bluuebunny/crossref_metadata_2025 huggingface dataset:
Equalizing the Playing Field and Improving School Food Literacy Programs Through the Eyes of Teens: A Grounded Theory Analysis Using a Gender and Sport Participation Lens
Authors: Deslippe Alysha L. , Bergeron Coralie , Wu Olivia Y. , Cohen Tamara R.
Published: February 2025

Background: School food literacy programs (e.g., home economics) are an opportunity to improve the dietary habits of teens. However, the literature suggests that girls and athletes have better food literacy, and it is not clear how school programs contribute to this inequality. To address this, we explored how gender and sport influenced teens’ perspectives of their school food literacy experiences and how they can be improved. Methods: Using semi-structured interviews and a Grounded Theory analysis, we generated a theoretical understanding of how to improve school food literacy programs for athletes and non-athletes of diverse genders. Thirty-three teens were recruited to balance sport participation (n = 18 athletes) and gender (n = 15 boys; n = 14 girls; n = 4 non-binary) based on data saturation. Results: Teens expressed four categories to improve school programs that aligned with principles of the Capability, Opportunity, Motivation and Behaviours (COM-B) Model of behaviour change. Programs should Provide a challenge (e.g., more advanced recipes), Make it fun (e.g., explore new cuisines in interactive ways) and Establish importance (e.g., health impacts). Practice is key for teens’ self-confidence and development of food skills (e.g., meal planning) as well. Boys emphasized Make it fun whereas girls and non-binary teens emphasized Establishing importance. Athletes valued Practice is key more than non-athletes. Conclusions: School programs should relay the importance of food literacy in fun and tailored ways to teens (e.g., meal planning among athletes). It may be especially salient for programs to tailor their activities and messaging, where possible, to appeal to diverse teens who play sports and those who do not.
A Novel Natural Penetration Enhancer for Transdermal Drug Delivery: In Vitro/In Vivo Evaluation and Penetration Enhancement Mechanism
Authors: Zhao Nanxi , Hao Jiale , Zhao Yucong , Zhao Bingqian , Lin Jiayu , Song Jian , Wang Manli , Luo Zheng
Published: February 2025

Objectives: This study aimed to identify and develop a novel, safe, and effective transdermal penetration enhancer derived from the leaves of Perilla frutescens (L.) Britt, and to explore the underlying mechanisms of its penetration enhancement effects. Methods: To evaluate the safety profile of the penetration enhancer, both skin irritation tests and histopathological analyses were conducted. The transdermal enhancement capabilities of the penetration enhancer were assessed in vitro using five model drugs. Furthermore, to gain insights into the penetration enhancement mechanism of this novel penetration enhancer, a range of analytical methods were used, including a spectroscopic technique, differential scanning calorimetry, micro-optical techniques, and molecular docking simulations. Results: Perilla essential oil contained 93.70% perilla ketone (PEK), which exhibited a safety profile superior to that of azone. PEK significantly increased the cumulative skin permeation of all the model drugs (p < 0.05). PEK exhibited the most obvious impact on puerarin penetration, with quantitative enhancement ratios of 2.96 ± 0.07 and 3.39 ± 0.21 at concentrations of 3% and 5% (w/v), respectively. A strong correlation between the enhancement effect of PEK and the physicochemical properties of the drugs was observed. Mechanistic studies revealed that PEK facilitates drug distribution from the solution phase to the stratum corneum (SC). Conclusions: PEK, seldom discussed in former studies, was observed to show extensive penetration enhancement effects by inducing conformational changes in SC lipids and disrupting the tightly ordered bilayer arrangement of lipids. These findings highlight the potential of PEK as a promising and safe natural transdermal penetration enhancer.
Rereading the Phenomenology’s Recasting of Perception: The Path to a Differing and Interwoven Temporality, Imaginal, and Poetic Ontology
Authors: Mazis Glen A.
Published: February 2025

The point of this Special Issue of Philosophies and of this essay is to look deeply into Merleau-Ponty’s Phenomenology of Perception, published in 1945, and to “read backwards” from the later works (whether published, transcripts of the later lectures, or the unpublished notes) in order to find the inchoate ideas that were already present in the Phenomenology that was to be developed into the series of ideas of the later ontology of the flesh of the world. The presence of these inchoate ideas is subtle and not as clearly developed as in the later works, but now we can see them more clearly. The dispersed, decentered, and intermittent sense of self, the circulation of sense into the depth of the world, the radical temporality of institution, the latency of sense, the imaginal lining of all perception and its role in Being, the invisibility of the visible and the poetic flesh ontology will be touched upon in this essay as all of them are developments of the initial move in the Phenomenology to make perception the access to the real. This essay will go further than the many recent interpretations that look at some of these developing ideas to articulate that this is a necessary trajectory from Merleau-Ponty’s starting point in the Phenomenology of Perception and that all these phenomena to which these ideas point can only come forward in their interrelated interwovenness. This would mean that all these strands are integral to the chiasmatic nature of the flesh of the world.
Can Implicit Solvation Methods Capture Temperature Effects on the Infrared Features of Astrophysical Ices?
Authors: Oliveira Daniel A. B. , Bonfim Víctor S. A. , Fantuzzi Felipe , Pilling Sergio
Published: February 2025

