bluuebunny/crossref_metadata_2025 huggingface dataset:
From Emissions to Economy: Company Characteristics and Carbon Disclosure in Southeast Asia
Authors: Warokka Ari , Barroso Manuel Monjas , Aqmar Aina Zatil
Published: May 2024

This study investigates the relationship between company characteristics, carbon emission disclosure, and economic consequences in five ASEAN countries. By utilizing data from 2008 to 2017, the research focuses on non-financial companies, selected due to their prominence as the highest carbon-emitting nations in the ASEAN region. Results reveal that profitability positively influences carbon emission disclosure, while leverage exhibits no significant effect. Additionally, company size positively impacts carbon emission disclosure, whereas sales growth demonstrates a negative effect. Furthermore, carbon emission disclosure positively affects economic consequence variables. These findings offer practical implications for practitioners and investors, emphasizing the importance of considering carbon emission disclosure in investment decisions.
СПЕЦІАЛЬНІ ПРИНЦИПИ ТРАНСФОРМАЦІЇ УПРАВЛІНСЬКИХ ПРОЦЕСІВ ПІДПРИЄМСТВ У КОНТЕКСТІ ПОВОЄННОГО ЗАБЕЗПЕЧЕННЯ ЕКОНОМІЧНОЇ БЕЗПЕКИ БІЗНЕСУ
Authors: Моторнюк Уляна , Йосипчук Володимир , Касперський Павло
Published: May 2024

У статті виокремлено й охарактеризовано спеціальні принципи трансформації управлінських процесів підприємств у контексті повоєнного забезпечення економічної безпеки бізнесу. До переліку таких принципів віднесено: принцип орієнтації на кінцевого споживача, принцип стратегічної орієнтації змін, принцип поєднання економічних та соціальних аспектів трансформації, принцип постійного вдосконалення, принцип врахування інтересів стейкхолдерів та принцип прогнозування кон’юнктури ринку. Знання і розуміння зазначених принципів дає змогу забезпечити ефективність процесів трансформації управлінських процесів та спрямувати їх у потрібне русло. Крім того, створюються можливості і для розвитку суб’єктів господарювання та підвищення їхньої конкурентоспроможності у повоєнний період відновлення економіки. Усе це позитивно вплине і на забезпечення економічної безпеки підприємств.
Рівень стоматологічної освіти в студентів різних факультетів університету м. Ужгорода
Authors: Мельник Володимир Семенович , Халак Роман Олегович , Кий Валентина Михайлівна , Онисько Олександра Михайлівна
Published: May 2024

Дані, отримані в результаті проведеного анкетування студентів, дозволили визначити рівень знань про гігієну ротової порожнини. Мета дослідження: провести порівняльну оцінку знань про методи профілактики захворювань ротової порожнини в студентів різних факультетів університету м. Ужгорода. Матеріали та методи. На базі університетської стоматологічної поліклініки Ужгородського національного університету проведено анкетування та стоматологічне обстеження студентів 1-2 курсів стоматологічного та фізичного факультетів Ужгородського національного університету. Загальна кількість обстежених – 220 осіб. Середній вік респондентів становив 19.0 ± 1,2 років. Анкета містила запитання щодо основ правильного харчування: кратності прийому їжі на день, вживання солодких продуктів, напоїв, частоти вживання твердих овочів і фруктів. А також були запитання, що стосуються основних правил користування зубною щіткою (ступеня жорсткості щетини, часу, через який проводиться її заміна), визначення рівня знань основних гігієнічних навичок чищення зубів, режиму та часу. Результати. За даними анкетування, більшість опитаних прислухаються до порад стоматолога та гігієніста, чистять зуби двічі на день, змінюють зубну щітку 3-4 рази на рік та використовують зубну щітку середньої жорсткості (студенти стоматологічного факультету – 92,8; 69,6; 38,4 та 88%, фізичного факультету – 72; 56,8; 40 та 84% відповідно). Користуються додатковими засобами гігієни 52% респондентів-фізиків, використовують додаткові засоби гігієни – 43,2% опитаних студентів-стоматологів. За даними анкетування з'ясувалося, що більшість респондентів чистять зуби двічі на день (студенти-стоматологи – 73,6%, фізики – 56,8%), один раз на день чистять зуби 24% опитаних стоматологів та 40% фізиків, три рази на день чистять зуби 2,4% студентів-стоматологів та 3,2% фізиків. Також 38,4% студентів-стоматологів чистять зуби після сніданку та перед сном, 25,2% – перед сніданком і перед сном, 19,2% – перед сніданком, 6% – після сніданку, 4,8% – три рази на день, 3,2% – перед і після сніданку і 3,2% – тільки перед сном. Серед студентів-фізиків 36% чистять зуби після сніданку та перед сном, 28% – перед сніданком та перед сном, 20% – перед сніданком, 8% – після сніданку, 4% – перед сном та 4% – щоразу після їжі. Більшість опитаних стоматологів (68%) приділяють чищенню зубів 3-4 хвилини, 26% – 1-2 хвилини і 6% – 5-6 хвилин. Більшість респондентів-фізиків (60%) чистять зуби 1-2 хвилини, 36% – 3-4 хвилини і 4% – 5-6 хвилин. Висновки. Очевидно, що рівень стоматологічного здоров'я безпосередньо залежить від рівня стоматологічної освіти. Існує необхідність більшої поінформованості населення за рахунок засобів освіти (книг, брошур, плакатів, журналів, реклами), проведення санітарно-просвітницької роботи та уроків здоров'я в школах.
Optimizing Time Performance in Implementing Green Building Concepts on High-Rise Residential by using M-Pert
Authors: Detty Kussumardianadewi Bernadette , Eddy Husin Albert , Septia Prawina Riza
Published: May 2024

