bluuebunny/crossref_metadata_2025 huggingface dataset:
Natural infection of Neotropical bats with hantavirus in Brazil
Authors: Sabino-Santos Jr Gilberto , Maia Felipe Gonçalves Motta , Martins Ronaldo Bragança , Gagliardi Talita Bianca , Souza William Marciel de , Muylaert Renata Lara , Luna Luciano Kleber de Souza , Melo Danilo Machado , Cardoso Ricardo de Souza , Barbosa Natalia da Silva , Pontelli Marjorie Cornejo , Mamani-Zapana Priscila Rosse , Vieira Thallyta Maria , Melo Norma Maria , Jonsson Colleen B. , Goodin Douglas , Salazar-Bravo Jorge , daSilva Luis Lamberti Pinto , Arruda Eurico , Figueiredo Luiz Tadeu Moraes
Published: June 2018

Bats (Order: Chiroptera) harbor a high diversity of emerging pathogens presumably because their ability to fly and social behavior favor the maintenance, evolution, and dissemination of these pathogens. Until 2012, there was only one report of the presence of Hantavirus in bats. Historically, it was thought that these viruses were harbored primarily by rodent and insectivore small mammals. Recently, new species of hantaviruses have been identified in bats from Africa and Asia continents expanding the potential reservoirs and range of these viruses. To assess the potential of Neotropical bats as hosts for hantaviruses and its transmission dynamics in nature, we tested 53 bats for active hantaviral infection from specimens collected in Southeastern Brazil. Part of the hantaviral S segment was amplified from the frugivorous Carollia perspicillata and the common vampire bat Desmodus rotundus. DNA sequencing showed high similarity with the genome of Araraquara orthohantavirus (ARQV), which belongs to one of the more lethal hantavirus clades (Andesorthohantavirus). ARQV-like infection was detected in the blood, urine, and organs of D. rotundus. Therefore, we describe a systemic infection in Neotropical bats by a human pathogenic Hantavirus. We also propose here a schematic transmission dynamics of hantavirus in the study region. Our results give insights to new, under-appreciated questions that need to be addressed in future studies to clarify hantavirus transmission in nature and avoid hantavirus outbreaks.
Clinical features, fungal load, coinfections, histological skin changes, and itraconazole treatment response of cats with sporotrichosis caused by Sporothrix brasiliensis
Authors: de Souza Elaine Waite , Borba Cintia de Moraes , Pereira Sandro Antonio , Gremião Isabella Dib Ferreira , Langohr Ingeborg Maria , Oliveira Manoel Marques Evangelista , de Oliveira Raquel de Vasconcellos Carvalhaes , da Cunha Camila Rocha , Zancopé-Oliveira Rosely Maria , de Miranda Luisa Helena Monteiro , Menezes Rodrigo Caldas
Published: June 2018

Zoonotic sporotrichosis caused by the fungus Sporothrix brasiliensis is usually severe in cats. This study investigated the associations between clinical features, fungal load, coinfections, histological skin changes, and response to itraconazole in cats with sporotrichosis caused by S. brasiliensis. Fifty-two cats with skin lesions and a definitive diagnosis of sporotrichosis were treated with itraconazole for a maximum period of 36 weeks. The animals were submitted to clinical examination and two subsequent collections of samples from the same skin lesion for fungal diagnosis and histopathology, as well as serology for feline immunodeficiency (FIV) and leukaemia (FeLV) viruses. Thirty-seven (71%) cats were clinically cured. Nasal mucosa lesions and respiratory signs were associated with treatment failure. Cats coinfected with FIV/FeLV (n = 12) had a lower neutrophil count in the lesion. A high fungal load in skin lesions was linked to young age and treatment failure, as well as to a longer time of wound healing, poorly formed granulomas and fewer neutrophils, macrophages and lymphocytes in these lesions. These results indicate that itraconazole is effective, but nasal mucosal involvement, respiratory signs and high fungal loads in skin lesions are predictors of treatment failure that will assist in the development of better treatment protocols for cats.
Rhizobium tumorigenes sp. nov., a novel plant tumorigenic bacterium isolated from cane gall tumors on thornless blackberry
Authors: Kuzmanović Nemanja , Smalla Kornelia , Gronow Sabine , Puławska Joanna
Published: June 2018

Four plant tumorigenic strains 932, 1019, 1078T and 1081 isolated from cane gall tumors on thornless blackberry (Rubus sp.) were characterized. They shared low sequence identity with related Rhizobium spp. based on comparisons of 16S rRNA gene (≤98%) and housekeeping genes atpD, recA and rpoB (<90%). Phylogenetic analysis indicated that the strains studied represent a novel species within the genus Rhizobium, with Rhizobium tubonense CCBAU 85046T as their closest relative. Furthermore, obtained average nucleotide identity (ANI) and in silico DNA–DNA hybridization (DDH) values calculated for whole-genome sequences of strain 1078T and related Rhizobium spp. confirmed the authenticity of the novel species. The ANI-Blast (ANIb), ANI-MUMmer (ANIm) and in silico DDH values between strain 1078T and most closely related R. tubonense CCBAU 85046T were 76.17%, 84.11% and 21.3%, respectively. The novel species can be distinguished from R. tubonense based on phenotypic and chemotaxonomic properties. Here, we demonstrated that four strains studied represent a novel species of the genus Rhizobium, for which the name Rhizobium tumorigenes sp. nov. is proposed (type strain 1078T = DSM 104880T = CFBP 8567T). R. tumorigenes is a new plant tumorigenic species carrying the tumor-inducing (Ti) plasmid.
Controllable synthesis of cellulose benzoates for understanding of chiral recognition mechanism and fabrication of highly efficient chiral stationary phases
Authors: Chang Limin , Zhang Jinming , Chen Weiwei , Zhang Mei , Yin Chunchun , Tian Weiguo , Luo Zhu , Liu Weili , He Jiasong , Zhang Jun
Published: June 2018

