bluuebunny/crossref_metadata_2025 huggingface dataset:
Fuzzy logic based risk assessment system giving individualized advice for metabolic syndrome and fatal cardiovascular diseases
Authors: Korkmaz Hayriye , Canayaz Emre , Birtane Akar Sibel , Altikardes Zehra Aysun
Published: April 2019

In 2005, global cardiovascular diseases caused 30% of deaths in Europe, which is 46% of total deaths for all death groups. Today, according to the International Adult Diabetes Federation, 20% to 25% of the adult population in the world has Metabolic Syndrome. Turkish Statistical Institute claims that in Turkey 408782 people died of circulatory system diseases in 2016 and it is expected that numbers will dramatically increase. In 2003, total worldwide healthcare budget of Diabetes Mellitus was up to 64.9 billion International Dollars with the continuing rise in prevalence, it is expected that total costs will increase to 396 billion International Dollars by 2025.

The main purpose of this study was to present a clinical decision support system that calculates Metabolic Syndrome existence and evaluate HeartScore risk level for Turkish population. The second objective was to create a detailed personal report about individual’s risk level of Metabolic Syndrome and HeartScore and give advice to him/her to reduce it. The fuzzy logic risk assessment system (FLRAS) was formed in LabVIEW graphical development platform according to International Diabetes Federation and European Heart Journal’s criteria. Mamdani type fuzzy logic sets were identified for each input variable and membership functions were assigned depending on the magnitude of the input limits. System’s performance was tested on 96 (72 females, 24 males) patient data. Results show that the proposed system was able to evaluate the Metabolic Syndrome risk with 0.9285 specificity, 0.92708 accuracy and 0.925 sensitivity.
A novel analytical method of TFMPP and mCPP in fluids of drug addicts using LLE-GC/NPD
Authors: Ren Yifei , Du Junyi , Du Xianchao , Xin Guobin , Chang Jing , Zhou Hong , Hao Hongxia
Published: April 2019

In recent years, drug-abuse problem is growing by leaps and bounds all over the world. The master minds spearheading its proliferation among the youth are difficult to identify, so drug-abuse case has become a hard nut to crack even with the help of best international experts in forensic science and criminology. Because most nations have tightened their controls on traditional drugs, the younger generation is now hooked onto new-type drugs: 1-(3- trifluoromethylphenyl) piperazine (TFMPP), 1-(3-chlorophenyl) piperazine (mCPP) and other new piperazine-drugs, acting as hallucinogens like ‘ecstasy’, are being consumed by vulnerable masses all over the world. However, only few research studies have focused on developing highly effective detection methods for TFMPP and mCPP in biological fluids; the number of detection methods for these new-type drugs is almost nil in China. Therefore, it is difficult to detect and prevent drug abuse cases related to piperazine drugs in China. There is an urgent need to develop some simple, fast, and reliable methods for detecting piperazine-drugs in vulnerable masses. Thus, the development of novel detection methods with high sensitivity and selectivity is a difficult task for the officials working in the department of forensic science in China. In this work, a new method was developed for the detection of piperazine derivatives: it was performed under the various specific conditions required for conducting chromatography and mass spectrometry analysis. With this novel method, TFMPP and mCPP was successfully detected with high accuracy in various biological samples. By comparing the purification effect of different solid-phase extraction columns for TFMPP and mCPP in biological fluids (urine and blood), we confirmed the validity of the novel method. In addition, this method has good linear relationship and a low detection line when GC/MS was performed for detecting TFMPP, mCPP in the biological fluids (urine and blood). It is a simple, reproducible method that is highly specific in the detection of piperazine-drugs. Thus, it is indeed a reliable method in forensic science.
Survival rate prediction of breast cancer patients of 0-IV stages with and without radiotherapy via a revised Taylor series expansion algorithm: A population-based study in Taiwan
Authors: Chiu Shao-Wen , Peng Jia-Feng , Wang Tzu-Hwei , Pan Lung-Fa , Pan Lung-Kwang
Published: April 2019

BACKGROUND:

The morbidity of breast cancer has continuously achieved a global topicality. In particular, during the last decade several ten thousand female adults in Taiwan have been confirmed as breast cancer patients.

OBJECTIVE:

To predict the survival rate of breast cancer patients at various (0-IV) stages and provide efficient assessment of proposed radiotherapy for patients.

METHODS:

The prediction algorithm proposed is based on the revised hit and target model and implies the application of Taylor series expansion to the population-based survey dataset. The proposed algorithm features a specific function comprising a single simple exponential term [Formula: see text] to imply the fundamental degradation of patient’s health multiplied by an additional term [Formula: see text], which specifies the recovery effect of a particular therapy.

RESULTS:

Its calculated values for breast cancer patients who undergone radiotherapy at different stages 0-IV were {0.0029, 0.0066, 0.0178, 0.0475, 0.1785} yr[Formula: see text], respectively, while those for corresponding groups of patients with no radiotherapy were assessed as {0.0072, 0.0137, 0.0264, 0.0913, 0.2425} yr[Formula: see text].

CONCLUSIONS:

The revised algorithm successfully interpreted the breast cancer patients’ survival rate at stages 0-IV and evaluated the necessity of radiotherapy for patients at various stages as well.
Inverse kinematic analysis and trajectory planning of a modular upper limb rehabilitation exoskeleton
Authors: Li Ge , Fang Qianqian , Xu Tian , Zhao Jie , Cai Hegao , Zhu Yanhe
Published: April 2019

BACKGROUND:

Stroke is the most prevalent neurological disease and often leads to disability. Stroke can affect a person’s daily life, for example, its typical feature is the decline in the patient’s upper limbs. In order to reduce the sports injury of stroke patients, the best method is to carry out certain rehabilitation training.

