bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalência de Doenças Parasitárias de Potencial Zoonótico em Cães Residentes em Leopoldina, Minas Gerais
Authors: Amaral Lacerda da Silva Verônnica
Published: November 2020

Os animais são transmissores de vários parasitos que podem ocasionar doenças conhecidas como zoonóticas, podendo causar grande impacto na vida dos seres humanos e na vida do próprio animal com muitos prejuízos a ambos. Assim, este trabalho objetivou verificar a prevalência das principais doenças parasitárias com potencial zoonótico na região de Leopoldina, cidade situada no interior do Estado de Minas Gerais. Trata-se de um estudo descritivo, retrospectivo, realizado em um laboratório veterinário particular no período de janeiro a dezembro de 2017. Neste estudo, foram analisadas 109 amostras de fezes de cães das quais 57 foram positivas para alguma parasitose. Das amostras investigadas, 38 evidenciaram infecções únicas e 19 infecções múltiplas. Foram identificados 23 helmintos e 57 protozoários, totalizando 80 diferentes espécies, destas 29 foram de Giardia sp, 28 foram de Isospora canis, 16 de Ancylostoma sp, quatro de Strongyloides stecoralis uma de Toxocara canis, uma de Taeniidae e uma de Uncinaria sp. As análises revelaram a presença de parasitas de potencial zoonótico, sendo esses Giardia sp, seguida por Ancylostoma sp, Strongiloides stecoralis e Uncinaria sp. Com esses resultados se pode concluir a necessária importância de medidas de prevenção primária a saúde para devida conscientização da população e profissionais veterinários e de saúde qualificados para que possam auxiliar no diagnóstico e, consequentemente, na redução do índice dessas parasitoses e na causa de doenças debilitantes aos humanos e animais.
Fístula Dentária Infraorbitária em Cão
Authors: Rodrigues Perin Rayzza , Yoshioka De Vidis Natália , Barriento de Azambuja Munir , Vieira Antunes Junior Henrique Jorge , Anes de Souza Jaqueline
Published: November 2020

A fístula infraorbitária é uma afecção comum em cães que acomete, geralmente, o quarto dente pré-molar superior, o único que possui três raízes, também denominado popularmente como “dente carniceiro”, em função de suas funções de auxílio na caça e trituração de alimentos sólidos. As causas dessa enfermidade incluem traumas, fraturas de coroa, doenças periodontais, neoplasias, entre outras. Tais afecções geram infecção bacteriana no ápice alveolar da raiz dentária, juntamente com inflamação intensa, levando à osteólise da cavidade nasal ao seio maxilar, gerando assim um abcesso periapical, infraorbitário, que é observado nos animais acometidos. O diagnóstico ocorre, principalmente, por meio de avaliação da cavidade oral do animal sedado e de radiografia intraoral identificando áreas de radioluscência em torno do ápice da raiz acometida, evidenciando assim a osteólise e infecção bacteriana. A exodontia nem sempre é o tratamento indicado, pelo menos inicialmente. O caso relatado neste artigo é de uma paciente canina adulta diagnosticada com fístula infraorbitária, a qual passou por tratamento conservador e, apresentando recidiva, foi encaminhada para exodontia, sendo considerado bom prognóstico do quadro clínico no pós-cirúrgico e recuperação total após tratamento. Este trabalho tem como objetivo discorrer sobre essa afecção e elucidar, por meio de revisões bibliográficas, sobre as indicações de tratamento conservador, endodontia ou exodontia, facilitando assim a abordagem clínica diante dos casos.
Aspectos de Biossegurança Com Enfoque em Fonoaudiologia: Revisão de Literatura
Authors: Laurindo Porto Andrea Cintia , Justino Gomes Rayane , Da Costa Silva Tayná Maríllia , Estrela Barbosa Priscilla Mayara , Sampaio Sousa Caroline , De Farias Marques Francisca Jakelyne
Published: November 2020

A Biossegurança é de extrema importância para qualquer tipo de trabalhador na execução de seu ofício. Para os profissionais da saúde, além de proporcionar tal direito ao paciente, as condutas em Biossegurança erradicam as possíveis formas de contaminação cruzada durante os atendimentos. O objetivo deste trabalho é proporcionar o esclarecimento sobre Biossegurança na Fonoaudiologia, sobretudo, para profissionais já atuantes e para auxiliar estudantes da área. A metodologias utilizada foi a revisão de literatura, na base de dados Scielo, Lilacs e Google Acadêmico, com base nos Descritores em Ciência e Saúde: biossegurança, contaminação, fonoaudiologia e saúde.  Os critérios de inclusão foram: artigos que abordassem a temática, em português, on-line, na íntegra, publicados de 2007 a 2017. A Fonoaudiologia, como um todo, tem que estar enquadrada dentro das normas de Biossegurança, já que os profissionais dessa área atuam em hospitais, atendimentos domiciliares e ambulatoriais, nos quais  há sempre contato físico com os seus pacientes. Assim, estes profissionais se tornam parte do grupo de risco de contaminação cruzada e o que se percebe é um descuido ou até mesmo um desconhecimento destes em relação a tais normas, por isso a urgência da propagação dos cuidados em Biossegurança.
Methods to Conduct a Health Impact Assessment Learning Collaborative
Authors: Stone Cynthia , Bochenek Andrea , Redenz Alison , Hansotte Elinor
Published: November 2020

