bluuebunny/crossref_metadata_2025 huggingface dataset:
Acute and Transitional Care or Rehabilitation? Retrospective analysis of discharge planning from a municipal hospital in Switzerland
Authors: Kollbrunner Lara , Michael Rost , Insa Koné , Bettina Zimmermann , Yvonne Padrutt , Tenzin Wangmo , Simone Elger Bernice
Published: July 2019

Background

Due to rising health care costs, in 2012 Switzerland introduced SwissDRG, a reimbursement system for hospitals based on lump sums per case. To circumvent possible negative consequences like reduction in length of stay, acute and transitional care (ATC) was anchored into the law (Federal act on health insurance) in 2011. ATC as a discharge option is applicable to patients with no capacity for rehabilitation, but are unable to return home and are in need of temporary professional nursing care. ATC is associated with higher out of pocket costs to the patient than rehabilitation. Since social service workers are responsible for organizing discharge of patients with ongoing care needs after hospitalization, the aim of this study was to investigate how social service workers manage patient discharge in light of the new discharge option ATC.

Methods

Data was collected from 660 medical records of inpatients from Zurich's municipal hospital, Triemli, in 2016. We compared patients discharged to ATC and rehabilitation using inferential statistics and qualitatively analyzed written statements from social service workers.

Results

Our results showed that patients discharged to rehabilitation had a higher total number of discussions, but a shorter duration of discussions. Patients discharged to rehabilitation faced more delays, above all because of unavailability of free places. Conflicts concerning discharge arose mainly because of costs, discharge placement and too early discharge.

Conclusions

Our findings demonstrate how important social service workers are in explaining to patients about different discharge options. The newness of SwissDRG and ATC is still likely to cause longer discussion times and, consequently, more workload for social service workers. Only a small fraction of patients disagreed with their place of discharge, mostly due to financial reasons.
Feasibility and Desirability of Scaling up Community –based Health Insurance (CBHI) in rural communities in Uganda. Lessons from Kisiizi hospital CBHI scheme.
Authors: AYEBAZIBW ALEX KAKAMA
Published: July 2019

Abstract
Background
Community-based health Insurance (CBHI) schemes have promoted equitable healthcare access and raised additional revenue for health sector, in addition to forming foundations for National Health Insurance schemes in many countries. Non-profit making organisations characterised by solidarity, voluntary membership and prepayment for health care.
Kisiizi hospital CBHI scheme has 41,500 registered members since 1996, organised in 210 community associations known as ‘Bataka’ or ‘Engozi’ societies. Members pay annual premium fees and a co-payment fee before service utilisation.
This Study aimed at exploring the feasibility and desirability of scaling up CBHI in Rubabo County, with objectives of; exploring community perceptions and determining acceptability of CBHI, identifying barriers and enablers to scaling up CBHI and documenting lessons regarding CBHI expansion in a rural community.

Method: Descriptive study using qualitative methods. Key informant interviews and Focus Group Discussions (FGD) were used in data collection. Participants were selected from three villages with differing levels of insurance coverage.
Twenty two key informant interviews were conducted using semi-structured questionnaires. Three FGD for scheme members and three for non-scheme members were conducted. Data was analysed using thematic approach.
Results:
Scaling up Kisiizi hospital CBHI is desirable because; it conforms to the national social protection agenda, conforms to society values, offers a comprehensive benefits package, and is a better healthcare financing alternative for many households.

Secondly, scaling up Kisiizi hospital CBHI is largely feasible since a strong network of community associations exist, trusted quality of services at Kisiizi Hospital, affordable fees, and trusted leadership and management systems. However, scale up of the Kisiizi hospital CBHI is still limited by; long distances and high transport costs to Kisiizi hospital, low levels of knowledge about insurance, overlapping financial priorities at household level and inability of some households to pay insurance fees.

Conclusions
CBHI scheme implementation requires the following considerations; Conformity with local society values, conformity with national policies/guidelines, a comprehensive benefits package, trusted quality of healthcare services, affordable fees, and trusted leadership and management systems.
Key words
Community-based Health Insurance, Universal Health Coverage, Health financing, Enrolment
vacA genotypes and EPIYA motifs of Helicobacter pylori in patients with atrophic and non-atrophic gastritis
Authors: Escalante Santiago , Navarrete Cesar , Nuñez Daniela , Reyes Jorge , Zabala Andres , Pazmiño Galo
Published: July 2019

Summary

Background

Helicobacter pylori is the main microorganism causing gastrointestinal diseases, such as chronic gastritis, peptic ulcer, MALT lymphoma, among others. The presence of the s1/m1 genotype of the vacA gene and EPIYA phosphorylation motifs of the cagA gene have been linked to the production of prolonged gastric inflammation. This study determines the presence of these virulence genotypes and their relationship with atrophic gastritis.

Methods

We included 231 patients with a history of dyspepsia undergoing upper gastrointestinal endoscopy. Samples of gastric tissue were taken to establish, through molecular techniques, the presence of H. pylori by amplifying the ureA and flaA2 housekeeping genes; in addition, the alleles of signal (s) and of the middle region (m) present in the vacA gene were amplified; and by sequencing the repeating patterns of the tyrosine phosphorylation motifs within the Glu-Pro-Ile-Tyr-Ala (EPIYA) motifs of the cagA gene were also amplified. A chi-square test was performed in order to establish the relationship between the virulence genes and the degrees of gastric injury.

