bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnostics possibilities of erythrocytes analysis by the method of laser interference microscopy
Authors: Deryugina A. V. , Ivashchenko M. N. , Ignatyev P. S. , Belov A. A. , Petrov V. A.
Published: February 2021

The morphofunctional state of erythrocytes significantly changes by the onset and progression of various diseases, as well as in critical conditions, injuries, accompanied by severe tissue damage. This leads to a violation of microcirculation and has an effect on hemorheology in general. In connection with this, there is a need for the development of adequate methods for assessing the functional activity of erythrocytes. The aim of the work was to study the possibilities of laser interference microscopy in the analysis of the functional state of erythrocytes. The results allowed us to quantify the state of the phase height and phase diameter of erythrocytes. Analysis of the surface nanostructure gave a qualitative assessment of the functional activity of cells. The following patterns were revealed: the action of adrenaline causes the appearance of echinocytes with an increase in phase height and decrease phase diameter and the appearance of spicules on the surface of cells. The action of cortisol leads to a decrease in the phase height and the phase diameter with the appearance of numerous loosening of the structure of the cell surface. Moreover, the traditional method of analyzing the distribution of erythrocytes in a population by morphology (discocytes, stomatocytes, and degeneratively altered cell forms) did not reveal statistically significant differences. Thus, the results indicate that the interference microscopy method allows a qualitative assessment of the morphofunctional activity of native cells. This increases the information content of the analysis and leads to the objectification of data on the functional capabilities of erythrocytes.
Research of spontaneous and stimulated functional activity of platelets in patients with different types of atrial fibrillation
Authors: Ogurkova O. N. , Suslova T. E. , Batalov R. E.
Published: February 2021

Platelet function testing is widely used to diagnose disorders of the cellular link of hemostasis. The study of platelet aggregation activity is relevant for the prevention of thromboembolic complications in atrial fibrillation and monitoring the effectiveness and safety of therapy. In this study, a comparative analysis of spontaneous and stimulated platelet aggregation in groups of patients with two types of atrial fibrillation was performed - paroxysmal and persistent. The effect of β-adrenoblocker therapy on platelet aggregation activity in patients with atrial fibrillation was also studied. Platelet aggregation activity was studied using the method of G. Born in the modification of Z.A. Gabbasov on a two-channel laser analyzer “Biola”. Collagen at a concentration of 2 mg / ml and adrenaline in a concentration range of 2.5-10 μg / ml were used as aggregation-promoting agents. It has been established that spontaneous aggregation potential and collagen-induced platelet aggregation depend on the type of atrial fibrillation, as well as on the presence or absence of β-blockers in therapy. The response of platelets to stimulation with adrenaline depends, first of all, on the type of atrial fibrillation and the concentration of adrenaline in the reaction medium. The most significant changes were noted in the group of patients with a paroxysmal form atrial fibrillation, taking β-blockers in therapy.
PCR-based diagnosis of whooping cough in the Russian Federation
Authors: Pimenova A. S. , Borisova A. B. , Gadua N. T. , Borisova O. Yu. , Afanasiev S. S. , Petrova M. S. , Afanasiev M. S. , Mironov A. Yu. , Aleshkin V. A.
Published: February 2021

The aim was to determine how often the PCR method is used in different laboratories in Russia. In 2018, we conducted a questionnaire survey in diagnostic laboratories of medical organizations and the Centers of Hygiene and Epidemiology that performed PCR studies to identify microorganisms of the genus Bordetella in all 85 Russian regions. We found that in 2013 the PCR was used in 33 (38.8%) regions, but in 2017 the number of regions increased to 64 (75.3%). During 2013-2017 the study has not been applied in 21 regions. The number of PCR tests performed in the laboratories of medical organizations was significantly different. There has been an increase in the number of tests for the diagnosis of pertussis among people with clinical signs of infection and among contact persons in foci of infection. Compared to the Centers of Hygiene and Epidemiology, in medical organizations the rate of introduction of the PCR was higher. Between 2013 and 2017 the proportion of samples containing DNA B.pertussis decreased, but the proportion of samples containing DNA of other representatives of the genus Bordetella increased. Moreover, in the case of isolation DNA Bordetella spp. clinicians diagnose «Whooping cough, other unspecified organism», since there is no information on the species of the pathogen. Thus, in order to improve the diagnosis of pertussis, it is necessary to optimize PCR tests by including target genes that allow to identify of currently relevant DNAs of different representatives of the genus Bordetella.
TOMA DE DECISIÓN MULTICRITERIO PARA LA CREACIÓN DE VALOR EMPRESARIAL
Authors: Solana-González Pedro , Vanti Adolfo Alberto
Published: February 2021

A tomada de decisões multicritério para a criação de valor empresarial tornou-se um tema de interesse significativo que, no entanto, ainda não foi suficientemente estudado. As empresas têm dificuldade em determinar os melhores critérios de decisão para a criação de valor. O Processo Analítico Hierárquico é utilizado como método para estabelecer um modelo de apoio à tomada de decisão empresarial. Os resultados mostram uma maior contribuição para a criação de valor de negócio das decisões baseadas no critério de benefícios e estabelecem uma classificação de prioridades nas decisões de TI para criar valor empresarial.
The Effectiveness of Edamame Seed (Glycine max L. Merril) Ethanolic Extract to Fibroblast Count on Second Degree Burn Wound Healing
Authors: Hasanah Arifah Nur , Sutejo Ika Rahmawati , Suswati Enny
Published: February 2021