The core of enantioseparation is to combine the hydrophobic helical conformation of cellulose derivatives with weak non-enantioselective interactions.
Decreasing the uncertainty of peak assignments for the analysis of synthetic cathinones using multi-dimensional ultra-high performance liquid chromatography
Authors: Ochoa Cecilia M. , Shoenmakers Peter , Mallet Claude R. , Lurie Ira S.
Published: June 2018

Peak assignment uncertainty using retention time is significantly reduced by the use of multi-dimensional ultra-high performance liquid chromatography.
A surface graft polymerization process on chemically stable medical ePTFE for suppressing platelet adhesion and activation
Authors: Liu Yihua , Munisso Maria Chiara , Mahara Atsushi , Kambe Yusuke , Fukazawa Kyoko , Ishihara Kazuhiko , Yamaoka Tetsuji
Published: June 2018

An effective grafting method for modifying chemically inert and elaborately porous medical expanded-polytetrafluoroethylene (ePTFE).
Polymorphism and properties of ammonium scandium sulfate (NH4)3Sc(SO4)3: new intermediate compound in scandium production
Authors: Pasechnik L. A. , Tyutyunnik A. P. , Enyashin A. N. , Samigulina R. F. , Ilyina E. A. , Skachkov V. M. , Medyankina I. S. , Yatsenko S. P.
Published: June 2018

Discovery of (NH4)3Sc(SO4)3 polymorphs and comprehensive characterization of their structural and thermal properties that can promote extraction and production of scandium.
Correction: Ab initio calculation of energy levels of trivalent lanthanide ions
Authors: Freidzon Alexandra Ya. , Kurbatov Ilia A. , Vovna Vitaliy I.
Published: June 2018

Correction for ‘Ab initio calculation of energy levels of trivalent lanthanide ions’ by Alexandra Ya. Freidzon et al., Phys. Chem. Chem. Phys., 2018, 20, 14564–14577.
Electrocatalytic valorisation of biomass derived chemicals
Authors: Du Lei , Shao Yuyan , Sun Junming , Yin Geping , Du Chunyu , Wang Yong
Published: June 2018

Recent progress in electro-valorization of biomass-derived intermediates is reviewed, while a perspective on future R&D in this field is provided.
The unsuspected influence of the pyridyl-triazole ligand isomerism upon the electronic properties of tricarbonyl rhenium complexes: an experimental and theoretical insight
Authors: Wang Jinhui , Delavaux-Nicot Béatrice , Wolff Mariusz , Mallet-Ladeira Sonia , Métivier Rémi , Benoist Eric , Fery-Forgues Suzanne
Published: June 2018

How can the intimate nature of the triazole moiety govern the geometry and luminescence properties of a rhenium complex?
Electrochemical water oxidation using a copper complex
Authors: Nestke Sebastian , Ronge Emanuel , Siewert Inke
Published: June 2018

This study highlights the importance of proton coupled electron transfer (PCET) during electrochemical-driven water oxidation catalysis employing a copper complex.
Bimetallic cooperative effect on O–O bond formation: copper polypyridyl complexes as water oxidation catalyst
Authors: Su Xiao-Jun , Zheng Chu , Hu Qin-Qin , Du Hao-Yi , Liao Rong-Zhen , Zhang Ming-Tian
Published: June 2018

Two is better than one. The bimetallic cooperation in a binuclear copper complex, compared with the corresponding mononuclear catalyst, can decrease the catalytic overpotential and improve the catalytic efficiency.
Hydrogenation of titanocene and zirconocene bis(trimethylsilyl)acetylene complexes
Authors: Pinkas Jiří , Gyepes Róbert , Císařová Ivana , Kubišta Jiří , Horáček Michal , Žilková Naděžda , Mach Karel
Published: June 2018

Different metal electropositivity values and steric congestion in titanocene and zirconocene moieties lead to various reaction products from bis(trimethylsilyl)acetylene complexes and hydrogen under atmospheric pressure.
The effect of electrolyte concentration on electrochemical impedance for evaluating polysulfone membranes
Authors: Huang Qing , Luo Qizhao , Chen Zhe , Yao Lei , Fu Ping , Lin Zhidong
Published: June 2018

Lower electrolyte concentration would result in the appearance of resistance–capacitor arc at high frequency.
Cyanidin 3-O-glucoside prevents the development of maladaptive cardiac hypertrophy and diastolic heart dysfunction in 20-week-old spontaneously hypertensive rats
Authors: Aloud Basma Milad , Raj Pema , McCallum Jason , Kirby Chris , Louis Xavier Lieben , Jahan Fahmida , Yu Liping , Hiebert Brett , Duhamel Todd A. , Wigle Jeffrey T. , Blewett Heather , Netticadan Thomas
Published: June 2018

Cyanidin 3-O-glucoside prevents ET1-induced cardiomyocytes hypertrophy and fibroblast differentiationin vitroand cardiac abnormalities in SHR.
The significance, trafficking and determination of labile iron in cytosol, mitochondria and lysosomes
Authors: Lv Huanhuan , Shang Peng
Published: June 2018

Progress in the research of the significance and trafficking of cellular labile iron in different subcellular compartments and the determination of cellular LIP by fluorescent methods have been reviewed.
Plasma-treated electrospun nanofibers as a template for the electrostatic assembly of silver nanoparticles
Authors: Liu Zhicheng , Jia Lu , Yan Zhaodong , Bai Lu
Published: June 2018

Silver nanoparticles assembled on a plasma treated electrospun nanofiber membrane could show excellent SERS effect.
A highly selective fluorescence turn-on chemosensor for Zn2+, and its application in live cell imaging, and as a colorimetric sensor for Co2+: experimental and TD-DFT calculations
Authors: Sohrabi Marzieh , Amirnasr Mehdi , Meghdadi Soraia , Lutz Martin , Bikhof Torbati Maryam , Farrokhpour Hossein
Published: June 2018