OBJECTIVE:

In this paper, inverse kinematic analysis and trajectory planning of a modular upper limb rehabilitation exoskeleton are proposed.

METHODS:

The reverse coordinate system method is applied to solve inverse kinematics of the exoskeleton with a non-spherical joint in the wrist. For verifying the effectiveness of the algorithms, the smooth round-trip trajectory movement in joint place is designed and simulated.

RESULTS:

The reverse coordinate system method can simplify the calculation process compared with the normal coordinate system. Smooth round-trip trajectory planning is simulated to generate a smooth trajectory curve.

CONCLUSIONS:

The developed inverse kinematics algorithm and trajectory planning method are effective.
Ultrawide-angle optical system design for light-emitting diode-based ophthalmology and dermatology applications
Authors: Choi Hojong , Jo Joohyun , Ryu Jae-Myung , Yeom Jung-Yeol
Published: April 2019

BACKGROUND:

Compared to laser, light-emitting diodes – non-coherent and divergent light sources requires that the developed optical system support steering and focusing of light on the desired target when acquiring information regarding human tissues.

OBJECTIVE:

A new optical system with an ultrawide angle was designed to cover large areas of the eye, including facial areas near the eye, in order to overcome the limited field of view of optical systems used for ophthalmology and dermatology applications.

METHODS:

To achieve a compact and handheld optical system for ophthalmology and dermatology applications, a contrast auto-focus (AF) method must be used, and the weight reduction of the AF group is considered during the design process to satisfy the effective focal length (EFL), back focal length (BFL), and front focal length (FFL) in the proposed optical system using Gaussian-bracket method.

RESULTS:

The designed optical system can focus from infinity to a magnification of [Formula: see text]0.19 times, representing a distance of 114.359 mm from the first surface of the optical system to the object. The AF lens moving distance from infinity to the minimum distance is approximately 4.984 mm. The full width at half maximum (FWHM) values of the red, green, and blue light-emitting diodes were 16 mm, 35 mm, and 22 mm, respectively.

CONCLUSIONS:

We have designed an ultrawide-angle optical system for compact optical systems that are suitable for high-performance ophthalmology and dermatology applications.
Development of a visual information to auditory information transformation system for ambulation assistance
Authors: Kim Jung-Hun , Park Ji-Eun , Ji In-Hee , Won Chul-Ho , Lee Jong-Min , Jo Jin-Ho , Park Yu-Jin , Nah Jae-wook
Published: April 2019

BACKGROUND:

Assistant equipment for the visually impaired has a white cane. If the information in the three-dimensional space is transmitted by sound, the blind can draw a three-dimensional space.

OBJECTIVE:

This study developed “Visual System,” an ambulation aid/guide for the blind that transforms visual-spatial information into auditory information, and verified its utility. Unlike conventional systems, which are in essence simple collision-warning systems, Visual System helps the visually impaired to recreate their surroundings and to be cognizant of the location and proximity of obstacles.

METHODS:

Ten subjects with normal vision (mean age: 32.4 years; male-to-female ratio: 6 to 4) were selected for blind tests. The subjects were instructed to detect and avoid obstacles presented in various three-dimensional settings. Prior to the tests, experiments were conducted to determine the distance to each subject. Upon completion of Visual System-based detection training, obstacles were presented and tests conducted. For evaluation, the subjects’ vertical position detection, horizontal position detection, distance detection, and overall performance success were each evaluated.

RESULTS:

The total performance scores ranged between 88 (lowest) and 100 (highest), with a mean score of 91.5.

CONCLUSIONS:

The results indicate that Visual System as a product can assist the visually impaired in their daily functioning.
Predicting subcellular localization of multisite proteins using differently weighted multi-label k-nearest neighbors sets
Authors: Jiang Zhongting , Wang Dong , Wu Peng , Chen Yuehui , Shang Huijie , Wang Luyao , Xie Huichun
Published: April 2019

BACKGROUND:

For a protein to execute its function, ensuring its correct subcellular localization is essential. In addition to biological experiments, bioinformatics is widely used to predict and determine the subcellular localization of proteins. However, single-feature extraction methods cannot effectively handle the huge amount of data and multisite localization of proteins. Thus, we developed a pseudo amino acid composition (PseAAC) method and an entropy density technique to extract feature fusion information from subcellular multisite proteins.

OBJECTIVE:

Predicting multiplex protein subcellular localization and achieve high prediction accuracy.

METHOD:

To improve the efficiency of predicting multiplex protein subcellular localization, we used the multi-label k-nearest neighbors algorithm and assigned different weights to various attributes. The method was evaluated using several performance metrics with a dataset consisting of protein sequences with single-site and multisite subcellular localizations.

RESULTS:

Evaluation experiments showed that the proposed method significantly improves the optimal overall accuracy rate of multiplex protein subcellular localization.

CONCLUSION:

This method can help to more comprehensively predict protein subcellular localization toward better understanding protein function, thereby bridging the gap between theory and application toward improved identification and monitoring of drug targets.
A three-dimensional finite element analysis of the effect of archwire characteristics on the self-ligating orthodontic tooth movement of the canine
Authors: Cai Yongqing
Published: April 2019

BACKGROUND:

In orthodontics, the tooth movement is a biologic reaction to applied force systems, brackets, archwires, and periodontium tissue.

