bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical application of genomic profiling in breast cancer and the TAILORx trial
Authors: Sparano Joseph A.
Published: May 2015

Breast cancer is characterized by clinical and molecular heterogeneity. Microarray-based gene expression has identified distinct expression profiles associated differing prognosis and response to therapy. Newer technologies now permit evaluation not only of gene expression, but also single nucleotide polymorphisms, gene copy number, genomic mutations, and epigenomic or microRNA patterns that modulate gene expression. These state-of-the-art molecular approaches offer new insights into the pathogenesis of breast cancers, and offer the promise to improve the prevention, diagnosis, and management of the disease. Although many gene expression assays have been shown to provide prognostic information that is complementary to classical clinicopathologic features, the clinical utility of such assays is uncertain — that is, how do the results alter patient care, and do patients benefit from that change? Most attention has focused on using these assays to reduce overtreatment in patients with estrogen-receptor positive, lymph node negative breast cancer, which accounts for about one-half of all breast cancers, and about 8% of all cancers in the United States. Evidence suggest that some assays do have clinical utility when used appropriately, usually by reducing overtreatment with chemotherapy in patients who may otherwise have an excellent prognosis with local therapy plus endocrine therapy alone — or “treatment sparing”. Other potential examples of clinical utility include “treatment selection” (selecting individuals for chemotherapy when standard clinicopathologic features would have suggested otherwise) and “treatment direction” (selecting individuals for chemotherapy when clinicopathologic features suggested therapeutic equipoise). There are three breast cancer clinical trials which have integrated multiparameter assays into the clinical decision making, including the TAILORx and CHORUS trials (which use the 21 gene assay) and the MINDACT trial (which uses the 70 gene assay). The results of these trials will inform us regarding the clinical utility of these assays, and provide a valuable resource for evaluating other clinical cancer tests in the future.
The quantitatively analysis of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) and its correlation with response rate of EGFR tyrosine kinase inhibitors (TKI)
Authors: Li Jun , Chen Zhao , Sun Daqiang , Xu Meilin , Zhang Xun , Xu Junpu
Published: May 2015

Background and Purpose: Lung cancer is the most frequent malignant tumor in China. Epidermal growth factor receptor (EGFR) had been validated as one of the most important therapeutic targets of non-small cell lung cancer (NSCLC), and tyrosine kinase inhibitors (TKI) have improved the overall outlook and quality of life for most of EGFR mutation positive NSCLC patients; however, the fact that 30% of EGFR mutation positive patients still do not response to TKIs. The current diagnostic test qualitatively measures the overall EGFR mutation status of the cancer tissue, ignored the impacts of nonmutated, TKI-unresponsive cancer cells.

274 NSCLC patients were recruited for the study to carry out the mutation analysis and its correlation with the response rate to EGFR TKIs with a novel quantitative methodology.

Experimental Procedures: 1) Selection of paraffin sections of each recruited patients by pathologist to ensure the tumor cells exceeds 70% of total tissue; 2) Extraction of genomic DNA from paraffin sections; 3) Construction of plasmids of both mutated transcripts and wild-type transcripts for each mutation to be analyzed; 4) Real-time PCR amplification of extracted genomic DNA samples with both mutated probes and wild-type probes, and measurement of mutated copy numbers and wild-type copy numbers of each sample with standard curves made by mutated plasmids and wild-type plasmids respectively; 5) Confirmation of the mutation status of each sample with sequencing; 6) Calculation of the percentage of mutated EGFR copy numbers among the total EGFR copy numbers to derive quantitatively mutation data of each patient sample; 7) Observation of EGFR mutations and its demographic features with quantitative data; 8) Evaluation of the outcomes of the therapy with EGFR TKIs (including gefitinib and erlotinib) and analysis of the correlation of increased EGFR mutated transcripts with response rate to EGFR TKIs

Summary of New Data: 1) 94 recruited samples was detected with EGFR mutation among total samples, the mutation ratio various from 5% to 90%; 2) The most frequently detected EGFR mutations among the 94 samples are deletions of Exon 19 (56 cases) and L858R (23 cases); 3) The mutation positive NSCLC patients are divided into 4 groups: a) low mutation rate + gefitinib; b) high mutation rate + gefitinib; c) low mutation ratio + erlotinib; d) high mutation rate + erlotinib. There are significant differences between group a and group b, group c and group d. 4) There is no significant difference between various EGFR mutation types against response rate to TKIs.

Conclusions: 1) The EGFR mutation ratios in NSCLC patients are various; 2) The EGFR mutation ratio is significant correlated with the response rate to TKIs.

This talk is also presented as Poster B36.
Molecular biomarker analyses using circulating tumor cells
Authors: Atwal Siminder K. , Chen Daniel , Lackner Mark , Punnoose Elizabeth
Published: May 2015

Background: Evaluation of cancer biomarkers from blood and other accessible tissues could significantly enable biomarker assessment by providing a relatively noninvasive source of representative tumor material. Circulating tumor cells (CTCs) isolated from blood of metastatic cancer patients hold significant promise in this regard.

Methodology/Principal Findings: Using a tumor-cell spike-in model system we evaluated CTC capture on different CTC technology platforms, including CellSearch® and two biochip platforms, and used the isolated CTCs to develop and optimize assays for molecular characterization of CTCs. We report similar performance for the various platforms tested in capturing CTCs, and find that capture efficiency is dependent on the level of EpCAM expression. We demonstrate that captured CTCs are amenable to biomarker analyses such as HER2 status, qRT-PCR for breast cancer subtype markers, KRAS mutation detection, and EGFR staining by immunofluorescence (IF). We demonstrate that cell surface expression of EGFR can be quantitated in CTCs from metastatic lung cancer patient samples. In addition, we determined HER2 status by IF and FISH in CTCs from metastatic breast cancer patients and in the majority of patients (89%) found concordance with HER2 status from patient tumor tissue, while in a subset of patients (11%), HER2 status had changed from the primary tumor at diagnosis. Surprisingly, we found CTC counts to be higher in ER+ patients in comparison to HER2+ and triple negative patients despite their more aggressive phenotype. This may be explained by our findings that the basal-like molecular subtype of breast cancer has low EpCAM expression and a more mesenchymal phenotype and CTCs will likely not be efficiently captured using EpCAM alone in tumors that arise from this subtype.

