bluuebunny/crossref_metadata_2025 huggingface dataset:
Therapists’ and non‐therapists’ constructions of heterosex: A qualitative story completion study
Authors: Shah‐Beckley Iduna , Clarke Victoria , Thomas Zoe
Published: November 2018

Objectives

Little research has examined the discourses that shape therapists’ sense‐making around heterosex. This paper explores the discourses of sexuality and gender underpinning therapists’ and non‐therapists’ responses to a sexual experimentation scenario in a heterosexual relationship. It also considers the value of the novel technique of story completion (SC), in which participants are asked to write a story in response to a hypothetical scenario, for qualitative psychology and psychotherapy research.

Design

This research used a comparative SC design (Kitzinger & Powell, 1995). Participants were sequentially presented with and invited to complete two story stems: one in which a male character suggested ‘trying something new’ to his female partner and one in which the female character made the suggestion. The stems were otherwise identical.

Methods

A total of 100 SCs were written by 49 (28 female; 21 male) therapists and 51 (29 female; 22 male) non‐therapists. Participants were recruited mainly via UK‐based email lists and Facebook groups, and therapeutic training organizations, and the data were analysed using a feminist post‐structuralist thematic analysis (Braun & Clarke, 2006).

Results

Both groups of participants drew on heteronormative discourses of sexuality and gender to make sense of the stem. Engaging in sexual experimentation was often depicted as a demonstration of being normal. In some stories written by women, sex was framed as a site for negotiating ‘equality’ and reciprocity in relationships. Therapists were more likely than non‐therapists to frame ‘difficulties’ within relationships as opportunities for personal growth and increased emotional depth, and their stories included greater emotional complexity.

Conclusion

These findings raise questions about practitioner training and whether it results in therapists drawing on narrow and restrictive discourses of heterosex in clinical practice.

Practitioner points

Training on sexual issues is largely absent from non‐specialist practitioner training courses, which potentially means therapists are ill‐equipped to respond to clients’ anxiety about sexual issues. Evidence from this and other research indicates that therapists’ sense‐making around heterosexual sexual relationships is underpinned by narrow and restrictive discourses that entrench traditional gender relations and limit sexual agency.

Psychologists are increasingly taking up positions of clinical leadership and are looked to for models of best practice. Drawing on theorizations of sexual difficulties, and of anxieties about sexual practice, that challenge traditional gender and heteronorms, and the commodification and medicalization of sex, is important for effective psychological leadership relating to the treatment of sexual issues and the furthering of social justice agendas.
The lncRNA RMEL3 protects immortalized cells from serum withdrawal‐induced growth arrest and promotes melanoma cell proliferation and tumor growth
Authors: Cardoso Cibele , Serafim Rodolfo B. , Kawakami Akinori , Gonçalves Pereira Cristiano , Roszik Jason , Valente Valeria , Vazquez Vinicius L. , Fisher David E. , Espreafico Enilza M.
Published: November 2018

RMEL3 is a recently identified lncRNA associated with BRAFV600E mutation and melanoma cell survival. Here, we demonstrate strong and moderate RMEL3 upregulation in BRAF and NRAS mutant melanoma cells, respectively, compared to melanocytes. High expression is also more frequent in cutaneous than in acral/mucosal melanomas, and analysis of an ICGC melanoma dataset showed that mutations in RMEL3 locus are preponderantly C > T substitutions at dipyrimidine sites including CC > TT, typical of UV signature. RMEL3 mutation does not correlate with RMEL3 levels, but does with poor patient survival, in TCGA melanoma dataset. Accordingly, RMEL3 lncRNA levels were significantly reduced in BRAFV600E melanoma cells upon treatment with BRAF or MEK inhibitors, supporting the notion that BRAF‐MEK‐ERK pathway plays a role to activate RMEL3 gene transcription. RMEL3 overexpression, in immortalized fibroblasts and melanoma cells, increased proliferation and survival under serum starvation, clonogenic ability, and xenografted melanoma tumor growth. Although future studies will be needed to elucidate the mechanistic activities of RMEL3, our data demonstrate that its overexpression bypasses the need of mitogen activation to sustain proliferation/survival of non‐transformed cells and suggest an oncogenic role for RMEL3.
Identification and functional analysis of proteins in response to light intensity, temperature and water potential in Brassica rapa hypocotyl
Authors: Wang Hongfei , Shang Qingmao
Published: November 2018

Hypocotyl elongation is an early event in plant growth and development and is sensitive to fluctuations in light, temperature, water potential and nutrients. Most research on hypocotyl elongation has focused on the regulatory mechanism of a single environment factor. However, information about combined effects of multi‐environment factors remains unavailable, and overlapping sites of the environmental factors signaling pathways in the regulation of hypocotyl elongation remain unclear. To identify how cross‐talks among light intensity, temperature and water potential regulate hypocotyl elongation in Brassica rapa L. ssp. chinesis, a comprehensive isobaric tag for relative and absolute quantitation‐based proteomic approach was adopted. In total, 7259 proteins were quantified, and 378 differentially expressed proteins (DEPs) were responsive to all three environmental factors. The DEPs were involved in a variety of biochemical processes, including signal transduction, cytoskeletal organization, carbohydrate metabolism, cell wall organization, protein modification and transport. The DEPs did not function in isolation, but acted in a large and complex interaction network to affect hypocotyl elongation. Among the DEPs, phyB was outstanding for its significant fold change in quantity and complex interaction networks with other proteins. In addition, changes of sensitivity to environmental factors in phyB‐9 suggested a key role in the regulation of hypocotyl elongation. Overall, the data presented in this study show a profile of proteins interaction network in response to light intensity, temperature and water potential and provides molecular basis of hypocotyl elongation in B. rapa.
Sequential processing in the classic oddball task: ERP components, probability, and behavior
Authors: Fogarty Jack S. , Barry Robert J. , Steiner Genevieve Z.
Published: November 2018

