bluuebunny/crossref_metadata_2025 huggingface dataset:
EVALUASI KESESUAIAN LAHAN UNTUK TANAMAN BAWANG MERAH (Allium cepa L.) DI KECAMATAN MALUA KABUPATEN ENREKANG
Authors: Acksan Bryan , Tjoneng Amir , Saida Saida
Published: June 2024

The purpose of this study was to determine the actual and potential land suitability classes for Shallots and the limiting factors in Malua District, Enrekang Regency. The research was carried out from October 2021 to December 2021 in Malua District, Enrekang Regency and Soil Properties Analysis was carried out at the Laboratory of Soil and Environmental Conservation, Faculty of Agriculture, Muslim University of Indonesia. The method used in this research is the survey method and the determination of land suitability classes based on the FAO method with the approach of limiting factors/land characteristics. The results showed that the actual land suitability class on the Inceptisols and Ultisols soil types for onion cultivation was unsuitable land (N) with the limiting factor being the level of erosion hazard (eh). The potential land suitability class after improvement of the limiting factor is obtained according to the S2 (tc, rc). With the limiting factors of temperatures and textures, these limits will reduce productivity of profits.
PENGARUH KONSENTRASI DAN FREKUENSI PEMBERIAN PUPUK ORGANIK CAIR TERHADAP PERTUMBUHAN DAN PRODUKSI TANAMAN JAGUNG (Zea mays L.)
Authors: Edy Edy , Rabiaty Tira , Aminah Aminah
Published: June 2024

This study aims to determine the effect of concentration and frequency of liquid organic fertilizer on the growth and production of maize. This research started in August 2021 until November 2021. This study used a two-factor randomized block design (RAK). The first factor is the concentration of liquid organic fertilizer which consists of 3 levels, namely, without POC, 2 g/l water, 4 g/l water. The second factor is the frequency of application of liquid organic fertilizer which consists of 3 levels, namely, once a week, every 2 weeks, and every 3 weeks. Each combination was repeated 3 times so that there were 27 experimental units, the number of plant samples per plot was 5 plants. Parameters observed in this study consisted of plant height, number of leaves, male flowering age 50%, female flowering age 50%, length of ear, diameter of ear, weight of seeds per ear, production of cobs per plot, weight of 100 seeds, weight of seeds per plot and production seeds per hectare. The results of this study showed that the application of liquid organic fertilizer concentration of 4 g/l water had a good effect on the parameters of plant height, ear length, ear diameter and seed weight per ear, seed weight per plot and seed production per hectare. The frequency of giving liquid organic fertilizer once a week has a good effect on the parameters of seed weight per cob. The interaction between the application of liquid organic fertilizer concentration of 4 g/l of water and the frequency of once a week has a good effect on plant height. The suggestion of this research is to use liquid organic fertilizer with a concentration of 4 g/l of water and a frequency of once a week in the cultivation of corn.
PENGARUH KOSENTRASI ZAT PENGATUR TUMBUH ATONIK DAN TAKARAN KOTORAN KELELAWAR TERHADAP PERTUMBUHAN SAMBUNG PUCUK BIBIT KAKAO KLON 45 (Theobromae cacao L.)
Authors: Jalaluddin Jalaluddin , Sabahannur St. , Subaedah St.
Published: June 2024

Response to The Provision of Growing Regulatory Substances and Bat Droppings to The Growth of Cocoa Seed Shoots Clone 45 (Theobroma cacao L.). di Desa Beringin Jaya, Kecamatan Tomoni, Kabupaten Luwu Timur The study used a Random Design Group (RAK) with a two-factor factorial pattern. The first factor of the regulatory substance grows Atonic with a concentration of 0.1.5, 3.0 ml-1 / L of water, the second factor of bat manure fertilizer at a dose of 125, 225, 325 g-1 / plant.  The results showed that the administration of attonic-growing regulatory substances with a concentration of 3.0 ml-1 / lair obtained a faster bud appearance time of 13.33 days, as well as the provision of bat droppings.
APLIKASI PUPUK ORGANIK CAIR DARI BERBAGAI JENIS LIMBAH RUMAH TANGGA TERHADAP PERTUMBUHAN DAN PRODUKSI TANAMAN SELADA (Lactuca sativa L.) DENGAN SISTEM HIDROPONIK
Authors: Fadilla Nur , Suryanti Suryanti , Alimuddin Suraedah
Published: June 2024

This study aims to determine the effect of various types of liquid organic fertilizer on the growth and production of lettuce with the wick system method. Conducted in Kuningan Village, Wonomulyo District, Polewali Mandar Regency, West Sulawesi Province, the research was carried out in August-October 2021. This study used a completely randomized design (CRD). The data were analyzed using analysis of variance and 5% BNJ. Parameters observed were plant height, number of leaves, root length, plant fresh weight. The results of this study showed that the POC of vegetables with a concentration of 20 ml/liter of water had a very significant effect on all observation parameters including plant height with an average plant height value of 9.17cm, number of leaves with an average value of 10.21 strands, root length with an average value of 9.17cm. 26.83 cm in average and plant fresh weight with an average value of 125.56g.
Case Report of a Rare Asenapine Induced Tachycardia in a Bipolar Affective Disorder Patient with Underlying Glucose-6Phosphate Deficiency
Authors: Ahmad Tajjudin Ahmad Izzat , Hooper Jonathan
Published: June 2024

