bluuebunny/crossref_metadata_2025 huggingface dataset:
Ultrafiltration Patterns during Automated Peritoneal Dialysis: Findings and Insights to Peritoneal Physiology
Authors: El Shamy Osama , Wyatt Nicole , Patel Sagar , Abudaff Naief , Greevy Robert , Guide Andrew , Shah Ankur D. , Arroyo Juan Pablo , Golper Thomas A.
Published: July 2024

Key Points

There is a consistent increase in ultrafiltration volumes achieved per cycle over the course of an automated peritoneal dialysis treatment session.

A better understanding of intercycle ultrafiltration trends may inform prescription interventions that can improve patient retention.

Surface area recruitment, mesenteric elasticity, and cumulative glucose concentration in the interstitium are possible explanations for our findings.

Background

With the growing use of automated peritoneal dialysis (APD), it is important to improve our knowledge of the clinical patterns and physiology of APD treatment sessions. The ultrafiltration (UF) achieved during each cycle of an APD treatment is assumed to be relatively linear if the delivered prescription is the same. We set out to determine whether that is indeed the case.

Methods

This is a single-center, cross-sectional study of patients on prevalent peritoneal dialysis (PD). All adult patients on APD (older than 18 years) who had been on PD for ≥3 months and ≥3 months on APD were included. Patients on continuous ambulatory PD or those with peritonitis within 3 months of the consent date were excluded. Individual treatment data from seven consecutive APD treatment sessions with consistent dialysate composition for each cycler exchange were collected for each patient.

Results

Thirty-nine patients met the inclusion criteria and were enrolled. The probability of yielding a positive UF was 48.9% for cycle 1, rising to 90.5% by cycle 6. Adjusting for average dextrose concentration, dwell time, fill volume, solute transfer rate, and number of cycles, we observed that cycles 2–6 achieved progressively higher UF volumes than cycle 1 (P < 0.001). The first and last cycles demonstrated significantly different cycle UF volumes compared with a middle cycle (−230 and 277 ml, respectively, P < 0.001).

Conclusions

We observed a consistent increase in UF volumes achieved per cycle over the course of an APD treatment session with numerous clinical and physiologic implications. This provides the foundation for future studies investigating peritoneal intercycle variations and membrane physiology.
Productive and Consumptive Emission Characteristics of Energy-related Nitrogen Oxides in Eastern Chinese Cities
Authors: Han Shuangying , Huang Wei , Cui Shenghui , Gao Bing , Zhai Yuanxiao
Published: July 2024

Nitrogen oxides (NO
x
) have long been the focus of air pollution control. Examining the spatial and driving characteristics of NO
x
emissions at the urban scale and from the supply-chain perspective is critical. Using the inventory method and the environmentally extended input–output analysis, energy-related NO
x
emissions of 90 cities in eastern China were calculated, and the spatial patterns and driving sectors of urban emissions were analyzed from both production- and consumption-based perspectives. The results show that the production-based emissions of eastern Chinese cities are substantially affected by their industrial structure and are higher in the north and lower in the south. The cities with higher consumption-based emissions are mainly those with large populations and relatively developed economies. Production-based NO
x
emissions per unit gross domestic product (GDP) are higher in the north and lower in the south, and emissions per unit area are generally higher in coastal areas and lower in inland areas. The emission intensities of 5 selected major urban agglomerations differ, due to the influences of industrial structure and population density. The consumption-based NO
x
emissions per capita are mainly affected by urban affluence and consumption patterns. The sectors that contribute most to the production-based emissions per unit GDP are mainly “mining and processing”, “petroleum, chemical and non-metallic mineral products”, “metal products”, “production and supply of electricity, natural gas and water” and “transportation, storage, and postal services”, while the sector that contributes most to the consumption-based emissions per capita is the construction industry. Emission reduction strategies are proposed for both consumption-oriented and production-oriented cities.
Targeted Gene Therapy: Promises and Challenges in Disease Management
Authors: Vickram Agaram Sundaram , Manikandan Sivasubaramanian , Richard Titus , Lakshmi S. Vidhya , Chopra Hitesh
Published: July 2024

Targeted gene therapy may revolutionize disease treatment by precisely treating genetic defects. This method targets particular cells or tissues with therapeutic genes to treat a variety of genetic problems, including cancer, hereditary diseases, and viral infections. Viral, nonviral, and genome editing techniques such as CRISPR-Cas9 are used for targeted gene therapy to fix or modify disease-causing genes with minimal off-target effects. The issues of vector immunogenicity, off-target mutations, and gene delivery to target cells persist despite tremendous progress. The successful implementation of targeted gene therapy is further hindered by hereditary illness complexity and genetic background diversity. These difficulties require multidisciplinary cooperation, novel vector design, and thorough preclinical and clinical assessments. The long-term and unforeseen effects of gene editing must also be considered from an ethical viewpoint. Targeted gene therapy has considerable therapeutic promise, but more research and technological advances are needed to overcome limitations and develop safe and successful clinical treatments.
A Structural Mimic of Carbonic Anhydrase in Zeolitic Imidazolate Frameworks via Trans-functionalization for Enhancing Hydrolytic Activity
Authors: Meng Fanchen , Xu Cheng , Zhang Linghai , Huang Xiaohan , Zhang Xinglong , Zhang Wenlei , Luo Yongqi , Zhang Weina , Huang Wei , Huo Fengwei , Zhang Suoying
Published: July 2024

