bluuebunny/crossref_metadata_2025 huggingface dataset:
A New Design of Large-format Streak Tube with Single-lens Focusing System
Authors: Tian Liping , Shen Lingbin , Chen Lin , Li Lili , Tian Jinshou , Chen Ping , Zhao Wei
Published: October 2021

Streak tubes with large-format and high spatial resolution are central to mm-spatial-resolved STIL detection system and hyperspectral resolved ICF experiment. In this paper, we established a large-format streak tube with a three-coaxial-cylindrical single-lens focusing system, a spherically curved photocathode and phosphor screen model in CST Particle Studio. The temporal and spatial resolution were calculated and mimicked based on the Monte-Carlo sampling method in static and dynamic mode. The simulated results show that the static spatial resolution reaches 50 lp/mm over the whole 50 mm effective photocathode length, and the physical temporal resolution is better than 45 ps. Furthermore, in dynamic working mode, the streak tube can achieve spatial resolution of 10 lp/mm and temporal resolution of 60 ps. The simulation results will be used to guide the design and production for large-format with high spatial resolution streak tube development.
Grief: Aetiology, Symptoms and Management
Authors: Pop-Jordanova Nada
Published: October 2021

Grief is a process provoked as a response to different losses, such as death, loss of job, relationship breakdown, some unexpected life events and changes, etc. The experiences of loss and bereavement are very individual. Even though loss is expected, the person feels traumatized, especially if death is provoked by violence, natural disasters, or war. This pandemic, like other disasters (wars, tsunami, earthquakes, floods, etc.) has provoked intensive reactions of grief, reactions that could persist for years. The core symptoms of grief are described in the ICD-11 and DSM-5 manuals.

The term “complicated grief” in the medical sense refers to a superimposed process that alters grief and modifies its course for the worse. Prolonged grief disorder (PGD) is characterized by normal grief symptoms, but these are symptoms that remain too intense for too long of a period.

This article is a review of the manifestations and duration of grief in different occasions, and it is based on over 50 published papers, and discoveries in the Medline and Psych-Net databases.

Commonly described reactions to grief are: shock, disbelief or denial, a high level of anxiety, distress, anger, sadness, insomnia, and a loss of appetite. As predictors for a high/slow decreasing trajectory of grief process are: female gender, reported symptoms of depression before the traumatic event, and higher scores on avoidance. However, grief is transient, even as we are is in the midst of its clutches. People should expect to fluctuate between moments of sadness and mourning, and moments of acceptance, or even happiness for being alive. Researchers suppose that when a crisis passes; most people will be able to bounce back and move on with their lives.
New DXA Diagnostic Indexes of Abdominal Obesity
Authors: Stratrova Slavica Shubeska , Mishevska Sasha Jovanovska , Efremovska Ljudmila , Bitoska Iskra , Spasovski Dejan
Published: October 2021

Aim: Cushing’s syndrome (CS) is associated with weight gain and extreme central, visceral, abdominal obesity which is confirmed with dual-energy X-rays absorptiometric (DXA) diagnostic cut-off point (CP) values of central obesity indexes (COI), determined as an android to gynoid tissue and fat mass ratios. These best differentiate CS from non-CS obese women matched with CS according to their age and BMI. The aim of this study was to determine the CP values of new DXA indexes of central, abdominal obesity as a ratio of android and trunk to legs as well as trunk and legs to total tissue and fat mass that best differentiate CS and matched non-CS obese women in order to confirm central abdominal obesity, and to determine their normal CP values that best differentiate healthy non-obese women from CS and non-CS obese women, and to exclude abdominal obesity completely.

Material and Methods: DXA indexes of abdominal obesity, calculated as а ratio of regional body fat and tissue mass compartments android to legs (A/L), trunk to legs (Tr/L), trunk to total (Tr/To) and legs to total (L/To) values were determined among 4 groups. Each group consisted of 18 women: 1st group of CS, 2nd group of obese women (O1) not different according to their age and BMI from CS, 3rd group of obese women (O2) with higher BMI of 35 ± 1.2 kg and a 4th group of non-obese, healthy women (C) with a normal BMI. Diagnostic accuracy (DG) of CP values of DXA indexes of abdominal obesity and indexes of normal body fat distribution (BFD) were determined.

Results: A/L, Tr/L, Tr/To, and L/To DXA indexes were significantly different between CS and O1 as well as between non-CS women O2 compared to O1 and C. These indexes had a highly significant correlation among each other and also in relation to their BMI (p < 0.0001). A/L-Tm CP value of 0.3 best differentiated the CS from group O1, with the highest DG of 100 % and an A/L-Fm CP value of 0.26 differentiated them with a DG of 94.44% and sensitivity of 100 %. An A/L-Tn CP value of 0.23 and an A/L-Fn CP value of 0.25 best differentiated CS and C as well as O2 and C for the highest DG of 100 %.

