bluuebunny/crossref_metadata_2025 huggingface dataset:
Avaliação no ensino superior: uma análise da prática
Authors: Luz Samoara Viacelli da , Moreira Herivelto
Published: November 2022

O objetivo deste artigo é analisar como acontece a avaliação de desempenho dos acadêmicos nos cursos de graduação em Engenharia Civil, de Computação, Elétrica, Eletrônica e Mecânica em três campi de uma universidade pública do sul do Brasil. A metodologia de pesquisa utilizada foi o delineamento misto sequencial explanatório. Os principais resultados mostram que os professores diversificam as estratégias de avaliação utilizadas, mas, apesar disso, o processo de avaliação é centrado no professor e não corresponde a conhecimentos pautados em discussões atuais da área da didática do ensino superior e de ensino de engenharia, como a avaliação formativa.
Redes económicas jesuíticas en el momento de su expulsión (1767): El caso del Colegio Máximo y la Provincia de Santafé
Authors: Galindo-Zuluaga Julián
Published: November 2022

En este artículo se analizan aspectos de la vida económica de la Compañía de Jesús al momento de su expulsión de la provincia de Santafé (Bogotá). Se estudian características del mercado interno jesuita, las relaciones entre el circuito hacienda-colegio, el funcionamiento y especialización de sus haciendas de ganado, y las tácticas que manejaban frente al mercado de la carne. Como objetivo se busca analizar algunas estrategias efectuadas por los jesuitas, quienes permitieron el desarrollo de la red económica en la Provincia de Santafé, activas al momento de su expulsión, en 1767. Para ello, se contrastan diferentes fuentes primarias de archivo que exponen cifras sobre la vida económica de los ignacianos. Se concluye con varios elementos que replantean la magnitud de los jesuitas neogranadinos y la mayor incidencia que tuvieron en la esfera ganadera y agrícola del virreinato.
INTEGRAL POTENTIAL EQUATION FOR STURM-LIOUVILLE OPERATOR WITH DELAY
Authors:   University of Zenica, Kalčo Ismet , Nedić Dragana ,   University of East Sarajevo
Published: November 2022

In this paper, we deal with the construction of an integral equation by potential for the Sturm-Liouville operator with a delay for the case when We solved the integral equation by the step method, constructed the characteristic functions and solved the inverse problem for the given conditions.
NOTE ON AN ALGORITHM THAT HIDES AN OTHER ALGORITHM
Authors:   University F. ABBAS, Daili Noureddine
Published: November 2022

In this paper, we study and prove some results on an algorithm that hides an other algorithm. We present the main algorithms used in this work and the associated convergence results.
Successful reintroduction of landrace orange maize in rural Malawi is not related to the nutritional knowledge of women in farming families
Authors:   University of Malawi, Katola AA , Katundu MC , Ndolo VC , Tembo DT , Stark AH ,   The Hebrew University of Jerusalem
Published: November 2022

Vitamin A deficiency is a global health challenge, particularly in the developing world. Diet based approaches, using locally available foods, are recommended for providing long term, sustainable solutions. The ProFarmer project, initiated in Malawi, encouraged local farmers to re-adopt landrace crop varieties. Orange maize was used as a case study. Over time, reintroducing this carotenoid-rich crop is predicted to increase provitamin A content in the Malawian diet. Furthermore, it is considered a relatively simple, cost-effective approach that has the potential to reduce dependence on food fortification. This study was aimed at evaluating the impact of the reintroduction of landrace orange maize on nutrition knowledge, attitudes and behaviours (KAB) in women of farming families that currently cultivate the crop. Women were selected, as they are largely responsible for food preparation and providing healthy foods for their families. Additionally, the overall diet adequacy in women living in rural Malawi was assessed. A total of 336 females took part in the cross-sectional study. Before the study, the participating farming families underwent a training program run by local Agriculture Extension workers prior to receiving seeds for cultivation. The training included an explanation of the rationale behind reintroducing landrace maize and nutrition education regarding the health aspects of providing provitamin A through locally grown foods. Families that had recently joined the project and families that had already harvested the crop in previous years were included in the study sample. A semi-structured questionnaire was used to determine KAB regarding orange maize. Diet quality was also assessed using the FAO Minimum Dietary Diversity questionnaire (MDD-W) designed for women. Independent t-tests and Chi-square tests were performed where appropriate. Positive attitudes towards growing and consuming landrace orange maize were recorded. However, only 32% of the women understood the nutritional benefits. Dietary Diversity scores, a proxy for nutrient adequacy, were low with only 34% of women consuming a sufficiently diverse diet. Despite low levels of nutritional knowledge, landrace orange maize was well accepted by families in rural Malawi and presents an affordable, sustainable option for increasing dietary sources of provitamin A. Nutrition education emphasizing the advantages of eating orange maize and expanding diet diversity is recommended in Malawi. Key words: landrace orange maize, Vitamin A, nutrition knowledge, Malawi, carotenoids, diet diversity, women, sustainability
Transcriptome Analysis of the Regulation of Retinoic Acid on the Growth and Development of Brandt’s Vole
Authors: Batdorj L. , Xu C.M. , Li S. , Deng Y. , Babar H.C. , Tu X.B. , Zhang Z.H.
Published: November 2022