OBJECTIVE:

To investigate the effects of the various archwire characteristics like the friction coebetween bracket and archwire, the cross-section shape, and the cross-section dimension, on the displacement and the periodontal ligament (PDL) stresses of canine’s movement in a self-ligating treatment using the finite element (FE) analysis method.

METHODS:

Models of teeth and their supporting tissues, brackets and archwires were constructed. Ten kinds of archwires were used for the simulation.

RESULTS:

Considering the translation movement, the maximum displacement, highest stress, and [Formula: see text] increased with an increase in the cross-section area. The maximum displacement and highest stress increased with an increase in the friction coefficient. The [Formula: see text] values increased with an increase in the friction coefficient in the round archwires, while decreased with an increase in the rectangular archwires. However, these change tends were different in rotation and inclination movement.

CONCLUSION:

The archwire characteristics (round archwire, rectangular archwire, cross-section area, and friction coefficient) exhibited different effects on the tooth translation, rotation, and inclination. Our results can assist in the improvement of the self-ligating orthodontic treatment.
Study on the prediction of the contamination symptoms in the fermentation process of Chlortetracycline based on soft sensor modeling method
Authors: Sun Yumei , Tang Lingtong , Sun Qiaoyan , Wang Meichun , Han Xiang , Chen Xiangguang
Published: April 2019

BACKGROUND:

How to accurately predict the occurrence of contamination in the fermentation process of Chlortetracycline? How to prompt field operators to take effective measures in time? This is a difficult problem that the fermentation process of Chlortetracycline has not been solved well.

OBJECTIVE:

The aim of this paper is to effectively predict whether the fermentation process of Chlortetracycline is contaminated or not.

METHODS:

A Gaussian process regression soft sensor modeling method with real time integration learning is studied in depth by combining two local learning strategies, namely just-in-time learning (JITL) method and integrated learning method, and a multi-model weighted Gaussian process regression (MWGPR) soft sensor modeling method based on real-time integration learning is proposed in the paper. This soft sensing method was used to study the relationship between the viscosity of fermentation broth and the contamination in fermentation process. A soft-sensing model based on the viscosity of fermentation broth for predicting the signs of contamination is established.

RESULTS:

The validity of this method is verified by field data. The experimental results demonstrate that the soft sensing model proposed in this paper can effectively determine whether the fermentation broth is infected by hybrid bacteria.

CONCLUSIONS:

The method proposed in this paper is innovative and practical so that field operators can issue early warning and take effective measures.
A hierarchically trained generative network for robust facial symmetrization
Authors: Zhang Shu , Wang Ting , Peng Yanjun , Dong Junyu
Published: April 2019

Face symmetrization has extensive applications in both medical and academic fields, such as facial disorder diagnosis. Human face possesses an important characteristic, which is as known as symmetry. However, in many scenarios, the perfect symmetry doesn’t exist in human faces, which yields a large number of studies around this topic. For example, facial palsy evaluation, facial beauty evaluation based on facial symmetry analysis, and many among others. Currently, there are still very limited researches dedicated for automatic facial symmetrization. Most of the existing studies only utilized their own implantations for facial symmetrization to assist their interdisciplinary academic researches. Limitations thus can be noticed in their methods, such as the requirements for manual interventions. Furthermore, most existing methods utilize facial landmark detection algorithms for automatic facial symmetrization. Though accuracies of the landmark detection algorithms are promising, the uncontrolled conditions in the facial images can still negatively impact the performance of the symmetrical face production. To this end, this paper presents a joint-loss enhanced deep generative network model for automatic facial symmetrization, which is achieved by a full facial image analysis. The joint-loss consists of a pair of adversarial losses and an identity loss. The adversarial losses try to make the generated symmetrical face as realistic as possible, while the identity loss helps to constrain the output to have the same identity of the person in the original input as much as possible. Rather than an end-to-end learning strategy, the proposed model is constructed by a multi-stage training process, which avoids the demand for a large size of the symmetrical face as training data. Experiments are conducted with comparisons with several existing methods based on some of the most popular facial landmark detection algorithms. Competitive results of the proposed method are demonstrated.
Experimental study on healthy volunteers based on magnetic induction brain edema monitoring system
Authors: Xu Jia , Li Gen , Zhao Shuanglin , Chen Mingsheng , Chen Jingbo , Xu Lin , Wang Feng , Bai Zelin , Qin Mingxin , Sun Jian
Published: April 2019

BACKGROUND:

Cerebral edema is a common secondary disease after stroke. It is very important to realize real-time continuous monitoring of cerebral edema for stroke patients.

OBJECTIVE:

A non-contact magnetic induction phase shift (MIPS) detection system is used to monitor the change of global brain electrical conductivity during cerebral edema.

METHODS:

In order to verify the feasibility of this system monitoring, we carry out salt solution simulation experiments and healthy people breath holding experiments. As a comparison of later clinical experiments, 13 young healthy volunteers aged 22–35 are selected for this study to carry out a 10 minute/time monitoring experiment.

RESULTS:

It is found that the MIPS values measured by the salt solution of edema and the salt solution of bleeding are significantly different. The results show that the MIPS value of healthy young people is in a stable state with an MIPS mean value of 1.106 ([Formula: see text] 0.736)[Formula: see text]. Compare it with the monitoring results of a cerebral edema patient. The MIPS of patient fluctuates greatly, and the changes of MIPS and intracranial pressure show consistent trend at the peak of the edema period.

