bluuebunny/crossref_metadata_2025 huggingface dataset:
Percepción del clima social laboral y de la eficiencia personal en profesionales de la salud del sector público de la ciudad de Lima
Authors: Bulnes Bedón Mario , Ponce Díaz Carlos , Huerta Rosales Rosa , Elizalde B. Roger , Santivañez Olulo Willy , Delgado Coz Eliana , Alvarez Taco Leni
Published: September 2017

OBJETIVOS: Precisar la interacción entre la Percepción del Clima Social Laboral y la Percepción de la eficiencia personal en los profesionales de la salud. DISEÑO: Es descriptivo, comparativo y correlacional, de carácter analítico en la cual se trató de determinar la prevalencia y distribución de desgaste profesional en los profesionales de la salud. MATERIAL Y MÉTODOS: Está conformada por 93 profesionales de la salud de centros hospitalarios públicos entre médicos, enfermeras, obstetrices, psicólogos, trabajadores sociales y tecnólogos médicos. Para la evaluación de las variables se utilizaron La Escala de Clima Social Laboral elaborado por Rudolf Moos y Bernice Moos, y el Inventario de Burnout elaborado por Cristina Maslach y Susan Jackson.
Índice percibido de la calidad ambiental y estrés ambiental en estudiantes de la UNMSM
Authors: Hernández Valz Héctor M. , Rivera Benavides José C. , Paredes Tarazona Mildred T.
Published: September 2017

OBJETIVO: Relacionar el índice percibido de la calidad ambiental con el estrés ambiental en estudiantes de la UNMSM - Perú. DISEÑO: Descriptivo correlacional con una muestra intencional de 200 sujetos. MATERIAL Y MÉTODOS: Se usó el diferencial semántico para medir ambas variables. Se midieron 5 aspectos del ambiente seleccionados por la muestra: la basura, áreas verdes, el smog, el tránsito, la seguridad, siendo el SMOG considerado el más grave. RESULTADOS: Se encontró un índice PEQI igual a 3,82, ligeramente satisfactorio. El nivel de estrés ambiental medido fue de una media de 3,45, poco satisfactorio. CONCLUSIONES: Ambos resultados indican una relación poco buena con el entorno. La relación entre ambas variables tiene una r igual a 0,62, es decir que es significativa.
Editorial
Authors: Orellana Manrique Oswaldo
Published: September 2017

El año 2005 será recordado por la celebración de los cincuenta años de psicología en San Marcos y en el Perú. Medio siglo que merece ser evaluado por la presencia de la ciencia psicológica, en un país complejo y contradictorio. Nuevos desafíos al espíritu universitario y renovador se presentan hoy, evaluar el papel histórico de la universidad y el papel de la psicología en desentrañar las redes que explican la condición de las individualidades en sus distintas expresiones y manifestaciones, tanto de la normalidadcomo de los estados alterados de la mente y viceversa, de los contextos sociales regulados y de los desequilibrios socioeconómicos funcionales, como expresiones de las crisis de descomposición que en ciertos momentos de la historia se presentan, y que en algún momento hay que afrontar académica y profesionalmente, y aunque su solución probablemente no se encuentre en la Psicología, ésta nos puede brindar ciertos soportes teóricos y prácticos para comprender el fenómeno en su real dimensión.
Psicología y mestizaje: una aproximación histórica y Psicoeducativa
Authors: Orellana Manrique Oswaldo
Published: September 2017

La presente investigación se realizó en tres ambientes de socialización: costa, sierra y selva, con el objetivo de establecer las diferencias que existen en determinadas características psicológicas en jóvenes escolares que se autocalifican con un estereotipo determinado. Para la evaluación histórica se ha tomado en cuenta la producción de conocimientos de las ciencias sociales y para la evaluación psicológica una escala de actitudes hacia la vida que mide resentimiento. El producto de la investigación involucra temas de identidad y de integración social, desde una perspectiva histórica y psicológica muy importante, tanto desde el punto de vista práctico como teórico, ya que se convierte en una información valiosa para la educación y la psicología, en la comprensión de distintos grupos humanos que coexisten en el Perú. Como el tema de mestizaje no tiene antecedentes para su evaluación psicológica, y dadas las características históricas violentas en su desarrollo, se ha seleccionado la categoría resentimiento como un rasgo distinguible, formulando dos aspectos a investigar, uno histórico y otro empírico. Se encuentra que existen diferencias significativas en los escolares socializados en las tres regiones investigadas, así tenemos que los escolares de la costa obtienen menor puntaje en la escala para la vida, mientras que en la sierra prevalece un puntaje por encima de la mediana, significando ausencia de resentimiento y una socialización con menor discriminación. En la selva los resultados indican que la actitud hacia la vida es más homogénea, es decir, que no se encuentran puntajes opuestos como se da en la costa y sierra.
Editorial
Authors: Orellana Manrique Oswaldo
Published: September 2017

La función principal de la universidad es la investigación, y por lo tanto, la producción de conocimientos, sin la cual, no puede existir cultural, social e institucionalmente. Esta premisa categórica debe conducirnos hacia un conjunto de reflexiones que se inicia con la identificación del paradigma de universidad que sostiene su funcionamiento. Valorizar el perfil del docente universitario como investigador, además de enseñante, es decir especialista en trasmitir la información especializada. Reconocer el protagonismo institucional en la cultura nacional, la ciencia y la tecnología, que la ubique en un lugar privilegiado e identifique el modo de producción de conocimientos específicos que la caracteriza.
Ajuste psicosocial y estado depresivo en adolescentes de centros escolares de Lima Metropolitana
Authors: Bulnes B. Mario S. , Ponce D. Carlos R. , Huerta R. Rosa E. , Elizalde B. Roger , Santivañez O. Willy R. , Aliaga T. Jaime R. , Alvarez T. Leni , Calmet A. Roberto F.
Published: September 2017