This study compared the ERP components and behavior associated with the auditory equiprobable and classic oddball tasks, to relate the cognitive processing stages in those paradigms and continue the development of the sequential processing schema. Target and nontarget ERP data were acquired from 66 healthy young adults (Mage = 20.1, SD = 2.4 years, 14 male) who completed both equiprobable (target p = 0.5) and oddball tasks (target p = 0.3). Separate temporal PCAs were used to decompose the ERP data in each task and condition, and the similarity of the components identified in each condition was examined between tasks. Probability effects on component amplitudes and behavior were also analyzed to identify task differences in cognitive demands. A highly similar series of components was identified in each task, closely matching the schema: targets elicited N1‐3, N1‐1, PN, N2c, P3b, SW1, SW2; whereas nontargets elicited N1‐3, N1‐1, PN, N2b, P3a, SW1, SW2. N1‐1 and PN amplitudes increased as stimulus probability decreased, irrespective of the condition. N2b, P3b, SW1, and SW2 amplitudes also varied between tasks, illustrating task‐specific demands on those processing stages. These findings complemented the behavioral outcomes, which demonstrated greater accuracy and control in the classic oddball task. Overall, this study demonstrated comparable processing in the auditory equiprobable and classic oddball tasks, extending the generalizability of the schema and enabling further integration of the ERP theory associated with these tasks. This study also clarifies stimulus probability effects on the schema, providing important insight into the functionality of common ERP components.
Religious polarization, religious conflicts and individual financial satisfaction: Evidence from India
Authors: Migheli Matteo
Published: November 2018

The extant literature finds religion to be a major determinant of life satisfaction. However, in contexts characterized by religious tensions, the outcome may be very different. In particular, the literature shows that religious polarization has a major influence on some economic outcomes. The analysis presented in the paper tries to identify the impact of religious polarization on a major component of life satisfaction: financial satisfaction. The paper inquires how belonging to a minority religion and living in areas with different levels of religious polarization affect the individual satisfaction with the financial situation of the household. The results show that the members of minority religious groups are less satisfied than the members of the dominant group, and that the financial satisfaction decreases—for a given income—as the religious polarization increases.
An Evolutionary Approach to the Study of Collaborative Remembering?
Authors: Amici Federica
Published: November 2018

Hope and Gabbert (2008) and Jay and colleagues (in press) show us that collaborative remembering, in certain contexts, may result in incomplete and less accurate memories. Here, I will discuss the evolutionary origins of this behavior, linking it to phenomena such as social contagion, conformity, and social learning, which are highly adaptive and widespread across non‐human taxa.
Development and evaluation of a transfusion medicine genome wide genotyping array
Authors: Guo Yuelong , Busch Michael P. , Seielstad Mark , Endres‐Dighe Stacy , Westhoff Connie M. , Keating Brendan , Hoppe Carolyn , Bordbar Aarash , Custer Brian , Butterworth Adam S. , Kanias Tamir , Mast Alan E. , Kleinman Steve , Lu Yontao , Page Grier P. ,   for the National Heart, Lung, and Blood Institute Recipient Epidemiology Donor Evaluation Study (REDS)‐III
Published: November 2018

BACKGROUND

Many aspects of transfusion medicine are affected by genetics. Current single‐nucleotide polymorphism (SNP) arrays are limited in the number of targets that can be interrogated and cannot detect all variation of interest. We designed a transfusion medicine array (TM‐Array) for study of both common and rare transfusion‐relevant variations in genetically diverse donor and recipient populations.

STUDY DESIGN AND METHODS

The array was designed by conducting extensive bioinformatics mining and consulting experts to identify genes and genetic variation related to a wide range of transfusion medicine clinical relevant and research‐related topics. Copy number polymorphisms were added in the alpha globin, beta globin, and Rh gene clusters.

RESULTS

The final array contains approximately 879,000 SNP and copy number polymorphism markers. Over 99% of SNPs were called reliably. Technical replication showed the array to be robust and reproducible, with an error rate less than 0.03%. The array also had a very low Mendelian error rate (average parent–child trio accuracy of 0.9997). Blood group results were in concordance with serology testing results, and the array accurately identifies rare variants (minor allele frequency of 0.5%). The array achieved high genome‐wide imputation coverage for African‐American (97.5%), Hispanic (96.1%), East Asian (94.6%), and white (96.1%) genomes at a minor allele frequency of 5%.

CONCLUSIONS

A custom array for transfusion medicine research has been designed and evaluated. It gives wide coverage and accurate identification of rare SNPs in diverse populations. The TM‐Array will be useful for future genetic studies in the diverse fields of transfusion medicine research.
Ex vivo radiocontrast description of the caudal epigastric arteries in horses
Authors: Davis Joseph G. , Ragle Claude A. , Hanna Ashley , DeNome Andrew T.
Published: November 2018

Objective

To determine the location of the deep and superficial caudal epigastric arteries in relation to 3 midline positions and the relationship between the location of these arteries, body circumference, and body condition score.

