bluuebunny/crossref_metadata_2025 huggingface dataset:
Kegiatan Pengembangan Kognitif Anak Usia Dini di Taman Kanak-kanak Negeri Pembina Painan
Authors: Hersi Nadia , Yulsyofriend Yulsyofriend
Published: March 2022

Penelitian ini ditujukan dalam mendeskripsikan tentang kegiatan pengembangan kognitif anak usia dini. Jenis penelitian ini memakai penelitian deskriptif kualitatif. Data dikumpulkan melalui kegiatan observasi, kegiatan wawancara serta diperlukan adanya dokumentasi. Sementara itu dalam menganalisis data, dikumpulkan untuk selanjutnya direduksi dan disajikan, serta diakhiri dengan penarikan kesimpulan. Teknik keabsahan data menggunakan teknik triangulasi. Hasil penelitian ini mencakup perencanaan dalam kegiatan pengembangan kognitf anak usia dini berpedoman pada tema, sub tema, serta indikator yang dirancang sebelum tahun ajaran. Pelaksanaan kegiatan di semua sentra dapat mengembangkan kemampuan kognitif anak. Evaluasi kegiatan pengembangan kognitif dilakukan melalui observasi, dan menuangkan dalam bentuk teknik penilaian; ceklis, unjuk kerja, catatan hasil karya, dan anekdot.
EMERGENCE OF THE ISTANBUL ART NOUVEAU STYLE OF RAIMONDO D ARONCO: THE TRANSFORMATION FROM THE SCHOOL OF INDUSTRY TO THE MINISTRY OF FORESTRY, MINING AND AGRICULTURE AND THE JANISSARY MUSEUM
Authors: KULELİ Ayşe Esin , PFEIFFER TAŞ Şule
Published: March 2022

This study details the transformation of the Istanbul School of Industry (Dersaadet Sanayi Mektebi) building at the Sultan Ahmed Square which was originally built between 1866 and 1868, and now serves as the Marmara University Rectorate Building. Because of the damage caused by the great earthquake of 1894, the building was redesigned by Raimondo D’Aronco between 1894 and 1900 for use as the Ministry of Forestry, Mining and Agriculture, and the Janissary Museum was added to the building. The authors believe that this design is one of the first interpretations of the Art Nouveau movement in Istanbul and reflects its first traces in the Ottoman Empire as genius loci, although it was also interpreted differently by other experts. As known, the Istanbul Art Nouveau later became very popular, especially in residential construction. The present study discusses how the Ottoman local architectural tradition is reflected in Raimondo D’Aronco’s design together with the elements of the Art Nouveau in this building. Since the building is one of the earliest works by D’Aronco reflecting precise dates in this style, it gives us the opportunity to follow the development of his art as well. The drawings of the facade, digitally documented by using a 3D Laser scanner for the first time, additionally provide information on the construction phases as supported by researches.
YAVUZ SULTAN SELİM İN MISIR SEFERİNDE ŞAM KALESİ NDE ELDE EDİLEN EŞYALAR
Authors: İNBAŞI Mehmet
Published: March 2022

24 Ağustos 1516’da Mercidabık’ta Memlük ordusunu mağlup eden Yavuz Sultan Selim, 28 Ağustos’ta Halep’e girmiş ve 15 Eylül’e kadar burada kaldıktan sonra Halep valiliğine Karaca Paşa’yı, Halep kadılığına da Kemal Çelebi’yi tayin ettikten sonra Şam tarafına harekete geçmişti. Halep Kalesi’nde elde edilen kitapların tespiti yapılarak İstanbul’a gönderilmişti. Bu kitaplarla ilgili bir çalışma tarafımızdan yapılmıştı. Osmanlı ordusu Hama ve Hums üzerinden Şam’a gelmiş ve şehir aman ile teslim olmuştur. Padişah Şam’ın dışında Mastaba denilen yerde otağını kurdurmuş ve 12 gün burada kaldıktan sonra 9 Ekim 1516’da Şam’a girmiştir. Osmanlı ordusu ve padişah 28 Eylül’den 16 Aralık tarihine kadar yaklaşık 80 gün Şam’da kalmıştır. Bu süre içinde gerekli hazırlıklar ve idari düzenlemeler yapılmış, daha sonra da Mısır seferine çıkılmıştır. Yavuz Sultan Selim Şam’a girdikten sonra Şam Kalesi’nde bulunan eşyalar tespit edilmiş ve bununla ilgili olarak bir defter hazırlanmıştı. Defter-i oldur ki Şam Kal‘ası'nda mevcud bulunan bunlardır ki zikr olunur başlığı ile verilen defterde kaleden elde edilen hazine ve çeşitli eşyaların isimleri ile bunların kıymetleri belirtilmiştir. Bu çalışmada Şam Kalesi’nde tespit edilen hazine ve eşyalar hakkında bilgi verilecek ve bunların hangi kalemlerden oluştuğu Cumhurbaşkanlığı Osmanlı Arşivi’nde bulunan belgelere göre ortaya konulacaktır.
Tele-rehabilitation of a middle-aged female with bronchiectasis as post COVID-19 sequelae: a case report
Authors: V. Verma Chhaya , Kamble Rutuja
Published: March 2022

COVID-19 pneumonia causes dilatation of lung parenchyma which leads to destruction of segmental bronchi that can further progress into bronchiectasis. COVID-19 causes many sequels in the respiratory system and frequently presents with dyspnoea, fatigue, loss of strength, reduced functional capacity and sometimes severe multi-organ affection. Physiotherapy interventions through tele-rehabilitation have acquired a fundamental role in the recovery of the functions and quality of life. Pulmonary tele-rehabilitation which is done in this case report study includes patient education, respiratory care, exercise training, ambulatory program with supplementary oxygen, strengthening, endurance training and energy conservation. All these interventions play an important role in patent’s treatment protocol from hospital discharge to resuming work by assisting in weaning of supplementary oxygen, improving functional capacity of lungs and thus facilitating recovery. Rehabilitation of COVID-19 causing bronchiectasis in healthy individual has not been reported in literature yet. So, here we present a case report of tele-rehabilitation of a middle- aged female who developed progressive bronchiectasis as a sequela of COVID-19 pneumonia evident on serial chest CT scans.
Nigam’s scoring system for acute appendicitis with high accuracy surpassing Alvarado scoring system
Authors: Nigam Vinod Kumar , Nigam Siddarth
Published: March 2022

