bluuebunny/crossref_metadata_2025 huggingface dataset:
[Retracted] Application of Color Ultrasound in the Diagnosis of Gynecological Endocrine Disorders and Study of Ultrasonic Image Characteristics
Authors: Zhang Qun , Qi Junrong , Xiao Shanshan
Published: June 2022

In order to study gynecological endocrine disorders, color ultrasound and image examination were used for in‐depth study. After examining the clinical significance, research methods, strengthening treatment measures, and adjusting physical and mental health, the research and examination of endocrine disorders under ultrasound and ultrasound images are successfully analyzed. Endocrine is like a woman’s umbrella. When it is in harmony with the body, it will make women as beautiful as flowers. Once it becomes an endocrine disorder, it will cause a lot of trouble to women. According to the statistics of a magazine, the incidence of facial chloasma in young and middle‐aged women is 28.2%; breast cancer in women over 30 years old has a breast mass of 38.8–49.3%, of which 1–2% may be converted to breast cancer. For the treatment of patients with gynecological endocrine disorders, we mainly use simple western medicine, but the curative effect is not ideal. The rehabilitation speed of patients is relatively slow, which has certain treatment limitations. After the ultrasound research on endocrine disorders, the ultrasound can not only determine the female endocrine function but also diagnose diseases related to endocrine disorders, which basically meets the general understanding of clinicians on the screening of endocrine disorders and physiological functions.
A Comparative Study on Detection of Malware and Benign on the Internet Using Machine Learning Classifiers
Authors: Pavithra J. , Selvakumara Samy S.
Published: June 2022

The exponential growth in network usage has opened the way for people who use the Internet to be exploited. A phishing attack is the most effective way to obtain sensitive information about a target individual without their knowledge over the Internet. Phishing detection has an increased false-positive rate and is inaccurate. The motivation behind the research is to analyze and classify the applications among malware or benign with less time complexity. The main purpose is to find the algorithm which provides better accuracy for detecting the adware. The comparative analysis was made with three machine learning classifiers to find a better one. Random forest, SVM, and naïve Bayes were selected because of the better results obtained in previous research papers. Using a confusion matrix, the classifier methods were evaluated for accuracy, precision, recall, and F-measure with positive rates of both true and false. This research indicates that there are a number of classifiers that, if accurately detected, offer better reliable phishing detection outcomes. Random forest has proven to be an effective classifier with 0.9947 accuracy and a 0.017 false-positive rate. In this study, the comparative analysis reveals that the best ML classifiers have a lesser prediction accuracy for spoofing threat identification, implying that nonphishing programmers can use the best ML classifiers to evaluate the attributes of spoofing threat recognition and classification.
lncRNA HOTAIR Inhibition by Regulating HMGB1/ROS/NF-κB Signal Pathway Promotes the Recovery of Spinal Cord Function
Authors: Wang Zhe , Long Ruchao , Yang Zhihua , Feng Chunzhi
Published: June 2022

Spinal cord ischemia-reperfusion injury (SCII) is one of the most serious complications of clinical aortic aneurysm and vascular malformation surgery. Long noncoding RNA (lncRNA) is involved in the progression of SCII, whereas long noncoding RNA HOX transcript antisense RNA (lncRNA HOTAIR) is unclear in SCII. This study is aimed at confirming the role and related mechanism of HOTAIR in SCII. Later on, a model of SCII was established by clamping the aortic arch for 14 minutes. RNA expression of HOTAIR was detected via qRT-PCR at 12 h, 24 h, 36 h, and 48 h after SCII. The Tarlov scoring system and TUNEL assay were used to evaluate neurological function and neuronal apoptosis. Oxidative stress factor levels were assessed according to the instructions of the kit. Inflammatory cytokines were assessed by ELISA. Western blot was used to detect levels of p65, p-p65, I-κBα, and p-I-κBα. We found HOTAIR was raised in SCII rats. si-HOTAIR was able to reverse SCII-induced oxidative stress in SCII rats. The HMGB1 expression was upregulated in SCII tissues and negatively correlated with HOTAIR. HMGB1 was able to partially reverse si-HOTAIR inhibition of oxidative stress, inflammatory injury, and neuronal cell apoptosis in SCII. In addition, the ROS/NF-κB signaling pathway is involved in HOTAIR/HMGB1 regulation of SCII. In a word, HOTAIR inhibition is able to inhibit oxidative stress, inflammatory injury, and neuronal apoptosis in SCII through downregulation of the high mobility group protein B1(HMGB1), which is achieved by inhibiting the ROS/NF-κB signaling pathway. The HOTAIR/HMGB1/ROS/NF-κB molecular pathway may be a new mechanism for the treatment of SCII.
Effects of Body Posture and Different Exercise Intensity on Athletes’ Limb Injury
Authors: Jin Di , Ma Qian
Published: June 2022

