bluuebunny/crossref_metadata_2025 huggingface dataset:
Students’ Satisfaction Towards Online Learning at English Education Study Program
Authors: Jeremias Benjamin , Rijoly Helena Magdalena , Binnendyk Sophia
Published: September 2023

This study aims to explore students’ satisfaction during online learning process related to 3 aspects which are: Course Structure, Online Learning Flexibility and Technology Quality in English Education Study Program of Pattimura University. This study was conducted with Mixed Method research design using questionnaire as the data collection technique. There were 2 types of questionnaires: Close-Ended Likert Scale questionnaires and Open-Ended Questionnaires. The participants were the active students of English Education Study Program of Pattimura University batch 2017, 2018, 2019 and 2020. The result shows that students’ satisfaction rate is between Satisfied and Satisfied Enough. This means that the satisfaction rate is average. The study also produces a collection of students’ feedbacks and suggestion.
The Use of The Word Splash Strategy in Vocabulary Enhancement at Junior High School Level
Authors: De Queljoe Gabriela Elizabeth , Nikijuluw Renata C. G. V. , Satumalay Smarty Jabez Samuel
Published: September 2023

This paper explores using the word splash strategy to enhance vocabulary at the Junior High School Level. Some researchers have applied the word splash strategy to help students learn vocabulary. The research showed that by using the word splash strategy, students could effectively motivate learning vocabulary. Students showed evidence of learning by using the word splash strategy. Word Splash is a learning strategy that stimulates thinking around a topic. The Word Splash Strategy allows students to learn new words and ideas before they start reading and helps them figure out how the word might relate. This strategy can help students improve their vocabulary by allowing them to predict words before they read the passage and connect new words or ideas to the passage's main idea.
OPTIMALISASI PENGELOLAAN WILAYAH PESISIR SECARA TERPADU DALAM MEMAJUKAN OBJEK PARIWISATA DI NEGERI SULI KECAMATAN SALAHUTU KABUPATEN MALUKU TENGAH
Authors: Sahetapy Petronela
Published: September 2023

Tema senteral penelitian ini mengarah pada optimalisasi pengelolaan wilayah pesisir secara terpadu dalam memajukan objek pariwisata di Negeri Suli Kecamatan Salahutu Kabupaten Maluku Tengah, yang mana terfokus pada masalah yang dihadapi bahwa belum optimal pengelolaan wilayah pesisir secara terpadu dalam memajukan objek pariwisata yang tampak dari sarana dan prasarana serta fasilitas pendukung yang belum memadai, yakni selama ini pengelolaannya belum sesuai dengan apa yang diharapkan. Sebagai penelitian yang bersifat deskriptif dengan jumlah sampel sebanyak 22 orang, Disamping teknik analisis data dilakukan secara kuantitatif dan akan dideskripsikan dengan bantuan tabel frekuensi dan kriteria interprestasi skor persentase maupun dukungan kategori penilaian untuk mengetahui besar kecilnya dukungan responden dan nilai yang diperoleh dan secara terakumulasi nilai skor yang diperoleh dalam perhitungan persentase dan inerpretasinya tetap mengacu pada kesesuaiannya dengan kriteria interprestasi skor. Besaran nilai CRR/SA dan Nilai ISP bersifat relatif searah sesuai dengan peluang penetapan prioritas, yang dimulai dari nilai ISP yang terendah secara berurutan ke nilai ISP yang tertinggi untuk dilakukan peningkatan dan penguatan dalam optimalisasi hasilnya yakni, merencanakan diprioritaskan pertama, dan mengorganisir dipriortaskan ke dua, sementara menggerakan dan mengawasi diprioritaskan secara bersamaan sebagai prioritas ketiga dan diharapkan dalam tindak lanjutnya dapat terlaksana dengan baik guna pengembangan pariwisata di Negeri Suli Kecamatan Salahutu Kabupaten Maluku Tengah.
Pelatihan Desain Grafis Berbasis Vektor Untuk Meningkatkan Minat Usaha.
Authors: Purnomo Nanto , Nawafilah Nur Qomariyah , Husen Husen
Published: September 2023

