bluuebunny/crossref_metadata_2025 huggingface dataset:
Pembentukan Gas Metan dari Karbon Dioksida Menggunakan Katalis Ni/Al2O3 dengan Penambahan Mn Sebagai Promotor
Authors: Friema Jihan Syahira Syifa , Junaidi Robert , Zamhari Mustain
Published: December 2023

Carbon dioxide (CO2) emissions are a type of greenhouse gas emission which is the main factor in the emergence of the global warming phenomenon. Based on the total CO2 emissions released, there are 3 components that most influence high CO2 emissions, namely the electricity sector (42%), transportation (23%) and housing (6%). The trend of increasing CO2 will continue if no preventive measures are taken globally. One of these preventive efforts is to convert carbon dioxide (CO2) into methane (CH4), or known as the methanation process of carbon dioxide. In the field of fuel, the conversion of carbon dioxide into methane gas has more advantages in terms of thermodynamics. One of the factors that determine the methanation process is the activity of the catalyst. The catalyst used in this study was the Ni/Al2O3 catalyst. Ni/Al2O3 catalyst is a catalyst that has good performance in the methane formation process. However, the Ni/Al2O3 catalyst has disadvantages, one of which is that it is susceptible to carbon deposition and sintering on the catalyst. One way to improve catalyst stability performance is by adding a promoter. This research was carried out by varying the temperature, the amount of Ni/Al2O3 catalyst and adding a promoter to give structural changes to the catalyst. The results showed that the temperature and the amount of catalyst affect the amount of CH4 formed, and the addition of manganese (Mn) initiator can affect the pore structure ofÂ theÂ catalyst.
Hubungan Perilaku dan Pengawasan Terhadap Penerapan 5S Pada Pekerja di Departemen Jetty PT. XYZ
Authors: Arifin Rafli Rizkina , Negoro Yanuar Pandu , Hidayat Hidayat
Published: December 2023

Companies must not only offer appropriate infrastructure in their production processes to attain optimum profitability, but they must also cultivate a healthy corporate culture. Univariate analysis is used to describe the properties of each variable's frequency distribution in the table. Bivariate analysis, on the other hand, is used to assess the association between two variables, with the chi-square test used to determine the link. Several adjustments are proposed to boost the efficacy of using the 5S Method. These enhancements may be made by conducting bivariate and univariate analyses to discover variables that impact the performance of the 5S Method implementation. This allows proposals for improvement to be developed and executed. To define the measuring scale, researchers utilized a Likert scale to disseminate the questionnaire. The signature value of 0.044 is less than the 0.05 significance threshold, hence the null hypothesis (H0) is accepted and the alternative hypothesis (Ha) is rejected. As a result, it is possible to infer that there is a considerable link between work supervision and 5S implementation in the PT XYZ Jetty department. According to the research results, there is a link between the conduct of XYZ workers and the monitoring of the 5S implementation process.
Designing Commercial Vertical Housing with the Implementation of Modular and Prefabricated Architecture
Authors: Jura Cosgrove Amadeus Bernafield , Ismanto Riyadi , Ulinata
Published: December 2023

Residence or housing is one of the basic needs of humans. Each individual has different housing needs based on their social, economic, and cultural aspects. This diversity requires housing design solutions with various design variations that can meet the residents' needs. Vertical housing has become one answer to fulfilling housing needs, but the quality of life in vertical housing is often considered worse compared to conventional housing. Currently, the constructed vertical housing buildings lack high spatial flexibility, as they typically have fixed forms and limited living space that restricts the flexibility for occupants. Commercial vertical housing with the application of modular architecture and prefabrication is one approach that can provide a solution to dynamic living needs quickly and responsively to the environmental typology, while also providing open spaces for residents to enhance their quality of life.
Ulster versus Éire: Border Narratives in Cinema Newsreels
Authors: Chambers Ciara
Published: December 2023

Ulster versus Éire (1938) was an American March of Time newsreel exploring the complexities of Irish politics on both sides of the border. It came hot on the heels of an earlier film made by the same company, misleadingly titled Irish Republic (1937). The first film had sparked an attempt by the Northern Ireland government to present a propagandised film about the north in response to what was seen to be a favourable depiction of the south. Remarkably, the two films utilised much of the same footage to present two starkly contrasting narratives of ‘two Irelands’. This article explores how representations of the border in cinema newsreels failed to fully reflect the complexities of partition, but very clearly established a partitionist mentality in depicting two separate peoples, north and south of the border. The growth of this partitionist mentality is traced through stories covering the Home Rule movement and partition of Ireland in the 1910s and 1920s, the growing divide between north and south during the economically turbulent 1930s and the pressure placed on Ireland to reconsider its neutral status during the Second World War. Against this backdrop, the newsreels function as both a reflective cultural barometer of shifting perspectives on Ireland throughout the early twentieth century and an active Althusserian ‘Ideological State Apparatus’ in embodying and circulating British and American political attitudes to the border in an 'unofficial' capacity.
Staging the Border: Interview with Oisín Kearney
Authors: Heinen Sandra , Kearney Oisín
Published: December 2023

Interview with writer and director Oisín Kearney
The Palearctic view on a bat fungal disease
Authors: Whiting-Fawcett Flora , Blomberg Anna , Troitsky Tanya , Field Ken , Puechmaille Sébastien , Lilley Thomas
Published: December 2023

