bluuebunny/crossref_metadata_2025 huggingface dataset:
К вопросу об определении понятия «предпринимательская среда»
Authors: Перфильев Сергей Валерьевич , Авилкина Светлана Викторовна
Published: April 2019

Понятием «предпринимательская среда» активно оперируют исследователи, представители государственных органов власти, представители бизнеса, широкая общественность. Однако определение исследуемого понятия отсутствует в энциклопедических изданиях, ученые достаточно широко трактуют понятие «предпринимательская среда».
В статье исследованы теоретические подходы к определению понятия «предпринимательская среда». В ходе исследования приведены варианты определения составляющих компонентов данного термина, которые предлагаются энциклопедическими изданиями; исследована распространенность применения термина. Проведен обзор существующих трактовок исследуемого понятия.
В ходе анализа опубликованных в Российской Федерации научных и учебно-методических трудов авторы статьи обозначают следующие неточности, встречающиеся при определении понятия: часто «предпринимательская среда» представляется в виде «ситуации» или в виде «процесса»; отмечается только положительное влияние предпринимательской среды на развитие предпринимательства.
Авторами статьи предложены два подхода к определению исследуемого понятия, которые могут быть использованы при проведении научных исследований. Первый подход основан на представлении предпринимательской среды в виде совокупности факторов (для исследования предпринимательской среды применим факторный анализ). Второй подход основан на том, что предпринимательская среда может быть описана, смоделирована как социально-экономическая система (в этом случае применима теория систем).
Представленные в статье результаты исследования могут быть использованы специалистами в области предпринимательства, экономистами, предпринимателями.
Grupo Tutorial em Saúde Bucal: a experiência em atenção primária no Centro de Saúde do Itapoã-DF
Authors: Souza Tiago Araújo Coelho de , Ramos Maria Do Carmo Toledo , Franco Juliana Fiuza , Moura Regina Cardoso de , Moita Marina Meirelles Bogalho , Vilela Lorena Gonçalves , Nunes Gratia Patricia Lucatelli , Chupel Marcelle Cristina Simioni , Barbosa Clarissa Borges , Junqueira Larissa Gavião , Stypulkowski Renata Porto , Silva Renato Costa Vieira da
Published: April 2019

Este artigo apresenta o relato de experiência do Programa de Educação Tutorial em Odontologia da Universidade de Brasília, durante o período de março a dezembro de 2010. O cenário de prática das atividades de campo é a Regional Administrativa do Itapoã, no Distrito Federal, e a atuação do grupo tutorial acontece junto às Equipes de Saúde da Família por meio de rotinas educativo-preventivas em saúde bucal durante as visitas domiciliares, atividades clínicas e desenvolvimento de pesquisas. Alunos e preceptores estão sendo capazes de reconhecer os determinantes sociais do processo saúde-doença, analisar os indicadores de saúde bucal da população, aprimorar práticas educativas utilizadas na Estratégia Saúde da Família e promover saúde no âmbito da comunidade. As principais dificuldades encontradas dizem respeito a limitação de espaço físico e de recursos capazes de atender a demanda do grupo tutorial e das famílias assistidas. Esta experiência tutorial junto à Estratégia Saúde da Família possibilita um aprendizado que vai muito mais além do que a tradição de ensino bio-tecnicista da odontologia, bem como permite aos discentes de odontologia da UnB ‘vivenciar uma experiência real’ e refletir sobre os conhecimentos teóricos obtidos nos ‘bancos da universidade’.
当前地质矿产勘查及找矿技术探析
Authors: 虎 金
Published: April 2019

随着社会经济的快速发展，对矿产资源的需求量也与日俱增，传统的地质矿产勘查找矿技术弊端已经逐渐暴露出来，不能满足相关工作的实际需求，企业必须要树立创新意识，融入现代化、智能化元素，积极加强技术革新，将这些先进科技应用到地质矿产勘查找矿工作中，以提高找矿效率，将矿产资源最大程度的挖掘出来，在此情况下企业的经济效益必然能够得到大幅度的提升，同时还能够进一步推动国家的发展建设步伐。
Sudden cardiac death (SCD) and sudden unexpected death in epilepsy (SUDEP)
Authors: Mańka-Gaca Iwona , Łabuz-Roszak Beata
Published: April 2019

Nagłe niespodziewane zgony u osób dotychczas uważanych za zdrowe stanowią istotne wyzwanie dla współczesnej medycyny. Wciąż poszukuje się przyczyn tego zjawiska i próbuje poznać jego patomechanizm. Wśród osób szczególnie narażonych znajdują się osoby chorujące na padaczkę. Każdy niespodziewany zgon u chorego na padaczkę, którego ogólny stan zdrowia był dobry, aktywność życiowa normalna i u którego nie znaleziono innej przyczyny chorobowej tego zdarzenia, określa się terminem nagłej niespodziewanej śmierci u chorych na padaczkę (sudden unexpected death in epilepsy – SUDEP). Pomimo trudności w przewidywaniu nagłych zgonów szczególnym nadzorem należy objąć osoby z grupy podwyższonego ryzyka, do których niewątpliwie należą chorzy z chorobami układu sercowo-naczyniowego oraz z padaczką.
Implantation of Nellix system in treatment of type IIIA leak in patient with stent graft of abdominal aorta
Authors: Ratman Rajmund , Kuśmierz Janusz , Wojczyk Sławomir
Published: April 2019

