bluuebunny/crossref_metadata_2025 huggingface dataset:
Peculiarities of the judicial review of administrative cases regarding the granting of special permits for the use of subsoil
Authors: Skochylias-Pavliv O.V.
Published: November 2023

The article is devoted to the study of the peculiarities of judicial review of administrative cases regarding the granting of special permits for the use of subsoil. It is indicated that in relations related to the use of subsoil, disputes usually arise between individuals or legal entities and the subject of authority regarding the appeal of his decisions (normative legal acts or individual acts), actions or inaction.

It was established that a significant part of administrative cases regarding the granting of special permits for the use of subsoil arose in connection with the fact that there was a change in the normative and legal regulation of the conditions for granting special permits during the period when the plaintiff went through the procedures for obtaining such a permit. In connection with this, different approaches to solving the specified category of cases arose in judicial practice. Some courts believed that the subject of power should be guided by the legislation in force at the time the plaintiff addressed the relevant application to the state authority, and not by the legislation in force at the time of the decision, justifying their position by the fact that all doubts regarding the application of the norms national legislation must be interpreted in favor of the person, not the body. The opposite position of the courts was that the subject of the authority can act solely on the basis and within the limits of the powers defined by the legislation and thus is obliged to be guided by the legislation in force at the time of consideration of the application for the granting of a special permit, and not by the legislation that was in effect on the date of the plaintiff's appeal to the state authority.

It is proved that the practice of consideration of this category of cases is important and useful in view of the fact that it gave grounds for the formation of established judicial practice in the conditions of changes in the legislation on ongoing legal relations. If, during the consideration of a person's application by a subject of authority before making a final decision, the legal regulation was changed, the subject of authority does not have legal opportunities to make a decision taking into account the previous legal regulation, which is invalid. Thus, the subject of power must apply the legislation that was in force at the time of the decision, even if the legal regulation has been changed.
Decent pay for work as one of the important factors of material encouragement of civil servants
Authors: Yaroshenko O.M.
Published: November 2023

The article is devoted to the issue of remuneration of civil servants as one of the important factors of their material encouragement in civil service. The importance of the civil service, the main task of which is to effectively ensure the complex interrelated activities of employees aimed at the development and implementation of state policy and management decisions, the implementation of regulatory and service functions in the interests of society, is noted. It was noted that one of the strategic tasks is the reform of the civil service of Ukraine, one of the directions of which is the remuneration of civil servants. This is emphasized in the State Administration Reform Strategy of Ukraine for 2022-2025, approved by the Cabinet of Ministers of Ukraine order dated July 21, 2021, one of the tasks of which is to carry out a comprehensive reform of the system of payment of civil servants. Therefore, taking into account modern challenges, new theoretical and practical approaches to solving problems related to remuneration, in particular the remuneration of civil servants as one of the important factors of their material stimulation in today's conditions, are proposed. A proposal was made, supporting other researchers in this field, in the process of reforming the remuneration of civil servants to regulate, firstly, the level of the salary of employees of the local, district, regional state administration or the central body of executive power in an equal amount, that is, it should be the same at all levels salary; secondly, additional incentive payments (allowances and bonuses) to civil servants; thirdly, means of motivating civil servants with additional social guarantees (for example, free annual preventive medical examination, sanatorium-resort treatment). It is noted that today the state is already taking certain steps in this direction. Thus, Prime Minister D. Shmyhal predicts the introduction of a new system of payment of civil servants from January 1, 2024. According to him, "the main goal of the civil service pay reform is justice and elimination of abuses. Changes in wages are aimed at reducing disparities and a fair approach to setting the wages of civil servants. The new system will strengthen the role of official salary and help eliminate abuses during the calculation of additional payments and bonuses.”
Criminal legal protection of pharmaceutical activity on the circulation of medicinal products in acts of foreign criminal legislation
Authors: Frolova O.G.
Published: November 2023

The article examines the issue of the specifics of the criminal law protection of pharmaceutical activity in the circulation of medicinal products in acts of foreign criminal legislation.

The author proposes to single out the most typical types of criminal offenses that encroach on pharmaceutical activity depending on the typical types of "impact” of pharmaceutical activity, namely when ensuring various stages of trade and other circulation (turnover) of medicinal products and other items of pharmaceutical activity.

The author conducts a thorough review of the criminal legislation of such countries as the Federal Republic of Germany, the Republic of Austria, the Swiss Confederation, the Kingdom of Spain, the Republic of Estonia, the Republic of Poland, Turkey, Romania, the Republic of Kazakhstan, the Kyrgyz Republic, the Republic of Uzbekistan, the Republic of Moldova, the Republic of Tajikistan and the Republic of Azerbaijan . Such acts of criminal legislation are analyzed from the point of view of the scope of criminal legal protection of the sphere of circulation of medicinal products and in relation to the norms defined in the criminal legislation of Ukraine.

The article notes that the provisions of acts of foreign criminal legislation establish typical and atypical types of criminal offenses that encroach on pharmaceutical activity as an independent object of criminal law protection.

