bluuebunny/crossref_metadata_2025 huggingface dataset:
EDUCAÇÃO DO CAMPO NOS ANAIS DO CONGRESSO BRASILEIRO DE ETNOMATEMÁTICA
Authors: Silva Márcia Regina de Souza , Leite Kécio Gonçalves
Published: August 2023

O presente artigo apresenta os resultados de um estudo de caráter bibliográfico com o objetivo de analisar, a partir dos anais das cinco primeiras edições do Congresso Brasileiro de Etnomatemática (CBEm), como as publicações neste evento, na modalidade comunicações orais, têm definido e referenciado teoricamente a educação do campo, com um recorte ainda mais específico das que se referem a pesquisas no espaço escolar. Inicialmente, para a seleção dos trabalhos, utilizamos os descritores educação do campo, rural e agricultura. Em seguida, mantivemos no corpus de análise apenas os trabalhos relacionados a pesquisas cujos dados foram produzidos em espaços escolares. Como resultados, foram identificadas 9 (nove) comunicações orais, a partir das quais foi possível verificar que, embora a etnomatemática esteja definida e referenciada teoricamente nos trabalhos apresentados no CBEm, isto não ocorreu com a educação do campo. Em 7 (sete) dos trabalhos analisados, verificou-se uma lacuna ou uma ausência de definição do que os pesquisadores entendem por educação do campo, e até mesmo a inexistência de referenciais teóricos que discutem a educação do campo. A partir de tais resultados, é possível fazer o indicativo à comunidade de pesquisadores que estudam a interface da etnomatemática com a educação do campo, no sentido da necessidade de uma maior aproximação teórica de suas pesquisas com o movimento que culminou com as Diretrizes Gerais para a Educação Básica nas Escolas do Campo, fruto das experiências desenvolvidas no contexto de luta dos movimentos sociais camponeses por terra e educação.Palavras-chave: Etnomatemática; Educação do Campo; Espaço Escolar.
ANÁLISE DA IMPORTÂNCIA E UTILIZAÇÃO DO TÊNIS DE MESA NA EDUCAÇÃO FÍSICA ESCOLAR
Authors: Araújo Moisés de Lima , Mourão Nádia Dutra de Morais , Freitas Nairana Cristina Santos , OLIVEIRA Luis Carlos Goncalves de , Magalhães Neto, Aníbal Monteiro de , Socorro Patrícia Chaves de Araújo do
Published: August 2023

O estudo tem o propósito de investigar qual é a importância e utilização do tênis de mesa na educação física escolar e, como são desenvolvidas as aulas através desse jogo. Esse conteúdo dentro do ambiente escolar proporciona um grande diferencial, bem como, trabalha diversas habilidades que as crianças e jovens necessitam para o crescimento físico e intelectual. Dessa forma, é importante ressaltar que essa prática deve ser constituída de maneira pedagógica e gradativa. Com essa dinâmica simples, o tênis de mesa abre possibilidades para o desenvolvimento de muitas habilidades. De maneira geral, é importante identificar se as escolas estão equipadas com material adequado para as práticas desta modalidade. Assim, nosso objetivo é identificar a existência desses materiais nas escolas, como estão sendo manuseados e reproduzidos nas aulas de educação física. Ao realizar esse esporte o aluno consegue ter tomadas de decisões que influenciam tanto no jogo, como na vida. A integração com outros participantes propicia a interação e socialização entre os diferentes tipos de pessoas. O estudo foi estruturado em uma pesquisa de campo nas escolas privadas, municipais, estaduais e federal da cidade de Barra do Garças- MT. Desse modo, foi aplicado um questionário, a fim de saber quais escolas utilizavam o tênis de mesa nas aulas de educação física.  É importante analisar nas instituições de ensino, pesquisadas, a existência de material disponível, porém, não é utilizado nas aulas de educação física. Dessa forma, deve-se recriar aparatos para que essa prática possa acontecer com mais frequência nas instituições de ensino. Palavras-chave: Tênis de Mesa; Educação Física; Escolas.
A BNCC E A EDUCAÇÃO DO CAMPO, DA INVISIBILIDADE A INSUBORDINAÇÃO CRIATIVA
Authors: SILVA Márcia Regina de Souza , PEREIRA Leiva Custódio , SILVA Helen Maciel da
Published: August 2023

Este artigo é resultado parcial de uma pesquisa em desenvolvimento no curso de Mestrado em Educação Matemática, do Programa de Pós-Graduação em Educação Matemática da Universidade Federal de Rondônia, de abordagem qualitativa, com procedimento bibliográfico e exploratório, analisa teses e dissertações constantes no banco de teses da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – CAPES, a partir do descritor Base Nacional Comum Curricular - BNCC, sendo identificados 49 trabalhos. Posteriormente, a partir da leitura dos resumos e palavras chaves, buscou-se localizar o descritor Educação do Campo, não constatando nenhuma ocorrência. Desta constatação buscou-se compreender o processo de elaboração, participação, interesses políticos e econômicos envolvidos na construção da BNCC, bem como a valorização às diversidades, a partir da seleção de 5 dissertações. Objetivando o aprofundamento do tema, analisou-se os Referenciais Curriculares do estado de Rondônia-RCRO e as Orientações Curriculares do município de Ji-Paraná/RO na busca das concepções de Educação do Campo. Como resultado, apontamos que para se efetivar uma política de Educação para o campo, é imprescindível a participação dos sujeitos afetos à política, formação inicial e continuada dos princípios de educação do campo e sempre quando necessário, a insubordinação criativa.Palavras-chave: Educação do Campo. Currículo. BNCC. Formação de Professores.
FERRAMENTAS DIGITAIS, CHAT E FÓRUM, EM TUTORIA ON-LINE EM EDUCAÇÃO A DISTÂNCIA
Authors: SALGADO Rodolfo
Published: August 2023

