bluuebunny/crossref_metadata_2025 huggingface dataset:
Межкультурно-коммуникативное обучение иностранным языкам
Authors: Gallo Jan
Published: November 2018

This paper discusses the issue of cross-cultural foreign language teaching accentuating Russian Foreign Language Teaching at colleges in Slovakia. In the introduction some ideas on the position and meaning of cross-cultural communication are presented. In the second part there are explanations of the term cross-cultural communication by some linguists and methodists, as well as its implementation on several levels. In the third part attention is focused on the relations between cross-cultural communication and foreign language teaching. The issue of cross-cultural (policultural) didactics is also explained. In the fourth part the problem of cross-cultural teaching methodology is discussed. In the fifth part the focus is on presenting a summary of cross-cultural communication teaching practice in the Department of Russian Studies at Constantine the Philosopher University in Nitra. The paper concludes with a summary of the problems investigated.
Evaluation of analytical performances using standardized analytical protocols and comparison of clinical results of the new ADVIA BNP and NT-proBNP immunoassays for the Centaur XPT platform
Authors: Masotti Silvia , Musetti Veronica , Prontera Concetta , Storti Simona , Ndreu Rudina , Passino Claudio , Zucchelli Giancarlo , Clerico Aldo
Published: November 2018

Background

The study aim was to evaluate and compare analytical performances and clinical results of ADVIA BNP and PBNP methods using the Centaur XPT platform with those of Access BNP, using the DxI platform and the ECLIA NT-proBNP method, using the Cobas e411 platform, respectively.

Methods

Limits of blank (LoB), detection (LoD) and quantitation (LoQ) at 20% CV and 10% CV were evaluated according to international standardized protocols. The analytical parameters were assessed throughout a 90-working-day period using three curve calibrations.

Results

LoB, LoD and LoQ at 20% CV and 10% values of the ADVIA BNP method were 1.0 ng/L, 2.0 ng/L, 3.7 ng/L and 10.2 ng/L, respectively; while those of the ADVIA PBNP method were 1.3 ng/L, 3.0 ng/L, 9.7 ng/L and 22.3 ng/L, respectively. The ADVIA BNP and PBNP methods were able to measure the clinical decision values suggested by international guidelines for diagnosis of heart failure (HF) with an imprecision ≤6%. BNP concentrations measured with the ADVIA and Access methods showed a close linear regression (R=0.9923, n=200); a close linear regression was also found between NT-proBNP concentrations measured with the ADVIA and ECLIA methods (R=0.9954, n=202). However, the ADVIA method measured significantly lower BNP values than the Access method (on average −20.9%), while ADVIA PBNP method measured significantly higher NT-proBNP concentrations than the ECLIA method (on average +17.8%).

Conclusions

Analytical performances of the BNP and PBNP ADVIA methods are well in accordance with the quality specifications required by international guidelines for diagnosis and follow-up of patients with HF.
Macro-CK type 2 in metastatic prostate cancer
Authors: Eidizadeh Abass , von Ahsen Nicolas , Friedewald Steffen , Binder Lutz
Published: November 2018

The isoenzyme creatine kinase muscle/brain (CK-MB) still plays an important role for the differential diagnosis of CK elevations and the clarification of their origin from heart or skeletal muscle. Therefore, it is necessary to know the diagnostic pitfalls in interpreting CK-MB results. We demonstrate a case of macro-CK type 2 in a 75-year-old patient with metastatic castration-resistant prostate cancer and its identification by isoenzyme electrophoresis, which can be typical for cancer diseases.
Crystal structure of oxidobis(piperidine-1-carbodithioato-κ2
S,S′)vanadium(IV), C12H20N2OS4V
Authors: Machálková Aneta , Charamzová Iva , Honzíček Jan , Vinklárek Jaromír , Císařová Ivana
Published: November 2018

C12H20N2OS4V, triclinic, P1̄ (no. 2), a = 7.0892(2) Å, b = 8.8797(2) Å, c = 13.8486(3) Å, α = 87.1010(10)°, β = 82.3160(10)°, γ = 71.4110(10)°, V = 818.84(3) Å3, Z = 2, R
gt(F) = 0.0249, wR
ref(F
2) = 0.0707, T = 150(2) K.
The crystal structure of trans-dichlorido-bis(pyridine-2-carboxylato-κ2
N,O)platinum(IV), C12H8Cl2N2O4Pt
Authors: Ha Kwang
Published: November 2018

C12H8Cl2N2O4Pt, triclinic, P1̄ (no. 2), a = 6.6940(3) Å, b = 9.5552(6) Å, c = 10.7954(6) Å, α = 83.8311(19)°, β = 88.1577(16)°, γ = 86.8053(17)°, V = 685.20(7) Å3, Z = 2, R
gt(F) = 0.0244, wR
ref(F
2) = 0.0601, T = 223(2) K.
The crystal structure of N,N′-(6-(thiophen-2-yl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropane-2-sulfonamide) – ethyl acetate(2/1), C34H54N10O6S6
Authors: Zuo Zhenyu , Yan Hao , Song Xiao , Song XiaoMei , Guo Dongyan
Published: November 2018