The author's attention is drawn to the fact that acts of foreign legislation define both a more "broad" and a smaller ("narrow") scope of criminal offenses of a specific type. And in separate acts of foreign criminal legislation, the concept of illegal medicinal products trafficking as an independent type of criminal offense is defined in different ways.

It is noted that the conducted comparative legal research demonstrated that the most complete scope of criminal legal protection of circulation of medicinal products and circulation of medical devices as elements of pharmaceutical activity is presented in the German and Swiss "models" of criminal legal protection. These models of criminal law protection received a detailed review and analysis, due to the detailed provisions of the criminal legislation of the Federal Republic of Germany and the Swiss Confederation.
Mobile telecommunication devices as carriers of important evidentiary information: prospects and research problems
Authors: Kurman O.V.
Published: November 2023

The article is devoted to the problems of studying modern mobile telecommunications. The relevance of the work is determined by the fact that today there is no sphere of public life where modern electronic means of communication are not used. Any activity to maintain its level requires the active use of modern technical communicators that allow almost instantaneous receipt, processing, and sending of large amounts of information. A significant part of such technical devices are mobile phones or smartphones, which are one of the most common tools (means) in the commission of criminal offences.

A mobile phone, like any other instrument or means of committing a crime, leaves traces in space and time when it is used. Some of these traces are electronic (digital), which are stored on the phone itself. The research paper examines the main ways to obtain information stored on a mobile device, in particular, through: 1) inspection of the device at the scene of the incident; 2) investigative inspection of the device already seized during criminal proceedings; 3) appointment and conduct of forensic examination. The investigative examination has a serious advantage over the appointment of an expert examination in the context of the speed of its conduct and obtaining results. This is a very important factor, especially if the required information is either small in volume or in the public domain. However, the review completely excludes the process of examining the phone. A detailed investigation is part of a forensic examination, which is a much longer process in terms of procedural, organisational and technical aspects. However, the amount of information obtained in this case is incomparably greater and some of the information can be obtained only through in-depth analysis of the contents of the mobile device. In addition to the prospects of these approaches, the paper also highlights some problems associated with the preparation and conduct of expert investigations of mobile phones or smartphones, in particular, procedural and technical ones (the need to obtain permits for the use of destructive research methods, the lack of necessary technical and software equipment for experts, etc.).
Surgimiento y consolidación del Estado islámico
Authors: Ruiz Figueroa Manuel
Published: November 2023

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La "tribu" a la vuelta de la esquina: ¿el retorno de lo exótico? Comentario al artículo de B. LaBrack y K. Leonard, "Conflicto y compatibilidad entre las familias inmigrantes punjabi-mexicanas de las zonas rurales de Califronia, 1915-1965"
Authors: Devalle Susana B. C.
Published: November 2023

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Réplica a Devalle
Authors: Leonard Karen , Labrack Bruce
Published: November 2023

Traducción del inglés: Mariela Álvarez Peñaloza
Panorama visto desde el puente
Authors: Galeano Massera Jorge
Published: November 2023

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La política exterior del Vietnam socialista: la primera década
Authors: Novelo Adriana
Published: November 2023

Traducción del inglés: Mariela Álvarez
Coloquio sobre los ritos funerarios en Asia
Authors: - - -
Published: November 2023

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Las ofrendas funerarias en la Mesopotamia
Authors: Silva Castillo Jorge
Published: November 2023

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El otro Pacífico: mitos y realidad
Authors: Devalle Susana B. C.
Published: November 2023

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La naturaleza de la guerra de Vietnam
Authors: Lockhart Greg
Published: November 2023

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Jonathan Z. Smith, To Take Place: Toward Theory in Ritual, The University of Chicago Press, Chicago y Londres, 1987, 183 pp.
Authors: Lorenzen David N.
Published: November 2023

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Alan Piazza, Food Consumption and Nutritional Status in the PRC, Westview Press, Boulder y Londres, 1986, 249 pp.
Authors: Gutiérrez Chong Natividad
Published: November 2023

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Model of stochastic auctions using level market index
Authors: Maksim Nikonov , Alexei Shishkin , Dmitry Konev , Aleksandr Dolmatov
Published: November 2023

The following research paper is devoted to the complex topic of modeling stochastic financial markets using the example of auction markets. The presented model for market makers’ behavior on stochastic auction markets contributes practically to the field of studying portfolio optimization, risk management, market participants’ balance processes, and prediction problems via cutting-edge machine learning and statistics approaches. The reliability of the given model is proved practically with the help of modern machine learning methods of validation, namely, combinatorial splits. A client-server model for remote simulation was implemented, as well as interpreted language in C++. XGBoost, Catboost, LSTM, NN Ensemble, and H2O Auto-ML models were considered in the course of building the decision model. Hyperparameters were obtained via Optuna. Besides that, the developed model was backtested on historical data of different financial assets, starting with stocks and ending with commodity prices and foreign exchange rates. Within all models, positive Sharpe ratios have been obtained, which indicates the robustness of the model. The paper offers a valuable framework for market maker decision-making stochastic modeling, examining its pricing mechanisms and financial risk management as crucial for exchanges, funds, and other financial institutions, which makes it relevant in the context of the current dynamics of the development of financial markets and the increase in trading volumes.
Targeting H3N2 influenza virus RNA dependent RNA polymerase dependent inhibitory activity by principal components from latex of Calotropis gigantean
Authors: Sharma Arun Dev , Kaur Inderjeet , Chauhan Amrita
Published: November 2023

