bluuebunny/crossref_metadata_2025 huggingface dataset:
A melody that sings itself
Authors: Caeiro António Castro
Published: October 2024

In his lectures on the philosophy of nature, Maurice Merleau-Ponty interprets Jakob von Uexküll’s notion of Umwelt as akin to a melody. This essay outlines von Uexküll’s perspective on the feasibility of translating non-acoustic elements (optical: colours, shapes, and figures; haptic: tactile textures, flavours, tastes, and scents) into sounds or musical notes to compose a melody. It poses several inquiries: Does the link between melody and nature render natural entities as musical notes? Do the components of an entity constitute anatomical notes in the melody that defines the entity itself? Is it conceivable to distil every moment in life into a “note” symbol on a musical scale, characterised by specific duration, pitch, and volume? Melody, rhythm, and harmony are considered sophisticated “structures” that articulate and convey the essence of nature’s existence. Moreover, every human, every living creature, be it animal or plant, possesses a subjective “biological” interiority. The inner realm of each living subject, along with the objects in the external world, are enveloped within an atmosphere—a musical Umwelt. Humans exist within this musical milieu or atmosphere.
E. M. de Melo e Castro e a “força sintetizadora da comunicação visual”
Authors: Da Costa Espada Francisco
Published: October 2024

Partindo do concretismo subjacente ao texto poético de Ernesto Manuel de Melo e Castro, e que está na origem do tratamento da linguagem a partir dos seus modos de materialização, o presente texto procura traçar um possível caminho interpretativo para a função da poesia visual determinada pelo autor, a saber: sintetizar a comunicação visual. Para tal, é explorado o percurso percorrido pelo cruzamento de sistemas sígnicos levado a cabo pela prática poética de Melo e Castro, especialmente aquela que diz respeito a questões de intermedialidade, e que se prende com o modo de materialização da densidade sígnica do fenómeno textual.
Lasofoxifene Demonstrates that Anti-estrogen Therapy Increases Immunotherapy Efficacy
Authors:   Sunvalley Communication, LLC / Onco'Zine, Hofland Peter
Published: October 2024

Eosinophils were recently identified as influential in combating tumor progression. A phenomenon called tumor-associated tissue eosinophilia (TATE) is linked to better outcomes among patients with multiple types of cancer, including colon, esophageal, gastric, oral, melanoma, and liver cancers.
Apalutamide Demonstrates Statistically Significant Improvement in Overall Survival in mCSPC
Authors:   Sunvalley Communication, LLC / Onco'Zine, Hofland Peter
Published: October 2024

Real-world evidence showed a statistically significant and clinically meaningful improvement in survival with apalutamide over enzalutamide in patients with mCSPC at 24 months.
Gelatin Gel from By-products of Sand Jellyfish (Rhopilema hispidum): Physicochemical and Biochemical Characterization
Authors: Charoenchokpanich Wiriya , Muangrod Pratchaya , Thumthanaruk Benjawan , Rungsardthong Vilai , Roytrakul Sittiruk , Charoenlappanit Sawanya , Wonganu Benjamaporn , Casanova Federico
Published: October 2024

Salted sand-type jellyfish by-products are abundant in collagen, which may be processed into gelatin to decrease food waste. From the production standpoint, various factors affect gel qualities, including raw material used, pretreatment methods, and extraction times. So far, gelatin extracted from desalted sand-type jellyfish by-products (D-SJB) must be adequately characterized. Therefore, this research aimed to characterize gelatin from D-SJB using different pretreatment methods and extraction times. D-SJB was treated with 0.2 M hydrochloric acid (acid method) and extracted for 24 h at 60 °C (SA24), the optimal gelatin extraction condition with the highest gel qualities, while the jellyfish gelatin obtained after D-SJB was treated with pepsin and extracted for 48 h had the lowest gel qualities. The viscosity, gel strength, gelling temperature, and melting temperatures of SA24 were 20.80 cP, 352.22 g, 11.97 °C, and 22.70 °C, respectively. All jellyfish gelatin’s gelling and melting temperatures ranged from 6.13−11.97 °C and 15.85−22.70 °C, exhibiting a cold set gel and unstable gels at room temperature. The different pretreatment methods and extraction times during the jellyfish gelatin production resulted in the conversion of amides A, B, I, II, and III, especially the wavenumber of the amide I increased after pepsin pretreatment and increased with longer extraction time. Twenty-one collagen subtypes in bovine, fish, and jellyfish gelatin were analyzed using LC-MS/MS. The collagen alpha-2(I) chain, a key gelatin component, was identified in all gelatins. The research novelty showed the profound characterization results of gelatin gel produced from D-SJB. However, further experiments will be needed for pilot-scale production to be used in food and non-food applications.
Cultura de Datos en Trata de Seres Humanos II: Informe Técnico de Investigación
Authors: Estrada Villaseñor Cecilia , Dubin Edelstein Adam , Aparicio Malo Jose Manuel , Verdasco Martínez Raquel
Published: October 2024