Burn wound healing process consists of three phases of inflammation, proliferation and remodelling. The number of fibroblasts has increased during the proliferation phase. Oxidative stress in burn may disrupt proliferation through TGF-β inhibition, result in decreased number of fibroblasts and poor burn wound healing. Genistein in edamame seeds has anti-inflammatory, antibacterial and antioxidant properties. Edamame contains vitamins A, C, and E which is also have antioxidant properties. Edamame has been suggested to protect burn wound healing from oxidative stress. This study aimed to understand the effectiveness of edamame seed (Glycine max L. Merril) ethanolic extract (ED) to fibroblast count in second degree burn wound healing. This is true experimental research with post test only control group design. The study was conducted at University of Jember during November until December 2017. The sample of this research was 24 rat models of second degree burn which was made by attaching hot metal (60 ° C) for 5 seconds on the shaved back of the rats. The sample was divided into 6 groups with topical treatment, among others: positive control group (silver sulfadiazine), negative control group (Na CMC 0.5%), group with ED 20%, ED 40%, ED 60%, and ED 80%. Treatment was given for 15 days and skin sample was taken on the 16th day. Observation of the number of fibroblasts was done by taking pictures of histhologic preparations in Hematoxylin and Eosin staining under 400x magnification of light microscope. The number of fibroblast of each picture was processed using Image-J software. In one way ANOVA test, significance value of 0.011 (p≤0,05) indicated that there was at least a significant difference between 2 groups. LSD’s post hoc analysis showed that there was a significant difference in the group ED 20, 40, and 60% compared with negative control.

 

Keyword: burn wound healing, vegetable soybean, genistein, fibroblast count, silver sulfadiazine
Metodologias ativas na educação superior brasileira em saúde
Authors: Souza Leonardo Santos de , Santos Danielle Aparecida do Nascimento dos , Murgo Camélia Santina
Published: February 2021

Apesar dos diversos benefícios mencionados pela literatura acerca do uso de metodologias ativas na educação superior em saúde para a promoção de uma aprendizagem significativa, tais métodos têm encontrado dificuldades para efetivar-se no Brasil. Uma vez que a superação de uma problemática necessita de um diagnóstico que permita intervenções eficientes, este estudo analisou a produção nacional sobre metodologias ativas no ensino superior em saúde entre 2013 e 2018.  Trata-se de uma revisão integrativa em 5 bases de dados nacionais e internacionais, que resultou de 42 estudos elegíveis.  A maior parte da literatura (73,8%), advém de relatos de experiência e séries de casos, (níveis VI e VII de evidência) publicados em 2016 e 2017, realizados por instituições públicas (78,6%) e sem financiamento (71,4%). Foram desenvolvidas nos cursos de Enfermagem (35,7%) e Medicina (19%), buscando compreender a percepção dos estudantes (28,6%) sobre a inserção de metodologias ativas, especialmente da Aprendizagem Baseada em Problemas (25%). As principais vantagens mencionadas acerca das metodologias ativas foram a promoção de autonomia e pensamento crítico e holístico no estudante. Já os aspectos que ameaçam a efetivação da aprendizagem ativa, versaram sobre os currículos tradicionais, infraestrutura precária e, uma formação docente deficitária.  O baixo investimento em pesquisas pode justificar a dificuldade de efetivação das metodologias ativas, reforçando o uso intensivo de uma pedagogia tradicional curricular que reduz o incômodo que uma educação para a saúde brasileira baseada em evidências pode trazer a todos os indivíduos de uma cultura passiva de aprendizagem.
Evidence-Based Policy Suggestion to Improve the Quality and Economic Benefit of Sumbawan Honey
Authors: A.G Pieter Levina , M.B Utomo Marcellinus
Published: February 2021

Attention to the development of Sumbawan honey is still lacking, despite the economic potential of Sumbawa honey can actually be felt even in remote villages. Currently, regional policies focusing on developing forest honey business and improving its quality have not been initiated. Therefore, this research is aimed at mapping technical, social, and governance issues in an effort to increase the economic benefits of honey; and testing the water content of Sumbawa forest honey and compare it with the standards listed in the Indonesian National Standard (SNI). As an end result, this study recommends the necessary local policies to address the issues raised. Through field exploration and semi-structured interviews with 30 respondents, technical, social and governance issues for Sumbawa honey can be mapped. Through testing 15 samples of forest honey harvested from 3 districts on the island of Sumbawa, there were only 7 samples that had water content less than 22% or met SNI standards. Therefore, the water content of the Sumbawa forest honey needs to be lowered to meet SNI honey standards and to increase market share. We conclude that local governments need to proactively go to the field with their policy tools to improve the quality and quantity of marketable honey. This study recommends a policy package that allows the District Office of Industry and Trade or the District Office of Cooperatives and MSMEs to play an active role in the knot of reducing water content and the knot of buying and selling forest honey.
Diversity Of Soil Macrofauna On Several Land Use On Peatlands
Authors: Handayani Wuri , Winara Aji
Published: February 2021

