bluuebunny/crossref_metadata_2025 huggingface dataset:
FACTORS ASSOCIATED WITH HIGH RISK FOR CARCIROGENIC HPV INFECTION
Authors: Volchenko A. N. , Belyakovsky V. N.
Published: September 2022

The article presents the results of analytical case-control study of the identifying factors associated with high carcinogenic risk for HPV infection in general women`s population and in group under 30. The study reveals a correlation between the high risk for the HPV-infection and chronic inflammation (OR 18,1; 95 % CI 2,4-133,8), pathological transformation zone of cervical epithelium (OR 5,0; 95 % CI 1,2-21,6), urogenital infection (OR 2,2; 95 % CI 1,6-3,1), sexual conduct (OR 3,0; 95 % CI 1,8-4,9), smoking (OR 1,7; CI 1,1-2,6), drinking (OR 1,5; CI 1,0-2,1). On the contrary, married status (OR 0.7; 0,5 % CI 0,5-0,97) and stable sexual partner (OR 0,3, 95 % CI 0,2-0,6) were factors associated with low prevalence of HPV infection.
TRANSPOSITIONS OF MUSCLES IN INJURIES OF BRACHIAL PLEXUS
Authors: Divovich G. V. , Makarchyk A. V. , Titenkov V. M.
Published: September 2022

The literary data on the application of orthopedic operations in irreversible brachial plexities, i.e. transpositions of muscles of the neck, trunk and upper extremities on denervated muscles of the shoulder joint, have been analyzed. According to the revision of views on the mechanism of movements in the shoulder joint the traditionally developed methods of performance of such operations and latest working-outs in the methods of surgical interventions were considered. Based on the analysis were outlined the ways of new investigations in the surgery of tendomiotranspositions in affections of brachial plexities.
MORPHOLOGIC CHARACTERISTICS OF ATHEROSCLEROSIS OF THE AORTA INTESTINAL SEGMENT IN YOUNG POPULATION OF GOMEL REGION
Authors: Linkevich E. E.
Published: September 2022

According to WHO program, the visual-planimetric study of aorta intestinal segment samples in young population (age interval 20-49) of Gomel region has been carried out for epidemiologic research of atherosclerosis. 84 (94,4 %) of the 89 studied samples detected atherosclerotic process at various stages. Complicated lesions indicating an unstable pathological process were already registered at the age of 25-29. There was an intensive decrease of FP/CL (fibrous plaques and complicated lesions) index with age which expresses an area ratio of fibrous plaques and high lesions and is an integral index of atherosclerosis progressing rate. The received data are evident of «rejuvenation» and quick progressing of atherosclerosis in the young population of Gomel region which in turn can be a consequence of unfavorable exo- and endogenic effect on the vascular wall.
SOMATOTYPICAL FEATURES OF MORPHOMETRIC CHARACTERISTICS OF EXTRAORGANIC BILIARY DUCTS IN ADULTS
Authors: Samokhina A. V. , Pivchenko P. G.
Published: September 2022

Aim of research: to establish correlative dependence patterns of morphometric characteristics of extrahepatic biliary ducts on a human somatotype. Material and methods: 104 liver samples with gall - bladder and biliary ducts were examined by means of morphometric and statistical methods. Results of study: the length of extrahepatic biliary ducts prevailed in subjects with dolichomorphic somatotype, and the widthin subjects of brachymorphic somatotype. The morphometric and morphologic characteristics of extrahepatic biliary ducts in mezomorphic somatotype acquire intermediate values. Conclusion: statistically relevant differences have been revealed in people with different constitutional types regarding an angle of convergence values, the length and width of hepatic ducts, common hepatic and common biliary ducts as well as cystic and pancreatic ducts.
FEATURES OF DIGITAL AND PALMAR DERMATOGLYPHICS OF MEN WITH ONCOLOGIC THYROID PATHOLOGY
Authors: Shesterina E. K. , Melnov S. B.
Published: September 2022

To reveal specific phenotypic markers and develop criteria for prenosological diagnostics for oncologic pathology of thyroid gland, the peculiarities of the dermatoglyphic parameters of patients with this pathology have been assessed.
SATISFACTION OF POPULATION WITH OUT-PATIENT MEDICAL CARE (based on the materials of a public opinion poll)
Authors: Budnik Ya. I. , Sharshakova T. M.
Published: September 2022

Mmendations for its improvement. Materials and methods: 220 patients who had appealed to clinics and therapeutic departments of Gomel hospitals were involved into the questionnaire poll. Of them, the most were women (51,4 %), and 48,6 % were men. 86,4 % made up urban citizens and 13,6 % were rural. The data were collected by means of questionnaires, conducted by a house-to-house poll. Results: According to the data of the conducted public opinion poll, 48 % of the respondents appealed to the polyclinics with acute illness and only 23 % with chronic ones. It should be noted that only 14 % respondents attended the polyclinic for prophylactic medical examination and only 6 % for mass health examination. Nearly half of respondents (46,8 %) said that they preferred to dispense with medical aid and with the first symptoms of the illness were engaged in self-treatment, 13,6 % called an ambulance team and only 37,7 % appealed to the polyclinic. 42,7 % of the respondents were under dispensary medical observation. The respondents mentioned the following main causes of dissatisfaction with medical care as «lack of desired results» (54,1 %), «inconvenient schedule of specialists (16,4 %), «inadequate qualification level of specialists» (10,5 %), «improper treatment of specialists» (12,3 %) and 6,8 % mentioned other causes. 29,1 % of the respondents positively assessed the changes in the organization of medical care over the past 2-3 years, 10 % believed that the situation had worsened, 60,9 % noted that it had not changed, and only 21,8 % of the respondents regarded that the examination in the polyclinic corresponded to the up-to-date level, 22,3 % believed that it did not meet the requirements and 46,8 % noted that it fell short of the adequate extent. 67,3 % of the respondents reported that along with prescription of medical drugs they had received from the attending physician also the guidelines for the disease prevention and correction of risk factors, and only 58,2 % of the respondents were informed by the physician about their risk factors for disease development. Conclusion: The carried out survey showed that the patients who appealed for medical aid to the polyclinic had a number of remarks on the quality of their treatment. The negative moments they described were as follows: queues, poor access to the care of narrow specialists, inattentive attitude of the physicians, cases of maltreatment from the staff of polyclinics, lack of necessary specialists. This led to the fact that sometimes, when patients developed a disease or their condition became aggravated they preferred not to appeal to the polyclinic. According to the poll results one can conclude that health care providers prefer to give treatment but not to prevent an illness. This should be considered when guiding health care organizations to achieve the «consumer» satisfaction with health services.
OPTIMIZATION OF TRAINING AT THE FACULTY OF DIAGNOSTIC MEDICINE IN THE CONTEXT OF THE CODE ON EDUCATION OF THE REPUBLIC OF BELARUS
Authors: Lyzikov A. N. , Kalinin A. L. , Kozlovsky A. A. , Butenkova E. M.
Published: September 2022