Background: Indiana University Richard M. Fairbanks School of Public Health (IU FSPH) and the Health and Hospital Corporation of Marion County, through the Marion County Public Health Department (MCPHD), created a Health Impact Assessment (HIA) Learning Collaborative. The purpose of the HIA Learning Collaborative was to strengthen the capacity of both the academic and community partners to carry out HIAs. Entities recognize the value of creating a collaborative team to assure personnel are trained and available to provide time and expertise for plan reviews, formal feedback, data reports, literature summaries, and input in potential health/social impacts related to projects, which can ensure these impacts are considered in development work. In addition, the MCPHD and IU FSHP intend to increase HIA capacity in Indiana and remain committed to including health impact data into non-health sector decision making.
Methods: The group planned to meet monthly over the year with the following learning objectives. A survey was created in Survey Monkey in order to evaluate the overall HIA Learning Collaborative experience and to assess whether or not the learning objectives were met. The survey consisted of 11 questions: nine were multiple choice and two were open-ended.
Results: The majority of the objectives were met.
Conclusion: There is interest in conducting HIAs in the future and several ideas were generated.
İnovasyon ve Risk Alma Eğiliminin İşletme Performansına Etkisinde Uluslararası Faaliyette Bulunmanın Düzenleyici Rolü
Authors: ÜSTÜN Ferda , KOCA BALLI Ayşe İpek
Published: November 2020

Bu çalışmanın amacı, işletmelerin inovasyon ve risk alma eğilimlerinin işletme performansı ile ilişkisinde uluslararası faaliyette bulunmanın düzenleyici bir rol üstlenip üstlenmediğini belirlemektir. Araştırma, İstanbul Sanayi Odasının (İSO) “Türkiye’nin ikinci 500 Büyük Sanayi Kuruluşu” 2016 listesinde yer alan işletmeler üzerinde gerçekleştirilmiştir. Araştırma kapsamında işletmelerden elde edilen 849 anket kullanılmıştır. Araştırma sonuçlarına göre işletmelerin inovasyon ve risk alma eğilimleri işletme performansı üzerinde olumlu bir etkiye sahiptir. Bununla birlikte işletmelerin inovasyon eğilimleri ve risk alma davranışlarının işletme performansına etkisinde uluslararası olmanın, düzenleyici bir etkiye sahip olduğu görülmüştür.
A retrospective study on indications and histopathological analysis of non-oncological hysterectomies in a tertiary care hospital
Authors: Kasinathan Ananthi , Nagulapally Himabindu
Published: November 2020

Background: An increase in the number of women undergoing hysterectomy especially in South India is of great concern. Whenever hysterectomy is performed, it is imperative that clinical diagnosis is accurate. The purpose of current study is to assess whether the histopathological diagnosis after surgery is correlated with the clinical diagnosis. Methods: This is a retrospective study conducted in the department of obstetrics and gynaecology at Indira Gandhi medical college and research institute Puducherry, from January 2018 to December 2018. Patients, who underwent hysterectomy for benign causes, were included in the study. Data was collected from the patients' case records. Whether the histopathological diagnosis was in tandem with the clinical diagnosis, was notedResults: Out of the 234 hysterectomies performed, 46.15% were by abdominal route and 53.84% were by vaginal route. 24.7% were TAH with BSO with mean age of 49.72 years. VH with PFR (46.5%) was the most common surgery done. Out of the 80 cases of fibroid, 66 (28.2%) were confirmed on histopathology. Histopathological diagnosis corroborated the clinical diagnosis in patients with ovarian cyst, fibroid with ovarian cyst and DUB. Adenomyosis was validated in 7 of 9 cases. Endometriosis of ovary was confirmed in 4 (1.7%) cases. In patients with pelvic organ prolapse, histopathology showed atrophic changes.Conclusions: Accurate clinical diagnosis, supported by in-depth preoperative evaluation and a sound clinical knowledge helps to avoid unnecessary hysterectomies. It is imperative to study the histopathology of the operated specimen and confirm the appropriateness of the clinical indication.
Modelagem matemática aplicada no sistema Mandala: um estudo voltado para a produção sustentável
Authors: De Sousa Anderson Kerlly Rodrigues , Aureliano Vidal Francisco , Sueli de Sousa Maria
Published: November 2020

The main purpose of this study is to analyze the best way to build a Mandala garden system from the development of a consistent mathematical model. In this context, mathematical modeling is important since it seeks to maximize production in places with a low amount of available water. Thus, the following question is valid: what is the best way to analyze the productivity of Mandala garden beds that meet the requirements for income-generating in small rural communities? The research procedures used were based on the following methods: bibliographical review, descriptive, exploratory and quantitative data supplied from important scientific research projects to specify the mathematical modeling and types of crops to increase income-generating and productivity. Finally, this study will emphasize the results of the data obtained with the developed mathematical model and its possible contributions to the problem proposed in the research.
Caracterização química e atividades antioxidante e antifúngica do óleo essencial das flores de [Cochlospermum regium (Mart. ex Schrank.) Pilger] (Bixaceae)
Authors: Filho Antonio Carlos Pereira de Menezes , De Sousa Wendel Cruvinel , Castro Carlos Frederico De Souza
Published: November 2020

