bluuebunny/crossref_metadata_2025 huggingface dataset:
Expectations of Anesthesiology and Intensive Care Professionals Toward Artificial Intelligence: Observational Study (Preprint)
Authors: Kloka Jan Andreas , Holtmann Sophie C , Nürenberg-Goloub Elina , Piekarski Florian , Zacharowski Kai , Friedrichson Benjamin
Published: November 2022

BACKGROUND

Artificial intelligence (AI) applications offer numerous opportunities to improve health care. To be used in the intensive care unit, AI must meet the needs of staff, and potential barriers must be addressed through joint action by all stakeholders. It is thus critical to assess the needs and concerns of anesthesiologists and intensive care physicians related to AI in health care throughout Europe.

OBJECTIVE

This Europe-wide, cross-sectional observational study investigates how potential users of AI systems in anesthesiology and intensive care assess the opportunities and risks of the new technology. The web-based questionnaire was based on the established analytic model of acceptance of innovations by Rogers to record 5 stages of innovation acceptance.

METHODS

The questionnaire was sent twice in 2 months (March 11, 2021, and November 5, 2021) through the European Society of Anaesthesiology and Intensive Care (ESAIC) member email distribution list. A total of 9294 ESAIC members were reached, of whom 728 filled out the questionnaire (response rate 728/9294, 8%). Due to missing data, 27 questionnaires were excluded. The analyses were conducted with 701 participants.

RESULTS

A total of 701 questionnaires (female: n=299, 42%) were analyzed. Overall, 265 (37.8%) of the participants have been in contact with AI and evaluated the benefits of this technology higher (mean 3.22, SD 0.39) than participants who stated no previous contact (mean 3.01, SD 0.48). Physicians see the most benefits of AI application in early warning systems (335/701, 48% strongly agreed, and 358/701, 51% agreed). Major potential disadvantages were technical problems (236/701, 34% strongly agreed, and 410/701, 58% agreed) and handling difficulties (126/701, 18% strongly agreed, and 462/701, 66% agreed), both of which could be addressed by Europe-wide digitalization and education. In addition, the lack of a secure legal basis for the research and use of medical AI in the European Union leads doctors to expect problems with legal liability (186/701, 27% strongly agreed, and 374/701, 53% agreed) and data protection (148/701, 21% strongly agreed, and 343/701, 49% agreed).

CONCLUSIONS

Anesthesiologists and intensive care personnel are open to AI applications in their professional field and expect numerous benefits for staff and patients. Regional differences in the digitalization of the private sector are not reflected in the acceptance of AI among health care professionals. Physicians anticipate technical difficulties and lack a stable legal basis for the use of AI. Training for medical staff could increase the benefits of AI in professional medicine. Therefore, we suggest that the development and implementation of AI in health care require a solid technical, legal, and ethical basis, as well as adequate education and training of users.
A machine learning predict model for one-and three-year risk of lifestyle diseases: A retrospective analysis of nationwide database. (Preprint)
Authors: Yang Yi-Chu , Chou Wan-Yun
Published: November 2022

BACKGROUND

Lifestyle diseases, specifically cardiovascular disease, diabetes, chronic obstructive pulmonary disease (COPD), chronic liver disease and chronic kidney disease (CKD), have major impacts on health and well-being and are responsible for around 74% of global deaths. However, studies related to the early prediction of lifestyle diseases using the National Health Insurance Research Database (NHIRD) laboratory databases are rare.

OBJECTIVE

We demonstrate that with the proper data set and learning strategies deep learning models for one- and three-year risk of lifestyle diseases based on their historical claims to improve prevention and control, therefore deliver significant benefits.

METHODS

A total of 133,519 patients and 1,548,610 clinical records were extracted from the NHIRD over 10 years were obtained to generate a data set for outcome prediction. Our study is the first published research which access the NHI laboratory databases. To better interpret the results of laboratory tests, the laboratory database was linked to outpatient claims and inpatient claims of NHIRD. In our study, we use K-means Clustering in Machine Learning. To process the learning data, the K-means algorithm in data mining starts with 80% of randomly selected subjects, which are used as the train set for every cluster, and then 20% of the rest subjects performs as the test set. We use the t-distributed Stochastic Neighbor Embedding (t-SNE), which visualizes the high dimension data with imbalanced and insufficient data to improve the accuracy, sensitivity, and specificity of predicting models that represents a subject. We propose a joint deep neural networks (DNN) clustering framework to calculate the difference between subjects and to predict the primary and secondary outcomes. The F score and area under the receiver operating characteristic (AUROC) were our main evaluation metrics.

RESULTS

We achieved an AUROC of 1-year and 3-year predict model of diabetes for 0.80 and 0.79, cardiovascular disease for 0.72 and 0.73, CKD for 0.89 and 0.87, chronic liver disease for 0.74 and 0.73, and COPD for both 0.78.