Mr. R is a 29-year-old single male with underlying Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency since childhood. He presented with elated mood for 10days prior. He had 1 prior admission because of increased agitation and being aggressive towards his family doctor. G6PD has been linked with an increased risk of developing Bipolar Affective Disorder. Asenapine is a new antipsychotic on the market, which could be used as a mood stabilizer. It has a proven benefit in treating bipolar affective disorder. This case report highlights a very rare side effect of Asenapine induced tachycardia.
Estrategias tecnológicas aplicadas a la seguridad integral de los niños de inicial
Authors: Guevara Alban Gladys Patrícia , Ronquillo Murrieta Gladys Verónica , Díaz Moreno Luisa Haydee , Guevara Alban Cristian Salomón
Published: June 2024

La seguridad integral en la educación inicial es importante para el desarrollo de los niños, abarcando protección física, apoyo emocional, interacciones sociales seguras y el uso adecuado de la tecnología. La tecnología, a través de aplicaciones educativas, plataformas interactivas y dispositivos móviles, ha transformado la educación inicial, permitiendo personalizar el aprendizaje y mejorar la seguridad integral en el aula. Este artículo investiga cómo las estrategias tecnológicas pueden mejorar la seguridad integral, mediante encuestas a docentes de educación Inicial de la parroquia Clemente Baquerizo, cantón Babahoyo, para explorar sus percepciones y prácticas actuales. El estudio está estructurado en secciones que describen las estrategias tecnológicas, la metodología de recolección de datos, los resultados de las encuestas, la discusión de estos resultados en comparación con la literatura existente y las conclusiones, que resumen los hallazgos y ofrecen recomendaciones para futuras investigaciones y prácticas educativas.
Maternal Atrioventricular Nodal Re-entrant Tachycardia During Pregnancy: Case Report
Authors: Podder Priyanka , Saha Joysree
Published: June 2024

During pregnancy, the physiological changes predispose a woman for the development of new-onset or recurrent arrhythmia. Atrioventricular nodal re-entrant tachycardia (AVNRT) is a common supraventricular tachycardia (SVT) in reproductive age of woman. Although often it is benign in nature but concerning. Electrical cardioversion is safe during pregnancy. Electrophysiological study (EPS) and Radiofrequency ablation (RFA) can be performed in selected patients. Hereby, we report a case of a woman in her second trimester of pregnancy presented with diagnosed case of AVNRT. She was monitored by multidisciplinary team. Electrocardiogram (ECG) and Echocardiogram reveals normal changes. EPS and RFA was done one year back at the time of diagnosis. At her 37 weeks of pregnancy, she developed scar tenderness. Emergency caesarean section was done in presence of cardiologist. Maternal and perinatal outcome were good.
Bangladesh Med J. 2023 Jan; 52(1): 35-38
Thyroid Collision Tumour: Concurrence of Two Thyroid Malignancy
Authors: Muhamad Zin Muhamad Hud , Hayati Firdaus , Abdullah Suhaim Shahrun Niza , Abdullah Suhaimi Shahrun Niza , Muhammad Rohaizak , Mohamad Muhammad Afiq Bin , Pauzi Suria Hayati Md , Isa Nurismah Md , Ishak Mohamed Izzad
Published: June 2024

Thyroid carcinoma is the most common endocrine malignancy. However, it is exceptionally uncommon for two different thyroid malignancies to co-exist within the same thyroid gland. Herein, we present two cases where two different thyroid malignancies present as collision tumours of the thyroid gland. The hypothesis, epidemiology and management are discussed here. Case presentation: Case 1 was a 60 year-old woman presented with an accidental finding of left neck swelling. Ultrasound neck identified multinodular goitre with a suspicious left thyroid nodule. Ultrasound-guided fine-needle aspiration cytology of left thyroid nodule confirms papillary thyroid carcinoma. She underwent total thyroidectomy with central compartment neck dissection. However, histopathology reports a presence of medullary thyroid carcinoma and papillary microcarcinoma in the left thyroid gland. Case 2 was a 59 years old woman presented with left vocal cord paralysis with rapidly enlarging of a long-standing left thyroid swelling. Computed tomography identified bilateral thyroid swelling with left mass causing compression to the trachea and oesophagus. The patient subsequently underwent a total thyroidectomy bilateral central and left selective neck node dissections and left primary non-selective nerve re-innervation. A collision tumour with components of both Hurthle cell carcinoma and papillary microcarcinoma has been shown in histopathology. Collision tumours of the thyroid pose a diagnostic as well as a therapeutic challenge. They should be treated in a multidisciplinary team environment, and the care should be unique to the patient. The treatment should usually be directed by the most aggressive neoplasm.
Bangladesh Med J. 2023 Jan; 52(1): 30-34
Tự chủ tài chính tại các vườn quốc gia trực thuộc bộ nông nghiệp và phát triển nông thôn: Thực trạng và giải pháp
Authors: Bùi Thị Minh Nguyệt , Đào Lan Phương , Nguyễn Thị Hồng Thanh
Published: June 2024