Results

A total of (91/231) samples were positive for H. pylori, of which (57/91) amplified the cagA gene and (66/91) the vacA gene. 81.8% (54/66) of the positive samples for the vacA gene showed the combination of the s1/m1 alleles, associated mostly with atrophic gastritis (AG). The most frequent EPIYA motifs were ABC and ABCC, with 54.4% (31/57) and 40.4% (23/57) respectively. A relation of the genes with AG and its injury severity with a p>0.05 value was observed. The cagA +/vacA s1/m1+/EPIYA ABC pattern is found in most samples. A p=0.02 relationship was found between the presence of the vacA gene and the cagA gene.

Conclusions

The results show a higher proportion of gastric atrophy in patients infected with H. pylori. The sum of the pathogenicity factors such as the cagA+/vacA s1/m1+/EPIYA ABCC genotype increases the virulence potential of the microorganism, suggesting that the coexistence of these genes could result in an increase in the severity of the progression of inflammation that leads to precancerous lesions.
Real-time diagnostic yield of white light endoscopy, chromoendoscopy and magnifying endoscopy with narrow band imaging in the undiagnosed gastric lesions after Helicobacter pylori eradication
Authors: Tahara Tomomitsu , Horiguchi Noriyuki , Terada Tsuyoshi , Yoshida Dai , Okubo Masaaki , Funasaka Kohei , Nakagawa Yoshihito , Shibata Tomoyuki , Ohmiya Naoki
Published: July 2019

Background: Early-stage gastric cancer (EGC) after Helicobacter pylori (H. pylori) often confuse endoscopic diagnosis. We prospectively evaluated the real-time diagnostic yield of combining white light endoscopy (WLE), chromoendoscopy (CE), and magnifying endoscopy with narrow band imaging (ME-NBI) for undiagnosed gastric lesions after H. pylori eradication.
Methods: Using a retrospective data set, we conducted a consensus meeting to learn ME-NBI features of EGC after H. pylori eradication associated with diagnostic difficulty. Then, we prospectively evaluated the real-time diagnostic yield of WL, followed by CE, and ME-NBI in the diagnosis of 166 newly identified gastric lesions from 219 patients after H. pylori eradication.
Results: A consensus meeting characterized ME-NBI feature of EGC with diagnostic difficulty, as having irregular vessel patterns in only tiny area of the lesion. Among 166 undiagnosed gastric lesions in the prospective study, 22 neoplastic lesions (18 adenocarcinomas and 4 adenomas) were identified. In these lesions, diagnosed case was dramatically increased when combined with ME-NBI (98%) compared to WLE alone (54%) and CE with WLE (63%) (WLE+CE+ME-NBI vs. others, all P<0.0001). In the diagnosed cases, the diagnostic accuracy was also improved when combined with ME-NBI (99.4%) compared to WLE alone (92.2%: P=0.004) and CE with WLE (95.1%: P=0.03).
Conclusions: WLE combined with ME-NBI can improve the diagnostic yield of EGC in patients after H. pylori eradication. For precise diagnosis of EGC by ME-NBI, it is essential to detect irregular vessels.
Risk factors for peritonitis in patients on continuous ambulatory peritoneal dialysis who undergo colonoscopy: A retrospective multicentre study
Authors: Gweon Tae-Geun , Jung Sung Hoon , Kim Sang Woo , Lee Kang-Moon , Cheung Dae Young , Lee Bo-In , Choi Hwang
Published: July 2019

Background: Colonoscopy is associated with a risk of peritonitis in patients on peritoneal dialysis. However, no study has yet described the risk factors in play.
Methods: This was a retrospective multicentre study. The medical records of patients on continuous ambulatory peritoneal dialysis (CAPD) who underwent colonoscopy from January 2003 to December 2012 were analysed. We recorded demographic characteristics, colonoscopic factors, use of prophylactic antibiotics, and development of peritonitis. Colonoscopy-related peritonitis was defined as peritonitis developing within 1 week after colonoscopy. Demographic and clinical characteristics were compared between patients who did and those who did not develop peritonitis.
Results: During the study period, 236 patients on CAPD underwent colonoscopy, of whom 9 (3.8%) developed peritonitis. The rates of polypectomy/endoscopic mucosal resection were significantly higher in the peritonitis group than in the no peritonitis group (66.7 vs. 23.4%, p=0.009). Prophylactic antibiotics were prescribed before colonoscopy in 65 patients; none developed peritonitis. No patient who developed peritonitis received prophylactic antibiotics (p=0.067).
Conclusions: Advanced procedures including polypectomy or endoscopic mucosal resection increase colonoscopy-related peritonitis in patients on CAPD. Prophylactic antibiotics should be administered before colonoscopy to such patients.
Blood donors’ knowledge and attitude towards blood donation at North Gondar district blood bank, Northwest Ethiopia: a cross-sectional study
Authors: Enawgaw Bamlaku , Yalew Aregawi , Shiferaw Elias
Published: July 2019