Peatlands are very vulnerable to land use change. Some of the current peatland cover conditions include agricultural cultivation lands, plantations, shrubs and secondary forest. The presence of soil macrofauna as a soil ecosystem engineer can be a bio-indicator of peatland fertility. This study aims to analyze the diversity of soil macrofauna in several patterns of peat land use in cultivated areas. The research was conducted in December 2017 in Rasau Jaya District, Kubu Raya Regency, West Kalimantan Province. The research method used is monolithic technique with descriptive data analysis using the alpha and beta diversity index approach. The results showed that the diversity and diversity of macrofauna species on peatlands were classified as medium and low, with the highest diversity found in secondary forest patterns (H '= 2.09) and the lowest in oil palm plantations (H' = 0.73), while species richness was found. The highest was found in secondary forest (R '= 4.01) and the lowest was in oil palm plantations (R' = 1.42). The highest population density and abundance were the order Isoptera and Opisthopora, while the lowest is Dermaptera. Several groups of macrofauna which are used as bioindicators of land fertility are found in all land use patterns with the dominan order is Isoptera and Opisthopora. Soil temperature and acidity conditions affect soil macrofauna population density. The presence of diverse vegetation and adequate canopy can affect environmental conditions and the diversity of soil macrofauna. Based on the diversity of soil macrofauna, cultivation with an agroforestry pattern is preferable to peatlands.
Hybrid Artificial Intelligence Methods for Predicting Air Demand in Dam Bottom Outlet
Authors: Narimani Aliakbar , Moghimi Mahdi , Mosavi Amir
Published: February 2021

In large infrastructures such as dams, which have a relatively high economic value, ensuring the proper operation of the associated hydraulic facilities in different operating conditions is of utmost importance. To ensure the correct and successful operation of the dam's hydraulic equipment and prevent possible damages, including gates and downstream tunnel, to build laboratory models and perform some tests are essential (the advancement of the smart sensors based on artificial intelligence is essential). One of the causes of damage to dam bottom outlets is cavitation in downstream and between the gates, which can impact on dam facilities, and air aeration can be a solution to improve it. In the present study, six dams in different provinces in Iran has been chosen to evaluate the air entrainment in the downstream tunnel experimentally. Three artificial neural networks (ANN) based machine learning (ML) algorithms are used to model and predict the air aeration in the bottom outlet. The proposed models are trained with genetic algorithms (GA), particle swarm optimization (PSO), i.e., ANN-GA, ANN-PSO, and ANFIS-PSO. Two hydrodynamic variables, namely volume rate and opening percentage of the gate, are used as inputs into all bottom outlet models. The results showed that the most optimal model is ANFIS-PSO to predict the dependent value compared with ANN-GA and ANN-PSO. The importance of the volume rate and opening percentage of the dams' gate parameters is more effective for suitable air aeration.
Growth Promotion Function of Bacillus sp. Strains Isolated From Salt-Pan Rhizosphere and Their Biocontrol Potential Against Macrophomina Phaseolina
Authors: Castaldi Stefany , Petrillo Claudia , Donadio Giuliana , Piaz Fabrizio del , Cimmino Alessio , Masi Marco , Evidente Antonio , Isticato Rachele
Published: February 2021

In the last decades, intensive crop management has involved excessive use of pesticides or fertilizers, compromising environmental integrity and public health. Accordingly, there has been worldwide pressure to find an eco-friendly and safe strategy to ensure agricultural productivity. Recently, Plant Growth-Promoting (PGP) rhizobacteria are receiving increasing attention as suitable biocontrol agents against agricultural pests. In the present study, 22 spore-forming bacteria were selected among a salt-pan rhizobacteria collection for their PGP traits and their antagonistic activity against the plant pathogen fungus Macrophomina phaseolina. Based on the higher antifungal activity, strain RHFS10, identified as Bacillus vallismortis, was furtherly examined and cell-free supernatants assays, column purification, and tandem mass spectrometry employed to purify and preliminarily identify the antifungal metabolites. Interestingly, the minimum inhibitory concentration assessed for the fractions active against M. phaseolina, resulted 10 times lower and more stable than the one estimated for the commercial fungicide pentachloronitrobenzene. These results suggest the use of B. vallismortis strain RHFS10 as a potential Plant Growth Promoting Rhizobacteria to efficiently control phytopathogenic fungus M. phaseolina, in alternative to chemical pesticides.
“Domains of Deprivation Framework” for Mapping Slums, Informal Settlements, and Other Deprived Areas in LMICs to Improve Urban Planning and Policy: A Scoping Review
Authors: Abascal Ángela , Rothwell Natalie , Shonowo Adenike , Thomson Dana R. , Elias Peter , Elsey Helen , Yeboah Godwin , Kuffer Monika
Published: February 2021

