bluuebunny/crossref_metadata_2025 huggingface dataset:
Emerging Imaging Modalities in Regenerative Medicine
Authors: Stacy Mitchel R. , Sinusas Albert J.
Published: January 2015

The field of regenerative medicine has experienced considerable growth in recent years as the translation of pre-clinical biomaterials and cell- and gene-based therapies begin to reach clinical application. Until recently, the ability to monitor the serial responses to therapeutic treatments has been limited to post-mortem tissue analyses. With improvements in existing imaging modalities and the emergence of hybrid imaging systems, it is now possible to combine information related to structural remodeling with associated molecular events using non-invasive imaging. This review summarizes the established and emerging imaging modalities that are available for in vivo monitoring of clinical regenerative medicine therapies and discusses the strengths and limitations of each imaging modality.
An evolutionarily‐unique heterodimeric voltage‐gated cation channel found in aphids
Authors: Amey Joanna S. , O'Reilly Andrias O. , Burton Mark J. , Puinean Alin M. , Mellor Ian R. , Duce Ian R. , Field Linda M. , Wallace B.A. , Williamson Martin S. , Davies T.G. Emyr
Published: January 2015

We describe the identification in aphids of a unique heterodimeric voltage‐gated sodium channel which has an atypical ion selectivity filter and, unusually for insect channels, is highly insensitive to tetrodotoxin. We demonstrate that this channel has most likely arisen by adaptation (gene fission or duplication) of an invertebrate ancestral mono(hetero)meric channel. This is the only identifiable voltage‐gated sodium channel homologue in the aphid genome(s), and the channel's novel selectivity filter motif (DENS instead of the usual DEKA found in other eukaryotes) may result in a loss of sodium selectivity, as indicated experimentally in mutagenised Drosophila channels.
ECONOMIC IMPACT OF ALTERNATIVE FMD EMERGENCY VACCINATION STRATEGIES IN THE MIDWESTERN UNITED STATES
Authors: SCHROEDER TED C. , PENDELL DUSTIN L. , SANDERSON MICHAEL W. , MCREYNOLDS SARA
Published: January 2015

An outbreak of foot-and-mouth disease (FMD) in the United States would likely result in major costs to producers, consumers, and government. How animal health officials manage such an outbreak has substantial impact on probable losses. Without an emergency FMD vaccination strategy, producer and consumer losses of an FMD outbreak in the midwestern United States would likely approach $188 billion, and government costs would likely exceed $11 billion. In contrast, a high-capacity emergency vaccination program together with a large vaccination zone would reduce median consumer and producer losses to approximately $56 billion and government costs to a little more than $1 billion.
COMPARING CARCASS END-POINT AND PROFIT MAXIMIZATION DECISION RULES USING DYNAMIC NONLINEAR GROWTH FUNCTIONS
Authors: MAPLES JOSHUA G. , COATNEY KALYN T. , RILEY JOHN M. , KARISCH BRANDI B. , PARISH JANE A. , VANN RHONDA C.
Published: January 2015

This article develops a market timing decision rule for cattle feeders based on profit maximization. We then compare it with the “status quo” strategy of feeding cattle to a targeted carcass end point. We estimate individual nonlinear dynamic growth functions to derive each animal's value of the marginal product in relation to days on feed. Given individual marginal factor costs, our results indicate that the use of a profit maximization rule could have increased average profits by $16.56 to $21.09 per head for the cattle of known age, and $7.67 to $11.32 per head if age was unknown.
Genetic basis of human left–right asymmetry disorders
Authors: Deng Hao , Xia Hong , Deng Sheng
Published: January 2015

Humans and other vertebrates exhibit left–right (LR) asymmetric arrangement of the internal organs, and failure to establish normal LR asymmetry leads to internal laterality disorders, includingsitus inversusandheterotaxy.Situs inversusis complete mirror-imaged arrangement of the internal organs along LR axis, whereasheterotaxyis abnormal arrangement of the internal thoraco-abdominal organs across LR axis of the body, most of which are associated with complex cardiovascular malformations. Both disorders are genetically heterogeneous with reduced penetrance, presumably because of monogenic, polygenic or multifactorial causes. Research in genetics of LR asymmetry disorders has been extremely prolific over the past 17 years, and a series of loci and disease genes involved insitus inversusandheterotaxyhave been described. The review highlights the classification, chromosomal abnormalities, pathogenic genes and the possible mechanism of human LR asymmetry disorders.
Turkey’s Small Capital, A Player from the Start: Relations with the State and Big Capital
Authors: BALIKÇI EMRE
Published: January 2015

This article aims to shed light on the early history of small-scale capital in Turkey. Turkey’s paradigm of development in the 1960s and 1970s, as in other belatedly industrializing countries, meant active state involvement, generally in favor of big capital. This emphasis on the large players has caused small capital’s influence on the era’s state policies to be largely overlooked. This article argues that small capital, popularized in the 1990s with the concept “Anatolian capital,” has deeper roots in Turkish economic and business history than formerly thought.
Design and current progress of the Apollon 10 PW project
Authors: Zou J.P. , Le Blanc C. , Papadopoulos D.N. , Chériaux G. , Georges P. , Mennerat G. , Druon F. , Lecherbourg L. , Pellegrina A. , Ramirez P. , Giambruno F. , Fréneaux A. , Leconte F. , Badarau D. , Boudenne J.M. , Fournet D. , Valloton T. , Paillard J.L. , Veray J.L. , Pina M. , Monot P. , Chambaret J.P. , Martin P. , Mathieu F. , Audebert P. , Amiranoff F.
Published: January 2015

The objective of the Apollon project is the generation of 10 PW peak power pulses of 15 fs at 1 shot/minute. In this paper the Apollon facility design, the technological challenges and the current progress of the project will be presented.
Relationship Satisfaction, Conflict and Psychological Distress: The Impact of Combat Deployment to Afghanistan on the Romantic Partners of Australian Army Personnel
Authors: Turner Joanna , Chessor Danuta
Published: January 2015