The objective of this work was to characterize the chemical and physicochemical profile, and the antioxidant and antifungal activities of the essential oil from Cochlospermum regium flowers. The flowers were collected in a riparian Cerrado area. The essential oil was extracted by hidrodestilation in Clevenger. The organoleptic parameters were evalueted for (color, visual and aroma), for physicochemical, yield (%), solubility, optical rotation (αD ), refractive index (20 °C) and density (25 °C g mL-1), antioxidant activity were determined by the reduction of free radical DPPH, and the antifungal activity was determined through the percentage of growth inhibition on Sclerotinia sclerotiorum, Colletotrichum gloeosporioides and Aspergillus flavus. The essential oil from C. regium flowers had an oily, clear, crystalline and strongly aromatic liquid, yield of 0.099%, positive solubility, optical rotation +36.1 αD , refractive index 1.3297 20 °C, relative density of 0.933 g mL-1. The chemical profile showed the following major compounds ocimene<(E)-β-> with 15.87%, caryophyllene E 11.53%, γ-muurolene 20.07%, bicyclogermacrene 16.11% and, rosifoliol with 31.09%. The antioxidant activity showed high efficiency in reducing of the DPPH radical in all concentrations varied between 50 to 0.031 mg mL -1 between 95.25% to 40.09%. The antifungal activity showed 100% of mycelial inhibition in 100 and 50 µL mL-1 concentrations for S. sclerotinia, C. gloeosporioides and A. flavus. In the lowest concentration of 1.56 µL mL-1 inhibition was also observed for S. sclerotiorum and A. flavus and for 3.13 µL mL-1 for C. gloeosporioides with 26.12; 6.08 and 10.07%, respectively. The essential oil of the flowers from C. regium proved to be an efficient natural product for the development of medicines, as an antioxidant agent and, antifungal for agricultural use.
Qualidade de mudas de mamoeiro Formosa (Carica papaya L.) produzidas em substratos com rejeitos de mica na composição e fertilização com urina de vaca
Authors: Santos Naelson Araújo dos , Freire José Lucínio De Oliveira , Silva Jaiane Eva Da , Barreto Neto José Gomes , Dias Cícero Silva , Nascimento Gislaine Dos Santos
Published: November 2020

Although papaya (Carica papaya L.) is one of the most expressive crops of Brazilian fruit, there is no information on the production of seedlings of this species on substrates with muscovite tailings (mica) and the use of cow urine as an organic fertilizer. The objective of this research was to evaluate the influence of substrates with different proportions of mica and with the use of cow urine as organic fertilizer on the quality of Formosa papaya seedlings. The experimental design was completely randomized in a 5 x 2 factorial arrangement, corresponding to the percentages of 0.0%; 25.0%; 50.0%; 75.0% and 100.0% mica in the substrate with and without weekly application of cow’s urine diluted in water (5.0%) and fifteen repetitions. The variables analyzed were stem height / diameter ratio, total leaf area, shoot dry mass, root dry mass, total dry mass, leaf biomass allocation, stem biomass allocation, root biomass allocation and Dickson quality index. Formosa papaya seedlings with better agronomic quality were produced with substrate with 48.3% mica in the composition and weekly application of cow urine diluted in 5.0% water 
Employees of Greatness: Signifying Values in Performance Appraisal Criteria
Authors: Eriksson Ylva Ulfsdotter , Larsson Bengt , Adolfsson Petra
Published: November 2020

The spread of performance-based and variable pay systems has affected expectations on employee contributions and remuneration, which have become increasingly personalized and individualized. Based on a theoretical valuation studies approach, this study of performance-based pay systems in Sweden shows that performance appraisals are (e)valuations of employees’ yearly performance in which they are prized and (ap)praised at the same time. Through a document analysis of performance criteria from four organizations, the study analyzes how values expressed refer to Boltanski and Thévenot’s six orders of worth. The analysis resulted in a theoretical construction of a joint ideal of Employees of Greatness, against which employees are measured and remunerated. The existence of the ideal of employee greatness is explained by the increasing congruence of organizational ideals in private and public sectors, as principles from emotional and cognitive forms of capitalist organization are superimposed on traditional industrial capitalist organizational ideals.
Regularities in ammonoid evolution and detailed zonal scale of the upper anisian, ladinian and carnian of Northeast Asia
Authors:   Trofimuk Institute of Petroleum Geology and Geophysics SB RAS, Konstantinov Alexey G.
Published: November 2020

The main development directions of the ammonoids of the families Beyrichitidae, Tsvetkovitidae, Nathorstitidae and Sirenitidae with high evolutionary rates are considered. These ammonoids are widespread in the Middle and Upper Triassic deposits of Northeast Asia and other boreal regions. The morphological and genetic sequences of the genera and species of beyrichitids, tsvetkovitids, nathorstitids, and sirenitids have been identified. They reflect distinct phases in the evolution of the families and represent the basis of the detailed zonal scale for the Upper Anisian, Ladinian, the uppermost Lower Carnian and Upper Carnian of Northeast Asia.
Palynological characteristic of the border cretaceous and paleogene deposits in the Sourth of Trans-Ural region (bh 9, Troizk)
Authors:   Trofimuk Institute of Petroleum Geology and Geophysics SB RAS, Kuzmina Olga B. , Lebedeva Natalia K. ,   Trofimuk Institute of Petroleum Geology and Geophysics SB RAS; Novosibirsk State University
Published: November 2020

The Upper Cretaceous and Paleogene sediments exposed in Borehole 9 (Troizk, Chelyabinsk Area) in the south of the Trans-Ural Region (Western Siberia) are studied by palynological methods. The BH9 has uncovered the Fadyushinskaya and Gan’kino formations of Upper Cretacious age and the Talitsa, Serov, Irbit, Chegan and Kurtamysh formations of Paleogene age. Nine dinocysts assemblages and nine spores and pollen assemblages were revealed. The Campanian, Maastrichtian, Late Paleocene, Low-Middle Eocene and Early Oligocene age of the sediments were substantiated.
Optimization of Copyright as Fiduciary Guarantee in Increasing Business Productivity
Authors: Argaputri Adinda Annisa , Asikin Zainal , Hayyanul Haq L. M.
Published: November 2020

