bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Miracle Mouthwash plus Hydrocortisone Versus Prednisolone Mouth Rinses as Prophylaxis for Everolimus-Associated Stomatitis: A Randomized Phase II Study
Authors: Jones Vicky E. , McIntyre Kristi J. , Paul Devchand , Wilks Sharon T. , Ondreyco Sharon M. , Sedlacek Scot , Melnyk Anton , Oommen Sanjay P. , Wang Yunfei , Peck Susan R. , O'Shaughnessy Joyce A.
Published: March 2019

Background

Mammalian target of rapamycin (mTOR) inhibitor-associated stomatitis (mIAS) is a frequent adverse event (AE) associated with mTOR inhibitor therapy and can impact treatment adherence. The objectives are to evaluate two steroid-based mouthrinses for preventing/ameliorating mIAS in patients with metastatic breast cancer (MBC) treated with everolimus.

Materials and Methods

This prospective, randomized phase II study enrolled 100 postmenopausal patients with hormone receptor-positive MBC within the US Oncology Network who were initiating therapy with an aromatase inhibitor + everolimus (AIE; 10 mg/day). Patients were randomized to prophylactic therapy with one of two oral rinses (Arm 1: Miracle Mouthwash [MMW] 480 mL recipe: 320 mL oral Benadryl [diphenhydramine; Johnson & Johnson, New Brunswick, NJ, USA], 2 g tetracycline, 80 mg hydrocortisone, 40 mL nystatin suspension, water; or Arm 2: prednisolone [P] 15 mg/5 mL oral solution, 1.8% alcohol). Patients were instructed to swish/expectorate 10 mL of the assigned rinse for 1–2 minutes four times daily starting with day 1 of AIE treatment, for the first 12 weeks.

Results

A total of 100 patients received treatment (49 MMW; 51 P). The incidence of stomatitis/oral AEs during the first 12 weeks was 35% (n = 17/49) and 37% (19/51) in the MMW and P arms, respectively. The incidence of grade 2 oral AEs was 14% (7/49) and 12% (6/51) with MMW or P, respectively. There were two grade 3 oral AEs (MMW arm) and no grade 4 events. There was one everolimus dose reduction (MMW) and six dose delays (four MMW, two P) and one dose reduction + delay (MMW) during the first 12 weeks of treatment. No patients stopped steroid mouthwash therapy because of rinse-related toxicity.

Conclusion

Prophylactic use of steroid-containing oral rinses can prevent/ameliorate mIAS in patients with MBC treated with AIE. MMW + hydrocortisone is an affordable option, as is dexamethasone oral rinse.

Implications for Practice

This prospective phase-II study showed that two steroid-containing mouthrinses substantially reduced incidences of all-grade and grade ≥2 stomatitis and related oral adverse events (AEs), and the number of everolimus dose-delays and/or dose-reduction in metastatic breast cancer (MBC) patients receiving everolimus treatment plus an aromatase inhibitor. Both oral rinses were well tolerated and demonstrated similar efficacy. Prophylactic use of steroid mouth rinse provides a cost-effective option that substantially decreases the incidence and severity of mammalian target of rapamycin (mTOR) inhibitor-associated stomatitis and related oral AEs as well as the need for dose modification in MBC patients undergoing treatment with an mTOR inhibitor.
Novel evaluation of bender element transmitter response in transparent soil
Authors: Irfan Muhammad , Cascante Giovanni , Basu Dipanjan , Khan Zahid
Published: March 2019

Bender elements (BEs) are commonly used by geotechnical laboratories worldwide to measure the shear-wave velocity of soils. However, the actual behaviour of BEs inside the soil specimen has never been directly measured. There is experimental, numerical and analytical evidence that the shape and frequency content of the actual transmitter movement are different from the shape and frequency content of the input voltage signal, although this disparity has never been validated for BEs placed inside a soil specimen. In order to systematically investigate the disparity between the input signal and the actual transmitter response and to advance the understanding of the frequency response of the transmitter inside the soil, an experimental programme is designed to measure, for the first time, the responses of BEs placed inside soil specimens. To capture the transmitter response when placed inside the soil, a transparent granular soil is used to allow penetration of a laser beam from a laser vibrometer. The results show that, contrary to common assumptions, the transmitter response inside the soil specimen is different from the input excitation signal. The time delay between input excitation and transmitter response is found to be a function of frequency and the surrounding medium. Moreover, the vibration modes of BEs are studied by analysing the transmitter response to different input signals. These observations are used to understand the actual behaviour of the BEs placed inside the soil.
Investigating the Influence of Brand Experience and Customer Experiential Values on Building Brand Resonance
Authors: Sharma Alka , Jasrotia Vibhuti , Khajuria Shruti
Published: March 2019

Purpose – The changing dynamics of market and increasing competition have forced the companies to adopt new marketing tools for creating brand differentiation. One such tool that has gained momentum in past few years is brand
experience. Brand experience is critical as there is a drift in the source of value for the customers; they are more experiential in nature. These are known as customer experiential values that are an outcome of positive brand experiences. Customers
with positive brand experiences develop strong emotional associations with the brand. While trying to emotionally connect with the brand through experiences, customers exhibit certain behaviours. These are emotional associations, sense of brand
community, advocacy engagement and loyalty. These strong emotional behaviors that consumers exhibit towards the brands is referred to as brand resonance. Therefore, the aim of this research is to examine the relationships between brand experiences
(BE), customer experiential value (CEV) and brand resonance (BR) among the smartphone users. The study further explores the mediating role of customer experiential value on brand experience and brand resonance relationship.
Impact of the Job Quality on Quality of Life of Employees in the Hospitality Industry
Authors: Khanna Suvidha , Sharma Rahul
Published: March 2019

