bluuebunny/crossref_metadata_2025 huggingface dataset:
Obstetric and Neonatal Outcomes in Congenital Isolated Cardiac Anomalies - Single Center Experience
Authors: Çağlıyan Erkan , Ozmen Samican , Sarıdaş Demir Süreyya , Akdöner Aslı , Altunyurt Sabahattin , Deliloğlu Burak , Yıldız Kaan , Genç Hal,se Seynep , Kır Mustafa
Published: December 2020

INTRODUCTION: Evidence shows that rather than postnatal diagnoses, prenatal diagnoses of congenital heart diseases are correlated with better long-term results and lower mortality rates. In this retrospective study, neonatal stage results of infants with isolated cardiac anomalies, their indications for operation or intervention (if any), and the mortality rates in the first age are attempted to be demonstrated. METHODS: The study was conducted through the retrospective analysis of 47 patients who were diagnosed with fetal cardiac anomaly in the antenatal period, and monitored during natal and postnatal stages at the same center in the Departments of Obstetrics and Gynecology and Pediatric Cardiology of Dokuz Eylul University Hospital. RESULTS: In our center 36 patients gave birth by cesarean section, and 11 patients by spontaneous vaginal delivery. Two low birthweight neonates were born (<2500 g), and these neonates were observed to have hypoplastic left heart and Fallot tetralogy. Thirty-nine of the 47 neonates born with isolated cardiac anomaly were operated after birth. Five patients were advised follow-ups. The remaining 3 neonates died within 48 hours after birth. Survival rate of the operated neonates was 59.5% and the general survival rate was 59.5%. Average 1, and 5-minute APGAR scores of the infants were 7.8 (3-9) and 9.0 (8-10), respectively The neonates were operated an average of 3 days after birth, and the average duration hospitalization of neonates were 12 days. Twenty-nine neonates needed preoperative respiratory support and 37 of them received prostaglandin E1 infusion. Follow-up was advised for 3 neonates within the first month and the first year. Five neonates needed operation during the specified period, and 2 neonates died. DISCUSSION AND CONCLUSION: In conclusion, prenatal diagnosis of congenital heart diseases allows planning the delivery in tertiary care centers, stabilization of the infants in the preoperative period and realization of emergency intervention.
Effect of serve on reception and side-out performance in relation to ball´s contact with the net and type of serve, in high level male volleyball. [Efecto del saque en el rendimiento de la recepción y en el complejo I en función del contacto del balón con la red y el tipo de saque, en voleibol].
Authors: López Eduardo , Díez-Vega Ignacio , Molina Juan José
Published: December 2020

The contact of the serve’s ball with the net in volleyball generates uncertainty in the receivers, due to the change in trajectory and speed that occurs. The objective of this study was to determine the influence of the serve contact with the net on the performance of the receiving team, on male teams of the highest international level. A total of 4,227 actions of reception or side-out corresponding to 29 matches were analysed, of which only 275 contacted the net (5.42%). Reception performance was higher in the power jump serves that contacted with the net (p<0.001). However, the effect of contact with the net on floating serves did not have a significant impact. The final performance of the side-out did not make a significant impact neither. In conclusion, the contact of the ball with the net affects the reception performance in the highest international men's volleyball teams.
Scenario Analysis of the Intellectual Capital Development of the Region in Postcovid Economics Based on Financial Assets
Authors: Ilgizovich Gataullin Iskander , Zabirova L. M.
Published: December 2020

The article presents the main trends and factors involved in developing intellectual capital in the region during and after the pandemic of Covid-19 based on financial assets, which are of strategic importance both for the state and for international development. The authors provide benefits and drawbacks to the growth of the situation in the context of the main elements of the region's intellectual capital. These factors consist of Innovative activities in the region (Intellectual Property Market, Innovative infrastructure of the region, Innovative activities of organizations) and Human Resources (Labor Market, Higher, and Continuing Professional Education System). A pessimistic scenario involves that the state and the economic system could not cope with a negative trend for various reasons. On the other hand, an optimistic scenario implies that the state and economic entities can see the trend as an opportunity and apprehend it to stabilize the region's economic situation and further surmount the crisis.
Financial Statement Fraud Detection With Beneish M-Score and Dechow F-Score Model: An Empirical Analysis of Fraud Pentagon Theory in Indonesia
Authors: Ratmono Dwi , Darsono Darsono , Cahyonowati Nur
Published: December 2020

This research contributes to the Financial Statement Fraud (FSF) literature by examining the ability of the Beneish model and the F-Score model to detect FSF trends in the Indonesian context. This study also aims to provide empirical evidence on other issues that encourage fraud. The results of this study are empirical evidence that the financial target variables and CEO narcissism have a significant effect on financial statement fraud while financial stability, external pressure, supervision ineffectiveness, related party transactions, auditor turnover, and CEO dominance have no significant effect on financial statement fraud. Furthermore, when viewed in the table of the F-Score and M-Score models, there are several companies suspected or indicated of fraudulent financial reporting, including 284 companies out of 385 observation samples. The percentage of companies indicated to have financial statements fraud requires further examination to really prove that the company is cheating. The results of the fraudulent financial report analysis using the F-Score dan M-score for manufacturing companies in 2014 - 2018 successfully analyzed a total of 284 companies that indicated fraudulent financial reporting.
Strategic Management System of the Territory as a Factor of Increasing Its Competitiveness Level in Financial Organizations
Authors: Vorobyev Andrey A. , Glebova Irina S. , Khafizova Liliya V.
Published: December 2020

