bluuebunny/crossref_metadata_2025 huggingface dataset:
Пространственная неравномерность и неоднородность инновационной деятельности США
Authors: В. Н. Минат
Published: November 2024

Предметом исследования выступает пространственно неоднородная инновационная деятельность, осуществляемая на региональном уровне США. Анализ и оценка этой деятельности проведены при помощи индикаторов рейтингования инновационного развития и интегральных показателей уровня инновационного потенциала и международного инновационного сотрудничества региональных инновационных систем конкретных штатов. Высокая корреляционная зависимость и взаимосвязь названных показателей в сочетании с показателями инновационной экономики штатов США позволили обосновать пространственную неравномерность инновационной деятельности указанных систем и дать оценку интеграции и, в то же время, разноуровневой дифференциации этих систем, в условиях неоднородности инновационного пространства Соединенных Штатов, соответствующей «центр-периферийному» принципу. Итоговая типологическая группировка региональных инновационных систем штатов США, выполненная на основе логарифмически нормального распределения средних значений показателей за период 2015-2019 гг., результирует их качественное разнообразие, отражающее пространственную неравномерность и неоднородность, как экономические феномены, определяющие инновационную деятельность США

The subject of the research is the spatially heterogeneous innovation activity carried out at the regional level in the United States. The analysis and assessment of this activity was carried out using indicators of rating of innovative development and integral indicators of the level of innovative potential and international innovative cooperation of regional innovation systems of specific states. The high correlation dependence and interconnection of the above indicators in combination with the indicators of the innovation economy of the US states made it possible to substantiate the spatial unevenness of the innovation activity of these systems and to assess the integration and, at the same time, the different-level differentiation of these systems, in the context of the heterogeneity of the innovation space of the United States, corresponding to the «centre-peripheral» principle. The final typological grouping of regional innovation systems of the US states, based on the log-normal distribution of the average values of indicators for the period 2015-2019, results in their qualitative diversity, reflecting the spatial unevenness and heterogeneity as economic phenomena that determine the innovative activity of the United States
Паттерны коммерциализации результатов прикладных исследований и разработок, финансируемых государством
Authors: В. Б. Михайлец , И. В. Радин , И. С. Соцкова , Д. П. Федулкин , Е. В. Чечеткин
Published: November 2024

Рассмотрены меры государственной научно-технической политики, оказавшие влияние на реализацию федеральной целевой программы «Исследования и разработки по приоритетным направлениям развития научно-технологического комплекса России на 2014-2021 годы» и коммерциализацию её результатов. Приведены промежуточные итоги коммерциализации результатов прикладных научных исследований и экспериментальных разработок программы. Проведен анализ зависимостей объемов коммерциализации результатов научно-технической деятельности от объемов финансирования исследований и разработок, в ходе которых эти результаты получены. Представленные сведения могут быть учтены при подготовке и планировании государственных программ поддержки науки и технологий

The measures of the state scientific and technical policy that influenced the implementation of the federal target program «Research and Development in priority areas of development of the scientific and technological complex of Russia for 2014-2021» and the commercialization of its results are considered. The interim results of the commercialization of the results of applied scientific research and experimental development of the program are presented. The analysis of the dependence of the volume of commercialization of the results of scientific and technical activities on the amount of funding for research and development, in the course of which these results were obtained, is carried out. The information provided can be taken into account in the preparation and planning of state programs to support science and technology
Этапы развития технологий искусственного интеллекта и уточнение терминологии
Authors: С. М. Евсеенко
Published: November 2024

После утверждения Национальной Стратегии развития искусственного интеллекта (ИИ) в Российской Федерации (Стратегия) были разработаны дополнительные рекомендации о включении в программы инновационного развития (ПИР) акционерных обществ с государственным участием (АОсГУ) мероприятий и проектов по внедрению технологий ИИ в процессы производства и выпускаемую продукцию. В статье кратко представлены и сравнимы основные принципы и задачи в области развития технологий ИИ американской инициативы и Стратегии России. Рассмотрена эволюция развития технологий ИИ и предпосылки появления национальных стратегий по ИИ. Особое внимание в Стратегии уделено не знаниям, а данным и разметке данных. Все технологии разметки данных объединяет то, что они позволяют превратить данные в информацию. Однако, интеллектуальный процесс есть взаимодействие мыслительного и познавательного процессов, это взаимодействие имитируется и усиливается в интеллектуальных системах - партнерских человеко-машинных системах. Эти системы не заменяют человека, а являются мощным инструментом в науках о жизни и социальном поведении (в том числе в управлении и медицине), в которых знания слабо формализованы, а данные можно структурировать. Разработка нового поколения опережающих мировой уровень систем поддержки принятия решений требует мобилизации всех сил и возможностей той части интеллектуальной элиты России, которая работает в этой области