Coping with psychological suffering after combat deployment has been identified across a diverse range of wars and countries as having the potential to negatively influence the long-term wellbeing of female partners of veterans. The aim of the study was to explore whether romantic partners of veterans (N = 97) suffered higher levels of psychological distress and destructive relationship conflict, lower relationship satisfaction and perceived social support when compared to female Australians in the civilian population (N = 87). Australian participants completed an anonymous online survey, and overall means were calculated for each group and compared using independent samples t tests. Results from the study indicated strong support for all research hypotheses in the expected directions. Research findings suggest that Australian females romantically involved with Afghanistan War veterans are more vulnerable to experiencing relationship dysfunction and are at an increased risk of impaired psychological health in the Australian population.
Getting By With a Little Help From My Friends: A Pilot Study of the Measurement and Stability of Positive Social Support From Significant Others for Adolescents
Authors: Bowles Terry V. , Hattie John A.
Published: January 2015

Based on research into adult social support and the ecological model of development, we sought to redefine and establish the levels and nature of support provided to Year 7 (n= 52), 9 (n= 52) and Year 11 (n= 33) adolescents over a period of 3 months. A questionnaire to identify who provided support to adolescents was developed to measure instrumental, informational and emotional support, and add siblings to the primary support network. Factor analysis confirmed the expected four-factor model of support, with parents, teachers, siblings and friends providing different levels and priorities of support. Results indicated high levels of internal consistency and test–retest reliability. Trends in the amount of social support generally showed a decrease from Time 1 to Time 2, significantly so from parents and teachers. Females indicated they received significantly more support from friends in comparison with males, regardless of year level. Year 7 students indicated significantly higher support from parents and teachers. Importantly, this study showed the general decline of social support from early to late adolescence, and the relative consistency of social support for male and female adolescents. The different types of supports provided to the individuals in the adolescents’ social network are discussed.
VIOLENCE AND EVERYDAY INTERACTIONS BETWEEN KATANGESE AND KASAIANS: MEMORY AND ELECTIONS IN TWO KATANGA CITIES
Authors: Vinckel Sandrine
Published: January 2015

Since the mass violence committed by Katangese against non-natives – mostly Kasaians – in the early 1990s in the Katanga province (Democratic Republic of Congo), Katangese and Kasaians have eschewed subjects relating to the past violence in their daily interactions. However, during the November 2011 presidential and legislative election period, expressions linked to the past violence, such as ‘This time, you will go back home by foot’ or ‘This time, you will not drive us out. We will fight’, were common. The paper documents and analyses how Kasaians and Katangese dealt with the memory of the violence during this election period, in Likasi and Kolwezi, two cities particularly affected by violence. Based on qualitative fieldwork research conducted between November 2011 and January 2012, the paper understands the November 2011 election as being a crisis situation informed by the fear of a violent outbreak in the event of the victory of Etienne Tshisekedi, leader of the opposition and a Kasaian. This crisis situation led to the simplification and polarization of collective identities: whether friend, neighbour or colleague, a person was perceived only as a Kasaian or a Katangese. In such a context, routine practices of coexistence based on self-censorship and avoidance tended to disappear.
The global implications of the early surviving rock art of greater Southeast Asia
Authors: Taçon Paul S.C. , Tan Noel Hidalgo , O’Connor Sue , Xueping Ji , Gang Li , Curnoe Darren , Bulbeck David , Hakim Budianto , Sumantri Iwan , Than Heng , Sokrithy Im , Chia Stephen , Khun-Neay Khuon , Kong Soeung
Published: January 2015

The rock art of Southeast Asia has been less thoroughly studied than that of Europe or Australia, and it has generally been considered to be more recent in origin. New dating evidence from Mainland and Island Southeast Asia, however, demonstrates that the earliest motifs (hand stencils and naturalistic animals) are of late Pleistocene age and as early as those of Europe. The similar form of the earliest painted motifs in Europe, Africa and Southeast Asia suggests that they are the product of a shared underlying behaviour, but the difference in context (rockshelters) indicates that experiences in deep caves cannot have been their inspiration.
Foragers, fishers and farmers: origins of the Taiwanese Neolithic
Authors: Hung Hsiao-chun , Carson Mike T.
Published: January 2015

The Neolithic of Taiwan represents the first stage in the expansion of Austronesian-speaking peoples through the Pacific. Settlement and burial evidence from the Tapenkeng (TKP) or Dabenkeng culture demonstrates the development of the early Taiwanese Neolithic over a period of almost 2000 years, from its origin in the pre-TPK of the Pearl River Delta and south-eastern coastal China. The first TPK communities of Taiwan pursued a mixed coastal foraging and horticultural lifestyle, but by the late TPK rice and millet farming were practised with extensive villages and large settlements. The broad-spectrum subsistence diversity of the Taiwanese Neolithic was an important factor in facilitating the subsequent expansion of Austronesian-speaking peoples to the Philippines and beyond.
Archaeology, genetics and a population bottleneck in prehistoric Finland
Authors: Sundell Tarja , Kammonen Juhana , Halinen Petri , Pesonen Petro , Onkamo Päivi
Published: January 2015

The long-term history of prehistoric populations is a challenging but important subject that can now be addressed through combined use of archaeological and genetic evidence. In this study a multidisciplinary team uses these approaches to document the existence of a major population bottleneck in Finland during the Late Neolithic period, the effects of which are still detectable in the genetic profile of the Finnish population today. The postglacial recolonisation of Finland was tracked through space and time using radiocarbon dates and stone artefact distributions to provide a robust framework of evidence against which the genetic simulations could be compared.
Dating the Thera (Santorini) eruption: archaeological and scientific evidence supporting a high chronology
Authors: Manning Sturt W. , Höflmayer Felix , Moeller Nadine , Dee Michael W. , Ramsey Christopher Bronk , Fleitmann Dominik , Higham Thomas , Kutschera Walter , Wild Eva Maria
Published: January 2015

