bluuebunny/crossref_metadata_2025 huggingface dataset:
Neuropeptide S receptor in GtoPdb v.2023.1
Authors: Caló Girolamo , Civelli Olivier , Reinscheid Rainer K. , Ruzza Chiara
Published: May 2023

The neuropeptide S receptor (NPS receptor) responds to the 20 amino-acid peptide neuropeptide S derived from a precursor (NPS, P0C0P6). NPS activates its receptor at low nanomolar concentrations elevating intracellular cAMP and calcium levels [71]. Currently, some peptidic and small molecule NPS receptor antagonists are available as research tools [27, 79, 8, 59]. No NPS receptor ligands are currently used clinically.
Succinate receptor in GtoPdb v.2023.1
Authors: Davenport Anthony P. , Hanson Julien , Liew Wen Chiy
Published: May 2023

Nomenclature as recommended by NC-IUPHAR [8]. The succinate receptor (GPR91, SUCNR1) is activated by the tricarboxylic acid (or Krebs) cycle intermediate succinate and other dicarboxylic acids with less clear physiological relevance such as maleate [17]. Since its pairing with its endogenous ligand in 2004, intense research has focused on the receptor-ligand pair role in various (patho)physiological processes such as regulation of renin production [17, 39], ischemia injury [17], fibrosis [25], retinal angiogenesis [34], inflammation [25, 23], immune response [32], obesity [44, 26, 21], diabetes [42, 22, 39], platelet aggregation [38, 36] or cancer [28, 46]. The succinate receptor is coupled to Gi/o [11, 17] and Gq/11 protein families [31, 17, 40]. Although the receptor is, upon ligand addition, rapidly desensitized [19, 31], and in some cells internalized [17], it seems to recruit arrestins weakly [10]. The cellular activation of the succinate receptor triggers various signalling pathways such as decrease of cAMP levels, [Ca2+]i mobilization and activation of kinases (ERK, c-Jun, Akt, Src, p38, PI3Kβ, etc.) [12]. The receptor is broadly expressed but is notably abundant in immune cells (M2 macrophages [40, 21], monocytes [32], immature dendritic cells [32], adipocytes [44], platelets [38, 36], etc.) and in the kidney [17].
Oxoglutarate receptor in GtoPdb v.2023.1
Authors: Davenport Anthony P. , Liew Wen Chiy
Published: May 2023

Nomenclature as recommended by NC-IUPHAR [3].
QRFP receptor in GtoPdb v.2023.1
Authors: Bagnol Didier , Bonner Tom I. , Carlebur Myrna , Davenport Anthony P. , Foord Stephen M. , Fukusumi Shoji , Granata Riccarda , Larhammar Dan , Leprince Jérôme , Maguire Janet J. , Primeaux Stefany D. , Vaudry Hubert
Published: May 2023

The human gene encoding the QRFP receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the QRFP receptor [19]; QRFPR, formerly known as the Peptide P518 receptor), previously designated as an orphan GPCR receptor was identified in 2001 by Lee et al. from a hypothalamus cDNA library [17]. However, the reported cDNA (AF411117) is a chimera with bases 1-127 derived from chromosome 1 and bases 155-1368 derived from chromosome 4. When corrected, QRFPR (also referred to as SP9155 or AQ27) encodes a 431 amino acid protein that shares sequence similarities in the transmembrane spanning regions with other peptide receptors. These include neuropeptide FF2 (38%), neuropeptide Y2 (37%) and galanin Gal1 (35%) receptors. QRFP receptor was identified as a Gs-coupled GPCR [6, 14] that's activated by the endogenous peptides QRFP43 (43RFa) and QRFP26 (26RFa) [6, 14, 11]. However, Gq- and Gi/o-mediated signaling was also reported [11, 25]. Two naturally occurring mutations in the human QRFP receptor lead to distinct and opposite 26RFa-evoked signaling bias [20].
Proteinase-activated receptors in GtoPdb v.2023.1
Authors: Bunnett Nigel , DeFea Kathryn , Hamilton Justin , Hollenberg Morley D. , Ramachandran Rithwik , Trejo JoAnn
Published: May 2023

Proteinase-activated receptors (PARs, nomenclature as agreed by the NC-IUPHAR Subcommittee on Proteinase-activated Receptors [39]) are unique members of the GPCR superfamily activated by proteolytic cleavage of their amino terminal exodomains. Agonist proteinase-induced hydrolysis unmasks a tethered ligand (TL) at the exposed amino terminus, which acts intramolecularly at the binding site in the body of the receptor to effect transmembrane signalling. TL sequences at human PAR1-4 are SFLLRN-NH2, SLIGKV-NH2, TFRGAP-NH2 and GYPGQV-NH2, respectively. With the exception of PAR3, synthetic peptides with these sequences (as carboxyl terminal amides) are able to act as agonists at their respective receptors. Several proteinases, including neutrophil elastase, cathepsin G and chymotrypsin can have inhibitory effects at PAR1 and PAR2 such that they cleave the exodomain of the receptor without inducing activation of Gαq-coupled calcium signalling, thereby preventing activation by activating proteinases but not by agonist peptides. Neutrophil elastase (NE) cleavage of PAR1 and PAR2 can however activate MAP kinase signaling by exposing a TL that is different from the one revealed by trypsin [87]. PAR2 activation by NE regulates inflammation and pain responses [115, 76] and triggers mucin secretion from airway epithelial cells [116].
VIP and PACAP receptors in GtoPdb v.2023.1
Authors: Fahrenkrug Jan , Goetzl Edward J. , Gozes Illana , Harmar Anthony , Laburthe Marc , May Victor , Pisegna Joseph R. , Said Sami I. , Vaudry David , Vaudry Hubert , Waschek James A.
Published: May 2023

