bluuebunny/crossref_metadata_2025 huggingface dataset:
Alternative approach to moments of order statistics from one-parameter Weibull distribution
Authors: Rai Piyush Kant , Sirohi Anu
Published: March 2020

The Weibull distribution is used to describe various observed failures of phenomena and widely used in survival analysis and reliability theory. Sometimes it is very difficult to compute moments of such distributions due to various reasons for e.g. analytical issues, multi parameter cases etc. This study presents the computation of the moments and the expected value of the product of order statistics in the sample from the one-parameter Weibull distribution. An alternative approach in connection to survival function is used to obtain these moments and expected values. In addition the characteristic function of the above distribution is also obtained in the form of gamma functions. Further an illustration is shown to find the first two moments and expected value of the product of order statistics by using this approach.
EL PEI, un instrumento pedagógico que al reflexionar sobre la memoria colectiva del conflicto armado posibilita un aprendizaje en torno al dolor y sufrimiento
Authors: Mosquera Mosquera Carlos Enrique , Rodríguez Lozano María Nelsy
Published: March 2020

Al interpretar el Proyecto Educativo Institucional (PEI) a partir de las categorías de subjetividad política y memoria colectiva del conflicto armado, encontramos que: i) la escuela haciendo uso de los 5 componentes del PEI puede hacer pedagogía de la memoria sobre las dimensiones del conflicto armado, ii) la escuela puede resignificar los actos cívicos creando actividades pedagógicas que comporten nuevos sentidos sobre la violencia de pais al motivar la reflexión en los sujetos educativos, iv) es posible una educación desde  el lenguaje poético como grito y silencio de las víctmas, v) haciendo pedagogía de la memoria del conflicto armado, la escuela puede propiciar la unión en la comunidad educativa en torno al dolor y sufrimiento, posibilitando una reelaboración imaginativa del dolor físico a sufrimiento, constituyéndose éste, en un tipo de enseñanza y apredizaje.
Ecología y educación: ¿apología del mercado?
Authors: Barrera Quiroga Diego Mauricio
Published: March 2020

El proyecto de la naturaleza y el proyecto del conocimiento han sido intervenidos por la razón como instrumento de la acumulación de la riqueza y el poder. La hermana naturaleza, a la cual pertenecemos, ha sido convertida en recursos extraíbles y utilizables, no como bienes de uso para un mejor vivir, sino como valor de cambio al servicio de la acumulación del capital, de allí su deterioro (y el nuestro). Ahora bien, si es la razón de la producción para el mercado, la que condujo al deterioro ambiental y a la fragmentación del saber y a la valoración ciega de lo instrumental como conocimiento prevalente, bien vale hacer un alto en el camino y, en las casas del saber, volver a pensar en libertad dos puntos nodales: el equilibrio de la naturaleza y el desarrollo del saber para la emancipación.
La reforma tributaria de 2016 y los nuevos recursos para el sistema judicial en el marco del postconflicto en Colombia
Authors: Lozano Lozano Janeth , Céspedes-González Anderson Iván , González-Martínez Jurieth Andrea , Amaya-Echeverry Angie Marcela
Published: March 2020

La reforma tributaria del 2016 y la inclusión de rubros que contribuyan al logro de financiación de procesos que se deben atender para consolidar la paz, es una necesidad que bien administrada puede dar resultados favorables para llegar a la reconciliación, la paz, la democracia y la estabilidad política después del conflicto armado de más de 60 años en el país.
Adolescentes infractores y promoción de acciones prosociales: una tarea pendiente
Authors: Galván-Moya Alexander Eliécer , Durán Palacio Nicolasa María
Published: March 2020

El diseño de las políticas nacionales, los modelos de tratamiento y los sistemas judiciales de menores, se encaminan hacia la prevención del delito y su reinserción familiar y social. Sin embargo, la región de AméricaLatina y el Caribe presenta los mayores índices de delincuencia y víctimas de crímenes entre la población de niños y adolescentes. Por ello ahondaremos en una exploración analítica de las nociones y constructosteóricos que describen las intervenciones socioeducativas y tratamientos, orientados hacia la promoción de acciones prosociales en adolescentes infractores de la ley, en programas de resocialización.
Politólogos. Subcampos y criterios para una propuesta de educación profesional
Authors: Duque Daza Javier
Published: March 2020

Este artículo realiza un análisis de las tendencias de educación de politólogos, sus fundamentos, orientaciones, subcampos y líneas centrales de desarrollo. A partir de este análisis se propone los fundamentos y criterios que pueden ser considerados en el diseño de una propuesta curricular para el pregrado en ciencia política. El argumento central es que en cualquier disciplina los nuevos miembros son educados a partir de ciertos estándares sobre teorías y conceptos, metodologías y técnicas, que le los diferencias de otras disciplinas y profesiones. Aunque hay diferencias en los énfasis formativos, en las preferencias teóricas, en las concepciones y valores, y la disciplina supone el pluralismo teórico y metodológico, existen componentes mínimos básicos comunes a todos los politólogos que deben hacer parte de los diseños curriculares.
El comportamiento dual de la crisis económica en las trayectorias laborales de inmigrantes colombianos en Madrid (España)
Authors: Monguí Monsalve Mónica María
Published: March 2020

El artículo analiza el comportamiento de la crisis económica en las trayectorias laborales de colombianos en Madrid, examinando los dos segmentos del mercado de trabajo español. Recurriendo al método biográfico, se constata que la crisis irrumpe como elemento definitivo en el re-direccionamiento laboral. Dicha dinámica se muestra tanto para trabajadores del segundo segmento laboral, como para aquellos ubicados en el segmento primario, desarrollando distintas estrategias que permiten para unos, resistir las inclemencias del ciclo económico, y para otros, superar estos obstáculos. El capital social y la situación administrativa se muestran como mecanismos decisivos para afrontar este contexto.
Orientaciones emocionales colectivas sobre el conflicto armado y sus actores como barreras para la construcción de la paz y la reconciliación en Colombia
Authors: Villa Gómez Juan David , Rúa Álvarez Susana , Serna Natalí , Barrera Machado Daniela , Estrada Atehortúa Carlos Esteban
Published: March 2020