Conclusions: DXA indexes A/L, Tr/L, Tr/To and L/To values were significantly different among the four groups. These values correlated significantly among them and with their BMI in non-CS groups, thus confirming a BMI increase association with a more pronounced abdominal BFD. An A/L-Tm CP value of 0.3 and an A/L-Fm CP value of 0.26 were discovered as the best DXA diagnostic indexes of extreme abdominal obesity in CS and these could also be used in discovering abdominal BFD in non-CS obese women with metabolic syndrome (MS). An A/L-Tn CP value of 0.23 and an A/L-Fn CP value of 0.25 were discovered as the best DXA diagnostic indexes of normal BFD which completely excluded abdominal obesity.
The Environmental Performance of Traction Batteries for Electric Vehicles from a Life Cycle Perspective
Authors: Sandrini Giulia , Có Beatrice , Tomasoni Giuseppe , Gadola Marco , Chindamo Daniel
Published: October 2021

The aim of this review article is the analysis of the results obtained from the scientific literature concerning all the phases that make up the life cycle of traction batteries for electric vehicles, in order to evaluate the associated environmental impact. In this regard, some scientific articles dealing with LCA studies concerning electric vehicles, with particular reference to batteries, will be examined. The revision of these articles will provide a general framework for the production, use and recycling phases of traction batteries. In particular, different parameters that influence the outcome of the LCA studies will be shown, parameters on which we can then act to improve the environmental impacts of the transition from internal combustion vehicles to electric mobility. These parameters are represented by the chemistry of the battery considered, aspect at the centre of the discussion, by the specific energy and efficiency of the battery pack, by the durability of the latter, but also by other aspects, such as the energy mix considered (both for the production phase, for the use phase and for recharging) and the functional unit chosen for the study, which determines a different approach, related to the analysis of a specific problem or aspect rather than another. Finally, the usefulness of the recycling practice and the related problems will be shown. In fact, the recycling must be perfected according to the battery chemistry in question to obtain benefits and better reduce environmental loads.
Fetuin-A as a Marker of Insulin Resistance
Authors: Yamasandhi Ganavi P , Dharmalingam Mala
Published: October 2021

Fetuin-A is a glycoprotein which helps in the regulation of metabolism. It is an early marker of insulin resistance (IR). The aim of this study was to evaluate the role of Fetuin-A as a predictive biomarker in cases of newly detected type 2 diabetes (NDD). The study involved 60 NDD and 60 Normal Healthy Controls (NHC). All the demographics and anthropological characteristics were noted. Fasting blood samples were drawn and various biochemical parameters were analyzed. The homeostatic model assessment of insulin resistance (HOMA-IR) and the quantitative insulin sensitivity check index (QUICKI) score was calculated. Chisquare, student T-test and Mann Whitney U tests were employed to associate and compare the mean and median between the NDD and NHC groups. Pearson's and Spearman’s correlation analysis were employed to examine the relationship of Fetuin-A levels with parametric and nonparametric variables. The independent predictors of Fetuin-A was determined by employing multiple forward linear regression. Fetuin-A was significantly high in NDD compared to NHC (1323 vs. 306.98 mcg/mL; p<0.001). Majority of NDD patients demonstrated IR based on the HOMA-IR (88.33% vs. 66.67%) and QUICKI score (96.67% vs. 85%). The multiple linear regression analysis showed that systolic blood pressure, age and QUICKI score were independently associated with Fetuin-A (p value <0.01). Fetuin-A may be used as a biomarker to detect NDD. Therefore, early detection of Fetuin-A levels in NDD gives an opportunity for suitable patient management.
The Effectiveness of Legal Protection on The Wage of Workers in Small Medium Enterprises in The Culinary Sector
Authors: Laily Nur , Syarief Elza , Fitri Winda , Sudisno Sudisno
Published: October 2021

The problem of inequality related to wages for workers in a society that we often encounter must be resolved. So, this study aims to determine the effectiveness of the application of the Labor Law on wages of Small and Medium Enterprises workers in the culinary sector in Batam, as well as to see the obstacles that occur in the implementation of wages of Small and Medium Enterprises workers in the culinary sector of Batam City. This reserach is empirical research that is based on events that have occurred in the field regarding the application of the law through a series of observations, interviews with competent government officials, small and medium enterprises in the culinary sector. This research shows that the wages received by most of the Small and Medium Enterprises workers in the culinary sector in Batam City are not feasible, such as the absence of a work agreement as mandated by the Labor Law. This can occur because the Manpower Law does not explicitly accommodate the interests of Small and Medium Enterprises workers in the culinary sector, then the government's lack of awareness in preparing skilled workers, and the low quality of education of workers.
The Role of Micro Small and Medium Enterprises (MSMEs) in the Recovery of the National Economic
Authors: Lubis Ikhsan
Published: October 2021

The application of Micro, Small and Medium Enterprises (MSMEs) has a considerable influence in contributing and developing as the main supporter in the implementation of National Economic Recovery (NER) programs. This paper leads to a qualitative descriptive approach. This research has been developed using a literature review approach. This conceptual approach is carried out by referring to sources, namely books, journals and the internet.” The research design uses descriptive qualitative which can be interpreted that a series of activities aimed at getting the results of the research as it is at the conclusion.  problems that exist with existing policies in order to realize the program from (NER) and as a result of the Covid19 pandemic, there are still some obstacles and problems in the protection and empowerment of cooperatives and MSMEs.
La ventanilla única nacional para el comercio como la herramienta de la facilitación del comercio
Authors: Nikiforovich Sidorov Víctor , Víctorovna Sidorova Elena
Published: October 2021

Trade facilitation is promoting international trade by facilitating the flow of goods and services by reducing the cost and time of cross-border trade transactions and thus eliminating procedural barriers to trade. To achieve this objective, trade facilitation as a diversified concept includes several instruments. One of the main measures that seeks to promote trade facilitation is a single window for trade. The notion and main model of the national single window bases on the Recommendation No. 33 and Guidelines on Establishing a Single Window and the World Trade Organization's Trade Facilitation Agreement. Studies show that the countries realize the application of the single window of different forms and there is no only model of the national single window. In a few countries they created several systems like Port Community System, the customs single window, the maritime single window instead of creating the one national single window. To understand the nature of the national single window it is important to analyze the perspectives and the features of the national single window that distinguishes the single window to other systems in international trade.
FINANCING OF STATE SOCIAL PROGRAMS: NEW APPROACHES AND TOOLS
Authors:   Pereiaslav–Khmelnytskyi Hryhorii Skovoroda State Pedagogical University, Tropina Valentyna Borysivna
Published: October 2021