Climate change is a threat and crisis that is sweeping the world today, therefore the target towards Net Zero Emissions (NZE) by 2060 must be an obligation of all countries. The greenhouse effect, global warming, destruction of the ozone layer, destruction of forests, uncontrolled use of CFCs, and industrial disposal are factors that cause climate change. The consequences of climate change are dire, resulting in droughts, water scarcity, land fires, rising sea levels, flash floods, melting polar ice caps, storms, and biodiversity decline. Green buildings (GB) are important in saving energy, water, and other resources by meeting technical construction standards and applying green building principles with measurable performance. It is expected to reduce carbon emissions or greenhouse gases. From the results of research with the application of M-PERT, it is proven to be able to provide an accuracy of 98.93% implementation time in high-rise residential buildings
Analysis of Optimum Asphalt Content of Lasbutag Mixture (Buton Aggregate Asphalt Coating) Modified by Waste Oil and Diesel as Modifier
Authors: Wintari Ni  Kadek , Desi Natsar , Gusty Sri
Published: May 2024

Asbuton, a natural asphalt source on Buton Island in Southeast Sulawesi, is one of Indonesia's potential sources of natural wealth. As a road pavement material, LASBUTAG still has many weaknesses. This is especially true for cold LASBUTAG mixtures, which are only suitable for highways with light traffic. To mix Asbuton in cold conditions, a modifier is needed, the data of which is rare on the market, so other alternatives need to be considered as a modifier. In this research, we will try to use a mixture of waste oil and diesel as a modifier. The use of waste oil in this research is by looking at the development of the volume of waste oil. which continues to increase along with the increase in the number of motorized vehicles and motorized machines. The spread of oil waste is very widespread from big cities to rural areas throughout Indonesia. Waste from lubricating oil is included in B3 waste which needs special treatment in its processing. The aim of this research is to analyze the optimum asphalt content of cold Lasbutag mixtures with modifier materials from waste oil and diesel. From the results of this research, the Optimum Asphalt Content (KAO) in the Lasbutag Wearing Course (WC) mixture was 6.30% of the total mixture weight. Based on regression analysis, asphalt content can produce stability of 704.464 kg, flow of 3.078 mm, Vim of 4.467%, VMA of 17.077% and IKS of 78.763%. These values have met the requirements set out in the 2006 Special Lasbutag specifications.
Environmental Design for the Reconstruction of PT X Ex-Mine Land Reclamation, Bombana Regency, Southeast Sulawesi Province
Authors: Haslinda Haslinda , Indrayani Poppy , Chaerul Muhammad
Published: May 2024

The study area is located in the IUP of PT X, which covers an area of ± 1,210 ha. Administratively located in Bombana Regency, Southeast Sulawesi Province. Spatial data analysis in mapping the potential success rate of reclamation and environmental design is carried out based on geological criteria and remote sensing so that the impact of risks in the mining industry can be minimized. This study aims to map the potential success rate of post-mining land reclamation and environmental design in the study area based on spatial analysis with the Analytical Hierarchy Process (AHP) method. The geological criteria used in this study are lithological units, seismicity, hydrology (catchment area), vegetation density distribution, and hydrothermal alteration (iron oxide alteration and clay minerals). The data used in this study are the Kolaka sheet regional geologic map, DEM SRTM, Landsat 8 imagery, and company reports (lithology, reclaimed land openings). The data were analyzed to produce evidence maps of lithology, ranginess, catchment area, and vegetation density distribution using the NDVI technique and hydrothermal alteration using the band ratio technique, then spatial analysis was carried out using the AHP method. The result of this research is a map illustrating the potential success rate of reclamation and environmental design in the study area which is divided into 3 classes, namely: high potential area of 407.52 Ha (36.68%), medium potential area of 360.81 Ha (32.48%), and low potential area of 342.54 Ha (30.84%) of the total area. Based on the validation test of the reclaimed land opening area of 28.63 Ha that corresponds to the area with the result of a high potential success rate of about 89% of the total validation land opening area the results of this modeling are statistically acceptable.
Violence against Blue-Eyed Women in the Novel Nyutrayu by Joko Gesang Santoso
Authors: Midle Line Krismonsari  , Wiyatmi
Published: May 2024

This research aims to determine the form of violence experienced by the blue-eyed female character in the novel Nyutrayu by Joko Gesang Santoso. Researchers use feminist literary criticism theory. The data source for this research was obtained from a quote from the novel Nyutrayu, which describes the violence experienced by the blue-eyed female character. The data collection process uses data collection techniques through literature study, reading techniques, and note-taking techniques. The literature study technique is carried out by collecting, reading and studying books on feminist literary criticism theory; the reading technique is carried out repeatedly in the novel Nyutrayu, and the note-taking technique is to record quotes that show data in the form of violence experienced by the blue-eyed female character. Next, data validity techniques are carried out using validity tests and reliability tests. The validity test is carried out by interpreting the data based on the problem formulation and in accordance with feminist literary criticism. Meanwhile, the reliability test was carried out by repeatedly reading the novel Nyutrayu by Joko Gesang Santoso and discussing it with colleagues. The data analysis technique is carried out in three stages. First is data reduction, namely data collected and grouped according to the problem formulation. The second is data presentation, namely grouping data into data cards. Third, conclusions and verification are drawn, namely the final conclusion of the data, which is temporary and can change if evidence is found to support the data collection stage. The results of the research show that 1) the physical violence experienced by the blue-eyed female character was in the form of being killed by a group of men, being hit with a broom handle, and being injured by village youths using a machete. 2) psychological violence experienced by the blue-eyed female character in the form of being stalked by villagers, being accused of being a witch, and being threatened with death. And 3) sexual violence experienced by the blue-eyed female character in the form of sexual harassment and rape.
A Systematic Analysis of Kahoot's Potential as a Tool for Improving EFL Instruction
Authors: Hadi Priaditya Tri , Biladt Septananda Roseandree Biladt Septananda Roseandree , Fatoni Zidanu , Hendriwanto  , Mumpuni Rahayu Yuna
Published: May 2024