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Vasoactive Intestinal Peptide Receptors [65, 66]) are activated by the endogenous peptides VIP, PACAP-38, PACAP-27, peptide histidine isoleucineamide (PHI), peptide histidine methionineamide (PHM) and peptide histidine valine (PHV). VPAC1 and VPAC2 receptors display comparable affinity for the PACAP peptides, PACAP-27 and PACAP-38, and VIP, whereas PACAP-27 and PACAP-38 are >100 fold more potent than VIP as agonists of most isoforms of the PAC1 receptor. However, one splice variant of the human PAC1 receptor has been reported to respond to PACAP-38, PACAP-27 and VIP with comparable affinity [30]. PG 99-465 [117] has been used as a selective VPAC2 receptor antagonist in a number of physiological studies, but has been reported to have significant activity at VPAC1 and PAC1 receptors [36]. The selective PAC1 receptor agonist maxadilan, was extracted from the salivary glands of sand flies (Lutzomyia longipalpis) and has no sequence homology to VIP or the PACAP peptides [118]. Two deletion variants of maxadilan, M65 [183] and Max.d.4 [119] have been reported to be PAC1 receptor antagonists, but these peptides have not been extensively characterised.
Glycine receptors in GtoPdb v.2023.1
Authors: Lynch Joseph. W. , Sivilotti Lucia G. , Smart Trevor G.
Published: May 2023

The inhibitory glycine receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on Glycine Receptors) is a member of the Cys-loop superfamily of transmitter-gated ion channels that includes the GABAA, nicotinic acetylcholine and 5-HT3 receptors and Zn2+- activated channels. The glycine receptor is expressed either as a homo-pentamer of α subunits, or a complex of 4α and 1β subunits [131], that contains an intrinsic anion channel. Four differentially expressed isoforms of the α-subunit (α1-α4) and one variant of the β-subunit (β1, GLRB, P48167) have been identified by genomic and cDNA cloning. Further diversity originates from alternative splicing of the primary gene transcripts for α1 (α1INS and α1del), α2 (α2A and α2B), α3 (α3S and α3L) and β (βΔ7) subunits and by mRNA editing of the α2 and α3 subunit [20, 84, 94]. Both α2 splicing and α3 mRNA editing can produce subunits (i.e., α2B and α3P185L) with enhanced agonist sensitivity. Predominantly, the adult form of the receptor contains α1 (or α3) and β subunits whereas the immature form is mostly composed of only α2 subunits [79]. The α4 subunit is a pseudogene in humans [66]. High resolution molecular structures are available for α1 homomeric, α3 homomeric, and αβ hteromeric receptors in a variety of ligand-induced conformations [19, 129, 19, 48, 49, 50]. As in other Cys-loop receptors, the orthosteric binding site for agonists and the competitive antagonist strychnine is formed at the interfaces between the subunits’ extracellular domains. Inclusion of the β-subunit in the pentameric glycine receptor contributes to agonist binding, reduces single channel conductance and alters pharmacology. The β-subunit also anchors the receptor, via an amphipathic sequence within the large intracellular loop region, to gephyrin. This a cytoskeletal attachment protein that binds to a number of subsynaptic proteins involved in cytoskeletal structure and thus clusters and anchors hetero-oligomeric receptors to the synapse [55, 89]. G protein βγ subunits enhance the open state probability of native and recombinant glycine receptors by association with domains within the large intracellular loop [125, 124]. Intracellular chloride concentration modulates the kinetics of native and recombinant glycine receptors [97]. Intracellular Ca2+ appears to increase native and recombinant glycine receptor affinity, prolonging channel open events, by a mechanism that does not involve phosphorylation [26]. Extracellular Zn2+ potentiates GlyR function at nanomolar concentrations [87]. and causes inhibition at higher micromolar concentrations (17).
A Correlation between the Number of Airborne Bacteria and Fungi using the Settle Plate Method with Temperature and Relative Humidity at the Clinical Microbiology Laboratory of Dr. Soetomo Regional General Hospital Surabaya, Indonesia
Authors: Andriana Yenni , Widodo Agung Dwi Wahyu , Endraswari Pepy Dwi
Published: May 2023

Air is an important part of human life. However, air can be contaminated with microorganisms such as airborne bacteria and fungi. Temperature and relative humidity in a room can have an impact on the quantity of airborne bacteria and fungi. This study aims to figure out the correlation between the number of airborne bacteria and fungi with temperature and relative humidity. In 15 rooms of Microbiology laboratory, NA and SDA Petri plates were placed, after incubation, the number of colonies in each plate was counted. Pearson test was conducted with SPSS to determine the correlation between temperature and relative humidity to the number of airborne bacteria and fungi. The highest number of airborne bacteria was in the reading room (352 CFU/m3), while the lowest number was in the laundry room (13 CFU/m3) and the highest number of airborne fungi was in the Mycology room (156 CFU/m3), while there were no airborne fungi found in the urine and laundry rooms. Based on the results of the Pearson test, it was found that the value of p = 0.668 (p> 0.5) showed that there was no correlation between temperature and the number of airborne bacteria and fungi. Based on the results of the Pearson test, the value of p = 0.745 (p> 0.5) showed that there was no correlation between relative humidity and the number of airborne bacteria and fungi. There is no correlation between temperature and relative humidity with the number of airborne bacteria and fungi.
Antimicrobial Resistance and Major Virulence Gene Detection in Methicillin Resistant Staphylococcus aureus in Humans and Livestock Animals of Assam: A North Eastern State of India
Authors: Deka Naba Kumar , Handique Pratap Jyoti , Borah Probodh , Konwar Pranita , Deka Geetanjali , Das Rijumani , Choudhury Mridusmita
Published: May 2023