Objective: Blood transfusion saves millions of lives. In Ethiopia, the need and the actual number of donations are not balanced. The actual reason is not clearly assessed however level of knowledge and attitude may be the main contributing factors. Thus, the current study aimed to assess blood donors’ knowledge and attitude towards blood donation at North Gondar district blood bank.
Results: Of 401 blood donors, 142 (35.4%) and 379 (94.5%) of them had adequate knowledge and positive attitude, respectively. About 343 (85.5%) of study participants had no previous experience of blood donation. Perceptions of fear of pain, medically unfitness to donate and lack of information on when, where and how to donate blood were mentioned as reason for not donating blood. Educational status and residence were significantly associated with knowledge while participants with secondary and higher education were more likely to have good attitude towards blood donation. Thus, blood banks and others should design strategies for health education regarding blood transfusion.
Keywords: Blood donation, Blood donors, Knowledge, Attitude, Gondar, Northwest Ethiopia
Comparison of Fructose and Glycerol as Plasticizers in Cassava Bioplastic Production
Authors: Mukuze Stephen , Magut Hillary , Mkandawire Frankson Lovemore
Published: July 2019

This research paper is an investigation into the effects of fructose and glycerol as plasticizers in cassava bioplastic production. The experiments were carried out at the University of Eastern Africa, Baraton Department of Chemistry. The objectives of the research were to produce cassava-based bioplastics in the University of Eastern Africa, Baraton Chemistry Department Laboratory, to investigate the use of fructose and glycerol as plasticizers in the production of the cassava-based bioplastics and to conduct physical and chemical quality tests on the bioplastics to determine which plasticizer is best for industrial use. A Randomized Complete Block Design (RCBD) was used in the experiments. The parameters measured were film thickness, density, moisture content, solubility in water, water absorption, swelling index, and biodegradability test. Overall, fructose as a plasticizer is recommended over glycerol and over fructose and glycerol.
Heavy metals sorption onto alluvial soil under various operational conditions
Authors: Fattah Bayan abdel , Mossad Mohamed , El-Etriby Hisham Kh.
Published: July 2019

The removal of lead Pb+2, copper Cu+2 and cadmium Cd+2 from aqueous solutions by alluvial soil (AL) as adsorbent has been investigated in a series of laboratory scale experiments under various operational conditions (solution pH, adsorbent dose, ions concentration and contact time). Characterization of AL has been carried out using infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The surface of AL beads is irregular with many spaces, channels and holes, which are helpful for mass transfer of metal ions into AL soil. The optimum ions removal can be achieved in alkaline solutions. Ions removal efficiency is directly related to contact time and adsorbant dose and inversely related to the initial ions concentration. Ion selectivity on AL followed the order of Pb+2 > Cu+2 > Cd+2. The results confirm that AL can remove heavy metals from wastewater efficiently, which is a cheap and environmentally friendly adsorbent. Langmuir and Freundlich isotherms fit the experimental data perfectly. The results indicate that the adsorption of pb+2, Cu+2 and Cd+2 ions is well fitted by the pseudo second-order kinetic model.
Expression Suppression and Activity Inhibition of TRPM7 Regulate Cytokine Production and Multiple Organ Dysfunction Syndrome During Endotoxemia: a New Target for Sepsis
Authors: Gatica Sebastian , Eltit Felipe , Santibanez Juan F. , Varela Diego , Cabello-Verrugio Claudio , Simon Felipe
Published: July 2019

Background:

Main pathological features detected during sepsis and endotoxemia include over-secretion of pro-inflammatory cytokines and multiorgan dysfunction syndrome (MODS). Unfortunately, current clinical efforts to treat sepsis are unsatisfactory, and mortality remains high. Interestingly, transient receptor potential (TRP) melastatin 7 (TRPM7) ion channel controlling Ca2+ and Mg2+ permeability is involved in cytokine production and inflammatory response. Furthermore, TRPM7 downregulation has been shown to alleviate local symptoms in some models of sepsis, but its effects at a systemic level remain to be explored.

Objective:

To test whether TRPM7 mediates cytokine production and MODS during endotoxemia.

Method:

Endotoxemic and sham-endotoxemic rats were subjected to pharmacological inhibition of TRPM7 using carvacrol, or to expression suppression by adenovirus delivery of shRNA (AdVshTRPM7). Then, cytokine and MODS levels in the blood were measured.

Results:

Inhibition of TRPM7 with carvacrol and suppression with AdVshTRPM7 were both efficient in inhibiting the over-secretion of pro-inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-12, in endotoxemic rats, without inducing downregulation in blood levels of antiinflammatory cytokines IL-10 and IL-4. Additionally, the use of carvacrol and AdVshTRPM7 significantly prevented liver and pancreas dysfunction, altered metabolic function, and hypoglycemia, induced by endotoxemia. Furthermore, muscle mass wasting and cardiac muscle damage were also significantly reduced by the use of carvacrol and AdVshTRPM7 in endotoxemic rats.

Conclusion:

Our results indicate TRPM7 ion channel as a key protein regulating inflammatory responses and MODS during sepsis. Moreover, TRPM7 appears as a novel molecular target for the management of sepsis.
The Association of Transcription Factor 7 like 2 Gene Polymorphism with Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus
Authors: Morgan Marianne Fathy , Salam Randa Fayez , Rady Normeen Hany , Alnaggar Alshaimaa Rezk L.R. , Ammar Soha Hamed , Ghanem Nashwa Said
Published: July 2019

Background:

The exact relationship between the different TCF7L2 gene polymorphisms
and the development of diabetic nephropathy (DN) remains unclear.

Objective:

To investigate the association of TCF7L2 rs12255372 (G/T) gene polymorphism and diabetic
nephropathy (DN) in patients with type 2 diabetes (T2D).

Methods:

100 patients with T2D (50 patients without DN and 50 patients with DN) and 50 age and
sex-matched healthy controls (HC) were enrolled in the study. Genotyping for the rs12255372 (G>T)
polymorphism in the TCF7L2 gene was performed by real-time PCR.

