bluuebunny/crossref_metadata_2025 huggingface dataset:
ДИАГНОСТИКА СТЕКЛОПЛАСТИКОВОГО КОМПОЗИТА, ИСПОЛЬЗУЕМОГО ДЛЯ ИЗГОТОВЛЕНИЯ КОРПУСА ГЕОФИЗИЧЕСКОГО ПРИБОРА ПО НЕУПРУГОСТИ
Authors: Дудкевич  Инна Алексеевна Дудкевич  Инна Алексеевна , Ананьева Елена Сергеевна
Published: April 2024

Повышение точности получаемых данных, стабильности результатов исследования скважин, улучшение прочностных свойств радиопрозрачного корпуса, и как следствие, повышение ресурса геофизического прибора невозможно без диагностики свойств материала корпуса и оценки уровней нагрузок, способных привести материал к потере несущей способности. Исследовано влияние разных схем циклического нагружения на форму и размеры петли неупругости при испытаниях кольцевых образцов из стеклопластика (0 º‒90 º), изготовленных методом косослойно-продольно-поперечной намотки стеклянного волокна на основе алюмоборосиликатного и магнийалюмоборосиликатного стекла. В результате исследования влияния схем нагружения было показано изменение формы и петли неупругости и переход от релаксационного типа неупругости к неупругости гистерезисного типа из-за накопления остаточных деформаций при изменении угла нагружения с 30 º на 45 º и увеличении амплитуды нагрузки. Результаты разрушения образцов при схемах нагружения аналогичны условиям нагружения в эксплуатации и могут быть использованы для оценки процесса разрушения.
РАЗРАБОТКА СПОСОБА ПОЛУЧЕНИЯ ДИОКСИДА ТИТАНА, ЛЕГИРОВАННОГО МЕДЬЮ, ДЛЯ СОЗДАНИЯ МЕМРИСТОРНЫХ ЭЛЕМЕНТОВ ПАМЯТИ
Authors: Уразбеков Артур Еркынович Уразбеков Артур Еркынович , Троян  Павел Ефимович Троян  Павел Ефимович , Сахаров Юрий Владимирович Сахаров Юрий Владимирович
Published: April 2024

С каждым годом в мире количество цифровой информации нелинейно возрастает. Эта тенденция делает необходимым поиск новых современных элементов памяти, для чего требуется решение задач материаловедения, в частности отработки технологии осаждения тонких пленок диэлектриков, обладающих принципиально новыми свойствами, обусловленными электромиграцией в них кислородных вакансий или атомов металла. В статье представлены результаты разработки процесса осаждения и исследования пленок диоксида титана модифицированного (легированного) медью для создания на этой базе запоминающих устройств (мемристоров). Построены вольт-амперные зависимости. Показан эффект резистивного переключения. Обнаружено, что из предложенных способов получения диоксида титана приводит к существенному улучшению основных мемристивных характеристик в сравнении запоминающими устройствами на основе диоксида титана без модификации медью. В частности, показано, что использование данных пленок в структуре мемристора позволяет увеличить отношение состояния с высоким электрическим сопротивлением к состоянию с низким электрическим сопротивлением более чем в 102 раз.
Application of a complex of biologically active substances of Аronia melanocarpa in parapharmaceutical phytofilms
Authors:   Vyatka State University, Kozvonin V. A. ,   Kirov State Medical University, Tovstik E. V. ,   Vyatka State University, Tupitsyn V. K. ,   Kirov State Medical University, Votintseva S. A. ,   Vyatka State University
Published: April 2024

The article presents the results of using non-pharmacopoeial plant raw material – dried leaves of the perennial cultivated chokeberry shrub Aronia melanocarpa (Michx.) Elliott. as a source of substances with anti-inflammatory and wound-healing effect. The development of a parapharmaceutical phytofilm based on a complex of biologically active substances from A. melanocarpa is described. The results of preclinical evaluation of the developed phytofilm in an experimental model of skin wound on outbred white rats are presented. The developed phytofilm is environmentally safe compared to synthetic analogues which production is accompanied by a negative environmental impact. Substances with antioxidant properties which can play the role of a medicinal base were found in the composition of aqueous extracts from chokeberry leaves: polyphenols – 7.4±0.7, tannins – 4.6±0.5 mg/cm3. The safety of using A. melanocarpa leaves as raw material for phytofilm has been confirmed in heavy metal tests. The composition and film-forming ability of chokeberry leaves aqueous extract, including polyvinyl alcohol (098-15(G)) (6%), food grade gelatin P-11 (0.5%), glycerin (GOST 6259-75) (0.4%), colloidal silver solution 200 mg/dm3 (1%) has been established. A. melanocarpa leaves extract application to the film-forming solution increases the final vapor permeability by 48% and solubility by 14%. The model experiment shows the effect of using the created phytofilm in the reparation of linear wounds, manifested as significant decrease in their length by 30% by the fifth day, by 25% by the seventh day compared with the control, as well as normalization of the skin histological structure by the tenth day.
Zoning factors and their influence on the lakes’ zooplankton in the Middle Volga Region (Russia)
Authors:   Kazan Federal University, Derevenskaya O. Yu. , Mingazova N. M. ,   Kazan Federal University, Unkovskaya E. N. ,   Volga-Kama State Nature Biosphere Reserve
Published: April 2024

