bluuebunny/crossref_metadata_2025 huggingface dataset:
SIMPD: an Algorithm for Generating Simulated Time Splits for Validating Machine Learning Approaches
Authors: Landrum Gregory A. , Beckers Maximilian , Lanini Jessica , Schneider Nadine , Stiefl Nikolaus , Riniker Sereina
Published: September 2023

Time-split cross-validation is broadly recognized as the gold standard for validating predictive models intended for use in medicinal chemistry projects. Unfortunately this type of data is not broadly available outside of large pharmaceutical research organizations. Here we introduce the SIMPD (simulated medicinal chemistry project data) algorithm to split public data sets into training and test sets that mimic the differences observed in real-world medicinal chemistry project data sets. SIMPD uses a multi-objective genetic algorithm with objectives derived from an extensive analysis of the differences between early and late compounds in more than 130 lead-optimization projects run within the Novartis Institutes for BioMedical Research. Applying SIMPD to the real-world data sets produced training/test splits which more accurately reflect the differences in properties and machine-learning performance observed for temporal splits than other standard approaches like random or neighbor splits. We applied the SIMPD algorithm to bioactivity data extracted from ChEMBL and created 56 public data sets which can be used for validating machine-learning models intended for use in the setting of a medicinal chemistry project. The SIMPD code and simulated data sets are available under open-source/open-data licenses at github.com/rinikerlab/molecular_time_series.
The Effects of Metformin and Myo-Inositol on Hyperandrogenism, Insulin Sensitivity, and Fertility in Polycystic Ovary Syndrome: A Literature Review
Authors: Matossian Garene A. , Buklarewicz Isabella M. , Moosa Vaneeza A.
Published: September 2023

Introduction: Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder that occurs due to a hormone imbalance in the ovaries. It can cause the development of fluid-filled cysts on the follicles, causing infertility. Further, PCOS can cause insulin resistance and hyperandrogenism, increasing the amount of glucose and testosterone levels in the body. As a result, PCOS symptoms could include irregular or absent periods, weight gain, hirsutism, and more. PCOS patients are also at higher risk of developing type 2 diabetes, depression, and high blood pressure. Currently, there are no cures for PCOS, but it can be managed with lifestyle changes, contraceptive pills for irregular periods, and fertility treatments. Two of these treatments include inositol and metformin. The objective of the study is to ascertain how these therapies affect PCOS symptoms such as hyperandrogenism, insulin sensitivity, and infertility. Methods: Primary articles were found through the PubMed and OVID-Medline databases to investigate the effect of inositol or metformin on PCOS. Keywords such as PCOS, inositol, metformin, myo-inositol, insulin sensitivity, androgens, and fertility were used. Research published before 2010 was excluded. Results: The results found that metformin and inositol decreased the amounts of free testosterone and glucose in women with PCOS. Further, oocyte quality and production were improved in women taking metformin and inositol. These results were seen in women of all ages and of all BMIs. Discussion: Both metformin and MI are shown to significantly improve PCOS symptoms of hyperandrogenism, insulin sensitivity, and fertility issues. Although some limitations were present within the review and the studies examined due to exclusions, the review presents a comprehensive outlook on the impact of the interventions mentioned. Establishing a foundation for clinical trials would allow for the integration of these interventions into healthcare settings. Conclusion: A combination of both metformin and inositol, as well as diet and lifestyle changes can significantly improve the symptoms and life quality of individuals with PCOS. Future research would benefit from further studies done into investigating the combined effects of metformin and MI, as well as further assessment of secondary symptoms, as well as regarding the dosage of myo-inositol and metformin.
METODE DIRECT UNTUK MENGETAHUI NET PLANT HEAT RATE UNIT #2 PLTU REMBANG PADA SAAT OVERHAUL UNIT #1
Authors: Satria Harfani
Published: September 2023