Results:

The rs12255372 polymorphism showed a statistically significant difference between HC and
patients with and without DN in both the genotype and allele frequency. However, the rs12255372
polymorphism genotype or allele frequency was not statistically different between patients with DN
and those patients without DN. The G allele was found to be higher in patients and the T allele was
higher in HC suggesting that the G allele was the risk allele for developing T2D &DN and that the T
allele was protective.

Conclusion:

rs12255372 TCF7L2 gene polymorphism was strongly associated with type 2 diabetes
mellitus and DN. The association between rs12255372 polymorphism and DN was a mere reflection of
a complicated diabetes mellitus rather than a direct independent association.
Synthesis, Antitumor Activity, Molecular Docking and DFT Study of Novel Pyrimidiopyrazole Derivatives
Authors: Fahim Asmaa M. , Elshikh Mohamed S. , Darwish Noura M.
Published: July 2019

Background:

In this investigation, 2-cyano-N-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl) acetamide (3) reacts with dimethylformamide dimethyl acetal (DMF-DMA) to afford the corresponding (E)- 2-cyano-3-(dimethylamino)-N-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylam-ide (4) utilizing microwave irradiation. The condensation reactions of acrylamide derivative 4 with hydrazine derivatives obtain pyrazole derivatives 6a and 6b; respectively. The synthesized compounds demonstrate in vitro antitumor activity against liver tumor cell line HepG2. Furthermore, additional studies were carried out on the most effective compound 6b to evaluate the potential interaction against 4hdq synthase complex with ΔE= -4.5Kcal/mol and with short distance = 1.727Å and 2.027Å, respectively. The comprehensive theoretical studies of compounds 6a and 6b is based on bond length, bond angles and energy gap HOMO-LUMO. In addition, the vibrational frequencies of optimized compounds 6a and 6b were examined through DFT/B3LYP/6+31G(d) basis set.

Methods:

In this research, synthesis of novel pyrimidiopyrazole derivatives calculated the computational studies to find suitable drug-receptor interactions and biological activity.

Results and Discussion:

The synthesized pyrimidiopyrazole derivative 6b exhibited high antitumor activity IC50 =12.6 μg/ml and interacted it with 4hdq synthase complex with ΔE=-4.5Kcal/mol and with short distance = 1.727Å and 2.027Å. Furthermore, the optimized compounds utilize Gaussian 09W.

Conclusion:

In the optimized pyrimidiopyrazole derivatives, 6b showed better antitumor activity HeG-2 against 5-flurouracil due to its energy and confirmed more potent of hydrogen bond interaction with protein pocket.
Simultaneous Determination of Four Monoamine Neurotransmitters and Seven Effective Components of Zaoren Anshen Prescription in Rat Tissue using UPLC-Ms/Ms
Authors: Li Rong , Wang Lin , Wang Xiao , Zhang Dian , Zhang Yafeng , Li Zhuo , Fang Minfeng
Published: July 2019

Background:

Zaoren Anshen Prescription (ZAP) is widely used as a classic Chinese Traditional
Medicine (TCM) prescription for the treatment of palpitations and insomnia in China. Some
studies have identified the main active components for its anti-insomnia effect and observed changes
of some endogenous components that are closely related to its anti-insomnia effect. However, simultaneous
determination of four monoamine neurotransmitters and seven effective components of ZAP and
the investigation of their distribution in tissues by using ultra-performance liquid chromatography
with tandem mass spectrometry (UPLC-MS/MS) have not been reported.

Methods:

An ultra-performance liquid chromatography with tandem mass spectrometry method was
developed and validated for simultaneous quantification of four monoamine neurotransmitters (norepinephrine,
dopamine, 5-hydroxy tryptamine and 5-hydroxyindoleacetic acid) and seven prescription
components (danshensu, protocatechualdehyde, spinosin, 6´´´ -feruylspinosin, salviaolic acid B, schisandrin
and deoxyschisandrin) in rats’ tissues. Tissue samples were prepared by protein precipitation
with acetonitrile. Chromatographic separation was carried out on a C18 column with a gradient mobile
phase consisting of acetonitrile and 0.01% formic acid water. An electrospray ionization triple quadrupole
concatenation mass spectrometer was set to switch between positive and negative modes in single
run time. All the components were quantitated by multiple-reaction monitoring scanning.

Results:

: The lower limits of quantitation for all analytical components were 0.78 ng/mL-1.99 ng/mL in
the heart, liver, spleen, lung, kidney and brain. All the calibration curves displayed good linearity (r >
0.99544). The precision was evaluated by intra-day and inter-day assays, and the relative standard
deviation (RSD) values were all within 12.67%. The relative errors of the accuracy were all within ±
19.88%. The recovery ranged from 76.00% to 98.78% and the matrix effects of eleven components
were found to be between 85.10% and 96.40%.