The date of the Late Bronze Age Minoan eruption of the Thera volcano has provoked much debate among archaeologists, not least in a recent issue of Antiquity (‘Bronze Age catastrophe and modern controversy: dating the Santorini eruption’, March 2014). Here, the authors respond to those recent contributions, citing evidence that closes the gap between the conclusions offered by previous typological, stratigraphic and radiometric dating techniques. They reject the need to choose between alternative approaches to the problem and make a case for the synchronisation of eastern Mediterranean and Egyptian chronologies with agreement on a ‘high’ date in the late seventeenth century BC for the Thera eruption.
Ceramics, trade, provenience and geology: Cyprus in the Late Bronze Age
Authors: Grave Peter , Kealhofer Lisa , Marsh Ben , Schoop Ulf-Dietrich , Seeher Jürgen , Bennett John W. , Stopic Attila
Published: January 2015

The island of Cyprus was a major producer of copper and stood at the heart of east Mediterranean trade networks during the Late Bronze Age. It may also have been the source of the Red Lustrous Wheelmade Ware that has been found in mortuary contexts in Egypt and the Levant, and in Hittite temple assemblages in Anatolia. Neutron Activation Analysis (NAA) has enabled the source area of this special ceramic to be located in a geologically highly localised and geochemically distinctive area of western Cyprus. This discovery offers a new perspective on the spatial organisation of Cypriot economies in the production and exchange of elite goods around the eastern Mediterranean at this time.
Shifting materials: variability, homogeneity and change in the beaded ornaments of the Western Zhou
Authors: Hommel Peter , Sax Margaret
Published: January 2015

Academic interest in the elaborate bead assemblages recovered from graves of the Western Zhou elite has grown in recent years. Beads and beaded ornaments have been seen as both markers of external contact and evidence of change in the Zhou ritual system. Recent study of these bead assemblages, however, indicates that they may also have reflected shifting political circumstances. The use of different bead materials and forms suggests a trend to centralised production and control of manufacture, particularly from the later tenth century BC. The authors correlate a move towards readily manufactured materials with evidence for widespread elite intermarriage, and consider a possible tension between production and the socio-political strategies of the Zhou court.
Stone architecture, monumentality and the rise of the early Tongan chiefdom
Authors: Clark Geoffrey , Reepmeyer Christian
Published: January 2015

Monumental construction is commonly associated with the rise of complex societies and frequently supported the ceremonies and ideologies that were instrumental in the creation of the new social order. Recent fieldwork at Heketa in eastern Tongatapu recorded stone-built platforms for houses and seats, and a three-tiered tomb and trilithon. Tongan tradition and archaeology combine to show that these were the setting for new ceremonies instituted by the emergent Tu’i Tonga lineage in the fourteenth century AD as they laid the foundations of the early Tongan chiefdom. Key to their success were activities that emphasised the sacred origins of the living Tu’i Tonga, including the drinking of kava and the presentation of first fruits to the chiefs.
Sitting on the Wall, Looking in: Some Reflections on the Critique of International Criminal Law
Authors: JACOBS DOV
Published: January 2015

This editorial explores some methodological difficulties that might be faced by the practice of the critique of international criminal law (ICL). It more particularly explores what it might mean to do an ‘internal’ critique of ICL, both on a disciplinary level and an intra-disciplinary level. The editorial also addresses two important issues: (i) the ambiguities of the normative agendas of critical legal scholars; and (ii) the difficulty of dialogue between critical legal scholars and positivists. The editorial concludes with the fact that while disciplinary dialogue might not always be possible, it will always take place on a personal, more complex level, in the Leiden Journal of International Law (LJIL) as elsewhere.
Worldwide trends in dietary sugars intake
Authors: Wittekind Anna , Walton Janette
Published: January 2015

Estimating trends in dietary intake data is integral to informing national nutrition policy and monitoring progress towards dietary guidelines. Dietary intake of sugars is a controversial public health issue and guidance in relation to recommended intakes is particularly inconsistent. Published data relating to trends in sugars intake are relatively sparse. The purpose of the present review was to collate and review data from national nutrition surveys to examine changes and trends in dietary sugars intake. Only thirteen countries (all in the developed world) appear to report estimates of sugars intake from national nutrition surveys at more than one point in time. Definitions of dietary sugars that were used include ‘total sugars’, ‘non-milk extrinsic sugars’, ‘added sugars’, sucrose' and ‘mono- and disaccharides’. This variability in terminology across countries meant that comparisons were limited to within countries. Hence trends in dietary sugars intake were examined by country for the whole population (where data permitted), and for specific or combined age and sex subpopulations. Findings indicate that in the majority of population comparisons, estimated dietary sugars intake is either stable or decreasing in both absolute (g/d) and relative (% energy) terms. An increase in sugars intake was observed in few countries and only in specific subpopulations. In conclusion, the findings from the present review suggest that, in the main, dietary sugars intake are decreasing or stable. A consistent approach to estimation of dietary sugars intake from national nutrition surveys is required if more valid estimates of changes in dietary sugars intakes are required in the future.
Validation and reproducibility of a semi-quantitative FFQ as a measure of dietary intake in adults from Puerto Rico
Authors: Palacios Cristina , Trak Maria Angelica , Betancourt Jesmari , Joshipura Kaumudi , Tucker Katherine L
Published: January 2015

Objective

We aimed to assess the relative validity and reproducibility of a semi-quantitative FFQ in Puerto Rican adults.