The fungal infection causing white-nose disease in hibernating bats in North America has resulted in dramatic population declines of affected species since it was first discovered in 2007. Shortly after, it was demonstrated that the causative agent, Pseudogymnoascus destructans, is native to the Palearctic, where it also infects several bat species. However, infection in the Palearctic rarely leads to severe pathology or the death of the host, suggestive of a lengthy coevolution between the host and pathogen. An understanding of the unique relationship between the host, the pathogen and the environment in the Palearctic can provide valuable insights into how the epizootic may continue to develop in the Nearctic, and how to effectively manage the disease. The local extirpation and changes in conservation status of affected species in North America has triggered a surge of research across a plethora of fields in bat and fungal biology, in both North America and Eurasia. Here, we summarise current knowledge on the fungal infection, from how P. destructans infects bats, to the delicate interplay between the pathogen, host and the environment, and to how individuals, species and populations respond to the fungal pathogen. We conclude on how tolerance is likely manifested in Palearctic bat species and whether there is potential for the development of tolerance in the Nearctic. We conclude with a systematic review of current literature on the management of the disease in North America and how it could best benefit from knowledge garnered from Eurasia. Our essay encourages policymakers and conservation managers to take a more holistic consideration of the epizootic.
Прогнозирование и лечение пародонтита* на основе мониторинга стволовых клеток в периферической крови пациентов
Authors: Иорданишвили А.К.
Published: December 2023

Цель исследования. Изучить возможность использования стволовых клеток в клинической пародонтологии для оценки эффективности лечения и прогнозирования течения хронического генерализованного пародонтита.
Объекты и методы исследования. Проведено одноцентровое проспективное клинико-лабораторное исследование, в котором приняли участие 35 пациентов в возрасте от 51 года до 65 лет, имеющих хронический генерализованный пародонтит или редуцированный пародонт*. Пациентам с пародонтитом проводили общепринятое комплексное лечение и одновременно исследовали динамику количества стволовых клеток в периферической крови. Ее оценивали по данным проточной цитометрии, выполнявшейся на проточном цитометре с применением тройной комбинации прямых моноклональных антител CD34FITC/CD38 PE/CD45 PerCP.
Результаты исследования и их обсуждение. Установлено, что у пациентов с хроническим генерализованным пародонтитом в периферической крови существенно снижается содержание стволовых клеток «CD34+CD38-» в сравнении с пациентами, ранее страдавшими этим заболеванием, но в поле комплексного лечения у которых отсутствуют клинические проявления гингивита и пародонтита, а состояние тканей пародонта характеризуется как редуцированный пародонт. Показано, что динамика стволовых клеток в периферической крови в процессе успешного комплексного лечения хронического генерализованного пародонтита имеет свои закономерности и согласована с клинической картиной течения заболевания. Стволовые клетки при эффективной терапии в послеоперационном периоде обеспечивают компенсаторно-приспособительную реакцию организма человека, направленную на купирование воспалительного процесса и регенерацию костной ткани в очаге поражения. Такой реакции стволовых клеток при появлении осложнений во время хирургического лечения пародонтита не выявлено.
Заключение. Определение содержания и мониторинг стволовых клеток в периферической крови пациентов, страдающих хроническим генерализованным пародонтитом, является серьезным прогностическим признаком клинического течения этого заболевания.
Pengaruh Motivasi, Lingkungan, Disiplin, dan Keadilan Organisasi terhadap Kinerja Karyawan
Authors: Ayu Nur Luthfi , Kharismasyah Alfato Yusnar , Astuti Herni Justiana , Widhiandono Hengky
Published: December 2023

Penelitian ini bertujuan untuk menganalisis pengaruh motivasi kerja, lingkungan kerja, disiplin kerja, dan keadilan organisasi terhadap kinerja karyawan di Laksana Baru Swalayan Majenang. Metode penelitian yang digunakan adalah survei dengan menggunakan kuesioner sebagai instrumen pengumpulan data. Data yang diperoleh dianalisis menggunakan PLS. Hasil penelitian menunjukkan bahwa motivasi kerja, lingkungan kerja, disiplin kerja, dan keadilan organisasi berpengaruh positif signifikan terhadap kinerja karyawan. Motivasi kerja dan lingkungan kerja memiliki pengaruh positif yang kuat terhadap kinerja karyawan, sedangkan disiplin kerja dan keadilan organisasi memiliki pengaruh positif yang moderat terhadap kinerja karyawan. Maka, Laksana Baru Swalayan Majenang perlu fokus pada peningkatan motivasi dan lingkungan kerja karyawan, serta meningkatkan disiplin kerja dan keadilan organisasi untuk meningkatkan kinerja karyawan. Penelitian ini diharapkan memberikan kontribusi bagi pengembangan manajemen sumber daya manusia di Indonesia.
Kolaborasi Mining Management Dengan Good Mining Practice Dalam Peningkatan Kinerja Perusahaan
Authors: Sastradi Handy , Dwi Putranta A.A. Bagus Dinariyana
Published: December 2023

