bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the Anti-Obesity Effects of Specific Medicinal Herbs: Focus on
Herbal Approaches and their Role in Gut Microbiota
Authors: Sharma Sakshi , Mazumder Avijit
Published: July 2024

In the current scenario, obesity is a stimulating health problem and is growing very
rapidly in the world. It is a complex disease caused by the imbalance between the energy intake
and the energy expenditure. There are various diseases associated with obesity, i.e., diabetes, hypertension, cancer, atherosclerosis, and other cardiovascular problems, which produce a serious
impact on the social and financial system of the population. Moreover, changing the lifestyle and
other behavioral changes might help in decreasing weight loss, but it is quite challenging to
achieve. Nearly 10-20% of males and 20-30% of females come under the obese condition. The
most convenient therapy for treating obesity is the use of synthetic drugs available in the markets,
like orlistat and sibutramine, but these drugs have serious side effects, along with this surgical
procedure, and are also not safe. Various herbal medicines and bioactives are preferred as game
changers. Many herbal plants and their bioactive compounds have recently demonstrated promising effects in treating obesity. They achieve this by acting on various signaling pathways, reducing the levels of hormones associated with obesity, and regulating the abundance and composition
of gut microbiota. This review concludes by highlighting the potential role of various herbal
plants in managing obesity.
Cutting-edge Advances in Nanocarrier-Facilitated Topical Drug Delivery Systems for Targeted Skin Cancer Therapy: A Comprehensive Review
Authors: Yadav Bindu Kumari , Patel Riya , Prajapati Bhupendra , Patel Gayatri
Published: July 2024

Skin cancer is one of the most common and complex types of the disease, resulting in
a high mortality rate worldwide. Skin cancer can be treated with chemotherapy, surgery, radiotherapy,
etc. In most cases, a patient's condition and the type of skin cancer determine the recommended
treatment options. As a result of poor penetration of the drug into stratum corneum or
lesions, low efficacy, and higher concentrations of active pharmaceutical ingredients required to
achieve a therapeutic effect, the efficacy of skin cancer therapy has been limited. The high dose
requirement, as well as poor bioavailability at the site of action, causes skin inflammation, which
greatly hinders drug absorption. This review mainly focuses on research on nanocarriers for sitespecific
and controlled delivery of therapeutics for skin cancer treatment. The information related
to various nanocarriers systems for skin cancer will be illustrated. This also focused on patents,
clinical trials, and research carried out in the field of liposomes, niosomes, ethosomes,
nanoparticles, microemulsion, nanoemulsions, gels, nanogels, hydrogels, dendrimers, and nanofibers
for treating skin cancer. Nanotechnology-based therapy has shown great promise in controlling
skin cancer and can be used to deliver drugs more effectively.
An Efficient LC-MS/MS Method for Determining N-nitroso Tofacitinib
Toxicity In the Tablet Form
Authors: P Chitra , KB Premakumari , Bhuvanendran Arun
Published: July 2024

Background and Objective:

Pharmaceutical companies must adhere to rules established
by regulatory agencies in order to monitor pharmaceutical products for nitrosamine contamination.
One type of nitrosamine that can arise during the manufacture of the drug’s formulation and substance
is N-Nitroso Tofacitinib. One pollutant that causes cancer is nitrosamines. Controlling the
amount of nitrosamines in pharmaceuticals and medical supplies is essential. In this study, we devised
a straightforward, sophisticated LC-MS/MS approach to analyse N-Nitroso Tofacitinib present
in Tofacitinib tablets.

Materials and Methods:

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) experiments
were optimised on Jade C18 (5μ, 150 x 4.6 mm), solvent mixture was operated in gradient
program using 10mM ammonium acetate pH 3.2 and acetonitrile with 1.0 mL flow rate. Mass transition
(m/z) 275.3/149.1, 275.3 /147.0, and 275.3/82.1 are used

Results:

The range of linearity is 0.7 - 20.0 ng/mL, with r2 of 0.9952. The Lowest Detection (LOD)
and quantification (LOQ) were 0.7 ng/mL and 1.0 ng/mL respectively. The recovery repeatability
was found to be within the specified range.

Conclusion::

The new approach proved effective for quantifying N-Nitroso Tofacitinib impurity in
Tofacitinib Tablet samples, indicating that it could be applied for regular analysis.
Kounis Syndrome: Review of Clinical Cases
Authors: Yakushin Sergey , Gurbanova Arzu , Pereverzeva Kristina
Published: July 2024

Background:

Kounis syndrome is defined as a combination of acute coronary syndrome
and allergic reactions.

Objective:

In this review, we aim to describe the etiological, clinical, and diagnostic characteristics
of Kounis syndrome.

Methods:

A literature search using PubMed was conducted for the past 32 years using keywords,
resulting in the selection of 761 scientific papers. From these, 217 articles describing 235 clinical
cases were selected. Patients under 18 years of age or without a confirmed diagnosis were excluded.

Results:

Among the 235 patients, type I Kounis syndrome was observed in 49.7%, type II in
27.2%, type III in 5.9%, and a combination of types I and II in 1.0%; in 16.2%, it was not possible
to classify the type of Kounis syndrome. The median age was 57 years, and 68.5% of the patients
were male. The most common causes were antibiotics (32.3%) and non-steroidal anti-inflammatory
drugs (24.3%). The clinical features included chest pain (59.1%), hypotension (74.2%), itching
(30.6%), and dyspnea (30.6%). Electrocardiographic monitoring revealed ST-segment elevation
in 42.9% and was normal in only 5.5% of patients. Coronary angiography was performed in
80.4% of the patients, revealing unchanged coronary arteries in 50.3% of cases.