Background: Acute appendicitis is one of the most common surgical emergencies. Delay in the treatment of acute appendicitis can result in complications, may be lethal. That’s why the early diagnosis and quick treatment is essential. The diagnosis of acute appendicitis is still a clinical one. Alvarado scoring system is the commonest scoring system but it has many lacunae. Nigam’s scoring system (NSS) is invented to deal with drawbacks of Alvarado scoring system and improve accuracy.Methods: NSS has 17 scoring points. This scoring system can be divided into three parts, 6 and below 6, 7 to 10, and 11 and above. This study includes 36 patients of acute abdomen during a period of 8 years from Jan 2012 to Jan 2020. The diagnosis of acute appendicitis by NSS was compared with the ultrasonography findings, operation findings, and histopathological results.Results: Out of 36 patients 2 patients scored 6 and below, 3 patients scored 7 to 10 and 31 patients scored 11 and above. Accuracy of NSS resulted in 100%. No negative appendicectomy was recorded.Conclusions: NSS has better accuracy than Alvarado scoring system in diagnosing acute appendicitis. NSS is an easy, economical, simple, accurate, fast and dependable scoring system. NSS is best suited for small hospitals which lack advance investigative techniques such as ultrasound, CT scan and MRI.
Czy władza jest wszędzie? Krytyka dwóch uzasadnień Foucaultowskiej tezy o powszechności władzy
Authors: Stachowiak Jerzy
Published: March 2022

Michel Foucault jest jednym z tych autorów, którzy istotnie przysłużyli się do poszerzenia znaczenia terminu „władza” oraz obszarów, w których szuka się jej przejawów. Wkład Foucaulta w rozbudowę studiów nad władzą jest jednak frapujący. Otóż w Historii seksualności Foucault zaczął otwarcie przekonywać, że władza jest po prostu wszędzie. Ten pogląd – teza o powszechności władzy – ma u Foucaulta dwa, rozwijane latami, uzasadnienia. Na użytek niniejszej analizy pierwsze z nich zyska nazwę uzasadnienia historiozoficznego, a drugie – uzasadnienia zróżnicowaniem społecznym. Celem artykułu jest krytyka ich obu, a pośrednio także tezy, którą wspierają. Ich rekonstrukcja i krytyczne rozpatrzenie są ważne dla postfoucaultowskiego nurtu w naukach społecznych, ponieważ ramy wszelkiej Foucaultowskiej analityki władzy wyznaczone są właśnie przez te dwa uzasadnienia.
Islamic Philosophy and Ethics of Education: Al- Zarnūjī’s Concept of Taʻẓīm in his Ta‘līm al-Muta‘allim
Authors: Huda Miftachul
Published: March 2022

Respect has demonstrated psychological, social and academic benefits; however, it has been a lack from attention for most researchers in promoting character development for the student. This article aims to critically explore respect as a moral concept and explain how respect can contribute to current discussions in developing character education, mainly from the perspective of one of the classical Muslim scholar, al-Zarnūjī, based on his esteem work on the concept of Ta‘līm al-Muta‘allim, as one of the references in learning and teaching guidelines among Islamic boarding school (pesantren) in Indonesia. Critical review from referred journal and book was conducted to the contributions in the domain of character education. There are three main discussions as the result of this study. First, it is respect to the knowledge as a light of understanding. Second, it is respect to the teacher as the most role model and actor of knowledge sharing; and third it is respect to the colleague as partner in learning process. Thus, respect in its three dimensional aspects should govern the learning and teaching process.
Sağlık Çalışanlarının Bilgi Güvenliği Farkındalığının İş Performansı Üzerindeki Etkisinde Bilgi Güvenliği Stresinin Aracı Rolü: Covid 19 Pandemi Döneminde Bir Araştırma (Mediator Role of Information Security Stress in the Effect of Information Security Awareness of Health Personnel on Job Performance: A Research in Covid-19 Pandemic Period)
Authors: Gün İsmail , Çelik Mazlum
Published: March 2022

Amaç – COVID 19 döneminde iş yaşamında teknolojinin daha yoğun şekilde kullanılmasından ötürü, bu süreçte çalışanlar nezdinde bilgi güvenliğine ilişkin konuların önemi artış göstermiştir. Bu araştırmanın amacı, COVID 19 pandemisi döneminde sağlık çalışanlarında bilgi güvenliği farkındalığının iş performansı üzerindeki etkisini ölçmek ve bu etkide bilgi güvenliği stresinin aracı rolünün bulunup bulunmadığını araştırmaktır. Yöntem – Örneklem olarak, Mardin Devlet Hastanesi sağlık personeli seçilmiştir. Nicel araştırma yönteminin uygulandığı bu çalışmada, açıklayıcı araştırma tekniğinden yararlanılmış ve veri toplamak üzere anket tekniği kullanılmıştır. Bilgi güvenliği farkındalığı için Keser ve Güldüren (2015) tarafından geliştirilen 34 maddelik ölçek, iş performansı için Kirkman ve Rosen (1999) tarafından geliştirilip Çöl (2008) tarafından Türkçe uyarlaması yapılan 4 maddelik ölçek, bilgi güvenliği stresi için Ayyagari, Grover ve Purvis (2011) tarafından geliştirilen 8 maddelik ölçek kullanılmıştır. Toplanan veriler SPSS-23 programı aracılığıyla analiz edilmiştir. Analiz için faktör analizi, güvenilirlik analizi, korelasyon analizi ve regresyon analizi kullanılmıştır. Bulgular – Araştırmada, sağlık çalışanlarında bilgi güvenliği farkındalığının iş performansı üzerinde pozitif ve anlamlı etkiye sahip olduğu ve bu etkide bilgi güvenliği stresinin kısmi aracılık rolünün olduğu bulgularına erişilmiştir. Tartışma – Bilgi güvenliği farkındalığının iş performansı üzerinde anlamlı etkisi olduğuna ilişkin bulgunun, bilgi güvenliği farkındalığının bilgi güvenliği stresi üzerinde anlamlı etkiye sahip olduğuna ilişkin bulgunun, bilgi güvenliği stresinin iş performansı üzerinde anlamlı etkiye sahip olduğuna ilişkin bulgunun, bilgi güvenliği farkındalığının iş performansı üzerindeki etkisinde bilgi güvenliği stresinin kısmi aracı rolünün olduğuna ilişkin bulgunun, literatürdeki önceki çalışmaların bulgularıyla paralel olduğu tespit edilmiştir.
Rol İçi ve Rol Dışı Performansta İş Taleplerinin ve İş Kaynaklarının Etkisinde Psikolojik Sözleşmenin Aracı Rolü (The Mediating Role of The Psychological Contract in the Effect of Job Demands and Job Reseources on in Role and Extra Role Performance)
Authors: Doğan Selen , Şeker Kayar Mehtap
Published: March 2022