The job quality is constituted by the set of work features which foster the well-being of the workers. Job quality is directly linked with the consideration of workers’ points of view and this can be found through the
development of surveys into job satisfaction and workers’ well-being Layard, 2005),. The employees in the hotel industry play an important role in the dealing with their customers which has a direct impact upon providing quality services and also
involve a high degree of face-to-face interaction between employees and customers but due to the growing work burden of the employees, they are not able to give ample time to their families. With this background, the objective of the present study is
to evaluate the relationship between job quality and job satisfaction and the effect of job quality and job satisfaction of hotel employees on their overall quality of life. Lastly various measures for the improvement of the quality of life of
employees working in the hotel industry of this particular region are suggested.
Supplemental Data- Detection of Pneumonia Pathogens from Plasma Cell-Free DNA v1
Authors: Langelier Charles
Published: March 2019

Culture-confirmed bacteremia occurs in only a fraction of pneumonia cases, however the degree to which microbial DNA circulates in blood of patients with pneumonia is unknown. Detection of cell-free microbial DNA from plasma is a promising new tool for infectious disease diagnosis. We conducted unbiased metagenomic next-generation sequencing (mNGS) of paired plasma and respiratory fluid from 25subjects, 18with pneumonia (four with concurrent bloodstream infections) and seven with non-infectious respiratory illnesses. Cell-free plasma mNGS identified one or more culture-confirmed bacterial or fungal pathogens in 72% of patients with pneumonia, compared to 100% for respiratory mNGS. In two patients who developed probable ventilator-associated pneumonia (VAP), plasma mNGS afforded early detection of the eventual culture-confirmed VAP pathogens. Our findings suggest that in a majority of patients with severe pneumonia, circulating microbial DNA from confirmed respiratory pathogens can be detected in the bloodstream, even in the setting of negative blood cultures.
Death-related expressions in Javanese angkating layon speech and English eulogy
Authors: Munandar Aris
Published: March 2019

Cultures hold different perceptions of death and demonstrate different linguistic behaviors when performing funeral rituals. This article compares angkating layon speech in Javanese society and eulogies in American society focusing on the use of death-related expressions to reveal their rhetorical function and significance in articulating the two societies’ perception toward death. The data are collected from ten angkating layon speech texts recorded from actual funeral ceremonies and ten eulogy texts downloaded from the internet. Conceptually, this article applies Kunkel's and Dennis's (2003) idea of eulogical rhetoric and Lakoff's andJohnson's (1980) theory of conceptual metaphor. The findings show that both societies conceptualize death into DEATH IS A JOURNEY and DEATH IS REST.  Angkating layon speech is an allusion for sincere acceptance of death, uses less elaborate positive euphemism as a brief report of the deceased’s good characters, and evokes empathy and sincere prayer for the deceased. Meanwhile, a eulogy is a means of maintaining togetherness between the dead and the living, uses elaborate positive euphemism to create a good impression of the eulogized, and thus, appeals more strongly to the memory of the living. It concludes that the Javanese are open about the dead body, create such euphemisms as almarhum(ah), layon/jenazah, and swargito mark the dead as 'other' suggesting that he/she is no longer part of the society, and readily accept a permanent separation from the dead.  On the contrary, Americans are reluctant to mention the dead body, deny separation from the dead, and use almost non-existent lexical marker 'late' signifying death as another episode of life that never affects their relationship with the deceased.
Task, formulaic language, and role play for developing ESL students’ academic language
Authors: Rajeswaran Chandrasena Mandalasamy
Published: March 2019

The effectiveness of task, formulaic language, and role play in facilitating uninhibited communication of ESL learners is beyond doubt. This quantitative empirical research employed a role play communicative assessment and a writing assessment to assess the efficacy of the combination of task, formulaic language, and role play, as a language learning strategy to teach cognitive academic language in English for Specific Purpose classroom of a university. The language ability acquired through brainstorming and reading sessions equipped the students for the task of describing a two-wheeler. The task which made use of the formulaic language led the engineering students to interact meaningfully and know the content for describing a two-wheeler and write the description in a coherent paragraph. The stimulated usage of academic language in a role play could scaffold the content and language learnt for successful retention for effective Oral Academic Presentation (OAP). Although the results cannot be generalised, students joining higher education in universities in ESL/EFL countries would be immensely benefitted by this kind of teaching method.
The use of politeness strategies in the classroom context by English university students
Authors: Mahmud Murni
Published: March 2019

Politeness still becomes a major concern in English language teaching. It is considered as one way to maintain effective classroom interaction. Therefore, as one of the important actors in the class, teachers, and students need to practice politeness as a way to create effective classroom interaction. This study aims to explore the politeness strategies of English students at one of the universities in Makassar. The researcher applied a descriptive qualitative research method to explore the politeness phenomena in EFL classroom interaction. The participants of this research were two classes of English literature program consisting of 50 students. The primary sources of data were the individual student presentations which had been recorded. There were fifty transcriptions of the recording which lasted for five to seven minutes for each presentation. The transcriptions were analyzed and discussed based on the theory of politeness of Brown and Levinson (1987). The findings from this study revealed that English students used different kinds of expressions to encode their politeness in the class. Those expressions were in the forms of greetings, thanking, addressing terms, apologizing, and fillers. There were also some terms derived from students’ vernacular language which were used as a softening mechanism for their presentation. These expressions were categorized as positive and negative politeness. The findings of this study might be used as an input for teachers and students in an effort to create effective classroom interaction.
How language teachers perceive information and communication technology
Authors: Djiwandono Patrisius Istiarto
Published: March 2019

