bluuebunny/crossref_metadata_2025 huggingface dataset:
Tingkat Efisiensi Pada Usahatani Padi Sawah di Desa Noelbaki, Kabupaten Kupang, NTT
Authors: Suek Johanna , Ritan Yosefa Bernadina Nitit , Pudjiastuti Sondang
Published: November 2021

Efisiensi dapat dicapai  dengan meminimalkan sumber daya yang dibutuhkan untuk memproduksi output tertentu, atau memaksimalkan output yang dihasilkan dari sumber daya tertentu. Penggunaan sumberdaya yang efisien dapat meningkatkan produktivitas. Seberapa efisienkah penggunaan sumberdaya pada usahatani padi sawah, diinvestigaasi melalui studi yang bertujuan mengestimasi faktor-faktor produksi yang mempengaruhi usahatani padi sawah dan mengukur tingkat efisiensinya. Penelitian dilaksanaan di Desa Noelbaki Kecamatan Kupang Tengah Kabupaten Kupang. Penentuan populasi secara secara sengaja dengan pertimbangan petani pemilik lahan sawah. Pengambilan contoh secara acak sebanyak 60. Analisis  data fungsi produksi stochastic frontier Cobb-Douglas, dan fungsi biaya Cobb-Douglas Stochastic Frontier untuk memperoleh nilai efisiensi ekonomi sedangkan efisiensi alokatif merupkan hasil bagi dari  efisiensi teknis terhadap efisiensi ekonomi. Hasil studi menunjukkan bahwa faktor produksi luas lahan, benih, pupuk, tenaga kerja berpengaruh nyata terhadap produksi padi sawah sedangkan faktor produksi pestisida tidak berpengaruh nyata. Penggunaan input faktor pada usahatani padi sawah dapat dikatakan cukup efisien secara teknis dan ekonomi dengan nilai rata-rata masing-masing masing sebesar 0,81±0,11 dan 0,84±0,15. Sedangkan efisiensi alokatif sangat efisien dengan nilai rata-rata sebesar 0,99±0,21.
1982 ANAYASASINA GÖRE YASAMA ORGANI ÜYE SAYISI VE YASAMA ORGANI ÜYE SAYISINDA MEYDANA GELEN DEĞİŞİKLİKLER
Authors: YILMAZ İbrahim
Published: November 2021

1982 Anayasasının Türkiye Büyük Millet Meclisi üye sayısı hakkında hüküm içeren 75. maddesi, 16 Nisan 2017 tarihinde kabul edilen Anayasa değişikliği referandumu ile birlikte üçüncü kez değiştirilmiş oldu. Bu çalışma, 1982 Anayasasının yasama organı üye sayısını belirleyen 75. maddesinin değiştirilişini üç temel konu başlığı altında ele almaktadır. İlk olarak, Türkiye’de yasama organı üye sayısı değişiklikleri, anayasa değişikliği teklifi kanununun madde gerekçeleri, Anayasa Komisyonu Raporları ve Türkiye Büyük Millet Meclisi Genel Kurul görüşmeleri ışığında değerlendirilmektedir. İkinci olarak, Türkiye’deki yasama organı üye sayısı diğer OECD ülkelerinin yasama organı üye sayıları ile küpkök yasası dikkate alınarak mukayese edilmektedir. Son olarak, milletvekili sayısının 550’den 600’e çıkarılmasının seçim çevrelerine etkileri üzerinde durulmaktadır.
Pengaruh Kemandirian Belajar Dan Kemampuan Komunikasi Matematis Terhadap Hasil Belajar Matematisa Siswa Kelas XI IPA Di SMA Negeri 1 Kerinci
Authors: Zahara Zahara
Published: November 2021

Penelitian ini memiliki tiga tujuan yaitu 1) untuk mengetahui pengaruh secara parsial kemandirian belajar terhadap hasil belajar matematika siswa kelas XI IPA di SMA Negeri 1 Kerinci; 2) untuk mengetahui pengaruh secara parsial kemampuan komunikasi matematis terhadap hasil belajar matematika siswa kelas XI IPA di SMA Negeri 1 Kerinci; dan 3) untuk mengetahui pengaruh secara simultan kemandirian belajar dan kemampuan komunikasi matematis terhadap hasil belajar matematika siswa kelas XI IPA di SMA Negeri 1 Kerinci. Penelitian ini menggunakan metode penelitian kuantitatif dengan dengan jenis pendekatan penelitian survey, yang menjadi populasinya adalah siswa kelas XI IPA di SMA Negeri 1 Kerinci yang berjumlah 75 siswa. Sampel dalam penelitian ini diambil dari jumlah populasi melalui teknik pengambilan sampel dengan menggunakan random sampling, Untuk menghitung sampel penelitian dari populasi tersebut, peneliti menggunakan pedoman penentuan sampel yang dikembangkan dari rumus Slovin dengan taraf tingkat kesalahan 10% sehingga sampel dalam penelitian ini sebanyak 43 siswa. Instrumen yang digunakan dalam penelitian ini berupa angket kemandirian belajar (X1) dan kemampuan komunikasi matematis (X2) dengan skala likert untuk mengukurnya, serta hasil belajar matematika beardasarkan hasil belajar setelah proses belajar mengajar pada mata pelajaran matematika berakhir. Data dianalisis menggunakan analisis regresi linier berganda bantuan program SPSS for windows versi 25. Hasil penelitian ini bahwa 1) terdapat pengaruh secara parsial kemandirian belajar terhadap hasil belajar matematika siswa kelas XI IPA SMA Negeri 1 Kerinci ditandai dengan nilai t hitung > t tabel (3.290 > 1.683) dan siginifikansi 0,034 < 0,05; 2) terdapat pengaruh secara parsial kemampuan komunikasi matematis terhadap hasil belajar matematika siswa kelas XI IPA SMA Negeri 1 Kerinci ditandai dengan nilai t hitung > t tabel (-2.375 > 1.683) dan siginifikansi 0,019 < 0,05; 3) tidak terdapat pengaruh secara simultan antara kemandirian belajar dan kemampuan komunikasi matematis terhadap hasil belajar matematika siswa kelas XI IPA SMA Negeri 1 Kerinci ditandai dengan nilai F hitung < F tabel 1.842< 3.214) dan siginifikansi 0,089 > 0,05. Besarnya pengaruh kemandirian belajar dan kemampuan komunikasi matematis terhadap hasil belajar matematika siswa kelas XI IPA SMA Negeri 1 Kerinci tergolong lemah yaitu sejumlah 21,4% dengan sisa 78,6% dipengaruhi oleh faktor lain di luar penelitian.
GAME EDUKASI PUZZLE RUMAH ADAT TRADISIONAL INDONESIA BERBASIS ANDROID
Authors: Yunanto Dyan
Published: November 2021

