bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficient recovery of beta-mannanase fused with LysM3014 domain in Escherichia coliby glass bead based-cell disruption method
Authors:   Faculty of Chemical Engineering, University of Science and Technology, The University of Danang, 54 Nguyen Luong BangStreet, Hoa Khanh Bac Ward, Lien Chieu District, Da Nang City, Vietnam, Nguyen Hoang Minh , Phan ThiThuy Hang ,   Faculty of Chemical Engineering, University of Science and Technology, The University of Danang, 54 Nguyen Luong BangStreet, Hoa Khanh Bac Ward, Lien Chieu District, Da Nang City, Vietnam, Nguyen Thi Y Nhu ,   Faculty of Chemical Engineering, University of Science and Technology, The University of Danang, 54 Nguyen Luong BangStreet, Hoa Khanh Bac Ward, Lien Chieu District, Da Nang City, Vietnam, Le Chanh Chi Tai ,   Faculty of Chemical Engineering, University of Science and Technology, The University of Danang, 54 Nguyen Luong BangStreet, Hoa Khanh Bac Ward, Lien Chieu District, Da Nang City, Vietnam, Nguyen Ngoc Tram ,   Faculty of Chemical Engineering, University of Science and Technology, The University of Danang, 54 Nguyen Luong BangStreet, Hoa Khanh Bac Ward, Lien Chieu District, Da Nang City, Vietnam
Published: May 2024

Toward the development of whole cell biocatalysts via non-GMO strategy, in this study, three cell disruption methods (sonication, freezingand thawing and bead-shaking) have been evaluatedto recover efficiently fusion protein LysM3014-ManB containing a beta-mannanase (ManB) from Bacillus lichenifomisfused with a single LysM3014 domain derived from a putative extracellulartransglycosylase Lp_3014 of Lactobacillus plantarumWCFS1. The results showed that the highest volumetric activity of fusion protein (~46651 U/lfermentation) was obtained when shaking the recombinant E. coliwith glass bead. Moreover, the enzymatic activity of LysM3014-ManB increased approximately 1.4 folds(~66000 U/lfermentation)under the optimum conditions of glass bead-based cell disruption (falcon 50 ml, glass bead ratio of 1.0 g/mland disruption time of 8 min). The study indicates that shaking the cells with glass bead is likely to be the simplest and the most efficient cell disruption methodin comparison with other disruption methods.
Global digital identity: technology of power
Authors:   St. Petersburg State University, Morina L.P.
Published: May 2024

The report analyzes the specifics of human existence in digital culture as a manipulated identifier. The phenomenon of Homo Digital is described and the essential features and ways of funding digital identity are given. Two distinct, but interrelated, aspects of digital identity are revealed. The imperative of information-digital transcoding of traditional cultural forms and communicative practices is shown.
Trust to cultural code: situation of metamodern
Authors:   Saint Petersburg State University, Nogovitsyn Nikita
Published: May 2024

The second half of the twentieth century is often labeled as the era of postmodernity — total distrust of narratives, irony and doubt. In the context of this era, the idea of the end of history emerged, expressing the impossibility of further development of culture as a whole. Meanwhile, already at the end of the twentieth century, a large number of theories emerged indicating that history has not stopped, and culture continues to develop. One of the signs of such development is the restoration of trust in cultural texts. This trust is obviously due to changes occurring within culture itself. In this paper we suggest that one of the reasons for this transformation is the emergence of interactive texts, hypertext. The emergence of hypertext and the formation of its aesthetics are traced. We demonstrate the influence of hypertext on the formation of the phenomenon of metamodernity.
REALISM IS THE MAIN DRIVING FORCE BEHIND THE SPREAD OF RUSSIAN ART IN NORTHEAST CHINA
Authors:   St. Petersburg State University, Meng Xiangxue
Published: May 2024

This thesis examines the process of dissemination and development of Russian realist art in Northeast China. It analyzes the origins and development of realism in China and the reasons for China's adoption of Russian realist art in certain historical periods.
ANGLO-SAXON ACADEMIC CULTURE AND RUSSIAN SCIENTIFIC COMMUNICATION: "GLOBAL" AND "LOCAL" IN THE REALM OF RUSSIAN SCIENCE
Authors:   Moscow City University, Tivyaeva I.
Published: May 2024

The past decade has been characterized by the endeavors of Russian researchers to integrate into the global academic community, a drive that has received official endorsement. This endorsement is manifested through various channels, including incentives for participation in international events, prerequisites for recipients of grants from the Russian Science Foundation (RNF), criteria for universities involved in the "5-100" and "Priority 2030" programs, as well as the stipulation of having publications in leading international journals and presenting research findings at global academic forums. However, this approach has encountered strong resistance in specific university and research circles, accentuating a dichotomy between "us" and "them." It has led some to compromise scientific ethics by resorting to publications in so-called "predatory" journals and, ultimately, spurred cross-cultural interference within the academic environment, giving rise to novel conference formats and transformations in publishing practices, among other changes. This study places particular emphasis on the impact of Anglo-Saxon academic culture on Russian scientific journals and publication standards, which have undergone substantial modifications to align with international expectations. While changes in the geopolitical landscape during 2022–2023 have prompted a reevaluation of established practices within the academic community, these new external realities do not necessarily signify a complete abandonment by Russian science of the entrenched communicative practices of the preceding decade.
“SEMIOTIC CULTS” AS A PHENOMENON OF MASS CULTURE IN THE DIGITAL AGE
Authors:   St. Petersburg State University, Khokhlova Yu. I. , Sunami A. N. ,   St. Petersburg State University
Published: May 2024

