bluuebunny/crossref_metadata_2025 huggingface dataset:
Expression of bovine leukaemia virus (BLV) gp51 protein in blood and milk cells of cows with leukosis
Authors: Szczotka Maria , Kuźmak Jacek
Published: August 2022

Introduction

Bovine leukaemia virus (BLV) is the retroviral causative agent of enzootic bovine leukosis, the most common neoplastic disease of cattle and a serious problem worldwide. Its diagnosis is commonly by tests for antibodies recognising the p24 capsid protein and structural glycoprotein (gp) 51. With flow cytometry recently having come to veterinary immunology, applications for it may now include BLV. The study determined BLV gp51 expression in blood and milk lymphocytes of naturally infected cows by flow cytometry.

Material and Methods

Nineteen Polish Black and White Lowland breed cows aged 4–9 years and naturally infected with BLV and ten uninfected counterparts had blood and milk sampled and cultured. The immunological status of the animals was confirmed with ELISA and PCR. Dual-colour flow cytometry analysis was performed with specific monoclonal antibodies for lymphocyte cluster of differentiation (CD) markers and gp51 viral envelope protein and conjugates labelled with fluorescein isothiocyanate or phycoerythrin. Bovine leukaemia virus gp51 was confirmed in lymphocytes by immunofluorescence with anti-gp51 monoclonal antibodies.

Results

The gp51 antigen was detected in blood and milk lymphocytes of infected cows, but the percentage of cells expressing it in milk was much lower than in blood. A depleted number of CD4+ lymphocytes, an augmented number of CD8+ lymphocytes, a lower ratio of CD4+ to CD8+ and a proliferation of CD19+ immunoglobulin M+ cells were also found.

Conclusion

These proliferated cells were immature, gave no sign of a tendency to differentiation and were characterised by prolonged vitality.
Is serological monitoring a fit-for-purpose tool to assess the epidemiological situation of tuberculosis in the sylvatic species of European bison (Bison bonasus) in Poland?
Authors: Krzysiak Michał K. , Larska Magdalena , Zabost Anna , Didkowska Anna , Krajewska-Wędzina Monika , Anusz Krzysztof , Augustynowicz-Kopeć Ewa
Published: August 2022

Introduction

Bovine tuberculosis is one of the most dangerous zoonotic diseases. Despite the near-complete elimination of the disease from cattle breeding in Poland achieved in 2009, its re-emergence is now observed. Globally, the number of human cases is underestimated and the importance of free-living animals as reservoirs of tuberculosis is growing. As a species highly susceptible to Mycobacterium tuberculosis complex infection, the European bison (Bison bonasus) has a role in the transmission of the disease in Poland. The purpose of the investigation was to assess the epidemiological situation of tuberculosis in Polish European bison serologically.

Material and Methods

A total of 460 serum samples were collected from 436 European bison from 15 out of 26 national populations between 2013 and 2020. An M. bovis ELISA was used, and its sensitivity and specificity were assessed with an eyelid tuberculin skin test (TST) and interferon gamma release assay (IGRA).

Results

Mycobacterium bovis antibodies were detected in nine serum samples. The presence of antibodies was found in two animals from the Białowieża Forest (1.2% of the population), and one each from the Borecka Forest (2.4%) and the Warsaw Zoo (14.3%). One European bison among the 14 sampled (7.1%) from Smardzewice was positive on five occasions. Other samples from Smardzewice and the Bieszczady Mountains, where tuberculosis had previously been reported, were negative.

Conclusion

ELISA testing is an effective, easy and cost-efficient tool for monitoring of tuberculosis-naïve populations. Serological testing in tuberculosis control programmes can significantly improve the detection of infected herds. Antibody ELISAs may supplement TST and IGRA, but cannot replace them.
Israel’s changing geostrategic posture
Authors: Eiran Ehud
Published: August 2022

This paper analyzes Israel’s changing understanding of its geostrategic posture from its establishment in 1948 to the current era. It starts by reviewing traditional Israeli geostrategic ideas and their implementation, mostly, as reflected in the nation’s national security doctrine. The paper then investigates the effect of Israel’s territorial expansion after 1967 on Israeli ideas about geostrategy. Finally, the paper shows how changing global, regional, and technological variables in the last two decades have transformed how Israeli elites understand their geostrategic realities and how they allocate resources in response to these changing conditions.
Monterrey y su Día Cero
Authors:   Instituto Mexicano de Tecnología del Agua - IMTA, Breña Naranjo Agustín
Published: August 2022

Hace poco más de 4 años, Ciudad del Cabo, una de las ciudades más importantes del continente africano sufrió su mayor crisis hídrica, también conocida como el Día Cero (en referencia al día en el cual la ciudad estaría imposibilitada para abastecer de agua a su población), como consecuencia de un déficit de precipitación acumulado a lo largo de 3 años.
The Use of Balanced Scorecard to Support Achievement of Business Plan in Digestive Endoscopy Center, 2013
Authors: Abdullah Murdani , Makmun Dadang , Fauzi Achmad , Santi Aan
Published: August 2022