A highly sensitive quinoline based “dual” chemosensor used for fluorometric detection of Zn2+, live-cell imaging, and colorimetric detection of Co2+.
Removal of elemental mercury using titania sorbents loaded with cobalt ceria oxides from syngas
Authors: Li Xueqian , Zhou Jinsong , Zhou Qixin , Mao Juezhen
Published: June 2018

A novel CexCoyTi sorbent was synthesized, which exhibited high mercury removal efficiency at low temperature.
Bi-metallic boride electrocatalysts with enhanced activity for the oxygen evolution reaction
Authors: Zhang Jian , Li Xianxian , Liu Yiteng , Zeng Zhaowei , Cheng Xu , Wang Yadong , Tu Wenmao , Pan Mu
Published: June 2018

The introduction of a second metal in mono-metallic borides as catalysts for the oxygen evolution reaction significantly increases the catalytic activity.
Strong magnetoelectric coupling effect in BaTiO3@CoFe2O4 magnetoelectric multiferroic fluids
Authors: Gao Rongli , Zhang Qingmei , Xu Zhiyi , Wang Zhenhua , Cai Wei , Chen Gang , Deng Xiaoling , Cao Xianlong , Luo Xiaodong , Fu Chunling
Published: June 2018

Magnetoelectric multiferroic fluids composed of BaTiO3@CoFe2O4 composite nanoparticles dispersed in a highly insulating nonpolar oleic acid/silicone oil mixture have been developed.
The initial stages of ZnO atomic layer deposition on atomically flat In0.53Ga0.47As substrates
Authors: Skopin Evgeniy V. , Rapenne Laetitia , Roussel Hervé , Deschanvres Jean-Luc , Blanquet Elisabeth , Ciatto Gianluca , Fong Dillon D. , Richard Marie-Ingrid , Renevier Hubert
Published: June 2018

Growth per cycle. Visualizing the fabrication of a ZnO ultra-thin layer at the very early stage of ZnO ALD on InGaAs substrate, before the 3D growth mode begins.
Hierarchical FeS/RGO/FeS@Fe foil as high-performance negative electrode for asymmetric supercapacitors
Authors: Shao Xiaoxiao , Zhu Zhaoqiang , Zhao Chongjun , Zhao Chunhua , Qian Xiuzhen
Published: June 2018

A hierarchical FeS/RGO/FeS composite in situ grown on Fe foil was prepared, which exhibits excellent electrochemical performances in a supercapacitor.
Visual synchronization of two 3-variable Lotka–Volterra oscillators based on DNA strand displacement
Authors: Zou Chengye , Wei Xiaopeng , Zhang Qiang
Published: June 2018

DNA strand displacement as a theoretic foundation is helpful in constructing reaction networks and DNA circuits.
Entry and passage behavior of biological cells in a constricted compliant microchannel
Authors: Raj A. , Sen A. K.
Published: June 2018

We report an experimental and theoretical investigation of the entry and passage behaviour of biological cells (HeLa and MDA-MB-231) in a constricted compliant microchannel.
Stability of organometal halide perovskite solar cells and role of HTMs: recent developments and future directions
Authors: Raza Ehsan , Aziz Fakhra , Ahmad Zubair
Published: June 2018

This article gives the comprehensive review on the environmental stability issues of PSCs.
Highly crystalline Nb-doped TiO2 nanospindles as superior electron transporting materials for high-performance planar structured perovskite solar cells
Authors: Lv Yinhua , Cai Bing , Ma Qingshan , Wang Zenghua , Liu Jingyue(Jimmy) , Zhang Wen-Hua
Published: June 2018

Highly crystalline Nb:TiO2 nanospindles have been successfully exploited as efficient ETMs in planar perovskite solar cells, achieving a power conversion efficiency of 20.8%, superior to that of the undoped one (19.1%).
1,3-Phenylene-bridged naphthalene wheels synthesized by one-pot Suzuki–Miyaura coupling and the complex of the hexamer with C60
Authors: Mei Peifeng , Matsumoto Akinobu , Hayashi Hironobu , Suzuki Mitsuharu , Aratani Naoki , Yamada Hiroko
Published: June 2018

1,3-Phenylene-bridged cyclic hexa-naphthalene synthesized by Suzuki–Miyaura coupling via a one-pot reaction formed a co-crystal with C60 to exhibit a 1D alignment of fullerene.
Chemical studies on the parasitic plant Thonningia sanguinea Vahl
Authors: Thomford Ama Kyeraa , Ahmed Abdelhameed Reda Fouad , Yamada Koji
Published: June 2018

A detailed first-time report on plant sterols and one flavanone characterized from Thonningia sanguinea provides significant evidence for its ethnomedicinal usage.
Correction: Preparation of glycerol monostearate from glycerol carbonate and stearic acid
Authors: Han Li , Wang Tao
Published: June 2018

Correction for ‘Preparation of glycerol monostearate from glycerol carbonate and stearic acid’ by Li Han et al., RSC Adv., 2016, 6, 34137–34145.
Largely enhanced mechanical performance of poly(butylene succinate) multiple system via shear stress-induced orientation of the hierarchical structure
Authors: Xie Xu-Long , Li Yue , Xu Jia-Zhuang , Yan Zheng , Zhong Gan-Ji , Li Zhong-Ming
Published: June 2018

The simultaneous reinforcement and toughening of poly(butylene succinate) was achieved via an oriented hierarchical structure induced by oscillation shear stress and promoted by poly(l-lactide).
Elastic sandwich-type GaN/MnO2/MnON composites for flexible supercapacitors with high energy density
Authors: Wang Shouzhi , Shao Yongliang , Liu Weikang , Wu Yongzhong , Hao Xiaopeng
Published: June 2018

