bluuebunny/crossref_metadata_2025 huggingface dataset:
Kontaminasi Mikroplastik pada Rumput Laut dari Beberapa Lokasi Budidaya di Kabupaten Kupang, Nusa Tenggara Timur (NTT)
Authors: Serihollo Lukas Giovani Gonzales , Tangguda Sartika , Cahyanurani Annisa’ Bias , Sudiarsa I Nyoman , Pietoyo Atiek , Deo Alkuinus Fransisko Gahol , Ndoen Gilbert Ronelsto DJ
Published: February 2025

Latar belakang: Sampah plastik merupakan salah satu isu global dan masalah utama dunia saat ini. Ketika di lingkungan, sampah ini akan terpecah menjadi beberapa bagian kecil yang akan kita kenal dengan sebutan mikroplastik. Salah satu komoditas unggulan budidaya di Indonesia adalah rumput laut. Rumput laut sendiri menjadi komoditas budidaya utama di Nusa Tenggara Timur terkhususnya kabupaten kupang. Beberapa penelitian tentang pencemaran mikroplastik pada rumput laut telah dilakukan di beberapa daerah namun di provinsi Nusa Tenggara Timur (NTT) terkhususnya Kabupaten Kupang belum dilakukan.Metode: Lokasi atau stasiun pengamatan ditentukan berdasarkan pada karakteristik masing-masing lokasi atau stasiun yang berbeda. Pengambilan sampel dilakukan pada 4 titik yang merupakan desa yang melakukan budidaya rumput laut. Selanjutnya, sampel diekstraksi menggunakan 3 tahapan yakni Washed, Stirrer dan NaOH. Hasil ekstraksi kemudian diidentifikasi karakteristik (bentuk dan warna) dengan menggunakan mikroskop. Analisis data menggunakan Uji One Way ANOVA untuk membandingkan kelimpahan total pada setiap lokasi pengamatan dan membandingkan kelimpahan antar setiap bentuk.Hasil: Bentuk fiber menduduki urutan pertama dengan total partikel terbanyak yakni 51,19% MP, disusul fragmen dengan 30,56% dan film dengan 18,25%. Untuk warna yang mendominasi adalah transparan dengan 34,48%, disusul biru dengan 32,57%, kemudian hitam 9,58% dan kuning dengan 5,75%. Tidak adanya perbedaan yang signifikan untuk kelimpahan MP antara setiap lokasi pengamatan. Diduga adanya pengaruh pergerakan arus pada setiap lokasi sehingga kelimpahan masing-masing lokasi cenderung sama. Perbedaan signifikan terjadi pada setiap bentuk yang diamati. Hal tersebut diduga dipengaruhi oleh perbedaan masa jenis dari setiap bentuk MP yang mempengaruhi kelimpahannya pada rumput laut.
The eNOS Gene Polymorphism Does Not Have a Major Impact on Lipid Parameters and Premature Coronary Artery Disease in Slovene Men (Caucasians)
Authors: Milutinović Aleksandra , Hruškovičova H.
Published: February 2025

eNOS affects the NO level in the blood vessel wall, and therefore eNOS might be considered as a candidate gene for CAD. In this cross-sectional case-control association study we tested the hypothesis whether the eNOS 4a/b gene polymorphism is a genetic marker for premature CAD in Slovene men. The eNOS 4a/b gene polymorphism was tested in 403 Slovene men: 215 cases with premature CAD and 188 subjects with no history of CAD. The frequency of 4a/b genotypes did not differ between patients and controls: in CAD patients the frequencies of the 4aa, 4ab, or 4bb genotype were 5.0%, 27.9%, or 67.1%, respectively, and in controls the genotype frequencies were 5.3%, 30.9%, or 63.8%, respectively. In this study the aa genotype of the eNOS 4a/b polymorphism was not associated with premature CAD (OR = 1, 95% CI 0.4–2.3, P = 0.9). Moreover, there were no differences in lipid parameters (total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglycerides) between the subjects with the aa genotype and the subjects with the ab or bb genotype. In conclusion, we failed to demonstrate that the eNOS 4a/b gene polymorphism was a genetic marker for premature CAD in Slovene men.
Elucidating the genetic variability and diversity among Chilli (Capsicum annuum L.) genotypes for growth and yield-related traits under sodic soil in Tamil Nadu through a multivariate approach
Authors: Sidhdharth G , Vijayalatha K R , Jegadeeswari V , Ahamed S A , Padmadevi K , Parameswari K , Saravanapandian P , Meenakshisundaram P , Suresh J
Published: February 2025

Chilli (Capsicum annum L.) is a commercially important crop cultivated for both vegetable and spice uses. This study aims to explore the genetic diversity of thirty genotypes under sodic soil conditions at HC&RI(W), Tiruchirappalli, over two seasons (Kharif and Rabi) in 2023-2024. Analysis of variance (ANOVA) revealed significant variability among the genotypes for thirteen different quantitative and qualitative parameters evaluated under sodicity. The phenotypic coefficient of variation was higher than the genotypic coefficient, suggesting minimal environmental influence on the traits. Most parameters exhibited high heritability, with several (e.g., number of days for first picking, seeds per pod and chlorophyll stability index) showing high genetic advance, indicating the potential for improvement through direct selection. Principal Component Analysis (PCA) reduced the genotypes to thirteen components, with the first four accounting for 73.24% of the variability. The genotypes are divided into five clusters based on the Euclidean distance through Mahalanobsis D2 analysis grouped the genotypes into five clusters, each cluster demonstrating superiority in specific traits suitable for further breeding. Notably, the high inter-cluster distance between clusters IV & V and III & V indicates diverse genetic material that could be valuable for hybridization programs aimed at improving sodic soil tolerance.
A Curricular Study of Promoting Student Creativity and Agency through Classical Literature Classes Based on the Works of Kim Soo-young
Authors: Lee Hyeon-Jeong
Published: February 2025

