bluuebunny/crossref_metadata_2025 huggingface dataset:
Estymatory odporne zmienności w modelu wyceny Blacka-Scholesa
Authors: Majewska Justyna
Published: January 2024

Najważniejszym etapem przy wycenie opcji jest właściwe oszacowanie zmienności instrumentu finansowego. W przypadku występowania w zbiorze danych finansowych obserwacji odstających oraz grubych ogonów w rozkładzie danych zastosowanie znajdują odporne estymatory. W pracy przedstawione zostały odporne estymatory zmienności: t-estymatory oraz Aestymatory pozwalające na dokładniejsze wyznaczenie parametru zmienności. Dokonaliśmy analizy porównawczej wartości opcji na indeks WIG20 WGPW biorąc pod uwagę klasyczne odchylenie standardowe, odchylenie medianowe MAD, Aestymator oraz t-estymator. Wartości opcji zostały wyznaczone za pomocą powszechnie stosowanego przez inwestorów modelu wyceny europejskiej opcji kupna Blacka-Scholesa. Ponadto, w pracy przedstawiliśmy narzędzia modelowania odpornego do wykrywania obserwacji wpływowych i nietypowych oraz do analizy wpływu odporności estymatorów na pewne odstępstwa od założonego modelu
Analiza zmian kursu euro/dolara: model VAR i perceptron wielowarstwowy
Authors: Matuszewska Aleksandra , Witkowska Dorota
Published: January 2024

W analizach finansowych szeregów czasowych stosuje się często metody wielowymiarowego opisu zjawisk, takie jak na przykład modele wektorowej autoregresji (VAR). Alternatywnym do modeli VAR narzędziem badania mogą być jednokierunkowe sztuczne sieci neuronowe, do których należy perceptron wielowarstwowy (MLP). W pracy przedstawiono rezultaty wykorzystania modeli VAR i MLP do opisu zmian w szeregu kursu euro/dolar oraz tych zmiennych z rynku finansowego, które wpływają na badany kurs oraz ulegają zmianom pod wpływem kursu. Efektywność obu metod oceniono na podstawie dokładności wyznaczonych prognoz
Prognoza liczby emitowanych kart płatniczych
Authors: Adamczyk Marcin , Parlińska Maria
Published: January 2024

Wraz z rozwojem nowoczesnych technologii informacyjnych zrodziły się koncepcje społeczeństwa informacyjnego. Mimo, że nie jest to pojęcie jednoznaczne, wiele krajów, także Unia Europejska, uznały budowę społeczeństwa informacyjnego za priorytetowy cel. Zwiększona podaż informacji i wzrost możliwości wzajemnego komunikowania się w społeczeństwie i w gospodarce doprowadziły do znaczących zmian w zasadach prowadzenia biznesu. Banki znakomicie wykorzystały możliwości związane z rozwojem Internetu i gospodarki sieciowej. Inwestując duże środki i dostosowując swoje strategie marketingowe do nowych realiów zaoferowały klientom usługi bankowości elektronicznej, w tym bankowości internetowej, umożliwiając im zarządzanie swoimi finansami przez całą dobę, siedem dni w tygodniu z dowolnego miejsca na świecie. W artykule przeprowadzono analizę wybranego produktu bankowości internetowej - karty wirtualnej w kontekście tradycyjnych kart płatniczych z prognozą na najbliższe dwa kwartały
Przewagi komparatywne a wymiana handlowa produktami rolnymi krajów UE
Authors: Strojny Jacek
Published: January 2024

Niniejsze badanie koncentruje się na konkurencyjności rolnictwa krajów wchodzących w skład obszaru gospodarczego UE. Założeniem analizy jest, że niezależnie od źródła przewagi komparatywnej w danej dziedzinie ostatecznie znajduje ona odbicie w wymianie handlowej z innymi krajami. Konkurencyjność uwidacznia się poprzez specjalizację produkcyjną
Ekonometryczne modelowanie wybranych wskaźników makroekonomicznych w Polsce
Authors: Śliwicki Dominik
Published: January 2024

W opracowaniu został zaprezentowany przykład ekonometrycznego modelowania wybranych wskaźników makroekonomicznych z użyciem zgodnego dynamicznego modelu ekonometrycznego. Na podstawie oszacowanego modelu zostały wyznaczone prognozy na I kwartał 2006 roku oraz mnożniki bezpośrednie i pośrednie
Zastosowanie modelu MOTAD do tworzenia portfela akcji
Authors: Wisiński Krzysztof
Published: January 2024

W artykule omówiono metodologię modelu MOTAD pod kątem zastosowania tej metody do tworzenia portfela akcji. Praktyczne wykorzystanie zaprezentowanej metody zilustrowano przykładem empirycznym
Zastosowanie testu Perrona do badania punktów zwrotnych indeksów giełdowych: WIG, WIG20, MIDWIG i TechWig
Authors: Witkowska Dorota , Gasek Anna
Published: January 2024

