bluuebunny/crossref_metadata_2025 huggingface dataset:
Failures of intensive treatment of multiple organ failure: pathophysiology and the need for personalization
Authors: Grigoryev Evgeny V , Shukevich D. L. , Plotnikov G. P. , Kudryavtsev A. N. , Radivilko A. S.
Published: May 2019

Multiple organ failure (MOF) is the most severe outcome of the critical care patients of any reason (sepsis, trauma, ischemia and reperfusion), the mortality rate with this syndrome has no tendency to decrease. The review article offers, first of all, an introduction to the key research areas in which the MOF theory is currently developing (alarmines, mitochondrial dysfunction, barrier insufficiency, immunological and neurological conjugation, forms of programmed cell death, induced immunosuppression, resolution of inflammation). Studies prove the feasibility of introducing a personalized approach to the diagnosis of MOF by substantiating the endophenotype of the critical care patients on the basis of a complex of immunological, genomic and clinical indicators.
Prolegomena to the System-Anthropological Theory of Thinking
Authors: Nelyubin N. I.
Published: May 2019

The article features preliminary "conceptual optics" necessary for understanding the problem of thinking from the perspective of post- non-classical psychology. The study focused on methodological gaps  in the formulation and solution of the problem of thinking within the  framework of positivist-oriented approaches. They proved to be  connected with building a one-dimensional-instrumental view of a  thinking person as a gnoseological subject. The view is often reduced to an operator of cognitive processes, artificially derived from the  framework of one’s own historicity and existential datum of life. It  reveals the existential-anthropological givenness of human thinking,  taken in the context of one’s own life world and one’s own life relationships, as well as in the context of the trans-perspective of becoming and complicating its "cogital identity". The author substantiates the view that thinking of a holistically  understood person acts as a form of life-realization, and all thinking events are evidence of one’s attempts to thematisation and  constitution of one’s "cogital identity" and resistance to "co- deindividualization". The study revealed a need to expand the  research focus of the psychology of thinking, so that its positive heuristics were not limited to the mental apparatus of the  averaged operator of cognitive processes, but include existential givenness and the capabilities of a living historical  personality that realizes meaningful existential relations with itself  and the world in thinking.
Psychological Media Competence of Parents of Primary School Children
Authors: Skorova L. V. , Chernikova E. V.
Published: May 2019

The paper features sychological media competence of parents on the basis of ideas about psychological media competence as a meso- level phenomenon, differing complex composition. The psychological  media competence of parents is considered in the structure of their  psychological competence, including cognitive, practical, and  reflexive components. The cognitive component includes knowledge  that allows one to take part in the media communication and analyze  the influence of media texts on the psyche of children. The  reflexive component is the awareness of internal changes after  interacting with media. The practical component is represented by  the ability to realize competence in interaction with children. The  procedure for diagnosing these components was developed based on the research method of “Psychological media competence of parents  of primary school pupils”. The first part was represented by  ituations  describing behavior and actions of primary school pupils in  media sphere and identifying how parents react to them. The second part included watching an animated film, answering questions that  reveal how parents understood the effect of the cartoon on children’s emotional state and behavior, and writing a letter to the main  character of the cartoon on behalf of their children. The analysis of  the psychological media competence study involved a method of  expert assessments. The results indicate a certain use of  constructive ways of reaction to situations, which are related to  information search via internet and watching destructive video. The  parents proved to underestimate effect of various media on children  and demonstrated problems in assessing and meaningful discussion of the media texts with children.
Hate Speech as a Manipulative Means of Forming the Inimical Image of Russia in British and American Mass-Media (viewed from the Aspect of the English Language Taught to Russian Students)
Authors: Karpukhina T. P.
Published: May 2019

The research features manipulative technologies aimed at forming the inimical image of Russia in British and American mass-media. The inimical conception, when intentionally built, is predetermined by the already existing stereotype of an enemy, whose most evident and manifest features are singled out and enclosed into the image thus constructed. The stereotype, in its turn, can be traced back to the most ancient archetype of a hostile member of a different tribe, perilous to the group he intends to destroy. The image of Russia created by the British and American mass-media is overloaded with negative connotations as contrasted with a highly positive self-image of the British and Americans. Russia is presented as an aggressor that interferes with other countries’ affairs, while its opponents, as they claim, fight against terrorism and meet other global challenges. Nothing is farther from the truth but the manipulative technologies  employed help to drive this idea into the readers’ heads. The British and American media-language turns to “hate speech” whenever they refer to Russia. Most effective, though over-exploited, is its constant repetition. All this serves as a substitute for actual facts, logic, and arguments. The question arises: what should EFL students do with the language material that often misinforms or insults their country? The answer is obvious: never degrade yourself by attacking or insulting the opponents. They might be entrapped in the war rhetoric or the stereotypes and be truly convinced of the Russians’ hostility. Consider the facts, but not emotions, and manipulation will miss you or your friendly attitude to Englishmen and Americans as a target.
Preposition "по" in Russian Scientific Texts in the Meaning "to Act in Accordance with Something, on the Basis of Something"
Authors: Naumova N. G.
Published: May 2019

