bluuebunny/crossref_metadata_2025 huggingface dataset:
2019 novel coronavirus of pneumonia in Wuhan, China: emerging attack and management strategies
Authors: She Jun , Jiang Jinjun , Ye Ling , Hu Lijuan , Bai Chunxue , Song Yuanlin
Published: February 2020

An ongoing outbreak of 2019‐nCoV pneumonia was first identified in Wuhan, Hubei province, China at the end of 2019. With the spread of the new coronavirus accelerating, person‐to‐person transmission in family homes or hospitals, and intercity spread of 2019‐nCoV occurred. At least 40,261 cases confirmed, 23,589 cases suspected, 909 cases death and 3444 cases cured in China and worldwide 24 countries confirmed 383 cases being diagnosed, 1 case death in February 10th, 2020. At present, the mortality of 2019‐nCoV in China is 2.3%, compared with 9.6% of SARS and 34.4% of MERS reported by WHO. It seems the new virus is not as fatal as many people thought. Chinese authorities improved surveillance network, made the laboratory be able to recognize the outbreak within a few weeks and announced the virus genome that provide efficient epidemiological control. More comprehensive information is required to understand 2019‐nCoV feature, the epidemiology of origin and spreading, and the clinical phenomina. According to the current status, blocking transmission, isolation, protection, and alternative medication are the urgent management strategies against 2019‐nCoV.
Improvement of 40Ar/39Ar age determinations for Quaternary basaltic rocks by eliminating the peak suppression effect
Authors: Kim Jeongmin , Cho In-Hwa
Published: February 2020

Background

The peak suppression effect, which suppresses the argon isotope signal due to the incomplete cleaning of gas from geological samples during measurement, is found in volatile-rich samples using the ARGUS VI noble gas mass spectrometer and its sample preparation system. Such effect hampers getting the precise isotope ratio essential for the40Ar/39Ar age calculation.

Findings

The addition of one hot-getter and three room-temperature getters to the sample preparation system can effectively eliminate the peak suppression effect for several milligrams of sample during argon measurement to yield highly plausible40Ar/39Ar ages of Quaternary volcanic rocks.

Conclusions

The modified preparation system makes it possible to get highly precise zero-time isotope signals, and thereby a geologically plausible40Ar/39Ar age, especially for a small amount of volatile-rich samples.
Asymmetrical Bioimpedance in the Anterior Circulation for Urgent Stratification of suspected Stroke (ABACUS Stroke): study protocol for a diagnostic accuracy study
Authors: Price Christopher I. , Shaw Lisa , Dixit Anand , Graziadio Sara , Lendrem Clare , Mitra Dipayan , Rodgers Helen , Sutcliffe Lou , White Phil
Published: February 2020

Background

Early identification and treatment of stroke improve outcome. Ischaemic stroke due to large vessel occlusion (LVO) benefits from time-critical thrombectomy but this is only available in highly specialised healthcare services. Cerebral Bioimpedance Asymmetry (CBA) measurement obtained with the portable and rapid Cerebrotech Visor™ System device may be able to identify certain types of stroke including LVO. This test could be deployed pre-hospital and used to immediately direct patients to the most appropriate healthcare service for treatment. This study is evaluating the diagnostic accuracy of CBA measurements obtained from a real-world population of suspected stroke.

Methods

Study design: Prospective observational cohort study.

Setting: A hyperacute stroke unit and neuroscience centre in North East England.

Participants: Adults with a paramedic assigned diagnosis of suspected stroke arriving at hospital within 6 hours of symptom onset.

Index Test: Cerebral Bioimpedance Asymmetry measurement performed using the Cerebrotech Visor™ System. Measurement values produce continuous data (range 0 –100); pre-defined threshold for positive state ≥ 10.

Reference Standard Tests: Standard CT brain +/- CT/MR angiography, and expert clinician opinion will establish the following clinical outcomes which constitute the suspected stroke population: ischaemic stroke +/- large vessel occlusion; symptomatic severe anterior vessel stenosis; large (≥60ml) and small (<60mls) vessel intracerebral haemorrhage; transient ischaemic attack; stroke mimic conditions; prior territorial stroke.

Analyses: Sensitivity, specificity, negative and positive predictive values, area under the Receiver Operating Characteristic curve for identification of i) “complex stroke” (ischaemic stroke with large vessel occlusion or symptomatic severe anterior vessel stenosis or intracerebral haemorrhage ≥60ml or prior territorial stroke) and ii) ischaemic stroke with large vessel occlusion in isolation.

Sample size: 124 participants

Discussion

The results from this study will determine how accurately CBA measurement using the Cerebrotech Visor™ System can identify key stroke types within the suspected stroke population. Acceptable diagnostic performance would be an important step forwards for access to time-critical treatments.