We analyzed the results of studies of 176 different types of lakes in the Middle Volga region (Russia). The impact of various environmental factors (morphometric parameters of lakes, physical and chemical indicators of water) on the lakes’ zooplankton communities of two landscape-geographical zones (forest and forest-steppe) was studied. The aim of the work was to identify the biodiversity of pelagic zooplankton and to assess the role of environmental factors in the development of zooplankton communities. Statistical studies included the calculation of the Spearman and Pearson correlation coefficients, data analysis using linear and logistic regression methods. We identify 230 species of zooplankton, including Rotifera – 107 (45.6%), Cladocera – 76 (33.6%), Copepoda – 47 (20.8%). Forest lakes show more species in the sample and higher quantitative indices compared to the forest-steppe lakes. The values of these indicators are determined by a complex of factors, the most important of which are the morphometric parameters of the lakes, the content of mineral nitrogen, oxygen, water mineralization and its determining ions. The depth of the reservoir can increase in the number of species in the sample or decrease them. Zooplankton quantification decreases as maximum depth increases. In deep-water lakes they are usually lower than in wellwarmed high-trophic and shallow ones. High mineralization and higher content of nutrients reduce the number of species in the sample and quantitative indicators of zooplankton. The increase in mineral nitrogen concentration and average ranking index is negatively related to zooplankton abundance, which is due to the occurrence of negative effects associated with anthropogenic eutrophication. Local conditions determine the composition and structure of zooplankton communities within the landscape-climatic zones, which determine the ionic composition of water and the concentration of major ions.
DESIGN OF REINFORCED CONCRETE STRUCTURE WITH ORDINARY MOMENT FRAME IN LOW SEISMIC REGION (CASE STUDY: MIDRISE SHOPPING BUILDING IN SINGKAWANG CITY)
Authors: Zulshaec Yongga , Herwani Herwani , Yusuf Muhammad
Published: April 2024

This paper focuses on the design of a reinforced concrete structure for an eight-story shopping building in Singkawang City, located in a low to moderate seismic area. The study integrates relevant design considerations in response to the region's seismic conditions. Through structural analysis, the building is categorized as seismic design category B due to moderate seismic risk, leading to the selection of an ordinary moment-resisting frame system compliant with SNI 1726:2019. Emphasis is placed on the importance of using such a system to enhance ductility and prevent brittleness during earthquakes.The research emphasizes the need to design structures capable of withstanding various loads, including dead, superimposed dead, live, wind, and earthquake loads, particularly in West Kalimantan, known for its historically low to moderate seismic activity. Recent earthquake records highlight the necessity of earthquake-resistant design for safety and durability. Structural analysis confirms the building's stability against seismic forces, with a modal participation ratio meeting SNI 1726:2019 requirements, indicating robust response under seismic loads.The study also assesses inter-story drift and P-Delta effects to ensure they meet allowable limits, which is crucial for preserving structural integrity and preventing post-earthquake instability. A detailed reinforcement design following SNI 2847:2019 enhances structural strength and durability, especially when under seismic loading. The foundation design uses tailored hollow spun piles to provide sufficient bearing capacity and stability. This approach demonstrates resilience against potential seismic events in low-to-moderate seismic regions, highlighting the importance of integrating seismic design principles and ductility considerations for effective earthquake hazard mitigation.
Extremely Rapid Progression of Oral Cavity Carcinosarcoma
Authors:   National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco., Kenza Berrada , Yahya El Harass ,   National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco., Sanaa Amalik ,   National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco., Rachida Latib ,   National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco., Youssef Omor ,   National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Published: April 2024

Carcinosarcoma is a very rare malignant tumor of the salivary glands including accessory salivary gland, associating malignant mesenchymal and epithelial tissue. It usually occurs after 50 years of age. Its prognosis is very poor. We present a case of carcinosarcoma having evolved extremely rapidly.
Intra-Peritoneal Rupture of a Benign Ovarian Teratoma - A Rare Complication of This Relatively Common Entity
Authors:   Assistant Professor, Dept. of Radiodiagnosis and Imaging, Government Medical College and New Civil Hospital, Surat, R Arora , P Desai ,   Professor and Head, Dept. of Radiodiagnosis and Imaging, Government Medical College and New Civil Hospital, Surat, P Jikadara ,   Senior Resident, Dept. of Radiodiagnosis and Imaging, Government Medical College and New Civil Hospital, Surat, S Deshpande ,   Senior Resident, Dept. of Radiodiagnosis and Imaging, Government Medical College and New Civil Hospital, Surat
Published: April 2024

