bluuebunny/crossref_metadata_2025 huggingface dataset:
Concepções de matemática que forjam o ensino médio programa nova EJA
Authors: Andrade Eliane Lopes Werneck de , Fantinato Maria Cecilia de Castello Branco
Published: September 2017

Este artigo apresenta parte dos resultados de uma dissertação de mestrado, defendida em 2016, na qual, buscou-se discutir como são vivenciados os processos de aprendizagem em matemática no Ensino Médio no Programa NOVA EJA. O contexto em que esses processos se dão é a politica pública, de aceleração e aprendizagem, denominada NOVA EJA, implementada no Rio de Janeiro desde 2013. Para isso, pesquisamos se e como a metodologia do programa promove a valorização de saberes matemáticos experienciais, advindos das práticas sociais dos alunos. O objetivo deste artigo é analisar as concepções de matemática que permeiam o material digital do programa. Estudos teóricos em Educação e Educação Matemática fundamentaram a pesquisa qualitativa, que ampliou, nosso olhar sobre os discursos contidos nos documentos oficiais e nas políticas educacionais, direcionadas às pessoas jovens e adultas.  Também foram realizadas observações em aulas de Matemática deste programa, em uma escola estadual, assim como entrevistas com cinco alunos. A análise dos dados permitiu deduzir que a concepção que perpassa o método de ensino oferecido, inclusive, no material disponibilizado aos docentes e discentes, pode levar os professores a pensar os alunos do programa de modo infantilizado e como sujeitos marginalizados das próprias práticas sociais.  Palavras-chave: EJA. Educação Matemática. Política educacional.
Percepções sobre os conhecimentos prévios em matemática nos anos iniciais e possíveis caminhos
Authors: Madruga Zulma Elizabete de Freitas , Gallon Mônica da Silva , Silva Carla Melo da
Published: September 2017

Esse artigo tem por objetivo analisar como um grupo de estudantes de Pedagogia na modalidade EaD de uma Universidade privada do Sul do Brasil compreende os conhecimentos prévios em Matemática nos anos iniciais, e possíveis estratégias para seu mapeamento. A investigação teve por base 83 respostas para um questionamento proposto em um fórum online, integrante de uma disciplina do referido curso. Os depoimentos foram voluntários, sem qualquer tipo de avaliação. Tratando-se de uma pesquisa qualitativa, dessas respostas foi realizada a Análise Textual Discursiva, resultando em duas categorias emergentes: valorização dos conhecimentos prévios e utilização de jogos e outros materiais concretos como facilitadores da aprendizagem. A investigação apontou a importância do diagnóstico para identificar os conhecimentos de Matemática pré-existentes nas crianças, a relevância do professor refletir sobre o que dados obtidos no diagnóstico inicial e sobre a sua prática de sala de aula, para que nesse processo de ação reflexão, contemple as necessidades de aprendizagem dos estudantes. Os resultados também sugerem a utilização de jogos e materiais concretos como facilitadores da aprendizagem e na construção do diagnóstico. Palavras-chave: Educação Matemática. Anos iniciais. Conhecimentos prévios.
O ensino da teoria da evolução em escolas da rede pública de Senhor do Bonfim: análise da percepção dos professores de ciências do ensino fundamental II
Authors: Oliveira Camila Laranjeira Costa de , Menezes Maria Cilene Freire de , Duarte Olívia Maria Pereira
Published: September 2017

Embora a Teoria da Evolução seja um tema de grande importância para a compreensão de assuntos relacionados às diversas áreas das ciências biológicas, é notória a dificuldade de compreensão do tema, principalmente no âmbito escolar. Dessa forma, o objetivo deste trabalho consiste em investigar a abordagem do ensino dessa teoria por professores de ciências dos anos finais (6º ao 9º ano) do ensino fundamental da rede pública do município de Senhor do Bonfim – Bahia. Também se buscou identificar as concepções dos professores sobre a temática e levantar os possíveis obstáculos ao ensino da Teoria da Evolução no ensino fundamental. A pesquisa caracteriza-se como qualitativa, utilizando-se como instrumentos de coleta de dados questionários compostos por perguntas fechadas e abertas. Os resultados demonstraram limitações no ensino da teoria evolutiva, relacionadas à formação inicial dos docentes; à existência de barreiras para o entendimento da teoria da evolução diante de concepções criacionistas e à falta de entendimento acerca do sistema de teorias evolutivas por parte dos docentes. Essas observações indicam que o ensino da Teoria da Evolução no ensino fundamental é deficiente e pode contribuir para a formação de concepções equivocadas acerca do tema. Palavras-chave: Ensino de Ciências. Concepções. Teoria da Evolução.
Interface metacognição e semiótica para a leitura de textos sincréticos
Authors: Rodrigues Ana Paula Teixeira de Amorin , Dos Santos Valdenildo
Published: September 2017