maç –Bu çalışmanın amacı, rol içi ve rol dışı performansta iş talepleri ve iş kaynaklarının etkisinde psikolojik sözleşmenin aracılık rolü olup olmadığını ortaya çıkarmaktır.Yöntem –Araştırmanın evrenini, Kayseri’de faaliyet gösteren mobilya ve bilişim sektöründe yer alan işletmelerdeki çalışanlar oluşturmaktadır. Araştırma verilerini elde etmek üzere zaman ve ekonomik açıdan tasarruf etmek amacıyla çalışanlara basit tesadüfü örnekleme yöntemi kullanılarak anket uygulanmış ve araştırmanın örneklemini 528 katılımcı oluşturmuştur. Anket çalışmasında elde edilen veriler istatistiksel analiz programı ile geçerlilik, güvenilirlik, korelasyon analizi ve aracı etki analizleri yapılarak değerlendirilmiş ve yorumlanmıştır.Bulgular –Araştırmada işlemsel ve ilişkisel psikolojik sözleşme ile iş talepleri ve iş kaynakları arasında pozitif yönlü bir ilişki olduğu tespit edilmiştir. Ayrıca işlemsel sözleşme ile bağlamsal performans arasındaki ilişkinin pozitif yönlü olduğu fakat ilişkisel sözleşme ile görev performansı arasındaki ilişkinin ise negatif yönlü olduğu görülmektedir. Araştırmada aracı etki etki analizi sonuçlarına göre ise iş talepleri alt boyutlarından duygusal talepler ile bağlamsal (rol dışı)performans ilişkisinde işlemsel ve ilişkisel psikolojik sözleşmenin aracı rolü bulunmaktadır. İş taleplerinden iş yükü ile bağlamsal performans ilişkisinde ve iş kaynakları alt boyutlarından otonom çalışma ve mesleki gelişim imkânları ile bağlamsal performans ilişkisinde de işlemsel sözleşmenin aracı rolü olduğu ortaya çıkmıştır. Tartışma –Bu çalışma, iş talepleri ve iş kaynakları ile görev ve bağlamsal performans arasında pozitif yönlü bir ilişki olduğunu ve bu ilişkide işlemselpsikolojik sözleşmenin olumlu yönde aracılık rolü üstlendiğini ortaya koymaktadır. Bu bağlamda yapılan çalışma ile örgüt-çalışan ilişkilerinde ve çalışan performansı konusunda psikolojik sözleşme ile ulusal alanda çok az sayıda çalışmada ele alınan iş talepleri ve iş kaynaklarının etkilerine vurgu yapılmaktadır.
Sigorta Harcamaları ve Gayri Safi Yurt İçi Hasıla Değişkenlerinin Sigorta Pazar Payına Etkisi (Insurance Expenditures and Gross Domestic Product Variables Effect on Insurance Market Share)
Authors: Dalkılıç Nilüfer , Gülcemal Merve Esra
Published: March 2022

Amaç –Sigortacılık sektörü oluşturduğu fon itibariyle ve risk transfer sistemi ile ekonomide en önemli sektörlerden bir tanesidir. Sigortacılık sektörü ekonominin gelişimiyle ve tüketimle oldukça ilişkili bir yapıya sahiptir. Çalışmanın amacı Türkiye’nin 1990-2019 yıllarında sigorta harcamaları ve gayri safi yurt içi hasılasının sigorta pazar payına etkisini araştırmaktır.Yöntem –Çalışmada eşbütünleşik regresyon analizi yapılarak; dinamik en küçük kareler, tam değiştirilmiş en küçük kareler ve kanonik eşbütünleşik regresyon modelleri yardımı ile eşbütünleşme katsayıları bulunmuştur. Bu sayede değişkenler arasındaki ilişkinin yönü tespit edilmiştir.Bulgular –Çalışmada Türkiye’de 1990 –2019 yıllarında gayri safi yurt içi hasıla ve sigorta harcamalarında yaşanan artışın, sigorta pazar payını olumluyönde etkilediği ve sigorta pazar payının artmasına katkı sağladığı sonucuna ulaşılmıştır.Tartışma –Elde edilen her üç eşbütünleşik regresyon modelinin birbirine çok yakın sonuçlar verdiği ve üç modelin sonuçlarının birbiri ile örtüştüğü sonucuna ulaşılmıştır.Gayri Safi Yurtiçi Hasıla’nın arttırılmasına yönelik yapılacak çalışmalar, sigorta pazar payının ve sigorta harcamalarının artmasına da katkı sağlayacaktır. Sigorta harcamalarının arttırılmasına yönelik yapılacak çalışmalar da sigorta pazar payının artmasına katkı sağlayacaktır.
İş Ahlakı Uygulamalarının Örgütsel Performansa Etkisi: Özel Hastaneler Üzerine Bir Saha Araştırması(The Influence of Business Ethics Practices on Organizational Performance: A Field Research on Private Hospitals)
Authors: Ertaş Abdulkadir , Orhan Mehmet
Published: March 2022