The report examines the phenomenon of so-called "semiotic cults" — communities of like-minded people formed around works of popular culture, both literary and visual (films, cartoons, comics, etc.) and having features of a religious cult. This issue seems to be especially relevant in the context of the digital age, in the context of the widespread use of social networks and the adoption of a paradigm for determining the value of content through "feedback" expressed in likes, comments and the number of subscribers. As an example of such a para-religious movement, the community of "Disney adults" formed around Disney products is cited.
Trade law as foreign relations law
Authors: Wai Robert
Published: May 2024

This article reflects on the normal frame for international trade law in times of resurgent assertions of national interest in domestic politics and in foreign relations. An emphasis on national interest poses special problems when legal and economic relations are fundamentally transnational, necessarily involving multiple and complex connections across national borders and reflecting a diverse and complex pluralism within each national tradition. This is especially true in Canada, which is a society foundationally built on flows of people, goods, capital, and ideas from around the world as well as Indigenous and First Nations societies. A turn to foreign relations law, if made with a critical and transnational perspective, might offer a valuable new frame for trade law in challenging times.
DİJİTAL ORTAMLARDA FEN EĞİTİMİ: DİJİTAL ÖĞRENME PLATFORMLARI ÜZERİNE FEN BİLGİSİ ÖĞRETMEN GÖRÜŞLERİ
Authors: Polat Mehmet , Koç Murat
Published: May 2024

Bu çalışmanın amacı, fen bilgisi öğretmenlerinin perspektiflerinden yola çıkarak, dijital öğrenme platformlarının fen eğitimi üzerindeki etkilerini, kullanım amaçlarını, avantaj ve dezavantajlarını, ve bu platformların derslerde kullanımını engelleyen faktörleri tespit etmektir. Elazığ’ın merkez, ilçe ve köylerinde görev yapan 24 fen bilgisi öğretmeni araştırmanın çalışma grubunu oluşturmuştur. Araştırmada, amaçlı örnekleme yöntemlerinden tipik durum örnekleme yaklaşımı benimsenmiştir. Fenomenoloji deseniyle yürütülen nitel araştırmada, veri toplama aracı olarak yarı yapılandırılmış mülakatlar tercih edilmiştir. Toplanan veriler, tümevarımcı veri analizi metoduyla incelenmiştir. Araştırma bulgularına göre, öğretmenler dijital öğrenme platformlarını genellikle pozitif değerlendirmişler ve bu platformların, soyut kavramları somutlaştırma ve ders içeriğini daha eğlenceli ve ilgi çekici kılma gibi önemli katkılar sağladığını belirtmişlerdir. Ancak, teknik sorunlar, içeriklerin güncellenmesi ve erişimdeki eşitsizlikler gibi zorluklar, platformların etkin kullanımını kısıtlayan unsurlar olarak tanımlanmıştır. Araştırma sonucunda, dijital öğrenme platformlarının eğitimdeki potansiyelini tam olarak gerçekleştirebilmesi için altyapısal iyileştirmeler, içerik güncellemeleri ve öğretmenlerin bu platformları kullanma yetkinliklerinin geliştirilmesi gerektiği vurgulanmaktadır. Nihayetinde, dijital öğrenme platformlarının fen eğitimindeki etkinliğinin artırılabilmesi, bu platformların entegre edilmesi ve eğitimde fırsat eşitliğinin sağlanmasıyla mümkün olabilecektir.
Mediation Effect of Perceived Symptom Change on the Association between COVID-19 Perceptions and Well-Being Controlling for the Effect of Relationship Quality
Authors: Özgülük Üçok S. Burcu , Demirutku Kürşad , Topcu Çiğdem , Chiarolanza Claudia , Randall Ashley K.
Published: May 2024

Most people had a perception of COVID-19 as an illness throughout the COVID-19 pandemic, and this inevitably resulted in developing psychological symptoms which in the end yielded to lower levels of well-being. These experiences affected the people who were in a relationship during the pandemic, hence the quality of their relationship was influenced by all these individual feelings. Regarding this context, the current study aimed to explore the mediation role of perceived symptom change in the association between well-being and COVID-19 perceptions, controlling for the effect of relationship quality. To achieve this goal, 174 (N = 124 women, N = 49 men) participants were recruited. Results of the study put forth that (1) there was a positive association between COVID-19 illness perception and symptom change, (2) there was a negative association between perceived symptom change and well-being, (3) there was a negative association between COVID-19 illness perception and well-being, (4) relationship quality was positively associated with well-being, and (5) the symptom change mediated the association between COVID-19 illness perception and well-being in the case relationship quality was considered as a covariate. Limitations and recommendations for further research are presented.
Attentional Control Scale- Turkish Version: Psychometric Qualities, Factor Structure and its Comparison with Behavioral Measures of Executive Attention
Authors: Altan Atalay Ayşe , Cinli Dilem , Aksungur Umay , Türkakın Esin
Published: May 2024

