bluuebunny/crossref_metadata_2025 huggingface dataset:
Deep venous thrombosis and pulmonary embolism after anterior cruciate ligament reconstruction
Authors: Kraus Schmitz J. , Lindgren V. , Janarv P-M. , Forssblad M. , Stålman A.
Published: January 2019

Aims

The aim of this study was to investigate the incidence, risk factors, and outcome of venous thromboembolism (VTE) following anterior cruciate ligament (ACL) reconstruction in a nationwide cohort.

Patients and Methods

All ACL reconstructions, primary and revision, that were recorded in the Swedish Knee Ligament Register (SKLR) between 2006 and 2013 were linked with data from the Swedish National Board of Health and Welfare. The incidence of VTE was determined by entries between the day of surgery until 90 days postoperatively based on diagnosis codes and the prescription of anticoagulants. Risk factors, outcome, and the use of thromboprophylaxis were analyzed. Descriptive statistics with multivariate analysis were used to describe the findings.

Results

The cohort consisted of 26 014 primary and revision ACL reconstructions. There were 89 deep venous thromboses (DVTs) and 12 pulmonary emboli (PEs) with a total of 95 VTEs (0.4 %). Six patients with a PE had a simultaneous DVT. The only independent risk factor for VTE was age greater than or equal to 40 years (odds ratio 2.31, 95% confidence interval 1.45 to 3.70; p < 0.001). Thromboprophylaxis was prescribed to 9461 patients (36%) and was equally distributed between those with and those without a VTE (37.9% vs 36.4%). All patient-reported outcome measures (PROMs) one and two years postoperatively were significantly lower in those with VTE.

Conclusion

The incidence of VTE following ACL reconstruction is 0.4%, and the only significant risk factor is age. Patients with VTE had worse postoperative clinical outcome than patients without VTE. We recommend against the routine use of thromboprophylaxis, but it should be considered in older patients.
Practice variation in total hip arthroplasty versus hemiarthroplasty for treatment of fractured neck of femur in Australia
Authors: Harris I. A. , Cuthbert A. , de Steiger R. , Lewis P. , Graves S. E.
Published: January 2019

Aims

Displaced femoral neck fractures (FNF) may be treated with partial (hemiarthroplasty, HA) or total hip arthroplasty (THA), with recent recommendations advising that THA be used in community-ambulant patients. This study aims to determine the association between the proportion of FNF treated with THA and year of surgery, day of the week, surgeon practice, and private versus public hospitals, adjusting for known confounders.

Patients and Methods

Data from 67 620 patients in the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) from 1999 to 2016 inclusive were used to generate unadjusted and adjusted analyses of the associations between patient, time, surgeon and institution factors, and the proportion of FNF treated with THA.

Results

Overall, THA was used in 23.7% of patients. THA was more frequently used over time, in younger patients, in healthier patients, in cases performed on weekdays (adjusted odds ratio (OR) 1.27; 95% confidence interval (CI) 1.14 to 1.41), in private hospitals (adjusted OR 4.34; 95% CI 3.94 to 4.79) and by surgeons whose hip arthroplasty practice has a relatively higher proportion of elective patients (adjusted OR 1.65; 95% CI 1.49 to 1.83).

Conclusion

Practice variation exists in the proportion of FNF patients treated with THA due to variables other than patient factors. This may reflect variation in resources available and surgeon preference, and uncertainty regarding the relative indication.
The aetiology of posterior glenohumeral dislocations and occurrence of associated injuries
Authors: Kelly M. J. , Holton A. E. , Cassar-Gheiti A. J. , Hanna S. A. , Quinlan J. F. , Molony D. C.
Published: January 2019

Aims

The glenohumeral joint is the most frequently dislocated articulation, but possibly due to the lower prevalence of posterior shoulder dislocations, approximately 50% to 79% of posterior glenohumeral dislocations are missed at initial presentation. The aim of this study was to systematically evaluate the most recent evidence involving the aetiology of posterior glenohumeral dislocations, as well as the diagnosis and treatment.

Materials and Methods

A systematic search was conducted using PubMed (MEDLINE), Web of Science, Embase, and Cochrane (January 1997 to September 2017), with references from articles also evaluated. Studies reporting patients who experienced an acute posterior glenohumeral joint subluxation and/or dislocation, as well as the aetiology of posterior glenohumeral dislocations, were included.

Results

A total of 54 studies met the inclusion criteria. In total, 182 patients were included in this analysis; study sizes ranged from one to 66 patients, with a mean age of 44.2 years (sd 13.7). There was a higher proportion of male patients. In all, 216 shoulders were included with 148 unilateral injuries and 34 bilateral. Seizures were implicated in 38% of patients (n = 69), with falls, road traffic accidents, electric shock, and iatrogenic reasons also described. Time to diagnosis varied across studies from immediate up to a delay of 25 years. Multiple associated injuries are described.

Conclusion

This review provides an up-to-date insight into the aetiology of posterior shoulder dislocations. Our results showed that seizures were most commonly implicated. Overall, reduction was achieved via open means in the majority of shoulders. We also found that delayed diagnosis is common.
Para mim ou para eu fazer? Um retrato da Região Sudeste do Brasil a partir dos dados do Projeto ALiB
Authors: Ferreira da Silva Santos Graziele , Moura Torres Paim Marcela
Published: January 2019