The majority of urban inhabitants in low- and middle-income country (LMIC) cities live in deprived urban areas. However, statistics and data (e.g., local monitoring of Sustainable Development Goals - SDGs) are hindered by the unavailability of spatial data at metropolitan, city and sub-city scales. Deprivation is a complex and multidimensional concept, which has been captured in existing literature with a strong focus on household-level deprivation while giving limited attention to area-level deprivation. Within this scoping review, we build on existing literature on household- as well as area-level deprivation frameworks to arrive at a combined understanding of how urban deprivation is defined with a focus on LMIC cities. The scoping review was enriched with local stakeholder workshops in LMIC cities to arrive at our framework of Domains of Deprivations, splitting deprivation into three different scales and nine domains. The Domains of Deprivation framework provides a clear guidance for collecting data on various aspects of deprivation, while providing the flexibility to decide at city level which indicators are most relevant to explain individual domains. The framework provides a conceptual and operational base for the Integrated Deprived Area Mapping System (IDEAMAPS) Project for the creation of a data ecosystem, which facilitates the production of routine, accurate maps of deprived “slum” areas at scale across cities in LMICs. The Domains of Deprivation Framework is designed to support diverse health, poverty, and development initiatives globally to characterize and address deprivation in LMIC cities.
STUDI TEMPERAMEN SAPI BALI BERTANDUK DAN TIDAK BERTANDUK (Study on the Temperament of Polled and Horned Bali Cattle)
Authors: Qayyum Abdul , Sudirman Baco , Zulkharnaim Zulkharnaim
Published: February 2021

This study was aimed to determine the nature of the differences in temperament of horned and polled Bali cattle. The research was conducted in February-March 2018 in Maiwa Ranch/Maiwa Breeding Center (MBC) Enrekang regency. The research used 25 heads of Bali Cattle, 19 heads of horned Bali cattle and 6 heads of Bali polled. Temperament test data was analyzed by descriptive and cortisol levels were analyzed using T-test statistical analysis, temperance, and cortisol level test results. Data were analyzed using covariance analysis. The results of this study indicated that according to the temperament tests parameters (pen score, chute score, chute exit velocity), Bali polled were tamer than Bali horned cattle. Cortisol levels of Bali polled also observed lower than the horned Bali cattle
PENGARUH LAMA PENGASAPAN MENGGUNAKAN KAYU KOSAMBI (Schleichera oleosa) TERHADAP SIFAT FISIK DAN AKSEPTABILITAS SE’I DAGING BABI (The Effect of Smoking Duration Using Kosambi Wood (Schleichera oleosa) on the Physical Properties and Acceptability of Se’i Pork)
Authors: Buntu Yan , Sinaga Sauland , Suradi Kusmajadi
Published: February 2021

Se’i is a traditional processed pork product in East Nusa Timor which is made through the smoking process using smoke of Kosambi wood so that the meat is more durable and has a distinctive taste. The objective of the research was to determine the best smoking duration on the physical properties and acceptability of pork. The research was conducted experimentally according to a Completely Randomized Design with three treatments of smoke duration and six replications. The experiments cosisted of 60(P1), 70(P2) and 80(P3) minutes, respectively. Physical properties parameters (water holding capacity, tenderness, and smoking loss) were analysed by analysis of varians, while acceptability parameters (color, taste, and flavor) were determine using Kruskal Wallis test. Polynomial orthogonal test was performed to determine the trends of the effect of treatments on the measured variables. The results of the research showed that duration of smoke curing on pork significantly affect the physical properties especially on the tenderness and smoking loss parameters, but did not influence the water holding capacity of pork. Furthermore, the increasing length of smoking application was followed by the decreasing of water holding capacity value (Y = 41,92-0.250X;  R2 = 0,99), while in contrast, positive trend was observed on the smoking loss variable (Y = 18,98 + 0,226X; R2 = 0,94). On the other hand, tenderness follows the Quadratic pattern as Y = 0.084x2 - 11.97x + 495.0 R² = 1). A majority of panelists in this study also favored of Se’i meat which was smoked by kosambi wood for 60 minutes compared to a longer duration. Therefore, smoking duration for 60 minutes is the best treatment to obtain better physical properties of pork as well as a higher level of acceptance.
PRODUKSI SUSU SAPI PERAH FRIESIAN HOLSTEIN (FH) PADA PERIODE LAKTASI YANG BERBEDA (Milk Production of Friesian Holstein (FH) Cows at Different Lactation Periods)
Authors: Mahmud Ali , Busono Woro , Surjowardojo Puguh , Tribudi Yuli Arif
Published: February 2021

This research was conducted in PT Greenfields Indonesia, Babadan Village, Ngajum Districts, Malang, East Java. The purpose of the study was to compare the milk production of FH (Friesian Holstein) dairy cows in various lactation periods. The material used in this research was data records of Australian FH, which have been developed in the Greenfields Indonesia farm. The data used were from 473 dairy cows, which consisted of 100 heads for each lactation period from the period I up to period IV and 73 heads for lactation period V. The variables measured were milk production 305 day 2X ME, daily milk yield production, peak day production, and the peak lactation. The data were analyzed using analysis of variance, and if the result showed differences, the analysis was continued using the Duncan test. The results showed that the increase in the lactation period significantly (P<0.01) decreased milk production and increased the duration of lactation peaks of FH cows. The highest milk production 305 day 2X ME was in the lactation period II, which was around 10232.90 ± 1036.62 kg/lactation or 32 ± 5.13 kg/day. In this period, the peak day in milk lactation was 71.5 ± 27.5 days, and the peak of milk production was 45.7 ± 4.1 kg/day. In conclusion, milk production increased from the first lactation period to the second lactation period and then decreased in subsequent periods. The peak of the first lactation period was reached longer, then falls in the second lactation period and then increases again at the following lactation period
STUDI EKSPERIMENTAL PERFORMANSI TURBIN SAVONIUS DI PESISIR PANTAI KABUPATEN DEMAK TERHADAP DAYA LISTRIK YANG DIHASILKAN
Authors: Santoso Wahyu , Saputro Herman , Bugis Husin
Published: February 2021

