bluuebunny/crossref_metadata_2025 huggingface dataset:
Aerial Images Processing for Car Detection using Convolutional Neural Networks: Comparison between Faster R-CNN and YoloV3
Authors: Ammar Adel , Koubaa Anis , Ahmed Mohanned , Saad Abdulrahman
Published: October 2019

In this paper, we address the problem of car detection from aerial images using Convolutional Neural Networks (CNN). This problem presents additional challenges as compared to car (or any object) detection from ground images because features of vehicles from aerial images are more difficult to discern. To investigate this issue, we assess the performance of two state-of-the-art CNN algorithms, namely Faster R-CNN, which is the most popular region-based algorithm, and YOLOv3, which is known to be the fastest detection algorithm. We analyze two datasets with different characteristics to check the impact of various factors, such as UAV’s altitude, camera resolution, and object size. The objective of this work is to conduct a robust comparison between these two cutting-edge algorithms. By using a variety of metrics, we show that none of the two algorithms outperforms the other in all cases.
Konut Talebine göre Benzer Özellik Gösteren Türkiye İllerinin Panel Veri Kümeleme Analizi ile Belirlenmesi
Authors: AKAY Özlem , ÇELİK Cahit , KIRAL Gulsen
Published: October 2019

Bu çalışmanın temel
amacı uygun kümeleme yöntemi ile Türkiye’nin konut talebinde benzer özellik
gösteren illerini belirlemektir. Bu amaç doğrultusunda, 2008-2015 yılları
arasında Türkiye illerinin konut talebi ve konut talebini etkileyen ekonomik
faktörleri ele alınarak panel veri seti oluşturulmuştur. Ele alınan panel veri
setine, Öklid, Gower ve K-prototip uzaklıkları kullanılarak toplamsal
hiyerarşik kümeleme yöntemleri (Average, Complete, Ward, Single ve WPGMA) uygulanmıştır.
Kümeleme yöntemlerinin Cophenetic korelasyon katsayısı hesaplanarak uzaklıklar
için uygun kümeleme yöntemleri belirlenmiştir. Belirlenen kümeleme
yöntemlerinin küme geçerlilik (Dunn, Silhouette ve Connectivity) indeks
değerleri hesaplanmıştır. İndeks değerlerine göre, veri seti için Öklid
uzaklığı kullanılarak yapılan WPGMA kümeleme yönteminin uygun olduğu tespit
edilmiştir. WPGMA yönteminin kümeleme sonucuna göre Türkiye’nin konut talebinde
benzer özellik gösteren illeri belirlenmiştir.
Türkiye Hisse Senedi Piyasasında Spekülatif Balon Varlığının Ampirik İncelenmesi
Authors: ÇITAK Ferhat
Published: October 2019

Bu çalışmada, Türkiye pay piyasasında işlem gören 24 sektör ve gösterge endeksleri için, genelleştirilmiş eküs Augmented – Dickey – Fuller (GSADF) testi ile rasyonel spekülatif balonların varlığı analiz edilmiştir. İkinci aşamada, rasyonel spekülatif balonlarının görüldüğü tarihlere kukla değişken tanımlanarak balon oluşumunu etkileyen faktörler, logit modeli kullanılarak tespit edilmeye çalışılmıştır. Analiz sonuçlarına göre, Türkiye pay piyasasında  balon oluşma olasığını en fazla etkileyen değişkenlerin uluslararası portföy yatırımları (FPI), ülke kredi risk primi (CDS) ve uluslararası yatırımcıların risk algısı (VIX ) olduğu belirlenmiştir.
İş-Aile ve Aile-İş Çatışması, İş, Aile ve Hayat Tatmininin İşten Ayrılma Niyeti Üzerine Etkisi: Karşılıklı ve Demografik Değişkenli Etkileşimler
Authors: AKIN Özden , Karakulak Hüseyin
Published: October 2019

Yoğun ve hassas
görevleri olan hastane çalışanlarının iş ve aile sorumlulukları çatışma yaratmakta,
iş, aile ve hayat tatmini işten ayrılma niyetine yol açabilmektedir. Çalışmanın
amacı iş-aile çatışması, aile-iş çatışması, iş tatmini, aile tatmini, hayat
tatmini ve işten ayrılma niyeti ilişkisini ortaya koymaktır. Veriler anket tekniği yoluyla bir Üniversite hastanesindeki
hemşire, sağlık ve veri kayıt memurlarından toplanmış ve oluşturulan model
Yapısal Eşitlik Modeliyle test edilmiştir. İş-aile,
aile-iş çatışmasının işten ayrılma niyetine olumlu ve iş tatminine olumsuz etkisi
anlamlı çıkmıştır. Ayrıca değişkenler arası ilişkilerde
demografik değişken ve tatmin ve çatışma değişkenlerinin rolünün olup
olmadığına yönelik etkileşim analizleri yapılmış, anlamlı sonuçlar bulunmuştur.
Trabzon Bölgesel İnovasyon Sisteminin Firma İnovasyon Performansı Üzerindeki Etkisi
Authors: BADAY YILDIZ Ezgi , DİNDAROĞLU Yeşim
Published: October 2019

