bluuebunny/crossref_metadata_2025 huggingface dataset:
Green Building Assessment and Recommendations for Optimization Case Study of the Rectorate Building the University of Lampung
Authors: Kustiani Ika , Helmi Masdar , Aini Nur Syahidah
Published: November 2023

The Green Building Concept is a concept that offers a method of managing buildings with less energy and resources utilization to minimize the environmental impact.  Since its implementation to be mandator, it is time for the University of Lampung to start implementing this concept. This research was aimed at assessing the Rectorate Building rating based on the national standard on Green Building Certification (Greenship-GBCI).  There were several steps in conducting this research.  Firstly, an opinion survey was conducted to measure the level of satisfaction of the building’s users.  Secondly, a series of measurements related to lighting, temperature, humidity, noise, and air quality were carried out.  Furthermore, an interview survey related to the operation and maintenance of the building were conducted.  Finally, all of these data were entered in the Green Building rating tool for existing buildings. The results showed that the Rectorate Building score was 23 out of 117. This score is way below the score for a bronze rating of 35. Therefore, corrective action must be taken in order the building operation management to meet the Greenship-GBCI standard.  Assessment also needs to be done on buildings througout the university for a reference in developing the University of Lampung Eco-campus program.
Mechanical property and sealing performance analysis of the diaphragm compressor cylinder head for the hydrogen refueling station under the mutation impact load
Authors: Li T. , Li M. , Zhou L. , Wang H. , Hu W. , Zhang X.
Published: November 2023

Abstract: Under the combined action of structure-process -load, the stiffness and stress distribution at the sealing interface of the ultra-high pressure diaphragm compressor cylinder head exhibit significant nonlinear and uncertain characteristics, resulting in damage to the sealing interface, diaphragm and sealing ring. This paper first establishes a finite element numerical model considering assembly process parameters based on sudden impact load conditions, and analyzes the dynamic characteristics under different assembly process parameters. It is found that some modal frequencies transition with bolt loosening. Then, the mechanical characteristics of the assembly interface of the compressor sealing system under sudden impact load were studied. The maximum equivalent stress at the assembly interface was 298.9 MPa, and the maximum deformation at the top of the air chamber was 0.167mm. Finally, the nonlinear effects of sealing ring compression rate, sealing ring diameter, and sealing groove structure on contact stress and sealing performance were obtained. The results show that as the compression ratio increases by 20% and 25%, the contact pressure at the sealing interface increases by 42.0% and 77.5%, respectively; When the compression rate is 25%, the width of the sealing groove increases by 0.5mm, and the maximum contact pressure decreases by 8.1%. The research on the dynamic characteristics and sealing performance of diaphragm compressors provides technical support for the structural optimization design of diaphragm compressors cylinder head.
O fim da metafísica e a diferença colonial
Authors: PIEPER Frederico
Published: November 2023

Este artigo busca explorar como se constituiu filosoficamente o processo de apagamento do outro na modernidade por meio da constituição do caráter autorreferenciado da modernidade. Para tanto, em um primeiro momento, segue-se a leitura que Martin Heidegger oferece da modernidade, com ênfase para a noção de que a metafísica chega ao fim por realizar todas as suas potencialidades, esgotando novas possibilidades. Em um segundo momento, indica a necessidade de se radicalizar a crítica à modernidade encampada por Heidegger, por meio da diferença colonial enquanto horizonte hermenêutico
Analisis Asbābun Nuzūl Ayat-Ayat Ekonomi Melalui Pendekatan Kontekstual
Authors: Muthmainnah Muthia , Imam Muh. Abdi , Abubakar Achmad , Ilyas Hamka
Published: November 2023

This article examines the Qur'anic verses that are nuzul embodied in economic values in it. The purpose of this study is to expose the Islamic economic values contained in these verses, and relate them to the development of the current era. There are seven economic verses that have sabab nuzul. Of the seven verses, the author categorizes them into four themes, namely related to consumption, related to distribution, related to wadiah (deposits), and related to qard (accounts receivable). The type of research applied is qualitative research with a focus on literature studies. The method of data collection and analysis is based on a normative descriptive approach that emphasizes the evaluation of the sources of data found. To strengthen the research foundation, researchers use a comprehensive and in-depth literature review approach that is in accordance with the topic discussed. The results of this study reveal that the application of economic principles contained in the Qur'an through asbabun nuzul analysis can help direct economic practices in the modern era that are fair, honest, free from usury and everything that is forbidden, and able to reduce economic inequality.Artikel ini mengkaji perihal ayat-ayat Alquran yang berasbabun nuzul yang termaktub nilai-nilai ekonomi di dalamnya. Tujuan penelitian ini untuk membeberkan nilai-nilai ekonomi Islam yang ada di dalam ayat-ayat tersebut, serta menghubungkannya dengan perkembangan zaman saat ini. Terdapat tujuh ayat-ayat ekonomi yang mempunyai sabab nuzul. Dari tujuh ayat tersebut penulis mengkategorikannya dalam empat tema yakni terkait konsumsi, terkait distribusi, terkait wadiah (titipan), serta terkait qard (utang piutang). Tipe penelitian yang diterapkan adalah penelitian kualitatif dengan fokus pada studi pustaka. Metode pengumpulan dan analisis data didasarkan pada pendekatan deskriptif normative yang menekankan evaluasi sumber-sumber data yang ditemukan. Untuk menguatkan landasan penelitian, peneliti menggunakan pendekatan tinjauan literatur yang komprehensif dan mendalam yang sesuai dengan topik yang dibahas. Hasil penelitian ini mengungkapkan bahwa penerapan prinsip-prinsip ekonomi yang terdapat dalam Alquran melalui analisis asbabun nuzul dapat membantu mengarahkan praktik ekonomi di era modern yang adil, jujur, terbebas dari riba dan segala yang diharamkan, serta mampu mengurangi kesenjangan ekonomi.
Az ökológiai lábnyom, mint összetett fogalom
Authors: Bodzsár-Urbán Éva
Published: November 2023