Este artigo objetiva discutir a interação dialógica em educação a distância, propondo-se responder às inquietações da ausência de intensa interlocução em tutoria on-line entre os tutores e estudantes dessa modalidade. Por isso, apresentamos, neste artigo, as ferramentas digitais Chat e Fórum como espaços virtuais sociais de interação dialógica e, também, como um momento de aprendizagem e construção de conhecimento que oportuniza o amadurecimento de posicionamentos enunciativos no encontro com o outro no contexto da coletividade. A fundamentação teórica e metodológica é com base em Bakhtin, em uma abordagem qualitativa na ótica da pesquisa-formação e a sua análise diz respeito às enunciações do tutor e estudantes no ambiente virtual de aprendizagem da plataforma Moodle. Concluimos que ainda existem abordagens pedagógicas concebidas por tutorias monológicas caracterizadas pela falta de intensa interlocução, aumentando a distância transacional entre tutor e estudantes em tutorias online.Palavras-chave: Dialogismo. Proposição Disparadora. Ferramentas Digitais. Tutoria On-line. Educação a Distância
REDEFINIÇÕES DAS AÇÕES DO PIBID NO CONTEXTO DA PANDEMIA DO COVID-19
Authors: TABORDA Cleuza Regina Balan , MELLO Ângela Rita Christofolo de
Published: August 2023

Este artigo tem por finalidade socializar as ações desenvolvidas junto ao Projeto de Pesquisa que se constitui em uma pesquisa de demanda espontânea denominado: “Ações do Programa Institucional de Bolsas de Iniciação à Docência nos anos iniciais da Educação Fundamental, em defesa do direito da alfabetização na perspectiva dos letramentos” aprovado pela Portaria nº 247/2000 e prorrogado pela Portaria nº851/2021. A pesquisa objetiva analisar os problemas de aprendizagem dos estudantes matriculados no ciclo da alfabetização e II ciclo do ensino fundamental das escolas parceiras dos subprojetos vinculados ao Programa de Bolsas de Iniciação à Docência (PIBID/2020/202). Objetiva ainda, oportunizar aos Bolsistas de Iniciação à Docência (ID) dos subprojetos de Iniciação à docência nos anos iniciais do Ensino Fundamental, aprovado no Edital Pibid n° 01/2020/CAPES, para o curso de pedagogia ofertado na Universidade do Estado de Mato Grosso (UNEMAT), campus de Juara, aprofundamento teórico, conceitual, metodológico e vivências práticas por meio da aproximação das especificidades requeridas pelo processo de alfabetização na perspectiva dos letramentos. Adotou-se uma abordagem qualitativa com enfoque na pesquisa-ação/intervenção. Contudo, diante da pandemia que assolou o mundo em decorrência do Covid-19 as ações e estratégias do PIBID tiveram que ser redefinidas e readequadas diante das exigências e necessidades dos protocolos sanitários estabelecidos pelos sistemas em que as aulas presenciais foram substituídas por atividades não presenciais, por meio do ensino remoto emergencial. Esta nova modalidade possibilitou aos sujeitos envolvidos compreenderem os desafios e a multidimensionalidade que envolve a ação pedagógica na tentativa de garantir os direitos de aprendizagem dos educandos dos anos iniciais do Ensino Fundamental.
EFEITOS DA COVID-19 E DISTANCIAMENTO SOCIAL NA APRENDIZAGEM DA CRIANÇA NA EDUCAÇÃO INFANTIL: O DILEMA DO PARECER DO CNE
Authors: RAMOS Thays Aparecida
Published: August 2023

Este artigo tem como objetivo identificar os efeitos e impactos do distanciamento social na aprendizagem da criança da educação infantil, tomando como objeto de análise o posicionamento do Conselho Nacional de Educação (CNE) para a Educação Infantil em seu Parecer. Para tanto, confrontou-se esse Parecer com as Diretrizes Curriculares Nacionais para a Educação Infantil e a Base Nacional Comum Curricular (BNCC). Foram selecionadas normativas e orientações dos órgãos governamentais brasileiros para a educação no período de pandemia, consultados em sites oficiais do Governo e materiais que tratassem do assunto, disponibilizados na internet no período de março a setembro de 2020. Percebeu-se que o Parecer do CNE desconsiderou muitos aspectos referentes as especificidades do processo educacional na Educação Infantil, replicando mais as aspirações adultas, uma vez que se preocupou muito com a forma de distribuição das atividades e com os conteúdos a serem ofertados. Não houve estudo prévio para identificar as condições emocionais, econômicas, sociais e culturais das crianças atendidas. Esta lacuna poderá influenciar no aprendizado escolar na etapa seguinte, pois as drásticas mudanças na rotina e ambiente da primeira infância durante a pandemia, já apontam para alguns aspectos de impacto direto no desenvolvimento integral infantil.
CONSIDERAÇÕES À CRISE DO CAPITAL, PRECARIZAÇÃO DO TRABALHO E IMPACTOS NAS POLÍTICAS SOCIAIS
Authors: CORDEIRO Kassia Lorena Fernandes , CRUBELATI Ariele Mazoti
Published: August 2023

O presente trabalho pretende analisar e pontuar o contexto de reestruturação do capital mundializado, quais cenários favoreceram essa reestruturação e quais os impactos referentes à precarização do trabalho. Aborda questão como a informalidade para discutir a flexibilização no mundo do trabalho. Trouxemos como exemplo os reflexos nas políticas sociais, que originou as transformações societárias, os marcos históricos e particularidades da profissão Serviço Social. A análise bibliográfica reúne categorias de mediações essenciais para desvelar o sentido das determinações da alienação do trabalho no exercício profissional, enquanto profissão inserida na divisão social e técnica do trabalho coletivo no processo de (re)produção das relações sociais. Ainda elucida as manifestações da Questão Social presente nas contradições das políticas
OS CURRÍCULOS QUE FORMAM PROFESSORES DE MATEMÁTICA
Authors: GOMES Jennifer Boscato , BITENCOURT Loriége Pessoa
Published: August 2023

