bluuebunny/crossref_metadata_2025 huggingface dataset:
The Fekete-Szegö functional and the Hankel determinant for a certain class of analytic functions involving the Hohlov operator
Authors: Srivastava Hari Mohan , Shaba Timilehin Gideon , Murugusundaramoorthy Gangadharan , Wanas Abbas Kareem , Oros Georgia Irina
Published: September 2022

In this paper, we introduce and study a new subclass of normalized functions that are analytic and univalent in the open unit disk $ \mathbb{U} = \{z:z\in \mathcal{C}\; \; \text{and}\; \; |z| < 1\}, $ which satisfies the following geometric criterion:

   \begin{document}$ \begin{equation*} \Re\left(\frac{\mathcal{L}_{u, v}^{w}f(z)}{z}(1-e^{-2i\phi}\mu^2z^2)e^{i\phi}\right)>0, \end{equation*} $\end{document}

where $ z\in \mathbb{U} $, $ 0\leqq \mu\leqq 1 $ and $ \phi\in \left(-\frac{\pi}{2}, \frac{\pi}{2}\right) $, and which is associated with the Hohlov operator $ \mathcal{L}_{u, v}^{w} $. For functions in this class, the coefficient bounds, as well as upper estimates for the Fekete-Szegö functional and the Hankel determinant, are investigated.
Improved U-Net based on cross-layer connection for pituitary adenoma MRI image segmentation
Authors: Jiang Xiaoliang , Xiao Junjian , Zhang Qile , Wang Lihui , Jiang Jinyun , Lan Kun
Published: September 2022

Pituitary adenoma is a common neuroendocrine neoplasm, and most of its MR images are characterized by blurred edges, high noise and similar to surrounding normal tissues. Therefore, it is extremely difficult to accurately locate and outline the lesion of pituitary adenoma. To sovle these limitations, we design a novel deep learning framework for pituitary adenoma MRI image segmentation. Under the framework of U-Net, a newly cross-layer connection is introduced to capture richer multi-scale features and contextual information. At the same time, full-scale skip structure can reasonably utilize the above information obtained by different layers. In addition, an improved inception-dense block is designed to replace the classical convolution layer, which can enlarge the effectiveness of the receiving field and increase the depth of our network. Finally, a novel loss function based on binary cross-entropy and Jaccard losses is utilized to eliminate the problem of small samples and unbalanced data. The sample data were collected from 30 patients in Quzhou People's Hospital, with a total of 500 lesion images. Experimental results show that although the amount of patient sample is small, the proposed method has better performance in pituitary adenoma image compared with existing algorithms, and its Dice, Intersection over Union (IoU), Matthews correlation coefficient (Mcc) and precision reach 88.87, 80.67, 88.91 and 97.63%, respectively.
An integrative pan-cancer analysis reveals the carcinogenic effects of NCAPH in human cancer
Authors: Liu Ying , Ma Xiao , Feng Linyuan , Lin Zhenhua , Zhou Xianchun
Published: September 2022

Background

Non-chromosomal structure maintenance protein condensin complex I subunit H (NCAPH) has been reported to play a regulatory role in a variety of cancers and is associated with tumor poor prognosis. This study aims to explore the potential role of NCAPH with a view to providing insights on pathologic mechanisms.

Methods

The expression of NCAPH in different tumors was explored by The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx). The prognostic value of NCAPH was retrieved through GEPIA and Kaplan-Meier Plotter databases. Tumor Immunity Estimation Resource (TIMER) and Single-Sample Gene Set Enrichment Analysis (GSEA) to search for the association of NCAPH with tumor immune infiltration. The cBioPortal and PhosphoSite Plus databases showed NCAPH phosphorylation status in tumors. Gene set enrichment analysis (GSEA) was performed using bioinformatics.

Results

Our findings revealed that NCAPH showed high expression levels in a wide range of tumor types, and was strongly correlated with the prognosis of patients. Moreover, a higher phosphorylation level at S59, S67, S76, S190, S222 and T38 site was discovered in head and neck squamous cell carcinoma (HNSC). NCAPH overexpression was positively correlated with the infiltration level of CD8+T cells and myeloid dendritic infiltration in breast cancer and thymoma.

Conclusions

The up-regulation of NCAPH was significantly correlated with the poor prognosis and immune infiltration in pan-cancer, and NCAPH could be served as a potential immunotherapeutic target for cancers.
La variante C
Authors: Bova Vincenzo
Published: September 2022

The pandemic is a watershed between a ‘before’, that was already suffering the fatigues of the crisis of the model of a Church’s religion, and an ‘after’ that cannot simply ‘resume’ spaces and times denied in the months of the most rigid lockdown in which the Government had imposed, and willingly accepted by the hierarchies of Catholic Church, the cancellation of any activity in presence. The pandemic has imposed itself as a total social fact and this characteristic asks for a broader reflection on some issues that have more to do with the presence in society of the Church and not just with a simple resuming of ordinary religious functions and services. There are consequences on the sacramental practice, on the community dimension and on the public relevance of the Italian Catholic Church.
Nutritional Labelling and Purchase Intention
Authors: Medina-Molina Cayetano , Alonso-Hernando Alicia
Published: September 2022