The paper describes the semantics of the preposition "по", which is the most ambiguous and common preposition of the modern Russian language. Thus, it reveals a tendency to blurred semantics, which makes a deeper consideration of this problem quite relevant. The author analyzed scientific literature on this issue and built a classification its meanings. The semantic analysis and statistical calculations were conducted in the basis of scientific texts. The preposition proved to be used mostly in the meaning of adverbial modifier of manner "to act in accordance with something, on the basis of something". Within this meaning, a number of semantic shades were highlighted: to be defined according to some parameter; act on the basis of certain data, facts; act in accordance with a certain way of organizing the phenomenon; act on the basis of someone's will (decision), desire; act in accordance with certain official documents and procedures; to be defined according to a certain naming method; to be defined on the basis of some measurement method. The analysis can improve the semantic structure of the preposition "по" in modern Russian.
Interpersonal Relations of the Civil Servants with the Different Level of Social Normativity
Authors: Dukhnovsky S. V.
Published: May 2019

The paper features the problem of the interpersonal relations of the civil servants with the different level of social normativity. Harmony / disharmony of the interpersonal relations caused by a social and psychological distance between the interacting subjects prove to be the indicators of personnel risk for the organization. A change of a distance manifests of personnel risk, whereas a disharmony of the interpersonal relations in the business sphere poses a threat of personnel safety. Various empirical researches showed that regulatory civil servants seek to build such an acceptable distance in interpersonal interaction that would provides trust, emotional proximity, and a readiness for joint activity. On the contrary, non-regulatory government employees build a larger distance according to their personal traits. They reveal a deeper trust in themselves than in the partner, a lesser emotional proximity and no compatibility orientation. For regulatory employees, personnel riskis in a narrowing the distance, which may result in mixing the business and emotional relations, e.g. relations without concern for the status of the partner in the team. For non-regulatory employees, risk can manifest in an excessive distancing from colleagues, formalization of the relations, as well as criticism and depreciation of the partner. The empirical data obtained can be used for the development of personal and professional qualities of the civil servants, in particular for formation of flexible skills of a social and psychological distance in interpersonal interaction. It is important to use the principle of the differentiation assuming ability to differentiate forms of relationship and to build new interrelations between them.
Transabdominal sonography comparison with transvaginal sonography
Authors: Nausheen Fauzia , Iqbal Javed , Faruqi Naheed Jamal
Published: May 2019

Aims & Objectives: Transvaginal sonography (TVS) comparison with trans-abdominal sonography (TAS) in the diagnosis of pelvic masses Study Design: Retrospective descriptive study conducted at Gynae clinic Jinnah Hospital Lahore with collaboration of radiology department Materials and Methods: Transvaginal Sonogram was compared with transabdominal sonogram in hundred women referred for evaluation of pelvic masses from gynae clinic. All the women were interviewed regarding their age, parity, duration of mass and associated symptoms. Diagnosis was based on the combination of clinical, sonographic (TVS, TAS) and surgical correlation. Both ultrasound modalities were compared for the details about the internal architecture and diagnostic information. Results: Most common age group with pelvic masses was between 26-35yrs. TVS was more sensitive for both uterine and adnexal masses. Sensitivity of TAS was 65% and TVS was 88%. There was a significant difference in diagnosing true positive cases by trans-vaginal approach. (P value < 0.001) Specificity of TAS was 89% and TVS 86% for both uterine and adnexal masses. Image quality was better in 87% of cases with trans-vaginal approach and 5% of cases with trans-abdominal approach and it was equivalent in 8% of cases. There was a significant difference in the image quality between two modalities (P value < 0.001). Regarding anatomical details TAS was better in 12% of cases and TVS was better in 28% of cases and both were equivalent in 60% of cases, Diagnostic information of these two modalities was almost equivalent. TAS was better in 7% of cases and TVS was better in 8% of cases and both were equivalent in 85% of cases Conclusion: The results suggest that TVS has considerable advantage over conventional TAS in evaluation of pelvic masses in women.
An Experience with Colorectal Carcinomas
Authors: Khan Khalid Javed , Chohan Shabbir , Hassan Ammara , Randhawa Tanveer Hussain
Published: May 2019

This prospective study was conducted at Sir Ganga Ram Hospital over a period of three years. All patients presenting with colorectal carcinoma were studied and included in the study. Age of the patients included in the study ranged from 18 to 74 years. Gender distribution was 12 males and 17 females. The lesions were identified in the anal canal in 3 cases and in the rectum in 9 cases. At the rectosigmoid junction in 1 case, in the splenic flexure, transverse colon and ascending colon had lesions in 3, 5, 2 cases respectively. Six lesions were identified in the caecum. All of these patients were managed surgically according to the lesion location.
Calidad del agua de la parte baja del río Córdoba (Magdalena, Colombia), usando el ICA-NSF
Authors: Fontalvo Julio Fernando Antonio , Tamaris-Turizo Cesar E.
Published: May 2019

