bluuebunny/crossref_metadata_2025 huggingface dataset:
Ovarian Follicular Dynamics, and Hormonal and Biochemical Profile in Post-Pubertal and Postpartum Jaffrabadi Buffaloes
Authors: Raval Rupesh J , Parmar Kiran H , Dhami Arjun J , Kavani Fulabhai S
Published: June 2022

Jaffrabadi buffalo is one of the heaviest buffalo breeds of the world (800 kg) and is known for poor reproductive efficiency. There is a scarcity of normal physiological data regarding reproductive parameters of Jaffrabadi buffalo. The primary objective of this study was to elucidate ovarian follicular dynamics, hormonal and biochemical profiles in 10 post-pubertal heifers (n=5 each of age 42±2 and 48±2 months) and five >90 days postpartum lactating buffaloes. Ultrasound monitoring of ovaries of animals was done at weekly interval and all follicles with diameter less than 4 mm (small follicles), 4-8 mm (medium follicles) and greater than 8 mm (large follicles) as well as CLs identified were recorded. Blood samples were also collected soon after each USG from all animals for assay of hormonal and biochemical profiles. The findings revealed that the average number of small, medium and large follicles, total number of follicles per ovary as well as diameters of largest and subordinate follicles varied greatly among periods between three groups. The size of corpus luteum ranged from 13.7 to 21.2 mm, 13.7 to 23.9 mm and 15.3 to 22.7 mm, respectively, in Group-I, II and III. In the first week of study, significantly higher (p less than 0.05) average numbers of small follicles in Group-I and III, and medium follicles and total numbers of follicles in Group-III were observed as compared to other groups. The diameter of largest follicles and subordinate follicles were non-significantly different among all groups at all periods of the study. Plasma estrogen levels were significantly higher (p less than 0.05) in Group-I as compared to Group-III and Group-II on first and second week, however, it increased significantly (p less than 0.05) in Group-II and I on fourth week of study period. Plasma insulin concentrations were significantly (p less than 0.01) lower in buffaloes (Group-III) than in heifers (Group-I and II) throughout the study period, while plasma total cholesterol and total protein levels were higher in Group-III on 3rd to 5th weeks of study. Further, there were no significant differences in the plasma FSH, LH, progesterone and blood glucose levels in animals of three groups between periods at any of the week. The ultrasonographic and endocrine profile suggested establishment of cyclicity with silent ovulation. However, the behavioural estrus was still not manifested by these post-pubertal heifers and postpartum lactating buffaloes. These results are helpful to diagnose anovulatory conditions and/or true anestrus and initiate estrus synchronization protocols for early conception in Jaffrabadi buffaloes.
Patients who refuse topical 5-fluoruoracil treatment: a qualitative analysis. (Preprint)
Authors: Singh Rohan , McCain Sarah , Grada Ayman , Feldman Steven R
Published: June 2022

BACKGROUND

Actinic keratosis (AK) is a common premalignant skin lesion and topical 5-fluorouracil (5-FU) is commonly used field-directed therapy. However, 5-FU is associated with frequent local skin reactions.

OBJECTIVE

To qualitatively assess experience in those who refuse treatment with 5-FU.

METHODS

Semi-structured interviews were conducted in 10 adult participants who had received treatment with 5-FU for AK between 1/1/2017 and 1/1/2020 and refused future treatment with 5-FU. Results were analyzed using qualitative research methods.

RESULTS

Although most participants had low concern when receiving a diagnosis of AK, most felt treatment was very important. When initiating treatment with 5-FU, most cited the recommendation by their healthcare professional as the primary motivator and initially had low concern with treatment. Most participants experienced difficulty with the physical burden of treatment, which caused lifestyle adjustments and a negative psychosocial impact. After treatment, most did not believe their HCP prepared them for treatment or were unsure. While half the participants felt 5-FU helped treat AKs, half were either unsure, due to premature discontinuation, or did not think 5-FU treated their AKs.

CONCLUSIONS

5-FU is one of the most commonly prescribed treatments for AKs. Although participants considered treatment important, most considered the side effects of 5-FU were not worth the benefits, and most experienced both a physical and psychosocial burden secondary to treatment. Moreover, participants were either unsure or were not adequately prepared for treatment. Although our study was limited by input from participants who refused future treatment with 5-FU, most stated they would still continue to seek treatment for AKs in the future, and would consider other topical treatments, especially if associated with a milder AE profile. Non-adherence to treatment is a major cause of resistant disease and is a major hurdle in the treatment of skin conditions. Inability to assess efficacy due to premature discontinuation secondary to 5-FU related AEs was a common theme in our cohort. Counseling patients on the benefits and risks of a medication, in addition to therapeutic alternatives, may increase adherence and improve outcomes.
Thermodynamic behavior of Na-majorite and knorringite-majorite garnet systems
Authors: Gaurav S. , Shankar S. , Raghav Anamika , Kumari Pratibha , Singh Manish
Published: June 2022