Objective: to study the facilities of higher, further and postgraduate training in the specialty «Diagnostic Medicine» at Gomel State Medical University. Material and methods. The professional competencies were analyzed in accordance with the standard on stage I of higher education in the specialty of Diagnostic Medicine OS RB 79 01 04 - 2007 and were compared with those as a result of training at Magistrature, Clinical Residency and retraining of the graduates of the Faculty of Diagnostic medicine (DMF) in accordance with the Common Сlassifier of the Republic of Belarus (ССRB). The educational opportunities and ways to improve the training were evaluated in connection with the introduction of the Code on Education of the Republic of Belarus. Results. The Standard clearly formulates the potential of higher medical training in four specialties of diagnostic specialization: clinical laboratory diagnostics, performance of laboratory research at the departments of laboratory service in centers for hygiene and epidemiology, radiation and functional diagnostics and asserts the list of medical knowledge and skills of a physician in these areas. DMF graduates can continue their training at the departments with a high demand for scientifically-pedagogical workers in the following magistrature specialties: «Human anatomy», «Pathophysiology, Physiology», «Biochemistry», «Microbiology, virology», «Histology, cytology, cell biology», «Public health and health care». The clinical residency makes it possible to receive additional education in all the specialties in accordance with the Standard. The Faculty trains highly qualified scientific personnel, the graduates having specialized in Diagnostic Medicine get training in the field of seven postgraduate specialties available at the University: «Biochemistry», «Physiology», «Pathophysiology», «Anatomy», «Public health and health care», «Clinical Laboratory Diagnostics», «Parasitology». Conclusion. The training at the Faculty as a whole corresponds to the principle of lifelong educational opportunities in accordance with the Code on Education of the Republic of Belarus. There are not such clinical specialties at the Magistrature as Radiation Diagnostics. Certain areas of training should obtain more potential for taking an internship in Diagnostic Medicine: functional diagnostics, ultrasound diagnosis, pathological anatomy. The best graduates will be able to continue their training at postgraduate school in the fundamental medical subjects, as well as in one clinical specialty, i.e. clinical laboratory diagnostics.
ИССЛЕДОВАНИЕ ТОКСИЧЕСКОГО ВОЗДЕЙСТВИЯ ШОВНОГО МАТЕРИАЛА, МОДИФИЦИРОВАННОГО НАНОЧАСТИЦАМИ СЕРЕБРА
Authors: Kabeshev B. O. , Bontsevich D. N. , Vasilkov A. Yu.
Published: September 2022

The aim of research: to obtain new suture material modified by silver nanoparticles, which has an antibacterial effect, and to study the hemolytic effect on human erythrocytes and toxic effect on the germ cells of cattle. Material and methods. Nylon modified by silver nanoparticles has been used in the research. The methods to determine the hemolytic effect of polymeric materials in vitro and the toxic effects of extracts on bull’s sperm cells were used. The method to determine the hemolytic effect of polymeric materials was reproduced on the extracts obtained on the third and tenth days of the exposure. The results. The hemolysis percentage in all the samples made up less than 2, which made it possible to draw a conclusion about the absence of hemolytic effect of the extracts. The investigation of the effect of the extracts on the bull’s sperm cells revealed a significant increase in the time of sperm motility in the third- and tenth-day exposure samples compared with the control ones: 55, 45 and 32.5 minutes, respectively. Conclusion. The extracts from the suture material modified by silver nanoparticles do not possess a hemolytic effect and do not exert a toxic impact on the germ cells of cattle.
PECULIARITIES OF VERTEBRAE VASCULARISATION: ANATOMIC BASIS FOR RADIOLOGISTS (literature review)
Authors: Mikhailov A. N. , Yurkovskiy A. M. , Gonchar A. A. , Filyustin A. E.
Published: September 2022

Aim of research: To analyze and systematize the data on clinical and radiological anatomy of spinal vascular structures. Materials and methods: articles about peculiar features of vertebrae vascularization on English PubMed site and some Russian-language medical publications from 1973 to 2011. Results. The most important features of vertebrae blood supply have been singled out from clinical point of view. Conclusion. Only a good knowledge of vertebrae vascularisation features makes it possible to give an adequate interpretation to the radiological diagnostics of backbone arterial inflow and venous outflow and timely diagnose their disfunction.
APPLICATION OF PSYCHOTHERAPY IN COMPLEX TREATMENT FOR SEVERE HERPETIC INFECTION (literature review)
Authors: Shilova N. P.
Published: September 2022