Chory 50-letni, po implantacji stentgraftu Jotec do aorty brzusznej w 2014 r., pozostający pod stałą opieką Poradni Chorób Naczyń Wojewódzkiego Szpitala Specjalistycznego nr 4 w Bytomiu, zgłosił się na oddział z podejrzeniem przecieku typu IIIA. Obecność przecieku potwierdzono w badaniu angio-TK. Na podstawie wykonanych badań chorego zakwalifikowano do implantacji systemu Nellix do stentgraftu Jotec. Operowany 19.10.2017 r. Przebieg operacji bez powikłań, po implantacji w kontrolnej aortografii bez cech przecieku. W kontrolnym angio-TK miesiąc po leczeniu operacyjnym nie uwidoczniono przecieku, stenty systemu Nellix prawidłowo ułożone. Aktualnie pacjent przebywa w warunkach domowych, w stanie ogólnym dobrym. Ustalono termin kontroli, w tym ultrasonograficznej.
The possibilities of medicinal therapy in patients with calcined aortic stenosis
Authors: Andropova Olesya V. , Alekseeva L. A , Minushkina L. O
Published: April 2019

The calcined aortic stenosis is one of the most frequently occurring cardio-vascular diseases with unfavorable prognosis of treatment. Te actual conceptions of risk factors of development, pathogenesis and course of disease starting from inflammation and endothelial dysfunction and completing with bone metaplasia give an opportunity of determining prospective directions of medicinal therapy favoring deceleration of progressing of calcined aortic stenosis. The review summarizes main data of publications concerning attempts of pathogenetically medicinal impact on progressing of calcined aortic stenosis.
The neurobiologic aspects of photochromotherapy
Authors: Sorokina Nataliya D. , Selitskiy G. V , Dina E. S
Published: April 2019

The review summarizes and analyzes specters of therapeutic effect of laser and light-emitting diode radiation of different wavelengths as exemplified by various diseases. The physiological and certain biophysical differences in the basis of effect mechanisms of modern laser and light therapy are emphasized. The review applied both research studies and monographs and tutorials. Hence, a large volume of data was analyzed concerning every type of light therapy and its contraindications. The comparison is implemented concerning efficiency of implementation of red, blue and green light-emitting diode radiation in neurological, therapeutic, stomatological practice and in therapy of emotional conditions.
The ethics and medicine: certain little known pages of history of the Third Reich and USA
Authors: Damulin Igor V.
Published: April 2019

The article considers destinies of medics residing in Nazi Germany and invaded countries. They took no participation in resistance but they were annihilated mainly in ghettos and concentration camps. The particular attention is paid to physicians, including the field of neurological sciences, left memories of themselves in the form of eponym names. These eponyms are to be applied in practical activities. The information is cited concerning inhuman programs of sterilization and euthanasia existed in Nazi Germany. It is emphasized that these programs occurred not in empty place because background of their development existed before Nazi came into power and the uSA included. And at that, experiments with prisoners continued to be implemented in the uSA even after the Second world war. The article draws attention to the importance of ethic aspects in activities of medics.
THE EFFICIENCY OF ANTI-COAGULANTS APPLIED DURING TRANSCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME WITHOUT ELEVATION OF ST SEGMENT
Authors: Chernigina T. P , Goloshchapov-Aksenov R. S , Maksimkin Daniil A. , Sturov N. V , Shugushev Z. Kh
Published: April 2019

The purpose of study. To evaluate efficiency of different coagulants used under transcutaneous coronary interventions in patients with acute coronary syndrome without elevation of ST segment.The methods. The sampling of 346 patients was randomized in two groups. In the group I (n=155) transcutaneous coronary intervention was implemented using bivalirudin and in group II (n = 191) - using unfractionated heparin. The additional randomization of patients of group I: in subgroup A (n = 77) infusion of bivalirudin continued during four hours after intervention and in subgroup B (n = 78) infusion was discontinued in X-ray operating room. The criteria of inclusion: patients with acute coronary syndrome without elevation of ST segment with multi-vascular affection of coronary channel (risk on SYNTAX score = 23-32); high and medium degree of risk according GRACE scale; absence of re-vascularization of myocardium in anamnesis. The criteria of exclusion: patients with very high risk according GRACE scale; affection of left coronary artery trunk. The results. During period of hospitalization, total rate of intra- and post-operative cardiovascular complications had no reliable differences in two groups and amounted to 7.1% and 8.4% correspondingly (p = 0.6423). The serious bleedings (BARC 3 and 5) occurred reliably more frequently in patients of group II. Also, the groups had no differences in rate of development of acute thrombosis of stents. In subgroup A reliably less frequently occurred serious cardiovascular complications as compared with patients of subgroup B (1,3% и 13% correspondingly; р = 0,001). At that, rate of bleeding reliably had no differences. At trans-radial access, in patients of group I rate of bleeding and cardiovascular complications amounted to 0% and 2.9% and at trans-femoral access these indices were reliably higher - 3,3% и 10% correspondingly (р < 0,001). In group II a similar tendency is noted: at trans-radial access these indices amounted to 6% and 4.6% and at trans-femoral - 33.7% and 11.9% correspondingly (р
THE EVALUATION OF RISK FACTORS OF CARDIO-VASCULAR DISEASES IN PATIENTS WITH DIABETES MELLITUS TYPE II DEPENDING ON DEGREE OF COMPENSATION OF CARBOHYDRATE METABOLISM AND IN TREATMENT DYNAMICS
Authors: Stryuk R. I , Sviridova M. I , Golikova A. A , Lobanova E. G
Published: April 2019