This study aims to determine how the requirements for transferring economic rights to copyright optimization as a Fiduciary Guarantee in increasing business productivity, how to determine the economic value in optimizing Copyright as Fiduciary Guarantee in increasing business productivity, and what are the roles and responsibilities of a Notary in making a Guarantee Act. Fiduciary on Copyright in increasing business productivity. The theory used is utility / utilitarianism theory, reward theory, legal certainty theory, and legal responsibility theory. The results of the study show that copyright can be an object of Fiduciary Guarantee due to exclusive rights, namely economic rights owned by the copyright owner. The method used is a normative legal research method. Techniques for studying and analyzing legal materials are using documentary studies. The results of the research show that copyright can be used as an object of Fiduciary Security because copyright is a movable object that is not tangible and that can be transferred to only economic rights to be guaranteed. The requirements for the transfer of economic rights follow the procedures stipulated by UUJF. The current method of assessing the economic value of a Copyright is by using quantitative methods. It consists of a market approach, an income approach and a cost approach. The role of the notary in this case in making the fiduciary guarantee deed has been mentioned in Article 5 paragraph (1) of the UUJF and is based on the responsibilities in effect since taking the oath of office as regulated in Article 65 of the UUJN. Notaries do not participate and are responsible for determining the economic value of a copyright. This is the duty and authority of the Appraisal Agency.
Risk Mitigation in Cooperation Through Channeling Financing between Sharia Companies and Sharia Banks
Authors: Setiawati Nur Utari
Published: November 2020

Cooperation through channeling between Sharia (Islamic) company and financial institutions can be done as long as it does not conflict with the principles of sharia. The purpose of this research is to analyze the risk mitigation of financing, especially in the cooperation between Islamic companies and financial institutions regarding the channeling financing. This research is normative study by statutory approach and a conceptual approach. Channeling financing should be done by fulfilling the principles of justice, balance, beneficence and universalism and not contain any gharar, maisir, usury, wrongdoing and haram objects. The contract that frames this collaboration is wakalah bil ujrah. Sharia companies as representatives of financial institutions that distribute sharia financing to customers receives compensation (ujrah) from managing the funds. Channeling financing, does not rule out the risk of mistakes (wanprestasi), therefore, if there is a mistake the one that took the risk is financial institution while Sharia Company does not take the risk. However, it is possible for Sharia Company to take the risks if Sharia Company does not mitigate the risk that should be carried out by the Sharia Company. It is concluded that, it is possible for Sharia Company to take the risks if Sharia Company does not mitigate the risk that should be carried out by Sharia Company in channeling Sharia financing to its customers.
Analysis of Regional People's Representative Council (DPRD) Comparative Study Activities in Efforts to Suppress Corruptive Behaviour
Authors: Harmono Harmono , Manullang Sardjana Orba , Nugraha Krisna , Umar Jaenudin , Rachmawati Irma , Nurwanty Iis Isnaeni
Published: November 2020

One of the duties and authorities of the Regional People's Representative Council (DPRD) is to draw up regional regulations. To carry out this task, DPRD members will usually conduct comparative study activities to other regions. As a consequence, state finances are used to finance these activities. This research took place in the city of Cirebon, West Java. This research focuses on the effectiveness of comparative study activities carried out by the DPRD with the performance achievement target. Also, this research will answer whether comparative study activities have regulations that can limit the corrupt behaviour of DPRD members. This research uses descriptive research method. This study concludes that the implementation of work visits and comparative studies conducted by the Cirebon City DPRD in 2017 and 2018 in the framework of preparing the Cirebon City Regional Regulation is following the regulations. The regulation is based on the Standing Orders of Cirebon City DPRD members. However, the implementation of this comparative study has not been effective in supporting the improvement of the performance of DPRD thus it has the potential to cause acts of corruption.
Legal Analysis of Supporting Methods of Foreign Investors in Nationalization and Property Confiscation
Authors: Maleki Javad Sabih , Karamzadeh Siamak
Published: November 2020

Nationalization of foreign investor assets does not serve the interests of countries because it disrupts the economic security of states and ultimately leads to a reduction in foreign investment. Governments have sought to minimize investor nationalization and property confiscation in order to attract foreign investment. In the event of expropriation of a foreign investor, governments are required to compensate the investor. The position of customary international law on how to pay compensation and methods of assessing damages includes procedures based on national law, treaties and judicial decisions or arbitration. In order to support investors, it is necessary that the right to nationalize property and expropriation of investors should be very limited. Further, in case of nationalization, the damage must be compensated in a desirable and effective manner. The foreign investor must enjoy the same rights as domestic investors and at the same time have the right to transfer their capital and profits abroad. Appropriate measures should also be taken to amend national laws in order to consolidate and guarantee the ownership of foreign investors.
A aplicação da mediação à resolução de conflitos ambientais
Authors: Colombo Silvana Raquel Brendler
Published: November 2020