CONCLUSIONS:

We preliminarily verify that the system can be used for cerebral edema monitoring.
Lower extremity kinematics during forward heel-slip
Authors: Kim Sukwon , Joo Kyung-Sook , Liu Jian , Sohn Jee-Hoon
Published: April 2019

BACKGROUND:

Most fall intervention studies attempted to improve the mobility, range of motion of upper and lower extremities, or all major muscle strengths. Yet, there has been little effort to identify movements or actions that may be mainly responsible for recovering from a slipping. It was imperative to link lower extremity kinematics in conjunction with the functional anatomy of lower extremity muscles during forward heel-slipping to identify what muscles should have been activated substantially if a person would have recovered from forward heel-slipping.

OBJECTIVE:

The present study investigated lower extremity movements, such as the ankle, knee, and hip rotations, which could contribute to falls from forward heel-slipping. Determining changes in positions of foot, shank, and thigh during slipping would provide information to develop the optimal training regimen or interventions that may be effective for improving a chance to recover from the postural disturbance.

METHODS:

Twenty healthy adults (24–68 years old) participated in this experiment. Among twenty participants, only eight participants’ data were analyzed in this study. The 3D position data were used to compute the sagittal foot, shank, and thigh angles and frontal thigh angle.

RESULTS:

The study results indicated that, during the period of slipping, the angles of the segments of the slipping leg were different from that of the foot, shank, and thigh when walking ordinarily over the dry surface in the present study.

CONCLUSIONS:

The characteristics or differences in the angular kinematics of lower extremity during unexpected slips in the present study demonstrate possible causes for slip-induced falls.
The effects of dexamethasone on 17β-HSD1 levels at the rat optic nerve
Authors: Liu Chuanzhi , Xu Guozhong , Gong Ping , Wang Zuobin
Published: April 2019

Dexamethasone (DEX) is associated with many inflammation and metabolic diseases. We analyzed the effects of DEX on the expression of estrogen metabolism enzyme 17[Formula: see text]-HSD1 at the optic nerve. Rats were treated with different concentrations of intraperitoneal DEX. Western Blot analysis showed that 17[Formula: see text]-HSD protein was expressed in the optic nerve tissue. The enzyme was detected by immunohistochemistry on the terminal foot of Muller cells from the ganglion cell layer of rat retina. ELISA analysis showed that the 17[Formula: see text]-HSD1 protein expression of DEX-treated group is 2.4 fold comparing to the control group. The results indicated that DMXS sodium phosphate might modulate the expression of 17[Formula: see text]-HSD1 protein in optic tissue. This study sheds light on understanding of the relationship among DEX, 17[Formula: see text]-HSD presence and distribution of visual neural systems. At the same time, DEX treatment affects the athletic ability and memory of the animals. Compared with the control group, the experimental group showed slow response to stimulation, inertia, depression, cowardice and lack of appetite. The results of ethology experiments showed that all the parameters decreased by 15–30%.
Study on the mechanism of TMRK electroacupuncture in repairing synaptic plasticity in amygdala and hippocampus to relieve fear memory in PTSD rats
Authors: Li Mi , Li Kai , Zhang Hong , Jiang Yong
Published: April 2019

BACKGROUND AND OBJECTIVE:

Post-traumatic stress disorder (PTSD) is a chronic mental disorder caused by mental or psychological trauma after sudden events of a catastrophic or threatening nature. Synaptic plasticity is the core mechanism of PTSD and the main point of treatment of this disease.

METHODS:

Male Sprague Dawley rats were randomly divided into blank control (Ctrl), SPS (single-prolonged stress) model, SPS&S model (SPS and foot electric shock), SPS+EA (SPS plus electroacupuncture), and SPS&S+EA groups. Tranquilize Mind and Regulate Kidney (TMRK) electroacupuncture method was performed in each rat in the SPS+EA and SPS&S+EA groups, the treatment lasted for 20 minutes per day, simultaneously for 3 consecutive weeks. Behavioral evaluations, molecular tests, electron microscopy, electrophysiological testing were conducted following the treatment.

RESULTS:

First, electro-acupuncture can significantly improve the PTSD-like symptoms. Second, electro-acupuncture can up-regulate the long-term potentiation (LTP) in hippocampus, repair the synaptic morphology and improve BDNF levels in amygdala and hippocampus. Third, electroacupuncture can significantly up-regulate SYN, GAP43, and PSD95 protein levels and mRNA expression in amygdala and hippocampus.

CONCLUSIONS:

The effect of TMRK electro-acupuncture method on the regression of fear memory of PTSD rats may be through its repair of synaptic plasticity in amygdala and hippocampus.
HYDROPHOBIC COATINGS ON CELLULOSE MATERIALS
Authors: Baranov O. V. , Komarova L. G. , Rushevskaya A. V. , Gomzayk V. I.
Published: April 2019

A new hydrophobizator - tetra(ethoxy)di(octyl)disiloxane (TEDODS) - was synthesized in an ethanol solution at boiling point for 6 hours and characterized by NMR and IR spectroscopy. New hydrophobic coatings based on this compound were obtained under mild conditions by direct chemical modification of the surfaces of the cellulose materials (textile of different composition). The formation of a modified layer on the materials surface occurs due to the interaction of the ethoxy groups of the modifier and the hydroxyl groups of cellulose followed by heat treatment to fix it on the materials surface. The optimal conditions for obtaining the coatings were determined: 8% TEDODS weight gain with maximum hydrophobicity, with a wetting angle of 135°. The properties of the modified cellulose materials were studied (hydrophobicity, moisture absorption, etc.). The efficiency of using tetraethoxydioctyldisiloxane as a hydrophobizator when the content from 1% and a relatively small thickness of the coating of 2 microns was shown. It was found that hydrophobic coatings on the surface of cellulosic materials have little effect on moisture absorption and breathability of the original tissue.
PRODUCTION OF DISPERSED NICKEL POWDER IN ELECTROCHEMICAL PROCESSING OF A RENIUM-CONTAINING HEAT-RESISTANT ALL
Authors: Chernyshova O. V. , Usoltseva G. A. , Baykonurov E. G. , Drobot D. V.
Published: April 2019

