bluuebunny/crossref_metadata_2025 huggingface dataset:
Mobilisation précoce des patients admis en réanimation pour hémorragie sous arachnoïdienne
Authors: Foudhaili Adela , Chousterman Benjamin , Houzé Marie-Hélène , Vitiello Damien
Published: April 2023

L’hémorragie sous-arachnoïdienne (HSA) représente environ 5% des accidents vasculaires cérébraux, et touche une population jeune. Les patients atteints d’HSA sont hospitalisés plusieurs semaines afin de traiter l’anévrisme et de surveiller l’apparition d’éventuelles complications. Il n’y a pas à ce jour de recommandations sur la mobilisation de ces patients et les pratiques sont hétérogènes. Les patients sont généralement alités pendant les deux à trois premières semaines qui suivent l’HSA, dans le but de ne pas induire de variations hémodynamiques potentiellement délétères. Il n’y a cependant pas de preuves que cela soit nécessaire et l’alitement prolongé est susceptible d’entraîner de multiples complications. La littérature existante, bien que peu abondante, a montré que dès les premiers jours suivant l’HSA, la mise en place de protocoles de mobilisation précoce progressive conditionnée par une évaluation clinique rigoureuse et encadrée par des critères de surveillance est possible, sécuritaire et potentiellement bénéfique pour les patients atteints d’HSA.
Singapore Convention and Russian laws: Requirements towards International Commercial Settlement Agreement Resulting from Mediation
Authors:   Russian Foreign Trade Academy with the Ministry of Economic Development of Russia, Gaidaenko Schaer Natalia I.
Published: April 2023

Once Singapore Convention on Mediation was adopted in 2018 and it has become possible to facilitate performance of the international commercial settlement agreements resulting from mediation abroad interest to mediation as a means of settlement of the international commercial disputes started to grow. In the eyes of the lawyers such mediated settlement agreements have much in common with the awards of international commercial arbitration, the most popular dispute resolution tool for disputes arising during foreign trade activities. Today in the age of turbulence and chaos mediated settlement agreements allow to satisfy the needs of business in the expediate settlement of foreign trade conflicts on the terms acceptable for the parties and to obtain guarantee of quick, simple and cost-efficient performance of the agreements reached. For this reason, it is worth considering adjustment of the internal laws to the best world practices. Article considers the means available under the Russian laws to make mediated settlement agreement enforceable and the tests it would have to undergo on the way. Deeming it advisable for Russia to join the Singapore convention on mediation, author concludes that it is necessary to prepare the internal legislation for such step as it was done, e.g., in Belorussia. Possible solution could consist either in introduction of a special chapter on granting relief in connection with the performance of international commercial mediated settlement agreements corresponding to the provisions of the Singapore Convention on mediation and the UNICTRAL Model law on mediation in the Russian Code of Procedure with Commercial Courts or in the adoption of a separate law on international commercial mediation. Since international commercial arbitration and the internal arbitration are regulated in Russia by two separate laws taking into account the special features of the disputes resolved, it would be logic to keep dualistic regulation for mediation as well.
Kimonro cha Mvuli asahau uume wake nrowa ni jamaa kinavowasilishwa katika Utendi wa Ramani ya Maisha ya Ndoa (Mume): Uchanganuzi Kifano
Authors: Karama Mohameḍ
Published: April 2023

Katika ṭaaluma ya fasihi ya kiSwahili uṭeṇḍi maarufu uliyoṭafiṭiwa mno kuhusu masiyala ya nrowa, kazi na majukumu ya mke k̇a mumewe, ni ule wa Ṁanakupona. K̇a mara ya k̇anza, makala haya yanaangaziya uṭeṇḍi ṁengine ambao haujaṭafiṭiwa k̇a ṭafsili wenye kuraṭibu kazi na majukumu ya mume k̇a mkewe. Utendi wa Ramani ya Maisha ya Ndoa (Mume) uliyotungwa na Usṭadh Mahmouḍ Mau unampa mvulana wasiya wa kutumiya katika kufaulisha nrowa yake. Makala haya yaṇjaribu kudhihirisha elimu ya kiḍini na hekima ya ṭajiriba ya kimaisha aliyonayo mtunzi k̇a kumnasihi mvuli kuwa hakuna ukʰuu katika nrowa. Makala haya yakiongozwa na nadhariya ya Usemezano yamechanganuwa maudhui ya hekima ya mtunzi na kubainisha kuwa: k̇enye mukṭadha wa nrowa mke na mume wanasemezana si wao peke yao bali na jamii k̇a ujumla; kuna mabaḍiliko ya maana ya maneno kila kukicha basi na maana ya uume piya inabaḍilika kila kukicha; na ṁishowe, maana inayokuja baaḍa ya kukaa nrani ya maisha ya nrowa huwa ṭafauṭi na ile ilozoweleka. Makala haya yanahiṭimisha kuwa mtunzi aliṭaka kumfunza mvulana na msichana kuwa maisha ya nrowa ni ya watʰu wawili lakini majukumu zaiḍi yanaṁangukiya mume katika kufaulisha nrowa yake. Isiṭoshe, uṭeṇḍi huu unamkazaniya mume amsome mkewe kila siku kila saa ili aweze k̇idhibiṭi nrowa. Naṭija ilopatikana k̇a kuushughulikiya uṭeṇḍi huu ni kubaḍilisha nadhari katika ṭaaluma za kiSwahili na kijinsiya k̇a k̇angaziwa sana Ṁanakupona na kuṭoṭafiṭiwa ṭʰeṇḍi nyenginezo haswa zinazotiliya maanani mtoto wa kiyume.
Cyber Security and Data Collection
Authors: Milenković Dejan Z.
Published: April 2023

