bluuebunny/crossref_metadata_2025 huggingface dataset:
Multicomponent approach to the synthesis and spectral characterization of some 3,5-pyrazolididione derivatives and evaluation as anti-inflammatory agents
Authors: El-Ossaily Yasser A. , Alanazi Nuha M. M. , Althobaiti Ibrahim O. , Altaleb Hamud A. , Al-Muailkel Nayef S. , El-Sayed Mohamed Y. , Hussein Modather F. , Ahmed I. M. , Alanazi Maha M. , Fawzy Ahmed , Abdel-Raheem Shaban A. A. , Tolba Mahmoud S.
Published: October 2023

Pyrazolones are a class of heterocyclic compounds that contain a pyrazole ring fused to a ketone group. Recent scientific research has focused extensively on the potential anti-inflammatory properties of pyrazolone compounds due to their diverse pharmacological effects in alleviating inflammation and reducing fever. This motivated us to focus on the preparation of these derivatives in a simple and eco-friendly manner. A convenient new green methodology was modified for the preparation of 1-phenyl-3,5-pyrazolidinedione by the sonicated MCR of diethyl malonate, phenylhydrazine, and a catalytic amount imidazole as homogenous organic catalyst in water green solvent in a good yield. On the other hand, some of 4-arylidinepyrazolidinedione derivatives are prepared in the same manner via the treatment of a mixture of diethyl malonate, phenylhydrazine, aromatic aldehydes, and a catalytic amount of imidazole in an aqueous medium. Our target synthesized pyrazolidinediones were elucidated via elemental and several spectral analyses. Due to the importance of pyrazolidinediones in the field of treating inflammation and relieving pain, a number of prepared compounds were chosen to test their efficacy as anti-inflammatory agents using carrageenan-induced foot edema in rats and compare the results with indomethacin, the standard drug. We found that the majority of derivatives yield promising results spanning from good to wonderful, so derivatives (15k, 15b, 15h, 15a, and 15j) yield the best results while derivative (15i) yields an average result. As for the derivative (15f), it yields the lowest results compared to the standard drug. This is due to the difference in the structural composition of these derivatives, which increases the likelihood of their use as anti-inflammatory derivatives.
New biocidal hybrids bearing acridine and aminophosphonate Scaffolds against different bacterial pathogens
Authors: Gomaa Heba Ramadan , Aleem Abdel Aleem Hassan Abdel , Salman Ayah Usama , El-Sayed Ibrahim E.T.
Published: October 2023

New hybrids containing acridine and α-amino phosphonate scaffolds 6a-h were synthesized by three one-pot reactions via Kabachnik–Fields reaction of 9-aminoacridine derivatives 3a-d, aldehydes 4a,b and triphenyl phosphite 5 in equimolar ratio under stirring at room temperature. The installation of the afforded hybrids was affirmed by different spectroscopic methods as IR, 1HNMR, 13CNMR, 31P NMR, MS and elemental analysis. The antibacterial activities of hybrids 6a-h were screened against both Gram-positive and Gram-negative bacteria of four pathogenic strains, comparable to ampicillin and chloramphenicol drugs. Most hybrids showed higher activity compared to the reference drugs. Notably, the antibacterial performance of 6c was more substantial than other analogues with best minimum inhibitory concentration (MIC) and highest zone of inhibition (ZOI) of 31, 34, 35, 38 mm, against Serratia marcescens, Streptococcus mutans, MRSA and Klebsiella pneumoniae clinical isolates respectively. In addition, Transmission Electron Microscopes (TEM) was carried out to study the mode of action of 6c with MRSA, the results confirmed that the titled hybrid caused the disruption of bacterial cell wall. Moreover, the time-dependent kill study revealed that the investigated compounds were time and dose-effective bactericidal agents and could be used as potential leads for further development and optimization of novel antibacterial agents.
Efficient and reusable Pumice supported perchloric acid catalyst for concise and effective synthesis of 1,8-dioxo-octahydroxanthenes under solvent free condition
Authors: Tambe Adinath , Shirole Gopinath , Dange Chaitali , Gavande Jayshri , Narode Rahul , Uphade Bhagwat , Rana Suprita
Published: October 2023

In the present investigation, a library of 1,8-dioxo-octahydroxanthene derivatives have been synthesised by the cyclo-condensation reaction of aryl aldehyde with two moles of dimedone under solvent free condition in the presence of Novel Pumice supported perchloric acid (Pumice@HClO4) as a less expensive, recyclable, thermodynamically stable and non-toxic catalyst. The significant advantages of this novel protocol are experimental simplicity, easy work-up procedure, good to excellent yields of product and more sustainable as the efficiency of the readily available catalytic material.
Nitro-functionalized analogues of 1,3-Butadiene: An overview of characteristic, synthesis, chemical transformations and biological activity
Authors: Sadowski Mikołaj , Kula Karolina
Published: October 2023

The nitrovinyl moiety is surely one of the most reactive fragments in organic chemistry, continuously employed to explore original pathways and reach new targets. One of the most important classes of chemicals containing this fragment are nitro-functionalised analogues of 1,3-butadiene. In this paper a comprehensive review study of these compounds is performed. The manuscript includes an analysis of physicochemical properties, spectral characteristic, synthesis, biological activity, and possible transformations of nitro substituted analogues of 1,3-butadiene. The analysis was divided into several parts, depending on the number of nitro groups included in the structure of a 1,3-butadiene analogue. In addition, the work includes information about hazards and safety principles when working with nitro compounds. Based on the analysis of the literature, it can be concluded that nitro-functionalised analogues of 1,3-butadiene exhibit diversified profile of properties, and an outstanding potential as valuable reagents in organic synthesis useful to obtain heterocycles that can be applied in medicine.
A Study to Assess the effect of Jigsaw Learning Technique to Learn the Concept of Preeclampsia among Fourth year B.Sc. Nursing students of TMM College of Nursing, Tiruvalla
Authors: Jose Smitha , M J Manjima , Alex Nidhi , M Thampi Santy
Published: October 2023