Este estudo tem por foco principal a descrição da realidade linguística do português brasileiro, com base em corpus elaborado sobre a utilização do pronome oblíquo tônico mim como variante para o pronome pessoal reto eu, através dos dados das quatro capitais dos estados da Região Sudeste do Brasil (Belo Horizonte – MG, São Paulo – SP, Vitória – ES e Rio de Janeiro – RJ), pertencentes ao Projeto Atlas Linguístico do Brasil – Projeto ALiB. Para tanto, o trabalho descreve e analisa o comportamento dos pronomes eu e mim, em posição de sujeito de infinitivo precedido da preposição para, levando em conta as variáveis sociais: sexo, faixa etária e escolaridade, aplicando, assim, princípios teóricos e metodológicos da Sociolinguística Variacionista. Os resultados obtidos revelaram o caráter heterogêneo da Língua Portuguesa falada no Brasil, desmistificando, desse modo, a ideia de homogeneidade linguística.
O USO VARIÁVEL DOS CLÍTICOS ACUSATIVOS PARA REFERENCIAR O INTERLOCUTOR
Authors: Gama Deyse Edberg Ribeiro Silva
Published: January 2019

Este trabalho traz uma análise sobre o uso variável das formas clíticas te e lhe como estratégias de referência à segunda pessoa do singular, no Português do Brasil (PB) e, para tal, respaldou-se em dados de fala oral, coletados do município baiano de Feira de Santana, no interior do estado. Dentre os resultados, destacam-se os grupos de fatores faixa etária e escolaridade, sendo os falantes a partir de 65 anos (faixa III) os que mais fazem uso do clítico lhe para referenciarem o interlocutor. A escolaridade dos informantes confirma a hipótese de que os falantes com menor escolaridade fazem maior uso do clítico em sua forma não canônica, referenciando a segunda pessoa. Dessa maneira, este estudo agrega dados sobre a investigação de lhe como objeto direto de segunda pessoa em Feira de Santana, assim como em outras variedades do PB.
Evaluation of the heavy metals (mercury, lead, and cadmium) contamination of sardine (Sardina pilchardus) and swordfish (Xiphias gladius) fished in three Algerian coasts
Authors: Mehouel Fetta , Bouayad Leila , Hammoudi Abdel Hamid , Ayadi Ouarda , Regad Fifi
Published: January 2019

Aim: This study aimed to evaluate mercury (Hg), cadmium (Cd), and lead (Pb) levels in 70 samples of sardine (Sardina pilchardus) and 30 samples of swordfish (Xiphias gladius) fished in the Algerian coasts. Materials and Methods: After the mineralization of the fish samples through the pressure digestion, the analyses were carried out by inductively coupled plasma atomic emission spectroscopy. Results: Mean concentrations of Hg, Cd, and Pb in sardine were 0.62, 0.55, and 2.13 mg/kg wet weight, respectively, while in swordfish, the concentrations were 0.56, 0.57, and 3.9 mg/kg wet weight, respectively. These results exceeded the Algerian and European legislation threshold values, whereas Hg's concentration in swordfish remained close to and did not exceed the recommended thresholds (0.56 mg/kg wet weight). Conclusion: This fish may represent a hazard for consumers in Algeria. Systematic and periodic controls of heavy metals in fish are recommended, and risk assessment is needed to protect the consumer.
BIOLEACHING UNTUK MENINGKATKAN PRODUKTIVITAS LAHAN SULFAT MASAM AKTUAL UNTUK TANAMAN PADI
Authors: Maftu’ah Eni , Susilawati Ani
Published: January 2019

Technology of microbial utilization to accelerate the oxidation of pyrite followed by leaching (bioleaching) has the potential to resolve problems in land management of actual acid sulphate soil. The research aims to obtain a bioleaching technology package that can improve the productivity of the actual acid sulfate soil. The experiment was conducted on tidal swamp land that has soil type of actual acid sulfate at Wana Raya sub-district, district Batola, South Kalimantan, in July - November, 2014. The study was designed by using strip plot with three replications. The treatment consisted of two factors, namely application of an oxidizing microbial pyrite and leaching amount (intensity). The main plot consisted of (P0) without leacing (naturally), (P1) six times leaching , (P2) eight times leaching, and (P3) 12 times leaching. Subplot consisted of (M0) without oxidizing microbial pyrite, (M1) with oxidizing microbial plant used in this study is Inpara 3 of rice variety. Observations were made on soil pH, oxidizing bacteria pyrite, growth of rice plants (plant height and number of tillers) and rice yield. The results showed that the main problem of actual acid sulfate land studied is a high soil acidity (pH of 3.44). Influ-ence of leaching was greater than microbial application on crop yields. Application of the pyrite oxidizing bacterial and leaching eight times gave the best influence on the growth and yield of rice plants.
GAMBARAN KECEMASAN ATLET MAHASISWA: STUDI PADA UNIT KEGIATAN MAHASISWA (UKM) OLAH RAGA UNIVERSITAS ISLAM MAULANA MALIK IBRAHIM MALANG
Authors: Pristiwa Lalu Gigir Gilas , Nuqul Fathul Lubabin
Published: January 2019

Abstract. Fighting anxiety often occurs in male and female athletes, as well as individual group sports and sports. The anxiety is a feeling of worry, anxiety, and uneasiness by considering the game as something dangerous. There are many factors that can cause an athlete to experience anxiety during a match that is dysfunctional thoughts and stress, academic problems, anxiety injuries, and poor team relationships. Other factors also exist from such individuals and the environment, such as negative thoughts on the outcome of the game, the pressure of the coach or supporters. Therefore, the fighting anxiety is very important to be known by every athlete or team that will compete, in order to be able to improve its best performance in the face of the game. This study used a quantitative approach measured using the scale of The Sport Interference Checklist (SIC) to measure athlete's anxiety. The subjects of the study were 110 people consisting of athletes of students in the Sports  student Unit State Islamic University Maulana Malik Ibrahim Malang. With male gender of 64 people and 46 women, as well as individual sports from two sports that is badminton and table tennis totaling 31 people and sports groups from four sports that is soccer, volleyball, basketball, and sepak takraw amounted to 79 person. The analysis is descriptive analysis. The results showed that there was no difference between sex of male athlete with percentage 63,00% and woman equal to 66,89%, because anxiety at athlete evaluated from gender have no significance, and difference between type of individual sport with percentage 67, 12% and sports groups of 63.64%, if reviewed the anxiety of the athlete's sports type does not have significant. This means that athletes in the Sport students Unit equally have anxiety problems when playing.
Cuba, Che Guevara, and the Problem of "Socialism in One Country"
Authors: Augustin Ron
Published: January 2019