El presente artículo de investigación analiza orientaciones emocionales colectivas de carácter político como barreras psicosociales para la construcción de la paz y la reconciliación en Colombia.  Se realizaron 55 entrevistas semiestructuradas y en profundidad a ciudadanos del común en la ciudad de Medellín, de las que emergieron discursos relacionados con estas orientaciones emocionales, dirigidas al proceso de negociación política del conflicto armado entre el gobierno colombiano y la guerrilla de las Fuerzas Armadas Revolucionarias de Colombia – Ejército del Pueblo (FARC- EP).  Se identificaron diversas orientaciones emocionales como ira, indignación y odio, dirigidas hacia las FARC, especialmente por los participantes que se mostraron en desacuerdo.  Mientras que, quienes estaban de acuerdo, en menor medida expresaron este tipo de emociones hacia paramilitares. Sin embargo, hacia la fuerza pública, los tres grupos categorizados expresaron orientaciones emocionales de admiración, orgullo y sentimiento de patriotismo. De otro lado, la esperanza y la empatía como posibilitadoras de escenarios de transformación del conflicto armado primaron en quienes se encontraban de acuerdo.  Finalmente, la tristeza y el dolor emergieron en la mayoría de los participantes, pero en quienes estaban de acuerdo se asoció con solidaridad hacia las víctimas y deseo de transformar la guerra en Colombia por la vía de la negociación política.
Geopolítica del Conocimiento y Decolonialidad: ¿Está el eurocentrismo puesto a prueba?
Authors: Bonilla C Daniel
Published: March 2020

El eurocentrismo ha fundado su hegemonía como centro de pensamiento mundial en una relación jerárquica que ha gozado de pocos y débiles retadores. A pesar de los esfuerzos de decolonizar la creación del conocimiento no se evidencia aún un cambio significativo en las estructuras geopolíticas del conocimiento global. Si bien China se presenta como un desafío, una de sus estrategias para lograr la aceptación en el mundo ha sido a su vez, su occidentalización.
Emociones sociales y políticas en la construcción y la obstrucción de la paz en ciudadanos de estrato social medio-alto de la ciudad de Bogotá
Authors: Villa Gómez Juan David , Rodríguez Díaz Marcela , Gaitán Lee Laura , González Prieto María Alejandra , Haber Mariño Juana , Roa Sierra Juanita
Published: March 2020

Respecto de la configuración de orientaciones emocionales colectivas (OEC) de carácter político, como barreras psicosociales para la construcción de paz y la reconciliación en personas de la ciudad de Bogotá, desde una perspectiva de género, se lograron identificar distintas emociones como: tristeza y dolor; rabia, indignación y odio; miedo, angustia, desconfianza e incertidumbre; resentimiento y asco; inconformidad, preocupación y decepción; indiferencia, impotencia, frustración y desesperanza; esperanza, felicidad, optimismo y empatía; patriotismo, seguridad, gratitud y admiración, frente al conflicto armado, sus actores, el acuerdo de paz y el futuro del país. A partir de éstas, es posible concluir que algunas OEC se constituyen como barreras psicosociales de acuerdo con la manera en que se vivencian en las y los participantes.
Psychosocial Risk Factors: its Relation with Social Cognition, Emotional Regulation and Well-Being
Authors: Urrego Betancourt Yaneth , Castro Muñoz John Alexander
Published: March 2020

In Colombia, an increase of suicidal behavior in adolescents caused by personal and environmental factors is evidenced. This quantitative, descriptive, correlational research aimed to establish the existing relationship between social cognition, perception of the quality of relationships and emotional regulation with the variables of psychosocial risk, suicide risk and level of psychological well-being in adolescents in contexts of high socioeconomic vulnerability of Bogotá. A total of 155 adolescents were selected through nonprobabilistic sampling at convenience, with ages between 13 and 17 years (M = 14.47 and DE = 1.03). The results allowed observing the existence of significant relationships between the study variables. From a linear regression analysis, the emotional bond and emotional self-regulation had a higher level of explanation about the perception of well-being and the psychosocial risk associated with suicide. Finally, the results and implications of a greater participation of the emotional bond in comparison to that of social cognition in adolescence are discussed, in order to formulate programs that promote well-being and prevent risk.
Loss Aversion as a Potential Factor in the Sunk-Cost Fallacy
Authors: Tait Veronika , Miller Harold L.
Published: March 2020

The sunk-cost fallacy (SCF) occurs when an individual makes an investment with a low probability of a payoff because an earlier investment was made. The investments may be time, effort, or money. Previous researchers showed that larger prior investments were more likely to lead to the SCF than lower investments were, though little research has been focused on comparing investment types. There are several theories of the SCF, but few have implicated loss aversion, the higher sensitivity to losses than to gains, as a potential factor. We studied the differential effects of investment amount and type on the occurrence of the SCF and explored loss aversion as a potential explanation of these differences. There were 168 participants, who completed a sunk-cost task as well as an endowment-effect task, which was a measure of loss aversion. A 3×3 mixed-design ANCOVA was used in which the SCF score was the dependent variable and loss-aversion scores were used as a covariate. The SCF occurred most often with money, less with time, and least with effort. Loss aversion displayed a weak negative relation to the SCF.
Attachment Style Classification Questionnaire for latency age: Psychometrics properties of Argentine Sample
Authors: Richaud María Cristina , Mesurado Belén , Minzi María Paula
Published: March 2020

