bluuebunny/crossref_metadata_2025 huggingface dataset:
ATIVIDADES FARMACOLÓGICAS DAS FOLHAS DA SESBANIA VIRGATA (CAV.) PERS
Authors: Braggio M.M. , Lima M.E.L. , Veasey E.A. , Haraguchi M.
Published: September 2024

RESUMO As atividades farmacológicas do sumo liofilizado (SL) das folhas da Sesbania virgata (Sv) (Cav.) Pers. foram estudadas in vivo. A administração oral do SL de 0,5 a 2 g/kg em ratos e camundongos produziu ptose, reduziu a motilidade espontânea e dispnéia. A DL50 foi de 11,30 (10,04 ↔12,71) g/ kg, indicando ausência de toxicidade. O tratamento oral com SL (1 e 2 g/kg) em camundongos não alterou a latência mas aumentou a duração do sono induzido pelo pentobarbital sódico (50 mg/ kg, i.p.). A atividade antinociceptiva do SL foi avaliada pelas contorções abdominais induzidas por ácido acético e pelo teste da formalina; enquanto que atividade antiinflamatória foi verificada pela indução do edema por óleo de cróton em orelhas e por carragenina nas patas de camundongos, respectivamente. O SL (1 e 2 g/kg) causou diminuição dose-resposta das contorções abdominais, inibiu em 91 e 89 %, a 2a fase da resposta no teste da formalina, reduziu o edema induzido por óleo de cróton em 58 e 61% e diminuiu em 24 e 31% o edema da pata induzido por carragenina, respectivamente. Os resultados demonstraram que o tratamento oral em camundongos com S. virgata diminui a reação ao estímulo doloroso e reduz o edema inflamatório.
BRUCELOSE CANINA - RELATO DE CASO
Authors: Megid J. , Ribeiro M.G. , Moraes C.C.G. , Nardi Júnior G. , Paes A.C. , Prestes N.C. , Listoni F.J.P.
Published: September 2024

RESUMO Relata-se a ocorrência de brucelose em um cão sem raça definida, com três anos de idade. Ao exame clínico o animal apresentava aumento de volume testicular esquerdo, sem histórico de lesão traumática no local. A citologia aspirativa por agulha fina do testículo afetado permitiu o isolamento de Brucella canis. Procedeu-se a terapia utilizando rifampicina e estreptomicina, simultaneamente à indicação de orquiectomia bilateral do animal. Exames histopatológicos revelaram infiltrado neutrofílico e necrose de coagulação no testículo direito e reação granulomatosa com infiltrado mononuclear no testículo esquerdo. Cultivo microbiológico de sangue, urina e líquido prostático resultaram negativos para o isolamento do agente. As provas de soroaglutinação rápida em cartão e imunodifusão em gel de ágar resultaram positivas no animal relatado, bem como em duas fêmeas contactantes, com histórico de abortamento recente.
CUTANEOUS PYTHIOSIS IN A SLAUGHTERED HORSE: A CASE REPORT
Authors: Headley S.A. , Arruda Jr H.N. , Leggi T.C.S.S. , Bett V.
Published: September 2024

ABSTRACT Cutaneous pythiosis in a horse submitted for slaughter is described in Northern Paraná, Brazil. The animal presented an ulcerative, granulomatous lesion on the lateral surface of the left forelimb just above the elbow joint. Histopathological evaluation revealed an eosinophilic granulomatous reaction associated with intralesional hyphae characteristic of Pythium insidiosum visualized by Gomori’s methenamine silver stain. Other cutaneous equine lesions easily confused with cutaneous pythiosis are discussed and differentiated. Suggestion for gross identification of these lesions and the final destination of horsemeat infected by P. insidiosum during Federal Inspection are given.
A CARAPUÇA DA DISCÓRDIA: UMA ANÁLISE DOS DISCURSOS QUE EMANAM DE UM GESTO PRESIDENCIAL
Authors: Araldi Inês Staub
Published: September 2024

Resumo No dia 2 de julho de 2003, o Presidente da República Luís Inácio Lula da Silva recebeu em audiência os líderes do Movimento dos Trabalhadores Rurais Sem Terra e, em clima de camaradagem, posou para fotografia com um boné do MST na cabeça. Tal acontecimento produziu discursos cujos sentidos não estão nas palavras empregadas, mas nas condições de produção que as originaram, as quais são analisadas neste artigo através dos recursos da Análise do Discurso.
DEFINING A CALL ACTIVITY
Authors: Leffa Vilson J.
Published: September 2024

Abstract The objective of this paper is to explain CALL (Computer-Assisted Language Learning) through Activity Theory (AT). First, a summary of AT is presented, based on the ideas of Leontiev and Engström. It is shown how the subject appropriates the object through the mediation of a tool and the relationship with the other members of the community in which he or she is inserted. The basic principles which guide AT are also described, emphasizing its hierarchical levels. Secondly, an attempt is made to demonstrate how AT can be applied to a CALL activity. The conclusion is that AT, considering that it includes both synchronic and diachronic aspects of the problem under investigation, has the capability of integrating the different perspectives and explain many of the conflicts of an essentially interdisciplinary and theoretically fragmented area, as is the case of CALL.
TEMPO NA FRASE E TEMPO NO TEXTO: AS TEORIAS DE REICHENBACH E DE ROJO E VEIGA
Authors: Freitag Raquel Meister Ko.
Published: September 2024