Celem pracy jest identyfikacja zmian w strukturze trendu dla indeksów WIG, WIG20, MIDWIG oraz TechWIG w okresie od 1.07.2003 – 31.03.2006. Pierwszy etap badań polega na określeniu, za pomocą testu Perrona, momentu wystąpienia punktów zwrotnych. Drugi to ustalenie przyczyn pojawienia się istotnych zmian w analizowanym szeregu czasowym
Porównanie metod Tramo-Seats i Sieci Neuronowych wykorzystywanych do prognozowania krótkookresowego szeregów czasowych
Authors: Ząbkowski Tomasz
Published: January 2024

Artykuł prezentuje dwa podejścia prognozowania szeregu czasowego wykorzystania minut przez abonentów firmy telekomunikacyjnej. Do porównania zostały wykorzystane: metoda Tramo- Seats bazująca na metodologii ARIMA oraz różnego typu sztuczne sieci neuronowe. Metody te zostały w artykule gruntownie scharakteryzowane. Otrzymane w części eksperymentalnej wyniki dla prognoz krótkookresowych sugerują zasadność stosowania metody Tramo-Seats
Does emotional distress predict worse glycemic control over time? Results from the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study
Authors: Cherrington Andrea L , Bebu Ionut , Krause-Steinrauf Heidi , Hoogendoorn Claire J. , Crespo-Ramos Gladys , Presley Caroline , Naik Aanand D. , Balasubramanyam Ashok , R Gramzinski Michaela , Killean Tina , L Arends Valerie , Gonzalez Jeffrey S.
Published: January 2024

Objectives To evaluate whether baseline levels of depressive symptoms and diabetes specific distress are associated with glycemic control in the GRADE study, a large randomized controlled trial comparing the metabolic effects of four common glucose-lowering medications when combined with metformin in individuals with type 2 diabetes.

Methods The primary and secondary outcomes were defined as an HbA1c value ≥7%, subsequently confirmed, and an HbA1c value ˃7.5%, subsequently confirmed, respectively. Separate Cox proportional hazards models assessed the association between baseline levels of each exposure of interest (depressive symptoms measured by Patient Health Questionnaire (PHQ-8) and diabetes distress measured by Diabetes Distress Scale) and the subsequent risk of metabolic outcome.

Results This substudy included 1,739 participants (56% Non-Hispanic White, 18% Non-Hispanic Black, 17% Hispanic, 68% male, mean [SD] age=58.0 [10.2] years, diabetes duration=4.2 [2.8] years, and HbA1c=7.5% [0.48]). A total of 1,157 participants reached the primary outcome, with time to event of 2.1 years on average, while 738 participants reached the secondary outcome at 3 years on average. Adjusting for sex, race/ethnicity, treatment group, and baseline age, duration of type 2 diabetes, body mass index, and HbA1c, there were no significant associations between the depressive symptoms or diabetes distress and the subsequent risk of the primary or secondary outcomes.

Conclusions The current findings suggest that, at least at for individuals with diabetes of relatively short duration, baseline levels of emotional distress are not associated with glycemic control over time.
Did We Forget about Social Determinants of Health in Dermatology?
Authors: Christensen Elisabeth M.M. , Jemec Gregor B.E.
Published: January 2024

Abstract is missing (Editorial)
Writing in international journals is getting easier
Authors: Stam Henk , Borg Kristian
Published: January 2024

Abstract missing (Editorial)
Revolutionizing the Future: Exploring the Multifaceted Advances of Robotic Technologies
Authors: R Jain
Published: January 2024

In recent years, the realm of robotics has witnessed a remarkable evolution, transforming from rudimentary machines into highly sophisticated systems that are reshaping various aspects of our lives. This research paper delves into the multifaceted advances of robotic technologies, encompassing their applications in industries, healthcare, space exploration, and everyday life. Through a comprehensive review of the literature, we analyse the current state of robotics; discuss key achievements, challenges, and future prospects. This paper aims to provide an insightful overview of the burgeoning field of robotics, shedding light on its transformative potential.
Exception Handling in Logic Programming
Authors: K Kwon
Published: January 2024

One problem on logic programming is to express exception handling. We argue that this problem can be solved by adopting linear logic and prioritized-choice disjunctive goal formulas (PCD) of the form G G 0 *1 ⊕ where G0, G1 are goals. These goals have the following intended semantics: sequentially choose the first true goal GI and execute GI where i (= 0 or 1), discarding the rest if any.
Phytochemical Screening of Ficus benjamina (Linn.) Fruit Extracts
Authors: KS Bora
Published: January 2024

Ficus benjamina (Linn.) commonly called as weeping fig, is distributed throughout forests of eastern Himalayas of India, Fego, Travancore and Archipelago and China. It is useful in inflammation, syphilis, dysentery, erysipelas and as general tonic. Traditionally, fruit extract of Ficus benjamina has been used in skin disorders, inflammation, piles, leprosy, malaria, cancer, ulcer and as insect repellant. Detection, quantitative and qualitative determination of different classes of phyto-constituents present in any plant is considered important parameters which give an indication of the therapeutically active constituent(s) present in the plant. An extensive literature survey on Ficus benjamina showed that sporadic phytochemical reports are available. Therefore, it was considered worthwhile to perform phytochemical screening of various fruit extracts of Ficus benjamina which was not evaluated till date. Therefore, the present investigation was planned to investigate phytochemical screening of Ficus benjamina fruit extracts. Various extracts were prepared using successive Soxhlet extraction method. Solvents viz. petroleum ether, chloroform, ethyl acetate, ethanol and water in increasing polarity order were used to prepare extracts. Results of the present study showed that ethanol and ethyl acetate extract showed bioactive phytoconstituents like flavonoids, phenolic compounds and coumarins which could be responsible for various biological activities of Ficus benjamina.
Medicinal Plants used by Traditional Healers in Lohagara Upazila of Narail District, Bangladesh
Authors: AHMM Rahman
Published: January 2024