Mature cystic teratoma is a cystic tumor composed of welldifferentiated derivations from at least two of the three germ cell layers (ectoderm, mesoderm, and endoderm). These tumors are usually complicated by torsion, with rupture and malignant transformation to be relatively rare. Here we present a case of a 25-year-old woman with complaints of sudden onset generalized acute abdominal pain. Her ultrasound pelvis revealed a large anechoic lesion with internal chunky calcification as well as hyperechoic internal contents (like that of fat) in the pelvis and left adnexa, extending up to the midline. Mild to moderate loculated ascites, peri-hepatic and intraperitoneal nodularity were also seen, representing changes of peritonitis. On CECT abdomen and pelvis, focal discontinuity was seen within the pelvic cyst wall with evidence globular free fat contents within the peritoneal cavity. Findings related to peritonitis were corroborated on CT. The imaging findings were suggestive of underlying peritonitis, secondary to the intra-peritoneal rupture of dermoid and release of its internal fat and fluid contents.
Help, My Lung is Trapped! – A Case Report
Authors:   Radiologist, Shahid Gangalal National Heart Centre, Bansbari, Kathmandu, Nepal, A Naura , NP Neupane ,   Radiologist, Shahid Gangalal National Heart Centre, Bansbari, Kathmandu, Nepal, A Regmi ,   Radiologist, Shahid Gangalal National Heart Centre, Bansbari, Kathmandu, Nepal, K Rajlawot ,   Radiologist, Shahid Gangalal National Heart Centre, Bansbari, Kathmandu, Nepal
Published: April 2024

Trapped lung is defined as the inability of the lung to expand fully and fill up the thoracic cavity because of a restricting fibrous visceral pleural layer preventing apposition of visceral and parietal pleura. It is a sequela of a previous inflammation of the pleural space and has variety of causes. Chest radiograph and thoracic ultrasound is the key imaging modalities for the diagnosis usually with a history of preceding pleural drainage. Typical imaging features include visceral pleural peel, basal pneumothoraces, ipsilateral volume loss and lobar atelectasis. Management aims at relief of symptoms and enabling full lung re-expansion. It is usually associated with high morbidity, therefore identifying patients with trapped lung is crucial for early treatment and positive patient outcomes. We present a case of trapped lung of a patient with previous history of pulmonary tuberculosis and chronic right pneumothorax.
A Case Report of Progressive Multifocal Leukoencephalopathy in Pediatrics: When and How to Think About it?
Authors:   Pediatric and Gynecology Radiology Department, Children’s Hospital, University MOHAMMED V, Rabat Morroco, Harras Yahya El , Sfar Kaouthar ,   Pediatric and Gynecology Radiology Department, Children’s Hospital, University MOHAMMED V, Rabat Morroco, Chehrastane Rachida ,   Pediatric and Gynecology Radiology Department, Children’s Hospital, University MOHAMMED V, Rabat Morroco, Allali Nazik ,   Pediatric and Gynecology Radiology Department, Children’s Hospital, University MOHAMMED V, Rabat Morroco, Chat Latifa ,   Pediatric and Gynecology Radiology Department, Children’s Hospital, University MOHAMMED V, Rabat Morroco, Haddad Siham El ,   Pediatric and Gynecology Radiology Department, Children’s Hospital, University MOHAMMED V, Rabat Morroco
Published: April 2024

Progressive Multifocal Leukoencephalopathy (PML) is a life-threatening demyelinating brain disease, usually caused by reactivation of a rare opportunistic infection with JC virus. This pathology is strongly associated with immunosuppressed states, with primary PML developing in an immunocompetent patient is very rare. Imaging has an important role in orientating the diagnosis. We report the case of an 8 years old girl, who was on chemotherapy, and suffered neurologically. Her MRI showed PML lesions. Through this case, we provide a review of the literature about this rare pathology to help clinicians and radiologists evoke it.
Systematic Review of Deep Learning Approaches for Automatic Segmentation of Abdominal Aortic Aneurysm and Thrombus on Computed Tomography Angiography Images
Authors:   Lincoln Medical Center, USA, Khrisat Tarek , Ashe Jamie ,   Lincoln Medical Center, USA, Guo Xutong ,   St’ George’s School of Medicine, USA
Published: April 2024

Abdominal Aortic Aneurysm (AAA) is a potentially life-threatening condition characterized by the enlargement of the abdominal aorta. Computed Tomography Angiography (CTA) is a widely used diagnostic tool for AAA, and accurate segmentation of the aneurysm and thrombus is critical for treatment planning. Deep learning approaches have shown promise in automating the segmentation process. We conducted a systematic review of the literature to evaluate the performance of deep learning methods for automatic segmentation of AAA and thrombus on CTA images. Six studies were identified that met our inclusion criteria. The studies utilized various deep learning architectures and loss functions to segment AAA and thrombus, and reported performance using metrics such as sensitivity, specificity, accuracy, and Dice coefficient. The results indicate that deep learning methods can achieve high accuracy and Dice coefficient values for segmentation of AAA and thrombus on CTA images. However, the performance of the methods varied depending on the specific architecture and loss function used. Further research is needed to determine the most effective deep learning approach for automatic segmentation of AAA and thrombus on CTA images.
Cortical Laminar Necrosis: Imaging Features and Etiological Oorientation
Authors:   Pediatric Teaching Hospital, Department of Radiology, Mohammed V University, Rabat, Morocco, Bahlouli Nourrelhouda , Chait Fatima ,   Pediatric Teaching Hospital, Department of Radiology, Mohammed V University, Rabat, Morocco, Allali Nazik ,   Pediatric Teaching Hospital, Department of Radiology, Mohammed V University, Rabat, Morocco, Haddad Siham El ,   Pediatric Teaching Hospital, Department of Radiology, Mohammed V University, Rabat, Morocco, Chat Latifa ,   Pediatric Teaching Hospital, Department of Radiology, Mohammed V University, Rabat, Morocco
Published: April 2024

