bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the role of service delivery and its impact on the functionalities of women in Njane and Ntshaseni communities of the Ubuhlebezwe Local Municipality (ULM) in KwaZulu-Natal.
Authors:   , Ngubo Wandile Noxolo
Published: January 2024

Service delivery in most South African rural areas is neither efficiently nor equitably distributed. This makes residents receive poor quality services which are often unavailable. Feminist geography is concerned, among other things, with how gender and geography determine the welfare of communities. This study looked at service delivery from a geographical dimension of rurality and remoteness and connected this to gender-based service perceptions. The first paper looked at service delivery ratings of men and women in two rural communities in the same municipality-the Ubuhlebezwe Local Municipality (ULM) in KwaZulu-Natal. These communities are remote in terms of distance from major urban centres. The study utilised a quantitative research approach, with a sample of 200 residents from Njane and Ntshaseni. The study was designed as a comparative descriptive study. The first objective of the study was to assess men and women's ratings on the provision of such services as road, healthcare, education, water and sanitation, and electricity. The second objective was to compare the relationship between water and energy services delivery and women's domestic workload (WDW) in the two communities. The second paper used a sample of 127 and used a descriptive approach to analyse data on water and sanitation and electricity and used secondary data that was collected in previous studies on the two communities and analysed this on SPSS and Microsoft Excel. The research findings have revealed that women rate service delivery quality and availability very lowly compared to men. Women’s low ratings revealed that service delivery quality and availability affected them differently from men, with regards to healthcare, water and sanitation, and electricity services. The research findings have also revealed that women are heavily burdened by lack of water and electricity in Njane and Ntshaseni communities, leading to increased domestic workloads. The study recommends a nexus of geography and gender in dealing with service delivery challenges. Local governments need to provide gender-sensitive service delivery in remote communities. This approach would reduce geography and gender service delivery disparities, and relieve poor rural women from back-breaking domestic labour.
PENGARUH MODEL PEMBELAJARAN CLIS (CHILDREN LEARNING IN SCIENCE) TERHADAP HASIL BELAJAR PESERTA DIDIK PADA MATERI USAHA DAN ENERGI KELAS X DI SMA NEGERI 1 KUTA BLANG
Authors: Asmaya Asmaya , Faradhillah Faradhillah , Syafrizal Syafrizal , Novita Nanda , Zahara Syarifah Rita
Published: January 2024

Abstrak: Penelitian ini bertujuan adalah untuk mengetahui pengaruh model pembelajaran CLIS (Children Learning In Science) terhadap hasil belajar peserta didik pada materi usaha dan energi kelas X di SMA Negeri 1 Kuta Blang. Penelitian dilakukan menggunakan pendekatan kuantitatif dan menggunakan jenis quasi eksperimen design. Bentuk desain yang digunakan pada penelitian ini adalah Nonequivalent Control Group Design. Pengambilan data dilakukan di kelas X IPA 1 sebagai kelas eksperimen dan kelas X IPA 2 sebagai kelas kontrol. Teknik pengumpulan data yang dilakukan pada penelitian ini terdiri dari lembar observasi awal, soal tes, dan lembar Angket. Data penelitian ini diolah menggunakan perangkat lunak SPSS versi 16. Hasil penelitian menunjukkan bahwa nilai rata-rata post-test yang diperoleh kelas eksperimen 72,5 dan kelas kontrol 61,5. Pada uji hipotesis menggunakan uji independent sample t-test dengan taraf signifikan 0,05. Berdasarkan data uji independent sample t test diperoleh nilai signifikan (2-tailed) sebesar 0,016 < 0,05 maka   ditolak dan   diterima, hal ini dikarenakan nilai signifikan lebih besar 0,05. Dengan demikian dapat dikatakan bahwa terdapat pengaruh model pembelajaran CLIS terhadap hasil belajar peserta didik pada materi usaha dan energi kelas X di SMA Negeri 1 Kuta Blang.
Pengaruh Model Pembelajaran Kooperatif Tipe Student Team Achievement Division (STAD) Terhadap Hasil Belajar Fisika Siswa Di Sekolah Menengah Pertama Negeri 1 Kediri
Authors: Astuti Handayani Shintia , Meiliyadi Lalu Ahmad Didik , Ernita Nevi
Published: January 2024

Penelitian ini dilatar belakangi oleh rendahnya hasil belajar siswa pada mata pelajaran IPA di kelas VII, sehingga penelitian ini bertujuan untuk melihat pengaruh model pembelajaran kooperatif tipe STAD (Student Team Achievement Devision) Terhadap Hasil Belajar Siswa Kelas VII SmpN 1 kediri . Penelitian ini dirancang untuk menggunakan pendekatan kuantitatif. Penelitian ini adalah jenis penelitian yang menggunakan Quasi eksperimen. Sampel yang digunakan pada penelitian ini ada 2 kelas yang terdiri dari 60 siswa, dimana siswa kelas VIIA yang berjumlah 30 siswa menjadi kelas eksperimen yang diberi perlakuan model pembelajaran kooperatif tipe Student Team Achievement Devision dan kelas VIIB yang berjumlah 30 siswa menjadi kelas kontrol tanpa diberi perlakuan model pembelajaran konvensional . Instrumen yang digunakan pada penelitian ini adalah instrument observasi, dokumentasi dan tes. Dari hasil penelitian menunjukkan bahwa terdapat adanya perbedaan pada hasil belajar terhadap keduan kelas dengan perlakuan yang berbeda. Pada hasil belajar memiliki perbedaan hasil antara kelas eksperimen yang diberi perlakuan model pembelajaran kooperatif tipe Student Team Achievement Devision dengan nilai rata-rata pretest yaitu 39,40 dan nilai rata-rata posttest yaitu 81,33 dengan jumlah peningkatan yaitu 41,93. Sedangkan pada kelas kontrol yang diberi perlakuan model konvensional yaitu pada kelas pretest dengan nilai rata-rata 38,37 dan nilai rata-rata posttest yaitu 67,63 dengan jumlah peningkatan 29,26. Sehingga model pembelajaran kooperatif tipe Student Team Achievement Devision berpengaruh terhadap hasil belajar siswa.
PENERAPAN LKS BERBASIS CONTEXTUAL TEACHING AND LEARNING TERHADAP HASIL BELAJAR SISWA PADA MATERI GELOMBANG MEKANIK DI SMAN 4 PALANGKA RAYA
Authors: Wulandari Kartina Mahadewi
Published: January 2024

