bluuebunny/crossref_metadata_2025 huggingface dataset:
THE INTRIGUING LINK BETWEEN ORAL HEALTH AND CARDIOVASCULAR WELLBEING: A CALL FOR PROACTIVE ACTION
Authors: Edward Majani , Jamal Syeda Maham , Madimo Alex , Ogunfolaji Oloruntaba
Published: March 2024

Mounting evidence reveals a captivating connection between oral health
and cardiovascular health, prompting a surge in scientific curiosity and
potential solutions for reducing global cardiovascular disease burden.
This paper delves into this intricate relationship, highlighting the
prevalence of oral diseases and their association with various systemic
conditions. Studies exploring the potential link between poor oral
hygiene, particularly periodontal disease, and cardiovascular illnesses
like heart attack, stroke, and heart failure are examined. While the
precise causal mechanisms remain under investigation, potential
explanations involving chronic inflammation, shared risk factors, and
even genetic susceptibilities are discussed. Despite the lack of
definitive proof that treating gum disease directly prevents heart
problems, the robust correlation necessitates prioritizing good oral
hygiene practices. Regular brushing, flossing, and dental checkups are
emphasized as preventive measures against periodontal disease and its
potential contribution to cardiovascular risks. Addressing shared risk
factors like diabetes and smoking further strengthens the protective
shield against both oral and heart health concerns.The paper underscores
the importance of public health initiatives promoting oral hygiene
awareness, particularly among vulnerable populations facing limited
access to dental care. Additionally, the crucial role of ongoing
research in elucidating the exact mechanisms linking oral and
cardiovascular health is highlighted, paving the way for future
development of targeted interventions and personalized prevention
strategies. In conclusion, while the mysteries surrounding the precise
cause-and-effect relationship between oral and cardiovascular health
persist, the compelling evidence presented demands a proactive approach.
Prioritizing good oral hygiene, addressing shared risk factors, and
advocating for accessible dental care stand as powerful tools in our
collective fight against these prevalent health challenges.
Energy metabolic profile in oral potentially malignant disorders and oral squamous cell carcinoma
Authors: Gonçalves Francisca , Bittencourt Leonardo , Barbosa Silvia , Diel Leonardo , Bernardi Lisiane , Matte Cristiane , Lamers Marcelo
Published: March 2024

We hypothesized that cell energy metabolic profiles correlate with
normal, dysplastic, and tumor cell/tissue statuses and may be indicators
of aggressiveness in oral squamous cell carcinoma (OSCC) cells.The
energy-related proteins that were differentially expressed in human OSCC
fragments (n=3) and their adjacent epithelial tissue (TAE) were verified
using mass spectrometry. Immunohistochemistry for 4-hydroxynonenal
(4-HNE) was performed to evaluate the oxidative stress patternsin OSCC
(n=10), epithelial dysplasia (n=9), and normal epithelial (n=4)
biopsies. The metabolic modulation of OSCC aggressiveness was
investigated in human OSCC cell lines with different levels of
epithelial–mesenchymal transition proteins. All OSCC fragments
exhibited an increase in glycolysis-related proteins and a decrease in
mitochondrial activity compared to the TAE region (p<0.05),
probably due to the downregulation of pyruvate dehydrogenase and
antioxidant proteins. Additionally, the OSCC cell line with a
mesenchymal profile (SCC25) had a lower mitochondrial mass and membrane
potential and generated lower levels of reactive oxygen and nitrogen
species than the TAE region. When we analyzed 4-HNE, the reactive
species levels were increased in the epithelial regions of OSCC and
potentially malignant lesions. A decrease in the levels of
4-HNE/reactive species was observed in the connective tissue underlying
the dysplastic regions and the OSCC invasion zone.Thus, aggressive OSCC
is associated with high glycolytic and oxidative metabolism and low
mitochondrial and antioxidant activities, which vary according to the
differentiation level of the tumor cells and the stage of
carcinogenesis.
Incidence of vestibular schwannoma in Finland, 1990–2017
Authors: Iivanainen Aino , Raitanen Jani , Auvinen Anssi
Published: March 2024

Background: An increasing trend in incidence of vestibular schwannomas (VS) has been reported, though not consistently, across populations. 
Materials and methods: We obtained data from the Finnish Cancer Registry on 1,149 VS cases diagnosed in 1990–2017 with tabular data up to 2022. We calculated age-standardised incidence rates (ASR) overall, by sex, and for 10-year age groups. We analysed time trends using Poisson and joinpoint regression.
Results: The average ASR of VS in Finland during 1990–2017 was 8.6/1,000,000 person-years for women and 7.5/1,000,000 for men. A declining trend was found with an average annual percent change of −1.7% (95% confidence interval [CI]: −2.8%, −0.6%) for women, −2.2% (95% CI: −3.6%, −0.7%) for men, and −1.9% (95% CI: −2.9%, −1.0%) for both sexes combined. The ASR in women was 11.6/1,000,000 person-years in 1990 and it decreased to 8.2/1,000,000 by 2017. Correspondingly, the incidence in men was 7.1/1,000,000 in 1990 and decreased to 5.1/1,000,000 by 2017. Some decline in incidence over time was found in all age groups below 80 years, but the decline (2.3–3.1% per year) was statistically significant only in age groups 40–49, 50–59, and 60–69 years. In the oldest age group (80+ years), the incidence of VS increased by 16% per year. For 2018–2022, the ASR was 7.6/1,000,000 for both sexes combined, with a decline by −1.7% (95% CI: −2.3%, −1.2%) annually for the entire period 1990–2022.
Conclusion: In contrast to the increasing incidence reported in some studies, we found a decreasing trend in VS incidence for both sexes in Finland.
Topical Issues of Counteracting the Threats to National Security
Authors: Alekseeva M. V. , Filimonova E. A.
Published: March 2024