Penelitian ini bertujuan untuk mengidentifikasi kemampuan level Management Site terhadap penguasaan Mining Management, mengidentifikasi hal apa saja yang berkontribusi terhadap ketercapaian target produksi, menentukan besaran nilai yang mempengaruhi penilaian GMP. Elemen penilaian GMP diantaranya kompetensi Penanggung Jawab Operasional/Project Manager, kesiapan dokumen kontrak kerja, system pelaporan proyek, penggunaan tenaga lokal, penggunaan subkontraktor lokal, kompetensi tenaga kerja, pengutamaan produk dalam negeri dan inovasi. Pada penilaian tersebut PPA akan melakukan peningkatan dalam kesiapan kompetensi Penanggung Jawab Operasional/Project Manager, sistem pelaporan dari aktivitas pertambangan, penggunaan dan pengelolaan alat berat operasional. Metodologi dilakukan dengan 4 (empat) tahapan yaitu identifikasi kemampuan level Management Site terhadap penguasaan Mining Management melalui metode kuesioner diambil dari level Project Manager, Section Head, Group Leader. Pengumpulan data alat berat Heavy Dump Truck berupa payload, load time, speed, empty stop time, fuel dilanjutkan pengolahan Regresi, Multivariate dan Cluster untuk mengidentifikasi data yang paling berpengaruh terhadap kontribusi produksi. Identifikasi aktivitas dan pemberian bobot penilaian berupa katagori interval persentase pada area Front Loading, Road Maintenance dan Disposal. Penelitian ini menghasilkan penguasaan Mining Management yang baik, perbaikan pada elemen HDT, penyusunan aktivitas dan penilaian area kerja, perumusan strategi perusahaan dalam peningkatan penilaian GMP.
Rancang Bangun Laman Penyetaraan Ijazah Menggunakan Metode Reuse-Based Software Development
Authors: Kresnala Dany Prima , Padri Abdul Robi , Henderi
Published: December 2023

Teknologi informasi telah memberikan banyak manfaat bagi masyarakat dalam mengakses layanan publik, termasuk penyetaraan ijazah dan konversi nilai indeks prestasi kumulatif (IPK) bagi lulusan perguruan tinggi luar negeri. Namun demikian, terdapat tantangan operasional dalam menghasilkan laporan yang dibutuhkan, karena masalah database. Hal ini menyebabkan keterlambatan dalam perbaikan dan pemenuhan Service Level Agreement (SLA). Untuk mengatasi hal ini, diusulkan sebuah Sistem Informasi baru dengan menggunakan metode Reuse Based Software Development. Tujuannya adalah untuk menunjukkan bahwa pendekatan ini dapat mempercepat pengembangan platform penyetaraan ijazah dan konversi nilai IPK dengan memastikan layanan yang sudah ada tidak terganggu  dan dapat memenuhi SLA dengan meningkatkan efisiensi serta efektifitas proses bisnis yang ada. Platform baru ini tidak hanya akan menyederhanakan proses tetapi juga memperkenalkan elemen-elemen inovatif seperti Application Programming Interface (API), yang dapat digunakan oleh para pembuat kebijakan lainnya, bahasa pemrograman yang terstandar sehingga mudah ketika ada pergantian tim pengembang.
Peran Teknologi Informasi Dalam Mendukung Komunikasi Politik Melalui Media Digital Dalam Industri Musik Dangdut
Authors: Hariyanto Bambang , Anom Erman , Iswadi
Published: December 2023

Tujuan penelitian ini adalah untuk mengetahui sisi lain dari media komunikasi yang digunakan dalam konteks politik, khususnya dalam aspek media teknologi digital. Secara khusus, penelitian ini mengkaji dari fungsi musik dangdut dan media teknologi digital sebagai alat komunikasi dalam ruang politik yang lazim dilakukan di Indonesia. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif, dengan jenis penelitian yakni studi kasus. Berdasarkan penelitian yang dilakukan, diketahui jika penggunaan musik dangdut dalam komunikasi politik telah membawa dampak positif terhadap elektabilitas partai. Musik dangdut dengan daya tariknya yang luas, juga kemampuannya untuk membangun ikatan emosional, dan potensinya untuk menciptakan atmosfer positif dan viral di berbagai platform digital dalam kampanye politik telah membantu partai politik atau kandidat untuk memenangkan hati pemilih. Namun, penggunaan musik dangdut hanya merupakan salah satu elemen dari strategi komunikasi politik yang efektif. Pesan politik yang kuat, kepemimpinan yang meyakinkan, dan rencana kampanye yang terorganisir dengan baik juga merupakan faktor penting dalam mencapai elektabilitas yang tinggi
Human Stem Cell Transplantation: An Overview Of The Islamic Perspective's Ethical Issues In Malaysia
Authors: Hehsan Muhamad Rafiqi , Mohd Pazudin Imran , Rosdin Muhammad Afif , Wan Izudin Wan Athirah , Yustisia An Nisa , Nahdah Nisya Oktia , Dahalan Zulkifli
Published: December 2023