La trata de personas es reconocida mundialmente como una forma de esclavitud mo¬derna que continúa devastando vidas y comunidades. Este fenómeno delictivo no solo constituye una grave violación de los derechos humanos, sino que también representa uno de los negocios ilícitos más lucrativos a nivel global, comparado solo con el tráfico de drogas y armas. En este contexto, la recopilación y análisis de datos precisos y fiables es fundamental para comprender la magnitud y las características de la trata de personas en nuestras fronteras y para desarrollar políticas públicas efectivas. Este informe, desarrollado en el marco del proyecto «Cultura de Datos en la Trata de Seres Humanos», subraya la impor¬tancia de una cultura de datos robusta que permita no solo visibilizar este problema, sino también responsabilizar y empoderar a los actores clave en la lucha contra la trata. La Cultura de Datos en la Trata de Seres Humanos es una estrategia integral que coloca los datos en el centro de los esfuerzos para combatir la trata de personas. Al mejorar la recolección, análisis, y uso de datos, este enfoque busca no solo visibilizar el alcance real de la trata, sino también desarrollar respuestas más efectivas y coordinar mejor las acciones entre todos los actores in¬volucrados. El objetivo de este trabajo es proporcionar una visión comprensiva y detallada de la situación actual de la trata de seres humanos en España, examinando tanto las dimen¬siones cuantitativas como cualitativas de este fenómeno. A través de la metodología de Estimación de Sistemas Múltiples (MSE) y técnicas cualitativas, buscamos no solo iden¬tificar las víctimas visibles, sino también desvelar la cifra oculta de aquellas personas que aún permanecen en las sombras.
Quality of Life and Depression in Premenstrual Dysphoric Disorder and Premenstrual Syndrome Among College Students
Authors: Pathak Vijendra Nath , Anjalee K M
Published: October 2024

The symptoms before a woman’s period, Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD) involve physical and emotional aspects. PMS and PMDD differ in symptom severity. Thus, the psychological effects are considerable and affect the individual’s physical state. The present study aims to investigate the quality of life and depression among college students with PMS and PMDD. Forty clinically diagnosed females with Premenstrual Dysphoric Disorder and 40 females with Premenstrual syndromes were sampled through purposive sampling method, the age range of 16 to 21 (Mean age 18.37, SD 1.63) years from Kapurthala, Punjab.  WHO Quality of Life -BREF Hindi and Beck Depression Inventory-II were individually administered to both groups. The statistical analysis of descriptive and t-tests revealed that premenstrual dysphoric disorder exhibits a significantly low level of quality of life as compared to premenstrual syndrome. Premenstrual dysphoric disorder revealed significantly higher levels of depression as compared to premenstrual syndrome. The significant finding of the study is that adolescents with Premenstrual dysphoric disorder suffer from poor quality of life and Well-being. Study supporting female adolescents, especially those with severe Premenstrual dysphoric disorder, can enhance their quality of life and well-being through counseling, education, and lifestyle changes.
Method Development and Validation of Metformin and Gliclazide in Tablet dosage form by Micellar Liquid Chromatography
Authors: Kumar Manoj , Dhaka Monika , Pradhan Subhalaxmi
Published: October 2024

Micellar Liquid Chromatography (MLC) has emerged as a promising technique for the analysis of Pharmaceutical compounds due to its versatility, efficiency, and cost-effectiveness. In this experimental research paper, we explore the application of MLC in the simultaneous analysis of two commonly prescribed antidiabetic drugs, Metformin and gliclazide. A combination of these medicines is widely used to treat type 2 diabetes mellitus, so accurate quantification of them is essential for efficient therapeutic management. To separate the drug formulation, reversed phase liquid chromatography (RP-HPLC) was employed using surfactant solutions above Critical Miceller concentration (CMC). The mobile phase included 0.10M SDS and 10% Propanol-1, with a pH of 3.50 maintained by o-Phosphoric Acid and analysis was done using Deoxyprobe C18 column (4.6 x 150 mm, 5 µm). The separation was carried out at room temperature with a flow rate of 1.0 ml/min, and detection was performed at 228 nm. Gliclazide has a retention time of 4.46 minutes, compared to 5.57 minutes for metformin. The percentage composition of the sample under analysis ranged from 90 to 110 percent in accordance with schedule V of the Drug and Cosmetic Act. The suggested practice met ICH requirements. The method was also low-cost, easy to use, secure, and ecologically benign. It can be used to conduct standard quantitative analyses on pills that include metformin and gliclazide.
A Proteins of ANL Family FACLs and FAALs, Next Anti TB Drug Targets.
Authors: Chakraborty Ankuri , Kalam Marzuqua , Sarkar Sutanu , Roy Deotima , Bhattacharjee Momsree , Paul Devkamal , Banerjee Asesh , Gupta Dr. Prabuddha
Published: October 2024

The adenylating enzymes (AEs) of the ANL family contribute to the lipid synthesis process in Mycobacterium tuberculosis (MTB). FAALs (Fatty Acyl-AMP Ligase) and FACLs (Fatty Acyl-CoA Ligase) are members of the ANL enzyme family and are closely associated with the metabolism of mycobacterial lipids responsible for successful infections. Therefore, given their role in both biosynthesis and breakdown processes within fatty acid metabolism, these two groups of proteins might be potential drug targets. The growing abundance of structural, biochemical, and genetic information on mycobacterial FAAL and FACL enzymes could provide a solid foundation for the creation of next-generation anti-tuberculosis drugs, via rational drug designing.
Медиации статусных неравенств в здоровье: зависимость эффектов социального капитала от возраста
Authors: Русинова Нина Львовна , Сафронов Вячеслав Владимирович
Published: October 2024

