bluuebunny/crossref_metadata_2025 huggingface dataset:
Expert perspectives on the changing dynamics of policy advisory systems: the COVID-19 crisis and policy learning in Belgium and Australia
Authors: Easton Marleen , Yarnold Jennifer , Vervaenen Valerie , De Paepe Jasper , Head Brian W.
Published: January 2024

Expert advice played a pivotal role in shaping the COVID-19 policy responses of different countries. Such measures had wide ranging impacts beyond health, including education, economy, law, and other societal aspects. Thus, analysis of how expertise was utilised and adjusted to adapt to changes during the crisis can draw valuable insights into how to better prepare policy advisory systems to respond to future crises. Here we examine the dynamics of COVID-19 policy advisory systems in Belgium and Australia through interviews with 34 experts directly involved during the first two years of the crisis. We examine the temporal changes in how expert advice was sought, provided, and utilised for crisis decision-making, and the various expert groupings and their relationships over time. In both countries, there was policy learning and adjustment, signalled primarily by an expansion in the breadth of perceived relevant expertise as the scope was re-framed from a ‘health’ crisis to an all-encompassing socio-economic crisis. In Australia, policy responses were shaped by a relatively cohesive inter-governmental group of senior health bureaucrats who became gatekeepers of the evidence presented to state and federal government leaders in the National Cabinet. In Belgium, the more fragmented and changing array of advisory groups reflected tensions within crisis management arrangements, resulting in divergent expert opinions both within the formal advisory groups and in the public realm throughout the crisis. Our findings build on the policy advisory systems and policy learning literature and suggest that more adaptive frameworks and principles be developed for specific contexts.
‘We don’t make best use of art in public health’: lessons learned from co-producing a theatre performance to stimulate debate about Universal Credit
Authors: Cheetham Mandy , Vanden Katy , Lindow Laura , Morris Steph , Moffatt Suzanne , McCormick Brad , Wiseman Alice
Published: January 2024

Background:

Universal Credit radically changes the welfare system for working age adults in the UK. Although aiming to simplify the benefit system, its implementation has been widely criticised and the rollout beset with difficulties and delays, negatively affecting the lives of many claimants.

Methods:

Drawing on findings from a qualitative study of Universal Credit claimants and staff supporting them in North East England, we critically reflect on the process of co-producing a play for a public audience with Cap-a-Pie theatre company, artists, public partners, voluntary and community sector organisations and academics.

Reflections and learning:

We draw on reflections from stakeholders involved in the creative process and audience members’ responses to a filmed reading of extracts from the play. We explore the pitfalls, setbacks and successes of co-producing a theatre performance to communicate research findings and inform and enrich public discourse about Universal Credit.

Discussion:

The arts are a vital part of the public health landscape, but the potential utility of theatre remains underexplored as a tool to stimulate debate about the effects of welfare reform. We aim to contribute to debates about the challenges of co-production and social value of using arts-based methods in public health to address inequalities and promote social justice.

Conclusion:

We explore the extent to which collaborations between researchers, public, policy and practice partners, and theatre makers can raise awareness of the effects of Universal Credit, challenge negative attitudes about Universal Credit claimants, and stimulate debate about the adequacy of social security in the UK.
Theorising a spectrum of reasons for failure in knowledge brokering: a developmental evaluation
Authors: MacGregor Stephen
Published: January 2024

Background:

Despite the growing interest in knowledge brokering as an approach to mobilising knowledge for societal benefit, research has only recently begun investigating the consequences of knowledge brokers’ actions. In particular, while it is known that failure can provide a valuable learning experience for individuals and organisations alike, very few studies have explored failure in knowledge brokering.

Aims and objectives:

With the aim of informing how knowledge brokers can navigate common professional challenges, this article discusses a spectrum of reasons for failure in the professional practice of knowledge brokering.

Methods:

Data for this article comes from a developmental evaluation of a network of knowledge brokers, focusing specifically on a set of semi-structured interviews (N = 20).

Findings:

The overarching themes identified in this study are organised according to the three constructs that knowledge brokers act upon in the i-PARIHS framework: innovation, recipients, and context. Knowledge brokers experienced different types of failure across these constructs, ranging from violations of prescribed practices and processes to exploratory testing.

Discussion and conclusions:

Failure is not a monolithic outcome, and future research could seek to identify levers for change regarding the failure experiences available to knowledge brokers. Additionally, it will not be enough to learn to fail; research and practice in knowledge brokering must learn to fail intelligently. Finally, failure cannot remain a private experience. Advancing the field of knowledge brokering will require researchers and practitioners to share when and how their efforts have failed.
A constant learning curve in working towards integrated health policy: twelve years of practical experience at a Dutch municipality
Authors: Mourits Kristine , Fransen Gerdine , Molleman Gerard
Published: January 2024

Background

By establishing and implementing an integrated four-year health policy, Dutch municipalities contribute significantly to the protection and promotion of public health. Scientific literature has many insights into integrated health policy, determinants of health and interventions. How is this knowledge used when determining and shaping an integrated health policy? The authors share their experiences concerning the role of knowledge in: 1) determining policy; 2) integrated collaboration; 3) working towards a healthy living environment; and 4) creating a citywide health movement.