CONCLUSIONS

This study was the first use of NHIRD laboratory test data and demonstrated the potential of predicting future outcomes for lifestyle diseases by machine learning. The results showed that our proposed approach could effectively alleviate data imbalance problems and train a better model for outcome prediction.
The Formation and Development of Japanese Craftsmanship
Authors: Zuo Linmei
Published: November 2022

Japanese craftsmanship is an important resource of Japanese industrial culture. The Japanese manufacturing industry has a global reputation and strong competitiveness and influence, and the artisan spirit is one of the “secret weapons” that has made the Japanese manufacturing industry strong. The evolution of Japanese craftsmanship in different historical periods can further enrich the connotation of craftsmanship and deepen people’s understanding of craftsmanship, which is of positive significance to all countries in cultivating and promoting craftsmanship and improving the service capability of various industries.
Inclusión financiera en México y Covid-19: cambios en indicadores estatales
Authors: Espinosa Espíndola Mónica Teresa , Maceda Méndez Adolfo
Published: November 2022

Objetivo: identificar los cambios en un grupo de indicadores de inclusión financiera en los Estados de México, comparando su situación en el año previo a la pandemia de Covid-19 con su situación en el primer año de esta.   
Diseño metodológico: se consideraron 14 indicadores de inclusión financiera, reportados por la Comisión Nacional Bancaria y de Valores por Estados, y se comparó la información de ellos correspondiente al año previo a la pandemia de Covid-19 con la del primer año de esta pandemia, para determinar qué cambios hubo en ellos.   
Resultados: del año 2019 al año 2020 se identificó un aumento en el valor de las correlaciones existentes entre los siguientes indicadores: tarjetas de débito, de crédito, transacciones en terminal punto de venta y cuentas transaccionales tradicionales. Tamaulipas y Aguascalientes tuvieron cambios significativos en algunos indicadores de inclusión financiera.   
Limitaciones de la investigación: los datos analizados son únicamente de la Comisión Nacional Bancaria y de Valores y corresponden a la información proporcionada a esta por los entes del sistema financiero. Otros organismos emplean datos obtenidos mediante encuestas trianuales.   
Hallazgos: a nivel nacional, entre los indicadores de inclusión financiera analizados, los más afectados durante la pandemia de Covid-19 fueron los de uso, mientras que, a nivel estatal, los Estados con menor inclusión financiera tienen más bajos niveles en los indicadores de acceso que en los de uso. Con la metodología empleada se detectaron y analizaron gráficamente los cambios registrados en los indicadores de inclusión financiera analizados.
Salud y medio ambiente
Authors: Moreno Sánchez Ana Rosa
Published: November 2022

Since the Industrial Revolution, human activities have caused various and significant effects on the planet widely investigated and reported. Human beings and the rest of living beings have a permanent interdependence with the environment, which has become more evident today. Damage to the quality of water, air and soil, coupled with the progressive deterioration and loss of ecosystems and the effects on flora and fauna, have led to changes that translate into dangers and risks of various kinds and im portance for human health, either short term or long term.
These environmental changes are accompanied and enhanced by social, economic, cultural and political factors whose impacts on health are manifested at the local, regional and even global levels. This article describes the main environmental changes and their adverse effects on health, highlighting the importance of physicians considering them in their daily dealings with patients and their families, partic ularly when vulnerable populations have been identified. It concludes with the recommendation that the health sector show greater interest in the environment and health issue, adopting leadership to strengthen environmental public health programs with intersectoral and interdisciplinary approaches. Let’s hope that the health field and its environmental base constitute the comprehensive training of human resources and promote research that provides ele ments to define and implement successful public policies. Keywords: Global environmental change; human health
Síndrome de teratoma creciente. Reporte de caso
Authors: Pérez Gordillo Fernando , Sierra Laura
Published: November 2022

Growing teratoma syndrome is an entity in which there are histological modifications of an immature malignant tera toma treated with chemotherapy and with negative tumor markers to a mature teratoma. Given the low incidence of the pathology, a case of a patient with a history of ovarian tumors with report of immature teratoma which was ex tracted is reported. The patient received chemotherapy with normalization of serum markers. Subsequently she present ed a pelvic, retroperitoneal and hepatic tumor that again required surgical intervention with pathological report of mature cystic teratoma. Key words: Teratoma; tumor markers; chemotherapy; non-semi nomatous germ cell tumor; tomograph
Spectral and FTIR Analysis of Tm3+ Doped in Zinc Lithium Tungsten Sodalime Borotellurite Glasses
Authors: Meena S. L.
Published: November 2022

Abstract: Glass sample of Zinc Lithium Tungsten Sodalime Borotellurite: (35-x) TeO2:10ZnO:10Li2O:10WO3:10CaO:10Na2O:15B2O3:xTm2O3. (where x=1,1.5 and 2 mol%) have been prepared by meltquenching technique. The amorphous nature of the prepared glass samples was confirmed by X-ray diffraction. Optical absorption ,fluorescence and FTIR spectra were recorded at room temperature for all glass samples. Judd-Ofelt intensity parameters Ωλ (λ=2, 4 and 6) are evaluated from the intensities of various absorption bands of optical absorption spectra. Using these intensity parameters various radiative properties like spontaneous emission probability, branching ratio, radiative life time and stimulated emission cross– section of various emission lines have been evaluated
Leachate Characterization Generated from Municipal Solid waste at Landfill Site Ghazipur, New Delhi
Authors: Chaudhary Sharad
Published: November 2022

