bluuebunny/crossref_metadata_2025 huggingface dataset:
Pandemia no capitalismo dependente
Authors: Nogueira Kleiton Wagner Alves da Silva , Santos Nivalter Aires dos
Published: June 2022

Objetivamos investigar os limites do enfrentamento da pandemia da COVID-19 no Brasil, nos seus 180 primeiros dias. Em termos metodológicos propomos um levantamento bibliográfico, a fim de encontrar lacunas nas abordagens no campo das ciências sociais, e propor uma análise de discurso, em um sentido marxista. Como resultado, indicamos dois conjuntos de problemas: um orgânico que tem relação com a condição de país de capitalismo dependente que engendra uma forma de dominação autocrática que influencia diretamente na saúde pública; o outro tem relação com o governo Bolsonaro e sua inércia ao tratar a crise sanitária. Também constatamos o quanto a pandemia desenvolve-se de maneira desigual, atingindo majoritariamente os mais pobres e os negros/pardos, o que evidencia o concreto caráter de classe da pandemia no Brasil. Por fim, indicamos a crítica aos limites das abordagens que defendem a volta do Estado keynesiano como solução diante da crise do neoliberalismo que o coronavírus escancara.
Social comparisons: A potential mechanism linking problematic social media use with depression
Authors: Samra Adele , Warburton Wayne A. , Collins Andrew M.
Published: June 2022

Background and aims

The majority of Australians are regular users of social media, especially young adults. Of concern, is that a minority of people appear to use social media in an addictive or problematic way which is associated with negative psychological outcomes such as depression. Social comparisons, where users compare themselves to others on social media, have also been linked with depression. Therefore, the key aim of the study was to determine whether social comparisons mediate the relationship between Problematic Social Media Use (PSMU) and depression.

Method

In a two-part study 144 participants (65 females) answered a series of self-report questions assessing factors relating to PSMU and then came into the lab to view a series of social media images, (pre-tested to be upward or downward comparisons).

Results

Females used social media more problematically, liked more upward than downward comparison images and compared themselves more negatively to others on social media than did males. Higher PSMU scores were associated with depression and low self-esteem and comparing oneself more negatively to others on social media. Finally, focusing on upward comparisons and a tendency to make negative comparisons to others on social media partially mediated the association between PSMU and depression.

Discussion and conclusions

Social comparisons may function as a mechanism linking PSMU with negative psychological outcomes. Clinical interventions for individuals with PSMU which reduce the focus on upward social comparisons may also reduce negative psychological outcomes such as depression.
Phytochemistry Screening and Antioxidant Activities of Extract Pomegranate, Grape, Fig, and Olive in the Various Solvent
Authors: Savitri Evika Sandi , Holil Kholifah , Resmisari Ruri Siti
Published: June 2022

The active compounds of grape, pomegranate, olive, and fig have anthocyanins that potential as antioxidant are flavonoids. Flavonoids have potential as antioxidant  to prevent and therapy various oxidative stress and related diseases. This study aimed to examine the antioxidant activity of a combination of pomegranate, grape, fig, and olive extracts using the DPPH (diphenyl-2-picrylhydrazyl) method.  The maceration method used was maceration of dry Simplicia with methanol 95% solvent, fresh maceration with 95% methanol and dry Simplicia with 95% ethanol solvent. The results of the phytochemistry test showed several compounds found in the extract combination pomegranate, grapes, fig, and olives such as polyphenol, flavonoid, tannin, steroid/triterpenoid. The result of the antioxidant test showed the fresh maceration 95% methanol showed higher results with the IC50 of 25.22 with a potent antioxidant activity category.
Terapi Pemaafan untuk Menurunkan Tingkat Kecemasan Remaja Korban Kekerasan
Authors: Oktaviana Sherli Kurnia
Published: June 2022

The purpose of this study is to examine the effect of forgiveness therapy on decreasing anxiety level of the teenager victim of abuse. The research design used quasi-experimental pretest-posttest control group design. The participants were 22 teenagers aged 15-18 years old that were grouped into experimental and control groups. The instrument used Depression Anxiety Stress Scale by Lovibond and Lovibond (1995) and adapted into Indonesian by Damanik (2014). The data analysis used two independent sample test with Mann Whitney test. The analysis results of pretest and posttest show there is difference of anxiety level between experimental and control groups. The given therapy has a significant effect size of 84.6%.
Tensions and potentials of translanguaging in online spaces
Authors: Alarcón Jeannette D , He Ye , Lachance Joan , Schissel Jamie L , Zoch Melody
Published: June 2022