Background: Studying the growth and developmental mechanisms of steppe (Brandt’s) voles is important for biological control and protection of steppe ecology. In this paper, preliminary biological experiments’ data showed that the mortality of Brandt’s vole increased after retinoic acid treatment. Methods: LPH inhibitor, retinoic acid, quercetin and DMSO (Standard treatment concentration 10 mg/ml) were given them through oral with the help of Animal oral gavage feeding needles. The hind legs muscles of surviving Brandt’s voles were collected for transcriptomic analysis. Result: A total of 4047 and 2251 up- and down-regulated transcripts, respectively, were observed upon retinoic acid treatment compared to the DMSO (control) treatment. Transcriptomic changes were enriched significantly in 31 KEGG pathways, most of which were involved in sugar metabolism, particularly for fructose and mannose (ko00051), protein digestion and absorption (ko04974), phenylalanine metabolism (ko00360), tyrosine metabolism (ko00350) and the PI3K-Akt signaling pathway (ko04151), which is related to growth and development. A total of 114 differentially expressed genes were screened as candidate genes according to the enrichment results, including c-Jun N-terminal kinase and tubulin epsilon chain verified by RT-PCR. Ultimately, we proposed a preliminary regulatory molecular mechanism of retinoic acid relevant to mouse development and death.
“Ese apellido social me da ¡una responsabilidad!” Aproximaciones al perfil de emprendedoras sociales en Bogotá
Authors: Boada Reyes Carol Stephanny , Arévalo Sabogal Laura Daniela , López Acosta Nicolás
Published: November 2022

El emprendimiento social ha venido cobrando cada vez más fuerza como alternativa económica y de aporte para los sujetos y las comunidades, de allí que se revele la importancia de promover investigaciones que permitan identificar las condiciones y realidades que están presentes en este. Así, se describen a continuación las características de emprendedoras sociales con formación profesional alrededor de dos categorías: emprendimiento social y perfil del emprendedor social. Para esto se llevaron a cabo doce entrevistas a profundidad, en las cuales se hace evidente que una de las motivaciones más características de este tipo de emprendimiento es la conciencia social, dirigida a la transformación de las condiciones actuales de las comunidades. De otra parte, se encuentra como uno de los grandes desafíos la necesidad de formación; no solo para crear la oferta o servicio, sino también para fortalecer competencias administrativas, gerenciales y profesionales que favorezcan los resultados e impactos que se deriven.
Educación, empleo y satisfacción de necesidades en Colombia (2014). Propuesta de línea de base para el Marco Nacional de Cualificaciones
Authors: Sánchez Cárcamo Ricardo Antonio , Ramos Ruiz José Luis
Published: November 2022

El Marco Nacional de Cualificaciones como estrategia nacional de la validación de la experiencia adquirida (VEA) tiene por objetivo contribuir en el mejoramiento de las condiciones de vida de artesanos y otros oficios no titulados, bajo el supuesto de que la titulación permite a las personas mejorar sus condiciones de acceso a la formalidad y a la satisfacción de necesidades. Al respecto, no existe una metodología y una línea de base que permita dar un contexto y evaluar el impacto de la estrategia; por lo que la presente investigación busca subsanar estos dos vacíos en el Marco Nacional de Cualificaciones y así determinar en el largo plazoel impacto de dicha estrategia. Los resultados muestran que en Colombia en el 2014 hay un bajo nivel educativo y que a mayor nivel educativo mayor es la probabilidad de formalidad laboral y satisfacción de necesidades.
Série temporal de estudantes em dietas especiais inscritos no Programa Nacional de Alimentação Escolar da cidade de Macaé, Rio de Janeiro
Authors: De Souza Borges Natalia , De Carlos Santana Capelli Jane , Nascimento do Carmo Cléber , Sperandio Naiara , De Araújo Nunes Rosane , Medeiros Macedo da Rocha Camilla , Vieira Pontes Priscila , Silva Monteiro Luana
Published: November 2022

Objetivou-se neste estudo investigar a prevalência de patologias e a série temporal de estudantes em dietas especiais (DE) matriculados no Programa Nacional de Alimentação Escolar (PNAE) do município de Macaé/RJ, no octênio 2013-2020. Trata-se de um estudo descritivo, de base secundária, com dados obtidos de relatórios anuais disponibilizados pela Coordenadoria de Alimentação Escolar da Secretaria Municipal de Educação de Macaé, contendo informações de todos os estudantes em DE, matriculados na rede básica de ensino. Nos últimos oito anos, observaram-se 303.645 atendimentos realizados pelo PNAE, dos quais 3.310 estudantes (10,9/1.000 estudantes) receberam DE. Observou-se tendência crescente de estudantes em DE no período analisado (2013: 5/1.000 vs. 2020: 15,1/1.000), destacando-se a alergia à proteína do leite de vaca (2013: 35,5% vs. 2020: 42,2%) e a intolerância à lactose (2013: 34,3% vs. 2020: 12,7%). A restrição à lactose (2013: 9,3% vs. 2020: 14,5%), restrição às frutas (2013: 4,7% vs. 2020: 10,1%) e restrição às oleaginosas (2013: 0,6% vs. 2020: 6,0%) foram as restrições alimentares mais frequentes. Além disso, observou-se a tendência de aumento ao longo dos anos avaliados para restrição às oleaginosas (β1 = 0,094, p-valor = 0,001) e restrição às frutas (β1 = 0,099, p-valor = 0,001). Conclui-se que há prevalência ascendente de patologias e restrições alimentares bem como a tendência temporal de aumento de estudantes em DE.
Bioinformatic Analysis of the Genetic Mechanism of Biomineralization of Biogenic Magnetic Nanoparticles in Bacteria Capable of Tumor-Specific Accumulation
Authors: Gorobets Svitlana , Gorobets Oksana , Kovalova Svitlana
Published: November 2022