Methicillin resistant Staphylococcus aureus (MRSA) is highly divergent antibiotic resistant bacteria earmarked as “High” in global pathogens’ priority list varying the severity and resistance geographically. Here, MRSA were screened using mecA gene with Cefoxitin and other 27 antibiotics of 19 classes using disc diffusion method from a highly humid climate of India. Multiple Antibiotic Resistance (MAR) index was calculated. Minimum Inhibitory Concentration (MIC) was determined against 11 classes of antibiotics. Detection of major virulence genes tst-1 and lukPV were done. A total of 95.24% Hospital Associated (HA)-MRSA, 56.14% Community Associated (CA)-MRSA and 82.53 % Livestock Associated (LA)-MRSA were detected. Cefoxitin, Oxacillin, Ciprofloxacin, Fusidic acid and Ticarcillin-Clavulinic acid resistance was observed in more than 60% of HA-MRSA, CA-MRSA and LA-MRSA. Across the hosts, Mupirocin, Gentamicin, Linezolid, Co-trimoxazole, and Rifampicin were found effective. Vancomycin Intermediate Staphylococcus aureus (VISA) detected in CA-MRSA & LA-MRSA. Multidrug Resistant (MDR) was found very high but extensively drug-resistant (XDR) was detected moderately. No pan drug-resistant (PDR) was detected. Virulence gene tst-1 and lukPV were detected in 7.69% and 32.69% MRSA isolates. The gene tst-1 is reported for the first time in pre and post-caesarian samples from Gynaecology department in this region with high MDR. This study showed S. aureus and subsequent prevalence of MRSA is higher in this region then national data. 2nd generation Cephalosporins were found effective which is very encouraging due to their limited uses. Detection of tst-1 in caesarian samples is a serious threat as neonatal transmission of MRSA from mother is reported.
In vitro Evaluation of the Antimicrobial Activity of Aqueous and Ethanolic Extracts of Four Medicinal Plants from Saudi Arabia
Authors: Alenezi Muneefah Abdullah
Published: May 2023

Natural compounds derived from higher plants can serve as new sources of antibacterial drugs with potentially novel mechanisms of action. Traditional medicine uses plant extracts to treat a variety of infectious disorders, including those caused by bacteria and fungi. Currently, there is a great demand for plant extracts with significant antibacterial activity. In this study, extracts from four plants—Lantana camara, Withania somnifera, Cetrariais landica, and Tribulus terrestris—were subjected to phytochemical screening, and in vitro antibacterial activity was evaluated. Phytochemical investigations revealed the presence of saponins, alkaloids, phenolics, flavonoids, carbohydrates, proteins, amino acids, glycosides, tannins, and terpenoids. The antimicrobial activities of the plant extracts were assessed using the disc diffusion method. They exhibited varied antimicrobial activities against gram-negative bacteria (E. coli and P. aeruginosa), gram-positive bacteria (B. subtilis and S. aureus), and fungi (C. albicans, A. niger, F. oxisporium, and F. solani). Lantana camara extract showed the highest phytochemical content and antimicrobial activity. These findings can be used in the pharmaceutical and alternative medicine industries to create natural bioactive compounds that are beneficial to human health.
Paradigm Shift of Sustainable Human Resource Management: A Systematic Review
Authors: Katiyar Arpana , Sachan Dr. Vivek Singh
Published: May 2023

Abstract: Sustainable management takes the concepts from sustainability and synthesizes them with the concepts of management. Sustainability has three branches: the environment, the needs of present and future generations, and the economy. Using these branches, it creates the ability of a system to thrive by maintaining economic viability and also nourishing the needs of the present and future generations by limiting resource depletion. From this definition, sustainable management has been created to be defined as the application of sustainable practices in the categories of businesses, agriculture, society, environment, and personal life by managing them in a way that will benefit current generations and future generations. Sustainable management is needed because it is an important part of the ability to successfully maintain the quality of life on our planet. Sustainable management can be applied to all aspects of our lives. For example, the practices of a business should be sustainable if they wish to stay in businesses, because if the business is unsustainable, then by the definition of sustainability they will cease to be able to be in competition. Communities are in a need of sustainable management, because if the community is to prosper, then the management must be sustainable. Forest and natural resources need to have sustainable management if they are to be able to be continually used by our generation and future generations. Our personal lives also need to be managed sustainably. This can be by making decisions that will help sustain our immediate surroundings and environment, or it can be by managing our emotional and physical wellbeing. Sustainable management can be applied to many things, as it can be applied as a literal and an abstract concept. Meaning, depending on what they are applied to the meaning of what it is can change
Real-Time Parking Assistance using Arduino and Sensors
Authors: Bhatti Ananya , Rai Amar , Siddiqui Anas Adil , Nirala Ravikant
Published: May 2023

Abstract: Automated Parking System can fulfil parking operations quickly and safely without wastage of time and energy. This study describes a scale model of an automated parking system with an LCD screen that can regulate and manage the number of vehicles that can be parked in a certain area at any given time based on the availability of parking spaces. The employment of sensors during car entry and exit is known as automatic parking. Most current systems aren't fully automated and require some amount of human interference or interaction in or with the system, according to our analysis of a few of the existing systems. We have examined some of the existing systems, and the results indicate that most of them aren't fully automated and need some amount of human involvement.
Fabrication of Mini Fire Fighting Robot
Authors: Singh Priyanshu , Pandit Priya , Vishwakarma Omprakash , Kalam Shekh , Dubey Suveer Chandra
Published: May 2023