While dual language bilingual education (DLBE) programmes in the United States aim at cultivating pedagogical practices that support bilingualism and biliteracy development, they often idealise instructional models that separate languages within instruction and create educational spaces that privilege monolingual English-language proficiency standards. Scholars have called on schools to focus on the learning needs of language-minoritised learners through pedagogies that build upon the bilingual resources from language-minoritised learners and educators. One approach is adopting translanguaging pedagogies that promote flexible, hybrid, fluid languaging practices and advance social justice agendas in classrooms, ensuring that all students are educated deeply and justly. With the transition to and expansion of online teacher education programmes, it is critical to explore how teacher educators support teachers’ beliefs regarding translanguaging in online spaces. This self-study aimed to investigate our efforts as teacher educators to include translanguaging pedagogies as both a way to model practices and a conceptual framework for supporting in-service teachers to understand languages and language learning at a deeper level by exploring the guiding question: How has translanguaging (planned and unplanned) been part of online DLBE teacher education learning spaces? Using a narrative inquiry analysis based on teacher educators’ individual journals and critical friend group discussions, we explored both the tensions and potentials in online teaching and teacher education spaces based on our experiences.
‘Keeping home languages out of the classroom’
Authors: Zhang-Wu Qianqian
Published: June 2022

Despite the growing cultural and linguistic diversity, monolingual ideologies are still rampant in American higher education. As an effort to decentre English-only, translingualism is gaining momentum in US college composition studies. Yet, existing research on translingual writing at the tertiary level remains largely conceptual and focused on in-person teaching contexts. Focusing on an argumentative essay unit in an asynchronous online writing class designed specifically for first-year multilingual international students, this exploratory qualitative study seeks to answer: (1) How did the participants perceive home language usage in American higher education? (2) How, if at all, did they put translingual writing into practice in the online writing class? Drawing upon analysis of students’ online discussion board posting, responding and their argumentative essays, the study indicates that most multilingual international students were predisposed with an English-superiority fallacy and argued that home languages should be kept out of the college classrooms. While most of the class chose to resort to English in their academic writing, several students enacted translingualism and code-meshed with their home languages to serve different purposes. This study sheds light on the complexity and dynamics of multilingual students’ translingual written practices online and points out directions for future research.
Translanguaging as decolonial praxis
Authors: Odugu Desmond I
Published: June 2022

Epistemic ruptures in normative conceptualisations of language bring into sharper focus the absurdities of education in entrenched linguistic and disciplinary regimentations. At a time when neoliberal forces push educational processes farther from traditional disciplinary arrangements and towards nuclear marketisation of knowledge and processes of knowledge production, the convergence of epidemiological and social crises occasioned by the Covid-19 pandemic forces educators to recalibrate pedagogical structures that have guided schooling processes for decades. Drawing insights from two emergency remote courses, this article examines the pedagogical and conceptual thrusts of translanguaging in US higher education. It outlines specific ways in which the institutional formations of knowledge – its (re)production, structuration and transaction – undercut the logic and political potency of translanguaging. Specifically, it locates translanguaging within a broader constructionist linguistic ontologism, which now provides conceptual tools for readjusting the epistemic aperture through which new cultural attitudes to knowledge – and to education – can materialise institutional transformations towards what Lewis Gordon (2021) calls ‘teleological suspension’. While public consciousness remains inured to the presumed cultural neutrality and political benignity of schooling as pervasive social practice, this study contends that it is precisely in the ubiquitous subtleties of institutional formations that the politics of official knowledge exercises most effectively its technologies of cultural control, and of exploitation. As such, the epistemic shifts which translanguaging and similar expressions of constructionist linguistic ontology invite extend far beyond language policy changes and point to radical social transformations.
Pedagogical translanguaging in Content and Language Integrated Learning
Authors: Cenoz Jasone , Gorter Durk
Published: June 2022

Translanguaging has its origin in Welsh bilingual education and it refers to a pedagogical practice which alternates the languages of the input and the output in the same lesson. Pedagogical translanguaging is closely related to the original approach to translanguaging but goes beyond the practice of language alternation. Pedagogical translanguaging is learner-centred and endorses the development of all the languages used by learners. It fosters the development of metalinguistic awareness and goes against the tradition of language separation in school settings by softening boundaries between languages when learning languages and content. This article discusses the challenge of using pedagogical translanguaging in Content and Language Integrated Learning (CLIL). CLIL programmes are more demanding than regular programmes because content is taught through the medium of a second or additional language. The language used in content subjects is in many cases substantially different and more complex than the language used in language classes. Pedagogical translanguaging can support students in CLIL programmes when working with new concepts and academic uses of the language, and can be adapted to synchronous and asynchronous online learning.
Improved method for the obtaining DTTA-appended 2,2’-bipyridine ligands for lanthanide cations
Authors: Kopchuk Dmitry S. , Krinochkin Alexey P. , Valieva Мaria I. , Starnovskaya Еkaterina S. , Shtaitz Yaroslav K. , Rybakova Svetlana S. , Ladin Evgeny D. , Kudryashova Ekaterina A. , Sharafieva Elvira R. , Chupakhin Оleg N.
Published: June 2022