Trial registration

Registered with ISRCTN (identifier: ISRCTN79169844) on 06/08/2018.
Long non-coding RNA HOTAIR and HOTTIP as potential biomarkers for hepatitis C virus genotype 4-induced hepatocellular carcinoma
Authors: Roshdy Fawzy , Farag Mohamed M. S. , El-Ahwany Eman , Mahmode Ola , Mousa Adel A. , El Talkawy Mohamed , Essawy Faiza
Published: February 2020

Background

Long non-coding RNAs (lncRNAs) homeobox (Hox) transcript antisense intergenic RNA (HOTAIR) and HOXA transcript at the distal tip (HOTTIP) have been suggested to be implicated in liver cancer tumorigenesis and progression; however, little is known about the role of the plasma HOTAIR and HOTTIP in liver cancer diagnosis and prognosis. The current study aimed at measuring the plasma levels of long non-coding RNAs (HOTAIR and HOTTIP) expression in chronic liver disease (CLD) due to HCV genotype 4 infection with/without cirrhosis and HCC patients in an attempt to evaluate the potential benefits of these new circulating as non-invasive diagnostic biomarkers and a novel therapeutic strategy for liver cirrhosis and carcinogenesis of Egyptian patients. Hundred subjects were included in this study, divided into two groups; group I (50 patients) were classified into subgroup Ia (CLD without cirrhosis, n = 25) and subgroup Ib (CLD with cirrhosis, n = 25), group II (CLD patients with HCC, n = 25), and control (healthy volunteer, n = 25). The expression of lncRNAs (HOTAIR and HOTTIP) genes was analyzed by real-time PCR.

Results

LncRNAs (HOTAIR and HOTTIP) showed upregulation in all diseased groups, which was in consistent with the progression of the disease toward the HCC stage. In addition, HOTAIR and HOTTIP showed a diagnostic ability to discriminate between cases of cirrhosis and HCC compared with healthy control (p < 0.001), while HOTAIR and HOTTIP did not show a discrimination significant differences between cirrhotic cases and non-cirrhotic cases. By using receiver operating characteristic curve (ROC) analysis, it was found that LncRNAs (HOTAIR and HOTTIP) could diagnose liver cancer with 64.0% sensitivity and 86.0% specificity and 48.0% sensitivity and 88.0% specificity. Furthermore, both genes can be considered as the predictor and prognostic parameters for cirrhosis (OR = 1.111, p = 0.05) and (OR = 1.07, p = 0.05) respectively, and HCC (OR = 1.047, p = 0.01) and (OR = 1.05, p = 0.003). The increased HOTAIR and HOTTIP expression were associated with advanced tumor stages and higher grades.

Conclusion

These results strongly prompt us that HOTAIR and HOTTIP genes can be used as non-invasive prognostic biomarkers and new therapeutic targets for HCV genotype 4-induced HCC.
The association of estrogen-signaling pathways and susceptibility to open-angle glaucoma
Authors: Ulhaq Zulvikar Syambani
Published: February 2020

Background

Glaucoma is a complex multivariate disorder characterized by retinal ganglion cell (RGC) loss and optic nerve degeneration. Evidence suggests the role of estradiol (E2) and the etiology of glaucoma. Therefore, this present study evaluates the association between estrogen-signaling pathways and the risk of open-angle glaucoma (OAG).

Results

Meta-analysis was performed from available studies that investigated intraocular pressure (IOP) in patients treated with or without hormone replacement therapy (HRT) and studies that evaluated the associations between estrogen receptor (ER) polymorphisms and the risk of OAG. The pooled result showed that HRT had a positive effect in lowering IOP. Moreover, ERβ polymorphisms showed a significant association with the risk of OAG.

Conclusion

This report supports the notion that estrogen-signaling pathways play a pivotal role in the development of OAG.
How the effective pore and grain shapes are correlated in Berea sandstones: Implications for joint elastic-electrical modeling
Authors: Han Tongcheng , Wei Zhoutuo , Li Fulai
Published: February 2020

Joint seismic-electromagnetic surveys are increasingly being used for understanding the subsurface. Valid rock-physics models are key for interpreting joint survey data. Such models should explore the cross-property relationship between the elastic and electrical properties and link the joint elastic-electrical correlations to the properties of various types of rocks of interest. However, although current differential effective medium (DEM) models have had great success in independently modeling the elastic and electrical properties of porous rock, they are not directly suitable for joint elastic-electrical modeling because the elastic and electrical DEM models describe the microstructures of the rocks in different ways. Based on dedicated laboratory measurements and theoretical modeling, we have investigated how the effective pore and grain shapes are correlated in two Berea sandstones. We determine that the effective pore aspect ratios inverted from the elastic properties exhibit a negative linear correlation with the effective grain aspect ratios obtained from the electrical inversion. The effective pore and grain aspect ratios are linked as an implicit function of varying porosity with confining pressure. Using the derived pore and grain shapes correlation, the joint elastic-electrical modeling results compared successfully with experimental data. The obtained results reveal the natural link between the effective pore and grain shapes in Berea sandstones and make the microstructures between the elastic and electrical models consistent.
An atlas of genetic correlations between psychiatric disorders and human blood plasma proteome
Authors: Cheng Shiqiang , Guan Fanglin , Ma Mei , Zhang Lu , Cheng Bolun , Qi Xin , Liang Chujun , Li Ping , Kafle Om Prakash , Wen Yan , Zhang Feng
Published: February 2020

Background.

Psychiatric disorders are a group of complex psychological syndromes with high prevalence. Recent studies observed associations between altered plasma proteins and psychiatric disorders. This study aims to systematically explore the potential genetic relationships between five major psychiatric disorders and more than 3,000 plasma proteins.

Methods.

The genome-wide association study (GWAS) datasets of attention deficiency/hyperactive disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BD), schizophrenia (SCZ) and major depressive disorder (MDD) were driven from the Psychiatric GWAS Consortium. The GWAS datasets of 3,283 human plasma proteins were derived from recently published study, including 3,301 study subjects. Linkage disequilibrium score (LDSC) regression analysis were conducted to evaluate the genetic correlations between psychiatric disorders and each of the 3,283 plasma proteins.