The digital technology has permeated almost every aspect of life. Meanwhile, the responses from the field of language teaching in Indonesia to this new development have been scarce. The paper aims to provide an answer to the question whether language teachers perceive Information and Communication Technology (ICT) as a threat or a helpful assistant. To achieve this, a survey was conducted to 110 English teachers in Java, Indonesia. Five closed-ended items and two open-ended items in an online questionnaire asked them several questions about what conditions they see as threats, how they perceive ICT, and what digital facilities they have been using in their work. The results show that most of them perceived ICT positively, seeing it as a beneficial rather than threatening force. To them, ICT has been an attractive source that provides learning resources, fosters communication and collaboration, and spices up teaching-learning activities. Those who expressed their worry over ICT mentioned the importance of teachers’ upgrading their ICT skills and called for institutional support for the teachers. Three models, TAM (Technological Acceptance Model), UTAUT (Unified Theory of Acceptance and Use of Technology), and TPACK (Technological Pedagogical Content Knowledge) were then discussed to address the need for helping teachers adapt to the fast-changing digital technology.
How do students become self-directed learners in the EFL flipped-class pedagogy? A study in higher education
Authors: Zainuddin Zamzami , Habiburrahim H. , Muluk Safrul , Keumala Cut Muftia
Published: March 2019

The purpose of this study was to identify the impact of implementing a Learning Management System (LMS) ‘TES BlendSpace’ to promote students’ self-directed learning in EFL flipped-class instruction. For the data collection procedure, an individual interview with ten undergraduate students from an Indonesian college was conducted to demonstrate the potential impacts of the LMS in students’ self-directed learning abilities. The observation of students’ learning activities on the TES BlendSpace was also recorded to support the interview data. The LMS was adopted to distribute and receive information. Thus, the students were able to monitor learning activities, learn the contents before coming to class, evaluate the learning process, and interact with others outside of class hours. The finding of this study suggests that the LMS TES BlendSpace is recommended to be performed in teaching EFL for higher education in Indonesia. It offers students’ occasion to practice and enhances their listening, writing, reading and vocabulary skills in and out-of-class times. It also prepares students to get ready for classroom activities in terms of conversations and speaking skills. The further use of the LMSs should become often-visited sites by students for learning activities and replacing other non-educational favorite websites. The finding of this study indicates that the students’ online culture was predominantly formed by the interesting contents posting on the LMS, especially the video lectures and an easy way to use. Additionally, instructors should develop activities in and around the LMS with a number of benefits and rewards. Hence, the students will be motivated to log in the LMS for learning purposes.
PENGARUH PROGRAM PENGALAMAN LAPANGAN TERHADAP PENINGKATAN KOMPETENSI GURU PADA MAHASISWA PROGRAM PENDIDIKAN AKUNTANSI
Authors: Samlawi Faqih
Published: March 2019

PENGARUH PROGRAM PENGALAMAN LAPANGAN TERHADAP PENINGKATAN KOMPETENSI GURU PADA MAHASISWA PROGRAM PENDIDIKAN AKUNTANSI
PENGARUH PROFITABILITAS TERHADAP HARGA SAHAM PADA PT TELEKOMUNIKASI INDONESIA TBK
Authors: Mulyadi Ajang
Published: March 2019

PENGARUH PROFITABILITAS TERHADAP HARGA SAHAM PADA PT TELEKOMUNIKASI INDONESIA TBK
PENGARUH KONSERVATISME TERHADAP ASIMETRI INFORMASI (STUDI EMPIRIS PADA PERUSAHAAN MANUFAKTUR DI BEI)
Authors: Yulia Aida
Published: March 2019

The purpose of this study was to determine the effect of accounting conservatism on information asymmetry in the annual reports of companies listed on the Indonesia Stock Exchange.Target population in this study is a manufacturing company listed on the Indonesia Stock Exchange (BEI) with year observations from 2009 to 2011 the number of companies by 23 companies.Of accounting conservatism measurements conducted on 23 companies, the population of the obtained results of all companies that meet more than one measurement assumptions of accounting conservatism with market value to book value ratio greater than 1, so that the company can be classified as a conservative company. From the test results it can be concluded that the regression coefficient of determinant (R2) value 0.240 indicates that accounting conservatism is able to affect the asymmetry of information in the annual reports of companies listed on the Indonesia Stock Exchange amounted to 24.0 percent and the remaining 76.0 percent is influenced by other variables outside of the research model. Piecemeal evidence suggests that accounting conservatism variable regression coefficient of -0.474, (β ≠ 0), meaning that in partial accounting conservatism and significant negative effect of the information asymmetry in the annual reports of companies listed on the Indonesia Stock Exchange. Refers to the requirement that the results of the study reject Ho and accept Ha.  Keywords: Accounting Conservatism and Information Asymmetry
PENGARUH KECERDASAN EMOSIONAL DAN MINAT BELAJAR TERHADAP PRESTASI BELAJAR (KASUS PADA MAHASISWA PENDIDIKAN AKUNTANSI UNIVERSITAS PENDIDIKAN INDONESIA BANDUNG)
Authors: Wahyuni Shinta
Published: March 2019

Penelitian ini bertujuan untuk mengetahui pengaruh kecerdasan emosional dan minat belajar terhadap prestasi belajar mahasiswa Pendidikan Akuntansi UPI Bandung. Penelitian ini menggunakan metode survey dengan desain penelitian korelasional. Pengumpulan data dilakukan dengan menggunakan angket yang telah diuji validitas dan reliabilitasnya. Data diolah dengan menggunakan statistik parametrik dengan teknik analisis regresi multiple. Penarikan kesimpulan hasil penelitian menggunakan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa kecerdasan emosional dan minat belajar memiliki pengaruh positif terhadap prestasi belajar mahasiswa. Implikasi dari hasil penelitian yang disarankan peneliti adalah bahwa para mahasiswa harus dapat lebih mengendalikan emosinya dan lebih mandiri dalam belajar untuk memperoleh prestasi belajar yang lebih baik. Kata Kunci : Kecerdasan Emosional, Minat  Belajar, Prestasi Belajar, Indeks Prestasi Kumulatif (IPK)
PENGARUH PENGGUNAAN MEDIA PEMBELAJARAN TERHADAP MOTIVASI BELAJAR SISWA PADA MATA PELAJARAN AKUNTANSI
Authors: Mulyadi Ajang
Published: March 2019