A novel flexible electrode with a sandwich structure consisting of double stabilizing buffer layers is designed and fabricated for the first time, and significant improvement in cycling stability and desired areal capacity is achieved. This strategy will allow large volume change metal oxide electrodes to be applied in energy storage and related fields.
Computer-aided design of short peptide ligands targeting tumor necrosis factor-alpha for adsorbent applications
Authors: Chen Jie , Sun Jixue , Han Wenyan , Chen Jian , Wang Weichao , Cheng Guanghui , Lin Jianping , Ma Nan , Chen Hao , Ou Lailiang , Li Wenzhong
Published: June 2018

A peptide ligand (T1: Ac-RKEM-NH2) designed by a computer-aided method can enhance TNF-α adsorption from the plasma of rats with sepsis to PVA.
The mitochondrial DNA genetic bottleneck: inheritance and beyond
Authors: Zhang Haixin , Burr Stephen P. , Chinnery Patrick F.
Published: June 2018

mtDNA is a multicopy genome. When mutations exist, they can affect a varying proportion of the mtDNA present within every cell (heteroplasmy). Heteroplasmic mtDNA mutations can be maternally inherited, but the proportion of mutated alleles differs markedly between offspring within one generation. This led to the genetic bottleneck hypothesis, explaining the rapid changes in allele frequency seen during transmission from one generation to the next. Although a physical reduction in mtDNA has been demonstrated in several species, a comprehensive understanding of the molecular mechanisms is yet to be revealed. Several questions remain, including the role of selection for and against specific alleles, whether all bottlenecks are the same, and precisely how the bottleneck is controlled during development. Although originally thought to be limited to the germline, there is evidence that bottlenecks exist in other cell types during development, perhaps explaining why different tissues in the same organism contain different levels of mutated mtDNA. Moreover, tissue-specific bottlenecks may occur throughout life in response to environmental influences, adding further complexity to the situation. Here we review key recent findings, and suggest ways forward that will hopefully advance our understanding of the role of mtDNA in human disease.
Mitochondrial DNA replication in mammalian cells: overview of the pathway
Authors: Falkenberg Maria
Published: June 2018

Mammalian mitochondria contain multiple copies of a circular, double-stranded DNA genome and a dedicated DNA replication machinery is required for its maintenance. Many disease-causing mutations affect mitochondrial replication factors and a detailed understanding of the replication process may help to explain the pathogenic mechanisms underlying a number of mitochondrial diseases. We here give a brief overview of DNA replication in mammalian mitochondria, describing our current understanding of this process and some unanswered questions remaining.
A new short-term forecasting model for the total electron content storm time disturbances
Authors: Tsagouri Ioanna , Koutroumbas Konstantinos , Elias Panagiotis
Published: June 2018

This paper aims to introduce a new model for the short-term forecast of the vertical Total Electron Content (vTEC). The basic idea of the proposed model lies on the concept of the Solar Wind driven autoregressive model for Ionospheric short-term Forecast (SWIF). In its original version, the model is operationally implemented in the DIAS system (http://dias.space.noa.gr) and provides alerts and warnings for upcoming ionospheric disturbances, as well as single site and regional forecasts of the foF2 critical frequency over Europe up to 24 h in advance. The forecasts are driven by the real time assessment of the solar wind conditions at ACE location. The comparative analysis of the variations in foF2 and vTEC during eleven geomagnetic storm events that occurred in the present solar cycle 24 reveals similarities but also differences in the storm-time response of the two characteristics with respect to the local time and the latitude of the observation point. Since the aforementioned dependences drive the storm-time forecasts of the SWIF model, the results obtained here support the upgrade of the SWIF’s modeling technique in forecasting the storm-time vTEC variation from its onset to full development and recovery. According to the proposed approach, the vTEC storm-time response can be forecasted from 1 to 12–13 h before its onset, depending on the local time of the observation point at storm onset at L1. Preliminary results on the assessment of the performance of the proposed model and further considerations on its potential implementation in operational mode are also discussed.
Mehr als kleine Erwachsene
Authors: Bittner Sebastian
Published: June 2018

Fast jede Fortbildung und auch fast jeder Artikel zum Thema Anästhesie bei Kindern oder Säuglingen startet mit den Worten „Kinder sind keine kleinen
Erwachsenen!“. Doch was verbirgt sich dahinter? Was sind anatomische Besonderheiten und was sind die Anforderungen an die psychische Betreuung von Kindern im
Rahmen einer Anästhesie? In welche Altersgruppen lassen sich „Kinder“ klinisch relevant einteilen? Dieser CNE-Schwerpunkt soll eine Zusammenfassung der
wichtigsten und pflegerischen Besonderheiten der kleinen Patienten aufzeigen und geht besonders auf die vorbereitenden Maßnahmen ein.
Ultrasound Nomograms of the Fetal Optic Nerve Sheath Diameter
Authors: Haratz Karina Krajden , Melcer Yaakov , Leibovitz Zvi , Feit Hagit , Lerman-Sagie Tally , Lev Dorit , Ginath Shimon , Gindes Liat , Moron Antonio Fernandes , Malinger Gustavo
Published: June 2018

Objective To construct prenatal age-specific reference intervals for sonographic measurements of the optic nerve sheath diameter (ONSD) during gestation in normal fetuses.

Materials and Methods Prospective cross-sectional study of fetuses assessed in antenatal ultrasound units between 2010 and 2014. The examination was based on a technique for the sonographic assessment of ONSD previously published by our group. The mean values and SDs of the ONSD were modeled as a function of the gestational week by curve estimation analysis based on the highest adjusted R2 coefficient. Repeatability tests were performed to assess intraobserver variability and interobserver agreement.

Results During the study period 364 healthy fetuses were enrolled. The mean values for the ONSD varied from 0.6 mm at 15–16 weeks to 2.8 mm at 37–38 weeks. The ONSD grows in a linear fashion throughout gestation, with a quadratic equation providing an optimal fit to the data (adjusted R2 = 0.957).