Abstrak: Desain grafis adalah suatu media untuk menyampaikan informasi melalui bahasa komunikasi visual dalam wujud dwimatra ataupun trimatra yang melibatkan kaidah-kaidah estetik.  Dilihat dari analisa situasi masalah mitra dapat diidentifikasi sebagai berikut: pertama, kurangnya pengetahuan dari peserta pelatihan mengenai desain grafis. Kedua, terdapat minat peserta yang ingin mengetahui tentang verkor art. Ketiga, terdapat peluang usaha desain grafis terutama vektor art bagi peserta. Tujuan dan manfaat kegiatan pengabdian masyarakat ini adalah sebagai berikut: pertama, kegiatan ini sebagai salah satu bentuk transfer ilmu pengetahuan tentang desaint grafis vector art. Kedua, peserta diharapkan dapat mengasah kreatifitas masing-masing. Ketiga , melihat peluang usaha yang ada peserta diharapkan timbulnya keinginan atau  minat usaha dalam bidang vektor art yang dapat ditekuni.Dari keseluruhan pelaksanaan pelatihan menunjukan hasil yang positif meningkatkan keterampilan, wawasan dan minat usaha peserta terhadap bidang desain grafis..Kata Kunci: Desain Grafis, Vektor Art, dan Minat Usaha Abstract: Graphic design is a medium for conveying information through the language of visual communication in a two-dimensional or three-dimensional form that involves aesthetic principles. Judging from the analysis of the partner's problem situation, the following can be identified: first, the lack of knowledge of the training participants regarding graphic design. Second, there was an interest in the participants wanting to know about verkor art. Third, there are graphic design business opportunities, especially vector art for participants. The goals and benefits of this community service activity are as follows: first, this activity is a form of knowledge transfer about vector art graphic design. Second, participants are expected to be able to hone their own creativity. Third, seeing the business opportunities available to the participants, it is hoped that there will be a desire or business interest in the vector art field that can be pursued. The overall implementation of the training shows positive results in increasing the participants' skills, insight and business interest in the field of graphic design.Keywords: Graphic Design, Vector Art, and Business Interest
Penanganan perdarahan post partum (haemorhagi post partum/ HPP)
Authors: Gondo Harry Kurniawan
Published: September 2023

Perdarahan Postpartum dini oleh karena atonia uteri merupakan salah satu tiga penyebab terbesar kematian maternal di negara berkembang
MTM in Motion – Perspectives to Digital Work Design
Authors: Kuhlang Peter , Benter Martin , Neumann Maria
Published: September 2023

The cost of production is a key factor for industrial companies. Labour costs are one relevant portion of these costs, especially for production sites with a high percentage of manual processes. Therefore, describing, analysing, and designing manual work processes in a systematic way is an important task in most Industrial Engineering departments. There are multiple methods to describe and analyse work processes. Widely known methods include REFA, MTM and Work Factor. While there are multiple MTM methods to address the different types of production, one of the most established methods is MTM-UAS®. The most recent process building block system is MTM-HWD®. It describes work processes not only from a productive standpoint, but also includes ergonomic factors to assure productive and ergonomic work in one step. While the MTM systems can be used to systematically design work processes, they still require manual effort for data collection and interpretation. Due to this fact, not every company has the necessary. One possibility to reduce this effort is the automatic interpretation of digitized human motion data. Motion data depicts human movements and postures and includes, for example, distances covered, joint positions or object interactions. One technology that is capable to generate this data is virtual reality. Thanks to the advances in the technology in recent years, it can be used in a variety of workplaces and with minimal training. This article presents an approach how one can use the motion data of virtual reality tools to derive automated MTM-UAS® and MTM-HWD® analyses. Using VR technology thus reduces the analysis effort significantly and offers to expand the areas of application beyond its traditional domain. First, the article shows a workplace example that was modelled using a virtual reality tool. It then explains the necessary data to automatically derive MTM-analyses. It then shows the translation into a valid MTM-analyses. The article concludes with a critical discussion and an outlook on how this approach can be transferred to other digital technologies. With such a transfer it is conceivable to design a higher number of workplaces in a productive and ergonomic way.
Lessons learned from the 2022 CONVERSE Monogenetic Volcanism Response Scenario Exercise
Authors: Lin Yolanda C. , Lev Einat , Mukerji Ria , Fischer Tobias P. , Connor Charles , Stovall Wendy , Poland Michael P. , Iezzi Alexandra M. , Wauthier Christelle , Gonzalez-Santana Judit , Wright Heather , Wolf Samantha , Kasali Tobi
Published: September 2023