A partir de la preocupación por el aumento de la frecuencia de depresión y la disminución de la edad de las personas que padecen este tipo de problema, así como algunos indicadores que lo acompañan y que se encuentra dentro del concepto de desajuste psicosocial, surge la necesidad de estudiar dichos fenómenos en la población escolar. Objetivos: Demostrar la relación interdependiente de las variables ajuste psicosocial y depresión en escolares del nivel secundario de Lima Metropolitana, en función al tipo de colegio (estatal y particular) y género. Diseño: Es una investigación de tipo básica y de diseño descriptivo comparativo y correlacional. Material y método: La muestra estuvo constituida por 480 escolares de centros educativos estatales y particulares, cuyas edades oscilan entre los 12 y 17 años. Para la evaluación de la variable ajuste psicosocial, se utilizó el Inventario de Adaptación de Conducta de M. Victoria de la Cruz y Agustín Cordero, y para evaluar la variable depresión, se utilizó el Cuestionario de Depresión para niños y adolescentes de M. Lang y M. Tisher. El análisis estadístico derivó en primer lugar, en un análisis de validez y confiabilidad de las pruebas, y en segundo lugar, se realizó un análisis inferencial para la contrastación de las hipótesis planteadas. Resultados: Se ha encontrado que las dos pruebas utilizadas son altamente válidas y confiables.
El síndrome del "quemado" por estrés laboral asistencial en grupos de docentes universitarios
Authors: Ponce Díaz Carlos R. , Bulnes Bedón Mario Santiago , Aliaga Tovar Jaime Ramiro , Atalaya Pisco María Clotilde , Huerta Rosales Rosa Elena
Published: September 2017

Objetvos: Conocer la posible presencia del síndrome del "quemado" por estrés laboral asistencial en grupos de docentes de una Universidad Nacional, pertenecientes a diversas áreas de especialidad. Describir posibles diferencias significativas en el síndrome del "quemado" por estrés laboral asistencial, según áreas de especialidad y en relación a las variables Sexo, Estado Civil, Práctica de Deporte, Problemas de salud y Condición docente. Diseño: Es descriptivo, comparativo y correlacional, de carácter analítico, realizado en profesores universitarios distribuidos en cinco áreas de especialidad en el cual se trato de detectar la presencia e implicancias del síndrome del "Burnout".
El enfoque multimodal y las escuelas de Psicoterapia
Authors: Kertész Roberto
Published: September 2017

Se realiza una reseña de la terapia multimodal creado por Arnold Lazarus, describiendo el estado integrativo presente de una persona, a partir de los siete modales o variables de la personalidad total: Biológico, afectivo, sensaciones, imágenes, cognitivo, donductas y social. Expone el perfil multimodal como un instrumento que discrimina lo único, lo irrepetible de cada individuo. Finalmente distingue el eclecticismo teórico y el eclecticismo técnico, valorizando el aporte de otros enfoques.
Una alternativa para incentivar y crear lugares de acogida
Authors: Alcarazo V. Yober P.
Published: September 2017

Este es un artículo que nos permite reflexionar sobre la importancia que nos brindan los lugares y espacios de acogida en las familias de bajos recursos económicos. Creo, por mi experiencia de interno en La Casa de la Familia, al darles la posibilidad de "alimentarse" de forma distinta, mediante la palabra, el juego, con una escucha atenta, respetuosa, nuestra acogida y el vínculo, las familias puedan superar sus propias dificultades psicológicas.
La orientación vocacional en los colegios públicos y privados de Lima: situación actual y propuesta de un programa de acción para la secundaria pública
Authors: Frisancho León Augusto Emilio
Published: September 2017

El objetivo principal del presente estudio fue determinar si existían o no diferencias en la forma de llevar a cabo la orientación vocacional de sus estudiantes entre los colegios públicos y privados de Lima Metropolitana. Aplicando un cuestionario a una muestra de 279 alumnos –entre hombres y mujeres– que acababan de terminar su educación secundaria y que se encontraban realizando estudios preuniversitarios, se llegó a establecer que sí hay diferencias: la orientación vocacional que reciben los alumnos en los colegios públicos es más pobre (contempla menos aspectos) y se lleva a cabo de manera casi puntual (sólo en 5to. o, a lo más, en 4to. y 5to. de secundaria) que la recibida por los alumnos de los colegios privados. Además, los alumnos de los colegios públicos califican mayormente de «regular» la orientación vocacional recibida, mientras que los alumnos de los colegios privados la califican principalmente de «buena». Adicionalmente a estos resultados, el presente estudio plantea un programa de orientación vocacional para ser realizado con los estudiantes de los colegios públicos, programa que busca ser integral y llevarse a cabo a lo largo de los tres últimos años de la secundaria.
La investigación cualitativa (síntesis conceptual)
Authors: Martínez M. Miguel
Published: September 2017

El Documento nos brinda un panorama amplio de la investigación cualitativa. Inicia con una revisión necesaria del tema del conocimiento, abordado desde su naturaleza epistemológica para poder entender la totalidad concreta de la realidad, y en la terminología del autor, como un todo polisistémico y la interdisciplinariedad. En un segundo plano identifica la dimensión dinámica de la investigación cualitativa, en cuanto trata de identificar la naturaleza profunda de las realidades, su estructura y relaciones que se establecen, para cumplir las dos tareas básicas de toda investigación: recoger datos y categorizarlos e interpretarlos. Hace un tratamiento del marco referencial, los objetivos, las hipótesis y las variables, identificando varios métodos cualitativos, así como los instrumentos y procedimientos.
Análisis psicolingüístico del desarrollo fonéticofonológico de alumnos preescolares de Lima Metropolitana
Authors: Dioses Ch. Alejandro S. , García A. Lupe , Matalinares C. María , Cuzcano Z. Abel , Panca Ch. Noemí , Quiroz W. Janet , Fernández R. Carla , Castillo R. Jenny
Published: September 2017

