bluuebunny/crossref_metadata_2025 huggingface dataset:
EVALUATION OF THE PERFORMANCE OF MAGNETIC RESONANCE IMAGING IN THE EXPLORATION OF THE LOCOREGIONAL EXTENSION OF ENDOMETRIALCANCER: ABOUT 42 CASES
Authors:   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., Bouhia H. , Benmessaoud H. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., Ahmut H. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., Babaouyoub F. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., Lachger A. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., ElMajjaoui S. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., ElKacemi H. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., Kebdani T. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., Hassouni K. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco., Benjaafar N. ,   Department of Radiotherapy, National Institute of Oncology, University Mohammed V of Rabat, Morocco.
Published: March 2023

Introduction and purpose of the study : Endometrial cancer is the third most common gynaecological cancer in Morocco its therapeutic management depends on a precise staging of radiological (myometrial invasion, cervical and ganglionic involvement) and histological (histological type and degree of differentiation)initial workup. This pre-treatment evaluation may over or under treat patients, hence the aim of this work which will evaluate the contribution of magnetic resonance imaging in assessing myometrial invasion and lymph node involvement. Materials and Methods: This is a single-centre retrospective study of a series of patients operated for endometrial cancer who underwent preoperative pelvic MRI in our Institute between January 1, 2014 and January 1, 2018. MRI data were collected from initial reports and compared with postoperative histological data. Results and statistical analysis: 42 patients were included. Deep myometrial infiltration was found in 21 patients on MRI versus 25 patients on histology, with a sensitivity of 64% and specificity of 70.58% a positive predictive value of 76.19% and a negative predictive value of 57.14%. Pelvic and/or lomboaortic adenopathies were found in 11 patients on MRI compared to 6 patients on Histology with a sensitivity of 66.66% and specificity of 81.57%, a positive predictive value of 36.36% and a negative predictive value of 93.93%. Conclusion: According to our study, MRI is not sufficiently accurate to detect the percentage of myometrial invasion and to identify the lymph node status.
Face Spoofing Detection using Inception-v3 on RGB Modal and Depth Modal
Authors: Arti Yuni , Arymurthy Aniati Murni
Published: March 2023

Face spoofing can provide inaccurate face verification results in the face recognition system. Deep learning has been widely used to solve face spoofing problems. In face spoofing detection, it is unnecessary to use the entire network layer to represent the difference between real and spoof features. This study detects face spoofing by cutting the Inception-v3 network and utilizing RGB modal, depth, and fusion approaches. The results showed that face spoofing detection has a good performance on the RGB and fusion models. Both models have better performance than the depth model because RGB modal can represent the difference between real and spoof features, and RGB modal dominate the fusion model. The RGB model has accuracy, precision, recall, F1-score, and AUC values obtained respectively 98.78%, 99.22%, 99.31.2%, 99.27%, and 0.9997 while the fusion model is 98.5%, 99.31%, 98.88%. 99.09%, and 0.9995, respectively. Our proposed method with cutting the Inception-v3 network to mixed6 successfully outperforms the previous study with accuracy up to 100% using the MSU MFSD benchmark dataset.
The potential of coconut waste as green roof materials to improve stormwater runoff
Authors: Romali Noor Suraya , Ardzu Fatin Afiqah Binti , Suzany Muhamad Nurfaizal
Published: March 2023

Urbanization is one of the leading causes of urban flooding as rapid development produces more impervious areas in cities. The application of green roofs is regarded as an effective technology to minimize the adverse effects of urban development. The stormwater management capacities of green roofs have been extensively acknowledged, and they can retain rainfall and detain runoff. Nevertheless, Malaysia has experienced few green roof applications, and only limited literature is available concerning such topics. Additionally, the incorporation of waste and recycled material in green roof designs must be considered to ensure such projects benefit the environment as well as the economy. Therefore, the construction of a green roof utilizing recycled waste materials was attempted. An extensive green roof was constructed using beach morning glory and creeping ox-eye plants as vegetation layers, along with coconut waste, i.e., coconut fiber and coconut shell, as the medium for the filter and drainage layer, respectively. According to the results, the use of recycled coconut waste materials in the green roof operations reduced the peak flow by as much as 86%, while the use of commercial materials led to a reduction of 67%.
Thomasa Reida interpretacja „teorii idei”. Pytanie o bezpośredni przedmiot poznania
Authors: Kucharski Dariusz
Published: March 2023

Thomas Reid, twórca szkockiej szkoły zdrowego rozsądku, głosił tezę, że wszystkie wcześniejsze systemy filozoficzne obciążone są tym samym „grzechem pierworodnym” – przyjęciem (w różnych formach) reprezentacjonistycznej teorii spostrzeżenia zmysłowego. Nazywał ją „teorią idei”, której konsekwencją miało być oddzielenie podmiotu i przedmiotu poznania nieusuwalną „zasłoną idei”. Konstruowanie własnej filozofii poprzedził analizą historii tego zagadnienia od starożytności do czasów sobie współczesnych, usiłując wykazać zasadność swego stanowiska. Celem artykułu jest odpowiedź na pytanie o trafność poglądów Reida, wyrażonych w przyjmowanej teorii spostrzeżenia. Chodzi więc przede wszystkim o pogląd charakterystyczny dla tradycji arystotelesowsko-tomistycznej, tradycyjnie interpretowany jako prezentacjonizm, oraz poglądy Kartezjusza dotyczące statusu „idei” w procesie poznawania tzw. świata zewnętrznego. Przeprowadzone analizy wskazują jednocześnie na uproszczenia w Reidowskiej interpretacji poglądów jego poprzedników na naturę spostrzeżenia oraz na cechy krytykowanych teorii, które w pewnym stopniu usprawiedliwiają tę krytykę.