Cortical laminar necrosis corresponds to neuronal ischemic remodeling with gliosis and accumulation of lipid-rich macrophages secondary to various etiologies: hypoxia, prolonged arterial hypotension, hypoglycemia, status epilepticus or arrest. Diffusion and T2 (FLAIR) show cortical and basal ganglia hypersignal from the first 24 hours. T1 shows cerebral edema during the first two weeks and a characteristic spontaneous cortical and basal ganglia hypersignal delayed and transient (3rd week). On T2*, the cortical lesions do not show any asignal, which makes it possible to differentiate them from a hemorrhagic transformation. Cortical contrast can be observed from the first weeks and for several months (up to 9 months in case of focal ischemia) and translates a rupture of the blood-brain barrier. In CT, hypodense and hyperdense gyriform density abnormalities are seen depending on the time.
Mindfulness Training Improves Sport Performance via Inhibiting Uncertainty Induced Emotional Arousal and Anger
Authors:   Department of Neurology, the Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, 210023, China, S Gu , Y Li ,   Department of Neurology, the Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, 210023, China, Y Jiang ,   Department of Neurology, the Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, 210023, China, JH Huang ,   Department of Neurology, the Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, 210023, China, F Wang ,   Department of Neurology, the Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, 210023, China
Published: April 2024

Mindfulness training has gained popularity in the scientific field, and has been proposed as an efficient psychotherapy for affective disorders. Mindfulness training requires the individual to pay attention to the good things that are happening “right now and here” and neglect the nervous uncertainty. Uncertainty (un-expectancy) plays a critical role in inducing stressful emotions during sport games, and mindfulness training is especially useful in calming the body peacefully for the athletes. In this paper, we will review experimental studies and propose theoretic speculations concerning uncertainty and emotional arousal during sport games. We first analyzed the effects of emotions on sports according to two dimensions (arousal and valence), next we analyzed the effects according to our previous three-primary-color emotional theory, which suggested that there are three prototypical emotions (Joy, Fear and Disgust). In addition, we proposed that anger might be the only basic emotion that can only be evoked by others’ behavior responses and directly affect sport performance. Furthermore, we propose that emotional arousal activates the sympathetic and norepinephrine system, while mindfulness activates the para-sympathetic and dopamine system. Therefore, mindfulness will activate the neural systems that are totally different or contrary the emotional arousal systems to induce peaceful mind. This review will contribute greatly to theoretical and empirical explorations of emotional regulations with mindfulness during sports.
The Effect of 6-Meter Underwater Diving Intervention on Recovery of Exercise-Induced Fatigue
Authors:   Faculty of Medicine, Macau University of Science and Technology, Macau, China, Q Ma , D Wu ,   School of Physical Education, Guangdong Business and Technology University, Zhaoqing, China, Y Yue ,   School of Physical Education, Guangdong Business and Technology University, Zhaoqing, China, T Zhong ,   Faculty of Medicine, Macau University of Science and Technology, Macau, China, X Yu ,   Faculty of Medicine, Macau University of Science and Technology, Macau, China, Y Xiao ,   Faculty of Medicine, Macau University of Science and Technology, Macau, China, L Wang ,   Faculty of Medicine, Macau University of Science and Technology, Macau, China
Published: April 2024

Objective: To evaluate the effect of 6-meter underwater diving on recovery of exercise-induced fatigue and explore the potential mechanism. Method: Thirty-three male sophomores majored in physical education were included in this self-control, cross-over study. The fatigue was induced through programed swimming exercise at same intensity for both control and intervention groups. After exercise-induced fatigue, the subjects recovered through sitting on the floor and 6-meter underwater diving for 15 minutes in control and intervention groups respectively. The parameters observed included Heart Rate (HR), Critical Flicker Frequency (CFF), Simple Reaction Time (SRT) and Standing Long Jump (SLJ). Results: The HR was faster after exercise and recovery compared to that before exercise in both groups. SLJ was shorter after recovery compared to before exercise fatigue in both groups. After diving recovery, the CFF was lower than that before exercise fatigue, while the index of SRT was higher than that before exercise fatigue. Compared with the control group, the HR and SRT were significantly lower, but the SLJ and CFF were significantly higher in the intervention group than those of control group (HR, p<0.05; SRT, p<0.01, SLJ, CFF p<0.01). Conclusion: The fatigue recovery effect of 6m underwater environment is better than that of land recovery. The low temperature, mild hyperbaric oxygen, water pressure and buoyancy in under water environment may promote the repair of muscle and motor nerve after exercise and improve the exercise performance after intervention.
Ternary Complex-Templated Dynamic Combinatorial Chemistry for the Selection and Identification of Homo-PROTACs
Authors: Diehl Claudia , Salerno Alessandra , Ciulli Alessio
Published: April 2024