Siguiéndose el planteamiento de las reglas fonológicas, se realizó un estudio descriptivo del desarrollo fonético-fonológico de alumnos preescolares de Lima Metropolitana seleccionados mediante un muestreo aleatorio estratificado. La recolección de la información se efectuó con el Test de Desarrollo Fonético-Fonológico conformado por dos áreas: conciencia fonológica y reglas fonológicas, evaluándose fonemas consonánticos y vocálicos de la lengua española. Los resultados mostraron que existían diferencias significativas en el uso de la conciencia fonológica de rima y aliteración, según el nivel socioeconómico; sin embargo, las diferencias eran no significativas al considerarse las variables de sexo y edad. También se encontraron diferencias no significativas en el uso de las reglas fonológicas en función del sexo, edad y nivel socioeconómico.
Estudio psicológico sobre los patrones de conducta en contextos de tráfico, en grupos de automovilistas particulares y profesionales de Lima Metropolitana
Authors: Ponce D. Carlos , Bulnes B. Mario , Aliaga T. Jaime , Delgado C. Eliana , Solís N. Rolando
Published: September 2017

Objetivos: 1. Conocer los estilos de comportamiento en contextos de tráfico que presentan los automovilistas de servicio público y los choferes particulares de Lima Metropolitana. 2. Detectar la existencia de diferencias significativas en los estilos de conducta en contextos de tráfico, entre los choferes de servicio público y los automovilistas particulares de Lima Metropolitana, de manera global y específica. 3. Investigar la existencia de diferencias significativas en los estilos de conducta en contextos de tráfico entre los conductores de servicio público y los choferes particulares de Lima Metropolitana, en relación a las variables: edad cronológica; estado civil; grado de instrucción; lugar de procedencia; pertenencia del vehículo; la conducción como ocupación principal; tiempo en la conducción; accidentes de tránsito; papeletas recibidas por infracciones; problemas de salud; problemas auditivos; problemas de motricidad; problemas familiares y problemas emocionales. 4. Estudiar la confiabilidad y validez del cuestionario PSS que evalúa patrones de conducta de los automovilistas en contextos de tráfico.
Percepción, tipos y medidas de control de la corrupción, según el sexo, ciclo académico y la facultad a la que pertenecen los estudiantes universitarios
Authors: Vicuña P. Luis , Hernández V. Héctor , Paredes T. Mildred , Rivera B. José C. , Ríos D. José , Santillana P. Christian , Torres M. Jenny
Published: September 2017

El presente estudio trata de la forma como el universitario conceptúa a la corrupción, identifica actos corruptos dentro de su facultad y proponen soluciones, en función al sexo, ciclo y facultad académica a la que pertenecen. La muestra fue de 931 representativa al 0,03 de margen de error, distribuidos por facultades académicas. La muestra seleccionada aleatoriamente contestó a un cuestionario de tres preguntas, previamente validadas semánticamente; luego en grupos no mayores de diez estudiantes se conversó acerca de sus respuesta con el objeto de conocer la confiabilidad de las mismas, encontrando una correlación del 0,90 entre las opiniones profundizadas en la sesión dinámica con sus respuestas escritas en el cuestionario. Sobresalen resultados, respecto a la conceptualización de la corrupción: el 8% dicen que es transgresión de normas, 11% abuso de autoridad, 15% como un delito, para el 9% es una enfermedad, para el 37% benefico personal. Entre los actos corruptos percibidos atribuyen al abuso de poder de la burocracia el 33%, 9% a enriquecimiento ilícito y a alumnos que pagan coimas respectivamente, 8% abuso de poder del docente. En las soluciones para controlar la corrupción proponen: el 19% educación en valores, 13% fiscalizando, 8% transparencia, cambio de sistema, cambio individual y concientización, respectivamente, 7% aplicación de medidas restrictivas. Estos datos no difieren en función al sexo ni al ciclo ni a la facultad académica a la que pertenecen.
THE INFLUENCE OF OCCLUSAL STABILIZATION APPLIANCES ON CERVICAL DYSTONIA SYMPTOMS
Authors: Navrotchi Camelia , Badea Mîndra Eugenia
Published: September 2017

Objectives. The aim of this study was to assess the therapeutic efficiency of the occlusal stabilization appliance (OSA) in patients with cervical dystonia (CD).Methods. The study included 11 patients aged between 29 and 80 years, 7 women and 4 men, diagnosed with primary CD. The patients underwent an extra- and intra-oral clinical examination, followed by para-clinical examinations, necessary for the specifications of the OSA. The following data were recorded: demographic parameters, CD duration, management of the disease, dental impression, recording of the centric relationship, recording of the position of the upper jaw with the facial bow. A standardized OSA was manufactured in a private dental laboratory. Patients received instructions for wearing the OSA for 24 hours. Patients filled a questionnaire designed by us, which evaluated the effects of wearing the OSA over a 24-hours period on the symptoms of CD: muscles contraction, pain, discomfort while walking, sleep quality, tremor. The patients kept the dental appliances, and after three months they completed the questionnaire one more time. Results. The OSA was applied on the lower arch in 3 (27.3%) patients and on the upper arch in 8 (72.7%) patients. The OSA wearing time for the first 24 h was on average 19.2±6 hours. Total relaxation of dystonic muscles was reported by 9 (81.8%) patients, while 2 (18.2%) patients related partial muscle relaxation. Seven (63.6%) patients reported a pain decrease. Increased comfort while walking was observed by 8 (72.7%) patients. Two (18.2%) patients described an increase of sleep quality. In two (18.2%) patients the tremor disappeared. All patients reported difficulties while eating and removed the OSA during meals. Patients who wore the OSA for more hours, experienced a pain decrease (p=0.08), an increase in sleep quality (p=0.1), the disappearance of the tremor (p=0.1). After three months, only seven patients continued to use the OSA. More patients described a pain decrease after three months (5 (71.4%) vs. 4 (57.1%); p=0.5), relaxation of dystonic muscles (7 (100%) vs. 6 (85.7%); p=0.3). Conclusions. The use of OSA might be beneficial in CD patients, as it reduced the dystonic symptoms, pain severity and improved the quality of sleep.
Cholangiocarcinoma in Wilson’s Disease – a Case Report
Authors: Németh Dániel , Folhoffer Anikó , Smuk Gábor , Kajtár Béla , Tornóczky Tamás , Szalay Ferenc
Published: September 2017