Background: Digestive Endoscopy Center, Cipto Mangunkusumo Hospital was established in 2011 in which the concept was developed as center of excellence (CoE). The business plan was created based on safety and patient satisfaction, fast, accurate, quality and one stop services. 2013 is the 2nd year in Digestive Endoscopy Center business plan development and it is expected to increase in many aspects. The aim of this study is to measure the performance of business plan in Digestive Endoscopy Center.Method: This study was conducted from April-December 2013 with quantitative method and cross sectional studies on 76 subjects and also used secondary data from endoscopy’s reports. The balanced scorecard contains 4 measurements, such as financial approach, customer approach, internal process approach, and learning and growth approach. Results: The financial approach resulted that income from 2 types of patients (cash and insurance) were increased in 2013. The customer approach resulted a high satisfaction rate with mean 4.69 of 5 for patient satisfaction and the employee satisfaction increased in 2013 (mean: 3.88 of 5) and in 2010 (mean: 3.64 of 5). Internal process approach was measured using facilities and infrastructure discovered is increased too. Learning and growth approach resulted that accumulation of trainings, achievement of target of the trainings was increased.Conclusion: The achievement of bussiness plan has been evaluated using balanced scored card and showed that there is a balance on the financial approach, customer approach, internal process approach, and learning and growth approach.Keywords: business plan, digestive endoscopy center, balance scorecard
MORPHOLOGICAL PATTERNS OF DEVELOPMENT AND PREVENTION OF EXPERIMENTAL EPIDURAL FIBROSIS
Authors:   Irkutsk Scientific Center of Surgery and Traumatology, Irkutsk, Russian Federation, SHURYGINA I.A. , ZHIVOTENKO A.P. ,   Irkutsk Scientific Center of Surgery and Traumatology, Irkutsk, Russian Federation, GOLDBERG O.A. ,   Irkutsk Scientific Center of Surgery and Traumatology, Irkutsk, Russian Federation, SOROKOVIKOV V.A. ,   Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuing Professional Education, Irkutsk, Russian Federation
Published: August 2022

Objective: To identify the morphological patterns of development and prevention of experimental epidural fibrosis based on the shape of the dural sac in the area of laminectomy. Methods: Male Wistar rats aged 4-5 months underwent laminectomy at the level of L6-S1. The animals were divided into two groups with 7 animals per group. In the main group (Group A) the animals were treated with Antiadhesin® gel applied to the wound to prevent the development of epidural fibrosis, while in the group of comparison (Group B), the gel was not applied. Another 7 healthy animals were used as a control group. The animals were taken out of experiment on the 28th day. Histological slides stained with hematoxylin-eosin were used to measure the width and length of the dural sac, its area, perimeter, and calculate its deformity index. Results: In group B at the level of laminectomy, the ratio of the width to length of the dural sac was significantly higher than in the control group (p<0.05), mainly due to the enlarged width, while the length did not change significantly. In group A these parameters did not differ from the control group, which indicated that application of Antiadhesin® prevented formation of a connective tissue scar which could compress the dural sac and cause its deformation. In group A in the area of surgical intervention, granulomas with Pirogov-Langhans cells were detected, both in the soft tissues and in the lumen of the spinal canal. These findings in perioperative tissues might be related to biocompatibility and indicate their reaction to a gel as a foreign body. Conclusion: In clinical practice optimal materials for the prevention of epidural fibrosis are missing. There is an obvious need for further research in order to obtain implants capable of inhibiting and reducing the formation of epidural fibrosis. Keywords: Dura mater, epidural fibrosis, prevention, experiment, laminectomy, Antiadhesin®.
THE ROLE OF ENDOTHELIAL DYSFUNCTION IN THE PATHOGENESIS OF LIVER FAILURE IN OBSTRUCTIVE JAUNDICE OF BENIGN ORIGIN
Authors:   Department of General Surgery № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, GULOV M.K. , RUZIBOYZODA K.R. ,   Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, ABDULLOZODA S.M. ,   Department of Epidemiology, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: August 2022

Objective: To study the role of endothelial dysfunction in the pathogenesis of liver failure (LF) in obstructive jaundice of benign origin (OJBO). Methods: The study was based on the analysis of the results of a clinical examination of 68 patients with varying degrees of OJBO severity. For the determination of the severity of OJBO the classification proposed by Galperin EI (2012) was used. The class A severity was noted in 28 (43.7%) patients, class B – in 20 (36.5%) patients. The class C was determined in 20 (19.8%) patients which developed sepsis, encephalopathy, mono- or multiple organ failure. To assess endothelial dysfunction and its significance in the pathogenesis of OJBO and LF, the levels of markers of endothelial dysfunction in blood were assessed in patients with OJBO at various degrees of its severity. Results: The progression of OJBO, especially in patients with class B and C, contributed to a more pronounced changes of the level of markers of endothelial dysfunction and endotoxemia, leading to the development of LF. Thus, the increase in the level of mid-molecules (MM) in patients with OJBO complicated by LF reached 0.973±0.68 units, while with cholangitis added it comprised 0.1274±0.7 units; conjugated dienes (DC) levels were 1.58±0.17 mmol/ml of serum and 1.97±0.10 mmol/ml of serum; malondialdehyde (MDA) – 3.9±0.12 nmol/ml of serum and 4.8±0.16 nmol/ml of serum; the level of nitric oxide (NO) decreased up to 19.2±1.3 μmol/l and 16.4±1.4 μmol/l and the level of thrombomodulin – up to 78.6±5.4 pg/ml and 53.4±4.3 pg/ml, respectively. There was a significant increase in the indices of circulating desquamated endotheliocytes (CDE) up to 8.4±0.1 %/100 μl and 13.9±1.2 %/100 μl; and the level of endothelin-1 reached 1.2±0.07 fmol/ml and 1.4±0.05 fmol/ml, respectively, which was caused by the activation of free radicals. In addition, there was an increase in the diameter of the portal vein (1.02±0.03 cm and 1.921±0.02 cm), as well as linear (19.8±1.3 cm/ sec and 25.1±1.4 cm/sec) and volumetric (1321±124 ml/min and 1647±140 ml/min) blood flow velocities. Conclusion: With the progression of the OJBO (class B and C), significant and pronounced changes were found in the indicators of oxidative endotoxemia, hypoxia and cytokine profile, as well as marked circulatory disorders in the liver, directly correlating with the severity of endothelial dysfunction, which is the leading mechanism for the LF development. Keywords: Obstructive jaundice, cholestasis, cholemia, cholangitis, endothelial dysfunction, liver failure.
NUTRITION CONSIDERATIONS FOR CHILDREN AND ADOLESCENTS OF THE CULTURE AND ART EDUCATIONAL INSTITUTIONS
Authors:   Department of Hygienic Disciplines, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Republic of Kyrgyzstan, KERIMBAEVA I.B. , ESENAMANOVA M.K. ,   Department of Hygienic Disciplines, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Republic of Kyrgyzstan, KOCHKOROVA F.A. ,   Department of Hygienic Disciplines, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Republic of Kyrgyzstan, TSIVINSKAYA T.A. ,   Department of Hygienic Disciplines, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Republic of Kyrgyzstan
Published: August 2022