Penelitian ini bertujuan untuk melihat hasil belajar siswa setelah menggunakan LKS berbasis contextual teaching and learning pada materi gelombang mekanik. Penelitian ini dilakukan di SMAN 4 Palangka Raya. Jenis penelitian ini adalah penelitian kuantitatif dengan metode penelitian yang digunakan yaitu pre-experimental. Desain penelitian yang dipakai adalah one group pretest posttest design. Siswa kelas XI-MIPA 1 SMAN 4 Palangka Raya yang berjumlah 25 siswa merupakan sampel pada penelitian ini. Instrumen penilaian yang digunakan berupa tes soal uraian (essay) sebanyak 11 butir soal. Teknik analisis data menggunakan nilai gain dan n-gain, diperoleh nilai rata-rata gain sebesar 28,28. Sedangkan nilai rata-rata dari n-gain nya adalah 0,56 yang masuk dalam kategori sedang. Hal ini menunjukkan bahwa hasil belajar siswa meningkat setelah menggunakan LKS berbasis contextual teaching and learning pada materi gelombang mekanik. LKS berbasis contextual teaching and learning dapat mempermudah siswa dalam menghubungkan pengetahuan gelombang mekanik yang dimilikinya dengan kehidupan sehari-harinya.
Investigasi Pendekatan Saintifik: Mata Pelajaran Fisika di SMAN 15 Muaro Jambi untuk Meningkatkan Hasil belajar Siswa Kelas XII
Authors: Lusi Lusi Lusi
Published: January 2024

Penelitian ini bertujuan untuk mengidentifikasi Pendekatan saintifik yang digunakan guru dalam pembelajaran fisika. Metode yang digunakan adalah metode kualitatif dengan mewawancarai dan mengobservasi guru fisika yang ada di SMAN 15 Muaro Jambi. Subjek penelitian ini adalah guru fisika SMAN 15 Muaro Jambi. Hasil dari penelitian ini adalah bahwa guru fisika di sekolah tersebut sudah menggunakan pendekatan saintifik pada pembelajaran fisika, karena pengarahan dari kurikulum 2013 yang mengharuskan para peserta didik dapat mengembangkan keterampilan berpikir kritis, aktif, kreatif, dan berinovasi atau berkarya. Guru tidak hanya fokus menjelaskan materi pembelajaran, tetapi juga fokus pada pengalaman belajar peserta didik yang memuat kegiatan berupa mengamati, menanya, mengumpulkan informasi (mencoba), menalar (mengasosiasi), dan mengkomunikasikan. Pendekatan saintifik dapat diarahkan pada kegiatan pembelajaran yang berbasis pemecahan masalah dan pembelajaran berbasis proyek.
Valoración del proceso formativo ambiental del estudiante de arquitectura. Universidad de Camagüey, Cuba
Authors: Martínez moreno Aldo Raudel , Treviño Cubero Arnulfo , Banda Muñoz Fernando
Published: January 2024

El proceso formativo en la Educación Superior se ha transformado en función de las necesidades sociales. En particular, la formación ambiental, ha estado intencionada desde la concientización como proceso reflexivo en el contexto educativo, acompañada por la búsqueda de soluciones a problemáticas causadas por la transgresión del hombre al medio.

En la carrera de Arquitectura, se garantiza desde el proceso docente-educativo, la trascendencia del compromiso de los estudiantes con su entorno en correspondencia con las necesidades del desarrollo en los territorios. Desde el proceso de perfeccionamiento de los Planes de Estudios, se aboga por el acercamiento a las exigencias socioeconómicas del país sobre la base de alcanzar una formación y desarrollo profesional con responsabilidad ética, social y ambiental.

El texto, tiene la intención de valorar el proceso formativo ambiental de la especialidad en la Universidad de Camagüey a partir del diseño de una estrategia educativa que facilite este fin. Se emplea el método de análisis y síntesis, e inducción-deducción en la aproximación al estado del arte, el estudio y la crítica de fuentes en los sustentos teóricos, y el método Delphi para la valoración del diseño de la estrategia.
Ciudad metropolitana y crecimiento expansivo.
Authors: Sousa-González Eduardo
Published: January 2024

Desde la teoría es posible circunscribir la génesis de los procesos expansivos en las ciudades y las ciudades metropolitanas del sur global y seguramente del mundo conocido, desde dos transformaciones evolutivas que se gestan en su territorio particular, esta metamorfosis espacial está directamente vinculadas a lo que en esta investigación denominamos como ensanches periféricos; dichas extensiones espaciales en las zonas urbanas se han identificado con dos formas evolutivas que aquí denominamos como: i. Ensanches periféricos de origen y ii. Ensanches periféricos de proceso. Aquí la pregunta a responder sería: ¿Cuál y cómo sería la formación de estos dos tipos de bordes periféricos en las ciudades?
Oncoplastic surgery for Paget’s disease of the breast
Authors: Vieira René Aloisio da Costa , Pelorca Rafael José Fábio , Oliveira-Junior Idam de
Published: January 2024

