulterant as well as bacterial contamination is utmost need. Advance technology like Multiplex and digital droplet PCR are the two currently used methods for diagnosing contamination of meat. However, simultaneous testing of adulterant and bacterial contamination in livestock are not done profoundly. Here, we have design PCR primers which can be used to identify adulterant and bacterial contamination concurrently.
WITHDRAWN: Computational modeling of coupling exothermic and endothermic reaction processes in microchannel reactors for hydrogen production
Authors: Chen Junjie
Published: May 2022

Process miniaturization and microchannel reactor technology provide opportunities for improving chemical processing and provide improved process control in chemical synthesis. What is needed is a simple and direct way of optimizing reactor operation and design to combine the key variables such as reactor dimensions and catalyst thermal properties. The present study relates to a catalytic process of steam-methanol reforming for the production of hydrogen in a microchannel heterogeneous reaction system. Computational fluid dynamics simulations are performed with respect to various factors pertaining to the reactor system. The effects of catalyst thermal conductivity and channel characteristic length on reaction and transport processes are investigated in terms of efficiency and performance. Design recommendations are made to offer improvements in process capability and process control. The results indicated that the catalyst thermal conductivity and channel characteristic length are vital in determining the efficiency and performance of the reactor system. The microchannel design method provides greater product yield and permits using less steam and maintaining catalytic activity of the catalyst. Microchannel reactors can provide unique opportunities for reaction and chemical engineers to control transport phenomena to produce extremely efficient chemical reactors. The performance of hydrogen production is controlled by mass transport and thermal transport through the reaction medium. Hydrogen production can be optimized by precise control of the parameters that determine the overall efficiency of the reaction. Catalytic combustion reactions occur rapidly and are particularly difficult to control with precision. Microchannel reactors can provide sufficient residence time to achieve the desired conversion, provide sufficient mass transfer rate of reactants and products on the catalyst surfaces, allow for conditions where heat is transferred effectively, and provide an effective method for controlling temperature in a safe operating window.
Effect of Lanthanum doping on the specific gas sensing behavior on BaSnO3
Authors: Bajpai P. K. , Bajpai Sharmila , Patil D.R.
Published: May 2022

La-doped Ba1 − xLaxSnO3 (x = 0.0, 0.01, 0.02, 0.03) powders were prepared by solid-state reaction method for improving their specific gas sensing properties. Highly pure single perovskite phase n-type BaSnO3 (BSO) ceramics were synthesized after sintering at 1300°C. The materials were characterized by X-ray diffraction (XRD). Ba1 − xLaxSnO3 (BLSO) compositions stabilized in cubic crystalline phase (space group Pm-3m). Lattice constant variation with La-doping is attributed to two competing effects of ionic radii variation as well as reduction of B-site valence. Microstructure and elemental analysis exhibited La being incorporated into the lattice and doping induced surface homogeneity enhancing. Raman measurements give phonon bands that are Raman forbidden under cubic symmetry suggesting that local structural distortion occurs with average cubic structure. Thick films were used for measurng the gas sensing behavior (selectivity and sensitivity) for LPG, CO2, C2H5OH, NH3, H2, Cl2, H2S. The compositions show the selective response for Ammonia and Ethanol at 100°C and room temperature (27°C) respectively. Ba1 − xLaxSnO3 (x = 0.02) composition at an operating temperature of 100°C show maximum response of 10.67 for ammonia (NH3) whereas Ba1 − xLaxSnO3 (x = 0.01) composition at 27°C shows maximum response of 18.61 for ethanol (C2H5OH) at 100 ppm gas concentration. The gas sensing mechanism and the selectivity enhancement due to La-doping are discussed.
Capital adequacy determinants of Indian banks listed on the Bombay Stock Exchange
Authors: Ahmed Mareai Senan Nabil , Ali Belhaj Fozi , Mohammed Al-Matari Ebrahim , Abdulaziz Saleh Al-Faryan Mamdouh , A. Al-Homaidi Eissa
Published: May 2022