Az ökológiai lábnyom egy fenntarthatósági mutató, ami kifejezi, hogy mekkora a bioszférának az éves megújuló képessége. A mutató összetett, és nehezen kiszámolható, gyakran becslésekre hagyatkoznak benne. A tanulmány első sorban nem a fogalom kifejtésére irányul, sokkal inkább lehetőségeket világít meg, hogy mi minden lehetőséggel lehet tenni az ökológiai lábnyom növelése, vagy éppen csökkentése irányába. A szekunder források kiemelnek különböző országokat, és bemutatnak pozitív és negatív irányú változásokat. Összességében azt fontos kiemelni, hogy változtatni kell, mert ha az egész világ úgy élne, mint az Egyesült Államok és Európa, akkor több mint 2,6 Földre lenne szükség. Ezt pedig a Föld hosszútávon képtelen eltartani, így meg kell valósítani a legkisebb innovatív lehetőséget, bármilyen ökológiai lábnyom csökkentő intézkedést, de hosszútávon a kollektív összefogás fog pozitív változást hozni.
INEMOTION. Inteligencia emocional: Herramienta educativa para el desarrollo de competencias clave
Authors: Fernández Berrocal Pablo
Published: November 2023

El conocimiento científico del siglo 21 nos aporta los argumentos y herramientas más efectivos necesarios para educar las habilidades emocionales y sociales, tanto en la infancia como en la adultez. Por tanto, educar las emociones en Europa no es una utopía para el futuro sino una realidad que ya está ocurriendo en muchas escuelas y que necesita ser extendida al mundo adulto y profesional a través de la voluntad política y social.
Populärkultur som kunskapskälla i förskolan
Authors: Dahlström Helene
Published: November 2023

The present study examines how students in preschool teacher education perceive the role of popular culture in preschool education. By focusing on how to increase the knowledge of pre-service prescool teachers’ perceptions of popular culture in preschool, the study is an empirical contribution to early childhood literacy research. Further, the results can contribute to an understanding of how popular culture can be addressed in future preschools. The empirical data consists of focus group discussions with 67 preschool teacher students and individual interviews with seven preschool teacher students. A thematic analysis was carried out. Concepts of dimensions of literacy and funds of knowledge were used in analysis and discussion. The results reveal that participating preschool students perceived popular culture as a source of increased equity, learning, and critical literacy but also as challenging concerning equity and preschool's existing culture and value base. The main conclusion in the article is that future preschool teachers see that, together with a pedagogical idea, popular culture can be seen as a resource among others for learning and developing social competencies. However, the students did not uncritically celebrate popular culture as they highlighted the importance of preschool teachers' competencies regarding creating possibilities for critical reflections concerning popular culture that challenges democratic values.
Funeral Practice of the Sapalli Culture in the Reflection of Vedic Texts
Authors:   Samarkand State University named after Sh. Rashidov. University blv. 15, Samarkand сity, 140104, Samarkand region, Uzbekistan, Kasparov Armen R.
Published: November 2023

Northern Bactria in the Bronze Age became the arena of complex processes of interaction between the local population and the world of the Eurasian steppes. During this period, the early urban agricultural Sapalli culture, where the contacts of the two traditions were reflected not only in material but also in spiritual culture, developed and functioned on the territory of the south of modern Uzbekistan. Based on the results of studies of the burial grounds of Bustan VI–VII, the first-time attempt to verify the funeral rite with the written sources of the ancient Indo-Aryans and Indo-Iranians was made in the present work. The chosen approach made it possible to solve simultaneously several problems: to clarify the path of advancement of the Indo-Aryan tribes to India; trace one of the ideological foundations of the formation of the Bactrian civilization; illustrate the impact on the local environment of the steppe ethnos represented by the Andronovo population, identified with the Indo-Aryans. The results of the realized work allow us to speak about the significant presence of the Aryan tradition in Sapalli society and the emergence of new forms of funeral rituals. The changed mythological and ritual statements in cosmogonic representations have established as their main constant the maintenance of universal balance and order, carried out through a system of sacrifices, the highest of which at the final stage of life was a person.
Archaeological Research of the Southern Slopes of Karatau (Shimayla Complex)
Authors:   Khoja Akhmet Yassawi International Kazakh-Turkish University. B. Sattarkhanov Ave., 29B, Turkestan, 161200, Republic of Kazakhstan, Murgabayev Sagynbay S. , Bakhtybayev Mels M. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University. B. Sattarkhanov Ave., 29B, Turkestan, 161200, Republic of Kazakhstan, Maldıbekova Lazzat Dz. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University. B. Sattarkhanov Ave., 29B, Turkestan, 161200, Republic of Kazakhstan, Sizdikov Bagdaulet S. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University. B. Sattarkhanov Ave., 29B, Turkestan, 161200, Republic of Kazakhstan, Iovita, R. ,   University of Tübingen, Group Leader PALAEOSILKROAD, New York University, Associate Professor. Department of Anthropology
Published: November 2023