Amaç –Sağlık sektörü, ahlaki ilke ve kurallara en çok ihtiyaç duyulan sektörlerden biridir. Bu çalışma, hastanelerde iş ahlakı uygulamalarının örgütsel performansı nasıl ve ne yönde etkilediğini belirlemek amacıyla yapılmıştır.Yöntem –Bu çalışmada iş ahlakı; yöneticilerin ahlaki tutumları, çalışanların ahlaki tutumları ve hastanelerin ahlaki tutumları olmak üzere üç boyutta ele alınmış ve saha araştırması yapılmıştır. Veriler İstanbul’da özel hastanelerde çalışandoktor, hemşire ve diğer sağlık personellerinden 387 kişiden anket yoluyla elde edilmiştir.Bulgular –Araştırmada altı hipotez test edilmiştir. Bu hipotezlerden dördü kabul edilmiş ikisi reddedilmiştir. Çoklu regresyon analizi sonuçlarına göre, iş ahlakıboyutlarından yöneticilerin ahlaki tutumlarının ve kurumun ahlaki tutumlarının örgütsel performans üzerinde pozitif ve anlamlı bir etkiye sahip olduğu belirlenmiştir. Buna karşın iş ahlakının çalışanların ahlaki tutumları boyutunun örgütsel performans üzerinde pozitif ama anlamlı olmayan etkiye sahip olduğu saptanmıştır.Tartışma –Örgütsel performansı en çok etkileyen iş ahlakı boyutunun kurumsal ahlaki sorumluluklar olduğu tespit edilmiştir. Çalışanlar arasında ayrımcılık yapılmaması ve çalışanların ve hastaların hakları konusunda yeterli hassasiyetin gösterilmesi örgütsel performansın göstergelerinden olan karlılığı, büyümeyi ve pazar payını olumlu yönde artıracağı söylenebilir.
Mediator Effect of Factors Affecting Credit Card Preference on The Effect of Consumers Personality Traits on Monthly Credit Card Usage Frequency
Authors: Gül Zekeriya , İşcan Orhan
Published: March 2022

Purpose – The point of the study is to examine the relationship between the personal characteristics of bank retail customers and the factors that may affect their credit card alternatives via the frequency of usage of such credit cards.
Design/methodology/approach – This study falls within the scope of correlational research model in this respect. The correlational research approach provides for the clarification of the relationship between variables as well as the prediction of the findings. This study's sampling is based on 610 bank retail customers who had access to credit lines defined using easily available sampling methodologies. The research findings are produced using the following criteria: (1) personality inventory as the primary factor, (2) frequency of credit card usage each month, and (3) factors that influence credit card preference. The total score for each criterion is established by the criteria applicable to subsequent factor analysis that were developed in line with the data that fell within the scope of this study.
Findings – As a result, the total scores were computed first. The skewness and kurtosis coefficients were calculated to determine whether or not such derived scores were distributed smoothly. The structural equation model was used to establish how the variables were clarified through the criteria used in credit card preference and customer behaviour based on the frequency of credit card use. According to the findings, when the factors impacting credit card preference that are based on the personal characteristics of retail customers are applied, the structural equation model used to establish for the instances that may have an influence on the frequency of credit card usage is substantiated.
Discussion – In principle, when the studies are analyzed, the relevance of a complex but holistic research setting that incorporates not only an overall scanning of the customers' psychologies but also future scenarios comes to the forefront in conformity with the results of this study.
On the Necessity and Feasibility of the Constitutional Judicialization
Authors: Liu Junchao
Published: March 2022

The proposal of "constitutional judicialization" is the product of the continuous development of constitutional theory and the needs of practice. Constitutional judicialization in a broad sense includes unconstitutional review and constitutional judicial judgment. The essence of constitutional judicialization in China is the judicial relief of constitutional rights, which aims to protect the basic rights of citizens. The judicialization of China's constitution must be carried out under the existing political and judicial system, so as to safeguard the people's democratic dictatorship and the people's Congress system. Specifically, we can effectively realize the judicialization of the Constitution in the form of indirect application of the constitution through constitutional interpretation, which can not only safeguard the authority of the National People's Congress and its Standing Committee, but also effectively protect the basic rights of citizens.
A Generalization of the Sum of Divisors Function
Authors: Cox Darrell , Ghosh Sourangshu , Sultanow Eldar
Published: March 2022

A generalization of the sum of divisors function involves a recursive definition. This leads to variants of superabundant numbers, colossally abundant numbers, and Gronwall's theorem (relevant to the Riemann hypothesis).
A Systematic Review of Low-Cost Real-time Air Quality Sensors, Systems, and Evaluation Methods
Authors: Tariq Hasan , Touati Farid , Crescini Damiano , Mnaouer Adel Ben
Published: March 2022

