bluuebunny/crossref_metadata_2025 huggingface dataset:
An Experimental Investigation on Mechanical Properties of High Strength Performance Concrete using GGBS and Alccofine
Authors: B. Harish  , P. Renuka  , P. Renuka  , I. Sunitha  , I. Sunitha
Published: September 2022

The necessity of high performance concrete is increasing because of the increasing demand of the construction materials in the construction industry. Efforts for improving the performance of concrete over the past few years suggest that cement replacement materials along with Mineral & chemical admixtures can improve the strength and durability characteristics of concrete. This project is an attempt to study the behaviour of Alccofine 1203 (5%, 6%, 7%, 8% and 10% replacement by weight of cement) along with Fly Ash (15%) and GGBS (15%) replacement on fresh & hard property of concrete. As well as optimizing the percentage dosage of chemical admixture to achieve required retention period (up to 3hrs) and workability (Slump and Flow) to increase the productivity of concrete design. This paper also studies the effectiveness of applying value engineering to actual concrete mixtures. The application of value engineering to such concrete mixtures results in increase in performance, optimizing the mix by adding appropriate dosage of admixtures so as to work in different situation and increase its value, increase in durability of structure in which concrete will be used, reduction in cost of concrete and overall cost of construction projects, increasing the market share and competitiveness of concrete producers. This research shows that applying the methodology of value engineering to readymixed concrete is an effective way to save around 7.5-8.5 % of the total cost of concrete mixtures supplied to construction projects..
Design of Earthquake Resistance on Residential Building by using STAADPRO
Authors: P. Shivashanker  , Ch. Geetha  , S. Thirupathi  , K. Uma  , Md. Athar
Published: September 2022

In India, multi-storied buildings are usually constructed due to high cost and scarcity of land. In order to utilize maximum land area, builders and architects generally propose asymmetrical plan configurations. These asymmetrical plan buildings, which are constructed in seismic prone areas, are likely to be damaged during earthquake. Earthquake is a natural phenomenon which can generate the most destructive forces on structures. Buildings should be made safe for lives by proper design and detailing of structural members in order to have a ductile form of failure. The concept of earthquake resistant design is that the building should be designed to resist the forces, which arises due to Design Basis Earthquake, with only minor damages and the forces, which arises due to Maximum Considered Earthquake, with some accepted structural damages but no collapse. This project report comprises of seismic analysis and design of an eight-storied R.C. building with asymmetrical plan. The building is modelled as a 3D space frame with six degrees of freedom at each node using the software STAAD PRO V8I v 14.2.4. Building is analyzed using Response Spectrum method. The Response Spectra as per IS 1893 (Part 1): 2002 for rocky or hard soil is used.
Vehicle Followed Street Light Controlling using Arduino
Authors: G Kumaraswamy G  , Jagan D  , Snehith B  , A Rajitha Reddy  , Rohithraj
Published: September 2022

Automation plays an increasingly very important role in the world economy and in daily life. Automatic systems are being preferred over any kind of manual system. We can also call it an “SMART STREET LIGHT SENSING”. Intelligent light sensing refers to public street lighting that adapts to movement by pedestrians, cyclists and cars. Intelligent street lighting, also referred to as adaptive street lighting, dims when no activity is detected, but brightens when movement is detected. This type of lighting is different from traditional, stationary and illumination, or dimmable street lighting that dims at predetermined times. The research work shows automatic control of streetlights as a result of which power is saved to some extent. In the scope of industrialization, automation is a step beyond mechanization. Whereas mechanization provided human operators with machinery to assist the users with muscular requirements of work, automation greatly decreases the need for human sensory and mental requirements as well. Basically, street lighting is one of the important parts. Therefore, the street lamps are relatively simple but with the development of urbanization, the number of streets increases rapidly with high traffic density.
PLC and SCADA Based Classroom Automation in the College
Authors: Dr. B. Veeru  , Mrs. T. Amani  , B. Gowardhan  , Mrs. E. Ranuka  , D. Tulasi
Published: September 2022

In the project we are making class rooms automatized by using plc and scada system. In the class room the lights and fans are getting ON/off when someone in class room, otherwise it would be off, so that we can avoid the unnecessary lights and fans ON, and can save electricity. In one class room we are fixing 4 motion sensors in different area, so that it would give signal to plc, if any person will come to the particular area and then plc will ON the fans or lights. The total process would be monitored & controlled from scada system. Anything customize from scada system & control the process.
Study on Evaluation of Strength Properties on Geopolymer Concrete with Different Combinations of Pozzolonic Materials
Authors: G. Rajesh  , P. Shivashanker  , Radhika  , Radhika  , Sonia
Published: September 2022

Geo-polymer concrete is totally different in materials and chemistry which is synthesized from waste material like fly-ash (Class F or C), rice husk along with binding solution which is free of cement. This paper gives an overall view of the process and parameters which effect the geo-polymer concrete till date. It is an inorganic 3D polymer which is synthesized by activation of aluminosilicate source like fly ash or GGBS (waste materials). Due to its high mechanical properties combined with substantial chemical resistance (magnesium or sulphate attack), low shrinkage and creep and environment friendly nature (very less amount of CO2 production in comparison with OPC), it is a novel construction material for future. Till date it was seen that the strength of geo-polymer concrete mostly depends on the molarities of the alkaline liquid NaOH& Na2SiO3 (are used for binding of materials.). It was seen that geo-polymer concrete made of fully Fly-ash or partial replacement by GGBS results with 80% reduction in CO2 emission compared to OPC, although the alkaline solution to some extent pollutes the environment.
Structural Behaviour of Hybrid Fiber Reinforce Concrete by Using Steel and Polypropylene Fiber
Authors: T. Naresh  , G. Rajesh  , M. Shashivarrao  , B. P. Syiemlish  , G. Nithish
Published: September 2022