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Zgłoszono: 28/10/2022. Zrecenzowano: 24/11/2022. Zaakceptowano do publikacji: 16/12/2022.
Turismo educativo en la Universidad Nacional Agraria La Molina: Un análisis de la experiencia educativa
Authors: Lindo Angulo Teresa , Valle Basto Daniel Fernando , Chávez Salas Jorge Mario
Published: March 2023

La gestión de la experiencia del visitante implica tanto aspectos emocionales, como educativos y sociales. Durante esta investigación, se entrevistó a 219 personas: 9 de la Oficina de Relaciones Públicas de la UNALM y de 7 instituciones educativas que visitan la Universidad Nacional Agraria La Molina (32 adultos y 178 estudiantes) para determinar los aspectos sociales y educativos que influyen en la experiencia de los visitantes a la UNALM. Durante el año 2017, se tomaron cuestionarios y entrevistas para obtener información, los que fueron analizados en grupos: (a) personal UNALM, (b) docentes – administrativos de los colegios, y (b) estudiantes de colegio. En el caso de los docentes y los estudiantes, se analizó el factor del colegio de origen (público – privado) para determinar las diferencias entre estos tipos de centros educativos para esta investigación. Los principales resultados de esta investigación, realizada en un contexto sin COVID-19, fueron los siguientes: (a) los docentes y el personal administrativo de los colegios reconocieron que las visitas educativas tienen los fines pedagógicos-académicos como su principal motivación (la salida educativa, con actividades académicas concretas, fue la más valorada por los colegios privados); y (b) los estudiantes se motivan principalmente por el «paseo escolar» (recreación) antes que por la experiencia educativa de la visita.
MUM1L1 as a Tumor Suppressor and Potential Biomarker in Ovarian
Cancer: Evidence from Bioinformatics Analysis and Basic Experiments
Authors: Zhang Lu , Wu Xue , Fan Xue , Ai Hao
Published: March 2023

Background:

Ovarian cancer (OC) is the most prevalent gynecologic malignancy, with
high mortality rates. However, its pathogenesis remains unclear. The current study aimed to explore
potential biomarkers and suppressor genes for diagnosing and treating OC.

Methods:

Biochemical and bioinformatics approaches were used to detect differentially expressed
genes (DEGs) in ovarian tissues via integration analysis. Kaplan-Meier plot analysis was performed
to assess progression-free survival and overall survival according to DEGs. Then, we constructed
a protein-protein interaction (PPI) network based on data from the STRING database to
identify the related target genes of DEGs. Finally, DEGs regulating the proliferation, migration,
and invasion of SKOV3 cell lines were validated via in vitro experiments.

Results:

Four DEGs (MUM1L1, KLHDC8A, CRYGD, and GREB1) with enriched expression in
ovarian tissues were explicitly expressed in the ovary based on an analysis of all human proteins.
MUM1L1 had high specificity, and its expression was higher in normal ovarian tissues than in OC
tissues. Kaplan-Meier plot analysis showed that a high MUM1L1 expression was associated with
longer progression-free survival and overall survival in OC. Based on the PPI analysis results,
CBLN4, CBLN1, PTH2R, TMEM255B, and COL23A1 were associated with MUM1L1. In vitro
studies revealed that MUM1L1 overexpression decreased the proliferation, migration, and invasion
ability of SKOV3 cell lines. Meanwhile, MUM1L1 knockdown had contrasting results.

Conclusion:

MUM1L1 is a tumor suppressor gene and is a potential biomarker for diagnosing and
treating OC.
Effect of a Training Intervention Based on the Theory of Planned Behavior on the Pregnancy Intention in Women with One Child: A Training Trial
Authors: Moghadam Masoumeh Farshid , Khorsandi Mahboobeh , Khalajinia Zohreh , Zamanian Maryam , Klobas Jane Elizabeth
Published: March 2023

Background:

Having an only child has positive and negative consequences for the health of the child, mother, and family. However, when one-child families become the norm, the risks of negative long-term impacts increase. In Iran, couples now prefer to have one child. This paper reports on an investigation into the effectiveness of training based on the theory of planned behavior (TPB) on the pregnancy intention in women with one child.

Methods:

The trial was conducted in 2019 with 102 women with one child, who was supported by the Health Centers in Qom, Iran. They were randomly divided into two groups: TPB theory-based training (n=52) and control (routine healthcare training, n=50) groups. ANCOVA was used to compare the groups' post-training pregnancy intention and its theoretical antecedents.

Results:

Three months post-training, participants in the TPB group had higher pregnancy intention (η2 = .4, P<0.001), attitude to having a second child (η2 = .41, P<0.001), subjective (perceived) norm for having a second child (η2 = .08, P<0.004), and perceived control for having a second child (η2 = .35, P<0.001). The TPB-based training intervention increased women's awareness of the consequences of having an only child significantly more than routine training (P<0.001).

Conclusion:

Health center training can increase women's intention to have a second child. In this trial, theory-based training resulted in stronger pregnancy intention than participation in routine training. As health centers in Iran update their programs, this trial highlights the value of course design based on established theory.
Bioactive Phytochemicals and Molecular Mechanisms of Artemisiae
capillariae against Drug Induced Liver Injury based on Network
Pharmacology
Authors: Shan Wen , Yang Zhiping , Zhao Yan , Hu Yan , Yan Ran , Wu Xi , Huang Junzi , Lin Musen
Published: March 2023

Background:

Artemisiae capillariae (Yinchen, YC) is a well-known herbal medicine used to treat drug-induced liver diseases, while the bioactive phytochemicals and pharmacological targets of YC remain unclear.

Objective:

The study aimed to probe the key active components in YC and determine the potential molecular mechanisms of YC protect against DILI

Method:

In this study, we first delved into the active chemicals and targets of YC, identified potential anti-AILI targets for YC, mapped the components-targets network, performed protein-protein interaction (PPI) analysis, gene ontology (GO) enrichment, and Kyoto encyclopedia of genes and genomes (KEGG) signaling pathway analyses of the action targets. This led to figure out the liver protective mechanism of YC against AILI. Analyzing the molecular docking of key targets, binding domain of ingredients and targets reveals the effective interaction, and the binding energy explains the efficiency and stability of the interactions.