Design

Participants completed an FFQ, followed by a 6 d food record and a second administration of the FFQ, 30 d later. All nutrients were log transformed and adjusted for energy intake. Statistical analyses included correlations, paired t tests, cross-classification and Bland–Altman plots.

Setting

Medical Sciences Campus, University of Puerto Rico.

Subjects

Convenience sample of students, employees and faculty members (n 100, ≥21 years). Data were collected in 2010.

Results

A total of ninety-two participants completed the study. Most were young overweight females. All nutrients were significantly correlated between the two FFQ, with an average correlation of 0·61 (range 0·43–0·73) and an average difference of 4·8 % between them. Most energy-adjusted nutrients showed significant correlations between the FFQ and food record, which improved with de-attenuation and averaged 0·38 (range 0·11–0·63). The lowest non-significant correlations (≤0·20) were for trans-fat, n 3 fatty acids, thiamin and vitamin E. Intakes assessed by the FFQ were higher than those from the food record by a mean of 19 % (range 4–44 %). Bland–Altman plots showed that there was a systematic trend towards higher estimates with the FFQ, particularly for energy, carbohydrate and Ca. Most participants were correctly classified into the same or adjacent quintile (average 66 %) by both methods with only 3 % gross misclassification.

Conclusions

This semi-quantitative FFQ is a tool that offers relatively valid and reproducible estimates of energy and certain nutrients in this group of mostly female Puerto Ricans.
A strong-field driver in the single-cycle regime based on self-compression in a kagome fibre
Authors: Balciunas T. , Fourcade-Dutin C. , Fan G. , Witting T. , Voronin A. A. , Zheltikov A. M. , Gerome F. , Paulus G. G. , Baltuska A. , Benabid F.
Published: January 2015

Over the past decade intense laser fields with a single-cycle duration and even shorter, subcycle multicolour field transients have been generated and applied to drive attosecond phenomena in strong-field physics. Because of their extensive bandwidth, single-cycle fields cannot be emitted or amplified by laser sources directly and, as a rule, are produced by external pulse compression—a combination of nonlinear optical spectral broadening followed up by dispersion compensation. Here we demonstrate a simple robust driver for high-field applications based on this Kagome fibre approach that ensures pulse self-compression down to the ultimate single-cycle limit and provides phase-controlled pulses with up to a 100 μJ energy level, depending on the filling gas, pressure and the waveguide length.
The ligand binding mechanism to purine nucleoside phosphorylase elucidated via molecular dynamics and machine learning
Authors: Decherchi Sergio , Berteotti Anna , Bottegoni Giovanni , Rocchia Walter , Cavalli Andrea
Published: January 2015

The study of biomolecular interactions between a drug and its biological target is of paramount importance for the design of novel bioactive compounds. In this paper, we report on the use of molecular dynamics (MD) simulations and machine learning to study the binding mechanism of a transition state analogue (DADMe–immucillin-H) to the purine nucleoside phosphorylase (PNP) enzyme. Microsecond-long MD simulations allow us to observe several binding events, following different dynamical routes and reaching diverse binding configurations. These simulations are used to estimate kinetic and thermodynamic quantities, such as kon and binding free energy, obtaining a good agreement with available experimental data. In addition, we advance a hypothesis for the slow-onset inhibition mechanism of DADMe–immucillin-H against PNP. Combining extensive MD simulations with machine learning algorithms could therefore be a fruitful approach for capturing key aspects of drug–target recognition and binding.
Optimum periodicity of repeated contractile actions applied in mass transport
Authors: Ahn Sungsook , Lee Sang Joon
Published: January 2015

Dynamically repeated periodic patterns are abundant in natural and artificial systems, such as tides, heart beats, stock prices and the like. The characteristic repeatability and periodicity are expected to be optimized in effective system-specific functions. In this study, such optimum periodicity is experimentally evaluated in terms of effective mass transport using one-valve and multi-valve systems working in contractile fluid flows. A set of nanoscale gating functions is utilized, operating in nanocomposite networks through which permeates selectively pass under characteristic contractile actions. Optimized contractile periodicity exists for effective energy impartment to flow in a one-valve system. In the sequential contractile actions for a multi-valve system, synchronization with the fluid flow is critical for effective mass transport. This study provides fundamental understanding on the various repeated periodic patterns and dynamic repeatability occurring in nature and mechanical systems, which are useful for broad applications.
Effect of the enzyme and PCR conditions on the quality of high-throughput DNA sequencing results
Authors: Brandariz-Fontes Claudia , Camacho-Sanchez Miguel , Vilà Carles , Vega-Pla José Luis , Rico Ciro , Leonard Jennifer A.
Published: January 2015

Library preparation protocols for high-throughput DNA sequencing (HTS) include amplification steps in which errors can build up. In order to have confidence in the sequencing data, it is important to understand the effects of different Taq polymerases and PCR amplification protocols on the DNA molecules sequenced. We compared thirteen enzymes in three different marker systems: simple, single copy nuclear gene and complex multi-gene family. We also tested a modified PCR protocol, which has been suggested to reduce errors associated with amplification steps. We find that enzyme choice has a large impact on the proportion of correct sequences recovered. The most complex marker systems yielded fewer correct reads and the proportion of correct reads was greatly affected by the enzyme used. Modified cycling conditions did reduce the number of incorrect sequences obtained in some cases, but enzyme had a much greater impact on the number of correct reads. Thus, the coverage required for the safe identification of genotypes using one of the low quality enzymes could be seven times larger than with more efficient enzymes in a biallelic system with equal amplification of the two alleles. Consequently, enzyme selection for downstream HTS has important consequences, especially in complex genetic systems.
Building with bubbles: the formation of high surface area honeycomb-like films via hydrogen bubble templated electrodeposition
Authors: Plowman Blake J. , Jones Lathe A. , Bhargava Suresh K.
Published: January 2015

