bluuebunny/crossref_metadata_2025 huggingface dataset:
The Sonic Hedgehog Signaling and Its Components in Recurrent Chordoma of the Spine
Authors: Akhavan-Sigari Reza , Angelika Harcej Amanda , Herlan Stephan , Trakolis Leonidas
Published: December 2021

Objective Chordomas are uncommon primary malignant tumours that have a high rate of recurrence. They are thought to form along the spine from remains of the embryonic notochord. Treatment for recurrent tumours is complicated and contentious.They are unresponsive
to conventional chemotherapy and radiotherapy. Chordomomas simply lack a viable chemotherapeutic standard. Throughout the fetus's development, the Sonic Hedgehog (SHH) pathways connecting a variety of processes involved in tissue and organ expansion and differentiation. To investigate the
role of signalling the hedgehog in recurrent spinal chordomas, immunohistochemistry was used to identify SHH and GLI1 levels. In situ hybridization was also used to differentiate PTCH1 and GLI1 expressions. Methods From 1997 to 2020, we looked at 23 paraffin-embedded
recurrent spinal chordoma samples from 23 patients (9 men, 14 women; median age: 63 years). All the patients were treated at the University Medical Center Goettingen in Germany and Azad University of Medical Sciences in Tehran, Iran. This study only included patients who had been diagnosed
with conventional chordoma. Results SHH expression (+) and GLI1 expression were discovered in all 23 cases (+) immunohistochemically. GLI1 and SHH levels were markedly increased by recurrent spinal chordoma scores. In the recurrent spinal chordoma, in situ hybridization
demonstrated positive responses for PTCH1 and GLI1. Conclusion The Shh sample that represents is believed to play a role in spinal chordoma recurrence.The increased amounts of SHH and GLI1 activity in all chordoma samples, according to the study, indicate
an autocrine ligand-dependent activation of the conventional HH signalling cacade. It's hard to rule out a non-canonical or paracrine pathway. Hedgehoginhibitors, such as SHH- and GLl-inhibitors, are believed to be associated in our findings, could be a promising approach for treating recurrent
spinal chordomas.
Combination Therapy with EGFR Specific CAR_NK_92 Cells and Cabozantinib against Human Renal Cell Carcinoma
Authors: Huang Youqing , Zhong Yong , Qin Chunhui , Wang Hao
Published: December 2021

Adaptive therapy using immune effector cells engineered by means of chimeric antigen receptors (CAR) has risen as a hopeful cancer management option. Despite their unprecedented success in haematological malignancies, CAR-modified T cells have shown limited efficacy in solid tumours,
as the tumor’s immune-suppressive microenvironment inhibits CAR-modified immune effector cells’ functionality by different pathways, counting checkpoint receptor ligands expression like PD-L1 & recruitment tregs like suppressive immune cells. Receptor of epidermal growth factor
(EGFR) could be the target of a ll-generation Chimeric antigen receptor T cellshat was transduced to NK-92 cell. In our research, we examined the antitumor efficacy of EGFR specific NK-92 (CAR-NK-92) cells using a xenograft mice model & in conjunction with tyrosine kinase inhibitor cabozantinib.
We discovered that EGFR positive renal carcinoma cells (RCC) 786-0 and ACHN may specifically detect and activate CAR_NK_92 cells. They also displayed particular cytotoxicity against RCC in in vitro & in vivo models. Furthermore, we discovered that cabozantinib improves RCC-specific cytotoxicity
by enhancing the expression of EGFR while reducing PD-L1 expression in RCC. Our research shows that CAR_NK_92 cells possess anti cancer therapeutic potential for EGFR-positive tumour cells, and that cabozantinib can boost CAR_NK_92 cell cytotoxicity when treated together.
Research on Emotional Expression of Daily-use Ceramic Product Design Based on Meta-model
Authors: Zhu Junxi , Wei Wenqing
Published: December 2021

Objectives: Modern people’s pursuit and consumption of ceramic products are different from those in the past. Therefore, designing new daily ceramic products full of enthusiasm, touching and spiritual enjoyment is our constant pursuit of innovative goals. The design of daily-use
ceramics has developed from satisfying the needs of life at first to pursuing the individuality and emotion of products at later stages, showing different cultural connotations and pursuits in each stage of development. Methods: Information objects under meta-model are obtained by extracting
the characteristics of project management information and product design information, reflecting the relationship between information entities, while knowledge objects are obtained by associating related information objects. Results: Emotional information products have more understanding of
human psychology in the design process, which runs through the whole process of product interaction design. Conclusion: Through theoretical analysis of emotional design and analysis of a series of classic design cases of daily ceramic products, emotional expression forms of daily ceramic product
design are summarized, and emotional design products that can bring people better use experience are designed.
Application Analysis of Physical Fitness Test Performance Management Based on Improved Ant Colony Algorithm
Authors: Chen Dong
Published: December 2021

Objectives: With the continuous development of quality education in China, higher education pays more and more attention to the development of physical education. However, in the process of China’s development, there is a lack of corresponding evaluation system for physical
fitness test results. Methods: Therefore, this paper proposes the analysis and research application of fitness test performance management based on ant colony algorithm. Firstly, it expounds the development status of physical education performance management. Results: Then, aiming at the corresponding
shortcomings, this paper puts forward the application analysis of the fitness test performance management platform based on the mixed mode of cloud theory, and carries out a series of comprehensive tests on the system. Conclusion: According to the performance test of all aspects of the database,
the test results show that the system is feasible.
Oscillation analysis of numerical solution of Nonlinear Operator Equation
Authors: Zhou Yang , Li Cuimei
Published: December 2021