Günümüzde bir firmanın piyasada meydana gelen değişikliklere karşı olan duyarlılığı ve farklılaşabilmek adına gösterdiği inovasyon çabaları rekabet ortamında üstünlük sağlayabilmek adına en önemli unsurlar olarak görülmektedir. Söz konusu üstünlüğü elde etmek, firma inovasyon performansının arttırılmasından geçmektedir. Firma inovasyon performansını etkileyen en önemli unsurlardan biri ise firmanın içinde bulunduğu inovasyon sistemi olarak kabul edilmektedir. Bu bilgiler doğrultusunda, çalışmanın temel amacı Trabzon Bölgesel İnovasyon Sistemi’nin, Trabzon’da faaliyet gösteren firmaların inovasyon performansları üzerindeki etkisini incelemektir. Belirtilen amaç doğrultusunda Trabzon’da yerleşik 160 firmaya uygulanmış olan inovasyon anketi verisi yapısal eşitlik modellemesi kullanılarak incelenmiştir. Elde edilen bulgulara göre, kurumlarla yapılan işbirliği ve rekabet avantajı inovasyon performansını pozitif, ekosistemden kaynaklı engeller ise inovasyon performansını negatif yönde etkilemektedir.
Era Digitalisasi Media Pemasaran Online dalam Gugurnya Pasar Ritel Konvensional
Authors: Rohimah Afifatur
Published: October 2019

Digital communication era has impacts on the life, one of them is in the world of marketing communications. Based on data obtained, it was started in the end of 2016 to early 2017 that became the beginning of the turmoil of the modern retail market. One by one the modern retail market fell because modern society was not only to want comfortable shopping activities and places, but also practical and efficient. This was offered by online shopping, a lot of benefits coulbe be gains, such as making people prefer to online shopping activities rather than shopping conventionally. There were many benefits that offered by online shopping, the modern retail market should anticipate and implement several programs to maintain its existence in the market. It aims to make the life of the modern retail market more exist. In the era of the development of digitalization of communication needs alternative way to anticipate unexsistansion in society. So, that was no longer the process of fall of the conventional market in the digital era.
Aplikasi Elaboration Likelihood Model Theory dalam Iklan Calon Gubernur 2018 terhadap Perilaku Memilih
Authors: Norhabiba Fitri
Published: October 2019

The election of the head of the region would be held by government. It brought its own benefits to the campaign team. It was easy to find even before the pairing, the candidates who would forward to show his face in a billboard or banner on the sidewalk. Their poses for religious festivities or bright invokes blessings. They described in doing many positive activities to attract people's sympathy. Many governor candidates used outdoor media to advertise them in the governor election last June. Generally they showed self-advertising positively, memorable, and interesting. There were characteristics that highlighted. So, prospective voters would remember and did not hesitate to vote. This was the usual way of using elaboration likelihood theory either on peripheral routes or central routes. The central route involved critical thinking that peripheral routes did not do that. This theory was also associated with the behavior of people’s vote. The results of this conceptual study showed the finding that visible things are visually capable of capturing unselected voters with peripheral routes. In the other hand, voters who used the central route were given a lot of informative information to reinforce belief.
Pengaruh Mengakses Korean Wave terhadap Perilaku Imitasi Remaja di Kota Palu
Authors: Lathifah Isnaini Nurul , Herman Achmad , Yusaputra Muh. Isa
Published: October 2019

This study aims to determine the effects of Korean wave access activities that include: duration (X1), frequency (X2), attention (X3) to imitation behavior (Y) teenagers in Palu City. The researcher theory used Social Learning Theory. The study used survey method that used sample size from a population, with the number of samples were 73 students SMKN 1 Palu that represent few of teenagers in Palu City. This study used questionnaire as the main data collection tool and the method of analysis used multiple linear regression analysis. Based on the results of the coefficient of determination output (R2) obtained Adjust R Square (R2) in 0.740 or 74%. This result showed that the percentage was influence of X variable (duration, frequency, attention) in accessing Korean Wave through variable y (imitation behavior) teenagers in Palu that was 74%. Thus, the hypothesis Ha accepted and Ho rejected.
Influence of Transport Conditions on Optimal Injection Rate for Acid Jetting in Carbonate Reservoirs
Authors: Ridner Dmitry , Frick Taylor , Zhu Ding , Hill Alfred Daniel , Angeles Renzo , Vishnumolakala Narendra , Shuchart Chris
Published: October 2019

Acid jetting occurs as a result of pumping acid through limited-entry liner completions, causing high-velocity streams to impinge against the wellbore wall. The dissolution effect of jetting differs significantly from conventional matrix acidizing. Acid jetting causes cavities to be formed at the points of contact of the jet with the rock, with wormholes forming beyond the cavity. Jetting has been shown to be an effective technique for placing acid along extended-reach laterals, removing filter cake, and enhancing wormhole propagation.

The velocity of the impinging jet and its standoff distance from the rock cause some of the acid to penetrate the formation and some to flow back in the annular space of the liner. Two types of dissolution mechanisms occur: surface dissolution forming the cavity and matrix dissolution forming the wormholes. These dissolution mechanisms are highly dependent on the acid-injection rate, velocity of the jet, temperature, and permeability of the formation. The differences between the matrix dissolution mechanism of acid jetting and that of conventional matrix acidizing are most obvious at low acid-injection rates.

Experiments were performed with the intention of quantifying the difference in pore volume (PV) to breakthrough between acid jetting and matrix acidizing, as well as determining the effect of increased temperature, rock permeability, and acid concentration on this value with respect to the acid-injection rate. The baseline parameters of room temperature, 15% hydrochloric (HCl) acid, and 2- to 4-md Indiana limestone were individually compared with experiments run at 180°F, 28% HCl, and Indiana limestone cores of 30, 60, and 140 md. The effect of jetting velocity was also investigated. A direct comparison with conventional matrix acidizing was made by eliminating the jetting effect of the stream through mechanical dispersion.