This feature article summarizes recent developments in porous materials obtained through electrodeposition in the presence of H2evolution. We discuss recent applications and present a case for further development of surfaces exhibiting new and improved activity.
Ditopic CMPO-pillar[5]arenes as unique receptors for efficient separation of americium(iii) and europium(iii)
Authors: Fang Yuyu , Yuan Xiangyang , Wu Lei , Peng Zhiyong , Feng Wen , Liu Ning , Xu Dingguo , Li Shoujian , Sengupta Arijit , Mohapatra Prasanta K. , Yuan Lihua
Published: January 2015

A unique host–guest recognition process involving a new class of homoditopic CMPO-pillar[5]arenes and lanthanides was revealed to proceed in a stepwise manner, and correlated to the efficient and selective separation of americium(iii) from europium(iii) under acidic feed conditions.
Visible-light-induced photocatalytic oxytrifluoromethylation of N-allylamides for the synthesis of CF3-containing oxazolines and benzoxazines
Authors: Deng Qiao-Hui , Chen Jia-Rong , Wei Qiang , Zhao Quan-Qing , Lu Liang-Qiu , Xiao Wen-Jing
Published: January 2015

A visible-light-induced photocatalytic oxytrifluoro-methylation reaction of N-allylamides has been described for the efficient synthesis of CF3-containing oxazolines and benzoxazines in generally high yields.
A one-pot strategy to synthesize β-ketophosphonates: silver/copper catalyzed direct oxyphosphorylation of alkynes with H-phosphonates and oxygen in the air
Authors: Chen Xin , Li Xu , Chen Xiao-Lan , Qu Ling-Bo , Chen Jian-Yu , Sun Kai , Liu Zhi-Dong , Bi Wen-Zhu , Xia Ying-Ya , Wu Hai-Tao , Zhao Yu-Fen
Published: January 2015

A highly efficient one-pot strategy has been developed for the synthesis of β-ketophosphonates directly from alkynes and dialkylH-phosphonates in the presence of widely available AgNO3/CuSO4and K2S2O8at room temperature.
Charge density mismatch synthesis of MEI- and BPH-type zeolites in the TEA+–TMA+–Li+–Sr2+ mixed-structure-directing agent system
Authors: Park Min Bum , Ahn Sang Hyun , Ahn Nak Ho , Hong Suk Bong
Published: January 2015

The charge density mismatch synthesis of MEI- and BPH-type zeolites in the TEA+–TMA+–Li+–Sr2+ mixed-structure-directing agent system is described.
The role of copper ions in pathophysiology and fluorescent sensors for the detection thereof
Authors: Verwilst Peter , Sunwoo Kyoung , Kim Jong Seung
Published: January 2015

Copper ions are crucial to life, and some fundamental roles of copper in pathophysiology have been elucidated using fluorescent sensors.
Palladium-catalyzed regioselective allylation of five-membered heteroarenes with allyltributylstannane
Authors: Zhang Sheng , Yu Xiaoqiang , Feng Xiujuan , Yamamoto Yoshinori , Bao Ming
Published: January 2015

Regioselective allylation of five-membered heteroarenes can be achieved using a palladium catalyst via η3-allylpalladium intermediates.
Chirality sensing and size recognition of N-Boc-amino acids by cage-type dimeric lanthanide complexes: chirality detection of N-Boc-aspartate anions via luminescence colour change
Authors: Ito Hiroshi , Shinoda Satoshi
Published: January 2015

A mixture of chiral luminescent macrotricyclic-cyclen-Tb–Eu complexes enabled naked-eye discrimination ofN-Boc-d- andl-aspartatesvialuminescence colour change.
Chalcoplatin, a dual-targeting and p53 activator-containing anticancer platinum(iv) prodrug with unique mode of action
Authors: Ma Lili , Ma Rong , Wang Yiping , Zhu Xiaoyue , Zhang Junliang , Chan Hoi Ching , Chen Xianfeng , Zhang Wenjun , Chiu Sung-Kay , Zhu Guangyu
Published: January 2015

Killing two birds with one stone: a p53 activator was conjugated with cisplatin as a single anticancer agent, leading to synergistically improved cytotoxicity.
Atomistic study of dynamics for metallic filament growth in conductive-bridge random access memory
Authors: Qin Shengjun , Liu Zhan , Zhang Guo , Zhang Jinyu , Sun Yaping , Wu Huaqiang , Qian He , Yu Zhiping
Published: January 2015

The growth dynamics for metallic filaments in conductive-bridge resistive-switching random access memory (CBRAM) are studied using the kinetic Monte Carlo (KMC) method.
Surface enhanced vibrational spectroscopy and first-principles study of l-cysteine adsorption on noble trimetallic Au/Pt@Rh clusters
Authors: Loganathan B. , Chandraboss V. L. , Senthilvelan S. , Karthikeyan B.
Published: January 2015

First-principles study of l-cysteine adsorption on noble trimetallic Au/Pt@Rh clusters has been discussed in the light of SEIRS and theoretical surface complex calculation.
Magnetostructural dynamics of Rieske versus ferredoxin iron–sulfur cofactors
Authors: Ali Md. Ehesan , Staemmler Volker , Marx Dominik
Published: January 2015

The local chemical environment of the [2Fe–2S] cofactor hosted by ferredoxin and Rieske-type proteins is chemically different, which is shown here to result into distinct magnetostructural fingerprints in the frequency window from about 200 to 350 cm−1.
Simulation of X-ray absorption spectra with orthogonality constrained density functional theory
Authors: Derricotte Wallace D. , Evangelista Francesco A.
Published: January 2015