Objective: Paget’s disease of the breast (PDB) is a rare nipple entity associated with multifocality. Due to its location, it is necessary to resect the nipple-areolar complex. For surgery, central quadrantectomy, and for mastectomy was the treatment in the past. The feasibility of performing oncoplastic breast surgery (OBS) for PDB is unknown. The objective of this study was to evaluate the feasibility of oncoplastic surgery for Patet’s disease of the breast. Methodology: This retrospective study was approved by the institutional Research Ethics Committee under numbers 657293 and CAAE 31046314.5.0000.5437. Patients with PDB treated at a tertiary cancer hospital between 2000 and 2021 were evaluated. We evaluated the factors related to the performance of OBS in PDB. In addition, the impact of OBS on local recurrence and survival was analyzed. Comparisons were made between groups using the chi-square test, Mann-Whitney U test, and Kaplan-Meier method. To assess the impact factor of the variables on the performance of OBS, logistic regression was performed. Results: A total of 85 patients were evaluated. OBS was performed in 69.4% (n=59), and of these, 16 (27.2%) were symmetrized with a contralateral surgery. Mastectomy without reconstruction was performed in 28.3% of the patients. The main procedure performed was mastectomy with reconstruction (44.7%), and the preferential technique for immediate reconstruction was skin sparing mastectomy with prosthesis, and for late reconstruction, latissimus dorsi. BCS was performed in 27.0%, mainly with plug-flap technique (OBS). Age was associated with the use of OBS, wherein patients aged 40–49 years were associated with a higher rate of OBS (p=0.002; odds ratio 3.22). OBS did not influence local recurrence (p=1.000), overall survival (p=0.185), or cancer-specific survival (p=0.418). Conclusion: OBS improves the quality of surgical treatment in PDB without influencing local recurrence or survival.
Follow-up of a Li-Fraumeni syndrome case
Authors: Nobrega Gabriela Bezerra , Küller Marina Bellatti , Rios Gabriela Marçal , Maesaka Jonathan Yugo , Filassi José Roberto
Published: January 2024

Introduction: Li-Fraumeni syndrome (LFS) is responsible for about 1% of hereditary breast cancers (BC). We present a case report of a young woman with synchronous osteosarcoma and BC. Case Report: NOB, 23 years old. Mother died with BC at 36 years old and sister died due to neuroblastoma at 2 years old. She was referred in 2021 for a nodule in her left breast and the ultrasound results showed an irregular nodule of 1.5×1.2×1.3 cm BI-RADS®5 and anatomopathological invasive carcinoma of non-special histological type (NST), estrogen receptor 80%, progesterone receptor 100%, Her2 negative, and Ki67 60% cT1N0. It was associated with a lesion in the alveolar mucosa with bleeding and deformity of the oral cavity with anatomopathological high histological osteosarcoma-T1N0. Surgical treatment was performed: maxillectomy of meso and bilateral infrastructure+tracheostomy+reconstruction with microsurgical flap of the fibula and, then, left adenomastectomy+sentinel lymph node biopsy+prosthesis reconstruction. Surgical anatomopathological results in central/medullary high-grade conventional osteosarcoma chondroblasts 7.3×6.1×3.9 cm, free surgical margins and four cervical lymph nodes free of neoplastic involvement, and invasive breast carcinoma NST with medullary characteristics 1.8×1.3 cm, free margins, and absence of metastasis in two sentinel lymph nodes –pT1pN0. Genetic test resulted in pathogenic mutation TP53 gene, position chr17:7.674.257, consequence p.Tyr236HisENST00000269305. Adjuvant chemotherapy was docetaxel+cyclophosphamide. Two years after treatment, she is taking tamoxifen, scheduled for contralateral adenomastectomy, and maintains high-risk follow-up. There is no signal of any cancer disease. Discussion: LFS is an autosomal dominant inheritance of high penetrance. The diagnosis is based on the identification of a pathogenic variant in the TP53 gene. It is related to several tumors diagnosed at an early age. BC is the most common cancer and affects 27–31% of patients. Osteosarcoma corresponds to 3%–16% of cases, usually occurring before the age of 30 years. The prognosis of patients does not differ from those with sporadic cancer. They must be monitored by a multidisciplinary team, screening with annual whole body/breast MRI and mammography, and colonoscopy every 5 years. Genetic counseling is essential.
Epidemiological and histo-molecular profile of patients with breast cancer who underwent genetic testing at a tertiary clinic in northeastern Brazil
Authors: Carvalho Débora Medeiros de , Diocesano Kamila Bezerra Fernandes , Vieira Sabas Carlos , Cruz Maysa Gabriela Costa , Martins Fernanda Jorge , Sousa Camila Holanda de , Santos Nívya Emanuele Vilarinda dos
Published: January 2024