The behavior of thermal parameters pressure (P) and thermoelastic parameters i.e. Isothermal bulk modulus (K_T), its pressure derivative (K'T) and Thermal expansivity (α) has been analyzed for Na-majorite and knorringite-majorite systems at different compressions down to a maximum value of 0.3 for temperature ranges from 300 K to 1500 K. The pressure dependent compressibility of these garnets have been studied. The comprehensive study of thermodynamic and thermoelastic behavior at different isotherms and isobars respectively has been achieved by employing both Vinet equation of state and Anderson-Isaak equation. The study of thermal expansivity (α) using Anderson-Isaak and Stacy-Davis approach shows a similar trend of MgO system. Based on the validation of Kumar's approach, the lattice parameter of garnet system is computed using Kumar and modified Kumar's approach at high temperature and is found to be very less deviated from the value of lattice parameter at room temperature.
STUDY OF MAGNITUDE OF UTI CAUSED BY ESBL-PRODUCING ESCHERICHIA COLI AND ASSOCIATED RISK FACTORS
Authors: CHATURVEDI ADYA , GUPTA BHAVNA , CHATURVEDI ASHUTOSH , SISODIYA RASHMI , SHARMA RAJNI
Published: June 2022

Objective: Globally, urinary tract infections (UTIs) caused by Escherichia coli that produce extended-spectrum lactamase (ESBL) have become more common. Our study determined the magnitude of UTI occurring due to ESBL-producing E. coli and associated risk factors. Different methods for their phenotypic detection were also compared.
Methods: Uropathogenic E. coli isolated in significant numbers were assayed microbiologically. E. coli isolates (n=247) that were found significant in number tested for ESBL production using three different phenotypic methods: Phenotypic combined disk diffusion test (PCDDT), double-disk approximation test (DDAT), and E-test for ESBL production. An antibiotic susceptibility test was performed for different antibiotics. Various risk factors associated with UTIs were correlated with ESBL- and non-ESBL-producing E. coli.
Results: We found that diabetes mellitus type 2 was the most common risk factor for UTI caused due to ESBL-producing E. coli (25%). Pregnant females and patients having recurrent UTI showed less positivity for ESBL production. DDAT detected 32 ESBL-positive isolates and PCDDT detected 37 positive isolates. E-test was taken as the gold standard for ESBL detection which detected 49 isolates as ESBL producers. The highest sensitivity (71.2%) and specificity (75%) were shown by PCDDT.
Conclusion: According to the study conducted, it was concluded that PCDDT was the most reliable and economic method for phenotypic detection of ESBL.
MULTICOMPONENT ONE-POT SYNTHESIS OF NOVEL INDOLE ANALOGUES AS POTENT ANTIOXIDANT AGENTS
Authors: RAJESAB PARVEEN , CHAVAN PRABHAKAR W , BADIGER JAISHREE G , C HANAMSHETTY PRASHANT
Published: June 2022

Objective: The purpose of this study was to design and synthesize innovative multicomponent one-pot indole analogues that would be effective antioxidants for the body. Methods: A novel series of indolyl-pyrimidine derivatives were synthesized and characterized by spectrum analysis, and their antioxidant activity and DPPH, total antioxidant capacity, ferric reducing antioxidant power methods, and DNA cleavage activity were examined. Results: Compound 6a displayed promising free radical scavenging and total antioxidant properties. Compound 6b has demonstrated excellent ferric reducing activity, which is due to the presence of a “CH3” substitution at five position of indole. When compared to a standard DNA marker, compound 6a demonstrated the highest DNA cleavage activity at desired concentrations. Conclusion: We have synthesized novel pyrimidine analogues containing an indole moiety to investigate drug-like molecules. We have devised that a method that is simple, multicomponent, has a short reaction time, and is ecologically benign.
COMBINED EFFECT OF HORSE GRAM AND FENUGREEK SEED POWDERS IN HIGH FAT-HIGH SUCROSE DIET-INDUCED PRE-DIABETES IN RATS
Authors: R PADMAVATHI , G SOUMYA
Published: June 2022

Objective: The objective of the study was to investigate the combined effect of horse gram (HG) and fenugreek (FG) seed powders in high fat-high sucrose (HFHS) diet-induced pre-diabetes in rats.
Methods: Wistar rats (140–200 g) of either sex were randomly divided into four groups (n=6). Group 1, normal control, received normal pellet diet; Group 2, pre-diabetic control, received HFHS diet; Group 3, prophylactic group, received HFHS diet along with HG (200 mg/kg) and FG (200 mg/kg) combination; and Group 4, therapeutic group, received HFHS diet for 9 weeks followed by HG (200 mg/kg) and FG (200 mg/kg) combination for 28 days. Fasting blood glucose, lipid profiles, and OGTT were carried out on the 9th week in Group 1, Group 2, and Group 3, and at the end of the study in Group 1, Group 2, and Group 4.
Results: Treatment with HFHS diet for 9 weeks has significantly increased fasting blood glucose and lipid profiles in the pre-diabetic group when compared to the normal control group indicating induction of pre-diabetes in the pre-diabetic group. In the prophylactic group, horse gram and fenugreek are given simultaneously with HFHS has significantly decreased fasting blood glucose, lipid profiles when compared to the pre-diabetic group. In the therapeutic group, treatment was given after induction of pre-diabetes for 28 days. In the therapeutic group, there was a significant decrease in fasting blood glucose, lipid profiles compared to the pre-diabetic group.
Conclusion: HFHS diet-induced pre-diabetes or insulin resistance is an effective model to study and evaluate various new therapeutic modalities. The findings of the present study suggest that consumption of FG and HG as food supplements could reduce the risk of getting diabetes and progression of pre-diabetes to diabetes.
A STUDY ON BACTERIOLOGICAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY PATTERN OF SURGICAL SITE INFECTIONS IN A TERTIARY CARE HOSPITAL
Authors: USHARANI PURIMITLA
Published: June 2022