Resumo Este artigo apresenta um estudo comparativo das teorias de Reichenbach (1947) e de Rojo e Veiga (1999) para a estruturação lingüística das relações temporais no âmbito da frase e do discurso. Em um primeiro momento, compara as teorias no que se refere à orientação, representação e arranjo. Em seguida, analisa as propostas de estruturação temporal estabelecidas para além dos limites da frase, ou seja, como as teorias estruturam o tempo no texto.
A CAUSALIDADE: ANÁLISE DE ENUNCIADOS PRODUZIDOS EM UMA REUNIÃO DE IMOBILIÁRIA
Authors: Dottori Filho Almiro , Ikeda Sumiko Nishitani
Published: September 2024

Resumo O objetivo deste trabalho é examinar a causalidade, as formas de sua expressão, os diferentes significados de ‘porque’ e suas funções discursivas, em turnos conversacionais de uma reunião de uma imobiliária. A pesquisa apontou para os seguintes resultados: (a) muitas orações introduzidas por ‘conjunção subordinativa’ não são realmente subordinadas; por outro lado, a relação causa-efeito nem sempre é sinalizada por meios tradicionais e, além disso, podendo ocorrer implicitamente, caso em que o ouvinte precisa deduzir a conexão através do contexto; (b) existem três tipos de causalidade: de conteúdo, epistêmica e de ato de fala; e (c) a construção causal envolve outras funções discursivas: dentro da perspectiva dialógica da linguagem, ela emerge em geral depois de relações retóricas de contraste e negação ou, mais genericamente, depois de proposições que vão contra as expectativas partilhadas. Baseamo-nos especialmente em Jordan (1998), Sweetser (1990) e Ford (1994; 2000), que estudaram as essas questões no inglês, para compará-las na língua portuguesa.
FIGURATIVE POSITIONING IN MEDIAWORTHY RADIO TALK
Authors: Kupferberg Irit
Published: September 2024

Abstract A current longitudinal research project explores how meaning is constructed discursively in troubled talk between sufferers and professionals in various help sites (e.g., internet forums, the radio and the hotline). Espousing discourse-oriented functionalist approaches (i.e, institutional conversation analysis, linguistic anthropology and narrative inquiry), the researchers show that troubled selves often construct their problems through stories as well as certain story-internal key figurative forms summarizing the main point of the problem. This project also shows that such narrative and figurative versions of the suffering self often enhance interpersonal communication. Espousing a discourse-oriented functionalist approach, and the Four World Model, the present study further explores troubled radio talk showing that in this public arena the effectiveness of organizing figurative language is often constrained by the ability of troubled selves to present media-worthy stories.
A PSYCHOLINGUISTICS ANALYSIS OF THE METAPHOR “DIFFICULTIES ARE WEIGHTS”*
Authors: Macedo Ana Cristina Pelosi Silva de
Published: September 2024

Abstract Partial findings of an on-going research concerned with obtaining a deeper understanding of the mental scenes construed for the DIFFICULTIES ARE BURDENS metaphor are presented. In order to do so, two experiments were run with forty participants, students of the University of California, at Santa Cruz, U. S. A. and Universidade Federal do Ceara, Brazil, involving a word-choice task and a description task, respectively. Both experiments were aimed at obtaining a better knowledge of people´s intuitions as regards their perceptions of weight. Analyses results suggest that, contrary to primary metaphor hypothesis, socio-cultural factors do play a role in the composition of scenes people have internalized for the metaphor´s source domain.
A COMPREENSÃO DE METÁFORAS POR PORTADORES DE LESÃO NO HEMISFÉRIO DIREITO: UMA INVESTIGAÇÃO A SER (RE)CONSIDERADA
Authors: Fachini Sônia Regina Victorino
Published: September 2024

Resumo Observações clínicas de pacientes com hemisfério direito lesionado mostram que, apesar de apresentarem preservadas suas habilidades lingüísticas, eles possuem preferências em assinalar as interpretações literais, rejeitando as implicações metafóricas. Este artigo apresenta o resultado de um estudo empírico realizado com sujeitos destros normais e sujeitos destros portadores de lesão no hemisfério direito, em específico na artéria média cerebral, em três tarefas de compreensão de metáforas. Os dados colhidos revelaram algumas tendências divergentes da literatura, pois não foram encontradas diferenças significativas entre as duas populações testadas.
Phyto- and Zooplankton of the Khadzhybey Estuary (2016, 2021-2023)
Authors: Dyadichko V. G. , Kharitonova Yu. V. , Garkusha O. P.
Published: September 2024

Seasonal and interannual changes in the taxonomic structure, numbers and biomass of phytoplankton and zooplankton, and also in zooplankton production were investigated in the Khadzhybey estuary in 2016 and 2021-2023. Totally 36 species of phytoplankton of five divisions and 24 taxa of zooplankton were
found. The highest biomass of phyto- and zooplankton were observed in the middle and upper sections of the estuary. In terms of the quantitative indices of phytoplankton development, the Khadzhybey estuary is a highly eutrophic water body characterized by the constant water bloom formed by Cyanoprokaryota. All registered zooplankton organisms belong to fish food objects. The average annual values of zooplankton biomass differed several times, but the taxonomic
composition and predominance of individual species in the community remained unchanged. At the present time, zooplankton biomass is higher than that observed prior to 2016. Despite the fact that the maximum numbers and biomass of zooplankton were registered in 2021, the highest zooplankton production was
observed in 2022.
Peculiarities of the Toxic Effect of Synthetic Surfactants on Hydrophytes (a Review)
Authors: Gorbatiuk L. O. , Pasichna O. O.
Published: September 2024