A characteristic feature of the current stage of development of society is the socialization of economic systems and the subordination of the economic function of the state to social goals. State social programs play an important role in achieving them. The current state of their implementation in Ukraine significantly raises issues related to the formation of an effective system of financial support for state targeted social programs. The limited traditional sources of funding for state targeted programs actualizes the search for alternative forms and ways of their financial support. Attention to this issue was paid in the works of such researchers: L. Alekseenko, L. Barannyk, A. Barrientos, A. Boyko, V. Danylyshyn, O. Danyliuk, I. Yevdokimova, V. Zayats, V. Zyuzina, L. Lysyak, E. Libanova, O. Luta, O. Malinowska, N. Morel, J. Palme, N. Pigul, O. Ponomarenko, I. Prikhno, O. Staff, O. Tulai, B. Shulyuk and others. Today's realities require new approaches to solving the problems of financial support of state targeted social programs. The task of this study is to develop theoretical and methodological foundations for the formation and use of state social programs, to identify problematic issues in the financing of social programs in Ukraine and to develop recommendations for their solution. The article proposes directions for modernization of the financial system of implementation of these programs using the latest approaches and tools. Among the wide range of new forms and methods of financing state social programs, it is recommended to focus on public-private partnerships, public social procurement; financial investment in social projects; financial instruments of social orientation, fiscal incentives.
INTERNATIONALIZATION AND COOPERATION OF THE HIGHER EDUCATION SYSTEM OF UKRAINE IN THE CONDITIONS OF GLOBAL CHALLENGES
Authors:   Kyiv National University of Technologies and Design, Bebko Svitlana Viktorivna
Published: October 2021

Modern higher education takes an important role in facilitating mobility, including youth, innovation, economic growth, capitalization of human potential. Given the instability and severe challenges of today, there is an increasing need to strengthen partnerships between higher education institutions at both the national and international levels, conducting a common educational policy, forecasting and planning activities for sustainable development and strengthening competitive positions in the market of educational services. This highlights show the need for theoretical and methodological rethinking of the features of new forms and approaches to ensure the effectiveness of internationalization of higher education in Ukraine and cooperation of partner institutions, which should become effective mechanisms for achieving goals and solving complex problems, including access to education, quality and efficiency, capitalization of human potential. In addition, with the beginning of quarantine measures, significant changes are taking place in the direction of internationalization of higher education. It has been proven that internationalization and cooperation in higher education, international learning, including joint online learning, internships, student mobility as tools of interaction has significant potential for involving a significant number of people in intercultural learning on a global scale. The need for effective internationalization is associated with significant opportunities for universities with limited resources to implement their intentions. Finding a compromise will promote transnational cooperation partnerships both inside the country and internationally, and the main features of internationalization should be sustainability, interdisciplinarity, creativity, openness. Achieving these components will have a positive effect not only for the higher education sector, but also for society as a whole.
ENVIRONMENTAL POLLUTION AS A COMPONENT OF THE GLOBAL ECOLOGICAL CRISIS: NATIONAL LEVEL
Authors:   National University “Chernihiv Polytechnic”, Minina Oksana , Shevchenko Olha Stepanivna ,   Taras   Shevchenko   National   University «Chernihiv Collegium», Moroz Yevhiniia Andriivna ,   LLC «Technology Ukraine»
Published: October 2021

The problem of environmental pollution is exacerbated every year and is undoubtedly a global problem. However, the effectiveness of its solution depends on the efforts of individual countries, their awareness of the impending threat, responsible and systematic control, continuous monitoring and study of trends. Given the urgency and scale of coverage, the impact on health and quality of life, interdependence and interdependence globally, environmental pollution needs to be addressed gradually and simultaneously in each country, ultimately ensuring a synergistic global impact. Numerous modern studies on this issue have significantly supplemented the theoretical and practical basis of environmental and economic sciences, formed not only the conceptual apparatus, but also added analytical tools, but the world continues to grow, the world's population grows, consumption increases, production scale and, consequently, pollution environment, which is an integral part of the anthropogenic impact of society. That is why the analysis, identification of trends, modeling of pollution processes and possible consequences remains relevant today. The main task of this study is to monitor the environment of Ukraine in terms of pollution of its main components, identify major sources and trends, build trends to further predict the development of the situation, which will be an information base for management decisions aimed at leveling the negative consequences for our country and its population, and for the global ecological system. The analysis conducted in the work revealed unfavorable trends in environmental pollution in Ukraine and the problem of insufficient funding for environmental measures, especially in terms of environmental investment. The attention of the state, taking into account the requirements of the outside world, the degree of interdependence of countries on each other's behavior in the environmental sphere, should be focused on solving this problem.
Ações preventivas em enfermagem ao HIV/AIDS na atenção primária de saúde
Authors: Araújo Elaine Freitas de , Albuquerque Jaqueline Moreira de , Farias Nelciene da Silva Guimarães , Vetorazo Jabneela Vieira Pereira
Published: October 2021