C34H54N10O6S6, monoclinic, P21 (no. 4), a = 11.8434(5) Å, b = 11.2298(6) Å, c = 17.0706(8) Å, β = 94.661(2)°, V = 2262.86(19) Å3, Z = 4, R
gt(F) = 0.0287, wR
ref(F
2) = 0.0809, T = 150(2) K.
New light on neurotransmitter-gated receptors: Optical approaches for controlling physiological function
Authors: Reiner Andreas
Published: November 2018

Neurotransmitter-gated receptors contribute to synaptic transmission and modulation in many ways. Considering glutamate receptors as an example, it becomes clear that these receptor families are highly diverse and that it is experimentally challenging to disentangle the different functional contributions of closely related receptor subtypes. Pharmacological and genetic methods are now complemented by optogenetic approaches, which allow for controlling receptor signaling with light. Using glutamate receptors as an example, I summarize how tethered photoswitchable ligands can be used to control individual receptor subtypes with high spatial and temporal precision, and in specific cells. These, and similarly exciting approaches, offer new possibilities for probing the function of individual receptors in the nervous system.
See what you hear – How the brain forms representations across the senses
Authors: Noppeney Uta , Jones Samuel A. , Rohe Tim , Ferrari Ambra
Published: November 2018

Abstarct

Our senses are constantly bombarded with a myriad of signals. To make sense of this cacophony, the brain needs to integrate signals emanating from a common source, but segregate signals originating from the different sources. Thus, multisensory perception relies critically on inferring the world’s causal structure (i. e. one common vs. multiple independent sources). Behavioural research has shown that the brain arbitrates between sensory integration and segregation consistent with the principles of Bayesian Causal Inference. At the neural level, recent functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) studies have shown that the brain accomplishes Bayesian Causal Inference by dynamically encoding multiple perceptual estimates across the sensory processing hierarchies. Only at the top of the hierarchy in anterior parietal cortices did the brain form perceptual estimates that take into account the observer’s uncertainty about the world’s causal structure consistent with Bayesian Causal Inference.
The Transfer Characteristics of Hair Cells Encoding Mechanical Stimuli in the Lateral Line of Zebrafish
Authors: Pichler Paul , Lagnado Leon
Published: November 2018

Hair cells transmit mechanical information by converting deflection of the hair bundle into synaptic release of glutamate. We have investigated this process in the lateral line of larval zebrafish (male and female) to understand how stimuli are encoded within a neuromast. Using multiphoton microscopyin vivo, we imaged synaptic release of glutamate using the reporter iGluSnFR as well as deflections of the cupula. We found that the neuromast is composed of a functionally diverse population of hair cells. Half the hair cells signaled cupula motion in both directions from rest, either by increasing glutamate release in response to a deflection in the positive direction or by reducing release in the negative direction. The relationship between cupula deflection and glutamate release demonstrated maximum sensitivity at displacements of just ∼40 nm in the positive direction. The remaining hair cells only signaled motion in one direction and were less sensitive, extending the operating range of the neuromast beyond 1 μm. Adaptation of the synaptic output was also heterogeneous, with some hair cells generating sustained glutamate release in response to a steady deflection of the cupula and others generating transient outputs. Finally, a distinct signal encoded a return of the cupula to rest: a large and transient burst of glutamate release from hair cells unresponsive to the initial stimulus. A population of hair cells with these different sensitivities, operating ranges, and adaptive properties will allow the neuromast to encode weak stimuli while maintaining the dynamic range to signal the amplitude and duration of stronger deflections.

SIGNIFICANCE STATEMENTHair cells transmit information about mechanical stimuli by converting very small deflections of their hair bundle into changes in the release of the neurotransmitter glutamate. We have measured this input/output relation in the live fish using a fluorescent protein and find that different hair cells vary in their mechanical sensitivity and the time course of their response. These variations will allow the fish to sense the timing and duration of both very weak stimuli (∼40 nm deflections) and strong stimuli (∼1 μm), underlying the ability of the fish to avoid predators and maintain its body position in flowing water.
Heterochromatin-Enriched Assemblies Reveal the Sequence and Organization of theDrosophila melanogasterY Chromosome
Authors: Chang Ching-Ho , Larracuente Amanda M
Published: November 2018

Heterochromatic repeat-rich regions are often missing from even the best genome assemblies. Chang and Larracuente designed a de novo assembly strategy to improve the Drosophila melanogaster assembly in heterochromatin, extending the reference assembly by 11.9 Mb, including 10.6 Mb from the Y chromosome.....

Heterochromatic regions of the genome are repeat-rich and poor in protein coding genes, and are therefore underrepresented in even the best genome assemblies. One of the most difficult regions of the genome to assemble are sex-limited chromosomes. The Drosophila melanogaster Y chromosome is entirely heterochromatic, yet has wide-ranging effects on male fertility, fitness, and genome-wide gene expression. The genetic basis of this phenotypic variation is difficult to study, in part because we do not know the detailed organization of the Y chromosome. To study Y chromosome organization in D. melanogaster, we develop an assembly strategy involving the in silico enrichment of heterochromatic long single-molecule reads and use these reads to create targeted de novo assemblies of heterochromatic sequences. We assigned contigs to the Y chromosome using Illumina reads to identify male-specific sequences. Our pipeline extends the D. melanogaster reference genome by 11.9 Mb, closes 43.8% of the gaps, and improves overall contiguity. The addition of 10.6 MB of Y-linked sequence permitted us to study the organization of repeats and genes along the Y chromosome. We detected a high rate of duplication to the pericentric regions of the Y chromosome from other regions in the genome. Most of these duplicated genes exist in multiple copies. We detail the evolutionary history of one sex-linked gene family, crystal-Stellate. While the Y chromosome does not undergo crossing over, we observed high gene conversion rates within and between members of the crystal-Stellate gene family, Su(Ste), and PCKR, compared to genome-wide estimates. Our results suggest that gene conversion and gene duplication play an important role in the evolution of Y-linked genes.
Heterosis for ether extract production and its components in seed of Cucurbita argyrosperma
Authors: Valdes Restrepo Magda Piedad , Ortiz Grisales Sanin , Vallejo Cabrera Franco Alirio
Published: November 2018