There is a problem of low accuracy in the analysis of the vibration of the numerical solution of the nonlinear operator equation. In this work, the vibration analysis equation is constructed by the step-by-step search method, and the vibration quadrant of the equation is divided
by the dichotomy method. The vibration spectrum is determined by the iteration method, and the vibration analysis model of the numerical solution of the nonlinear operator equation is constructed. The vibration analysis of the numerical solution of the nonlinear operator equation is completed
based on the solution of the model and the numerical calculation and display of the step-by-step Fourier. The experimental results show that the proposed method has higher accuracy than the traditional vibration analysis method, which meets the requirements of the vibration analysis of the
numerical solution of nonlinear operator equation.
Effects of Smoking Behavior and Cognition of Tobacco Control on Digital Entertainment and Mental Health of School-Age Children during Holidays
Authors: Yanghuan Long , Qiang Wang , Zhenwei Yu , Yu Guo , Xiangyu Liu , Mengjie Shi
Published: December 2021

Objectives: We studied the consequences of parental domestic smoking behavior on children’s digital entertainment and mental health during COVID-19, and put forward the initiative of family tobacco control toprotect children’s physical and mental health. Methods: From
February 20 to February 23, 2021, using Sojump survey method, 800 smoking parents who live with children aged 6∼12 answered the questionnaire online about basic information, children’s digital entertainment status, strengths and difficulties (SDQ). Results: 60.8% of the children
exposed to secondhand smoke spend more than 1 h on digital entertainment every day; abnormal detection rates of emotional symptoms, conduct problems, hyperactivity and inattention, peer interaction, pro-social behavior, and difficulty total scores are 29.2%, 38.2%, 6.5%, 80.3%, 22.0%, 40.0%,
respectively. Single factor analysis suggests that there are statistical differences in the degree of impact of household monthly income and children’s life under smoking parents on digital entertainment duration (χ= 14.76, 10.88; P <0.01). Binary logistic regression analysis
reveals that more than 1 hour of digital entertainment per day is an important factor that triggers school-age children’s emotional symptoms, peer interactions, difficulties and high risks (OR=1.68, 1.89, 1.65; P<0.05). Conclusions: The greater the impact of parents’ smoking
on children’s life, the higher the proportion of children’s excessive digital entertainment. The excessive digital entertainment will bring many mental health hazards to children. In particular, the children long endurance to secondhand smoke are more possibly to have adverse reactions
like emotional symptoms, misconduct issues, hyperactivity and inattention.
Evolution of the inscriptions on the Bronze Mirror of Han Dynasty in the Furnace Smoke
Authors: Zhongfeng Xu
Published: December 2021

The Chinese characters evolution fromseal script to clerical script in Han Dynasty underwent one a new process of development and stability from top-level design to folk application, where the most important relic, inscriptions of bronze mirror, together with the bamboo slips and
stele inscriptions, constituted the basic calligraphy aestheticsat that time, forming historical legends in the smoke of casting. Among the mirrors of Han Dynasty, there are a lot of surviving inscription mirrors, the chirography on which has extremely rich subjective design, showing important
aesthetic characteristics. Most of the previous writings have tended to study explanation and entry, and there are few studies based on the chirography. The classification and analysis of the considerable and complex inscriptions of bronze mirror based on archaeological typology indicate that
at different stages and in different regions, the sources of popular materials are similar, with typical styles gradually appearing, different creative effects, as well as fresh and interesting cases. Comparing the inscription chirography with bamboo and wood slips and calligraphy on rubbings,
it is possible to see the combination of “mirror caster” and “ Daobili (petty official drawing up indictments)”, new calligraphic patterns appear in the smoke of the fire. The calligraphy is applied to bronze mirrors, and is cut and transformed by the craftsmen to be
suitable for deformation, so that the character shape is integrated with bronze and stone tablet casting, presenting a unique decorative taste and design meaning, carrying the open and inclusive spirit of Han Dynasty.
Optimization Model of Local Policy on Rural Tourism Income Based on Particle Swarm Optimization Zhonghui Kang
Authors: Kang Zhonghui
Published: December 2021

Under the background of the implementation of Rural Revitalization Strategy, rural tourism has become another important way to drive rural development and realize rural revitalization after the mechanized operation mode. Relying on the characteristics of rural resources, rural tourism
gives full play to its role. Aiming at the problems of agriculture, rural areas and farmers, it optimizes the resource allocation structure in rural areas, coordinates the industrial development, and constructs the characteristic rural tourism mode to meet the spiritual needs of contemporary
people. With the development of new rural tourism mode relying on agricultural resources, such as research base, agricultural industrial park, characteristic towns and so on, more and more people love rural tourism. The development of rural tourism injects new vitality into rural areas, promotes
the growth of rural regional economy, effectively increases farmers’ employment, promotes industrial integration, and is conducive to solving the “three rural” problems, reducing poverty, and promoting the construction of a well-off society.
Research on the Regeneration Status and Development Mode of the Landscape of the Third Tier Construction Industry Sites in China under the Background of Urban Renewal
Authors: Liu Yanlong , Liang Xuan , Yu Rong , Li Jie
Published: December 2021