Energy from fossil fuels consisting of petroleum, coal, natural gas containing raw material for energy fulfillment in Indonesia is still very central through the use of raw materials from renewable energy is still very low. In Indonesia the potential for renewable energy such as wind energy needs to be optimized. One of the uses of wind energy is through savonius wind turbine as electricity generators. Characteristics of savonius wind turbine with vertical axis rotors which gave a simple shape, and that able to control low speeds. This is in accordance with regions in Indonesi which have low average speeds.         This experimental study, aims to determine the description of wind potential and determine the performance of savonius wind turbines on the coast of Demak regency on the electrical energy produced. Savonius wind turbine used is made of galvalum material in the form of an S type rotor with diameter 1.1 m and height 1.4 m, using pulley transmission system with multiplication ratio 1:6 dan using generator type PMG 200 W. This research uses the method experiment. Data collection in the form of wind speed, humidity, temperature, rotor rotation speed, voltage and electric curret is carried out at 14.30 to 17.30 Western Indonesian Time. Data Analysis in this study uses quantitative descriptive analysis. The result showed the potential of wind on the coast of Demak regency have an average wind speed of 2,02 m/s with a temperature of 31,34 0C and humidity of 76,96. And the performance of the installed wind turbine produces the highest power 3.5 watt with an electric power coefficient of 0,181 and tip speed ratio around 1,75. From these result, the potensial of wind with performance savonius turbine can generate electricity used for pond lighting in the village Berahan Kulon Kecamatan Wedung.
KINERJA LAPANGAN PENUMPUKAN STASIUN JAKARTA GUDANG PT KERETA API INDONESIA
Authors: Anggadha Pratama Fernaldi , Mulyono Tri
Published: February 2021

By collecting data in primary and secondary forms, namely in the form of direct observation around the stacking field at the Jakarta warehouse station regarding the capacity of the piling field in the form of notes about the situation and conditions in the field, conducting direct interviews with employees of PT Kereta Api Indonesia and the forwarders and recap loading and unloading months June, which was carried out by the author during the Fieldwork Practices (PKL). The data obtained are then analyzed to determine the Yard Occupancy Ratio. The high average use of stacking yards that is not in accordance with the loading and unloading performance and high container deposition can affect the Yard Occupancy Ratio itself. Thus, it is necessary to carry out routine supervision in the stockpiling field and to find out which containers have passed the stockpiling period at the warehouse in Jakarta Station.
KOMPARASI PILIHAN PENGGUNA MODA ANGKUTAN LAUT DI PELABUHAN MUARA ANGKE ANTARA KAPAL DISHUB DAN KAPAL TRADISIONAL
Authors: Nursalim Adi , Mulyono Tri
Published: February 2021

The sea transportation mode is a means or tool used by people to move from one place to another. Sea freight mode in DKI Jakara is expected to provide quality service to the users of the transportation services as well as the service users on board, other than that the passenger characteristics strongly affect passengers in choosing Mode of transportation. Based on the user data of traditional vessels majority of the female users differ from the Dishub ship of the majority of male users. The user's age for both ships is the majority of the age range of 21-30 years, including the majority work of students. The level of user earning both traditional and dishub vessels does not differ the majority have not been income according to the type of work. The purpose and frequency of user journeys of traditional vessels and dishub vessels are no different, with the purpose of the majority being a one-time recreation a year.

The study aims to determine which variables will result in factors affecting the perpetrators and the probability of selecting the mode located in the Muara Angke port between the Dishub ship and the traditional vessel. Data processing uses the Serqual method to determine the number of samples from the population and SPSS program to find out the factors affecting the selection of the modes of traditional vessels of Dishub and vessels.
ANALISIS PRODUKTIVITAS WAKTU BONGKAR STEEL PRODUCT ANTARA SHIP CRANE DAN GANTRY LIFTING CRANE (GLC) PADA MV. VTC PHOENIX (PT. DAISY MUTIARA SAMUDRA)
Authors: Afriyanto Ali , Ladesi Vivian Karim
Published: February 2021

Laporan tugas akhir tersebut bertujuan untuk menganalisis produktivitas waktu bongkar steel product antara ship crane dan gantry lifting crane (GLC) pada mv. vtc phoenix (PT. Daisy Mutiara Samudra) yang lebih efektif diantara kedua alat tersebut. Sekaligus sebagai persyaratan kelulusan dari program studi Diploma III Transportasi Universitas Negeri Jakarta.