The authors analyze the results of the study of the archaeological complex of Shimaila. The complex includes rock carvings and a burial mound. These objects were investigated by the Karatau archaeological expedition of Ahmed Yasawi University under the leadership of S.S. Murgabayev. The research materials are being introduced into scientific discourse for the first time. The chronological framework of petroglyphs dates from the Bronze Age to the Early Middle Ages. During the excavations, three mounds were uncovered, the peculiarity of their structures was recorded, as well as the analysis of the accompanying inventory became the basis for the conclusion about the dating of burial structures within the middle of the IV century BC – II century BC. As part of the accompanying inventory, a two-edged sword, arrowheads, an earring and a pendant, a bronze mirror with a handle, a stone altar and beads. These objects, as well as the locations of petroglyphs, demonstrate the prospects for further field studies of Karatau monuments for the reconstruction of complex processes of cultural genesis in the Central Asian region from the Bronze Age to the turn of our era.
Bioarchaeology and Paleoclimate Aspects of the Study of the Upper Don Region Population of the Middle Bronze Age
Authors:   N. N. Miklukho-Maklai Institute of Ethnology and Anthropology, Russian Academy of Sciences. Leninsky prospect, 32А, Moscow, 119334, Russian Federation, Vasilyev Sergey V. , Borutskaya Svetlana B. ,   M.V. Lomonosov Moscow State University. Leninskiye Gory, 1, build.12, Moscow, 119991, Russian Federation, Puzanova Tatyana A. ,   M.V. Lomonosov Moscow State University Department of Geography Chair of Landscape Geo/chemistry and Soil Geography. Leninskiye Gory, 1, Moscow, 119234, Russian Federation, Zheludkov Andrey S. ,   Lipetsk Regional Scientific Public Organization «Archaeological Research». Kommunalnaya square, 9, Lipetsk, Russian Federation, Chendev Yury G. ,   Belgorod State National Research University, Institute of Earth Sciences. Pobedy str., 85, Belgorod, 308015, Russian Federation, Burova Natalya D. ,   Institute for the History of Material Culture. Dvortsovaya embankment, 18A, 191186, St. Petersburg, Russian Federation, Lokhova Olga V. ,   Institute for the History of Material Culture, Russian Academy of Sciences. Dvortsovaya embankment, 18A, 191186, St. Petersburg, Russian Federation
Published: November 2023

The paper presents the reconstruction of the lifestyle, environment, and climate conditions of the inhabitants of the forest-steppe zone of the East European Plain in the Middle Bronze Age. Presented study is based on the results of archaeological work on the territory of the archaeological heritage site «Volkhonskiye Vyselki 1, kurgan» carried out in 2021 by the expedition of the Lipetsk regional scientific public organization «Archaeological Research». The mound belongs to the Middle Don Catacomb culture and contains 9 graves. It was demonstrated that the climate at the time of the creation of the mound were more arid than at modern times by soil-archaeological method. Levels of mobile P forms in soils suggest that the site was used for feasts, both before the creation of the mound and after. The gender and age, osteometric and pathological characteristics of the skeletons of 15 buried are given. Because of the results of isotope analyzes it has been assumed that the diet of the deceased was based on plant food.
Typological Analysis and Assessment of the Bone-Working Stone Inventory of the Zamostje 2 Late Mesolithic Layer
Authors:   Institute for the History of Material Culture, Russian Academy of Sciences. Dvortsovaya emb., 18, St.-Petersburg, 191186, Russian Federation, Lozovskaya Olga V. , Fedorova Daria N. ,   Institute for the History of Material Culture, Russian Academy of Sciences. Dvortsovaya emb., 18, St.-Petersburg, 191186, Russian Federation, Malyutina Anna А. ,   Institute for the History of Material Culture, Russian Academy of Sciences. Dvortsovaya emb., 18, St.-Petersburg, 191186, Russian Federation, Taktasheva Snezhana D. ,   St.Petersburg State University, Mendeleyevskaya linia, 5, Saint Petersburg, 199034, Russian Federation; Institute for the History of Material Culture, Russian Academy of Sciences. Dvortsovaya emb., 18, St.-Petersburg, 191186, Russian Federation
Published: November 2023

