bluuebunny/crossref_metadata_2025 huggingface dataset:
Recent Advancement in Goat Nutrition
Authors: Matovu Jacob , Alçiçek Ahmet
Published: July 2021

Nutrition or feeding is one of the most important components in livestock production and it’s associated with high costs. In goat production, it can typically account for 60% or more of total production costs. As a result, there is much new research being conducted on goat feeding and nutrition in a variety of areas regarding production costs, sustainability, and quality of the product produced. Areas of research that are currently receiving much attention include feed additives such as prebiotics, probiotics, enzymes, antioxidants, plant secondary metabolites, etc. Their use in animal feed is expected to increase due to the abolition of synthetic antimicrobials in feed, although there is still limited information on their use and is accompanied by contradictory research reports. This study aims to highlight some of the recent and emerging studies on the different feed resources, feed additives and dietary feed composition for goats.
The Mediating Role of Mathematics Self-concept in the Association of Self-esteem and Classroom Environment Perceptions with Math Anxiety in Students
Authors: Naderi Dehsheykh Maasomeh , Hafezi Fariba , Dasht Bozorgi Zahra
Published: July 2021

Background: Math anxiety (MA) emerges as a state of discomfort and anxiety when a student is faced with a math problem. Objectives: The present study aimed to investigate the association between self-esteem and classroom environment perceptions with math anxiety through the mediating role of mathematics self-concept (MSC) in female high school students. Methods: This descriptive-correlational study was conducted on all the female high school students in Ahvaz, Iran in the academic year 2020 - 2021. In total, 237 students were selected as the sample population via single-stage cluster sampling. Data were collected using the Math Anxiety questionnaire (MAQ), Self-esteem questionnaire (SEQ), Dundee Ready Educational Environment measure (DREEM), and Mathematical Self-concept questionnaire (MSCQ). The proposed research model was evaluated using structural equation modeling. Results: With the exception of self-esteem and classroom environment perceptions (CEPs), all the direct paths were significantly correlated with MA (P = 0.001). Moreover, the indirect paths of self-esteem were significantly correlated with MA considering the mediating role of MSC (β = -0.240; P = 0.002). Furthermore, a significant association was observed between CEP and MA, mediated by MSC (β = -0.129; P = 0.001). Conclusions: According to the results, the proposed model had a good fit and could be an important step in identifying the influential factors in the MA of students.
The Association Between Severity of Dysmenorrhea and Social Support among Female Students of Ilam University of Medical Sciences
Authors: Mashreghi Mahsa , Suhrabi Zainab , Soliemanifard Parand , Farzi Sedigheh , Taheri Safoura
Published: July 2021

Background: Dysmenorrhea or painful menstruation is the most common periodic pain in women, which includes primary and secondary types. One of the possible factors affecting the severity of dysmenorrhea is the presence or absence of social support. Objectives: Due to the high prevalence of dysmenorrhea and its undesirable consequences on the quality of personal, social, and academic life of students, this study aimed to evaluate the association between severity of dysmenorrhea and social support among female students of Ilam University of Medical Sciences, Iran. Methods: Using purposeful sampling method, this cross-sectional and descriptive-analytical study was conducted on 286 female students of Ilam University of Medical Sciences (age range: 18 - 28 years) in 2018. Data collection tools included demographic information form, Visual Analogue Scale (VAS) to determine pain severity, and standardized Social Support Questionnaire (SSQ) to assess social support. Descriptive statistics (frequency and mean) and analytical statistics (Pearson’s correlation coefficient) were used for data analysis in SPSS software version 16. Results: The mean age of the samples was 21.62 ± 2.10 years, and the mean age of menarche was 13.57 ±1.33 years. The prevalence of primary dysmenorrhea was 86% among the samples, with 8% of them having low social support, 39.2% moderate social support, and 52.8% high social support. There was a significant association between social support and severity of dysmenorrhea so that Pearson’s correlation coefficient showed an inverse association between the two variables (r = -0.187, P = 0.002). Conclusions: The inverse association between the severity of dysmenorrhea and the level of social support highlighted the need for planning to create and enhance social support by family and community and reduce the effects that dysmenorrhea can have on physical, mental, and social health of individuals.
Two Refutations of the Vorhanden Reading of Heidegger’s Philosophy of Science in Being and Time
Authors: Goldberg Paul ,   Heidegger Circle
Published: July 2021

The dominant interpretation of Heidegger’s philosophy of science in Being and Time is that he defines science, or natural science, in terms of presence-at-hand (Vorhandenheit). I argue that this interpretation is false. I call this dominant view about Heidegger’s definition of science the vorhanden claim; interpreters who argue in favor of this claim I call vorhanden readers. In the essay, I reconstruct and then refute two major arguments for the vorhanden claim: respectively, I call them equipmental breakdown (Section 1) and theoretical assertion (Section 2). The equipmental breakdown argument, stemming mainly from Hubert Dreyfus, advances a vorhanden reading on the basis of three other interpretive claims: I call them, respectively, the primacy of practice claim, the decontextualization claim, and the breakdown claim. While I remain agnostic on the first claim, the argument fails because of decisive textual counterevidence to the latter two claims. Meanwhile, the theoretical assertion argument, which I reconstruct mainly from Robert Brandom, premises its vorhanden claim on the basis of some remarks in Being and Time indicating that theoretical assertions, as such, refer to present-at-hand things. Since science is taken to be a paradigmatic case of an activity that makes theoretical assertions, the vorhanden claim is supposed to follow. I refute this argument on the grounds that it equivocates on Heidegger’s concept of “theoretical assertion” and cannot account for his insistence that science does not principally consist in the production of such assertions. I conclude that, with the failure of these two arguments, the case for the vorhanden claim is severely weakened.
Earth and Planet
Authors: Johnson Rylie ,   Heidegger Circle
Published: July 2021