Results.

LDSC observed several genetic correlations between plasma proteins and psychiatric disorders, such as ADHD and lysosomal Pro-X carboxypeptidase (pvalue = 0.015), ASD and extracellular superoxide dismutase (Cu-Zn;pvalue = 0.023), BD and alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 (pvalue = 0.007), MDD and trefoil factor 1 (pvalue = 0.011), and SCZ and insulin-like growth factor-binding protein 6 (pvalue = 0.011). Additionally, we detected four common plasma proteins showing correlation evidence with both BD and SCZ, such as tumor necrosis factor receptor superfamily member 1B (pvalue = 0.012 for BD,pvalue = 0.011 for SCZ).

Conclusions.

This study provided an atlas of genetic correlations between psychiatric disorders and plasma proteome, providing novel clues for pathogenetic and biomarkers, therapeutic studies of psychiatric disorders.
Cancer Informatics for Cancer Centers (CI4CC): Building a Community Focused on Sharing Ideas and Best Practices to Improve Cancer Care and Patient Outcomes
Authors: Barnholtz-Sloan Jill S. , Rollison Dana E. , Basu Amrita , Borowsky Alexander D. , Bui Alex , DiGiovanna Jack , Garcia-Closas Montserrat , Genkinger Jeanine M. , Gerke Travis , Induni Marta , Lacey James V. , Mirel Lisa , Permuth Jennifer B. , Saltz Joel , Shenkman Elizabeth A. , Ulrich Cornelia M. , Zheng W. Jim , Nadaf Sorena , Kibbe Warren A.
Published: February 2020

Cancer Informatics for Cancer Centers (CI4CC) is a grassroots, nonprofit 501c3 organization intended to provide a focused national forum for engagement of senior cancer informatics leaders, primarily aimed at academic cancer centers anywhere in the world but with a special emphasis on the 70 National Cancer Institute–funded cancer centers. Although each of the participating cancer centers is structured differently, and leaders’ titles vary, we know firsthand there are similarities in both the issues we face and the solutions we achieve. As a consortium, we have initiated a dedicated listserv, an open-initiatives program, and targeted biannual face-to-face meetings. These meetings are a place to review our priorities and initiatives, providing a forum for discussion of the strategic and pragmatic issues we, as informatics leaders, individually face at our respective institutions and cancer centers. Here we provide a brief history of the CI4CC organization and meeting highlights from the latest CI4CC meeting that took place in Napa, California from October 14-16, 2019. The focus of this meeting was “intersections between informatics, data science, and population science.” We conclude with a discussion on “hot topics” on the horizon for cancer informatics.
Numerical simulations of electron cloud build-up in circular accelerators in the presence of multimode distribution beams
Authors: Cui X. , Gilardoni S. , Giovannozzi M. , Iadarola G.
Published: February 2020

Electron cloud effects have become one of the main performance limitations for circular particle accelerators operating with positively charged beams. Among other machines worldwide, the CERN Super Proton Synchrotron (SPS) as well as the Large Hadron Collider (LHC) are affected by these phenomena. Intense efforts have been devoted in recent years to improving the understanding of electron cloud (EC) generation with the aim of finding efficient mitigation measures. In a different domain of accelerator physics, non-linear resonances in the transverse phase space have been proposed as novel means of manipulating charged particle beams. While the original goal was to perform multi-turn extraction from the CERN Proton Synchrotron (PS), several other applications have been proposed. In this paper, the study of EC generation in the presence of charged particle beams with multimode horizontal distribution is presented. Such a peculiar distribution can be generated by different approaches, one of which consists in splitting the initial Gaussian beam distribution by crossing a non-linear resonance. In this paper, the outcome of detailed numerical simulations is presented and discussed.
TLR7 trafficking and signaling in B cells is regulated by the MHCII-associated invariant chain
Authors: Tohme Mira , Maisonneuve Lucie , Achour Karim , Dussiot Michaël , Maschalidi Sophia , Manoury Bénédicte
Published: February 2020

Toll-like receptor 7 (TLR7) is an endosomal receptor that recognizes single-stranded RNA from viruses. Its trafficking and activation is regulated by the endoplasmic reticulum (ER) chaperone UNC93B1 and lysosomal proteases. UNC93B1 also modulates major histocompatibility complex class II (MHCII) antigen presentation, and deficiency in MHCII protein diminishes TLR9 signaling. These results indicate a link between proteins that regulate both innate and adaptive responses. Here, we report that TLR7 resides in lysosomes and interacts with the MHCII-chaperone molecule, the invariant chain (Ii) or CD74, in B cells. In the absence of CD74, TLR7 displays both ER and lysosomal localization, leading to an increase in pro-inflammatory cytokine production. Furthermore, stimulation with TLR7 but not TLR9, is inefficient in boosting antigen presentation in Ii-deficient cells. In contrast, in B cells lacking TLR7 or mutated for UNC93B1, which are able to trigger TLR7 activation, antigen presentation is enhanced. This suggests that TLR7 signaling in B cells is controlled by the Ii chain.
Microalbuminuria (Moderate Albumin Excretion) and its relationship with Silent myocardial ischemia in treatment naïve type II diabetic patients
Authors: Hussain Qurban , Bukhari Mulazim Hussain , Afzaal Faiza , Fatima Wajiha
Published: February 2020

Objective: To determine the frequency of microalbuminuria (MAU) or Moderate Albumin Excretion (MAE) in treatment naïve type II diabetic patients and to compare the frequency of silent myocardial ischemia in treatment naive Type-II diabetic patients with and without microalbuminuria.