Abstract: Fire Incident is a disaster that can potentially cause the loss of life, property damage and permanent disability to the affected victim. The Victim of Fire Incident can also suffer from prolonged psychological and trauma. Fire fighters are primarily tasked to handle fire incidents, but they are often exposed to higher risks when extinguishing fire, especially in hazardous environments such as in nuclear power plant, petroleum refineries and gas tanks. They are also faced with other difficulties, particularly if fire occurs in narrow and restricted places, as it is necessary to explore the ruins of buildings and obstacles to extinguish the fire and save the victim. With high barriers and risks in fire extinguishment operations, technological innovations can be utilized to assist firefighting. Therefore, this paper presents the design of a firefighting robot dubbed that can extinguish fire without the need for fire fighters to be exposed to unnecessary danger. It is designed to be compact in size than other conventional fire-fighting robot to ease small location entry for deeper reach of extinguishing fire in narrow space. It is also equipped with an ultrasonic sensor to avoid it from hitting any obstacle and surrounding objects, while a flame sensor is attached for fire detection. This resulted in It demonstrating capabilities of identifying fire locations automatically and ability to extinguish fire remotely at distance
Frame Fabrication of Electric Formula One Car
Authors: Shelke Prof. M. S.
Published: May 2023

Abstract: Design, fabrication, and testing of electric formula one car is presented in this paper. The design guidelines are based on the specifications set by the organizer, universities, design of the car was carried out using SOLID MODELLING system. The car was fabricated in the workshop of mechanical and manufacturing engineering. The car has been tested for its performance
Machine Learning-based Classification of Edible and Poisonous Mushrooms: A Performance Comparison
Authors: Essa Irfan Ahamed , Dhanalakshmi R.
Published: May 2023

Abstract: In the disciplines of computer vision and machine learning, classifying mushrooms is a key problem. The objective of this study is to create a machine learning model that can correctly categorise different species of mushrooms as either edible or harmful based on their visual characteristics. The Field Guide to North American Mushrooms of the Audubon Society served as the study's data source, and it includes descriptions of hypothetical samples of 23 species of gilled mushrooms from the Agaricus and Lepiota families. Each sample is categorised as either definitely edible, definitely poisonous. To create our machine learning model for this study, we combined five different algorithms: SVM, logistic regression, decision tree, random forest, and KNN. Metrics such as accuracy, precision, recall, and F1 score were used to assess each algorithm's performance. Our findings show that the random forest algorithm outperformed the other algorithms with a 95% accuracy rate. However, by employing feature selection strategies and hyperparameter tuning, we further improved our model. We were able to raise the accuracy of our model to 97% by choosing the most pertinent features and fine-tuning its hyperparameters. The outcomes of this study should offer a practical method for precisely categorising mushrooms and lowering the danger of mushroom poisoning. This paper proposes an ensemble approach utilizing five different machine learning classifiers to detect mushroom classification. The study analyzes various features, such as cap-shape, gill-colour, stem texture and ring-type & stalk features, and the finding
Combined Effect of Cow Dung Ash and Rice Husk Ash on Mechanical Performance of Concrete
Authors: Sahu Prabeen Kumar , Patel Niharika
Published: May 2023

Abstract: Rice Husk Ash (RHA) and Cow Dung Ash (CDA) are agriculturally based pozzolanic materials, these materials are available in huge quantities. This final year project report highlights and presents the results of the study on the use of Cow Dung Ash and Rice Husk Ash as partial replacement of cement in concrete. The experiments were conducted to study the impacts of adding Cow Dung Ash and Rice Husk Ash in several percentages by weight (0%, 5%, 10%, 15%, and 20%) of cement and cure for periods of 28 days before testing for compression strength. The consistency, workability, sieve analysis of aggregates were also tested in this research study. The Compressive test results are 37.75 N/mm2, 31.25 N/mm2, 31.25N/mm2 and 25.25 N/mm2 for 0%, 5%, 10% and 15% replacement of cement with Cow Dung Ash and Rice Husk Ash respectively at 28days. The Workability results gives 45mm, 49mm, 56mm, 68mm and 75mm respectively for 0%,5%, 10%, 15%, and 20% replacement of cement with Cow Dung Ash and Rice Husk Ash. The consistency test results are 0.29, 0.32, 0.36, 0.41 and 0.43 for 0%, 5%, 10%, 15% and 20% replacement of cement with Cow Dung Ash and Rice Husk Ash respectively. The bulk density results are 2452.53 kg/m3, 2370.8 kg/m3, 2380.0 kg/m3 and 2348.5 kg/m3 for 0%, 5%, 10% and 15% replacement of cement with Cow Dung Ash and Rice Husk Ash respectively. The main highlights, it should be highlighted that the more quantity of water is required to standard consistency as the percentages of Cow Dung Ash and Rice Husk Ash are added. Dung Ash and Rice Husk Ash concrete is recommended for use when a ten percentage (10%) of Cow Dung Ash and rice husk ash are not exceeded
An Overview of IoT and ML-Based Emotion Recognition Systems
Authors: Sakri Leena I. , Bendigeri Deepa , Hegde Rachana , Hegde Anushree , Anvekar Shreya , Huddar Amogh
Published: May 2023

Abstract: Emotion recognition has emerged as a crucial research area in recent years due to its potential applications in various fields such as healthcare, marketing, and entertainment. In this study, we propose a novel approach to emotion recognition using the Internet of Things (IoT) and Machine Learning (ML) techniques. Our system consists of IoT devices equipped with sensors that capture physiological signals such as heart rate, skin conductance, and facial expressions. These signals are pre-processed and fed into an ML model for emotion classification. We evaluate our system on a publicly available dataset and achieve an accuracy of over 90%. Our results demonstrate the feasibility and effectiveness of using IoT and ML for emotion recognition, which can have significant implications for various industries. The proposed system can be extended to real-world applications such as personalized healthcare, customer feedback analysis, and content recommendation.
Career Choice of The Students, What is Important?
Authors: Zulfikarijah Fien , Mohyi Achmad
Published: May 2023

This study aims to determine the factors considered by students in choosing a career after graduating from college. The research population is students of the 4 largest universities in Malang, they are Brawijaya University, State University of Malang, University of Muhammadiyah Malang and State Islamic University of Malang. The sample of the study was 200 respondents with details of each university 50 respondents, respondents who filled out the complete questionnaire were 134. The analysis tool was factor analysis with 24 variables originating from the voice of respondents. From the data analysis process, 16 variables were worthy of analysis and grouped into 6 factors. The results showed that there were 6 factors for student career choice are: financial, job information, opportunity, social environment, challenge and interest, with financial being the dominant factor.
Understanding How Management Students Choose their Career
Authors: Khwarizmi Raja , Tsabita Khwarazmita
Published: May 2023