In light of the contemporary climate crisis, this paper argues that it is important to look at the distinction between earth and planet in Martin Heidegger confrontation with Ernst Jünger. To do so will point out an essential confrontation between earth and planet, revealing their respective essences. For Jünger, the global spread of technology is planetary in scale, which allows for the emergence of meaning through the figure of the worker. Heidegger, however, argues against the conception of the planet in favor of the earth, here rendered as the self-concealing withdrawal of the sensuous, which both makes possible and grounds planetary thinking. Insofar as art is that which indirectly reveals the earth, I will argue that Heidegger’s account of the origin of the artwork helps us to think against the planetary, and therefore against Jünger. I will conclude by presenting some reflections on the earth as a way of thinking the planetary catastrophe accompanying climate change.
The Potency of Open Objects
Authors: Schick Johannes F. M. ,   Philosophy Documentation Center
Published: July 2021

This essay researches the relation of the human being to technology in the Digital Age, employing the philosophies of Henri Bergson, Franco “Bifo” Berardi, and Gilbert Simondon. These conceptions allow for a critique of the quasi-religious belief in Singularity in the transhuman discourse of Artificial Intelligence and its underlying ontology. This ontology is based upon the belief that the world is predictable and computable. To develop a symmetrical relationship with technology in the digital age, I will argue for an ontological model of participation and novelty that conceives of living beings as constantly inventing and re-inventing new modes of being. Being human means to reinvents itself constantly by diachronically relating to its own contemporary condition as well as to the tool making origins of mankind. It implies that the technical objects have to be open in order to create a symmetrical relation with them.
Una representación náutica en una pizarra visigoda de la Dehesa del Castillo (Diego Álvaro, Ávila)
Authors: De Soto García María de los Reyes
Published: July 2021

El objetivo de este artículo es el análisis de una pizarra visigoda de dibujo hallada en las excavaciones practicadas en los años 40 del siglo XX en el yacimiento abulense de La Dehesa del Castillo (Diego Álvaro) por parte del Comisario Local de Excavaciones Arqueológicas, Arsenio Gutiérrez Palacios y que hasta el momento ha permanecido inédita. El estudio realizado sobre los elementos grabados ha permitido identificar un posible barco con sus tripulantes a bordo, elemento pocas veces representado sobre este tipo de materiales.
Numerical Optimization Methods for Ship Hydrodynamic Design
Authors: Campana Emilio F. , Peri Daniele , Tahara Yusuke , Kandasamy Manivannan , Stern Frederick
Published: July 2021

The use of computational methods in design engineering is growing rapidly at all stages of the design process, with the final goal of a substantial reduction of the cost and time for the development of a design. Simulations and optimization algorithms can be combined together into what is known as Simulation-Based Design (SBD) techniques. Using these tools the designers may find the minimum of some user defined objective functions with constraints, under the general mathematical framework of a Non-Linear Programming problem. There are problems of course: computational complexity, noise, robustness and accuracy of the numerical simulations, flexibility in the use of these tools; all these issues will have to be solved before the SBD methodology can become more widespread. In the paper, some derivative-based algorithms and methods are initially described, including efficient ways to compute the gradient of the objective function. Derivative-free methods - such as genetic algorithms and swarm methods are then described and compared on both algebraic tests and on hydrodynamic design problems. Both local and global hydrodynamic ship design optimization problems are addressed, defined in either a single- or a multi-objective formulation framework. Methods for reducing the computational expense are presented. Metamodels (or surrogated models) are a rigorous framework for optimizing expensive computer simulations through the use of inexpensive approximations of expensive analysis codes. The Variable Fidelity idea tries instead to alleviate the computational expense of relying exclusively on high-fidelity models by taking advantage of well-established engineering approximation concepts. Examples of real ship hydrodynamic design optimization cases are given, reporting results mostly collected through a series of projects funded by the Office of Naval Research. Whenever possible, an experimental check of the success of the optimization process is always advisable. Several examples of this testing activity are reported in the paper one is illustrated by the two pictures at the top of this page, which show the wave pattern close to the sonar dome of an Italian Navy Anti-Submarine Warfare corvette: left, the original design; right, the optimized one.
Ultimate Strength and Optimization of Aluminum Extrusions
Authors: Collette M. D. , Wang X. , Li J.
Published: July 2021

Recent large aluminum high-speed vessels have made use of custom extrusions to efficiently construct large flat structures including internal decks, wet decks, and side shell components. In this paper an efficient method for designing and optimizing such extrusions to minimize structural weight is presented. Strength methods for extrusions under in-plane and out-of-plane loads are briefly reviewed and shortcomings in existing aluminum strength prediction methods for marine design are discussed. A multi-objective optimizer using a genetic algorithm approach is presented; this optimizer was designed to quickly generate Pareto frontiers linking designs of minimum weight for a wide range of strength levels. The method was used to develop strength vs. weight Pareto frontiers for extruded panels for a main vehicle deck and a strength deck location on a nominal high-speed vessel.
Appendiceal intussusception
Authors: Ghidirim Gheorghe , Malcova Tatiana , Șor Elina , Mișin Igor
Published: July 2021