The purpose of this article was to perform a psychometric study of the Attachment Style Classification Questionnaire (ASCQ) in Spanish language. This paper included three studies. The objectives of study 1 were to analyze the discriminative power of items, to carry out an EFA to determine the structure of the questionnaire, and to calculate the internal consistency of factors. The objectives of study 2 were to test the questionnaire structure through a CFA, and to determine if the model obtained was invariant between sex and age. The objective of Study 3 was to study the convergent validity. The three studies were carried out with three different samples of 180, 200, and 425 Argentinian children, aged 9 to 12 years, respectively. The results confirm the three factor structure of the adapted questionnaire, showing good psychometric properties (satisfactory internal consistency and adequate validity).
The Effects of Parenting Styles on Internalizing and Externalizing Behaviors: A Mexican Preadolescents Study
Authors: Fuentes-Balderrama Jaime , Cruz del Castillo Cinthia , Ojeda García Angélica , Díaz Loving Rolando , Turnbull Plaza Bernardo , Parra Cardona José Rubén
Published: March 2020

Parental practices such as inconsistent discipline, psychological control, and imposition have been linked to the development of internalizing and externalizing problem behaviors in preadolescents. This study aimed to identify the association these practices had on Mexican preadolescent problem behaviors through Structural Equation Modeling. The sample consisted of 306 elementary students from three public schools in Mexico City (age M = 10, SD = 0.92). Students completed subscales from the Parental Practice Scale, the Alabama Parenting Questionnaire, and the Strengths and Difficulties Questionnaire. Paternal imposition and maternal psychological control were significant predictors for internalizing problems, while inconsistent discipline was a significant predictor of externalizing problems. The results highlight that although parental practicevalues might differ across cultures, their association to problem behaviors are similar.
Moderation of Islamic Education as an Effort to Prevent Radicalism (Case Study of FKUB Singkawang City, Kalimantan, Indonesia)
Authors: Widodo Asrip
Published: March 2020

Radicalism threatens harmony and unity. We need a holistic deradicalization effort by various elements of the nation. One element that has a strategic role is the Forum for Religious Harmony (FKUB). The study was conducted to reveal the role of FKUB Singkawang City in campaigning for moderation of Islamic education for the community as an effort to prevent radicalism, thus delivering this city as the number one most tolerant city in Indonesia. The method used is a qualitative field (Field Research), researchers go directly to the field to obtain data and information from data sources. Data were collected through direct interviews with the Chairperson of FKUB Singkawang City, FKUB documentation, Social Media and direct observation to the research location. The results showed that FKUB was able to realize moderation of Islamic education outside of educational institutions with dialogue and advocating strategic.Radikalisme mengancam harmoni dan persatuan. Kita membutuhkan upaya deradikalisasi holistik oleh berbagai elemen bangsa. Salah satu elemen yang memiliki peran strategis adalah Forum Kerukunan Umat Beragama (FKUB). Studi ini dilakukan untuk mengungkap peran FKUB Kota Singkawang dalam mengkampanyekan moderasi pendidikan Islam bagi masyarakat sebagai upaya mencegah radikalisme, sehingga menjadikan kota ini sebagai kota nomor satu yang paling toleran di Indonesia. Metode yang digunakan adalah bidang kualitatif (Field Research), peneliti pergi langsung ke lapangan untuk memperoleh data dan informasi dari sumber data. Data dikumpulkan melalui wawancara langsung dengan Ketua FKUB Kota Singkawang, dokumentasi FKUB, Media Sosial dan observasi langsung ke lokasi penelitian. Hasil penelitian menunjukkan bahwa FKUB mampu mewujudkan moderasi pendidikan Islam di luar lembaga pendidikan dengan dialog dan advokasi strategis.
The Implementation of Role of Kuttab Al-Fatih (KAF) Philosophy in Islamic Character Education
Authors: Hafnidar Hafnidar , Mansor Rosnidar , Nichiappan Suppiah
Published: March 2020

The aim of study was to understand about the implementation of role of kuttab al fatih (KAF) philosophy in islamic character education. This research used qualitative method. The study revealed that the KAF philosophies are "the faith before the Quran” “the adab before the knowledge" and “the knowledge before the actions (‘amal), which are believed to aid KAF to achieve its vision and mission. The implementation of KAF Philosophies in Islamic character education creates a solid foundation of faith which contains basic values for students who contain character good personalities such as obedient, responsible, disciplined, hard-working, long term concentration or focus, away from prohibitions, vices, sincere, be grateful, and motivated because of Allah. KAF philosophies delivered to all parties in KAF included students, parents, teachers, management, staff Foundation, cleaning service and driver. AbstrakTujuan dari penelitian ini adalah untuk memahami tentang implementasi peran filosofi kuttab al fatih dalam pendidikan karakter Islami. Penelitian ini menggunakan metode kualitatif. Studi ini mengungkapkan bahwa filosofi KAF adalah "Iman sebelum Quran" "Adab sebelum Ilmu""Ilmu sebelum tindakan (amal), yang diyakini membantu KAF untuk mencapai visi dan misinya. Penerapan KAF Philosophies dalam pendidikan karakter Islam menciptakan fondasi iman yang solid yang berisi nilai-nilai dasar bagi siswa yang mengandung karakter kepribadian yang baik seperti taat, bertanggungjawab, disiplin, pekerja keras, konsentrasi atau fokus jangka panjang, jauh dari larangan, kejahatan, tulus, bersyukur, dan termotivasi karena Allah. Filosofi KAF disampaikan kepada semua pihak di KAF termasuk siswa, orang tua, guru, manajemen, staf Yayasan, layanan kebersihan dan sopir.
THE RELATIONSHIP BETWEEN TRUNK ASSESSMENTS AND QUALITY OF LIFE IN ADOLESCENT IDIOPATHIC SCOLIOSIS FOLLOWING SURGERY
Authors: ÖZTÜRK Ferhat , DENİZ Hande Güney , AYVAZ Mehmet , DEMİRKIRAN Halil Gökhan , KINIKLI Gizem İrem
Published: March 2020