Puzzle games are a way or style in the process of early childhood learning that is more suitable to increase children's learning interest so that the learning process feels more fun, the problem that arises is how to introduce and educate about traditional Indonesian traditional home culture so that the younger generation can get to know and preserve traditional Indonesian culture. To overcome this problem, a game is made that can introduce and educate about traditional Indonesian traditional house culture. While the programming language used in building games is constrcut2. The results of implementation and trials conducted by researchers, it can be concluded that traditional Indonesian traditional house puzzle education games can recognize and educate indonesia's most traditional culture, especially traditional house culture.
Dr. Matthew C. Larsen
Authors: Berbey Alvarez Aranzazu
Published: November 2021

Matthew C. Larsen es el Director del Instituto Smithsonian de Investigaciones Tropicales, con sede en la Ciudad de Panamá, Panamá. El Instituto promueve la comprensión de la naturaleza tropical y su importancia para el bienestar humano, capacita a los estudiantes para realizar investigaciones en los trópicos y promueve la conservación al aumentar la conciencia pública sobre la belleza y la importancia de los ecosistemas tropicales. Además de sus científicos residentes, las instalaciones del Instituto son utilizadas anualmente por unos 1.300 científicos visitantes, becarios y pasantes pre y postdoctorales de instituciones académicas y de investigación que provienen de una cuarta parte de todas las naciones de la Tierra. De 2010 a 2014, el Dr. Larsen fue Director Asociado del Servicio Geológico de EE. UU. Para el Cambio Climático y del Uso de la Tierra, donde dirigió programas científicos centrados en el cambio climático, el cambio del uso de la tierra y una evaluación de secuestro de carbono ecológico nacional. Además, el Dr. Larsen administró el programa satelital Landsat y el Centro Nacional de Ciencia del Cambio Climático y la Vida Silvestre. De 2005 a 2014, el Dr. Larsen dirigió los programas de Recursos Hídricos del Servicio Geológico de EE. UU. Y se desempeñó como Presidente del Comité Nacional de EE. UU. Para el Programa Hidrológico Internacional de la UNESCO. Las más de 90 publicaciones de Larsen están relacionadas con los peligros naturales, los recursos hídricos, el cambio climático, los servicios de los ecosistemas y la geología marina. El Dr. Larsen obtuvo un B.S. en Geología de Antioch College, Yellow Springs, Ohio, y un doctorado en Geografía en la Universida.
Impacto del recurso humano al implantar un sistema de gestión de inocuidad alimentaria en pequeñas y medianas empresas en Panamá
Authors: Cortés Damarys , Chue de Pérez Juana Ramos , Tejedor Wedleys
Published: November 2021

Con el fin de encontrar una alternativa eficiente para la implantación de un sistema de gestión de inocuidad alimentaria (SGIA) que sea afín a las pequeñas y medianas empresas (pymes) de alimentos de nuestro país, se realizó un estudio de caso y una encuesta a 100 pymes de alimentos en Panamá. Se propone un modelo metodológico usando tres pilares básicos: conceptos mínimos de la gestión del recurso humano, una herramienta de la ingeniería de proyectos y las buenas prácticas higiénicas (BPH) como parte de todo SGIA. Se presenta el desarrollo del primer pilar, en el cual se puntualiza el concepto de cultura de inocuidad como un componente clave de los planes estratégicos de implantación de sistemas de gestión. Como parte del modelo, se evaluaron los principales retos que confronta el personal y se identificaron los requisitos mínimos con que debe contar un Departamento de Recursos Humanos, los cuales, una vez adecuados permiten a las empresas alcanzar el éxito en materia de calidad e inocuidad.
Confidencialidad de datos mediante el grabado de códigos QR cifrados
Authors: Padrón-Godínez Alejandro , Prieto Meléndez Rafael , Treviño-Palacios Carlos Gerardo
Published: November 2021

La combinación de mecanismos de seguridad mediante Criptografía y Esteganografía trae consigo aumentar el nivel de seguridad en el diseño de nuevos dispositivos. En este trabajo implementamos una mezcla de sistemas de seguridad para la confidencialidad de datos, en el diseño de una marca de agua que contenga un código QR cifrado mediante el algoritmo “Data Encryption Standard” de 8 bytes. Además de la generación de una rejilla dada por una matriz de puntos del propio código QR que produce un patrón de difracción y su correspondiente patrón entrelazado. Se presentan los resultados de las marcas de agua o patrones de difracción en imágenes digitales. Éstas también podrán ser observadas cuando se graban en placas de vidrio portables, mediante un proceso de daño óptico automatizado. Así tenemos identificadores ópticos de control de acceso con confidencialidad de datos. La aportación de este artículo es la integración de varias disciplinas de las ciencias e ingenierías para el desarrollo tecnológico de aplicaciones de uso diario en sistemas de seguridad.
Psychiatric Co-Morbidity and Substance Use Correlated with Medication Adherence Among People Living with HIV (PLWHIV) Attending the Virology Clinic of the University of Port Harcourt Teaching Hospital (UPTH)
Authors: A. K Nkporbu , O.A Ayodeji
Published: November 2021