Conclusion Sonographic age-specific references for the fetal ONSD are presented. This data may assist in the decision-making process in fetuses with a suspected increase in intracranial pressure, or anomalies affecting the development of optic stalks, such as optic hypoplasia and septo-optic dysplasia.
Rechtskolumne: Privatadressen der Ärzte bleiben
Authors: Häser Isabe
Published: June 2018

Patienten haben im Streitfall mit Kliniken keinen pauschalen Auskunftsanspruch über Namen und Privatanschriften von behandelnden Ärzten. Das geht aus einem Beschluss des Oberlandesgerichts Hamm hervor.
Manager des Jahres 2018: Thieme Management Award: Reichen Sie Ihre Vorschläge bei uns ein!
Authors: Freye Carolin
Published: June 2018

Mit den Auszeichnungen „Manager des Jahres“ und „Senkrechtstarter“ ehren die Thieme Gruppe und kma Persönlichkeiten aus dem Management in der deutschen Gesundheitswirtschaft, die sich in den letzten 12 bis 18 Monaten durch besonderes Wirken ausgezeichnet haben. Die Preisverleihung findet traditionell gemeinsam mit dem cdgw – Club der Gesundheitswirtschaft auf einer exklusiven Gala im Januar statt. Nutzen Sie die Chance und schlagen Sie uns Ihren Wunschkandidaten vor! Bewerbungsschluss ist der 31.8.2018. Ausführliche Informationen zu den Auszeichnungen, den früheren Preisträgern, der Jury und der Gala finden Sie auf: www.kma-online.de/awards
Internet der Dinge: Wie schütze ich meinen Fahrstuhl vor Cyberpiraten?
Authors: Thoss Michael
Published: June 2018

Die Versorgungstechnik des Krankenhauses digitalisiert sich gerade. Ob Schranken, Heizungen, Jalousien oder Fahrstühle – alles wird perspektivisch online gesteuert. Das „Internet der Dinge“ bietet viele Chancen, aber auch Angriffsflächen: Fallen etwa Aufzüge einer Klinik durch eine Cyberattacke zwei Stunden aus, steht der Krankenhausbetrieb teilweise still.
Dräger Design Center: OP-Ausstattung live planen
Authors: Grether Thomas
Published: June 2018

Eigentlich ist die Planung einer OP-Ausstattung der einer Küche vergleichbar. Erst wer die Objekte anfassen kann, weiß, ob sie am richtigen Platz sind. Deswegen hat Draeger ein Design-Center entwickelt, in dem OP-Fachkräfte alle Handgriffe ausprobieren können. Erst dann wird bestellt.
Krankenhauspersonal: Weiterbildung für Krankenhaustechniker muss mehr gefördert werden
Authors: Bender Christian
Published: June 2018

Das Forum DACH, bestehend aus den Fachverbänden FKT, ÖVKT, IHS und NVTG hat eine Arbeitsgruppe zur Erstellung eines einheitlichen Berufsbildes für Technikmanager im Gesundheitswesen gebildet. Ziel ist die gesetzliche Verankerung dieses Berufsbildes. WGKT-Vorstand Christian Bender arrangierte ein Gespräch mit Staatsminister Dr. Helge Braun und begleitete zusammen mit WGKT-Präsident Cord Brüning die Präsidenten der DACH-Verbände ins Kanzleramt, um auf notwendige politische Maßnahmen aufmerksam zu machen.
Elektronische Schliessanlage: Alles unter Kontrolle
Authors: Lambach Sylvia
Published: June 2018

Das Beispiel der Kliniken Maria Hilf in Mönchengladbach zeigt die Möglichkeiten bei der Schlüsselausgabe und -verwaltung auf, die ein elektronisches Schließsystem Krankenhäusern bieten kann.
Normalisierung der Blutungszeit durch Traumatisierung des Gewebes bei Patienten mit der åländischen Blutungskrankheit (v. Willebrand-Jürgens)
Authors: Wegelius Otto
Published: June 2018

Bei 12 von 16 untersuchten Patienten auf Aland mit dem v. Willebrand-Jürgensschen Blutungsübel im aktiven Stadium war eine Normalisierung der verlängerten Blutungszeit durch Traumatisierung des Ohrläppchengewebes möglich. Bei 2 Personen erfolgte eine bedeutende Verkürzung der Blutungszeit und in 2 Fällen trat eine Verlängerung derselben ein. Die Resultate werden diskutiert. Die Ursache des Effektes der Traumatisierung auf die Blutungszeit ist noch unklar.
The use of Anticoagulants in Cardiology
Authors: Formijne P
Published: June 2018

The possibilities of myocardial infarction-therapy with anticoagulants is discussed. It is important to consider, that although patients with acute myocardial infarction may be in a relatively good condition at home a transfer to the hospital may evidence fatal complications resulting from the traumatic shock inflicted during transport. The benefit of installing early anticoagulant therapy is decisive, but not at the expense of danger to the patient in getting him to a hospital to start treatment. It is suggested that the patient be left at home until he has partially recovered from the acute effects of the coronary occlusion. When doing necropsies on patients with fresh myocardial infarctions treated with anticoagulants, one frequently finds an infiltration of the infarction with blood and ruptures of the ventricle.
Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review
Authors: van der Vorm Lisa , Remijn Jasper , de Laat Bas , Huskens Dana
Published: June 2018

Plasmin is the major fibrinolytic protease responsible for dissolving thrombi by cleavage of its primary substrate fibrin. In addition, emerging evidence points to other roles of plasmin: (1) as a back-up for ADAMTS13 in proteolysis of ultra-large von Willebrand factor (VWF) multimers and (2) as an activator of platelets. Although the molecular mechanisms of fibrinolysis are well defined, insights on the effects of plasmin on VWF and platelets are relatively scarce and sometimes conflicting. Hence, this review provides an overview of the literature on the effects of plasmin on VWF multimeric structures, on VWF binding to platelets, and on platelet activation. This information is placed in the context of possible applications of thrombolytic therapy for the condition thrombotic thrombocytopenic purpura.
Rem-Tracker
Authors: Gauger Friedrich , Schroff Gerhart , Stork Wilhelm
Published: June 2018

Die Behandlung von Albträumen erfolgt bislang meist psychotherapeutisch. Ein in der Praxis bewährtes Verfahren ist die Imagery Rehearsal Therapy (IRT). Untersuchungen zeigen, dass die Effektivität der IRT erhöht werden kann, wenn der Patient die Fähigkeit zum Klarträumen erlangt. Die gängige Technologie zur Klartrauminduktion kann bislang nur in entsprechend qualifizierten Schlaflaboren eingesetzt werden.

