bluuebunny/crossref_metadata_2025 huggingface dataset:
Efektivitas Penegakan Hukum oleh Satlantas dalam Menanggulangi Pelanggaran Lalu Lintas Anak di Kota Malang
Authors: Zakaria Fahmi Arif , Wijaya Darajatun Indra Kusuma , Wijaya Christian Ade
Published: January 2025

Penelitian ini bertujuan untuk menganalisis efektivitas penegakan hukum oleh Satuan Lalu Lintas (Satlantas) dalam menangani pelanggaran lalu lintas yang dilakukan oleh anak-anak di Kota Malang. Metode yang digunakan adalah yuridis empiris, yang mengedepankan pengamatan langsung di lapangan. Hasil penelitian menunjukkan bahwa pelanggaran lalu lintas oleh anak-anak, seperti mengemudi tanpa Surat Izin Mengemudi (SIM) dan tidak menggunakan helm, merupakan fenomena umum yang berpotensi menimbulkan kecelakaan. Kendala yang dihadapi oleh pihak kepolisian meliputi kurangnya personel dan sarana prasarana. Penelitian ini menekankan pentingnya edukasi dan kerjasama antara kepolisian dan masyarakat sebagai langkah strategis untuk menciptakan keamanan berlalu lintas. Dengan demikian, upaya preventif dan represif yang dilakukan Satlantas diharapkan dapat mengurangi pelanggaran dan meningkatkan kesadaran hukum di kalangan anak-anak.
Peran Partai Politik Terhadap Kekuasaan Legislatif
Authors: Sandy Rifky , Algibran Ahmad , Habibie Bayu Rasya , Rahmawati Nurlaili
Published: January 2025

Penelitian ini mengeksplorasi peran vital partai politik dalam kekuasaan legislatif dengan pendekatan hukum normatif. Kekuasaan dalam suatu negara melibatkan kewenangan individu dalam tindakannya, yang dapat didistribusikan sesuai kebijakan negara. Partai politik menjadi perantara penting antara pemerintah dan pengelolaan sosial, menjalankan fungsi-fungsi kunci untuk memastikan demokrasi yang sehat. Komunikasi politik yang etis dan sopan berkembang seiring tumbangnya rezim Orde Baru di Indonesia, menonjolkan nilai-nilai demokrasi. Partai politik memainkan peran esensial dalam merekrut anggota yang dapat dipercaya oleh masyarakat sebagai calon legislatif. Dalam pemilu, mereka yang meraih suara terbanyak menegaskan manifestasi kedaulatan rakyat. Peran partai politik tidak hanya terbatas pada internalnya, melibatkan pembinaan dan pengaderan anggota, tetapi juga mencakup tanggung jawab konstitusional dan moral dalam membawa perubahan yang positif. Kesimpulannya, peran partai politik memiliki dampak signifikan terhadap perkembangan sistem politik, memainkan peran krusial dalam mencapai "mewujudkan kesejahteraan umum" sebagaimana tercantum dalam Pembukaan UUD 1945.
Penggunaan Drone dalam Konflik Palestina Israel dan Tinjauan Hukum Humaniter Internasional
Authors: Salsabilla Annisa , Khairani Nurul , Putri Syifa , Salsabila Fariezka , Hidayat Farsya , Lewoleba Kayus
Published: January 2025

Penelitian ini bertujuan untuk meninjau penggunaan drone oleh Israel dalam konflik dengan Palestina, dengan fokus pada pelanggaran Hukum Humaniter Internasional (HHI). Meskipun teknologi drone telah memperkuat pertahanan Israel, penggunaannya menimbulkan kontroversi terkait dampaknya terhadap warga sipil di Gaza. Berdasarkan Konvensi Den Haag 1907, pembatasan penggunaan senjata dalam konflik bersenjata menjadi penting, namun penerapannya terhadap teknologi drone masih kurang jelas dalam forum hukum internasional. Pelanggaran HHI yang teridentifikasi meliputi dampak terhadap warga sipil, termasuk korban tewas dan kerusakan infrastruktur yang meluas. Metode penelitian yang diterapkan dalam artikel ini adalah metode kualitatif yang menitikberatkan pada pendekatan yuridis normatif untuk menganalisis peristiwa konflik. Artikel ini menekankan perlunya regulasi yang jelas dalam HHI mengenai penggunaan drone untuk mencegah dampak yang merugikan pada populasi sipil dalam konflik bersenjata.
Tanggung Jawab Hukum Perusahaan Asuransi Jiwa Terhadap Kegagalan Pembayaran Klaim Asuransi Jiwa Bakrie
Authors: Dwi Syafi'i Azhari , Putra Widiyanto Alif , Farros Friyadhi Naufal , Kartika Dewi Ulva , Aora Fadilla Dea , Lubis Thondi , Aryanti Ramadhani Dwi
Published: January 2025

Dalam era kemajuan teknologi, kebutuhan manusia yang semakin kompleks mendorong pentingnya sebuah perlindungan melalui asuransi. Kasus perusahaan asuransi jiwa PT Bakrie Life,  menarik perhatian karena tantangan pembayaran klaim terkait produk inovatif mereka, Diamond Investa, saat krisis ekonomi global. Fokus penelitian adalah memahami perlindungan hukum bagi pemegang polis dan tanggung jawab perusahaan terkait kegagalan pembayaran klaim. Penelitian ini menggunakan pendekatan Kualitatif Studi Kasus dengan menganalisis secara mendalam terhadap isu-isu hukum yang terjadi pada kasus gagal bayar PT Bakrie Life serta melakukan studi literatur terhadap sumber - sumber bacaan yang terkait dengan permasalahan yang diteliti. Hasil dari penelitian ini diharapkan dapat memberikan wawasan kepada pembaca tentang pentingnya transparansi dan kewajiban perusahaan asuransi dalam melindungi pemegang polis dari risiko keuangan yang tidak terduga serta menekankan bahwa perlunya sebuah keseimbangan antara inovasi produk dan tanggung jawab hukum untuk memastikan keamanan finansial bagi para pemegang polis.
Analisis Hukum Terhadap Hak Hak Atas Tanah Ditinjau dari Undang Undang Pokok Agraria (Studi Kasus: Eksistensi Sultan Ground di Daerah Istimewa Yogyakarta)
Authors: Wijaya Arthur , Yudhanto Tajali , Rachma Najma , Betari Ilona , Bela Lovensky
Published: January 2025