Astrophysical ices play a crucial role in the chemistry of cold interstellar environments. However, their diverse compositions, temperatures, and grain morphologies pose significant challenges for molecular identification and quantification through infrared observations. We investigate the ability of implicit solvation approaches to capture temperature-dependent infrared spectral features of CO2 molecules embedded in astrophysical ice analogues, comparing their performance to that of explicit ice models and experimental data. Using DFT calculations and vibrational frequency scaling, we model CO2 trapped in both amorphous (cold) and crystalline (warm) H2O ice clusters. The implicit model qualitatively identifies certain trends but fails to reliably capture the magnitude of frequency shifts and band strengths. Explicit models correctly reproduce the gas-to-solid redshifts for both the asymmetric stretch and bending modes; however, neither approach successfully replicates the experimentally observed temperature-dependent trend in the bending mode. While continuum-like methods may be useful as first-order approximations, explicit modelling of the molecular environment is essential for accurately simulating the infrared spectral behaviour of CO2 in astrophysical ices and for interpreting observational data on ice composition and evolution.
Monitoring of Salivary Secretory Immunoglobulin A Quantified Two Methods During High-Altitude Volleyball Training Camp
Authors: Sone Ryota , Yamamoto Kenji , Tamai Shinsuke , Goji Honoka , Ohishi Kenji
Published: February 2025

Background/Objectives: Volleyball training camps are known to reduce salivary secretory immunoglobulin A (s-SIgA); however, when it begins to decrease is unclear. The validity of a simple device for quantifying s-SIgA is lacking; hence, this study aimed to observe detailed s-SIgA changes during a volleyball training camp after moving to a high altitude and to investigate the difference in s-SIgA response between the two quantification methods, namely, the enzyme-linked immunosorbent assay (ELISA) and lateral flow device (LFD). Methods: Twenty-four male university volleyball players participated in the observational study. Measurements were collected at three points of the training camp (days 1, 4, and 7). The s-SIgA was quantified using conventional ELISA and the new LFD method. Results: The s-SIgA concentrations quantified using the two methods decreased significantly by day 4 (p < 0.05) and continued to decrease until day 7 (p < 0.05). A significant positive correlation was found between the s-SIgA concentrations quantified using the LFD and ELISA (p < 0.05, rs = 0.319). Conclusions: These results indicate that a high-altitude volleyball training camp may suppress oral immune function by day 4 and that the evaluation of s-SIgA concentration using the LFD method is beneficial. A faster and easier method for assessing s-SIgA could contribute to athletes’ condition management strategies.
Mechanisms of Cell Death Induced by Cannabidiol Against Tumor Cells: A Review of Preclinical Studies
Authors: Melo Edilene S. A. , Asevedo Estefani A. , Duarte-Almeida Joaquim Maurício , Nurkolis Fahrul , Syahputra Rony Abdi , Park Moon Nyeo , Kim Bonglee , Couto Renê Oliveira do , Ribeiro Rosy Iara Maciel de A.
Published: February 2025

Commonly known as marijuana or hemp, Cannabis sativa L. (Cannabaceae), contains numerous active compounds, particularly cannabinoids, which have been extensively studied for their biological activities. Among these, cannabidiol (CBD) stands out for its therapeutic potential, especially given its non-psychotropic effects. This review evaluates the antitumor properties of CBD, highlighting its various mechanisms of action, including the induction of apoptosis, autophagy, and necrosis. By synthesizing findings from in vitro studies on the cell death mechanisms and signaling pathways activated by CBD in various human tumor cell lines, this literature review emphasizes the therapeutic promise of this natural antineoplastic agent. We conducted a comprehensive search of articles in PubMed, Scopus, Springer, Medline, Lilacs, and Scielo databases from 1984 to February 2022. Of the forty-three articles included, the majority (68.18%) reported that CBD activates apoptosis, while 18.18% observed simultaneous apoptosis and autophagy, 9.09% focused on autophagy alone, and 4.54% indicated necrosis. The antitumor effects of CBD appear to be mediated by transient receptor potential cation channels (TRPVs) in endometrial cancer, glioma, bladder cancer, and myeloma, with TRPV1, TRPV2, and TRPV4 playing key roles in activating apoptosis. This knowledge paves the way for innovative therapeutic strategies that may enhance cancer treatment outcomes while minimizing the toxicity and side effects associated with conventional therapies.
Deciphering the Effect of Postharvest 1-MCP Treatment Coupled with Low-Temperature Storage on the Physiological Activities and Edible Quality of Melon
Authors: Wang Haofei , Yang Zhiyi , Amanullah Sikandar , Wang Huilin , Liu Bin , Liu Shi , Yang Tiantian , Wang Chaonan
Published: February 2025