Metal-organic frameworks (MOFs) have been widely considered as ideal platforms for the preparation of biomimetic catalysts, but it remains challenging to fabricate MOF-based enzyme-like catalysts with optimal activity. Here, we leverage the inherent flexibility of MOFs and propose a novel trans-functionalization strategy to construct a carbonic anhydrase (CA) mimic by the structural transformation from ZIF-L to ZIF-8. Theoretical and experimental results reveal that during the structural transformation, the hydroxyl group will preferentially coordinate with the interlayer Zn clusters to form the CA-like active center Zn-N
3
-OH. Therefore, more accessible active centers are generated on the as-prepared ZIF-8-OH, resulting in substantially enhanced catalytic activity in the hydrolysis of
para
-nitrophenyl acetate.
Hepatic Surf4 Deficiency Impairs Serum Amyloid A1 Secretion and Attenuates Liver Fibrosis in Mice
Authors: Wang Bingxiang , Li Huili , Gill Govind , Zhang Xiangyan , Tao Geru , Liu Boyan , Zhai Lei , Chen Wei , Wang Hao , Gu Hong-mei , Qin Shucun , Zhang Da-wei
Published: July 2024

Liver fibrosis is a severe global health problem. However, no effective antifibrotic drugs have been approved. Surf4 is primarily located in the endoplasmic reticulum (ER) and mediates the transport of secreted proteins from the ER to the Golgi apparatus. Knockout of hepatic Surf4 (
Surf4
LKO
) in mice impairs very-low-density lipoprotein secretion without causing overt liver damage. Here, we found that collagen levels are significantly reduced in the liver of
Surf4
LKO
mice compared with control
Surf4
flox
mice, as demonstrated by proteomics, Western blot, and quantitative reverse transcription polymerase chain reaction. Therefore, this study aims to investigate whether and how hepatic Surf4 affects liver fibrosis. We observed that CCl
4
-induced liver fibrosis is significantly lower in
Surf4
LKO
mice than in
Surf4
flox
mice. Mechanistically, hepatic Surf4 deficiency reduces serum amyloid A1 (SAA1) secretion and hepatic stellate cell (HSC) activation. Surf4 coimmunoprecipitates and colocalizes with SAA1. Lack of hepatic Surf4 significantly reduces SAA1 secretion from hepatocytes, and SAA1 activates cultured human HSCs (LX-2 cells). Conditioned medium (CM) from Surf4-deficient primary hepatocytes activates LX-2 cells to a much lesser extent than CM from
Surf4
flox
primary hepatocytes, and this reduced effect is restored by the addition of recombinant SAA1 to CM from Surf4-deficient hepatocytes. Knockdown of SAA1 in primary hepatocytes or TLR2 in LX-2 cells significantly reduces LX-2 activation induced by CM from
Surf4
flox
hepatocytes but not from
Surf4
LKO
hepatocytes. Furthermore, knockdown of SAA1 significantly ameliorates liver fibrosis in
Surf4
flox
mice but does not further reduce liver fibrosis in
Surf4
LKO
mice. We also observe substantial expression of Surf4 and SAA1 in human fibrotic livers. Therefore, hepatic Surf4 facilitates SAA1 secretion, activates HSCs, and aggravates liver fibrosis, suggesting that hepatic Surf4 and SAA1 may serve as treatment targets for liver fibrosis.
Utjecaj različitih vrsta krojnih slika na iskoristivost tekstilnih materijala
Authors: Jordeva Sonja , Zhezhova Silvana , Golomeova Longurova Sashka , Risteski Sanja , Tudzarova Advokadov Daniela , Dimitrijeva-Kuzmanoska Vangja
Published: July 2024

The largest percentage of the costs of making clothes belongs to the textile material from which the clothes are made. The essential process in making clothes is the process of cutting the clothes. Before cutting, the cutting pieces and their positions are placed in the cutting marker closer to each other, which will achieve a minimum consumption of the fabric. This paper aims to show the effect of different types of cutting markers on the utilization of textile materials. Emphasis is made on fitting fewer and more sizes in one cutting marker, all in order to practically prove that the type of cutting marker significantly affects the consumption of the textile material from which the clothes are made. In the experimental part, two different orders are shown, with two different models of women’s trousers, but equal size representation and identical fabric. A comparative analysis was made between the efficiency of cut markers with fewer and more sizes contained in the cut marker. The obtained results give a direct conclusion that different types of cutting markers can significantly affect the consumption of textile material, that is, that, using cutting marker in which pieces of more sizes are integrated into one cut marker, the consumption of textile material is significantly reduced.
STRATEGIC MANAGEMENT OF SUSTAINABLE DEVELOPMENT OF THE LIVESTOCK INDUSTRY AT THE REGIONAL LEVEL
Authors: Nechaeva Marina , Antonova Dar'ya , Pavlov Aleksey
Published: July 2024

The livestock industry is a fundamental part of agriculture. The relevance of developing a sustainable livestock development system is due to a number of global and local factors that have a significant impact on modern agricultural systems. The article examines the current state of the livestock industry in the Russian Federation, as well as in the Nizhny Novgorod region. Ensuring the sustainable development of animal husbandry is an important aspect in the formation and assessment of the country's food security. Criteria for the sustainable development of the industry can serve not only economic indicators, including profitability, gross profit, etc., as well as indicators of social sustainability, which include the quality of life of the population, the development of human resources, etc., but also directly indicators characterizing the production of livestock products, the preservation of animal health, etc. In this regard, measures to ensure sustainable development are of particular relevance.
In order to determine the main directions of development, we have compiled a strategic map. The strategic map serves as a tool for visualizing, planning and implementing a development strategy, taking into account many factors and stakeholders. The development of a strategic map for the sustainable development of livestock is a key element for achieving a balance between economic efficiency, social justice and environmental sustainability. A methodological tool for drawing up a strategic map has been developed, providing a systematic approach to the issue under consideration with the allocation of the following "pools": human resources, innovation, financing, as well as active marketing.
COMPARATIVE ANALYSIS OF AUTHOR'S METHODOLOGIES OF SUSTAINABLE DEVELOPMENT ASSESSMENT AT THE REGIONAL LEVEL
Authors: Bal'cezhak Marina
Published: July 2024