Study design

Descriptive anatomical study.

Sample population

Nine horses, aged 1‐28 years (mean 10.61 ± 8.89 SD).

Methods

Body condition score and body circumference were measured prior to euthanasia. Angiographic studies of the deep and superficial caudal epigastric arteries were performed on resected abdominal walls. The distances between the deep and the superficial caudal epigastric arteries and 3 midline positions were measured. Correlations among these distances, body circumference, and body condition score were analyzed.

Results

The location of the deep caudal epigastric artery correlated with body circumference and body condition score at the umbilicus (r = 0.53 and 0.68, respectively), midpoint landmark (r = 0.79 and 0.83, respectively), and prepubic tendon attachment (r = 0.69 and 0.78, respectively). The course of this artery could be estimated by multiplying body circumference by 0.04 ± 0.02 at the umbilicus, 0.07 ± 0.01 at the midpoint landmark, and 0.03 ± 0.015 at the prepubic tendon attachment. The course of the superficial caudal epigastric artery did not correlate with anatomic landmarks.

Conclusion

The course of the deep caudal epigastric artery could be estimated at 3 midline landmarks on the basis of body circumference and body condition score in equine cadavers.

Clinical significance

Predicting the course of the caudal epigastric arteries in the equine abdomen based on correlation among location, body circumference, and body condition score may prevent iatrogenic damage during creation of laparoscopic portals.
Effects of intermittent hyperbaric exposure on endurance and interval exercise performance in well‐trained mice
Authors: Suzuki Junichi
Published: November 2018

New Findings

What is the central question of this study?

Intermittent hyperbaric exposure (1.3 atmospheres absolute with 20.9% O2) enhances endurance capacity by facilitating oxidative and glycolytic capacities in skeletal muscle. It remains unclear whether this strategy enhances endurance performance in well‐trained individuals.

What is the main finding and its importance?

Hyperbaric exposure with endurance training enhanced oxidative and glycolytic capacities and protein levels of mitochondrial transcription factor A, dynamin‐related protein‐1 and heat shock protein 70. Hyperbaric exposure with sprint interval training increased the proportion of type I muscle fibres and promoted capillary growth and muscle fibre hypertrophy. These results may lead to a new strategy for enhancing exercise capacity in well‐trained mice.

The study was designed to clarify the mechanisms by which hyperbaric exposure (1.3 atmospheres absolute with 20.9% O2) improves endurance and interval exercise capacities in highly trained mice. Male mice in the training group were housed in a cage with a wheel activity device for 7 weeks from 5 weeks old. Voluntary running markedly increased maximal endurance capacity by 6.4‐fold. Trained mice were then subjected to either endurance treadmill training (20–32.5 m min−1) or sprint interval training (5 s run–10 s rest, 30–42.5 m min−1) with (HypET or HypSIT, respectively) and without (ET or SIT, respectively) 1 h hyperbaric exposure for 4 weeks. Maximal endurance capacity was significantly increased by HypET and HypSIT, and maximal interval capacity was significantly enhanced by HypSIT. Peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha expression levels were markedly increased after HypET and HypSIT. Activity levels of 3‐hydroxyacyl‐CoA‐dehydrogenase, citrate synthase and phosphofructokinase in the red gastrocnemius muscle were increased more by HypET than by ET. Protein levels of mitochondrial transcription factor A, dynamin‐related protein‐1 and heat shock protein 70 were increased more by HypET than by ET. The proportion of type I fibres in the soleus muscle was remarkably increased by HypSIT. Capillary‐to‐fibre ratio values in the white gastrocnemius were increased more by HypSIT than by SIT. These results suggest that hyperbaric exposure has beneficial effects for endurance and interval training to improve exercise capacity in highly trained mice.
Internal Transcribed Spacer (ITS) sequences of some Kampimodromus (Acari: Phytoseiidae) species: Is Kampimodromus ragusai a valid species or a synonym of Kampimodromus aberrans?
Authors: Doker Ismail , Karut Kamil , Karaca Mete M. , Cargnus Elena , Kazak Cengiz
Published: November 2018

Taxonomy of the most important predatory mite family Phytoseiidae (Acari: Mesostigmata) is essentially based on morphological observations, and only a few studies use molecular approaches. In some cases, tiny morphological differences (e.g. number of teeth on cheliceral digits, presence of dorsal solenostomes) should be observed for accurate species identification. Kampimodromus ragusai Swirski & Amitai, originally described from Israel, was suspected as a junior synonym of K. aberrans (Oudemans) in an earlier study. The only difference between these two species is the presence or absence of a tooth on the movable digit (MD) of chelicera. In this study, we conducted molecular analyses, using the Internal Transcribed Spacer (ITS) marker, to determine whether K. ragusai is synonymous to K. aberrans or a valid species. DNA sequences of several populations of three other Kampimodromus species collected from Croatia and Italy were included to the study. ITS sequences of other Kampimodromus species deposited in the public GenBank database were also used. Results revealed a 5% genetic distance between K. ragusai and K. aberrans (Jukes & Cantor model). In the phylogenetic tree, K. ragusai is located in a different clade clearly separated from all other K. aberrans. Therefore, these results validate that K. ragusai and K. aberrans are altogether two distinct species. Presence or absence of a tooth on MD of chelicera is a reliable morphological character to differentiate these two species. Additionally, a GenBank sequence deposited as K. aberrans is identical to K. corylosus Kolodochka. This result clearly demonstrates the importance of combining molecular and morphological data to phytoseiid taxonomy, and the need to generate reliable data in publicly available gene bank databases.
Unbiased roughness measurements: Subtracting out SEM effects, part 2
Authors: Lorusso Gian F. , Rutigliani Vito , Van Roey Frieda , Mack Chris A.
Published: November 2018