Purpose: There is a lack of evidence about trunk muscle endurance, range of motion (ROM), flexibility
and quality of life (QoL) in subjects with adolescent idiopathic scoliosis (AIS) following posterior
instrumentation and fusion (PIF) surgery. The study aimed to compare trunk muscle endurance, ROM,
flexibility, and QoL of the AIS subjects with lumbar or thoracic level after surgery. It also investigated
the relationship between trunk muscle endurance, ROM, flexibility, and QoL in subjects with AIS.
Methods: Twenty subjects aged between 10-18 years (mean age=15.55±1.46 years) who underwent
PIF surgery before 1-3 years were included. The subjects were divided into two groups as a thoracic
(n=10) and lumbar group (n=10) according to the PIF surgery level. The ROM was assessed using a
universal goniometer, flexibility with sit and reach test and lateral bending, trunk extensor muscle
endurance assessed with Biering-Sorensen test, trunk flexor muscle endurance with the Kraus-Weber
test, and the QoL through the Scoliosis Research Society-22 revised (SRS-22r) scale.
Results: There was significant difference between the two groups in lateral flexion ROM and lateral
bending results (p<0.05). Thoracic group showed better results in the lateral flexion ROM and lateral
bending test. Trunk flexor muscle endurance was found correlated with extension ROM (r=0.718,
p=0.001), flexion ROM (r=0.414, p=0.007), right lateral flexion ROM (r=0.721, p=0.001), and left lateral
flexion ROM (r=0.581, p=0.007). Trunk extensor muscle endurance was found correlated with right
rotation ROM (r=0.511, p=0.021), left rotation ROM (r=0.410, p=0.073), SRS-22r total score (r=0.677,
p=0.001) and SRS-22r pain score (r=0.554, p=0.011).
Conclusion: Trunk muscle endurance is essential for body posture and QoL after surgery. These
subject’s physiotherapy and rehabilitation programs should focus on developing trunk muscle endurance
and flexibility to increase QoL following PIF surgery.
THE DOSE INDEX IS RELATED WITH MUSCLE DYSFUNCTION, ACTIVITIES OF DAILY LIVING, AND QUALITY OF LIFE IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Authors: ÇAKMAK Aslıhan , ÇALIK KÜTÜKCÜ Ebru , ARIKAN Hülya , VARDAR YAĞLI Naciye , SAĞLAM Melda , İNAL İNCE Deniz , ÖKSÜZ Çiğdem , SAVCI Sema , DÜGER Tülin , BOZDEMİR ÖZEL Cemile , SONBAHAR ULU Hazal , TEKERLEK Haluk , ÇÖPLÜ Lütfi
Published: March 2020

Purpose: Composite measures have potential to account for many of the facets of disease in chronic obstructive pulmonary disease (COPD). The purpose of this study was to investigate the relationship between the DOSE (Dyspnea, Obstruction, Smoking, Exacerbation) Index which is a multi-component assessment tool and handgrip and respiratory muscle strength, activities of daily living (ADL) and health-related quality of life in patients COPD. Methods: Forty-five patients with COPD (30 males, 15 females, mean FEV1 =50.60±16.00%) were included. The DOSE Index was calculated using the modified Medical Research Council dyspnea scale, obstruction level, smoking status, and exacerbation rate. Inspiratory and expiratory muscle strength (MIP and MEP) was measured using a mouth-pressure device. Handgrip strength was determined using hand dynamometer. Activities of daily living were evaluated using the London Chest Activity of Daily Living Scale (LCADL), and quality of life was assessed using the diseasespecific COPD Assessment Test (CAT). Results: The DOSE Index score was related with handgrip strength (r=-0.388, p=0.009), MIP (r=- 0.323, p=0.033), LCADL-physical activity score (r=0.314, p=0.038), LCADL-leisure activities score (r=0.397, p=0.008), and CAT score (r=0.435, p=0.003). Conclusion: Increased multi-component disease severity is related to decreased handgrip and respiratory muscle strength, physical activity and leisure time activities of daily living, and worse health-related quality of life in COPD patients. The DOSE Index, a simple disease severity assessment tool, is a convenient and practical tool for assessment in pulmonary rehabilitation programs.
ASEMPTOMATİK HALLUKS VALGUSLU BİREYLERDE TEK AYAK ÜZERİ DENGE PERFORMANSININ İNCELENMESİ
Authors: TAŞ Serkan , BEK Nilgün , ÇETİN Alp
Published: March 2020

Amaç: Bu çalışmanın amacı, halluks valguslu (HV) bireylerde tek ayak üzeri denge performansının

araştırılarak sağlıklı kontrol grubu ile karşılaştırılmasıydı.

Yöntem: Bu çalışmaya, 20-57 yaş aralığında (32,57±10,15 yıl) iki erkek ve 21 kadın olmak üzere toplam

23 asemptomatik HV olan birey dahil edildi. Kontrol grubu ise 19-58 yıl yaş aralığında (33,36±10,53

yıl) iki erkek ve 23 kadın olmak üzere 25 bireyden oluşturuldu. Bireylerin ayak başparmağı pozisyonu

Manchester Skalası kullanılarak, halluks açısı ise gonyometre ile değerlendirildi. Tek ayak üzerinde

denge performansı ve postüral salınım miktarının ölçümü Biodex Denge Sistemleri kullanılarak

değerlendirdi. Tek ayak üzerinde denge performansının değerlendirilmesi amacıyla denge skorları

anteroposterior, mediolateal ve ortalama skor olmak üzere hesaplandı. Ayrıca testler esnasında, denge

merkezinden sapmaların standart deviasyonu anteroposterior ve mediolateral yönde hesaplandı.