HIV infection is an endemic communicable chronic disease, of enormous public health concern worldwide particularly, Sub-Saharan African. Substance use and associated psychiatric co-morbidity among the sufferers may affect medication adherence. The aim of this study, therefore, was to determine the effect of psychiatric comorbidity and substance use on medication adherence among people living with HIV at the University of Port Harcourt Teaching Hospital. A cross-sectional study was conducted among 230 Subjects Living with HIV. Sociodemographic questionnaire was used. A structured questionnaire was used to assess use of psychoactive substances. Psychiatric co-morbidity was assessed using the GHQ-12 in conjunction with the DSM 5. The Medication Adherence Rating Scale (MARS) was used to assess medication adherence. Data was analysed using the SPSS version 20. The prevalence of psychological co-morbidity among PLWHIV was 30.6%. Alcohol use disorders was the highest with 73 (31.7%), followed by cigarette smoking 38 (16.5%) while nicotine snuffing was the least with 1 (0.4%). Of the 43 (18.7%) with poor medication adherence, 31 (15.2%) had psychiatric co-morbidity, 26 (11.3%) had substance use, 25 (10.8%) had both psychiatric and substance use co-morbidity while 19 (8.2%) had none (p=0.004). Psychological co-morbidity and substance use are prevalent among PLWHIV, and may affect medication adherence.
Intrabases divergences in the mHealth era: a drug interaction investigation in an infectious-diseases hospital setting
Authors: Souza Roberta , Silva Pedro Ivo da , Cascao Paulo César , Sousa Clarissa Alencar , Lopes Angela Ferreira
Published: November 2021

Introduction: Information on potential drug interactions (PDI) are obtained from databases available on the web or through mobile healthcare applications (mHealth), and can prevent unfavorable clinical outcomes for patients. This study compared PDI information available in Micromedex® drug interaction checker, its web version and its mHealth app. Method: A cross-sectional study realized based on a retrospective review of drug prescriptions in a reference hospital in infectology in the Midwest Region of Brazil, 2018. We selected all prescriptions containing two or more drugs. Drugs were classified according to the first level of the Anatomical Therapeutic Chemical (ATC) classification, according to the route of administration and the number of drugs prescribed. PDIs were classified according to the severity system and four-level evidence classification system. Results: This study selected 72 patients, predominantly male, median age of 38 years, average length of stay of 15.8 days, and most diagnosed with HIV/AIDS. The most frequently prescribed anatomical groups according to ATC were digestive system and metabolism (22.1%) and general anti-infectives for systemic use (21.6%). The average number of drugs per prescription was 10.8 (SD±6.7). The Micromedex® mHealth app found 381 PDIs while its web version detected 502 PDIs, with an average of 5.3 and 7.0 and frequency of 61.1% and 72.2%, respectively. According to the severity classification in mHealth and web versions, the following stood out, respectively: 221 and 321 severe; 139 and 149 moderate. The majority (>65%) of identified PDIs had their documentation classified as reasonable. Conclusion: Digital tools although they aid decision-making, are not unanimous and consistent in detecting such interactions.
Energia Eólica: Identificação e hierarquização dos riscos associados a projetos de investimento
Authors: Ono Elizabeth Mayumi , Rosário João Maurício , Freitas Andrey Pimentel Aleluia , Santos João Alberto Neves dos
Published: November 2021

O conceito de desenvolvimento sustentável faz com que os investimentos, em tempos de crise econômica, sejam relacionados a aspectos ambientais, sobretudo os que contemplam fontes de energia renováveis. Nesse contexto, por sua característica física e climática amplamente favorável, o Brasil apresenta elevado potencial para a exploração de fontes de energias naturais alternativas. Nessa linha, tais questões justifiquem o crescimento recente de projetos dedicados à geração de energia eólica no Brasil. Não obstante, apesar dos benefícios amplos contemplados por projetos no setor, os elevados níveis de incerteza podem representar obstáculos aos investidores. Assim, por meio de uma abordagem prévia dos riscos associados a projetos de investimento em fontes renováveis de energia eólica, pode-se identificar uma estrutura crítica que venha a contribuir com a visão crítica dos investidores, proporcionando maiores níveis de segurança às suas intenções. Dessa forma, buscou-se identificar os principais fatores de riscos associados à fonte geradora de energia eólica, destacados na literatura. Em seguida, a partir da elaboração de uma Survey, um questionário foi aplicado em uma amostragem não probabilística, caracterizada por profissionais e especialistas atuantes no setor. Os dados obtidos foram avaliados através da análise multivariada, cujo objetivo foi desenvolver um referencial crítico para auxiliar projetos de investimento, planejamento e gestão, onde os resultados identificaram 34 fatores de risco associados a fontes de energia eólica no Brasil, que foram hierarquizados, conforme os graus de impacto. Em ordem decrescente, destacam-se: burocracia; risco país; licenças ambientais; riscos contratuais e riscos regulatórios.
Biological potential and microencapsulation of Cinnamomum cassia essential oil as an alternative for pest control in stored maize
Authors: Minozzo Mariane , Steffens Juliana , Backes Geciane Toniazzo , Paroul Natalia , Cansian Rogerio Luis
Published: November 2021