After the approval of the National Strategy for the Development of Artificial Intelligence (AI) in the Russian Federation (Strategy), additional recommendations were developed for events and projects related the implementation of AI technologies in production processes and manufactured products to be included in the innovation development programs (IDP) of joint-stock companies with public ownership (JScPO). The article briefly presents and compares the main principles and goals in the development of AI technologies proposed by the American initiative and the Strategy of Russia. The evolution of the AI technologies development and the background causes for national strategies on AI to appear have been examined. Particular attention in the Strategy is paid not to knowledge itself, but to data and data labelling. All data labelling technologies are united by the fact that they assist to turn data into information. However, the intellectual process is the interaction between mental and cognitive processes; this interaction is imitated and enhanced in the intelligent systems - partnering human-machine systems. These systems do not replace humans, but are powerful tools in life and social behavior studies (including management and medicine), where knowledge is poorly formalized and data can be structured. The development of a new generation of decision support systems to be ahead of the world level requires the mobilization of all the forces and capabilities of all Russian intellectual elite working in this sphere
Третья составляющая Университета Гумбольдта
Authors: К. О. Беляков
Published: November 2024

Третья миссия Университета - как влияние университета на развитие общества, регион, создание новых смыслов и технологий - как перейти от модели - образа Третьей миссии к модели - проектной деятельности реализации третьей миссии? В статье определены тактические шаги, чтобы появилась третья составляющая университета к имеющимся двум в структуре классической немецкой схеме Университета Гумбольдта - создающая механизм реализации третьей миссии университета. Подробно описаны и структурно показаны, как и какие составляющие должны быть созданы в университете для реализации предпринимательского трека. Формирования университета как создателя высококлассных специалистов, молодых ученых, предпринимателей и управленцев

The third mission of the University - how is the influence of the university on the development of society, the region, the creation of new meanings and technologies - how to move from the model-image of the third mission to the model-project activity of the implementation of the third mission? The article defines the tactical steps for the emergence of the third component of the university to the existing two in the structure of the classical German scheme of the Humboldt University - creating a mechanism for the implementation of the third mission of the university. It is described in detail and structurally shown how and what components should be created at the university for the implementation of the entrepreneurial track. Formation of the university as a creator of highly qualified specialists, young scientists, entrepreneurs and managers
Стратегический бенчмаркинг зрелости в области трансфера технологий отечественных высших учебных заведений и научных организаций
Authors: И. В. Рождественский , А. В. Филимонов , А. С. Хворостяная
Published: November 2024

Данная статья базируется на исследовании, проведенном Национальной ассоциацией трансфера технологий в 2021 г. и посвященном анализу рынка трансфера технологий. В статье приведены результаты анализа зрелости процессов в области трансфера технологий высших учебных заведений и научных организаций по разработанной методологии. Полученные выводы могут быть использованы отечественными высшими учебными заведениями и научными организациями для понимания своих конкурентных преимуществ

This article is based on a study conducted by the National Association of Technology Transfer in 2021, dedicated to the analysis of the technology transfer market. The article presents the results of the analysis of the maturity processes in the technology transfer field of higher educational institutions and scientific organizations according to the developed methodology. The obtained conclusions can be used by domestic higher educational institutions and scientific organizations to understand their competitive advantages
Пути снижения рисков венчурного инвестирования
Authors: С. А. Красильников , А. С. Красильников
Published: November 2024

Рассматриваются методы снижения рисков венчурного инвестирования, включающие снижение рисков как на этапе отбора проектов, так и на этапе их финансирования. Особое внимание уделяется механизму инвестиций в скейлапы (scaleups) - быстрорастущие технологические компании, уже продемонстрировавшие возможности быстрого роста выручки. Предлагаемая методика позволяет оптимизировать количество учитываемых критериев отбора проектов при одновременном снижении рисков их финансирования

Methods of reducing venture funding risks both at the projects selection stage and financing stage are considered. Special attention is paid to the mechanism of investing into scaleups - fast growing technological companies, which have already shown capabilities for quick growth of revenue. The authors propose framework, which allows to optimize the number of criteria employed for projects selection with simultaneous reduction of their funding risks
Material sustainability evaluation of electrocatalysts in early-stage development
Authors: Heymann Lisa , Schreiber Andrea , Pithan Christian , Baeumer Christoph , Gunkel Felix
Published: November 2024

Sustainable energy materials for energy storage applications are crucial for a reliable energy transition. However, evaluating material sustainability in early stages of energy material research is a big challenge, as it is difficult to predict the final industrial process and supply chain of the investigated material. In this work we showcase that a sustainability evaluation can already be conducted in the early stage of electrocatalyst research. We provide a case study of two highly active alkaline oxygen evolution catalysts La0.6Sr0.4CoO3-δ and La0.6Ca0.4FeO3-δ with a thin film model catalyst approach. For the sustainability evaluation, we consider the material criticality, compare precursor prices, conduct an environmental impact analysis of the precursors based on life cycle assessment and provide a qualitative discourse for social impacts of raw material extraction. We find that La0.6Ca0.4FeO3-δ has a reduced environmental footprint, smaller precursor supply risk and 10 times lower precursor price compared to La0.6Sr0.4CoO3-δ. However, for both perovskites the high environmental impact and high supply risk of lanthanum is of immediate concern towards larger scale application purposes. Sustainability evaluation in the early stages of energy material research can be a great chance to develop new material selection strategies leveraging sustainability in later stages of materials research for the energy transition.
The role of Ukrainian healthcare in the global market of medical services: growth factors in the context of globalization
Authors: Каminska Т.М. , Оleksiuk О.B. , Komorovsky R.R. , Hladkykh F.V.
Published: November 2024

Background. Post-war recovery in Ukraine necessitates rapid economic and social development, including in the healthcare sector. The quality of life and active participation in society are highly dependent on robust health, especially for citizens affected by physical and psychological trauma due to the russian aggression.