When volcanic unrest occurs, the scientific community can advance fundamental understanding of volcanic systems, but only with coordination before, during, and after the event across academic and governmental agencies. To develop a coordinated response plan, the Community Network for Volcanic Eruption Response (CONVERSE) orchestrated a scenario exercise centered around a hypothetical volcanic crisis in Arizona’s San Francisco Volcanic Field (SFVF). The exercise ran virtually from February 4 to March 4, 2022. Over 60 scientists from both academic and governmental spheres participated. The scenario exercise was assessed for its effectiveness in supporting collaborative production of knowledge, catalyzing transdisciplinary collaboration, supporting researcher confidence, and fostering a culture of inclusion within the volcanology community. This identified a need to support early career researchers through community and allyship. Overall, the 2022 CONVERSE exercise demonstrated how a fully remote, extended scenario can be authentically implemented and help broaden participation within the volcano science community.
STUDY OF THE CONDITIONS OF RIVERBED FORMATION OF THE PEREDKARPATTIA RIVERS WITHIN THE ALLUVIAL PLAINS
Authors: Palanychko Olha
Published: September 2023

The article reveals the results of the study of the main factors of river riverbed formation within the foothills.Based on the results of previous studies, archival materials and own works, the effect of the main factors of channel formation was investigated according to the author's functional-basin scheme for the conditions of alluvial plains. The territory of Peredkarpathia and the adjacent parts of the Carpathians and Podillia, which are characterized by extended areas of river valley bottoms filled with alluvium (alluvial plains), were chosen for the study. The artificial limitation of the research area is the state border of Ukraine. The selected territory of the study was tentatively called the hydrological and riverbed science Peredkarpathia, but it goes beyond the geomorphological Peredkarpathia
It is proposed to study the features of riverbed formation conditions of the main watercourses within the study area (alluvial plains) in stages. The author singled out four levels of research detailing, each of which has a corresponding plan (research algorithm). At the first (highest) level of consideration, an overview map of alluvial plains was drawn up, showing alluvial plains within the study area against the background of the general structure of the territory, the main orotectonic structures. On the second, survey maps of the alluvial plains of the first order were created. They show the main alluvial plains of the region as river-valley systems associated with negative orotectonic structures and adjacent formations. At the third level of consideration, we compiled survey and analytical maps of second-order alluvial plains. Here are shown the extended areas of the bottom of the valleys of the main rivers within the alluvial plains of the first order. The maps also show the main features of the internal relief of the bottom of the valleys; hydrographic grid; generalized boundaries of multi-year riverbed formation bands, floodplains and boundaries of homogeneous sections of riverbeds and floodplains. One hundred homogeneous sections of riverbeds and floodplains on 18 main rivers were identified within the study area, and a description of their sequence along the rivers within the alluvial plains was also made. At the fourth stage, we selected analytical maps of parts of the alluvial plains of the second order. They reflect the details of the topography of the bottom of river valleys (as well as the hydrographic grid as an indicator of the structure of the bottom), the presence of bedrock outcrops for the analysis of local conditions of the development of the stream-channel system.
Keywords. geohydromorphological analysis; riverbed processes; alluvial plains; homogeneous areas; riverbed-forming flows.
Manajemen Tenaga Pendidik di MI Darussalam 01 Kartasura
Authors: Eka Saputra Dimas Maulana , Mahiri Suci Az-Zahro Nadalina , Puji Lestari Trianti , Nur Dewanti Oktaviana
Published: September 2023

Tujuan dari penelitian ini antara lain untuk mengetahui proses rekrutmen seleksi pendidik dan tenaga kependidikan serta penentuan penempatan tenaga kerja di MI Darussalam 1 Surakarta. Penelitian ini menggunakan pendekatan kualitatif agar hasil dari kajian atas suatu fenomena yang diteliti menjadi lebih komprehensif. Melalui pendekatan kualitatif metode yang digunakan dalam penelitian ini menggunakan data deskriptif yaitu bahasa tertulis atau lisan dari orang dan pelaku yang dapat diamati. Pengumpulan data yang digunakan yaitu dengan wawancara, observasi, dan dokumentasi. Tempat yang dipilih untuk observasi dan wawancara adalah MI Darussalam 01 Kartasura. Wawancara yang dilakukan yaitu pada bulan Oktober 2022. Hasil penelitian ini menunjukkan bahwa (1) Rekrutmen yang dilakukan di Sekolah MI Darussalam 1 Surakarta dilaksanakan setiap tahun. Baik itu bertujuan untuk mencari guru baru dengan jabatan atau jabatan yang lowong atau jabatan tambahan. (2) Seleksi dilaksanakan di Sekolah MI Darussalam 1 Surakarta dilakukan setelah rekrutmen dengan tujuan untuk menentukan kriteria calon pendidik/guru sesuai kebutuhan lembaga. Ketika rekrutmen telah dilakukan, pelamar kemudian akan melewati tahap seleksi. (3) Salah satu cara untuk meningkatkan mutu pendidikan di Sekolah MI Darussalam 1 Surakarta adalah melalui proses rekrutmen dan seleksi yang baik. Antara lain dengan menyeleksi produk unggulan melalui rekrutmen dan seleksi guru yang selektif atau ketat yang bertujuan untuk menghasilkan produk unggulan yang berkualitas
Manajemen Sarana Dan Prasana Pendidikan Perspektif Ayat-Ayat Al-Qur’an
Authors: Rohmansyah Moh Suhri , Firdaos Rijal
Published: September 2023