This paper proposes a methodology for assessing the development level of the strategic management system and the competitiveness level in financial organizations. This methodology served the basis for an analysis of regions and federal cities the Russian Federation. A correlation analysis is also carried out to define the dependence of the constituent entity's competitiveness on the development of the strategic management system that resulted in the proposition of comprehensive solutions.
A Review of Bio-Processing of Market Crop Waste to Poultry Feed in Uganda
Authors: Kisuule Noah , Kiggundu Nicholas , Banadda Noble
Published: December 2020

This paper reviews the current state of bio-processing of market waste to poultry feed in Uganda. A focus was put on crop wastes since previous studies have indicated that, they contribute the biggest percentage (about 90%) of the total organic waste generated in markets. These wastes majorly comprise of fruits and vegetables like mangoes, pineapples, jackfruit, watermelon, cabbage among others. They are usually in form of residual stalks, leaves, peels, and damaged/rotten crops. Crop wastes are rich in various bioactive and nutraceutical compounds, like carotenoids, polyphenols and dietary fiber. The wastes are a major worthwhile raw material and present feasible solutions to the problems of poultry feed scarcity and high costs associated with the conventional feed stuffs. This transformation can be achieved by developing appropriate technologies for valorization of wastes by nutrient enrichment. In concern to this, solid state fermentation (SSF) and rearing insects and earthworm using crop wastes are the promising novel technologies. High value added products/feeds can be produced through microbial fermentation of crop wastes. Insect protein can also be produced to replace the expensive silver fish and soybean protein sources. The review indicated that, the technologies have not been fully cherished within the country’s poultry feed industry. All the attempts and work done are still under research and pilot scale level. However, the on-going endeavors are continued widely to better conversion technologies in order to produce products that are safe for poultry feeding. Lastly, the limitations and strategies for processing poultry feed from market waste are reviewed.
Verso la filosofia: Nuove prospettive su Parmenide, Zenone e Melisso
Authors: Rossetti et al. Livio
Published: December 2020

Like in the previous volumes of the series, the book encompasses two parts: Firstly, the main author Livio Rossetti gives three lectures on the Eleatics, aiming to open up new perspectives on them. For instance, he delves into Zeno’s paradoxes – not to attempt to resolve them as has been attempted too many times, but to find how Zeno mounted them and captured his audience. Furthermore, Rossetti raises the point of ‚virtual philosophy‘ concerning the Eleatics, as those who are not aware of being philosophers, like Confucius, or Thales and Heraclitus.

The second part of this book hosts some vivid exchanges between its main author and several scholars, among them Nestor Cordero, A.P.D. Mourelatos, Jaap Mansfeld, Rose Cherubin and Vincenzo Fano.
Zwischen Geist und Macht
Authors: Kaluza Miriam
Published: December 2020

The dissertation is dealing with four conservative bestselling authors who celebrated their first successes in the Weimar Republic, did not leave Germany after 1933 and dominated the literary field until the 1950s: Werner Bergengruen, Hans Carossa, Reinhold Schneider and Ernst Wiechert. The work does not focus on the question of the proximity or distance of these authors to the Nazi regime, but on their interpretation of the present and their self-presentation between 1930 and 1950. The search for orientation and self-positioning of these authors are outlined in case studies. In addition, the common poetic strategies are presented systematically.
Ubiquitination and Deubiquitination in Melanoma Research and Clinically Relevant Outcomes
Authors: Guo Jia , Zhang Jianglin
Published: December 2020

Malignant melanoma is one of the most invasive tumors with increasing mortality, low overall survival rates and limited effective therapeutic strategies. Ubiquitination is a post-translational protein modification, which is regulated by a series of ubiquitination-associated enzymes. Ubiquitination plays a critical role in diverse pathophysiological activities of cellular and participates in the pathogenesis of various cancers, including melanoma. This study aims to provide a conclusive of ubiquitination and deubiquitination, and their potential clinical application value in melanoma in the following aspects: melanoma pathogenesis-related components and processes in the ubuiquitin-proteasome system (UPS), ubiquitination in melanoma immunological microenvironment modulation, ubiquitination of key transcription factors in melanoma and melanoma therapeutic strategy via targeting the UPS.
Kisspeptin: Role in Female Infertility
Authors: Kükürt Abdulsamed , Kuru Mushap , Faruk Başer Ömer , Karapehlivan Mahmut
Published: December 2020