With the aim of preventing malnutrition, it has been proposed to provide information to consumers about the nutritional content of food using labelling on packages to promote healthier eating habits. Since the way in which the consumer uses the information available in the choice of healthy foods is not clear, this article aims to analyze the interrelationship between the different types of interpretative FOP labelling and the characteristics of consumers in the food purchase intention. Food purchase intention, or its negation, is determined by different combination of conditions were perceived healthiness plays an important role. Nutrition summary indicator labelling interacts with the nutrient-specific nutritional labelling, nutrition consciousness, perceived healthiness, age, and gender in different ways to determine purchase intention or negation of purchase intention. Governments must make additional efforts to ensure that the Nutri-Score guides citizens in making healthy food choices.
Combating Drug Counterfeiting by Tracing Ownership Transfer Using Blockchain Technology
Authors: Bali Vikram , Khanna Tejaswi , Soni Pawan , Gupta Shivam , Chauhan Shivi , Gupta Shivani
Published: September 2022

Supply chain management in healthcare sector plays significant role in the lives of people. Presence of intermediaries and lack of traceability has lured it towards drug counterfeiting, which reduces drug efficacy, thus hampering patients' trust and putting their lives in danger. Blockchain has emerged as a groundbreaking technology which provide a system that is immutable and transparent without the requirement of a trusted third party. This paper depicts how blockchain can provide a solution to reduce drug counterfeit in the pharmaceutical supply chain. This is achieved by creating a Blockchain Network in which each participant and the drug is registered to maintain transparency of transactions among all the participants. Realtime transfer of ownership in the blockchain creates all-round visibility among the registered participants to retrieve information like the current owner, timestamp of ownership transfer and authenticity of drugs. This paper implements PharmaChain for real-time traceability and trackability information of drugs from end-to-end of the pharmaceutical supply chain.
Biallelic mutations in WDR12 are associated with male infertility with tapered-head sperm
Authors: Hua Juan , Guo Lan , Yao Yao , Hu Wen , Wan Yang-Yang , Xu Bo
Published: September 2022

Teratozoospermia is a rare disease associated with male infertility. Several recurrent genetic mutations have been reported to be associated with abnormal sperm morphology, but the genetic basis of tapered-head sperm is not well understood. In this study, whole-exome sequencing (WES) identified a homozygous WD repeat domain 12 (WDR12; p.Ser162Ala/c.484T>G) variant in an infertile patient with tapered-head spermatozoa from a consanguineous Chinese family. Bioinformatic analysis predicted this mutation to be a pathogenic variant. To verify the effect of this variant, we analyzed WDR12 protein expression in spermatozoa of the patient and a control individual, as well as in the 293T cell line, by Western blot analysis, and found that WDR12 expression was significantly downregulated. To understand the role of normal WDR12, we evaluated its mRNA and protein expression in mice at different ages. We observed that WDR12 expression was increased in pachytene spermatocytes, with intense staining visible in round spermatid nuclei. Based on these results, the data suggest that the rare biallelic pathogenic missense variant (p.Ser162Ala/c.484T>G) in the WDR12 gene is associated with tapered-head spermatozoa. In addition, after intracytoplasmic sperm injection (ICSI), a successful pregnancy was achieved. This finding indicates that infertility associated with this WDR12 homozygous mutation can be overcome by ICSI. The present results may provide novel insights into understanding the molecular mechanisms of male infertility.
E-Learning through an Adaptive cMOOC: Is it Worthy of Further Research?
Authors: El Emrani Soumaya , Palomo-Duarte Manuel , Mota José Miguel , Dodero Juan Manuel
Published: September 2022

This paper describes the types of MOOC considered by researchers, and highlights the latter’s focus on Connectivist MOOC. In addition, it analyses MOOC methodologies, and learners’ interest in MOOC based on the concepts of adaptability, connectivism, and socio-constructivism. This is to address the high dropout rate issue on MOOC platforms. The main objective of this work is to review the empirical results reported in these studies. To reach this goal, a Systematic Literature Review of 798 papers was carried out from 2013 until April 2021, where 446 papers were selected as primary studies. The results obtained from the classification and the analysis of the collected data confirmed the importance of continuing research in the field. Based on the concepts of socio-constructivism and adaptability, the objective is to provide an adaptive cMOOC for the profile and the needs of each learner; blending learning styles and pedagogical models with machine learning technologies.
New Onset Diabetes in an Older Patient: An Unforeseen Phenomenon
Authors: Charles Creaque V. , Robinson Keilon , Santillan Sharmaine
Published: September 2022

In this case, an 86-year-old man with a history of recurrent urinary tract infections (UTIs) is brought to the emergency room with altered mental status (AMS) and frequent falls. According to the patient's son, the patient had a significant decline and became more dependent in both
his regular and instrumental activities of daily living. Upon admission, the patient was found to be in a hyperosmolar hyperglycemic state and eventually diagnosed with diabetes. A review of the patient’s medications indicated that polypharmacy may be a contributing factor to his current
mental status changes and falls. In addition, this case reviews the diagnosis of diabetes in an 86-year-old while reviewing the impact of polypharmacy in an older patient.
Role of Pimavanserin Treatment-Continuity on Discharge From Long-term Care: Assessing the Quality of Antipsychotic Medication Review
Authors: Rajagopalan Krithika , May Damian , Worz Chad , Hernandez Stephanie , Doshi Dilesh
Published: September 2022