Purpose – to explore the potential for exporting medical services from Ukraine and attracting international patients.

Materials and Methods. Review of the literature on the development of global medical services and healthcare markets; analysis of statistical data on the state and capabilities of Ukraine’s healthcare sector; study of best practices from other countries in the field of medical tourism; assessment of economic indicators and their correlation with the growth of international medical services.

Results. The study reveals that Ukraine has significant potential to develop its international medical services sector. This potential is driven by the high qualifications of Ukrainian doctors, the relatively low cost of medical services, and the availability of advanced medical technologies in some hospitals. Promoting international medical services can attract foreign investment, enhance the quality of healthcare, and generate substantial economic benefits. The influx of international patients would generate export revenues, contributing to the state budget and balancing the national payment system. However, challenges such as infrastructure improvements, international accreditation, and effective marketing need to be addressed to fully realize this potential.

Conclusions. Developing international medical services in Ukraine can significantly enhance the national economy and healthcare system. Strategic focus on this sector can yield benefits like improved healthcare quality, increased foreign investment, and significant economic returns. Addressing challenges and leveraging the country’s strengths in healthcare are essential for success.
Relationship Between Pitch Velocity and Physical Fitness in Elite Baseball Pitchers
Authors: Yang Zhigang , Wang Lina
Published: November 2024

The purpose of this study was to determine the key physical conditions needed for a pitcher by studying the relationship between pitch velocity and a set of selected physical fitness variables. Seventeen baseball coaches and experts were recruited to recommend and select key variables determining pitchers’ physical fitness. After a three-round inquiry, 16 variables were identified. Internal consistency reliability (Cronbach’s α reliability) was 0.826 and the content validity ratio was 1. A total of 27 male elite baseball pitchers (22.97±4.01 years old), who came from Chinese professional teams, were tested by the 16 variables selected and their pitch velocity was determined after warm-up. The correlations between pitch velocity and the other 15 variables were computed. The coefficient of the correlation among pitch velocity and max distance long toss, jump lunge with load, and shoulder internal rotation was 0.628 (p<.05), 0.369 (p<.05), and -0.312(p<.05), respectively. A follow-up regression analysis found that three variables explained 42.9% of the pitch velocity variance. The pitch velocity was moderately related to their max distance long toss and somewhat correlated with jump lunge with load and shoulder internal rotation.
Damage assessment and relocation as tools for preserving business during martial law
Authors: Panchenko Volodymyr , Hrabchuk Iryna
Published: November 2024

The article is devoted to studying the problems of damage assessment and business relocation under martial law in Ukraine. The article uses literature and document analysis methods, including a review of recent studies on damage assessment and business relocation and an analysis of relevant legal acts and international standards. The authors examine the legal framework governing the process of assessing the damage caused by armed aggression and the mechanisms for compensating it.The methodological aspects of evaluation, including standardised and independent approaches, are analysed, emphasising the importance of adherence to national and international standards. The main stages of the valuation process are described: preparation, actual valuation, and report. Particular attention is paid to the problems of accounting for changes in the value of money over time and regional differences in economic conditions. The article examines the role of international organisations and standards in ensuring transparency and reliability of damage assessment. The importance of establishing the International Register of Losses in The Hague as an important tool fordocumenting losses and ensuring accountability for armed aggression is emphasised. Particular attention is paid to the issues of business risk insurance in wartime and investment insurance against war risks. The role of such organisations as the Multilateral Investment Guarantee Agency in supporting the investment climate in Ukraine is analysed. The importance of effective damage assessment and business relocation as key tools for maintaining economic stability, minimising losses and preserving the potential for future recovery and development of Ukraine under martial law isemphasised. The need to further improve the methodology for assessing losses and compensation mechanisms to ensure fair compensation and increase confidence in the country's economic recovery process is highlighted.
A Case Report of Disseminated Nocardiosis
Authors: Pang Rong , Wang Lingwei
Published: November 2024

