bluuebunny/crossref_metadata_2025 huggingface dataset:
Dificultad de los verbos fraseológicos en inglés para los hispanohablantes
Authors: Calderón Sonia
Published: September 2021

El artículo ofrece un análisis lingüístico de la dificultad que presentan los verbos fraseológicos en inglés para los hispanohablantes, teniendo en cuenta su estructura sintáctica, su función semántica y pragmática y su aspecto fonológico. Como complemento, se propone una guía para la enseñanza de estos verbos y su práctica en clase.This article presents a linguistic analysis of the difficulty of English phrasal verbs for Spanish speakers, including their syntactic structure, their semantic and pragmatic function, and phonological aspects. Guidelines are also given for teaching and practicing these verbs.
Cervantes y el mundo moderno
Authors: Durán Luzio Juan
Published: September 2021

Se analiza el papel desempeñado por la gran novela cervantina en el subsecuente desarrollo de la narrativa moderna hasta la actualidad. La aventura del héroe, en aquella célebre novela, adopta un sentido actual profundamente simbólico, que todavía tiene vigencia, porque apunta a lo conocido, a lo cotidiano, a lo posible.An analysis is carried out on the role of Cervantes' great novel in the subsequent development of modern narrative up to the present time. The adventure of the hero in that famous novel adopts a highly symbolic sense which remains valid because it addresses what can be considered familiar, well known and possible.
Modes of Discourse: A Cross-Cultural Study of Essays Written in English and Spanish by EFL Students in Costa Rica (Part 1)
Authors: Saborío Pérez Ileana
Published: September 2021

Mediante un análisis contrastivo se evalúan los patrones retóricos interculturales desarrollados por estudiantes nativohablantes del español, en el proceso de escritura. Se plantean cinco preguntas de investigación con respecto a las diferencias o similitudes cuando se escribe en español o en inglés, y su influencia en la escritura para el desarrollo del estilo y la estructura oracional, así como sus implicaciones pedagógicas.A contrastive analysis was used to evaluate the cross-cultural rhetorical patterns developed by native Spanish-speaking students, in the writing process. Five research questions were posed with respect to similarities or differences when writing in Spanish or English, and their influence on writing in the development of style and sentence structure, as well as their pedagogical implications.
How Can EFL Students Be Corrected Without Hindering Oral Participation?
Authors: Ramírez Acosta Jimmy
Published: September 2021

Se describen las técnicas que suelen emplearse para corregir la producción oral de estudiantes de segundas lenguas. Según la forma en que los estudiantes son corregidos, así su deseo de participar. Parte de la información proporcionada se fundamenta en una investigación llevada a cabo con un grupo de estudiantes de inglés en cuanto a sus ideas sobre modelos de corrección y sus propuestas.The error correction techniques commonly applied by teachers to improve students' oral output are described here. The way students' output is treated plays an important role in their desire to participate. Part of the information provided is based on research carried out with a group of students of English conceming their ideas about error correction and the techniques that they proposed.
El advenimiento de una nueva realidad en Mujeres, sombras y coloquios de uno, de Eduardo Vargas Ugalde
Authors: Araya Seidy
Published: September 2021

Se indaga sobre las rupturas de los límites que la razón impone a la existencia humana.
L'universe fantastique de Jean Ray
Authors: Boza Araya Virginia
Published: September 2021

Se informa en detalle acerca de los temas y el estilo de los textos fantásticos del escritor belga Jean Ray.
The Uncanny in the Themes of Evil, Transgression and the Double in Nathaniel Hawthorne's "Rappaccini's Daughter"
Authors: Barboza Núñez Esteban
Published: September 2021

El propósito de este artículo consiste en explorar los mecanismos y representaciones de lo siniestro en "La hija de Rappacci" de Nathaniel Hawthome como expresión del mal dentro de los límites del género gótico del siglo XIX; como expresión del tema del doble en tres personajes humanos y en uno no humano que aparecen en el cuento; y como expresión de trasgresión en el personaje principal, Giovanni Guasconte. El concepto de lo siniestro que se usará será el de la teoría psicoanalítica, siguiendo especialmente los aportes de Sigmund Freud y Jacques Lacan. The purpose of this artide is to explore the mechanisms and representations of the uncanny in Nathaniel Hawthome's "Rappaccini's Daughter" as an expression of evil within nineteenth century Gothic boundaries; as an expression of the theme of the double in three human characters and in one non-human component of Rappaccini's garden; and as an expression of transgression in Giovanni Guasconte, the main character. The concept of the uncanny to be used will be that of psychoanalytic theory, especially reliant on the contributions on the topic by Sigmund Freud and Jacques Lacan.
Le monde arabe en filigrane dans l'œuvre de Tahar Ben Jelloun
Authors: Boza Araya Virginia
Published: September 2021