The purpose of this study was to solve the problem of the influence of body posture and different exercise intensity on athletes’ limb injuries, to meet the needs of understanding athletes’ injuries, and to make up for the lack of investigations on athletes’ limb injuries; this also increases the chances of an athlete avoiding injury. Severe acute sports injuries of high-level gymnasts endanger the personal safety of athletes. Many movements in gymnastics are done in the air much higher than the ground, and there is no fulcrum when the athlete does the movements; this just can only maintain balance and change your body posture through your own feelings, a slight error can easily cause your head or upper body to fall down, and the fragile spine cannot withstand the strong impact of the ground, resulting in high vertebral fractures, high paraplegia, and even death. Therefore, through a survey of 126 rhythmic gymnasts who participated in the 2011 “China Art Sports Cup” China Rhythmic Gymnastics Championship, a total of 172 injuries were found in 136 gymnasts, and the injury risk analysis was carried out from the main characteristics of the injuries.
Designing a Multiobjective Human Resource Scheduling Model Using the Tabu Search Algorithm
Authors: Mirataollahi olya Roghayeh , Shayannia Seyed Ahmad , Mehdi movahedi Mohammad
Published: June 2022

Nowadays, the major and substantial challenge and constraint of organizations, specifically in developing countries, are not the lack of raw materials, energy, or even technology but cases that are directly or indirectly associated with human resource management. The most significant problems that organizations face include dissatisfaction, lack of motivation, inefficiency of human resources, high amount of job turnovers, and low productivity. Today’s organizations and institutions should realize true perfection and health create the conditions for survival, order, excellence, and growth. In this research, considering the high importance of these issues, the problems of scheduling and allocation of manpower in a real place are solved. To this end, the metaheuristic Tabu search algorithm is used with the aim of minimizing the duration of activity and the presence of all manpower. For this purpose, to achieve the objectives of the research, three different scenarios related to the required manpower and the minimum‐maximum presence of manpower according to whether they are on leave or not are used.
The Application of Multi-Source Big Data Mining Techniques in the Analysis of Basketball Economic Management
Authors: Liang Hui
Published: June 2022

In recent years, China has been paying more and more attention to the development of the sports industry, and many sports are no longer seen as a mere sport, but can be developed into an industry and play an important role in the development of the economy. This paper examines the application of multi-source big data mining techniques in the analysis of basketball economic management. Firstly, through multi-source big data mining technology, we collect various factors that influence the development of basketball economic industrialization, use Hash Tree-based Apriori algorithm to mine various influencing factors for basketball economic industrialization, and analyze the correlation between each influencing factor. The association rule mining results are then used to analyze the relationship between the key influencing factors and the industrialization of the basketball economy. This paper examines various aspects of the Chinese basketball league market, including the management system, market operations, and talent flow, and compares them with the foreign basketball industry models, in order to analyze the operation of China’s basketball industrialization and develop corresponding countermeasures to improve basketball economic management based on the results of the study.
[Retracted] A Study of the Political Culture of the Ming and Qing Agribusiness Societies under the Imperial Environment
Authors: Yuan Guiling
Published: June 2022

In the Ming and Qing dynasties, while the social life, economic structure, and even cultural atmosphere underwent profound changes, the dominant aspect of political culture was still deduced along the traditional track of the imperial system. The prominent characteristics of China's social form in the Ming and Qing dynasties are the development of the commercial economy and the enhancement of social freedom; the developed trend of common people’s culture; and the sustainable development of the centralized monarch‐bureaucratic‐aristocratic system, which constitute a self‐consistent pattern. This paper on the political culture of political spirit, political value, political thought, the four dimensions, the specific period, specific social community, public power setting and operation, and the perspective of the Ming and Qing social form of political culture, this study helps people to the imperial environment of Ming and Qing rural political culture and understanding and exploration.
Efficacy and Safety Evaluation of Intramedullary Nail and Locking Compression Plate in the Treatment of Humeral Shaft Fractures: A Systematic Review and Meta-analysis
Authors: Hu Yong , Wu Tianhui , Li Baolin , Huang Yongxiang , Huang Changqiang , Luo Yilin
Published: June 2022

Objective. The surgical treatment scheme of humeral shaft fracture is still controversial with no consensus reached. This meta-analysis was aimed at comparing the efficacy and safety of intramedullary nail (IMN) and locking compression plate (LCP) in the treatment of humeral shaft fractures. Methods. PubMed, Medline, Embase, Ovid, Cochrane Library, ISI Web of Science, Clinical Trials, and Chinese databases, including China National Knowledge Infrastructure Project, Wanfang database, and China biomedical abstracts database, were used to search the literature. Review Manager software was employed for statistical analysis and establishing forest and funnel maps. Categorical variables were measured by relative risk (RR), and standardized mean difference (SMD) was used to measure continuous variables. 95% confidence intervals were used for each variable. The modified Jadad scale, Newcastle-Ottawa scale, and Cochrane’s bias risk tools were used to evaluate the bias and risk of eligible studies. Results. A total of 14 studies were included in the analysis with a total of 903 patients with humeral shaft fracture. Significant differences with regard to operation time (

Std
=
−
1.18

, 95% CI: -2.14, -0.22,

Z
=
2.41

,

P
=
0.02

), blood loss (

Std
=
−
2.97

, 95% CI: -4.32, -1.63,

Z
=
4.34

,

P
<
0.001

), and postoperative infection rate (

RR
=
0.32

, 95% CI: -0.15, 0.68,

Z
=
2.98

,

P
=
0.003

) were noted between the IMN group and LCP group. In addition, the American Shoulder and Elbow Surgeon (ASES) score (