This paper analyzes a real classroom curriculum using classical literature in a second-year Classical Literature classroom at a high school in Seoul, South Korea. The class was designed in a very creative way. Learners who signed up for this class could freely choose an author. Among them, Kim Soo-young (김수영) was the most voted for author. The class was organized in teams where learners participate through team activities. The teams read and interpreted Kim's poetry and prose. Each student then spoke about their favorite piece. The teams discussed their favorite pieces, then decided which work represents the team. One of the team members introduced the selected work to the other students. The students then organized a performance of the work presented with others in the class. After some discussion, Kim’s poetry, prose, and diary entries are reimagined in the form of a play. Team members share and prepare a performance of the play they have discussed. Students were able to practice as playwrights, directors, prop designers, and sound effect engineers. After this preparation, all five teams performed their plays. Using the work of Kim Soo-young, students were able to interpret literature into their own creative works. This curriculum asked students to create as well as evaluate other performances, allowing them to practice self-directed learning and develop agency over their study of classical literature. This lesson also allowed students to foster creativity through collaboration and discussion with their peers, practicing key social skills such as empathy and consideration for others.
Catechins in cancer therapy: integrating traditional and complementary approaches
Authors: Dwivedi Renu , Bala Rajni , Singh Sumitra , Sindhu Rakesh K.
Published: February 2025

Catechin is a group of bioactive flavonoids found in various plant sources such as tea, cocoa, and fruits. Recent studies have suggested that catechins has significant potential in preventing and treating cancer. Catechin exhibits a variety of biological activities that may contribute to its anticancer effects, including antioxidant, anti-inflammatory, and pro-apoptotic properties. Studies have demonstrated that catechin can inhibit cancer cell proliferation, induce cell cycle arrest, and promote apoptosis across multiple cancer types, including skin, breast, lung, liver, prostate, and colon cancers. Furthermore, catechin has shown the ability to inhibit angiogenesis, a critical process for tumor growth and metastasis, by restricting new blood vessel formation. Catechin’s impact on cancer extends beyond its direct effects on cancer cells. It modulates various signaling pathways involved in cancer progression, such as those associated with cell survival, inflammation, and metastasis. Despite these promising findings, additional research is needed to clarify the precise mechanisms of catechin’s anticancer action, optimal dosing strategies, and long-term safety in cancer prevention and treatment. This review will explore the current research landscape on tea polyphenols, particularly catechin, and their potential role in cancer prevention and therapy.
A character theoretic criterion for Fitting height
Authors: Lv Heng , Deng Yuqi , Yang Yong
Published: February 2025

For a finite group 𝐺, set

Irr
N

⁡

(
G
)

:=

{
χ
∈
Irr

(
G
)

∣
χ

(
1
)

2

∤

|
G
:
ker
χ
|

}

,

cd
N

⁡

(
G
)

:=

{

χ
⁢

(
1
)

∣

χ
∈

Irr
N

⁡

(
G
)

}

.

\begin{aligned} \operatorname{Irr}_{N}(G)&:=\{\chi\in\operatorname{Irr}(G)\mid\chi{(1)^{2}}\nmid\lvert G:\operatorname{ker}\chi\rvert\},\\
\operatorname{cd}_{N}(G)&:=\{\chi(1)\mid\chi\in\operatorname{Irr}_{N}(G)\}.\end{aligned}

In this paper, we study finite groups 𝐺 with

|

cd
N

⁡

(
G
)

|

≤
1

\lvert\operatorname{cd}_{N}(G)\rvert\leq 1

.
In particular, we prove that if 𝐺 has odd order, then

h
⁢

(
G
)

≤

|

cd
N

⁡

(
G
)

|

+
1

h(G)\leq\lvert\operatorname{cd}_{N}(G)\rvert+1

, where

h
⁢

(
G
)

h(G)

is the Fitting height of 𝐺.
EGCG inhibits ferroptosis to ameliorate APAP-induced liver injury by suppressing NEDD8 and stabilizing HUWE1 in vivo and in vitro
Authors: Ouyang Zijun , Zhang Tao , Liu Mengting , Li Fufu , Guo Hui , Li Yanhui , Chen Jieyu , Wang Feiyang , Sun Yang , Liu Dong , Sun Haiyan
Published: February 2025

Excessive consumption of acetaminophen (APAP) has emerged as the primary culprit behind drug-induced liver injury (DILI), with N-acetylcysteine serving as the principal antidote. However, use of N-acetylcysteine is limited to the early stages of APAP-induced DILI and may cause adverse side effects. Consequently, it is imperative to explore alternative therapeutic approaches to alleviate APAP-induced liver toxicity. In this study the mechanisms underlying the protective role of epigallocatechin gallate (EGCG) in DILI were determined. Our findings revealed that EGCG inhibited NEDD8, thus stabilizing HUWE1, a crucial E3 ubiquitin ligase involved in protein degradation. HUWE1 binds and degrades TFR1, a protein essential for cellular iron uptake and inhibits ferroptosis. By stabilizing HUWE1 and degrading TFR1, EGCG suppressed ferroptosis and ameliorated APAP-induced liver injury. Our results highlight the therapeutic potential of EGCG in mitigating DILI through regulation of HUWE1 and ferroptosis, which offers a promising approach for the treatment of DILI.
FARKLI GLUTENSİZ UN KARIŞIMLARIYLA HAZIRLANMIŞ HAMURLARIN DÜŞÜK (SAOS), ORTA (MAOS) VE YÜKSEK (LAOS) GENLİKLİ SALINIMLI KAYMA ÖZELLİKLERİ
Authors: Yazar Gamze
Published: February 2025