Conclusion:

This method was successfully applied to study the distribution of seven components from
ZAP and the concentration changes of four monoamine neurotransmitters after oral ZAP in six tissues.
2D Honeycomb Silicon: A Review on Theoretical Advances for Silicene Field-Effect Transistors
Authors: Chuan Mu Wen , Wong Kien Liong , Hamzah Afiq , Rusli Shahrizal , Alias Nurul Ezaila , Lim Cheng Siong , Tan Michael Loong Peng
Published: July 2019

Catalysed by the success of mechanical exfoliated free-standing graphene, two dimensional
(2D) semiconductor materials are successively an active area of research. Silicene is a monolayer
of silicon (Si) atoms with a low-buckled honeycomb lattice possessing a Dirac cone and massless
fermions in the band structure. Another advantage of silicene is its compatibility with the Silicon
wafer fabrication technology. To effectively apply this 2D material in the semiconductor industry, it
is important to carry out theoretical studies before proceeding to the next step. In this paper, an overview
of silicene and silicene nanoribbons (SiNRs) is described. After that, the theoretical studies to
engineer the bandgap of silicene are reviewed. Recent theoretical advancement on the applications of
silicene for various field-effect transistor (FET) structures is also discussed. Theoretical studies of
silicene have shown promising results for their application as FETs and the efforts to study the performance
of bandgap-engineered silicene FET should continue to improve the device performance.
Enheduana and the Invention of Authorship
Authors: Helle Sophus
Published: July 2019

The first known author, Enheduana, gained a central place in the literary culture of ancient Iraq long after the death of Sumerian, the language in which her poems were written. The essay argues that her authorship served to depict the Sumerian literary heritage as a tangible object that could be acquired by people who did not speak Sumerian as their native language, since Enheduana’s poems condensed a cacophony of independent traditions into a single entity. The process primarily took place in the city of Nippur in the troubled decades after 1740 BC, as the ancient scholars desperately needed to assert their importance. They did so by claiming special access to Sumerian literature, and authorship served as an ideal vehicle to represent that literature and that access. In short, Enheduana became a body and a bridge for Sumerian literature, condensing it into a single object and allowing it to move into a new cultural context.
POTENSI BIODIVERSITAS INDONESIA SEBAGAI INHIBITOR XANTINA OKSIDASE DAN ANTIGOUT
Authors: Yulian Muammar
Published: July 2019

Tendency for people to go back to nature and the government's policy to "Saintifikasi Jamu" prioritizing in degenerative diseases such as hyperglycemia, hypertension, hypercholesterolemia and hyperuricemia / gout is a condition that is highly prospective and has pushed for the development of research on medicinal plants-based biodiversity Indonesiasebagai state megabiodiversity. Results of research have shown that among the diversity of Indonesia's biodiversity as a potential inhibitor of xanthine oxidase (XO) and antigot is sidaguri (Sida rhombifolia L), celery (Apium graveolens L), fruits (Salacca R. edulis) varieties of Bangkok, ear- earrings (Acalypha indicaL.), and Bitter (Andrographis paniculata, Ness.). Ethanol extract of the herb sidaguri XO inhibitor has potential as indicated by the ability to dampen the activity of XO with IC50 values
PENCAPAIAN HASIL BELAJAR MELALUI PENUMBUHAN SIKAP MAHASISWA
Authors: Aswar Cut
Published: July 2019

Lecturer trying to grow and improve the positive attitude of students in the study of the course so that students can learn an increased vigor in the course. Indeed, the persistence of the negative attitude of students to a course, and it does not mean all the students to be negative towards a course, otherwise many students a positive attitude towards a subject that is learned. Lecturer of the course seeks to evoke the spirit of students to love a subject and trying to build a positive attitude towards the subject that he teaches. If the student has not been able to raise it toward a positive attitude among students, it is difficult for educators to develop students are knowledgeable and skilled in mastering a subject. For students who are positive or negative attitude is always the case in the learning of a subject, and even negative attitude is more dominant than positive attitude. Thus, the learning that educators are given less attractive, so that lecturers are less able to foster a positive attitude in the students learn a subject. That the lecturer of the course is able to actualize its role optimally in the process of learning a course undoubtedly positive attitude of students in the learning will become more prevalent among students. From the description above, the attitude of a person when used in the learning activities of the course, there will be individuals who love a subject (positive attitude) or being otherwise is not like a subject (a negative attitude). For students who have a positive attitude about a course will learn of their own accord and devote full attention to the matter of the course. Instead negative student attitudes about a course would lead to inactive students in learning activities and will ultimately negative effect also on a subject that is learned
DEGRADASI SENYAWA PARAQUAT DALAM PESTISIDA GRAMOXONE SECARA SONOLISIS DENGAN PENAMBAHAN ZnO
Authors: Arfi Febrina , Safni Safni , Abdullah Zaimi
Published: July 2019

Degradation of paraquat in gramoxone pesticide had been done by sonolysis with adding ZnO. Sonolysis method were performed using an ultrasound with frequency 50 kHz. The optimum condition of sonolysis were found at temperature 40oC. The percentage of degradation of 20 mg/L paraquat by sonolysisi method without adding ZnO during 120 minutes treatment was 20,70%, and with adding0,08 g percentage of degradation increasesd to 56,83% at the same treatment.
MENUMBUHKAN SIKAP SISWA DALAM PENCAPAIAN HASIL BELAJAR
Authors: M. Thaeb Razali
Published: July 2019

Learning is change a person's ability and can be maintained within a certain time. Various growth that occurred in the study, such as changes in behavior after someone learners got a wide range of experience in various situations of learning itself, so the variety of experiences that will lead to the changes that occur in a person learners. While the measure is to apply the measuring instrument to a particular object. Magnitudes numbers obtained, then gained significance when compared to the results of measurements with a certain standard. The attitude of a person when used in learning and teaching a subject, then there will be individuals who love a subject (positive attitude) or behave otherwise is not like a subject (a negative attitude). For those students who have a positive attitude about a subject will learn them on their own and devote his full attention on a subject matter. In contrast the attitude of learners negative about a subject. Or in other words a learner who has a positive attitude toward a subject to be loved also a subject such and by itself learners will be serious in learning.
PENGEMBANGAN LKPD BERBASIS PENDEKATAN SCIENTIFIC UNTUK MENINGKATKAN HASIL BELAJAR DAN AKTIVITAS PESERTA DIDIK PADA MATERI LARUTAN PENYANGGA
Authors: Asnaini Asnaini
Published: July 2019