Tahar Ben Jelloun es un escritor marroquí de expresión francesa; sin embargo, su obra está marcada tanto en la forma como en el contenido por la cultura árabe. Desde el nombre de sus novelas el autor clama su origen musulmán. En sus obras el novelista reconstituye las callejuelas de sus medinas por medio de una estructura laberíntica en la que la cultura arabo-musulmana cobra vida gracias a un vocabulario denotativo y connotativo. El autor describe la sociedad tradicional y moderna con lujo de detalles denotándolas y connotándolas por medio de las acciones, los gestos y los intercambios discursivos de sus personajes. Las referencias al Islam como parte integrante de su identidad, a la literatura, a la caligrafía, a los grandes filósofos permiten al lector comprender mejor la religión y las creencias de la sociedad arabomusulmana.Tahar Ben Jelloun est un écrivain marocain d'expression française cependant son œuvre reste foncierement arabe autant dans la forme que dans le fondo. En effet la structure de ses romans emprunte les dédales de ses médinas et la présence de la culture arabo-musulmane y est indiscutable. Des les titres de ses romans l'auteur confirme son appartenance au monde musulman soit par les vocables choisis soit par leur sonorité. L'auteur dépeint la sociétén traditionnelle et la société modeme grace a un réseau de références tant dénotatives que connotatives grace aux actions, aux gestes, aux échanges discursif de ses personnages, aux situations décrites. Les allusions à l'Islam comme une partie indissociable de l'identité, à la littérature, à la calligraphie, aux grands philosophes permettent au lecteur de mieux comprendre la religion et les croyances de la société arabo-musulmane.
The role of the dehydration stage in the post-hypertonic hemolysis of mammalian erythrocytes
Authors:   Institute of Problems of Cryobiology and Cryomedicine NAS of Ukraine, 23 Pereyaslavska str., Kharkiv, 61016, Ukraine, cryo@online.kharkov.ua, Nipot O. E. , Shapkina O. O. ,   Institute of Problems of Cryobiology and Cryomedicine NAS of Ukraine, 23 Pereyaslavska str., Kharkiv, 61016, Ukraine, cryo@online.kharkov.ua, Zubov P. M. ,   Institute of Problems of Cryobiology and Cryomedicine NAS of Ukraine, 23 Pereyaslavska str., Kharkiv, 61016, Ukraine, cryo@online.kharkov.ua, Orlova N. V. ,   Institute of Problems of Cryobiology and Cryomedicine NAS of Ukraine, 23 Pereyaslavska str., Kharkiv, 61016, Ukraine, cryo@online.kharkov.ua, Shpakova N. M. ,   Institute of Problems of Cryobiology and Cryomedicine NAS of Ukraine, 23 Pereyaslavska str., Kharkiv, 61016, Ukraine, cryo@online.kharkov.ua
Published: September 2021

The aim of this study was to assess the level of damage to mammalian erythrocytes under post-hypertonic shock depending on the concentration of NaCl in the dehydration medium and to determine the effect of hypertonic NaCl solutions on the condition of mammalian erythrocytes by flow cytometry. To achieve this goal, spectrophotometric and cytometry research methods were used. The data obtained showed that post-hypertonic lysis of mammalian erythrocytes depends on the concentration of NaCl in the dehydration medium. The most sensitive to the effects of post-hypertonic shock are rat erythrocytes, the least sensitive are rabbit cells. Cytometry studies revealed significant changes in the histograms of the distribution of erythrocytes of all mammalian species with increasing salt concentration in the dehydration medium. These changes are species-specific and are probably related to changes in cell volume and morphology. The data revealed a relationship between the level of post-hypertonic hemolysis and the values of such indicators as the median distribution and the coefficient of variation. Thus, an increase in the sensitivity of mammalian erythrocytes to post-hypertonic shock with increasing salt concentration in dehydration medium was usually accompanied by a decrease in the median cell division, and higher values of the coefficient of variation are characteristic of mammalian erythrocytes resistant to post-hypertonic shock.
Rural development
Authors: Fáziková Mária , Babjaková Barbora , Hrivnák Michal
Published: September 2021

Vidiek je územie, ktoré je organickou súčasťou regionálneho priestoru. Má svoje charakteristické črty, ktorými sú prirodzená krajina so špecifickým využitím najmä odvetviami primárneho sektora, nízka hustota obyvateľstva, rozdrobená sídelná štruktúra, diverzifikovaná ekonomická štruktúra, sociálna kohézia a bohatstvo kultúrnych tradícií. Má však aj problémy vyplývajúce práve z nízkej hustoty obyvateľstva a nízkej intenzity ekonomických aktivít. Vidiecke regióny a vidiecke obce ťažko zachytávajú globálne rozvojové impulzy, dostávajú sa do rozvojových problémov. Vzniká priestorová nerovnováha, ktorá neumožňuje efektívne využívať územný kapitál vidieka a vytvára tlak na verejné zdroje. Rozvoj vidieka je v ekonomickom, sociálnom aj environmentálnom zmysle významnou témou jednotlivých súčastí regionálnej vedy, ale aj ekonomickej a politickej praxe. Autori sa v tejto knihe pokúsili zhrnúť svoje poznatky o faktoroch, procesoch, politikách a nástrojoch týkajúcich sa ekonomického a sociálneho rozvoja vidieka. Predkladaná učebnica načrtáva teoretické východiská, identifikuje rozvojový potenciál ako aj rozvojové problémy vidieka. Naznačuje spôsoby ich riešenia vrátane metodických nástrojov na ich praktické riešenie. Sú to samozrejme rámcové problémy omnoho komplexnejšej problematiky, ktorá je predmetom ďalšieho skúmania. Je určená pre študentov Slovenskej poľnohospodárskej univerzity v Nitre, ktorí študujú predmet „Rozvoj vidieka“, pre študentov iných univerzít a vysokých škôl, ktorých daná problematiky zaujíma, ale aj pre pracovníkov verejnej správy na všetkých úrovniach riadenia.
Regional and local development
Authors: Melichová Katarína , Varecha Lukáš
Published: September 2021