Objective: The aim of this study was to describe the epidemiological and histo-molecular profile of patients with breast cancer (CAM) who underwent genetic testing at an oncology clinic in northeastern Brazil. Methodology: This is a retrospective cohort study on patients with CAM who underwent genetic testing from 1998 to 2022 at a tertiary clinic in northeastern Brazil and who underwent multigene panel testing for hereditary cancer predisposition syndromes. Results: Data were collected from 208 patients, of which 122 had CAM. Of these, 14.75% were BRCA1, 11.47% were BRCA 2, 15.57% were VUS, 4.09% were other high penetrance mutations, and 54.12% did not have mutations. The most prevalent histological type was non-special carcinoma (42.62%) and the second was carcinoma in situ (37.70), 3.27% micropapillary, 5.73% lobular, and 0.81% inflammatory. The most prevalent molecular type in the sample was HER 2 (44.26%), and triple-negative was the second most prevalent (16.39%), 40% corresponding to luminal HER 2 and luminal. However, among the BRCA 1 and 2 mutations, the most prevalent molecular type was the triple-negative (34.37% of a total of 32 BRCA 1 and 2). The age with the most prevalent CAM was the range of 35–45 years with 32.78%. In addition, 99% of the patients were female and 1% were male (only one male), 43.4% of the tumors were grade 2, and 55.73% of the lymph nodes were not involved, with 17.2% of the only 1 affected lymph node. Conclusion: It is concluded that the most significant mutations are in the BRCA 1 and 2 genes with the triple-negative molecular type being the most prevalent in these genes, showing that the results corroborate the data already existing in the literature, as well as the importance of the genetic panel for the best individualization and optimization of treatments.
Male breast cancer: How to optimize the diagnosis?
Authors: Ribeiro Laíse Alves , Camargo João Victor Monteiro de , Galli Alexandre Pelícolla , Resende Geovana Sousa , Santos Daiane Rosa Dantas , Aranha Carlos Eduardo Nunes
Published: January 2024

Objective: Male breast cancer (MaBC) is a rare disease that represents about 1% of all cases of breast cancer (BC) in Brazil. The scarcity of screening campaigns hinders early diagnosis, directly affecting treatment and prognosis. Therefore, this study aimed to increase the visibility, among health professionals, for the aforementioned disease, describing how screening and diagnosis have been performed until now. Methodology: This study is a systematic literature review. Articles indexed in the electronic databases PubMed, SciELO, and ScienceDirect were collected. Studies were selected using the following descriptors and keywords: (Breast Cancer) AND (Men). Results: The avoidance of medical services by men, the absence of guidelines for the management of MaBC, and the rarity of this disease contribute to late diagnosis. The average delay in diagnosis ranges from 6 to 10 months after the onset of symptoms, and about 40% are diagnosed in stages III and IV. Clinical and radiological evaluation and tissue biopsy are essential for diagnosis. Screening should be initiated by evaluating risk factors, such as advanced age, radiation therapy, obesity, hormone imbalance, and BRCA2 mutations. The main clinical finding is a single, retroareolar, and painless mass, usually in the left breast. It can involve axillary lymph nodes, and, in rarer cases, nipple retraction, papillary discharge, and ulceration can be found. Mammography in men is generally more sensitive than in women. For biopsy, core biopsy is the preferred method. Conclusion: Despite its rarity, the MaBC mortality rate is higher than women BC. That may be due to unawareness of the disease among patients and lack of guidelines, possibly leading to medical negligence. Hence, careful attention to breast complaints, especially in highrisk patients, is mandatory to avoid late diagnosis. Promoting public awareness about MaBC and its symptoms is also required. Furthermore, the development of guidelines for diagnostic purposes would improve the management of MaBC.
Characterization of chronic pain in women undergoing breast cancer treatment
Authors: Andrade Hadirgiton Garcia Gomes de , Rahal Rosemar Macedo Sousa , Soares Leonardo Ribeiro , Oliveira Luis Fernando de Pádua , Lemos Nayara Alves de Freitas , Corrêa Rosangela da Silveira , Conde Délio Marques , Freitas-Júnior Ruffo
Published: January 2024

Objective: The objective of this study was to characterize chronic pain in women undergoing surgical treatment for breast cancer. Methodology: This is a transversal study of quantitative and qualitative basis. Data collection was performed at a tertiary breast cancer treatment center located in central Brazil. We used the McGill Pain Questionnaire structured pain assessment questionnaire in its Brazilian version (BR – MPQ) and the Visual Analog Scale (VAS). Results: A total of 99 patients were interviewed, of which 46 were included in the study. Notably, 30 (65.2%) patients underwent quadrantectomy for surgical treatment of breast cancer. A type of breast reconstruction technique was used in 26 (56.5%) patients, most of them immediately. Sentinel lymph node biopsy was performed in 45 (97.8%) patients, but 22 (47.8%) required axillary lymphadenectomy for some oncological reason. Notably, 35 (76.0%) patients underwent neoadjuvant or adjuvant chemotherapy, and 40 underwent radiotherapy (87.0%). We observed a predominance of intermittent and pulsating pain, with a mean intensity of 5.5 on the VAS. In the McGill questionnaire, a total score of 28.24 (±14.51) was observed. All participants had chronic pain of the intermittent type, starting after surgery, located in the surgery scar and in the ipsilateral arm. The sensory domain contributed the most to pain perception, with an average of 16.83 (±7.52). The pain assessment category was reported by 41 (89.1%) patients, followed by the sensitive (n=15; 32.6%), miscellaneous (n=14; 30.4%), and affective (n=12; 26.1%). Chronic pain was predominantly characterized as pulsating, throbbing, sensitive, punishing, and strong. According to the VAS, the average intensity reported was 5.52 (±2.61). Conclusion: Our study characterized chronic pain in women undergoing surgical treatment for breast cancer, which may help identify and manage this symptom.
Radiotherapy and breast cancer: The risks of malignancies secondary to breast cancer treatment in patients with Li-Fraumeni syndrome
Authors: Ferreira Rubens Rezende , Queiroz Luan Almeida Japiassu de Freitas , Medeiros Sabrina Rocha , Santos Sara Leite Lira , Gioia Carolina Gabriela Divino Soares , Fernandes Victor Filipi Lemes , Azevedo Fernando Santos , Campedelli Ana Flávia de Paula G.
Published: January 2024