Learning and reproducing the contents learnt during examination is a part of every student’s life especially in professional courses like nursing where the entire curriculum is made concise into four years. Making the teaching and learning strategies more student-friendly has helped to retain student’s attention and insist in them the interest to learn and perform better. Jigsaw Technique is one of the cooperative learning technique in which students equally participates, prepares and leads a group thus learning for themselves as well as preparing for their group. The purpose of this study was to investigate the impact of jigsaw learning technique on nursing students in learning a concept of Preeclampsia, as it is found beneficial in teaching. The technique also helps to revolve the learning material for peers in learning process and thereby help to build interpersonal and interactive skills among students. 50 B.Sc nursing students were selected and their pre-knowledge level on the concepts of preeclapmpsia was assessed. The same group was taught the Jigsaw Technique of learning to study the concept and the students were divided into 5 groups. A day was fixed to organize the Jigsaw classroom. After one week, their post knowledge was assessed. There was a significant difference in the performance of the students on the self-administered questionnaire before and after the intervention. The posttest score was increased (21.62) than the pretest knowledge mean score of 10.48. The calculated paired t’ test at 0.05 level of significance was 3.76 which is greater than the table value of 1.684. Thus, the Jigsaw Learning method proved to be an effective educational learning tool for nursing students.
A Study to Evaluate the Effectiveness of Planned Teaching Programme on Knowledge regarding First Aid Management among Primary School Teachers in selected schools at Bangalore
Authors: Keshavrao Tupe Bharati
Published: October 2023

First aid is the first and immediate assistance given to any children with either a minor or serious illness or injury, with care provided to preserve life. The results of study showed that pre-test mean score is 15.65 with 48.9% with standard deviation of 3.862 before the administration of planned teaching programs, the post-test mean score is 25.75 with 80.46%. The comparison of overall knowledge scores on first aid management before and after the planned teaching programs. The mean difference 10.10 with standard deviation 3.549 the t-test value t = 25.452 and is significant. In all aspects the school teachers have improved their knowledge after the administration of planned teaching programs. The difference between pre-test and post-test knowledge score is large it is significant. Statistical significant was calculated using students paired t-test. The association between selected demographic variables significantly associated with the pretest knowledge scores. The association was determined by using Pearson chi square test.
Spravato (Esketamine)
Authors: V. Nirosha , V. Gayathri
Published: October 2023

Depression is more than feeling a little sad or "blue" for a few days. Antidepressant medications are used in the treatment of clinical depression, usually alongside other forms of therapy such as psychological or behavioral therapy. Spravato is a medicine used to treat adults with major depression that is resistant to treatment. (Bahr, 2019) It is used in combination with an SSRI or SNRI medicine (other antidepressants) when at least two other treatments have failed. Spravato contains the active substance esketamine.
Stress among Nursing officers during Covid-19 in Govt Medical College Hospital, Thiruvananthapuram
Authors: Hari Krishna G L , Biji Rani E , Bismina Muneer , Christeena Santhosh , Devu C S , Drushya Sadeeswaran , Gayathri Suresh , Janeesha S , Jayalekshmi J , Jeny Shaji
Published: October 2023

Nursing officers caring Covid-19 patients are experiencing mental and emotional distress during duty time. Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. Stress can be defined as any type of change that causes physical, emotional, or psychological strain. Stress is your body's response to anything that requires attention or action. Everyone experiences stress to some degree. Healthcare workers, particularly nurses, are at risk for developing psychological distress as a result of direct contact with patients and the increasing work demand during the pandemic. The objective of this study was to assess the stress among Nursing officers during Covid -19 in Government Medical College Hospital, Thiruvananthapuram. Non experimental descriptive design was used. A sample of 140 nursing officers were recruited using convenience sampling technique. Data was collected using Socio personal data sheet and a standardized scale, Perceived Stress Scale by Cohen. The scale consists of 10 items with score ranging from 0 to 40. The study was conducted after getting IRC and IEC clearance and informed consent was obtained from study participants. More than half of nurses surveyed were belonged to the age group of 31-40 years (56.4%) with female nurses constituting 83%. Nearly half of the samples were BSc Nursing degree holders (46.4%). More than half of the samples (51.4%) are having an experience between one and five years. The study has found that 76% of the study participants has moderate stress, where as 12% are having mild stress and 12% are having severe stress. The present study showed a significant relationship between stress among nursing officers during Covid -19 and in service training on care of patients with Covid -19. The findings of the study showed the need for stress reduction programmes for nursing officers and ongoing in service training on Covid -19 care.
Effectiveness of information videos regarding autism among primary school teachers at selected rural schools of Bangalore
Authors: N Vanitha
Published: October 2023