Por meio de pesquisa realizada junto a 59 alunos do 8º ano de duas escolas públicas de Três Lagoas, Mato Grosso do Sul, descobriu-se que o gênero textual preferido foram as Histórias em Quadrinhos. Portanto, foi selecionada uma HQ da turma da Mônica, cujo autor Maurício de Sousa faz uma crítica à economia do país e pedido que os alunos escrevessem uma primeira interpretação de forma livre sobre o que entenderam do texto. O material coletado serviu de base para a comprovação das hipóteses de que havia problemas de falta de motivação, leitura crítica e escrita de acordo com a norma padrão. Diante do quadro, foi elaborado um plano de ação com exercícios sobre metacognição (FLAVEL, 1979, SOLÉ, 1998), atividades inspiradas em sequência didática (DOLZ, NOVERRAZ & SCHNEUWLY, 2004), que contemplaram os níveis de leituras propostos pela semiótica francesa (GREIMAS E SEUS DISCÍPULOS), num processo de correção-interativa (RUIZ, 2015) e reescrita da escrita para a escrita (MARCUSCHI, 2010). São apresentados, portanto, aqui, a utilização da semiótica sincrética e sua importância como ferramenta para a abertura da percepção quanto ao sentido de enunciados que acoplam a linguagem verbal e não verbal, parte englobante de dissertação de mestrado defendida em 2016. Palavras-chave: Leitura Crítica, Semiótica Sincrética, Histórias em Quadrinhos.
La expresión temporal en Berceo
Authors: Lope Blanch Juan M.
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
El misterioso origen de Fernán González
Authors: Keller J. P.
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
Carlos Blanco Aguinaga, Unamuno, teórico del lenguaje. El Colegio de México, México, 1954; 130 pp.
Authors: Xirau Ramón
Published: September 2017

Se reseñó el libro: Unamuno, teórico del lenguaje.
Sobre un soneto de Gutierre de Cetina
Authors: Fucilla Joseph G.
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
Don Pedro de Cárdenas, mecenas y editor de Góngora
Authors: Serís Homero
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
Horacio Jorge Becco, "Don Segundo Sombra" y su vocabulario. Ediciones Ollantay, Buenos Aires, 1952; 161 pp.
Authors: Lope Blanch Juan M.
Published: September 2017

Se reseñó el libro: "Don Segundo Sombra" y su vocabulario.
María Rosa Lida de Malkiel, Juan de Mena, poeta del Prerrenacimiento español. El Colegio de México, 1950; 592 pp. (Publicaciones de la Nueva Revista de Filología Hispánica).
Authors: Lapesa Rafael
Published: September 2017

Se reseñó el libro: Juan de Mena, poeta del Prerrenacimiento español.
En torno a la etimología y evolución de "cansar", "canso", "cansa(n)cio"
Authors: Malkiel Yakov
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
Geochemical Characteristics of Metamorphic Rock-Hosted Gold Deposit At Onzon-Kanbani Area, Central Myanmar
Authors: Zar Aung Tay , Warmada I Wayan , Setijadji Lucas Donny , Watanabe Koichiro
Published: September 2017

Gold and associated base metal mineralization of Onzon-Kabani area located in the western border of generally N-S trending Mogoke Metamorphic Belt where well-known Sagaing fault is served as a western boundary of this area. In this research area, many artisanal and small-scale gold mines were noted in last three decades. Gold mineralization is hosted in marble and gneiss unit of research area but most common in marble unit. Variety of igneous intrusions are also observed in research area. Mineralizations are observed as fissure filling veins as well as lesser amount of disseminated nature in marble unit. Mineralogically, gold are associated with other base metal such as pyrite, galena, sphalerite, chalcopyrite, marcasite and arsenopyrite. Hydrothermal alteration halos are developed in peripheral of hydrothermal conduits or mineralization veins from proximal to distal such as 1) silicic, 2) sericite-illite, and 3) propylitic alteration.  Most of hydrothermal minerals from each altered zones showed that near neutral condition of pH (e.g. adularia, calcite, illite, sericite and chlorite). Alternatively, hydrothermal alteration zones that show with ore minerals such as native gold, electrum, sphalerite, galena, chalcopyrite, arsenopyrite and marcasite which mostly observed in silicic alteration zone. Typical boiling characters of vein textures and fluid inclusion petrography are observed in hydrothermal system of research area. Boiling, cooling and mixing are possiblily responsible for gold deposition in hydrothermal system. In this paper, authors are documented to clarify the type of mineralization based on hydrothermal alterations, ore and gangue mineral assemblages and fluid inclusion study. All of these data can describe and play an important role for both with respect to understanding deposit genesis and in mineral exploration.
Política ambiental y actividades militares
Authors: Arenas Cañón Alexander
Published: September 2017

Este artículo analiza el papel del sector militar, como parte de la estructura del Estado, en su relación con el medio ambiente. De igual manera, aborda el tema del impacto de variables ambientales en las actividades militares, tanto desde una perspectiva local como global, en la que los regímenes internacionales diseñados para la administración de los recursos naturales desempeñarían un papel primordial en el desarrollo de las políticas ambientales en el sector militar.
Sudán y la Corte Penal Internacional: el precio de las buenas intenciones
Authors: Molano Rojas Andrés
Published: September 2017

El artículo describe el proceso de intervención de la Corte Penal Internacional en Sudán en el marco de la crisis humanitaria de Darfur, y la forma en que llegó a ordenar la detención del presidente sudanés Ornar Al-Bashir; así como las posibles implicaciones de la decisión tanto para la credibilidad de la justicia internacional como para las perspectivas de paz en ese país.
La competencia de la Corte Penal Internacional en Colombia
Authors: Gardeazábal Rodríguez Juan Carlos
Published: September 2017

En marzo de 2009, la Corte Penal Internacional emitió, por primera vez, una orden de detención contra el presidente de Sudán, Omar Al-Bashir, señalado de ser responsable de crímenes de guerra y contra la humanidad en la región de Darfur, donde el conflicto ha dejado 300 mil muertos y 2,7 millones de desplazados. Con ello se demuestra que la comunidad internacional se ha dotado de mecanismos jurídicos y políticos para asegurar que este tipo de crímenes no queden en la impunidad.
Ciencia, Tecnología e Innovación, factor estratégico en las Fuerzas Armadas del futuro
Authors: Ariza Urango Ricardo
Published: September 2017