The review analyzed the results of research on the nutritional status of students of choreography and music schools. The following databases were used as sources of information: PubMed, RSCI, Google Scholar, CyberLeninka, Web of Science, Scopus, MEDLINE. During the literature search scarce research data were found regarding nutrition of students of choreography and music schools, while many more information was available regarding their physical development. According to available data, the physical development of students of ballet schools is characterized by unique features depending on gender, age, ethnicity and region of residence, in contrast to students of music and comprehensive schools. Meanwhile, nutrition of children and adolescents professionally trained in choreography and instrumental music was worked out without taking into account the age and gender of students, as well as training-related physical and neuro-emotional load. This fact indicates the need for additional research on rationalization of their nutrition. Keywords: Nutrition, nutritional status, children and adolescents, physical development, morbidity, music school, choreographic school.
Şərəfli ömürün səhifələri: Professor Həsən Abbas oğlu Sultanov
Authors:   Azərbaycan Tibb Universiteti, Bayramov Nuru , Rüstəm Ədalət ,   Azərbaycan Tibb Universiteti, Əliyev Eldar ,   Azərbaycan Tibb Universiteti
Published: August 2022

Kitab əməkdar elm xadimi, əməkdar həkim, Tibb elmləri doktoru, Professor Həsən Abbas oğlu Sultanovun əziz xatirəsinə həsr olunmuşdur. Kitab H. A. Sultanovun həyatı və elmi ya¬ra¬dıcılığını, cərrahlıq elminin, klinik cərrahlığın, xüsusi ilə prak¬tik cərrahi koloproktologiyanın inkişafına alimin böyük töh-fələrini özündə əks etdirmişdir. Alim haqqında, onun həkim¬lik fəaliyyəti və elmi tədqiqatlarının nəticələri barədə həm¬kar¬la¬rının, tələbələrinin səmimi fikirləri, təəssüratları və xoş xatirələri geniş işıq¬lan¬mışdır. Tibb tariximizin çanlı və şanlı əfsənələrindən biri haqqında yazılmış bu kitab onun yaddaşlardan heç zaman silinməyəcək xatirəsinə həmkarlarının və tələbələrinin kiçik hədiyyəsidir.
Qarın boşluğunun odlu silah yaralanmalarına yanaşma prinsipləri
Authors:   Azərbaycan Tibb Universiteti, Bayramov Nuru , Əzimov Elman ,   Azərbaycan Tibb Universiteti
Published: August 2022

The book contains general rules for the surgical treatment of gunshot wounds of the abdominal cavity in field hospitals. The rules were developed on the basis of the experience of the Karabakh war and information from the literature.
Canlı qaraciyər donorlarının müayinəsi, müalicəsi və əməliyyatdan sonrakı izlənməsi qaydaları
Authors:   Azərbaycan Tibb Universiteti, Bayramov Nuru , Məmmədov Ruslan ,   Azərbaycan Tibb Universiteti, Novruzov Namiq ,   Azərbaycan Tibb Universiteti, İsazadə Elvin ,   Azərbaycan Tibb Universiteti, Bayramova Təranə ,   Azərbaycan Tibb Universiteti
Published: August 2022

This book provides recommendations for preoperative, intraoperative, and postoperative evaluation and management of living liver donors.
Pengaruh Perendaman Gigi Dengan Teh Hijau (Camellia Sinensis) Terhadap Kekerasan Gigi Setelah Direndam Dengan Minuman Bersoda
Authors: Ramadhani Dina Kharina , Hidayati Hidayati , Kustantiningtyastuti Didin
Published: August 2022

Tooth erosion is the loss of important dental structure minerals due to continuous acid exposure, due to the low pH and high calories found in soft drinks. Loss of mineral elements in tooth enamel reversible or can still return to normal through the process of remineralization. Adding fluorine, calcium, phosphorus from green tea can increase resistance from remineralization of email toward acids, in other words it can inhibit acid formation by binding to enamel minerals and forming fluorapatite compounds. Objective: To determine the increase of tooth hardness enamel after being soaked with green tea (Camellia Sinensis) toward the teeth soaked with soft drinks using the Vicker Hardness Tester. Research method: This study is a true experimental study with a pre-test and post-test with control group design. The samples of this study were upper premolar teeth adjusted for inclusion criteria. 10 samples were immersed in carbonated drinks for 25 hours, then the samples were divided into two groups, 5 samples were immersed in green tea and the other 5 samples were soaked in artificial saliva for 25 hours. Measurement of tooth hardness using the Vicker Hardness Tester. Results: The data was analysed using paired t-test. Tooth hardness decreased after being soaked with the carbonated drinks (mean = 42.80 with DS = 6.98), then increased after being soaked with green tea (mean = 95.39 with DS = 10.86), p <0.001 also increased in the saliva group (mean = 76.29 with DS = 11.33). Conclusion: There is the effect of immersion with green tea (Camellia sinensis) on the hardness of the enamel surface of the teeth after soaking with soft drinks.
Azithromycin and the Outcome of Treated COVID-19 Patients: A Hospital-Based Study
Authors: Usman Elly
Published: August 2022