Artikel ini membahas manajemen sarana dan prasarana pendidikan dalam perspektif ayat-ayat al-quran. Pembahasan sarana dan prasana pendidikan ini penting diuraikan karena manajemen pendidikan merupakan komponen-komponen yang saling terkait diantaranya kurikulum, materi, metode, pendidik, peserta didik, sarana prasarana, dan komponenlainya. Selama ini pemahaman pemahaman sarana dan prasaran sebagai komponen yang sangat berpengaruh dalam pendidikan masih kurang, sehingga proses pembelajaran menjadi kurang maksimal. Kajian ini menggunakan metode penelitian pustaka dengan pendekatan analisis-deskriptif. Hasil dari kajian ini menunjukkan bahwa manajemen sarana dan prasarana pendidikan ialah proses pengelolaan dan pemanfaatan semua sarana dan prasarana pendidikan secara efektif. Pentingnya pengelolaan sarana prasarana pendidikan diperkuat dengan pandangan-pandangan yang berlandaskan ayat-ayat al-qur’an. Adapun tujuan dari manajemen sarana dan prasarana pendidikan ini yaitu lembaga pendidikan mampu memberikan layanan secara profesional sehingga proses pembelajaran bisa berlangsung secara efektif dan efisien. pelaksanaan manajemen sarana dan prasarana pendidikan meliputi (1) Perencanaan sarana dan prasarana pendidikan (2) pengorganisaian sarana dan prasarana pendidikan (3) pelaksanaan dan pendayagunaan sarana dan prasarana pendidikan (4) Inventarisasi sarana dan prasarana pendidikan (5) Pengawasan dan pemeliharaan sarana dan prasarana pendidikan. Kesimpulan dari kajian ini adalah manajemen sarana dan prasarana pendidikan harus berorientasi kepada prinsip untuk menjadikan kegiatan pembelajaran di lembaga pendidikan dapat berjalan dengan efektif dan efesien.
Google Formulir Sebagai Alternatif Media Evaluasi Pembelajaran Bahasa Arab Pada Masa Pandemi Covid-19
Authors: Nurhaliza Annisa , Sudjani Desky Halim , Maryani Novi
Published: September 2023

Pandemi Covid-19 mengalihkan kegiatan belajar dan mengajar yang semula dilaksanakan di dalam kelas dengan bertatapan secara langsung menjadi pembelajaran dengan bantuan sistem jaringan yang terintegrasi dengan teknologi dan dilaksanakan di rumah. Seiring dengan pelaksanaan pembelajaran secara virtual ini, pemerintah dan sekolah tetap berupaya untuk meningkatkan kualitas pendidikan pada masa pandemi Covid-19.  Salah satu alternatif dalam proses evaluasi pembelajaran adalah dengan bantuan media evaluasi pembelajaran Google Formulir yang merupakan fitur gratis dari Google Docs dan mudah dikases oleh semua kalangan. Objek penelitian bertempat di MAN 2 Cianjur dengan populasi kelas XI berjumlah 165 peserta didik, pengambilan sampel adalah 50% dari jumlah peserta didik yaitu 83 peserta didik sebagai fokus penelitian. Adapun teknik pengambilan sampel dengan menggunakan teknik Simple Random Sampling. Jenis penelitian yang digunakan adalah korelasi fungsional yang bertujuan mencari pengaruh antara variabel bebas terhadap variabel terikat, sedangkan data diperoleh melalui observasi, wawancara, dokumentasi dan kuesioner. Hasil penelitian menunjukan bahwa Google Formulir memiliki pengaruh sebesar 4.7% terhadap hasil belajar dan data hasil observasi menunjukan ketertarikan responden terhadap Google Formulir yaitu Kemampuan mengoperasikan/ menggunakan media 67.8%, Suka dengan penggunaan Google Formulir 58.6%, efisiensi waktu 58.6%, mudah dimengerti 48.3%, mudah diakses 60.9%, dan menghemat penggunaan kertas 58.6%. Adapun hasil analisis uji hipotesis menunjukan nilai 2,001>1,989 yang berarti H0 diterima dan Ha ditolak. Artinya tidak terdapat pengaruh yang signifikan antara variabel media evaluasi pembelajaran Google Formulir dengan hasil belajar bahasa Arab peserta didik.
Introducing and Evaluating the Operational Performance of a New Interchange Design: The Continuous Green-T Median U-Turn Interchange
Authors: Alzoubaidi Mutasem , Alzoubaidi Amr , Zlatkovic Milan
Published: September 2023