Glutensiz un karışımları (pirinç:soya unu, 8:2, w/w; karabuğday:soya unu, 8:2, w/w) ile hazırlanan hamurları yumuşak buğday unu hamuruyla reolojik bir açıdan kıyaslanarak soya unu ilavesinin glutensiz hamurların mekanik özellikleri üzerindeki etkisi küçük (SAOS), orta (MAOS) ve yüksek (LAOS) deformasyonlar altında incelenmiştir. Frekans süpürme analizleri kullanılarak pirinç-soya ve karabuğday-soya hamurlarının optimum su kaldırma kapasiteleri sırasıyla %115 ve %105 olarak bulunmuştur. Pirinç ununa soya unu ilavesiyle, SAOS deformasyonlarında azalan G ve artan tan değerleri pirinç unu hamuruna kıyasla elastikiyetin azaldığını gösterirken, karabuğday unu hamuruna soya unu ilavesi tam tersi etki yaratmıştır. MAOS deformasyonları altında elastik Lissajous-Bowditch eğrilerindeki rotasyon ve tan değerlerine göre yumuşama derecesi karabuğday-soya hamuru>buğday hamuru>pirinç-soya hamuru şeklindeyken, LAOS deformasyonları altında bu sıralama pirinç-soya hamuru>karabuğday-soya hamuru>buğday hamuru olarak belirlenmiştir. Sonuç olarak, bu çalışma glutensiz hamur formülasyonlarında yapılabilecek muhtemel değişikliklerin LAOS testleriyle analiz edilip daha gelişmiş işlenebilirlik özelliklerine sahip hamurlar ve dolayısıyla daha kaliteli glutensiz ürünler üretebilmenin mümkün olduğunu göstermiştir.
Schellingova logika TEMELJA iz 1809. godine
Authors: Nini Matthew
Published: February 2025

Schellingova ključna rasprava Spis o slobodi (Filozofska istraživanja o biti ljudske slobode i predmetima koji su s tim u vezi) iz 1809. godine odgovor je na percipirane optužbe za panteizam te je stoga i prilika za Schellinga da preispita vlastiti monizam ili „„nauk o svejedinstvu“ (All-Einheitslehre). U pokušaju da kreativno reinterpretira panteistički trop iskazan izrazom „Bog je sve stvari“, Schelling će početne stranice svoje rasprave O biti ljudske slobode posvetiti ponovnomu čitanju načela identiteta. Ovaj rad nastoji razjasniti razvoj Schellingove teorije identiteta, obraćajući posebnu pozornost na njezine najstarije izvore, posebice Platonovu teoriju o „duši svijeta“, Kantovu teleologiju i logiku Gottfrieda Ploucqueta. Tvrdit ćemo da Schelling daje jednaku važnost teoriji identiteta i revidiranoj verziji načela dovoljnoga razloga koju ćemo nazvati „načelom temelja“ (Grund). To će dovesti do ključne distinkcije u raspravi o ljudskoj slobodi iz 1809. godine, tj. do ideje da Bog ima temelj koji je u njemu, ali koji valja razlikovati od njega utoliko što postoji. Stoga reći „Bog je sve stvari“ opis je načina na koji dijelovi i cjeline međusobno djeluju u organskome sustavu, ili, točnije, kako se mikrokozmički sustavi odnose prema sveobuhvatnomu makrokozmosu kojemu pripadaju.
Neki aspekti međunarodne i domaće regulative vezane za kršenja prava djece u medijima
Authors: Šola Ivica , Homa Melita
Published: February 2025

Na temelju sadržajne analize regulativa prava djece u međunarodnom i nacionalnom kontekstu, autori daju svojevrsnu sintezu profesionalnih obilježja novinarske profesije u Republici Hrvatskoj kao temelj za daljnje istraživanje etičkih normi pri objektivnom i vjerodostojnom izvještavanju situacija, događaja i informacija u kojima su akteri djeca. Suočeni s konvencijama koje imaju gotovo višu snagu od zakona te uređuju pravo zaštite djeteta, kao i više zakona, tradicionalni i digitalni mediji nerijetko izlaze iz okvira poštivanja prava djeteta zbog senzacionalizma i profita. Profesionalna etika novinara i urednika dovodi se u pitanje značajnim brojem prijava za kršenje odredbi konvencija i zakona, što su pokazala određena empirijska istraživanja parcijalnog karaktera. Rad ujedno predstavlja temelj za daljnje istraživanje, dublju verifikaciju zaštite djece u medijima, kako u tradicionalnim tako i u svim novim medijima. Pravni i etički okvir profesionalnog novinarstva ostaje istraživačko uporište, ali s nastojanjem empirijskog utvrđivanja one „tanke linije“ koja dovodi do kršenja prava djeteta, odnosno granice koja bi pridonijela istinskom poštivanju prava djece bez obzira na težinu djela, višoj razini profesionalne i etičke odgovornosti novinara te kvaliteti medija. Medijsku pismenost onih koji danas čine medij (novinari i urednici) autori vide kao novu abecedu 21. stoljeća.
Assessment of E-Learning Facilities and Personnels for Teaching Science in Osun State Senior Secondary Schools in Nigeria
Authors: Abanikannda Mutahir Oluwafemi
Published: February 2025

The study assessed e-learning facilities and personnels for teaching science in senior schools in Osun State. The study is a descriptive study; a sample of 300 respondents from Oriade Local Government, Osogbo Local Government and Olorunda Local Government Area of Osun State formed the participants for the study. The instrument for data collections was inventory and check list and reliability level was 0.85. Data collected were analyzed using via percentage, frequency count, t-test and Person Product Moment Correction (PPMC). The findings of the study revealed that high cost of computer, fear of losing computer, monthly subscription for the internet usage, availability of some pornographic sites, underfunding from our government budgeting and irregular power supply were highest challenges encounter by science teachers in using E-learning facilities in Secondary Schools in Osun State. Study revealed that awareness campaign on the benefits of e-learning within and outside institution and employment of ICT skilled teachers are the measures to be adopted for the enhancement of the utilization of e-learning for teaching science. Hence, there is a positive and a significant relationship between e-learning utilization in teaching students and academic achievement in science. The following recommendation were made such as: employers of teachers should give sufficient technical skills to their employees on e-learning tools, ministry of education and local government education authority should provide computers, internet and other ICT tools and teachers training institutions like institutes of education, colleges of education, National Teachers Institutes and so on should make ICTs course compulsory for all the teachers under training.
The Role of Regulative Institutions in the Effects of Social, Environmental, and Economic CSR Dimensions across Nations
Authors: Zimmer Lukas , Swoboda Bernhard
Published: February 2025

