bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the efficacy of bromfenac sodium in the treatment of dry eye disease
Authors:   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation, Loskutov I.A. , Semashko E.F. ,   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation, Khomyakova E.N. ,   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation, Makukha E.I. ,   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation, Kostina N.E. ,   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation
Published: March 2024

Background: to date, the efficacy of anti-inflammatory treatment in dry eye disease (DED) is still relevant. Aim: to evaluate the efficacy and safety of bromfenac sodium 0.09% ophthalmic solution plus artificial tears in patients with DED. Patients and Methods: 175 patients (350 eyes) with DED receiving artificial tears were enrolled. Subjective and objective assessment of symptom severity was performed and DED stage was determined before and 4 weeks after treatment with bromfenac sodium 0.09% ophthalmic solution based on the results of the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer's test and Norn's test. Adverse events were registered to assess the safety of bromfenac sodium 0.09%. Results: complex treatment of DED resulted in a 1.4-fold increase in Schirmer's test and Norn's test score and a significant improvement in typical symptoms based on the OSDI score. The average OSDI score decreased by 56% compared to baseline. The number of patients with moderate to severe DED decreased by 7% and 55% respectively. The number of patients with mild DED increased by 21%. After 4 weeks of treatment, 41% of patients were symptom free. All changes during the study were significant (p<0.05). No adverse events were reported with the use of bromfenac sodium 0.09%. Conclusion: bromfenac sodium 0.09% ophthalmic solution is clinically effective in DED. This medication increases total tear production, reduces the severity of symptoms and decreases the number of patients with severe and moderate disease, thereby improving the quality of life of these patients. KEYWORDS: bromfenac sodium, OSDI, dry eye disease, Schirmer's test, treatment efficacy. FOR CITATION: Loskutov I.A., Semashko E.F., Khomyakova E.N., Makukha E.I., Kostina N.E. Evaluation of the efficacy of bromfenac sodium in the treatment of dry eye disease. Russian Journal of Clinical Ophthalmology. 2024;24(1):7–13 (in Russ.). DOI: 10.32364/2311-7729-2024- 24-1-2.
Development of a new nanobiotechnology method for the differential diagnosis of ocular adnexal tumors
Authors:   Helmholtz National Medical Research Center, Moscow, Russian Federation, Saakyan S.V. , Skladnev D.A. ,   Federal Research Center "Fundamental Basis of Biotechnology", Moscow, Russian Federation, Alekseeva A.P. ,   Helmholtz National Medical Research Center, Moscow, Russian Federation, Beznos O.V. ,   Helmholtz National Medical Research Center, Moscow, Russian Federation, Sorokin V.V. ,   Federal Research Center "Fundamental Basis of Biotechnology", Moscow, Russian Federation
Published: March 2024

Aim: to develop a new nanobiotechnology method for the differential diagnosis of ocular adnexal tumors. Patients and Methods: 192 eyelid or conjunctival tumor samples from 192 patients were examined. Controls were healthy tissue samples from the same eye. To register and obtain significant differences in the generation of biogenic silver nanoparticles in situ, the key parameters of the reaction of the reduction of silver cations were selected and optimized. To generate de novo biogenic silver nanoparticles, tissue samples were placed in a sterile solution of a cation source in aseptic conditions. Nanoparticles were generated in situ using a sterile solution of Tollens' reagent (Ag(HN3)2NO3). Results: the optimal parameters of a new nanobiotechnology method were established to conduct the reduction reaction to generate biogenic silver nanoparticles. The required concentration of Tollens' reagent (source of cations) was 63 μg/ml. The wavelength used to observe the de novo generation of biogenic silver nanoparticles (λ) was 410 nm. Obtaining the most significant changes in the optical density of the reaction mixture with biogenic nanoparticles required 10 to 20 min, although the first changes were documented starting from the 5th minute of the reduction reaction. Benign and malignant tumors are characterized by different metabolic activities, i.e., benign eyelid and conjunctival tumors reduce cations more slowly than malignant tumors. The parameters of reducibility of benign ocular adnexal tumors did not significantly differ depending on tumor location and type. Among the malignant conjunctival tumors, melanoma is characterized by the highest reducibility p<0.05). Among the malignant eyelid tumors, no significant differences were found for different tumor types. Conclusions: this novel nanobiotechnology method provides a differential diagnosis of benign and malignant ocular adnexal tumors. The practical relevance of this method lies in differentiating benign and malignant tumors to schedule management strategies and surgical interventions. KEYWORDS: tumor, eyelids, conjunctiva, silver nanoparticles, biogenic synthesis, express diagnostics, ocular oncology. FOR CITATION: Saakyan S.V., Skladnev D.A., Alekseeva A.P., Beznos O.V., Sorokin V.V. Development of a new nanobiotechnology method for the differential diagnosis of ocular adnexal tumors. Russian Journal of Clinical Ophthalmology. 2024;24(1):25–29 (in Russ.). DOI: 10.32364/2311-7729-2024-24-1-5.
An Assessment of the Economic Viability of Delivering Solar PV Rooftop as a Service to Strengthen Business Investment in the Residential and Commercial Sectors
Authors: Leewiraphan Chavid , Ketjoy Nipon , Thanarak Prapita
Published: March 2024

The creation of significant power from PV technology has resulted from the growth of the solar PV business and industry and the lowering of PV costs. The electricity market is open broader for PV and other involved device technology. The goal of cumulative capacity drives Thailand's solar PV investment compass. The learning curve projection shows that the prediction's learning curve reliability can provide a clearer view for PV investment and policymakers. This paper shows the creation of the opportunity for the solar PV rooftop as a service (RaaS) business model, designed for four customers: residential and commercial, with small, medium, and large scales depending on their electricity consumption. The result reveals that if no grid is allowed, the medium- and large-scale are more likely to be feasible as they show grid parity. With the PV cost reduction trend, all the customers are economically viable in the grid sale allowed. Besides that, the electricity tariff rate from the grid also significantly impacts the PV rooftop investment and customer decision-making.
Are Trade Openness Drivers Relevant to Carbon Dioxide Emission? A Study of Emerging Economies
Authors: Suleman Shahida , Boukhris Mohamed , Kayani Umar Nawaz , Thaker Hassanudin Mohammad Thas , Cheong Calvin W. H. , Hadili Abduraawf , Tehseen Shehnaz
Published: March 2024