Results:

Network analysis identified 53 components in YC; by systematic screening 13 compounds were selected, which were associated with 123 AILI-related genes. The core ingredients were quercetin, capillarisin and Skrofulein, and the identified crucial genes were AKT1, TNF, and IL6. The GO and KEGG pathway enrichment analysis results indicated that the anti-AILI targets of YC mainly take a part in the regulation of oxidative stress and immune, with related signaling pathways including PI3K/AKT and IL17. Furthermore, the binding pockets of YC bioactive ingredients and key targets were revealed, and the binding ability was proved by molecular docking analysis.

Conclusion:

This study has revealed the potential bioactive molecules and mechanism of YC in AILI and provided a possible strategy for the identification of active phytochemicals against drug-induced liver injury.
MiR-12200-5p Targets Multiple Members of Wnt Signaling Pathway to
Inhibit Osteoblast Differentiation and Bone Formation
Authors: Li Hui , Yin Chong , Li Jingjia , Huang Qian , Huai Ying , Chu Xiaohua , Ji Mili , Tian Ye , Qian Airong , Li Danming
Published: March 2023

Background:

Osteoporosis is widespread and has become an emerging problem in the elderly. MicroRNAs could affect osteoblast differentiation and further regulate the occurrence of osteoporosis by targeting osteogenic differentiation signaling pathways. Our screening study found that miR-12200-5p simultaneously targeted six important factors within the Wnt signaling pathway (Apc, Tcf4, Tcf7, Wnt3a, Wnt5a, and Lrp6), indicating that miR-12200-5p might function as a strong regulator of this pathway. Since the Wnt pathway exists as one of the most essential pathways for osteogenic differentiation, miR-12200-5p may have an important role in the development of osteoporosis.

Objective:

This study intended to explore the regulatory role and corresponding mechanism of miR-12200-5p in osteoblast differentiation

Methods:

We investigated the differentiation of osteoblast after the treatments of miR-12200-5p mimic and inhibitor. The interactions between miR-12200-5p and its target genes were also detected. Furthermore, the rescue effect of miR-12200-5p inhibitor on osteoporosis was evaluated using an ovariectomized osteoporosis mouse model.

Results:

MiR-12200-5p significantly inhibited osteoblast differentiation, and bound with the 3’-UTR sequences of its target genes (Apc, Tcf4, Tcf7, Wnt3a, Wnt5a, and Lrp6) to reduce the expressions of these genes. The inhibition of miR-12200-5p would almost fully alleviate postmenopausal osteoporosis.

Conclusion:

MiR-12200-5p could strongly repress osteoblast differentiation and bone formation by targeting multiple members of the Wnt signaling pathway simultaneously. The study supplemented the theoretical and experimental basis for researching the mechanism of osteogenic differentiation and inspired the development of novel therapeutic strategies for osteoporosis.
Design and Analysis of a Breast Biopsy Robot Based on TRIZ Theory
Authors: Du Haiyan , Liu Hongle
Published: March 2023

Background:

In recent years, more and more medical robots have formally stepped into clinical applications and are gradually being accepted by patients. Magnetic resonance image (MRI)-guided breast intervention robot is the most advanced technology for breast cancer treatment. Still, the very limited working space within the MRI scanner restricts the development of breast intervention robots.

Objective:

In this paper, a compact breast biopsy robot in MRI environment is proposed based on TRIZ theory.

Methods:

The structure of the robot is optimized by using the curvilinear principle and the asymmetry principle of TRIZ theory to obtain a modified cartesian coordinates robot for breast biopsy. The coordinate systems of the robot are established using D-H method. Next, 3D visualization simulation of the robot is performed by SimMechanics of MATLAB, and then kinematic simulation and workspace simulation analysis are carried out.

Results:

The simulation results show that motion space of the end effector of the robot meets the requirements of breast intervention surgery, and the robot structure is simple and effective.

Conclusion:

In this paper, a compact breast biopsy robot in MRI environment is proposed. Through the Simulink module of MATLAB to analyze its workspace, it is obtained that its working range is 250mm × 300mm × 200mm, which can cover any position in breast tissue. At the same time, the simulation results of the workspace also show that the structure optimization of the breast biopsy robot based on TRIZ theory is reasonable.
Assessment Methods for Various Hepatotoxicities and their Experimental Models: A Review
Authors: Upadhyay Prabhat Kumar , Singh Sonia , Semwal Bhupesh Chander , Vishwakarma Vishal Kumar
Published: March 2023

Globally, liver diseases are a significant public health concern, necessitating the development of new chemicals that can aid in their treatment or prevention. As a result, scientists have been looking for natural and artificial compounds with hepatoprotective effects. The key objective of this manuscript is to provide details on several techniques and models for determining liver toxicity. The data has been collected for the manuscript from various e-sources such as Publons, Pubmed, Scopus, ScienceDirect, and Web of Science. The development of novel pharmaceuticals involve several steps, beginning with identifying the pharmacological effects in cellular and animal models and concluding with demonstrating their safety and efficacy in humans. The scientific literature mentions several in vitro, ex vivo, and in vivo experimental paradigms for evaluating hepatoprotective drugs. This review's main objective is to outline the key traits, advantages, and disadvantages of each model, as well as the most commonly used hepatotoxic substances (acetaminophen, t-BuOOH, d-galactosamine, ethanol, thioacetamide), biochemical parameters helpful in assessing liver damage in various models, and the most frequently used hepatotoxic substances overall.
Drugs Designed for Degradation in the Environment Post Use
Authors: Sydnes Magne Olav
Published: March 2023

