bluuebunny/crossref_metadata_2025 huggingface dataset:
diseño y experimentación textil como representación y resignificación de la mujer en el postconflicto en Colombia
Authors: Martínez Vanessa , Dotor Ángela
Published: July 2021

Tras la firma de los Acuerdos de Paz, la resocialización de excombatientes y víctimas de la guerra es uno de los principales retos del postconflicto en Colombia, y en él se abordan diferentes componentes que comprenden una reincorporación integral en la sociedad.
En este contexto, este artículo se presenta como reflexión sobre el proyecto de investigación-creación en diseño llamado “Mi historia aún no termina”, planteado como una plataforma de reincorporación social y resignificación de la mujer a través de talleres y laboratorios vivos de diseño con reflexión sobre textil, bordado y tejido, bajo principios de colaboración y cocreación.
El proyecto fue implementado en 2018 en Bogotá–Colombia como una perspectiva de diseño con enfoque social, que se desarrolló a través de un taller de creación que partió de la conceptualización testimonial de la violencia, el cuerpo, la verdad y su valor simbólico para la resignificación de los sujetos, lo que se tradujo en talleres de diseño para la higiene social y la construcción de tejido social. Como resultado de la experiencia se obtuvo una colección de indumentaria (como representación de las mujeres participantes), una exposición de la exploración arte-tejido, y un grupo de mujeres empoderadas en su tejido social.
telar en Cucunubá, tradición que aún se teje a través del diseño contemporáneo
Authors: Alfonso Yanira
Published: July 2021

Esta investigación se centra en la identificación y la transformación del diseño desde la técnica de telar horizontal, usada por los artesanos del municipio de Cucunubá, en el desarrollo de productos textiles, a partir del contacto con entidades académicas de formación en diseño de vestuario y accesorios. Entre estas entidades se encuentran instituciones académicas, fundaciones y organizaciones gubernamentales que no solo representan el estado del diseño contemporáneo en Colombia, sino que también promueven la artesanía en el país.

La investigación se desarrolló con artesanos del municipio de Cucunubá, ubicado en Cundinamarca, Colombia; este municipio se encuentra localizado a 90 km de Bogotá y es reconocido por su larga tradición textil en lana. El diseño metodológico de la investigación tiene un enfoque inductivo, mediante el cual fue posible analizar las particularidades de la técnica empleada por la comunidad. Además, se analizó la coyuntura actual entre la técnica artesanal y el diseño contemporáneo desde la academia y demás entidades gubernamentales e independientes, con las cuales los artesanos han trabajado en los últimos años. Asimismo, se pudo identificar un cambio importante en los procesos de producción, a partir de la modificación de algunas estructuras del telar, las cuales permitieron reducir tiempos de elaboración del producto. También se consideraron etapas importantes como el merchandising, los acabados de los productos y la implementación de puntadas y tejidos en el diseño de las prendas más características.
Repensando un nuevo modelo ciudad post-COVID-19
Authors: Rodríguez José Gesto
Published: July 2021

En la actualidad, muchos investigadores están enfocados en la exploración de la dinámica de la pandemia en las áreas urbanas para la comprensión de sus impactos en las ciudades. Ciertamente, esta crisis sanitaria ha dejado una huella indeleble en la cotidianidad de los grandes asentamientos humanos, obligando a repensar el desarrollo de los mismos en diferentes dimensiones. Particularmente, la disciplina urbanística tiene el reto de generar novedosos modelos que logren mantener el equilibrio entre el nuevo concepto de distanciamiento social y las propuestas que combinen el esfuerzo creativo, así como el adecuado uso de los recursos disponibles en la lucha contra el COVID-19 y otras afectaciones futuras. A continuación se hace un análisis de literatura científica reciente; mediante la revisión de referenciales teóricos que muestran cómo las ciudades pueden repensar sus políticas urbanas para fortalecer su preparación ante riesgos y su capacidad de respuesta, y volverse más resilientes, inteligentes, sostenibles e inclusivas.
Politische Bildung in der Migrationsgesellschaft – demokratische Paradoxien und rassismuskritische Perspektiven
Authors: Füllekruss David , Mecheril Paul
Published: July 2021

Gegenwärtige Demokratien sind in ihrer nationalstaatlichen Verfasstheit von einem Spannungsverhältnis zwischen dem Versprechen von Gleichheit und Gerechtigkeit und der empirischen Realität von Ein- und Ausschlusspraktiken entlang nationalstaatlich kodierter Zugehörigkeiten gekennzeichnet. Insbesondere durch zunehmende Migrationsbewegungen wird dieses normative Paradox des Demokratischen virulent. In diesem Beitrag wird dieses Spannungsverhältnis aus einer rassismuskritischen Perspektive beleuchtet und danach gefragt, inwiefern gegenwärtige und historisch gewordene Demokratien von Rassekonstruktionen vermittelt sind. Daran anknüpfend werden macht- und selbstreflexive Betrachtungsperspektiven einer (rassismus-)kritischen politischen Bildung skizziert.
L’école face aux nouvelles mobilités
Authors: Sanchez-Mazas Margarita , Mottet Geneviève
Published: July 2021