Objective: The present study was aimed to evaluate the prevalence, microbiological profile, and antibiograms of pathogenic microorganisms causing surgical site infections.
Methods: The present study was conducted in the Department of Microbiology, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Telangana. The study was conducted from the period of April 2020 to April 2021. Three hundred pus samples were analyzed for culture isolation and identification using standard protocols. Antibiotic susceptibility pattern of each isolate was performed by standard disc diffusion method by following The Clinical and Laboratory Standard Institute guidelines.
Results: A total of monomicrobial isolates 165 (55%) and polymicrobial isolates 13 (4.4%) were obtained from 300 pus samples and remaining 122 (40.6%) pus samples were sterile. The predominant bacteria were Staphylococcus aureus 50 (30.3%) followed by Pseudomonas aeruginosa 39 (23.6%) in monomicrobial infection and Klebsiella oxytoca + P. aeruginosa 3 (23%) in polymicrobial infection. The results of antibiogram of S. aureus which showed the highest sensitivity to antibiotics like linezolid 47 (94%) and doxycycline 42 (80%) compared to other antibiotics used for antibiotic susceptibility testing. Among the Gram-negative bacteria, the prevalent organism was Klebsiella species which showed the highest sensitivity to antibiotic meropenem 32 (86.5%).
Conclusion: The predominant bacterium isolated was S. aureus followed by P. aeruginosa in monomicrobial infection and K. oxytoca + P. aeruginosa in polymicrobial infection. Controlling the morbidity of surgical site infections is aided by meticulous surgical procedures, careful sterilization, judicious use of antibiotics, improved operating theater and ward conditions, control of malnutrition and obesity, management of infective foci, and diseases such as diabetes.
BLOOD TRANSFUSION SERVICES IN COVID: SCALING THE UNSCALABLE
Authors: CHOWDHRY MOHIT , ANKITA SHARMA  , AGRAWAL SOMA , MISHRA MANOJ
Published: June 2022

Objective: The present manuscript discusses our journey of providing safe BTS during this ongoing COVID-19 pandemic. Methods: It was a single-center, retrospective type of study conducted over a period of 1 year (January 2020–December 2020) in the department of transfusion medicine. The number of donations (replacement and voluntary) was compared during the pre-COVID months with that during the COVID outbreak. The measures included but were not limited to various aspects of staff management, environmental factors, guidelines implementation, and innovative assertions for implementing COVID-19 appropriate behavior. Gradually, provisions were also made for the collection of the COVID convalescent plasma from the recovered donors as a part of the management guidelines issue by the Indian Council of Medical Research. Results: COVID-19 pandemic has had a drastic negative impact on the blood donation but it has also highlighted the potential and the ability of the BTS to withstand such testing times. Conclusion: COVID-19 has left a profound impact on the blood transfusion services. It has highlighted the importance of having a coping strategy in place to withstand such times without compromising the health and the needs of the patients.
COMPARATIVE ANALYSIS OF BAND LIGATION TECHNIQUE VERSUS CONVENTIONAL HEMORRHOIDECTOMY FOR THE TREATMENT OF GRADE III HEMORRHOIDS
Authors: MAHNA ABHISHEK
Published: June 2022

Objectives: A comparative study between band ligation technique and conventional hemorrhoidectomy for the treatment of Grade III hemorrhoids was carried out to compare operative and post-operative variables.
Methods: This study was done on a sample size of 70 patients with Grade III hemorrhoids from 2019 to 2020 in the department of surgery of a medical college. Informed written consent was taken from the patients after explaining the benefits and side effects of both methods. The eligible patients were randomly divided into Group A (35 patients) for treatment by band ligation procedure and Group B (35 patients) who were treated by the conventional technique. The obtained data were subjected to statistical analysis by applying an unpaired t-test using SPSS 19.0 software.
Results: The difference between the two groups of the average age was comparable. The operative time and intraoperative bleeding were significantly lower in Group A than in Group B. The time to first bowel movement (hr) and average hospital stay were significantly lower in Group A than in Group B. Furthermore, the average number of analgesic doses required was significantly lower in Group A than in Group B. Furthermore, the time required for wound healing was significantly lower in Group A. The overall complications were found to be quite less in Group A than in Group B.
Conclusion: The rubber band ligation technique revealed better results in terms of operative and post-operative parameters as compared to the conventional hemorrhoidectomy.
GC-MS ANALYSIS OF THE METHANOL FRACTION OF AILANTHUS EXCELSA ROXB. FRUIT
Authors: KUMARI ARUNA , SHARMA R.A.
Published: June 2022

Objective: The objective of the study was to evaluate the phytochemical compounds present in the methanolic fruit extract of Ailanthus excelsa.
Methods: Phytochemical screening was carried out using the GC-MS instrument following the standard protocol.
Results: GC-MS studies revealed the presence of 65 compounds in fruit extract of Ailanthus excelsa. Among them, highest peak area (37.67%) was obtained for Mome Inositol (Six hydroxyl group polysaccharide) (Retention time 14.873).
Conclusion: This study identifies the presence of pharmacologically active compounds which can be constructive for the formulation of novel drugs.
A REVIEW ON MUCORMYCOSIS BLACK AND WHITE PHASE OF FUNGUS
Authors: KULKARNI SAKSHI , BHOSALE ANUJA
Published: June 2022