Medicinal plants used by traditional healers in Lohagara Upazila of Narail district, Bangladesh was recorded from November 2018 to March 2020. The present paper deals with traditional uses of 101 medicinal plant species 89 genera and 55 families along with correct botanical identification. Semi-structured interviewees, observation and guided field walk with informants were employed to obtain medicinal data in the study area. In the area, a total of 73 human diseases were recorded and treated with various plant species and preparations. For each species, scientific name, local name, family, habit, diseases, mode of administration and part(s) used are provided. The study aims to bring awareness among the people, to save this precious knowledge and protect these plants, for the next generation.
Management of Deep Vein Thrombosis with Raktamokshana: Single Case Study
Authors: D Aswal
Published: January 2024

Deep vein thrombosis (DVT) is the formation of blood clots (thrombi) in the deep veins. It commonly affects the deep leg veins (such as the calf veins, femoral vein, or popliteal vein) or the deep veins of the pelvis. It is a potentially dangerous condition that can lead to preventable morbidity and mortality. This case is about a 35 year-old male who was found to have partial deep vein thrombosis in the left femoro popliteal venous system detected on a doppler previously ordered for work-up of leg pain after diagnosis of pulmonary embolism. Patient has been suffering from pain swelling, discoloration in the left leg since 3 years. He had no prior risk factor, personal or familial history of venous thrombosis. He underwent conservative treatment for his complaints but got no significant relief and condition further aggravated. So for the management he came to Out Patient Department of Panchakarma, Rishikul Ayurvedic College Hospital where eight sittings of Jalaukavacharan (leech therapy) was done. After 8 sittings, he got significant relief in his problems; his daily activities and quality of life also improved.
Role of Panchakarma in the Management of COVID-19
Authors: B Beena
Published: January 2024

Panchakarma is a branch of Ayurveda medicine that deals with both purification and palliative aspect. Covid 19 is a pandemic disease of recent outbreak affecting almost all age group people worldwide. Allopathic medicine is doing at its best to fight with severity as well as mortality of Covid 19. However, we can strengthen the current treatment protocol of Covid 19 by integrating Ayurveda and Panchakarma measures into it. Depending upon the severity, stages of the diseases as well as associated comorbidities, we have to advocate different Panchakarma therapy like Kavala, Nasya, Virechana etc. Panchakarma has great role in case of prevention and management of Covid 19 cases right from home isolation patients to patients managed in I.C.U. setup.
A Protocol of Assessing Ras Dosha Prabhav of Ayurvedic Medicine on Kapha Vruddhi Lakshan
Authors: B Mhaiskar
Published: January 2024

Healthy and unhealthy state of a person's being depends on normal and abnormal functional state of Tridosha, considering the physiological importance of Dosha in maintenance of homeostasis of the body they also are called as roots of the body. All the functions of the body might be explained in terms of Dosha, Dhatu and Mala. Tridosha are the biological entities derived from Panchamahabhuta, liable for regulation of all bodily functions and its regulation. Variations in functional state of Tridosha with reference to age, day-night, and season occurs to accommodate body with the environmental influences like sunrise, sunset and differences due to the season. Ayurveda has described three dynamic states of Tridosha, namely Sama (balanced state). This paper is aimed to summarize and analyze the descriptions regarding the hypo and hyper functional states of Tridosha (Dosha Kshya-Vriddhi) made by Ayurvedic scholars and suggest some objective parameters to assess the functional state of Tridosha. Aim of study is Evalution of the Concept Of Ras-dosha sambandh siddhant by Using Kaphshamak Ras (Katu, Tikta, Kashay) Dravyas In Kaphvruddhi Lakshanani. Study Design is seven arm comparative clinical study, Study Type is Interventional study Sample size is 420 Subjects (60 in each group) Sample selection techniques: Selections of subjects will be done by lottery method. Subjects in the age group of 16-50 years of irrespective sex having cardinal features of kaphavruddhi lakshan Agni sadan, Prasek, Alasya, Gaurav, Shvaithya (white discoloration),Shaithya (coldness), Shlathangatva (looseness of the body parts), Shwasa (dyspnoea), Kasa (cough, cold), Atinidrata (excess of sleep. 7-7½ hrs). • Criteria for Selection of Subjects: Subjects with signs and symptoms of Kaphvruddhi Lakshanani will be selected from OPD Deptartment of Swasha rakshan (MIMS Sumati bhai Shah Ayurved Mahavidyalaya, Pune). Approval of the study will be taken after presentation from institute’s ethics committee The cases will be enrolled after describing the treatment and obtaining informed consent in English and local language. Subjects eligible for inclusion criterion who will be selected for clinical trial, drugs are Standardized and well authenticated chitrak, patala, bhibhitaka will be procured from market. Interventional trial will be measured and by proper statistical analysis the observations of parameters are assessed.
To Know the Efficacy of Shirodhara with Ksheerbala Taila in Anidra W.S.R to Insomnia: Single Case Study
Authors: M Bharti
Published: January 2024