Background. Current methods of targeted cancer therapy are not always effective enough and can lead to side effects, such as an increased risk of autoimmune diseases. It is known that some bacteria are capable of specific accumulation in malignant tumors, and therefore can be used as an alternative means of targeted drug delivery. However, the genetic mechanism of tumor-specific accumulation of bacteria is not fully understood and needs to be studied in more detail.
Objective. This work aims to identify, by methods of comparative genomics methods, magnetically controlled bacteria among those for which tumor-specific accumulation has already been experimentally shown.
Methods. To identify magnetically controlled bacterial strains, i.e., bacteria that biomineralize biogenic magnetic nanoparticles (BMN), the method of comparative genomics was used, namely: pairwise alignment of proteomes with amino acid sequences of Mam-proteins of required for biomineralization of BMN in magneto­tactic bacteria Magnetospirillum gryphiswaldense MSR-1. Sequence alignments were performed in the BLAST program of the US National Center for Biotechnology Information (NCBI).
Results. The conducted bioinformatic analysis showed that strains of bacteria in which the ability to accumulate specifically in tumors has been experimentally proven are potential producers of BMN of different types. Among them there are potential producers of intracellular crystalline BMN, potential producers of intracellular amorphous BMN, and extracellular crystalline BMN
Conclusions. It is expedient to use bacteria-producing BMN as gene vectors and systems of targeted drug delivery to tumors that biomineralize BMN.
Медіація як альтернативний спосіб врегулювання конфліктів та інструмент державного управління
Authors: Чередніков Сергій
Published: November 2022

Протягом усієї історії людства конфлікти були і є невід’ємною частиною його існування. Залежності від багатьох обставин вони можуть вести до самих різноманітних наслідків: від потужного поштовху до змін та розвитку - до руйнування держав та колосальних  людських жертв. Переважна більшість соціально-політичних конфліктів  вирішуються силовими методами, хоча це, безумовно, спричиняє дуже великі втрат ресурсів: людських, часових, фінансових тощо. Тому актуальним є питання пошуку альтернативних методів врегулювання конфліктів...
Ефективність прийняття рішень органами влади в нових умовах реагування на кризові ситуації
Authors: Черниш Вадим
Published: November 2022

Пандемія коронавірусної хвороби виявила недосконалості систем публічного  управління багатьох країн і Україна не стала виключенням. Перші особи держав, національні уряди зіштовхнулись з необхідністю масштабного кризового управління, що охоплювало багато сфер функціонування суспільства та передбачало запровадження нових форм реагування на надзвичайні ситуації,  в тому числі і на міжнародному рівні...
Публічна влада в Україні в умовах пандемії COVID-19
Authors: Мануілова Катерина , Пурцхванідзе Ольга , Колеснікова Катерина
Published: November 2022

Сьогодні можна з упевненістю стверджувати, що за чисельністю жертв, масштабами захворювання коронавірусною інфекцією, а також значним негативним впливом на соціально-економічну сферу всіх держав світу спалах пандемії COVID-19 є найбільшим і безпрецедентним викликом у перших двох декадах XXI століття. Багатьом людям довелося змінити своє «доковідне»  життя й перейти на дистанційну форму роботи й освіти. Сьогодні у світі лишаються риторичними питання: Коли повернемся до традиційного «безкарантинного» повсякденного життя? або Повернімося ми до того життя, яке існувало до пандемії?..
Трансформація миротворчої діяльності ООН під час пандемії
Authors: Заєць Ольга , Багінський Андрій
Published: November 2022

Процес здійснення миротворчої діяльності є складним, тривалим, багатогранним та ресурсозатратним. Особливості його проведення потребують розроблення відповідного нормативно-правового механізму застосування, єдності місця та часу, чіткого дотримання поставлених цілей та контролю на всіх етапах їх виконання. Проте часто миротворчі місії зазнають непередбачуваних змін: загострення конфлікту між ворогуючими сторонами у свою чергу посилює рівень небезпеки перебування самих миротворців у зоні конфлікту, низького рівня залученості цивільного компоненту, неузгодженості військового та поліцейського компонентів [1]. Все це стає на заваді успішного виконання миротворчих та гуманітарних завдань. Та з часом з’являються нові траєкторії та нові виклики, формується інша, невідома досі, соціальна реальність, яка змушує трансформовувати правила миротворчої взаємодії та модернізовувати механізми її реалізації безпосередньо в ході мирних процесів. Таким чином у даному контексті відкритим залишається питання впливу пандемії COVID-19 на функціонування міжнародної миротворчості...
Розвиток організаційної культури в державній службі як чинник підвищення її ефективності
Authors: Куніцька Злата
Published: November 2022

На сучасному етапі свого розвитку державні служби багатьох країн зіткнулись з проблемою неефективного виконання своїх повноважень, що зумовило необхідність змінити стиль управління такими службами. Так організаційна культура наразі розглядається зовсім під іншим кутом – як засіб вимірювання продуктивності та ефективності цього управління. Вона безпосередньо пов’язана з розробкою та впровадженням систем вимірювання ефективності, а також з потенційним успіхом чи невдачею її використання...
Механізми професійної надійності фахівців у сфері публічного управління
Authors: Ложкін Георгій , Рибальченко Олег
Published: November 2022