Accumulation of pharmaceuticals in the environment due to slow mineralization in nature is a
growing pollution problem affecting organisms and animals and humans in the long run. When pharmaceuticals
are antibiotics, the problem is twofold since the buildup of such compounds in the environment
also fuels the development of antibiotic resistance. Building weak structures of biologically active compounds
is one way of facilitating the quicker degradation of the drug in the environment after the drug has
been excreted from the patient subsequently performing its function. The emergence of the process of
photodegradation post-excretion of the pharmaceutical from the patient is one method that is under development,
which will facilitate a quicker breakdown of the drug. Another method to enable this is hydrolysis,
which is pH-dependent and involves making up of compounds that hydrolyze quicker under certain
pH conditions. To enable the ongoing efforts in making pharmaceuticals to be more benign, this focused
review showcases examples from research on antimicrobial agents and anticancer agents.
Povijest neuroanestezije
Authors: Murselović Tamara , Kovač Nataša
Published: March 2023

Razvoj neuroanestezije neraskidivo je povezan s razvojem neurokirurgije. Zbog spoznaje da neuroanestezija ima svoje specifičnosti zbog same prirode neurokirurgije, kao zasebno polje anestezije razvija se na prijelazu 19. u 20. stoljeće. Tek napretkom tehnologije i znanosti, napose u drugoj polovici 20. stoljeća, neuroanestezija iskazuje svoj puni potencijal. Klinička struka prolazi svoj put od spoznaje da fiziološke parametre (puls i tlak) treba kontinurano pratiti i zapisivati, zahvaljujući dr. Harveyu Cushingu, do praćenja učinka anestetika na vrijednosti EEG-a, intrakranijalnog tlaka, cerebralnog protoka krvi i metabolizma mozga. Zahvaljujući brojnim vrsnim stručnjacima, kao što su Albert Faulconer, John Mitchenfelder, James Cotrell i Roy Cucchiara, neuroanestezija je postala uža specijalnost unutar anesteziologije, sa svojim društvima, svojim časopisima i stručnim skupovima.
Miskoncepcije i stavovi o fizici kod studenata fizioterapije
Authors: Lekić Andrica , Mance Diana
Published: March 2023

Cilj: Cilj rada je predstaviti rezultate ispitivanja studentskih stavova o fizici i njihove povezanosti s usvajanjem koncepata u fizici. Ispitanici i metode: U istraživanju je sudjelovalo 89 studenata prve godine Preddiplomskog stručnog studija Fizioterapija, Fakulteta zdravstvenih studija Sveučilišta u Rijeci. Ovom istraživanju, prethodilo je ispitivanje učenika sedmih i osmih razreda jedne riječke osnovne škole (N = 92). Upitnik je sadržavao tvrdnje kojima su izražavani stavovi ispitanika studenata o fizici. Drugi dio upitnika činile su tvrdnje među kojima su bile i česte miskoncepcije u fizici. Miskoncepcije smo podijelili na one koje nastaju zbog jezičnog miješanja pojmova iz svakodnevnog života i znanosti, one koje proizlaze iz korištenja neispravnih pretpostavki za objašnjenje svakodnevnog iskustva te one koje se temelje na nerazumijevanju znanstvenih pojmova i koncepata. Rezultati: Studenti u najvećoj mjeri imaju neutralan stav prema fizici. Postoji statistički značajna razlika u zastupljenosti miskoncepcija prema uzroku njihova nastanaka (Hi-kvadrat; P < 0,001). Najzastupljenijima su se pokazale miskoncepcije nastale poistovjećivanjem izraza iz svakodnevnog života i znanosti, tzv. žargonske miskoncepcije (58 % slučajeva). Utjecaj studentskih stavova na učestalost miskoncepcija pokazao se statistički značajnim za stavove koji ukazuju na to da su ispitanici više usmjereni na memoriranje gradiva i kvantitativne manipulacije nego na uspješno usvajanje znanstvenih pojmova i koncepata. Zaključci: Primjena napredne tehnologije u terapiji i dijagnostici u okviru medicinske skrbi ukazuje na sve veću potrebu za znanjem iz fizike kod studenata zdravstvenih i medicinskih studija. Studenti shvaćaju važnost fizike u svojem obrazovanju i većinom ne iskazuju negativan stav prema fizici. Određene vrste miskoncepcija zadržavaju se tijekom čitavog obrazovnog procesa. Zato treba sprječavati nastanak neznanstvenih koncepata, odnosno ako oni već postoje, treba ih što ranije detektirati i aktivno raditi na njihovom uklanjanju.
Neonatal Intestinal Obstruction Caused by a Perforated Duodenal Web
Authors: Dukić Andrija , Lugonjić Danijel , Bilić Čače Iva , Bosak Veršić Ana
Published: March 2023

Aim: To report the clinical courses of two patients with intestinal obstruction caused by duodenal web, who were diagnosed with this rare congenital anomaly at Clinical Hospital Center Rijeka in a span of 5 months. Case report: One of the patients was prenatally suspected to have duodenal obstruction due to ultrasonographic findings, while the other showed signs of obstruction by not tolerating oral intake from the second day of life (DOL). Ceasing enteral feeding, placing a nasogastric tube and introducing intravenous hydration and parenteral nutrition was performed as initial management. Abdominal ultrasonography, abdominal radiography, upper gastrointestinal contrast study and contrast enema were performed but showed no signs of obstruction. Both patients showed improvement in tolerating oral intake over the next few days. However, the first patient did not tolerate meals exceeding 15 mL of infant formula, and the second patient again did not tolerate any oral intake from the 15th day of life. A broad diagnostic workup was repeated but did not show conclusive evidence of obstruction regarding the first patient. Esophagogastroduodenoscopy found duodenal obstruction of unknown origin regarding the second patient. Laparotomy was performed on the 19th and 25th DOL, respectively. Duodenal web was visualized and excised in both patients following duodenotomy. Postoperative recovery was orderly with minor nonsurgical complications. The patients were discharged from hospital on the 21st and 36th postoperative day, respectively. Conclusions: Diagnosing a perforated duodenal web is often challenging because of possible intermittent nature of its symptoms. Exploratory laparotomy is sometimes required to reach diagnosis.
Perforacija crijeva uslijed kompresivnog učinka pseudociste gušterače – prikaz slučaja
Authors: Šimić Iva , Hauser Goran
Published: March 2023