Acid jetting creates a point of heightened interstitial velocity at the contact of the acid and the rock, causing wormhole propagation to occur at a faster rate than it would in conventional matrix acidizing at that injection rate. This effect is especially pronounced as the jetting velocity is increased above that of matrix acidizing, and it tapers off at progressively higher jetting velocities.
Comparison of the effects of intravenous and inhalational anesthesia on postoperative pulmonary complications after oral and maxillofacial surgery with free flap reconstruction: a double-blind, randomized, controlled trial
Authors: Zhou Dan , Zhu Xi , Wang Likuan , Yang Xudong , Liu Yun , zhang Xiang
Published: October 2019

Background: The effects of intravenous and inhalation anesthesia on intraoperative and postoperative pulmonary inflammatory responses have been reported in many studies. The differences in clinical postoperative pulmonary complications (PPCs) have been also studied in cardiac and lung resection surgery. However, there are few relevant reports and the findings remain controversial. Clinical evidence for the effects of these two anesthetics on PPCs in other types of surgery is still missing. The main goal of the current study was to assess the impact of sevoflurane and propofol on the incidence of PPCs in patients undergoing oral and maxillofacial surgery.

Methods: In this double-blind, randomized, controlled trial, we randomly assigned 220 adults at intermediate-to-high risk of pulmonary complications after oral and maxillofacial cancer surgery with radial forearm or fibular flap reconstruction to either propofol or sevoflurane as a general anesthetic. The occurrence of pulmonary complications according to the Clavien-Dindo score was defined as the primary (within 7 days after surgery) outcome.

Results: The two intervention groups had similar characteristics at baseline. The PPCs incidence during 7 days after surgery was 32.4% and 18.2% in the propofol and sevoflurane groups, respectively (adjusted relative risk, 0.44; 95% confidence interval [CI], 0.22 to 0.91; P = 0.027). The corresponding incidence of PPCs in patients who underwent tracheotomy at the end of surgery in the two groups was 44.8% and 24.5% (adjusted relative risk, 0.39; 95% CI, 0.17 to 0.91; P = 0.030). In addition, the Clavien-Dindo classification showed significant differences between groups in minor complications (grade I and II) but not in major complications (grade III to V). Intergroup difference in the time to occurrence of the first PPC after surgery was significant (P = 0.021). There was no difference in postoperative hospital stay between the two groups.

Conclusions: Compared with intravenous anesthesia, the administration of sevoflurane reduces the incidence of minor PPCs (grade I to II) in moderate- and high-risk patients who have undergone tracheotomy after oral and maxillofacial cancer surgery with radial forearm or fibular flap reconstruction.
Genomic and evolutionary features of two AHPND positive Vibrio parahaemolyticus strains isolated from shrimp (Penaeus monodon) of south-west Bangladesh
Authors: Ahmmed Shawon , Khan Md. Abdullah-Al-Kamran , Eshik Md. Mostavi Enan , Punom Nusrat Jahan , Islam Abul B.M.M.K. , Rahman Mohammad Shamsur
Published: October 2019

Background
Due to its rapid lethal effect in the early stage of shrimp, acute hepatopancreatic necrosis disease (AHPND) causing great economic losses, since its first outbreak in southeast China in 2009. Vibrio parahaemolyticus , carrying the pir A and pir B toxin genes is known to cause AHPND in shrimp. The overall objective of this study was to sequence the whole genome of AHPND positive V. parahaemolyticus strains isolated from shrimp ( Peneaus monodon ) of south-west region of Bangladesh in 2016 and 2017 and characterize the genomic features and emergence pattern of this marine pathogen.
Results
Two targeted AHPND positive V. parahaemolyticus strains were confirmed using PCR with 16S rRNA, ldh , AP3 and AP4 primers. The assembled genomes of strain MSR16 and MSR17 were comprised of a total of 5,393,740 bp and 5,241,592 bp, respectively. From annotation, several virulence genes involved in chemotaxis and motility, EPS type II secretion system, Type III secretion system-1 (T3SS-1) and its secreted effectors, thermolabile hemolysin were found in both strains. Importantly, the ~69 kb plasmid was identified in both MSR16 and MSR17 strains containing the two toxin genes pir A and pir B. Antibiotic resistance genes were predicted against β-lactam, fluoroquinolone, tetracycline and macrolide groups in both MSR16 and MSR17 strains.
Conclusions
The findings of this research may facilitate the tracking of pathogenic and/or antibiotic-resistant V. parahaemolyticus isolates between production sites, and the identification of candidate strains for the production of vaccines as an aid to control of this devastating disease. Also, the emergence pattern of this pathogen can be highlighted to determine the characteristic differences of other strains found all over the world.
Complete mitochondrial DNA sequence analysis of Bluespotted seabream, Pagrus caeruleostictus (Perciformes: Sparidae)
Authors: Afriyie Gyamfua , Guo Yusong , Kuebutornye Felix K.A , Larbi Christian Ayisi , Wang Zhongduo
Published: October 2019

Background Bluespotted seabream, Pagrus caeruleostictus is a benthopelagic marine species found in tropical regions and a member of the family Sparidae and genus Pagrus . In this article, a mitochondrial DNA sequence by high-throughput technique, Illumina Hiseq, was carried out on muscle of the above species and determined the complete mitogenome. Samples were obtained from species collected from the coast of Ghana, West Africa.Results The complete mitochondrial DNA sequence was 16,653 bases pairs in length (GenBank Accession number: MN319701) and comprises of 37 genes; 22 transfer RNA genes, 2 ribosomal RNA genes, 13 protein-coding genes as well as a control region as in a typical vertebrate mitochondrial DNA gene. The phylogenetic analysis showed P. caeruleostictus clustered with the clade of P. auriga. Conclusion This research will serve as the foundation for molecular genetic studies of Ghanaian fish species. Moreover, it will contribute to the phylogenetics of class Actinopterygii, order Spariformes, family Sparidae and genus Pagrus.
Effect of Resistance Training in the Treatment of Pre-Sarcopenia or Sarcopenia and Pre-Frailty or Frailty in Older People: A Systematic Review and Meta-Analysis of Randomized Controlled Studies
Authors: Talar Karolina , Vetrovsky Tomas , Kalamacka Ewa , Steffl Michal
Published: October 2019