Measurement of sustainable development is a separate area of research necessary for the formation and adoption of management decisions related to the development of the country's regions. The article presents a comparative analysis of various approaches and methodologies of domestic authors to assess sustainable development at the regional level. The study reveals the prevailing sources of information in the methodologies, the principles of selection of indicators and distribution by groups, methods and tools of assessment, interpretation of results, territorial coverage of approbation. Most authors adhere to the approach of deriving a consolidated aggregate index in combination with integral indicators for each component of sustainable development of the region, expanding the possibilities of interpreting the results. When forming the composition of indicators, choosing approaches and methods of measurement, researchers take into account the degree of severity of problems in achieving sustainable development goals in the region. At the same time, the principle of equal value of each component of sustainable development in accordance with the triune concept is not taken into account by all authors. In recent works, the wide inclusion of environmental indicators is recorded, which is due to the relevance of the implementation of the concepts of “low-carbon” and “green” economy. In general, the methodologies used to assess the sustainable development of regions have both advantages and disadvantages and are related to the objectives of researchers.
Polis Vazife ve Salahiyet Kanununa Göre Önleme Aramasında Yetki ve Yetki İle Alâkalı Ve Önemli Bazı Hususlar
Authors: Akkoyunlu Sencer Abdullah
Published: July 2024

Önleme araması, özel hayatın gizliliğine yönelik ileri düzeyde müdahale teşkil eden bir faaliyettir. Polis önleme araması yaparak suç işlenmesine neden olabilecek, tehlike doğurabilecek eşyaları araştırmakta ve bu türden eşyalara ulaşmaya çalışmaktadır. Arama kararı alma yetkisi Anayasanın 20’nci maddesiyle hakime, gecikmesinde sakınca bulunan hallerde ise kanunla yetkilendirilmiş merciye verilmiştir. Polis Vazife ve Salahiyet Kanuna göre önleme araması kararı almaya yetkili hakim sulh ceza hakimidir; aynı Kanununa göre arama kararı vermeye yetkili merci ise vali ve kaymakamdır (mülki amirdir). Bununla birlikte Polis Vazife ve Salahiyet Kanununu göre kolluk amiri de bazı hallerde önleme araması kararı alabilmekte ve hatta Anayasaya aykırı olmakla beraber polis herhangi bir arama kararı gerekmeksizin önleme araması yapabilmektedir. Önleme araması kararının alınması ile ilgili olarak yargı yeri (sulh ceza hakimi) ile idare (vali ve kaymakam, polis bazen kolluk amiri) yakın ilişki içerisinde olup, aramanın yapılmasında her ikisinin de rolü bulunmaktadır. Bu yakın ilişkinin ve rolün sonucu olarak önleme araması kararı alma yetkisinin detaylı olarak incelenmesi gerekmektedir. Makalemizde önleme araması kararı alma yetkisini, yetki ile alâkalı, önemli gördüğümüz hususları, doktrinde yer alan düşünceleri de göz önünde bulundurmak suretiyle ele almakta, konuyla ilgili düşünce ve önerilerimizi dile getirmekteyiz.
A Study on the Change and Structure of Mahan interaction Network in Northern Kyush: Focusing on the Mahan pottery From the late Yayoi period to the early Kofun period
Authors: Jung Jaehyun , Jang Seulji ,   The hoseo Archaeological Society
Published: July 2024

Records implying the interaction between the Korean Peninsula and the Japanese archipelago are found in works such as the 『漢書地理志』 and the 『魏志倭人伝』. In addition, considering that the Nakrang (樂浪)·Daebang (帶方) route was inevitably through the Mahan region, it can be seen that Mahan was also located within the Korea-Japan interaction network. This is evidenced by the large number of Mahan pottery found in northern Kyushu, where various Korean Peninsula-type pottery are concentrated. This article attempts to estimate the location and operational strategy of the Mahan interaction network from a comparative perspective, paying attention to the specificity of the logistics environment in northern Kyushu.
The temporal and spatial aspects of Mahan type pottery excavated from northern Kyushu are re-examined and compared with those of the Nakrang and Byeon·jinhan(弁·辰韓) type pottery that were introduced at the same time. Through this, it can be admitted that the Mahan interaction network has been organized since the second half of the late Yayoi period, but it is judged that they have taken advantage of and participated in the network established around Nakrang in the past. Mahan's new initiative is recognized in the process of dismantling and reorganizing existing networks from the beginning to the first half of the Early Kofun Period. Furthermore, by looking at the background of the establishment and dismantling of the Nishijinmachi[西新町] ruins, which are the inflection points, from a relative perspective and operational strategy, the possibility that they had a trade structure vulnerable to risk management was pointed out.
Through the above results, it was possible to estimate the specific status and role of the Mahan interaction network identified in northern Kyushu. It was possible to evaluate Mahan's external capabilities in a new position during the Proto-Three Kingdom Period, which had previously received relatively little attention as part of the Samhan or as part of the Baekje. Through this, it is expected to be a study that can contribute to the reconstruction of the multifaceted and comprehensive aspects of external relations formed by Mahan while evoking research on Korea-Japan interactions during the Proto-Three Kingdom Period.
Türkiye Denizlerinde Dağılım Gösteren Vantuz Balıkları (Echeneidae)
Authors: Irmak Erhan
Published: July 2024

Bu çalışma Türkçe’de vantuz balıkları olarak bilinen genellikle köpekbalıkları, vatozlar, deniz kaplumbağaları, deniz memelileri veya büyük kemikli balıklara tutunarak yaşamını sürdüren Echeneidae familyasının Türkiye sularında ki türlerine yönelik incelemeleri kapsamaktadır. Echeneidae familyasının en nadir türü olan Remora australis’in fiziksel kanıtı niteliğinde ki bir birey bu çalışmada rapor edilmektedir. Ayrıca diğer familya üyelerinden Remora osteochir ve Echeneis naucrates’in de Türkiye denizlerindeki dağılımları ve konaklarıyla olan ekolojik ilişkileri saha gözlemlerine dayalı olarak ortaya konulmaktadır. Sonuç olarak bu çalışma ile Türkiye ihtiyofaunasında dört tür ile temsil edilen Echeneidae familyasının mevcut statüsü ve ekolojik ilişkileri incelenmekte ve elde edilen türlere ait yeni kayıtlar sunulmaktadır.
Length-Weight Relationship of Diamondback puffer Lagocephalus guentheri from the northeastern Mediterranean Sea
Authors: Doğdu Servet Ahmet , Turan Cemal
Published: July 2024