Key points

Based on working on an integrated health policy and the setbacks we have encountered, we have experienced that scientific knowledge and models provide a framework for policy implementation, but other types of knowledge about context, processes and practice are just as important. Furthermore, we learned that other factors are often more decisive in policy and implementation, including the interests of individual parties, correct timing, continuity of persons, and courageous administrators. Working on integrated health policy is a continuous process of staying on course and adapting at the same time, in which searching for the suitable knowledge to work in an evidence-informed way must be part of it.

Conclusion

The greatest challenge when using knowledge in practice lies in expanding the collaboration between researchers, policymakers, professionals and inhabitants, for example by using boundary spanners. The collaboration should aim to organise a long-lasting adaptive collaboration aimed at mutual learning. This should focus on shared discussion of relevant knowledge, with less emphasis on pure acquisition and use of scientific knowledge.
Different Boats, The Same Storm: A Colloquium on Implementing DEI in Challenging Times
Authors: Berman Aliah , Chambers Jason P. , Grow Jean M. , Loebner Josh , McFarlane-Alvarez Susan , Shaw Kristina M. , Thomas Kevin D. , Tsai Wan-Hsiu Sunny , Vega-Centeno Jess A. , Timke Edward
Published: January 2024

Abstract: Advertising & Society Quarterly held its sixth Colloquium on November 3, 2023. During this virtual event, a panel of ten diversity, equity, and inclusion leaders from academia and industry address the complexities of integrating DEI in professional and academic settings. Panelists discuss the backlash to DEI and explore its accompanying causes, such as hyper-politicization, resource constraints, and fear. The participants provide strategies for implementing DEI effectively in both professional and educational settings, advocating for comprehensive approaches that integrate it into organizational values and teaching methods. The discussions highlight the importance of strategic planning, open conversations, and inclusive decision-making to overcome biases, encourage critical thinking, and build empathy. The Colloquium concludes with a Q&A session that delves into strategies to facilitate meaningful and honest conversations about DEI issues.
Calligraphy as a Symbol System
Authors: Ravasio Matteo , Liu Jiachen , Zhu Ye
Published: January 2024

We apply to the art of calligraphy some of the semiotic concepts developed by Nelson Goodman. While this framework cannot describe everything that is interesting and valuable about specific calligraphic traditions, we argue that it can nonetheless elegantly capture some distinctive features of calligraphy and of its position among other major art forms.
The Sanjaya Myth: Sanjaya Belatthiputta and the Catuskoti
Authors: Copeland B. Jack , Alam Nizar Syed Moynul
Published: January 2024

Respected modern scholars regard the pre-Buddhist philosopher Sañjaya Belaṭṭhiputta—a significant figure in the Buddhist canon—as the originator of the important classical argument- forms known as the catuṣkoṭi and catuṣkoṭi vinirmukta. We argue that the early Buddhist texts do not in fact support this view of the origin of these argument-forms; the question of their origin is open. While it is certainly true that the Pāli Sāmaññaphala Sutta and some of its parallels portray Sañjaya as deploying the catuṣkoṭi, there is nothing in these passages to suggest that he was its originator. The situation concerning the catuṣkoṭi vinirmukta is perhaps even more surprising: There is nothing in the early Pāli texts and their parallels—nor in Buddhagosa’s famous Pāli commentary on the early texts—to show that Sañjaya even deployed the catuṣkoṭi vinirmukta let alone originated it. Further, our investigations also call into question the standard portrayal of Sañjaya as an obfuscator and prevaricator. It appears he may have been a more interesting and able philosopher than the Sāmaññaphala Sutta—and modern accounts based on it—maintain.
Doing Politics with Animals
Authors: Donaldson Sue , Kymlicka Will
Published: January 2024

Abstract: An increasing number of theorists are challenging the idea that only humans can engage in politics and propose that humans must learn how to do politics with animals. But what does it mean to do politics with animals? We consider several recent developments at the frontiers of social inquiry that are relevant, including (1) proposals for the institutional representation of animals’ interests in human political decision-making processes; (2) growing ethological evidence for animals’ own capacities for language, culture, and collective decision-making; and (3) new theoretical accounts of political agency and community that emphasize its embodied, emplaced, and interdependent nature. Each illuminates potential futures for animal politics and for just human-animal relations.
The Future of the Mnemonic Turn
Authors: Olick Jeffrey K.
Published: January 2024

Abstract: Observing the efflorescence of scholarly and public discourse about memory and commemoration since about the 1970s, historians and others have expressed concerns about “the memory boom” and “the memory industry.” Referring instead, and less negatively, to “the mnemonic turn,” this article responds to those concerns. It shows that many critiques were based on a Manichean distinction between “history” and “memory”—and between “historiography” and “memory studies”—that led to faulty predictions about the future of scholarly and public interest in memory. It makes a strong case for a robust memory studies that seeks not to displace historical truth-telling but to work alongside it to understand when, where, and how historiography might or might not be an effective response to problematic memory politics and practices.
From Holocaust Studies to Atrocity Prevention: Genocide Studies and the Growth of Transdisciplinary Activist Scholarship
Authors: Whigham Kerry
Published: January 2024