Ketersedian energi listrik di sistem Jawa–Bali di dukung oleh beberapa pusat pembangkit listrik melalui jalur tansmisi voltase tinggi 150 kV dan voltase ektra tinggi 500 kV untuk berlangsungnya ketersediaan energi listrik secara andal dan terus–menerus. PLTU Rembang memiliki 2 unit yaitu unit #1 (#20) dan unit #2 (#10) yang memasok sistem transmisi 150 kV. Performa unit sangat menentukan dalam pemenuhan tersebut. Pusat Pengatur Beban (P2B) akan memilih pembebanan PLTU berdasarkan merit order. Merit order adalah tingkat prioritas suatu pembangkit termal untuk di dispatch dalam suatu sistem. Hal ini disebabkan oleh net plant heat rate (NPHR) dan harga bahan bakar. Akibat yang terjadi pada pembangkit dengan peringkat merit order rendah akan diprioritaskan turun beban terlebih dahulu atau naik beban paling akhir. NPHR merupakan salah satu indeks kinerja pembangkit termal. Semakin rendah NPHR maka semakin tinggi efisiensi pembangkit tersebut. Permasalahan yang terjadi dalam penentuan NPHR PLTU Rembang saat 2 unit beroperasi adalah kurang akurat karena beban listrik pemakaian sendiri masing-masing unit tidak berasal seluruhnya dari gross output generatornya, melainkan juga dibebankan oleh unit yang satunya. Terutama untuk pemakaian unit common seperti water treatment plant (WTP), desalination plant serta coal & ash handling plant karena di suplai oleh salah satu unit. Solusinya dengan mencari nilai NPHR ketika salah satu unit shutdown, agar dapat diketahui nilai NPHR yang lebih akurat.Penelitian  ini membahas tentang penggunaan metode direct untuk mencari NPHR pada unit #2 PLTU Rembang ketika unit #1 sedang overhaul. Metode direct adalah metode input-output yang hanya memerlukan bahan bakar sebagai input dan daya listrik sebagai output. Batubara yang digunakan adalah jenis low rank coal (LRC) senilai 4200–4500 kcal dan medium rank coal (MRC) senilai 4500–4800 kcal. Gross output generator memiliki rated power 300 MW sedang daya untuk pemakaian sendiri memiliki rated power 50 MVA. Nilai NPHR ditentukan dengan menghitung perkalian konsumsi dan nilai kalori batubara dibagi terhadap nett output generator. Nett ouput generator ditentukan dengan mengurangi gross output generator terhadap daya pemakain sendiri Trafo Universal Auxiliary Transformer. Hasil menunjukan bahwa NPHR memiliki nilai paling rendah jika unit berbeban maksimum 300 MW gross. Dari hasil perhitungan didapati bahwa pada  beban  rata-rata  299,5  MW  hingga  302,4  MW  gross,  NPHR  rata-rata pada  unit  #2  ketika  overhaul  lebih  rendah  dibanding  dengan  data  PLN Puslitbang  Januari  2017  yaitu  masing–masing  2.544,34  kcal/kWh  dan  2.788 kcal/kWh.  Demikian  pula  NPHR  unit  #2  sebelum  dan  sesudah  overhaul  unit #1 masing–masing  2.497 kcal/kWh dan 2.688 kcal/kWh   . Sedang  faktor-faktor yang menentukan nilai NPHR antara lain  pembebanan listrik,  nilai kalor bahan bakar serta pemakaian listrik untuk keperluan sendiri.
Factors of efficient use of water resources during drip irrigation of carrots in the conditions of the Lower Volga region
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Dubenok N. N. , Penkova R. I.
Published: September 2023

Every year, the volume of imports of vegetables, including table carrots, is growing. The above is the main indicator of the existence of a problem in providing the domestic market with domestically produced products. This is primarily due to the amount of resources expended and their high cost, which does not allow domestic producers to meet the population’s need for vegetables. The purpose of the study is to identify the degree of influence of various factors on the efficiency of water resources use during drip irrigation of carrots with the formation of 90‑130 t/ha of standard root crops. The experiment was carried out on the territory of the Volgograd region on the fields of the peasant farm of Zaitsev V.A. Three factors are defined in the scheme of the experiment: A – water supply conditions, B – mineral nutrition, C – sowing density. A change in the quantitative indicators of the main crop-forming factors leads to a change in the yield of marketable carrot products. Improved conditions created during the years of research (2019‑2021) on variants with the maximum dose of applied nutrients under a regime of differentiated soil moisture of 70‑80% HB in a layer of 0.4 m made it possible to obtain the highest yields (up to 114‑115 t/ha), however, the lowest consumption of irrigation moisture was noted for each year of research on the variant with maintaining the specified regime in a layer of 0.4 m, applying mineral fertilizers at a dose of N210P95K260 and differentiated distribution of seed material in the tape, where the amount of the resulting product reached 105‑113 t/ha.
Technologies and technical means of reclamation of fallow lands with regulation of the level of soil moisture
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Sevryugina N. S. , Apatenko A. S. , Golubev I. G. , Gustov Yu. I. , Fomin A. Yu.
Published: September 2023

An assessment of the technological feasibility of the tasks of involving fallow lands in agricultural circulation and increasing the fertility of agricultural land in the long-term period of economic activity is given. Insufficient information content of the use of yield maps for assessing the fertility of fields has been revealed. It is proposed to use maps of the relief of fields, which will allow establishing the dynamics of violation of the water-air regime of the soil. It is substantiated that in the process of involving fallow lands into circulation, it is required to introduce a technological operation of micro topographic analysis of the degree of soil moisture. An algorithm for switching on the field leveling operation (surface leveling of the field plane) using modern positioning systems has been developed. It was revealed that leveling the field with a laser level made it possible to reduce yield fluctuations by 20% within the cultivated area of the field and increase yield by 25‑30% (an example of sowing corn). Shortcomings of positioning accuracy with the use of laser and satellite positioning have been established. It is proposed to transfer digital information transmission modules to network clusters with the choice of the best digital data transmission channel by including an uninterrupted positioning module with digital data transmission over a 434 MHz and 864 MHz radio channel with a range of up to 600 meters to other digital information transmission modules of the vehicle positioning. A plan for the implementation of the concept of forming a digital field on the basis of a field experimental station of the RSAU-MAA named after C.A. Timiryazev, with the aim of creating a frontier for the sustainable development of closed life cycle technologies through the introduction of innovations using the multiplicative interaction of mechatronic systems and telematics for agro-industrial complex equipment
Changes in hydrothermal conditions in the arable layer of chernozem when mulching with cut straw
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Bekhovykh Yu. V. , Bekhovykh L. A.
Published: September 2023

The research goal was to study the trends in the influence of the mulching layer of cut straw on the change in hydrothermal conditions of the arable soil layer. The object of study was one of the most common soils of the Altai region – leached loamy chernozem. The plots for the experiment were laid on a steam field. One of the sections was mulched on the surface with a layer of cut straw 10‑15 mm thick, on the other section the mulch layer was 20‑25 mm. The third section of the black vapor was used for contrast control measurements. According to the measurements, it was revealed that in the mulched observation areas there was a noticeable decrease in soil temperature during the daytime both on the surface and in the entire arable layer compared to the control one. At night, a layer of cut straw prevented a sharp change in temperatures and contributed to the preservation of heat. The thickness of the mulching layer determined the temperature values of the arable layer during the daytime and at night. A layer of mulch on the soil surface contributed to the preservation of soil moisture reserves in the arable soil horizon. With an increase in the size of the mulching layer, there was a tendency for better moisture retention. The use of mulching of the surface layer of the soil with cut straw is advisable in arid regions to reduce the absolute values of the temperatures of the arable layer and reduce the evaporation of soil moisture from its surface, as well as to preserve moisture in the arable horizon of the soil.
Brain Respiration untuk Mengatasi Stres pada Ibu yang Work From Home (WFH)
Authors: Indrianie Efnie
Published: September 2023