The article describes approaches to the diagnosis and treatment for chronic dermatosis, including recurrent herpetic infection, based on studying of the psychological characteristics of patients. The attention is focused on the application of psychotherapeutic methods in the combination with traditional management methods.
PNEUMONIA IN PATIENTS WITH LIVER CIRRHOSIS DECEASED IN HOSPITAL
Authors: Gavrilenko D. I.
Published: September 2022

The results of the data on 308 cirrhotic patients, deceased in hospital have been analyzed. This research was aimed at the determination of incidence rate and some clinical and epidemiological features of pneumonia in this category of patients. Pneumonia was established to cause complications after cirrhosis in 97 (31,49 % 95 % CI 26,32-36,66) patients deceased in hospital and was the most prevalent infectious concomitant complication in these patients. At the same time, the patients with pneumonia detected sepsis and other infections oftener that the patients without pneumonia. Fatal outcomes occurred in the cirrhotic patients with pneumonia in a shorter period after hospitalization than in the patients without pneumonia. Twenty-four patients were not diagnosed with pneumonia during their lifetime at all. They observed nosocomial forms of the disease. The causative agents of pneumonia in the deceased with liver cirrhosis were microorganisms, which caused illnesses in the hospitalized and immunodeficient patients.
PSYCHOLOGICAL RELAPSE-DANGEROUS CLINICAL CONDITIONS IN ALCOHOL ADDICTS IN EARLY THERAPEUTIC REMISSION
Authors: Skvira I. M.
Published: September 2022

The article presents the data on the incidence of psychological relapse-dangerous clinical conditions in alcohol depended patients within the first 6 months of the therapeutic remission period (F10.200-202). The recommendations have been formulated on early diagnosis and therapy of the patients with alcoholic dependence during their treatment and rehabilitation.
PREVALENCE OF HUMAN PAPPILOVIRUSES IN UPPER RESPIRATORY TRACTS OF HALF-YEAR-OLD INFANTS BORN FROM INFECTED WOMEN
Authors: Kravchenko S. S. , Vergeychik G. I.
Published: September 2022

With high HPV-infection prevalence among reproductive women there is an increased HPV incidence rate in pregnant women. Cases of papillomatosis of larynx, trachea, bronchi in children, born from infected mothers, testify to the possibility of not only intranatal, transplacental ways, but also of contact transmission of the infection from mother to child. Therefore, at present the definition of frequency and risk factors for HPV persistence in the upper respiratory tracts of the children born from women with both clinical and subclinical evidence of the infection is quite topical.
LUMBAR OSTEOСHONDROSIS: DIAGNOSIS, TRЕАTMENT, MEDICAL REHABILITATION
Authors: Sviatskaya E. F.
Published: September 2022

The article presents the basic issues of diagnosis, treatment and medical rehabilitation of patients with neurological manifestations of lumbar osteochondrosis. The risk factors, pathogenesis of neurological syndromes, clinical and instrumental diagnosis methods of arising disturbances have been singled out. The approaches to the treatment have been given at different stages of the illness. The methods of medical rehabilitation of this cohort of the patients have been stated in detail. A particular attention is paid to physical methods of rehabilitation, being fundamental in the restoration of neurological deficiency.
DEPENDENCE OF VEGETATIVE STATUS ON SEVERITY OF CEREBRAL ISCHEMIC LESION
Authors: Galinovskaya N. V. , Smychek V. B. , Latysheva V. Ya. , Usova N. N. , Bazhkova N. V.
Published: September 2022

To analyse vegetative status in cerebral ischemic lesions, 439 patients aged from 48 to 74 have been examined. As a result it has been shown that vagotonia with normal reactivity is prevalent in persons with brain infarction irrespective of severity of neurological deficiency, and sympathicotomy, being the most evident in case there are no focal symptoms of cerebral tissue lesions, is characteristic for the passing forms.
A CLINICAL CASE OF CORDARONE-INDUCED THYROTOXICOSIS IN A PATIENT WITH PAROXYSM OF CILIARY ARYTHMIA
Authors: Krivelevich N. B. , Shilova V. A. , Naumenko E. P. , Fedorenko O. V.
Published: September 2022

Objective. To discuss the clinical study of the development of cordarone-associated thyrotoxicosis. Results and discussion. The female patient D., born in 1956, had been under observation since 2007 on ciliary arythmia and artery hypertension. Sinus rhythm (SR) was restored and maintained by the application of cordarone. In March 2010 due to recrudescence the patient was hospitalized into the Department of Immunopathology and Allergology, Republican Research Center for Radiation Medicine and Human Ecology. After the clinical examination she was diagnosed with «cordarone-induced» thyrotoxicosis, probably, of type 2. It was recommended to stop using cordarone. Thyrotoxicosis was managed with methylprednisolone, and antiarythmic therapy was conducted with sotalex, propranolol, propafenone, strofantine (with no effect), also electropulse therapy was provided (rhythm was restored). To administer supporting antiarythmic therapy, it was recommended to take alapenin and bisoprolol. In the sequel, the patient revealed euthyroidism, the level of thyroidal hormones was at a norm. However, later there were frequent paroxysms of atrium fibrillation, short-term paroxysm of ventricular tachycardia. The patient was sent to have a consultation at the Laboratory for Heart Rhythm Disturbances of the Republican Research Center «Cardiology». Conclusion. Thus, the above-mentioned clinical observation makes it possible to draw a conclusion that long-term intake of cordarone can change metabolism of thyroidal hormones and, possibly, the electrophysiological properties of heart.
OZONE THERAPY IN REHABILITATION TREATMENT OF PATIENTS WITH ISCHEMIC DISEASE
Authors: Kovalchuk P. N. , Kovalchuk L. S.
Published: September 2022