The measurement of roughness of small lithographic patterns is biased by noise in the scanning electron microscopes (SEMs) used to make the measurements. Unbiasing the roughness measurement requires the measurement and subtraction of the image noise based on its unique frequency behavior. Improvement to prior white noise removal is achieved by applying a pink noise model. This pink noise removal technique was applied to roughness measurements made with different electron doses (frames of integration), different operating voltages, and different generations of SEM tools. Effective noise removal to create accurate unbiased estimates of the roughness was achieved over a wider range of SEM tool parameter settings than has been previously achieved. As a result, unbiased roughness measurements can now be used to characterize and improve stochastic variability in semiconductor lithography and patterning.
Free falling inside flattened spheroids: Gravity tunnels with no exit
Authors: Taillet Richard
Published: November 2018

A “gravity tunnel” is the name given to a fictitious deep shaft drilled inside the Earth so that objects dropped from the surface of the Earth would free fall without ever touching the walls. It is well known that because of the rotation of the Earth, such tunnels are not straight lines but instead they emerge westward of the antipodal point, when the Earth is approximated as a rotating sphere. In this article, we determine the shape of gravity tunnels by taking into account the polar flattening of the Earth resulting from its rotation. The Earth is described as a McLaurin spheroid, an exact equilibrium shape for a rotating homogeneous deformable body that provides a fair description of the actual shape of the Earth. It turns out that the gravitational force acting on an object located inside the spheroid has a simple form (it is harmonic), so that it is straightforward to compute analytically the free fall trajectories. This study follows a procedure presented several times in this journal and elsewhere, i.e., the trajectory is first computed in the geocentric (non-rotating) frame, and it is then analysed in the terrestrial (rotating) frame. We find that when the flattening of the Earth is taken into account, gravity tunnels have no exit: an object dropped from a point of the surface (other than on the equator or a pole) never reaches the surface again, unless the flattening has very specific (and unnatural) values. We also compute the deviations from the vertical for short falls and compare them to standard eastwards and southwards deviation expressions obtained with other modelizations of the gravity of the rotating Earth, in particular, for a rotating spherical body.
Feynman—Schwinger duality
Authors: Deser S.
Published: November 2018

Brief recollections of two giants of physics, their origins, similarities, and differences.
Low background noise increases cognitive load in older adults listening to competing speech
Authors: Meister Hartmut , Rählmann Sebastian , Walger Martin
Published: November 2018

This letter describes a dual-task paradigm sensitive to noise masking at favorable signal-to-noise ratios (SNRs). Two competing sentences differing in voice and context cues were presented against noise at SNRs of +2 and +6 dB. Listeners were asked to repeat back words from both competing sentences while prioritizing one of them. Recognition of the high-priority sentences was high and did not depend on the SNR. In contrast, recognition of the low-priority sentences was low and showed a significant SNR effect that was related to the listener's working memory capacity. This suggests that even subtle noise masking causes cognitive load in competing-talker situations.
Draft Genome Sequence of
Escherichia
Phage PGN829.1, Active against Highly Drug-Resistant Uropathogenic Escherichia coli
Authors: Chaudhary Naveen , Mohan Balvinder , Taneja Neelam
Published: November 2018

The
Escherichia
phage PGN829.1 was isolated from sewage of a tertiary care referral hospital in North India. It lyses multiple strains of highly drug-resistant uropathogenic
E. coli
.
Draft Genome Sequence of
Thermaerobacter
sp. Strain PB12/4term, a Thermophilic Facultative Anaerobic Bacterium from Bottom Sediments of Lake Baikal, Russia
Authors: Baturina Olga A. , Pavlova Olga N. , Novikova Angelina S. , Kabilov Marsel R. , Zemskaya Tamara I.
Published: November 2018

Here, we report the draft genome sequence of
Thermaerobacter
sp. strain PB12/4term, a thermophilic facultative anaerobic bacterium from the bottom sediments of Lake Baikal, Russia, associated with the discharge zone of gas-bearing fluids.
Complete Genome Sequence of Streptococcus agalactiae Serotype III, Multilocus Sequence Type 335 Strain HU-GS5823, Isolated from a Human Patient in Japan with Severe Invasive Infection
Authors: Nagaoka Kentaro , Konno Satoshi , Murase Kazunori , Kikuchi Taisei , Nakagawa Ichiro
Published: November 2018

Streptococcus agalactiae
is an important causal pathogen of neonatal and obstetric sepsis, and it may be involved in invasive infection in immunocompromised and elderly individuals. Here, we report the complete genome sequence of
Streptococcus agalactiae
serotype III strain HU-GS5823, which was isolated from a patient in Japan with an invasive infection.
Complete Genome Sequences of the Arcobacter cryaerophilus Strains ATCC 43158
T
and ATCC 49615
Authors: Miller William G. , Yee Emma , Bono James L.
Published: November 2018

