bluuebunny/crossref_metadata_2025 huggingface dataset:
PERANCANGAN MOTION GRAPHIC PENGENALAN AUTOMATED UVC TROLLEY DI BALAI INFORMASI TEKNOLOGI LIPI BANDUNG
Authors: Arya Arya Sindhora , Saputra Deni , Tisnawati Rini
Published: December 2022

Penelitian ini bertujuan untuk memperkenalkan Automated UVC Trolley (AUT) sebagai alat disinfekstan yang bisa dikembangkan dengan baik. Penelitian ini mengkaji media yang dikembangkan oleh UPT BPI LIPI untuk memperkenalkan alat tersebut.

Yang mana pada penggunaan bidang promosi dengan menerapkan Multimedia khususnya Motion Graphic memiliki dampak yang sangat baik pada masyarakat salah satunya sebagai  pengenalan Company Profile. Dalam penelitian ini peneliti menggunakan 3 software dari Adobe  Corporation. yaitu Adobe Premiere Pro, Adobe Illustrator dan Adobe After Effect. Oleh karena itu peneliti menerapkan Motion Graphic sebagai media promosi berupa produk ataupun jasa karena dinilai paling efisien dalam bidang informasi dan teknologi.
PERANCANGAN SISTEM EKSTRAKURIKULER PADA SMP NU AL MA’RUF KUDUS BERBASIS WEB DAN SMS GATEWAY
Authors: Devy Octaviana Adhita Arif Setyawan
Published: December 2022

Analisa dan Perancangan Sistem Ekstrakurikuler Pada SMP NU Al Ma’ruf Kudus Berbasis Web ini membahas mengenai sistem pendataan siswa ekstrakurikuler, absensi ekstrakurikuler, penilaian ekstrakurikuler dan laporan ekstrakurikuler. Dimana admin akan menginputkan data siswa sesuai NIS yang dimiliki, sehingga siswa dapat melakukan pendaftaran ekstrakurikuler dan koordinator Pembina dapat melakukan penilaian dan menghasilkan laporan yang diterima oleh kepala sekolah. Sistem ini juga menyediakan SMS Gateway untuk informasi melalui seluler. Dengan sistem ini koordinator pembina dapat  mendata  penilaian ekstrakurikuler  dan  menghasilkan  output  laporan ekstrakurikuler yang dapat dicetak.

Hasil akhir perancangan tersebut menghasilkan Aplikasi Sistem Ekstrakurikuler Pada SMP NU Al Ma’ruf Kudus Berbasis Web dan SMS Gateway.
SISTEM PENUNJANG KEPUTUSAN RENTAL MOBIL DENGAN MENGGUNAKAN METODE FUZZY
Authors: Zulkarnaen Rifaldi , Gustian Dudih
Published: December 2022

Rental mobil adalah usaha yang bergerak di bidang jasa rental mobil. Setiap tahun pasar sewa mobil laris banyak diburu oleh konsumen khususnya di barat dan di hari libur dan pastinya harga sewa mobil yang tentunya bermacam-macam sesuai dengan harga sewa jarak atau hari yang berbeda beda. Namun seringkali kesulitan dalam bidang pengelolaan pembukuan atau pendataan antrian konsumen dengan sistem manual, baik di bidang pemesanan maupun data pembukuan yang dibutuhkan. Maka penulis melakukan penelitian dengan menggunakan metode logika fuzzy dimana metode tersebut sangat membantu dalam mengambil keputusan pada saat konsumen membutuhkan kendaraan dan sangat membantu pihak manajemen perusahaan. Metode ini akurat dengan akurasi 90%, metode ini menggunakan metode mamdani yaitu menggunakan operasi min-max atau max-product. Untuk mendapatkan output, diharapkan penelitian ini dapat memberikan solusi dalam mengatur data pemesanan, waktu keberangkatan dan pemilihan kendaraan pada interior mobil sehingga pengelolaan data dapat lebih optimal.
PERANCANGAN SISTEM PENGGAJIAN KARYAWAN BERBASIS WEB PADA PT. TUNAS UTAMA KOMPUTER BANDUNG
Authors: Surahman Roni
Published: December 2022

Penelitian ini bertujuan untuk memberikan suatu solusi dengan merancang dan mengaplikasikan suatu alur kerja sistem absensi karyawan berdasarkan sistem absensi dan penggajian manual yang sudah ada pada PT. Tunas Utama Komputer Bandung yang masih kurang efektif dan efisien, dan aplikasi absensi yang terkomputerisasi dengan baik antara sistem basis data, user interface, dan user itu sendiri.

Metode penelitian yang digunakan adalah metode deskriptif yaitu metode yang hanya menggambarkan dan meringkaskan berbagai kondisi, situasi atau berbagai variable. Pengembangan atau pendekatan sistem informasi yang digunakan dalam Tugas Akhir ini menggunakan metode pengembangan Waterfall. Sedangkan alat-alat yang digunakan dalam analisa perancangan sistem adalah Flowmap, Diagram konteks, Data Flow Diagram & UML, sedangkan implementasi dari perancangan sistem adalah bahasa pemograman PHP dan MySQL Server sebagai database. Pembuatan sistem informasi penggajian karyawan ini di integrasikan dengan sistem absensi karyawan yang dapat membantu kinerja PT Tunas Utama Komputer tertama dalam bidang manajemen SDM dan manajemen keuangan agar lebih teratur, terkomputerisasi dan berbasis Web.