Twenty-one genotypes (six parental lines and 15 direct crosses) of butternut squash (Curcurbita argyrosperma subsp. sororia) were evaluated at the Experimental Center of the Universidad Nacional de Colombia in Candelaria (Valle del Cauca, Colombia) during the second semesters of 2012 (2012B) and the first semester of 2013 (2013A). Heterotic effects (average, variety, and specific) were determined for ether extract production per plant (EEPP) and the following components: percentage ether extract (EE) in seed, seed weight per fruit (SWF), 100-seed weight (100- SW), and number of fruits per plant (NFP). The methodology of Gardner and Eberhart (1966) was used in a randomized complete block experiment design with four replicates (five plants per replicate). Variety heterosis accounted for 48% of the variation of total heterosis for EEPP. Variety heterosis was better expressed in 2013 first semester, with significant differences for EEPP, SWF, and 100-SW; average heterosis was significant for EEPP and EE. In 2012 second semester, heterosis was significant for SWF, indicating genetic divergence between hybrids and parents. Introductions 256 and 132 expressed the greatest effects of variety heterosis for EEPP and superior segregants should be selected from these two parental lines. No significant differences were observed on specific heterosis; however, the best hybrid in terms of EEPP at 2013 first semester came from crosses 256×132 and 140×260.
Effect of deficit irrigation on yield and quality of pear (Pyrus communis cv. Triumph of Vienna)
Authors: Moreno-Hernández Adriana Carolina , Vélez-Sánchez Javier Enrique , Intrigliolo Diego Sebastiano
Published: November 2018

Crop demands for irrigation require different technologies to optimize the use of water. Regulated Deficit Irrigation (RDI) is a strategy that enables a significant reduction of water application without affecting the crop yield and quality, with the advantage of being a tool for control of vegetative growth. The present study was conducted in Sesquile, Cundinamarca (Colombia) between 2015 and 2016. The objective was to evaluate the quality and development of pear crop (Pyrus communis L. cv. Triumph of Vienna) on field conditions, using three treatments of 100%, and 25% of water requirement (ETc) and no irrigation, applied at the rapid fruit growth stage. The mid day stem water potential, plant water relations, pressure-volume curve, fruit yield and quality were evaluated. There were no significant differences in the yield and quality of the fruits among the different irrigation treatments. The trees had the mechanisms of osmotic adjustment, which allowed water stressed trees to cope with irrigation restrictions during the rapid fruit growth stage without affecting the yield.
Evaluation of four degree-day estimation methods in eight Colombian coffee-growing areas
Authors: Unigarro Carlos Andres , Bermudez Florez Leidy Natalia , Medina Rubén Darío , Jaramillo Alvaro , Flórez Claudia Patricia
Published: November 2018

Methods to estimate the accumulation of degree-days based on maximum and minimum temperaturesare are commonly used to determine relationships or to adjust phenological models based on the "physiological time". Degree-days are obtained indirectly by these methods, this information is not generally available on hourly or shorter time scales due to the type of equipment used to record data or a data loss in historical time series. To compare the performance of such methods, degree-days were estimated with four indirect methods in eight Colombian locations during 1 year. Each indirect method was evaluated in comparison to the numerical integration method by the trapezoidal rule (reference method) using temperatures recorded every 5 min. Based on the percent bias error, the methods proposed by Arnold, Ometto and Snyder tend to overestimate thermal time, whereas the Villa-Nova method underestimates this time, but with a lower performance as regards to the previous ones.
The first country record of the Mexican Blind Snake, Anomalepis mexicanus Jan, 1860 (Serpentes, Anomalepididae), in Colombia
Authors: González-Carvajal Juliett M. , Medina-Rangel Guido Fabian , Rojas-Murcia Luis Eduardo
Published: November 2018

We report the first Colombian record of the Blind Snake Anomalepis mexicanus Jan, 1860, based on a single specimen from Cantagallo municipality, department of Bolívar. Our new record fills a large gap and extends this species’ geographical distribution by approximately 630 km in a straight line east-southeast from its nearest previously known Panamanian locality, and approximately 1295 km in a straight-line north-northeast from its nearest previously known Peruvian locality.
Evaluating Graduate Medical Education on Opioid Use Disorder in America’s Heroin Overdose Capital
Authors: Squibb Anna
Published: November 2018