As discussões no âmbito da formação de professores vêm circunscrevendo um cenário de disputas externas e internas, com os orientativos da Resolução do CNE/CP nº 02 de 2019, e provocam mudanças nos currículos das licenciaturas. Com os debates atuais desenvolveu-se, junto ao Programa de Pós-Graduação em Educação (PPGEdu/UNEMAT), esta pesquisa de mestrado que aborda o currículo de uma Licenciatura em Matemática. Neste artigo, com base em três dissertações – Silva (2013), Santos (2018) e Souza (2020) – disponíveis no Catálogo de Teses e Dissertações da CAPES, selecionadas em um Balanço de Produção, elaborado por Gomes e Bitencourt (2021), visa-se saber: como os autores destas dissertações vêm discutindo os currículos que formam professores de Matemática? As principais características encontradas nessas dissertações dizem respeito às inconsistências nos Projetos Pedagógicos dos Cursos (PPC), no que se refere ao perfil do egresso e às concepções de currículo presentes nesses documentos. Conclui-se, neste artigo, que as produções científicas recentes corroboram as perspectivas já criticadas por pesquisadores ao longo dos anos.
JUVENTUDES CAMPONESAS: PERCEPÇÕES SOBRE CONFLITOS SOCIOAMBIENTAIS DA COMUNIDADE TRADICIONAL ZÉ ALVES E DO QUILOMBO LARANJAL NO MUNICÍPIO DE POCONÉ-MATO GROSSO
Authors: Bertoncello Jucieli , Jaber-Silva Michelle Tatiane , Silva Regina Aparecida da
Published: August 2023

Os conflitos socioambientais são decorrentes das disputas desiguais entre grupos sociais vulneráveis que têm sua cultura, identidade e território ameaçado por grupos dominantes, especialmente do agronegócio, que transformam os bens naturais em recursos para atender a lógica economicista, pautadas no produtivismo e consumismo. O objetivo desta pesquisa foi identificar as percepções das juventudes camponesas sobre os conflitos socioambientais existentes na comunidade tradicional Nossa Senhora de Lurdes (conhecida como Zé Alves) e na comunidade remanescente de Quilombo Laranjal, ambas localizadas no município de Poconé-Mato Grosso. A proposição investigativa apoiou-se no método qualitativo, tendo como táticas metodológicas o Mapa Social que buscou evidenciar os grupos invisibilizados e as injustiças socioambientais que transformam-se em conflitos à medida que a resistência e mobilização vão se instaurando nos territórios.
KAPSAYICI LİDERLİĞİN İŞE GÖMÜLMÜŞLÜK ÜZERİNE ETKİSİNDE LİDER ÜYE ETKİLEŞİMİNİN ARACI ROLÜ
Authors: ERKAL Pınar
Published: August 2023

Bu çalışmanın amacı kapsayıcı liderlik ve işe gömülmüşlük arasındaki ilişkiyi ve bu ilişkide lider üye etkileşiminin aracı rolünü incelemektir. Araştırma sonuçları 203 kamu çalışanından oluşturulan örneklem grubundan veri toplanarak elde edilmiştir. Elde edilen sonuçlara göre kapsayıcı liderliğin çalışanların işe gömülmüşlük düzeyini etkilediği tespit edilmiştir. Ayrıca lider üye etkileşiminin işe gömülmüşlük üzerinde etkisinin anlamlı olduğu belirlenmiştir. Kapsayıcı liderliğin işe gömülmüşlüğe etkisinde lider üye etkileşiminin aracı rolü tespit edilmiştir. Elde edilen sonuçlar doğrultusunda örgütlerde liderlerin kapsayıcı olması yani açık, ulaşılabilir olması ve çalışanlarla etkileşimlerinin bulunması çalışanların işe gömülmüşlüklerine katkı sağlayacaktır.
RELATIONSHIP BETWEEN WORK FRIENDSHIP AND INTENTION TO LEAVE: A LATENT PROFILE ANALYSIS
Authors: ANTALYALI Ömer Lütfi , EKŞİLİ Nisa , ÇETİNKAYA BOZKURT Özlem
Published: August 2023

The main purpose of this study is to reveal whether the intention to leave changes according to the characteristics of the relationships established with close friends in the workplace with a person-centered approach. For this purpose, latent profiles were established by ensuring that workplace friendship is affected by the intention to leave and job satisfaction. This article presents an example of a three-stage study using implicit profile analysis with 433 data obtained from private sector employees. The analysis uncovered four latent profiles. The Partially Autonomous Very Strong Bond profile has the highest job satisfaction and the lowest intention to leave. If the level of trustworthiness, competency, job satisfaction is higher and the intention to leave is lower. The Integrated Very Strong Bond profile is the profile with the highest intention to leave. In cases were caring personal relationships and socio-cultural similarity are high, lower job satisfaction and the higher intention to leave have been observed.
Popularizing the Gay Characters: A Study of American Gay-Themed TV Series in 2000s
Authors: Rudy Rudy , Wardana Muhammad Kiki
Published: August 2023

This study is a qualitative research which concentrates on the rise of TV series gay characters on American televisions starting in the early 2000s. The emergence of gay TV series in 2000s has made this phenomena interesting as well as essential to discuss since American television in the pre 2000s era was not not open about the gay characters in television series. The data for this study were obtained through a literature review consisting of journal articles as well as books. This study intended to identify why gay-themed TV series appeared in the 2000s by applying Hall’s theory of representation as a way for analyzing. This research is useful to an additional reference for other researchers and to increase people’s understanding on the gay TV series phenomenon in the US. The research findings showed that there at least four representations explaining the reasons for the emergence of gay-themed TV series in America – the progress of science and knowledge, the strength of minority, the state support, and the new target consumers.
Embracing Google Translate: EFL Students’ Attitudes on Enhancing Literacy Practice
Authors: Lia Delfitha , Tungka Novalita Fransisca
Published: August 2023