Autism is a developmental disorder which is characterized by a qualitative alteration of social interaction, communication and repetitive behaviors, interest and activity. Early identification of autism will improve the health and well-being of the children and prevents the possible disabilities which might occur in future. The objective of the study is to assess the existing level of knowledge regarding autism among primary school teachers; to determine the effectiveness of information videos to enhance knowledge of primary school teachers regarding autism and to find association between knowledge of primary school teachers with selected socio demographic variables. One group pretest –posttest design was selected for the study. Structured knowledge questionnaire was used to collect data from 60 primary school teachers in rural school of Bangalore. Samples were selected using non probability convenient sampling technique. The obtained data were analyzed using descriptive and inferential statistics and interpreted in terms of objectives and hypotheses of the study. The level of significance was set at 0.05 level.: In the pre-test, about 63.3% of the samples had inadequate knowledge where as in the post test of the samples (66.7%) had gained adequate knowledge. These findings indicate that the video assisted teaching programme was effective in enhancing the knowledge of the primary school teachers regarding autism. A significant association was found between age (χ2 = 4.32), marital status (χ2=3.95) and place of residence (χ2=5.48) and the mean pre-test knowledge scores at 0.05 level of significance.
A Study to assess the effectiveness of Planned Teaching Program on knowledge regarding Congenital Heart Disease among Eligible couples in selected area of Mehsana city
Authors: V. Patidar Jayesh , Parmar Mitaraj
Published: October 2023

Introduction: Birth defect result in abnormal physiology, often with detrimental consequences, be it physical, developmental or intellectual disability. Congenital heart disease is non-specific medical term for range of defect present at the time of birth. Congenital heart disease can arise from combination of genetic and environmental cause.1design: A quantitative approach using pre-experimental one group pre-test post-test research design. Participants: 60 selected eligible couple of Mehsana city using non-probability convenience sampling technique. Tool: self-structured knowledge questionnaire. Result: with regards to pre-test level of knowledge it shows that, maximum 48(80%) participants were having poor knowledge, 12(20%) participants were having average knowledge. during post-test maximum 35(58.3%) of participants were having good knowledge and remaining 25(41.7%) of participants were had average knowledge. In pre-test, participants mean was 5.25, with standard deviation 1.80. in post-test participants mean was 13.81, with standard deviation 1.99. Conclusion: there was an increase knowledge score after planned teaching programme. There is significant moderate co-relation between the knowledge of the eligible couples regarding congenital heart disease.
A descriptive study to assess the knowledge and attitude regarding birth spacing and use of IUCD as a temporary family planning method among the married women of selected rural area of Byahatti PHC, Dharwad district with a view to develop informational booklet
Authors: Kumbar Basavva , H. Bhatakhande Asha , Kadam Shruti
Published: October 2023

Human fertility is determined by several factors like age at marriage, customs, education, etc. In India, reproductive age group women are more than 248 million. Therefore, Government of India introduced several policies on family planning and recognized the importance of contraception. Intrauterine contraceptive devices (IUCDs) have been successfully used by Indian women; however, still there are some disbeliefs and misconceptions regarding its usage and also Birth Spacing is very important in child growth and development. A descriptive study was conducted among 60 married womens of selected rural area of Hubballi. The samples were selected using Non-Probability; Purposive Sampling Technique. Data was collected by interview schedule and attitude scale. Data analysis was done using descriptive and inferential statistics. Overall results of the study revealed that out of 60 subjects, 13 (22%) had good knowledge, 38 (63%) had average knowledge, and 9 (15%) had poor knowledge regarding birth spacing and use of IUCD as a temporary family planning method. In terms of attitude 14 (23%) had positive attitude, 42 (70%) had neutral attitude, and 04 (7%) had negative attitude towards birth spacing and use of IUCD as a temporary family planning method.
Effectiveness of Structured Teaching Programme on Knowledge regarding Hazards of Plastic use among women between 20 to 50 years in a selected area in Thiruvalla Municipality
Authors: Babu Arya , Nadeshan Megha , SIC Mayukha , Jacob Vineetha
Published: October 2023

The present study was aimed at finding the effectiveness of STP on knowledge regarding hazards of plastic use. The research approach used for the study was quantitative and research design was one group pretest posttest pre experimental design. The tool used for the study was structured knowledge questionnaires and baseline proforma. Content validity of the tool and contents was obtained from subject expert. In the main study 30 women from between the age group 20-50 years are selected by non -probability convenient sampling. The pretest knowledge on hazards of plastic use was assessed using structured knowledge questionnaires and STP was given. The majority (43.3%) of the sample who participated were from the age group of 41 to 50 Years and above whereas the remaining (36.7%) were from the age group of 31 to 40 years and 20% of mothers were in the age group of 21 to 30 years. Post test was conducted using the same tool. The data was tabulated and analysed using descriptive and inferential statistics. The study was aimed to assess the effectiveness of STP on hazards of plastic use. The findings of the study revealed that there is an increase in knowledge of the women on hazards of plastic use. The study results revealed that STP was effective.
Effectiveness of Planned Health Teaching on Knowledge regarding Pregnancy Induced Hypertension among Antenatal Mothers in selected rural area
Authors: Shridhar Ghag Shweta , Gaikawad Vanita , Tomy Sara , Kumari Nutan , Naik Pournima
Published: October 2023