A morosidade do Poder Judiciário, a dificuldade na produção de prova e os questionamentos técnicos são mais onerosos na área ambiental devido à irreversibilidade da quase totalidade dos danos ambientais. Por isso, é preciso pensar em uma alternativa mais célere, eficiente e participativa do que o processo judicial, como a mediação, que é marcada pela autonomia das partes na construção da solução do conflito, o que resulta em maior comprometimento com as obrigações assumidas. Como a definição de método está diretamente relacionada ao problema de pesquisa, às hipóteses e aos objetivos, optou-se como método de abordagem para desenvolver o tema escolhido, o método dedutivo, pois o primeiro capítulo abordou a mediação e os aspectos gerais do marco legal, assim como o segundo capítulo discorreu sobre a Ação Civil Pública, instrumento processual destinado à tutela ambiental, para apresentar nos dois últimos uma proposta de mediação aplicada aos conflitos ambientais. Trata-se de uma pesquisa qualitativa e, nessa perspectiva, depois da leitura da bibliografia selecionada e a revisão bibliográfica, investiu-se na abordagem empírica do objeto. O instrumento de coleta de dados escolhido foi o questionário, com perguntas abertas, para conhecer a opinião dos Magistrados, Promotores de Justiça, Advogados e Professores sobre a mediação ambiental, e levantamento de dados, cuja amostra é de pequena grandeza, sobre as ACPs ambientais julgadas em 2017 junto às Câmaras Reservadas ao meio ambiente do TJ/SP. Verificou-se que as vantagens da mediação em relação à decisão judicial não são apenas identificadas sob a perspectiva quantitativa, traduzida na celeridade, mas também sob a perspectiva qualitativa, maior comprometimento das partes com a solução acordada, pois são elas que detêm o poder de decisão. Concluiu-se, também, que a indisponibilidade do direito ao meio ambiente não impede a negociação, não no sentido de renúncia ou disposição sobre o direito, e, sim, em relação à melhor forma de protegê-lo ou concretizá-lo, uma vez que a morosidade na área ambiental pode levá-lo ao perecimento.
A cultura dos direitos culturais
Authors: Luther Joerg
Published: November 2020

O ensaio inicia com uma revisão das incertezas que permeiam o conceito de “direitos culturais”, questão que é fortemente ligada à indeterminação do próprio conceito de “cultura”. Realiza-se um estudo comparativo filológico sobre o conceito de cultura no sentido do que é relevante quanto à universalidade dos direitos culturais. O artigo enfoca na análise do conceito de “cultura legal de culturas”, da obra de Peter Häberle, que é necessário para o estudo do papel dos direitos culturais no constitucionalismo contemporâneo. Analisa-se a origem dos direitos culturais, através de uma revisão das legislações, que frequentemente são fragmentadas e podem estar sujeitas a interpretações sistemáticas e evolutivas. Em seguida, prossegue-se com a análise das garantias legais de proteção aos direitos culturais no estado da arte. O ensaio termina com a exposição de alguns dos desafios futuros que definirão o debate sobre a lei e a cultura dos direitos fundamentais culturais.
Prediction of MTTF of Rotary Microcryogenic Gas Machines (Microcryocoolers) based on the Weibull Distribution Law
Authors: Arkharov I.A. , Navasardyan E.S. , Shishova N.E.
Published: November 2020

In this paper, we analyze the methods for predicting the MTTF of microcryocoolers of various manufacturers based on the Weibull law. The values of the shape and scale parameters of the Weibull distribution law for rotary microcryocoolers of various foreign manufacturers and a method for calculating the shape and scale parameters of this law are applied to the data obtained from experimental studies of microcryocooler samples. The limiting values of the shape variable were estimated and the methods for calculating the scale parameter needed to predict the MTTF of the microcryocooler both at the stage of improving existing models and at the stage of designing newly developed samples are presented. It seems that the approach to predicting the MTTF of the microcryocooler described in the work will allow us to determine the parameters of the Weibull distribution function for specific values set by the customer of the MTTF of the created microcryocooler sample, which in turn will allow the selection of machine components (assemblies and details) also for a specific values of MTTF
Simulation of the Scattering Process Effect on High-Temperature Jet Radiation Intensity by the Monte Carlo Method
Authors: Grigorev I.S.
Published: November 2020

The purpose of the paper was to study the scattering effect in the gas jet model on the angular dependence of the radiation intensity. Along with the Monte Carlo method used as the main calculation method, we applied a direct numerical solution of the equation of radiation transfer in a non-scattering medium, known as the discrete directions method, or Ray-Tracing Method. We compared the results obtained using the two methods when calculating a non-scattering medium in order to verify the solution according to the Monte Carlo scheme. Furthermore, we calculated the medium with an increasing value of the local scattering coefficient. Findings of research show the significant effect of scattering processes on the redistribution of radiation energy from the surface of the object. The computational algorithm is implemented on the CUDA C architecture. The use of analytical jet models, e.g. according to Abramovich's theory, and the results of calculations in the computational gas dynamics packages makes it possible to calculate the values of the radiation intensity for a wide class of objects
On Preserving the Historical Memory of the First Half of the 20th Century. Introduction to Considerations about the Past of Education
Authors: Michalski Grzegorz
Published: November 2020

In the context of reflections on the breakthrough moments in the history of Poland in the first half of the 20th century, the content of the volume of the journal “Nauki o Wychowaniu. Studia Interdyscyplinarne” (Nowis. Interdisciplinary Studies) which testifies to the preservation of their historical memory, is discussed.
Działalność Komisji Kół Krajoznawczych Młodzieży Szkolnej w Polsce okresu międzywojennego
Authors: Magiera Elżbieta
Published: November 2020