Objective: This study aimed to highlight the risks of malignancy induced by radiotherapy in the treatment of patients with breast cancer with Li-Fraumeni syndrome. Methodology: To this end, a literature review was carried out in the PubMed scientific database, using the descriptors: “Li-Fraumeni syndrome,” “TP53 gene,” and “Malignancies secondary to radiotherapy,” and as inclusion criteria, it was used: works in Portuguese and English, not duplicated and between the years 2016–2023, with the intention of using the most recent sources for the search result. Results: DNA damage by ionizing radiation is the main mechanism of radiotherapy action; therefore, disturbances in DNA repair can result in increased sensitivity to cancer treatment recessive radiosensitivity, for example, in patients with Li-Fraumeni syndrome. This is an autosomal dominant inherited disease that is usually associated with abnormalities in the P53 tumor suppressor protein (TP53) gene, located on chromosome 17p13. That said, the risk of malignancies correlates with the type of TP53 germline pathogenic variant, with the TP53 p.R337H mutation being particularly prevalent in Brazil. According to a published study in the journal Breast Cancer Research and Treatment, the risk of radiation-induced malignancy associated with Li-Fraumeni syndrome was higher for sarcoma and thyroid cancer in 12% of patients studied. Conclusion: Thus, when initiating radiotherapy treatment, early molecular diagnosis, with the intention of finding the Li-Fraumani syndrome, and careful assessment of the risks and benefits of treatment are essential for these patients, considering that the physician must always care for the well-being of the patient and, above all, do not cause harm to the patient.
STUDY OF SOIL STRATIFICATION IN LANDSLIDE AREAS ON BANTUAS ROAD USING THE RESISTIVITY GEOELECTRIC METHOD
Authors: Haryono Arif , Supriyanto Supriyanto , Djayus Djayus , Mislan Mislan , Lepong Piter , Abbas Asri Yana Pratama
Published: January 2024

A landslide is a natural disaster that often occurs in the Palaran sub-district, Samarinda, East Kalimantan. This sub-district with an area of ​​221.29 km2 is considered strategic as a buffer area for the National Capital City (IKN). Construction of toll roads, ports, factories, and housing has begun to be carried out here. However, in Palaran there are still many roads damaged due to landslides, one of which is Bantuas Road. To study soil stratification on the Bantuas Road section, research has been carried out using the dipole-dipole configuration of the resistivity geoelectric method. The data acquisition process was carried out at two locations, namely at the first landslide (STA 7+150) and the second landslide (STA 9+450), with each location consisting of three lines. The data processing uses Res2Dinv software to produce a two-dimensional model. Based on the resulting model, it is known that the landslide area at STA 7+150 is at a distance of 48 to 96 meters with the slip area at a depth of around 11 to 12 meters. Meanwhile, at STA 9+450, the landslide area occurred at a distance of 48 to 80 meters with the slip area at a depth of 8 to 10 meters. The slip area in the first landslide is interpreted to have occurred at the contact area between unconsolidated material and dense sand, while in the second landslide, it occurred at the contact area between weak silty sand and dense sandy clay.
Menggali Kearifan Lokal: Pendidikan Nilai Dalam Permainan Tradisional Suku Sasak
Authors: Muliadi Erlan , Asyari Akhmad
Published: January 2024

Traditional games of the Sasak tribe are an integral part of local wisdom and the culture of the Lombok community. However, currently, interest in these traditional games has declined, especially among children. This research aims to unearth local wisdom through the values education embedded in traditional Sasak tribal games. The research method involves introducing traditional games to children through direct play activities, enabling them to understand the meaning and values inherent in each game. Data collection techniques include participatory observation and interviews with traditional players and local community figures. The collected data are analyzed using a qualitative approach, detailing the moral, cultural, and social values found in traditional games. The results show that traditional games of the Sasak tribe encompass values of local wisdom, including team solidarity, precision, and a sense of responsibility. The implications of this research underscore the importance of preserving and integrating traditional games into values education as a means to conserve local culture and shape the character of children by appreciating the noble values of local traditions. This research is expected to make a positive contribution to the preservation of local wisdom and values education amid the ongoing tide of globalization.
The Effect of Liquid Organic Fertilizer of Shallot Skins and Compost of Coconut Dregs on the Growth of Mint Plant (Mentha piperita L.) Cuttings
Authors: Shahra Farah Diba , Jayanthi Sri , Atmaja Teuku Hadi Wibowo
Published: January 2024