Hypertensive disorders of pregnancy are among the leading causes of maternal and perinatal deaths in developing countries. Hypertensive disorders of pregnancy rank high among the causes of maternal mortality and morbidity. Thus emphasizing the need to address this problem in order to ensure health and well-being of antenatal mothers. Methods: A pre experimental one group pre-test post-test study on effectiveness of planned health teaching on knowledge regarding pregnancy induced hypertension among antenatal mothers in selected rural area. Total 60 mothers were selected by method of Probability simple random sampling technique as per the inclusion criteria. Pre- test was conducted to assess the knowledge of antenatal mothers regarding pregnancy induced hypertension using structured knowledge questionnaire on day ‘1’. On the same day planned health teaching was also administered to antenatal mothers regarding pregnancy induced hypertension. On 7th day Post-test was conducted to assess the gain in knowledge using the same planned health teaching on the same sample. Finding: The pre-test mean score was 5.25 and the post-test mean score was 13.65. Thus there was significant difference between pre-test and post-test knowledge. Paired ‘t’ test was applied and calculated t value is 15.56 at 59 degree of freedom which is higher than the tabulated value 7.45 at 5% level of significance. Hence it was statistically interpreted that planned health teaching on pregnancy induced hypertension was effective. There was significant association of post-test knowledge with selected demographic variables that is age, Education and occupation as chi-square value is 13.52 and 14.20 respectively higher than the table value at 5% of significance which was statistically accepted. Hence it can be concluded that the study concluded that the planned health teaching as effective in improving the knowledge of antenatal mothers regarding pregnancy induced hypertension.
Into the Mystery
Authors: Mecheva Marina L.
Published: October 2023

Can we gain spiritual knowledge by tuning into the body’s inherent wisdom? This paper explores such a possibility through the lens of Embodied Spiritual Inquiry (ESI), a participatory approach to transpersonal learning, developed by Jorge N. Ferrer, proposing the integration of multiple ways of knowing through physical, somatic, vital, emotional, mental and spiritual experiences. The focus of this phenomenological study was on the experience of ESI and its potential transformative value for inquirers. Seven individuals who previously participated in ESI research were interviewed. Findings emerged through eight essential themes: four textural constituents - transpersonal experiences, intimacy with self and others, transformation in everyday life, and serendipity; and four structural qualities - inquiry container, intuitive knowing through the body, collaborative research, and enhancement of other practices. Results reflected the intrapersonal, interpersonal and transpersonal experiences of participants, suggesting that ESI may have a transformative value for researchers engaging with the method. While these results require further investigation in regard to their transferability, they may inspire future studies in light of the implications of transpersonal research in the field of psychology and beyond.
Perspective-Taking and Perspective-Sharing in Pediatric Education: Exploring Connections Between Strategies of Medical Students and Patients’ Caregivers
Authors: Eijkelboom M. C. L. , De Kleijn R. A. M. , Baten L. , Frenkel J. , Van der Schaaf M. F.
Published: October 2023

Introduction: In pediatric education, caregivers are increasingly involved to share their perspective. Yet, an in-depth understanding of the perspective-taking process between medical students and caregivers is lacking. This study explored: 1) Which strategies do medical students use to take a caregiver’s perspective and which facilitators and constraints do they perceive? 2) Which strategies do caregivers use to share their perspective with students? and 3) How do students’ perspective-taking strategies relate to caregivers’ perspective-sharing strategies?
Methods: In an online lesson: two caregivers of pediatric patients, shared their story with 27 fourth-year Dutch medical students. After the session, students undertook an assignment where they individually reflected on how they took perspective. Students’ reflections were collected via audio recordings. Caregivers were individually interviewed. Data were analyzed through thematic and cross-case analysis.
Results: Students used eight perspective-taking strategies, in various combinations. Students used inferential strategies, where they made inferences from available information, and cultivating strategies, where they attempted to elicit more information about the caregiver. Students perceived individual-, contextual- and caregiver-related facilitators and constraints for taking perspective. Caregivers shared their perspective by adopting multiple strategies to share their story and create a trusting learning environment. We visualized connections between students’ perspective-taking strategies, facilitators/constraints, and caregivers’ perspective-sharing strategies.
Discussion: By combining data from both perspective-takers (students) and perspective-sharers (caregivers), this study provides a foundation for future research to study perspective-taking between students and patients in an educational context. On a practical level, our findings provide tools for students, patients, and educators to enhance perspective-taking processes.
A percepção dos professores de apoio das escolas do campo sobre educação inclusiva e a adoção de sistemas de software inclusivos
Authors: Silva Isabela da , Xavier Cristiane Batista , Oliveira Roberto Felício , Oliveira Givanilde de Assis dos Santos , Stacheira Claudio Roberto
Published: October 2023

O estudo investiga as percepções dos professores de apoio sobre a educação inclusiva e a implementação de Sistemas de Software Inclusivos em escolas rurais. O estudo utilizou um questionário online para coleta de informações dos professores de apoio em escolas rurais. Os resultados demonstram estratégias para promover a educação inclusiva, incluindo a adoção de Sistemas de Software Inclusivos. Como solução, sugere-se a criação de projetos de extensão e programas acadêmicos focados na educação inclusiva, oferecidos por Instituições de Ensino Superior.
أثر المخصصات الفنية على العبء الضريبي لشركات التأمين في فلسطين
Authors: أسمر معاذ , الحاج طارق , خلوف مصطفى
Published: October 2023