The presidential elections in Cuba in March 2018 has raised again the question of the country’s survival. How can Cuba hold up and develop against the economic, cultural, and military encirclement of U.S. imperialism in particular and the capitalist system in general? An answer can be sought in the history of Cuba’s socialist transition, the unique role played by Che Guevara, and the emergence of ideas regarding the possibility (and impossibility) of achieving socialism in one country alone.
Capitalism and Mental Health
Authors: Matthews David
Published: January 2019

The psychoanalytical framework developed by Marxist Erich Fromm strongly challenges the dominant biological and individualistic explanations of the mental-health crisis that is now sweeping the globe. Fromm emphasized that all humans have certain needs that must be fulfilled in order to ensure optimal mental health. It follows that capitalism is crucial to determining the experience and prevalence of mental well-being, as its operations are incompatible with true human need.
Formation of the Mechanism of Corporate Social and Environmental Responsibility of the Trading Company
Authors: CHORTOK Yulija , YEVDOKYMOVA Alona , SERPENINOVA Yuliya
Published: January 2019

It was determined that the impact of corporate social and environmental responsibility (CSER) on the formation of the company’s distribution policy has more integrated mechanism than previously assumed. The article emphasizes the fact that all intermediaries (major, regional, local distributors) must comply with the principles and provisions of СSER of manufacturer as the brand owner at the stage of providing consumer with the products. CSER mechanism of the trading company is suggested to form a sales management strategy for a trading company, that is developed on the basis of CSER of manufacturer and aimed at improving economic results and improving social, environmental and economic state of the territory. The conceptual foundations of the mechanism of cooperation with the local distributor are proposed and the expediency of its attraction, which is based on the analysis of the BCG matrix, is justified using Sumy affiliated branch of LLC Bayadera Logistic as case study.
International Regulation of Environmental Auditing in the Countries of the European Union
Authors: ZHATKANBAYEVA Aizhan E. , TUYAKBAYEVA Nazgul S. , JANGABULOVA Araylym K. , ALIBEKOV Sailaubek T. , KASATKINA Elena V. , MASLIHOVA Elena A.
Published: January 2019

In the context of the global environmental crisis that is currently one of the most real threats to the existence of mankind the protection and improvement of the quality of the environment is recognized as a world-wide task, acquires exceptional importance, and is a necessary condition for preserving the health, well-being and economic prosperity of the present and future generations of people. The authors note that the recognition of the global nature of environmental problems by the scientific and political elites of the world's leading countries and their associations, among which one of the most influential and powerful is the European Union, calls for intensified cooperation at the international level to adjust existing and develop new approaches to environmental protection, creation of effective mechanisms for the implementation of the newest environmental policy. These factors contribute to the formation of a new philosophy and practice of European economic interaction based on the need for assistance from stronger participants in the world economy to be weak in solving the interrelated tasks of the economy and ecology.
Green Constitution: Strengthening Environment Principle in the Act of 1945
Authors: NAIBORHU Netty S.R.
Published: January 2019

Environmental issues should not be placed on one side, namely the government (legislative, executive and judicative), but all components of the existing layer in a country must be able to interpret the green constitution in the hearts of each. Green constitution as the idea of constitutionalizing the norm of environmental law into the constitution by raising the draft of environmental protection norms to the constitution level. Approach method used in this research using a normative juridical approach with the focus related to the green constitution as reinforcement of environmental principles in the Constitution with data obtained and analyzed by using a qualitative normative method. This constitutionalization can be grouped into three types. First, formal constitutionalization. This group has a style in which the constitutionalization of environmental policy is carried out by putting it in a formal form on the environment and ideas of sustainable development; Secondly, substantial Constitutionalization. This model is interpreted as a practice of constitutionalization that is not only limited to formal but substantially. As for a reason, that environmental policy becomes the spirit (spirit) of the constitution in a country, Third, structural constitutionalization. This model is an extreme ending which changes the environmental paradigm of the object into the subject of human rights so that the environment can be viewed as a separate legal subject structure beside the human subject.
The Formation of the Efficient System of Ecological Enterprise
Authors: YASNOLOB Ilona , GORB Oleg , OPARA Nadiia , SHEJKO Serhii , PYSARENKO Svitlana , MYKHAІLOVA Olena , MOKIIENKO Tetyana
Published: January 2019

The necessity of using ecologically oriented approach in the process of production by developing and introducing the system of ecological management was investigated in the article. The general principles of its formation with the directions of actions and results were determined. 14 principles of efficient management of V.Ye. Deming for raising the efficiency of ecological management system were adapted with the aim of its constant improving, ensuring long-term developing of enterprise, and raising its competitiveness. The conducting of SWOT-analysis in the system of ecological management was suggested for determining the strategies of enterprise activities, further improving and raising the efficiency of this system. The model of forming the efficient system of enterprise ecological management was suggested. The improvement and efficiency of this system presupposes using general principles and those of efficiency, external environmental information, and SWOT-analysis. The international experience of inefficient ecological management, proving the expediency of using the system of enterprise ecological management, was shown.
Willingness to Pay for Existence Value of Mangrove Ecosystem in Youtefa Bay, Jayapura, Indonesia
Authors: HAMUNA Baigo , RUMAHORBO Basa T. , KEILUHU Henderina J. , ALIANTO ALIANTO
Published: January 2019