Arcobacter cryaerophilus
was originally recovered from aborted bovine and porcine fetuses, but it has been subsequently isolated from meat, water, and human clinical samples. This study describes the complete whole-genome sequences of two
A. cryaerophilus
strains, ATCC 43158
T
(=A 169/B
T
=LMG 24291
T
) and ATCC 49615 (=CDC D2610 =LMG 10829).
Label-Free Digital Holo-tomographic Microscopy Reveals Virus-Induced Cytopathic Effects in Live Cells
Authors: Yakimovich Artur , Witte Robert , Andriasyan Vardan , Georgi Fanny , Greber Urs F.
Published: November 2018

This study introduces label-free digital holo-tomographic microscopy (DHTM) and refractive index gradient (RIG) measurements of live, virus-infected cells. We use DHTM to describe virus type-specific cytopathic effects, including cyclic volume changes of vaccinia virus infections, and cytoplasmic condensations in herpesvirus and rhinovirus infections, distinct from apoptotic cells. This work shows for the first time that DHTM is suitable to observe virus-infected cells and distinguishes virus type-specific signatures under noninvasive conditions. It provides a basis for future studies, where correlative fluorescence microscopy of cell and virus structures annotate distinct RIG values derived from DHTM.
Meningeal carcinomatosis secondary to a suspected pulmonary carcinoma in a cat and comparison with human literature
Authors: Crespo Virginia , Ortega Maria , Stabile Fabio , Di Palma Stefano , Fernández Yordan
Published: November 2018

A six‐year‐old male neutered domestic shorthair was referred because of decreased appetite, progressive weight loss and anisocoria. Neurological examination identified a right mydriatic pupil, non‐responsive to light, but no other neurological abnormalities or behavioural changes. Neuroanatomical localisation was to the right oculomotor nerve (parasympathetic component). MRI of the brain revealed a large mass affecting the meninges and intraparenchymal lesions in the cerebellum. CT of the thorax identified multiple nodules of different size within the pulmonary parenchyma and pleural and mediastinal effusion. Cytology of the pulmonary nodules revealed neoplastic cells consistent with pulmonary carcinoma, and histopathology of the meninges and brain revealed that the same epithelial population was infiltrating the meninges and the brain parenchyma. Based on these findings, meningeal carcinomatosis secondary to a suspected pulmonary carcinoma was hypothesised.
Genesis of the Wuxing Pt–Pd-rich Cu–Ni sulfide deposit in the eastern Central Asian Orogenic Belt: evidences from geochronology, elemental geochemistry, and Sr–Nd–Hf isotopic data
Authors: Sun Jing-gui , He Yun-peng , Han Ji-long , Wang Zhong-yu
Published: November 2018

The Wuxing Pt–Pd-rich Cu–Ni sulfide deposit in Heilongjiang Province, Northeast China, is located to the northeast of the Dunhua–Mishan fracture of the eastern Central Asian Orogenic Belt. The mafic–ultramafic complex consist of early-period hornblende–olivine pyroxenite, diopsidite, and hornblende pyroxenite and late-period gabbro and diabase units. An early-period hornblende pyroxenite yielded a zircon U–Pb age of 208.2 ± 2.6 Ma and a late-period diabase yielded a U–Pb age of 205.6 ± 1.1 Ma, with zircon εHf(t) values of +1.24 to +8.13. The early- and late-period lithofacies are relatively enriched in LILE (Rb, Ba, and Sr) and LREE, and variably depleted in HFSE (Nb, Ta). The whole-rock and single-mineral analyses of the early-period lithofacies yield (87Sr/86Sr)i ratios of 0.7055–0.7083 and εNd(t) ratios of −7.98–+3.10. These geochemical data suggest that the parental magmas of the Wuxing complex are high-Mg subalkaline basaltic in nature and were derived from an enriched mantle source. The magmas chamber formed after the injection of magma into the crust along with crustal contamination, producing early crystalline minerals and ore-bearing magmas. The rupturing of the magma chamber released evolved magmas, which then ascended and generated Pt–Pd-bearing lithofacies and Cu–Ni sulfide orebodies by fractional crystallization, accumulation, and liquation. During the late period, the residual magma invaded the early lithofacies and Cu–Ni orebodies. The fluids exsolved from the gabbroic magmas concentrated the mineralized metal elements and enhanced the precipitation of Pt–Pd-bearing veinlet-disseminated orebodies and Pt–Pd–Cu–Ni orebodies.
Pseudomonas species isolated from tobacco seed promote root growth and reduce lead contents in Nicotiana tobacum K326
Authors: Li Juan , Zheng Bufan , Hu Ruiwen , Liu Yongjun , Jing Yongfeng , Xiao Yunhua , Sun Min , Chen Wu , Zhou Qingming
Published: November 2018

Endophytic bacteria are generally helpful for plant growth and protection. We isolated from tobacco seeds three Pseudomonas strains (K03, Y04, and N05) that could produce siderophores, indole-3-acetic acid, and 1-aminocyclopropane-1-carboxylate deaminase, fix nitrogen, dissolve phosphorus and potassium, and tolerate heavy metals. In pot experiments, the three isolated strains significantly promoted root growth and increased the root enzyme activity in Nicotiana tobacum K326. Furthermore, bacterial inoculations increased the proportion of residual lead (Pb) by 8.36%–51.63% and decreased the total Pb content by 3.28%–6.38% in the contaminated soil during tobacco planting, compared with uninoculated soils. An effective decrease in Pb content was also found in tobacco leaves with bacterial inoculations. K03 inoculation decreased the Pb content in the upper leaves by 49.80%, and Y04 inoculation had the best effect, decreasing the Pb content in the middle leaves by 70.12%. Additionally, soil pH and root activity had significant effects on transformation and translocation of Pb. The study suggested that in response to Pb pollution in soil, a reasonable application of endophytes (e.g., Pseudomonas) might be a promising approach in promoting tobacco growth and reducing Pb content in tobacco, while simultaneously enhancing Pb stabilization in soils.
Do Americans differ in their willingness to ride in a driverless bus?
Authors: Winter Scott R. , Rice Stephen , Mehta Rian , Walters Nathan W. , Pierce Matthew B. , Anania Emily C. , Milner Mattie N. , Rao Natasha
Published: November 2018