Hybrid fiber reinforced concrete can be defined as concrete that reinforced by two or more types of fibers. This study aims to study the mechanical properties of hybrid fiber reinforced concrete where the fibers used were consists of steel fiber and polypropylene fiber. For this purpose five mixes, one normal control mix and four hybrid fiber reinforced concrete mixes were prepared. The volume of steel and polypropylene fiber is kept content from 0.0 to 1%. Slump Test was carried out for each mix in the fresh state in order to determine the workability of the hybrid fiber reinforced concrete. Meanwhile, compressive test, flexural test and split tensile test were carried out to study the mechanical properties of the hybrid fiber reinforced concrete. From the slump test all specimens show low workability. For the result of Compressive split tensile and Flexural Test, the normal control mix shows normal strength development but all the hybrid fiber reinforced concrete mixes gain their strength higher the normal control mix. The expected outcome which is the strength of hybrid fiber reinforced concrete is higher than the strength of normal concrete did achieved. So, further research need to be carried out with some adjustments of methods or materials.
Brain Tumour Image Segmentation Using Deep Networks
Authors: Y. Ganesh  , G. Anitha  , CH. Saritha  , L. Mohan  , Divyavani
Published: September 2022

Automated segmentation of brain tumour from multimodal MR images is pivotal for the analysis and monitoring of disease progression. As gliomas are malignant and heterogeneous, efficient and accurate segmentation techniques are used for the successful delineation of tumours into intra-tumoural classes. Deep learning algorithms outperform on tasks of semantic segmentation as opposed to the more conventional, context-based computer vision approaches. Extensively used for biomedical image segmentation, Convolutional Neural Networks have significantly improved the state-of-the-art accuracy on the task of brain tumour segmentation. In this paper, we propose an ensemble of two segmentation networks: a 3D CNN and a U-Net, in a significant yet straightforward combinative technique that results in better and accurate predictions. Both models were trained separately on the BraTS-19 challenge dataset and evaluated to yield segmentation maps which considerably differed from each other in terms of segmented tumour sub-regions and were ensembled variably to achieve the final prediction. The suggested ensemble achieved dice scores of 0.750, 0.906 and 0.846 for enhancing tumour, whole tumour, and tumour core, respectively, on the validation set, performing favourably in comparison to the state-of-the-art architectures currently available.
Design and Implementation of Elevator Controller using Verilog
Authors: P. Thiripathi  , D. Sravani  , Dharmendar B  , Kalyan  , Gongalla Mounika
Published: September 2022

In this cutting-edge period, lifts have turned into a basic piece of any business or open complex. It encourages the quicker development of individuals and gear between floors. The lift control framework is a standout amongst the most critical perspectives in hardware control module that are utilized as a part of car application. Normally lifts are intended for a particular building considering the fundamental factors, for example, the tallness of the building, the quantity of individuals venturing out to each floor and the normal times of high utilization. The lift framework is composed with various control procedures. This usage depends on FPGA, which can be utilized for a working with any number of floors, with the predetermined sources of info and yields. This controller can be executed for a lift with the required number of floors by just changing a control variable in the HDL code. This approach depends on a calculation which decreases the measure of calculation required, by concentrating just on the pertinent guidelines that enhances the execution of the gathering of lift framework.
Cyber Bullying Detection based on Semantic-Enhanced Marginalized De noising Auto-Encoder
Authors: Mrs. P Renuka  , Dr. M V Bramhananda  Reddy  , Mr. Chelloju Raju  , Mrs. Gudelli Archana  , Mrs. Aruri Vyshali
Published: September 2022

As a side effect of increasingly popular social media, cyber bullying has emerged as a serious problem afflicting children, adolescents and young adults. Machine learning techniques make automatic detection of bullying messages in social media possible, and this could help to construct a healthy and safe social media environment. One critical issue is robust and discriminative numerical representation learning of text messages. In this, we propose a new representation learning method to tackle this problem. Our method named Semantic-Enhanced Marginalized Denoising Auto-Encoder (smSDA) is developed via semantic extension of the popular deep learning model stacked denoising autoencoder. The semantic extension consists of semantic dropout noise and sparsity constraints, where the semantic dropout noise is designed based on domain knowledge and the word embedding technique. Our proposed method is able to exploit the hidden feature structure of bullying information and learn a robust and discriminative representation of text.
Prospects for the use of leaf-stem biomass of the Southern reed for the treatment of water bodies
Authors: Sokolova Natalya , Khlobzheva Inna , Vasenev Ivan , Kostin Vasily , Kochetkov Vladimir , Gamaga Varvara
Published: September 2022

The article is devoted to the actual environmental problem of cleaning water bodies. The authors studied the properties of new sorbents obtained from crushed leafy biomass of the southern reed (Phragmites australis) and their use in the pollution of water bodies by accidental oil spills and oil products. Information about the most common cellulose-containing sorbents used to clean up oil spills is given. The prospects of using sorbents based on crushed and carbonized leafy biomass of southern reed (Phragmites australis) for cleaning water bodies are shown. Keywords: PLANT RAW MATERIALS, CELLULOSE-CONTAINING SORBENTS, LEAF BIOMASS, OIL CAPACITY, ADSORPTION ACTIVITY, WATER POLLUTION, ENVIRONMENTAL CONSEQUENCES, SOUTHERN REED (PHRAGMITES AUSTRALIS)
Planning Pedestrian Paths for Trade and Service Areas of Balikpapan City with the Walkability Concept
Authors: Kumandang Enggal Muluk , Tufail Dwiana Novianti
Published: September 2022