Hasil Penelitian sistem penggajian karyawan yang terintegrasi  dengan sistem absensi berbasis web dapat mengatasi permasalahan yang sering muncul pada sistem sebelumnya. Misalnya duplikasi data, kerusakan dan kesalahan rekap data, sehingga implementasi sistem penggajian berbasis web dari My.SQL sebagai tempat penyimpanan data atau dokumen sehingga data yang ada tidak akan hilang. Pengelolaan keuangan pun menjadi lebih efektif dan efisien.
Aile Sanat ve Eğitim Merkezi Kursiyelerinde Üreme Sağlığı Konulu Müdahale Çalışması
Authors: Durduran Yasemin , Karabacak Vildan , Yücel Mehtap , Şahin Tahir Kemal
Published: December 2022

ÖZET
Amaç: Bu çalışmada, Aile Sanat ve Eğitim Merkezindeki (ASEM) kursiyerlerin, üreme sağlığı konusundaki
bilgi durumlarını saptamak ve farkındalık oluşturmak, bilgi eksikliklerini tamamlamak amacıyla verilen
eğitimin etkinliğini belirlemek amaçlanmıştır.
Yöntemler: Çalışma, 1 Mayıs-30 Haziran 2018 tarihleri arasında ASEM’de eğitim alan 80 kursiyerle
yapılmıştır. Gönüllü katılımcılara ön test, interaktif eğitim ve ardından son test uygulanmıştır. Verilerin
istatistiksel analizi, SPSS 27,0 paket programı kullanılarak yapılmıştır. Verilerin analizinde, McNemar X2
testi, kullanılmıştır. İstatistiksel anlamlılık için sınır değer olarak p<0,05 kabul edilmiştir.
Bulgular: Çalışmaya, yaş ortalaması 41,33±9,54 yıl olan 80 kursiyer katılmıştır. Ön testte, katılımcıların
%20,0’ı, son testte %53,8’i ulusal kanser tarama programları ile taranan kanserlerin hepsini doğru olarak
bilmiştir. Ayrıca ön testte kadınların %32,5’inin kendi kendine meme muayenesi yapılma zamanını doğru
olarak bildiği görülürken eğitim sonrası son testte bu oranın %85,0’a yükseldiği görülmüştür. Üreme sağlığı
alanında verilen tüm konularda ön test ile son test arasında istatistiksel olarak anlamlı fark bulunmuştur
(p<0,05).
Sonuç: Katılımcıların aile planlaması, cinsel yolla bulaşan enfeksiyonlar ve tarama programında yer alan
kadın kanserlerine ilişkin düşük düzeyde bilgi sahibi oldukları ve verilen eğitim müdahalesinin yararlı
olduğu bulunmuştur. Ancak eğitim müdahalesi ile yeterli düzeyde artış sağlanamadığı belirlenmiştir. Bu da
kadınları hedef alan ve üreme sağlığı alanındaki konuları içeren eğitim programlarının periyodik ve güncel
içeriklerle tekrar edilmesi gerekliliğini göstermektedir.
Anahtar Kelimeler: Eğitim, kadın sağlığı, üreme sağlığı
Timik Tümörlerin Sistemik Tedavisinde Gelişmeler
Authors: Araz Murat
Published: December 2022

ÖZET
Timomalar ve timik karsinomlar genellikle ön mediasten yerleşimli timus kökenli nadir görülen tümörlerdir.
İlk tanı anındaki evre ve timik tümörün cerrahi olarak tam çıkarılabilmesi en önemli prognostik faktörlerdir.
Hastaların evresine göre neoadjuvan/adjuvan kemoterapi ve radyoterapiyi içeren tedavi stratejileri multidisipliner
tümör konseylerinde planlanmalıdır. Ancak, lokal tedavilere rağmen hastaların az bir kısmında zaman içinde
nüks gelişebilmekte veya daha ilk tanı anında metastaz saptanabilmektedir. Lokal tedavilere uygun olmayan
hastalarda platin ve doksorubisin ile kombine kemoterapi rejimleri standart birinci basamak tedavidir. Ancak
ikinci basamakta kesin kabul görmüş bir tedavi önerisi yoktur. Birinci basamak tedavi sonrası progresyon gelişen
hastalarda vasküler endotelyal büyüme faktörünü hedefleyen tirozin kinaz inhibitörleri ve immünoterapiler
ile yapılan çalışmaların sonuçları yakın zamanda açıklanmıştır. Bu derlemede, timoma ve timik karsinomlu
hastaların genel olarak tedavi yönetimini, hedefli tedavilerin ve immünoterapi çalışmalarının sonuçlarını ve
güncel pratiğe potansiyel yansımalarını analiz ettik.
Anahtar Kelimeler: Hedefleyici tedaviler, immünoterapi, timik karsinom, timoma
Perioperative Anaesthetic Management of Pediatric Patients in Craniosynostosis
Authors: Andan İbrahim , Başar İbrahim , Kaydu Ayhan , İpek Yusuf , Arpa Abdurrahman
Published: December 2022

ÖZET
Amaç: Bu çalışmada, hayatı tehdit eden komplikasyonlarla seyredebilen kraniyosinostoz nedeniyle ameliyat
edilen çocuk hastalarda perioperatif anestezi yönetimini sunmayı amaçladık.
Gereçler ve Yöntem: Ocak 2009-Ocak 2021 arasında opere edilen 26 kraniyosinostoz hastasının tamamının
dosyasını geriye dönük olarak inceledik. Hastaların demografik verileri, ASA skorları, anestezi ve ameliyat
süreleri, ek anomali koşulları, hava yolu ve kanama yönetimi ile komplikasyonları analiz edildi.
Bulgular: Çalışmaya alınan 26 hastanın 16'sı trigonosefali, 4'ü skafosefali, 3'ü plajiyosefali ve 3'ü mikst
tipte idi. Hastaların 20'si (%76.9) erkek, 6'sı (%23.1) kadındı. 26 hastanın beşinde (%19.23) ek anomaliler (1
Apert sendromu, 2 kardiyak anomali ve 2 hidrosefali) vardı. Ortalama ameliyat süresi 167.03 dk ve anestezi
süresi 179.92 dk idi. Hastaların direkt laringoskopisinde CL skorları değerlendirildi. Beş hastada (%19.2)
CL I, 13 hastada (%50.0) CL II ve 8 hastada (%30.8) CL III bulundu. Ameliyat sırasında 5 hastada (%19.23)
şiddetli hipotansiyon gözlendi. Bu hastalara eş zamanlı kan ve sıvı infüzyonu ile 0.03 mg/kg/dk dozunda
noradrenalin uygulandı. Ameliyat öncesi ortalama hematokrit değerleri %35.99, ameliyat sırasında %26.85
(0.001) olan hastaların preoperatif ve intraoperatif hematokrit değerleri arasında istatistiksel olarak
anlamlı fark bulundu (p 0,001).
Sonuç: Kraniosinostozlu pediatrik hastaların havayolu yönetiminin zor olduğunu ve intraoperatif masif
kanama riski olduğunu saptadık. Bu hastalarda dikkatle planlanmış anestezi yönetimi gerekir.
Anahtar Kelimeler: Kraniosinostoz, pediatrik hastalar, anestezi yönetimi, kanama yönetimi
Toil and Dream On
Authors: Delos Reyes Carmina
Published: December 2022