This research is focused on an in-depth analysis of the trade drivers that influence trade openness and their impact on carbon dioxide emissions, with a concentrated examination of emerging economies from 1995 to 2020. This examination is contextualized within the scope of various trade and environmental theoretical frameworks. In our analysis, we employed a range of advanced panel regression methods, including stepwise regression for model selection, as well as Fully Modified Ordinary Least Squares (FMOLS), Panel Ordinary Least Squares (Panel OLS), and Fixed Effects Model (FEM). The long-term patterns were evaluated using Johansen co-integration tests. Additionally, the study delves into the causal links between carbon dioxide emissions and the key drivers of trade, employing Granger causality tests for this purpose. Our findings disclose a complex web of relationships, both in the short and long term, between trade openness and carbon dioxide emissions, influenced by several key factors: (i) net inflows of foreign direct investment, (ii) trade reserves, (iii) per capita income, (iv) exchange rates, and (v) gross national savings.
Analisis Anggaran Biaya Produksi Sebagai Alat Pengendalian Biaya Pada Perusahaan Daearah Air Minum (PDAM) Kota Kupang
Authors: Reu Fransiskus Marlon
Published: March 2024

The problem raised in this research is how the procedure for preparing the production cost budget and the process of controlling production costs in PDAM Kupang Regency. The purpose of this study was to find out the procedure of preparing the production cost budget and for the process of controlling production costs at the kupang district drinking water company. The method used in this research is descriptive qualitative. The results showed that the calculation of production costs in PDAM Tirta Lontar Kupang Regency has not been in accordance with the theory and process of water production in PDAM Tirta Lontar Kupang Regency has always increased.
Analisis Faktor Quality Of Work Life (Qwl) yang Berhubungan Dengan Kepuasan Kerja Karyawan Bagian Rekam Medis di Rumah Sakit Panti Rapih Yogyakarta
Authors: Dima Rohani Purnamasari
Published: March 2024

Penelitian ini dilakukan untuk mengetahui hubungan faktor-faktor Quality of Work Life dengan kepuasan kerja karyawan bagian Rekam Medis di Rumah Sakit Panti Rapih Yogyakarta.  Ada hubungan antara faktor-faktor Quality of Work Life dengan kepuasan kerja karyawan bagian Rekam Medis di Rumah Sakit Panti Rapih Yogyakarta, dengan hasil 0,001 < 0,05 pada faktor keterlibatan karyawan dan 0,000 < 0,05 pada faktor kompensasi yang seimbang, rasa aman terhadap pekerjaan, keselamatan lingkungan kerja, rasa bangga terhadap institusi, pengembangan karier, fasilitas yang tersedia, penyelesaian masalah, dan komunikasi, dan hubungan yang kuat terdapat pada faktor kompensasi yang seimbang. Hasil dari analisis dan pembahasan menunjukkan bahwa ada hubungan yang sedang antara delapan faktor (keterlibatan karyawan, rasa aman terhadap pekerjaan, keselamatan lingkungan kerja, rasa bangga terhadap institusi, pengembangan karier, fasilitas yang tersedia, penyelesaian masalah, dan komunikasi) sedangkan hubungan yang kuat terdapat pada faktor kompensasi yang seimbang, faktor-faktor Quality of Work Life juga memiliki hubungan yang signifikan dengan kepuasan kerja.
Analisis Penerapan Bauran Pemasaran 7P di Hotel Ima Kupang
Authors: Kabanga Margaretha Sartien
Published: March 2024

Gaya hidup konsumen yang berbeda dan persaingan yang ketat membuat hotel Ima harus memiliki strategi pemasaran yang tepat agar hotel dapat mencapai target yang diinginkan. Dalam mendekripsikan analis bauran pemasaran yang tepat pada Hotel Ima digunakan marketing mix 7p. Teknik pengumpulan data yang digunakan yaitu dengan menggunakan wawancara. Wawancara dilakukan kepada CEO, manajer pemasaran, general manajer. Hasil penelitian menunjukkan bahwa pada product, produk utama Hotel Ima adalah kamar dengan berbagai tipe dan fasilitas. Untuk price, dalam penetapan harga Hotel Ima mengacu pada fasilitas, standart bintang, serta melihat kompetitor. Untuk Promotion, terdapat dua strategi diterapkan dalam Hotel Ima yaitu pull dan push strategi. Untuk Place, letak Hotel Ima strategis. Untuk People, karyawan melakukan pelayanan yang baik, cepat, ramah, teliti dan akurat. Pada Process, dalam proses jasa Hotel Ima diawali dengan peran marketing & sales dan segala proses hasil pemasaran dilaporkan oleh manajer pemasaran. Terakhir Physical Evidence, Hotel ima memiliki bangunan yang kokoh dan klasik.
Pengaruh Struktur Modal Dan Kinerja Keuangan terhadap Profitabilitas
Authors: Angela Jovita
Published: March 2024

