bluuebunny/crossref_metadata_2025 huggingface dataset:
How good is the government? Analysis of west java’s local government disclosure through an integrated reporting framework
Authors: Pratama Arie , Afiah Nunuy Nur , Alfian Adhi
Published: May 2023

The present study aims to determine the level and quality of comprehensive performance disclosure of the West Java government of Indonesia using an integrated reporting framework. The study analyzes the disclosure of government performance information based on the Notes to the Financial Statements of 27 districts/city governments and one provincial government in the West Java region from 2016–2020. The data was obtained by conducting a content analysis of the government's financial statements using the integrated reporting quality disclosure matrix. Data were analyzed using descriptive statistics, non-parametric tests, and a cluster analysis. The results indicate that: (1) the quality of disclosure in government financial statements according to the integrated reporting framework is still low, with an average score of 35.19%; (2) there is no difference in the scores of disclosure items between district and city governments, but there is an increase in disclosure per year for two elements and total disclosure; and (3) the cluster formed indicates that 22 of 28 district and city governments need to improve the quality of their disclosures. In general, the disclosure quality of the West Java government’s financial statements is still at a low level. The results indicate the need to improve the quality of financial reporting by the government and the use of integrated reporting as a frame of reference.
Iranian specialists’ approach to treatment escalation in multiple sclerosis patients with cognitive impairment
Authors: Ghadiri Fereshteh , Asadollahzadeh Elnaz , Ebadi Zahra , Sahraian Mohammad Ali , Azimi Amirreza , Navardi Samira , Heidari Hora , Abna Zohreh , Aboutorabi Marzieh , Adibi Iman , Baghbanian Seyed Mohammad , Paybast Sepideh , Poursadeghfard Maryam , Hosseini Samaneh , Shahmohammadi Sareh , Ghaffari Mehran , Ghalyanchi-Langroodi Hamidreza , Ghiasian Masoud , Kamali Hoda , Kouchaki Ebrahim , Mahrabi Farzad , Mohammadianinejad Ehsan , Nahayati Mohammad Ali , Moghadasi Abdorreza Naser
Published: May 2023

Background: People with multiple sclerosis ‎(MS) and their physicians recognize cognitive retention as an important desired outcome of disease-modifying
Iranian MS experts regarding the treatment approach toward clinical cases with different physical and cognitive conditions.
Methods: Opinions of 20 MS specialists regarding the best approach to 6 case scenarios (with different clinical, cognitive, and imaging characteristics) were gathered via a form.
Results: The estimated kappa of 0.16 [95% confidence interval (CI): 0.159-0.163; P < 0.001] suggested a poor degree of agreement on the treatment choice among the professionals.
Conclusion: Although most specialists agreed with treatment escalation in cases with cognitive impairment, there was no general agreement. Furthermore, there was not enough clinical evidence in the literature to develop consensus guidelines on the matter.
Association analysis of serotonin transporter gene polymorphism among the South-Indian migraineurs
Authors: Kesavan Pallavi , Padmaja Satheesh Aiswarya , Rehman Syed Rasheed Akram Husain , Veerappan Umamaheshwari , Kannaian Subramaniyan , Veerabathiran Ramakrishnan
Published: May 2023

Background: Migraine is a multifactorial neurological disorder characterized by frequent moderate to severe intensity headaches. The genetic variations in synaptic and post-receptor signalling proteins have direct effect on the process of serotonergic neurotransmission.
Methods: We aimed to investigate the genetic association of serotonin transporter (SERT) 5-hydroxytryptamine transporter-linked promoter region (5-HTTLPR) polymorphism and migraine risk in South-Indian population. A total of 304 subjects with migraine including with aura (MA) and without aura (MO) and 308 controls were included in the present study. The single nucleotide polymorphism (SNP) was detected using polymerase chain reaction (PCR) and confirmed by deoxyribonucleic acid (DNA) sequencing.
Results: The genotyping analysis revealed insignificant relationship with migraine subjects when compared with controls (P > 0.05). The minor ‘S’ allele showed no association with odds ratio (OR) = 1.23 [95% confidence interval (CI): 0.90-1.66], heterozygote with OR = 1.18 (95% CI: 0.82-1.69), and homozygote with OR = 1.51 (95% CI: 0.52-4.35).
Conclusion: Further clinical studies are required to validate the results of SERT 5-HTTLPR promoter polymorphism in diverse ethnic descents especially in Asian populations.
The prevalence of multiple sclerosis in Tehran, Iran, in 2020
Authors: Eskandarieh Sharareh , Ayoubi Saeideh , Sahraian Mohammad Ali
Published: May 2023

The Article Abstract is not available.
Surface Micro-Hardness and Wear Resistance of a Self-Adhesive Flowable Composite in Comparison to Conventional Flowable Composites
Authors: Azizi Fateme , Ezoji Fariba , Khafri Soraya , Esmaeili Behnaz
Published: May 2023

