bluuebunny/crossref_metadata_2025 huggingface dataset:
Sublethal concentrations of conventional nematicides alter the physiological activities of Meloidogyne incognita and suppress parasitism
Authors: Abdel-Rahman Abdullah A. , Kesba Hosny H. , Mohamed Hoda G. , Kamel Donia F. , Ahmed Fatma S.
Published: January 2023

Reducing nematicide dose rates could be a useful strategy for mitigating their negative effects on health and the environment. In this study, enzymatic activities and the parasitic ability of Meloidogyne incognita after exposure to sub-lethal concentrations (0.25, 1, 2, and 5 ppm) of ethoprophos, fenamiphos, and oxamyl were investigated. Although the tested concentrations did not show nematicidal properties in vitro, they reduced root galls by at least 30% at 0.25 ppm and up to 67% at 5 ppm in pots, besides disrupting nematode fertility. For all three nematicides at 2 ppm, a chemotaxis assay showed that ≤ 11% of the nematode population was successfully oriented to the host roots, compared to 44% in the control. Ethoprophos and fenamiphos at 5 ppm showed poor inhibitory effects on acetylcholinesterase (AChE) activity (5.6% and 12.5%, respectively). In contrast, the same nematicides were shown to be strong ATPase inhibitors, causing 82.4% and 82.8% inhibition, respectively. At the same concentration, oxamyl moderately inhibited AChE and ATPase-specific activities, the inhibition being 22.5% and 35.2%, respectively. This study suggests that the use of very low nematicide concentrations could be a promising strategy for nematode management. Furthermore, it has also highlighted the role of ATPases as a possible target site for suppressing nematode activity in the development of future nematicides.
Energy valley optimizer: a novel metaheuristic algorithm for global and engineering optimization
Authors: Azizi Mahdi , Aickelin Uwe , A. Khorshidi Hadi , Baghalzadeh Shishehgarkhaneh Milad
Published: January 2023

In this paper, Energy Valley Optimizer (EVO) is proposed as a novel metaheuristic algorithm inspired by advanced physics principles regarding stability and different modes of particle decay. Twenty unconstrained mathematical test functions are utilized in different dimensions to evaluate the proposed algorithm's performance. For statistical purposes, 100 independent optimization runs are conducted to determine the statistical measurements, including the mean, standard deviation, and the required number of objective function evaluations, by considering a predefined stopping criterion. Some well-known statistical analyses are also used for comparative purposes, including the Kolmogorov–Smirnov, Wilcoxon, and Kruskal–Wallis analysis. Besides, the latest Competitions on Evolutionary Computation (CEC), regarding real-world optimization, are also considered for comparing the results of the EVO to the most successful state-of-the-art algorithms. The results demonstrate that the proposed algorithm can provide competitive and outstanding results in dealing with complex benchmarks and real-world problems.
Evaluation of the role of kefir in management of non-alcoholic steatohepatitis rat model via modulation of NASH linked mRNA-miRNA panel
Authors: Salah Noha , Eissa Sanaa , Mansour Amal , El Magd Nagwa M. Abo , Hasanin Amany Helmy , El Mahdy Manal M. , Hassan Mohamed Kamel , Matboli Marwa
Published: January 2023

Non-alcoholic steatohepatitis (NASH) is the clinically aggressive variant of non-alcoholic fatty liver disease. Hippo pathway dysregulation can contribute to NASH development and progression. The use of probiotics is effective in NASH management. Our aim is to investigate the efficacy of kefir Milk in NASH management via modulation of hepatic mRNA-miRNA based panel linked to NAFLD/NASH Hippo signaling and gut microbita regulated genes which was identified using bioinformatics tools. Firstly, we analyzed mRNAs (SOX11, SMAD4 and AMOTL2), and their epigenetic regulator (miR-6807) followed by validation of target effector proteins (TGFB1, IL6 and HepPar1). Molecular, biochemical, and histopathological, analyses were used to evaluate the effects of kefir on high sucrose high fat (HSHF) diet -induced NASH in rats. We found that administration of Kefir proved to prevent steatosis and development of the inflammatory component of NASH. Moreover, Kefir improved liver function and lipid panel. At the molecular level, kefir down-regulated the expression of miR 6807-5p with subsequent increase in the expression of SOX 11, AMOTL2 associated with downregulated SMAD4, resulting in reduction in the expression of the inflammatory and fibrotic markers, IL6 and TGF-β1 in the treated and prophylactic groups compared to the untreated rats. In conclusion, Kefir suppressed NASH progression and improved both fibrosis and hepatic inflammation. The produced effect was correlated with modulation of SOX11, SMAD4 and AMOTL2 mRNAs) – (miR-6807-5p) – (TGFB, IL6 and, HepPar1) expression.
Climate change multi-model projections in CMIP6 scenarios in Central Hokkaido, Japan
Authors: Peng Shilei , Wang Chunying , Li Zhan , Mihara Kunihito , Kuramochi Kanta , Toma Yo , Hatano Ryusuke
Published: January 2023