Dynamic combinatorial chemistry (DCC) leverages a reversible reaction to generate compound libraries from constituting building blocks under thermodynamic control. The position of this equilibrium can be biased by addition of a target macromolecule towards enrichment of bound ligands. While DCC has been applied to select ligands for a single target protein, its application to identifying chimeric molecules inducing proximity between two proteins is unprecedented. In this proof-of-concept study, we develop a DCC approach to select bifunctional proteolysis targeting chimeras (PROTACs) based on their ability to stabilize the ternary complex. We focus on VHL-targeting Homo-PROTACs as model system, and show that the formation of a VHL2:Homo-PROTAC ternary complex reversibly assembled using thiol-disulfide exchange chemistry leads to amplification of potent VHL Homo-PROTACs with degradation activities which correlated well with their biophysical ability to dimerize VHL. Ternary complex templated dynamic combinatorial libraries allowed identification of novel Homo-PROTAC degraders. We anticipate future applications of ternary-complex directed DCC to early PROTAC screenings and expansion to other proximity-inducing modalities beyond PROTACs.
REINDEER: A Protein-Ligand Feature Generator Software for Machine Learning Algorithms
Authors: Rayka Milad
Published: April 2024

Machine learning-based scoring functions, which apply feature-generation methods for protein-ligand representation, have become ubiquitous in the past few years for binding affinity prediction. However, most of these feature-generation techniques are hidden inside papers and their corresponding codes. In this manuscript, we introduced REINDEER software to make these methods accessible to other users. REINDEER has been developed based on minimum dependencies and parallelization aims by Python programming language. The current version of REINDEER (v0.1.0) only includes feature generation methods from RF-Score, ET-Score, ECIF∷LD-GBT, and OnionNet-2 scoring functions. REINDEER provides a command line interface, graphical user interface, and usage within Python code capabilities to access these methods. Also, a case study on PDBbind refined set v2020 is presented to evaluate REINDEER abilities. REINDEER software is available at https://github.com/miladrayka/reindeer_software.
Assessing the Design Rules of Electrides
Authors: Yao Zhikun , Zhao Yanzhen , Zhang Wenjun , Burton Lee
Published: April 2024

There are three heuristic criteria commonly used to identify electrides: an apparent valence of plus one, empty space in the crystal structure and the presence of a strongly electron-donating cation. We evoke and explore these criteria by mapping probable charges to a database of all known materials and isolating around around 4,000 compounds that are likely to exhibit an oxidation state of +1. Of these, we identify peaks in off-atom electron density by density functional theory and discuss the validity with which the design rules can be applied to these likely electrides. In doing so, we recover 4 experimentally confirmed electrides among 51 candidates identified as potential new electrides that were not considered previously. All results for each candidate are provided but perhaps of especial significance is the material Ba3AlO4 that has similar composition, components and chemistry to the stable and popular electride catalyst Ca12Al14O32. Overall, we find that the valence and void space rules are surprisingly useful but that there is a breadth of chemistry to electrides that can be severely restricted by considering only alkili and alkali earth metal compounds.
Solid-Phase Synthesis of Diverse Macrocycles By Regiospecific 2-Pyridone Formation: Scope and Applications
Authors: Abboud Skander , Kodadek Thomas
Published: April 2024

This study introduces a novel solid-phase macrocyclization method generating 2-pyridone rings. This method relies on the intramolecular condensation between secondary and tertiary dimethoxy-propionic amide (DMPA) units. This selective reaction leads to the formation of a single, well-defined regioisomer. The method demonstrates remarkable efficiency in producing diverse peptidic and non-peptidic bioactive targets, paving the way for the development of innovative macrocycle libraries featuring the 2-pyridone unit.
Spatio-Temporal Analysis of Natural Focal Diseases on the Territory(Anthrax) of the North Kazakhstan Region
Authors:   M. Kozybayev North Kazakhstan University, Mazhitova G. Z. , Pashkov S. V. ,   M. Kozybayev North Kazakhstan University
Published: April 2024

The article presents the results of study of actual focal disease for the North Kazakhstan region – anthrax. The historically established livestock specialization and excessive concentration of livestock in a limited area (albeit short-term), the presence of favorable natural and landscape conditions for the preservation of the causative agent of anthrax infection (primarily the soil and climatic factor) led to the formation of numerous foci of this disease within the region. The questions of spatio-temporal manifestation and spread of anthrax infection on the territory of the region are considered. The retrospective analysis of the epizootic and epidemic processes of anthrax for 1938– 2022 was performed using archival, stock, and statistical materials. The study was carried out using GIS technologies, then a database, a series of electronic maps and a regional thematic geoinformation system “Anthrax in the North Kazakhstan region” were created. It has been determined that the greatest potential danger (epizootic and epidemic intensity) of anthrax manifestations is typical for the northern and central parts of the region. Within the boundaries of natural landscape units, the maximum risk of anthrax infection was recorded in the forest and steppe area and the valley of the river Ishim. Practical recommendations are proposed for improving measures aimed at preventing anthrax: annual full vaccination of farm animals, sanitary and epidemiological control over slaughtering points and the state of anthrax burials, establishing and maintaining a buffer zone when grazing livestock near stationary-unfavorable foci.
Assessment of technogenic acoustic background influence on y-spectrometer readings at registration of y-radiation spectra
Authors: Elokhin A. P. , Ulin S. E. , Majidov A. I. , Shustov A. E.
Published: April 2024