Перш ніж отримати наукове трактування, поняття «надійність» мало свою передісторію. Так, наприклад, в українському тлумачному словнику надійна людина характеризується як вірна, яка вселяє довіру. Не змінюючи принципової сутності такого визначення, життєвий досвід привносить додаткове значення та відтінки в його зміст. Характеризуючи людину як надійну, зазвичай мають на увазі, що на неї можна покластися, що вона дотримується зобов'язань, домовленостей, обіцянок...
Публічне управління та COVID-19: виклики і цифрова трансформація
Authors: Чукут Світлана
Published: November 2022

COVID-19 став своєрідним каталізатором змін, які відбулися в прикореному темпі в публічному управлінні. Це зумовлено насамперед тим, що уряди були змушені в стислі терміни під тиском форс-мажорних обставин приймати свої рішення. До викликів, окреслених в цілях сталого розвитку ООН, додалися проблеми, зумовлені зростанням та поглибленням цифрового розриву, бідності, голоду та реальної загрози життю громадян. Як зазначає Ед Олово-Окере, директор глобальної практики управління Світового банку, найбільші виклики пов’язані зі ...
A Mixed Assessment for the Science Learning via a Bayesian Network Representation
Authors: Zhang Zhidong , Guanzon Angelica
Published: November 2022

This study explored an alternative assessment model to examine Chemistry learners’ progress. “The Assessment of Problem-Solving in Chemistry Learning” as a model represented students’ mastery of chemistry study. The data were from journaling narratives and analyzed through cognitive task analysis. Based on the analyses, a student model was established, which represents the qualitative information in a structure, and provides a potential framework of the assessment model for the quantitative representation—a Bayesian network assessment model. The student’s performance was assessed via the Bayesian network assessment model, and classified into three categories: low level, middle level, and high level. The mastery level should be at least scored at and above 90.51/100 for Declarative, Procedural, and Strategic Knowledge respectively.
"Through the library – to the development of society" II International forum. Republic of Tyva, August 16-17, 2022
Authors: Arakchaa A. K.
Published: November 2022

II Международный форум «Через библиотеку – к развитию общества», организаторами которого выступили Министерство культуры и туризма Республики Тыва, Национальная библиотека им. А. С. Пушкина Республики Тыва (НБ РТ), Тувинская библиотечная Ассоциация (БАРТ), состоялся 16–17 августа 2022 г. в Кызыле 1. Цель мероприятия: развитие международного и межрегионального сотрудничества библиотек, обобщение и ретрансляция передового опыта работы. В работе форума приняли участие более 400 участников (в том числе онлайн – 17) из библиотек и вузов культуры 20 субъектов Российской Федерации (РФ) и 3 стран ближнего зарубежья – Белоруссии, Казахстана и Узбекистана.
Effects of thymol:carvacrol association on health and zootechnical performance of tambaqui Colossoma macropomum
Authors: Frota Rebeca , Gallani Sílvia Umeda , Santos Paulo , Pereira Carolina , Oishi César , Gonçalves Lígia Uribe , Valladão Gustavo Moraes Ramos
Published: November 2022

Research in aquaculture shows that isomers thymol and carvacrol are extremely promising additives in fish diet, being classified as potent immunostimulant, antioxidant, and growth promoters. In this study, the effects of the thymol:carvacrol combination (1:1 ratio) on health parameters and zootechnical performance of tambaqui (Colossoma macropomum) were evaluated. The compounds were incorporated in concentrations of 0, 500, 1000, 1500, and 2000 mg/kg of feed. At intervals of 30 and 60 days, fish were sampled to evaluate haematological, biochemical, and immunological parameters, and after 60 days, zootechnical performance, parasitic load, and resistance to bacteriosis were evaluated. After 30 days, the fish that received the highest concentrations of thymol:carvacrol showed a reduction in the number of thrombocytes, a decrease in the number of lymphocytes, and an increase in eosinophils (p â"°¤ 0.05). After 60 days of feeding, haematological parameters were similar between all groups. Regarding the antiparasitic effect of the compounds, all groups that received supplemented diets had a high parasitic load (monogenean infestation) that did not differ from the control group. Regarding the prevention of bacteriosis, high mortality was detected in all groups after experimental challenge with Aeromonas jandaei, with no greater protection for fish fed with thymol:carvacrol. In conclusion, it was observed that the haematological results are different from those described in the literature of aquatic animals and corroborate with research of mammals. Therefore, the anti-inflammatory/immunosuppressive action of thymol and carvacrol are highlighted, which is relevant from a pharmaceutical and medicinal point of view. However, the use of these additives for aquaculture deserves to be discussed carefully, as the cost-benefit of this supplementation for the fish farmer is not a consensus.
Performance investigation of modular multilevel inverter topologies for photovoltaic applications with minimal switches
Authors: Parimalasundar E. , Kumar N. M. G. , Geetha P. , Suresh K.
Published: November 2022