Kisspeptin is a neuropeptide encoded by the kisspeptin gene (Kiss1) and located in different brain regions, primarily in the hypothalamus. Kisspeptin and its receptor G-protein-coupled receptor-54 (GPR54), are also found in behavioural brain regions such as the hippocampus and cortex. Kisspeptin, a very powerful neuropeptide that stimulates the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary, does this by increasing gonadotropin-releasing hormone (GnRH) levels. In recent studies, it has been noted that kisspeptin is effective on reproductive functions. Globally 8 to 12% of couples have infertility problems, and the majority are residents of developing countries. Approximately 70% of infertility cases are caused by fertility problems in women. The frequency of infertility in women continues to increase every year and the underlying factors require further research. Bearing this problem in mind, this review examines the possible role of kisspeptin in female infertility. In doing so, it aims to find out how future application of kisspeptin may potentially unravel the neural reproductive disorder.
Providing a Framework for Testing the Reasonableness of Terminal Period Cash Flow Investments
Authors: Thompson Joseph , Neuzil David
Published: December 2020

Whether using the traditional Gordon Growth formula or the value driver formula, it is common for a valuer to neglect testing the reasonableness of the capitalized free cash flow used in determining the terminal value and, therefore, derive a terminal value that is incorrect. This is troubling considering how important the terminal value is when concluding an equity value; the terminal value most often accounts for a majority of the concluded enterprise value when applying the Discounted Cash Flow method. The purpose of this article is to provide a framework for testing the reasonableness of the amount of terminal cash flow that is reinvested to support the operations into perpetuity. In general, there are three potential areas for a company to reinvest into its future operations: (1) net working capital, (2) purchases of property, plant, and equipment (PP&E), and (3) other investments (e.g., research and development [R&D]). Our article provides an overview of a suggested method for analyzing and calculating the appropriate amount of investments in net working capital and PP&E under the Gordon Growth formula. We also provide an example analysis to illustrate potential issues resulting from expensed investments (e.g., R&D) when applying the value driver formula.
Self-Coping Strategies Among Jordanian Athletes During Ramadan Fasting: A Questionnaire Proposal
Authors: Djemai Haidar , Hammad Rami , Al Qarra Salem , M Dabayebeh Ibrahim
Published: December 2020

: This study aims to categorize the adaptation strategies of Muslim athletes who fast during Ramadan and proposes a self-coping strategy questionnaire as a complementary assessment tool. A total of 109 Jordanian Muslim athletes (mean age 20.0 ± 8.5 years) were surveyed by completing a self-coping questionnaire designed to classify an individual athlete’s level of adaptation. This study was conducted during the month of Ramadan 2019 and developed based on the training, nutritional, psychological, self-control, and recovery dimensions. Seventy percent of athletes found that they developed good or very good coping mechanisms. Coping strategies vary from one dimension to another, but in general, athletes often had a positive perceived coping. Athletes expressed that they are shifting the training hours with a preference for quality training rather than quantity and associated with a longer rest time. In addition, they were in favor of food hygiene associated with a strategy of sharing meals and providing water. The majority (59%) of the athletes said they were psychologically prepared for the potential effects of fasting. This research shows that athletes develop self-adjusting strategies to counter the effects of fasting. The questionnaire on the self-coping strategies provides important and precise information on the level of coping achieved by the athletes.
Samotherium Major, 1888 (Giraffidae) skullsfrom the late Miocene Maragheh fauna (Iran)and the validity of Alcicephalus Rodler & Weithofer, 1890
Authors: PARIZAD Elnaz , ATAABADI Majid MIRZAIE , MASHKOUR Marjan , KOSTOPOULOS Dimitris S.
Published: December 2020

Samotherium Major, 1888 (Giraffidae) is recorded from several late Miocene localities, primarily in the Balkans, the northern Black Sea region, Anatolia, central Asia and China. The first complete cranial material, with several mandibular rami, and postcranials of Samotherium are described here from the Middle Maragheh sequence in northwest Iran. The Maragheh taxon appears metrically and morphologically similar to the smaller Samotherium taxon from the Samos Island (Greece) referred to as S. boissieri Major, 1888, type species of the genus. These new data trigger further discussion about the Iranian Samotherium record, including Alcicephalus Rodler & Weithofer, 1890, which was recently resurrected as a valid genus in the Maragheh fauna. Our analysis of the material referred to this genus indicates that Samotherium is the most likely attribution for the Maragheh A. neumayri Rodler & Weithofer, 1890. Differences between S. boissieri and S. neumayri are more pronounced in postcranial elements than in cranial and dental ones and need further investigation.
Living and working with giants: a multispecies ethnography of the Khamti and elephants in Northeast India
Authors: Lainé Nicolas
Published: December 2020

This book proposes a unique and immersive multispecies ethnography of the cooperative interaction between the Khamti and elephants in Northeast India. It is based on extended research fieldwork, which attempts not only to describe how the Khamti establish working relationships with elephants, but also considers the involvement of animals in this joint-venture. Through a step-by-step approach, the book addresses different aspects of the interspecies working unit from the beginning of Khamti-elephant association through to its evolvement at work. Back and forth from village to forest, through rich and meticulous descriptions, Nicolas Lainé brings the reader up close in following the capture of a juvenile forest elephant, documenting its transformation into a village elephant. In this unique way, Lainé shows how the initial human-animal bonds evolve and persist at work as a two-way, reciprocated process. The adopted multi-disciplinary approach allows thinking the human-elephant working unit in terms of intersubjective engagement. In its analysis, Nicolas Lainé took into consideration of the cognitive capacities and corporeal capabilities of humans and elephants, their reciprocal influences, and the representations that arise from specific contexts in which interspecies communication and collaboration is manifest. Hence, the proposition on interspecies labour sheds new light not only with respect to what we know (or we think we know) about animals, but also modifies our idea of domestication. At the workplace, humans and animals not only partake in a common world, but that they produce this world together and transform it through their collaboration. Beyond this, the book shows how the quality of shared living conditions for both animal and human are intrinsically linked. It opens doors to a new approach of species conservation and the realization of a very current and widespread aspiration: that of extending the mutually beneficial modalities of existence of humans and animals in their shared environment.
A Philosophy of Madness
Authors: Kusters Wouter
Published: December 2020

The philosophy of psychosis and the psychosis of philosophy: a philosopher draws on his experience of madness.