Cieľom učebnice je priblížiť študentom rozdiely medzi regionálnym rastom a regionálnym rozvojom, aby pochopili rôzne interpretácie ekonomického rastu a rozvoja v rôznych teoretických konceptoch a ako sa vyvíjali v priebehu času a ako boli tieto teoretické koncepty premietané do konkrétnych politických opatrení (a prečo niektoré z nich zlyhávajú). Obsahovo ju tvoria tri logické celky. Prvý celok je venovaný vysvetleniu základných pojmov ako je regionálny rast a rozvoj, konceptu regionálnej konkurencieschopnosti a faktorom, ktoré ju ovplyvňujú a príčinám a dôsledkom regionálnych disparít. Druhý najrozsiahlejší celok zase zahŕňa vybrané teoretické a koncepčné prístupy, ktoré vysvetľujú vzájomné pôsobenie faktorov rozvoja a ich súvislosť s regionálnym rozvojom a regionálnymi disparitami. Regionálny rast a rozvoj vysvetľuje z pohľadu neoklasického prístupu, ktorého nedostatky neskôr vyústili do dominancie keynesiánskeho a polarizačného prístupu k regionálnemu rastu a rozvoju. Riešenie nedostatkov týchto zase priniesli neoliberálne a inštitucionálne prístupy, ktoré majú dominantný vplyv na charakter regionálnej politiky aj v súčasnosti. Prečo práve teórie? Lebo svet sám o sebe (a tým aj ekonomický systém), bez toho, aby sme sa naň pozreli, je chaotický. Až naša schopnosť modelového zmýšľania, teda identifikácie opakujúcich sa vzorov, nám umožňuje orientovať sa v ňom. Tieto vzorce sú abstrakciou reality, ktorá nám pomáha zorientovať sa vo svete a ekonomickom systéme tak, aby sme pochopili príčinno-dôsledkové súvislosti prevládajúce v tomto systéme, čo nám umožní vyhnúť sa krokom (napr. politickým rozhodnutiam), ktoré by mohli viesť k nežiaducim dôsledkom a pomôže nastaviť také opatrenia, aby sme zabezpečili spoločensky prijateľný výsledok. Okrem toho, že vysvetľujú „ako funguje svet“, nám teórie rozvoja zároveň poskytujú „recepty“ na tvorbu politík a konkrétnych opatrení na jeho ovplyvňovanie s cieľom dosiahnuť spoločensky žiaduce efekty. Práve tretí celok prináša historický priebeh aplikácie týchto teoretických a koncepčných prístupov v praxi, konkrétne v regionálnej politike Európskej únie. Okrem pojmu teória v učebnici používame aj pojmy koncepcia a model s porovnateľným významom.
Economic Trends of Racial Disparities in Pediatric Postappendectomy Complications
Authors: Mpody Christian , Willer Brittany , Owusu-Bediako Ekua , Kemper Alex R. , Tobias Joseph D. , Nafiu Olubukola O.
Published: September 2021

BACKGROUND

Despite unparalleled advances in perioperative medicine, surgical outcomes remain poor for racial minority patients relative to their white counterparts. Little is known about the excess costs to the health care system related to these disparities.

METHODS

We performed a retrospective analysis of data from the Nationwide Inpatient Sample between 2001 and 2018. We included children younger than 18 years admitted with appendicitis who underwent an appendectomy during their hospital stay. We examined the inflation-adjusted hospital costs attributable to the racial disparities in surgical complications and perforation status, focusing on differences between non-Hispanic white patients and non-Hispanic Black patients.

RESULTS

We included 100 639 children who underwent appendectomy, of whom 89.9% were non-Hispanic white and 10.1% were non-Hispanic Black. Irrespective of perforation status at presentation, surgical complications were consistently higher for Black compared with white children, with no evidence of narrowing of the racial disparity gap over time. Black children consistently incurred higher hospital costs (median difference: $629 [95% confidence interval: $500–$758; P < .01). The total inflation-adjusted hospital costs for Black children were $518 658 984, and $59 372 044 (11.41%) represented the excess because of the racial disparities in perforation rates.

CONCLUSIONS

Although all patients had a progressive decline in post appendectomy complications, Black children consistently had higher rates of complications and perforation, imposing a significant economic burden. We provide an empirical economic argument for sustained efforts to reduce racial disparities in pediatric surgical outcomes, notwithstanding that eliminating these disparities is simply the right thing to do.
Secularismo, religião e o problema da emancipação humana em Marx
Authors: Oliveira Juliano Cordeiro da Costa , De Carvalho Mayra Carneiro
Published: September 2021

O artigo objetiva investigar a relação entre secularismo e religião na sociedade burguesa à luz do problema da emancipação humana, a partir de escritos do jovem Marx, como, por exemplo, Sobre a Questão Judaica, Crítica da Filosofia do Direito de Hegel – Introdução, entre outros, que dizem respeito ao momento inicial de seu pensamento crítico; além de A Ideologia Alemã, obra posterior em que Marx retoma algumas das discussões iniciadas naquele período. A novidade trazida por Marx para o debate tradicional entre secularismo versus religião é que tudo isso só pode ser pensado a partir da emancipação humana, e não apenas da emancipação política. A sobrevivência da religião na modernidade não significa um desvio da secularização na história moderna, uma traição à Filosofia das Luzes ou mesmo um antagonismo em relação à emancipação política. Ao contrário, ela é consequência de uma secularização que não enfrentou as contradições de uma sociedade capitalista. Por um lado, Marx considerava a religião o “ópio do povo”, e que toda crítica teria como modelo a crítica à religião. Por outro, entretanto, a religião não deixava de ser, ao mesmo tempo, um grito de revolta contra uma sociedade excludente e a miséria de um mundo. A hipótese, portanto, a ser investigada neste artigo é que a análise da religião, em Marx, não se reduz meramente a um anticlericalismo de sua época, uma vez que tem como horizonte a emancipação humana, e não apenas política. Não se trata, em Marx, de um simples combate entre as luzes e as trevas no plano das consciências, e, sim, acima de tudo, de uma crítica às contradições da sociedade burguesa. Marx não possui de forma sistematizada uma teoria crítica da religião. Deste modo, sistematizaremos determinadas discussões que Marx apresentou ao longo de seus escritos, objetivando investigar a problemática proposta neste artigo.
Desenvolvimento moral na educação infantil
Authors: Barrios Alia , Branco Angela Uchoa
Published: September 2021