Conclusions/Significance: Our data suggests that molecular characterization from captured CTCs is possible and can inform us of the patients’ current biomarker status. In this regard, CTCs hold significant promise as a source of tumor material to facilitate clinical biomarker evaluation. However, limitations exist from a purely EpCAM-based capture system and addition of antibodies to mesenchymal markers in addition to EpCAM could further improve CTC capture efficiency to enable routine biomarker analysis from CTCs.
A RIG-I 2CARD-MAVS200 Chimeric Protein Reconstitutes IFN-β Induction and Antiviral Response in Models Deficient in Type I IFN Response
Authors: Nistal-Villán Estanislao , Rodríguez-García Estefanía , Di Scala Marianna , Ferrero-Laborda Roberto , Olagüe Cristina , Vales África , Carte-Abad Beatriz , Crespo Irene , García-Sastre Adolfo , Prieto Jesús , Larrea Esther , González-Aseguinolaza Gloria
Published: May 2015

RIG-I-like receptors (RLRs) are cellular sensor proteins that detect certain RNA species produced during viral infections. RLRs activate a signaling cascade that results in the production of IFN-β as well as several other cytokines with antiviral and proinflammatory activities. We explored the potential of different constructs based on RLRs to induce the IFN-β pathway and create an antiviral state in type I IFN-unresponsive models. A chimeric construct composed of RIG-I 2CARD and the first 200 amino acids of MAVS (2CARD-MAVS200) showed an enhanced ability to induce IFN-β when compared to other stimulatory constructs. Furthermore, this human chimeric construct showed a superior ability to activate IFN-β expression in cells from various species. This construct was found to overcome the restrictions of blocking IFN-β induction or signaling by a number of viral IFN-antagonist proteins. Additionally, the antiviral activity of this chimera was demonstrated in influenza virus and HBV infection mouse models using adeno-associated virus (AAV) vectors as a delivery vehicle. We propose that AAV vectors expressing 2CARD-MAVS200 chimeric protein can reconstitute IFN-β induction and recover a partial antiviral state in different models that do not respond to recombinant IFN-β treatment.
Epstein-Barr Virus-Positive Pyothorax-Associated Lymphoma Arising from a Posttraumatic Empyema
Authors: Taniguchi Ayuko , Hashida Yumiko , Nemoto Yuiko , Machida Hisanori , Chi SungGi , Ikezoe Takayuki , Yokoyama Akihito , Daibata Masanori
Published: May 2015

Pyothorax-associated lymphoma (PAL) develops from a pyothorax caused by an artificial pneumothorax created during the treatment of pulmonary tuberculosis or tuberculous pleuritis. We report the first case of Epstein-Barr virus (EBV)-positive PAL arising from a posttraumatic empyema. A 75-year-old woman with chronic posttraumatic empyema presented with a tumor, which was connected to the wall of a pyothorax in the right thoracic cavity. She had a history of trauma to the right chest, which had occurred at the age of 45 years and had caused the chronic posttraumatic empyema. Pathological features of the resected tumor were conclusive for a diagnosis of EBV-positive PAL. Although neither postoperative chemotherapy nor radiotherapy was performed, remission was maintained for 3 years until recurrence in the liver. Combination chemotherapy led to complete remission, and 9 years after the initial diagnosis of PAL, the patient is still alive. An intriguing finding is the phenotypic alteration during the disease course. Although the primary tumor was negative for CD20 and CD3, the recurrent tumor expressed both of these molecules. We discuss this case of PAL, which was not a complication of lung tuberculosis, and the aberrant chronological phenotypic change observed in the lymphoma cells, and compare it with a usual case of PAL.
ANCA-Associated Vasculitis in a Patient with Systematic Sclerosis and Sjögren's Syndrome: A Case Report
Authors: Kubota Keiichi , Ueno Toshiharu , Mise Koki , Hazue Ryo , Suwabe Tatsuya , Kikuchi Koichi , Hoshino Junichi , Sumida Keiichi , Hayami Noriko , Takaichi Kenmei , Fujii Takeshi , Ohashi Kenichi , Nonomura Yoshinori , Ubara Yosifumi
Published: May 2015

A 65-year-old woman with a limited form of systematic sclerosis (SSc) and Sjögren's syndrome (SS) was admitted to our hospital for the evaluation of renal dysfunction. Her serum creatinine was 1.6 mg/dl, proteinuria was 1.6 g/day, and the urine sediment contained 20-29 erythrocytes/high-power field. Myeloperoxidase anti-neutrophil cytoplasmic antibodies, anti-SS-A/SS-B antibodies and anti-centromere antibodies were positive. A renal biopsy showed focal necrotizing glomerulonephritis with focal interstitial lymphoplasmacytic infiltration. A diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) was made. A steroid therapy was initiated and AAV subsided. This is a rare case of AAV in a patient with anti-centromere-positive limited SSc and SS.
Jaula de vidro
Authors: Viana Silvia
Published: May 2015

Como novo formato da indústria cultural, os reality shows se tornaram objeto de interesse acadêmico na última década. Das variadas análises a seu respeito, as mais comuns são aquelas voltadas para o interesse gerado em um público ávido pelo obsceno, pelo perverso ou, em sentido lacaniano, por um “acesso imediato ao Real”. Na contramão dessa perspectiva, o presente trabalho busca desenvolver a hipótese segundo a qual tais programas apresentam, em sua forma engessada, não obstante a multiplicação de conteúdos, nossa própria fantasia social. Ou seja, não se trata de uma configuração barrada da cena social, mas daquilo mesmo que a sustenta: nossa reprodução no mundo de trabalho, organizado segundo a acumulação capitalista flexível. O presente ensaio não é uma síntese, mas a reapresentação de algumas das conclusões às quais cheguei em minha pesquisa de doutorado, a respeito de reality shows, realizada junto ao Departamento de Sociologia da USP.
A new species of Boulengerula Tornier (Amphibia: Gymnophiona: Caeciliidae) from an isolated mountain block of the Taita Hills, Kenya
Authors: MÜLLER HENDRIK , MEASEY G. JOHN , LOADER SIMON P. , MALONZA PATRICK K.
Published: May 2015