This study investigates students' attitudes toward the use of Google Translate (GT) in their online literacy practices. The study looks at the results of an online questionnaire survey completed by 70 students studying English Language Education at Universitas Sintuwu Maroso in Poso, Central Sulawesi. The purpose of this research is to examine how students' attitudes regarding GT manifest themselves in their reading practices, taking into account behavioral, cognitive, and affective components. The results showed that: First, from a behavioral standpoint, students consistently show a proclivity to actively use GT for various translation tasks, ranging from solitary words to complete paragraphs, essays, or articles; Second, students have differing cognitive attitudes about the ethical implications of GT use, with some viewing it as a sort of cheating depending on the context; Finally, on an affective level, students tend to accept the usage of GT as normal, enjoy using it, and may even become dependent on its features. This study gives insight on the complexities of students' attitudes toward GT and how these beliefs influence their literacy practices. Educators can better appreciate the obstacles and opportunities that come with the incorporation of GT in online language learning environments by understanding the behavioral, cognitive, and affective elements. This knowledge can be used to design successful educational practices that take advantage of GT's benefits while addressing its possible limitations in order to improve students' overall language ability.
Pengembangan Lembar Kerja Peserta Didik (LKPD) Berbasis Etnomatematika Budaya Minangkabau Pada Materi Kekongruenan dan Kesebangunan
Authors: Isnaniah Isnaniah , Firmanto Pipit , Imamuddin M.
Published: August 2023

This is motivated by the fact that there is no learning media based on Minangkabau culture in learning mathematics. This study aims to determine the validity, practicality and effectiveness of ethnomathematics-based Student Worksheets (LKPD) in Minangkabau culture on the material of congruence and congruence. The type of research used is Research & Development (R & D). The LKPD was developed based on the Plomp and Nieveen Model with 3 phases, namely: 1) preliminary research, 2) development or prototyping phase and 3) assessment phase. The formative valuations such as: self evaluation, expert review, one to one evaluation, small group and field tests, carried out in an integrated manner during the design phase. Data was collected through interviews, validation sheets, questionnaires and tests. The results showed: 1) Ethnomatematics-based LKPD validity obtained a percentage of 92% with a very valid category, 2) Practicality of LKPD in one to evaluation obtained a percentage of 90% with a very practical category, in the small group obtained a percentage of 95% with a very practical category. 3) The effectiveness of student worksheets seen from the results of students' mathematics learning, obtained student mastery of 86.7% with very effective criteria. The developed LKPD can be used in learning mathematics. Learning by involving Minangkabau culture can improve learning outcomes and develop and build student character. Based on the results of this study, educators are expected to develop teaching materials that are associated with local culture or the culture where students live. Once developed, then used in learning mathematics.
Analisis Kemampuan Representasi Matematis Siswa dalam Menyelesaikan Soal Berbasis HOTS Ditinjau dari Gaya Kognitif
Authors: Saputri Anggi Dodo , Faiziyah Nuqthy
Published: August 2023

Tujuan dari penelitian yaitu menganalisis kemampuan representasi matematis siswa dalam menyelesaikan soal berbasis HOTS ditinjau dari gaya kognitif Field Independent serta Field Dependent. Dengan menggunakan metode penelitian deskriptif kualitatif. Analisis data dengan mereduksi data, penyajikan data, dan pengambilan kesimpulan. Instrumen yang dipergunakan uji GEFT dan soal uji pemahaman ketrampilan representasi matematis berbasis HOTS. Siswa kelas VIII C dan D SMP sebagai subjek penelitian ini yang berjumlah 55 siswa. Hasil penelitian yang didapat yaitu: 1) Siswa yang termasuk dalam gaya kognitif field independent sudah bisa menyelesaikan soal dengan baik. Sehingga siswa mempunyai pemahaman konsep serta dapat merepresentasikan penyelesaian permasalahan secara benar. Sehingga siswa sudah bisa membentuk model matematis atau persamaan dari permasalah yang ada atau bisa didapatkan kesimpulan yaitu siswa yang termasuk kedalam gaya kognitif field independent mampu melibatkan representasi verbal, representasi simbolik serta representasi gambar dalam menyelesaikan permasalahan, 2) Siswa yang termasuk dalam gaya kognitif field dependent belum bisa dalam menyelesaikan soal yang sudah disajikan. Dalam merepresentasikan gambar, siswa belum mampu menyelesaikan masalah dengan melibatkan representasi gambar, hal tersebut bisa diamati dari hasil pengerjaan siswa. Materi SPLDV belum dikuasai dan dipahami siswa, dimana ini bisa ditunjukkan dengan kurangnya kemampuan siswa membuat persamaan atau model matematis, belum bisa menjawab pertanyaan dengan memakai teks tertulis atau kata-kata pada permasalahan. Maka dari hal tersebut, bisa didapatkan kesimpulan bahwa siswa yang memiliki gaya kognitif field dependent belum bisa melibatkan representasi verbal, representasi simbolik serta representasi gambar dalam menyelesaikan permasalahan.
Analisis Kesalahan Siswa Tipe Kepribadian Idealist dalam Menyelesaikan Masalah Statistika Berdasarkan Kriteria Watson
Authors: Hana Nibrisatul , Muksar Makbul , Slamet Slamet
Published: August 2023