Penelitian ini bertujuan untuk mengukur pengaruh struktur modal dan kinerja keuangan perusahaan terhadap profitabilitas Perusahaan Grup Lippo yang terdaftar di Bursa Efek Indonesia periode 2008 – 2018. Teknik pengambilan sampel adalah nonprobability sampling, lebih tepatnya purposive sampling. Populasi penelitian ini adalah Perusahaan Grup Lippo yang terdaftar di Bursa Efek Indonesia yang terdiri dari 12 perusahaan, dan sampelnya adalah laporan keuangan 10 tahun terakhir dari 3 Perusahaan Grup Lippo untuk mewakili 12 perusahaan tersebut. Teknik analisis data adalah analisis regresi linier berganda dan menggunakan aplikasi SPSS versi 16,0. Hasil penelitian menunjukkan bahwa struktur modal berpengaruh secara parsial terhadap profitabilitas, terlihat dari nilai signifikansi sig 0,042 < 0,05 atau nilai t hitung > nilai t tabel (2,396 > 2,052). Kinerja keuangan juga berpengaruh secara parsial terhadap profitabilitas yang terlihat dari nilai signifikansi sig 0,000 < 0,05 atau nilai t hitung (4,181) > nilai t tabel (2,052). Struktur modal dan kinerja keuangan secara simultan berpengaruh positif terhadap profitabilitas yang terlihat dari nilai signifikansi sig 0,000<0,05 atau nilai Fhitung (11,332) > nilai Ftabel (3,34).
Pengaruh Kualitas Produk terhadap Kepuasan Konsumen pada Meubel Sumber Kasih Sikumana Kota Kupang
Authors: Tantriadisti Shinta , Ulfah Maria , Kertayoga I Putu Ajie Windu , Renoat Ronald
Published: March 2024

Penelitian ini bertujuan untuk mengetahui pengaruh kualitas produk terhadap kepuasan konsumen pada meubel sumber kasih sikumanadi Kota Kupang. Penelitian ini menggunakan metode kuantitatif dengan teknik pengumpulan data penelitian adalah wawancara tertulis. Alat pengumpulan data adalah angket. Teknik analisis data menggunakan analisis linear sederhana. Variabel dalam penelitian ini adalah variabel bebas (X kualitas produk dan variabel terikat (Y) adalah kepuasan konsumen. Penelitian ini dilaksanakan di Sikumana Kota Kupang pada Meubel Sumber Kasih Bulan September sampai bulan November 2020. Populasi dari penelitian ini adalah konsumen meubel sumber kasih .Sampel yang ditetapkan sebanyak 30 orang (Accidental Sampling) yang sudah pernah membeli produk pada Meubel Sumber Kasih .Teknik yang digunakan adalah teknik Accidenial Random sampling, yang merupakan pemilihan sampel oleh peneliti yang kebetulan ditemui pada saat pengambilan data.Instrumen yang digunakan valid dan reliabel, sedangkan uji prasyarat analisis menunjukkan adanya pengaruh antara Kualitas Produk kepuasan konsumen yang dibuktikan dengan analisis regresi linier berganda dan uji F pada datanya. Teknik Analisis data menggunakan analisis anova satu jalur.Hasil penelitian mwnggunakan regresi linear sederhana menunjukan bahwa Nilai thitung = 4,180 dikonsultasikan dengan ttabel = 2,048 pada taraf signifikansi 5%. .Hasil perhitungan statistik menunjukan nilai Fhitung sebesar 17,472 dengan nilai signifikan sebesar 0,000 < 0,05. Sedangkan pada taraf signifikan 5% dan db= N-2 = 30-2 = 28 maka diperoleh Ftabel sebesar 3,34 sehingga nilai Fhitungsebesar 17,472> nilai Ftabel sebesar 3,34.Hasil pengujian menggunakan uji F diketahui thitung ≥ ttabel maka hipotesis alternatif (Ha) diterima dan Hipotesis Nihil (Ho) ditolak dan diinterpretasikan bahwa ada pengaruh kualitas produk terhadap kepuasan konsumen. Maka dalam hal ini kualitas produk yang semakin baik memberi pengaruh terhadap kepuasan konsumen dan semakin meningkatkan jumlah produk meubel yang terjual.
Efektif Mikroorganizma ve Karahindiba Ekstraktının Buzağılarda Performans Üzerine Etkisi
Authors: Özbek Veli , Kocaoğlu Güçlü Berrin , Büyükkılıç Beyzi Selma , Küçükoflaz Mehmet
Published: March 2024

Bu çalışmada, buzağılarda efektif mikroorganizma (EM) ve karahindiba ekstraktının (KH) performans [canlı ağırlık (CA), canlı ağırlık artışı (CAA), yemden yararlanma oranı (YYO), vücut ölçüleri], rumen uçucu yağ asitleri (UYA) üzerin-deki etkilerinin belirlenmesi amaçlanmıştır. Çalışmada toplam 80 buzağı, ırkları (10 Holstayn, 10 Simental), yaşları (7±3 günlük), canlı ağırlıkları (40±5 kg), ve cinsiyetleri (10 erkek, 10 dişi) benzer olacak şekilde bir kontrol ve üç deneme grubu (EM, KH ve EM + KH) olmak üzere her grupta 20 buzağı olacak şekilde toplam dört gruba ayrıldı. Çalışmada yer alan bütün buzağıların beslenme programları aynı olup, deneme grubunda bulunan buzağılara kontrol grubundan farklı olarak, EM grubunda buzağı başına günlük 10 ml EM ve KH grubunda 5 gr karahindiba ekstresi ve EM + KH grubunda ise 10 ml EM ile 5 gr KH süte katılarak oral yolla içirildi. Simental ırkı buzağılara KH, EM veya KH+EM verilmesinin performans parametreleri (CA, CAA, YT, YY), vücut ölçüleri ve rumen UYA (asetik asit, butirik asit, propiyoinik asit) oranını önemli oranda etkilemediği belirlendi. Öte yandan Holstein ırkı buzağılara KH verilmesinin yem tüketimini önemli oranda artırdığı belirlendi. Holstein ırkı buzağılara sütten kesim öncesi dönemde KH verilmesinin yemden yarar-lanma oranını etkilemediği ancak EM veya KH+EM verilmesinin yemden yararlanma oranını olumsuz etkilediği belirlen-di. Holstein ırkı buzağılara sütten kesim öncesi dönemde KH verilmesinin sağrı genişliği ve günlük sağrı genişliği artışı-nı düşürdüğü ancak muamelelerin deneme sonu rumen UYA düzeyleri, cidago yüksekliği, sağrı yüksekliği, vücut uzun-luğu, beden derinliği ve göğüs çevresi ile günlük cidago yüksekliği artışı, sağrı yüksekliği artışı, vücut uzunlu artışı, beden derinliği artışı ve göğüs çevresi artışını etkilemediği kaydedildi. Sonuç olarak, ruminantlarda gerek bitki ekstrak-ları gerek probiyotiklerin ve prebiyotiklerin yem katkısı olarak kullanıldığı çalışma sayısı bu katkıların etkileri konusunda kesin kanaat oluşturmak için oldukça yetersiz olup ruminantlarda çok daha fazla çalışma yapılmasının gerekli olduğu düşünülmektedir.
Effect Of The Quality Of Mulberry Leaves Morus alba Against The Silkworm Nutrition Index Bombyx mori L. (Lepidoptera:Bombicidae)
Authors: Tanjung Masitta
Published: March 2024

