bluuebunny/crossref_metadata_2025 huggingface dataset:
A Scenario-Based Simulation of Land System Changes on Dietary Changes: A Case Study in China
Authors: Huang Jincheng , Liu Yueyan , Zhang Xiaoying , Wang Yu , Wang Yisong
Published: September 2019

The dietary change of Chinese residents is driven by increasing incomes and urbanization, which will bring about non-negligible changes in the food production of the land system. To explore how dietary changes might influence future land systems and the environment, this research hypothesizes two potential dietary change scenarios in the period 2010–2030, based on the current trends and Dietary Guidelines for Chinese Residents (DGCR), and applies the CLUMondo model to simulate the spatiotemporal patterns of land systems and estimates a lifecycle’s environmental impacts on dietary change. As shown in the results, dietary changes would obviously alter the land cover, agricultural intensity, and livestock density of land systems, and the changes in land use intensity are noteworthy. If the current trend of dietary change is unchecked, the intensification and expansion of agriculture and animal husbandry would be widely distributed in North China and Northwest China, where the intensity of cropland was low in the past and the ecosystem was relatively fragile. Moreover, the increasing demands for food lead to sharp increases in the carbon footprint, water footprint, and ecological footprint from food production. In contrast, the balanced diet recommended by DGCR could offer considerable environmental benefits. This diet is conducive to cutting down land use intensity, helping natural systems avoid intensification, and the expansion of agriculture and animal husbandry, which lower footprints from food production and have helped to implement the policy of returning croplands to grassland and forests in China. Therefore, popularizing balanced diets could be a win–win for human health and environmental sustainability.
The Truth behind the Brexit Vote: Clearing away Illusion after Two Years of Confusion
Authors: Chung Sae Won , Kim Yongmin
Published: September 2019

Since the referendum in 2016, Brexit has become the most controversial conundrum in the UK. This study aimed to revisit this issue by focusing on the communicative patterns of Brexit-related parties (the Conservatives, Labour, and UK Independence Party). Firstly, it attempted to provide the conceptual backgrounds of Brexit by explaining its development process from Cameron’s pledge of an in/out referendum to the present. Subsequently, it reviewed empirical studies on Brexit in diverse areas of social science. Most empirical studies point out that British political practitioners’ perceptions about Brexit were the root cause, but they were not able to provide an overview of these perceptions. The novelty of this study lies in examining the patterns of these perceptions by focusing on communicative framings embedded in the posts created in their official Facebook pages from the date of the referendum to that of the Brexit withdrawal agreement. To extract these framings, this study adopted an automated semantic network analysis geared by NodeXL—software for data collection and visualisation. The results show that these parties emphasised that they were the only legitimate political party to solve the Brexit crisis without providing concrete solutions or measures. These parties’ ill-founded communications endanger sustainable social media communications and interactions in the UK. Hence, it is vital to establish a more reliable fact-checking information-sharing system between the political elite and the general public.
Challenges of Regional Development in the Context of Population Ageing. Analysis Based on the Example of Opolskie Voivodeship
Authors: Heffner Krystian , Klemens Brygida , Solga Brygida
Published: September 2019

Demographic changes, primarily the problem of progressive ageing, are one of the key challenges to development in Poland. The Opolskie voivodeship belongs to the regions characterised by extremely unfavourable demographic phenomena. This is because some population changes here have a broader dimension than on average in Poland and in the EU. Thereby, they have far-reaching as well as complex economic and social consequences in the region. Due to the fact that demographic processes are determined in the long term, and it is extremely difficult to influence them in the short term, the adaptation of social and economic spheres and, at the same time, the use of specific opportunities resulting from these changes, seems a useful strategy for regional development policy. Therefore, in the context of senioral policy, complex, coherent and diversified activities in the sphere of growth of professional activity of elderly people, support for life-long learning, improvement of seniors’ living conditions, including the development of health infrastructure, and seniors’ integration in society prove to be necessary. The multidimensional concept of the ‘silver economy’ creates specific opportunities for using the possibilities resulting from population ageing, and minimising the unfavourable consequences of this process, in the Opolskie voivodeship. However, the implementation of this concept demands the consideration of several determinants and barriers, that consequently affect its effective functioning. The direct objective of the paper is to present the current and projected demographic situation of Opolskie voivodeship, and on its basis, to determine the challenges resulting from the ageing of society for regional development.
Integrating Satellite-Derived Data as Spatial Predictors in Multiple Regression Models to Enhance the Knowledge of Air Temperature Patterns
Authors: Alonso Lucille , Renard Florent
Published: September 2019

With the phenomenon of urban heat island and thermal discomfort felt in urban areas, exacerbated by climate change, it is necessary to best estimate the air temperature in every part of an area, especially in the context of the on-going rationalization weather stations network. In addition, the comprehension of air temperature patterns is essential for multiple applications in the fields of agriculture, hydrology, land development or public health. Thus, this study proposes to estimate the air temperature from 28 explanatory variables, using multiple linear regressions. The innovation of this study is to integrate variables from remote sensing into the model in addition to the variables traditionally used like the ones from the Land Use Land Cover. The contribution of spectral indices is significant and makes it possible to improve the quality of the prediction model. However, modeling errors are still present. Their locations and magnitudes are analyzed. However, although the results provided by modelling are of good quality in most cases, particularly thanks to the introduction of explanatory variables from remote sensing, this can never replace dense networks of ground-based measurements. Nevertheless, the methodology presented, applicable to any territory and not requiring specific computer resources, can be highly useful in many fields, particularly for urban planners.
African Swine Fever: Fast and Furious or Slow and Steady?
Authors: Schulz Katja , Conraths Franz Josef , Blome Sandra , Staubach Christoph , Sauter-Louis Carola
Published: September 2019