Objective: To investigate the role of (1) antipsychotic medication review (AP-MR) documentation quality of Minimum Data Set 3.0 (MDS) surveys, and (2) treatment-continuity on discharge-to-community and clinical outcomes among long-term care (LTC) residents treated with pimavanserin.
Design, Setting, and Participants: A retrospective cohort analysis of Parts A, B, and D claims from Medicare 100% sample merged with MDS data from June 2016 through December 2018 was conducted. Residents with more than 100-day LTC stay and 1 pimavanserin prescription or more
with completed antipsychotic-use MDS question were selected. AP-MR documentation quality (ie, gradual dose reduction [GDR] attempts, clinical contraindication to GDR), discharge-to-community, and clinical outcomes (eg, falls, fractures) were obtained from MDS. Treatment-continuity was assessed
from Part D claims. Data Analysis: Descriptive statistics (frequencies, proportions, Chi-square tests, and means) and adjusted logistic regressions (ORs with 95% CIs reported association between pimavanserin treatment-continuity and discharge-to-community. Results:
Of 4,021 eligible residents, 29% (n = 1,182) attempted a GDR per AP-MR MDS documentation. Approximately 41% (n = 1,665) had documentation showing GDR was clinically contraindicated, yet 39% (n = 645) still attempted GDR. While overall discharge-to-community rates were low, it was significantly
higher (P < 0.05) among LTC residents continuing (14.94%; n = 380/2,546) versus discontinuing (11.84%; n = 171/1,444) pimavanserin. OR for treatment-continuity was 1.96, 95% CI 1.50-2.55. Residents continuing pimavanserin had lower incidents of falls (2.8% vs 9.4%), hip fractures
(0.29% vs 0.69%), and pelvic/femur fractures (0% vs 0.92%) versus those residents who discontinued it. Conclusions: Among LTC-stay residents, high discordance between GDR rates and AP-MR MDS documentation quality was observed. Pimvanserin treatment-continuity showed greater
likelihood of discharge-to-community; continued documentation training can ensure appropriate antipsychotic use with a balanced benefit:risk profile.
Loss of p16 expression is a risk factor for recurrence in sinonasal inverted papilloma
Authors: Menéndez del Castro M. , Naves Cabal V. , Vivanco B. , Suárez-Fernández L. , López F. , Llorente J.L. , Hermsen M.A. , Álvarez-Marcos C.
Published: September 2022

Background: The purpose of this study was to evaluate p16, p53, EGFR, pEGFR protein expression and HPV infection as possible markers of tumor progression in a series of sinonasal inverted papilloma (SNIP) and sinonasal squamous cell carcinoma (SNSCC). Methods: A series of 49 SNIP, 11 SNSCC associated with SNIP (SNIP-SNSCC) and 52 SNSCC not associated with SNIP were analyzed for p16, p53, EGFR, and phosphorylated EGFR (pEGFR) expression by immunohistochemistry. Human papillomavirus (HPV) infection status was evaluated by DNA-PCR. Results were correlated to clinical and follow-up data. Results: Reduced or loss of p16 expression was observed in 18% SNIP, 64% SNIP-SNSCC and 87% of SNSCC. Reduced or loss p16 staining in SNIP correlated with shorter recurrent SNIP-free follow-up. In contrast, p16 expression was not predictive of recurrent SNSCC in cases with SNIP-SNSCC and SNSCC. P53, EGFR, and pEGFR expression did not differ between the tumor groups, nor were they related to recurrent SNIP-free follow-up or recurrent SNSCC. Oncogenic HPV types 16 and 18 were detected in 5% of SNIP and 18% of SNIP-SNSCC, but not in SNSCC. There was no correlation between HPV infection and >70% p16 immunostaining. Conclusions: HPV infection appears to play a minor role in SNIP and SNSCC and p16 immunostaining does not appear a valid surrogate marker for HPV. However, reduced or loss p16 expression may have prognostic value as a risk marker for recurrent SNIP.
Tit Livij: Od ustanovitve mesta
Authors: Simoniti Primož
Published: September 2022

Že od vsega začetka je dobro znano, da so se po padcu Troje Ahajci surovo znesli nad preživelimi Trojanci, samo proti dvema, Eneju in Antenorju, so se zaradi starega gostinskega prijateljstva in ker sta se zmeraj zavzemala za mir in vrnitev Helene, odpovedali slehernemu vojnemu pravu. Nato je po raznih nezgodah Antenor z množicoEnetov, ki so bili zaradi upora pregnani iz Paflagonije in so, ker so pred Trojo izgubili kralja Pilajmena, iskali voditelja in bivališče, prišel v najbolj notranji zaliv Jadranskega morja. Eneti in Trojanci so pregnali Evganejce, ki so prebivali med morjem in Alpami, in zasedli njihovo ozemlje. Kraj, kjer so najprej stopili na kopno, se imenuje Troja in po njem so poimenovali Trojanski okraj. Vsemu ljudstvu je ime Veneti.
Francesco Petrarca: Pisma prijateljem
Authors: Božič Anja
Published: September 2022

Ko sem prenočeval v predmestju Vicenze, sem se domislil nove snovi za pisanje. Naneslo je namreč, da sem po opoldanskem odhodu iz Padove vrata tvojega mesta dosegel, ko se je sonce že nagibalo k zahodu. Preudarjal sem, ali naj prenočim tam ali naj nadaljujem pot – kajti mudilo se mi je, hkrati pa mi je zaradi dolžine dneva ostal še dobršen del svetlih ur – in ko sem se tako obotavljal, – glej – kdo bi se mogel skriti pred prijatelji? – si mi s svojim  predragim prihodom v družbi imenitnih mož, kakršnih je to drobno mestece rodilo na pretek, odgnal vsak dvom. Kot bi mi z nitjo prijetno pestrega pogovora pričvrstil omahujočega duha, sem kljub misli na odhod ostal in šele ko se je spustila noč, sem zapazil, da je dan spolzel mimo. Kot že mnogokrat poprej sem tudi tistega dne spoznal, da nam nič drugega ne izmika časa tako neopazno kot prav pogovori s prijatelji. Prijatelji so spretni tatovi časa, čeprav nobenega časa – razen tistega, ki ga posvetimo Bogu – ne bi smeli šteti za manj ukradenega, za manj izgubljenega, kot tistega, ki ga preživimo s prijatelji.
Çevresel Etkileri Bakımından Bazı Mineral Beton Katkı Maddelerinin Ga, Ag ve B İçeriklerinin Değerlendirilmesi
Authors: Şevik Hakan , Ibrahim Elajail Ibrahim Saleh
Published: September 2022