Introduction. One of the primary important objects for ensuring the national security of any state, as an independent and self-sustained subject of the system of global policy coordinates, is its sovereignty. The sovereignty is the fundamental category in formulating the principles of the national constitutional and international law. Ensuring the sovereignty is one of the most important functions and tasks of the modern Russian state. The article analyses the state policy and its legal basis for ensuring the national security, it focuses on the threats and crises in both the international and national security systems.

   The research is relevant due to studying the selective approach of some states to fulfilling their obligations to adhere to the commonly recognised principles of the international relations.

   It is emphasised, that although formally observed, the principle of national sovereignty of the states is constantly violated when referred to the weaker states according to the medieval “right of the strong”. The topical issues of counteracting the threats to national security are investigated. Attention is focused on the need to develop the measures aimed at timely and efficient prevention thereof.

   The aim of the study is to analyse the concept of “sovereignty”, identify the external and internal threats to the sovereignty of Russia and develop recommendations on the strategic national priorities.

   Materials and Methods. The research was conducted using the general and specific methods of scientific cognition, in particular, the dialectical method, content analysis of the normative legal acts, juridical comparativistics, as well as systemic, structural-functional, logical and other methods.

   Results. Within the research such concepts as “sovereignty”, “national interests of the Russian Federation and strategic national priorities” have been analysed. The assessment of the current state of the world order is given, as well as the directions and trends of its reform are studied. The external and internal threats to the sovereignty of Russia have been identified and strategic goals in the field of ensuring the national security have been outlined.

   Discussion and Conclusion. Based on the results of the conducted research, it was proved that the qualitative change of the methodological and conceptual foundations of the national and international security is required. To counteract the different national security threats, it is necessary to adhere to the national priorities, goals and the developed strategy. The present paper deems to be important for the Russian juridical science, as well as for the subjects of lawmaking and law enforcement.
Ensuring the Principle of Legal Certainty as a Way to Counteract the International Terrorism
Authors: Kuzubov A. A. , Maksimenko A. N.
Published: March 2024

Introduction. Due to its antisocial and destructive nature, terrorism constitutes a particular threat to the public, national and international security. It is one of the global problems of our time, which leads to the increased tension, has the high conflict potential and extremely negative effect on development and life of a society, a separate state and the globalcommunity on the whole. Cooperation between the national states and the international organisations for combating the international terrorism is most often restricted to the individual cases. In this context, the principles of law, which represent the concentrated essence of the universal values and ideals underlying the legal regulation of the social relationships, become particularly acute and relevant.

   The present article aims to analyse the theoretical and practical aspects of the principle of legal certainty in counteracting the international terrorism.

   Materials and Methods. The object of the study is the principle of legal certainty as a tool of counteracting the international terrorism. The dialectical method of cognition was used as the main research method, the general scientific methods of analysis, synthesis and the specific legal methods (empirical and legalistic) were also used.

   Results. It has been proved that the spread of extremism and terrorism constitutes a threat to the present day international and national legal order. The necessity to formulate a unified general definition of the concept of “terrorism” and to implement the principle of legal certainty in counteracting the international terrorism has been substantiated.

   Discussion and Conclusion. The research has revealed the need for an optimal and efficient solution for implementation of the non bis in idem (“not twice for the same”) principle with regard to the terrorist crimes (primarily of the international nature), endowing the universal jurisdiction over them, which allows criminal prosecution of the criminals regardless of their location, citizenship or territory, where the individual crime has been committed. The theoretical and practical value of the results obtained is the capacity thereof to be used both in the field of scientific research (for further theoretical study of the problems of counteracting the international terrorism) and in the field of law-making (for improving the Russian Federation legislation on counteracting terrorism). Bearing in mind future research, the special attention should be paid to the optimisation of the legal framework, enhancement of the regulatory legal mechanisms aiming to prevent in an optimal way the international terrorism as a social phenomenon.
Faktor-Faktor yang Berhubungan dengan Peran Usaha Mikro Kecil Menengah (UMKM) (Studi Kasus Pada Kelompok Pengrajin Tapis Mutiara di Kecamatan Negeri Katon Kabupaten Pesawaran)
Authors: Alda Mareta Karunia , Yanfika Helvi , Listiana Indah , Nurmayasari Indah
Published: March 2024

UMKM activity is one of the activities in the business sector that can be developed and has a consistent nature in the national economy. The purpose of this study was to determine the factors related to the role of Tapis Mutiara UMKM and to find out the acceptance of members of the Tapis Mutiara UMKM group in Negeri Katon District, Pesawaran Regency. This research was conducted in the District of Negeri Katon, Pesawaran Regency in November-December 2021. The respondents were 33 Tapis craftsmen who were members of the Pearl Tapis craftsman group in the Negeri Katon District of Pesawaran Regency. This research uses a case study method, namely a quantitative descriptive approach. The results showed the acquisition of Tapis Mutiara member acceptance within one year and the factors that were significantly related to the role of the Tapis Mutiara craftsman group in the Negeri Katon District, Pesawaran Regency, namely internal factors consisting of leadership ability, communication patterns and group atmosphere, while the internal factors consisted of leadership skills, communication patterns and group atmosphere. external, namely the existence of guidance, access to assistance for raw materials for filter products and the use of technology in product sales.