The purpose of this study was to examine a person’s willingness to ride (WTR) in an autonomous bus. Across two studies, we presented participants with hypothetical scenarios about riding in a driverless city or inter-city bus. We manipulated who was onboard the bus (participant, romantic partner, or child), the location of the bus (seven different countries), and the type of driver (human or driverless). In Study 1, participants were less willing to ride a driverless city bus compared to one driven by a human driver. In Study 2, participants’ WTR scores were influenced by participant gender, the person on board, and location, with scores dropping dramatically when the bus was located outside of the USA, or when a child was on board. The current data suggest that Americans are not entirely ready for driverless buses, mainly when someone they care about is on board, or the bus is located outside the USA.
Grand unified theory with a stable proton
Authors: Fornal Bartosz , Grinstein Benjamín
Published: November 2018

We demonstrate that a phenomenologically viable four-dimensional grand unified theory with no proton decay can be constructed. This is done in the framework of the minimal nonsupersymmetric SU(5) GUT by introducing new representations and separating the physical quark and lepton fields into different multiplets. In such a theory all beyond Standard Model particles are naturally heavy, but one can tune the parameters of the model such that gauge coupling unification is achieved and some of the new particles are at the TeV scale and accessible at the LHC.
Electronic exchange-correlation, many-body effect issues on first-principles calculations of bulk SiC polytypes
Authors: Demmouche Kamel , Coutinho José
Published: November 2018

The first-principles Projector-Augmented Wave method (PAW) is used to investigate the electronic, phonon band structure and dielectric properties of four bulk silicon carbide (SiC) polytypes. We employ PAW pseudopotential density functional theory with Perdew, Burke and Ernzerhof (PBE) and hybrid HSE06 approximations of the exchange-correlation functional. Many-body effects are incorporated using the GW approximation of the self-interaction to study SiC properties. GW method in its single-shot variant, which is based on the many-body perturbation theory (MBPT), is used to calculate the quasi-particle (QP) energies of the band structure and the dielectric properties for different polytypes. The electronic band structure determination within GW method uses the Wannier procedure where a basis set of maximally localized Wannier function (MLWF) is constructed to interpolate the QP energies of few regular mesh k-points to the high-symmetry lines in Brillouin zone. As a consequence of QP correction to the Kohn–Sham energies, bandgap is increased by upto 3 eV in case of 4H–SiC, as compared to PBE bandgap. GW results are comparable to those of hybrid functionals and are in good agreement with the experimental results. The optical properties are then studied within PBE, HSE06 and include many-body effects. In addition, the phonon band structure has been investigated within HSE06 and compared to previous PBE results. We found good agreement with the previous theoretical results and the experimental available data.
The improvement of classification accuracy with denoising class autoencoder
Authors: Gu Congcong , Ji Zhicheng , Wang Yan
Published: November 2018

Denoising autoencoder is a data compression algorithm in deep learning, and it can successfully extract features which contain main information of the input data. However, this method is trained in an unsupervised manner and cannot aim at extracting the specified information. Therefore, the input data will be classified into a class label by main but not necessary information using traditional denoising autoencoder, and redundant information reduces the classification accuracy. To solve this problem, denoising class autoencoder presented in this paper is adopted to train a classification function and extract class features. Both the proposed approach and traditional methods are trained on MNIST handwritten digit database with mini-batch gradient descent, moreover the recognition result of the proposed approach demonstrates the effectiveness in comparison with conventional methods.
HEMODYNAMIC EFFECT OF OBSTRUCTION TO RENAL ARTERIES CAUSED BY STENT GRAFTS IN PATIENTS WITH ABDOMINAL AORTIC ANEURYSMS
Authors: LIU MING , SUN ANQIANG , DENG XIAOYAN
Published: November 2018

To investigate the hemodynamic effects of partial obstruction to the renal orifice caused by inappropriate stent-graft location. Pre-operative and deployment models of a stent graft with various degrees of obstruction to the renal orifice are constructed based on medical images of abdominal aortic aneurysm. Hemodynamics, including flow pattern, time-averaged wall shear stress (TAWSS), oscillatory shear index (OSI), as well as relative residence time (RRT) are analyzed using numerical simulations. Flow rate distributions are assessed and verified by in vitro experiments. Results show that partial blockage to the renal branch orifice leads to flow recirculation and vortices with low wall shear stress around the renal ostia, whereas OSI and RRT on the renal arteries increase with the degree of obstruction. While the in vitro experiment indicates a decreasing flow rate to the bilateral renal arteries as renal artery ostia are obstructed. In conclusion, obstruction to the renal arteries induced by an inappropriate stent graft location causes stenosis in the renal artery in the long term. This study reveals a possible pathological mechanism of renal complications due to the implantation of a stent graft.
DUTY-CYCLED SPINNING BASED 3D MOTION CONTROL APPROACH FOR BEVEL-TIPPED FLEXIBLE NEEDLE INSERTION
Authors: YAO QIN , ZHANG XUMING
Published: November 2018