Air quality and environmental fairness have always been an area of prime interest across the globe. The significance low-cost air quality sensing and practices spikes during the time of pan-demic and epidemics when the air becomes a threat to living beings especially human beings. The gradual innovation and enrichment in low-cost air quality sensing sensors, nodes or devices, and systems are exponentially increasing for the last three decades. This work reviews the major contributions in a) low-cost scalable air quality assessment; b) low-cost air quality sensors, sensing approaches and technologies; c) low-cost state-of-the-art gas sensors fabrication methods (MEMS and CMOS); d) low-cost gas sensors measurement configurations and assemblies; e) low-cost air quality sensors calibration and testing systems; f) low-cost air quality measurement evaluation methods and key performance indicators; and g) machine learning-based evaluation for air quality sensors and measurements. A systematic review of past work with a goal to assist end-users, public health facilities, state agencies, researchers, scientists and air quality protection agencies has been rendered in this work. Starting from sensors electrodes to IoT based mobile smart nodes; all have been introduced in this article.
Global Longitudinal Strain and Global Circumferential Strain on Echo Heart Failure Score as 60-days Readmission Predictor in Congestive Heart Failure Patients with Left Ventricle Systolic Dysfunction in Makassar City
Authors: Muzakkir Akhtar F. , Amir Muzakkir , Kabo Peter , Saleh Khalid , Bahar Burhanuddin , Ghaznawie Aussie Fitriani , Tandean Frizt A. , Mappangara Idar
Published: March 2022

Introduction: The readmission rate due to heart failure increases every year in South Sulawesi. A Frequently used method for assessing readmission is an echocardiographic examination by measuring ejection fraction. However, recent studies show that the speckle tracking parameters are more sensitive to predict readmission of heart failure patients. In this study, we assess the role of Global Longitudinal Strain (GLS) and Global Circumferential Strain (GCS) parameters on the Echo Heart Failure Score (EHFS) as a 60-days readmission predictor in heart failure patients. Methods: We included 175 patients admitted through the inpatient installation of Integrated Heart Center Dr. Wahidin Sudirohusodo General Hospital. In addition, we reviewed up to 60 days after outpatient prospectively by collecting data through medical records. The correlation between echocardiographic parameters and readmissions was analyzed using the Spearman Rank Correlation. To determine each echocardiographic parameter's cut-off point, sensitivity, and specificity, we use Receiver Operating Characteristic (ROC) curve. Results:GLS and GCS are very sensitive and specific parameters in predicting 60-days readmission with an area under the curve (AUC) value > 0.7. This study shows that adding GLS and GCS parameters to the EHFS increases the predicted value (AUC 0.850 vs. 0.820) and sensitivity to 79%. Conclusion: GLS and GCS parameters additional on EHFS can help predict 60-days readmission of heart failure patients with sensitivity and specificity of 79% and 83%, respectively. The present study shows that with higher GLS and GCS scores on the EHFS, the risk of readmission in heart failure patients will increase.
Performance Analysis of SSK Modulation using multipath with multihop DF relay over Nakagami-m fading channel
Authors: RAMESH JUTTU , Sudha V
Published: March 2022

The data transfer between devices should be prominent in the future generations for Internet of Things (IoT) applications. IoT systems need a sophisticated communication setup with less hardware and complexity. Space Shift Keying (SSK) modulation is the perfect scheme to fulfill IoT system requirements by activating a single antenna. Moreover, Cooperative communication has more reliability in point-to-point communication by the relaying system. Thus, end-to-end Bit Error Rate (BER) in the multi-hop multi-branch relaying model under cooperative communication scenario using SSK modulation scheme for IoT systems is analyzed. The closed-form expression for BER is derived over Nakagami-m fading channels and the results are verified with Monte Carlo simulation.
Comprehensive bioinformatic analysis of the expression and prognostic significance of TSC22D domain family genes in acute myeloid leukemia
Authors: Xu XiaoQiang , Jin Xin , Wang JiaXi , Sun Rui , Zhang Meng , Xiong Xia , Xie DanNi , Zhao MingFeng
Published: March 2022

Background:TSC22D domain family genes, including TSC22D1-4, have been extensively reported to be involved in tumors. However, their expression profiles and prognostic significance in acute myeloid leukemia (AML) remain unknown.Methods:The present study investigated the expression profiles and prognostic significance of TSC22D domain family genes in AML through the use of multiple online databases, including the CCLE, EMBL-EBI, HPA, Oncomine,GEPIA2, UALCAN, BloodSpot, and GSCALite databases. The cBioPortal and GSCALite databases were used to explore the genetic alteration and copy number variation (CNV) of TSC22D3. TRRUST Version 2 was used to explore the gene ontology biological process, disease ontology, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways associated with TSC22D3. The AnimalTFDB3.0, STRING, and Harmonizome databases were used to investigate the protein–protein interaction (PPI) network of TSC22D3. Harmonizome was used for TSC22D gene regulatory kinase analysis. The TargetScanHuman 8.0, MiRDB, and ENCORI databases were used to execute the analysis of TSC22D3 regulatory miRNAs. Then, the GSCALite and GEPIA2021 databases were used to investigate the correlation between TSC22D3 expression and immune infiltration.Results:The expression of TSC22D3 was upregulated markedly in AML cells relative to normal hematopoietic stem cells. The expression of TSC22D3 was increased in AML group compared with normal control group. And overexpression of TSC22D3 was associated with poor OS in AML patients.Furthermore, gene ontology analysis revealed that TSC22D3 was involved in leukemia. Functional enrichment analysis indicated that TSC22D3 has many biological functions, including the regulation of many genes, kinases, miRNAs, signaling pathways, and immune infiltration.Conclusions:TSC22D3 expression was upregulated in AML, and overexpression was associated with poor OS in AML patients. Therefore, TSC22D3 may serve as a novel prognostic biomarker for AML.
Establishing the Taxa with Phylogenetic profile and in-silico-ayurvedic remedy of Microbiome of Bacterial Vaginosis
Authors: Geethashree S , Bagchi Preenon , Murthy Shylesh
Published: March 2022