The clinical efficacy of rehabilitation treatment under the impact of ozone therapy has been studied in patients with ischemic heart disease. 155 patients with exertional angina of I and II functional classes were examined in a health resort. Of them, 105 patients underwent ozone therapy on the ozonator made by firm «Medozone» (Moscow) with ozone concentration 2,5-3 mg/l. The results of the research testify to the high clinical efficacy of the method at the expense of the activation of oxygen supply mechanism and rising of the functional reserves of cardiovascular system. The method of parenteral introduction of ozone oxygen mixture extends opportunities of the management of stenocardia patients with high risk for complication development and availability of concomitant diseases.
GOODPASTURE'S SYNDROME (сase from clinical practice)
Authors: Shaliga I. F. , Martemianova L. A. , Kanaplianik O. V.
Published: September 2022

Presented a case of rare pathology Goodpasture's syndrome in a younger patient with a clinical diagnosis polysegmentary bronchopneumonia, chronic glomerulonephritis, chronic sepsis, after clinical and morphological analysis of the case exposed the diagnosis of hemorrhagic pneumo-renal syndrome. Discussed the morphological changes in organs and their relationship to clinical and laboratory and instrumental methods. Show in a concrete example low verification of lifetime diagnostic of this disease.
THE ADVANTAGES OF BODY CONTOUR SURGERY USING COMPUTER MODELLING
Authors: Kurek M. F.
Published: September 2022

Objective: to develop a method of objective planning for body contour surgery by means of computer modelling. Materials and methods: 108 patients who have undergone 116 operations, of them, 60 using computer modelling, 56 - formed the control group. Results and conclusions: the planning of body contouring procedures using computer modelling makes it possible to improve the postoperative results and lower the frequency rate of reoperations. Conclusion: the developed method can be recommended for wide practical application.
THE ROLE OF PHARMACOGENETICS IN THE DEVELOPMENT OF PERSONALIZED MEDICINE FOR DISEASES OF INTERNAL ORGANS (literature review)
Authors: Volovikova O. N. , Mikhailova E. I.
Published: September 2022

Research objective: to study the role of metabolism fermental systems in biotransformation of various medicines, to define the value of pharmagenetics in the development of personalized medicine. Material of research: the publications containing information about functioning of metabolism fermental systems, medicines participating in the biotrasformation of medical preparations. Conclusion. The role of CYP450 enzyme in the biotransformation of various medicines was studied. The value of pharmagenetics was considered to optimize and individualize the medicine prescription mode to achieve their maximum therapeutic and safest effect.
OSTEOANTHROPOLOGICAL STUDY OF BONE REMAINS
Authors: Doroshenko R. V. , Nadyrov E. A. , Makushnikov O. A. , Raduik V. V.
Published: September 2022

This article presents the results of medical and anthropological study of the bone remains found in the three burial mounds of Mokhov, provided by the Department of Eastern Slavs History of Gomel State University named after F. Skorina. The aim of this work was to compare the data on the fossils obtained by archaeological and medical and anthropological methods, and to assess the accuracy of the information received by each of the methods. The comparison of the research results showed that the medical anthropological study by single parameter gave more accurate results.
THE FEATURES OF ELEMENTAL HAIR STRUCTURE IN CHILDREN AND ADOLESCENTS WITH REFLUX-ESOPHAGITIS
Authors: Zagorskiy S. E. , Melnov S. B.
Published: September 2022

The article covers the results of the research of elemental hair structure in 112 children and adolescents with reflux-esophagitis aged from 12 to 18. Among essential bioelements, low level of selenium and high level of chronium were determined in 60,7 and 76,4 % cases, respectively. High concentration of such toxic metals as lead and cadmium was registered in 26,6 and 11,5 % patients respectively; level of mercury and bismuth was normal. The girls had high levels of calcium, potassium and copper oftener than the boys. The frequency rate of abnormal high lead level increased with age: from 12,5 % children at age of 12-14 to 32,5 % in adolescents at age of 15-18 (р = 0,035).
CYCLOPHOSPHAN - INDUCED DEVELOPMENT OF MANDIBLE
Authors: Kitel V. V.
Published: September 2022

We have studied the mechanisms of developing mandible anomalies induced by cyclophosphan. The material of the research was 18- and 20-days’ fetuses of outbred white rats given cyclophosphan in the dosage of 20 mg/kg on the twelfth day of embryogenesis. While studying the clarified specimens and series of histological sections it was revealed that a single introduction of cyclophosphan into pregnant rats caused hypoplasia of body and mandible ramus. The reparative regeneration, which became apparent in the enhancement of chondro- and osteogenesis, did not provide complete structural restoration of the bone as an organ. The formed appendices were not fully developed, which resulted later in the retardation of temporomandibular joint formation and impairment of the balanced development of teeth-gum system.
THE SKIN REGENERATION FEATURES IN APPLICATION OF MULTIPOTENT MESENCHYMAL STEM CELLS FROM ADIPOSE TISSUE OF LABORATORY ANIMALS WITH SOFT TISSUE DEFECTS
Authors: Sahab Haidar A. . , Tretiak S. I. , Nedzved M. K. , Baranov E. V. , Nadyrov E. A. , Lobanok E. S. , Vasilevich I. B.
Published: September 2022

The paper presents the results of experimental studies in laboratory animals with a simulated infected wound. Their treatment included the application of mesenchymal stem cells (MSCs) derived from adipose tissue. It was established that the application of MSCs was accompanied by the regeneration features of skin defects, i.e. the inflammation was cut short faster, the wound healing processes accelerated, as well as the stimulation of growth of skin appendages was observed. The received results may be used as a basis for further research and development aimed at the introduction of cellular technologies for the treatment of wound defects of various etiology into clinical practice.
THE COMPARATIVE ANALYSIS OF EMPIRIC-CALCULATED ASSESSMENT METHODS FOR ACCUMULATED DOSES IN POPULATION OF BELARUS RESIDING ON THE CHERNOBYL RADIONUCLIDE CONTAMINATED TERRITORIES
Authors: Chunikhin L. A. , Vlasova N. G. , Drozdov D. N. , Bortnovsky V. N.
Published: September 2022