This study proposes a review of biological potential of cinnamon (Cinnamomum cassia) essential oil with a focus on microencapsulation as an alternative to control the occurrence of pests in stored maize grains. Due to the demands on corn productivity, there is the need to improve grain storage processes and conditions, since that in this stage there are quantitative and/or qualitative losses, mainly due to the maize weevils (Sitophilus zeamais) and the incidence of mycotoxin-producing fungi (Penicillium crustosum, Alternaria alternata and Aspergillus flavus). The control of these pests is usually carried out with chemical insecticides, which can leave toxic residues in the grain. Therefore, the microencapsulation of essential oils appears as a promising alternative, considering the volatility of aromatic compounds, which are largely responsible for the activity against pests.
Revisão do kit básico de medicamentos para cirurgias de descompressão do túnel do carpo: proposta para melhorar a economia e a segurança do paciente
Authors: Silva Carla Neves da , Souza Juliana Batista de , Camuzi Ranieri Carvalho
Published: November 2021

Objetivo: propor a adoção de um kit de medicamentos específico para procedimentos cirúrgicos de descompressão do túnel do carpo, para substituir o kit farmacoterapêutico básico atualmente utilizado. Métodos: trata-se de projeto de desenvolvimento experimental envolvendo observação direta, levantamento de dados administrativos, estudo de evidências científicas e comparação econômica para propor o novo kit. Resultados: a observação direta indicou que os procedimentos adotados por vezes divergiam daquelas baseadas em evidências científicas; o perfil de utilização de medicamentos demonstrou que o kit atual é subutilizado e favorece o uso irracional de medicamentos; conhecendo-se o perfil de uso e as evidências científicas, foi possível propor um novo kit mais econômico, que permite mitigar o uso irracional e contribui para as estratégias de segurança do paciente. Conclusão: a adoção do novo kit proposto pode trazer benefícios à instituição tanto pela economia quanto pela contribuição para melhores resultados assistenciais e maior segurança do paciente.
Treinamento em primeiros socorros com alunos do ensino regular: relato de experiência
Authors: Campelo Camila Isnaide Pinheiro , Campelo Davi Pinheiro , Sousa Maria Rita Dias , Gois Lucas Costa de , Silva Sabrina Brenda Castelo Branco , Duarte Palloma Tamy Ferreira
Published: November 2021

Objetivo: apresentar um relato sobre a experiência vivida por graduandos em enfermagem ante a educação em saúde sobre primeiros socorros para alunos de ensino regular. Metodologia: Estudo descritivo, fundamentado em um relato das experiências vivenciadas por graduandos em enfermagem durante a execução de um projeto de iniciação científica da Universidade Estadual do Piauí. Desenvolvido em uma escola de tempo integral, no período de agosto a outubro de 2019, com amostra de 34 voluntários. Consistiu-se na avaliação da eficácia do treinamento, por meio aplicação de pré e pós-teste, seguido de ações educativas com aulas expositivas e dialogado, sucedidas de momentos práticos, onde os participantes eram colocados em situações hipotéticas e precisavam intervir. Resultados e discussão: Notou-se o potencial de disseminação de informações que os alunos possuíam facilitando, desta forma, a propagação dos cuidados iniciais prestados a uma vítima de acidente ou mal súbito. Conclusão: Afirma-se que os aprendizados e experiências alcançadas foram inestimáveis para os autores da pesquisa.
Fisioterapia aquática na redução da dor e melhora da qualidade de vida de idosos com osteoartrite de joelho: uma revisão sistemática
Authors: Oliveira Maria Clara Sousa , Veras Walyssandra Jasmile Campos , Ventura Patrícia Lima
Published: November 2021

A osteoartrite é uma disfunção musculoesquelética comumente insidiosa, gradativa e lenta, que se caracteriza pelo desgaste da cartilagem articular e por alterações ósseas. A fisioterapia aquática tem grande relevância no tratamento de pacientes com osteoartrite de joelho, diminuindo a dor e contribuindo para uma melhora significativa na qualidade de vida. O objetivo desse estudo, é revisar sistematicamente a efetividade da fisioterapia aquática na redução da dor em pacientes e melhora da qualidade de vida em idosos com osteoartrite de joelho. Sendo uma revisão sistemática de ensaios clínicos randomizados, analisados por dois revisores independentes, conforme recomendado pela plataforma Prisma nas bases de dados PubMed, PEDro e CENTRAL. Foram incluídos estudos originais utilizando a Fisioterapia Aquática na redução da dor e melhora da qualidade de vida em pacientes idosos com OA de joelho. A escala PEDro foi usada para analisar a qualidade metodológica e análise de risco de viés. Foram incluídos cinco estudos. A Fisioterapia Aquática, interveio na diminuição da dor e melhora da qualidade de vida quando comparado com outros métodos de intervenção aplicados em pacientes idosos com OA de joelho. Conclui-se que a Fisioterapia Aquática é uma opção eficaz para a osteoartrite de joelho, reduzindo os níveis de dor e aumento da qualidade de vida dos idosos.
Sexualidade infantil no contexto escolar: um desafio aos educadores
Authors: Soares Nandra Martins , Rufato Fabrício Duim , Rossetto Elisabeth
Published: November 2021