Les écoles accueillent aujourd’hui des élèves issu·e·s de nouvelles migrations, plus mobiles et instables, qui questionnent le modèle de l’intégration scolaire. La méconnaissance des trajectoires de ces enfants, à la scolarité chaotique ou absente, et les déplacements incessants, ne permettent pas aux enseignant·e·s d’inscrire leur pratique dans la continuité. Cet article présente un travail d’enquête comprenant des évaluations en langue d’origine des compétences et besoins d’enfants de requérant·e·s d’asile et documente différents aspects de leur expérience. La question d’équiper les enseignant·e·s et d’ouvrir les écoles à la scolarisation d’élèves migrant·e·s issu·e·s des « nouvelles mobilités » sera discutée à la lumière de l’approche de la reconnaissance.
Morel, S. (dir) (2020). L’épreuve de l’autre : Collaborations, cohabitations et disputes interprofessionnelles en éducation. Academia. 212 pages.
Authors: Progin Laetitia
Published: July 2021

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Sprachsensibel unterrichten – in allen Fächern und für alle Lernenden
Authors: Becker-Mrotzek Michael , Höfler Martha , Wörfel Till
Published: July 2021

Die kognitiven und sprachlichen Voraussetzungen der Schülerinnen und Schüler einer Lerngruppe unterscheiden sich bisweilen deutlich. Dies stellt die Lehrkräfte vor erhebliche Herausforderungen. In der Bewältigung dieser Heterogenität kommt dem sprachsensiblen Unterricht eine herausragende Rolle zu. Der Beitrag diskutiert das bis heute noch vage Konstrukt des sprachsensiblen Fachunterrichts in Hinblick auf seine theoretische und empirische Begründung und skizziert abschliessend einige praktische Schlussfolgerungen.
International human rights protection and promotion in the Organization of Islamic Cooperation: modern trend
Authors: Ivanov D. V. , Pchelintseva V. P.
Published: July 2021

Introduction. The article is concerned with international protection and promotion of human rights by the OIC. Recent developments in the international activity of the organization serve as the thematic justification of the study in the first place, as they reveal certain modifications in its approach to human rights. The study covers several theoretical and practical problems of international public law and national legal orders.

Materials and Methods. Methodology of the study includes general scientific methods, such as scientific assessment and description, scientific analysis and synthesis, abstraction, scientific explanation etc., and special methods of jurisprudence, such as historical, comparative and dogmatic methods. For the purposes of the study, universal agreements and soft law acts as well as OIC acts on human rights were studied alongside with UN databases and scientific and analytical papers on Islamic law and international public law.

Results. The study revealed that activity of the OIC and its member states in the field of protection and promotion of human rights shows more compliance with the universal standards and is likely to continue in that direction. It outlines the pluralistic approach of the OIC to human rights teachings and its concurrent commitment to Islamic and universal human rights concepts. Modifications in the OIC protection of human rights of vulnerable social groups are explored.

Discussion and conclusion. Activity of the OIC in the field of international human rights protection is analyzed from the standpoint of cultural relativism, the views on possible achievement of compatibility of human rights in Islam and universal standards are supported, the approach of the OIC to human rights is considered to reflect the particularities of approaches to human rights of Islamic states and international public law. At the same time ineffectiveness of certain human rights protection measures taken by some mechanisms of protection of human rights of the OIC are pointed out.
Territorial disputes in the North Caucasus as a source of regional instability
Authors: Litvinova T. N.
Published: July 2021

Introduction. The article is devoted to territorial interethnic disputes in the North Caucasus of the Russian Federation, both “frozen” and ongoing, and their impact on regional political processes.

Materials and methods. The theoretical and methodological foundations of the study are the concept of ethnic boundaries and social distance by F. Barth, the works on ethnopolitical conflicts by D. Horowitz, M. Toft, as well as the research of Russian scientists, such as A.V. Avksentiev, D.A. Dmitriev and others. For the North Caucasus, the issue of land ownership, the historical territory of the people has always been painful, it has been the main reason for and factor of interethnic distancing. This research is based on: 1) analysis of official documents of federal and regional authorities; 2) studying declarations of ethic movements and interviews of politicians; 3) media monitoring; 4) classification and situational analysis.

Results. The considered territorial disputes in the North Caucasus can be classified in terms of the  factors underlying the conflicts: territorial disputes as consequences of deportation (North Ossetia and Ingushetia, Dagestan); the problem of divided peoples (Lezgins); disputes over unsettled land ownership (Kabardino-Balkaria, Karachay-Cherkessia and Dagestan); disputes over administrative boundaries (Chechnya and Ingushetia, Chechnya and Dagestan).

Discussion and conclusion. Taking into account the fact of significance of the “historical territory” for the North Caucasian peoples, the resolution of territorial disputes should be carried out with respect for historical memory, with the involvement of conciliation procedures that have strong traditional foundations in North Caucasian societies. Territorial conflicts and grievances lead to mobilization of the people, the growth of protest moods and regional political instability, therefore land issues should be resolved with the involvement of the public opinion. This will help to avoid clashes on an ethno-territorial basis and increase the trust in the authorities.
Modern system of sources of financial law in Russia
Authors: Eremin S. G.
Published: July 2021

Introduction: the article deals with the modern system of sources of financial law in Russia. This article proves that the system of sources of financial law is a complex, multi-level, hierarchical and dynamic formation characterized by a variety and specific diversity of elements, which is not arbitrary or random.