Industrial sites are brownfields left in the process of urban development, which were originally considered as the burden of the city. However, in today’s lack of land resources, industrial sites have become valuable assets of the city. Further excavation and effective use
of them is one of the important ways to alleviate the tension of urban land use. The strategy of ecological reconstruction and sustainable design in the landscape of industrial sites is mainly reflected in the minimal intervention in the natural ecology of the site, the use of renewable materials
and resources, the retention of native plants, human history and site memory. It makes the ecology of urban industrial site landscape more balanced, enhances the uniqueness and experience of urban industrial site landscape, meets the spiritual and physiological needs of people in the city,
and realizes the sharing of industrial site landscape to the public’s natural ecology, land, industrial spirit, history and humanity.
Clinical Significance and Prognostic Factors of Simultaneous Heart Valve Surgery and Coronary Artery Bypass Grafting in Treating Patients with Valvular Heart Disease Complicated by Coronary Heart Disease
Authors: Qiu Shi , Sun Jinhui
Published: December 2021

This study was designed to evaluate the clinical significance of simultaneous heart valve surgery and coronary artery bypass grafting for patients with valvular heart disease complicated by coronary heart disease and its influence on their prognosis. A total of 121 patients with
valvular heart disease complicated by coronary heart disease who were surgically treated in our hospital from January 2013 to March 2017 were selected. The observation group (OG) (64 patients) underwent simultaneous valvular heart surgery and coronary artery bypass grafting. The control group
(CG) (57 patients) underwent non-synchronous heart valve surgery and coronary artery bypass grafting. The operation, hospitalization, occurrence of adverse events and changes of cardiac function indexes of patients from the two groups were compared, and the factors affecting their prognosis
were confirmed in multivariate analysis. The ventilator application time, postoperative ICU monitoring time, postoperative general ward time and total incidence of adverse events in the OG were lower than those in the CG (P<0.05). After treatment, the cardiothoracic ratio, left ventricular
end-diastolic volume and BNP content in the two groups were markedly higher than before treatment, and the increase in the OG was more obvious (P<0.05); the left ventricular ejection fraction in both groups was markedly lower than that before treatment (P<0.05), and the decrease in the
OG was more obvious (P<0.05). Multivariate analysis showed that hypertension, treatment methods, course of disease and age were independent risk factors affecting the prognosis of patients with valvular heart disease complicated by coronary heart disease. Simultaneous heart valve surgery
and coronary artery bypass grafting can reduce the occurrence of adverse events and improve cardiac function indexes, which is worthy of clinical application. Hypertension, treatment methods, course of disease and age are independent risk factors affecting the prognosis of those patients.
LncRNA XIST Relieves Hypoxia-Induced Damage in H9C2 Cells by Downregulating miR-429
Authors: Yu Na , Han Xue , Wang Xueqin , Yu Wanling , Yan Liqiu
Published: December 2021

This paper aimed to investigate LncRNA XIST relieving hypoxia-induced damage in H9C2 cells by downregulating miR-429. Rat H9C2 cell lines were selected and divided into a normal control group, a hypoxia group, a XIST expression group, a XIST blank expression group, a miR-429 interference
group and a blank interference group. qPCR was adopted for detecting LncRNA XIST and miR-429 expression. Western blot (WB) was adopted for detecting the expression of AMPK, PDH, FAT, MCPT-1, Caspase-3, Bax and Bcl-2, ATP content, and levels of SOD, MDA and LDH. Dual luciferase reporter gene
assay (DLRGA) and RNA pull-down were adopted for verifying the correlation of LncRNA XIST with miR-429. Hypoxia-induced H9C2 cells had low LncRNA XIST expression and high miR-429 expression. LncRNA XIST upregulation or miR-429 downregulation could inhibit AMPK, PDH, Caspase-3 and Bax, upregulate
FAT, MCPT-1 and Bcl-2, and increase ATP content and SOD activity, as well as reduce MDA content and LDH activity. miR-429 was the target gene of LncRNA XIST. LncRNA XIST can relieve hypoxia-induced damage in H9C2 cells via binding to and downregulating miR-429
College English Teaching under the Internet Plus Background
Authors: Beibei Gao
Published: December 2021

The development and promotion of Internet emerging technology has brought incomparable practical significance and new development ecology for College English education industry. As a significant part of College English teaching. University English audio-visual-oral course undertakes
the significant task of strengthening English listening and speaking ability, broadening international vision and improving intercultural communication ability. Due to the “Internet plus”, the education pattern of College English reading, writing, oral English and listening can
adopt a blended teaching mode to boost the on-and offline education of audio-visual and intelligent education. The paper first analyzes the common problems in the traditional college and university English language education mode, and puts forward the concept of blended teaching mode, and
concludes the path and measures of the reform of College English language teaching mode under the Internet Plus background.
Nursing Experience of Octreotide in Treating Hypoglycemia in Acute Pancreatitis
Authors: He Li , Zhang Xueli , Li Fengchun , Liu Weiping , Wu Chenxia
Published: December 2021