 

Keywords: UMKM, the Role of UMKM, Membership Acceptance
Tasapainon löytäminen
Authors: Saarinen Hanna
Published: March 2024

Jatkuvasti kehittyvällä digitaalisella aikakaudella sosiaalisen median rooli yritysten, erityisesti mikroyrittäjien, viestintästrategioiden kehittämisessä on tärkeämpää kuin koskaan. Mikroyrittäjien ulkoinen viestintä usein lähtee liikkeelle yrityksen tarpeista, tahdosta ja suunnittelusta. Laadukkaan viestinnän tulisi sisältää kahdensuuntaista vuorovaikutusta potentiaalisten asiakkaiden kanssa, sillä sosiaalinen media altistaa yrityksen julkisuudelle. Hallinnan puute ja yksisuuntainen viestintä ilman selkeää strategiaa altistavat yritykset resurssien tuhlaamiselle.
Phenomenological Approach to Media Art Environments
Authors: Scacco Lorella
Published: March 2024

Lectio praecursoria: Lorella Scacco’s art history dis­sertation “A Phenomenological Approach to Media Art Environments: The Immersive Art Experience and the Finnish Art Scene” was examined at the University of Turku on the 13th May 2023. The opponent was Dr, Museum Director Leevi Haapala (Museum of Contemporary Art Kiasma / Finnish National Gallery) and the custos was Professor Tutta Palin (University of Turku).
Boriding Effect on the Hardness of AISI 1020, AISI 1060, AISI 4140 Steels and Application of Artificial Neural Network for Prediction of Borided Layer
Authors: Özer Mehmet , Balikoglu Fatih , Demircioğlu Tayfur Kerem , Nehri Yunus Emre
Published: March 2024

Artificial neural network approach was used to predict the thicknesses of total (FeB+Fe2B), FeB and Fe2B borides layers of AISI 1020, AISI 1060, and AISI 4140 steels. Boronizing heat treatment was conducted in a solid medium comprising of EKabor®2 powders at 840–960 ˚C at 40 ˚C intervals for 2, 4, 6, and 8 hours. Optical microscope analysis of the borided layer revealed the saw-tooth (columnar) and planar morphology. The depth of the total (FeB+Fe2B), FeB and Fe2B boride layers was accurately predicted. For total boride layers generated by the artificial neural network model, the average error varied between 0.04 and 7.64 µm. Micro hardness values increased by 423% in AISI 1020, 336% in AISI 1060, and 411% in AISI 41040 after the boronizing process.
Evaluation of Obturating Material Removal from Root Canal by Hedstrom and Rotary Retreatment File
Authors: Bashar Farjana , Bashar AKM , Khan Mohammad Mahmudul Hasan , Hasin Atiyah , Asaduszaman Md , Hossain Mozammal
Published: March 2024

An in vitro investigation was conducted to assess the efficacy of Hedstrom and Rotary Retreatment File using Cone Beam Computed Tomography (CBCT) in removing obturating material from moderately to severely curved root canals. Thirty-six removed human molar teeth were split into two groups based on the canal curvature using the Schafer and Schneider method. Each group consisted of 18 teeth. Teeth in Group A had roots that were moderately curved (angles between 10 and 20 degrees), whereas teeth in Group B had roots that were severely curved (angles more than 20 degrees). Following decoronation, each root was ready for obturation using the appropriate rotary files, following the manufacturer’s recommendations. Using the CBCT image, the total surface area of the root canals in the axial cross-section and the volume analysis of the obturated area were calculated. H files were used to retreat half of each group, while Rotary (ProTaper) retreatment files were used for the other half, in accordance with their retreatment protocol. It was noted how long it took to reach the working length and remove all obturating items. Cone beam computed tomography and Auto CAD software are used to analyze the surface area and volume of any residual obturating material in the canal after it has been completely removed. An analysis of the data using the ANOVA test was conducted between four groups. When p < 0.05 was reached, it was deemed statistically significant. Rotary retreatment files were discovered to be the most efficient method for removing obturating material and to take the least amount of time to achieve working length. Compared to the Rotary retreatment file, the H file left greater residue in the root canal. Compared to moderately curved root canal groups, severely curved root canal groups have noticeably more residues. In all four groups, the apical part had more residues than the middle and coronal portions. The obturating substance in the root canal could not be entirely removed using any of the retreatment procedures. Furthermore, there was no advantage in terms of root-filling removal’s effectiveness.
Optimal Sizing and Techno-Economic Analysis of a Hybrid Power System for Postville
Authors: Farhadi Azadeh , Iqbal M. Tariq
Published: March 2024