Career research is still a topic that is not widely discussed, especially among undergraduates and alumni. Even though this still needs to be explored more deeply considering that a career is part of the responsibility of many parties in their selection. This study seeks to explore career choices by students by uniting family influence, personal interest, and economic conditions. The aim is to find out more clearly the variables that can influence the career choices of undergraduates at public and private universities. The population and samples respectively amounted to 970 and 95 respondents who could be used in the study. The use of sampling technique is using accidental sampling and the data is processed using SmartPLS 4.0. The findings were surprising in this study where family influence has an effect on career choice. On the other hand, personal interest and economic conditions have no effect on career choice.
Career Succes Perception, Is that Important?
Authors: Widayati Diana Titik , Malik Nazaruddin
Published: May 2023

This study proposes the factors that influence employees‘ career success in the manufacturing industry, the factors are mentoring, soft skills, and Self-efficacy. The research was carried out to examine employers’ opinions regarding the importance of mentoring, soft skills, and Self-efficacy in Batam. Data analysis use multiple regression and 100 respondent. Results show that Mentoring and Self-efficacy were not significantly related to career success. Only Soft skill (English, information technology, communication, and leadership) was significantly related to a successful career.
Propiedades psicométricas del Cuestionario Revisado de Bullying/Victimización de Olweus para Niños en español
Authors: Resett Santiago , Rodriguez Lucas M. , Moreno Jose Eduardo
Published: May 2023

El bullying es un importante factor de riesgo para la salud mental de niños y adolescentes, ya que las víctimas presentan mayores niveles de problemas emocionales; mientras que los acosadores muestran mayores problemas de conducta. A pesar de su relevancia, existen pocos instrumentos para su medición en niños de edad escolar. El presente estudio buscó evaluar las propiedades psicométricas del Cuestionario Revisado de Bullying/Victimización de Olweus en una muestra de habla hispana, con la particularidad de ser el primer análisis de habla hispana en niños. Se realizó un estudio instrumental, implementando AFE, AFC y correlaciones de Pearson. Una muestra intencional de 670 niños argentinos, varones (48 %) y mujeres (52 %), de 10 a 12 años (edad media = 10.80; DE = .72) contestaron el cuestionario, la Escala de Calidad de la Amistad y el Inventario de Depresión de Kovacs. Los resultados indicaron una estructura factorial de dos dimensiones: victimización y bullying, que coincidieron con las postuladas por el autor del cuestionario. Los valores de los coeficientes alfas de Cronbach y de omega de McDonald fueron satisfactorios. Se confirmó la evidencia de validez concurrente con la percepción de la calidad de la amistad y la depresión. El cuestionario presentó adecuadas propiedades psicométricas en su adaptación al español argentino.
Serum Antioxidant Status in Sickle Cell Disease Patients: Implications for Oxidative Stress and Disease Severity
Authors: Ali Hadi Zainab , Al-Tu’ma Fadhil Jawad , Hameid Odda Atheer , Almuhafdah Hawra
Published: May 2023

Objectives: The main aim of this subject is to determine the oxidative status of Iraqi sickle cell anemic patients and then correlated with various biomarkers.

Methods: In this study, blood samples from 100 sickle cell anemic subjects were analyzed, and then compared with control group which consisting of 50 individuals without sickle cell anemia was established. Various biochemical techniques were employed to measure different oxidative stress markers and inflammatory mediators. Serum samples were collected from blood to determine the levels of antioxidants such as catalase (CAT), glutathione peroxidase (G-Px), reduced glutathione (GSH), and lipid-peroxidation product malondialdehyde (MDA).

Results: The results revealed that the levels of serum antioxidant activity (CAT), GSH, and G-Px were significantly reduced with (P < 0.05) in sickle cell anemic patients as compared with apparently control group. In contrast, the MDA level was significantly higher in sickle cell anemic patients than that found in the apparently control group.

Conclusion: In this work, there is an increased oxidative stress in sickle cell anemic patients, which is accompanied by a decrease in antioxidant activity and a rise in lipid peroxidation, leading to the intensification of sickle cell anemic symptoms in patients.
Kerentanan Sosial pada Komunitas Pemulung di Perkotaan
Authors: Seruni Mayang Puti , Hidayat Rakhmat
Published: May 2023

The waste picker community faces social exclusion and poverty, resulting in a high degree of social vulnerability. To implement effective social policies, it is crucial to understand the complex social vulnerabilities experienced by these individuals. This study aims to illuminate the extent of deprivation faced by urban Indonesian waste pickers in the modern world, revealing not only the intricacies and depth of their vulnerabilities but also the contributing factors. A qualitative research approach was employed, consisting of interviews and observations within a South Tangerang waste picker community from 2014 to 2018. The findings reveal that waste pickers' vulnerabilities stem from interrelated, multidimensional, and layered deprivations. These vulnerabilities should not be viewed as isolated individual conditions but rather as collective community experiences. Consequently, social policies must be developed with a focus on the collectivity of waste pickers, taking into account their relationships and vulnerabilities, and implemented progressively over time.