The article presents the results of a typological and functional analysis of flint assemblage from the Late Mesolithic layer (II half of the 7th – early 6th millennium cal BC) at the site Zamostje 2 (Volga-Oka region). The studied series of flint implements is limited to a material from the excavations of 1996–97 and has 11892 artefacts. A typological analysis of the Late Mesolithic flint industry at Zamostje 2 showed the absence of standard blanks and the instability of tool morphology. The shaping of tools was due to the needs of production operations for hard materials. In order to reconstruct the features of bone production in the Late Mesolithic on the East European Plain, the collection was evaluated and 193 items were selected for use-wear analysis. The results of the experimental and traceological analysis revealed 24 tools with microtraces of bone processing, among which scrapers predominate. In a small number there are tools for sawing-cutting and burin cutting (grooves and engravings). A flint polished adze was used to chop a bone or elk antler. The identified implements for working bone (antler), on the one hand, showed a certain homogeneity of morphological characteristics and modes of shaping the working blades of the tools, on the other hand, gave a clear idea of the methods of processing solid organic raw materials in the Late Mesolithic period.
Stone Decorations from the Chalcolithic Sites of the Upper and Middle Kama Region (an attempt at complex analysis)
Authors:   Perm State University, Bukireva str., 15, Perm, 614990, Russian Federation, Lychagina Evgenia L. ,   Perm State Humanitarian Pedagogical University. Sibirskaya St., 24, Perm, 614990, Russian Federation, Smertina Anastasia Yu. ,   Perm State University, Bukireva str., 15, Perm, 614990, Russian Federation; Perm State Humanitarian Pedagogical University. Sibirskaya St., 24, Perm, 614990, Russian Federation, Tomilina Elena M. ,   Perm State University, Bukireva str, 15, Perm, 614990, Russian Federation
Published: November 2023

The purpose of the article was a comprehensive study of stone decorations from the Chalcolithic sites of the region. The authors used petrographic description, typological and use-wear analysis. The authors examined 40 items from 6 archaeological sites located in the Upper (2) and Middle (4) Kama region. The jewelry was made of serpentinite of varying degrees of hardness. Serpentinite could originate from the Saranovsky and Moivinsky deposits in the Perm region. The shape of the products was divided into 5 groups, among which the leading ones were oval and teardrop-shaped. Most of the jewelry had a single through hole, which was more often located in the upper part of the product and was drilled on one side. The use-wear analysis made it possible to identify traces from the manufacture of jewelry, traces from use and traces that appeared as a result of the archeologization of objects. Most products were treated as patches on clothing. The shape and quality of jewelry could depend on both the hardness of the raw materials and the skills of the master. They don't create standard groups. The closest analogies can be found in the ornaments studied at the Ust-Kama burial grounds. The population that left these burial grounds could take part in the formation of the Chalcolithic cultures of the Kama forest.
A New Neolithic Site in the Nothern Caspian Region
Authors:   Samara State University of Social Sciences and Education. Maxim Gorky St. 65/67, 443099, Samara, Russian Federation, Doga Natalya S. , Vybornov Alexander A. ,   Samara State University of Social Sciences and Education. Maxim Gorky St. 65/67, 443099, Samara, Russian Federation, Gilyazov Filat F. ,   Samara State University of Social Sciences and Education. Maxim Gorky St. 65/67, 443099, Samara, Russian Federation, Somov Anatoly V. ,   Samara State University of Social Sciences and Education. Maxim Gorky St. 65/67, 443099, Samara, Russian Federation, Grechkina Tatiana Yu. ,   ASU of the Astrakhan region «Scientific and Production Institution «Heritage». Krasnaya Embankment str., 24, Astrakhan, 414000, Russian Federation
Published: November 2023

Tuskuduk site’s materials from the North Caspian Sea region are published in an article. A goal of this work is characteristics of material culture’s remains, which were found as a result of excavation of 2022 year. The tasks of research include: description of the site, ceramics and stone inventory, their cultural attribution and determination of the place within the Neolithic of this region. During the research of the site, spatial, typological, statistical, archeozoological and radiocarbon methods were used. The nature of the cultural layer distribution was determined on the results of spatial analysis. The typological analysis made it possible to identify the features typical in ceramics and stone artifacts, to establish their characteristics in comparison with other complexes within the area of the interest. The archeozoological method contributed to the determination of the species composition of animals. Radiocarbon analysis specified the absolute age of the site. Based on the analysis of materials from the Taskuduk site, the presence of a preserved cultural layer was established. Ceramic and stone inventory belong to the Tenteksor cultural type of the Late Neolithic period. The specificity of the design of the upper parts of the vessels is revealed. Polished and drilled items were identified among the stone tools. Animal bones belong to wild species. The complex dates to 6700–6500 BP on radiocarbon determinations.
Environmental and Cultural Transformations at the Turn of the Late Bronze and Early Iron Age in the Steppe Belt of Eurasia
Authors:   Herzen State Pedagogical University, Moyka River, 48/12 emb, St. Petersburg, 191186, Russian Federation, Kulkova Marianna A.
Published: November 2023

At the turn of the Late Bronze and Early Iron Age in the steppe belt of Eurasia there were significant cultural transformations which probably had been connected with Rapid Climatic Cycles (RCC) in this time, around 3,2 ka calBP. The correlation of data obtained on the base of radiocarbon dating, paleoclimatic reconstructions and cultural and historical chronology for eastern and western zones of the Great Steppe allowed us to reconstruct these processes. In the Late Bronze period bearers of the Кarasuk culture spread in the steppe zone of the Southern Siberia from Central Kazakhstan to Mongolia and Northern Chine. Formation of the Late Bronze Age cultures Sabatinovka and Belozerka Active cultures took place during period of favorable environment. Then the bearers of the early Hallstattian Carpathian-Danubian cultures and the Cimmerian nomads appeared in the beginning of the Early Iron Age during the aridization episode. Since the middle of 9th century BC expansion of the nomadic Scythian cultures within the whole steppe belt began because of wet climatic conditions.
Evaluation of the Technological Properties of Artificial Agglomerated Stones in Epoxy Resin and Castor Oil-Based Vegetable Polyurethane Matrix
Authors: Castilho Evanizis Dias Frizzera , Sant'Ana Maria Angelica Kramer , Teixeira Dullye Noleto Lima , Silva Maria Eduarda Delabeneta , Gadioli Mônica Castoldi Borlini
Published: November 2023

Objective: The aim of this study was to produce and evaluate the technological properties of artificial agglomerated stone slabs produced using the waste from the stone commercially known as "Preto São Gabriel," using epoxy resin and castor oil-based polyurethane.
 
