bluuebunny/crossref_metadata_2025 huggingface dataset:
СТЯГНЕННЯ ПЛАТИ ЗА ЗЕМЛЮ В КОНТЕКСТІ ЗДІЙСНЕННЯ ДЕРЖАВНОГО ФІНАНСОВОГО КОНТРОЛЮ ЗЕМЕЛЬНИХ ВІДНОСИН
Authors: Ivanovа А.І.
Published: April 2019

У статті проведено аналіз структури земельних угідь України та досліджено структуру їх зміни. Визначено проблеми застосування земельних податків в Україні як одного із методів регулювання земельних відносин, ефективність державної підтримки та сучасний стан оподаткування. Проведено оцінку сучасного стану плати за землю та проаналізовано динаміку податкових надходжень до бюджету. Визначено існуючі проблеми в стягненні плати за землю. Сформульовано умови для оптимізації податкових надходжень та запропоновано механізм застосування оподаткування землі.
ДЕРЖАВНА ПІДТРИМКА АГРАРНОГО СЕКТОРУ В СУЧАСНИХ УМОВАХ ГОСПОДАРЮВАННЯ
Authors: Levandivskyi O.T.
Published: April 2019

У статті досліджено підходи до вивчення державної підтримки аграрного сектору в сучасних умовах господарювання. У ґенезі цієї проблеми показано основні підходи. Наголошується, що сучасне ведення сільського господарства тісно пов'язане з державною підтримкою. Обґрунтовуються окремі напрямки державної підтримки. При цьому вважається що державна підтримка аграрного сектору є важливим інструментом сталого розвитку держави та забезпечення її продовольчої безпеки. Однак в сучасних умовах питання організації фінансового забезпечення аграрного сектору економіки потребує нового підходу, вдосконалення розглянутих програм державної підтримки шляхом проведення активних заходів на рівні сільгосппідприємств, впровадження нових фінансово-кредитних структур. Наголошується, що при організації і веденні сільськогосподарського виробництва, а також при розробці заходів з вдосконалення його організаційно-економічного механізму необхідно враховувати, особливості сільськогосподарської діяльності без яких неможливо досягти високого рівня ефективності виробництва.
beditor: A Computational Workflow for Designing Libraries of Guide RNAs for CRISPR-Mediated Base Editing
Authors: Dandage Rohan , Després Philippe C , Yachie Nozomu , Landry Christian R
Published: April 2019

The biological relevance of the present method pertains to CRISPR-mediated base editing technology that has opened new avenues for scar-free genome-wide mutagenesis and thus to a wide range of applications in genome editing...

CRISPR-mediated base editors have opened unique avenues for scar-free genome-wide mutagenesis. Here, we describe a comprehensive computational workflow called beditor that can be broadly adapted for designing guide RNA libraries with a range of CRISPR-mediated base editors, Protospacer Adjacent Motif (PAM) recognition sequences, and genomes of many species. Additionally, to assist users in selecting the best sets of guide RNAs for their experiments, a priori estimates of editing efficiency, called beditor scores, are calculated. These beditor scores are intended to select guide RNAs that conform to requirements for optimal base editing: the editable base falls within maximum activity window of the CRISPR-mediated base editor and produces nonconfounding mutational effects with minimal predicted off-target effects. We demonstrate the utility of the software by designing guide RNAs for base editing to model or correct thousands of clinically important human disease mutations.
Composition and U–Pb (LA-ICP-MS) Isotopic Age of Zircons from Composite Dikes of Western Sangilen (Tuva-Mongolian Orogen)
Authors: Tsygankov A.A. , Burmakina G.N. , Yakovlev V.A. , Khubanov V.B. , Vladimirov V.G. , Karmysheva I.V. , Buyantuev M.D.
Published: April 2019

—Composite dikes (mingling dikes) of Western Sangilen (southeastern Tuva) are believed to indicate a shift from tectonic contraction, related to the mountain fold system formation, to postcollisional extension that ended with the disintegration of the collisional orogen. However, the position of composite dikes in the general sequence of magmatic events was based only on their geologic location and has not been confirmed by U/Pb isotope-geochronological data. The proposed study is concerned with the geologic structure, composition, and isotopic age (485–490 Ma) of West Sangilen composite dikes. The isotopic age of the host granites from the Matut pluton is 509 Ma; thermal events of Riphean (679–934 Ma) and early Paleozoic (484 Ma) age are reflected in zircons from gneiss-granites of the Erzin metamorphic complex. The obtained data are consistent with the earlier determined sequences of West Sangilen tectonometamorphic events. Basites from the examined composite dikes are strongly different in the contents of indicator elements (Rb, Nb, Ta, Zr, and Hf) and the Nb/Y, Zr/Y, Th/Ta, Zr/Nb, and Nb/Th ratios, which is indicative of different (probably, different-depth) mantle sources. The protolith of the salic component of the composite dikes might have been rocks similar in composition to the autochthonous/parautochthonous gneiss-granites of the Erzin metamorphic complex.
Deep Geoelectric Structure of the Earth’s Crust and the Upper Mantle of the Pamir–Alai Zone
Authors: Rybin A.K. , Matyukov V.E. , Batalev V.Yu. , Bataleva E.A.
Published: April 2019