Abstract: This article examines the transdisciplinary, activist impulse in genocide scholarship by exploring several debates that have shaped and are shaping the field, along with their implications. Although the field of genocide studies certainly includes a number of scholars who are not concerned directly with the question of prevention, this article focuses on several ontological and epistemological debates regarding how genocide scholarship can contribute to prevention. The first debate concerns the question of what the field is actually studying. The second set of debates centers on how to study genocide and its prevention. These include debates on the methodological frictions that exist between focusing on the global, national, and local, as well as between a reliance on quantitative and qualitative research in the field.
Cross-phase modulation in two-dimensional spectroscopy
Authors: Cai Mao-Rui , Zhang Xue , Cheng Zi-Qian , Yan Teng-Fei , Dong Hui
Published: January 2024

Developing from transient absorption (TA) spectroscopy, two-dimensional (2D) spectroscopy with pump-probe geometry has emerged as a versatile approach for alleviating the difficulty in implementing 2D spectroscopy with other geometries. However, the presence of cross-phase modulation (XPM) in TA spectroscopy introduces significant spectral distortions, particularly when the pump and probe pulses overlap. We demonstrate that this phenomenon is extended to the 2D spectroscopy with pump-probe geometry and the XPM is induced by the interference of the two pump pulses. We present the oscillatory behavior of XPM in the 2D spectrum and its displacement with respect to the waiting time delay through both experimental measurements and numerical simulations. Additionally, we explore the influence of probe pulse chirp on XPM and discover that by compressing the chirp, the impact of XPM on the desired signal can be reduced.
Design of ultra-wide-field scanning laser fundus imaging system with cascaded conicoid mirrors
Authors: Jiang Huilv , Zhao Zengwei , Yuan Quan , Ma Ke , Li Yiyu
Published: January 2024

We propose and design a multi-stage cascaded scanning laser ophthalmoscope (SLO) for ultra-wide field (UWF), which uses conicoid mirrors, constructed by conjugation of pupil plane. The vergence uniformity and the angular magnification of a cascaded conicoid mirrors (CCM) system are analyzed recursively and optimized preliminarily to achieve high quality imaging with UWF, and the optimal system with the model eye are obtained by simulation and optimization. Two-stage and three-stage cascaded systems are designed with this method, and the formulas of beam vergence and angular magnification are obtained by theoretical derivation. As compared to the two-stage CCM system, the proposed three-stage cascaded UWF SLO has superior performance in imaging quality. Its average RMS radius of spot diagram is calculated to be 26.372 µm, close to the diffractive limit resolution. The image resolution of human retina can be up to 30 µm with 135° FOV in theory. The three-stage cascaded SLO is more suitable for UWF fundus imaging. This study will be helpful for early screening and accurate diagnosis of various diseases in the peripheral retina.
Perimeter monitoring of urban buried pipeline threated by construction activities based on distributed fiber optic sensing and real-time object detection
Authors: Li Suzhen , Peng Renzhu , Liu Zelong , Liu Xuqiang
Published: January 2024

Urban construction activities seriously jeopardize the security of buried pipeline. Distributed optical fiber vibration monitoring is one of the most promising ways to prevent third-party threats, of which the biggest challenge is to quickly and accurately detect rare abnormal events from extremely large amounts of time-space raw data. By analogy with image recognition, the task here is similar to object detection if considering the time-space optical signals as the grayscale images and the abnormal events as the objects. Given this, what we believe to be a novel monitoring method is proposed, which consists of two Faster R-CNN models, a max pooling layer and a monitoring strategy. In the field tests, the 86-hour optical vibration signals for 5.25 km distance are recognized within 6.6 minutes with the recognition rate of 98.85% for construction activities, and only two false alarms are issued. The proposed method can reduce the recognition time by 99.59% compared to the CNN-based method.
Hollow metal tubes for efficient electron manipulation using terahertz surface waves
Authors: Yu Xieqiu , Zeng Yushan , Bai Yafeng , Song Liwei , Tian Ye
Published: January 2024

Compact electron sources have been instrumental in multidiscipline sciences including fundamental physics, oncology treatments, and advanced industries. Of particular interest is the terahertz-driven electron manipulation that holds great promise for an efficient high gradient of multi-GeV/m inside a regular dielectric-lined waveguide (DLW). The recent study relying on terahertz surface waves has demonstrated both high terahertz energy and improved coupling efficiency with the DLW. However, the large energy spread pertaining to the laser-induced electron pulse impedes the practical use of the system. Here, we propose a scheme for extending the idea of surface-wave-driven electron manipulation to mature electron sources such as commercial direct-current and radio-frequency electron guns. By using a simple hollow cylinder tube for electron transmission, we show that the electron energy modulation can reach up to 860 keV, or compress the electron pulse width to 15 fs using a 2.9 mJ single-cycle terahertz pulse. The trafficability of the hollow tube also allows for a cascade of the system, which is expected to pave the way for compact and highly efficient THz-driven electron sources
Modulation of photonic skyrmions in a thin metal film structure
Authors: Zhang Yi-Chen , Zhao Li-Ming , Zhou Yun-Song
Published: January 2024