AbstrakKomunitas pemulung hidup dalam eksklusi sosial dan kemiskinan, yang menyebabkan derajat kerentanan sosial mereka tinggi. Kebijakan sosial yang tepat tidak akan bisa terlaksana jika tidak diketahui kompleksitas kerentanan sosial yang dialami pemulung. Studi ini bertujuan untuk menjelaskan sejauh mana pemulung di perkotaan Indonesia mengalami deprivasi dalam dunia modern, sehingga dapat terungkap bukan hanya lapisan-lapisan dan kedalaman dari kerentanan mereka, tetapi juga beberapa faktor yang menjadi penyebabnya. Untuk itu, peneliti melakukan studi kualitatif dengan wawancara dan observasi pada satu komunitas pemulung di kota Tangerang Selatan, sejak tahun 2014 hingga 2018. Hasil temuan menunjukkan bahwa kerentanan yang dialami pemulung disebabkan oleh deprivasi yang berlapis, multidimensional dan saling berkaitan. Kerentanan pemulung juga tidak dapat dipahami sebagai kondisi individual, tapi pengalaman kolektif yang berbasis komunitas. Oleh sebab itu, kebijakan sosial yang dikembangkan harus memahami kolektivitas pemulung tersebut, harus menimbang semua relasi dan kerentanan yang dimiliki pemulung, dan harus dilaksanakan secara bertahap dalam waktu yang tidak sebentar.
CARACTERIZAÇÃO DE SOLOS PARA ANÁLISE DE RECALQUES: ESTUDO DE CASO
Authors: Almeida Bastos Joardes , Martins Cavalcante de Melo Fernanda , Khoiti Ueno Oscar , Gentil de Oliveira Almeida Vanessa , Alves de Oliveira Herbet
Published: May 2023

O recalque é um dos fenômenos que mais preocupa os engenheiros de fundações, sobretudo em solos argilosos. Para cálculo do recalque é necessário determinar o coeficiente de compressão e tensão de adensamento, cuja determinações são demoradas. Assim, o presente trabalho tem como objetivo avaliar a correlação entre as propriedades de solos do estado de Sergipe e seu respectivo recalque. Foram utilizados no trabalho três argilas do estado de Sergipe, Brasil. Os solos foram caracterizados pelos ensaios de composição granulométrica, índice de plasticidade, massa específica real, difratometria de raios-X (DRX), análise química por fluorescência de Raio-X  (FRX), teor de matéria orgânica e higroscopicidade. Foram produzidos corpos de prova cilíndricos, de 20 mm de diâmetro e 20 mm de altura, para a análise não saturada em prensa axial utilizando tensão de 30 MPa a 120 MPa, e corpos de prova com 100 mm de diâmetro e 10 mm de altura para a análise odométrica saturada. Os resultados apontaram que é possível estabelecer uma previsão do recalque de solos por meio do coeficiente de compressão, utilizando propriedades como composição granulométrica e índice de plasticidade.
In the Womb of Utopia: Feminist Science Fiction, Reproductive Technology, and the Future
Authors: Bonnevier Jenny
Published: May 2023

This article explores the ways in which reproductive technology is used as a literary trope to enable or embody adesired social order in a utopian setting. It discusses Ursula Le Guin’s The Left Hand of Darkness (1969) and “Coming of Age in Karhide” (1995), Joanna Russ’ The Female Man (1975), and Marge Piercy’s Woman on the Edge of Time (1976). In these American classics of feminist science fiction, reproduction is a key element, and they are rooted in a feminist understanding of power that sees the organization of both reproductive and child-care labor as central to analyses of patriarchy, as well as to any attempts to re-imagine patriarchal structures. The analysis draws on critical kinship studies that see the forming of kinship and families as a form of “cultural technology” and which thus opens these relationships to critical examination. It explores how the kind of change reproductive technologies can effect is not a property simply inherent in the technologiesthemselves. Rather, these medical technologies intersect with and become part of pre-existing cultural technologies of family and gender. Finally, the article addresses the question of how feminist futurities or feminist conceptions of time can be mobilized to enable resistance and change.
Do direito de moradia ao direito à moradia: perspectiva inclusiva da propriedade para concreção da dignidade da pessoa humana
Authors: Nunes Danilo Henrique , Netto Carlos Eduardo Montes , Lehfeld Neide Aparecida de Souza
Published: May 2023

A dignidade da pessoa humana, valor esculpido na Constituição de 1988 está diretamente relacionada aos aspectos envolvendo o direito à moradia como luta histórica pela inclusão e pela justiça social na sociedade brasileira. O presente artigo científico buscou abordar a perspectiva inclusiva do direito à moradia para promover a concreção do princípio da dignidade humana a consagrar os demais princípios civilistas e valores previstos no texto constitucional. Para tanto, a pesquisa se deu por meio dos métodos de revisão de literatura e método hipotético-dedutivo, buscando a identificação do tema, levantando problemas e hipóteses e representando suas implicações. Os resultados alcançados demonstraram claramente a incapacidade do Estado Brasileiro em resolver o déficit habitacional e demais problemas relacionados à questão da moradia, extrapolando da visão civil clássica do direito de propriedade, inviabilizando e perpetuando exclusão social e desigualdade em desfavor da camada mais pobre da sociedade. Portanto, é necessário empenho à luz do direito civil constitucionalizado na construção de políticas públicas que reflitam a perspectiva inclusiva da propriedade, gerando condições para que possa falar na concreção do acesso à moradia digna pela sociedade brasileira como um todo.
Una mirada a la trayectoria y los aportes científicos del arqueólogo Luis Hurtado de Mendoza
Authors: Peytrequín-Gómez Jeffrey
Published: May 2023