—Results of profile magnetotelluric (MT) and magnetovariational (MV) soundings of the Pamir–Alai zone are presented. The problems of construction of a 2D geoelectric model of the lithosphere of the Pamir–Alai zone and its characteristics are considered. The results of the MT sounding inversion indicate the existence of a zone of lateral plastic flow in the Earth’s crust beneath the Alai depression, which manifested itself as a conductive lower-crust structure traced for at least 200 km in the E–W direction along the strike of the Alai depression. Analysis of the relationship between the parameters of the geoelectric structure and the seismicity distribution in the study region has revealed a spatial correlation between the location of the hypocenters of K > 11 earthquakes that occurred in the Pamir–Alai territory and the geoelectric structure of the Earth’s crust in this region. New data on the tectonic stratification of the Earth’s crust have been obtained, which permits us to supplement and refine the existing geological and geophysical data on the deep structure of the Pamir–Tien Shan junction zone. Conclusions about the nature of anomalous crustal conductivity in the Alai basin have been drawn.
Anti-Mullerian Hormone (AMH) and Age – An Indian laboratory retrospective analysis
Authors: Iyer Sandhya , K Kallathikumar , Sinkar Prachi , Velumani Amruta
Published: April 2019

Introduction: Anti-Mullerian Hormone (AMH) is considered to be a sensitive biological indicator of the ovarian reserve among women. Produced by the granulosa cells in the ovary, AMH is also considered to be a good biochemical marker to time menopause, apart from being monitored during treatment of certain ovarian tumors. Our retrospective report is an attempt to study AMH levels across different age-groups between 18 – 50 years of age and present age-related changes in levels.

Methods: Serum AMH estimation was done in a total of 219,227 Asian Indian women using the chemiluminescent immunoassay technology.

Results: Our analysis of different age-groups with AMH levels detected a declining trend and a significant drop in levels was recorded between ages 19 – 20 years and 35 – 36 years of age at p<0.05.

Conclusion: Our report is an attempt to present age-effect on AMH levels in a pan-India cohort of Asian Indian women and analysis detected a negative correlation between age and AMH levels.
Mitral annular calcification: Can CMR be useful in identifying caseous necrosis?
Authors: Gravina Matteo , Casavecchia Grazia , Manuppelli Vincenzo , Totaro Antonio , Macarini Luca , Di Biase Matteo , Brunetti Natale Daniele
Published: April 2019

Mitral annular calcification (MAC) can resemble an intracardiac mass and it is defined as a chronic degeneration of the mitral annulus. Often reported is caseous mitral annulus calcification (CMAC), a periannular, extensive calcification resembling a tumor. We report the case of a 68-year-old woman who had been hospitalized for palpitations and dyspnea. The transthoracic and transesophageal echocardiography revealed a non-homogeneous, slightly mobile, round mass, attached to the ventricular side of posterior mitral leaflet, with central echo-lucent area and without acoustic shadowing. Therefore, a cardiac magnetic resonance (CMR) was performed; delayed enhancement sequences showed a non-enhanced central core surrounded by a hyperenhanced rim (fibrous cap). To confirm the diagnosis, a multidetector computed tomography (MDCT) was performed; the MDCT showed a hyperdense mass with a hypodense center and a calcified peripheral rim. The central content had heterogeneous fluid density without significant contrast enhancement. The MDCT findings were considered highly suggestive of CMAC. CMR may be useful for the identification and definition of pericardial and myocardial masses and CMAC.
Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review
Authors: Maurya Anand , Singh Anurag Kumar , Mishra Gaurav , Kumari Komal , Rai Arati , Sharma Bhupesh , Kulkarni Giriraj T. , Awasthi Rajendra
Published: April 2019

Since the development of first lipid-based nanocarrier system, about 15% of the present pharmaceutical market uses nanomedicines to achieve medical benefits. Nanotechnology is an advanced area to meliorate the delivery of compounds for improved medical diagnosis and curing disease. Nanomedicines are gaining significant interest due to the ultra small size and large surface area to mass ratio. In this review, we discuss the potential of nanotechnology in delivering of active moieties for the disease therapy including their toxicity evidences. This communication will help the formulation scientists in understanding and exploring the new aspects of nanotechnology in the field of nanomedicine.
Evaluation of the Influence of Preliminary Alcoholation on Activity of Microsomal Rat Liver Factions In Vitro
Authors: Osadchenko Nazar , Knyshova Liliya , Dotsenko Anna , Tarasov Aleksandr , Yakovlev Anatoliy
Published: April 2019

The present research is devoted to the study of the relationship between the structure of the original synthetic monophenolic antioxidants and their ability to influence the activity of autophagy in tumor cells.
Comparison of Technologies for Brood Processing
Authors: Sklyar Aleksey , Bashkirtsev Nikolay , Chistyakov Sergey , Postnova Margarita
Published: April 2019

An analysis of the work of poultry farms for the processing of manure shows that the technological reason lies in the complex of objective shortcomings of the methods currently used. The article shows that modern methods of energy recovery of litter and all alternative methods of producing biofertilizers from the raw material with the technology of intensified thermophilia are not inferior to all existing ones in anything, at capital intensity and operational costs, and surpasses the alternative group in times, and energy methods by an order of magnitude.
Cleaning of Flows of Poultry Farms with Ecology Accounting and Resource Savings
Authors: Sklyar Aleksey , Postnova Margarita
Published: April 2019

The possibilities of using non-biological methods for clarifying sewage from poultry farms are presented, which testify to the high efficiency of using electrochemical technologies. Unlike biological purification, the technology of electro-chemosorption clarification provides for a rigid treatment regime, when not only minerals, organic substances are oxidized, but also microorganisms and all persistent specific contaminants falling into the poultry drains occur. It has been revealed that electro-chemisorption plants can purify effluents to the maximum permissible concentrations over a wider range of contamination levels.
Similarities and Differences of Pigments, Proteins and Lipids Composition in Native and Alien Species of the Genus Artemisia
Authors: Bogdanova Elena , Nesterov Viktor , Rozentsvet Olga , Zubova Svetlana , Makurina Olga
Published: April 2019