Methods: It was a cross sectional survey conducted in the outpatient Department, Jinnah Hospital Lahore, from 30th May 2015 to 29th November 2015. There were 227 patients, (consecutive treatment naïve type II diabetic patients), presenting to outpatient department were enrolled in the study. MAU/MAE, silent myocardial ischemia and effect modifiers like HbA1C > 7%, smoking pack years and dyslipidemia was determined. MAU/MAE was determined by urinary albumin excretion rate of 30-300 mg/24 hours and included patients underwent exercise tolerance test to diagnose silent myocardial ischemia.

Results: Out of total 165 patients (72.7%) were male and remaining 62 patients (27.3%) were female. The 54 patients (23.8%) had MAU/MAE. The 44 patients (19.4%) had silent myocardial infarction. When we cross tabulated microalbuminuria with silent myocardial infarction, result were significant. Out of 54 patients with MAU/MAE, 16 cases had silent myocardial infarction.

Conclusion: The frequency of microalbuminuria/ Moderate Albumin Excretion in treatment naïve type II diabetic patients was high and associated with the frequency of silent myocardial ischemia in treatment naïve type II diabetic patients with and without MAU MAU/MAE.

doi: https://doi.org/10.12669/pjms.36.3.938

How to cite this:Hussain Q, Bukhari MH, Afzaal F, Fatima W. Microalbuminuria (Moderate Albumin Excretion) and its relationship with Silent myocardial ischemia in treatment naïve type II diabetic patients. Pak J Med Sci. 2020;36(3):496-500. doi: https://doi.org/10.12669/pjms.36.3.938

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Reporting of academic degrees in high-impact medical journals
Authors: Stankovic Nikola , Nolan Jerry P. , Andersen Lars W.
Published: February 2020

Academic degrees following author names are often included in medical research papers. However, it remains unclear how many journals choose to include academic degrees and whether this is more common in certain types of journals. We examined the 100 highest impact medical journals and found that only 24 medical journals reported academic degrees. Moreover, this was substantially more common in journals based in North America compared with Europe. Further research is required to explore the implications of listing academic degrees on the readers’ attitude towards research quality.
Recent advances in iNKT cell development
Authors: Hogquist Kristin , Georgiev Hristo
Published: February 2020

Recent studies suggest that murine invariant natural killer T (iNKT) cell development culminates in three terminally differentiated iNKT cell subsets denoted as NKT1, 2, and 17 cells. Although these studies corroborate the significance of the subset division model, less is known about the factors driving subset commitment in iNKT cell progenitors. In this review, we discuss the latest findings in iNKT cell development, focusing in particular on how T-cell receptor signal strength steers iNKT cell progenitors toward specific subsets and how early progenitor cells can be identified. In addition, we will discuss the essential factors for their sustenance and functionality. A picture is emerging wherein the majority of thymic iNKT cells are mature effector cells retained in the organ rather than developing precursors.
Career guidance and socialization of students with complex disabilities
Authors: Tkacheva Viktoriya , Evtushenko Il'ya , Zhigoreva Marina
Published: February 2020

The textbook deals with theoretical and methodological, legal and socio-humanistic foundations of the system of vocational guidance and socialization of students with complex disabilities, the history of the formation of ideas about career counseling in domestic and foreign science and practice. Presented psycho-pedagogical features of pupils with complex disabilities and conditions that ensure successful mastery of the available professions, work skills. This description of the vocational diagnostic procedure aimed at exploring the possibilities of a child with severe to mastering the profession. The estimation of the level of employment, pre-vocational and vocational knowledge and skills. The possible extent of mastering different kinds of work, professional activities and employment options of persons with complex disabilities. First introduced the variative model of the system of vocational guidance and socialization of students with complex disabilities and the contents of psychological and pedagogical support of their families in the process of career guidance.
For students of institutions of secondary vocational education, undergraduate, master degree, post-graduate students studying in areas of training 44.03.01/44.04.01 "Pedagogical education", 44.03.02/44.04.02 "Psycho-pedagogical education", 44.03.03/44.04.03 "Special (defectological) education", as well as professionals working in the system, both General and special education, institutions secondary vocational and higher education.
Commentary to Chapter 8 of the Code of the Russian Federation about administrative offenses from December 30, 2001 № 195-FZ "Administrative offense in the sphere of environment protection and natural resources" (article by article)
Authors: Nozdrachev Aleksandr , Vasil'eva Mariya , Galinovskaya Elena , Gorohov Dmitriy , Zyryanov Sergey , Kalmykova Anastasiya , Kichigin Nikolay , Ponomarev Mihail , Sivakov Dmitriy , Shuplecova Yuliya
Published: February 2020