Scientific data of recent years on some aspects of the impact of synthetic surfactants on algae and higher aquatic plants are summarized in the review. In particular, information on the sensitivity of hydrophytes to the action of synthetic surfactants and the nature and mechanisms of their toxic effect on hydrophytes and their interspecies interaction was analyzed. The possibility of using hydrophytes for the biodegradation of synthetic surfactants in aquatic ecosystems is also discussed.
Hydrological and Morphological Characteristics of the Water Bodies of the Irpin River Basin in View of Hostilities' Impact
Authors: Ivanova N. O. , Dubniak S. S. , Zorina-Sakharova K. Ye. , Lietytska O. M. , Nezbrytska I. M. , Pohorielova M. S. , Prychepa M. V. , Afanasyev S. O.
Published: September 2024

Based on analysis of the archive, literature and cartographic data and results of the field surveys in 2023-2024, distribution of the water bodies (WB in terms of EC WFD) was established. The ratio was established between the linear and
polygonalWBincluding natural and candidates to the heavily modified. The WB distribution was assessed according to the significant changes of the certain descriptors. They included catchment area, length, water surface area and depths (for polygonal WB), as well as WB distribution owing to the main modifying factor (regularity degree and morphological modifications), and assessment of the risk of not-achieving the ecological objectives. The peculiarities of the water regime of the studied rivers within individual WB, the flow-influencing factors, decrease in the minimum flow rate, and changes in morphological features were analyzed. The crucial role of the Irpin drainage system in the anthropogenic transformation of the rivers of the basin and specific conditions in the estuary of the Irpin River supported by the Kyiv Reservoir were considered. The main hydrological and morphological effects of hostilities in the basin (flooding of the Irpin River estuary, destruction of hydraulic constructions and bridges) were assessed. It is proposed to partially adjust the boundaries of the delineated WBs and delineate additional WB due to changes in the basin under the hostilities impact.
On stress ratio equations in three-dimensional stress space for modelling soil behaviour
Authors: Handspiker Wyatt , Liu Zhenyu , Ghafghazi Mason
Published: September 2024

Constitutive models and failure criteria of soils, rocks, and other materials often need to be extended beyond the triaxial state where they are usually defined, for plane strain, axisymmetric, or three-dimensional analyses. This extension is commonly done by making the stress ratio a function of the Lode angle. This process turns two-dimensional yield, plastic potential, bounding, dilatancy and similar surfaces into three-dimensional shapes such as cones and bullets. The equations used have a range of shapes on the octahedral or π-plane between Mohr-Coulomb’s irregular hexagon and Drucker-Prager’s circle. Nine stress ratio generalization equations popular in soil mechanics are evaluated based on numerical stability, agreement with available data, and ease of implementation. The computed limits on their convexity, and the flexibility they offer in the calibration process are discussed. At the end, a new equation that satisfies all these criteria while remaining simple and easy to calibrate is proposed, implemented in a finite element model, and demonstrated to improve numerical stability and efficiency.
Mechanical properties of steel fibre–UHPC interface: Experimental study and numerical simulation
Authors: Bin Huang , Feixiang Xue , Mingzi Gong , Wei Huang , Axin Pan , Yu Yang
Published: September 2024

The aim of this study was to investigate the interfacial mechanical attributes between steel fibre (SF) and an ultra-high-performance concrete (UHPC) matrix. Using both experimental testing and numerical simulation, a comprehensive analysis on the pull-out process of SF from the UHPC matrix was conducted. The effects of fibre embedment depth, fibre diameter and fibre embedment angle on the mechanical properties of the SF–UHPC interface were examined. In the fibre pull-out tests, the maximum pull-out force of the group of specimens with different embedment depths showed a trend of rapid rise and then slow development, and the pull-out work increased with an increase in embedment depth. The maximum pull-out force and pull-out work of the group with variable fibre diameters increased with an increase in fibre diameter. The maximum pull-out force and pull-out work of the group with different embedment angles increased first and then decreased with an increase in embedment angle. The maximum pull-out force was 72.5 N when the embedment angle was 45° and the maximum pull-out work was 214.4 N.mm when the embedment angle was 30°. The results of finite-element simulations were found to be in good agreement with the experimental results.
Cardiac Localized Polycystin-2 in the Natriuretic Peptide Signaling Pathway and Hypertension
Authors: Márquez-Nogueras Karla M. , Elliott Brandon , Thuo Paula , DiNello Elisabeth , Knutila Ryne M. , Fritzmann Geena E. , Vuchkovska Virdjinija , Flury Sarah , Willis Monte , Chapman Arlene B. , Cao Quan , Barefield David Y. , Kuo Ivana Y.
Published: September 2024

Key Points

Cardiac localized polycystin facilitates natriuretic peptide signaling pathways.

Hypertension associated with autosomal dominant polycystic kidney disease may arise from impaired cardiac natriuretic peptide signaling.

Background

Hypertension is seen in 70% of patients with autosomal dominant polycystic kidney disease by age of 30 years before decline in kidney function. However, cardiac origins of hypertension, such as the natriuretic peptide signaling pathway, have not been fully investigated. We hypothesized that cardiomyocyte localized polycystin proteins contribute to production of natriuretic peptides, and loss of this pathway would contribute to hypertension.

Methods

Telemetry, echocardiography, and a molecular analysis of the natriuretic peptide pathway from left ventricular tissue of cardiomyocyte specific knockout models of polycystin-2 (cPC2-KO) mice and Cre control littermates were conducted. Complementary studies were conducted in ex vivo murine hearts, engineered heart tissue with human iPSCs driven into cardiomyocytes with CRISPR/Cas9 knockout of PKD2 and in in vitro cell lines.