Mucormycosis started during COVID 19 when patients were treated with number of steroids oxygen, that further lead to increase in diabetes mellitus which was main cause of mucormycosis increase in black fungus further caused rhino-orbito-cerebral mucormycosis and angio invasive behavior of fungal hype that is from Mucoraceae family is main cause of the infection increases rapidly also damages the facial tissues vigorously uncontrolled diabetes, immunosuppressive, steroids poor glycemic control are main causes MRI is a technique that is been used for observing the growth of fungal hype from Epidermiological data its been proven that the mucormycosis is been spreading in countries such as India, Nepal, and Bangladesh rapidly its serious health concern in future.
TRAUMATIC INJURIES PRESENTING TO THE EMERGENCY DEPARTMENT IN A LEVEL-1
Authors: ALRASHIDI NASSER
Published: June 2022

Objective: Traumas are a major health concern in Saudi Arabia, and they can result in many injuries burden. Furthermore, it is one of the main causes of morbidity and mortality in the worldwide. As a result, the awareness of physicians who are the first to see trauma is critical. The study aims to determine the prevalence of traumatic injuries in emergency department.
Methods: It is a retrospective study that used the trauma registry of the King Abdulaziz Medical City, Trauma Center to analyze data from January 2015 to January 2020 on trauma patients admitted to the hospital. Demographic features, date and time of admission, type and mechanism of injury, patterns of transportation, and rates of severity were analyzed. p<0.05 was considered statistically significant.
Results: A total of 6095 patients, the majority were male (79.9%). Blunt trauma was the most prevalent type of injury (85.7%, p<0.001). A motor vehicle accident was the most prevalent mechanism of injury (37.5%). The highest proportion of trauma per age group was in the 21–30 year age group (28.7%). The mean of Injury Severity Score in the current study was found to be 10.7 and the injured patients’ Glasgow coma scale (GCS) mean was 13.4. The ICU stay average was 3.6 days while the hospital stay was 17.2 days.
Conclusion: This study revealed trauma injury patterns in a tertiary hospital in Riyadh, Saudi Arabia, demonstrating the local variation across genders, age groups, types of injury, and mechanisms of injury. These demographic data would be useful for local resourcing of the healthcare system to full impact.
Effect of Low Power Laser on Postoperative Pain in Endodontic treatment: Literature Review
Authors: Frota Diana Rodrigues Leão , Dias Sávio Martins de Araújo
Published: June 2022

Pain after endodontic treatment is common in cases where treatment is performed, due to factors such as extrusion of debris to the apical region, extravasation of irrigators and intracanal medications, amount of sessions that the element is exposed, complex anatomy that makes it difficult to clean and disinfect the channel system, among others. The use of low-power laser was positive in pain remission, with benefits from its biological effects through biostimulation that has analgesic, anti-inflammatory and healing character. The present study aimed to review the literature on the effect of low-power laser on the control of post-endodontic pain. For this, searches were performed in the following databases: Scielo, Google Scholar, Pubmed, Journal of endodontics and Journal of dental lasers where 24 articles were selected after inclusion and exclusion criteria. The articles included in the research were in the period 2000 and 2021 in three languages (Portuguese, English and Spanish). This study concludes that the literature and experiments related to this theme clearly show the occurrence of a variety of biological stimuli including analgesia in the affected area, stimulation of endorphin release and inhibition of nociceptors in pain control. As limited as studies are limited, further studies on the subject should be researched for a definitive conclusion.
Aislamiento y reintegración en poesía cristiana española del siglo XIII. Peculiaridades de Cristo y María
Authors: Vilchis Barrera Ana Elvira
Published: June 2022

En la literatura medieval es posible encontrar una actitud ambivalente ante los personajes marginales, que fluctúa entre el rechazo, por temor, y la acogida, al ser los marginados los sujetos a quienes puede dirigirse la práctica de muchas virtudes cristianas. Con base en lo anterior, en el presente artículo se propone analizar esa ambivalencia, a partir de la tensión entre individuo y colectividad, en cuanto que los individuos sufren procesos de aislamiento que tienden a resolverse con su reintegración a la comunidad. El corpus para este análisis está conformado por la producción poética de Gonzalo de Berceo y el Libro de los tres reyes de Oriente. La estructura del artículo presenta una tipología de estos procesos que considera dos factores: el primero, el carácter virtuoso o pecaminoso de los individuos marginales y de sus comunidades; el segundo, la volición u obligación que caracteriza al aislamiento de cada personaje. Con la combinación de estos factores se plantean cuatro categorías de aislamiento: a) obligatorio pecaminoso, b) voluntario pecaminoso, c) obligatorio virtuoso, y d) voluntario virtuoso. A partir de la exposición de algunas ocurrencias en el corpus, que sirven como casos modélicos de cada categoría, el artículo se dirige al análisis de dos personajes excepcionales que, pese a compartir rasgos y ser fundacionales para el planteamiento ideológico ambivalente de la marginalidad en las obras, sufren procesos que salen del paradigma propuesto: Cristo y María.
Miradas femeninas al mundo del narcotráfico desde la ficción
Authors: Morales Muñoz Brenda
Published: June 2022