The paper presents theoretical and experimental data determining the effect of acoustic perturbation on the readings of a γ-detector (CGS) with a working medium (high-pressure xenon gas) operating in the field of ionizing radiation. For this purpose, a chain of events is considered: an acoustic wave falls on the surface of the CGS, passes through and produces a perturbation in the gas which forms a non-uniformity of pressure distribution in the working medium. Exposure to ionising radiation leads to the formation of positive ions in the gas, the mobility of which is much lower than the mobility of free electrons, which are the main carriers in CGS. The experiments are carried out using an unmanned dosimetric complex BDK with a carrier in the form of (helicopter-type UAV) on which dosimetric equipment used for radiation control of the environment in conditions of its radioactive contamination is attached. Theoretical results obtained by solving the wave equation of sound wave passage in xenon filling the CGS are presented in the form of xenon density. The obtained data allowes us to obtain the radial distribution of the current density at different moments of the harmonic acoustic oscillation period. Experimental data demonstrated frequency characteristics of acoustic load and their amplitude values in different modes of UAV operation. The results of the research determine the recommendations that should be taken into account when using UAVs as carriers of dosimetric equipment in radiation monitoring of the environment.
Development of methods and means to improve environmental, radiation and industrial safety of NPPs with WWER-1200
Authors: Proskuryakov K. N. , Khvostova M. S.
Published: April 2024

The introduction provides an overview of scientific research on the sources of generation, characteristics and classification of infrasound. It is noted that infrasound has a number of features related to the low oscillation frequency of the elastic medium and the diffraction property. Infrasound has harmful effects on hearing, breathing, vision, gastrointestinal tract, nervous and cardiovascular systems, brain and vestibular apparatus, leading to decreased performance, general malaise and premature aging of the human body. The methodology of theoretical substantiation of methods for detecting previously unknown sources of infrasound, improving the environmental, radiation and industrial safety of nuclear power plants with WWER-1200 is based on the use of digital acoustic models of primary circuit equipment responsible for operational safety developed under the guidance of K.N. Proskuryakov. The methodology of practical confirmation of the results of computational and theoretical forecasting of acoustic parameters of previously unknown infrasound sources is presented in the form of two stages: a) development of a methodology for verifying forecasting results and selection of power units No. 1, 2 of Novovoronezh NPP-2 in the form of objects; b) investigation of the conditions for the occurrence of vibro-infrasound resonances in the first circuit. The developed method for investigating infrasound sources has been verified at the WWER-1200 reactor plant. When discussing the results of the conducted research, previously unknown sources of infrasound were identified. Innovative methods of analysis and damping of infrasound sources have been developed and a patent for invention No. 2803181 «A method for preventing resonant interaction of vibrations of water-water power reactor equipment with acoustically standing waves and a device for its implementation» has been obtained. The errors of the chief designer of reactor installations with WWER in the regulations for the launch of new power units are noted; their negative consequences for the health of personnel and the condition of equipment responsible for environmental, radiation and industrial safety of nuclear power plants with WWER are indicated
Modern approaches to determining the standardised parameters of vibration state of NPP steam pipelines
Authors: Kravets S. B. , Kuzin S. A. , Smolin A. Yu.
Published: April 2024

During the operation of NPP steam pipelines the main damaging factors are not only corrosion and erosion leading to thinning of the pipe wall but also fatigue damage resulting not only from temperature self-compensation efforts, but also high vibration load. As practice shows, the most promising direction of ensuring the vibration resistance of steam pipelines at present is the computational and experimental study of the stress-strain state of pipelines under vibration loading. This work shows that the strength of the most commonly used standard sizes of steel pipelines under the influence of vibration loads is determined in accordance with Russian State Standard R 59115.9-2021. Taking into account the stress concentration, the amplitudes of the conditional elastic reduced stresses were determined for the 4 variants of the calculation schemes accepted for consideration. The permissible amplitude of stresses from an operating condition of 60 years is determined. It is shown that the permissible voltage amplitude for the design temperature t = 350°C will be no more than 46.4 Mpa for a pipe made of 12X18H10T. As for NPP pipelines, the normalized vibration parameters in the regulatory documentation were not established until 2022, when the following vibration velocity limits were adopted for pipelines of nuclear power plants in Russian State Standard R 59115.11-2021, vibration resistance testing is not required: nmax up to 15 mm/s, nmsv up to 7 mm/s. Thus, currently in the Russian regulatory documentation there are no normalized values of vibration parameters (as a rule, vibration velocity) for pipelines selected depending on the frequency of vibration exposure. It is proposed to develop and introduce into the regulatory documentation frequency-dependent criteria for limiting vibration parameters of NPP pipelines, specified in accordance with the actual operating conditions of these pipelines.
Determining the minimum required cooling time of profiled assemblies at the Armenian Nuclear Power Plant taking into account the load schedule
Authors: Hakobyan M. A. , Ksenofontov A. I. , Sargsyan S. A. , Umarov S. B.
Published: April 2024