Objective: To summarize the clinical characteristics and treatment plan for a case of disseminated nocardiosis. Methods: The study summarized the clinical characteristics and treatment plan for a case of disseminated nocardiosis. Results: The primary symptoms of the patient included high fever and multiple enlarged lymph nodes. Chest computed tomography revealed a shadow of nodules in the upper lobe of the left lung, multiple nodules, and pleural effusion in both lungs. Additionally, bilateral blood cultures indicated the presence of Nocardia terpenica. The final diagnosis was disseminated Nocardia sp. infection. Upon admission, anti-infective treatment was initiated with sulfamethoxazole and linezolid. Conclusion: In patients with normal immune function, disseminated nocardiosis may present as high fever with lymph node enlargement, necessitating differentiation from lymphoma. This study reports on the diagnosis and treatment plan of a case of disseminated nocardiosis to enhance understanding and clinical management of this disease.
Enfermería en Urgencias y Emergencias
Authors: Guaña Bravo Elena Silvana , Arandi Quinto Ana Belén , Solórzano Zambrano Gloria , Chóez Loor Sandra Karina , Salvatierra Chica Richard José , Galardy Domínguez Yelennis , Vite Macías Franklin Daniel , Lucas Flores Luisa Yessenia , Álava Rengifo Nidia Narcisa , Mendoza Mendoza Liliana Mirella , Zambrano Cevallos Juliana , Zambrano Valenzuela Cristhian Fabricio , Cobos Espinoza Vanessa Lizbeth , Tamayo Miranda Mónica Elizabeth , Mero Carreño Ana María , Ferrìn Zambrano Eilen Dayana , Vélez Cuenca María Felicidad , Genovesi Anguizaca Gabriela Beatriz , Rivera Solís Kevin Xavier , Jordán Zamora Margarita Lissette , Cerezo Leal Betzaida Salomet , Moreno Cobos María de los Ángeles , Menéndez Pin Tania del Rocío , Macías Alvia Aida Monserrate , Lucas Choez Mercedes María , Quiroz Villafuerte Viviana Marianella , Orellana Suarez Kleber Dionicio , Muñiz Granoble Gloria , Hurtado Delgado Jonathan Xavier , Cusquillo Guamán Oscar Lenin , Paz Trujillo Joselyn Briggitte , Vite Solórzano Franklin Antonio , Ochoa Anastacio María Elena , Vintimilla López Elva Faviola , Cevallos Tapia Ana del Rocío , Narváez Bastidas Diana Elvira , Rodríguez Díaz Jorge Luis , Farfán Vélez Leonela Carolina , Mosquera Plúa Letty Karina
Published: November 2024

En la actualidad, la atención a personas sanas o enfermas han sido desplazados hacia un enfoque más técnico y administrativo, acompañado de cuestiones institucionales como brechas negativas, demandas y cargas de trabajo, doble trabajo, agotamiento físico y mental, condiciones de trabajo y salarios inadecuados. y la creencia de algunas enfermeras de que sólo la tecnología puede ayudarlas a desarrollarse profesionalmente.
Las personas suelen confundir los términos “emergencia” y “atención de urgencia”, pero hay una cosa clave que los diferencia, y es importante saberlo para definir ambos conceptos. La misión principal del servicio de urgencias es valorar y dar respuesta a emergencias y urgencias, brindando atención a los pacientes que requieran atención urgente. El objetivo principal de este documento es determinar la incidencia de procesos y enfermedades que se tratan principalmente en los hospitales.
Este libro, presenta consideraciones sobre la naturaleza del cuidado prestado por profesionales de enfermería desde el punto de vista teórico y práctico, enfatizando la importancia de la visualización oportuna de estos elementos, ligados intimarte al quehacer de la atención enfermera. La reflexión es para los enfermeros que trabajan a diario con los usuarios del sistema de salud, especialmente en el área de urgencias y emergencias médicas y necesitan de sus cuidados.
Este manuscrito, que te presentamos, pretende resumir, las características generales de los fundamentos de la enfermería en emergencia y urgencias, está escrita con dedicación, seriedad, soltura y comodidad en un lenguaje claro y conciso, dirigido principalmente a estudiantes y docentes.
Potential Risks from Cannabis- Infused Beverages: A Critical Review
Authors: Froude Anna Marie , Pangborn Nikki , Britz-McKibbin Phillip , MacKillop James , Balodis Iris
Published: November 2024

Although Canada legalized cannabis beverages in 2019, most available research on acute cannabis
intoxication derives from dried flower and edible products. The distinct bioavailability and pharmacokinetic
properties of phytocannabinoids ingested from beverages, however, contribute to significantly different
acute and long-term effects that need to be better understood to ensure consumer safety. Objective: This
review investigates existing cannabis beverage literature, with a particular focus on acute intoxication
effects. Method: PubMed, PsycINFO and Web of Science databases were systematically searched. A
structured search generated 29 eligible studies, comprising studies of consumption patterns and beliefs,
advertisements and marketing, acute effects in human models, and drink composition. Results: Human
studies report aversive acute subjective and physiological effects induced by cannabis beverages in healthy,
infrequent users. Beverages also showed inaccurate cannabinoid labeling, posing potential risks to
consumers. This review highlights the paucity and inconsistency of available research, further exacerbated
by the sheer diversity of formulations investigated, while beginning to address some questions surrounding
the safety and risks associated with cannabis beverages. Conclusions: Given the extensive differences in
effects across cannabis-infused beverages, and the growing ‘drinkables’ market, it is essential that more
studies directly examine both acute and long-term impacts of cannabis beverage consumption.
ALTERNATIVA METODOLÓGICA PARA EL APRENDIZAJE DE LA MATEMÁTICA CON APOYO DEL SOFTWARE GEOGEBRA
Authors: Sampedro Luna Estefanía Tatiana , Sarmiento Segovia María José
Published: November 2024