Every country that seeks to protect its national interests and security in the information age faces the problem of adequately protecting the national information sphere. As a confirmation of this thesis, modern security studies talk about cybersecurity and its importance for national security. Therefore, we can say that cybersecurity protects the vital interests of individuals, society and the state in the information sphere from external and internal dangers and risks. The main threat in the sphere of international cybersecurity is the use of information and communication technology as an information weapon for the achievement of political and military goals that conflict with international law, for violating public order, inciting inter-ethnic, inter-religious and inter-denominational hatred, as well as for carrying out criminal and intelligence - subversive activities. The paper's subject is a comprehensive overview of cyber security and its impact on national security.
The non-unitary nature of information preference
Authors: Liew Shi Xian , Embrey Jake R. , Newell Ben R.
Published: April 2023

Factors affecting information-seeking behaviour can be task-endogenous (e.g., probability of winning a gamble), or task-exogenous (e.g., personality trait measures). Various task-endogenous factors affecting non-instrumental information-seeking behaviour have been identified, but it is unclear how task-exogenous factors affect such behaviour, and if they interact with task-endogenous factors. In an online information seeking experiment (N = 279), we focus on the role that outcome probability, as a task-endogenous factor, has on information preferences. We find reliable preference for advance information on highly probable gains and low preference for highly probable losses. Comparisons with individual trait measures of information preference (e.g., intolerance of uncertainty scale, obsessive-compulsive inventory, information preferences scale) reveal minimal association between these task-exogenous factors with choice task performance. We also find minimal interaction between outcome probability and individual trait measures. Despite the choice task and trait measures purportedly tapping the same (or similar) construct, the absence of clear relationships ultimately suggests a multi-dimensional nature of information preference.
Indium-mediated Domino Lactonisation Approach towards Diastereoselective Synthesis of Pyrazole C-3 Linked Butyrolactones
Authors: Sharma Dr Shubham , Singh Dr Virender , Singh Dr Manpreet , Sharma Dr Ashutosh
Published: April 2023

A facile tandem approach has been established for the convenient diastereoselective synthesis of novel pyrazole and α-methylene-γ-butyrolactone based molecular hybrids. Indium-mediated Barbier-type allylation reaction was performed followed by in situ lactonisation approach. No additive was needed for this transformation and the butyrolactone derivatives were obtained with syn stereochemistry in good yields. The current protocol offers several advantages such as one-pot procedure, high diastereoselectivity, broad substrate scope and good yields of the desired products.
CLIMATE CHANGE IN INDIA: ISSUES AND CHALLENGES
Authors: Singh Samsher , Jose Dr. Kishor
Published: April 2023

The Intergovernmental Panel on Climate Change’s (IPCC) described climate change as long-term changes in temperature, humidity, clouds, and rainfall and not to routine variations (IPCC 2007). Inevitably, Climate change is the matter of critical concern that is faced by today’s humanity. Climate change is the very significant challenge that have an effect on the very survival of life on earth and has implications for food, water, biodiversity, energy, and health etc. The environment and sectors related to socio-economic conditions of the country, which consist of resources that are associated with water, agriculture production and food security, biodiversity and another related sector are comprehensively affected by the climate change. It also results in changing pattern of rainfall, and these changes in rainfall give rise to the problem of stringent water shortage or flooding. It also causes a rapid increase in mean temperature, which gives pace to the rate of melting of glaciers further leading to flooding, the rise in sea level and soil erosion. Increasing temperature also causes an alteration of the season for crops production which in turn affects food security. The following paper addresses the term ‘climate change.’ And the challenged posed by the climate change for India. Being a developing country, India is extremely susceptible to the consequences of climate change because it could impede its economic progress. This paper is descriptive in nature and to be accomplished by using historical analytical method.
A COMPARATIVE STUDY BETWEEN THE OLD INCOME TAX AND THE NEW TAX REGIME ON INDIAN INDIVIDUAL TAX PAYERS
Authors: Rabidas Dr. Shiv Kumar
Published: April 2023

The Indian government has announced a new tax slab in the Union Budget for 2020–21. The government did not abolish the previous tax system; this new tax slab is sometimes referred to as an optional tax regime. The option for the taxpayer is to select the tax regime—either the old or the new. Compared to the previous tax structure, the new tax regime features a lower tax bracket. The option for the taxpayer is to select either the new tax structure with lower tax slabs or the previous tax structure with higher tax slabs but tax benefits. The previous tax system allowed taxpayers to make use of existing tax breaks such as the house rent allowance, leave travel allowance, and other deductions allowed by the Income Tax Act of 1961. The advantages of the current exemptions and deductions that are offered under the old tax regime will not be available to individuals who choose the new tax regime. The new tax system has a lower tax rate and six tax slabs, compared to the old tax system's higher tax rate and three tax slabs. In both tax regimes, the tax rate for individual under 60 is comparable because they are exempt up to 2.5 lakh. Additionally, individuals who are residents of India for income tax purposes are eligible to claim a tax rebate of up to Rs. 12,500 against their tax liabilities under Section 87A, provided taxable income does not exceed Rs. 5, 00,000.
EXPLORING NAUTICAL CULTURE IN GUNVANTRAI P ACHARYA’S DARIYALAL: A STUDY
Authors: Soni Rima B , Rao Dr. Vidya G
Published: April 2023