Mint (Mentha piperita L.) belongs to the Lamiaceae family, whose essential oil is used as a flavouring agent and to treat diseases. The low productivity of mint plants is because the nutrients in the planting medium do not support growth efforts made through fertilization. Two organic materials that can be used as fertilizer are shallot skin and coconut dregs. This study aimed to determine the effect of liquid organic fertilizer on shallot skins and coconut dregs compost and the most optimal treatment for the growth of mint plant cuttings (Mentha piperita L.). This type of research was quantitative with an experimental method using a completely randomized design (CRD) factorial consisting of 2 factors, namely red onion skin liquid organic fertilizer and coconut dregs compost, each consisting of 3 levels so that the treatment combination consisted of 9 treatments with as many repetitions as three times. Data analysis in this study used the Kruskal Wallis test with SPSS. The results showed that it had a very significant effect on wet weight and a significant effect on the number of leaves on the growth of mint cuttings (Mentha piperita L.). The best treatment for each observation parameter was wet weight BM1AK2 (13 grams), number of primary branches BM1AK2 (2.67), plant height BM2AK1 (26.5 cm) and number of leaves BM2AK1 (27.33 strands).
Exploring OsHAK Transporters for the Salt Responsiveness in Rice
Authors:   1Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, TNAU, Coimbatore- 641003, Tamil Nadu, India, Balachandra Akshara , Shanmugam Varanavasiappan ,   1Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, TNAU, Coimbatore- 641003, Tamil Nadu, India, K Krish Kumar ,   1Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, TNAU, Coimbatore- 641003, Tamil Nadu, India, Veerasamy Ravichandran ,   2Department of Crop Physiology, TNAU, Coimbatore- 641003, Tamil Nadu, India, Easwaran Kokiladevi ,   1Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, TNAU, Coimbatore- 641003, Tamil Nadu, India, Duraialagaraja Sudhakar ,   1Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, TNAU, Coimbatore- 641003, Tamil Nadu, India, Loganathan Arul ,   1Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, TNAU, Coimbatore- 641003, Tamil Nadu, India
Published: January 2024

Environmental stresses are the major constraint in crop growth and productivity, particularly in rice. Improving rice against major abiotic stressors such as salinity is one of the major thrust areas. In this direction, the trait of sodium exclusion was the primary focus among the rice breeders to enhance salt tolerance. Along similar lines, increased uptake of potassium, the counter ion of Na+, through high-affinity potassium transporters (HAK) assumes significance in the context of maintaining a favorable Na/K ratio, a low Na/K is an indicator of salt tolerance. The OsHAK family in rice includes 27 members and an insight into the evolution, structure, and expression through in silico approaches was attempted. Phylogenetic analysis exhibited four distinct groupings of the OsHAK family, and functional motif analysis revealed a characteristic consensus sequence among the OsHAK transporters. Relative gene expression analysis based on published microarray data put forth the differential regulation of OsHAK3 X2, OsHAK8, OsHAK14(X2), OsHAK15 and OsHAK26 between salt-tolerant landrace Pokkali and susceptible cultivar IR29 and their tissue-specific expression profiles predicted. This study narrowed down a set of putative OsHAKs from the larger family for their role in enhancing cellular potassium under salt stress thus paving the way for crop improvement.
Histórias e ofícios de professore(a)s
Authors: Silva Carlos Eduardo da , Silva Daianne Severo da , Nascimento Danilo Rodrigues do , Areal Emilly Ganum , Santiago Joely Coelho , Loureto Márcia Barroso , Lima Maria Ana da Silva Morais , Carvalho Mário Sérgio Silva de , Amorim Risonete Gomes , Pessoa Valda Inês Fontenele
Published: January 2024

Esta obra representa parte da culminância de estudos realizados na disciplina Cultura, educação e práticas educativas, articulada ao Programa de Pós-Graduação em Letras: linguagem e identidade. Por um semestre letivo, nas tardes/noites das quartas-feiras, o grupo de professore(a)s, vinculados ao programa de doutorado e mestrado, com a leitura do material já realizada, reunia-se para o debate e articulação das suas experiências de formação e atuação docente com os textos estudados. Episódios importantes e bastante significativos para o campo da educação foram evidenciados nas discussões, o que gerou a ideia da escrita das narrativas para reuní-las em uma coletânea passível de publicação e que ora se apresenta.
Por representar as experiências reflexivas desse grupo de professore(a)s, pela importância do que falam sobre o que fazem e vivenciam cotidianamente, pela relevância da culminância dos estudos propiciados pelo curso e pelo o que pode ecoar nos futuros leitores é que a coletânea foi organizada. As narrativas dos dez autores refletem descontinuidades de verdades teóricas que já não tem significância para os espaços-tempos de atuação dos narradores; evidenciam a complexidade da formação e atuação docente; salientam as diferenças entre o desenvolvimento da docência nas instituições públicas e privadas; destacam errâncias, existências e (re)existências do fazer professoral; demonstram a centralidade da cultura nas práticas formativas, como também, a pluralidade cultural presentes nos espaços-tempos escolares; ressaltam os labirintos dos espaços educativos institucionalizados e ressignificação da prática docente.
CONHECIMENTO ACERCA DO USO DE GLUCAGON PARA HIPOGLICEMIA SEVERA EM PACIENTES COM DIABETES TIPO 1
Authors: Witte Bruna Rambo , PISANI RENAN BRUNO FARIA , Lucena Pietra Ambrósio Loyola de
Published: January 2024

Introdução: A injeção de resgate de glucagon é o principal tratamento extra-hospitalar para a hipoglicemia severa, é seguro e eficaz, porém é pouco conhecido por pacientes e cuidadores de pacientes com diabetes mellitus tipo 1. Materiais e métodos: estudo de corte transversal realizado com amostra de 1062 pessoas divididas entre cuidadores de pacientes com diabetes tipo 1 e portadores de diabetes tipo 1. Discussão e conclusão: apesar do conhecimento acerca da utilização do uso dos kits de resgate de glucagon, a minoria dos pacientes e cuidadores de pacientes com DM1 sabem sua função e importância para um tratamento eficaz e seguro da hipoglicemia severa. Ademais, dentre as pessoas que conhecem o kit, a minoria o possui, sendo que o número de pessoas que o teriam consigo em um momento de necessidade é mínimo. É importante ressaltar que nos dois grupos avaliados, cerca de 90% das pessoas não tinham experiência ou treinamento para o uso das injeções de glucagon, de modo que mesmo com o kit em mãos, não seria possível administrá-lo.
Seasonal Variability of Rainfall and Thunderstorm Patterns in Kenya
Authors: Kurgat Mary , Gitau Wilson
Published: January 2024