The genus Artemisia has about 400 species and among the plants of this genus there are native and alien species. Currently, flora’s adventitization has become one of the indicators of a powerful anthropogenic transformation of the environment, to which the flora of many regions is exposed. The study of morphological, physiological and biochemical features affecting the ability of alien species allows us to determine their rate of adaptation and the possibility of adjusting their behavior in the process of naturalization. We tried to determine the similarities and differences in the composition of key cellular components that determine the growth, development and productivity of plants in indigenous and alien species. The aim of the study was to study the quantitative content of pigments, proteins and lipids in indigenous and alien species of the genus Artemisia. The results show that alien species of A. sieversiana differ from local species by a higher content of functionally active groups of molecules, such as photosynthetic pigments, proteins and lipids. The observed differences in these groups of molecules can be due to species specificity and the genetic status of the species, as well as the place of plant growth.
The Non-Invasive System to Control Morphogenesis of Planaria as an Alternative Approach to Bioassessment
Authors: Vorobyeva Ulyana , Novikov Kirill , Burlakova Olga , Emelyanenko Viktor , Tiras Kharlampiy
Published: April 2019

The published study tests our own chemical luminescence Planaria accompanying regeneration processes in combination with methods of in vivo fixation of their structure using non-invasive computer morphometry. As a result, we propose a new system of online remote control of morphogenesis in Planaria regeneration. This system is promising for primary screening of drugs – proliferation regulators.
Estimation of the Genotoxicityof Hydrogen Peroxide and Antioxidant Actionof Halo Acid by the Method of Dna-Cometwith the Use of the Model of Transplantable Cell Cultures
Authors: Verle Olga , Ostrovskiy Oleg , Verovskiy Valerian , Dudchenko Galina
Published: April 2019

In the framework of the study, the degree of defragmentation of DNA by the DNA-comet method is evaluated when exposed to the cell culture of hydrogen peroxide (H2O2), and an in vitro model is developed to evaluate the antioxidant activity of new pharmacological agents. The results of working with cell lines show that the percentage of damage to the genetic material of cells of intact samples does not greatly vary from the method of removing the cellular monolayer from the culture plastic. Concerning the effect of H2O2 as an inducer of oxidative stress on DNA cell damage, the optimal level of DNA defragmentation has been modeled for subsequent studies of the protective action of antioxidants.
Evaluation of the Functional Condition of Human Blood Neutrophills Based on the Registrationof Active Halogen Forms Production
Authors: Grigoryeva Darya , Gorudko Irina , Lutsenko Veronika , Cherenkevich Sergey , Panasenko Oleg , Sokolov Aleksey
Published: April 2019

The development of adequate methods for monitoring the functional state of neutrophils is an urgent task due to their important role in the development of the inflammatory response. In this study, the functional activity of neutrophils has been assessed using a complex approach, including the registration of generation of ROS by neutrophils as a result of the functioning of the NADPH oxidase complex; degranulation of azurophilic granules; as well as production of AFG, formed in reactions catalyzed by the enzyme azurophilic granules of neutrophils – MPO in the presence of substrates (Н2О2 and halide ions).
Hypomagnesemia and Survival in Patients with Ovarian Cancer Who Received Chemotherapy with Carboplatin
Authors: Liu Wenli , Qdaisat Aiham , Soliman Pamela T. , Ramondetta Lois , Lopez Gabriel , Narayanan Santhosshi , Zhou Shouhao , Cohen Lorenzo , Bruera Eduardo , Yeung Sai-Ching J.
Published: April 2019

Background

Hypomagnesemia is a known side effect of several antineoplastic agents, but its impact on outcomes of patients with cancer is not well understood. We examined whether magnesium abnormalities affect survival in patients with ovarian cancer who receive chemotherapy containing carboplatin.

Materials and Methods

We included patients with advanced ovarian cancer who had undergone surgery and chemotherapy between January 1, 2004, and December 31, 2014, at our institution. Inclusion criteria were age 18 years or older, pathology of high-grade serous carcinoma, first treatment (surgery or chemotherapy) within 60 days of diagnosis, and chemotherapy containing carboplatin. The final cohort consisted of 229 patients. Vital signs and laboratory tests were recorded at baseline and during the treatment course. The associations between magnesium abnormalities (and other clinical characteristics) and survival were analyzed.

Results

The median patient age was 64 years. Higher baseline heart rate (beats per minute; hazard ratio [HR] = 1.02, p = .002) and greater frequency of hypomagnesemia during the treatment course (HR = 1.05, p = .002) were significantly associated with shorter survival independent of completeness of tumor reduction (HR = 1.60, p = .02), and International Federation of Gynecology and Obstetrics stage (HR = 1.63, p = .01).

Conclusion

Baseline heart rate and the frequency of hypomagnesemia episodes during treatment are prognostic of survival for patients with advanced ovarian cancer receiving carboplatin-containing chemotherapy and tumor reductive surgery. Future research is needed for strategies to detect and prevent hypomagnesemia in this patient population.
Lenalidomide in Pretreated Patients with Diffuse Large B-Cell Lymphoma: An Italian Observational Multicenter Retrospective Study in Daily Clinical Practice
Authors: Broccoli Alessandro , Casadei Beatrice , Chiappella Annalisa , Visco Carlo , Tani Monica , Cascavilla Nicola , Conconi Annarita , Balzarotti Monica , Cox Maria Christina , Marino Dario , Goldaniga Maria Cecilia , Marasca Roberto , Tecchio Cristina , Patti Caterina , Musuraca Gerardo , Devizzi Liliana , Monaco Federico , Romano Alessandra , Fama Angelo , Zancanella Michelle , Paolini Rossella , Rigacci Luigi , Castellino Claudia , Gaudio Francesco , Argnani Lisa , Zinzani Pier Luigi
Published: April 2019

Background

Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma subtype, and approximately 50% of the patients are >60 years of age. Patients with relapsed/refractory (rr) disease have a poor prognosis with currently available treatments. Lenalidomide is available in Italy for patients with rrDLBCL based on a local disposition of the Italian Drug Agency.