O objetivo deste estudo é entender quais as dificuldades enfrentadas pelos professores da educação infantil acerca da sexualidade no contexto escolar. Como recursos metodológicos, utilizou-se a abordagem qualitativa por meio de uma pesquisa de campo, com a aplicação de uma entrevista semiestruturada. Participaram da pesquisa cinco educadoras de um Centro Municipal de Educação Infantil (CMEI) do Município de Foz do Iguaçu – PR. Os dados foram analisados à luz da análise de conteúdo. A partir dos resultados, compreendeu-se que as professoras da educação infantil enfrentam dificuldades relacionadas às manifestações sexuais dos alunos, uma vez que, a falta de formação acadêmica e continuada destes profissionais, causa sentimento de insegurança frente a esta temática. Outra dificuldade enfrentada pelas educadoras está relacionada ao âmbito familiar da criança, visto que há grande resistência em falar e discutir sobre a sexualidade, o que se torna uma barreira na abordagem desse tema no contexto educacional. Desse modo, considera-se que a consolidação de discussões em espaços acadêmicos, a implementação de disciplinas e técnicas interventivas nas grades curriculares dos cursos que se propõem formar professores; assim como o aprofundamento no conhecimento do desenvolvimento infantil; e investimentos na formação continuada são ações necessárias para a construção de práticas no estudo sobre a sexualidade infantil.
Os riscos associados pelo uso não orientado de anabolizantes hormonais
Authors: Souza Denise Santos de , Souza Ederson Ferreira de , Pereira Swemy Oliveira
Published: November 2021

Introdução: A testosterona, o chamado hormônio masculino, é o andrógeno mais importante do corpo. Nos homens, a maior parte da testosterona é produzida nos testículos pelas células de Leydigin. Nas mulheres, os níveis de testosterona são muito mais baixos do que nos homens. No entanto, também tem um efeito importante no corpo feminino. A regulação hormonal da testosterona é mantida e controlada pelo eixo hipotálamo-hipófise-gônada. Objetivo: Evidenciar os riscos associados ao uso não orientado dos esteroides anabolizantes andrógenos para fins de hipertrofia muscular. Métodos: Refere-se a uma revisão sistemática, com o uso da técnica Preferred Reporting Items for Systematic Reviews and Meta-analyses (Prisma). A pesquisa bibliográfica foi realizada nas bases de dados: Medline (via PubMed), Scientific Electronic Library Online (Scielo) e na Biblioteca Virtual da Saúde (BVS), publicados entre 2014 e 2021 com objetivos exploratórios e abordagem qualitativa. Utilizou-se como descritores: esteroides anabolizantes androgênicos e testosterona, esteroides anabolizantes androgênicos e uso indiscriminado, esteroides anabolizantes androgênicos e efeitos adversos, uso indiscriminado e testosterona, efeitos adversos e testosterona. Resultados: Inicialmente selecionou-se 56 estudos nas bases de dados PUBMED, Scielo e BVS, após uma leitura mais detalhada elegeu-se 9 artigos utilizados nesse artigo. Como resultado do uso de andrógenos a longo prazo, os testículos podem ser significativamente reduzidos. Conclusões: Os efeitos negativos do uso de anabolizantes esteróides não desaparecem totalmente após a suspensão do seu uso, entre os efeitos indesejáveis como o risco de acometimento de doenças cardiovasculares, masculinazação em mulheres, hipertrofia muscular e lesões hepáticas entre outras.
International Journal of Engineering Applied Sciences and Technology, 2021 Vol. 6, Issue3, ISSN No. 2455-2143, Pages 36-44Published Online July 2021 in IJEAST (http://www.ijeast.com)36AN EMPIRICAL STUDY ON QUALITY OF EDUCATION:A CASE STUDY IN PRIMARY SCHOOLS IN WANGDUEPHODRANG DISTRICT,BHUTAN
Authors: Waiba Phurba Sonam , Sherab Jigme , Hingmang Aita Raj
Published: November 2021

Since 1914 education in Bhutan has progressed by leaps and bounds, however, the quality of education system has alwaysbeen a matter of inquiry and onfrequent question. Hence, there havebeen numerous efforts to help improvethequality of education in the last decade. Also deriving inspiration from the His Majesty the King, Jigme Khesar Namgyel Wangchuck on the efforts to revamping education system in the country, the study was undertaken to understand the quality of education and educational services in the country through a case study in Wangduephodrang District. The study is an empirical quantitative analysis. It used the SERVQUAL instrument. The data was collected through randomly distributed questionnaires through a convenience sampling method. Sample size of 334 was determined using an online survey monkey tool.The data was analysedusing excel to obtain descriptive statistics and individual value data plot. Paired two sample t-test was also performed to compare means and to see the significant difference between expectation and perception of the services of each of the items and dimensions as a whole at hypothesized mean difference of zero,alpha value of 0.05. The average gap score is at -0.4 which means that the expectations have not been met and quality of education services is unsatisfactory. Similarly, differencesbetween the means of overall average and all the five dimensions are found to be statistically significant. Interesting to note that ASSURANCE and TANGIBILITY requireimmediate attention. Some of the key findings are lack of adequate teachers and staff, lack of educational and instructional materials,need to foster and widen student-teacher bondsand need to cultivate a sense of assurance. On the contrary, teachers/schoolshave been found to be very proactive in assisting
DYNAMIC ANALYSIS AND COMPARATIVE STUDY OF PLAN IRREGULAR (C-SHAPED) BUILDING WITH DIFFERENT TYPES OF BRACING SYSTEM
Authors: Abdul Wahab Abdul Wasey , Ullagaddi Dr. P. B.
Published: November 2021