Objectives: The durability of composite restorations is directly affected by the mechanical properties of the composite. The aim of this study was to evaluate the hardness and wear resistance of self-adhesive flowable composite (SAF) in comparison with conventional flowable composites.
Materials and Methods: In this in vitro study, 50 composite specimens were prepared in brass molds with 10mm ×10mm ×2mm and divided into five groups (n=10). Specimens included three conventional flowable composites (Grandio flow, Filtek flow and Admira fusion flow), one self-adhering flowable composite (SAF, Vertise flow) and a microhybrid composite (filtek z250). After polishing, the micro-hardness of the specimens was measured in a Vickers hardness device, and the specimens were then subjected to 5000, 10000, 20000, 40000, 80000 and 120000 wear cycles in a wear tester. One-way ANOVA/Games-Howell, Kruskal Wallis, and Friedman tests were used for statistical analysis. The significance level was set at P<0.05.
Results: The surface micro-hardness of the SAF was significantly lower than that of the microhybrid composite (P=0.01). There was no significant difference between the surface hardness of the different tested flowable composites (P>0.05). Also, the wear resistance of the studied composites was not significantly different in various cycles (P>0.05).
Conclusion: Based on our results, SAF would not be an ideal substitute for conventional flowable composites in high-stress areas.
Microtensile Bond Strength of Different Bonding Agents to Superficial and Deep Dentin in Etch-and-Rinse and Self-Etch Modes
Authors: Sharifian Atefe , Esmaeili Behnaz , Gholinia Hemmat , Ezoji Fariba
Published: May 2023

Objectives: This study aimed to assess the microtensile bond strength (µTBS) of etch-and-rinse (E&R), self-etch (SE), and universal adhesives to superficial and deep dentin.
Materials and Methods: In this in vitro study, 40 sound third molars were randomly divided into two main groups of superficial and deep dentin. Based on our classification, superficial dentin was right beneath the deepest occlusal groove, and deep dentin was 2mm beneath the deepest occlusal groove. Each group was divided into 4 subgroups (n=20) for application of Adper Single Bond 2 (ASB), Clearfil SE Bond (CSE), and Scotchbond Universal (SBU) in E&R and SE modes along with Charisma Smart composite resin on dentin. The specimens were incubated in distilled water at 37°C for 24 hours and their µTBS was then measured. The mode of failure was determined under a stereomicroscope at ×40 magnification. Data were analyzed by one-way ANOVA (alpha=0.05).
Results: The highest µTBS belonged to the superficial dentin/SBU/E&R group. The µTBS was significantly higher in superficial dentin than deep dentin for all adhesives (P=0.005). There was no significant difference in mode of failure among the groups.
Conclusion: Based on the results obtained in the present study, type of bonding agent and application mode affected µTBS. In use of universal adhesive, E&R mode can improve µTBS.
Bone Cement Emboli after Arthroplasty: Is It Possible? A Case Report and Literature Review
Authors: Kazemi Seyyed-Morteza , Keyhani Sohrab , Miniator Sajjadi Mohammadreza , Etemadi Ramin , Hosseininejad Seyyed-Mohsen , Nouri Hoda
Published: May 2023

Background: Polymethylmethacrylate (PMMA) has been extensively used as bone cement in orthopedic procedures. Pulmonary cement embolisms (PCEs) are supposed to originate from cement extravasation into the basivertebral veins before draining into the inferior vena cava and eventually becoming lodged in the pulmonary capillaries. Few cases of bone cement embolism have been reported. This study reported a case of pulmonary embolism (PE) after thoracolumbar fixation and kyphoplasty and reviewed the current literature.
Case Report: We presented an 81-year-old woman who had undergone thoracolumbar vertebroplasty three months before admission and became symptomatic due to PE after total knee arthroplasty (TKA).
Conclusion: This case illustrates that clinicians must be aware of the probable occurrence of respiratory distress syndrome in patients with a history of vertebroplasty.
Effect of Metformin Monotherapy and Combination Therapy with Glimepiride on Lipid Profile in Drug Naive Type-2 Diabetes Patients: A Prospective Observational Study
Authors: Anchit  , Bhushan Aruna , B Srinivasa
Published: May 2023

Background: Dyslipidemia is an important risk factor for development of macrovascular disease. Altered lipid metabolism and abnormality in serum lipid profile results atherogenic dyslipidemia this can worsen the prognosis of diabetic patients and increases risk of cardiovascular disease and stroke.  This study aims to evaluate the effect of metformin monotherapy and combination therapy with glimepiride on lipid profile of drug naive type-2 diabetes patients after 10-12 weeks of treatment.
Methods: In this study, prescriptions of 120 OPD (Outpatient department) patients of drug naive type-2 diabetes were collected. The detailed observation of: demographic, drug details and investigations done were noted in a specially designed preform. The data was analyzed statistically and results were expressed as numbers and percentage.
Results: The total of 120 patients prescriptions was analyzed. Among these male was 62.5% and female were 37.5%, most common affected age group was between 31-50 years with mean age of 43.82 yrs. Metformin was most commonly prescribed drug 42% followed by its combination with glimepiride 58%. Average blood glucose level prior therapy was 193.4mg/dl and post therapy it was 135.2mg/dl. After 10-12 weeks of metformin monotherapy and combination therapy with glimepiride LDL was significantly reduced from 92.3mg/dl to 83.2mg/dl, TG was reduced from 145.5mg/dl to 132 mg/dl and HDL increased from 29.1 mg/dl to 32.9 mg/dl.
Conclusion: Metformin monotherapy and combination therapy with glimepiride appreciably improved dyslipidemia in drug naive type-2 diabetes patients.
Clustering of Deceased Patients with COVID-19 in Iran Based on Clinical Features in Hospitalization
Authors: Shaseb Elnaz , Ghaffary Saba , Vaez Haleh , Sarbakhsh Parvin , Khani Elnaz
Published: May 2023