El estudio se centra en el desarrollo de una alternativa metodológica para el aprendizaje sobre las derivadas aplicadas en el proceso educativo que permita a los estudiantes universitarios enriquecer su conocimiento y tener un aprendizaje significativo, utilizando herramientas tecnológicas como el software GeoGebra. El problema de la investigación es el poco conocimiento y atención por el estudiantado con respecto al desarrollo de las derivadas exponenciales. El objetivo de este estudio es presentar una alternativa metodológica para el aprendizaje de las derivadas de funciones exponenciales en donde jóvenes estudiantes desarrollen habilidades y destrezas que permitan una fácil comprensión de la matemática. La investigación es de tipo descriptiva, con enfoque cuantitativo, los métodos desarrollados son el inductivo y el analítico sintético. Los resultados obtenidos demuestran que el software GeoGebra es una herramienta muy importante y dinámica para el aprendizaje y enseñanza de las matemáticas en cualquier ámbito ya sea álgebra, geometría, estadística y cálculo, permitiendo a los estudiantes desarrollar grandes destrezas.
Tracing the imperial roots of cassava in Mozambique: production, trade and consumption of a food commodity
Authors: Rodrigues Eugénia
Published: November 2024

Drawing upon qualitative analyses of Portuguese sources, this article explores the cassava trajectory in modern-day Mozambique between the mid-18th and mid-19th centuries within the framework of the trans-imperial networks in the Indian Ocean World. It begins by addressing the possible routes of introducing the plant across Mozambique’s territory and the colonial policies aimed at making its cultivation mandatory. It demonstrates how this process unfolded amidst intense conflicts between the Portuguese colonial administration and the landholders, while the Africans resisted consuming cassava. Then, it analyzes the systems for growing cassava in plantations and processing the root for consumption, from flour mills to sun-drying techniques, using slave labour. Finally, it argues that cassava production was initially based on supplying the army and only later was driven by the slave trade, thus demonstrating the role this food commodity played in building the Portuguese empire in the Indian Ocean.
PERSONAL IS POLITICAL: GESTURES OF SOLIDARITY FROM THE MOTHER FOREST AND CHENGARA
Authors: Scaria Dimple M.
Published: November 2024

The paper attempts to perceive how the land takes possession of some social and political proportions and how this socially and politically reframed land turns out to be a premise through which relationships of dominance and subordination get operated and hierarchies maintained. The study takes up the issues of land, caste and the individual to substantiate the point that geographical space invariably proves to be a socially created reality rather than a sheer physical structure. The life narratives of C. K. Janu and Seleena Prakkanam bear testimony to it. It is very pertinent and appropriate to study these life narratives due to the inextricable link between caste and land in shaping the narrative experience of these women with seldom receptiveness in the so-called highbrow discourses.
Pengenalan Paket Teknologi Budidaya Jagung pada Kelompok Tani Karya Tani Dusun Batu Gembung Kabupaten Lombok Utara
Authors: I Wayan Sudika  , I Wayan Sutresna  , Dwi Ratna Anugrahwati  , Ni Wayan Sri Suliartini  , I Gusti Made Kusnarta
Published: November 2024

Kelompok tani Karya Tani dusun Batu Gembung memiliki masalah kurangnya pengetahuan dan keterampilan teknik budidaya menggunakan sistem tanam jajar legowo yang dikombinasikan dengan pupuk organik serta saat pemupukan anorganik. Oleh karenanya, pengabdian ini bertujuan meningkatkan pengetahuan dan keterampilan di bidang karakteristik tanaman jagung umur super genjah dan sifat stay-green, teknik budidaya jagung lahan kering dengan menggunakan benih jagung komposit Sinta Unram dan teknik pembuatan benih jagung komposit. dan mengetahui perbedaan hasil jagung dengan paket yang diperkenalkan dibanding hasil jagung cara petani. Metode pendidikan orang dewasa dengan teknik partisipatif digunakan dalam pengabdian ini, yakni melalui demplot. Dalam demplot diterapkan dua paket, yaitu paket I (teknologi yang diperkenalkan) dan paket II (cara petani). Data yang diamati pada demplot, meliputi tinggi tanaman, jumlah daun, diameter batang, jumlah tongkol per plot, panjang tongkol, diameter tongkol, bobot tongkol kering panen per plot, dan hasil (bobot biji kering pipil per plot. Uji t digunakan untuk pengujian kedua paket tersebut. Hasil pengabdian menunjukkan bahwa terjadi peningkatan pengetahuan dan keterampilan di bidang karakteristik tanaman jagung umur super genjah dan sifat stay-green, teknik budidaya jagung lahan kering dengan menggunakan benih jagung komposit Sinta Unram dan teknik pembuatan benih jagung komposit sebesar 32,23 persen. Petani telah mengenal paket teknologi budidaya tanaman jagung lahan kering akibat adanya demplot. Hasil tanaman jagung lebih tinggi dengan teknologi yang diperkenalkan dibanding cara petani berturut-turut sebesar 4,202 kg per plot (7,503 t/ha) dan 2,182 kg per plot (3,896 t/ha) dengan peningkatan sebesar 92,59 persen. Teknik ini perlu diperkenalkan di kelompok tani lain yang memiliki lahan kering.
Exploring Environmental Neurotoxicity Assessment Using Human Stem Cell-Derived Models
Authors: Narimane Kebieche , Farzana Liakath Ali , Seungae Yim , Mohamed Ali , Claude Lambert , Rachid Soulimani
Published: November 2024