The length-weight relationship data is important basic information that helps to compare species between populations and habitats. In this study, we provide detailed information on the length-weight relationships and condition factors of Lagocephalus guentheri from the Iskenderun Bay, northeastern Mediterranean Sea. A total of 408 (262 Female, 146 Male) specimens were collected on commercial trawlers by local fishermen caught between December 2022 to December 2023 from Iskenderun Bay. The total length range was 11.0-36.9 cm and 11.2-36.7 cm for females and males, respectively. The total weight values of females and males ranged from 20.30-1080.50 g and 20.50-1012.36 g, respectively. The length-weight relationship of L. guentheri was calculated as W = 0.0098 × L3.2145 (R2 = 0.9960) for females, W = 0.009 × L3.2399 (R2 = 0.9963) for males, and W = 0.0095 × L3.2243 (R2 = 0.9962) both sexes. The Fulton’s condition factor was observed as 1.2384 for females, 1.2504 for males, and 1.2335 for both sexes. This study is the most recent reference on length-weight relationships and condition factors for L. guentheri after correction of species identification. It is very important to determine the population parameters of pufferfish species to shed light on the studies to be carried out to restore the ecological balance in the Mediterranean ecosystem. This study will provide basic information that will be useful for fisheries scientists and managers in the Mediterranean Sea.
Condition factor and meat yield of invasive zebra mussels (Dreissena polymorpha) in Lake Çıldır, Karakaya, and Keban Reservoirs in Turkey
Authors: Atasaral Şebnem , Çiloğlu Erhan
Published: July 2024

This study presents a comprehensive view of the body condition and meat yield of Dreissena polymorpha in Çıldır Lake, Keban, and Karakaya reservoirs. A diverse sample of 472 D. polymorpha (154 from Çıldır Lake, 169 from Karakaya Reservoir, and 149 from Keban Reservoir) was collected. The condition index of zebra mussels in the Keban reservoir was the highest, with an average of 46,88, followed by zebra mussels in the Karakaya reservoir with 46,33. The zebra mussel in Çıldır Lake showed the lowest value, averaging 20,77. The fresh meat yield of zebra mussels in Çıldır Lake was lower than the fresh meat yields of zebra mussels in the Keban and Karakaya reservoirs. However, dry meat yield was higher. The dry meat yields of zebra mussels in all three reservoirs were found to vary significantly (P<0.05).
The influence of job embeddedness and organizational commitment on organizational citizenship behavior in BULOG
Authors: Haryati Endri , Widodo Agus Purbo , Widodo Teguh Setiawan
Published: July 2024

Job embeddedness means employee engagement in an organization through social networks, namely trust and cohesion. Embeddedness are all factors that involve employees in their work, this can happen if there is a match between work values and individual values and community values with individual values. Organizational commitment is an individual's loyalty to the organization. Those who have high commitment tend to persist more and have lower absenteeism than those who have low commitment. Organizational Citizenship Behavior (OCB) is part of the science of organizational behavior, OCB is a form of work behavior that is usually not visible or taken into account. BULO G is a state-owned public company engaged in food logistics. The company's business scope includes logistics/warehousing business, surveying and eradicating pests, providing plastic sacks, transportation business, food commodity trading and retail business. Based on the results of the analysis and discussion, this research uses Path Diagrams and Hypothesis Testing with the Partial Least Squares (PLS) method using the SmartPLS 3.0 program. Based on this conclusion, Based on these results, it can be said that job embeddedness and organizational commitment have a significant effect on organizational citizenship behavior in BULOG employees.
Analysis of the implementation of the exclusive breastfeeding policy in the working area of Panombean Panei Health Center
Authors: Rika Maya Sari Saragih  , Sitorus Rotua Sumihar , Ginting Desideria Yosepha
Published: July 2024

Abstract
According to Government Regulation No. 33 of 2012 it is stated that Exclusive Breast Milk, hereinafter referred to as Exclusive Breast Milk, is breast milk given to babies from birth for 6 (six) months, without adding and/or replacing it with other food or drinks. . The impact if the mother does not give exclusive breastfeeding, the baby will be at risk of experiencing health problems and being susceptible to infection. This research is a descriptive qualitative research. The research was conducted at the Panombean Panei Health Center. The research informants were 7 people, the samples were taken by snowballing. Data were analyzed in depth in narrative form by means of data reduction, data presentation, drawing conclusions/verification.The results of the study show that the implementation of the exclusive breastfeeding program at the Panombean Panei Health Center has not been maximized, for the last 4 years the average <40% is still far from the national target of 85%. Bureaucratically, the parties responsible for and involved in the exclusive breastfeeding program are the head of the Puskesmas, the MCH program holder, the nutrition program holder, and the village midwife. Recording and reporting is carried out by the village midwife every month and the health center reports to the Simalungun District Office at the beginning of the month. The resources of health personnel in promoting the exclusive breastfeeding program are sufficient. ASI corner is available but not utilized. Facilities and infrastructure for counseling are still lacking such as leaflets and booklets. The source of funds comes from Health Operational Assistance (BOK) combined with other MCH programs. There is no charge for the implementation of the exclusive breastfeeding program. The disposition or attitude of health workers is good and friendly in providing counseling about exclusive breastfeeding, providing information that is easily understood by mothers. Not all mothers can attend posyandu because of work. Supervision is not carried out specifically and the sanctions are only in the form of a warning. Communication in the implementation of the exclusive breastfeeding program was carried out by health workers by going into the field providing counseling or education by cooperating with the village midwife by forming a class for pregnant women and a class for babies. The frequency of counseling is not routine because the area of the Panombean Panei Health Center is wide.
Keywords: Application of Policy, Exclusive Breastfeeding Program, Health Center
Lower Back Pain Prevention Education In The Community In Sidodadi Village, Beringin District
Authors: Bintang Siti Sarah Bintang Sarah , Berampu Sabirin , Handayani Dwi , Jannah Miftahul
Published: July 2024