The composition of the reaction mixture after DTTA tert-butyl ester alkylation with 6'-halomethyl-5-phenyl-2,2'-bipyridines was studied. In addition to the target product, DTTA-appended 2,2’-bipyridine, the corresponding 6'-hydroxymethyl-substituted 2,2’-bipyridine and (5'-phenyl-[2,2'-bipyridin]-6-yl)methyl formate were isolated as by-products in some cases. Finally, an improved procedure for the DTTA tert-butyl ester alkylation with 6'-halomethyl-5-phenyl-2,2'-bipyridines by using Finkelstein reaction was developed.
Influence of the micromycete Fusarium culmorum and its antagonists on the state of the antioxidant system of Melissa officinalis L.
Authors: Skugoreva Svetlana , Gushchina Polina , Sharipova Yana , Darovskikh Larisa
Published: June 2022

In recent years, the popularity of herbal medicine has increased. Lemon balm (Melissa officinalis L.) is a perennial essential oil herb that has been used as a medicinal plant for more than 2 thousand years. It is known that the productivity of plants is directly related to their resistance to phytopathogens, in particular, micromycetes of the genus Fusarium. One of the main mechanisms of plant damage by phytopathogens is oxidative stress. Micromycetes of the genus Trichoderma and soil cyanobacteria (CB) occupy an important place among the natural antagonists of fungi of the genus Fusarium. The aim of the work was to study the state of the antioxidant system of Melissa officinalis L. plants when grown on substrates contaminated with the micromycete Fusarium culmorum and its antagonists – the cyanobacterium Fischerella muscicola and the micromycete Trichodеrma viride. It was found that the presence of the pathogenic micromycete F. culmorum in the soils for growing lemon balm for two months has a stressful effect on lemon balm plants: the intensity of lipid peroxidation, the content of phenolic compounds and the amount of antioxidants in the in plant leaves were significantly higher than in the control. At the same time, at elevated temperatures, the content of phenolic compounds increased, which may be due to increased metabolism and the level of oxidative stress. The introduction of microorganisms-antagonists F. muscicole and T. viride into the soil makes it possible to activate the work of the antioxidant system of plants and reduce the effects of oxidative stress almost to the level of control. The studied antagonists can be recommended as promising for the development of biological products on their basis in order to protect medicinal plants from fusarium diseases.
Coronary Artery Calcification Score and the Progression of Chronic Kidney Disease
Authors: Yun Hae-Ryong , Joo Young Su , Kim Hyung Woo , Park Jung Tak , Chang Tae Ik , Son Nak-Hoon , Yoo Tae-Hyun , Kang Shin-Wook , Sung Suah , Lee Kyu-Beck , Lee Joongyub , Oh Kook-Hwan , Han Seung Hyeok
Published: June 2022

Significant Statement

Coronary artery calcification (CAC) is an independent risk factor of cardiovascular disease (CVD) regardless of CKD status, and the CAC score (CACS) may have clinical implications beyond an increased CVD risk. In a prospective cohort study from 1936 patients with CKD in South Korea, higher CACS (1–100 AU and >100 AU) was associated with an increased risk of CKD progression (1.29-fold and 1.42-fold, respectively) compared with a CACS of 0. This association was consistent even after adjustment of nonfatal cardiovascular events being treated as a time-varying covariate. Moreover, the slope of eGFR decline was significantly greater in patients with higher CACS. These findings suggest that CACS may represent potential risk of CKD progression and high odds for adverse CVD.

Background

An elevated coronary artery calcification score (CACS) is associated with increased cardiovascular disease risk in patients with CKD. However, the relationship between CACS and CKD progression has not been elucidated.

Methods

We studied 1936 participants with CKD (stages G1–G5 without kidney replacement therapy) enrolled in the KoreaN Cohort Study for Outcome in Patients With CKD. The main predictor was Agatston CACS categories at baseline (0 AU, 1–100 AU, and >100 AU). The primary outcome was CKD progression, defined as a ≥50% decline in eGFR or the onset of kidney failure with replacement therapy.

Results

During 8130 person-years of follow-up, the primary outcome occurred in 584 (30.2%) patients. In the adjusted cause-specific hazard model, CACS of 1–100 AU (hazard ratio [HR], 1.29; 95% confidence interval [CI], 1.04 to 1.61) and CACS >100 AU (HR, 1.42; 95% CI, 1.10 to 1.82) were associated with a significantly higher risk of the primary outcome. The HR associated with per 1-SD log of CACS was 1.13 (95% CI, 1.03 to 1.24). When nonfatal cardiovascular events were treated as a time-varying covariate, CACS of 1–100 AU (HR, 1.31; 95% CI, 1.07 to 1.60) and CACS >100 AU (HR, 1.46; 95% CI, 1.16 to 1.85) were also associated with a higher risk of CKD progression. The association was stronger in older patients, in those with type 2 diabetes, and in those not using antiplatelet drugs. Furthermore, patients with higher CACS had a significantly larger eGFR decline rate.