Corridor of the commercial area of Jalan MT. Haryono Balikpapan City specifically from the MT. Haryono Bridge to the Traffic Light Beruang Madu Monument has the characteristics of high mobility by motorized vehicles. Under these conditions, efforts are needed to encourage non-motorized movements. One of the efforts that have been made in the provision of pedestrian paths in the trade and service area. However, the lane has several problems, such as damaged sidewalks, motorized vehicles that often park around the sidewalks, and there are no guiding blocks for disabled users. Therefore, this study aims to plan a pedestrian path in the commercial area in the corridor of Jalan MT. Haryono uses the concept of walkability. This research uses walkability suitability analysis, community satisfaction level analysis, and Photo Mapping analysis. The results of the suitability analysis showed that segment 1 of the research area was not following the walkability and it was necessary to improve the pedestrian path infrastructure and add supporting facilities such as chairs, trash cans, CCTV, and shade plants, to guide blocks. While in segment 2, almost all of the variables are appropriate and require maintenance of several pedestrian path facilities. In the analysis of the level of community satisfaction using the Multicriteria Satisfaction Analysis, the planning priorities of the 4 walkability indicators are obtained. The results of this analysis show that segment 1 requires planning for the development of safety and comfort indicators, while segment 2 requires planning related to the development of safety and beauty indicators. The results of Photo Mapping show that it is necessary to add road barrier facilities, guiding blocks, parking ban signs, resting chairs, green lanes, repairing pedestrian lane infrastructure, and improving zebra crossing in segment 1. Segment 2 requires additional parking ban markers, speed bumps, chairs, trash cans, green paths, and care for weeds growing along the walkways
SPECIES DIVERSITY AND COMMUNITY STRUCTURE OF BEACH FORESTS IN SAN FERNANDO, SAN JOSE, ANTIQUE, PHILIPPINES
Authors: Millamena Aljim G. , Daylusan, Ferlyn A. , Alian Diane Claire H. , Sansait May M. , T.MALABARBAS GERALD
Published: September 2022

Beach forests play a vital role in disaster mitigation and climate change mitigation. These forests protect coastal communities against natural calamities. It has been observed that areas with less or absence of beach forests and mangrove systems were highly devastated compared to those with. However, these ecosystems were neglected due to lesser studies and baseline information about the species diversity and community structure and its role in the overall ecology of the area. The study assessed the species diversity and community structure of beach forests in San Fernando, San Jose, Antique, Philippines. The study used the transect line plots method in an area that was purposively selected. The general floristic composition was based on an ocular survey of the selected site. Characterization of community structure was done using accepted parameters.  Results showed a total of sixteen (16) beach forest species that belong to twelve (12) families. Tabernaemontana pandacaqui and Jatropha gossypifolia were found to be the most frequently occurring species. The plant diversity of the area is low (mean H’ = 0.968) which is attributed to anthropogenic disturbances. The species with the highest Importance Value was Capparis micracantha (IV =61.02). Overall, beach forest in San Fernando, San Jose has a high species evenness (J’ = 0.929) which proves that conservation and preservation efforts must be increased. It is recommended that local government units must develop plans to promote awareness and strengthen values for conservation and protection of the beach forests among its people.
Keywords: Beach Forest, Forest Conservation, Biodiversity, Importance Value.
Tingkat Pengetahuan Remaja Tentang Pelecehan Seksual di MTs NW Mataram
Authors: Supiana Nia , Musrifa Musrifa , Hidayati Nurul
Published: September 2022

Kasus pelecehan Seksual yang dialami remaja semakin meningkat dengan pengetahuan para remaja yg sangat minim. Tujuan penelitian ini adalah untuk mengetahui Tingkat Pengetahuan Remaja Terhadap Pelecehan Seksual di MTs NW Mataram Tahun 2018. Pelecehan Seksual adalah perilaku atau tindakan yang menjengkelkan dilakukan seseorang terhadap pihak lain, yang berkaitan dengan jenis kelamin.dan dirasakan menurunkan martabat dan harkat diri yang di ganggunya. (Suryati,2009).Metode penelitian dalam penelitian ini adalah deskriftif. Populasinya adalah seluruh siswa kelas VII dan VIII  yang sekarang menjadi kelas VIII dan IX sebanyak 72 orang yang ada di MTs NW Mataram. Teknik pengambilan sampel dalam penelitian ini adalah sampel jenuh sehingga semua populasi di jadikan sampel sebanyak 72 orang . alat bantu yang digunakan adalah kueisioner.

Hasil penelitian menunjukan bahwa dari 72 orang yang ada di Mts.NW Mataram menunjukan bahwa sebagian besar remaja memiliki pengetahuan yang cukup tentang pelecehan seksual sebanyak 39 orang (54,2 %) kurang 19 orang (26,4%) dan yang baik 14 orang (19,4%).

Kesimpulan dalam penelitian ini bahwa dari 72 remaja yang diteliti di MTs NW Mataram sebagian besar memiliki pengetahuan yang cukup sebanyak 39 orang (54,2%)

Disarankan kepada pihak sekolah yang ada di MTs NW Mataram, agar hasil penelitian ini dapat dijadikan sebagai sumber informasi yang lebih banyak tentang pelecehan seksual kepada siswa dan siswi untuk meningkatkan pengetahuan siswa dan siswi tentang pelecehan seksual dengan melakukan kerja sama dengan petugas kesehatan untuk melakukan penyuluhan agar penyampaiannya lebih jelas serta dianjurkan untuk mengadakan program penyuluhan kesehatan reproduksi dan menyediakan kurikulum tentang kesehatan reproduksi.
Pengetahuan Ibu Tentang Perubahan Psikologis Masa Menopause di Puskesmas Ampenan
Authors: Hidayati Nurul , Munawarah Ziadatul , Bajri Reza Anastasia
Published: September 2022

Berdasarkan hasil studi pendahuluan yang telah dilakukan peneliti di Puskesmas Ampenan menunjukkan bahwa dari 10 ibu yang memasuki usia menopause, 7 orang diantaranya mengatkaan tidak tahu tentang perubahan pada masa menopause. Pengetahuan ibu terhadap perubahan pada masa menopause masih di anggap kurang. Sedangkan 3 dari 10 orang ibu menopause yang kurang pengetahuannya dapat di lihat dari sikap terhadap prilaku hidup sehat dan dalam menanggulangi masalah yang kurang mengerti tentang sikap dalam menghadapi menopause. Tujuan penelitian ini adalah untuk mengetahui studi deskriptif tingkat pengetahuan ibu tentang perubahan psikologis pada masa menopause di Puskesmas Ampenan

Metode penelitian dalam penelitian ini adalah deskriptif. Populasinya adalah semua ibu menopause yang datang berkunjung ke Puskesmas Ampenan  sebanyak 1.425 Orang. Teknik pengambilan sampel dalam penelitian ini adalah accidental sampling sehingga jumlah sampel yang diperoleh sebanyak 30 orang. Alat bantu yang digunakan adalah kuesioner. Analisa yang digunakan adalah analisa univariat.