The article presents the comparative analysis of assessed accumulated doses in the population residing on the territories contaminated with Chernobyl radionuclides conducted by methods valid in the Republic of Belarus and the Russian Federation. The technique, used in Belarus, was modified on basis of WBC-measurements and TL-dosimetry. It was shown that there were essential differences in the assessment of internal radiation dose, conducted by Byelorussian and Russian methods. The comparison of the internal dose estimations, conducted according to the method used in Belarus and its modification, showed differences since 1993. The assessments of external doses that were conducted by Russian methods differed from the results of Byelorusian methods. In order to use the United Chernobyl Register data, the methods of the dose assessment have to be coordinated. Сравнение оценок дозы внутреннего облучения, проведенных по методике Беларуси, и ее модификации, показало различия, начиная с 1993 г. Оценки дозы внешнего облучения, которые проводились по методике РФ, также отличаются от результатов белорусских методик.
MODERN MEANS AND APPROACHES TO TREATMENT FOR DIABETES MELLITUS TYPE 2
Authors: Kapliyeva M. P.
Published: September 2022

The treatment for diabetes mellitus (DM 2), aimed to achieve firm compensation of the disease on the indicators of fasten, postprandial and night glycemia, as well as glycohemoglobin (HbА1С) must include the participation of the physician and, first of all, the patients themselves. The most important principle of DM 2 etiotropic treatment is a changed lifestyle that includes dietotherapy and physical activity mode. They are prescribed to all DM 2patients without exception since the moment of diagnosis and until the end of active life in any scheme of medical DM 2 treatment, but requires a lot of patients` effort. The DM 2 treatment is concentrated on patogenetical section: to overcome insulin resistance and stimulate endogen insulin secretions, but in case of its exhaustion, substitutive insulin therapy is used. All antidiabetic medicines are divided into three main groups: insulin sensitisers used for insulin resistance; secretagogue which stimulate insulin secretion and insulines.
PHENOMENON OF SELF-CONCEPTION IN THE VIEWPOINT OF ADDICTIVE PERSONAL BEHAVIOR
Authors: Trafimchyk Zh. I.
Published: September 2022

This article covers the study of the phenomenon of «Self-conception» in the viewpoint of addictive personal behavior. The article presents the results of theoretical analysis of the problem of addictive behavior and self-conception of personality in national and foreign psychology. The study suggests a theoretical model of structural organization of personal self-conception.
DISEASES OF PANCREATIC GLAND IN CHILDREN
Authors: Kozlovsky A. A.
Published: September 2022

The present-day diagnosis and treatment for the diseases of pancreatic gland in children is one of the most complex problems of clinical gastroenterology. There is a tendency of the increased prevalence of these diseases and at the same time their diagnosis presents significant difficulties and is often accompanied by diagnostic errors. Thereby, the timely diagnosis of the diseases of pancreatic gland and their adequate treatment will make it possible to improve the disease prognosis and decrease the complications rate.
LOCAL FEATURES AND PHENOTYPES OF ANTIBIOTIC RESISTANCE OF PSEUDOMONAS AERUGINOSA
Authors: Osipov V. A. , Tapalskiy D. V.
Published: September 2022

Objective : to estimate the resistance prevalence of P. aeruginosa to antipseudomonal antibiotics and reveal metallo-beta-lactamases producers among carbapenem resistant clinical isolates. Materials and methods. The subject of the study is clinical isolates of P. aeruginosa resistant to antibacterial drugs. The resistance of P. aeruginosa clinical isolates to antipseudomonal antibiotics was estimated, antimicrobial resistance phenotypes and associated resistance variants were analyzed, and production of metallo-beta-lactamases was detected using phenotypical screening method. Results. High levels of P. aeruginosa resistance to the most of antibacterial drugs, except carbapenems, were revealed. The local features of antimicrobial resistance in different hospitals were established. A total of 19 metallo-beta-lactamase producers were isolated in 6 hospitals of three republican regions. All metallo-beta-lactamase producers have the same phenotype, indicating of clonal prevalence. No carbapenem resistant isolates was resistant to colistin. Conclusion. It is necessary to carry out multi-facet research aimed at the detection of carbapenem resistance mechanisms and epidemiological marking of resistant isolates in order to reveal epidemically significant P.aeruginosa metallo-beta-lactamase producing clones in time and to develop the infection control measures to restrain its circulation.
HEREDITARY HEMOCHROMATOSIS (case from clinical practice)
Authors: Paltsev I. V. , Kalinin A. L. , Achinovich S. L. , Anikeev O. I.
Published: September 2022

In article the case of hereditary hemochromatosis, revealed at elderly patient at outcome stage to liver cirrhosis is presented. Clinical, laboratory and morphological signs of disease are described. Insignificant expressiveness of clinical and laboratory displays and late diagnostics of the given condition is noted.
ALGORITHM OF RATIONAL ANTIBACTERIAL THERAPY OF PYELONEPHRITIS AND ITS MICROBIOLOGICAL BASIS
Authors: Lagun L. V. , Tapalskiy D. V.
Published: September 2022