In this book, philosopher and linguist Wouter Kusters examines the philosophy of psychosis—and the psychosis of philosophy. By analyzing the experience of psychosis in philosophical terms, Kusters not only emancipates the experience of the psychotic from medical classification, he also emancipates the philosopher from the narrowness of textbooks and academia, allowing philosophers to engage in real-life praxis, philosophy in vivo. Philosophy and madness—Kusters's preferred, non-medicalized term—coexist, one mirroring the other.

Kusters draws on his own experience of madness—two episodes of psychosis, twenty years apart—as well as other first-person narratives of psychosis. Speculating about the maddening effect of certain words and thought, he argues, and demonstrates, that the steady flow of philosophical deliberation may sweep one into a full-blown acute psychotic episode. Indeed, a certain kind of philosophizing may result in confusion, paradoxes, unworldly insights, and circular frozenness reminiscent of madness. Psychosis presents itself to the psychotic as an inescapable truth and reality.

Kusters evokes the mad person's philosophical or existential amazement at reality, thinking, time, and space, drawing on classic autobiographical accounts of psychoses by Antonin Artaud, Daniel Schreber, and others, as well as the work of phenomenological psychiatrists and psychologists and such phenomenologists as Edmund Husserl and Maurice Merleau-Ponty. He considers the philosophical mystic and the mystical philosopher, tracing the mad undercurrent in the Husserlian philosophy of time; visits the cloud castles of mystical madness, encountering LSD devotees, philosophers, theologians, and nihilists; and, falling to earth, finds anxiety, emptiness, delusions, and hallucinations. Madness and philosophy proceed and converge toward a single vanishing point.
Status Quo and Innovative Directions for Inpatient Fall Interventions
Authors: Lee Ji Yea , Lee Juhee , Jang Yeonsoo , Kim Eun Chae , Ji Yong Gu , Park Taezoon , Um Sang Yoon , Cha Min Chul , Kim Yielin
Published: December 2020

Purpose: The purpose of this study was to explore nurses’ experience of falls, and their perception of the status quo of inpatient fall interventions.Methods: The participants were 28 ward nurses in a university hospital, Seoul, Korea. Five focus group interviews and three individual interviews were conducted. The interviews were analyzed using thematic analysis.Results: The findings from this study suggest that nurses face limitations in providing conventional fall interventions due to patient disease related characteristics, situations in hospital, and medical devices used in the hospital settings. Although nurses adopted their own strategies to prevent falls effectively, they expressed the need for innovative approaches to overcome these limitations.Conclusion: Systematic, technology-based approaches are needed to create a safer physical environment and to improve current nursing interventions to prevent falls.
Claves para la comprensión de la nueva legislación de arrendamientos de vivienda en Venezuela.
Authors: Lovera De Sola Irma Isabel
Published: December 2020

Este trabajo intenta dar una visión panorámica de la nueva Ley para la Regularización y Control de los Arrendamientos de Vivienda promulgada en Venezuela en noviembre de 2011 y su impacto sobre el derecho de propiedad y la concepción tradicional del contrato de arrendamiento.
Impact of COVID-19 on the Nigerian Educational System: Strengths and Challenges of Online/Virtual Education
Authors: Agbele Alaba Tolulope , Oyelade Emmanuel Akinbami
Published: December 2020

Coronavirus disease 2019 (COVID-19) which originated in Wuhan, China, in December 2019, was declared as a pandemic by World Health Organization (WHO) on 11th of March, 2020 after it has spread to many countries of the world. It has also caused more than 171 countries of the world to close their educational institutions for several months in the year 2020. The impact of COVID-19 on education is bizarre and unprecedented in history because more than 1.5 billion students from across the globe have been affected by school closure. Most Nigerian students and other African or underdeveloped countries were more disadvantaged because most educational institutions in Nigeria still follow the traditional set-up of face-to-face lectures in the normal classroom settings.  This opinion article highlights the importance of online education in a time of global pandemic and natural disaster. It also examines the strengths and challenges of online education.
An efficient, high‐throughput method for the simultaneous exposure of drought stress and bacterial infection in plants
Authors: Choudhary Aanchal , Senthil‐Kumar Muthappa
Published: December 2020

Premise

We developed a systematic protocol for the easy, high‐throughput, qualitative, and quantitative assessment of the patho‐morphological, physiological, and molecular responses of Arabidopsis thaliana plants simultaneously subjected to drought and bacterial infection. This approach will assist studies elucidating plant adaptation strategies to combat combined stresses.