La investigación, el desarrollo tecnológico y la innovación han sido el eje que ha permitido la evolución de los pueblos a través de la historia. Muchos de estos avances se hicieron para suplir necesidades de los ejércitos (de tierra, mar y aire), que una vez implementados tuvieron una réplica en el campo civil, generándose una apropiación social de la tecnología. Como ejemplo se puede citar el proyecto ARPA del Pentágono, que consistía en tener una red informática que permitiera interconectar los computadores que comandaban los misiles estratégicos de Estados Unidos. Este proyecto se convirtió en lo que hoy se conoce como Internet, herramienta que no solo facilita la comunicación desde cualquier punto de la tierra, sino que está modificando las estructuras sociales de la humanidad.
Implicaciones geopolíticas del desarrollo de armas nucleares con fines político-militares por parte del Estado de Israel
Authors: Gardeazábal Rodríguez Juan Carlos
Published: September 2017

El desarrollo de armas nucleares es un tema muy sensible en la región del Medio Oriente, Israel ha mantenido bajo secreto los alcances de su programa nuclear y no es posible acceder a información clasificada. Se aclara que este artículo es parte de una investigación más amplia sobre el tema.

Actualmente, se estima que el Estado de Israel posee entre 200 y 500 armas nucleares que le dan la capacidad de responder a cualquier ataque. Esto le ha permitido ampliar su influencia en la región del Medio Oriente. También ha contribuido a una carrera armamentista por parte de los países vecinos que ejercen influencia en la región. En este contexto, los escenarios previsibles de guerra tienen alta probabilidad de ocurrir, y con ello amenazar la estabilidad del sistema internacional. Este documento propone desde el realismo, un análisis de los objetivos que motivan el desarrollo de un programa nuclear con relación al contexto político del Medio Oriente.
Armas no letales
Authors: Berrios Vogel Pablo Andrés
Published: September 2017

El artículo informa sobre las nuevas armas tecnológicas que se emplean en el campo de batalla, las cuales utilizan pulsos electromagnéticos para lograr sus objetivos, buscando una mayor protección de los seres vivientes y su entorno, afectando solamente sistemas electrónicos, lo que es aplicable a conflictos regulares como irregulares.
El factor científico–tecnológico en la defensa y seguridad nacional
Authors: Alas Sansur José Ernesto
Published: September 2017

Es necesario partir del hecho que “La ciencia es conocimiento y la tecnología es la aplicación de ese conocimiento para un uso determinado“; luego que no todas ellas están al alcance del hombre, ya sea porque de momento o se pueden obtener, no están a la venta, por restricciones comerciales o porque aventaja a quien la posea, entre otras razones. Sin embargo, la tecnología disponible en un país es la suma de la tecnología aprovechable a nivel mundial. Se plantea entonces que dependiendo de la capacidad de adquisición, generación, adaptación, acumulación y/o transferencia que un Estado tenga, se podrá decir de su desarrollo tecnológico. Lo anterior es suficiente para profundizar en las razones de la brecha tecnológica existente entre los países industrializados y los que están en desarrollo.
Tecnología biométrica con huellas digitales
Authors: Moreno Jiménez Pedro Pablo
Published: September 2017

La biometría es una forma de seguridad basada en el reconocimiento de una característica física e intransferible de la persona. Los sistemas biométricos incluyen un dispositivo de captación y un software que interpreta la muestra física y la transforma en una secuencia numérica.
Computadores e internet en la guerra interestatal: ¿La consolidación de un nuevo poder militar en el siglo XXI?
Authors: Gaitán Rodríguez Andrés
Published: September 2017

El presente documento hace parte de la investigación “El ciberespacio como campo de batalla en el siglo XXI”, la cual se adscribe a la Línea de Investigación en Desarrollo Científico, Tecnológico y Políticas Ambientales de la Escuela Superior de Guerra. El paulatino e histórico traslado de la guerra a nuevos teatros deconflagración como la tierra, el océano, el aire y espacio exterior como producto de los adelantos tecnológicos del hombre en materia militar, ha definido claramente el concepto polemológico del poder terrestre, marítimo, aéreo y espacial. Ahora, si los computadores se presentan como armamento para ser empleado en el ciberespacio (que se traduce como teatro de operaciones) por parte de los Estados (y sus Fuerzas Militares), será posible establecer la existencia de un poder ciberespacial en el presente.
3 solos (R. Murray Schafer) (CD Review)
Authors: Jurkowski Edward
Published: September 2017

[no abstract]
Srul Irving Glick (CD Review)
Authors: Sallis Friedemann
Published: September 2017

[no abstract]
Petite suite maritime (CD Review)
Authors: Stephen J. Drew
Published: September 2017

[no abstract]
Remain Calm! RDA, FRBR, and Music Libraries
Authors: Boyd Alastair
Published: September 2017

[no abstract]
Compositional Crossroads: Music, McGill, Montreal (Book Review)
Authors: Priest Eldritch
Published: September 2017

[no abstract]
Alcides lanza: Portrait of a Composer (Book Review)
Authors: Jurkowski Edward
Published: September 2017

[no abstract]
Alcides lanza (CD Review)
Authors: Jurkowski Edward
Published: September 2017

[no abstract]
Shakin’ all Over: Canadian Pop Music in the 1960s (DVD Review)
Authors: Van der Bliek Rob
Published: September 2017

[no abstract]
Canadian Organ Music Showcase (CD Review)
Authors: Buley David
Published: September 2017

[no abstract]
Five Cent Music: Publication of an Early Series of Canadian Sheet Music
Authors: Higham Peter
Published: September 2017