Multinational corporations (MNCs) implement corporate social responsibility (CSR) initiatives in different regulative environments to attract consumers internationally. However, while CSR in general impacts consumer behavior across nations, it is unclear why and how perceptions of social, environmental, and economic CSR dimensions engage consumers in certain countries but not in other countries. The authors address this research area by referring to theoretical rationales and empirically studying the impacts of CSR dimensions on customer engagement behavior across 26 countries. They aim to contribute to our knowledge of how national institutions, especially important regulative institutions, reinforce or reduce dimensional effects, which is relevant for MNCs and public stakeholders. Using multilevel structural equation modeling, this study shows different and surprising strengths of CSR dimensions for consumer engagement and positive and negative continuous moderations of regulative institutions. The findings provide direct suggestions for MNCs and public stakeholders interested in multidimensional CSR effects across countries.
ИССЛЕДОВАНИЕ ТЕПЛОВОГО ВЗРЫВА В ПОРОШКОВОЙ СМЕСИ АЛЮМИНИЯ С НИКЕЛЕМ, ПРЕДВАРИТЕЛЬНО АКТИВИРОВАННЫМ В НИЗКОЭНЕРГЕТИЧЕСКОЙ ЛАБОРАТОРНОЙ МЕЛЬНИЦЕ
Authors: БОЯНГИН Е.Н. , ЛАПШИН О.В.
Published: February 2025

В работе изучено влияние предварительной низкоэнергетической механической активации (НМА) порошка никеля на тепловой взрыв интерметаллида Ni3Al. Рассмотрены два способа синтеза. В первом осуществлялся непрерывный нагрев смеси внешним источником энергии. Во втором при достижении заданной температуры внешний источник отключался. Показано, что НМА никеля способствует интенсификации синтеза интерметаллида Ni3Al. При непрерывном нагреве температура воспламенения не зависит от времени НМА и равна температуре плавления алюминия. При нагреве с отключением внешнего источника предварительная активация никеля снижает температуру твердофазного воспламенения. Установлено, что активация никеля в лабораторной мельнице позволяет избежать факторов его пассивации.

The effect of preliminary low-energy mechanical activation (MA) of nickel powder on the thermal explosion of the Ni3Al intermetallic compound has been studied. Two synthesis methods are considered. In the first, the mixture was continuously heated by an external energy source. In the second, when the set temperature was reached, the external source was turned off. It has been shown that low-energy MA of nickel promotes the intensification of the synthesis of the Ni3Al intermetallic compound. With continuous heating, the ignition temperature does not depend on the activation time and is equal to the melting point of aluminum. When heating with the external source turned off, preliminary activation of nickel reduces the solid-phase ignition temperature. It has been established that the activation of nickel in a laboratory mill allows one to avoid the factors of its passivation.
ДВУХУРОВНЕВЫЕ МОДЕЛИ СИНТЕЗА КОМПОЗИТОВ: ИСТОРИЯ И ВОЗМОЖНОСТИ
Authors: КНЯЗЕВА А Г.
Published: February 2025

Существуют разнообразные способы синтеза композитов из смесей порошков металлов, формирующих интерметаллидные фазы, а также из смесей порошков металлов и неметаллов (например, углерода или бора). В 70-е годы прошлого столетия был предложен подход к описанию процессов горения и взрыва с выделением реакционных ячеек, который с современных позиций можно отнести к двухуровневым моделям синтеза. Подход активно развивался для бинарных систем, однако так и остался достаточно условным. В настоящей работе представлен обзор подобных моделей; предложено их развитие за счет учета сопутствующих процессов (не только диффузии, но и эволюции напряженно-деформированного состояния) и модификации применительно к синтезу, управляемому лазерным или электронным лучом.

There are various methods for synthesizing composites from mixtures of powders of metals forming intermetallic phases, as well as from mixtures of powders of metals and non-metals (for example, carbon or boron). In the 1970s, an approach was proposed to describe combustion and explosion processes with identification of reaction cells, which from modern positions can be classified with two-level synthesis models. The approach has been actively developed for binary systems, but remained rather conditional. This paper presents an overview of similar models; it is suggested that they can be developed by taking into account accompanying processes (not only diffusion, but also the evolution of the stress-strain state), and modified in relation to synthesis controlled by a laser or electron beam.
СИНТЕЗ ОКСИНИТРИДНЫХ КОМПОЗИТОВ ПРИ ГОРЕНИИ СМЕСИ ФЕРРОСИЛИЦИЙ‒ПРИРОДНЫЙ МИНЕРАЛ‒АЛЮМИНИЙ В АЗОТЕ
Authors: КРЮКОВА О.Г. , НЕВМЫВАКА А.А. , АКУЛИНКИН А.А. , ТАТАРИНОВА Т.В.
Published: February 2025

Реализован направленный синтез оксинитридных композитов путем организации сопряженных процессов. В качестве основного (индуцирующего) процесса рассматривается взаимодействие ферросилиция в азоте в режиме горения. Фазовый состав продуктов сопряженных процессов определяется химическим и фазовым составом компонентов, добавляемых к ферросилицию перед проведением самораспространяющегося высокотемпературного синтеза. Установлено влияние основных параметров синтеза на скорость горения, содержание азота, фазовый состав и морфологию продуктов синтеза. Показана химическая стадийность взаимодействия ферросилиция с добавками природных минералов (циркон, ильменит, шунгит) и алюминия в атмосфере азота. Фазовый состав продуктов определяется химическими превращениями, происходящими в волне горения. Установлено, что введение алюминия способствует снижению либо устранению фазы Si2N2O в продуктах синтеза по мере его увеличения и получению композитов на основе твердого раствора Si3N4 (SiAlON). Микроструктура продуктов горения представлена сростками (5‒10 мкм) мелких ограненных кристаллов, бесформенными образованиями и пластинчатыми кристаллами. Получены оксинитридные композиты с открытой пористостью 51,0‒68,8 %.