This study proposes a new design called the continuous green-T median U-turn (CGT-MUT) interchange and evaluates its operational performance compared to three interchanges. The selected interchanges for comparison are the Superstreet, Single Point Diamond Interchange (SPDI), and the Synchronized interchange. The evaluation is based on a microsimulation environment created in VISSIM combined with ASC/3 Software-in-the-Loop signal controllers. The findings show that the CGT-MUT enhanced the network-wide and intersection-level operations regarding various measures of effectiveness. Additionally, while the CGT-MUT did not always outperform all the other designs in terms of the on-ramp turning traffic travel times, it outperformed the Superstreet and Synchronized in terms of the off-ramp turning traffic travel times and resulted in the least through traffic travel times for all the tested scenarios. Particularly, the CGT-MUT’s through travel times were 9% – 30%, 26% – 42%, and 13% – 38% less than those for the Superstreet, SPDI, and Synchronized interchanges, respectively.
EETS, REETS, OPEN BALKANS: Concepts, Regulations, Practical Examples
Authors: Šaponjić Dušan , Glavic Drazenko
Published: September 2023

This paper presents the theoretical and legal framework, along with examples of the EETS and REETS toll collection systems. Within the definition of the legal framework, Directive 2019/520 of the European Commission is presented, outlining the processes that a toll collection system must undergo to successfully implement interoperability. Additionally, this paper showcases various practical examples of how European Union member states and those outside it have implemented the REETS project within their respective regions. The most notable case of the REETS is the "Open Balkans." The aim of this paper is to inform the professional in road sector about current developments in toll collection in Europe, the Balkans, and Serbia through a review of literature and practical informations.
Environmental protection and the road database
Authors: Dragović Nada , Radulović Jevremović Snežana , Jeličić Mimoza
Published: September 2023

In recent years, we have witnessed the intensive construction of road routes through Serbia. Mitigation plans have been designed on all newly constructed sections and environmental monitoring is foreseen. In order to successfully implement mitigation and monitoring plans, there is a need to consolidate a large number and type of data. Within the PE "Roads of Serbia" there is a Database department responsible for the management, collection, updating and analysis of the data referring to roads, traffic, traffic signage and equipment, traffic accidents, structures, etc. This paper points to the necessity of upgrading the existing database with data based on applied environmental protection measures, requirements regarding regular maintenance and monitoring of their effectiveness through a monitoring plan. All the elements of mitigation plans that should be included in the database are presented in detail: noise protection walls, oil separators used to treat waste water, wire fences that are adapted to certain animal species and wildlife crossings. The database should also contain monitoring data for surface water, groundwater, air, soil and noise level. In order to improve environmental protection, proposals were also made on the use of data already entered in the existing database and their upgrading.
The Preferences That Reflect al-Zamakhsharī's Mu‘tazilite Thought in al-Kashshāf: A Survey in the Context of the Theory of Luṭf
Authors: BOŞNAK Muhammed , BOŞNAK Nagihan Ayşe
Published: September 2023