Objetivo: Esclarecer como vem ocorrendo as ações preventivas em enfermagem ao HIV/AIDS na Atenção Primária de Saúde (APS). Métodos: Revisão integrativa da literatura, de abordagem qualitativa/qualitativa, que tomou por bases de dados a Biblioteca Virtual em Saúde (BVS), bem como a Biblioteca Eletrônica Científica Online (Scielo) e a Acervo+, no espaço temporal entre 2016 a 2021, que discutissem os aspectos relacionados às ações de prevenção ao HIV na APS. Resultados: Encontraram-se 124 artigos nas bases de dados, e após a leitura dos títulos foram separados 92 artigos que passaram pela análise dos critérios de inclusão, sendo escolhidos 32 para leitura na íntegra e ao final foram selecionados 14 artigos para subsidiar a presente revisão de literatura. Considerações Finais: Os(as) enfermeiro(as) na APS atuam de maneira basilar no processo de prevenção de doenças, pois, podem criar estratégias para sensibilizar, informar e empoderar os pacientes e assim diminuir a exposição ao HIV/AIDS, por meio de atividades como rodas de conversa, palestras, execução de testes rápidos, educação em saúde, campanhas, entre outros.
Trauma: característica sociodemográficas das vítimas e aspectos clínicos-assistenciais de sua ocorrência em hospital de urgência
Authors: Paulo Gabriela Maria Lara de , Colares Carlos Matheus Pierson , Margarida Mykaella Cristina Araújo , Silva Andressa Rodrigues da , Silva Ana Caroliny da , Xavier Lais Lara Silva , Pereira Thainara Lorraine Costa e Silva , Silva Suzy Aparecida Luiz da , Sousa Thais Vilela de , Melchior Lorena Morena Rosa
Published: October 2021

Objetivo: Descrever as características sociodemográficas das vítimas de trauma bem como aspectos circunstanciais e clínico-assistenciais de suas ocorrências em um hospital de urgência referência em traumas no centro-oeste do país. Métodos: Trata-se de um estudo com abordagem quantitativa do tipo transversal descritiva. A amostra foi composta de 1148 prontuários compostos por pacientes de ambos os sexos, com idade igual ou superior a 18 anos, admitidos na sala vermelha de centro de trauma, no período de janeiro a dezembro de 2019. Resultados: A prevalência dos traumas foi em adultos jovens, com faixa etária entre 18 a 24 anos (21,43%), do sexo masculino (71,60%). A maioria ocorreu nos dias do final de semana e no período noturno, quanto a gravidado dos traumas, 72,47% foram classificadas como moderado. A principal causa dos traumas foram os acidentes automobilísticos (49,47%) que, em sua maioria, envolveram motocicletas. Em 36,76% dos casos ocorreram politraumas e o sítio anatômico mais acometido foram os membros inferiores (21,73%). Conclusão: Há uma preocupante prevalência de trauma em adultos jovens e homens, tendo como principal etiologia o transporte terrestre, com ênfase nas motocicletas. Os resultados sinalizam a necessidade de intensificar as medidas políticas, sociais e educativas.
Clinical case of fungal uveitis in a patient who underwent COVID-19
Authors:   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Tereshchenko A.V. , Trifanenkova I.G. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Ilina Y.L. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Yudina N.N. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Noskova N.H. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Erohina E.V. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution
Published: October 2021

Purpose. To analyze a clinical case of fungal uveitis in a patient who has undergone COVID-19. Material and methods. A patient born in 1962 was admitted to the Kaluga branch of the MNTK with complains of blurred vision. From the anamnesis: in the first half of 2020, he was treated at the Kaluga branch of the MNTK with a diagnosis of complicated cataract, highly complicated myopia, PCRD, CCRD, pigmentary glaucoma; in the autumn of 2020, he suffered a coronavirus infection complicated by severe bilateral interstitial pneumonia, he was in the intensive care unit for 2 weeks. Results. During examination of the patient, the clinical picture and data of objective methods indicated the development of bilateral uveitis in the patient. A course of anti-inflammatory therapy was prescribed, and positive dynamics were achieved. But there was a sharp deterioration on the 10th day. Concilium was held: a fungal etiology of uveitis was suspected. The anterior chamber was washed, material from the anterior chamber was taken for bacterial culture. At the 3rd day the results of bacterial culture showed the growth of Candida albicans fungi. A multistage complex medical and surgical treatment was carried out. The outcome is encouraged however, the observation time is insufficient to draw final conclusions. Conclusion. The incidence of COVID-19 remains high, so ophthalmologists should remain vigilant, collect a careful anamnesis and expect an increase of the number of patients with intraocular fungal infection. Key words: uveitis; fungal infection; COVID-19.
Pelaksanaan Peran Kantor Wilayah Kementerian Hukum Dan Ham Sumatera Barat Dalam Rangka Harmonisasi Peraturan Daerah Provinsi Sumatera Barat Tahun 2019
Authors: Gusman Delfina , Alsyam Alsyam , Nazmi Didi
Published: October 2021