Hasil penelitian menunjukkan bahwa dari 30 ibu menopause yang diteliti, sebagian besar berada pada kelompok umur >55 tahun sebanyak 18 orang (60%), pendidikan menengah sebanyak 16  orang (53,3%) dan tidak bekerja sebanyak 19 orang (63,3%) dengan pengetahuan yang cukup tentang perubahan psikologis pada masa menopause sebanyak 14 orang (46,7%).
Ahlakî Yükümlülük ve Ahlakî Nesnellik
Authors: Beki Münteha
Published: September 2022

“Neden ahlaklı olmalıyım?” sorusu ahlaka ilişkin değer yargılarımızı ve motivasyonlarımızı belirleyen en temel sorudur. Bu soruya bağlı olarak ahlaklı olmanın neden bir gereklilik olduğu ve ahlaki yükümlülüklerin kaynağının ne olabileceği önemli bir sorunsaldır. Ahlaki doğrular insanların bu doğrulara uygun davranışlarda bulunmalarını zorunlu hissettikleri ve bu nedenle bu doğrulara aykırı davranmaktan kaçınmaya çalıştıkları birtakım yasalardır. Bir yasanın ya da doğrunun zorunlu kabul edilmesi halinde buna uymamak insan için yanlış olacağı için bunun doğru olması kendi başına bir yaptırım gücü oluşturacaktır. Ahlaki yükümlülüklerin kaynağını ahlaki doğruların nesnel olması, dolayısıyla zorunlu doğrular olmasından aldığı söylenebilir. Bu ise ahlaki doğruların ve yükümlülüklerin kaynağının insanı aşan bir düzleme referansı olduğu anlamına gelir. Bu çalışmada ahlaki yükümlülüklerin mümkün olup olmadığı, mümkünse bunların mahiyeti ve kaynağının ne olabileceği soruları üzerinde durulacaktır. Bu sorular realist bir ahlak anlayışı çerçevesinde ele alınarak Tanrı ve ahlak arasında bir ilişkinin kurulabileceği ve buna bağlı olarak ahlaki yükümlülüklerin Tanrı’ya dayandırılması gerektiği iddia edilecektir.
Tepotinib (Tepmetko)
Authors: CADTH
Published: September 2022

CADTH recommends that Tepmetko not be reimbursed by public drug plans for the treatment of locally advanced unresectable or metastatic non–small cell lung cancer (NSCLC) harbouring MET tyrosine kinase receptor exon 14 (METex14) skipping alterations.

The clinical evidence reviewed by CADTH was not strong enough to show whether treatment with Tepmetko benefits patients with locally advanced or metastatic NSCLC harbouring METex14 skipping alterations. It is not known if Tepmetko would lead to better outcomes for patients compared to treatments that are currently available.

Patients identified a need for treatments that stop or slow the progression of disease, prolong life, promote independence, improve symptoms and quality of life (QoL), and have minimal side effects. It is not clear whether Tepmetko meets these needs.
Letter to the Editor Regarding CADTH rapid review: Systemic Thrombolysis by Alteplase for Acute Ischemic Stroke
Authors: Micieli Andrew , Krawczyk Michal , Hunter Gary , Blacquiere Dylan , Demchuk Andrew M.
Published: September 2022

The Canadian Stroke Consortium read with interest the recent rapid review by CADTH on the evidence of alteplase for acute ischemic stroke. We felt it necessary to reply for several reasons:

despite the 27-year history of alteplase since the NINDS publication, the rapid review limits the search to the last 6 years, which does not reflect the totality of the evidence,
the process for inclusion of studies was questionable, leading to a strongly biased representation of the existing literature, and
important concerns from the single expert reviewer were not adequately addressed prior to publication.
Graphene layers for corrosion protection of steel
Authors:   , James Liam A.
Published: September 2022

Graphene coatings have previously been used on various metals to prevent corrosion. The corrosion of steels in modern environments is a costly and ongoing issue that may be aided by graphene coatings. This project focused on forming graphene coatings formed on steel samples in a quartz-tube furnace. The coatings were analysed for their quality, and corrosion testing was performed on the coated steel. The graphene coatings were found to have superior corrosion resistance compared to uncoated samples.
Synthesis and Characterization of CNT/PVA Nanocomposites for Electrical, Thermal and Morphological Properties
Authors: Nasar Gulfam , Khalil Uzma , Khan Muhammad Saleem , Nadeem Qaisar
Published: September 2022

The goal of the current work is to bring a helpful substance to nanoscience and nanotechnology that might be a "problem solver" for ion storage. Carbon nanotubes/ PVA nanocomposites were prepared in five concentrations in aqueous medium following film formation. The resulting nanocomposites were characterized using “AC Impedance Spectroscopy, Differential Thermal Analysis, Thermal Gravimetric Analysis / (TG/DTA) and Scanning Electron Microscopy (SEM)”. Ionic conductivity of the nanocomposites was determined from impedance spectroscopy. CNT/PVA nanocomposites exhibited lower conductivity as compared with CNT or PVA separately. TG/DTA graphs exhibited a regular pattern, showing an increase in the thermal stability. Morphology of the prepared samples as shown by SEM reveals a favourable polymer-filler morphological arrangement at the interphase, which is suggestive of a favourable compatibility between the polymer and the filler substance.
Role of Nacre and Biodentine to Inducing the TGF-β1 in the Dentin Tertiary Formation on the Pulpitis Reversible of Rattus norvegicus
Authors: Agustina Marpaung Yeamy , Abidin Trimurni , Ilyas Syafruddin , Nainggolan Irwana , A. Gani Basri
Published: September 2022