Providing reliable and sustainable electricity to remote communities poses a significant challenge. Techno-economic feasibility of an off-grid hybrid renewable energy system for Postville, a remote Northern Labrador, Canada community, is presented in this paper. The study integrates solar photovoltaic panels, wind turbines, battery storage, and diesel generators into a hybrid system, analyzing various components and optimizing using advanced Homer Pro software. Simulation results demonstrate that the most optimized hybrid structure ensures a stable power supply while minimizing diesel generator operation, reducing fuel consumption. Economically, this system offers substantial cost savings, alleviating the financial burden on the community. The designed system consists of 435 kW PV, 500 kW wind turbine, 455 kW diesel generator, and 815 kWh batteries. The proposed system will generate power with a net present cost of $5.57 million. This research also contributes to the broader goal of creating sustainable energy solutions and improving the quality of life in remote communities.
Net Profit Margin Sebagai Moderator Tax Planning dan Corporate Social Responsibility pada Manajemen Laba
Authors: Yahya Adibah , Nurjanah Rina , Kustina Lisa
Published: March 2024

The purpose of this study is to determine the effect of Tax Planning, Corporate Social Responsibility (CSR) and Net Profit Margin (NPM) as a moderating variable on Profit Management. This research was conducted on manufacturing companies listed on the Indonesia Stock Exchange. This type of research is quantitative research, the population in this study are consumer goods manufacturing companies listed on the Indonesia Stock Exchange from 2018 to 2020, with a sample of 33 companies. The type of data in this research is quantitative data. Technique analysis in this research uses multiple linear regression and Moderated Regression Analysis (MRA). The test results show that Tax Planning positively affects earnings management, while Corporate Social Responsibility has a negative effect on earnings management. The MRA test results show that NPM cannot be used as a moderating variable between tax planning and CSR on earnings management.Keywords:  earnings management, corporate social responsibility net profit margin, tax planning
The Influence of Content Marketing and Product Knowledge on Generation Z Purchase Intention in Using Bank Syariah Indonesia services
Authors: Shalsabilah Nora Aulya , Firmansyah Fani
Published: March 2024

This study aims to find out how the correlation between content marketing and product knowledge and its impact on Generation Z's purchase intention towards Indonesian Sharia Banks. Data collection was carried out by distributing questionnaires to Generation Z students at UIN Maulana Malik Ibrahim Malang. This study adopts a quantitative approach with an explanatory design. Purposive sampling was used as a sampling technique, with a total sample of 100 participants. The measurement scale uses a Likert scale with five response levels. Data analysis includes validity tests, reliability tests, classical assumption tests, multiple linear regression analyses, t tests, F tests, and coefficient of determination tests using SPSS version 26.  The findings demonstrate that content marketing variables exert a significant influence on purchase intention, product knowledge variables have a significant impact on purchase intention, and both content marketing and product knowledge together significantly influence purchase intention.
Apakah Pertumbuhan Ekonomi mampu berjalan beriringan dengan Keberlanjutan Lingkungan?
Authors: Adry Melti Roza , Putri Dewi Zaini , Hernanda Tiara Aprilia Putri
Published: March 2024

The influence of human activity on the environment is becoming one of the world's significant problems. This arises because of growing concerns about the influence of each country's economic activity on the global environment. On the other hand, sustainable economic growth and human well-being are recognized as dependent on the benefits derived from the environment. This study aims to analyze the impact of economic growth on environmental quality in Indonesia.  To analyze the impact, regression analysis of polynomial panels was used by using panel data from 34 provinces in Indonesia in 2014 – 2019. The results found that non-linear GDP per capita only had a significant effect on the quality of land cover and water quality in Indonesia, but it did not have a significant effect on air quality. As for provinces in Java and Bali, it was found that non-linear GDP per capita only had a significant effect on air quality and land cover but did not have a significant effect on water quality in the area. Unlike provinces outside Java and Bali, GDP per capita non-linearly has a significant effect on air and water quality, but it does not have a significant effect on land cover quality. These results provide different recommendations for each  regional cluster.
Promising design solutions for drying liquid food systems
Authors: Maksimenko Yuriy Alexandrovich , Konnova Olga Ivanovna , Aleksanyan Igor Yurievich , Memedeykina Nataliya
Published: March 2024

An assessment of promising alternative design solutions for drying liquid food systems is given. Drying technology and techniques for removing moisture from liquid materials in a dispersed state have found widespread use in the food industry. The almost instantaneous drying of the sprayed particles in the coolant flow causes the formation of a developed phase interaction surface and acceleration of heat and mass transfer procedures, as well as the exclusion of overheating of the material due to intensive volumetric evaporation of moisture. A number of dryer designs have been developed to eliminate disadvantages (such as the large size of the dryers and their relatively high energy consumption and complexity of structural elements) or to reduce their impact on the course of the dehydration operation. The design specifics of devices for dewatering in the atomized state are due to the methods of supplying thermal energy, technological conditions and limitations, parameters of the dried product and the final powder substance, as well as its specific yield, peculiarities of the spraying operation, etc. The justification of the method of spray drying of liquid food material and the constructive use of the apparatus should be based on the study of a set of parameters and characteristics of the dehydration object, as well as on the construction and solution of a mathematical model of heat and mass transfer and exchange processes at the boundary of the phase section, as well as their mechanism in the development of a rational method of moisture removal to ensure the quality of finished products and energy- and resource saving. The proposed plant designs are recommended for organizing the drying process of liquid products, in particular for drying broths in fish production technologies.
Calculation of relaxation modes of the dehydrated surface layer of the whiting during the drying process
Authors: Ershov Mikhail Aleksandrovich , Kuranova Ludmila Kasimirovna , Ereschenko Viktor Valer'evich , Smirnova Irina Vladimirovna , Zhivlyantseva Iulia Viacheslavovna
Published: March 2024