This article was migrated. The article was not marked as recommended. BackgroundDue to the safety net nature of graduate medical education programs, resident physicians are the care providers for patients with addiction. The opioid epidemic has escalated and multiple studies have demonstrated a need to improve graduate medical education. We sought to understand the current training for opioid use disorder across all specialties of Graduate Medical Education to better understand the needs of our programs as a whole.ObjectiveThis is a cross-sectional, descriptive survey study to clarify current educational impact for our residents on opioid use disorder, current faculty experience in teaching and the plans of residents to meet community need by prescribing medication assisted therapy.MethodsForty-one residents and faculty participated in a cross-sectional, descriptive design regarding opioid use disorder education and knowledge. The survey developed utilized the Wakeman survey and was adjusted to include 2 further areas: faculty comfort in teaching skills related to opioid use disorder and resident intent to prescribe buprenorphine.ResultsThe overall response rate for the survey was 29% (41/ 139) for possible resident and faculty associated with the Kettering Network residency programs. Residents were most comfortable with diagnosis and SBIRT and this aligned with faculty comfort in teaching. Residents and faculty both demonstrated areas of opportunity in MAT, harm reduction and naloxone prescribing. Despite the areas of learning opportunities, 70% of the resident respondents intend to provide medication assisted therapy in their future practices.ConclusionsWe uncovered inconsistencies in our training and significant gaps in faculty development. We recognize a need to engage both faculty and residents in further modalities of education and faculty development.
Early-age behaviour and cracking potential of fly ash concrete under restrained condition
Authors: Shen Dejian , Wang Wenting , Li Qiyao , Yao Panpan , Jiang Guoqing
Published: November 2018

High-performance concrete (HPC) has been used extensively due to its good workability, lasting durability and high strength. However, the low water/cement ratio in HPC generally induces rather high autogenous shrinkage, resulting in high early-age cracking potential. Fly ash (FA) is an effective mineral admixture used to strengthen early-age concrete performance and lower the cracking potential. Although the early mechanical properties of concrete containing FA have been studied, literature on the cracking potential of FA HPC under adiabatic conditions and constant uniaxial restraint is limited. The influence of FA as a partial replacement of cement on the temperature, autogenous shrinkage, restrained stress, tensile creep and cracking potential of HPC was simultaneously investigated in this study. Three groups of large prismatic specimens with different FA replacement ratios (0, 20 and 50%) were tested using a temperature–stress test machine under adiabatic conditions at full restraint. The test results indicated that: autogenous shrinkage, cracking stress and restrained tensile stress rate of the HPC decreased with an increase in FA content; the use of FA as partial replacement of cement increased the ratio of cracking stress to axial tensile strength and the cracking age of the HPC; the specific tensile creep of mixtures with 20% (FA20) and 50% (FA50) replacement with FA was 0·96 and 1·16 times that of the mixture with 0% replacement (FA00), respectively; the integrated criterion used to evaluate the cracking potential decreased with an increase in FA content.
Repercussões para a família que acompanha um paciente em cuidados paliativos
Authors: Faro Carolina Lomanto , Castro Maria Luiza Sarno
Published: November 2018

Os cuidados paliativos surgem como uma mudança de paradigma na assistência ao paciente que se encontra fora de possibilidades terapêuticas, a fim de aliviar a dor e o sofrimento desse indivíduo. O presente artigo tem como objetivo compreender o que a literatura traz sobre os principais impactos que repercutem na família que acompanha um paciente diante da impossibilidade terapêutica, relatando os sentimentos e os processos vivenciados por esse núcleo, considerando as publicações brasileiras que existem sobre esse assunto. O estudo trata-se de uma revisão sistemática realizada a partir de artigos já existentes nas bases de dados  da Biblioteca Virtual de Saúde – Scielo, Lilacs e Pepsic,. O período selecionado dos artigos contemplou os anos de 2012 a 2016 e aborda os descritores: cuidados paliativos e família. Foram analisadas 15 publicações existentes e identificadas as categorias: as singularidades do cuidar no domicílio/ hospital, sentimento e sensações vivenciados pelo cuidador, dificuldades inerentes ao cuidar e fontes de apoio do cuidador. Tais categorias possibilitaram compreender que quando um dos membros do núcleo familiar depara-se com um doença fora de possibilidades terapêuticas é necessário um rearranjo nesse sistema. Além disso, diante da terminalidade, muitas vezes, um cuidador se torna responsável pelo paciente, sofrendo os impactos inerentes ao cuidar, contribuindo assim para o debate acerca dos cuidados paliativos e a atenção dada ao familiar que assume a função de cuidador.
NS-Forest version 2 v1
Authors: Aevermann Brian , Scheuermann Richard
Published: November 2018

NS-Forest is an alogrithm that determines the minimum set of genes that are necessary and sufficient to define a cell type cluster derived from single cell RNAseq expression data. Development and stable releases can be found at : https://github.com/JCVenterInstitute/NSForest
Consulta anestésica para ECT do ICS v1
Authors: Magalhães Nunes Guimarães Gabriel
Published: November 2018

Este é um guia de como deverá ser a consulta anestésica para eletroconvulsoterapia. Nossa equipe exige um padrão mínimo de qualidade destas consultas, que devem incluir informações específicas e muito relevantes para a realização de anestesias com o máximo de segurança no nosso instituto. Este guia se aplica para consultas por membros internos e externos à equipe de anestesiologia que atua no ICS-Brasília. Caso uma consulta por profissional externo não contenha os critérios mínimos de qualidade, não será considerada como passo realizado para realização de ECT com nossa equipe.
Magnetically levitated train’s longitudinal motion (Simulation results)
Authors: Polyakov Vladislav A. , Khachapuridze Nikolai M.
Published: November 2018