Desde el inicio de la llamada “guerra contra el narcotráfico”, declarada en 2006 por el entonces presidente Felipe Calderón, la violencia se ha incrementado de manera alarmante en México. Esta situación ha impactado en la producción literaria mexicana del siglo xxi e incluso es en esta época en la que se presenta el auge de la polémica categoría de “narcoliteratura”. Se han publicado una gran cantidad de obras literarias que abordan el tema del narcotráfico, pero este trabajo se centrará en dos obras que comparten varios puntos en común a nivel estético, temático y de perspectiva y que, además, fueron escritas por mujeres que se encontraban fuera del canon literario centralizado: Orfa Alarcón (Monterrey, 1979) e Iris García Cuevas (Acapulco, 1977). Los objetivos de este trabajo son revisar la categoría de narcoliteratura y analizar las novelas Perra brava y 36 toneladas a partir de las miradas femeninas sobre la violencia derivada del tráfico de drogas, uno de los problemas más graves que enfrenta el país.
La elaboración de inferencias explicativas-elaborativas en hablantes de español: una aproximación preliminar
Authors: Cárdenas Almanza Karen Miladys
Published: June 2022

El presente trabajo tuvo como objetivos identificar qué tipos de inferencias, dentro del grupo de inferencias explicativas-elaborativas, generaban 18 hablantes de español de L1 y L2 (español como lengua materna y segunda lengua) de edades entre 20 a 23 años de tres grupos culturales diferentes (México, Colombia y China), y determinar si existían diferencias significativas entre éstos después de la lectura de textos en español sobre temas selectos de cultura de México. Los resultados obtenidos muestran que los grupos estudiados emplean diferentes tipos de inferencias, dentro de las cuales las de mayor aparición fueron las de causa directa y de modalidad; esto se debió a las temáticas expuestas, el tipo de texto y el nivel de conocimiento de los participantes. Se llevó a cabo un análisis estadístico en el que se concluyó que no existían diferencias significativas, ni asociación entre variables. Tales resultados se corroboraron con una prueba de chi-cuadrado y V-de Cramer; sin embargo, las inferencias explicativas-elaborativas valorativas tuvieron un efecto mayor comparado con el resto de las inferencias. No obstante, para reafirmar los hallazgos de este trabajo es necesario contar con una muestra mayor que permita arrojar conclusiones más sólidas.
Paz Patrimonialꓽ El ADN de México
Authors: Sánchez Juárez Martín Quintanilla
Published: June 2022

Martín Quintanilla Sánchez Juárez

Martín Quintanilla, descendiente de la sexta generación de Benito Juárez, el Benemérito de las Américas, con finalidad de crear una asociación y reivindicación del Patrimonio como revelador de nuestra historia y de nosotros mismos, es que crea El ADN de México como marca registrada y empresa mexicana.

A través de dicha empresa busca incitar a clases dirigentes comprometidas y a gobiernos futuros a invertir en el Patrimonio, reconociendo que es el motor primordial para el desarrollo nacional.
The snowflake soft coral Carijoa riisei (Cnidaria: Octocorallia) in Costa Rica
Authors: Vargas José A. , Breedy Odalisca
Published: June 2022

Introducción: Carijoa riisei (Clavulariidae) se encuentra alrededor del mundo en aguas tropicales. Es considerado como una especie invasora en algunas localidades. Un ejemplar fue colectado entre mareas en la región superior del estuario del Golfo de Nicoya, costa Pacífica de Costa Rica. La colección del Museo de Zoología de la Universidad de Costa Rica (MZUCR) incluye otros especímenes identificados como C. riisei. Objetivo: Identificar el ejemplar y elaborar una lista de registros del MZUCR. Métodos: El coral fue mantenido en agua de mar para permitir la observación de los pólipos abiertos. Las escleritas fueron estudiadas bajo el microscopio electrónico de barrido. Se preparó una lista de los registros del MZUCR. Resultados: Las morfologías de la colonia y de las escleritas son similares a las descritas para C. riisei. El MZUCR incluye 50 registros de C. riisei a lo largo de la costa del Pacífico y en la Isla del Coco. Conclusiones: Pendiente de corroboración genética, identificamos el espécimen como Carijoa riisei con base en su morfología. La mayoría de los registros del MZUCR son de hace una década o más. Una evaluación de la presencia de este coral en las costas del Pacifico y Caribe es necesario para establecer mejor su papel ecológico actual en Costa Rica.
THE APPLICATION PROBLEM BASED LEARNING APPROACH WITH PICTURE MEDIA TO EXPLANATION TEXT WRITING LEARNING FOR JUNIOR HIGHSCHOOL STUDENT
Authors: Suparna Suparna
Published: June 2022

The purpose of this study is to describe problem-based learning steps with the help of image media in the learning of explantation writing and writing results before and after the implementation of learning in control and experiment classes.The research location was conducted at SMP Negeri 1 Bungursari Purwakarta in the 2019/2020 school year.The research method used is an experimental method with the design of a kuasi experiment.The research procedure is carried out with three stages, namely the implementation of the initial test of writing explantation text, the implementation of problem based learning with the help of image media in the experimental class while in the control class of problem based learning implementation only and the final test of writing explantation.The sampling technique used is purposive sampling based on the similarity of the student's cognitive level.The selected samples are grade VIII A students as experimental classes and grade VIII.B as control classes..Data analysis is done with quantitative data analysis with the help of SPSS 20.0 and Microsoft Excel 2013 programs. The results of the study show that the implementation of problem-based learning with the help of image media in learning can be done with the following stages, namely: 1) the introduction of learning with the delivery of the objectives of writing explantation learning; 2) formation of study groups; 3) providing explantation text stimulus facilitated by teachers by providing stimulus with image media; 3) identify problems with the exoplanet text in the image; 4) group and process data to answer questions; 5) convey the results of the discussion, and 6) conclude the learning.The results of writing were obtained that the improvement of writing ability of students whose learning using problem-based learning approach with the help of image media is better than those using problem based learning approach only.This is seen from the average difference test significance value below 0.05.
LEARNING MIRROR READING USING THINK PAIR AND SHARE METHOD IN CLASS X SMA STUDENTS
Authors: Safaat Firman
Published: June 2022