This study aims to determine the effect of Brain Respiration on reducing stress in mothers working from home (WFH). Brain Respiration is a powerful technique to energize the brain because it can regulate emotions that can reduce stress. Fifteen people joined the experimental group and the rest control group. Mothers who were members of the experimental group got Brain Respiration while the control group did not. A biofeedback device measured the degree of stress through electrodermal activity (EDA). The results obtained show that there are differences in the degree of stress in the form of a decrease in the degree of stress in WFH mothers who are included in the experimental group after being given Brain Respiration (T-count = 12, and T-table = 25. If T-count < T-table then H0 rejected). There are also differences in the degree of stress in WFH mothers included in the experimental group and the control group (the results of U-count = 31.5 and U-table = 72). The conclusion can be drawn is that Brain Respiration can reduce stress in WFH mothers.
Faktor-faktor yang Memengaruhi Resiliensi Remaja Pasca Dating Violence: Sebuah Studi Literatur
Authors: Putu Divariani , I Gusti Ayu Putu Wulan Budisetyani
Published: September 2023

Kasus kekerasan dalam hubungan pacaran (dating violence) masih terus terjadi dalam beberapa tahun terakhir. Dating violence di situasi pandemi yang signifikan bagi remaja yang dapat mengarah pada kecemasan maupun depresi, sehingga diperlukannya resiliensi. Proses resiliensi ini dipengaruhi oleh adanya faktor internal dan eskternal remaja selama dan setelah menghadapi dating violence.  Metode pengambilan data dalam tulisan ini menggunakan studi literatur deskriptif pada data sekunder tahun 2016-2021. Hasil tulisan ini diharapkan dapat menjadi acuan bagi usia remaja yang mengalami dating violence agar dapat mengatasi kesulitan yang terjadi dan bangkit dari pengalaman yang terpuruk sehingga mereka mampu menjadi individu yang resilien dan bebas dari permasalahan psikologis di kemudian hari. Hasil studi literatur deskriptif ini menunjukkan bahwa proses resiliensi dipengaruhi oleh adanya faktor internal dan eksternal selama dan setelah terjadinya dating violence pada remaja.
Internet of Things for 4.0 Industry Revolution
Authors: Budiyanto Setiyo , Silalahi Lukman Medriavin
Published: September 2023

In this training, participants were given an understanding of the IoT (Internet of Things) for the Industrial Revolution 4.0 and were accompanied by instructors to get to know the technology. The approach method is based on research results that have been published in electrical engineering. We CO (Collaborated Overseas) with UTHM (Universiti Tun Hussein Onn Malaysia) in the CS (Community Service) programme, with the aim of providing guest lectures on the advancement of IoT technology and IR (Industry Revolution) 4.0. Thus, the contribution to this CS activity is to support the improvement of the quality of skilled labor from partner participants to be in line with industry needs. Therefore, the leadership of the institution approved and held the IoT for 4.0 IR training. Universitas Mercu Buana through the Institute for Research and Community Service participated in the field of ICT (Information and Communication Technology) with the long-term target of developing wireless sensors and actuators, and computing methods in embedded systems and the cloud. The conclusion of this CS activity is that participants were very enthusiastic about this activity and and gained the benefits of science, as well as an understanding of telecommunications.
ÂŞIK VEYSEL’İN ŞİİRLERİNDEN HAREKETLE TÜRK TOPLUM YAPISINDAKİ AHLAKİ ÇÖZÜLME
Authors: BUNSUZ Halil
Published: September 2023

Toplumların ortak paydası olan bazı ögeler vardır. Kültür de toplumların yüzyıllar içerisinde birlikte oluşturdukları ve gelecek nesillere aktardıkları önemli ortak paydalar arasında yer alır. Bir toplumun kültürel varlığının oluşmasında, zenginleşmesinde, büyük kitlelere ulaştırılmasında ve gelecek nesillere aktarılmasında sanatçıların rolü büyüktür. Türk kültürü içerisinde yer alan ve kökleri bilinen en eski zamana kadar ulaşan âşıklık geleneği bahsedilen aşamalarının gerçekleşmesinde önemli bir işlevi yerine getirmiştir. Âşıklık geleneğinin 20. yüzyıldaki son ve güçlü temsilcilerinden olan Âşık Veysel, Türk kültüründe özel bir konuma sahiptir. Çocukluk ve gençlik çağlarında Osmanlı Devleti’nin son dönemlerine şahit olan yaşamının ilerleyen zamanlarında ise cumhuriyetin kurulmasını ve yeni devletin ilk yıllarında kazanılan başarı ve karşılaşılan zorlukları gören Âşık Veysel, şiirleri ile yakın dönem kültürel tarihimiz için önemli bir kaynaktır. Âşıkların tarihin canlı şahidi, toplumların yaygın eğitim ve öğretiminde ikaz edici ve yol gösterici olmaları, nesilden nesile kültür aktarımını sağlamaları, onları kültürel hayatta daha önemli bir konuma getirir. Türk toplumunun 19. ve 20. yüzyılda kültürel anlamda yaşadığı önemli bir dönüşüm vardır. Bu dönüşüm sürecinde Âşık Veysel, Türk toplumunun genel kabul ve değer yargılarını kendi bilgi, birikim ve tecrübesiyle bir değerlendirmeye tabi tutmuş ve estetik bir söyleyişle kaleme almıştır. Okuma yazma bilmemesine rağmen bilge kişiliğiyle kendi süzgecinden geçirdiği değerler arasında ahlak değerleri de bulunmaktadır. Bu çalışmada fütüvvet-nâmelerde sıralanan 49 ahlak değeri Âşık Veysel’in şiirlerinde aranmıştır. Ardından âşığın hangi ahlak değerlerine şiirlerinde dikkat çektiği, eğitsel bir amaçla övdüğü ve özendirdiği tespit edilmiştir. Son olarak çalışmanın asıl amacını oluşturan âşığın şiirlerinden hareketle yaşadığı dönemde bozulan ahlak değerleri ve toplum yapısındaki çözülme/dönüşüm tespit edilmiş ve âşığın bozulan ahlak değerleri karşısında nasıl bir yol izlediği incelenerek ortaya konulmuştur.
Does Pre-Service Elementary Teachers’ Attitude Towards Science Affect Their Science Teaching Efficacy?
Authors: Afifah Nur , Supartinah  , Pujiastuti Pratiwi
Published: September 2023