This paper presents an analysis of spatial and temporal variation of rainfall and thunderstorm occurrence over Kenya from January 1987 to December 2017. The meteorological data used were obtained from the Kenya Meteorological Department (KMD) for the same period. This included the monthly thunderstorm occurrences and rainfall amounts of 26 synoptic stations across the country. The characteristics of monthly, seasonal and annual frequency results were presented on spatial maps while Time series graphs were used to display the pattern for annual cycle, seasonal variations and the inter-annual variability of rainfall amounts and thunderstorm occurrences. A well-known non-parametric statistical method Mann Kendall (MK) trend test was used to determine and compare the statistical significance of the trends. Thunderstorm frequencies over the Eastern, Central and Coast regions of the country showed a bimodal pattern with high frequencies coinciding with March-April-May (MAM) and October-November-December (OND) rainy seasons. Very few thunderstorm days were detected over June-July-August (JJA) season. The areas to the western part of the country, near Lake Victoria, had the highest thunderstorm frequencies in the country over the three seasons: MAM, JJAS and OND. The annual frequency showed a quasi-unimodal pattern. These places near Lake Victoria showed significantly increasing thunderstorm trends during the MAM and OND seasons irrespective of the rainfall trends. This shows the effects of Lake Victoria over these areas, and it acts as a continuous source of moisture for thunderstorm formation. However, most stations across the country showed a reducing trend of thunderstorm frequency during MAM and JJA seasons. The importance of these findings is that they could support various policy makers, and users of climate information, especially in the agriculture and aviation industries.
Corporate social responsibility and Indian healthcare sector: An analysis
Authors: CL Avadhani
Published: January 2024

Mahatma Gandhi, the father of the nation mentioned that, “There is enough on this planet for every one’s but not for everyone’s greed” In the words of our beloved present Prime Minister Narendra Modi ji, “Development has to be achieved collectively and it has to be quick paced and inclusive”. Naveen Jindal, Chairman Steel and Power limited once said, “A nation’s real strength not just its economy, but the health and happiness of its citizens.” The above three quotes are important because the development of the country is very essential, provided it should not harm the society, wholesomeness or goodness of nature. In addition Economic Growth and Development, there must exist a sustainable society and it is not necessary that only Government should take care of all these things but these Corporate Houses and the Private Sector should equally take the responsibility for the development of the country and society in particular to increase Healthcare awareness through CSR activities by increasing the funding through CSR Financial Investment. Corporate Social Responsibility though is a leading promoter of Education and Health in India after the amendment of Companies Act to make it mandatory to any Corporate Houses enjoying continuously three years of profiting to spend 2% of their profits under CSR activities. Spending of CSR funds on healthcare though much less the impact of it on the society is much more. It means Corporate House’s spending CSR funds on better health systems, facilities to the people will benefit the society as a whole. Corporate Houses such as healthcare facilities, pharmaceutical industries, health insurance companies involvement in social activities through CSR funds will have more impact as these people are having greater understanding of the subject. Some of the activities such as safety norms in healthcare improving healthcare to the down trodden in the society are laudable. In written Corporate Houses who spent money through CSR activities are given tax exemptions by the government and thus will raise good will in the society and a boost in their marketing activities.
The impact of quality of life and oral hygiene in type 2 diabetes mellitus patients
Authors: Aurelia Della Imani  , Mirza Khairina  , Gilang Ratri Sakti  , Indeswati Diyatri
Published: January 2024

Background: 90-95% improvement which happens frequently and common cases is type 2 diabetes mellitus caused with increased blood glucose through degradation of insulin release by the pancreatic gland. Quality of sufferers life with type 2 diabetes mellitus isn’t decided by general health but also by dental and oral health. Purpose: To determine quality of life and oral hygiene conditions in sufferers against type 2 diabetes mellitus. Methods: This ​research using literature study from several research journal databases published in 2015-2023. Literature search use a strategy with criteria of type 2 diabetes mellitus, oral hygiene, and quality of life utilize Pubmed, Google Scholar, Science Direct, and Elsevier databases with article title criteria discuss the relationship between influences quality of life and oral hygiene in sufferers against type 2 diabetes mellitus. Results: There are respondents who have minimal knowledge about type 2 diabetes mellitus associated with dental and oral health in several studies. Majority of the female sufferers through type 2 diabetes mellitus. This disease related to the oral cavity causes pain and physical discomfort has negative effects on quality of life. Bacteria increase in the oral cavity and decrease saliva flow which causes xerostomia and decreases self-cleaning effect which can interfere with oral hygiene. Person with diabetes has higher effects of developing caries due to high levels of glucose in saliva. Conclusion: It's important for diabetes mellitus sufferers to always maintain their health status and oral hygiene.
Verification of the analytical performance of CA 19-9 assay on Abbott Alinity ci®: Experience of the central laboratory Mohammed VI Oujda
Authors: Sabah Mokhtari  , Amina Himri  , Loubna Yacoubi  , Soufiane Beyyoudh  , Dounia El Moujtahid  , El houcine Sebbar  , Mohammed Choukri
Published: January 2024