Makalah ini bertujuan untuk membahas kompleksitas hubungan antara hak atas tanah berdasarkan ketentuan Undang-Undang Pokok Agraria (UUPA) serta menganalisis dampak dan relevansi Sultan Ground dalam kerangka hukum, dan mengidentifikasi status hukum tanah Kasultanan Kraton Yogyakarta. Penelitian ini merinci jenis dan hak-hak tanah yang diperoleh oleh negara berdasarkan UUPA. Fokus juga diberikan pada eksistensi Sultan Ground di DIY, yang terkait dengan tradisi dan budaya lokal, dan bagaimana regulasi nasional menghadapi eksistensi keistimewaan Sultan Ground ini. Hasil penelitian menunjukkan kompleksitas keberadaan Sultan Ground dalam konteks hukum nasional, dengan tantangan mengenai definisi status kepemilikan dan implementasi UUPA. Tanah Sultan Ground masih memerlukan klarifikasi status hukumnya dalam kerangka hukum nasional, sementara upaya antisipatif untuk mencegah penyalahgunaan hak terus menjadi perhatian pemerintah daerah.
Aktualisasi Nilai Pancasila dalam Implementasi Perwujudan Jaminan Sosial
Authors: Yusuf Ahmad , Najicha Fatma Ulfatun
Published: January 2025

Perkembangan pesat dalam bidang informasi dan teknologi telah membawa perubahan yang signifikan dalam kehidupan masyarakat. Teknologi tidak hanya mempengaruhi ekonomi, tetapi juga berdampak pada aspek politik dan sosial. Dalam konteks ini, Islam dan berbagai nilai sosial seperti kesejahteraan dan jaminan sosial memiliki peran penting dalam mengatasi tantangantantangan yang muncul. Artikel ini membahas pentingnya nilai-nilai Pancasila sebagai landasan ideologis Indonesia dalam membangun masyarakat yang adil, makmur, dan sejahtera. Pancasila juga merupakan sumber inspirasi untuk pembangunan sosial, ekonomi, dan politik yang bertujuan meningkatkan kesejahteraan masyarakat. Konsep Pancasila tidak hanya berasal dari negara, tetapi juga tercermin dalam kekayaan budaya dan spiritual masyarakat Indonesia. Penelitian ini menggunakan metode studi literatur untuk mengumpulkan informasi dari berbagai sumber terkait. Pembahasan mencakup definisi Pancasila, kondisi kesejahteraan masyarakat Indonesia, dan upaya untuk mewujudkan jaminan sosial. Kesejahteraan masyarakat diukur melalui berbagai indikator, termasuk aspek kesehatan, ekonomi, pendidikan, dan ketenagakerjaan. Penelitian ini menggarisbawahi pentingnya Pancasila sebagai fondasi dalam membangun masyarakat yang berlandaskan pada nilai-nilai keadilan sosial dan kesejahteraan. Aktualisasi nilai-nilai Pancasila dalam kehidupan sehari-hari masyarakat Indonesia dapat membantu mencapai tujuan jaminan sosial yang merata dan berkelanjutan.
TRANSIENT ELECTROMAGNETIC MONITORING OF THE CRYOLITHOZONE WITH INDUCTION COILS AND A CURRENT LINE: COMPARATIVE STUDY
Authors: Nechaev O.V. , Mikhaylov I.V. , Nikitenko M.N. , Glinskikh V.N.
Published: January 2025

The article considers the results of mathematical modeling of transient electromagnetic cross-borehole monitoring data for civil and industrial cryolithozone facilities containing thaw zones (taliks) in their vicinity. A solution to the direct problem is presented based on the Sumudu integral transform and the vector finite-element method for two types of borehole sources: induction coils and a less common electric current line, taking into account the frequency dispersion of the electrical conductivity of permafrost. Three-dimensional numerical modeling of the transient signals is performed in realistic geoelectric models of a gas-producing borehole and a residential building on piles. Based on the modeling results, we have revealed the main features and differences of transient cross-borehole monitoring with coils or a line as the source.
Human umbilical cord mesenchymal stem cell exosomes promote elastin production and acute skin wound healing via TGFβ1-Smad pathway
Authors: Zi Yi , Li Jie , Qian XinPing , Li Jian , Jin Yan , Zhang ZiBo , Jin YanHua
Published: January 2025