This research was conducted to develop a worksheet learners (LKPD) scientific approach based on the concept of buffer solution. LKPD validated by experts and tested on students. The purpose of this study was to see the results of learning, activity and response learners. The study was conducted in SMA 11 Banda Aceh by using quantitative research methods reasearch research and development (R&D). This study used a quasi-experimental design with pre-test and post-test Group. The average score of the expert assessment of 3.28 (good). LKPD trial results showed that 95.31% of teachers and 97.5% of students responded positively to LKPD. Normality and homogeneity test results show that the data homogeneous and normal distribution. T-test results obtained tarithmetic>ttable (4.58>2.072) which means there is a significant difference in learning outcomes between the two classes. Activities learners also showed a difference in the experimental class showed better activity than the control class. Learners also give a positive response to the use of LKPD, so it can be concluded that learning by using LKPD-based scientific approaches to improve learning outcomes and learner activity.
STRATEGI PENINGKATAN KINERJA GURU YANG PROFESIONAL
Authors: Emda Amna
Published: July 2019

Education Implementation success is determined by the readiness of hearts teachers prepare their students participants through Teaching and Learning Activities . Good Quality Education For Being benchmarks of success is shown by the boarding costs . teacher. The creation of the Good boarding costs if someone has a teacher Personality And Dedication And Able to telecom - telecoms professionalism Learning hearts . Increased costs kos teacher can be done through development professionalisme.
EFEKTIVITAS PENGGUNAAN MEDIA GAMBAR DALAM PEMBELAJARAN BAHASA ARAB
Authors: Hilmi Hilmi
Published: July 2019

Learning is as an effort to change behavior in a person either changes in the level of knowledge, skills, or attitudes that deliver ones to the happiness in the world and the hereafter. In education, there are several factors that can support the implementation of the learning process, the most important factor is the availability of adequate learning media and enjoyable. Media images or photographs are pleasant enough media in Arabic learning, especially in learning Mufradat (vocabulary). By using the media, the purpose of the learning will be achieved as expected. This writing attempts to reveal the effectiveness of the media images or photographs in Arabic learning.
PENGGUNAAN MODEL PEMBELAJARAN ADVANCE ORGANIZER DALAM MENINGKATKAN HASIL BELAJAR SISWA PADA MATERI STRUKTUR ATOM
Authors: Mardhiah Ainun
Published: July 2019

This study aims to improve student learning outcomes , and knowing the students' response to the application of Advance Organizer on Atomic Structure material . Subjects in this study were students of class X SMA Negeri 11 IA3 Banda Aceh , totaling 26 people . This type of research is descriptive qualitative . To find out improving student learning outcomes used about posttest , and the questionnaire used to determine students' response to the learning model Advance Organizer . From the results obtained posttest student learning outcomes at 83.65 ; as well as the students' responses by 96.15 % who expressed delight in learning model Advance Organizer . Based on the results of this study concluded that an increase in student learning outcomes and positive student responses show the learning progress of students with learning model Advance Organizerpada use of the atomic structure of matter.
PEMBELAJARAN MODEL INQUIRI TERBIMBING PADA MATERI BESARAN DAN SATUAN UNTUK MENINGKATKAN KETERAMPILAN GENERIK SAINS DAN HASIL BELAJAR MAHASISWA
Authors: Mukhlis Mukhlis
Published: July 2019

This study aims to determine the effect of guided inquiri learning model on the quantity and unit materials to improve the KGS and student learning outcomes. This research is a quasi-experimental type / model with pretest-posttest group design using the control class. Research samples were given treatment through the model in the experimental class. The data collection activities were conducted by comparing the final test results between the experimental and control classes for KGS mathematical modeling and student learning outcomes. Data processing is done by t-test for different test. This research was conducted on Chemistry Education Program FITK UIN Ar-Raniry. The results showed that there are differences in the ability of students 'mathematical model and students' learning outcomes with guided inquiry learning model. The mean value of KGS model of experimental mathematics class is 75,20 higher than control class that is 65,53. For the value of learning result obtained experimental class equal to 73,67, higher than control class equal to 67,72. Result of t-test result of learning result known from result t arithmetic = 1,70 with dk = 64 and t table 1.67, where t count> ttabel that is 1.70> 1.67. This shows that the Ho hypothesis is rejected and Ha accepted. So that learning with guided inquiry model has an effect on the ability of KGS mathematical modeling and student learning outcomes.
METODE PENERAPAN MODEL PEMBELAJARAN PROBLEM BASED LEARNIG (PBL)
Authors: Rahmadani Rahmadani
Published: July 2019