Low back pain (LBP) is characterized by pain, muscle tension, or stiffness localized below the ribs and above the crease of the buttocks, with or without leg pain. It can be categorized as non-specific LBP, a serious condition, or a radicular syndrome. Classifying LBP as acute (lasting less than 6 weeks), sub-acute (6 to 12 weeks), or chronic (more than 12 weeks) can aid in prognosis and guide management. Predictors of persistent disability from LBP include genetics, symptoms, lifestyle, social and psychological factors, and comorbidities. 7 However, no single risk factor is strongly predictive. The mechanisms of action of these risk factors are still unknown, but sleep disturbances and severe stress, for example, may lead to excessive activation of glial cells and thus to low-grade inflammation, leading to central sensitization, i.e. widespread pain. The implementation of community service activities was carried out through notification via the information platform at the village office with a sample of 15 residents in Sidodi Village, Beringin District. It is recommended that residents maintain their health, especially physically, so that, in addition, it is also recommended to continue to pay attention to or apply a healthy daily lifestyle and maintain their physical condition so that they remain healthy.
Estado nutricional de pacientes en una sala de rehabilitación posterapia intensiva por COVID-19
Authors: Adaglio Julieta , Del Rio Luisina , Antonini Mirta , Sayar Romina
Published: July 2024

Introducción: la estancia prolongada en la unidad de terapia intensiva (UTI) es un factor de riesgo de desnutrición. Una intervención nutricional temprana con rehabilitación hospitalaria intensiva permite recuperar la fuerza muscular y el estado nutricional.
Objetivo: determinar la evolución del estado nutricional de pacientes post-UTI por COVID-19 en una sala de rehabilita- ción (SaRIP).
Métodos: estudio descriptivo, prospec- tivo en pacientes internados en la SaRIP luego de estancia prolongada en la UTI por COVID-19. Se evaluó peso e índice de masa corporal (IMC) en tres momentos, estado nutricional según la valoración glo- bal subjetiva (VGS) y fuerza muscular con dinamometría manual en dos momentos. Se calculó la media y la desviación están- dar (DE), y se evaluó la asociación entre variables con la prueba chi-cuadrado o la de Fisher y Wilcoxon, considerándose un nivel de significancia de p <0,05.
Resultados: se incluyeron 42 pacientes, 69,00 % hombres, con una edad media de 57,2 ± 13 años. La media de IMC al ingreso a la SaRIP fue de 26,82 ± 5,32 kg/m2 y en el alta de 26,99 ± 5,15 kg/m2 (p = 0,736). Según la VGS, un 88,10 % presentó desnu- trición al ingreso y 42,86 % al egreso (p = 0,002). El 50,00 % presentó incremento de peso con una media de 2,73 ± 2,07 kg y el 100 % incremento de fuerza de agarre con una media de 3,97 ± 3,64 kg.

Conclusiones: la mayoría de los pacien- tes ingresó a la SaRIP con desnutrición y en el alta se observó mejoría del estado nu- tricional, aunque gran parte continuó con alguna alteración y necesidad de suple- mentación oral y seguimiento nutricional.
Memorias de la mapu: boleando firuletes en la máquina del olvido
Authors:   , Cercato Gabriel Francisco
Published: July 2024

Analiza el discurso existente en la ciudad de La Plata desde el trasado urbano y como ciudad-monumento, constituida en símbolo del proyecto de país que tenía la Generación del Ochenta. Se presenta, a su vez, un antidiscurso de la misma, a partir de las esculturas neo-neogóticas contemporáneas del completamiento de la Catedral de La Plata que desocultan la máquina del olvido en que se convirtió la ciudad. Como conclusión propone una refundación simbólica de la ciudad a partir de las memorias americanas olvidadas.
THE IMPACT OF DIET COMPONENTS ON THE OCCURRENCE OF GASTROINTESTINAL CANCERS IN POLAND
Authors: Zatyka Piotr , Słomczyński Adam , Wolak Jerzy , Pawłowska Agata , Rabenda Michal , Janik Piotr , Ochotnicka Aleksandra , Marcinkiewicz Anita , Galińska-Zatyka Eliza
Published: July 2024

The subject of our considerations was the impact of individual dietary components on the occurrence of gastrointestinal cancers. These cancers are relatively common in our population, which is why we focused on analyzing the influence of diet, a modifiable factor that is the subject of intense research. We particularly emphasized the vegetarian diet, which reduces the incidence of these diseases. We thoroughly analyzed specific dietary components and their potential impact on the occurrence of these cancers. The aim of this study was to increase public awareness of how diet significantly influences our health. Additionally, we hope that it will motivate readers to change their dietary habits and eliminate harmful components. Methods: We analyzed specialized literature and scientific articles on PubMed to demonstrate the relationship between specific dietary components and the occurrence of gastrointestinal cancers. Conclusion: In our study, we demonstrated the correlation between individual dietary components and the occurrence of gastrointestinal cancers. Additionally, we highlighted the positive impact of a vegetarian diet compared to a meat-based diet in the pathogenesis and susceptibility to these diseases.
İç Göçlerin Kentlerin Siyasal Eğilimlerinin Değişimine Etkileri: Bursa Örneği
Authors: Bahçalı Selin , Özözen Kahraman Selver
Published: July 2024