Neurotoxicity is increasingly recognized as a critical factor impacting long-term health, with growing evidence linking it to both neurodevelopmental and neurodegenerative diseases. Pesticides, widely used in agriculture and industry, have emerged as significant contributors to neurotoxic risk, given their capacity to disrupt key neurodevelopmental processes at low exposure levels. As conventional animal models present limitations in interspecies translation, human-derived neuron-based in vitro screening strategies are urgently needed to assess potential toxicants accurately. Human-induced pluripotent stem cells (hiPSCs) offer an innovative and scalable source for human-specific neuronal models that complement traditional animal-based approaches and support the development of predictive assays for neurotoxicity. Recent various stem cell models, including 2D cultures, 3D organoids, and microfluidic systems, are now available, advancing predictive neurotoxicology by simulating key aspects of human neural development and function. With the integration of High-Throughput (HT) and High-Content (HC) screening methodologies, these hiPSC-based systems enable efficient, large-scale evaluation of chemical effects on neural cells, enhancing our ability to detect early biomarkers of neurotoxic effects. Identifying early biomarkers of neurotoxic is essential to developing therapeutic interventions before irreversible damage occurs. This is particularly crucial in the context of developmental neurotoxicity, where early exposure to toxicants can have lifelong consequences. This review specifically presents an in-depth overview of the current progress in hiPSC-derived neural models and their applications in neurotoxicity testing, with a specific focus on their utility in assessing pesticide-induced neurotoxicity. Emphasizing future research priorities, we highlight the potential of these models to transform predictive toxicology, offering more human-relevant assessments and advancing the field toward a more precise evaluation of environmental neurotoxicants.
Effective teaching, teacher-student relation, student engagement and student mathematical achievement
Authors: Chui Hong Sheung , Chui Samuel Wing Ho
Published: November 2024

This study tries to investigate the effects of effective teaching of mathematics on teacher-student relationship (TSR), student engagement (StEn) and student mathematical achievement. A questionnaire is developed to measure the above three constructs in this study, and examination results at the end of the academic year are obtained as the measure of achievement. Confirmatory factor analysis shows that the constructs measured by the questionnaire have reliability and validity. Structural equation modelling confirms the proposal that effective teaching will affect TSRs, StEn, and mathematical examination scores. Teaching effectiveness as measured by students’ responses to the questionnaire can account for 14% of the variance of students’ final examination score. This study may shed light on the causal effects of effective teaching on TSR, StEn and mathematical achievement. Findings of this study may inform teachers of approaches in teaching to enhance students’ achievement in mathematics.
Efectos de la configuración de áreas forestales sobre la comunidad de murciélagos insectívoros en paisajes agroforestales.
Authors:   , Vilches Piñones Karol
Published: November 2024

El estudio examinó la ecología y distribución de murciélagos en Chile en la región de Temuco Valle Central de La Araucanía, destacando la importancia de la configuración del paisaje en la organización territorial para el buen manejo de la biodiversidad. Se enfocó en dos paisajes (homogéneo vs. heterogéneo). Utilizamos 4 transectos de 10 km con 10 puntos de escucha para realizar un análisis de la actividad de los murciélagos insectívoros, repitiendo cada transecto 5 veces. Los resultados revelaron que el paisaje heterogéneo estaba dominado por Tadarida brasiliensis, mientras que el homogéneo por Lasiurus spp. Solo Tadarida brasiliensis se vio afectada por el tipo de paisaje, con respuestas positivas para bosques nativos y mixtos, y negativas para plantaciones. La densidad de árboles aislados afectó la actividad de Tadarida brasiliensis y Lasiurus spp., para los paisajes homogéneos. Se concluyó que considerar elementos del bosque en paisajes agroforestales es crucial para conservar comunidades de murciélagos y aprovechar sus servicios ecosistémicos para la conservación a largo plazo en la Araucanía, Chile.
Green marketing in Central Europe: Consumer perceptions and purchase intentions between 2010 to 2023
Authors: Jinyoung Hwang
Published: November 2024

This study investigates the evolution of green marketing in Central Europe, emphasizing consumer perceptions and purchase intentions from 2010 to 2023. It explores the impact of economic and social transformations in countries like Poland, Czech Republic, Hungary, Slovakia, and Austria, focusing on the growing prominence of sustainability in consumer behavior. By employing a mixed-method approach, the research examines how green marketing strategies, such as eco-labeling and corporate social responsibility initiatives, influence consumer attitudes and purchasing decisions. The study also identifies key drivers shaping environmentally conscious behavior, including trust, transparency, and perceived social and environmental benefits. The findings underscore the critical role of policies, economic incentives, and cultural dynamics in fostering sustainable consumption. This research provides actionable insights for businesses and policymakers aiming to align with the region’s sustainability goals while addressing broader environmental challenges. Through a blend of quantitative data and qualitative interviews, it contributes to the theoretical and practical understanding of green marketing’s trajectory, offering a roadmap for effectively engaging with eco-conscious consumers in Central Europe.
Innovative pricing strategies in the digital age: A case study of fashion E-commerce Companies in China
Authors: Jinyoung Hwang
Published: November 2024