Ayurveda has given more importance to Nidra by considering it as one among the Trayo Upasthambha. The disturbance to Nidra includes Anidra which is said to be a Vata Nanatmaja Vyadhi That can be correlated to insomnia. In Anidra both vata and Manas play an important role. Hence Acharyas gave importance to Vata in the management of Anidra with Murdhni Taila. Ksheerbala Taila which is used here is having Vatashamaka and Brimhaniya Properity thus it enchances the Pusthi of Dhatus and thus acts on Anidra. Here is a Case study to evaluate the efficacy of Shirodhara with Ksheerbala Taila in Anidra. A 37year female patient with the history of Anidra, Krodh. Shoka, Ajirn, Katishoola, since 25 year. She came Panchkarma O.P.D of Rishikul campus Uttarakhand Ayurved University Haridwar, for treatment. The patient was Vata pitta Prakriti with no systemic history of any systemic disease. She was planned for Management with Shirodhara with Ksheerbala taila and Ayurvedic internal medicine Avipattikar Churna and she got moderated relief in sleep pattern.
Preliminary Finding: Survey on Eating Disorder and Nutritional Status among Young Athletes
Authors: CPF Wong
Published: January 2024

Introduction: It is well documented that eating disorders will have a negative impact on health status and athletic performance. The risks of eating disorders among athletes are required to be detected early before it affects athlete’s health and exercise performance. To date, there is still scanty information on eating disorder and nutritional status among young athletes in Sabah. Objective: The objective of this study was to determine eating disorders and nutritional status among young athletes in Sabah. Methodology: A total of 55 young athletes who are active representatives of sports competitions were selected to participate in this study. Eating attitudes test questionnaires (EAT-26) was used to determine eating disorder risk. International physical activity questionnaire (IPAQ) and 3-days food diary were used to determine nutritional status and physical activity level. Statistical Package for the Social Sciences (SPSS) version 27.0 was used to analyse the collected data. Pair-t test was used to compare energy intake of subjects with the recommended nutrient intake for Malaysia (PAL2.0). The significant level is p<0.05. Results: This study found that aesthetic and weight category sports were the highest risk for eating disorder. Energy intake (kcal/day) in the aesthetic, weight category, endurance and ball games did not significantly meet the daily energy intake recommendations. Conclusion: As a conclusion, majority of the subjects did not practicing balanced diet and meet the recommended nutrient intake (RNI) especially in the aesthetic and weight category sports. These current findings are useful to detect early eating disorder among young athletes before it become critical and affect athletes’ exercise performance and health status.
Ayurvedic Literature Review of Vataja Pratishyaya WSR Allergic Rhinitis
Authors: B Beena
Published: January 2024

The basic life of a human is dependent on air and water but the natural sources also serve as the source of infection. Due to modern civilization, there is increasing evidence of the negative health impact resulting from environmental air pollutants. Ayurveda science mentioned air pollutants like Raja, Dhooma as causative factors of respiratory illness including Allergic Bronchitis (Shwasa), Allergic rhinitis (Pratishyaya), Cough (Kasa) and Hiccough (Hikka). Vataja pratishyaya/Allergic rhinitis occurs much more frequently than before. Pratishyaya has been considered as a separate clinical condition in Uttar tantra of Sushruta Samhita. Allergic rhinitis can be correlated with the Vataja Pratishyaya due to similarities in the sign and symptoms. Allergic rhinitis is an inflammation of nasal membranes, characterized by watery nasal discharged, nasal obstruction, sneezing and nasal itching. Many treatment modalities are explained in modern system of medicine like corticosteroids, antihistaminic, inhalers etc. but none of them are totally effective in curing the disease as well as preventing its recurrence, more over they have their own side effects.
Endometriosis Mimicking Ovarian Malignancy: Diagnostic Dilemma of Three Cases
Authors: Thakur Brijesh
Published: January 2024

Ovarian endometriosis is an estrogen dependent gynecologic disease commonly affecting reproductive age group and 2-5% of postmenopausal women. Widespread endometriosis may be misdiagnosed as metastatic ovarian malignancy by imaging especially when coupled with increased levels of CA125. Present study reviews three such cases highlighting the need for high index of clinical suspicion in the correct case scenario. The clinicians should be aware of this mimicker as misdiagnosis has potential to distort the course of disease and may lead to unnecessary radical surgery in patients.
Sonographic Evaluation of Normal Placenta Thickness among Apparently Healthy Women in Second and Third Trimester Pregnancy
Authors: Kalu Ochie
Published: January 2024