The editorship came in as a big, BIG surprise. This with a bang and the news that our dear EIC (over the last 15 years), Dr. Cecilia Maramba-Lazarte will relinquish her post. The whole gamut of human emotions came into play as if I were this character Riley from “Inside Out”(Disney). I felt overly surprised. There was sadness, disgust, even fear. Anger? Angst? There was no perfect word to describe what it felt to be tasked to carry on and bring further “THE PIDSP JOURNAL”.
Fever Of Unknown Origin In Children: A Five-Year Review
Authors: Cabanalan-Rivera Ma. Fema , Gonzales Ma. Liza M. Antoinette
Published: December 2022

Objective: The clinical presentation, outcome, and risk factors for mortality in children with Fever of Unknown Origin (FUO) were determined. Methods: Medical records of pediatric patients admitted for FUO from January 2009 to December 2013 were reviewed. Clinical manifestations, physical exam findings, diagnostic work-ups and final diagnosis were determined, as well as the relationship between final diagnosis and risk for mortality. Results: Fifty-seven patients with FUO were included. Weight loss, cough, colds, and rashes were common symptoms while pallor, lymphadenopathies, and hepatomegaly were common physical exam findings. All patients underwent Phase I evaluation for FUO, while 73.7% underwent further diagnostic tests. A specific etiology was established in 96.5% of cases: infectious, 43.9%, connective tissue disease, 38.6%, and hematologic/oncologic, 14%. Two cases remained to have no specific diagnosis. Majority of patients had a benign course and were discharged improved (84.2%). The mortality rate is 15.8% and was not associated with any disease category (p-value 0.204). Conclusion: FUO in children occurs across all age groups. Its clinical presentations are varied and non-specific and common signs and symptoms are pallor, lymphadenopathies, weight loss, cough, colds. and joints pains. Infection is the most common cause of FUO in children, followed by connective tissue diseases and hematologic and oncologic diseases. The mortality rate from FUO is 15.8%.
Second Stop
Authors: Dy-Co Arlene
Published: December 2022

If the first was fast… the second will be faster… This second issue from your new editors and editorial board is by no means fast but faster than the first one. Without any formal training on medical journal editing, this task is definitely overwhelming if not daunting. A noted medical journal editor once wrote and I quote “I hope that one day every editor gets some training before beginning work.” And we began our work… we have to adapt to you, our reader’s point of view while upholding the author’s voice. More than checking a paper’s spelling and grammar, we prioritize readability instead of merely coming out with a repository of data.
Association of Factors with Successful Treatment Outcome of Childhood Tuberculosis in Barangay Commonwealth, Quezon City, Philippines: A Two-Year Retrospective Study
Authors: Pecson Christine , Duran Ana Liza
Published: December 2022

Background: Tuberculosis remains a public health concern worldwide. Reports on the association of factors of childhood tuberculosis with treatment outcome are limited. Objectives: To determine the epidemiology and association of factors of childhood tuberculosis with successful treatment outcome in some of the barangays of Quezon City. Methodology: This is a retrospective cohort study done at Barangay Commonwealth Health Centers including children 0-14 years old with tuberculosis registered and treated from January 1, 2013 to July 15, 2015. Socio-demographic and clinical data were obtained. Patient profile data, treatment cards and medical records were the data sources Results: A total of 267 new cases of childhood TB were analyzed. The treatment success rate was 98% (97% completed treatment, 1% cured). The rate of poor treatment outcome including default cases was 2%. There were no reported deaths or treatment failure. On univariate analysis, patients with weight gain (p=0.001) had an odds ratio of 8.085 (95% CI:1.310-49.900) to have a successful treatment outcome. On multivariate analysis, weight gain was significantly associated with treatment success (p=0.042; OR=12.5, 95% CI: 1.091, 143.244). None of the socio-economic and clinical factors studied was associated with successful treatment outcome. Conclusion: Weight gain is a factor of a successful treatment in childhood tuberculosis. Children who gained weight after treatment are more likely to have a successful treatment outcome.
Granulocyte Colony Stimulating Factor in Improving Outcomes of Neonatal Sepsis: A Meta-Analysis
Authors: Verzosa Grazielle , Yu Mary Mae Catherine , Abat-Senen Kathlynne Anne , Quilendrino Maria Isabel
Published: December 2022

Abstract Background: Neonatal sepsis complicated with neutropenia increases risk of mortality by 50%. The immature neutrophil production of neonates is often overwhelmed by severe infection. Granulocyte colony stimulating factor (G-CSF), a naturally occurring cytokine used to support neutrophil recovery during chemotherapy, is a possible treatment that can improve outcomes of neonatal sepsis. Objectives: To determine the efficacy of G-CSF in decreasing mortality and morbidity in septic neonates. Methodology: Electronic searches were conducted on online journal databases. Unpublished or ongoing studies ere sought in training institutions accredited by the Philippine Pediatric Society. The investigators included randomized control trials using G-CSF on septic neonates. Results: Twenty-two trials were identified and thirteen were assessed to be eligible for review. The studies had a total of 530 participants, with the largest having 78 subjects. Relative risks (RR), mean differences (MD) and standard mean differences (SMD) with 95% confidence intervals (CI) using the fixed effect model and random effects model were reported in the results. There was a significant decrease in mortality (RR 0.69, 95% CI 0.48 to 0.99) with a greater reduction for preterm neonates, low birth weight neonates and neutropenic neonates. There was no significant reduction in morbidities caused by neonatal sepsis. Conclusions: There is moderate quality evidence that suggests that G-CSF as an adjunct treatment for neonatal sepsis significantly decreases mortality with greater benefit to preterm neonates, low birth weight neonates and those with baseline neutropenia. The studies did not show any benefit in reducing sepsis-related morbidity.
Profile and Treatment Outcome of Patients with Infective Endocarditis Admitted in a Pediatric Medical Center From 2005-2016
Authors: Pasaoa Maribel
Published: December 2022