It has been suggested that hepatobiliary carcinomas are less frequent in Wilson’s disease (WD) than in liver diseases of other etiology. However, the protective role of copper against malignancies is debated. Only a few cases of cholangiocarcinoma (CCC) in WD have been published. Here we report on a case of a 47-year-old male H1069Q homozygous, Kayser-Fleischer ring positive WD patient with a low ceruloplasmin level who was followed up and treated with chelating agents throughout nine years. The patient presented with neurological symptoms and liver cirrhosis at diagnosis. Clinical symptoms regressed after the treatment initiation. Rapidly developed tumour metastases were found in the bones, lung and liver (without jaundice). Autopsy revealed cholangiocarcinoma as the primary tumour confirmed by strong CK7 positivity and glypican-3 negativity. The curiosity of the presented case is the very rapid development of CCC despite continuous chelating agent therapy.Abbreviations: CCC: cholangiocarcinoma; HCC: hepatocellular carcinoma; WD: Wilson disease.
Serum Concentrations of Th17-Associated Interleukins and Autoimmune Phenomena are Associated with the Degree of Liver Damage in Alcoholic Liver Disease
Authors: Kowerda Anna Parfieniuk , Swidersk Magdalena , Szulzyk Tomasz , Jaroszewicz Jerzy , Lapinski Tadeusz W. , Flisiak Robert
Published: September 2017

Background & Aims: Recent reports suggest an involvement of Th17 responses in inflammatory and autoimmune reactions in alcoholic liver disease (ALD). Our study aimed to assess serum levels of Th17-interleukins in ALD with regard to the frequency of liver-specific autoantibodies and degree of liver damage.Methods: Ninety-five patients with ALD were enrolled. Serum concentrations of IL-17F, IL-17A, IL-22 were assessed by ELISA. The presence of autoantibodies AMA-M2, SLA/LP, LKM-1, LC1, anti-F-actin, anti-desmin and anti-myosin in serum was assessed by immunoblotting, ANA antibodies were detected by ELISA. The results were analysed with regard to the degree of hepatic damage.Results: Serum IL-17F was significantly elevated in ALD patients compared to controls (p=0.03). There was a correlation between serum IL-17F and degree of liver failure evaluated by the MELD score (rs=0.23, p=0.03). Serum IL-22 also correlated with MELD score (rs=0.32, p=0.007) and CTP score (rs=0.28, p=0.02). Anti-F-actin antibodies were present in 19% and ANA-antibodies in 11% of the patients in the study group, and in no subjects in the control group. The prevalence of anti-F-actin autoantibodies was higher in subjects with more advanced liver diseases but also independently associated with IL-17A in the regression analysis. Furthermore, serum IL-22 in anti-F-actin(+)-patients was significantly higher compared to anti-F-actin(-)-patients (p=0.03).Conclusions: Elevation of serum IL-17A, IL-17F, IL-22 correlated with the progression of liver damage and also with presence of F-actin in ALD. Alcoholic liver disease may trigger autoimmunity and formation of autoantibodies, especially anti-F-actin, with possible engagement of Th17-related cytokines in this process.Abbreviations: AA: acetaldehyde; Abs: antibodies; AFP: α-fetoprotein; ALD: alcoholic liver disease; ALT: alanine aminotransferase; AMA-M2: antimitochondrial antibodies; ANA: antinuclear antibodies; ASMA: anti-smooth muscle antibodies; α-SMA: alpha smooth muscle actin; CTP Score: Child-Turcotte-Pugh Score; GAHS: Glasgow Alcoholic Hepatitis Score; GGT: γ-glutamyl transpeptidase; HBV: hepatitis B virus; HCV: hepatitis C virus; HIV: human immunodeficiency virus; HSCs: hepatic stellate cells; IL-β1: interleukin β1; IL-6: interleukin 6; IL-17A: interleukin 17A; IL-17F: interleukin 17F; IL-22: interleukin 22; KCs: Kupffer cells; LC1: liver cytosol antigen type 1; LKM-1: liver kidney microsomal antigen; MA: malondialdehyde; MELD: Model of End-Stage Liver Disease; NASH: non-alcoholic steatoheptatitis; SLA/LP: soluble liver antigen/liver-pancreas; TGF-β: tumour growth factor β; TNF-α: tumour necrosis factor α.
Position Paper on Treatment of Hepatitis C in Romania 2017. Part Two
Authors: Gheorghe Liana , Sporea Ioan , Iacob Speranța , Șirli Roxana , Trifan Anca , Diculescu Mircea , Stanciu Carol , Pascu Oliviu , Acalovschi Monica , Brisc Ciprian , Cijevschi Cristina , Gheorghe Cristian , Spârchez Zeno , Rogoveanu Ion , Dobru Daniela , Dumitrascu Dan L.
Published: September 2017