When the multi-storied buildings are
constructed a suitable care should be taken while
designing, as they are subjected to lateral forces. The
behaviour of multi-story building depends upon either in
plan or in vertical direction i.e, elevation, is considered as
one of the main causes of failure during earthquakes.
Thus irregular structures, especially the structures which
are located in seismic zones are required a special
attention during analysis and design of structure. In this
study Plan irregular (C-shaped building) is considered to
carry out study. Bracing system is installed to provide
strength against lateral loading and the behaviour of the
structure in terms of base shear, story drift, stiffness and
the lateral displacements are observed. Three different
types of bracings X, V and Diagonal are installed in the
structure. Total 4 models are analysed for 7 story height
level, 4 Models are computed to determine the
performance of the structure. One MRF and three models
with different bracing system. And the best suitable
bracing system for this study. The method used for this
study is response spectrum method, to perform dynamic
analysis of the structure.
AN APPLICATION FOR THE DOCTORS+
Authors: Shukla Vishwam , Parikh Shreeya
Published: November 2021

Doctors+ is an application intended with the focal
goal of creating a convenient and reliable health care
system. It holds data integrity, effective communication,
reliable storage and relay of information among many of its
central objectives. Further integration with intelligent
systems allows it to provide an interactive and predictive
interface for the stakeholders involved.
HEADING CONTROL OF AUTOMATED GUIDED VEHICLES
Authors: Bhardwaj Abhishek , Anand Kshitij , Khasamwala Murtaza
Published: November 2021

With rapid developments in industry wide
automation control systems, there have been numerous
proposed design and control strategies as alternatives to
conventional methods. This term paper deals with the same
in the context of Automated Guided Vehicles (AGV’s) with
a review of the current literature for proposed design
improvements as well as trajectory control systems that can
improve productivity and reduce conflicts compared to
current methods. The results of these proposed methods are
also compared in contrast to each other to obtain holistic
view of the merits and demerits of the same. It is found that
a fuzzy logic based PID control is a definite upgrade over
conventional PID control systems and that the application of
LIDAR and Camera based technologies can help enable free
roaming AGV’s lending to increased robustness and
flexibility. For a control system consisting of a single AGV
and multiple processing stations, a genetic algorithm
enhanced centralized fuzzy logic control system is the most
optimal path planning algorithm whereas in the cases of
multiple robots, a dynamic priority allocated free roaming
AGVsystem with semi-decentralized control is found to be
much more efficient at simultaneously solving paths and
reducingconflicts with other robots in real time compared to
the purely centralized systems.
SHAPE MEMORY ALLOY ACTUATORS ARE USED TO CREATE A VARIABLE AREA JET NOZZLE FOR NOISE REDUCTION: A REVIEW
Authors: Chavan Shubham , Gujar Pratap
Published: November 2021

The real study details the design and
implementation of Shape memory alloy actuators to
produce a noise-reducing variable area jet nozzle. A
subscale design specification of a changeable area jet
nozzle was created using SMA actuators in an
asymmetrical design. Commercial transportation planes
must be quieter, cleaner, and more efficient, according to
the international community. The aviation industry is
reacting by developing new technology in order to achieve
those objectives. Changing the area of a commercial jet
engine's fan nozzle can result in substantial noise
reduction and reduced fuel economy. At takeoff and
approach, a bigger diameter reduces jet velocity, which
reduces noise. In cruise, adjusting the diameter to account
for variable Mach numbers, altitude, and other factors
helps optimise fan loading and minimise fuel consumption
and emissions. Boeing has tested a 20 percent area change
scaled variable area jet nozzle. At the nozzle exit, Shape
Memory Alloy actuators were utilised to place 12
interlocking panels. To maintain a range of consistent
diameters with variable flow circumstances and to alter
the diameter under constant flow conditions, a closed loop
control system was utilised. At each condition, acoustic
data was gathered using side line microphones, and flow
field measurements were taken using PIV at various crosssections. The design of a variable area nozzle is explained
in this work. The diameter of the nozzle and its influence
on acoustic performance are discussed. The effects of the
joints between the interlocking panels are seen in the flow
field data.
STUDY ON RISK MANAGEMENT PRACTICES ON PUBLIC BUILDING CONSTRUCTION PROJECT: IN CASE OF EASTERN WOLLEGA ZONE
Authors: Mebrate Ejeta Zelalem , M Zelalem , Kumar M Vignesh , Tadesse Getnet , Jaleta Biftu
Published: November 2021

The Construction Industry is embedded with
risky situations that affect construction projects and
therefore requires systematic processing to achieve
project objectives and ensure business sustainability (5).
This research work was tries to study the risk
management practice on public building construction
projects and aims to identify the level that use of risk
management practice especially in the public building.
The data collection method was a combination of
interview and questionnaire. Samples were purposively
selected from clients, consultants, and contractors
representatives who are now actively participating in
public building construction projects.
For this study, the data was collected using both primary
and secondary sources. Depending on the data that was
gathered from the respondent to test the level of
awareness, identifying the Risk that affect the
performance of public building construction project and
major risk management practice on public building
construction project are considered and the RII was used
to rank the factors. This data was analyzed using SPSS of
version 22 to perform descriptive statistics. A total of 75
questionnaires were targeted to be distributed and out of
those 50 which is 66.67% are successfully responded.
The finding from this study revealed that, about (52%) of
the project progress is lagging from the schedule.
Regarding the awareness of the risk management, (94%)
of the respondents where confirmed that they have
awareness of risk management ideologies and they are
confident enough to implement their knowledge while,
(6%) of them have no concept about the risk management.
The top five risks that affect the performance of
construction project have been identified and ranked.
Accordingly; market condition, unexpected inflation,
local taxes, inadequate production of raw materials, and
the economic condition of country are the top five
identified associated project risks.
STUDY ON STABILITY CONTROL OF COAL MINE TUNNEL EXCAVATED IN WEAK ROCK MASS IN INDONESIA
Authors: Pongpanya Phanthoudeth , Sasaoka2 Takashi , Shimada Hideki , Soysouvanh Vongsavanh
Published: November 2021