The study was carried out using sampling of 74 patients (20 males and 54 females) aged from 48 to 75 years (average age 61.5±7.4 years) with diabetes mellitus type II. The analysis was applied to anthropometric parameters, lipid metabolism condition, level of highly sensitive C-reactive protein, tumor necrosis factor-α depending on degree of compensation of carbohydrate metabolism-level of glycosylated hemoglobin (HbA1c). In patients with diabetes mellitus type II with worse compensation of carbohydrate metabolism (HbA1c>7,5%) their body mass, waist circumference, body mass index occurred higher than in patients with HbA1c≤7,5%. The level of highly sensitive C-reactive protein corresponding to risk of development of cardio-vascular diseases was established in 97% of patients and increased level of tumor necrosis factor-α was established in 66% of patients independently of indices of glycemia. The patients were divided in 2 groups. The group I included 50 patients whose treatment was supplemented with mimetic of glucagon-like peptide Exenatid in the mode of double subcutaneous injections in dosage of 5 mkg 2 t per day during a month and then 10 mkg 2t per day during 5 months. The control group included 20 patients receiving a standard sugar-decreasing therapy. The initially analyzed indices had no statistically reliable differences in both groups. In patients of both groups a reliable decreasing of HbA1c was established in 6 months. Only in patients of group I statistically reliable amelioration of lipid specter, decreasing of body mass, waist circumference and level of markers of non-specific inflammation: highly sensitive C-reactive protein and tumor necrosis factor-α.
THE RESULTS OF SCANNING ELECTRONIC MICROSCOPY OF ULTRA-THIN ENDOKERATOTRANSPLANT FORMED BY FEMTOSECOND LASER ON PART OF ENDOTHELIUM
Authors: Oganesyan Oganes G. , Yakovleva S. S , Baranchikov A. E , Ivanov V. K
Published: April 2019

Nowadays, the posterior keratoplasty is an operation of original choice in treatment of patients with pathology of endothelium. The purpose of study. To analyze, in ex vivo conditions and using scanning electronic microscopy technique, the quality of stromal surface of transplant formed by femtosecond laser on part of endothelium (invertedly). Material and methods. The series of scanning electronic microscopy of surface of stroma of cornea after femtodissection were applied to investigate effect of parameters of femtodissection and also impact of viscoelastic on quality of stromal surface. Six pairs of eyes of donors unfitted to keratoplasty were used. To form a transplant the femtosecond laser platform LDV Z6 (Ziemer, Switzerland) was applied.
THE LICANTHROPY: THE PSYCHO-NEUROLOGICAL AND SOMATIC ASPECTS
Authors: Damulin I. V , Sivolap Yu. P
Published: April 2019

The review article considers syndrome of lycanthropy when patient considers oneself as an animal (more often as a wolf). The clinical picture of lycanthropy is typical for such mental diseases as schizophrenia, bipolar disorder, psychotic depression. The lycanthropy can be developed against the background of dementia and epilepsy. In number of cases, concept of lycanthropy, especially in the past, was related with expressed hirsutism or severe congenital porphyria and also with diseases manifesting expressed changes of face (leprosy, syphilitic gumma). The lycanthropy can be developed after intake of psycho-active substances, in case of intoxication with vegetable alkaloid or against the background of alcohol abuse. Therefore, it is necessary to carry put a corresponding examination of patients to exclude neurological or somatic cause of this syndrome. The anti-psychotic medications, antidepressants, electroconvulsive therapy and psychotherapy are applied for treatment in case when lycanthropy is caused by mental pathology.
THE LIFE AND BIOGRAPHY OF THE LEGENDARY PROFESSOR V.F. VOYNO-YASENETSKY, THE ARCHBISHOP AND SURGEON (TO THE HUNDRED FORTIETH ANNIVERSARY: 1877-1961)
Authors: Morgoshia Temuri Sh.
Published: April 2019

V.F. Voyno-Yasenetsky, after receiving diploma of physician, improved in the clinic of P.I. Diakov, and in the Institute of topographic anatomy and operative surgery at F.A. Rein. In 1905-1914 V.F. Voyno-Yasenetsky worked as Zemstvo physician in hospitals of the Simbirsk, Kursk and Vladimir gubernias and during the First world War he was a surgeon and chief physician of infirmary for the wounded. In 1915 V.F. Voyno-Yasenetsky published in St. Petersburg the book «The regional anesthesia» with one's own illustrations. In 1919 he defended the doctoral dissertation about regional anesthesia in the Moscow University. The dissertation was awarded by the Warsaw University. In 1917-1930 he worked as a surgeon of municipal hospital in Tashkent and from March 1917 he became the chief physician. From 1920 V.F. Voyno-Yasenetsky is a professor of the Chair of Topographic Anatomy and Operative Surgery in the Turkestan University. His input into practical surgery is analyzed. The operation of removal of sacroiliac symphysis with rear part of wing of ilium affected by purulent process belongs to him (resection of pelvis according Voyno-Yasenetsky). The original mode of closure of wound positioned at periphery of diaphragm also belong to him (Voyno-Yasenetsky mode ). He proposed original mode of mobilization of spleen and ligation of vessels under splenectomy (Voyno-Yasenetsky mode). V.F. Voyno-Yasenetsky described such important for surgeons topographic anatomic reference points as a projection of sciatic nerve on skin of a rear surface of thigh (Voyno-Yasenetsky line) and area of outlet of sciatic nerve from under gluteal fold (Voyno-Yasenetsky point). In 1946, V.F. Voyno-Yasenetsky was honored with the Stalin Award Degree I for books «The essays of contaminated surgery» (1943) and «The late resections under infected gunshot wounds of joints» (1944).
THE DEVELOPMENT AND IMPLEMENTATION OF THE MOST OPTIMAL SYSTEM OF INTERACTION OF A LARGE MULTI-FIELD CHILDREN HOSPITAL WITH INSURANCE COMPANIES CONCERNING PROGRAMS OF VOLUNTARY MEDICAL INSURANCE
Authors: Polunina N. V , Osmanov I. M , Mironova A. K , Polunin Valery S.
Published: April 2019