Background: Infective Endocarditis (IE) is an infection of the endocardial surface of the heart. It remains a life threatening infection among extremes of ages and erroneous or late diagnosis may lead to serious consequences. Objective: To determine the clinical profile and treatment outcomes of pediatric patients with IE admitted in a pediatric medical center. Methods: This is a retrospective descriptive study on pediatric patients (0-18 years old) diagnosed with IE from January 2005 to June 2016. Patients’ medical records that satisfied the criteria for IE based on Modified Duke Criteria were included in the study. Results: A total of 37 charts were reviewed with male to female ratio of 1:1. Most common chief complaint and physical finding were difficulty of breathing and tachycardia,respectively.Cardiac murmur was appreciated upon diagnosis except in one patient. 70% had ventricular septal defect and 24% had rheumatic heart disease. Most common associated non-cardiac condition was the presence of dental caries, while only 11% had history of previous cardiac surgeries. 2-Dimensional Echocardiography (2D-Echo) showed vegetation in 97.2% and 49% had positive growth in blood culture. Most common isolate was Streptococci. Empiric therapy included penicillin G (84%) with gentamicin (76%). Complications noted were brain infarct,pericarditis and pulmonary embolism. Majority were managed medically, 7 patients (19%) had vegetectomy and 9(24%)died during hospitalization. Conclusion: IE is a common complication of congenital heart disease.High index of suspicion is warranted for the early management and prevention of morbidity and mortality.
Microbiologic Profile and Predictors of Severe Outcome of Pediatric Cancer with Febrile Neutropenia Admitted at a Tertiary Medical Center
Authors: Panes Andy , Villar Cherry May , Madrid Mary Antonette
Published: December 2022

Background: The treatment of pediatric cancer has advanced dramatically. With the discovery of newer, more potent chemotherapeutic agents, patients are confronted with severe and prolonged degrees of neutropenia, which has inherent consequences. Objective: The study aimed to determine common microbial isolates and predictors of severe outcome of pediatric cancer patients with febrile neutropenia aged 0-18 years old admitted at a tertiary hospital. Methods: This was a cross-sectional study on pediatric cancer patients with febrile neutropenia admitted at the Philippine Children’s Medical Center from March 1,2017 to September 30,2017.The clinical presentations of subjects were noted. Patients were categorized as to the presence or absence of severe outcomes. Common microbial isolates were noted. Predictors of severe outcome were identified using stepwise logistic regression analysis. Results: Out of 105 enrolled patients, 32 developed severe outcomes. The most common isolates were Klebsiella pneumoniae followed by Escherichia coli and Candida species. Univariate analysis showed that acute myelogenous leukemia (p-value: 0.0195), treatment relapse (p-value: 0.0131), ANC on admission 7 days during admission (p-value: 0.0001), non-response to empiric antibiotics (pvalue:0.0001), microbiologically-defined infection (MDI, p-value: 0.0001), fever without a focus p-value:0.001), bloodstream infection (p-value: 0.0192), unknown focus of infection (p-value: 0.0058), and a positive culture (p-value: 0.0001) were related to a severe outcome. None of these predictive variables, however, were statistically significant on multivariate logistic regression analysis. Conclusion: K. pneumoniae, E. coli and Candida were the predominant organisms identified in febrile neutropenic cancer patients in our institution. Although AML, treatment relapse, profound neutropenia, fever of >7 days during admission, nonresponse to empiric antibiotics, MDI, fever without a focus, bloodstream infection, unknown focus of infection and a positive culture were related to a severe outcome, multivariate regression analysis did not show these to be significant.
Effectiveness of Digital Media Technology-based Interventions on HIV & STI Risk Reduction Among Young People: A Meta-Analysis
Authors: Tarnate Paul Sherwin , Senen Kathlynne Anne , Serrano Keith Roger , Torres-Ticzon Vanessa-Maria
Published: December 2022

Background: Prevention strategies delivered through digital media technology (DMT) have been developed to reduce HIV incidence among young people. However, no best-practice DMT intervention strategies exist in handling HIV prevention programs among young people. Objectives: To determine the effectiveness of DMT-based interventions in reducing risk-taking behaviours among young people that may predispose them to acquiring HIV and other sexually transmitted infections. Subjects and Selection Criteria: Randomized controlled trials and quasi-experimental studies with rigorous controls comparing DMT-based interventions and controls on reducing risk-taking behaviors among young people aged 10-24 years were included. Data Collection: Search methods were done on the following: MEDLINE, CENTRAL, Trials Register, Google Scholar, ScienceDirect, TRIP database, HERDIN, reference lists, & local databases until December 2017. Analysis: Statistical analysis was done using Review Manager Version 5.3, heterogeneity examined, and analyses done under random effects model. Condom use, sexual behavior, number of sexual partners, STI testing, and sexual health knowledge in standardized effect sizeswere calculated with 95% confidence intervals. Data were analyzed in subgroups: Didactics, Modules, Virtual decision-making. Main Results: Identified sixteenstudies with 7925 subjects comparing DMT interventions and controls. DMT interventions significantly increased condom use (d=0.29, 95% CI 0.18-0.41; p<0.00001), particularly in Didacticssubgroup; and decreased frequency of sexual behavior (d=0.16, 95% CI 0.06-0.26; p=0.002), particularly in Virtual decision-making subgroup.Data significant but heterogeneous for improved sexual health knowledge.There was no statistical difference for decreased number of sexual partners and STI testing. Conclusions: DMT-based interventions on condom use and frequency of sexual behavior were noted to be effective in reducing risk-taking behaviors among young people.These findings can be appropriately adapted for use in HIV/STI prevention campaigns.
Comparison of Various Methods of Detection of Hypoxemia and Correlation of Hypoxemia with Clinical Features among Pediatric Patients 3 Months to 5 Years Old with Community-Acquired Pneumonia at a Tertiary Hospital Emergency Room
Authors: Pantig Francesca Mae , Gatchalian Salvacion
Published: December 2022