Dalam penyusunan tugas laporan akhir ini dengan mengumpulkan data dalam bentuk primer dan sekunder. Data primer berupa wawancara serta observasi obyek ship crane dan gantry lifting crane. Data sekunder berupa data rekap manifest dan standar operasional prosedur. Waktu yang dibutuhkan untuk membongkar coils menggunakan GLC yaitu 8 jam 23 menit dan waktu yang dibutuhkan untuk membongkar coils menggunakan ship crane yaitu 10 jam. Dapat disimpulakan bahwa alat yang paling efektif dalam bongkar coils ialah GLC, karena mempunyai kapasitas angkut yang besar.
Concurso público para cargos da Magistratura e do Ministério Público: a adequada interpretação da norma constitucional de experiência prévia
Authors: Marrara Thiago , Recchia Paulo Victor
Published: February 2021

O instituto jurídico do concurso público tem como função precípua a seleção do pessoal para os cargos e empregos na Administração Pública. Afastando-se da lógica patrimonialista, a promoção da eficiência das funções estatais e a necessidade de máxima competitividade no acesso aos cargos e empregos estão intimamente ligados aos princípios democrático e republicano. Contudo, a jurisprudência dos tribunais superiores ainda confunde os requisitos para a investidura no cargo com os da participação no concurso que, além da dúvida quanto ao momento da comprovação desses requisitos, exclui indevidamente do certame candidatos aptos para o exercício da função pública. Para se esclarecer tal distinção, se fará um retrospecto das normas constitucionais sobre o tema, sob o recorte para o provimento dos cargos da Magistratura e do Ministério Público, das normativas do CNJ e do CNMP, além da discussão dos pontos críticos ao posicionamento do STF e a contextualização histórica da Emenda n. 45, no que tange aos motivos que levaram a reforma do judiciário e as regras para ingresso nessas carreiras.
Physical Characteristics and Pain Patterns of Skilled Violinists
Authors: Ackermann Bronwen , Adams Roger
Published: February 2021

This study evaluated the association between upper body physical measurements of skilled violin players and the presence and location of pain related to playing their instruments. To cover a range of playing styles and teaching backgrounds, volunteers were recruited from universities
and orchestras. A group of 32 instrumentalists participated in this study and had their upper limb lengths and ranges of motion measured by a physiotherapist. Between-limb range comparisons revealed some significantly greater range measurements of the left hand compared with the right, which
are hypothesized to represent an adaptation to years of instrument playing. Participants also completed questionnaires detailing the location and duration of any performance-related pains. Regression results identified physical attributes that may be risk factors in the development of pain
problems in violin players with shorter arms. An implication of these findings is that players with right arms shorter than those of their peers may need to pay attention to the positioning of their head on the instrument and to overall instrument placement.
Impact of the Groningen Exercise Therapy for Symphony Orchestra Musicians Program on Perceived Physical Competence and Playing-Related Musculoskeletal Disorders of Professional Musicians
Authors: Greef Mathieu de , Wijck Ruud van , Reynders Koop , Toussaint Joost , Hesseling Rike
Published: February 2021

The goal of the Groningen Exercise Therapy for Symphony Orchestra Musicians (GETSOM) program is to change the limited repetitive motion and playing habits of musicians and stimulate their motion repertoire to reduce the effects of physical overload. The research was motivated directly
by the high rate of absences due to illness in a regional symphony orchestra resulting from playing-related musculoskeletal disorders (PRMDs). The secondary preventive effects of the GETSOM program on perceived physical competence and PRMDs were studied in a clinical trial in which 45 professional
musicians of a symphony orchestra were included and randomized to an experimental (n = 17) and a control group (n = 28). To decrease PRMDs, the GETSOM program focuses on enhancing the perceived physical competence of musicians. The program pays special attention to relaxation, postural exercises
for the shoulder, neck, and lower back; and exercises to enhance physical workload and deal with mental stress. Participation in the 15-week GETSOM program has shown a statistically significant (p < 0.05) and clinically relevant (d > 0.20) increase in perceived physical competence and
a decrease in PRMDs in the experimental group compared with the control group. According to a multiple regression analysis, 45% of the decrease in PRMDs was explained by an increase in physical competence. There is evidence that the GETSOM program is efficacious in promoting changes in perceived
physical competence and a decrease in PRMDs.
Velopharyngeal Insufficiency in Woodwind and Brass Players
Authors: Schwab B , Schultze-Florey A
Published: February 2021

Velopharyngeal insufficiency (VPI) has received little attention in the medical literature. The aim of the present study was to determine the extent to which VPI constitutes a problem for woodwind and brass musicians. A total of 148 musicians (professionals from a symphony orchestra
and students, the latter mainly from a national youth orchestra) were asked if they were aware of the phenomenon of VPI and whether they experienced it. Intraoral pressure measurements were performed to determine pressure peaks, mean pressure, and maximum attainable pressures. Of the 148 musicians,
81 were aware of the VPI disorder, and 24 of them showed symptoms of it themselves. Six of the affected musicians reported that VPI occurred in association with colds or stress or the playing of extremely high notes. One musician noted that it occurred only on return from vacation leave. Of
the symptom-free musicians, 15% reported that they noticed symptoms of VPI during their musical training but that these gradually dissipated of their own accord. VPI in woodwind and brass instrumentalists is obviously more common than previously recognized. Despite reports in the medical literature
that predominantly young musicians are affected, in our study only 47% of the individuals with symptoms were school pupils or music students (who overall constituted 41% of the study subjects). Oboists and clarinettists were the most frequently affected, perhaps because they develop relatively
high mean pressures. Although VPI frequently occurs when woodwind and brass musicians are undergoing training and then regresses, it may persist, particularly in instrumentalists in whom high mean pressures form. To prevent persistent VPI, it seems advisable for music teachers to perform pressure
measurements during instructional periods.
Postural Sway of Percussionists: A Preliminary Investigation
Authors: Coker Cheryl A , Bugbee Fred , Huber Austin , Cook Mark
Published: February 2021