Stem cells have unprecedented promise for treating disorders that are not amenable to conventional treatment because of their special capacity to maintain, replenish, and repair all tissue types. Stem cell research is currently surrounded by several pressing ethical and challenges as a result of the quick development of biotechnology. Therefore, the purpose of this study is to find out the ethical issues regarding the use of stem cells and correlate from an Islamic perspective, focusing on Malaysia. In this review, we outline an overview of the most significant ethical issues with stem cell application that the community especially Muslims should be aware of. The study applied a library-based methodology and gathered data about stem cells, their use, ethical concerns, and Islamic law with an emphasis on Malaysia from a range of sources, including books, websites and journals. The findings demonstrated that there are three main areas of ethical concern for stem cell technology from an Islamic perspective: human embryonic stem cells, stem cells used for aesthetic purposes, and stem cells used for therapeutic medicine. We attempted to correlate Malaysia's perspective with some of the Islamic perspective's points on all ethical concerns. We discovered that there are certain arguments towards every ethical issue from an Islamic perspective, and we tried to compare it to the perspective from Malaysia. Both the use of current ethical frameworks and careful evaluation from an Islamic perspective are important as this vast and diverse area of stem cell technology progresses, especially in Malaysia.
我国体能训练的研究热点与实践启示
Authors: 李 清源 , 侯 太甫 , 齐 梦鑫
Published: December 2023

体能训练领域研究热点包括多样的训练方法、融合非训练策略和科技化训练。然而，困境也存在：理论滞后于实践，训练水平参差不齐。展望未来，需要加强体能理论创新，拓展国际视野，并关注体能训练的关键问题，推广与应用。解决这些问题可以提升训练质量和水平。
An Osteopathic Approach to Urinary Incontinence Including Biopsychosocial Aspects and Multiple Modalities for a Holistic Approach to Optimize Ongoing Care
Authors: Trivelas Nicholas , Slaughter Kirby , Zaremski Kenneth , Kirila Carol
Published: December 2023

Urinary incontinence is a nuanced and stigmatized condition that causes significant challenges for a large number of people in the United States and imposes a large financial and community burden. We provide an overview of major categorizations of incontinence by type as well as potential etiologies. We discuss how this condition impairs self-image, interferes with socialization, and can lead to depression and isolation; these elements inter-relate with access to care and implementation of the therapeutic options, further exacerbating patient suffering. We recognize the key components of patient evaluation regarding history and physical examination. Medicinal, surgical, and assistive device use are reviewed. Osteopathic manipulative treatments addressing the structures of the pelvis are also reviewed in detail. We illustrate how these techniques can be used to optimize outcomes. Utilizing a holistic approach to mitigate the multiple challenges that this condition presents can lead to greater success, reduced distress, and improved patient satisfaction.
Diagnosis and Management of Ectopic Pregnancy
Authors: Kukla Allie , Hogge Katelyn , Tjiattas-Saleski Lindsay
Published: December 2023

Ectopic pregnancy (EP) is a serious obstetric complication that can be life-threatening. Age-adjusted incidence of ectopic pregnancy is roughly 15.8 pregnancies per 1000. Despite this seemingly low value, EP remains one of the largest contributors to maternal mortality in the first trimester. While some patients require urgent surgery, there is a role for medical and conservative management in patients who are hemodynamically stable. In cases where medical or conservative management is appropriate, family physicians can choose to manage this condition with collaboration from the patient’s obstetrician. Particularly for residents in the 50% of US counties with no obstetrician, it is imperative for family doctors to diagnose EP quickly and accurately
Osteopathic Manipulative Treatment for Chronic Bronchiectasis
Authors: Abend David , Powell Leonard , Sivanandam Abiram , Nayar Rahul
Published: December 2023

Bronchiectasis is an uncommon chronic obstructive lung disease caused by chronic airway inflammation leading to irreversible bronchial dilation and destruction of medium-sized airways. In this case, we treated a bronchiectasis patient with a combination of osteopathic manipulative treatment (OMT) techniques including myofascial release and lymphatic techniques as adjunctive treatments in addition to other pharmacologic and nonpharmacologic therapies; OMT was shown to improve subjective symptoms of airway congestion as well as reduce frequency of emergency room visits and hospital admissions for this patient.
Prevotella Denticola Dacryocystitis and Abscess in a Child with Goldenhar Syndrome
Authors: Yang Karen , Oleske Jessica , Rishmawi Sami , Sahhar Hanna
Published: December 2023

Dacryocystitis is the inflammation of the nasolacrimal sac and is due to obstruction of the nasolacrimal system or lacrimal stagnation, leading to favorable environments for infection. Any disruptions to the nasolacrimal pathway can increase the risk of dacryocystitis. Here is a unique case of Prevotella denticola dacryocystitis that progressed into cellulitis and abscess formation in a 7-year-old female with a medical history of Goldenhar syndrome, recurrent dacryocystitis, and periodontal disease. The patient presented with standard dacryocystitis symptoms—tenderness to palpation, erythema, and edema to the medial canthus. The patient was treated empirically with vancomycin, ceftriaxone, and clindamycin. She was discharged home on clindamycin with symptomatic improvement and plans for dacryocystorhinostomy. Goldenhar syndrome is a rare congenital craniofacial malformation disorder due to aberrant morphogenesis in structures derived from the first and second branchial arches. P. denticola is an anaerobic gram-negative bacillus significant to the oral microbiome. There is currently limited research suggesting the relationship between Goldenhar syndrome and dacryocystitis complicated by Prevotella denticola. Based on the patient’s medical history, we predict that her complex presentation was secondary to the dissemination of Prevotella from her oral cavity. This case report emphasizes the importance of gram-negative anaerobic coverage in complicated dacryocystitis in patients with nasolacrimal defects.
Comparison of Photon and Neutron Radiation Dosimetric Systems Used in Organizations of Rosatom State Corporation for Control in A Planned Exposure Situation
Authors:   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia, Kochetkov O.A. , Tarasova E.Yu. ,   The Federal Unitary State Enterprise – “Russian federal nuclear center – VNIIEF”, Sarov, Russia, Shinkarev S.M. ,   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia, Rumyantsev E.A. ,   The Federal Unitary State Enterprise – “Russian federal nuclear center – VNIIEF”, Sarov, Russia
Published: December 2023