Mangrove area in Youtefa Bay is very important for the local people’s lives in around the Youtefa Bay. Willingness to pay (WTP) of the local’s people toward the mangrove ecosystem is their appreciation for existence value of mangrove ecosystem. This research explored how much the WTP was given by the local people toward the mangrove ecosystem existence in Youtefa Bay. The data collection was conducted in March to April 2018 located in three villages around the Youtefa Bay, namely Tobati (46 respondents), Enggros (82 respondents) and Nafri Villages (100 respondents). WTP value collection technique used contingent valuation method (CVM). Result of this research showed that there were 92.98% (212 respondents) who were willing to contribute or pay and 7.02 % (16 respondents) were not. The obtained WTP value of respondents ranged between IDR 0 to IDR 200,000.00 with mean WTP of respondent was IDR 56,052.63/year meanwhile aggregate WTP was IDR 28,811,052.63/year. Variables which had significant influence toward WTP value were earnings and participation and seminaries/trainings/workshops regarding to mangrove ecosystem. Meanwhile gender, age, education level and occupation variables didn’t make any significant influence toward the given WTP value amount.
Effects of Ganoderma lucidum Extract on Diabetic Rats
Authors: Ratnaningtyas Nuniek Ina , Hernayanti Hernayanti , Andarwanti Suci , Ekowati Nuraeni , Purwanti Endang Sri , Sukmawati Dalia
Published: January 2019

Diabetes mellitus (DM) is a metabolic syndrome which occurs when insulin is insufficiently produced or insulin cannot well serve its function. Diabetes is marked with increase in blood glucose level followed by increase in glycosylated hemoglobin level and decrease in insulin level. This research aims to examining the effect of Ganoderma lucidum extract on the blood glucose, insulin and glycosylated hemoglobin (HbA1c) level of diabetic white rat and determining the most effective dose of extract to be a diabetic agent. This research was experimentally conducted by employing Completely Randomized Design (CRD) with 6 treatments and 4 repetitions. The treatment groups consisted of healthy rats group (K1), rats with diabetes as negative control (K2), diabetic rats with the administration of metformin 45 mg/kg BW as the comparison (K3) and diabetic rats with the administration of G. lucidum extract with dose of 250, 500 and 1000 mg /kg BW (K4, K5 and K6 respectively). Blood glucose level examination was conducted after the alloxan induction with single dose of 125 mg/kg BW by intraperitoneal injection. The results show that mushroom G. lucidum extract administration with dose of 1000 mg/kg BW (K6) is the best dose to be an anti-diabetic agent. The benefit of the research is developing anti-diabetic agent from herbal resources.
Purification and Partial Characterization of α-Amylase Produced by a Thermo-Halophilic Bacterium Isolate PLS 75
Authors: Iqbalsyah Teuku M. , Fajarna Farah , Febriani Febriani
Published: January 2019

Bio-based industries require stable enzymes in a broad range of environmental conditions. Extremophiles have attracted more interests as the source of such enzymes, one of which is α-amylase. This study aimed to purify and characterize α-amylase produced by a thermo-halophilic bacterium PLS 75 isolated from underwater fumaroles. Ammonium sulfate precipitation results showed that the highest specific α-amylase activity (21.7 U/mg) obtained at 40-60% saturation level, with a purity of 7.7-fold of the crude extract with 16.2% yield. Further purification using DEAE Sepharose column chromatography increased the enzyme purity 11.1-fold of the crude extract with 7.1% yield. Specific activity after column chromatography purification was 31.3 U/mg. The pure enzyme had a low molecular weight of 14 kDa. The enzyme showed the highest activity at 80 °C and pH 5. The activity increased to 126% when in methanol, while decreased when in ethyl acetate and chloroform. The characteristics of α-amylase with low molecular weight, which was active in acidic condition, stable in polar and non-polar solvents, may be used for for specific industrial needs.
The Correlation Between Heavy Metal and Nutrient Content in Plecostomus (Pterygoplichthys pardalis) from Ciliwung River in Jakarta
Authors: Elfidasari Dewi , Ismi Laksmi Nurul , Shabira Afina Putri , Sugoro Irawan
Published: January 2019

Most of the rivers’ quality in Indonesia is in highly-polluted status including Ciliwung River in Jakarta. The pollution can affect river ecosystem especially the rivers biota such as plecostomus species that is mostly found in Ciliwung River. The information about correlation between heavy metal and nutrition content in Plecostomus flesh still limited, so the result from this research can give the new information about that. The aims of this research is identifying the effect of the heavy metals towards the contents of protein and fat of plecostomus flesh from Ciliwung River. The analyses methods use X-Ray Fluoresence (XRF) Spectrometer, the analysis of protein using kjeldahl method, and fat analysis using extraction method. The result of this research showed that small-sized plecostomus contained the highest fat and protein compared to medium-sized and big-sized plecostomus. The assumption was the contents of heavy metal which can impede protein and fat absorption. Meanwhile, the content of carbohydrate in small-sized plecostomus was the lowest. The identified type of heavy metal using XRF method was Pb, Hg and Cd with the concentration was higher than the maximum standard (SNI) so that the flesh of plecostomus from Ciliwung River in Jakarta is categorized unsuitable to consumption
Plantlets Regeneration from Crown Bud Slicing of Pineapple (Ananas comosus)
Authors: Zulkarnain Zulkarnain , Neliyati Neliyati , Eliyanti Eliyanti
Published: January 2019