Penelitian ini berawal dari sebuah fenomena yang terjadi di SMA Negeri 18 Bandung, dimana motivasi belajar siswa pada mata pelajaran Akuntansi bisa dikatakan rendah. Hal ini ditunjukkan oleh sebuah data awal berupa data absensi siswa kelas XI IPS pada mata pelajaran Akuntansi. Terdapat banyak hal yang dapat mempengaruhi motivasi belajar siswa. Dalam penelitian ini, peneliti berfokus pada salah satu faktor yang mempengaruhi motivasi belajar, yaitu penggunaan media pembelajaran. Penelitian ini bertujuan untuk mengetahui gambaran mengenai penggunaan media pembelajaran dan motivasi belajar siswa kelas XII IPS di SMA Negeri 18 Bandung. Selain itu, penelitian ini juga bertujuan untuk mengetahui bagaimana pengaruh penggunaan media pembelajaran terhadap motivasi belajar siswa kelas XII IPS di SMA Negeri 18 Bandung. Metode yang digunakan pada penelitian ini adalah metode survey verifikatif. Populasi dalam penelitian ini adalah siswa kelas XII IPS sebanyak 140 siswa. Sampel yang diambil sebanyak 104 siswa. Teknik pengambilan sampel yang digunakan adalah teknik simple random sampling. Data mengenai penggunaan media pembelajaran dan motivasi belajar siswa didapatkan dengan menyebarkan angket. Pengujian statistik yang digunakan dalam penelitian ini, yaitu uji normalitas data, uji linieritas, analisis korelasi, uji determinasi dan uji signifikansi. Perhitungan statistik tersebut dibantu dengan software SPSS v.16 for Windows. Gambaran penggunaan media pembelajaran berdasarkan persepsi siswa berada pada kategori cukup, yaitu sebesar 65,38%. Sedangkan motivasi belajar siswa menurut persepsi siswa berada pada kategori cukup pula dengan nilai sebesar 58,65%. Hasil penelitian menunjukkan bahwa penggunaan media pembelajaran berpengaruh positif terhadap motivasi belajar siswa pada mata pelajaran Akuntansi. Hasil penelitian ini telah diuji dan diterima kebenarannya dengan tingkat kepercayaan 95%. Hal ini dibuktikan dengan nilai korelasi sebesar 0,453 dan koefisien determinasi sebesar 0,205. Hal ini berarti bahwa penggunaan media pembelajaran mempengaruhi motivasi belajar siswa pada mata pelajaran Akuntansi sebesar 20,5%. Sedangkan sisanya sebesar 79,5% dipengaruhi oleh faktor lainnya.  Kata Kunci : Penggunaan Media Pembelajaran, Motivasi Belajar Siswa
PENGARUH PENDAPATAN BUNGA TERHADAP PROFITABILITAS PADA PT. BANK JABAR BANTEN
Authors: Mulyani Heni
Published: March 2019

Penelitian ini mengkaji fenomena kinerja profitabilitas (ROA) pada PT. Bank Jabar Banten. Salah satu faktor yang mempengaruhi profitabilitas adalah pendapatan bunga. Pendapatan bunga merupakan pendapatan terbesar yang diterima bank dari kegiatan operasionalnya. Penelitian ini bertujuan untuk mengetahui pengaruh pendapatan bunga terhadap profitabilitas pada PT. Bank Jabar Banten. Penelitian ini menggunakan metode deskriptif verifikatif. Sumber data yang digunakan berupa data laporan keuangan publikasi triwulan PT. Bank Jabar Banten periode Maret 2003 sampai dengan Desember 2010 yaitu neraca dan laporan laba/rugi yang merupakan data sekunder. Untuk menganalisis data penelitian, digunakan  regresi linier sederhana. Berdasarkan hasil analisis regresi linier sederhana diperoleh persamaan Ŷ = 0,91 + 1,10X, dari persamaan tersebut dapat disimpulkan bahwa pendapatan bunga mempunyai pengaruh positif terhadap profitabilitas, dimana setiap kenaikan pendapatan bunga akan mengakibatkan kenaikan profitabilitas (ROA) sebesar 1,10 kali, sebaliknya apabila terjadi penurunan pendapatan bunga maka akan mengakibatkan penurunan profitabilitas (ROA) sebesar 1,10 kali. Kata Kunci: Pendapatan bunga, profitabilitas bank
PENGARUH MANAJEMEN PERSEDIAAN DAN MANAJEMEN PIUTANG TERHADAP MODAL KERJA PERUSAHAAN (STUDI KASUS PADA PERUSAHAAN MANUFAKTUR SEKTOR INDUSTRI BARANG KONSUMSI YANG TERDAFTAR DI BEI)
Authors: Azizah Siti Wily
Published: March 2019