Methods and Results

Plants were grown in small screw‐capped containers, individual pots, or pot strips. Watering was withheld from 30‐day‐old plants, which were subsequently infected with Pseudomonas syringae pv. tomato DC3000 using a dip inoculation. The natural development of both drought and bacterial infection was successfully and rapidly replicated in large numbers of plants, which is difficult to achieve with existing protocols.

Conclusions

Our protocol offers a simple, low‐cost, high‐throughput strategy for the rapid and easy bacterial infection of large numbers of plants. It can be used in large‐scale mutant and ecotype screenings under combined stresses and for other foliar pathogens in different plant species.
Diffuse lesions secondary to sarcoidosis mimicking widespread metastatic breast cancer: A case report
Authors: Vieira Heidi , Neilsen Beth K. , Sleightholm Richard , Hankins Jordan , Freifeld Alison , Moore Gerald , Wahl Andrew , Baine Michael J.
Published: December 2020

This case of sarcoidosis mimicking metastatic breast cancer serves as a reminder of the need to consider differential diagnoses even when the clinical scenario and imaging findings are highly suggestive of metastases.
Über den Tellerrand blicken: interdisziplinär und international
Authors: Bengs Holger
Published: December 2020

Das European Chemistry Partnering entstand aus der Idee, Startups einen Marktplatz zu bieten. Heute ist es das Industry Business Speed Dating. Das ECP führt alle Spieler entlang der chemischen Wertschöpfung zueinander, von der Basischemie bis zu Konsumgüt
Leichtgewichtig aber hart im Nehmen
Authors: Maiwald Markus
Published: December 2020

Behälter aus glasfaserverstärktem Kunststoff (GFK) haben das Ende ihrer rechnerischen Lebensdauer nach 200.000 Betriebsstunden erreicht. Klare Aussagen zum Zustand des Behälters liefert die Begutachtung vor Ort und — falls notwendig — auch die Analyse von
Digitalisierung und Alarmmanagement
Authors: Kerzmann Guido
Published: December 2020

Je komplexer verfahrenstechnische Abläufe und damit auch der Automatisierungsgrad der beteiligten Anlagen sind, desto mehr Alarme müssen von den Operatoren in der Leitwarte und in der Produktion verarbeitet werden — mehrere Tausend pro Tag sind keine Selt
Modulare Anlagen zulassen
Authors: Neupert Michael
Published: December 2020

Modulare Anlagen sind auf Grundlage des geltenden Immissionsschutzrechts zulassungsfähig. Gesetzliche Neuregelungen sind für modulare Anlagen damit grundsätzlich entbehrlich; ob inkrementelle Anpassungen erforderlich sind, wird die Zeit zeigen. Klar ist,
Pregnancy after breast cancer: Results from a prospective cohort of young women with breast cancer
Authors: Poorvu Philip D. , Gelber Shari I. , Zheng Yue , Ruddy Kathryn J. , Tamimi Rulla M. , Peppercorn Jeffrey , Schapira Lidia , Borges Virginia F. , Come Steven E. , Lambertini Matteo , Rosenberg Shoshana M. , Partridge Ann H.
Published: December 2020

Background

Many young women with newly diagnosed breast cancer are interested in future pregnancies. Prospective data regarding fertility interest and reproductive patterns after diagnosis are needed to counsel patients.

Methods

The Young Women's Breast Cancer Study is a multicenter, prospective cohort of women who were diagnosed with breast cancer at age ≤40 years between 2006 and 2016. Women complete surveys at baseline, every 6 months for 3 years, then annually. Here, the authors describe fertility interest and pregnancies within 5 years of diagnosis for women with stage 0 through III breast cancer.

Results

Of 1026 eligible participants, 368 (36%) reported interest in future biologic children at least once within 5 years after diagnosis, including 16% at 5 years after diagnosis. Among 130 women who attempted to become pregnant, 90 (69.2%) conceived; and, among 896 women who did not attempt to conceive, 18 (2.0%) became pregnant, with a total of 152 pregnancies resulting in 91 live births. Factors associated with pregnancy included younger versus older age at diagnosis (aged ≤30 vs 36‐40 years: odds ratio [OR], 6.63; 95% CI, 3.18‐13.83; P < .0001; aged 31‐35 vs 36‐40 years: OR, 5.86; 95% CI, 3.37‐10.17; P < .0001) and being nulliparous versus parous (OR, 2.66; 95% CI, 1.56‐4.53; P = .001). The receipt of endocrine therapy versus no endocrine therapy (OR, 0.35; 95% CI, 0.20‐0.59; P = .001) was inversely associated with pregnancy.