Results

cPC2-KO mice demonstrated diurnal hypertension. Circulating atrial natriuretic peptide (ANP) and brain natriuretic peptide were unchanged between cPC2-KO and Cre mice. Analysis of the pathways involved in production, maturation, and activity of natriuretic peptides identified decreased transcription of chromogranin B, PCSK6, NPR1, and NFAT genes in cPC2-KOs. Human iPSC-derived cardiomyocytes with PC2-KO failed to produce ANP. Re-expression of polycystin-2 in a myoblast cell line, but not pathogenic forms of polycystin-2, restored ANP production.

Conclusions

Natriuretic peptide production required cardiac localized polycystin-2, and loss of this pathway may contribute to the development of hypertension in autosomal dominant polycystic kidney disease.

Podcast

This article contains a podcast at https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/JASN/2024_10_08_ASN0000000000000490.mp3
Production of Acetylcholine by Podocytes and its Protection from Kidney Injury in GN
Authors: Truong Luan D. , Trostel Jessica , Roncal Carlos , Cara-Fuentes Gabriel , Miyazaki Makoto , Miyazaki-Anzai Shinobu , Andres-Hernando Ana , Sasai Fumihiko , Lanaspa Miguel , Johnson Richard J. , Garcia Gabriela E.
Published: September 2024

Key Points

Our study demonstrated the sole enzyme responsible for acetylcholine production, choline acetyltransferase, was expressed in podocytes.

Acetylcholine decreased glomerular injury in GN by reducing inflammation and protecting endothelium.

Choline acetyltransferase/acetylcholine production was induced in podocytes with drugs already available.

Background

One of the most important factors modulating endothelial health is acetylcholine; and while it is associated as a cholinergic neurotransmitter, it is also expressed by non-neuronal cells. However, its role in the kidney, which does not receive cholinergic innervation, remains unknown.

Methods

To determine whether acetylcholine is produced in the kidney, we used choline acetyltransferase (ChAT) (BAC)–enhanced green fluorescent protein (ChAT mice) transgenic mice in which enhanced green fluorescent protein is expressed under the control of the endogenous ChAT transcriptional regulatory elements. We then investigated the role of acetylcholine in kidney disease by inducing antiglomerular basement membrane GN (anti-GBM GN) in ChAT transgenic mice.

Results

We demonstrate ChAT, the sole enzyme responsible for acetylcholine production, was expressed in glomerular podocytes and produced acetylcholine. We also show during anti-GBM GN in ChAT transgenic mice, ChAT expression was induced in the glomeruli, mainly in podocytes, and protects mice from kidney injury with marked reduction of glomerular proliferation/fibrinoid necrosis (by 71%), crescent formation (by 98%), and tubular injury (by 78%). By contrast, specific knockout of podocyte ChAT worsened the severity of the disease. The mechanism of protection included reduction of inflammation, attenuation of angiogenic factors reduction, and increase of endothelial nitric oxide synthase expression. In vitro and in vivo studies demonstrated available drugs such as cholinesterase inhibitors and ChAT inducers increased the expression of podocyte-ChAT and acetylcholine production.

Conclusions

These findings suggest de novo synthesis of acetylcholine by podocytes protected against inflammation and glomerular endothelium damage in anti-GBM GN.

Podcast

This article contains a podcast at https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/JASN/2024_12_05_ASN0000000000000492.mp3
Retrospective Evaluation of Pediatric Patients Hospitalized with Brucellosis: Single Center Study in Istanbul
Authors: Karaaslan Ayşe , Çetin Ceren , Akçay Merve , Beytorun Damla , Haykır Zehir Nahide , Çağ Yakup , Akın Yasemin
Published: September 2024

Aim: Brucellosis is a zoonotic disease and mainly develops as a result of consuming products of infected animals such as cattle, sheep and pigs.

Material-Methods: Pediatric patients under the age of 18 who were hospitalized with a diagnosis of brucellosis in a third-level city hospital were included in the study. Serology titer ≥1:160 and/or Brucella spp in blood culture growth was determined as the diagnostic criterion for the diagnosis of brucellosis.

Results: Of the 35 pediatric patients diagnosed with brucellosis, 22 were boys and 13 were girls, and the average age was determined as 154.2 ± 53.1 months (25-214). Hospital admission complaints were determined in order of frequency as follows; joint pain (51.4%), fever (31.4%), headache (17.1%) and abdominal pain (5.2%). Eleven of the patients (31.4%) had polyarthralgia and 7 (20%) had monoarthralgia. The most common physical examination findings were hepatomegaly (48.6%) and splenomegaly (40%), respectively. Joint involvement was detected in 17.1% of the patients. Sacroiliac joint involvement was reported in 3 (8.6%) patients, ankle joint involvement in 2 (5.7%) patients, and knee joint involvement in 1 (2.9%) patient. Anemia (60%) was the most common hematological finding. The average hemoglobin value was determined as 12.5±1.44 (10.2-15.9) g/dl. When patients are compared in terms of joint involvement; neutrophil count and treatment duration were found to be statistically higher in patients with joint involvement (p<0.05).