Tự chủ tài chính đơn vị sự nghiệp công lập trong đó có vườn quốc gia là một chủ trương lớn của nhà nước góp phần nâng cao hiệu quả sử dụng vốn ngân sách nhà nước và nâng cao thu nhập của người lao động. Bằng phương pháp nghiên cứu định tính, sử dụng dữ liệu có liên quan của 6 vườn quốc gia trực thuộc Bộ Nông nghiệp & Phát triển Nông thôn (2018-2022) cho thấy các vườn quốc gia bước đầu đã chủ động huy động vốn ngoài ngân sách nhà nước. Tuy nhiên, với việc quản lý những tài sản công đặc thù như rừng, đất rừng và hệ sinh thái, các vườn quốc gia đang gặp nhiều rào cản trong việc xây dựng cơ chế tự chủ tài chính. Nguồn tài chính ngoài ngân sách nhà nước chưa ổn định dẫn đến phần lớn các vườn quốc gia chưa tự chủ chi thường xuyên, công tác bảo vệ và phát triển rừng, bảo tồn đa dạng sinh học và đời sống của người lao động còn nhiều khó khăn. Kết quả nghiên cứu là cơ sở khuyến nghị cơ quan quản lý nhà nước ban hành cơ chế đặc thù và cần có lộ trình phù hợp với tiến trình tự chủ tài chính tại các vườn quốc gia.
PENGEMBANGAN PENUNTUN PRAKTIKUM BERBASIS LINGKUNGAN PADA MATERI REAKSI EKSOTERM DAN ENDOTERM UNTUK KELAS XI MIPA SMAN 8 BENGKULU UTARA
Authors: Apriliana Laila Dwi , I Nyoman Candra  , Wiwit Wiwit
Published: June 2024

[The development of environmental based-labwork instruction book on the topic of exotherm and endotherm reaction for student of Class XI of Science, SMAN 8 Bengkulu Utara]The type of this research is a Research and Development study developing an environmental based - labwork instruction book on exothermic and endothermic reaction topic with the aim of knowing the feasibility and response of students to the labwork instruction book and to determine the psychomotor (skills) score ​​of students using it. This research uses the ADDIE development model (Analysis, Design, Development and Evaluation). This research was conducted at SMAN 8 Bengkulu Utara with research subjects namely 9 students in class XI MIPA 3 for small-scale trials and 28 students in class XI MIPA 1 for large-scale trials. Based on the research results, it is found that (1) The developed environment-based labwork instruction book was suitable to be applied with the percentage of material and media validity respectively were 92.5% and 93.3% with very valid criteria (2) Student responses to the labwork instruction guidebook fell in the very good criteria from the aspects of content quality, language and usefulness with an average percentage was 92.2% on a small scale and 92.7% on a large scale. (3) The psychomotor assessment of students using the labwork instruction book fell in a good criteria, 71.0% for the assessment aspect of the preparation stage; 74.8% for assessment of the implementation stage and 84.7% for assessment of the final stage, with an average percentage of 76.8%.
PENGEMBANGAN MODUL ELEKTRONIK BERBASIS KETERAMPILAN BERPIKIR KREATIF MENGGUNAKAN 3D PAGE FLIP PROFESSIONAL PADA MATERI HIDROKARBON
Authors: Fitria Rani , Nurhamidah  , Handayani Dewi
Published: June 2024

Penelitian ini merupakan penelitian pengembangan yang bertujuan untuk mengetahui tingkat kelayakan, respon siswa, tingkat pemahaman siswa terhadap modul elektronik berbasis keterampilan berpikir kreatif menggunakan 3D Page Flip Professional pada materi Hidrokarbon di SMAIT IQRA’ Kota Bengkulu. Penelitian dilakukan pada bulan Agustus-Oktober tahun 2020 di SMAIT IQRA’Kota Bengkulu pada tahun ajaran 2020/2021. Populasi penelitian ini adalah seluruh siswa kelas XI IPA yang berjumlah 120 siswa. Sampel dalam penelitian ini adalah kelas XI IPA 2 di SMA IT IQRA’ Kota Bengkulu. Jenis penelitian ini adalah R&D (Research and Development) yang menggunakan 3 dari 4 tahapan model pengembangan 4D (Four D) diantaranya yaitu Define (Pendefinisian),Design (Perancangan) dan Development (Pengembangan). Data penelitian diperoleh dari angket validasi ahli materi dan media, hasil uji coba skala kecil, hasil uji coba skala besar, angket respon siswa dan tingkat pemahaman siswa terhadap modul elektronik yang dikembangkan. Tingkat kelayakan modul elektronik berdasarkan validasi ahli materi sebesar 93,18% yang menyatakan bahwa kualitas materi pada modul elektronik sudah layak dari aspek materi dan berbasis keterampilan berpikir kreatif, validasi ahli media sebesar 97,20% yang menyatakan bahwa kualitas tampilan pada modul elektronik sudah layak dari aspek media, uji coba skala kecil sebesar 92,47% yang menyatakan bahwa wacana pada modul elektronik mudah dipahami. Respon siswa terhadap modul pada uji pelaksanaan lapangan sebesar 93,92% yang menyatakan bahwa siswa memberikan respon yang sangat baik terhadap modul elektronik yang dikembangkan dan tingkat pemahaman siswa berdasarkan N-Gain Score sebesar 0,37 memiliki kategori sedang. Hal ini menunjukkan bahwa modul elektronik berbasis keterampilan berpikir kreatif menggunakan 3D Page Flip Professional pada materi hidrokarbon sangat layak digunakan sebagai bahan ajar dalam proses pembelajaran
Permainan Squishy Pop Up Sebagai Media Stimulasi Aspek Motorik Halus Anak Usia Dini di TK Lingga Kumara Kelurahan Cempaga Kecamatan Bangli Kabupaten Bangli
Authors: Andari Gusti Ayu Putu Widiasih , Anadhi I Made Gede
Published: June 2024