This research provides a meta-analysis of an issue regarding the effectiveness of using Kahoot in English language learning environments from 2020 to 2024, focusing on the yearly publication rate, participant demographics, challenges, and benefits. It delves into the impact of technology integration and gamification on student learning outcomes, emphasizing the importance of motivation and engagement in educational settings. The systematic review explores some papers about Kahoot! in improving learning results in English for Foreign Language classes. It highlights the benefits of gamification in education, emphasizing Kahoot's ability to engage students' motivation and academic performance. This study also found some gaps in using Kahoot for English language learning among EFL students, including technology, competition, time management, classroom management, content creation, cultural relevance, and pedagogy. However, it shows several benefits, such as improved learning interest and process, better subject perception, higher class participation, and a more lively classroom state. Following the results, the researcher hopes this paper could give the impression that technology can provide great tools for improving English language learning, either for EFL learners or EFL teachers.
Strategi pendidikan kesehatan dan penurunan stigma TB di masyarakat: A systematic review
Authors: Marissa Anggraini , Rekawati Etty , Nursasi Astuti
Published: May 2024

Background: Tuberculosis stigma is a challenge in TB management for health care in the community. According to previous research, health education can significantly improve knowledge about TB and reduce public stigma against it.
Purpose: To identify how interventions can improve public knowledge about tuberculosis and decrease the stigma people have about TB.
Method: Systematic review academic articles were searched through online databases from 2018 to 2022, and 6 articles were obtained for analysis.
Results: Health education was provided to the community with a variety of approaches, including structured education, empowerment of the community, support and motivation from the community cadres, a gender approach, and workshop/compliance for service provider agency officials.
Conclusion: The provision of structured health education and the approach characterized by local communities proved effective in increasing knowledge about TB and reducing the growing stigma in the community towards TB patients.
 
Keywords: Health Education; Social Stigma; Tuberculosis (TB).
 
Pendahuluan: Stigma terhadap TB adalah tantangan dalam pengelolaan TB bagi tenaga kesehatan di masyarakat. Dari penelitian terdahulu, secara signifikan pendidikan kesehatan dapat meningkatkan pengetahuan mengenai TB dan menurunkan stigma masyarakat terhadap TB.
Tujuan: Untuk mengidentifikasi intervensi yang dapat meningkatkan pengetahuan masyarakat mengenai TB dan menurunkan stigma TB.
Metode: Systematic review menggunakan penelusuran artikel akademik melalui online database dari tahun 2018-2022 dan didapatkan 6 artikel untuk dianalisis.
Hasil: Pendidikan kesehatan yang diberikan kepada masyarakat dengan berbagai strategi pendekatan antara lain,  edukasi terstruktur, pemberdayaan masyarakat, dukungan dan motivasi dari kader masyarakat, pendekatan gender, dan pelatihan bagi petugas instansi pemberi layanan. 
Simpulan: Pemberian pendidikan kesehatan terstruktur dan pendekatan sesuai dengan kondisi masyarakat setempat terbukti efektif dalam peningkatan pengetahuan mengenai TB dan menurunkan stigma yang berkembang di masyarakat terhadap penderita TB.
 
Kata Kunci: Pendidikan Kesehatan; Stigma Masyarakat; Tuberkulosis (TB).
Diagnosis of Congenital Diaphragmatic Hernia
Authors: Pegkou A. , Fasoulakis Z. , Tasias K. , Chatziioannou M.I. , Asimakopoulos G. , Theodora M. , Daskalakis G. , Antsaklis P.
Published: May 2024

Background: Congenital Diaphragmatic Hernia (CDH) is a life-threatening condition occurring in newborns, characterized by a defect in the diaphragm that allows abdominal organs to migrate into the thoracic cavity. This report presents a case of CDH, outlining its diagnosis and highlighting the importance of early detection and management. We describe a case of a prenatal diagnosed left-side CDH that underwent karyotype screening with parents chosing termination of pregnancy. This case underscores the critical need for early diagnosis of CDH. In our review, we emphasize the role of prenatal ultrasound and MRI in early detection and evaluation of CDH, the importance of delivery in a specialized center capable of providing high-level neonatal care, and the need for ongoing research to improve prognosis and manage long-term complications associated with CDH.
Inventory, and Dissemination of Citrus Fungal Diseases in Benin
Authors: Toessi Goudjo H. , Amari Elisée G. D. L. , Sikirou Rachidatou , Yéo Yéfoungnigui S. , Adanvé Jean-Fabrice
Published: May 2024