Appendiceal intussusception (AI) is an unusual and rarely reported clinical entity. It was first described by McKidd in a 7-year-old boy in 1858. Since then the literature on it has been confined to a few case reports and very small cases series, in totally about 300 cases being published. Because of variations of clinical symptoms and lack of pathognomonic sign, rarety of the pathology and diversity of causing factors, accurately detection of the presence or absence of appendiceal pathology is difficult. However, imagistic and endoscopic methods may be useful in AI detection and play a large and important role in differential diagnosis. Treatment of AI differs significantly depending on underlying pathological condition, benign or malignant.
The Emergency Hospital Bucharest to the Forefront of the Emergency Laparoscopic Surgery Development
Authors: Nicolau Alexandru Eugen
Published: July 2021

The use of laparoscopy in traumatic and non-traumatic abdominal surgical emergencies is unanimously accepted
due to the well-known advantages of minimally invasive surgery. In the period 1961-1966 in the Clinical Emergency
Hospital of Bucharest (CEHB) the first diagnostic laparoscopes were performed in the acute surgical abdomen,
respectively in the obstructive jaundice by dr. Gh.Popovici, respectively dr.C.Petrescu.In the modern era, the first
laparoscopic cholecystectomy was performed in 4 dec. 1993 by A.E.N.In 1994 the first laparoscopic
appendectomies, gynecological emergencies, exploration in traumatic abdominal contusion, followed by perforated
ulcer (1995), intestinal occlusion (1997), were performed. In the specialized literature, out of the 42 emergency
laparoscopy articles published in the journal “Chirurgia” (1994-2019), 16 (38,08%) belonged to the CEHB team, 11
of AEN. In 2004 the original monograph "Laparoscopic Emergency Surgery" appeared. Specialized chapters are
added in different volumes of surgical pathology.
At the Romanian Assocation of Endoscopic Surgery Congress (RAES) of 2008, the international participation
course “Laparoscopy in the acute abdomen” was organized. Since 2013, annual trauma workshops (DSTC ™) and
non-traumatic abdominal emergencies have been organized with international participation by CEHB, the surgery
clinic, and the UMFCarol Davila Department of Anatomy. CEHB surgeons presented papers at EAES,EATES and
ESTES congresses. Of the 1699 laparoscopic operations performed in the clinic in 2018, accounting for 31.27% of
the total operations, 493 (29.01%) were in emergency. The SCUB surgeons have had and have a major
contribution in preparing the residents, implementing and developing emergency laparoscopy within the
miniminvasive therapy, the therapy of the future.
Historical Trauma between Event and Ethics: Aleida Assmann’s Theory in the Context of Trauma Studies
Authors:   Saint Petersburg National Research University of Information Technologies, Mechanics and Optics University ITMO, Kapelchuk Kseniya ,   Sociological Institute of the Federal Center of Theoretical and Applied Sociology, Russian Academy of Sciences, St Petersburg, Russia
Published: July 2021

The paper focuses on the way the notion of trauma functions and is justified in the contemporary discourse on history. The author refers to the works of Aleida Assmann and examines the critique brought forward against memorial culture. Deconstructing Assmann’s argument, the author concludes that there are two levels of discourse that support and justify each other: the level of fact and the level of value. The first one deals with the problem of traumatic events and expanding memory about them, which is explained as a change of time regime. The second one deals with the ethical turn that made the change of the time regime possible. To analyse historical trauma, the article suggests breaking the connection between these two levels and examining their foundations separately.
Card Index of Former Latvian SSR KGB Agents: Trauma and the Path to Public Reconciliation
Authors:   Institute of Latvian History, University of Latvia, Latvia, Krēsliņš Uldis
Published: July 2021

In August 1991, the Republic of Latvia took over the documents of the former Latvian SSR KGB, including the card index of KGB agents. At that time, by postponing the card index publication, the political authorities made the issue of former KGB agents a hostage of their political interests. Discussion on the fate of the card index continued in Latvian public sphere over the next 27 years. The stance of the political elite, which found support in some groups of society, was opposed to the publication of the card index, being concerned about a possible witch-hunt and psychological trauma of the people mentioned in the card index as well as their relatives. However, as a result of public pressure, after lengthy indecision, the card index was made public in December 2018. Unfortunately, the publication of the card index has offered only a formal solution to the issue of the former KGB agents, and the expected results have been achieved from the aspect of neither historical truth nor public reconciliation. Only a small number of people mentioned in the card index have admitted the fact of their cooperation and just a few have expressed public regret. In turn, after 27 years of political elite’s hesitancy, most of the KGB persecution victims accepted the publication of the card index in silence. However, it is clear that denial and silence are not the way to public reconciliation and comprehension of trauma. Those few attempts to make one’s experience public show that in today’s situation people can seek reconciliation only with themselves and within themselves.
Maailma esimesed inimesed – Valgevene ja Eesti etioloogiad
Authors:   Department of the Ethnolinguistics and Folklore of the Centre for Belarusian Culture, Language and Literature Research at the National Academy of Sciences of Belarus, Boganeva Alena , Kõiva Mare ,   Department of Folkloristics, Estonian Literary Museum, Estonia
Published: July 2021