Der REM-TRACKER bietet erstmals die Möglichkeit der Klartrauminduktion mittels einer einfach handhabbaren Technologie, die auch im häuslichen Umfeld eingesetzt werden kann.
Nutzt eine CPAP-Therapie bei obstruktiver Schlafapnoe und kardiovaskulärer Grunderkrankung?
Authors: Herkenrath Simon
Published: June 2018

Die obstruktive Schlafapnoe (OSA) ist durch einen repetitiven partiellen oder vollständigen Verschluss der oberen Atemwege im Schlaf charakterisiert. Die daraus resultierenden Schwankungen des Atemflusses bewirken wiederkehrende Desaturationen, die häufig erst zusammen mit unterschwelligen Weckreaktionen („Arousals”) mit kurzfristiger Anspannung der dilatatorischen Muskeln der oberen Atemwege terminiert werden. Man geht inzwischen davon aus, dass 6–20 % Prozent der Bevölkerung an einer obstruktiven Schlafapnoe leiden, bei Männern jenseits des 40. Lebensjahr liegt die Prävalenz sogar bei über 40 % (1).
Auswirkungen von Schlafrestriktion und Erholung auf die Motivation während wiederholter kognitiver Leistungstests
Authors: Lange Denise
Published: June 2018

“Zu anderen Konferenzbeginnen werde ich normalerweise um 10 Uhr eingeladen, deswegen war ich umso überraschter, dass die diesjährige Jahrestagung der Deutschen Gesellschaft für Schlafforschung und Schlafmedizin schon um 08:30 Uhr startet”. So begrüßte Herr Markus Lewe, der Oberbürgermeister von Münster, mit dem ersten Lacher am Morgen die Mitglieder der 25. Jahrestagung.
Towards massively parallelized all-optical magnetic recording
Authors: Davies C. S. , Janušonis J. , Kimel A. V. , Kirilyuk A. , Tsukamoto A. , Rasing Th. , Tobey R. I.
Published: June 2018

We demonstrate an approach to parallel all-optical writing of magnetic domains using spatial and temporal interference of two ultrashort light pulses. We explore how the fluence and grating periodicity of the optical transient grating influence the size and uniformity of the written bits. Using a total incident optical energy of 3.5 μJ, we demonstrate the capability of simultaneously writing 102 spatially separated bits, each featuring a relevant lateral width of ∼1 μm. We discuss viable routes to extend this technique to write individually addressable, sub-diffraction-limited magnetic domains in a wide range of materials.
Negative effect of driving power on far-field sound energy density in cavitating liquids
Authors: Wang Xun , Chen Weizhong , Yang Jing , Liang Shengde
Published: June 2018

The distributions of total sound energy density in cavitating liquids in a long container were reported. The total far-field energy density abnormally decreased with increasing the driving power, demonstrating the negative effect of the driving power on the far-field sound energy density. This effect could not be attributed to the classical damping and scattering of cavitation bubbles. Spectral analysis revealed that when the sound pressure was a little above the cavitation threshold, the sound energy transferred to harmonics did not constitute a large fraction of the total sound energy. However, by continuously improving the pressure, the proportion of harmonic energy evidently increased, owing to the strong nonlinear effect of cavitation bubbles. For a propagating sound wave, the harmonics attenuated faster than the fundamental ones, which resulted in an unexpectedly less sound energy reaching far field under high driving, compared with low driving. As a result, the negative effect appeared. Further experiments revealed that the size of the region in which the negative effect appeared depended not only on the driving power but also on the cavitation threshold of the host liquid, and the negative effect disappeared when the driving power was decreased or when using liquids with a high cavitation threshold.
Kinematical Lie algebras via deformation theory
Authors: Figueroa-O’Farrill José M.
Published: June 2018

We present a deformation theory approach to the classification of kinematical Lie algebras in 3 + 1 dimensions and present calculations leading to the classifications of all deformations of the static kinematical Lie algebra and of its universal central extension, up to isomorphism. In addition, we determine which of these Lie algebras admit an invariant symmetric inner product. Among the new results, we find some deformations of the centrally extended static kinematical Lie algebra which are extensions (but not central) of deformations of the static kinematical Lie algebra. This paper lays the groundwork for two companion papers which present similar classifications in dimension D + 1 for all D⩾4 and in dimension 2 + 1.
MSM/RD: Coupling Markov state models of molecular kinetics with reaction-diffusion simulations
Authors: Dibak Manuel , del Razo Mauricio J. , De Sancho David , Schütte Christof , Noé Frank
Published: June 2018

Molecular dynamics (MD) simulations can model the interactions between macromolecules with high spatiotemporal resolution but at a high computational cost. By combining high-throughput MD with Markov state models (MSMs), it is now possible to obtain long time-scale behavior of small to intermediate biomolecules and complexes. To model the interactions of many molecules at large length scales, particle-based reaction-diffusion (RD) simulations are more suitable but lack molecular detail. Thus, coupling MSMs and RD simulations (MSM/RD) would be highly desirable, as they could efficiently produce simulations at large time and length scales, while still conserving the characteristic features of the interactions observed at atomic detail. While such a coupling seems straightforward, fundamental questions are still open: Which definition of MSM states is suitable? Which protocol to merge and split RD particles in an association/dissociation reaction will conserve the correct bimolecular kinetics and thermodynamics? In this paper, we make the first step toward MSM/RD by laying out a general theory of coupling and proposing a first implementation for association/dissociation of a protein with a small ligand (A + B ⇌ C). Applications on a toy model and CO diffusion into the heme cavity of myoglobin are reported.
Characterization of bulk traps and interface states in AlGaN/GaN heterostructure under proton irradiation
Authors: Zheng Xue-Feng , Dong Shuai-Shuai , Ji Peng , Wang Chong , He Yun-Long , Lv Ling , Ma Xiao-Hua , Hao Yue
Published: June 2018