A new species of East African caeciliid caecilian, Boulengerula niedeni spec. nov. (Amphibia: Gymnophiona) is described based on a series of 11 specimens from Sagalla Hill, an isolated mountain block of the Taita Hills in southern Kenya. It differs from all other Boulengerula, except B. taitanus (Loveridge), in being pigmented with whitish marked annular grooves and from B. taitanus by its distinctive brownish colouration, an exposed sphenethmoid, a higher mean number of annuli and vertebrae, and different phallus morphology.
A new Savignia from Cretan caves (Araneae: Linyphiidae)
Authors: BOSSELAERS JAN , HENDERICKX HANS
Published: May 2015

Savignia naniplopi sp. nov. is described from one male and nine female specimens collected in two adjacent limestone caves in Crete. The taxonomy of the Savignia group of species and the relationships of the new species are discussed.
Genetic relationships of Amaurobioides (Anyphaenidae) spiders from the southeastern coast of New Zealand
Authors: OPELL BRENT D. , BERGER ANDREA M. , BOUS SOPHIA M. , MANNING MICHAEL L.
Published: May 2015

Members of the genus Amaurobioides construct silk retreats in rock crevices of the marine spray zone, a harsh and unusual habitat for spiders. This study expands the distribution records of three morphological species of Amaurobioides found on the eastern and southern coasts of New Zealand's South Island and uses mitochondrial DNA to examine their relationships and characterize their dispersal capabilities. Both 16S and ND1 sequences distinguish A. pletus found on the northeastern coast from a complex of two southern species comprised of A. maritimus from the mainland and A. picunus from Stewart Island. Neither 16S DNA nor ND1 protein separates these southern species. However, ND1 parsimony and likelihood analyses place 10 of 11 Stewart Island specimens in a clade of low support that nests deeply within A. maritimus. A nested haplotype analysis characterizes A. maritimus and A. picunus populations as having restricted gene flow/dispersal but with some long distance dispersal. Genetic distances between A. pletus and the A. maritimus-A. picunus complex indicate a Pliocene origin, whereas distances between A. maritimus and A. picunus suggest a Pleistocene divergence.
Three new species of the genus Ambanus Ovtchinnikov, 1999 from China (Araneae: Amaurobiidae: Coelotinae)
Authors: ZHANG ZHI-SHENG , ZHU MING-SHENG , SONG DA-XIANG
Published: May 2015

Three new species of Ambanus Ovtchinnikov, 1999 (Araneae: Amaurobiidae: Coelotinae) from Mt. Changbai of Northeast China are described: A. pseudonariceus spec. nov., A. triangulatus spec. nov. and A. trisaccatus spec. nov. The study showed that all three new Ambanus species have five to six trichobothria on the retrolateral cymbium, similar to some Coelotinae from the Himalayan region. Draconarius kayasanensis (Paik, 1972) comb. nov. is transferred from Ambanus, and Ambanus nariceus (Zhu & Wang, 1994) comb. nov. from Coelotes.
Two new species of Elacatinus (Teleostei: Gobiidae) from the Mexican coast of the Gulf of Mexico
Authors: TAYLOR MICHAEL S. , AKINS LAD
Published: May 2015

Two new species of gobies (Teleostei: Gobiidae) were recently discovered off the coast of Veracruz, Mexico in the southwestern Gulf of Mexico. Elacatinus jarocho sp. nov. can be diagnosed from other species in the genus by the disjunct yellow lateral stripe restricted to the head and caudal fin base, the yellow medial stripe on the snout, and the black ovoid to rectangular spot at the base of the caudal fin, immediately ventral to the yellow dash. This species forms shoals in the water column close to rock and coral reefs, feeding presumably on zooplankton, a trait shared by only one other species in the genus. Elacatinus redimiculus sp. nov. can be diagnosed from other species in the genus by the distinct reddish orange blotches or broken bands on the head and 13 reddish orange to dark brown stripes between the pectoral and caudal fins. Both species are currently known only from the southwestern Gulf of Mexico from reefs within the Veracruz Marine Park off the coast of Veracruz, Mexico.
Five new species of the genus Tegolophus Keifer (Acari: Eriophyidae: Phyllocoptinae: Anthocoptini) from China
Authors: XUE XIAO-FENG , SONG ZI-WEI , HONG XIAO-YUE
Published: May 2015

In this paper, five new species of the genus Tegolophus Keifer from China are described and illustrated, namely Tegolophus changbais sp. nov. on Ulmus sp. (Ulmaceae); Tegolophus floridumis sp. nov. on Jasminum floridum Bunge (Oleaceae); Tegolophus picrasmae sp. nov. on Picrasma quassioides (D. Don) Benn. (Simarubaceae); Tegolophus suffruticosae sp. nov. on Securinega suffruticosa (Pall.) Rehd. (Euphorbiaceae); Tegolophus triarrhenae sp. nov. on Triarrhena sacchariflora (Maxim.) Nakai (Gramineae). A key to the species of Tegolophus in China is provided. The eriophyoid mite species described here are vagrants on the undersurface of host leaves.
Phylogenetic relationships of Mesoamerican species of the genus Sciurus (Rodentia: Sciuridae)
Authors: VILLALOBOS FEDERICO , CERVANTES-REZA FERNANDO
Published: May 2015