The H3N2 influenza virus is spiking dramatically, which is a major concern worldwide and in India. The multifunctional hetero-trimer influenza virus RNA-dependent RNA polymerase (RdRP) is involved in the generation of viral mRNA and is crucial for viral infectivity, which is directly related to the virus’s ability to survive. The goal of the current work was to use molecular docking to determine how the RdRP protein might be affected by powerful bioactive chemicals found in Calotropis gigantia latex. By applying CB-dock 2 analysis and 2D interactions, an in-silico docking study was conducted using a GC-FID (gas chromatography with flame-ionization detection) based composition profile. Tocospiro A (15%), Amyrin (7%), and Gombasterol A were found by GC-FID to be the main phytocompounds in the latex of Calotropis gigantia. The docking result showed that ligands were effectively bound to RdRP. According to interaction studies, RdRP/ligand complexes create hydrogen bonds, van der Waals forces, pi-alkyl bonds, alkyl bonds, and pi-Sigma bonds. Therefore, it was suggested that Calotropis gigantia latex may represent a possible herbal remedy to attenuate H3N2 infections based on the above findings of the fragrance profile and docking.
Mitsprache oder Mitbestimmung?
Authors: Flach Leonard
Published: November 2023

This article addresses the questions of the foreign policy competencies of the Federal Assembly and how it made use of them in the negotiation of the institutional framework agreement with the EU. After a historical classification and a discussion of the relevant legal basis, the author undertakes a computer-aided content analysis of the parliamentary debates on the agreement in the Official Bulletin of the Federal Assembly. The results are then analyzed with recourse to previous insights. In doing so, he shows that there is an interplay between the expansion of parliamentary powers and diminishing opportunities for shaping them and that the Federal Assembly strives to fulfill its partial responsibility for foreign policy. In his conclusions, the author states that the increasing internationalization challenges the cooperation between the Federal Assembly and the Federal Council and that the rights to information and consultation play a key role in this debate.
Association of Anthropometric Measures with cardiovascular risk features in children and teenagers in Albania
Authors: Shkurti Enkelejda , Shtiza Diamant
Published: November 2023

We performed this study to establish the association among anthropometric amplitudes with cardiovascular hazard aspects and metabolic syndrome (MetS) in normal-weight Albanian children and adolescents. We examined the data of 3,658 children and adolescents (46.8% boys), aged 10-17 years, with a normal BMI (4th-83th percentile) obtained from a ‘Childhood and Adolescence Monitoring and Prevention of Adult Non-communicable Disease’ study. The International Diabetes Federation agreement classified the diagnostic criteria for MetS. The prevalence of MetS for 10- to 12.5-year-old boys, 14- to 17-year-old boys, 10- to 13.7-year-old girls, and 14- to 17-year-old girls were 1.3, 2.4, 2.1, and 2.9%, correspondingly. After adjusting age and sex, each item’s expansion in BMI (within normal range) and waist circumference enhanced the odds of MetS from 4 to 65 % and from 1 to 17 %, consequently. The main pattern of dyslipidemia among the respondents was elevated triglycerides and low high-density lipoprotein cholesterol. Our study strengthened the latest research on the elevated frequency of metabolic risk factors among normal-weight individuals in the pediatric age group.
Study of Low Frequency Magnetic Field of Indoor Distribution Substations
Authors: Pavel Ionel , David Valeriu
Published: November 2023

In this paper we presented some measurements of the low frequency magnetic field from indoor distribution substation. Using two automatic measuring instruments we made both spot measurement and automatic long-term survey presenting the spatial and temporal variability of the magnetic field in five areas with indoor distribution substation. Correlating the time of spot measurement, with that of automatic survey we estimate the magnetic field values to reduce the errors due to the temporal variation. With the values obtained after estimating the field, we draw maps for the entire zone of an indoor distribution substation. The results were compared with the maximum permissible limits by national and international standards and we found that they were not exceeded. However, in all five areas the values of the magnetic field were above the threshold of 400 nT taking into account long-term exposure, which can lead to biological effects on health, especially for children.
Thinking Social Management from the Epistemologies of the South
Authors: Do Carmo Gisleine , Rezende Vânia Aparecida , Silva Camila de Assis , Pereira José Roberto , Da Silva Cristiane Aparecida
Published: November 2023

Research objective: To make theoretical approximations between the field of Social Management and Southern Epistemologies.
 