En el presente texto se discute los aportes fundamentales de la obra científica de un arqueólogo peruano, radicado en Costa Rica desde inicios de la década de 1980 y cuya carrera profesional se desplegó en este último país, haciendo grandes contribuciones al campo de esta disciplina: el Dr. Luis Hurtado de Mendoza. Para ello, se analizó la amplia literatura disponible del autor en cuanto a los tópicos abordados y sus alcances investigativos; a la vez, se recurrió a entrevistas para cotejar ciertos datos contextuales. Los resultados arrojan el despliegue de pilares temáticos cubiertos por este profesional, como la incursión en trabajos de índole transdisciplinar, el uso innovador de técnicas especializadas, el acercamiento multiescalar a distintos sitios arqueológicos, entre ellos Guayabo de Turrialba y el manejo de recursos (naturales y culturales) a escala regional. Sin olvidar su paso e impacto por la enseñanza en varios centros de educación superior a nivel nacional e internacional pero, de forma principal, en la Universidad de Costa Rica a principios de la década de 1980, integrando de manera formidable la investigación junto a la docencia y la acción social, así como su desempeño como arqueólogo destacado en el Instituto Costarricense de Electricidad en las dos primeras décadas del siglo XXI, estableciendo un modelo de gestión cultural ejemplar.
Rantai Pemasaran Usaha Ternak Sapi di Kabupaten Sigi (Study Kasus di SPR Anutapura Kabupaten Sigi)
Authors: Riandhana Taufiq Eka , Rahayu Ritha , Maksun Haerani , Syukur Suharno H. , Ashad M. , Indriani Indriani
Published: May 2023

Bentuk upaya pengembangan  ternak sapi, dipandang sangat tepat pada daerah di wilayah Sulawesi Tengah khususnya di Kabupaten Sigi, karena merupakan salah satu komoditi potensial daerah. Hal ini dimungkinkan, karena melihat potensi dan keadaan wilayahnya serta karateristik masyarakatnya sangat mendukung. Berdasarkan tinjauan aspek geografis, klimatologis dan sosial kultur masyarakat tersebut sangat potensial dan representatif untuk pengembangan ternnak sapi. Asumsi tersebut didasari oleh beberapa faktor yang merupakan kekuatan dan peluang yang dimiliki oleh Kecamatan Dolo Selatan Desa Bulu Bete. Penelitian dilaksanakan pada tanggal 3 April – 3 Juli 2022. Metode yang digunakan dalam penelitian ini adalah menggunakan metode observasi yaitu pengamatan langsung dan wawancara dengan anggota SPR Anutapura dan wawancara langsung dengan Ketua SPR Anutapura atau sekarang di sebut SASPRI (Solidaritas Alumni SPR Indonesia). Hasil penelitian menunjukan usaha ternak sapi di SASPRI menggunakan 3 pola saluran pemasaran yaitu : (1) Peternak → Konsumen, (2) Peternak → Pedagang Pengumpul → Konsumen, (3) Peternak → Pedagang Pengumpul → Pedagang Pengecer→Konsumen.
Pertumbuhan dan Hasil Tanaman Bawang Merah (Allium wakegi Araki) pada Berbagai Dosis Pupuk Kandang dan Konsentrasi MOL Daun Kelor
Authors: Tambing Yohanis , Andri Andri
Published: May 2023

Bawang Merah varietas Lembah Palu (Allium wageki Araki.) memiliki arti penting bagi masyarakat Kota Palu dengan ciri khas tekstur, rasa dan aroma yang khas sehinggga dewasa ini dikembangkan menjadi bahan baku industri bawang goreng khususnya di kawasan  kota Palu. Keberhasilan budidaya bawang goreng tersebut sangat tergantung kesuburan tanah sehingga diperlukan  pemupukan, khususnya pupuk organik sepeti pupuk kandang ayam dan pupuk mikro organisme lokal (MOL) daun kelor. Tujuan penelitian ini adalah untuk mengetahui pengaruh dosis pupuk kandang ayam dan konsentrasi MOL daun kelor yang tepat terhadap pertumbuhan dan hasil tanaman bawang merah varietas lembah Palu. Penelitian dilakukan dikebun akademik Fakultas Pertanian Universitas Tadulako dari bulan Desember 2021 sampai Februari 2022. Penelitian disusun menurut rancangan acak kelompok dengan perlakuan 2 faktor. Faktor pertama adalah dosis pupuk kandang ayam terdiri dari   kontrol,  3 kg/petak (15  ton/ha),  4 kg/petak  (20 ton/ha).  Faktor kedua adalah konsentrasi MOL daun kelor terdiri  dari  Kontrol,   200 ml/L atau  20%, 300 ml/L atau 30%, dan 400 ml/L atau 40%. Hasil penelitian menunjukan bahwa interaksi dosis pupuk kandang ayam dan konsentrasi MOL daun kelor tidak berpengaruh nyata pada semua parameter pengamatan, tetapi ada kecendrungan bahwa hasil umbi bawang merah per petak lebih tinggi pada perlakuan kombinasi dosis pupuk kandang 3 kg/petak (15 ton/ha) dengan  konsentrasi 300 ml/L MOL daun kelor dibandingkan kombinasi perlakuan lainnya.
Respon Pertumbuhan Setek Anggur (Vitis vinifera L.) Terhadap Pemberian Pupuk Kandang Sapi dan Pupuk Organik Cair
Authors: Sutopo Izma
Published: May 2023

Penelitian ini bertujuan untuk mengetahui respon setek tanaman anggur terhadap pemberian beberapa konsentrasi pupuk kandang sapi dan juga mengetahui respon pertumbuhan setek tanaman anggur terhadap pemberian beberapa kosentrasi pupuk organik cair herbafarm. Penelitian ini merupakan percobaan polibag dengan rancangan perlakuan factorial 3 x 3, disusun dalam rancangan acak lengkap (RAL) dan diulang sebanyak 3 kali.  Faktor pertama adalah pemberian pupuk kandang sapi (S) yang terdiri atas 3 macam yaitu: S1 = Pupuk kandang sapi 20 ton/ha-1 (50 gr/polibag), S2 = Pupuk kandang sapi 40 ton/ha-1 (100 gr/polibag), S3 = Pupuk kandang sapi 60 ton/ha-1 (150 gr/polibag).  Faktor kedua adalah pemberian pupuk organik cair Herbafarm (H) meliputi: H1 = Kosentrasi Herbafarm 5 ml/liter air, H2 = Konsentrasi Herbafarm 10 ml/liter air, H3 = Konsentrasi Herbafarm 15 ml/liter air.  Hasil penelitian menunjukkan bahwa pada kombinasi pemberian pupuk kandang sapi 20 ton/ha-1 (50 gr/polibag) dengan pemberian pupuk organic cair 5 ml/liter air (H1S1) memberikan hasil tertinggi pada panjang tunas.  Sedangkan pada analisis jumlah daun kombinasi pemberian pupuk kandang sapi 60 ton/ha-1 (150 gr/polibag) dengan pemberian pupuk organic cair herbafarm 15 ml/liter air (H3S3).
Inventarisasi Jenis-Jenis Rotan di Desa Balukang Kecamatan Sojol Kabupaten Donggala
Authors: Malik Adam
Published: May 2023