Belarusian and Estonian mythological and legendary narratives, especially aetiologies, share a number of similar motifs and characters, despite the fact that Estonian and Belarusian belong to different language families and share no common borders. However, some matches in the motifs are so complete and expressive that they, we believe, cannot be explained by typology or universals. Since the topic of ties between Estonian-Belarusian folklore is relatively unexplored, along with their historical contacts, the aim of this article is to point out the similarities in the motifs of Estonian and Belarusian legends regarding the first people in the context of Slavic and Finno-Ugric legends, as well as to represent some of the original Estonian and Belarusian aetiologies. The motives under examination are the recreation of humans, the skin of the nails, creation of a woman, the death of the first people, the motifs of the snake, eel, and weather loach, the cross of Christ, and others.
Väike-Abhaasia suured piiriküsimused
Authors:   School of Humanities, Tallinn University, Jürgenson Aivar
Published: July 2021

The article examines Baltic German research expeditions to the north-western Caucasus, including Abkhazia, in the late 18th and early 19th centuries, and analyses the results of these trips. Although some of these researchers, such as Peter Simon Pallas and Heinrich Klaproth, came from Germany, most of the researchers were from the Baltic provinces of the Russian tsarist state: Johann Anton Güldenstädt, Otto Moritz Ludwig von Engelhardt, Johann Jacob Friedrich Wilhelm Parrot, and Theodor von Tornau. The main focus of the article is on the descriptions of the north-western region of Abkhazia, where the historical region Dzhigetia or Small Abkhazia is located, and which was inhabited by the Dzhiget ethnic group until the 1860s. Using data from Baltic German authors, especially Theodor von Tornau, an attempt is made to answer the question of whether or not Dzhigetians belonged to the Abkhazians. The article provides an overview of the historical location and fate of Dzhigets in the 19th century. In general, the descriptions of the peoples of the Caucasus provided by the authors of the late 18th and early 19th centuries are superficial and do not follow a uniform classification. Therefore, their interpretation offers different possibilities today. The examples of recent interpretations given in the article convince us that Russian and Abkhaz authors have interpreted earlier authors differently. The most comprehensive accounts of Dzhigetia come from Theodor von Tornau, and it can be argued that the Dzhigetians were an Abkhaz ethnic group. The question of the affiliation of Dzhigets is important in today’s border disputes between Abkhazia and Russia. In the last decade, Russia has made territorial claims to Abkhazia in the region of historic Dzhigetia. It is also declared among the Russian scientific community that Dzhigetia is not historically-ethnically within the borders of Abkhazia. However, Tornau’s data refute these statements of Russian authors. The ethnicity of the peoples of the border areas would probably not solve today’s border problems, but would give to the parties of the dispute symbolic capital and moral support to defend their positions.
Karakteritega suhestumine, netimisogüünia ja representatsioonide materiaalsus
Authors:   Institute of Cultural Research, University of Tartu, Sorokin Siim
Published: July 2021

The present multidisciplinary theoretical article develops its focal line of argument gradually. At first, feminist and narrative theory are consulted; after that, some treatments in the philosophy of mind are discussed. The latter’s correlative relationship with the recent “materialist turn” in philosophy affords to propose a tentative alternative to the current and universally accepted approaches to the (fictional) character much indebted to philosophical idealism. This latter observation also determines the broad – some might argue seemingly overtly complicated – theoretical reach of the article. However, its timely point of departure – the online misogynistic abuse in fan discussions directed at Breaking Bad’s Skyler White and the actress Anna Gunn –, enables to cast the issue of character engagement in necessarily broad terms, disciplinarily speaking. Be it in the context of different scientific disciplines or as the crucial vertebra connecting them, whilst also suggesting far-reaching philosophical implications. This kind of engagement, and especially its expression in online discourse, provides an impetus to inquire about the peculiarities of the human mind and the operation of human thought. Therefore, the present article zooms in on the conventionally understood binary relationship between “fiction” and “reality”, sketching appropriate terminology (continuance, narrative person, realitization) and theoretical framework (inspired, in part, by the Soviet school of philosophical Activity Theory) to help explain the human proclivity to treat characters in naïve realist terms, i.e., as real people. The central research question is as follows: what kind of ramifications can be detected for the conceptualization of character (and narrative) engagement from a particular kind of value-laden reception (like the forms of digital misogyny that emerged in the context of Breaking Bad’s reception)?
An Ayurvedic Approach to Vipadika (Palmoplantar Psoriasis): A Case Study
Authors: Biswas Amrita , Deshpande Amol Madhav , Deshpande Mayuri Amol
Published: July 2021