Исследование посвящено проблеме социально-структурных неравенств в здоровье и воздействия на них социального капитала. Согласно результатам предыдущих исследований, с повышением образования, дохода, профессионального статуса наблюдается заметное улучшение состояния здоровья людей. Оно улучшается и при обладании индивидами социальным капиталом, в частности, когда человек получает доступ к важным ресурсам благодаря социальным связям с лицами, занимающими достаточно высокое положение в обществе. Развитие теоретических представлений о причинах неравенства в сфере здоровья в последние годы было связано с проверкой предположений, согласно которым социальный капитал может опосредовать влияние социально-экономического статуса на здоровье. Результаты эмпирического тестирования, однако, противоречивы: одни подтверждают наличие медиаций, но другие их не находят. Причем подтверждения были получены в определенных группах населения, в частности среди пожилых.
Представленный анализ российских опросных данных, собранных по Программе международного социального исследования (ISSP 2017), направлен на обоснование указанных теоретических положений и подразумевает выявление медиативных эффектов социального капитала (профессионального статуса близких и знакомых индивида) при рассмотрении образовательных, а также доходных и профессиональных неравенств в здоровье. Анализируются возрастные особенности проявления таких медиаций — возраст выступает модератором посреднических эффектов. Результаты подтверждают, что в нашей стране с полной определенностью проявляются статусные неравенства в здоровье и социальный капитал играет важную роль в его сохранении. Обнаружены непрямые эффекты социального капитала, объясняющие эти неравенства. Причем возраст действительно выступает модератором медиативного влияния социального капитала — оно практически незаметно в младших возрастах и нарастает, обретая статистическую значимость, к старшим.
Потребление новостей в сельской местности: (не)доверие и стратегии верификации информации
Authors: Петрова Дарья Вячеславовна
Published: October 2024

В статье анализируются практики медиапотребления в сельской местности в условиях возросшей на фоне кризиса потребности в информации и ограниченности ресурсов ее получения. Эмпирическим материалом служат интервью, проведенные в июле 2023 г. в деревнях Вологодской области. Результаты демонстрируют, что, несмотря на преобладание традиционных медиа, информационная среда в деревне относительно гетерогенна за счет потребления новостей из новых медиа и их дополнения межличностной коммуникацией. Выявлены комплексность феномена доверия новостям, фрагментация и дифференциация логик обоснования.
Причинами недоверия становятся противоречия между различными источниками, несовпадение новостей с восприятием человеком реальности, неудовлетворяющие его манера подачи сообщений и содержание новостей. Доверие зачастую персонифицируется, а также опирается на повторяемость информации, отражение новостей в окружающей действительности, логичность и последовательность транслирования. Декларируя недоверие новостям, информанты тем не менее продолжают потреблять подобный контент и не стремятся верифицировать его. Распространение получает «прагматичное доверие» — опора на интуицию и эвристики, а также делегирование ответственности за достоверность новостей «надежным другим», которыми выступают конкретные личности как из социального окружения опрошенных, так и со стороны авторов новостей. Выделяется роль политических предпочтений: доверие медиа становится проекцией доверия политическим институтам и отдельным персоналиям, склонности потреблять идеологически близкий контент.
Благодарность. В работе использованы результаты проекта «Повседневные поведенческие практики россиян в условиях внешних шоков», выполненного в рамках Программы фундаментальных исследований НИУ ВШЭ в 2024 г.
Singularidades en el hecho imponible, devengo y exenciones de los impuestos especiales de fabricación respecto de su configuración en la parte general del derecho tributario
Authors: Orón Moratal Germán
Published: October 2024

Los Impuestos especiales de fabricación, además de su denominación, presentan algunas especialidades respecto de las categorías generales del Derecho tributario, abordándose aquí, además de particularidades relativas a la reserva de ley y configuración del hecho imponible, supuestos gravados que no se identifican expresamente como hecho imponible, aunque lo son, y sustitutos a los que la ley no dice claramente a quien sustituyen; exenciones que no impiden el nacimiento de la obligación de pago, y que se aplican mediante devolución, incluso a quien no realizó el hecho imponible; así como devengos que pueden dejar de serlo, y consumos que no comportan el devengo.
¿Una multa por litigar? Sí, Usted ha incurrido en un abuso de la Justicia como servicio público cuando debería haber procurado la desjudicialización de su conflicto
Authors: Calaza López Sonia
Published: October 2024

La defensa técnica de la Jurisdicción civil dispositiva sube de precio. Bajo una curiosa concepción de la Justicia como servicio público, los justiciables habrán de costear privadamente (excepción hecha de quiénes puedan beneficiarse de la denominada “justicia gratuita”) un “medio adecuado de resolución de controversias” como requisito de procedibilidad, cuyo (i) incumplimiento provocará la inadmisión de la demanda y cuyo (ii) cumplimiento defectuoso (por poco “negociador”) derivará en una condena en costas y una multa por uso abusivo de la Justicia como servicio público: ¡Ahí es nada! En este trabajo se aborda la (extrema) dificultad de explicar al justiciable que (si llega a aprobarse la Ley Orgánica de medidas en materia de eficiencia del Servicio Público de Justicia y de acciones colectivas para la protección y defensa de los derechos e intereses de los consumidores y usuarios, de 22 de marzo de 2024) ya no tendrá derecho a (todo lo que) es suyo: la renuncia a una parte (de lo suyo) se impone en una clara regresión de la concepción clásica de la Justicia extraordinariamente expuesta por Ulpiano: La justicia civil dispositiva (de futuro) ya no será: la constante y perpetua voluntad de dar a cada uno su propio derecho, sino tan solo una parte de su propio derecho.
Análisis jurídico de la regla de proporcionalidad y diferimiento de la ganancia patrimonial en la donación de la empresa familiar. ¿Figuras compatibles o excluyentes?
Authors: Ferrer Vidal Diana
Published: October 2024