Orthogonality constrained density functional theory is used to predict the near-edge X-ray absorption spectrum of adenine and thymine.
Estimating successive pKa values of polyprotic acids from ab initio molecular dynamics using metadynamics: the dissociation of phthalic acid and its isomers
Authors: Tummanapelli Anil Kumar , Vasudevan Sukumaran
Published: January 2015

pKa values of polyprotic acids estimated from ab initio molecular dynamics computation of the change in free energy upon dissociation.
Imaging of β-amyloid plaques by near infrared fluorescent tracers: a new frontier for chemical neuroscience
Authors: Staderini Matteo , Martín María Antonia , Bolognesi Maria Laura , Menéndez J. Carlos
Published: January 2015

Near infrared (NIR) imaging is a promising and non-invasive method to visualize amyloid plaquesin vivo.
Pyrite FeS2for high-rate and long-life rechargeable sodium batteries
Authors: Hu Zhe , Zhu Zhiqiang , Cheng Fangyi , Zhang Kai , Wang Jianbin , Chen Chengcheng , Chen Jun
Published: January 2015

High-performance rechargeable Na/FeS2batteries showing only the intercalation reaction are obtained by selecting a NaSO3CF3/diglyme electrolyte and tuning the cut-off voltage to 0.8 V.
Localizing and inducing primary nucleation
Authors: Hammadi Zoubida , Grossier Romain , Zhang Shuheng , Ikni Aziza , Candoni Nadine , Morin Roger , Veesler Stéphane
Published: January 2015

Do the differing properties of materials influence their nucleation mechanisms? We present different experimental approaches to study and control nucleation, and shed light on some of the factors affecting the nucleation process.
Facile route to conformal hydrotalcite coatings over complex architectures: a hierarchically ordered nanoporous base catalyst for FAME production
Authors: Creasey Julia J. , Parlett Christopher M. A. , Manayil Jinesh C. , Isaacs Mark A. , Wilson K. , Lee Adam F.
Published: January 2015

Conformal hydrotalcite coatings over hierarchically-ordered SBA-15 exhibit exceptional activity for transesterification of bulky triglycerides.
Effect of torrefaction on biomass structure and hydrocarbon production from fast pyrolysis
Authors: Neupane S. , Adhikari S. , Wang Z. , Ragauskas A. J. , Pu Y.
Published: January 2015

Torrefaction has been shown to improve the chemical composition of bio-oils produced from fast pyrolysis by lowering its oxygen content and enhancing the aromatic yield.
Design, facile synthesis and anthelmintic activity of new O-substituted 6-methoxybenzothiazole-2-carbamates
Authors: Omar A. Mohsen M. E. , Aboulwafa Omaima M. , Issa Doaa A. E. , El-Shokrofy May M. S. , Amr May E. , El-Ashmawy Ibrahim M.
Published: January 2015

Hypothesis for designing 6-substituted benzothiazolecarbamate prototype anthelmintics having diversities in flexibility and rigidity of substituents with different polar nature and hydrophilic–lipophilic properties.
Visible light-induced photocatalytic activity of modified titanium(iv) oxide with zero-valent bismuth clusters
Authors: Kouamé Natalie A. , Alaoui Ouafa Tahiri , Herissan Alexandre , Larios Eduardo , José-Yacaman Miguel , Etcheberry Arnaud , Colbeau-Justin Christophe , Remita Hynd
Published: January 2015

Surface modification of TiO2 with zero-valent Bi nanoclusters induces high photocatalytic activity under visible light.
The influence of the nature of organosilane surfactants and their concentration on the formation of hierarchical FAU-type zeolite nanosheets
Authors: Rioland Guillaume , Albrecht Sebastien , Josien Ludovic , Vidal Loic , Daou T. Jean
Published: January 2015

Hierarchical FAU-type zeolite nanosheets were successfully synthesized by using different organosilane surfactants.
Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis
Authors: Labby Kristin J. , Watsula Stoyan G. , Garneau-Tsodikova Sylvie
Published: January 2015

This highlight focuses on one of Nature's key strategies to doubly modify an amino acid during nonribosomal peptide biosynthesis by using a single enzyme, an interrupted adenylation domain.
Lanthanides post-functionalized nanocrystalline metal–organic frameworks for tunable white-light emission and orthogonal multi-readout thermometry
Authors: Zhou You , Yan Bing
Published: January 2015

We demonstrated white-light emission and multi-readout thermometry in nanocrystalline luminescent metal–organic frameworks, which are preparedviapostsynthetic functionalization with lanthanides of a robust UiO MOF.
Structural characterization and functional evaluation of lactoferrin–polyphenol conjugates formed by free-radical graft copolymerization
Authors: Liu Fuguo , Sun Cuixia , Yang Wei , Yuan Fang , Gao Yanxiang
Published: January 2015

Covalent modifications of lactoferrin with EGCG, chlorogenic acid and gallic acid were performed by adopting a free-radical grafting procedure in aqueous media and they affect both structural and functional properties of the protein.
Synthesis and in vitro phantom NMR and MRI studies of fully organic free radicals, TEEPO-glucose and TEMPO-glucose, potential contrast agents for MRI
Authors: Soikkeli M. , Sievänen K. , Peltonen J. , Kaasalainen T. , Timonen M. , Heinonen P. , Rönkkö S. , Lehto V.-P. , Kavakka J. S. , Heikkinen S.
Published: January 2015

Two organic radical contrast agents, TEMPO-Glc and TEEPO-Glc, were synthesized and their stabilities and contrast enhancing properties were tested with in vitro NMR and MRI experiments.
Toughened bio-based epoxy blend network modified with transesterified epoxidized soybean oil: synthesis and characterization
Authors: Sahoo Sushanta K. , Mohanty Smita , Nayak Sanjay K.
Published: January 2015

Novel bioresin epoxy methyl soyate was synthesized by transesterification process and subsequently used as reactive diluent for toughening of epoxy.
Fabrication of Au–AlAu4–Al2O3 superhydrophobic surface and its corrosion resistance
Authors: Cheng Yuanyuan , Lu Shixiang , Xu Wenguo , Wen Huidong
Published: January 2015