Theoretical framework: Ornamental stones are widely used in the construction sector and are of great economic importance to the country. During the production stages, a significant amount of waste is generated. The production process generates a substantial amount of waste from the extraction and processing processes that have no economic value, accounting for approximately 40 to 60% of the production during mining, and during the cutting stage, about 30 to 35% is generated.
 
Method: To manufacture the artificial stone slabs, the waste was crushed in a jaw crusher and ceramic plate mill and screened into three particle size ranges. The slabs were produced using the vacuum vibro-compression method. Technological characterization tests were conducted, including bulk density, apparent porosity, water absorption, and three-point strength tests.
 
Results and conclusions: It is concluded that slabs produced with both resins can be applied in locations requiring good flexural strength. For use in areas with water presence, those produced with epoxy resin are recommended, as they exhibited lower porosity and water absorption.
 
Research implications: Utilizing waste from ornamental stones, which amounts to millions of tons and is disposed of in landfills or storage facilities, to manufacture agglomerated stones represents a significant contribution to environmental impact reduction, aligning with the principles of ESG (Environmental, Social, and Corporate Governance).
 
Originality/value: The evaluation of the technological properties of artificial agglomerated stones produced from ornamental stone waste is of fundamental importance for the correct and safe application of these sustainable materials in civil construction.
Diagnosis and Obstacles Related to the Production Chain of Cachaça in the Context of Geographical Indications
Authors: Saldanha Cleiton Braga , Silva Daliane Teixeira , Martins Luís Oscar Silva , Silva Marcelo Santana
Published: November 2023

Objective: To analyze regulatory and public policy, economic, agronomic, infrastructure, and technological barriers in the context of Geographical Indications.
 
Method: This study was carried out from the perspective of exploratory research since it is a conceptual approach, which investigates the main characteristics of the studied phenomenon. Considering the way in which the data were obtained, it consists of a bibliographical study of a qualitative nature, which has the cachaça productive chain as its central element.
 
Results and conclusion: It is observed that the foundation of the GI is based on the relationship between natural resources, the organization of social and economic processes, and cultural and power relations. The obstacles highlighted from the point of view of specialists directly affect the development process of the cachaça production chain, but it is a historically important activity for Brazil.
 
Research implications: They range from direct support to the cachaça industry and the formulation of public policies to the advancement of academic knowledge and the strengthening of regional culture and economy. It contributes to multiple aspects of society, highlighting the relevance of Geographical Indications.
 
Originality/value: The identification of critical obstacles in the cachaça production chain, deepening the understanding of the complex relationship between natural resources, culture, and social and economic processes in the formation of Geographical Indications (GIs) in Brazil fills an important gap in the context of the growing recognition of GIs in Brazil.
DIVERSITY OF MYCORRHIZAL FUNGI IN THE RHIZOSPHERE OF Avicennia officinalis (L.) IN THE PENITI MANGROVE FOREST, MEMPAWAH REGENCY
Authors: Linda Riza , Rafdinal Rafdinal
Published: November 2023

Mycorrhizal fungi are a form of mutualistic symbiosis between fungi and plant roots, including mangrove api-api that grows on mangrove area. This study aims to determine the diversity of mycorrhizal fungi on mangrove api-api (Avicennia officinalis L.) This study used a combination of wet filtering and centrifugation techniques for spore isolation. The results showed that the types of mycorrhizal fungi found in mangrove area were Scutellospora, Gigaspora, Acaulospora Glomus sp1, Glomus sp2, Glomus sp3 and Glomus sp4. The diversity of mycorrhizal fungi in Peniti area was 0,07105 and Sungai Purun was 0,47280. the distribution of species is uneven, there are species that dominate and conditions are unstable. Spore density of 103 spores /100 gr soil and level of root infection percentage with low class (class 1) was 0,24% in Peniti dan 0,18 % in Purun River.
ENGAGING STUDENTS IN A FLIPPED CLASSROOM INSTRUCTION: TEACHING ENGLISH FOR SPECIFIC PURPOSE (ESP) IN HIGHER EDUCATION
Authors: Al Baekani Abdul Kodir , Hapsari Nesti , Muslihat Asep
Published: November 2023