Conclusion: Brucellosis is a zoonotic disease that is endemic in our country, affects all age groups, and can cause complications and relapses, and continues to be a serious public health problem for our country.
Validation of High-Resolution Continuum Source Flame Atomic Absorption Spectrometry for Determination of Selected Toxic Metals in the Decontamination Process of Wastewater Discharged in Natural Receivers
Authors: Senna Bame Sanah , Masamba Wellington , Obuseng Veronica , Frentiu Tiberiu , Angyus Bogdan Simion , Covaci Eniko
Published: September 2024

A new method based on high-resolution continuum source flame atomic absorption spectrometry (HR-CS FAAS) was validated for the determination of selected toxic metals in wastewater resulting from mining activity, compared to inductively coupled plasma optical emission spectrometry (ICP-OES) and line-source flame atomic absorption spectrometry (LS FAAS). The HR-CS FAAS method was characterized by detection limits (LODs) in the range (μg L–1) 1(Mn)–30(Pb), better than ICP-OES for Cu, Fe, Ni, Co, Pb and Mn, and poorer for Cd, Zn and Cr. Dunnett’s test showed that both methods were not affected by significant bias against certified values. The recovery in the HR-CS FAAS method was in the range of 98–103% with relative extended uncertainty of 9–18% and precision of 2–11%. Compared to LS FAAS, the HR-CS FAAS presented better LODs for Pb and Cr. The HR-CS FAAS method is suitable for determining selected toxic elements in filtered water samples without any chemical treatment.
Preparation of Porous Imidazole-based Poly(ionic liquid) Adsorbents and Their Toluene Adsorption Performance
Authors: Luo Fangwen , Tian Xujiao , Dong Xian , Liang Longchao , Chen Zhuo
Published: September 2024

Efficient, economical, and durable adsorbents are required to remove volatile organic compounds (VOCs) from air. Cross-linked polyvinylic ionic liquids (PVIC) with porous structures were synthesized by quaternizing 1-vinylimidazole (1VI) with 1-bromobutane to obtain 3-butyl-1-vinylimidazolium bromide (VIC), which was then co-polymerized with divinylbenzene (DVB) radicals. 1H NMR, 13C NMR, scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy, and N2 adsorption–desorption isotherms were applied in characterizing the composites. Through modification of the polymer structure by adjustment of DVB concentration（the ratio of DVB concentration to VIC concentration was x: 1 (x = 0.4, 0.6, 0.8, 1.0) and the product was named PVIC-x (x = 2, 3, 4, 5)), the optimal PVIC-4 pore structure was obtained, with a specific surface area and total pore volume of 192.5 m2 g–1 and 0.192 cm3 g–1, respectively. A toluene adsorption test verified the adsorption capacity. The adsorption behavior for VOCs, based on toluene, was investigated using adsorption breakthrough curves, adsorption kinetics, and isotherms. The adsorption process is well describing by the Bangham kinetic and Langmuir isotherm models. The dynamic adsorption of toluene was in the order of PVIC-4 > PVIC-5 > PVIC-3 > PVIC-2. The optimal toluene adsorption capacity of PVIC-4 was 264.4 mg g-1 with an equilibrium time of 56 minutes, which was attributed to its excellent pore structure. PVIC-4 also performed well in terms of recycling rate, maintaining 91.19% adsorption efficiency after 5 cycles of recycling. PVIC-4 has the potential to remove volatile organic compounds from the air.
Extraction System for the Spectrophotometric Determination of Tungsten(VI) with 4-Nitrocatechol and Benzalkonium Chloride
Authors: Divarova Vidka V. , Stojnova Kirila T. , Radkovska Ivelina D. , Saravanska Antoaneta D. , Toncheva Galya K. , Delchev Vassil B. , Gavazov Kiril B.
Published: September 2024

A novel chromogenic system for the liquid-liquid extraction and determination of trace amounts of tungsten(VI) was investigated. The system comprises 4-nitrocatechol (4NC) as a chromogenic reagent, sulfuric acid as a complexing medium, and benzalkonium chloride (BAC) as a source of bulky cations (BA+), which readily form chloroform-extractable ion-association complexes. The impact of foreign ions and reagents was studied, and the optimal conditions for the sensitive, selective, and inexpensive determination of tungsten(VI) were identified. The limit of detection, linear working range, and molar absorptivity at λmax (422 nm) were determined to be 31 ng cm−3, 0.1–4.4 μg cm−3, and 5.49 × 104 dm3 mol−1 cm−1, respectively. The composition of the extracted complex was 1:2:2 (W:4NC:BA). Two potential structures of its anionic component, [WO2(4NC)2]2–, were discussed based on optimizations at the B3LYP/CEP-4G theoretical level and comparison between theoretical and experimental spectra.
α-Synuclein Protein Preparation (Large scale) with Sedimentation and Thioflavin T Assays v1
Authors: X. Henderon Michael
Published: September 2024

This is a collection of protocols consisting α-synuclein protein preparation (large scale), thioflavin T Assay, and sedimentation assay.
Thermodynamik in Druckbehältern zur Druckstoßsicherung
Authors: Haakh Frieder
Published: September 2024