Determining the minimum required cooling time of profiled assemblies at the Armenian Nuclear Power Plant, taking into account the load schedule, is an analytical process to establish the shortest required period during which profiled assemblies used in the nuclear power plant energy process must remain in active use. This process considers factors related to changes in the electrical load on the station during different periods. Within the scope of this definition, an analysis of the technical characteristics of profiled assemblies is conducted as well as their impact on the overall performance of the nuclear power plant. Key considerations in the cooling time include operational safety, compliance with regulatory requirements, and efficient distribution of energy resources in accordance with the load schedule. The goal of this process is to ensure optimal and safe operation of profiled assemblies, adapted to changes in the electrical grid and aligned with the load schedule, thereby contributing to the more efficient functioning of the nuclear power plant. This study aims to substantiate the minimum required cooling time for profiled nuclear assemblies characterized by an average uranium enrichment of 3.82% and an average burnup of 45.7 Megawatt-days per kilogram of uranium (MWD/kgU). Calculations are performed using the ORIGEN-ARP program, part of the SCALE software package designed for the analysis and modeling of radioactive and nuclear processes. The study considers parameters such as the composition of nuclear assemblies, fuel burnup, modeling using the ORIGEN-ARP program, and safety analysis. The results obtained aim to make a significant contribution to enhancing the efficiency and safety of nuclear energy installations
Burnable absorber element (Gd and Er) use in the WWER-type reactor to increase the refueling time
Authors: Rahman A. S.K. , Uvakin M. A. , Hossen M. M.
Published: April 2024

In a WWER-type pressurized water reactor, high-neutron-absorbing materials can compensate for the excess reactivity. Theoretical and computational analyses were conducted in this article to use burnable absorbers placed in a fuel rod to reduce the reactivity margin for extending refueling time for WWER-type reactors. To investigate the reduction of the reactivity margin, the fuel burnup calculation was performed without a burnable absorber and with a combination of a variety of burnable absorbers, namely natural Gadolinium (Gd) and Erbium (Er), applying a simplified GETERA program. The calculation found that the variation of the quantity of the burnable absorber (Gd, Er) inside the fuel assemblies governs the reactivity margin for the fuel burnup and increases the efficiency of Uranium fuel (UO2). The combined use of Gd and Er leads to a smoother decrease in reactor reactivity due to a smaller Er absorption cross section, which makes it possible to reduce the total mass of Gd in the fuel element and reduce the blocking effect. In the calculation, Gd concentrations employed in the computation at 1.5% and 3%, while Er concentrations were used within the range of 0.1%–0.6%.
Shell tube exchanger parametric investigation and performance simulation using ansys
Authors: Malik F. Elmzughi , Mohammed A. Elhaj , Elhadi I. Dekam
Published: April 2024

Heat exchangers with shells and tubes are widely employed in the chemical, power generating, and petroleum refining industries. A three-dimensional simulation of a shell and tube heat exchanger with segmental baffles was performed in this paper. The research involves the use of commercial code such as ANSYS CFX, MATLAB, and Solid-Work, which incorporate modeling, meshing, and the use of finite element techniques to produce numerical results. The results have been achieved in transient situations. The purpose of this paper is to optimize and analyse temperature drops, pressure drops in side shells and tubes, stream-by-stream velocities, and parametric investigations such as the number of baffles, the distance between baffles, and the number of passes using the ANSYS program. The pressure drop that has been addressed shows that raising the baffle cut and reducing the baffle spacing have opposite impacts on the pressure drop. In many cases, the pressure drop on the shell and tube sidewalls was investigated as well. Pressure drop has been investigated in terms of the number of baffles, the gap between baffles, and the number of passes.
Recreational ketamine use can lead to irreversible bladder damage
Authors: Eaton Daniel , Kueppers Frank
Published: April 2024

An increasing number of young patients with severe bladder overactivity syndrome potentially caused by recreational ketamine use has been treated in our department. Ketamine has become a popular and increasingly used recreational drug in New Zealand. Ketamine bladder syndrome has been reported internationally; however, local New Zealand data do not exist. It can lead to irreversible damage to the bladder, and internationally, surgical procedures like cystectomy and urinary diversion or augmentation cystoplasty have been reported as necessary treatments.
Differences in life expectancy within and between countries: implications for domestic TAVI guidelines in Australia and Aotearoa New Zealand
Authors: Ryan Thomas , Ryan Jonathon
Published: April 2024

The advent of transcatheter aortic valve implantation (TAVI) has caused a paradigm shift in the management of aortic stenosis away from traditional surgical aortic valve replacement (SAVR). However, uncertainty remains about the long-term (>10 year) durability of TAVI valves, especially in younger patients. This viewpoint collates life expectancy data from Australia and Aotearoa New Zealand to propose sex-specific age-based recommendations for choice of SAVR versus TAVI in their respective general populations and among Aboriginal and Torres Strait Islander people in Australia and both Māori and Pacific peoples living in Aotearoa New Zealand.
The combined effects of ocean acidification, warming and light on Caulerpa spp.: The role of inorganic carbon physiology and species’ ranges
Authors:   , taise aleluia
Published: April 2024

Caulerpa is a widely distributed genus of chlorophytes (green macroalgae) that is important for its dietary, social, and coastal ecosystem value. Ocean acidification (OA) and ocean warming (OW) both threaten to change the distribution of macroalgae in New Zealand and globally. Two of the most common Caulerpa species in Te Whanganui a Tara Wellington, Aotearoa New Zealand, Caulerpa brownii and C. geminata, could have vastly different responses to both OA and OW because of their divergent dissolved inorganic carbon (DIC) uptake strategies and distance from range edge. However, responses to both stressors of OA and OW could be heavily mediated by light. To address these concerns, I conducted four manipulative laboratory experiments to test the effects of OA, OW and marine heatwaves (MHWs), and light and interactive effects of two or more stressors on Caulerpa species.