O presente estudo fundamentou-se, teórica e metodologicamente, na perspectiva da psicologia cultural construtivista. Teve como objetivo identificar e analisar a qualidade afetiva, mensagens culturais e os processos e estratégias presentes nas interações professora-crianças, possivelmente significativos para o desenvolvimento moral dos alunos. Participaram da pesquisa uma professora e 16 alunos do terceiro período de uma instituição pública de educação infantil situada em Brasíli, Distrito Federal. A análise microgenética das interações sociais professora-crianças e a análise interpretativa do discurso da professora fizeram parte da metodologia qualitativa utilizada. O estudo aponta para a importância da aprendizagem e da reflexão do educador sobre questões morais, bem como da sua atenção às interações que estabelecem com as crianças. Também, salienta a necessidade de criar espaços que possibilitem a avaliação construtiva do fazer pedagógico e de formação do educador, em relação ao desenvolvimento e educação moral de seus alunos, sendo necessários novos trabalhos de pesquisa sobre o tema, no sentido de contribuir ainda mais nessa direção.
Autonomia e responsabilidade
Authors: Lopes Juliana Crespo , Magalhães Suzana Maria do Nascimento , Moura Ana Luísa Lopes Lima , Pulino Lucia Helena Cavasin Zabotto
Published: September 2021

A partir das reflexões de duas formandas de Pedagogia acerca de uma experiência de prática pedagógica vivenciada em uma disciplina no primeiro semestre do curso, discute-se acerca da construção da autonomia e da responsabilidade no meio acadêmico. Entendendo que se fazia necessário despertar em estudantes o interesse pelo aprendizado, a docente pautou-se em Carl Rogers para elaborar a disciplina de modo a promover um ambiente onde estudantes fossem conscientes e ativos no processo de construção de conhecimentos. Especificamente no tocante à formação de professores, entende-se que é ainda mais vital que exista e se amplie esse tipo de experiência ao longo da graduação, tanto com vistas a uma formação de mais envolvimento e qualidade quanto no fomento de novas práticas pedagógicas na educação básica por meio da atuação de estudantes que se tornam docentes.
Andragogia
Authors: Soek Ana Maria , Haracemiv Sonia Maria Chaves
Published: September 2021

Compreender o processo de desenvolvimento pessoal e de aprendizagens ao longo da vida, pela ótica de como o aprendiz adulto aprende e se desenvolve, é objetivo primordial deste trabalho. Outra questão é situar aspectos do desenvolvimento pessoal, problematizando a sua importância para compreender a pessoalidade, individualidade face ao coletivo e aspectos sociais e de identidades. Nesse âmbito, destaca-se a análise em pelo menos três óticas relacionadas à educação de adultos na atualidade: lógica humanista, no sentido de desenvolvimento integral da pessoa humana; lógica laboral, do homem como sujeito construtor de si mesmo e transformador da realidade pela ação do trabalho; lógica do bem estar social, abordagem da psicologia positiva e a concomitante construção pessoal e de participação social, em que os adultos colaboram no desenvolvimento de uma sociedade melhor para todas as idades. Sublinha-se, igualmente, a necessidade de novos olhares, a fim de contribuir para os fundamentos de um futuro paradigma de educação de adultos.
Variations and some clinically relevant relations of A. cystica in pigs - a corrosion cast study
Authors: Stefanov I. S. , Tsandev N. S. , Vodenicharov A. P.
Published: September 2021

The aim of this study was to investigate the variations as well as the length of A. cystica and its branches in pigs using corrosion casting method with the self-polymerising resin Duracryl® Plus. The method included several steps: hepatectomy, precasting treatment, injection of Duracryl, polymerisation of casting medium, corrosive treatment, cleaning of the corrosion casts, air-drying and preservation of casts. The livers were collected from 12 male 6-month-old pigs (crossbred Landrace×Danube White). With regards to the beginning of A. cystica, 4 variations were observed and grouped as follows: variation A  A. cystica detached from R. dexter medialis, together with R. quadratus (variation A1), or alone (variation A2); variation B1 – A. cystica originated from A. gastroduodenalis, or was a branch of the common trunk (R. dexter) (variation B2). The metric data were processed by GraphPad Prism 6 for Windows. Clinically relevant relations between А. сystica, Ductus cysticus, A. celiaca and R. sinister also were described. The new information re-ceived about the blood supply of the gallbladder would contribute to the understanding of the etiology of postoperative complications as a result of surgical interventions in this location and for their prevention.
The Role of Social Networks as a Tool for an Effective Recruitment Process in the Enterprises in Kosovo
Authors: Dragusha Blerim , Prenaj Vlora
Published: September 2021