Squishy pop up adalah permainan yang popular pada dunia anak-anak saat ini.  Popularitas permainan ini dimanfaatkan dengan baik oleh guru yang mengajar di TK Lingga Kumara. Penelitian ini dilakukan dengan tujuan menganalisis protensi penggunaan permainan Squishy pop up terhadap keterampilan motorik halus pada anak usia dini yang berada di TK Lingga Kumara. Penelitian ini menggunakan metode kualitatif dimana hasil penelitian disajikan melalui pendekatan deskriptif. Sumber data primer adalah guru dan anak usia dini di TK Lingga Kumara. Teknik pengumpulan data dilakukan dengan observasi langsung, wawancara dan studi dokumentasi. Analisis data dilakukan dengan menggunakan teori perkembangan motorik anak Thelen dan Whiteneyerr serta menggunakan triangulasi data Model Miles dan Huberman. Hasil penelitian menunjukkan bahwa permainan Squishy pop up memiliki dampak baik diantaranya; meningkatkan koordinasi tangan dan mata, merangsang indera peraba, meningkatkan keterampilan pengendalian gerakan dan meningkatkan konsentrasi. Dengan demikian, permainan Squishy pop up dapat digunakan dengan baik sebagai salah satu alternatif APE dalam stimulasi Pendidikan anak usia dini. Selain memberi banyak dampak positif bahan yang digunakan merupakan bahan yang aman bagi kesehatan anak-anak.
Peran lembaga Pusat Pelayanan Terpadu Pemberdayaan Perempuan dan Anak (P2TP2A) terhadap Kasus kekerasan Anak Usia Dini
Authors: Putri Mutia Syawalistiani , Maryani Kristiana , Fatimah Atin
Published: June 2024

Anak usia dini sejatinya memiliki hak pada saat masih didalam kandungan. Persepsi serta pemahaman masyarakat terkait hak anak usia dini yang masih minim menyebabkan masyarakat itu sendiri kurang memperhatikan keadaan anak usia dini. Melindungi anak-anak dari lingkungan yang berdampak negative yang dapat merugikan anak dari setiap aspek perkembangannya. Pentingnya menjaga kesehatan mental anak usia dini demi pembentukan karakter anak yang baik. Maraknya kasus kekerasan anak usia dini yang menjadi sorotan pemerintah. Pemerintah membuat komitmen untuk menghadirkan sebuah lembaga pemberdayaan perempuan dan anak usia dini yang disebut lembaga Pusat Pelayanan Terpadu Pemberdayaan Perempuan Dan Anak (P2TP2A). Lembaga Pusat Pelayanan Terpadu Pemberdayaan Perempuan Dan Anak (P2TP2A) merupakan sebuah layanan yang terbentuk dilator belakangi terkait perlindungan terhadap perempuan dan anak usia dini. Lembaga P2TP2A ini memberikan beberapa layanan untuk menangani kasus kekerasan yang terjadi seperti trauma terhadap anak dan perempuan dengan memberikan konseling dan rehabilitas.
Partisipasi Peserta Didik pada Program Adiwiyata Melalui Kegiatan Pengelolaan Sampah di Sekolah
Authors: Ardianti Yessy Retno , Amizera Susy , Susanti Rahmi
Published: June 2024

This research aims to determine the form of implementation of participation and the level of student participation in waste management at school. The method used in this research is descriptive qualitative research which aims to describe and analyze student participation in waste management through the Adiwiyata program which has been implemented in schools. The results of research on the implementation of student participation in managing types of waste at Adiwiyata High School in Palembang City include the use of trash bins based on type, and waste management participation activities by students. The use of trash cans by students has been implemented, but there are still students who have not thrown rubbish into trash cans based on the type. Student participation activities in waste management based on type include composting, clean Fridays, collecting, sorting and recycling waste, as well as a healthy canteen. The level of student participation in organic waste management has a percentage of 64.8% in the active category, inorganic waste management has a percentage of 71.3% in the active category, and B3 waste management has a percentage of 56.3% in the quite active category at Adiwiyata High School in Palembang City.
Digitization of Learning Through Virtual Laboratory in Assessing Students' Science Process Skills on Mechanical Wave Material
Authors: Prihatiningtyas Suci , Haryono Heny Ekawati , Putra Ino Angga
Published: June 2024

This study explores the impact of utilizing the PhET virtual laboratory on the development of science process skills among students. Conducted with a repeated treatment design (one group pretest-posttest design), the research involved 30 eleventh-grade science students from MA Bahrul Ulum Jombang. Throughout the study, students engaged with mechanical wave topics using the PhET virtual simulations. Their science process skills were meticulously evaluated through various scientific approaches including problem formulation, hypothesis development, identification of variables, data interpretation, and the ability to draw logical conclusions. The results revealed a marked improvement in these skills following the intervention with the virtual laboratory. Specifically, students demonstrated enhanced abilities in forming coherent hypotheses, accurately identifying relevant variables, and effectively interpreting complex data sets. Moreover, their skills in synthesizing information to formulate valid conclusions were significantly bolstered. The use of the PhET virtual laboratory not only fostered a deeper understanding of mechanical wave concepts but also facilitated a more interactive and engaging learning environment. These findings advocate for the broader integration of such technological tools in science education, emphasizing their role in enriching students' learning experiences and advancing their analytical and scientific thinking skills.
Utilization of Technology in Physics Education: A Literature Review and Implications for the Future Physics Learning
Authors: Faresta Rangga Alif , Nicholas Teo Zhao Ser Bryan , Chi Yixuan , Sinambela Indah Astri Natalia , Mopoliu Abdul Ziqron
Published: June 2024