Fruits are an important source of a healthy diet due to their essential nutrients for daily intake. Melon is known as a significant fruit crop of the Cucurbitaceae family based on its various dietary benefits, but its shelf life needs to be maintained for long-term usage. 1-Methylcyclopropene (1-MCP) is a cyclopropene-derived synthetic plant growth regulator (PGR) that is used for significantly delaying the ripening process and maintaining the shelf life of climacteric fruits during storage. In this study, freshly harvested melon fruits were fumigated with various concentrations (1.0 µL·L−1, 2.0 µL·L−1, and 3.0 µL·L−1) of 1-MCP treatment for 12 h (h) and stored at low temperature (8 ± 1 °C) for 30 days (d). The obtained results showed that 1-MCP fumigation coupled with low-temperature treatment maintains the postharvest shelf life of melon fruit. It was noticed that the increase in color hue (a* (red/green), b* (blue/yellow), L* (lightness)) was slowed down and the external fresh color was effectively maintained. At the same time, the firmness, soluble solids, titratable acids (TAs), and vitamin C (VC) content seemed to be maintained at a high level; weight loss and cell permeability were reduced; respiratory intensity and ethylene emission were inhibited; and the accumulation of superoxide anions and malondialdehyde (MDA) was also reduced. In addition, an upsurge in the activities of superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), and ascorbate peroxidase (APX) was noticed in melon fruits under the combined treatment of 1-MCP and low-temperature storage as compared with the control group (CK, without treatment), indicating that 1-MCP treatment can effectively enhance the antioxidant metabolism of melon fruits during storage. Overall, we can recommend that the 3.0 µL·L−1 concentration of 1-MCP had the best effect on maintaining the internal and external quality of sweet melon fruit during storage.
Chemical Characterization and Antibiotic-Enhancing Activity of the Essential Oils of Propolis of Melipona quadrifasciata quadrifasciata
Authors: Albuquerque Emílio Sousa , Paulo Cicera Laura Roque , de Oliveira Borges João Arthur , Gonçalves Sheila Alves , Alencar Gabriel Gonçalves , Ferreira do Carmo Judith , de Morais Almeida Angelica Isabely , Santos Maura Lins dos , Almeida-Bezerra José Weverton , da Silva Luiz Everson , Oliveira-Tintino Cícera Datiane de Morais , Coutinho Henrique Douglas Melo
Published: February 2025

This study investigated the chemical composition and potential antibacterial activity of the essential oils from the propolis of Melipona quadrifasciata quadrifasciata (MQP) in samples collected from the cities of Paranaguá and Guaratuba, Paraná, Brazil, during summer and winter. The chemical composition of the oils was analyzed by GC-MS, and their minimum inhibitory concentration (MIC) was determined against standard ATCC strains and some clinical isolates (Escherichia coli 06 and Staphylococcus aureus 10). The essential oils’ MICs were determined using microdilution in 96-well plates and showed no significant antibacterial activity (MIC ≥ 1024 μg/mL) when used alone. However, the essential oils enhanced the action of norfloxacin, gentamicin, and ampicillin, especially against S. aureus 10. The chemical analysis identified 68 compounds, with β-bisabolene and β-caryophyllene as the predominant constituents. Subsequently, the antibiotic-enhancing activity against the clinical isolates was evaluated. The composition of the MQP oils varied according to seasonality and location, influenced by the microclimates of the cities. The results highlight the importance of MQP oils in enhancing antibiotic activity, particularly against Gram-positive bacteria, despite the lack of significant standalone antibacterial activity.
Design and Optimization of the Injection Mold for Rubber Stators in Oil Production Single-Screw Pumps
Authors: Chen Haiming , Miao Chongwei , Lin Guangyi , Yang Weimin , Li Huijin
Published: February 2025

This study aimed to optimize the injection mold for oil production single-screw pump rubber stators. MOLDFLOW2023 analysis post-design determined the optimal gate position and gating system, and it also analyzed the impact of key parameters on quality. The optimization led to a significant improvement in product quality. The most influential factors were mold temperature, melt temperature, and injection time. The best settings were a mold temperature of 100 °C, a melt temperature of 70 °C, an injection time of 30 s, a holding time of 10 s, and a holding pressure of 60 MPa. This resulted in a 1.8–2.7% decrease in volume shrinkage and a 1.3–0.9% decrease in sink index, enhancing the quality of rubber stators and advancing injection molding technology.
Cerebrovascular Thrombosis in Pediatric Ulcerative Colitis: A Case Report
Authors: Sansotta Naire , Di Stasio Fabiana , Amoroso Angela , D’Antiga Lorenzo
Published: February 2025

Background and Clinical Significance: Venous thromboembolism (VTE) is a severe extra-intestinal manifestation that can complicate the course of inflammatory bowel disease (IBD). Among pediatric patients, cerebral thrombosis (CT) is the most common form of VTE associated with IBD. Magnetic resonance imaging (MRI) remains the gold standard for diagnosing cerebral venous thrombosis, allowing visualization of flow absence and intraluminal thrombus. Prompt initiation of treatment with low-molecular-weight heparin (LMWH) is crucial to prevent complications. Follow-up imaging is essential to evaluate venous recanalization and guide therapy duration. However, data on cerebral thrombosis in pediatric patient with IBD remain scarce. Case Presentation: We report the case of a 12-year-old boy with a known history of ulcerative colitis who presented to the emergency room (ER) with a two-day history of headache and vomiting. One month prior to the ER visit, he experienced an IBD flare confirmed through clinical, biochemical, and endoscopic evaluation and was subsequently started on oral corticosteroids. Neurological examination was unremarkable; however, given the persistence of severe headache, a brain MRI was performed, leading to a diagnosis of cerebral venous thrombosis. Anticoagulation therapy with LMWH was initiated immediately. Follow-up imaging with contrast-enhanced MR venography four months later revealed partial resolution of the thrombosis. The patient continued long-term anticoagulation therapy for a total duration of 12 months. Conclusions: Cerebral venous thrombosis is a serious complication of IBD, particularly in pediatric patients. Clinicians should consider this diagnosis in any child with IBD presenting with persistent headache, even in the absence of focal neurological signs. Early diagnosis and prompt anticoagulation therapy are key to improving outcomes in these patients.
Economic and Geographical Impact of Development Poles: Industrial and Commercial Transformations of the Forestry Sector in Gabon
Authors: Maganga Junior Maganga , Jia Xiangping , Ndoutoumou Pamphile Nguema
Published: February 2025