Background Skin wound healing is a complex physiological process influenced by multiple factors, including the patient's overall health status. Exosomes derived from human umbilical cord mesenchymal stem cells (hUCMSC-exos) have demonstrated considerable potential in enhancing wound repair. This study investigates the mechanisms through which hUCMSC-exos facilitate skin wound healing and evaluates their potential application in combination with hydrogels for clinical treatment. Method Human foreskin fibroblasts (HFF-1) were treated with varying concentrations of hUCMSC-exos to evaluate their impact on cell proliferation, assessed via the CCK-8 assay. Exosome uptake by HFF-1 cells was visualized using PKH26 dye staining, while flow cytometry was employed to analyze cell cycle changes. Cell migration was evaluated through scratch and Transwell assays. Gene expression levels of Collagen I, Elastin, and Fibronectin were quantified by qRT-PCR, while Elastin secretion was measured by ELISA. Western blotting was used to examine proteins in the TGFβ1-Smad signaling pathway. The role of SP1 in regulating Elastin gene expression was investigated by testing the SP1 inhibitor Plicamycin and examining hUCMSC-exos' ability to counteract its effect. Additionally, a chromatin immunoprecipitation (ChIP) assay was performed to analyze SP1 binding at the Elastin gene promoter. In vivo, the efficacy of hUCMSC-exos combined with hydrogels in promoting wound healing was assessed using a mouse skin wound model. Results hUCMSC-exos significantly enhanced HFF-1 cell proliferation at concentrations exceeding 1×10⁹ particles/mL and increased the proportion of cells in the S and G2/M phases. HFF-1 cells readily absorbed these exosomes, leading to improved cell migration. Treatment with hUCMSC-exos upregulated the gene expression of Collagen I, Fibronectin, and Elastin. The SP1 inhibitor Plicamycin reduced Elastin gene expression, an effect that was reversed by hUCMSC-exos. In vivo, the combination of hUCMSC-exos and hydrogels accelerated wound healing, enhanced collagen organization, and promoted the formation of elastic fibers and blood vessels. Conclusions hUCMSC-exos facilitate skin wound healing by promoting SP1 binding to the Elastin gene promoter, thereby upregulating Elastin expression and supporting extracellular matrix remodeling. These findings suggest a promising therapeutic role for hUCMSC-exos in clinical applications for wound healing.
tres concepciones de la vulnerabilidad
Authors: Agüero Claudio , Gallardo Allan
Published: January 2025

La primera parte de la investigación presenta un enfoque metateórico que reconstruye la discusión reciente sobre la noción de vulnerabilidad. Para ello propone ordenar el debate usando como criterio organizador el tipo de propiedad que es la vulnerabilidad. Así, distingue tres posiciones: intrínseca, extrínseca y disposicional. Estas tres posiciones son discursos evaluativos que pueden ser útiles para la formulación de políticas y para justificar normas. En la segunda parte, el texto analiza si esas posiciones pueden ser entendidas como concepciones en el sentido de Rawls y Dworkin. Se concluye que no son concepciones rawlsianas, pero sí pueden ser entendidas como concepciones dworkinianas. A partir de estas dos conclusiones el texto reflexiona sobre la necesidad de reconstruir el concepto de vulnerabilidad como una noción descriptiva, es decir, neutral a valores, sin valores y con independencia de valores.
Efficacy of Virechana Karma in the management of Uccha Rakta Chapa (Essential Hypertension) - A Clinical Study
Authors: R.K. Patel  , Abhilasha Patel
Published: January 2025

The management of various systemic disorders and found to effectively detoxify the body by elimination of vitiated Dosha. Various clinical studies have shown that therapeutic modalities of Shodhana followed by Shamana have better clinical response than just Shamana (Palliative treatment plan). It has also changed the approach of the researchers towards palliative role of various form of modalities in the diseases which are considered to be newly emerging and do not find place in the classical treaties. Essential Hypertension is a form of Hypertension that by definition has no identifiable causes and is the most common type of Hypertension affecting 90% of Hypertensive patients and accounts to approx. 6% of deaths world-wide. The involvement of Pitta and Kapha is undisputed in the pathogenesis of Hypertension along with Vikriti of Vyan Vayu because it is Vyanavayu that facilitates Rasa, Rakta Samvahana. Keeping above view into consideration, it was thought desirable to consider Virechana as an appropriate. Virechana is considered to remove the Margavarodha, eliminates the morbid Doshas and regulate movement of Vata by its Anulomana action. Thus, it corrects the Rasa-Rakta Samvahan and helps to regulate the activity of heart and helps to reduce blood pressure.
An overview of Vyadhikshmatva (Immunity) in the promotion of health
Authors: Ishwari Sachan  , Chetna Rathor  , Hemant Kumar
Published: January 2025

Health is a basic element of achieving all the desires of life. A long healthy life has been the wish of every being since antiquity. Ayurveda is the science of life with the main aim of attaining health Ayurveda emphasizes a holistic approach, by implementing various practices such as Dincharya, Ritucharya, Sadvrutta and Achar Rasayan, daily intake of wholesome food, Rasayana therapies, etc. these fundamentals serve to regulate the immune system and promote overall health. Vyadhikshmatva (immunity) is described in Ayurveda as depending on Bala, Oja and Prakritik Shleshma, increasing Bala and Oja and adopting a way of living life we can help in enhancing immunity, so this attempt is aimed to review the concept of Vyadhikshmatva and its factors that help in health promotion.
Understanding the Relationship between Satva and Shareera w.s.r. to Personality Traits
Authors: Nikhil Dodamani  , Dhaneshwari H.A  , Punith P
Published: January 2025

Satva, Atma, Shareera are the three components. By the conjunction of these, existence of the living world is sustained. Understanding the relationship between these three components can help individual achieve a balanced and healthy life. Satva is one among the three innate qualities of the mind which governs psychosomatic manifestations and represents purity, virtue and enlightenment, while Rajas and Tamas denote passion /activity and inertia /ignorance respectively. Shareera on the other hand is a manifestation of Tridoshas (Vata, Pitta, Kapha). The relationship between Satva and Shareera is complex mechanism influencing each other in profound ways. Our thoughts and emotions generated by Satva can have direct impact and physical being. The body is influenced by the qualities of mind, and the mind is also shaped by the qualities of physical body. Personality traits are commonly defined as relatively stable pattern of thoughts, feelings and actions in which individual is different from the others. It is often seen as reflection of interplay between Satva and Shareera. Our innate characteristics are shaped by combination of genetic, environmental and personal experiences. These traits influence how we perceive ourselves and others as well as how we interact with world around us.
Panchmahabhoota Siddhanta and its Importance in Ayurveda
Authors: Archana Dhanpal Jugale
Published: January 2025