Sonuçlar: Her iki grubun ortalama değerleri, anteroposterior ve mediolateral skorları arasında

anlamlı fark yoktu (p>0,05). Her iki gruba ait ortalama değerler, anteroposterior ve mediolateral

yönde denge merkezinden sapmaların standart deviasyonu da birbirine benzerdi (p>0,05). Ayak

parmağı halluks açısı ile ortalama, anteroposterior ve mediolateral skor arasında anlamlı ilişki yoktu

(p>0,05). Bireylerin yaşı ile değerlendirilen denge parametreleri arasında ilişki bulunmaz iken (p>0,05),

bireylerin boy, vücut ağırlığı ve vücut kütle indeksi (VKİ) değerleri ile denge skorları arasında düşük

düzeyden kuvvetliye değişen ilişki olduğu belirlendi (r=0,314-0,692, p
Plant water resource partitioning and xylem-to-leaf deuterium enrichment in Lanzhou, northwest China
Authors: Du Qinqin , Zhang Mingjun , Wang Shengjie , Argiriou Athanassios A. , Che Cunwei , Zhao Peipei , Ma Zhuanzhuan , Su Pengyan
Published: March 2020

Lanzhou lies at the western Loess Plateau, China, and has a typical semi-arid temperate continental climate. Plants in this area are exposed to a prolonged dry season. In this study, we measured the stable isotopes of hydrogen (δD) and oxygen (δ18O) of the local precipitation, river water, soil water, plant xylem water, and leaf water at four sampling sites during the 2016 growing season. Our results showed that plants relied mostly on wet season precipitation at sites N1, N2, and N3 because this recharged the soil after the long dry season. Leaf phenology had a significant effect on evaporation distance (ED) value, and evergreen plants have adapted to water tapping from deep soil water sources during the dry season. The ED values of trees and shrubs were quite different in the dry season, indicating water competition among different plant species was mitigated due to water resource partitioning. Moreover, plants at site N4 relied on a water source admixed with river water throughout the whole growing season. The mean value of xylem-to-leaf water deuterium enrichment (ɛl/x) was −0.91 ± 0.36‰ over all plant species, seasons, and sampling sites. Plant species, leaf phenology, and seasons were found to be the primary factors influencing the ɛl/x, while growth form and elevation had negligible effects.
Fate and behaviour of acetaminophen, 17α-ethynylestradiol and carbamazepine in aqueous solution
Authors: Santos Albano Joel Moreira , Cardoso Cláudia Sofia Gomes , Mota Albertina Alice Ribeiro , Belmonte Patrícia Raquel Heleno , Oliveira Manuel António Campo Grande , da Silva Joaquim Carlos Gomes Esteves
Published: March 2020

Pharmaceuticals are invaluable tools for the prevention and treatment of human and animal diseases. Human evolution led to the increase of life expectancy, which promoted the increase of consumption of pharmaceuticals. These compounds are consistently detected in superficial waters, and whilst degradation processes are expected to mitigate their levels, they also induce the formation of potentially harmful by-products. The compounds studied in this work were acetaminophen, 17α-ethynylestradiol and carbamazepine. High-performance liquid chromatography coupled with ultraviolet diode-array detection was used to follow the degradation reactions, whilst liquid chromatography associated with ultraviolet diode-array detection and mass spectrometry was applied in the determination of by-products. Ethynylestradiol proved to be the most reactive (t1/2 = 38.6 ± 1.9 seconds) and carbamazepine the least reactive (t1/2 = 481.4 ± 16.7 minutes) when exposed to active chlorine. In relation to disinfection by-products, two monochlorinated analogues were detected for acetaminophen, one monochlorinated for carbamazepine, and one mono- and one trichlorinated for ethynylestradiol. Chlorine levels and water pH proved to be the most influential variables on the degradation of the compounds, with and without dissolved organic matter in solution. All pharmaceuticals displayed significant photostability towards artificial solar radiation, with acetaminophen being slightly more stable.
FORRÓ: ENTRE CONSUMO E TRADIÇÃO NO MUNDO CONTEMPORÂNEO
Authors: Paulino Thiago
Published: March 2020

Nos processos identitários, músicos e consumidores formam redes de interdependência como aliados ou adversários em diferentes níveis de poder.  Este artigo pretende promover uma reflexão de como a produção musical comporta múltiplos pertencimentos situado entre a tradição e a modernização. Essa dinâmica acentua-se na atual globalização que facilita intercâmbios culturais capazes de gerar violência, mas também uma atitude dialógica intercultural enriquecedora. O forró como demais bens culturais se insere na lógica do mercado em busca do lucro e transforma espaços e relações humanas através do consumo. Enquanto bem de consumo, modalidades do forró tem como uma das características o descarte de músicas de sucesso e sua substituição por novidades. Este forró produzido pelo mercado do entretenimento e veiculado pela grande mídia exerce grande influência na formação de repertório de atores sociais aos quais é negada a música de qualidade. À alta rotatividade dos produtos de consumo opõe-se à criação artística mais elaborada que necessita de tempo para projetar, produzir, reformular e amadurecer. Essa situação se agrava quando a educação perde seu caráter formador e informador para uma consciência mais crítica e uma ação mais construtiva.
IDENTIDADE CULTURAL SOB UMA PERSPECTIVA FÍLMICA: CINEMA E INTERDISCIPLINARIDADE
Authors: Valvano Thaís
Published: March 2020

Este trabalho tem como objetivo investigar a utilização do cinema como fonte histórica. Para tanto, resgata o caráter interdisciplinar que a análise fílmica possibilita, buscando novos instrumentos de interpretação social. Sob essa perspectiva, a pesquisa encarrega-se de interpretar o modo como a cultura rural foi representada a partir da produção fílmica de Mazzaropi. Desse modo, abre-se um leque de possibilidades investigativas, visto que nesses filmes temas como identidade; migração; dicotomia entre campo/ cidade e relação entre tradição/ modernidade são recorrentes. Além disso, o trabalho não se limita à interpretação fílmica apenas, mas também nas críticas especializadas e na bibliografia.
The Influence of Ca2+ and Zn2+ on the Amyloid Fibril Formation by β-Casein
Authors: Wang Jia , Liu Jihua , Du Guangguang , An Yang , Zhao Chunfang , Zeng Baohua
Published: March 2020

Background:

The amyloid fibril formation in different tissues or organs is related to
amyloidosis. The Ca2+, Zn2+ and heparan sulfate (HS) are important elements and compositions in
human body, which play a key role in regulating various physiological activities. Recently, there
are increasing evidence suggest that they are closely linked to the amyloid fibril formation.