Background: The no-stationary regimes of the magnetically levitated train’s (MLT) motion were the object of research.
Aim: The purpose of the study is to evaluate its dynamic qualities and loading in such regimes.
Methods: The work was carried out by conducting a series of experiments with a computer model of train’s dynamics.
Results: The simulation results reflect its motion in the modes of acceleration, passage of the tunnel, as well as service and emergency braking.
Conclusion: An analysis of these results made it possible to evaluate the dynamic properties of a train in various non-stationary motion modes and its loading in their process.
Jurisprudência sobre a extensão do escopo da Lei Maria da Penha a homens heteroafetivos vítimas de violência doméstica e familiar: análise pragmático-cognitiva / Jurisprudence about the extension of the scope of Maria da Penha Law to heterosexual men as victims of domestic and family violence: cognitive-pragmatic analysis
Authors: Rauen Fábio José , Rauen Bárbara Mendes
Published: November 2018

Resumo: Analisamos neste artigo jurisprudências sobre a extensão do escopo da Lei Maria da Penha a homens heteroafetivos vítimas de violência doméstica e familiar. Para dar conta desse objetivo, aplicamos o aparato descritivo e explanatório da teoria de conciliação de metas e da teoria da relevância em cinco acórdãos sobre conflitos de competência selecionados dos tribunais de justiça da região sul do Brasil a partir de 2010. Os resultados sugerem haver uma interpretação categórica segundo a qual a Lei Maria da Penha deve ser aplicada somente em casos onde o sujeito passivo de violência doméstica e familiar é mulher (sexo), de modo que os respectivos processos não devem ser julgados por tribunais especiais.Palavras-chave: pragmática cognitiva; teoria de conciliação de metas; teoria da relevância; Lei Maria da Penha; jurisprudência.Abstract: We analyze in this article the jurisprudence about the extension of the scope of the Law 11.340/06—Maria da Penha Law—to encompass heterosexual men as victims of domestic and family violence. We apply the goal-conciliation and relevance-theoretic descriptive and explanatory apparatus on five selected cases of jurisdiction conflicts from the courts of justice of the southern region of Brazil since 2010. The results suggest a categorical interpretation according to which the Law should be applied only in cases where the passive subject of domestic and family violence is female (sex), in such a way the cases should not be judged in special courts.Keywords: cognitive pragmatics; goal-conciliation theory; relevance theory; Maria da Penha law; jurisprudence.
Sistemas de discurso e eficácia na comunicação em contextos de promoção da saúde: contribuições da técnica do detalhamento acadêmico / Discourse Systems and Efficiency in Communication in Health Promoting Contexts: The Academic Detailing Technique’s Contributions
Authors: Gedrat Dóris Cristina , Alves Gehysa Guimarães
Published: November 2018

Resumo: Considerando-se a comunicação como um processo intercultural, o objetivo deste artigo é mostrar a presença da comunicação interdiscursiva nas interações sociais e profissionais, destacando o detalhamento acadêmico como técnica que visa à aproximação do sistema de discurso da área de comércio e vendas de medicamentos com o sistema de discurso médico. Buscou-se fundamento na análise do discurso etnometodológica, com foco na comunicação entre profissionais da saúde, considerando-se esta essencialmente intercultural. Conclui-se que o detalhamento acadêmico contribui para melhorar o uso racional de medicamentos e otimizar a eficiência de sistemas de saúde porque promove uma interação entre sistemas de discursos diferentes, que têm objetivos e focos diferentes, almejando chegar ao melhor resultado possível considerando os usuários do sistema.Palavras-chave: sistemas de discurso; detalhamento acadêmico; promoção da saúde; interdisciplinaridade.Abstract: Taking communication as an intercultural process, the purpose of this essay is to show how interdiscourse communication is present in social and professional interactions, highlighting academic detailing as a technique that aims at bringing together the drug market and the medical discourse systems. The scientific basis is found in ethnomethodological discourse analysis, focusing communication among health professionals, viewed as essentially intercultural. The main conclusion is that academic detailing contributes to improve rational use of medications and to enhance efficiency in health systems because it promotes an interaction among different discourse systems, which have different aims and foci. It aims at the best possible results considering the system’s users.Keywords: discourse systems; academic detailing; health promotion; interdisciplinarity.
Análise do Discurso no blog RadFem: ser mulher para além do corpo / RadFem blog’ Discourse Analysis: Being a Woman Beyond the Body
Authors: De Tilio Rafael , Del Nero Paola Marques
Published: November 2018