Introduction. In recent years, a growing variety of technical applications have necessitated the employment of more powerful equipment. Power electronics and megawatt power levels are required in far too many medium voltage motor drives and utility applications. It is challenging to incorporate a medium voltage grid with only one power semiconductor that has been extensively modified. As a result, in high power and medium voltage settings, multiple power converter structure has been offered as a solution. A multilevel converter has high power ratings while also allowing for the utilization of renewable energy sources. Renewable energy sources such as photovoltaic, wind, and fuel cells may be readily connected to a multilevel inverter topology for enhanced outcomes. The novelty of the proposed work consists of a novel modular inverter structure for solar applications that uses fewer switches. Purpose. The proposed architecture is to decrease the number of switches and Total Harmonic Distortions. There is no need for passive filters, and the proposed design enhances power quality by creating distortion-free sinusoidal output voltage as the level count grows while also lowering power losses. Methods. The proposed topology is implemented with MATLAB / Simulink, using gating pulses and various pulse width modulation methodologies. Moreover, the proposed model also has been validated and compared to the hardware system. Results. Total harmonic distortion, number of power switches, output voltage and number of DC sources are compared with conventional topologies. Practical value. The proposed topology has been very supportive for implementing photovoltaic based multilevel inverter, which is connected to large demand in grid.
Photovoltaic system faults diagnosis using discrete wavelet transform based artificial neural networks
Authors: Bengharbi A. A. , Laribi S. , Allaoui T. , Mimouni A.
Published: November 2022

Introduction. This research work focuses on the design and experimental validation of fault detection techniques in grid-connected solar photovoltaic system operating under Maximum Power Point Tracking mode and subjected to various operating conditions. Purpose. Six fault scenarios are considered in this study including partial shading, open circuit in the photovoltaic array, complete failure of one of the six IGBTs of the inverter and some parametric faults that may appear in controller of the boost converter. Methods. The fault detection technique developed in this work is based on artificial neural networks and uses discrete wavelet transform to extract the features for the identification of the underlying faults. By applying discrete wavelet transform, the time domain inverter output current is decomposed into different frequency bands, and then the root mean square values at each frequency band are used to train the neural network. Results. The proposed fault diagnosis method has been extensively tested on the above faults scenarios and proved to be very effective and extremely accurate under large variations in the irradiance and temperature. Practical significance. The results obtained in the binary numerical system allow it to be used as a machine code and the simulation results has been validated by MATLAB / Simulink software.
INFLUENCE OF DETERMINATION ACCURACY OF THE BUILD STEP ON THE EFFICIENCY OF ADAPTIVE SLICING GROUP OF PRODUCTS FOR LAYERED MANUFACTURING
Authors: Garashchenko Yaroslav , Harashchenko Olena
Published: November 2022

Research results on improving the efficiency of the developed algorithm for adaptive layer-by-layer dissection are presented on the example of 3D models group placed in the workspace of an additive setup. This algorithm for 3D model adaptive cutting allows you to increase the productivity of the process and adjust the accuracy of manufacturing products, taking into account their geometry, by setting a rational value of the variable building step for each individual lowering of the work platform. Building step is calculated taking into account the distribution of the direction of surfaces normal of products group (relative to the construction direction) that fall into the current layer. The developed algorithm provides for some truncation of this distribution, which makes it possible to further increase the building step and, accordingly, reduce the number of layers. Thus, conditions can be created for rational support and given reduction in building time. This achieves a reduction in building time compared to existing strategies for variable dissection. Estimate of efficiency of adaptive layer-by-layer dissection was carried out taking into account the accuracy of determining (setting) building step in relation to 5 options for placing 3D models of industrial products in workspace. Comparative analysis of dissection options was performed by the number of layers and assessment of deviations from of surfaces correct shape. Increase in the efficiency of layer-by-layer shaping process with increased accuracy in determining variable step of building a group of complex products placed in workspace of installation has been revealed. This research was developed at the Department of "Integrated Technologies of Mechanical Engineering" named after M. Semko of NTU "KhPI".
Pengaruh Pandemi Covid Terahadap Penerimaan Pajak di Negara Indonesia pada Tahun 2020
Authors: Baitus Salamah  , Imahda Khoiri Furqon
Published: November 2022

Pajak merupakan sumber utama penerimaan Negara yang menyumbang sekitar 70% dari seluruh penerimaan pajak. Tanpa pajak, sebagian besar kegiatan Negara akan sulit untuk dilaksanakan. Penggunaan pajak mulai dari belanja pegawai sampai dengan pembiayaan berbagai proyek pembangunan. Karena itu, pajak merupakan ujung tombak pembangunan sebuah Negara. Sehingga sudah sepantasnya ssbagai warga Negara yang baik untuk taat membayar pajak. Pemerintah Indonesia sudah memberikan kemudahan kepada masyarakat untuk membayar pajak.

Artikel ini akan membahas mengenai dampak dari pandemi covid. Pandemi covid yang melanda hampir semua Negara didunia termasuk Indonesia ini membawa dampak buruk yang sangat banyak. Seperti pembatalan penerbangan domestic dan internasional, menurunnya jumlah wisata asing yang berkunjung ke Indonesia, penurunan okupansi hotel, kehilangan sector layanan udara, kontraksi PMI Manufacturing Indonesia yang cukup dalam hingga 4,3 atau lebih rendah dibandingkan tahun lalu, meluasnya PHK menyebabkan angka pengangguran menambah, dampak inflasi sehingga merosotnya nilai tukar uang, turunnya daya beli masyarakat,berkurangnya investasi, berkurangnya ekspor dan impor. Hal tersebut juga mengakibatkan turunnya penghasilan masyarakat maupun perusahaan sehingga berdampak turunnya penerimaan dari pajak penghasilan.
Pengaruh Leverage dan Arus Kas Operasi Terhadap Kualitas Laba Melalui Persistensi Laba
Authors: Iffat Fakhriyyah As’ad  , I Gusti Ketut Agung Ulupui  , Tri Hesti Utaminingtyas
Published: November 2022