Guru sering menemukan kesalahan siswa dalam proses pembelajaran, seperti kesalahan dalam memahami soal, perhitungan, dan menuliskan kesimpulan. Dengan mengetahui kesalahan setiap siswa, guru akan lebih mudah memperbaiki kesalahan siswa. Hal ini dilakukan dengan tujuan agar guru dapat membuat rencana untuk menindaklanjuti kesalahan siswa sehingga hasil pembelajaran dapat dicapai semaksimal mungkin. Memahami karakteristik siswa adalah salah satu komponen penting untuk meningkatkan hasil pembelajaran dalam mengembangkan potensi siswa secara optimal. Tipe kepribadian siswa adalah faktor yang dapat memengaruhi kegiatan belajar mereka. Karena tipe kepribadian siswa bervariasi dari satu siswa ke siswa lainnya, kemungkinan kesalahan yang dilakukan oleh siswa juga berbeda. Statistik adalah salah satu mata pelajaran sekolah menengah pertama di mana siswa sering melakukan kesalahan. Tujuan dari penelitian ini adalah untuk mendeskripsikan kesalahan yang dilakukan siswa tipe kepribadian idealist serta penyebab siswa melakukan kesalahan tersebut dalam menyelesaikan masalah statistika berdasarkan kriteria Watson. Penelitian ini merupakan penelitian deskriptif kualitatif yang dilakukan di SMP Ar Rohmah. Metode yang digunakan dalam penelitian ini meliputi angket, tes, wawancara dan dokumentasi. Hasil penelitian menunjukkan siswa tipe kepribadian idealist melakukan beberapa kesalahan seperti tidak menuliskan prosedur penyelesaian (ip), tidak menggunakan data yang tersedia untuk menyelesaikan masalah (od), langsung menuliskan kesimpulan tanpa disertai prosedur penyelesaian (rlc), kesalahan dalam perhitungan (shp) serta menuliskan kesimpulan namun tidak tepat (oc). Beberapa faktor yang menyebabkan kesalahan tersebut adalah siswa tidak paham dengan prosedur penyelesaian yang telah dilakukannya, tidak mengetahui prosedur penyelesaian masalah yang diberikan, dan kehabisan waktu dalam mengerjakan soal.
Proses Pemodelan Matematis Siswa dalam Memecahkan Masalah Program Linear
Authors: Amalia Zida , Sudirman Sudirman , Chandra Tjang Daniel
Published: August 2023

Beberapa penelitian menunjukkan bahwa siswa sekolah menengah di berbagai negara termasuk Indonesia, menghadapi kesulitan utama dalam memecahkan masalah soal cerita, terutama dalam topik aljabar ketika proses matematisasi. Proses ini salah satunya melibatkan pemodelan matematis. Berdasarkan permasalahan pemodelan matematis tersebut, perlu dikaji untuk mengetahui bagaimana proses membangun model matematika dengan langkah-langkah yang tepat agar dapat mencapai hasil yang optimal saat memecahkan masalah. Penelitian ini memiliki tujuan untuk menganalisis bagaimana proses siswa memodelkan matematika dalam memecahkan masalah program linear. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi kasus. Subjek penelitian adalah 3 siswa SMA dengan hasil jawaban berbeda ketika melakukan pemodelan matematis dalam memecahkan masalah program linear. Instrumen yang digunakan dalam penelitian ini meliputi lembar tes masalah program linear dan pedoman wawancara. Langkah pemodelan memecahkan masalah program linear pada penelitian ini yaitu mengidentifikasi variabel keputusan, mengonstruksi fungsi kendala dan fungsi tujuan, memverifikasi fungsi kendala dan fungsi tujuan yang telah dibuat. Hasil penelitian menunjukkan terdapat perbedaan melakukan seluruhnya atau belum seluruhnya langkah yang digunakan. Langkah mengidentifikasi variabel keputusan dilakukan oleh ketiga subjek, langkah mengonstruksi fungsi kendala dan fungsi tujuan dilakukan oleh dua subjek sedangkan langkah memverifikasi fungsi kendala dan fungsi tujuan hanya dilakukan oleh satu subjek.
The Human Papillomavirus and Its Relationship to Infertility and Endometriosis
Authors: Okyay Emre , Kula Hakan , Yavuz Onur , Akdoner Asli , Cagliyan Erkan
Published: August 2023

Background: The pathogenesis of endometriosis is still debatable, and many studies reported a predisposition to infectious and immunological factors. In this study, we aimed to evaluate the human papillomavirus (HPV) positivity in endometriosis pain-related symptoms and infertility. Methods: In this cross-sectional study, 410 endometriosis patients were enrolled in this study. HPV-positive (n = 202) and HPV-negative (n = 208) patients compared with pain-related symptoms, infertility, and endometrioma presence. The term “Other HPV” was utilized to encompass all HPV types with the exception of HPV 16 and 18, which were specifically identified as HPV 16/18. Results: Dyspareunia in the “Other HPV”-positive group (12.8 %) was statistically higher than in the HPV-negative group (4.8%; p = 0.007). The infertility rate was significantly higher in the HPV 16/18 positive group (high-risk HPV) 35.8% than in the HPV-negative (7.6%), and “Other HPV” positive group (8%; p < 0.001). Endometriosis-related pain symptoms were significantly higher in high-risk HPV (49%) than in the HPV-negative (37%), and “Other HPV” positive group (46.3%; p = 0.046). The ovarian endometrioma rate was slightly higher in group HPV 16/18 positive population (16.9%) than in “Other HPV” types positive (11.4%), and HPV-negative groups (7.2%; p = 0.08). Conclusions: Our results could provide a potential predisposing role of HPV infection in pain in endometriosis clinics and infertility. Moreover, HPV subtypes may have a different impact on clinical conditions.
A New XGBoost Algorithm Based Prediction Model for Fetal Growth Restriction in Patients with Preeclampsia
Authors: Li Haijuan , Wang Sumei , Zhan Chunyu
Published: August 2023

Background: To construct a predictive model for fetal growth restriction (FGR) in preeclampsia (PE) patients using extreme Gradient Boosting (XGBoost) algorithm. Methods: A prospective study was conducted in the Obstetrics Department of Wuming Hospital from October 1, 2016, to October 1, 2021. A total of 303 preeclampsia patients were divided into two groups based on FGR status (restricted vs. unrestricted group). The clinical data and laboratory indicators between the two groups were compared. Logistics multivariate analysis and the XGBoost algorithm model were used to identify the risk factors for FGR in preeclampsia. Moreover, we used the receiver operating characteristic (ROC) curve to verify the accuracy of the XGBoost algorithm model. Results: Multivariate analysis and XGBoost algorithm modeling could predict the risk factors for FGR using clinical data and laboratory indicators. ROC analysis revealed that the area under the curve of the XGBoost algorithm model was 0.851, indicating a good fit. Conclusions: The XGBoost algorithm model can predict the occurrence of FGR in preeclampsia patients. The top three risk factors, triglyceride (TG), total cholesterol (TC), and lipoprotein (a) [Lp (a)], can be used as important predictors of poor patient prognosis in clinical settings.
Unraveling the Mystery: Next Generation Sequencing Sheds Light on Neuroblastoma Pathogenesis and Targeted Therapies
Authors: Aktas Tekincan , Kızmazoglu Deniz , Aktas Safiye , Erol Aylin , Serinan Efe , Gokbayrak Ozde , Ozdemir Sefayi Merve , Altun Zekiye , Ozer Erdener , Cecen Emre , Ince Dilek , Olgun Nur
Published: August 2023