La evaluación de la calidad del agua de fuentes fluviales a través del estudio de variables físicas, químicas y microbiológicas es considerada como una herramienta que permite conocer el estado de contaminación. Una de las formas de evaluar estos sistemas a través de la integración de variables ambientales mediante índices como el ICA-NSF. Por tanto, el objetivo de este trabajo fue evaluar la calidad fisicoquímica de las aguas en del río Córdoba en su parte baja a través ICA-NSF y analizar los plaguicidas organoclorados más comunes. Se definieron seis sitios se muestreo, en cada una de ellas se midieron parámetros físicos, químicos y microbiológicos. Además, se determinó el nivel de concentración de los principales contaminantes, considerando el impacto que causan en el río y se estableció la calidad del agua por medio del ICA-NSF durante los periodos de sequía y lluvias entre el 2010 y el 2011. El ICA-NSF varió entre 52,6 durante las lluvias en “Muelle carbonífero” y 72,4 en el periodo seco en “Paso de los anillos” indican que la calidad del agua categorizó entre regular y buena, respectivamente. De las variables evaluadas, los coliformes fecales mostraron altos valores en los seis sitios (entre 2974 y 4940 NMP/100 ml), registros que sobrepasaron los límites permisibles para el consumo humano y la protección de flora y la fauna por la legislación colombiana. Los resultados mostraron una variación temporal (entre periodos climáticos) y una alta uniformidad espacial del río en los sitios de muestreo. En ninguno de los muestreos se encontraron residuos de plaguicidas organoclorados. Los resultados evidenciaron que la variación temporal (periodos de lluvias vs. sequías) reflejó de mejor manera los cambios en la calidad del agua del río Córdoba en su parte baja.
Apuntes sobre la importancia ecológica, ambiental y social de la arenca Triportheus magdalenae (Steindachner, 1878). Un ejemplo de endemismo invisibilizado
Authors: Valdelamar Villegas Juan Carlos
Published: May 2019

La arenca (Triportheus magdalenae) es una especie endémica de Colombia que habita principalmente la cuenca del río Magdalena-Cauca. En la presente revisión se integra la información de los pocos reportes científicos en los que se ha incluido a la especie, con el propósito de resaltar su importancia ecológica, ambiental y social. Los resultados revelaron que T. magalenae habita principalmente en humedales de agua dulce con bajos valores de dióxido de carbono y acidez moderada. La especie juega un papel importante en el entramado trófico de los ecosistemas acuáticos como regulador del plancton, a partir del cual es posible que obtenga la energía y nutrientes necesarios para su ciclo de vida, que ocurre de forma asincrónica y multiporcional. Además de su importancia ecológica y ambiental, la arenca históricamente ha sido fuente de proteína para muchas poblaciones que habitan en la cuenca, y actualmente ha sido identificado el uso potencial de algunos de sus derivados para aplicaciones en la industria alimenticia y farmacéutica. Sin embargo, la actual presión pesquera y ambiental puede estar comprometiendo la viabilidad de su población en el futuro
Applicability of Instability Index for In vitro Protein Stability Prediction
Authors: Gamage Dilani G. , Gunaratne Ajith , Periyannan Gopal R. , Russell Timothy G.
Published: May 2019

Background:

The dipeptide composition-based Instability Index (II) is one of the protein
primary structure-dependent methods available for in vivo protein stability predictions. As per this
method, proteins with II value below 40 are stable proteins. Intracellular protein stability principles
guided the original development of the II method. However, the use of the II method for in vitro
protein stability predictions raises questions about the validity of applying the II method under
experimental conditions that are different from the in vivo setting.

Objective:

The aim of this study is to experimentally test the validity of the use of II as an in vitro
protein stability predictor.

Methods:

A representative protein CCM (CCM - Caulobacter crescentus metalloprotein) that
rapidly degrades under in vitro conditions was used to probe the dipeptide sequence-dependent
degradation properties of CCM by generating CCM mutants to represent stable and unstable II
values. A comparative degradation analysis was carried out under in vitro conditions using wildtype
CCM, CCM mutants and two other candidate proteins: metallo-β-lactamase L1 and α -S1-
casein representing stable, borderline stable/unstable, and unstable proteins as per the II predictions.
The effect of temperature and a protein stabilizing agent on CCM degradation was also tested.

Results:

Data support the dipeptide composition-dependent protein stability/instability in wt-CCM
and mutants as predicted by the II method under in vitro conditions. However, the II failed to
accurately represent the stability of other tested proteins. Data indicate the influence of protein
environmental factors on the autoproteolysis of proteins.

Conclusion:

Broader application of the II method for the prediction of protein stability under in
vitro conditions is questionable as the stability of the protein may be dependent not only on the
intrinsic nature of the protein but also on the conditions of the protein milieu.
Antimicrobial Peptides and Vaccine Development to Control Multi-drug Resistant Bacteria
Authors: Baindara Piyush , Mandal Santi M.
Published: May 2019

Antimicrobial resistance (AMR) reported to increase globally at alarming levels in the recent past. A number of potential alternative solutions discussed and implemented to control AMR in bacterial pathogens. Stringent control over the clinical application of antibiotics for a reduction in uses is a special consideration along with alternative solutions to fight against AMR. Although alternatives to conventional antibiotics like antimicrobial peptides (AMP) might warrant serious consideration to fight against AMR, there is a thriving recognition for vaccines in encountering the problem of AMR. Vaccines can reduce the prevalence of AMR by reducing the number of specific pathogens, which result in cutting down the antimicrobial need and uses. However, conventional vaccines produced using live or attenuated microorganisms while the presence of immunologically redundant biological components or impurities might cause major side effects and health related problems. Here we discussed AMPs based vaccination strategies as an emerging concept to overcome the disadvantages of traditional vaccines while boosting the AMPs to control multidrug resistant bacteria or AMR. Nevertheless, the poor immune response is a major challenge in the case of peptide vaccines as minimal antigenic epitopes used for immunization in peptide vaccines.
Lytic Polysaccharide Monooxygenase from Aspergillus fumigatus can Improve Enzymatic Cocktail Activity During Sugarcane Bagasse Hydrolysis
Authors: de Gouvêa Paula Fagundes , Gerolamo Luis Eduardo , Bernardi Aline Vianna , Pereira Lucas Matheus Soares , Uyemura Sergio Akira , Dinamarco Taisa Magnani
Published: May 2019

Background:

Lytic Polysaccharide Monooxygenases (LPMOs) are auxiliary accessory
enzymes that act synergistically with cellulases and which are increasingly being used in secondgeneration
bioethanol production from biomasses. Several LPMOs have been identified in various
filamentous fungi, including Aspergillus fumigatus. However, many LPMOs have not been characterized
yet.