Fungal diseases are a major constraint for the intensification of citrus production in Benin. The aim of this study was to identify the main citrus fungal diseases and to assess their distribution, prevalence, and severity). A total of 315 orchards were surveyed in the four agro-ecological zones (AEZ V, VI, VII, and VIII) where citrus is produced in Benin. During the surveys, samples of diseased fruits were collected for isolation in the laboratory. The results revealed four main fungal diseases including black spot caused by Phyllosticta sp., anthracnose caused by Colletotrichum sp., brown rot disease caused by Curvularia sp., and fruit rot caused by Fusarium sp. Among these diseases, black spot is the most distributed with 76.69% infected plants as compared to anthracnose, brown rot disease and fruit rot which infected 32.4%, 6.3% and 1.9% of plants respectively. The diseases severity was 2.88, 1.46, 1.08 and 0.60 for black spot, anthracnose, brown rot and fruit rot respectively. Of the three cultivated varieties, Pineapple and Valencia were susceptible to the four diseases while the variety Tangelo was less susceptible. The highest severity (3.51) was recorded in the AEZ VI and the lowest (0.81) in the AEZ VII. This study showed that citrus tree was susceptible to several diseases in Benin with black spot disease caused by Phyllosticta sp., as the most important. Any effort to increase qualitatively and quantitatively citrus productivity should be based on sustainable management of diseases
Bioactivity of Some Endophytic Fungi from Cameroonian Medicinal Plants against Verticillium albo-atrum, Rhizoctonia carotae and Phytophthora megakarya
Authors: Djeugap Joseph F. , Mbatkam Biamen , Kouam Siméon F. , Nouteka Niky J. , Kuenbou Joachim M. , Teponno Rémy B.
Published: May 2024

Endophytic fungi (EFs) are beneficial microorganisms which grow in living plant tissues without causing any disease to their hosts. Most of them have antifungal properties. EFs of three herbaceous plants namely Lantana camara, Emilia coccinae and Bryophyllum pinnatum were isolated by using potato dextrose agar medium (PDA) and screened for their antifungal activity on the double direct confrontation (DDC) test on PDA. The growth diameter of pathogenic fungi with or without endophyte was measured weekly. Then, fourteen days after the DDC test, fungicidal or fungistatic activity of the EFs was assessed on the pathogens’ growth. Finally, EFs that strongly inhibited pathogens’ growth were submitted to the morphological characterization on PDA, Malt Extract Agar (MEA) and Sabouraud Dextrose Agar (SDA) media at three pH levels (5.2, 7 and 9). Results showed that eight EFs genera are associated with these herbaceous medicinal plants with diverse antifungal activities. EFs that significantly (p 0.05) inhibited the growth of the three pathogenic fungi were: Trichoderma harzianum (66%), Cercospora sp (58%) and Aspergillus sp (49%), 7 days after the DDC test. Endophytes T. harzianum and Cercospora sp were fungicidal on the three pathogens while Aspergillus sp was fungicidal on V. albo-atrum and R. carotae. There was a high morphological variability (colour, texture and pigments produced by EFs on culture media), and variability in their daily growth diameter and sporulation among EFs from one medium to another and from one pH level to another. This study suggests that T. harzianum and Cercospora sp endophytes possess the high antagonistic activity and can be used as an alternative to synthetic chemicals that control plant diseases
PENGARUH PROPILENGLIKOL TERHADAP FORMULASI DAN KARAKTERISTIK FISIK SEDIAAN PATCH EKSTRAK ETANOL DAUN INGGU (Ruta angustifolia L. Pers)
Authors: Hikma Nurul , Yassir Budiman , Khairi Nur , Marwati Marwati , Pattinggi Patricia
Published: May 2024

Ruta angustifolia L.Pers contain essential oil, steroids, flavonoids, tannins, quinones, and saponins compounds which have the potential to act as analgesics. This research aimed to determine the effect of varying propylene glycol concentrations on the physical characteristics of patches using the solvent evaporation method. Patch preparations were made in 3 formulas with variations of propylene glycol, namely F1 (without propylene glycol), F2 (10%), F3 (20%), and F3 (30%), and the patch was evaluated. The results of the physical characteristics obtained were patches with a yellowish green color, typical extract smell, round shape, thin film, smooth, dry, and elastic with a folding resistance of >200 times, thickness ranging from 0.02-0.03 mm, weight uniformity meeting the requirements, namely CV value 5%, %drying loss <9.20%, humidity of each formula <9.79% with a pH of around 7. Thus, it can be concluded that the ethanol extract of inggu leaves influences the uniformity of the weight and thickness of the patch.
PENERAPAN CUSTOMER SATISFACTION INDEX (CSI) DAN ANALISIS GAP PADA KUALITAS PELAYANAN KEFARMASIAN DI APOTEK SEHAT BERSAMA 2 JAKARTA TIMUR
Authors: Brahmono Angga , Susanto Yugo , Widiyanto Rahmat , Erzania Reyfana
Published: May 2024