Background: Resistance training (RT) is considered as an effective method to increase muscle strength and physical performance in elderly people. Methods: A search from the earliest record up to and including June 2019 was carried out using the following electronic databases: PubMed, Scopus and Web of Science. The search strategy employed combined the terms related to the population (e.g. ‘sarcopenia’, ‘frailty’) with terms for the intervention (e.g. ‘resistance training’, ‘strength training’). Results: 11 studies including 2691 subjects were included in our meta-analysis (aged 64-98). Training duration ranged from 8 to 48 weeks and intensity up to 80% of 1-RM. According to the meta-analyses, RT had statistically significant effect on all the measures except handgrip strength. In handgrip strength Effect size (ES) was 0.58 (95 % CI: - 0.10 to 1.26) p = 0.076 with the moderate heterogeneity (I 2 = 58.6%). ES in legs strength was 0.52 (95 % CI 0.11 to 0.92) p = 0.022, I 2 = 42.0 %. The biggest ES was in TUG test where ES was 0.90 (95 % CI 0.19 to 1.60) p = 0.022, however, there was a high heterogeneity I 2 = 89.6. The high ES was found also in FFM 0.69 (95 % CI 0.17 to 1.20) p = 0.025, and gait speed 0.41 (95 % CI 0.11 to 0.72) p = 0.017. In both cases, there was small heterogeneity I 2 = 13.2 % respective 38.3 %. The overall ES was estimated 0.67 (95 % CI 0.40 to 0.93) p <0.001. Nevertheless, the heterogeneity was high I 2 = 78.1 %.Conclusion: RT interventions in pre-frail, frail, pre-sarcopenic and sarcopenic older adults, provided evidence that RT has positive effects on most of the outcome measurements included in the current revision except handgrip strength.
Significance of Immune Checkpoint Inhibitors in Patients with Locally Advanced Non-Small Cell Lung Cancer Treated with Chemoradiotherapy Prior to the Approval of Durvalumab
Authors: Fukui Tomoya , Hosotani Shinji , Soda Itaru , Ozawa Takahiro , Kusuhara Seiichiro , Kakegawa Mikiko , Kasajima Masashi , Hiyoshi Yasuhiro , Igawa Satoshi , Yokoba Masanori , Mitsufuji Hisashi , Kubota Masaru , Katagiri Masato , Sasaki Jiichiro , Ishiyama Hiromichi , Naoki Katsuhiko
Published: October 2019

Background: The standard treatment for patients with unresectable locally advanced (LA) non-small cell lung cancer (NSCLC) was chemoradiotherapy (CRT). Consolidation therapy with durvalumab, an anti-programmed death ligand-1 antibody, after CRT demonstrated survival benefits and was approved in Japan in July 2018. The use of immune checkpoint inhibitors (ICIs) is entering routine oncological practice, and we investigate the feasibility of concurrent CRT for LA-NSCLC patients based on the PACIFIC criteria.Methods: We performed a retrospective study to evaluate the feasibility and efficacy of concurrent CRT prior to the approval of durvalumab. We assessed consecutive patients with LA-NSCLC treated with CRT between January 2012 and June 2018 in clinical practice, based on the PACIFIC criteria.Results: We analyzed a total of 108 consecutive patients ( 81 males and 27 females) who received radical thoracic radiotherapy and concurrent platinum-based chemotherapy. Of those, 105 patients (97%) completed the planned radiotherapy. Radiation pneumonitis was observed in 93 patients (85%), with a median of 130 days (range: 41–317 days) from the initiation of radiation to the onset of the complication. Among the patients, 74 (69%) were considered eligible for consolidation therapy with durvalumab. The overall response rate was 64%, and the 2-year survival rate was 63%. Of the 82 patients who relapsed after CRT, 18 patients received treatment with an ICI in the course of treatment. Patients who received an ICI after relapse were associated with significantly better survival than those who did not receive an ICI (2-year survival rate: 87% vs. 41%, respectively; p = 0.001).Conclusion: Prior to the approval of durvalumab, the clinical application of ICIs improved the outcome of patients with relapsed NSCLC after CRT for LA-NSCLC. The treatment strategy of ICI consolidation therapy for patients with LA-NSCLC and the management of radiation pneumonitis are challenges following the approval of durvalumab.
Efficacy and safety of dezocine in postoperative pain relief: Systematic review and Meta-analysis
Authors: Hao Fengxi , Fan Zhongyuan , Chen Feng , Yu Yongbo , Ren Yuanzhong , Yang Xuecheng , Wang Yonghua , Chu Haichen , Niu Haitao
Published: October 2019