Flexible needle has been widely used in the therapy delivery because it can advance along the curved lines to avoid the obstacles like important organs and bones. However, most control algorithms for the flexible needle are still limited to address its motion along a set of arcs in the two-dimensional (2D) plane. To resolve this problem, this paper has proposed an improved duty-cycled spinning based three-dimensional (3D) motion control approach to ensure that the beveled-tip flexible needle can track a desired trajectory to reach the target within the tissue. Compared with the existing open-loop duty-cycled spinning method which is limited to tracking 2D trajectory comprised of few arcs, the proposed closed-loop control method can be used for tracking any 3D trajectory comprised of numerous arcs. Distinctively, the proposed method is independent of the tissue parameters and robust to such disturbances as tissue deformation. In the trajectory tracking simulation, the designed controller is tested on the helical trajectory, the trajectory generated by rapidly-exploring random tree (RRT) algorithm and the helical trajectory. The simulation results show that the mean tracking error and the target error are less than 0.02[Formula: see text]mm for the former two kinds of trajectories. In the case of tracking the helical trajectory, the mean tracking error target error is less than 0.5[Formula: see text]mm and 1.5[Formula: see text]mm, respectively. The simulation results prove the effectiveness of the proposed method.
Host-Based Intrusion Detection System with System Calls
Authors: Liu Ming , Xue Zhi , Xu Xianghua , Zhong Changmin , Chen Jinjun
Published: November 2018

In a contemporary data center, Linux applications often generate a large quantity of real-time system call traces, which are not suitable for traditional host-based intrusion detection systems deployed on every single host. Training data mining models with system calls on a single host that has static computing and storage capacity is time-consuming, and intermediate datasets are not capable of being efficiently handled. It is cumbersome for the maintenance and updating of host-based intrusion detection systems (HIDS) installed on every physical or virtual host, and comprehensive system call analysis can hardly be performed to detect complex and distributed attacks among multiple hosts. Considering these limitations of current system-call-based HIDS, in this article, we provide a review of the development of system-call-based HIDS and future research trends. Algorithms and techniques relevant to system-call-based HIDS are investigated, including feature extraction methods and various data mining algorithms. The HIDS dataset issues are discussed, including currently available datasets with system calls and approaches for researchers to generate new datasets. The application of system-call-based HIDS on current embedded systems is studied, and related works are investigated. Finally, future research trends are forecast regarding three aspects, namely, the reduction of the false-positive rate, the improvement of detection efficiency, and the enhancement of collaborative security.
Erratum
Authors: Aspnes James , Attiya Hagit , Censor-Hillel Keren , Ellen Faith
Published: November 2018

This is an erratum for the article “Limited-Use Atomic Snapshots with Polylogarithmic Step Complexity” published in J. ACM 62(1): 3:1-3:22 (2015). The implementation of a MaxArray

k
×
h

object in Algorithm 2 does not guarantee linearizability. We give here a simple correction to the algorithm and its correctness proof.
Incorporating Multi-Level User Preference into Document-Level Sentiment Classification
Authors: Li Junjie , Li Haoran , Kang Xiaomian , Yang Haitong , Zong Chengqing
Published: November 2018

Document-level sentiment classification aims to predict a user’s sentiment polarity in a document about a product. Most existing methods only focus on review contents and ignore users who post reviews. In fact, when reviewing a product, different users have different word-using habits to express opinions (i.e., word-level user preference), care about different attributes of the product (i.e., aspect-level user preference), and have different characteristics to score the review (i.e., polarity-level user preference). These preferences have great influence on interpreting the sentiment of text. To address this issue, we propose a model called Hierarchical User Attention Network (HUAN), which incorporates multi-level user preference into a hierarchical neural network to perform document-level sentiment classification. Specifically, HUAN encodes different kinds of information (word, sentence, aspect, and document) in a hierarchical structure and imports user embedding and user attention mechanism to model these preferences. Empirical results on two real-world datasets show that HUAN achieves state-of-the-art performance. Furthermore, HUAN can also mine important attributes of products for different users.
Geometry of Interaction for MALL via Hughes--Van Glabbeek Proof-Nets
Authors: Hamano Masahiro
Published: November 2018

This article presents, for the first time, a Geometry of Interaction (GoI) interpretation inspired from Hughes--Van Glabbeek (HvG) proof-nets for multiplicative additive linear logic (MALL). Our GoI dynamically captures HvG’s geometric correctness criterion—the toggling cycle condition—in terms of algebraic operators. Our new ingredient is a scalar extension of the *-algebra in Girard’s *-ring of partial isometries over a Boolean polynomial ring with literals of eigenweights as indeterminates. To capture feedback arising from cuts, we construct a finer-grained execution formula. The expansion of this execution formula is longer than that for collections of slices for multiplicative GoI, hence it is harder to prove termination. Our GoI gives a dynamical, semantical account of Boolean valuations (in particular, pruning sub-proofs), conversion of weights (in particular, α-conversion), and additive (co)contraction, peculiar to additive proof-theory. Termination of our execution formula is shown to correspond to HvG’s toggling criterion. The slice-wise restriction of our execution formula (by collapsing the Boolean structure) yields the well-known correspondence, explicit or implicit in previous works on multiplicative GoI, between the convergence of execution formulas and acyclicity of proof-nets. Feedback arising from the execution formula by restricting to the Boolean polynomial structure yields autonomous definability of eigenweights among cuts from the rest of the eigenweights.
Jointly Minimizing the Expected Costs of Review for Responsiveness and Privilege in E-Discovery
Authors: Oard Douglas W. , Sebastiani Fabrizio , Vinjumur Jyothi K.
Published: November 2018