ESP (English for Specific Purpose) is part of ELT (English Language Teaching) which contains the teaching of English as a foreign language. Every English teacher, especially ESP, must innovate in the delivery of their teaching materials which are always carried out from year to year. This study reports on the perceptions of economics major students about the use of flipped classroom models in learning English for Specific Purpose (ESP). Illustrated in classroom action research through reflective journals, photo elicitation and interviews data. Qualitative findings show that: 1) all students enjoy watching video teaching materials and have an interest in using them to learn English; 2) the use of flipped classroom in learning English makes students independent and active in learning English; 3) flipped classroom engaged students in learning English in different contexts of discourse; 4) flipped classroom mode motivated students in learning English. The findings of this study are expected to be useful for other researchers interested in EFL learning innovations or teachers who are looking for teaching English for Specific Purpose (ESP).
NMR ANALYSIS OF LPRDA PEPTIDE, AN INHIBITOR OF STAPHYLOCOCCUS AUREUS SORTASE A
Authors:   Kazan Scientific Center RAS, Kuchaev E.S. , Kudryavcev K.V. , Klochkov V.V. , Aganov A.V. , Usachev K.S. ,   Pirogov Russian National Research Medical University, Moscow,   Kazan Federal University
Published: November 2023

The enzyme Sortase A (SrtA) anchors surface proteins and adhesins responsible for virulence on the cell wall and appears to be a potential target for the control of pathogenic bacteria. In the framework of this work, the structure in solution of the oligopeptide LPRDA, which is a promising basis for the development of peptidomimetics inhibiting Sortase A, was analysed by NMR spectroscopy.
THE USE OF BACTERIAL MOTILITY CHARACTERISTICS FOR RAPID ASSESSMENT OF ANTIBIOTIC SENSITIVITY
Authors:   Joint Institute of High Temperatures RAS, Moscow, Litvinenko V.V. , Vasilieva E.V. , Abdulkadieva M.A. , Sysolyatina E.V. , Ermolaeva S.A. ,   Gamaleya National Research Center for Epidemiology and Microbiology, Moscow
Published: November 2023

Motile bacteria are capable of converting chemical energy into directed movement. The characteristics of motility (trajectories, average speeds, average time spent in a layer, etc.) depend on the morphology of the bacterial cell (number and arrangement of flagella), the presence of chemical stimuli in the environment, distance from the surface, and bacterial concentration. Changes in motility parameters can be used as a prognostic indicator of bacterial cell metabolism disorders.
THE THERMOSTABILITY ENHANCEMENT OF RENILLA MUELLERI RECOMBINANT LUCIFERASE
Authors:   Siberian Federal University, Krasnoyarsk, Nur S.A. , Larionova M.D. , Burakova L.P. , Eremeeva E.V. ,   Institute of Biophysics SB RAS, Krasnoyarsk
Published: November 2023

The use of luciferase as bioluminescent markers is often complicated by a significant decrease in enzymatic activity at physiological temperatures. To increase the thermal stability of RmY luciferase, a number of amino acid substitutions were introduced into the corresponding genetic construct by site-directed mutagenesis. The thermal stability of RmY luciferase was shown to increase in response to the introduction of selected amino acid substitutions.
The life path and scientific works of Academician V.K. Kulagina
Authors: Цыган В.Н. , Мамаева С.А.
Published: November 2023

Статья посвящена анализу массива научных публикаций выдающегося патофизиолога академика Виктора Константиновича Кулагина. Цель сообщения – раскрыть и подчеркнуть вклад В.К. Кулагина в разработку учения о травме и шоке. Анализ показал, что основными аспектами экспериментальных исследований ученого были нейрогуморальные механизмы развития травматического шока, различия травматического шока и шока при кровопотере, роль нарушений функций эндокринной системы (гипофиз, кора надпочечников) и значение изменений ряда ферментных систем в патогенезе шока. Кулагин разработал методы ранней профилактики и принципы лечения шока и кровопотери с использованием крови, кровезаменителей, адренокортикотропного гормона, кортикостероидов и некоторых ферментов. Результаты проведенных им исследований позволили создать целостную патогенетически обоснованную картину шока. Кулагин вплотную подошел к решению проблемы ранней профилактики шока, стоял у истоков концепции травматической болезни.

The purpose of the article is based on the analysis of the array of scientific publications of the outstanding pathophysiologist, academician V.K. Kulagina to reveal his contribution to the development of the doctrine of trauma and shock. The analysis showed that the main aspects of the scientist’s experimental studies were the neurohumoral mechanisms of the development of traumatic shock, the differences between traumatic shock and blood loss, the role of dysfunctions of the endocrine system (pituitary gland, adrenal cortex), the significance of changes in a number of enzymatic systems in the pathogenesis of shock. Kulagin developed methods for early prevention and principles for the treatment of shock and blood loss using blood, blood substitutes, adrenocorticotropic hormone, corticosteroids, and certain enzymes. The results of his studies made it possible to create a holistic pathological picture of shock. Kulagin came close to solving the problem of early prevention of shock, stood at the origins of the concept of traumatic disease.
Fluorescence of the retinal chromophore in microbial and animal rhodopsins
Authors: Nikolaev Dmitrii M. , Shtyrov Andrey A. , Vyazmin Sergey Yu. , Vasin Andrey V. , Panov Maxim S. , Ryazantsev Mikhail N.
Published: November 2023

Fluorescence of the vast majority of natural opsin-based photoactive proteins is extremely low in accordance with their functions that depend on efficient transduction of absorbed light energy. However, recently proposed several classes of engineered rhodopsins with enhanced fluorescence along with the discovery of a new natural highly fluorescent rhodopsin, NeoR, opened a way to exploit these transmembrane proteins as fluorescent sensors and draw more attention to studies on this untypical rhodopsins property. Here we review available data on the fluorescence of the retinal chromophore in microbial and animal rhodopsins and their photocycle intermediates as well as different isomers of the protonated retinal Schiff base in different solvents and the gas phase.
Chemical space exploration with Molpher: Generating and assessing a glucocorticoid receptor ligand library
Authors: Agea Maria Isabel , Čmelo Ivan , Dehaen Wim , Šícho Martin , Chen Ya , Kirchmair Johannes , Sedlák David , Bartůněk Petr , Svozil Daniel
Published: November 2023