Objective: To systematically evaluate the efficacy index and adverse reactions of dezocine in postoperative pain relief, provide statistical theoretical support for guiding clinical application.
Methods: We extracted and analyzed multiple data of patients from the PubMed, Embase, The Cochrane Library and China National Knowledge Infrastructure (CNKI) for use in randomized controlled trials of various surgical postoperative pain relief. We used meta-analysis to study several measures of efficacy and safety of dezocine, including visual analogue score (VAS), Ramsay sedation score, mean arterial pressure (MAP), heart rate (HR), Pulse Oxygen Saturation (SpO2) and the incidence of adverse events(AEs). The material data were calculated and analyzed using Review Manager 5.3.
Results: After exclusion of literature that did not meet the inclusion criteria, our analysis included 14 randomized controlled trials. The Mean Difference (MD) of VAS at 1 h/6 h/24h between the dezocine group and the placebo group was -1.37 (95% CI -2.07,-0.67, P=0.0001)，-0.52 (95% CI -1.04,0.01, P=0.05)，-0.10 (95% CI -0.39,0.20, P=0.52), respectively. The MD of Ramsay sedation score at 2h/8h was 1.21 (95% CI 0.67,1.75, P＜0.0001) and -0.17 (95% CI -0.59,0.26, P=0.44). The MD of MAP at T0/T1/T2 was -0.28 (95% CI -2.46,1.89, P=0.80)，-2.66 (95% CI -5.07,-0.25, P=0.03)，-4.53 (95% CI -6.17,-2.89, P＜0.00001). The MD of HR at T0/T1/T2 was -2.26(95% CI -4.32,-0.21, P=0.03)，-3.58(95% CI -5.21,-1.96, P＜0.0001),-3.75 (95% CI -11.55,4.04, P=0.35). The MD of SpO2 at T0/T1 was -0.90(95% CI -1.77,-0.03, P=0.04) and 0.36(95% CI 0.02,0.71, P=0.04).The odds ratio (OR) of AEs was 0.53(95% CI 0.39,0.71, P＜0.0001).
Conclusion: Dezocine shows appropriate anesthetic efficacy and fewer adverse effects, which can reduce postoperative pain effectively.
Comparative transcriptome analysis by Tilletia horrida infection in resistant and susceptible rice (Oryza sativa L.) male sterile lines reveals candidate genes and resistant mechanisms
Authors: Wang Aijun , Yin Desuo , Shu Xinyue , Wang Linxia , Li Ping , Zheng Aiping
Published: October 2019

Background Rice kernel smut (RKS), caused by the basidiomycete fungus Tilletia horrida , is one of the most devastating diseases affecting the production of male sterile lines of rice ( Oryza sativa ) worldwide. However, molecular mechanisms of resistance to T. horrida have not yet been explored.Results In the present study, analysis of the amount of T. horrida biomass in rice kernels and RNA sequencing (RNA-Seq) analysis of rice male sterile lines resistant and susceptible to RKS (Jiangcheng 3A and 9311A, respectively) were conducted after T. horrida infection. Transcriptomic analysis showed that 9, 840 and 7, 902 differentially expressed genes (DEGs) were observed in Jiangcheng3A and 9311A, respectively, after T. horrida inoculation, compared with the control. KEGG analyses of DEGs revealed that cutin, suberine and wax biosynthesis, flavonoid biosynthesis, glutathione metabolism, tyrosine metabolism, and biosynthesis of unsaturated fatty acids were enriched by T. horrida inoculation in Jiangcheng 3A; however, not significantly enriched in 9311A. Furthermore, the DEGs related to plant-pathogen interaction, plant hormone signal transduction, and transcriptional factor genes were identified in both rice male sterile lines.Conclusions This is the first comparative transcriptome analysis of two rice genotypes with different responses to T. horrida infection, revealing DEGs with potentially important roles in defense against T. horrida infection. Ours results will serve as a strong foundation for developing effective strategies for T. horrida -resistance breeding.
The changes of refractive status and anterior segment parameters after strabismus surgery
Authors: Zhou Wenke , Wu Hanyun , Zheng Yumeng , Zhang Li
Published: October 2019

Purpose To investigate the effects of strabismus surgery on the refractive status and anterior segment parameters, meanwhile to conduct a research on the causes of these changes. Methods This was a retrospective study about 65 patients (104 eyes) who underwent strabismus surgery by a single surgeon from February 2017 to May 2018. The patients were divided into 4 groups. Group I: unilateral lateral rectus recession (40 eyes), Group II: unilateral medial rectus recession (16 eyes), Group III: monocular lateral rectus recession and medial rectus resection (30 eyes), Group IV: disinsertion of the inferior oblique (18 eyes). Refractive status and anterior segment parameters were measured at 1 day before operation, 1 week, 1 month and at least 3 month after operation. Results Spherical equivalent significantly showed a myopic shift during postoperative 1 week in horizontal rectus surgery, and it still showed a statistical changes during postoperative at least 3 month unilateral medial rectus recession. J0 displayed a shift in the with-the-rule direction in unilateral medial / lateral rectus recession lasted to the at least 3 month after surgery. J45 had no significant change in all groups as time passed by. Patients manifested statistically significant changes in steepest keratometry at 1 week after operation in horizontal rectus surgery.Flattest keratometry changed significantly only in unilateral medial rectus recession lasted to the at least 3 month after surgery .There was no change in disinsertion of the inferior oblique . Conclusions Refractive changes are a significant side effect of strabismus surgery, therefore, patients should be informed about it prior to surgery and the appropriate time for optometry should be chosen according to the different surgical methods after surgery.
Palliative care quiz for nurses-Indonesian version (PCQN-I): A cross-cultural adaptation, validity, and reliability study
Authors: Herta Nuzul Sri , Wicaksana Anggi Lukman , Effendy Christantie , Kao Chi-Yin
Published: October 2019