Th leaf quality effect of mulberry (Morus alba) on nutrition index of silkworm (Bombyx mori L.) has been studied. This research was design according to Completely Randomized Design (CRD) with 2 treatments which are an unfertilized mulberry plant, and the fertilized mulberry plants with urea, triple super phosphate (TSP), nitrogen, phosphor, and potassium (NPP). Twenty times replications was applied for each treatment. The results showed that the leaf of fertilized mulberry plant is evidently increased the growth and the consumption rate on the conversion efficiency of instar III, the feed digestion of instar V, the efficiency of food conversion of instar IV and V, and the estimate of feed digested of instar IV with the number for each was 36% and 26%, 30%, 34% and 67%, 24%, respectively.Bombyx mori L.
Diversity of Insect Pests in Plants of Coffee (Coffea arabica L.) in Sigumpar, Humbang Hasundutan, North Sumatera
Authors: Bio Nursal
Published: March 2024

Both methods were carried out in 5 locations based on the age of coffee, 3, 5, 10, 15, and 20 years. The area of the Searching and Direct Observation and Hand Picking method is 20x20 meters which was carried out diagonally. Data collected included the number of species and individuals, density (K), relative density (KR),attendance frequency (FK), diversity index (H '), equitability index (E) and its similarity index (IS). The results of the observation showed that 4 pest orders, 8 families, 10 species and 225 individuals were obtained. During the day 9 species of insects were found with 4 orders, 7 families, and 198 individuals and at night there were 4 types of insects with 2 orders, 3 families and 31individuals. Hypothenemus hampeii is the species with the highest K, KR and FK values of all locations with each value of 0.045 ind / m2, 41.86% and 100%. The highest Diversity Index (H ') value is found at location 5 (1,841) and the lowest value at location 1 (1,178). The highest Equitability value (E) is found in location 1 (0.849) and the lowest value at location 5 (0.799). The highest Similarity Index (IS) is found in locations 4 and 5 with a value of 94.73% and the lowest at locations 1 and 5 with a value of 57.14%.
Ecology Of Pranajiwa Medicinal Plants (Euchresta horsfieldii (lesch.) benn.) In Bali And Lombok: (A Review)
Authors: Rafika Rizki
Published: March 2024

This article is a review of the ecology of pranajiwa medicinal plants in Bali and Lombok. In this article, the author discusses the characteristics of pranajiwa's original habitat in Bali and Lombok, the abundance, habitat vegetation, and distribution of pranajiwa, as well as environmental factors that affect pranajiwa's habitat. The purpose of this article is to identify the characteristics of pranajiwa's natural habitat in Bali and Lombok to ensure long-term preservation and sustainable use of pranajiwa
Plasma Sirt-1 Level in Various Frailty Degree in Elderly Outpatients at Prof. Chairudin P. Lubis Hospital, Medan
Authors: Fadhilah Hayati  , Dedi Ardinata  , Nuraiza Meutia  , Ririe Fachrina Malisie  , Muhammad Ichwan
Published: March 2024

Frailty is a physical aging syndrome characterized by health vulnerability. Diagnosis is established incorrectly based on three or more of the five criteria: weakness, decreased walking speed, fatigue, decreased physical activity, and weight loss. Sirtuin 1 plays a role in weakness, particularly in the elderly, acting as a protective factor during weakness, and its activation could provide a novel therapeutic approach. However, research in this area is still very limited. A cross-sectional method with observation or measurement of study subjects was employed in this research, involving a total of 118 elderly subjects selected through non-probability sampling. Pearson correlation test indicates a relationship between the polymorphism genotype (rs2273773) in the SIRT1 gene and the frailty scale (p-value < 0.05), while no relationship was found between plasma SIRT1 levels and the frailty scale (p-value > 0.05). Furthermore, the F-test reveals a significant simultaneous relationship between the polymorphism genotype (rs2273773) and plasma SIRT1 levels with frailty (p-value < 0.05).
A REVIEW IN GENOMIC AND PRECISION MEDICINE ON CANCER IN INDONESIA
Authors: Widjaja Sry suryani , Rusdiana  , Yudhistira Ashri
Published: March 2024

Genomic and precision medicine has been a new target on oncology field, as with the genomic study, we can develop the precised medicine. This studies was made to find the development of research on genomic and precision medicine on cancer in Indonesia. This study is conducted systematically to explore an update on genomic and precision medicine on cancer in Indonesia based on the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) to extend this scoping review. After further research and exploration, we found 7 literatures that shares the same inclusion criteria. From these seven literatures, we found that there is a significant development in this field of research, however most studies are about the detection of gene and has not develop research in treament or rehabilitation. Indonesia is a capable country to develop this field of research. With that being said, the encouragement and empowerment of researchs in Indonesia on genomic and precision medicine must be enchanced.
EFEKTIVITAS PENERAPAN ONLINE SINGLE SUBLISSION (OSS) PADA DPMPTSP KOTA LUBUKLINGGAU DENGAN MENGGUNAKAN FRAMEWORK ITIL. V3.
Authors: Firliansa Nizar , Cholil Widya
Published: March 2024