Objective:

To report the role of uncharacterized A. fumigatus AfAA9_B LPMO.

Methods:

qRT-PCR analysis was employed to analyze the LPMO gene expression profile in different
carbon sources. The gene encoding an AfAA9_B (Afu4g07850) was cloned into the vector pET-
28a(+), expressed in the E. coli strain RosettaTM (DE3) pLysS, and purified by a Ni2+-nitrilotriacetic
(Ni-NTA) agarose resin. To evaluate the specific LPMO activity, the purified protein peroxidase
activity was assessed. The auxiliary LPMO activity was investigated by the synergistic activity in
Celluclast 1.5L enzymatic cocktail.

Results:

LPMO was highly induced in complex biomass like sugarcane bagasse (SEB), Avicel®
PH-101, and CM-cellulose. The LPMO gene encoded a protein comprising 250 amino acids, without
a CBM domain. After protein purification, the AfAA9_B molecular mass estimated by SDSPAGE
was 35 kDa. The purified protein specific peroxidase activity was 8.33 ± 1.9 U g-1. Upon
addition to Celluclast 1.5L, Avicel® PH-101 and SEB hydrolysis increased by 18% and 22%, respectively.

Conclusion:

A. fumigatus LPMO is a promising candidate to enhance the currently available enzymatic
cocktail and can therefore be used in second-generation ethanol production.
Advances in Targeted Gene Delivery
Authors: Begum Anjuman A. , Toth Istvan , Hussein Waleed M. , Moyle Peter M.
Published: May 2019

Gene therapy has the potential to treat both acquired and inherited genetic diseases. Generally,
two types of gene delivery vectors are used - viral vectors and non-viral vectors. Non-viral gene delivery
systems have attracted significant interest (e.g. 115 gene therapies approved for clinical trials in 2018;
clinicaltrials.gov) due to their lower toxicity, lack of immunogenicity and ease of production compared
to viral vectors. To achieve the goal of maximal therapeutic efficacy with minimal adverse effects, the
cell-specific targeting of non-viral gene delivery systems has attracted research interest. Targeting
through cell surface receptors; the enhanced permeability and retention effect, or pH differences are
potential means to target genes to specific organs, tissues, or cells. As for targeting moieties, receptorspecific
ligand peptides, antibodies, aptamers and affibodies have been incorporated into synthetic nonviral
gene delivery vectors to fulfill the requirement of active targeting. This review provides an overview
of different potential targets and targeting moieties to target specific gene delivery systems.
The Role of Oxidative Stress, Adhesion Molecules and Antioxidants in Preeclampsia
Authors: Haram Kjell , Mortensen Jan Helge , Myking Ole , Magann Everett F. , Morrison John C.
Published: May 2019

Oxidative stress is a consequence of reduction in the antioxidant capacity and excessive production of reactive oxygen and nitrogen species (ROS). Oxidative agents, which are overproduced due to ischemic-reperfusion injury in the placenta, may overwhelm the normal antioxidant activity. This imbalance is a key feature in the pathogenesis of preeclampsia. A decrease in glutathione peroxidase (GPX) activity is associated with the synthesis of vasoconstrictive eicosanoids such as F2-isoprostanes and thromboxane, which are known to be upregulated in preeclampsia. Biochemical markers of lipid peroxidation, such as malondialdehyde and F2-isoprostane in the placenta, are also increased. Adhesion molecules participate in the pathophysiology of preeclampsia by contributing to a reduced invasion by the trophoblast and increased vascular endothelial damage. Superoxide dismutase (SOD), catalase (CAT) and GPX play important roles counteracting oxidative stress. Other antioxidant factors participate in the etiology of preeclampsia. Levels of antioxidants such as Lycopene, Coenzyme 10, as well as some vitamins, are reduced in preeclamptic gestations.
Overview of the ways to reduce telemetric information redundancy
Authors: Baibekova F. N. , Podoltsev V. V. , Bespalova N. M. , Sologubova L. A.
Published: May 2019

The redundancy of telemetric information significantly complicates the real-time processing of the information flows. To speed up the telemetry processing process, the methods for telemetric information redundancy reduction should be applied in order to reduce its flows entering the monitoring systems while maintaining a high speed of processing and reliability of the information. The article provides an overview of the methods for reduction of telemetric information redundancy, such as the increase in PHY-rate of telemetry channel, the Huffman algorithm, the batch mechanism for generation and transmission of telemetry information, the adaptive difference algorithm, the algorithm for transmission of the information based on its representation by residual images, Golomb-Rice codes, reversible compression method. The advantages and disadvantages of each of them are considered. Recommendations on the use of multi-level telemetry information compression system are given, which makes it possible to effectively combine target data compression algorithms that give the highest compression ratio depending on the type of telemetry information transmitted.
Crianças indígenas Guarani Nhandewa no Norte do Paraná: aprendizagens culturais e escolares
Authors: Cassulla Marcella Hauanna , Faustino Rosangela Celia
Published: May 2019