Since the introduction of African swine fever (ASF) into Georgia in 2007, the disease has been spreading in an unprecedented way. Many countries that are still free from the disease fear the emergence of ASF in their territory either in domestic pigs or in wild boar. In the past, ASF was often described as being a highly contagious disease with mortality often up to 100%. However, the belief that the disease might enter a naïve population and rapidly affect the entire susceptible population needs to be critically reviewed. The current ASF epidemic in wild boar, but also the course of ASF within outbreaks in domestic pig holdings, suggest a constant, but relatively slow spread. Moreover, the results of several experimental and field studies support the impression that the spread of ASF is not always fast. ASF spread and its speed depend on various factors concerning the host, the virus, and also the environment. Many of these factors and their effects are not fully understood. For this review, we collated published information regarding the spreading speed of ASF and the factors that are deemed to influence the speed of ASF spread and tried to clarify some issues and open questions in this respect.
Medical Outcomes in Women Who Became Pregnant after Vaccination with a Virus-Like Particle Experimental Vaccine against Influenza A (H1N1) 2009 Virus Tested during 2009 Pandemic Outbreak
Authors: Cérbulo-Vázquez Arturo , Arriaga-Pizano Lourdes , Cruz-Cureño Gabriela , Boscó-Gárate Ilka , Ferat-Osorio Eduardo , Pastelin-Palacios Rodolfo , Figueroa-Damian Ricardo , Castro-Eguiluz Denisse , Mancilla-Ramirez Javier , Isibasi Armando , López-Macías Constantino
Published: September 2019

The clinical effects and immunological response to the influenza vaccine in women who later become pregnant remain to be thoroughly studied. Here, we report the medical outcomes of 40 women volunteers who became pregnant after vaccination with an experimental virus-like particle (VLP) vaccine against pandemic influenza A(H1N1)2009 (influenza A(H1N1)pdm09) and their infants. When included in the VLP vaccine trial, none of the women were pregnant and were randomly assigned to one of the following groups: (1) placebo, (2) 15 μg dose of VLP vaccine, or (3) 45 μg dose of VLP vaccine. These 40 women reported becoming pregnant during the follow-up phase after receiving the placebo or VLP vaccine. Women were monitored throughout pregnancy and their infants were monitored until one year after birth. Antibody titers against VLP were measured in the mothers and infants at delivery and at six months and one year after birth. The incidence of preeclampsia, fetal death, preterm delivery, and premature rupture of membranes was similar among groups. All vaccinated women and their infants elicited antibody titers (≥1:40). Women vaccinated prior to pregnancy had no adverse events that were different from the nonvaccinated population. Even though this study is limited by the sample size, the results suggest that the anti-influenza A(H1N1)pdm09 VLP experimental vaccine applied before pregnancy is safe for both mothers and their infants.
Interaction of a Densovirus with Glycans of the Peritrophic Matrix Mediates Oral Infection of the Lepidopteran Pest Spodoptera frugiperda
Authors: Pigeyre Laetitia , Schatz Malvina , Ravallec Marc , Gasmi Leila , Nègre Nicolas , Clouet Cécile , Seveno Martial , El Koulali Khadija , Decourcelle Mathilde , Guerardel Yann , Cot Didier , Dupressoir Thierry , Gosselin-Grenet Anne-Sophie , Ogliastro Mylène
Published: September 2019

The success of oral infection by viruses depends on their capacity to overcome the gut epithelial barrier of their host to crossing over apical, mucous extracellular matrices. As orally transmitted viruses, densoviruses, are also challenged by the complexity of the insect gut barriers, more specifically by the chitinous peritrophic matrix, that lines and protects the midgut epithelium; how capsids stick to and cross these barriers to reach their final cell destination where replication goes has been poorly studied in insects. Here, we analyzed the early interaction of the Junonia coenia densovirus (JcDV) with the midgut barriers of caterpillars from the pest Spodoptera frugiperda. Using combination of imaging, biochemical, proteomic and transcriptomic analyses, we examined in vitro, ex vivo and in vivo the early interaction of the capsids with the peritrophic matrix and the consequence of early oral infection on the overall gut function. We show that the JcDV particle rapidly adheres to the peritrophic matrix through interaction with different glycans including chitin and glycoproteins, and that these interactions are necessary for oral infection. Proteomic analyses of JcDV binding proteins of the peritrophic matrix revealed mucins and non-mucins proteins including enzymes already known to act as receptors for several insect pathogens. In addition, we show that JcDV early infection results in an arrest of N-Acetylglucosamine secretion and a disruption in the integrity of the peritrophic matrix, which may help viral particles to pass through. Finally, JcDV early infection induces changes in midgut genes expression favoring an increased metabolism including an increased translational activity. These dysregulations probably participate to the overall dysfunction of the gut barrier in the early steps of viral pathogenesis. A better understanding of early steps of densovirus infection process is crucial to build biocontrol strategies against major insect pests.
Novel Genetic Rearrangements Termed “Structural Variation Polymorphisms“ Contribute to the Genetic Diversity of Orthohepadnaviruses
Authors: Fujiwara Kei , Matsuura Kentaro , Matsunami Kayoko , Iio Etsuko , Nagura Yoshihito , Nojiri Shunsuke , Kataoka Hiromi
Published: September 2019