During cold drying of fish, the surface layers, which have lost a significant part of the water, become compacted and prevent the diffusion of water from the inner layers of the fish to the surface. In order to restore the diffusion properties of the surface layer of fish, it is necessary to create conditions for the redistribution of moisture along the thickness of the object, for example, temporarily limit external mass transfer. To do this, reduce the temperature, the speed of air movement in the drying chamber and increase its relative humidity. Due to diffusion, water from the central layers of the fish will flow to the dehydrated surface layer and moisten it. As a result, the mass-conducting properties of the surface layer will increase. The purpose of this work is to study the effect of relaxation processes on changes in the thickness of the dehydrated surface layer of fish for the subsequent development of scientifically sound rational drying regimes. The calculation of moisture redistribution in this work was carried out under the condition (assumption) that there is no external mass transfer of moisture from the surface of the processing object. The kinetics curve and water distribution curves in the processing facility were constructed during the production of dried fish products in 2; 2.5; 13.5; 55 hours respectively. The average humidity of the whiting after dehydration lasting 2 hours was 333% in terms of dry matter. The thickness of the dehydrated layer S = 1.6 mm. After 1.5 hours of relaxation, the moisture on the surface of the fish increased from 272 to 330% and approached the average humidity of the sample. During dehydration of fish lasting 13.5 hours, the average moisture content of the sample per dry mass was 217%, the thickness of the dehydrated surface layer S = 0.9 mm. After 2.5 hours of relaxation, the moisture content on the surface of the layer was 174%. It was found that at the beginning of the drying process, the dry dehydrated layer has

a positive tendency to restore the lost moisture-conducting (diffusion) properties, but at the end of the drying process it takes more time to restore them. The paper proposes a method for calculating relaxation curves, which can be used to study the processes of moisture redistribution in the processing object in order to create rational drying modes.
Comprehensive assessment of environmental, social and managerial efficiency of enterprises in the fishing and fish processing industry
Authors: Sorokin Aleksandr Aleksandrovich , Maltseva Natalia Sergeevna
Published: March 2024

The purpose of the work is to form provisions for determining a comprehensive assessment of the effectiveness of the activities of a fishing and fish processing company in the field of ecology, social responsibility and in matters of management activities. When forming this assessment, indicators are taken into account that characterize the effectiveness of environmental protection measures; improvement of working conditions of employees, organization of corporate governance. To aggregate these characteristics, methods based on the position of the theory of fuzzy sets are proposed. The computing complex itself for processing information about the state of controlled parameters is implemented in the form of a hierarchical fuzzy inference system and an additional block that is used to distribute objects of analysis by state classes. The computing complex includes fuzzy inference systems based on the Sugeno algorithm. As a result of aggregation of the estimated parameters, two estimates are formed: one allows you to rank the analyzed objects, the second – to correlate the object of analysis with a certain class of state. The simulation showed that the computing complex has a high sensitivity: if at least one of the input variables is in the range of low (bad) values, this leads to a decrease in the value of the final score. This property makes it possible to exclude the occurrence of massaging of “bad” values of individual variables with “good” values of other variables. The results of the study confirmed the ability of the complex to distribute the objects of analysis by state classes. The results can be used for the development of corporate governance systems that are oriented for use in enterprises of the fisheries industry.
Characteristics of the structural changes of the ichthyofauna in the northern part of the Agrakhan Bay over the past 5 years
Authors: Ramazanova Javgarat Magomedovna , Grozesku Yulia Nikolaevna , Sudakova Nataliya Viktorovna
Published: March 2024

The northern part of the Agrakhan Gulf, which is a part of the Tersko-Caspian fishery complex of Dagestan, plays an important role in the formation of stocks of commercial fish species, having abundant spawning, nursery and wintering grounds. The efficiency of natural reproduction of fish is determined by the state of the hydrological and hydrochemical regime in the reservoir, which in recent years in this reservoir can be characterised as unfavourable. Studies carried out in North Agrakhan in the period from 2018 to 2022 have shown negative changes in the structure of ichthyofauna, manifested in a decrease in the number of juveniles of passable, semipassable, freshwater fish species and an increase in tuvodny fish of the lake-river complex. The number of juveniles of passable fish species has decreased almost twofold, kutum stocks have reached a critical level, the prevailing semi-passable fish species, which account for up to half of the total volume of recorded juveniles, are also decreasing, although to a lesser extent. Freshwater fish species are in a depressed state, the number of juvenile fish is decreasing from year to year, and has decreased more than twofold over the 5 years under study. The total number of segolets of low-value fishery lake-river fish species for 5 years increased 2 times and was 37% of the total volume of all fish species. In general, in the northern part of the bay the dominance of fish species in the northern part of the bay has become dominant among passable fish species - redfish, semipassable fish species - bream, freshwater fish species - redfish, lake-river fish species - redfish and crucian carp. Such species as kutum, pikeperch and practically all freshwater species are at the stage of extinction, mainly tench, which was recorded in catches only once.
Some aspects of the development of the internal control system at the enterprise
Authors: Gubachev N. N.
Published: March 2024