A criança indígena, na organização sociocultural de cada povo, tem formaspróprias de aprender, recebendo cuidados, orientação e atenção dos parentes. Nacultura Nhandewa, todos os espaços da aldeia são espaços de aprendizagem dascrianças. Os mais velhos, os tudjás, assim como os Txamõi e as Djaryi, sabedoresdas tradições, as repassam às novas gerações em situações e espaços propícios,como a Oy Guatsu. Neste texto apresentamos e discutimos elementos da educaçãoda criança Guarani Nhandewa, observados e registrados, especialmente, emsuas vivências em eventos culturais, em terras indígenas do norte do Paraná.Evidenciou-se que os professores Nhandewa, com apoio de suas comunidades,têm buscado articular os conhecimentos escolares aos conhecimentos ancestrais,no espaço escolar e nos eventos culturais nas aldeias, configurados comomomentos de significativas aprendizagens para as crianças Guarani.
APRESENTAÇÃO
Authors: Vieira Filho Raphael
Published: May 2019

Pós-modernidade é um termo polissêmico e que ainda provoca muitas discussões acadêmicas sobre seus marcos temporais e teóricos. Suas ligações e posições políticas, os temas suscitados, as utilizações provocadas por essa polissemia e a falta de precisão temporal provocam a inclusão e exclusão de autores e pensadoresnas coleções e coletâneas organizadas desde a década de 1930. A primeira utilização do termo pós-modernismo, no mundo acadêmico, foi de fala hispânica e tinha a estética. O que está ao lado dessas discussões, e que interessa ao campo da Educação, é responder: que saberes devem ser valorizados nos currículos diante do desafio das novas tendências? Quantos passagens são possíveis entre a escola e a sociedade? O que e como incluincluir neste contexto social em transformação?
Evaluation of Manual and Electronic Health-care associated infections (HAIs) Surveillance: a prospective multi-center study (Preprint)
Authors: Chen Wensen , Chen Wensen , Zhang Weihong , Yang Yue , Liu Yun
Published: May 2019

UNSTRUCTURED

A large multi-center study including 21 tertiary general hospitals and 63 wards were recruited to evaluate the impact of electronic surveillance and interaction platform system (SIPS) for health-care associated infections (HAIs). We collected 4098 consecutive patients and found that the hospitals installed with SIPS significantly increased work efficiency of infection control practitioners (ICPs) achieving satisfactory diagnostic performance of HAIs with 0.73 for sensitivity, 0.81 for specificity and 0.81 area under the curve (AUC). However, there were significant heterogeneity own to regions, time of SIPS installation, departments and sample size.
Effect of nutrition improvement program implementation on stunting in children under two years old
Authors: Handayani Yolanda , Makful Martya Rahmaniati
Published: May 2019

PurposeThe first thousand days of life is a critical momentum where children from the age of 2 years need the best nutrition for brain development. This study examined the effect of appropriate timing of supplementary feeding and vitamin A consumption on nutritional status of children below age of twoMethodThe design of this study is cross sectional. The sample in this study is based on data of the Nutritional Status Monitoring 2017 which is amounted to 27.208, consisting of pregnant women who took iron folate supplementation (TTD); mother gave early breastfeeding initiation, exclusive breastfeeding, and supplementary food; children who received vitamin A; and children who get height measurement by age.ResultsThe odds of mothers not providing supplementary feeding to children aged 7-23 months have a short nutritional status 1,137 times greater than mothers who provide supplementary feeding. While the Vitamin A variable has odds ratio 0,659 significantly, the odds of children not getting Vitamin A have short nutritional status 0, 659 times greater than children who received Vitamin A. Conclusion: The risk of stunting occurs in a period of 6 to 24 months due to the period for growth in height. Health workers at the primary health care should inform mothers to provide supplementary food and vitamin A at the 6-24 month of age.
Pelatihan Rumah Ramah Literasi untuk Meningkatkan Keterampilan Stimulasi Literasi pada Orang Tua
Authors: Harahap Dinda Permatasari , Martani Wisjnu
Published: May 2019

Abstract. This research developed “Rumah Ramah Literasi” training program to improve parent’s stimulation of literacy skills using environmental print as a media. The research hypothesis is the “Rumah Ramah Literasi” training program can improve parent’s stimulation of literacy skills. The experimental design employed in this present study is The Untreated Control Group Design with Pretest and Posttest Samples.The subject of this research are 18 mothers which is 9 mothers in experimental group and 9 mothers in control group.The data were analyzed by using Mann Whitney U-Test. The result of this study was found that gain score literacy stimulation was significantly higher, U(n=18) =0,001, p<0,05 in the experimental group (M=14) than in the control group (M=5).This indicates that “Rumah Ramah Literasi” training program could improve parents’ literacy stimulation. Effect size of “Rumah Ramah Literacy” training program was 0,84. Keywords: environmental print; literacy; literacy stimulation; parents
Efektivitas Terapi Kognitif Perilakuan untuk Meningkatkan Efikasi Diri Abstinen NAPZA
Authors: Ratih Erga Patragave , Utami Muhana Sofiati
Published: May 2019