The phylogenetic relationships of Sciurus species present in Mesoamerica are addressed using a morphological analysis under Maximum Parsimony. Our results recovered the existence of two clades: one comprising S. aureogaster, S. colliaei, S. variegatoides and Syntheosciurus brochus and the other clade composed by S. richmondi, S. granatensis, S. deppei, S. yucatanensis and Microsciurus alfari. The taxonomic status of the genera Microsciurus and Syntheosciurus is discussed as well the biogeographic implications of these findings.
Homalometron moraveci n. sp. (Digenea: Apocreadiidae) in the yellowfin goatfish, Mulloidichthys vanicolensis (Valenciennes, 1831) (Perciformes: Mullidae), from New Caledonia and the Great Barrier Reef, with a checklist of digeneans of Mulloidichthys species
Authors: BRAY RODNEY A. , JUSTINE JEAN-LOU , CRIBB THOMAS H.
Published: May 2015

Homalometron moraveci n. sp. is described from the yellowfin goatfish, Mulloidichthys vanicolensis, from the waters off New Caledonia and from the Swain Reefs of the Great Barrier Reef. Its unique combination of narrow, elongate body and long hermaphroditic duct reaching well into the hindbody, distinguish this species from all other species of Homalometron. A checklist of species of digeneans reported in species of Mulloidichthys shows that most of the records are of members of the Opecoelidae and this is the first record of an apocreadiid from this host genus.
Taxonomic status of the genus Spermophilus (Mammalia: Rodentia) in Turkey and Iran with description of a new species
Authors: ÖZKURT ŞAKIR ÖNDER , SÖZEN MUSTAFA , YIĞIT NURI , KANDEMIR IRFAN , ÇOLAK REYHAN , GHARKHELOO MOHAMMED MORADI , ÇOLAK ERCÜMENT
Published: May 2015

We report a new species of Spermophilus ( Rodentia: Sciuridae), here designated as S. torosensis sp. nov., distributed in the Taurus Mountains in southern Anatolia, Turkey. A total of 161 specimens of the genus Spermophilus from Turkey and Iran were analyzed for their morphological, morphometric, and karyological characteristics. Uni- and multi-variate statistical analyses of morphologic data for 95 adult specimens yielded 4 distinct groups. Taxonomic evaluations classified the specimens into 4 species Spermophilus citellus, S. xanthopymnus, S. fulvus and S. torosensis sp. nov. Morphometrics, coat coloration, a brush-shaped tail, and a NFa value of 72 are diagnostic characters that distinguish S. torosensis sp. nov. from the other species. In Turkey, S. torosensis sp. nov. was found in 6 locations. The karyotype of S. fulvus also is described for the first time as 2n= 36, NFa= 70 and NFa= 66; new karyotypic data is reported for S. xanthoprymnus from Iran and Turkey.
New Linyphiidae spiders associated with playas in the Southern High Plains (Llano Estacado) of Texas (Arachnida: Araneae)
Authors: COKENDOLPHER JAMES C. , TORRENCE SHANNON M. , SMITH LOREN M. , DUPÉRRÉ NADINE
Published: May 2015

Three species [Ceratinella playa new species, Erigone denticulata Chamberlin & Ivie, Mermessus denticulatus (Banks)] in the spider family Linyphiidae were associated with emergent vegetation in playa wetlands in the Southern High Plains of Texas. Playa wetlands are being rapidly degraded in the Great Plains of the U. S. A. We describe and illustrate the new species Ceratinella playa from a male and female from Briscoe County, Texas. Erigone denticulata is redescribed and illustrated from males and females from Texas. New distributional records are provided for E. denticulata from the U. S. A.: Colorado, Idaho, Nevada, Oregon, Texas, Utah, and Wyoming. All of these except those from Wyoming are new state records. A new county record of Mermessus denticulatus is reported from Texas.
Phylogenetic analysis of the Paulsoni species group (Decapoda : Alpheidae) from the American Pacific, with implications for the phylogenetic classification of the genus Synalpheus
Authors: HERMOSO-SALAZAR MARGARITA , WICKSTEN MARY , MORRONE JUAN J.
Published: May 2015

A cladistic analysis of 22 species of Synalpheus, represented primarily by species of the Paulsoni species group from the American Pacific and selected species from the Gambarelloides, Neomeris, Brevicarpus, and Biunguiculatus species groups was undertaken, based on 51 morphological characters. The Paulsoni species group proved to be paraphyletic, because species of the Neomeris, Brevicarpus, and Biunguiculatus species groups nested within it. It is proposed herein that in order to achieve a more natural classification, only two groups should be maintained within Synalpheus: Gambarelloides and Paulsoni, the latter in its broadest sense, treating the remaining species groups as synonyms.
Latrunculia (Latrunculia) tetraverticillata sp nov (Porifera, Poecilosclerida, Latrunculiidae) from the bathyal region off the coast of Santa Catarina State, Brazil, Southwestern Atlantic
Authors: MOTHES BEATRIZ , CAMPOS MAURÍCIO , Eckert RAFAEL , LERNER CLÉA
Published: May 2015

Latrunculia (Latrunculia) tetraverticillata sp. nov. is described after two specimens collected off the coast of Santa Catarina State (29 degrees 11'16"S-47 degrees 54'16"W), from a depth of 420 m. The new species differs from the other extant latrunculiid species in having four whorls along the discorhabd axis. A key to the Southwestern Atlantic species of Latrunculia (Latrunculia) is provided.
ICZN rules—a farewell to Tubificidae (Annelida, Clitellata)
Authors: ERSÉUS CHRISTER , WETZEL MARK J. , GUSTAVSSON LENA
Published: May 2015

Morphological and molecular characters support that the former clitellate family Naididae Ehrenberg, 1828 is nested within another family, Tubificidae Vejdovský, 1876. To avoid paraphyly of the latter, it has been suggested that the two should be regarded as a single taxon. A recent decision by the International Commission of Zoological Nomenclature [2007; opinion 2167 (Case 3305)] ruled against a proposed reversal of the nomenclatural priority of Naididae over Tubificidae, with the consequence that all former tubificids should now be regarded as members of the Naididae whenever these two names are regarded as synonyms. The paper is a plea to clitellate researchers to conform to this ruling.
New species of Syphacia (Syphacia) Seurat (Nematoda : Oxyuridae) from Pseudomys species (Rodentia : Muridae) from central Australia
Authors: WEAVER H. J. , SMALES L. R.
Published: May 2015