Objective:

The effect of Ca2+ and Zn2+ on the amyloid fibril formation by β-casein was investigated
in the absence and presence of HS, which was significantly to explore the relationship between the
concentration changes of Ca2+ and Zn2+ and amyloid fibril formation.

Method:

In this work, the influence of Ca2+ and Zn2+ on the β-casein fibril formation in the
absence and presence of HS was investigated by various methods of Thioflavin T fluorescence assay,
transmission electron microscopy and intrinsic fluorescence measure.

Results:

The results demonstrated that Ca2+ and Zn2+ promoted the β-casein fibril formation. The effect
of Ca2+ was greater than that of Zn2+. Meanwhile, the both metal ions had stronger effects when
β-casein was incubated with HS together. In addition, it was also observed that the microenvironment
of β-casein was changed because the intrinsic fluorescence peaks were red-shifted on the influence
of Ca2+ and Zn2+.

Conclusion:

Ca2+ and Zn2+ were capable of promoting the β-casein fibril formation in the both
absence and presence of HS. This work set up the foundation for further researching of the amyloidosis
pathogenesis and provided new insight for us to understand relationship between the inflammation
and amyloidosis.
Anticancer Potential of Calli Versus Seedling Extracts Derived from Rosmarinus officinalis and Coleus hybridus
Authors: Albogami Sarah , Darwish Hadeer , Abdelmigid Hala M. , Alotaibi Saqer , El-Deen Ahmed Nour , Alnefaie Alaa , Alattas Afnan
Published: March 2020

Background:

In Saudi Arabia, the incidence and mortality rates of breast cancer are high.
Although current treatments are effective, breast cancer cells develop resistance to these treatments.
Numerous studies have demonstrated that active compounds in plant extracts, such as the phenolic
compound Rosmarinic Acid (RA), exert anti-cancer effects.

Objective:

We investigated the anticancer properties of methanolic crude extracts of seedlings and calli
of Rosmarinus officinalis and Coleus hybridus, two Lamiaceae species.

Methods:

MCF-7 human breast cancer cells were treated with methanolic crude extracts obtained from
plant calli and seedlings generated in vitro, and cell proliferation was evaluated. Transcriptional profiling
of the seedling and callus tissues was also conducted.

Results:

The mRNA expression levels of RA genes were higher in C. hybridus seedlings than in R. officinalis
seedlings, as well as in C. hybridus calli than in R. officinalis calli, except for TAT and C4H.
In addition, seedling and callus extracts of both R. officinalis and C. hybridus showed anti-proliferative
effects against MCF-7 cells after 24 or 48 h of treatment.

Discussion:

At a low concentration of 10 μg/mL, C. hybridus calli and seedling extracts showed the most
significant anti-proliferative effects after 24 and 48 h of exposure (p < 0.01); controls (doxorubicin) also
showed significant inhibition, but lesser than that observed with C. hybridus (p < 0.05). Results with R.
officinalis callus and seedling extracts did not significantly differ from those with untreated cells.

Conclusion:

Methanolic extracts of R. officinalis and C. hybridus are potentially valuable options for
breast cancer treatment.
Protein Histidine Methylation
Authors: Kwiatkowski Sebastian , Drozak Jakub
Published: March 2020

Protein histidine methylation is a rarely studied posttranslational modification in eukaryotes.
Although the presence of N-methylhistidine was demonstrated in actin in the early 1960s, so far, only a
limited number of proteins containing N-methylhistidine have been reported, including S100A9, myosin,
skeletal muscle myosin light chain kinase (MLCK 2), and ribosomal protein Rpl3. Furthermore,
the role of histidine methylation in the functioning of the protein and in cell physiology remains unclear
due to a shortage of studies focusing on this topic. However, the molecular identification of the
first two distinct histidine-specific protein methyltransferases has been established in yeast (Hpm1) and
in metazoan species (actin-histidine N-methyltransferase), giving new insights into the phenomenon of
protein methylation at histidine sites. As a result, we are now beginning to recognize protein histidine
methylation as an important regulatory mechanism of protein functioning whose loss may have deleterious
consequences in both cells and in organisms. In this review, we aim to summarize the recent
advances in the understanding of the chemical, enzymological, and physiological aspects of protein
histidine methylation.
Non-Alcoholic Fatty Liver Disease and Vascular Disease
Authors: Forlano Roberta , Mullish Benjamin H. , Nathwani Rooshi , Dhar Ameet , Thursz Mark R. , Manousou Pinelopi
Published: March 2020