Subjects, Materials, and Methods

An observational retrospective study was conducted in 24 Italian hematology centers with the aim to improve information on effectiveness and safety of lenalidomide use for rrDLBCL in real practice.

Results

One hundred fifty-three patients received lenalidomide for 21/28 days with a median of four cycles. At the end of therapy, there were 36 complete responses (23.5%) and 9 partial responses with an overall response rate (ORR) of 29.4%. In the elderly (>65 years) subset, the ORR was 33.6%. With a median follow-up of 36 months, median overall survival was reached at 12 months and median disease-free survival was not reached at 62 months. At the latest available follow-up, 29 patients are still in response out of therapy. Median progression-free survivals differ significantly according to age (2.5 months vs. 9.5 in the younger vs. elderly group, respectively) and to disease status at the latest previous therapy (15 months for relapsed patients vs. 3.5 for refractory subjects). Toxicities were manageable, even if 30 of them led to an early drug discontinuation.

Conclusion

Lenalidomide therapy for patients with rrDLBCL is effective and tolerable even in a real-life context, especially for elderly patients.

Implications for Practice

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma, and approximately 50% of the patients are >60 years of age. Patients with relapsed/refractory (rr) disease have a poor prognosis, reflected by the remarkably short life expectancy of 12 months with currently available treatments. The rrDLBCL therapeutic algorithm is not so well established because data in the everyday clinical practice are still poor. Lenalidomide for patients with rrDLBCL is effective and tolerable even in a real-life context, especially for elderly patients.
Eco-efficient preplaced recycled aggregate concrete incorporating recycled tyre waste
Authors: Alfayez Saud A , Omar Tarek , Nehdi Moncef L
Published: April 2019

This experimental study explores the development of highly eco-efficient concrete. This concrete incorporates 50% higher coarse aggregate content compared with normal concrete, thus reducing cement demand, and its granular skeleton is entirely recycled. Moreover, it adopts a unique energy-efficient placement technique whereby the granular skeleton is first preplaced in the form and then injected with a flowing grout, which considerably reduces the energy of mixing and placement. Various mixtures incorporating recycled concrete aggregate along with recycled rubber granules and steel wire fibres retrieved from scrap tyres were made. The mechanical strength and post-cracking behaviour of the eco-efficient concrete were evaluated. While tyre rubber decreased mechanical strength as expected, scrap tyre steel wire fibres enhanced the tensile and flexural behaviour, exhibiting superior energy absorption and ductility compared to the brittle failure of the control mixture. The results provide an insight into the level of recycled tyre rubber and steel wire that could be combined with recycled concrete aggregate to achieve durable and cost-effective eco-efficient preplaced recycled aggregate and rubberised concrete for sustainable non-structural applications.
Abstracts of current foreign publications
Authors: Akhaladze G. G. , Akhaladze D. G.
Published: April 2019

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EUS-assisted biliodigestive anastomoses for malignant mechanical jaundice
Authors: Rudakova M. N. , Ryabov K. Yu. , Zhevelyuk A. G. , Trandofilov M. M. , Prokhorov A. V. , Popov A. Yu.
Published: April 2019

Aim. To assess the role of endoscopic ultrasonography (EUS) in bile duct drainage for malignant mechanical jaundice followed by abnormal anatomy of upper gastrointestinal tract.

Material and methods. There were 43 attempts to form EUS-assisted biliodigestive anastomoses in 43 patients for the period 2014–2018. Procedure was successful in 33 (76.74%) patients.

Results. Two periods were identified to analyze the results. The first period (2014–2015) included 21 patients who underwent surgery, the second period (2016–2018) – 22 patients. In the first period, the effectiveness of EUS-assisted procedures was 57%, in the second one – 96%.

Conclusion. EUS-assisted biliodigestive anastomoses are useful for biliary decompression in various anatomical situations including switching off the duodenum from food passage. These operation is safe alternative to other types of decompression with accumulation of experience.
The results of endosonography-assisted internal drainage of pancreatic pseudocyst
Authors: Starkov Yu. G. , Zamolodchikov R. D. , Dzhantukhanova S. V. , Vyborniy M. I. , Lukich K. V. , Ibragimov A. S. , Goncharov I. M. , Lavrentyeva V. Yu.
Published: April 2019

Aim.To compare immediate and long-term results of internal drainage of pancreatic pseudocyst by using of endosonography-assisted and open surgical approaches.

Material and methods.EUS-assisted internal drainage of pancreatic pseudocyst was performed in 32 patients in 2011–2016. Open drainage procedures were carried out on the other 32 patients.

Results.In the group of endoscopic drainage, technical success rate, clinical success rate and complication rate were 97%, 85% and 26%, respectively. There were no recurrent pseudocysts in long-term period. Comparison with open surgery confirmed advantages of endoscopic technique regarding time of operation (p< 0.01), intraoperative blood loss (p< 0.01) and length of hospital-stay (p< 0.01).

Conclusion.EUS-assisted internal drainage of pancreatic pseudocysts in the treatment of chronic pancreatitis is characterized by high rate of technical and clinical success, small postoperative morbidity and low incidence of longterm recurrences.
Bile duct injuries and systemic approach to the treatment
Authors: Romashchenko P. N. , Maystrenko N. A. , Pryadko A. S. , Aliev A. K.
Published: April 2019

Aim.Present a program of examination and treatment of patients with biliary duct injury, corresponding to the level of the international protocol and modern requirements for the quality of medical care.

Material and methods.The results of examination and treatment of 77 patients with bile ducts injuries are analyzed. The analysis of the main surgical interventions for the elimination of bile ducts injuries is given: reconstructive operations in 44.3% of patients, recovery operations – in 36.7% and external drainage – in 19%.