The Company establishes internal control as a measure to counteract violations and a tool to protect the interests of the company. Internal controls are procedures implemented by a company to prevent fraud, increase accountability, and ensure the integrity of financial data. Internal controls are unique to each company and are designed according to the size and structure of the company. Effective internal control is aimed at achieving the company’s goals and protecting the company’s interests. Internal control not only eliminates risks for the company, but also reduces unnecessary costs or efforts. Internal control ensures that the company complies with federal laws and regulations in the field of financial data management. Reliable internal controls can improve operational efficiency and ensure the reliability of financial statements during internal or external audits.
ЕФЕКТИВНІСТЬ ФІЗКУЛЬТУРНО-ОЗДОРОВЧИХ ЗАНЯТЬ З ЖІНКАМИ 45-50 РОКІВ НА ОСНОВІ СИСТЕМИ ЙОГИ І ПІЛАТЕСУ
Authors: Богуславська Вікторія Юріївна , Сальникова Світлана Володимирівна , Поляк Вадим Анатолійович
Published: March 2024

Сучасна фітнес індустрія пропонує безліч фізкультурно-оздоровчих систем. Проте методика занять фізичними вправами з жінками 45-50 років потребує особливого підходу, оскільки для жінок даного віку характерно зниження показників фізичних якостей, наявність соматичних захворювань та функціональних розладів систем організму. Мета дослідження: обґрунтувати ефективність фізкультурно-оздоровчих занять з жінками 45-50 років на основі системи йоги і пілатесу на функціональний стан їх кардіореспіраторної системи. Методи дослідження. В роботі були застосовані методи теоретичного рівня дослідження: аналіз, порівняння, індукція, дедукція, систематизація та узагальнення науково-методичної літератури, педагогічний експеримент, медико-біологічні методи, методи математичної статистики. Результати роботи. Обґрунтовано особливості експериментальної методики фізкультурно-оздоровчих занять, що передбачають комплексне застосування засобів, методів та методичних принципів пілатесу та йоги, підібраних в оптимальному співвідношенні; показано пов'язаний вплив фізичних, дихальних вправ, ментальних технік та звукового супроводу та використання індивідуальних комплексів профілактичних вправ, спрямованих на попередження загострень хронічних захворювань та функціональних розладів систем організму 45-50 років. Висновки. Застосування комплексної методики йоги і пілатесу є ефективною для поліпшення функціонального стану серцево-судинної та дихальної системи жінок 45-50 років та може безпечно використовуватися у фізкультурно-оздоровчій діяльності.
Mobiӏe Heaӏth Voӏuntary Counseӏing and Testing for HIV-AIDS Prevention: Literature Review
Authors: Holifah Ketut , Hariyati Rr Tutik Sri , Aryani Denissa Faradita
Published: March 2024

HIV or Human Immunodeficiency Virus is the virus that causes Acquired Immune Deficiency Syndrome (AIDS) HIV-AIDS is an infectious disease that can be transmitted through sexuaӏ intercourse (vaginaӏ, anaӏ or oraӏ). bӏood transfusions, contaminated needӏes. HIV prevention and intervention can be carried out by conducting Voӏuntary Counseӏing and Testing (VCT), nameӏy prevention and earӏy detection efforts to determine the status of a person who has been infected with HIV or not and is at risk, nameӏy through HIV/AIDS counseӏing and testing. The use of VCT so far is stiӏӏ ӏacking due to severaӏ factors, one of which is faciӏities and access. Therefore, the above conditions attracted the writer to find out the effectiveness of using VCT mHeaӏt in preventing HIV-AIDS. This study uses the ӏiterature review method by anaӏyzing 10 journaӏs reӏated to the use of mHeaӏth VCT. Journaӏ searches used the keywords Mobiӏe Heaӏth VCT and Voӏuntary Counseӏing and testing for HIV, in the journaӏ's onӏine database incӏuding PubMed, PubMed Centraӏ (PMC) and Cӏinicaӏ key. The incӏusion criteria for this study were journaӏs in Engӏish with a ӏimitation of the ӏast 5 years (2018-2022). Excӏusion criteria are ӏanguage other than Engӏish and journaӏ year under 2018. Research Resuӏts: Based on the anaӏysis of 10 journaӏs that have been carried out, the resuӏts show that mHeaӏth VCT has severaӏ advantages, nameӏy ӏow cost, easy access, effective, abӏe to detect earӏy and effectiveӏy prevent HIV. As a heaӏth technoӏogy, mHeaӏth is effective if appӏied in heaӏth services, especiaӏӏy in providing information, counseӏing, and testing or VCT to prevent and earӏy detection of HIV.
Stanowisko polskich ekspertów w sprawie praktycznych aspektów leczenia kladrybiną w tabletkach
Authors: Morawiec Natalia , Bartosik-Psujek Halina , Kalinowska Alicja , Kułakowska Alina , Mirowska-Guzel Dagmara , Rejdak Konrad , Stasiołek Mariusz , Stępień Adam , Adamczyk-Sowa Monika
Published: March 2024