Ayurveda includes all the skin diseases under the broad name Kushta (Skin Diseases). There are 18 types of skin diseases were described in Ayurved Samhitas. Out of which 11 are Kshudra Kushta. Vipadika (Palmoplantar psoriasis) is one of them. Different Acharyas have given different presentations of signs and symptoms of Vipadika. According to Ashtang hridaya, Panipadsputana (Cracks over palms and soles), Tivra Vedana (severe Pain), Manda Kandu (Mild Itching), and Sarag Pidika (Red-colored Macule) are the symptoms of Vipadika. This skin disease hampers day-to-day activity and depresses patients because of cosmetic issues. This case was about a woman of age 55 years having Itching on the plantar aspect of both feet, cracks over soles, burning sensation, and pain during walking. There was no previous history of any systemic disease. The patient had not undergone any surgical procedure. The patient used to eat pickles twice a day on daily basis. At the first follow-up, the burning sensation was reduced. Then the cracks, itching, and pain during walking reduced with consecutive follow-ups. Raktmokshan (Leech therapy) was planned after every 15 days. Total treatment was about 3 months with a follow-up of 15 days. With this treatment protocol, the patient got completely relieved from all parameters.
Evaluation of Antivenom Activity of Cassia alata Leaf Extract against Daboia Russelii Venom
Authors: Bhat Achala , Rajesh K. S. , Raghavan Reshma
Published: July 2021

Cassia alata, commonly known as candle bush, ringworm bush is an extensively distributed plant of the family Leguminosea. It is an annual and occasionally biannual herb, flowering in the sunshine and humid areas, with an average height of 1 to 4m. Biological activity in plants has been claimed to be effective as antidiabetic, antimicrobial, antioxidant, anti-inflammatory, anti-allergic, antimicrobial, analgesic, anti-ulcer, antiviral, antidepressants, hepatoprotective, antimalarial, anthelmintic, cardiovascular, and anesthetic properties. The ethanolic extract of plant was subjected first time for neutralization of snake venom activity. Primary phytochemical screening shows the existence of alkaloid, steroids, phenols, flavonoids, and triterpenoids. Ethanolic extract of Cassia alata plants was tested for antivenom activity against Daboia russelii venom. Various dose levels of leaf extract 200 and 400mg/kg showed significant neutralization of hemorrhagic activity, and at 400mg/kg leaf extract showed significant necrotizing activity in rats.
A Comprehensive Rehabilitation of a known Case of Leprosy Operated for Midshaft Femur Fracture
Authors: Vaidya Laukik , Bawiskar Dushyant , Upadhyay Prateek , Phansopkar Pratik
Published: July 2021

Background: A persistent infection triggered by Mycobacterium leprae is also known as leprosy or Hansen's disease, transmitting by tiny droplets of the nose and mouth to the skin and peripheral nerves, producing disability. Leprosy therapy is based on the combination of the rifampicin, dispone and clofazimine (MDT) three-drug regimen. In patients who undergo hormone therapy, avascular femoral necrosis (ANFH) or femoral head osteonecrosis (ONFH) may occur, causing steroid-induced femoral head avascular necrosis (SANFH) Core decompression (CD) reduces bone pressure, opens the hardening area, prevents osteonecrosis repair, promotes blood vessel development through the tunnel for decompression, increases bone replacement and delays osteonecrosis.
Patient information, diagnosis and therapeutic interventions: In this case, we found a 20 years old girl known case of leprosy, was on corticosteroids for two and half years. After an increase in dosage of corticosteroids she began difficult for her walk and do her activities of daily living. She visited Acharya Vinoba Bhave Rural Hospital (AVBRH), DMIMS (DU) Sawangi Meghe, Wardha, Maharashtra, India where she got to know about necrosis of head of femur of both lower limbs. She underwent core decompression surgery of bilateral femoral head. For further management she was referred to Physiotherapy Department.
Outcomes and Conclusion:  this case, we found that a patient who is young who had Midshaft femur fracture with interlock nailing and sever kinesiophobia, affecting rehabilitation, was able to resume her ADLs independently.
THE INFLUENCE OF FEMALE DIRECTOR ON THE PROBABILITY OF COMPANIES EXPERIENCING FINANCIAL DISTRESS
Authors: Koerniawan Stephanie Angelina , Malelak Mariana Ing
Published: July 2021

This study aims to determine the effect of Female Director on the Probability of a Company Experiencing Financial Distress. Springate model is used to predict the probability of a company experiencing financial distress. This study compares the effect of female director on the probability of a company experiencing financial distress without control variables and using control variables. The control variables in this study are board size, firm size and leverage. The population in this study were manufacturing companies listed on the Indonesia Stock Exchange in the period 2013-2018. The samples in this study were 27 companies. The results of this study indicate that female directors have no significant effect on the probability of a company experiencing financial distress. By using control variables, it is shown that female directors do not significantly influence the probability of a company experiencing financial distress with the control variables such as board size, firm size, and leverage.
THE EFFECT OF SALIENCE AND DISPOSITION EFFECT ON STOCK INVESTMENT DECISIONS ON INVESTORS IN SURABAYA
Authors: Subandi Jessica Ratna , Basana Sautma Ronni
Published: July 2021

This study aims to prove the effect of salience and disposition on investors' investment decisions in Surabaya. In addition, this study also seeks to see the effect of salience and disposition effect on investment decisions with the type of investor as a moderating variable. This type of research is quantitative research with associative methods and primary data sources. The data collection technique used a questionnaire. The data that has been collected is then processed using Partial Least Squares (PLS). The results showed that the salience and disposition effect had a significant influence on investment decisions. In addition, the types of investors weaken the relationship between the salience and disposition effect on investment decisions.
THE INFLUENCE OF EMOTIONAL FACTORS, MATERIALISM, RISK PERCEPTION, AND FINANCIAL LITERACY ON THE TENDENCY OF DEBT OF MILLENNIAL GENERATION IN SURABAYA
Authors: Widjaja Richard , Pertiwi Dewi
Published: July 2021