Die richtige Auslegung von Druckbehältern zur Druckstoßsicherung erfordert die zutreffende Beschreibung der thermodynamischen Vorgänge, insbesondere des Wärmeaustauschs mit dem Druckluftpolster. Der Beitrag stellt hierzu einen Berechnungsansatz vor, der die wesentlichen Bilanzgrößen des Wärmeübergangs erfasst. Diese sind der konduktive und der konvektive Wärmeübergang, die Kondensationswärme des Wasserdampfes bei der Dekompression, die Strahlungswärme der Wand, die durch auskondensierte Nebeltröpfchen aufgenommen wird sowie die Erstarrungswärme bei Unterschreiten des Gefrierpunktes. Validiert wird der Ansatz durch Messwerte durch Abgleich der Veränderung der inneren Energie des Druckluftpolsters. Die Daten aus Dekompressions-, Kompressionsversuchen sowie von Pumpenabschaltungen zeigen eine gute Übereinstimmung. Damit kann der meist verwendete, aber ungenaue Ansatz mittels konstantem Polytropenexponenten in Druckstoßprogrammen ersetzt werden.
Evaluación del Índice Neutrófilos-Linfocitos en lesionados severamente quemados
Authors: Zaldívar Castillo Dayamí , Palacios Alfonso Irene
Published: September 2024

Introducción: Las quemaduras son lesiones devastantes que se asocian a alta morbilidad y mortalidad. Se produce desbalance inmunológico, afectando los leucocitos, primera línea de defensa ante cualquier noxa, fundamentalmente los neutrófilos y linfocitos. Con el objetivo de evaluar el Índice Neutrófilos-Linfocitos en los lesionados severamente quemados, se realiza éste estudio. Método: . Estudio descriptivo, longitudinal y prospectivo, en el servicio de Caumatología del Hospital Universitario Calixto García, desde enero 2022 a diciembre 2022.Se incluyó a todos los ingresados clasificados como Grandes Quemados, con menos de 24 horas de evolución de la lesión, entre 19 a 60 años. Se excluyó a pacientes con enfermedades crónicas no transmisibles descompensadas. Se tomaron muestras de sangre venosa a las 72 horas y al 6to día post trauma, para determinar valores de Índice Neutrófilos Linfocitos. Se relacionaron dichos valores con el estado al egreso y con el Pronóstico de Vida. De un total de 134 ingresados, 36 cumplieron los criterios de inclusión. Resultados: . Predominaron los lesionados masculinos, el fuego directo el principal agente causal, y los accidentes prevalecieron sobre otros mecanismos de producción. El Índice Neutrófilos Linfocitos se elevó desde las primeras 72 horas de evolución, con valores mayores en los lesionados con peor pronóstico de vida, y en los egresados fallecidos. Conclusión: . Existió una asociación lineal entre los valores de Índice Neutrófilos/Linfocitos en lesionados egresados vivos y los que fallecieron, así como relación directamente proporcional con la gravedad de la lesión.
Aspectos jurídicos de los factores psicosociales en el lugar de trabajo: Un derecho laboral fundamental
Authors: Sibaja Terán Beatriz
Published: September 2024

Se presenta una reflexión sobre los puntos relevantes de la aplicación del marco legal para vigilar y controlar los factores psicosociales en el lugar de trabajo. De forma rápida se realiza un comparativo de las condiciones laborales y los efectos que son reconocidos en la legislación de cinco países, posteriormente, se identifican los síntomas reconocidos desde una perspectiva ocupacional. Se concluye que futuros estudios deben contemplar la evolución del impacto de la evaluación psicosocial y sus consecuencias en la regulación de los cuidados de la salud y bienestar de los trabajadores.
Migrante Económico: Revisión Conceptual y Criterios para su Tratamiento Jurídico
Authors: Matheus Hidalgo Mayerlin
Published: September 2024

El concepto “migrante económico” no tiene desarrollo normativo, lo que deriva en confusiones con otras categorías migratorias e impide que se le aplique un derecho idóneo.
En este trabajo se analiza el derecho internacional aplicable al migrante económico, se diferencia a este migrante de otras categorías migratorias y se exponen las razones de por qué sería errado considerar a una misma persona en más de una categoría migratoria y, finalmente, se realizan precisiones en torno al concepto estudiado estableciendo que, como parte del estándar mínimo para el tratamiento de este migrante, se debería reconocer su personalidad jurídica como presupuesto necesario para el desarrollo de su proyecto de vida.
Impacto de los programas de transferencias monetarias sobre la pobreza multidimensional en Colombia, 2013-2020
Authors: Sotelo-Forero Lorena , Vallejo-Zamudio Luis E.
Published: September 2024

Cash transfer programs have been implemented as a strategy to reduce poverty and improve the well-being of the most vulnerable families. This paper uses the Quality of Life Survey and the Propensity Score Matching technique to analyze the impact of the Colombia Mayor and Familias en Acción programs on the Multidimensional Poverty Index (MPI) in Colombia. The results show that participating in these programs significantly impacts the reduction of the MPI. However, the analysis also reveals deficiencies in the complementarity between the beneficiaries of the programs and the people identified as poor, which indicates errors of inclusion and exclusion of a part of the most vulnerable population in the cash transfer programs. This demonstrates the need to improve the targeting mechanism to effectively reduce multidimensional poverty.
Analysis of the relationship between the cognitive functions affected by work stress and the psychosocial risk factors of workers in companies in the tourism sector in Colombia: Sincelejo case
Authors: Hoyos-Babilonia Lorena , Santamaría Álvaro , Niebles-Nuñez William
Published: September 2024