En las transmisiones lucrativas inter vivos de participaciones de la empresa familiar, hasta la fecha, la jurisprudencia y la doctrina ha focalizado su estudio en la fiscalidad del donatario; a saber, en la reducción en la base imponible del ISD; beneficio fiscal que parte de la exención en el IP, bonificaciones tributarias ambas que pueden ser parciales, es decir, abarcar únicamente la parte de participaciones que efectivamente están afectas a una actividad económica. Sin embargo, en sede del donante también pudiera generarse una ganancia patrimonial, la cual, según el art. 33.3c) LIRPF está diferida en la medida en que se trate de donaciones de empresas o participaciones a las que se refiere el apartado 6 del art. 20 Ley ISD. ¿Se infiere del texto legal que aplica la regla de proporcionalidad también en el IRPF del donante? ¿Hacerlo sería aplicar el argumento analógico? ¿Las consultas vinculantes de la DGT sobre el asunto pueden suponer una vulneración a la confianza legítima del contribuyente? ¿Qué papel juega la interpretación finalista del incentivo fiscal? Este artículo pretende arrojar algo de luz a la cuestión al hilo de las últimas resoluciones administrativas, proponiendo finalmente una necesaria modificación del texto legal que incluya la aplicación de la regla de proporcionalidad, también en el diferimiento de la ganancia patrimonial generada en el IRPF del donante.
La pretendida exención del Impuesto sobre Bienes Inmuebles de los partidos políticos
Authors: Polo Cañavate Joaquín Jesús
Published: October 2024

Con relación al régimen tributario propio de los partidos políticos, al que son acreedores por su especialísima naturaleza jurídica y por haberlo decidido así la Ley, surge la duda de si, entre las exenciones fiscales que se les otorgan, figura la relativa al Impuesto sobre Bienes Inmuebles, impuesto de titularidad municipal cuya exacción es obligatoria para los Ayuntamientos. La Ley Orgánica 8/2007, sobre financiación de los partidos políticos, no menciona ni tan siquiera a este impuesto al regular el régimen tributario propio de estos entes, pero, sin embargo, su remisión a la Ley 49/2002, de régimen fiscal de las entidades sin fines lucrativos, en lo no previsto en ella, hace surgir la duda de si se les aplican las exenciones previstas para las entidades no lucrativas, lo que de alguna manera supondría considerar a los partidos políticos como un tipo especial de aquellas. En este artículo se intentará desentrañar la cuestión de si los partidos políticos tienen derecho a gozar de la exención del IBI con relación a los inmuebles de los que son titulares.
Fiscalidad de los traspasos internacionales de derechos federativos de futbolistas a la luz de las Sentencias del Tribunal Supremo de 4 de marzo de 2024 (rec. 6519/2022), y 4 de abril de 2024 (rec. 7109/2022) en los Casos Neymar y James Rodríguez
Authors: Gómez Requena José Ángel
Published: October 2024

El presente trabajo analiza el alcance de la doctrina manifestada por la Sala Tercera del Tribunal Supremo en su sentencia de 4 de marzo de 2024, recurso de casación núm. 6519/2002, sobre la calificación fiscal y la tributación en el IRNR de las rentas percibidas por un club de fútbol no residente por el traspaso de los derechos federativos de un futbolista a un club de futbol residente en España (caso Neymar) y su extrapolación a la sentencia de 4 de abril de 2024, recurso de casación núm. 7109/2022 (caso James Rodríguez). La sentencia confirma la posibilidad de transmitir estos derechos y su consiguiente contenido económico. De esta manera, es posible que estas transmisiones generen rentas susceptibles de ser calificadas como ganancias patrimoniales. Estas ganancias patrimoniales pueden ser sometidas a tributación en España a través del IRNR cuando sean obtenidas por entidades deportivas no residentes siempre que el Convenio fiscal correspondiente conceda potestad tributaria a España para gravar esas ganancias de capital. La doctrina emanada de esta sentencia estima que las rentas se entienden obtenidas en España a la luz del art. 13.1.i) 2º TRLIRNR ya que los derechos federativos del futbolista deben ser inscritos en la Real Federación Española de Fútbol y van a ser utilizados y ejercitados en territorio español.
La compatibilidad con el Derecho de la Unión Europea de la limitación a la deducibilidad de intereses derivados de préstamos intragrupo. Análisis de las Conclusiones del Abogado General Sr. Nicholas Emiliou, presentadas el 14 de marzo de 2024, sobre el as
Authors: Ferreiro Serret Estela
Published: October 2024