Pulpitis can cause sensitivity and trigger endodontic infections that threaten to lose dentin. Nacre and Biodentine were reported as a stimulator of TGF-β1 expression to induce tertiary dentin formation. To evaluate the ability of Nacre and Biodentine in inducing the TGF-β1 expression of tertiary dentin formation. Thirty male Wistar rats (Rattus Novregicus) were divided into three groups. Haemotoxylin and Eosin staining observed the dentinal bridge formation while TGF-β1 expression was evaluated by immunohistochemistry. Quantitative data were obtained based on the staining score. Kruskal-Wallis tests were used for statistical analysis. Nacre contains Calcium (95.04%), Oxygen (4.96%), and Carbon (0%). The dentin bridge formed after induced by Nacre and Biodentine was significant (p<0.05). Biodentine is stronger in reducing dentin bridges than Nacre in the hard tissue formed of the initial dentinal bridge and complete dentin bridges. The Quantity level expression of TGF-β1 of dentine is higher than that influenced by Biodentine compared to the Nacre of all score categories. They are significant among the treatment of 7 days, 14 days, and 30 days (p<0.05). Nacre and Biodentine can support the healing of reversible pulpitis of Rattus novregicus, which is indicated by an increase in TGF-β1 expression in inducing the dentinal bridge formation of 7, 14, and 30 days.
Chemical Constituents of Moringa oleifera Leaves of Ethanol Extract and its Cytotoxicity against Enterococcus faecalis of Root Canal Isolate
Authors: Soraya Cut , M. Alibasyah Zulfan , Nazar Muhammad , A. Gani Basri
Published: September 2022

Moringa oleifera has been famous as a natural medicine due to its rich vitamins, minerals, and flavonoids. However, the study of its effect on Enterococcus faecalis (E. faecalis) is limited. This study analyzes the chemical constituents of the ethanol extract of Moringa leaves using GC-MS and assessing the toxicity against E. faecalis. Moringa oleifera leaves were extracted by ethanol, evaporated, and the concentrated extract was analyzed using GC-MS instruments. The effect of cytotoxic of Moringa oleifera against E. faecalis was investigated by morphological and coagulation cells; also, the toxicity area was evaluated by ImageJ software. The GC-MS Spectrum was confirmed by NIST databased resulted in 17 different compounds including Alpha-butyrolactone, 1,3-cyclopentanedione, Glycerin, Cis-1,2,6-trimethylpiperidine, 1,2-epoxy cyclohexane, benzeneacetaldehyde, Isobutyraldehyde, propylhydrazone, 2-pyrrolidinone, 2-butenamide,2-cyano-3-hydroxy, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, 2-trideuteromethoxy-3-methyl pyrazine, Benzeneacetonitrile,4-hydroxy-, 1,2,3,3a,4,8b-hexahydrocyclopenta[b]indole, 1,3,4,5-tetrahydroxy-cyclohexane carboxylic acid, Hexadecanoic acid, n-cbz-beta-alanine, and 3-(2,2-dimethyltetrahydrofuran-3-yl)phenol. These active compounds are involved in the cytotoxicity against E. faecalis. The Moringa oleifera leaves have better toxicity at lower concentrations (12.5% and 6.25%) with 24 hours of incubating.: At least 17 chemical components were detected in the ethanol extract of Moringa oleifera leaves with quinic acid, glycerol, and DDMP as the most abundant compound. They probably affect the toxicity of E. faecalis cells.
Fourier Transform Infrared Spectrophotometry: An Eco-friendly green tool for quantification of Omeprazole in Pharmaceutical formulation
Authors: Prajapati Parixit , Chandarana Chandni
Published: September 2022

An eco-friendly method for quantification of Omeprazole in Pharmaceutical solid dosage form has been developed using Fourier transform infrared spectrophotometry. The proposed method avoids use of solvents which are commonly used for other methods of quantification e.g. Liquid Chromatography, UV spectrophotometry etc. The developed method has been validated for quantification of Omeprazole in marketed formulation as per ICH Q2 R (1) guidelines. The method is based on Beer-lamberts’ law. For the quantification C-O stretch absorption band at 1204 cm−1 was selected which is typically in the range of 1300 – 1000cm-1 in IR spectrum. The linearity of Omeprazole was obtained in the concentration range of 5 – 30mg/g with R2 value of 0.999. The % recovery was calculated with Intra and Inter day precision study.
The utilization of plant extracts/biomaterials for the green synthesis of nanoparticles, their biological activity and mode of action
Authors: Ali Esmail Al-Snafi  , Hussein Ali Hussein Al-Sa'idy  , Hussein Kamil Hamid
Published: September 2022

Nanotechnology is one of the modern approaches that has found access to the medicinal as well as pharmaceutical uses where the nanoparticles of the nobel as well as other metals nanoparticles and their oxides have been reported to exploite various biological activities particularly antimicrobial besides antineoplastic activities. In addition, metal/metal oxides nanoparticles have also been proposed to have diagnostic applications in radioscanning of neoplastic diseases besides pharmaceutical application in neoplastic drugs delivery. Green/eco-friendly synthesis of these nanoparticles using biomaterials is considered as an innovatory approach for their production through which attaining economically beneficial along with drastic polluting methods avoidance advantages. In this context, plants extracts are increasingly finding the way for their production. In this survey, the green chemical synthesis approaches of nanoparticals of different metals and their oxides, their medical uses and biological activities, particularly antimicrobial mechanism of silver nanoparticles, as well as antineoplastic activity are discussed. The outcomes of this survey encourage us to conclude the feasibility of investment in the investigations in this approach.
Effect of aqueous and ethanol leaves extracts of Justicia carnea on selected biochemical and haematological parameters in Albino Mice
Authors: Peters DE  , Ahaotu O  , Wegwu MO
Published: September 2022