Abstract: The management of municipal solid waste (MSW) is one of the key environmental issues facing Indian cities, mostly as a result of the country's growing industrialisation and urbanisation. According to numerous studies, open dumps and landfills are used to dispose of around 90% of solid waste in an improper manner. Pollutants can escape a poorly constructed landfill in a number of ways. Leachate can escape from a landfill or dumpsite and contaminate groundwater and surface water if the soil above or below it is porous. Therefore, In this paper an attempt is made to characterize the leachate produced by municipal solid waste dumping site of Ghazipur, New Delhi which is located at Latitude: 28° 37' 30.8784". Longitude: 77° 19' 40.764" near the Delhi-UP border. In this investigation, about 12 leachate parameters were identified. Three sample sites at the bottom of the landfill, spaced 7 metres apart, were used to characterise the leachate samples. All of the leachate samples had an acidic pH value ranging from 6.24 to 6.88, it is discovered. All of the sample’s conductivity and total dissolved solids ranged from 567 to 1945 S/cm and 513 to 1289 ppm respectively. Similar dissolved ions such chloride, calcium, sodium, nitrate, and potassium were found in the leachate sample. The majority of the ions were discovered to be above the standards-permitted level. The present study concludes that characterization of landfill leachate is important to identify the most critical pollutants present in the leachate and thereby to introduce suitable and applicable technologies such as in-situ impermeable barriers etc.
REDUÇÃO DE PERDAS DE ENERGIA POR MEIO DA GESTÃO ORGANIZACIONAL: ABORDANDO A MELHORIA DE PROCESSOS
Authors: Rocha Santos Emanuel , Nascimento Suellen , Vasconcelos Silva Simone
Published: November 2022

Objetivo: Este artigo tem por objetivo propor melhorias no processo de inspeção e regularização das fraudes na medição em uma distribuidora de energia do estado do Rio de Janeiro, visando o combate às perdas não técnicas. Para tal, foi utilizada a modelagem do processo por meio da notação BPMN (Business Process Model Notation) integrada às ferramentas da qualidade.
Método / abordagem: A metodologia de pesquisa foi dividida em: identificação de trabalhos relacionados na literatura, análise de dados e documentos da organização estudada em relação ao processo que será abordado, modelagem do processo de negócio por meio da notação BPMN (Business Process Model Notation), análise de possíveis melhorias por meio da aplicação de ferramentas da qualidade, desenho do processo após as melhorias, e análise dos resultados obtidos com a implantação das melhorias no processo.
Principais resultados: A implementação das melhorias detectadas acarretou uma melhora significativa dos indicadores de ganhos de energia, alcançando pico de 27% de aumento, além disso, observou-se uma redução da reincidência de fraude de energia por meio das medidas aplicadas como resultado deste trabalho, atingindo o objetivo proposto.
Contribuições metodológicas / sociais / gerenciais: Com os resultados obtidos pode-se concluir que a modelagem de processos integrada à aplicação de ferramentas da qualidade é essencial na melhoria dos processos de negócio.
Originalidade / relevância: O trabalho traz originalidade com a aplicação da metodologia proposta no âmbito do serviço de combate às perdas em distribuição de energia elétrica, tema de grande relevância para o setor.
Introduction from the Editors/ Introduction des rédacteurs
Authors: North Andrew , Trudeau Christian , Jacobs Heidi
Published: November 2022

Welcome to the Journal of Canadian Baseball, a joint initiative of the University of Windsor and the Centrefor Canadian Baseball Research. We aim to feature under one cover the research of two contributingcommunities, both the scholarly of the academics and the popular of the baseball historians. From both the Grovesand the Fields, if you will.
Coloured Diamonds: Integrated Baseball in the Canadian Expeditionary Force 1914-1918
Authors: Dame Stephen
Published: November 2022

For the duration of the First World War, the Canadian Expeditionary Force was officially integratedin principle, but stubbornly segregated in practice. Black soldiers, having fought to fight, discoveredthat relationships forged in the trenches often shook ingrained prejudices. If there was no such thingas an atheist in a foxhole, then the same could be said of bigots and baseball diamonds. Integrated baseball inthe CEF was more common than extant histories suggest. Black and white soldiers played against each other,and shared benches alike, when such desegregated diamonds were still exceedingly rare on the home front.
The Effectiveness of Homogeneous Classifier Ensembles on Customer Churn Prediction in Banking, Insurance, and Telecommunication Sectors
Authors: KİLİMCİ Zeynep Hilal
Published: November 2022

The prediction of customer churn is a big challenging problem for companies in different sectors such as banking, telecommunication, and insurance. It is a crucial estimation for many businesses since obtaining new customers frequently costs more than holding present ones. For this reason, analysts and researchers are focus on to investigate reasons behind of customer churn analyzing behaviors of them. In this paper, an ensemble-based framework is proposed to predict the customer churn in various sectors, namely banking, insurance, and telecommunication. To demonstrate the effectiveness of proposed ensemble framework, k-NN, logistic regression, naïve Bayes, support vector machine, decision tree, random forest, multilayer perceptron algorithms are employed. Moreover, the effects of the inclusion of feature extraction process are investigated. Experiment results indicate that that random forest algorithm is capable to predict churn customers with 89.93% of accuracy in banking, 95.90% of accuracy in telecommunication, and 77.53% of accuracy in insurance sectors when feature extraction procedure is carried out.
Effects of Green Roof in Reducing Surface Temperature and Addressing Urban Heat Island in Tropical Climate of Malaysia
Authors: Abdul Rahman Afzan , Mohamed Zaid Suzaini , Mohammad Shuhaimi Nur Dinie Afiqah
Published: November 2022