This paper focuses on the determinants of the impact of social networks on the recruitment process in Kosovar enterprises, concluding that the main factor of that impact is the quality of information, cost benefits, and timeliness. Another factor of particular importance is the competitive advantages social networks provide with respect to efficiently attracting suitable candidates to recruit through their unified data processing speed. The managers interviewed in this study provided evidence that recruitment using social networks is faster than with traditional methods. Social networks enable firms to quickly and easily access applicants from all over the world easily at a low cost. Social networks provide in-depth discussions to understand the views and opinions of both parties in the recruitment process. The information provided by social networks on the personal and professional life of the potential job candidate makes social networks an important tool for recruitment
Development of Corporate Social Responsibility in Business as a Factor of Fiscal Decentralization
Authors: Baranova Valeriia , Kulinich Tetiana , Dutchak Olena , Zvonar Viktor , Denyshchenko Liudmyla
Published: September 2021

The study aimed to substantiate the nature of the influence and sustainability of corporate social responsibility (CSR) on the effectiveness of the fiscal decentralization of local government in Ukraine. The estimates of CSR indicators for 490 enterprises were obtained using the questionnaire results. Determined the structure of directions for implementing a socially-oriented approach in Ukrainian business. Functions of dependence of indicators of the effectiveness of financial decentralization of local authorities on CSR development were constructed using linear regression methods and considering the time lag. We have identified a stimulating but not sustainable impact of business CSR on increasing the financial base of local budgets in decentralization. The time lag hurts the growth of the company's tax payments due to the growth of CSR level. The results obtained can be used to form efficiency strategies of local government to initiate CSR development in businesses.
An Approach to Assessing the National Multidimensional Poverty Line in Russia
Authors: Kormishkina Ludmila , Kormishkin Evgenii , Ermakova Eka , Koloskov Dmitrii
Published: September 2021

This study aims to econometrically assess multidimensional poverty in Russia with regard to the quantitative and qualitative parameters of the population’s life-sustaining activities. Russia’s partial integrated poverty indices were constructed based on a combination of quantitative and qualitative parameters characterizing the possibilities of satisfying needs in the main spheres/sectors of human values. The indicators that affect the poverty level in the country were determined using linear regression models. The available time lag in the regression models enabled us to make a short-term forecast of changes in the poverty level in Russia. The proposed approach to assessing the national poverty level considers monetary indicators related to the level of income of the population, the affordability of services necessary to meet human needs, and the presence of opportunity costs, which imply sacrificing a person's free time to ensure the material wellbeing necessary for life
Perturbation-based balance assessment: Examining reactive balance control in older adults with mild cognitive impairments
Authors: Kannan Lakshmi N , Bhatt Tanvi S
Published: September 2021

Background

Older adults with mild cognitive impairment (OAwMCI) present subtle balance and gait deficits along with subjective memory decline. Although these presentations might not affect activities of daily living (ADLs), they attribute to a two-folded increase in falls. While changes occurring in volitional balance control during ADLs have been extensively examined among OAwMCI, reactive balance control, required to recover from external perturbations, has received little attention. Therefore, this study examined reactive balance control in OAwMCI compared to their healthy counterparts.

Methods

Fifteen older adults with mild cognitive impairment (OAwMCI), fifteen cognitively intact older adults (CIOA) (>55 years), and fifteen young adults (18–30 years) were exposed to stance perturbations at three different intensities. Behavioral outcomes postural COM state stability, step length, step initiation, and step execution were computed.

Results

Postural COM state stability was the lowest in OAwMCI compared to CIOA and young adults, and it deteriorated at higher perturbation intensities (P < 0.001). Step length was the lowest among OAwMCI and was significantly different from young adults (P < 0.001) but not from CIOA. Unlike OAwMCI, CIOA and young adults increased their step length at higher perturbation intensities (P < 0.001). OAwMCI showed longer recovery step initiation times and shorter execution times compared to CIOA and young adults at higher perturbation intensities (P < 0.001).

Conclusion

OAwMCI exhibit exacerbated reactive instability and are unable to modulate their responses as the threat to balance control altered. Thus, they are at a significantly higher risk of falls than their healthy counterparts.
The influence of external load variables on creatine kinase change during preseason training period
Authors: Csala Dániel , Kovács Bence Márk , Bali Péter , Reha Gábor , Pánics Gergely
Published: September 2021

Objective

The aim of the present study was to analyse the relationships between creatine kinase (CK) concentration, an indirect marker of muscle damage, and global positioning system (GPS)-derived metrics of a continuous two-week-long preseason training period in elite football.

Design

Twenty-one elite male professional soccer players were assessed during a 14-day preseason preparatory period. CK concentrations were determined each morning, and a GPS system was used to quantify the external load. A generalized estimating equation (GEE) model was established to determine the extent to which the external load parameter explained post-training CK levels.

Results

The GEE model found that higher numbers of decelerations (χ
2 = 7.83, P = 0.005) were most strongly associated with the post-training CK level. Decelerations and accelerations accounted for 62% and 11% of the post-training CK level, respectively, and considerable interindividual variability existed in the data.