Semakin majunya perkembangan zaman yang sarat dengan pemanfaatan teknologi informasi seharusnya dapat menjadi solusi dalam masalah pelayanan publik yang ada. Teknologi informasi dapat dimanfaatkan untuk meningkatkan pelayanan menjadi lebih cepat, transparan sehingga pelayanan publik menjadi lebih efektif dan efisien. Pelayanan publik berbasis teknologi informasi perlu diterapkan untuk mengurangi resiko terjadinya diskriminasi dalam memberikan pelayanan, ketidakpastiaan mengenai waktu ataupun biaya pelayanan dan tentunya mengurangi pungutan liar yang sering terjadi. Paper ini menjelaskan analisa bagaimana efektivitas penggunaan Sistem Online Single Submission (OSS) dalam penerbitan izin pada Dinas Penanaman Modal dan Pelayanan Terpadu Satu Pintu kota Lubuklinggau dengan menggunakan framework Information Technology Infrastructure Library (ITIL) Versi 3. Online Single Sebmission (OSS) merupakan aplikasi yang digunakan untuk segala proses registrasi dan pengajuan perizinan usaha serta pengajuan perijinan lainnya yang termasuk di dalam layanan perijinan berusaha menurut Peraturan Pemerintah Nomor 24 Tahun 2018 Tentang Pelayanan Perizinan Berusaha Terintegrasi Secara Elektronik dengan alamat https://oss.go.id. Hasil dari paper ini diharapkan dapat bermanfaat bagi pemerintah Kota Lubuklinggau untuk terus memperbaiki kualitas pelayanan publik kepada masyarakat dan dengan harapan pemerintah dapat meningkatkan pelayanan publiknya kearah yang lebih baik di masa mendatang.

 

Kata    kunci: Online Single Submission (OSS), E-Government, Information Technology Infrastructure Library (ITIL).
БЕЗПЕКОВІ АСПЕКТИ ЗАСТОСУВАННЯ РИЗИК-ОРІЄНТОВАНОГО УПРАВЛІННЯ ПІДПРИЄМСТВОМ В УМОВАХ ВОЄННОГО СТАНУ
Authors: Штангрет Андрій , Караїм Мирослава , Караїм Остап
Published: March 2024

В межах останні кількох років діяльність українських підприємств перебуває під впливом значної кількості факторів, ключовими з яких стали COVID-19 та військові дії. Ключовим є не лише сам факт виникнення та суттєвості впливу зазначених факторів, але те, що ситуація у середовищі функціонування характеризується максимальною динамікою, а відтак високою невизначеністю, коли раніше накопичений досвід не забезпечує необхідної початкової інформаційної основи для прийняття управлінських рішень. Значна частина менеджерів фактично пасивні до будь-яких ініціатив, зокрема таких, що передбачають в тактичному плані покращення конкурентних позицій. Зазначена актуалізує необхідність широкого застосування ризик-орієнтованого управління на основі врахування фактичних засад здійснення безпекової діяльності в умовах певного підприємства. Обґрунтовано, що активність суб’єктів безпеки повинна бути спрямована на підштовхування до ініціативності менеджменту, інформаційний супровід та загальний контроль за розробленням й реалізацією рішення для збереження цілісності підприємства попри вищий рівень ризику. Аргументовано доведено важливість розвитку ризик-орієнтованого мислення як за рахунок покращення професійних компетенцій, так й змін в корпоративній культурі.
ЗАБЕЗПЕЧЕННЯ ЕКОНОМІЧНОЇ БЕЗПЕКИ ПІДПРИЄМСТВ ЕЛЕКТРОННОЇ ТОРГІВЛІ В УМОВАХ ВПЛИВУ СУЧАСНИХ ЗАГРОЗ
Authors: Яремик Мирослав , Черненко Андрій
Published: March 2024

Метою дослідження є характеристика особливостей забезпечення економічної безпеки підприємств електронної торгівлі в умовах сучасних загроз. Доведено, що електронна комерція стала невід'ємним компонентом глобальної торгівлі та комерції, представляючи значну частину економічної діяльності у всьому світі. Виокремлено сучасні загрози в системі забезпечення економічної безпеки підприємства електронної торгівлі. Визначено, що система управління економічною безпекою повинна використовувати цілісний підхід, який включає не лише технологічні гарантії, а й організаційну стійкість та співпрацю зацікавлених сторін. Охарактеризовано дії суб’єктів економічної безпеки в контексті протидії основним загрозам. Встановлено, що ігнорування негативного впливу сучасних загроз на економічну безпеку підприємств електронної торгівлі може мати тяжкі наслідки, які загрожують їх діяльності, репутації та довгостроковій життєздатності.
КРИТЕРІЇ ТА ПОКАЗНИКИ ГОТОВНОСТІ ЛОГОПЕДІВ ДО РОБОТИ З ГЕТЕРОГЕННИМИ ГРУПАМИ ДІТЕЙ
Authors: Турубарова Анастасія Володимирівна , Клочкова Юлія Володимирівна , Король Альона Валеріївна
Published: March 2024