Computational exploration of chemical space is important in modern cheminformatics research as it can accelerate the discovery of new biologically active compounds. In this study, we present a detailed analysis of a chemical library generated by one of the available molecular generators, Molpher. A targeted library of potential glucocorticoid receptor (GR) ligands was generated, and its composition was compared with a reference library randomly sampling chemical space. A random forest was used to determine the biological activity of ligands, and its applicability domain, which is essential to consider when predicting the biological activity of newly designed compounds, was incorporated using conformal prediction. It was demonstrated that the GR ligand library is significantly enriched with GR ligands compared to the random library. Moreover, through prospective analysis, it was shown that Molpher could design compounds that were later experimentally verified as active on the GR. Finally, a set of 34 potential GR ligands was proposed.
Process Intensification of the Continuous Synthesis of Bio-derived Monomers for Sustainable Coatings using a Taylor Vortex Flow Reactor
Authors: Edwards Matthew D. , Pratley Matthew T. , Gordon Charles M. , Teixeira Rodolfo I. , Ali Hamza , Mahmood Irfhan , Lester Reece , Love Ashley , Hermens Johannes G. H. , Freese Thomas , Feringa Ben L. , Poliakoff Martyn , George Michael W.
Published: November 2023

We describe the optimization and scale-up of two consecutive reaction steps in the synthesis of bio-derived alkoxybutenolide monomers that have been reported as potential replacements for acrylate-based coatings (Sci. Adv., 2020, 6, eabe0026). These monomers are synthesized by (i) oxidation of furfural with photo-generated singlet oxygen followed by (ii) thermal condensation of the desired 5-hydroxyfuranone intermediate product with an alcohol, a step which until now has involved a lengthy batch reaction. The two steps have been successfully telescoped into a single kilogram-scale process without any need to isolate the 5-hydroxyfuranone between the steps. Our process development involved FTIR reaction monitoring, FTIR data analysis via 2D-visualization and two different photo-reactors (i) a semi-continuous photo-reactor based on a modified rotary evaporator where FTIR and 2D-correlation spectroscopy (2D-COS) revealed the loss of the methyl formate co-product and (ii) our fully continuous Taylor Vortex photo-reactor which enhanced the mass transfer and permitted the use of near-stoichiometric equivalents of O2. The use of inline FTIR monitoring and modelling greatly accelerated process optimization in the Vortex reactor. This led to scale up of the photo-oxidation with an 85% yield and a projected productivity of 1.3 kg day-1, with a space time yield of 0.06 mol day-1 mL-1. Higher productivities could be achieved whilst sacrificing yield; e.g. 4 kg day-1 at 40% yield. The second step, the thermal condensation of 5-hydroxyfuranone, was transformed from a 20 h batch reflux reaction to a < 1 minute thermal flow reaction in a reactor only 3 mL in volume operating at 200 oC with projected productivities of >700 g day-1. Proof of concept for telescoping the two steps was established with an overall two-step yield of 67%, producing a process with projected productivity of 1.1 kg day-1 of the methoxybutenolide monomer without any purification of the 5-hydroxyfuranone intermediate.
Sodium Energy Storage-Key Clean Energy for the Future World
Authors: Tan Dazhi , Chen tongtong , Zhang Zhitong , Fan Wenjie
Published: November 2023

In order to address the energy and environmental crises resulting from the extensive use of fossil fuels, countries worldwide are actively developing renewable energy sources such as solar and wind power. One crucial link in achieving the large-scale, efficient utilization of renewable energy is energy storage. This paper proposes a new energy utilization scheme based on sodium, analyzes the characteristics of sodium-water reactions, and designs an energy release device for sodium in water vapor combustion. Compared to existing energy storage technologies, sodium-based solutions offer advantages like improved safety, higher energy density, lower operating costs, and faster startup and shutdown speeds. This ensures the reliable integration of large-scale renewable energy generation into the power grid, fundamentally transforming traditional energy supply models and achieve decoupling of final energy consumption and carbon emissions.
Bicyclo[m.n.k]alkane Building Blocks as Promising Benzene and Cycloalkane Isosteres: Multigram Synthesis, Physicochemical and Structural Characterization
Authors: Semeno Volodymyr , Vasylchenko Vadym , Fesun Ihor , Ruzhylo Liudmyla , Kipriianov Mykhailo , Melnykov Kostiantyn , Skreminskyi Artem , Iminov Rustam , Vashchenko Bohdan , Grygorenko Oleksandr
Published: November 2023