The article is devoted to the substantiation of the proposed technological scheme of electrochemical processing of rhenium-containing heat-resistant alloy ZhS32-VI of composition (mass %): Re - 4.0; Co - 9.3; W - 8.6; Y - 0.005; Lа - 0.005; Al - 6.0; Cr - 5.0; Tа - 4.0; Nb - 1.6; Mо - 1.1; С - 0.16; B - 0.15; Cе - 0.025, Ni - 60.05 to obtain nickel-containing cathode deposits. The results of studying the composition, surface morphology and granulometric analysis of cathodic precipitates obtained during the electrochemical processing of the spent heat-resistant alloy ZhS32-VI with the use of acid electrolytes are presented. Anodic dissolution of ZhS32-VI was performed in the galvanostatic mode. The effect of the electrolyte composition on the process parameters (current yield, distribution of alloy components between the electrolysis products, particle size distribution of the cathode product), electrochemical processing of this alloy were established. It is shown that depending on the nature of the electrolyte, cathode deposits of different chemical and phase composition can be obtained. They differ in the size and morphology of the surface. It has been established that the value of the cathode precipitate grains obtained in acid electrolytes is almost the same: 99% of the cathode precipitate grains are in the range from 0.04 to 0.60 μm. The main difference is a slight increase in the amount of fine fraction when sulphosalicylic acid is added to the electrolyte. All the cathodic deposits obtained have a dendritic structure, the development of which depends on the nature of the electrolyte, the precipitates obtained with the use of a nitrate electrolyte having the most developed structure and the smallest particle size.
INTEGRAL TRANSFORMATION IN A PARTIALLY BOUNDED REGION WITH A RADIAL THERMAL FLOW
Authors: Kartashov E. M.
Published: April 2019

A mathematical theory is developed for constructing integral transformations in a partially bounded region with a radial heat flow - a massive body bounded from the inside by a cylindrical cavity. Constructed: an integral transformation, the image of the operator on the right side of the equation of unsteady heat conduction, the inversion formula for the image of the desired function. The proposed approach favorably differs from the classical theory of differential equations of mathematical physics for the construction of generalized integral transformations based on the eigenfunctions of the corresponding singular Sturm-Liouville problems. The developed method is based on the operational solution of the initial boundary problems of unsteady heat conduction with an initial function of a general form L2(r0,∞) belonging to the r > r0 region and homogeneous boundary conditions and is associated with the calculation of the Riemann-Mellin contour integrals from images containing various combinations of modified Bessel functions. At the same time, for the above-mentioned region, the method of Green's functions was developed by constructing integral representations of analytical solutions of the first, second and third boundary value problems through inhomogeneities in the initial formulation of the problem (boundary conditions, source function in the initial equation). Mathematical models for finding the corresponding Green's functions are formulated, and functional relations of all three Green functions included in the presented integral formula are written out with the help of the developed theory of integral transformations. The functional relations constructed in the article can be used when considering numerous special cases of practical thermal physics. The specific possible applications of the presented results in many areas of science and technology are given.
DETECTION OF HYDROPEROXIDES IN SOLUTIONS OF PHOTOOXIDIZED PSORALEN
Authors: Skarga V. V. , Nevezhin E. V. , Matrosov A. А. , Negrebetsky V. V. , Malakhov M. V.
Published: April 2019

Photooxidized psoralen solutions possess a variety of biological effects, which implementation mechanism may presumably involve hydroperoxides. Here, the hydroperoxide content in photooxidized psoralen solutions was assessed using photometric FOX assay (from Ferrous Oxidation + Xylenol Orange). FOX reagent with 10× content of Xylenol Orange, modified for quantitative analysis of up to 50 μM of hydroperoxides in aqueous phase was used in experiments. During photooxidation of 0.1 mM psoralen in phosphate buffer solution, hydroperoxide production increases with dose of UVA irradiation (~2.5 μM eq. of H2O2 for dose of 252 kJ/m2 and ~11 μM eq. of H2O2 for dose of 1512 kJ/m2) and reaches ~16.5 μM eq. of H2O2 at the highest dose investigated (3024 kJ/m2). A comparison of kinetics of psoralen photolysis and hydroperoxide generation allows us to suggest that generation of hydroperoxide results from the secondary photochemical processes involving psoralen photoproducts, presumably from photoinduced autooxidation of aldehydic photoproducts of psoralen.
DEVELOPMENT OF TECHNOLOGY FOR PRODUCTION OF PLASTICIZERS ON THE BASIS OF TRIMETHYLOLPROPANE
Authors: Aleksandrov A. Yu. , Krasnykh E. L. , Levanova S. V. , Glazko I. L. , Lukin O. D.
Published: April 2019