The genetic diversity of orthohepadnaviruses is not yet fully understood. This study was conducted to investigate the role of structural variations (SVs) in their diversity. Genetic sequences of orthohepadnaviruses were retrieved from databases. The positions of sequence gaps were investigated, since they were found to be related to SVs, and they were further used to search for SVs. Then, a combination of pair-wise and multiple alignment analyses was performed to analyze the genomic structure. Unique patterns of SVs were observed; genetic sequences at certain genomic positions could be separated into multiple patterns, such as no SV, SV pattern 1, SV pattern 2, and SV pattern 3, which were observed as polymorphic changes. We provisionally referred to these genetic changes as SV polymorphisms. Our data showed that higher frequency of sequence gaps and lower genetic identity were observed in the pre-S1-S2 region of various types of HBVs. Detailed examination of the genetic structure in the pre-S region by a combination of pair-wise and multiple alignment analyses showed that the genetic diversity of orthohepadnaviruses in the pre-S1 region could have been also induced by SV polymorphisms. Our data showed that novel genetic rearrangements provisionally termed SV polymorphisms were observed in various orthohepadnaviruses.
Experimental Investigation of Flood Energy Dissipation by Single and Hybrid Defense System
Authors: Ahmed Afzal , Ghumman Abdul Razzaq
Published: September 2019

In this study, a series of laboratory experiments were conducted to investigate the energy loss through the hybrid defense system (HDS) in the order of dike, moat, and emergent vegetation in steady subcritical flow conditions. The results of HDS were compared with a single defense system (SDS) comprising only vegetation (OV). The dimensions of dike were kept constant while two different shapes (trapezoidal and rectangular) of moat were considered. The impacts of vegetation of variable thickness and density were investigated. Two combinations of HDS were investigated including the combination of dike and vegetation (DV) and the combination of dike, moat, and vegetation (DMV). The effect of backwater rise due to the vegetation, hydraulic jump formation and the impact of the arrival time of floodwater on energy dissipation were investigated. It was observed that on the upstream side of obstructions, the backwater depth increased by increasing the Froude number in both the SDS and HDS. The hydraulic jump observed in HDS was classified and the energy dissipation due to it was calculated. Under various conditions investigated in this paper, the maximum average energy dissipation was 32% in SDS and 46% in HDS. The trapezoidal moat performed better than rectangular moat as energy dissipater. The delay time was also greater with trapezoidal moat as compared to that in rectangular one. The maximum delay time was 140 s in the case of HDS. Hence, the hybrid defense system offered maximum resistance to the flow of water, thus causing a significant energy loss. For each case of SDS and HDS, empirical equations were developed by regression analysis to estimate the energy dissipation amounts.
Impacts of Climate Change Scenarios on Non-Point Source Pollution in the Saemangeum Watershed, South Korea
Authors: Li Ting , Kim Gwangseob
Published: September 2019

Non-point source (NPS) pollution is a primary cause of water pollution in the Saemangeum watershed in South Korea. The changes in NPS pollutant loads in the Saemangeum watershed for an 81-year period (2019–2099) were simulated and analyzed by applying the soil and water assessment tool. Six climate model (BCC-CSM1–1, CanESM2, GFDL-ESM2G, HadGEM2-CC, INM-CM4, and MIROC-ESM) outputs using representative concentration pathway (RCP) scenarios (RCP 4.5 and RCP 8.5) were obtained from the South Korean Asia-Pacific Economic Cooperation (APEC) Climate Center. Simulated streamflow and water quality were evaluated using the Nash–Sutcliffe efficiency (NSE) index and coefficient of determination (R2). The model satisfactorily simulated streamflow with positive NSE values and R2 > 0.5. Based on two climate change scenarios (RCP 4.5 and RCP 8.5), gradual increases of 70.9 to 233.8 mm and 1.7 to 5.7 °C in annual precipitation and temperature, respectively, are likely for two time periods (2019–2059 and 2060–2099). Additionally, the expected future average annual and monthly streamflow, sediment, and total phosphorus showed changes of 5% to 43%, 3% to 40%, and −55% to 15%, respectively, whereas the expected future average annual and monthly total nitrogen showed decreases of −5% to −27%. Future NPS pollutant loads in the Saemangeum watershed should be managed according to different climate change scenarios.
Degrees and Forms of Commercialization: Community-Managed Water Operators in Lamongan Regency, Indonesia
Authors: Tutusaus Mireia , Surya Risky Aditya , Schwartz Klaas
Published: September 2019