Conclusion

Our findings suggest that a high CACS is associated with significantly increased risk of adverse kidney outcomes and CKD progression.
Influence of preparation regimes and composition on structure, phase state and electric properties of nanogranular (FeCoZr)x(PZT)100-x (30 ≤ x ≤ 85 at.%) films
Authors: Fedotova J. A.
Published: June 2022

Granular films containing Fe50Co50Zr10 alloy nanoparticles inside the ferroelectric matrix Pb0.81Sr0.04(Na0.5Bi0.5)0.15(Zr0.575Ti0.425)O3 (PZT) are characterized by a complex of functional magnetic and electrical characteristics that can be effectively controlled by an external electric or magnetic field. The formation of the necessary granular structure in the case of a PZT matrix is possible only during synthesis in an oxygen-containing atmosphere, leading to significant oxidation of metal nanoparticles. In this regard, an urgent task is to study the degree of oxidation of metal nanoparticles depending on the synthesis conditions, as well as the influence of the forming phases on the electrical properties of films.The relationship of the phase composition and electrical characteristics of granular films (FeCoZr)x(PZT)100-x (30 ≤ x ≤ 85, at.%) obtained in an oxygen-containing atmosphere at a pressure of PO in the range (2.4—5.0) ⋅ 10-3 Pa was studied by X-ray diffraction analysis, EXAFS spectroscopy (Extended X-ray Absorption Fine Structure) and four-probe electrical resistivity measurements.A comparative complex analysis of the structural-phase composition and local atomic order in films (FeCoZr)x(PZT)100-x for the first time showed the fundamental influence of oxygen pressure during synthesis on the oxidation of nanoparticles and their phase composition. It is shown that in the case of oxygen pressure up to the values of PO = 3.2 ⋅ 10-3 Pa, a transition from nanoparticles of complex Fe(Co,Zr) oxides occurs with increasing x to the superposition of complex oxides and ferromagnetic nanoparticles α-FeCo(Zr,O) (or their agglomerations). At a higher oxygen pressure PO = 5.0 ⋅ 10-3 Pa, complete oxidation of nanoparticles is observed with the formation of a complex oxide (FexCo1-x)1-δO with a wustite structure.The observed structural-phase composition allows us to explain the measured temperature dependences of the electrical resistance of granular films, characterized by a negative temperature coefficient of electrical resistance (TKR) in the entire range of film compositions at high oxygen pressure (PO = 5.0 ⋅ 10-3 Pa), and the transition to positive TKR at lower oxygen pressure (PO = 3.2 ⋅ 10-3 Pa) in the synthesis atmosphere and the value x ≤ 69 at.% in films. The transition from negative to positive TKR, indicating the presence of a metallic contribution to conductivity, is fully correlated with the detection by XRD and EXAFS methods of non-oxidized ferromagnetic nanoparticles α-FeCo(Zr,O) or their agglomerations.
Dielectric and piezoelectric properties of PLZT x/40/60 (x = 5; 12) ceramics
Authors: Shcheglova A. I. , Kislova I. L. , Ilina T. S. , Kiselev D. A. , Barabanova E. V. , Ivanova A. I.
Published: June 2022

The paper presents the results of studies of the structure, piezoelectric and dielectric properties of lead zirconate-titanate ceramics modified with lanthanum of various concentrations (PLZT). It was found that with an increase in the La content, the grain size and the average domain size increase. The PLZT 12/40/60 samples contain both labyrinth-like and periodic domains, as well as different lateral sizes from several hundred nanometers to 3 microns in diameter. It was found that the piezoelectric response signal increases with increasing domain sizes in samples with a high lanthanum content. The fact of the existence of areas on surface of PLZT x/40/60 ceramics having an internal displacement field is established, as evidenced by the asymmetry of the remnant piezoelectric hysteresis loops along the voltage axis. In the samples PLZT 5/40/60 and PLZT 12/40/60, a significant dispersion of the permittivity ε(f) and a maximum of the tangent of the dielectric loss angle were observed in the frequency range from 105 to 106 Hz. This is due to the presence of ionic relaxation polarization, as is the case in ionic dielectrics. It is established that the value of the dielectric constant increases markedly with increasing La, which confirms the occurrence of a rigid unipolar state in the PLZT 12/40/60 ceramic grains. In the samples under study, an increase in the tangent of the dielectric loss angle is observed at low frequencies of the measuring field, which is associated with the contribution of conductivity to tg δ. The dependences of the dielectric loss factor ε” on the dielectric permittivity ε’are constructed. They have the form of Cole-Cole diagrams, which indicates the presence of a relaxation time spectrum, while it was found that the spectrum width in PLZT 5/40/60 samples is about two times less than in PLZT 12/40/60 samples.
Analysis of hydrodynamics in the synthesis of crystals from aqueous salt solutions
Authors: Prostomolotov A. I. , Verezub N. A.
Published: June 2022

The flow structure and mass transfer in crystallizers determine the level of salt supersaturation of the solution near the crystallization surface. However, experimental determination of such supersaturation is difficult. Therefore, it is important to develop adequate numerical models for studying the flow and mass transfer in real molds. Simulation tools were used to study the effectiveness of fundamentally new experimental schemes of the process for the stable growth of KDP crystals.
Machining technology, digital modelling and shape control device for large parts
Authors:   Limited Liability Company «Promagro», Shebekino, Russian Federation, Timofeev Sergey , Grinek Anna ,   Admiral Ushakov State Maritime University, Novorossiysk, Russian Federation, Hurtasenko Andrey ,   Belgorod State Technological University named after V.G. Shukhov, Russian Federation, Boychuk Igor ,   Admiral Ushakov State Maritime University, Novorossiysk, Russian Federation
Published: June 2022