This study aims to determine the effect of emotion, materialism, risk perception, and financial literacy on the propensity toward indebtedness of the millennial generation in Surabaya. The researcher uses a online questionnaire distributed via Google Form to 110 millennials in Surabaya. The collected data is processed using Partial Least Square (PLS). This study indicates that emotion, materialism, and perceptions have a significant effect on indebtedness propensity.
VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer
Authors: Ghate Nikhil Baban , Kim Sangnam , Spiller Erin , Kim Sungmin , Shin Yonghwan , Rhie Suhn K. , Smbatyan Goar , Lenz Heinz‐Josef , Mumenthaler Shannon M. , An Woojin
Published: July 2021

Histone modification is aberrantly regulated in cancer and generates an unbalanced state of gene transcription. VprBP, a recently identified kinase, phosphorylates histone H2A on threonine 120 (T120) and is involved in oncogenic transcriptional dysregulation; however, its specific role in colon cancer is undefined. Here, we show that VprBP is overexpressed in colon cancer and directly contributes to epigenetic gene silencing and cancer pathogenesis. Mechanistically, the observed function of VprBP is mediated through H2AT120 phosphorylation (H2AT120p)‐driven transcriptional repression of growth regulatory genes, resulting in a significantly higher proliferative capacity of colon cancer cells. Our preclinical studies using organoid and xenograft models demonstrate that treatment with the VprBP inhibitor B32B3 impairs colonic tumor growth by blocking H2AT120p and reactivating a transcriptional program resembling that of normal cells. Collectively, our work describes VprBP as a master kinase contributing to the development and progression of colon cancer, making it a new molecular target for novel therapeutic strategies.
Novel dominant distal titinopathy phenotype associated with copy number variation
Authors: Perrin Aurélien , Juntas Morales Raul , Chapon Françoise , Thèze Corinne , Lacourt Delphine , Pégeot Henri , Uro‐Coste Emmanuelle , Giovannini Diane , Leboucq Nicolas , Mallaret Martial , Lagrange Emmeline , Rigau Valérie , Gaudon Karen , Richard Pascale , Koenig Michel , Métay Corinne , Cossée Mireille
Published: July 2021

The aim of this study was to analyze patients from two distinct families with a novel distal titinopathy phenotype associated with exactly the same CNV in the TTN gene. We used an integrated strategy combining deep phenotyping and complete molecular analyses in patients. The CNV is the most proximal out‐of‐frame TTN variant reported and leads to aberrant splicing transcripts leading to a frameshift. In this case, the dominant effect would be due to dominant‐negative and/or haploinsufficiency. Few CNV in TTN have been reported to date. Our data represent a novel phenotype–genotype association and provides hypotheses for its dominant effects.
Complex Growth Behavior of Li Dendrites in Al2O3 Nanoparticles‐Driven Viscoelastic Electrolytes for Lithium Metal Batteries: Dynamic versus Quasistatic Rheology
Authors: Park Kyobin , Lee Myungjae , Kim Dong‐Min , Kwon Bomee , Lee Jeonghyeop , Jo Seunghyeon , Nam Jaewook , Lee Kyu Tae
Published: July 2021

Viscoelastic electrolytes have been focused as innovative electrolytes for Li metal batteries because of their unique mechanical and electrochemical properties compared to conventional Newtonian liquid electrolytes. However, the role of the mechanochemical properties of viscoelastic electrolytes in the electrochemical performance of Li metal has not been fully understood yet. In particular, dynamic rheology of viscoelastic electrolytes has not been considered one of significant factors accelerating Li dendrites growth. Herein, Al2O3 nanoparticles‐driven viscoelastic electrolytes are introduced to improve the electrochemical performance of Li metal. In contrast to conventional Newtonian liquid electrolytes, viscoelastic electrolytes significantly suppress Li dendrites growth during cycling, resulting in excellent electrochemical performance, such as stable capacity retention over 400 cycles. Moreover, the complex growth mechanism of Li dendrites in viscoelastic electrolytes is demonstrated in terms of dynamic versus quasistatic rheology. Dynamic rheology prevails over quasistatic rheology as Al2O3 weight fraction and current density is increased in viscoelastic electrolytes. Dynamic rheology gives rise to spatial non‐uniformity in the mechanical and rheological properties of viscoelastic electrolytes, leading to promoting Li dendrites growth due to the uneven distribution of local current density on the Li metal surface. These findings provide fundamental insights into strategies to design advanced electrolytes for Li metal batteries.
Copper‐Catalyzed Chemo‐ and Diastereoselective 1,3‐Dipolar Cycloaddition of Carbonyl Ylide and Aldehyde‐Tethered‐Cyclohexadienone to Access Polycyclic Systems
Authors: Peng Shiyong , Zhang Hong , Zhu Yuqi , Zhou Ting , He Jieyin , Chen Nuan , Lang Ming , Li Hongguang , Wang Jian
Published: July 2021

A copper‐catalyzed tandem intermolecular ylide formation/intramolecular cycloaddition of diazo compounds and aldehyde‐tethered‐cyclohexadienones was reported, chemo‐ and diastereoselectively providing oxapolycyclic frameworks in moderate to excellent yields under mild conditions. This reaction creates two C−C bonds and one C−O bond with five stereocentres including two all‐carbon quaternary centres. Moreover, the late‐stage diversification of products can be realized via chemoselective substitutions.