Results.A program approach has been developed to assist patients with bile duct injuries in civil health care at various levels of surgical care.

Conclusions.The implementation of this program provides timely diagnosis of damage to the bile duct and minimizing the number of postoperative complications at the second and third levels of surgical care. It was determined that a rational approach to reduce the number of injuries of the bile ducts is their prevention by perfect adherence to the technique of surgical intervention on the organs of the upper floor of the abdominal cavity, and to reduce the number of negative consequences, the proposed algorithm for diagnosis and treatment.
X-ray surgery for benign biliary strictures after cholecystectomy
Authors: Okhotnikov O. I. , Yakovleva M. V. , Gorbacheva O. S.
Published: April 2019

Aim.To determine the role of antegrade X-ray surgical interventions in the treatment of benign postoperative biliary strictures.

Material and methods.A retrospective analysis of treatment of 36 patients with benign biliary strictures was performed. Isolated stricture of biliodigestive anastomosis was diagnosed in 25 cases, partial clipping of common hepatic duct proximal to biliodigestive anastomosis – in 3 cases, partial clipping of bile duct – in 3 patients, isolated biliary strictures – in 5 patients including 4 of them with stricture within previously deployed T-shaped drainage. At the first stage, percutaneous transhepatic cholangiostomy was performed. According to antegrade cholangiography data, structure type “+1, +2” by H. Bismuth classification in modification of E. I. Galperin was diagnosed in 16 (55.2%) patients, proximal biliary strictures (“0”–“−2”) in 13 patients. Three patients with partial clipping of common bile duct and 4 patients with benign biliary stricture in the area of previously deployed T-shaped drainage were not classified. Recanalization of strictures by “catheter-guide” system was followed by antegrade dilatation of the stricture. Final stage was frame external-internal drainage for 6–12 months with stepwise redo balloon dilatation every 3 months (35 patients). The criterion for the end of minimally invasive treatment was the absence of balloon waist in the stricture zone observed during the next procedure but not earlier than in 6 months from primary balloon dilatation. Surgical correction was indicated for recurrent stricture.

Results.Direct technical success was achieved in 35 patients. There was 1 case of recurrent strictures within 1 year among 3 cases of primary repair of biliary strictures in the area of previously installed T-shaped drainage. Resection of common bile duct stricture was followed by Roux-en-Y hepaticojejunostomy. Recurrence-free period among 36 patients ranged from 1 to 10 years, median – 56 months. There were no mortality and complications after X-ray surgery.

Conclusion.Antegrade recanalization and balloon dilatation of the stricture followed by long-term external-internal biliodigestive frame drainage are effective for both stricture of biliodigestive anastomosis and partial clipping of bile duct. Conventional surgical procedures should be preferred for cicatricial strictures of extrahepatic bile ducts after previous T-shaped drainage deployment.
QUALIDADE DE PELLETS DE GALHOS SECOS DE ARAUCÁRIA E PARTÍCULAS DE PINUS
Authors: Brand Martha Andreia , Jacinto Rodolfo Cardoso , Da Cunha Alexsandro Bayestorff
Published: April 2019

As grimpas de araucária, quando permanecem sem uso nos campos nativos, se constituem em um problema de sanidade animal para a atividade pecuária extensiva. Os resíduos da madeira de Pinus, largamente utilizada na indústria de base florestal no sul do Brasil, são a principal matéria-prima para a produção de pellets, no Brasil e no mundo. Assim, a análise da produção de pellets com estas duas matérias-primas pode ser uma alternativa para a utilização sustentada destes resíduos. O objetivo deste trabalho foi caracterizar energeticamente as grimpas, comparando-as com as propriedades do Pinus, e os pellets obtidos a partir de diferentes misturas destes dois tipos de biomassa. Os parâmetros qualitativos foram enquadrados na norma ISO 17225-2 para determinar a melhor aplicação energética dos compactados. As propriedades físicas, químicas e energéticas foram determinadas nas grimpas e partículas de Pinus na forma in natura. Pellets com as proporções de 0:100%; 25:75%; 50:50%, 75:25% e 100:0% de partículas de Pinus:grimpas foram produzidos e nestes foram determinadas as propriedades físicas e energéticas, sendo enquadradas nos parâmetros da norma ISO 17225-2. Na forma in natura, a maravalha de Pinus e a grimpa apresentaram potencial energético distinto, sendo que as propriedades de cada biomassa influenciaram de forma diferente na qualidade dos pellets. Os pellets obtidos da mistura das biomassas tiveram melhor qualidade do que os pellets homogêneos. Os pellets homogêneos de Pinus ou de grimpa não atenderam plenamente nenhuma das categorias de uso da norma ISO 17225-2, enquanto os pellets das misturas apresentaram potencial para uso doméstico e comercial.
COMPARAÇÃO DO CONSUMO ENERGÉTICO ENTRE BRASIL E HONDURAS E SUA DEPENDÊNCIA DE FONTES NÃO RENOVÁVEIS
Authors: Hernandez Vindel Sindy Michell , Campos Sérgio , Spadotto Anselmo José , Manfrin Garcia Yara
Published: April 2019

As modificações na matriz energética brasileira e hondurenha com o propósito de torná-las mais eficientes e procurando contribuir com o desenvolvimento ambiental configuram o tema de interesse desta pesquisa. O trabalho objetivou realizar a comparação do consumo energético por setor da matriz energética brasileira e hondurenha e sua dependência de energia não renovável. Os países envolvidos nesta pesquisa são Brasil e Honduras ambos estão localizados na América Latina, com uma extensão territorial de 8.516.000 km2 e 112.492 km2 respectivamente. A metodologia empregada foi qualitativa por meio de uma pesquisa de sondagem, onde se procuraram informações referentes ao objetivo deste trabalho. Foram consultados artigos científicos em sites especializados, os dados estatísticos do consumo energético foram obtidos de organizações internacionais. Como resultados encontrou-se que ambos países são dependentes de energia não renovável para poder cobrir a demanda energética, mas estão indo pelo caminho correto na diversificação de sua matriz energética.
PISA 2003 ve 2012 Matematik Okuryazarlığı Puanlarının Ölçüt Geçerliği: Beklenti Tabloları ve Uyum Analizi
Authors: KILIÇ Abdullah Faruk , ERDEM-KARA Başak , DOĞAN Nuri
Published: April 2019