Learning to read short stories using the Think, Pair, and Share methods is learning to read a short story text through the steps of learning to think, pair up, and share with class X students of Albidayah High School Academic. This study aims to determine whether there are differences in student learning outcomes by using the Think, Pair, and Share Methods in the short story reading subjects. The research method used is Quasi Experimental Design which is a development of True Experimental Design. The form of research chosen was the type of Nonequivalent Control Group Design. The population in this study were all class X students of Albidayah High School with a sample of two classes totaling 60 students. The research data were obtained using the instrument in the form of a description test given at the time of the initial test before learning began and the final test after conducting the learning process with the same type of questions. The results obtained an average of 80.6 experimental class while in the control class obtained an average of 72.8 in the final test. Based on the initial T-test calculation results obtained 0.232 while the Mann-Whitnay calculation obtained 003 results. The results of this study indicate that learning to read short stories using the Think, Pair, and Share methods is effectively applied to learning to read short stories. 6 experimental class while in the control class obtained an average of 72.8 in the final test. Based on the initial T-test calculation results obtained 0.232 while the Mann-Whitnay calculation obtained 003 results. The results of this study indicate that learning to read short stories using the Think, Pair, and Share methods is effectively applied to learning to read short stories. 6 experimental class while in the control class obtained an average of 72.8 in the final test. Based on the initial T-test calculation results obtained 0.232 while the Mann-Whitnay calculation obtained 003 results. The results of this study indicate that learning to read short stories using the Think, Pair, and Share methods is effectively applied to learning to read short stories.
IMPROVING READING ABILITY OF CLASS II STUDENTS ELEMENTARY SCHOOL TIPAR IN LEARNING LANGUAGE ABILITIES THROUGH IMAGE MEDIA
Authors: Nurhayati Tati
Published: June 2022

This study aims to explain about learning to read beginners using picture media classically and in groups and the process of increasing students' reading skills. Achieve this goal, classroom action research was conducted, with assistance of classroom teachers and 30 students of SDN TIPAR. Research data obtained by qualitative methods, observation and assisted by a recording aid in form of a camera. This research was conducted with two cycles of action. First cycle tends to increase participation and reading ability in word card and picture matching games. and the second cycle on reading improvement. Each cycle consists of stages: preparation, action, action, observation, analysis and reflection. The results of this study indicate that learning to read beginning with picture media classically students who lack courage tend to be passive so that when teacher assigns students to match word cards with pictures the students do not want to and the attention of some students is less focused in this learning and their reading ability is still dominated by active students. Learning the ability to read using picture media in groups, students are invited to play a game of matching word cards with pictures and their own friends and teacher acts as a facilitator and motivator. Student creativity, student shyness can be overcome and students' reading ability can be improved and the learning atmosphere is more attractive.
IMPROVING THE LEARNING OUTCOMES OF CLASS IV STUDENTS IN INDONESIAN LESSON ABOUT FICTION STORIES USING AUDIO VISUAL MEDIA
Authors: Fitri Ayu Nur , Nurhayati Enung
Published: June 2022

This study was conducted with the aim of knowing (1) student learning outcomes before using audio visual media in B.Indonesia subjects for grade IV students (2) student learning outcomes after using audio visual media in B.Indonesia subjects for grade IV students. This research is a quantitative descriptive study. The subjects of this study are the fourth grade students of SDN 3 Cimerang, with a total of twenty students. Data collection techniques used in this study were observation and tests. The results of the study concluded that the learning outcomes of B.Indonesia fourth grade students increased. Learning outcomes before using audio-visual media obtained learning outcomes with an average class of 69.25 the number of students who complete is 12 students or 60% and the number of students who have not completed is eight students or 40%. Whereas after using audio-visual media the learning outcomes have increased again, with an average grade of 85.5 the number of students completing is 18 people or 90% and the number of students who have not completed is two people or 10%. Based on the findings and discussion it can be concluded that learning B.Indonesia by using audio visual media can improve the understanding and learning outcomes of fourth grade students.
SARA MILLSâ€™ CRITICAL DISCOURSE ANALYSIS ON ONLINE NEWS ARTICLES ABOUT VIOLENCE CASES AGAINST WOMEN
Authors: Nurhasanah Iceu Siti , Sogiri Aos
Published: June 2022

This study focused on discussing violence among women in online media news. Good media can convey balanced information. Some news related to violence against women can be represented in a different discourse. Currently, the exploitation of women is carried out through more intellectual and well-packaged ways, one of which is through discourses published in the mass media, especially online media. Women in the mass media are positioned to stand out visually but are very marginalized in meaning. Suppose things like this continue to be left unchecked. In that case, it will emphasize the existence of gender inequality between women and men which has implications for increased violence and gender oppression with women who are always the victims. The problem discussed in this study is critical discourse analysis using the Sara Mills model. Sara Mills' discussion of feminist discourse theory is the center of her study. In addition, it also discusses women's issues, such as how women are represented in texts, pictures, photos, and in the news. This research examines how the text becomes biased in presenting women and how the marginalization of women is formed in weakening the position of women.
CERTIFICAÇÃO PECIM: A PESQUISA CIENTÍFICA COMO SUPORTE ÀS POLÍTICAS PÚBLICAS EDUCACIONAIS
Authors: Campos Junqueira Fernanda , Andrade Costa Jessica , Peres Padovani Jordana , Braga Tiago
Published: June 2022