The integration of technology in physics education is transforming teaching methods and learning experiences, offering a dynamic approach to understanding complex concepts that traditional methods struggle to convey effectively. This literature review critically examines the current trends in the utilization of technological tools such as simulations, virtual and augmented realities, and interactive software within physics education. Employing the PRISMA framework, the study analyzed a comprehensive dataset from the SCOPUS database, focusing on publications up to May 1, 2024. The results highlight the substantial benefits of technology in enhancing student engagement and understanding of physics, along with identifying the challenges such as inadequate teacher training and unequal access to technology. The review emphasizes the need for professional development programs and equitable technology distribution to maximize the educational benefits. These findings advocate for an evolved educational model that integrates these technological advances to better prepare students for a future dominated by technology, ensuring that physics education remains both current and effective.
MİLLÎ MÜCADELE SÜRECİNDE İSVİÇRE BASININDA MUSTAFA KEMAL PAŞA
Authors: Öz Enes
Published: June 2024

Uluslararası basın kuruluşları, Millî Mücadele esnasında Küçük Asya olarak tabir ettikleri Türkiye’deki gelişmeleri yakından takip etmişlerdir. İsviçre basını da bu noktada gözünü Türkiye’ye çevirmiş, Millî Mücadele haberlerine ve bu haberlerin içeriğinde de Mustafa Kemal Paşa ile ilgili gelişmelere yer vermiştir. Bu bağlamda İsviçre basınına bu süreçte yansıyan Mustafa Kemal Paşa içerikli haberlerin aktarılması, çalışmanın esas argümanını oluşturmuştur. Böylece, İsviçre basınından hareket edilerek Avrupa kamuoyunda Mustafa Kemal Paşa haberlerinin araştırılması yapılmıştır. Bu noktada Millî Mücadele döneminde İsviçre basınında Mustafa Kemal Paşa hakkındaki haberlerin hangi gelişmelerle birlikte yansıdığı ve haberler aktarılırken kullanılan ifadelerin ne yönde olduğunun tespiti yapılmak istenmiştir. Zira tarafsız olarak kabul görmüş bir ülkede kamuoyunun Millî Mücadele esnasında, bu hareketin liderini nasıl haberleştirdiği bir soru olarak sorulabilmektedir. Çalışmada, İsviçre basınında bulunan ve kamuoyunun nabzının tam anlamıyla tutulabileceği ulusal gazetelerden yararlanılmıştır. Mustafa Kemal Paşa’nın yer aldığı haberler ayıklanarak tahlil edilmiş ve çalışmada kullanılmıştır. Bu kapsamda 1919-1922 tarihleri yani Mustafa Kemal Paşa’nın Samsun’a çıkışından, Lozan Konferansı sürecinin başlamasından hemen önceki döneme kadar olacak şekilde konu daraltılmıştır. Böylece, Mustafa Kemal Paşa özelindeki mevcut literatüre katkı sağlanması hedeflenmiştir. 1919 yılından itibaren, Mustafa Kemal Paşa’nın geçtiği içerikler İsviçre basınında yoğunlaşmaya başlamıştır. İlk olarak onun Anadolu’daki teşkilatlanmanın lideri olması haberleri tespit edilmiştir. Daha sonraki dönemde ise Millî Mücadele’de yürütülen savaşlar döneminde gelişmeler hakkında bilgiler paylaşılırken, Mustafa Kemal Paşa’ya haber ayrıntılarında yer verilmiştir. Mustafa Kemal Paşa’nın aldığı kararlar ve verdiği talimatları içeren haberler bu dönemde ağırlık kazanmıştır. Büyük Taarruz sürecinde ise bundan sonra Mustafa Kemal Paşa’nın vereceği kararların dikkatle takip edildiğini gösterir nitelikte haberler İsviçre basınına yansımıştır.
Treatment of Dermatitis Artefacta: A Systematic Review
Authors: Estill Mariah C. , Jafferany Mohammad
Published: June 2024

Dermatitis artefacta (DA) is a rare psychocutaneous disorder characterised by self-inflicted skin lesions that the patient denies producing. DA poses a complex clinical challenge to clinicians as patients often are resistant to the diagnosis, and can be hesitant to follow up with psychiatric or psychological services. There is a need to understand the optimal approach for management of patients with DA. This systematic review was undertaken to address this gap in knowledge.

A search was conducted on PubMed and Embase using the following search strategy: Dermatitis artefacta OR factitious dermatitis OR factitial dermatitis OR artefactual skin AND treatment OR management OR therapy OR psychotherapy OR pharmacotherapy. Included studies were published from inception to 5ᵗʰ April 2023 in peer-reviewed journals, and discussed the treatment and management of DA. Studies were excluded if they were published in a language other than English.

A total of 11 retrospective or prospective studies were included in this systematic review. They all found DA to be challenging to treat, with every study reporting patients experiencing a comorbid psychiatric condition or associated psychosocial stressor. Overall, there were better reported outcomes among follow-up patients treated in psychodermatology clinics with multidisciplinary teams of dermatologists, psychiatrists, and psychologists.

Medical treatments can help with symptom control and promote wound healing, while psychological and psychiatric treatments can help address underlying psychosocial stressors for the condition. Further research is needed to evaluate optimal management and long-term treatment outcomes in patients with DA.
The Influence of Marketing Communication and Service Quality on Customer Decisions at BJB Syariah KCP Sumber Cirebon
Authors: Alvien Septian Haerisma  , Abdul Ghoni  , Dian Lestari
Published: June 2024