Abstract. The research aimed to determine the effectiveness of Cognitive-Behavior Therapy to increase self efficacy towards multiple drug addicts. The One-Group Pretest-Posttest Design was used in the research. The participants were 6 people who were the resident of Drug Rehabilitation Center “K” located in Sleman, Special Region of Yogyakarta. Pretest and posttest measure by Drug Avoidance Self-Efficacy Scale. Data were analyzed by non-parametric statistics, used Wilcoxon analysis. The results showed significance of 0.0135. Acording to the results, there was an indication that Cognitive-Behavior Therapy’s module was able to increase self efficacy among drug addicts. Keywords: cognitive-behavior therapy; multiple drugs; self efficacy
Three Dimensional Structural Modelling of Lipase Encoding Gene from Soil Bacterium Alcaligenes sp. JG3 Using Automated Protein Homology Analysis
Authors: Nataningtyas Dilin Rahayu , Raharjo Tri Joko , Astuti Endang
Published: May 2019

Bacterial lipases have significant potential to be used as the biocatalyst for many chemical reactions. In this study, a novel gene encoding lipase was isolated from an Alcaligenes sp. JG3. A pair of designed primer has successfully isolated 1 kb (LipJG3) that shares 98% identity towards lipase from Alcaligenes faecalis during sequence analysis. By using in silico tools, LipJG3 was related to the transporter protein sequences. Three highly conserved regions consisting of EASGSKT, VILLD, and LSGGQQQRVAIA were found. These regions were known as ATP-binding signature at Walker-A and Walker-B motifs and the S signature of ABC transporter family respectively. In addition, the 3-D structure of LipJG3 has been suggested but the role of the catalytic triad residues have been not fully understood.
Microwave Assisted Synthesis and Evaluation of Toxicity and Antioxidant Activity of Pyrazoline Derivatives
Authors: Jasril Jasril , Teruna Hilwan Yuda , Aisyah Aisyah , Nurlaili Nurlaili , Hendra Rudi
Published: May 2019

Four pyrazoline analogues, 3-(4-methoxyphenyl)-5-naphthalene-1-yl-1-phenyl-4,5-dihydro-pyrazole (3), 3-(4-methoxyphenyl)-5-naphthalene-1-yl-4,5-dihydro-1H-pyrazole (4), 3-(2-methoxyphenyl)-5-naphthalene-1-yl-1-phenyl-4,5-dihydro-pyrazole (5) and 3-(2-methoxyphenyl)-5-naphthalene-1-yl-4,5-dihydro-1H-pyrazole (6) were synthesized via intermolecular cyclization between substituted chalcones and hydrazine derivatives. The compounds were synthesized in two steps. In the first step, the chalcones were synthesized by Claisen-Schmidt reaction. In the second step, they were cyclized with some hydrazine derivatives to form pyrazolines by using glacial acetic acid as a catalyst and assisted by microwave irradiation. The toxicity analysis showed that compound 1 and 2 were toxic with LC50 values of 11.47 and 0.97 μg/mL, respectively. Furthermore, only compound 6 showed high antioxidant activity by using DPPH with an IC50 value of 4.47 μg/mL.
Effect of Free Fatty Acid Pretreatment to Yield, Composition and Activation Energy in Chemical Synthesis of Fatty Acid Methyl Ester
Authors: Mohd Alias Nor Saadah , Veny Harumi , Hamzah Fazlena , Aziz Noorhaliza
Published: May 2019

Transesterification of waste cooking oil (WCO) for fatty acid methyl ester synthesis using calcium oxide (CaO) as a catalyst with absence and presence of free fatty acid (FFA) pretreatment (untreated and pretreated) prior to reaction have been investigated. The preliminary study was started from theoretical stoichiometric amount molar ratio of methanol to oil. This preliminary experiment showed that indeed, in transesterification with the chemical catalyst the molar ratio of methanol to oil should be exceeding the theoretical stoichiometric molar ratio, due to the fast reversible reaction. The highest FAME content of 81% was achieved at a temperature of 75 °C with pretreated FFA. The composition of methyl ester with pretreated FFA was affected by temperature, where increasing temperature leads to increasing of methyl oleate as major methyl ester in the product. The relation of temperature dependence was further studied by Arrhenius law correlation. It is shown that activation energy was affected by pretreatment of fatty acid. The activation energy (Ea) of transesterification with untreated and pretreated free fatty acid were found as ± 16 kJ/mol and ± 68 kJ/mol, respectively. Unlike untreated FFA, the Ea of transesterification with pretreated FFA was within the range of activation energy for transesterification for the base catalyst. This study showed that methyl ester synthesis was best obtained when FFA was pretreated prior to transesterification. In addition, WCO is a potential feedstock for biodiesel production since it is biodegradable, economic, environmentally friendly and abundantly available.
Combustion Synthesis Ironmaking: Investigation on Required Carbon Amount in Raw Material from the Viewpoint of Adiabatic Flame Temperature Calculation
Authors: Abe Keisuke , Kurniawan Ade , Sanada Masafumi , Nomura Takahiro , Akiyama Tomohiro
Published: May 2019