Health quality assurance is a very important and fundamental approach or effort in providing health services. One form of service quality in the health service sector is pharmaceutical services in pharmacies. Satisfaction is an important part of pharmaceutical services because it is useful for improving medical health service outcomes. The aim of this research is to analyze customer satisfaction and expectations regarding the performance of pharmaceutical services at Apotek Sehat Bersama 2. The methods used in this research are the Customer Satisfaction Index (CSI) method and Gap Analysis. This research method is a survey, namely by distributing questionnaires to pharmacy customers. The sampling technique was carried out by accidental sampling with 188 respondents. The scale used is a Likert scale based on the level of satisfaction and expectations. The research results show that the Customer Satisfaction Index (CSI) value for customer satisfaction level is 82.4%, which is included in the very satisfied criteria. The highest gap value is an indicator that pharmacy staff understand customer complaints, provide drug/health information clearly and easily understood, always provide information on how to use drugs requested by customers, pharmacy staff are always polite and friendly in providing service to customers and pharmacy staff provide information on usage rules. drugs and side effects that may arise as well as the lowest gap value is that the drug requested by the customer is always available.
Perancangan Teknik Kriptografi Block Cipher Berbasis Pola Peta Administrasi Kalimantan Barat Menggunakan Key-Dependent S-Box
Authors: Edo  , Helfi Nasution  , Muhammad Azhar Irwansyah
Published: May 2024

Kriptografi adalah teknik pengamanan informasi yang dilakukan dengan cara mengubah pesan menggunakan suatu metode enkripsi sehingga tidak dapat dibaca secara langsung oleh pihak yang tidak berhak. Block cipher merupakan salah satu algoritma kriptografi yang menggunakan kumpulan bit dengan panjang tetap untuk mengenkripsi pesan. Metode enkripsi kriptografi block cipher pada dasarnya dilakukan dengan cara melakukan pertukaran kode bit pesan sehingga membentuk suatu pesan baru yang tidak dapat dibaca (ciphertext). Penelitian dilakukan dengan tujuan merancang kriptografi block cipher baru yang merepresentasikan ciri khas pola peta administrasi Kalimantan Barat dalam pertukaran kode bitnya. Perancangan kriptografi dilakukan dengan mengacu kepada algoritma kriptografi block cipher Advance Encryption Standard (AES) yang ditetapkan oleh National Institute of Standard and Technology (NIST) sebagai standar pengamanan informasi di dunia. Algoritma kriptografi yang dirancang juga menggunakan substitusi box (S-Box) dinamis yang dibangkitkan dengan kunci sehingga berbeda dengan S-box statis AES. Pengujian terhadap performa algoritma kriptografi menunjukkan hasil yang baik. Hasil pengujian avalance effect mendapatkan nilai rata-rata 50,524%. Simulasi waktu enkripsi per 500 blok data rata-rata membutuhkan waktu 3,514 detik. Analisis serangan brute force menunjukkan waktu yang diperlukan untuk melakukan exhaustive search memerlukan detik atau setara  tahun. Algoritma kriptografi yang dihasilkan dapat bekerja dengan baik dalam 5 mode operasi block cipher yang direkomendasikan oleh NIST, yaitu Electronic Code Book (ECB), Cipher Block Chaining (CBC), Cipher Feedback (CFB), Output Feedback (OFB), dan Counter (CTR). Penelitian juga mengimplementasikan algoritma kriptografi ke dalam sebuah aplikasi surat elektronik berbasis web.
Design Thinking: Pengembangan UI/UX Aplikasi Evaluasi Pembelajaran Mata Kuliah Berbasis Web
Authors: Hafidz Mohammad Al , Herlambang Cahya Pratama Yudha , Maulidya Effendi Pradita
Published: May 2024

Perkembangan teknologi yang begitu cepat menjadikan sumber belajar kini tidak hanya melalui guru saja, melainkan bisa melalui perangkat bergerak, seperti smartphone, tablet, komputer, dan lainnya. Kehadiran aplikasi pendidikan yang terhubung dengan koneksi internet dianggap efektif dalam mendukung proses belajar mengajar. Keberhasilan aplikasi yang dikembangkan di institusi pendidikan tidak lepas dari perancangan sistem yang baik. Universitas Hayam Wuruk Perbanas, salah satu perguruan tinggi di Indonesia saat ini membutuhkan aplikasi berbasis web untuk mengevaluasi pembelajaran mahasiswa. Penelitian ini berjuan untuk mengembangkan perancangan UI/UX pada aplikasi evaluasi pembelajaran pada mata kuliah algoritma dan pemrograman. Metode yang digunakan adalah Design Thinking yang melibatkan lima tahapan, yaitu: empathize, define, ideate, prototype, dan test. Kelima tahapan dari metode design thinking yang dilakukan mampu memetakan strategis bisnis dengan perasaan dan kebutuhan dari pengguna, merumuskan kebutuhan atau masalah dengan jelas, serta menghasilkan sketsa dan prototype aplikasi. Prototype yang dihasilkan juga telah diujikan melalui keterlibatan partisipan dari dosen maupun mahasiswa. Hasil pengujian tersebut menghasilkan prototypeakhir yang dirasa oleh pengguna sesuai dengan kebutuhan, mudah digunakan, dan penguna merasa tampilan antar muka yang menarik dan informatif.
Complaint Analysis of LPG Gas Checking Station
Authors: Hambali Ahmad , Abdullah Ishlahuddin
Published: May 2024