Attentional control refers to the capacity to voluntarily control attentional resources in a flexible manner. Attentional control was reported to play a fundamental role in self-regulation, emotion regulation, delay of gratification, and psychological distress. The Attentional Control Scale (ACS) was developed to measure perceived attentional control based on shifting and focusing dimensions. The present studies aimed to adapt the Turkish version of ACS and asses its psychometric characteristics. Study 1 aimed to explore the psychometric qualities of the Turkish version with a group of Turkish individuals (N = 428, 306 women) between the ages of 18 and 68 and supported the two-factor model of ACS consisting of 17 items in total. The results supported that shifting, focusing, and total ACS showed adequate internal consistency, test-retest reliability, and convergent validity evidence based on its significant correlations with measures of anxiety, depression, and repetitive negative thinking, signifying its proper psychometric characteristics. In Study 2 (N = 97, 65 women), the association of ACS with behavioral attentional control measures was examined, and non-significant associations between self-report and behavioral measures of attentional control were denoted. These findings signified that rather than indicating the individual’s actual attentional control capacity, ACS assessed how the individual perceives their own attention control capacities. Taken together, the results suggest that the Turkish form of ACS is a valid and reliable scale that can be used to assess perceived attentional control capacity based on shifting and focusing domains, particularly in the research setting.
Educational and academic text as a means of developing the cognitive and
communicative potential of the future bilingual teacher of the Russian language
Authors: Medvedeva N. V.
Published: May 2024

The current concept in this article is the idea that we should take into account
the psycholinguistic features of a bilingual personality of a natural foreign-Russian
bilingual when working with an educational and academic text in the process of preparing
a future bilingual teacher of the Russian language. Two thesauri: Concepts/notions/
images/ideas of native and Russian linguistics represent (T1) and (T2) which overlap
in educational and theoretical pictures of the world of ethno-lingual consciousness
of a bilingual personality. In this regard, teaching theoretical concepts requires the
“alignment” of the existing stereotypical apprehensions, stereotypical reasonings fixed in
the mind of a bilingual towards mastering theoretical concepts of the Russian language.
The purpose of the article is to show the possibilities of working with educational
and academic texts in a bilingual audience, which allows developing the cognitive
and communicative potential of future teachers of the Russian language on the basis
of textual and interpretive activities with educational and theoretical text. Sections of
the article include 1) theoretical information about the specifics of the ethno-lingual
consciousness of a bilingual personality of a Komi-Permyak student in the field of ideas
about the theoretical concepts of Russian linguistics, 2) criteria for selecting educational
and academic texts for the development of the cognitive and communicative potential of
a future bilingual teacher of the Russian language, 3) teaching interpretive activity based
on working with educational and academic text in linguistic and methodological aspects
when working with bilingual students.
Strategies for developing a teacher’s soft skills: problems and prospects of research
Authors: Chertov V. F. , Erokhina E. I. , Getmanskaya E. V.
Published: May 2024

The soft skills of a teacher are considered in the article from the perspective of pedagogical comparative studies, which reveal the general and specific in historical phenomena. The latest domestic and foreign publications in which a working typology of soft skills is constructed were the subject of the thematic analysis. The necessity of developing soft skills of a teacher already at the stage of professional education is argued. The spread in practice of a uniform approach to the development of soft skills of teachers, implemented disregarding the age, experience and personal qualities of the teacher, has been noted. A typological connection has been established between the term “soft skills” and similar concepts traditionally used in domestic pedagogy. Four groups of soft skills are adopted as a working typology: communication, collaboration, critical thinking, creativity. At the same time, self-presentation and media competence were added for mixed-age groups of teachers. A teacher’s long-term task in developing students’ soft skills is formulated based on the teacher’s own experience of using soft skills in their professional activities.
Using VR art apps in contemporary art
Authors: Guangsheng Ma
Published: May 2024

The relevance of the study is due to the need to integrate modern computer
technologies into the environment of contemporary art. Given the current changes in
the world and specifically in the field of virtual technologies, it must be said that the
problem of studying the possibilities of these technologies in various fields is becoming
extremely relevant. Virtual technologies are introduced today in the economy, law,
technology, as well as in the field of art, which is of the greatest interest to us. Virtual
reality today has become not only a means of entertainment, but also a way that allows
artists to create – due to various programs and applications, such a phenomenon as VR
drawing has arisen. Evaluating the various means that this phenomenon has introduced
into the field of creativity today, the question arises: how convenient and useful are the
tools with which virtual masterpieces are created today and how they can be used in
the educational process.
The role of critical thinking as a factor of the development
of the value-sense sphere of schoolchildren
Authors: Stulev D. I.
Published: May 2024

This article analyzes the concept of «value-sense sphere of a personality»,
considers the factors of development of value-sense sphere of students in modern school, in
particular, the role of such a personal resource as critical thinking of modern schoolchildren
in the context of formation and development of their value-sense sphere of personality. The
article analyzes the influence of the level of development of critical thinking of students on
their ability to formulate and justify their own spiritual values and personal meanings, as well
as on the ability for deep reasoning around them. The list of properties inherent in a person
possessing critical thinking and their connection with his/her system of value orientations
and system of personal meanings in the context of formation and development of value-sense
sphere of schoolchildren in a modern school is given.
Students' Problem-Solving Ability Using Picture Story Contexts
Authors: Lisnani  , Inharjanto Anselmus
Published: May 2024

Kemampuan pemecahan masalah matematis menjadi salah satu komponen yang perlu dianalisis untuk mengetahui kemampuan peserta didik terhadap satu topik pembelajaran. Penelitian ini bertujuan untuk menganalisis kemampuan pemecahan masalah matematis peserta didik pada materi bangun datar, pengukuran panjang dan berat. Metode penelitian yang digunakan adalah kualitatif deskriptif. Instrumen pengumpulan data melalui tes, kuesioner, dan dokumentasi. Keseluruhan data tersebut dianalisis dan dideskrispsikan oleh peneliti. Subjek dalam penelitian ini adalah peserta didik kelas IV di salah satu sekolah swasta di Palembang berjumlah 14 orang yang diperoleh melalui purposive sampling. Hasil dari penelitian ini adalah kemampuan pemecahan masalah pada materi bangun datar dan pengukuran pada peserta didik kelas IV di salah satu sekolah swasta tersebut sebesar 75,59% yang artinya berkategori baik. Kemampuan pemecahan masalah peserta didik kelas IV perlu ditingkatkan terutama pada sesuatu yang sifatnya konkret dengan membiasakan peserta didik memberikan soal-soal berkonteks cerita yang mengarah ke AKM, PISA, dan HOTS kedepannya.
 