This paper explores the effects of the cessation of forest commodity exports and the implementation of an industrialization strategy in Gabon, drawing on traditional theories of regional growth. The creation of the Nkok Special Economic Zone (SEZ) in 2012, accompanied by its strategic location and significant infrastructure investments, illustrates the application of Rosenstein-Rodan’s “Big Push” and Douglass-North’s “export base” theories. These initiatives also led to a polarization process consistent with the work of Perroux and other theorists of unbalanced regional growth. The study assesses the impact of this SEZ on regions external to the SEZ and the macroenvironment during the period 2014–2022. It highlights the industrial and commercial mechanisms that promote agglomeration economies, technological diffusion, the creation of economic connections, and the structuring into “core-periphery” zones, in accordance with the concepts of Hirschman. The results show a strong positive correlation between industrial income, exports (excluding raw materials), and industrial production. However, the ban on the export of wood raw materials led to a negative relationship between industrial income and exports of these products. Furthermore, the local processing of forest products has promoted industrial diversification, generated new products, and gradually increased added value. The process of economic and geographical polarization is described as a transitional phase of imbalances whose long-term implications require in-depth studies, particularly in the context of countries in the South and underdeveloped environments.
RCoD: Reputation-Based Context-Aware Data Fusion for Mobile IoT
Authors: Tasnim Samia , Pissinou Niki , Iyengar S. Sitharama , Boroojeni Kianoosh G. , Ahmed Kishwar
Published: February 2025

The rapid development of mobile sensing technologies (e.g., smart devices embedded with various powerful sensors) has encouraged the proliferation of the Internet of Things (IoT). Although data reliability and accuracy are crucial in many sensor applications (e.g., air-quality monitoring), it is often difficult to ensure these properties. Mobile IoT’s people-centric architecture allows for more inaccurate and corrupted data. In this manuscript, we are addressing the problem of how to predict data more accurately in the presence of malicious participants who inject false data to manipulate the system. Our goal is to recover those missing or imprecise data values from the correlated data streams. To do so, we propose a Reputation-Based Context-Aware Data-Fusion (RCoD) mechanism that is resilient against on–off and data-corruption attacks. Furthermore, the Contextual Hidden Markov Model-based data prediction facilitates more accurate real-time data prediction. We tested the scenarios where most participants were malicious, injecting false data at varied rates. Our method accurately identified the honest participants based on their reported data and context. We empirically evaluate the performance using Beijing’s air-quality dataset. We compared the performance of our RCoD method against four state-of-the-art methods, and the results justify its superiority.
Autonomous Mission Planning for Fixed-Wing Unmanned Aerial Vehicles in Multiscenario Reconnaissance
Authors: Chen Bei , Yan Jiaxin , Zhou Zebo , Lai Rui , Lin Jiejian
Published: February 2025

Before a fixed-wing UAV executes target tracking missions, it is essential to identify targets through reconnaissance mission areas using onboard payloads. This paper presents an autonomous mission planning method designed for such reconnaissance operations, enabling effective target identification prior to tracking. Existing planning methods primarily focus on flight performance, energy consumption, and obstacle avoidance, with less attention to integrating payload. Our proposed method emphasizes the combination of two key functions: flight path planning and payload mission planning. In terms of path planning, we introduce a method based on the Hierarchical Traveling Salesman Problem (HTSP), which utilizes the nearest neighbor algorithm to find the optimal visit sequence and entry points for area targets. When dealing with area targets containing no-fly zones, HTSP quickly calculates a set of waypoints required for coverage path planning (CPP) based on the Generalized Traveling Salesman Problem (GTSP), ensuring thorough and effective reconnaissance coverage. In terms of payload mission planning, our proposed method fully considers payload characteristics such as scan resolution, imaging width, and operating modes to generate predefined mission instruction sets. By meticulously analyzing payload constraints, we further optimized the path planning results, ensuring that each instruction meets the payload performance requirements. Finally, simulations validated the effectiveness and superiority of the proposed autonomous mission planning method in reconnaissance tasks.
Narrativity and Climate Change Education: Design of an Operative Approach
Authors: D’Orto Emma , Tasquier Giulia
Published: February 2025