Background: Hydrocarbons are a major source of energy, both for industrial and domestic applications. LPG (Liquefied Petroleum Gas) or LPG is a combustible hydrocarbon gas consisting of a mixture of propane and butane hydrocarbons. LPG is a product obtained from refining crude oil and gas, is an energy source for household cooking, industrial ovens, power plants and as a fuel for vehicles.
Objective: To determine the factors that cause complaints of musculosceletal disorder (MSDs)
Method: Nordic Body Map is used to determine musculosceletal disorder (MSDS) complaints felt by workers. MSDs complaints will be known using questionnaires in the form of several types of MSDs complaints on the human body map. Through this questionnaire with a total of 12 0rang respondents, it can be known the part of the muscle that experienced complaints with the level of complaints ranging from No Pain, Somewhat Pain, Pain and Very Pain. NBM results can estimate the type and level of complaints, fatigue, and  The muscles felt by the workers, by viewing and analyzing body maps taken from filling out the NBM questionnaire ranged from discomfort to extreme pain.
Result: Based on the results of the data that has been processed, it can be seen that the level of complaints that have a risk of injury to the muscles, the left shoulder, right shoulder, and waist and back. The muscle part that has been filled by operator one (1) and operator two (2) where the muscle part scales (2) two (somewhat painful). Then after overcoming the part of the muscle that is at risk of injury, an individual operator is scored, which is done.
Conclusion: there is no significant relationship of knowledge with the use of PPE in oil palm harvest workers, there is a significant relationship with the use of PPE in workers of Pt Agra Budi Gas Utama, There is no significant relationship of comfort with the use of PPE in workers filling Gas Utama at PT. Agra Budi Gas Utama.
Simultaneous primary thyroid MALT lymphoma and papillary thyroid cancer
Authors: Zhang Jianyong , Wu Jing , Sun Liangquan , Chen Yuan , Yu Zhaoyan
Published: May 2024

The mucosa-associated lymphoid tissue (MALT) lymphoma subtype, specifically extranodal marginal zone B-cell lymphoma, is a rare variant. Within this subtype, primary thyroid MALT lymphoma is an uncommon occurrence. The literature provides limited documentation on thyroid MALT lymphomas, as their prevalence is comparatively lower than in other organ sites. The coexistence of papillary thyroid carcinoma (PTC) and thyroid MALT lymphomas is exceedingly rare. It presents a rare case of primary thyroid MALT lymphoma accompanied by PTC, thyroid lymphoma not being considered before surgery. A 64-year-old female patient, who had been experiencing symptoms related to a substantial thyroid tumor for a duration of three years, she refused to do a needle biopsy before surgery and expressed a preference for surgical resection. Consequently, the patient underwent a total thyroidectomy along with lymphadenectomy of the central compartment. A histological examination subsequently confirmed the presence of papillary thyroid carcinoma (PTC) and mucosa-associated lymphoid tissue (MALT) lymphoma. Due to the favorable response of the MALT lymphoma to local treatment and the absence of metastasis in other organs, no further treatment was administered for the MALT lymphoma following the surgery. Currently, the patient exhibits no signs of tumor recurrence based on ultrasound and laboratory evaluations. We also provide an overview of the clinical findings on PTC and MALT lymphoma patients already reported and discuss the possible treatment strategy.
Antioxidant insights: investigating the protective role of oxidative balance in inflammatory bowel disease
Authors: Li Fan , Chang Yu , Wang Zhaodi , Wang Zhi , Zhao Qi , Han Xiaoping , Xu Zifeng , Yu Chanjiao , Liu Yue , Chang Shiyu , Li Hongyan , Hu Sileng , Li Yuqin , Tang Tongyu
Published: May 2024

Background

Limited studies have investigated the relationship between systemic oxidative stress and inflammatory bowel disease (IBD). The purpose of this study was to explore the relationship between oxidative balance score (OBS) and IBD.

Methods

We included 175,808 participants from the UK Biobank database from 2006 to 2010. OBS scores were calculated based on 22 lifestyle and dietary factors. Multiple variable Cox proportional regression models, as well as gender stratification and subgroup analysis, were utilized to investigate the relationship between OBS and IBD.

Results

There is a significant negative correlation between OBS and the occurrence of IBD, ulcerative colitis (UC), and Crohn’s disease (CD). Additionally, OBS is significantly negatively correlated with intestinal obstruction in CD patients. Gender stratified analysis suggest a significant correlation between OBS and CD in female patients, particularly pronounced in those under 60 years old. Sensitivity analysis indicates a significant negative correlation between lifestyle-related OBS and diet-related OBS with the occurrence of CD in females, diet-related OBS is negatively correlated with CD in males.

Conclusion

OBS showed a significant negative correlation with IBD, especially in female CD patients. This study underscores the importance of antioxidant diet and lifestyle, which may provide a greater advantage for female CD patients.
Insight into the current genomic diversity, conservation status and population structure of Tunisian Barbarine sheep breed
Authors: Giovannini Samira , Chessari Giorgio , Riggio Silvia , Marletta Donata , Sardina Maria Teresa , Mastrangelo Salvatore , Sarti Francesca Maria
Published: May 2024

Local livestock breeds play a crucial role in global biodiversity, connecting natural and human-influenced environments and contributing significantly to ecosystem services. While commercial breeds dominate industrial systems, local livestock breeds in developing countries, like Barbarine sheep in Tunisia, are vital for food security and community maintenance. The Tunisian Barbarine sheep, known for its adaptability and distinctive fat-tailed morphology, faces challenges due to historical crossbreeding. In this study, the Illumina Ovine SNP50K BeadChip array was used to perform a genome-wide characterization of Tunisian Barbarine sheep to investigate its genetic diversity, the genome structure, and the relationship within the context of Mediterranean breeds. The results show moderate genetic diversity and low inbreeding. Runs of Homozygosity analysis find genomic regions linked to important traits, including fat tail characteristics. Genomic relationship analysis shows proximity to Algerian thin-tailed breeds, suggesting crossbreeding impacts. Admixture analysis reveals unique genetic patterns, emphasizing the Tunisian Barbarine’s identity within the Mediterranean context and its closeness to African breeds. Current results represent a starting point for the creation of monitoring and conservation plans. In summary, despite genetic dilution due to crossbreeding, the identification of genomic regions offers crucial insights for conservation. The study confirms the importance of preserving unique genetic characteristics of local breeds, particularly in the face of ongoing crossbreeding practices and environmental challenges. These findings contribute valuable insights for the sustainable management of this unique genetic reservoir, supporting local economies and preserving sheep species biodiversity.
Use of the linear regression method to evaluate population accuracy of predictions from non-linear models
Authors: Yu Haipeng , Fernando Rohan L. , Dekkers Jack C. M.
Published: May 2024