Background: Bacterial vaginosis (BV) is a vaginal disease commonly caused by bacteria which most commonly causes abnormal vaginal discharge during women’s reproductive-age. BV is characterized by a shift within the vaginal flora from the dominant Lactobacillus to a polymicrobial flora and is further characterized by depletion of the resident lactic-acid-producing Lactobacillus spp. BV has been associated with serious health issues, including pelvic inflammatory disease and increased susceptibility to sexually transmitted diseases (STD) but itself is not a STD. Several genes and chromosomal regions have been found to be associated with BV in various linkage analyses, case-control studies, genome-wide association studies (GWAS), and admixture mapping studies.Methods: In this work, using BV microbiome we perform metagenome analysis which enables us to understand how the microbiome responds to the host by studying the functional analysis of genes expressed. The technology is used to determine the order of nucleotides or targeted regions of DNA or RNA. Krona pie chart is used for visualization of the taxonomy. Results: HUMAnN2 tool is used to determine the pathways and their abundance file of microbiome. Further, homology modelling of the BV gene receptors, Leucine Aminopeptidase 3 (LAP3) and Peptidase D (PEPD) was done and ligands from ayurvedic medicinal herbs were established. Conclusion: The taxonomy and functional information of BV microbiome are identified.
Preoperative prediction of sagittal imbalance in kyphosis secondary to ankylosing spondylitis after one-level three-column osteotomy
Authors: luo jianzhou , yang kai , yang zili , duan chunguang , chen jiayi , huang zhengji , luo zhenjuan , tao huiren , wu tailin
Published: March 2022

Background: This study aimed to determine preoperative predictions of sagittal imbalance in kyphosis secondary to ankylosing spondylitis (AS) after one-level three-column osteotomy. Methods: A total of 55 patients with AS who underwent one-level three-column osteotomy were enrolled. The patients were divided into two groups according to sagittal vertical axis (SVA) value at the final follow-up (group A: SVA>5 cm; group B: SVA≤5 cm). The radiographic measurements were measured, including global kyphosis, lumbar lordosis (LL), pelvic tilt (PT), pelvic incidence (PI), sacral slope, T1 pelvic angle (TPA), SVA, osteotomized vertebral angle and PI and LL mismatch (PI-LL). Results: Fifty-five AS patients were followed up for 30.6 ± 10.2 months averagely (range, 24–84 months). Preoperatively and postoperatively, group A had larger LL, PT, PI - LL, TPA, and SVA values than group B (P<0.05). And the preoperative LL, PT, PI - LL, TPA, and SVA values had significantly positive relationships with the follow-up SVA value (P<0.05). The preoperative TPA>40.9°, PI-LL>32.5°, and SVA>13.7 cm were the top three predictions with the best accuracy to predict sagittal imbalance. The construction of postoperative SVA<7.4 cm was the key factor for decreasing the chance of sagittal imbalance on follow-up. Conclusions: The preoperative TPA>40.9°, PI - LL>32.5°, and SVA>13.7 cm could predict sagittal imbalance for AS kyphosis after one-level three-column osteotomy, and additional osteotomies were recommended for this condition. The postoperative SVA<7.4 cm was an optimal alignment for preventing sagittal imbalance. Level of evidence: IV
Feasibility of a One-Day Driving Workshop for Combat Veterans During COVID-19
Authors: Stetten Nichole , Wandenkolk Isabelle , Jeghers Mary , Poojary Prerna , Winter Sandra , Classen Sherrilene
Published: March 2022

Background: Driving fatalities are a leading cause of death among combat Veterans. To improve Veterans' fitness-to-drive abilities, evidence-based interventions must be implemented. Objectives: Assess the feasibility of a one-day driving intervention for combat Veterans. Methods: The study objectives were examined using feasibility guidelines that examine recruiting capability; data collection procedures and outcome measures; acceptability and suitability of the intervention; available resources and participant responses. Results: COVID-19 and the study’s inability to convert to an online format (due to engagement with the driving simulator) hindered recruitment and study participation. Additional challenges for participants include fear of consequences from study participation, self-reflection of driving habits, workshop time burden, restrictive eligibility criteria and competing with another Veteran study. Conclusions : Despite meeting criteria for feasibility success, COVID-19 posed difficulties the study was unable to overcome. As recruitment efforts evolve to an online format, targeted social media marketing may be considered.
Comparison of Potassium-Competitive Acid Blockers and Proton Pump Inhibitors in Preventing Delayed Bleeding after Endoscopic Submucosal Dissection of Early Gastric Cancer: An Update Systematic Review and Meta-Analysis
Authors: Li Peng , Han Muzhou , Shi Haiyun , Cheng Rui , Liu Simao , Zhu Siying
Published: March 2022

Background: Proton pump inhibitors (PPIs) and potassium-competitive acid blocker (PCAB) are two different drugs that may be used after upper gastrointestinal endoscopic submucosal dissection (ESD). However, whether PCAB can reduce postoperative complications more than PPIs is a matter of controversy.Methods: We searched studies that reported the effectiveness of PCAB and PPIs in preventing delayed bleeding after gastric ESD by using PubMed, EMBASE, the Cochrane Library, Web of Science, etc. The Cochrane Risk of Bias Tool and Newcastle Ottawa Quality Assessment Scale were applied to evaluate the quality of the researches. All statistical analyses were carried out using Stata 15.1,including drawing the forest map, subgroup analysis, sensitivity analysis and detection of publication bias.Results: Seventeen studies with 51294 patients were included. There was a statistically difference in the overall delayed bleeding rate between the Vonoprazan group and the PPIs group. The overall mean relative risk (RR) for delayed bleeding following the administration of Vonoprazan was 0.72 (P<0.05) with a 95% confidence interval (CI) (0.67-0.77). However, there was no statistically difference in the incidence of blood transfusion events between the two groups[RR=0.76,95% CI (0.41-1.40)]. There was a statistical difference in the shrinkage ratio between the Vonoprazan group and the PPIs group. The weighted mean difference was 2.68(P<0.05) with a 95% CI (0.44-4.91). The sensitivity analysis showed all results were robust.Conclusions: Compared with PPIs, Vonoprazan showed a better efficacy in reducing the incidence of delayed bleeding and promoting the contraction of artificial ulcers. It might be an appropriate choice that postoperative management of gastric ESD in patients with stomach neoplasms.
Host-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired ECF transporter S component
Authors: Rodrigo M Kalindu , Saiganesh Aarti , Hayes Andrew , Anstey Jack , Iwasaki Jua , Pickering Janessa , Hillas Jessica , Winslow Scott , Woodman Tabitha , Lacey Jake , Linden Mark van der , Giffard Philip , Tong Steven , Stubbs Keith , Carapetis Jonathan , Bowen Asha , Davies Mark , Barnett Timothy
Published: March 2022