Bu çalışmanın amacı PISA 2003 ve 2012 matematik okuryazarlığı

puanlarının ölçüt geçerliğini beklenti tabloları ve uyum analizi yardımıyla

araştırmaktır. Bu amaçla PISA 2003 ve 2012 problem çözme becerileri puanları

kullanılmıştır. Puanlar 3 farklı şekilde kategorize edilmiştir. İlk olarak PISA

tarafından kullanılan puan aralıkları kullanılmıştır. Ancak PISA puanlarını 357

ve altını da bir kategori kabul ederek 7 kategori oluşturulmuştur. Ayrıca puan

aralıkları %10 ve %20’lik dilimlere bölünerek beklenti tabloları oluşturulmuş,

damlacık grafikleriyle görsel olarak yorumlanması sağlanmış ayrıca kategoriler

arasındaki uyumu incelemek için uyum analizi yapılmıştır. Araştırma sonucunda

matematik puanlarının %20’lik dilimler halinde kategorize edildiğinde %10’luk dilimlere

göre daha uyumlu sonuçlar elde edildiği, beklenti tablolarında oranların

yükseldiği gözlenmiştir. PISA puan kategorisinde matematik puan kategorileriyle

problem çözme puanı kategorilerinin benzer olduğu söylenebilir.
Hayat Bilgisi Dersinde Dijital Bir Değerlendirme
Authors: SÜRAL İrfan , GİRMEN Pınar
Published: April 2019

Bu çalışmanın amacı, hayat bilgisi dersinde dijital bir değerlendirme aracı geliştirmek ve uygulama sürecini betimlemektir. Bu amaç doğrultusunda nitel ve nicel araştırma yaklaşımlarının birlikte kullanıldığı karma desenden yararlanılmıştır. Araştırmanın katılımcılarını orta sosyo-ekonomik çevreye sahip bir okulun birinci sınıfına devam eden 32 öğrenci ve bu sınıfların öğretmenleri oluşturmuştur. Araştırmanın nicel verileri; öğrencilerin oyun sürecindeki hamle sayıları, oynarken geçirdikleri süre ve elde ettikleri skorlara dayalı olarak toplanmıştır. Araştırmanın nitel boyutundaki veriler sınıf öğretmenleriyle gerçekleştirilen yarı yapılandırılmış görüşmeler aracılığıyla toplanmıştır. Araştırma bulgularına göre; geliştirilen dijital değerlendirme aracının uygulama sürecinde öğrencilerin teknoloji kulanım becerileri konusunda sorunlar yaşadıkları öte yandan aracı kullanmaktan keyif aldıkları belirlenmiştir.
Türkiye’de Tartışmalı ve Sosyobilimsel Konular Üzerine Yazılan Lisansüstü Tezlerin Eğitim Bilimleri Perspektifinden İncelenmesi
Authors: TATAR Şefika , ADIGÜZEL Oktay Cem
Published: April 2019

Bu çalışma kapsamında, 2007-2016 yılları arasında

Türkiye’de tartışmalı ve sosyobilimsel konular üzerine gerçekleştirilen

tezlerin yüksek lisans ve doktora düzeylerine, yıllara ve anabilim/bilim

dallarına, konu alanlarına ve araştırma modellerine göre dağılımlarının

incelenmesi amaçlanmıştır. Betimsel tarama modelinde desenlenen bu çalışmada

tezler, araştırmacı tarafından hazırlanan bir betimsel analiz formu

doğrultusunda incelenmiştir. Yapılan analizler sonucunda tartışmalı ve

sosyobilimsel konuların ağırlıklı olarak ilköğretim ve yükseköğretim

düzeyindeki tezlerde araştırma konusu yapıldığı tespit edilmiştir. Tartışmalı

ve sosyobilimsel konular üzerine yapılan çalışmaların konu alanları

incelendiğinde çalışmaların yoğunluklu olarak fen ve biyoetik konularında

gerçekleştirildiği, bunların dışında kalan konularda çok sınırlı sayıda kaldığı

gözlenmiştir. Sosyobilimsel konuların bilişsel beceriler üzerindeki etkisi en

çok araştırılan konu olurken; bu konularla ilgili duyuşsal beceriler en çok

araştırılan ikinci konu olmuştur
Front Matter Vol 6 No 1 Tahun 2018
Authors: Setiawan Yana
Published: April 2019

Front Matter Vol 6 No 1 Tahun 2018
Pengaruh Kecukupan Modal dan Risiko Kredit Terhadap Likuiditas Pada Bank Umum Syariah Yang Terdaftar di Bank Indonesia
Authors: Gautama Budhi Pamungkas , Annisa Rizka , Waspada Ikaputera
Published: April 2019