Std
=
−
0.22

, 95% CI: -0.44, 0.01,

Z
=
2.08

,

P
=
0.04

) and the rate of shoulder and elbow function limitation (

RR
=
1.88

, 95% CI: 1.06, 3.33,

Z
=
2.17

,

P
=
0.03

) between the 2 groups were also statistically significant. There were no significant differences in the rate of radial nerve injury, nonunion, delayed healing, and secondary operation between the two groups. Conclusion. IMN is superior than the LCP in terms of the operation time, intraoperative bleeding, and postoperative infection, suggesting its superiority in the humeral shaft fracture fixation. However, IMN is inferior to LCP in ASES score and shoulder elbow function limitation rate, indicating poor early postoperative functional recovery. More studies are required to evaluate and analyze the clinical efficacy between IMN and LCP regarding long-term function after artificial graft removal.
Effects of Serum LDL-C, CysC, and D-D in Patients with Coronary Atherosclerotic Heart Disease
Authors: Shen Chaofeng , Wang Jing , Tu Sijia
Published: June 2022

Objective. To investigate the effects of low-density lipoprotein cholesterol (LDL-C) and serum cystatin C (CysC) combined with D-dimer (D-D) on patients with coronary atherosclerotic heart disease (CHD). Methods. 90 patients with CHD who were admitted to our hospital and diagnosed by coronary angiography (CAG) from February 2020 to June 2021 were selected as the study subjects. 90 patients were grouped according to different types and branches of coronary lesions, and 30 patients with outpatient health check-ups at the same period were selected as the control group, and the differences in serum LDL-C, CysC, and D-D levels between the groups were compared. The logistic regression model was built to explore risk factors affecting the occurrence of CHD. Also, receiver operating characteristic (ROC) curves were drawn to analyze the diagnostic value of LDL-C, CysC, and D-D in CHD. Results. In the comparison of LDL-C, CysC, and D-D levels, CHD group > control group (

P
<
0.05

); stable angina (SAP) group > unstable angina (UAP) group > acute myocardial infarction (AMI) group (

P
<
0.05

); three-branch group > two-branch group > single-branch group (

P
<
0.05

). The logistic regression model showed that high expression levels of LDL-C, CysC, and D-D, male gender, and combined hypertension were risk factors for CHD. The area under the curve (AUC) of the combination of LDL-C, CysC, and D-D was 0.868, and the sensitivity and specificity were 88.89% and 73.33%, respectively, which are higher than those in single diagnosis (

P
<
0.05

). Conclusions. LDL-C, CysC, and D-D are highly expressed in CHD samples, and the combination of the three is beneficial to enhance the diagnostic accuracy of clinical CHD.
Cocompetitive Characteristics and Quantitative Design of Engineering Parameters for Coal Gas Predrainage Boreholes
Authors: Xia Tong-qiang , He Jiao-fei , Li Zi-long , Sun Xiao-yan , Sun Dun-shuai , Lu Jian-hang , Cui Hao-jie
Published: June 2022

Quantitative design of the optimal gas extraction engineering parameters has always been a key scientific problem to meet the predrainage target of the coal seam, which is paid great attention to and urgently expected to solve for the gas extraction engineering of coal mine. In this paper, the governing equation of the evolution of coal seam gas content is established under the interference and cooperation of gas extraction by boreholes, and the calculation formula of gas cooperative efficiency is defined. Based on gas-air mixed flow, a multifield coupling 3d model of coal gas extraction using boreholes was developed. The content, method, and principle of optimal spacing parameter design of extraction borehole were proposed, and the constraint conditions and objective function of optimal design were constructed. The flow characteristics of gas extraction using boreholes in the coal seam area and the influence of different parameters on gas extraction effect are studied. The cooperative and competitive behaviors of gas extraction by boreholes in coal seam are revealed. The results show that borehole spacing, seam fracture permeability, and gas adsorption constant have significant effects on the synergistic and competitive effects of gas extraction, while the negative pressure of gas extraction and coal matrix permeability have little effects, but the negative pressure of gas extraction has great effects on gas extraction concentration. Finally, Comsol With Matlab is used to solve the multiconstraint nonlinear optimization problem of gas drainage engineering parameters along coal seam in 18401 working face of Tunlan Coal Mine. The effect of actual gas extraction investigation is very remarkable, which provides a quantitative calculation basis for scientific gas extraction in coal mine.
A Multi-attribute Two-Sided Matching Decision Method Based on Multi-granularity Probabilistic Linguistic MARCOS
Authors: Lu Jiali , Ni Jing
Published: June 2022

With the complexity of the matching environment, individual differences in matching objects and the uncertainty of evaluation information should be considered. The probabilistic linguistic term set (PLTS) is a useful tool to describe the uncertainty and limited cognition of matching objects. Thus, this paper proposes a multi-attribute two-sided matching method based on multi-granularity probabilistic linguistic MARCOS. First, we use a probabilistic linguistic term set with different granularities to express the evaluation information of different matching objects. Then, a conversion function is used to unify different granularity probabilistic linguistic terms. Second, a linguistic scale function is introduced to improve the expectation function, deviation degree, and distance of PLTS. The processed probabilistic linguistic evaluation information is transformed into accurate utility values through the transformation function. The evaluation attribute weights are determined by PLTS distance entropy. Based on this, this paper proposes a multi-granularity probabilistic linguistic MARCOS method to obtain the two-sided satisfaction degree. Finally, an optimization model which aims to maximize the overall satisfaction degree of matching objects by considering the stable matching condition is then established and solved to determine the matching between matching objects. The multi-objective two-sided matching model is constructed with the objective of maximizing the two-sided satisfaction degree. A case study of the service outsourcing matching is presented to validate the proposed method. The comparative analyses and discussions are also provided to demonstrate its effectiveness and scientific character.
Performance of PBL-Based Image Teaching in Clinical Emergency Teaching
Authors: Xu Hao , Li Qian , Xie Donghui , Wang Jingjing , Zhang Min
Published: June 2022