Aim of research. To study resistance levels to different antibiotics of pyelonephritis etiologic agents, revealing of extended-spectrum beta-lactamases producers among agents and development of an algorithm of microbiological diagnostics and rational antibacterial therapy of pyelonephritis. Materials and methods. A total of 115 clinical strains of enterobacteria (70 - Escherichia coli , 35 - Proteus spp. , 10 - Klebsiella pneumoniae ) isolated from urine of patients with acute and chronic pyelonephritis were included in the research. The sensitivity of microorganisms to antibacterial agents was determined by disc diffusion method. The extended-spectrum beta-lactamases (ESBL) production was carried out by using the double disk diffusion method. The genodetection of ESBL of various groups in etiologic agents of pyelonephritises was determined by means of polymerase chain reaction (PCR). Results. The resistance of microorganisms, etiologic agents of pyelonephritises to antibiotics of various groups was evaluated. The study revealed high prevalence of extended-spectrum β-lactamases producers concerning to CTX-M group. Conclusion. The data obtained during the study about levels and resistance mechanisms of enterobacteria to antibacterial agents of different groups were the base for development of the algorithm of microbiological diagnostics and rational antibacterial therapy of pyelonephritis.
Comparative Characteristics of CLINICAL and LABORATORY FEATURES of SECONDARY and DE NOVO acute myeloid leukemia in children
Authors: Romashevskaya I. P. , Savva N. N. , Litvinko N. P. , Aleinikova O. V.
Published: September 2022

Secondary leukemias in children in most cases are acute myeloid leukemia (AML) cases induced by chemotherapy and/or radiotherapy and by other chemical mutagens after treatment of malignant neoplasms (MN) or acquired aplastic anemia (AAA). The purpose of this study was to evaluate the clinical and laboratory features of secondary AML. The study included 9 patients with secondary AML and 128 patients with de novo AML. The girls revealed secondary AML more often. The largest percentage of secondary AML cases was observed in the age group from 3 to 10 (age median: 11.5), the most frequently registered morphology was M1-M2, but statistically significant differences with de novo AML were not found (p > 0,05). When comparing the clinical manifestations, no significant differences were detected (p > 0,5). Meanwhile, the pathology of chromosome 7 with secondary AML was significantly the most prevalent (p ≤ 0,01).
МETHODOLOGY FOR STUDIES OF DRUG SENSITIVITY OF LEUKEMIA CELLS
Authors: Svirnovskiy A. I.
Published: September 2022

The preclinical diagnostics for drug sensitivity of malignant blood cells contributes to administration of adequate treatment and its individualization. The scheme of laboratory studies and significance of each stage has beenpresented in the article
FECAL LACTOFERRIN IN DETECTION OF COLON CANCER AT VARIOUS STAGES OF ITS DEVELOPMENT
Authors: Mihaylova E. I. , Filipenko N. V.
Published: September 2022

The purpose of the study was to evaluate the efficacy of detection of colorectal cancer at different stages of its development on the basis of fecal lactoferrin. Subject of study: 48 patients with colorectal cancer, 46 patients with irritable bowel syndrome and 25 healthy volunteers were included in the study group. The results of the study: it was found that fecal lactoferrin was diagnostically reliable with areas under the curve (AUC) at 0,940 ± 0,0327 and AUC: 0,956 ± 0,032, respectively in non-invasive diagnosis of early and late-stage colorectal cancer, and was not inferior to the immunochemical test for faecal occult blood (AUC: 0,939 ± 0,0342 and AUC: 0,931 ± 0,0393, p = 0,73 and p = 0,62,respectively).
РARASITOGENIC DISEASES IN THE REPUBLIC OF BELARUS AND IN THE REPUBLIC OF YEMEN (literature review)
Authors: Anichkin V. V. , Martyniuk V. V.
Published: September 2022

Ascariasis and echinococcosis are severe parasitogenic diseases. The quarter of the whole world population is infected with ascariasis. Ascariasis and echinococcosis are widely spread in the Middle East, India, Africa, Northern America, New Zealand, Australia, Turkey and Northern Europe. The comparative analysis of the most prevalent parasitogenic diseases followed by surgical complications is of great interest in non-endemic (Belarus) and endemic (Yemen) countries. This analysis results make it possible to receive reference data on tactics for surgery of parasitogenic diseases complications in abdominal cavity. The topicality of this problem is related to the prevalence of helminthiasis, in particular intestinal ascariasis in both Belarus and Yemen as well as the high frequency rate for recurrent cases of this pathology. Taking into account the fact that 5-7 % of the patients with this diagnosis have complications requiring operation, which does not always have good effect because helminthes continue parasitizing, the elaboration of new combined treatment methods (surgical and chemicotherapeutic) for this pathology is urgent and has great medical and social importance.
MEDICO-SOCIAL CHARACTERISTICS OF PATIENTS DIAGNOZED AS HIV-POSITIVE
Authors: Zaporovannyi Yu. B.
Published: September 2022

This article analyzes the medical social features of the patients diagnosed by the Medico-social Rehabilitation Commission of Experts as HIV-positive. It showed that the majority of them were of working age, and approximately two-thirds of them were men, and one-third women. Primary disablement in this pathology is very prevalent and makes up 75,2 %. In recent years, there has been a definite tendency towards an increase of the number of patients with this diagnosis.
ACUTE DISORDER OF BRAIN BLOOD CIRCULATION IN А PATIENT WITH CHRONIC HCV INFECTION (clinical case)
Authors: Maybogin A. M. , Nedzved M. K. , Tereshkov D. V.
Published: September 2022

The present article describes a clinical case of ischemic cerebral infarction in а female patient with chronic HCV-infection. Although the prevalence of this pathology does not seem to be very high in comparison with that in general population, it remains life-threatening and must be well studied as one of the possible neurologic complications of chronic HCV infection concordant to mixed cryoglobulinemia, the most prevalent anhepatic HCV manifestation. However, the etiology and peculiarities of visceral cryoglobulinemia manifestations in chronic HCV infection need further research, which makes this problem extremely actual in the present-day HCV treatment.
HUBUNGAN DURASI GADGET DENGAN EMOSIONAL ANAK USIA PRASEKOLAH DI PAUD NAURA LOSUNG BATU KOTA PADANGSIDIMPUAN
Authors: Napitupulu Natar Fitri , Napitupulu Mastiur
Published: September 2022