هدفت هذه الدراسة التعرف على إثر المخصصات الفنية على العبء الضريبي في شركات التأمين في فلسطين، واستخدمت الدراسة المنهج الوصفي التحليلي وتم جمع بيانات شركات التأمين العاملة في فلسطين من هيئة سوق رأس المال الفلسطيني ما بين الاعوام (2012-2021)، وتم استخدام نموذج الانحدار الخطي في اختبار فرضيات الدراسة.  وتوصلت الدراسة الى عدة نتائج كان اهمها ان شركات التأمين تستفيد من المخصصات الفنية في تخفيض مقدار العبء الضريبي عليها، وانه يوجد أثر للمخصصات الفنية ( مخصص تعويضات تحت التسوية، مخصص الاخطار السارية) على العبء الضريبي (ضريبة الدخل، ضريبة القيمة المضافة) في شركات التأمين المدرجة في بورصة فلسطين، ومن أهم التوصيات اعادة النظر في تكوين المخصصات الفنية في شركات التأمين العاملة في فلسطين لتتزايد حسب حجم الاقساط المكتتبة وليس حسب مرور الزمن، وزيادة الرقابة من قبل مكاتب ضريبة الدخل على شركات التأمين فيما يخص طرق احتساب المخصصات الفنية, والاستمرار في تعزيز الاحتياطات الفنية الى جانب تعزيز الضوابط الفنية للاكتتاب.
الكلمات المفتاحية: العبء الضريبي، المخصصات الفنية، مخصص الاخطار السارية، مخصص الادعاءات تحت التسوية, شركات التأمين
Management and Marketing of Circulation of First-Line Antituberculosis Medicines: Use of Innovative Research Technologies
Authors: Osyntseva Alina , Shapovalov Valentyn
Published: October 2023

The management and marketing of first-line antituberculosis medicines are paramount for the effective containment and treatment of tuberculosis, a global health challenge. Ensuring the optimal circulation of these medicines requires a seamless integration of supply chain management, demand forecasting, and strategic marketing. The introduction of innovative research technologies has transformed the landscape, offering enhanced methods for drug distribution, patient adherence, and efficacy tracking. Digital platforms harness data analytics to predict medicine demand more accurately, ensuring timely production and distribution, minimizing wastage, and optimizing resource allocation. Furthermore, innovative technologies such as blockchain can fortify the drug supply chain against counterfeits, ensuring that only genuine products reach end-users. On the marketing front, artificial intelligence-driven tools enable targeted awareness campaigns, providing personalized patient information and improving adherence to drug regimens. As tuberculosis treatment necessitates prolonged medication courses, ensuring patient compliance is crucial. Advanced research technologies assist in real-time monitoring of patient's drug intake, identifying potential drop-offs, and intervening timely. The main principles of pharmacotherapy of tuberculosis were presented in the article. Pharmaceutical marketing of anti-tuberculosis drugs was experimentally researched. The most promising manufacturers in terms of availability, quality, and demand for doctors, pharmacists, and patients were highlighted. In summary, innovative research technologies are indispensable in the modern management and marketing strategies of first-line antituberculosis medicines, fostering improved treatment outcomes, patient safety, and global tuberculosis containment efforts.
Le riviste di Umberto Notari (1903-1922): cultura visiva a Milano tra Futurismo e Novecento
Authors: Castellani Carlotta
Published: October 2023

Obiettivo del contributo è delineare l’attività editoriale di Umberto Notari, poco studiata dalla critica, analizzando alcune riviste fondate a Milano tra 1903 e 1917: il «Verde e Azzurro», «La Giovane Italia», «Gli Avvenimenti» e «Le Industrie Italiane Illustrate». Oltre a rintracciare le collaborazioni con i membri del Futurismo e del gruppo di Novecento, l’analisi di questi periodici mostra in che misura Notari si sia servito delle sue riviste per elaborare pionieristiche strategie pubblicitarie, di comunicazione di massa e di organizzazione del consenso, che hanno avuto molti riflessi nella cultura visiva a lui contemporanea.
La linea dell’orizzonte dell’ethnographic novel tra scrittura autobiografica e Bildungsroman
Authors: Mazzola Arianna
Published: October 2023

Il contributo si propone di indagare lo scandaglio euristico di un mezzo espressivo sempre più frequentato, il graphic novel. In ragione di ciò, analizzare l’ibridazione tra parola e immagine da un lato rispetto all’immediatezza del disegno, dall’altro in relazione al grado di approfondimento psicologico dei personaggi, permette di mettere in luce la possibilità di considerare il romanzo a fumetti come un genere letterario in dialogo con la più classica forma narrativa. Dunque, privilegiare un lavoro di stampo metodologico-teorico può porre delle premesse adeguate a una successiva focalizzazione su un caso di studio. In particolare, «La linea dell’orizzonte». Un ethnographic novel sulla migrazione tra Bangladesh, Italia e Londra dialoga non soltanto con la forma romanzo in generale, ma anche con il reportage narrativo, l’autobiografia e il Bildungsroman, o romanzo di formazione. È evidente che questo stretto dialogo con la critica letteraria non possa non prendere in considerazione, oltre a uno studio dei generi letterari maggiormente in dialogo con La linea dell’orizzonte, anche un’analisi delle peculiarità stilistiche e tematiche presenti nell’ethnographic novel, con particolare attenzione al tema della migrazione.
PREVALENCE, RISK FACTORS, MANAGEMENT, OUTCOMES, AND PREDICTORS OF MORTALITY IN RETROPERITONEAL HEMATOMA AFTER PERCUTANEOUS CORONARY INTERVENTION
Authors: SAOOD Y , ASIM M , SALMAN A , KHAN MI , ZAFAR R , KAZMI SIA
Published: October 2023