COVID-19 is an infectious disease that has been declared a pandemic. Currently, there is no validated pharmacological treatment for use in COVID-19 disease and is still in the clinical trial stage. The aim of this study to determine the association of azithromycin and the outcome of treated COVID-19 patients. This study used a retrospective cohort.  The number of samples in this study were 40 subjects in each group of azithromycin and non-azithromycin. The research sample was all COVID-19 patients who were treated at Dr. M Djamil Hospital Padang with moderate and severe grades receiving treatment with azithromycin and non-azithromycin. The inclusion criteria in this study were moderate and severe COVID-19 patients and data related to research variables were complete and well-documented. Sampling technique with convenience sampling. Data analysis was performed using the Chi-square test. P < 0.05 was significant, and the data were analyzed using the SPSS version 21.0 program. The mortality of COVID-19 patients in patients receiving azithromycin therapy (80.0%) compared to non-azithromycin (85.0%). The results of the statistical test showed that there was no relationship of azithromycin administration with the outcome of COVID-19 patients (p>0.05), with OR (0.71, 95% CI 0.22-2.26). In this study, it is hoped that the decision on the use of azithromycin should consider the potential benefits and risks, evaluated that the possibility of the drug being effective is greater than the risk to the patient.
Mediation model of media determinants of water rates
Authors:   Department of Psychology, Universidad Nacional Autónoma de México, Mexico, Aguayo José Marcos Bustos , Lirios Cruz García ,   Department of Social Work, Universidad Autónoma del Estado de México, Mexico, Córdoba Víctor Hugo Meriño , Guillén Javier Carreón , Miranda Miguel Bautista , Nájera Margarita Juárez , Vázquez Francisco Rubén Sandoval
Published: August 2022

The press, by spreading the availability of resources, shortages linked with preservation. In this sense, the work explores nine briefings from 2019 to 2022 published in national newspapers regarding the lack of supply, quality, benefit, punishment and discomfort as a consequence of the water situation in a demarcation east of Mexico City. This finding was considered as evidence of a moderate degree of media coverage the press regarding the problems arising from water shortages. From the results discussed its implications with other studies conducted in the demarcation.
KEMAMPUAN PENALARAN PROPORSIONAL MATEMATIS SISWA DENGAN GAYA BELAJAR FIELD INDEPENDENT
Authors: Taufik Azin
Published: August 2022

This study aims to describe the results of the analysis of students' mathematical proportional abilities in terms of independent field learning styles. This research was conducted at MTs Nurul Huda Beringin in September Odd Semester, Academic Year 2020/2021 with a total of 9 students of class VII A. The research subjects were selected by purposive sampling, consisting of 2 students with independent field cognitive style. The research method used is descriptive qualitative with a case research design. The data technique used the Group Embedded Figures Test, mathematical proportional reasoning ability tests, in-depth interviews and observations. Data analysis techniques were performed by data reduction, data presentation, and data retrieval. The technique of checking the validity of the data used the technique triangulation method. The results showed that: (1) There were 2 students who had a cognitive style in the field. (2) Students with field independent cognitive style, namely LH and DK subjects are at level 3 formal proportional reasoning, the second subject has been able to meet the indicators of finding values or quantities to compare, indicators find relationships between values or quantities and indicators use appropriate procedures in calculating comparisons.
Home Equity Loans in Texas: Maintaining the Texas Tradition of Homestead Protection
Authors: Patterson Forrester Julia
Published: August 2022

This Article examines home equity financing in Texas, focusing on how continued protection of the homestead shelters Texas homeowners from problems experienced by some homeowners in other states. In Part I of the Article, I briefly explore the history of homestead protection and home equity loans in Texas, a subject on which Joe McKnight literally wrote the book. In Part II, I discuss the growth of home equity loans in other states, the reasons for their popularity, and the problems that have arisen for homeowners who have been victimized by predatory lenders. Part III examines the constitutional amendment that ultimately permitted home equity lending in Texas, focusing on the consumer protection requirements of the provision and how they are aimed at preventing predatory lending practices. In Part IV, I discuss criticism aimed at the amendment and problems that have arisen in interpreting and applying it. Part V discusses the limited legislative response to these issues and the court cases interpreting the amendment. In the Conclusion, I address the criticisms of the constitutional provision and defend its consumer protection measures.
Rethinking Powers of Attorney in Real Estate Transactions
Authors: Patterson Forrester Julia
Published: August 2022

The Uniform Power of Attorney Act, adopted in 2006, was designed to address the divergence of various states from the original uniform act and to address problems identified by attorneys practicing in the area. One such problem was the refusal of parties to accept powers of attorney—although a client might execute a durable power of attorney as part of an estate plan to avoid a guardianship, parties would refuse to deal with the agent, thus necessitating a guardianship proceeding. The Uniform Act has now been enacted in some form in more than half of the states, including Texas. The author examines the Uniform Act and the Texas Act in the context of powers of attorney in real estate transactions. She discusses common law rules relating to defective deeds, defective powers of attorney, and deeds executed by an agent under a defective power of attorney, as well as the effect that the Uniform and Texas Acts may have on the common law. The article concludes by recommending additional legislation to clarify the application of the Acts and to make them more compatible with solving the problems that may arise in the context of real estate transactions.
Tratamento cirúrgico do câncer de pele não-melanoma: revisão narrativa
Authors: Santos Renata Gonçalves , Boechat Alexandre Strapasson , Leite Thaís Cançado , Freitas Marianne Borges , Carvalho Beatriz Maciel de , Lopes Amanda Brandão , Oliveira Éricles Willy Machado de , Lopes Mateus Huang , Mendes Jorge Henrique Lopes , Lobato Michele Silva
Published: August 2022