Globally, the water services sector has adopted commercial principles since the 1980s and 1990s. Most of the reforms based on these principles have been introduced as part of broader neoliberal reforms in these countries. Often these reforms are portrayed as being homogenous and standardized, suggesting there is a shared understanding of commercialization. However, in recent years, scholars have explored the lack of universality of these principles when comparing the implementation of these reforms across settings. Across different countries significant differences in implementation and outcomes of commercialization can be identified. In much of this literature, emphasis is placed on the differences visible in the implementation of commercialization across different geographical areas. In this article, we contribute to this literature by questioning the universal application of the principles of commercialization even within the same geographical area and actor. Using the case of community-based organizations in Lamongan Regency, Indonesia, this paper elaborates on the multiple manifestations of commercialization when documenting the actual practices of water operators. We argue that, within even the operations of these water operators, commercial principles are indeed differently implemented from the original commercial model of water provisioning. The deviations from the model can be attributed to not only local conditions under which the water providers operate, but also reflect the interests of the implementing agency and its environment. The deviations from the model of commercialization lead to questions about the validity of this model as they re-interpret key principles of the model. Yet, we find that little of these divergences and re-interpretations are reported upon. As a result, these two models of commercialization, the one practiced by the water operator and the one endorsed by donors and sector organizations co-exist as separate, and equally valid, guidelines. We advocate for a richer vocabulary to describe or refer to different manifestations and interpretations of commercialization as this may lead to a more honest development of water services for all.
Design and Experimental Verification of Voltage Measurement Circuits Based on Linear Optocouplers with Galvanic Isolation for Battery Management Systems
Authors: Dimitrov Borislav , Collier Gordana , Cruden Andrew
Published: September 2019

A battery management system (BMS) design, based on linear optocouplers for Lithium-ion battery cells for automotive and stationary applications is proposed. The critical parts of a BMS are the input voltages and currents measurement circuits. In this design, they include linear optocouplers for galvanic isolation between the battery pack and the BMS. Optocouplers based on AlGaAs light emitted diodes (LED) and PIN photodiode with external operational amplifiers are used. The design features linear characteristics, to ensure the accuracy of the measurements. The suggested approach is based on graphical data digitalizing, which gives the precise values for the most sensitive parameters: photocurrent, normalized and transferred servo gain and helps the calculation procedure to be automated with MATLAB scripts. Several mathematical methods in the analysis are used in order for the necessary equations to be derived. The results are experimentally verified with prototypes.
Inclusión financiera en el desarrollo económico de los microempresarios del cantón Cayambe
Authors: Altamirano Salazar Washington Aniabal , Cruz Guevara Marcelo Raúl , Arroyo Burbano Ingrid Karina , Cumbajin Pila Daniela Liseth
Published: September 2019

A nivel mundial existen más de 200 millones de microempresas que carecen del financiamiento adecuado para prosperar y crecer, las microempresas ecuatorianas están dentro de este escenario debido a la falta de una adecuada inclusión financiera que les brinde oportunidades de desarrollo económico. En este contexto, es importante determinar cómo influye la inclusión financiera en el desarrollo económico en los microempresarios, para el efecto, se utilizó 271 microempresas del cantón Cayambe. Los resultados determinan que los microempresarios formales poseen el 78,80% de inclusión financiera, de los cuales únicamente el 10,8% no han accedido al financiamiento otorgado por una entidad financiera. En cuanto a los informales solamente el 48,30% posee inclusión, de los cuales el 33,8% no ha accedido a ningún tipo de financiamiento; demostrándose un mayor desarrollo económico en el sector formal debido a que la Inclusión Financiera tiene una relación significativa y ejerce efectos positivos en el desarrollo económico de los microempresarios.
 
Palabras clave: inclusión financiera, desarrollo económico, microempresas, ecuaciones estructurales.
 
ABSTRACT
Worldwide there are more than 200 million microenterprises, which lack adequate financing to thrive and grow, Ecuadorian microenterprises are in this scenario due to the lack of adequate financial inclusion that provides economic development opportunities. In this context, it is important to determine how financial inclusion influences the economic development of microentrepreneurs. For this purpose, 271 micro enterprises of the Cayambe canton were used. The results determine that formal microentrepreneurs have a 78.80% financial inclusion, of which only 10.8% have not accessed the financing granted by a financial institution. As for the informal only 48.30% .posen inclusion, of which 33.8% has not agreed to any type of financing. Demonstrating greater economic development in the formal sector due to the fact that Financial Inclusion has a significant relationship and exerts positive effects on the Economic Development of microentrepreneurs.
 
Key words: financial Inclusion, Economic Development, Microenterprises, Structural Equations.
OFICINAS DE CÁLCULO MENTAL E CALCULADORA: PESQUISA E PRÁTICA NA FORMAÇÃO DE PROFESSORES DE MATEMÁTICA NO CURSO DE LICENCIATURA EM EDUCAÇÃO DO CAMPO DA UFMG
Authors: Nunes Laís Macedo de Almeida , Pinto Nayara Katherine Duarte , Grossi Flávia Cristina Duarte Pôssas , Conti Keli Cristina
Published: September 2019

Este artigo busca apresentar aspectos teóricos significativos do cálculo mental e da calculadora, bem como discorrer sobre as vantagens de se desenvolver um trabalho com essas duas competências de cálculo em sala de aula. O foco do trabalho é apresentar considerações sobre a formação de professores de Matemática a partir de duas oficinas sobre a calculadora e o cálculo mental realizadas no Laboratório de Ensino de Matemática da Faculdade de Educação da Universidade Federal de Minas Gerais. As oficinas tiveram como público-alvo estudantes do curso de Licenciatura em Educação no Campo  Habilitação Matemática  e objetivaram proporcionar momentos de reflexões e práticas sobre o cálculo mental e a calculadora na sala de aula, de maneira a estimular esses futuros professores a utilizarem essas duas modalidades de cálculo em suas turmas da Educação Básica. Os dados que subsidiaram a análise foram produzidos a partir de registros em áudio, registros fotográficos e questionários aplicados aos licenciandos. Após um retorno positivo dos participantes das oficinas, concluímos e salientamos a relevância dessas temáticas terem sido trabalhadas na oficina de maneira a complementar a formação inicial dos futuros professores de Matemática.
Saberes da gente do mar
Authors: Rodrigues Jaime
Published: September 2019