Urban heat island (UHI) in cities across Malaysia has worsened due to rapid development and construction. Previous research highlight temperature difference between Putrajaya and its suburban neighbouring area is as high as 5˚C. Green roofs in urban areas can be used as a green intervention strategy to reduce UHI impact by increasing air moisture and surface wetness through its plants, which consequently decreases surrounding air and surface temperature. Green roofs also provide additional insulation that reduces heat transfer into buildings, therefore reducing cooling demand and operational energy in buildings. Conventional building roofs in tropical climate have measured surface temperature up to 60˚C, compared to surrounding irrigated grass and water bodies that are measured as low as 15˚C. This paper compared surface temperatures of green roof and conventional non-green roof case studies in a tropical climate setting, to combat urban heat island effect. A triangulation technique was adopted, using a case study analysis with an in-depth structured interview and physical fieldwork investigation. The findings concluded that green roofs had significantly lower surface temperature compared to non-green flat roof. This paper provides evidence that supports green roof as a green intervention strategy in reducing urban heat island and encourage building designers to maximize under-utilized spaces of roofs to increase urban greenery coverage.
Accessible Tourism Perspective in Tourist Destination of Dusun Semilir, Indonesia
Authors: Sari Suzanna Ratih , Hilmy Muhammad Fariz , Murti Nindita Kresna
Published: November 2022

Dusun Semilir is one of the largest tourist destinations in Central Java-Indonesia due to its attractive building design that increases the curiosity of tourists. However, there are several implementations of tourist attraction design, accessibility, and supporting facilities that do not consider the humanist aspects such as non-sloping paths, too high stairs, which hindered those with limitations including the elderly and disabled, from accessing and enjoying the atmosphere. This indicated that the universal design approach is less than optimal. Therefore, this study aims to maintain tourist comfort by providing a universal design perspective for a tourist destination. Qualitative methods were used to explore universal design-related phenomena and problems in order to implement the design concepts that are accessible to everyone. Furthermore, observations and interviews with purposive sampling techniques were used as the instruments while descriptive analysis techniques were conducted to determine the comfort of tourists based on the universal design aspect. The output of this study is the importance of using universal design to create accessible tourism.
Sustainable Architecture in the Urban Studies on Walkability in Public Housing
Authors: G. T Tee , A.M.R Aminuddin , A.S Sarly , S. Mohmad Shukri
Published: November 2022

This research aims to observe the existing streetscapes feature related to walkability in the area of The People’s Housing Program in Kerinchi which serves as part of the Government Program for the resettlement of squatters and to fulfill the shelter needs of the low-income group (bottom 40%) in Malaysia. The stakeholder’s perception of the effectiveness of the existing streetscape feature will be collected and analyzed.The study employs a quantitative approach, data collection is done via on-site study and survey questionnaires. Streetscape features were analyzed from four criteria – enjoyment, safety, comfort, and accessibility. This study identified most of the respondents will spend less time walking due to lacking enjoyment (55.33%), exposed physical safety (42.30%), poor sanitation and street maintenance (54.36%),and poor walkability design for special-needs people (53.60%). The outcome of the research findings suggests several methods in improving walkability by enhancing the walking environment and facilities, implementation of the pedestrian-only zone, congestion pricing, and more active participation by governing bodies.
Ansiedade Matemática:
Authors: De Campos Ana Maria Antunes
Published: November 2022

As dificuldades relacionadas à aprendizagem matemática podem ser causadas pela ansiedade matemática, que é considerada uma aversão específica à matemática. Essa fobia é uma resposta negativa aos estímulos numéricos que modifica o estado cognitivo, fisiológico e comportamental da criança e do adolescente. Dessa forma, este artigo, concentra-se em compreender o que a literatura tem discutido sobre essa temática na Educação Básica nos Anos Iniciais. Para compor este trabalho realizamos um levantamento das produções divulgadas nas bases de dados bibliográficas. O primeiro critério para identificação das pesquisas foi a presença, no título, no resumo e nas palavras-chave, dos descritores “ansiedade matemática”; “math anxiety”; “mathematical anxiety”; o segundo critério foi o acesso aberto à publicação. Os resultados revelam que a ansiedade matemática tem suas raízes na primeira infância, quando se inicia a comparação de desempenho, podendo afetar negativamente não apenas no comportamento diante da matemática, mas na maneira que os estudantes aprendem a matemática. A exposição sustentada à estímulos matemáticos podem reduzir a ansiedade matemática, tanto nos aspectos comportamentais quanto nos aspectos cognitivos.
Changes in the Physicochemical Properties of Rapeseed-derived Protein Complexes During Enzyme-Assisted Wet Milling
Authors: Alpiger Simone , Corredig Milena
Published: November 2022

Oilseeds need to be exploited not only for the oil but also as a source
of functional protein-rich ingredients for food. This work evaluated the
physicochemical properties of the colloidal fraction resulting from wet
milling of rapeseed, used as model oilseed. The extraction was conducted
either at natural pH (5.7) or at alkaline pH (8.5), with or without
addition of a commercial pectinase. The slurry was mixed for 4 h at room
temperature, and then pressed at the same pH or after shifting to
alkaline/acidic pH. The resulting extract, rich in oil and protein
particles, showed differences in particle size, microstructure and
composition. The oil and protein yields in the extract (in relation to
the amount originally in the oilseed) ranged between 60 and 70 %, with
a significant increase in protein recoveries with addition of pectinase,
regardless of the pH. A protein concentrate, containing between 25 and
42 % protein on dry matter, depending on the treatment was obtained
after centrifugation, together with a fiber precipitate and an oil
fraction. The composition of the concentrates varied, with the highest
purity found for extracts at pH 5.7, showing a nearly complete physical
separation of the oleosomes by low speed centrifugation. All
concentrates showed similar protein composition, as analyzed by gel
electrophoresis. The amino acid composition was also similar amongst the
treatments. This work evidences the critical role played by biopolymers’
interactions in forming different colloidal structures, with clear
consequences on the functionality of the final ingredient.
Research on optimization of ecological security patterns based on natural and cultivated land disturbance
Authors: Ma Tianyue , Li Jing , Bai Shuang , Chang Fangzhe , Jiang Zhai , Yan Xingguang , Shao Jiahao
Published: November 2022