Targeted synthesis of oxynitride composites is implemented by means of organizing coupled processes. Interaction of ferrosilicon with nitrogen in the combustion regime is considered as the main (inducing) process. The phase composition of the products of the coupled processes is determined by the chemical and phase compositions of the components added to ferrosilicon before performing self-propagating high-temperature synthesis. The influence of the basic products of the synthesis on the burning rate, fraction of nitrogen, phase composition, and morphology of synthesis products is considered. Chemical stages of ferrosilicon interaction with additives of natural minerals (zircon, ilmenite, and shungite) and aluminum in a nitrogen medium are demonstrated. The phase composition is determined by chemical transformations in the combustion wave. It is found that addition of aluminum leads to reduction or elimination of the Si2N2O phase in synthesis products with an increase in the aluminum fraction and obtaining composites based on the Si3N4 (SiAlON) solid solution. The microstructure of combustion products is presented by aggregates (5–10 μm) composed of small faceted crystals, shapeless structures, and crystal flakes. Oxynitride composites with an open porosity value of 51.0–68.8% are obtained.
„Kunszt pisania” jako wartość w dysertacji z 1788 roku, ogłoszonej przez Jacka Idziego Przybylskiego, bibliotekarza Szkoły Głównej Koronnej w Krakowie
Authors: Kuryan Inesa
Published: February 2025

We rarely consider whether the alphabet holds value for us. It is more of a tool for everyday writing, which value is variable and has its own history. The most precious aspect is that the act of writing with letters inherently contains the condition of commemorating only important content for future generations. An inspiring text from 1788 on the development of the Art of Writing among the Ancients by Jacek Idzi Przybylski (1756–1819), a well-known Polish figure of the Enlightenment, translator, and university librarian in Kraków, allows us to view texts and accumulated knowledge, for which universities ultimately bore responsibility, from both diachronic and axiological perspectives. This is crucial for understanding the university as a foundation for future generations of students, scholars, creators, and, more broadly, citizens.
The author speaks about texts through the example of classical philology and its ethical values, reflecting on how writing and texts developed with an emphasis on particular skills in thinking and expressing emotions. For a long time, these skills were singled out as the only ones worthy of being recorded, commemorated, and passed on to future generations in the development of human civilization. The earliest attempts to record events using alphabetic writing were, for centuries, linked to valuable messages, maturing into outstanding content in both painting and literature. The axiology of the earliest ancient texts – based on high poetic standards – shaped the translation work of Jacek Idzi Przybylski,, a somewhat forgotten scholar and translator of the late 18th and early 19th centuries. He, in turn, enabled students at the University of Vilna in the early 19th century to develop their own talents through his works and, as a result, demonstrate true “art of writing” in the form of outstanding works of Vilnian Romanticism.
ІННОВАЦІЙНО-ПРОМИСЛОВИЙ РОЗВИТОК РЕГІОНІВ УКРАЇНИ: ПЕРСПЕКТИВИ ТА ОБМЕЖЕННЯ
Authors: ЧОРНИЙ Роман , ВЕНГЕР Віталій , КУШНІРЕНКО Оксана , ЧОРНА Неля
Published: February 2025

Війна в Україні негативно вплинула на інноваційно-індустріальний розвиток регіонів і загострила системні проблеми технологічного відставання підприємств. Це вимагає розробки і впровадження ефективних інструментів регіональної політики інноваційно-промислового розвитку на основі обґрунтованої науково-аналітичної бази, що і є метою дослідження. Комплексна оцінка позиціонування регіонів України з використанням відповідних індикаторів дозволила виявити ключові обмеження інноваційно-промислового розвитку регіонів, які призводять до збільшення розриву між центром та іншими регіонами.
На основі методик державних стратегічних документів визначено показники, які впливали на стан інноваційно-промислового розвитку регіонів, а саме: економічна ефективність, інвестиційно-інноваційний розвиток, фінансова самодостатність, ефективність ринку праці, зовнішньоекономічна діяльність, екологічний стан тощо.
Показано, що завдяки релокації промислових підприємств відбулися диверсифікація виробничо-господарської діяльності, зміна організаційної та підприємницької культури через поєднання досвіду, управлінських навичок, швидкості ухвалення рішень, що в цілому позитивно відобразилося на розвитку бізнес-середовища і стимулюванні конкуренції у регіонах.
Узагальнено кращі практики зарубіжного досвіду щодо розвитку індустріальних парків як практичного інструменту промислової політики для формування сприятливого середовища інноваційно-промислового розвитку регіонів шляхом удосконалення регулюючих норм законодавства щодо розширення переліку видів діяльності учасників індустріального парку; закріплення поняття «екоіндустріальний парк»; урегулювання правил розміщення в межах індустріального парку крім промислових інших об’єктів; урегулювання переходу права власності на землю від ініціатора індустріального парку до іншої юридичної особи; удосконалення процедури включення і виключення з Реєстру індустріальних парків України тощо.
Обґрунтовано інструменти ефективної державної підтримки інноваційно-промислового розвитку шляхом створення сприятливого середовища для дифузії інновацій і підтримки регіональних виробників, що сприятиме вирішенню проблеми зовнішнього руху українського бізнесу в інтересах національного економічного зростання і зміцнення обороноздатності України.
RATIONALIZING PUBLIC SPENDING ACCORDING TO THE REQUIREMENTS OF HUMAN SECURITY OBJECTIVES: A COMPARATIVE STUDY USING DATA ENVELOPMENT ANALYSIS
Authors: BENLEBBAD Mohammed , BOUDJOURFA Benasser
Published: February 2025