Mathematical problem-solving ability is one of the necessary components to analyze as it demonstrates students' ability to comprehend a learning topic. This study aimed to analyze students' mathematical problem-solving skills on flat shapes, measuring length and weight. This descriptive qualitative study used tests, questionnaires, and document analysis to collect the data. All of the data were analyzed and described by the researcher. The participants of the study were 14 fourth grade students in a private school in Palembang selected through purposive sampling technique. The study revealed that the students’ problem-solving abilities on flat shapes and measurements scored 75.59%, which was categorized as “good”. The problem-solving abilities of fourth graders need to be improved, especially on concrete objects by inuring students to story-context questions that promote AKM, PISA, and HOTS in the future.
Description of Hemoglobin Levels in Prospective Donors Over 46 Years Old at UDD PMI Jepara Regency
Authors: Luthfia Alya , Wikandari Ririh Jatmi , Widodo Widodo
Published: May 2024

Blood donation is the process of taking part of blood from the body of a healthy person and given to people who need blood voluntarily (Ibrahim et al., 2021). Hemoglobin level examination is one of the donor selection checks to find out whether someone is successful or not to donate blood. A person can donate blood if the hemoglobin level shows a result of 12.5 g / dL-17 g / dL. The factor causing the rejection of most blood donations in Indonesia is due to low hemoglobin levels (Putri Afrianti, 2022). The case of high Hb levels is also one of the factors that causes rejection in donor selection (Nuraini Kwarta, 2021). The levels and activity of substances in the blood can be affected by age. Neonates have higher Hb levels than adults due to loss of active tissue mass and many people whose function has been reduced, resulting in reduced Hb levels (Paramahita et al., 2020). The purpose of this study was to measure hemoglobin levels in prospective donors aged more than 46 years at UDD PMI Jepara Regency. This type of research uses a quantitative approach with a cross-sectional descriptive study research model taken from the SIMDONDAR database. Based on the results of the study, it was found that the majority of prospective donors showed normal hemoglobin levels as many as 480 prospective donors (94.86%), and more prospective donors who had blood type O (+) as many as 187 prospective donors (36.96%), most prospective donors were male as many as 342 prospective donors (67.59%), and the majority of prospective donors were declared to have passed the donor selection as many as 480 prospective donors (94.86%).
Life of Indigenous Communities During the COVID-19 Pandemic
Authors: Umanailo Muhamad Chairul Basrun , Umanailo Annisa Retrofilia , Umanailo Askar Daffa Sophia
Published: May 2024

The existence of indigenous peoples is often forgotten in development planning. Their position and existence are even threatened by the development itself, especially the work of those who have natural resources or other potential, so that not a few indigenous peoples then have to confront the government. The condition of Buru Regency, where there are still many indigenous communities, in its development is enough to provide space for them to continue to exist and develop themselves in socio-economic life. However, in reality, not everything that has been done can cover the existing communities, so some of them still have to survive under specific conditions. This study seeks to identify their empowerment in daily life during the Covid-19 pandemic. The approach used in this study is qualitative. The number of informants to be interviewed is 45, taken purposively, considering that the respondents are considered parties involved in achieving the research objectives. The findings show that the COVID-19 pandemic has changed indigenous people whose lives are closely related to tradition and who face difficult times fulfilling their livelihoods. Their habits have not fully become a means of fulfilling the necessities of life. Their economic condition, which is very dependent on nature, becomes even more complicated when the government implements various restrictions to control the spread of the virus. There should be a government effort to rehabilitate production patterns in contact with technology. This action is intended to reduce dependence on nature and has more proportional gender relations so that the fulfillment of life has better potential for sustainability.
Experimental Study on Compressive Strength of Concrete Under Simple Curing and Encased in Steel Mould
Authors: Dai Xianghe
Published: May 2024

This paper presents a comparison and analysis of compressive strength development of normal concrete under three typical simple curing methods: air curing, water immersion curing, plastic film cover curing, and maintained in steel mould. Portland cement with 30% fly ash was used, concrete cubic compressive strength at 28 days and 60 days were tested.  The comparison of experimental results shows that concrete samples applied 7-day water immersion curing and samples maintained in steel moulds up to testing date displayed excellent compressive strength development compared with concrete samples under air curing. This implies core concrete in steel tubular members might develop a higher strength than design assumption based on standard curing procedure. Wrapping concrete with plastic film for more than 7 days as a curing method might delay the concrete strength development in early stage. Water immersion curing for long period may not accelerate concrete compressive strength gain.
Development of a Green Procurement Method for Eutrophic and Anoxic Coastal Areas
Authors: Xiarchis Haris , Stephanedes Yorgos J. , Saranti Panagiota-Georgia I. , Marousi Konstantina , Panayiotou Charalambos
Published: May 2024