Pineapple propagation by lateral shoots, suckers or crowns is often confronted with limited number of regenerated seedlings and high diversity in flowering and fruit formation. In order to solve this problem, this study offer an alternative method by using tissue culture techniques. This study aimed to determine the effect of growth regulators on plantlet regeneration from bud slicing of pineapple cv. Tangkit. Four levels of 2.4-D (0.0, 0.001, 0.01 and 0.1 ppm) in combination with BA (0.0, 0.1, 1.0 and 10.0 ppm) were tested on solid MS medium. Cultures were incubated in total darkness for a week followed by transfer to 16-hour photoperiod. Results showed that explants treated with 2,4-D and/or BA succeeded in regenerating adventitious shoots. Average leaf number did not differ significantly among treatments (P = 0.60). Highest leaf number (2.99 ± 0.23) was obtained on medium with 0.01 ppm 2,4-D without BA, followed by 0.1 ppm 2,4-D without BA (2.85 ± 0.33). Meanwhile, roots were only formed on medium with 0.1 ppm 2.4-D without BA (4.2 ± 0.37 per shoot). Thus, complete plantlets were regenerated only on medium supplemented with 0.1 ppm 2,4-D without BA. The growth of plantlets was relatively uniform, and plantlet acclimatization succeeded 100% on Jiffy pots. The finding of optimum concentration of 2.4-D and BA in this study is important to develop standard protocol for in vitro propagation of pineapple cv. Tangkit. Thus, the benefit of producing seeds in large quantities and relatively uniform in growth is made possible through tissue culture technique.
Innovation of Suminten Edan Stories by Ketoprak Wahyu Manggolo Pati
Authors: Purnomo Sucipto Hadi , Astuti Tri Marhaeni , Irianto Agus Maladi
Published: January 2019

This research aims at discovering the innovation performed by artists of people’s theatre to the stories which have been a tradition and commonly known to the audience. This research uses a qualitative-descriptive approach, focusing on the performance of Sumonten Edan (SE) story by a ketoprak group Wahyu Manggolo Pati. In performing the story, despite being bound by the basic norms of performance known as pakem, Suminten Edan story is performed with some modifications to show innovations. These innovations include both the story and performance aspects.
Partial androgen insensitivity syndrome presenting as pubertal gynecomastia: clinical and hormonal findings and a novel mutation in the androgen receptor gene
Authors: Vaidyanathan Priya , Kaplowitz Paul
Published: January 2019

Pubertal gynecomastia is common, can be seen in 65% of the adolescent boys and is considered physiological. It is thought to be due to transient imbalance between the ratio of testosterone and estradiol in the early stages of puberty. It resolves in 1–2 years and requires no treatment. However, more persistent and severe pubertal gynecomastia is less common and can be associated with pathological disorders. These can be due to diminished androgen production, increased estrogen production or androgen resistance. We report a case of persistent pubertal gynecomastia due to partial androgen insensitivity syndrome (PAIS), classical hormone findings and a novel mutation in the androgen receptor (AR) gene.

Learning points:

Laboratory testing of follicle-stimulating hormone (FSH), leutinizing hormone (LH) and testosterone for pubertal gynecomastia is most helpful in the setting of undervirization.

The hormonal finding of very high testosterone, elevated LH and estradiol and relatively normal FSH are classical findings of PAIS.

Gynecomastia due to PAIS will not resolve and surgery for breast reduction should be recommended.
Urotensin II: an inflammatory cytokine
Authors: Sun Shui-lin , Liu Liang-ming
Published: January 2019

Urotensin II (UII) is a polypeptide molecule with neurohormone-like activity. It has been confirmed that UII is widely distributed in numerous organs of different animal species from fish to mammals, including humans. The UII receptor is orphan G-protein-coupled receptor 14, also known as UT. The tissue distribution of UII and UT is highly consistent, and their expression may be regulated by autocrine and paracrine mechanisms. In the body, UII has many physiological and pathophysiological activities, such as vasoconstrictor and vasodilatory actions, cell proliferation, pro-fibrosis, neuroendocrine activity, insulin resistance and carcinogenic and inflammatory effects, which have been recognized only in recent years. In fact, UII is involved in the process of inflammatory injury and plays a key role in the onset and development of inflammatory diseases. In this paper, we will review the roles UII plays in inflammatory diseases.
Acute restraint stress triggers progesterone withdrawal and endometrial breakdown and shedding through corticosterone stimulation in mouse menstrual-like model
Authors: Wang Shu-Fang , Chen Xi-Hua , He Bin , Yin De-Dong , Gao Hai-Jun , Zhao Hao-Qi , Nan Nan , Guo Shi-Ge , Liu Jian-Bing , Wu Bin , Xu Xiang-Bo
Published: January 2019

Stress impacts the reproductive axis at the level of the hypothalamus and the pituitary gland, which exert an effect on the ovary. Menstruation is regulated by the hypothalamic–pituitary–ovary (HPO) axis. However, the role of stress in menstruation remains unclear. The objective of this study was to explore the role of stress in endometrial breakdown and shedding, using the pseudopregnant mouse menstrual-like model. Female mice were mated with vasectomized males and labeled day 0.5, upon observation of a vaginal seminal plug. On day 3.5, decidualization was induced in pseudopregnant mice using arachis oil. On day 5.5, pseudopregnant mice with artificial decidualization were placed in restraint tubes for 3 h. The findings indicated that acute restraint stress resulted in the disintegration of the endometrium. While corticosterone concentration in the serum increased significantly due to restraint stress, follicle-stimulating hormone (FSH), luteinizing hormone (LH) and progesterone (P4) levels in the serum decreased significantly. An endometrial histology examination indicated that progesterone implants may rescue P4 decline caused by acute stress and block endometrium breakdown and shedding. In addition, mice were treated with metyrapone, an inhibitor of corticosterone synthesis, 1 h prior to being subjected to restraint stress. Interestingly, metyrapone not only inhibited stress-induced endometrium breakdown and shedding, but also prevented stress-induced reduction of P4, LH and FSH. Furthermore, real-time PCR and western blot showed that mRNA and protein expression of CYP11A1 (cytochrome P450, family 11, subfamily A, polypeptide 1) and steroidogenic acute regulatory protein (StAR), the two rate-limiting enzymes for progesterone synthesis in the ovary, decreased following acute stress. But metyrapone prevented the reduction of StAR expression induced by restraint stress. Overall, this study revealed that acute stress results in an increase in corticosterone, which may inhibit LH and FSH release in the serum and CYP11A1 and StAR expression in the ovary, which finally leads to the breakdown and shedding of the endometrium. These experimental findings, based on the mouse model, may enable further understanding of the effects of stress on menstruation regulation and determine the potential factors affecting stress-associated menstrual disorders.
Del dandy al esteta: el cultivo de la sensibilidad, entre lo individual y lo colectivo
Authors: Hernández Barbosa Sonsoles
Published: January 2019