This study aims to determine whether the application of the Problem Based Learning (PBL) learning model can improve students' critical thinking skills and student learning outcomes in the environmental pollution material in class X SMA Negeri 1 Darussalam Aceh Besar. The research was conducted in class X of SMA 1 Darusalam Aceh Besar of 20 students. This research was carried out of 2 cycles. Student learning outcomes data are obtained by giving a test (evaluation) in the form of a description of environmental pollution material. The research results were analyzed by descriptive analysis techniques and percentages. The results of observations of students' critical thinking abilities which showed an increase from cycle I to cycle II which was 59.75% in cycle I to 75.25% in cycle II. And student learning outcomes also increased from 70% in the first cycle to 85% in the second cycle. Based on the results of the research, it can be concluded that the application of Problem Based Learning (PBL) learning models can improve critical thinking skills and student learning outcomes.
Arte na educação da infância: saberes e práticas da dimensão estética
Authors: Pontes Gilvânia Maurício Dias de
Published: July 2019

O presente artigo aborda uma pesquisa que investigou a relação entre experiências estéticas e prática docente com linguagens artísticas, narradas em memoriais produzidos por professores da educação da infância. A abordagem do tema experiência estética solicitou o estabelecimento de interfaces entre aportes teóricos que envolviam diferentes campos de conhecimento, tais como filosofia, semiótica, arte/educação e pedagogia. A pesquisa teve natureza qualitativa, em que a metodologia assumiu, como princípios e estratégias de análise, a semiótica discursiva e alguns pressupostos da pesquisa (auto)biográfica, referentes à produção de narrativas como experiência de formação. O corpus da pesquisa foi composto por cinco memoriais de formação. Na análise dos textos, buscou-se identificar como as experiências estéticas dos professores estavam presentes nos discursos que teciam sobre a sua prática.
Submergir-se: incorporar espaços (in)habitáveis
Authors: Eça Teresa Torres
Published: July 2019

Este texto relata alguns projetos de investigação colaborativa nos quais se trabalhou mais a partir de conceitos do que de métodos. Partimos da questão de espaços de fronteira, entre-lugares onde a arte educação pode invocar a sua hibridez. Descrevemos estratégias da performance artística como pedagogia em espaços de construção colaborativa de aprendizagem para invocar atitudes que possam levar à provocação da visibilidade de uma arte educação comprometida com o mundo real. Falaremos de ações desenvolvidas com vários professores, em contextos de educação formal e não formal, no Brasil e em Portugal e da necessidade de trabalhar em rede e de utilizar as potencialidades que as tecnologias da comunicação oferecem.
O “pulo do gato” e a mediação em arte: possibilidades de interação
Authors: Nunes Marília Forgearini
Published: July 2019

O ser humano tem nas diferentes manifestações da linguagem uma maneira de compreender a si mesmo e o mundo que habita. As manifestações que envolvem a arte, especificamente as das artes visuais, necessitam para sua compreensão da capacidade de ver. No entanto, ver pode ser uma ação desatenta e que pouco auxilia na produção de sentido. O presente artigo destaca a importância do olhar atento para que se compreenda melhor a arte imagética. Esse olhar precisa ser mediado para que ultrapasse a desatenção que nada diz daquilo que vê e alcance a atenção produtora de sentido. Com base na narrativa do livro de imagem Pula, gato! (CASTANHA, 2008a), discutiremos a experiência com as artes visuais e explicitaremos regimes de interação (GREIMAS, 2002; LANDOWSKI, 2009;2010) que podem perpassar a experiência mediada na interação com objetos artísticos.
Apresentação
Authors: Pillar Analice Dutra , Rossi Maria Helena Wagner
Published: July 2019

Apresentação.
Trombosis venosa profunda de miembros superiores asociada a dispositivos intravasculares serie de casos
Authors: Gallmann A , Gutiérrez Magaldi I , Bertorello M , Furrer S , Lucero P
Published: July 2019

El 10% de todos los casos de trombosis venosa
profunda afectan a las extremidades superiores1
.
La trombosis venosa profunda de los miembros
superiores (TVPMS) es una entidad cada vez
más frecuente debido al uso de catéteres venosos
centrales (CVC) y de dispositivos transvenosos,
como marcapasos y cardiodesfibriladores. Las
venas más frecuentemente involucradas son la
subclavia y la axilar.
Cultural attractions of Belgrade in focus of touristic offer
Authors: Pavlovic Sanja , Vesic Marina
Published: July 2019

The study presents the touristic offer and demand for cultural attractions of
Belgrade, on the basis of the results of the questionnaire survey, i.e.,
attitudes of surveyees. The aim of the study is to establish hierarchical
order of cultural attractions of Belgrade, attributes and factors of
attractiveness, as well as of other content necessary for comprehensive
consideration of touristic offer. Program package for statistical processing
and analysys IBM Statistics 20 was used for obtaining results. Results of
the research are supposed to demonstrate whether the biggest importance
among cultural attractions of Belgrade belongs to art, ambient units, sacral
objects, the fortress, museums or events, historical, artistic, esthetic
value or authenticity, and also to indicate to the importance of factors and
the content of offer, necessary in formation of touristic product.
Myc Is Required for Adaptive β-Cell Replication in Young Mice but Is Not Sufficient in One-Year-Old Mice Fed With a High-Fat Diet
Authors: Rosselot Carolina , Kumar Anil , Lakshmipathi Jayalakshmi , Zhang Pili , Lu Geming , Katz Liora S. , Prochownik Edward V. , Stewart Andrew F. , Lambertini Luca , Scott Donald K. , Garcia-Ocaña Adolfo
Published: July 2019