Understanding the intertwined common challenges of the sea-land chain by treating the pollution problems of eutrophic and anoxic coastal ecosystems resulting from land-based and other pollution sources, is essential for the green procurement of products and services in wastewater management. The research activities took place under the aegis of project, “Blue-Greenway,” and field results were obtained in Greece, Romania and Cyprus. The most efficient method to address these challenges is via a dual approach, (a) short-term restoration measures in the sea part of the chain, and (b) land measures for identifying green products & services in wastewater management. According to the baseline best practices in the field describing the linked agriculture-eutrophication issue, everyday farming activities such as tilling, use of pesticides and fertilizers can give rise to contamination of soil and water supplies. Toxic pollutants from land-based sources are found in fresh and marine waters, ranging from agricultural nutrients, such as organic compounds, to pharmaceuticals. The main output of the present research was to design, build and operate a unified platform, hosting all the necessary tools for an efficient, sustainable electronic procurement method, aiming to bring together public-private operators who are active in the field of green public procurement. The unified platform has been used by relevant target groups to provide innovative solutions for improving the environmental status of eutrophic and anoxic coastal ecosystems based on the identification of general specifications & standards to govern green eProcurement models and green criteria, leading to the development of an integrated procurement model.
How does organizational commitment in employees relate to work engagement in millennial employees in the era of the Fourth Industrial Revolution?
Authors: Jakayati Novia , Prahara Sowanya Ardi
Published: May 2024

The era of the Industrial Revolution 4.0 requires the world to continue to develop. This affects the performance of human resources at this time. Therefore, employees who are competent in their fields are needed. One of them is millennial generation employees who are known to be able to adapt and control technology. However, millennial employees have characteristics that make them quickly bored, so they easily decide to leave their jobs. This is undoubtedly related to the engagement of employees of the millennial generation. Therefore, millennial generation employees need organizational commitment; by committing, they can increase their sense of attachment to the company. The subjects in this study amounted to 60 millennial-generation employees with the characteristics of working for at least one year and aged between 21 and 41 years. The data collection method in this study used the Work Engagement Scale and the Organizational Commitment Scale. The data analysis technique used is product-moment correlation from Karl Pearson. The results of data analysis were obtained with the correlation coefficient value, which means there is a significant positive relationship between Organizational Commitment and Work Engagement.
The impact of loneliness and anonymity on self-disclosure among social media X users
Authors: Maindah NurLaili Asari  , Tatik Mukhoyyaroh
Published: May 2024

The rapid development of social media enables individuals to self-disclose on communication sites within social media. This study examines the influence of loneliness and anonymity on self-disclosure among users X (Twitter). The subjects of this research are X users with anonymous accounts ranging from 17 to 40 years old, totaling 356 participants. Employing a quantitative approach, the researcher adopted the Revised Self-Disclosure Scale (RSDS) to measure the self-disclosure variable, the UCLA Loneliness version 3 to measure loneliness, and the Lee, Choi, and Kim anonymity scale to measure anonymity. The research results indicate that both loneliness and anonymity, both partially and simultaneously, impact the self-disclosure of social media X users.
ФОРМУВАННЯ ЗЕЛЕНИХ НАВИЧОК У ЗДОБУВАЧІВ ПРОФЕСІЙНИХ КВАЛІФІКАЦІЙ
Authors: Шамралюк Олена , Пархомюк Любов
Published: May 2024

The problem of developing green skills among workers in various sectors of the economy has been updated. The role of vocational education institutions in the ecological transformation of the economy and society is revealed. The practical experience of forming green skills among those acquiring professional qualifications through the implementation of eco-oriented projects "Solar energy as a component of the educational process", "Solar benches", "Public air quality monitoring of the city of Khmelnytskyi" is presented.
Penguatan Keterampilan Pengelolaan Wihara bagi Pengurus Wihara-Wihara di Kabupaten Lampung Timur
Authors: Kunarso Kunarso , Subekti Puja , Sapardi Sapardi , Putra Edi Ramawijaya , Heriyanto Heriyanto , Suwarni Iin , Dharma Andhika Mustika , Widiyono Eling
Published: May 2024

ABSTRAK Keterampilan pengelolaan wihara merupakan hal yang perlu terus dilakukan bagi pengurus ataupun calon pengurus. Hal ini dikarenakan pengurus merupakan garda terdepan dalam menciptakan eksistensi sebuah organisasi. Selain itu wihara sebagai tempat ibadah juga dituntut untuk terus berkembang guna membantu masyarakat tidak hanya dalam bidang agama namun juga dibidang-bidang lainnya seperti ekonomi, sosial, ataupun kesehatan. Kegiatan Pengabdian kepada Masyarakat ini bertujuan untuk meningkatkan pemahaman terkait keterampilan pengelolaan wihara yang diharapkan akan menunjang tercapainya visi, misi, serta tujuan organisasi. Kegiatan ini dilakukan dengan menggunakan metode penyuluhan yang terbagi menjadi beberapa tahap yakni persiapan, pelaksanaan, dan evaluasi. Kegiatan ini dilaksanakan di Wihara Buddha Dipa dengan peserta berjumlah 30 orang yang merupakan pengurus wihara di Kabupaten Lampung Timur. Hasil kegiatan menunjukkan bahwa peserta mengalami peningkatan pemahaman berkaitan dengan pemahaman sebesar 87,5%. Secara keseluruhan kegiatan berlangsung dengan lancar meskipun terdapat beberapa kendala yang bersumber dari aspek internal ataupun eksternal akan tetapi dapat teratasi dengan baik. Kata Kunci: Keterampilan, Manajemen, Pengelolaan, Wihara  ABSTRACT Temple management skills are something that needs to be done continuously for administrators or prospective administrators. This is because the board is the front line in creating the existence of an organization. In addition, the temple as a place of worship is also required to continue to grow to help the community not only in the field of religion but also in other fields such as economic, social, or health. This Community Service activity aims to increase understanding of temple management skills that are expected to support the achievement of the organization's vision, mission, and goals. This activity is carried out using counseling methods which are divided into several stages, namely preparation, implementation, and evaluation. This activity was carried out at Dipa Temple with 30 participants who were temple administrators in East Lampung Regency. The results of the activity showed that participants experienced an increase in understanding related to understanding by 87.5%. Overall, the activity ran smoothly even though there were several obstacles originating from internal or external aspects, but it could be overcome properly. Keywords: Skills, Management, Management, Temple
Kombinasi Digital Marketing, Marketing Konvensional Dalam Strategi Pemasaran Produk UMKM Di Kampung Cikandang
Authors: Rahayu Wati , Novianti Linda , Istiqomah Yuliani
Published: May 2024