Cilj: Prikazati specifičnu komplikaciju kroničnog pankreatitisa, odnosno perforaciju tankog crijeva uslijed kompresivnog učinka pseudociste te različite načine dijagnostike i liječenja. Prikaz slučaja: Pacijent u dobi od 60 godina zaprimljen je na hitni prijam zbog difuznih bolova u abdomenu, najviše lokaliziranih u žličici te je naveo da obilno povraća tamnosmeđi sadržaj nakon svakog unosa vode i hrane. Fizikalnim pregledom ustanovljena je palpatorna bolnost stijenke abdomena i defans stijenke. Prilikom hospitalizacije napravljen je CT abdomena koji je ukazao na egzacerbaciju kroničnog pankreatitisa. U prilog egzacerbaciji kroničnog pankreatitisa govorila je velika cistična tvorba (195 × 109 × 158 mm). U pseudocistu je postavljen dren radi kontinuiranog pražnjenja. Nakon perkutane drenaže i dalje je perzistirala pseudocista veličine 21 × 18 mm te je ostvarila komunikaciju s manjom cističnom tvorbom iz burse omentalis. Sljedećeg dana ERCP tehnikom postavile su se dvije pankreatične proteze zbog stenoziranog ductusa pancreaticusa na prijelazu između glave i repa gušterače. Pred otpust pacijenta UTZ abdomena pokazao je reziduu pseudociste veličine 30 × 30 mm. Tjedan dana nakon otpusta pacijent dolazi na hitni prijam radi povraćanja, smanjenog apetita, anergije i mršavljenja. Daljnjim pretragama ustanovila se perforacija tankog crijeva kao posljedica adhezivnog ileusa i peritonitis. Stanje se pacijenta tijekom dva dana pogoršavalo – bio je anergičan, usporen, smanjenog stanja svijesti te je preminuo na odjelu intenzivnog liječenja. Zaključak: Ileus i perforacija tankog crijeva vrlo su rijetke komplikacije pseudociste gušterače, te je do danas ovo drugi opisan slučaj perforacije tankog crijeva uslijed kompresivnog učinka pseudociste. Simptomi ileusa kod egzacerbacije kroničnog pankreatitisa trebali bi pobuditi sumnju na kompresivne smetnje cistične tvorbe u abdomenu.
Volumetric integro-differential equations in diffraction and eigenvalue problems (r e v i e w)
Authors: Davidovich M. V.
Published: March 2023

Volumetric integral and integro-differential equations are considered that describe problems of diffraction by three-dimensional bodies with given macroscopic permittivity and magnetic permeability, as well as problems on free vibrations of such bodies. Similar equations are obtained for waveguide structures: hollow shielded waveguides with dielectric filling, dielectric waveguides (optical beamguides), photonic-crystal waveguides. Dominantly stationary linear electromagnetic problems are considered. Non-stationary and nonlinear problems are mentioned casually. Numerical results are given for oscillations H01delta and H011 of a cylindrical dielectric resonator, for waves of a rectangular dielectric waveguide and a plasmonic waveguide, dispersion in a photonic crystal, and diffraction by a rectangular dielectric cylinder. Keywords: ...
Transverse components of the electromagnetic field in a waveguide with modulated in space and in time magnetodielectric filling
Authors: Gevorkyan E. A.
Published: March 2023

The propagation of transverse magnetic (TM) and transverse electric (TE) electromagnetic waves in a regular ideal waveguide of arbitrary cross section is considered. It is assumed that the permittivity and permeability of the magnetodielectric filling of the waveguide are functions that depend on the coordinate and time. Analytical expressions for the transverse components of the magnetic and electric vectors of the TM- and TE-fields in the waveguide are obtained from the system of Maxwell equations. They are expressed in terms of the longitudinal components of the electric and magnetic vectors, which describe the transverse magnetic and transverse electric fields in the waveguide. For the above longitudinal components of the electric and magnetic vectors, the wave equations are given, which are also obtained from the system of Maxwell's equations. Keywords: Maxwell equations, propagation of electromagnetic waves, waveguide with modulated filling, transverse components, Helmholtz equations, Dirichlet and Neumann problems.
An Investigation of Social Emotional Learning Skills in Primary Schools in Terms of Some Variables
Authors: Usakli Hakan
Published: March 2023

In this study, the social-emotional learning skills of the students attending the fourth and fifth grades of primary school were examined in terms of gender, class, parental association, assertiveness, aggression, and submissiveness variables. As a measurement tool in the study, it consists of four dimensions and twenty-one items developed by Baydan (2010). Behavioral Tendency Scale for Children, which was developed by Deluty (1979) and adapted to Turkish by Usakli (2006), was used. The findings of the study revealed that there were significant differences in the social-emotional learning skills of the students attending the fourth and fifth grades in terms of gender, class, parental association, assertiveness, aggression, and submissive variables. In future studies, it may be about giving social emotional learning skills training in different grade levels by associating it with assertiveness training.
El tráfico de migrantes internacionales en México: diferencias entre pollero, coyote y traficante de migrantes
Authors: Casillas R. Rodolfo
Published: March 2023

Objetivo: caracterizar y diferenciar tres tipos de actores sociales de México que trasladan migrantes internacionales: pollero, coyote y traficante de migrantes. Metodología: revisión de artículos en revistas académicas especializadas en migración para explicitar qué se sabe de dichos actores y entrevistas a migrantes, a traficantes de estos y a personal de albergues humanitarios. Resultados: se encontraron diferencias y similitudes entre los tres actores. Valor: la distinción hallada en esta investigación puede servir para diseñar políticas públicas que estén asociadas con el fortalecimiento de los tejidos sociales, puesto que se distingue entre los agentes sociales cohesionadores y los que responden solo al mercado. Conclusiones: los actores sociales en cuestión son diferenciables conforme a dos categorías centrales: cohesión social y lógica de mercado.
Computational Docking Study of the Phytochemical Constituent, Silybin (Silybum marianum) against SARS-CoV-2 Omicron Variant Spike Glycoprotein: An In-silico Approach
Authors: Bansal Poonam , Sharma Varruchi , Panwar Anil , Kumar Raman , Sharma Aanchal , Ramniwas Seema , Dey Abhijit , Chandran Deepak , Dhama Kuldeep , Sharma Anil K
Published: March 2023