Narratives are intrinsic to how humans make sense of the world, helping us structure experiences, interpret complex phenomena, and construct meaning. This sensemaking capacity makes narratives particularly relevant for climate change education (CCE), where learners must navigate global challenges, engage with uncertainty and envision sustainable futures. Yet the characterisation of narratives remains conceptually ambiguous, presenting challenges for leveraging their educational potential. This study addresses this research problem by posing the question: How can we develop an operational definition of narratives for CCE that effectively unpacks the complexity of narrative as a way of thinking and enables analysis and comparison of narrative features for educational purposes? Grounded in Bruner’s theory of paradigmatic and narrative modes of thought, this paper introduces a four-layer framework for categorising narratives based on their “narrativity”. By demonstrating its practical application through an example, this study offers a tool for recognising, selecting, and/or designing narrative forms that align with diverse educational purposes, laying the ground for future research and practices in CCE.
A Networked Game Theoretic Model for Evaluating Resilience in Megaprojects: Integrating Stakeholder Interactions and Lifecycle Adaptability
Authors: Zhang Hongsi , Jiang Shukai , Lin Xingwu , Yu Xiang , Zheng Wenjiang
Published: February 2025

Megaprojects are complex systems comprising interdependent subsystems and diverse stakeholders, each contributing to the project’s resilience and long-term outcomes. Traditional methods for assigning stakeholder influence often assume that stakeholders operate independently when evaluating subsystem resilience. However, these approaches overlook the intricate dynamics—such as competition and collaboration—that frequently characterize stakeholder interactions in megaprojects. This study addresses this gap by introducing a novel framework based on game theory and network analysis to assess megaproject resilience. The model incorporates both stakeholder interactions and subsystem interdependencies, using a networked game approach to dynamically allocate stakeholder weights. These weights reflect cooperative and conflicting relationships among stakeholders. The framework optimizes a stakeholder’s utility function by balancing marginal benefits, costs, and interaction effects, ensuring rational and adaptive weight distribution. The resulting solution represents a unique Nash equilibrium, identified as the optimal configuration for stakeholder influence. To validate the framework, the study applies it to the Jakarta–Bandung High-Speed Railway (JBHSR) megaproject, demonstrating its capacity to integrate theoretical rigor with practical application. Through mathematical proofs and simulations, the research explores how model parameters influence two critical solution properties: order consistency and stability. Comparative analysis with established methods, such as the Analytic Hierarchy Process (AHP) and simple averaging, highlights the proposed model’s superior ability to capture stakeholder dynamics and adapt to the evolving nature of megaprojects throughout their lifecycle. The findings emphasize the model’s utility in delivering more nuanced resilience evaluations by accounting for stakeholder roles, relationships, and contributions. Specifically, this framework advances theory by merging network analysis with game theory to capture dynamic stakeholder influences, while offering practitioners a real-time mechanism to manage and optimize stakeholder interactions for improved resilience across the entire megaproject lifecycle. Its adaptability to full lifecycle assessments makes it a robust and scalable tool for managing resilience in large-scale infrastructure projects, offering valuable insights for both practitioners and researchers.
Touristification and the Territories of Gender-Based Violence in Lisbon
Authors: Galavielle Juliette , Paiva Daniel
Published: February 2025

This study contributes towards the burgeoning literature on the negative social consequences of touristification by uncovering the entanglement of gender violence and the territories produced by tourism in Lisbon’s nightlife districts. Drawing upon a perspective of body-territory, this study questions how gender-based violence affects nightlife workers in a touristified urban centre. The research is based on a year-long ethnographic study of women’s workplaces at night, which includes different forms of observation and a set of interviews with women and non-binary workers. The findings of the study describe the territorial dimension of violence for the workers of Lisbon’s tourism-oriented night life, focusing on the asymmetrical repartition of violence, which varies in its nature and intensity according to the neighborhood, the status of the venue, and the workers’ level of experience and authority in the venue. The conclusion of this study underlines the significance of territory for understanding the dynamics of gender-based violence in the nightlife and discusses future avenues of research on the topic.
Cost-Effectiveness of Introducing Nuvaxovid to COVID-19 Vaccination in the United Kingdom: A Dynamic Transmission Model
Authors: Pritchard Clive , Kutikova Lucie , Pitman Richard , Lai Kira Zhi Hua , Beyhaghi Hadi , Gibbons IIana , Erbe Amanda , Živković-Gojović Marija , Cosgrove Catherine , Sculpher Mark , Salisbury David
Published: February 2025

Background/Objectives: Vaccination against SARS-CoV-2 remains a key measure to control COVID-19. Nuvaxovid, a recombinant Matrix-M–adjuvanted protein-based vaccine, showed similar efficacy to mRNA vaccines in clinical trials and real-world studies, with lower rates of reactogenicity. Methods: To support decision making on UK vaccine selection, a population-based compartmental dynamic transmission model with a cost-utility component was developed to evaluate the cost-effectiveness of Nuvaxovid compared with mRNA vaccines from a UK National Health Service perspective. The model was calibrated to official epidemiology statistics for mortality, incidence, and hospitalisation. Scenario and sensitivity analyses were conducted. Results: In the probabilistic base case, a Nuvaxovid-only strategy provided total incremental cost savings of GBP 1,338,323 and 1558 additional quality-adjusted life years (QALYs) compared with an mRNA-only vaccination strategy. Cost savings were driven by reduced cold chain-related operational costs and vaccine wastage, while QALY gains were driven by potential differences in vaccine tolerability. Probabilistic sensitivity analysis indicated an approximately 70% probability of cost-effectiveness with Nuvaxovid-only versus mRNA-only vaccination across most cost-effectiveness thresholds (up to GBP 300,000/QALY gained). Conclusions: Nuvaxovid remained dominant over mRNA vaccines in scenario analyses assessing vaccine efficacy waning, Nuvaxovid market shares, and the vaccinated population.
Two-Step Optimization Method of Freight Train Speed Curve Based on Rolling Optimization Algorithm and MPC
Authors: Sun Xubin , Li Jingjing , Zhang Wei , Sun Guiyang , Zhang Xiyao , Xu Hongze
Published: February 2025