Background: Effective clinical care and identifying susceptibility to COVID-19-related mortality requires rapid recognition of risk factors and their relations with disease outcomes. This study aimed to cluster and identify various subgroups of COVID-19 patients and examine the relationship between these subgroups and the causes of death.
Methods: This retrospective study assessed the risk factors contributing to COVID-19 patients’ death (n = 128) by evaluating deceased patients' demographic, clinical, and laboratory features and clustering various subgroups of individuals to investigate any correlation.
Results: The mean age of deceived patients was 69.7 years, and the majority of them were male (65.6%). The levels of blood urea nitrogen, creatinine, alkaline phosphatase, erythrocyte sedimentation rate, lactate dehydrogenase, and C-reactive protein were high at admission and increased during the hospitalization. Shortness of breath (68%) and cough (62.5%) were the most common symptoms, and hypertension (50.8%) was the most common comorbidity among deceased patients. The clustering quality based on the underlying disease and symptoms was not acceptable. However, clustering based on vital signs showed significant differences in body temperature, pulse rate, respiratory rate and oxygen saturation (P<0.001). Furthermore, disseminated intravascular coagulation (DIC) was significantly higher in patients with weaker vital signs than those with better vital signs (15.36% vs. 0.0% P = 0.002).
Conclusion: Older age, male sex, hypertension, and high inflammatory markers might be the risk factors for COVID-19-related mortality. Furthermore, considering that patients with poor vital signs were susceptible to develop DIC, prevention of these consequences might be helpful in COVID-19 management.
Pharmacological Approach for Prevention of Bleomycin-Induced Lung Injury
Authors: Ayoubifar Mohammad , Abedi Farshad , Moeini Nodeh Mohammad , Arasteh Omid
Published: May 2023

Bleomycin is a chemotherapeutic medication commonly use in the treatment of Hodgkin's disease and germ cell tumors. Pulmonary fibrosis is major and dose limiting adverse effect of the drug. There is not currently any equal alternative approach or a medical agent for prevention of its pulmonary injury. We searched scientific databases in order to find investigational pharmacologic medicines in prevention of bleomycin-induced lung toxicity (BILI). Results revealed that some anti-inflammatory and antioxidant preparations such as statins, N-acetylcysteine (NAC), supplements (vitamin D3, L-arginine, selenium), and renin-angiotensin-aldosterone system (RASS) inhibitors might be effective in preclinical models of pulmonary toxicity mediated by bleomycin. However, we still need more in vivo studies and large human randomized clinical trials to confirm their benefits.
Military Culture: Philosophical and Anthropological Perspective of Research
Authors: Ivanov Vladimir N.
Published: May 2023

The article is devoted to the presentation and analysis of the philosophical and anthropological approach to the study of the phenomenon of military culture. The paper shows that the study of this phenome-non in the domestic humanities began at the turn of the 20th-21st centuries. Prior to this, the attempts made were episodic in nature and focused mainly on the ideological component of military culture, i.e. her spiritual element. The relative recentness of the beginning of the study of this phenomenon in a philosophical perspec-tive explains its poor study and the presence in humanitarian knowledge, in general, of different approaches to the definition of the analyzed concept. The paper concludes that the previously used approaches to the study of military culture (as a denotation) - psychological, sociological, semiotic and normative - are limited. The presented article shows how the philosophical and anthropological approach overcomes these shortcomings and at the same time takes into account the specifics of each of the presented ones. To sum up above written, a conclusion is made about the effectiveness of the application of the philosophical and anthropological method to the study of military culture.
On the Role of a Religious Symbol in the Study of the Essence of Human: Paul Ricoeur
Authors: Ivanova Anna I.
Published: May 2023

This article gives an interpretation of some religious and symbolic concepts presented by the French philosopher P. Ricoeur as the most significant in the study of the issue of human essence. Based on the works of P. Ricoeur, the necessity of rethinking ethical categories, which were previously considered only from religious positions, is substantiated. The article reveals a number of problematic aspects of the herme-neutical understanding of the religious text. The relevance of the study is due to the fact that the essence of man as a methodological problem needs a modern interpretation, and we find its most interesting reading in the works of P. Ricoeur. Through the prism of multidirectional, well-established and most significant, key philosophical trends, Ricoeur proposes to rethink the problem of man in a new way. The discourse of religion is one of the fundamental in philosophical reflection. Therefore, we present it possible to comprehend the essence of a person through a religious sym-bol, which has a significant impact on the formation of his self and spiritual individuality. By delving into the essence of key symbolic aspects of the Christian religion, we shape our own experience through the interpre-tation of ethically significant concepts such as freedom and hope, guilt and consolation. In the process of interpreting the Scriptures, considering the problem of correlation of the Testaments, the researcher approaches self-understanding and plunges into self-reflection, thanks to which he develops the product of his own worldview. This is the approach to the rational part of religion - logos.
Evolution Issue in a Modern Christian thought
Authors: Mamonov Vladimir V.
Published: May 2023

The article deals with the problem of perception of the theory of evolution in modern Christianity. The key texts on the topic are analyzed and the main approaches to the problem are considered, including theistic evolutionism, alterism, young-earth and old-earth creationism, process theology. Conclusions about the relevance of the problem are offered. The author also comes to the conclusion that the problem affects critical areas of Christian anthropology, theodicy, eschatology and Christology. The assessment of the degree of influence of the higher clergy on the predominance of one or another point of view on evolution within a particular denomination is given.
Features of the Provincial Policy of Emperor Hadrian
Authors: Gabarashvili Georgiy D.
Published: May 2023