Digital Marketing is product marketing through digital media, while conventional marketing uses traditional media such as print, television and radio. The majority of MSMEs in Cikandang Village choose to use these two promotional systems, especially for culinary products because they are considered more effective. This research was carried out using documentation data collection techniques with MSMEs in Kp. Cikandang Rw. 06 Etc. Cileunyi Kulon. The research results show that combining digital marketing and conventional marketing in product marketing strategies is effective in reaching a wider market. This combination has proven to be very effective for marketing products sustainably. MSME players can expand their marketing reach by combining two marketing systems, namely using various digital media such as Go Food, Grab Food, Shopee Food, Whatsapp and other platforms provided by business owners as part of marketing, and at the same time business owners can promote their products. with a direct marketing system (conventionally) with the aim of achieving a wider market share
Mucosal-associated invariant T cells are functionally impaired in pediatric and young adult patients following allogeneic hematopoietic stem cell transplantation and their recovery correlates with clinical outcomes
Authors: Galaverna Federica , Flamini Sara , De Luca Carmen Dolores , Pili Ilaria , Boccieri Emilia , Benini Francesca , Quagliarella Francesco , Rosignoli Chiara , Rosichini Marco , Genah Shirley , Catanoso Marialuigia , Cardinale Antonella , Volpe Gabriele , Coccetti Marianna , Pitisci Angela , Li Pira Giuseppina , Carta Roberto , Lucarelli Barbarella , Del Bufalo Francesca , Bertaina Valentina , Becilli Marco , Pagliara Daria , Algeri Mattia , Merli Pietro , Locatelli Franco , Velardi Enrico
Published: May 2024

Mucosal-associated invariant T (MAIT) cells are innate-like T cells implicated in the response to fungal and bacterial infections. Their contribution to restoring T-cell immunity and influencing hematopoietic stem cell transplant (HSCT) outcomes remains poorly understood. We retrospectively studied MAIT-cell recovery in 145 consecutive children and young adults with hematologic malignancies undergoing allogeneic (allo)-HSCT between April 2019 and May 2022, from unrelated matched donor (MUD, N=52), with standard graft-versus-host-disease (GvHD) prophylaxis, or HLA-haploidentical (Haplo, N=93) donor after in vitro αβT/CD19-cell depletion, without post-HSCT pharmacological prophylaxis. With a median follow-up of 33 months (range, 12-49 months), overall survival (OS), disease-free survival (DFS), and non-relapse mortality (NRM) were 79.5%, 72%, and 7%, respectively; GvHD-free relapse-free survival (GRFS) was 63%, while cumulative incidence of relapse was 23%. While αβT cells were reconstituted 1-2 years post HSCT, MAIT cells showed delayed recovery and prolonged functional impairment, characterized by expression of activation (CD25, CD38), exhaustion (PD1, TIM3) and senescence (CD57) markers, and suboptimal ex vivo response. OS, DFS, and NRM were not affected by MAIT cells. Interestingly, higher MAIT cells at day +30 correlated with higher incidence of grade II-IV acute GvHD (19% vs. 7%, P=0.06). Furthermore, a greater MAIT-cell count tended to be associated with a higher incidence of chronic GvHD (cGvHD) (17% vs. 6%, P=0.07) resulting in lower GRFS (55% vs. 73%, P=0.05). Higher MAIT cells also correlated with greater cytomegalovirus (CMV) reactivation and lower late blood stream infections (BSI) (44% vs. 24%, P=0.02 and 9% vs. 18%, P=0.08, respectively). Future studies are needed to confirm the impact of early MAIT-cell recovery on cGvHD, CMV reactivation, and late BSI.
Single-cell CRISPR screening characterizes transcriptional deregulation in T-cell acute lymphoblastic leukemia
Authors: Meyers Sarah , Gielen Olga , Cools Jan , Demeyer Sofie
Published: May 2024