Objetivo: Fornecer através de uma revisão narrativa uma ampla abordagem sobre o tratamento cirúrgico do Câncer de Pele Não-Melanoma (CPNM). Revisão bibliográfica: O CPNM, que corresponde ao Carcinoma Basocelular (CBC) e ao Carcinoma Espinocelular (CEC), é atualmente o câncer mais comum no mundo em todas as faixas etárias e em ambos os sexos. Esse tipo de neoplasia apresenta menor índice de mortalidade se tratada de forma correta. O principal fator de risco conhecido associado ao desenvolvimento da doença é a exposição excessiva e crônica ao sol. Uma vez diagnosticado pelo dermatologista o CPNM possui uma série de tratamentos disponíveis que varia de acordo com as características de cada lesão. A cirurgia tanto para o CBC quanto para o CEC, é considerada o tratamento de escolha pelos profissionais da área, apresentando as maiores taxas de cura e menores taxas de recidivas. Considerações finais: A detecção precoce dos casos de CPNM e instituição de tratamento adequado em tempo hábil é fundamental para evitar desfechos desfavoráveis. A abordagem cirúrgica atualmente é considerada a melhor estratégia terapêutica para esse tipo de neoplasia.
Literasi sikap kemandirian dalam berwirausaha melalui metode pembelajaran daring bagi mahasiswa peserta PMM prodi Pendidikan Sejarah UNIPMA
Authors: Soebijantoro S , Septianingrum Bela
Published: August 2022

Penelitian ini dilakukan dengan tujuan untuk mengetahui bagaimana implementasi literasiÂ  kemandirian dapat meningkatkan sikap kemandirian mahasiswa peserta Pertukaran Mahasiswa Merdeka (PMM) melalui metode daring pada pembelajaranÂ  historiopreneurship di eraÂ  pandemi Covid 19. Metode penelitian yang dipergunakan adalah metode deskriptif kualitatif yaitu berupa studi kasus. Sumber data diperoleh melalui wawancara, angket , studi arsip dan dokumen serta observasi langsung. Adapun pengumpulan data dilakukan melalui observasi, wawancara, dan studi dokumentasi. Observasi dilakukan dengan pengamatan langsung secara non partisipasi dalam berbagai kegiatan pembelajaran di kampus. Wawancara dilakukan baik secara terstruktur dengan daftar pertanyaan yang telah disistematisasikan berdasarkan gambaran awal yang didapat ataupun secara. Sedangkan data peningkatan sikap kemandirian dilakukan dengan menggunakan angket yang dianalisa melalui skala likert. Secara keseluruhan analisis data penelitian ini berpedoman pada langkah-langkah analisis data penelitian kualitatif dari Moleong (2011), yaitu: reduksi data, penyajian data, danÂ  penarikan simpulan. Dari analisis data diperoleh hasil 1)Â  Diperlukan literasi kesejarahan sebagai sebuah ilmu pengetahuan tentang masa lampau yang bermanfaat bagi manusia serta melakukan komersialisasi dengan jiwa dan semangat yang mampu menghadirkan produk-produk hasil kajian kesejarahan yang bisa diterima oleh masyarakat.2) Terdapat data peningkatan sikap kemandirian mahasiswa yaitu dengan 75,2 % responden mahasiswa PMM menunjukkan sikap sangat setuju bahwaÂ  sikap kemandirian merupakan kunci keberanian seseorang untuk menekuni bidang kewirausahaan, 3) 81,3 % mahasiswa menyatakan bahwa di era transformasi digital, pariwisata sejarah merupakan bidang garapan lulusan prodi Pendidikan sejarah serta merupakan peluang bisnis yang sangat menjanjikan.
Situs mangiran Desa Sidorejo Kabupaten Madiun sebagai sumber belajar sejarah lokal
Authors: Lestari Anida Putri , Soebijantoro S
Published: August 2022

Penelitian bertujuan untuk mengetahui potensi yang terdapat pada Situs Mangiran yang dapat dipergunakan sebagai sumber belajar sejarah lokal. Penelitian dilakukan di situs mangiran Desa Sidorejo Kecamatan Saradan Kabupaten Madiun. Metode yang dipergunakan adalah deskriptif kualitatif melalui observasi, wawancara dan studi dokumentasi. Observasi dilakukan secara non partisipasi dalam berbagai kegiatan masyarakat. Wawancara dilakukan secara terstruktur dengan daftar pertanyaan yang telah disistematisasikan berdasarkan gambaran awal yang di peroleh. Analisis data berpedoman pada reduksi data, penyajian data danÂ  penarikan simpulan. Dari hasil analisa data ditemukan bahwa potensi situs mangiran sebagai sumber belajar sejarah lokal adalah Pertama, memberikan pemahaman kepada siswa bahwa situs tersebut semakin memperkuat fakta bersama situs lain yang diketemukan di wilayah Kabupaten Madiun tentang dinamika sosial ekonomi dan budaya masyarakatÂ  yang mencerminkan corak budaya Majapahit, Kedua menambah dan memperluas pengetahuan siswa bahwa sejarah Madiun diwarnai sejumlah kekuatan politik yang silih berganti untuk menguasai wilayah Madiun sejak zaman klasik, mulai dari kekuatan politik yang bersifat lokal hingga kekuatan politik yang merupakan bagian dari kerajaan besar, seperti Singosari, Majapahit, Demak hingga Mataram Islam.
Implementasi nilai-nilai kejuangan raden ajeng kartini di SMPN 3 Madiun
Authors: Sari Andani Arum , Wibowo Anjar Mukti
Published: August 2022