Background The palliative care quiz for nurses (PCQN) has been frequently used to assess palliative care knowledge and has been adapted into several languages. The aim of this study was to perform a cross-cultural adaptation of the palliative care quiz for nurses into the Indonesian context (PCQN-I) and evaluate its psychometric properties.Methods A two-stage design was used in this study, including a cross-cultural adaptation and psychometric testing. The PCQN-I was tested on a convenience sample of healthcare providers recruited from 20 primary healthcare (PHC) centers in Yogyakarta, Indonesia, from July to October 2017.Results The cross-cultural adaptation ultimately resulted in a total of 20 items of the PCQN-I. An expert committee revised words in Item 4 “adjuvant therapies” to “adjuvant therapies/additional therapies”; Item 5 “bowel regimen” to “gastrointestinal therapies”; and Item 16 “Demerol” to “Pethidine” according to situation in Indonesia. The experts retained Item 5 “It is crucial for family members to remain at the bedside until death occurs,” although none of the participants (n = 40) involved in the pilot testing could answer it correctly; and Item 19 “The loss of a distant or contentious relationship is easier to resolve than the loss of one that is close or intimate”, although few participants responded correctly. A total of 150 healthcare providers consisting of 100 nurses and 50 physicians were involved in the psychometric testing. The scale-level content validity index/Ave of the PCQN-I was 0.97 and 0.93 in terms of its relevancy and clarity, respectively. The Kuder–Richardson formula 20 score was 0.71.Conclusions The PCQN-I is a valid and reliable instrument for assessing palliative care knowledge among PHC providers. Further research is warranted to examine its reliability in different clinical settings.
Survey of human and bovine tuberculosis infection on dairy farms in southwestern China
Authors: Zhang Shu , Chen Chuang , Rao Zhengyuan , Yang Aiguo , Guo Li , Hou Wei , Zhang Liang , Yang Xiulan , Liu Yan , Wu Yumei
Published: October 2019

Background Tuberculosis is a zoonotic chronic infectious disease that can be transmitted through respiratory secretions, causing simultaneous infection in both people and cattle. The aim of our study was to identify the co-infections of Mycobacterium tuberculosis between human and cattle in dairy farms in Sichuan Province, southwest China.Results We selected 6 large-scale dairy farms and 5 small-scale dairy farms in Sichuan Province, southwest China, as research sites. A total of 378 dairy farm workers (except one pregnant woman)were screened for tuberculosis symptoms and examined by X-ray radiographs. One worker was diagnosed with tuberculosis, but the sputum culture result was negative, and no strain was obtained. The purified protein derivative (PPD) skin tests of 10224 dairy cows showed that 99 cows were positive, with a positive rate of 9.7‰. The Oesophageal-Pharyngeal (OP) secretions of PPD-positive cows were cultured, and 21 strains were obtained. After amplifying and sequencing the 16SrDNA, hsp65 and rpoB genes and the ITS region, sequence alignment in BLAST showed that these strains were nontuberculous mycobacteria (NTM)(18 Mycobacterium nonchromogenicum , 1 Mycobacterium hiberniae , 1 Mycobacterium arupense and 1 Mycobacterium chitae ).Conclusion This study indicated that PPD-positive cows on dairy farms were infected with NTM rather than Mycobacterium bovis . Cross-infection of tuberculosis between humans and cows on dairy farms has been controlled.
Proteomic profiling of canine osteosarcoma patients
Authors: Jaroensong Tassanee , Roytrakul Sittiruk , Thitiyanaporn Chaiyakorn
Published: October 2019

Background Canine osteosarcoma (OSA) is an aggressive primary bone tumor in dogs. Metastasis of canine OSA occurs mainly in the lungs through the hematogenous route. Identification of the proteins that are associated with metastasis using proteomic technologies is important not only for the discovery of OSA targets and signaling pathways associated with metastatic OSA but also to provide novel therapeutic targets. The objective of this study was to conduct a proteomic profiling analysis of canine OSA patients. We used mass spectrometry to examine the protein profiles.Results We found the overexpression of five proteins from OSA tissues—myosin (MYO7a), GTPase IMAP family member 5 isoform 1 (GIMAP5), PR domain 15 (PRDM15), A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4), and interleukin receptor type 1 (IL1R1)—and one protein from the serum, rCG38920.Conclusions In this study, we identified numerous proteins in the tissue and serum of patients with malignant and benign OSA or non-OSA through a proteomic approach using mass spectrometry. These proteins may be useful for diagnosis and prognosis, including the prevention of misdiagnosis between malignant OSA and non-OSA as these have similar clinical symptoms in the early stages. In the future, further independent validation of these biomarkers using a greater number of patient samples and different techniques, including Western blot, is necessary to improve diagnostic power for differentiating malignant OSA patients from non-OSA patients.
Resting energy expenditure guided intervention for gestational weight gain in obese and overweight women
Authors: Zhao Xiuling , Ma Wei , Zhang Caixia , Xu Pili , Zhang Chunmei , Jiang Shan , Gaudet Laura , Gao Jie , Wen Shi Wu
Published: October 2019

Background There is sparse in the literature on resting energy expenditure guided intervention to manage gestational weight gain in obese and overweight women.Methods We conducted a prospective cohort study in Beijing, China between May 1, 2017 and April 30, 2018. Obese/overweight women who visited the Department of Obstetrics and Gynecology at LuHe hospital of Capital Medical University, a tertiary care facility in Beijing, China, for their routine prenatal care at 10-13 weeks of gestation during the study period were recruited into the study after written consent was obtained. Women whose pre-pregnant body mass index was < 25Kg/m2 or who took steroid medication or those diagnosed with thyroid disease or affected by pre-pregnant diabetes mellitus or for other reasons could not participate in the study assessments were excluded. Participants who were recruited between May 1, 2017 and December 30, 2017 were the designated control group with diet recommendation based on pre-pregnancy body mass index and ideal weight, without resting energy expenditure monitoring. Those who were recruited between November 1, 2017 and April 30, 2018 were the intervention group, with resting energy expenditure guided diet recommendation to manage gestational weight gain. Gestational weight gain and perinatal outcomes between the two study groups were then compared.Results A total of 53 eligible women (32 in intervention group and 21 in control group) were recruited and included in the final analysis. There was no difference in baseline demographic and clinical characteristics between the two groups. Gestational weight gain in the intervention group (13.45±4.16 Kg) was lower than in the control group (18.20±4.84 Kg). Rate of macrosomia in the intervention group (3.12%) was also lower than in the control group (19.05%). There was no fetal growth restriction observed in either group.
"It Is Just That We Are Alive But We Are Suffering" Experience Of Food Insecurity Among Elderly In Morogoro-tanzania
Authors: KILUME UPENDO , NYAMHANGA TUMAINI
Published: October 2019