Artykuł dotyczy działalności Komisji Kół Krajoznawczych Młodzieży Szkolnej w Polsce okresu międzywojennego. Ukazuje okoliczności utworzenia Komisji, jej skład oraz regulamin. Przedstawia obszary działalności Komisji, która nadawała jednolity kierunek pracy kołom krajoznawczym młodzieży. Prezentuje rozwój struktur organizacyjnych ruchu krajoznawczego młodzieży. Komisja Kół Krajoznawczych Młodzieży Szkolnej była organem kierującym, opiekującym się i dbającym o rozwój kół krajoznawczych młodzieży w Polsce w okresie międzywojennym.
Antiplatelet therapy in cardiology
Authors: Popova Lyudmila V. , Aksenova M. B. , Khlevchuk T. V.
Published: November 2020

Platelets are important components of hemostasis and play a key role in the formation of atherothrombosis. Rupture or erosion of atherosclerotic plaque gives rise to a thrombus with the involvement of platelets. Antiplatelet agents are instrumental in preventing the development of atherothrombosis of different localization, including coronary arteries.
Efficacy of combined therapy of non-alcoholic fatty liver disease with succinate-containing drugs
Authors: Stel’makh Viktoriya V. , Nekrasova A. S. , Kozlov V. K. , Kotiv M. Ja. , Karpenko M. N.
Published: November 2020

Aim. To study the safety and tolerability of combined pathogenetic therapy of non-alcoholic fatty liver disease with the use of succinate-containing drugs (remaxol, cytoflavin) and its influence on the functional state of liver and lipid metabolism in patients with non-alcoholic steatohepatitis (NASH) and metabolic syndrome. Materials and methods. The study included 62 patients (52% men and 48% women) at the mean age of 50,18±2,38 yr. The treatment included electrolyte solutions, vitamins, enzymes, herbal preparations (milk thistle), essential phospholipids, antihypertensive drugs, and a course of infusion therapy with a metabolic corrector showing hepatoprotective activity (remaxol, 400 ml i/v for 11 days). Patients with hyperenzymemia were additionally given 1-3 courses of therapy with oral succinate-containing cytoprotector cytoflavin (1 tablets t.p.d for at least 10 days per month during a total of 6 months). If appropriate (signs of cytolysis and cholestasis) remaxol therapy was repeated once in 6 months with subsequent transition to oral cytoflavin till complete regression of hyperenzymemia. Results. 74% of the patients treated with remaxol and cytoflavin experienced normalization of enzymemia (ALT and AST). Triglyceride levels decreased to the normal values in 39% of the cases. Conclusion. Inclusion of succinate-containing drugs (remaxol, cytoflavin) in combined treatment of NASH and metabolic syndrome promotes normalization of hepatic function and has marked lipid-regulating effect.
Levofloxacin: the role and significance in the treatment of lower respiratory tract infections
Authors: Sinopal’nikov Aleksandr I.
Published: November 2020

The advent of the first «respiratory» fluoroquinolone in the late 1990s gave rise to a dramatic growth in popularity ofantibiotics of this class. Levofloxacin like other fluoroquinolones is highly active with respect to Gram-positive, Gram-negative, and atypical pathogens including penicillin-resistant strains of Streptococcus pneumoniae. It is recommended for the treatment of community-acquired pneumonia, nosocomial pneumonia, and exacerbations of chronic obstructive pulmonary disease. Levofloxacin is safe and characterized by high bioavailability and high concentration at the site of inflammation. Therapy with its high doses (750 and 1000 mg/day) during 5 days improves the outcome of the treatment due to improved compliance and minimal risk of development of drug resistance. nosocomial pneumonia, exacerbations of chronic obstructive pulmonary disease.
Peripartum cardiomyopathy
Authors: Golitsyna N. A. , Il’ina Tat’yana E. , Koroleva L. Yu. , Amineva N. V. , Borovkov N. N.
Published: November 2020

The article describes a clinical case of peripartum cardiomyopathy (PPCM) in a 25 year old patient. The disease developed after emergency cesarean section necessitated by severe preeclampsia on week 37 of the first pregnancy. Differential diagnosis between acute myocarditis, idiopathic dilated cardiomyopathy was performed. Taking into account the relationship between rapidly evolving symptoms of left ventricular heart failure and first pregnancy in the healthy woman, the lack of convincing evidence for myocarditis, dilatation of cardiac cavities and 25% reduction of ejection fraction, PPCM was diagnosed. The treatment resulted in a pronounced clinical effect.
The quality of life in the residents of the Middle Ob’ region presenting with arterial hypertension
Authors: Sirusina Ad. V. , Chibisov S. M. , Ragozin Oleg N.
Published: November 2020

Hypertension alters the qualitative parameters defining and limiting the quality of life in the inhabitants of Northern regions exposed to homeostatic stress. Gender differences are manifest as a significant deterioration of the physical component of the quality of life in women with arterial hypertension and a limitation of role functioning in men.
Clinical and pathogenetic peculiarities of development of endothelial dysfunction and arterial rigidity in patients with chronic obstructive pulmonary disease
Authors: Mamaeva Marina G. , Demko I. V. , Salmina A. B. , Sobko E. A. , Malinovskaya N. A. , Kraposhina A. Yu. , Gordeeva N. V. , Solov’eva I. A.
Published: November 2020