Kentsel mekânlar üzerinde çeşitli etkilere sahip olan iç göçler, siyasal davranış kalıplarını da etkilemektedir. Hedef mekândaki göçün hacmi, yeni kentlilerin sosyo-ekonomik yapı ve kimliklere göre kümelenmeleri kentlerin geleneksel seçmen davranışlarını değiştirebilmektedir. Bu da mekânın kentsel alanlarda siyasal kutuplaşmalarını arttırır. Yoğun göç alan kentlerde bu durumun etkisi daha yüksektir. Nüfusunun yarısına yakınını diğer illerden gelen göçmenlerin oluşturduğu Bursa kenti, iç göç ve seçim ilişkiselliğini en iyi yansıtabilecek mekânlardan birisidir. Bu makalede Bursa’nın aldığı iç göçlerin genel seçimler üzerindeki etkisine odaklanılmıştır. Yüksek Seçim Kurulu’nun 2002-2015 Kasım arasındaki beş genel seçim sonucu kullanılarak, Bursa metropoliten alanı içerisinde yoğun göç almış 33 mahallenin siyasal deseni ortaya konulmuş ve köken bölgeyle seçmen davranışı arasındaki ilişkisellik Çok Boyutlu Ölçekleme (MDS) analiziyle incelenmiştir. Bulgulara göre, Bursa’da köken bölgeyle birleşmiş etnik ve inanç kimliklerine göre kümelenmenin daha yüksek olduğu mahallelerde hemşehri kümelerinin siyasi paterni önemli düzeyde etkilediği belirlenmiştir. Kaynak bölgenin hâkim seçmen davranışı hedef bölgede güçlü kümeleme gösteren mahallelerde devam ettirildiği gözlenmiştir. Bu bağlamda incelenen mahallelerdeki göçmenlerin önemli bir kısmının oy verme davranışının sosyo-psikolojik temelli olduğu söylenebilir.
Kent Nüfusu Tespitinde Belediye Kanunu Sorunu: Kastamonu İli Örneği
Authors: Türkan Okan , Tepealtı Fahrettin
Published: July 2024

Türkiye’de akademik alan başta olmak üzere çeşitli platformlarda kent ve kır nüfusuyla ilgili ihtiyaca binaen kullanılan verilerin elde edilmesinde bazı sorunlar olduğu görülmektedir. Söz konusu platformların ihtiyaç duyduğu verilerin temininde Türkiye İstatistik Kurumu’nun (TÜİK) yayınlamış olduğu veriler kullanılmaktadır. TÜİK tarafından yayınlanan veriler yürürlükte olan 6360, 5393 ve 5216 sayılı yasalardan kaynaklı hatalar içermektedir. İlgili yasalardan dolayı Türkiye’deki il düzeyinde yayınlanan kent nüfus değerleri sadece büyükşehir belediyeli illerde değil aynı zamanda büyükşehir belediye örgütü bulunmayan 51 ilde de doğruyu yansıtmamaktadır. Büyükşehir belediye örgütü bulunan 30 ilde 6360 sayılı yasa gereği köy tüzel kişilikleri kaldırılmış olup bu yerleşmeler mahalle olarak kabul edilmektedir. Bu çerçevede 30 ilde kırsal nüfus gözükmemektedir. Diğer 51 ilde ise TÜİK, köy ve belediye nüfuslarını yayınlamakta olup kurum tarafından belediye nüfusları kent nüfusu olarak kullanılmaktadır. Büyükşehir belediye örgütü bulunmayan 51 ille ilgili kullanılan kent nüfusunun geçmiş ve aktüel çalışmaların neredeyse tamamında TÜİK’in verilerinin doğru kabul edilerek doğrudan kullanıldığı görülmektedir. Bu bağlamda kent ve kır nüfus tespitiyle ilgili sadece büyükşehir belediyeli illerde yasadan dolayı sorun olduğu, diğer illerde ise sorun olmadığı düşünülmektedir. Ancak 51 il ile ilgili 5393 sayılı yasanın hükümleri ve bu hükümlere dayanılarak yapılan düzenlemeler TÜİK tarafından bu illerin kent nüfuslarıyla ilgili verilerinin de hatalı olmasına neden olmaktadır. 5393 sayılı yasanın birleşme ve katılmayı düzenleyen 8. Maddesi bazı köylerin belediye sınırlarına dahil edilmesine olanak tanımaktadır. TÜİK ise belediye nüfuslarını kent nüfusu olarak kullandığı için büyükşehir belediye örgütü bulunmayan 51 ilin kent nüfusu verilerinde hatalar yer almaktadır. Bu durum çalışmanın konusunu teşkil eden Kastamonu ili için de geçerlidir.
Çalışmanın merkezini oluşturan Kastamonu ilinde olduğu gibi büyükşehir belediye örgütü bulunmayan 51 ilin kent nüfusu tespiti sorunu belediye sınırları içerisinde kalan mahallelerin kentsel doku içinde olup olmadıklarının belirlenmesiyle mümkündür. Bu sorun saha çalışmaları, istihdam verileri ve uydu görüntüleri yardımıyla çözülebilmektedir. Çalışma sonucunda Kastamonu iline yönelik TÜİK tarafından üretilen kent ve kır nüfusu değerlerinin gerçeği yansıtmadığı görülmüştür.
janela e a grade na pintura de Luiz Zerbini e Ana Calzavara
Authors: Lima Wagner Jonasson da Costa
Published: July 2024

O artigo aborda a pintura dos brasileiros Luiz Zerbini e Ana Calzavara, sobretudo trabalhos que exibem o motivo da “vista através de uma janela aberta”, com o intuito de discutir o efeito peculiar de ambiguidade espacial – a alternância entre espaço profundo, raso e decorativo – visível nessa produção. Sugere, tendo em vista o pluralismo estilístico da arte contemporânea, que os artistas alcançaram tal efeito ao considerar a vista através de uma janela aberta como motivo que favorece a reunião de diferentes protótipos pictóricos, o da janela albertiana e o da grade modernista. Como via de investigação da questão levantada, o texto adota a análise da “poiética/poética” de Zerbini e Calzavara.
Revitalization or Alienation: Reflections on Continuation of Traditional Culture
Authors: Wang Jing , He Ming-Ming , Tsai Shu-Chen
Published: July 2024