Materials and methods. The methodological basis for this research is a set of methods of scientific knowledge: the analytical method, the method of synthesis and generalization of information. The study of this problem is based on the use of various methods of general scientific and special legal nature: dogmatic analysis, interpretation of legal norms, detailed study of the features of financial and legal documents, logical method, etc.

Results. The analysis showed that the development of sources of financial law in Russia at the present stage is characterized by the presence of a three-level system: federal, regional and municipal levels, and the hierarchical sequence and their interaction is determined by the Constitution of the Russian Federation. The system of sources of financial law in Russia consists of: The Constitution of the Russian Federation, international treaties and international legal norms, federal constitutional laws, federal laws, decrees of the President of the Russian Federation, orders of the Government of the Russian Federation, laws of the entities of the Russian Federation, decisions of local self-government bodies and other normative legal acts.

Discussion and conclusion. As a result of the conducted research, it can be concluded that in order to systematize and logically complete the organization of the modern system of sources of financial law in Russia, it is necessary to adopt a single codified act regulating financial relations at various levels of the legal hierarchy.
Scleral Contact Lenses for Treatment of Ocular Surface Disorders: A Narrative Review
Authors:   Dr. Rajendra Prasad Centre For Ophthalmic Sciences, All India Institute Of Medical Sciences (AIIMS), Ansari Nagar, New Delhi-110029, India, Sah Ramkishor
Published: July 2021

Scleral lenses have been in the origin of contact lenses back in 1880, when the pioneers did the first glass contact lenses. With the advent of highly oxygen permeable materials and the increasing need for advanced solutions for severe ocular surface disorders has produced the driving pressures for a great amount of different contact lens designs to be available.
Parycalcitol + J131 - A New Route to Treatment Secondary Hyperparathyroidism in Patients with Chronic Kidney Disease on Long-term Dialysis?
Authors:   Centre for Nephrological Transplantation Regional Hospital in Szczecin, Szczecin, Poland, Drozd Radosław
Published: July 2021

Two cases with the dramatic course of secondary hyperparathyroidism in patients with chronic kidney disease on long-term dialysis. Has anything possible been done in management of these patients? Complications associated with impaired bone mineralization among patients with chronic kidney disease on long-term dialysis are observed frequently with an array of pathologic processes being found. Kidney osteodystrophy may be associated with either increased or decreased (adynamic bone disease, osteomalacia, aluminum-induced osteopenia) bone metabolism, as well as mixed forms related to the B2 microglobulin amyloidosis. Differential diagnosis of various types of osteopathy is difficult and is usually based on the histologic assessment of the bone biopsy. The most typical bone complication in patients with impaired kidney function is osetodistophy with increased bone metabolism, caused by secondary hyperparathyroidism clinically manifesting as osteitis fibrosa. High serum levels of PTH induce osteoclast and osteoblast activity. Early changes, with characteristic increase in the woven osteoid suggesting early, increased osteoplastic bone resorption may be found in a significant percentage of patients with GFR>60ml/min/1,73m2 of the body surface. Lower values of the GFR are associated with both faster bone synthesis and more active resorption with progressive increase in the intraosseous fibrosis and decreased bone mineralization. As the abnormalities progress, which is especially marked in patients on long-term dialysis, a rage of clinical symptoms, such as: severe bone and joint pain, bone deformation, pathological fractures, especially in the spinal region, calcifications of the soft tissues and vessels, including heart valves and lungs. In children, the most common abnormality is growth impairment. In some patient’s skin calcifications, with subsequent necrosis, due to increased calcium deposition in small and medium arteries. The diagnosis is based on the typical clinical picture, biochemical parameters (calcium and phosphate ratio, parathormone levels, characteristic radiologic charges and sometimes, bone histology. Prevention and treatment of these complications includes effective dialysis, appropriate low-phosphate diet with limitation of the protein supply to the 0.8g/kg of the body mass, adequate calcium and active Vitamin D3 supply, introduction of the phosphate binding medications (sevelamer or lantan) as well as calcimimetic use (substances activating parathyroid gland calcium receptors inhibiting both its up-regulation and PTH secretion). In the severe cases, with insufficient effect of the treatment described above, parathyroidectomy is required after close ultrasound and scintigraphy-based assessment of these glands. However, even such treatment may be insufficient in some cases, as presented below.
investigación como herramienta en la formación de recursos humanos, un punto de vista desde la Universidad Veracruzana
Authors: Trigos Ángel
Published: July 2021

Tengo que reconocer que, a pesar de haber iniciado mi carrera como docente hace más de 40 años, no me considero un experto en educación, por lo que escribir el editorial en una revista especializada y con amplio reconocimiento en América Latina en esta área, solo me queda agradecer la deferencia hacia mi persona y me llena de placer compartir un punto de vista personal que espero sirva para reflexionar sobre la importancia de hacer investigación como una herramienta para la generación de recursos humanos especializados, así como un breve análisis del potencial en investigación de la Universidad Veracruzana.
Creación y acreditación de posgrados a distancia en dos universidades mexicanas
Authors: Cabrera Hernández Dulce María
Published: July 2021