Actuality of the study. Nowadays, in the Russian Federation, medical organizations have, independently of organizational legal form, a right to provide paid services both to population and legal persons. The purpose is to develop and implement an optimal system of interaction of large multi-type children hospital with insurance organizations. Materials and methods. The process of development of organization of medical services provision was studied within the frameworks of voluntary medical insurance during 2011-2017 in the Z.A. Bashliaeva children municipal clinical hospital. Results. During 2011-2016 an increasing of annual amount of funds received from medical services provision according voluntary medical insurance programs up to 14 times. The experience of optimal interaction of medical organization with insurance companies according voluntary medical insurance programs. Conclusion. It is appropriate to pay a special attention to effective interaction between medical organization and insurance company, to algorithm of functioning of medical organization during qualitative medical care support of children population in conditions of multi-type hospital complex.
DOES THE SCALE SAME-TT2R2 FUNCTIONS IN REAL CLINICAL PRACTICE?
Authors: Minushkina Larisa O. , Azizova A. G , Voskresenskaya T. V
Published: April 2019

◆The possibilities of anticoagulant therapy in patients with atrial fibrillation significantly increased during last years. The warfarin therapy can be ineffective in those patients who can't neatly follow regimen of treatment, to control international normalized ratio in blood or international normalized ratio is retained with difficulty on recommended level. The scale SAMe-TT2R2 is considered as appropriate one to apply for more exact preliminary evaluation of possibility of achieving anticoagulation under application of antagonists of vitamin K. The purpose of study was to validate scale SAMe-TT2R2 on the group of observed out-patients in a real clinical practice. The study included 55 patients receiving warfarin because of non-valvular atrial fibrillation. In 30 patients (54.5%) a paroxysmal atrial fibrillation was observed and in 25 patients (45.5%) - permanent form of this disease. The examined group included 14 females and 41 males with average age of 71,3 ± 7,52 years. The patients receiving warfarin were in target range of international normalized ratio (2-3) 64,3 ± 12,91%of intake time. The percentage of patients residing within target range of international normalized ratio 60% of time and more comprised 58.9%. In average, patients taking during a year warfarin as anticoagulant controlled international normalized ratio 9,6 ± 0,41 times. In the examined group, 30 patients had according scale SAMe-TT2R2 0-1 point and 25 patients - 2 and more points. The scale had low diagnostic value (the square under ROC-curve 0.582), low sensitivity model 0.429 and moderate specificity 0.758 in relation to prediction of residence time in the target range of international normalized ratio 60%. For the value TTR 60% the diagnostic value turned out higher - 0.619 (sensitivity 0.547, specificity 0.789).
THE HEMOFILTRATION AT INFUSION THERAPY OF SEVERE ACUTE PANCREATITIS
Authors: Ganert Andrey N. , Kokorev E. V , Zhbannikov P. S , Zabusov A. V
Published: April 2019

The 64 patients with severe acute pancreatitis at admission in hospital arterial hypertension, low venous saturation of oxygen (ScvO2), hyperlactemia, oligoanuria and hypercreatininemia were observed. This occurrence became an indication for infusion therapy to recover and optimize hemodynamics. After 6 hours of therapy, 30 patients were lacked increasing of diuresis related to infusion load and hypercreatininemia increased and also significantly increased positive fluid balance s compared to other patients. These 30 patients were additionally applied hemofiltration during 66 hours. The infusion therapy was characterized by difficulty of restoration and optimization of hemodynamic, large volumes of infusion mediums та frequent application of sympathomimetics. In patients without hemofiltration a significant increasing of cumulative fluid balance was added. The hemofiltration permitted to normalize diuresis, to prevent surplus cumulation of fluid and to support blood circulation at the optimal level.
THE PROBLEMS OF ANGIOGENESIS IN THE EYE OF PREMATURE CHILD
Authors: Sidorenko E. I
Published: April 2019

The purpose of study is to investigate pathogenesis of the first pre-clinical stage of retinopathy in premature children. Materials and methods. The sampling for examination included 642 premature born children. At the moment of birth, the gestation age was uз to 30 weeks, body mass up to 1500 g (very low body mass). The study included: indirect ophthalmoscopy; digital retinoscopy using wild-field retinal pediatric camera; calibermetry of retinal vessels. The intravital analysis of biochemical composition of vitreous body in 74 children with retinopathy and 45 animals (young rabbits chinchilla). The intra-vitreous injection of inhibitors VEGF was applied to more than 300 premature born children. The results. The retinopathy of premature born children is a leading cause of blindness. The article is devoted to mainly studying pathogenesis of only pre-clinical phase I of retinopathy of premature born children that is factually explored insufficiently. It is established that pathological angiogenesis of retina triggers an area of retina with vessels that stimulates functioning of system of struggle with hyper oxygenation and delays a normal development of angiogenesis. The immature auto-regulation of vessels of retina inadequately reacts to oxygen causing expressed angiospasm and developed circulatory disorders in vascularized retina aggravating total hypoxia. These processes delay angiogenesis almost for a month. The hypoxia-induced factors HIF1.2,3 began with significant delay both to be cumulated and to stimulate production of vascular endothelial growth factor. Conclusion. The study of pathogenesis phase I of retinopathy of premature born children open opportunity to effect pathogenic sections of disease and to prevent blindness and visual impairedness in premature born children.
THE COMPARATIVE ASPECTS OF TWO MODIFICATIONS OF GASTRIC RESECTION ACCORDING T. BILLROTH TECHNIQUE IN ONCOLOGIC PRACTICE
Authors: Morgoshia Temuri Sh.
Published: April 2019