Some maternal fetal disorders can be detected or revealed for further investigation from data obtained from the placenta thickness. Suboptimal placenta thickness or enlarged placenta may be a pointer to disorder such as anaemia, hypertension or diabetes, growth retardation among others. Small placenta is associated with malnutrition and increased risk of chronic disease later in life. The aim of this study is to determine the normal thickness of placenta in Nigeria. Any placenta thickness outside this value should be further investigated for possible maternal or fetal anomalies. Four hundred subjects were selected by convenience sampling after passing the inclusion criteria, and educational status required. The abdomen of pregnant women with gestational age of 16 to 40 weeks referred from antennal clinic and who gave consent to participate in the study were scanned. The scan ruled out abnormalities and measured the gestational age using fermur length (FL) and Biparetal Diameter (BPD) to compare with menstrual gestational age (MGA). The placenta thickness was measured at the thickest point of the umbilical cord insertion into the placenta. Result showed that placenta thickness for GA of 16 to 40 weeks was from 15 to 39mm (SD: 5.62). The study suggests that pregnancy with placenta thickness outside this predictive thickness should be subjected to further investigation to rule out maternal or fetal abnormalities associated with enlarged placenta or subnormal placenta thickness.
Female Genital Cutting or Circumcision
Authors: Haider Rehan
Published: January 2024

Woman genital slicing additionally referred to as woman genital mutilation or circumcision, is a deeply rooted cultural exercise that entails the partial or overall elimination of outside lady genitalia for non-scientific reasons. Despite being extensively criticized for its bodily and psychological fitness dangers, as well as its violation of human rights, the practice persists in various parts of the sector, specifically in Africa, the Middle East, and Asia. Female genital reduction is regularly justified inside communities as a ceremony of passage, a method of maintaining purity, or a way to control ladies’ sexuality. However, its effects are long-lasting and negative. The system can result in severe pain, bleeding, infections, and long-term period complications, which include urinary issues, headaches throughout childbirth, and mental trauma. The ethical issues surrounding this practice are obtrusive, as it infringes upon physical autonomy, sexual well-being, and gender equality. Efforts to eliminate female genital slicing span scientific, legal, and social dimensions. Several worldwide groups and governments have denounced the practice and enacted legal guidelines against it, specializing in cognizance campaigns, education, and community engagement. Grassroots projects inside affected groups have proven effective in transferring perceptions and hardening the deeply ingrained beliefs that perpetuate the exercise. To put off lady genital slicing, a holistic method is vital-one that includes not only the best criminal measures but also complete sex schooling, female empowerment, and collaboration with cultural and religious leaders. By addressing the underlying social norms and offering alternative cultural practices, societies can safeguard the rights and fitness of girls and women, letting them lead lives free from the bodily and emotional burdens of female genital reduction.
Childhood Sexual Abuse is the Root Cause for Panic Attack
Authors: Banik Monica
Published: January 2024

Childhood sexual abuse is not rare anymore. People don’t talk about it often, but it is there. Specifying any gender would be wrong, but almost 96% of children are sexually abused in the entire world. Most of them are abused by their own relatives or close neighbours. Sometimes even by their own parents and siblings
Assessing the Effectiveness of Lateral and Semi Fowler’s Position on Selected Patients Admitted with Respiratory Problems in Different Hospitals
Authors: Prajapati Archna
Published: January 2024

Introduction: Respiratory disease is a medical term that encompasses pathological conditions affecting the organs and tissues that make gas exchange possible in higher organisms and includes conditions of the upper respiratory tract, trachea, bronchi, bronchioles, alveoli, pleura, pleural cavity, the nerves and muscles of breathing. Positioning is one of the most frequently performed nursing activity in the critical care, often providing a central pivotal focus for planning other nursing activity. Lateral position involves the patient lying on either patient’s right or left side. Semi Fowler’s Position is a position in which a patient is positioned on their back with the head and trunk raise to 30 degrees. So, the main objective of this study was to compare and evaluate the effectiveness after giving Lateral position in group 1 & Semi Fowler’s position in group 2 among patients admitted with Respiratory problems. Method: A comparative study was conducted to assess the effectiveness of Lateral position v/s Semi Fowler’s position on selected Respiratory Parameters among the patients admitted with Respiratory problems for which 40 samples were selected by non-random purposive sampling and the data was collected by assessing the selected respiratory parameters (blood pressure, oxygen saturation, breath holding time, respiration rate & heart rate) using instruments. Quantitative Research Approach was used in this study and research design was Quasi Experimental Research Design. The collected data was analyzed by Descriptive and Inferential Statistics. Result: Majority of the patients are male as compared to female and above 51 years of age. On the basis of comparing the posttest mean values of both the group, the posttest mean value (417.05) of group 2 (Semi Fowler’s position) is much higher than the posttest mean value (403.1) of group 1 (Lateral position). The result revealed that both the positions are effective to improve the respiratory parameters but on the basis of mean post test score the semi fowler’s position is more effective when compared to lateral position on respiratory parameters. The t value is found to be 3.022 with the significance level of p<0007. Therefore, Hypothesis H3 is accepted. Conclusion: From the finding of the study, the respiratory parameters were improved in semi fowler’s position as compared to lateral position. Paired ‘t’ value was significantly higher where p value is <0.05. Thus, it is concluded that the Semi Fowler’s position is highly effective to improve the selected Respiratory Parameters on the patients admitted with Respiratory Problems.
Brain Tuberculoma Presenting as Cerebral Cystic Tumor
Authors: Riahi Anis
Published: January 2024