El asunto C-585/22 se enmarca en una serie de asuntos planteados ante el Tribunal de Justicia de la Unión Europea en los que este ha tenido oportunidad de pronunciarse acerca del carácter restrictivo que pueden tener determinadas situaciones generadas como consecuencia de la interacción entre regímenes de consolidación y otras normas fiscales. Concretamente, se plantea al TJUE si la limitación a la deducibilidad de intereses derivados de préstamos intragrupo para entidades no residentes del Derecho neerlandés es compatible con el Derecho de la Unión Europea, en particular, con la libertad de establecimiento del artículo 49 TFUE. El Abogado General Sr. Nicholas Emiliou, en sus Conclusiones presentadas el 14 de marzo de 2024, sobre el asunto C-585/22, propone que el Tribunal responda que dicha normativa es compatible. Sin embargo, tras el análisis de su razonamiento junto con la jurisprudencia previa del TJUE, entendemos que el Tribunal puede desmarcarse, al menos en parte, de dicho razonamiento y, por lo tanto, llegar a una conclusión distinta.
El principio de proporcionalidad y las sanciones aduaneras (As. C-717/22 y C-372/23)
Authors: Fernández de Buján y Arranz Antonio
Published: October 2024

En los reenvíos prejudiciales As. C-717/22 y C-372/23, dos tribunales búlgaros elevan al Tribunal de Justicia sus dudas sobre la interpretación del régimen de infracciones y sanciones establecido en el Reglamento (UE) n.º 952/2013 por el que se establece el Código Aduanero de la Unión. En esencia, con sus preguntas quieren saber: a) si el dolo constituye un elemento necesario de la infracción consistente en no facilitar a las autoridades aduaneras la información prevista en el artículo 15 del Código Aduanero, relativo al suministro de información a las autoridades aduaneras; y b) si el derecho de la Unión se opone a una normativa nacional que contemple, en circunstancias como las de los litigios de origen, el decomiso de las mercancías en cuanto sanción por el incumplimiento de las obligaciones aduaneras.
La calificación como deudor del IVA al empleado que emite facturas falsas. Comentario a la STJUE de 30 de enero de 2024
Authors: González Aparicio Marta
Published: October 2024

En la Sentencia del TJUE de 30 de enero de 2024, el Tribunal interpreta el artículo 203 de la Directiva del IVA, extendiendo la posibilidad de adoptar la condición de deudor del IVA a sujetos distintos al sujeto pasivo. Particularmente, en el caso enjuiciado se examina el supuesto de un trabajador que emitió facturas falsas de IVA sin el conocimiento de su empleador, entendiendo el Tribunal que, si la entidad empleadora actuó con la diligencia debida para evitar tales actuaciones fraudulentas, la condición de deudor de IVA debe ser atribuida al trabajador.
La controvertida definición del método de cálculo de la tasa por aprovechamiento especial del dominio público por instalaciones de transporte de energía eléctrica, gas, agua e hidrocarburos
Authors: Mories Jiménez María Teresa
Published: October 2024

Los Ayuntamientos, en el uso de las competencias que les otorga la Constitución Española y la Ley Reguladora de Haciendas Locales, han encontrado en la tasa por ocupación del dominio público local por instalaciones de transporte de energía eléctrica, gas, agua e hidrocarburos una vía más para salvaguardar sus necesidades recaudatorias, escudándose en los principios de autonomía local y suficiencia financiera. Desde sus orígenes, la regulación de este tipo de tasas ha sido muy cuestionada por las empresas sometidas a ellas, generando múltiples controversias ante los tribunales, la mayoría relacionadas con su cuantificación, que han obligado a los entes locales a adaptar su normativa a la jurisprudencia del Tribunal Supremo, velando siempre por el respeto al principio de reserva de ley. En este caso, se busca garantizar que las Ordenanzas fiscales establezcan un sistema de determinación de la cuota tributaria que refleje que el valor de dicha utilidad se corresponde con el previsto en el artículo 24.1.a) del TRLRHL, de manera que los elementos de cuantificación (base imponible y tipo de gravamen) constituyan un todo coherente que se ajuste a ese parámetro de referencia.
Medailony, nekrology, vzpomínkové texty (psané třemi jubilanty a o třech jubilantech)
Authors: Hoffmannová Jana
Published: October 2024

A significant element of the “memory of the discipline” consists of shorter texts written on the occasion of a life milestone or the death of important personalities, above all biographical portraits, obituaries and commemorative texts – that is, genres of scholarly discourse which are typically placed in journals in the sections with titles such as “Notices” (and the like). This contribution focuses on the biographical portraits and obituaries written by Vladimír Šmilauer, Karel Hausenblas and Alexandr Stich, and further on the countless texts written about them by other authors. Attention is devoted first to the characteristic features and means of these genres: text titles, composition, rhetoric, and evaluative, figurative and playful expressions. Following the description of these genres is a characterization of Šmilauer, Hausenblas, and Stich, three outstanding scholars and teachers: what they had in common, where they differed, how they spoke and wrote. Their human characteristics (e.g., personal selflessness) emerge very clearly, especially from the commemorative texts, often informal and emotional, published by their students, colleagues and friends.
Příspěvek Alexandra Sticha a Vladimíra Šmilauera k výzkumu české vojenské terminologie
Authors: Ernst Josef
Published: October 2024

Alexandr Stich as well as Vladimír Šmilauer dealt with Czech military terminology, although this was not their main area of research. Both of them linguistically analyzed the work of others, namely Stich of Friedberg-Mírohorský and Šmilauer of Emil Smetánka. Stich was fascinated by Friedberg-Mírohorský’s effort because he also saw it as a political manifesto that would raise the Czech language to a higher level, and thus to the same level as the German language. For Šmilauer, who was a student of Smetánka, his work was of great importance because of its originality and systematic nature. Both Stich and Šmilauer made a thorough analysis of original sources, be it the illustrative atlas by Friedberg-Mírohorský or the set of small arms terminology, which was based on Smetánka’s work in the terminology commission after World War I.
Role Vladimíra Šmilauera v etymologickém slovníku Václava Machka
Authors: Boček Vít
Published: October 2024