A stable superhydrophobic surface with excellent corrosion resistance has been fabricated via immersion and annealing without organic modification.
A combination of trimethylsilyl chloride and hydrous natural montmorillonite clay: an efficient solid acid catalyst for the azidation of benzylic and allylic alcohols with trimethylsilyl azide
Authors: Tandiary Michael A. , Masui Yoichi , Onaka Makoto
Published: January 2015

We present a new procedure to convert in situ natural montmorillonite clay into a partially acidified one using a catalytic amount of trimethylsilyl chloride and trace water.
Antimony tin oxide porous layers improve the poly(3,4-ethylenedioxythiophene) counter electrode fabricated by vapor deposition for dye-sensitized solar cells
Authors: Xia Xiang , Wu Wenyi , Ma Jiahui , Liu Tingting , Fei Dehou , Liu Xizhe , Gao Chunxiao
Published: January 2015

Antimony tin oxide supporting layer enhances the performance of the vapor deposited PEDOT electrode for dye-sensitized solar cells.
Preparation of CO2-philic polymeric membranes by blending poly(ether-b-amide-6) and PEG/PPG-containing copolymer
Authors: Khosravi Tayebeh , Omidkhah Mohammadreza
Published: January 2015

Membranes from the block copolymer poly(ether-b-amide-6) (Pebax® MH 1657) and its blends with PEG-block-PPG-block-PEG and PEG-ran-PPG copolymers were prepared, combining the beneficial properties of PEG (high selectivity) with those of PPG (high permeability, amorphous).
Application of electrodialysis to remove copper and cyanide from simulated and real gold mine effluents
Authors: Zheng Yun , Gao Xueli , Wang Xinyan , Li Zhaokui , Wang Yuhong , Gao Congjie
Published: January 2015

In this study, a laboratory-scale electrodialysis (ED) system with an effective area of 88 cm2 was used to remove copper and cyanide in simulated and real gold mine effluents.
Process optimization by response surface methodology for transesterification of renewable ethyl acetate to butyl acetate biofuel additive over borated USY zeolite
Authors: Nandiwale Kakasaheb Y. , Galande Nitish D. , Bokade Vijay V.
Published: January 2015

Response surface methodology revealed that 4% (w/w) B–USY zeolite is a stable (reusable for 6 cycles) and potential catalyst with a 96% yield of butyl acetate.
Triazolium based ionic liquid crystals: effect of asymmetric substitution
Authors: Stappert K. , Mudring A.-V.
Published: January 2015

A new series of asymmetrical 1-dodecyl-3-alkyl-triazolium bromides has been synthesized to investigate the effect of asymmetric substitution on their phase behavior.
Nanocomposites of graphene oxide, Ag nanoparticles, and magnetic ferrite nanoparticles for elemental mercury (Hg0) removal
Authors: Liu Yuxi , Tian Chong , Yan Bin , Lu Qingye , Xie Yijun , Chen Jian , Gupta Rajender , Xu Zhenghe , Kuznicki Steven M. , Liu Qingxia , Zeng Hongbo
Published: January 2015

Novel nanocomposites of graphene oxide, Ag nanoparticles, and magnetic ferrite nanoparticles for elemental mercury (Hg0) removal from combustion gases.
Biorecognition and highly sensitive determination of Ribonuclease A with chemiluminescence sensor based on Fe3O4/multi-walled carbon nanotubes/SiO2-surface molecular imprinting polymer
Authors: Duan Huimin , Li Leilei , Wang Xiaojiao , Wang Yanhui , Li Jianbo , Luo Chuannan
Published: January 2015

A new functional material Fe3O4/MWCNTs/SiO2 was used as a supporting material to prepare SMIP for the CL determination of RNase A.
Synthesis of hybrid silica nanoparticles grafted with thermoresponsive poly(ethylene glycol) methyl ether methacrylate via AGET-ATRP
Authors: Du Zhiping , Sun Xiaofeng , Tai Xiumei , Wang Guoyong , Liu Xiaoying
Published: January 2015

This emulsification–demulsification inversion related to the temperature-responsive surface chemistry could in future be exploited for separation and recycling of catalysts.
A rationally designed small molecule for identifying an in vivo link between metal–amyloid-β complexes and the pathogenesis of Alzheimer's disease
Authors: Beck Michael W. , Oh Shin Bi , Kerr Richard A. , Lee Hyuck Jin , Kim So Hee , Kim Sujeong , Jang Milim , Ruotolo Brandon T. , Lee Joo-Yong , Lim Mi Hee
Published: January 2015

An in vivo chemical tool designed to target metal−Aβ complexes and modulate their activity was applied to the 5XFAD mouse model of Alzheimer’s disease (AD) demonstrating the involvement of metal−Aβ in AD pathology.
Synthesis of core–shell α-Fe2O3@NiO nanofibers with hollow structures and their enhanced HCHO sensing properties
Authors: Cao Jing , Wang Ziying , Wang Rui , Liu Sen , Fei Teng , Wang Lijie , Zhang Tong
Published: January 2015

Core–shell α-Fe2O3@NiO nanofibers with hollow nanostructures are synthesized by a facile coaxial electrospinning method and calcination procedure and present enhanced HCHO gas sensing performances.
Chemically fixed autologous feeder cell-derived niche for human induced pluripotent stem cell culture
Authors: Joddar Binata , Nishioka Chieko , Takahashi Eiki , Ito Yoshihiro
Published: January 2015

A newer method of hiPS culture on feeder cell-derived niche is reported in this study.
Fluorescence imaging of interscapular brown adipose tissue in living mice
Authors: Rice Douglas R. , White Alexander G. , Leevy W. Matthew , Smith Bradley D.
Published: January 2015