Syphacia (Syphacia) brevicaudata sp. nov. is described from the desert rodents Pseudomys desertor Troughton, 1936 and P. hermannsburgensis (Waite, 1896); Syphacia (Syphacia) pseudomyos sp. nov. is described from P. hermannsburgensis from western Queensland and central Northern Territory, Australia. Syphacia (Syphacia) brevicaudata is distinguished from all other species of Syphacia by having a suite of characters including an oval, dorsally and ventrally constricted cephalic plate, no cervical alae, a relatively short tail and two pairs of post-anal papillae. Syphacia (Syphacia) pseudomyos is distinguished from all other species of Syphacia by having a suite of characters including an oval, dorsally and ventrally constricted cephalic plate, no cervical or lateral alae, one pair of post-anal papillae, a relatively short tail and large eggs. Females of a putative species were distinct due to the lack of a cephalic plate but had other characters consistent with the genus. Two other putative species of Syphacia, females only, also collected from P. hermannsburgensis and having oval dorsally and ventrally constricted cephalic plates, could be distinguished from their congeners by a combination of characters including the presence of cervical alae, Syphacia sp. 2, and a protruding vulva, Syphacia sp. 3. These new species are the first records of oxyurid nematodes from the genus Pseudomys, and from Australian arid-zone rodents.
A new species of Paramesotriton (Caudata : Salamandridae) from Guizhou Province, China
Authors: ZHAO HAITAO , CHE JING , ZHOU WEIWEI , CHEN YONGXIANG , ZHAO HAIPENG , ZHANG YA-PING
Published: May 2015

We describe a new species of salamander, Paramesotriton zhijinensis, from Guizhou Province, China. The generic allocation of the new species is based on morphological and molecular characters. In morphology, it is most similar to Paramesotriton chinensis but differs in having distinct gland emitting a malodorous secretion (here named scent gland), a postocular stripe, and two non-continuous, dorsolateral stripes on the dorsolateral ridges. Furthermore, neoteny was observed in most individuals of the new species. This has not been previously reported to occur in any other species of Paramesotriton. Analysis of our molecular data suggests that this species a third major evolutionary lineage in the genus Paramesotriton.
A new species of Oratosquillina Manning, 1995 (Crustacea : Stomatopoda : Squillidae) from the Indo-West Pacific region with a key to the genus
Authors: AHYONG SHANE T. , CHAN TIN-YAM
Published: May 2015

A new species of stomatopod crustacean, Oratosquillina nordica sp. nov. is described from the Indo-West Pacific region (type locality: Taiwan). It is most similar to O. quinquedentata (Brooks, 1886), with which it has been confused. Oratosquillina quinquedendata is presently known only from the southern hemisphere, and most of its northern hemisphere records are referable to O. nordica. Records of O. quinquedentata from India and Sri Lanka require confirmation, possibly representing a third species. A key to the species of Oratosquillina is provided.
Cladonema timmsii, a new species of hydromedusa (Cnidaria : Hydrozoa) from a salt lake in South Australia
Authors: GERSHWIN LISA-ANN , ZEIDLER WOLFGANG
Published: May 2015

Cladonema timmsii, sp. nov., is described from Blue Lagoon, an inland saline lake on Eyre Peninsula, near Cactus Beach, due south of Penong, Australia. It is a small medusa with a bell height and diameter of about 2.0mm. It differs from its congeners in having (1) sexually dimorphic gonads, i.e., the males bearing six radially arranged gonadal pouches on the stomach wall, the females lacking gonadal pouches, having instead smooth gonads; (2) different arrangements of nematocyst warts on the main tentacle branches (two rows) and side branches (one row). It is further characterized by having (1) nine simple radial canals, each corresponding with a tentacle bulb bearing a 7-branched stinging tentacle and about six suctorial branches; (2) six oral tentacles with very short stalks, each bearing a terminal nematocyst knob; (3) dark red, lensed ocelli. This is the first report of a species of Cladonema from Australian waters; members of the genus are also reported herein from the Northern Territory and New South Wales.
The crab spiders of the Genus Tmarus from Xishuangbanna, Yunnan, China (Araneae: Thomisidae)
Authors: TANG GUO , LI SHU-QIANG
Published: May 2015

Four new and three known crab spider species of the genus Tmarus are reported from the Xishuangbanna Rainforest of Yunnan, China: T. byssinus sp. nov., T. hastatus sp. nov. male only), T. spicatus sp. nov. (female only), T. undatus sp. nov. (female only), T. menglae Song and Zhao, 1994, T. songi Han and Zhu, 2008 and T. taiwanus Ono, 1977. The male of T. menglae is described for the first time. The type specimens are deposited in the Institute of Zoology, Chinese Academy of Sciences in Beijing.
Overview of Candoninae (Crustacea, Ostracoda) of South America and the West Indies, with the description of two new species and one new genus
Authors: KARANOVIC IVANA , DATRY THIBAULT
Published: May 2015

The present paper contains descriptions of two new species and one new genus: Latinopsis patagonica gen. nov., sp. nov., and Candona quasiincarum sp. nov. Both species were collected during a two-month Franco-Chilean expedition to Madre de Dios archipelago in January and February 2006. The following new systematic arrangements are proposed: L. anisitsi (Daday, 1905) comb. nov., L. columbiensis (Mehes, 1914) comb. nov., and L. falclandica (Vavra, 1898) comb. nov. Latinopsis anisitsi is redescribed from the type material and a lectotype is designated. Two species are excluded from the subfamily Candoninae, one of which is Danielocandona albida (Sars, 1901). After examination of the type material the species is reclassified as Neocypridopsis albida (Sars, 1901) comb. nov. A checklist of the known species of Candoninae of South America and the West Indies is provided.
A revision of the genus Medmassa Simon, 1887 (Araneae: Corinnidae) in the Afrotropical Region
Authors: HADDAD CHARLES R. , BOSSELAERS JAN
Published: May 2015