[no abstract]
Music, Libraries, and the Academy: Essays in Honor of Lenore Coral (Book Review)
Authors: Philpott Lisa
Published: September 2017

[no abstract]
Scherzo: Piano Music by Oskar Morawetz (CD Review)
Authors: Keillor Elaine
Published: September 2017

[no abstract]
Opportunity Knocks: Updating an Online Music Catalogue
Authors: Boyd Alastair
Published: September 2017

[no abstract]
Musical AKAs: Assumed Names and Sobriquets of Composers, Songwriters, Librettists, Lyricists, Hymnists, and Writers on Music (Book Review)
Authors: Guise Janneka L.
Published: September 2017

[no abstract]
A Midwinter Night’s Dream (CD Review)
Authors: Crutchley Ian
Published: September 2017

[no abstract]
The Ashgate Research Companion to Experimental Music (Book Review)
Authors: Stephen J. Drew
Published: September 2017

[no abstract]
Invisible Cities (CD Review)
Authors: Higham Peter
Published: September 2017

[no abstract]
Night Chill (CD Review)
Authors: Hung ERic
Published: September 2017

[no abstract]
Chura-Churum; The Merman of Orford (CD Review)
Authors: Leibel Jane
Published: September 2017

[no abstract]
Earth Songs (CD Review)
Authors: Power Brian E.
Published: September 2017

[no abstract]
Music and the Creative Spirit (Book Review)
Authors: Ross Gordon
Published: September 2017

[no abstract]
3 Concerti (CD Review)
Authors: Jurkowski Edward
Published: September 2017

[no abstract]
From the Heartland (CD Review)
Authors: Jurkowski Edward
Published: September 2017

[no abstract]
Sirocco - Sylvie Proulx (CD Review)
Authors: Higham Peter
Published: September 2017

[no abstract]
Still Rollin’ - Mike Murley Septet (CD Review)
Authors: McArthur Michael
Published: September 2017

[no abstract]
The effect of DAU and PAD to enconomic growth with capital expenditures as intervening variabels
Authors: Kusuma Manggar Wulan
Published: September 2017

This study aims to determine whether the general allocation funds and local revenue can affect economic growth in South Sulawesi Province by using variable capital expenditure as an intervening variable. The data source used is secondary data in the form of financial report of local government of regency / city in South Sulawesi Province in 2006 until 2013. Data analysis technique used is Partial Least Square (PLS) analysis. The result of the research shows that 1) General allocation fund has negative effect to capital expenditure; 2) Original revenue of the region has a positive effect on capital expenditure; 3) Capital expenditure negatively affects economic growth.
Release of 19 Waxy Winter Wheat Germplasm, with Observations on Their Grain Yield Stability
Authors: Graybosch R. A. , Baenziger P. S. , Bowden R. L. , Dowell F. , Dykes L. , Jin Y. , Marshall D. S. , Ohm J.-B. , Caffe-Treml M.
Published: September 2017

“Waxy” wheats (Triticum aestivum L.) produce endosperm starch devoid, or nearly so, of amylose. Waxy starch consists only of amylopectin, imparts unique cooking properties, and serves as an efficient substrate for the production of modified food starches. To expand the genetic variation of waxy wheats useful to Great Plains breeding programs, the USDA‐ARS, in cooperation with the University of Nebraska, developed and released 19 waxy winter wheats (Reg. No. GP‐1003, PI 677864 to Reg. No. GO‐1021, PI 677882) . Three of the waxy germplasm lines have soft endosperm texture; the remaining 16 lines have hard‐textured grain. The grain yields of six of the waxy winter wheat germplasm lines were not significantly different from the highest yielding nonwaxy cultivar (‘Freeman’). All but four waxy germplasm lines had grain yields statistically equal to that of the waxy winter wheat cultivar Mattern. Grain yield stability (or response to changing environments) of the waxy germplasm lines demonstrated similar trends to those of the nonwaxy controls. Grain yield observations and responses to changing production potentials argue against any yield drag associated with waxy starch and indicate potential for the development of additional and competitive cultivars.
Eigentimes and Very Slow Processes
Authors: Andresen Bjarne , Essex Christopher
Published: September 2017

We investigate the importance of the time and length scales at play in our descriptions of Nature. What can we observe at the atomic scale, at the laboratory (human) scale, and at the galactic scale? Which variables make sense? For every scale we wish to understand we need a set of variables which are linked through closed equations, i.e., everything can meaningfully be described in terms of those variables without the need to investigate other scales. Examples from physics, chemistry, and evolution are presented.
Techno-Economic Analysis of Solar Tower Aided Coal-Fired Power Generation System
Authors: Zhu Yong , Zhai Rongrong , Yang Yongping , Reyes-Belmonte Miguel
Published: September 2017

In this paper, we conduct a techno-economic analysis of a 1000 MWe solar tower aided coal-fired power generation system for the whole life cycle. Firstly, the power output (from coal and solar thermal energy) under variable direct normal irradiance and grid demand are studied. Secondly, a financial assessment is performed, including profits and losses of the plant project. Thirdly, sensitivity analysis is taken on some external factors that can affect the cost or profits and losses of the plant project. The results indicate that the project has high profits with an internal rate of return (IRR) of 8.7%. In addition, the effects of solar tower field cost, power purchase agreement (PPA) price of solar thermal electricity, coal price, and the interest rate of debt on the main criteria decrease gradually. Therefore, it is better to improve solar tower technology first, and then look for low-interest debts from banks to cope with the reduction of PPA price of solar thermal electricity and the increase of coal price. Despite the introduction of solar tower field increasing levelized cost of electricity (LCOE), it contributes to the reduction of CO2 capture cost compared to the case of standard coal-fired power plants.
Can We Predict the Efficacy of Anti-TNF-α Agents?
Authors: Lopetuso Loris , Gerardi Viviana , Papa Valerio , Scaldaferri Franco , Rapaccini Gian , Gasbarrini Antonio , Papa Alfredo
Published: September 2017