The provincial policy of the Roman emperor Hadrian (117-138 AD) is considered. It is noted that the distinctive feature of Hadrian's policy, in comparison with previous emperors, was his travels, which allowed him to carry out reforms directly on the ground. It is assumed that Hadrian solved various tasks in the provinces of the East and West of the Empire. So, if in the East Hadrian paid more attention to his Philhellenic policy, then in the West to the military structure and strengthening of the borders of the empire. In addition, the features of the Hellenization of parts of the Roman Empire and the reasons for the spread of the cult of Antinous in the East are considered, as well as the most important events of Hadrian in the provinces during his travels. To study the issue, the works of foreign researchers were involved.
Ventricular Fibrillation in Acute Coronary Syndrome with Elevated ST Segment: Incidence and Predictive Factors.
Authors: ZOUZOU Hanane
Published: May 2023

Background: Ventricular fibrillation is the principal cause of sudden cardiac death; in acute coronary syndrome (ACS) with elevated ST segment, its incidence and predictive factors, have been the subject of several international studies; however, its epidemiological data is lacking in Algeria.
Aims: The main objective of our study is the determination of the frequency of ventricular fibrillation in acute coronary syndrome with elevated ST segment, the secondary objective was the analysis of predictive factors of this arrhythmia, and related mortality.
Methods and materials:  In this prospective study, conducted in the cardiology department of Hussein Dey hospital (Algiers-Algeria), 467 patients with acute coronary syndrome with elevated ST segment (87 women and 380 men) were enrolled between 28 February 2014 and 16 July 2015. The average age is 60 ± 13 years; at admission, a Holter recorder was attached for continuous ECG monitoring during 48 hours
Kruskal’s ANNOVA or H tests were used for comparison of quantitative variables, χ2 test or Fisher’s exact test, were used for qualitative variables, all tests were performed with 1st species risk of 5%.
Results:  The frequency of ventricular fibrillation is 5.8% (27 patients), CI 95%: [3.7%-7.9%], multivariate analysis identified the following independent predictors: low diastolic blood pressure: high ST segment elevation, large diastolic left and right ventricular diameters.
The risk of mortality expressed by Hazard Ration (HR) is 12.9 (CI 95%: [4.9-34], p < 0.001), the predictors of mortality are right ventricular failure and failure of thrombolysis.
Conclusion: Ventricular fibrillation is the principal cause of sudden cardiac death, during acute coronary syndrome with elevated ST segment, its predictive factors according to our study are: low diastolic blood pressure: high ST segment elevation, large diastolic left and right ventricular diameters, its occurrence increases the risk of hospital mortality, this high risk is partly explained by the therapeutic strategy.
«Nacionales» contra «disidentes». La prensa del Trienio Liberal y la caída del gobierno virreinal en el Perú (1821-1823)
Authors: Peralta Ruiz Víctor
Published: May 2023

A mediados del siglo veinte Melchor Fernández Almagro sostuvo la tesis acerca de la despreocupación de los gobernantes del liberalismo constitucional por lo que estaba ocurriendo en la América española en la fase decisiva de su independencia. En el caso del Perú, recordaba este historiador cómo el secretario interino de Guerra, Ignacio Balanzat, pronunció en su Memoria a las Cortes, a mediados de 1821, la atrasada noticia de que «las provincias del virreinato de Lima continúan pacíficas y unidas a la patria» (1944, p. 64). Esta aseveración acerca de la indiferencia fue refrendada y ampliada poco después por Jaime Delgado en su estudio sobre la independencia de América en la prensa española. Aseveró este que los periódicos liberales españoles entre 1820 y 1823 se dedicaron a proporcionar noticias peregrinas y disparatadas sobre la insurgencia americana con el exclusivo propósito de sostener la tesis unionista. Según Delgado la imposibilidad de la separación estaba garantizada por la «fuerza», «virilidad» e «ilustración común», virtudes que según los periodistas de esa época sobraban en los españoles y escaseaban en los americanos. De ahí que con relación a la crisis peruana en junio de 1821 «afirmaba [El Universal] que la situación de Lima —centro entonces de atención— era segura, especialmente desde la sustitución de Pezuela por la Serna, que había triturado el ejército de San Martín entre el entusiasmo general de la población limeña…» (1949, p. 261).
«Quedarán ya para el polvo y el olvido» : las elecciones a diputados a las Cortes españolas en el Perú, 1810-1824
Authors: Sala i Vila Núria
Published: May 2023

La influencia del liberalismo hispano en la construcción del republicanismo peruano ha sido abordada por diversos historiadores (Peralta, 2008), si bien carecemos aún de un balance global, pero sobre todo sigue pendiente reconstruir su alcance durante el Trienio Liberal. Uno de los aspectos de cierta centralidad fue la representación peruana en las Cortes, y si bien existe un cierto consenso sobre el papel poco relevante de los diputados peruanos en el arco parlamentario doceañista, se conoce menos la trascendencia de las elecciones y de los dictados constitucionales en los dominios coloniales andinos o la actuación de los diputados en defensa de sus provincias. Nuestra propuesta busca aportar una reflexión sobre el eco de lo que Paniagua dio en llamar los orígenes del régimen representativo peruano (Paniagua, 2003) durante la etapa abierta por el virrey La Serna al trasladar la capital al Cuzco a finales de 1821, que se finiquitaría con el retorno al absolutismo a principios de 1824. En ese período, en las provincias de Arequipa, Cuzco, Huamanga, Huancavelica, Puno y Tarma, que aún seguían bajo el dominio español, se aplicó la Constitución de 1812 y las sucesivas leyes y decretos de Cortes emitidos hasta al menos mediados de 1822. Posteriormente, el bloqueo naval impidió que en el Perú se conociera y se implementara la política de la fase exaltada del Trienio Liberal. El trabajo trata de rescatar lo que podría considerarse en cierto sentido el eslabón perdido del segundo liberalismo hispano, una coyuntura que coincidió en el tiempo con el gobierno del general San Martín en el Perú independiente y con el período en que el Congreso Constituyente debatiría y promulgaría la Constitución de 1823. En las siguientes páginas abordamos el proceso de elección de diputados a Cortes, lo que nos servirá para reconstruir tanto su dinámica como la prosopografía de los electores de partido y de los diputados electos.
La música en España a principios de siglo
Authors: Meza Luis Antonio
Published: May 2023