Nautical culture with its various characteristics has attracted writers over the years. Gunvantrai Popatbhai Acharya, who is exceptional in Gujarati language and literature, is one of the leading discoverers of audacious nautical narratives in Gujarati literature. Ancient accomplishments of Gujarati shipment are portrayed in Acharya’s Dariyalal written in the Gujarati language in the foundation stage. Subsequently, the text was translated into English by Kamal Sanyal and demonstrated by Gautam Chattopadhyay in 2000.The focus of the novel offered is set against the background of past experience. The present paper titled, “Exploring Nautical Culture in Gunvantrai P Acharya’s Dariyalal: A Study” seems to explore nautical fantasy, importance of sea, festivities related to sea and Guajarati oceangoing community with the kaleidoscopic aspects.
Pengaruh Sarana Kerja, Kepemimpinan dan Dukungan Manajemen terhadap Kinerja Pegawai Melalui Motivasi Kerja sebagai Variabel Mediasi (Literature Review Manajemen Sumber Daya Manusia)
Authors: Haryati Djonu Janny , E. H. J. FoEh John , Man Stanis
Published: April 2023

Abstract: This article will focus on analyzing the influence of work facilities, leadership, management support, and work motivation on employee performance. The results of the literature review obtained: 1) Work facilities have a significant effect on employee performance; 2) Leadership has a significant impact on employee performance; 3) Management support has a significant impact on employee performance; 4) Motivation has a significant effect on employee performance; 5) Work facilities have a significant effect on performance with work motivation as a mediating variable; 6) Leadership has a significant effect on performance with work motivation as a mediating variable; 7) Management support has an important influence on performance with work motivation being the mediating variable; 8) Work motivation mediates the influence of work facilities, leadership and management support on employee performance.
Abstrak: Dalam artikel ini akan focus ke analisis pengaruh sarana kerja, kepemimpinan, dukungan manajemen maupun motivasi kerja kepada kinerja karyawan. Hasil kajian pustaka memperoleh: 1) Sarana kerja memengaruhi signifikan bagi kinerja karyawan; 2) Kepemimpinan memengaruhi signifikan bagi kinerja pegawai; 3) Dukungan manajemen memengaruhi signifikan bagi kinerja karyawan; 4) Motivasi memengaruhi signifikan bagi kinerja karyawan; 5) Sarana kerja memengaruhi signifikan bagi kinerja dengan motivasi kerja sebagai variabel mediasi; 6) Kepemimpinan memengaruhi signifikan bagi kinerja dengan motivasi kerja sebagai variabel mediasi; 7) Dukungan manajemen memengaruhi penting bagi kinerja dengan motivasi kerja yang menjadi variabel mediasi; 8) Motivasi kerja memediasi pengaruh sarana kerja, kepemimpinan maupun dukungan manajemen pada kinerja karyawan.
Pengaruh Kepemimpinan, Lingkungan Kerja, Komunikasi dan Budaya Organisasi terhadap Kepuasan Kerja (Suatu Kajian Studi Literatur Manajemen Sumber Daya Manusia)
Authors: Ahmadi Umar Rikco , EHJ FoEh John , A. Manafe Henny , Sia Niha Simon
Published: April 2023

Abstract: This study will analyze leadership, work environment, and communication in influencing job satisfaction. The formulation of the problems in this study are: 1) Does leadership have a positive and important influence on employee job satisfaction?; 2) Does the work environment have a positive and important impact on worker job satisfaction?; 3) Does communication have a positive and important impact on employee job satisfaction?; 4) Does communication have a positive and important impact on employee job satisfaction; 5) Does leadership, work environment, communication, and organizational culture have a positive and important influence on employee job satisfaction?
Abstrak: Pada kajian ini akan menganalisis kepemimpinan, lingkungan kerja maupun komunikasi dalam memengaruhi kepuasan kerja. Rumusan masalah pada kajian ini, yakni: 1) Apakah  kepemimpinan memberi pengaruh positif dan penting kepada kepuasan kerja karyawan?; 2) Apakah  lingkungan kerja memberi akibat positif dan penting kepada kepuasan kerja pekerja?; 3) Apakah komunikasi memberi akibat positif dan penting kepada kepuasan kerja pekerja?; 4) Apakah komunikasi memberi akibat positif dan penting kepada kepuasan kerja pekerja; 5) Apakah kepemimpinan, lingkungan kerja, komunikasi dan budaya organisasi memberi pengaruh positif dan penting kepada kepuasan kerja karyawan.
Penguatan Manajemen Pengelolaan Pesantren Ainul Yaqin Kota Jambi
Authors: Rusmini Rusmini , Samsu Samsu , Dwi Nugroho Aris , Oryza Diandara , Hartoyo Zainal , Yulia Sari Sri , Miliani Masyrisal
Published: April 2023