Tujuan penelitian ini adalah untuk menganalisis pengaruh leverage dan arus kas operasi terhadap kualitas laba dengan persistensi laba sebagai variabel intervening. Penelitian ini menggunakan sampel perusahaan barang konsumsi yang terdaftar di Bursa Efek Indonesia selama tahun 2015 – 2020. Metode sampling yang digunakan dalam penelitian ini adalah purpusive sampling. Alat analisis yang digunakan dalam penelitian ini adalah aplikasi Smart PLS 3.0 for windows. Hasil yang diperoleh dari penelitian ini menunjukan bahwa leverage berpengaruh negatif terhadap persistensi laba, arus kas operasi berpengaruh positif terhadap persistensi laba, persistensi laba berpengaruh positif terhadap kualitas laba, leverage berpengaruh positif tidak signifikan terhadap kualitas laba, arus kas operasi berpengaruh negatif tidak signifikan terhadap kualitas laba. Lebih lanjut leverage dan arus kas operasi memiliki pengaruh tidak langsung terhadap kualitas laba melalui persistensi laba.
Lag exponential synchronization of fractional-order complex-valued dynamical networks with multiple delays via adaptive control
Authors: Ding Dawei , Wang Ya , Hu Yongbing , Yang Zongli , Zhang Hongwei , Zhang Xu
Published: November 2022

In this paper, the lag exponential synchronization issue of fractional-order complex-valued dynamic networks with multiple delays is studied. Considering the uncertain factors in the networks, a system model with uncertain disturbance and coupling strength is established. In addition, in order to study the dynamic behavior of complex networks under different coupling delays, symmetric and un symmetric matrices are used to model the coupling systems, respectively. By using Lyapunov stability theorem and fractional-order theory, the criterion of lag exponential synchronization of complex networks via adaptive control are obtained. The result extends the single delay problem of fractional-order complex-valued systems to multiple delays. Finally, two examples of fractional-order complex-valued systems are given to verify the correctness of the theoretical derivation.
Intraabdominal hypertension and abdominal compartment syndrome in children and adolescents: results of a follow-up survey among pediatric intensivists
Authors: Wiegandt Paul , Jack Thomas , Gise Alexander , Seidemann Kathrin , Böhne Martin , Köditz Harald , Beerbaum Philipp , Sasse Michael , Kaussen Torsten
Published: November 2022

Background:Constantly elevated intra-abdominal pressure (IAH) can lead to abdominal compartment syndrome (ACS), which is associated with organ dysfunction and even multiorgan failure. Our 2010 survey revealed an inconsistent acceptance of definitions and guidelines among pediatric intensivists regarding the diagnosis and treatment of IAH and ACS in Germany. This is the first survey to assess the impact of the updated guidelines on pediatric intensive care units (PICU) after WSACS published those in 2013.Methods:We conducted a follow-up survey and sent 473 questionnaires to 328 German- speaking pediatric hospitals. We compared our findings regarding awareness, diagnostics and therapy of IAH and ACS with the results of our 2010 survey.Results:The response rate was 48% (n=156). The majority of respondents was from Germany (86%) and working in PICUs with mostly neonatal patients (53%). The number of participants who stated that IAH and ACS play a role in their clinical practice rose from 44% in 2010 to 56% in 2016. Similar to the 2010 investigations, only a few pediatric intensivists knew the correct WSACS definition of an IAH (4% vs 6%). Different from the previous study, the number of participants who correctly defined an ACS increased from 18% to 58% (p<0,001). The number of respondents measuring intra-abdominal pressure (IAP) increased from 20% to 43% (p<0,001). Decompressive laparotomies (DLs) were performed more frequently than in 2010 (36% vs. 19%, p<0,001), and the reported survival rate was higher when a DL was used (85%± 17% vs. 40± 34%).Conclusions: Our follow-up survey of pediatric intensivists showed an improvement in the awareness and knowledge of valid definitions of ACS. Moreover, there has been an increase in the number of physicians measuring IAP in patients. However, a significant number has still never diagnosed IAH/ACS, and more than half of the respondents have never measured IAP. This reinforces the suspicion that IAH and ACS are only slowly coming into the focus of pediatric intensivists in German-speaking pediatric hospitals. The goal should be to raise awareness of IAH and ACS through education and training and to establish diagnostic algorithms, especially for pediatric patients. The increased survival rate after conducting a prompt DL consolidates the impression that the probability of survival can be increased by timely surgical decompression in the case of full-blown ACS.
Community Health Teams: A Qualitative Study about the Factors influencing the Decision-Making Process for Resource Allocation
Authors: Natkin Lisa W. , Broek-Altenburg Eline van den , Benson Jamie S. , Atherly Adam
Published: November 2022

Background: The purpose of this study was to explore the contextual factors influencing how individual Community Health Teams make decisions about what services to offer and how to allocate their resources.
Methods: We conducted thirteen semi-structured interviews with Community Health Team (CHTs) leaders between January to March, 2021. We analyzed interviewees descriptions of their service offerings, resources allocation, and decision-making process to identify themes.
Results: Four major themes emerged from the interview data as contextual factors influencing community health team program managers’ decision-making process: commitment to offering high quality care coordination, Blueprint’s stable and flexible structure, use of data in priority setting, and leveraging community partnerships and local resources.
Conclusions: Community based CHTs with flexible funding allowed programs to tailor service offerings in response to community needs. It is important for teams to have access to community level data. Teams are cultivating and leveraging community partners to increase their care coordination capacity, which is focus of their work. CHTs are a model for leveraging community partnerships to increase service capacity and pubic engagement in health services for other states to replicate.
An insight investigation to the antiurolithic activity of Trachyspermum ammi using the in vitro and in vivo experiments
Authors: Khan Aslam , Gilani Anwarul-Hassan
Published: November 2022