Сonclusion:

Allergic myocardial infarction is a serious complication of drug therapy.
From Adenoma to Carcinoma: the Unexpected Evolution of an Apparently
Stable Adrenal Lesion
Authors: Cristofolini Giacomo , Maida Giulia , Jaafar Simona , Pigni Stella , M. Grossrubatscher Erika , Zampetti Benedetta , Mazziotti Gherardo , Lania Andrea , Dalino Ciaramella Paolo , Chiodini Iacopo
Published: July 2024

Background:

There is a lack of solid long-term evidence with respect to the management
over time of adrenal incidentalomas that miss clearly benign radiological features. We
present the case of a 75-year-old man with a non-secreting adrenal mass, apparently stable in
size (14 mm) and unchanged in features for 2 years, but subsequently diagnosed as adrenal carcinoma.

Case Report::

The patient was referred to Grande Ospedale Metropolitano Niguarda in August
2022 due to the presence of a large lesion in the left adrenal site. In 2017, a 14 mm, 20 HU,
round, regular-edged lesion was detected at a CT scan without contrast medium. Over the next
two years, the patient was re-evaluated every 6 months with follow-up CT scans with no apparent
densitometric or dimensional changes in the known lesion. In September 2022, 3 years after
the last CT scan, the patient was hospitalised for pneumonia. An abdominal CT scan acquired
during the hospitalisation showed an increase of the lesion to 14.5x10x12 cm. The patient subsequently
underwent open nephrosurrenectomy, and histological examination confirmed the
presence of an adrenal carcinoma (proliferation index 5%, Weiss score 7). No adjuvant therapy
was administered, and the last CT scan in December 2022 was negative for the recurrence of the
disease.

Conclusion::

Adrenal carcinoma usually presents as a clearly malignant lesion with rapid
growth and a marked tendency to metastasise. This case highlights how an adrenal adenoma
with indeterminate features is worthy of follow-up over time despite its apparent dimensional
and radiological stability [1].
The Relationship between Electroencephalography Recording Results and Magnetic Resonance Imaging Abnormalities and Drug Resistance Focal Epilepsy: A Comparative Analysis Study in Bandung, Indonesia
Authors: Prasetya Taufan , Gamayani Uni , Risan Nelly Amalia
Published: July 2024

Introduction

Drug-resistant Epilepsy (ERO) is a complex problem, both in diagnosis and management, and carries a high risk of death and risk of cognitive and behavioral problems. This study aims to determine the relationship between EEG recording results and structural abnormalities from MRI examination results in Drug-Resistant Epilepsy (DRE).

Methods

Quantitative comparative analysis was conducted to study focal epilepsy recorded in the pediatric neurology outpatient of Dr. Hasan Sadikin Hospital, Bandung, 2018-2023. Data collected from medical records included patient demographics and clinical data, EEG recording results, and MRI examination results. Data were subjected to Chi-square analysis with the alternative Fisher's exact test in SPSS 26. A p-value <0.05 was declared significant.

Results

From 67 samples, 34 DRE subjects and 33 drug-sensitive focal epilepsy (DSFO) subjects were obtained. More significant comorbidities were found in DRFO with a p-value of 0.027 and OR 8.88 (1.03-76.84). There was a significant difference in the results of EEG recordings in the two groups with p <0.001. The different EEG features were significant including slowing, polyspike, and frequency>1/60s. The MRI images were not found to be significantly different. The most common structural lesion found was focal cortical dysplasia in both groups. There was no correlation between MRI and EEG in DRE.

Conclusion

EEG recordings' results were better than MRI images' for predicting DRFO, including images of slowing, polyspike, and frequency >1/60. Both EEG and MRI had their respective values for predicting DRE.
Impact of Weather on Incidence and Mortality of COVID-19: An Application of the ARIMAX Model
Authors: Soodejani Moslem Taheri , Kazemi Maryam , Tabatabaei Seyyed Mohammad , Mahmudimanesh Marzieh
Published: July 2024

Introduction

SARS-CoV-2 is primarily transmitted by direct contact between infected individuals, but other factors, such as meteorology, can affect mortality rates and the incidence of this disease. The purpose of this study was to examine the impact of meteorological factors on COVID-19 incidence and mortality in a center of Iran. In fact, this study sought to pursue two main goals: first, to find climate and air pollutant risk factors that seem to be related to people's respiratory conditions, and their effect on the number of daily cases and deaths caused by COVID-19, and the second one was to use the time series regression model as the appropriate model for such data instead of one-variable models.

Material and Methods

Data collected over time can be modeled and forecasted using time series methods. It is common for time series models to be based on a single response variable, such as the Autoregressive Integrated Moving Average (ARIMA) model. In addition to the number of deaths and confirmed cases of COVID-19 as the response variable, we have also considered meteorological indices as independent variables. ARIMAX time series method was applied in this case.

Results

The ARIMAX model was fitted in five lags (lag time in days). It was found that the average daily temperature in lag 10 and relative humidity in lag 7 were related to the mortality caused by COVID-19. The average visibility also had a significant and inverse relationship with the number of deaths in lag 14 and 7; this relationship was also observed with the number of confirmed cases, so in lag 3, as average visibility decreased, the number of cases increased.