Pesantren merupakan salah satu Lembaga yang memiliki peranan penting dalam mencapai tujuan Pendidikan. Di Provinsi Jambi terdapat lebih kurang 214 lembaga Pesantren. Pesantren ini terus berkembang, ada yang konvensional dan modern. Salah satu Pesantren Modern di Kota Jambi adalah Pesantren Ainul Yaqin. Pesantren Ainul Yaqin berdiri semenjak tahun 2001, namun kurang berkembang dan cenderung stagnan padahal berada di pusat kota. Berdasarkan observasi, masalah utamanya adalah  masalah manajemen, sehingga diperlukan pendampingan. Tujuan dari pendampingan adalah untuk meningkatkan kualitas pengelolaan Pesantren Ainul Yaqin Kota Jambi melalui pendampingan penguatan manajemen. Pendampingan dilakukan dengan menggunakan metode Participatory Action Research (PAR) dengan tahapan (a)Menyiapkan Community Action Plan (CAP) (b) Situation Analysis, (c)Doing with The Community, (d)The Inner Resources Approach, (e)Check (Evaluating and Controlling). Target pendampingan adalah komunitas Pesantren Ainul Yaqin Kota Jambi. Komunitas dipilih Setelah dilakukan studi pendahuluan dan wawancara. Penguatan manajemen pengelolaan berfokus pada manajemen pengelolaan Lembaga, manajemen personalia, manajemen kesiswaan, dan manajemen perpustakaan.
Notulae to the Italian flora of Algae, bryophtes, fungi and lichens: 15
Authors: Ravera Sonia , Puglisi Marta , Vizzini Alfredo , Totti Cecilia , Azzella Mattia M. , Bacilliere Giulia , Bolpagni Rossano , Breuss Othmar , Cogoni Annalena , De Giuseppe Antonio B. , Fačkovcová Zuzana , Faltner Felix , Gheza Gabriele , Giordani Paolo , Isocrono Deborah , Mair Petra , Malíček Jiří , Marino Pasquale , Mayrhofer Helmut , Nascimbene Juri , Ongaro Silvia , Paoli Luca , Passalacqua Nicodemo G. , Poponessi Silvia , Puntillo Domenico , Raimondo Francesco Maria , Sicoli Giovanni , Tratter Wilhelm
Published: April 2023

In this contribution, new data concerning Algae, bryophytes, fungi and lichens of the Italian flora are presented. It includes new records and confirmations for the algal genus Nitella, for the bryophyte genera Anthoceros, Dicranodontium, Fontinalis, and Riccia, the fungal genera Inocybe and Xerophorus, and the lichen genera Bagliettoa, Biatora, Calicium, Cladonia, Coniocarpon, Lecanora, Opegrapha, Placynthium, Rhizocarpon, Scytinium, Solenopsora, Stereocaulon, and Verrucaria.
A new Bolitoglossa (Amphibia, Caudata, Plethodontidae) from the Cordillera Oriental of Colombia
Authors: López-Perilla Yeny Rocio , Fernández-Roldán Juan David , Meza-Joya Fabio Leonardo , Medina-Rangel Guido Fabian
Published: April 2023

A new salamander species of the genus Bolitoglossa is here described from the cloud forests of the western slopes of the Cordillera Oriental of Colombia, in the Cundinamarca department. The most salient characters of this new species are its numerous maxillary and vomerine teeth, its moderate webbing on hands and feet, its short and robust tail, and its chromatic variation. Based on molecular analyses this new species is assigned to the adspersa species group and its status established as the sister species of B. adspersa, with which it was previously confused. Lastly, the distribution, natural history, and conservation status of the new species are discussed.
Modernité, tyrannie et crise
Authors: Marchal Kai , Quelennec Bruno
Published: April 2023

Cet article se demande si un dialogue entre la civilisation chinoise et Leo Strauss est possible et à quelles conditions. Il décrit le contexte d’introduction de Strauss en Chine, en se concentrant sur Liu Xiaofeng, l’un des straussiens les plus influents de la Chine contemporaine. L’analyse de son interprétation de la critique straussienne de la modernité occidentale fait ressortir deux distorsions fondamentales : là où Strauss considérait l’« enseignement tyrannique » comme quelque chose de théorique, Liu en fait un plan d’action politique ; au lieu de reconnaître la modernité des bases idéologiques de l’État fondé par Mao Zedong, il les interprète au crible de la tradition. Cette double déformation contredit l’intention de Strauss en tant que philosophe zététique et socratique.
Attractor of a nonlinear hybrid reaction–diffusion model of neuroendocrine transdifferentiation of human prostate cancer cells with time-lags
Authors: Zhao Kaihong
Published: April 2023

Prostate cancer is a serious disease that endangers men's health. The genetic mechanism and treatment of prostate cancer have attracted the attention of scientists. In this paper, we focus on the nonlinear mixed reaction diffusion dynamics model of neuroendocrine transdifferentiation of prostate cancer cells with time delays, and reveal the evolutionary mechanism of cancer cells mathematically. By applying operator semigroup theory and the comparison principle of parabolic equation, we study the global existence, uniqueness and boundedness of the positive solution for the model. Additionally, the global invariant set and compact attractor of the positive solution are obtained by Kuratowski's measure of noncompactness. Finally, we use the Pdepe toolbox of MATLAB to carry out numerical calculations and simulations on an example to check the correctness and effectiveness of our main results. Our results show that the delay has no effect on the existence, uniqueness, boundedness and invariant set of the solution, but will affect the attractor.
A conserved Caginalp phase-field system with two temperatures and a nonlinear coupling term based on heat conduction
Authors: Louvila Grace Noveli Belvy , Ntsokongo Armel Judice , Langa Franck Davhys Reval , Mampassi Benjamin
Published: April 2023

Our aim in this paper is to study generalizations of the Caginalp phase-field system based on a thermomechanical theory involving two temperatures and a nonlinear coupling. In particular, we prove well-posedness results. More precisely, the existence and uniqueness of solutions, the existence of the global attractor and the existence of an exponential attractor.
Becoming homebound by choice and constraint: a mixed-methods look into ageing and mobility transitions
Authors: Després Michel
Published: April 2023