The crude extract of Trachyspermum ammi seeds (Ta.Cr) was studied for its antiurolithic activity using the in vivo and in vitro experiments. In the in vivo experiments, Ta.Cr treatment showed a diuretic activity at the dose of 30 and 100 mg/kg and exhibited curative effect in male hyperoxaluric Wistar rats, which received 0.75% ethylene glycol (EG) in drinking water given for 3 weeks, with 1% ammonium chloride (AC) for initial three days. In the in vitro experiments, Ta.Cr delayed the slopes of nucleation and inhibited the calcium oxalate (CaOx) crystal aggregation in a concentration-dependent manner like that of Potassium citrate. Ta.Cr also inhibited DPPH free radicals like standard antioxidant drug butylated hydroxytoluene (BHT), and significantly reduced cell toxicity and LDH release in Madin-Darby canine kidney (MDCK) cells, exposed to oxalate (0.5 mM) and COM (66 µg/cm2) crystals. In isolated rabbit urinary bladder strips, Ta.Cr relaxed High K+ (80mM) and CCh (1 µM)-induced contractions, showing antispasmodic activity. The findings of this study suggest that the antiurolithic activity of crude extract of Trachyspermum ammi seeds may be mediated by a number of mechanisms, including a diuretic, an inhibitor of CaOx crystal aggregation, an antioxidant, renal epithelial cell protection, and an antispasmodic. Thus, showing therapeutic potential in urolithiasis, for which there is no viable non-invasive option in modern medicine.
Behavioural change interventions encouraging clinicians to reduce carbon emissions in clinical activity: A systematic review
Authors: Batcup Carys , Breth-Petersen Matilde , Dakin Thomas , Barratt Alexandra , McGain Forbes , Newell Ben , Pickles Kristen
Published: November 2022

Background
Clinical activity accounts for 70–80% of the carbon footprint of healthcare. A critical component of reducing emissions is shifting clinical behaviour towards reducing, avoiding, or replacing carbon-intensive healthcare. The objective of this systematic review was to find, map and assess behaviour change interventions that have been implemented in healthcare settings to encourage clinicians to reduce greenhouse gas emissions from their clinical activity.
Methods
Studies eligible for inclusion were those reporting on a behaviour change intervention to reduce carbon emissions via changes in healthcare workplace behaviour. Six databases were searched in November 2021 (updated February 2022). A pre-determined template was used to extract data from the studies, and risk of bias was assessed. The behaviour change techniques (BCTs) used in the interventions were coded using the BCT Taxonomy.
Results
Six full-text studies were included in this review, and 14 conference abstracts. All studies used a before-after intervention design. The majority were UK studies (n = 15), followed by US (n = 3) and Australia (n = 2). Of the full-text studies, four focused on reducing the emissions associated with anaesthesia, and two aimed at reducing unnecessary test ordering. Of the conference abstracts, 13 focused on anaesthetic gas usage, and one on respiratory inhalers. The most common BCTs used were social support, salience of consequences, restructuring the physical environment, prompts and cues, feedback on outcome of behaviour, and information about environmental consequences. All studies reported success of their interventions in reducing carbon emissions, prescribing, ordering, and financial costs; however, only two studies reported the magnitude and significance of their intervention’s success. All studies scored at least one item as unclear or at risk of bias.
Conclusion
Most interventions to date have targeted anaesthesia or pathology test ordering in hospital settings. Due to the diverse study outcomes and consequent inability to pool the results, this review is descriptive only, limiting our ability to conclude the effectiveness of interventions. Multiple BCTs were used in each study but these were not compared, evaluated, or used systematically. All studies lacked rigour in study design and measurement of outcomes.
Other
The study was registered on Prospero (ID number CRD42021272526).1
Evaluating the potential of a hybrid baffled reactor for simultaneous organic matter and nitrogen removal of dairy wastewater
Authors: Lucio Danilo S. G. , Dias Maria Eduarda S. , Ribeiro Rogers , Tommaso Giovana
Published: November 2022

This work designed and assessed the performance of a structured-bed hybrid baffled reactor (SBHBR) with anaerobic/anoxic chambers, treating different dairy wastewater. The anoxic chambers in SBHBR were exposed to intermittent aeration for the simultaneous removal of organic matter and total nitrogen (TN) under a low COD/TN ratio. The hydraulic retention time (HRT) in SBHBR was 48h, with 16.3h in the anoxic zone, where intermittent aeration was implemented, consisting of 60 minutes of aeration and 30 minutes without aeration. The COD/TN ratios tasted were 2.1 ± 0.6, 0.84 ± 0.5, and 0.35 ± 0.1 in the inlet of the anoxic chambers. The SBHBR provided COD removal efficiencies above 90% in all experimental stages. The relevant results achieved in this research regarding carbon and nitrogen removal efficiencies were obtained in stage III. The SBHBR achieved a TN removal efficiency of 82.3 ± 11.4% during this stage. The nitrification and denitrification efficiencies were 85.9 ± 17% and 85.2 ± 9%, respectively, resulting in the anoxic zone TN removal efficiency of 74.6 ± 14.7% with a C/N ratio of 0.35 ± 0.1. Stoichiometric calculations based on nitrogen removal and the C/N ratio required by the denitrification process were used to corroborate the activity of bacteria that perform the anammox pathways as their main mechanism.
Synthesis of three new macroacyclic Schiff base complexes and the investigation of their anticancer, antioxidant and antibacterial properties: theoretical and solid state structures
Authors: keypour Hassan , hajari saadat , yaghoobi fereshteh , rezaei mohammadtaher , farida seyed hamed moazzami , saadati masoud , Gable Robert
Published: November 2022