Etiological diagnosis of cystic tumor in adult patients can be laborious. Differential diagnosis includes a variety of primary brain tumors such as pilocytic astrocytomas and gongliogliomas, metastases or brain abscesses. We report herein an exceptional cause of cystic brain tumor in a 22-year-old Tunisian man. The patient presented with acute intracranial hypertension syndrome with a right temporal parenchymatous cystic mass on brain MRI. This mass has a nodule of 25 mm in contact of its posterior wall, taking intense and homogenous contrast after Gadolinium injection, and associated with perilesionel edema. Operative findings denoted that cystic component of the tumor was in fact the temporalhorn of the lateral ventricle that has been excluded by the nodular lesion. Pathological study of the nodule confirmed the diagnosis of brain tuberculoma. In endemic area; tuberculosis must be ruled out first in patients with braintumors since it may simulate any type of lesion.
Climate Change and Animal Health Impacts Challenges and Mitigation Strategies
Authors: Jain Rahul
Published: January 2024

Climate change has emerged as one of the most pressing global challenges, exerting profound impacts on both human societies and animal populations across a wide array of ecosystems. This mini review paper delves into the multifaceted and far-reaching consequences of climate change on animal health, shedding light on the complexities faced by various species as they grapple with the rapidly changing environmental conditions. From polar bears in the Arctic to coral reefs in the oceans, animals are experiencing disruptions in their natural habitats due to rising temperatures, altered precipitation patterns, and extreme weather events. These changes, in turn, affect their physiology, behavior, and overall well-being. One of the key challenges lies in the ability of animals to adapt to these swift alterations in their surroundings. While some species demonstrate remarkable resilience and adaptability, others face the risk of extinction, unable to cope with the changing climatic conditions. This review explores the diverse impacts of climate change on animal health, considering not only charismatic megafauna but also often overlooked species crucial to ecosystem stability, such as insects, amphibians, and marine life. It delves into the intricate interconnections between climate change and disease prevalence among animals, highlighting the emergence and spread of new pathogens in response to altered environmental factors. Furthermore, the paper investigates the cascading effects of climate change on animal behavior, including migration patterns, mating rituals, and feeding habits, which ultimately influence ecosystem dynamics. Recognizing the urgent need for action, this paper also proposes a range of innovative and practical mitigation strategies aimed at safeguarding the well-being of diverse animal species. These strategies encompass habitat conservation, sustainable wildlife management, captive breeding and reintroduction programs, and the implementation of climate-resilient corridors to facilitate species movement. Additionally, the review emphasizes the importance of international collaboration, policy interventions, and public awareness campaigns in mitigating the adverse effects of climate change on animal populations. This mini review provides a comprehensive overview of the challenges posed by climate change to animal health, emphasizing the need for proactive measures to protect the rich biodiversity of our planet. By understanding the intricacies of these challenges and implementing effective mitigation strategies, society can work towards ensuring the survival and flourishing of diverse animal species in the face of ongoing climate change.
Revolutionizing Drug Delivery: Targeted Approaches and Innovations for Effective Treatment
Authors: Haq M Misbah Ul
Published: January 2024

Targeted drug delivery, also referred to as intelligent drug delivery, is a therapeutic approach that aims to enhance drug concentration in specific regions of the body relative to others. There are two strategies employed to target drugs to specific organs or tissues: passive targeting and active targeting. Drug delivery vehicles are utilized to transport the medication to the desired location. An ideal drug delivery vehicle should have the ability to overcome barriers such as the blood-brain barrier. Conventional drug delivery systems distribute drugs throughout the body via the bloodstream, resulting in only a small fraction of the drug reaching the affected organ. Smart drug delivery focuses on delivering the drug to the absorption site while minimizing its distribution in other tissues. This approach enhances effectiveness and reduces side effects by evading the body’s defense mechanisms and non-specific distribution. When designing a targeted drug delivery system, various factors such as drug characteristics, side effects, administration route, target site, and the specific disease must be taken into consideration.
Study of Medicine E-Trade Regulation in Senegal
Authors: Y Ndao
Published: January 2024

Introduction: E-trade covers, in addition to online selling activities, services relating to internet use. Several European states already authorize medicines e-trade, with or without prescription. In Senegal, fake drugs online sale in violation of pharmaceutical monopoly has provoked many debates, both among health professionals and patients. The objective of our work is to contribute to development of medicine e-trade regulation in Senegal. Methodology: It’s a retrospective and cross-sectional study, carried out from October 1st, 2018 to July 31th, 2019, using a documentary review and interviews. Data were compared with those of the literature. Results: There is a significant institutional mechanism marked by establishment of structures and/or control of e-trade. At legal level, law on electronic transactions and its implementing decree encourage exercise of e-trade activity. Violations of rights of person with regard to processing of personal data are sanctioned. However, technical service provider has an obligation to inform consumer, who may apply withdrawal right, due to unavailability of goods or services ordered. As for drug trade, practice of pharmacy is well supervised. Monopoly of medicine sale is reserved for pharmacists, who must exercise their activity in a licensed pharmacy. However, medicines e-trade falling within same logic, and coming under full responsibility of pharmacist, is not taken into account by our current law on pharmacy. However, law on electronic transactions creates conditions for medicines e-trade exercise. Conclusion: In Senegal, medicines e-trade does not have any specific regulations. However, law on e-trade has set up conditions for exercising medicine e-trade
Formulation and Quality Evaluation of Banana Wine
Authors: L Potey
Published: January 2024