Failure to expand pancreatic β-cells in response to metabolic stress leads to excessive workload resulting in β-cell dysfunction, dedifferentiation, death, and development of type 2 diabetes. In this study, we demonstrate that induction of Myc is required for increased pancreatic β-cell replication and expansion during metabolic stress–induced insulin resistance with short-term high-fat diet (HFD) in young mice. β-Cell–specific Myc knockout mice fail to expand adaptively and show impaired glucose tolerance and β-cell dysfunction. Mechanistically, PKCζ, ERK1/2, mTOR, and PP2A are key regulators of the Myc response in this setting. DNA methylation analysis shows hypomethylation of cell cycle genes that are Myc targets in islets from young mice fed with a short-term HFD. Importantly, DNA hypomethylation of Myc response elements does not occur in islets from 1-year-old mice fed with a short-term HFD, impairing both Myc recruitment to cell cycle regulatory genes and β-cell replication. We conclude that Myc is required for metabolic stress–mediated β-cell expansion in young mice, but with aging, Myc upregulation is not sufficient to induce β-cell replication by, at least partially, an epigenetically mediated resistance to Myc action.
N-PASS Versus mPAT in Assessment and Management of Neonatal Pain at Neonatal ICUs in Palestine
Authors: Elessi Khamis , Abed Shireen , Afifi Tayseer Jamal , Utt Rawan , Elblbessy Mahmood , Obaid Mohammed , Elhatal Hassan Abu , Elbhaisi Ahmed , Alsultan Khaled , Samaan Mosab , Mayadma Rawnaq , Badran Lama , Sawalha Anood , Rabaya’h Hanan , Musmar Muna , Hasassneh Juhina , Barham Aya , Shkokani Sundus , Rajabi Alaa , Nakhla Maysara , Zedan Mohammed , Abeid Mohammed
Published: July 2019

Background: Neonates frequently experience pain as a result of diagnostic or therapeutic interventions or as a result of a disease process. Neonates cannot verbalize their pain experience and depend on others to recognize, assess and manage their pain. Neonates may suffer immediate or long-term consequences of unrelieved pain. Accurate assessment of pain is essential to provide adequate management. Observational scales, which include physiological and behavioral responses to pain, are available to aid consistent pain management. Pain assessment is considered as the fifth vital sign. Objectives: Aims of the present study were (1) to compare two commonly cited neonatal pain assessment tools, Neonatal Pain, Agitation and Sedation Scale (N-PASS) and modified Pain Assessment Tool (mPAT), with regard to their psychometric qualities, (2) to explore intuitive clinicians' ratings by relating them to the tools' items and (3) to ensure that neonates receive adequate pain control. Methods: Two coders applied both pain assessment tools to 850 neonates while undergoing a painful or a stressful procedure. Each neonate was assessed before, during and after the procedure. The evaluation before and after the procedure was done using NPASS, while pain score during the procedure was assessed by mPAT. Analyses of variances and regression analyses were used to investigate whether tools could discriminate between the procedures and whether tools' items were predictors of pain severity. Results: Internal consistency, reliability and validity were high for both assessment tools. N-PASS tool discriminated between painful and stressful situations better than mPAT. There was no relation between the age of neonate and the pain score. Moreover, P-value was statistically significant between mPAT score and post procedural assessment score as well as between pre and post procedural assessment scores. Conclusion: Both assessment tools performed equally well regarding physiologic parameters. However, N-PASS makes it possible to assess pain during sedation. It was noticed that gaps exist between practitioner knowledge and attitude regarding neonatal pain.
Oral Nutritional Supplementation for the Dietary Management of Malnutrition in Cancer: Study Protocol of A Randomized, Open-Label, Multicentre Clinical Trial
Authors: Nadasi Edit , Cseh Gellert
Published: July 2019

In cancer, more than 30% of patients die due to cachexia and more than 50% of patients with cancer die with cachexia being present. Patients with cancer cachexia frequently develop a chronic negative energy and protein balance driven by a combination of reduced food intake and metabolic change. Several studies have already demonstrated the usefulness of oral nutritional supplements (ONS) in managing malnutrition of cancer patients. Though increased energy intake is very important in managing cancer-related malnutrition, the source of this extra energy and the presence of anti-inflammatory and immunonutritional components may also play an important role. Here we present the study protocol of a randomized, open-label, multicentre clinical trial aimed to determine whether an ONS composed according to the needs of patients with malignant diseases an ONS composed according to the needs of patients with malignant diseases is more effective than a general product in improving the nutritional status in cancer patients.
Relasi Ruang Publik Dan Pers Menurut Habermas
Authors: Supriadi Yadi
Published: July 2019

Jurnalisme merupakan sebuah kegiatan pengelolaan informasi yang memiliki rentang sejarah panjang berbarengan dengan perkembangan konsep ruang publik. Penelitian ini berupaya untuk mengkaji asal mula jurnalsme publik dengan menggunakan pandangan Jurgen Habermas mengenai ontologi ruang publik, sejarah pers, dan hubungan ruang publik dengan pers. Penelitian ini dilakukan dengan menggunakan studi kepustakaan yang berkaitan dengan objek penelitian. Hasil penelitian menunjukan bahwa konsep publik yang melekat pada ruang publik memiliki pengertian berbeda dalam sejarah, hingga ditemukannya konsep ruang publik yang sejalan dengan pandangan kita saat ini. Ruang publik dalam pandangan Habermas memiliki dua bentuk; ruang publik politik dan ruang publik sastra. Melalui dua konsep ruang publik tersebut peneliti menemukan kerterkaitan ruang publik dengan perkembangan pers hingga munculnya konsep jurnalisme publik.