Introduction. The development of a method for controlling the accuracy parameters of large axisymmetric bodies is an urgent task that is being solved by specialists from various industries. Application for adjustment and correction of machining based on the measurement of surface shape parameters directly during machining is shown. Purpose of work is to improve mobile processing technologies using special measuring devices and processing module. For this, the problems of development and analysis of mathematical models that describe the process of basing and machining of a riding ring as a cylindrical object with a non-stationary axis of rotation is solved. A study of the methodology is carried out, control schemes are designed, and equipment for processing mobile devices is developed. The methods of research are the analysis of the developed mathematical models, taking into account the assignment of effective technological modes. Three-dimensional and simulation modeling of processing, hardware-software implementation of proposed solutions, and statistical processing of measurement results are carried out. Results and discussion. The algorithm and methodology are tested with a three-dimensional simulation model. The presented methodology for measuring and calculating the allowance for mechanical restoration can significantly reduce machining time compared to active form control and compared to the traditional method of assigning an allowance for machining. The measurement and adjustment of the allowance based on the measurement data is not carried out after each measurement, but only in the case of transition to finishing transitions or for accuracy control. It is determined that by providing a single technological base for each individual technological transition within the framework of the mobile technology of machining of the rolling surface of the riding rings of technological drums, the accuracy and speed of processing increase. An original design of the device for monitoring parameters is developed; an experimental assembly and a laboratory model of the riding ring are made.
Food security and safety during Novel coronavirus (COVID-19)
Authors: Wabi Bajo Nagessa , Francois Lusamaki Mukunda , Gemechu Geleta Abdi
Published: June 2022

This review paper was prepared by reviewing and summarizing several findings including research articles, FAO, and WHO databases concerning the pandemic and related issues. The security and safety status of foods during the pandemic outbreak and the possible solutions to food-related problems were also reviewed. The COVID-19 pandemic is currently not only affecting health but also the security of foods and nutrition. The effect of the Covid-19 on the entire food along the value chains was reviewed in this paper. The Coronavirus has been disturbing the health of world populations and food security. It is critically affecting the food processing business in various ways. The mitigating measures taken to contain the virus and decrease transmission to society are directly and indirectly affecting food security and safety. The overall food system is being disturbed by movement restrictions, closure of borders, and quarantine in turn resulting in low availability of food and an increase in the price of food products. The effect of the pandemic on food security can be estimated based on the impacts the previous pandemic Ebola made on the DRC and Liberia in 2014. The effects of the pandemic on the food production system and availability are similar. The mitigating measures suggested like movement restrictions, social distancing, and border closing and quarantine to protect the people from the COVID-19 are affecting global food security at large. Keeping the movement of foods along the value chain is crucial to creating and maintaining the confidence of consumers in the availability and safety of foods. Both security and the safety of foods are important things to be considered throughout the pandemic era. The important issue is that the low access to food and increase in price is challenging because; the pandemic affects labour for production at the farm, food processing personnel, marketing, and all the supply chains from production up to fork.
[RETRACTED] Willie Nelson CBD Gummies Reviews, Price, Side effects 2022 v1
Authors: not provided willienelsongummiesreview
Published: June 2022

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Synchronized spinal nerve and dorsal root ganglia stimulation v1
Authors: Chen Longtu
Published: June 2022

Assessing the instantaneous effect of dorsal root ganglia (DRG) stimulation on the transmission of electrically evoked action potentials from the spinal nerve via the ex vivo preparation with mouse L6 spinal nerve (SN), DRG, and dorsal root (DR) in continuity, i.e., the SN-DRG-DR preparation. Synchronized spinal nerve and DRG stimulation reveal a progressive increase in conduction delay by DRG stimulation, suggesting an activity-dependent slowing in blocked fibers. Midrange frequencies (50-500 Hz) are more efficient at blocking transmission than lower or higher frequencies.
[RETRACTED] https://www.facebook.com/Oprah-Winfrey-Weight-Loss-Gummies-107872055271296 v1
Authors: not provided bdeef
Published: June 2022

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Authors: not provided jamesbrooks
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[RETRACTED] Via Keto Gummies Reviews – Is Via Keto Legit for Weight Loss (SCAM)? v1
Authors: Keto Gummies Via
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[RETRACTED] Mitochondrial Quality and Membrane Potential Detection v1
Authors: not provided mitsjoecohen
Published: June 2022