Conclusion

It seems that some factors, such as temperature and severe storms, can affect the severity of the disease and should be considered in such conditions, especially for heart and respiratory patients. Thus, the necessary measures should be taken to reduce the severity of the infection with COVID-19 and the deaths caused by it.
Using an Intuitionistic Fuzzy Map to Evaluate the Effect of Risk Variables
in Supply Chain Management
Authors: Öztürk Hasibe Berfu , Ekici Şule Önsel
Published: July 2024

Background:

The escalating complexity within supply chains can be ascribed to a
constellation of factors, notably globalization, competitive dynamics, burgeoning interconnectivity among supply chain partners, and the continuous evolution of technology. This phenomenon correlates with a heightened prevalence of uncertainties and the advent of novel risks, collectively exerting adverse effects on a diverse spectrum of enterprises. For this reason, recognizing, evaluating, and controlling these risks is crucial in the formation of a profitable, competitive, and long-term, sustainably managed supply chain. To control these risks, supply chain
risk management has become an important field of study and application.

Objective:

This study's main goal is to create a model that aids in the analysis and prediction of
supply chain hazards.

objective:

The primary objective of this study is to develop a model that helps to analyze and predict supply chain risks.

Methods:

To achieve this aim, the study starts with a comprehensive examination of the literature to discover relevant papers concerning the topic of interest. Variables were identified using
the identified articles and the document coding standards. Using a fuzzy set technique, the
found variables were then converted into linguistic variables and triangle membership functions.

Results:

Using the adjacency matrix that was acquired during the normalization procedure, an
intuitionistic fuzzy cognitive map was produced. Additionally, scenario analysis was done to
determine what steps to take.

Conclusion:

The final model offers a thorough framework for assessing, forecasting, and determining countermeasures for supply chain risks. This work advances the state of SCRM research and practice.
Identification of Epitope Against Omicron Variant of SARS-CoV-2:
In Silico Vaccine Design Approach
Authors: Kaur Manpreet , Ram Gobind
Published: July 2024

Background::

SARS-CoV-2, which causes COVID-19, resulted in a global pandemic, and
there were millions of confirmed cases and deaths worldwide. The vaccines were developed and
distributed to help control the spread of the virus. The numbers and information related to the
COVID-19 pandemic have likely evolved. Therefore, rapid immunological epitope identification
would be a useful screening technique for vaccine candidates.

Objective::

The aim of this study is to anticipate the protective epitopes for vaccine development
using bioinformatics methods and resources

Methodology::

The SARS-CoV-2 genome and protein sequences were retrieved. Furthermore, using
the ABCpred server, sequential B-cell epitope analysis was carried out. The Ellipro algorithm was
used to forecast discontinuous B-cell epitopes. Moreover, by utilising the NetCTL server, a sequential
T-cell epitope analysis was carried out. Furthermore, the 3D structure of the peptide was created
using the PEP-FOLD3 server, and the 3D structure of the HLA molecule was identified using the
homology modelling tool. The molecular docking was performed by AutoDock Vina.

Results::

There were 20 B-cell epitopes altogether, of which 11 are highly antigenic. After assessing
the antigenicity and toxicity of each resultant epitope, it was determined that the epitope
SVLYNLAPFFTFKCYG is highly antigenic. Then, out of the 6 T-cell epitopes we had found,
"RSYSFRPTY" was chosen as the epitope most suited for further research. Consequently, 72.42% of
the population is covered overall. The structure that was generated was refined and energyminimized.
RSYSFRPTY's binding affinity to the groove of HLA-B*15:01 was determined by docking
study to be -7.5 kcal/mol. PyMOL's visualisation of the docking result for predicting binding
sites.

Conclusion::

The final B-cell and T-cell epitopes are “SVLYNLAPFFTFKCYG” and
“RSYSFRPTY” in terms of antigenicity score and nonallergenic and nontoxic qualities. An in Silico
study indicated that our hypothesised T cell epitope “RSYSFRPTY” had a greater affinity for binding
with its receptor, which might elicit an immune response against the omicron variant.
Constanter igitur et fideliter: Il paradigma teologico damianeo nel prologo del De divina omnipotentia
Authors: Limonta Roberto
Published: July 2024

The studies on Peter Damian’s De divina omnipotentia generally approached it from the first chapter, where the issue of the divine capacity to restore the lost virginity of a maiden is introduced. The brief prologue, instead, has received little attention. Aim of this paper is: 1) to focus on this prologue, showing how it contains in nuce (together with his epilogue in the XVI chapter) the foundations of the theological paradigm by which Peter Damian discusses the temporal dilemma and his relation-ship with the divine omnipotence; 2) to explain how this paradigm is to be understood as the horizon of meaning that supports and explains the Peter Damian’s conception of the eternity as a divine co-gnitive mode, so resolving, from an epistemic point of view, the problems about the necessity of the past relating to God’s omnipotence.
cum cognitio sit assimilatio. Conoscenza, assimilazione e intelletto nel De venatione sapientiae di Cusano
Authors: Carannante Salvatore
Published: July 2024

Written between 1462 and 1463, Cusanus’ De venatione sapientiae can be considered as one of the most cogent expressions of his mature thought. This paper aims at exploring the background and the theoretical role played, in this work, by the concept of cognitio; it will be also outlined the strong con-nection between cognitio and other crucial ideas and images of Cusanus’ philosophy e.g. intellectus, imago, speculum and especially assimilatio.
Alfonso Briceño O.F.M. (1587–1668) e a sua Controvérsia sobre a visão de Deus: notas sobre a renovação do debate acerca da cognição intuitiva e da cognição abstrativa no scotismo do século XVII
Authors: Pich Roberto Hofmeister
Published: July 2024