One of the biggest issues organizations face today is how work stress affects employees’ cognitive abilities. In the Colombian context, these issues coexist with the stress factors that are present. Workers are constantly at risk for psychosocial risks. For this reason, the current study aims to describe the influence of work stress on the cognitive functions of employees of hotel companies in the city of Sincelejo, Sucre, and from this, determine whether there is a significant correlation between said variable and the psychosocial risk factors. On a methodological level, a descriptive field study was developed in which a survey on a Likert scale was applied to a sample of 53 managers of companies in the hotel sector, correlating the presence of work stress in cognitive functions such as Annual evaluation and future project, Concentration and attention, Memory, Errors, Immediate reactions, and Logic and organization. The impairment of each of the cognitive functions examined and the psychosocial risk factors described in the present study were then found to be significantly correlated, both generally and specifically, using the Kendall correlation coefficient, which was evaluated indicator by indicator. This conclusion was reached as a result of the analysis. By addressing and minimizing the psychosocial risk factors identified in this study, it was determined that it is important to promote healthier work environments and enhance employees’ cognitive resilience.
Incidencia de la realidad aumentada en el desarrollo de competencias lectoras
Authors: Roberto-García Laura Ximena , Mesa-Jiménez Fredy Yesid , Rodríguez-Hernández Ariel Adolfo
Published: September 2024

A review of intervention works focused on the use of Augmented Reality (AR) in reading and reading comprehension processes is presented, from which the following categories emerged: 1) Promotion of reading through interactive books with AR, 2) AR and reading comprehension, 3) AR in reading comprehension of English and Spanish as a foreign language and 4) AR and reading for inclusive education. A qualitative methodology was used with the documentary review method with the following stages: 1) delimitation and search in scientific databases, 2) review, selection and classification of research papers since 2008, 3) initial outline, 4) writing of contents, 5) a draft and 6) final report. Reading with AR was evidenced as a new mixed reading format that affects, due to the fact that the exchange with additional virtual information, presented in virtual environments, makes the reading process more motivating, attractive, interesting, playful and immersive with follow-up and immediate feedback, compared to traditional methods. It is also attributed to a change in the role of the teacher and incidence in memorization, concentration, problem solving, participation and self-learning at the pace of each student, aspects that influence reading comprehension. Reading with the support of mobile devices can distract the reader, as there are more tasks involved in the process, so this type of reading will advance from being a less instrumental process for the user.
Tendencias y modelos emergentes en autoevaluación para la acreditación de programas de doctorado en educación en américa latina
Authors: Montes-Miranda Alexander Javier , Alarcón-Lora Andrés , Munera-Cavadia Liris
Published: September 2024

This research, titled “Trends and Emerging Models in Self-Assessment for Accreditation of Doctoral Programs in Education in Latin America,” aimed to analyze innovative trends in self-assessment procedures applied to doctoral programs in education. Through document analysis, recent accreditation frameworks and regional self-assessment models were reviewed. The results indicated a shift towards qualitative indicators measuring social impact and innovation, and a harmonization of accreditation criteria with international standards. An increasing incorporation of technologies in self-assessment was observed, although challenges persist in equitable access to these technologies. The study concludes that self-assessment of the quality of these programs is being constructed from the perspective of university social responsibility, reflecting a shift in doctoral programs, focusing on both academic production and social contribution. The inclusion of a broader range of stakeholders in these processes provides a more holistic view of the effectiveness of academic offerings.
The Foreign Language Course Design in the Context of Electronic Informational-Educational Environment Implementation
Authors: Крылова О.В.
Published: September 2024

Рассматриваются теоретические основы проектирования учебных курсов в многоплановой информационно-образовательной среде. Показаны особенности моделирования процесса обучения иностранным языкам, этапы внедрения электронной информационно-образовательной среды, преимущества и ограничения электронных ресурсов. Описано преобразующее влияние искусственного интеллекта на модернизацию образовательного контента на примере учебной дисциплины «Иностранный язык».

The theoretical foundations of designing training courses in a multifaceted information and educational environment are considered. The features of modeling the process of teaching foreign languages, the stages of introducing an electronic information and educational environment, the advantages and limitations of electronic resources are shown. The transformative influence of artificial intelligence on the modernization of educational content is described using the example of the academic discipline “Foreign Language”.
Exploring the Possibilities of Using Artificial Intelligence in music Teaching
Authors: Дубровский В.В. , Горбик Я.А.
Published: September 2024

Цель данной статьи – представление результатов изучения возможностей применения искусственного интеллекта в обучении музыке. Анализируются исследования, посвященные проблематике использования искусственного интеллекта в обучении музыке. Осуществляется диссеминация актуального педагогического опыта применения нейросетей в образовательной деятельности. Определяются ключевые направления развития методики обучения музыке с использованием искусственного интеллекта. Ключевой метод исследования – интервьюирование. Сделан вывод о том, что большинству музыкальных педагогов доступны только коммерческие нейросети; использование искусственного интеллекта в образовательном процессе преследует периферийные цели (повышение мотивации учения, развитие художественной культуры, функциональной грамотности). Развитие музыкальных навыков с использованием нейросетей в настоящий момент реализуется в двух направлениях: обучение нотной грамоте и оценка музыкальных навыков.

The purpose of this article is to present the results of studying the possibilities of using artificial intelligence in music teaching. Research on the use of artificial intelligence in music teaching is analyzed. The dissemination of current pedagogical experience in the use of neural networks in educational activities is carried out. The key directions for the development of music teaching methods using artificial intelligence are determined. The key research method is interviewing. It is concluded that most music teachers only have access to commercial neural networks; the use of artificial intelligence in the educational process pursues peripheral goals (increasing motivation to learn, developing artistic culture, functional literacy). The development of musical skills using neural networks is currently being implemented in two directions: teaching musical notation and assessing musical skills.
Distinctive Features of Vocal Education Systems in China and Russia
Authors: Теряева О.А. , Шалаева А.А.
Published: September 2024

Рассмотрены актуальные проблемы профессиональной подготовки будущих педагогов по вокалу в системах высшего образования России и Китая. Определены объективные параметры для проведения сравнительно-сопоставительного анализа образовательных программ, реализуемых в китайском и российском вузах. Описаны черты сходства и различия в организации образования, позволяющие эффективно проектировать образовательный процесс в двух странах. На основе опыта преподавания, авторских исследований, изучения научной литературы обоснованы выводы по совершенствованию профессиональной подготовки обучающихся из Китая в российских и китайских музыкально-педагогических вузах.