Background

To address the limitations of commonly used cross-validation methods, the linear regression method (LR) was proposed to estimate population accuracy of predictions based on the implicit assumption that the fitted model is correct. This method also provides two statistics to determine the adequacy of the fitted model. The validity and behavior of the LR method have been provided and studied for linear predictions but not for nonlinear predictions. The objectives of this study were to 1) provide a mathematical proof for the validity of the LR method when predictions are based on conditional means, regardless of whether the predictions are linear or non-linear 2) investigate the ability of the LR method to detect whether the fitted model is adequate or inadequate, and 3) provide guidelines on how to appropriately partition the data into training and validation such that the LR method can identify an inadequate model.

Results

We present a mathematical proof for the validity of the LR method to estimate population accuracy and to determine whether the fitted model is adequate or inadequate when the predictor is the conditional mean, which may be a non-linear function of the phenotype. Using three partitioning scenarios of simulated data, we show that the one of the LR statistics can detect an inadequate model only when the data are partitioned such that the values of relevant predictor variables differ between the training and validation sets. In contrast, we observed that the other LR statistic was able to detect an inadequate model for all three scenarios.

Conclusion

The LR method has been proposed to address some limitations of the traditional approach of cross-validation in genetic evaluation. In this paper, we showed that the LR method is valid when the model is adequate and the conditional mean is the predictor, even when it is a non-linear function of the phenotype. We found one of the two LR statistics is superior because it was able to detect an inadequate model for all three partitioning scenarios (i.e., between animals, by age within animals, and between animals and by age) that were studied.
Poly-l-lactic acid microspheres delay aging of epidermal stem cells in rat skin
Authors: Dong Yunxian , Zhang Youliang , Yu Hao , Zhou Lingcong , Zhang Yaan , Wang Haibin , Hu Zhicheng , Luo Shengkang
Published: May 2024

Objective

Injectable skin fillers offer a wider range of options for cutaneous anti-aging and facial rejuvenation. PLLA microspheres are increasingly favored as degradable and long-lasting fillers. The present study focused solely on the effect of PLLA on dermal collagen, without investigating its impact on the epidermis. In this study, we investigated the effects of PLLA microspheres on epidermal stem cells (EpiSCs).

Methods

Different concentrations of PLLA microspheres on epidermal stem cells (EpiSCs) in vitro through culture, and identification of primary rat EpiSCs. CCK-8 detection, apoptosis staining, flow cytometry, Transwell assay, wound healing assay, q-PCR analysis, and immunofluorescence staining were used to detect the effects of PLLA on EpiSCs. Furthermore, we observed the effect on the epidermis by injecting PLLA into the dermis of the rat skin in vivo.

Results

PLLA microspheres promote cell proliferation and migration while delaying cell senescence and maintaining its stemness. In vitro, Intradermal injection of PLLA microspheres in the rat back skin resulted in delayed aging, as evidenced by histological and immunohistochemical staining of the skin at 2, 4, and 12 weeks of follow-up.

Conclusion

This study showed the positive effects of PLLA on rat epidermis and EpiSCs, while providing novel insights into the anti-aging mechanism of PLLA.
Initial microbiome and tree root status structured the soil microbial community discrepancy of the subtropical pine-oak forest in a large urban forest park
Authors: Tian Kai , Chen Shaoming , Ye Rumeng , Xie Yanghe , Yao Lunguang , Lin Hong
Published: May 2024

Plant–microbe–soil interactions control over the forest biogeochemical cycling. Adaptive plant–soil interactions can shape specific microbial taxa in determining the ecosystem functioning. Different trees produce heterogeneous soil properties and can alter the composition of soil microbial community, which is relevant to the forest internal succession containing contrasting stand types such as the pine-oak forests. Considering representative microbial community characteristics are recorded in the original soil where they had adapted and resided, we constructed a soil transplant incubation experiment in a series of in situ root-ingrowth cores in a subtropical pine-oak forest, to simulate the vegetational pine-oak replacement under environmental succession. The responsive bacterial and fungal community discrepancies were studied to determine whether and how they would be changed. The pine and oak forest stands had greater heterogeneity in fungi composition than bacteria. Original soil and specific tree root status were the main factors that determined microbial community structure. Internal association network characters and intergroup variations of fungi among soil samples were more affected by original soil, while bacteria were more affected by receiving forest. Specifically, dominant tree roots had strong influence in accelerating the fungi community succession to adapt with the surrounding forest. We concluded that soil microbial responses to forest stand alternation differed between microbiome groups, with fungi from their original forest possessing higher resistance to encounter a new vegetation stand, while the bacteria community have faster resilience. The data would advance our insight into local soil microbial community dynamics during ecosystem succession and be helpful to enlighten forest management.
The effect of physical exercise intervention on the ability of daily living in patients with Alzheimer’s dementia: a meta-analysis
Authors: Liu Chenyu , Gao Shiying , Li Shanshan
Published: May 2024

Objective

To systematically evaluate the effect of physical exercise intervention on the activities of daily living (ADL) on patients with Alzheimer’s dementia (AD) and explore the optimal exercise scheme.