El objetivo del artículo es describir las estrategias orientadas a la creación y la acreditación de posgrados a distancia en dos universidades mexicanas. La investigación fue cualitativa, adoptamos el método narrativo-biográfico con dos técnicas de acopio de información: grupos focales y entrevistas a estudiantes, académicos y coordinadores en la Universidad de Guadalajara y la Autónoma de Querétaro. Los resultados indican que las dos comunidades académicas desarrollaron tres estrategias de creación: virtualización de programas presenciales, impulso de proyectos institucionales y diseño de nuevos posgrados. Además, operaron dos estrategias de adaptabilidad: organización de modelos educativos propios y producción de conocimientos situados para responder a la acreditación. Las conclusiones señalan que los miembros de las comunidades académicas establecen compromisos personales y colectivos con sus universidades, sortean dinámicas de evaluación, y potencian las condiciones institucionales para acreditarse en el Programa Nacional de Posgrados de Calidad del Consejo Nacional de Ciencia y Tecnología.
Essential oil composition of Origanum vulgare and its application in substitution of synthetic chemical additives
Authors: Heni Sonia , Boughendjioua Hicham , Bennadja Salima , Djahoudi Abdelghani
Published: July 2021

In this work, the gas  chromatography-mass spectrometry (GC/MS) analysis of the essential oil of Origanum vulgare. L. obtained by hydrodistylation was warried out and it allowed to identify 98.1% of its constituents. The main components are carvacrol (47.6%), thymol (16.6%), p-cymene (13.5%) andγ-terpinene (11.2%). The chemical components of the essence are distributed over five biochemical classes represented mainly by monoterpene phenols and monoterpene carbides. The extraction gave a yield of oil 2.8%. The minimum inhibitory concentration (MIC) of this oil was determined against food spoilage bacteria and pathogenic bacteria belonging to the genus Staphylococcus tested in vitro. This study aims to enhance the value of oregano essential oil by determining its chemical composition on the one hand, and by its application as a natural antibacterial preservative in substitution of synthetic chemical additives on the other hand. The sample was incorporated into a sensitive food matrix exposed to bacterial contamination: white meat. The bacteriostatic/bactericidal power of this bioactive extract was determined by a significant reduction in the number of bacteria and a clear increase in shelf life. Thus, it is possible to propose the use of this aromatic essence as a source of natural preservative.
The efficacy ofHamamelis30 in the management of varicose veins and its complications using revised venous clinical severity score tool and peripheral venous Doppler study
Authors: Lobo Blany John
Published: July 2021

Objectives:

The homoeopathic remedy,Hamamelis, has been extensively used to treat varicose veins. However, scientific research conclusively proving its utility is lacking. This study was performed to ascertain the remedy’s therapeutic utility and efficacy in treating varicose veins and its complications using the revised venous clinical severity score (VCSS) tool and Doppler studies.

Materials and Methods:

A prospective uncontrolled experimental study with purposive sampling was performed; the subjects were selected from the outpatient department. A total of 32 cases, fulfilling the inclusion and exclusion criteria were clinically examined. The VCSS and Doppler test before and after treatment withHamamelis30 were performed.

Results:

The Wilcoxon signed-rank test was applied and the change in the median VCSS was found to be statistically significant.P-value of the pre score was 5.53 ± 4.15 and that of the post score was 3.45 ± 2.36 with a mean change of 2.09 ± 2.87 and 37.69% improvement withP-value of 0.000 < 0.01. The Doppler study showed no significant change or improvement.

Conclusion:

This study revealed that the homoeopathic remedyHamamelis30 is effective in the management of varicose veins and its complications by ameliorating symptoms and improving the VCSS. However, the Doppler study reports showed no changes or improvement perhaps due to the short period of treatment.
A brief review onNux vomica: A panacea homoeopathic remedy
Authors: Rehman Tayyeba
Published: July 2021

Strychnos nux-vomicais a homoeopathic remedy that has long been considered a panacea. This review collected the clinical trials and/or experimental studies on the pharmacological effects ofNux vomica. An electronic database search was run on Google Scholar and PubMed from 1980 to 2018. Data from homoeopathic texts available on paper and electronically were also included. Conventionally,Nux vomicais a medicine for alcoholism, anger effects of, colic, constipation, dyspepsia, gastrodynia, haemorrhoids, tea and tobacco habit, insomnia, nightmares, lumbago and many more diseases. Various pharmacological studies have proved its anti-alcoholic effect. Studies also showed its effect on sleep quality, anxiety-related behavioural patterns and epilepsy survival time. It also inhibitedHelicobacter pylori-induced gene expression.Nux vomicawas found to be beneficial in treating baker’s yeast-induced acute high-grade fever, pock-like lesions and Reiter’s disease. However, further research studies are required to explore its traditional uses for other diseases.
Skin erosion in deep brain stimulation procedures: Using the temporalis muscle to treat this complication – A technical note
Authors: Britz João Pedro Einsfeld , Franceschini Paulo Roberto , Ramos Miguel Bertelli , de Aguiar Pedro Henrique Pires , Farah Jibril Osman , de Aguiar Paulo Henrique Pires
Published: July 2021

Background:

Skin erosion is a common complication after deep brain stimulator procedures. Despite being a relatively common event, there is no standard surgical technique or a widely accepted guideline for managing this kind of complication.