Purpose: Using the example of reviewing and discussing the results of comparison tests of dosimetric systems of gamma and neutron radiation used in organizations of the State Corporation “Rosatom”, to assess the current state of reliability of monitoring the planned exposure of workers in fields of mixed gamma-neutron radiation using the considered dosimetric systems in order to produce recommendations for corrective actions to ensure a unified approach to conduct individual dosimetric control of external exposure. Results: All measuring instruments for individual dose equivalent of photon and neutron radiation, presented in comparison tests, comply with up-to-date requirements for individual dosimetric control systems. All measuring instruments confirmed their measuring capabilities, showed satisfactory quality of measurement results and the absence of a systematic bias in the measurement results. Analysis of the results of measuring the individual dose equivalent of neutron radiation showed that problems affecting the quality of the results obtained were identified in the considered instruments of measuring personal dose equivalent. The following factors might be the sources of problems: lack of knowledge about the real characteristics of radiation fields (spectral characteristics, radiation direction, etc.) at workplaces; insufficient research of the method used for measuring neutron radiation under real conditions (technical and metrological characteristics and features of the individual dosimeters used); failure to take into account the weighing coefficients for neutrons of various energies when measuring instruments are calibrated and when real measurements are conducted. Conclusion: It is necessary to organize and conduct investigations of the metrological characteristics of the measuring instrument that are used under conditions typical for a specific radiation object. After finishing these experimental studies, it is recommended to test the methodology with an analysis of the compliance of the accuracy indicators with the requirements of the relevant guidelines. In order to solve the problem of a lack of knowledge about the real characteristics of radiation fields, radiation safety services of organizations are recommended to organize and conduct research aimed at studying such characteristics using radiometric and spectrometric methods, experimental modeling of the process of personnel exposure using anthropomorphic phantoms and determining correction factors for the individual dosimeters used.
Effect of Radiation and Non-Radiation Factors on the ТBX21 Concentration in lysates of the Mitogen-Stimulated Mononuclear Cells
Authors:   Urals Research Center for Radiation Medicine, Chelyabinsk, Russia, Kodintseva E.A. ,   Chelyabinsk State University, Chelyabinsk, Russia, Akleyev A.А. ,   South-Ural State Medical University, Chelyabinsk, Russia
Published: December 2023

Purpose: To evaluate the effect of radiation and non-radiation factors on the intracellular concentration of the ТBX21 transcription factor in peripheral blood PHA-stimulated mononuclear cells of chronically exposed residents of the Techa Riverside settlements in the long-term period after the start of exposure. Material and methods: The main group consisted of 30 people aged 67–80 years with the mean dose to the red bone marrow 867±136 mGy, to thymus and peripheral lymphoid organs 125±20 mGy. The comparison group included 10 unexposed people aged 63–82 years. The main and the comparison groups had similar sex and ethnic composition. Peripheral blood mononuclear cells were PHA-stimulated for 24 hours. Cellular lysates were normalized by total protein concentration prior to being used for ELISA test. Results: After 24 hours of incubation the median and interquartile range of the intracellular TBX21 concentration in mononuclear cells was 34.2 (6.6–86.0) pg/ml after the mitogen stimulation, and 0 (0–24.9) pg/ml – without mitogen stimulation (р=0.001). In the comparison group these values made up 24.8 (0.2–47.6) and 13.0 (0–19.2) pg/ml, respectively Conclusion: The intracellular TBX21 concentration after 24-hour mitogen stimulation did not differ statistically significantly in chronically exposed and unexposed people, as well as in people from different dose groups. Statistically significant increase in TBX21 concentration in the lysates of mononuclear cells that were PHA-stimulated for 24 hours relative to non-mitogen stimulated cells was noted in chronically exposed people with medium and high doses to the red bone marrow. No correlation was revealed between the TBX21 concentration and dose characteristics, sex, and ethnicity of the studied individuals. The results are preliminary.
Brachytherapy of Malignant Neoplasms of the Cervix Uteri: Current Status of the Problem (Literature Review)
Authors:   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia, Zavyalov A.A. , Solodova A.N. ,   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia, Tyryshkin A.I. ,   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia, Kryakvina E.V. ,   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
Published: December 2023