Introduction: Pulse oximetry is frequently utilized as a rapid, non-invasive, point-of-care alternative to arterial blood gas analysis in measuring oxygen saturation of children with pneumonia. Objectives: To compare portable fingertip pulse oximetry saturation (SpO2PF), handheld pulse oximetry saturation (SpO2H) and arterial oxygen saturation (SaO2) in detection of hypoxemia, and correlate hypoxemia with clinical features in children with pneumonia. Methodology: This was a prospective, observational, cross-sectional study involving patients 3 months to 5 years old with pneumonia. Oxygen saturation was measured using a portable fingertip pulse oximeter, a handheld pulse oximeter, and arterial blood gas analysis. Results: Eighty-six children were included. SpO2 PF underestimated oxygen levels by 0.126% (95% CI -0.240 to 0.491), while SpO2H underestimated it by 0.323% (95% CI -0.075 to 0.721). Between portable and handheld readings, the mean difference was 0.198% (95% CI -0.089 to 0.484). Across the three methods, limits of agreement ranged from -3.388 to +4.035%. There was no statistically significant difference in variance among the three measurements. Children with tachypnea (cOR 2.623, 95% CI 1.06 – 6.48, p = 0.037), difficulty breathing (cOR 6.316, 95% CI 1.96 – 20.34, p = 0.002), and subcostal retractions (cOR 2.842, 95% CI 1.05 to 7.69, p = 0.040) were more likely to have hypoxemia. Conclusion: Pulse oximetry closely correlates with arterial blood gas analysis within acceptable limits of agreement and with no significant differences in variance among measurements. Difficulty breathing, tachypnea and subcostal retractions were significantly more likely to be observed in hypoxemic children.
Uso de inhibidores de tirosina quinasa en carcinoma medular de tiroides
Authors: Luca Romina , Tsou Florencia , Do Pico Florencia , Rivero Sergio , Falco Agustín , O’Connor Juan Manuel , Chacón Matías , Chacón Reinaldo
Published: December 2022

El cáncer medular de tiroides (CMT) corresponde al 5% de los tumores de la glándula tiroides. El único tratamiento curativo es la cirugía. En pacientes con compromiso locorregional o a distancia, la enfermedad puede evolucionar en forma indolente o bien con una rápida progresión de síntomas, requiriendo tratamiento sistémico. Si bien el CMT se caracteriza por tener escasa respuesta a la quimioterapia (QT), la evidencia actual en estudios aleatorizados demostró que los inhibidores de tirosina quinasa (ITQ) han demostrado beneficio en supervivencia libre de progresión (SLP).

Se analizaron 6 pacientes con un seguimiento mediano de 29 meses. Todos presentaron más de dos sitios metastásicos. Dos requirieron tratamientos locorregionales (quimioembolización y RT). Los ITQ más utilizados fueron: vandetanib (3), sorafenib (2) y sunitinib (1). Un 50% inició tratamiento con dosis plenas y 3 requirieron reducción de dosis debido a toxicidad G3-G4. El intervalo libre de progresión (ILP) mediano, luego del inicio con ITQ, fue de 4.1 meses.
Carcinoma epidermoide de orofaringe
Authors: Cayol Federico , Pucella Inés , Figari Marcelo , Lastiri José M.
Published: December 2022

Los carcinomas epidermoides de cabeza y cuello (CECC), son un grupo poco frecuente de neoplasias, en los Estados Unidos representan el 3.2% de todos los cánceres1,2.

Si bien su frecuencia global se encuentra en disminución, los tumores localizados en la orofaringe han aumentado de forma considerable2.

El virus del papiloma humano (HPV) es responsable de este aumento.

Se ha descripto que los tumores de orofaringe, asociados al HPV, ocurren en pacientes más jóvenes, con enfermedad de bajo volumen a nivel del tumor primario, pero elevada incidencia de metástasis ganglionares, con adenopatías quísticas2,3.

La detección del virus del HPV, por inmunohistoquímica (IHQ) o por reacción en cadena de la polimerasa (PCR) son factores pronósticos importantes que siempre deben ser tenidos en cuenta para el tratamiento de estos tumores3.
BOOSTING STUDENTS’ SPEED READING THROUGH THE SCANNING AND SKIMMING METHOD AT SMPN 1 PA’JUKUKANG
Authors: Dewi Hasrawati , Khaerati Syam Ummi , Ariana
Published: December 2022

The speed reading ability of grade VIII E SMPN 1 Pa'jukukang students was still lacking. One of the reasons for the lack of students' ability to read quickly was due to the application of inappropriate learning techniques. In learning, the teacher only uses the lecture method so that students feel bored in the learning process. Therefore, appropriate learning techniques are needed to overcome these problems. Learning to read quickly with scanning and skimming techniques can be used as a way to improve students' speed reading skills.The results showed that there was an increase in the speed reading ability of class VIII E SMPN 1 Pa'jukukang students after participating in speed reading lessons using scanning and skimming techniques. The improvement achieved is from diagnostic test with very not good, and in cycle 2 it becomes good category. The increase in students' speed reading ability can be seen from the results of the reading speed test in the diagnostic test (DT), first cycle, and second cycle. The result of the effective reading speed in the pre cycle was 99 wpm and in the first cycle the average was 132 wpm or an increase of 32.67% from the DT. Then in cycle II the average effective reading speed of students was 172 wpm or an increase of 30.30% from cycle I. The increase in effective reading speed from DT to cycle II was 73.73%. The results obtained indicate that learning to read quickly using scanning and skimming techniques for class VIII E SMPN 1 Pa'jukukang has been successful.
Suggestions that can be given include: (1) It is hoped that teachers can apply various kinds of appropriate learning techniques, especially in learning to read quickly so that students' speed reading abilities can be optimal. (2) Skimming and scanning techniques can be an alternative when learning to read quickly because they can improve, facilitate, and motivate students to read quickly.
DEVELOPMENT OF MARKETING OF EDUCATIONAL SERVICES BASED ON APPLICATION OF NETIQUETTE PRINCIPLES IN DISTANCE LEARNING
Authors: LYSYTSIA N. , BYELIKOVA YU.
Published: December 2022