Background: There is considerable interest in the molecular evaluation of solid tumors in pediatric cases. Although clinical trials are in progress for targeted therapies against neuroblastoma (NB), novel therapeutic strategies are needed for high-risk cases that are resistant to therapy. The aim of the present study was to document the specific gene mutations related to targeted therapy in relapsed or refractory NB patients by using next generation sequencing (NGS). Methods: The study included 57 NB patients from amongst 1965 neuroblastic cases in Turkey who experienced a recurrence after multi-model therapy. The cases were diagnosed, risk-stratified, and treated according to the classification system from the International Neuroblastoma Risk Group. Single nucleotide variations in 60 genes were investigated using the Pillar Onco/Reveal Multicancer v4 panel and Pillar RNA fusion panel on the Illumina Miniseq platform. Results: ERBB2 I655V was the most frequent mutation and was found in 39.65% of cases. Anaplastic Lymphoma Kinase (ALK) mutations (F1174L, R1275Q, and rare mutations in the tyrosine kinase domain) were detected in 29.3% of cases. Fusion mutations in NTRK1, NTRK3, ROS1, RET, FGFR3, ALK and BRAF were observed in 19.6% of cases. Conclusions: This study presents valuable mutation data for relapsed and refractory NB patients. The high frequency of the ERBB2 I655V mutation may allow further exploration of this mutation as a potential therapeutic target. Rare BRAF mutations may also provide opportunities for targeted therapy. The role of ABL1 mutations in NB should also be explored further.
The Effect of an Extract of Sappanwood, Protosappanin A and Protosappanin B on Osteogenesis in Periodontitis
Authors: Zheng Xiaodan , Chen Jingqiu , Rao Nanquan , Yang Chun , Liu Juan , Zhang Jun , Li Yanhong
Published: August 2023

Background: Sappanwood is widely used in the prevention and treatment in diseases due to its ability to seal blood vessels, dissipate stasis, and relieve pain. Important monomer components of sappanwood, Protosappanin A (PA) and Protosappanin B (PB) have anti-tumour and antimicrobial medicinal properties. This study investigated the anti-inflammatory and osteogenic differentiation effects of a crude extract of Sappanwood (ESP), PA and PB against periodontitis in periodontal ligament stem cells (PDLSCs). Methods: Oil Red O staining was used to assess the ability of adipocytes to differentiate. Alizarin Red staining was used to assess the capacity to differentiate into osteoblasts. Third-passage PDLSCs were grown in either basic medium alone or basic media with varying doses of ESP (0.0625 mg/mL, 0.03125 mg/mL and 0.125 mg/mL), PA and PB (2.5 µM, 5 µM, 10 µM). The CCK-8 assay was used to measure cell proliferation. Real Time PCR (RT-qPCR) and Enzyme-Linked Immunosorbnent Assay (ELISA) assay were used to measure gene expression. The capacity to differentiate into osteoblasts was evaluated using Alizarin Red staining, and Alkaline Phosphatase (ALP) staining and activity. Results: The development of lipid droplets and mineralized nodules was examined using Oil Red O staining and Alizarin Red staining. Flow cytometry revealed that PDLSCs were CD29 (98.23%) and CD44 (98.81%) positive, but CD34 (0.16%) and CD45 (0.09%) negative. CCK-8 assay showed that ESP at three concentrations (0.03125 mg/mL, 0.0625 mg/mL and 0.125 mg/mL) and 2.5 µM, 5 µM and 10 µM PA and PB had no cytotoxicity at 5 and 7 days (p < 0.05). qRT-PCR and ELISA assay indicated that ESP, PA and PB downregulated the inflammatory cytokines IL-8, IL-6, IL-1β, IL-10 and IL-4 and elevated the mRNA expression of osteogenesis cytokines RUNX2 , OSX and OCN in PDLSCs (p < 0.05). Alizarin red staining, and ALP staining and activity showed that ESP, PA and PB increased mineralized nodules and the ALP content of in PDLSCs (p < 0.05). Conclusions: ESP, PA and PB can reduce the inflammatory response and amplify the osteogenic differentiation of PDLSCs. Therefore, ESP, PA and PB may have potential pharmacological effects in controlling the progression of periodontitis and promoting periodontal tissue regeneration.
Features of Plasma Homocysteine, Vitamin B12, and Folate in Parkinson's Disease: An Updated Meta-Analysis
Authors: Liu Yiti , Gou Maoyuan , Guo Xiaoyan
Published: August 2023

Background: Many studies have shown that the levels of homocysteine (Hcy), vitamin B12 (Vit B12), and folate (FA) are abnormal in patients with Parkinson’s disease (PD), but the results have not been consistent. Therefore, we conducted this meta-analysis to summarize the features of Hcy, Vit B12, and FA in PD patients. Methods: A systematic literature search was conducted on PubMed, Cochrane Library, Web of Science, and Embase databases. Results: A total of 71 studies were included. The analysis showed the following. (1) PD patients had significantly increased Hcy level (standardized mean difference [SMD] 0.80, 95% confidence interval [CI] [0.61, 0.99]; p < 0.001), and decreased Vit B12 (SMD –0.33, 95% CI [–0.43, –0.22]; p <0.001) and FA levels (SMD –0.13, 95% CI [–0.19, –0.06]; p < 0.001) compared to healthy controls. (2) Higher Hcy level (SMD 0.48, 95% CI [0.30, 0.67]; p < 0.001) was found in Dopaminergic medications treated PD patients than in untreated patients. (3) PD patients with cognitive impairment had higher Hcy level (SMD 0.71, 95% CI [0.50, 0.92]; p < 0.001) and lower Vit B12 (SMD –0.22, 95% CI [–0.34, –0.09]; p = 0.001) and FA levels (SMD –0.17, 95% CI [–0.29, –0.04]; p = 0.009) than those with no cognitive impairment. (4) PD patients with neuropathy had significantly increased Hcy level (SMD 0.87, 95% CI [0.43, 1.31]; p < 0.001) and decreased Vit B12 level (SMD –0.40, 95% CI [–0.81, –0.00]; p = 0.049) compared to PD patients with no neuropathy. Conclusions: In conclusion, PD patients may have higher Hcy levels and lower Vit B12 and FA levels than the healthy population. Thus, Hcy, Vit B12, and FA may play a role in cognitive impairment and neuropathy in PD patients.
Astrocytes Are Involved in the Effects of Ketamine on Synaptic Transmission in Rat Primary Somatosensory Cortex
Authors: Yuan Jie , Zhang You , Yang Hao , Cao Song , Luo Yiting , Yu Tian
Published: August 2023