Son yüzyılda dünya genelinde nüfus artışı ve nüfusun kentsel alanlarda yoğunlaşması, kentsel alanlarda yeni binaların yapılmasını zorunlu kılmıştır. Bu binalar büyük oranda betonarme binalar olup, temel yapıtaşını beton oluşturmaktadır. Beton ise çeşitli katkı maddelerinin bileşiminden oluşmaktadır. Günümüzde betonun yoğun kullanımından dolayı beton katkı maddeleri konusunda çok sayıda çalışma yapılmaktadır. Ancak, bu katkı maddelerinin kimyasal içerikleri konusunda yapılmış çalışma sayısı oldukça sınırlıdır. Bu katkı maddelerinin kimyasal içerikleri konusunda önemli bilgi eksikliği bulunmaktadır ve bu durum sektörde çalışan insanların sağlığı yanında inşaat faaliyetlerinin çevresel etkileri konusunda da bilgi eksikliği oluşmasına sebep olmaktadır.

Bu çalışmada, beton katkı maddesi olarak kullanılan bazı malzemelerde, insan ve çevre sağlığı açısından son derece zararlı olan ağır metallerden Ga, Ag ve B konsantrasyonları değerlendirilmiştir. Çalışma sonuçları özellikle bazı çimentolar ile yüksek fırın cürufu ve bakır cürufu gibi bazı katkı maddelerinde çalışmaya konu ağır metallerden Ga konsantrasyonunun 236,139 ppm’e, Ag konsantrasyonunun 7401,9 ppb’ye ve B konsatrasyonunun da 1390,689 ppm’e kadar çıkabildiği belirlenmiştir. Bu durum, sektörde çalışan kişiler ile çevre sağlığı açısından büyük risk teşkil edebilir.
Comparison of Face-to-face and Online Computer Science Education in High School
Authors: Coufal Petr
Published: September 2022

This study focuses on the analysis of regular face-to-face computer science instruction with online instruction in high school. Given the modernization of conventional teaching in schools, it would be a good idea to keep some elements of online teaching and allow students to learn remotely. What are the benefits of online learning on the development of students and their competencies? As part of the research investigation, we experimented with and compared the learning achievement of two groups of students in the subject of computer science. The first group was taught normally full-time at school, while the second group was taught online at home. As part of the research investigation, we compared their academic achievement in different areas of computer science and STEM (Science, Technology, Engineering, Mathematics), ranging from programming to working with robots. The results of the published research do not confirm statistical differences between online and face-to-face teaching. It follows that the different form of teaching does not affect the development and evaluation of the student and his academic achievements.
A CLINICAL STUDY ON EKAKUSTHA(PSORIASIS) AND IT’S MANAGEMENT BY VAMANA KARMA AFTER TAKING OF PANCHAKOLA & SNEHAPANA
Authors: Mukherjee Pallabi
Published: September 2022

Psoriasis is a non infectious chronic relapsing inflammatory skin diseases characterized by well defined dry scaly erythmatous patches & covered with adherent silvery white scales. Psoriasis can be correlated with “Ekakustha” in Ayurveda .Ekakustha is predominated with Vata & kafa dosa.The symptoms of Ekakustha -Aswedana {not perspire) ,mahavastu(extensive), masyasokolapama(looks like fish scale) and Arun barna(discolouration).In this clinical study 50 patents of psoriasis are selected according to inclusion & exclusion criteria. The total patients have been divided into three groups. Group A has been treated with “Panchakola powder’ (3 gm thrice before meal for 7 days); Group B patents have been treated by ‘Mahatiktak Ghrita”(as scheduled dose of snehapana up to samyak sneha lakshana is appeared 3-7 days);And Group C patients have been treated with Powder Panchakola +Mahatikta ghrita +Vamana karma (by Modan phala powder + Vacha pow +Saindhav lavana along with madhu & Yasthimadhu kwath),After administration of drugs & therapy the percentage of relief of Group A-Matsyasokolapama(55.83%), Rukhsata(53%), Arunattwa(50%), kandu (50%).In Group B patients after application of Panchakola + Mahatiktak Ghrita the percentage of relief Matsyasokolapama(42%), Rukhsata(58%), Arunattwa(42.5%) Kandu(40.82%)..And after administration of Panchakola powder +Mahatikta ghrita + Vamana in Group C patients the percentage of relief –Matsyasokolapama (67.78%) ,Rukshata(64.8%), Arunattwa(65.35%) kandu(72.01%).
IMPORTANCE OF SAMPRATI IN KRIMIVIKAR
Authors: Gandhe Dr Shankarprasad , Naikodi Dr Dnyneshvar , Jadhav Dr Avinash
Published: September 2022

Charaka and Vagbhatta have diferentiated Abhyantara Krimis into three types as Shleshmaja, Purishaja and Raktaja. According to them they are seven types of Shleshmaja Krimis. They have also mentioned their morphology.
KRIYAKALPA – A GLIMPSE OF NETRAROGAS
Authors: Nakshane Indrayani , Virkar Chandana
Published: September 2022