Electrophilic double bond functionalization – intramolecular enolate alkylation sequence was used to obtain a series of bridged and fused bicyclo[m.n.k]alkane derivatives (i.e., bicyclo[4.1.1]octanes, bicyclo[2.2.1]heptanes, bicyclo[3.2.1]octanes, bicyclo[3.1.0]hexanes, and bicyclo[4.2.0]heptanes). The scope and limitations of the method were established, and applicability to the multigram synthesis of target bicyclic compounds was illustrated. Using the developed protocols, over 50 mono- and bifunctional building blocks relevant to medicinal chemistry were prepared. The synthesized compounds are promising isosteres of benzene and cycloalkane rings, which is confirmed by their physicochemical and structural characterization (pKa, LogP, and exit vector parameters (EVP)). Rules of thumb for the upcoming isosteric replacement studies were proposed.
Zwitterionic Acridinium Amidate: A Nitrogen-Centered Radical Catalyst for Photoinduced Direct Hydrogen Atom Transfer
Authors: Entgelmeier Lukas , Mori Soichiro , Sendo Shion , Yamaguchi Rie , Suzuki Ryuhei , Yanai Takeshi , Mancheño Olga , Ohmatsu Kohsuke , Ooi Takashi
Published: November 2023

The development of small organic molecules that can convert light energy into chemical energy to directly promote molecular transformation is of fundamental importance in chemical science. Herein, we report a zwitterionic acridinium amidate as a catalyst for the photoinduced direct functionalization of aliphatic C–H bonds. This organic zwitterion absorbs visible light to generate the corresponding amidyl radical in the form of excited-state triplet diradical with prominent reactivity for hydrogen atom transfer to facilitate C–H alkylation with a high turnover number. The experimental and theoretical investigations revealed that the noncovalent interactions between the anionic amidate nitrogen and a pertinent hydrogen-bond donor are crucial for ensuring the efficient generation of catalytically active species, thereby fully eliciting the distinct reactivity of the acridinium amidate as a photoinduced direct hydrogen atom transfer catalyst. The broad utility of the acridinium amidate was further demonstrated through hybrid catalysis with transition-metal complexes for acceptorless dehydrogenations.
Modeling Gas Adsorption and Mechanistic Insights into Flexibility in Isoreticular Metal–Organic Frameworks using High-Dimensional Neural Network Potentials
Authors: Tayfuroglu Omer , Zorlu Yunus , Kocak Abdulkadir
Published: November 2023

Metal–organic frameworks (MOFs), known for their remarkable porous and well-organized structures, have found extensive use in various applications including gas storage. Predicting the bulk properties from atomistic simulations as well as gas uptakes and adsorption mechanism requires the most accurate definition of MOF systems. The application of ab initio molecular dynamics to these extensive periodic systems exceeds current computational capabilities. Consequently, alternative strategies need to be devised to lower computational costs without compromising accuracy. In this work, we construct high dimensional neural network potentials (HDNNP) to describe rotationally and translationally invariant energies and forces of isoreticular metal organic framework (IRMOF) series at the DFT level of accuracy using the fragmentation technique so as to study H2 and CH4 adsorption isotherms considering the flexibility of MOFs during gas adsorption by means of “adsorption relaxation” model in which MD and GCMC simulations were performed simultaneously. Our results showed that classical simulations may diverge from experiments due to the failure of the force field when accounting for flexibility in MOFs whereas our HDNNP follows a much better trend to experimental values. Moreover, we show that the real number of CH4 uptake values of IRMOF-10 can be much more than what classical force field predicts. In addition, adsorption relaxation simulations enable us to characterize behavior of MOF atoms and distribution of gas molecules during the adsorption process, giving the most detailed mechanistic picture.
A Review of Apoptosis and Neuronal Differentiation
Authors: G Rajeswari , Chakra R Gautham , P Jahnavi , Kumar R M Praveen Prem , K Chandhrashekar
Published: November 2023

Nearly all neurocognitive diseases have been polypeptide homeostatic illnesses, as caused by abnormal tabulates racking up. That whole neurodegenerative operation was indeed mediated whilst also various metabolism processes, some of which cause apoptotic cell death. Presently, hydrophilic biliary acids, especially TUDCA, commonly called tauroursodeoxycholic acids, are all seen as meaningful anti- apoptotic but instead neuroprotective events, to innovative but instead clinical information proposing with their therapeutic potential use disease-modifiers out neurodegenerative diseases. Neurite outgrowth has been a predominantly critical ingredient of about assemble positive neuronal networks. Sirt1-7 were indeed distinctive homologs even before sirtuins. Those who play a major part throughout many attributes like biological but also restrict crucial peptides. Modulation of sirtuins can again be implemented as either a treatment option or just for metabolic disorders. Neurological conditions have different clinical manifestations and are largely at the maturity level as well as leading to loss of nutrient homeostasis.
Four paths to social wellbeing
Authors: Živko Bergant
Published: November 2023

Several definitions of social welfare can be found in the professional literature, especially on corporate social responsibility. In this paper, we start from the social responsibility of corporates and individuals for the creation of added value as a fundamental criterion for defining appropriate behavior. At the same time social irresponsibility is defined as well. It is important to define the responsible pillars for particular processes. Such a definition of processes enables the planning of social action in the broadest sense.
Cooperatives and the capabilities of the poor
Authors: Diego Lanzi
Published: November 2023

The paper reviews main theoretical reasons explaining why cooperatives and cooperation in developing, rural and poor countries, have a comparative advantage in enlarging poor people's capabilities. In particular, we consider main pillars of the Capability Approach to human development with reference to the relation between groups and capabilities, and discuss why cooperative groups can support participatory human development, grassroots empowerment and human poverty alleviation.