Photonic skyrmions have been a hot topic in recent years. However, modulating the spin distributions of the skyrmions is still a challenging topic. In this paper, we investigate the detailed spin distributions of photonic skyrmions in thin metal film sandwiched by different dielectrics. We find that the ratios of different spin components can be adjusted by the thickness of the metal film, while the absolute value of total spin can be controlled by the frequency of the light source. Therefore, by choosing proper metal thickness in the preparation process and certain beam frequency in actual experiment, we can get the exact type of spin distribution we prefer. In addition, when the dielectric layers are arranged asymmetrically, the spin distributions can also be modulated significantly by adjustig the ratio of the dielectric constants of the upper and lower dielectric layers. Our results provide a new pathway for the modulation of photonic skyrmions.
Circular-target-style bifocal zoom metalens
Authors: Zhao Yongmin , Liu Fengfeng , Sui Zhanpeng , Kong Chi , Dai Shige , Lin Yu , Zeng Zhongming , Jiang Chunping
Published: January 2024

Optical zoom plays an important role in realizing high-quality image magnification, especially in photography, telescopes, microscopes, etc. Compared to traditional bulky zoom lenses, the high versatility and flexibility of metalens design provide opportunities for modern electronic and photonic systems with demands for miniature and lightweight optical zoom. Here, we propose an ultra-thin, lightweight and compact bifocal zoom metalens, which consists of a conventional circular sub-aperture and a sparse annular sub-aperture with different focal lengths. The imaging resolutions of such single zoom metalens with 164 lp/mm and 117 lp/mm at magnifications of 1× and 2× have been numerically and experimentally demonstrated, respectively. Furthermore, clear zoom images of a dragonfly wing pattern have been also achieved using this zoom metalens, showing its distinctive aspect in biological imaging. Our results provide an approach for potential applications in integrated optical systems, miniaturized imaging devices, and wearable devices.
Electrodynamic modeling of threshold-free lasing in photonic time crystals
Authors: Xu Ke , Fang Ming , Fen Jian , Wang Chao , Xie Guoda , Huang Zhixiang
Published: January 2024

An electrodynamic model is presented in this Letter to describe thresholdless lasers, utilizing the application of photonic time crystals (PTCs). By integrating the distinctive physical properties of PTCs and employing a comprehensive model based on a four-level system, the feasibility of achieving thresholdless laser operation is demonstrated. The proposed electrodynamic model comprehensively captures the intricate interplay between the electromagnetic field and the PTC medium. The model takes into account the ultrafast periodic variations in the refractive index of the PTCs, which arise from their time crystal-like behavior. Additionally, the dynamic response of the four-level system is considered, factoring in the processes of population inversion and relaxation. This Letter seeks to elucidate the underlying mechanisms that facilitate thresholdless laser operation in PTC-based systems. Through our electrodynamic modeling approach, we demonstrate that the ultrafast variations in the refractive index of PTCs give rise to a self-sustaining laser action, obviating the need for a lasing threshold. Moreover, we investigate the impact of various parameters, including pump power and modulation period, on the laser’s performance and output characteristics. The developed electrodynamic model provides a comprehensive framework for comprehending and designing thresholdless lasers based on photonic time crystals. This research contributes to the advancement of thresholdless laser technology and opens up possibilities for applications in optical communications, sensing, and quantum photonics.
Experimental demonstration of quantum-inspired optical symmetric hypothesis testing
Authors: Wadood S. A. , Sethuraj K. R. , Liang Kevin , Grace Michael R. , La Rue Gavin , Guha Saikat , Vamivakas A. N.
Published: January 2024

We use a phase-sensitive measurement to perform a binary hypothesis testing, i.e., distinguish between one on-axis and two symmetrically displaced Gaussian point spread functions. In the sub-Rayleigh regime, we measure a total error rate lower than allowed by direct imaging. Our results experimentally demonstrate that linear-optical spatial mode transformations can provide useful advantages for object detection compared with conventional measurements, even in the presence of realistic experimental cross talk, paving the way for meaningful improvements in identifying, detecting, and monitoring real-world, diffraction-limited scenes.
High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes
Authors: Heidarian Sheida , Guliaev Andrei , Nicoloff Hervé , Hjort Karin , Andersson Dan I.
Published: January 2024

Heteroresistance (HR) is an enigmatic phenotype where, in a main population of susceptible cells, small subpopulations of resistant cells exist. This is a cause for concern, as this small subpopulation is difficult to detect by standard antibiotic susceptibility tests, and upon antibiotic exposure the resistant subpopulation may increase in frequency and potentially lead to treatment complications or failure. Here, we determined the prevalence and mechanisms of HR for 40 clinical Staphylococcus aureus isolates, against 6 clinically important antibiotics: daptomycin, gentamicin, linezolid, oxacillin, teicoplanin, and vancomycin. High frequencies of HR were observed for gentamicin (69.2%), oxacillin (27%), daptomycin (25.6%), and teicoplanin (15.4%) while none of the isolates showed HR toward linezolid or vancomycin. Point mutations in various chromosomal core genes, including those involved in membrane and peptidoglycan/teichoic acid biosynthesis and transport, tRNA charging, menaquinone and chorismite biosynthesis and cyclic-di-AMP biosynthesis, were the mechanisms responsible for generating the resistant subpopulations. This finding is in contrast to gram-negative bacteria, where increased copy number of bona fide resistance genes via tandem gene amplification is the most prevalent mechanism. This difference can be explained by the observation that S. aureus has a low content of resistance genes and absence of the repeat sequences that allow tandem gene amplification of these genes as compared to gram-negative species.
Wildlife vaccination strategies for eliminating bovine tuberculosis in white-tailed deer populations
Authors: Pandey Aakash , Feuka Abigail B. , Cosgrove Melinda , Moriarty Megan , Duffiney Anthony , VerCauteren Kurt C. , Campa Henry , Pepin Kim M.
Published: January 2024