Стаття є докладним дослідженням готовності логопедів до роботи з гетерогенними групами учнів в умовах інклюзивної освіти. Автори ретельно проаналізували ряд факторів, які визначають ефективність педагогічної взаємодії в цьому контексті. Зокрема, в статті розглядається визначення понять «гетерогенність» та «гетерогенна група у школі», що становлять важливу основу для подальшого розгортання дослідження. Окремо виділяється структура готовності логопеда до роботи з гетерогенними групами, яка включає в себе вісім ключових компонентів. Це теоретична підготовка, педагогічні методи та прийоми, мовленнєвий аспект, психологічна готовність, комунікаційні навички, технології та інновації, співпраця з іншими фахівцями, і особистісний розвиток. Кожен з цих компонентів визначає важливі аспекти готовності логопеда до роботи в інклюзивному середовищі. Дослідження виокремлює три рівні готовності логопедів до педагогічної взаємодії з гетерогенними групами учнів – низький, середній та високий. Для оцінки цих рівнів використовуються чотири критерії: мотиваційний, інформаційно-пізнавальний, особистісний та аналітичний. Такий підхід дозволяє детально визначити ступінь готовності кожного логопеда до роботи в гетерогенних групах та розкрити особливості їхньої професійної компетентності. Окремий аспект дослідження стосується зовнішніх і внутрішніх чинників, що впливають на готовність логопедів. Зовнішні чинники включають реформування системи освіти, які створюють передумови для інклюзивної парадигми та підсилюють суспільний попит на фахівців, здатних ефективно працювати в умовах інклюзії. Внутрішні чинники стосуються професійно-особистісних якостей майбутнього педагога, таких як толерантність, емпатія, стресостійкість, емоційна мобільність, рефлексивність, педагогічна майстерність, творчість та інші. Ці якості визначають успішну роботу логопеда в гетерогенному середовищі.
Live Location Sharing System (L2S2): Empowering Management of Unmanned Aircraft Systems (UAS) Operations
Authors: Mohamad Sharom Muhammad Akmal Asraf , Ahmad Fauzi Mohd Fazuwan , Sipit Abd Razak
Published: March 2024

Transparency and confidence-building measures in Unmanned Aircraft Systems (UAS) operations continue to be important topics of discussion in various contexts. Transparency helps build trust and alleviate concerns about the use of UAS, especially in sensitive areas or situations where privacy and security are paramount. Meanwhile, confidence-building measures aim to establish trust and mitigate potential risks associated with UAS operations, particularly in complex UAS operations involving multiple teams. These measures include implementing systems that enable the identification and tracking of UAS operations activities that can be achieved through technologies such as global positioning system (GPS)-based tracking systems. Although there are several UAS operations GPS-based management systems available in the market, it requires a certain initial investment cost that creates a barrier for some parties, particularly smaller organisations or those with limited budgets. Therefore, in this study, we have developed a web-based application called as Live Location Sharing System (L2S2) by leveraging the capabilities of Traccar, a free and open-source GPS tracking system. Through this system, the movement activities of the Malaysian Space Agency (MYSA) UAS operation teams can be monitored in real-time by the mission commander, which has finally empowered the management of UAS operations as a whole.
Quality of Life of Patients with Diabetes Mellitus Based on Their Characteristics
Authors: Joeliantina Anita , Antasyia Nur Lailia , Hamid Irfany Nurul , Purnamawati Dewi
Published: March 2024

The quality of life of patients with diabetes mellitus (DM) describes the degree of health and limitations that need to be evaluated to administer treatment. The purpose of this study was to identify quality of life based on patient characteristics. This research is descriptive with a cross-sectional approach. The sample size used was 87 adult patients with DM determined through purposive sampling techniques. This research was carried out from December 2021 to January 2022 at the Bangkingan Surabaya Health Center. Data was collected using questionnaires and analyzed using descriptive analysis. The results of this study showed that patients with DM who had a high quality of life were 50.6% and 49.4% showed a low quality of life. Based on the identification of patient characteristics data that describe the high quality of life are early elderly patients with an age range of 46-55 years (25.3%), female (39.1%), high school education (18.4%), and not working (33.5%). Other data obtained were patients with no family history (31.1%), duration of DM 1-5 years (26.5 and the majority using a single antidiabetic drug. Based on these data, patients still need to get continuous education to manage diabetes. blood glucose levels and can improve quality of life. The characteristics of DM sufferers can be an alarm that makes sufferers aware of the changes that occur in them. Patients who can recognize the characteristics in themselves will be able to maintain their quality of life.
Introducción a la teoría de la argumentación
Authors:   Universidad de Guadalajara, Leal Carretero Fernando , Ramírez González Carlos , Favila Vega Víctor Manuel
Published: March 2024

Argumentar es la operación mental y comunicativa que más se necesita en todas las ocupaciones y profesiones. Queremos que nuestros profesionales argumenten mucho y bien. Esta obra representa un esfuerzo del cuerpo académico “Retórica, lógica y teoría de la argumentación” de la Universidad de Guadalajara con el propósito de brindar a la comunidad universitaria herramientas para mejorar sus prácticas argumentativas. En sus páginas el lector encontrará una selección de textos escritos por expertos en el tema dirigida a estudiantes de preparatoria y universidad, así como docentes y público en general interesados en fortalecer la claridad y solidez de los argumentos en sus discursos escritos que elaboran y analizan.
Cumbia somos
Authors:   Universidad de Guadalajara, Blanc Enrique , Inzillo Humphrey
Published: March 2024

De la movida sonidera mexicana a la cumbia villera argentina, de la psicodélica chicha peruana al sonido ancestral colombiano, la cumbia es un bien cultural que une e identifica a Latinoamérica. Este libro, producto del trabajo colaborativo con la Red de Periodistas Musicales de Iberoamérica, propone un repaso por las historias de músicos y bandas icónicas, desde los inicios de este género musical hasta las vanguardias más recientes. Cumbia somos recupera las peculiaridades geográficas y sociales que inciden en cada una de las aproximaciones y apropiaciones de ese lenguaje tropical expansivo y honra la multiplicidad de sonidos emanados del género: de artistas, como Totó La Mamposina, Los Ángeles Azules, Los Mirlos, Los Palmeras, Celso Piña, Yeison Landero, Gilda o Polibio Mayorga, de sellos emblemáticos, como Discos Fuentes, Codiscos y de colectivos, como Zizek, Los Pirañas y Sonido Gallo Negro. La cumbia es una banda sonora transgeneracional y multicultural, un patrimonio musical y bailable de la humanidad. ¡Que viva la cumbia y se baile por siempre!
Fotolibro para generar conciencia sobre el tráfico ilícito de las orquídeas a través del conocimiento del circuito comercial formal
Authors: Pérez Chong María Fernanda , Yarlequé Carlos
Published: March 2024