This paper provides a systematic study on the bulk traps and interface states in a typical AlGaN/GaN Schottky structure under proton irradiation. After 3 MeV proton irradiation with a dose of 5 × 1014 H+/cm2, a positive flat band voltage shift of 0.3 V is observed according to the capacitance-voltage (C-V) measurements. Based on this, the distribution of electrons across AlGaN and GaN layers is extracted. Associated with the numerical calculation, direct experimental evidences demonstrate that the bulk traps within the AlGaN layer dominate the carrier removal effect under proton irradiation. Furthermore, the effects of proton irradiation on AlGaN/GaN interface states were investigated by utilizing the frequency dependent conductance technique. The time constants are extracted, which increase from 1.10–2.53 μs to 3.46–37 μs after irradiation. Meanwhile, it shows that the density of interface states increases from 9.45 × 1011–1.70 × 1013 cm−2·eV−1 to 1.8 × 1012–1.8 × 1013 cm−2·eV−1 with an increase in trap activation energy from 0.34 eV–0.32 eV to 0.41 eV–0.35 eV after irradiation. The Coulomb scattering effect of electron trapping at interface states with deeper energy levels is utilized to explain the mobility degradation in this paper.
Quantum recovery protocols for stabilizer codes: Deterministic Monte-Carlo simulation
Authors: Prousalis Konstantinos , Iliadis Agis , Konofaos Nikos
Published: June 2018

The quantum noise encumbrance caused by quantum error-correcting protocols is studied via numerical treatments. Noise evolution implies that the noise magnitude order may change dynamically during quantum computations. The rate of noise level deterioration is a function of the computer’s architecture and physical implementation. Various stabilizer codes with small blocks are studied under dynamic noise regimes, which change the noise magnitude order within a specified time period. The Monte-Carlo sampling simulation method is used to determine the survival probabilities for these codes under evolving error rates. A hypothetical q-step quantum algorithm is stabilized by the repeated application of the recovery protocol, and the proposed estimation method is applied. The estimation method is applied concurrently with the execution of the algorithm. The recovery process is simulated with the aid of a software tool that can be parameterized based on the noise model and the encoding error-correction scheme. Examples show the utility of this tool for quantum coding studies.
Neural network method for lossless two-conductor transmission line equations based on the IELM algorithm
Authors: Yang Yunlei , Hou Muzhou , Luo Jianshu , Liu Taohua
Published: June 2018

With the increasing demands for vast amounts of data and high-speed signal transmission, the use of multi-conductor transmission lines is becoming more common. The impact of transmission lines on signal transmission is thus a key issue affecting the performance of high-speed digital systems. To solve the problem of lossless two-conductor transmission line equations (LTTLEs), a neural network model and algorithm are explored in this paper. By selecting the product of two triangular basis functions as the activation function of hidden layer neurons, we can guarantee the separation of time, space, and phase orthogonality. By adding the initial condition to the neural network, an improved extreme learning machine (IELM) algorithm for solving the network weight is obtained. This is different to the traditional method for converting the initial condition into the iterative constraint condition. Calculation software for solving the LTTLEs based on the IELM algorithm is developed. Numerical experiments show that the results are consistent with those of the traditional method. The proposed neural network algorithm can find the terminal voltage of the transmission line and also the voltage of any observation point. It is possible to calculate the value at any given point by using the neural network model to solve the transmission line equation.
Band alignment at β-(AlxGa1−x)2O3/β-Ga2O3 (100) interface fabricated by pulsed-laser deposition
Authors: Wakabayashi Ryo , Hattori Mai , Yoshimatsu Kohei , Horiba Koji , Kumigashira Hiroshi , Ohtomo Akira
Published: June 2018

High-quality β-(AlxGa1−x)2O3 (x = 0–0.37) films were epitaxially grown on β-Ga2O3 (100) substrates by oxygen-radical-assisted pulsed-laser deposition with repeating alternate ablation of single crystals of β-Ga2O3 and α-Al2O3. The bandgap was tuned from 4.55 ± 0.01 eV (x = 0) to 5.20 ± 0.02 eV (x = 0.37), where bowing behavior was observed. The band alignment at the β-(AlxGa1−x)2O3/β-Ga2O3 interfaces was found to be type-I with conduction- and valence-band offsets of 0.52 ± 0.08 eV (0.37 ± 0.08 eV) and 0.13 ± 0.07 eV (0.02 ± 0.07 eV) for x = 0.37 (0.27), respectively. The large conduction-band offsets are ascribed to the dominant contribution of the cation-site substitution to the conduction band.
Low temperature plasmas induced in SF6 by extreme ultraviolet (EUV) pulses
Authors: Bartnik A. , Skrzeczanowski W. , Czwartos J. , Kostecki J. , Fiedorowicz H. , Wachulak P. , Fok T.
Published: June 2018