Discovery
is an important aspect of the civil litigation process in the United States of America, in which all parties to a lawsuit are permitted to request relevant evidence from other parties. With the rapid growth of digital content, the emerging need for “e-discovery” has created a strong demand for techniques that can be used to review massive collections both for “responsiveness” (i.e., relevance) to the request and for “privilege” (i.e., presence of legally protected content that the party performing the review may have a right to withhold). In this process, the party performing the review may incur costs of two types, namely,
annotation costs
(deriving from the fact that human reviewers need to be paid for their work) and
misclassification costs
(deriving from the fact that failing to correctly determine the responsiveness or privilege of a document may adversely affect the interests of the parties in various ways). Relying exclusively on automatic classification would minimize annotation costs but could result in substantial misclassification costs, while relying exclusively on manual classification could generate the opposite consequences. This article proposes a
risk minimization
framework (called MINECORE, for “minimizing the expected costs of review”) that seeks to strike an optimal balance between these two extreme stands. In MINECORE (a) the documents are first automatically classified for both responsiveness and privilege, and then (b) some of the automatically classified documents are annotated by human reviewers for responsiveness (typically by junior reviewers) and/or, in cascade, for privilege (typically by senior reviewers), with the overall goal of minimizing the expected cost (i.e., the
risk
) of the entire process. Risk minimization is achieved by optimizing, for both responsiveness and privilege, the choice of which documents to manually review. We present a simulation study in which classes from a standard text classification test collection (RCV1-v2) are used as surrogates for responsiveness and privilege. The results indicate that MINECORE can yield substantially lower total cost than any of a set of strong baselines.
Parallel Cost Analysis
Authors: Albert Elvira , Correas Jesús , Johnsen Einar Broch , Pun Ka I. , Román-Díez Guillermo
Published: November 2018

This article presents
parallel cost analysis
, a static cost analysis targeting to over-approximate the cost of parallel execution in distributed systems. In contrast to the standard notion of
serial cost
, parallel cost captures the cost of synchronized tasks executing in parallel by exploiting the true concurrency available in the execution model of distributed processing. True concurrency is challenging for static cost analysis, because the parallelism between tasks needs to be soundly inferred, and the waiting and idle processor times at the different locations need to be accounted for. Parallel cost analysis works in three phases: (1) it performs a
block-level
analysis to estimate the serial costs of the blocks between synchronization points in the program; (2) it then constructs a
distributed flow graph
(DFG) to capture the parallelism, the waiting, and idle times at the locations of the distributed system; and (3) the parallel cost can finally be obtained as the
path of maximal cost
in the DFG. We prove the correctness of the proposed parallel cost analysis, and provide a prototype implementation to perform an experimental evaluation of the accuracy and feasibility of the proposed analysis.
ЗМІНИ БІОХІМІЧНИХ ПОКАЗНИКІВ І ФУНКЦІОНАЛЬНОЇ АКТИВНОСТІ СЕРЦЯ ВИСОКО- І НИЗЬКОСТІЙКИХ ДО ГОСТРОЇ ГІПОКСИЧНОЇ ГІПОКСІЇ ЩУРІВ РІЗНОЇ СТАТІ ПРИ ІММОБІЛІЗАЦІЙНОМУ СТРЕСІ
Authors: Ordynskyi Iu. M. , Denefil O. V.
Published: November 2018

Вступ. Визначення механізмів ушкоджувального впливу стресу на серце в осіб з різною реактивністю може сприяти розробці індивідуальних методів корекції.

Метадослідження – визначити вплив іммобілізаційного стресу на зміни пероксидного окиснення ліпідів, антиоксидантного захисту та показники електрокардіограм у щурів різної статі з високою і низькою стійкістю до гіпоксії (ВГ та НГ).

Методи дослідження. Стрес моделювали 4 рази шляхом одногодинної іммобілізації щурів спинкою донизу з інтервалом 24 год. У серці визначали концентрацію дієнових і трієнових кон’югатів, шиффових основ, ТБК-активних продуктів, активність супероксиддисмутази, каталази. Реєстрували електрокардіограми.

Результати й обговорення. У контрольних ВГ самців, порівняно з НГ, виявлено нижчу активність процесів пероксидного окиснення ліпідів, вищу активність супероксиддисмутази, у ВГ самиць порівняно з НГ – більше продуктів пероксидного окиснення ліпідів, супероксиддисмутази, меншу активність каталази. Іммобілізація призвела до розвитку окиснювального і карбонільного стресу, більше в самців порівняно із самицями. При дослідженні електрокардіограм тільки за умов стресу у ВГ самиць збільшились амплітуда зубця R, відхилення SТ відносно ізолінії, у НГ зросла частота серцевих скорочень, зменшилася тривалість інтервалів RR і QTc.

Висновки. Інтервальна іммобілізація щурів призводить до окиснювального та карбонільного стресу в серці, але механізми його розвитку залежать від стійкості до гіпоксії і статі. При іммобілізаційному стресі зміни на електрокардіограмах відмічено тільки в самиць.