Panchmahabhoota Siddhanta is one of the important Siddhanta of Ayurveda. Panchmahabhoota are Akash, Vayu, Agni, Aap and Prithvi. Panchmahabhoota are structural unit of Body. Ahara Dravyas and Aoushadhi Dravyas are also made by Panchmahabhoota. As per Sankhya Darshana, Panchmahabhootas are originated from Tamasika and Rajasika Ahankara. Ayuraveda states that Panchmahabhootas are originated from five Sukshama Bhoota i.e., Shabda, Sparsha, Rupa, Rasa and Gandha. Theory of Panchmahabhoota is widely utilized in Ayurveda. On the basis of predominancy of Panchmahabhoota all the Dravyas are categorized as Parthiva, Jaleeya, Agneya, Vayaveeya and Akasheeya. As per Sushruta, Prakruti is five types based on Panchmahabhoota. Doshas are structural unit of Body which are also made up of Panchmahaboota. Shadrasa, Triguna i.e., Satwa, Raja and Tama are also made up of Panchmahaboota. In understanding Marma Vigyana knowledge of Panchmahaboota is important. Role of Panchmahabhoota is very important in Chikitsa.
A comparative clinical study to evaluate the efficacy of Hanu Basthi and Hanu Pichu with Ksheerabala Taila in Hanu Sandhigata Vata w.s.r. to TMJ Osteoarthritis
Authors: Varun TV  , Chaitra TM  , Vishnu Damodar  , Akshitha P
Published: January 2025

Osteoarthritis, is a degenerative condition of joint, in which the tissues in the joint break down over time and is more common in older people. People with osteoarthritis usually have joint pain and, after rest or inactivity, stiffness as main symptom. It is characterised by chronic degeneration of various hard and soft tissues around all joints. It can also affect the Tempero-mandibular joint and called as TMJ osteoarthritis. The non-dental causes of oral pain closely related to Tempero-mandibular disorder. So TMJ osteoarthritis can be correlated to the Hanu Sandhigata Vata due to the similarities in the symptoms of both. It is estimated that 22-29% of people in India have osteoarthritis. Radiological and autopsy surveys show a steady rise in degenerative changes in joints from the age of 30. By the age of 65, 80% of people have some radiographic evidence of osteoarthritis, although only 25% may have symptoms. In the case of TMJ osteoarthritis, it begins early and has been observed in over 20% of individuals over the age of 20 years and 40% of patients over 40 years of age. It affects both sexes with higher prevalence in women. As this is a new innovative topic and not much studies are conducted on the topic TMJ osteoarthritis, or Hanu Sandhigata Vata, so this study has been conducted.
An Insightful Analysis of Trichological Principles in Ayurveda: A Systematic Review
Authors: Dipti G. Godbole  , Sharanya CB  , Gururaj J
Published: January 2025

In Ayurveda, Kesha, meaning that which grows on the head, is a crucial indicator of overall health, encompassing aesthetic, functional, and health-related aspects. Ayurveda emphasizes the connection between hair, Prakriti (body constitution), Dinacharya (daily routines), and Sadvritta (ethical conduct), offering various treatments for Kesha Vikaras (hair disorders). These range from external applications (Bahya Lepa) to head oil therapies (Murdhni Taila). The study aims to compile references on Kesha Sharira, focusing on development, nourishment, Prakriti-based characteristics, and hair disorders, as well as to identify Arishta Lakshana (fatal signs) and Duta Lakshana (messenger signs) related to hair. The research draws information from classical texts like Charaka Samhita, Sushruta Samhita, Ashtanga Sangraha and Sharangadhara Samhita along with scientific databases such as Google Scholar, PubMed. The compilation highlights the structural aspects along with the physiological development and nourishment of hair. Prakriti-based characteristics influence hair types, with Vata, Pitta, and Kapha dominance determining hair texture and growth patterns. Significant data includes the identification of Arishta Lakshana seen on Kesha and how it determines the prognosis in a patient as well as a healthy person. The study also highlights the major disorders like Kesha Vriddhi (excessive hair growth) and Kesha Kshaya (hair loss), which result from Dosha imbalances or other underlying conditions. Treatments like Snehika Nasya and Pracchana provide effective management for these conditions. In conclusion, addressing Kesha Vikaras requires a holistic approach, integrating lifestyle changes, ethical practices, and treatment modalities to restore both physical and mental well-being, enhancing overall quality of life.
Clinical efficacy of Vrahat Dadimashtak Choorna in Sangrahani w.s.r. to IBS: A Critical Review
Authors: Mohit Arora  , Pavitra Malik
Published: January 2025

The purpose of this review article is to have a comparative review of Sangrahani with IBS (irritable bowel syndrome) with respect to modern medical science and to evaluate the efficacy of Vrahat Dadimashtak Choorna in treating Sangrahani w.s.r. to IBS.  At present time Sangrahani is correlated with IBS based on symptoms like alternate episodes of constipation and diarrhea (Mahurbadham mahurdravam), Stool accompanied by the passage of a large amount of mucus (Mala Niskasana with Shabda and Manda Vedena), fatigue (Durbalata Sadan Alasya). According to Ayurvedic literature, the potency and efficacy of Ayurvedic classical preparations depend upon the Rasa Panchaka, Desh (region), Kal (time), Ritu (season), their preparation method, and route of administration. This article mentions the efficacy of Vrahat Dadimashtak Choorna in treating Sangrahani w.s.r. to IBS. As per Acharya Sharangdhar, Vrahat Dadimashtak Choorna is also very useful for the treatment of other disorders like Atisaar (diarrhea), Gulma (abdominal tumor/abdominal lump), Mandagni (Improper digestion), Kasa (cough). All the contents of Vrahat Dadimashtak Choorna have been evaluated according to the research done by various research scholars. The efficacy has also been tested according to the Rasa, Guna, Virya, Vipaka described in Ayurvedic text.
A classical review on Avabahuka (Frozen Shoulder)
Authors: Sangita Verma  , Yogesh S. Kulkarni
Published: January 2025