Kriyakalpas, the specialized ocular treatment modalities, affirms the absolute necessity of unique approach towards netrarogas, thus highlighting the gravitas of eye and eye diseases .Many procedures and formulations have been described to cure the ophthalmic disorders. Present conventional system of medicine has topical and systemic administration of drugs to the eye which are highly inefficient and there is a need for controlled, sustained release, particularly for conditions that affect all parts of the eye. Sushruta, the father of ancient Indian surgery, advocated ‘Kriyakalpa’ is the main therapeutic procedure for Netra Rogas, along with other forms of treatment. He has described this in a separate chapter in Uttartantra of Sushruta Samhita .These procedures improve the vision by strengthening of the cilliary muscles, maintaining unctuousness of the eye ball, proper accommodation of the lens, delays the senile opacity of the lens etc. On the other hand these procedures also helpful in dealing with inflammatory conditions like conjunctivitis, hordeolum, corneal ulcer, staphyloma, panophthalmitis etc. Thus Kriyakalpa can be done in healthy as well as diseased eye conditions to improve the ophthalmic health. The probable mode of action and possible drug route of Kriyakalpas are yet to be explored
A CASE STUDY OF APPENDICITIS WITH MIKEL’S DIVERTICULUM
Authors: Gaikwad Dr. Amarja Atmaram , Banarase Dr. Mrs. Madhavi S.
Published: September 2022

An appendectomy is one of the most commonly performed abdominal surgical procedures. During this operation, a Meckel's diverticulum (MD) can occasionally be found as an incidental finding, but the coexistence of both appendicitis and a MD is fairly rare. Complications associated with an MD commonly occur in males, but the frequency of complications decreases with aging. Here, we present a rare case with a simultaneous coexistence of appendicitis and MD in a patient.When Meckel's diverticulum is suspected or diagnosed, patients should be surgically treated to prevent any complications to the patient.
IMPACT OF COVID-19 ON DENTAL HYGIENIST STUDENTS IN SAUDI ARABIA
Authors: ALANAZI MARYAM , ALSIWA AREEJ JABER
Published: September 2022

Objectives:This study aims to evaluate the impact of COVID‐19 on dental hygienist student trainee in Saudi Arabia. And To explore the phycological impact as well as assess the quality of learning process among dental hygiene students.Methods:Online survey will administrate to dental hygienists (students in level5-6 & 7-8 ) as well as internships students. The survey includes questions about student demographics, student perceptions of institutional responses, student concerns, and psychological impacts.Result:The study recruited 61 participants in total from 4 different universities in the country. The results alsoshowed that the students had a high level of concern for their safety from the pandemic’s infection. They generally believed that they were at higher risk of infection from the patient population than those of their colleagues and staff with whom they will interact within their classes and across university buildings.Conclusion:more needs to be done to help students adjust to the impact of the pandemic by restoring their faith in the educational system through dialogue and a collaborative approach to improve the level of education provided within the educational system. The government should also show that there are concrete plans to support the economy and future job prospects of medical students in the country.
La teología del laicado y su praxis. Responsabilidad moral ante el “don” y la “misión”
Authors: Pardo Manrique Román Ángel
Published: September 2022

En este artículo se presenta una breve introducción a la historia de la «teología del laicado». Posteriormente se analiza la situación actual del laico en la Iglesia del siglo XXI para terminar con unas pistas para la acción y participación del laicado en la vida pública y en la misión de la Iglesia.
La desigualdad a domicilio: el trabajo remunerado del hogar en el Ecuador contemporáneo
Authors: Casanova Erynn Masi de
Published: September 2022

En La desigualdad a domicilio, Erynn Masi de Casanova enriquece con nuevas facetas los estudios de género en el Ecuador del siglo XXI. Anclándose en el concepto de reproducción social y combinándolo con otros dos –el empleo informal urbano y la clase social–, la autora ilumina las formas particulares de explotación económica a las trabajadoras del hogar y explica por qué este trabajo remunerado es un mal trabajo. Las tareas de cuidado y el trabajo doméstico están a cargo principalmente de las mujeres. Cuando son remuneradas, quienes las realizan comparten con sus empleadores el espacio íntimo del hogar, invariablemente cruzado por los afectos. En este contexto, las formas de dominación se personalizan y se desdibujan los rasgos propios de los empleos en el ámbito productivo. La autora se alimenta de las perspectivas y problemas planteados por las propias trabajadoras del hogar, con el objetivo de ofrecer información tanto a quienes defienden sus derechos como a quienes diseñan las políticas de empleo. Simultáneamente, a través de un diálogo con la comunidad académica de América Latina, inserta el caso de Ecuador en la reflexión sobre el trabajo remunerado del hogar en la región. En este libro se demuestra que la condición de las trabajadoras del hogar no cambiará mientras la reproducción social esté devaluada frente a la producción de bienes, los arreglos laborales informales prevalezcan y se mantenga una tajante división de clase entre las trabajadoras y quienes las contratan.
Facetas del Miedo:
Authors: De la O Torres Rodrigo
Published: September 2022