Given the considerable length and weight of freight trains, their operation can be quite challenging. Improper operation may lead to train decoupling and derailment. Driver Advisory Systems (DASs) are used in some countries to assist train drivers by providing the speed curves, which are desired to be easy to track. Multi-mass train model is a good choice to depict the in-train forces in train speed curve generating, but its application is often hindered by the computation time. A single mass train model is considered as another choice to simplify the computation. To exploit the advantages of the multi-mass and single-mass models, this paper proposes a Two-step Optimization Method to generate the optimal speed curves for the freight trains. In the first step, the Rolling Optimization Algorithm (ROA) is proposed to optimize the speed curve on the basis of the single-mass model, taking the train energy consumption and punctuality as the optimization objectives. In order to assist the driver in operating the train smoothly, the speed curve generated by the ROA was tested on DAS, but it could not be followed accurately in the actual operation. To solve this problem, a Model Predictive Control (MPC) algorithm based on a multi-mass model is adopted as the second optimization step, which takes the output speed curve of the ROA as the reference speed curve. The MPC algorithm will generate a new speed curve, taking in-train forces, energy consumption and punctuality as the optimization indices. Simulations are carried out using the data from the Dalailong railway in China to evaluate the proposed method. The simulation results show that the speed curves generated by the Two-step Optimization Method are smoother than that of the ROA, and the throttle sequences are more conducive for the driver to follow in practical operation. The simulation results show that the energy consumption is reduced by 17.1% compared to that of the ROA simulation. The speed curve also can be integrated into the onboard DAS or the Automatic Train Operation (ATO) system, aiming to obtain a smooth and energy-efficient train operation.
Study on Natural Attenuation of Groundwater Organic Pollutants by Integrating Microbial Community Dynamics and Isotope Analysis
Authors: Shi Jian , Zhang Yiyin , Lai Yuyang , Yang Ruilu , Cai Meng , Fan Susu , Gu Xiaomin
Published: February 2025

This study focuses on a typical chemically contaminated site in the southeastern coastal region of China, investigating the natural attenuation mechanisms of benzene and o-toluidine in groundwater through high-throughput sequencing, physicochemical analyses, and stable isotope techniques. The results demonstrate significant heterogeneity in the spatial distribution and degradation processes of pollutants within the contaminated zones (W27, W28, W31). Environmental factors such as HCO3−, SO42−, and ORP predominantly influence the microbial community structure and functional distribution. Stable isotope data reveal that δD and δ13C enrichment effects are most pronounced in the deep layer (W28_40m), indicating active pollutant degradation, while degradation in the deeper layers of W27 and W31 is constrained by anaerobic conditions and reduced microbial activity. The combined analysis of hydrogen and carbon isotopes elucidates the degradation pathways and dynamic processes of pollutants within the contaminated zones, providing quantitative evidence for natural attenuation mechanisms and scientific support for optimizing site remediation strategies.
Equity-Oriented Multi-Objective Optimization Allocation Strategies for Urban Water Resources
Authors: Zhou Shicheng , Wang Dong , Liu Zhen , Ma Yongqiang , Liu Xin
Published: February 2025

Urban water usage spans diverse sectors, requiring effective management strategies to address increasing demand, limited supplies, and sector-specific needs. In this study, a multi-objective urban water resource allocation model is proposed to balance economic, ecological, and social benefits, focusing on social fairness. The model considers water availability, demand diversity, and environmental factors for optimized resource allocation. An improved zebra optimization algorithm-based multi-objective evolutionary algorithm (ZOA-MOEA/D) is developed, integrating zebra optimization with a decomposition-based approach to overcome the traditional methods’ limitations, improving solution diversity and convergence. ZOA-MOEA/D consistently outperforms the NSGA-II, MOPSO, and MOEA/D algorithms in solution distribution, convergence, quality, and diversity across multiple test scenarios. By applying the model to Ningbo, China, key trade-offs between economic growth, social fairness, living standards, and ecological protection are revealed. These findings provide useful insights into urban water resource management, offering a flexible framework for balancing multiple objectives and supporting sustainable development. Despite some limitations, the approach can contribute to the ongoing development of urban water resources.
Biosphere-centric model of cultural and natural heritage as a tool for sustainable development of countries and the Planet: from traditions to innovations of the digital age
Authors:   Section of synthesis of arts of the Creative Union of Artists of Russia, laureate of the European Academy of Sciences award, Garber N. M.
Published: February 2025