Di dalam sejarah Indonesia penelitian mengenai perempuan termasuk penelitian yang masih kurang mendapat perhatian dibanding penelitian di bidang ilmu sosial yang lain. Ilmu sosiologi dalam hal ini merupakan contoh untuk penelitian mengenai perempuan. Saat ini penelitian mengenai peran perempuan dalam sejarah masih sedikit sehingga menarik untuk dikaji. Raden Ajeng Kartini adalah salah satu tokoh perempuan Indonesia yang telah mendapatkan perhatian. Sejak lama telah dikumandangkan perjuangan dan pemikirannya mengenai emansipasi wanita. Nilai-nilai bisa digali atas perjuangan dan pemikirannya lalu diimplementasikan oleh generasi sekarang. Penelitian ini mengungkap bentuk penerapan nilai-nilai kejuangannya pada SMPN 3 Madiun. Penelitian ini menggunakan pendekatan deskripsi kualitatif studi kasus dengan teknik purposive sampling yang menggunakan beberapa informan yang ditunjuk sebagai subjek penelitian. Kemudian analisis data menggunakan observasi, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa di SMPN 3 Madiun sebenarnya telah menerapkan nilai-nilai kejuangan Kartini bagi seluruh warga sekolah sejak dahulu dan tidak terlepas melalui pembiasaan dan keteladanan.
Umating agama adam dalam perspektif sejarah samin di Bojonegoro
Authors: Triana Habsari Novi , Nurdianti Sieva Inda
Published: August 2022

Penelitian ini bertujuan untuk mengetahui persepsi masyarakat Samin di Bojonegoro terhadap kepercayaan Umating Agama Adam. Penelitian ini dilakukan selama 4 bulan yaitu antara bulan Februari sampai Juni. Bentuk penelitian ini yaitu penelitian kualitatif. Jenis penelitian yang digunakan yaitu jenis penelitian deskriptif. Teknik pengambilan data yaitu dengan menggunakan metode wawancara, observasi, dan dokumentasi. Sumber data yang dipakai yakni sumber data primer dan sumber data sekunder. Teknik keabsahan data yang digunakan untuk menguji kebenaran data yaitu trianggulasi sumber. Analisis data yang digunakan adalah analisis data model interaktif Miles dan Huberman. Hasil penelitian didapat bahwa masyarakat Samin memiliki aliran kepercayaan yang disebut agama Adam. Hyang Wenang Pramesti Agung adalah sebutan masyarakat Samin kepada Allah SWT dan menganggap dirinya sebagai Umating Agama Adam Kawitan. Meskipun tidak mempunyai agama yang diakui oleh Negara, namun perilaku masyarakat Samin sangat terpuji, saling menolong, jujur, dan mengahargai sesama terbukti saat ini sudah banyak didirikan masjid dan gereja. Saat ini terdapat 5 masjid dan 1 gereja jawi wetan (GKJW) di Desa Jepang. Kecamatan Margomulyo Kabupaten Bojonegoro. Para penganut agama Adam memiliki toleransi yang tinggi dan mampu hidup berdampingan dengan masyarakat di luar Samin.
Resiliensi Millenial Terhadap Ekonomi Kreatif Pada Masa Pademi Covid-19 di Pasuruan
Authors: Nurhayati Dies , Mutmainah M , Hasanah Nikmatul , Luthfiani Puput
Published: August 2022

Covid-19 juga membawa perubahan besar yang tidak direncanakan pada hampir seluruh aspek kehidupan masyarakat dunia. Perubahan ini menuntut kita mampu beradaptasi dan bangkit dari kesulitan yang timbul saat pandemi covid-19 ini. Kemampuan beradaptasi dan bangkit ini disebut resiliensi.Millenial kami pilih sebagai target penelitian ini dikarnakan millenial adalah simbol perubahan generasi yang membawa perubahan gaya hidup menjadi serba digital.Penelitian ini menitik beratkan resiliensi ekonomi kreatif millenial karna pada masa ini millenial adalah generasi yang mendominasi pasar kerja. Penelitian ini menggunakan metode penilitian lapangan, studi kepustakan, serta pengambilan sample menggunakan teknik purposive sampling di Kota Pasuruan dan Kabupaten Pasuruan
SALUD PERIODONTAL EN LOS PACIENTES QUE SUFRIERON COVID 19
Authors: Palma Chuque Grisselda del Rosario , Odiaga López Diana Carolina , Fernández Arrascue María Julia , Ojeda Gomez Roberto
Published: August 2022

Al término del año 2019 en la ciudad de Wuhan en China, surgió el brote de un virus llamado SARS-CoV2 (COVID-19). Este virus es tan mortal que en pocos meses afecto alrededor de 180 países. Las personas infectadas por ese virus, presentan un Síndrome de dificultad respiratoria aguda o eventos trombóticos pulmonares y lo penoso es que aquellas que sobrevivieron ante esta situación, quedan con un alto porcentaje de secuelas pulmonares. Además, existen pacientes que están en un estado crítico por COVID-19, los cuales son más propensos a desarrollar lesiones periodontales, ulcerativas y también hiperpigmentación del paladar duro, tanto por los fármacos utilizados para su recuperación como también por la entubación del paciente y la disminución del microbiota, apareciendo nuevos patógenos que agraven las lesiones bucales.

Para la redacción de este artículo de revisión se utilizó el buscador académico Google Scholar y se seleccionaron 10 artículos como criterios de inclusión: estaban en español, publicados hace menos de 10 años y mostraban datos sobre enfermedades Periodontales. Los resultados indican que los medicamentos como los corticoides dañan la cavidad bucal.