Methods:

We describe a case of cutaneous erosion in the connector’s site of deep brain stimulation case, surgically managed with anterior displacement of the connectors and overlapping and wrapping the connections within the temporal muscle.

Results:

Postoperatively, the patient did well and achieved complete resolution of the skin erosion, with no signs of infection or new skin lesions.

Conclusion:

This technique demonstrated to be effective in this case in the long-term follow-up.
Delayed asymptomatic retroperitoneal dislodgement into the pouch of Douglas of a TLIF cage: A case report and review of the literature
Authors: Kumar Manoj , Kaucha Deepak , Adsul Nitin , Chahal R. S. , Kalra K. L. , Acharya Shankar
Published: July 2021

Background:

Intraoperative anteropulsion of a transforaminal lumbar interbody fusion (TLIF) cage is infrequent but may have disastrous complications. Here, we present an 80-year-old female whose L5-S1 TLIF cage extruded anteriorly and later migrated into the pouch of Douglas (i.e. an anterior peritoneal reflection between the uterus and the rectum) posing potential significant risks/complications, particularly of a major vessel injury. Notably, this 80-year-old patient with degenerative lumbosacral scoliosis should have only undergone a lumbar decompression alone.

Case Description:

An 80-year-old female underwent a two-level L4-L5 and L5-S1 TLIF to address lumbosacral canal stenosis with degenerative scoliosis. During the L5-S1 TLIF, intraoperative fluoroscopy showed the anterior displacement of the cage ventral to the sacrum. As she remained hemodynamically stable, the cage was left in place. The postoperative CT scan confirmed that the cage was located in the retroperitoneum but did not jeopardize the major vascular structures. Three months later, however, the cage migrated inferiorly into the pouch of Douglas. Although asymptomatic, general surgery and gynecology advised laparoscopic removal of the cage to avoid the potential for a major vessel/bowel perforation. However, the patient refused further surgery, and 3 years later remained asymptomatic.

Conclusion:

Anterior cage migration following TLIF has been rarely reported. In this case, an L5-S1 TLIF cage extruded anteriorly in an 80-year-old severely osteoporotic female and migrated 3 months later into the pouch of Douglas, posing the risk of a major vessel/bowel injury. Although surgical removal was recommended, the patient refused further surgery but remained asymptomatic 3 years later. Notably, the authors, in retrospect, recognized that choosing to perform a 2-level TLIF in an 80-year-old female reflected poor judgment.
Recurrent adult pilocytic astrocytoma presenting with intraventricular and leptomeningeal spread
Authors: Khan Khadeja , Luther Evan , Morrell Alexis A. , Tan Sze Kiat , Eichberg Daniel G. , Shah Ashish H. , Lu Victor M. , Gultekin Sakir H. , Morcos Jacques J.
Published: July 2021

Background:

Infratentorial pilocytic astrocytomas are uncommon tumors in adulthood but are thought to be prognostically similar to their pediatric counterparts with excellent overall survival following gross total resection. However, given the relative rarity of these tumors, no management guidelines exist for recurrent adult pilocytic astrocytomas (APAs). This lack of consensus is especially problematic for inoperable recurrences or those with aggressive features concerning for malignant transformation.

Case Description:

In 2017, a 26-year-old female presented with headaches, nausea, vomiting, and blurry vision. A brain magnetic resonance imaging (MRI) demonstrated a large, well-circumscribed mass within the fourth ventricle causing obstructive hydrocephalus. She underwent near-total resection through a midline suboccipital transtonsillar approach. Pathology demonstrated a World Health Organization Grade 1 pilocytic astrocytoma. Despite initial improvement in her symptoms, she developed worsening headaches and lethargy 10 months after surgery and repeat MRI demonstrated recurrent tumor within the entire ventricular system and the subarachnoid spaces of the left cerebellopontine angle suggesting leptomeningeal spread. Due to the unresectable nature of the recurrence, the patient declined any further intervention and succumbed to her disease 6 months later.

Conclusion:

We present the first case of a recurrent APA presenting with intraventricular and leptomeningeal spread. Although thought to be a benign neoplasm, close interval follow-up with serial imaging is of essential, especially in those patients with known residual tumor, to prevent aggressive recurrences such as this.
Assessment of the possibility of using dermal fibroblasts for reconstruction of oral tissue defects
Authors: Lugovets D. V. , Fadeyev F. A. , Sarkisyan N. G. , Melikyan S. G.
Published: July 2021

Relevance of the research topic.The regeneration of oral mucosa occurs without signifcant scarring, in contrast to skin wounds healing. Oral fbroblasts are characterized by the increased ability to replace and remodel the extracellular matrix (ECM) during wound healing, as compared to skin fbroblasts, together with the higher level of secretion of cytokines stimulating cells proliferation. The inﬂammatory reaction in oral mucosa injuries is less intensive than in skin wounds.