Este capítulo é voltado para profissionais da área da Educação e a sociedade civil que se interessa pela temática. Refere-se ao Programa das Escolas Cívico-Militares (PECIM), que tem como propósito a promoção da melhoria na qualidade da educação básica, tanto no nível fundamental quanto no médio, com a redução da evasão, a diminuição da repetência e a diminuição do abandono escolar (PRESI-DÊNCIA DA REPÚBLICA, 2019). Trata-se do resultado de um trabalho coletivo entre o Ministério da Educação (MEC), o Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT), a Universidade de Brasília (UnB) e a Fundação de Desenvolvimento da Pesquisa (FUNDEP), visando a construção da metodologia de certificação do Programa. O capítulo foi realizado a partir de pesquisas, estudos e laboratórios do projeto “Desenvolvimento de metodologia de monitoramento e avaliação para a certificação das escolas participantes do Programa Nacional das Escolas Cívico-Militares – PECIM”. O principal objetivo é contribuir com a área da Educação, no que tange o processo de estruturação da pesquisa e proposição de uma metodologia de certificação para as escolas aderentes ao Programa
A EXPERIÊNCIA DA ESCOLA “PROFESSOR ÂNGELO CASCAES TANCREDO CÍVICO-MILITAR”
Authors: Luciana Medeiros Gomes Raulino Luciana Medeiros Gomes Raulino , Boaretto Pereira Paula , Raulino João Antonio , Neves Carvalho Marcelo , Borges Ednei
Published: June 2022

Apresentar os resultados verificados em sua comunidade identificando o status quo anterior à adesão, o processo de adesão, os primeiros resultados verificados na escola e quais as expectativas que se tem na continuidade da referida política.
Negative reflections of nepotism on employees and obstacles in the process of institutionalization of family businesses
Authors: Spahi Jyxhel , Shala Venet , Lima Demir
Published: June 2022

One of the most prominent problems faced by family businesses is the presence of nepotism. This study was conducted to find out if nepotism is present in local family businesses operating in Kosovo. It also aims to identify the negative reflections of nepotism on employees and the effects of nepotism on obstructing the institutionalization of family businesses. In this study, direct interviews were conducted with the managers of 10 family businesses who have no family ties with the founders of the business. The study was conducted with qualitative methods with the model of the case study, where the program MAXQDA 2020 was used for data analysis, which created codes and categories from the results of interviews. From the results of this study, it is understood that nepotism as a phenomenon is widespread in these enterprises. On the other hand, some of the negative reflections of nepotism on the managers and other employees of these family businesses have been identified as a result of the existence of nepotism. It is also understood that the existence of nepotism is an obstacle to the institutionalization of family businesses
In silico prediction of the inhibition of new molecules on 3CLpro SARS-CoV-2 enzyme by using QSAR-SVRPSO approach
Authors: Madani Achouak , Benkortbi Othmane , laidi maamar , Hamdeche Mabrouk , Hanini Saleh
Published: June 2022

Continuous effort is dedicated to the discovery of potential drugs for
the novel coronavirus-2 both clinically and computationally.
Computer-Aided Drug Design CADD is the backbone of drug discovery, and
shifting to computational approaches has become a need. Quantitative
Structure-Activity Relationship QSAR is a widely used approach in
predicting the activity of potential molecules and is an early step in
drug discovery. 3CLpro is a highly conserved enzyme in the coronaviruses
characterized by its role in the viral replication cycle. Despite the
existence of various vaccines, the development of a new drug for
SARS-CoV-2 is a necessity to provide cures to patients. In the pursuit
of exploring new potential 3CLpro SARS-CoV-2 inhibitors and contributing
to the existing literature, this work opted to build and compare three
models of QSAR to correlate between the molecules’ structure and their
activity: IC50, through the application of MLR, SVR, and SVR-PSO
algorithms. The database was selected based on its novelty and proven
activity, and its representative descriptors were obtained by the GA
algorithm. The built models were plotted and compared following various
internal and external validation criteria, and applicability domains for
each model were determined. The results demonstrated that the SVR-PSO
model performed best in terms of predictive ability and robustness,
followed by SVR, and finally MLR. These outcomes prove that the SVR-PSO
model is robust and concrete and paves the way for its prediction
abilities for future screening of larger inhibitors’ datasets.
Inner ear contrast MRI for patients with definite Meniere's disease and low- and low-to-mid-tone hearing loss
Authors: Koda Kento , Yasuhara Kazuo , Sugasawa Shunichi , Nagano Gentaro , Katoh Mitsuhiko , Kakigi Akinobu
Published: June 2022