This article studies the therapeutic effect and nursing experience of octreotide in treating hypoglycemia in acute pancreatitis. Method: Sixty patients with acute pancreatitis treated in our hospital from January 2019 to February 2020 were selected as the study subjects, and the
patients who met the criteria were randomly divided into intervention group (n=30) and control group (n=30).Both groups of patients were treated with octreotide, while the intervention group was given personalized whole-course intervention on the basis of it, to compare the treatment effect
of the two groups and the occurrence of hypoglycemia. Results: The total effective rate was 73.33% in the control group and 96.67% in the intervention group. There was a significant difference in data between the intervention group and the control group (P < 0.05). The incidence of hypoglycemia
was 26.67% in the control group and 3.33% in the intervention group. The difference between the control group and the intervention group was statistically significant (P < 0.05). The incidence of adverse reactions was 36.67% in the control group and 6.67% in the intervention group. The
difference between the control group and the intervention group was statistically significant (P < 0.05). The nursing satisfaction of the patients in the control group was 79.00%, and that of the intervention group was 96.67%. The difference between the intervention group and the control
group was statistically significant (P < 0.05). Conclusion: Octreotide has a good effect in the treatment of patients with acute pancreatitis. If personalized whole-course intervention can be given to patients with acute pancreatitis who receive 24-hour octreotide pump drip, the treatment
effect, nursing satisfaction, adverse reactions and hypoglycemia can be further improved, and the patient’s condition can be effectively maintained stable and the patient can recover as soon as possible.
Observation of Nursing Care of Patients with Acute Severe Pulmonary Embolism after General Surgery under Microscope
Authors: Liang Wenbin , Shen Jing , Zhang Yuanling , Li Hongbing , Yu Bangxing
Published: December 2021

Acute pulmonary embolism (APE) is one of the common acute and critical illnesses in clinical medicine, and it is another high cause of death after heart disease, cancer and cardiovascular disease. Despite the unremitting research and exploration of many relevant experts in recent
years, major progress has been made in diagnosis and treatment, but the clinical manifestations of acute pulmonary embolism are not specific, and there is a lack of effective and definite methods for diagnosis. The mortality rate of patients with acute pulmonary embolism remains high. Furthermore,
the combination of multiple postoperative diseases caused by general surgery can also increase the mortality of patients. Based on this, this article uses microscope technology to study and analyze the pretreatment methods and nursing methods of patients with acute severe pulmonary embolism
after general surgery to improve the condition of patients with acute pulmonary embolism and increase their recovery rate, hoping to be the domestic acute pulmonary embolism The treatment provides reference and reference. This article first summarizes the relevant theories of surgery and acute
pulmonary embolism, and then uses experimental methods, data analysis methods, survey methods and comparison methods, and SPSS 22.0 statistical analysis software technology to observe the efficacy of patients after thrombolytic therapy through a microscope. It is concluded that in the sample
data of 50 cases, the significant rate accounts for 58%, the effective rate accounts for 36%, and the inefficiency accounts for 6%, confirming the positive impact of early thrombolytic therapy on patients with acute pulmonary embolism. Finally, through the microscope observation and comparison
of the patient’s physical signs before and after nursing, it is concluded that timely and effective nursing after surgery has a great effect on improving the treatment rate of patients.
Application Effect of Comprehensive Nursing Intervention Model in Nursing of Children with Epilepsy
Authors: Wang Jin , Chen Wei , Lai Yanfang
Published: December 2021

At present, the epilepsy disease of children in the growing groups of children and adolescents in my country is a very common mental disease, and it is very important to strengthen the early comprehensive treatment care and intervention therapy for children with epilepsy. The purpose
of this study is to deeply explore the specific application effect of this comprehensive clinical nursing intervention model in the clinical nursing treatment of early childhood epilepsy patients. In this research, 80 cases of children with new-type pediatric epilepsy who received rehabilitation
treatment in our hospital from August 2018 to December 2019 were selected as the observation objects of the clinical study.The children in the control group received short-term routine rehabilitation care, while the observation group adopted short-term comprehensive rehabilitation care and
interventional treatment in parallel with long-term clinical rehabilitation care. The results of the research analysis show that the observation group’s hospitalization satisfaction of children with acute epilepsy is 96.73%, which is significantly higher than that of the general control
group, 85.32%. The compliance rate of hospitalized children with acute epilepsy in the observation group was 95.22%, which was significantly higher than that of the general control group, 83.48%. The difference was obviously statistically significant (p<0.05). It can be seen from this that
the treatment of children with epilepsy early adopting comprehensive nursing intervention mode can effectively improve the effect of epilepsy treatment.
Long Term and Low Dose Mifepristone in The Treatment of Uterine Leiomyoma
Authors: Liu Panpan , Dou Meifang , Yi Li’an , Li Kemei , Yan Fenghua
Published: December 2021

To explore the long-term effect of low-dose mifepristone in the treatment of uterine leiomyoma. Methods: 90 cases of hysteromyoma treated in our hospital from December 2018 to May 2019 were randomly divided into control group and observation group, 45 cases in each group. The control
group was treated with conventional dose (25mg / D) of mifepristone, and the observation group with low dose (12.5mg / D) of mifepristone. The uterine volume, uterine fibroid volume, hormone level, therapeutic effect and adverse reactions were compared between the two groups. Results: After
treatment, the volume of uterus and hysteromyoma in the two groups decreased significantly, but there was no significant difference between the observation group and the control group (P > 0.05); the level of E2, P, FSH in the two groups decreased, but there was no significant difference
between the observation group and the control group (P > 0.05); the treatment effect of the observation group and the control group was no significant difference (P > 0.05); the adverse reactions of nausea, anorexia, hot flashes and fatigue in the observation group The birth rate was
significantly lower than that of the control group (P < 0.05). Conclusion: Low dose mifepristone can also effectively reduce the level of estrogen and progesterone in patients with uterine leiomyoma, reduce the volume of leiomyoma, reduce the incidence of adverse reactions, with high safety,
which is worthy of clinical application.
TEMPLATE-SHAPE DEPENDENCE ASSEMBLY OF JANUS NANOPARTICLES AT WATER-OIL INTERFACE
Authors: Xatyeng Kongxiong , Vu Minh Tu , Pham Van Dien , Tran Manh Cuong , Do Hoang Tung , Pham Van Hai
Published: December 2021