Purpose.The goal is to review the literature on the topic to assess the possibility of using dermal fbroblasts for treating oral tissue defects Oral fbroblasts transplantation by injection or on various matrices signifcantly improves the recovery from periodontitis and gingival recession. Besides, positive effects of treatment can be achieved by using tissue substitutes containing autogenic oral fbroblasts and keratinocytes.

Methods and materials.A review of the literature on the topic of 70 sources from them 12 domestic and 58 foreign data. Some researches demonstrate the key role of subepithelial tissue cells in the defnition of the upper epithelium cells properties.

Results.At the same time, there are some reports about successful non-tissue-specifc transplantation, e.g. the treatment of oral mucosal defects by using tissue substitutes containing skin fbroblasts and keratinocytes.

Summary.It is still unclear, whether skin-derived cells are suitable for stimulating the regeneration of oral injuries, further research required.
Features of hard tooth and periodontal tissues among women with diabetes mellitus in various trimesters of pregnancy
Authors: Orekhova L. Yu. , Musaeva R. S. , Silina E. S. , Aleksandrova A. A. , Grinenko E. V. , Loboda E. S.
Published: July 2021

Relevance of the research topic. There is a relationship between dental status of a pregnant woman and time of gestation. It is known that oral condition is changing depending on the trimester of pregnancy.

Purpose. The aim of the research was to study and compare the clinical condition of oral cavity in this group of patients, depending on the gestation period.

Methods and materials. For this purpose 110 pregnant women with diabetes mellitus were examined with using basic and additional examination methods.

Results. Pregnant women in 2 gestation period have the worst condition of oral cavity.

Summary. Analysis of results of the study allows us to determine the most critical phase during pregnancy and in future to promote normalization of oral cavity precisely in this period.
The oral cavity micro-biocenosis in case of desquamative glossitis associated with small intestinal bacterial overgrowth
Authors: Uspenskaya О. А. , Schevchenko Е. А. , Kazarina N. V. , Legostaeva M. V.
Published: July 2021

Relevance of the research topic.Small intestine bacterial overgrowth (SIBO) is one of the major factors in the development and persistence of digestive diseases and associated non-digestive disorders. The human gastrointestinal tract microbiota of different biotypes features a community of microorganisms with complex interrelationships. The mouth is the beginning of the digestive system and most easily accessible organ for specimen collection. Assessment of the oral mucosal surface works as a diagnostic test reﬂecting a somatic pathogenesis at its earliest stages. A hydrogen breath test is a non-invasive diagnostic tool for SIBO. The test entails measuring the hydrogen concentration in the exhaled air which is the metabolite of a quantitatively and qualitatively changed intestinal microﬂora. Small intestinal microbiota imbalance triggers the impairment of other gastrointestinal tract organs. It can cause oral, upper respiratory and gut tract microbial dysbiosis.

Purpose.The main concern of this study is to explore the oral microbiota of patients with desquamative glossitis coupled with SIBO.

Methods and materials.Clinical studies of 36 patients with desquamative glossitis and varying degrees of severity of SIBO generated data for this research. The comparison group comprised 12 persons with desquamative glossitis not paired by SIBO. The generated data was juxtaposed to normal reference values of the oral microbiota biocenosis. SIBO was diagnosed through hydrogen breath monitoring provided by the Gastro+Gastroliyser (BEDFONT) system while oral microﬂora was assessed based on culture tests.

Results.The research showed that patients with more severe SIBO and desquamative glossitis manifest a more apparent oral dysbiosis with a simultaneous decrease of normal bacteria and an increase in the amount of conditionally pathogenic bacteria. However, patients who have desquamative glossitis but do not suffer from SIBO tend to show a stable normal microbial ﬂora and a growth of conditionally pathogenic bacteria.

Summary.The research revealed that the deranged oral microbiota of patients with desquamative glossitis vary in its degree depending on the severity of SIBO as shown by hydrogen breath tests.
Features of morphological changes of peridont tissues in patients with β-thalassemia major
Authors: Shadlinskaya R. V. , Qasimov E. K. , Rzayev F. Q.
Published: July 2021

Relevance of the research topic.Β-thalassemia major is a hereditary blood disease, the functional manifestation of which is the defciency of synthesis of the β hemoglobin chain, leading to the occurrence of severe hypochromic anemia in the frst two years of postnatal development. Treatment of the disease requires a lifelong transfusion, which leads to the iron overload disorder. The development of hemosiderosis contributes to the chronization of inﬂammatory processes and cellular modifcation of organs and tissues, including the oral cavity. Inevitable metabolic disorders that occur during β-thalassemia prevents the full functional participation of macro- and microelements in metabolic processes in the periodontium, which is necessary for collagen modifcation.