Polyhydric alcohols - neopolyols and their derivatives due to the nature of the structure have a row of unique properties - high thermal stability, moisture resistance, chemical resistance and are widely used in the production of synthetic oils, resins, varnishes, surfactants and plasticizers. Esters of neopolyols with several ester groups have excellent characteristics at low temperatures, as well as high environmental friendliness, which meets modern requirements. The variation in the production of esters of neopolyols, alcohol and acid components in various combinations allows to obtain a wide range of products with different characteristics and consumer properties. Currently, neopolyol esters are not produced in Russia. However, the technical capabilities of the development of R-Oxo technology based on natural gas are not in doubt, which will allow in the near future to organize its own production of neopolyol esters for the production of high-tech materials. In the present work, the possibility of obtaining plasticizers based on trimethylolpropane esters and C2-C5 acids of various structures was investigated. Samples of 7 trimethylolpropane triesters were synthesized and their certain physicochemical properties were determined. It is shown that the most promising is the synthesis of a plasticizer using acetic acid. Conducted kinetic studies on the esterification of trimethylolpropane with acetic acid. A differential method was used to estimate the reaction rate from the initial consumption rates of acetic acid. The first orders of reaction are determined by alcohol and catalyst under the conditions studied; the value of the observed activation energy of the obtained reaction of the pseudo-second order, in the temperature range of 80-115 °C, was 57.9±8.1 kJ/mol. The results obtained allow us to recommend the conditions for the implementation of the process in the industry.
Citizenship Jurnal Pancasila dan Kewarganegaraan
Authors: Multazam Muhammad Tanzil
Published: April 2019

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PENERAPAN ALGORITMA K-MEANS UNTUK PENGELOMPOKAN DAERAH RAWAN BENCANA DI INDONESIA
Authors: Siregar Amril Mutoi
Published: April 2019

Indonesia is a country located in the equator, which has beautiful natural. It has a mountainous constellation, beaches and wider oceans than land, so that Indonesia has extraordinary natural beauty assets compared to other countries. Behind the beauty of natural it turns out that it has many potential natural disasters in almost all provinces in Indonesia, in the form of landslides, earthquakes, tsunamis, Mount Meletus and others. The problem is that the government must have accurate data to deal with disasters throughout the province, where disaster data can be in categories or groups of regions into very vulnerable, medium, and low disaster areas. It is often found when a disaster occurs, many found that the distribution of long-term assistance because the stock for disaster-prone areas is not well available. In the study, it will be proposed to group disaster-prone areas throughout the province in Indonesia using the k-means algorithm. The expected results can group all regions that are very prone to disasters. Thus, the results can be Province West java, central java very vulnerable categories, provinces Aceh, North Sumatera, West Sumatera, east Java and North Sulawesi in the medium category, provinces Bengkulu, Lampung, Riau Island, Babel, DIY, Bali, West Kalimantan, North Kalimantan, Central Sulawesi, West Sulawesi, Maluku, North Maluku, Papua, west Papua including of rare categories. With the results obtained in this study, the government can map disaster-prone areas as well as prepare emergency response assistance quickly. In order to reduce the death toll and it is important to improve the services of disaster victims. With accurate data can provide prompt and appropriate assistance for victims of natural disasters.
SISTEM INFORMASI GEOGRAFIS RUTE ANGKUTAN UMUM MELALUI PENERAPAN GOOGLE MAP API (STUDI KASUS: KOTA CIREBON)
Authors: Suarna Nana
Published: April 2019

Transportasi memegang peran kunci dalam menggerakkan roda perekonomian. Informasi mengenai angkutan umum di Kota Cirebon sangatlah minim dan jauh dari sentuhan teknologi, penyebab utama permasalahan masyarakat Kota Cirebon yaitu tidak terlalu minat dengan angkutan umum, menyebabkan pendatang enggan bertanya dengan alasan kepercayaan atau malu dan mengalami kebingungan ketika akan menaik angkot, sehingga terjadi penumpukan kendaraan yang melatarbelakangi kemacetan di jalan pada jam-jam tertentu. Metode yang menjadi dasar dalam perancangan SIG ini adalah melalui pendekatan Google Map Api yang dapat menemukan jalur angkot tercepat di Kota Cirebon dengan menyertakan faktor kecepatan dan waktu tempuh ke tempat tujuan, sehingga sistem informasi geografis yang telah dibuat dapat bermanfaat bagi masyarakat dan pemerintah setempat.Tujuan penelitian ini diharapkan dapat memberikan solusi pencarian tentang beberapa jalur transportasi angkutan umum, serta dapat menampilkan fasilitas umum seperti Mall, Rumah Sakit, Bank dan masih banyak yang lainnya yang dilewati berada berada di jalur transportasi angkutan umum. Sehingga sistem yang telah dibuat informasinya dapat bermanfaat bagi masyarakat ketika ingin bepergian.
STRATEGI PENGEMBANGAN EKOWISATA KARST DI DUSUN RAMMANG-RAMMANG KABUPATEN MAROS
Authors: Djafar Muliana , Mappiasse Muh Faisal
Published: April 2019