At present, with the rapid increase of emergency knowledge and the improvement of people’s requirements for medical quality, the traditional teaching mode cannot fully meet the needs of emergency teaching in the new era. This paper is aimed at improving the clinical emergency teaching mode by problem based learning (PBL) teaching method and improving the comprehensive ability of clinical emergency of medical students. This article proposes a problem-based PBL imaging teaching method, combining the characteristics and content of clinical emergency courses, focusing on students, highlighting the problem-solving process, and improving students’ creative thinking ability. To cultivate students’ interest in clinical learning, develop their self-learning ability, train their teamwork and communication skills, and cultivate their ability to set, question, and solve questions, so as to promote medical students’ overall comprehensive ability to integrate specialized knowledge and clinical practice. In this paper, the PBL teaching method and the traditional teaching method of comparative experiments show that the PBL teaching method can more effectively highlight the characteristics of clinical emergency medicine teaching mode and make full use of the limited emergency teaching resources, so as to improve the quality of clinical emergency teaching. Compared with the traditional teaching mode, the theoretical knowledge and clinical operation skills of medical students under the PBL teaching mode are improved by 13%. Autonomous learning ability, communication ability, and creative thinking ability have also been relatively improved.
In Vitro Anthelmintic Activity and Phytochemical Screening of Crude Extracts of Three Medicinal Plants against Haemonchus Contortus in Sheep at Haramaya Municipal Abattoir, Eastern Hararghe
Authors: Mumed Hassen Shamil , Nigussie Dereje Regassa , Musa Kedir Sali , Demissie Abdallahi Abdurahman
Published: June 2022

The current study was carried out to evaluate the anthelmintic efficacy of crude methanolic extracts of leaves of Croton macrostachyus and Nicotiana tabacum and rhizome parts of Zingiber officinale on nematode parasite, Haemonchus contortus. For these objectives, adult worm mortality assay (AWMA) was conducted on adult H. contortus to investigate the in vitro adulticidal effect of crude extracts from March to October 2021 G.C. The percentage yield of crude 99.9% methanolic extracts was 53%, 78%, and 44% for C. macrostachyus, N. tabacum, and Z. officinale, respectively. Phytochemical analysis using standard techniques was also used to detect secondary metabolites contained in the plants. The study revealed the presence of secondary metabolites such as tannins, flavonoids, steroids, and terpenoids in all extracts, which are considered to be the chemical components that are responsible for the wide therapeutic activities of several medicinal plants. In in vitro study, four graded concentrations of the crude extracts (500 mg/ml, 250 mg/ml, 125 mg/ml, and 62.5 mg/ml) were tested at regular time intervals, and parasite viability for 8 hours was recorded in triplicate. Albendazole (1.25 mg/ml) and distilled water were used as the positive and negative controls, respectively. At 4 hr posttreatment, the 62.5 mg/ml, 125 mg/ml, and 250 mg/ml concentrations of C. macrostachyus, N. tabacum, and Z. officinale extracts have caused significantly higher mortality (

P
<
0.05

) compared to the albendazole. Methanolic extracts of C. macrostachyus, N. tabacum, and Z. officinale produced mortality of adult H. contortus significantly (

P
<
0.05

) to the level of 93%, 83%, and 50% at concentration of 125 mg/ml at 4 hr posttreatment and meanwhile at 6 hr produced 100%, 100%, and 90%, respectively, at the same concentration. On the other hand, albendazole (1.25 mg/ml) killed 60% and 80% of the parasites at 4 hr and 6 hr posttreatment, respectively. Concentrations of all the extracts had showed a comparable and strong nematocidal effect on H. contortus having no significant difference with that of the positive control (

P
>
0.05

) at 8 hr posttreatment period. Hence, the current study revealed that the extracts from three plants have potential anthelmintic effect, and we recommend further study on fractionating each component separately and validating the materials using other parasite developmental stages are warranted.
Research on Image Texture Feature Extraction Based on Digital Twin
Authors: Li Juan
Published: June 2022

The purpose of image smoothing is to improve the visual effect of the image and improve the clarity of the image, so as to make the image more conducive to computer processing and various feature analysis. Because the current technology fails to smooth the preprocessed image, it leads to the extraction of image texture features. The anti-interference performance is weak. For this reason, an image texture feature extraction technology based on the digital twin is proposed. Similarity analysis is carried out through the internal structure of the image, and the image is smoothed by the semisupervised learning method. On the basis of optimizing the denoised image through digital twinning, detect target feature points in the original image, then remove the abnormal and split feature points, assign the direction of image texture feature points, and build a fuzzy back propagation neural network model. Image texture feature extraction technology is implemented. The experimental results show that, compared with the traditional method, the proposed technique has a strong identification of original image features, and has a strong consistency with original data, and has a strong ability to resist the influence of abnormal data, noise, or redundant feature points.
Application of Industrial Big Data Cloud Control Platform Based on Fusion Transmission Sensor
Authors: Meng Weiping , Shao Wenxin
Published: June 2022