The genus Medmassa Simon, 1887 is revised in the Afrotropical Region. The type species is M. frenata (Simon, 1887) from the Philippines, described from a subadult female. The widespread, but previously poorly known M. semiaurantiaca Simon, 1910, appears to be the only congeneric Afrotropical species. It is redescribed, illustrated for the first time, and proposed as a senior synonym of M. hiekae Berland, 1922. Medmassa laurenti Lessert, 1946 from the Congo D. R. is proposed as a junior synonym of Mandaneta sudana (Karsch, 1880). Medmassa lesserti Strand, 1916 from the Congo D. R. is transferred to Procopius Thorell, 1899 and proposed as a senior synonym of Procopius quaerens Lessert, 1946. Medmassa nitida Lawrence, 1942 from South Africa is proposed as a junior synonym of Pronophaea natalica Simon, 1897. Medmassa proxima Lessert, 1923 and M. vidua Lessert, 1923, also from South Africa, are misplaced and their transfer to Pronophaea Simon, 1897 is proposed. The female holotype of M. nyctalops Simon, 1910 from the island of Bioko is lost and this species is considered nomen dubium. M. semiaurantiaca is recorded from Botswana, Central African Republic, Congo D. R., Ethiopia, Ghana, Guinee-Bissau, Kenya and South Africa. Field observations indicate that it is a fast-running nocturnal hunter that forages on the bark of trees, with a preference for those with smooth bark. Most of the material was collected by canopy fogging or active searching at night.
A new species of the Genus Euscorpiops Vachon, 1980 (Scorpiones: Euscorpiidae, Scorpiopinae) from Yunnan, China
Authors: DI ZHI-YONG , CAO ZHI-JIAN , WU YING-LIANG , LI WEN-XIN
Published: May 2015

A new species of scorpion, Euscorpiops validus sp. nov. (Euscorpiidae) is described from Honghe Prefecture, Yunnan Province, China. The new species can be characterized by having 18 (rarely 17) external trichobothria (5 eb, 2 esb, 2 em, 4 est, 5 et), and 9 or 10 (rarely 8 or 11) ventral trichobothria in the pedipalp patella; a pair of strong chela with a length/width ratio average of 3.0 on males and 3.1 on females; chela fingers strongly curved; cheliceral movable fingers with 6 or 7 (rarely 4 or 5) basal teeth on ventral edge; and pectinal fulcra present.
A new Alboglossiphonia species (Hirudinea: Glossiphoniidae) from Egypt: Description and life history data
Authors: GOUDA HANAA A.
Published: May 2015

A new glossiphoniid leech was collected from Assiut, Egypt. Both external morphology and internal anatomy have been examined. Alboglossiphonia levis n. sp. is placed in the genus Alboglossiphonia under the disjuncta-group on the basis of having three pairs of eyes, diffuse salivary cells, seven pairs of crop caeca and the eggs are attached directly to the venter of the parent. The new species, as most of species of the genus Alboglossiphonia, revealed a combination of the following characters; its greenish color, seven pairs of branchiate crop caeca and the gonopores are separated by two annuli, but it is characterized by the absence of papillae on the body surface and presence of four pairs of testisacs. The life history of A. levis was studied in the laboratory. Hatching occurred within 10–15 days of laying egg and the hatchlings were attached to the parent's venter by their posterior suckers. After another four weeks, young could leave their parent, grew and matured. Four months old leeches are able to lay eggs. The leech reproduces once during its life history in the laboratory which takes about six months. A. levis displayed well developed parental care where the parent protects their young and also feeds them. Feeding and other ecological observations were described.
Bathykorus bouilloni: a new genus and species of deep-sea jellyfish from the Arctic Ocean (Hydrozoa, Narcomedusae, Aeginidae)
Authors: RASKOFF KEVIN A.
Published: May 2015

A new genus and species of a common deep-water narcomedusa is described from the Arctic Ocean. The species has four primary tentacles, four secondary tentacles, with three interradial manubrial pouches in each quadrant. A revision and taxonomic key of the family Aeginidae is presented to account for the new genus. Detailed information on its fine-scale vertical and horizontal distributions show that it occurs in a fairly narrow depth range between 1400–2000 meters. The species was observed 423 times at eleven stations, demonstrating that new species can be common in the under-explored regions of the ocean.
Early larval morphology of the armed nylon shrimp Heterocarpus ensifer ensifer A. Milne-Edwards, 1881 (Decapoda, Caridea, Pandalidae) from laboratory culture
Authors: LANDEIRA JOSÉ MARÍA , LOZANO-SOLDEVILLA FERNANDO , ALMANSA EDUARDO , GONZÁLEZ-GORDILLO JUAN IGNACIO
Published: May 2015

The first four zoeal stages of the shrimp Heterocarpus ensifer ensifer were obtained under laboratory conditions. The morphology of each larval stage was described and illustrated in detail. The Heterocarpus's larval features fit into the characteristics of the family Pandalidae, and indicate a close relationship with the genus Plesionika.
High-resolution X-ray computed tomography of an extant new Donuea (Araneae: Liocranidae) species in Madagascan copal
Authors: BOSSELAERS JAN , DIERICK MANUEL , CNUDDE VEERLE , MASSCHAELE BERT , VAN HOOREBEKE LUC , JACOBS PATRIC
Published: May 2015