The surgical intervention implying total ablation of tumor, continues to be the only method giving hope for recovery of patient despite a significant number of combined and complex methods of treatment of the given disease. However, many positions of the given conception underwent cardinal changes. Nowadays, most of authors recommend after gastric resection to restore to the extent possible natural anatomic relationships that provides best functional results. At the same time, certain researchers give preference to Billroth-II mode and at that some of them are devoted opponents of gastric resection by Billroth-I mode in case of cancer. This opinion is based on supposition that gastric resection by Billroth-II mode provides in greater extent radicalism in case of treatment of malignant neoplasms of given localization. The main factor restraining application of this most physiological operation is established opinion alleging its oncologic non-efficacy. The thesis is substantiated that intervention into modification of operation according Billroth method does not result in increasing of number of post-operative complications and that there is no differences also in distant results of surgical treatment of gastric cancer in case of application of both modes of restoration of continuity of digestive tract after sub-total distal resection. At the same time, quality of life of patients becomes better after reconstruction of digestive tract using gastroduodenal anastomosis. Most of researchers, studying indications to sub-total gastric resection using method Billroth-I, assume that it is reasonable to apply this particular mode of restoration of continuity of gastrointestinal tract only in case of early cancer, its exophytic forms (stage I and II) located in area of stomach angle or its low one third of its body and absence of metastases into regional lymphatic nodes.
THE EVALUATION OF IMMUNOGENIC POTENTIAL OF VARIOUS MEDICATIONS OF INSULIN
Authors: Philippova Anastasiya V. , Chzhao V. , Kolbin A. S
Published: April 2019

The article presents a review of publications implemented with the purpose to characterize immunogenic potential of medications of insulin: from preparations of animal origin to modern genetically engineered products. The review is presented concerning regulative requirements regulating control of insulin products safety. It is established that during evaluation of safety of insulin products the main attention is focused on issues of immunogenicity. The analysis of publications from open access in information database MEDLINE (Pubmed) was carried out, permitting to characterize immunogenic potential of insulin preparations. On balance, the review included 17 articles according the results of selection. It is established that information about immunogenic potential of insulin products is contradictory enough that can be determined by both characteristics of studies and technological particularities of production of medicinal insulin products. The modern preparations of analogs of insulin are in general comparative by their safety characteristics with medicinal preparations of human genetically engineered insulin. Among analogs of insulin the most immunogenic potential is specific to aspart and glargin. The cases of development of cross-reactive antibodies between various medicinal preparations of insulin are observed.
COMPARATIVE EVALUATION OF BONE TISSUE REGENERATION WITH LIMITED DEFECTS OF THE PARIETAL BONE (EXPERIMENTAL STUDY ON ANIMAL MODELS)
Authors: Khelminskaya Natalia M. , Ettinger A. P , Kravets V. I , Polivoda M. D , Goncharova A. V , Krasnov N. M
Published: April 2019

At today, in practice of dental surgeons and maxillofacial surgeons offten used synthetic osteoplastic material which contain in its constitution hydroxyapatite,tricalcium phosphate, collagen, glycosaminoglycans (GAG), chondroitin sulfate, calcium sulfate and phosphate, antibacterial and anti-inflammatory drugs in various combinations and proportions. The bone replacement materialsserve as a framework on the basis of which in afterwards mature bone tissue forming. It should be noted that it is not possible to achieve full recovery of the lost bone tissue, in most cases unfinished regeneration is observed. In the presented work was made a comparative evaluationof the effectivness usage osteoplastic materials for replacement of limited defects of bone tissue in animal experiments.
COURSE AND OUTCOME OF PREGNANCY, OBSTETRIC TACTICS BY PRETERM RUPTURE OF MEMBRANES AT THE TERM OF 24-32 WEEKS
Authors: Dudareva Yulia A. , Guryeva V. A , Filchakova O. N
Published: April 2019

The birth of premature children is the cause of the increase in morbidity and perinatal mortality in the country, that is why it is necessary to carry out not only prognosis of premature births but also to correctly determine the tactics of managing patients with premature rupture of membranes. The objective of the study was to evaluate the course of pregnancy, perinatal outcomes, depending on the chosen tactics of managing women with premature discharge of amniotic fluid in the period of 24-32 weeks of pregnancy. Materials and methods: 46 patients were included in this study, 26 of them were the main group with premature rupture of membranes at a gestation period of 24-32 weeks, long anhydrous period (more than 48 hours), and 20 patients were included into the control group. The main criterion for inclusion in the control group was a spontaneous active onset of labor at a gestation period of 24-32 weeks, with an anhydrous period of less than 12 hours. Results: Patients of both groups were comparable in age, frequency of extragenital and gynecological pathology, main characteristics of menstrual function, parity and outcomes of pregnancies. In the presence of certain conditions in the main group, it was possible to apply expectant management tactics, which, on average, prolonged the pregnancy by 12.0 ± 2.3 days, which in 30.8% of cases was accompanied by the development of chorionamnionitis (p = 0.020), without interrelation with duration of anhydrous period and frequency of postpartum purulent-septic complications. It was found that perinatal outcomes, weight and condition of newborns at birth were much better in women in the main group. Conclusion: The reasonably chosen expectant management strategy for women with premature rupture of membranes at the gestational period of 24-32 weeks, subject to certain conditions, will improve perinatal outcomes without significantly increasing the incidence of infectious and inflammatory processes in the mother and newborn.
THE POSSIBILITY OF APPLICATIONS OF MODERN METHODS OF BRONCHODILATOR THERAPY IN PATIENTS WITH DIFFERENT FORMS OF PULMONARY TUBERCULOSIS
Authors: Kuklina Galina M. , Shmelev E. I
Published: April 2019