Kladrybina w tabletkach jest dostępna w Polsce do leczenia rzutowo-remisyjnej postaci stwardnienia rozsianego, zarówno u pacjentów wcześniej nieleczonych, jak i po wcześniejszym leczeniu oraz w szybko rozwijającej się, ciężkiej postaci choroby. W niniejszym opracowaniu grono polskich ekspertów na podstawie własnych doświadczeń klinicznych oraz danych literaturowych sformułowało praktyczne zalecenia dla lekarzy neurologów dotyczące stosowania kladrybiny w tabletkach. Poruszono kwestie profilu pacjenta, u którego należy zastosować lek, czynników predykcyjnych skuteczności leczenia, zmiany leczenia z innych terapii modyfikujących przebieg choroby na kladrybinę i z kladrybiny, profilu bezpieczeństwa leku, diagnostyki przed rozpoczęciem terapii, monitorowania leczenia, skuteczności szczepień w okresie leczenia, interakcji kladrybiny z innymi preparatami oraz planowania ciąży.
Komentarz w sprawie aktualnych możliwości wyboru terapii modyfikujących przebieg choroby
Authors: Mirowska-Guzel Dagmara , Kułakowska Alina , Brola Waldemar , Stasiołek Mariusz , Wawrzyniak Sławomir , Zakrzewska-Pniewska Beata , Kurkowska-Jastrzębska Iwona , Nojszewska Monika , Podlecka-Piętowska Aleksandra , Rościszewska-Żukowska Iwona , Adamczyk-Sowa Monika
Published: March 2024

Brak
Pacjentka z nowo zdiagnozowaną rzutowo-remisyjną postacią stwardnienia rozsianego, u której zastosowano leczenie fumaranem dimetylu de novo – opis przypadku
Authors: Kubicka-Bączyk Katarzyna , Adamczyk-Sowa Monika
Published: March 2024

Obecnie w leczeniu rzutowo-remisyjnej postaci stwardnienia rozsianego dysponujemy kilkunastoma lekami wpływającymi na przebieg choroby o różnej skuteczności i profilu bezpieczeństwa. Optymalne dobranie leku i rozpoczęcie takiej terapii tuż po rozpoznaniu choroby daje szansę na zatrzymanie jej progresji i utrzymania niskiego odsetka rzutów. Celem pracy jest opis przypadku pacjentki z rzutowo-remisyjną postacią stwardnienia rozsianego, u której zastosowano leczenie fumaranem dimetylu de novo.
Ultrasound-Assisted Extraction of Okra Mucilage: Rheological Properties of its Aqueous Solutions
Authors: Akcan Tolga , Öncü Glaue Şelale
Published: March 2024

Using chemical and physicochemical techniques, we extracted the mucilaginous component of okra (Abelmoschus esculentus L.) by the ultrasound-assisted extraction method, then evaluated the resulting polysaccharide extract's rheological properties. Our investigation encompassed examining the flow behavior of polysaccharides extracted under different okra to distilled water ratios (1:10 and 1:30) and various polysaccharide concentrations (1, 2, 3 and 4%, w/v) over a temperature range of 10°C to 80°C. Employing the power law model, we derived parameters and found that okra polysaccharides displayed non-Newtonian pseudoplastic flow characteristics. The flow behavior index ranged from 0.234 to 0.947, with the consistency coefficient ranging from 4.37 to 244.50 mPa.s. Increasing temperature resulted in a decrease in both the consistency coefficient (K) and flow behavior index (n), while concentration elevation led to higher consistency coefficient values. However, the flow behavior index did not exhibit consistent trends with concentration variations. Three statistical parameters; correlation coefficient (R2), root mean square error (RMSE) and chi-square (χ2) were used to evaluate the fit of the power law model to the experimental data. Our study further explored temperature’s impact on the apparent viscosities of okra polysaccharide samples and modeled the influence of temperature on the consistency index using the Arrhenius equation. Samples with solid-to-solvent ratios of 1:10 and 1:30 showed increasing activation energy with concentration rise, with the highest value recorded at 275.84 kJ/mol for the 1:10 ratio sample with a 4% concentration. In SEM images, okra polymers exhibit irregular, wavy, rough textured surface, and amorphous appearance. These findings hold promise for optimizing ultrasound extraction protocols and enhancing the industrial utilization of mucilages through their rheological properties.
Are changes in olanzapine-induced liver enzyme levels associated with GSTT1, GSTM1, GSTP1, and OGG1 gene polymorphisms?
Authors: Elkama Aylin , İlik Nazlıcan , Ak Mehmet , Karahalil Bensu
Published: March 2024

Olanzapine treatment sometimes produces transient liver biochemistry abnormalities, and such drug-induced liver injuries are mainly monitored by measuring blood levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), whereas alpha-glutathione-S-transferase (α-GST) is not routinely measured in clinics, even though it can serve as an earlier and more specific biomarker of liver damage. Susceptibility to drug-induced liver injury can much depend on the gene polymorphisms regulating the activity of DNA detoxification and repair enzymes. The aim of this study was to evaluate which of the three liver enzymes – α-GST, ALT, and AST – is the most sensitive biomarker of olanzapine-induced liver injury and how their blood levels are affected by the GSTT1, GSTM1, GSTP1, and OGG1 gene polymorphisms in 30 olanzapine-treated patients. Contrary to our hypothesis, the increase in serum α-GST levels was not significantly greater than that of the transaminases. ALT turned out to be an earlier biomarker of liver injury than the other two enzymes. No significant association was found between gene polymorphisms and liver enzyme levels, save for GSTP1 Ile/Val + Val/Val and ALT, which points to this genotype as a risk factor for drug-induced liver injury. Future studies might help to identify the underlying mechanisms of transient liver enzyme increase associated with this genotype.
Comparative analysis of organophosphorus versus carbamate pesticide poisoning: a case study
Authors: Xia Jia-ding , Wang Hui , Hua Li-wei , Xu Min , Zheng Xin , Zhang Kun
Published: March 2024