Background: Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used as a general anaesthetic. However, the mechanisms of analgesic/anaesthetic effects induced by ketamine are only partially understood. Previously, studies have demonstrated that various general anaesthetics affect the primary somatosensory cortex (S1), a potential target of general anaesthetics in the central nervous system. However, it is unknown if astrocyte activities affect ketamine’s effects on information transmission in S1 pyramidal neurons. Methods: The whole-cell patch-clamp technique was employed to study the role of astrocytes in ketamine-induced anaesthetic actions. The whole-cell patch-clamp method was used to record the spontaneous postsynaptic currents (SPSCs) of rat S1 pyramidal neurons. We used the glia-selective inhibitor of the aconitase enzyme fluorocitrate (FC), to test if astrocyte activities alter the effects of ketamine on S1 pyramidal neurons. Results: Ketamine lowered the SPSCs of rat S1 pyramidal neurons in a concentration-dependent manner at clinically relevant doses. The concentration-effect curve revealed that ketamine had an EC50 value of 462.1 M for suppressing SPSCs. In rat S1 pyramidal neurons, the glia-selective metabolic inhibitor fluorocitrate (FC), which inhibits the aconitase enzyme, lowered the amplitude and frequency of SPSCs. The inhibitory impact of ketamine on the amplitude and frequency of SPSCs was significantly amplified in the presence of FC. Conclusions: Astrocytes impact the effects of ketamine on pre- and postsynaptic components and play a role in synaptic transmission.
An Open-Label Study of Cranial Electrotherapy Stimulation on Behavioral Regulation in a Mixed Neurodevelopmental Clinical Cohort
Authors: Brandes-Aitken Annie , Gerdes Molly , Hattangadi Neil , Shapiro Kevin A. , Marco Elysa J.
Published: August 2023

Objective: Individuals with neurodevelopmental disorders often report disturbances in the autonomic nervous system (ANS)-related behavioral regulation, such as sensory sensitivity, anxiety, and emotion dysregulation. Cranial electrotherapy stimulation (CES) is a method of non-invasive neuromodulation presumed to modify behavioral regulation abilities via ANS modulation. Here we examined the feasibility and preliminary effects of a 4-week CES intervention on behavioral regulation in a mixed neurodevelopmental cohort of children, adolescents, and young adults. Methods: In this single-arm open-label study, 263 individuals aged 4–24 who were receiving clinical care were recruited. Participants received at-home CES treatment using an Alpha-Stim® AID CES device for 20 minutes per day, 5–7 days per week, for four weeks. Before and after the intervention, a parent-report assessment of sensory sensitivities, emotion dysregulation, and anxiety was administered. Adherence, side effects, and tolerance of the CES device were also evaluated at follow-up. Results: Results showed a 75% completion rate, an average tolerance score of 68.2 (out of 100), and an average perceived satisfaction score of 58.8 (out of 100). Additionally, a comparison between pre- and post-CES treatment effects showed a significant reduction in sensory sensitivity, anxiety, and emotion dysregulation in participants following CES treatment. Conclusions: Results provide justification for future randomized control trials using CES in children and adolescents with behavioral dysregulation. Significance: CES may be a useful therapeutic tool for alleviating behavioral dysregulation symptoms in children and adolescents with neurodevelopmental differences.
Usefulness of Vena Contracta for Identifying Severe Secondary Mitral Regurgitation: A Three-Dimensional Transesophageal Echocardiography Study
Authors: Onishi Hirokazu , Izumo Masaki , Naganuma Toru , Akashi Yoshihiro J. , Nakamura Sunao
Published: August 2023

Background: In secondary mitral regurgitation (SMR), effective regurgitant orifice area by the proximal isovelocity surface area method (EROAPISA) evaluation might cause an underestimation of regurgitant orifice area because of its ellipticity compared with vena contracta area (VCA). We aimed to reassess the SMR severity using VCA-related parameters and EROAPISA. Methods: The three-dimensional transesophageal echocardiography data of 128 patients with SMR were retrospectively analyzed; the following parameters were evaluated: EROAPISA, anteroposterior and mediolateral vena contracta widths (VCWs) of VCA (i.e., VCWAP and VCWML), VCWAverage calculated as (VCWAP + VCWML)/2, and VCAEllipse calculated as π × (VCWAP/2) × (VCWML/2). Severe SMR was defined as VCA ≥0.39 cm2. Results: The mean age of the patients was 77.0 ± 8.9 years, and 78 (60.9%) were males. Compared with EROAPISA (r = 0.801), VCWAverage (r = 0.940) and VCAEllipse (r = 0.980) were strongly correlated with VCA. On receiver-operating characteristic curve analysis, VCWAverage and VCAEllipse had C-statistics of 0.981 (95% confidence interval [CI], 0.963–1.000) and 0.985 (95% CI, 0.970–1.000), respectively; these were significantly higher than 0.910 (95% CI, 0.859–0.961) in EROAPISA (p = 0.007 and p = 0.003, respectively). The best cutoff values for severe SMR of VCWAverage and VCAEllipse were 0.78 cm and 0.42 cm2, respectively. The prevalence of severe SMR significantly increased with an increase in EROAPISA (38 of 88 [43.2%] patients with EROAPISA <0.30 cm2, 21 of 24 [87.5%] patients with EROAPISA = 0.30–0.40 cm2, and 16 of 16 [100%] patients with EROAPISA ≥0.40 cm2 [Cochran–Armitage test; p < 0.001]). Among patients with EROAPISA <0.30 cm2, SMR severity based on VCA was accurately reclassified using VCWAverage (McNemar’s test; p = 0.505) and VCAEllipse (p = 0.182). Conclusions: Among patients who had SMR with EROAPISA of <0.30 cm2, suggestive of moderate or less SMR according to current guidelines, >40% had discordantly severe SMR based on VCA. VCWAverage and VCAEllipse values were useful for identifying severe SMR based on VCA in these patients.
Exercise as the Key to Improve Cardiopulmonary Function in Patients with Valvular Heart Disease: A Systematic Review and Meta-Analysis
Authors: Zeng Liqing , Pi Peng , Zhang Peizhen , Zhu Yu , Yang Lumeng , Wang Chen
Published: August 2023