Conclusion

The use of GPS to predict muscle damage could be of use to coaches and practitioners in prescribing recovery practices. Based on GPS data, more individualized strategies could be devised and could potentially result in better subsequent performance.
Distribution modeling of Psellogrammus kennedyi (Eigenmann, 1903) and new records in the Lower Paranapanema River, Brazil
Authors: Jarduli Lucas Ribeiro , Pereira Alan Deivid , Garcia Diego Azevedo Zoccal , Ferraz João Daniel , Geller Iago Vinicios , Orsi Mario Luís
Published: September 2021

Understanding the potential distribution of non-native species can be an important tool in preventing biological invasions. We recorded for the first time Psellogrammus kennedyi, a small non-native characiform, in the Lower Paranapanema River, Brazil. According to environmental variables and prediction modeling, the species presents high potential distribution in the Upper Paraná river basin. The model used herein is an efficient tool to determine where non-native species may be able to establish. This approach can be used as a preventive measure, once the control and eradication measures are often ineffective and uneconomical.
Machine Learning for Medical Coding in Health Care Surveys
Authors: Lucas Christine , Hadley Emily , Nance Jason , Baumgartner Peter , Thissen Rita , Plotner David , Carr Christine , Tatum Aerian
Published: September 2021

This exploratory study evaluates the use of machine learning classifiers to perform automated medical coding for large statistical healthcare surveys.
National Hospital Care Survey Demonstration Projects: Severe Maternal Morbidity in Inpatient and Emergency Departments
Authors: Alford Josephine , Williams Sonja , Oriaku Michelle , White Donielle , Schwartzman Alexander , Jackson Geoffrey
Published: September 2021

This report demonstrates the ability of the National Hospital Care Survey (NHCS) to examine delivery hospitalizations involving severe maternal morbidity (SMM).
Endothelial cell monolayer formation on a small-diameter vascular graft surface under pulsatile flow conditions
Authors: Khanova M. Yu. , Velikanova E. A. , Matveeva V. G. , Krivkina E. O. , Glushkova T. V. , Sevostianova V. V. , Kutikhin A. G. , Antonova L. V.
Published: September 2021

Objective: to create a cell-populated small-diameter vascular graft (SDVG) using autologous endothelial cells and extracellular matrix proteins, and to evaluate the efficiency of endothelial cell monolayer formation during shear stress preconditioning in a SDVG.

Materials and methods. PHBV/PCL tubular scaffolds of vascular grafts were made by electrospinning from a mixture of polyhydroxybutyrate-valerate (PHBV) copolymer and polycaprolactone (PCL) and modified with fibrin. To populate the graft, an endothelial cell culture was isolated from the blood of patients with coronary heart disease. Phenotyping of endothelial colony-forming cell (ECFC) culture was performed by flow cytometry and immunofluorescence microscopy. Cell proliferative and angiogenic activity were also studied. Cell-populated vascular scaffolds were cultured in a pulsatile flow setup with a final shear stress of 2.85 dyne/cm2. The effect of pulsatile flow on monolayer formation was assessed by immunofluorescence, scanning electron microscopy, atomic force microscopy, and whole-transcriptome RNA sequencing.

Results. Under the influence of pulsatile flow, endothelial cells that were seeded into the tubular scaffold showed an increase in the expression level of endothelial profile proteins, focal adhesion and cytoskeleton. In contrast to endothelial cell culture on a vascular graft surface under static conditions, when cultured under pulsatile flow with 2.85 dyne/ cm2 shear stress, endothelial lining cells have an increased ability to adhere and are oriented along the pulsatile flow path. Whole-transcriptome RNA sequencing showed that induced shear stress increased expression levels of differentially expressed genes encoding proteins that ensure vascular development, endothelial integrity, and endothelial metabolism. A protocol for fabrication of a personalized cell-populated biodegradable SDVG under pulsatile flow conditions was developed.

Conclusion. The use of autologous fibrin and ECFC culture, as well as shear stress preconditioning, allow to obtain a personalized cell-populated SDVG with continuous functional endothelial monolayer adapted to the flow.
Immunosenescence as a reason of individualizing immunosuppressive therapy in kidney transplantation
Authors: Fedulkina V. A. , Vatazin A. V. , Kildyushevskiy A. V. , Zulkarnayev A. B. , Gubina D. V. , Fedulkina M. P.
Published: September 2021

Transplantation in elderly patients is obviously more challenging due to existing underlying diseases, changes in pharmacokinetics of immunosuppressive drugs, polypragmasy, and transformation of immunoreactivity (immunosenescence). Our review presents data on modification of adaptive and innate immunity during aging. It also considers the possibility of both reduced and adapted immunosuppressive therapy in elderly renal transplant recipients in achieving an optimal balance between efficacy and complications.
Organ donation and transplantation in the Russian Federation in 2020 13th Report from the Registry of the Russian Transplant Society
Authors: Gautier S. V. , Khomyakov S. M.
Published: September 2021

Objective: to monitor the current trends and developments in organ donation and transplantation in the Russian Federation based on the 2020 data.

Materials and methods. Heads of organ transplant centers were surveyed through questionnaires. Data control was done using the information accounting system of the Russian Ministry of Health. Between separate federal subjects of the Russian Federation and between transplantation centers, comparative analysis of data obtained over years was performed.

Results. Based on data retrieved from the 2020 Registry, 44 kidney, 29 liver and 16 heart transplantation programs were functioning in the Russian Federation in 2020. The kidney transplant waitlist in 2020 included about 11.5% of the total 60,000 patients receiving dialysis. Organ donation activity in 2020 was 3.9 per million population, with a 74.6% multi-organ procurement rate and an average of 2.9 organs being procured from one effective donor. In 2020, there were 7.7 kidney transplants per million population, 3.8 liver transplants per million population and 1.7 heart transplants per million population. Same year, the number of transplant surgeries performed in the Russian Federation fell by 19.2% to 13.4 per million population against the background of the outbreak caused by the new coronavirus disease COVID-19. The city of Moscow and the Moscow region in 2020 accounted for 13 out of the 14 functioning organ transplantation centers, performing 66.3% of all kidney transplants and 72.4% of all extrarenal transplants in the country. The number of organ recipients in the Russian Federation have exceeded 130 per million population.