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A large number of studies have shown that mitochondria are closely related to apoptosis, in which the decrease of mitochondrial transmembrane potential (MMP) is considered one of the earliest events in the cascade of apoptosis. It occurs before the appearance of the characteristics of nuclear apoptosis (chromatin condensation, DNA fragmentation). Once the mitochondrial transmembrane potential collapses, apoptosis is irreversible. JC-1 has two states of monomer and polymer, and their emission spectra are different. In normal cells, the membrane potential of mitochondria is higher, and JC-1 aggregates in the matrix of mitochondria to form polymers, which can produce red fluorescence. In the early stage of apoptosis, the mitochondrial membrane potential decreases and JC-1 could not accumulate in the mitochondrial matrix. At this time, JC-1 is a monomer and could produce green fluorescence. The decrease of cell membrane potential can be detected by the transformation of JC-1 from red fluorescence to green fluorescence, and the change of JC-1 fluorescence color can be used as an early detection index of apoptosis. The relative ratio of red and green fluorescence is often used to measure the proportion of mitochondrial depolarization.
[RETRACTED] Keto X3 Reviews [Updated 2022]-How To Know It Is Worth Your Money? v1
Authors: not provided keto-x-reviews
Published: June 2022

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Yeast cells live fluorescence imaging v1
Authors: Wilfling Florian
Published: June 2022

Protocol for sample preparation and live fluorescence imaging of yeast cells.
[RETRACTED] Uly Keto CBD Gummies Reviews! v1
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REHABILITATION PROCEDURES AS A TOOL FOR OVERCOMING A CRISIS SITUATION IN MODERN ECONOMIC CONDITIONS
Authors: Vdovkina D. A.
Published: June 2022

This article discusses the rehabilitation bankruptcy procedures used in Russia today. The greatest attention is paid to the procedures of financial recovery and external management, as the most common and frequently used. The disadvantages and advantages of each of the procedures are noted, as well as the reporting of the FSB on the use of financial recovery and external management in 2021 is analyzed in detail. There is a clear inconsistency of these procedures in our country. The author deduces a number of possible reasons for the unpopularity of rehabilitation procedures. However, there is an attempt by the state in 2021 to amend this provision by introducing a draft law on the introduction of amendments to the bankruptcy law, which directly related to rehabilitation procedures. The disadvantages and advantages of the bill are highlighted. The author also emphasizes that in 2022, due to the difficult economic and political situation, it became possible to give the external management procedure a “second wind”.
Role of glutamate receptor complex in the organism. Ligands of NMDA receptors in neurodegenerative processes – a modern state of the problem
Authors: Dergachev Vladimir D. , Yakovleva Ekaterina E. , Bychkov Eugenii R. , Piotrovskiy Levon B. , Shabanov Petr D.
Published: June 2022

(S)-glutamic acid (glutamate) is the main excitatory mediator in the central nervous system, responsible for regulating of many physiological functions. Dysfunction of the glutamatergic system characterizes of many pathological conditions in neurology and psychiatry, and the aberrant function of glutamate receptors plays a key role in the development of neurodegenerative processes. Glutamate is crucial for many aspects of normal brain function, including memory, learning, and motor planning. In addition, glutamate is involved in the regulation of the peripheral nervous and endocrine systems. Glutamate receptors are critically important molecules necessary for the physiological functioning of the brain: they modulate neurotransmission and regulate the strength of excitatory and inhibitory transmission in the nervous system. In this regard, the use of drugs that affect glutamatergic transmission has an impact on the most important processes of neuronal transmission. The research and development of pharmacological agents involved in the processes of glutamate transmission is a relevant task of modern neuropsychopharmacology and has a purpose to improve the effectiveness and safety of available glutamatergic molecules.
Evaluation of the bioavailability of 1H-imidazole-4,5-dicarboxylic acid derivatives using the calculated and experimental lipophilicity index of the molecule logP
Authors: Iljin Victor V. , Litasova Elena V. , Kvasov Maksim S. , Brusina Mariia A. , Piotrovskiy Levon B.
Published: June 2022

BACKGROUND: It is important to know the ability of a substance to penetrate the cell membrane to assess the bioavailability of drugs. The distribution of matter between the organic phase and water can be used as a model of the distribution between the membrane and extracellular fluid, and can be expressed by a partion coefficient, called logP.
AIM: The aim of this work was to determine the logP of 1H-imidazole-4,5-dicarboxylic acid (IDC) derivatives in various media and compare the values with theoretical ones.
RESULTS: As a result of the work, the distribution coefficients of the IDC derivatives were determined from the optical density data for a fixed wavelength of 250 nm (without a buffer). The distribution coefficients of the IDC derivatives over the maxima of the UV spectra (in the buffer) were determined. A comparison of theoretical and experimental values of the distribution coefficients of some IDC derivatives is carried out.
CONCLUSION: Thus, it has been shown that for a more accurate assessment of the bioavailability of drugs, it is not enough to rely only on the calculated logP index, it is necessary to conduct an experimental test, or introduce some correction factors to recalculate the theoretical logP index, in each specific class of compounds.
Bingöl İlinde Halk Elinde Yetiştirilen Akkaraman ırkı Kuzuların Büyüme Performansının İncelenmesi
Authors: KUTLU Mehmet Ali , ÇELİK Şenol , KAYGUSUZOĞLU Erdal
Published: June 2022