In previous research on the construction of ecological security patterns
(ESPs), the positioning characteristics of urban development were rarely
considered, resulting in the identification of key conservation areas
that are insufficiently thorough to support the ecological security of
the entire region and the overall development of urban functions. To
solve this problem, this research created a
“quality-importance-connectivity-balance” framework to identify ESPs,
and chose Liaocheng City (LC), a typical main agricultural production
area in China’s Shandong Province’s western plain, as the study area.
The swat model was used to determine security levels from a watershed
perspective using an integrated resistance assessment method that
accounts for topography, human activities, distance, and agricultural
environmental impacts. Then, the minimal cumulative resistance (MCR) and
gravity models were used to identify and categorize corridors, while
pinch points and barrier points were obtained by circuit theory.
Finally, the comprehensive quality of cultivated land and the pattern of
coordination between agriculture and ecology were divided. The results
demonstrated that, as a result of the fragmentation of cultivated land,
LC exhibited plain resistance characteristics and identified 181.16 km2
of sources and 174 potential corridors. A “six cores-seven belts-three
zones” optimization pattern was constructed based on the components of
ESPs and the distribution of cultivated land comprehensive quality. This
study presents a novel approach for measuring ESPs and is an essential
resource for ecological conservation and regional development planning
in agroecologically complex regions.
Fatigue failure analysis and experimental research on the connecting rod of high-power marine diesel engine
Authors: Zhu Jialiang , Wang Guixin , Chen Guangku , Gao Wenxiang , Li Xiaobo
Published: November 2022

The connecting rod of high-power marine diesel engine fractured near the
bolt hole before reaching the life expectancy, in which the typical
fatigue fracture characteristics were found. The study improved the
traditional simulation method of connecting rod to simulate the diesel
engine more realistically. On the basis of the crank train model,
various relevant boundary conditions are considered by introducing
membrane mesh. The simulation results are consistent with the failure
analysis of diesel engine, which verifies the correctness of simulation
method proposed in this research. The material used for the connecting
rod is 42CrMoA, which fatigue performance can only be obtained through
fatigue testing. The yield limit of the material is 950MPa and an exact
S-N curve is obtained by the fatigue test. This paper combined the
material fatigue property with dynamics simulation, and found that the
minimum safety factor of connecting rod occurs 5°CA after the TDC and is
1.33, which is satisfied but not sufficient. Meanwhile, the relationship
between the bolt preload force and the stress level was investigated as
the damage of connecting rod appears in the bolt hole region. Various
preload forces were analyzed and the safety factor increased from 1.33
to 1.97 when the preload force is set to 80kN, which increased by 43%.
In addition, the influence law between preload force and stress as well
the empirical formula between them were summarized. This research not
only provides a new method for the selection of preload force, but also
allows rapid analysis of the connecting rod stress without complex
finite element models in the conceptual design stage.
Effect of coiling temperature on the structure and properties of thermo-mechanically rolled S700MC steel
Authors: Oktay S. , di Nunzio , Cesile M.C. , Davut K. , Şeşen M.K.
Published: November 2022

The boron-free S700MC steel is usually produced by exploiting the properties of a ferrite-bainite mixed microstructure formed by coiling the strips at a temperature of about 450?C, i.e.below the bainite starting temperature. With the aim of further enhancing the mechanical properties of 6 to 10 mm thick strips, industrial tests were carried out at a coiling temperature of 600?C to promote the formation of a structure of ferrite and carbides, which is also acceptable for this type of steel. Unexpectedly, a microstructure composed of ferrite and martensite was obtained. Compared to the ferritic-bainitic grade, the new structure is characterized by a slight decrease of the yield point but by an increase of the ultimate tensile strength by no less than 80 MPa, with a transition from a quasi-discontinuous to a clearly continuous yielding behaviour. Accordingly, the ratio of yield strength to tensile strength decreases from 0.90 to 0.75 and the impact energy decreases by 35 J and 60 J for the two gauge levels, respectively. The mechanical behaviour of the strips coiled at high temperature is explained as a direct consequence of the dual phase structure with a hard phase interspersed in a soft ferrite matrix. The presence of martensite is explained by the so-called incomplete bainite reaction. The partial transformation into ferrite after coiling and the long time required for the coil to cool down stabilize the untransformed austenite due to the carbon enrichment making bainite formation at lower temperatures impossible.
Interdiffusion coefficient and atomic mobility for fcc Ag-Cu-Mg phase at 1073 K
Authors: Du C.-B. , Huang S.-P. , Min Q.-H. , Liu Y.-L. , Wen S.-Y.
Published: November 2022