Organophosphorus poisoning is a critical condition that can cause central nervous system depression, respiratory failure, and death early on. As its clinical manifestations closely resemble those of carbamate pesticide poisoning, the aim of this case study is to present a case of misdiagnosis, initially identifying carbofuran poisoning as organophosphate in a patient suspect of a heatstroke. We also present a case of intentional self-poisoning with organophosphate dichlorvos to underline the likelihood of pesticide poisoning in patients exhibiting acute cholinergic symptoms when the ingested substance is not known. In such cases, empirical treatment with atropine and oxime can be started pending timely differential diagnosis to adjust treatment as necessary.
Frequency of regular walking among Croatian adults
Authors: Krtalić Slaven , Križan Helena , Milanović Sanja Musić
Published: March 2024

The aim of this study was to determine the share of Croatian adults who walk 210 min or more a week and to explore the relationship between regular walking and demographic factors, health-related behaviours, and chronic non-communicable diseases/conditions. To this end, we used the EHIS-PAQ questionnaire and collected self-reported data on minutes spent walking during a typical week from a total of 3,496 respondents. The data were additionally analysed by gender, age, education, residence (urban/rural), counties and regions, smoking, other types of physical activity, and diseases/chronic conditions. The results show that, overall, 40.9 % of the adult Croatian population walks 210 or more minutes a week, with the largest share found among those from the Lika-Senj County (76.8 %), those who spend 300 min or more weekly on health-enhancing (non-work-related) aerobic physical activity (57.6 %), those who reported having diabetes (49.3 %), and those aged 65–74 years (44.7 %). Despite its limitations, our study gives a valuable insight into the frequency and factors determining healthy walking habits in a representative sample of Croatian adults and provides grounds for further research.
Rings with centrally-extended Jordan epimorphisms
Authors: Gouda Aziza , Nabiel Hesham
Published: March 2024

The aim of this article is to introduce the concept of centrally-extended Jordan epimorphisms and proving that if R is a non-commutative prime ring (∗-ring) of characteristic not two, and G is a CE-Jordan epimorphism such that [G(x), x] ∈ Z(R) ([G(x), x
∗] ∈ Z(R)) for all x ∈ R, then R is an order in a central simple algebra of dimension at most 4 over its center or there is an element λ in the extended centroid of R such that G(x) = λx (G(x) = λx
∗) for all x ∈ R.
Food Safety: A Developing Country Perspective
Authors: Togan Sübidey
Published: March 2024

Developing countries, trying to achieve an acceptable level of food safety at the least possible cost (efficiency objective) and facilitation of market access to the large and lucrative developed country food markets (market access objective), could follow the multilateral, regional, unilateral or the independent approach. The paper studying the pros and cons of these approaches aims to determine the most appropriate food safety reform package. It shows that the best approach is the unilateral. Under this approach the achievement of efficiency objective requires the adoption and implementation of the multilateral approach. The achievement of market access objective requires the adoption and implementation of the regulatory regime of the developed country whose markets the developing country is intending to penetrate. Instead, the paper proposes that the developing country adopts and implements the developed countries‘ regulatory regime only in agricultural sub-sectors with highest comparative advantage scores, and that in all other agricultural sub-sectors the country should adopt and implement the regulatory regime as developed by multilateral approach. Since the tasks associated with designing and implementing the food safety policy reform are challenging, the paper advocates that this task should be left to a new institution, the ‘Food Safety Council‘, which needs to be formed as an autonomous public institution with sufficient financial and technical resources.
Perkembangan gonad, fekunditas dan diameter telur Hemisilurus heterorhynchus, Bleeker 1854 di sungai paparan banjir, Desa Mentulik, Kampar Kiri, Riau
Authors: Elvyra Roza , Fitri Febrian Lailatul , Yusfiati Yusfiati , Khairijon Khairijon , Wardani Imelda
Published: March 2024

Floodplain river is one of the freshwatercharacteristics of Riau Province. Selais humped fish (Hemisilurus heterorhynchus) is a demersal freshwater fish. and usually lives in tropical areas with rivers that are flood-prone. H. heterorhynchus is often caught regardless of size so that fish that are immature or have immature gonads are also caught. If this condition continues, it is likely that H. heterorhynchus will experience a population decline. Therefore it is necessary to conduct research on the reproductive biology of H. heterorhynchus to find out, gonadal development, gonado somaticindex (GSI), egg diameter, fecundity, the relationship between fecundity and body length and weight, spawning season and fish spawning patterns so that it can be used as a basis for conservation and cultivation of H. heterorhynchus. This research was conducted from October to March on the Kampar Kiri river. Gonad mature male and female fish were mostly found at the beginning of the rainy season in October and November. The highest male GSI was obtained in October (0.24%) and female in November (2.80%). Fecundity of H. heterorhynchus ranged from 6444-20654 eggs. The spawning pattern of H. heterorhynchus fish is once a year (total spawner).