Alfonso Briceño OFM (1587–1668), born in Santiago de Chile, was one of the great masters of Latin American colonial scholasticism. Among his twelve Controversiae (published in Madrid, in 1639-1642, in two volumes), the Controversia 9 stands out for its extension and for its focus on epistemo-logical subjects – for the rest, Briceño mostly discusses, in his work, the metaphysical groundings of the doctrine of God and of the Trinity. We have in Controversia 9 a kind of Tractatus de visione Dei. Its purpose is to explain the cognitive possibility and the nature of the cognition of God, and this is understood, in fact, as “visio Dei.” Precisely here Briceño resumes and proposes his own version of the central debate in Scotism about the difference between notitia intuitiva and notitia abstractiva. In this brief study, we aim at characterizing the “treatise” on the vision of God, the aspects of the dis-tinction between intuitive cognition and abstractive cognition and, in special, the way how Briceño discourses on one core issue: the perfection and the immediacy of intuitive cognition, which can only be understood from the debate on the species that seem to compose human cognitive acts.
Nihil sub sole novum? A crítica jesuíta às explicações tomistas acerca da doutrina da iluminação
Authors: Silva Paula Oliveira e
Published: July 2024

Based on the explanation given by three sixteenth-century Portuguese Jesuits to the question on how the agent intellect illuminates the phantasm we analyze the criticism that the three make to a set of opinions presented by the via Thomistica to the problem at issue. In this study, the answer to the question about the production of the intelligible by the agent intellect is framed in the context of the controversy which took place at the end of the fifteenth century about the possibility of rationally demonstrating the immortality of the soul. The study shows that, in criticizing the position of the Thomists, the Jesuits aim to elaborate an answer that not only clearly shows the superiority, auto-nomy and immateriality of the agent intellect in the production of the intelligible but also serves as a solid foundation for demonstrating the immortality of the soul.
Unveiling the Influences of Personality Traits, Self-efficacy, Parental Background, and Economic Situation on Entrepreneurial Despondency among Generation Z
Authors: Suryawirawan Okto Aditya ,   Sekolah Tinggi Ilmu Ekonomi Indonesia Surabaya, Indonesia, Suhermin Suhermin , Suwitho Suwitho , Bon Abdul Talib ,   Sekolah Tinggi Ilmu Ekonomi Indonesia Surabaya, Indonesia,   Sekolah Tinggi Ilmu Ekonomi Indonesia Surabaya, Indonesia,   Universiti Tun Hussein Onn Malaysia, Malaysia
Published: July 2024

The economic challenges faced by Indonesia for the past couple of years, including substantial losses and a rise in bankruptcies, coupled with the ongoing impact of global tensions between Russia and Ukraine, underscore the crucial role of entrepreneurs in mitigating unemployment and fostering economic recovery. This study uses non-probability purposive sampling towards 205 students. This study uses partial least square through SmartPLS to analyze the results. The research examined the relationship between personality traits, self-efficacy, parental background, economic situation and entrepreneurial despondency among Generation Z. Among personality traits dimensions, risk-taking propensity was found to have no impact on entrepreneurial despondency, innovativeness was found to have no impact on entrepreneurial despondency, and optimism was found to have a negative impact on entrepreneurial despondency. Self-efficacy found to have a negative impact on entrepreneurial despondency. The impact of risk-taking propensity, innovativeness and optimism on entrepreneurial despondency were mediated by self-efficacy. Parental background was found to have no impact on entrepreneurial despondency and did not moderate the effect of self-efficacy on entrepreneurial despondency. Economic situation was found to have a negative impact on entrepreneurial despondency but failed to moderate the effect of self-efficacy on entrepreneurial despondency. These findings contribute to the theoretical understanding of the factors influencing Generation Z's entrepreneurial intentions, offering insights for educators and policymakers seeking to enhance Generation Z's entrepreneurial inclination.
The Effect of Transactional Leadership, Transformational Leadership, Creative Self Efficacy on Innovative Work Behavior and Employee Performance Moderated by Digital Literacy
Authors: Effiyaldi Effiyaldi ,   Prodi Manajemen, Fak. Ilmu Manajemen dan Bisnis. Universitas Dinamika Bangsa, Indonesia, Mulyono Herry , Suratno Eddy , Pasaribu Johni Paul Karolus ,   Prodi Manajemen, Fak. Ilmu Manajemen dan Bisnis. Universitas Dinamika Bangsa, Indonesia,   Prodi Manajemen, Fak. Ilmu Manajemen dan Bisnis. Universitas Dinamika Bangsa, Indonesia,   Prodi Kewirausahaan, Fak. Ilmu Manajemen dan Bisnis. Universitas Dinamika Bangsa, Indonesia
Published: July 2024