Non-Alcoholic Fatty Liver Disease (NAFLD) represents an increasing cause of liver disease
worldwide. However, notably, the primary cause of morbidity and mortality in patients with NAFLD is
cardiovascular disease (CVD), with fibrosis stage being the strongest disease-specific predictor. It is
globally projected that NAFLD will become increasingly prevalent, especially among children and
younger adults. As such, even within the next few years, NAFLD will contribute considerably to the
overall CVD burden.
In this review, we discuss the role of NAFLD as an emerging risk factor for CVD. In particular, this
article aims to provide an overview of pathological drivers of vascular damage in patients with NAFLD.
Moreover, the impact of NAFLD on the development, severity and the progression of subclinical and
clinical CVD will be discussed. Finally, the review illustrates current and potential future perspectives
to screen for CVD in this high-risk population.
The Multicenter Italian Trial Assesses the Performance of FDG-PET /CT Related to Pre-Test Cancer Risk in Patients with Solitary Pulmonary Nodules and Introduces a Segmental Thoracic Diagnostic Strategy
Authors: Spadafora Marco , Evangelista Laura , Fiordoro Salvatore , Porcaro Francesco , Sicignano Marilena , Mansi Luigi
Published: March 2020

Purpose:

The Italian Tailored Assessment of Lung Indeterminate Accidental Nodule (ITALIAN)
trial is a trial drawn to determine the performance of 18F-FDG-PET/CT in patients with solitary
pulmonary nodules (SPN), stratified for a different kind of risk. An additional end-point was to compare
the diagnostic information and estimated dosimetry, provided by a segmental PET/CT (s-PET/CT)
acquisition instead of a whole body PET/CT (wb-PET/CT), in order to evaluate if segmental thoracic
PET/CT can be used in patients with SPN.

Methods:

18F-FDG PET/CT of 502 patients, stratified for pre-test cancer risk, was retrospectively
analyzed. FDG uptake in SPN was assessed by a 4-point scoring (4PS) system and a semiquantitative
analysis using the ratio between SUVmax in SPN and SUVmean in mediastinal blood pool (BP), and
between SUVmax in SPN and SUVmean in the liver (L). Histopathology and/or follow-up data were
used as a standard of reference. Data obtained on the thoracic part of wb-PET/CT, defined as s -
PET/CT, were compared with those deriving from wb-PET/CT.

Results:

SPNs were malignant in 180 patients (36%), benign in 175 (35%), and indeterminate in 147
(29%). The 355 patients diagnosed with a definitive SPN nature (malignant or benign) were considered
for the analysis of PET performance. Sensitivity, specificity, positive (PPV) and negative (NPV) predictive
values, and accuracy were 85.6%, 85.7%, 86%, 85.2%, and 85.6%, respectively. Sensitivity and
PPV were higher in intermediate and high-risk patients.

18F-FDG uptake indicative of thoracic and extra-thoracic lesions was detectable in 13% and 3% of the
patients. Compared to wb-PET/CT, s-PET/CT could save about 2/3 of 18F-FDG dose, radiation exposure
or scan-time, without affecting the clinical impact of PET/CT.

Conclusion:

In patients with SPN, the pre-test likelihood of malignancy stratification allows to better
define PET clinical setting and its diagnostic power. In subjects with low-intermediate pre-test likelihood
of malignancy, s-PET/CT might be planned in advance. The adoption of this segmental strategy
could reduce radiation exposure, scan-time, and might allow individually targeted protocols.
The growing interest in vitamin D is positively related to that of its kidney complications and is negatively related to that of bone benefit: an analysis based on Google Trends (Preprint)
Authors: Zaffanello Marco
Published: March 2020

BACKGROUND

The benefits of vitamin D relate to muscle strength, cardiovascular health, and prevents osteoporosis.

OBJECTIVE

This study aimed to explore trends of global interest on vitamin D, hypercalcaemia, adverse kidney effects (stones and kidney failure) and osteoporosis

METHODS

An electronic search was conducted with Google Trends, limiting searches based on the "health" criterion.

RESULTS

Worldwide interest in vitamin D3 (cholecalciferol), vitamin D2 (ergocalciferol or calciferol), kidney stones and kidney failure is progressively growing over time. On the other hand, vitamin D was found to be negatively correlated with hypercalcaemia and bone density. Another result of our analysis is the distribution of the popularity of searches across countries. In particular, the global popularity for vitamin D3 seems higher than that of vitamin D2 and also shows different geographical preferences. The growing interest in vitamin D parallels that of kidney stones and kidney failure, while decreasing popularity has been noted for hypercalcaemia and bone density

CONCLUSIONS

The research volumes help to clarify the changes in the trends of use of supplements and the development of their complications, according to the different geographical areas, socio-economic status and online literacy
Patient Challenges and Needs in Comprehending Laboratory Test Results: Mixed Methods Study (Preprint)
Authors: Zhang Zhan , Citardi Daniel , Xing Aiwen , Luo Xiao , Lu Yu , He Zhe
Published: March 2020

BACKGROUND

Patients are increasingly able to access their laboratory test results via patient portals. However, merely providing access does not guarantee comprehension. Patients could experience confusion when reviewing their test results.

OBJECTIVE

The aim of this study is to examine the challenges and needs of patients when comprehending laboratory test results.

METHODS

We conducted a web-based survey with 203 participants and a set of semistructured interviews with 13 participants. We assessed patients’ perceived challenges and needs (both informational and technological needs) when they attempted to comprehend test results, factors associated with patients’ perceptions, and strategies for improving the design of patient portals to communicate laboratory test results more effectively. Descriptive and correlation analysis and thematic analysis were used to analyze the survey and interview data, respectively.

RESULTS

Patients face a variety of challenges and confusion when reviewing laboratory test results. To better comprehend laboratory results, patients need different types of information, which are grouped into 2 categories—generic information (eg, reference range) and personalized or contextual information (eg, treatment options, prognosis, what to do or ask next). We also found that several intrinsic factors (eg, laboratory result normality, health literacy, and technology proficiency) significantly impact people’s perceptions of using portals to view and interpret laboratory results. The desired enhancements of patient portals include providing timely explanations and educational resources (eg, a health encyclopedia), increasing usability and accessibility, and incorporating artificial intelligence–based technology to provide personalized recommendations.