Purpose.The aim of the study is to identify the features of morphological changes in the gingival mucous membrane in patients with β-thalassemia major with generalized gingivitis in remission stage in order to determine potential points of application of additional corrective therapy. Materials and methods. The study included 12 patients with β-thalassemia major (the average age of the subjects was 15 ± 0.1 years). Dental examination was carried out in accordance with the recommendations of the WHO, 1990. Araldite-Epon blocks were formed according to the generally accepted method. The production of semi- (1-2 microns) and ultrathin (35-70 nm) sections were obtained using a Leica EM UC7 ultramicrotome (Germany). Semi-thin sections (1-2 μm) were stained by trichrome staining according to F. D'Amico (2005). Viewing of stained and unstainted ultrathin sections was performed on an JEM-1400 electron microscope (Japan) at an accelerating voltage of 80-120 kV.

Results.Periodontal modifcation in the remission stage of catarrhal-sclerosing gingivitis in patients with β – thalassemia major is morphologically marked by disorganization of the connective tissue with destruction of the collagen structures and defciency of the presence of immunocompetent cells in its matrix. Elements of dense connective tissue spread from the papillary part of the lamina propria, where elements of loose connective tissue are usually located. The accumulation of immunocompetent cells in the composition of the connective tissue and in the vascular elements's lumen (both blood and lymphatic) of the lamina propria is not detected.

Summary.An inﬂammatory periodontal disease in patients with β-thalassemia major is characterized by marked disorganization of the connective tissue, which requires therapy aimed to develop a correction of mineral metabolism, antioxidant protection and activate the mechanisms of anti-infective protection of the periodontal tissues.
Evaluating Carotid intima media thickness (CIMT) of patients with Non - Alcoholic fatty liver disease (NAFLD) as a risk factor for atherosclerosis and correlation with metabolic syndrome
Authors: Raghuram K  , Lavanya  , Ram Kumar M  , Jagadeesan M  , Prasanna Karthik S  , Kannan R  , Gowrishankar A  , Mageshkumar S
Published: July 2021

This study aimed to evaluate the effect of NAFLD on CIMT as a risk factor for atherosclerosis. The incidence of non-alcoholic fatty liver disease (NAFLD) is escalating worldwide due to mount of obesity and diabetes mellitus (DM) prevalence. Non-invasive appraisal of carotid intima-media thickness (CIMT) by high-resolution carotid B-mode ultrasonography is broadly used for determining atherosclerosis. In this case-control setting, 151 subjects were categorized in three groups: group I counting 49 patients with NAFLD and DM; group II counting 50 non-diabetic NAFLD patients; and the control with 52 normal subjects as group III. The right and left CIMTs and its maximum reading (CIMT max) were deliberated by a skilled sonographist blind to the groups. The sonographic grading of the NAFLD was dogged in groups I and II. Median CIMT max was extensively higher in group I comparing with group II and control group (p<0.001). This disparity between group I and group II were not significant after adjusting for age and history of hypertension and hyperlipidemia (p=0.089). After scheming the confounders, there was a statistically significant between-group I and group II with the control group (p<0.05). There was no significant disparity in median maximal thickness of intima-media in the carotid of group I compare to group II in patients with and without prominent liver enzymes (in both groups, 0.6 mm, p= 0.402). Based on our findings, there is a significant relationship between the presence of NAFLD and atherosclerosis. This association was independent to the Diabetes mellitus presence. The grade of NAFLD and elevated liver function tests had no effect on the severity of atherosclerosis.
AN APPROACH TO ASSESSING THE PARAMETERS OF THE REGIONAL ATTRACTIVENESS OF THE REGION'S ECONOMY FOR INTERNATIONAL LABOR MIGRANTS
Authors: Гризовская Дарья Викторовна
Published: July 2021

Для современного этапа экономического развития характерно наличие в региональной экономике изменения соотношения числа международных трудовых мигрантов и числа эмигрантов, что выражается, с одной стороны, в потере значительной части трудоспособного и высококвалифицированного населения, а с другой, - в увеличении доли низкоквалифицированного труда из-за международной трудовой миграции. Целью исследования является разработка регрессионной модели оценивания миграционной привлекательности региона по многомерным данным, представляющим макроэкономические показатели. Методологической основой исследования является комплексный подход, в рамках которого понятие «миграция» рассматривается в качестве объективного фактора, обеспечивающего развитие экономики региона и представляющего собой целеориентированный процесс, заключающийся во въезде в страну международных трудовых мигрантов. Это, с одной стороны, предоставляет возможности развития региональной экономики, а с другой, - усиливает риски экономического развития региона. Научная новизна исследования представлена разработкой подхода к оценке количественных и качественных параметров привлекательности экономики региона для международных трудовых мигрантов с учетом приоритетов и направлений развития региональной экономики.