Por eso es importante mencionar que aquellos pacientes que sufrieron de COVID 19, tuvieron una deficiencia en el aseo de sus dientes, dado que, por estar con oxígeno o con respirador artificial la limpieza oral no se realizaba cada 12 horas o al encontrarse inmovilizados esta tampoco se realizaba. Por otro lado, se debe recalcar que el uso excesivo de terapia farmacológica puede agravar las enfermedades bucales a través de mecanismos inmunes.
Insight into the mechanism of DNA synthesis by human terminal deoxynucleotidyltransferase
Authors: Kuznetsova Aleksandra A , Tyugashev Timofey E , Alekseeva Irina V , Timofeyeva Nadezhda A , Fedorova Olga S , Kuznetsov Nikita A
Published: August 2022

Terminal deoxynucleotidyltransferase (TdT) is a member of the DNA polymerase X family that is responsible for random addition of nucleotides to single-stranded DNA. We present investigation into the role of metal ions and specific interactions of dNTP with active-site amino acid residues in the mechanisms underlying the recognition of nucleoside triphosphates by human TdT under pre–steady-state conditions. In the elongation mode, the ratios of translocation and dissociation rate constants, as well as the catalytic rate constant were dependent on the nature of the nucleobase. Preferences of TdT in dNTP incorporation were researched by molecular dynamics simulations of complexes of TdT with a primer and dNTP or with the elongated primer. Purine nucleotides lost the “summarised” H-bonding network after the attachment of the nucleotide to the primer, whereas pyrimidine nucleotides increased the number and relative lifetime of H-bonds in the post-catalytic complex. The effect of divalent metal ions on the primer elongation revealed that Me2+cofactor can significantly change parameters of the primer elongation by strongly affecting the rate of nucleotide attachment and the polymerisation mode.
Fourth World Congress of Sports Physical Therapy Scientific Abstracts
Authors:   International Federation of Sports Physical Therapy,   International Journal of Sports Physical Therapy
Published: August 2022

The International Journal of Sports Physical Therapy is pleased to publish abstracts from the 4th World Congress of Sports Physical Therapy, which will take place in Nyborg, Denmark, August 26-27, 2022. The theme of the Congress is “Translating Science into Actioon.” The variety of presentations during this congress are examples of the contemporary sports physical therapy research activities taking place around the world.

The abstracts presented in the following pages were selected by the Scientific Committee, which included members from and from the International Federation of Sports Physical Therapy. It should be noted that abstracts have not been reviewed by the Editorial Board, Associate Editors or Editor-in- Chief of the International Journal of Sports Physical Therapy.

After careful review by an international team of reviewers, research abstracts will be presented by authors at the World Congress.

Each abstract presents only a brief summary of a research project / presentation and does not permit full assessment of the scientific rigor with which the work was conducted. While the abstracts offer only preliminary results that may require further refinement and future validation, they do serve an important role of sharing new research ideas from around the world. This sharing of ideas helps to encourage worldwide dialogue among researchers, clinicians, and educators that will ultimately contribute to the sports physical therapy body of knowledge.

Notice: The abstracts below are presented as prepared by the authors. The accuracy and content of each abstract remain the responsibility of the authors.
A Comparison of Pitching Biomechanics and Sport Specialization in High School Pitchers
Authors: Hamer Tyler J. , Rosen Adam B. , Wilkins Samuel J. , Nicholson Kristen F. , Bullock Garrett S. , Knarr Brian A.
Published: August 2022

Background

The prevalence of sport specialization in high school athletes continues to rise, particularly among baseball players. Previous research has focused on the incidence of injury among specialized and non-specialized athletes but has yet to examine the level of sport specialization and pitching biomechanics.

Hypotheses/Purpose

The purpose of this study was to investigate differences in pitching volume and biomechanics between low-, moderate-, and high-level specialized baseball pitchers. It was hypothesized that high-level specialized pitchers would have the most pitching volume within the current and previous years while low-level specialized pitchers would exhibit the least amount. The second hypothesis states that kinematics and kinetics commonly associated with performance and injury risk would differ between low-, moderate-, and high-level specialized pitchers.

Study Design

Case-Control Study

Methods

Thirty-six high school baseball pitchers completed a custom sport specialization questionnaire before participating in a three-dimensional pitching motion analysis. Sport specialization was based off current guidelines and categorized as low-, moderate-, and high-level specialized based upon self-reported outcomes. Pitchers then threw ≈10 fastballs from a mound engineered to professional specifications. Data averaged across fastballs was used for biomechanics variables. Key pitching biomechanical and pitching volume variables were compared between low-, moderate-, and high-level specialized pitchers.

Results

High-level specialized pitchers were older (p = 0.003), had larger body mass (p = 0.05) and BMI (p = 0.045), and threw faster (p = 0.01) compared to low-level specialized pitchers. Pitching volume and pitching biomechanics were similar across groups.

Conclusions

Pitching biomechanics were similar across groups, although high-level specialized pitchers threw with significantly higher throwing velocity compared to low-level pitchers. The low amount of pitching volume throughout the season may be responsible for the lack of additional observed differences. Further research should examine the relationship between pitching biomechanics, upper extremity strength and flexibility, and sport specialization.