Theoretical framework: Social Management represents an alternative to hegemonic organizational thinking. Through public spheres, permeated by participatory and dialogic actions, the aim is to serve the common good of society. Southern Epistemologies represent an alternative to the epistemological paradigm of modern science, the colonial, patriarchal and capitalist side.
 
Results: Just as Social Management seeks emancipation as its purpose, Southern Epistemologies present emancipatory potential, by constituting political and epistemic guidance, which arises from knowledge about the fight against capitalism/colonialism/patriarchy.
 
Originality: There is a need to advance in the understanding of Social Management, based on its original epistemological and decolonial axiological sense, considering the emergence of debates about inequalities and diversities. Therefore, Southern Epistemologies become relevant to reflect the field, as it admits the knowledge produced in modernity and is based on a counter-hegemonic conception.
 
Theoretical contributions: From the perspective of Southern Epistemologies, Social Management, as a possibility of epistemological decoloniality, becomes more appropriate to the Latin American context and closer to a dialogical management that seeks to free individuals and promote equality through promotion of the common good. Thus, space is opened for the appreciation and validation of knowledge built in Latin America.
Assessment of knowledge and awareness regarding plantar fasciitis among the Qassim population: a cross-sectional observational study
Authors: Alayed Faisal , Alkhalifah Khalid , Alharbi Abdulmajeed , Alzahrani Abdulaziz , Almotiri Mohammad , Almasaud Abdulelah , Alrashdi Alanoud , Ahmed Abdourahman
Published: November 2023

Objective:
To evaluate and assess the knowledge and awareness about plantar fasciitis (PF) among the Qassim population.
Methods:
A cross-sectional study was conducted among the general population who lived in the province of Qassim, Saudi Arabia, through a self-administered questionnaire.
Results:
A total of 859 participants were included in this study. Females (50.6%) were slightly more in number than males (49.4%). Most participants were aged 15‒24 years (31.4%), while the age group older than 55 years contained the least participants (7%). Most participants (67.4%) had college degree. Regarding nationality, 833 (97%) were Saudis. When participants were asked about their location, the most common area was Buraydah (52.9%). The results indicated that there was a moderately poor level of awareness among the participants. There was a statistically significant difference between the level of education and awareness. There were no statistically significant differences between other variables (gender, age, nationality, and address) and awareness.
Conclusion:
Overall this study found that knowledge and awareness of PF was poor in the general population despite the commonness of the disease. It was noticed that there is obvious confusion about the disease and its diagnosis.
Hemp Fibres: Essentials, Composites or Nanocomposites and Technical Applications
Authors: Kausar Ayesha , Ahmad Ishaq
Published: November 2023

In this article, we overview a very important type of natural fibre, namely, hemp fibre. We consider the exclusive structure, properties, modification, the composite or nanocomposite formation and exceptional application zones. Industrial hemp fibres have been commonly developed and possess high cellulose amounts. The long hemp fibres can be termed bast or flax fibres. Hemp fibres are eco-friendly, and have light weightiness and stiffness properties. Consequently, to enhance the use of hemp fibres at engineering level, research has focused on improving the mechanical or thermal and high-tech features of these fibres. In doing this, the surface modification or treatment of hemp fibres has been notably considered. The modified fibres have been found valuable for developing certain derived materials such as polymeric composites and nanocomposites in particular. Consequently, including hemp fibres as additives in composite or nanocomposite matrices has been explored for manufacturing high performance ecological, recyclable, biodegradable and sustainable materials. Application areas identified for the hemp and related composites or nanocomposites include the synchrotron and neutron scattering, water treatment aiming dye removal, automobiles, textiles and construction. However, there is insufficient literature on these technologically important fibres and ensuing materials. Comprehensive future efforts may better resolve the challenges regarding reproducibility and long life-cycle high-tech applications of hemp fibres.
CONTRIBUTION OF NAD(P)H:FMN-OXIDOREDUCTASE ACTIVITY INTO VISCOUS MEDIUM EFFECTS ON KINETICS OF COUPLED ENZYME SYSTEM FROM LUMINOUS BACTERIA
Authors:   Surgut State University, Sutormin O.S. , Nemtseva E.V. , Tyrtyshnaya Y.S. , Petrova Yu.Yu. , Kratasuyk V.A. ,   Siberian Federal University, Krasnoyarsk
Published: November 2023

This study examined the effects of glycerol and sucrose on the coupled reactions of NAD(P)H:FMN-oxidoreductase of luminous bacteria in vitro, providing valuable information regarding microenvironment of the enzyme and its function.
RDH12, DELIVERED BY AAV8 AND AAV9 VECTORS, RESTORES RETINOL DEHYDROGENASE FUNCTION IN VITRO
Authors:   Sirius University of Science and Technology, Sochi, Gurtsieva D.T. , Egorov A.D. , Minskaia E.S. , Brovin A.N. , Zhuravleva S.V. , Tumaev A.V. , Karabelsky A.V.
Published: November 2023