Various studies have explored the impact of marketing communications and service quality on customer decisions. In carrying out its operational activities, Sharia banking has several factors that can influence the public to decide to use the products and services offered, these two factors include marketing communications and service quality. Therefore, this research aims to determine the influence of marketing communications and service quality on customers' decisions to use Wadiah IB Maslahah savings. The type of research used is survey research using a quantitative approach. The number of samples in this research was 70 samples. By using the Slovin formula, the standard error used is 0.1 or 10%. The data analysis techniques used are validity tests, reliability tests, classical assumption tests, multiple linear regression tests, multiple coefficient tests, and hypothesis tests in the form of t-tests (partial) and F-tests (simultaneous), where all testing processes use IBM SPSS. The results of this research show that there is a partial positive and significant influence between marketing communication variables on customer decisions. Then there is a significant influence between service quality variables on customer decisions. And simultaneously marketing communication variables and service quality influence customer decision variables.
Comparative study of a novel proximal femoral bionic nail and three conventional cephalomedullary nails for reverse obliquity intertrochanteric fractures: a finite element analysis
Authors: Yang Yanjiang , Tong Yu , Cheng Xiaodong , Zhu Yanbin , Chen Wei , Cui Yunwei , Zhang Qi , Zhang Yingze
Published: June 2024

Purpose

Conventional cephalomedullary nails (CMNs) are commonly employed for internal fixation in the treatment of reverse obliquity intertrochanteric (ROI) fractures. However, the limited effectiveness of conventional CMNs in addressing ROI fractures results in significant implant-related complications. To address challenges associated with internal fixation, a novel Proximal Femoral Bionic Nail (PFBN) has been developed.

Methods

In this study, a finite element model was constructed using a normal femoral specimen, and biomechanical verification was conducted using the GOM non-contact optical strain measurement system. Four intramedullary fixation approaches—PFBN, Proximal Femoral Nail Antirotation InterTan nail (ITN), and Gamma nail (Gamma nail)—were employed to address three variations of ROI fractures (AO/OTA 31-A3). The biomechanical stability of the implant models was evaluated through the calculation of the von Mises stress contact pressure and displacement.

Results

Compared to conventional CMNs, the PFBN group demonstrated a 9.36%–59.32% reduction in the maximum VMS at the implant. The A3.3 ROI fracture (75% bone density) was the most unstable type of fracture. In comparison to conventional CMNs, PFBN demonstrated more stable data, including VMS values (implant: 506.33 MPa, proximal fracture fragment: 34.41 MPa), contact pressure (13.28 MPa), and displacement (17.59 mm).

Conclusion

Compared to the PFNA, ITN, and GN, the PFBN exhibits improvements in stress concentration, stress conduction, and overall model stability in ROI fractures. The double triangle structure aligns better with the tissue structure and biomechanical properties of the proximal femur. Consequently, the PFBN has significant potential as a new fixation strategy for the clinical treatment of ROI fractures.
Hybrid films loaded with 5-fluorouracil and Reglan for synergistic treatment of colon cancer via asynchronous dual-drug delivery
Authors: Mao Hairong , Zhou Jianfeng , Yan Liang , Zhang Shuping , Yu Deng-Guang
Published: June 2024

Combination therapy with oral administration of several active ingredients is a popular clinical treatment for cancer. However, the traditional method has poor convenience, less safety, and low efficiency for patients. The combination of traditional pharmaceutical techniques and advanced material conversion methods can provide new solutions to this issue. In this research, a new kind of hybrid film was created via coaxial electrospraying, followed by a casting process. The films were composed of Reglan and 5-fluorouracil (5-FU)-loaded cellulose acetate (CA) core-shell particles in a polyvinylpyrrolidone (PVP) film matrix. Microscopic observations of these films demonstrated a solid cross section loaded with core-shell particles. X-ray diffraction and Fourier-transform infrared tests verified that the Reglan and 5-FU loaded in the films showed amorphous states and fine compatibilities with the polymeric matrices, i.e., PVP and CA, respectively. In vitro dissolution tests indicated that the films were able to provide the desired asynchronous dual-drug delivery, fast release of Reglan, and sustained release of 5-FU. The controlled release mechanisms were shown to be an erosion mechanism for Reglan and a typical Fickian diffusion mechanism for 5-FU. The protocols reported herein pioneer a new approach for fabricating biomaterials loaded with multiple drugs, each with its own controlled release behavior, for synergistic cancer treatment.
Distribution and dynamic changes of Huanglongbing pathogen in its insect vector Diaphorina citri
Authors: Guo Chang-Fei , Kong Wei-Zhen , Mukangango Marguerite , Hu Yu-Wei , Liu Yu-Tao , Sang Wen , Qiu Bao-Li
Published: June 2024

The Asian citrus psyllid (ACP) Diaphorina citri Kuwayama is the leading vector of Candidatus Liberibacter asiaticus (CLas), the causative agent of citrus Huanglongbing (HLB) disease. The distribution and dynamics of CLas within ACP are critical to understanding how the transmission, spread and infection of CLas occurs within its host vector in nature. In this study, the distribution and titer changes of CLas in various tissues of ACP 5th instar nymphs and adults were examined by fluorescence in situ hybridization (FISH) and real-time quantitative PCR (qPCR) techniques. Results demonstrated that 100% of ACP 5th instar nymphs and adults were infected with CLas following feeding on infected plants, and that CLas had widespread distribution in most of the tissues of ACP. The titers of CLas within the midgut, salivary glands and hemolymph tissues were the highest in both 5th instar nymphs and adults. When compared with adults, the titers of CLas in these three tissues of 5th instar nymphs were significantly higher, while in the mycetome, ovary and testes they were significantly lower than those of adults. FISH visualization further confirmed these findings. Dynamic analysis of CLas demonstrated that it was present across all the developmental ages of ACP adults. There was a discernible upward trend in the presence of CLas with advancing age in most tissues of ACP adults, including the midgut, hemolymph, salivary glands, foot, head, cuticula and muscle. Our findings have significant implications for the comprehensive understanding of the transmission, dissemination and infestation of CLas, which is of much importance for developing novel strategies to halt the spread of CLas, and therefore contribute to the efficient prevention and control of HLB.
Research on the transport behavior of microparticle proppants inside natural fractures
Authors: Liu Huifeng , Wang Xiaohan , Xu Ning , Chen Zhangxin , Peng Yan
Published: June 2024