This study investigated the effect of aqueous and ethanol leaves extracts of Justicia carnea on selected biochemical and haematological parameters in albino mice. LD50 for the ethanol extract was carried out using the guidelines proposed by organization for Economic Cooperation and Development (OECD). Twenty four mice were divided into six groups of four mice/group. Groups 1 and 2 received distil water and 3%DMSO respectively as normal control, groups 3 and 4, 5 and 6 received 500 and 1000mg/kgbw of aqueous and ethanol leaves extracts respectively for six days. Mice were sacrificed 24 hours after the sixth day of treatment and blood sample collected for biochemical and haematological investigations. Result of quantitative phytochemical constituent of the leaves revealed the presence of alkaloids (1.01x10-1), terpenoids (8.55 x 10-1), saponin (449.43), sterols (30.58), phenolic acids (38.73), glycosides (39.27), flavonoids (430.24), tannin (744.24) mg/100g, oxalate (102.11) and phytate (12.37) ppm. Aqueous leaves extract showed significant (p≤0.05) increase in PCV, Hb and platelet values, while others were non-significant while ethanol extract was non-significant (p≥0.05) in all haematological parameters when compared to control. Significant decrease (p≤0.05) was observed in AST, ALT activities and Total bilirubin concentration in all the groups for aqueous extract and non-significant differences (p≥0.05) in all liver markers for all ethanol extract treated groups when compared to control. Aqueous and ethanol extracts of Justicia carnea did not have any toxic effect on the experimental animals however aqueous extract boosted haemoglobin level.
建置全院性「智慧化、行動化臨床早期預警系統(Early Warning System, EWS)」
Authors: 陳厚全 陳厚全 , Hou-Chaung Chen 徐永年
Published: September 2022

在醫療機構導入早期預警系統(Early Warning System, EWS)是全世界醫療照護的趨勢之一。本院獲得英國皇家醫師學會(Royal College of Physicians, RCP)授權，導入其發展的臨床早期預警系統(National Early Warning System, ver. 2, NEWS2)，並於2020年7月在醫院全面建置。

本院自行開發的智慧化、行動化EWS除包含NEWS2外，亦納入ISBAR、qSOFA、互動式團隊溝通及社交媒體(LINE)實名登錄EWS的資安機制。除此之外，也調整醫療照護模式，建立EWS監控中心、臨床督導團隊(Medical Audit Team, MAT)及緊急應變團隊(Rapid Response Team, RRT)，能夠及早介入病情惡化病人的臨床治療，避免演變成醫療意外事故。

導入EWS後的成果：1.非預期急救事件發生率降低31%、急救後死亡率降低50%；2.可即時掌握病人生理資訊，促進醫護溝通。

 

Implementation of early warning systems (EWSs) in medical institutions has become a healthcare trend worldwide. The case hospital received authorization from the Royal College of Physicians to implement its National Early Warning System ver. 2 (NEWS2). The hospital-wide implementation of the system was completed in July 2020.

The hospital developed its own smart and mobile EWS system, in addition to NEWS2, and also adopted the ISBAR (identification, situation, background, assessment, recommendations) tool, the qSOFA (quick Sequential Organ Failure Assessment), interactive team communication, and used the LINE real-name registration mechanism to protect patient data. Also modified the hospital’s healthcare workflow to establish an EWS monitoring center, medical audit team, and rapid response teams, helping patients with deteriorated conditions to receive timely clinical retreatment to prevent medical accidents.

After the EWSs were implemented, the incidence rate of unexpected CPR decreased by 31%, the mortality rate after CPR decreased by 50% as well as helped healthcare providers were well-timed to obtain patients’ physical information, and facilitate interprofessional communication.

 
重拾年輕的關鍵—台灣基督長老教會馬偕醫療財團法人淡水馬偕紀念醫院參與「關節置換照護品質認證」經驗分享
Authors: 盧永昌 盧永昌
Published: September 2022

關節置換團隊為本院骨科部秉持著「科有特色、人有專長」的專科化發展模式而成立，為積極提升「全人工關節置換疾病」照護品質，病人術前進行醫病共享決策，並納入手術部位感染組合式照護，進行監測、管理，並於出院後提供督導式復健療程。為持續精進，本院將導入術後加速康復(ERAS)，包含術前體能優化、術中多模式止痛、噁心嘔吐預防，透過團隊合作加速康復。病人的高滿意度，實為我們團隊帶來持續精進之動力，亦為品質認證的價值所在。

 

The Department of Orthopedics of MacKay Memorial Hospital Tamsui Branch established a joint replacement team based on the principles of specialized development model for "departmental features and specialist development" to actively improve the quality of care for patients with total knee replacement. Before the surgery, through shared decision - making between the physician and the patient and the incorporation of care bundles for surgical site infection, the patient’s conditions are monitored and managed. After the patient is discharged, supervisory rehabilitation treatment processes are provided to the patient. To enable continuous improvement, the hospital will introduce enhanced recovery after surgery, which includes presurgical physical optimization, multimodal pain relieving and prevention of nausea and vomit during the surgery, and teamwork-based enhancement of recovery. Patients’ high satisfaction levels motivate the continuous improvement of the team and mark the value of care certification.