The commentary discusses the features of application of measures of administrative responsibility
for different types of offenses in the field of environmental protection, as well as in various fields of environmental management. Special attention is paid to the analysis of criteria of differentiation of the components of administrative offences and related criminal offences under the Criminal code of the Russian Federation. Taking into account all the changes and additions made to Chapter 8 of the Code of the Russian Federation on administrative offences as of November 1, 2019, are examples of administrative and judicial enforcement, as well as a synthesis and recommendations contained in the resolutions of the Plenum of the Supreme Court of the Russian Federation.
For practitioners - judges, prosecutors, environmental agencies, leading
proceedings for environmental offences, the police and other law enforcement agencies, attorneys, and administrative staff of business structures, experts of self-regulating organisations, academics, teachers, graduate students, undergraduates and law students and faculties.
Markets information and communication technology and sales organization
Authors: Naumov Vladimir
Published: February 2020

In the textbook sets out the basic information about the structure of markets, information and communication technologies (ICT), the methods of their research, assessing the attractiveness and forecasting, criteria and methods of segmentation. Deals with the organization of the sales Department of an IT company, involving analysis of organizational forms, population division, methods of remuneration and non-material incentives for experts dealing with sales of ICT products. Sets out the methodology for strategic sales of complex IT solutions, the technique of negotiation and the basics of neurolinguistic programming.
The textbook pays attention to the peculiarities of the sales and promotion of ICT products through the Internet, the possibilities of the use of CRM systems. The principles of the organization of partnerships with clients. This methodical approaches to the assessment of the efficiency of the sales Department of an IT company and its sales staff. Discusses the economic evaluation of the project implementation in selling IT solutions.
The textbook is prepared in accordance with the requirements of Federal state educational standard of higher education of the last generation.
Designed for students enrolled in training 38.03.05 "Business-Informatics", but it can be useful to students from other disciplines and practitioners working in the field of information and communication technologies.
Stadial analysis of lithogenesis
Authors: Yapaskurt Oleg , Karpova Evgeniya
Published: February 2020

The tutorial deals with modern methods stadial analysis which allows you to retroactively recreate the stages of the successive changes in the substance of sludge as its transformation into the breed and during the stay of the breed in stratisphere. Seems some of the techniques of deciphering and mineral structural and textural transformations, corresponding to different stages of lithogenesis and early metamorphism using optical and electron microscopy, as well as methods of synthesis of such observations on genetic (lithofacies and formational) basis, theoretical understanding of the mechanisms of multivariate processes of sedimentary rock formation, the problems of their classification and relationships with Genesis.
Meets the requirements of Federal state educational standard of higher education of the last generation.
For students of geological specialties, undergraduates, graduate students and research generalists.
EFFECTIVE INVESTMENT MODELS INDUSTRIAL INNOVATIONS AND THEIR COMPUTERIZATION
Authors: Arsen'ev Yuriy
Published: February 2020

The problems of investment design of industrial innovations related to the production and implementation of innovative products, modernization of labor productivity based on the project approach are investigated. Computer implementations of software modules for investment optimization methods in conditions of uncertainty and uncertainty that are part of the author's intellectual system for making management decisions are considered.
Court practice in the mechanism of legal monitoring
Authors: Glazkova Mariya
Published: February 2020

The manual discusses the role of judicial practice in the implementation of the mechanism of legal monitoring on the Federal, regional and local levels. It justifies significance of judicial practice as an integral part of the legal monitoring, since it is the judiciary, which is constant-
Janno being at the turn of sometimes conflicting interests to have the most complete information about the quality of legislation.
Describes the theoretical and normative foundations of legal monitoring, its organization and influence on the development of procedural law and the legal system. Special attention
given the anti-corruption monitoring.
The work is aimed at resolving issues of implementation of legal monitoring in the activities of public authorities, business-structures, public organizations and other civil society institutions in order to make informed proposals on optimization of the Russian legislation.
For deputies, employees of state and municipal authorities, representatives of civil society institutions, scientific workers, teachers, postgraduates and students of law universities and faculties.
Responsible for the laundering (legalization) of the proceeds of corruption under the legislation of foreign States
Authors: Vlasov Ilya , Vlasova Natal'ya , Golovanova Natalya , Kapustin Anatoliy , Cirin Artem
Published: February 2020

The risks of global and international regional (i.e. supranational) character associated with the extension of the economic and social base of terrorism and proliferation of weapons of mass destruction. Numerous studies demonstrate the close link between corruption and money laundering.
In this manual presents an analysis of international-legal regulation of responsibility for laundering (legalization) of the proceeds of corruption. Considered global, international instruments, documents of regional international organizations. Particular emphasis is placed on the institutional mechanisms of counteracting laundering (legalization) of the proceeds of corruption, which include international organizations involved in the establishment and implementation of international standards (FATF, world Bank, the Egmont group, Basel Committee, Wolfsberg group, regional fatfstyle, etc.).
For civil servants, employees of public organizations, scientists, teachers and graduate students, as well as for anyone interested in the issues of counteraction to laundering of proceeds of crime, financing of terrorism and corruption.
Régis Debray and the Latin American revolution of the XX century
Authors: Kolesov Mihail
Published: February 2020

The main task of the author is to give a broad picture of the main processes of the revolutionary movement in several countries of Latin America of the XX century continental historical context. The author used primarily the original (Spanish) sources, among which a special place belongs to works by the famous French writer Régis Debray (Regis Debray).
The book is intended for a wide audience, mainly for young people, for which the dramatic twentieth century already belongs to the annals of history.
Statistics in the management of socio-economic processes
Authors: Guzhova Oksana , Tokarev Yuriy
Published: February 2020