The research explores innovative pricing strategies in China’s fashion e-commerce sector, focusing on their impact on consumer behavior, revenue growth, and market competitiveness. By analyzing techniques such as dynamic pricing, personalized discounts, subscription models, and flash sales, the study uncovers how digital technologies and data analytics optimize pricing frameworks. The integration of AI-driven algorithms and social commerce platforms highlights the sector's adaptability in leveraging technology to influence consumer decisions and boost profitability. A case study approach investigates how fashion e-commerce companies address challenges such as fluctuating demand, market competition, and ethical considerations in pricing. The research also examines consumer perceptions, emphasizing trust, transparency, and the psychological impact of urgency and exclusivity. Findings provide actionable insights for businesses navigating the rapidly evolving digital marketplace. This study not only enhances understanding of pricing strategies but also contributes to broader discussions on the intersection of technology, consumer behavior, and economic growth in the e-commerce landscape.
Model order reduction for the cross-diffusive Brusselator Equation
Authors: Tuğba Küçükseyhan
Published: November 2024

The cross-diffusive Brusselator equation is a reaction-diffusive system that models complex chemical and biological process with both self-diffusion and cross-diffusion effects. These equations exhibit rich spatiotemporal dynamics, including Turing patterns and instability-driven pattern formations. Despite its significance, the computational cost of solving high-dimensional discretized versions of the cross-diffusive Brusselator equation can be prohibitive, particularly in parameter-dependent or long-time simulations. This study presents a model order reduction (MOR) framework tailored to the Brusselator equation, leveraging Proper Orthogonal Decomposition (POD) combined with Galerkin projection along with the Discrete Empirical Interpolation Method (DEIM) and the Dynamic Mode Decomposition Method (DMD) to efficiently approximate nonlinear dynamics. The reduced models are constructed to preserve key features of the original system, including stability and accuracy, while achieving substantial computational savings. Numerical experiments validate the proposed approach, demonstrating its effectiveness in capturing the essential dynamics of the Brusselator equation under various parameter settings. These findings provide a robust pathway for efficient simulation and analysis of reaction-diffusion systems in scientific and engineering applications.
In Vitro evaluation of some fungicidal bioactive chemicals against fusarium spore germination and survival
Authors: Salith H.S  , Ezeofor A.O  , Hassan S.A  , Abdul-Hadi J.S  , Iweajunwa S.O  , Onwuzulike A.N  , Odi-Akpa C.V
Published: November 2024

The genus Fusarium are the most important pathogens associated with different plants including crop plants, fruits, vegetables, etc. causing of constrained production and productivity crops. Bioactive compounds are environmentally friendly and amenable. This study aimed to evaluate the effectiveness of some bio-active compounds derived from Bacillus strain for the in vitro control of Fusarium mold. Seven (7) isolates of the Fusarium complex were isolated from various stored fruits, vegetables and food grains using Potato Dextrose Agar (PDA) media supplemented with antibacterial agent. The growth and survival of the respective spores were challenged with supernatants of overnight-grown culture of Bacillus subtilis TC17 for 20 minutes. The supernatant prevented the germination of spores of some fungi strains in the order; F. solani, F. oxysporum, F. equiseti, F. acuminatum, F. proliferatum, F. moniliforme and F. tricinctum against control. Therefore, this research showed that the bio-active agent can be used to control the pervasive plant pathogenic fungal species with outstanding result and therefore should be developed further for registration for commercial applications.
Immunological therapies targeting leukemia
Authors: Cynthia Nayeli Quezada Ayala  , Daniela Córdova Treviño  , Eymmy Elizabeth Rangel Payan  , Fernanda Zairemg Contreras García  , Brissia Lazalde  , Jesús Ernesto Landeros Yescas
Published: November 2024

Leukemia represents one of the greatest challenges in medical oncology due to its aggressiveness and biological complexity. Immunotherapy has recently emerged as a promising option for the treatment of leukemias, however, its genetic complexity has represented a challenge for it. ALL and AML present different genetic alterations, such as mutations, chromosomal rearrangements and signaling pathways. Currently, several therapies have been investigated and applied to try to treat leukemia, among them, CAR T-cell therapy has shown great effectiveness, monoclonal antibodies are another promising option, several immune checkpoint inhibitors have also been developed, the use of CAR-NK cells offers another promising alternative, and as usual, stem cell transplantation remains an important curative option. Leukemia treatments continue to be renewed and updated to make them less toxic and less aggressive for patients.
Optimalisasi Preventive Maintenance Ground Power Unit pada Perawatan Pesawat Udara di PT. IAA AMO Menggunakan Metode FMEA
Authors: Kurniawan Sandi , Apriliana Sari Wulandari Indah , Sukmono Tedjo
Published: November 2024

High operational costs and downtime risks can affect industry efficiency making equipment maintenance optimization an urgent need. PT. IAA AMO, as a manufacturing industry in the field of aircraft maintenance, faces significant challenges with the low reliability of Ground Power Unit (GPU) engines which only reaches 86%. This has led to an increase in the company's operating costs. The purpose of this study is to optimize Preventive maintenance on the Ground Power Unit (GPU) in aircraft maintenance at PT. IAA AMO using the Failure Mode and Effect Analysis (FMEA) method. The results show that the MTTF of the GPU is 311 hours, while the MTBF is 373 hours. To prevent  sudden breakdowns, preventive maintenance is recommended every 311 hours for non-repairable components  and 373 hours for repairable components. This research offers a more effective maintenance strategy to improve GPU reliability and lower operational costs. This research results in more effective maintenance planning, which not only minimizes downtime and operational costs, but also improves the overall reliability of the GPU machine. With the implementation of FMEA methods and  the right preventive maintenance  strategy, companies can anticipate breakdowns early, extend engine life, and ensure smooth operations in support of aircraft maintenance.
Analisis Kelayakan Finansial dan Prospek Pertumbuhan Usaha Pengolahan Rumput Laut di Desa Jang
Authors: Indah Asmarawati Citra , Hidayat Fizy
Published: November 2024