Apresenta a transcrição do Breve compendio do que pertence à obrigação de hum capitão de mar & guerra, manuscrito datado de 1676. O original, depositado na Biblioteca Nacional de Portugal, provavelmente era utilizado no ensino militar e náutico, escrito sob a forma de um diálogo entre um capitão e um artilheiro a ele subordinado. O documento enumera as qualidades que um capitão de mar e guerra deveria ter, os nomes das partes de um navio e os conhecimentos que deveriam ser detidos pelos marinheiros/soldados.
F.H Jacobi e o evangelho do idealismo transcendental
Authors: Langer Douglas William
Published: September 2019

O objetivo deste trabalho é analisar a discussão envolvendo J.G Fichte e F.H Jacobi na conhecida Atheismusstreit debate no qual Fichte é acusado de ateísmo e niilismo por Jacobi baseando-se na dificuldade fichteana em deduzir o mundo empírico a partir do princípio puro da sua Wissenschaftslehre, o Eu, sem trair os preceitos transcendentais de sua doutrina. A investigação se concentrará com mais ênfase na extensa resposta de Fichte no seu Bestimmung des Mensch (1800) onde procura destacar o âmbito moral da sua filosofia como uma solução a esterilidade da pureza do campo teórico, isto é, com a fé funcionando como o órgão pelo qual o chamado da vontade é aceito e o mundo, agora moral, é deduzido. Esta fé traça uma tangente entre ambos, uma vez que Jacobi também a concebe em seu David Hume über den Glauben oder Idealismus und Realismus (1787) com a diferença fundamental de que em Fichte esta fé se segue da deliberação livre do agente, uma fé em sua própria natureza racional, enquanto em Jacobi ela é consequente da revelação miraculosa da objetividade advinda de Deus, uma transcendência absoluta.
Número Completo
Authors: Revista de Filosofía y Ciencias Prometeica
Published: September 2019

Número Completo
Editorial
Authors: Judensnaider Ivy
Published: September 2019

Editorial
Análise socioeconômica do turismo comunitário na Comunidade Indígena Nova Esperança, RDS Puranga Conquista (AM)
Authors: Porto Nailza Pereira , Proença Ana Rosa Guimarães Bastos
Published: September 2019

O turismo é uma das alternativas de uso público das Áreas Protegidas (AP), portanto é imprescindível que seja ordenado de forma a contribuir com a preservação socioambiental, além de proporcionar emprego e renda aos moradores locais e do entorno dessas áreas. Nesse contexto, tem-se o Turismo Comunitário (TC), um planejamento ou forma de turismo aliado ao desenvolvimento local e ao protagonismo comunitário. Assim, este artigo tem como objetivo apresentar análise socioeconômica do turismo comunitário na Comunidade Indígena Nova Esperança (AM). A comunidade localiza-se na Reserva de Desenvolvimento Sustentável (RDS) Puranga Conquista, no estado do Amazonas (BR) a cerca de 81km da capital, Manaus. A pesquisa tem caráter qualitativo e quantitativo, utilizando-se de levantamento bibliográfico, documental e pesquisa de campo com as técnicas pesquisa participante, com aplicação de formulários e oficinas com ferramentas participativas para mensurar a contribuição das principais atividades econômicas na comunidade, levando em consideração as vantagens comparativas. Tais técnicas, tiveram a finalidade de demonstrar qual a contribuição da atividade turística na complementariedade das atividades tradicionais, não apenas no aspecto financeiro como também culturais e ambientais. A partir disso, se evidencia a importância da pluralidade de atividades econômicas para superar a sazonalidade turística que influencia diretamente no faturamento das famílias residentes em  RDS’s. Como contribuição, as informações apresentadas poderão ser relevantes para o planejamento do turismo comunitário no local, buscando minimizar os impactos e otimizar os recursos para a operacionalização e a compatibilização das atividades econômicas, culturais e ambientais da comunidade com a atividade turística.
EVALUATION OF ENDODONTIC TREATMENT OUTCOMES OF VERTICAL CONDENSATION TECHNIQUE USING TOUCH’N HEAT DEVICE
Authors: Hoang Anh Dao , Nguyen Thi Thu Nhung
Published: September 2019

Background: One of the key factors in successful endodontic therapy is to adequately fill the root canals. Vertical condensation technique is regarded as a high probability of three-dimensional filling of root canal space which is required to achieve long-term success.

Aim: To evaluate the endodontic treatment outcomes of vertical condensation technique using Touch’N Heat device.

Subjects and methods: A prospective, descriptive study was conducted across two hospitals in Hue city from 11/2016 to 5/2017. All teeth were instrumented by manual Protaper files and obturated by the vertical condensation technique with Touch’N Heat device. The radiographic evaluation for initial assessment of obturation quality was performed. Evaluation of endodontic treatment outcomes in terms of clinical symptoms and radiographic assessment were recorded after 3-month follow-up.