In this work, a comparative study of extreme ultraviolet (EUV) induced low temperature SF6-based plasmas, created using two different irradiation systems, was performed. Both systems utilized laser-produced plasma (LPP) EUV sources. The essential difference between the systems concerned the formation of the driving EUV beam. The first one contained an efficient ellipsoidal EUV collector allowing for focusing of the EUV radiation at a large distance from the LPP source. The spectrum of focused radiation was limited to the long-wavelength part of the total LPP emission, λ > 8 nm, due to the reflective properties of the collector. The second system did not contain any EUV collector. The gas to be ionized was injected in the vicinity of the LPP, at a distance of the order of 10 mm. In both systems, energies of the driving photons were high enough for dissociative ionization of the SF6 molecules and ionization of atoms or even singly charged ions. Plasmas, created due to these processes, were investigated by spectral measurements in the EUV, ultraviolet (UV), and visible (VIS) spectral ranges. These low temperature plasmas were employed for preliminary experiments concerning surface treatment. The formation of pronounced nanostructures on the silicon surface after plasma treatment was demonstrated.
Role of spontaneous strains on the biphasic nature of partial B-site disorder double perovskite La2NiMnO6
Authors: Yang Dexin , Wang Wei , Yang Tao , Lampronti Giulio I. , Ye Huijian , Wu Liankui , Yu Qiyao , Lu Shaohua
Published: June 2018

Double perovskite La2NiMnO6 is an attractive spintronic material with magnetocapacitance and magnetoresistance effects. These outstanding properties are associated with the biphasic characteristic and anti-site defects. To study the biphasic nature of La2NiMnO6, the spontaneous shear strains, crystal structures, microstructures, element distribution, and magnetic properties were investigated. The first principles density functional theory calculations within the Perdew-Burke-Ernzerhof functional were first used to calculate the static formation enthalpies and crystal structures of La2NiMnO6 at different hydrostatic pressures. The coexistence is most likely related to static formation enthalpies and/or spontaneous strains and partly due to the inhomogeneous characteristics of the sample.
Bright single photon sources in lateral silicon carbide light emitting diodes
Authors: Widmann Matthias , Niethammer Matthias , Makino Takahiro , Rendler Torsten , Lasse Stefan , Ohshima Takeshi , Ul Hassan Jawad , Tien Son Nguyen , Lee Sang-Yun , Wrachtrup Jörg
Published: June 2018

Single-photon emitting devices have been identified as an important building block for applications in quantum information and quantum communication. They allow us to transduce and collect quantum information over a long distance via photons as so-called flying qubits. In addition, substrates like silicon carbide provide an excellent material platform for electronic devices. In this work, we combine these two features and show that one can drive single photon emitters within a silicon carbide p-i-n-diode. To achieve this, we specifically designed a lateral oriented diode. We find a variety of new color centers emitting non-classical lights in the visible and near-infrared range. One type of emitter can be electrically excited, demonstrating that silicon carbide can act as an ideal platform for electrically controllable single photon sources.
Vibrational modes of dopant defects in gallium oxide reveal hydrogen’s role
Authors: De Jarnette Drew
Published: June 2018

Experimental vibrational modes of hydrogen defects in gallium oxide have been attributed to hydrogen bound to vacancies in the semiconductor matrix, which can vary the intended conductivity.
RNA sequencing and differential expression reveals the effects of serial oestrus synchronisation on ovarian genes in dairy goats
Authors: Sun Shuang , Li Cong , Liu Shimin , Luo Jun , Chen Zhi , Zhang Changhui , Zhang Tianying , Huang Jiangtao , Xi Limeng
Published: June 2018

A total of 24 female Xinong Saanen dairy goats were used to examine differentially expressed genes (DEGs) in the ovaries of goats treated once or three times for oestrus synchronisation (ES). The goats were randomly divided into two groups: one group received three ES treatments at fortnightly intervals (repeated or triple ES group), whereas the other was only treated once on the same day as the third ES treatment for the triple group (control group) during the breeding season. Ovaries of three goats in oestrus from each group were collected for morphological examination and transcriptome sequencing, while the rest of the goats were artificially inseminated twice. Litter size and fecundity rate tended (P = 0.06) to be lower in the triple ES group. A total of 319 DEGs were identified, including carbohydrate sulphotransferase 8 (CHST8), corticosteroid-binding globulin (CBG), oestradiol 17-β-dehydrogenase 1 (DHB1), oestrogen receptor 1 (ESR1), progestin and adipoQ receptor family member 4 (PAQR4), PAQR9, prostacyclin synthase (PTGIS), contactin-associated protein (CNTNAP4), matrix metalloproteinase-2 (MMP-2), regulator of G-protein signalling 9-2 (RGS9-2) and sperm surface protein Sp17 (Sp17); these were the most promising novel candidate genes for reproductive performances in goats. Our study indicates that triple ES could cause DNA damage and alter gene expression in goat ovaries, potentially affecting ovary function, neural regulation and hormone secretion.
Influence of axial force parameters to the quality of friction pull plug welding for 2219-T87 aluminium alloy sheets
Authors: Cui Lei , Lu Peng , Li Wukai , Wang Huimiao , Wang Dongpo , Zhang Zhongping , Song Jianling
Published: June 2018

In this study, we performed a friction pull plug welding process successfully on 8-mm-thick 2219-T87 plates. The influence of the welding process on the weld formation and defects are investigated. The defect characters, grain structures, precipitate evolutions and tensile properties of the weld are examined. It was found that the axial force plays a crucial role in influencing the weld formation and defect characters. In thermal mechanically affect zone nearby the bonding interface, the grains might be highly deformed and recrystallised owing to the severe plastic deformation. Besides, the strengthening precipitates might be dissolved during welding. Near the bonding interface, as the hardening effects from cold work and precipitation have been weakened, the hardness in this region was reduced obviously. The ultimate tensile strength and elongation of defect free welds may reach 310 MPa and 6.5% respectively. This reveals that FPPW technology has the potential for the application in aerospace industrial field.
Data, Evidence, and Explanatory Power
Authors: Ströing Pascal
Published: June 2018

Influential classical and recent approaches to explicate confirmation, explanation, or explanatory power define these relations or degrees between hypotheses and evidence. This holds for both deductive and Bayesian approaches. However, this neglects the role of data, which for many everyday and scientific examples cannot simply be classified as evidence. I present arguments to sharply distinguish data from evidence in Bayesian approaches. Taking into account this distinction, we can rewrite Schupbach and Sprenger’s measure of explanatory power and show the strengths of this adaptation by applying it to the example of the detection of gravitational waves in physics.