Jang Village, located in Moro District, Karimun Regency, has abundant seaweed resources utilized for various products, including collagen drinks. This study aims to analyze the financial feasibility of seaweed processing using parameters such as Net Present Value (NPV), Internal Rate of Return (IRR), Payback Period (PP), and Break Even Point (BEP). The analysis results indicate that the BEP is 1.236 units, with a BEP in Rupiah of Rp6.946,00, an NPV of Rp195.869.079,29, an IRR of 21%, and a PP of 4.4 months. Based on the evaluation of financial and non-financial aspects, the seaweed processing business run by CV. Moro's Pure Marine Collagen is considered feasible and profitable. The findings of this study are used to develop long-term business strategies, including global market expansion supported by digital marketing and product diversification such as sports supplements and skincare products. Competitive advantage is enhanced through product certification and continuous research. Business sustainability is achieved by implementing environmentally friendly practices and empowering coastal communities, which is expected to support local economic growth and maintain the sustainability of natural resources.
Emotionale Erfahrung im Hier-und-Jetzt
Authors: Will Herbert
Published: November 2024

In dieser Arbeit wird der Einfluss untersucht, den Sándor Ferenczi auf das Verständnis der psychoanalytischen Situation nimmt. Zusammen mit Rank macht er sie in den Entwicklungszielen von 1924 zu einem Basiskonzept der Psychoanalyse. Freud hatte mit der analytischen Situation die Rahmenbedingungen der Sitzung und die Übertragung zusammengefasst. Rank engt sie auf die Reproduktion und Auflösung des Geburtstraumas ein, während Ferenczi für eine Öffnung des Konzepts sorgt. Er legt besonderen Wert auf die emotionale Erfahrung im Hier-und-Jetzt und auf die wechselseitigen Einflüsse des analytischen Paares. Die Positionierungen M. Kleins und L. Stones werden beschrieben. Die Arbeit kommt zu dem Schluss, dass Ferenczis Auffassung von der analytischen Situation in vielen Hinsichten die psychoanalytische Feldtheorie vorwegnimmt und mit Baranger und Baranger, Bion, Ferro und Civitarese zusammen noch viel Potenzial bietet.
»Den ganzen Sommer über wollen wir in Budapest bleiben«
Authors: Römer Maximilian , Treu Peter
Published: November 2024

Anlässlich des 150. Geburtstages von Sándor Ferenczi fand im Juni 2023 die Ferenczi 150th Anniversary International Conference in Budapest statt. Der Tagungsbericht wirft kursorisch Schlaglichter auf die Vorträge und Foren der Konferenz. Nebst einer historischen Einordnung verdeutlichten die Tagungsbeiträge eindrücklich den aktuellen Einfluss des Gesamtwerkes Ferenczis auf die zeitgenössische Psychoanalyse, auch in Verbindung zu gesellschaftsund kulturwissenschaftlichen Analysen. Die Inhalte des in Budapest produktiv geführten Dialogs zwischen theoretischer und klinischer Praxis sollen hier nachgezeichnet werden.
РЕКЛАМНИЙ ВІДЕОРОЛИК ЯК СИНТЕЗ МЕДІА: УКРАЇНСЬКІ РЕАЛІЇ ВОЄННОГО ЧАСУ
Authors: ДІДЕНКО О. М.
Published: November 2024

Метою статті є огляд та аналіз практичних напрямів застосування відео- та кіно-реклами медійного характеру в умовах сучасної України, особливо в контексті дизайну та реклами. Методологія дослідження української реклами здійснена за допомогою історико-культурного підходу, що дозволило простежити її розвиток в контексті війни. Соціокультурний підхід виявив зміну наративних та візуальних стратегій, що використовувалися в рекламі, а компаративний підхід дав змогу порівняти український рекламний контент з міжнародними стандартами. У статті проведено аналіз українських рекламних та соціальних відео та кіно-роликів у контексті війни. Досліджено зміну наративних та візуальних стратегій, що використовуються для залучення аудиторії, зокрема через патріотичні та соціальні теми, а також донорські кампанії для підтримки армії та економіки. Увагу зосереджено на технологічних досягненнях у галузі візуальної культури, що дозволяє порівняти український рекламний контент із міжнародними стандартами. Стаття акцентує увагу на двох ключових аспектах: фінансування та донорство задля перемоги і підтримка українських послуг через медійну рекламу. Також розглянуто приклади сучасних українських рекламних роликів, які сприяють формуванню нових стандартів у галузі дизайну та реклами. Наукова новизна статті полягає у вперше проведеному аналізі специфіки виробництва рекламного контенту в умовах воєнного стану, що підкреслює його вплив на формування національної свідомості та підтримку економіки України. Дослідження надає нові знання молодим дизайнерам та вченим щодо використання рекламних та соціальних відео- та кіно-роликів у сучасному українському медіа- просторі, що сприяє їхньому професійному розвитку.