The UNESCO Convention Concerning the Protection of the World Cultural and Natural
Heritage of 1972, ratified by the majority of countries of the Planet, is the first global document
of humanity considering the noosphere of the cultural heritage of humanity as a continuation
of the Earth's biosphere. I built the components of the Convention according to
Maslow's motivation levels and in accordance with the tasks of sustainable development of
the Planet, turning it into an instrument of cultural diplomacy that ensures cooperation of
the countries of the Planet in the productive development of the world ocean of cultures
from traditions to innovations of the noosphere of the 21st century. Within the framework
of the Eurasian approach, the article analyzes Spanish and Tibetan models of thinking in
application to the task of sustainable development of cultural brands of the countries of the
digital age. Based on the cultural parallel of Pushkin's “Gypsies” and Merimee's “Carmen”,
an example of a conscious rethinking of the methods of Eurasian cultural geopolitics as an
instrument of cooperation of cultures in the development of thinking for the sustainable
development of the Planet is built. The article is illustrated with the author's internationally
exhibited visual works created using artificial intelligence, demonstrating the innovative
creative potential of cultural diplomacy in the digital age.
The history of academic research of the ethnic culture of the votes in the XVIII–XX centuries (part two)
Authors:   A.I. Herzen Russian State Pedagogical University, Bogdanov I.S. ,   Department of Cultural Studies, Pedagogy and Arts of the Faculty of World Languages and Cultures, F.M. Dostoevsky Russian Christian Humanitarian Academy
Published: February 2025

The purpose of the study is to provide an overview of the history of academic research of
the ethnic culture of the Votian people; the objectives are to provide a systematization of
scientific developments in this area and to determine their place in the general paradigm
of the study of the Votian people. In addition, it is proposed to introduce a new term into
Russian academic discourse, denoting a scientific complex of studies of the Votian ethnicity.
In this paper, this complex will be referred to by the word “Votology”. The object of this
research, therefore, is the history of Votology; the subject comprises of academic works
published in the field of designated scientific knowledge in the XVIII, XIX and XX centuries.
Documentary journalism as a way to form moral values of student journalists
Authors:   Department of Journalism, Moscow University for the Humanities, Stolyarova Natalya Yurievna , Klyuchanskiy Nikita Romanovich ,   Department of Journalism, Moscow University for the Humanities
Published: February 2025

The article analyzes the stages of development of moral themes in domestic documentaries
and the specifi cs of documentary journalism as a way of developing moral values
in young people in general and student journalists in particular. The study of the issue of
the formation of moral values among Russian youth in general and student journalists
in particular is especially relevant at this stage of development of the media, when the
content presented on digital media platforms displaces classic one, and traditional methods
of education and training gradually become less relevant and give way to the main
educational platform of the younger generation — new media, the information content
of which is increasingly trusted by modern young people.
Civilizational values of Russia and India in the media vocabulary of cultural interaction
Authors:   Department of Cultural Studies and Social Communication, Russian Academy of National Economy and Public Administration under the President of the Russian Federation, Alnurov Dmitriy Yurievich
Published: February 2025

In current geopolitical conditions, Russia and India are examples of unique civilizations
with rich history, formed by spiritual values and traditions, and their cultural interaction
has left a deep mark on the history of both peoples and had a signifi cant impact on modern
social and political processes. Personal experience of interaction with representatives
of Russian and Indian cultures allowed the author to sociologically refl ect on the projections
of basic cultural imperatives on the everyday behavior of representatives of both
cultures and form a generalized idea of the intersection points of their civilizational values.
Theatrical audience: the issue of definition and typology
Authors:   Department of Philosophy, Sociology and Cultural Studies in scientifi c major 5.10.1 Theory and History of Culture and Art, Moscow University for the Humanities, Bondarenko Sofiya Andreevna
Published: February 2025

The article analyzes the problems of the phenomenon of separation of audience in the
opera house. The theoretical and methodological basis of the article is the typology of
listeners by T. Adorno, who distinguishes: “professional public”, “amateurs, connoisseurs
of art”, “a beginner viewer”, and “a mass listener”. In connection with the development of
entertainment culture and the increase in its role in modern society, it becomes relevant to consider the issue of differentiation of the audience in the theater from a scientific point of view. The issue of analysis and typology of the theater audience is the object of this article.
Role of cinema in developing the personality of a modern journalist
Authors:   Department of Journalism, Moscow University for the Humanities, Gutorov Vladimir Dmitrievich
Published: February 2025

The article analyzes the problems of educating the personality of a journalist through the
means of cinema in current conditions. This is due to the growing infl uence of cinema
and the media on society, the educational and awareness-raising potential of cinema,
and the decisive role of the media in shaping public discourse, opinions, and values. In
the modern world, cinema has gone beyond mere entertainment and become a powerful
means of education and enlightenment. With its unique ability to combine art,
technology, and storytelling, cinema offers a universal language that transcends cultural and geographical boundaries. It serves as a mirror to society, reflecting its virtues, vices, dreams, and reality.
PENGARUH INFLUENCER MEDIA SOSIAL TERHADAP MINAT PEMBELIAN ULANG PERAN MEDIASI KEPUTUSAN PEMBELIAN
Authors: Satria Bayuaji Saputra  , Muhammad Sholahuddin
Published: February 2025