Conclusion. In 2020, despite the new coronavirus disease COVID-19 pandemic and accompanying restrictive measures, transplant centers continued to perform organ transplants, run a waiting list and monitor organ recipients. However, the number of effective donors (–22.9%) and organ transplants (–19.2%) decreased, tentatively to the 2017 levels. In 2021, transplant centers with support from health authorities will have to restore the volume of transplant care with consideration to the real needs of the population and the donor resource. The COVID-19 factor, including vaccination of the population, as well as financial support to transplantation programs, will be decisive in shaping the trend of transplantation care and organ donation in the federal subjects of the Russian Federation in the coming 1–2 years.
The evaluation of postural stability and fall risk in morbidly obese preoperative bariatric patients: A cross-sectional study
Authors: YILMAZ Nurdan , BULBULOGLU Ertan
Published: September 2021

Amaç: Obez bireylerin, obez olmayan bireylere göre daha fazla postural instabilite ve düşme riskinde artış gösterdiği bilinmektedir. Morbid obez preoperatif bariatrik hastalarda postural stabiliteyi, düşme riskini ve postural stabiliteye katkıda bulunan faktörleri değerlendirmeyi amaçladık.

Gereç ve Yöntemler: Çalışmamıza bariatrik cerrahi öncesi değerlendirilen morbid obez 38 hasta (vücut kitle indeksi (VKI)≥40) ve 52 obez olmayan (BMI
Diferentes temperaturas de água de irrigação na cultura do feijoeiro
Authors: Pereira Cassiano Spaziani , Oliveira Douglas , Fiorini Ivan Vilela Andrade , Silva Adriano Alves da
Published: September 2021

Dentre os períodos de semeadura do feijão, o considerado “inverno” ou “irrigado” é aquele semeado no período sem chuvas de maio a setembro, necessitando exclusivamente de irrigação. A forma mais comum de irrigação do feijão de “inverno” ocorre por meio de pivôs centrais de irrigação, nestes sistemas a água caminha longas distâncias advindas de corpos d´água chegando as plantas com as mais distintas características físicas, químicas e de temperatura. Diante disso, o objetivo do trabalho foi verificar a influência de diferentes temperaturas da água de irrigação, sobre o feijoeiro comum cultivar Dama. O experimento foi conduzido na casa de vegetação do Viveiro Florestal da Universidade Federal do Mato Grosso (UFMT), campus Sinop e utilizou-se como tratamento a irrigação de plantas de feijoeiro em vasos de 8 L, distribuídos em quatro blocos ao acaso no período entre os meses de junho e julho. Aplicaram-se as seguintes temperaturas: 10°C, 15°C, 20°C, 25°C, 30°C, 35°C e 40°C. A irrigação com as diferentes temperaturas foi realizada desde a semeadura, até o início do florescimento, estádio R1. Foi avaliado o crescimento vegetativo das plantas (altura; número de folhas; área foliar e massa seca da parte aérea), a massa seca radicular e os teores de clorofila Clorofilog®. A variação de temperatura da água de irrigação de 10°C até 40°C não alteraram as variáveis altura de plantas, diâmetro de caule, número de folhas e massa seca de parte aérea. A água aplicada com temperatura de 30°C fez as plantas atingirem maior peso de raiz, já o tratamento de 35°C apresentou melhores resultados para índice de clorofiloG®.
RİSKTEN KORUNMA YAKLAŞIMI ÇERÇEVESİNDE ULUSLARARASI HİSSE SENEDİ YATIRIMLARI İLE TİCARET ARASINDAKİ İLİŞKİ
Authors: ATICI USTALAR Sinem
Published: September 2021

Çalışmanın amacı ülkeler arasındaki ikili mal ticaretinin ikili hisse senedi yatırımları üzerindeki riskten korunma etkisini analiz etmektir. Analiz, finansal çekim modeli ile 2001-2018 yılları için gerçekleştirilmiştir. Modelde 65 ülkenin ikili hisse senedi yatırımları, ikili ihracat ve geleneksel çekim değişkenleri kullanılmıştır. Model ilk aşamada En Küçük Kareler (EKK) ve Poisson-Pseudo En Çok Olabilirlik (PPML) tahmincileri ile tahminlenmiştir. İkinci aşamada ise ihracat ve ikili hisse senedi yatırımları arasındaki içsellik probleminin kontrolü için Araç değişkenler yöntemi ile İki Aşamalı EKK (2AEKK) tahmincisi kullanılmıştır. Model sonuçlarına göre, kaynak ve destinasyon ülke arasındaki artan ihracat, yabancı yatırımcı için hisse senedinin riskini azaltmakta ve ikili hisse senedi yatırımını artırmaktadır. Dolayısıyla, ülkeler arasındaki ihracat ikili hisse senedi yatırımı üzerinde riskten korunma etkisine sahiptir.
CHOP TMC Single Cell Multiome ATAC + Gene Expression v1
Authors: Hu Po , Pei Liming
Published: September 2021