Innovative Work Behavior and Employee Performance moderated by Digital Literacy has many benefits. To get these benefits, it is necessary to have the roles that supports the creation of Innovative Work Behavior and Employee Performance moderated by Digital Literacy. The purpose of this study is to build an understanding of the roles of Transactional Leadership, Transformational Leadership, Creative Self-efficacy In Innovative Work Behavior and Employee Performance moderated by Digital Literacy. The nature of this study is explanatory research.Data collection through questionnaire.The sampling method was target sampling. The sample size was 250 SME employees in Jambi city, and structural equation modeling (SEM) with his AMOS software was used for data analysis. The results of this study suggest that Transactional Leadership, Transformational Leadership, Creative Self -efficacy has a significant effect on Innovative Work Behavior and on Employee Performance. Digital Literacy strengthens the link between Innovative Work Behavior and Employee Performance. From the data it is recommended to increase the Transactional Leadership, Transformational Leadership, Creative Self-efficacy, and Digital Literacy to Improve the Innovative Work Behavior and Employee Performance.
Analysis of MSME’s Financial and Business Improvement Model through Digital Economy Services and Fintech Strategy
Authors: Subkhan Farid ,   School of Business, IPB University, Bogor, Indonesia, Maarif Mohammad Syamsul , Rochman Nurul Taufiqu , Nugraha Yudhistira ,   School of Business, IPB University, Indonesia,   Faculty of Economics and Business, Perbanas Institute, Indonesia,   School of Business, IPB University, Bogor, Indonesia,   The National Research and Innovation Agency (BRIN), Jakarta, Indonesia,   School of Computing, Telkom University, Bandung, Indonesia
Published: July 2024

The development of digital technology contributes significant roles to businesses, including micro, small, and medium enterprises (MSMEs). It raises the digital economy and fintech services to the MSMEs market, such as peer-to-peer lending, digital payment, crowdfunding, digital assets, e-commerce, social commerce, etc. This research aims to analyze MSMEs financial and business improvement model by using MSME’s digital economy products and fintech penetration strategy in Indonesia. This study employed a mixed research method by integrating the Delphi technique and the Analytical Hierarchy Process (AHP). The Delphi method was used to identify criteria or construct for the research framework, while AHP was used to evaluate and determine the score and priorities of the MSMEs financial performance criteria, business goals, digital economy’s alternative products, and fintech penetration strategies. The Delphi method consists of round 1 – to explore the research framework, round 2 – to rank the research indicators, followed by AHP at round 3. The study involves 20 expert panels of MSMEs in greater Jakarta. This study found that the use of digital economy products – particularly fintech will enhance MSMEs’ financial performance by increasing sales volume and business profits. It helps them achieving business goals by increasing their revenue and expanding their business. MSMEs need digital payment and mobile banking as vital fintech services. This study also provides strategic guidance to fintech players and government to effectively penetrate fintech products to MSMEs mainly through knowledge dissemination and digital knowledge improvement.
Revolutionizing Payment Trends: Balipay E-Wallet Technology Acceptance with Trust Mediation
Authors: Melianthi Ni Kadek Indah ,   Master of Management Postgraduate Program, Universitas Pendidikan Nasional, Indonesia, Darma Gede Sri ,   Master of Management Postgraduate Program, Universitas Pendidikan Nasional, Indonesia
Published: July 2024

The trend towards a cashless society in Indonesia is rapidly advancing, driven by the introduction of Bank BPD Bali's innovative e-wallet, Balipay. However, the bank faces significant challenges amidst escalating competition from other e-wallet products. This research addresses these challenges by examining the factors influencing users' interest in adopting and using Balipay. Utilizing the Technology Acceptance Model (TAM), the study considers perceived usefulness, perceived ease of use, and additional constructs related to perceived security and trust regarding the Balipay e-wallet. Data for the research was collected through an online survey involving 180 active Balipay users in Bali, and the analysis was conducted using Structural Equation Modeling (SEM) through the SmartPLS 4 tool. The findings indicate that perceived usefulness has a significant and positive impact on user interest, whereas perceived ease of use and security perception do not significantly affect user interest. Furthermore, the study reveals that perceived usefulness, ease of use, and security positively and significantly influence user trust. Trust mediates the relationship between perceived usefulness, ease of use, and security concerning user interest in Balipay. In practical terms, the research offers valuable insights for e-wallet service providers like Balipay, enhancing their understanding of user behavior. Service providers are also obliged to prioritize user-related interests, with the aim of increasing interest while building and maintaining a higher level of trust. Therefore, this research was conducted with the aim of providing us with an in-depth understanding of various user behaviors and providing concrete guidance for service providers to face the challenges of a larger and more dynamic market.
Innovation and Firm Competitiveness as Intervening Variables in Improving Financial Performance of MSMEs
Authors: Soesetio Yuli ,   Universitas Negeri Malang, Indonesia, Soetjipto Budi Eko , Handayati Puji , Winarno Agung , Rudiningtyas Dyah Arini , Mawardi Moh. Cholid , Realita Tasnim Nikmatullah ,   Universitas Negeri Malang, Indonesia,   Universitas Negeri Malang, Indonesia,   Universitas Negeri Malang, Indonesia,   Universitas Islam Malang, Indonesia,   Universitas Islam Malang, Indonesia,   STIE Indocakti Malang, Indonesia
Published: July 2024

Micro, small, and medium enterprises (MSMEs), especially those operating in the craft industry, often remain overlooked and receive minimal attention from researchers and policymakers even though they have an important role in increasing exports and employment in Indonesia. Nevertheless, craft MSMEs face significant challenges in maximizing innovation and enhancing competitiveness to improve financial performance. Hence, this study aims to investigate how innovation and firm competitiveness influence the financial performance of craft MSMEs. This study utilizes the SEM AMOS analysis tool with data from 403 business actors across three craft centers in West Java: Tasikmalaya, Majelengka, and Bandung. The findings reveal that product, process, and green innovation significantly influence and partially mediate the connection between entrepreneurial orientation and competitiveness. Competitiveness completely mediates the influence of product and green innovation on craft MSMEs' financial performance. Meanwhile, process innovation significantly impacts financial performance both directly and indirectly, emphasizing its importance in enhancing competitiveness and financial outcomes. Continuous improvement and innovation are crucial for boosting competitiveness and financial performance.
Measuring Fintech’s Health: Cash Management and Risk on Firm Performance
Authors: Champaca Mychelia ,   Faculty of Economics and Business, Brawijaya University, Indonesia
Published: July 2024