Avabahuka is one among the Vataja Nanatmaja Vyadhis which affects the normal functioning of upper limbs there by affects the normal routine lifestyle of an individual. It is caused mainly by the Vyana Vata vitiation and gets Sthana Samshraya in the Amsa Pradesha. There it does the Shoshana of Shleshaka Kapha, Mamsa, Sira, Snayu leading to Bahupraspanditaharatwam, Shoola and Stambha. These clinical features closely resemble with painful stiffness and loss of motion of shoulder. After completion of treatment, significant improvement was observed in the parameters like Bahu Shoola, Stambha and Range of Movements. In Ayurveda Acharya’s have mentioned the specific line of treatment of Avabahuka are Agnikarma, Nasya, Swedana, Shamanoushadhis.
The Intersection of Ayurveda and Genomics: Exploring Ayurgenomics for Personalized Health Solutions
Authors: Yogesh Dilip Madgulwar  , Kalyani J. Shewalkar
Published: January 2025

In Ayurveda, Prakriti refers to an individual's inherent constitution or natural state, determined at conception by the unique balance of the three Doshas: Vata, Pitta, and Kapha. This constitution governs an individual's physical, mental, and emotional characteristics throughout life. Understanding one's Prakriti is key to personalized health approaches in Ayurveda, guiding diet, lifestyle, and treatment choices to maintain balance. The concept of genome can be loosely aligned with Prakriti in Ayurveda. Just as the genome contains the genetic code that dictates physical and biological traits, Prakriti determines one's physiological and psychological tendencies. Both systems emphasize the importance of individuality in health, with Ayurveda focusing on maintaining the balance of Doshas to prevent disease, much like genomics seeks to understand individual genetic variability for personalized medicine. Together, Prakriti and genome offer complementary insights into personalized health, rooted in ancient wisdom and modern science. Aim & Objective: To evaluate the Ayurvedic genetic concepts of Prakriti in relation to evidence based studies. Materials and Methods: Information extracted from various classics (Charak Samhita, Shusruta Samhita, Asthanga Sanghra, Asthanga Hridya) & Published information on recent articles in PubMed, Google scholar, Scope med & Dhara online data base were taken into consideration for review purpose. Reported data was analyzed & represented for current review. Conclusion: Ayurgenomics help to build personalised base treatment purpose for each entity of human beings in smart and efficient manner.
Rejuvenation of Ayurveda: Major Obstacles and A Way Forward
Authors: Tajinder Kaur  , Neena Rosey Kahlon
Published: January 2025

Ayurveda is again reviving and receiving a great deal of attention as a result of the role it plays in meeting the primary health care needs. The primary purpose of this study was to determine the role that Ayurveda plays in the delivery of health care to the rural masses as well as to investigate the issues that stand in its way. Exploratory research design was used to collect the information. The study found that Ayurveda is playing an important role in combating chronic diseases such as diabetes, arthritis, etc. Unsuccessful past experiences and affordability served as two major pull factors for respondents to turn to traditional medicine. Government dispensaries opened under AYUSH are encountering several challenges, such as inadequate infrastructure and a scarcity of doctors and medications. It is imperative for the government to prioritise and increase funding for traditional systems of medicine and organise training programmes for traditional practitioners with the aim of delivering healthcare services that are both secure and economically efficient.
Physicochemical Evaluation of Chakramuni (Sauropus Androgynus (L) Merr) with special reference to its Nutritive Values
Authors: Darshan N. Dhari  , Bhumishree G  , Satwik Poojar
Published: January 2025

Ayurveda the ancient traditional science which deals with maintenance of health of healthy individual and care of the diseased. There are many plants which are not mentioned in Ayurveda but are of great importance as a medicine as well as highly nutritious rich source of proteins and vitamins one such drug is Chakramuni (Sauropus androgunus). It is less known traditional herb drug not mentioned in classics but widely appreciated for its rich source of micronutrients and proteins. The presence of proteins, carbohydrates, calories, fat, fibers, minerals make it a Multivitamin Plant. In this article the determination of physico-chemical values with special reference to its nutritive values will be estimated.
Uses and Relevance of Artificial Intelligence (A.I) In Ayurveda
Authors: Kartik Sharma  , Aashish Patel  , Aswini Ramachandran
Published: January 2025

Introduction: Artificial intelligence (AI) plays a vital role in modern healthcare and is crucial to achieving global objectives such as the Sustainable Development Goals (SDGs) and the World Health Organization's (WHO) Triple Billion Targets. The growing adoption of AI in healthcare has revolutionized diagnostics, personalized treatments, and clinical decision-making. In traditional medicine systems like Ayurveda, AI offers significant opportunities, but its integration remains underexplored. Methods: A comprehensive literature review was conducted using research papers, books, peer-reviewed journals, and online sources. The study focuses on the integration of AI in Ayurveda, particularly in Prakriti (constitution) assessment, Dosha (bodily humor) evaluation, and Rasashastra (Ayurvedic alchemy). AI tools such as data mining, pattern recognition, and predictive analytics were analyzed for their potential to improve diagnostic procedures, therapeutic outcomes, and knowledge of Ayurvedic formulations. Results: AI shows promise in improving diagnostic precision and personalized care in Ayurveda through tools like Prakriti and Dosha evaluation. AI's data mining capabilities enable deeper insights into disease mechanisms, symptoms, and treatment protocols. Discussion: While AI enhances data management, analysis, and research efficiency in Ayurveda, its limitations must be recognized. Traditional Ayurvedic practices, especially in patient care and diagnosis, cannot be entirely substituted by AI technologies. AI should complement rather than replace the expertise of practitioners. Conclusion: AI holds significant potential to advance Ayurvedic knowledge, diagnosis, and treatment, particularly in Rasashastra. However, the role of expert Vaidyas remains irreplaceable, and AI should be viewed as a supportive tool in integrating traditional practices with modern healthcare.
An Insightful Review on Sandhana Kalpana
Authors: Gaurav  , Anoop Kumar  , Rachana Thakur
Published: January 2025