El 26 de noviembre de 1565 el procurador de Yucatán, Joaquín Leguisamo, condujo la realización de una información para exponer el peligro en el que estaba la provincia gracias a la presencia y actividad de corsarios franceses. Nuestro propósito es analizar este documento para dar cuenta de los entrelazamientos suscitados entre el fenómeno de la piratería y la gobernación yucateca. Para ello, planteamos una historia cultural del miedo que atienda: la definición de corsario como origen de afectaciones; la ubicación de esa otredad peligrosa en el Golfo-Caribe y su cercanía a la península de Yucatán; las vulnerabilidades y un entorno de inseguridad, ambos procedentes del temor a la pérdida de Yucatán ante una invasión de corsarios. Estas dimensiones permiten un acercamiento tanto al impacto del fenómeno de la piratería en la provincia como las formas en que las autoridades coloniales dieron sentido a aquel.
Voces de excombatientes al final de una guerra:
Authors: Sanandres Eliana , Molinares-Guerrero Ivonne
Published: September 2022

El objetivo de este artículo es conocer las experiencias de interacción vividas por excombatientes de las FARC-EP con los miembros del cuerpo policial al final de la confrontación armada. Se realizó un estudio de caso en el que participaron 17 excombatientes a través de una entrevista semiestructurada. Los resultados del estudio revelan sus percepciones, emociones y acciones compartidas alrededor de cuatro categorías centrales: Respeto a las diferencias, Miedo y desconfianza, Identificación con el adversario y Redefinición del enemigo. Estos resultados permiten dilucidar una perspectiva de reconciliación desde la construcción de relaciones sociales y pistas para promover un escenario de país diferente al que dejó el conflicto con las FARC-EP en Colombia.
Simbolismo, poder eclesiástico y luchas políticas tras una corona pontificia:
Authors: Fonseca Ramírez Cristina
Published: September 2022

La Iglesia mexicana, a mediados del siglo XIX, se encontraba dividida en dos facciones bien delimitadas, ‘romanos’ o partidarios de la reforma religiosa implementada desde la silla papal y educados en Roma, y el clero nacional, o ‘local’, formado en seminarios mexicanos. Estos veían con recelo la centralización del poder en la figura del sumo pontífice en detrimento de los cabildos mexicanos, así como su exclusión de posiciones importantes de poder en la Iglesia mexicana. El representante de la facción romana fue Pelagio Labastida y Dávalos, figura importantísima de la política religiosa del México decimonónico, persona muy cercana a Pío IX y quien dentro de su plan trazado buscó la centralización del poder de la Iglesia mexicana en sus manos. Una de las estrategias de reafirmación de este poder fue conseguir la coronación de la Virgen de Guadalupe. Sin embargo, el proyecto se complicó por lo que los obligó, a él y a su sobrino, José Antonio Plancarte, a idear toda una estrategia alternativa religiosa, política y mediática dentro de la cual estuvo la coronación de la Virgen de la Esperanza de Jacona.
mujeres y la apariencia:
Authors: Márquez Macias Rosario
Published: September 2022

A través de estas líneas nos aproximamos, dentro de la historia de las mentalidades, a uno de los aspectos de la vida cotidiana en América: la vestimenta, y en concreto la de las mujeres, que se convirtió en signo de identidad. Cómo vestirse para demostrar honradez y status fueron los recurrentes consejos que estas mujeres recibían de sus parientes ya asentados en América. Un nuevo enfoque que nos proporciona una fuente de incalculable valor: las cartas privadas.
Caracterización de la financiación para desarrollo en Colombia (2010-2018): caso empresa ACME SA
Authors: Giraldo Cardona Ingrid , Socorro Márquez Félix , Reyes Ortiz Giovanni Efraín
Published: September 2022

La investigación se centró en una problemática de financiación, a través del análisis de los datos históricos, en un periodo de 8 años, dada la factibilidad de contar con datos comparables, de la empresa ACME SA. El objetivo principal de este estudio fue proporcionar una caracterización actualizada de las inversiones de la firma ACME SA, en función de los departamentos y regiones del país, teniendo en cuenta: (i) cada departamento de Colombia; (ii) cada región del país (Amazónica, Andina, Caribe, Orinoquía y Pacífica); (iii) departamentos conforme a cuartiles de competitividad; (iv) departamentos conforme a los cuartiles de la contribución al producto interno bruto (PIB); y, finalmente, (v) departamentos conforme a cuartiles de población. Como metodología se utilizó principalmente la técnica de regresión lineal. Con base en ello los datos fueron agrupados por sector económico y departamental para analizar la cobertura. Por lo tanto, el resultado del estudio brinda una herramienta altamente fundamentada para la toma decisiones, como lo son el direccionamiento de la estrategia para la priorización del desarrollo a través de indicadores de gran relevancia como lo son el PIB, la población y la competitividad.
Redes, conocimientos y capacidades en el contexto de la industria del software. Análisis del caso Bahía Blanca
Authors: Diez José Ignacio , Giannasi Nadia , Scudelati Mariela
Published: September 2022

En las últimas décadas ha surgido a nivel mundial un creciente interés por los fundamentos micro y meso económicos de la competitividad. Diversos autores han diseñado enfoques que buscan explicar este fenómeno a partir del desarrollo de capacidades endógenas y relacionales por parte de las empresas. Las capacidades relacionales se ejercitan en contacto con otros agentes y permiten explotar adecuadamente los conocimientos y recursos que circulan por el ámbito de las redes. El presente trabajo analiza este tipo de competencias y los vínculos que existen entre las empresas de software de la ciudad de Bahía Blanca. La metodología utilizada para el estudio de este fenómeno es el análisis de redes sociales o ARS.
Sverdlovsk Union of Soviet Artists after the war
Authors: Айнутдинов А.С.
Published: September 2022

В статье анализируется и описывается структура, творческие и идеологические задачи, организационные мероприятия и исторические события, которые определяли и сопровождали деятельность Свердловского отделения Оргкомитета Союза советских художников после окончания Великой Отечественной войны, вплоть до конца 1952 года, конца сталинской эпохи. С помощью историко-генетического и историко-сравнительного методов исследования восстанавливается объективный ход функционирования творческого союза и его первичной партийной организации в 1946–1952 годах. Выделены и охарактеризованы основные этапы их работы, акцентируется внимание на содержательных отличиях этого периода. Все использованные источники введены в научный оборот впервые.