This study examines the influence of corporate-specific factors and external factors on capital adequacy of Indian banks listed on the Bombay Stock Exchange (BSE). This study used a GMM estimation (pooled, fixed, and random) for the period 2009–2018 to study thirty-seven Indian listed commercial banks. Banks’ capital adequacy (CAAD) is used as a dependent variable measured by equity to total assets. While corporate specifics factors include bank size, asset quality, liquidity ratio, deposit ratio, asset management, operating efficiency, return on assets, net interest margin, and non-interest income, external factors are economic activity, exchange rate, and interest rate. The results of this paper found that the deposit ratio, asset management, bank size, and operating efficiency are the main factors influencing banks’ CAAD of Indian listed firms during the period of the study. The outcomes revealed that the deposits ratio, asset management, and bank size have a negative and significant influence on banks’ CAAD, while operating efficiency has a positive and significant impact on CAAD. In terms of external indicators, the results revealed that gross domestic product and interest rate have a negative and significant effect on CAAD of Indian listed banks, except that the exchange rate has a positive and significant influence on CAAD. AcknowledgmentThe authors would like to thank the Arab Open University, Kingdom of Saudi Arabia, for supporting this research paper.
ROBÓTICA EDUCACIONAL, ENSINO DE QUÍMICA E APRENDIZAGEM COOPERATIVA: UMA PROPOSTA PARA O CURSO DE ENSINO SUPERIOR EM ENGENHARIA CIVIL
Authors: Pinheiro Ricardo , Soares Márlon
Published: May 2022

EDUCATIONAL ROBOTICS, CHEMISTRY TEACHING AND COOPERATIVE LEARNING: A PROPOSAL FOR THE COURSE OF UNIVERSITY EDUCATION IN CIVIL ENGINEERING. Students, generally, are afraid of studying chemistry because they understand that it is a very complex area of knowledge and that it doesn’t has use in daily lives and in intended profession, which is a problem we identified in a Civil Engineering course. With this, we proposed a project in this course, based on educational robotics and educational cooperation, with the intention to form a group of students and a teacher to make a robot involving chemical knowledge in civil construction. The group made a robot, using an Arduino kit and material recycling, to identify electrochemical corrosion in concrete structures. We conducted a case study about the group through the analysis of gestures, products made, and notes in a notebook, from which two cooperative categories emerged: planning and application. From these categories, we identified that the students had their cognitive structures unbalanced by difficult situations, trials, errors, and diverse knowledge. The formation of a new equilibrium condition resulted from individual and social developments in constant interdependence, allowing the joint construction of knowledge, whose complexity increased during the process and culminated in the realization of the robot. All these aspects characterized cooperative learning.
Dynamics of demand for skills and industrial structure of economy: Developed and developing countries
Authors:   National Research University Higher School of Economics, Telezhkina Marina
Published: May 2022

The paper considers changes in the structure of employment by skill level in countries. Differences in dynamics of the shares of employed with high, medium and low skill levels is traditionally explained by differences in exposure to routine-biased technologies, participation in international trade, exposure to offshoring in the country. The current paper contributes to the literature about the drivers and determinants of changes in structure of employment by skill level considering the industrial structure to be the one of main factors. We assume that the dynamics of employees with high, medium and low skill levels depends on the shares of agriculture, manufacturing and service in the economy. Service industry has the largest share of employment; it is highly competitive and prone to the growing influence of large scale technologies. Using the data of 218 countries for the period 1989–2019 we prove that the greater the service industry in the economy, the higher the share of employed in high skill occupations in absolute value and relative to the share of employed in medium skill occupations. The faster the growth of service industry, the higher the growth rate of the number of employed in medium and high skill occupations. The share of manufacturing in GDP, the value of GDP per capita are the significant determinants of the dependent variables. We highlight substantial differences in the models of the structure of employment by skill level and its dynamics in the developed and developing countries, the oil exporting countries. The research results make it possible to identify and explain trends in structure of employment by skill level by the peculiarities of production in economy.
France’s security strategy for the 21st century
Authors: Zięba Ryszard
Published: May 2022

After the end of the Cold War, France issued the first document defining its national security strategy only in 1994. In the following years, despite its involvement in NATO and European Union enlargement, France did not publish any documents defining its security strategy. Only when Europe and the world found themselves in the process of reconfiguration of the international order at the end of the first decade of the 21st century did France begin to issue extensive documents defining its defense and national security strategy. As international terrorism became the greatest threat to France, the first document published in 2006 dealt with its position regarding this global phenomenon. Subsequently, White Papers on Defense and National Security were published in 2008 and 2013, followed by the Strategic Review of Defense and National Security in 2017. These documents define threats and challenges to the security of France, as well as its goals, and means and methods for strengthening it. They make up a broad understanding of the security of the state, society and the individuals, and international security. They show the programming of France as a European and world power. The author draws attention to some similarities and differences with the national security strategy of the Russian Federation. The analysis is conducted using the neorealist approach.
A Chave é a Questão
Authors: Azevedo / Pazciência Paulo
Published: May 2022