This study examines both the quantitative and qualitative contribution of Vladimír Šmilauer to Václav Machek’s etymological dictionary. Appointed scientific referee, Šmilauer wrote lengthy evaluations for both editions of the dictionary, which contained hundreds of notes and suggestions for improving individual entries. In our paper we classify these comments into several groups, working mainly with the criterion of the nature of the comments (i.e. whether they concern the forms and/or meanings of words given in the entry, or the interpretation of the origin of the word) and the criterion of the acceptance of the suggestions by Machek (roughly on the axis of acceptance – alternative interpretation – rejection). Šmilauer’s reviews provide some hitherto unknown interpretations of Czech and Slovak words, and may thus stimulate further reflection on the origin of them.
„Rozumný“ prístup k jazykovej kultúre
Authors: Dolník Juraj
Published: October 2024

The content of the paper is based on reactions that are stimulated by Alexandr Stich’s ideas in his study on the concept of language culture and its content. In his statements there is a hidden conviction about the need for a “reasonable” approach to language culture. Although the attribute reasonable in this context is questionable, the paper discusses the possibility of determining such an approach. The author’s conception is based on the conviction that the natural meaning of our behaviour and actions consists in cultivating a way of life that corresponds to our humanizing determination in the evolutionary process. From this follows the thesis that a reasonable way of human life is governed by the authority of its natural basis. This also applies to the way of cultivating the language. Language users show this by tending to linguistic behaviour that corresponds to the nature of their native language. If the democratization of a literary language has reached such a degree that its users accept it as a mother tongue, it is reasonable to cultivate it in accordance with its natural basis. The task of linguistic theory is to analyze this basis and draw “reasonable” conclusions for the approach to literary language cultivation. The attribute “reasonable” means that this approach is generally accepted in a community that is guided by the principle of rationality alone.
BAFF from Bone Marrow-Derived Mesenchymal Stromal Cells of Rheumatoid Arthritis Patients Improves Their B-Cell Viability-Supporting Properties
Authors: Dallos Tomáš , Krivošíková M. , Chorązy-Massalska M. , Warnawin E. , Záňová E. , Rudnicka W. , Radzikowska A. , Maśliński W.
Published: October 2024

Mesenchymal stromal cells (MSCs) represent a unique cell type with anti-proliferative effects on activated T and B cells. Based on our observation of differences between rheumatoid arthritis and osteoarthritis bone marrow B cells we hypothesized that rheumatoid arthritis bone marrow MSCs may enhance B-cell survival. We aimed to compare the effect of rheumatoid arthritis and osteoarthritis bone marrow-derived MSCs (rheumatoid arthritis MSCs, osteoarthritis MSCs) on the survival of healthy donor purified B cells. Rheumatoid arthritis and osteoarthritis MSCs were isolated from patients undergoing hip replacement surgery, and cultured in vitro for 2–5 passages. Washed cells were co-cultured with CD20+ B cells for 30-90 hours. Cell survival was analysed using 7-amino-actinomycin D labelling by flow cytometry. Expression of mRNA and protein was determined by RT-PCR and flow cytomery. Co-culture with both rheumatoid arthritis MSCs and osteoarthritis MSCs significantly enhanced B-cell survival, the effect being more prominent in rheumatoid arthritis MSCs. Both types of MSCs displayed expression of B cell-activating factor mRNA and protein. Blocking B cell-activating factor signalling from MSCs by specific anti-B cell-activating factor and anti-B cell-activating factor receptor antibodies weakly reversed the effect of MSCs on B-cell survival mainly in rheumatoid arthritis MSCs. MSC interaction with B cells provides stimuli for B-cell survival and therefore may contribute to the pathogenesis of rheumatoid arthritis. MSC-derived factors other than B cell-activating factor are likely to contribute to this effect. This feature is more prominent in rheumatoid arthritis MSCs, possibly due to the B cell-activating factor.
Regaining focus: Promoting attentional literacy in digital higher education
Authors: Palalas Agnieszka , Pegrum Mark , Dell Debra
Published: October 2024

The attentional demands placed on digital learners have grown, with online and blended education increasingly impacted by hyperconnectivity and digital disarray. In this context, it is essential for educators to help learners develop attentional literacy (AL). Building on past research on AL which fused insights from the fields of digital literacies and contemplative pedagogy (CP), this Delphi study examined the concept of AL and associated practices in higher education. Starting with a working definition of AL, expert feedback was invited from a global panel of experienced CP practitioners across academic disciplines. Through three Delphi rounds, the AL definition was validated and refined, before an abbreviated version was produced to facilitate operationalisation by digital educators who may not have a CP background. The study further explored how AL can be integrated into online higher education curricula, identifying strategies for educators and students to develop AL practices and address barriers to these practices. Despite systemic and structural constraints, cultivating AL allows educators and students to exercise a greater degree of individual and collective agency over their own attention in a digital world.
 