As a crucial exploration technique for unconventional reservoirs, hydraulic fracturing enables the formation of complex fracture networks, thereby facilitating the flow of oil and gas. The closure of natural fractures decreases stimulation performance. Microparticle proppants are used to fill natural fractures and effectively increase the stimulation area. The 100-mesh proppant conventionally used in field operations may be insufficiently small to effectively access natural fractures. In order to effectively overcome natural fractures closure, microparticle proppants (i.e., proppants with a diameter of 75 μm (200-mesh) or less) are required. The particle size threshold test of microparticle proppants placement is conducted to determine the size threshold of proppants flowing into natural fractures. The microparticle proppants placement experiment in multi-branch fractures is conducted to investigate the volume difference of proppants in different fractures. Numerical simulations are performed to model proppant transport within fractures of actual dimensions to facilitating the optimization of stimulation parameters. The main conclusions are as follows: (1) Effective inflow of microparticle proppants requires a size threshold of proppants. For the 200-mesh proppants, the size should be less than half of natural fractures width when microparticle proppants effectively flow into natural fractures. (2) Sand concentration affects the size threshold of microparticle proppants. The size threshold should appropriately increase to ensure the inflow of proppant. (3) Difference of multi-branch fracture width has a significant effect on volume of microparticle proppants inside fractures. When the width ratio of multi-branch fractures exceeds 2, this effect becomes obvious. (4) Particle size has an effect on proppant placement. 200-mesh proppants can obtain uniform distribution of proppants among natural fractures. 140-mesh proppants can obtain maximum proppant volume among natural fractures. Sand concentration significantly affects proppant placement performance. The optimal sand concentration is 60kg/m3. The pumping rate for a single cluster fracture should not be excessively low. The pumping rate should be larger than 0.5m3/min and the optimal pumping rate 2m3/min. In this paper, the particle size and concentration of particulate proppant are optimized and the geometric characteristics of fractures are considered. These conclusions provide important practical guidance and scientific basis for the optimization and application of hydraulic fracturing technology.
A study of factors and their influence on mathematics-related beliefs and performance in Turkey
Authors: Kandemir Mehmet Ali , Eryilmaz Nurullah , Shelley Mack
Published: June 2024

The present study endeavors to uncover the intricate nexus among pertinent variables, including self-efficacy, perceived usefulness, parental education levels, and gender, and their relationship with mathematics performance. To achieve this objective, several hypotheses were tested, and a path model was estimated. The study cohort comprised 117 8th-grade students (64 females, 53 males) enrolled in a secondary school in Turkey. Results, in general, supported research hypotheses and the path model. Males' mathematics self-efficacy was found to be higher than females. No significant gender difference was found in the mathematics performance score in the initial analysis. Nevertheless, gender made a significant contribution to the prediction of mathematics performance beyond the effects of other variables in the hierarchical regression analysis. Consistent with theoretical predictions, females' mathematics self-efficacy expectations were unrealistically low compared to males. However, the effect of self-efficacy on performance was found to be invariant across gender. Perceived usefulness was found to be moderately correlated with performance but made little contribution to the prediction of performance above and beyond the effects of other variables.
The indicative effects of apolipoproteins on organic erectile dysfunction: bridging Mendelian randomization and case-control study
Authors: Zhang Zhexin , Yan Mo , Li Yuezheng , Pan Yang , Wang Shangren , Xu Mingming , Zhou Hang , Liu Xiaoqiang
Published: June 2024

The existing research on the association between apolipoproteins (Apos) and erectile dysfunction (ED) primarily relies on observational studies and does not distinguish between organic and psychogenic causes when diagnosing ED. It is difficult to believe that Apos play a role in psychogenic ED. To address these issues, our study explored the causal relationship between lipoproteins and ED using Mendelian randomization (MR) analysis and differentiate between organic and psychogenic ED through the use of nocturnal penile tumescence and rigidity (NPTR) monitoring. Multivariate MR analysis revealed significant causal associations between high-density lipoprotein (HDL), Apo A1, and Apo B/A1 with ED (OR and 95% CI were 0.33 (0.14-0.78), 3.58 (1.52-8.43), and 0.30 (0.13-0.66)). we conducted statistical and analytical analyses on the data of 212 patients using multivariate analyses and receiver operating characteristic (ROC) curves. Patients with organic ED had significantly lower levels of HDL, Apo A1 and Apo A1/B, whereas patients with organic ED had considerably higher levels of Apo B and low-density lipoprotein (LDL). The diagnostic value of Apos in predicting the risk of organic ED was evaluated using ROC curves. The results indicated that Apo A1 and Apo A1/B demonstrated good predictive value. HDL, Apo A1, and Apo A1/B have been identified as risk factors for ED in our study. Furthermore, our research highlights the significance of Apo A1 and Apo A1/Apo B in the development of organic ED and suggests their potential use as indicators to assess the risks associated with organic ED.
The threshold effect of triglyceride glucose index on diabetic kidney disease risk in patients with type 2 diabetes: unveiling a non-linear association
Authors: Wang Huabin , Chen Guangming , Sun Dongmei , Ma Yongjun
Published: June 2024

Background

Previous studies have confirmed that the triglyceride glucose (TyG) index, recognized as a reliable marker of insulin resistance, is an important risk factor for diabetic kidney disease (DKD). However, it is still unclear whether the DKD risk continues to increase linearly with the elevation of TyG index. This study aimed to thoroughly investigated the intrinsic relationship between TyG index and DKD risk in type 2 diabetes (T2D).