Background Studies on food insecurity in Tanzania have been quantitative in nature and have focused on specific population groups such as those of people living with HIV and women. However, there is very little, if any, qualitative research information in Tanzania on experiences of food insecurity among elderly with respect to its magnitude and associated circumstances.Methods Interview guide and focused group discussion guide were used to explore the magnitude of food insecurity among elderly and its associated circumstances. A total of 25 elderly and 3 district officials were involved in in-depth interview and another 25 elderly were involved in focused group discussion.Results The study found that elderly had limited access to food, eat less number of meals as well as insufficient amount. The circumstance associated with food insecurity were found to be limited strength to engage themselves in farm activities or working as casual laborers to earn some money to buy food, limited strength to prepare food, burden of taking care of grandchildren and inadequate food support from children.Conclusion In conclusion, this study has demonstrated that the elderly people experience food insecurity with respect to both quantity and quality. Therefore, it is high time that a strategy was developed to ensure that all elderly in Tanzania are food secure.
Quantifying and interpreting nestedness of bryophytes in the Zhoushan Archipelago, China
Authors: Yu Jing , Li Dandan , Shen Lin , Zhuo Busheng , Guo Shuiliang
Published: October 2019

Background: Detecting nestedness distribution and understanding their origin are important for biological conservation. Although previous studies on nestedness covered a wide range of taxa, discrepancies still exist on the prevalence of nestedness among biotas, and on the mechanisms to form nested distribution. Because bryophytes are poikilohydric, highly sensitive to habitats, and have a long-distance dispersal capacity, together with the fact that continental islands highly varied in area, elevation and habitat types, bryophytes on continental archipelago are thus an ideal system for the settlement of relevant disputes on nested distribution. However, few studies have been conducted on nestedness of bryophytes. To quantify nestedness level of different bryophyte categories on continental islands and possible mechanisms, we complied a presence/absence matrix of 446 species of bryophytes in 66 islands of the Zhoushan Archipelago, China. We also recorded spore sizes of 319 moss species based on available literature. By using the matrix temperature and the NODF metrics, as well as a conservative null model, we evaluated the nestedness levels of 18 bryophyte categories. We further explored possible mechanisms to form nested distribution by using partial Spearman rank correlations based on island area, elevation, habitat types and spore size of moss species.
Results : We found that all 18 categories of bryophytes exhibited a high degree of nestedness. Nestedness level was higher for mosses than liverworts, higher for acrocarpous mosses than pleurocarpous mosses，and varied among different bryophyte 13 families. The nested distribution of bryophytes in the archipelago was not due to passive sampling, but mainly due to nested habitats and selective-extinction. Spore size might be a factor linked to selective-colonization accounting for nestedness of some moss categories.
Conclusions : Nested habitats, selective-extinction, and partial selective-colonization resulted in a high level of nestedness for bryophytes in continental islands. Although the nestedness of bryophyte distribution in the Zhoushan Archipelago was statistically significant, such a nestedness was not perfect. Conservation of bryophytes should not only focus on the species-richest islands.
Survival Benefits and Safety Profile of T ransarterial C hemoembolization (TACE) B ased Monotherapy or Multi-modal Therapies in Locally Advanced Stage Hepatocellular Carcinoma: an Observational Study from Real-World Setting
Authors: Yin Xin , Tang Bei , Zhang Feng , Hu Keshu , Yuan Jia , Li Miao , Lu Shenxin , Wang Yanhong , Chen Rongxin , Zhang Lan , Zhang Boheng , Ren Zhenggang
Published: October 2019

Background : Majority of patients with locally advanced hepatocellular carcinoma (HCC) in Asian-Pacific regions underwent transarterial chemoembolization (TACE) or TACE-based muti-modal treatments instead of molecular target therapy in clinical practice. We aimed to evaluate the treatment outcomes and safety of transarterial chemoembolization based multi-modal treatments in locally advanced HCC from a real-world setting. Methods: From January 2008 to December 2015, 552 patients with locally advanced HCC who received TACE based monotherapy or multi-modal treatments at Liver Cancer Institute, Zhongshan Hospital, Fudan University were retrospectively enrolled. The clinical outcome of these patients were evaluated among these treatment groups. Propensity score matching analysis was performed to reduce potential bias for comparing treatment modalities. Results: Of all the patients, 375 patients received TACE treatment, 83 patients received TACE followed Sorafenib treatment (TACE+Sorafenib), 30 patients received TACE followed local ablation treatment (TACE+LAT), and 64 patients received TACE followed radiotherapy (TACE+Radiotherapy). 1-, 3-, 5-year OS rates in TACE group were 50.5%, 29.8% and 24.5% vs. 74.3%, 46.6% and 37.6% in TACE+multi-modal treatment group (P<0.001). The median survival time was 7.5 months, 13.0 months, 16.5 months, 10.0 months for TACE alone group, TACE+Sorafenib group, TACE+LAT group, and TACE+Radiotherapy group respectively. After propensity score matching, survival benefits were verified in TACE+Sorafenib and TACE+LAT treatments group. Safety analysis showed the major adverse events rates was 3.6% in TACE alone group and 3.9% in TACE+multi-modal treatment group with no statistic difference (P=1.0). Conclusions: TACE+Sorafenib treatment or TACE+local ablation treatment could achieve superior survival benefits to TACE alone in the management of locally advanced HCC.
The Uniform Prior for Bayesian Estimation of Ability in Item Response Theory Models
Authors: Karadavut Tuğba
Published: October 2019