The paper presents the results of the possibility of applications of modern methods of bronchodilator therapy in patients with different forms of pulmonary tuberculosis, combined with COPD and asthma. On a large contingent of patients, the clinical efficacy of bronchodilator therapy has been demonstrated. In this case, the positive effect of bronchodilator therapy was distributed in three main areas: the general condition of patients, the course of tuberculosis and the course of COPD and asthma. In all three directions, positive results were obtained: the general condition of patients improved, the terms of bacilli were reduced and the rate of regression of the tuberculosis process increased, and the effectiveness of control of COPD and asthma increased. These data are a reliable indicator of the feasibility of cooperation between phthisiology and pulmonology.
CHOICE OF METHODS OF ANESTHESIA FOR SURGICAL OPERATIONS AND POSTOPERATIVE PAIN MANAGEMENT IN PATIENTS WITH SKIN AND SOFT TISSUE INFECTIONS
Authors: Rhalib Sophia M. , Sviridov S. V , Vedenina I. V
Published: April 2019

The article presents a review of the literature highlighting to the choice of methods of anesthesia and treatment of postoperative pain syndrome in patients with skin and soft tissue infections (SSTI). Taking into account the particularity of patients with SSTI, who need multiple operations and long hospitalization, the choice of the method of anesthesia directly affects the quality of the patient’s postoperative management, contributes to the prevention of chronic pain, which facilitates the earlier activation of the patient.
DRAINING AUTO VALVE LIMBOSCLERECTOMY IN POSTTRAUMATIC GLAUCOMA TREATMENT
Authors: Lapochkin Andrey V. , Lapochkin D. V , Zakharova D. A , Ovsyanko A. A , Spirin D. V
Published: April 2019

The aim of the current article is to report the case of a patient with posttraumatic glaucoma who underwent a successful a draining auto valve limbosclerectomy (DALS) 6 months ago. A 65-year-old patient admitted on April 2017 with history of blunt left eye trauma. The diagnosis of severe eye contusion, Ectopia lentis and ocular hypertension was made. A subtotal vitrectomy, lensectomy and iris fixation of posterior chamber intraocular lense were performed the next day. A laser trabeculoplasty was performed 10 days after surgery for lowering IOP. During a follow-up examination, the patient was found high IOP in the left eye despite maximum IOP-lowering topical treatment. A draining auto valve limbosclerectomy (DALS) was performed in the left eye. The reduction in IOP has subsequently been maintained over six months of follow-up. This patient’s experience is a single case, yet it contributes to the evidence that a draining auto valve limbosclerectomy (DALS) may be high efficient in posttraumatic glaucoma treatment.
CHANGES OF ANGIOGENIC FACTORS AND MARKERS OF ENDOTHELIAL DYSFUNCTION IN CHILDREN AND ADOLESCENTS OF WILSON-KONOVALOV DISEASE
Authors: Batyrova Anna S. , Vasilyeva E. M , Bakanov M. I , Surkov A. N
Published: April 2019

Although angiogenesis is an integral part of tumor progression, it has also been observed in different inflammatory, fibrotic, and ischemic diseases. Angiogenesis is a multifactorial process and its changes bring essential information about the status of complex pathology. Aim: evaluate the role of angiogenesis and endothelial dysfunction factors in Wilson-Konovalov disease (WKD) in children and adolescents. Methods: 19 children and adolescents with WKD were included in the study. VEGF-A, angiotensin (ANG), soluble receptors of VEGF-A (sVEGF-R1 и sVEGF-R2) and trombomodulin have been investigated in serum by enzyme immunoassay using special kits (BCM Diagnostics, USA). Other endothelial dysfunction markers as von Willebrand factor (vWf) was determined in blood plasma by immunoturbidimetry (Siemens, Germany), plasminogen (PLG) was investigated due to extended coagulation. Results: it was founded marked decreasing of VEGF-A and increasing concentration of sVEGF-R1, sVEGF-R2 in blood plasma of WKD children and adolescence by comparison of reference group. ANG did not change. Comparing the ratio of levels VEGF-A+ANG/sVEGF-R1+sVEGF-R2 (in children with WKD 16,7±1,9 and in reference group 23,0±1,6, р
ISOLATED SYNOVIAL TUBERCULOSIS OF THE KNEE JOINT
Authors: Khomenko Vladimir A. , Semenova L. A , Shekhter A. B , Lyalina V. V , Savitsky P. P
Published: April 2019

We present a clinical observation of a patient with tuberculosis of the synovium without X-ray signs of tuberculosis of the lungs and bone tissue which confirms possibility of an isolated tuberculosis synovitis. The case demonstrates the necessity of synovial fluid assessment for early diagnostics of tuberculous inflammation in the joint. Diagnostic arthroscopy and synovial biopsy reveal specific changes. Early diagnostics of isolated tuberculosis synovitis can contribute to the timely treatment and prevent the adjacent bones involvement.
Stimulating factor in the provision of tax credits in Slovakia
Authors: Sedliacikova Mariana , Vavrova Katarina , Badura Peter , Kalusova Lenka
Published: April 2019

The aim of this paper is to evaluate the issue of tax incentives in Slovak republic. Characteristics of particular types of the tax incentives used in tax practice and impact of tax incentives on the income tax used in Slovakia were analysed. All approval processes and terms of taking incentives were solved through the model case study. Based on the analysis of primary and secondary sources and practical experiences, it was elaborated a SWOT analysis of the strengths and weaknesses of fiscal incentives in Slovakia. Keywords: Tax incentives, Slovak republic, income tax.
The Disability Community Ain’t What It Used to Be: Implications of Emerging Disabilities for Rehabilitation Research, Policy, and Education
Authors: Rumrill Phillip D. , Koch Lynn C. , Bishop Malachy L.
Published: April 2019

Background

This article introduces the concept of emerging disabilities as it applies to rehabilitation counseling practice, research, policy, and education.