Ayurveda is an ancient medicine system. Over the course time, Ayurevdic treatments have evolved and changed. Rasashastra Evam Bhaishajya Kalpana is the branch of Ayurveda that deals with the preparation of medicines with herbs, minerals and metals. Sandhana Kalpana is one of the simplest but unique dosage forms which are widely used since ages. It is mainly used for health promotion and treatment of numerous diseases. Sandhana Kalpana includes every preparation that results out from the fermentation process. In Ayurveda, Dhataki Pushpa, Madhukpushpa, Surabeej and yeast are commonly used as Sandhana Dravya for fermentation process. Primarily, Sandhana Kalpana is divided into two types i.e., Madya Kalpana and Shukta Kalpana. Madya Kalpana are said to be alcoholic preparation where as Shukta Kalpana referred to acidic preparation. Sandhana Kalpana is used in wide range of diseases. Sandhana Kalpana are having nutritional value can be used even in children, lactating mothers and old age patients also. Asavarishta have a unique place among all the Sandhana Kalpana. They are mostly used among all Sandhana Kalpana due to their quick absorption, high efficacy, easy to prepare, easy to handle, easy to store and also easily palatable for patients. Sandhana preparations contain self-generated alcohol which acts as self preservatives having prolonged shelf life. The purpose of this article is to go through all the terminology of Sandhana Kalpana and to know more about therapeutic range of all these Kalpana so that they can be used therapeutically more in daily practice.
Study of Aama and Dysbiosis for Future Microbiological and Biotechnological Advancement in Ayurveda - Case Controlled Literary Study
Authors: Prakhar Goyal  , Kumar Gaurav  , Akshata N. Moger
Published: January 2025

Introduction: In Ayurveda there are various concepts that require special attention due to their complex nature and lack of understanding of human mind. One such concept is Aama that is so far considered as toxins or free radicles in body. Our limited understanding in advance sciences like biotechnology has limited us to understand these complex yet highly valuable concepts. Through this study we will try to understand Aama in the reference of gut biota dysbiosis and disease progression. Aim: To understand Aama in perspective of dysbiosis and establishing its direct relation with advance microbiological and biotechnological researches. Methodology: Study of major pathological conditions where Aama is involved, Study of affected biota and toxins (if involved/studied) in those conditions. And further evaluation using statistical test. Discussion: Such studies in the segment of Ayurveda can lead to understand the mechanism of various functional dynamics of body as described in Ayurveda. This can be helpful in developing the concepts further and enhance our understanding toward complexity of human body. Future of this study can be seen as complete understanding of this concept of Aama. Further using biotechnological tools we can develop investigations module for confirming presence or amount of Aama present in cell or body. Further studies in medicine can help us rule out the most appropriate medicines for various pathological groups of organisms.
A Multidimensional Integrated approach towards PCOS - Need of the Hour
Authors: Vidhya Sarode  , Aishwarya Bongane
Published: January 2025

Due to the rapidly changing lifestyles, habits and environmental conditions a veraciously growing picture of PCOS is emerging. The estimated prevalence in India is ranged from 3.7% to 22.5%.[1] PCOS is a common hormonal condition that affects women of reproductive age. It usually starts during adolescence but symptoms may fluctuate over time. It has varying symptoms ranging from irregular menses to chronic conditions like endometrial CA, heart diseases, etc. This article primarily deals with the various approaches which can be applied to treat PCOS depending upon patient’s condition and interest.
Management of Smack/Opium Addiction through Ayurveda Intervention : A Case Series
Authors: Mukesh Prajapati  , Madhavi Dholariya  , Ashwini Gaikwad  , Poonam Garg  , Anita Sharma  , Dinesh Kumar Kumawat
Published: January 2025

Opium and its derivative addiction are rampant in western Rajasthan, because it is easily available. Opioids, which include heroin (or its impure form, smack or brown sugar), a range of medicinal opioids, are used by about 2.1% of the population in India. Opium was first described by Acharya Bhavprakasha, Properties are Tikta and Kashay Rasa, Laghu, Ruksha, Sukshma, Vyavayi, Vikasi, Vedanasthapana, Nindrajanana, Shothahara and Aakshepahara. The opium-derived addictions withdrawal symptoms such as nausea, vomiting, diarrhoea, chills, body ache, sleeplessness and flu-like symptoms begin, these symptoms can grow severe enough to necessitate emergency medical attention, and in extreme situations, they might have life-threatening consequences for the users a result of respiration depression, and pupil dilation in the later stages. Diagnosis: The assessment was based on Clinical Opiate Withdrawal Scale (cows) before and after the treatment. Intervention: Effect have been applied to depict 5 cases of opium addiction in form of series who have been treated with Sameergaja Kerari Rasa in the tapering method (Padanshika Krama) starting with the dose of 375 mg along with Vishatinduka Vati dose of 125 mg twice a day along with Panchakarma procedures, Abhayanga, Swedana and Shirodhara for a period of 1 month. Result: Reduction in cows scale was observed, about 75-80% of symptoms subsided in all cases and the results have been reported very encouraging within a period of twenty to thirty days. Conclusion: Ayurveda treatment can be an effective and safe solution for opium/smack addictions.
A case study of Ayurvedic treatment of Grahani Roga
Authors: Rupanjali Das  , Pragayapriyadarshini Mallick  , Bharatilata Acharya
Published: January 2025