Este proyecto se origina a raíz de una problemática relacionada con la venta ilícita de orquídeas. Busca reflejar este escenario desfavorable para el mercado de la orquídea en la ciudad de Moyobamba, eje de producción y comercio de la especie. Para ello, se evidencia el contexto que rodea a la orquídea didáctica y dinámicamente a través de un fotolibro, con la intención de lograr la concientización del consumidor de la planta. Asimismo, se emplea un análisis cuantitativo y cualitativo a través de encuestas y entrevistas a profundidad, donde se toma una muestra de 153 personas para evaluar los resultados del proyecto. Finalmente, a partir de los resultados obtenidos tras la presentación del libro y la evaluación de los resultados, se demuestra que la mayoría de las personas participantes no conocían a profundidad el circuito de desarrollo de las orquídeas, así como tampoco el mercado legal e ilegal que las rodea. En este sentido, el libro cumple con su objetivo principal: concientizar e informar acerca del mercado de las orquídeas en el Perú y sobre todo en Moyobamba, centro neurálgico de desarrollo de la orquídea en el país.
Inka Khipus, Thread Wrappings and Subject Markers
Authors: Milillo Lucrezia
Published: March 2024

This work aims to contribute to our current understanding of how information was organized in khipus, Andean colourful knotted cords used as writing. If the idea that khipu signs could work as a flow chart was common in the last two decades, it is not until the notion of kayte as subject marker was elaborated by Sabine Hyland on the basis of Julio C. Tello's notes that the theory could be discussed on more empirical grounds. So far, the term “kayte” applied to needlework bundles, pompons or tufts attached to the beginning of the primary cord. In this work, the notion will be expanded to thread wrapped segments on Inka-style khipus. To this point, the discussion on the presence of thread wrappings on khipus has been predominantly relegated to Wari khipus, khipus understood to be outside the Inka standard, or post-Inka idiosyncratic “canuto” khipus. Here, thread wrapping present on the primary cord of Inka style khipus will be discussed as a possible specific type of kayte – or subject marker. Consulting literature on Andean thread wrapping technology, thread wrapped kaytes are proposed to be indicators of content related to personhood or territory.

Este trabajo pretende contribuir a nuestra comprensión actual de cómo se organizaba la información en los quipus, una tecnología andina de cuerdas coloradas y anudadas utilizada como escritura. Si la idea de que los signos en el quipu podrían funcionar como un diagrama de flujo era común en las últimas dos décadas, no es hasta que Sabine Hyland, a partir de las notas de Julio C. Tello, elaborò la nocion de "kayte" como marcador de sujeto de que la teoría podía discutirse sobre bases más empíricas. Hasta aquel momento, la palabra “kayte” se aplicaba a mechones de costura, o pompones atados al inicio del cordón primario. En este trabajo, la noción de kayte o marcador semántico se ampliará para incluir cuerdas envueltas en quipus de estilo Inca. Hasta este punto, la discusión sobre la presencia de cuerdas envueltas en los khipus se ha relegado predominantemente a los quipus Huari, quipus entendidos como fuera del estándar Inca, o quipus idiosincráticos “canuto” post-Incaicos . Aquí se considerarán las cuerdas envueltas presente en el cordón principal de los quipus de estilo Inca como un posible tipo específico de kayte o marcador de sujeto. En comparación con la literatura sobre la tecnología andina de cuerdas envueltas, se propone que los kaytes de cuerdas envueltas sean indicadores de contenido relacionado con la personalidad o el territorio.
Festones en pequeñas vestimentas de enterratorios de altura (Capacocha)
Authors: Cereceda Bianchi Verónica
Published: March 2024

Los festones son bordados exteriores que se incorporan en prendas ya terminadas en un telar. En el presente texto intentamos un análisis de este tipo de terminaciones que circundaba las vestimentas de pequeñas estatuitas en esos importantes rituales de sacrificios infantiles que son las capacocha. Por la cantidad de reglas que implicaba su elaboración, tanto en lo que se refiere a su ubicación como en la sintaxis de su organización cromática, es posible considerarlos como verdaderos códigos que cumplían sus mensajes de comunicación y sus posibles poderes rituales, a partir de angostas listas de diferentes colores, sin necesidad de utilizar palabras.

The festoons are external embroideries that are incorporated in garments already finished in a loom. In the present text we attempt an analysis of this type of completions that surrounded the garments of miniature figurines in those important rituals of children sacrifices named as capacocha. Due to the number of rules involved in their elaboration, both in terms of their location and the syntax of their chromatic organization, it is possible to consider them as true codes that fulfilled their communication messages and their possible ritual powers, based on narrow lists of different colors, without the need to use words.
Instabilities of the Image
Authors: Aziz Andrew
Published: March 2024

Architects have relied on image-making technologies and techniques, both analog and digital, to speculate on and document architecture. However, since Ivan Sutherland created Sketchpad - a Computer-Aided Design (CAD) software - in the mid-1960s, computation in architecture has largely been situated in the realm of workflow optimization, replicating analog image-making processes digitally to make them more efficient. This thesis proposes instead to use the digital image as a point of departure, affording an opportunity to explore architecture from a perspective outside of analog image-making. In the spirit of Peter Eisenman’s explorations of architecture’s interiority, this work uses the digital image as both a methodology and a foil in the context of architecture’s analog, lineament-based, image-making history. This attempts to expand on architecture’s disciplinary boundaries by using the discrete, statistical substructure of the digital image as the protagonist to study architectural constructs which have emerged and settled in an analog paradigm.
Productive Discomfort: Canadian Hooked Rugs and the Pedagogy of Unwelcome Mats
Authors: Cullen Lauren
Published: March 2024