Resumo: Sendo a internet um campo de disputas, há também, nesse sentido, espaço para os movimentos sociais. A popularização da internet permitiu a consolidação de redes de contatos que se constituíram como organizações políticas e grupos feministas. Valer-se das mídias sociovirtuais para fazer feminismo é, potencialmente, aproximar mais pessoas das discussões. Nos campos teórico e político, ao problematizar a categoria mulher (ou mulheres), perguntando quem são as mulheres, as feministas têm enfrentado o debate contemporâneo sobre identidade (e sujeito) de diferentes maneiras, sendo variadas, também, as posições teóricas e políticas. Sendo assim, o objetivo dessa pesquisa foi compreender os efeitos de sentidos produzidos sobre a categoria mulher e suas interlocuções no blog RadFem (feminismo radical), a partir da Análise do Discurso (AD) de Michel Pêcheux. Perante o que foi exposto na análise, faz-se possível elencar alguns efeitos de sentidos presentes no blog RadFem sustentados em discursos pautados em concepções binárias de perspectiva biológica e opressoras para caracterizar o que se entende por mulher. Assim, ressalta-se que a AD mostra-se como uma possibilidade de interpretação para a abordagem dos temas que relacionem sexualidade, gênero e Psicologia Social.Palavras-chave: análise do discurso; feminismo radical; blog; mulher.Abstract: Word Wide Web is a field of disputes and a space for social movements. The popularization of the internet allowed the consolidation of networks that constituted themselves as political organizations, alike the feminist groups. Feminism by virtual sexual networks (as internet) potentially bringing people closer to the discussions. In the theoretical and political fields, by questioning the category of woman (or women) – asking who are women feminists have faced the contemporary debate on identity (and subject) in different ways, and theoretical and political positions have also varied. The objective of this research was to understand the effects of senses produced (discourses) on the woman category and their interlocutions in a blog post RadFem (radical feminism), from Michel Pêcheux’s Discourse Analysis (AD). It is possible to list some effects of senses present in the blog RadFem sustained in discourses: based on binary conceptions of biological perspective and oppressors to characterize what is meant by woman. Thus, it is emphasized that the AD is shown as a possibility of interpretation approach to sexuality, gender and Social Psychology.Keywords: discourse analysis; radical feminism; blog; woman.
A Study on Effects of Salinity on Growth and Yield of Tomato Genotype (Solanum lycopersicum)
Authors: Umar Ja'afar , Aliyu Adamu , Shehu Kasimu , Abubakar Lawali
Published: November 2018

Saline water occupies 71% of the Earth area. It is thought that even a quarter of the whole pedosphere is affected by salts amounting to 950 x 106 ha while 23 % of the 1.5 x 109 ha cultivated land is considered as saline. This study was carried out to investigate the influence of salinity on the on growth and yield of tomato genotypes. The seedlings 20 genotype were divided into three groups, Sodium chloride (NaCl) dissolved in irrigation water to make variant concentration of 30, 60 mg/L of salt concentration using E. C meter which were used to water the plants. Vegetative and reproductive characterization was evaluated. Data obtained were subjected to one way analysis of variance using SPSS (20) Statistical Software. All the genotypes exhibited a decline significantly in vegetative and reproductive parameters measured, with increasing salt concentration. In conclusion, the result of this research suggest that salinity decline both vegetative and reproductive parameters in tomato.
Nature Imagined in S. T. Coleridge's "Meditative Poems" and Miguel de Unamuno's Poesías : A Study on Reception
Authors: Flores Moreno Cristina
Published: November 2018

This paper aims at exploring some aspects of Miguel de Unamuno’s engagement with Samuel Taylor Coleridge’s poetry. The Spanish author wrote in 1907 his first collection of poems, Poesías. To me, a non-negligible number of the poems in the collection bear significant resemblances with Samuel Taylor Coleridge’s “meditative” poems. It is my purpose here to analyse these similarities so as to prove that they are not mere chance, but the result of Unamuno’s attentive reading of Coleridge’s poems, which he frequently praised. Hence, a study of the Spanish author’s readings of the 1893 edition of The Works of S. T. Coleridge, now held in Unamuno’s private library in Salamanca, and the annotations he penned on its pages, will be offered first.
Carson McCullers and Lillian Smith : The Intersections of Gender and Race in the Jim Crow South
Authors: González Groba Constante
Published: November 2018

Carson McCullers and Lillian Smith openly rejected a false conception of loyalty to fantasies like southern tradition or white supremacy, a loyalty that veiled a persistent lack of self-analysis. They exposed the cracks in the South’s pretended “unity” and homogeneity and criticized the self-destructive resistance to acknowledge that, as a socially constructed category, race is linked to relations of power and anticipated the instability of racial categorization that would be underscored by historical and scientific research later in their century. These two southern women writers opposed the insistence of their culture on racial purity as vehemently as its demands for rigid sexual definition and its suppression of any deviant form of sexuality. The characters in their fiction are victims of a dichotomic culture that resists the acknowledgement that black and white have always been as inextricably linked as male and female.In Killers of the Dream and Strange Fruit, Lillian Smith showed the interactions of racial and sexual segregation, which she saw as parallel emblems of the South’s cultural schizophrenia. She was one of the first to detect the psychosexual damage inflicted on southern women by the racial discourse, and established a most interesting parallel between the segregated parts of the female body and the segregated spaces of any southern locality. Like any system of differentiation, segregation shapes those it privileges as well as those it oppresses. Excluded from the white parameters of virtue and even from the condition of womanhood, the black woman’s body became the sexual prey of the white man who could not demand sexual satisfaction from his “pure” wife. The culture of segregation privileged the white woman but it also made her powerless; the very conventions which “protected” her deprived her of contact with physicality and locked her into bodilessness.
A Defence of the Cliché
Authors: Haberer Adolphe
Published: November 2018