Many pathogens of humans and livestock also infect wildlife that can act as a reservoir and challenge disease control or elimination. Efficient and effective prioritization of research and management actions requires an understanding of the potential for new tools to improve elimination probability with feasible deployment strategies that can be implemented at scale. Wildlife vaccination is gaining interest as a tool for managing several wildlife diseases. To evaluate the effect of vaccinating white-tailed deer (Odocoileus virginianus), in combination with harvest, in reducing and eliminating bovine tuberculosis from deer populations in Michigan, we developed a mechanistic age-structured disease transmission model for bovine tuberculosis with integrated disease management. We evaluated the impact of pulse vaccination across a range of vaccine properties. Pulse vaccination was effective for reducing disease prevalence rapidly with even low (30%) to moderate (60%) vaccine coverage of the susceptible and exposed deer population and was further improved when combined with increased harvest. The impact of increased harvest depended on the relative strength of transmission modes, i.e., direct vs indirect transmission. Vaccine coverage and efficacy were the most important vaccine properties for reducing and eliminating disease from the local population. By fitting the model to the core endemic area of bovine tuberculosis in Michigan, USA, we identified feasible integrated management strategies involving vaccination and increased harvest that reduced disease prevalence in free-ranging deer. Few scenarios led to disease elimination due to the chronic nature of bovine tuberculosis. A long-term commitment to regular vaccination campaigns, and further research on increasing vaccines efficacy and uptake rate in free-ranging deer are important for disease management.
Impact of higher-income countries on child health in lower-income countries from a climate change perspective. A case study of the UK and Malawi
Authors: Hannah Eilish , Etter-Phoya Rachel , Lopez Marisol , Hall Stephen , O’Hare Bernadette
Published: January 2024

Climate change is the number one threat to child health according to the World Health Organisation. It increases existing inequalities, and lower-income countries are disproportionately affected. This is unjust. Higher-income countries have contributed and continue to contribute more to climate change than lower-income countries. This has been recognised by the United Nations Committee on the Rights of the Child, which has ruled that states can be held responsible if their carbon emissions harm child rights both within and outside their jurisdiction. Nevertheless, there are few analyses of the bilateral relationship between higher- and lower-income countries concerning climate change. This article uses the UK and Malawi as a case study to illustrate higher-income countries’ impact on child health in lower-income countries. It aims to assist higher-income countries in developing more targeted policies. Children in Malawi can expect more food insecurity and reduced access to clean water, sanitation, and education. They will be more exposed to heat stress, droughts, floods, air pollution and life-threatening diseases, such as malaria. In 2019, 5,000 Malawian children died from air pollution (17% of under-five deaths). The UK needs to pay its ‘fair share’ of climate finance and ensure adaptation is prioritised for lower-income countries. It can advocate for more equitable and transparent allocation of climate finance to support the most vulnerable countries. Additionally, the UK can act domestically to curtail revenue losses in Malawi and other lower-income countries, which would free up resources for adaptation. In terms of mitigation, the UK must increase its nationally determined commitments by 58% to reach net zero and include overseas emissions. Land use, heating systems and renewable energy must be reviewed. It must mandate comprehensive scope three emission reporting for companies to include impacts along their value chain, and support businesses, multinational corporations, and banks to reach net zero.
Budget impact analysis of venetoclax for the management of acute myeloid leukemia from the perspective of the social security and the private sector in Argentina
Authors: Palacios Alfredo , Espinola Natalia , Gonzalez Juan Martin , Rojas-Roque Carlos , Rivas Maria Marta , Kanevski Diego , Morisset Pierre , Augustovski Federico , Pichon-Riviere Andres , Bardach Ariel
Published: January 2024

Objective

This study aimed to estimate the budget impact of the incorporation of venetoclax for the treatment of patients with Acute Myeloid Leukemia (AML) over 75 years of age or those with comorbidities and contraindications for the use of intensive chemotherapy, from the perspective of the social security and the private third-party payers in Argentina.

Methods

A budget impact model was adapted to estimate the cost difference between the current scenario (azacitidine, decitabine and low doses of cytarabine) and the new scenario (incorporation of venetoclax) for a third-party payer over a time horizon of three years. Input parameters were obtained from a literature review, validated or complemented by expert opinion using a modified Panel Delphi approach. All direct medical costs were estimated by the micro-costing approach and were expressed in US dollars (USD) as of September 2020 (1 USD = 76.18 Argentine pesos).

Results

For a third-party payer with a cohort of 1,000,000 individuals covered, incorporating venetoclax was associated with an average budget impact per-member per-month (PMPM) of $0.11 USD for the social security sector and $0.07 USD for the private sector. The duration of treatment with venetoclax was the most influential parameter in the budget impact results.