Kantor Wilayah Kementerian Hukum dan HAM setiap daerah memiliki peran yang penting dalam hal harmonisasi peraturan-peraturan daerah yang sesuai dengan hierarki perundang-undangan. Harmonisasi hukum menjadi suatu upaya untuk menciptakan suatu keselarasan, kesesuaian serta kecocokan hingga keseimbangan terhadap norma-norma hukum. Salah satu instansi yang memiliki peran ini adalah Kementerian Hukum dan HAM hingga setiap daerah.Hasil penelitian bahwa Dalam kaitannya dengan Tugas dan fungsi Kanwil bahwa pada dasarnya tugas dan fungsi Kanwil dalam penyusunan peraturan daerah sudah sejalan dengan ketentuan UU Nomor 12 tahun 2011 tentang Pembentukan Peraturan Perundang-undangan, namun keterlibatan Kanwil Kementerian Hukum dan HAM hanya terbatas dan pasif menunggu pemerintah daerah maupun DPRD mengikutsertakan. Dalam upaya meningkatkan peran Kanwil Kementerian Hukum dan HAM dalam proses penyusunan peraturan daerah perlu disusun suatu aturan untuk pelaksanaan yang mengatur secara rinci mekanisme penyusunan peraturan daerah yang melibatkan Pemerintah Daerah, DPRD maupun Kanwil Kementerian Hukum dan HAM, dengan adanya payung hukum yang komprehensif diharapkan dapat mendorong optimalisasi penyusunan peraturan Daerah yang berkualitas.
Tradução para Libras Escrita: relatos sobre o processo de tradução e implementação do SignWriting em um sistema de revistas científicas para surdos
Authors: Ronnie Fagundes de Brito , Bárbara Neves Salviano de Paula , Beatriz Albuquerque Rodrigues , Breno Rodrigues Cardoso de Moura , Bruno Panerai Velloso , Daniele Miki Fujikawa Bózoli , Diego Abadan , Felipe de Castro Teixeira , Iudi Zurba Melgarejo , Josenilson da Silva Mendes , Lais Rovani Teixeira , Madson Barreto , Miguel de Castro Silva , Milton Shintaku , Noriko Lúcia Sabanai , Pablo Valério Polônia , Renato Rojas , Rosilene Paiva Marinho de Sousa , Rubens Ramos de Almeida , Tom Min Alves , Vera Lúcia de Souza e Lima
Published: October 2021

This research is the result of a historical drift, in which chance led to interact and better understand deafness and the deaf. of form applied, Modelo para Tradução de Sistema de Revistas de Científicas em Libras (SWOJS) proved to be interdisciplinary in addressing linguistic and technological aspects in supporting communication in Libras, in order to describe a model with processes and tools aimed at supporting their written representation. The chapters are ordered so that, initially, contextualize issues about deafness, in order to present below linguistic and terminological issues, factors that underlie the translation choices, in which, finally, the resources are described technologies that supported the translation of the software. In addition to a project on accessibility, this study is about of an initiative that sought to affirm a space for culture deaf is heard and respected, adding diversity to the society of the knowledge in which we live.
The City of Erasure
Authors:   , Wilson-Cartwright Rory
Published: October 2021

In 2011 the Banks Peninsula experienced an unprecedented natural disaster. This disaster, anearthquake, measured larger in vertical ground acceleration that any recorded prior. As youcan imagine, the architecture surrounding the epicentre was devastated. It was not just build- ings that were lost, but all of their associations; memories, experiences, intimate and personal objects. Life was erased from the surface of the earth.

Amongst the chaos, trauma and destruction, it was a particular personal experience that actedas the catalyst for this thesis. After they demolished our home, I struggled to recall the eventsthat took place within its walls. I could not separate the real from the imagined. It was only when I stumbled upon the working drawings that I was able to position myself within my memories and reflect on the erasure that caused my memories to change. This experience led me to contemplate, what role do memories have on our understandings of a city? How can architectural drawings facilitate these relationships?

This thesis does not set out to fix the issues that natural disasters cause; rather, it aims to further our understanding of therole that memory plays in our perceptions of urban environments. It uses the implications of erasure as material for speculative architectural investigations. These investigations are achieved through three clear sets of design experiments ascending in scale and complexity; the first, an installa- tion, the second, a series of medium-scale architectures, and the third, a large public building. These design experiments use speculative architectural drawings as a translational tool for ephemeral phenom- ena, helping to bridge the divide between cerebral and operational perceptions. This research aims to further our understanding of these complex phenomena in order to expand upon our own spatial and architec- tural intelligence through explorations of memory and erasure.
Analisis Penggunaan Metode Eksperimen terhadap kemampuan Anak Usia Dini Dalam Melakukan Analisa Sebab –Akibat
Authors: Sue Yohana , D.H Dwi Prasetiyawati , Khasanah Ismatul
Published: October 2021

Pendidikan Anak Usia Dini ( PAUD) adalah pendidikan yang diselenggarakan dengan tujuan memfasilitasi pertumbuhan dan perkembangan anak secara menyeluruh atau menekankan pada perkembangan seluruh aspek kepribadian anak. Pembelajaran anak usia dini sangat beragam karena pada dasarnya anak memiliki rasa ingin tahu yang tinggi dan didukung oleh orang dewasa termasuk guru dan orangtua. Anak USIA Dini diperbolehkan belajar apa saja sesuai dengan perkembangan termasuk belajar mengenal konsep sebab akibat dengan metode eksperimen yang merupakan suatu kegiatan pemberian penhalaman secara langsung untuk mengembangkan keterampilan proses agar mampu menjelajahi serta memahami alam sekitar. Konsep sebab –akibat adalah kemampuan abstrak yang dimiliki setiap anak mengenai apa yang terjadi, hal ini mulai dari lingkungan terdekat, seiring perkembangan, kemampuan ini dapat menngkat ketahap pengertian mengenai proses yaitu suatu hubungan timbal balik peristiwa terjadi. Metode eksperimen adalah suatu cara penyajian materi pembelajaran dimana anak secara aktif mengalami dan membuktikan sendiri tentang apa yang dipelajari. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif. Hasil penelitian dibagi dalam tiga aspek yaitu aspek pengamatan, aspek pemahaman konsep dan aspek menyimpulkan. Dari hasil penelitian dapat disimpulkan bahwa penggunaan metode eksperimen mampu dipahami oleh anak usia dini terutama mengenai konsep sebab – akibat.Kata Kunci: Anak Usia Dini, Metode Eksperimen, Konsep sebab –akibat.
ANALISIS KETERKAITAN PEMBELAJARAN BAHASA INGGRIS SEBAGAI MUATAN LOKAL DENGAN KURIKULUM TEMATIK KELAS IV SD MUHAMMADIYAH 01 KOTA TEGAL
Authors: Fadhella Riziqsiwi Fhafha , Budiman Muhammad Arief , Reffiane Fine
Published: October 2021