Luṭf, which means delicacy, elegance, and favor in dictionary, as a concept, refers to God's di-recting his servants to faith and preventing them from committing sins. In general, the theory of luṭf, which was founded on the principle of ‘adl (justice) and moderation of the theory of aṣlaḥ (the optimal), was understood by the Mu'tazilites of Basra as making certain actions obligatory for Allah, and from this aspect, it caused controversies. These discussions were also reflected in the interpretation of the Qur’ān, and the verses were interpreted by Mu‘tazila to form a basis for the theory of luṭf. al-Zamakhsharī (d. 538/1144), who is a member of the Basra school of Mu‘tazila, defends the theses of his denomination in a scattered manner in al-Kashshāf. This situation, which appears between the lines, is known as the general feature of his tafsīr. This knowledge we have about the work in general needs to be confirmed through various examples. This study, prepared for this purpose, reveals how much the Mu‘tazilite aspect is reflected in his tafsīr, based on his ideas about luṭf in al-Kashshāf. As a matter of fact, while interpreting the verses about luṭf, he constantly emphasizes Mu‘tazilite principles and objects to opposing ideas through Mu‘tazilite arguments. In this respect, we can say that he acted like a Mu‘tazilite theolo-gian on the subject of luṭf. Our study aims to contribute to filling the gap in the literature by re-vealing this situation. In this regard, our research is limited to reading al-Kashshāf through the kalām literature within the framework of the theory of luṭf. Therefore, we will not go into the details of other theological issues, and our references to tafsīr works other than al-Kashshāf will be limited. Thus, theological background of al-Kashshāf will be scrutinized on one subject and this study will constitute a reference point for its denominational aspect.
ULBP2 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that UL16-binding protein 2, encoded by ULBP2, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. ULBP2 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of ULBP2 in primary tumors was correlated with overall, distant metastasis-free and recurrence-free survival. Modulation of ULBP2 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Enhancing Cloud ERP Security with AI: A Review
Authors: Mills Michael
Published: September 2023

Cloud-based enterprise resource planning (ERP) systems contain valuable organizational data that faces various cybersecurity threats. Artificial intelligence (AI) technologies like machine learning, natural language processing, and predictive analytics can significantly improve security for cloud ERP platforms. This paper reviews the risks cloud ERP systems face, core capabilities where AI enhances security, real-world examples of AI in action, and key technologies powering AI-driven security. Challenges in deploying AI for cloud ERP security are also analyzed. The review concludes that AI solutions add efficiency, automation, and intelligence to ERP security operations. However, the performance of AI systems needs continuous monitoring and enhancement.
USP39 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that ubiquitin specific peptidase 39, encoded by USP39, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. USP39 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of USP39 in primary tumors was correlated with overall, distant metastasis-free and recurrence-free survival. Modulation of USP39 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Determining the Feasibility, Face Validity, and Design Features for the Remote Adult Language Experiment Tool
Authors: Lancaster Hope Sparks , Haschenburger Mia , Parks Ryan M.;Ryan.Parks@boystown.org , Bashford Seth , Fitzpatrick Denis , Buttner Alicia
Published: September 2023

We describe the first stages of development of the Remote Adult Language Experiment (ReAL-E), an internet-based toolbox for gathering data on the native spoken language performance of adults. The purpose of these studies was to establish face validity of the internet-based tasks and solicit shareholder feedback on important design features. We describe how we developed the internet-based tasks and novel items. In Study 1, content experts rated the face validity of the tasks and provided feedback on the adaptations. We implemented their suggestions. In Study 2, we engaged in user-experience testing. We examined face validity by assessing user performance on the updated tasks to determine if performance aligned with past research. Users provided feedback in semi-structured interviews. The results of these two studies provide evidence for feasibility and face validity of the tool. We have also identified important design features we are continuing to work towards implementing.
GAP43 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that growth-associated protein 43, encoded by GAP43, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. GAP43 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of GAP43 in primary tumors was correlated with patient recurrence-free survival. Modulation of GAP43 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
EGLN3 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that egl-9 family hypoxia-inducible factor 3, encoded by EGLN3, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. EGLN3 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of EGLN3 in primary tumors was not correlated with patient survival outcomes in human breast cancer. Modulation of EGLN3 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Spreading like wildfire: The securitization of the Amazon rainforest fires on Twitter
Authors: Umansky Natalia
Published: September 2023

As a tool of political communication and information diffusion, social media has transformed the process of securitization, allowing (in)security messages to spread and scale up rapidly. Focusing on the case of the Amazon rainforest fires in 2019, this chapter seeks to answer two questions: How does securitization spread in online networks? And who are the actors that contribute to the diffusion of security messages? To explore this puzzle, the chapter develops a dictionary of query terms and performs a full-archive search to collect tweets posted between June and October 2019 and reconstruct the communication network of over three million users. Drawing from theories of online activism and research on information diffusion in networks, the study uses both the structure of the Twitter network and the dynamics of activity in message exchange to identify four types of users and explore their roles in the spread of the message. The findings shed new light on the ways in which social media facilitates the definition of security problems and provide empirical evidence of the prominent position of influence taken by lay actors in the process of securitization.
MROH6 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that maestro heat-like repeat family member 6, encoded by MROH6, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. MROH6 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of MROH6 in primary tumors was correlated with patient recurrence-free survival. Modulation of MROH6 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Informing Conservation Techniques With Knowledge of Urban Evolution
Authors: Mittal Aniket
Published: September 2023