Leber congenital amaurosis (LCA), one of the main causes of blindness in children, accounts for at least 5 % of all retinal dystrophies. To date, at least 26 LCA-causing genes (mostly inherited in an autosomal recessive manner) with more than 400 mutations have been identified [1]. Defects in Retinol Dehydrogenase 12 (RDH12), an NADPH-dependent retinal reductase displaying high activity toward 9-cis and all-trans-retinol and participating in the metabolism of short-chain aldehydes, cause LCA type 12 and Retinitis Pigmentosa 53 [2].
RECOMBINATION AND MODULAR EVOLUTION OF POSITIVE-STRAND RNA VIRUSES
Authors:   1Martsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Disease of Sechenov University, Moscow, Aleshina Yu.A. , Orlov A.V. , Lukashev A.N. ,   Lomonosov Moscow State University,   Research Institute for Systems Biology and Medicine, Moscow
Published: November 2023

Recombination is one of the major forces generating genetic diversity in positive-strand RNA viruses. We systematically analyzed patterns of natural recombination in four (+)RNA virus families — Astroviridae, Caliciviridae, Picornaviridae and Coronaviridae, using both classical recombination detection methods and by comparing correspondence of genetic distances in different genome regions.
Uso de instrumentos de rastreio de transtornos mentais na Atenção Básica
Authors: Medeiros Sara Rezende , Araújo Marília Daniella Machado , Jeronymo Daniela Viganó Zanoti , Malaquias Tatiana da Silva Melo , Borba Kátia Pereira de , Silva Dannyele Cristina da , Massuqueto Raphaella Rosa Horst , Baratieri Tatiane
Published: November 2023

Objetivo: Analisar o uso de instrumentos de rastreio de transtornos mentais comuns na Atenção Básica. Métodos: Revisão integrativa da literatura realizada na Biblioteca Virtual em Saúde e PubMed. Considerando os critérios de elegibilidade, foram selecionados 25 estudos publicados no período de 2010 a 2020. Resultados: Houve predomínio da autoria na área da Medicina, quatro teve colaboração da Enfermagem, com apenas um de autoria exclusiva. Todos os estudos quantitativos, sendo dois metodológicos. Os instrumentos mais utilizados foram a Escala de Depressão Geriátrica, Mini International Neuropsychiatric Interview e suas variações, Escala Hospitalar de Ansiedade e Depressão, WHO Composite International Diagnostic Interview e o Patient Health Questionnaire. Verificou-se três finalidades distintas para as escalas: estimar a prevalência de transtornos mentais; como uma etapa da pesquisa; e para rastreio dos transtornos mentais. Considerações Finais: Considera-se que os instrumentos de rastreio são de fácil aplicação e úteis para a prevenção e promoção da saúde mental na Atenção Básica.
Efeito da intervenção educativa de suporte básico de vida em ambiente escolar
Authors: Ribeiro Larissa Ellen Silva , Santos Giancarla Aparecida Botelho , Santana Priscila Freire Pereira , Dourado Stela Márcia Pereira , Bueno Filho Júlio Sílvio de Sousa , Barroso Camila Marques , Graciano Miriam Monteiro de Castro
Published: November 2023

Objetivo: Avaliar os efeitos da intervenção educativa sobre os conhecimentos de Suporte Básico de Vida Pediátrico (SBVP) de professores em diferentes tempos. Métodos: Estudo longitudinal do tipo antes e depois. A amostra estudada contemplou 250 professores do Ensino Fundamental I. Os dados foram coletados por meio de questionários de autopreenchimento. O conhecimento foi analisado aplicando-se a Teoria de Resposta ao Item de dois parâmetros e análise de Regressão Múltipla Ponderada. Por fim, foi aplicado o teste Tukey para análise do efeito das interações entre os testes nos diferentes tempos, adotando-se 5% de nível de significância. Resultados: Os professores apresentaram conhecimento prévio em SBVP significativamente inferior em comparação aos demais testes aplicados após intervenção educativa. Houve aumento significativo da estimativa média de acerto das questões avaliadas imediatamente após o treinamento inicial, revelando aquisição de conhecimento. Não houve perda significativa de conhecimento em SBVP pelos professores, indicando retenção acima de 90% mesmo após 6 meses do treinamento inicial. Conclusão: O treinamento reforço colaborou significativamente com nova aquisição de conhecimento, demonstrando o efeito complementar da Intervenção Educativa sobre SBVP. O método de intervenção educativa adotado no estudo se revelou capaz de promover a aquisição e a retenção expressiva do conhecimento ao professor.
Rathke’s cleft cysts causing Cushing’s disease: Two unique cases and review of the literature
Authors: Maddy Krisna , Luther Evan , Berry Katherine , Lu Victor M. , Shah Ashish , Ivan Michael E. , Komotar Ricardo J.
Published: November 2023

Background:

The presentation of isolated Rathke’s cleft cysts (RCC) without any associated pituitary adenoma in patients with symptoms consistent with Cushing’s disease (CD) remains exceedingly rare. As such, we aim to present two cases of RCC presenting with CD with a resultant resolution of their CD following surgical resection.