Implications for practice or policy:

Students can be guided in developing AL through a series of stages involving awareness and noticing, focus and intentional choice, openness and curiosity, and consideration of the wider attentional ecosystem.
Educators should develop their own AL first, approaching it holistically by integrating personal, pedagogical and professional development-related practices, along with complementary offline activities.
Institutions can maximise scope for AL development by increasing technological support and, especially, reducing curricular time pressure on educators and students.
Boundedness and long-time behavior in a parabolic-elliptic system arising from biological transport networks
Authors: Li Bin
Published: October 2024

The aim of this article is to consider a three-dimensional Cauchy problem for the parabolic-elliptic system arising from biological transport networks. For such problem, we first establish the global existence, uniqueness, and uniform boundedness of the strong solution by estimating the derivative of the diagonal permeability tensor with respect to time variable. Moreover, for the diffusion coefficient appropriately large, we demonstrate that the corresponding stationary problem admits a strong solution and that the solution of the Cauchy problem will stabilize to its stationary counterpart in infinite time with a time-decay rate.
Prenatal diagnosis of fetal neurogenic megacystis associated with lethal congenital contractural syndrome 2
Authors: Hatjis Christos G. , Sturtz Wendy J. , Taylor Jillian , Melchionna Elizabeth , Brown Kerry K.
Published: October 2024

Objectives

To describe the prenatal diagnosis, unique clinical features, clinical and genetic evaluation, and the pregnancy and neonatal course of two siblings affected by Lethal Congenital Contractural Syndrome 2 (LCCS2).

Case presentation

We present two cases of LCCS2, a rare autosomal recessive disorder in the arthrogryposis multiplex spectrum of syndromes whose sine qua non feature is the presence of nonobstructive, neurogenic megacystis. The prenatal diagnosis of this syndrome has not been previously reported. This syndrome has been previously studied in detail in an Israeli-Bedouin kindred but it has not been reported in the Americas.

Conclusions

These two cases illustrate the diagnostic and therapeutic dilemmas associated with this rare genetic abnormality. LCCS2 can be seen in other patient populations besides Israeli-Bedouin. They also suggest the presence of phenotypic variability in the clinical outcomes. Finally, they underscore the need for specialized diagnostic capabilities, the involvement of multidisciplinary teams to support challenging family situations, and the need for shared decision-making.
Poslovna uspješnost nakladničke industrije u Hrvatskoj, SAD i EU
Authors: Papić Anita , Sajter Domagoj
Published: October 2024

The main purpose of this paper is to provide an overview of the financial ‘health’ of the Croatian publishing market in the five-year period (2010-2015) considering the continental (EU) as well as the global context (USA) in regard to phenomenon called ‘cannibalization’. The statistical analysis of losses in revenue incurred on printed books, periodicals and newspapers and gains in revenue acquired on online and other media books, periodicals and newspapers in the US publishing industry in the five-year period (2010-2015) was conducted. The results indicate that the proliferation of alternative types of publishing revenuesin the US does not substitute (‘cannibalize’) for the evident decline of revenues incurred from the decrease in sales of printed books, periodicals and newspapers. Accumulated losses from printed items in the five-year period (2010 - 2015) aremore than three times larger than the growth in the new sector.
Canonical Correlations on Positive and Negative Attitudes of Computer-Based Statistics among Business Students
Authors: Effiyanti Tri , Sagala Gaffar Hafiz , Sukirno  , Retnawati Heri
Published: October 2024

This study aims to investigate the canonical relationship between positive and negative attitudes of economics and business students when using computer-based analytical tools. The subjects of this study were students of the Faculty of Economics and Business in Medan. Samples were taken from two universities, including state universities and private universities. Using a random sampling technique, this study collected 247 responses, consisting of 47 male and 200 female respondents. The data in this study were collected using a questionnaire with a 5-Likert scale and analyzed by canonical correlation. The results of the canonical correlation analysis in this study revealed that Perceived Usefulness (PU) and Perceive Enjoyment (PE) were critical predictors of the construct set of positive attitudes. At the same time, Strain (ST) and Negative Affectivity (NA) were essential predictors of the formation of negative attitudes among users when using computer-based statistical tools. This study produces a new insight related to attitude toward Information Technology (IT) in a specific task, namely statistical analysis. This study also has practical recommendations for universities and lecturers to invest in and use statistical software that is easy and convenient for teaching statistics.
Training in Management of BUMDes “Sumber Rejeki” Institution in Kalikayen Village, Ungaran Timur, Semarang District
Authors: Nihayah Dyah Maya , Marpaung Grace Natalia , Kistanti Nurjannah Rahayu , Setiawan Avi Budi , Setiaji Bambang , Andike Savira Ariesta Putri , Juliani Riska
Published: October 2024

Pengabdian masyarakat merupakan kegiatan untuk menerapkan ilmu sebagai bekal untuk menjawab permasalahan yang ada di masyarakat. Pengabdian masyarakat juga upaya untuk membina masyarakat untuk menemukan solusi dan inovasi. Desa yang dapat mengoptimalkan dana desa dan meningkatkan pendapatan asli desa adalah bentuk realisasi dari kemandirian desa. Untuk mencapai kemandirian tersebut, perlu adanya pengelolaan kelembagaan yang baik, pemberdayaan masyarakat, dan pengelolaan potensi desa yang efektif dan efisien.
Pengelolaan Keuangan merupakan hal penting di suatu instansi atau badan. Melalui pengelolaan keuangan dapat melihat efisiensi input-output suatu program, dan menjadi evaluasi. Pengelolaan keuangan dibagi menjadi tiga yaitu pengelolaan jangka pendek, jangka menengah, dan jangka panjang. Untuk mencapai tujuan jangka panjang, suatu badan usaha tidak dapat memisahkan antara satu dan yang lainnya karena saling berkesinambungan.
Metode yang digunakan dalam pengabdian pelatihan pengelolaan kelembagaan BUMDES Sumber Rezeki Desa Kalikayen adalah pendekatan aksi yaitu pemberian pelatihan administrasi pengelolaan keuangan. Pelatihan dilakukan dengan memberi pembimbingan pengelolaan cashflow jangka panjang. Pelatihan ini dianggap sangat penting mengingat kelembagaan yang dikelola secara optimal dapat berdampak bagi masyarakat sekitar, serta dapat mencapai tujuan dari didirikannya BUMDES. Dari metode pelatihan dan FGD diharapkan masyarakat dan aparatur desa dapat berpartisipasi untuk meningkatkan kinerja kelembagaan BUMDES.
 