The development of complications related to femoral artery puncture continues to be frequent following contemporary percutaneous coronary intervention (PCI). The basic aim of the study is to find retroperitoneal hematoma after percutaneous coronary intervention prevalence, risk factors, management, outcomes, and predictors of mortality. This retrospective cohort study was conducted at the Peshawar Institute of Cardiology, Peshawar, from January 2022 to April 2023. The study population consisted of patients who underwent PCI procedures. Sixty-eight patients who developed RPH after PCI were included in the analysis. Demographic information such as age, gender, and relevant baseline characteristics of the patients was recorded. Clinical variables encompassed comorbidities (e.g., hypertension, diabetes mellitus), the indication for PCI (e.g., stable angina, acute coronary syndrome), and procedural details, including the access site and anticoagulant medications. Data was collected from 68 patients. The mean age of patients who developed RPH was 63.7 years, ranging from 45 to 78 years. Gender distribution showed 60% male and 40% female patients. Common comorbidities among this cohort included hypertension (80% of cases) and diabetes mellitus (45% of cases). The study identified several risk factors associated with the development of RPH post-PCI, including female gender (p < 0.05), anticoagulant use (p < 0.01), and hypertension (p < 0.05), which demonstrated a statistically significant association. Based on the results, the study provides valuable insights into the prevalence, risk factors, management strategies, clinical outcomes, and predictors of mortality associated with RPH following PCI.
IMPACT OF BACTERIAL INFECTIONS IN PERITONEAL DIALYSIS PATIENTS
Authors: NAJUMUSAQIB M , ZAINAB . , ULLAH H , SALMAN A , SABEREEN M , BANARAS F
Published: October 2023

Bacterial infections can cause significant clinical complications in patients undergoing Peritoneal Dialysis (PD). This study aimed to determine bacterial infection's clinical and psychosocial outcomes in PD patients. A prospective observational study enrolled 150 PD patients through non-probability sequential sampling. Demographic information, duration of PD, previous infections, and laboratory results were collected. Bacterial infections were identified through routine cultures of PD fluids, and antibiotic susceptibility was determined using the disc diffusion method. The average age of PD patients was 52.3 years, with 42% men and 58% women (p<0.05). Staphylococcus aureus infected 22 patients (14.67%), whereas Streptococci infected 18 patients (12%) (p<0.05). Antibiotic susceptibility assays determined that Staphylococcus aureus was 77% sensitive to vancomycin. Seventy-five patients (50%) on PD for more than 19 months encountered infections. Among the infected group, 90 patients (60%) recovered without complications, while 5 (4.2%) died. The study revealed a significant correlation between bacterial infections in PD patients and clinical symptoms, antibiotic resistance patterns, and disease duration. These findings highlight the importance of enhanced patient monitoring and evolving treatment strategies to improve patient outcomes.
Solving Quantitative Problems in Finance: A Tool for Unlimited Practice
Authors: Keen Howard
Published: October 2023

Students are continuously told that the way to learn finance is to “do finance” which means to practice solving quantitative problems. For this recommendation to work, however, it requires students to have a tool that allows them ample opportunities to practice. This paper presents such a tool and one that instructors can easily create as well as customize to their own way of presenting topics. Moreover, with pressure to keep costs for students down, this tool requires no subscription to any commercially available product. Although this tool has been developed to include many standard finance topics, this paper illustrates the use of the tool for various aspects of the “Time Value of Money” topic. The paper includes a description of how the tool has been applied in an introductory corporate finance course.
Avian Trichomoniasis Prevalence in Domesticated Pigeons in Thi-Qar Province, Iraq
Authors: Jaafar Ahmed
Published: October 2023

Abstract |  Avian trichomoniasis is a disease that is spread globally in wild and domesticated birds, especially pigeons, caused by the parasite Trichomonas gallinae and known as canker. The complications of this illness include lesions in the upper gastrointestinal tract. The present study's goal would be to study the prevalence of T. gallinae in domesticated pigeons in Thi-Qar province, Iraq, utilizing the internal transcribed spacer1-5.8s rRNA-internal transcribed spacer2 gene. A total of 405 pigeons including 160 of Alzajil pigeons, 160 of red pigeons and 85 of Arafali pigeons were collected from local markets for the period from September 2022 to May 2023, the infection rates were 38.13, 37.50, and 42.35 respectively. The study noted a non-significant difference at p. value < 0.05 in distribution of T. gallinae according to bird's species. The study found that infection rate is higher in squabs than adults in all pigeons of the three groups. There was no effect of sex on the prevalence rates. As for the months in which the samples were collected the study found there is  significant difference at p. value < 0.05 of parasite distribution according to collection months, the highest infection rate was recorded in November 68.89 while the lowest isolated parasite was in April 17.78.     

Key words | Thi-Qar province, avian trichomoniasis, pigeons, light microscope.
A fibered Tukia theorem for nilpotent Lie groups
Authors: Dymarz Tullia , Fisher David , Xie Xiangdong
Published: October 2023

We establish a Tukia-type theorem for uniform quasiconformal groups of a Carnot group. More generally we establish a fiber bundle version (or foliated version) of Tukia theorem for uniform quasiconformal groups of a nilpotent Lie group whose Lie algebra admits a diagonalizable derivation with positive eigenvalues. These results have applications to quasi-isometric rigidity of solvable groups [DFX].
Distal Femur Valgus Deformity After Rigid Intramedullary Nailing of Adolescent Femoral Shaft Fracture
Authors: Burton Michael G. , Moon John Y. , Roberts David W.
Published: October 2023