Background & Aims: Hepatitis C virus (HCV) infection is a common condition with endemic prevalence in some areas of the world. In Romania, the mean prevalence is about 3%. New treatments have become available on the market in recent years and new drugs are in the pipeline. A re-evaluation of HCV therapy was considered mandatory. The Romanian Society of Gastroenterology and Hepatology undertook this task for the practitioners of this country.Methodology: A group of recognized experts was created who screened the available literature and the major available guidelines. A list of items requiring attention was created and these were discussed and rated. Decisions were taken by consensus.Recommendations: We present here the second part of the Society’s recommendations for chronic HCV infection treatment. An agreement between experts was reached regarding the therapy of the special categories of patients infected with HCV, complications and monitoring of the therapy, follow-up of the patients who reached sustained virologic response and re-treatment of the patients with therapy failure.Conclusions: This Position Paper represents a guide for the assessment and the therapy of HCV infection. The recommendations are in concordance with other guidelines but are applied to real-life conditions in Romania. Abbreviations: CKD: Chronic kidney disease; DAAs: Direct-acting antivirals; DDIs: Drug-drug interactions; ESDL: End-stage liver disease; FCH: Fibrosing cholestatic hepatitis; GT: Genotype; HCV: Hepatitis C virus; HCC: Hepatocellular carcinoma; LT: Liver transplantation; MELD score: Mayo-Clinic End-Stage Liver Disease score; PDC: Premature discontinuation; PWID: Persons who inject drugs; RASs: Resistance associated substitutions; RBV: Ribavirin; RCT: Randomized controlled trial; SAE: Serious adverse events; SRGH: Romanian Society of Gastroenterology and Hepatology; SVR: Sustained virologic response.
Caracterización de las problemáticas de la cadena de abastecimiento
Authors: García Cáceres Rafael Guillermo , Escobar John Wilmer
Published: September 2017

El trabajo identifica 123 problemáticas cada una de las cuales es vinculada en la estructura mediante una notación. Para ilustrar el desarrollo de trabajos futuros se usa como ejemplo de caracterización el problema de programación de la producción. La estructura aquí definida establece una base que facilita el despliegue teórico de nuevos desarrollos en gerencia de la cadena de abastecimiento y a su vez facilita la labor de los tomadores de decisión. El trabajo representa un esfuerzo por establecer una visión holística para el estudio de la cadena y su mejoramiento en términos de competitividad y sostenibilidad en pro del beneficio de sus stakeholders.
Editorial
Authors: Moreira Maria Eunice , Chaves Vania Pinheiro
Published: September 2017

---
High prevalence of OXA-type carbapenemases among Acinetobacter baumannii strains in a teaching hospital of Tehran
Authors: Zafari Mandana , Feizabadi Mohamad Mehdi , Jafari Sirous , Abdollahi Alireza , Sabokbar Azar
Published: September 2017

Nosocomial infection caused by carbapenem-resistant Acinetobacter baumannii (CRAB) has created a public health concern all around the world. In this study, 100 isolates of CRAB from hospitalized patients during 2015–2016 at Imam Khomeini Hospital were investigated to determine the rates of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains using Kirby–Bauer disk diffusion method. The minimum inhibitory concentrations (MICs) of six antibiotics were determined by broth microdilution method. Multiplex polymerase chain reaction (PCR) was performed to detect blaOXA-51 like and blaOXA-58 like, blaOXA-23 like, and blaOXA-24 like that are encoding resistance to carbapenems. All CRAB isolates were MDR and XDR and 2% of them were pandrug-resistant (PDR), whereas colistin, polymyxin B, and tigecycline were the most effective agents. All isolates were positive for blaOXA-51 like by PCR. The frequency of blaOXA-23 like and blaOXA-24 like was 81% and 22%, respectively. Findings of this study showed that very few therapeutic options remained for the treatment of CRAB infections and blaOXA-23 like is a dominant resistance gene in CRAB at this hospital.
Korai petefészek-kimerüléssel összefüggő tünetek bio-pszicho-szociális szemléletű kezelése
Authors: Szigeti F. Judit , Ács Nándor
Published: September 2017

Abstract:

The basic legal conditions for pursuing medical activities in Hungary require that psychologists be employed at certain somatic departments. In the Hungarian medical practice, however, attitudes recognizing the potential role of psychological factors in the course of diseases are not widely present. The modern psychosomatic approach to healing includes biological, psychological and social factors that may predispose one to, precipitate or perpetuate a medical condition. This case study of a 35-year-old woman reports on a therapy in which the symptoms were indicative of both premature ovarian failure and anxiety, influencing each other in a bidirectional way. Therapy also included interventions on physical (hormonal therapy, Jacobson’s progressive relaxation technique) and psychological levels (cognitive behavioral interventions). This case management is an example for how physician-psychologist collaboration serves the best interests of patients. Orv Hetil. 2017; 158(36): 1432–1435.
BETEL LEAF EXTRACTS (PIPER BETLE L.) PREVENT ENDOTHELIAL DYSFUNCTION BY REDUCING THE LEVELS OF URIC ACID AND ICAM-1 EXPRESSION OF THE HYPERURICEMIA WISTAR RATS (RATTUS NORVEGICUS) AORTIC ENDOTHELIAL
Authors: Sumarya Made , Adiputra Nyoman , Manuaba Putra , Sukrama Dewa
Published: September 2017

Hyperuricemia as a risk factor for cardiovascular disease causes endothelial dysfunction by increasing oxidative stress and inflammation. Extracts of betel leaf (Piper betle L.) contain bioactivity as an antioxidant, anti-inflammatory and XO inhibitor. The aim of the research is to determine the betel leaf extracts can prevent endothelial dysfunction caused by hyperuricemia by lowering uric acid levels and the expression of ICAM-1 endothelial aorta. The experimental research was conducted by the design of The Post Test Only Randomized Control Group Dsign, performed on untreated animals and rats fed with oxonic potassium (hyperuricemia), and compared to hyperuricemic rats treated with either betel leaf extract or allopurinol. After the experiment, the blood uric acid levels and the expression of aortic endothelial ICAM-1 were determined. The research results showed that the betel leaf extract lowered significantly (p <0.05) the blood uric acid levels and the expression of ICAM-1, rat aortic endothelial hyperuricemia. There is a positive correlation between the levels of uric acid with the expression of aortic endothelial ICAM-1 (p <0.05). It can be concluded that the betel leaf extracts can prevent endothelial dysfunction caused by hyperuricemia by lowering the uric acid levels and the expression of ICAM-1 aortic endothelial.
Comparison of Microscopic to PCR for Detecting Microfilaria in 21 Lymphatic Filariasis Patients Treated with Diethylcarbamazine
Authors: Tan Suriyani , Supriyono Supriyono , Ullyartha Helena
Published: September 2017