Penelitian ini bertujuan untuk mendeskripsikan pembelajaran bahasa Inggris sebagai muatan lokal di SD, mendeskripsikan ada atau tidaknya keterkaitan antara pembelajaran bahasa Inggris dengan kurikulum tematik yang terdapat paa materi pembelajaran tematik kelas IV SD Muhammadiyah 01 Kota Tegal. Jenis penelitian ini adalah penelitian kualitatif deskripstif. Populasi penelitian adalah guru kelas IV, guru bahasa Inggris, siswa kelas IV, dan orang tua siswa kelas IV SD Muhammadiyah 01 Kota Tegal tahun ajaran 2020/2021. Metode pengumpulan data dalam penelitian ini  diperoleh melalui wawancara, kuesioner, dan dokumentasi. Hasil analisis dari kuesioner dan wawancara guru dan siswa kelas IV SD Muhammadiyah 01 Kota Tegal telah menunjukkan bahwa adanya perbedaan materi pada pembelajaran tematik dan pembelajaran bahasa Inggris di kelas IV, yaitu: Materi pekerjaan pada pembelajaran tematik. Pada  pembelajaran bahasa Inggris, mataeri pekerjaan hanya membahas suatu pekerjaan seseorang, dimana tempat bekerjanya, dan bagaimana cara mereka bekerja. Tetapi pada pembelajaran tematik materi pekerjaan SubTema 1 Aku dan Cita-citaku ada keterkaitan antara keduanya. Pada SubTema 1 Aku dan Cita-citaku  membahas tentang impian seseorang yang ingin dicapai karena memiliki minat dan kesukaan yang tinggi atas profesi yang mereka inginkan. Profesi sama saja artinya dengan pekerjaan, oleh karena itu jenis-jenis pekerjaan seseorang dimunculkan pada materi tematik Tema 6. Tetapi, pada materi bahasa Inggris hanya fokus pada jenis pekerjaan seseorang. Kata kunci: Pembelajaran Bahasa Inggris, Kurikulum Tematik, Muatan Lokal
PENERAPAN METODE BERMAIN KARTU SOAL DALAM MENINGKATKAN KEMAMPUAN MENGERJAKAN SOAL CERITA MATEMATIKA BAGI SISWA KELAS VI SDN 4 TUNGGULREJO GABUS GROBOGAN
Authors: Rini Komar Sapto
Published: October 2021

Penelitian ini bertujuan meningkatkan aktivitas belajar dan kemampuan mengerjakan soal cerita mata pelajaran Matematika melalui penerapan metode bermain kartu soal bagi siswa kelas VI SDN 4 Tunggulrejo Kecamatan Gabus Kabupaten Grobogan Semester 2 Tahun Pelajaran 2019/2020. Penelitian dilakukan pada semester 2 tahun pelajaran 2019/2020. Subjek penelitian adalah siswa kelas VI SDN 4 yang berjumlah 17 siswa dengan rincian perempuan sejumlah 9 orang dan 18 orang laki-laki. Penelitian dilaksanakan sebanyak 2 siklus dengan 3 kali pertemuan meliputi: perencanaan, tindakan, observasi dan refleksi. Melalui penerapan metode bermain kartu soal dapat meningkatkan aktivitas beajar dan kemampuan mengerjakan soal cerita mata pelajaran Matematika dengan menggunakan metode bermain kartu soal. Hal ini dapat dilihat dari adanya peningkatan nilai hasil belajar maupun aktivitas belajar tiap siklus. Pada wal nilai rata-rata 66.18 pada siklus I dan menjadi 80.29 pada siklus II dengan ketuntasan 58.82% pada siklus I dan 88.24% pada siklus II. Keaktifan siswa pada siklus I 29.41% aktif dan pada siklus II menjadi 94.12% aktif.
Духовная экономика общества
Authors:   Московский государственный университет им. М.В. Ломоносова, Морозов Владимир Александрович
Published: October 2021

В учебном пособии представлено шесть основных тем с подробным описанием и раскрытием вопросов формирования духовной экономики как условия взаимодействия подсистем общества, субъектов и объектов, организаций-институтов. Определены общие предпосылки совместимости научных школ в области экономики и управления, с выявлением сходств и различий в подходах к изучению и разрешению проблем. Широко и последовательно представлена методологическая основа совместимости систем, включая сферы политики, культуры, научно-познавательной подсистемы общества с их интеграцией в совокупную обновляемую структурную модель общества. Раскрыты теории, концепции и гипотезы развития: общества и человека; совместимости человеческих потребностей и общественных ценностей на платформе динамики ценностей; моральной, нравственной и духовной экономики; совместимости подсистем общества с окружающей средой. По каждой из тем предложена литература. В пособие включен список экзаменационных вопросов и заданий. Содержание работы учитывает профиль экономического факультета МГУ. Для студентов магистратуры, обучающихся по направлениям подготовки «Экономика» и «Менеджмент», изучающих основы формирования социально-экономических систем и их совместной жизнедеятельности.
Investigation of potential rupture locations for abdominal aortic aneurysms with patient-specific computational fluid dynamic analysis approach
Authors: Mutlu Onur , Yalçın Hüseyin Çağatay
Published: October 2021