Case Description:

Here, we present two cases of RCCs presenting with symptoms suggestive of CD. A functional pituitary microadenoma was the presumed diagnosis based on initial clinical presentation and diagnostic imaging suggesting a pituitary lesion. However, pathology results demonstrated no evidence of adenoma but cysts lined with columnar epithelia consistent with RCC. Complete surgical resection was achieved in both patients through endoscopic endonasal pituitary resection with postoperative symptomatic resolution and normalization of cortisol levels. In addition, we discuss the literature on this rare presentation and suggest a pathological mechanism for this unique presentation of RCC-causing CD.

Conclusion:

Surgical resection of RCC may provide a “biochemical cure” for patients presenting with CD, as demonstrated by these two unique cases. The clinical features, histological findings, and possible pathological mechanisms for this unique presentation of RCC causing CD discussed lay the groundwork for future studies into the pathophysiology of RCC and CD.
Modernization of Higher Education Programs as Factor of Developing Human Resources Potential of Regional Labor Market under Digitalization of Economy
Authors: Бабскова О.В. , Чумаков В.Н. , Воронова Д.Ю.
Published: November 2023

Вусловиях цифровизации экономики возрастает роль кадрового потенциала рынка труда и меняются требования к профессиональным компетенциям персонала, формируются предпосылки к структурным диспропорциям в спросе и предложении определенных профессий. Под воздействием данных факторов возникает острая необходимость модернизации образовательных программ высшего образования. В статье проведен анализ структуры рынка труда Ленинградской области, а именно: вакансий по профессиональным сферам; дифференциации hh.индекса, отражающего количество резюме на одну размещенную вакансию. Выявлена необходимость покрытия дефицита кадров в регионе за счет выпускников образовательных организаций высшего образования Ленинградской области. Предложены рекомендации по разработке образовательных программ с возможностью получения дополнительного профессионального образования, направленного на формирование цифровых компетенций, что обеспечит конкурентоспособность выпускников вузов в цифровой экономике и развитие кадрового потенциала региона.

Under the digitalization of economy, we see the increasing significance of human resources potential of the labor marketand changing requirements to professional competencies of personnel. The prerequisites for structural imbalances in the supply and demand of certain professions are developing. The factors in question determine an urgent need to modernize educational programs of higher education. We analyzethe structure of the labor market of Leningrad region, namely, the vacancies in various professional fields, the differentiation of the hh.index reflecting the number of resumes per a posted vacancy. The need to cover the personnel shortage in the region by employing the graduates of educational institutions of higher education of Leningrad region is revealed. We offer guidelines for the development of educational programs offering additional professional training to ensure the competitiveness of graduates in digital economy and the development of the human resources potential of the region.
Procedure for Concluding an Agreement on Modification of Boundaries Between Constituent Entities of the Russian Federation
Authors: Шестаков Д.А.
Published: November 2023

В статье рассмотрена процедура заключения субъектами Российской Федерации соглашения об изменении территориальных границ. Рассматриваемая процедура проанализирована и охарактеризована в контексте теоретических и практических аспектов необходимости ее законодательного закрепления. По результатам исследования определены этапы, правила, принципы и особенности процедуры заключения соглашения об изменении территориальных границ субъектов.

The article describes the procedure of concluding and Agreement for modification of boundaries between constituent entities of the Russian Federation. The procedure under review has been analyzed and describes in the context of theoretical and practical aspects of the need for its legislative recognition. Based on the results of the study the article presents stages, rules, principles and specific features of the procedure of concluding an Agreement on changing the boundaries of constituent entities of the Russian Federation.
Perspective Ways of Research Development for New Information Technologies Used in Forensic Science
Authors: Бачиева А.В. , Макарова Е.Н.
Published: November 2023

В статье утверждается, что цифровизация всех сфер общества привела к резкому росту числа преступлений, совершенных с использованием информационных технологий. Современные информационные технологии показали необходимость новых путей развития и поиска новых способов обеспечения информационной безопасности, в том числе средств и методик выявления, раскрытия и расследования преступлений. Авторы обращают внимание на перспективы применения цифровой криминалистики для выявления цифровых следов и установления обстоятельств преступления.