With urbanization and industrialization, the future of traditional villages and their culture has been discussed extensively. Tourism is an important way to promote economic growth and cultural dissemination as it brings hope to revive traditional villages and local cultures. We explored the role of cultural heritage tourism in the process of cultural dissemination that affects cultural kernel. We conducted a case study of Xunpu Village and obtained textual data through field study and interviews. The results showed that in the process of developing cultural heritage tourism, the traditional culture transmitted outward from Xunpu Village has experienced alienation and absence. The importance of cultural heritage tourism is based on cultural authenticity, but the loss of cultural authenticity in the development of Xunpu Village is not conducive to the development of sustainable tourism and the long-term well-being of the residents.
Frequency of Hypocalcemic Seizures in Children with Afebrile Seizure: From 2 months - 2 years in a Tertiary Care Hospital
Authors: Sultana Shafaq , Waheed Isma , Ahmad Sadia mahmood , Qureshi Muhammad Nadeem , Siddique Tahir Saeed
Published: July 2024

Objective: To determine the frequency of hypocalcemic seizures in children with afebrile seizure from age 2 months - 2 years.                                                                                                                                                                                                         
Methodology: This Descriptive Cross-Sectional study was conducted in Pediatric Department of Ayub Teaching Hospital Abbottabad for a period of six months (15th April, 2017 to 15th October, 2017). Total 130 cases fulfilling the inclusion criteria were enrolled in the study after approval from ethical committee of hospital and informed consent from the parents of children. A detailed history and examination were done and blood samples for serum calcium level were sent to the hospital laboratory along with other routine investigation to rule out the cause. All data was analyzed using SPSS version 21.
Results: Out of 130 cases 48(36.9%) children had hypocalcemia while 82(63.1%) were normocalcemic. 79 (60.8%) were males and 51 (39.2%) were females. The mean age of children was 13.03 ± 6.81 months. The average calcium level was 8.23±1.51mg/dl.
Conclusion: It has been concluded that afebrile seizures occur frequently in children with hypocalcemia. Thus, we got the local evidence regarding this association and recommend to screen all new afebrile seizure cases for hypocalcemia.
Key words: Hypocalcemic fits, children, afebrile seizures, hypocalcemia
ПОНЯТТЯ СТАЛОГО РОЗВИТКУ АГРАРНОГО СЕКТОРА ТА ЙОГО ВПЛИВ НА ПРОДОВОЛЬЧУ БЕЗПЕКУ УКРАЇНИ
Authors: Сідляр Микола , Хащевой Євген
Published: July 2024

У роботі досліджується вплив сталого розвитку аграрного сектора на продовольчу безпеку України в умовах сучасних викликів. Проаналізовано структурні та організаційні проблеми та фактори аграрного сектора, що призводять до зниження продовольчої безпеки. Сталий розвиток аграрного сектора розглядається як баланс між економічними, соціальними та екологічними складовими. Запропоновано заходи для покращення стану аграрного сектора, що сприятиме зміцненню продовольчої безпеки країни.
КІБЕРБЕЗПЕКА ЯК ДЕТЕРМІНАНТА ОБАЧЛИВОЇ ФІНАНСОВОЇ ПОВЕДІНКИ ДОМОГОСПОДАРСТВ
Authors: Вовченко Оксана
Published: July 2024

В роботі автором запропоновано підхід до дослідження кібербезпеки як інструменту вдосконалення особистої фінансової поведінки домогосподарств. Охарактеризовано спектр кіберзагроз, типи загроз фінансовій безпеці домогосподарств в онлайн-середовищі та обґрунтовано важливість протидії фінансовим втратам від них в умовах цифровізації. Запропоновано напрями підвищення рівня кібербезпеки та окреслено особливості формування обачливої фінансової поведінки домогосподарств з урахуванням сучасних тенденцій.
ПОКАЗНИКИ ОЦІНЮВАННЯ ЕМОЦІЙНОЇ КОМПЕТЕНТНОСТІ УПРАВЛІНСЬКИХ ПРАЦІВНИКІВ
Authors: Дарміць Ростислав , Фесенко Діана
Published: July 2024

Охарактеризовано у хронологічному порядку моделі та методики вибраних науковців для вимірювання емоційного інтелекту. Розроблено та структуровано локальні показники для оцінювання складових емоційної компетентності. З урахуванням умов провадження поточної діяльності управлінця доповнено і розвинуто матрицю Ейзенхауера на засадах виокремлення найбільш доцільних характеристик емоційної компетентності (стресостійкість, самоконтроль, комунікабельність, конформність, неконфліктність, адекватність).
СОЦІАЛЬНА СКЛАДОВА КОНФЛІКТУ У ТРУДОВОМУ КОЛЕКТИВІ
Authors: Кравець Ірина , Доброжинський Андрій
Published: July 2024

У статті розглядається проблема соціальної складової конфліктів у трудових колективах. Висвітлюються причини виникнення трудових конфліктів на мікрорівні та їх негативний вплив на соціально-психологічний клімат, мотивацію працівників і продуктивність праці. Наголошується на важливості діагностики й аналізу конфліктних ситуацій, а також формування ефективної системи їх запобігання та врегулювання. Пропонуються заходи щодо профілактики конфліктів, серед яких: розвиток організаційної культури, оптимізація системи мотивації персоналу, налагодження комунікацій, навчання керівників методам конфліктного менеджменту, створення примирних органів, належне правове регулювання трудових відносин. Акцентується увага на необхідності комплексного підходу до успішної профілактики та врегулювання конфліктів у трудових колективах.
FORMATION OF MECHANISM FOR ENSURING THE COMPETITIVENESS OF LARGE BREAD FACTORY (IN THE EXAMPLE OF “KHLIB-TRADE” LLC)
Authors: Kulinich Tetiana , Tymchyna Yurii , Yi Wang
Published: July 2024