Methods

PubMed, EMBASE, the Cochrane Library, Web of Science, and Science Direct databases were searched from 1987 to December 2023 to collect randomized controlled trials (RCTs). Two investigators independently screened the literature and extracted data according to the inclusion and exclusion criteria. The quality of the included studies was evaluated using Cochrane Review Manager 5.3. And STATA 16.0 was used for performing the meta-analysis.

Results

Fifteen randomized controlled trials were included. The results of the meta-analysis showed that physical exercise had a positive effect on the improvement of ADL in patients with AD [standardized mean difference (SMD) = 0.312, 95% confidence interval (CI 0.039–0.585), P = 0.02], and the difference was statistically significant. The results of subgroup analysis showed that anaerobic exercises such as strength and balance training with a medium cycle of 12–16 weeks and lasting 30–45 min each time were more ideal for the improvement of basic daily living ability of AD patients.

Conclusion

Physical exercise can effectively improve activities of daily living in patients with Alzheimer’s dementia and it may be a potential non-drug treatment for AD patients.
Peripheral immunity involvement in the cognitive impairment of sporadic amyotrophic lateral sclerosis
Authors: Yang Tianmi , Wei Qianqian , Li Chunyu , Ou Ruwei , Lin Junyu , Cheng Yangfan , Xiao Yi , Shang Huifang
Published: May 2024

Background

Recent research has indicated the significance of immune activation in amyotrophic lateral sclerosis (ALS). However, the impact of peripheral immunity on cognitive impairment in sporadic ALS remains poorly characterized. Therefore, we aim to assess the relationship between peripheral immune parameters and cognitive impairment in patients with sporadic ALS.

Methods

A case–control study involving 289 patients with sporadic ALS was conducted. All participants underwent cognitive assessment and measurements of blood immune parameters. The main outcomes included adjusted odds ratios (ORs) in multivariate logistic regression analysis and adjusted coefficients in a multivariate linear regression model. Sensitivity analysis was performed with stratification by the King’s clinical stage.

Results

Cognitive impairment was observed in 98 (33.9%) patients. Higher counts of leukocyte (OR, 0.53; 95% CI, 0.29 to 0.95; p = 0.03), neutrophil (OR, 0.48; 95% CI, 0.26 to 0.88; p = 0.02), and monocyte (OR, 0.33; 95% CI, 0.18 to 0.60; p < 0.001) were significantly associated with better cognitive preformence in sporadic ALS, particularly among patients in King’s clinical stages 1 and 2. Conversely, a higher percentage of CD4+ T cells was linked to an increased risk of cognitive impairment (OR, 2.79; 95% CI, 1.52 to 5.09; p = 0.001), particularly evident in patients in King’s clinical stage 3.

Conclusion

These results highlight the involvement of peripheral immunity in the cognitive impairment of sporadic ALS and suggest dynamic and intricate roles that vary across disease stages. Elucidating the links between immunity and ALS sheds light on the pathophysiological mechanisms underlying this fatal neurodegenerative disorder and informs potential immunotherapeutic strategies.
Multilevel bivariate analysis of the association between high-risk fertility behaviors of birth and stunting with associated risk factors in Ethiopia
Authors: Fenta Wondaya , Zeru Melkamu A.
Published: May 2024

Introduction

Currently, the linkage between high-risk fertility behavior of birth and the occurrence of stunting among children under the age of 5 continues to be a significant public health problem in developing countries, including Ethiopia. This issue poses a threat to the health and overall wellbeing of under-five children. Thus, the main objective of this study was to examine the association between high-risk fertility behavior of birth and the stunting status of children and associated factors.

Methods

The data used for this study were extracted from the recent Ethiopian Mini Demographic and Health Survey data in 2019. A total weighted sample of 4,969 under-five children was included in this study, and the relevant data were extracted from those samples. The multilevel bivariate analysis was used to assess the association between high-risk fertility behavior of birth and the stunting status of under-five children in Ethiopia.

Results

It was found that, out of 4,997 under-five children, 24% of under-five children experienced stunting as a result of high-risk fertility behavior of birth. Our study also revealed an intra-class correlation of 0.2, indicating that 20% of the variability in both high-risk fertility behaviors of birth and stunting can be attributed to differences between communities. Furthermore, there was a statistically significant association between high-risk fertility behavior of birth and the stunting status of children under the age of 5 years [AOR = 8.5, 95% CI: (5.58, 18.70)]. Similarly, the stunting status of birth among boys was 1.36 times greater than the estimated odds of the stunting status of birth among girls [AOR = 1.36, 95% CI: (1.19, 1.55)].

Conclusion

This study found that there was a significant statistical association between high-risk fertility behavior of birth and stunting status of under-five children. Specifically, children born to mothers under 18 years and in households with high parity were identified as the main risk factors for child stunting. Furthermore, health-related education, improved access to maternal healthcare, and training interventions were associated with high-risk fertility behavior during birth and child stunting. The study suggests that regular health assessments and early interventions for infants born to mothers with high-risk reproductive characteristics are crucial to reducing the impact of child stunting under 5 years of age.