CONCLUSIONS

Patients face significant challenges in interpreting the meaning of laboratory test results. Designers and developers of patient portals should employ user-centered approaches to improve the design of patient portals to present information in a more meaningful way.
Smartphone-based app for Carpal tunnel syndrome testing - primary study. (Preprint)
Authors: Szklener Sebastian , Szklener Katarzyna , Rejdak Konrad
Published: March 2020

BACKGROUND

Carpal tunnel syndrome (CTS) occurs in as many as 3% of the population. This common condition should be diagnosed earlier because delays in treatment can lead to the loss of some hand functions. Delays are caused in a substantial part by the patients themselves, therefore there is a need to have a screening tool for them – especially in the era of telemedicine. Such a screening tool should have the necessary features: should be easy to use , simple to interpret, universally available and with high sensitivity and specificity values.

OBJECTIVE

To establish the diagnostic value of a new screening tool for CTS – smartphone based tapping test.

METHODS

The database included each patient who reported himself to the local clinic with suspected CTS. The diagnosis of CTS was made by neurologists based on electrophysiological testing. The Studied population was divided into two groups, positive-CTS and negative-CTS. Patients were asked to perform 60 seconds “tapping” a test on a smartphone-based app. The selected parameters of thumb movements were recorded by the app and compered between each group.

RESULTS

The criteria for inclusion in this study were met by 38 patients (24 positive-CTS and 14 negative-CTS). Mean finger-to-screen contact duration was longer (144 vs. 107 ms; P<.0001), mean click frequency was lower(3.7 vs. 4.3 Hz; P<.0001) and mean deviation from the center of the circle was greater(14.125 vs. 14.07 pix; P<.0001).In multivariate analysis, only the mean thumb-to-screen contact time was statistically significant (P=.03). The ROC curve for this variable showed high sensitivity (75%) and specificity (86%).

CONCLUSIONS

Tapping test parameters significantly correlate with diagnosis of CTS. The collected results allowed us to create the prototype of the next screening tool for CTS. The test is easy to perform (tapping on a screen), simple to interprete (do not need subjective interpretation), universally available (carpaltunnel-test.com) and to have high sensitivity and specificity values.

CLINICALTRIAL
What’s in a Face? Gender representation of faces in Time, 1940s-1990s
Authors: Jofre Ana , Cole Josh , Berardi Vincent , Bennett Carl , Reale Michael
Published: March 2020

We extracted 327,322 faces from an archive of Time magazine containing 3,389 issues dating from 1923 to 2014, classified the gender of each extracted face, and discovered that the proportion of female faces contained within this archive varied in interesting ways over time. The proportion of female faces first peaked in the mid-to-late 1940s. This was followed by a dip lasting from the mid-1950s to the early 1960s. The 1970s saw another peak followed by a dip over the course of the 1980s. Finally, we see a slow and steady rise in the proportion of female faces from the early 1990s onwards. In this paper, we seek to make sense of these variations through an interdisciplinary framework drawing on psychology, visual studies (in particular, photography theory), and history. Through a close reading of our Time archive from the 1940s through the 1990s, we conclude that the visual representation of women in Time magazine correlates with attitudes toward women in both the historical context of the era and the textual content of the magazine.
La identidad y lo subjetivo: experiencia y vida en la sociología de las emociones
Authors: Fowks Jacqueline
Published: March 2020

La identidad y lo subjetivo: experiencia y vida en la sociología de las emociones
¿Por qué la dificultad de ser?
Authors: Torres Arias María Antonieta
Published: March 2020

¿Por qué la dificultad de ser?
Las metáforas del cuerpo
Authors: García Canal María Inés
Published: March 2020

Las metáforas del cuerpo
Editorial
Authors: Feminista Debate
Published: March 2020

Editorial
Alejandra revisited
Authors: De Cicco Gabriela
Published: March 2020

Alejandra revisited
Pavana para una infanta difunta
Authors: Orozco Olga
Published: March 2020

Pavana para una infanta difunta
La autobiografía femenina: ¿un género diferente?
Authors: Araújo Nara
Published: March 2020

La autobiografía femenina: ¿un género diferente?
Las tram(p)as del feminismo chileno de hoy
Authors: Autor Sin
Published: March 2020

Las tram(p)as del feminismo chileno de hoy
Articulaciones y desarticulaciones de las feministas hoy
Authors: Valdés Alejandra
Published: March 2020

Articulaciones y desarticulaciones de las feministas hoy
El incesto: hacer "con" las mujeres
Authors: Leclaire Serge , Vericat Isabel
Published: March 2020

El incesto: hacer  las mujeres
Por qué
Authors: Venier Martha Elena
Published: March 2020

Por qué 
El feo encuentro de la necesidad
Authors: Gargallo Francesca
Published: March 2020

El feo encuentro de la necesidad
Vivencias del encuentro de Chile: lo personal y lo político
Authors: Birgin Haydeé B.
Published: March 2020

Vivencias del encuentro de Chile: lo personal y lo político
Leonora Carrington en sus ochenta: la creación compartida
Authors: Domenella Ana Rosa
Published: March 2020

Leonora Carrington en sus ochenta: la creación compartida
Dialéctica feminista de la ilustración
Authors: Rojo Arias María Del Pilar
Published: March 2020

Dialéctica feminista de la ilustración
A propósito de una ciencia más justa
Authors: Mendiola Salvador
Published: March 2020

A propósito de una ciencia más justa
La mano que mece el pesebre
Authors: Usabiaga Luis , Rodríguez Jesusa
Published: March 2020

La mano que mece el pesebre
Los que tenemos unas manos que no nos pertenecen: (a propósito de lo  y lo )
Authors: Monsiváis Carlos
Published: March 2020

Los que tenemos unas manos que no nos pertenecen: (a propósito de lo  y lo )