This paper focuses on the transition of mobility practices and more specifically how certain older individuals experience patterns of Déprises leading them to adopt a more homebound lifestyle. As individuals age and advance in their life cycle, their capacities for mobility are prone to change, along with their lifestyles. Sometimes these changes are voluntary and done in a proactive manner, sometimes they are the product of external events. In some instances, following a transition period, these changes can result in a loss of mobility capacities, a continuation or reconfiguration of activities, or sometimes even an extension of mobility capacities, and therefore autonomy. As shown in earlier research, this process takes place in ways that are as diverse as the life course of each individual. This diversity, however, is still underrepresented in research, where older adults are often studied as a block according to their age (65+, 75+). This paper aims to delve deeper into the events and process leading to transition in mobility capacities among diverse profiles of older adults living in urban and suburban environments. To do so, the paper first presents results from statistical analysis showing how mobility practices can differ in older adults of different age groups representing different moments of the life cycle. Focusing afterward on a specific profile (the Stay-at-home), the article uses interview data to illustrate how diverse events, decisions and adaptation strategies led diverse individuals to become more homebound over the course of ageing. The article exposes a diversity of situations among Stay-at-home individuals, with transitions that are chosen or suffered. We conclude on strategies this plurality of Stay-at-home use to maintain their mobility and how we can support them to help them keep their autonomy.
Metropolitan mobility options and individual identities: How much households' mobility choices are determined by residential-related identities?
Authors: Lord Sébastien , Lamoureux Benjamin , Gerber Philippe
Published: April 2023

Daily mobility is an ordinary problem that fits into the complexity of everyday household life. Mobility is also a dimension of identity, a predisposition which gives individuals a specific framework for dealing with activities and travels. Thus, households’ choices are made with a wide range of rational elements (economic, time, accessibility, etc.), but also with more sensible elements (preferences, past experiences, satisfaction, etc.). In addition, large-scale urban projects aim to improve modal split and to facilitate households’ commutes conditions. Since poles of employment generate the main concentrated flows of urban travel, those poles are at the core of strategic planning. Beyond improving mobility, changing job location may involve contrasted issues for households, positive (e.g., travel efficiency, sustainable mobilities, etc.) and negative (e.g., freedom of choice, undesirable mode change). This paper focuses on an exceptional workplace relocation (2015) in Montréal – McGill University Health Center – and explores the daily commute choices for more than 10,000 metropolitan workers. While metropolitan accessibility is sharply improved, the new workplace offers a low-quality mobility environment compared to former ones (n=5) located downtown. What mobility choices do metropolitan employees make in order to rebuild their travel routines? What is the importance of both mobility habits and mobility identities in commute changes/satisfaction? Using an internet retrospective survey (n=1 977) conducted with the concerned workers, mobility strategies have been explored. Principal component analyses and clustering are used to take into account lifestyles typology into a logistic regression model in order to explain mode choice according to identities, workers’ socioeconomic characteristics, built environment and structural urban characteristics. Beyond the importance of accessibility, attitudes towards mobility have strong explanation power for specific workers' profiles. These variables should be better embraced by transportation plans.
Géoarchéologie portuaire de la cité de Cumes (Campanie, Italie)
Authors: Morhange Christophe , Stefaniuk Lise
Published: April 2023

La reconstitution paléo-environnementale obtenue de l’étude bio-sédimentologique des carottages permet d’affirmer que Cumes (région napolitaine, Italie) possédait, grâce à la présence de la lagune de Licola au nord de la cité, un abri côtier susceptible d’être utilisé comme port protégé dès l’époque archaïque. Néanmoins ce dernier devait être difficile d’accès via un grau. La présence de barres d’avant côtes à fleur d’eau rendait l’accès au chenal relativement périlleux. De plus, la migration au cours des siècles de ce dernier a dû également poser un problème délicat d’accessibilité pour les navires. Il faut aussi signaler les problèmes de colmatage accélérée de la lagune et les fluctuations du plan d’eau qui ont dû entraîner une adaptation régulière des structures portuaires et des relocalisations des installations. Les dynamiques géomorphologiques de la région de Cumes expliquent la rapide suprématie des ports proches mais moins contraignants comme Pouzzoles ou Misène aux dépens du médiocre abri côtier de Cumes-Licola. L’importance du bassin lagunaire de Cumes-Licola ne fit donc que décroître au fil des siècles jusqu’à disparaître, entièrement colmaté. À l’époque moderne seules de petites barques de pèche pouvaient encore circuler.
DESDOBRAMENTOS DA SÍNDROME PRÉ-MENSTRUAL SOBRE A SAÚDE MENTAL E O SONO : UMA REVISÃO SISTEMÁTICA
Authors: Laguila Altoé Isadora , Trannin de Mello Sônia , Francisquini Gardin Pamella
Published: April 2023

Objetivo: Analisar, mediante revisão sistemática, se aspectos como privação de sono, estresse e ansiedade estão relacionados com a síndrome pré-menstrual.

Metodologia: Trata-se de uma Revisão Sistemática que investigou nas bases de dados Biblioteca Virtual em Saúde (BVS). Foram utilizados os Descritores em Ciências  da  Saúde  “SPM”, “privação de sono”, “ansiedade”, "estresse" e "ciclo menstrual”, que foram  associados ao operador booleano “AND”. 

Resultados: As buscas resultaram em 369 artigos, dos quais 21 foram utilizados para a  composição  do  estudo.

Discussão: Ficou evidente que a privação de sono, estresse e ansiedade possuem relação com a SPM. Além disso, encontrou-se estudos ressaltando que aspectos cotidianos (trabalho e estudos), condições nutricionais e outros transtornos neurológicos (como depressão e compulsão alimentar) afetam e podem ser afetados pelos sintomas da síndrome pré-menstrual. Tratamentos promissores para a sintomatologia da SPM também foram foco de vários artigos encontrados, os quais utilizaram diferentes terapêuticas.