Penelitian ini bertujuan untuk mengetahui pengaruh  manajemen persediaan dengan indikator perputaran persediaan (ITO) dan manajemen piutang dengan indikator perputaran piutang (RTO) terhadap modal kerja perusahaan. Objek pada penelitian ini adalah perusahaan manufaktur sektor industri barang konsumsi yang terdaftar di BEI selama 5 tahun dengan total 100 data observasi. Metode penelitian yang digunakan adalah metode deskriptif dan verifikatif. Adapun teknik pengumpulan data yang digunakan adalah studi dokumentasi terhadap laporan neraca dan laporan laba rugi perusahaan manufaktur sektor industri barang konsumsi yang terdaftar di BEI. Analisis statistik yang digunakan dalam penelitian ini adalah teknik analisis regresi linier berganda untuk data panel dengan bantuan aplikasi EViews 8. Berdasarkan pengujian diperoleh hasil bahwa secara simultan manajemen persediaan dan manajemen piutang berpengaruh negatif terhadap modal kerja perusahaan. Secara parsial, manajemen persediaan berpengaruh negatif signifikan terhadap modal kerja perusahaan, sedangkan manajemen piutang berpengaruh negatif tidak signifikan terhadap modal kerja perusahaan.  Kata kunci : Manajemen persediaan, manajemen piutang, modal kerja perusahaan, perputaran persediaan, perputaran piutang.
APLICAÇÃO DE BIOFERTILIZANTE DE BOVINOCULTURA LEITEIRA EM UM PLANOSSOLO
Authors: Maciel Alyne Martins , Silva Jonathas Batista Gonçalves , Nascimento Andressa de Matos , Paula Vanessa Romario de , Otenio Marcelo Henrique
Published: March 2019

Dejetos de bovinos contêm quantidades significativas de nitrogênio e fósforo. Por isso, o manejo inadequado dos mesmos pode causar eutrofização dos corpos de água e poluição do solo. Porém, o correto manejo destes resíduos estabilizados traz benefícios ao solo, à cultura e possibilita a redução do uso de fertilizantes químicos convencionais. Este trabalho avaliou os efeitos da aplicação do biofertilizante proveniente da Água Residuária de Bovinocultura (ARB) leiteira nas características químicas e físicas de um Planossolo. O trabalho foi realizado no campo experimental da EMBRAPA Gado de Leite, localizado em Coronel Pacheco (MG). Foram aplicadas quatro doses (0, 10, 20 e 30 kg ha-1 de N) de biofertilizante e adubo NPK 30-00-20 em cultura de milho. Nas camadas de 0 a 20 cm de profundidade de solo foram avaliados: pH, textura, densidade, condutividade elétrica, matéria orgânica (MO), capacidade de troca catiônica efetiva (CTCt) e potencial (CTCT), soma de bases (SB), saturação por alumínio (m) e por bases (V), teores trocáveis de Ca, K, Mg, N e disponível de P. As doses de biofertilizante de ARB proporcionaram o mesmo efeito da adubação convencional no solo, no que se refere aos teores de macronutrientes, micronutrientes e índices de fertilidades. Os resultados indicam que é possível substituir parcialmente a adubação nitrogenada convencional por biofertilizante de ARB.
ANÁLISE DE SUSTENTABILIDADE DA ÁREA RURAL DO MUNICÍPIO DE TRIUNFO (PE)
Authors: Gonçalves Bárbara Denise Ferreira , Vital Tales Wanderley
Published: March 2019

Este trabalho investiga o desenvolvimento rural sustentável de Triunfo (PE), com o objetivo de verificar se esse tipo de desenvolvimento vem ocorrendo no município e com que intensidade. Para isso, foi tomado como referência o modelo de Sachs, que considera a sustentabilidade no meio rural a partir das dimensões social, ecológica e econômica. A esse modelo teórico de desenvolvimento sustentável foram incorporados indicadores de sustentabilidade do IBGE, resultando na elaboração de um modelo analítico, que foi aplicado utilizando dados obtidos nos levantamentos realizados. Como resultado, observou-se para o meio rural de Triunfo (PE) grande dependência das políticas públicas, principalmente aquelas dirigidas à agricultura familiar, como principal apoio aos residentes da área rural. Foi identificado que a sustentabilidade desse meio rural está em andamento devido ao fato de que a maioria dos pequenos produtores, em razão das secas ocorridas, não tem conseguido manter ou ampliar as atividades produtivas de suas unidades de produção, nem incorporar práticas ecologicamente corretas. Contudo, socialmente essa área rural, devido à ação de entidades religiosas, sindicais e da sociedade civil, tem um perfil diferenciado de empoderamento das comunidades rurais. Conclui-se que as ações de sustentabilidade econômica, ambiental e social estão em processo de construção no município, e são assimétricas e de baixa intensidade.
NÚMERO DE FOLHAS E BOKASHI NA BROTAÇÃO E CUSTOS DE PRODUÇÃO DE MUDAS DE Schinus terebinthifolius Raddi. POR ESTAQUIA
Authors: Santos Cleberton Correia , Leite Luiz Felipe Balbueno , Silva Orivaldo Benedito da , Torales Elissandra Pacito , Heredia Zárate Néstor Antonio , Vieira Maria do Carmo
Published: March 2019

Schinus terebinthifolius Raddi. (pimenteira rosa, Anacardiaceae) é utilizada devido às suas propriedades medicinais e condimentares, com valor agregado no mercado. Apesar disso, há poucos estudos relacionados à propagação vegetativa e custos de produção de mudas da espécie. O objetivo deste trabalho foi avaliar a presença de folhas e uso de bokashi na propagação vegetativa da pimenteira rosa. Avaliaram-se três tipos de estacas caulinares com 0, 1 ou 2 folhas, sem e com adição de bokashi (10 g kg-1) ao substrato, sob sombrite 50%. O arranjo experimental foi em esquema fatorial 3x2, no delineamento de blocos casualizados, com quatro repetições. As maiores porcentagens de brotações foram observadas em estacas sem folhas, sem bokashi (50,0%), aos 35 e 42 dias após o estaqueamento (49,3% e 47,2%, respectivamente); o maior índice de velocidade de brotação foi nas estacas sem folhas (0,5766) e o maior comprimento de brotos (24,37 cm) foi observado com a adição de bokashi ao substrato. Os custos de produção variaram entre R$ 232,07, entre o maior (R$ 2.428,66) com bokashi e o menor (R$ 2.196,59), sem bokashi. A quantidade de folhas e uso de bokashi influenciaram na propagação por estaquia e custos na produção de mudas de pimenteira rosa.
PALHA DE VARIEDADES DE SORGO NA FORMULAÇÃO DE NOVOS COMPOSTOS PARA O CULTIVO DO COGUMELO Pleurotus ostreatus
Authors: Siqueira Otavio Augusto Pessotto Alves , Martins Olívia Gomes , Andrade Meire Cristina Nogueira de
Published: March 2019