The Primary School Teacher Education Study Programme is responsible for preparing community members who have academic qualifications and competencies as learning agents. This readiness is the main capital for students to do the work of a teacher. In providing education to students, a teacher should have self-efficacy. This research is a quantitative study with an ex-post facto research type. The objectives of this study determine whether there is an effect of attitudes toward science on the efficacy of teaching science subjects. 147 4th-semester students majoring in Elementary School Teacher Education, Yogyakarta State University, were involved. The data collection technique used a questionnaire using a Dimensions of Attitude Towards Science (DAS) Instrument and The Science Teaching Efficacy Belief Instrument (STEBI-B). The study revealed a significant influence between attitudes toward science and the science teaching efficacy of elementary school teacher education students. The results of the analysis revealed that the coefficient of determination is 0.322, which means that 32.2% of variations in science teaching efficacy can be explained by attitude towards science.
Development of Science Learning Devices Using the Team-Based Learning (TBL) Model with the Assistance of Phet Simulation on The Vibration Concept to Improve Learning Outcomes for Students
Authors: Hali Juliatin P. , Abdjul Tirtawaty , Uloli Ritin
Published: September 2023

Strengthening the 2013 curriculum learning process is carried out through an approach known as a scientific approach that starts with observing, asking, trying, associating and communicating. Through learning activities using a scientific method, one of which is with the help of the Phet simulation, which is expected that students will be able to achieve graduate competency standards. In Team-Based Learning (TBL) learning, the activities carried out by students are mostly used for group activities, such as completing worksheets or tests given by the teacher. One of the assignments or tests is an experiment using a Phet simulation. The results of the activities carried out by the teacher can be used to create more structured groups. The device development model in this study uses the 4-D (four-D) model, which consists of (1) Define, (2) Design, (3) Development, and (4) Disseminate. Based on the results of the research and development of Team-Based Learning devices that have been carried out at SMP Negeri 2 Pulubala, several conclusions can be drawn: Through this research, science learning devices were produced that were valid, practical, and effective. The developed learning device is assessed by a construct validity test with a valid category with minor revisions/slight revisions to fulfil the eligibility validity as a learning device. Likewise, in terms of practicality, team-based learning-problem solving learning devices have met the level of suitability in terms of the implementation of learning and teacher and student response questionnaires. There was a significant change in the average score of students from pretest to posttest in individual and group tests after implementing Team-Based Learning devices. Using Phet simulations as learning media can facilitate the learning process in science learning
Antenatal Education to Support Triple Elimination Program: A Systematic Literature Review
Authors: Sulyastini Ni Komang , Wirawan I Made Ady
Published: September 2023

This study aims to describe cases of transmission of HIV, hepatitis B and syphilis from mother to child and how the role of antenatal education in supporting the triple elimination program. This research was conducted using a systematic literature review approach. Researchers collected data from research articles that have been published in Scopus indexed international electronic journals. Data was collected using several keywords with the Google search engine and portals providing articles from Scopus indexed journals, such as ScienceDirect, MDPI, and NCBI. The data collected was then analyzed by researchers using an interactive data analysis model. The results of the analysis found that the implementation of triple elimination has been successfully carried out in various countries, although there are still various obstacles that must be faced in its implementation. Furthermore, several studies have also found that antenatal education has an important role in reducing the risk of transmission of HIV, hepatitis B and syphilis from mother to child. So, it can be concluded that antenatal education is crucial to provide in order to support the triple elimination program to prevent cases of transmission of HIV, hepatitis B and syphilis from mother to child
Development of STEM-based Science E-Module on the Human Excretory System Topic
Authors: Rungkat Jovialine Albertine , Jeujanan Anggelina , Wola Brian Ricard , Warouw Zusje Wiesje Merry
Published: September 2023