Combustion synthesis (CS) is a simple and very fast method to synthesize a target material. New ironmaking method via the CS using carbon-infiltrated iron ore was proposed, and the possible conditions for the method were investigated. Adiabatic flame temperatures (Tad) of the CS reaction, maximum reachable temperatures in an adiabatic system, were calculated to estimate the sample temperature during the CS. To reach the adiabatic temperature of 1811 K, 23.9, 27.9, and 29.3 wt.%-C were required for Fe2O3, Fe3O4, and FeO, respectively. When the carbon amount is higher than the calculated one, molten iron which is separated from slag components should be obtained via the CS.
Pyrolusite Bioleaching by an Indigenous Acidithiobacillus sp KL3 Isolated from an Indonesian Sulfurous River Sediment
Authors: Retnaningrum Endah , Wilopo Wahyu
Published: May 2019

The manganese bioleaching process of pyrolusite from Kliripan, Indonesia using Acidithiobacillus sp KL3 was investigated. The influence pulp densities of pyrolusite (0.01, 0.02, 0.03 and 0.05 g/cm3) on the bioleaching processes were studied for 16 days. The reduction on pH values, the increasing of oxidation-reduction potential (ORP), sulfate and manganese concentration were analyzed. The manganese bioleaching mechanism of pyrolusite by the strain was monitored using Scanning Electron Microscope-Energy Dispersive-X-ray Spectroscopy (SEM-EDX). The results indicated that 0.02 g/cm3 of pyrolusite was considered to be the optimal pulp density for manganese bioleaching process. During this process, pH values decreased, furthermore resulted in increasing of ORP, the concentration of sulfate and manganese. SEM-EDX analysis clearly showed the evidence of directly bacterial cell attachment into the surface of pyrolusite. Extracellular polymeric substances (EPSs) were further founded on that surface. Sulfur elemental was oxidized by the strain which was then confirmed of resulting in solubilized manganese.
The Potentials of an Integrated Ultrasonic Membrane Anaerobic System (IUMAS) in Treating Sugar Cane Wastewater
Authors: Nour Abdurahman Hamid , Zaki Yasmeen Hafiz , Mohamed Hybat Salih , Rassem Hesham Hussein
Published: May 2019

Excess levels of organic and inorganic matters in the discharge from sugarcane mill effluent (SCME) wastewater, causes the earnest environmental issue. In this study, a single unit integrated ultrasonic membrane anaerobic system (IUMAS) has been investigated for industrial sugarcane wastewater treatment. As the “Membrane-fouling” is one of the main constraints of IUMAS which eventually reduce the processing ability. In the present study, most researchers resort to cost reduction. IUMAS was alternatively applied as an economical approach for SCME wastewater treatment. The application of “Multiple-analysis” methods (COD, BOD, TSS) and three kinetic models during the treatment, suggested the specific range of organic loading rate to produce biogas. The result showed the increased methane gas production up to 80% in the biogas, with 94 -96% of COD removal efficiency from the SCME wastewater. Results concluded the effective efficiency of IUMAS to reduce the membrane fouling and treatment of SCME wastewater as well as enhanced production of methane gas.
Growth and Yield Characters of Two Cashew (Anacardium occidentale L.) Cultivars at Different Ages in Baubau City, South-East Sulawesi Province
Authors: Aliyaman Aliyaman , Indradewa Didik
Published: May 2019

Baubau City is one of the cashew (Anarcadium occidentale L.) producer area in Southeast Sulawesi with area of 820 ha. This large area of cashew cultivation was not compensated with the productivity caused of low production. An effort to overcome this problem is identifying the growth and yield characters of cashew to apply the good agricultural practices for cashew plantation. The objective of this research was to determine the growth and yield of two cashew varieties at different tree ages; and to identify the relationship between the characters and the productivity of cashew trees in Baubau City. This research was arranged by oversite design with 2 varieties (the cashew with red pseudo-fruit and the cashew with yellow pseudo-fruit), 4 ages of cashew plant (5 years old, 17 years old, 26 years old, 37 years old) and 5 replications. The results showed that both varieties had no significantly different on growth and yield characters. At 37 years old, cashew trees still demonstrated the increasing of the productivity due to the increasing of growth and yield component i.e. plant biomass, the number of flower, the number of cashew nut per plant and cashew nut weight per kernel.
Pengembangan potensi lokal ikan menjadi nugget dan abon ikan untuk meningkatkan kesejahteraan masyarakat dan menurunkan angka kejadian stunting di Kanigoro, Saptosari, Gunungkidul
Authors: Ngaisyah Raden Roro Dewi , Adiputra Andre Kusuma
Published: May 2019