Public expenditures are a fundamental tool for governments to shape their economies. Traditionally, they were primarily used to intervene in markets and address public needs. However, in recent years, they have evolved to become essential for achieving broader goals, particularly those related to human security. This security encompasses social, health, environmental, and economic well-being, and is crucial for fostering sustainable development.
To assess the efficiency of public expenditures in promoting human security, we conducted a study using data envelopment analysis (DEA). DEA is a mathematical technique that compares the relative efficiency of different decision-making units (DMUs) by measuring their output-to-input ratios. We analyzed 44 countries with varying geographic locations and income levels, examining their input efficiency under different assumptions about returns to scale.
Our findings revealed that 36% of the countries in our sample were operating at full efficiency, and the average efficiency was impressively high at 78%. Countries like India and Vietnam served as models for over 17 other countries. Furthermore, we identified specific actions that could be taken to improve efficiency. For example, Greece, Poland, and Hungary could potentially reduce public spending by 49%, 12%, and 51% respectively without compromising human security. Additionally, our findings highlight the need to reevaluate our understanding of human security. We must shift away from the notion that it primarily involves consumer spending and toward a perspective that emphasizes investment in societal well-being. Such investments create the necessary conditions for individuals to engage in economic activities effectively.
REVIEW of the monograph "Myocardial preconditioning: new approaches and molecular mechanisms", ed. A.G. Portnichenko (Kyiv, 2019. - 271 p.)
Authors:   Bogomoletz Institute of physiology NAS of Ukraine, Kyiv, Ukraine, Sagach. V.F.
Published: February 2025

Despite the intensification of scientific, clinical and social programs aimed at limiting cardiovascular disease prevalence and reducing mortality, this problem is currently extremely unsolved.
REVIEW of the monograph KV Rozova "Structurally-mediated mitochondrial response to hypoxia and neurodegeneration" (Kyiv: Knowledge of Ukraine, 2019. - 163 pp. ISBN 978-966-316-455-7)
Authors:   Bogomoletz Institute of physiology NAS of Ukraine, Kyiv, Ukraine, Skibo G.G.
Published: February 2025

The presented monograph is devoted to the experimental study of the mechanisms responsible for changes in the morphofunctional state of mitochondria in lung tissue and myocardium (and in neurodegeneration and the tissues of brain structures) in the case of secondary tissue hypoxia.
Patient-specific Predictors of Haemolysis with Percutaneous Ventricular Assist Devices
Authors: Sullivan Alexander E , Granger Hannah , Dupuis Leonie , Napper Jonathan , Tran Lena , Laws J Lukas , Wells Quinn S , Farber-Eger Eric , Alvis Bret D , O’Leary Jared M , Bommareddi Swaroop , Amancherla Kaushik V , Rali Aniket S
Published: February 2025

Introduction: Percutaneous ventricular assist devices (pVADs) are increasingly used in cardiogenic shock but are associated with complications including haemolysis. The aim of this study was to investigate patient characteristics associated with haemolysis in cardiogenic shock patient population. Methods: Consecutive patients were identified using Current Procedural Terminology (CPT) codes for pVAD insertion. Patient characteristics, laboratory and imaging data, and patient outcomes were abstracted manually and using validated automated methods. Laboratory-defined haemolysis required a drop in haemoglobin ≥2 mg/dl with either lactate dehydrogenase ≥250 units/l or undetectable haptoglobin. Clinically significant haemolysis was defined as laboratory-defined haemolysis necessitating transfusion. Primary outcome was the association between haemolysis and on-device and 30-day mortality. Results: A total of 196 patients underwent pVAD insertion for cardiogenic shock during the study period and were included. Laboratory-defined haemolysis occurred in 46 patients (23.5%), of whom 12 (6.1%) had clinically significant haemolysis. Haemolysis occurred more often following emergency insertion, rather than elective insertion (84.8% versus 40.0%, p<0.001) in patients with elevated lactic acid levels (median 2.5 versus 1.6, p=0.016) and elevated heart rates (92.5 BPM versus 86.5 BPM, p=0.023). After multivariable adjustment, there was no association between laboratory-defined haemolysis and on-device (OR 0.6; 95% CI [0.1–3.4]; p=0.565) or 30-day mortality (OR 2.1; 95% CI [0.4–13.0]; p=0.391). Conclusion: Laboratory-defined haemolysis was common in patients with cardiogenic shock and pVAD, but clinically significant haemolysis was not. There was no association between haemolysis and on-device or 30-day mortality.
Associations of Obesity and Prognostic Nutritional Index on 1-Year Mortality in Patients with Acute Heart Failure
Authors: El-Sheikh Mohammed , Olsen El Caidi Nora , Kandiah Aginsha , Tonning Sandra Henriette , Taraldsen Ida Arentz , Wisborg Frederik Dencker , Andersen Ove , Hove Jens Dahlgaard , Grand Johannes
Published: February 2025

Background: Increased BMI is paradoxically associated with improved survival among patients with acute heart failure (AHF). However, the impact of different nutritional status on this obesity paradox on 1-year mortality is underreported. The prognostic nutritional index is a simple tool to assess nutrition status. Methods: From 10,027 emergency department admissions at the Amager and Hvidovre Hospital, Copenhagen University Hospital in Denmark, all patients with AHF were identified. Patients were categorised by BMI (normal: 18.5–24.9 kg/m², overweight: 25–29.9 kg/m², obese: ≥30 kg/m²) and nutritional status using the prognostic nutritional index (malnourished: <38, well-nourished: ≥38). Kaplan–Meier curves analysed cumulative survival, and Cox regression examined associations between BMI, nutritional status and outcomes, expressed as HR and 95% CI. Results: Among 383 AHF patients (median age 76 years), 41.3% were malnourished and 58.7% well nourished. In the well-nourished group, obesity was inversely associated with 1-year mortality (adjusted HR 0.48; 95% CI [0.24–0.95]; p=0.035). However, this correlation disappeared in the malnourished group (adjusted HR 1.08; 95% CI [0.59–2.00]; p=0.798). Mortality rates were significantly lower in the well-nourished group among patients with overweight and obesity. Conclusion: Obesity was associated with reduced 1-year mortality only in AHF patients with good nutritional status, while in malnourished patients, obesity was not associated with 1-year mortality. The prognosis in patients with AHF depends on both the presence of obesity and their nutritional status, highlighting the need for nutritional assessment for risk stratification.
КОНЦЕНТРАЦІЯ НАПРУЖЕНЬ В БІМАТЕРІАЛЬНИХ ПЛАСТИНАХ З ТРИКУТНИМ ОТВОРОМ
Authors: Гарт Е. Л. , Сясєва А. А.
Published: February 2025