Debo empezar manifestando que, quizá, el título de esta intervención no parezca muy acorde con el rubro general de la convocatoria. Sin embargo, indico la circunstancia de que todos los autores que voy a mencionar, aunque nacidos en el siglo XIX, empezaron a destacar como compositores a fines de esa centuria y sus obras se divulgaron con mayor alcance y eficacia a partir de los albores de la actual. Así, pues, de lo que se trata es de un vistazo somero -no puede ser de otra manera- en tomo de los más importantes compositores ibéricos, en el vasto abanico que se abre de Francisco Asenjo Barbieri a Joaquín Turina. Entrando en materia, no deja de ser una coincidencia feliz y oportuna que, al lado de esa pléyade de intelectuales y literatos de primera magnitud que floreció en España prácticamente en el umbral del siglo XX, coexistiera un número apreciable de músicos talentosos, así como de pintores y dramaturgos. Pese a que ellos no alcanzaron la magnitud que sí logró el pensamiento peninsular, fueron lo bastante destacados como para que el arte, en sus varias expresiones, tuviera también una presencia notable que no desmerece al ser evocada en forma paralela a la generación que contó en sus filas a portentos de sabiduría y humanismo, como Unamuno, Azorín, Maeztu, Valle lnclán, Machado, Benavente, entre otros.
Reflexiones desde el psicoanálisis a los retos ambientales de hoy. A propósito del libro "Desafíos y perspectivas de la situación ambiental en el Perú"
Authors: Hernández Camarero Max
Published: May 2023

A propósito del libro Desafíos y perspectivas de la situación ambiental en el Perú: en el marco de la conmemoración de los 200 años de vida republicana, Augusto Castro y María Isabel Merino Gómez (editores), publicado por el INTE-PUCP, el artículo presenta los aportes de diversos autores que, desde el punto de vista social y psicoanalítico abordan los desafíos del cambio climático. Retomando las palabras de Sally Weintrobe, afrontar el cambio climático, no es un problema técnico o científico, es un problema humano y para abordarlo es necesario tomar en cuenta las variables psicológicas individuales y comunitarias.
Investigation of Antibiotics Residues in Imported and Locally Produced Red Meat in Muscat, Sultanate of Oman
Authors: Al-Kindi Sumaiya , Ahuja Alka , Almaimani Razna , Al-Mamari Siham Khamis , Al-Balushi Mohammed
Published: May 2023

Background: Antibiotics are heavily used for animal treatment, growth enhancer and protection from disease. The residues of antibiotics are related to antibiotic resistance which is the biggest threats to global health, food security and development today. The aim of this study was to investigate the presence of antibiotic residues in available red meat in the Sultanate of Oman. Methods: The extraction was done using QuEChERS method by Aglient and 11 standards were used. The extract was analyzed using The Aglient 6460 LC-MS/MS. Result: The results showed that investigated Omani goat muscle and liver were free of antibiotics as latter they used as blank sample. All investigated Somali goat samples didn’t contain Tetracycline, Amoxicillin, Ceftiofur, Oxacillin, Deoxytetracline, Tylosin and Phenoxymethylpenicillin. Only two samples had Tilmicosin with value of 18-32.2 µl/kg which was that was lower than maxiumam residual limit (MRL). Around 48% of total somali goat samples contained Oxytetracycline (OXY) and Chlorotetracycline (CTC) with value lower than MRL. However, two samples had values of CTC and OXY exceeding the MRL. Ciprofloxacin and Enrofloxacine were detected in 9 samples exceeding the MRL. The finding of this study showed unsafe food source supply to Oman as detection of antibiotic residues in meat.
Penyelesaian Sistem Persamaan Hukum Laju Reaksi dengan Metode Transformasi Differensial
Authors: Maftuhah Siti , Widayani Heni , Kusumastuti Ari
Published: May 2023

This research is focused on solving the rate law equation by using the differential transformation method. The rate law equation describes the chemical reaction problem from the concentration of a reactant that produces a product. The differential transformation method is a semi-analytic numerical method that can provide approximate solutions in the form of a series because the method is obtained from the expansion of the Taylor series expansion. With the help of Maple software, a comparison of the solution plots of y_1 (t),y_2  (t) and y_3 (t), can be observed that the difference in computational results between the Runge-kutta method and the differential transformation depends on the order of k. The curve of the differential transformation method is getting closer to the curve of the Runge-Kutta method at a certain value of k for each y_1 (t),y_2  (t) and y_3 (t). The conclusion of this research is that the application of the differential transformation method has been successfully carried out in the case of a system of ordinary differential equations. For further research, the researcher suggests that the next research applies the method of differential transformation in cases and initial values that are more varied.
Perbandingan Uji Akurasi Fuzzy Time Series Model Cheng Dan Lee Dalam Memprediksi Perkembangan Harga Cabai Rawit
Authors: Ismiarti Dewi , Nafisah Jami'atu Sholichati , Alisah Evawati , Sujarwo Imam
Published: May 2023