Teachers generally lack sufficient knowledge about STEM approaches, so teachers have difficulty developing STEM-based modules. Our research aims to develop a STEM-based science e-module on the human excretory system topic that is suitable for use by junior high school students. We use a type of research and development (R&D) concerning the Borg & Gall development model modified by Palilingan. Data collection techniques using interviews and questionnaires. The research instruments used interview sheets, product validation questionnaires, and product practicality questionnaires. The results showed that: (1) the validity test by learning media experts obtained a score of 98.33% and was included in the very valid category (no need for revision); (2) the validity test by subject matter experts shows a value of 99.17% and is included in the very valid category (no need for revision); and (3) limited trials in small groups show a value of 93.40% and are included in the very practical category. Based on the research that has been done, the STEM-based science e-module on the human excretory system topic that is suitable for use by junior high school students is appropriate for use by junior high school students.
Mechanism of Salinity Tolerance in Selected Wheat (Triticum aestivum L.) Cultivars
Authors:   Division of Crop Improvement Central Soil Salinity Research Institute, Karnal, Haryana, Singh Dharmendra Singh , K.N Singh ,   Division of Crop Improvement Central Soil Salinity Research Institute, Karnal, Haryana
Published: September 2023

An experiment in NaCl solution culture was conducted to observe the mechanism of salinity tolerance in selected three wheat (Triticum aestivum L.) cultivars, [BWIR7 (Mexico), Gutha (Australian) and KRL19 (Indian)] differing in salinity tolerance. Fifteen days old seedlings of each cultivar grown in half strength Hoagland nutrient solution were subjected to incremental salt stress until the required salinity levels (0, 180-mol m-3) were obtained. Dry matter yield (DMY) at 30 days, indole acetic acid (IAA), abscisic acid (ABA) and total free amino acid (AA) contents of leaves/root at 29 days and dehydrogenase activity of roots at 34 days were determined after initiation of the salinity stress. Shoot and root weight (DMY), dehydrogenase of root and IAA contents both in leaves and root of all the cultivars decreased whereas, ABA and AA contents increased. At saline treatment, cultivar, KRL19 produced maximum shoot DMY and BWIR7 minimum. Whereas, in case of roots Gutha produced maximum and KRL 19 minimum DMY. Dehydrogenase activity of root BWIR7 was more affected followed by Gutha and KRL19. The extent of decrease of IAA content in leaves and roots of Gutha was more pronounced than the other cultivars. Increase in ABA contents of shoots and roots were more in KRL 19 followed by BWIR7 and Gutha respectively. The extent of increase of AA contents was more in the leaves of KRL 19. From this study, it was concluded that cultivar KRL 19 has the salinity inclusion and Gutha salinity exclusion mechanism. The salinity tolerance cultivars were in order of KRL 19 > Gutha> BWIR7
Combining Ability Studies for Quality Traits in Sweet Sorghum (Sorghum bicolor (L.) Moench)
Authors:   Dept of Millets,Centre for Plant Breeding and Genectics,Tamil Nadu Agrl,University Coimbatore 641003, M Indhubala , K Ganesamurthy ,   Dept of Millets,Centre for Plant Breeding and Genectics,Tamil Nadu Agrl,University Coimbatore 641003, D Punitha ,   Dept of Millets,Centre for Plant Breeding and Genectics,Tamil Nadu Agrl,University Coimbatore 641003
Published: September 2023

Combining ability analysis helps in the evaluation of inbreds in terms of their genetic value and in the selection of suitable parents for hybridization. It also helps in the identification of superior cross combinations. In the present study, the general combining ability of the 12 parents and specific combining ability of 35 crosses were estimated through combining ability analysis for yield, yield components and juice quality characters in sweet sorghum using a line x tester mating design. The estimated components of gca and sca variances showed preponderance of non-additive gene action for all the characters studied. This showed the possibilities of improvement of these traits through heterosis breeding. Based on gca effects the lines BJ 3A, CK 60A and AKMS 22A and the testers RSSV 9, SSV 84 and ASV 9401 were good combiners for most of the characters. These parents can be used in pedigree breeding programme for incorporation of desired traits. The hybrid combinations AKMS 22A x RSSV 9, BJ 3A x VMS 98001, BJ 3A x RSSV 9, AKMS14A x RSSV 9 and CK 60 A x VMS 98001 were recorded as the best specific combiners. These hybrids could be exploited for heterosis breeding programme.
Combining Ability in CMS/GMS Based Pigeonpea (Cajanus cajan (L.) Millsp.,) Hybrids
Authors:   Agricultural College and Research Institute,TNAU, Madurai 625 104, D Shoba , A Balan ,   Agricultural College and Research Institute,TNAU, Madurai 625 104
Published: September 2023

Twenty seven hybrids were developed utilizing three lines (two CMS and one GMS) and nine testers and their hybrids were evaluated for ten characters in order to understand the gene action in pigeonpea. The combining ability analysis revealed that variances due to dominance was higher than variances due to additive for all characters indicating the preponderance of non additive gene action governing these traits. Among the lines, MS CO5 and among the testers, CORG 9060, PA 128, CORG 7 and ICPL 83027 were the best general combiners for seed yield. Most of the crosses showing significant sca effects involved one good and one poor or even negative general combiners. The crosses MS CO 5 x CORG 9060, MS CO 5 x PA 128, MS CO5 x CORG 7 , MS CO5 x ICPL 83027 and CORG 990047 A x APK 1 would be suitable for exploiting heterosis for increased pod in pigeonpea.
Gestão das aquisições em um aeroporto público considerando aspectos licitatórios
Authors:   , SALOME OTAVIO AUGUSTO SILVA
Published: September 2023