Grahani is an important part of the Mahasrotas (gastrointestinal tract). Grahani and Agni (digestive fire) have an Adhara Adheya Sambandha (mutual relationship). Jatharagni (digestive fire) governs the process of digestion, supported by the Tridoshas (three bio-humors). Due to a chronic imbalance of the Pachaka Pitta (digestive fire), Saman Vayu (the air entity that aids digestion), and Kledaka Kapha (the type of phlegm involved in digestion), a weak digestive fire (Mandagni) can lead to the release of food in its undigested form (Ama Utpatti), resulting in Grahani Roga. Any individual if suffering from symptoms like alternate passing of hard & loose bowel habits, abdominal pain, passing of foul smelling stool, mucus in faecal matter can be diagnosed as Grahani roga. In modern science, above symptoms can be correlated with IBS (Irritable Bowel Syndrome). In IBS the wall of the intestine becomes sensitive to even mild stimulus which causes excess abdominal cramps & hence the bowel movement alters along with indigestion. In India, IBS affects about 15% of adult population. This paper discusses the pathogenesis of Grahani Roga, a condition linked to impaired digestive function, and presents various treatment modalities, including herbs, Yoga, and lifestyle modifications.
Efficacy of Ayurvedic management of Timira w.s.r. to Simple Myopia - A Single Case Study
Authors: Sanfi A.P.M  , Pramila Mahala  , Shamsa Fiaz
Published: January 2025

Introduction: It is the most common refractive error of the eye common in children and young adults. Factors such as increased near-work activities (like computer use and reading), reduced time spend outdoors, and genetic predisposition are thought to contribute to the rising rates of Myopia. On the basis of symptoms Myopia can be correlated to Vatika Timira, for which treatment modalities have been mentioned and Ayurvedic treatments was done for the management of the case. Materials and Methods: A fully conscious male patient age of 26 yrs had visited Shalakya Tantra OPD, National Institute of Ayurveda, Jaipur, with chief complaints of defective distant vision in both eyes which was gradual painless and persistent since 3 years. He also complained of frequent dryness of bilateral eyes. The patient was treated with Internal medicines which are Chakshushya and Vathahara and Therapies like Parisheka, Nasya and Tarpana in sittings. Along with this Eye exercises are also advised. The treatments suggested for 3 months. Results: At the end of the study, there got significant improvement in visual acuity in both eyes and he got relief from dryness of bilateral eyes. Conclusion: Thus, it can be concluded that Ayurvedic approaches are helpful to control Simple Myopia.
Management of Complex Fistula in Ano, by IFTAK technique and Partial Fistulotomy - A Single Case Study
Authors: Prajapati Parth Rameshbhai  , Prashanth K
Published: January 2025

Since ancient time, fistula in ano has been the most prominent condition of all anorectal disorders. Despite two millennia of efforts, fistula in ano still remains a challenging surgical condition. Over the past few decades, various techniques have been evaluated in terms of preventing its recurrence and complications. The sign and symptoms of fistula in ano resembles with Bhagandara described in Ayurveda classics. Many treatment modalities are listed in Ayurveda classics for the management of this painful disease, Ksharasutra therapy is one among them that has been proved to be highly efficacious. Though Ksharsutra therapy is a popular treatment for fistula in ano, it does have few drawbacks. Long duration of treatment, post procedural pain and long scar are some to mention. As a result, in the present era IFTAK is emerging as an innovative technique for the management of fistula in ano, without compromising the outcome compared to traditional method of Ksharasutra treatment. In this case study, the IFTAK (Interception of Fistulous Tract and Application of Ksharasutra) and partial fistulotomy was used in complex low anal fistula in ano which shows great potential in reducing both the treatment duration and post-procedural pain.
An Ayurvedic management of Amlapitta: A Case Study
Authors: Athira Appu  , Sudeeksha Verma  , Manita Ahlawat  , Surendra Kumar Sharma
Published: January 2025

Introduction: Agni is the primary factor which decides whether the body is healthy or sick. According to Charaka pitta itself is Agni. Amlapitta a gastrointestinal tract disorder which developed due to the Vikriti of Pachaka Pitta. The Pachaka Pitta gets vitiated and it changes from normal bitter taste {alkaline} to Vidagda /sour (acidic) taste. The symptoms of Amlapitta can be seen in gastro esophageal reflux disease. Accompanying symptoms like nausea, vomiting, loss of appetite, acid belching and sour taste in mouth. Aim and Objectives: The primary aim of this paper is to study the efficacy of Shamana Chikitsa in Ayurveda in the management of Amlapitta. Materials and Methods: This is a case study of a 27-year-old female patient who had signs and symptoms of Amlapitta.  Ayurvedic Shamana Oushadas were used according to patients Prakriti, Avastha of Roga and Rogi, Ama, Agni for the follow-up and post-test assessments. Observation and Results: Improvement in the condition of patient in terms of Avipaka, Tikta Amla Udgara, Urokanda Daha Ruja, Utklesa, Dourbalya, Adhmana. This case study highlights the possibilities of Ayurveda and displays its evidence-based treatments.
A case study of Erandadi Guggulu and Sagni Upnaha Sweda in the management of Sandhigata Vata (Osteoarthritis)
Authors: Pendro Singh Shyam  , Ojha Aruna  , Pawale Singh Tribhuwan  , Upadhyay Byomesh
Published: January 2025