Ekowisata merupakan suatu bentuk perjalanan wisata ke areal alami yang dilakukan dengan tujuan mengkonservasi lingkungan dan melestarikan kehidupan serta kesejahteraan penduduk setempat.  Penelitian ini bertujuan:  (1) mengidentifikasi potensi wisata yang ada pada Dusun Rammang-Rammang(2) menyusun strategi pengembangan ekowisata karst di Dusun Rammang-Rammang.Pendekatan penelitian ini kualitatif dengan teknik analisis data yang digunakan deskriptif kualitatif dan SWOT. Pengumpulan data melalui observasi lapangan,wawancara dan studi literatur.Hasil penelitian menunjukkan bahwa keragaman obyek wisata yang terdapat pada Dusun Rammang-Rammang sangat beragam, dimana dapat diketahui dengan teridentifikasinya potensi-potensi wisata yang terdapat pada kawasan tersebut, baik secara fisik, biologi maupun sosial budaya. Faktor pendukung yang terdiri dari kekuatan dan peluang, yaitu: merupakan tujuan wisata yang jarang ditemui karena keindahan karst yang eksotis, memiliki obyek wisata yang beragam,meningkatkan potensi sosial yang ada serta sumberdaya alam dapat terjaga dengan baik. Sedangkan faktor penghambat terdiri dari kelemahan dan ancaman, yaitu; obyek dan daya tarik wisata belum tertata dengan baik, pengelolaan obyek wisata yang kurang professional, kurangnya fasilitas pendukung, dan terbatasnya sumber dana bantuan dari pemerintah. Hasil perhitungan matrik IFAS dan EFAS menghasilkan nilai sumbu X sebesar 1.2 dan sumbu Y sebesar 0.8. Hal ini menunjukkan posisi strategis berada pada kuadran I, dengan rumusan strategi S-O, yaitu; mempertahankan keindahan serta keunikan sumberdaya alam agar tetap terjaga,melibatkan masyarakat luar dalam pengelolaan ekowisata, pembentukan lembaga potensi ekowisata dan menambah keragaman atraksi budayayang dikemas dalam satu paket wisata.
KOMPOSISI DAN CADANGAN KARBON EKOSISTEM MANGROVE TELUK BONE, KOTA PALOPO
Authors: Karim Hadijah Azis , Ahmad Afandi , Rosdayanti Andi
Published: April 2019

Carbon storage at mangrove ecosystem is one of the largest compared between any vegetated ecosystem. Palopo City is one of the cities bordering teh Gulf of Bone and still have secondary mangrove ecosystem. This ecosystem become a good vegetated area which can provide environmental services in the form of CO2 uptake around Palopo City. This study aimed to analyze carbon storage at mangrove ecosystem at Palopo City. Furthermore, the value of carbon storage converted to CO2-eq value which described uptake at mangrove ecosystem. Method of this research is non destructive sampling and used existing allometric equations. Data collection carried out by measuring tree diameter in sampling plot 25 × 25 m with space between plot is 100 m. Result of this study showed that average of above ground carbon is 82.34±16.92 ton/ha equal to 301.90±62.03 ton/ha CO2-eq. The sequestration of CO2 based on each mangrove species at study area is Avicenia marina 55.26 ton/ha, Rhizophora apiculata 497.13 ton/ha, Rhizophora mucronata 2259.49 ton/ha, Rhizophora spp. 1975.62 ton/ha, Sonneratia alba 4268.43 ton/ha, Xylocarpus granatum 1.19 ton/ha.
Partisipasi Politik Masyarakat Dalam Diskursus Kolom Kosong Pada Pemilihan Bupati di Kabupaten Enrekang
Authors: Khaerah Nur , Junaedi Junaedi , Muslimin Muslimin
Published: April 2019

This article discusses Community Political Participation in the selection of regent and deputy regent candidates in the Enrekang Regency and to find out the efforts of the Empty column winning team in increasing the political articipation of the community to choose the empty column. The research method used is a qualitative descriptive method and using two kinds of data, namely primary data and secondary data. The results of this study indicate that the form of community political participation in the selection of the district Head and Deputy Regent of Enrekang district is the Electoral Activity, Lobbying, Organizational Activity, Contacting and Violence. Community participation in the electoral system and of course their have own reasons, star because of the political awareness of the community and most of them assume that choosing is the right of each individual so that everyone is free to choose according to their wishes without being influenced by others. The effort of the empty column winning team in increasing community participation to select the blank box is to focus on certain issues such as socializing the failure of the detention regentArtikel ini membahas tentang Partisipasi politik masyarakat dalam pemilihan calon Bupati dan Wakil Bupati di Kabupaten Enrekang dan untuk mengetahui upaya tim pemenangan Kolom Kosong dalam meningkatkan Partisipasi politik masyarakat untuk memilih Kolom Kosong. Adapun metode penelitian yang digunakan adalah metode deskriptif kualitatif dengan menggunakan dua macam data, yaitu data primer dan data sekunder. Hasil penelitian ini menunjukkan bahwa bentuk partisipasi politik masyarakat dalam pemilihan Bupati dan Wakil Bupati Kabupaten Enrekang yaitu dengan Electoral Activity, Lobbying, Organizational Activity, Contacting dan Violence. Keikutsertaan masyarakat dalam sistem pemilu dan tentunya memiliki alasan masing-masing, mulai karena kesadaran politik masyarakat. Upaya Tim Pemenangan Kolom Kosong dalam Meningkatkan Partisipasi Politik Masyarakat untuk Memilih Kolom Kosong adalah dengan memfokuskan pada isu tertentu seperti mensosialisasikan kegagalan dari bupati petahana
Pengaruh Posisi Bukaan terhadap Penghawaan Alami pada Rumah Balai Padang
Authors: Yanti Rahma
Published: April 2019

Penelitian ini bertujuan untuk mengetahui efek dari posisi dari bukaan yang ada di rumah Balai Padang. Metode yang digunakan adalah eksperimental dengan menggunakan bantuan software CFD (computational Fluid Dimension) berdasarkan persamaan Navier-Stoke, menggunakan K-Epsilon RNG. Eksperimen dilakukan dengan validasi hasil pengukuran lapangan This study aims to investigate the effect of position openings in Balai Padang house. The numerical methodology is based on solution of the Navier-Stokes equations, using K-epsilon RNG. Numerical results are validated with available field measurement data.
LEGALITAS REKOMENDASI OLEH PARTAI PERSATUAN PEMBANGUNAN (PPP) SESUAI PASAL 36 PKPU NO. 9 TAHUN 2016 TENTANG PENCOBLOSAN PEMILIHAN KEPALA DAERAH
Authors: Male Ichsan Adrias , Sahi Nirmala , Gobel Rahmat T.S
Published: April 2019