The article claims that digitalization in all sectors of society has led to a sharp increase in the number of crimes committed with the use of information technologies. Modern information technologies showed the need for new ways of the development as well as for the search for new ways of ensuring information security, including tools and methods of identification, detection and investigation of crimes. The authors draw attention to perspectives of applying digital forensics for digital detection and identification of circumstances of crime.
On Differentiation of Invalidity of Deals under Art. 168, 169 of Civil Code of the Russian Federation
Authors: Кузбагаров Э.А.
Published: November 2023

Проблема недействительности сделок, согласно авторской позиции, является актуальной на протяжении длительного времени в цивилистике, в особенности по основаниям, предусмотренным ст. 168 и 169 Гражданского кодекса Российской Федерации (ГК РФ). Рассмотрение указанных гражданских правоотношений позволило автору статьи выявить особенность, характерную для российского законодательства и чуждую для порядка других стран. В отдельных из них такие сделки характеризуются как исключительно ничтожные. Разделение отечественным законодателем сделок на оспоримые и ничтожные обусловлено критерием нарушения публичного интереса и законных интересов третьих лиц, что требует разъяснения и вызывает необходимость его понимания. Кроме того, судебной практикой выработана совокупность применения ст. 10 и 168 ГК РФ, что создает альтернативу составу, предусмотренному ст. 169 ГК РФ, о признании сделки недействительной, во избежание применения санкции в виде обращения в доход государства полученного по недействительной сделке.

Under the author’s position the problematic issue of invalidity of transactions has been relevant for a long time in civil law, especially for reasons provided for in Art. 168 and Art. 169 of the Civil Code of the Russian Federation. The study of specified civil legal relations made it possible to identify a feature considered to be specific for the Russian legislation yet alien to order of other countries. In some of them such deals are considered to be void. The division of transactions into voidable and negligible by domestic lawmakers is caused by the criterion of breach of public interests and legitimate interests of thirds parties which requires further clarification and raises the need for its understanding. In addition, judicial practice has worked out a cumulative application of Art. 10 and 168 of the Civil Code of the Russian Federation, which makes it possible to create an alternative to the Art. 169 of the Civil Code of the Russian Federation to recognize the deal as invalid, in order to avoid the application of a sanction in the form of turning to the state revenue received under an invalid deal.
Assessment Indicators of Socio-Economic State of Agriculture (by the example of Omsk region)
Authors: Сергиенко О.В.
Published: November 2023

В статье обоснована стратегическая важность институциональной среды сельскохозяйственной отрасли, которая определяет ее специфику в области организационно-экономического механизма адаптации аграрного сектора к условиям новых качеств глобальной среды как социо-эколого-экономической системы. Социо-эколого-экономическая оценка устойчивости аграрного сектора экономики в разрезе трех критериев развития – социального, экономического и экологического как единого оценочного показателя позволит проводить экспресс-анализ и мониторинг через основные факторы и составляющие, учитывающие специфику аграрной отрасли как комплексной системы. Итоги мониторинга позволяют выявить совокупность критериев, определяющих вектор устойчивого развития агарной отрасли как основополагающего фактора развития сельских территорий.

We substantiate the strategic importance of the institutional environment of agricultural industry that determines its specific features concerning the organization and economic mechanism of the adaptation of agrarian sector to the new global environment as a socio-ecological-economic system. Social, ecological and economic assessment of sustainability of agrarian sector from the point of view of three development criteria, namely social, economic and ecological, as a single indicator enables to carry out express analysis as well as monitoring relying on key factors and components taking into consideration the specific features of agrarian industry as a complex system. The monitoring results help to distinguish a set of criteria determining the direction for sustainable development of the agrarian industry as the basic factor of rural territories development.
The All Russian Constituent Assembly as Part of Transitional State Legal System: Historical and Legal Analysis
Authors: Лясович Т.Г.
Published: November 2023

В статье представлен авторский анализ правового статуса Всероссийского Учредительного собрания, созванного в январе 1918 г., в системе органов государственной власти Российской республики, рассмотрены организационные мероприятия по подготовке и проведению избирательной кампании. Актуализации задачи исследования способствует, во-первых, сложность исследуемого исторического периода, его насыщенность глобальными с исторической точки зрения событиями и фактами; во-вторых, степень их влияния на отечественную правовую традицию и государственность; в-третьих, полярность оценок советских и российских ученых в отношении государственно-правовых трансформаций. Учредительное собрание рассмотрено автором как парламентский орган переходного типа, образование которого свидетельствует о состоянии «переходности» отечественной государственности анализируемого исторического периода.

The article presents the author's own analysis of the legal status of the All Russian Constituent Assembly convened in January 1918, in the system of the state power authorities of the Russian Republic with focusing on organizational arrangements related to preparation and conduct of the election campaign. The actualization of this research objective is contributed firstly by the complexity of the historical period under research and its richness of global facts and events in terms of historical point of view, secondly — by the degree of their influence on domestic legal tradition and statehood and finally — by the polarity of assessments of Soviet and Russian scientists with regard to state-legal transformations. The Constituent Assembly has been considered by the author to be a transitional parliamentary body, the foundation whereof attests to the state of transitivity of domestics statehood in historic period under analysis.
Methodological Approaches to Assessing Level of Innovative Development of Service Sector
Authors: Гродинская А.Н.
Published: November 2023

В статье рассмотрены и охарактеризованы основные методические подходы к оценке инновационного развития сферы услуг с позиции конкретного субъекта управления данным процессом. В качестве ключевых подходов с позиции проведения государственной политики в данной области автор выделяет следующие: унифицированный подход к оценке сферы услуг как части национальной экономики, отраслевой подход, региональный подход.