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia caused by accumulation of multiple genetic alterations in T-cell progenitors. However, for many genes it remains unknown how their mutations contribute to disease development. We therefore performed two single-cell CRISPR screens in primary pro-T cells ex vivo to study the transcriptional impact of loss-of-function alterations in T-ALL and correlate this with effects on cell fitness. The various perturbations were clustered based on their effects on E2F/MYC or STAT/NOTCH signatures, which play a defining role in driving T-cell proliferation. Many of the perturbations resulted in positive effects on the STAT and NOTCH signatures and were predicted to behave as haploinsufficient tumor suppressors in T-ALL. Additionally, Spi1 was identified as an essential gene for pro-T-cell survival, associated with deregulation of the MYC signature and epigenetic consequences. In contrast, Bcl11b was identified as a strong tumor suppressor gene in immature T lymphocytes, associated with deregulation of NF-kB and JAK/STAT signaling. We found a correlation between BCL11B expression level and JAK/STAT pathway mutations in T-ALL patients and demonstrated oncogenic cooperation between Bcl11b inactivation and JAK3 hyperactivation in pro-T cells. Altogether, these single-cell CRISPR screens in pro-T cells provide fundamental insights into the mechanisms of transcriptional deregulation caused by genetic alterations in T-ALL.
Revised evaluation objectives of the Korean Dentist Clinical Skill Test: a survey study and focus group interviews
Authors: Kim Jae-Hoon , Kim Young J , Ma Deuk-Sang , Park Se-Hee , Pae Ahran , Shim June-Sung , Yang Il-Hyung , Jung Ui-Won , Choi Byung-Joon , Chun Yang-Hyun
Published: May 2024

Purpose: This study aimed to propose a revision of the evaluation objectives of the Korean Dentist Clinical Skill Test by analyzing the opinions of those involved in the examination after a review of those objectives.Methods: The clinical skill test objectives were reviewed based on the national-level dental practitioner competencies, dental school educational competencies, and the third dental practitioner job analysis. Current and former examinees were surveyed about their perceptions of the evaluation objectives. The validity of 22 evaluation objectives and overlapping perceptions based on area of specialty were surveyed on a 5-point Likert scale by professors who participated in the clinical skill test and dental school faculty members. Additionally, focus group interviews were conducted with experts on the examination.Results: It was necessary to consider including competency assessments for “emergency rescue skills” and “planning and performing prosthetic treatment.” There were no significant differences between current and former examinees in their perceptions of the clinical skill test’s objectives. The professors who participated in the examination and dental school faculty members recognized that most of the objectives were valid. However, some responses stated that “oromaxillofacial cranial nerve examination,” “temporomandibular disorder palpation test,” and “space management for primary and mixed dentition” were unfeasible evaluation objectives and overlapped with dental specialty areas.Conclusion: When revising the Korean Dentist Clinical Skill Test’s objectives, it is advisable to consider incorporating competency assessments related to “emergency rescue skills” and “planning and performing prosthetic treatment.”
PUBLIC MANAGEMENT OF THE DEVELOPMENT OF THE HIGHER EDUCATION SYSTEM IN UKRAINE
Authors: KRYSHTANOVYCH SVITLANA , GAVRYSH IRYNA , TAMOZHSKA IRYNA , TROBIUK VOLODYMYR , HRODZ NATALIIA , KHLTOBINA OLEKSANDRA
Published: May 2024

The article considers core challenges and problems of public management of Ukrainian higher education system within the global landscape of higher education development. Systemic analysis of factors influencing higher education system in Ukraine is carried out based on complex vision, including social and political factors. Overall trends and practices observed in higher education of different countries is carried out, with outlining of the state-of-the art and prospects of Ukrainian higher education on the background of this landscape. Penta helix model is mentioned as one of potentially effective directions to be included in public management of Ukrainian higher education system development.
DECOMPOSITION OF INFORMATION PROVISION OF THE SYSTEM OF PUBLIC MANAGEMENT OF INVESTMENT RISKS IN THE DEVELOPMENT OF HUMAN CAPITAL
Authors: IZHA MYKOLA , PAKHOMOVA TETYANA , BRYCH LESIA , MATVIEIENKO IRYNA , YEVSTIUNINA YULIIA
Published: May 2024

The article emphasizes that investing into human capital is crucial for any nation hoping to achieve long-term economic growth, it contributes to the development of a trained labor force that can promote innovation and technological advancement, increase productivity, and adjust to shifting economic situations. It is shown that the study of issues related to the accumulation of high-quality human capital is of particular relevance. There is an urgent need to study various aspects of investing in human capital at all stages of its reproduction in order to develop scientifically based recommendations for preserving already accumulated human capital and determining the possibilities for the effective distribution of investments in the development of human capital. Based on two crucial components of human resource development – education and healthcare – provisions of state management of investment risks in this capital development are outlined and decomposition model is suggested.
THE IMPACT OF DISTANCE EDUCATION ON THE MENTAL HEALTH OF APPLICANTS FOR EDUCATION: THE ROLE OF DIGITAL PSYCHOLOGICAL SUPPORT
Authors: NOSKOVA MARGARYTA , SVISTELNYK IRYNA , KOVTUN IRYNA , ZHYGLO OKSANA , VENHRIN MARTA
Published: May 2024

Poor mental health among university students remains a pressing public health issue. The conditions of distance learning causes even more challenges for students’ mental health and wellbeing. Over the past few years, digital health interventions have been developed and considered promising in increasing psychological wellbeing among university students. The study attempts to systematize and analyze the existent experience of creating digital psychological support services for university students, including virtual clinics, peer platforms, etc. It is concluded that combining peer engagement and involvement of students in platforms development is the optimal and highly necessary element to be added to the landscape of digital psychological support services for students in distance education.
PARTNERSHIP INTERACTION OF THE STATE AND CIVIL SOCIETY AS A MECHANISM FOR THE IMPLEMENTATION OF UKRAINE'S HUMANITARIAN POLICY IN THE CONDITIONS OF EUROPEAN INTEGRATION
Authors: OPANASHCHUK PETRO , IEMELIANOV VOLODYMYR , KRASNYK VADYM , LOPUSHYNSKYI IVAN , TESLENKO PAVLO , TOTSKA VITALIIA
Published: May 2024