The development of financial institutions is in line with the massive development of the internet and technology, so the growth of fintech financial institutions is currently still an interesting topic to discuss. Most research on fintech uses a qualitative approach; this is because the topic of fintech is still in its early stages of development. By using a quantitative approach, this research makes a different contribution, namely by measuring the performance of fintech in Indonesia as a study of the context of developing countries. In addition, most research on fintech is still in the form of definitions and ecosystems of fintech financial institutions. Studies on fintech performance are still limited; this is explained by access to fintech financial report databases that have not been published standardly. This study examines the health of fintech financial institutions by looking at their influence on cash management and corporate riskiness. Studies included testing peer-to-peer lending fintech companies registered with the OJK and making observations during 2019–2022. The analysis method used was ordinary least squares regression from panel data. The results of the study show that there is no influence of cash holdings on company performance. A significant influence is shown by the negative influence of risk using the solvency ratio, although when measured using the liquidity ratio, the results are not significant. The test results prove the role of transactional motives in cash management for fintech companies in Indonesia.
INQUIRY-BASED LEARNING TRAINING AS A PEDAGOGICAL COMPETENCE IMPROVEMENT OF MTS. NURUL HUDA TEACHERS
Authors: Mohamad Anas  , Millatuz Zakiyah  , Triya Indra Rahmawan  , Mokhamad Rohma Rozikin
Published: July 2024

Based on the 2018 PISA report, the literacy and analytical abilities of Indonesian students are still very low. Poor literacy and analytical competence can be one of the factors that cause the low comprehension ability of Indonesian students in understanding and reading information. One method that has been proven to improve students' competence and skills, especially in analytical skills and increase students' curiosity is inquiry-based learning. Unfortunately, not all teachers have the pedagogical competencies needed to conduct inquiry learning. This problem is also seen in teachers in MTs. Nurul Huda Malang. Therefore, this community service activity is carried out to increase the capacity and pedagogical competence of teachers to improve the quality of learning that can trigger analytical attitudes in students. The implementation of service is carried out through several stages, namely: surveys and learning observations, training syllabus design, training implementation, and training evaluation. From the results of the implementation evaluation, it is known that the inquiry learning training is very useful and can be immediately applied by the teacher. In addition, there are other opportunities in the future to carry out training related to digital learning media needed by teachers in MTs. Nurul Huda Malang.
DIGITAL TOURISM GUIDE BOOK AS AN EFFORT TO INCREASE VISITOR SATISFACTION OF SEBATU VILLAGE, TEGALLALANG DISTRICT, GIANYAR CITY
Authors: Edvin Eka Nur Rochim  , Zakiyatul Wachdaniah Taulina
Published: July 2024

Increasing the number of tourist villages to improve the tourism sector in Indonesia needs to be balanced with the development of innovation and creativity in tourist villages. This also becomes additional work for village officials and communities to empower villages and develop tourism promotions in the Tourism Village. Limitations in developing innovation are an obstacle in tourism promotion. Therefore, a practical, easy, efficient and cheap media innovation is needed to promote Sebatu Village. This made researchers create a Digital Tourism Guide book to increase the satisfaction of visitors who visit Sebatu Village. The research method is quantitative research which uses data and numbers which are then analyzed using statistics. The subjects of this research were 40 subjects who were adjusted to criteria based on purposive sampling techniques. Data analysis and processing using SPSS. Based on the research results, it shows that there is a good influence on the level of visitor satisfaction, the majority of visitor satisfaction in the high category is 75%. Factors that influence visitor satisfaction using the Digital Tourism Guide Book are relevance of information, accuracy and reliability of information, ease and accessibility, as well as presentation of layout and visual design. Apart from that, features, such as location points that are integrated with Google Maps and QR Code, are added value.
PERUBAHAN TRADISI MOMBOLASUAKO (KAWIN LARI) PADA PERNIKAHAN SUKU TOLAKI DI DESA SANGGULA
Authors: Sarnawati Sarnawati , Pinasti V. Indah Sri
Published: July 2024