This paper focuses on the stability analysis and
support design of the coal mine tunnel excavated in weak
rock mass in an Indonesian underground coal mine
through numerical simulations using the FLAC3D
software. The PT Gerbang Daya Mandiri (GDM) coal
mine situated in Indonesia was selected as a mine site in
this study. According to the results of a series of numerical
simulations, the stability of the mine tunnel decreases by
increasing the depth and stress ratio. Ground control
problems, for example falling roof, sidewall collapse, and
floor heave are expected unless an appropriate support
system is anticipated. Three support systems, including
friction rockbolt, steel arch, and shotcrete are discussed as
methods to stabilize the roof and sidewalls of the mine
tunnel. From the simulated results, the steel arch is
considered to be the most effective support method when
compared with other support systems. The steel arch
which is installed with closer space and larger crosssection delivers a better stability control to the roof and
sidewalls of the mine tunnel. Although the stability of the
roof and sidewalls of the mine tunnel can be maintained
effectively by the steel arch support, the occurrence of
floor heave is expected when the mining depth is increased.
To control the floor stability of the mine tunnel, three
techniques by applying cablebolt, invert-arch floor, and
grooving method are therefore investigated and discussed.
Based on simulated results, the heaving of the floor is well
controlled after the cablebolt, invert-arch floor, and
grooving methods are applied. Nevertheless, it is found
that controlling the floor heave by cablebolt support could
be the most suitable method comparing with other support
systems in terms of the installation process, providing flat
and safe working conditions of the floor, and economy.
Additionally, the cablebolt with closer row space and
longer length works more effectively to control the heaving
problem of the floor.
Keyword
Preparation and Characterization of Chinese Leek Extract Incorporated Cellulose Composite Films
Authors: Zeng Qiying , Xiao Naiyu , Zhang Xueqin , Luo Wenhan , Xiao Gengshen , Zhai Wanjing , Zhong Le , Lan Bifeng
Published: November 2021

This study aimed to prepare microcrystalline cellulose (MCC) films with good mechanical properties via plasticization using a Chinese leek (CL, Allium tuberosum) extract. The microstructure, crystal structure, mechanical properties, barrier ability, and thermal properties of the films were investigated. The chemical structure analysis of CL extract showed the existence of cellulose, lignin, and low-molecular-weight substances, such as polysaccharides, pectins, and waxes, which could act as plasticizers to enhance the properties of MCC:CL biocomposite films. The results of scanning electron microscopy and atomic force microscopy analyses indicated the good compatibility between MCC and CL extract. When the volume ratio of MCC:CL was 7:3, the MCC:CL biocomposite film exhibited the best comprehensive performance in terms of water vapor permeability (2.11 × 10–10 g/m·s·Pa), elongation at break (13.2 ± 1.8%), and tensile strength (24.7 ± 2.5 MPa). The results of a UV absorption analysis demonstrated that the addition of CL extract improved the UV-shielding performance of the films. Therefore, this work not only proposes a facile method to prepare MCC films with excellent mechanical properties via plasticization using CL extract but also broadens the potential applications of MCC films in the packaging area.
Sustained Release of VEGF to Promote Angiogenesis and Osteointegration of Three-Dimensional Printed Biomimetic Titanium Alloy Implants
Authors: Li Youbin , Liu Yuzhe , Bai Haotian , Li Ronghang , Shang Jing , Zhu Zhengqing , Zhu Liwei , Zhu Chenyi , Che Zhenjia , Wang Jincheng , Liu He , Huang Lanfeng
Published: November 2021

Tumor resection and treatment of trauma-related regional large bone defects have major challenges in the field of orthopedics. Scaffolds that treat bone defects are the focus of bone tissue engineering. 3D printing porous titanium alloy scaffolds, prepared via electron beam melting technology, possess customized structure and strength. The addition of a growth factor coating to the scaffold introduces a specific form of biological activation. Vascular endothelial growth factor (VEGF) is key to angiogenesis and osteogenesis in vivo. We designed a porous titanium alloy scaffold/thermosensitive collagen hydrogel system, equipped with VEGF, to promote local osseointegration and angiogenesis. We also verified the VEGF release via thermosensitive collagen and proliferation and induction of the human umbilical vein endothelial cells (HUVECs) via the composite system in vitro. In vivo, using microscopic computed tomography (Micro-CT), histology, and immunohistochemistry analysis, we confirmed that the composite scaffold aids in angiogenesis-mediated bone regeneration, and promotes significantly more bone integration. We also discovered that the composite scaffold has excellent biocompatibility, provides bioactive VEGF for angiogenesis and osteointegration, and provides an important theoretical basis for the restoration of local blood supply and strengthening of bone integration.
Vibrio alginolyticus Triggers Inflammatory Response in Mouse Peritoneal Macrophages via Activation of NLRP3 Inflammasome
Authors: Wang Jinxin , Ding Qun , Yang Qiankun , Fan Hui , Yu Guili , Liu Feixue , Bello Babatunde Kazeem , Zhang Xiao , Zhang Tianmeng , Dong Jingquan , Liu Gang , Zhao Panpan
Published: November 2021