Background: Lymphatic filariasis (LF) marked by the World Health Organization (WHO) as one of seventeen Neglected Tropical Disease (NTD) which can be eliminated. Giemsa-stained blood smear remained as the standard method to detect microfilariae, albeit this method has many weaknesses. The PCR method has long been proposed to replace it, but PCR is seldom used in a routine examination. Objective: This study aimed to examine the sensitivity and specificity of standard examination compared to PCR in post-therapy subjects. Methods: As many as 21 subjects, who had received Diethylcarbamazine (DEC) for 10 days, were enrolled in the study. The capillary blood sample was taken 6 months after the therapy. Half of the blood samples was examined using Giemsa â€“stained blood smear, and the other half using the PCR. Results: From 6 positive samples, the PCR only confirmed 4 of them. The sensitivity of the blood smear was 100% and the specificity was 88%. Conclusion: The Giemsa-stained capillary blood smear has a better sensitivity and specificity compared to the PCR. Thus, it remains the gold standard to check microfilaria in routine field examination. A PCR can be used as an alternative.
Contribution of early hyperglycemia and hypoalbuminemia to multiple organ dysfunction syndromes (mods) in multitrauma patients
Authors: HB Hendri , H Sapan , JH Lampus , L Lolombulan
Published: September 2017

Background: Recent randomized prospective data suggest that early hypoglycemia and hypoalbuminemia are associated with MODS in multitrauma patients. Objective: this study was to determine the contribution of early blood glucose elevation and decrease serum albumin in Trauma Emergency Department or ICU patients. Methods: We prospectively collected multitrauma patients with Injury Severity Score (ISS) â‰¥ 18, blood glucose, serum albumin, between 14 â€“ 81 years old, admitted to level I Trauma Centre at Kandou General Hospital Manado for eleven months periods from September 2015 until July 2016. Sequential Organ Failure Assessment (SOFA) Score was used to determine MODS during hospitalization. Results: A total of 51 multitrauma patients were included in this study. The mean age was 31.73 years old, male 41(80.4%) and female 10(19.6%). Serum glucose level> 126 mg/dl occurred in 34 (66.7%) patientsand â‰¤ 126 mg/dl occurred in 17 (33.3%) patients. Serum albumin level Ë‚ 3,5 gr/dl occurred in 31 (60.8%) patients and â‰¥ 3,5 gr/dl occurred in 20 (39.2%) patients. Conclusion: Early hyperglycemia as defined by glucose >126mg/dl and hypoalbuminemia as defined by albumin <3,5gr/dl are associated with significantly higher MODS rates in multitrauma patients independent of injury characteristics. The present of early hyperglycemia and hypoalbuminemia may allow early identification of trauma patients who are at risk for MODS.Â
Progress and potential roles blood biomarkers of ischemic stroke in clinical setting
Authors: Wiryadana Kadek Adit , Supadmanaba I Gede Putu , Samatra Dewa Putu Gde Purwa
Published: September 2017

Stroke is one of the leading causes of death and disability which involving a complex pathophysiology with multiple mechanisms. Rapid treatment is necessary to terminate the disease progression, hence minimizing CNS damage and subsequent disability. Stroke diagnostic process composed of history taking, neurological examination and supplemented with neuroimaging. Imaging modalities such as CT-scan or MRI are essential in establishing a definitive diagnosis of ischemic stroke. However, the high cost and limited number made them inaccessible for those who have low or middle income which will delay the diagnosis and treatment. On the other hand, blood biomarker has potential in either diagnostic or prognostic aspect of ischaemic stroke management. It has a promising potential to aid diagnosis, determine the subtype of stroke, predicting the outcome or early neurological deterioration, and recurrence. It also could potentially help to assess the risk of hemorrhagic transformation, treatment selection, as well as to detect salvageable ischemic penumbra. Although it could not replace neuroimaging, blood-based biomarker assessment had lower cost and faster result. However, despite its promising potential, none of the blood biomarkers is currently used in clinical practice. Therefore, further studies are needed to develop biomarkers or panels of biomarkers with better sensitivity and specificity. This review provides a highlight and summary of blood biomarkers based on their potential application in a clinical setting.
IMPROVEMENT OF CONDITIONS AND WORKING ENVIRONMENT THROUGH ERGONOMICS INTERVENTION IMPROVED PERFORMANCE AND PRODUCTS QUALITY OF DODOL WORKERS AT PENGLATAN VILLAGE BULELENG RESIDENCY
Authors: Santosa I G. , Adiputra N. , Manuaba A. , Tirtayasa K.
Published: September 2017

The success of production is largely determined by the conditions and working environment that will affect the comfort, safety and health of workers. Conditions and working environment did not ergonomic ally designed causing dodol workers in the Penglatan village Â Buleleng cannot work optimally. Thus, there should be conducted an ergonomic intervention on conditions and working environment of dodol worker by designing dodol mixer, organizational and working environment withÂ  ergonomics interventions through the application of appropiate technology and SHIP concepts approaches. This study was an experimental study with Randomized Pretest and Posttest Control Group Design. This design was a parallel design with number of sample 34 people who were divided into 2 groups they are control and experiment group. Control group that works with the original conditions and working environment totaling 17 peoples and 17 others as the treatment group that works with conditions and working environment that has been improved base on ergonomics. Data were analyzed with a significance level of 5%. The research result showed that there was a decrease in work load between the control and the experiment group 17,11%, decrease in CVL 42,14%, ECPM value was higher than that of ECPT, decrease in musculoskeletal 37,35%, and the tiredness level was34,11%. Work productivity increased from physiological aspect 67,11%, and from economic aspect 179,73%. Based on investment evaluation, NVP value in 5 years was Rp.54.414.450,-, PBP values was 0,26 years less than 5 years and RoI value 19,6% higher than bank interest rate 14%. Laboratory test result showed that there was improvement of dodol quality based on SNI requirement. It was concluded that the improvement of conditions and working environment with ergonomics interventions through the application of TTG and approach of SHIP can improve performance by decreased workload categories, decreased musculoskeletal complaints, decreased fatigue and increase the workers income levels and improve the dodol quality.
IMPACT CERVICAL CANCER AND CHEMOTERAPY TO SEXUAL LIFE IN CERVICAL CANCER PATIENT ( Case Report )
Authors: Sutiawan A. , Noviyani R. , Suwiyoga K.
Published: September 2017