A 12-year-old girl developed a distal femoral shaft fracture treated with lateral trochanteric entry intramedullary nail fixation. The nail was retained after union because of a persistent nonossifying fibroma at the previous fracture site. At 16 months after surgery, marked valgus deformity was noted at the distal femur, with signs of implant haloing and loosening, suggesting repetitive motion and stress concentration of forces at the distal femur. Owing to recognition before skeletal maturity, the valgus was corrected with hemiepiphysiodesis. This finding illustrates the importance of follow-up up to skeletal maturity for pediatric femoral shaft fractures and consideration of routine removal of implants after fracture union to avoid this previously unreported complication.
L’odorat chez Rabelais
Authors: Ternaux Jean-Claude
Published: October 2023

En tant que médecin, Rabelais est habitué à sentir et cet usage de l’odorat se retrouve dans ses romans. La perception olfactive est également un ressort fictionnel particulièrement attaché au personnage de Panurge. Ainsi, Gargantua, Pantagruel, le Tiers livre et le Quart Livre sont traversés de mauvaises odeurs, toutes signifiantes. Quant aux bonnes odeurs, leur présence est davantage associée aux ouvrages des humanistes, qui « fleurent bon ».
Représenter les sens en scène, xive-xvie siècles
Authors: Devlaeminck Marielle
Published: October 2023

Le théâtre est avant toute chose un média audio-visuel de masse à l’époque nous occupant. Il n’est, dès lors, pas surprenant que les sens qui soient les plus difficiles à y représenter soient précisément le toucher, le goût et l’odorat. Par le recours à des topoï littéraires et aux personnages allégoriques, toutefois, les auteurs médiévaux on put mettre en scène à la fois ces trois sens et les discours moraux et sociaux les entourant.
Les parlers romans dans l’atlas sonore des langues et dialectes de Belgique
Authors: Boula de Mareüil Philippe , Mahin Lucien , Vernier Frédéric
Published: October 2023

Nous décrivons ici un atlas linguistique sonore qui prend la forme d’un site web présentant une carte interactive de Belgique, où l’on peut cliquer sur une cinquantaine de points d’enquête pour écouter et lire une même histoire en langues régionales endogènes (romanes et germaniques). Nous avons enregistré la fable d’Ésope « La bise et le soleil » (utilisée par l’Association phonétique internationale pour illustrer nombre de langues du monde) dans le but de mettre en valeur la richesse du picard et du wallon, en particulier.
What comes to count as sustainable in Rosendal? : a study of how sustainability is being reproduced in an urban sociomaterial assemblage
Authors: Bäckman Malin
Published: October 2023

Urban districts around the world are increasingly developed to be sustainable. In this thesis I explore what comes to count as sustainable in Rosendal, a developing urban district in Uppsala, Sweden. I view Rosendal as an example of contemporary urban sustainability. In light of how urban sustainability initiatives tend to reproduce the status quo, my aim is to question taken-for-granted meanings of sustainability and open up for alternative perspectives. I explore which everyday practices residents of Rosendal associate with sustainability, by drawing upon practice-theoretical approaches. Additionally, I analyse the Sustainability in Rosendal discourse by focusing on the perspectives of Uppsala Municipality and property developers. I approach Rosendal as an urban sociomaterial assemblage, constantly in the process of being made. This perspective helps account for the various practices, discourses and ‘more-than-humans’ shaping what comes to count as sustainable, while decentring humans and bringing forth human interdependency with ‘the environment’. Additionally, the emergent character of assemblages points towards the possibility for urban environments to be developed differently. My findings show that prevailing sustainability meanings reproduced within practices and discourses, do not initiate the type of transformation often called for. Much of what currently comes to count as sustainable in Rosendal is underpinned by a neoliberal growth logic where attractive districts are developed for the chosen few. I show how more-than-human actants, including allotments, cars and wooden panels, contribute to what comes to count as sustainable in Rosendal. By paying attention to the effects of these actants, I envision alternative trajectories for the urban assemblages making up Rosendal. Finally, I suggest that integrating feminist care ethics into urban development can foster more just and transformative sustainabilities.
Pengaruh Nilai yang Dirasakan Terhadap Niat Pembelian Kembali Pelanggan Toyota : “Kepuasan Pelanggan Sebagai Variabel Mediasi”
Authors: Ibrahim Ibrahim
Published: October 2023

Persaingan yang semakin ketat dalam pasar mobil, dimana konsumen dihadapkan pada berbagai alternatif pilihan produk yang ditawarkan, maka produsen dituntut untuk selalu mengikuti perkembangan pasar sebagai dasar penetapan keputusan terhadap strategi pemasaran perusahaan. Saat ini kualitas produk serta nilai yang dirasakan adalah permasalahan terpenting dari pembeda antara dealer mobil satu dengan dealer mobil yang lain. Hanya dealer mobil yang memberikan kualitas produk dan fasilitas nilai yang dirasakan, untuk dapat mempunyai pelanggan yang loyal terhadap dealer. Tujuan penelitian ini adalah untuk mengetahui apakah ada pengaruh antara nilai yang dirasakan terhadap niat pembelian kembali produk toyota di Pidie melalui variabel kepuasan pelanggan sebagai variabel mediasi. Objek penelitian ini adalah pelanggan produk toyota. Metode yang digunakan dalam penelitian ini adalah metode purposive sampling. Sedangkan teknik analisis data yang digunakan adalah analisis jalur. Hasil penelitian menunjukan bahwa variabel kepuasan pelanggan sebagai variabel mediasi berpengaruh secara langsung terhadap variabel niat pembelian kembali dari nilai yang dirasakan oleh pelanggan produk toyoda di Pidie dengan pengaruh yang signifikan. hal ini dikarenakan nilai koefisien hubungan langsungnya lebih besar dari pada nilai koefisien tidak langsung yang berarti nilai yang dirasakan berpengaruh terhadap niat pembelian kembali secara tidak langsung melalui kepuasan pelanggan.Terjadi mediasi parsial karena pengaruh variabel independen pada variabel dependen baik secara langsung maupun tidak langsung adalah signifikan.
Peran Tuha Peut Gampong sebagai Mediator dalam Penyelesaian Sengketa Harta Warisan
Authors: Siti Zalikha  , Apriani
Published: October 2023