The use of biologic agents, particularly anti-tumor necrosis factor (TNF)-α, has revolutionized the treatment of inflammatory bowel diseases (IBD), modifying their natural history. Several data on the efficacy of these agents in inducing and maintaining clinical remission have been accumulated over the past two decades: their use avoid the need for steroids therapy, promote mucosal healing, reduce hospitalizations and surgeries and therefore dramatically improve the quality of life of IBD patients. However, primary non-response to these agents or loss of response over time mainly due to immunogenicity or treatment-related side-effects are a frequent concern in IBD patients. Thus, the identification of predicting factors of efficacy is crucial to allow clinicians to efficiently use these therapies, avoiding them when they are ineffective and eventually shifting towards alternative biological therapies with the end goal of optimizing the cost-effectiveness ratio. In this review, we aim to identify the predictive factors of short- and long-term benefits of anti-TNF-α therapy in IBD patients. In particular, multiple patient-, disease- and treatment-related factors have been evaluated.
Volume Shocks around Announcements in the Chinese Stock Market: An Ex-Post Earnings-Information-Based Study of Speculative Behavior
Authors: Chen Xiangdong , Wang Fei , Wang Wei , Hunstock Valerie
Published: September 2017

The Second Board Market is typical stock market for high tech companies in China. This paper discusses the relationship between trading volume and price changes in the case of high-tech listed companies in the Chinese Second-Board Stock Market. By using the basic concepts proposed by Kim and Verrecchia, and Kandel and Pearson, and contrasting them with ex-post information from earnings releases, the paper provides findings on the speculative behavior of informed traders with a volume shock premium. The paper suggests that these methods may be further applied to investigating investors’ behavior in speculation, especially for the high-tech-company-based Second-Board Stock Market during announcement periods.
Enhanced Plasmonic Wavelength Selective Infrared Emission Combined with Microheater
Authors: Ishihara Hiroki , Masuno Katsuya , Ishii Makoto , Kumagai Shinya , Sasaki Minoru
Published: September 2017

The indirect wavelength selective thermal emitter that we have proposed is constructed using a new microheater, demonstrating the enhancement of the emission peak generated by the surface plasmon polariton. The thermal isolation is improved using a 2 μm-thick Si membrane having 3.6 and 5.4 mm outer diameter. The emission at around the wavelength of the absorption band of CO2 gas is enhanced. The absorption signal increases, confirming the suitability for gas sensing. Against input power, the intensity at the peak wavelength shows a steeper increasing ratio than the background intensity. The microheater with higher thermal isolation gives larger peak intensity and its increasing ratio against the input power.
The Fabrication of All-Solid-State Lithium-Ion Batteries via Spark Plasma Sintering
Authors: Wei Xialu , Rechtin Jack , Olevsky Eugene
Published: September 2017

Spark plasma sintering (SPS) has been successfully used to produce all-solid-state lithium-ion batteries (ASSLibs). Both regular and functionally graded electrodes are implemented into novel three-layer and five-layer battery designs together with solid-state composite electrolyte. The electrical capacities and the conductivities of the SPS-processed ASSLibs are evaluated using the galvanostatic charge-discharge test. Experimental results have shown that, compared to the three-layer battery, the five-layer battery is able to improve energy and power densities. Scanning electron microscopy (SEM) is employed to examine the microstructures of the batteries especially at the electrode–electrolyte interfaces. It reveals that the functionally graded structure can eliminate the delamination effect at the electrode–electrolyte interface and, therefore, retains better performance.
Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC
Authors: Tegethoff Jana , Bischoff Roland , Saleh Sawsan , Blagojevic Biljana , Merz Karl-Heinz , Cheng Xinlai
Published: September 2017

Indirubin is an active component of the herbal ingredient ‘Danggui Longhui wan’, which was used for the treatment of inflammation and chronic myeloid leukemia in China. The recent study showed its derivative methylisoindigo (also known as meisoindigo) preferentially targeting cancer stem cells (CSCs) in interference with AMPK and LKB1, the cellular metabolic sensors. In this study, we screened the effect of meisoindigo on a panel of 300 protein kinases and found that it selectively inhibited Stat3-associated tyrosine kinases and further confirmed its activity in cell based assays. To gain a deeper insight into the structure–activity relationship we produced 7 bromo-derivatives exhausting the accessible positions on the bisindole backbone except for in the 4-position due to the space limitation. We compared their anti-proliferative effects on tumor cells. We found that 6-bromomeisoindigo showed improved toxicity in company with increased Stat3 inhibition. Moreover, we detected that 6-bromomeisoindigo induced apoptosis of 95% of CD133+ pancreatic cancer cells. Considering that CD133 is a common marker highly expressed in a range of CSCs, our results imply the potential application of 6-bromomeisoindigo for the treatment of CSCs in different types of cancers.
Developing Fine-Grained Actigraphies for Rheumatoid Arthritis Patients from a Single Accelerometer Using Machine Learning
Authors: Andreu-Perez Javier , Garcia-Gancedo Luis , McKinnell Jonathan , Van der Drift Anniek , Powell Adam , Hamy Valentin , Keller Thomas , Yang Guang-Zhong
Published: September 2017