Conclusão: A síndrome pré-menstrual associa-se a diversos fatores, porém essa temática possui inúmeras controvérsias e interesses científicos divergentes o que impacta a quantidade e a qualidade de estudos disponíveis sobre o ciclo reprodutivo feminino e seus desdobramentos.
A INFLUÊNCIA DAS DISCIPLINAS AMBIENTAIS MINISTRADAS EM CURSOS UNIVERSITÁRIOS NA SEPARAÇÃO SELETIVA DE RESÍDUOS DOMÉSTICOS
Authors: Neves Moreira Amanda
Published: April 2023

O aumento da quantidade de resíduos sólidos tem levantado preocupações sobre o impacto em todo o mundo. Diante da intensificação da geração de resíduos, optou-se por questionar o possível impacto da carga horária das disciplinas ambientais da graduação na destinação dos resíduos. Assim, alguns cursos de graduação foram escolhidos, como: cursos noturnos da Universidade UniCesumar, como: Psicologia, Fisioterapia, Música, Engenharia de Software, Direito, Administração, Moda, Agronomia, Ciências Biológicas e Engenharia Civil. Posteriormente, foi necessário coletar as grades curriculares dos cursos, contendo disciplinas do primeiro ao último período. Para a classificação da carga horária, os cursos foram divididos em: nenhuma, uma, duas a três, quatro ou mais disciplinas relacionadas à ecologia ou sustentabilidade. A partir da categorização dos cursos, foi elaborado o questionário e definidas 16 questões, sendo 15 objetivas e 1 aberta. A coleta de dados foi realizada por meio de visita às salas do último período dos cursos. Com base nos dados coletados, verificamos que a maioria dos 52 alunos, que optaram por responder ao questionário, separavam o lixo doméstico. Entre a percentagem que não separa o lixo, analisa-se que 3 pessoas não o fazem porque não sabem fazer. Os dados mostraram que 86,5% das pessoas já conheciam sobre sustentabilidade e coleta seletiva. Destes, 33% afirmaram que seu conhecimento sobre o assunto aumentou após a graduação. Portanto, em nosso trabalho, verificamos que a separação do lixo doméstico não estava relacionada à carga horária dos cursos de graduação.
Test-Free Simulation Method for Blowout Preventer Pipe Shearing Powered by Data
Authors: Wang Yaou , Nault Chris , Givens Matthew , Zhang Hai Tao , Li Ke
Published: April 2023

A Blowout Preventer (BOP) serves as a safety valve in the drilling process in the oil and gas industry. It will be closed if an influx of formation fluids occurs and threatens the rig. A Ram BOP is one type of widely used BOP. It is composed of two ram blades, which will move toward each other to shear the drilling pipe and to close the valve. To ensure the shearing process is completed on the rig, lab tests are often run to evaluate the BOP’s capability and the required shearing pressure. Over the last decade, Finite element analysis (FEA) based simulation method has been set up to predict the shearing process. The simulation method still requires pipe damage parameters and requires lab test. This paper presents a test-free simulation method enabled by analyzing the ram BOP pipe shearing data, which significantly reduces the lead time and test costs.
The Chromatin Regulator Mll1 Supports T Follicular Helper Cell Differentiation by Controlling Expression of Bcl6, LEF-1, and TCF-1
Authors: Bélanger Simon , Haupt Sonya , Faliti Caterina E , Getzler Adam , Choi Jinyong , Diao Huitian , Karunadharma Pabalu P , Bild Nicholas A , Pipkin Matthew E , Crotty Shane
Published: April 2023

T follicular helper (TFH) cells are essential for developing protective Ab responses following vaccination. Greater understanding of the genetic program leading to TFH differentiation is needed. Chromatin modifications are central in the control of gene expression. However, detailed knowledge of how chromatin regulators (CRs) regulate differentiation of TFH cells is limited. We screened a large short hairpin RNA library targeting all known CRs in mice and identified the histone methyltransferase mixed lineage leukemia 1 (Mll1) as a positive regulator of TFH differentiation. Loss of Mll1 expression reduced formation of TFH cells following acute viral infection or protein immunization. In addition, expression of the TFH lineage–defining transcription factor Bcl6 was reduced in the absence of Mll1. Transcriptomics analysis identified Lef1 and Tcf7 as genes dependent on Mll1 for their expression, which provides one mechanism for the regulation of TFH differentiation by Mll1. Taken together, CRs such as Mll1 substantially influence TFH differentiation.
IL-18 Binding Protein–Producing Cells Attenuate Anemia in Murine Macrophage Activation Syndrome
Authors: Harel Mathilde , Fauteux-Daniel Sébastien , Rodriguez Emiliana , Palmer Gaby , Gabay Cem
Published: April 2023