The current stage of economic development is characterized by the presence in the regional economy of a change in the ratio of the number of international labor migrants to the number of emigrants, which is expressed, on the one hand, in the loss of a significant part of the able-bodied and highly skilled population, and on the other, in the increase in the share of low-skilled labor due to international labor migration. The aim of the study is to develop a regression model for assessing the migration attractiveness of the region from multivariate data representing macroeconomic indicators. The methodological basis of the study is an integrated approach, in which the concept of "migration" is considered as an objective factor that ensures the development of the region's economy and is a targeted process consisting in the entry of international labor migrants into the country. This, on the one hand, provides opportunities for the development of the regional economy, and on the other, increases the risks of the economic development of the region. The scientific novelty of the study is represented by the development of an approach to assessing the quantitative and qualitative parameters of the attractiveness of the region's economy for international labor migrants, taking into account the priorities and directions of the development of the regional economy.
DEVELOPMENT OF ECONOMIC FUNCTIONS OF THE STATE IN THE CONTEXT OF DIGITALIZATION
Authors: Руденко Ирина Владимировна
Published: July 2021

Цель статьи: обоснование необходимости корректировки функций государства и механизма их осуществления в зависимости от функционирования хозяйственной системы в условиях цифровой трансформации. Научная новизна: реализация экономических функций государства с помощью цифровых технологий рассматривается на основе холистического подхода через взаимодействие частных и общественных интересов в процессе совместного принятия решений. По результатам проведенного исследования сделан вывод о том, что использование современных инструментов реализации государственного администрирования, таких как, цифровые платформы, краудсорсинг, приводит к взаимодействию интересов всех субъектов современного общества, что способствует качественным изменениям в развитии экономических функций государства в условиях цифровизации.

The purpose of the article is to justify the need to adjust the functions of the state and the mechanism for their implementation depending on the functioning of the economic system in the context of digital transformation. Scientific novelty: the realization of the economic functions of the state through digital technologies is considered on the basis of a holistic approach through the interaction of private and public interests in the process of joint decision-making. According to the results of the study, it was concluded that the use of modern tools for the implementation of public administration, such as digital platforms, crowdsourcing, leads to the interaction of the interests of all subjects of modern society, which contributes to qualitative changes in the development of the economic functions of the state in the conditions of digitalization.
THE PROSPECTS OF SMALL BUSINESS DEVELOPMENT IN THE RUSSIAN ECONOMY
Authors: Албендов Рашад Мугабил оглы
Published: July 2021

Цель статьи - рассмотреть динамику развития малого бизнеса в экономике России и наметить вектор его дальнейшего движения. Важность малого бизнеса признана во всем мире, малые предприятия создают рабочие места и обеспечивают существенную долю населения доходами, что позволяет говорить об актуальности рассматриваемой темы. В статье рассматриваются проблемы и сложности развития и расширения малого бизнеса. Элемент научной новизны заключается в выявлении некоторых проблем малого бизнеса на современном этапе.

The purpose of the article is to consider the dynamics of small business development in the Russian economy and outline the vector of its further movement. The importance of small businesses is recognized throughout the world, small enterprises create jobs and provide a significant share of the population with incomes, which allows us to talk about the relevance of the topic. The article discusses the problems and complexities of small business development and expansion. An element of scientific novelty is the identification of some problems of small businesses at the present stage.
COMMERCIALIZATION OF NEW KNOWLEDGE AND THE CONCEPT OF «ACADEMIC CAPITALISM»
Authors: Дадаев Якуб Элхазурович , Закриева Зинаида Магомедовна
Published: July 2021

Статья посвящена рассмотрению особенностей появления и распространения в мире феноменов «академический капитализм», «университетское предпринимательство», нового типа организации деятельности университетов, ориентированных на предпринимательство в сфере образования. Целью статьи является исследование теоретико-методологических основ инновационного развития системы образования на базе анализа феномена университетского (академического) предпринимательства, оценки его роли в инновационном развитии общества и на основе изучения исторических причинно-следственных связей - рассмотрение причин возникновения «академического капитализма» и развития университетского предпринимательства. В статье определено, что «академический капитализм» является интеллектуально-знаниевой предпринимательской составляющей капиталистической экономической системы, которая непосредственно влияет на его подсистемы - производительные силы, технико-экономические и производственные отношения, хозяйственный механизм. Научная новизна полученных результатов заключается в обосновании такого феномена как «академический капитализм», позволяющего эффективное использование его технологии и получение выгоды от академического (университетского) предпринимательства образовательным организациям России для достижения научно-технических, технологических и финансовых успехов.

The article is devoted to the consideration of the peculiarities of the emergence and spread of the phenomena of «academic capitalism», «university entrepreneurship» in the world, a new type of organization of the activities of universities focused on entrepreneurship in the field of education. The purpose of the article is to study the theoretical and methodological foundations of the innovative development of the education system based on the analysis of the phenomenon of university (academic) entrepreneurship, assessment of its role in the innovative development of society and based on the study of historical causal relationships - consideration of the causes of the emergence of «academic capitalism» and the development of university entrepreneurship ... It is determined that «academic capitalism» is the intellectual and knowledge entrepreneurial component of the capitalist economic system, which directly affects its subsystems - productive forces, technical, economic and production relations, economic mechanism. The scientific novelty of the results obtained lies in the justification of such a phenomenon as «academic capitalism», which allows the effective use of its technology and benefits from academic (university) entrepreneurship to educational organizations in Russia to achieve scientific, technical, technological and financial success.
Basics of web design using HTML
Authors: K Rajeshkumar , C Ananth
Published: July 2021

This book entitled “Basics of web design using HTML” has been written based on the ease of learners. The chapters of this book have been discussed in detail.The discussed units will ensure as a companion to understand the subject more easily and clearly with suitable examples. In order to learn effectively, I advise the learners to learn the subject topic wise with note making technique.