Tuha peut Gampong adalah unsur pemerintahan Gampong yang berfungsi sebagai badan permusyawarahan Gampong, tuha peut juga merupakan tokoh lembaga adat yang menyelesaikan persengketaan masyarakat, salah satunya yaitu penyelesaian harta warisan. Dalam hal ini tuha peut hanya mediator yang mencoba membantu mendamaikan dan menyelesaikan perkara bukan untuk memutuskan. Adapun permasalahan yang ingin diteliti adalah bagaimana peran tuha peut Gampong sebagai mediator dalam penyelesaian sengketa harta warisan di Gampong Neubok Badeuk Kecamatan Tangse Kabupaten Pidie. Metode yang digunakan dalam penelitian ini adalah metode kualitatif, karena metode tersebut dapat menjelaskan fenomena masyarakat yang diteliti.Sedangkan untuk mengungkapkan gejala yang ada dalam masyarakat, peneliti menggunakan pendekatan deskriptif untuk memberikan gambaran tentang peran tuha peut Gampong dalam menyelesaikan sengketa. Dalam hal ini penulis menggunakan sumber data primer yaitu anggota tuha peut Gampong. Penulis juga menggunakan dokumen dan referensi lainnya yang relevan. Sedangkan tehnik pengumpulan data yang digunakan adalah observasi dan wawancara. Hasil penelitian menunjukkan bahwa disaat persengketaan warisan terjadi pada masyarakat, satu-satunya jalan adalah mencari sosok mediator yang bijaksana dan mampu dalam sengketa yang dihadapi masyarakat, kebiasaan yang telah terjadi sengketa masyarakat selesai di tangan tuha peut yang mana dalam memproses perkara, tuha peut tidak membenarkan satu pihak dan menyalahkan pihak yang lain, dalam proses perdamaian, tuha peut mencoba semaksimal mungkin untuk menyatukan hubungan kekeluargaan yang sempat hancur karena persoalan harta. Penyelesaian yang dilakukan oleh tuha peut Gampong yaitu menggunakan prinsip kebijaksanaan antara ahli waris dengan persetujuan ahli waris itu sendiri. Demi menjaga kerukunan dan persaudaraan antara para pihak yang bersengketa.
Penerapan Mashlahah Al-Mursalah Dalam Kitab Ahwâl Al-Syakhsiyyah Karya Muhammad Abû Zahrah
Authors: Kasdim Bustami
Published: October 2023

This research is motivated by the verses of the Qur’an and the Hadits as source of Islamic law that is limited in preparing a problem, while the problem continues to develop and unlimited in accordance with the times. Therefore, there is a need for legal arguments to solve problems that have no arguments in the Qur’an and Hadits. Among the arguments used in addition to the Qur’an and the Hadits are: Ijmâ, Qiyâs, Istihsân, Mashlahah Mursalah, ‘Urf, Syar’u man Qablanâ, Qawl al-Shahâbî, Istishâb, and Sad al-Dzarî’ah. This needs to be emphasized that the main problem was used as the object of this research focused on the concept of al-Mashlahah al-Mursalah according to Muhammad Abû Zahrah as the argument for establishing the law and its application in his book al-Ahwâl al-Syakhsiyyah. Then the questions in study are: How the Application of the Concept of al-Mashlahah al-Mursalah in the Kitab al-Ahwâl al-Syakhsiyyah by Muhammad Abû Zahrah concerning Family Law? This type of research is literature research (library research) while the data source is from books of fiqh and ushûl fiqh. The type of data is qualitative. The object of research is the Concept of al-Mashlahah al-Mursalah and its application in book of Muhammad Abû Zahrah. Data collection is done through literature studies of the main books plus other texts of analysis, data analysis using content analysis, while the presentation of the data is done in descriptive analysis. This study produces several conclusions, namely: (1) the essence of al-Mashlahah al-Mursalah made by Muhammad Abû Zahrah as a proposition in Islamic Shari’ah is al-Mashlahah al-Mursalah which is in accordance with the objectives af Shari’ah, namely: al-Muhafdzah ‘alad Dîn (nurturing religion), al-Muhafadzah ‘ala al-Nafs, (nurturing the soul), al-Muhafadzah ‘alal ‘Aql (nurturing reason), al-Muhafadzah ‘alan Nasl, (maintaining descent) and al-Muhafadzah ‘alal Mâl, (maintening property and objects). According to him, these 5 things should not be violated in any statutory regulations. Efforts to maintain these 5 things, Muhammad Abû Zahrah quoted the distribution of ushûl al-Fiqh scholars to him as 3 namely dharûriyyah, hajjîyyah and tahsinîyyah in the field of Family Law namely, (a) cancellation of marriage, (b) livelihood of post-divorce children, (c) limitation of hadhanah period, (d) child nasab recognition with pledge.