The article analyses and describes the structure, creative and ideological tasks, organizational events and historical events that determined and accompanied the activities of the organizing committee of the Sverdlovsk branch of the Union of Soviet Artists after the end of the Great Patriotic War, up to the end of 1952, the end of the Stalin period. The author uses historical-genetic and historical-comparative research methods to restore the objective course of the functioning of the creative union and its primary party organization in 1946–1952. The result was the identified and characterized stages of their work, the author focuses on the substantive differences between these periods. For the first time, the study introduces into scientific circulation all the archival and documentary sources used here.
Sverdlovsk-Ekaterinburg marginal artists: a way out of underground art of the 1970s – 1990s
Authors: Авдеева В.В.
Published: September 2022

В статье рассматриваются положение и место непрофессиональных художников Свердловска-Екатеринбурга в последней трети XX века. Это творчество балансирующих на границах маргинальности или находящихся в ее пограничных состояниях: Валерия Гаврилова (1948–1982) и Зинаиды Гавриловой (1974–1993), Е.М. Малахина, или старика Б.У. Кашкина (1938–2005),первого поколения неофициальных художников 1970–1980-х годов; Д.П. Девятова (1968 г. р.), Л. Луговых (1964 г. р.) и других, второго поколения неофициальных художников 1980–1990-х годов. Предметом исследования стали как сами художники и их объединения, так и их творческие эксперименты с материалами, формами, мотивами. Автор находит в произведениях непрофессиональных художников стилистические параллели с классикой сюрреализма, кубизмом, конструктивизмом, наивом, аутсайдеровским искусством и творчеством представителей ар-брюта, в то же время отмечая бунтарский дух и постмодернистские эксперименты в художественно-образной интерпретации видимого мира.

The article examines the position and place of non-professional Sverdlovsk-Ekaterinburg artists in the last third of the twentieth century. These are balancing on the borders of marginality or being in its borderline states: Valery Gavrilov (1948–1982) and Zinaida Gavrilova (1974–1993), E.M. Malakhin or the old man B.U. Kashkin (1938–2005), the first generation of unofficial artists of the 1970s – 1980s; D.P. Devyatov (born 1968), L. Lugovoi (born 1964), etc., the second generation of unofficial artists of 1980s – 1990s. The subject of the study was both the artists themselves and their associations, as well as their creative experiments with materials, forms, and motifs. The author finds in the works of non-professional artists stylistic parallels with the classics of surrealism, cubism, constructivism, naive, outsider art and art brut, at the same time noting the rebellious spirit and postmodern experiments in the artistic and figurative interpretation of the visible world.
Yuriy Vysokovskikh and Yuriy Trofimov: artists of the second Russian avant-garde in Karelian art
Authors: Бахилина О.А.
Published: September 2022

Статья посвящена художникам второй волны русского авангарда в искусстве Карелии XX века. Цель — на примере знаковых произведений карельских художников Юрия Высоковских и Юрия Трофимова продемонстрировать принадлежность художников ко второй волне авангарда. В качестве методов применены историко-генетический, историко-биографический и стилистический анализ.

The article is devoted to the artists of the second Russian avant-garde in the art of Karelia of the twentieth century. The aim is to identify the iconic works of Karelian artists Yuriy Vysokovskikh and Yuriy Trofimov, confirming their belonging to the second Russian avant-garde, through such research methods as historical, biographical and stylistic analysis.
Expansion of space: continuity in the development of the idea of space-time between the first and second waves of the Russian avant-garde
Authors: Рюмина Е.А.
Published: September 2022

Цель статьи — проследить преемственность в развитии идеи и понятия пространства-времени между «первой волной» и «второй волной» русского авангарда, пользуясь методом «прибавочного элемента» К. Малевича. Развитие именно этих идей и понятий оказалось решающим для искусства всего XX века и далее, продолжая распространяться на новые его формы, включая инсталляции, перформансы и digital art. Трансформация этих идей и понятий оказалась такой же важной, как открытие в эпоху Ренессанса пространственного измерения в изображении — перспективы. Апеллируя к теоретическим работам К. Малевича, а также к философскому и научному контексту его времени и XX века, исследование демонстрирует онтологическую преемственность по существу идей первых русских супрематистов и дальнейшее развитие их сегодня. В статье эта преемственность показана на примере творчества двух живых классиков второй волны русского авангарда 1960–1970-х годов — Сергея Бордачёва и Александра Юликова. Работы обоих художников находятся в коллекциях Третьяковской галереи, Русского музея, музея Циммерли (США) и центра Помпиду (Франция).