Kanigoro Village is blessed abundantly with great potential for fish resources development. Its strategic location by the seashore also poses an opportunity for Kanigoro to become a center for local home-based culinary industries focusing on local fish, such as fish nuggets and floss (shredded meat), which are rich sources of animal protein. Despite the plentiful local protein sources, a high prevalence of stunting continues to plague Kanigoro Village, reaching up to 48.2%. Developing fish-based culinary industries may become a means to reduce the stunting rates as well as to improve the economic status of the villagers. This project aimed to develop the fish-based local food processing into nuggets and floss to improve family economies and nutritional status in Kanigoro Village through a community-based approach. It began with the sharing of the project plan to gain support from the community. The team collaborated with local Kanigoro organizations, namely posyandu cadres and women's group. The training was given to the women's group on marketing, such as providing nutritional information on the packages, developing attractive packaging, and introducing marketing niches. Posyandu cadres were trained to motivate the villagers to increase fish consumption. After the training, the groups conducted meetings with the local women under the supervision of the team. In the meeting sessions, they encouraged villagers to eat more fish. Through the training, the local women acquired new knowledge on product enhancement, starting from improved processing hygiene, upgraded packaging, provision of nutritional information, and innovative marketing ventures. In the gatherings, posyandu cadres were able to deliver motivation to augment fish consumption. They could measure the height and weight of children under five correctly, enabling them to identify children with stunting. The knowledge and skills acquired from this project will equip the local villagers to prevent and reduce stunting prevalence in Kanigoro Village.
The Clash of Traditional and Modern Cultures in the Novels Samdae (Three Generations) by Yeom Sang Seop and Tetralogi Buru (Buru Quartet) by Pramoedya Ananta Toer
Authors: Trihtarani Febriani Elfida
Published: May 2019

This study analyzes Korean writer Yeom Sang-seop's colonial-era novel Samdae (Three Generations) (1931) and Pramoedya Ananta Toer's Tetralogi Buru (Buru Quartet). Although Korea and Indonesia have different cultures, they share a history of colonization by imperial countries. The purpose of this study is to analyze the writers' cultural differences as they appear in these novels. Yeom Sang-seop’s Samdae (Three Generations) is shown to capture the conflict of traditional and modern cultures. In this novel, characters who follow traditional culture consider customs and honor very important. Meanwhile, the characters in Pramoedya’s quartet consider honor to be important. In Yeom Sang-seop’s novel, those seeking modernity hold only modern ideas and ultimately fall victim to consumerism. On the other hand, in Pramoedya’s novels, while characters with modern ideas do exist, they are not trapped in a world of consumerism. Yeom Sang-seop seeks a solution to escape colonialism through one character who is not interested in traditional culture but also shows no significant interest in modern culture. He instead supports socialism, which can be considered an attempt to avoid the downsides of modernity. In the novels of Pramoedya, one character Minke faces a similar situation. Through his national organizing activities, he shows the possibility that Indonesia can break free of colonialism.
The Impact of Property Management on the Value of Residential Product in Saudi Arabia
Authors: Al-Otaibi Omar M. , Alzamil Waleed S.
Published: May 2019

This paper discusses the impact of property management in maintaining the value of residential product in Saudi Arabia. The paper reviewed a comparison of two property models: the first is managed by the property management system, and the second is managed by the owner only. In addition, the field questionnaire was used and distributed to a sample of the study community consisting of 125 real estate management institutions and real estate office in Riyadh. The results of the analysis indicate that property management contributes to raising the quality of the residential product and maintaining its market value. The residential product which managed by the property management system loses 10% of its value after 5 years. On the other hand, the product that managed by the owner loses more than 50% of its real value after 5 years. The paper proposes to strengthen cooperation between governmental and private institutions to establish a Real Estate Data Center (REDC) for the classification of residential properties subject to the criteria of management, quality and economic cost.
Comparison of conservative treatment with appendectomy for acute uncomplicated pediatric appendicitis: a meta-analysis
Authors: Bi Le-wee , Yan Bei-lei , Yang Qian-yu , Cui Hua-lei
Published: May 2019

Aim:
We aimed to compare conservative treatment with surgery for uncomplicated pediatric appendicitis to estimate effectiveness and safety.
Methods:
Data recorded until September 2018 were searched, and relevant academic articles from PubMed, EMBASE, the Cochrane Library and other libraries were selected. STATA version 13.0 (Stata Corporation, TX, USA) was used for statistical analysis.
Results:
We identified nine eligible papers. The study reported a significant difference in the success rate of treatment in 1 month and in 1 year, and no difference in the incidence of complications. The patients with fecaliths showed low treatment efficacy in conservative treatment group (p < 0.05).
Conclusion:
Standardized conservative treatment as inpatients for pediatric appendicitis is safe and feasible. Appendectomy was the better choice for patients with fecaliths.
Desarrollo y productividad agrícola en América Latina: el problema de la medición.
Authors: Sotelsek Salem Daniel Federico , Laborda Castillo Leopoldo
Published: May 2019

El crecimiento de la productividad agrícola puede tener consecuencias nada triviales a la hora de mejorar el consumo de subsistencia y de elevar los ingresos procedentes de este sector de la economía. Para autores como Fulginiti y Perrin (1998) o Nin y otros (2003) es posible que tanto los métodos como los datos hasta ahora empleados hayan interpretado de forma errónea la productividad de la agricultura en algunos países sesgando sus medidas. Este es precisamente el propósito de este trabajo y para ello se hará uso del desarrollo metodológico llevado a cabo por Oâ€™Donnell (2008) para intentar resolver los problemas anteriormente señalados y contrastarlo con los resultados de las metodologías no paramétricas tradicionales. Mediante índices transitivos de Lowe se estima el cambio de la Productividad Total de los Factores (TFP en inglés), en este caso de la agricultura de algunos países de América Latina para el período 1990-2006. Los resultados obtenidos cuestionan la evidencia empírica obtenida en estudios precedentes. Finalmente se confirma la hipótesis sobre las diferencias de resultados de la productividad cuando se estiman mediante el concurso del índice de Malmquist y el de índices de Lowe.