The article considers the possibilities of creating a mechanism for ensuring competitiveness for a large bread factory with increased attention to its personnel, property (resource), production and sales, and organizational subsystems. The principle of building a scheme for a comprehensive assessment and ensuring the competitiveness of a bread factory with basic parameters and indicators is shown in the example of "Khlib-Trade" LLC. The main parameters and indicators of such an assessment are named. A step-by-step scheme for the development and implementation of an innovative competitive strategy for this enterprise based on the developed matrix of its SWOT analysis is presented.
TOWARDS ETHICAL AND SUSTAINABLE DEVELOPMENT IN BUSINESS MANAGEMENT WITH AI
Authors: Ivchyk V.
Published: July 2024

This article considers into the ethical considerations surrounding the integration of artificial intelligence (AI) in business management. As AI becomes more prevalent in decision-making and operations, businesses encounter numerous ethical challenges. These include concerns about algorithmic bias, transparency, workforce implications, and data privacy. The ethical implications of AI in business are complex and far-reaching. This thorough analysis examines real-world examples, ethical frameworks, and best practices to help businesses responsibly navigate these challenges. By proactively addressing these ethical dilemmas, businesses can harness the advantages of AI while maintaining ethical standards and societal values.
ТЕОРЕТИЧНІ ЗАСАДИ ФОРМУВАННЯ ТА ОЦІНЮВАННЯ ІНФОРМАЦІЙНОГО ЗАБЕЗПЕЧЕННЯ УПРАВЛІННЯ ЕНЕРГОЗБЕРІГАЮЧИМИ ПРОЄКТАМИ ПІДПРИЄМСТВ
Authors: Ємельянов Олександр , Дмитро Гаврась
Published: July 2024

Визначено структуру масиву інформації, необхідної для управління енергозберігаючими проєктами на підприємствах. Показано, що ця структура має ієрархічний характер і повинна містити чотири основні блоки інформації. Запропоновано послідовність кількісного оцінювання інформаційного забезпечення управління енергозберігаючими проєктами на підприємствах. Побудовано показник, за допомогою якого можливо здійснити таке оцінювання. Використання цього показника у практиці діяльності підприємств надасть можливість виявити резерви покращення інформаційного забезпечення управління їх енергозберігаючими проєктами.
BUSINESS DEVELOPMENT IN UKRAINE IN THE CONTEXT OF DIGITAL ECONOMICS
Authors: Denchyk Iryna
Published: July 2024

This article explores the trajectory of business development in Ukraine under the influence of digital economics. By examining key sectors, government initiatives, and the challenges and opportunities presented by digital transformation, we aim to provide a comprehensive overview of how Ukraine is adapting to the digital age and positioning itself in the global market. The study highlights the rapid growth of the IT sector, the significant strides in e-commerce, FinTech, and agriculture, and the critical role of government policies in fostering digital innovation. It also addresses the pressing challenges such as cybersecurity risks, digital skills gaps, and regulatory needs, offering policy recommendations to ensure sustainable growth. This multifaceted analysis underscores the transformative impact of digital economics on Ukraine’s business landscape, offering insights into its future trajectory in the global digital economy.
АНАЛІЗ ТА АНАЛІТИКА ВЕЛИКИХ ДАНИХ В МАРКЕТИНГУ ТА ТОРГІВЛІ КОНКУРЕНТНОГО ПІДПРИЄМСТВА
Authors: Науменко Максим
Published: July 2024

Технології великих даних — комплекс методів, алгоритмів і інструментів для обробки, аналізу та аналітики (в розподіленому масштабі) даних величезних обсягів і значної різноманітності в умовах постійного зростання, розподілу інформації по численних вузлах комп’ютерної мережі. Великі дані охоплюють будь-яку структуровану та неструктуровану інформацію, зібрану, збережену, пов’язану та проаналізовану як онлайн, так і офлайн.Ефективне управління великими даними корпорацій і компаній (і використання нових  знань, закономірностей та insights, отриманими з них), потенціал інтелектуального аналізу та аналітики великих даних – важливі інструменти для компаній у напрямку досягнення їх системного сталого розвитку. Розуміння того, як великі дані збільшують конкурентну перевагу компанії та трансформують її бізнес-моделі, є незамінним у контексті кризових явищ на ринках, що розвиваються.У статті розглядаються концептуальні особливості вирішення актуальної проблеми ефективного використання аналізу та аналітики Big Data в маркетингу та роздрібній торгівлі з метою підвищення ефективності та конкурентноздатності компаній та підприємств в умовах кризових явищ.Запропоновані науково-практичні результати рекомендовані до впровадження на підприємствах та компаніях не тільки в умовах України [1, 2], але для інших країн в умовах локальних та глобальних кризових явищ [3].
ФІНАНСОВА ІНКЛЮЗІЯ В УКРАЇНІ: СУЧАСНИЙ СТАН ТА ПЕРСПЕКТИВИ РОЗВИТКУ
Authors: Євтушенко Наталія , Стеценко Дмитро
Published: July 2024

Стаття присвячена аналізу стану фінансової інклюзії в Україні та визначенню основних напрямків її розвитку. У роботі розглядаються ключові показники фінансової інклюзії, такі як доступ населення до банківських послуг, використання електронних платіжних систем та рівень фінансової грамотності. Окрему увагу приділено проблемам та бар'єрам, що стримують розвиток фінансової інклюзії в країні, а також аналізу перспектив та можливостей їх подолання. Автори пропонують низку заходів для підвищення рівня фінансової інклюзії, серед яких удосконалення законодавчої бази, розвиток фінансових технологій та підвищення рівня фінансової освіти населення. Стаття є корисною для науковців, практиків та політиків, що цікавляться питаннями фінансової інклюзії та її роллю у соціально-економічному розвитку України.