Pleurotus ostreatus é um cogumelo comestível cujo cultivo pode ser realizado em diferentes resíduos como substrato, porém pouco se sabe sobre a utilização do sorgo para sua produção. Objetivou-se neste estudo analisar a viabilidade do sorgo para o cultivo de P. ostreatus. Foram testados três tratamentos, C1 (testemunha, palha de cana-de-açúcar), C2 (sorgo biomassa) e C3 (sorgo sacarino). Os tratamentos foram submetidos a processo de compostagem e pasteurização e após o resfriamento dos compostos foi realizada a inoculação de P. ostreatus. A incubação e colheita foram realizadas durante 2 meses, seguidas de análise nutricional dos cogumelos e análise química dos compostos. Foram avaliados eficiência biológica, perda de matéria orgânica e massa de basidiomas frescos. Não houve diferença significativa entre os tratamentos, segundo análise química dos substratos, exceto para o teor de umidade, em que o tratamento testemunha foi inferior aos demais. Quanto à produtividade, os tratamentos apresentaram os seguintes resultados: C1: 1,73 kg; C2: 1,34 kg; e C3: 1,07 kg. Não houve diferença significativa para a eficiência biológica entre os tratamentos C1 e C2, com valores de 69,80% e 72,76% respectivamente, enquanto o tratamento C3 apresentou a menor eficiência biológica (51,72%). A perda de matéria orgânica foi de 50,56%, para C1, 44,50% para C2 e 40,16% para C3. A análise nutricional dos cogumelos não demonstrou diferença significativa entre os tratamentos, exceto para o teor de fibra bruta, onde o tratamento C3 foi superior com 18,95%, seguido pelo tratamento C2 com 16,40% e o testemunha com 14,95%.
Saliva- A Tool for Diagnosis in Periodontal Disease
Authors: Abiramidevi M. , Nagappan Visalakshi , Prasad P. Arun Kumar
Published: March 2019

Periodontitis, a chronic inflammatory condition involving tooth supporting structures that results in connective tissue loss and progressive bone loss. Careful diagnosis and treatment plan is inevitable for the successful clinical outcome. Investigation of biomarkers specific to certain periodontal disease in saliva gains more clinical interest in the present era. The gratification towards saliva has been increased over GCF due to its ease and non-invasive methods of collection compared to GCF. Saliva contains numerous biomarkers which is an emerging chair side diagnostic tool that will play a major role for the future investigators. This article aims at reviewing the biomarkers present in the saliva pertaining to particular periodontal diseases and its activity.
Effects of Coconut and Olive Oil on Tooth and Restoration – in vitro Study- Myth(oil)ogy?
Authors: Saravanan Vanashri , Kumar Vaanishree M. , Thentamil A. , Jacob Mathew
Published: March 2019

One of the natural and traditional methods adopted for obtaining whiter teeth is oil pulling. This is a simple and cost efficient method which has been used for decades and advised for overall maintenance of oral hygiene. However, there have been contradicting results regarding the efficacy of oil pulling on tooth whitening in previous studies. In this study, natural teeth (premolar teeth) were collected and divided into four groups and preserved in different mediums for 24 hours for a period of seven days to study the effects on hard tissue enamel. The teeth were observed every 24 hours and the difference in tooth whitening was compared using a tooth shade guide and evaluated for observable changes in colour.
Magic and Modernity
Authors: Veen Frank Bouman-van
Published: March 2019

Witchcraft and magic are often presented as ‘a thing of the past’, as irrational remnants of a less civilized age from which modern man has distanced himself. This claim is deceiving, however, for magic remains deeply rooted in modern society and cannot be so easily dismissed. David Martin and Peter Geschiere discuss the complex concepts of witchcraft and magic, presenting them in a manner that is both accessible and innovative. They offer alternatives as to how these concepts can be approached and studied, and indicate how future research can benefit from more accurate and at the same time less refined definitions of witchcraft and magic.
МАТЕМАТИЧНА МОДЕЛЬ ВИЛУЧЕННЯ ПРОДУКТІВ ЗНОШУВАН-НЯ В ТРИБОСИСТЕМАХ З ТЕКСТУРОВАНИМИ ЛУНКОВИМИ ПОВЕРХНЯМИ
Authors: Марчук Володимир Єфремович , Морозов Володимир Іванович , Крисак Яків Васильович
Published: March 2019

Запропоновано математичну модель умови вилучення продуктів зношування у дискретні ділянки в трибосистемах з текстурованими лунковими поверхнями. Встановлено зростання індукції магнітного поля кромок дискретних ділянок при зменшенні коефіцієнта q і навпаки, що підтверджується експериментальними дослідженнями.
МОДЕЛЮВАННЯ ТЕЧІЇ НА ПЛАСТИНІ З ВІДСМОКТУВАННЯМ ПОГРАНИЧНОГО ШАРУ
Authors: Терещенко Юрій Юрійович , Терещенко Юрій Матвійович , Дорошенко Катерина Вікторівна
Published: March 2019