In this work, we investigated the crystal formation of anisotropic nanoparticles, namely Janus particles, at the water-oil interface using the dissipative particle dynamics simulation method. By considering three different interface templates, including planar, droplet, and rod, we observe an increase of the disorder-order transition packing fraction with increasing the curvature radius of the templates. Furthermore, the nanoparticles in the planar template assemble into a hexagonal lattice, while for the two remaining templates they aggregate into colloidsome-like structures.
COMPUTER SIMULATION OF LOCAL STRUCTURE AND DIFFUSION MECHANISM THROUGH VORONOI POLYHEDRONS IN SODIUM SILICATE GLASS
Authors: Giap Thi Thuy Trang , Nguyen Thi Thao
Published: December 2021

The Na2O.SiO2 glass has been studied at different temperatures from 300 K to 1173 K by using molecular dynamics simulations. The Voronoi Si and O polyhedrons are analyzed to evaluate the displacement of sodium between these polyhedrons. The results show that more than 90% of the total number of Na is located in NBF polyhedrons that contain non-bridging (NBO) and free oxygen (FO) polyhedrons. The site energy for Na atoms located in NBF is smaller than one in BO polyhedron. The diffusion process of Na atoms is occurred in two ways: the first one is the alone jumping of Na in BO polyhedrons and the second one is the mixed alone jumping of Na and the cooperative movement of Na in NBF polyhedrons. The calculation of the average time between two consecutive jumps and the visiting time for Na atoms leads to the correlation effect for the diffusion of Na atoms. This effect depends on the temperature of the samples.
STUDY ON THE VARIATIONS OF THE FATTY ACIDS AND AMINO ACIDS OF GREEN PEEL AVOCADO IN SON LA PROVINCE AT DIFFERENT HARVESTING MATURITY
Authors: Nguyen Van Loi
Published: December 2021

Green peel avocado is a fruit with high nutritional value, rich in lipids, proteins, sugars, vitamins, and minerals. The aim of this study was to determine the change in fatty acid and amino acid content of green peel avocados harvested at 200, 210 and 220 days in order to select the appropriate harvest time, serving for efficient preservation and processing. The results of the study showed that 9 fatty acids were identified at the time of harvesting at 200 days, 10 fatty acids at the time of harvesting at 210, and 220 days of green peel avocado. Compared with two harvest times as 210, and 220 days since fruiting, the fatty acid content of green peel avocado did not differ so much. By using the HPLC method, 13 amino acids, 14 amino acids, and 15 amino acids were identified at 200, 210, and 220 days after fruiting, respectively. Glycine, alanine, lysine, and phenylalanine were intended to increase in the developmental stages of green peel avocado, whereas the other amino acids did not change much. Therefore, based on the change in fatty acid and amino acid content, green peel avocado farmers in Son La province should choose the time of harvest from 210 to 220 days from fruiting to be suitable for preservation and processing. If harvesting green peels avocados at more than 220 days after fruiting, it will make the dried fruit and spongy, and affect flowering, fruit set, and yield in the next fruit crop.
ADDITIONAL DATA ON SPECIES COMPOSITION OF FISH IN TIEN HAI WETLAND NATURE RESERVE, THAI BINH PROVINCE
Authors: Ta Thi Thuy , Pham Thi Thao , Tran Duc Hau
Published: December 2021

Mangrove forests are important for many fish species, but this information is still poorly understood in Vietnam. Tien Hai Wetland Nature Reserve is located in the core areas of the Red River Delta Biosphere Reserve, where mangrove forests are presented. To provide fundamental data for a better understanding of the role of mangroves for fishes, three surveys in March, July, and August 2019 at 5 stations within Tien Hai Wetland Nature Reserve were conducted. A total of 817 individuals were collected and 65 species belonging to 54 genera, 28 families of 11 orders were identified. Of the 11 orders, Perciformes was the most diverse in a number of families, and Gobiiformes was dominant in the number of species. Of the 65 species, three were listed in Vietnam Red Data Book (2007), i.e., Bostrychus sinensis as CR level, Clupanodon thrissa as EN level, Konosirus punctatus as VU level, and an invasive alien species (Oreochromis mossambicus). The present study added 15 species to the study site and 10 fish to the lowland of the Red River in comparison with previous works. In the additional list, there were some typical species, which are associated with mangrove forests, such as Escualosa thoracata, Muraenichthuys gymnopterus, and 17 species of gobies. The ichthyofauna in Tien Hai Wetland Nature Reserve was different from Phu Long mangrove forests (in Hai Phong), and significantly different from Van Uc estuary (in Hai Phong) and Bung Binh Thien wetland (in An Giang). These findings will be valuable for fish conservation and fisheries resources development in the study area.
GENOME-WIDE IDENTIFICATION AND COMPUTATIONAL CHARACTERIZATION OF THE NUCLEAR FACTOR-YC SUB-UNITS IN GRAIN AMARANTH (Amaranthus hypochondriacus)
Authors: Tran Thi Thanh Huyen , La Viet Hong , Le Thi Ngoc Quynh , Pham Chau Thuy , Ha Thi Quyen , Chu Duc Ha
Published: December 2021