A new extant Donuea (Liocranidae) species is described from Madagascar, from both alcohol preserved fresh material and also as a subfossil in copal from the Sambava area. X-ray micro computed tomography was used to visualise minute details of the male palp of the copal specimen in order to confirm conspecificity. This is the first time a new spider species discovered in Madagascan copal can immediately be demonstrated as belonging to an extant species.
Multitestis Manter 1931 (Digenea: Lepocreadiidae) in ephippid and chaetodontid fishes (Perciformes) in the south-western Pacific Ocean and the Indian Ocean off Western Australia
Authors: BRAY RODNEY A. , CRIBB THOMAS H. , JUSTINE JEAN-LOU
Published: May 2015

Five species of the genus Multitestis are described, figured or discussed: Multitestis pyriformis from Platax orbicularis off Lizard Island, northern Great Barrier Reef, Australia and Platax teira off New Caledonia; Multitestis coradioni n. sp. (syn. Multitestis pyriformis Machida, 1963 of Bray et al. (1994)) from Coradion chrysozonus off Heron Island, which differs from M. pyriformis in its oval body-shape, the more posteriorly situated testicular fields and larger eggs, Multitestis elongatus from Platax pinnatus off Lizard Island, Multitestis magnacetabulum from P. teira off Heron Island, southern Great Barrier Reef, Australia, and New Caledonia, Multitestis paramagnacetabulum n. sp. from P. orbicularis off Ningaloo Reef, Western Australia, which differs from M. magnacetabulum in the more posteriorly situated testicular fields.
Petroleuciscus esfahani, a new species of fish from central Iran (Actinopterygii: Cyprinidae)
Authors: COAD BRIAN W. , BOGUTSKAYA NINA G.
Published: May 2015

A new species, Petroleuciscus esfahani, is described from central Iran in the Zayandeh River basin. It is distinguished from other members of the genus by a combination of characters including a mode of 8 1/2 dorsal-fin branched rays, modally 10-11 1/2 anal-fin branched rays, small scales numbering 44-54 in the total pored lateral line, a modal pharyngeal-tooth formula 2.5-4.2, and total vertebrae usually 40-42. It appears to be morphologically closest to Petroleuciscus gaderanus (Gunther, 1899) that we tentatively consider as a synonym of P. ulanus (Gunther, 1899) of the Lake Orumiyeh basin in northwestern Iran.
Peckoltia compta, a new species of catfish from the Brazilian Amazon, rio Tapajos basin (Siluriformes: Loricariidae)
Authors: DE OLIVEIRA RENILDO RIBEIRO , ZUANON JANSEN , PY-DANIEL LUCIA RAPP , ROCHA MARCELO SALLES
Published: May 2015

The loricariid genus Peckoltia currently encompasses 13 valid species ranging throughout the Amazon basin in Brazil, Venezuela, Colombia, Peru, and Guyanas. Peckoltia is included in the tribe Ancistrini, but its relationships with other taxa within the tribe are not well established. In this paper we describe a new species of Peckoltia from the rio Tapajos drainage, Para State, Brazil. Peckoltia compta, new species, is characterized by a bold color pattern consisting of large dark transversal bars on body and thick longitudinal dark stripes on snout and head. The new species is most similar in color pattern to P. vittata but can be distinguished from all its congeners by the presence of a pale line inside each dark stripe running from the snout tip to anterior margin of eyes (vs. absence of such clear lines and a mottled appearance in P. vittata, and a mix of vermiculations and spots on the head of the remaining congeners). A brief discussion on the taxonomic status of the nominal species Peckoltia vittata is also presented.
Priority of Geranoaetus Kaup, 1844 over Tachytriorchis Kaup, 1844 (Aves: Accipitridae) based on the first reviser principle
Authors: DO AMARAL FÁBIO RAPOSO , SHELDON FREDERICK H. , GAMAUF ANITA , HARING ELISABETH , RIESING MARTIN J. , SILVEIRA LUÍS F. , WAJNTAL ANITA
Published: May 2015

The generic name Geranoaetus Kaup, 1844 (type species: Falco aguia Temminck = Spizaetus melanoleucus Vieillot) generally has been applied only to its type species, G. melanoleucus, although inclusion of fossil species in the genus has been suggested (Wetmore 1933; Amadon 1963). Although Geranoaetus is still recognized by some authors (e.g., Thiollay 1994; Remsen et al. 2010), others consider it a junior synonym of the genus Buteo Lacépedè, 1799, because of similarities to some species in that genus (e.g., Wetmore 1933; Hellmayr & Conover 1949; Clark 2006). Recent studies of the molecular phylogenetics of buteonine hawks (Riesing et al. 2003; Lerner et al. 2008; Amaral et al. 2006, 2009) unanimously agree on the lack of monophyly of three buteonine genera, namely Buteo, Leucopternis Kaup, 1847 and Buteogallus Lesson, 1830, as currently recognized (Remsen et al. 2010).
The taxonomic research of Jules Richard on Cladocera (Crustacea: Branchiopoda) and his collection at the National Museum of Natural History, USA
Authors: KOTOV ALEXEY A. , FERRARI FRANK D.
Published: May 2015

Jules Richard (1863-1945) contributed significantly to cladoceran taxonomy before he became Director of the Musee Oceanographique de Monaco and assistant to Prince Albert I-er de Monaco. His collection, including slides and samples preserved in ethanol, was purchased by E. A. Birge, subsequently incorporated into the collection of David G. Frey, and later gifted to the National Museum of Natural History, Smithsonian Institution. A list of publications of Richard about cladocerans is presented, as well a list of all new taxa described by him (three genera and 37 taxa of species rank), with information about type localities, synonymies and taxonomic comments. Lectotypes and in some cases paralectotypes are selected for Daphnia (Ctenodaphnia) bolivari Richard, 1888; D. (Daphnia) curvirostris insulana Moniez in Richard, 1896; Bosmina japonica Poppe & Richard, 1890; Grimaldina brazzai Richard, 1892 and Alona sarsi Richard, 1891. Syntypes exist for Alona moniezi Richard, 1888 and Pleuroxus letourneuxi (Richard, 1888). The ethanol samples of Richard that may contain species for which there are no types are discussed. In addition, samples in the collection of David G. Frey from type localities of Richard's species are noted. These samples could be important for future revisions of the Richard's taxa. A redescription of Pleuroxus letourneuxi (Chydoridae, Chydorinae) is given; Bosmina japonica Poppe & Richard, 1890 (Bosminidae), a junior synonym of B. longirostris (O. F. Muller, 1776), also is redescribed.
Papakula and Hesydrimorpha: how two spider genera were described from the same species collected from the same locality (Araneae: Pisauridae)
Authors: JÄGER PETER
Published: May 2015