Bu çalışmada Bingöl’de yetiştirilen Akkaraman ırkı kuzuların altıncı ay canlı ağırlığına (AW) ve sütten kesim ağırlığına (WW) yaş, cinsiyet ve doğum tipi gibi faktörlerin etkisi ile doğum ağırlığı (BW) üzerinde yaş ve cinsiyetin etkileri araştırılmıştır. Faktöriyel ANOVA testi sonucunda, AW değişkeni yaş, cinsiyet ve doğum tipi (p
Bazı Patates (Solanum tuberosum L.) Çeşitlerinin in vitro Şartlarda Tuzluluğa Toleransının Belirlenmesi
Authors: SÜRMEN Tuba , KUMLAY Ahmet Metin , KAYA Canan
Published: June 2022

Patates (Solanum tuberosum L.) in vitro ve in vivo şartlarda tuz stresine orta derecede hassasiyet gösteren tarla bitkilerinden biridir. Tuzluluk stresi patates yumru üretiminde önemli ve tahrip edici etkilere sahiptir. Bu nedenle, patates genotiplerinin tuz stresine karşı in vitro şartlarda denenmesi, tarla denemelerine alternatif yararlı bir araç olarak ortaya çıkmaktadır. Bu araştırmanın temel amacı, in vitro mikroçoğaltım tekniğini kullanarak bazı patates çeşitlerinin tuzluluk stres toleransına tepkisini ortaya koymaktır. Çalışmada Van Gogh ve Granola patates çeşitlerinin tek boğum kesimi eksplantları kullanılmış ve MS ortamına 0.0, 250, 500, 750, 1000, 1500 ve 2000 mg L-1 konsantrasyonlarında NaCl ilave edilmiştir. Bitkicikler 6 hafta süre ile uzun gün fotoperiyot (16 saat aydınlık, 8 saat karanlık) şartlarında tutulmuşlardır. Hasat edilen bitkiciklerde eksplant rejenerasyon oranı (%), bitkicik boyu (cm), boğum, yaprak ve kökçük sayıları, yaprak boyu ve eni (mm), sap kalınlığı (mm), kökçük uzunluğu (mm) ile bitki yaş ve kuru ağırlıkları (g) ölçümleri yapılmıştır. Elde edilen sonuçlardan en bitki rejenerasyın oranının 250 mg L-1 ve 750 mg L-1 NaCl içeren ortamlardan (%90.63) elde edilmiştir. Mikroçoğaltım yönünden önemli olan en uzun bitki boyunun kontrol (28.71 cm) ve 250 mg L-1 NaCl içeren ortamdan (27.99 cm) elde edildiği, Van Gogh çeşidinin (25.09 cm) Granola çeşidine (16.67 cm) göre daha uzun bitkicikler verdiği belirlenmiştir. En fazla kökçük sayıları 250 mg L-1 NaCl ortamından (73.38 adet) ve Van Gogh çeşidinden (76.18 adet) elde edilmiştir. En uzun kökçükler 2000 mg L-1 NaCl içeren ortamdan (11.36 cm) ve Van Gogh çeşidinden (9.45 cm) elde edilmiştir. Bütün bu verilere göre artan tuz konsantrasyonuna bağlı olarak bitkilerde vejetatif gelişmenin büyük oranda etkilendiği, ancak Van Gogh çeşidinin Granola çeşidine göre tuzlu ortamlara daha fazla tolerans gösterdiği belirlenmiştir.
Sodyum Pirition’un (Sodyum Omadin) Sıçan Karaciğer ve Böbrek Dokularındaki Akut Etkileri
Authors: ERDOĞAN Kenan
Published: June 2022

Bu araştırmada intraperitonal yolla uygulanan sodyum pirition (35 ve 70 mg kg-1, ip) ve serum fizyolojik (salin) (%0.09 NaCl 0.5 ml kg-1, ip)uygulanmasının sıçanlar üzerine 24 ve 96 saatlik sürelerde böbrek ve karaciğer dokuları üzerine histolojik etkileri araştırılmıştır. Araştırma sonucunda, kontrol grubu ile karşılaştırıldığında intraperitonal yolla uygulanan sodyum piritionun doz ve süre artışına bağlı histopatolojik değişimlere neden olan sitotoksik etkisinin olabileceği kanısına varılmıştır.
Understanding Variation in Adoption of Video Telehealth and Implications for Health Care Systems
Authors: Gately Megan , Quach Emma , Shirk Steven , Trudeau Scott
Published: June 2022