Nuclear factor-Y (NF-Y) has been known as one of the plant-specific transcription factors that play key roles in numerous biological processes during the growth and development of plant species. In this study, a comprehensive analysis of NF-YC sub-units in grain amaranth (Amaranthus hypochondriacus) was carried out based on the bioinformatics approaches. Firstly, a total of five members of the NF-YC sub-units was reported in the grain amaranth. Its structural analyses revealed that the NF-YC sub-units were variable in physic-chemical properties, like protein sizes, molecular masses, isoelectric point, instability index, and grand average of hydropathy. Of our interest, the expression profiles of genes encoding NF-YC sub-units in various tissues\organs during the growth and development of grain amaranth. We found that three genes, including AhNF-YC01, AhNF-YC04, and AhNF-YC05 were highly expressed in leaf, root, floral, immature seed, and stem tissues. Interestingly, AhNF-YC05 was exclusively expressed in leaf and stem tissues. Taken together, our study could provide a solid understanding for further functional characterization of genes encoding NF-YC sub-units in grain amaranth.
Comparison of the Effective Atomic Numbers of Some Contrast Agents Compounds Used in Medical Imaging
Authors: KAVUN Yusuf
Published: December 2021

Contrast agents are frequently used in medical imaging such as computed tomography (CT) and magnetic resonance (MR) to reveal the final state of the body or organs. The states of the organs examined are obtained according to the absorption principle of x or gamma rays interacting with contrast agents. In this study, C17H22I3N3O8 (Iopamidol), C11H9I3N2O4 (Diatrizoic acid), BaSO4 (Barium sulfate) and C7H6O2 (Benzoic acid) compounds are examined to calculate effective atomic number (Zeff). Auto-Zeff and Direc-Zeff software have been used for calculation in an energy range from 100 keV to 10 MeV. According to the calculation results obtained have been compared with each other for each compound. According to these results, it was seen that the results were compatible with each other in low energy regions.
The Effect of Different Doses of Fluopyram on the Kidney Tissues of Mice
Authors: ÖZGÖÇMEN Meltem , TOĞAY Vehbi Atahan
Published: December 2021

Fluopyram is a widely used new generation broad spectrum fungicide and its toxic effects are mostly unknown. In this study, it was aimed to observe the effect of fluopyram administration at different doses on mouse kidney tissues. 0.5, 1 and 2 mg/kg Fluopyram were administered to mice, their kidneys were taken and evaluated histopathologically and immunohistochemically. Hematoxylin-eosin staining and also immunostaining with caspase-3, TNF-α, NF-Kb antibodies was performed. When the control group and fluopyram administered groups were compared, significant differences were found (p
Prevalence, incidence and outcome of periodontal diseases among the elderly
Authors: Al Subait Abeer Abdulrahman , Saidi Khadijah Mustafa , Alsagoor Hussain Hadi , Alrasheedi Naif Mayouf , Alanazi Asma Gadan , Alfattany Redwan Jamalaldeen , Alshammari Hatim Marzouq , Alshehri Shahad Amer , Alfaifi Asma Ali , Alosaimi Omar Obaid , Samargandi Azhar Abdullah
Published: December 2021

When compared to adults, older persons have a higher prevalence and incidence of periodontal diseases. The prevalence of periodontitis is substantially greater in the geriatrics group, which is 75 years old on average, compared to those who are 60 years old on average. Periodontitis can lead to tooth loss if natural periodontal therapies are not used. Periodontitis is the sixth most frequent incurable illness in the world, characterized by bacterial-induced and host-mediated deterioration of both soft and hard structures around the teeth. A severe type of periodontitis affects around 10% of the world's population. Periodontitis is more frequent in adults because of its chronic and debilitating nature, with around 66% of the 65-year-old age group in the United States afflicted by chronic periodontitis. A critical component of a successful disease prevention and health promotion trajectory is having up-to-date information on demographics, clinical symptoms, and illness burden on individuals, particularly in underrepresented regions where preventive programs are targeted and executed. As a result, the purpose of this paper is to evaluate the existing research on the prevalence, incidence, and consequences of periodontal diseases in the older population.
AN EVALUATION OF REAL EFFECTIVE EXCHANGE RATE FORECASTING WITH ARCH AND GARCH MODELS: THE CASE OF TURKEY
Authors: VERBERİ Can
Published: December 2021

The globalization emerging in the post-World War II increases the integration of microeconomic economic players into the international trade and financial system. Hence, exchange rates gain importance for economic decision-making. The dismissal of the Bretton Woods agreement in 1973 caused governments to implement the flexible exchange rate regime. Therefore, reliable exchange rate forecasting has importance for developing countries having structural problems and underdeveloped financial systems. Moreover, reliable exchange rate forecasting is more complicated during the Covid-19 pandemic. This study aims at investigating the real effective exchange forecasting in the Covid-19 pandemic (2019M12-2021M08) by comparing the forecast power of ARCH and GARCH models. The analysis findings demonstrate that ARIMA(1,1,1) - ARCH(2) and ARIMA(1,1,1) - GARCH(2,1) models have a slight difference and are the best models for forecasting accuracy. According to the findings, the policy-makers and microeconomic players must decide on the ARIMA(1,1,1) - GARCH(2,1) model for real effective exchange rate forecasting during the Covid-19 pandemic.
YEME BOZUKLUĞUNA İLİŞKİN KORKULAR ÖLÇEĞİNİN TÜRKÇE GEÇERLİK VE GÜVENİRLİK ÇALIŞMASI
Authors: KAHRAMAN Süleyman , KERİMLER Alara
Published: December 2021