Background: About 18 million people die each year from cardiovascular disorders, accounting for 31% of all deaths worldwide. Abdominal Aortic Aneurysm (AAA) is a serious clinical condition manifested as dilation of the aorta beyond 50% of the normal vessel diameter. Current clinical practice is to surgically repair large AAAs with a diameter > 5.5 cm. However, the practice is questionable based on small AAA rupture and large AAA no rupture cases. Currently, there is no accepted technique to quantify the risk of rupture for individual AAAs. It is believed that rupture locations are where peak wall stresses act. Hemodynamic forces by the flowing blood such as shear stress are also thought to contribute to the formation of aneurysms leading to rupture. Aim: Our aim is to perform precise computational analysis for the assessment of rupture risk for AAA patients. Methods: In this IRCC funded project, we will develop a patient-specific computational modeling methodology to assess wall stresses acting on the diseased AAA, for reliable rupture risk assessment of the conditions. In the computational simulations, we will adapt the fluid-structure interaction approach to account for both tissue displacements and hemodynamic forces, for enhanced accuracy. We have recruited 20 AAA patients at HMC and collected CT scans and ultrasound images for these patients. Using these medical data, we are developing accurate 3D model geometries. Doppler ultrasound measurements are used as velocity boundary conditions in the simulations. Expected Results: Findings from this project will contribute significantly to understanding the biomechanics and mechanobiology of AAA rupture and will help to establish a computational modeling approach for rupture risk assessment of AAAs.
Genetic Susceptibility to Infectious Diseases in the Qatari Population
Authors: Smatti Maria Khalid , Al-Sarraj Yasser , Albagha Omar , Yassine Hadi
Published: October 2021

Background: Infectious diseases (IDs) account for 8% of deaths annually in Qatar, and therefore, represent a significant challenge for public health. Interestingly, the spread and severity of viral infections vary considerably between individuals and populations. The most recent example is SARS-CoV-2, which ranges from mild/asymptomatic to a severe respiratory syndrome. It has been previously reported that polymorphisms in genes linked to immunity can influence individuals’ responses to infections as observed in tuberculosis, influenza, and HIV; however, studies exploring causal host genetic variants in IDs are still limited and dramatically skewed with regard to population inclusion. In fact, the genetic susceptibility to IDs in the Qatari population is largely unknown. Aim: To perform a comprehensive genetic screening to investigate the presence and frequency of variants previously associated with various infections in the Qatari population. Methods: Whole-genome sequencing was previously performed for 18,000 QBB participants using Illumina HiSeq X Ten1 sequencers. The initial data processing and quality assessment of the raw data has also been performed and variant calling files (VCF) were created. We were granted the access to the VCF files of 6,218 sequenced samples. The genetic variant data was then converted to PLINK file format using PLINK-1.9. Standardized quality-assurance and quality control (QA/QC) methods were followed to generate high quality and confidence on both SNPs and sample levels. The final file used for calculating allele frequency contained 6,047 subjects. Additionally, list of infections-related SNPs that were previously reported in the literature and deposited in GWAS catalog was extracted and used to calculate and compare the allelic frequency in the Qatari genomes compared to other populations. Results: The frequency of infections-related SNPs in the Qatari population was significantly lower for most infections. Most variants (78%) showed negative fold change in the Qatari genomes. Only 22% of all variants were more prevalent in Qatari population compared to others. The most significant differences were observed in genes related to TB and HIV (200-940 and 160-710 fold change, respectively). Conclusion: This study reports a lower susceptibility of the Qatari population to IDs in general. Nonetheless, this might also indicate the presence of unknown Qatari-unique variants and hence, highlights the need for further investigation in future GWAS.
Detection of antinuclear antibodies targeting intracellular signal transduction, metabolism, apoptotic processes and cell death in critical COVID-19 patients
Authors: Fakhroo Aisha , Ali Fatma , Nasrallah Gheyath K. , Marr Nico , Yassine Hadi Mohamad
Published: October 2021

Background: The heterogeneity of COVID-19 lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) has been shown to be the leading cause of mortality in COVID-19 patients, characterized by a hyper cytokine storm. Autoimmunity is proposed to occur as a result of COVID-19, given the high similarity of the immune responses observed in COVID-19 and autoimmune diseases. Results: Here, we investigate the level of autoimmune antibodies in COVID-19 patients with different severities. Initial screening for antinuclear antibodies (ANA) IgG revealed that 1.6% (2/126) and 4% (5/126) of ICU COVID-19 cases developed strong and moderate ANA levels, respectively. However, all the non-ICU cases (n = 273) were ANA negative. The high ANA level was confirmed by immunofluorescence (IFA) and large-scale autoantibody screening by phage immunoprecipitation-sequencing (PhIP-Seq). Indeed, the majority of the samples showed "speckled" ANA pattern by microscopy, and we demonstrate that samples of ICU patients with strong and moderate ANA levels contain autoantibody specificities that predominantly targeted proteins involved in intracellular signal transduction, metabolism, apoptotic processes, and cell death; further denoting reactivity to nuclear and cytoplasmic antigens. Conclusion:Our results further support the notion of routine screening for autoimmune responses in COVID-19 patients, which might help improve disease prognosis and patient management. Further, results provide compelling evidence that ANA-positive individuals should be excluded from being donors for convalescent plasma therapy in the context of Covid-19.
Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging mice
Authors: Cugno Chiara , Halade Ganesh , Mizanur Rahman Md
Published: October 2021