Definition

Emerging disabilities are those that are either new to medical science or becoming more prevalent in specified subpopulations of people. A case study of a person with an emerging disability (diabetes mellitus) is presented.

Implications

Implications of emerging disabilities for the field of rehabilitation counseling are discussed.
Needle and Syringe Programs in Rural Areas: Addressing the Intravenous Drug Use Epidemic
Authors: Kim Byung Jin , Harley Debra A.
Published: April 2019

Background

Opioid use has reached epidemic proportions in rural communities in the United States and injection of drugs is commonly used. As a result of shared or reusing needles and syringes, the risk for contracting blood-borne diseases is significantly increased. Rural areas face many social and attitudinal barriers regarding syringe exchange programs (SEPs).

Objective

This article describes national trends for drug injection problems in rural areas and discusses effectiveness of needle and SEPs as a harm reduction healthcare policy. Ethical and practical considerations in the implementation of SEPs are also presented.

Method

The rehabilitation literature was reviewed on trends in substance abuse and intravenous (IV) drug use in rural areas to identify the status and need for SEPs to address risk factors of infectious diseases resulting from needle sharing and reusing of needles.

Findings

IV drug use in rural communities has reached epidemic proportions with resulting dramatic increases in hepatitis C and B and incidence of HIV. Yet, many rural communities continue to object to the implementation of SEPs due to fears that such programs will increase drug use and crime in the community.

Conclusion

IV drug use is a critical public health issue for users and non-IV users in rural communities, and is increasingly becoming an issue about which rural rehabilitation counselors will need to be informed. For the sake of public health, SEPs should be recognized as an economical, ethical, and effective factor in the larger response to the epidemic of IV drug use in rural America.
GEOMORFOLOGIA GRANÍTICA DO MACIÇO DE URUBURETAMA, CEARÁ, BRASIL
Authors: Lima Danielle Lopes de Sousa , Bastos Frederico de Holanda , Cordeiro Abner Monteiro Nunes , Maia Rubson Pinheiro
Published: April 2019

O Maciço de Uruburetama, localizado na porção norte do Estado do Ceará, apresenta uma forte relação estrutural com seu modelado, o que se evidencia na exposição de macroformas e microformas graníticas, cuja origem e desenvolvimento estão associadas, predominantemente, ao intemperismo seletivo, tanto em subsuperfície como na superfície topográfica, condicionado pelas características do substrato, seguida da remoção do manto de alteração. Dessa forma, o presente estudo classifica e descreve as diferentes feições geomorfológicas com granito aflorante na área de estudo. A metodologia utilizada teve como base pesquisa bibliográfica referente às teorias de evolução geomorfológica, com ênfase na teoria da etchplanação; revisão bibliográfica sobre a gênese e evolução de relevos graníticos; trabalhos de campo e levantamentos cartográficos. As principais formas de relevos graníticas encontradas podem ser divididas em macroformas associadas ao desenvolvimento de inselbergs e bornhardts, e microformas associadas com blocos graníticos (boulders, caos de blocos, nubbins, tors e castle koppies), com formas de dissolução (tafoni, alvéolos, karren, gnammas e flared slopes) ou de fraturamento (split rock e polygonal cracking). Tais feições exibem grande singularidade geomorfológica e constituem peças fundamentais na compreensão da evolução paleoclimática e geomorfológica regional.
ESTIMATIVA E MAPEAMENTO DA EROSÃO BRUTA NA BACIA HIDROGRÁFICA DO RIO SERIDÓ, BRASIL
Authors: Rabelo Davi Rodrigues , De Araújo José Carlos
Published: April 2019

Os sertões nordestinos sofrem as consequências da intensificaçãodos processos morfodinâmicos superficiais através da erosão, causada por uso intensivo e inadequado do solo. Tais problemas geram consequências para a relação entre a Sociedade e a Natureza. De fato, a erosão e o assoreamento, causam, entre outros, impactos sócio-ambientais e econômicos, tais como o desgaste do perfil de solo, a diminuição da produtividade agrícola, a redução da capacidade de armazenamento de rios e reservatórios, assim como a diminuição da disponibilidade hídrica. A presente pesquisa buscou estimar a erosão bruta da bacia hidrográfica do Rio Seridó (RN-PB, 10 mil km²) afim de entender como se distribui espacialmente a erosão em toda extensão da bacia. Foram utilizados dados primários e secundários na produção de mapas temáticos, revisão teórico-metodológica do objeto, utilização de imagens (sensoriamento remoto), métodos geoestatísticos, realização de trabalho de campo e modelagem sedimentológica. Para estimativa da erosão bruta foi utilizada a Equação Universal de Perda de Solo (EUPS) para o recorte temporal de 1992 até 2015. Com isso, foi possível interpolar espacialmente as variáveis da EUPS de interesse para toda a bacia. Foram gerados mapas de erosividade de chuva, erodibilidade do solo, fator topográfico e fator de uso e cobertura do solo. Essas informações permitiram a parametrização da EUPS, que sintetiza a erosão bruta na bacia. A erosão bruta média da bacia (1992-2015) foi de 29 ton.ha-1.ano-1, porém, em alguns pontos críticos, a erosão bruta superou 100 ton.ha-1.ano-1. A metodologia aplicada permitiu, portanto, uma avaliação temporal e espacial da erosão bruta na bacia.
DIVERSIDADE MORFOLÓGICA DAS DUNAS FRONTAIS NO LITORAL NORTE DO RIO GRANDE DO SUL, BRASIL
Authors: Vianna Humberto Dias , Calliari Lauro Julio
Published: April 2019