Non-invasive optical imaging of interscapular BAT in mice using a micellar formulation of deep-red fluorescent probe, SRFluor680.
Electrical control of carriers' spin orientation in the FeVTiSi Heusler alloy
Authors: Zhang Jiahui , Li Xingxing , Yang Jinlong
Published: January 2015

Control of the spin-polarization direction by carrier doping in a quaternary Heusler alloy FeVTiSi with a bipolar magnetic semiconducting character and room temperature ferromagnetism.
Patterning of rubrene thin-film transistors based on electron irradiation of a polystyrene dielectric layer
Authors: Kim Jae Joon , Lee Hyeok Moo , Park Ji Won , Cho Sung Oh
Published: January 2015

An unprecedented approach to pattern rubrene TFTs is presented by combining an abrupt heating method with selective electron irradiation of polystyrene dielectric layers. The patterned rubrene TFTs exhibited good performances with charge mobilities of ∼1.3 cm2V−1s−1and on/off ratios higher than 108.
Phenothiazine modified triphenylacrylonitrile derivates: AIE and mechanochromism tuned by molecular conformation
Authors: Zhang Gonghe , Sun Jingbo , Xue Pengchong , Zhang Zhenqi , Gong Peng , Peng Jiang , Lu Ran
Published: January 2015

The substituted position in phenothiazine can tune the mechanochromic and AIE properties of phenothiazine modified triphenylacrylonitrile derivates.
Effects of benzo[a]pyrene on mouse germ cells: heritable DNA mutation, testicular cell hypomethylation and their interaction with nucleotide excision repair
Authors: Godschalk Roger W. L. , Verhofstad Nicole , Verheijen Marcha , Yauk Carole Lyn , Linschooten Joost O. , van Steeg Harry , van Oostrom Conny T. , van Benthem Jan , van Schooten Frederik J.
Published: January 2015

Benzo[a]pyrene induces heritable mutations in male germ cells.
Diastereoselective synthesis of O symmetric heterometallic cubic cages
Authors: Yang Yang , Jia Jian-Hua , Pei Xiao-Li , Zheng Hao , Nan Zi-Ang , Wang Quan-Ming
Published: January 2015

Enantiopure chiral cubic cages have been diastereoselectively synthesized, showing CD enhancement as a result of configuration rigidity.
Lewis acidity enhancement of triarylborane by appended phosphine oxide groups
Authors: Kwak Jaewoo , Van Nghia Nguyen , Lee Junseong , Kim Hyoseok , Park Myung Hwan , Lee Min Hyung
Published: January 2015

Introduction of a phosphine oxide group into a triarylborane significantly enhances the Lewis acidity of the boron center, the extent of which increases additively with the number of phosphine oxide groups.
Regioselective synthesis of highly functionalized alkenylboronates by Cu-catalyzed borylation of propargylic silylalkynes
Authors: Kim Yeong Eun , Li DingXi , Yun Jaesook
Published: January 2015

High regioselectivity was achieved in the Cu(i)-catalyzed borylation of internal propargylic alkynes with a silyl substituent to afford multifunctionalized alkenylboron compounds.
Controllable synthesis and change of emission color from green to orange of ZnO quantum dots using different solvents
Authors: Liu Xu , Xing Xinxin , Li Yuxiu , Chen Nan , Djerdj Igor , Wang Yude
Published: January 2015

ZnO quantum dots, a few nanometers in size, exhibited strong visible emission from green to orange, resulting from the quantum size effect and the change in defect concentration due to the different solvents used for preparation.
Novel nitrogen precursors for electrochemically driven doping of titania nanotubes exhibiting enhanced photoactivity
Authors: Siuzdak Katarzyna , Szkoda Mariusz , Sawczak Mirosław , Lisowska-Oleksiak Anna
Published: January 2015

A simple electrochemical method was elaborated for the modification of titania nanotubes with nitrogen atoms using different dopant precursors.
A reduction-dissociable PEG-b-PGAH-b-PEI triblock copolymer as a vehicle for targeted co-delivery of doxorubicin and P-gp siRNA
Authors: Xu Minghui , Qian Junmin , Suo Aili , Liu Ting , Liu Xuefeng , Wang Hongjie
Published: January 2015

The formation and drug release by dissociation in the tumor microenvironment of PEG-b-PGAH-b-PEI triblock copolymeric nanomicelleplexes.
PTC MWCNT/DI-water switchable composites
Authors: Sun Pengcheng , Huang Yun , Yang Jun , Cheng Guoan , Zheng Ruiting
Published: January 2015

In this paper, we study the electrical and thermal conductivities of multi-walled carbon nanotube (MWCNT)/DI-water composites via first order phase transition. Around 0 °C, the contrast ratio of electrical and thermal conductivities reaches 1250 and 3.58 times, with PTC and NTC effects respectively.
Co-delivery of doxorubicin and P-glycoprotein siRNA by multifunctional triblock copolymers for enhanced anticancer efficacy in breast cancer cells
Authors: Xu Minghui , Qian Junmin , Suo Aili , Cui Ning , Yao Yu , Xu Weijun , Liu Ting , Wang Hongjie
Published: January 2015

The triblock copolymers can chemically conjugate DOX and simultaneously complex siRNA to form nanocomplexes exhibiting reduction- and pH-triggered release behaviors.
Photoluminescence and Raman mapping characterization of WS2 monolayers prepared using top-down and bottom-up methods
Authors: Wang X. H. , Ning J. Q. , Zheng C. C. , Zhu B. R. , Xie L. , Wu H. S. , Xu S. J.
Published: January 2015

Two kinds of tungsten disulfide (WS2) monolayers, respectively prepared using top-down and bottom-up approaches, were studied with Raman and photoluminescence (PL) mapping techniques.