Conclusion

The introduction of venetoclax was associated with a positive and slight budget impact. These findings are informative to support policy decisions aimed to expand the current treatment landscape of AML.
Avaliação do Sistema de Tratamento de Esgotos Navegantes – Rio Grande (RS)
Authors: Souza José Francisco Almeida de , Silva Carla Silva da , Dutra Tuane de Oliveira , Brum Marília de Marco
Published: January 2024

Neste artigo é feita a avaliação do desempenho de uma estação de tratamento de esgotos (ETE) e da influência do lançamento de seu efluente na qualidade da água de um arroio local, baseada em dados operacionais, relativos ao ano de 2019, fornecidos pela CORSAN. Para avaliar a eficiência da ETE foram analisados os parâmetros demanda bioquímica de oxigênio, sólidos suspensos totais, demanda química de oxigênio, nitrogênio amoniacal, fósforo total, Escherichia Coli e Sólidos sedimentáveis. No corpo receptor forram analisados também o oxigênio dissolvido e pH. O sistema foi muito eficiente na remoção de DBO, mas a eficiência na remoção de nutrientes foi baixa. Foi realizado um balanço de massa para OD, o qual mostrou que no período de avaliação a vazão do arroio Martins variou entre 2.163,1 m3.d-1 e 80.921,2 m3.d-1, com média de 30.860,0 m3.d-1.
External Factors of Business Environment and Family Business: Theoretical Review
Authors: Svilane Ina , Kalkis Henrijs
Published: January 2024

The study examines contemporary theories of the business environment and family entrepreneurship and shows what external effects the business environment has and what impact it can have on family businesses. Theories outlining the main external factors of the business environment and the different aspects of family businesses are highlighted. The business environment theories of Professors Campbell D. J. & Craig T. provide, in our opinion, the most comprehensive insight into the analysis of the external factors of the business environment, while Professors T. Zellwegers, K. E. Gersick and St. R. Covey highlight the various dimensions of the family business and its operational organisation. Our task in this article is to examine these two areas and how they interact and influence each other. The viability of family businesses requires stability and security and is determined by the environment in which the business operates. The external factors of the business environment are mostly those that the company cannot influence and that lead to uncertainty and instability. Early identification of undesirable conditions can help family businesses to respond more quickly. The European Commission's definition of a family business is at odds with that of academics. With this study, we invite you to update the discussion on the modern legal definition of a family business, which is the basis for policy planning documents, ensuring legal protection, assumption or inheritance of liabilities, etc. The results of the study could be significant for researchers dealing with business and economic regularity, as well as for entrepreneurs and professionals whose field of activity is related to business or public administration.
How Innovation Plays a Role in Banking and Increases Profitability
Authors: Phanum Umbaruk Kieta
Published: January 2024

Banking as an extensive information subject is constantly changing under the marketing influences of the era of huge information. Checking out the revolutionary important specifics analytic sources, as Data Mining techniques are essential for the banking business. This aims to reveal valuable information from the vast length of info and realize far better strategic management in addition to client pleasure. To provide decent assistance for future research and development, a most thorough present analysis of the existing study problem of DM in banking will be unbelievably beneficial. Since pre existing ratings just tackle the applications until 2013, this specific newspaper seeks to run this specific exploration gap, and also supplies the sizable progressions and most current DM implementations in banking document 2013. By collecting and analyzing the fads of review concentration, info online resources, specialized aids, and info analytical online resources, this specific newspaper helps obtain important insights about the succeeding developments of equally DM together with the banking business, in addition to a comprehensive one stop guide table. Furthermore, we recognize the main obstacles and also provide a summary for all those interested in big data.
LIQUID-SOLID COUPLING RESPONSE OF SURROUNDING ROCK MASS OF LARGE-DIAMETER RIVER-CROSSING SHIELD TUNNEL
Authors: Zhang Shanglong , Cheng Xuansheng , Li Xiaoshuang , Qi Lei
Published: January 2024

The purpose is to investigate the response of seepage field, displacement field and stress field in the surrounding rock mass during dynamic tunneling in soft soil area. Relied on a large-diameter river-crossing shield tunnel project, considering driving force, shield tail grouting pressure, and the friction resistance between the shield shell and the soil, a three-dimensional fine tunnel model considering the liquid-solid coupling effect in the soil during dynamic tunneling was established by employing the finite difference method. The response characteristics of pore water pressure, displacement and stress in the surrounding rock mass were obtained. The results show that during shield tunneling and shield tail grouting, the pore water pressure in the range of 0.5 times the hole diameter around the tunnel decreases and increases respectively due to the liquid-solid coupling in the surrounding rock mass. When the shield tunneling moves away, the pore water pressure of the soil near the vault decreases, and the pore water pressure near the tunnel arch bottom increases. The impact range of shield tail grouting on the vertical settlement of the upper soil is about 0.5 times the hole diameter. The shield tail grouting can effectively reduce the vertical settlement of the top soil and slow down the vertical uplift of the bottom soil. During shield tunneling the vertical stress distribution of the soil above the vault of the working position and around the excavation surface is funnel-shaped, and the vertical stress around the excavated tunnel decreases.
People Tracking in Video Surveillance Systems Based on Artificial Intelligence
Authors: Nasry Abir , Ezzahout Abderrahmane , Omary Fouzia
Published: January 2024