In modern conditions, Ukrainian institutions of higher education found themselves in a situation of military aggression, which is the reason for the transfer of students’ education to the online space. Such changes impose new requirements on marketing of educational services aimed both at attracting new consumers and at keeping and preserving those who are already studying. Transformations of approaches in marketing of education are a consequence of its development. The development of marketing of educational services during distance online learning is impossible without the introduction of modern digital technologies and involves taking into account the rules of netiquette. The application of the principles of netiquette in distance learning will contribute to the resolution of contradictions in marketing of educational services and its development. This determines the relevance of the chosen research topicality. The purpose of the study is to determine the principles of netiquette as a basis for the development of marketing of educational services in the process of distance learning. The work uses such research methods as the method of logical generalization, the method of analysis and synthesis, the method of content analysis, and the method of focus group interview. The result of the conducted research is the development of general principles of netiquette in the organization of distance learning, taking into account the specifics of educational services. The concept of relationship marketing, provisions on distance learning and classic general principles of netiquette were used as a theoretical basis for the substantiation of these principles. The practical basis for the conclusions was the analysis of cases of US universities regarding netiquette policies, as well as the results of a focus group interview with students of institutions of higher education regarding the norms and rules of behavior in the Internet space during the interaction of teachers and students in the process of distance learning. The practical significance of the application of the rules of netiquette is that it ensures digital freedom of communication, attracts a larger segment of consumers of the educational service and will contribute to the formation of a new type of academic community.
TRANSFORMATION OF UKRAINIAN YOUTH VALUES IN TIMES OF CRISIS
Authors: LOLA YU. , POLIAKOVA H.
Published: December 2022

The value system of a certain society is characterized by stability, transmitted from generation to generation and determines the direction of the socio-economic, political development of the country. In a fragile, non-linear and incomprehensible globalized world, a shift in society’s values can be triggered by global upheavals that threaten the survival of humans as a biological species. In the 21st century, society feels the danger of war, the threat of the spread of dangerous viruses, and the digitalization of all human life. The purpose of the conducted research is to identify the main values of Ukrainian youth and their transformation in the conditions of economic crises and war danger. Sociological research was conducted to verify hypotheses as to accelerating the transformation of Ukrainian youth values. The first wave of research on the value orientations of Kharkiv student youth was conducted in March 2014, similar research was conducted during November 2020 – January 2021, as well as in April-May 2022. The results showed that absolute and family values traditionally have a high level of priority for Ukrainian youth, regardless of living conditions and external factors. However, changes have taken place within value groups. With the aggravation of the military danger, the values of freedom, honesty, and preservation of life came to the fore. During the military threat, the importance of the group of civic and national values increased significantly. Among the national ones, the greatest growth was gained by the state independence of Ukraine, patriotism, readiness to defend the Motherland, love for the native culture, language, and traditions. Digital values have shown sufficient stability of results compared to pre-war times. Digital government services and digital technologies to improve energy efficiency have grown. The results of the study can be useful for building visions and strategies for the development of higher education institutions, modern youth regional policy.
Optimalisasi Data Center Dengan Mengembangkan Virtualisasi Server (Studi Kasus : UIN Sultan Syarif Kasim Riau)
Authors: Afriyanti Liza
Published: December 2022

Perkembangan teknologi dari sisi perangkat keras maupun perangkat lunak mengalami perkembangan yang kian pesat. Saat ini penggunaan data center adalah sebagai fasilitas yang digunakan sebagai lokasi penempatan beberapa server dan sistem database yang saling terintegrasi untuk pengolahan data yang berukuran besar. Instansi perguruan tinggi yang memiliki mahasiswa, dosen, dan pegawai dalam jumlah besar membutuhkan perangkat pengelolaan server pada data center sehingga pengembangan dan pengelolaan sistem aplikasi serta teknologi informasi dapat dikelola secara maksimal.  Universitas Islam Negeri Sultan Syarif Kasim Riau (UIN Suska Riau) merupakan salah satu perguruan tinggi yang menggunakan Information and Communication Technology (ICT) sebagai pendukung utama sarana dan prasarana proses pendidikan dan pengajaran. Seiring dengan perkembangan sistem aplikasi yang ada di UIN Suska Riau, maka kebutuhan server kian bertambah. Berdasarkan permasalahan tersebut maka perlu dilakukan optimalisasi pemanfaatan data center dengan melakukan teknologi virtualisasi server sehingga dapat mengatasi permasalahan keterbatasan perangkat keras yang tidak sebanding dengan peningkatan kebutuhan sistem aplikasi. Hasil akhir dari penelitian ini adalah pengembangan virtualisasi server untuk mendukung optimalisasi pemanfaatan data center di lingkungan UIN Suska Riau.
Rancang Bangun Sistem E-Learning Berbasis Web Di SMA Negeri 1 Waingapu
Authors: Garamesa Peni , Kalaway Rambu Yetti , Sitaniapessy Desy Asnath
Published: December 2022

Dampak teknologi informasi dan komunikasi dalam dunia pendidikan semakin terasa dan sejalan dengan  pergeseran pola pembelajaran dari pendidikan tradisional tatap muka ke pendidikan yang lebih terbuka dan termediasi. Teknologi informasi sangat cepat berkembang sesuai dengan kebutuhan manusia, Salah satunya dalam bidang pendidikan yang banyak digunakan untuk mendapatkan informasi diberbagai belahan dunia tanpa terhalang oleh jarak dan waktu dimanapun bisa digunakan. Seiring dengan adanya kebutuhan dari aktivitas belajar online dalam dunia Pendidikan teknologi telah banyak menghasilkan inovasi baru dalam bentuk digital yang biasa kita kenal dengan sebutan e-learning. E-learning merupakan alat pendukung dalam kegiatan belajar mengajar. Penelitian ini bertujuan untuk menganalisis dan merancang e-learning pada SMAN 1 Waingapu sebagai alat pendukung dalam proses belajar mengajar. Metode penelitian yang digunakan antara lain adalah waterfall. Sedangkan pada metode pengumpulan data dilakukan dengan wawancara, observasi serta tinjauan pustaka ke dalam penelitian terkait. Dalam membangun sistem e-learning Bahasa pemograman yang digunakan adalah PHP dan MySQL sebagai database. Dengan metode sistem e-learning dapat menumbuhkan intensitas antara pengajar dan siswa serta mempermudah dalam mendapatkan materi pembelajaran dimanapun dan tanpa keterbatasan ruang dan waktu.
Dampak Rasio Keuangan Terhadap Harga Saham Perusahaan Barang Konsumsi Yang Terdaftar Di Bursa Efek Indonesia
Authors: Putri Via Andani , Yustisia Natali
Published: December 2022