Penelitian ini bertujuan untuk: 1) mengetahui bagaimana perubahan yang terjadi dalam pernikahan suku Tolaki melalui tradisi mombolasuako¸ 2) untuk mengetahui dampak perubahan tradisi mombolasuako bagi suku Tolaki. Penelitian ini menggunakan metode penelitian kualitatif deskriptif.  Teknik pengumpulan data menggunakan wawancara, observasi dan dokumentasi. Pemilihan informan dalam penelitian ini menggunakan purposive sampling dengan kriteria tertentu. Informan penelitian terdiri atas informan kunci (tolea, puutobu, ketua adat, kepala desa) dan informan biasa (pelaku mombolasuako). Validitas data dalam penelitian ini menggunakan metode triangulasi sumber. Proses analisis data dalam penelitian ini menggunakan analisis model interaktif Miles dan Huberman, mulai dari kondensasi data (selecting, focusing, abstracting, sampling dan transformasi), Penyajian data, dan penarikan kesimpulan. Hasi penelitian ini menunjukkan bahwa perubahan yang terjadi dalam tradisi mombolasuako meliputi 1) mombolasuako mulai tergantikan dengan mowawo niwule dan melanggahako. 2) pemaknaan yang berbeda terhadap mombolasuako, 3) aturan adat yang berlaku dalam prosesi mombolasuako dinominalkan. Proses perubahan dalam tradisi mombolasuako awalnya dilihat sebagai tindakan tradisional, namun saat ini dilihat sebagai tindakan rasionalitas nilai. Hal ini disebabkan oleh faktor internal (kesadaran masyarakat terhadap hukum adat, rasionalitas masyarakat dalam bertindak) dan eksternal (ekonomi). Dampak yang diberikan yaitu pertama dampak positif adalah menurunnya jumlah kasus mombolasuako, efisiensi waktu, masyarakat mulai berpikir terbuka terhadap perubahan. Kedua dampak negatif yaitu nilai simbolik tradisi mombolasuako mengalami reduksi, masyarakat mulai cenderung berpikir instan. Ketiga dampak bagi suku lain yang ada di Desa Sanggula yaitu terjadinya pembauran budaya.
DAMPAK KEHIDUPAN SOSIAL EKONOMI MASYARAKAT PETANI TAMBAK DENGAN ADANYA PEMBANGUNAN YIA KABUPATEN KULON PROGO
Authors: Yoga Yudi Noviantoro Dwi , Pinasti V. Indah Sri
Published: July 2024

Penelitian ini bertujuan untuk mengetahui dampak sosial dan ekonomi masyarakat petani tambak yang terjadi karena pembangunan bandara YIA di Kecamatan Temon , Kabupaten Kulon Progo   serta bagaimana cara mengatasi damapak sosial dan ekonomi bagai masyarakat petani tambak yang terkena dampak. Penelitian ini menggunakan metode penelitian kualitatif. Subyek penelitian ini adalah pemilik lahan tambak, pekerja lahan tambak, dan masyarakat sekitar yang terdampak. Penelitian ini menggunakan teknik purposive sampling. Teknik pengumpulan data berupa observasi, wawancara, dan Dokumentasi. Validitas data menggunakan  triangulasi sumber dan triangulasi teknik. Analisis data menggunakan Miles dan Huberman. Hasil penelitian menunjukkan bahwa adanya  dampak sosial ekonomi yang berifat negatif pada masyarakat petani tambak di kulon progo. Dampak sosial berupa: interaksi sosial pada masyarakat petani tambak menjadi berkurang, lahan petani tambak hilang karena mengalami penggusuran lahan tambak sehingga kehilangan mata pencaharian. Dampak Ekonomi berupa: Petani tambak hanya sebagian saja yang mengalami ganti rugi, mematikan peluang usaha yang mereka miliki karena penggusuran lahan tambak, pengahasilannya cenderung berkurang, menghambat pertumbuhan ekonomi masyarakat petani tambak. Cara mengatasi dampak sosial berupa memberikan penyuluhan kepada masyarakat, dan mobilitas masyarakat petani tambak. Cara mengatasi dampak ekonomi mendorong untuk berwirausaha lain, dan meningkatkan tingkat pendapatan.
STRATEGI ADAPTASI SOSIAL EKONOMI MASYARAKAT DESA WISATA JELOK PASCA BENCANA ALAM BANJIR TAHUN 2017
Authors: Advunansyah Muhammad Wildan Rezki , Hidayah Nur , Martiana Aris
Published: July 2024

Penelitian ini mendeskripsikan mengenai kondisi dan strategi adaptasi sosial ekonomi masyarakat pasca bencana (studi kasus masyarakat Desa Wisata Jelok Kecamatan Patuk Kabupaten Gunungkidul pasca bencana alam banjir tahun 2017). Lokasi penelitian berada di Dusun Jelok. Penelitian ini menggunakan metode kualitatif deskriptif. Pengambilan sampel dengan menggunakan teknik purposive sampling dengan jumlah informan sebanyak sembilan orang. Teknik pengumpulan data dilakukan dengan observasi, wawancara dan dokumentasi. Validitas data yang digunakan adalah triangulasi sumber. Data yang diperoleh kemudian dianalisis secara kualitatif menggunakan metode interaktif Miles dan Huberman meliputi pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian menunjukan bahwa menunjukkan masyarakat beradaptasi akibat adanya bencana banjir yang merusak jembatan sebagai satu-satunya akses sehingga mempengaruhi kondisi sosial ekonomi warga Dusun Jelok. Strategi adaptasi yang dilakukan masyarakat adalah melalui adaptasi aktif dengan membuat jalur alternatif sebelum jembatan dievakuasi. Adaptasi pasif masyarakat memahami resiko banjir setiap musim hujan tiba dengan begitu warga yang memiliki lahan pertanian membuat tanggul darurat. Kegiatan wisata sementara ditiadakan sehingga warga mencari sumber penghasilan di luar desa sebagai adaptasi ekonomi. Kemudian adaptasi sosial, masyarakat pasca banjir melakukan pembagian kerja secara gotong royong saat pembuatan jalur alternatif, proses evakuasi jembatan, sosialisasi mitigasi bencana warga Dusun Jelok.
PERAN PIHAK KETIGA PADA KELUARGA DENGAN POLA KARIR GANDA (STUDI KASUS WANITA PABRIKAN DI KABUPATEN PURBALINGGA)
Authors: Aryo Ambaruny , Hidayah Nur
Published: July 2024