Las figuras del dandy y el esteta, con sus características singulares, abanderaron en las urbes decimonónicas el intento de huida de una cotidianidad apegada a patrones y códigos convencionales de comportamiento. Para ello, ambas tipologías apostaron por el cultivo de una particular sensibilidad. En este artículo, nos adentraremos en las personalidades del dandy y el esteta para tratar de entender en qué consistió y a qué respondió esta sublimación de lo sensible. También revelaremos algunos de los rasgos que diferencian al dandy del esteta así como la relación de ambos con el elitismo. Finalmente, bajo este mismo prisma sociológico, indagaremos en las dinámicas que hay detrás del paso de la singularidad del dandy a la aparición de todo un movimiento como el esteticismo de finales del XIX.
Las transformaciones en el poder y su influencia en la pintura francesa en la primera mitad del siglo XVIII. La gubernamentalidad y la bóveda de la Banca Real de París de Antonio Pellegrini, 1720
Authors: Blanco Aparicio Jaime
Published: January 2019

El presente artículo reconstruye la bóveda que pintó Antonio Pellegrini para la Banca Real de París en 1720, a través de una descripción anónima recogida por Caylus y P.-J. Mariette. Ésta nos permite comprender la transformación del poder y su representación acontecida en Francia a principios del siglo XVIII, la cual hemos definido como paso de la Soberanía a la Gubernamentalidad, que condiciona el discurso pictórico de la Regencia, trastrocando el discurso alegórico versallesco definido en torno al cuerpo del soberano, a favor de la idea de gobierno, erigido sobre nuevos saberes como el económico.
In girum imus nocte et consumimur igni: Del laberinto al circuito. Algunas notas sobre el andar como práctica estético-políticca.
Authors: Valle Corpas Irene
Published: January 2019

La imagen del laberinto ha sido objeto de múltiples revisiones en el dominio artístico durante todo el siglo XX. Pero fue la década de los sesenta la que hizo de ella una figura esencial para numerosos teóricos y creadores que se negaban a seguir los preceptos del urbanismo dominante. A partir de la noción deleuziana de pliegue, el presente artículo pretende esclarecer las razones que motivaron el rescate de ciertos aspectos del arte Barroco y determinar cuál es su relación con el recurso a lo laberíntico y el andar performativo. Para finalizar, trataremos de situarnos en las últimas décadas de la centuria con el objetivo de comprobar qué fortuna ha tenido esta metáfora como mecanismo de actuación política.
La arquitectura institucional política en Galicia durante la Autarquía
Authors: Abelleira Doldán Miguel
Published: January 2019

Tras la Guerra Civil española y el consiguiente cambio de régimen político la arquitectura se convirtió en una herramienta transmisora de ideología y a la vez en un símbolo del poder. Esta relación se evidenció de un modo muy claro en las arquitecturas institucionales políticas. Las que se realizaron en Galicia no fueron una excepción a esa regla en ese momento indiscutida. A partir del estudio de una documentación inédita y desde una óptica disciplinar se analizan dichas arquitecturas que poseen una carga semántica indudable y que se han convertido en referentes urbanos en sus respectivas ciudades, adecuándose a los nuevos usos democráticos sin perder su carácter institucional.
Gerda Wegener (1885-1940), una danesa en París: retratos de una pareja singular y creación de una identidad transgénero
Authors: Ramos Frendo Eva María
Published: January 2019

El objetivo de nuestro ensayo es analizar la actividad como retratista de la danesa Gerda Wegener (1885-1940), cuya trayectoria artística se desarrolla entre Dinamarca, París y Marruecos. Ella fue muy solicitada por artistas y miembros de las altas clases sociales. No obstante, sus retratos más destacados fueron los que mostraron a su esposo, Einar Wegener, bajo el atuendo de su otro yo, Lili Elbe, clara manifestación de las identidades transgénero. Pero Gerda también trabajó como ilustradora en revistas, anuncios publicitarios y libros, tocó temas satíricos, picantes y de alto contenido erótico. Fue una artista pionera que no dejó indiferente a nadie ante sus creaciones. Hasta el momento era célebre por ser la esposa del primer transexual de la historia y pretendemos que sea su obra la que le de la fama y el reconocimiento que se merece.
Historia de una invención: realidad y ficción del supuesto autorretrato del Maestro Mateo en el Pórtico de la Gloria
Authors: Vigo Trasancos Alfredo
Published: January 2019