IL-18 is a pleiotropic immunoregulatory cytokine of the IL-1 family. IL-18 has been identified as a potent IFN-γ inducer in synergy with IL-12 and IL-15 and thus as a powerful Th1 cell–polarizing cytokine. IL-18 activity is regulated by its naturally occurring soluble inhibitor IL-18 binding protein (IL-18BP), the production of which is stimulated by IFN-γ in a negative feedback loop. Circulating levels of IL-18BP are elevated, and unbound bioactive free IL-18 is thus not detectable in the circulation in physiologic conditions. However, emerging evidence indicates that the IL-18/IL-18BP balance could be dysregulated in macrophage activation syndrome (MAS), as mirrored by the presence of free IL-18 in the circulation of patients with MAS. Herein, we sought to identify IL-18BP-producing cells in a murine CpG-induced MAS model using IL-18BP knock-in tdTomato reporter mice. Endothelial cells, tissue-resident macrophages, and neutrophils appeared as major cellular sources of IL-18BP. We also identified extramedullary and medullary early erythroid progenitors as IL-18BP-producing cells in an IFN-γ-dependent manner. This finding suggests a novel regulation of IL-18 activity by erythroid precursors, which are likely involved in the prevention of the negative effects of IL-18 on erythropoiesis. Indeed, coherent in vivo and in vitro results indicate that IL-18 indirectly impairs erythropoiesis while favoring myelopoiesis and thus contributes to anemia associated with MAS and potentially with other IL-18-driven inflammatory diseases. In conclusion, IL-18BP production by endothelial cells, neutrophils, macrophages, and erythroid precursors attenuates the anemia associated with murine CpG-induced MAS.
S-97 RAIDER® GenHel Model Development and Correlation with Flight Test Data
Authors:   Sikorsky a Lockheed Martin Co., Xin Hong , Black Andrew , Herrmann Thomas , Jaeger Patricia , Luszcz Matthew , Smith Todd , Thorsen Adam , Zhang Chi
Published: April 2023

Flight dynamics models for engineering simulation are vital to rotorcraft design and testing. This paper focuses on a multi-year effort to develop and improve the S-97 RAIDER® flight dynamics model in State-Space GenHel and to correlate the model with flight test data. State-Space GenHel (SSGH) is an upgraded version of legacy GenHel with a series of new/enhanced modeling capabilities. The S-97 model has been used to support conceptual, preliminary, and detailed air vehicle design, control laws (CLAWS) design and tuning, handling qualities evaluation, flight loads development, system integration lab (SIL) testing, flight testing, and test pilot training. During the ongoing flight test program, the SSGH model has been continuously updated to improve correlation with the test data. The correlation spans a wide range of flight conditions including hover, low speed flight, level flight, chirp tests at different speeds, and various maneuvers. A series of reduced-order models and corrections were implemented in SSGH to capture the complicated physics missed in the baseline model. High-fidelity analytical tools and component test data were used to derive the parameters for these reduced-order models and corrections, with which the model-data correlation has been significantly improved. The paper also discusses the challenges in tip clearance prediction and in modeling the rotor on propeller interference. This study shows that an engineering model, continuously improved using appropriate methods, can capture the flight dynamics characteristics of a high-speed compound helicopter with sufficient accuracy for supporting CLAWS design and flight test.
Updating Rotorcraft Simulation Environments by Using Black-Box Input Filters
Authors:   Univ. of Applied Sciences Osnabrueck/Lingen, Greiser Steffen ,   CAE, Myrand-Lapierre Vincent ,   German Aerospace Center (DLR), Scepanovic Pavle ,   National Research Council of Canada, Gubbels Arthur , Nadeau-Beaulieu Michel , Seher-Weiß Susanne
Published: April 2023

Rotorcraft simulation environments such as training simulators or engineering simulations require high-fidelity models to be suitable for tasks such as pilot training, handling qualities analysis, and flight control system development. Deficits in model fidelity can arise from inaccurate data and unmodeled higher-order dynamic effects. Mitigating these deficits through physics-based modeling usually requires high effort. Therefore, a method is presented that improves a baseline simulation model by a “black-box” (i.e. non-physical) low-order input filter. The baseline can be a linear model or a nonlinear simulation model. Several options for deriving the input filter are elaborated and demonstrated in this paper using data from the CH-47, AH 135, and Bell 412 helicopters. In all cases the simulation fidelity was improved by approximately a factor of two.
Development of a Reconfigurable Control Equivalent Turbulence Input Model for Multirotor UAS
Authors:   San Jose State University, Truong Kevin ,   US Army CCDC AvMC, Berger Tom ,   University of Portland, Ivler Christina , Gong Anthony , Tischler Mark
Published: April 2023

The control equivalent turbulence input (CETI) modeling approach uses flight data taken in turbulence and identifies control inputs that would effectively reproduce the aircraft’s response to turbulence. CETI models are extracted and presented for a quad-, hexa- and octocopter using flight test data collected in different wind conditions. Time domain simulation of the developed turbulence models is verified with flight test data. The effects of wind intensity are studied by comparing extracted turbulence models against the collected wind information. The effects of output measurement noise on CETI model identification are studied in simulation as well. The implications of these findings are discussed in relation to the development of a reconfigurable CETI model for multirotor UAS.
Experimental Investigation of Unsteady Inflow for a Helicopter Model in Shipboard Operations
Authors:   Politecnico di Milano, Taymourtash Neda , Gibertini Giuseppe , Quaranta Giuseppe , Zanotti Alex
Published: April 2023

State-space representation of the dynamic inflow is an essential element in rotorcraft flight mechanics modeling and simulation. Identification of a reliable low-order model which is able to predict the transient response of the inflow as well as the steady part, becomes even more important during the maneuvering flights. The objective of this paper is to exploit an experimental setup, consists of a helicopter model and a simplified ship geometry, to investigate the possible effect of the wake interactions with environmental elements such as ground effect or airwake of the ship, on the time constants associated with the buildup of the inflow states. A series of wind tunnel tests were performed, simulating various flight conditions, including hover and forward flight, inside and outside of the ground effect, and the rotor over the deck of the SFS1 at two different positions with respect to the ship super-structure, with the wind coming from two different directions. After trimming the rotor at each flight condition, a sequence of pitch excitation commands were applied to the collective, lateral and longitudinal cyclic in order to excite the induced flow of the rotor. The frequency analysis of the measured aerodynamic loads shows the variation of the time lag, while rotor is operating in the same trim condition, but different positions with respect to the ground or the flight deck.
Advanced Manufacturing in Sustainment
Authors:   Sikorsky a Lockheed Martin Co., Woodworth Heather , Mark Alexander , Slezak Caitlyn
Published: April 2023