The article aims to demonstrate the continuity in the first and second Russian avant-garde art regarding the development of the space-time concept. The general method applied in my research follows the theory of “surplus element” developed by Malevich. His ideas and concepts had become a key contribution to the art of the 20th century and continued to influence such novel artistic phenomena as installation, performance and digital art. Transformation of these ideas and concepts appeared to be equally important as the discovery of visual perspective in the art of the Renaissance. Addressing the theoretical works of Kazimir Malevich as well as the philosophical and academic context of his time and the 20th century in general, this article reveals essential ontological links between the first and second Russian avant-garde art, the ideas of the early Russian Suprematists and their evolution today. This is achieved on the example of some living classics of the second Russian avant-garde such as Sergey Bordachev and Alexander Yulikov; works by both artists are in the collections of the Tretyakov Gallery (Moscow, Russia), Saint-Petersburg Russian Museum (Russia), Zimmerli Museum (New Brunswick, USA) and Georges Pompidou Center (Paris, France).
Evaluation of the Biological Activities of Royal Jelly on Prostate and Breast Cancer Cells
Authors: AYNA Adnan , DARENDELİOĞLU Ekrem
Published: September 2022

Due to their high toxicity to healthy body cells, chemotherapy drugs used to treat cancer pose a serious threat to the organism. Recent studies have encouraged the utilization of bee products to prevent and treat the cancer. The specific food for the queen honeybee larva (Apis mellifera), royal jelly (RJ) is a yellow, milky, cremy product of the bee which is stowed from the mandibular and hypopharyngeal glands of the worker honeybee. According to the reports, RJ may have cytotoxic effects in animal models. However, RJ's cytotoxic and antioxidant properties on PC-3 prostate cancer and MCF-7 breast cancer cell lines have yet to be thoroughly investigated at the cellular level. Therefore, the antioxidant and anti-proliferative activities of RJ in PC-3 prostate cancer cells and MCF-7 breast cancer cells were evaluated to investigate a chemopreventive strategy to increase cancer therapy efficacy. WST-1 assay was used to measure cell proliferation, and levels of reactive oxygen species (ROS) and lipid peroxidation (LPO) were analyzed to look at antioxidant activities. According to the data of this research, RJ act as prooxidants in PC-3 and MCF-7 cancer cell lines by lessening cellular viability and raising ROS and LPO formation.
Synthesis and Characterization of Fmoc Group Protected Amino Acid Chalcone Conjugates
Authors: ÇALIŞKAN Eray
Published: September 2022

In this study, a series of dipeptide compounds were synthesized as a result of the reaction of Fmoc group-protected amino acids and amino chalcones with triazine reagent. The structures of the synthesized compounds were characterized by FT-IR, 1H and 13C APT NMR spectroscopy techniques. The electrical behavior of the conjugares was investigated with an impedance analyzer in the frequency range of 1-30 kHz. The variation in dielectric constant, dielectric loss, susceptibility and impedance parameters were investigated as a function of frequency. The dielectric constant of the dipeptides ranges from 7.2 to 8.6.
Doença mista do tecido conjuntivo – critérios classificatórios
Authors: Franco Andre Silva , Miossi Renata
Published: September 2022

A doença mista do tecido conjuntivo é caracterizada por combinação de achados de três outras doenças autoimunes (lúpus eritematoso sistêmico, esclerose sistêmica e polimiosite ou dermatomiosite) mais a presença do anticorpo anti-U1-RNP em altos títulos. Existem quatro critérios diagnósticos clássicos, mas ainda não há consenso sobre qual seria o melhor, assim como não há critérios exclusivos de atividade de doença ou de dano.

Unitermos: Doença mista do tecido conjuntivo. Critérios classificatórios. Critérios diagnósticos.
Profile and Outcome of Congenital Heart Disease in Buea, South West Region of Cameroon: A Cross-Sectional Study
Authors: Djike Puepi Yolande F
Published: September 2022

Background: Congenital Heart Disease (CHD) is a major cause of morbidity and mortality in children. There is scarcity of data on the profile and outcome of CHD in children in semi-urban settings in Cameroon.

Methods: A retrospective cross-sectional study was conducted from June 2016 to June 2021. The echocardiographic register was reviewed and outcome was examined.

Results: 77 children were diagnosed with a definite congenital heart disease. There were 44(57.1%) females. The median age was 4 months (IQR: 1.5-24). The most common indications for echocardiography were murmur (45.5%), cyanosis (16.9%) and cardiomegaly (10.4%) on chest X-ray. The most common CHD was isolated ventricular septal defect in 23 (29.9%) children followed by Tetralogy of Fallot in 10 (13.0%) and patent ductus arteriosus 10 (13.0%) children. Out of the 77 cases diagnosed, only 9 (11.7%) underwent complete surgery correction in France via non-governmental organizations. The others cases (68/77) were either not eligible for surgery (17/77) or needed financial support (51/77).

Conclusion: The most common CHD was ventricular septal defect and only about 1 out of 10 children with CHD underwent surgery, with all surgeries done abroad.

Keywords: Congenital Heart Disease; Neonatal Risk Factors; Out Patient Department; Pregnancy; Neonatal
Investigating the Psychosocial Dimension of Perinatality in Cameroon
Authors: Moyo Kamsu
Published: September 2022

Introduction: It is well known that events occurring during the prenatal period may affect the outcome of perinatality. Although the psychopathological theories that give account of psychological conflicts of the perinatal period are well described, these may be aggravated by a number of psychosocial factors which may vary according to context.

Methodology: We investigated some of these factors through a case-control study among Cameroonian women who manifested psychic impairments few days after delivery. The study was conducted in two university teaching hospitals of Yaoundé, over a period of six months.

Results: We observed that a number of psychosocial factors can effectively impact the quality of the perinatal period with serious maternal and neonatal repercussions. These factors are related with class distinctions, unequal distribution of wealth, health inequalities, and the poor quality of social relationships.

Conclusion: We may therefore conclude that preventing psychosocial risk factors through the reinforcement of the socioeconomic tissue and health systems may ease perinatality with favorable outcomes.

Keywords: Perinatality; Psychosocial Factors; Maternity; Postpartum