Since ancient times, humans have utilized information about nature to ensure the sustainment of biodiversity, both for humans and the species that live around us. For example, the Bengalese utilized knowledge of algal blooms to inform management that it breaks down contaminated water and reduces pollution in over 300 fish ponds (Watson). As nature becomes increasingly connected with urban cities, it begs the question, how can knowledge of urban evolution inform conservation and management strategies for biodiversity? In this review paper, we examine that very question. From our conclusions, we reason that while current conservation approaches consider cities as static—preserving existing urban structures and protecting current species—in order to reduce the impact on biodiversity from urban evolution, conservation practices must be dynamic—acknowledging urban evolution changes in the process with the adaptive reuse and conservation of features.
Côn trùng với vai trò thực phẩm: từ ta tới tây rồi lại về ta
Authors: Vuong Quan-Hoang
Published: September 2023

Với 9 tỷ cư dân Trái Đất vào năm 2030, đảm bảo protein là một công việc khó khăn. Đồng thời, việc chăn nuôi gia súc lấy thịt cũng trở nên thách thức do làm gia tăng khí nhà kính trong khí quyển. Do đó, gần đây, các thông tin quốc tế về ăn côn trùng như nguồn dinh dưỡng ngày càng nhiều hơn. Ăn côn trùng không lạ ở Việt Nam. Cà cuống hay bò cạp ngày nay là các món đặc sản, đắt tiền. Nhưng bình dân hơn như dế và châu chấu cũng không còn là món dễ kiếm nữa. Tuy vậy, ở bình diện quốc tế, ăn côn trùng là cả một mặt trận truyền thông, ở đó, thông tin đôi khi trái chiều và xu hướng ăn côn trùng như thực phẩm chưa hình thành.
MED19 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data ()4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that mediator complex subunit 19, encoded by MED19, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. MED19 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of MED19 in primary tumors was correlated with patient distant metastasis-free and recurrence-free survival. Modulation of MED19 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Climate Change and Health Transitions: Evidence From Antananarivo, Madagascar
Authors: Klein Jordan D. , Rasoanomenjanahary Anjarasoa
Published: September 2023

BACKGROUNDGlobal climate change poses grave risks to population health, especially in low and middle income countries (LMICs). It both threatens the sustainability of nascent epidemiological transitions and raises prospects for counter transitions driven by indirect climate impacts on mortality such as those from reemerging infectious diseases and by direct impacts of extreme climatic events.OBJECTIVEWe investigate how the relationship between climate and mortality has changed as Antananarivo, Madagascar progressed through the stages of the epidemiological transitionfocusing on enteric infection mortality in children under 5.METHODSUsing death registration, precipitation, and temperature time series data spanning over four decades we model the climate-cause-specific mortality relationships during each stage of the epidemiological transition using generalized additive models.CONCLUSIONSWhile we find that childhood enteric infection mortality has become less sensitive to low rainfall and higher temperatures, it has become more sensitive to heavy rainfall. Mortality from other causes has also become less sensitive to high temperatures but has become slightly more sensitive to heavy rainfall while significantly more sensitive to low temperatures.CONTRIBUTIONThis is the first multidecade climate-mortality study of a city in Sub-Saharan Africa outside of South Africa.
The roles of French community pharmacists in palliative home care
Authors: Cuchet Isabelle , Dambrun Michaël , Bedhomme Sabrina , Savanovitch Chantal , Vaillant-Roussel Hélène , lander van
Published: September 2023