Fuzzy Time Series is a method used to predict data. Fuzzy Time Series is a development of time series analysis, where Fuzzy Time Series uses the concept of fuzzy sets as the basis for its calculations. In addition, Fuzzy Time Series has various methods such as Cheng and Lee Fuzzy Time Series. In this study, Fuzzy Time Series is used to predict data on the price development of cayenne pepper in Indonesia. By using these two methods, an analysis of the level of accuracy is then carried out using several methods. So that the results obtained in this study are the MAE value of the Cheng method 669,162 and the Lee method 502,285, the MSE value of the Cheng method 1.261.393 and the Lee method 699.030.1, the MPE value of the Cheng method 0,01% and the Lee method -0,02%, and The MAPE value of the Cheng method is 1,24% and the Lee method is 0.92%. The Lee method has a smaller error value than the Cheng method, so that the Lee method is declared to be better than the Cheng method.
Comunicação e memória em textos de coletivos de teatro feminista no Brasil
Authors: Heller Barbara , Garcia Paula
Published: May 2023

Apesar de os movimentos feministas terem se iniciado há mais de cem anos no Brasil, ainda são poucos os grupos brasileiros que desenvolvem dramaturgia escrita por e para mulheres, ainda que se considere o teatro amador. Apresentamos neste artigo a análise de dois textos teatrais (ou roteiros), ainda inéditos: Boneca de pano, do coletivo de teatro catarinense (Em) Companhia de Mulheres, e Entre Nós: buzinas, chicotes e ácidos, do coletivo cearense Arremate de Teatro. Temos como objetivo compreender, ao compararmos essas duas narrativas teatrais, semelhanças e diferenças dos temas em pauta, considerando seus locais de produção, bem como suas origens. Partimos da hipótese de que narrativas teatrais redigidas por coletivos que se assumem feministas funcionam como um espaço autorizado de fala das brasileiras, de identificação e de ruptura de comportamentos herdados da cultura patriarcal. Confirmamos, a partir dos suportes teóricos sobre teatro, análise do discurso, estudos culturais, de gênero e memória social, que os dois textos em tela se apresentam como formas igualmente potentes de catarse, sensibilização e resistência à domesticação e à opressão a que as mulheres ainda são submetidas.
Cotas Raciais: caminhos abertos entre o “facão” e o “bisturi”
Authors: Silva Vera Regina Rodrigues da
Published: May 2023

In the early 2000s, the debates and clashes over the adoption of affirmative actions, especially through the reservation of vacancies for the black population, the so-called racial quotas, strained the academic scenario. In this article, I use the memory of my academic trajectory from student to university professor during the process of discussion and implementation of racial quotas in Brazil to highlight facts and debates on the topic in focus. In the period between 2000-2012, I will name it as the open path “to the machete” in favor of racial quotas, in which the intensification and polarization contrary to the discussion were felt, as well as the confrontation with the adverse context. From 2012 to the present, I will name it the “scalpel” moment in which the affirmative action policy has legal support and effectiveness in Brazilian society, but it is still fought by its detractors.
User Technology Readiness and Acceptance of Mobile Human Resources Information Application
Authors: Mawaddah Nia Kurnia , Retnowardhani Astari
Published: May 2023

The Mobile Human Resource Application was developed to provide convenience for users. However, in the implementation phase, they have not been used by all users. There are several reasons users do not use the application, namely, employees often forget because they are not ready to use new applications, employees often fail to absent because there are some bugs at the beginning of implementation where the support team is not ready to help users and the employees’ insecurity when making a presentation using the face and location. The purpose of this study is to conduct empirical testing of the factors that influence the readiness and acceptance of users of the Mobile Human Resources Application. The Technology Readiness and Acceptance Model (TRAM) integrates technology readiness with technology acceptance into one model. TRAM is used to determine the effect of technology readiness on acceptance of the perceived ease of use factor and perceived usefulness will affect the intention to use. The result of the study showed that the Innovativeness and Perceived Ease of Use significantly influenced user technology readiness and acceptance of mobile human resources information application. Innovativeness dimensions of technology readiness have positive and significant effects on perceived ease of use. Perceived ease of use dimensions of technology acceptance has positive and significant effects on perceived usefulness and intention to use Mobile Human Resources.
Recent progress in targeting the sialylated glycan-SIGLEC axis in cancer immunotherapy
Authors: Yu Yingyan , Peng Wenjie
Published: May 2023

Malignant tumors are complex structures composed of cancer cells and tumor microenvironmental cells. In this complex structure, cells cross-talk and interact, thus jointly promoting cancer development and metastasis. Recently, immunoregulatory molecule-based cancer immunotherapy has greatly improved treatment efficacy for solid cancers, thus enabling some patients to achieve persistent responses or cure. However, owing to the development of drug-resistance and the low response rate, immunotherapy against the available targets PD-1/PD-L1 or CTLA-4 has limited benefits. Although combination therapies have been proposed to enhance the response rate, severe adverse effects are observed. Thus, alternative immune checkpoints must be identified. The SIGLECs are a family of immunoregulatory receptors (known as glyco-immune checkpoints) discovered in recent years. This review systematically describes the molecular characteristics of the SIGLECs, and discusses recent progress in areas including synthetic ligands, monoclonal antibody inhibitors, and Chimeric antigen receptor T (CAR-T) cells, with a focus on available strategies for blocking the sialylated glycan-SIGLEC axis. Targeting glyco-immune checkpoints can expand the scope of immune checkpoints and provide multiple options for new drug development.
Nova generacija klimatskih aktivista?
Authors: Puđak Jelena , Klasnić Ksenija , Trako Poljak Tijana
Published: May 2023