The manual contains theoretical material and the analysis of standard tasks and tests for the course "Statistics". The combination of theoretical and applied aspects will help students to organize independent work in the study of discipline and perform self-check when preparing for a competition or exam. The basic methods of statistical analysis: analysis of series of distribution and time series, index method, etc. are the basic statistical indicators used to describe socio-economic phenomena at the micro and macro level.
Meets the requirements of Federal state educational standard of higher education of the last generation.
For students enrolled in the bachelor courses "Management", "personnel Management" and "Economy".
Focus in Searching Core–Periphery Structures
Authors: Martignoni Dirk , Keil Thomas , Lang Markus
Published: February 2020

Organizations are often conceptualized as systems of interdependent choices that exhibit a core–periphery structure. Research is inconclusive, however, regarding whether organizations should focus their search efforts on their core or peripheral choices. In this paper, we seek to reconcile contradictory arguments and suggest that the efficacy of a search focus depends on the time horizon, environmental change, and how the core and periphery interact. In so doing, we demonstrate that the directionality of interdependence and whether interdependencies occur mostly within the core or between the core and periphery are key determinants of the implications of focus. We discuss the implications of our findings for various streams of research, including research on structural inertia and business model innovation.
Sobre amor, afeto e cidades
Authors: Camargo Paula De Oliveira
Published: February 2020

O texto foi escrito como um exercício de pensamento sobre a cidade enquanto ambiente vivido e de vivências, mas também como um exercício de escrita. A partir de textos de design e antropologia, buscou-se refletir sobre o tempo e suas sobreposições no ambiente urbano, bem como sobre a própria condição de ser na cidade. Através de imagens captadas com telefones celulares que mostram o chão da cidade do Rio do Janeiro, são formuladas correspondências entre amor, afeto e cidades.
A RELAÇÃO CIDADE-RAÇA-CAPITAL NO ESPAÇO URBANO CARIOCA: UMA ANÁLISE DAS REMOÇÕES NO PERÍODO PREPARATÓRIO PARA OS MEGAEVENTOS ESPORTIVOS
Authors: De Oliveira Natália Sales
Published: February 2020

O trabalho a que se propõe este artigo é analisar a remoção e a resistência no espaço urbano carioca com o esforço constante de observar a relação cidade-raça-capital. A análise se embasou em uma revisão de literatura sobre estudos e pesquisas sobre as remoções em período recente da história carioca: os preparatórios para os megaeventos esportivos. Primeiramente aborda-se o capitalismo contemporâneo, sua relação com o espaço e correlações da atual crise financeira com o espaço urbano carioca. Em segundo, recorta-se o objeto de análise trazendo o foco para os processos de remoção e resistência nos preparatórios dos megaeventos de 2014 e 2016, período posterior à crise econômica de 2007/2008 e momento em que os efeitos dessa crise eram intensos em todo o mundo. Após esta etapa, apresentam-se alguns estudos sobre algumas comunidades removidas procurando sempre centralizar a variável raça. Por fim, expõe-se uma das formas de resistência engendradas pela população atingida. Foi observado que a população se organizou em comitês populares, fóruns e associações em conjunto com pesquisadores e acadêmicos universitários; além da mobilização e uso político do Direito e de instituições estatais para combater a própria ação estatal de remoção. Conclui-se que limitar o estudo do espaço urbano à relação cidade-capital olvida a dupla opressão (de classe e raça) que pessoas não brancas podem sofrer na cidade. Além disso, conclui-se pela exigência por cidadania (o direito a ter direitos) pela população quando dos processos de resistência e uma certa esperança normativa no Direito durante este processo.
PETRÓLEO E EMPREGO: UMA ANÁLISE EM MUNICÍPIOS SELECIONADOS DO ESTADO DO RIO DE JANEIRO
Authors: Piquet Rosélia , Lumbreras Marlúcia Junger , De Castro Richard
Published: February 2020

A descoberta e exploração de petróleo nos reservatórios na camada do pré-sal ocasionou o deslocamento de investimentos da Bacia de Campos para a Bacia de Santos, e, consequentemente, provocou alterações no mercado de trabalho das regiões produtoras. Deste modo, o objetivo do presente texto é analisar o impacto do setor de petróleo no mercado de trabalho nos locais em que são desenvolvidas as atividades de Exploração e Produção (E&P), por meio da análise de um número equivalente de municípios confrontantes a ambas as bacias, durante o período compreendido entre os anos de 2000 até o presente. Foram consideradas informações referentes à população residente, aos postos de trabalho e ao nível educacional. O estudo indica que os municípios que abrigam equipamentos da indústria propriamente dita são os que apresentam os melhores indicadores quanto ao emprego e ao nível educacional. O estudo é concluído ressaltando que as transformações estruturais da geopolítica do petróleo tornam os prognósticos sobre a evolução do setor um terreno altamente movediço, embora sejam necessárias análises sobre cenários futuros.
DO MODERNISMO AO ALGORITMO: EVOLUÇÃO E PERSPECTIVAS DA POLÍTICA PATRIMONIAL BRASILEIRA
Authors: Erthal Thiago Serpa
Published: February 2020