Os aeroportos são empreendimentos dotados de edifícios, instalações e veículos que permitem o acesso e circulação do público, o transporte de pessoas, bagagens e cargas, e a operação e monitoramento das aeronaves. Portanto, são infraestruturas de extrema importância econômica e que estão sob a constante necessidade de manutenção e projetos de melhoria, além de ser um empreendimento complexo no que tange os aspectos de gerenciamento. Os aeroportos públicos brasileiros estão sujeitos aos instrumentos de planejamento da administração pública, tais como o Plano Plurianual [PPA], a Lei Orçamentária Anual [LOA] e a Lei de Diretrizes Orçamentárias [LDO], bem como fazem a aquisição de produtos e contratação de serviços por meio de licitações. Mudanças na legislação e nos cenários político e econômico afetam diretamente a gestão dos bens públicos e, portanto, impactam a administração destes aeroportos. Neste contexto, o objetivo deste trabalho foi delimitado utilizando as dimensões do Guia PMBOK conciliando suas boas práticas com as leis governamentais. Para tanto, foi estabelecida uma pesquisa documental a partir de dados, documentos, relatórios etc., todos públicos. Ainda, foram avaliadas e apresentadas ferramentas para gestão das aquisições e para gestão de qualidade, explicitando a forma como esses recursos podem contribuir para o auxílio na identificação de possíveis melhorias a serem feitas no decorrer de um projeto em aeroportos da iniciativa pública, não se limitando aos processos licitatórios para aeroportos, e servindo de base para outros projetos de benfeitoria pública, assim maximizando os resultados e a entrega dos pacotes de trabalho dentro da vigência do PPA, acelerando os processos a execução durante a LDO do período, e assim ajustando os custos e os prazos dentro da LDO, assim como se fosse um processo ágil. Fazendo com que os projetos que se iniciem dentro de 4 anos terminem dentro do mesmo do mesmo ciclo do mandato, assim evitando que trocas de governo, terminem ou cortem orçamentos na distribuição de verbas para projetos já iniciados.
Palavras-chave: licitações; INFRAERO; EMAS; ciclo PDCA; leis orçamentárias
Por uma gestão territorial solidária em Igarapé-Açu-PA: contribuições do banco comunitário do Movimento Social Moeda Verde (MMV)
Authors: Mello Mariana Neves Cruz , Lima Andreza Araújo , Magalhães Carolina do Socorro Ferreira
Published: September 2023

O presente artigo aborda a concepção, construção e funcionamento do banco comunitário do Movimento Social Moeda Verde (MMV), no município de Igarapé Açu-PA, que oferta linhas de microcrédito a empreendedores locais, cujo pagamento é realizado por meio de seu equivalente em materiais recicláveis. O Objetivo do artigo é apresentar o processo de criação do banco comunitário, evidenciando as perspectivas e expectativas do MMV para o município de Igarapé-Açu e alguns resultados alcançados. O trabalho foi construído a partir de levantamento bibliográfico sobre economia solidária e banco comunitário, observação participante, relatos de experiência e análise dos relatórios técnicos de avaliação do MMV. A concepção da construção de um banco comunitário vinculado ao MMV nasce no ano de 2021, durante a Pandemia de COVID-19, permitido pela ampla adesão de diversas categoriais sociais e econômicas ao movimento, somados a percepção de uma demanda local por acesso a microcrédito e estímulo ao reestabelecimento dos comércios locais. O banco está em fase de teste até maio de 2022 e oferece linhas de microcréditos pra empreendedores que, ou estão em um nível de endividamento que não conseguem acessar a linhas de crédito tradicionais ou nunca tiveram acesso a elas, como pipoqueiros, vendedores de churros e de batatas fritas.
Evaluation of an Aerial Application of Duet Hd® Against Aedes dorsalis and Culex tarsalis in Rural Habitats of the Great Salt Lake, Utah
Authors: Bibbs Christopher S. , White Gregory S. , Rochlin Ilia , Rivera Andrew , Morris Kattie , Wilson Mackenzie , Schmitz Madeleine , Truttmann Rachel , Dewsnup M. Andrew , Hardman Jason , Salt Quinten , Sorensen R. Bradley , Faraji Ary
Published: September 2023

The Salt Lake City Mosquito Abatement District (SLCMAD) has been conducting aerial applications using an organophosphate insecticide against adult mosquitoes for several decades. In order to evaluate a potential rotation product, aerial applications of Duet HD™, a pyrethroid, were conducted under operational conditions against wild populations of Aedes dorsalis and Culex tarsalis and against colony strains of Cx. pipiens and Cx. quinquefasciatus. The erratic wind patterns of the greater Salt Lake area did not prevent sufficient droplet deposition flux at 9 monitoring locations spread across a 5,120-acre (2,072 ha) spray block within rural habitats. Three separate aerial application trials showed great efficacy against Ae. dorsalis. In contrast, Cx. tarsalis exhibited inconsistent treatment-associated mortalities, suggesting the presence of less susceptible or resistant field populations as a result of spillover from agricultural or residential pyrethroid usage. Bottle bioassays to diagnose pyrethroid resistance using field-collected Cx. tarsalis indicated that some populations of this species, especially those closest to urban edges, failed to show adequate mortality in resistance assays. Despite challenging weather conditions, Duet HD worked reasonably well against susceptible mosquito species, and it may provide a crucial role as an alternative for organophosphate applications within specific and sensitive areas. However, its area-wide adoption into control applications by the SLCMAD could be problematic due to reduced impacts on the most important arboviral vector species, Cx. tarsalis, in this area. This study demonstrates the importance of testing mosquito control products under different operational environments and against potentially resistant mosquito populations by municipal mosquito control districts.
Hemorragia de vías digestivas altas no-varicosa: un acercamiento a pronóstico – Revisión de la literatura
Authors: Frias Ordoñez Juan Sebastian
Published: September 2023