As security is one of the basic human needs, we need security systems that can prevent crimes from happening. In general, surveillance videos are used to observe the environment and human behavior in a given location. However, surveillance videos can only be used to record images or videos, without additional information. Therefore, more advanced cameras to obtain other additional information such as the position and movement of people. This research extracted this information from surveillance video footage using a person tracking, detection and identification algorithm. The framework for these is based on deep learning algorithms, a popular branch of artificial intelligence. In the field of video surveillance, a person tracking is considered a challenging task. Many computer vision, machine learning and deep learning techniques have been developed in recent years. The majority of these techniques are based on frontal view images or video sequences. In this work, we will compare some previous work related to the same topic.
Räume kultureller Demokratie im Kontext der Klimakrise. Überlegungen zu Experimentierräumen an der Schnittstelle von Kunst, Vermittlung und Forschung
Authors: Zobl Elke
Published: January 2024

Elke Zobl widmet sich in diesem Beitrag der Frage, wie künstlerische Experimentierräume im öffentlichen Raum im Zusammenspiel mit dem Konzept der cultural democracy geschaffen werden und welche Möglichkeiten, Ambivalenzen und Herausforderungen für die Kulturvermittlung sowie künstlerische und kulturelle Praktiken entstehen können. Sie bezieht sich auf Erfahrungen des Forschungsprojekts »Räume kultureller Demokratie« mit einem Schwerpunkt auf die Klimakrise. Nach einer Diskussion von Prozessen und Ergebnissen in der Umsetzung der "Pop-Up-Erzähllabore" schließt Zobl mit Überlegungen wie im Rahmen künstlerischer Arbeitsprozesse in konkreten Situationen Räume kultureller Demokratie eröffnet werden können und was dies für eine gesellschaftliche Wissensvermittlung und die kritisch-engagierte Ausrichtung von Forschung bedeutet.
Kunstvermittlung als ›close looking‹. Eine kulturwissenschaftliche Blicklehre
Authors: Hammer-Tugendhat Daniela
Published: January 2024

Daniela Hammer-Tugendhat widmet sich in diesem Beitrag der Bedeutung genauer Bildanalysen. Exemplarisch zeigt sie an Bildern der Frühen Neuzeit ihr methodisches Herangehen: Analyse der ästhetischen Struktur, Kontextualisierung in der Bildtradition und den Diskursen und gesellschaftlichen Praxen der Zeit, Verhältnis von bildlicher Inszenierung/Motiv und von Text und Bild, das Verhältnis von Kunst und Wissenschaft und von Kunst und Politik. Gezeigt wird, dass und wie Bilder Bedeutung produzieren und dadurch dazu beitragen, wie wir 'Wirklichkeit' erfassen.
Russischer Krieg gegen die Ukraine: Bleiben oder fliehen?
Authors: Voznyuk Olha
Published: January 2024

Olha Voznyuk widmet sich in diesem Beitrag dem Problem der Existenz und Herausforderungen der ukrainischen Wissenschaft in der Zeit des russischen Krieges gegen die Ukraine. Die Autorin analysiert die aktuelle Lage der wissenschaftlichen Institutionen in der Ukraine, die Zerstörung der Universitäten und die Tragödie der ukrainischen Wissenschaftler*innen, die während der Militäroperationen und der russischen Raketenangriffe auf ukrainische Gebiete zwischen beruflicher Entwicklung und persönlicher Sicherheit wählen müssen.
Humanidades digitais e estudos históricos do léxico
Authors: Finatto Maria José Bocorny
Published: January 2024

No contexto desenhado por uma nova transdisciplina (GOLUB, LIU, 2021) denominada Humanidades Digitais (DH), como linguistas, situamos o desafio de extrair dados e conhecimentos dispersos a partir de arquivos digitais que trazem registros de língua escrita ou falada. Já em meio a esse cenário ou um tanto distante dele, na área de Letras, temos toda uma tradição de trabalhos linguísticos, lexicológicos, lexicográficos e afins dedicados a estudar documentos escritos antigos, impressos e manuscritos. A antiguidade dessas fontes, naturalmente, é sempre uma condição relativa. As DH têm se situado na interseção da Computação e das Humanidades. E, ao lidar com dados digitais em cronologias, envolvem pesquisa trans- e multidisciplinar colaborativa, reunindo especialmente historiadores e documentalistas, trazendo ferramentas e métodos digitais para o estudo das Humanidades e dos patrimônios históricos resguardados em formatos on-line. As DH dialogam com novas formas de ensino e pesquisa, nas suas realidades presenciais, remotas e on-line, ao mesmo tempo em que criticam como novos formatos e modalidades impactam o patrimônio cultural e a cultura digital. Assim, as DH compõem importante campo de pesquisa em crescimento. Um campo para o qual os estudos da linguagem e as Ciências do Léxico, especialmente se conjugados com as tecnologias do Processamento de Linguagem Natural (PLN) e da Linguística de Corpus, têm muito a oferecer. Afinal, existem muitas técnicas de pesquisa linguística, feitas com algum apoio computacional, que podem fornecer ajuda útil para o estudo de textos históricos, de literaturas e de qualquer outro discurso humano que esteja sob investigação nessas condições.
Um ministro, um ministério e o discurso desconcertado
Authors: Silva Flávia Junqueira da , Silva Lazara Cristina da
Published: January 2024