Penelitian ini bertujuan untuk menganalisis pengaruh Quick Ratio, Debt to Equity Ratio, Total Asset Turnover dan Return on Equity terhadap harga saham. Populasi yang digunakan dalam penelitian ini yaitu perusahaan barang konsumsi yang terdaftar  di Bursa Efek Indonesia periode 2015-2019. Teknik pengambilan sampel yang digunakan adalah purposive sampling dan didapatkan sampel sebanyak 26 perusahaan. Metode analisis yang digunakan adalah analisis regresi data panel. Hasil penelitian menunjukkan bahwa Debt to Equity Ratio berpengaruh signifikan negatif terhadap harga saham sedangkan Return on Equity berpengaruh signifikan positif terhadap harga saham. Sebaliknya, Quick Ratio dan Total Asset Turnover tidak berpengaruh signifikan terhadap harga saham. Sementara itu, nilai adjusted R-square sebesar 0,9619. Hal tersebut menjelaskan bahwa pengaruh variabel Quick Ratio, Debt to Equity Ratio, Total Asset Turnover dan Return on Equity terhadap harga saham sebesar  96,19%.
Pengaruh Gaya Kepemimpinan, Motivasi Kerja Dan Disiplin Kerja Terhadap Kinerja Karyawan
Authors: Wulandari Eka , Prastiwi Iin Emy , Romdhoni Abdul Haris
Published: December 2022

Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh gaya kepemimpinan, motivasi kerja, disiplin kerja terhadap kinerja karyawan PT Hermosa Garment International. Penelitian ini menggunakan pendekatan deskriptif kuantitatif. Teknik yang dikumpulkan berupa data primer melalui kuesioner yang dibagikan kepada responden yang disebut dengan kuesioner. Teknik pengumpulan data menggunakan teknik purposive sampling yaitu teknik pengambilan sampel dengan pertimbangan tertentu yaitu menggunakan kriteria tertentu seperti karyawan yang sudah bekerja lebih dari 1 tahun, penelitian ini dilakukan dengan menyebarkan kuesioner dan dilakukan oleh 39 karyawan dari 214 karyawan di PT Hermosa. Garmen Internasional.

Dari hasil penelitian bahwa variabel gaya kepemimpinan tidak berpengaruh signifikan terhadap kinerja pegawai, hasil persamaan regresi berganda diperoleh nilai sebesar 0,108, dengan nilai 0,887 lebih kecil dari t tabel 2,03011 dan nilai Sig sebesar 0,381 lebih besar dari 0,05 , maka Ha ditolak. Variabel motivasi kerja tidak berpengaruh secara signifikan terhadap kinerja karyawan yaitu nilai persamaan regresi berganda menghasilkan nilai sebesar 0,153, dengan nilai t hitung sebesar 1,437 lebih kecil dari t tabel 2,03011 dan nilai Sig sebesar 0,160 lebih besar dari 0,05 maka Ha ditolak. Variabel disiplin kerja berpengaruh signifikan terhadap kinerja karyawan yaitu nilai dari hasil persamaan regresi berganda diperoleh nilai sebesar 0,582, dengan nilai sebesar 3,727 lebih besar dari t tabel 2,03011 dan nilai Sig sebesar 0,001 lebih kecil dari 0,05, maka Ha diterima. Gaya kepemimpinan, motivasi kerja dan disiplin kerja secara bersama-sama (simultan) berpengaruh signifikan terhadap kinerja karyawan pada PT Hermosa Garment International.
Tinjauan Hukum Islam terhadap Pengadaan Walimatul ‘Ursy pada Masa Pandemi Covid-19
Authors: Afrohah Afrohah
Published: December 2022

Di Indonesia Pandemi Covid-19 dianggap sebagai bencana Nasional sehingga diberlakukan Pembatasan Sosial Berskala Besar dengan membatasi kegiatan tertentu dalam masyarakat. Salah satunya adalah penyelenggaraan Walimatul ‘Ursy yang merupakan anjuran Agama Islam dan Budaya yang sudah mendarah daging di Indonesia. Banyak Aparat Pemerintah Daerah yang melarang pengadaan Walimatul ‘Ursy pada Masa Pandemi Covid-19 karena dianggap sebagai pelanggaran. Salah satunya di Kabupaten Wonogiri, Satgas Covid-19 Kabupaten Wonogiri sering membubarkan warga yang nekat menggelar Walimatul ‘Ursy sehingga banyak masyarakat yang dilema antara harus mengadakan Walimatul ‘Ursy atau tidak. Tujuan dari penelitian ini adalah untuk menganalisa tentang Tinjauan Hukum Islam terhadap Pengadaan Walimatul ‘Ursy Pada Masa Pandemi Covid-19 (Studi Kasus Di Kecamatan Jatipurno Kabupaten Wonogiri). sebagai sumbangsih peneliti untuk kemudian dijadikan rujukan masyarakat. Jenis penelitian yang digunakan adalah menggunakan pendekatan kualitatif. Penelitian ini dilakukan selama 4 bulan, yakni bulan Maret 2021 sampai Juni 2021. Hasil penelitian ini dapat disimpulkan bahwa Pengadaan Walimatul ‘Ursy pada Masa Pandemi Covid-19 di Kecamatan Jatipurno Wonogiri adalah mengikuti Regulasi Peraturan Pemerintah (Ulil Amri) yang berlandaskan kemaslahatan rakyat. Dalam Pengadaanya dinilai sudah cukup tertib, Sehingga status hukum pelaksanaan Walimatul ‘Ursy pada Masa Pandemi Covid-19 di Kecamatan Jatipurno Wonogiri adalah boleh (Mubah), dengan cacatan mendapatkan izin resmi dari Pemerintah setempat dan sanggup mematuhi syarat dan ketentuan teknis pelaksanaannya.
Diskursus Penerapan Metode Omnibus Law dalam Pembentukan Undang-Undang No. 11 Tahun 2020 Tentang Cipta Kerja
Authors: Kurniyasih Fajar , Setyorini Ika
Published: December 2022