При течії газу в каналі при обтіканні тіл різної форми на стінках утворюється пограничний шар, викликаний наявністю сил тертя. Відсмоктування невеликої кількості загальмованого у стінки газу є одним із засобів ламінаризации течії в пограничному шарі і зменшення тертя. У роботі ставиться завдання оцінити вплив форми вхідних кромок дискретних каналів на ефективність відсмоктування пограничного шару на пластині. Поставлена задача вирішувалася методом чисельного моделювання. Розрахунок течії на пластині проводився за допомогою усереднених по Рейнольдсу рівнянь Нав'є-Стокса. Для замикання рівнянь використовувалася модель турбулентної в'язкості SST Ментера. Для урахування пограничного шару розрахункова сітка мала адаптацію. Тип розрахункової сітки - неструктурована. На вході задавалася осьова швидкість 100 м/с. Об'єкт дослідження - пластина довжиною 100мм. На пластині виконано 15 дискретних каналів для управління пограничним шаром, ширина яких 1 мм, відстань між каналами 3 мм. Для дослідження обрані дві форми каналів: з прямокутними вхідними кромками і з профільованими вхідними кромками. Інтенсивність управління пограничним шаром оцінювалася коефіцієнтом відсмоктування. Першим етапом роботи був розрахунок течії на пластині без використання управління пограничним шаром. В ході наступного етапу роботи були проведені серії газодинамічних розрахунків течії на пластині з використанням відсмоктування пограничного шару при різній інтенсивності. Результати розрахунків показали, що форма вхідної кромки каналів для відсмоктування пограничного шару не істотно впливає на ефективність управління пограничним шаром. При прямокутних вхідних кромках каналів для управління пограничним шаром товщина пограничного шару зменшується на 58...65%, при профільованих вхідних кромках ефективність зростає до 63...70%.
Immunomodulatory potential of gut microbiome-derived short-chain fatty acids (SCFAs)
Authors: Ratajczak Weronika , Rył Aleksandra , Mizerski Arnold , Walczakiewicz Kinga , Sipak Olimpia , Laszczyńska Maria
Published: March 2019

Intestinal microbiota is an element of the bacterial ecosystem in all mammalian organisms. These microorganisms play a very important part in the development, functioning, and modulation of the immune system from the moment of birth. In recent years, owing to the use of modern sequencing techniques, the microbiome composition in healthy people has been identified based on bacterial 16S rRNA analysis. Currently, more and more attention is being given to the influence of microorganisms on the host’s cellular metabolism. Analysis of microbial metabolites, among them short-chain fatty acids (SCFAs), and disruption of intestinal microbiota homeostasis in terms of their effects on molecular regulatory mechanisms of immune reactions will surely improve the understanding of the etiology of many common diseases. SCFAs, mainly butyrate, propionate, and acetate, occur in specific amounts, and their proportions can change, depending on the diet, age and diseases. The levels of SCFAs are substantially influenced by the ratio of commensal intestinal bacteria, the disturbance of which (dysbiosis) can lead to a disproportion between the SCFAs produced. SCFAs are regarded as mediators in the communication between the intestinal microbiome and the immune system. The signal they produce is transferred, among others, in immune cells via free fatty acid receptors (FFARs), which belong to the family of G protein-coupled receptors (GPCRs). It has been also confirmed that SCFAs inhibit the activity of histone deacetylase (HDAC) – an enzyme involved in post-translational modifications, namely the process of deacetylation and, what is new, the process of histone crotonylation. These properties of SCFAs have an effect on their immunomodulatory potential i.e. maintaining the anti/pro-inflammatory balance. SCFAs act not only locally in the intestines colonized by commensal bacteria, but also influence the intestinal immune cells, and modulate immune response by multi-protein inflammasome complexes. SCFAs have been confirmed to contribute to the maintenance of the immune homeostasis of the urinary system (kidneys), respiratory system (lungs), central nervous system, and the sight organ.
Invited Speakers
Authors: Speakers Invited
Published: March 2019

No abstract is available for this article.
Effects of Benzo(a)pyrene on the endometrial receptivity and embryo implantation in mice: An experimental study
Authors: Mardanshahi Zeinab , Karimpour Abbasali , Talebpour Amiri Fereshteh , Valadan Reza
Published: March 2019

Background: Benzo(a)pyrene (BaP) as an environmental pollutant is ubiquitous in the environment and it has destructive effects on human health. So far, various studies have demonstrated that BaP can cause adverse effects on the female reproductive system, but the existing information is limited about the effects of BaP on the endometrial receptivity and embryo implantation.
Objective: The aim of this study was to investigate the effects of BaP on the endometrial receptivity and implantation in mice.
Materials and Methods: In this experimental study, 40 pregnant BALB/c mice were divided into 5 groups (n = 8/each) as follows: experimental groups received the doses of 100 μg/kg, 200 μg/kg, and 500 μg/kg BaP dissolved in corn oil, the control group received normal saline and sham group received corn oil. Pregnant mice administered these solutions from Day 1 to Day 5 of gestation by gavage. On Day 6, the mice were sacrificed. Then their embryos were counted and the hormonal, histomorphological and molecular analyses were performed on themocusa of uterine tube.
Results: The data revealed that BaP reduces estrogen and progesterone levels, decreases the number of implantation site, endometrium thickness, uterine lumen diameter, stromal cells and endometrial glands, and blood vessels in the endometrium. However, the expression of Activin receptor-like kinase 5 and E cadherin genes was not changed by BaP with different doses.
Conclusion: The finding of this study showed that BaP can change estrogen and progesterone levels, and endometrial morphology leads to impairing the endometrial receptivity and decreasing the number of implantation site.
Key words: Benzo(a)pyrene, Embryo implantation, Estrogen, Progesterone, ALK5, E-cadherin.
Sexual and reproductive healthcare needs of Iranian men: A cross-sectional study
Authors: Javadnoori Mojgan , Hajizadeh Marjan , Javadifar Nahid , Hossein Haghighizadeh Mohammad
Published: March 2019