Item
Response Theory (IRT) models traditionally assume a normal distribution for
ability. Although normality is often a reasonable assumption for ability, it is
rarely met for observed scores in educational and psychological measurement.
Assumptions regarding ability distribution were previously shown to have an
effect on IRT parameter estimation. In this study, the normal and uniform
distribution prior assumptions for ability were compared for IRT parameter
estimation when the actual distribution was either normal or uniform. A
simulation study that included a short test with a small sample size and a long
test with a large sample size was conducted for this purpose. The results
suggested using a uniform distribution prior for ability to achieve more accurate
estimates of the ability parameter in the 2PL and 3PL models when the true
distribution of ability is not known. For the Rasch model, an explicit pattern
that could be used to obtain more accurate item parameter estimates was not
found.
Teologi Guanxi: Sebuah Upaya Memahami Aspek Teologi Relasional dalam Budaya Tionghoa
Authors: Baito Linus
Published: October 2019

This article aims at constructing a theology of business starting from the Chinese principle of relationship which is known as guanxi. Many have seen the role of guanxi in the process of China’s economic growth. Guanxi plays a philosophical role not only in economic life, but also in social as well as cultural ones. Using Robert Schreiter’s method of intercultural theology, this study finds that the philosophical concept of guanxi offers values compatible with a Christian theology of relationship. Interacting the two resources would provide a strong basis for constructing a theology of business.
Resensi Buku Relasionalitas, Filsafat Fondasi Interpretasi: Aku, Teks, Liyan, Fenomenon
Authors: Hutabarat Haleluya Timbo
Published: October 2019

Buku yang ditulis Armada Riyanto ini menggunakan filsafat fenomenologis dalam memaknai dan memahami relasi antara 'Aku, teks, liyan, fenomen'. Cara kerja dan hasilnya, bisa dilihat dalam framework hermeneutika teks, tetapi juga studi intersubjektifitas lainnya seperti riset fenomenologis, sosiologi interpretatif, studi indentitas, penelitian sumber daya manusia, teori pendidikan, dan sosio-politis-kultural-religius kearifan lokal. Buku yang terdiri dari 10 babini memiliki banyak manfaat dan menjawab kebutuhan akademis sekaligus tantangan kemanusiaan jaman sekarang.
Constraining new physics from Higgs measurements with Lilith: update to LHC Run 2 results
Authors: Kraml Sabine , Quang Loc Tran , Nhung Dao Thi , Ninh Le Duc
Published: October 2019

Lilith is a public Python library for constraining new physics from
Higgs signal strength measurements. We here present version 2.0 of
Lilith together with an updated XML database which includes the current
ATLAS and CMS Run 2 Higgs results for
36 fb^{-1}−1.
Both the code and the database were extended from the ordinary Gaussian
approximation employed in Lilith-1.1 to using variable Gaussian and
Poisson likelihoods. Moreover, Lilith can now make use of correlation
matrices of arbitrary dimension. We provide detailed validations of the
implemented experimental results as well as a status of global fits for
reduced Higgs couplings, Two-Higgs-doublet models of Type I and Type II,
and invisible Higgs decays. Lilith-2.0 is available on GitHub and ready
to be used to constrain a wide class of new physics scenarios.
Research on vibration displacement test method for large-caliber artillery muzzle
Authors: Li Shili , Chao Hongxiao , Wang Dongying , Ren Junlong
Published: October 2019

In order to solve the problem of muzzle vibration displacement test of large caliber under high elevation, this paper presents a test method by two high-speed photography. The method fully considers the influence of the muzzle torsion on the measurement results, and accurately obtains the three-dimensional vibration displacement of the muzzle of the large caliber artillery. Finally, through the result analysis, the accuracy of the measurement results can reach 0.1 mm, which shows the advantage of the sub-pixel-based high-speed camera processing method in the muzzle vibration displacement test of the conventional artillery. This paper proposes an innovative test method that accurately measures the vibration displacement of the muzzle using a non-contact method.
Predictions of input pinion floating on concentric face gear transmission static load sharing
Authors: Li Si , Li Zhengminqing , Tang Xin , Zhu Wenlin , Liao Meijun
Published: October 2019

A static load sharing analysis model of concentric face gear transmission associated with the input pinion floating is constructed, and the calculation method of static load sharing is proposed. The influence of the input pinion floating on static load sharing is predicted. The results show the input pinion floating stiffness reduction could benefit for the concentric face gear transmission static load sharing.
On-site vibration test and dynamic response analysis of wind turbine of intertidal zone
Authors: Huang Shuai , Lyu Yuejun , Peng Yanju , Sha Haijun
Published: October 2019

In our study, the vibration signal of impulse response and attenuation response are extracted using the correlation function and power spectrum, and the natural frequency of wind turbine is determined. Compared with the rotation frequency of the blades of wind turbine which are 1p (one blade) and 3p (three blades), and wind vibration performance of the wind turbine is determined. The natural frequency of wind turbine is between the frequencies of one blade and three blades of wind turbine, which can avoid resonance phenomenon and meet the precision requirement for engineering application. The laws of acceleration and strain response along the wind turbine under ordinary wind load are obtained by installing acceleration sensor and strain gauge along the wind turbine. We found that the acceleration at the wind turbine top increases 10 times than that at the bottom. The acceleration influenced by tide is 1.14 times than that with no tide. The strain produced maximum value at the opening place of wind turbine and near the top, it should be paid attention in the engineering design.