Introduction: CA19-9 is a marker used in the diagnosis and monitoring of several cancer diseases. The aim of this study is to evaluate the CA19-9 assay on the Abbott ALinity Ci automated system. This evaluation is part of an overall approach to verifying the methods used in the CHU's central laboratory, with a view to compiling an accreditation file in line with the requirements of standard NF EN ISO 15189. Materials and methods: The aim of our study was to evaluate the scope A criteria detailed in the guide to verification/validation of methods in Medical Biology, in accordance with the recommendations of standards NF EN ISO/CEI 17025, NF EN ISO 15189 and NF EN ISO 22870. Verification was carried out on the CA19-9 assay on Alinity® Ci, which uses the immunoassay technique Criteria (repeatability, reproducibility) were verified. Results: The results obtained show good repeatability for the 3 levels with respectively CV1=2,61% , CV2=2,78% , and CV3 =3,26% % and intra-laboratory reproducibility with CV1=3,98% , CV2= 3,16% and CV3 = 3,61%. Discussion and Conclusion: The central laboratory of our University Hospital is committed to a quality policy which includes a control approach for the various analytical systems used. The results obtained for the various CA19-9 assay verification criteria on our Alinity® Ci system, compared with data from the supplier, RICOS and learned societies, are satisfactory and verify analytical performance.
Psychometric Properties of the Oral Mucositis Daily Questionnaire in Turkish Children with Cancer
Authors: YILDIRIM Büşra Güliz , ÖZALP GERÇEKER Gülçin
Published: January 2024

Purpose: The Oral Mucositis Daily Questionnaire (OMDQ) can be used in pediatric cancer patients. This study aimed to investigate the Turkish validity and reliability of the OMDQ in children aged 8 - 18 years diagnosed with cancer at two university hospital pediatric hematology/oncology clinics.

Methods: Children’s International Mucositis Evaluation Scale (ChIMES) and the World Health Organization (WHO) Oral Mucositis Grading Scale were used in parallel form reliability. Thirty children with oral mucositis were included in the study at the inter-rater and test-retest reliability on the 14th and 15th days of chemotherapy treatment. Ninety-two children were included for the construct validity. Kappa Compliance Analysis, Spearman’s correlation coefficient, and Cronbach’s alpha were evaluated.

Results: The content validity index was calculated for the scores given by the experts and the items were changed between .90 and 1.00. On the 14th and 15th days of chemotherapy treatment, the correlation values for each item of OMDQ were found to be over .64. In the construct validity, the patients’ mean age was 11.7±3.3, and 46.7% diagnosed with Acute Lymphoblastic Leukemia. Cronbach Alpha value of OMDQ was .92. The OMDQ items showed a positive correlation with each other except for diarrhea questions. According to the WHO Oral Mucositis Grading Scale, 55.4% of the patients had grade 1 mucositis. The similar items of OMDQ and ChIMES had a positive significant relationship (p < .001).

Conclusion: The Turkish version of the OMDQ was a valid and reliable instrument in children aged 8 - 18 years diagnosed with cancer.
Comparison of Efficacy of Hyperthermic Intraperitoneal Chemotherapeutics Mitomycin C versus Oxaliplatin in Experimental Colorectal Peritoneal Metastasis Model
Authors: MANOĞLU Berke , CANDA Aras Emre , YAVUZŞEN Tugba , AKTAŞ Safiye , ALTUN Zekiye , YILMAZ Osman , BİŞGİN Tayfun
Published: January 2024

Aim: Our study aimed to establish a mouse model with colorectal cancer-induced peritoneal metastasis(PM) and to compare the efficacy of hyperthermic intraperitoneal chemotherapeutic agents, mitomycin C and oxaliplatin.

Materials and Methods: The peritoneal metastasis model was established in nude mice using the CC531 colon carcinoma cell line. Models with PM were randomized into four groups of seven animals each: Group-1, control group; Group-2, hyperthermic intraperitoneal chemotherapy(HIPEC) with mitomycin C(MMC), and Group-3, HIPEC with Oxaliplatin(OXA).

Results: Tumor development was achieved in all animals. While the tumor burden decreased significantly in the treatment Group-2(p=.013). In the PM mouse model, hyperthermic intraperitoneal administration of MMC had a higher tumoricidal effect than hyperthermic intraperitoneal administration of OXA.

Conclusions: Our PM model provided a good opportunity to examine the efficacy of HIPEC and IPIP. Hyperethermic intraperitoneal mitomycin applied in the colorectal PM animal model was found to have higher tumoricidal activity than oxaliplatin. In future studies, we plan to evaluate efficacies of different drugs in the PM models we have created.
The Needs Assessment of Training Course to Enhance the Lesson Study Process for Lecturers of Souphanouvong University, Lao PDR
Authors: Vathanavong Thongthiane , Tungkasamit Angkana , Thinwiangthong3 Sampan
Published: January 2024

The purposes of this research were: 1) to study the state of the problems of teaching and learning for lecturers; 2) to undertake a needs assessment for training to promote the lesson study process for lecturers; and 3) to compare the state of the problems and the needs assessment for training to promote the lesson study process.

The study sample comprised 54 administrators; 167 lecturers and 327 students from six faculties of Souphanouvong University who were selected by stratified random sampling. Mixed methods were used as the research methodology; an Embedded Design was conducted by studying quantitative methods and supplementing with qualitative methods. Research Instruments used to collect the data were a questionnaire and structured interviews. Statistics used included percentage, mean, standard deviation (S.D.) and Priority Needs Index Modified (PNIModified). T-test and One Way MANOVA was applied.

The research results were as follows: 1) The state of the problems of teaching and learning for lecturers, including the overall average, was medium; 2) A needs assessment of training to promote the lesson study process by all groups of the sample was an essential requirement for all items, with the overall average of 0.35; and 3) The state of the problems and needs assessment of training to promote the lesson study process, as classified by samples group, showed no difference in significance except for administrators and lecturers, which was different for the state of the problems at the .05 level of statistical significance.