A formação do sistema praia-duna está relacionada a morfodinâmica praial, sedimentologia e orientação do vento predominante em relação à linha de costa. Esse trabalho teve o objetivo de identificar as variáveis morfológicas e sedimentológicas responsáveis pela diversidade do sistema praia-duna frontal no litoral norte do Rio Grande do Sul (RS) e descrever a morfologia das dunas frontais. Variáveis morfológicas como a altura das dunas frontais, azimute da linha de costa, largura e declividade da praia subaérea foram obtidas das referências. O percentual de cobertura vegetal das dunas frontais foi obtido com o uso de modelos digitais de superfície, produzidos com laser scanning (LIDAR), e imagens de satélite de alta resolução, classificadas pela técnica de máxima verossimilhança. Coletas de sedimentos superficiais foram efetuadas nas dunas frontais e praia subaérea para determinar os percentuais de areias médias. As variáveis morfológicas e sedimentológicas foram analisadas pelas técnicas estatísticas clustering e componentes principais. O percentual de cobertura vegetal médio das dunas frontais é de 65,2%. Nos balneários da região há predominância de areias finas quartzosas bem a muito bem classificadas. O percentual de areia média é de 6,9% (dunas frontais) e 7,1% (praia subaérea). Três grupos de balneários foram gerados nas análises estatísticas. O grupo 1 possui o menor percentual de areia média na praia subaérea (4,3%), dunas frontais de menor altura (3,5 m), menor percentual de cobertura vegetal (52,2%) e maior azimute médio da linha de costa (32,8°). As dunas frontais são de estágios erosivos avançados, possuem pequena altura e baixa cobertura vegetal. O grupo 2 apresenta o maior percentual de areia média nas dunas (8,3%), menor largura média da praia subaérea (48,0 m) e dunas frontais de 4,1 m de altura média. O grupo 3 detém o mais elevado percentual de areia média da praia subaérea (7,6%), maior percentual de cobertura vegetal das dunas frontais (73,4%), mais extensa praia subaérea e dunas frontais com 3,9m de altura média. O mesmo grupo apresenta o menor percentual de areia média nas dunas (5,6%) e menor azimute médio da linha de costa (25,1°). As dunas frontais dos grupos 2 e 3 estão em estágios erosivos moderados, a topografia hummocky é frequente, devido a ação de blowouts e sangradouros que seccionam as dunas frontais. A análise de componentes principais demonstrou que não há correlação entre as variáveis morfológicas e sedimentológicas. As únicas variáveis correlacionadas negativamente são altura das dunas frontais e azimute de linha de costa. Na região estudada, a orientação da linha de costa favorece o transporte sedimentar, pois permite que o vento predominante incida em um ângulo próximo a 45° na costa. Alguns trechos estudados não se agruparam, pois possuem características únicas como: dunas frontais de maior altura e mais bem vegetadas, azimute da linha de costa próximo a 40°, e altos percentuais de areias médias nos ambientes estudados.
The History and Evolution of the Southeastern Conference for Public Administration
Authors: Berlan David , Shen Ruowen , Klay William Earle
Published: April 2019

The Southeastern Conference for Public Administration (SECoPA) began in 1969 in the wake of reapportionment and desegregation. The founders of SECoPA sought to promote the emergence of a new South, one that would be both dynamic and inclusive, by promoting the practice and study of public administration throughout the region. In the decades since, SECoPA has continued to host annual conferences serving the region. Through coding and analysis of annual conference programs, and using the lens of new institutionalism, this article explores SECoPA’s history and fidelity to its founding mission. The annual conferences have been responsive to concerns of public administration scholars in the region, but drastic declines in practitioner participation mirror broader trends in the profession.
ANALYSIS OF THE USE OF SPOILER ONE LEVEL AND TWO LEVELS IN CONDITIONS OF STEADY AGAINST THE DRAG AND LIFT COEFFICIENTS ON A SEDAN TYPE CAR BY USING CFD (COMPUTATIONAL FLUID DYNAMIC)
Authors: Frihdianto Fajar , Wardani Nyeyep Sri , Widiastuti Indah
Published: April 2019

This research was simulation analyzing the condition of steady flow in around of body car made and analized computly using CFD program (Computational Fluid Dynamic). The model used was Sedan car designed with different rear end body by adding spoiler. Analyzing in this research was done by using Software 18.2–CFD Student Version. Design of the three models were compared to find out the difference in magnitude of Coefficient of Drag, Coefficient of Lift, pressure distribution, velocity distribution, and behavioral character of flow around the rear end of car in the condition of steady flow. Model was made in appropriate scale with model of Honda city 2008 sedan car. Observation was made to look at the behavior of fluida flows both in front and back the car in different fluid speed ranges in steady condition.

The simulation results obtained from packet CFD on each condition were; model without spoiler, model with 1 level spoiler, and model with 2 level spoiler. Where this simulation showed that CD and CL were decrease. One of the example was at speed 40km/hour obtained the coefficient of drag (CD) of 0.31061, 0.28603, and 0.2054, it proved that 1 level spoiler could reduce the value of drag coefficient about 7.9135% of the sedan car without spoiler, while the car with 2 level spoiler could reduce the value of drag coefficient about 33.8592% without spoiler. For the coefficient of lift (CL) on each model was -0.38487, -0.54624, and -0.62097 proved that spoiler 1 level could reduce the value of lift coeffient about 41.92845% of the sedan car without spoiler, while the car with 2 level spoiler could reduce the value of lift coefficient about 61.35984% without spoiler. On the result of pressure distrubution and relative velocity give little affect to the upper and lower surface where this was indicated by almost no color difference contours. Then, if it was indicated from streamline and the formation of vortex, there was a significant difference so that it was very influential on the size of CD and CL occoured. By changing geometric proved that the spoiler car 1 and 2 level were more aerodynamic than the car without spoiler.