In addition to routine clinical examination, unobtrusive and physical monitoring of Rheumatoid Arthritis (RA) patients provides an important source of information to enable understanding the impact of the disease on quality of life. Besides an increase in sedentary behaviour, pain in RA can negatively impact simple physical activities such as getting out of bed and standing up from a chair. The objective of this work is to develop a method that can generate fine-grained actigraphies to capture the impact of the disease on the daily activities of patients. A processing methodology is presented to automatically tag activity accelerometer data from a cohort of moderate-to-severe RA patients. A study of procesing methods based on machine learning and deep learning is provided. Thirty subjects, 10 RA patients and 20 healthy control subjects, were recruited in the study. A single tri-axial accelerometer was attached to the position of the fifth lumbar vertebra (L5) of each subject with a tag prediction granularity of 3 s. The proposed method is capable of handling unbalanced datasets from tagged data while accounting for long-duration activities such as sitting and lying, as well as short transitions such as sit-to-stand or lying-to-sit. The methodology also includes a novel mechanism for automatically applying a threshold to predictions by their confidence levels, in addition to a logical filter to correct for infeasible sequences of activities. Performance tests showed that the method was able to achieve around 95% accuracy and 81% F-score. The produced actigraphies can be helpful to generate objective RA disease-specific markers of patient mobility in-between clinical site visits.
Foliar Glyphosate Treatment Alters Transcript and Hormone Profiles in Crown Buds of Leafy Spurge and Induces Dwarfed and Bushy Phenotypes throughout its Perennial Lifecycle
Authors: Doğramaci Münevver , Anderson James V. , Chao Wun S. , Horvath David P. , Hernandez Alvaro G. , Mikel Mark A. , Foley Michael E.
Published: September 2017

Leafy spurge (Euphorbia esula L.) is an invasive weed of North America and its perennial nature attributed to underground adventitious buds (UABs) that undergo seasonal cycles of para‐, endo‐, and ecodormancy. Recommended rates of glyphosate (∼1 kg ha–1) destroy aboveground shoots but plants still regenerate vegetatively; therefore, it is considered glyphosate‐tolerant. However, foliar application of glyphosate at higher rates (2.2–6.7 kg ha–1) causes sublethal effects that induce UABs to produce stunted, bushy phenotypes. We investigated the effects of glyphosate treatment (±2.24 kg ha–1) on vegetative growth, phytohormone, and transcript profiles in UABs under controlled environments during one simulated seasonal cycle. Because shoots derived from UABs of foliar glyphosate‐treated plants produced stunted, bushy phenotypes, we could not directly determine if these UABs transitioned through seasonally induced endo‐ and ecodormancy. However, transcript abundance for leafy spurge dormancy marker genes and principal component analyses suggested that UABs of foliar glyphosate‐treated plants transitioned through endo‐ and ecodormancy. Glyphosate treatment increased shikimate abundance in UABs 7 d after treatment; however, the abundance of shikimate gradually decreased as UABs transitioned through endo‐ and ecodormancy. The dissipation of shikimate over time suggests that glyphosate's target site was no longer affected, but these changes did not reverse the altered phenotypes observed from UABs of foliar glyphosate‐treated leafy spurge. Transcript profiles further indicated that foliar glyphosate treatment significantly affected phytohormone biosynthesis and signaling, particularly auxin transport; gibberellic acid, abscisic acid and jasmonic acid biosynthesis; ethylene responses; and detoxification and cell cycle processes in UABs. These results correlated well with the available phytohormone profiles and altered phenotypes.
Relire un conte de Cyprian St. Cyr. L’amitié parfaite
Authors: Laurens Michel
Published: September 2017

À la fin d’un conte bref, Cyprian St. Cyr nous pose des questions auxquelles nous avons de la peine à répondre. Cet article examine tout d’abord la façon dont l’auteur a brouillé les pistes puis analyse le conte avec les outils de l’Analyse Transactionnelle. Il propose ensuite de sortir de l’allégorie pour retrouver les enjeux du conte. Ce chemin peut être une occasion de nous interroger sur nos réactions, ce qui était vraisemblablement le but de Cyprian St. Cyr.
« Regardez les allemands ! » : les racines de Lénine dans la social-démocratie européenne
Authors: Lih Lars T. , Guillibert Paul
Published: September 2017

Lars T. Lih, « Regardez les allemands ! » : les racines de Lénine dans la social-démocratie européenne À la fin du xix e siècle, le Parti social-démocrate allemand (SPD) propose un nouveau type de parti combinant des innovations techniques de mobilisations de masses (la campagne électorale, la « culture alternative », la presse de parti) avec un objectif révolutionnaire. Les sociaux-démocrates russes admiraient ce modèle, mais ils durent reconnaître qu’il leur manquait un point essentiel : la liberté politique nécessaire pour ce type de mobilisation. Ils durent innover pour adapter le modèle du SPD avec les conditions inhospitalières de la Russie. Dans ce cadre, Que faire ? de Lénine est moins une rupture théorique qu’un résumé d’une méthode empirique pensée avec les suggestions propres de Lénine pour atteindre cette étape, un parti national avec un leadership central.
« Les malentendus de l’hégémonie ». Gramsci dans le parti communiste français (1953-1983)
Authors: Di Maggio Marco
Published: September 2017

Le Parti communiste français s’est-il véritablement intéressé à l’œuvre d’Antonio Gramsci ? Notre article présente plusieurs étapes de la réception – discussion de l’œuvre du communiste italien au sein du PCF en soulignant des aspects méconnus, au-delà de la caricature habituelle selon laquelle Gramsci aurait été purement et simplement ignoré ou méprisé. Sans avoir une place centrale dans le « marxisme-léninisme » longtemps dominant, il a néanmoins été interrogé à plusieurs reprises et utilisé notamment par les intellectuels communistes afin de tenter une rénovation du marxisme.
Un Janus à deux visages. Patrimonialisations du religieux initiatique et discours de la tradition dans les musiques « tradi-modernes » du Gabon
Authors: Aterianus-Owanga Alice
Published: September 2017