Conclusions

Many women remain interested in future fertility in the 4 years after a breast cancer diagnosis, indicating that longitudinal fertility discussions are needed. Although a minority of those interested in having children attempted to become pregnant in the first 5 years, most who attempted to conceive did so and had live births.
K‐ear: Extracting data access periodic characteristics for energy‐aware data clustering and storing in cloud storage systems
Authors: You Xindong , Sun Tian , Sun Dawei , Liu Xunyun , Lv Xueqiang , Buyya Rajkumar
Published: December 2020

Rapid increase in energy consumption is a serious problem in cloud storage systems. Data accessed in large‐scale storage systems usually exhibit temporal and spatial characteristics, which make it possible to reduce energy consumption by clustering data with similar access characteristics for storage in the same zone of cloud storage systems. Existing works usually only focus on the frequency of data access. However, widely existing phenomena show data access with seasonal and tidal characteristics in cloud storage systems. The seasonal and tidal characteristics of data access are extracted thoroughly in this paper. According to the extracted data access characteristics, energy‐aware data clustering through a machine learning algorithm (K‐ear) is proposed. K‐ear classifies data into five seasonal categories according to their seasonal access characteristics and then classifies every seasonal category into three tidal categories according to its tidal access characteristics. The 15 classified categories are stored in different storage zones with different energy and performance modes. Simulation experiments using CloudSimDisk with the constructed mathematic models demonstrate that the proposed K‐ear algorithm is more energy‐efficient than the default data clustering algorithms in Hadoop and the classical data clustering storage strategy according to the data access frequency (Striping‐Based Energy‐Aware Strategy).
The impact of Corporate Social Responsibility on Corporate Image: Evidence of budget airlines in Europe
Authors: Streimikiene Dalia , Lasickaite Kristina , Skare Marinko , Kyriakopoulos Grigorios , Dapkus Rimantas , Duc Pham Anh
Published: December 2020

There is growing scientific debate on the impact of Corporate Social Responsibility (CSR) or Corporate Hypocrisy (CH) on Corporate Reputation (CR). The aim of the study is to analyse the influence of CSR on CR based on literature review and results of conducted empirical studies and to test this relationship in growing budget airlines sector. Environmental responsibility of airlines was highlighted in this study. The empirical study conducted in Lithuania employed quantitative survey. And 400 adults were surveyed. The results indicated that CSR and CR in the budget airline sector are important for the Lithuanian customers. However, the study did not find the link between agreeing to pay a higher price for flight operated by socially responsible companies and the importance of airlines' CR in making a purchase decision. There was also no link found between the more frequent choice of flights operated by airlines conducting CSR activities and the importance of the airlines' CR in the purchasing decision. The relationship between airlines ‘past actions that determine their CR and the predictability of airlines' future actions were also found to be weak.
Woodsmith project – Construction of a 37 km long mineral transport system for the world's largest Polyhalite resource
Authors: Gschnitzer Ernst , Wenger Julian , Raine Andy
Published: December 2020

Rapidly increasing and urbanized world populations require the use of fertiliser for more efficient food production. Polyhalite provides this by sustainable and low carbon means. The world's largest known high‐grade Polyhalite deposit is located under the North York Moors National Park in the north‐east of England at a depth of about 1,550 m. In order to protect the national park, the mineral is processed outside the park on the coast near Wilton, Teesside. The mineral is transported there on a conveyor belt running in a 37 km long tunnel between the Woodsmith mine and the portal in Wilton. Strabag was awarded with the design and construction of the 37 km long tunnel, including the mineral transport system. The total contract value amounts to several hundred million Euros with a 100 % share for Strabag. The biggest challenges for this very long tunnel drive are especially the logistics. High safety standards and a tight time schedule, funding issues and contractual changes have resulted in additional challenges. Close cooperation with the Client's team on site has been key for achieving best results for the project.
Design of a NATM crossover at Mumbai metro line 3
Authors: Panwar Akshay , Manvani Jitendra , Muniyappa Prathap , Krenn Florian
Published: December 2020

The construction of underground structures in metro rail projects is always challenging as the project works normally affect a large number of adjacent surface structures with stringent settlement criteria and protection requirements. Project implementation becomes even more complex when the overburden is shallow and the area of the cross‐section is comparatively large. In the case of design and build metro rail projects, the Client provides a tender stage design to the Contractor's designer; this initial design is often based on limited data and does not consider the construction phase in detail. This is a significant challenge for the Contractor's designer as the new design has to consider all relevant parties and boundary conditions with respect to the compatibility of other parts of the project. This paper describes such a challenge at Mumbai metro line 3, where a crossover structure had to be implemented during the detailed design as a change of scope. The initially proposed crossover cavern was re‐arranged during the detailed design. The main emphasis of this paper is to explain the revised crossover arrangement, for optimized construction feasibility, construction staging and geotechnical stability of the excavation. After the options presented by the Contractor's designer met the original objectives, the detailed design of the primary support and modified construction sequence was carried out in accordance with the principles of NATM design.
The Shazar caverns – Design challenges and construction experience
Authors: Schürch Roberto , Perazzelli Paolo , Moranda Giuseppe , Spivak Eldad
Published: December 2020

The Shazar caverns (width 19 m, height of 29 m, length 270 m) are part of the first phase of a larger project called the “Jerusalem Gateway”. They will accommodate a road in the upper level and five parking floors in the lower levels. The geology in the project area is characterized by dolomite and dolomitic limestone, overtopped by decayed rock including significant clay masses and artificial filling. Overall, the rock mass is weathered due to strong karst activity. The peculiarities of the project are the small overburden (7 to 10 m) under poor ground conditions, the close vicinity between the caverns and existing/future buildings (2 to 5 m), the vicinity between the two caverns (3 to 5 m), the intense earthquake activity in the area and the presence of large karstic cavities. The resulting challenges require unique engineering solutions. This paper gives an overview on the project, it presents the adopted design approach and the elaborated design solutions and, finally, it shows the construction experience.
A mental health course for developmental allied healthcare professionals: An exploration of potential effectiveness
Authors: Zohar Orna , Sher‐Censor Efrat , Elata Judith
Published: December 2020