Cultura é um termo de acepção ampla e, salvo se restrito em sua dimensão espacial e temporal, possui uma polissemia que dificulta sobremaneira sua conceituação. Daí porque, para entender a política pública de proteção do patrimônio cultural nas duas décadas do século XXI e as perspectivas futuras, é pertinente fazer uma investigação dos atores e premissas teóricas envolvidas na seleção dos bens materiais e imateriais a serem acautelados. Esse é o objetivo do presente artigo. Para alcança-lo, inicialmente se analisou a influência do pensamento modernista nas três primeiras décadas desde seu surgimento (1937-1967). Nessa chamada fase heroica, prevalecia a concepção dessa elite intelectual daquilo que deveria representar simbolicamente a cultura nacional. Em seguida, a aproximação do patrimônio cultural com o desenvolvimento econômico alterou significativamente os parâmetros de valoração e gestão. Diversos planos de financiamento se imbricaram diretamente com os critérios teóricos de seleção, influenciando-os e sendo influenciados numa complexa dinâmica de pensamento e ação. Nesse contexto, concluiu-se que uma das marcas da política pública patrimonial nas duas décadas do século XXI foi a relativa descentralização político-administrativa de sua execução, mesmo que com revezes. Por fim, propôs-se em perspectiva uma potencial migração desse protagonismo estatal – centralizado ou descentralizado – para as grandes empresas de tecnologia, em especial com a difusão da cultura dos algoritmos.
Transcatheter aortic valve implantation: Developing nursing practice
Authors: Gibbins Ann , Gannaway Alex , Parker Jessica , Hyde Kay , Brown Justine , Young Sarah
Published: February 2020

Transcatheter aortic valve implantation (TAVI) is a new clinical procedure used to insert an aortic valve percutaneously where conventional cardiac surgery would be deemed too high risk. When this procedure was introduced into the cardiac centre it was recognized that nursing practice would need to be developed for this new area of care. To address this a nursing care pathway was developed, spanning pre-procedure care, care in the cardiac catheter laboratory, post-procedure care and cardiac rehabilitation. In addition a patient information booklet was developed to provide patients with the necessary information in a consistent way. The development of this nursing practice will be discussed.
Stress and compassion fatigue in veterinary nurses in New Zealand
Authors: Harvey Laura C , Cameron Kristie E
Published: February 2020

Background:

Stress and compassion fatigue are widely acknowledged as prevalent in workers in ‘caring’ roles, however this has not been widely documented in New Zealand veterinary nurses.

Aim:

This project aimed to investigate the prevalence of stress and compassion fatigue in New Zealand veterinary nurses.

Method:

Using an online survey, veterinary nurses were asked to self-report their incidence of stress or compassion fatigue felt as a result of their working environment. Veterinary nurses were also asked to report the ways in which they cope with stress and compassion fatigue, and their likelihood of changing jobs.

Results:

There were 288 responses to the survey. Of these, 94% of respondents reported feeling stressed and 82% reported experiencing compassion fatigue as a result of their work. 30% of respondents reported an increase in the consumption of alcohol/cigarettes and drugs as a result of stress. Most respondents reported managing their stress and compassion fatigue by talking to colleagues or family. A large number of respondents reported having considered a career change at some stage due to stress or compassion fatigue.

Conclusion:

This research demonstrates a high incidence of stress and compassion fatigue in New Zealand veterinary nurses, with a low percentage of those seeking professional support. Further investigation into combatable causal factors for stress as it differs from compassion fatigue is warranted to ultimately offer support to veterinary nurses to continue their vocation.
Infographic: Can the oncology classification system be used for prosthetic joint infection?
Authors: Alt Volker , Rupp Markus , Langer Martin , Baumann Florian , Trampuz Andrej
Published: February 2020

Cite this article: Bone Joint Res. 2020;9(2):77–78.
Anti-Inflammatory Effects of Bee Venom on Phthalic Anhydride-Induced Atopic Dermatitis
Authors: Oh Myung Jin , Song Ho-Sueb
Published: February 2020

Background: Atopic dermatitis (AD) is a chronic inflammatory condition which can be studied using phthalic anhydride (PA) to induce AD. Anti-inflammatory properties of bee venom (BV) wereinvestigated to determine whether it may be a useful treatment for AD.Methods: AD was induced by applying to pical PA to 8-week-old HR-1 mice (N = 50), then treating with (0.1, 0.25, and 0.5 ?g) or without topical BV. Body weight, ear thickness histology, enzymelinked immune sorbent assay (serum IgE concentrations), Western blot analysis [inducible nitric oxide synthase, cyclooxygenase-2, IκB-α, phospho-IκB-α, c-Jun N-terminal kinase (JNK), phosphoJNK, p38, phospho-p38, extra cellular signal-regulated kinase (ERK), and phospho-ERK], and the pull down assay for immunoblotting (p50), were used to measure inflammatory mediators.Results: PA + BV (0.1, 0.25, and 0.5 μg) significantly decreased ear thickness without altering body weight. IgE concentrations decreased in the PA + BV (0.5 ?g)-treated groups compared with PAtreatment. Tumor necrosis factor-α, interleukin-1β, inducible nitric oxide synthase, cyclooxygenase-2, phospho-IκB-α, phospho-JNK, p38, phospho-p38, and phospho-ERK, all decreased following treatment with PA + BV compared with the PA-treatment alone. p50 was upregulated in the PA + BV-treated groups compared with the PA-treated group. Furthermore, the number of mast cells decreased in the PA + BV-treated groups compared with the PA-treated group. Epidermal thickness was significantly lower in the PA + BV-treated group compared with PA treatment alone.Conclusion: BV maybe a useful anti-inflammatory treatment for AD.
The Effect of Complex Korean Medical Treatment with Acupotomy on Irritable Bowel Syndrome: A Case Report
Authors: Min Baek Ki , Jin Joon Soo , Lee Do Eun , Shin Won Bin , Shin Jin Hyeon , Youn In Ae
Published: February 2020