The purpose of this study was twofold: (1) to examine the differences, if any, in postural sway across percussive exercises varying in complexity, and (2) to examine the influence of a flexibility program on the postural sway of percussionists. Fourteen percussion majors from a university
music department were assigned into two groups. Participants in the flexibility-training group participated in a 5-week flexibility program. The remaining participants served as a control group. All participants performed a pretest and posttest under eight separate conditions (ranging in complexity)
while standing on a force platform. Comparisons of postural sway across percussive exercises revealed several differences that may have implications for skill development and performance. Statistically significant differences were not found between the flexibility and control groups; however,
subjective observations revealed an increase in the flexibility group’s awareness of their own posture, muscle tension, aches and pains. Consequently, further exploration in this area is warranted.
Sonhar, persistir e concretizar
Authors: Alberto Márcia
Published: February 2021

Este memorial tem o objetivo de narrar alguns fatos e desafios ocorridos na infância e juventude que contribuíram para a minha formação educacional e profissional. Narrar a própria história é reviver todo um processo de aprendizado e percorrer um caminho cheio de escolhas e decisões, responsáveis por te colocar exatamente no local onde você se encontra. Para uma melhor estruturação, o trabalho foi dividido em tópicos e organizado de acordo com a ordem cronológica dos acontecimentos. Como se trata de uma narrativa pessoal, o texto está redigido em primeira pessoa.
Measurement and Modeling of Minimum Miscibility Pressure: A State-of-the-Art Review
Authors: Dindoruk Birol , Johns Russell , Orr Franklin M.
Published: February 2021

This paper gives a critical review of miscibility-measurement techniques published in the open literature along with recommendations and lessons learned. Many of these published methods violate the inherent assumptions for multicontact miscibility (MCM). The confusion often arises from a failure to distinguish between first-contact miscibility (FCM), in which two fluids can be mixed in all proportions without forming two phases, and MCM, in which fluid compositions that arise during the flow of two phases in a porous medium approach a specific critical point within the constraints of the MCM definition.

There are many analytical, numerical, correlational, and experimental methods available to estimate the minimum miscibility pressure (MMP) for MCM flow. The numerous available methods, some of which are quite inexpensive, have caused significant misunderstandings in the literature and in practice regarding their ability to estimate MMP. Our experience has shown that the best methods are those that honor the multicontact process (MCM), in which flow interacts with phase behavior in a prescribed way. Good methods that achieve this are slimtube experiments, detailed slimtube simulations, multiple-mixing-cell calculation methods, and the method of characteristics (MOC). Techniques such as the rising-bubble-apparatus (RBA) and vanishing-interfacial-tension (IFT) (VIT) experiments are subject to significant uncertainties, although they can still provide useful information. Numerous MMP correlations have been developed. They should be used with caution for systems similar to those used to develop the correlation. Use for other fluid systems can lead to significant errors. We discuss the advantages and disadvantages of most current methods and show that various combinations of methods can reduce uncertainty.
The Complex Relationship between Estrogen and Migraines: A Scoping Review
Authors: Reddy Nihaal , Desai Miraj , Schoenbrunner Anna , Schneeberger Steven , Janis Jeffrey
Published: February 2021

Background: Migraines are a chronic disease for millions worldwide and have been hypothesized to be hormonally mediated due to their higher prevalence in females and menstrual associations. Estrogen has been commonly implicated in migraine pathogenesis yet its exact role in the pathophysiology of migraines has yet to be fully understood.Method: We conducted a scoping review of the literature regarding estrogen’s role in migraine pathogenesis and included 19 studies out of an initial 202 in the final review. Two independent reviewers screened and extracted data from included studies based on predetermined inclusions and exclusion criteria.Results: The estrogen withdrawal hypothesis, discussed by 12 of the reviewed studies, is the most discussed theory about estrogen’s role in migraine physiology and describes the association of migraine onset with natural declines in estrogen levels, particularly when estrogen levels fall below 45-50 pg/mL after an extended period of priming. Additional findings suggest that women with a history of migraine have an increased sensitivity to physiologic fluctuations in estradiol levels. Several studies suggest that migraines are associated with menstruation.Conclusion: It appears that estrogen is very likely to play a key role in migraine pathogenesis, but seems to affect patients in different ways depending on their past medical history, age, and use of hormonal therapy. Further research is warranted to isolate the effects of estrogen in each unique patient population, and we believe that studies comparing menstruating women to postmenopausal women could help shed light in this area.Systematic Review registrations: none
Comprehensive analysis of coding and non-coding RNA transcriptomes related to hypoxic adaptation in Tibetan chickens
Authors: Zhang Ying , Su Woyu , Zhang Bo , Ling Yao , Kim Woo Kyun , Zhang Hao
Published: February 2021