El sangrado gastrointestinal es una emergencia médica y es la causa más frecuente de hospitalizaciones asociado con otras enfermedades a nivel mundial. Representa una entidad con tasa de mortalidad considerable, y se asocia con morbilidad significativa, mortalidad a 30 días y costos para los sistemas de salud. La hemorragia de vías digestivas altas no-varicosa se ha relacionado con factores de riesgo prevenibles, principalmente consumo de alcohol, infección por Helicobacter pylori, y consumo de antiinflamatorios no esteroideos, entre otros. El diagnóstico se confirma con la endoscopia, que también sirve para proporcionar una intervención terapéutica. Esta entidad presenta complicaciones representadas principalmente por resangrado, y muerte. El puntaje de Rockall es la escala pronostica más usada para evaluar el riesgo de complicaciones por hemorragia de vías altas no varicosa. Esta escala ha sido evaluada a nivel mundial en distintos contextos. Mediante el siguiente artículo se plantea revisar el estado del arte enfocado a pronostico para esta entidad en particular.
Colonoscopia en el estudio del dolor abdominal: ¿Vale la pena?
Authors: BarretoNoratto Clara Patricia , Limas Solano Luis Manuel
Published: September 2023

Objetivo: El dolor abdominal es un motivo frecuente de consulta en el paciente ambulatorio y hospitalizado. La colonoscopia es aceptada como el método de elección en el estudio de patologías colónicas como la hematoquecia y la anemia entre otras. Según la Asociación Americana de Endoscopia Gastrointestinal (ASGE), la tasa de colonoscopias no indicadas es del 24,5% para pacientes ambulatorios y del 15,5% para pacientes hospitalizados. El objetivo del presente estudio fue caracterizar los hallazgos e indicación de colonoscopia en el estudio del dolor abdominal en un hospital de III nivel en el periodo comprendido de los meses de noviembre de 2020 a febrero de 2021.

Materiales y métodos: Se realizó un estudio retrospectivo de los pacientes sometidos a colonoscopia por dolor abdominal mediante la revisión de los informes de colonoscopia y la historia clínica electrónica.

Resultados: Se realizaron un total de 209 colonoscopias, de las cuales 60 pacientes presentaban dolor abdominal como motivo de solicitud del procedimiento. El 76,7% de los pacientes fueron derivados desde servicios ambulatorios de otras instituciones prestadoras de salud. El 36,7% tuvieron un resultado normal, el 25% hemorroides, 21,6% diverticulosis sin diverticulitis y 3,3% tumores malignos. La tasa de detección de pólipos en este estudio fue del 10%.

Conclusión: Un tercio de los pacientes con dolor abdominal no tenían una indicación clara del estudio.

Palabras clave: dolor abdominal, colonoscopia, divertículo
Síndrome de “Buried Bumper” resuelto exitosamente usando técnica mixta (Endoscopica- Abierta)
Authors: Puentes Manosalva Fabián
Published: September 2023

El síndrome “buried bumper” (SBB) es una complicación mayor de la gastrostomía endoscópica percutánea (GEP). Es infrecuente y de presentación tardía. Si bien es inusual, cuando se presenta debe ser reconocido de forma precoz, tanto por el médico tratante como por el paciente usuario de GEP y su grupo de soporte, ya que de esto dependerá el éxito en su manejo así como la disminución de complicaciones que podrían ser graves. Se han descrito múltiples técnicas tanto para el diagnóstico como para su resolución. Presentamos un caso que se manejó combinando algunas de esas técnicas descritas y usando los recursos disponibles.
CARACTERIZACIÓN DE QUEMADURAS EN PACIENTES PEDIÁTRICOS DEL HOSPITAL UNIVERSITARIO DE NEIVA COLOMBIA, ENTRE 2015 AL 2019.
Authors: Rodríguez Liévano Angélica Paulette , Veloza Vega Maria Camila , Vega Vega Martha Rocio , Salgado García Doris
Published: September 2023

Objetivo. Describir las características sociodemográficas y clínicas  de los pacientes atendidos en el servicio de pediatría del Hospital Universitario Hernando Moncaleano Perdomo de Neiva (HUHMP), centro de referencia del sur de Colombia, entre enero de 2015 y diciembre de 2019.

Metodología. Estudio observacional, descriptivo, retrospectivo en el cual se incluyeron pacientes menores de 14 años de edad que presentaron quemaduras.

Resultados. Se incluyó un total de 461 pacientes de los cuales, los más afectados se encontraban en el grupo etario de 0-2 años (46.85%). El 84.82% se produjeron  en el hogar, siendo el líquido hirviente (71.37%) la causa más frecuente de quemadura. En términos de severidad,  las quemaduras grado II fueron las más comunes (93.49%)  la mayoría de las cuales  eran menores al <10% de la superficie corporal total (67.03%). Solo se presentó un caso de mortalidad en un paciente con quemaduras grado III, con una extensión mayor del 30 % de la Superficie corporal total (SCT). Se evidenció una asociación estadísticamente significativa entre las variables edad y presencia de complicaciones (p <0.015),  observándose una mayor frecuencia de las mismas en el grupo de preescolares y escolares (56.6%), seguido por los lactantes (35.58%).