Cervical cancer Â has a second place cancer disease that attacks women after breast cancer. Chemotherapy is treatment for cervical cancer. Symptoms of cervical cancer and chemotherapy can cause to decrease quality of life terms sexual life patient. We reported a case, a woman diagnosed cervical cancer stage III B complained the symptoms of cervical cancer such bleeding, pain, and leucorrhea caused to distrube her sexual life with her partner. In addition, Â the side effects of chemotherapy such as fatigue also caused to decreased sexual life in these patient.
Rehabilitation of Old Flatts Bridge, UK
Authors: Biana Ipsa
Published: September 2017

The Old Flatts Bridge in Rotherham, UK, carries the A630 Sheffield Parkway over a busy freight railway. The A630 is a key link between Rotherham, Sheffield and the M1. It is also a major arterial route into Sheffield and nearby industrial and business parks. A principal inspection of the bridge identified that the span between the abutment faces had shortened by 216 mm compared with the as-built drawings. The bearings were badly corroded and were translated well beyond their design limit, both laterally and longitudinally. The bearings were thus non-functional. The nominal movement gaps at both free and fixed ends were closed, thus ‘locking’ the structure in position. This paper describes the damage observed and the construction mechanisms that led to the failure. The paper also identifies the cause of the problem and discusses the innovative approach taken in rehabilitating the bridge. From the outset, the principal aim of the rehabilitation design was to reduce future maintenance of the structure, as the bridge is very close to a very busy motorway junction. The paper also discusses the mode of retrofitting involved in modifying the bridge’s sub- and superstructure to transform the bridge deck behaviour.
Overview of intermediate highway cross-sections
Authors: Bassan Shy
Published: September 2017

The paper presents an overview of safety and insights regarding traffic at highway intermediate cross-sections in the interurban highway network. This overview includes rigid and soft ‘one plus one’ cross-sections, passing lanes traffic and geometric characteristics, as well as criteria for widening a two-lane highway to form a divided multilane highway. The design overview of intermediate highway cross-sections includes traffic and safety warrants, design speed characteristics and cross-section infrastructure components, including elements that enhance traffic safety. These developments are partly an outcome of the new Israeli geometric design policy and controls for rural (interurban) highways.
KELAS SOIL DAERAH SEKITAR RENCANA TAPAK REAKTOR DAYA EKSPERIMENTAL (RDE) SERPONG DARI DATA MIKROTREMOR
Authors: Marjiyono Marjiyono , Suntoko Hadi , Soehaimi A. , Yuliastuti Yuliastuti , Syaeful H.
Published: September 2017

ABSTRAK KELAS SOIL DAERAH SEKITAR RENCANA TAPAK REAKTOR DAYA EKSPERIMENTAL (RDE) SERPONG DARI DATA MIKROTREMOR. Karakteristik geologi permukaan memegang peranan penting dalam analisis respon gelombang di suatu wilayah.  Sehubungan dengan rencana pembangunan Reaktor Daya Eksperimental (RDE) di Serpong, telah dilakukan pemodelan kondisi bawah permukaan dari kombinasi data mikrotremor array dan single station. Pengukuran mikrotremor array dilakukan di 9 lokasi, sedangkan single station di 90 lokasi yang tersebar pada radius ± 1 km di sekitar tapak RDE. Model bawah permukaan yang berupa struktur kecepatan gelombang geser selanjutnya dijadikan dasar untuk menghitung nilai Vs30 di daerah tersebut. Hasil klasifikasi soil berdasarkan nilai Vs30 menunjukkan kelas soil untuk wilayah sekitar tapak RDE secara umum terdiri atas kelas SD (soil menengah) dan SC (batuan lunak). Lokasi rencana tapak sendiri berada dalam wilayah kelas soil SD. Kata kunci : kelas soil, kecepatan gelombang geser, mikrotremor, tapak RDE, Vs30.   ABSTRACT SOIL CLASS AROUND THE SERPONG EXPERIMENTAL POWER REACTOR (EPR) SITE PLAN BASE ON MICROTREMOR DATA. Surface geological characteristics has an important role on site response analysis in a region. In regard with experimental power reactor (EPR) construction plan in Serpong, the subsurface modeling from combination array and single station microtremor data was done. The array and single station microtremor measurement were performed in 9 and 90 sites, respectively, at ± 1 km radius around the EPR site plan. The Vs30 value was calculated from shear wave velocity structure around the investigated area. The soil classification based on Vs30 in the investigated area generally consists of SD (medium soil) and SC (soft rock) class. The EPR site plan its self in the SD class region. Keyword : soil class, shear wave velocity, microtremor, EPR site, Vs30
KAJIAN PROBABILISTIK JATUHAN ABU VULKANIK TERHADAP TAPAK PLTN MURIA
Authors: Sunarko Sunarko
Published: September 2017