Este artigo realiza uma análise da fala Ministro da Educação Milton Ribeiro no Programa Novo Sem Censura da TV Brasil sobre o contexto da Educação Especial e o público desta modalidade de ensino. É de abordagem qualitativa e tem por objetivo problematizar o contexto da Educação Especial nos rumos direcionados pelas políticas de inclusão com análise crítica baseada nos estudos Foucaultianos. Constatamos que os estudantes com deficiência, vivenciam um processo de in/exclusão nos debates discursivos de políticas para o seu governo, políticas sustentadas pelos interesses neoliberais. Pretende pensar e refletir a partir da crítica do que é dado como imperativo de Estado no discurso da inclusão no âmbito do neoliberalismo.
Planos de desenvolvimento institucional: um diálogo com a inclusão educacional de pessoas com deficiência
Authors: Carneiro Tatiana Rodrigues , Molina Karina Soledad Maldonado
Published: January 2024

Esta pesquisa objetivou analisar os PDIs de 10 Instituições de Ensino Públicas Brasileiras, com IGC na faixa 5, a fim de verificar o processo de inclusão educacional de alunos com deficiência. O PDI é um dos mais importantes documentos das Instituições de Ensino Superior. Esse documento apresenta a IES e suas políticas, constituindo-se em uma ferramenta de gestão. A partir de uma análise de cunho descritivo documental constatou-se que ainda temos IES públicas que sequer contemplam os alunos com deficiência em seus processos de seleção e que embora esforços sejam realizados no sentido de promover acessibilidade, ainda se tem um longo caminho para que a universidade pública brasileira esteja preparada para educar a todos e que reconheça que a inclusão é um direito e não um ato assistencial.
Acesso e permanência de pessoas com deficiência no ensino superior: participação na academia científica como forma de ativismo político
Authors: Paiva Juliana Cavalcante Marinho , Gesser Marivete
Published: January 2024

A educação brasileira para estudantes com deficiência foi marcada por processos de exclusão pautados em modelos estigmatizantes de compreensão da deficiência. O objetivo desta pesquisa foi analisar os discursos de pessoas com deficiência acerca do seu acesso e permanência ao ensino superior. Foi uma pesquisa de abordagem qualitativa. As informações foram obtidas por meio de entrevistas narrativas com 16 participantes e diário de campo e analisadas a partir da análise de discurso na perspectiva da psicologia histórico-cultural. Os resultados apontam para a presença de barreiras no acesso e permanência na graduação e especialmente na pós-graduação e para a intersecção da deficiência com raça e classe como um importante elemento a ser considerado pelas políticas públicas de inclusão.
Acesso de acadêmicos/as com deficiência ao ensino remoto na pandemia: das políticas às práticas
Authors: Sganzerla Gabriela de Moraes , Digiovanni Alayde Maria Pinto
Published: January 2024

Esta pesquisa objetiva analisar como o contexto da pandemia afetou estudantes com deficiência em uma universidade pública do interior do Paraná. Para tanto, exploramos as políticas públicas e documentos elaborados sobre ensino remoto em nível local, estadual e nacional. Tomamos como referencial a perspectiva teórico-metodológica da Psicologia Histórico-Cultural. A coleta de dados deu-se nas etapas de levantamento de documentos e na pesquisa de campo, com entrevistas a acadêmicos/as com deficiência e a gestores/as responsáveis pelas políticas de inclusão da universidade. Conclui-se que se produziu poucos recursos para amparar as pessoas com deficiência durante o ensino remoto na pandemia, de maneira que os/as discentes precisaram, de forma autônoma, desenvolver estratégias de estudo a fim de superar as adversidades do contexto.
Acessibilidade nas Instituições Federais de Educação Superior: uma revisão sistemática
Authors: Picharillo Alessandra Daniele Messali , Costa Ailton Barcelos da , Elias Nassim Chamel
Published: January 2024

Este trabalho teve o objetivo de identificar o que a literatura tem apresentado sobre acessibilidade em Instituições Federais de Ensino Superior (Ifes) e discutir esses dados com a legislação federal vigente. Foi realizada uma na base “Periódicos Capes”, resultando em um banco final de dez artigos. A partir dos estudos selecionados, pode-se concluir que ainda existe muito a ser feito, apesar dos avanços consideráveis na legislação nos últimos anos. Os resultados mostram que ainda existem problemas em relação à acessibilidade arquitetônica nas Ifes, mesmo esta dimensão sendo uma das mais evidenciadas nos estudos. Além disso, a acessibilidade atitudinal continua sendo um dos maiores desafios, requerendo formação e conscientização de toda a comunidade universitária. A fragilidade encontrada na acessibilidade atitudinal pode dificultar o reconhecimento amplo do direito à educação de todos os estudantes, conforme garantido pela legislação, entravando ou não promovendo ações que ampliem a remoção de barreiras no Ensino Superior.