Maxillary osteonecrosis of the jaw. A multidisciplinary approach, communication strategies, and technological tools for prophylaxis
Authors:   Faculty of Dental Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu-Mures, Targu Mures, Romania, Golu Mihai Vlad , Bogozi Balint Botond ,   Faculty of Dental Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu-Mures, Targu Mures, Romania, Petrovan Cecilia ,   Faculty of Dental Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu-Mures, Targu Mures, Romania, Bereczki Temistocle Despina ,   Faculty of Dental Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu-Mures, Targu Mures, Romania, Guzun Sergiu ,   Faculty of Dental Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu-Mures, Targu Mures, Romania, Ormenisan Alina ,   Faculty of Dental Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu-Mures, Targu Mures, Romania
Published: April 2024

Background. Maxillary osteonecrosis, particularly medication-related osteonecrosis of the jaw (MRONJ), necessitates prompt identification and a comprehensive approach for effective management. Early diagnosis and proactive dental care are crucial in mitigating the complications associated with this condition. Aims. This study aims to outline the importance of early detection, multidisciplinary collaboration, patient education, and proactive dental care in the management of maxillary osteonecrosis. Methods. The study emphasizes the utilization of standardized medical letters to facilitate communication between prescribing physicians and dentists, while ensuring the timely exchange of essential patient information. Additionally, patient education plays a pivotal role, with the distribution of informative leaflets at the initiation of Bone Modifying Agents (BMA) treatment, emphasizing the risks associated with MRONJ and the significance of maintaining oral health and making appropriate lifestyle choices. Results. Dentists are key stakeholders in the prophylaxis of MRONJ, undertaking primary and secondary prevention measures. Primary prophylaxis encompasses various dental procedures aimed at reducing bacterial load and mucosal irritation. Secondary prophylaxis involves educating patients on maintaining optimal oral health and adopting lifestyle modifications. Furthermore, an Android application assists dentists in assessing MRONJ risk factors and making informed treatment decisions based on factors such as BMA type, dose, duration of administration, and the presence of dental and general risk factors. Conclusions. In conclusion, a proactive approach to managing Maxillary Osteonecrosis involves early detection, multidisciplinary collaboration, patient education, and proactive dental care. By integrating standardized communication tools, patient education materials, and risk assessment technology, healthcare providers can optimize patient outcomes and minimize the incidence and severity of MRONJ complications.