A sure thing is that clichés have a bad reputation. Trying to define the cliché as a linguistic or stylistic category, however, leads to all sorts of difficulties, as we seem to be dealing with “matters as imprecise as the shape and size of a cloud or the beginning and end of a wave”. Following the example of Louis MacNeice who once wrote a “Homage to Clichés”. in this paper I will take the defence of the cliché and show that in the terms of a (Lacanian) problematics of the subject’s enunciation it has its own function and significance.
Old English Ge- and the Descriptive Power of Nerthus
Authors: Martín Arista Francisco Javier
Published: November 2018

The main purpose of this article is to carry out an extensive examination of the evidence available of the Old English affix ge- in general, and, in particular, of the ge-alternation, which holds between predicates that bear a form-and-function contrast such as hlid ‘lid’~gehlid ‘roof’. The ge-alternation is examined as a pure and a mixed alternation, co-occurring with gradation, zero derivation and affixation. The conclusion is reached that ge- is the most frequent and the most widely distributed affix in Old English. Moreover, it partakes in inter-categorial and recursive derivation. As a secondary goal, this article aims at assessing the descriptive adequacy of the database of Old English derivational morphology Nerthus both on qualitative and quantitative grounds. In this respect, the conclusion is reached that the amount of evidence of ge- that can be drawn from Nerthus allows for an extensive analysis of the affix. On the other hand, Nerthus, in its present state, requires more accurate and formalised meaning definitions.
Wyndham Lewis and the Meanings of Spain
Authors: Munton Alan
Published: November 2018

Wyndham Lewis (1882-1957) visited Spain only twice, so far as is known. Yet the impact on his work was very significant. His novel The Revenge for Love (1937) is partly set in Spain, and is an important political novel of the 1930s; his painting The Siege of Barcelona (1936-37) is a significant statement about Spanish history and the Civil War. Less happy is the polemical essay Count Your Dead: They are Alive! (1937), which takes sides against the legitimate government. (He changed his mind the following year.) This discussion is based on themes apparent in Lewis’s understanding of Spain: his experience at the centre and on the margins; his overcoming of well-known clichés about Spain; his grasp of the importance of Spanish Anarchism; his recognition of the gaze or mirada as an element in life; and a final discussion of The Siege of Barcelona – which after 1939 was renamed The Surrender of Barcelona. That significant change indicates the seriousness of Lewis’s understanding of Spain.
English Studies : A Note on the Birth and Uses of the Term
Authors: Onega Susana
Published: November 2018

The need to adapt the current Spanish degree in English Philology to meet the requirements of the European Union has recently materialised in a growing conviction among scholars that the change of contents and format of the degree itself should be accompanied by a change of title, from “English Philology” to “English Studies”. This move justifies the present attempt to briefly recall some of the main lines of discussion involved in the birth and uses of the term in Britain and abroad.
"Bridge-uri, router-e si switch-uri" : On Romanian Computer Language
Authors: Pârlog Hortensia
Published: November 2018

The influence of English upon Romanian, which is not a new phenomenon, has become extensive in recent years. Words of English origin can be found, in greater or smaller numbers, in absolutely all Romanian newspapers and magazines, in advertisements, they can be heard on TV, can be seen as shop names or used in graffiti. The paper analyses terms that have been borrowed from English in the Romanian computer language. The data discussed have been collected from three issues, belonging to three different years, selected at random, of a Romanian computer magazine. One can easily notice that the rate of Anglicisms does not decrease with time, that some terms are totally unadapted and felt to be ’foreignisms’, while others display various degrees of morphological adaptation.
Revisiting FDA’s 1995 Guidance on Bioequivalence Establishment of Topical Dermatologic Corticosteroids: New Research Based Recommendations
Authors: Ozdin Deniz , Sharma Naveen , Lujan-Zilbermann Jorge , Colucci Philippe , Kanfer Isadore , Ducharme Murray P.
Published: November 2018

Purpose: As per the US FDA guidance issued on June 2, 1995, the establishment of bioequivalence for topical dermatologic corticosteroids is based on comparing the pharmacodynamic (PD) effects of Test and Reference products at the dose duration corresponding to the population ED50, determined either by naïve pooled data or nonlinear mixed effect modeling (NLME). The guidance was introduced using a study case example where the expectation maximization (EM) NLME algorithm, as implemented in P-PHARM®, was used. Although EM methods are relatively common, other methods such as the First-Order Conditional Estimation (FOCE) as implemented in the NONMEM® software are even more common. The objective of this study was to investigate the impact of using different parametric population modeling/analysis methods and distribution assumptions on population analysis results. Methods: The dose duration-response data from 11 distinct skin blanching blinded pilot studies were fitted using FOCE (NONMEM®) and an EM algorithm (ADAPT5® (MLEM)). Three different Emax models were tested for each method. Population PD estimates and associated CV%, and the agreement between model predicted values and observed data were compared between the two methods. The impact of assuming different distributions of PD parameters was also investigated. Results: The simple Emax model, as proposed in the FDA guidance, appeared to best characterize the data compared to more complex alternatives. The MLEM method in general appeared to provide better results than FOCE; lower population PD estimates with less inter-individual variability, and no variance shrinkage issues. The results also favored ln-normal versus normal distribution assumptions. Conclusions: The population ED50 estimates were influenced by both the type of population modeling methods and the distribution assumptions. We recommend updating the FDA guidance with more specific instructions related to the population approach to be used (EM-like versus FOCE-like methods) and to the normality assumptions that need to be set (ln-normal versus normal distribution).
Pentafluoropropionic Anhydride Functionalized PAMAM Dendrimer as miRNA Delivery Reagent
Authors: OZTUNA Ali , NAZİR Hasan
Published: November 2018