Проведено комп’ютерне моделювання напружено-деформованого станукусково-однорідних біматеріальних пластин з малим трикутним отвором за різної ширини центральної вставки з іншого матеріалу. На основі здійсненого скінченноелементного аналізу визначено вплив геометричних параметрів і механічних характеристик матеріалу вставки на концентрацію напружень в околі отвору. Подано рекомендації щодо шляхів зменшення величини коефіцієнта концентрації напружень
ВПЛИВ ПАРАМЕТРІВ СИМЕТРИЧНО РОЗТАШОВАНИХ ЕЛІПТИЧНИХ ВКЛЮЧЕНЬ НА КОНЦЕНТРАЦІЮ НАПРУЖЕНЬ НАВКОЛО КРУГОВОГО ОТВОРУ В ЦИЛІНДРИЧНІЙ ОБОЛОНЦІ
Authors: Гарт Е. Л. , Шебанов О. Д.
Published: February 2025

Здійснено числове дослідження напружено-деформованого стану тонкостінної циліндричної оболонки з малим круговим отвором, оточеним двома або чотирма симетрично розташованими еліптичними включеннями з іншого матеріалу. Визначено вплив механічних властивостей включень, їх кількості, способу розташування та відстані між ними й отвором на концентрацію напружень в оболонці при застосуванні методу скінченних елементів. Виявлено механічні ефекти як результат впливу включень
ПРОСТОРОВА ЗАДАЧА СТІЙКОСТІ КОМПОЗИТНОГО МАТЕРІАЛУ, АРМОВАНОГО ДВОМА ПОСЛІДОВНО РОЗМІЩЕНИМИ ВОЛОКНАМИ
Authors: Декрет В. А. , Зеленський В С.. , Бистров В. М.
Published: February 2025

Із застосуванням числових методів побудовано розрахункову модель для дослідження втрати стійкості композитного матеріалу, армованого двома сусідніми послідовно розміщеними волокнами. З’ясовано залежність форм втрати стійкості від відстані між волокнами. Проведено порівняльний аналіз одержаних результатів з даними для моделі ”коротких волокон” для плоскої задачі
ІНДИВІДУАЛЬНЕ ПРОЄКТУВАННЯ КАРДІОСТЕНТІВ З ФУНКЦІОНАЛЬНО-ГРАДІЄНТНИМИ МОСТАМИ МІЖ ГОФРОВАНИМИ КІЛЬЦЯМИ
Authors: Дісковський О. А. , Синиціна Ю. П. , Рижков Е. В. , Прокопов С. О.
Published: February 2025

Вигин кардіостента, що складається з гофрованих кілець, з'єднаних «мостами», моделюється як вигин балки з пружними вставками. Пропонується механізм адаптації стента до специфічного для пацієнта прогину артерії за допомогою мостів, згинальна жорсткість яких залежить від місця їх розташування. Показано, що застосування таких мостів призводить до зменшення напружень взаємодії між стентом та судинною стінкою і, як наслідок, зменшує згинальне травмування судини під час стентування
НЕСТАЦІОНАРНА РЕАКЦІЯ ТРЬОХШАРОВОЇ ПЛАСТИНИ З В’ЯЗКОПРУЖНИМ ЗАПОВНЮВАЧЕМ НА ДІЮ РУХОМОГО НОРМАЛЬНОГО НАВАНТАЖЕННЯ
Authors: Пожуєв А. В. , Пожуєв В. І.
Published: February 2025

Показана можливість розповсюдження принципу відповідності пружної і в’язкопружної задач на динамічні задачі в нестаціонарній постановці при розрахунку трьохшарових пластин з м’яким в’язкопружним заповнювачем. При цьому звернута увага на те, що сумісні застосування інтегральних перетворень Фур’є і Лапласа із застосуванням для отримання оригіналів шуканих величин спеціального числового алгоритму дозволяє за однією схемою розглянути випадки, коли залежність між компонентами в’язкопружного матеріалу задається як в диференціальній, так і в інтегральній формі. Проаналізовано вплив швидкості руху навантаження вздовж несучих шарів пластини на її напружено-деформований стан і проведено порівняння з випадком, коли матеріал заповнювача вважається пружним
ОСЕСИМЕТРИЧНА КОНТАКТНА ЗАДАЧА ДЛЯ ПРОСТОРУ ЗІ СФЕРИЧНОЮ ПОРОЖНИНОЮ
Authors: Соляр Т. Я. , Соляр О. І.
Published: February 2025

Наведено числовий алгоритм розв’язування задачі про сферичну порожнину в просторі, в яку втискається жорсткий штамп осесиметричної форми. Під дією штампа контакт відбувається на окремих, наперед невідомих ділянках контакту. Контактну задачу сформульовано у вигляді інтегральних рівнянь-нерівностей Сіньоріні, які, використовуючи квадратурні формули для сингулярних інтегралів, трансформовано до системи лінійних алгебричних рівнянь-нерівностей. Розв’язування системи зведено до знаходження мінімуму квадратичної форми за лінійних обмежень на невідомі контактні напруження. З використанням розробленого алгоритму досліджено задачу про втискання осесиметричного жорсткого витягнутого та сплюснутого сфероїдальних штампів у пружний простір зі сферичною порожниною
МЕТОД РОЗВ’ЯЗАННЯ НЕСТАЦІОНАРНИХ ЗАДАЧ ТЕОРІЇ ТЕРМОПЛАСТИЧНОСТІ ДЛЯ ПЛАСТИН ТА ОБОЛОНОК
Authors: Стеблянко П. О.
Published: February 2025