Purpose: To conduct a search and generalization of literature data to assess the relevance and prospects for the development of brachytherapy in the treatment of cervical cancer. Material and methods: Scientific sources were searched in PubMed / Medline for the following key words: «cervical cancer», «radiotherapy», «brachytherapy». The time horizon covered 2016–2023. Using a time filter, the most relevant and innovative research papers on cervical cancer brachytherapy were selected. Results: Modern radiology provides specialists with a wide range of methods, one of which is brachytherapy (BT). Brachytherapy is a promising direction in the treatment of cervical cancer, however, its use is largely limited and continues to gradually progressively decline around the world. The reasons associated with this are different: the complex technical component of this technique, the high requirements for the training of BT specialists, the high cost of treatment, and others. However, it should be noted that most of the current data demonstrate the high efficacy of BT in the complex therapy of cervical cancer. Therefore, research is ongoing to increase the involvement of BT in the treatment strategy for cervical cancer. Thus, many authors emphasize that the rates of primary complete remission and 5-year cancer-specific survival were significantly higher in patients treated with BT than in those who were treated with EBRT instead of BT (92.5 % versus 73.3 % and 68. 5 % versus 35.4 % respectively). Modern technical developments in the field of BT are also interesting, for example, the use of 3D printing methods. New applicators make it possible to increase the conformity of the conducted BT. The presented methodology also provides an opportunity for better training of specialists in the field of BT. An important aspect of the spread of BT and radiological treatment in general, and along with it the dynamics of the main indicators of survival, is still the socioeconomic factor. Thus, there are direct correlations between the total income of a country and the degree of prevalence of BT in it. Some countries are almost completely deprived of the possibility of using BT methods in health care. In general, brachytherapy is actively developing, opening up new horizons in the treatment of malignant neoplasms of cervical cancer.
ASSÉDIO MORAL E SEUS IMPACTOS NA SAÚDE MENTAL DO TRABALHADOR
Authors: Lucas dos Santos Geneia , Feijó Carla Aparecida , Baade Joel Haroldo , Misturini Daniela
Published: December 2023

O objetivo deste artigo foi identificar a percepção de frequência do assédio moral e seu impacto afetivo no trabalho, visando contribuir na prevenção nas organizações. A metodologia utilizada foi quanti, do tipo descritiva, de levantamento (survey), com uso de duas escalas validadas no Brasil: a EP-AMT e EIA-AMT. A determinação do universo constituiu-se de homens e mulheres que estiveram ativos no mercado de trabalho nos últimos quatro anos. A análise de dados foi através do software SPSS 22 e planilhas do Microsoft Excel. Resultados com relação a EP-AMT: 66,91% (nível profissional) e 81,36% (nível pessoal) disseram que nunca ou quase nunca perceberam assédio moral. Dentre os considerados que sofreram assédio moral, apenas 3,79% no nível profissional e 4,69% na esfera pessoal. Na EIA-AMT em 65,68% não houve impactos afetivos, 16,33% tiveram pouco impacto e 17,99% apresentaram fortes impactos afetivos com relação ao assédio sofrido. O assédio moral ainda tem sido pouco falado e combatido e ações preventivas precisam ser instituídas, bem como dispositivos que auxiliem o assediado a denunciar, situação que não pode ser resolvida apenas na esfera individual, mas na coletiva é possível.
The Role of Financial Services in the Transition to a Sustainable Economy
Authors: Svoboda Andreas
Published: December 2023

The financial services industry plays a critical role in the transition to a sustainable economy. Financial institutions can allocate resources to more environmentally friendly endeavors, manage long-term sustainability risks, and provide financing for sustainable projects.

One way that financial institutions can support the transition to a sustainable economy is by allocating capital to more environmentally friendly investments. This could include investing in renewable energy, sustainable agriculture, and green buildings. Financial institutions can also help to manage long-term sustainability risks by developing and implementing climate risk management frameworks. This will help to protect investors and financial markets from the potential financial impacts of climate change.

Finally, financial institutions can provide financing for sustainable projects through a variety of mechanisms, such as green bonds and sustainable loans. This financing can help to accelerate the deployment of clean technologies and other sustainable solutions.
IN VITRO AND IN SILICO STUDIES ON LIGNAN SECOISOLARICIRESINOL DIGLUCOSIDE
Authors: BAYAR İrem , ÇAĞLAR YAVUZ Sevtap , AKKOÇ Senem
Published: December 2023

Objective: Lignans are important biologically active compounds in diphenolic structure. Secoisolariciresinol diglucoside (SDG) is a significant type of lignan known to have anti-cancer properties. This study aimed to investigate the antiproliferative activity properties of SDG on hepatocellular carcinoma cells (HepG2), colorectal cancer cells (DLD-1), lung carcinoma (A549), and prostate cancer (PC3) cell lines.
Material and Method: Cell viability of cancer cells was determined by the MTT method after treatment with various concentrations of SDG at 48 or 72 hours. The DFT (Density Functional Theory) analysis of the SDG was performed using Spartan'10 and visualized. Drug-likeness and absorption, distribution, metabolism, excretion, and toxicity (ADME-Tox) properties of this compound were examined. Molecular docking was carried out to research the biological activity of SDG.
Result and Discussion: Our results showed that SDG exhibited significant cytotoxicity only against DLD-1 cells with IC50 value of 37.45 µM, but inactive against other cancer cell lines as in vitro. 4UYA, which biomarker for colon cancer, is the crystal structure of the MLK4 kinase domain. The binding energy value for the SDG-MLK4 kinase domain was calculated as -6.1 kcal/mol. Anticancer potential was verified by in vitro assay and in silico molecular docking study. In conclusion, this study revealed the protective aspect of SDG against colon cancer and showed that it has promising anticancer activity.
Length at life stages of the white shark Carcharodon carcharias in the western North Atlantic
Authors: Márquez-Farías JF , Tyminski JP , Fischer GC , Hueter RE
Published: December 2023