Nota sobre a ilustração.
Para Uma Antropologia do Caos
Authors: Fortunato Rêgo De Medeiros Lucas , Jadson Silva Maia Francisco , Galeno Alexsandro
Published: May 2022

Neste artigo é apresentado um diagnóstico do presente na intenção de contribuir para uma antropologia do caos, perspectiva aberta pelos estudos de Claude Lévi-Strauss sobre a civilização ocidental. Para tanto, a noção de progresso e o valor da tecnologia que nortearam os projetos da civilização são problematizados. Por fim, propomos a reforma do pensamento e a construção de uma ética ecosófica planetária para superar os impasses da atualidade. Palavras-chave: Antropologia. Civilização. Progresso. Tecnociência. Caos. Ecosofia.
Sete Interrogações Para a Ciência Contemporânea
Authors: Baitello Junior Norval
Published: May 2022

Neste artigo, a ciência, a mídia e a cultura produzidas pelo capitalismo são colocadas em perspectiva por uma reflexão ensaística, questionadora e cética. Temas atuais como aparelhamento das ciências, desenraizamento do presente e poluição imagética são tratados como efeitos de potências destruidoras inerentes ao poderio da civilização capitalista. Palavras-chave: Giftschrank. Ciência Aparelhada. Produção de Ignorância Sistematizada. Desenraizamento do Presente. Fundamentalismo.
How Can We Enter in Dialogue?
Authors: Nicolescu Basarab
Published: May 2022

Can we really dialogue?
Desenvolvimento do Conhecimento Contemporâneo
Authors: Amorim Ivair Fernandes de
Published: May 2022

O presente trabalho consiste em uma breve reflexão do panorama científico atual. Revendo os preceitos teorematizados da lógica cartesiana vigente durante anos, evidencia seu declínio e contestação. Novas abordagens e perspectivas se delineiam diante do crescente trabalho dos investigadores científicos na busca de uma melhor compreensão da natureza complexa do real. Este trabalho utiliza uma série de textos e busca tecer um alinhavo reflexivo que possa nos aproximar do contexto científico atual que cada vez mais admite a opacidade do real. As ideias de Gaston Bachelard tomadas por este trabalho ajudam a entender a construção de um novo espírito científico, espírito fundamental para a compreensão de uma realidade complexa e opaca. Finalizando, o estudo reflexivo conta com exemplos de importantes teóricos, em diferentes áreas do conhecimento, que têm adotado uma nova postura e um novo espírito científico. Em suma, este trabalho ajuda-nos a rever o mito da verdade absoluta.
Contribuição das Ferramentas do Marketing Digital Para a Vantagem Competitiva em uma Empresa de Pequeno Porte
Authors: Santos Luciclaudia Daniel dos , Vieira Mateus Lima , Maurício Isoni Miguel
Published: May 2022

A presente pesquisa se delimita em investigar a contribuição das ferramentas do marketing digital para a vantagem competitiva no contexto das micro e pequenas empresas. Para tal, fez-se uso de entrevista com a gestora da Loja Surya na cidade de Patos-PB e de um survey aplicado com 20 de seus clientes se constituindo, assim, em um estudo de caso cujos dados foram submetidos à análise de conteúdo. Como resultados notou-se que a empresa estudada está em uma ambiente cuja diferenciação é baixa e com clientes altamente conectados mas que, mesmo assim, faz uso mínimo das possibilidades proporcionadas pelo marketing digital e suas ferramentas sendo percebido conforme os participantes do questionário um padrão semelhante em empresas com o mesmo modelo de negócio. Nesse sentido, a instituição estudada ainda não consegue fazer uso das ferramentas do marketing digital para obtenção de vantagem competitiva, uma vez que o seu uso em si não a diferencia em seu setor nem há análise suficiente dos dados obtidos online para tomada de decisões que se traduzam em melhorias no negócio.
Amor Solitário no Mundo Virtual
Authors: Moreira da Silva Allyson Darlan , Do Nascimento Kelvis Leandro
Published: May 2022