Background Telehealth has rapidly expanded since COVID-19. Veterans Health Administration (VHA), the largest integrated health care system in the United States, was well-positioned to incorporate telehealth across specialties due to existing policies and infrastructure. Objectives The objective of this study is to investigate predictors of occupational therapy (OT) practitioners’ adoption of video telehealth. Methods This study presents data from a convenience sample of VHA occupational therapy (OT) practitioners administered pre-pandemic, in fall 2019. Survey development was guided by the Promoting Action on Research Implementation in Health Services framework, and gathered clinician attitudes, experiences, and perspectives about video telehealth to deliver OT services. Items included telehealth usage, perceived effectiveness of specific OT interventions, and perceptions about evidence. Our outcome variable denoted practitioners’ level of adoption of video telehealth: telehealth users (adopters), non-users who want to use telehealth (potential adopters and reference group), and non-users who do not want to use telehealth (non-adopters). In multiple multinomial logistic regressions, we tested whether level of adoption was associated with years of VHA work experience and perceived strength of evidence. Results Of approximately 1455 eligible practitioners, 305 VHA occupational therapy practitioners participated in the survey (21% response rate). One hundred and twenty-five (41%) reported using video telehealth, whereas 180 (59%) reported not using video telehealth. Among non-users, 107 (59%) indicated willingness to adopt telehealth whereas 73 (41%) were not willing. More VHA work experience predicted higher odds of being an adopter than a potential adopter; perceptions of stronger evidence regarding video telehealth predicted higher odds of being a potential adopter than a non-adopter. Conclusion Clinician beliefs and years of experience exerted an influence on clinicians’ use or willingness to use video telehealth. Efforts to enhance adoption of video telehealth should address clinicians’ beliefs regarding the innovative nature of and organizational resources necessary to foster utilization.
Penerapan Konstruksi Ramping terhadap Waste pada Ruang Lingkup Manajemen Proyek (Studi Kasus: Proyek Pembangunan Gedung Auditorium di Yogyakarta)
Authors: Bhaskara Adwitya , Ginting Albert Atmaja , Masagala Alfatsya Mubian
Published: June 2022

Konstruksi ramping telah diterapkan banyak proyek, artinya dalam masa perencanaan proyek telah meminimalisir waste dengan efektif dan efisien. Tujuan penelitian ini untuk mengidentifikasi variabel penyebab waste yang paling dominan pada proyek dan mengetahui penerapan Konstruksi Ramping pada proyek. Dalam mencapai tujuan tersebut maka digunakan metode Teorema Bayes untuk menentukan probabilitas dari waste 5M ruang lingkup manajemen. Hasil dari analisis probabilitas waste bahwa variabel-variabel yang menyebabkan waste adalah tenaga kerja sulit untuk bekerja sama dalam satu tim kerja (18,18%), material datang ke lokasi terlalu cepat (20,00%), alat berat terlambat sampai di lapangan (15,69%), denda karena keterlambatan proyek (34,88%) dan kesalahan dalam pemilihan jenis objek struktur (19.35%). Kemudian hasil dari analisis pengisian kuesioner penerapan konstruksi ramping dan observasi di lapangan bahwa proyek ini telah menerapkan konstruksi ramping sebesar 94,44%.
Community Resilience Related to Community Resources Access to Peatland in Political Ecological Perspectives: A Case Study of Purun (Eleocharis dulcis) Craftmen in Ogan Komering Ilir, South Sumatera, Indonesia
Authors: Azni Ulfa Sevia , Alfitri  , Yunindyawati  , Riswani
Published: June 2022

Community resilience is widely used in managing natural resources and the environment as a means of system capacity to cope with stress. However, our findings show that resilience is not easily applied to common-pool resources (CPRs) such as peatlands, which are open access and full of importance. This is experienced by the community of purun craftsmen (Eleocharis dulcis) in Ogan Komering, Ilir Regency, South Sumatra, Indonesia. This paper was conducted to determine the community's social resilience in overcoming pressures originating from environmental, socio-economic, and political changes. We used a qualitative research method with a descriptive approach and obtained data through observation, in-depth interviews, and documentation. Our findings suggest that community resilience on peatlands is influenced by mechanisms to gain and maintain access to the resource. This mechanism is relatively limited, so it can be said that it is less robust, mainly if three threat scenarios co-occur, such as massive activity by companies, weak rules for managing, utilizing, and protecting resources, and extreme weather conditions. In conclusion, from these findings, we show that “access politics” and policy implications also play an essential role in increasing the resilience of socio-ecological systems in important peatland areas.
Exploring the Factors of Undergraduate Learners’ Engagement and Knowledge Sharing for Sustainable hMOOC Learning
Authors: Zhang Yunqing , Mangmeechai Aweewan
Published: June 2022

In the post-pandemic era, the application of MOOC is essential to improve the quality and flexibility of higher education. This study aims to explore how factors from personal, environmental, and social level influence learners’ engagement and knowledge sharing in the context of hybrid MOOC (hMOOC) learning. Through random sampling, this study adopted a self-administered questionnaire to survey undergraduate students in China based on structural equation modeling (SEM). The results revealed motivation belief, system and relational quality had positive effects on learner engagement while content, instructor and relational quality also exerted positive effects on knowledge sharing. Meanwhile, learner engagement positively influenced knowledge sharing in hMOOC learning. However, system quality significantly affected knowledge sharing and instructor quality significantly affected learner engagement. Furthermore, content quality indirectly affected learner engagement via motivation belief. And learner engagement mediated the relationship between motivation belief and knowledge sharing behavior. These findings suggested that instructors, MOOC technician and administrator should take into consideration personal, environmental, and social factors to redesign an active engaging and sharing learning environment for achieving hybrid learning success.