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Multicomponent Catalytic Enantioselective Synthesis of Isoxazolidin‐5‐Ones
Authors: Annibaletto Julien , Martzel Thomas , Levacher Vincent , Oudeyer Sylvain , Brière Jean‐François
Published: July 2021

We report herein a strategy to afford a multicomponent catalytic enantioselective synthesis of β‐substituted isoxazolidin‐5‐ones via a KMC process promoted by a suited cupreine used as bifunctional organocatalyst. The hydroxamic acid component, with a sterically hindered amide moiety, proved to be key for the successful formation and transformation of the obtained original N‐amide isoxazolidin‐5‐ones.

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Mentoring Children in Foster Care: Examining Relationship Histories as Moderators of Intervention Impact on Children’s Mental Health and Trauma Symptoms
Authors: Weiler Lindsey M. , Lee Sun‐Kyung , Zhang Jingchen , Ausherbauer Kadie , Schwartz Sarah E. O. , Kanchewa Stella S. , Taussig Heather N.
Published: July 2021

Mentoring‐based interventions show promise among children in foster care, but previous research suggests that some benefit more than others. Because children in foster care experience relationship disruptions that could affect mentoring effectiveness, we examined whether children’s relational histories at baseline (i.e., relationship quality with birth parents, relationship quality with foster parents, caregiver instability, and previous mentoring experience) moderated the impact of a mentoring intervention on children’s mental health, trauma symptoms, and quality of life. Participants included 426 racially and ethnically diverse children (age: 9–11; 52% male) who participated in a randomized controlled trial of the Fostering Healthy Futures program (FHF), a 9‐month one‐to‐one mentoring and skills group intervention. Results showed that relationship quality with foster parents and prior mentoring experience did not moderate intervention impact. Relationship quality with birth parents and caregiver instability pre‐program, however, moderated the effect on some outcomes. The impact on quality of life was stronger for children with weaker birth parent relationships and fewer caregiver changes. Likewise, the impact on trauma symptoms was stronger for those with fewer caregiver changes. Overall, FHF seems to positively impact children with varied relational histories, yet some may derive more benefits – particularly those with fewer caregiver changes pre‐program.
Mortality in the Western Pyrenees during the 18th century. Data from the parish register of the village of Arudy (1741–1800), Bearn, France
Authors: Dugène Jean‐Pierre , Bauduer Frédéric
Published: July 2021

Objectives

We aimed to determine the public health status of an 18th century mountain locality.

Methods

We collected data registered in parish death certificates from Arudy, a small village in the French Pyrenees during the period 1741–1800.

Results

Two thousand and six hundred and sixty‐three cases were studied. About 50% of deaths occurred during the first 10 years of life. There were some particularities in deaths pattern with regards to age categories between males and females and seasonality. A fraction of individuals died at advanced ages (24.1% ≥60 years and of note three cases ≥100 years). The cause of death was reported in only 2.2% of cases (nearly always sudden fatalities). Maternal mortality could not be precisely determined. Throughout this period we identified a series of mortality crises which targeted mostly children and were probably in relation with undocumented epidemics.

Conclusions

These data offer some clues about the sanitary situation of an European mountain community during the 18th century.
Cobalt‐Catalysed, Ligand‐Controlled Regiodivergent Alkene Hydrosilylation
Authors: Docherty Jamie H. , Dominey Andrew P. , Thomas Stephen P.
Published: July 2021

Alkene hydrosilylation is amongst the largest industrial homogenous catalysis processes. Cobalt catalysis offers a sustainable alternative to commonly used platinum catalysts to achieve this transformation. Using two bisiminopyridine cobalt(II) catalysts the regiodivergent hydrosilylation of alkenes has been developed. Variation of pre‐catalyst activator and ligand substituents were investigated to enable the controlled, regiodivergent hydrosilylation of both aryl‐ and alkyl‐substituted alkenes with phenylsilane. In contrast to other regiodivergence strategies, excellent regioselectivity for either isomer was achieved using the same ligand class but differing by a single methyl group (ethylvs isopropyl).
Designable Assembly of Aluminum Molecular Rings for Sequential Confinement of Iodine Molecules
Authors: Liu Chen‐Hui , Fang Wei‐Hui , Sun Yayong , Yao Shuyang , Wang San‐Tai , Lu Dongfei , Zhang Jian
Published: July 2021

Although numerous adsorbent materials have been reported for the capture of radioactive iodine, there is still demand for new absorbents that are economically viable and can be prepared by reliable synthetic protocols. Herein, we report a coordination‐driven self‐assembly strategy towards adsorbents for the sequential confinement of iodine molecules. These adsorbents are versatile heterometallic frameworks constructed from aluminum molecular rings of varying size, flexible copper ions, and conjugated carboxylate ligands. Additionally, these materials can quickly remove iodine from cyclohexane solutions with a high removal rate (98.8 %) and considerable loading capacity (555.06 mg g−1). These heterometallic frameworks provided distinct pore sizes and binding sites for iodine molecules, and the sequential confinement of iodine molecules was supported by crystallographic data. This work not only sets up a bridge between molecular rings and infinite porous networks but also reveals molecular details for the underlying host–guest binding interactions at crystallographic resolution.
Asymmetric Enamide–Imine Tautomerism in the Kinetic Resolution of Tertiary Alcohols
Authors: Tang Mengyao , Gu Huanchao , He Shunlong , Rajkumar Subramani , Yang Xiaoyu
Published: July 2021