Rosiglitazone is an effective insulin-sensitizer, however, associated with bone loss mainly due to increased bone resorption, and bone marrow adiposity, and decreased bone formation. We investigated the effect of the co-administration of fish oil (FO) rich in omega-3 fatty acids (FAs) on rosiglitazone (RSG)-induced bone loss in aging C57BL/6 mice and the mechanisms underlying potential preventive effect. Mice fed the iso-caloric diet supplemented with fish oil exhibited significantly higher levels of bone density in different regions compared to the other groups. In the same cohort of mice, reduced activity of COX-2, enhanced activity of alkaline phosphatase, lower levels of cathepsin k, PPAR-γ, and pro-inflammatory cytokines, and a higher level of anti-inflammatory cytokines were observed. Moreover, fish oil restored rosiglitazone-induced down-regulation of osteoblast differentiation and up-regulation of adipocyte differentiation in C3H10T1/2 cells and inhibited the up-regulation of osteoclast differentiation of RANKL-treated RAW264.7 cells. We finally tested our hypothesis on human Mesenchymal Stromal Cells (MSCs) differentiated to osteocytes and adipocytes confirming the beneficial effect of docosahexaenoic acid (DHA) omega-3 FA during treatment with rosiglitazone, through the down-regulation of adipogenic genes, such as adipsin and FABP4 along the PPARg/FABP4 axis, and reducing the capability of osteocytes to switch toward adipogenesis. Our findings demonstrate that fish oil may prevent rosiglitazone-induced bone loss by inhibiting inflammation, osteoclastogenesis, and adipogenesis and by enhancing osteogenesis in the bone microenvironment. Further clinical studies will be undertaken to establish this treatment regimen for the successful treatment of diabetic patients with rosiglitazone without adverse side effects on bone.
Pemberdayaan Masyarakat Melalui Pengolahan Keripik Jagung (Zea Mays L.) dengan Bebrbagai Varian Rasa di Desa Babussalam, Kecamatan Gerung, Kabupaten Lombok Barat
Authors: Doyan Aris , Garnasih Inggit , Garnasih Inggit , Algifaari M. Agung , Alam Resda Brahma , Hotimah Husnul , Apriana Nunung Brahma , Permatasari Winda , Irmawati Irmawati , Ariadi Ariadi , Pratiwi Annisa
Published: October 2021

Jagung (Zea mays L.) merupakan komoditas pertanian yang memiliki sekitar 50.000 varietas, salah satunya yaitu jagung manis (Zea mays saccharata) sangat digemari terutama oleh penduduk perkotaan karena memiliki cita rasa yang lezat. Desa Babussalam memiliki Sumber Daya Alam (SDA) yang sangat melimpah. SDA tertinggi yang dimiliki desa Babussalam yaitu tanaman jagung.  Desa Babussalam juga kaya akan Sumber Daya Manusia (SDM). Hal ini dapat dibuktikan dengan luas permukiman seluas 14,918 ha/m2 dengan jumlah penduduk sebanyak 9.278 jiwa. Kendala yang terlihat di desa ini adalah kurangnya kesadaran masyarakat tentang pengolahan bahan mentah menjadi produk jadi yang memiliki nilai ekonomi yang tinggi. Alternatif yang dapat dilakukan untuk mengatasi kendala tersebut adalah “Pembedayaan Masyarakat Melalui Pengolahan Keripik Jagung (Zea mays L.) dengan Berbagai Varian Rasa di Desa Babussalam, Kecamatan Gerung, Kabupaten Lombok Barat.” Tujuan dari program ini adalah untuk membantu menangani pengolahan produksi jagung yang tinggi di desa Babussalam agar memiliki nilai ekonomi yang tinggi. Metode yang digunakan adalah sosialisasi, pelatihan, dan pemasaran produk. Hasil yang didapatkan dari program ini adalah dapat mengubah pola pikir masyarakat dari penjualan bahan mentah menjadi pengolahan bahan mentah menjadi produk olahan. Hal ini tentunya memiliki dampak baik masyarakat sekitar dan perekonomiannya
Diseminasi Perbandingan Produksi Rumput Laut Menggunakan Teknologi Metode Rakit dan Long line di Teluk Ekas Lombok Timur
Authors: Sunarpi Sunarpi , Prasedya Eka S. , Jupri Ahmad , Sunarwidhi Anggit L. , Hernawan Ari , Ilhami Bq T. Khairina , Abidin Angga S. , Widyastuti Sri
Published: October 2021

Rumput laut yang dikenal dengan nama ilmiah makroalga merupakan salah satu komoditi bernilai ekonomi tinggi karena kandungan senyawa hidrokoloid seperti karaginan dan agar. Rendahnya kadar senyawa hidrokoloid yang dihasilkan rumput laut menyebabkan rendahnya harga jual komoditi tersebut. Sistim teknologi budidaya yang digunakan menentukan kualitas rumput laut yang dihasilkan. Artikel ini melaporkan diseminasi teknologi budidaya Eucheuma cottonii dan Eucheuma striatum sistim rakit apung dan long line kepada pembudidaya rumput laut di Teluk Ekas Lombok Timur untuk memacu peningkatan hasil rumput laut baik secara kuantitas maupun kualitas. Diseminasi teknologi dengan dua metode tanam, rakit apung dan long line, dilakukan bersama pembudidaya rumput laut di Teluk Ekas. Diseminasi teknologi yang dibarengi dengan praktek langsung, dapat melihat langsung hasil yang diperoleh dengan penerapan telnologi tersebut, yang pada akhirnya pembudidaya rumput laut mudah memahami dan secara sadar dapat meniru teknologi budidaya tersebut pada musim tanam berikutnya. Dengan demikian, diseminasi teknologi tersebut dapat meningkatkan mutu hasil, harga jual, yang pada akhirnya meningkatkan pendapatan pembudidaya