Described antimicrobial resistance mechanisms enable bacteria to avoid the direct effects of antibiotics and can be monitored by in vitro susceptibility testing and genetic methods. We have identified a new mechanism of sulfamethoxazole resistance that requires a host metabolite for activity. Using a combination of in vitro evolution and metabolic rescue experiments, we identified an energy-coupling factor (ECF) transporter S component gene (thfT) that enables Group A Streptococcus to acquire extracellular tetrahydrofolate and related compounds. ThfT likely modifies the substrate specificity of an ECF transporter to acquire the end products of folate biosynthesis. As ThfT-mediated resistance is undetectable by routine surveillance methods, our study highlights the need to understand antibiotic susceptibility during infection to reduce inappropriate antibiotic use and treatment failures.
Spatial distribution of soil organic matter and total nitrogen under relay strip intercropping system
Authors: Te Xiao , Hassan Muhammad Jawad , Cui Kuoshu , Xiao Jiahui , Aslam Muhammad Naveed , Saeed Amjad , Yang Wenyu , Ali Safdar
Published: March 2022

Assessing the spatial distribution of organic matter and total nitrogen in soil is essential for management and optimum utilization of fertilizers in order to obtain better crop yield with minimum fertilizers cost. Subsequently, this field experiment has studied the impact of different planting patterns arrangements of maize and soybean strip relay intercropping on spatial distribution of soil total nitrogen and organic matter contents. The planting was arranged in a manner that soil sampling could be done from continuous maize/soybean relay strip intercropping (MS1), maize/soybean relay strip intercropping in rotations (MS2), Traditional maize/soybean intercropping (MS3), sole maize (M), sole soybean (S), and fallow land (FL) from 2018 to 2020. The results showed significant variations for soil organic matter and total nitrogen under different planting patterns of maize and soybean in intercropping. The highest soil organic matter (29.19 g/kg) and total nitrogen (10.19 g/kg) were MS2. In contrast the minimum organic matter (1.69 g/kg) and total nitrogen (0.64 g/kg) were FL. Soil organic matter and total nitrogen in MS2 increased by 186.45% and 164.06%, respectively, compared with FL. Furthermore, under MS2, the spatial distribution of soil organic matter was higher in both maize and soybean crop rows as compared with other cropping patterns, whereas the soil total nitrogen was higher under soybean rows as compared with maize in all other treatment. However, the correlation analysis of the treatments showed variations for organic matter. It can be concluded that different planting patterns can have other effects on soil organic matter and total nitrogen distribution under intercropping. Moreover, it is recommended from this study that MS2 is a better planting pattern for strip intercropping, that can increase spatial distribution of soil organic matter and total nitrogen, consequently it can improving the soil fertility and C:N ratio.
Characterization of Danube Swabian population samples on a high-resolution genome-wide basis
Authors: Bánfai Zsolt , Kövesdi Erzsébet , Sümegi Katalin , Büki Gergely , Szabó András , Magyari Lili , Ádám Valerián , Pálos Ferenc , Miseta Attila , Kásler Miklós , Melegh Béla
Published: March 2022

Background
German-derived ethnicities are one of the largest ethnic groups in Hungary, dating back to the formation of the Kingdom of Hungary, which took place at the beginning of the 11th century. Germans came to Hungary in many waves. The most significant immigration wave took place following the collapse of the Ottoman Empire in East-Central Europe which closed the 150-year long Ottoman occupation. To date, there are no comprehensive genome-wide studies investigating the genetic makeup of the Danube Swabians. Here we analyzed 47 Danube Swabian samples collected from elderly Danube Swabian individuals living in the Dunaszekcső-Bár area, Danube side villages in Southwest Hungary. Based on self-declaration they did not admix with other ethnic groups for 3–6 succeeding generations. Using Illumina Infinium 720K Beadchip genotype data, we applied allele frequency-based and haplotype-based genome-wide marker data analyses to investigate the ancestry and genetic composition of the collected Danube Swabian samples.
Results
Haplotype-based analyses like identity by descent and homozygosity by descent analyses show that the investigated Danube Swabians remained isolated from other ethnic groups which was supported by the D-statistics results. According to our results, the investigated Danube Swabian individuals do not possess detectable recent admixture, and our results suggest that their main source of ancestry can be traced back to the region of Germany.
Conclusions
This is the first analysis of Danube Swabian population samples based on genome-wide autosomal data. Our results establish the basis for conducting further comprehensive research on Danube Swabians and on other German ethnicities of the Carpathian basin, which can help reconstruct their origin, and identify their major archaic genomic patterns.
The Role of ATP-binding Cassette Transporter Genes Expression in Treatment Failure Cutaneous Leishmaniasis
Authors: Boozhmehrani Mohammad Javad , Eslami Gilda , Khamesipour Ali , Jafari Abbas Ali , Vakili Mahmood , Hosseini Saeedeh Sadat , Askari Vahideh
Published: March 2022