The World Health Organization identifies pharmacists as a key resource in palliative care. However, the roles of these professionals in end-of-life care at home remain poorly understood, and community pharmacists themselves sometimes struggle to recognize their true role in this care. The aim of our study was to analyze community pharmacists’ representations of their roles in palliative care at home in France.The methodology was qualitative and based on semi-structured interviews with community pharmacists (n = 26). The interpretative phenomenological analysis approach was used. Lexicometric analysis of the verbatim was realized with Alceste software (IMAGE, CNRS, France).Three main elements of the community pharmacist’s role were identified: drug expertise, care management, and psychosocial support for patients and their families. The important psychosocial support provided by community pharmacists to their patients and/or their loved ones at the end of life, which has been little described until now, should be better recognized as it could have a positive impact on preserving the mental health of caregivers and on patient compliance.
WDR45B is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that WD repeat domain 45, encoded by WDR45B, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. WDR45B mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of WDR45B in primary tumors was correlated with patient distant metastasis-free and recurrence-free survival. Modulation of WDR45B expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
EME1 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that essential meiotic structure-specific endonuclease 1, encoded by EME1, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. EME1 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of EME1 in primary tumors was correlated with patient distant metastasis-free survival. Modulation of EME1 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Năng lượng hạt nhân: Tiềm năng và rủi ro trong bối cảnh biến đổi khí hậu
Authors: Phương L. V.
Published: September 2023

Cuộc tranh luận xung quanh việc sử dụng năng lượng hạt nhân đã là một vấn đề gây tranh cãi trong nhiều thập kỷ và tiếp tục gây chia rẽ ý kiến trên toàn cầu. Một mặt, những người ủng hộ cho rằng, năng lượng hạt nhân là nguồn năng lượng đáng tin cậy và có hàm lượng carbon thấp, có khả năng đáp ứng nhu cầu năng lượng ngày càng tăng của nhân loại, đồng thời giảm phát thải khí nhà kính. Mặt khác, những người phản đối nêu lên mối lo ngại về rủi ro an toàn, xử lý chất thải hạt nhân và khả năng xảy ra tai nạn thảm khốc. Bài viết này sẽ xem xét cả hai mặt của lập luận để xác định liệu chúng ta có nên giữ năng lượng hạt nhân như một phần trong cơ cấu năng lượng của mình hay không. (Tạp chí Kinh tế và Dự báo; ngày 25-9-2023)
“TRADE BARRIER” IS THE MAIN CHALLENGE FOR THE DILIRIZATION OF INDONESIAN MINING PRODUCTS
Authors: naryono endang
Published: September 2023

The most crucial challenge that Indonesia faces is the trade challenge created by other countries. Mining products, such as nickel, are often subject to anti-dumping and anti-subsidy measures by the European Union. The existence of Law no. 3 of 2020 concerning Amendments to Law No. 4 of 2009 concerning Mineral and Coal Mining mandates the sale of minerals abroad after three years of enactment or 2023. This policy aims to downstream so as to create added value while meeting domestic needs. The mining industry in Indonesia has great potential to be developed through the downstream process. The downstream process carried out in the last two years shows that mining has made a significant contribution to Indonesia's trade balance. This increase in downstream exports has helped create a trade balance and balance of payments surplus which has had a positive impact on the stability of the rupiah exchange rate and macroeconomic indicators. Apart from that, job creation has also increased significantly. "Especially in the Teluk Weda, Obi, Morowali and Konawe areas, where the number of workers reaches tens of thousands and the average salary is above the regional minimum wage. The government's target is to integrate downstreaming to an advanced stage in order to attract greater investment. However, the downstream process is not easy, in fact it faces various challenges that need to be resolved. Such as in the process of downstreaming the mining industry in Indonesia. One of the main challenges is the large investment required. On average, downstream projects in the mining industry have quite large costs, above US$ 1 billion.
POLR2G is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that RNA polymerase II subunit G, encoded by POLR2G, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. POLR2G mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of POLR2G in primary tumors was correlated with patient distant metastasis-free survival. Modulation of POLR2G expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
AKT1 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that AKT serine/threonine kinase 1, encoded by AKT1, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. AKT1 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of AKT1 in primary tumors was correlated with patient distant metastasis-free survival. Modulation of AKT1 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
POP1 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that POP1 homolog, ribonuclease P/MRP subunit, encoded by POP1, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. POP1 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of POP1 in primary tumors was correlated with patient distant metastasis-free and recurrence-free survival. Modulation of POP1 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
WDR53 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that WD repeat domain 53, encoded by WDR53, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. WDR53 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of WDR53 in primary tumors was not correlated with patient survival outcomes. Modulation of WDR53 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Introduction of management and organization
Authors: nabila Salsa
Published: September 2023

1.1 Who Are Managers?1.2 What Is Management?1.3 What Do Managers Do?1.4 What Is An Organization?1.5 Why Study Management?