SARS-CoV-2 is continually evolving with the emergence of new variants with increased viral pathogenicity. The emergence of heavily mutated Omicron (B.1.1.529) with spike protein mutations are known to mediate its higher transmissibility and immune escape that has brought newer challenges for global public health to contain SARS-CoV-2 infection. One has to come up with a therapeutic strategy against the virus so as to effectively contain the infection and spread. Natural phytochemicals are being considered a significant source of bioactive compounds possessing an antiviral therapeutic potential. Being a promising anticancer and chemo-preventive agent, Silybin holds a significant potential to be used as a therapeutic. In the present study, molecular docking of Silybin with Omicron spike protein (7QNW) was carried out. Molecular docking results showed greater stability of Silybin in the active site of the Omicron spike protein with suitable binding mode of interactions. The study reveals that Silybin has the potential to block the host ACE2 receptor-viral spike protein binding; thereby inhibiting the viral entry to human cells. Therefore, Silybin may be further developed as a medication with the ability to effectively combat SARS-CoV-2 Omicron.
Analysis of Robust Immune Response among Diabetic and Non-Diabetic Individuals against SARS-CoV-2 Vaccination
Authors: Venkatesan Balamurali , Vajravelu Leela Kakithakara , Ravi Sujith , Thulukanam Jayaprakash , Muthamilan Om Lokesh
Published: March 2023

The pandemic on SARS-CoV-2 infection has adversely impacted mankind all over the globe and more importantly, amidst individuals having Type-2 diabetic mellitus (T2DM) as well as among those who produce SARS-CoV-2 intricacies. Humoral and T cell-mediated immunity are adaptive immunity has a pivotal role to play in removing pathogens, comprising SARS-CoV-2. The infected cells are being eliminated by the primarily cytotoxic CD8+ T cells as well as certain antibodies in opposition to SARS-CoV-2 among humoral immunological responses possess the capacity for neutralizing this virus or by eliminating the infected cells with the support of cytotoxic in order to manage the progression of the disease. This cross-sectional study was carried out between January 2022 to December 2022. The serum samples were used to analyze SARS-CoV-2 total Ab among individuals having and not having T2DM and several metabolic risk factors like hypertension using WANTAI SARS-CoV-2 Total Ab ELISA Kit. There were 354 individuals, of which 141 (39.8%) had T2DM and 213 (60.2%) were nondiabetic patients. T2DM showed reduced antibody levels (average 5 AU/ml) than those without diabetes (average 12 AU/ml). SARS-CoV2 total antibody levels are considerably lower in hypertension patients (8 AU/ml) over those who are normotensive (14 AU/ml). The present study implies that the continuous monitoring of the total antibody profile of SARS-CoV-2 that may be a practical strategy to help individuals with T2DM and hypertension to determine their need of precautionary doses for sustaining SARS-CoV-2 vaccines by producing immunity for protection against infections.
Mathematical Analysis of Car & Bridge Interaction Using Law of Physics for Vibration Formulation
Authors: Gavel Avinash , Suryawanshi Dr. H. R. , Singh Sudheshwar
Published: March 2023

Abstract: Vibration is the natural & inherent property of resistance against disturbance in a Elasto-Plastic materials. The structure are often designed in the manner that they can sustain and maintain their superstructure under the influence of dead and live loads with the minimum disturbance of their inertia. The super-structures and tunnels are generally placed on the surface of load carrying columns in the form of simply supported beams. The integration method of which generates a continuous system which is the bridge super structure. So that Natural Frequency (time function Fn) and Response Function (space function) can be generated and programmed in MATLAB.
Customer Perception Towards Life Insurance in Vadodara City
Authors: Rao Dr. Mayur , Shah Aryan , Shah Vrunda
Published: March 2023

Abstract: Life insurance is an essential financial product that provides protection and financial security to individuals and their families in the event of unforeseen circumstances such as death or disability. However, people's perception towards life insurance varies widely depending on their personal beliefs, experiences, and cultural backgrounds. Some individuals perceive life insurance as a necessary and valuable investment, providing peace of mind and security for their loved ones in the event of their untimely demise. Others may view life insurance as an unnecessary expense or a product only for the wealthy. Factors such as age, income, education, and cultural background can also influence people's perceptions of life insurance. For instance, younger individuals may perceive life insurance as less important, while older individuals may view it as a necessity. Similarly, people with lower incomes may see life insurance as unaffordable or a low priority compared to other financial needs. Overall, understanding people's perceptions towards life insurance is important for insurance companies to develop appropriate marketing strategies and products that meet the needs of different customer segments. It is also crucial for individuals to educate themselves about the benefits of life insurance and how it can provide financial security and peace of mind for themselves and their loved ones.
A Portable Wireless Head Movement Controlled Human-Computer Interface for People with Disabilities
Authors: Barve Saurabh , Beedkar Prof. Megha , Gawale Poonam , Jadhav Rajan
Published: March 2023

Abstract: This paper describes about an economical head operated computer mouse for people with disabilities. It focuses on the invention of a head operated computer mouse that employs one tilt sensor placed in the helmet to determine head position and to function as simple head-operated computer mouse. The system uses accelerometer based tilt sensor to detect the user's head tilt in order to direct the mouse movement on the computer screen. Clicking of mouse is activated by the user's eye brow movement through a sensor. The keyboard function is designed to allow the user to scroll letters with head tilt and with eye brow movement as the selection mechanism. Voice recognition section is also present in the head section to identify the small letters which are pronounced by the paralyzed user. This system was invented to assist people with disabilities to live an independent professional life.
АНАРХИЗМ - НИЙГЭМ-УЛС ТӨРИЙН АЯДУУ ҮЗЭЛ БАРИМТЛАЛ БОЛОХ НЬ
Authors: Г.Цэнд-Аюуш  , Н.Ариунаа
Published: March 2023