Abstract BACKGROUND: Meniere’s disease (MD) involves cochlear and
vestibular symptoms, but the underlying cause remains unclear. Findings
predominantly show a low-to-mid-tone hearing impairment, and it is not
possible to predict hearing improvement after an attack. OBJECTIVE: To
examine whether improvement in hearing in definite MD (DMD) patients
could be predicted using inner ear contrast magnetic resonance imaging
(IEC-MRI) and pure tone audiometry (PTA) at the time of an attack.
METHODS: Between April 2020 and March 2022, seven DMD outpatients were
enrolled based on the Bárány Society DMD criteria. Patients were divided
into two groups: a low-tone hearing loss (LTL) group and a
low-to-mid-tone hearing loss (LMTL) group. Hearing improvement rates
were examined. We also examined whether endolymphatic hydrops and
hearing improvement were related. RESULTS: Endolymphatic hydrops was
found in two of four LTL cases. One of three LMTL cases had prominent
lymphedema. All LTL patients showed hearing improvements. Only one LMTL
patient showed hearing improvement. Endolymphatic hydrops did not
correlate with hearing improvement. CONCLUSIONS: It is not possible to
estimate hearing improvement using IEC-MRI. PTA showed that LTL had a
better hearing prognosis than LMTL. Therefore, it is possible to
estimate hearing improvement using PTA.
Acute Liver Failure Due to Acute Hepatitis B Infection-Potential of Zoonotic Transmission
Authors: Kandel Pujan , McDonald Philip , Bachuwa Ghassan
Published: June 2022

There is no definitive animal HBV reservoir for transmission to humans.
We reported a case of 48-year-old male with acute liver failure due to
acute hepatitis B infection and considered the possibility of
concomitant zoonotic hepatitis E (HEV) infection to explain the severity
of his presentation.
Invited commentary: Total anomalous pulmonary venous connection remains a challenging pediatric disease
Authors: Do-Nguyen Chi Chi , Throckmorton Amy , Stevens Randy
Published: June 2022

Cervantes-Salazar and colleagues report the long-term surgical outcomes
of 414 patients with total anomalous pulmonary venous connection (TAPVC)
from January 2003 to June 2019. With an overall survival rate of 87.2%
from 2003 to 2019, the authors found that an increased mortality risk
was associated with infra-cardiac TAPVC, pulmonary venous obstruction
(PVO), and postoperative mechanical ventilation. Their comprehensive
study with a large sample size of varying age groups, and patients with
late referrals for surgery, provide valuable insight into TAPVC surgical
outcomes. Improved survival for these patients continues to be a major
goal of clinical teams striving to transform treatment paradigms. The
comprehensive and promising results of the study reported by
Cervantes-Salazar and colleagues gives our field hope for a better
future for these patients.
A combination of hydro-debridement with pulsed lavage and negative pressure wound therapies may enhance outcomes
Authors: Morisaki Akimasa
Published: June 2022

Deep sternal wound infection (DSWI) with prosthetic graft infection is a
rare, though lethal, complication after cardiovascular surgery via
median sternotomy. This commentary is a review of a report by Takagi et
al. published in the Journal of Cardiac Surgery that reported favorable
outcomes in patients with DWSI with prosthetic graft infection treated
with an enhanced strategy consisting of hydro-debridement with pulsed
lavage and negative pressure wound therapies.
Cryptogenic Stroke in an Adult Sudanese Female with Interatrial Septal Aneurysm: A Case Report
Authors: Daoud Mahmoud Hussien Salih , Abushama Ejlal Ahmed.E. , Mahmmoud Abdallah H. , Eljack Moh. Mah. Fadelallah , Ahmed Khabab Abbasher Hussien Mohamed , Haroun Mazin S. Hassan , Hasabo Elfatih A. , Elsheikh Duaa Baderaldeen Ibraheem , Mohammed Sulieman Abdelkareim G. , Eltayeb Ahmed Eltayeb O. , Naimallah Yusif Abduelmagid M. , Ahmed Alameen Ahmed Alameen , Yusif Mohamed Yusif Mohamed , Mokhtar Asmaa Esam Abbas , Awadalbari Sara Nasreldeen Ibrahim , Eltayeb Rowida Babikir Osman
Published: June 2022

An atrial septal aneurysm (ASA) is saccular defect of the atrial septum,
and it may be associated with congenital heart disease. Cryptogenic
strokes are strokes of unknown origins, and ASA may be one of these
causes. In this case report, we described a cryptogenic stroke in an
adult Sudanese female with interatrial septal aneurysm.
Impact of Inventory Management Flexibility on Service Flexibility and Performance: Evidence from Mainland Chinese Firms
Authors: SONG HUA , SONG YUAN-FANG
Published: June 2022

This article summarizes the literature on inventory management flexibility from a competence perspective, and it classifies the work according to inter-firm and intra-firm flexibilities. It also explores the relationships between inventory competence flexibility, service capabilities flexibility, and performance. The results show that intra-firm inventory management flexibility, which reflects internal competence, has a positive impact on service capabilities and performance, while inventory coordination flexibility, which captures inter-firm competence, has no significance on those elements. Empirical results suggest that collaborative inventory management flexibility is an important issue for Mainland China to address in the future, although intra-firm competences there have been improved.
Value Propositions of the U.S. Trucking Industry
Authors: RANDALL WESLEY S. , DEFEE C. CLIFFORD , BRADY STEPHAN P.
Published: June 2022

This article uses a method combining analysis of Web site content with the constant comparison process from grounded theory to investigate the value propositions offered by 100 U.S. motor carriers. Using the selling messages of the Web site for these firms, coupled with follow-up interviews, we found that the basic motor carrier value proposition is developed around the four themes of time, place, value management, and value-add. In addition we found underlying capabilities (e.g., type equipment, technology, reliability) that carriers suggest are required to create those value proposition themes. These messages serve an important role in differentiating a firm's offering in a commodity business, like the U.S. motor carrier industry, where price is not a distinguishing factor in most cases. Our findings suggest that many of the sampled firms attempt to avoid price-based commoditization through the value propositions they project.