An efficient protocol for kinetic resolution of tertiary alcohols has been developed through an unprecedented asymmetric enamide‐imine tautomerism process enabled by chiral phosphoric acid catalysis. A broad range of racemic 2‐arylsulfonamido tertiary allyl alcohols could be kinetically resolved with excellent kinetic resolution performances (with s‐factor up to >200). This method is particularly effective for a series of 1,1‐dialkyl substituted allyl alcohols, which produced chiral tertiary alcohols that would be difficult to access via other asymmetric methods. Facile and versatile transformations of the chiral α‐hydroxy imine and enamide products, especially the efficient stereodivergent synthesis of all four stereoisomers of β‐amino tertiary alcohols using one enantiomer of the catalyst, demonstrated the value of this kinetic resolution method.
Aggregation‐Induced Emissive Carbon Dots Gels for Octopus‐Inspired Shape/Color Synergistically Adjustable Actuators
Authors: Wu Shuangshuang , Shi Huihui , Lu Wei , Wei Shuxin , Shang Hui , Liu Hao , Si Muqing , Le Xiaoxia , Yin Guangqiang , Theato Patrick , Chen Tao
Published: July 2021

Some living organisms such as the octopus have fantastic abilities to simultaneously swim away and alter body color/morphology for disguise and self‐protection, especially when there is a threat perception. However, it is still quite challenging to construct artificial soft actuators with octopus‐like synergistic shape/color change and directional locomotion behaviors, but such systems could enhance the functions of soft robotics dramatically. Herein, we proposed to utilize unique hydrophobic carbon dots (CDs) with rotatable surficial groups to construct the aggregation‐induced emission (AIE) active glycol CDs polymer gel, which could be further employed to be interfacially bonded to an elastomer to produce anisotropic bilayer soft actuator. When putting the actuator on a water surface, glycol spontaneously diffused out from the gel layer to allow water intake, resulting in a color change from a blue dispersion fluorescence to red AIE and a shape deformation, as well as a large surface tension gradient that can promote its autonomous locomotion. Based on these findings, artificial soft swimming robots with octopus‐like synergistic shape/color change and directional swimming motion were demonstrated. This study provides an elegant strategy to develop advanced multi‐functional bio‐inspired intelligent soft robotics.
Schottky Barrier‐Induced Surface Electric Field Boosts Universal Reduction of NOx− in Water to Ammonia
Authors: Gao Peng , Xue Zhong‐Hua , Zhang Shi‐Nan , Xu Dong , Zhai Guang‐Yao , Li Qi‐Yuan , Chen Jie‐Sheng , Li Xin‐Hao
Published: July 2021

NOx− reduction acts a pivotal part in sustaining globally balanced nitrogen cycle and restoring ecological environment, ammonia (NH3) is an excellent energy carrier and the most valuable product among all the products of NOx− reduction reaction, the selectivity of which is far from satisfaction due to the intrinsic complexity of multiple‐electron NOx−‐to‐NH3 process. Here, we utilize the Schottky barrier‐induced surface electric field, by the construction of high density of electron‐deficient Ni nanoparticles inside nitrogen‐rich carbons, to facilitate the enrichment and fixation of all NOx− anions on the electrode surface, including NO3− and NO2−, and thus ensure the final selectivity to NH3. Both theoretical and experimental results demonstrate that NOx− anions were continuously captured by the electrode with largely enhanced surface electric field, providing excellent Faradaic efficiency of 99 % from both electrocatalytic NO3− and NO2− reduction. Remarkably, the NH3 yield rate could reach the maximum of 25.1 mg h−1 cm−2 in electrocatalytic NO2− reduction reaction, outperforming the maximum in the literature by a factor of 6.3 in neutral solution. With the universality of our electrocatalyst, all sorts of available electrolytes containing NOx− pollutants, including seawater or wastewater, could be directly used for ammonia production in potential through sustainable electrochemical technology.
Laparoscopic‐Assisted Ventriculoperitoneal Shunt Placement: A Less Invasive Approach to Treating Hydrocephalus
Authors: Karasin Beth , Eskuchen Lauren , Hardinge Tara , Watkinson Johanna , Grzelak Monica , Boyce Marissa
Published: July 2021

Hydrocephalus is caused by the disruption of the normal flow of cerebrospinal fluid (CSF), which results in a buildup of CSF. Hydrocephalus comprises two key categories: communicating and noncommunicating. Normal‐pressure hydrocephalus, a type of communicating hydrocephalus, currently has no cure; the main treatment option is ventriculoperitoneal shunt (VPS) placement surgery. This procedure is performed to reestablish the balance between CSF production, flow, and absorption. Recently, general surgeons have begun assisting the neurosurgeon by placing the distal or abdominal end of the shunt using a laparoscopic technique. This article briefly reviews the pathophysiology and treatment options for hydrocephalus; presents a thorough review of the laparoscopic‐assisted VPS placement procedure, as well as the expected perioperative course and care considerations; and concludes with a case study of a 68‐year‐old patient who undergoes a laparoscopic‐assisted VPS placement.