Pola karir ganda yang dialami wanita pabrikan di Purbalingga memunculkan problematika dan  perubahan pola manajerial pada kehidupan keluarga. Pihak ketigakemudian muncul untuk membantu menyelesaikan pekerjaan rumah tangga yangterbengkalai. Penelitian ini bertujuan untuk: 1) mengetahui siapa saja yang termasuk pihakketiga pada keluarga dengan pola karir ganda; 2) mengetahui peran pihak ketiga padakeluarga wanita pabrikan. Penelitian ini menggunakan metode kualitatif, dengan informanwanita pabrikan di Kabupaten Purbalingga yang mengalami pola karir ganda. Informan dipilih dengan teknik sampel snowball. Metode pengumpulan data yang digunakan meliputiobservasi, wawancara, dan dokumentasi. Teknik analisis data menggunakan model analisisinteraktif yang meliputi tahap pengumpulan data, reduksi data, penyajian data, dan penarikankesimpulan. Keabsahan data atau validitas data diperiksa dengan menggunakan triangulasidata. Hasil penelitian menunjukan bahwa 1) Pihak-pihak yang dijadikan pihak ketiga olehwanita pabrikan di Purbalingga dapat diklasifikasikan menjadi dua yaitu yang berasal darisanak saudara (orang tua/mertua atau saudara) dan yang bukan berasal dari sanak saudara(tetangga atau teman sejawat); 2) Peran pihak ketiga yang berasal dari sanak saudara meliputipengasuhan anak, membersihkan rumah, memasak, mencuci dan tidak terbatas waktu dalammengerjakannya. Sedangkan peran pihak ketiga yang bukan berasal dari sanak saudara hanyadalam pengasuhan anak dan dengan waktu yang terbatas yaitu selama wanita pabrikanbekerja.   Kata Kunci: Peran Pihak Ketiga,  Pola Karir Ganda, Wanita Pabrikan
Inequality on the rural-urban axis: women in rural areas
Authors: Bokan Nataša ,   University of Zagreb, Faculty of Agriculture, Zagreb, Croatia, Bašić Ema , Bušljeta Tonković Anita ,   Institute of Social Sciences Ivo Pilar, Regional Centre Gospić, Gospić, Croatia,   Institute of Social Sciences Ivo Pilar, Regional Centre Gospić, Gospić, Croatia
Published: July 2024

Women in rural areas face numerous economic and social barriers, primarily due to unequal access to public services, and limited educational and employment opportunities. Moreover, there is insufficient statistical data to adequately monitor gender equality indicators in rural and urban areas, leading to the economic and social invisibility of (rural) women. The aim of this article is to examine the inequalities between women and men in urban and rural areas in terms of basic socio-economic indicators, education, and employment. In order to contribute to the importance of gender-specific data and analysis, a secondary analysis of data from the Croatian Bureau of Statistics’ [CBS] database regarding several indicators important for monitoring gender equality has been conducted. The data shows that there are inequalities between rural and urban areas and between the genders. In urban areas, significantly more women obtain a university degree than in rural areas, the employment rate of women in rural areas is many times lower than in urban areas, and the availability of certain public services, such as pre-school education (kindergarten), is still significantly lower despite positive changes in rural areas.
Kinetic Model for the Hydrolysis of Olive Oil by Lipase in Absence of Emulsifier
Authors: Márquez Mª Carmen
Published: July 2024

Lipase-catalyzed hydrolysis of olive oil has been studied in the absence of emulsifier. A simple mathematical model to predict the hydrolysis rate is derived from a proposed kinetic mechanism of the reaction. The hydrolytic reaction obeys Michaelis-Menten kinetics with a simultaneous second-order enzyme deactivation. The model predictions closely agree with the experimental results.
Practices Used in Health and Social Services for the Management of Mistreatment Situations towards Adults in a Context of Gender and Sexual Diversity: A Scoping Review
Authors: Couture Mélanie , Gauthier-Mongeon Julien , Simamonika Pearce , Bernard Rosalie , St-Martin Kevin , Lacasse Rosalie , Israel Sarita
Published: July 2024

Research indicates that adults in the context of gender and sexual diversity (GSD) experienced more violence and discrimination than the rest of the population. GSD refers to all the diversities of sexual characteristics, sexual orientations and gender identity of a person or a group. To encourage the use of evidence-based interventions in health and social services, it is important to extrapolate from the scientific literature how mistreatment situations are managed in this context. A scoping review was conducted using the approach of the Johanna Briggs Institute and the Preferred Reporting Items for Systematic Reviews and Meta-analysis Protocols Extension for Scoping Reviews guidelines. In total, 8 databases were searched for relevant studies published in English and in French. Screening according to inclusion criteria (titles, abstracts, and full texts) and data extraction were performed independently by two team members. Twelve studies were included in this scoping review and covered only three types of mistreatments: intimate partner violence, discrimination, and sexual assaults. Findings suggest a need for tools to better identify mistreatment situations in the context of GSD and additional studies to highlight effective interventions using adequate methodology. None of the studies reported data specifically about older adults or regarding key care events related to the management of mistreatment situations (reporting, needs assessment or investigation). Implications include addressing gaps in research and better educating care providers in health and social services in matters related to GSD, to ensure that they have a better understanding of the needs and realities of this population.