We consider and characterize the main methodological approaches to assessing the innovative development of the service sector from the standpoint of a particular subject of managing the process in question. The following approaches are distinguished as the key ones taking into consideration the state policy in this area: a unified approach to assessing the service sector as a part of the national economy, sectoral approach, regional approach.
sCIP-ing towards streamlined chemoproteomics
Authors: Burton Nikolas , M Backus Keriann
Published: November 2023

Mapping the ligandability or potential druggability of all proteins in the human proteome is a central goal of mass spectrometry-based chemoproteomics. Achieving this ambitious objective requires high throughput and high coverage sample preparation and LC-MS/MS analysis for hundreds to thousands of reactive compounds and chemical probes. Conducting chemoproteomic screens at this scale benefits from technical innovations that achieve increased sample throughput. Multiplexed analysis using commercially available amine-reactive isobaric reagents (e.g. tandem mass tags or TMT) is a favored strategy to decrease instrument acquisition time. These reagents are ideally suited for protein-based quantification applications, with efficient capping and pooling of peptides after sequence specific digestion. The added enrichment steps in nearly all chemoproteomic sample preparation workflows reveals a still largely untapped opportunity for isobaric labeling, namely incorporation of the TMT label into the chemoproteomic enrichment handle for early sample pooling and increased sample preparation throughput. Here we realize this vision by establishing the silane-based Cleavable Linkers for Isotopically-labeled Proteomics (sCIP)-TMT proteomic platform. sCIP-TMT pairs a custom click-compatible sCIP capture reagent that is readily functionalized in high yield with commercially available TMT tags. Synthesis and benchmarking of a 10-plex set of sCIP-TMT reveals a 1.5-fold decrease in sample preparation time together with high coverage and high accuracy quantification. By screening a focused library of cysteine-reactive electrophiles, we demonstrate the utility of sCIP-TMT for chemoproteomic target hunting, identifying 789 total liganded cysteines. Distinguished by its compatibility with established enrichment and quantification protocols, we expect sCIP-TMT will readily translate to a wide range of chemoproteomic applications.
Computational Discovery of Codoped Single-Atom Catalysts for Methane-to-Methanol Conversion
Authors: Jia Haojun , Duan Chenru , Kevlishvili Ilia , Nandy Aditya , Liu Mingjie , Kulik Heather
Published: November 2023

The absence of a synthetic catalyst that can selectively oxidize methane to methanol motivates extensive study of single-site catalysts that possess a high degree of tunability in their coordination environments and share similarities with natural enzymes that can catalyze this reaction. Single-atom catalysts (SACs), and in particular doped graphitic SACs, have emerged as a promising family of materials due to their high atom economy and scalability, but SACs have yet to be exhaustively screened for methane-to-methanol conversion. Modulating the coordination environment near single metal sites by means of codopants, we carry out a large-scale high-throughput virtual screen of 2,048 transition metal (i.e., Mn, Fe, Co, and Ru) SACs codoped with various elements (i.e, N, O, P and S) in numerous spin and oxidation (i.e., M(II)/M(III)) states for the challenging conversion of methane to methanol. We identify that ground state preference is metal- and oxidation-state dependent. We observe a weak negative correlation between the oxo formation energy (ΔE(oxo)) and the energy of hydrogen atom transfer (ΔE(HAT)) thanks to the high variation of the coordination environment. Therefore, codoped SACs demonstrate flexible tunability that disrupts linear free energy relationships in a similar manner to homogeneous catalysts without losing the high scalability of heterogeneous catalysts. We identify energetically favorable catalyst candidates along the Pareto frontier of ΔE(oxo) and ΔE(HAT). Further kinetic analysis reveals an intermediate-spin Fe(II) SAC and a low-spin Ru(II) SAC as promising candidates that merit further experimental exploration.
Theoretical and Experimental Study of the Distribution of Capacitive Times
Authors: Py Baptiste , Maradesa Adeleke , Ciucci Francesco
Published: November 2023

The distribution of relaxation times (DRT) method is a non-parametric approach for analyzing electrochemical impedance spectroscopy (EIS) data. However, we must be careful when using the DRT method on electrochemical systems with blocking electrodes, such as those encountered in batteries and supercapacitors. This is because at low frequencies the asymptotic behavior of the DRT model cannot capture unbounded impedances. To address this issue, we explore the distribution of capacitive times (DCT), a method that, despite being developed decades ago, is still not widely used. In this work, we detail the theoretical underpinnings of the DCT, deriving DCT-specific analytical formulae based on several standard impedance models. We also draw parallels between DCT and DRT and show how these two methods differ in capturing timescales and peaks, elucidating the scenarios where DCT can serve as a viable alternative should the DRT not be applicable. This article seeks to expand the scope of nonparametric approaches for EIS data analysis, particularly to systems characterized by blocking electrodes.