Des années 1960 aux années 1990, plusieurs chanteurs se sont faits au Gabon les hérauts d’un projet de construction d’une identité gabonaise et africaine décolonisée participant d’un processus de façonnage de « traditions » et de « patrimoines ». Ils ont alors été, consciemment ou non, des acteurs majeurs de la patrimonialisation des sociétés initiatiques et de leur reconnaissance comme « tradition » à préserver. Fondé sur l’examen des trajectoires de trois de ces musiciens (Pierre-Claver Akendengué, Aziz’Inanga et Vyckos Ekondo), cet article démontre comment ces derniers élaborèrent un discours de valorisation de la « tradition » et participèrent à une « patrimonialisation ordinaire », en se nourrissant de voyages dans leurs villages d’origine, de confrontations avec les réseaux du panafricanisme ou de la world-music, des influences de l’africanisme ethnologique et de négociations stratégiques avec les politiques culturelles du régime d’Omar Bongo. L’étude multiscalaire et diachronique des mobilités musiciennes révèle ici les rapports ambigus entretenus avec l’idée de « tradition » dans le projet de construction d’un État gabonais moderne, et la manière dont ils se sont répercutés dans le processus de patrimonialisation des sociétés initiatiques.
« À propos d’ Eleven » : écriture de création, pratique de recherche
Authors: Dubos Anne
Published: September 2017

Eleven est une pièce en kit. L’écriture dramaturgique fonctionne sur le mode du « work in process ». Elle se travaille étape par étape, tout au long du cheminement de la compagnie. À partir de l’analyse des modalités de transmission des gestes de Kathakaḷi, l’auteure interroge la manière dont les techniques du corps traditionnelles évoluent : qu’arrive-t-il à la forme du geste lorsqu’il est transmis d’un corps à l’autre : de celui d’un danseur contemporain à un acteur amateur ? Et comment cartographier son changement dans l’espace et le temps ? Liée à un laboratoire du geste itinérant, la pièce met en scène l’hypothèse d’une nécessaire mobilité dans la conception de l’architecture des administrations patrimoniales.
Construire « par le bas » un patrimoine graphique ethnique en situation transnationale (Mexique-USA)
Authors: Hémond Aline
Published: September 2017

Le présent article s’attache aux processus de constitution des patrimoines graphiques ethniques, en partant de l’exemple des créations picturales sur papier d’écorce appelées «  amates  » réalisées par les peintres nahuaphones du sud-ouest du Mexique. Après mes travaux doctoraux réalisés sur ce sujet il y a 20 ans dans une perspective émique, je m’intéresse aujourd’hui à la rencontre entre des acteurs réseau (artistes indigènes) et des amateurs, collectionneurs, anthropologues et institutions transnationales qui ont permis la reconnaissance et la patrimonialisation de ces peintures. On se centrera ici notamment sur « l’extériorité légitimante » du Musée national d’art mexicain de Chicago. Cette institution muséale a permis de requalifier dans son propre espace d’action le statut des peintures et de leurs créateurs, créant ainsi un espace de traduction propre à la participation de la communauté hispanique à Chicago et à la réception dans les espaces sociaux caractéristiques du multiculturalisme aux États-Unis.
El habitus. Una revisión analítica
Authors: Martínez García José Saturnino
Published: September 2017

El objeto de este trabajo es presentar una visión analítica del concepto de habitus de Pierre Bourdieu. Para ello se repasa la definición del autor, luego se propone una mirada tanto explicativa como hermenéutica sobre las posibilidades de dicho concepto y, por último, se repasan las críticas que ha recibido, para intentar darles respuesta desde esta visión más analítica. Por un lado se muestra que puede asumir algunas de las realizadas por autores analíticos como Boudon y Elster. Por otro, se señala la mayor pertinencia de otras, como la falta de sensibilidad a los contextos sociales. El habitus posibilita un estudio objetivista de las prácticas sociales dotadas de sentido, mediante la combinación de mecanismos y de herramientas de tipo estructuralista para captar dicho sentido.
Ideología y aversión ideológica
Authors: Manzano-Arrondo Vicente
Published: September 2017

La ideología es un concepto controvertido que genera actitudes muy diversas. Este trabajo propone el constructo “aversión ideológica” para describir una de esas reacciones. La aversión ideológica consiste en la combinación de dos componentes: rechazo de las ideologías y defensa de actuaciones políticas exclusivamente técnicas. Previamente se define la ideología como una forma de ver, preferir y actuar en el mundo, que surge de la relación entre dos dimensiones: encuadres sociales y necesidades. La aversión ideológica responde también a una forma de estar en el mundo, que permite mantener funcionamientos sociales y satisfacer necesidades psicológicas. Este documento ofrece también un instrumento para medir el concepto. El cuestionario consta de diez ítems, cinco para cada uno de los dos componentes de la aversión ideológica. Se ha construido a partir de una muestra on line de n = 650, y ha sido probada en una muestra cara a cara de n = 340, mostrando buenas características psicométricas.
Cutting Edge: Endogenous IFN-β Regulates Survival and Development of Transitional B Cells
Authors: Hamilton Jennie A. , Wu Qi , Yang PingAr , Luo Bao , Liu Shanrun , Hong Huixian , Li Jun , Walter Mark R. , Fish Eleanor N. , Hsu Hui-Chen , Mountz John D.
Published: September 2017