In order to solve the problem that the traditional operation and maintenance system of photovoltaic operation and power station is mainly based on statistical analysis and multisite and multilevel deployment mode, which wastes software and hardware resources, is not easy to expand and has extremely low efficiency, which cannot meet the urgent needs of users to reduce costs and increase efficiency. This research proposes a methodology for integrating big data, cloud computing, and photovoltaic operation and maintenance. This method constructs the business model, data model, application model, and technical model of the photovoltaic power station operation and maintenance cloud platform. The results obtained are as follows: the system provides diagnostic services for the application system of a 30 MWp photovoltaic power station in a certain place, and a total of 87 defects are found, the defect elimination rate is 88.51%, and the monthly power generation of the power station is increased by 122,529 kWh; the use effect of the system in this research after it goes online. The evaluation is 93.04 points, ranging from very satisfactory (A) to satisfactory (B) and biased towards A, indicating that the use effect is good. It is proved that the successful research and promotion of the system in this research will be of great significance to improve the intelligent operation and maintenance level of photovoltaic power plants and improve the operation and maintenance efficiency of photovoltaic power plants.
Clinical Characteristics of Metastatic Colorectal Cancer Combined with Gastrointestinal Perforation and Prognostic Value of Circulating Tumor DNA
Authors: Yang Hong , Rong Dongwen , Yang Wenhui
Published: June 2022

Objective. To explore the clinical characteristics of metastatic colorectal cancer combined with gastrointestinal perforation and the prognostic value of circulating tumor DNA (ctDNA). Methods. A total of 97 patients with metastatic colorectal cancer and gastrointestinal perforation were enrolled as the research objects between February 2016 and January 2019. Their clinicopathological characteristics were statistically analyzed. Patients were divided into the death group (n = 78) and the survival group (n = 19) according to their survival status at 3 years after surgery. The ctDNA level between the two groups was compared. Also, its evaluation value on patient prognosis was analyzed. The survival time in patients with different levels of ctDNA was compared. Results. The clinical staging was stage T4 in patients with metastatic colorectal cancer combined with gastrointestinal perforation, including 70 cases (72.16%) aged ≥60 years and 27 cases (27.84%) <60 years. There were 61 males (62.89%) and 36 females (37.11%). There were 27 cases (27.84%) with primary site at left colon, 59 cases (60.82%) at right colon and 11 cases (11.34%) at rectum. There were 56 cases (57.73%) with number of metastatic organs ≥2 and 41 cases (42.27%) <2. There were 58 cases (59.79%) treated with VEGF inhibitor before perforation, 40 cases (41.24%) with lung metastasis, 72 cases (74.23%) with liver metastasis, 30 cases (30.93%) with pelvic metastasis, 24 cases (24.74%) with distant lymph node metastasis, 56 cases (57.73%) with obstruction, and 35 cases (36.08%) with diverticulum. According to survival status at 3 years after after surgery, patients were divided into the death group (n = 78) and the survival group (n = 19). The level of plasma ctDNA in the death group was higher than that in the survival group (

P
<
0.05

). The area under curve (AUC) of ctDNA for predicting survival of patients was 0.806. According to ctDNA expression, patients were divided into the high expression group (n = 57) and the low expression group (n = 40). The survival rate in the high expression group was lower than that in the low expression group (7.02% (4/57) vs 36.38% (15/40)) (

P
<
0.001

). The median survival time for the two groups was 18.20 and 28.10 months, respectively. Conclusion. Clinical characteristics of metastatic colorectal cancer combined with gastrointestinal perforation include elderly age, obstruction, and diverticulum. The expression of ctDNA has evaluation value for prognosis of patients.
Single Phytoplankton Species Growth with Nonlocal Crowding Effect Caused by Chemosensory Aggregation in a Water Column
Authors: Wang Yan , Wang Jinxiang , Yao Xiaobin
Published: June 2022

In this paper, we study the existence of positive steady states for a nonlocal reaction‐diffusion model which describes the growth of a single phytoplankton species with nonlocal crowding effect caused by chemosensory aggregation in a water column. Our result shows that under some conditions, the nonlocal crowding effect is effective to the existence of steady states of phytoplankton populations. Based on a key boundedness Lemma, the main result is proved by fixed point index theory and some analytical techniques.
Association Between Serum Afamin Levels with Nonalcoholic Associated Fatty Liver Disease
Authors: Chen Shenghui , Liu Zhening , Cen Li , Wang Jinghua , Zhang Juanwen , Zhang Xiaofeng , Xu Chengfu
Published: June 2022