While identifying Pisauridae from Laos and checking various genera of this family from Southeast Asia, two monotypic genera were striking: Hesydrimorpha Strand 1911 and Papakula Strand 1911. Both were described by Strand (1911) from Eastern Indonesia and the type material was deposited in the Senckenberg Museum (SMF). They were recorded from the same island (Kobroor) and the same locality (Papakoela, Papakula). The labels and original descriptions state they were collected by H. Merton. Strand (1911) also mentioned in the publication that the specimens were collected in a house, most likely the same house, as Merton collected both series on the same day.
Draposa, a new wolf spider genus from South and Southeast Asia (Araneae: Lycosidae)
Authors: KRONESTEDT TORBJÖRN
Published: May 2015

Draposa gen. nov. is proposed for eight wolf spider species from the Indomalayan Region, all of which were previously placed in the genus Pardosa: Draposa atropalpis (Gravely, 1924) comb. nov., D. lyrivulva (Bosenberg & Strand, 1906) comb. nov. (= Pardosa leucopalpis Gravely, 1924 syn. nov.), D. nicobarica (Thorell, 1891) comb. nov., D. oakleyi (Gravely, 1924) comb. nov., D. porpaensis (U. A. Gajbe, 2004) comb. nov., D. subhadrae (Patel & Reddy, 1993) comb. nov., D. tenasserimensis (Thorell, 1895) comb. nov., and D. zhanjiangensis (Yin, Wang, Peng & Xie, 1995) comb. nov. Species of Draposa share synapomorphies in the copulatory organs, inter alia a complex subpaleal sclerite in the terminal part of the male bulbus. The presence of D. lyrivulva in Japan is put in doubt and the species should be excluded from the list of spiders in that country. Draposa nicobarica (type species) and D. tenasserimensis are redescribed and illustrated for the first time from the type material. Draposa atropalpis is redescribed from material from India and Sri Lanka, D. lyrivulva and D. subhadrae (first record outside India) from material collected in Sri Lanka and D. oakleyi from material from India and Bangladesh.
Checklist of the parasites of the black-necked swan, Cygnus melanocoryphus (Aves: Anatidae), with new records from Chile
Authors: GONZÁLEZ-ACUÑA DANIEL , MORENO LUCILA , CICCHINO ARMANDO , MIRONOV SERGEY , KINSELLA MIKE
Published: May 2015

Black-necked swans (Cygnus melanocoryphus) are endemic to the southern cone of South America. Their range extends from Brazil and Paraguay south to Argentina and Chile. A total of 16 parasite species were collected from 7 swans from the Biobio region, Chile, of which 12 are new records for Chile and 11 represent new host records, Echinostoma trivolvis, Paranomostomum sp., Microsomacanthus sp., Nadejdolepis sp., Retinometra sp., Avioserpens sp., Capillaria skrjabini, Ingrassia cygni, Anatoecus penicillatus, A. icterodes and A. keymeri. A checklist is presented that summarizes sites of infections, localities, life cycles and their intermediate hosts (if known), and the pertinent references to demonstrate the wide diversity of parasites of black-necked swans. Our review of the existing literature (23 publications) along with our own records provided information on a total of 18 families and 27 genera, including 33 described species (some only identified to genus), of which 11 were recorded only in Chile (8 endoparasites and 3 ectoparasites), and 6 only in Argentina (4 endoparasites and 2 ectoparasites). Five parasites are known only from captive swans in European zoos. Parasites recorded from C. melanocoryphus include 23 helminths and 10 ectoparasites (one leech and 9 arthropods).
Clubionidae from Laos and Thailand (Arachnida: Araneae)
Authors: JÄGER PETER , DANKITTIPAKUL PAKAWIN
Published: May 2015

Clubionidae collected in Laos and Thailand were investigated. Seven new species are described: Clubiona kai spec. nov. (male: Laos, Luang Prabang Prov.), Clubiona lala spec. nov. (female: Laos, Luang Nam Tha Prov.), Clubiona maipai spec. nov. (male: Thailand, Mae Hong Son Prov.), Clubiona kuu spec. nov. (male: Laos, Luang Prabang Prov.), Clubiona vukomi spec. nov. (male: Laos, Luang Nam Tha Prov.), Malamatidia zu spec. nov. (male: Laos, Luang Prabang Prov.) and Malamatidia christae spec. nov. (female: Laos, Luang Nam Tha Prov.). The genus Malamatidia, previously known from Sumatra, Sarawak, the Malaysian peninsular, Kalimantan, and Sulawesi is recorded from Laos (Luang Nam Tha Province) as northernmost distribution locality and is re-diagnosed. Cheiracanthium insulanum (Thorell, 1878), Cheiracanthium unicum Bosenberg and Strand, 1906, Clubiona abnormis Dankittipakul, 2008, Clubiona filicata O. Pickard-Cambridge, 1874, Clubiona melanothele Thorell, 1895 are recorded for the first time from Laos. Cheiracanthium insulanum, Clubiona abnormis, and Clubiona melanothele are additionally illustrated. A map with all records is provided.
Two new species of the spider genus Cataleptoneta from Balkan Peninsula (Araneae, Leptonetidae)
Authors: WANG CHUNXIA , LI SHUQIANG
Published: May 2015

Two new species of the spider family Leptonetidae from caves of Balkan Peninsula are diagnosed, described, and illustrated, i.e., Cataleptoneta lingulata sp. nov. from Northern Dalmatia, Croatia, and Cataleptoneta semipinnata sp. nov. from Island Kythira, Greece.