In this work, the interdiffusion coefficient and atomic mobility for the fcc Ag-Cu-Mg phase at 1073 K were investigated by combining diffusion couple experiments and calculations. Based on the experimental composition profiles, the diffusion coefficients at the intersections of the diffusion paths were calculated using the Matano-Kirkaldy method. Using the thermodynamic descriptions available in the literature, the atomic mobilities for the fcc Ag-Cu-Mg phase were automatically optimized by numerical inverse method integrated with the CALTPP (CALculation of ThermoPhysical Properties) program. Moreover, the obtained atomic mobilities were confirmed to be reliable by good agreements between the model-simulated and the measured composition profiles. In addition, three-dimensional surfaces were presented for the interdiffusion coefficient, activation energy, and frequency factor. The presently obtained atomic mobilities can be incorporated into the diffusion database for Ag-based alloys, which can contribute to microstructure simulation and materials design.
Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy
Authors: Yadav Yogesh , Romeres Davide , Cobelli Claudio , Dalla Man Chiara , Carter Rickey , Basu Ananda , Basu Rita
Published: November 2022

To assess the diurnal patterns of postprandial glucose tolerance and insulin sensitivity, 19 subjects with type 2 diabetes (8 women; 60 ± 11 years; BMI 32 ± 5 kg/m2) and 19 anthropometrically matched subjects with no diabetes (ND; 11 women; 53 ± 12 years; BMI 29 ± 5 kg/m2) were studied during breakfast (B), lunch (L), and dinner (D) with identical mixed meals (75 g carbohydrates) on 3 consecutive days in a randomized Latin square design. Three stable isotopes of glucose were ustilized to estimate meal fluxes, and mathematical models were used in estimating indices of insulin action and β-cell function. Postmeal glucose excursions were higher at D versus B and at D versus L in type 2 diabetes (P < 0.05), while in ND they were higher at D versus B (P = 0.025) and at L versus B (P = 0.04). The insulin area under the curve was highest at B compared with L and D in type 2 diabetes, while no differences were observed in ND. Disposition index (DI) was higher at B than at L (P < 0.01) and at D (P < 0.001) in ND subjects, whereas DI was low with unchanging pattern across B-L-D in individuals with type 2 diabetes. Furthermore, between-meal differences in β-cell responsivity to glucose (F) and insulin sensitivity (SI) were concurrent with changes in the DI within groups. Fasting and postmeal glucose, insulin, and C-peptide concentrations, along with estimates of endogenous glucose production (EGP), Rd, SI, F, hepatic extraction of insulin, insulin secretion rate, extracted insulin, and DI, were altered in type 2 diabetes compared with ND (P < 0.011 for all). The data show a diurnal pattern of postprandial glucose tolerance in overweight otherwise glucose-tolerant ND individuals that differs from overweight individuals with type 2 diabetes. The results not only provide valuable insight into management strategies for better glycemic control in people with type 2 diabetes, but also improved understanding of daytime glucose metabolism in overweight individuals without impaired glucose tolerance or overt diabetes.
The antipsychotic dopamine 2 receptor antagonist diphenylbutylpiperidines improve glycemia in experimental obesity by inhibiting succinyl-CoA:3-ketoacid CoA transferase
Authors: Dakhili Seyed Amirhossein Tabatabaei , Greenwell Amanda A. , Yang Kunyan , Farraj Rabih Abou , Saed Christina T. , Gopal Keshav , Chan Jordan S. F. , Chahade Jadin J. , Eaton Farah , Lee Crystal , Velazquez-Martinez Carlos A. , Crawford Peter A. , Glover J. N. Mark , Batran Rami Al , Ussher John R.
Published: November 2022

Despite significant progress in understanding the pathogenesis of type 2 diabetes (T2D), it remains difficult to manage. Hence, new therapeutic options targeting unique mechanisms of action are required. We have previously observed that elevated skeletal muscle succinyl CoA:3-ketoacid CoA transferase (SCOT) activity, the rate-limiting enzyme of ketone oxidation, contributes to the hyperglycemia characterizing obesity and T2D. Moreover, we identified that the typical antipsychotic agent, pimozide, is a SCOT inhibitor that can alleviate obesity-induced hyperglycemia. We have now extended those observations herein, using computer-assisted in silico modelling and in vivo pharmacology studies that highlight SCOT as a noncanonical target shared amongst the diphenylbutylpiperidine (DPBP) drug class, which includes penfluridol and fluspirilene. All 3 DPBPs tested (pimozide, penfluridol, and fluspirilene) improved glycemia in obese mice. While the canonical target of the DPBPs is the dopamine 2 receptor, studies in obese mice demonstrated that acute or chronic treatment with a structurally unrelated antipsychotic dopamine 2 receptor antagonist, lurasidone, was devoid of glucose-lowering actions. We further observed that the DPBPs improved glycemia in a SCOT-dependent manner in skeletal muscle, suggesting that this older class of antipsychotic agents may have utility in being repurposed for the treatment of T2D. 
Toward defect-free components in laser metal deposition with coaxial wire feeding through closed-loop control of the melt pool temperature
Authors: Bernauer Christian , Zapata Avelino , Zaeh Michael F.
Published: November 2022