Afamin is a member of the hepatokine that are strongly associated with various metabolic diseases. The relationship between afamin and nonalcoholic fatty liver disease (NAFLD) remains unclear. This study aimed to explore the correlation between serum afamin levels and NAFLD. We analyzed 88 NAFLD patients and 88 age- and sex-matched healthy controls who took their health examinations at the First Affiliated Hospital, Zhejiang University School of Medicine. The association was further confirmed in 22 biopsy-confirmed NAFLD patients and 36 healthy controls. Serum afamin levels were evaluated using an enzyme-linked immunosorbent assay (ELISA). NAFLD patients had significantly higher serum afamin levels than the healthy controls (14.79 ± 5.04 mg/L versus 10.83 ± 3.24 mg/L;

P
<
0.001

). Serum afamin levels were positively correlated with metabolic parameters including the body mass index, waist circumference, systolic blood pressure, liver enzymes, and lipid profiles. A multiple regression analysis showed that serum afamin levels were independently related to the risk of NAFLD (OR: 1.289, 95% CI, 1.141–1.456;

P
<
0.001

). The receiver operating characteristic (ROC) analysis showed that the area under curve (AUC) of serum afamin plus the BMI for detecting NAFLD was 0.878. In participants with liver biopsies, the serum afamin plus the BMI detected NAFLD with an AUC of 0.758. In conclusion, serum afamin levels were positively associated with prevalence and risk of NAFLD, and serum afamin plus the BMI had a high diagnostic performance for NAFLD. This study provides epidemiological evidence of afamin in NAFLD.
Optimizing Resource‐Constrained Project Scheduling Problem considering the Reliability Function
Authors: Naderi Saeideh , Vaez-Ghasemi Mohsen , Movahedi Sobhani Farzad
Published: June 2022

Resource‐constrained project scheduling has been a significant and practical problem in recent decades. In this research, besides previous assumptions and models regarding scheduling, the reliability function with a novel approach is included in the model. A new look at the project scheduling problem is pursued by studying the probability of access to renewable resources. The mentioned problem programming model is a mixed nonlinear mathematical model that uses the properties of an exponential function to become a linear programming model, exact optimization software is used to solve it in smaller dimensions, and a genetic algorithm is used to solve it in NP‐hard dimensions. The algorithms and statistical analysis results at a 95% confidence level show the proper performance of the genetic algorithm; therefore, this algorithm is more efficient for the proposed model. Using the provided mathematical model, this research leads to decreasing time and lags, decreasing costs, and increasing reliability in multimode activities.
Development and Evaluation of a Novel Polymer Drug Delivery System Using Cromolyn-Polyamides-Disulfide using Response Surface Design
Authors: Alkurdi Nadeen Mohammad , Hussein-Al-Ali Samer Hasan , Albalwi Awad , Haddad Mike Kh. , Aldalahmed Yousef , Ali Dalia Khalil
Published: June 2022

The aim of this study was to employ nanoparticles as drug carriers. The research involved the design of cromolyn polyamide-disulfide nanocomposites to overcome the problem of frequent cromolyn doses and improve their properties. The cromolyn polyamide-disulfide samples were prepared using several amounts of cromolyn and sodium polyamide-disulfide polymer at different pH values. Analysis of variance (ANOVA) was performed to obtain the significant independent variables affecting the dependent response by using a

P

value lower than 0.05. The nanocomposites produced were characterized using Fourier transform infrared (FTIR) spectroscopy and in vitro release. An FTIR test was used to evaluate the functional groups of cromolyn in nanocomposites, which indicated that the drug was encapsulated inside the polymer. All data indicated the presence of cromolyn in the nanocomposites. The release profile of nanocomposites was found to be sustained. Therefore, the outcome of this research project could be a starting point for further work to optimize and assess polyamide-disulfide polymers for delivering another drug.
Design and Optimization of Working Parts of Vertical Spiral Ditching Machine Based on Milling Force and BP Neural Network Model
Authors: Chen Guo
Published: June 2022

The existing vertical spiral ditching machine mainly works in flat orchards, and the structural design of ditching components does not match the design of power transmission system, which leads to high ditching power consumption and poor ditching stability. According to the needs of deep application of organic fertilizer in orchards, a spiral cutter was designed to alleviate the common problems of high power consumption and poor stability of ditching machine and reduce the power consumption of ditch cutting. Therefore, the motion parameters and structural parameters of the spiral cutter are optimized. Using ANSYS preprocessor, the finite element model of cutting soil with spiral cutter is established, and the implicit functional relationship between milling force factor and instantaneous cutting thickness is established by using BPNN (BP neural network). On the basis of the established prediction model of milling force, orthogonal experiments were carried out to obtain the best combination of cutter head rotation speed, slotting depth, and advancing speed with minimum power consumption: 20.16 rad/s, 0.3 m, and 0.12 m/s. By investigating the influence of various working parameters on the power consumption of ditching machine, the analysis basis is provided for selecting reasonable working parameters of ditching machine.
Monitoring Mycoplasma pneumoniae-Specific Antibody, C-Reactive Protein, and Procalcitonin Levels in Children with Mycoplasma Pneumonia Is Important
Authors: Cao Xinying
Published: June 2022