социально-политическое течение, обосновывающее целесообразность и необходимость реализации "анархии", то есть освобождения личности от какой бы то ни было экономической, социальной, политической духовно-идеологической власти. Это освобождение личности анархизм усматривает в преодолении сложившегося на определенных этапах общественного развития отчуждения человека от государства, власти, собственности путем ликвидации этих социальных институтов, в отрицании какого бы то ни было государства, отстаивании идей создания федерации автономных ассоциаций производителей.
АРДЧИЛАЛ БА БОЛОВСРОЛЫН ХАРИЛЦАН ХАМААРЛЫН АСУУДАЛ
Authors: С.Базарпүрэв  , Б.Насанбат
Published: March 2023

“Ардчилал” хэмээх энэхүү ойлголтыг улс төр, философи, эрх зүй, ёс зүйн гээд олон талаас нь тайлбарлаж болно. Энэ удаад бид уг ойлголтыг боловсролын үйл ажиллагаанд хамааруулан тайлбарлахыг зорьж байна. Үүний тулд прагматизм, тэр дундаа Ж.Дьюигийн үзэл санаа, арга зүйг удирдлага болгов. Ж.Дьюи бол ардчилал ба боловсролын харилцан хамаарлыг анхлан тайлбарласан сэтгэгчийн нэг бөгөөд боловсролыг ардчилах,боловсрол дахь ардчиллын үүрэг, ач холбогдлын талаар өгүүлсэн олон бүтээл бичиж үлдээсэн судлаач юм.Тэрээр өөрөө өөртөө бүрэн найдаж, өөрийгөө авч явж чаддаг, үүрэг хариуцлага хүлээж чаддаг, эрх чөлөөтэй, нийгмийн идэвхтэй гишүүн хэрэгтэй юу? үгүй юу? хэмээх асуултыг ардчилал, боловсролын аль алинтай нь холбогдох асуулт мөн тул судлаачид үүнийг анхаарах хэрэгтэй хэмээн үзжээ. Түүний тайлбараар ийм иргэн хүн нь нийгэмд хэрэгтэй тул тэдгээрийг өөрт нь бүрэн итгэл хүлээлгэж, өөрийнх нь бие даасан байдлыг хүндэтгэж, тохирсон үүрэг, хариуцлага оноож, оюун санааны болон үйлдлийн эрх чөлөө олгосон сургалтын үйл ажиллагаагаар бий болгож чадна гэж үзжээ. Эндээс л боловсрол ба ардчиллын харилцан хамаарал эхэлдэг. Энэ утгаар ардчилал ба боловсролын харилцан хамаарлын асуудал нь орчин үед сургуулийг байр тоног төхөөрөмжөөр хангах, багшаар хангах, мөнгө санхүүгээр дэмжих тухай асуудлуудаас дутахааргүй үнэ цэнэтэй.
МОНГОЛ УЛСЫН ИХ ХУРЛЫН ГИШҮҮНИЙГ СОНГОГЧДЫН САНАЛААР ЭГҮҮЛЭН ТАТАХ ЭРХ ЗҮЙН ОРЧНЫГ БҮРДҮҮЛЭХ АСУУДАЛД
Authors: Ц.Ганболд  , С.Жавхлан
Published: March 2023

In an effort to improve discipline and accountability of elected members of the Mongolian parliament, calls for legislative recall mechanisms have gained momentum in recent years. Though such practice is fairly uncommon, the notion of creating a mechanism which would allow voters to be able to exercise control over elected officials and hold those who have failed to represent their constituents' best interests accountable has become increasingly popular. This paper aims to highlight key factors to be taken into consideration if such a procedure is to be legislated.
Г.В.Ф. Гегелийн улс төрийн сургаал
Authors: А.Жамбал  , Ж.Жаргал
Published: March 2023

Германы агуу их гүн ухаантан, улс төрийн сэтгэгч Георг Вильгельм Фридрих Гегель (1770-1831) Штутгарт хотод санхүүгийн томоохон албан тушаалтны гэр бүлд төржээ. Тюбингений их сургуульд шашны онолын факультетийг төгссөн ба хожим нь Берлиний их сургуульд философийн тэнхимийг толгойлох болсон байна. Түүний үзэл санаа Францын хөрөнгөтний агуу их хувьсгалын нөлөөгөөр төлөвшжээ. Гегель улс төр, эрх зүйн асуудлыг амьдралынхаа бүтээн туурвих бүхий л шатанд чухалчлан авч үзжээ. Түүний улс төрийн ба эрх зүйн сургаал нь “Оюун санааны феноменологи” (1807), “Философийн шинжлэх ухааны нэвтэрхий толь” (1821), “Түүхийн философийн лекцүүд”, ялангуяа “Эрх зүйн философи”(1821) хэмээх томоохон зохиолуудад тусчээ. Гегелийн эрх зүйн философи ба улс төрийн сургаал бол дэлхий нийтийн хэмжээний улс төрийн ба эрх зүйн сэтгэлгээний түүхэнд том, онцгой байр суурь эзэлдэг, утга агуулгаараа нэн баялаг, нарийн нийлмэл сургаал мөн болно.
УЛСТӨРИЙН СОЁЛ: ИНСТИТУЦИОНАЛЬ ХЭМЖЭЭС
Authors: Ё.Довчин
Published: March 2023