Responses in physiology and photo-physiology of both Caulerpa species to OA suggest that those macroalgae without a CO2 concentrating mechanism (CCM) and relying solely on diffusive CO2 for DIC will benefit more from OA due to the benefits of alleviation of current DIC limitation than those species which possess a CCM that are not currently DIC limited. Physiological and photo-physiological responses to OA were significantly impacted by irradiance, demonstrating the role of irradiance in mediating DIC physiology in Caulerpa species tested. I found that any benefits received from elevated CO2 under OA may be dependent on energy limitations which in turn affects photo-physiology differentially depending on the DIC uptake strategy operating. Growth and photosynthesis responses of Caulerpa spp., demonstrated that the species with a warm edge distribution in Wellington was more negatively impacted by OW than the species with a cold edge in Wellington, which was more tolerant to OW and MHWs. Exposure to multiple stressors (OA, OW, reduced irradiance) of a future ocean exhibited less severe responses to a combined stressors effect than the singular stressor effects. Overall, my research contributed new knowledge to add to literature about the effects of ocean change on macroalgae with various DIC uptake mechanism and distribution edge positions. The findings here provide evidence that for chlorophytes, especially Caulerpa spp., some species will likely survive under OA in future OW and reduced irradiance conditions in Wellington unless irradiance is further limited. These results suggest a shift in distribution range of Caulerpa spp. in New Zealand can be expected that could potentially change the community structure in these locations.
Comparative Efficacy of Whole-Brain Radiotherapy Combined with Supplemental Precision Radiotherapy and Whole-Brain Radiotherapy Alone for Brain Metastases
Authors: Dong Weiwei , Zhou Yun , Jiang Xiangyang , Zhou Yan
Published: April 2024

Objective: To investigate the efficacy of whole-brain radiotherapy combined with supplemental precision radiotherapy compared to whole-brain radiotherapy alone for brain metastasis. Methods: Twenty-six cases of patients with brain metastasis were observed from January 2020 to June 2023. Thirteen cases each were randomly assigned to the observation group and the control group. The patients in the observation group received whole-brain radiotherapy combined with supplemental precision radiotherapy, while those in the control group received only whole-brain radiotherapy. Results: Comparing the quality of life scores between the two groups, the data from the observation group was significantly superior (P < 0.05). The survival rate of the observation group was higher than that of the control group, and their survival time was longer (P < 0.05). Additionally, compared with the control group, the observation group exhibited lower levels of various serum tumor factors after treatment (P < 0.05). Conclusion: Whole-brain radiotherapy combined with supplemental precision radiotherapy demonstrates improved clinical efficacy, prolonged survival time, and enhanced quality of life for patients with brain metastasis. These findings warrant further study and promotion.
The styles of liturgical music of non-Pentatidists in the West and in Russia
Authors: Maksimov V. V.
Published: April 2024

The article is devoted to considering the history of two interconnected  phenomena: rock and roll, which originated and took shape in the United  States in the middle of the last century, and the so-called "second wave of  Pentecostalism" (Pentecostal awakening), the date of which also falls on this  decade. The clear influence of Pentecostal musical culture on the work of Elvis  Presley is shown. The further history of rock and roll and its connection with  religion is considered. The process of integrating foreign musical religious  culture into the practice of Russian neo-Pentecostal churches is analyzed, an  overview of the creativity and styles of Russian artists and musical groups is  given.
The aesthetic component of the revolution in the context of the aesthetics of history
Authors: Savelyeva A. B.
Published: April 2024

The author of the article raises the question of the aesthetic content  of the real historical process. The article examines history as a dramatic space  of human development, as a locus and topos of the manifestation of his creative  abilities, as a process that can be studied and described in the categories of classical aesthetics. According to the author, the objective course of history  itself has aesthetic characteristics, which makes it possible to use the concepts  and categories of aesthetics in the study of historical events. The source of the  aesthetic fullness of a historical event is the creative nature of human activity in  general, the revolutionary impulse, heroic enthusiasm and creative potential of  mass popular movements. The phenomenon of social revolution is presented as  an event in which the aesthetic component of historical action is concentrated.  The global revolutionary social shifts of our time are largely achieved through  the selfless steps and inspired social creativity of popular movements, whose  participants, whether they realize it or not, are engaged in practical, often heroic,  transformation of an imperfect world and the creation of a new, more perfect  one, the harmony of which is revealed as constructive solvability contradictions.