 
大規模疫苗施打時的安全監測與疫苗不良事件
Authors: 邱南昌 邱南昌
Published: September 2022

在全球性大流行的情況下，疫苗的大規模施打對疫情的控制有很大的幫助，然而疫苗施打也會引發不少疑慮。施打疫苗後發生的不良事件是指施打後發生影響健康的事件，與疫苗間並不必然具有因果相關性，但若媒體進行錯誤報導，謠言可能會對民眾施打疫苗的意願影響甚大；而疫苗不良反應指的是疫苗的副作用，分為注射部位的局部反應、全身性反應及過敏反應。臺灣有被動監測的疫苗不良事件通報系統、主動監測的V-Watch預防接種健康回報，用以監測大規模施打疫苗後是否有安全警訊出現，亦有預防接種受害救濟制度可給予真的受害者適當救濟。對於疫苗安全性的信任是提高接種率、快速控制疫情的重要因素，在良好的監測下，民眾應可放心接種。

 

Although mass immunization assists in pandemic control, many people have doubts about receiving vaccines. Adverse events that occur after vaccination are generally related to other health problems rather than the vaccines themselves. However, inaccurate media reporting on such events may considerably influence people’s willingness to receive vaccinations and may causing vaccine hesitancy. Adverse vaccine reactions are side effects of vaccines, including local reactions at the injection site, systemic reactions, and allergic reactions. Taiwan established a passively monitored Vaccination Adverse Event Reporting System and an actively monitored Taiwan V-Watch System to monitor the adverse events of the COVID-19 vaccines to identify potential safety concerns. Taiwan also established the Vaccine Injury Compensation Program, which offers financial relief to those who experience adverse reactions. Establishing trust in the safety of vaccines is crucial to ensure the vaccination rates and outbreaks control. People should feel confident in receiving vaccines, since the effects of such vaccines are under well monitoring.

 
醫療場域中的性別圖像
Authors: 邱鈴真 邱鈴真
Published: September 2022

性別平等是一個廣泛的議題，透過性別圖像之「權力、決策與影響力」、「就業、經濟與福利」、「教育、媒體與文化」、「人身安全與司法」、「健康、醫療與照顧」及「環境、能源與科技」等六大領域可以試圖瞭解醫療場域中性別議題的樣貌與發展：醫療機構如同其他機構一樣大多是以男性為主導；醫事人員受到性別職業刻版印象及性別角色限制，使其職涯發展受到限制；性平意識教育在學校基礎教育、醫事人員培育、繼續教育等階段雖有相關規範，仍建議檢討執行成效；醫療場域管理者應就職場互動及醫病關係兩面向採行性別相關政策；醫療人員提供醫療照護時，應看見病人生理性別與社會性別交織的影響；醫療院所可建立各族群性別友善措施評核指標，營造性別友善醫療環境。性別議題在醫療場域中需要各面向的努力，也是政策推動與醫院管理者應重視的課題。

 

Gender equality is a wide topic. Through the six major aspects of "Power, Decision-making, and Influence," "Employment, Economy, and Welfare," "Education, Media, and Culture," "Personal Safety and Justice," "Health, Medical Service, and Care," and "Environment, Energy, and Technology," we may understand the morphology and development of gender issues in the healthcare field. Healthcare facilities, like other facilities, are mainly dominated by men. Medical personnel are subject to gender-specific stereotype of occupation and gender role limitation, which restrict the personnel’s career development. Although regulations regarding gender equality awareness and education are provided in basic school education, training of medical personnel, and advanced education, the implementation effectiveness requires evaluation. Managers in healthcare fields shall adopt gender-related policies in terms of workplace interaction and physician–patient relationships. When health professionals provide health care, they shall identify the effect of the interaction between the patients’ physiological sex and social gender. Healthcare institutions are recommended to establish gender-friendly measures and relevant evaluation indicators to create gender-friendly healthcare environments. Gender issues in the healthcare field require efforts from all aspects and attention from the policy implementation agents and hospital managers.

 
A Literature Review of Patient-related Risk Factors for Late Implant Failure
Authors: Shih-Hsuan Tsai Shih-Hsuan Tsai , Shih-Hsuan Tsai Yu-Lin Lai , Yu-Lin Lai Yi-Chun Lin , Yi-Chun Lin Hsuan-Hung Chen , Hsuan-Hung Chen Shan-Ling Hung , Shan-Ling Hung Ching-Yi Wu , Ching-Yi Wu Chien-hsin Wang , Chien-hsin Wang Ya-Chi Chen
Published: September 2022

Abstract: Short-term outcome of dental implants is predictable, but variable long-term results are noticed. Cluster effect of implant failure had been reported in previous studies and many patient-related risk factors have been claimed to be associated with implant failure. This review was investigated the correlation between patient-related factors and late implant failure, and further provide a preview of potential risk indicators in late implant failure for clinicians. Regarding to current evidences, history of periodontitis does have negative effects on implant survival, but comparable results can still be obtained after intensive periodontal treatment and maintenance. The direct cause-and-effect of smoking habit and late implant failure can still not be determined. Well-controlled Diabetes mellitus (DM) patients present comparable long-term outcomes. Moreover, some moderate-controlled DM (HbA1c = 7.2 – 10.0%) patients can still benefit from implant therapy under limited risk. Most of the studies suggest that implants in bruxers may have higher chance of mechanical complication. The negative effects of radiotherapy (RT) are related to its dose, interval between implantation and damage of salivary gland. Incorporating oral rehabilitation plan before RT may provide better outcomes. Lastly, poor compliance to supportive implant treatment (SIT) is significantly related to peri-implant bone loss, increasing probing depths and eventually implant failure. Before implant therapy, we should pay more attention about patient’s condition and further make comprehensive treatment plan for long-term success. Check DM patient’s blood sugar and consult physical doctor before surgery. Incorporate oral rehabilitation plan before RT to cancer patient and communicate with cancer physician. Suggest patient quit smoking and consult specialist for management bruxism condition. Lastly, keeping SIT program is important in implant patients, especially with history of periodontitis.