Laser metal deposition (LMD) is an additive manufacturing process in which a metal powder or wire is added to a laser-induced molten pool. This localized deposition of material is used for the manufacturing, modification, and repair of a wide range of metal components. The use of wire as feedstock offers various advantages over the use of powder in terms of the contamination of the process environment, the material utilization rate, the ease of handling, and the material price. However, to achieve a stable process as well as defined geometrical and microstructural properties over many layers, precise knowledge on the effects of the input variables of the process on the resulting deposition characteristics is required. In this work, the melt pool temperature was used as an input parameter in LMD with coaxial wire feeding of stainless steel, which was made possible through the use of a dedicated closed-loop control system based on pyrometry. Initially, a temperature range was determined for different process conditions in which a stable deposition was obtained. Within this range, the cause-effect relationships between the melt pool temperature and the resulting geometry as well as the material properties were investigated for individual weld beads. It was found that the melt pool temperature is positively correlated with the width of the weld bead as well as the dilution. In addition, a dependence of the microhardness distribution over the cross section of a weld bead on the melt pool temperature was demonstrated, with an increased temperature negatively affecting the hardness.
Zeroing Hunger as a Public Concern: Where Rests Developing Countries Priorities?
Authors: Bernard TN Otubuah
Published: November 2022

The bout with hunger can be won by 2030 in developing countries when priorities are set right. The priorities of developing countries must be shifted from the quick fixes of hunger programs without a review to enhancing all existing local and regional food systems, coupled with an appraised local or national food defense plan, and a minimum nutritional benchmark of local diets based on a local or regional foods and nutrition data base systems. All these systems must be coordinated to yield a national food systems plan for action. To make our prize fight with hunger successful and more sustainable, these systems and plans must be reviewed and updated timely.
Pelatihan Pengembangan Media Pembelajaran Interaktif Berbasis Audio Visual Bagi Mahasiswa PGSD Universitas Lampung
Authors: Oktaria Sheren Dwi , Destiani  , Habibi Roy Kembar , Profitha Nindy , Nuraini Siti , Hermawan Jody Setya , Hariyanto
Published: November 2022

The use of audio-visual media in learning will increase students' motivation and learning outcomes. Students from the PGSD Study Program, University of Lampung as prospective educators are required to be able to innovate creatively by utilizing technological advances for learning media. One of them is using camtasia studio media. So that students are able to use Camtasia perangkat lunak, training in the development of interactive media based on Camtasia audio-visual is needed. After attending this training, PGSD students understand and use the features of Camtasia Studio. So that students are able to modify the learning media into interactive audio-visual learning media.
Pengembangan Penuntun Praktikum Biokimia Terintegrasi Nilai Islam
Authors: Idamansyah Dedy , Rohmadi Mukhlis , Ayatusa'adah Ayatusa'adah
Published: November 2022

Belum tersedianya penuntun praktikum yang terintegrasi Islam pada mata kuliah praktikum Biokimia menyebabkan mahasiswa kesulitan dalam mengintegrasikan nilai Islam pada materi yang berkaitan dengan topik praktikum Biokimia sehingga diperlukan pengembangan bahan ajar. Tujuan penelitian ini untuk mengetahui proses pengembangan penuntun praktikum melalui tahapan untuk menguji kepraktisan, dan kevalidan penuntun praktikum yang dikembangkan. Penelitian ini merupakan penelitian RD (Reseacrh and Development) menggunakan desain ADDIE. Metode penelitian menggunakan metode penelitian ini untuk menghasilkan suatu produk tertentu, dan menguji kepraktisan produk tersebut. Uji produk dilakukan dengan uji skala kecil. Instrumen penelitian menggunakan angket validitas ahli, angket respon mahasiswa, angket observasi keterlaksanaan. Hasil penelitian mendapatkan nilai validasi ahli media memperoleh persentase 82,01% dengan kriteria sangat valid, validasi ahli integrasi memperoleh persentase 83,33% dengan kriteria sangat valid dan validasi ahli materi memperoleh persentase 75,72% dengan kriteria valid. Untuk nilai kepraktisan memperoleh rata-rata 3,48 dengan persentase 87,18 memiliki kriteria sangat baik sedangkan keterlaksanaannya memperoleh persentase 81,81% dengan kriteria berhasil. Berdasarkan perolehan hasil penelitian maka produk berupa penuntun praktikum terintegrasi keislaman mata kuliah Biokimia dapat dikatakan valid dan praktis serta dapat digunakan sebagai media pembelajaran mata kuliah praktikum Biokimia.
Implementasi Media Asesmen Berbasis Gamifikasi terhadap Motivasi Belajar Biologi Siswa MAN Kotawaringin Timur
Authors: Febryana Noor Eka , Zubaidah Zubaidah
Published: November 2022

Penelitian ini bertujuan untuk mengetahui tingkat motivasi belajar peserta didik dan pengaruh implementasi media asesmen berbasis gamifikasi terhadap motivasi belajar. Jenis penelitian ini adalah penelitian kuantitatif dengan metode Pra-Eksperimental dan desain penelitian One Grup Pretest-Posttest. Sampel yang digunakan dalam penelitian ini adalah sebanyak 120 orang siswa kelas XI IPS. Instrumen yang diterapkan dalam penelitian ini meliputi angket motivasi belajar peserta didik yang diberikan sebelum dan sesudah implementasi pembelajaran. Data hasil penelitian ini dianalisis uji-t menggunakan Microsoft Office 365 yaitu pada t-Test: Two-Sample Assuming Equal Variances. Hasil penelitian ini menunjukkan bahwa sebelumnya tingkat motivasi belajar siswa hanya sebesar 55% dengan kategori rendah sebelum diterapkannya pembelajaran biologi menggunakan media asesmen berbasis gamifikasi, dan tingkat motivasi belajar siswa setelah implementasi pembelajaran berbasis asesmen gamifikasi  sebesar 74,32% dengan kategori baik. Serta diperoleh thitung (4,163931) ttabel (2,131847) sehingga dapat disimpulkan bahwa implementasi asesmen berbasis gamifikasi dalam pembelajaran biologi lintas minat memiliki pengaruh yang signifikan terhadap motivasi belajar peserta didik kelas XI IPS tahun ajaran 2021/2022.
Pengembangan Perangkat Pembelajaran Berbasis Problem Based Learning Terhadap Kemampuan Berpikir Kritis Siswa
Authors: Asminah Asminah , Ningsih Kurnia , Wahyuni Eko Sri
Published: November 2022