Results: A sample of 30 patients (with 39 incisors) from 13 to 73 years old was recruited. The principal reasons for visiting were pain (30.8%), decay (20.5%) or trauma (20.5%). Most patients seeked treatment at chronic stage of diseases with chronic pulpitis (38.4%) and chronic periapical periodontitis (30.8%). In radiographical quality of obturation, there were 27 (69.3%) fulllength obturated teeth, 8 (20.5%) overfilled teeth (sealer). The percentage of homogeneity of root canal filling was 82.1%. Over 82% patients (25 patients with 32 teeth) presented after there-months followup. Clinical assessment yeiled 30 (93.7%) “adequate” teeth, 2 (6.3%) “poor” teeth. Refer to radiographical assessment, the teeth were defined as “success”, “questionable” and “failure” (29 teeth (90.6%), 3 teeth (9.4%) and zero, respectively).

Conclusions: The vertical condensation using Touch’N Heat device ensure the full-length obturation, high homogenetious root canal filling, and sucessful prognosis in clinical and radiographic outcomes.

Key words: vertical condensation,Touch’N Heat, endodontic outcomes
PREVALENCE OF COGNITIVE IMPAIRMENT AND ASSOCIATED FACTORS AMONG THE ELDERLY IN PHU AN COMMUNE, PHU VANG DISTRICT, THUA THIEN HUE PROVINCE IN 2016
Authors: Huynh Thi Thanh Tu , Doan Vuong Diem Khanh , Nguyen Thi Hanh , Le Thi Thao Nguyen , Tran Thi Phuong Linh , Nguyen Nhat Manh
Published: September 2019

Background: Cognitive impairment is one of the major causes of disability and dependency among the elderly. Cognitive impairment not only seriously affects the quality of the patient’s life but also has a great impact on physical, psychological and economic situation of family caregivers and society. There is little research on the prevalence of cognitive impairment and its related factors in Vietnam. Aims: The aims of this study were: (i) To examine the prevalence of cognitive impairment among the elderly in Phu An commune, Phu Vang district, Thua Thien Hue province (ii) To examine some associated factors of cognitive impairment among participants. Methods: A randomly selected sample of 343 people aged 60 years and over living in Phu An commune were interviewed and examined. MMSE test (Mini Mental State Examination) was used as a screening instrument for cognitive impairment. Multilogistic regression was undertaken for exploring associated factors of cognitive impairment. Results: The overall prevalence of cognitive impairment was 19.5%. Increasing age, inconvenient marital status (single, widowed, separate), living alone were associated with increasing risk of acquiring cognitive impairment. Conclusion: In this population, probable cognitive impairment is common. Health education program and routine health checkup for early detection and intervention of cognitive impairment are urgently needed among the elderly in Vietnam.

Key words: Cognitive impairment, prevalence, associated factors, elderly people
SCREENING ON XANTHINE OXIDASE INHIBITORY ACTIVITY OF SOME VIETNAM MEDICINAL PLANTS
Authors: Nguyen Dinh Quynh Phu , Pham Thi Hien Thu , Nguyen Thi Hoai
Published: September 2019

Background: Xanthine oxidase inhibitory activity was assayed from twelve species used for the treatment of gout and related activity such as antioxidant, anti-inflammatory and analgesic activity by indigenous people of Vietnam.

Materials and method: The leaves of these plants were extracted with methanol solvent and then to test the xanthine oxidase inhibitory activity in vitro through the modified Tadataka Noro’s spectrophotometric method.

Results: Of the 36 extracts assayed, 11 extracts demonstrated xanthine oxidase inhibitory activity at 100μg/ml, 8 extracts demonstrated xanthine oxidase inhibitory activity at 50μg/ml and 2 extracts demonstrated xanthine oxidase inhibitory activity at 10μg/ml. The methanol extracts of Bryophyllum pinnatum and Annona glabra showed an inhibition greater than 50%.

Conclusion: The methanol extracts of Bryophyllum pinnatum (Lam.) Kurz. (Crassulaceae) and Annona glabra L. (Annonaceae) presented xanthine oxidase inhibitory activity with IC50 values of 59.42 and 70.92μg/ml, respectively.

Key words: Vietnamese medicinal plants, Xanthine oxidase inhibitory activity, Gout
METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF METOPROLOL IN HUMAN PLASMA BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
Authors: Nguyen Viet Khan , Nguyen Thị Hoai
Published: September 2019

Background: Metoprolol has been widely used in the treatment of hypertension. The usage of drugs for cardiovascular diseases is highly required safety and effectiveness for patients. Therefore, a convenient method for the determination of metoprolol in plasma is necessary.

Objectives: (1) To develope an HPLC method for quantification of metoprolol in human plasma and (2) To validate of the method.

Materials and methods: human plasma.

Results: Chromatographic conditions include: Eclipse XDB-C18 column, fluorescence detector, mobile phase: acetonitril : NaH2PO4 buffer (25 mmol/L, pH 3.0) with a solvent gradient program. The analytical method met current FDA guidelines for bioanalytical method validation.

Conclusions: The method can be applied to determine metoprolol in biological fluids for pharmacokinetic and biocompatibility study.

Key words: Metoprolol, plasma, HPLC
ASSESSMENT OF DRUG INTERACTIONS IN OUTPATIENT PRESCRIPTIONS IN HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Vo Thi Hong Phuong , Nguyen Thi Hien
Published: September 2019

Background: The combination of drugs in treatment is inevitable, especially in multiple diseases and multiple symptoms. This is the leading cause of occurrence of drug - drug interactions.

Objectives:

(1) To identify clinically significant drug interactions in outpatient prescriptions in Hue University of Medicine and Pharmacy Hospital,
(2) To build a management guideline of clinically significant drug interactions in Hue University of Medicine and Pharmacy Hospital.