U radu donosimo rezultate empirijskog istraživanja kojem je cilj bio ispitati‎ oblike podrške i sudjelovanja hrvatskih srednjoškolaca u prosvjedima za klimu ‎“School Strike for Climate Hrvatska”, kao i neke individualne i kontekstualne‎ determinante njihovih stavova i sudjelovanja. Istraživanje je provedeno‎ metodom online ankete 2020. i 2021. godine na prigodnom uzorku završnih ‎razreda hrvatskih srednjih škola (N=534). Rezultati pokazuju da je oko 8% ‎učenika bilo na neki način aktivno povezano s pokretom. Pomoću analize‎ glavnih komponenata utvrđena su tri tipa stavova učenika prema prosvjedu ‎i prosvjednicima, nazvana: “borbeni stavovi za zaštitu okoliša”, “univerzalno aktivistički ‎stavovi” i “podržavateljski stavovi”. Dodatno, multivarijatnom ‎analizom testiran je efekt socio-demografskih obilježja zajedno s konstruktima‎ percepcije kolektivne učinkovitosti, ekološke zabrinutosti, ekološkog ‎svjetonazora te stavova o Greti Thunberg kao inicijatorici globalnog pokreta ‎Fridays for Future na utvrđene stavovske strukture. Pokazalo se da su uključene‎ determinante statistički značajni prediktori, ali ne na isti način za svaku‎od tri stavovske dimenzije.‎
Mathematica Montisnigri journal is 30
Authors: Pavićević Žarkop , Mazhukin Vladimir Ivanovich
Published: May 2023

The article is dedicated to the 30th anniversary of the publication of the journal Mathematica Montisnigri. The founders of the journal are the Association of Mathematicians and Physicists of Montenegro and the Faculty of Sciences and Mathematics of University of Montenegro, Keldysh Institute of Applied Mathematics of the Russian Academy of Sciences (KIAM). The chief editors of the journal are prof. Žarkop Pavićević (University of Montenegro) and prof. V.I. Mazhukin (KIAM). The first issue of the magazine was published in May 1993. The history of the organization of the institution and the publication of the journal is traced. The role of the rector of Lomonosov Moscow State University аcademician V.A. Sadovnichy and prof. of the Faculty of Mechanics and Mathematics of Lomonosov Moscow State University V.I. Gavrilov in creating the journal. The development of the journal and the role of mathematicians of the University of Montenegro and mathematicians of the Keldysh Institute of Applied Mathematics of RAS in this process.
On some new boundary properties of normal harmonic functions
Authors: Berberyan Samvel , Dallakyan Rubik
Published: May 2023

In this paper, some boundary properties of normal harmonic functions defined in the unit circle D are investigated. Similar results for meromorphic and holomorphic functions defined in D were considered in the works of Professor V. I. Gavrilov and other authors. Next, we consider the question of the existence of irregular points for harmonic functions
Cubic intuitionistic structures of a semigroup in KU-algebra
Authors: Davvaz Bijan , Kareem Fatema F. , Awad Wisam K.
Published: May 2023

An intuitionistic fuzzy set was exhibited by Atanassov in 1986 as a generalization of the fuzzy set. So, we introduce cubic intuitionistic structures on a KU-semigroup as a generalization of the fuzzy set of a KU-semigroup. A cubic intuitionistic k-ideal and some related properties are introduced. Also, a few characterizations of a cubic intuitionistic k-ideal are discussed and new cubic intuitionistic fuzzy sets in a KU-semigroup are defined.
Development of an Integrated System for Molecular-Genetic Identification of Yersinia pestis Strains
Authors: Nikiforov K. A. , Oglodin E. G. , Makashova M. A. , Balykova A. N. , Utkin D. V. , Kukleva L. M. , Eroshenko G. A. , Kutyrev V. V.
Published: May 2023

The paper describes a developed comprehensive system for molecular-genetic identification of Yersinia pestis strains according to their appurtenance to certain subspecies, biovars, phylo-geographic populations, using realtime PCR (RT-PCR), allele-specific RT-PCR, and multiplex PCR with hybridization fluorescent registration of results on a solid substrate. Application of this system makes it possible to establish the appurtenance of Y. pestis strains to the following phylogenetic branches: 0.ANT1, 0.ANT2, 0.ANT3, 0.ANT5, 3.ANT, 4.ANT of antique biovar of the main subspecies; 2.MED0, 2.MED1, 2.MED2, 2.MED3, 2.MED4 of medieval biovar of the main subspecies; 1.IN1, 1.IN2, 1.IN3 of intermedium biovar of the main subspecies; 1.ORI1, 1.ORI2, 1.ORI3 of oriental biovar of the main subspecies; 0.PE3 (angolica subspecies), 0.PE7 (tibetica subspecies) and 0.PE10 (qinghaica subspecies). The first stage of the studies within the frames of the developed system is indication of plague agent using registered diagnostic drugs. The second stage is the determination of belonging to individual subspecies through RT-PCR or by the method of multiplex PCR system with hybridization-fluorescent registration of results on a solid substrate, which also allows for establishing to which biovars of the main subspecies and the main phylogenetic lines of the ancient biovar the strains belong. The third stage is the identification of strain appurtenance to phylogenetic branches by the AS-RT-PCR method. The designed complex system for molecular-genetic identification of Y. pestis strains can be applied at the regional and federal levels of the laboratory network of the Russian Federation for diagnostics of infectious diseases. Its use will considerably facilitate and increase the efficiency of intraspecific differentiation of Y. pestis strains within the framework of the epidemiological investigation of outbreaks or importation of strains of plague pathogen into the territory of the Russian Federation or during the certification of strains in collection activities.
Typing of Uncultured Isolates of Coxiella burnetii and Coxiella-Like Microorganisms Associated with Ticks Using 16S rRNA Gene Nucleotide Sequence Analysis
Authors: Panferova Yu. A. , Tokarevich N. K. , Blinova O. V. , Nafeev A. A. , Sibaeva E. I.
Published: May 2023