 
Rezension von: Müller, Matthias; Winter, Sascha (Hrsg.), Die Stadt im Schatten des Hofes?
Authors: Ohm Matthias , Müller Matthias , Winter Sascha
Published: September 2022

Matthias Müller / Sascha Winter (Hg.), Die Stadt im Schatten des Hofes? Bürgerlich-kommunale Repräsentation in Residenzstädten des Spätmittelalters und der Frühen Neuzeit. 2. Symposium des Projekts „Residenzstädte im Alten Reich (1300 – 1800)“ der Akademie der Wissenschaften zu Göttingen in Mainz, 14. – 16. September 2017 (Residenzenforschung, NF: Stadt und Hof 6). Ostfildern: Jan Thorbecke 2020. 335 S., 82 S. Bildtafeln. ISBN 978-3-7995-4538-9. Geb. € 64,–
Rezension von: Militärhistorisches Museum Dresden (Hrsg.), Krieg Macht Nation
Authors: Steinbach Peter , Militärhistorisches Museum
Published: September 2022

Militärhistorisches Museum Dresden (Hg.), KRIEG MACHT NATION. Wie das deutsche Kaiserreich entstand. Dresden: Sandstein Verlag 2020. 432 S. mit 474 Abb. ISBN 978-3-95498-545-6. € 48,–
Rezension von: Becht, Hans-Peter, Handbuch der Badischen Ständeversammlung und des Badischen Landtags 1819–1933
Authors: Fehrlen-Weiss Nina , Becht Hans-Peter
Published: September 2022

Hans-Peter Becht, Handbuch der Badischen Ständeversammlung und des Badischen Landtags 1819 – 1933 (Veröffentlichungen der Kommission für geschichtliche Landeskunde in Baden-Württemberg), 2 Bde. Stuttgart: Kohlhammer 2021. 1066 S. ISBN 978-3-17-039999-0. Geb. € 88,–
Rezension von: Dornheim, Andreas, Beamte, Adjutanten, Funktionäre
Authors: Bacher Frederick , Dornheim Andreas
Published: September 2022

Andreas Dornheim, Beamte, Adjutanten, Funktionäre. Personenlexikon zum Reichsministerium für Ernährung und Landwirtschaft und Reichsnährstand. Stuttgart: Kohlhammer 2021. 339 S. ISBN 978-3-17-040086-3. Kart. € 59,–
Rezension von: Kühne, Hartmut; Roth, Gunhild (Hrsg.), Andacht oder Abenteuer
Authors: Reichert Folker , Kühne Hartmut
Published: September 2022

Hartmut Kühne / Gunhild Roth (Hg.), Andacht oder Abenteuer. Von der Wilsnackfahrt im Spätmittelalter zu Reiselust und Reisefrust in der Frühen Neuzeit (Jakobus-Studien, Bd. 23). Tübingen: Narr Francke Attempto Verlag 2020. 376 S. zahlr., z. T. farb. Abb. ISBN 978-3-8233-8388-8. € 58,–
Rezension von: Kremer, Joachim; Haag, Norbert; Holtz, Sabine (Hrsg.), Die Kantate im deutschen Südwesten
Authors: Poetzsch Ute , Kremer Joachim , Haag Norbert , Holtz Sabine
Published: September 2022

Joachim Kremer / Norbert Haag / Sabine Holtz (Hg.), Die Kantate im deutschen Südwesten. Quellen, Repertoire und Überlieferung 1700 – 1770 (Stuttgarter Musikwissenschaftliche Schriften, Bd. 6). Mainz: Schott Music 2021. 296 S. ISBN 978-3795719258. € 32,–
An unusual case with a challenging combination of glaucoma, keratoconus, and ocular surface disease
Authors: Sreekanth Gayathri , Jones Nicky
Published: September 2022

A 64-year-old gentleman presented for the first time with severe pain, redness, and blurred vision in his left eye with examination revealing corneal hydrops. Discussion with the patient revealed a complex history of bilateral keratoconus and glaucoma. He also had chronic kidney disease, diabetes, Parkinson’s, and mental health conditions. Management of the patient involved a delicate balance between building enough trust to allow examination of the anxious patient without pushing too hard that he would not come back for treatment. Treatment was further complicated when he developed Herpes Simplex Keratitis and a rise in his intraocular pressures. The patient was not comfortable being in a hospital environment as he felt that he would “catch something,” he would also refuse some examinations and tests. However, with a gentle approach and support from occupational therapy and community nursing teams, a way forward was found that enabled him to remain living independently.
Determination of physical and mechanical properties of plywood produced using beech, okoume and ozigo species
Authors: BİRİNCİ Emre
Published: September 2022

Wood and wood-based materials are widely used in the construction industry in the world. The sustainable and renewable nature of wood is seen as an important advantage in contrast to non-renewable resources such as aluminum, steel, concrete, and plastic. In order to protect the advantages of wood and eliminate / reduce its disadvantages, plywood, particle board, fiber board, LVL, CLT, wood plastic composites etc. such as new wood-based engineering products are produced. Plywoods are widely used in automotive, construction, furniture, and many industries. In our country, plywoods are produced using tropical species as well as native tree species. In this study, density, water absorption, thickness swelling, bending resistance, elasticity of modulus in bending and shear strength values of plywood made of beech, okoume and ozigo wood species are investigated. Comparison of plywood produced from tropical species with beech has been made. It has been determined that beech plywood has higher density than okoume and ozigo plywood. It has been determined that beech plywood has higher density than okoume and ozigo plywood. It has been observed that there is a linear relationship between the bending strength, elasticity modulus and shear strength values of beech plywood and their full dry density.
La importancia de la invarianza métrica para la investigación en sociología
Authors: Miranda Daniel , Iturra Julio
Published: September 2022

Comparar variables latentes presenta importantes desafíos en cuanto a su equivalencia. Usando los datos del estudio ICCS 2016, en la que participaron 24 países, evaluamos la adecuación métrica de concepto de actitudes hacia la igualdad de derechos contrastando un modelo unidimensional (disponible en la documentación original) con un modelo bidimensional. Además, evaluamos los niveles de comparabilidad de las mediciones con análisis factorial confirmatorio multigrupo. Los resultados muestran que el modelo bidimensional logra sustanciales mejoras. Adicionalmente, la evaluación de la invarianza del modelo bidimensional muestra adecuados niveles de comparabilidad (invarianza métrica y escalar). Esto quiere decir que el instrumento especificado en sus dos dimensiones posee una comprensión similar por los participantes de los distintos países de la muestra. Por tanto, se podría comparar los niveles de cada dimensión y la relación de estas dimensiones con otras variables.