Улстөрийн соёлын үзэл баримтлал улстөр хэмээх үзэгдлийг бүхэлд нь цогцоор авч үзэх бололцоо олгодогоороо давуу талтай байдаг. Хэрэв улстөрийн соёлыг мэдрэмж, мэдлэг,үнэлэмж болж хувирсан улстөрийн систем хэмээвээс тэр нь тухайн нийгмийн улстөрийн хүрээний өнгөрсөн 26, өнөөгийн амьдралыг өөртөө тольдон харуулдаг гэж болно. Энэ утгаар улстөрийн соёлын институциональ бүрэлдүүлбэр, түүний дотор монголын эдүгээгийн улстөрийн соёлыг институциональ хандлагын үүднээс задлан ялгаж шинжлэх нь судалгааны чухал чиглэл байх учиртай.
МОНГОЛ ДАХЬ АВИЛГАЛЫН ТҮВШИНД НӨЛӨӨЛӨГЧ ХҮЧИН ЗҮЙЛС: БАРИМТ БИЧГИЙН БА ТООН СУДАЛГААНЫ АНАЛИЗ
Authors: Ж.ТӨРТОГТОХ  , Д.Оюунчимэг  , Ч.Өлзийсайхан
Published: March 2023

Энэхүү өгүүлэлд МУИС-ийн Орчин үеийн улс төрийн судалгааны төвөөс эрхлэн гүйцэтгэсэн “Авилгалыг дэмжигч болон хориглогч хүчин зүйлсийн судалгаа” төслийн хүрээнд хийгдсэн 1/ авилгалын талаарх баримт материалын контент, контекст анализ; 2/ 8 аймаг, нийслэлийн 6 дүүргийн төлөөлөл бүхий хот, хөдөөг хамарсан нийт 500 гаруй түүвэр бүхий анкетын судалгааны үр дүнг толилуулах болно. Баримт бичгийн контент-контекст анализын үр дүнд тулгуурлан авилгалд эерэгээр болон сөргөөр нөлөөлөгч хүчин зүйлсийн хэмжүүр гарган бүлэглэн авч үзсэн. Үүнийхээ үндсэн дээр асуулгын аргад түшиглэн нийт 500 гаруй анкетаар тоон судалгааг явууллаа. Түүвэр судалгааны дүнг тооцож гаргахдаа авилгалыг өөгшүүлэхэд болон хориглоход нөлөөлөх улс төр, эрх зүй, эдийн засаг, ёс суртахууны зэрэг хүчин зүйлсүүдийг хэд хэдэн дэд хүчин зүйлсээр тооцож гаргасан болно. Судалгааг 2006 оны YII-YIII сард хийж, судалгаанд оролцогсдын өгсөн мэдээллийг тоолж шалган, компьютерт шивж, статистикийн тоололтын боловсруулалтыг SPSS 11.5. программаар гүйцэтгэв.
МОНГОЛЫН УЛС ТӨРИЙН СИСТЕМИЙН БҮРДЭЛЖИЛТ
Authors: Ю.Атар
Published: March 2023

Монголын улс төрийн системийн түүхэн уламжлал бол Төв Азийн нутаг дэвсгэр дээр олон үеийн турш оршин сууж, хөдөлмөрлөн бүтээж ирсэн манай ард түмний эх түүхийн нэгэн тодорхой хэсэг бөгөөд монголчуудын оюуны соёлын төлөвшин боловсорч ирсэн түүхэн төлөв, залгамж холбоог илтгэн харуулна. Улс төрийн систем гэдэг бол төрөө байгуулж байгаа болон сэргээж байгаа улс орны түүхэн хөгжлийг илэрхийлэгч онцгой шинж болдог байна. Тэр нь нийгмийн ололт, хөгжлийн үзүүлэлт төдийгүй мөн төрийг хөгжүүлж хамгаалах, улс төрийн системийг төгөлдөржүүлэхэд чиглэсэн үзэл суртал, улс төр, ёс суртахууны тодорхой шалгууртай байдаг бололтой.
Pengaruh Maleic Anhydride (MAH) Terhadap Kualitas Papan Komposit Termodifikasi Sebagai Produk Daur Ulang
Authors: Handayani Suci , Riyandini Vina Lestari , Lisha Sri Yanti
Published: March 2023

Pertumbuhan penduduk menyebabkan terjadinya peningkatan produksi limbah yang dihasilkan khususnya limbah plastik. Di pulau Sumatera kontribusi limbah plastik menepati posisi kedua setelah limbah organik yaitu 17% dengan jenis terbanyak adalah limbah plastik jenis Polyprophylene (PP). Disamping itu produksi minyak kelapa sawit menghasilkan limbah tandan kosong yang hanya dibuang ke lingkungan karena tidak dimanfaatkan dengan maksimal sehingga merusak lingkungan. Salah satu solusi untuk memberdayakan potensi limbah plastik dan tandan kosong kelapa sawit adalah dengan mendaur ulangnya menjadi papan komposit. Untuk meningkatkan kualitas papan komposit tersebut dan sesuai dengan standar, maka dilakukan penambahan zat aditif Maleic Anhydride (MAH). Penelitian ini dilakukan dengan menvariasikan komposisi MAH sebanyak 5%, 10%, dan 15% dari total berat TKKS dan Plastik PP (40% : 60%). Selanjutnya dilakukan pengujian sifat fisik dan mekanik berdasarkan pada SNI 03–2105–2006. Dari hasil pengujian papan komposit yang dihasilkan sudah memenuhi SNI 03–2105–2006 kecuali untuk nilai MOE masih jauh dibawah standar. Secara keseluruhan papan komposit yang menghasilkan nilai terbaik adalah pada penambahan MAH 15% dimana hasil uji sifat fisiknya (kerapatan 0,72 g/cm3, pengembangan tebal 0%, kadar air 1,6%) dan sifat mekaniknya (MOR 139 kgf/cm2, dan MOE 13.965,42 kgf/cm2).

Kata kunci:  TKKS, PP, MAH, dan Papan Komposit
Digital inklusion, nye initiativer og gamle tekstsamlinger
Authors: Karoline Liv Vildlyng  , Max Odsbjerg Pedersen
Published: March 2023

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