This study aims to explain how influencer credibility, attractiveness, and similarity affect repurchase intention through the mediating role of buying decisions. This study uses a quantitative approach with a survey method, and obtained a total sample size of 195. The sampling technique used non probability sampling with purposive sampling technique. Data analysis using SmartPLS 4.0 software, specifically using Structural Equation Model (SEM) analysis. The findings of this study indicate that Social Media Influencers have an effect on purchasing decisions, the relationship between Social Media Influencers has a positive and insignificant effect on repurchase interest, but the mediating role of purchasing decisions provides a positive and significant influence relationship between social media influencers on repurchase interest.
Perancangan Sistem Informasi Pengelolaan Formulir Departemen Administrasi pada PT. United Tractors Tbk-Site-Satui
Authors: Aristi Nina Mia , Khuzairin Rusma , Noor Agustian , Prastyaningsih Yunita
Published: February 2025

PT United Tractors Tbk-Site Satui adalah perusahaan yang bergerak dalam bidang service alat berat dan penyediaan sparepart, bagian dari Astra International yang berpusat di Jakarta, saat ini menghadapi tantangan dalam penggunaan Google Forms untuk pengelolaan formulir karyawan. Kurangnya kontrol akses, izin penggunaan data, dan keterbatasan dalam pelacakan perubahan formulir menyebabkan kerumitan koordinasi dan meningkatkan risiko kesalahan data. Untuk mengatasi masalah ini, sebuah sistem informasi baru dikembangkan menggunakan framework Laravel. Framework ini dipilih karena kecepatan, stabilitas, keamanan data, dan fitur-fitur canggih seperti Blade dan konsep MVC yang dimilikinya. Sistem ini bertujuan untuk mengoptimalkan proses pengajuan administrasi, meningkatkan akurasi dan keamanan data formulir, serta meminimalkan risiko kesalahan dalam pengelolaan data.Sistem kemudian diuji menggunakan Blackbox Testing dan User Acceptance Testing. Hasil pengujian menunjukkan sistem dapat berfungsi dengan baik dan sesuai dengan kebutuhan end user
MILITARY MEDICINE IN HYBRID WARS
Authors: Konyshev I.S. , Zakharov V.A. , Gukasov V.M.
Published: February 2025

The dependence of the construction of anti-epidemic protection of the control system of the tactical formation of troops (forces) and the problem of participation of military medicine in the prevention of mass diseases and ensuring security in the hybrid wars. The conclusion about the necessity of introduction of information technologies, given the characteristics of available programs.
THE INFLUENCE OF BREAST DENSITY ON THE EFFECTIVENESS OF DIAGNOSTIC METHODS IN ONCOLOGY
Authors: Kachanov I.V. , Pechatkin M.M. , Kuznetsov I.A. , Kamyshnikova E.A.
Published: February 2025

Breast cancer is the leading cause of cancer in women worldwide, and the effectiveness of breast cancer detection depends on the structural features of the gland, in particular, on its density. High mammographic visualization is associated with an increased risk of breast cancer development and a decrease in the sensitivity and specificity of the main methods of radiation diagnostics. The article presents current data on the effect of breast density on the information content of mammography, ultrasound, MRI, as well as promising visualization technologies such as tomosynthesis, contrast spectral mammography and molecular imaging methods aimed at increasing the effectiveness of breast cancer detection in women with dense breasts. The relationship between mammographic illumination and molecular subtypes of breast cancer, its im- portance for personalization of diagnostic and therapeutic approaches are discussed.
LA INCLUSIÓN EDUCATIVA
Authors: Silva Giraldo Cesar Augusto , Arenas Joya Lizeth Daniela , Rodríguez Uribe Erika Yulieth , Ortiz Rey Angy Daniela , Reyes Serrano Paola Andrea , Patiño Becerra Fanny Bernarda
Published: February 2025

El presente artículo abordó la temática de la inclusión en la educación, teniendo en cuenta los puntos positivos o a favor que esta tiene. Dicho artículo se generó a partir de una investigación descriptiva, con un enfoque cualitativo y a su vez estableció o se basó en unos referentes conceptuales y teóricos, que ayudaron a la observación y análisis de los puntos positivos que tiene hoy en día la inclusión en el ámbito educativo. Procura realizar un acercamiento de algunos componentes o rasgos que subyacen a las metodologías y estrategias de los procesos de enseñanza-aprendizaje. Esto no se integra o propone como un modelo o respuesta válida, sino como elemento preciso para fomentar la construcción de experiencias diversas que puedan ser productivos y compartidos con otros y que a su vez pueda procrear cambios que inicien la inclusión. Los enfoques presentados arrojan luz sobre cómo algunas estrategias pueden ser útiles para generar diferentes tipos de prácticas educativas que son relevantes para el desarrollo de una filosofía inclusiva
Gangs, mafia, organised groups in prisons: the formal and informal strategies of managing the “public enemy"
Authors: Miravalle Michele
Published: February 2025

How does the label of “public enemy” influence the strategies of managing prisons? Using insights coming from on-the-field research conducted in different countries (mainly inside the prison for gangs in Triángulo Norte – El Salvador, Guatemala, Honduras – and into “high security” units for mafia members in Italy), the article focuses on the forced relationship between two complex organisations, the State and its punitive apparatus on one side and the organised groups, the non-state actor, on the other. Organised groups bring inside the walls of prison their habitus, organisation, leadership, hierarchy, symbols, typical of that continuum. The special units for dangerous prisoners are becoming a transnational strategy for experimenting different forms of relationship between State and criminal organisations: recognition, degradation, desertion and the underestimated desistance.