La historiografía decimonónica difundió la opinión de que la figura arrodillada que se encuentra en la parte posterior del parteluz del Pórtico de la Gloria, en la catedral de Santiago, era un retrato o representación del Maestro Mateo, añadiendo además que, en la cartela que lleva en su mano izquierda, aparecía escrita la palabra  “ARCHITECTUS”, hoy borrada. Sin duda se trata de una falsedad histórica que este artículo pretende demostrar, proponiendo asimismo una interpretación muy diferente del que, popularmente, se conoce también como “Santo dos Croques”.
Some remarks concerning Polish Japonisme movement from the Modernist Era
Authors: Pawłowska Aneta Joanna
Published: January 2019

Polish Japonisme, i.e. Japanese art inspirations in the work of the Polish painters and printmakers of the early period of modernism (the late 19th and early 20th centuries).The article will present well-known Polish artists such as Olga Bozna?ska, Julian Fa?at, Wojciech Weiss, Leon Wyczó?kowski, Satnis?aw Wyspia?ski as well as Jan Stanis?awski and his talented students. Juxtaposing works done by Polish artists of the Young Poland period with selected examples of Japanese ukiyo-e woodblock prints and silk paintings (done by such masters as: Hokusai, Hiroshige and Utamaro) as well sculptures and artistic handicrafts, I will demonstrate this phenomenon seen from the 21century perspective.  This new approach encourages the reader to make comparisons, to look – almost automatically – for similarities and differences between Polish and Japanese arts, and by revealing the clear and deep analogies between the two cultures, to engage in intercultural dialogue.Key words:Polish art, Japonisme, ukiyo-e prints.
Herramientas teóricas para la definición y análisis de las “candidaturas independientes” locales: nuevas posibilidades de estudio en el ámbito municipal español
Authors: Ureta García Miriam
Published: January 2019

Esta investigación nace con vocación de ofrecer herramientas teóricas que sirvan para definir, clasificar y analizar el fenómeno de las “candidaturas independientes”, con especial atención al caso español. Así, el primer objetivo de este trabajo es proponer un esquema de categorización integral que conecte las contribuciones de diferentes autores a la hora de clasificar en subtipologías realidades diversas derivadas de la categoría general de “candidaturas independientes”. El segundo objetivo es presentar evidencias empíricas a partir de las cuales se fundamentan las nuevas posibilidades de estudio de “candidaturas independientes” en la esfera municipal española. Mientras que, finalmente, el tercer objetivo persigue conocer los factores estructurales generales a partir de los cuales se puede comenzar a explicar por qué surge y aumenta en votos  la unidad de análisis de la investigación.
First record of the orchid bee Euglossa imperialis Cockerell, 1922 (Hymenoptera, Apidae, Euglossina) in Mato Grosso do Sul state, midwestern Brazil
Authors: Henrique Jessica Amaral , Sobreiro Ana Isabel , Alves-Júnior Valter Vieira
Published: January 2019

The occurrence of Euglossa imperialis Cockerell, 1922 is recorded for the first time in Mato Grosso do Sul, Brazil. This paper extends the distribution of the species by about 800 km west of the São Paulo state, its nearest record.
A new occurrence of Gomesa leinigii (Pabst) M.W. Chase & N.H. Williams (Orchidaceae) and new populations of Macradenia paraensis Barb.Rodr. (Orchidaceae) and Peperomia psilostachya C.DC. (Piperaceae) in São Paulo state, Brazil
Authors: Seidinger Letícia Chedid , Felipe Teixeira Wilton , Udulutsch Renata Giassi
Published: January 2019

We present the first record of Gomesa leinigii (Pabst) M.W. Chase & N.H. Williams in São Paulo state, Brazil, previously known only in the state of Paraná, extended its geographical distribution. We also document newly discovered populations of Macradenia paraensis Barb.Rodr. and Peperomia psilostachya C.DC. in São Paulo state, Brazil. Description, comments, conservation status, photographic figures and a distribution map of these species are presented.
Profile of pyoderma in dermatology outpatient departement at Sanglah General Hospital Denpasar, Bali-Indonesia period January 2016 until December 2017
Authors: Karna Ni Luh Putu Ratih Vibriyanti , Gotama Dewi , Sissy Sissy
Published: January 2019

Introduction: Pyodermas are infections in the epidermis, just below the stratum corneum or in hair follicles. It is most common in children, although it can also affect adults. Pyoderma often found in tropic areas. Pyoderma is caused by Staphylococcus, Streptococcus, or both. This study aimed to identify the profile of pyoderma in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Method: Study design using descriptive retrospective model, done by taking data from daily visit record in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Result: Pyodermas is one of the common skin problems observed in patients attending dermatology OPD. The number of new cases in pyoderma is 202 cases (7,32%), often found in males and 0-5 years age group (35,64%). The diagnosis of furuncle is the most finding type of pyoderma and the most commonly given therapy is a combination therapy of systemic antibiotics with topical. Co-amoxiclav is the most common drug that uses orally and fusidic acid as topical ointment.Conclusion: pyoderma remains as the most common skin infection in dermatology outpatient department at Sanglah General Hospital, Bali-Indonesia.
PENGEMBANGAN SOAL-SOAL KIMIA BERMUATAN NILAI-NILAI UNTUK MEMPERKOKOH KARAKTER SISWA SMA
Authors: Sulastri Sulastri , Rusman Rusman , Arifa Asria
Published: January 2019