The effects of complex Korean medicine treatment including acupotomy, on irritable bowel syndrome (IBS) are reported in this case study. A 54-year-old woman with diarrheal symptoms that alternatively improved and worsened for many years and worsening abdominal pain visited the emergency room and was diagnosed with IBS; she was admitted for approximately 2 weeks at the Acupuncture and Moxibustion Department of National Medical Center (NMC). Numerical rating scale (NRS), irritable bowel syndrome?quality of life (IBS-QOL), and gastrointestinal symptom rating scale (GSRS) scores were evaluated on the day of hospitalization, midway through the hospitalization period, and on the day of discharge. Abdominal pain was measured daily using NRS, and the score decreased from 8 at admission to 0 at discharge. The IBS-QOL percentile score improved from 42 points to 100 points. The total GSRS score also improved, from 30 points to 2 points. These results suggest that complex Korean medicine treatment with acupotomy, is useful for treating internal diseases, such as IBS, as well as musculoskeletal disorders.
The Effects of Treatment of Korean Medicine for Superior Labrum Anterior to Posterior Lesions: A Retrospective Chart Review
Authors: Park Ju-Hun , Cho Hyun-Woo , Park Han-Bin , Yoo Dong-Hwi , Kim Sang-Gyun , Kwon Oh-Hoon , Choi Kang-Eah , Choi Seong-Hun , Chu Hong-Min , Jang Jong-Won
Published: February 2020

Background: This study aimed to investigate the clinical effectiveness of treatment of Korean medicine on superior labrum anterior to posterior (SLAP) lesions.Methods: A total of 55 inpatients diagnosed with SLAP lesions by magnetic resonance imaging, were investigated from May 1st, 2014 to May 31st, 2019 at Haeundae Jaseng Hospital of Korean Medicine. The patients were sorted by gender, age, causing factor, illness duration, period of hospitalization, SLAP lesion type, complications, and treatments. Treatments included acupuncture, pharmacopuncture, Chuna therapy, herbal treatment, and physiotherapy. After treatment, the Numeric Rating Scale, Shoulder Pain and Disability Index, and European Quality of Life 5-Dimension questionnaire were used to evaluate treatment effect.Results: There were more males than females in this study (1:0.83). Patients were more likely to be in their 50s (38.18%), have an unknown etiology (70.91%), and be in the subacute disease stage (41.82%). According to the SLAP lesion type, most of the inpatients had Type 2 lesions (69.09%). For inpatients diagnosed with SLAP lesions, the mean shoulder numeric rating scale score decreased from 5.55 ± 0.90, to 4.07 ± 1.18 (p < 0.001), the mean Shoulder Pain and Disability Index score decreased from 50.35 ± 18.36, to 39.90 ± 19.34 (p < 0.001), and the mean European quality of life 5-dimension index increased from 0.70 ± 0.16, to 0.75 ± 0.13 (p < 0.01) after treatment.Conclusion: Treatment of Korean medicine effectively decreased pain and increased the quality of life of the patients with SLAP lesions in this study.
Research Trends in Pharmacopuncture Treatment for Lateral Epicondylitis
Authors: Yoo Jae Hee , Ko Hong Je , Jeong Sang Jun , Kim Min Wook , Kim Soo Hyun , Kim Seon Woo , Jang Seung Won , Shin Jeong Cheol
Published: February 2020

The aim of this study was to examine pharmacopuncture treatment for lateral epicondylitis, and to contribute to developing a standardized treatment regimen by reviewing trends in clinical trials. Five randomized controlled trials, 1 case-control study, and 8 cohort studies published after 1999, that involved pharmacopuncture for lateral epicondylitis, were selected from Korean and international online databases (n = 8). The type of pharmacopuncture, dose, frequency, efficacy, and adverse events were analyzed. Seven types of pharmacopuncture were used, namely Bee Venom, Illicium henryi Diels, Akebiae Caulis, Angelicae sinensis Diels, Ligusticum chuanxiong Hort, Hominis Placenta, and Salviae Miltiorrhizae Radix. Dose, treatment duration, and treatment frequency varied widely. One study assessed the treatment efficacy according to frequency. Nine studies lacked data on adverse events. The quality of 5 randomized controlled trials was low. Although pharmacopuncture treatment appeared to be effective for lateral epicondylitis, it was difficult to standardize the regimen for lateral epicondylitis.
Parenting and social solidarity in cross-cultural perspective
Authors: Faircloth Charlotte
Published: February 2020

Many scholars, particularly in Anglophone countries, have observed that mothers and fathers are now expected to do much more explicit ‘parenting’ than in the past. This article draws on the case studies of Norway and the UK as examples of welfare states with different historical orientations to social coherence, equality and diversity as a means of examining the spread (or otherwise) of these ideologies. In particular, it considers theoretical concerns of risk, responsibility and trust, especially as they relate to our ideas of childhood and adulthood. In short, the article suggests that an intensification of parenting has the potential to have a corrosive effect on notions of social solidarity, and makes the case instead for a societal conception of raising children.
How to spell the Greek alphabet letters.
Authors: Acerbi Fabio
Published: February 2020

A text contained in a 10th century manuscript and that provides a mathematical reason for spelling the Greek alphabet letters in a specific way is published and discussed.