Materials and methods: 5338 outpatient prescriptions were collected from Pharmacy Faculty – Hue University of Medicine and Pharmacy Hospital from 1st to 31st October 2017, using cross-sectional descriptive study method.

Results and Conclusion: The list of 20 clinically significant drug interaction pairs was identified and a management guideline for each interacting pair was built. The prevalence of prescriptions with drug interactions was 6.7%. The most commonly identified drug interaction pair was clopidogrel and proton pump inhibitor (1.59%). The occurrence of drug interactions increased with increase in the age of patients and the number of drugs prescribed (p < 0.05).

Key words: combination of drugs, drug interaction, clinically significant, prescription, outpatient
Dietetic Management of Lipid Profile in an Adult Population from the Italian Region of Abruzzo: Role of Mediterranean Diet
Authors: Gammone Maria Alessandra , Martelli Stefania , Danese Antonella , D’Orazio Nicolantonio
Published: September 2019

Background: There has long been a lot of debate about the role of nutrition in the pathogenesis of cardio- vascular diseases. Monounsaturated and polyunsaturated fatty acids, especially n-3 PUFAs are the types of fat that favor metabolic markers and represent central components of the Mediterranean diet, which is considered an ideal dietary pattern with great cardio protective effect.
Aim: This study aims to assess the influence of Mediterranean diet on lipid metabolism, compared to not-Mediterranean hypocaloric dietary patterns.
Materials and Methods: This prospective clinical trial evaluated total cholesterol, LDL, HDL, and triglycerides and their modifications in a group of adults in relation to the two different kinds of diet: on the one hand the typical western dietetic pattern, characterized by higher intakes of red meat, dairy products and refined grains, low consumption of fruits and vegetables (L-diet), and the Mediterranean diet (M-diet).
Gamification for Healthcare and Well-being
Authors: Udara S.W.I. , De Alwis A.K.
Published: September 2019

Good health is one’s greatest asset. There are many software solutions, developed to help improve the health, and well-being of people, along with them gamified software solutions are popular with their greatest effectiveness and experience compared to physical medication. While there are solutions, developed with the proper understanding of the scientific effect of such solutions to people, some are developed without any scientific analysis or proved results. This paper discusses the main health issues of humans identified within the past decade and what gamification solutions have been implemented to mitigate them and how feasible they have been. Moreover, this article discusses the future development and trends of such gamified solutions for healthcare. Compared to physical treatments and medication, gamification provides an immersive experience with the user’s mind strongly connected with the game play, which is a great place to improve the health of a person using psychology. Many people enjoy games in their leisure time, and some use them to kill time, but games can be used for much more significant purposes connected with psychology and various functions of the human brain. Some health issues can be cured just by the perception of a person’s mind since there are many hormones in the body, which reacts to countless feelings, thoughts, and sensations, that could even cure a person without medicine.
HUMAN CAPITAL INVEST AND OUTCOMES (STUDI PADA TRANSFER PEMBELIAN CRISTIANO RONALDO OLEH MANAJEMEN JUVENTUS FC)
Authors: Septiawan Bambang
Published: September 2019

This research focuses on investigating the consideration of Juventus FC management for recruiting Cristiano Ronaldo related to human capital invest and outcomes context. Most of theory used in this research is about human capital invest and result or outcomes by Burud and Tumolo. It is descriptive research because it seeks to understand fenomena. The scope of this research is about financial and the subjects skills that deliver advantages for Juventus FC management. The result of this result shows that Juventus FC management consideration for investing the player are his skills, achievements, and market value. Then the outcomes are increasing Juventus stock, tickets and t-shirt sold out, attracting sponsors, and prize of the competition followed.
PERAN ORGANISASI REMAS DALAM MENINGKATKAN PARTISIPASI KEGIATAN KEAGAMAAN Di MASYARAKAT
Authors: Dwi Rismaningsih Okta , Suprayitno Hery , Andari Bina
Published: September 2019

This research reveals about strategy of adolescent of mosque in forming adolescent character in sub district of Babadan Sub Wlingi Blitar Regency through activities of Teens of Mosque The purpose of this research is to describe strategy of youth of mosque in forming adolescent character in sub district Babadan Sub Wlingi Kabupaen Blitar And also obstacles. The theory used in this research is adaptive strategy theory and observational social learning theory. This study uses a qualitative method. Information in this research is the board and members of the Youth Mosque. Observation techniques, interviews, and documentation is to collect data. The strategies used in the formation of religious characters through religious habituation by conducting routine religious activities is the result of research. Through habituation such as work of devotion and helping the needy citizen is forming character of adolescent strategy toward social awareness. In the formation of teenage characters mosque has a strategy through habituation greet each other and create a conducive atmosphere. The obstacles encountered are the lack of interest of adolescents to follow every activity of Teens Mosque so that needed motivation and more interesting activity again in increasing participation of social activities in society.
PENGARUH WORD OF MOUTH DAN LOKASI TERHADAP KEPUTUSAN MENGAMBIL KREDIT DI LEMBAGA PERKREDITAN DESA “MARTO NUGROHO” DESA ROWOMARTO KECAMATAN PATIANROWO KABUPATEN NGANJUK
Authors: Wihara Dhiyan Septa
Published: September 2019