Conclusión. Las quemaduras en  la población pediátrica ocurren más frecuentemente en niños de 0  y 2 años siendo  la  quemadura por  líquidos hirvientes, la causa más frecuentemente observada. En la mayoría de los casos la severidad es leve y la estancia hospitalaria es corta.
La inducción de esputo. El arma olvidada en el diagnóstico de la tuberculosis pulmonar
Authors: Hernandez Sebastian
Published: September 2023

La inducción de esputo mediante nebulización de solución salina hipertónica ha sido estudiada por más de 50 años como una herramienta útil y segura en el diagnóstico de la tuberculosis pulmonar [1]. Sin embargo, a pesar de sus beneficios, esta técnica no se ha utilizado de manera generalizada y sistemática en nuestro país. En el contexto actual, donde la tuberculosis sigue siendo un importante problema de salud pública con grandes desafíos en su vigilancia y control, es necesario considerar herramientas costo-efectivas para optimizar el uso de las pruebas diagnósticas disponibles.
APÓSITO DE HIDROFIBRA CON PLATA Vs SULFADIAZINA DE PLATA EN EL TRATAMIENTO LOCAL DE QUEMADURAS DE SEGUNDO GRADO
Authors: Cardenas Zuluada Consuelo
Published: September 2023

El manejo local de las quemaduras debe orientarse a estimular una adecuada cicatrización, al crear un microambiente de la herida que permita cicatrización óptima con mínimo dolor y efectos colaterales; también, disminuir la probabilidad de infección, ocasionar mínimas molestias para el paciente y facilitar el cuidado; sin embargo, no existe un consenso para el tratamiento local óptimo. Objetivo: comparar la sulfadiazina de plata al 1% con el apósito de hidrofibra con plata desde el inicio de su implementación en la institución. Método: se incluyeron historias clínicas de 138 pacientes de 0-18 años con quemadura de segundo grado, menores al 20% de superficie corporal no asociadas a otro tipo de traumas, de enero de 2014 a diciembre de 2017, tiempo en el cual se estaba realizando la implementación de manejo con el apósito de hidrofibra con plata. El 65,2% de los pacientes se manejó con apósito de hidrofibra con plata y el restante 34,8% con sulfadiazina de plata al 1%. Se analizaron las variables sociodemográficas y clínicas. Resultados: se obtuvieron diferencias estadísticamente significativas en cuanto al tiempo de epitelización, el tiempo de utilización de analgésicos, la estancia hospitalaria y los costos, todos a favor de la sulfadiazina de plata. Conclusión: los resultados obtenidos contradicen lo señalado por muchos estudios previamente realizados, lo cual puede deberse a que el tiempo de recolección de la información era el propio de la implementación de una segunda alternativa terapéutica y, por lo tanto, amerita la realización posterior de un ensayo clínico controlado
“Leased” Workers in the EU and in Greece
Authors: Rompoti Eleni D. , Ioannides Alexis D.
Published: September 2023

This article is a literature review on the practice of workers “leased” through Temporary Work Agencies (TWAs). Reference is made to their main features, the institutional framework regarding the protection of these workers as well as the impact that this practice has on the workers. The next section is a presentation of the reasons that lead to the under- or over-estimation of the actual number of workers “leased” through TWAs. The empirical research is presented next, which was conducted about the workers “leased” through TWAS, based on secondary data of the Eurostat’s Labor Force Survey (LFS). The numbers of “leased” workers in the EU-15 during the period of the financial crisis, 2007-2018, is mentioned. The sectors employing the highest numbers of workers “leased” through TWAs and the demographics of the workers are detailed. In addition, two atypical forms of work are described. These two are temporary and part-time employment in the EU-15 during the period of the financial crisis and onwards, based on the most recent data available from Eurostat, from 2007-2022.
Short notes on molecular mechanisms behind antimicrobial drug resistance
Authors: Iftear Kazim Rafi  , Majedul Hoque
Published: September 2023

Infectious disease mortality have occurred often, raising public awareness of their hazards and advancing global antibiotic research. On the other hand, higher antibiotic levels in natural ecosystems are a result of increased antibiotic demand and use. Gene mutations causing antibiotic resistance in bacterial populations were brought on by natural selection and adaption. The emergence of antibiotic-resistant bacteria was caused by the spread of antibiotic resistance genes in ecosystems, which resulted in a number of antibiotic-resistant diseases on a global scale. An overview of the history of antibiotic discovery, antibiotic use, and antibiotic resistance mechanisms is given in this review study. Bioinformatics is also used to combat antibiotic resistance. To control bacteria that no longer respond to the therapy, the creation of new medications appears to be the primary requirement today.
Socialization of Msmes Introduction Electronic Trade
Authors: Aditama Darmawan
Published: September 2023

Village Offense Source is something village Which lie in Subdistrict Benjeng Regency Gresik Province Java East. Administration socialization And application This e-commerce is done to help increase partner sales results. Based on results survey field in village Offense Source there is a number of type MSMEs that is production food, curtains, clothes, service electronic. Almost 80 percent experience constraint in marketing product And service they, Where results sale No maximum Because method marketing Which very limited. Method activity Which used is with use observation directly along approach to para businessmen and do practice application marketing product through electronic commerce. Activity electronic commerce This succeed done with Good, matter This proven with has he made various type media social to para MSMEs Good in form What is it, Instagram, Facebook And etc as media promotion product business them. So that business they Already known wide And naturally increase request.
Environmental Agenda in Russia Since the Beginning of the War
Authors: Davydova Angelina
Published: September 2023

The full-scale war in Ukraine, started by Russia in late February 2022 has both direct and indirect environmental and climate impact. The direct impact usually implies destruction of ecosystems and wildlife, chemical pollution, pollution from the use of warfare and infrastructure destruction. Yet, indirect consequences might have a less obvious effect. From the re-shaping of the global energy, metal, food and fertilizers markets to changes in countries’ environmental and climate policies and actions, the war in Ukraine provokes global change in global and national environmental and climate governance, including Russia’s environmental and climate policies and environmental activism in the country.