Penelitian ini bertujuan untuk mendeskripsikan kelayakan pengembangan perangkat pembelajaran (RPP, PPT dan LKPD) berbasis Problem Based Learning (PBL), kemampuan berpikir kritis dan respon peserta didik terhadap PPT dan LKPD pada materi virus. Metode penelitian yang digunakan adalah RD dengan tahapan potensi dan masalah, pengumpulan data, desain produk, validasi desain, revisi desain, ujicoba produk, dan revisi produk. Instrumen yang digunakan adalah lembar validasi RPP, PPT dan LKPD berbasis PBL dan angket respon peserta didik. Perangkat pembelajaran berbasis PBL yang divalidasi oleh 2 orang dosen Pendidikan Biologi FKIP Untan dan 3 orang guru Biologi SMAN 1 Sanggau Ledo dengan subjek penelitian yaitu 6 orang peserta didik. Hasil validasi perangkat pembelajaran dianalisis menggunakan metode analisis Lawshe adalah 1.00 dan melebihi batas nilai minimum yaitu 0.99 sehingga dinyatakan valid dan layak digunakan. Hasil tes evaluasi 1, tes 2 dan tes 3 diperoleh rata-rata 86%, 91.7% dan 91.8%. Dapat disimpulkan perangkat pembelajaran yang dikembangkan dapat meningkatkan kemampuan berpikir kritis peserta didik. Hasil respon peserta didik terhadap PPT dan LKPD pada ujicoba tahap awal diperoleh rata-rata 84.76% dan 87% dengan kategori positif dan sangat positif. Sehingga dapat disimpulkan bahwa kemampuan berpikir kritis peserta didik meningkat setelah diterapkan perangkat pembelajaran yang dikembangkan.
Hasil Belajar Peserta Didik dengan Penerapan Pembelajaran Kooperatif Tipe STAD pada Materi Usaha
Authors: Shiddiq Shiddiq , Septiana Nurul , Syar Nur Inayah , Annovasho Jhelang
Published: November 2022

Penelitian ini dilatar belakangi penerapan pembelajaran secara online dikarenakan masih dalam masa COVID-19 yang dilakukan di MTs Muslimat NU Palangka Raya. Tujuan dari penelitian ini yaitu medeskripsikan Hasil Belajar Peserta Didik dengan Penerapan Pembelajaran Kooperatif Tipe STAD pada Materi Usaha. Penelitian ini dilatar belakangi penerapan pembelajaran secara online dikarenakan masih dalam masa COVID-19 yang dilakukan di MTs Muslimat NU Palangka Raya. Penelitian ini menggunakan pendekatan kuantitatif deskriptif. Sampel dalam penelitian ini yaitu kelas VIII B berjumlah 12 orang peserta didik. Hasil yang diperoleh Hasil belajar peserta didik dengan penerapan pembelajaran kooperatif tipe STAD terhadap 12 orang peserta didik yang dimana 6 orang memiliki kategori tinggi, 5 orang memiliki kategori sedang, dan 1 orang memiliki kategori rendah. Rata-rata nilai tes hasil belajar peserta didik yatu 72,5.
Multidisciplinary development of Smart Jacket for elder care
Authors: Vuohijoki Tiina , Ihalainen Tiina , Merilampi Sari , Virkki Johanna
Published: November 2022

Limitations in physical and cognitive functioning are common among elderly people. Due to these limitations, activities of daily living, such as dressing, can be difficult, even with the help of another person. The limitations may also challenge using the assistive tools meant to support the independent living of elderly people. One significant assistive tool is a nurse call -button whose aim is to support the elder’s independent living and ensure the assistance of others when needed. In severe cases, using of such assistive tools is entirely prevented because of the user’s limited abilities.
The purpose of this study was to create a solution for the above-mentioned challenges with smart clothing. The objectives of this study were to design a Smart Jacket that 1) is easy to put on and 2) includes an easy-to-use nurse call button. The product development utilized design thinking through four different Smart Jacket versions, three of which were evaluated in multidisciplinary design workshops. The newly designed and created upper-body garment with assistive zippers in the sleeves can be put on when assistance is available without any movement of the user’s upper limbs.
Further, the developed passive RFID (radiofrequency identification)-based jacket with integrated nurse call -button is functional without an on-jacket energy -source and is thus maintenance free. The nurse call -button is functional more than four meters from an RFID reader antenna. Based on the initial expert evaluations, the developed Smart Jacket could operate as part of a bigger safety system, for example in an elderly care unit or domestic care, bringing a needed new alternative as merged nurse call -button and assistive cloth.
Cardiac Fibrosis: Only from Resident Cardiac Fibroblasts?
Authors: Sukhbaatar Pagmadulam , Khorloo Chingerel , Nyamsuren Bat-Erdene , Vanchin Byambasuren
Published: November 2022

No abstract in English