Penelitian ini bertujuan untuk 1) Menganalisis pengaruh word of mouth terhadap keputusan pengambilan kredit dilembaga perkreditan desa “marto nugroho” desa rowomarto kecamatan patianrowo kabupaten nganjuk, 2) Menganalisis pengaruh lokasi terhadap keputusan pengambilan kredit dilembaga perkreditan desa “marto nugroho” desa rowomarto kecamatan patianrowo kabupaten nganjuk, 3) menganalisis word of mouth dan lokasi terhadap keputusan pengambilan kredit dilembaga perkreditan desa “marto nugroho” desa rowomarto kecamatan patianrowo kabupaten nganjuk. Populasi dalam penelitian ini adalah seluruh nasabah aktif dan non aktif lembaga perkreditan desa “marto nugroho yang berjumlah 150 orang. Jumlah sampel yang digunakan adalah 60 responden dengan teknik penentuan sampel menggunakan rumus Slovin. pengambilan data dengan menggunakan kuisioner. Teknik analisa data menggunakan analisis regresi linier berganda dengan uji t untuk menganalisis pengaruh parsial dan uji F untuk menganalisis pengaruh simultan. Berdasarkan analisis tersebut diperoleh bahwa tingkat signifikan uji F sebesar 0,000 (p<0,05), hal ini berarti word of mouth dan lokasi berpengaruh signifikan terhadap keputusan pengambilan kredit  di lembaga perkreditan desa “marto nugroho” desa rowomarto kecamatan patianrowo kabupaten nganjuk. Disisi lain berdasarkan hasil uji t dapat diketahui bahwa secara parsial word of mouth berpengaruh signifikan terhadap keputusan pengambilan kredit di lembaga perkreditan desa “marto nugroho” desa rowomarto kecamatan patianrowo kabupaten nganjukt signifikansi 0,000 (p<0,05). Sedangkan lokasi secara parsial juga berpengaruh signifikan terhadap keputusan pengambilan kredit di lembaga perkreditan desa “marto nugroho” desa rowomarto kecamatan patianrowo kabupaten nganjuk dengan nilai signifikansi uji t sebesar 0,000 (p>0,05). Variabel word of mouth lebih dominan berpengaruh karena nilai beta lebih besar dibanding variabel lokasi yaitu 0,466
Ekonomi Kerakyatan: Dari, Oleh Dan Untuk Nasionalisme
Authors: Prasetyo Wedi
Published: September 2019

Study this article aims to emphasize the importance ofdemocratic economy in an effort to confront global trade towardsnationalism. This achievement makes the spirit of awakening thepeople's welfare. The results of this study can increase the ability oflocal potential (cluster) through the development of anentrepreneurial spirit, koperasi and BUMDesa. In addition, also forthe government of the City and or district can develop a clusterstrategy in implementing the Economic Policy Net (NET). This kindof policy in order to develop the potential of the area was able to seeand develop superior power and competitiveness of products. Theresult is a formidable foster economic actors for culture and socialcapital at once in turn also "eliminate" social sorting proneconfiguration in the form of violence.
PERBEDAAN KETINGGIAN TEMPAT TERHADAP PERTAMBAHAN BOBOT BADAN KAMBING PERANAKAN ETAWA (PE) JANTAN LEPAS SAPIH
Authors: Arikustanti Nita Opi
Published: September 2019

Etawa Cross Goat (PE) is a kind of a goat. It is a cross breed between Etawa and Kacang goat. Climate, Temperature and Humidity are the important factors to increase the weight of a goat. Some kinds of goat are spread in a mountain range or plateau because the goat is like it. Problem of research is the effect of different site in increasing the weight of weaned male Etawa Cross Goat. Objective of study: To investigate the effect of different site to the weight of weaned male Etawa cross Goat. Method of study: This study is using Experimental design. It is intended to find out the effect of different site to the weight of weaned male Etawa Cross Goat. The technique of data analysis is using T-Test. The finding of study was that the t count = (0,11). Standard deviation of the goat on the plateau is and the standard deviation on the goat on lowland is. This means that there was not significant different weight of weaned male Etawa Cross goat which is live on plateau and on lowland.Key words: Etawa Cross Goat, Different Site, Animal Weight
PENAMBAHAN SARI KUNYIT (Curcuma domestic Val) TERHADAP PERTAMBAHAN BERAT BADAN DAN KONSUMSI PAKAN AYAM PETELUR JANTAN
Authors: Effendi Andri Dwi , A.K Nita Opi , Andaka Adi
Published: September 2019

It has been done a research about Curcuma Domestic Val to egg-type cockerels of hen. This research is knowing about of effect curcuma domestic val to increas weight a hen. Its used a egg-type cockerels strain Isa Brown from PT. Charoen Pokphand Indonesia more than 60 hens that old is 30 days until 58 days is ready, and curcuma domestic val that fresh juice. After 30 days old, its been done to 12 team of boxes. Every box has been 5 hens, then doing it until 1-12 agains, to 12 team of boxes assigned into 4 treatments with 3 replication. This research used experiment that completely randomized design with 4 kinds of method. According this research, can be summary that to added Curcuma Domestica Val with water can ’t real effect to in crease weight (P>0.05), with higher to P0,P1,P2,P3. That mean is 89,6, 895, 873,3, 864,3, its must to do research more than extra about to added Curcuma Domestic Val with volume more than 50 ml/1000 ml water to added weight of egg-type cockerels, so its can to know size how much ml Curcuma Domestic Val that can be responses.Keywords : Egg-type cockerels:, Body Weight, Curcuma Domestic Val