Kata Kunci: Pengelolaan, Kelembagaan, administrasi, BUMDES, Sumber Rejeki
Achieving the Main Goal of Sustainable Development by Enhancing the Green Entrepreneurship Spirit Through Community Development Study Center
Authors: Pitaloka Lola Kurnia , Feriady Muhammad
Published: October 2024

Community service aims to increase students' insight and skills, and the Kendal Center for Community Development Studies tutors on green entrepreneurship. Green Entrepreneurship answers today's new business challenges. Sustainable development and a green economy demand many things to change by building something and thinking about environmental sustainability. Service activities are carried out offline using lecture methods, discussions, and the introduction of green entrepreneurship techniques. The results obtained from the service are that participants are interested in learning more about the characteristics of green entrepreneurship and are ready to enter a new era for business that supports sustainable development and understands environmental problems. The student's readiness is proven by creating new concepts to improve old business concepts to making marketing techniques that are more environmentally friendly.
Pengabdian kepada masyarakat memiliki tujuan untuk meningkatkan wawasan serta keterampilan siswa dan tentor Pusat Studi Bina Warga Kendal tentang kewirausahaan hijau. Kewirausahaan hijau menjawab tantangan bisnis yang baru saat ini. Pembangunan keberlanjutan dan ekonomi hijau menuntut banyak hal untuk berubah dengan membangun sesuatu juga untuk memikirkan keberlangsungan lingkungan. Kegiatan pengabdian dilakukan secara luring dengan metode ceramah, diskusi, serta pengenalan teknik kewirausahaan hijau. Hasil yang didapat dari pengabdian adalah peserta tertarik untuk mempelajari karakteristik kewirausahaan hijau lebih dalam dan siap memasuki era baru untuk bisnis yang mendukung keberlangsungan pembangunan serta mengerti masalah lingkungan. Kesiapan para siswa dibuktikan dengan pembuatan konsep baru guna memperbaiki konsep usaha lama hingga pembuatan teknik pemasaran yang lebih ramah lingkungan.
Training In Writing of Scientific Articles Based on Item Analysis Research
Authors: Raharjo Teguh Hardi , Marimin Marimin , Azizah Naimatul
Published: October 2024

Writing scientific articles is one of the activities a teacher must carry out in the context of Continuous Professional Development and promotion. The purpose of this Community Service activity is to provide training on writing scientific articles based on item analysis research for teachers at Madrasah Tsanawiyah Tarbiyatul Banin. The main priority of the needs of partners in the school is to provide knowledge and skills to teachers in converting the results of item analysis research that teachers have carried out into scientific articles. The agreement between MTs Tarbiyatul Banin partners and the service team is to conduct training in the writing of scientific articles. The training was conducted using a workshop approach consisting of the lecture method to teach teachers about the types of scientific publications for promotion, complete scientific article frameworks, and applicable methods. It improves teacher skills in compiling scientific articles based on item analysis research and assignments and assists in preparing scientific articles worthy of publication in national scientific journals. The results of this community service show that teachers who participate in the training are satisfied and motivated to compile scientific articles.
Penyusunan artikel ilmiah merupakan salah satu kegiatan yang wajib dilakukan oleh seorang guru dalam rangka Pengembangan Keprofesian Berkelanjutan dan untuk kenaikan pangkat. Tujuan kegiatan Pengabdian kepada Masyarakat ini adalah memberikan pelatihan tentang penyusunan artikel ilmiah berbasis penelitian analisis butir soal pada guru di Madrasah Tsanawiyah Tarbiyatul Banin. Prioritas utama dari kebutuhan mitra di sekolah tersebut adalah memberikan pengetahuan dan keterampilan kepada guru dalam mengubah hasil penelitian analisis butir soal yang sudah dilakukan oleh guru ke dalam bentuk artikel ilmiah. Kesepakatan antara mitra MTs Tarbiyatul Banin dan tim pengabdian adalah melakukan pelatihan penyusunan artikel ilmiah. Pelatihan dilakukan menggunakan pendekatan workshop yang terdiri dari metode ceramah untuk memberikan pengetahuan kepada guru mengenai jenis-jenis publikasi ilmiah untuk kenaikan pangkat, kerangka artikel ilmiah secara lengkap, metode aplikatif untuk meningkatkan keterampilan guru dalam menyusun artikel ilmiah berbasis penelitian analisis butir soal, serta penugasan dan pendampingan penyusunan artikel ilmiah yang layak publikasi di jurnal ilmiah nasional. Hasil dari pengabdian masyarakat ini menunjukkan bahwa guru yang mengikuti pelatihan merasa puas dan termotivasi dalam menyusun artikel ilmiah.