KAJIAN PROBABILISTIK JATUHAN ABU VULKANIK TERHADAP TAPAK PLTN MURIA.Telah dilakukan kajian probabilistik terhadap bahaya akibat jatuhan material piroklastik dari letusan hipotetik Gunung Muria di area tapak PLTN Semenanjung Muria. Tujuan kajian adalah untuk mendapatkan distribusi deposisi abu vulkanik dan nilai kebolehjadiannya di ULA terkait daya dukung beton pengungkung PLTN. Metodologi yang digunakan adalah melakukan simulasi dengan masukan data sekunder parameter letusan erupsi gunung Merapi tahun 2010 (terbatasnya data letusan Muria), dan data meteorologi sekunder berupa data rerata harian hasil olahan data pemantauan di ULA periode 1994-1995. Simulasi dilakukan berdasarkan metode skenario batas atas menggunakan kode komputer Tephra2. Hasil kajian menunjukkan bahwa distribusi abu vulkanik dominan mengarah ke arah Timur Laut – Barat Daya. Nilai kebolehjadian untuk beban > 1 kg/m2 adalah kurang dari 5%, sedangkan untuk beban > 10 kg/m2 adalah kurang dari 1%.  Jatuhan abu vulkanik akibat letusan Gunung Muria tidak membahayakan struktur bangunan PLTN yang akan dibangun di ULA.Keywords:probabilistik, tephra, skenario batas atas
A COMPARISON IN THERMAL-HYDRAULICS ANALYSIS OF PWR1000 USING FIXED AND TEMPERATURE FUNCTION OF THERMAL CONDUCTIVITY
Authors: Isnaini Muhammad Darwis , Mutiara Etty
Published: September 2017

A COMPARISON IN THERMAL-HYDRAULICS ANALYSIS OF PWR-1000 USING FIXEDAND TEMPERATURE FUNCTION OF THERMAL CONDUCTIVITY. A study to analyze theinfluence of the fuel-cladding’s thermal conductivity on the sub-channel of pressurized waterreactor 1000 (PWR-1000) using COBRA-EN computer code was conducted. The purpose ofthis research is to gain complete understanding of sub-channel thermal-hydraulic aspectsrelated to fuel performance, especially the appropriate range of thermal conductivity of UO2fuel (kf) and zircaloy-4 cladding (kc) in order to obtain an accurate sub-channel analysisrelated to its safety behavior. The research was conducted by comparing the calculation withthe combination values of the fixed kf and kc, as well as the calculation using kf and kc astemperature function. The fixed kf using in this calculation were 5.26 W/m.K, 3.85 W/m.K,3.60 W/m.K, 3.18 W/m.K, 2.90 W/m.K, 2.53 W/m.K and 2.34 W/m.K, while the kc were13.0 W/m.K, 15.57 W/m.K, 16.75 W/m.K, 17.94 W/m.K and 18.69 W/m.K. The maximumfuel center linet emperature using kf and kca s temperature function (MATPRO) for hot sub -channel was 1717.65°C and taken as the reference in accepting the calculation result usingfixed thermal conductivity. The analysis was accepted, if the deviation between bothtemperature was in the range of -10% to 10%. This analysis results for hot sub-chan nelwas accepted for the calculation using value of kf in the range of 3.18 - 2.90 W/m.K for allall variation value of kcW. hile the calculation using value of koff 2.53 W/m.K was accepet dfor value of kc in the range of 16.76 - 18.69 W/m.K
Physical Ageing of The Research Reactor Core Structural Materials Due To Neutron Irradiation Exposure: A Review
Authors: Purba Julwan Hendry
Published: September 2017

A research reactor (RR) is a nuclear reactor that has function to generate and utilize neutron flux and radiation ionization for research purposes and industrial applications. More than 60% of current operating RRs have been operated for 30 years or more. As the time passes, the functional capabilities of structures, systems and components (SSCs) of those RRs deteriorate by physical ageing, which can be caused by neutron irradiation exposure such as irradiation induced dislocation and microstructural changes. To extend the lifetime and/or to avoid unplanned outages, ageing on the safety related SSCs of RRs need to be properly managed. An ageing management is a strategy to engineer, operate, maintenance, and control SSC degradation within acceptablelimits. The purpose of this study is to review physical ageing of the core structural materials of the RRs caused by neutron irradiation exposure. In order to achieve this objective, a wide range of literatures are reviewed. Comprehensive discussions on irradiation behaviors are limited only on reactor vessel and core support structure materials made from zirconium and beryllium as well as their alloys, which are widely used in RRs. It is found that the stability of the mechanical properties of zirconium and beryllium as well as their alloys was mostly affected by the neutron fluences and temperatures.
Kajian Pra Kelayakan PLTN SMART Lepas Pantai Jenis Struktur Berbasis Gravitasi Untuk Indonesia
Authors: Lumbanraja Sahala Maruli , Dewi Dharu
Published: September 2017

KAJIAN PRA KELAYAKAN PLTN SMART LEPAS PANTAI JENIS STRUKTUR BERBASIS GRAVITASI UNTUK INDONESIA. PLTN SMART lepas pantai jenis struktur berbasis gravitasi (gravity based structure, GBS) merupakan reaktor air tekan, berdaya kecil (100 MWe), dan tapaknya berada di lepas pantai. Teknologi ini dikembangkan berdasarkan teknologi PLTN SMART yang telah ada dan teknologi pengeboran lepas pantai dengan jenis struktur berbasis gravitasi. Hal ini sebagai respons pasca kecelakaan Fukushima,  Jepang (2011), untuk meningkatkan sistem keselamatan, mengatasi keterbatasan lahan, dan meminimalisir penolakan masyarakat pada kasus PLTN di tapak daratan. Tujuan dari makalah ini adalah untuk mengkaji prakelayakan implementasi PLTN GBS di Indonesia baik dari segi kelayakan teknologi maupun regulasi. Metode yang digunakan adalah kajian pustaka dan selanjutnya dilakukan analisis deskriptif. Hasil kajian menunjukkan bahwa PLTN SMART lepas pantai patut dipertimbangkan karena menawarkan peningkatan aspek keselamatan, ketersediaan tapak lepas pantai, dan penerimaan masyarakat yang lebih baik. Sejauh ini PLTN SMART lepas pantai belum dapat diimplementasikan di Indonesia karena dibatasi oleh Peraturan Pemerintah Nomor 2 Tahun 2014 tentang Perijinan Instalasi Nuklir Dan Pemanfaatan Bahan Nuklir, yang menyatakan tapak adalah lokasi di daratan dan PLTN yang dapat dibangun di Indonesia harus sudah teruji.