Three symmetrical macroacyclic Schiff base complexes were prepared from a ligand derived from the condensation reaction of 1,4-bis(2-Aminophenyl)piperazine and salicylaldehyde (L) with Cu(II), Ni(II) and Co(II) perchlorates. The ligand and the Schiff base complexes were characterized by elemental analyses, FT-IR and mass spectrometry, with the structure of [CoL] being determined by a single crystal X-ray structural analysis. In this complex, the cobalt is in a distorted trigonal prismatic coordination environment, surrounded by the six donor atoms of the deprotonated hexadentate ligand. In order to compare the experimental and theoretical data and determine structure parameters in all complexes, Density Functional Theory (DFT) calculations at the B3lyp and BP86 levels with Def2-TZVP basis set have been carried out. NBO and QTAIM analyses have been used to describe the nature of M-O and M-N bonding in these complexes. The synthesized complexes were screened for their antioxidant activities using the DPPH free radical scavenging assay while their bactericidal activity was evaluated by the paper disc diffusion method against both Gram-negative and Gram-positive bacteria, revealing strong antioxidant activities and moderate effectiveness against all bacteria tested. The cytotoxicity of the metal complexes was also investigated against AGS (gastric) and A549 (lung) adenocarcinoma cells.
Stochastic Gradient Descent for Optimization of Nuclear Systems
Authors: Williams Austin , Walton Noah , Maryanski Austin , Bogetic Sandra , Hines Wes , Sobes Vladimir
Published: November 2022

The use of gradient descent methods for optimizing k-eigenvalue nuclear system has been shown to be useful in the past, but the k-eigenvalue gradients have proved challenging due to their stochastic nature and uncertainty. ADAM is a gradient descent method that accounts for gradients with a stochastic nature. This analysis uses challenge problems constructed to verify if ADAM is a suitable tool to optimize k-eigenvalue systems. ADAM is able to successfully optimize nuclear systems using the gradients of k-eigenvalue problems despite their stochastic nature and uncertainty.
Rapid degeneration of iPSC-derived motor neurons lacking Gdap1 engages a mitochondrial-sustained innate immune response
Authors: Torres Josema , Leon Marian , Prieto Javier , Navarro Maria Micaela Molina , Garcia Francisco , Barneo-Muñoz Manuela , Ponsoda Xavier , Saez Rosana , Palau Francesc , Dopazo Joaquin , Belmonte Juan Carlos Izpisua
Published: November 2022

Charcot-Marie-Tooth disease is a chronic hereditary motor and sensory polyneuropathy targeting Schwann cells and/or motor neurons. Its multifactorial and polygenic origin portrays a complex clinical phenotype of the disease with a wide range of genetic inheritance patterns. The disease-associated gene GDAP1 encodes for a mitochondrial outer membrane protein. Mouse and insect models with mutations in Gdap1 have reproduced several traits of the human disease. However, the precise function in the cell types affected by the disease remains unknown. Here, we use induced-pluripotent stem cells derived from a Gdap1 knockout mouse model to better understand the molecular and cellular phenotypes of the disease caused by the loss-of-function of this gene. Gdap1-null motor neurons display a fragile cell phenotype prone to early degeneration showing 1) altered mitochondrial morphology, with an increase in the fragmentation of these organelles, 2) activation of autophagy and mitophagy, 3) abnormal metabolism, characterized by a downregulation of Hexokinase 2 and ATP5b proteins 4) increased reactive oxygen species and elevated mitochondrial membrane potential, and 5) increased innate immune response and p38 MAP kinase activation. Our data reveals the existence of an underlying Redox-inflammatory axis fueled by altered mitochondrial metabolism in the absence of Gdap1. As this biochemical axis encompasses a wide variety of druggable targets, our results may have implications for developing therapies using combinatorial pharmacological approaches and improving therefore human welfare.
Better to be the head of a dog or the tail of a lion? Revisiting the double-edged sword model of college students' perceived overqualification
Authors: Pan Runsheng , Hou Zhijin , Wang Danni , Liu Beibei
Published: November 2022

School psychologists are always concerned about underperforming students; however, a recent study calls attention to a group of college students who believe themselves to outperform other students while also worrying about their futures: students who perceive themselves to be overqualified (POQ) (Wang et al., 2022). In this study, we revisited the double-edged sword model of college students’ POQ by untangling the mediating mechanism between POQ, learning engagement, and the life satisfaction of college seniors. Two questionnaire surveys were conducted and attained somewhat different results from previous studies: 1. POQ positively predicted learning engagement via the mediation of career aspiration and performance-approach goals, but not performance-avoidance goals; 2. The positive effects of POQ on career aspirations, performance-approach goals, and learning engagement were weakened by a growth mindset; 3. The relationship between POQ and life satisfaction was nonsignificant, relative deprivation negatively mediated this relationship while general self-efficacy positively mediated this relationship. These findings enriched our understanding of how POQ affect college students’ learning and living and provided evidence that growth mindset is less beneficial for members of advantaged groups in academic settings. Based on our findings, we offered practical suggestions regarding POQ students in colleges.