Length at life stages of the white shark Carcharodon carcharias is not well known for most of the 9 populations of this species, including in the western North Atlantic (WNA). We analyzed length and maturity data by sex for 87 white sharks with sizes ranging 138-501 cm total length (TL), captured, studied, and released by OCEARCH during 2012-2022, off the US and Canadian Atlantic coasts. A binary logistic regression was used to estimate the length-at-maturity (L50) for the WNA white shark with a Bayesian statistical framework using a Markov chain Monte Carlo method for numerical integration. Different trials using noninformative and informative priors were tested. The posterior probability distribution for L50, steepness of the model (φ), and 95% credible intervals (CI) of the logistic model for females were L50 = 411.3 cm TL (CI: 390.8-432.6 cm TL) and φ = 10.5 (CI: 5.7-17.8) and for males were L50 = 334.9 cm TL (CI: 321.2-348.2 cm TL) and φ = 7.5 (CI: 4.2-12.4). These L50 values are somewhat smaller than previously reported sizes-at-maturity for both sexes of this species. An ordinal logistic regression allowed us to determine the probability of being in the various life stages (young-of-the-year, juvenile, and adult) at a particular size. Estimating the length at any life-history stage of white sharks along with age estimates is useful for determining the reproductive value of the population and ultimately for estimating the relative contribution (elasticity) of vital rates to population growth.
ANÁLISE TÉCNICA DE INTERVENÇÃO CORRETIVA EM BOMBA CENTRÍFUGA
Authors: SANTOS Alison Fabricio Costa dos , BOVÉRIO Maria Aparecida , SILVA Dejaime Pereira da
Published: December 2023

As bombas centrífugas são utilizadas amplamente na indústria para transporte de fluidos, são projetadas para trabalhar a uma determinada vazão com uma estipulada altura manométrica de recalque. No entanto, elas podem ter falhas. Nesse sentido, o objetivo desse trabalho foi o de estudar como se realiza uma análise técnica de intervenção corretiva em bomba centrífuga, por meio de uma revisão bibliográfica, um estudo de caso e uma pesquisa aplicada. Os resultados indicaram a necessidade de se utilizar os materiais corretos para recuperação do equipamento, além da limpeza, para proteção de problemas associados à abrasão, erosão, corrosão, ataque químico e corrosão atmosférica. Concluiu-se que a manutenção corretiva do equipamento foi diretamente relacionada à necessidade de proteção com polímeros de baixo coeficiente de atrito, pois melhorou o seu desempenho.
ESTRATÉGIAS DE VENDAS ORIENTADAS AOS CANAIS DIGITAIS NOS PEQUENOS E MÉDIOS VAREJISTAS DO SEGMENTO ALIMENTAR
Authors: Pimentel Fabio Henrique de Oliveira , Lima Gustavo Barbieri
Published: December 2023

O objetivo central da presente pesquisa é identificar quais canais de vendas digitais possuem maior potencial de crescimento em vendas e incremento de receita financeira nos pequenos e médios varejos do segmento Alimentar, assim como apontar os principais gaps existentes nos processos de definição e implementação de estratégias de vendas em canais digitais para transformá-los em oportunidades. Para tal, realizou-se uma pesquisa qualitativa, na qual foram entrevistadas 07 pessoas, seguindo-se um roteiro de entrevista pré-definido. Os principais resultados apontaram que: a maioria enxerga relevância e já atua com canais digitais de vendas, onde a ferramenta mais utilizada é o Whatsapp; o nível de relevância atual dos canais de vendas digitais em sua maioria oscila entre baixo e médio, contudo, há um grande interesse em aumentar a relevância desses canais em seus negócios; para isso, a empatia para com os clientes é o principal direcionador na elaboração da estratégia de atuação nos canais digitais de vendas e as principais fontes utilizadas são as próprias experiências de mercado e os fornecedores; as grandes dificuldades no desenvolvimento dos canais digitais de vendas é necessidade de investimento e a falta da mão-de-obra qualificada no quadro atual de colaboradores.
A Study on Comparison of ‘Naturalness’ with ChatGPT, NMT and Publisher’s English Textbook
Authors:   The Korean Society of Culture and Convergence, Hur Gun , Kim Dongmie
Published: December 2023

The purpose of this study is to compare and discuss how well the publisher, ChatGPT, and NMT have preserved 'naturalness' in translating TOEIC textbooks. In order to engage in such a discussion, we compared and analyzed all the translations in the beginner-level TOEIC textbook's explanation booklet provided by Company H. These were classified into four categories for analysis: firstly, 'violation of naturalness' due to excessive use of foreign language, secondly, 'violation of naturalness' due to indiscriminate use of passive/active voice, thirdly, 'violation of naturalness' due to abbreviated translation, and fourthly, 'violation of naturalness' due to literal translation of vocabulary. The analysis results revealed that none of the three types of translations perfectly preserved 'naturalness.' In particular, Company H's textbook translations required a slightly more learner-oriented naturalness than ChatGPT or machine translations.
A Study on the Change of Chinese Students' Perception of Korean Image: Focusing on In-depth Interviews with Culture and Arts Majors at Hongik University
Authors:   The Korean Society of Culture and Convergence, Lu JunYu , Joo Hee Hyun
Published: December 2023