AbstractThis research is based on the increasing number of liquidity of Islamic General Bank which is registered in Bank of Indonesia. The aim of this research is to find out the image of capital adequacy by using CAR indicator, credit risk by using NPF indicator and examine the impact of capital adequacy and credit risk towards the liquidity of islamic general bank which is registered in Bank of Indonesia. The research method used in this research is descriptive and verification method. This research used capital adequacy secondary data, credit risk and liquidity which are based on the financial statements from each bank which have been managed in 2012-2016 period. The analysis technique for this research was by using classical assumption test, regression analysis panel data and hypothesis test. This study used purposive sampling in islamic general bank registered in Bank of Indonesia in 2012-2016 period. This research was done by panel data analysis that was assisted by an application named Eview 8. Based on regression significance test, the capital adequacy and credit risk have influenced the liquidity itself. Based on the regression coefficient test, the capital adequacy gave significant positive effect to the liquidity, while the credit risk gave significant negative effect to liquidity. Keywords. capital adequacy; credit risk; liquidity   AbstrakPenelitian ini dilatarbelakangi oleh meningkatnya likuiditas pada Bank Umum Syariah yang terdaftar di Bank Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui gambaran kecukupan modal dengan menggunakan indikator CAR, risiko kredit dengan menggunakan indikator NPF dan likuiditas dengan menggunakan indikator FDR serta menguji pengaruh kecukupan modal dan risiko kredit terhadap likuiditas pada bank umum syariah yang terdaftar di Bank Indonesia. Metode penelitian yang dilakukan dalam penelitian ini yaitu dengan menggunakan metode deskriptif dan verifikatif. Data yang digunakan dalam penelitian ini adalah data sekunder kecukupan modal, risiko kredit dan likuiditas yang bersumber dari laporan keuangan dari masing-masing bank yang sudah diolah periode 2012-2016. Teknik analisis yang dilakukan dalam penelitian ini dengan menggunakan uji asumsi klasik, analisis regresi data panel dan uji hipotesis. Penelitian ini menggunakan teknik penelitian dengan cara purposive samplingpada bank umum syariah yang terdaftar di Bank Indonesia periode 2012-2016. Penelitian ini dilakukan menggunakan analisis data paneldengan dibantu oleh aplikasi Eviews 8. Berdasarkan uji keberartian regresi, kecukupan modal dan risiko kredit berpengaruh terhadap likuiditas. Berdasarkan uji koefisien regresi, kecukupan modal berpengaruh positif signifikan terhadap likuiditas, sedangkan risiko kredit berpengaruh negatif signifikan terhadap likuiditas. Kata kunci. kecukupan modal; risiko kredit; likuiditas
Analisis Penerapan Metode Activity Based Costing dalam Menentukan Harga Sewa Kamar Hotel
Authors: Faishal Fahmi Hikmah , Mulyani Heni , Yulianti Leni
Published: April 2019

Abstract.This study aims to find out how the application of hotel room rental prices by using activity based costing at de’Kayakini Bandung hotels. This study uses descriptive research methods. Descriptive research to determine the difference in activity based costing methods with traditional methods. In this study there is only one type of variable used, namely rent. The rental price is the amount of money that will be paid for something to be received, the rental price in this study is the selling price. The data sources used in this study are secondary data sources. Secondary data is obtained from Hotel De’Kayakini in the form of hotel cost reports. The results of the study show that from the calculation of the cost of rooms using the activity based costing method, the lower cost of goods is obtained compared to the traditional cost accounting method.Keywords. activity based costing; room rental prices AbstrakPenelitian ini bertujuan untuk untuk mengetahui bagaimana penerapan harga sewa kamar hotel dengan menggunakan activity based costing pada hotel de’Kayakini Bandung. Penelitian ini menggunakan metode penelitian deskriptif. Penelitian deskriptif untuk mengetahui perbedaan metode activity based costing dengan metode tradisional. Dalam penelitian ini terdapat hanya satu jenis variabel yang digunakan yaitu harga sewa. Harga sewa adalah sejumlah uang yang akan dibayarkan untuk sesuatu hal yang akan diterima, harga sewa dalam penelitian ini adalah harga jual. Sumber data yang digunakan dalam penelitian ini, merupakan sumber data sekunder. Data sekunder didapatkan dari Hotel De’Kayakini berupa laporan biaya hotel. Hasil penelitian menunjukkan bahwa dari perhitungan harga  pokok kamar dengan menggunakan metode activity based costing diperoleh harga pokok yang lebih rendah dibandingkan dengan metode traditional cost accounting.Kata kunci. activity based costing; harga sewa kamar
Pengaruh Leverage Keuangan Terhadap Profitabilitas Pada Perusahaan Sub-Sektor Telekomunikasi Yang Terdaftar Di Bursa Efek Indonesia
Authors: Christian Jogi , Supriyatna Yayat , Faruk Umar
Published: April 2019

Abstract.This study aims to describe the financial leverage and profitability of the company and how the influence of financial leveraege on profitability in the telecommunications sub-sector companies listed on the Indonesia Stock Exchange. With survey research through descriptive and verification methods, the research sample was 4 telecommunications companies in the period 2007-2016. The sampling technique uses Purposive Sampling, while the analysis technique uses simple linear regression using the help of EViews software 9. Based on the descriptive analysis of financial leverage from year to year it tends to be relatively up and fluctuating profitability but is quite decreased compared to the initial year of the study. The effect of financial leverage on profitability is 56% while the remaining 44% is influenced by other factors, the results of hypothesis testing indicate that the effect of financial leverage on profitability has a significant negative effect so that the results of the study can be generalized to the population. Keywords. Financial Leverage; DAR; Profitability, ROA AbstrakPenelitian ini bertujuan untuk mengetahui gambaran leverage keuangan dan profitabilitas perusahaan serta bagaimana pengaruh leveraege keuangan terhadap profitabilitas pada perusahaan sub-sektor telekomunikasi yang terdaftar di Bursa Efek Indonesia. Dengan penelitian survey melalui metode deskriptif dan verifikatif, sampel penelitian adalah 4 perusahaan telekomunikasi pada periode 2007-2016. Teknik sampling menggunakan Purposive Sampling, sedangkan teknik analisis menggunakan regresi linier sederhana menggunakan bantuan software EViews 9. Berdasarkan analisis deskriptif leverage keuangan dari tahun ke tahun cenderung relatif naik dan profitabilitas fluktuatif namun cukup menurun jika dibandingkan dengan tahun awal penelitian. Pengaruh leverage keuangan terhadap profitabilitas sebesar 56% sementara sisanya 44% dipengaruhi oleh faktor lain, hasil uji hipotesis menunjukkan bahwa pengaruh leverage keuangan terhadap profitabilitas berpengaruh negatif signifikan sehingga hasil penelitian dapat digeneralisasikan kepada populasi. Kata Kunci. Leverage Keuangan, DAR, Profitabilitas, ROA
Front Matter Vol 6 No 2 Tahun 2018
Authors: Setiawan Yana
Published: April 2019