The reported case was a 58-year-old male with late-stage osteoarthritis (OA) (Sandhi Gata Vata) of both knee joints accompanied by pain & mild swelling reducing the movement of both knee joints. The radiology (X-ray) report confirmed it reduces the space between both knee joints. Initially, the knee scores of pain, movement, and stability were poor, and the function score was reduced. Erandadi Guggulu was given continuously for 90 days & External Sagni Upnaha Sweda treatment was given in two regimens for 90 days. A visual analog scale for pain, knee swelling measurement by measuring tape, and knee joint movement score by goniometer and Ayurveda clinical assessment criteria were used to evaluate the effects of treatments on 15 days. After treatment for 90 days, the Knee scores of pain and movement were also improved to a good level and the function score was improved to an excellent level also reducing the swelling of both joints. During the follow-up period, joint symptoms and signs and the knee scores were mildly changed. In conclusion, this OA patient’s quality of life was improved by the treatment of Erandadi Guggulu described in Bangasen Samhita Vatarogadhikara and Sagni Upnaha Sweda which is described in Chikitsa Adarsh.
Study the Vrushya effect of Bastand Ksheer Basti in Ksheena Shukra with special reference to Male Infertility
Authors: Tirth Mihir Shah  , Kalpana Dhomse
Published: January 2025

Male infertility which has substantial 76.7% increase in the last decade in India. The affected area of this problem has no bar irrespective of metro cities as well as small town population. Due to dietary and lifestyle changes in modern era, cases of male infertility are rising. Ayurved mentions various causes of Shukradushti which leads to Vandhyatva. This study was an approach for practical application of Samanya-Vishesh Siddhant in male infertility. Testicles of goat were used for preparation of Siddha Ksheer for Yapan Basti. Basti Karma plays a major role in Ksheen Shukrajanya Avastha. This study mainly focuses on Shukrajanan effect; hence all the patients were previously treated by Shodhan Chikitsa for Shukrashuddhi before the administration of Bastand Ksheer Basti. This study was performed on 5 patients with age ranging in between 20-40 years. Sperm count below 15 million/ml with primary infertility with Pratyatmaka Lakshana of Kshinashukra. Patients were given above Basti regimen for 8 days. Bastand Ksheer Basti was prepared and administered. Findings: All Five patients have shown significant effect on objective pathological parameters of semen analysis. Two patients got successfully treated for infertility and are presently under Gynecological observation for their partner’s ANC. There is a wide scope of using this simple Samanya-Vishesh Siddhant and Shukradushti Chikitsa in male infertility.
An Invitro study to evaluate the Krimighna Karma (Antimicrobial Activity) of Dugdhika Patra (Euphorbia hirta Linn.) against Staphyloccus aureus
Authors: Prajwal C R  , Nisarga K S  , Pradeep  , Anuradha K N
Published: January 2025

Background: Today’s world’s mortality rate depends on the infectious diseases and accounts for about 50% of all deaths. Deadly diseases of this century were mainly caused by bacterial infections. Biologically important plants were discovered by evaluation of ethnopharmacological data and they are locally populated with immediate therapeutic action. The recognition of any of the Dravya is through its Karma (Action). The Karma is mainly explained with the help of Rasa Panchaka in science of Ayurveda. Krimighna Karma is one such Karma which is responsible for the destruction of the Krimi. The plant Dugdhika is widely used in traditional medicine to cure various diseases, especially gastrointestinal disorders, respiratory disorders and skin disorders. Aim: To evaluate the Krimighna Karma of Dugdhika Patra Swarasa against Staphylococcus aureus bacteria. Materials and Methods: In this study, Dugdhika Patra (Euphorbia hirta Linn.) Swarasa was evaluated for its antibacterial activity against Staphylococcus aureus bacteria using well diffusion method. Observations and Results: The zone of inhibition was observed through agar well diffusion method. Swarasa had shown maximum Zone of inhibition (9mm) for Staphylococcus aureus bacteria when dispensed directly and moderate zone of inhibition (6mm) with diluted concentration after 24 hours of incubation period when compared to control group but not as that of standard group. These findings established the potential of Dugdhika Patra Swarasa has effective antibacterial agent against Staphylococcus aureus. However, further studies are needed to evaluate the active compounds and probable medicinal benefits in humans by clinical trials.
Integrative Approach to Weight Loss: The Impact of Yogasana Practice and Diet in Obesity
Authors: Rohit Pawar  , Nileema Shisode
Published: January 2025

This case report explores the weight loss journey of a 26-year-old female achieved through an integrative approach combining Yoga, intermittent fasting, and diet correction. Starting with a BMI of 28.4 kg/m² and weight of 71 kg, the patient underwent a 10-month program designed to improve physical fitness and metabolic health. The intervention resulted in measurable improvements, including an 18.17% reduction in weight, a 17.96% decrease in BMI, and a 15.38% improvement in HbA1c levels. The study demonstrates the effectiveness of a multidisciplinary approach in managing obesity and associated metabolic conditions.
Preventive strategies in Ayurveda: A focus on Satvavajaya (promotion of mental health)
Authors: Shantibhushan R. Handur
Published: January 2025

Ayurveda being an ancient system of medicine provides a holistic approach to the health in the form of prevention and treatment of illness. Ayurveda gave importance for both physical and mental health. Among preventive strategies of mental health, the concept of Satvavajaya plays a crucial role. This article explores the concept of Satvavajaya principle, its practical application and relevance in contemporary mental health care.
Critical Review on Niruha Basti w.s.r. to Charaka Samhita
Authors: Preeti Banthanal  , Madhusudan Kulkarni
Published: January 2025

Ayurveda is an ancient Science of medicine. It originates from Atharveda and since Vedic period to till date it's Principles, medicines and treatment modalities like Panchakarma were proved very useful for treatment of various diseases. Among Panchakarma therapies, Basti is a special treatment where it has both preventive and curative perspectives. Basti described as Ardha Chikitsa by Acharya Charaka and also as Poorna chikitsa by other Acharyas. When used properly it promotes Physical strength, Life span, Immunity and Complexion. Among various types of Basti, Niruha Basti is important type described by all Acharyas. The present article is an attempt to compile information about Role of Niruha Basti in different conditions and few of the Niruha Basti Yogas according to Charaka Samhita.