The article represents an attempt to analyze the landscape of partnership between government and civil society within the implementation of humanitarian policy in Ukraine and EU. Theoretical provisions of such partnerships are presented, and real state-of-the art in humanitarian space of the USA, EU, and Ukraine is investigated. Particularly, the phenomenon of precariat is considered through the lens of its role for civil society’ stability and designing effective humanitarian policies to improve social capital.
DIGITAL TRANSFORMATION OF THE CONSTRUCTION OF PARTNERSHIP INTERACTION OF THE STATE AND THE IMPLEMENTATION OF HUMANITARIAN POLICY OF UKRAINE IN THE LANDSCAPE OF EUROPEAN INTEGRATION AND INTERNATIONAL ECONOMIC RELATIONS
Authors: HORNYK VOLODYMYR , SIMAK SERGII , YEVMIESHKINA OLENA , PUTINTSEV ANATOLII , PASICHNYI ROMAN , YURKIVSKYI OLEKSANDR
Published: May 2024

The article makes an attempt to comprehend the place and role of humanitarian policy in today globalization landscape, in particular within the framework of economic diplomacy. The experience of EU in designing approaches to construction of state partnerships in development of social capital as the core of humanitarian policy is analyzed and prospects for Ukraine are outlined. The role of digital means (ICT) in humanitarian policy is considered, based on penta-helix paradigm.
SOSIALISASI PENGGUNAAN APLIKASI YOUTUBE YANG EFEKTIF SEBAGAI SUMBER BELAJAR DAN MEDIA PEMBELAJARAN BAHASA INGGRIS
Authors: Sabila Dara
Published: May 2024

Perkembangan teknologi saat ini berpengaruh sangat besar pada beberapa aspek kehidupan termasuk pendidikan. Terdapat beberapa media platform yang dapat digunakan sebagai media dan sumber belajar salah satunya yaitu aplikasi YouTube. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan sosialisasi terkait bagaimana cara menggunakan YouTube sebagai media dan sumber belajar yang efektif kepada peserta didik pada jenjang kelas X. Mitra dalam kegiatan pengabdian ini yaitu Sekolah Alam Cikeas Bogor pada jenjang Sekolah Menengah Atas (SMA), dimana permasalahan yang ditemukan yaitu rendahnya pengetahuan peserta didik khusus nya pada jenjang kelas X untuk menggunakan YouTube sebagai media dan sumber belajar yang tepat dalam proses belajar Bahasa Inggris. Terdapat 30 peserta didik yang ikut serta dalam kegiatan pengabdian. Sebelum melakukan sosialisasi, peserta diberikan kuesioner dan hasilnya menunjukan bahwa terdapat 33% peserta didik tertarik akan media YouTube sebagai media dan sumber belajar. Kemudian, hasil kuesioner juga menunjukan bahwa terdapat dua cara peserta didik menggunakan YouTube; (1). YouTube memfasilitasi ceramah atau kuliah yang berisikan penjelasan materi. (2). video- video berbahasa inggris yang lain seperti wawancara, diskusi, monolog yang bisa digunakan sumber data variasi bahasa khususnya Bahasa Inggris. Adapun cara menggunakan YouTube yang efektif yaitu (1). Pilihlah beberapa video YouTube yang sesuai dengan tujuan pembelajaran Bahasa Inggris yang ingin di capai, (2). (3). Memfasilitasi peserta didik untuk mereview materi pada video YouTube.
Regenerasi Organisasi Siswa Intra Sekolah (OSIS) Dalam membentuk Kepemimpinan Siswa di SMK Al- Gina Paku Haji Kabupaten Tangerang
Authors: Setyawati Ariesta , Nurislamiah Siti , Utami Wanda Yulia , Fahmi Rizal , Pratama Aditya , Hasim Hasim , Rosbandi Rosbandi
Published: May 2024

Pemilih pemula adalah mereka yang telah berusia 17-21 tahun, mayoritas pemilih pemula adalah pelajar (SMA), mahasiswa dan pekerja muda yang telah memiliki hak suara dan tercantum dalam daftar pemilih tetap (DPT). Pembelajaran demokrasi salah satunya adalah regenerasi OSIS melalui pemilihan ketua serta peralihan kepengurusan. Bagi yang sudah terpilih sebagai pemimpin akan menjalankan tugas dan melanjutkan program program OSIS periode lama yang belum tuntas dan menjalankan program program baru sesuai dengan ide dan gagasan untuk meningkatkan kegiatan yang positif di lingkungan SMK AL GINA. Tujuan Penulisan adalah menganalisa proses pemilihan ketua OSIS yang ada di SMK Al Gina. Sistem yang berjalan dalam proses pemilihan ketua OSIS dilakukan secara manual yaitu dengan panitia mengadakan pencoblosan dan mengambil hasil pemungutan suara terbanyak. Metodologi Analisa menggunakan Pengumpulan Data dan menganalisa secara teoritis Sistem Pemilihan Ketua OSIS secara umum dan yang sedang berjalan. Kemudian melakukan wawancara dengan pihak sekolah yang bersangkutan untuk mengetahui permasalahan yang dihadapi serta untuk mengetahui proses pada sistem pemilihan ketua OSIS yang sedang berjalan dengan metode Analisa. Hasil yang dicapai yaitu menerapkan sistem pemilihan ketua OSIS pada SMK Al Gina yang selama ini masih cara manual.