The goal of this study was to see how important it is to monitor Mycoplasma pneumoniae-specific antibody IgM, C-reactive protein, and procalcitonin levels in the blood of kids with Mycoplasma pneumoniae pneumonia as a reference for clinical diagnosis and treatment. The study group consisted of 96 children who had mycoplasma pneumonia in our hospital between May 2020 and May 2021, and the control group consisted of 96 healthy children who had a routine physical examination in our hospital at the same time. C-reactive protein and procalcitonin were measured and compared. The application value of single detection and combined detection of Mycoplasma pneumoniae-specific antibody IgM, C-reactive protein, and procalcitonin in the diagnosis of Mycoplasma pneumoniae pneumonia was evaluated based on clinical diagnosis results. The detection values of C-reactive protein and procalcitonin in the study group were higher than those in the recovery period and the control group,

P
<
0.05

; the detection values of C-reactive protein and procalcitonin in the study group were higher than those in the control group,

P
<
0.05

. The combination detection of Mycoplasma pneumoniae-specific antibody IgM, C-reactive protein, and procalcitonin had a greater diagnostic accuracy than single detection (

P
<
0.05

). The sensitivity was higher than C-reactive protein and procalcitonin (

P
<
0.05

); the specificity and positive predictive value were higher than Mycoplasma pneumoniae-specific antibody IgM (

P
<
0.05

); and the negative predictive value was higher than procalcitonin (

P
<
0.05

). The clinical value of combining the detection of Mycoplasma pneumoniae-specific antibody IgM, C-reactive protein, and procalcitonin in the diagnosis of Mycoplasma pneumoniae pneumonia in children is higher than that of single item detection, and it can provide a reliable clinical reference, as well as aid in evaluating the recovery effect of children, and it is worthy of application.
Self-Adaptation Resource Allocation for Continuous Offloading Tasks in Pervasive Computing
Authors: Ehsan Aiman , Haider Khurram Zeeshan , Faisal Shahla , Zahid Faisal Maqbool , Wangari Isaac Mwangi
Published: June 2022

Advancement in technology has led to an increase in data. Consequently, techniques such as deep learning and artificial intelligence which are used in deciphering data are increasingly becoming popular. Further, advancement in technology does increase user expectations on devices, including consumer interfaces such as mobile apps, virtual environments, or popular software systems. As a result, power from the battery is consumed fast as it is used in providing high definition display as well as in charging the sensors of the devices. Low latency requires more power consumption in certain conditions. Cloud computing improves the computational difficulties of smart devices with offloading. By optimizing the device’s parameters to make it easier to find optimal decisions for offloading tasks, using a metaheuristic algorithm to transfer the data or offload the task, cloud computing makes it easier. In cloud servers, we offload the tasks and limit their resources by simulating them in a virtual environment. Then we check resource parameters and compare them using metaheuristic algorithms. When comparing the default algorithm FCFS to ACO or PSO, we find that PSO has less battery or makespan time compared to FCFS or ACO. The energy consumption of devices is reduced if their resources are offloaded, so we compare the results of metaheuristic algorithms to find less battery usage or makespan time, resulting in the PSO increasing battery life or making the system more efficient.
A Comparative Study of Xi’s Tendon Gangrene (Nonischemic Type of Diabetic Foot) and Gangrene (Diabetic Foot Ischemic Type)
Authors: Peng Linfeng , Wang Yuzheng , Zhao Cheng , Zhao Zhiguo , Fei Qi , Xin Pengchao , Xu Hongtao , Cao Yemin
Published: June 2022

Background. Diabetic foot gangrene refers to a lesion in which the tissue of the foot or lower extremities of diabetic patients is damaged, and the cause is the infection of peripheral blood vessels and neuropathy caused by diabetes. Objective. To compare the related indexes of blood glucose, inflammation, blood viscosity, and peripheral neuropathy between the nonischemic diabetic foot and ischemic diabetic foot, the same and different characteristics of the two different types of diabetic foot in pathogenesis were discussed and studied. Methods. A total of 122 patients with diabetic foot were selected from the Department of Vascular Medicine, Shanghai Hospital of Integrated Traditional Chinese and Western Medicine, including 61 cases of ischemic type and 61 cases of nonischemic type. The differences in blood glucose, inflammation, blood supply, and peripheral neuropathy between the nonischemic diabetic foot and ischemic diabetic foot were compared to explore their different characteristics. Results. The blood glucose index, inflammatory index, and plasma fibrinogen in patients with nonischemic diabetic foot were significantly higher than those in patients with ischemic diabetic foot (

P
<
0.05

). The patients with ischemic diabetic foot were higher in age and blood lipid index than those with the nonischemic diabetic foot (

P
<
0.05

), while having no significant difference in platelet count, plasma viscosity, hematocrit, and end products of glycation (AGEs). Conclusion. The nonischemic diabetic foot is mainly infective necrosis, and the ischemic type is ischemic necrosis. The former occurs in the middle-aged and elderly with good blood supply between 40 and 60 years old, while the latter occurs in the elderly with the severe vascular disease over 60 years old. The blood glucose level of nonischemic patients is significantly higher than that of ischemic patients, but it has little to do with the course of diabetes.
Quality Effort Strategy of O2O Takeout Service Supply Chain under Three Operation Modes
Authors: Xing Peng , Yao Junzhu , Wang Meixia
Published: June 2022