Konflik produk hukum antara surat keputusan Menteri Hukum dan HAM yang mengesahkan kepengurusan Romahurmuzy dan putusan Mahkamah Agung yang mengesahkan kepengurusan Djan Faridz menjadi objek permasalahan terkait legalitas rekomendasi manakah yang memiliki dasar hukum yang kuat untuk mengajukan calon kepala daerah sesuai amanat pasal 36 PKPU No 9 Tahun 2016.Adapun yang menjadi rumusan masalah dalam penelitian ini adalah : (1) kekuatan hukum surat rekomendasi calon kepala daerah sesuai pasal 36 PKPU No 9 Tahun 2016 Tentang Pencalonan Pemilihan Kepala Daerah; (2) konstitusionalitas surat rekomendasi yang dikeluarkan oleh kepengurusan Romahurmuzy dan kepengurusan Djan Faridz; (3) solusi untuk mengatasi dualisme kepemimpinan Partai Persatuan Pembanguan dalam memberikan rekomendasi dan dukungan terhadap pemilihan kepala daerah. Penelitian ini adalah penelitian normatif yaitu teknik atau prosedur telaah dengan berpedoman pada beberapa asas hukum, kaidah-kaidah hukum, maupun prinsip-prinsip hukum yang berkaitan dengan substansi peraturan perundang-undangan yang bersifat umum dan khusus agar dapat menjawab isu hukum yang diajukan.Hasil penelitian ini menunjukan bahwa pertama, ketentuan Pasal 36 PKPU No 9 Tahun 2016 menjelaskan bahwa dalam hal keputusan terakhir dari Menteri tentang kepengurusan Partai Politik tingkat pusat masih dalam proses penyelesaian sengketa di pengadilan, Komisi Pemilihan Umum menerima pendaftaran Bakal Pasangan Calon berdasarkan keputusan terakhir dari Menteri tentang penetapan kepengurusan Partai Politik. Dengan demikian, kekuatan surat rekomendasi yang sesuai legal-formal adalah kepengurusan Romahurmuziy dan dapat dipastikan kepengurusan yang sah sesuai ketentuan peraturan perundang-undangan adalah kepengurusan Romahurmuziy. Kedua, Dualisme Partai Persatuan Pembangunan (PPP) yang terjadi telah menimbulkan ketidakpastian hukum terkait dengan calon kepala daerah dari PPP yang mengakibatkan adanya upaya hukum untuk mendapatkan legal standing kepengurusan partai yang berhak mengusung calon kepala daerah yang pada akhirnya Mahkamah Agung mengabulkan Peninjauan Kembali kepengurusan Romahurmuziy dengan membatalkan Kasasi Mahkamah Agung Nomor 504 K/TUN/2015 Tahun 2015 yang sebelumnya dimenangkan oleh Djan fariz. Atas dasar putusan Mahkamah Agung itulah, kepengurusan Romahurmuziy adalah kepengurusan yang memiliki kewenangan untuk mengeluarkan rekomendasi pencalonan kepala daerah dan wakil kepala daerah.
Kepribadian Locus Of Control Kecerdasan Emosional Dan Iklim Kerja Terhadap Organization Citizenship Behavior Pegawai
Authors: Rismayanti Rismayanti
Published: April 2019

Rismayanti. 2018, Peranan Kepribadian Locus Of Control, Terhadap Organization Citizenship Behavior Pegawai pada Dinas Pendidikan Kebudayaan Pemuda dan Olahraga Provinsi Gorontalo.Penelitian ini bertujuan untuk mengetahui Peranan Kepribadian Locus Of Control, Kecerdasan Emosional dan Iklim Kerja Terhadap Organization Citizenship Behavior pada Dinas Pendidikan Kebudayaan Pemuda dan Olahraga Provinsi Gorontalo. baik secara simultan maupun parsial. Pengumpulan data pokok yaitu melalui daftar pernyataan/pertanyaan yang diuji melalui uji validitas dan reabilitas. Metode analisis yang digunakan adalah analisis jalur (Path Analisis) dengan terlebih dahulu memgkonversi data dari skala ordinal ke skala interval. Objek dalam penelitian ini adalah Kepribadian Locus Of Control, Kecerdasan Emosional dan Iklim Kerja Terhadap Organization Citizenship Behavior.Hasil hipotesis pertama menunjukan bahwa Kepribadian Locus Of Control (X1), Kecerdasan Emosional (X2) dan Iklim Kerja (X3) Terhadap Organization Citizenship Behavior secara simultan berpengaruh positif dan Signifikan terhadap Organization Citizenship Behavior pada Dinas Pendidikan Kebudayaan Pemuda dan Olahraga Provinsi Gorontalo sebasar 66,0%. Sedangkan 34,% dipengaruhi oleh variabel lain yang tidak diteliti dalam model penelitian ini.Hasil pengujian hipotesis kedua menunjukan bahwa Kepribadian Locus Of Control (X1) secara parsial berpengaruh positif dan signifikan terhadap Organization Citizenship Behavior (Y) sebesar 31,6%. Kecerdasan Emosional (X2) secara parsial berpengaruh positif dan signifikan Organization Citizenship Behavior (Y) sebesar 36,8% dan Variabel Iklim Kerja (X3) secara parsial berpengaruh positif dan signifikan terhadap Organization Citizenship Behavior sebesar 32,3%.