ABSTRAK

Durasi gadget yang berlebihan dapat mengganggu perkembangan anak, terutama pada anak usia  prasekolah. Pada anak usia  prasekolah  perkembangan emosi merupakan salah satu sangat penting dalam perkembangan anak karena kemampuan anak dalam mengelola emosi dan mengenal emosi sangat dibutuhkan ketika anak memasuki lingkungan di sekitarnya yang memiliki pengaruh terhadap perilaku anak. Tujuan penelitian untuk mengetahui apakah ada Hubungan Durasi Penggunaan Gadget Dengan Emosional Anak Usia Prasekolah Di Paud Naura Losung Batu Kota Padangsidimpuan. Jenis Penelitian kuantitatif dengan menggunakan Desain penelitian croos sectional study dan jumlah Populasi penelitian sebanyak 54 orang. Tehnik pengambilan Sampel penelitian dengan tehnik snowballing sampling sebanyak 24 orang dan Uji statistik yang digunakan yaitu Chi square. Hasil penelitian mayoritas durasi gadget diperoleh 17 orang (70.8%) dan minoritas durasi gadget sebanyak 3 orang (12.5%). Diharapkan penelitian ini menambah wawasan memberi masukan dan sebagai bahan perbandingan mengenai hubungan durasi gadget dengan emosional anak  khususnya penerapan mutu pelayanan kesehatan anak.

Excessive duration of gadgets can interfere with child development, especially in preschoolers. In preschool age children, emotional development is very important in child development because the child's ability to manage emotions and recognize emotions is needed when children enter the surrounding environment that has an influence on children's behavior. The purpose of the study was to determine whether there was a relationship between the duration of gadget use and the emotions of preschool-age children at Paud Naura Losung Batu, Padangsidimpuan City. This type of research is quantitative using a cross sectional study design and the number of research population is 54 people. The sampling technique used was the snowballing sampling technique as many as 24 people and the statistical test used was Chi square. The results of the study were that the majority of gadget durations were obtained by 17 people (70.8%) and the minority of gadget durations by 3 people (12.5%). It is hoped that this research will add insight to provide input and as a comparison material regarding the relationship between gadget duration and children's emotions, especially the application of the quality of child health services.

Keywords: Gadget Duration, Children's Emotional, Preschool
HUBUNGAN BEBAN KERJA DENGAN KINERJA PEGAWAI DI RUANG SEKRETARIAT DINAS KESEHATAN PROVINSI ACEH
Authors: Rosita Sri
Published: September 2022

The workload experienced by employees of the Aceh Provincial Health Office Secretariat room during the Covid-19 pandemic increased, not only inside the building but also outside the building. such as the formation of a task force to deal with covid-19 so that the workload of employees outside the building and inside the building increases. The purpose of this study was to determine the relationship between workload and employee performance in the Aceh Provincial Health Office secretariat room. This research is a descriptive analytic study with a cross sectional design. This research was conducted from October 7 to November 2 2020 in the Aceh Provincial Health Office secretariat room using the interview method. The research sample was 86 respondents with total sampling technique. Univariate and bivariate data analysis. From the results of the chi-square statistical test, it can be concluded that there is a relationship between workload and employee performance with a p value of 0.01. It is hoped the leadership in the secretariat room, is to evaluate the workload assigned to employees and according to their fields of expertise so that good performance can be maintained.
HUBUNGAN PENGETAHUAN DAN SIKAP WANITA USIA SUBUR (WUS) TERHADAP PEMBERIAN IMUNISASI TERANUS TOXOID DI DESA BATANG BARUHAR JAE KECAMATAN PADANG BOLAK KABUPATEN PADANGLAWAS UTARA TAHUN 2020
Authors: Aswan Yulinda
Published: September 2022

tubuh terhadap suatu penyakit dengan memasukkan sesuatu ke dalam tubuh agar tubuh tahan terhadap penyakit yang sedang mewabah atau berbahaya bagi seseorang. Imunisasi terhadap suatu penyakit hanya akan memberikan kekebalan atau resistensi pada penyakit itu saja, sehingga untuk terhindar dari penyakit tidak akan sakit atau sakit ringan . Imunisasi yang diberikan kepada wanita usia subur dan ibu hamil adalah imunisasi TT yang berguna untuk mencegah terjadinya tetanus. Kasus tetanus banyak dijumpai di sejumlah negara tropis dan negara yang masih memiliki kondisi kesehatan rendah. Pada tahun 2018 WHO memperkirakan 59.000 kematian bayi karena tetanus, angka tersebut sudah menurun sebesar 90% jika dibandingkan dengan tahun 2019 dimana terjadi 787.000 kematian karena Tetanus Metode penelitian adalah deskriptif kerelational dengan menggunakan pendekatan Cross Sectional, Sampel diambil dengan menggunakanTotal Sampel. Jumlah  sampel sebanyak 43 orang. Analisis data menggunakan uji Chi Square. Hasil penelitian menunjukkan pengetahuan 0,002 (0,002 < 0,05) dan sikap 0,000 (0,000 < 0,05). Kesimpulan penelitian adanya Hubungan   pengetahuan dan sikap Wanita Usia Subur terhadap pemberian imunisasi Tetanus Toxoid  Di Desa Batang Baruhar  Jae Kecamatan Padang Bolak Kabupaten Padang Lawas Utara Tahun 2020. Disarankan Wus yang bertempat tinggal di desa Batang Baruhar pemahaman tentang manfaat  Imunisasi dan mau melakukannya.