Telah dilakukan penelitian pengembangan  soal-soal kimia materi hidrokarbon dan minyak bumi bermuatan nilai-nilai (Value based Questions-VBQs) untuk memperkokoh karakter siswa SMA. Penelitian ini bertujuan untuk menghasilkan soal-soal kimia SMA bermuatan nilai-nilai karakter. Nilai-nilai yang terdapat pada soal yang dikembangkan adalah  nilai-nilai: intelektual, spiritual, etika, estetika, sosial dan ekonomi. Penelitian ini menggunakan metode penelitian dan pengembangan melalui tahapan pendefinisian, analisis materi dan indikator (define), desain soal (design) dan pengembangan soal (develop). Subjek penelitian yaitu siswa SMAN 1 Banda Aceh kelas IX yang diambil secara purposive sampling dan jumlah siswa yang terlibat pada tahap diseminasi sebanyak 15 orang untuk melihat keberterimaan siswa terhadap soal. Soal yang telah dikembangkan divalidasi oleh pakar pendidikan kimia dan guru MGMP kimia kota Banda Aceh, hasilnya menunjukkan bahwa soal yang dikembangkan layak untuk diujicobakan pada siswa. Rata-rata hasil penilaian kelayakan soal sebesar 87%. Hasil tanggapan keberterimaan soal oleh peserta didik menunjukkan persentase sangat setuju sebesar 30%, setuju 50%, tidak setuju 20% dan sangat tidak setuju 0%. Berdasarkan hasil penelitian dapat disimpulkan soal-soal bermuatan nilai yang dikembangkan dapat diterima oleh guru, layak diaplikasikan dan dipergunakan untuk mengukur hasil belajar siswa. Perlu penelitian lanjutan untuk mengembangkan soal-soal bermuatan karakter bagi materi-materi ajar mata pelajaran kimia lainnya.
PENERAPAN MODEL PEMBELAJARAN INKUIRI TERBIMBING UNTUK MENINGKATKAN KETERAMPILAN PROSES SAINS SISWA PADA KONSEP LARUTAN ELEKTROLIT DAN NONELEKTROLIT
Authors: Dijaya Arisna Oktavia , Pitasari Ratih , Kurniasih Siti
Published: January 2019

Penelitian ini bertujuan untuk mendeskripsikan aktivitas siswa untuk setiap siklus pada proses pembelajaran inkuiri terbimbing, kinerja siswa untuk setiap siklus sesuai tahapan inkuiri terbimbing, dan keterampilan proses sains untuk setiap siklus dengan model inkuiri terbimbing. Metode penelitian yang digunakan adalah penelitian tindakan kelas. Subjek penelitian 35 siswa kelas X IPA-4 SMAN 10 Bandung. Instrumen yang digunakan adalah deskripsi pembelajaran, lembar kerja siswa, format penilaian aktivitas siswa, guru, aspek psikomotor siswa, dan tes evaluasi keterampilan proses sains. Data yang diperoleh diolah menggunakan statistik deskriptif. Penerapan model pembelajaran inkuiri terbimbing dilaksanakan sesuai deskripsi pembelajaran. Hasil penelitian menunjukkan penerapan model pembelajaran inkuiri terbimbing pada konsep larutan elektrolit dan nonelektrolit untuk meningkatkan keterampilan proses sains terimplementasikan dengan baik. Jumlah rata-rata aktivitas siswa selama pembelajaran mengalami peningkatan pada setiap siklusnya. Pada siklus I nilai rata-rata aktivitas siswa sebesar 86,4 (sangat baik) dan siklus II 91 (sangat baik). Melaksanakan pekerjaan LKS dengan benar untuk setiap siklus sehingga pembelajaran inkuiri terbimbing pada konsep larutan elektrolit dan nonelektrolit mengalami peningkatan. Nilai rata-rata siklus I sebesar 70 (baik) dan siklus II sebesar 75 (baik). Peningkatan keterampilan proses sains siswa pada siklus I dan II dengan nilai rata-rata siklus I yaitu 67 (cukup) dan siklus II yaitu 70 (baik).
RESÍDUO DE GESSO NA RECUPERAÇÃO DE SOLO SALINO-SÓDICO PROVENIENTE DE PERÍMETRO IRRIGADO DO SEMIÁRIDO BRASILEIRO
Authors: Cavalcanti Natália De Souza , Rolim Mário Monteiro , Santos Júnior José Amilton , Barros Maria de Fátima Cavalcanti , Pedrosa Elvira Maria Regis
Published: January 2019

A destinação dos resíduos de gesso gerados pela construção civil e a análise do seu potencial de aproveitamento na recuperação de solos salino-sódico é relevante quanto a mitigação de impactos ambientais. Portanto, a propositura do presente trabalho foi comparar o efeito da incorporação prévia de Ca[SO4]•2H2O na forma de gesso mineral e resíduo de gesso oriundo da construção civil, associado a aplicação semanal e intermitente de quatro lâminas de lixiviação, equivalentes a 1; 2; 3 e 4 vezes o volume de poros, sobre os trocáveis e solúveis de um Neossolo Fluvico salino-sódico oriundo do perímetro irrigado de Ibimirim-PE e disposto em colunas de solo. O delineamento experimental adotado foi o inteiramente casualizado, em arranjo fatorial, 2×4, com cinco repetições, totalizando 40 unidades experimentais. Considerando-se os valores iniciais dos cátions trocáveis e solúveis, da condutividade elétrica, do pH, do percentual de sódio trocável e da razão de adsorção de sódio, verificou-se, após o experimento, que o processo de recuperação do Neossolo Fluvico salino-sódico utilizando resíduo de gesso da construção civil como corretivo químico apresentou resultados similares aos obtidos utilizando-se o gesso mineral, quando associado a aplicação de uma lâmina de lixiviação equivalente a 3 vezes o volume de poros.
Kontinuitet og fornyelse i teatret
Authors: Trolie Tor Bastiansen
Published: January 2019

Denne artikkelen viser gjennom en rekke oppsetninger av Gengangere på Den Nationale Scene hvordan teaterforestillingen blir stadig mer selvstendig og gradvis løsrevet fra tekstgrunnlaget. Teatret blir skapende ut fra sine egne historiske og estetiske forutsetninger som kommer til syne i selve forestillingen.