This paper aims to explore the changes in the perception of Korea before and after the arrival of Chinese students who chose culture and art-related majors based on their affinity with Korean culture. Based on previous studies, the country image was divided into four areas: economy, politics and relations, nation, and culture. A deep interview survey was conducted and analyzed to examine the changes in the country image. The economy image changed from city image to consumption image, the politics and relations image changed from Korean understanding to Korean understanding, and the country image changed from social atmosphere perception such as organizational culture to cultural arts participation. These changes in country perception had an impact on the adaptation of Korean life, stress coping, stay and employment of Chinese students.
A Study of Instructor Perceptions on the Evaluation of Korean Language Learners in University General Education Classes
Authors:   The Korean Society of Culture and Convergence, Kim HyoEun
Published: December 2023

The purpose of this paper is to investigate and analyze instructors’ perceptions of learner evaluation in university Korean language class as a general education course and derive implications. To this end, an interview survey was conducted with five instructors. According to the results of analyzing the instructors’ perceptions, first, it was revealed that in terms of setting the examination by the instructors on their own, they say that making the listening test is a great burden on them. In addition, the instructors were not sure about the difficulty and validity of the tests they presented. And the feedback is not properly given after the completion of the comprehensive evaluation at the end of the semester. Furthermore, it was found that the evaluation needs to reflect the characteristics of Korean for academic purposes. In conclusion, for the evaluation, it is necessary for the instructors to interact actively, and it is needed to discuss the results of the survey on their perceptions in detail afterwards.
The Influence of Teachers' Digital Literacy Competencies on Pedagogical Modification and Practical Knowledge
Authors:   The Korean Society of Culture and Convergence, Park Seonhyang , Yoon Haerim
Published: December 2023

The primary objective of this study was to explore the influence of digital literacy competencies on two pivotal factors related to teachers' instructional expertise: pedagogical modification and practical knowledge. To facilitate this, a survey was undertaken among school teachers in Area A, with a total of 150 participants. From this, after filtering out insincere responses, 117 valid responses were analyzed. For the survey analysis, SPSS 20.0 was employed, conducting frequency analysis, descriptive statistics, correlation analysis, and regression analysis. The findings illustrated that teachers greatly value digital literacy competencies, pedagogical modification, and practical knowledge. A notable correlation between these areas was also identified. Importantly, digital literacy competencies showed a significant influence on both pedagogical modification and practical knowledge. This research emphasizes the importance of digital literacy in teacher education and provides foundational data for tangible strategies in leveraging digital literacy competencies in actual educational environments.
A Case Study of Learning Facilitator Operations in Learner-Centered Instruction Using Innovative Teaching Methods: Focusing on the Case of Learning Facilitator Support Program at University A
Authors:   The Korean Society of Culture and Convergence, Seo Yonghee
Published: December 2023

This study aims to propose strategies for effective implementation and dissemination of learner-centered innovative teaching methods, as well as efficiency and quality management in large-scale instruction. To achieve this, we analyzed the case of A University's Learning Facilitator Support Program, and the findings are as follows: The Learning Facilitator Support Program has proven to be effective in facilitating the operation of classes with a large number of students. And, it has demonstrated a positive impact on academic performance. Therefore, it is concluded that strategies are needed to enhance the program's effectiveness in managing and improving the quality of instruction. These strategies should include institutional improvements at the school level, enhancements to the learning environment, improvements in operational methods and sharing strategies at the CTL level.
The Significance of “Silent Spring” as Science Nonfiction Literature
Authors:   The Korean Society of Culture and Convergence, Ahn Donghyun
Published: December 2023

“Silent Spring” is an exemplary work of ‘science nonfiction literature’ that successfully combines science and literature. Rachel Carson uses scientific evidence to persuade her readers and a variety of literary techniques to engage them. Carson masterfully intertwines scientific truths with her literary and poetic sensibilities, underscored by a profound ecological consciousness. By analyzing the criticisms of “Silent Spring” that appear in “Silent Spring at 50,” this paper seeks to more objectively evaluate Carson's arguments and explore the way forward for the genre of science nonfiction literature. The analysis reveals that some criticisms of Carson may be ascribed to the limitations of her era, while some other critiques appear unjust, given that Carson's focus diverged from that of her critics. Still other criticisms are unfairly directed at Carson. The paper suggests that Carson's work could have better exemplified scientific discourse by embracing the possibility of error and avoiding overly simplistic binary logic. By employing Carson as a reflective model, future generations can improve their ability to merge science and literature.
The Relationship between Perfectionism and Social Anxiety: The Mediating Effect of Need for Approval
Authors:   The Korean Society of Culture and Convergence, Heo Yoonjung , Heo Jaehong , Oh Chunggwng
Published: December 2023

The purpose of this study was to examine the mediating effects of need for approval(NA) on the relation between perfectionism and social anxiety(SA). To this end, Multidimensional Perfectionism Scale(HMPS), the Revised Martin-Larsen Approval Motivation Scale(RMLAM), Social Interaction Anxiety Scale(SIAS) and Social Phobia Scale(SPS) were used with 469 college students. The collected data were analyzed using SPSS 26.0 and AMOS 26.0. The results of this study were as follows. First, there was a significant correlation between self-oriented perfectionism(SOP), socially-prescribed perfectionism(SPP), NA, and SA. Second, SOP directly reduced SA and SPP directly increased SA. Third, SOP reduced SA by mediating NA and SPP increased SA by mediating NA. Based on the results of this study, counseling intervention methods for college students experiencing SA were discussed in terms of SOP, SPP, NA, and SA. Finally, the significance, limitations, and suggestions for further research were made.