Існуючі дослідження в галузі теорії пластин та оболонок можна виокремити у два напрями: перший напрям – комбіновані аналітичні та напіваналітичні методи, які ґрунтуються на континуальній моделі розрахунку, та другий напрям, який базується на дискретному поданні розрахункової моделі, з метою використання добре відомих числових методів. Обидва напрями мають в своєму арсеналі потужні програмні комплекси, проте при практичній реалізації існуючих методів для складних оболонкових конструкцій виникає потреба  покращувати отримані результати. Одна з можливостей базується на ідеї кардинального підвищення точності обчислень.
A RIGID BEAM ACTING IN THE SHEARING MANNER TO THE QUASI-CRYSTALLINE HALF-SPACE
Authors: Алтумаймі M. , Лобода В. В.
Published: February 2025

An analytical model describing the action a rigid beam under shear forces to the quasi-crystalline half-space is analyzed. The elasticity theory of quasicrystals and the method of complex variables is used. Graphs of stresses and displacements for both phonon and phason fields along the edge of the half-space have been obtained
THE EFFICIENT METHOD OF THE TIME TO CORROSION FRACTURE OF METALS ON DETERMINING
Authors: Мамедова Х. А.
Published: February 2025

The efficient method for the time to corrosion fracture of metals was suggested depending on joint or taken separately action of strain, temperature, connection and potential at the unknown low of their variation from time in corrosion process.
La constitución de servidumbres de paso mediante convenio tácito en Costa Rica
Authors: García Murillo José Daniel
Published: February 2025

El presente escrito aborda un análisis de la posibilidad de constituir servidumbres de paso mediante convenio tácito. Se analiza el convenio como una fuente de derecho de suma relevancia (...)
Effects of Portfolio Assessment Technique on Senior Secondary School Students’ Achievement in Economics in Pankshin, Plateau State, Nigeria
Authors:   Department of Educational Foundations, Federal College of Education, Pankshin, Idakwoji Solomon , Wakjissa Sayita G. ,   Department of Educational Foundations, Faculty of Education, University of Jos, Dadughun Saurayi I. ,   Department of Educational Foundations, Faculty of Education, University of Jos
Published: February 2025

The study focuses on effects of portfolio assessment technique on senior secondary school students’ achievement in economics in Pankshin, Plateau State, Nigeria. Three purpose of the study was formulated alongside research questions and hypotheses. The study adopted the quasi-experimental research design. The population of the study consisted of all the Senior Secondary Two (SSII) students offering economics in public and private secondary schools within Pankshin metropolis of Plateau State. There were eight public and eight private secondary schools in Pankshin metropolis giving a total of 16 secondary schools that met the criteria with a population of 546 students that offer economics, made up of 237 boys and 307 girls. The sample of the study is four senior secondary schools comprising of two public and two private schools out of the 16 senior secondary schools within the area of the study. The schools were assigned to the experimental and control groups. One public and one private secondary school is assigned to experimental group and the other public and private school is assigned to control group. The study adopted proportionate stratified sampling technique in selecting the sample for the study. Two instruments are used for the study. The instruments used are the Economic Achievement Test (EAT) and the Economic Attitude Questionnaire (EAQ). The study adopted both descriptive and inferential statistics for the study. The descriptive statistics of frequency distribution tables, simple percentages, means and standard deviation were used for answering the research questions, while the Analysis of Covariance (ANCOVA) was used for testing the hypotheses formulated for the study at 0.05 level of significance. The result of the finding revealed that in the experimental group, the post-test achievement mean score was 62.740 and standard deviation of 11.906, higher than the pre-test mean score of 29.364 and standard deviation of 11.031 with a mean gain of 33.376., indicating that there was improvement in the achievement of students in Economics after treatment. The study recommend that Government should be proper care-giving support to learners on the area of their interest. Students motivation should be adequately to enhance the level of skills in them
Estimating Tax Buoyancy for Nigeria in the light of Emerging Tax Reforms
Authors:   Central Bank of Nigeria, Abuja, Nigeria, Udeaja Elias A. , Yusuf Mariam ,   Central Bank of Nigeria, Abuja, Nigeria, Offum Peter F. ,   Central Bank of Nigeria, Abuja, Nigeria
Published: February 2025

The need to improve tax revenue amidst rising expenditure and debt levels has necessitated a plethora of tax reforms in Nigeria. Such reforms are usually tailored to enhance tax revenue by widening the tax net and promoting efficiency in tax administration. However, it is unclear whether there is dynamic tax buoyancy in Nigeria in the light of emerging tax reforms. Tax buoyancy provides valuable insights about the role of a country’s tax system in macroeconomic stabilisation and fiscal sustainability. This study, therefore, estimates the dynamic tax buoyancy for Nigeria, using data for the period spanning 2010Q1 to 2023Q4, through the mechanism of an error correction model. The buoyancy indicates whether collectability of the tax on income, profit, and consumption increases. We estimate a baseline error correction model before controlling for the contraction and expansion phases of the business cycle, discretionary tax policy changes and inflation. The baseline result indicate tax buoyancy estimates of less than one both in the short-run and long-run, with that of the short-run closer to one. Considering the phases of the business cycles, the buoyancy estimates were not statistically significant as in the case of controlling for discretionary tax policy changes. Finally, accounting for the role of inflation yielded a buoyancy estimate less than one, suggesting absence of short-run and long-run buoyancy. These findings highlight the inefficiencies in the Nigerian tax system, where tax revenues do not grow in tandem with output and discretionary tax policy changes. The paper, therefore, recommends the need for policy to focus on the maximization of tax revenue by plugging leakages through the intensification of the use of technology in tax administration.