The purpose of the study was to examine the relationship between functional parameters, arterial rigidity, lipid profile, markers of systemic inflammation and endothelial dysfunction in patients with COPD and COPD + coronary heart disease. We examined 110 subjects divided into 3 groups. Ggroup 1 included 40 patients with severe and very severe COPD, group 2 consisted of 40 patients with severe and very severe COPD + coronary artery disease, the control group was comprised of 30 healthy volunteers. We studied parameters of respiratory function, the level of blood oxygenation, the main characteristics of arterial rigidity, plasma lipid, TNF-a, CRP, fibrinogen, sPECAM-1 levels and the expression of CD38/ADP-ribosylcyclase in peripheral blood lymphocytes. The study revealed increased rigidity of the central arteries in the patients of groups 1 and 2 regardless of the duration of observation and the presence of coronary artery disease, as evidenced by the increase of the pulse wave velocity in the aorta. Patients of both groups had elevated levels of TNF-a, CRP and fibrinogen indicating systemic inflammatory response. Taken together, the enhanced expression of CD38 in peripheral blood lymphocytes, elevated concentration of soluble CD31 (sPECAM-1) in both groups related to bronchial obstruction and neutrophil elastase activity as well as increased rigidity of the vascular bed gives evidence that the CD38 and sCD31 relationship plays a role in the formation of endothelial dysfunction, and dysregulation of vascular tone in COPD patients. Disorders of lipid metabolism combined with increased rigidity of the vascular wall, elevated levels of markers of systemic inflammation and endothelial dysfunction, suggest that patients with COPD are at risk of cardiovascular events.
Osgood-Schlatter disease
Authors: Shamov Ibragim A.
Published: November 2020

Osgood-Schlatter disease is a specific disorder related to osteochondropathies that affects young subjects and is localized in the tuberositas tibiae. The disease frequently develops after injuries including loading ones. It is apparent as gradual swelling of the knee joint(s) that becomes painful. Pain increases during walking, lower limb flexion an extension or stair climbing but may die down at rest. Diagnostics is based on the clinical picture. Radiodiagnostic methods may be helpful but their efficacy is inferior to that of clinical examination. Anti-inflammatory and chondroprotective therapy, immobilization of the affected joint, controlled exercises, and balneotherapy are indicated.
Modern prokinetics and their role in the treatment of gastroenterological pathology
Authors: Sheptulin Arkady A. , Belousova I. B.
Published: November 2020

The importance ofprokinetics (drugs stimulating motor function of the gastrointestinal tract} arises from the high prevalence of gastroenterological pathology associated with primary or secondary disturbances of this function in esophagus, stomach, and intestines. The main groups of prokinetics are beta-blockers of dopamine receptors, inhibitors of acetylcholine esterase (or their combination with dopamine receptor blockers), 5-HT4-receptor agonists. They find wide application for the treatment of gastroesophgeal reflux disease, functional dyspepsia and constipation, obstipational form of irritable bowel syndrome, and other conditions accompanied by motor function disorders of the gastrointestinal tract.
Predictors of resistant arterial hypertension
Authors: Lazutkina Anna Yu. , Gorbunov V. V.
Published: November 2020

The paper reports results of 6 year prospective observation of 7959 members of locomotive crews engaged at the Transbaikal Railways. The study aimed to estimate the probability and time of development of resistant arterial hypertension under effect of predictors of this disease. The data obtained are of value for diagnostic, prophylactic, and therapeutic practice.
Remote preconditioning phenomenon. prospects for use in pathology of lung and gastrointestinal tract
Authors: Maslov Leonid N. , Tsibulnikov S. Yu. , Tsepokina A. V. , Khutornaya M. V. , Kutikhin A. G. , Tsibulnikova M. R. , Basalay M. V. , Mrochek A. G.
Published: November 2020

The literature data on the effectiveness of remote ischemic preconditioning (RIP) in the prevention of lung injury are contradictory. Authors of some works argue that RIP prevents lung damage during surgical interventions, the authors of other publications claim that the RIP does not protect lung against pathological processes. It is obvious that there is an urgent need for multicenter, randomized trials aimed at studying RIP protective effects against pathological processes in lung. Also required is clinical evaluation of the effectiveness of RIP in the thromboembolism of pulmonary arteries, the transplantation of the lungs and intestinal infarction. Remote preconditioning prevents the intestine injury associated with abdominal aortic aneurysm repair. Experimental data indicate that RIP has the hepatoprotective effect during ischemia and reperfusion injury of liver, septic or haemorrhagic shock. The question of whether the DIP has a protective effect during ischemia-reperfusion of the pancreas remains open.
Disorders of carbohydrate metabolism in chronic obstructive pulmonary disease
Authors: Kobylyansky Vyacheslav I.
Published: November 2020

The literature data and our own experience suggest that chronic obstructive pulmonary disease can be an important risk factor of type 2 diabetes mellitus. The relationship between these two condition is virtually unexplored and pathogenteic mechanisms behind it remain unclear. There are reasons to attribute an important role to insulin resistance as one of the leading mechanisms. It is in the focus of the present work.
The clinical significance of insulin resistance, impaired carbohydrate and lipid metabolism in the development of microcirculation pathology in patients with chronic heart failure and type 2 diabetes mellitus
Authors: Statsenko Mihail E. , Turkina S. V. , Shilina N. N. , Kosivtsova M. A.
Published: November 2020

Patients with chronic heart failure and diabetes mellitus type 2 experience continuous progression of organ damage as a result of hemodynamic and metabolic disorders. An important role in pathogenesis of organ damage belongs to pathological types of microcirculation, endothelial dysfunction and insulin resistance. But the role of insulin resistance and its contribution to the formation of endothelial dysfunction and peculiarities of microcirculation in patients with chronic heart failure and type 2 diabetes mellitus is unknown. This study shows significant association between insulin resistance, disorders of carbohydrate and lipid metabolism, development of microcirculatory disturbances and endothelial dysfunction.
Differential diagnostics of febrile conditions in an emergency care clinic
Authors: Budnevsky A. V. , Esaulenko I. E. , Grechkin V. I. , Romashov Boris B.
Published: November 2020