Poly(amidoamine) (PAMAM) dendrimers are good
candidates for nucleic acid delivery with their well-defined characteristics.
MicroRNA (miRNA) mediated regulation of biological process are also active area
of investigation. Fibroblast cells, such as MRC-5, are one of the cell lines
used in biological researches due to their hard to transfect nature. In this two-staged
study, cystamine core G5 PAMAM dendrimers were synthesized and modified with pentafluoropropionic
anhydride (PA) and subsequently tested as miRNA delivery reagent on MRC-5
cells. Effect of fluorination against to naked G5 dendrimer over transfection
efficiency was also investigated by molecular docking and quantitative
structure-activity relationship (QSAR) calculations. Structural
characterization of the synthesized dendrimers was verified by spectroscopic
techniques. Gel retardation assay, particle size and transmission electron
microscopy results demonstrated polyplex formation ability of fluorinated
dendrimers with miRNA at nanoscale level. Zeta potential values indicated
non-aggregation and increased stability of the polyplexes. Prepared polyplexes
with fluorinated dendrimer showed over 90% cell viability and transfection
efficiency. In silico calculations confirmed the stable complexation with miRNA
and smooth penetration capability into the cell.
The Impact of Tax Administration on Revenue Generation in Gombe State, Nigeria
Authors: Stephen N Emmanuel
Published: November 2018

Taxes have been the bedrock of revenue generation to any government. The administration of tax is very important to any government as it is the body responsible for implementing and governing the tax laws and other tax related to assessment, collection and remittance of tax. This study is aimed at ascertaining the effect of tax administration on revenue generation in Gombe state. The study uses survey research design. The primary source of data collection was adopted, which analysed using descriptive statistics was made up of frequencies and simple percentages. Cronbach's Alpha diagnose was carried out to seek for reliability of the questions contained in the questionnaire Three Hypotheses were presented in this research and were tested using Spearman’s Rank correlation, Pearson correlation and linear regression. Research findings indicated that Tax Administration in the state is not efficient and effective. The study revealed further that revenue generated in the state is low to meet its objectives due to low level of enlightenment of tax payers and incidents of tax evasion and tax avoidance. To this end, the study recommends, among others, that authorities should embark on more enlightenment campaign of citizens on the significance of paying Personal Income Tax, the quality and efficiency of tax workers should be improved so that more effective administration will be achieved and automation of the system.
Modular Visualization of Distributed Systems
Authors: Guevara Gustavo , Desell Travis , LaPorte Jason , Varela Carlos A.
Published: November 2018

Effective visualization is critical to developing, analyzing, and optimizing distributed systems. We havedeveloped OverView, a tool for online/offline distributed systems visualization, that enables modular layout mechanisms, so that different distributed system high-level programming abstractions such as actors or processes can be visualized in intuitive ways. OverView uses by default a hierarchical concentric layout that distinguishes entities from containers allowing migration patterns triggered by adaptive middleware to be visualized. In this paper, we develop a force-directed layout strategy that connects entities according to their communication patterns in order to directly exhibit the application communication topologies. In force-directed visualization, entities`'  locations are encoded with different colors to illustrate load balancing. We compare these layouts using quantitative metrics including communication to entity ratio, applied on common distributed application topologies. We conclude that modular visualization is necessary to effectively visualize distributed systems since no one layout is best for all applications.
A Cosmological View on Milgrom’s Acceleration Constant
Authors: Roza Engel
Published: November 2018

In this article it is shown how Milgrom’s acceleration constant is related with the ΩΛ, Ωm and ΩB values of the matter distribution within observable universe as defined in the Standard Model of Cosmology, established by the Planck Collaboration Group. The result is a two-parameter model for the observable universe. The two parameters are the age of the universe and Milgrom’s acceleration constant. It is shown that these are sufficient to calculate the amounts of matter and dark energy in the universe, as well as the contributions of dark matter and baryonic matter in the matter part. The numerical results are in agreement with those of the Lamda-CDM model.
Design and Development of a GSM-based Smart Home Automation System
Authors: Reza Selim , Mamun SM , Munna Monjur Mossadded
Published: November 2018

Home Security Systems are very important features of modern residential and office setups. This system is used to keep home safe from harmful gases, fire and intruders. It must be affordable, reliable and effective. In this paper, a GSM based home security system has been designed and implemented. The system consists of a GSM Module, MQ-2 smoke detector, Ultrasonic sonar sensor, LM35 temperature sensor, Arduino Uno and relay module. The MQ-2 smoke detector is used to detect harmful gases i.e. LPG, CH4, CO, Alcohol, Smoke or Propane. Any of the harmful gases stated above is detected it will warn the owner by activating the buzzer and displaying a warning message on the LCD display. It will also send a SMS to the owner. Our system can also measure temperate and if the temperature is increased above a certain range it will compensate it by activating Air Conditioner through the relay module. The system will also send a SMS to the owner. It can also detect intruders using Ultrasonic sensor and warn us through buzzer, SMS and displaying message on the LCD. Our system is reliable as it has very fast response and cost effective and it has been developed using our own technologies.