Vibrio alginolyticus is a food-borne marine Vibrio that causes gastroenteritis, otitis media, otitis externa, and septicemia in humans. The pathogenic mechanisms of V. alginolyticus have previously been studied in aquaculture animals; however, the underlying mechanisms in mammals remain unknown. In this study, an in vitro model of mouse peritoneal macrophages infected with V. alginolyticus was established. qPCR results revealed that V. alginolyticus induced the transcription levels of various cytokines, including IL-1β, IL-12, IL-18, TNF-α, IL-17, IL-6, IFN-γ, and IL-10, and the secretion level of IL-1β is the most significant. Inhibition assays with Ac-YVAD-CHO (a caspase-1 inhibitor) and Z-VAD-FMK (a pan-caspase inhibitor) were conducted to determine whether caspase-1 or caspase-11 is involved in V. alginolyticus-triggered IL-1β secretion. Results showed that IL-1β secretion was partly inhibited by Ac-YVAD-CHO and absolutely blocked by Z-VAD-FMK. To explore the sensed pattern recognition receptors, several NLR family members and the AIM2 receptor were detected and many receptors were upregulated especially NLRP3. Moreover, the NLRP3 protein displayed a puncta-like surrounding cell nucleus, which signified that the NLRP3 inflammasome was activated in response to V. alginolyticus infection. Inhibition assays with glyburide and CA-074 methyl ester (K+ outflow inhibitor and cathepsin B inhibitor) blocked IL-1β secretion, which demonstrated the essential role of the NLRP3 inflammasome in inflammatory response. To better understand how V. alginolyticus affects IL-1β release, the NLRP3 inflammasome was detected with doses ranging from 0.1 to 10 MOIs and time periods ranging from 3 to 12 h. Results showed that V. alginolyticus-mediated NLRP3 inflammasome activation was in a time- and dose-dependent manner and IL-1β release peaked at MOI of 1 for 12 h. Most importantly, blocking the NLRP3 inflammasome with inhibitors and the use of NLRP3-/- and caspase-1/11-/- mice could attenuate pro-inflammatory cytokine secretion, such as IL-1β, IL-6, IL-12, and TNF-α. Taken together, our study first found that the NLRP3 inflammasome plays vital roles in V. alginolyticus triggered inflammatory response in mouse peritoneal macrophages. This may provide reference information for the development of potential anti-inflammatory treatments against V. alginolyticus infection.
The Importance of Phonological Awareness in Learning Disabilities’ Prevention: Perspectives of Pre-School and Primary Teachers
Authors: Veríssimo Lurdes , Costa Marisa , Miranda Francisca , Pontes Catarina , Castro Isabel
Published: November 2021

There is robust empirical evidence regarding predictors of success in reading and writing. However, pre-school and primary teachers are not always aware of this evidence and often do not know how to apply it in practice. Considering the importance of the role of these teachers and the importance of early school years in preventing learning difficulties, it is essential to study teachers’ attitudes, knowledge, and strategies for improving educational processes toward successful development of literacy skills. Particularly, recognizing the impact of phonological awareness on the development of reading skills, this study has two main research questions: What is the importance pre-school and primary teachers attribute to the promotion of phonological awareness? and Which strategies for promoting phonological awareness do they apply in their professional practice? This qualitative study includes individual interviews with 10 pre-school and primary teachers, seeking to understand the perspective of each participant about phonological awareness, its importance, and implementation in practice. Data were collected in a context of great adversity (e.g., child maltreatment, early life stress). The results reveal that both pre-school and primary teachers recognized the relevance of phonological awareness among other pre-academic skills. Regarding the activities teachers implement, in their perspective, the playfulness seems to better result to stimulate this specific skill. Preschool teachers tend to focus on the dynamics that promote syllabic, intrasyllabic and phonemic awareness. Despite recognizing the gaps in phonological awareness in the first graders, primary teachers seem not to prioritize activities that stimulate and consolidate this skill, privileging the fluency and comprehension processes. The collaborative work between professionals was highlighted as very important to optimize the stimulation phonological awareness as well as facing other learning difficulties teachers find in this context. The results are discussed considering the role of pre-school teachers and primary teachers in reading difficulties’ prevention in contexts facing multiple vulnerabilities.
Metabolomics Analysis Discovers Estrogen Altering Cell Proliferation via the Pentose Phosphate Pathway in Infertility Patient Endometria
Authors: Zheng Yingxin , Zhu Yuemeng , Zhuge Ting , Li Bin , Gu Chao
Published: November 2021

Estrogen therapy is widely used as a supplementary treatment after hysteroscopy for female infertility patients owing to its protective function that improves endometrial regeneration and menstruation, inhibits recurrent adhesions, and improves subsequent conception rate. The endometrial protective function of such estrogen administration pre-surgery is still controversial. In the current study, 12 infertility patients were enrolled, who were treated with estrogen before hysteroscopy surgery. Using cutting-edge metabolomic analysis, we observed alterations in the pentose phosphate pathway (PPP) intermediates of the patient’s endometrial tissues. Furthermore, using Ishikawa endometrial cells, we validated our clinical discovery and identified estrogen–ESR–G6PD–PPP axial function, which promotes estrogen-induced cell proliferation.
LORSEN: Fast and Efficient eQTL Mapping With Low Rank Penalized Regression
Authors: Gao Cheng , Wei Hairong , Zhang Kui
Published: November 2021

Characterization of genetic variations that are associated with gene expression levels is essential to understand cellular mechanisms that underline human complex traits. Expression quantitative trait loci (eQTL) mapping attempts to identify genetic variants, such as single nucleotide polymorphisms (SNPs), that affect the expression of one or more genes. With the availability of a large volume of gene expression data, it is necessary and important to develop fast and efficient statistical and computational methods to perform eQTL mapping for such large scale data. In this paper, we proposed a new method, the low rank penalized regression method (LORSEN), for eQTL mapping. We evaluated and compared the performance of LORSEN with two existing methods for eQTL mapping using extensive simulations as well as real data from the HapMap3 project. Simulation studies showed that our method outperformed two commonly used methods for eQTL mapping, LORS and FastLORS, in many scenarios in terms of area under the curve (AUC). We illustrated the usefulness of our method by applying it to SNP variants data and gene expression levels on four chromosomes from the HapMap3 Project.