Sustainment is the most important part of the aircraft life cycle. After a production program ends there are decades of work to support the aircraft that are flying in the fleet. The average aircraft age of the B-52 is 55 years old as of today. With a decommission estimate of 2040, the fleet's age could hit 90 years of sustainment of a given aircraft. These aircraft require both planned and unplanned maintenance, which requires the original equipment manufacturer (OEM) to supply spare parts. When the required spare parts are not available, it can result in aircraft on ground (AOG) events and missions unable to be flown. During production, an OEM's suppliers have a steady cadence of part orders which results in a steady flow of parts through their facility. Over the lifecycle of sustainment, part orders are more likely to come in smaller quantities and at unpredictable intervals. This results in suppliers needing to start and stop their production lines for these parts, or the need to inventory parts, which creates several challenges. It is not easy to restart a production line. For some parts there is still the element of tacit knowledge that is essential to manufacturing the parts. If there is a break in production, the tacit knowledge can be lost causing a long process to restart production, resulting in increased scrap and longer than normal lead times. Breaks in the production flow also result in suppliers focusing their resources on other projects, so capacity is not guaranteed when a sustainment order is needed. Further, because many sustainment parts were designed decades ago using manufacturing processes that were most robust during that time period, many advanced technologies for manufacturing are not applied to sustainment parts. As time goes on, parts with multiple sources become parts with sole sources or worse, they become obsolete. Options for procurement become limited, often requiring protracted negotiations and requiring the OEM to accept long lead times, unit cost increases, requests to reimburse the supplier for non-recurring expenses (NRE) to re-start the line, and/or large minimum buy quantities. If parts have become obsolete, then efforts are typically initiated to qualify a new supplier to build the parts as originally designed or to qualify a replacement part that is very similar to the original. This can be an effective approach for some parts and suppliers, but it is a time consuming and costly strategy that can still be ineffective in the end. Using the advanced technologies that have been developed since their original design are a much more effective, responsive, and flexible approach to addressing these supply challenges.
New Flying Craft with no Exterior Moving Parts
Authors:   Tom Daily Contracting LLC, Daily Tom
Published: April 2023

In this you will find The New Ducted Wing Propulsion System (Figure 1) and the Four Port Propulsion System (Figure 2) with no exterior moving rotor blades. The Hoppers fan blades are enclosed in the fan chamber making it stealthy, quiet, safe, and efficient. Having no exterior moving parts makes the Hopper safe to operate compared to a helicopter. The steering flaps are all internal flaps. The thrust force in the Hoppers fan chamber is going up and not down like helicopters and rockets. The thrust force is flowing upward into the ducted wing. The ducted wing is curved to bend the air flow back towards the ground to give lift. There is a G force added to the airflow when bending the ducting back towards the ground. More testing is needed to see what effect the G force has on the airflow thrust force.
Digital Displacement Hydrostatic Transmission for Rotorcraft and Distributed Propulsion
Authors:   Flowcopter Ltd., Caldwell Niall ,   University of Sherbrooke, Rancourt David , McCurry Peter , Stein Uwe
Published: April 2023

This paper introduces a new series-hybrid digital transmission technology for distributed propulsion systems offering a lower cost, a lighter weight and more environmental tolerance than series-electric-hybrid powertrains. In particular, this concept can be used on large multicopters for applications requiring long range, heavy payloads and continuous hover, such as offshore search and rescue, surveillance and logistics. The concept, design principles and analysis are described to allow component sizing and calculation of operating point under steady state and dynamic conditions. A design is described for a quadcopter with maximum take-off weight of 380kg, including a Rotax 915 engine, a Digital Displacement® hydraulic pump and bent-axis motors. The components of the propulsion system are described and compared to an equivalent electric system, showing lower cost and weight, and similar efficiency. A computationally efficient model is described of the rotor behavior allowing rapid simulation with accurate rotor loads. A 6 DOF vehicle simulation is described, including dynamics of the proposed system, coupled to a flight controller. Results show that such a standard flight controller can fly the proposed system under a range of conditions including at the engine power limit. The expected flight endurance of the 380kg quadcopter is over 6 hours and range over 1000km depending on payload. Test rigs are described, including at full scale for the 380 kg study, which demonstrate stable control of hover. Other applications for distributed propulsion are discussed.
Optimizing Turbogenerators for Hybrid-Electric Applications
Authors:   New Centerline Design, Heathco Craig
Published: April 2023

Advancements in distributed electric propulsion have given rise to a wide array of new eVTOL designs featuring tilt rotors, tilt wings and ducted fans. All of these systems pose a common challenge, meeting the electrical power demands of the propulsors. Hybrid-electric drives which combine an engine driven generator with batteries are being pursued to address the range and payload limitations of all electric drives using only batteries. The hybrid systems currently being considered rely on traditional gasoline, diesel, and turbine engines. Gas turbines offer exceptional energy density but are less fuel efficient than piston engines. Two technologies, heat recovery and power transfer, can be incorporated into the gas turbine to significantly improve fuel efficiency. New Centerline Design has conducted parametric trade studies on eVTOL aircraft with turbine based hybrid-electric systems to quantify the benefits that heat recovery and power transfer will have on eVTOL payload and range. The results of this study show that heat recovered gas turbines with power transfer are excellent candidates for next generation eVTOL hybrid-electric propulsion systems.