Fruits are very often used for the wine preparation since the beginning of civilization. In recent years emphasis has been given to fruits such as banana for the preparation of wine. Banana is highly perishable in nature, the fermentation is a low energy prevention process to increase a shelf life of this fruits. Banana has good amount of sugar content that makes them suitable substrate for the preparation of wine. The fermenting for analysis of pH, titrable acidity, specific gravity and reducing sugar using standard fermentation of banana wine lasted for 7 days. Physico-chemical parameters were determined during fermentation using standard procedures. Liquor of the fermenting must remove from every 48 hours from standard procedures. The effects showed that specific gravity of the wine used to be discovered to reduced notably as the fermentation progressed. The pH of banana wine at some point of fermentation improved from 3.80 to 4.16 at day to the closing day while the titrable acidity. (% w/v tartaric acid) of the banana wine reduced make bigger from 1.05 to 1.77. The alcohol content of the wine multiplied with time. This work has been focused on formulation and evaluation of banana wine in college laboratory
Current Trends in Planning, Preparation and Delivering Regulatory Submissions in India & USA
Authors: N Mounika
Published: January 2024

The drug markets on the planet have various prerequisites for the enrolment of a drug item. To fit the prerequisites according to the administrative organizations, an idea of basic specialized report was actualized by ICH. Getting ready administrative entries in the drug business can be an extremely upsetting encounter because of the enormous measure of work and the need to explore and comprehend administrative accommodation necessities. This paper means to help administrative experts by giving data and exhortation to arranging and setting up an administrative accommodation. The paper centres around the conveyance of accommodation information bundles, since these are commonly the duty of administrative experts. The paper will cover the Regulatory necessities for entries, Components of accommodation information bundles, arranging an accommodation and best practices for getting ready accommodation information bundles.
Understanding Glomangiopericytoma: A Case Report of a Rare Sinonasal Tumor
Authors: A Chathamvelli
Published: January 2024

Introduction: Glomangiopericytoma (GPC) is a benign neoplasm of the sinonasal tract that consists of spindle-shaped to ovoid cells with lobular or nodular growth patterns. GPCs are low-malignant tumors due to limited mitotic activity and atypia, making them less aggressive. The etiology of GPC remains unknown but is associated with factors like steroid use, past trauma, pregnancy, and hypertension. GPC is more common in women and is usually diagnosed in the sixth and seventh decades of life. Case Presentation: This article presents a case of a 47-year-old woman with a history of type-2 diabetes and nasal obstruction who was diagnosed with glomangiopericytoma (GPC), a rare sinonasal tumor. Computed tomography revealed a vascular mass, and complete surgical resection was achieved via a trans-nasal approach. The diagnosis was confirmed through positive β-catenin staining and negative S100p and STAT6 with a low Ki67 proliferation index. The patient experienced post-operative pain, anosmia, and ageusia, which were treated successfully. This case highlights the clinicopathologic characteristics, clinical and therapeutic aspects, surgical interventions, and differential diagnosis of GPC, a rare disease with limited reports. Conclusion: Glomangiopericytomas are benign sinonasal tumors often mistaken for other neoplasms. Diagnosis is challenging but possible through excision or biopsy with histopathological examination. Endoscopic surgery with follow-up is the recommended treatment, with recurrence occurring up to 12 years post-surgery. CTNNB1 gene mutations and β-catenin nuclear expression are recent diagnostic markers. GPC has a high survival rate and low metastasis, but patients should be closely monitored. This case report underscores the importance of comprehensive diagnosis and management for these rare tumors.
Advances in the Preparation Techniques of Floating Microspheres with Exploration of AI Tool in Product Development
Authors: DA Bansode
Published: January 2024

This review paper focuses on recent developments in gastroretentive drug delivery systems for controlled release oral drug administration. Gastric emptying’s variability presents challenges to drug delivery systems, making gastroretentive drug delivery systems increasingly popular for retaining drugs in the stomach and ensuring gradual release. Traditional oral delivery systems often fail to overcome gastrointestinal obstacles, resulting in incomplete drug release, decreased efficacy. Thus, achieving prolonged gastric residence times is crucial, particularly for drugs with upper small intestine absorption windows. Gastro retentive drug delivery system provide for prolonged drug release in the upper digestive system, improving bioavailability for drugs with narrow therapeutic windows, extending dosing intervals, and enhancing patient compliance. The purpose of this review is to discuss recent advancements in the preparation techniques for floating drug delivery systems and highlights the incorporation of AI-Enabled design and optimization in drug release behavior. These technologies enhance precision and efficiency in gastroretentive drug delivery systems development, promising further improvements in drug delivery effectiveness and patient adherence.
The Effectiveness of Child Injury Database and Registry in Identifying Children Who are Potentially at Risk of Abuse: A Systematic Review
Authors: Jamaludin Anne Noor Sri Juwaneeta
Published: January 2024