A sociedade atual é marcada pelo capitalismo artista (LIPOVETSKY e SERRO, 2015) que captura o imaginário do sujeito através de símbolos e imagens ideais. Ao transformar emoções, desejos e sensações em mercadorias vendidas em lotes, o capitalismo artista está intimamente ligado com o aumento do mal-estar nos sujeitos contemporâneos. No que diz respeito aos laços amorosos na pós-modernidade, fruto de análises de autores como BAUMAN (2005), COSTA (1998), GIDDENS (1993), já não estamos mais sob o império hegemônico do amor romântico, nem podemos ser explicados apenas como produtores de um amor líquido. Neste artigo, propomos o termo “amor solitário” para tentar exemplificar as influências do capitalismo artista na produção do ideal amoroso na contemporaneidade. Fruto do individualismo exacerbado e do narcisismo extremo provocado pelo mercado, o amor solitário é o amor que se sente sozinho, em desamparo, sem conseguir estabelecer o vínculo que se espera.
Babel
Authors: Sousa Júnior Dantas
Published: May 2022

Esta obra do sociólogo polonês Zigmunt Bauman, juntamente com o jornalista e escritor italiano Ezio Mauro, tratam de temas contemporâneos como a globalização, a crise econômica, ideologias e da desconfiança das pessoas dos sistemas políticos. Todos estes problemas causados ou vividos na incerteza e na liquidez da modernidade. O atual contexto da era da conectividade, da sociedade em rede, de um momento de enfraquecimento das relações sociais e da decadência da democracia.
Bolsonarismo
Authors: Musse Ricardo
Published: May 2022

Resenha do livro Bolsonarismo: ideologia, psicologia, política e temas afins de LYRA, R. P.
Conceito de Técnica em Ortega y Gasset, Martin Heidegger e Álvaro Vieira Pinto
Authors: Bazzanella Sandro Luiz , De Fáveri José Ernesto
Published: May 2022

A técnica se tornou, na contemporaneidade, um fim em si mesmo. Em sua condição categórica, se apresenta como o modo de vida determinante que nos envolve a partir das regras da racionalidade articulada com base em critérios de funcionalidade e de eficiência. Sob tais pressupostos, o objetivo deste artigo é contribuir com o debate a respeito da questão da técnica e suas imposições sobre a forma da relação dos seres humanos com o mundo, consigo mesmos e como outros seres humanos. Nessa direção, participam deste debate o filósofo espanhol José Ortega y Gasset (1883-1955), mais especificamente em sua obra Meditação da Técnica (1963), o filósofo alemão Martin Heidegger (1889-1976), a partir do texto A questão da técnica, publicado na segunda metade dos anos 50 do século XX, e o filósofo brasileiro Álvaro Vieira Pinto (1909-1987), em sua obra O Conceito de Tecnologia v. I (2005). Salvaguardadas as diferenças teóricas, conceituais, o que aproxima tais pensadores em torno da questão da técnica é o fato de terem vivenciado os conflitos mundiais das primeiras décadas do século XX, os horrores perpetrados pela racionalidade técnica instrumental nos campos de concentração e a condição subdesenvolvida dos povos do terceiro mundo. Questões que se desenrolaram ao longo do século XX, ceifando vidas, impondo sofrimento e miséria às culturas, aos povos e aos países subdesenvolvidos. Uma versão preliminar deste artigo foi apresentada no 2º Colóquio Álvaro Vieira Pinto, no dia 08 de dezembro de 2017, na Universidade Federal do Paraná (UFPR).
Artista e as Interpretações da Modernidade
Authors: Aguiar Jórissa Danilla Nascimento
Published: May 2022

Propomos uma leitura crítica sobre a modernidade a partir da ótica benjaminiana, esclarecendo que a sua escolha por Charles Baudelaire foi motivada pelo fato de ser um dos artistas porta-vozes de interpretações sobre esta época, na qual artistas teorizavam poeticamente sobre o objeto de arte, suas condições de produção, suas técnicas e a busca do novo em meio à imprevisibilidade ressaltada com a modernidade. Como Baudelaire relaciona temas como o desenvolvimento do capitalismo e a subalternização das pessoas e o esfacelamento do mundo moderno pela via da arte, a partir de uma consciência melancólica que cruamente desnuda as relações sociais, destacando o tom de racionalidade trazido pelos autores e as visões do cotidiano marcado pela contraditoriedade da vida moderna encaradas de forma melancólica. Pois, a importância de Baudelaire para inaugurar a modernidade lírica crítica a um estilo de vida que aparta as pessoas umas das outras, do mundo, promovendo a fragmentação e a dispersão como premissas primeiras.
Sobre o Cansaço da Sociedade
Authors: De Oliveira Silva Tadeu , Santos Adelino José Waldeyr
Published: May 2022

Resenha acadêmica da obra Sociedade do Cansaço