The current problems of professional training of future vocal teachers in the higher education systems of Russia and China are considered. Objective parameters have been determined for conducting a comparative analysis of educational programs implemented in Chinese and Russian universities. The similarities and differences in the organization of education are described, which make it possible to effectively design the educational process in two countries. Based on teaching experience, original research, and study of scientific literature, conclusions on improving the professional training of students from China in Russian and Chinese music pedagogical universities are substantiated.
Potencjał jednostek samorządu terytorialnego w gospodarce postcovidowej
Authors: Filipiak Beata Zofia , Wyszkowska Dorota , Dylewski Marek , Sierak Jacek
Published: September 2024

The potential of local government units in the post-covid economy
There is a discussion in the literature on the subject of the multidimensional impact of various factors on the financial situation of local government units (LGUs). Taking into account the fact that the financial situation of local government units significantly affects their development opportunities, implies the quality of tasks performed, and is also a factor stimulating the quality of life of residents, there is a need to discuss various aspects of the potential of local government units.
The aim of this study is to organize existing views on socio-economic problems, pandemic and environmental challenges that have significantly influenced changes in the potential of local government units. Moreover, the authors’ aim is to provide methodological support in the approach to measuring potential, especially financial and investment potential. Therefore, theoretical issues are illustrated based on practical examples.
The first chapter included a discussion and systematization of views on the concept of potential, its evolution, and a position on terminological boundaries and its components. The second chapter discussed methods of approaching the measurement of the potential of local government units in its various aspects. The third chapter was devoted to the operating surplus, which is permanently treated in local government units as an important parameter used in the assessment of the ability to absorb debt in formal terms, but also as an element of the assessment of financial potential as the ability to generate free funds. The fourth chapter demonstrates the role of EU revenues in financing current and investment tasks and indicates the directions of allocation of these funds.
A new area covered in the monograph is the definition of a new risk area that influences the development of the potential of local government units, which is ESG risk. The monograph is of a methodological and discussion nature, organizing the considerations, but also presenting the practical use of the proposed methodology for measuring various types of potential, taking into account ESG risk.
La responsabilidad civil médico-sanitaria: Principales desafíos en torno a la lex artis durante la pandemia por Covid-19 en el Perú
Authors: Barco Hidalgo Gino Leonardo Miguel
Published: September 2024

Uno de los temas de discusión claves durante y después de la pandemia ocasionada por la aparición del covid-19 alrededor del mundo, es la responsabilidad civil generada a propósito de la actuación de los profesionales de la salud (tomando en cuenta la estructura sanitaria) ante las situaciones de emergencia imprevisibles en dicho contexto. De igual modo, el sistema de salud peruano se vio en la obligación de hacer frente a diversos desafíos, a través de herramientas como la aplicación de políticas públicas e implementación de normativa especial, que, en gran medida, tuvieron un impacto en la determinación de la responsabilidad de los profesionales de la salud durante el estado de emergencia sanitaria. En ese sentido, en el presente trabajo de investigación se abordará la responsabilidad civil médico-sanitaria, a partir de un estudio de la aplicación de la lex artis según el sistema jurídico nacional. Para ello, se partirá con un estudio de la responsabilidad civil médico-sanitaria en el Perú, detallando que tipos de obligaciones se aplican según el caso particular e identificando a los actores en el sistema sanitario que pueden ser imputados. En segundo término, se presenta a la lex artis como un parámetro de diligencia, para lo cual se brinda un estudio de conceptos y se le diferencia de nociones ligadas como la lex artis ad hoc. Finalmente, se establecen los principales desafíos que el Perú enfrentó durante la pandemia por covid-19 y su impacto en la determinación de la responsabilidad civil médico-sanitaria.
A Philosophical Interpretation of Nursing
Authors: Bishop Anne H. , Scudder John R.
Published: September 2024

The authors discuss their interpretation of nursing as the practice of caring. Through interpretive phenomenology, they lift out the essential meaning of nursing as practiced, and through generative interpretation of philosophical treatments of relationships, practice, and caring, they enlighten nursing practice. They discuss the implications of interpreting nursing as the practice of caring for nursing scholarship, education, and ethics.
Conversation Across Paradigms: Unitary-Transformative and Critical Feminist Perspectives
Authors: Cowling W. Richard , Chinn Peggy L.
Published: September 2024

The purpose of this article is to convey a conversation that occurred over a period of months between a unitary-transformative scholar and a critical feminist scholar. The intention of our conversation was to uncover, through dialogue and engagement, ways in which these two paradigms might help us understand the forces and conditions which impede and may liberate full expression of health and well-being. Areas of essential tensions addressed were the relationships of action and theory, sense and soul, stories and numbers, and aesthetics and empirics. Critical conversational points were notions of liberation, consciousness and social conditions, unpredictability and acausality, and potentials for reconciliation that would serve nursing and society. We concluded that although there are significant differences that exist between the two paradigms, there are areas in which we might begin to speak with one voice for the betterment of nursing and health care.