Background: Child injury is a major cause of morbidity and mortality. The aim of this study is to systematically review trauma and injury databases and/or Child Protection Registries available globally that include children ≤18 years and to determine their effectiveness in identifying children potentially at risk of abuse within the community. Methods: Four high-yield electronic databases were searched, they were PubMed, EMBASE, PsychInfo and ProQuest to retrieve articles studying child injury databases. Full articles published in English from 2006 to 2016 that met the inclusion criteria were chosen. The included articles were appraised and evaluated by three reviewers independently. Results: Overall, 12 articles that studied child injury databases were selected. The articles were then categorized into five themes: 1) risk factors; 2) characteristics of abused children; 3) repeated admission; 4) concordance with other databases; and 5) presentation at the emergency department. The effectiveness of each theme in identifying children who are potentially at risk of abuse was then evaluated. Injury databases that used characteristics of abused children as a theme in identifying abuse cases were shown to be the most effective, followed by risk factors (fairly effective), repeated admission (fairly effective) and concordance with other databases (fairly effective). Presentation at the emergency department was shown to be not effective in predicting child abuse. Conclusion: Existing studies showed that there are still limitations in databases for identifying children at risk of abuse. The set-up of an integrated database with linkage to other databases will increase efficiency in detection and assist in early identification of children potentially at risk of abuse in the emergency setting.
Effect of Maternal Sensitiveness and Demographic Variables on Auditory and Speech Outcomes in Pediatric Cochlear Implant Users-Prospective Study
Authors: Sarathy Kamala
Published: January 2024

Background: Congenitally deaf children receive cochlear implantation at a young age to gain almost ordinary language development. Improvements in children’s functioning after cochlear implantation are noted particularly in their spoken language and ability to communicate. However, the rehabilitation technique following pediatric cochlear implantation rests heavily on parental involvement in some important dimensions. Methods: A prospective study was carried out to determine maternal sensitiveness using parental questionnaire administered on parents of 205 children who have undergone Cochlear implant surgery and aural rehabilitation. The parental questionnaire was administered through telephone monitoring interview and face to face interview, Results: A significant difference between parental questionnaires in terms of auditory and speech outcome measure were observed. On analysis maternal education and age of implantation has a significant effect on parental sensitiveness score and auditory and speech outcome scores. No significant correlation was observed between implant ages, number of siblings with parental sensitiveness, CAP & SIR score. Conclusion: This study shows that maternal sensitiveness or responsiveness towards cochlear implant recipient, higher maternal education, implantation within critical period and demographic variables like family structure had greater effect on auditory and speech development in cochlear implant recipient.
Prevalence of Urinary Tract Infection and its Related Factors in a Sample of School Age Children from Baghdad Iraq
Authors: J Abdulameer Atheer
Published: January 2024

Background: Urinary tract infection is considered an important risk factor for the development of renal insufficiency or endstage renal disease. Children have a wide variety of clinical presentation, ranging from the asymptomatic presence of bacteria in the urine to potentially life- threatening infection of the kidney. Objective: To measure the prevalence of urinary tract infection, bacteriuria whether symptomatic or not, the type of bacteria detected in urine, and to identify the factors that may be associated with urinary tract infection in primary in school going children. Methodology: A cross-sectional study with analytic elements was conducted within five months in pediatric department of Al Imamain Kadhimain Medical city. A consecutive sample of 300 children of school age (6-12) years old included, data were collected by direct interview with children and/or their caregiver using a questionnaire with measurement of weight and height, general urine examination and urine culture were done. Results: The prevalence of children having positive urine culture was 14.7% of which 1.6% was of children without any symptoms. E.coli being the most frequent detected organisms 65.9%, with significant predisposing behaviors including: intake of carbonated beverages, holding back urine, not washing hands after toilet and using tight clothing. Conclusion: The prevalence of urinary tract infection among school age children in is relatively low and it is significantly related to school dropout, low educational level of parents, rural residence, and low family income.
A Neonate with Amniotic Band Syndrome and Osteomyelitis
Authors: Moshfegh Fereshteh
Published: January 2024

Background: Amniotic band syndrome (ABS) comprises of a spectrum of congenital malformations involving the limbs more often, but any other anatomic region of fetus could be involved. Its prevalence has been reported to range from 0.19 to 8.1 per 10000 live births. There are different theories for explaining the etiology of amniotic bands, but it has been considered to have a multifactorial etiology. Fetoscopic release of amniotic bands affecting one or more extremities can prevent limb loss or preserve limb function when distal fellow is still identifiable on preoperative ultrasound scans. ABS occurs in 77% of fetuses with multiple anomalies. Both males and females are equally affected. Osteomyelitis in neonates is relatively uncommon, but burdened with an increased hospital stay and possible long-term sequela if not diagnosed on time. The long bones are the most frequently affected sites. Case Presentation: Here we are introducing a neonate with left upper extremity necrosis due to ABS which needed amputation and it was associated with severe chronic osteomyelitis. Conclusion: Amniotic band syndrome mostly involves the limbs. It is important to diagnose it as soon as possible, because with the interprofessional teamwork approach, an optimal patient result with fetoscopic or surgery procedures could be achieved.