We examined the effectiveness of a mental health course for developmental allied healthcare professionals (DAHPs) that focused on emotional and relational processes inherent to treatment. We hypothesized that (a) following the course, DAHPs would report increased awareness and sense of competence in dealing with these processes; (b) an increased sense of competence would be associated with decreased burnout; (c) following the course, DAHPs would increase their reading and participation in seminars about emotional processes in therapy; and (d) DAHPs would report the course had positive effects on their work and that they use a more relationship‐based treatment approach. Participants were 153 Israeli DAHPs. They reported their attitudes and sense of competence in coping with emotional and relational processes in treatment in three time points: before, upon completion, and at follow‐up. At follow‐up, participants also reported level of burnout and the extent they made changes in their work. They provided examples of these changes, which were qualitatively analyzed. Study hypotheses were supported. Results suggest participating in a relatively brief mental health course is associated with positive changes in DAHPs’ attitudes, sense of competence, and professional approach toward a relationship‐based treatment.
Equivalence relations and the contextual control of multiple derived stimulus functions
Authors: Perez William F. , de Azevedo Sunna P. , Gomes Cainã T. , Vichi Christian
Published: December 2020

Contextual control is a key aspect in equivalence research to support the claim that stimuli may have multiple functions or symbols may have multiple meanings. The present study investigated the contextual control of multiple derived stimulus functions in two experiments. In Experiment 1, equivalence classes were formed and one stimulus set from each class was used to establish two different functions: one via positive reinforcement (key‐pressing) and another via negative reinforcement (button clicking), both under contextual control of two different background colors. Later, other stimuli from the equivalence class were presented on those background colors and contextual control of multiple derived stimulus functions was assessed. Experiment 2 added a third background in which no programmed response was reinforced, that is, responses were extinguished. Transfer‐of‐function tests revealed contextual control of three different functions, including derived extinction. Implications for equivalence relations as a behavior‐analytical model of symbolic functioning are discussed.
A case‐control emergency department‐based analysis of acute pancreatitis in Covid‐19: Results of the UMC‐19‐S6
Authors: Miró Òscar , Llorens Pere , Jiménez Sònia , Piñera Pascual , Burillo‐Putze Guillermo , Martín Alfonso , Martín‐Sánchez Francisco J , Lamberechts Jorge , Alquézar‐Arbé Aitor , Jacob Javier , Noceda José , Cano Cano María J , Fortuny Bayarri María J , Marín Porrino Juan M , Meléndez Napoleón , Pérez García Carles , Brasó Aznar José V , Ponce María C , Díaz Fernández Elena , Ejarque Martínez Laura , Peiró Gómez Ana , Tost Josep , Domínguez María J , Teigell Muñoz Francisco J , González del Castillo Juan ,   the Spanish Investigators on Emergency Situations TeAm (SIESTA) network
Published: December 2020

Background/Purpose

We investigated the incidence, risk factors, clinical characteristics and outcomes of acute pancreatitis (AP) in patients with COVID‐19 attending the emergency department (ED), before hospitalization.

Methods

We retrospectively reviewed all COVID patients diagnosed with AP in 62 Spanish EDs (20% of Spanish EDs, COVID‐AP) during the COVID outbreak. We formed two control groups: COVID patients without AP (COVID‐non‐AP) and non‐COVID patients with AP (non‐COVID‐AP). Unadjusted comparisons between cases and controls were performed regarding 59 baseline and clinical characteristics and four outcomes.

Results

We identified 54 AP in 74 814 patients with COVID‐19 attending the ED (frequency = 0.72‰, 95% CI = 0.54‐0.94‰). This frequency was lower than in non‐COVID patients (2231/1 388 879, 1.61‰, 95% CI = 1.54‐1.67; OR = 0.44, 95% CI = 0.34‐0.58). Etiology of AP was similar in both groups, being biliary origin in about 50%. Twenty‐six clinical characteristics of COVID patients were associated with a higher risk of developing AP: abdominal pain (OR = 59.4, 95% CI = 23.7‐149), raised blood amylase (OR = 31.8; 95% CI = 1.60‐632) and vomiting (OR = 15.8, 95% CI = 6.69‐37.2) being the strongest, and some inflammatory markers (C‐reactive protein, procalcitonin, platelets, D‐dimer) were more increased. Compared to non‐COVID‐AP, COVID‐AP patients differed in 23 variables; the strongest ones related to COVID symptoms, but less abdominal pain was reported, pancreatic enzymes raise was lower, and severity (estimated by BISAP and SOFA score at ED arrival) was higher. The in‐hospital mortality (adjusted for age and sex) of COVID‐AP did not differ from COVID‐non‐AP (OR = 1.12, 95% CI = 0.45‐245) but was higher than non‐COVID‐AP (OR = 2.46, 95% CI = 1.35‐4.48).