Methods

This cross-sectional study included 933 patients with T2D in China, who were categorized into DKD and non-DKD groups and stratified by TyG index levels. Logistic regression analysis identified the independent risk factors for DKD. The association between DKD risk and TyG index was evaluated using the restricted cubic spline (RCS) curves analysis. The R package ‘CatPredi’ was utilized to determine the optimal cut-off point for the relationship between DKD risk and TyG index, followed by threshold effect analysis.

Results

The prevalence of DKD was 33.01%. After adjusting for confounding factors, TyG index was identified as a prominent clinical risk factor for DKD, showing the highest odds ratio (OR 1.57 (1.26 - 1.94), P<0.001). RCS analysis revealed a non-linear relationship with a threshold interval effect between the TyG index and DKD risk. When TyG index ≤ 9.35, DKD risk plateaued at a low level; however, when TyG index > 9.35, DKD risk increased gradually with rising TyG index. Among patients with TyG index > 9.35, each 1-unit increase was associated with a 1.94-fold increased DKD risk (OR=1.94 (1.10 - 3.43), P=0.022).

Conclusion

The DKD risk presented a threshold effect with the increase of TyG index, initially stable at a low level, and then gradually rising when the TyG index is above 9.35.
A study on the evolutionary game theory of third-party governance of environmental pollution based on the quasi-co-owned relationship of pollution rights
Authors: Hu Zikun , Wang Yina , Liao Wenjun , Tao Tingyu , Zhang Hao
Published: June 2024

The third-party governance of environmental pollution and the pollution rights trading system are two typical examples of modern environmental governance systems. In China, the quasi-co-owned relationship of pollution rights between pollution-discharging and pollution-control enterprises is the link through which to achieve synergy between the two factors. To explore how to achieve such synergy, first, the “principle of no-fault liability” is introduced, and the responsibilities of pollution-discharging enterprises and pollution-control enterprises are defined. Second, based on the quasi-co-owned relationship of pollution rights, a revenue-sharing mechanism for pollution rights trading is designed. Finally, a tripartite evolutionary game model consisting of pollution-discharging enterprises, pollution-control enterprises and local governments is constructed, and numerical simulation is performed. The results are as follows. 1) By setting a reasonable market trading price for pollution rights, a reward and punishment distribution coefficient, an improvement in reputation gains, and a saving in pollution rights indicators become conducive to the formation of cooperative relationships between pollution-discharging and pollution-control enterprises, for which the reasonable range of the reward and punishment distribution coefficient is (0.3, 0.4]. 2) Regardless of whether a government subsidy is provided, the optimal range of the revenue-sharing coefficient from pollution rights trading is [0.5, 0.6]. 3) When a government subsidy is withdrawn, increasing the market trading price and surplus indicators of pollution rights can promote the stable operation of the third-party governance model. 4) An increase in policy support and administrative accountability of higher levels of government and a reduction in supervision costs for local governments can help these parties effectively avoid addressing the absence of local government supervision. It is recommended that third-party governance enterprises participate in pollution rights trading to implement the main responsibilities of pollution-discharging and pollution-control enterprises and to set a reasonable revenue-sharing coefficient and reward and punishment distribution coefficient of pollution rights.
Do professionalism, leadership, and resilience combine for professional identity formation? Evidence from confirmatory factor analysis
Authors: Ryan Aine , Moran Catherine N. , Byrne David , Hickey Anne , Boland Fiona , Harkin Denis W. , Guraya Shaista S. , Bensaaud Abdelsalam , Doyle Frank
Published: June 2024

Introduction

Professional identity formation (PIF) is an ongoing, self-reflective process involving habits of thinking, feeling and acting like a physician and is an integral component of medical education. While qualitative work has suggested that PIF is informed by professionalism, resilience, and leadership, there is a dearth of quantitative work in this area. Multiple methods build rigor and the present study aimed to quantitatively assess the relative psychometric contributions of professionalism, resilience, and leadership constructs to informing PIF, using a latent factor analysis approach.

Methods

We analyzed data from the PILLAR study, which is an online cross-sectional assessment of a pre-clinical cohort of medical students in the RCSI University of Medicine and Health Sciences, Dublin, using established and validated quantitative measures in each area of interest: PIF, professionalism, leadership and resilience. A total of 76 items, combining four validated scales, along with a selection of demographic questions, were used. The hypothesis that PIF is informed by, and correlates with, professionalism, resilience and leadership was examined by conducting a confirmatory factor analysis of a proposed three-factor higher-order model. Model estimation used Maximum Likelihood Method (MLM) with geomin rotation. The hypothesized (measurement) model was examined against an alternative (saturated) model, as well as a three-factor model.

Results

Latent variable analysis from 1,311 students demonstrated that a three-factor higher-order model best fit the data; suggesting PIF is informed by professionalism, resilience, and leadership, and that these constructs are statistically distinct and account for differential aspects of PIF. This higher-order model of PIF outperformed both the saturated model and the three-factor model. The analysis of which component may be the most or least influential was inconclusive, and the overall model was not influenced by year of training.

Discussion

Building upon existing conceptual contentions, our study is the first to quantitatively support the contribution of professionalism, resilience, and leadership to the development of professional identity, and to delineate the inter-relationships between PIF and these constructs. This information can be used by medical educators when designing curricula and educational strategies intended to enhance PIF. Future work should seek to assess the influence of these constructs longitudinally.