Leishmaniasis is one of the common diseases transmitted by sand flies in tropical and subtropical regions of the world. Currently, antimonial derivatives are the first line of treatment. Some of the members of the ATP-binding cassette (ABC) family of Leishmania are shown to be associated with no response to treatment. In this study, we evaluated ABCI4 , ABCG2, ABCC7, ABCB4, and ABCC3 genes expression in Leishmania isolated from patients with non-healing cutaneous leishmaniasis and treatment response isolates. We selected 17 clinical isolates (8 treatment failure and 9 treatment response) obtained from patients of Health Center Laboratory of Varzaneh, Isfahan, Iran, from September 2020 to March 2021 with cutaneous leishmaniasis. The diagnosis was performed using microscopic observation. The samples were directly collected from the lesions. The expression profiling of genes was assessed using SYBR Green real-time PCR that was analyzed with delta-delta Ct. All treatment failure clinical isolates were L. major . Gene expression analysis in treatment failure isolates showed that the ABC transported genes had a different pattern in each isolate. Treatment failure has been reported for cutaneous leishmaniasis worldwide. Knowledge of the molecular mechanisms of treatment failure could solve this problem. ABC transporter genes are considered controversial over the mechanisms of treatment failure outcomes. In this study, we showed that ABC transporter genes could be considered one of the important mechanisms.
Characteristics of neutralization process of acid mine drainage with steel slag
Authors: Yang Lei , Tang Yuegang , Yang Mingyuan , Cao Duanning , Lu Cunfang , He Yuanyuan
Published: March 2022

Steel slag has been proven to be an effective environment remediation media for acid neutralization, and a potential aid to mitigate acid mine drainage (AMD) in passive treatment process. In application, the acid neutralization capacity (ANC) of the steel slag is often decreased after a period of use because of the precipitate formation. However, the characteristic of the formation process are unclear yet. In this work, we tested the ANC of the commonly used Basic Oxygen Furnace (BOF) steel slag by titration of simulated AMD (H2SO4, 0.1M) and real AMD from abandoned coal mine drainage in the southwestern of China. The result indicated that there was a linear relationship between pH value and titrated AMD amount, for both simulated AMD and real AMD. When the pH decreased to 7, the titrated AMD amount and ANC were about 40ml and 8mmol H+/g slag for simulated AMD. At the beginning of the titration process, dissolution and hydration reactions of the easily dissolved calcium-containing constitute played a dominant role, and then were the precipitation formation reactions. The turning point for the two reactions was occurred when 20 % of the total titrated amount was titrated. Meanwhile, the BOF slag surface became smooth, and the dissolution reactions were hindered when the slag surface was clogged by the new formed crystallized gypsum. Further titration experiments results by real AMD also confirmed the ANC variation of BOF samples during the neutralization process.
Burnout among Psychotherapists: A Cross-cultural Value Survey among 12 European Countries during the Coronavirus Disease Pandemic
Authors: Hoy Angelika Van , Rzeszutek Marcin , Pięta Małgorzata , Mestre Jose M. , Mora Álvaro Rodríguez , Midgley Nick , Omylinska-Thurston Joanna , Dopierala Anna , Falkenström Fredrik , Ferlin Jennie , Gergov Vera , Lazić Milica , Ulberg Randi , Røssberg Jan Ivar , Hancheva Camellia , Stoyanova Stanislava , Schmidt Stefanie , Podina Ioana , Ferreira Nuno , Kagialis Anthony , Löffler-Stastka Henriette , Gruszczyńska Ewa
Published: March 2022

Objective
The aim of this study was to examine cross-cultural differences, as operationalized by Schwartz's refined theory of basic values, in burnout levels among psychotherapists from 12 European countries during the coronavirus disease (COVID-19) pandemic. We focused on the multilevel approach to investigate if individual- and country-aggregated level values could explain differences in burnout intensity after controlling for sociodemographic and work-related characteristics and COVID-19-related distress among participants.
Methods
In this study, 2915 psychotherapists from 12 countries (Austria, Bulgaria, Cyprus, Finland, Great Britain, Serbia, Spain, Norway, Poland, Romania, Sweden, and Switzerland) participated in this study. The participants completed the Maslach Burnout Inventory-Human Service Survey, the revised version of the Portrait Values Questionnaire, and a survey questionnaire on sociodemographic and work-related factors.
Results
Multilevel analysis revealed that burnout at the individual level was negatively related to self-transcendence and openness-to-change values but positively related to self-enhancement and conservation values. However, no significant effects on any values were observed at the country level. Moreover, male sex, younger age, being single, and reporting higher COVID-19-related distress were identified as significant burnout correlates.
Conclusions
Burnout among psychotherapists may be a transcultural phenomenon, where individual differences among psychotherapists are likely to be more important than differences between the countries of their practice. This finding enriches the discussion on training in psychotherapy in an international context and draws attention to the neglected issue of mental health among psychotherapists in the context of their professional functioning.
A comparison of magnetic resonance imaging and cone beam computerized tomography in the evaluation of temporomandibular joint changes in rheumatoid arthritis patients
Authors: Jalal Ranj Adil , Ahmed Khadija Muhamad , Saeed Shahla Muhamad
Published: March 2022

Objectives: This study aimed to determine the features of temporomandibular joint involvement in rheumatoid arthritis patients and to examine the association of radiographic changes with RA duration by comparing the diagnostic efficacy of cone-beam computerized tomography to magnetic resonance imaging in identifying changes of TMJs.Methods: This case-control study was performed on 40 RA patients with 10 healthy adults (control cases). Clinical examination with CBCT and MRI as well as laboratory tests were done for participants. Independent and paired t-tests and correlation coefficient test were used for data analysis by SPSS program Results: The frequency of TMJ involvement using CBCT and MRI techniques were 82.5% and 87.5% in RA patients and were 50% and 30% in control cases. The most frequently observed clinical symptom was facial pain (25%), and the slightest symptom was clicking (2.5%) during mouth opening. The commonest change in CBCT of RA patients was condylar head erosion (67.5%), and the less common change was articular eminence erosion (7.5%). The commonest changes in MRI of RA patients were an osseous change of condylar head (80%), and the minor change was effusion (10%), while in controls were an osseous change of condylar head (30%) and condylar head flattening (10%). There was a positive correlation between ESR, RF, and Anti-CCP and osseous TMJ changes, while CRP shows a negative correlation. Conclusions: Osseous changes occur in TMJs of RA patients with no/mild symptoms, MRI can be used as efficient imaging modality for detecting changes in TMJ, and elevated ESR, RF and Anti-CCP may indicate the presence of osseous changes in RA patients.