Conclusions

Acute pancreatitis as presenting form of COVID‐19 in the ED is unusual (<1‰ cases). Some clinically distinctive characteristics are present compared to the remaining COVID patients and can help to identify this unusual manifestation. In‐hospital mortality of COVID‐AP does not differ from COVID‐non‐AP but is higher than non‐COVID‐AP, and the higher severity of AP in COVID patients could partially contribute to this increment.
Feller semigroups and degenerate elliptic operators III
Authors: Taira Kazuaki
Published: December 2020

This paper is devoted to the functional analytic approach to the problem of construction of Feller semigroups in the characteristic case via the Fichera function. Probabilistically, our result may be stated as follows: We construct a Feller semigroup corresponding to such a diffusion phenomenon that a Markovian particle moves continuously in the interior of the state space, without reaching the boundary. We make use of the Hille–Yosida–Ray theorem that is a Feller semigroup version of the classical Hille–Yosida theorem in terms of the positive maximum principle. Our proof is based on a method of elliptic regularizations essentially due to Oleĭnik and Radkevič. The weak convergence of approximate solutions follows from the local sequential weak compactness of Hilbert spaces and Mazur's theorem in normed linear spaces.
Durchstarten mit Peptiden
Authors: Mayer Christian
Published: December 2020

Wie könnte das Leben auf der Erde entstanden sein? Wie könnte es auf fremden erdähnlichen Himmelskörpern entstehen? Um diese Fragen zu beantworten, ist ein Prozess zu ermitteln, der von der Chemie auf der frühen Erde zur Ordnung und Komplexität lebender Systeme führt. Grundlage für eine spontane Evolution könnten peptidbeladene Vesikel sein.
Statt Versuch und Irrtum: Software entwickelt Methoden
Authors: Ehrensberger Christian
Published: December 2020

Eine HPLC‐Methode für mehrere Analyten zu entwickeln, kostet Zeit. Spezialisierte Softwarepakete können heute die Zahl der erforderlichen Experimente und den Aufwand für die Methodenentwicklung reduzieren. Die Methoden lassen sich robuster gestalten, und die Validität wird für Kontrollbehörden nachvollziehbar dokumentiert.
Correlation between lactate dehydrogenase/pyruvate dehydrogenase activities ratio and tissue pH in the perfused mouse heart: A potential noninvasive indicator of cardiac pH provided by hyperpolarized magnetic resonance
Authors: Shaul David , Azar Assad , Sapir Gal , Uppala Sivaranjan , Nardi‐Schreiber Atara , Gamliel Ayelet , Sosna Jacob , Gomori J. Moshe , Katz‐Brull Rachel
Published: December 2020

Cardiovascular diseases account for more than 30% of all deaths worldwide and many could be ameliorated with early diagnosis. Current cardiac imaging modalities can assess blood flow, heart anatomy and mechanical function. However, for early diagnosis and improved treatment, further functional biomarkers are needed. One such functional biomarker could be the myocardium pH. Although tissue pH is already determinable via MR techniques, and has been since the early 1990s, it remains elusive to use practically. The objective of this study was to explore the possibility to evaluate cardiac pH noninvasively, using in‐cell enzymatic rates of hyperpolarized [1‐13C]pyruvate metabolism (ie, moles of product produced per unit time) determined directly in real time using magnetic resonance spectroscopy in a perfused mouse heart model. As a gold standard for tissue pH we used 31P spectroscopy and the chemical shift of the inorganic phosphate (Pi) signal. The nonhomogenous pH distribution of the perfused heart was analyzed using a multi‐parametric analysis of this signal, thus taking into account the heterogeneous nature of this characteristic. As opposed to the signal ratio of hyperpolarized [13C]bicarbonate to [13CO2], which has shown correlation to pH in other studies, we investigated here the ratio of two intracellular enzymatic rates: lactate dehydrogenase (LDH) and pyruvate dehydrogenase (PDH), by way of determining the production rates of [1‐13C]lactate and [13C]bicarbonate, respectively. The enzyme activities determined here are intracellular, while the pH determined using the Pi signal may contain an extracellular component, which could not be ruled out. Nevertheless, we report a strong correlation between the tissue pH and the LDH/PDH activities ratio. This work may pave the way for using the LDH/PDH activities ratio as an indicator of cardiac intracellular pH in vivo, in an MRI examination.
A two‐step optimization model for the distribution of perishable products
Authors: Gaggero Mauro , Tonelli Flavio
Published: December 2020

Optimal planning for distribution networks of perishable products is addressed by means of a two‐step approach pursuing both strategic and tactical goals. The distribution network is represented as a directed graph, and discrete‐time dynamic equations are devised to model the storage and transportation of products. The first decision step consists of an optimization problem to account for a strategic viewpoint. In particular, this problem allows to select optimal values for replenishment cycles of products, safety stocks, and amounts of products to be transferred among the nodes of the network by considering uncertainty on long‐term demand predictions. The second decision step requires the solution of rolling‐horizon optimization problems at the various time buckets that exploit accurate, short‐term predictions of customers' demands according to a tactical perspective. In this case, the strategic decisions on the amounts of products to be transferred are tuned according to the available short‐term predictions of demands. The effectiveness of the proposed approach is showcased by simulations in a case study, in comparison with a classical lot‐for‐lot strategy.