Background: Valvular heart disease (VHD) is a type of cardiovascular disease with abnormal heart valve structure and/or function and a rapidly growing cause of global cardiovascular morbidity and mortality. Physical inactivity is a problem for patients with VHD, especially after surgery. However, there is no data on the effects of exercise on VHD from large multicentre randomised controlled trials (RCTs). Therefore, we conducted a systematic review and meta-analysis to provide a comprehensive analysis of small RCTs to evaluate the effects of exercise on cardiopulmonary function in patients with VHD and provide an evidence-based medicine basis for developing and guiding the clinical application of exercise in patients with VHD. Methods: We conducted a systematic review and meta-analysis of RCTs. We systematically searched electronic databases (PubMed, Web of Science, Embase, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure [CNKI], China Science and Technology Journal Database [VIP], WanFang Database, and SinoMed [CBM]) for all studies on exercise and VHD from their inception to January 2023. The quality of included studies was assessed using the Cochrane risk-of-bias tool. The primary outcomes were the six-minute walk test distance (6MWD), left ventricular ejection fraction (LVEF), and short-form 36-item health survey (SF-36). Results: This systematic review included 22 RCTs with 1520 subjects (869 men and 651 women). The meta-analysis results showed that exercise significantly improved exercise capacity measured by the 6MWD (mean difference [MD] = 25.54, 95% confidence interval [CI] = 19.98–31.11, I2 = 0%, p < 0.00001), LVEF (MD = 6.20, 95% CI = 4.76–7.65, I2 = 66%, p < 0.00001), and quality of life measured by the SF-36 (physical function: MD = 3.42, 95% CI = 2.12–4.72, I2 = 12%, p < 0.00001; mental health: MD = 3.86, 95% CI = 0.52–7.20, I2 = 68%, p = 0.020; social function: MD = 2.30, 95% CI = 0.64–3.97, I2 = 45%, p = 0.007; bodily pain: MD = 2.60, 95% CI = 0.83–4.37, I2 = 22%, p = 0.004) in patients with VHD compared to healthy controls. Conclusions: This study suggests that exercise can significantly improve cardiopulmonary function, enhance physical and social function, reduce bodily pain, and potentially improve mental health in patients with VHD, providing an evidence-based basis for better recovery in patients with VHD.
Relative Bradycardia and Tachycardia and Their Associations with Adverse Outcomes in Hospitalized COVID-19 Patients
Authors: Bistrovic Petra , Besic Dijana , Cikara Tomislav , Antolkovic Luka , Bakovic Josip , Radic Marija , Stojic Josip , Osmani Besa , Hrabar Mirna , Martinkovic Julija , Delic-Brkljacic Diana , Lucijanic Marko
Published: August 2023

Background: Relative-tachycardia (RT), a phenomenon of unproportionately high heart-rate elevation in response to fever, has been previously attributed to unfavourable outcomes in severe-inflammatory-response-syndrome (SIRS). Relative heart-rate to body-temperature ratio (RHR) and its prognostic associations in patients with severe and critical coronavirus disease 2019 (COVID-19) have not been investigated. Methods: We retrospectively analyzed heart-rate and body-temperature data at admission in patients who were hospitalized due to COVID-19 at a tertiary center from March 2020 to June 2021. After excluding patients with known heart rate affecting medications (beta-blockers and other antiarrhythmics) and atrial fibrillation, a total of 3490 patients were analyzed. Patients were divided into quartiles based on RHR on admission, with patients belonging to the 1st quartile designated as having relative-bradycardia (RB) and patients belonging to 4th quartile designated as having RT. Comparisons with baseline clinical characteristics and the course of treatment were done. Results: There were 57.5% male patients. Median age was 69 years. Most patients had severe or critical COVID-19 at admission. Median heart-rate at the time of hospital admission was 90/min, median body-temperature was 38 °C, and median RHR was 2.36 with interquartile-range 2.07–2.65. RB in comparison to middle-range RHR was significantly associated with older age, higher comorbidity burden, less severe COVID-19 and less pronounced inflammatory profile, and in comparison to RT additionally with higher frequency of hyperlipoproteinemia but lower frequency of obesity. RT in comparison to middle-range RHR was significantly associated with younger age, more severe COVID-19, lower comorbidity burden, lower frequency of arterial hypertension, higher frequency of diabetes mellitus, and more pronounced inflammatory profile. In multivariate analyses adjusted for clinically meaningful parameters, RB patients experienced more favorable survival compared to RT, whereas RT patients experienced higher mortality in comparison to RB and middle-range RHR patients, independently of older age, male sex, higher comorbidity burden and higher COVID-19 severity. Conclusions: Heart rate and axillary temperature are an indispensable part of a clinical exam, easy to measure, at effectively no cost. RT at admission, as a sign of excessive activation of the sympathetic nervous system, is independently associated with fatal outcomes in COVID-19 patients.