Background: Tibetan chickens, a unique native breed in the Qinghai-Tibet Plateau of China, possess a suite of adaptive features that enable them to tolerate the high-altitude hypoxic environment. Increasing evidence suggests that long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) play roles in the hypoxic adaptation of high-altitude animals, although their exact involvement remains unclear.Results: This study aimed to elucidate the global landscape of mRNAs, lncRNAs, and miRNAs using transcriptome sequencing to construct a regulatory network of competing endogenous RNAs (ceRNAs) and thus provide insights into the hypoxic adaptation of Tibetan chicken embryos. In total, 354 differentially expressed genes (DE genes), 389 differentially expressed lncRNAs (DE lncRNAs), and 73 differentially expressed miRNAs (DE miRNAs) were identified between Tibetan chickens (TC) and control Chahua chickens (CH). GO and KEGG enrichment analysis revealed that several important DE miRNAs and their target DE lncRNAs and DE genes are involved in angiogenesis (including blood vessel development and blood circulation) and energy metabolism (including glucose, carbohydrate, and lipid metabolism). The ceRNA network was then constructed with the predicted DE gene-DE miRNA-DE lncRNA interactions, which further revealed the regulatory roles of these differentially expressed RNAs during hypoxic adaptation of Tibetan chickens.Conclusions: Analysis of transcriptomic data revealed several key candidate ceRNAs that may play high-priority roles in the hypoxic adaptation of Tibetan chickens by regulating angiogenesis and energy metabolism. These results provide insights into the molecular mechanisms of hypoxic adaptation regulatory networks from the perspective of coding and non-coding RNAs.
Pyrroloquinoline quinone regulates the redox status in vitro and vivo of weaned pigs via the Nrf2/HO-1 pathway
Authors: Huang Caiyun , Fan Zijuan , Han Dandan , Johnston Lee J , Ma Xi , Wang Fenglai
Published: February 2021

Background: Oxidative stress is a main cause of piglet gut damage and diarrhea. Pyrroloquinoline quinone (PQQ), is a novel redox cofactor with antioxidant properties. However, the effect and mechanism that PQQ supplementation decreases oxidative injury in weaned pigs is not understood. Therefore, the aim of this study is to confirm the effect of PQQ on regulating redox status in weaned pigs and the mechanism for antioxidant function by porcine intestinal epithelial cell line (IPEC-J2) challenged with H2O2.Results: Experiment 1, 144 Duroc × Landrace × Yorkshire pigs (weaned at 28 d) were allocated to four groups: received a basal diet (control) and diets supplemented with 0.15, 0.30, and 0.45 % PQQ. On d 28, growth performance, diarrhea incidence and redox factors were measured. Experiment 2, IPEC-J2 were treated with or without PQQ in the presence or absence of H2O2 for indicated time points. Experiment 3, IPEC-J2 were transfected with or without Nrf2 siRNA, then treated according to Experiment 2. The cell viability, redox factors, protein of tight junctions and Nrf2 pathway were determined. In vivo, PQQ supplementation demonstrated dose-related improvements in average daily gain, and gain to feed ratio (Linear P < 0.05). During d 0-28, compared to controls, 0.45% PQQ supplementation for pigs decreased diarrhea incidence and MDA content in liver and jejunum, and increased concentration of SOD in liver; 0.3% PQQ supplementation decreased ileal and liver MDA concentration; and 0.15% PQQ supplementation decreased ileal MDA concentration (P < 0.05). In vitro, compared to cells cultured with H2O2, pre-treatment with PQQ increased cell viability, tight junction proteins expression including ZO-1, ZO-2, occludin and claudin-1; and decreased ROS concentration and level of Caspase-3 (P < 0.05); as well as upregulated the ratio of Bcl-2 to Bax and protein expression of nuclear Nrf2, HO-1. Notably, Nrf2 knockdown by transfection with Nrf2 siRNA largely abrogated the positive effects of PQQ pretreatment on H2O2-induced intracellular changes. Conclusions: PQQ administration attenuated oxidative stress in weaned pigs which is associated with activation of Nrf2/HO-1 pathway.
Study on the Influence of Anchorage Length and Pretension on the Working Resistance of Rock Bolt Based on its Tensile Characteristics
Authors: Chang Jucai , He Kai , Pang Dongdong , Li Dong , Li Chuanming , Sun Bingjun
Published: February 2021

In coal mining roadway support design, the working resistance of the rock bolt is the key factor affecting its maximum support load. Effective improvement of the working resistance is of great significance to roadway support. Based on the rock bolt’s tensile characteristics and the mining roadway surrounding rock deformation, a mechanical model for calculating the working resistance of the rock bolt is established and solved. Taking the mining roadway of the 17102 (3) working face at the Panji 3# Well Coal Mine of China as a research site, with a quadrilateral section roadway, the influence of pretension and anchorage length on the working resistance of high-strength and ordinary rock bolts in the middle and corner of the roadway is studied. The results show that when the bolt is in the elastic stage, increasing the pretension and anchorage length can effectively improve the working resistance. When the bolt is in the yield and strain-strengthening stages, increasing the pretension and anchorage length cannot effectively improve the working resistance. The influence of pretension and anchorage length on the ordinary and high-strength bolts is similar. The ordinary bolt’s working resistance is approximately 25 kN less than that of the high-strength bolt. When pretension and anchorage length are considered separately, the best pretensions of the high-strength bolt in the middle of the roadway side and the roadway corner are 41.55 and 104.26 kN, respectively, and the best anchorage lengths are 1.54 and 2.12 m, respectively. The best anchorage length of the ordinary bolt is the same as that of the high-strength bolt, and the best pretension for the ordinary bolt in the middle of the roadway side and at the roadway corner is 33.51 and 85.12 kN, respectively. The research results can provide a theoretical basis for supporting the design of quadrilateral mining roadways.