Yeme bozuklukları, olumsuz veya düzensiz, duygular ve duygulanımın eşlik ettiği ciddi psikiyatrik hastalıklardır ve birçok psikiyatrik rahatsızlık ile komorbid seyretmektedir. Anksiyete bozuklukları da yeme bozukluklarında en yaygın görülen komorbidelerden biridir; ancak yeme bozukluğuna ilişkin spesifik korkulara ulaşma yöntemleri yetersizdir. Bu amaçla, yeme bozukluklarında görülen korkuları ölçmede kullanılabilecek Yeme Bozukluğuna İlişkin Korku Ölçeği (YBKÖ) geliştirilmiştir. Bu çalışmanın amacı bu ölçeğin Türkçe formunun geçerlik ve güvenilirlik çalışmasını gerçekleştirmektedir. Araştırmanın verileri 406 yetişkin katılımcıdan toplanmıştır. Veri toplama aracı olarak Demografik Bilgi Formu, Yeme Bozukluğu’na İlişkin Korku Ölçeği, REZZY Yeme Bozuklukları Ölçeği ve Sağlık Anksiyetesi Ölçeği kullanılmıştır. Uyarlama çalışmasında önce geçerlik ve güvenirlik incelenmiştir. Geçerlik incelemesi için SPSS üzerinden açıklayıcı faktör analizi (AFA) ve AMOS üzerinden doğrulayıcı faktör analizi (DFA) gerçekleştirilmiştir. Ana bileşenler analiziyle, ölçeğin faktörleri incelenmiştir. Örneklem büyüklüğü yeterliliği için Kaiser-Meyer-Olkin (KMO) değeri hesaplanmıştır. Ayrıca ölçek maddelerinin analize uygunluğunu belirlemek için Barlett’s küresellik testine bakılmıştır. Güvenirlik analizleri için eşdeğer test korelasyonuna ve Cronbach Alfa katsayısına bakılmıştır. Elde edilen bulgulara göre YBKÖ’nün yeterli geçerlik ve güvenirlik özelliklerine sahip olduğu bulunmuştur. Ölçeğin üç faktörlü olduğu ve toplam varyansın % 71.543’ünü açıkladığı sonucuna varılmış ve Cronbach’s Alfa iç tutarlılık katsayısı .943 olarak hesaplanmıştır. YBKÖ’nin Türkiye’de kullanılabilecek geçerli ve güvenilir bir ölçme aracı olduğuna ulaşılmıştır.
Diretrizes para o uso de entrevistas semiestruturadas em investigações científicas
Authors: Guazi Taísa Scarpin
Published: December 2021

Objetivo. Sistematizar diretrizes a respeito da utilização da técnica de entrevista semiestruturada em estudos científicos. Desenvolvimento. A técnica de entrevista foi dividida em seis etapas (elaboração e testagem do roteiro de entrevista; contato inicial com os participantes; realização das entrevistas; transcrição das entrevistas; análise dos dados e relato metodológico) e foram apresentadas recomendações em relação a cada uma delas. Demos especial destaque para as etapas de transcrição e de relato metodológico das entrevistas, visto que, em geral, são etapas negligenciadas tanto em estudos que empregam essa técnica quanto em trabalhos que especificam diretrizes para a sua utilização. Implicações. As diretrizes arroladas podem ser especialmente úteis para alunos de pós-graduação e para investigadores que não têm familiaridade com a técnica de entrevista semiestruturada. Nossas recomendações, no entanto, não contemplam particularidades de entrevistas de outras naturezas.Palavras-chave. Técnica de coleta de dados; Entrevista semiestruturada; Transcrição; Produção científica.Guidelines for the use of semistructured interviews in researchAbstractObjective. Systematize guidelines regarding the use of the semistructured interview technique in scientific studies.Development. The interview technique was divided into six stages (preparation and testing of the interview guide; initial contact with the participants; conducting the interviews; transcription of the interviews; data analysis and methodological reporting) and recommendations were presented in relation to each one of them. The steps of transcription and methodological reporting of the interviews were highlighted, because, in general, they are neglected steps both in studies that use this technique and in works that specify guidelines for its use.Implications. The guidelines listed can be especially useful for graduate students and researchers who are unfamiliar with the semistructured interview technique. Our recommendations, however, do not contemplate particularities of other types of interviews.Keywords. data collection technique; semistructured interviews; transcription; scientific production.
Seasonal-To-Interannual Variability of Sea-Surface Temperatures in The Inter-Americas Seas: Pattern-Dependent Biases in The Regional Ocean Modeling System
Authors: Caicedo Laurido Ana Lucia , Muñoz Solórsano Ángel G. , Chourio Xandre , Tobar Mosquera Cristian Andrés , Latandret Sadid
Published: December 2021