The application of an Omnibus Law method first full-length time is used in Indonesia in the formation of  the Law No. 11 Year 2020 about Cipta Kerja. This certainly need to examined will the adoption of an Omnibus Law method in the formation of the Law Cipta Kerja in accordance with the procedures and the principles for the formation of legislations in Indonesia.

This study using qualitiative methodology through approach normative juridical that have been analyzed a sort of descriptive set with conducted research on the application of an Omnibus Law method in the of the Law Cipta Kerja and legislations which are related. In this context discusses how the law in the formation of an omnibus legislation, in Indonesia the application of an Omnibus Law method in the of the Law Cipta Kerja in the formation and the discourse.

Through this research, the results obtained that the Omnibus Law Method has been substantively carried out in Indonesia in the formation of several laws and regulations and the position of Omnibus Law is as a method. An Omnibus Law has not been regulated in of Law No. 12 Year 2011 that has been converted in of Law No. 15 Year 2019 at about rule the formation of legislation, so there will be a different on a number of clauses in the preparation of the Law Cipta Kerja. This then creates a discourse in its application which has implications for the quality of The Law Cipta Kerja.
Peran Teknologi Pendidikan pada Pembelajaran PAI di Masa Pandemi Covid-19
Authors: Ardita Cevina Rinda , Salsabila Unik Hanifah , Syarofah Alinda , Pahlevie Muhammad Syafrizal , Risam Muhammad Rizky Nur
Published: December 2022

Adanya peristiwa atau wabah Covid-19 membawa dunia pada percepatan penggunaan teknologi dalam kehidupan sehari-hari. Hal tersebut tidak dapat dihindari, dalam dunia pendidikan pun demikian terkhusus pembelajaran Pendidikan Agama Islam. Pada penelitian kali ini kami menggunakan metode studi literatur dengan menelaah jurnal-jurnal yang berkaitan dengan teknologi pembelajaran dan relevan dengan keadaan pandemi Covid-19 sehingga didapatkan data-data yang dapat memperkuat penelitian kami. Pada penelitian kali ini akan dijabarkan bagaimana teknologi berperan dalam PAI dimasa pandemi Covid-19, selain itu disajikan manfaat, contoh-contoh media yang dapat digunakan dan juga dampak – dampak yang timbul dari pengimplementasian teknologi tersebut. Dari penelitian tersebut dihasilkan bahwa teknologi ini dapat dijadikan sebagai suatu media pembantu bagi seorang pendidik dalam pelaksanaan pembelajaran. Peran dari teknologi ini pada dasarnya juga harus di imbangi dengan adanya pemahaman atau penguasaan dalam pengimplementasiannya. Kemudian platfrom yang dapat membantu dalam proses pembelajaran daring yakni e-learning, google classroom, google meet, Zoom, Whatsapp, dsb. Media audiovisual (google meet dan Zoom) dirasa dapat berpeluang lebih maksimal dalam pembelajaran jika dalam teknisnya ditangani dengan baik. Sedangkan jika hanya media berbasis audio atau teks saja dirasa kurang memberikan kesempatan terjadi interaksi yang optimal. Akan tetapi untuk penugasan media audio dan teks ini lebih efisien dan mudah tersampaikan.
Faktor-Faktor yang Mempengaruhi Volume Penjualan Pada Toko Delta Convection, Pedan, Klaten
Authors: Prastiwi Iin Emy , Romdhoni Abdul Haris , Widayati Yuliana Rikha
Published: December 2022

Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh kualitas produk dan pemasaran syariah terhadap volume penjualan kepada konsumen pada toko Delta Konveksi Pedan Klaten. Penelitian ini menggunakan pendekatan deskriptif kuantitatif. Teknik yang dikumpulkan berupa data primer melalui kuesioner yang dibagikan kepada responden yang disebut dengan kuesioner. teknik pengumpulan data menggunakan teknik purposive sampling yaitu teknik penentuan sampel dengan pertimbangan tertentu yaitu dengan menggunakan kriteria tertentu seperti data pembelian konsumen tahun 2019 sampai 2020, penelitian ini dilakukan dengan menyebarkan kuesioner dan dilakukan oleh 76 konsumen dari 310 konsumen di toko Delta Multi Convection. dari hasil penelitian bahwa variabel kualitas produk tidak berpengaruh signifikan dari hasil penelitian variabel kualitas produk tidak berpengaruh signifikan terhadap volume penjualan dari hasil penelitian variabel kualitas produk tidak berpengaruh signifikan terhadap penjualan volume. Diperoleh sama dari hasil penelitian bahwa variabel kualitas produk tidak berpengaruh signifikan terhadap volume penjualan yaitu diperoleh hasil = 1,931 yang mana dari hasil penelitian variabel kualitas produk tidak berpengaruh signifikan terhadap volume penjualan yaitu hasil yang diperoleh dihitung = 1,931 yang berarti t hitung < t tabel (1,931 < 1,992) dan sig t = 0,057 > 0,05, maka Ho diterima dan Ha ditolak. Variabel pemasaran syariah berpengaruh signifikan terhadap volume penjualan yaitu diperoleh hasil t hitung = 6,454 yang berarti t hitung > dari t tabel (6,454 > 1,992) dan sig t = 0,000 < 0,05 maka Ho ditolak dan Ha diterima. kualitas produk dan pemasaran syariah berpengaruh secara simultan terhadap volume penjualan.