Level of Evidence

Level III
Timbral Processes in Three Selected Works by Olga Neuwirth, Kaija Saariaho and Clara Iannotta, and Their Influence on a Portfolio of Creative Works
Authors:   , Ballard Sarah
Published: August 2022

The instrumental music of composers Olga Neuwirth, Kaija Saariaho and Clara Iannotta inhabits an inventive sphere of approaches to timbre, inviting a variety of possibilities of considering how sound can be organised to create compelling narratives with timbre as a key parameter. This research aims to define the individual sound units within three of these composers’ ensemble works and to determine how these sound units are assembled, how they interact with one another, and how their functions operate throughout the course of the work. These works are Vampyrotheone (1995) for three soloists and three ensemble-formations, Oi Kuu (1990) for bass clarinet and cello, and Àphones (2011) for 17 instruments. The intended outcome of this research is to enable an understanding of the form-creating forces throughout these works, which are conceived through a timbre-based approach, and how this might allow for insight into the compositional process of the composers. Aspects of these various approaches will be discussed in relation to a portfolio of my own works, encompassing a range of forces including works for accordion and clarinet, orchestra and chamber ensemble.
Prediction of Knee Injury in Professional Soccer Players Using Core Endurance and Strength: A Cross-sectional Study
Authors:   Cairo University, Faculty of Physical Therapy, Department of Biomechanics, Giza, Egypt, El Megeid Abdallah Amira Abdallah Abd , Afifi Hegazy Mostafa ,   Southwest Minnesota State University, Department of Science, Marshall, MN, USA
Published: August 2022

Although relationships between lower limb injury and core strength and endurance have been reported, limited research on the risk of knee injury specifically among soccer players exists. This study aimed to compare preseason trunk muscle endurance as well as trunk and hip muscle strength between soccer players who experienced knee in- jury during their season and those who did not. Dependent variables were also used to predict the risk for injury. This prospective cross-sectional study involved thirty-nine male soccer players (age 19.64±2.84 years, weight 73.94±15.66 kg and height 175.67±9.92 cm). By the end of the season, twelve (30.77%) reported knee injuries. Accordingly, two groups were identified and compared: injured and non-injured. Prone-bridge, side-bridge, trunk flexion and hor- izontal back extension hold times were used as trunk endurance measures, while peak isokinetic trunk flexor and extensor torques, as well as hip abductor and external rotator torques, were recorded as strength measures. MANOVA showed that only prone-bridge hold time was significantly higher in the non-injured players (p<0.05). Logistic re- gression showed that prone-bridge hold time and peak isokinetic hip abductor torque were significant predictors of injury (OR=0.97&0.03, respectively). Thus, soccer players with knee injuries have lesser core endurance. Reduced prone-bridge hold time and abductor torque, specifically, are associated with an increased risk of injury.
Effects of Two Types of Warm-Up Exercises on Vital Capacity and Forced Vital Capacity Values
Authors:   University of Mosul, College of Physical Education & Sport Science, Mosul, Iraq, Sami Hasan Mazin , Abdulgani Taha Ahmed ,   University of Mosul, College of Physical Education & Sport Science, Mosul, Iraq, Baiz Tawfeeq Rebaz ,   Koya University, School of Physical Education, Erbil, Iraq
Published: August 2022

Valuable information can be obtained about the respiratory system when performing lung function tests. These tests show differences in pulmonary functional quantities, which can be attributed to many factors. Some fac- tors that may significantly affect the optimal pre-test values for pulmonary function may appear, including the subject’s physical condition before testing. This study aims to analyse the physiological effects of various types of warm-ups exercises and their effect on pre-test results of respiratory variables of Vital Capacity (VC) and Forced Vital Capacity (FVC). Sixteen healthy males participants ages (19–21) years (20.08±1.55 years) were in- tentionally selected. The homogeneity of age, height, mass, Vital Capacity (VC), and Forced Vital Capacity (FVC) was verified. The results of VC and FVC tests were taken before and after field and laboratory warm-ups; the laboratory warm-up was performed on a treadmill. The study revealed significant differences in the VC results between non-warm-ups compared with the VC predicted values. No significant differences between field and laboratory warm-ups compared with VC predicted value were found. Significant differences in the VC results after the field and laboratory warm-ups compared to non-warm-up results were recorded. The study showed significant differences in the FVC results between non-warm-ups compared with FVC predicted value. No sig- nificant differences between field and laboratory warm-ups compared with FVC predicted value were found. Significant differences in the FVC results after the field and laboratory warm-ups compared to non-warm-up results. We observed that warm-up exercises had a positive effect on variable-related results for VC and FVC, especially when the warm-up was in the lab.
Association of Laboratory and Field Balance Test
Authors:   University of Split, Faculty of Kinesiology, Split, Croatia, Pavlinovic Vladimir , Foretic Foretic Nikola ,   University of Split, Faculty of Kinesiology, Split, Croatia, Versic Sime ,   University of Split, Faculty of Kinesiology, Split, Croatia
Published: August 2022

Balance can be defined as keeping the center of gravity of the body within the surface of the support and has crucial role in sport. However, there are insufficient knowledge regarding balance field testing. The main aim of this study was to determine association between Biodex laboratory balance test and Y balance field test. The participants in this study were 12 students (6 males, 6 females) of Faculty of Kinesiology in Split, Croatia. The set of variables includ- ed anthropometric measures (body height, body weight, body mass index), two laboratory balance tests conduct- ed on Biodex (Postural stability test, Limits of stability test) and field balance test (Y balance test). The correlations between observed variables were calculated by Pearson's product moment correlation. No significant correlations were found between Y balance test and both Postural stability test (r=-0.06 and 0.02 respectively for left and right leg) and Limits of stability test (r=-0.06 and 0.02). The results of this study indicate that Y balance test is not a precise measure of balance ability in well-trained individuals. Authors hypothesize that Y balance test performance is great- ly influenced by lower extremity strength and mobility. There is an obvious need for the construction and validation of new field tests to assess the level of balance in amateur and professional athletes.