Front Matter Vol 6 No 2 Tahun 2018
Pengaruh Pendapatan Garansi Bank Terhadap Laba Operasional
Authors: Sugiyanto Sugiyanto
Published: April 2019

AbstractThis research was conducted to determine influence of the bank guarantee revenue to the operating profit at PT Bank BJB Tbk Cabang Utama Bandung Period from January to December 2015. This research used a quantitative method. Data collection techniques used observation and literature study. The writer used Pearson correlations analysis, determination and Regression. The result showed that the correlation between revenue of bank guarantee and operating profit at PT. Bank BJB Tbk Cabang Utama Bandung Period from January to December 2015 had a vey low relationship with level of correlation coefficient as much as 0,189. While the influence of guarantee bank to operating profit was found to be 0,36% and the remaining of 99,64% was influenced by other factors which were not observed by the writer. There were obstacles in this research, such as; incompleteness of supporting document, there was collectability of customers at the time of analysis BI – Checking, as well as the legality of the company that were not updated or a change of leadership. The suggestion for the company is to improve the publishing process faster, in order to increase customer’s confidence so that an application for a bank guarantee will be more and income on bank guarantee will be even greater.Keywords. bank guarante revenue; operating profit.Abstrak Penelitian ini dilakukan untuk mengetahui pengaruh pendapatan garansi bank terhadap laba operasional pada PT Bank BJB Tbk Cabang Utama Bandung Periode Januari - Desember 2015. Penelitian ini menggunakan metode penelitian kuantitatif, teknik pengumpulan data melalui wawancara, observasi, dan studi kepustakaan. Peneliti menggunakan analisis Pearson, determinasi, dan Regresi Sederhana. Hasil penelitian menunjukkan bahwa keterkaitan pendapatan garansi bank dan laba operasional pada PT Bank BJB Tbk Cabang Utama Bandung mempunyai tingkat hubungan sangat rendah dengan nilai koefisien korelasi sebesar 0,189. Sedangkan besar pengaruh pendapatan garansi bank terhadap laba operasional ditemukan sebesar 0,36% dan sisanya sebesar 99,64% dipengaruhi faktor lainnya yang tidak diteliti oleh penulis. Adapun kendala dalam penelitian ini yaitu ketidaklengkapan dokumen pendukung, terdapat kolektabilitas nasabah pada saat analisis BI – Checking serta legalitas perusahaan yang sudah tidak update atau ada perubahan kepemimpinan. Adapun saran untuk perusahaan yaitu sebaiknya meningkatkan proses penerbitan lebih cepat, agar kepercayaan nasabah meningkat sehingga permintaan untuk penetbitan garansi bank lebih banyak dan pendapatan atas penerbitan garansi bank akan semakin besar.Kata Kunci. laba operasional; pendapatan garansi bank.
Determinan Motivasi, Partisipasi Anggaran, dan Komunikasi Terhadap Kinerja Organisasi dengan Kepuasan Kerja Sebagai Variabel Intervening
Authors: Mudawanah Siti
Published: April 2019

AbstractThis study aims to analyze the effect of motivation, budget participation and communication on organizational performance with job satisfaction as an intervening variable. There are results of previous studies that are inconsistencies regarding the effect of budget participation on performance so motivating in conducting this research. The research method uses a quantitative method, an analytical tool that is SmartPLS Version 3.0. The population of this study is all universities in Lebak Regency, the sample method uses saturated samples. The results of the study show that communication and job satisfaction have a significant effect on organizational performance. Then, motivation and communication on organizational performance with job satisfaction as an intervening variable have a significant influence. Whereas, motivation and budget participation do not have a significant effect on organizational performance and budget participation on organizational performance with job satisfaction as an intervening variable that does not have a significant effect. Keywords: job satisfaction; organizational performance; communication; motivation; budget participation. AbstrakPenelitian ini bertujuan menganalisis pengaruh  motivasi, partisipasi anggaran dan komunikasi terhadap kinerja organisasi dengan kepuasan kerja sebagai variabel intervening. Terdapat hasil penelitian sebelumnya yang inkonsistensi mengenai pengaruh partisipasi anggaran terhadap kinerja sehingga memotivasi dalam melakukan penelitian ini. Metode penelitian menggunakan metode kuantitatif,  alat analisis yaitu perangkat lunak SmartPLS Versi 3.0. Populasi penelitian ini seluruh perguruan tinggi di wilayah Kabupaten Lebak, metode sampel menggunakan sampel jenuh. Hasil penelitian menunjukkan komunikasi, dan kepuasan kerja berpengaruh signifikan terhadap kinerja organisasi. Kemudian, motivasi dan komunikasi terhadap kinerja organisasi dengan kepuasan kerja sebagai variabel intervening memiliki pengaruh signifikan. Sedangkan, motivasi dan partisipasi anggaran tidak berpengaruh signifikan terhadap kinerja organisasi dan partisipasi anggaran terhadap kinerja organisasi dengan kepuasan kerja sebagai variabel intervening tidak memiliki pengaruh signifikan. Kata Kunci: kepuasan kerja; kinerja organisasi; komunikasi;  motivasi; partisipasi anggaran.