This paper investigates channel selection and quality effort in O2O takeout service supply chain consisting of a takeout platform, a catering business, and a distribution rider. By analyzing the three operation modes of platform distribution, business self‐distribution, and business self‐built platform + distribution, the profit functions of O2O takeout service supply chain members are constructed, respectively. On the basis of game theory, the optimal quality effort and profits are obtained. Combined with numerical simulation, the effects of revenue sharing rate and market size on the optimal quality effort and profits under different scenarios are discussed. The results reveal that O2O takeout platform should cooperate with more catering businesses, and adopt appropriate strategies considering different market sizes of catering businesses. Additionally, the catering business should properly consider the market size and adopt different online and offline prices. Meanwhile, the rider should choose a reasonable quality effort according to the revenue sharing rate.
Nanotube Combined with Roller Skater Rehabilitation Therapy in the Treatment of Knee Arthritis
Authors: Sun Peng
Published: June 2022

As a kind of nanotechnology, nanomaterials have made great progress in recent years, among which nanotube is one of the most representative new nanomaterials. Knee arthritis, as a degenerative bone disease, often occurs in the elderly. According to statistics, the incidence of knee arthritis in China is between 3 and 15 percent, among which the incidence of the elderly over 65 years old is as high as 68 percent. The purpose of this study is to explore the application effect of the rehabilitation therapy of nanotube combined with roller skater in the treatment of knee arthritis and promote the continuous improvement of clinical treatment effect of knee joint. In this study, by comparing the curative effect of the roller skates combined with nanotubes in the rehabilitation treatment group and the control group, the clinical treatment effects of the two groups were comprehensively evaluated and evaluating the comprehensive effects of nanotubes combined with roller skates from various angles of a comprehensive role of rehabilitation therapy in the treatment of knee osteoarthritis, to give full play to the advantages of nanotubes and rehabilitation therapy, promote the continuous improvement of treatment, and provide important guidance for the clinical treatment of knee arthritis, thereby improving the therapeutic effect. The results showed that the total effective dose was 82.61% in the control group and 97.83% in the observation group. Before and after the treatment, the therapeutic effect of the nanotube drug treatment group was improved by about 40%, and the therapeutic effect of the observation group of rehabilitation therapy with nanotube combined wheel athletes was increased by about 42%. It indicates that compared with the single treatment, the rehabilitation therapy of the nanotube combined with roller skater greatly improves the therapeutic effect of knee arthritis.
Effectiveness of Quantitative Shear Wave Elastography for the Prediction of Axillary Lymph Node Metastasis
Authors: Cheng Yingying , Li Guofu , Jing Hui , Yuan Shasha , Zhang Lei , Cheng Wen
Published: June 2022

Objective. Invasive breast cancer can be metastasized through axillary lymph nodes (LNs). This study was to evaluate the effectiveness of quantitative shear wave elastography (SWE) to predict axillary LN metastasis, which also provides prognostic implication of SWE as a histopathologic element of invasive breast cancer. Methods. 72 prospectively enrolled patients received B-mode ultrasound (BUS) and SWE, and the elasticity index (EI) of SWE at the stiffest part of lymph nodes (LNs) was measured. EI of SWE was closely associated with pathologic results and the histopathologic elements. The receiver operating characteristics (ROC) curve was drawn to evaluate the optimal cut-off value for the assessment of disease severity. Results. A significantly longer short-axis diameter and a larger maximal cortex were observed in malignant LNs than that in healthy LNs. The absence of the hilum was associated with metastatic LNs. The EI of SWE varied markedly between the benign and malignant LNs. The combination of Emax and BUS showed higher area under the curve (AUC) than BUS alone to predict metastatic LNs (0.7762 vs. 0.7230). EI of SWE in malignant lymph nodes those with extranodal extension are higher than those without extranodal extension. Conclusions. Quantitative SWE provides a viable alternative for the assessment of axillary LN and shows great potential to predict pathological prognostic elements of metastatic axillary LNs in invasive breast cancer. Joint use of SWE and BUS allows examination of the predictive outcome of BUS for axillary lymph node metastasis in invasive breast cancer.
Salt Spray Corrosion of 2060-T8 Al–Li Alloy in an Aggressive Environment
Authors: Zhang Zhengquan , Wang Yuling , Liangfeng Li
Published: June 2022

The phase and microstructure of corrosion product formed on 2060-T8 Al–Li alloy have been investigated effectively by SEM and XRD after salt spray corrosion. It was found that the corrosion product growth rate can be divided into three stages: the main phases of corrosion product were Al2O3, Al(OH)3, and AlOOH phases; as the increasing of salt spray time, the phase angle of A12O3 shifts slightly to the left at 31.8°; and the phase angle of A12O3 first shifts to the left, then to the right at 38.6°. The formation and evolution model of salt spray droplet was built, and the formation mechanism of corrosion product was also analyzed. This alloy shows a sensitive corrosion performance to the salt spray environment.
Research on Image Recognition of Gymnastics Sports Injuries Based on Deep Learning
Authors: Jia Peng , Xu Yixiong
Published: June 2022

Gymnastics is an increasingly popular sport and an important event in the Olympic Games. However, the number of unavoidable injuries in sports is also increasing, and the treatment after the injury is very important. We reduce the harm caused by the injury through the identification and research of pictures. Image preprocessing and other methods can in-depth learn about gymnastics sports injuries. We identify the injured pictures of athletes to know the injury situation. Through the analysis of the force of the athletes during exercise, they can be better integrated into picture recognition for sports injuries. More appropriate prevention and treatment measures are suggested.