Rotan adalah tumbuhan palem berduri yang tumbuh berumpun atau tunggal yang tergolong dalam famili Arecaceae/Palmae. Secara ekologis, rotan tumbuh subur di berbagai tempat, baik dataran rendah maupun dataran tinggi, terutama di daerah lembah seperti bantaran sungai. Hampir semua bagian rotan dapat digunakan baik sebagai konstruksi kursi, pengikat, dan komponen desain. Penelitian ini dilakukan di Desa Balukan, Kecamatan Sojol, Kabupaten Donggala, Sulawesi Tengah. Penelitian ini dilakukan selama 2 bulan, mulai Juni 2020 hingga Agustus 2020. Berdasarkan hasil penelitian yang dilakukan di kawasan hutan Desa Baluang terdapat 7 spesies. Rotan Noko (Calamus koordersianus Becc), Rotan Lambang (Calamus Ornatus), Rotan Cabang (Korthalsia lariniosa Griffith ex Martius), Rotan Tohiti (Calamus inops), Rotan Batang (Calamus zollingeri Becc), Rotan Bubuai (Plectocomia elonganta Martius ex Blume), Rotan Ronti (Calamus leptostachys Becc).
Sektor Potensial yang Menunjang Perekonomian Kota Palu
Authors: Rappa Vera Yanti , Christoporus Christoporus , Rauf Rustam Abd.
Published: May 2023

Pertumbuhan ekonomi suatu daerah tidak terlepas dari peran sektor-sektor ekonomi yang ada di daerah tersebut. Salah satu sektor yang menjadi prioritas pembangunan adalah sektor pertanian. Hal ini karena sektor pertanian mempunyai peran secara langsung sebagai penyedia pangan masyarakat dan modal bagi pengembangan sektor lainnya. Tujuan penelitian ini untuk mengetahui sektor perekonomian yang berpotensi serta mengetahui sejauh mana sektor pertanian khususnya komoditi pangan di Kota Palu. Alat analisis data yang digunakan  dalam  penelitian ini adalah Analisis Tipologi Klassen, Analisis Deskiptif dan Analisis SWOT untuk melihat apakah sektor pertanian khususnya komoditi pangan masih dapat dipertahankan. Hasil penelitian menggunakan Analisis Tipologi Klassen menunjukan sektor transportasi dan pergudangan merupakan sektor maju dan tumbuh dengan pesat karena berada pada kuadran I. Adapun Sektor pertanian, kehutanan, dan perikanan, sektor pertambangan dan penggalian, serta sektor industri pengolahan merupakan sektor relative tertinggal. Hal yang menyebabkan sektor pertanian menjadi sektor relative tertinggal antara lain menurunnya luas panen, produksi dan produktivitas komoditi yang diakibatkan oleh permasalahan seperti konversi lahan pertanian, tingkat serangan hama/penyakit yang tinggi, sistem tata niaga yang belum tertata dengan baik dan bencana alam yang terjadi pada akhir tahun 2018. Namun meskipun demikian sektor pertanian (subsektor tanaman pangan, hortikultura, perkebunan dan perikanan) masih berpotensi untuk dikembangkan. Alternatif strategi untuk mempertahankan sektor pertanian khususnya komoditi pangan adalah (1) peningkatan produksi dan produktivitas pangan dan (2) penguatan kelembagaan bagi GAPOKTAN.
IDENTIFYING POTENTIAL PORPHYRY CU MINERALIZATION AT THE KIRAZLI DISTRICT IN BIGA PENINSULA (NW TURKEY): INSIGHTS FROM THE MAPPING HYDROTHERMAL ALTERATION BY USING SHORTWAVE INFRARED (SWIR) SPECTROMETRY
Authors: ALUÇ Ali , KUŞÇU İlkay , MORİTZ Robert
Published: May 2023

The Kirazlı mineral district is located at the center of the Biga peninsula metallogenic province, in a geological setting characterized by an extensional tectonic environment. The district hosts a high-sulfidation (HS) ore body with a total reserve of 33.86 Mt @ 0.69 g/t Au and 9.42 g/t Ag within a large-scale hydrothermal alteration. Although the ideal magmatic-hydrothermal models present the spatial and temporal association of HS-epithermal and porphyry Cu deposits, the porphyry Cu potential at the Kirazlı has not been evaluated, yet. Therefore, the mineral-based alteration mapping with the help of SWIR reflectance spectroscopy was carried out. Our study demonstrates that nine different mineral zone have been distinguished and mapped: (1) Silicification, (2) Alunite, (3) Kaolinite, (4) Dickite, (5) Illite, (6) Pyrophyllite, (7) Chlorite, (8) Sericite, and (9) Montmorillonite zones. Collectively, these alterations exhibit a zoned pattern, from central massive silicification to residual silica, NW-SE oriented alunite, and marginal montmorillonite-illite zones within widespread kaolinite – dickite dominated alteration in Kirazlı main zone. The occurrence of pyrophyllite and sericite dominates at the SE of the Kirazlı district, which refers to relative temperature increase. Subsequent drilling confirms the potential for deep prospecting of porphyry Cu mineralization in the region.