We undertook the analysis of 157 cases of fever at the stages of polyclinic - admission department - hospital treatment for the purpose of elucidating the structure of febrile syndrome. Pneumonia developed in 45 patients, infectious endocarditis in 34, chronic alcoholic hepatitis in 21, rheumatoid arthritis (pseudoseptic variant) in 2, systemic lupus erythematosus in 1, polymyositis in 2, acute pyelonephritis (exacerbation of chronic pyelonephritis) in 15, tumours of different localization in 37 patients. We evaluated the informative value of some acute-phase blood characteristics obtained, results of X-ray and ultrasonic studies for early diagnostics of pneumonia and infectious endocarditis.
Biliary reflux-gastritis: etiology, pathogenesis and modern principles of treatment
Authors: Tel’nykh Yuri V. , Abgadzhava E. Z. , Kon’kov M. Yu.
Published: November 2020

Objective. To study etiopathogenetic aspects of biliary reflux-gastritis (RG) and develop modern principles of its therapy depending on acidity of stomach contents, atrophy ofgastric mucosa, and Helicobacter pylori infection. Different pathogenetic mechanisms of RG are discussed with special reference to bile flow into the antrum as a result of duodenogastric reflux. It is shown that the use of de-nol and probiotic ProBiotic Complex for the treatment of biliary reflux-gastritis increases effectiveness of H. pylori eradicationby 18.2% and prevents the development of bowel dysbiosis.
Principles of primary prophylaxis of bleeding from oesophagealvaricies in patients with liver cirrhosis
Authors: Garbuzenko Dmitry V.
Published: November 2020

The principles of primary prevention of bleeding from esophageal varices in patients with liver cirrhosis are discussed with reference to the stage ofportal hypertension. The information was collectedfrom the PubMed database, Google Scholar retrieval system, Cochrane reviews, and lists of references from relevant publications for 1980-2015 using the key words «bleeding from esophageal varices», «prophylaxis», «portal hypertension». Inclusion criteria were confined to primary prophylaxis of bleeding from esophageal varices in patients with liver cirrhosis. The analysis showed that the drugs of choice for primary prophylaxis of bleeding from esophageal varices in patients with liver cirrhosis are non-selective beta-adrenoblockers, but their application is indicated only in case of clinicallyl significant portal hypertension in patients with large and mediumsize esophageal varices. When the use of these drugs is contraindicated, endoscopic ligation of esophageal varices can be recommended.
Atheromatosis of arterial intima
Authors: Titov Vladimir N. , Rozhkova T. A. , Amelyushkina V. A.
Published: November 2020

Phylogenetically late arterial intima of the elastic type contains no proteins for the transfer of ligandless oxidized low density lipoproteins (LDLP) for sedentary macrophages adsorbed on the matrix. Phylogenetically early cells realize the extracellular digestive reaction by releasing proteolytic enzymes (metalloproteinases) into intimal matrix that hydrolize matrix proteoglycans, adsorbed ligandless LDLP, detritus, and complete lysosomal hydrolysis of the most hydrophobic polyenic cholesterol esters (poly-ECS). Smooth muscle cells migrate from the middle muscular layer of the arterial wall, change their contractile phenotype to secretory one, and synthesize in situ de novomatrix proteoglycans. The arterial wall has three layers (monolayer endothelium, intimal media (smooth muscle cells), and adventitia) only in elastic type arteries. It is desirable to elucidate functional differences between phylogenetically early sedentarymacrophages and monocytes-macrophages of later origin and understand whether theydepends on specific features of activity of scavenger eceptors, CD36 translocases, expression of acid hydrolases synthesis for poly-ECS or realization of the extracellular digestion reaction. We believe that formation of atheromatous masses takes place in the matrix of arterial intima rather than in lysosomes taking into account limited possibilities for monocytes-macrophages to realize endocytosis of ligandless LDLP from the matrix. Given that atheromatosis is a syndrome of deficit of essential polyenic fatty acids (PFA) in the cells, intimal atheromatosisshould be regarded only as partial utilization of excess PFA in the matrix of elastic type arteries. At later stages of phylogenesis, intima was formed from media smooth muscle cells.
A case of mucoviscidosis in practical work of a pulmonologist
Authors: Demko I. V. , Gordeeva Natal’ya V. , Mamaeva M. G. , Kraposhina A. Yu. , Zeleny S. V. , Guseva I. S. , Solov’eva I. A. , Sobko E. A.
Published: November 2020

A case of late manifestation ofmucoviscidosis is reported. In the past, this pathology was dealt with by pediatricians, but to-day the management of this problem involves a number of different specialists. The progress in clinical practice makes it possible to significantly prolong the life span of patients with this condition. The present case shows that its clinical manifestations may appear at any age.
Regression of atherosclecrotic lesions: medicinal and alimentary factors
Authors: Magaeva S. V. , Kubatiev A. A. , Shirokov E. A. , Simonenko V. B.
Published: November 2020

The article reports results of clinical studies aimed to elucidate the influence of medicines on the size and density of atherosclerotic plaques in the walls of coronary and cerebral arteries. The phenomenon of regression of atherosclerotic lesions in the survivors of Leningrad siege during a long period of starvation is analyzed. The influence of inhibitors of angiotensinconverting enzyme on apoptosis of smooth muscle and foam cells of atherosclerotic plaques in the sanological mechanisms of atherosclerosis is discussed. The concept of natural regression of atherosclerosis is formulated and the necessity of development of the methods for is pharmacological activation are formulated.