The human heart is vital for our survival and health, and it presents remarkable anatomical, cellular and functional heterogeneity. The four chambers of the heart, together with specialized arteries, veins, valves and conduction cells, perform distinct yet essential physiological functions. A significant gap of knowledge is that different cell's molecular signature, spatial distribution and interactions, and functional state remain little understood at the single-cell level. The goal of the heart Organ-Specific Project (OSP) is to address this knowledge gap and generate high quality, single-cell resolution, longitudinal imaging and multiomics data of normal human hearts across the entire human lifespan. To achieve this goal, we propose the following three specific aims: 1) To refine protocols of biospecimen processing, multiomics and imaging assays and define inter-individual variability using our existing banked normal human hearts. 2) To procure, archive and annotate high-quality normal heart samples across the entire human life span. We have established a streamlined procurement and biorepository infrastructure to support our heart OSP. We will procure normal heart and bone from the same donor of 5 different age groups across the entire human life span. 3) To spatially and quantitatively profile normal heart specimens across the entire human lifespan using a set of robust and scalable imaging and single-cell omics assays. In summary, the heart OSP will broadly impact the entire research community and jumpstart basic-science and medical discoveries based on a sophisticated understanding of the key molecular circuits underlying the development and aging of human heart.
Quantification of nonprotein sulfhydryl groups (NPSH) optimized for zebrafish brain tissue v2
Authors: Sachett Adrieli , Gallas-Lopes Matheus , M M Conterato Greicy , Benvenutti Radharani , P Herrmann Ana , Piato Angelo
Published: September 2021

Zebrafish are incresingly used as a model animal in neuroscience research. Here we describe a protocol to quantify nonprotein sulfhydryl groups (NPSH), an indirect evaluation of the levels of reduced glutathione (GSH), a major oxidative stress defense in the central nervous system.
iBlot2--CHEM 584 v1
Authors: Christensen Ken
Published: September 2021

Transferring your proteins from your SDS-PAGE gel to a nitrocellulose membrane for western blot is quick and straightforward.
Continuous renal replacement therapy for critically ill patients in the intensive care units of two tertiary hospitals. v1
Authors: Machado Alba Jorge
Published: September 2021

Introduction: Acute kidney injury is characterized by a sudden decrease in renal function. The objective was to determine the variables that are associated with the need for continuous renal replacement therapy and its outcome in critically ill patients treated in two intensive care units. Methods. A cohort follow-up study with reviewed clinical histories of 140 patients admitted between January-2012 and July-2015, who were receiving continuous therapy, and the main outcome was survival after discharge. Clinical variables, severity scores, disease prognosis, continuous renal replacement techniques and outcomes were collected. Results. Mean age was 61.9±17.6 years, and 60.7% were men. Septic shock was the main cause of acute kidney injury. In total, 79.4% of cases died in the intensive care units. The median dose of continuous renal replacement therapy was 28 ml/kg/hour (interquartile range: 35-37). The late initiation of the therapy between 25-72 hours after the diagnosis increased the probability that the patient would experience a fatal outcome (OR:6.9, 95%CI:1.5-33.0). Conclusions: Acute kidney injury secondary to sepsis is a frequent condition in critically ill patients and is associated with high mortality rates. In these cases, continuous renal replacement therapy was the main recourse for its treatment.
Integrating Life Skills through Physical Activities Programs
Authors: Anira A , Syarifatunnisa S , Ma'mun Amung , Rahayu Nur Indri
Published: September 2021

The purpose of this study was to investigate the integration of life skills through physical activities programs on the improvement of student life skills. The population of this study was 64 college students in Indonesia divided into two groups (experimental group n = 34 and control group n = 30). The sampling technique used cluster random sampling. The research method used was a quasi-experiment with a pre-test post-test control group design. The instrument used was the life skills scale for sport adaptation (LSSS) which consists of eight components, namely teamwork, goal setting, time management, emotional skills, communication, social skills, leadership, problem-solving, and decision making. The results showed that the physical activity integrated with the life skill program had a more significant impact on the improvement of the student's life skills than the physical activity without the integration of the life skill program. Further findings revealed that the social skill component was the life skill component that gained the highest increase. It shows that the integration of life skill programs in physical activities provides better results than physical activities without the integration of life skills programs.
Sex Differences in Blood Pressure and Body Composition in Hypertensive Adults with Central Obesity
Authors: Adriyani Riza , Iskandar Dody , Dana Ahmad Hendra
Published: September 2021

Regular exercise is recommended for adults experiencing hypertension with low and moderate cardiovascular risk. High intensity interval training (HIIT) is an efficient training method and has a better cardiometabolic protective effect. The purpose of this study was to determine sex differences in blood pressure and body composition after high intensity interval training. Twenty two adults with hypertension and central obesity (male n = 16, age 35.56 ± 4.56 years, waist circumference 98.85 ± 6.85 cm, systolic blood pressure 134.22 ± 2.86 mmHg, diastolic blood pressure 85.03 ± 6.58 mmHg) - (female n = 6, age 37.83 ± 5.46 years, waist circumference 95.09 ± 7.49 cm, systolic blood pressure 133.50 ± 6.47 mmHg, diastolic blood pressure 89.80 ± 5.94 mmHg) participated in a high intensity interval training (HIIT). The HIIT consisted of 3x4 minutes training at 77– 95% of maximum heart rate interspersed by 3 minutes of active rest at 64-76% of of maximum heart rate. The training was conducted three sessions per week for 10 weeks. Systolic blood pressure and diastolic blood pressure were significantly reduced in men. There was an improvement in body composition parameters, including a decrease in waist-to-hip ratio, visceral fat, and body fat mass in men (p 0.05). Waist circumference decreased in both men and women (p 0.05). It concludes that there are sex differences in cardiometabolic adaptation after HIIT.