The causative agent of Q fever, the intracellular pathogen Coxiella burnetii, is found almost worldwide; many types of blood-sucking ticks that are dangerous to animals and humans are involved in the circulation of the pathogen. Using molecular-genetic methods, closely related species of microorganisms of the genus Coxiella sp. have been discovered, some of which are endo-symbionts of ticks, and some can survive in the human body, causing an infectious process. The existence of species whose genes are similar in nucleotide sequence to those of C. burnetii makes it difficult to diagnose the pathogen in arthropod vectors. The aim of this work was to consider the use of PCR and sequencing of an extended 16S rRNA gene fragment for molecular diagnostics and differentiation of C. burnetii from Coxiella-like microorganisms. Materials and methods. Individual samples of blood-sucking ticks were examined to detect bacteria of the genus Coxiella sp. applying standard PCR. For positive samples, an extended fragment of the 16S rRNA gene was obtained and examined by sequencing and multiple alignment with homologous sequences. Results and discussion. Of the 96 examined ticks collected in the Ulyanovsk Region, one was positive for the presence of C. burnetii DNA and one – for the presence of Coxiella sp. The greatest similarity for the C. burnetii isolate was noted in comparison with Western European strains, for the Coxiella-like microorganism - with closely related bacteria from ticks of the same species. Unique polymorphisms for the detected microorganisms were identified. It has been established that genus-specific primers to the 16S rRNA gene fragment are able to amplify not only bacteria of the genus Coxiella sp., but also genetically distant species. Analysis of the sequence of the extended 16S rRNA gene fragment makes it possible to differentiate C. burnetii from Coxiella-like microorganisms; some gene polymorphisms appear to have arisen through microevolution in different geographic regions. In the European part of the Russian Federation, Coxiella-like bacteria have been uncovered for the first time.
The Risk of Nerve Injury in Pediatric Forearm Fractures
Authors: Zilliacus Kaj , Nietosvaara Yrjänä , Helenius Ilkka , Laaksonen Topi , Ahonen Matti , Grahn Petra
Published: May 2023

Update

This article was updated on July 19, 2023, because of a previous error, which was discovered after the preliminary version of the article was posted online. On page 1080, in the last sentence of the Results section of the Abstract, the text that had read “0.05% (4 of 777)” now reads “0.5% (4 of 777).”

Background:

The risk of fracture-related nerve injury associated with forearm fractures in children is unknown. The purposes of the present study were to calculate the risk of fracture-related nerve injury and to report the institutional rate of complications of surgical treatment of pediatric forearm fractures.

Methods:

Four thousand, eight hundred and sixty-eight forearm fractures (ICD-10 codes S52.0 to S52.7) that had been treated in our tertiary level pediatric hospital between 2014 and 2021 were identified in our institutional fracture registry. Of these, 3,029 fractures occurred in boys and 53 were open fractures. Sex, age at injury, trauma mechanism and energy, fracture type, treatment method, and cause and type of nerve injury were assessed in 43 patients with 44 registered nerve injuries. Patients with nerve injuries were reevaluated to calculate the recovery time. Univariable and multivariable regression analyses were performed to determine the risk of nerve injury.

Results:

The risk of a fracture-related nerve injury was 0.7% (33 of 4,868). Only 2 injuries were permanent; thus, the risk of permanent nerve injury associated with a forearm fracture was 0.04% (2 of 4,868). The ulnar nerve was affected in 19 cases; the median nerve, in 8; and the radial nerve, in 7. In cases of open fracture, the risk of nerve injury was 17% (9 of 53). Open fractures had an OR of 33.73 (95% CI, 14.97 to 70.68) on univariate analysis and an OR of 10.73 (95% CI 4.50 to 24.22) on multivariate analysis with adjustment for female sex and both-bone diaphyseal fracture. Both-bone diaphyseal fracture (ICD-10 code S52.4) had an OR of 9.01 (95% CI, 4.86 to 17.37) on univariate analysis and an OR of 9.98 (95% CI 5.32 to 19.47) on multivariate analysis with adjustment for age and female sex. Overall, 777 fractures were internally fixed. The risk of nerve injury as a complication of internal fixation was 1.3% (10 of 777). Four of these iatrogenic injuries (including 2 involving the median nerve, 1 involving the ulnar nerve, and 1 involving the radial nerve) were permanent; thus, the risk of permanent nerve injury as a complication of internal fixation was 0.5% (4 of 777).

Conclusions:

Nerve injury following a pediatric forearm fracture is rare and has an excellent potential for spontaneous recovery. In the present study, all of the permanent nerve injuries occurred in association with open fractures or as a complication of internal fixation.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.