The Inter-Americas Seas (IAS), involving the Gulf of Mexico, the Caribbean and a section of the eastern tropical Pacific Ocean bordering Central America, Colombia and Ecuador, exhibits very active ocean-land-atmosphere interactions that impact socio-economic activities within and beyond the region, and that are still not well understood or represented in state-of-the-art models. On seasonal-to-interannual timescales, the main source of variability of this geographical area is related to interactions between the Pacific and the Atlantic oceans, involving to anomalous sea-surface temperature (SST) patterns like El Niño-Southern Oscillation (ENSO), and regional features in the Caribbean linked to the bi-modal seasonality of the Caribbean Low-Level Jet. This study investigates seasonal-to-interannual IAS surface-temperature anomalies in observations, and their representation in am eddy-permitting, 1/9o-resolution simulation using the Regional Ocean Modeling System (ROMS), interannually-forced by the Climate Forecast System Reanalysis. Here, rather than analyzing model biases locally (i.e., gridbox-by-gridbox), a non-local SST pattern-based diagnostic was conducted via a principal component analysis. The approach allowed to identify magnitude, variance and spatial systematic errors in SST patterns related to the Western Hemisphere Warm Pool, ENSO, the Inter-American Seas Dipole, and several other variability modes. These biases are mainly related to errors in surface heat fluxes, misrepresentation of air-sea interactions impacting surface latent cooling in the Caribbean, and too strong sub-surface thermal stratification, mostly off the coast of Ecuador and northern Peru.
Mhpm Solution to Mhd Fluid Flow Through Porous Medium with an Exponentially Variable Permeability
Authors: Silva Roberto , English English , Español Español , Español Español , Español Español
Published: December 2021

This article involves the study and analysis of the fully developed flow of a magnetorheological fluid through a non-isotropic porous medium under the effect of an external, uniform, and transversal magnetic field. Permeability is taken as an exponential distribution function of the transverse direction. The Darcy-Brinkman-Lapwood-Lorentz equation for the fluid flow in porous media has been used and solved under non-slip boundary conditions by Modified Homotopy Perturbation Method and the results validated by the Numerical Shooting Method. Finally, the analysis of results is made of the influence on the velocity, volumetric flow, and wall shear stress.
Tu materia es la confluencia de todas las cosas
Authors: Navarrete Sitja Francisco
Published: December 2021

Tu materia es la confluencia de todas las cosas consiste en un texto poético y ensayo visual. Busca reflexionar sobre el impacto de la categoría de ‘lo natural’ y simbolismos atribuidos a diferentes expresiones geológicas y atmosféricas, en la construcción de los imaginarios territoriales, estrategias de homogeneización y limitaciones que constituyen la identidad nacional en Chile.
I am a plant! Not a human being!
Authors: González Mote Ana Elizabeth , Leyva Vázquez Ingrid
Published: December 2021

En el presente texto, compartimos el proceso creativo y de investigación, en el que nuestra colectiva “Aliens Anyways” -formada por Ingrid Leyva y Ana Mote- plantea un trabajo colaborativo que explora la relación que existe entre -cuerpos, frontera y cruce-; desde la región fronteriza situada en Estados Unidos y México, específicamente entre Cd. Juárez, Chihuahua y El Paso, Texas.

Nuestro análisis, que se guía por el cuestionamiento ¿Por qué ser una planta y no un ser humano? Intenta desarrollar una respuesta, que se divide en 4 secciones. La primera de ellas presenta la forma en cómo nos integramos como colectiva y desde qué fundamentos es que logramos hacer un lugar común y una pregunta; la segunda, da cuenta del contexto histórico de los cruces desde su institucionalidad, para así llegar a un panorama contemporáneo, que en la tercera parte se sitúa con el TLCAN (Tratado de Libre Comercio de América del Norte) para discutir la situación entre los cruces de cuerpos humanos y no humanos; nuestra cuarta parte se dirige al análisis del aguacate como cuerpo no humano que nos permite evidenciar el absurdo de las políticas antiinmigrantes. Por último, proponemos a modo de conclusión una serie de ideas, que trazan la reflexión del proceso colaborativo e interdisciplinario, y de los principios estéticos que sostienen las bases para la siguiente etapa de nuestra propuesta.
Un (des)intento fugitivo de (a)bordar los (des)bordes
Authors: Barone Zallocco Ornela , Díaz Santiago
Published: December 2021

En el presente trabajo se han descompuesto los modos del pensar y producir conocimiento, se visibilizan todas las experiencias que conversan cuando (de)finimos posiciones onto-epistémicas (des)bordantes. Mediante una escritura mixturada de conceptos, teorías, referentes, experiencias y sensibilidades indagamos sobre los modos (des)bordantes  que afectan lxs cuerpxs, las sensibilidades múltiples de los territorios, los (con)textos extractivistas y capitalistas, las instituciones educativas y la consagrada academia. Se proponen múltiples preguntas como intento de dehiscencia de este escrito y su devenir en (quizá) posibles agencias insurgentes.
Fragmento de retratos de interseccionalidad en el Caribe: La historia de tía Cruzita
Authors: Nin Lizette
Published: December 2021

El negre en Abya Yala no sabe de dónde viene. El negre en Abya Yala no tiene historia, más que la del bote y el secuestro. El negre en Abya Yala solo sabe que no pertenece, que es una especie traída (secuestrade), rechazade por todes, y que a latigazos aprendió, que ser quien es. Este fragmento habla de una mestiza y suhistoria. Habla de cómo se replicaba el maltrato y el dolor que el colonizador y el secuestrador, perpetraron por muchos años. Esta historia habla de nosotres les hijes del secuestro, de la violación, del racismo, en una isla donde no había hacia dónde huir y donde vivimos otros dolores.