Background: The sexual and reproductive health (SRH) needs of men have received little attention in Iran’s healthcare system. Developing appropriate strategies to meet men’s needs requires careful assessment and recognition of their health needs.
Objective: The objective of this study is to assess men’s SRH needs and satisfaction with received services.
Materials and Methods: This descriptive cross-sectional study was conducted with 1068 adult men aged between 20 and 60 years in Ahvaz in 2014. For obtaining the SRH services needs of men, in addition to the self-reported felt needs, expressed needs and unmet needs, a need assessment was also done using a questionnaire that was developed for the research; its validity and reliability were assessed.
Results: The men’s perceived, expressed and unmet needs for SRH services were, priority-wise, screening and diagnosis of male genital cancers (63.3%), receiving contraceptive methods (36%), diagnosis, and treatment of male sexual dysfunction (86.9%), respectively. Preventing sexually transmitted disease/AIDS (72.1%), using contraceptives correctly (39.5%), and resisting peer pressure (86.6%) were, respectively, the first felt, expressed, and unmet skills men needed. The results of multivariate logistical regression showed that there was a significant statistical correlation between men’s SRH needs and their socio-demographic factors (age, marital/educational status, income) (p < 0.05).
Key words: Reproductive health, Needs assessment, Men.
Europa, vía pedagógica: la viabilidad del Humanismo en época postmoderna
Authors: Vilanou Torrano Conrad
Published: March 2019

En este artículo se presenta Europa como una historia narrada que ha recurrido a la pedagogía para transmitir sus valores. Desde esta perspectiva, Europa constituye un proyecto que se enraíza en la cultura clásica y que, a través del cristianismo, ha llegado a la modernidad gracias a los ideales de formación. Asimismo, se constata que la idea de Europa —entendida como un sistema axiológico— ha seguido un devenir dialéctico, de modo que a épocas en que han prevalecido los principios humanistas han seguido etapas en que han dominado los intereses económicos. Con la llegada de la crisis de 2008, parece que los valores humanistas que han dado sentido a la historia de Europa han quedado afectados, de modo que conviene garantizar la viabilidad del humanismo —esto es, la defensa de la dignidad humana— como un valor prioritario, a pesar de las incertidumbres que acechan al proyecto europeo en un mundo postmoderno.Recibido: 02 julio 2018 Aceptado: 06 septiembre 2018 Publicación en línea: 27 febrero 2019
El Derecho Comunitario de los contratos públicos: un pilar infravalorado de la superación de los nacionalismos y de construcción de la identidad europea
Authors: Gosálbez Pequeño Humberto
Published: March 2019

Desde la adhesión de España a las Comunidades Europeas en 1986, la legislación española de contratos públicos acepta el principio de no discriminación por la nacionalidad, abandonando el proteccionismo nacional de los contratistas presente en la legislación española. La Ley 9/2017 de Contratos del Sector Público consolida ese proceso histórico de adaptación de la legislación española de contratos públicos. En el Derecho europeo de los contratos públicos aparece una identidad europea, una «nacionalidad europea» de los contratistas nacionales de los Estados miembros.Recibido: 02 julio 2018 Aceptado: 16 julio 2018 Publicación en línea: 27 febrero 2019
The European Identity Rationale in the EU Free Trade Agreements: Economic rather than Cultural Objectives?
Authors: Chochorelou Maria
Published: March 2019

In recent years, we can observe an increase of the EU Free Trade Agreements (FTAs) addressing cultural matters. The focus of the Union seems to lie on the audiovisual services sector, which is excluded by the scope of all these Agreements. This so-called ‘cultural exception’ clause does not apply to other cultural sectors, which are however still regulated in EU FTAs. The regulation takes the form of either commitments and reservations made by the Parties to a specific sector, or cooperative provisions mainly found in the Protocols of Cultural Cooperation supplementing some EU FTAs. Although not explicitly mentioning culture, other EU FTA Chapters, such as Subsidies and Intellectual Property, also entail cultural considerations. Rhetorically, the EU has considered the inclusion of cultural aspects into its FTAs as a tool to protect and promote the European identity and cultural diversity. However, both the negotiations as well as the texts of these Agreements illustrate that the motives behind this exclusion are mainly economic and political.Received: 02 July 2018 Accepted: 16 July 2018 Published online: 27 February 2019
¿Identidad europea o identidades europeas?
Authors: José i Mestre Carles
Published: March 2019

Nos ocuparemos del significado del término «identidad» desde una perspectiva filosófica concernida singularmente con lo político. Así pues, se tratará principalmente de determinar en qué sentido cabe hablar de una identidad política europea, y para ello se esclarecerá en primer lugar lo que signifique la expresión «identidad política». Se defenderá que una identidad política remite por defecto a lo colectivo, y que los límites de una colectividad política específica vienen definidos por un proceso de identificación recíproca entre individuos en relación con hechos típicamente históricos: respeto de un pasado (no necesariamente común), relación cultural en un presente (necesariamente, pues, compartido), y proyección hacia un futuro (a partir de un compromiso individual). Desde este análisis, se expondrá hasta qué punto es pertinente hablar de «identidad europea», y a partir de qué punto conviene más referirnos a «identidades europeas» a partir de la noción de «pueblo», todo ello sin dejar de prestar atención a la cuestión de la forma política.Recibido: 02 julio 2018 Aceptado: 16 julio 2018 Publicación en línea: 27 febrero 2019
Wpływ uwarunkowań geograficzno-przyrodniczych na rozwój małych miast
Authors: Świdyński Jarosław , Świdyńska Natalia Karolina
Published: March 2019

W artykule podjęto się określenia wpływu uwarunkowań geograficzno-przyrodniczych na rozwój małych miast. Badania zostały przeprowadzone na przykładzie wybranych małych miast województwa warmińsko-mazurskiego.