Kata Kunci :  Pengetahuan, Sikap, Imunisasi Tetanus Toxoid

 

ABSTRACT

Immunization gave the body immunity against a disease by inserting something into the body so that the body is resistant to diseases that are endemic or dangerous for someone. Immunization against a disease would only provide immunity or resistance to disease, so that you will not get sick or get mild illness. The immunization given to women of childbearing age and pregnant women was TT immunization which was useful for preventing tetanus. Tetanus cases were often found in a number of tropical countries and  2018 WHO estimates 59,000 infant deaths due to tetanus, this figure has decreased by 90% when compared to 2019 where there were 787,000 had due to Tetanus. The research method is descriptive relational using the Cross Sectional approach, the sample was taken using a total sample. The number of samples is 43 people. Data analysis using Chi Square test. The results showed knowledge was 0.002 (0.002 <0.05) and 0.000 attitude (0.002 <0.05). The conclusion of this research was that there was a relationship between the knowledge and attitudes of women of fertile age towards giving Tetanus Toxoid immunization in Batang Baruhar Jae Village, Padang Bolak District, North Padang Lawas Regency in 2020. It is recommended that Wus who lives in Batang Baruhar village understand the benefits of immunization and wanted to do it.

Keywords: Knowledge, Attitude, Tetanus Toxoid Immunization
The Related Factors of unmet neet phenomena in fertile coule in desa pasir matogu kecamatan angkola muaratail kabupaten tapanuli selatan
Authors: Siregar Nurelilasari
Published: September 2022

The high number of unmet needs is a population phenomenon that becomes an important aspect that needs to be considered in the development of the family planning movement in the future. The purpose of the study was to analyze factors related to the occurrence of Unmet Need in Couples of Childbearing Age (PUS) in Pasir Matogu Village, Angkola Muaratais District, South Tapanuli District in 2021. This research is analytical with a cross-sectional design. The population in this study was all women of childbearing age couples who were married, had children, and lived together with 104 husbands, which was sampled by 51 people. The collected data is analyzed using the Chi-Square test. The results showed that income, employment status, parity, knowledge of KB and support from husbands were significantly related to the incidence of unmet family planning needs. It is recommended for kb officers in the working area of Puskesmas Pintu Padang, especially in Pasir Matogu Village, so that efforts to apply the KB program need to be improved and focused on unmet need groups. Efforts that can be made is by providing KIE for both husband and wife through home visits by each village midwife.
e HUBUNGAN PENGGUNAAN ALAT PELINDUNG DIRI (APD), SIKAP,DAN PERILAKU PETANI SAAT PENYEMPROTAN PESTISIDA PADA KELOMPOK TANI
Authors: Entianopa Entianopa -
Published: September 2022

Dalam implementasi pemakaiaan alat pelindung diri, faktanya masih banyak petani yang tidak mau memakai APD. Ada banyak faktor yang berhubungan dengan penggunaan APD pada petani. Beberapa faktornya adalah faktor pengetahuan, sikap, masa kerja, perilaku, dan umur. Desain penelitian adalah cross sectional. Penelitian dilakukan pada Kelompok tani sumber Tani di Kelurahan Paal Merah Kota Jambi pada bulan juli tahun 2021. Sampel penelitian adalah para petani yang tergabung dalam kelompok tani sumber tani sebanyak 36 orang. Teknik pengambilan sampel menggunakan teknik Total Sampling. Instrumen yang digunakan adalah kuesioner. Data dianalsis menggunakan uji Regresi Logistik. hasil akhir analisis multivariat regresi logistik karena variabel sikap, ketersediaan APD, mempunyai p value < 0,05, dengan demikian ke dua variabel mempunyai pengaruh terhadap Prilaku penggunaan APD. Meningkatkan pengetahuan dan sikap perilaku petani dengan cara memberi informasi tentang manfaat APD melalui metode inovatif berdasarkan hasil penjajakan yang relevan secara berkesinambungan (parsipatoris) agar meningkatkan penggunaan APD.
HUBUNGAN PERILAKU SUAMI TERHADAP DUKUNGAN PEMBERIAN ASI EKSLUSIF PADA BAYI DI WILAYAH KERJA PUSKESMAS BATANG PANE II
Authors: Wahyuni Iin , Aswan Yulinda , Pohan Sakinah Yusro
Published: September 2022

Pemberian Air Susu Ibu (ASI) eksklusif merupakan salah satu upaya untuk meningkatkan status gizi anak dalam 1000 Hari Pertama Kelahiran. Bayi yang diberikan ASI ekslusif dapat mencapai pertumbuhan perkembangan dan kesehatan optimal. Pemberian ASI Eksusif sangat dipengaruhi perilaku kesehatan berupa, pengetahuan, tidakan, sikap, mencakup dukungan suami. Tujuan penelitian untuk mengetahui hubungan perilaku suami terhadap dukungan pemberian ASI ekslusif pada bayi di Wilayah Kerja Puskesmas Batang Pane II Kecamatan Halongonan Timur Kabupaten Paluta Tahun 2020. Jenis penelitian penelitian kuantitatif dengan desain cross sectional study. Populasi yaitu seluruh ibu yang mempunyai bayi berusia ≤6 bulan yang ada di Wilayah Kerja Puskesmas Batang Pane II Kecamatan Halongonan Timur Kabupaten Paluta yang sebanyak 90 orang. Sampel yaitu seluruh ibu yang mempunyai bayi berusia ≤6 bulan yang ada di Wilayah Kerja Puskesmas Batang Pane II Kecamatan Halongonan Timur Kabupaten Paluta sebanyak 90 orang dengan menggunakan metode total sampling. Analisa yang digunakan adalah uji Chi Square. Hasil penelitian ini menunjukkan bahwa perilaku suami (p= 0,001), pengetahuan suami (p= 0,000), sikap suami (p= 0,003), tindakan suami (p= 0,001) berhubungan dengan dukungan pemberian ASI ekslusif. Kesimpulan diperoleh bahwa perilaku suami berhubungan dengan dukungan pemberian ASI ekslusif. Saran bagi suami agar memberikan perhatian lebih terhadap dukungan pemberian ASI ekslusif.