If the function of a welcome mat is to greet guests with niceties, what can an unwelcome mat offer? Common greetings like “welcome” and “home sweet home” can be found on the hooked rug objects placed on opposite sides of a doorway. However, anti-racist, anti-colonial and feminist queer crip perspectives remind us that objects and spaces are never truly welcoming to all. Spaces are not neutral and objects are not as benign as they may seem. Hooked rugs are commonly understood as a Canadian folk art medium, a cultural product and a process of making that emerged with the settlement of British colonisers and European immigrants beginning in the 18th century in Maine and Nova Scotia. This dissertation establishes how the material culture of rug hooking pedagogically contributes towards settler colonial logic and narratives. In addition to exploring how rug hooking maintains settler colonial values and myths, I examine how arts-based research methods and specifically research-creation uniquely respond to and interrogate the colonial conventions found in rug hooking cultures. Through the development and facilitation of a rug hooking exhibition featuring seven “unwelcome” rugs, this dissertation considers the potential of textile-based craft in drawing attention to how settler societies operate, and what confrontation and discomfort look like within the feminised and informal space of craft. I posit the practice of socially based craft within a larger conversation of research-creation in the social sciences and humanities, and contribute to the theorization of artistic ways of knowing. The project also includes a zine intended to be circulated amongst rug hooking communities and shares critical reflections about Canadian rug hooking. Through the research process two key findings emerged: providing resources and paying people to learn craft is critical, and additionally the social space of craft is a place for critical learning informed by collaboration and co-making.Acentral argument this dissertation posits is that the culture and social practice of rug hooking can reflect and circulate myths and doctrines related to the settlement of Canada and simultaneously operates as a site of resistance against colonial power and logic.
Unified Approach for Liveload Moments and Deflections in Orthotropic Bridge Deck Due to CHBDC Truckloading
Authors: Hamed Ahmed
Published: March 2024

The current Canadian Highway Bridge Design Code includes design provisions to establish live load moment demands for reinforced concrete decks over longitudinal girders, orthotropic deck over longitudinal girders, and orthotropic deck over transverse beams. However, it only provides an equation for the factored applied moment on the deck as a function of the girder spacing, neglecting the effect of flexural and torsional rigidities of the deck. As a result, a parametric study was carried out in order to produce new empirical expressions for moment in bridge decks subjectedto truck wheel loading, takinginto account each of the three cases oforthotropy, namely: relatively torsionally stiff, flexurally soft decks, relatively uniformly thickness decks, and relatively torsionally soft, flexurally stiff decks. Bridge deck design can be treated in a unified manner across different deck types using the proposed formulations, accounting for longitudinal and transverse flexural rigidity of decks. The use of these methods can significantly simplify deck analysis and allow bridge engineers to compare different deck design alternatives.
AVIATION BUSINESSES DURING COVID-19: AIRASIA'S FINANCIAL CHALLENGES AND POSSIBLE WAY-OUTS
Authors: Ramli Nur Ainna , Ramli Nurshamimitul Ezza , Zulkifli Siti Fateha , Wahab Siti Nur Aqilah Ab
Published: March 2024

Purpose: This paper aims to discuss the financial challenges faced by AirAsia and the possible way-outs in the wake of the company’s slumped performance caused by COVID-19.
Design/methodology/approach: The methods used are qualitative, in-depth company studies and articles.
Findings: The result of this study can be concluded that AirAsia has several financial challenges that the analysis can see of the company’s finances. AirAsia also strives to implement several strategies to cope with COVID-19’s impact despite enormous and competing challenges and uncharted solutions.
Research implications: This article provides an overview of the strategy implemented by AirAsia after experiencing a downturn due to the COVID-19 pandemic.
Necesidad de tipificación de la violencia vicaria en el Código Orgánico Integral Penal ecuatoriano
Authors: Argudo Tello Adriana Maritza , Gómez de la Torre Jarrín Gina Lucía
Published: March 2024

Introducción: La violencia vicaria es una forma de violencia de género que afecta a mujeres y niños en todo el mundo, incluyendo Ecuador. A pesar de su gravedad, esta forma de violencia no siempre es reconocida o tipificada en la legislación penal ecuatoriana. Objetivo: Este estudio tiene como objetivo principal analizar la necesidad de tipificar la violencia vicaria en el Código Orgánico Integral Penal ecuatoriano, con el fin de brindar protección legal a las víctimas de este tipo de violencia. Metodología: Se emplearon métodos de análisis documental, revisión bibliográfica, estudio de casos y entrevistas semiestructuradas a expertos en derecho penal, género y violencia de género en Ecuador. Se realizaron análisis comparativos de legislaciones, revisión sistemática de la literatura y análisis de contenido de casos de violencia vicaria. Resultados: La investigación reveló que la violencia vicaria es una forma grave de violencia de género que afecta a mujeres y niños en Ecuador, con consecuencias devastadoras en su integridad física, psicológica y emocional. Se identificó la importancia de promover campañas de sensibilización y concienciación pública sobre este fenómeno. Conclusión: La inclusión de la violencia vicaria en la legislación ecuatoriana es crucial para garantizar la protección de las víctimas y promover una cultura de respeto y equidad de género en la sociedad. Se recomienda la implementación de estrategias de detección temprana, capacitación especializada y coordinación interinstitucional para abordar eficazmente este problema. Área de estudio general: Derecho Procesal Penal y Litigación Oral. Área de estudio específica: Derecho Penal y Violencia de Género