The transitional stage of B cell development is a formative stage in the spleen where autoreactive specificities are censored as B cells gain immune competence, but the intrinsic and extrinsic factors regulating survival of transitional stage 1 (T1) B cells are unknown. We report that B cell expression of IFN-β is required for optimal survival and TLR7 responses of transitional B cells in the spleen and was overexpressed in T1 B cells from BXD2 lupus-prone mice. Single-cell gene expression analysis of B6 Ifnb+/+ versus B6 Ifnb–⁄– T1 B cells revealed heterogeneous expression of Ifnb in wild-type B cells and distinct gene expression patterns associated with endogenous IFN-β. Single-cell analysis of BXD2 T1 B cells revealed that Ifnb is expressed in early T1 B cell development with subsequent upregulation of Tlr7 and Ifna1. Together, these data suggest that T1 B cell expression of IFN-β plays a key role in regulating responsiveness to external factors.
Accuracy of Three-dimensional Cone Beam Computed Tomography Digital Model Measurements Compared with Plaster Study Casts
Authors: Ali Shuaib Al , Premjani Pratik , Al-Mulla Anas H. , Ferguson Donald J.
Published: September 2017

Purpose

The purpose of this study was to assess the accuracy of three-dimensional (3D) cone beam computed tomography (CBCT) study casts by comparing with direct measurements taken from plaster study casts.

Materials and Methods

The dental arches of 30 patient subjects were imaged with a Kodak 9300 3D CBCT devise; Anatomodels were created and in vivo 5 imaging software was used to measure 10 dental arch variables which were compared to measurements of plaster study casts.

Results:

Three of the 10 variables, i.e., overbite, maxillary intermolar width, and arch length, were found significantly smaller (P < 0.05) using the Anatomodels following nonparametric Wilcoxon signed-rank testing. None of the differences found in the study averaged <0.5 mm.

Conclusions

3D CBCT imaging provided clinically acceptable accuracy for dental arch analysis. 3D CBCT imaging tended to underestimate the actual measurement compared to plaster study casts.
Class III Molar Finish as a Different Treatment Approach to Correct an Adolescent Class II Patient Using Headgear, Forsus, and Lower Arch Extraction
Authors: Koya Shafees , Mascarenhas Rohan , Rahul R. S. , Ajeesha Nair J. S.
Published: September 2017

Various treatment strategies are adopted to correct a Class II malocclusion depending on the age, the amount of remaining growth and severity of malocclusion. Single arch extraction of the lowers is rarely done in a Class II malocclusion. The following case report describes an alternate treatment approach of an adolescent Class II patient treated with a combination of headgear, fixed functional appliance (forsus), and single arch extraction only in the lower arch. The case was finished in a Class III molar and a Class I canine relationship. The results were stable in 3 years follow-up.
Adjuvant Gemcitabine-Oxaliplatin (GeMOX) after Curative Surgery in High-risk Patients with Cholangiocarcinoma
Authors: Paule Bernard , Andreani Paola , Bralet Marie-Pierre , Guettier Catherine , Adam René , Castaing Denis , Azoulay Daniel
Published: September 2017

Background

There is no standard adjuvant chemotherapy to prevent recurrent cholangiocarcinoma (CCA), a rare cancer with poor prognosis. We assessed the efficacy and safety of GEMOX on intrahepatic and hilar CCA with high-risk factors after curative surgery.

Patients and Methods

Twenty two patients (mean age: 57 years old) with CCA received 6 cycles of GEMOX: gemcitabine 1,000 mg/m2 on day 1 and oxaliplatin 85 mg/m2 on day 2, q3w after a curative surgery.

Results

All patients completed 6 cycles of GEMOX. EGFR membranous expression was present in 20 CCA. The 5-year survival rate was 56% (CI 95%: 25.7–85.4); 2-year disease free survival rate was 28% (CI 95%: 3.4–52.6). Median time to progression was 15 months. The rate of recurrence after surgery and chemotherapy was 63% (14/22). Two patients died of disease progression. Twelve patients received cetuximab/GEMOX at the time of relapse. Six died after 12 months (9–48 months), three are still alive suggesting a clinical applicability of EGFR inhibitors in CCA.

Conclusion

Adjuvant chemotherapy with GEMOX alone seems ineffective in intrahepatic and hilar CCA with a high risk of relapse. Additional studies including targeted therapies to circumvent such poor chemosensitivity are needed.
The ‘Pokemon’ (ZBTB7) Gene: No Evidence of Association with Sporadic Breast Cancer
Authors: Salas Antonio , Vega Ana , Milne Roger L. , García-Magariños Manuel , Ruibal Álvaro , Benítez Javier , Carracedo Ángel
Published: September 2017

It has been proposed that the excess of familiar risk associated with breast cancer could be explained by the cumulative effect of multiple weakly predisposing alleles. The transcriptional repressor FBI1, also known as Pokemon, has recently been identified as a critical factor in oncogenesis. This protein is encoded by the ZBTB7 gene. Here we aimed to determine whether polymorphisms in ZBTB7 are associated with breast cancer risk in a sample of cases and controls collected in hospitals from North and Central Spanish patients. We genotyped 15 SNPs in ZBTB7, including the flanking regions, with an average coverage of 1 SNP/2.4 Kb, in 360 sporadic breast cancer cases and 402 controls. Comparison of allele, genotype and haplotype frequencies between cases and controls did not reveal associations using Pearson's chi-square test and a permutation procedure to correct for multiple test. In this, the first study of the ZBTB7 gene in relation to, sporadic breast cancer, we found no evidence of an association.