Simulation of future climate changes, especially temperature and rainfall, is critical for water resource management, disaster mitigation, and agricultural development. Based on the category-wise indicator method, two preferred Global Climate Models (GCMs) for the Ishikari River basin (IRB), the socio-economic center of Hokkaido, Japan, were examined from the newly released Coupled Model Intercomparison Project Phase 6 (CMIP6). Climatic variables (maximum/minimum temperature and precipitation) were projected by the Statistical DownScaling Model (SDSM) under all shared socioeconomic pathway-representative concentration pathway (SSP-RCP) scenarios (SSP1-1.9, SSP1-2.6, SSP2-4.5, SSP3-7.0, SSP4-3.4, SSP4-6.0, SSP5-3.4OS, and SSP5-8.5) in two phases: 2040–2069 (2040s) and 2070–2099 (2070s), with the period of 1985–2014 as the baseline. Predictors of SDSM were derived from CMIP6 GCMs and the reanalysis dataset NOAA-CIRES-DOE 20th Century Reanalysis V3 (20CRv3). Results showed that CMIP6 GCMs had a significant correlation with temperature measurements, but could not represent precipitation features in the IRB. The constructed SDSM could capture the characteristics of temperature and precipitation during the calibration (1985–1999) and validation (2000–2014) phases, respectively. The selected GCMs (MIROC6 and MRI-ESM-2.0) generated higher temperature and less rainfall in the forthcoming phases. The SSP-RCP scenarios had an apparent influence on temperature and precipitation. High-emission scenarios (i.e., SSP5-8.5) would project a higher temperature and lower rainfall than the low-emission scenarios (e.g., SSP1-1.9). Spatial–temporal analysis indicated that the northern part of the IRB is more likely to become warmer with heavier precipitation than the southern part in the future. Higher temperature and lower rainfall were projected throughout the late twenty-first century (2070s) than the mid-century (2040s) in the IRB. The findings of this study could be further used to predict the hydrological cycle and assess the ecosystem's sustainability.
Development, preparation, and evaluation of a novel dotted lateral flow immunochromatographic kit for rapid diagnosis of dermatophytosis
Authors: Aboul-Ella Hassan , Sayed Rafik Hamed , Abo-Elyazeed Heidy Shawky
Published: January 2023

Dermatophytosis is a widely spread contagious zoonotic disease, affecting both man (tinea) and animals (ringworm). This disease is caused by a group of closely related keratinophilic fungi known collectively as the dermatophytes group. Although the wide distribution of dermatophytosis cases throughout the whole world and its adverse clinical effect on human health, economical effect on productive animals, and pet animal welfare, there is no rapid accurate diagnostic tool for such disease. The current conducted study tries to accomplish the difficult equation by achieving an accurate, sensitive, specific, user-friendly, rapid, robust, device-less, deliverable to end-users, and economic cost for the development and production of diagnostic kits. Through the development of a rapid diagnostic kit based on immunochromatographic assay with three major affordable reproducible production stages; preliminary stage, developmental and standardization stage, and evaluation stage. Obtaining dermatophytes-specific polyclonal antibodies against criteria-based selected dermatophytes strains associating proper gold nanoparticle preparation, characterization, and conjugation, with proper loading of the different bio-reactants on the efficiently laminated and fabricated lateral flow strips were the main challenge and control points through the whole process. Also, as a result of examining 100 animal samples using the new kit, the κ coefficients of the kit with the direct microscopy while the kit with the culture were 0.44 and 0.76, respectively. Therefore, the newly designated and developed kit showed a very promising competitive diagnostic result within 5–7 min through easy-to-be-performed three steps.
Head CT deep learning model is highly accurate for early infarct estimation
Authors: Gauriau Romane , Bizzo Bernardo C. , Comeau Donnella S. , Hillis James M. , Bridge Christopher P. , Chin John K. , Pawar Jayashri , Pourvaziri Ali , Sesic Ivana , Sharaf Elshaimaa , Cao Jinjin , Noro Flavia T. C. , Wiggins Walter F. , Caton M. Travis , Kitamura Felipe , Dreyer Keith J. , Kalafut John F. , Andriole Katherine P. , Pomerantz Stuart R. , Gonzalez Ramon G. , Lev Michael H.
Published: January 2023

Non-contrast head CT (NCCT) is extremely insensitive for early (< 3–6 h) acute infarct identification. We developed a deep learning model that detects and delineates suspected early acute infarcts on NCCT, using diffusion MRI as ground truth (3566 NCCT/MRI training patient pairs). The model substantially outperformed 3 expert neuroradiologists on a test set of 150 CT scans of patients who were potential candidates for thrombectomy (60 stroke-negative, 90 stroke-positive middle cerebral artery territory only infarcts), with sensitivity 96% (specificity 72%) for the model versus 61–66% (specificity 90–92%) for the experts; model infarct volume estimates also strongly correlated with those of diffusion MRI (r2 > 0.98). When this 150 CT test set was expanded to include a total of 364 CT scans with a more heterogeneous distribution of infarct locations (94 stroke-negative, 270 stroke-positive mixed territory infarcts), model sensitivity was 97%, specificity 99%, for detection of infarcts larger than the 70 mL volume threshold used for patient selection in several major randomized controlled trials of thrombectomy treatment.
Os(ii/iii) complex supports pH-insensitive electrochemical DNA-based sensing with superior operational stability than the benchmark methylene blue reporter
Authors: Aller Pellitero Miguel , Kundu Nandini , Sczepanski Jonathan , Arroyo-Currás Netzahualcóyotl
Published: January 2023

This study reports an osmium-based redox reporter that enables pH-insensitive and fast DNA-based molecular sensing, offering new possibilities for the study of short-lived dynamic molecular events.
Engineering goat milk-derived extracellular vesicles for multiple bioimaging-guided and photothermal-enhanced therapy of colon cancer
Authors: Jing Boping , Gao Yu , Guo Feng , Jiang Dawei , Guo Rong , Wang Jing , Li Yuman , Xie Yuji , Chen Yihan , Li He , Zhang Li , Xie Mingxing , An Rui
Published: January 2023

Synthesis, application, and analysis of a GMV-based nanoprobe.
Versatile nanodiamond-based tools for therapeutics and bioimaging
Authors: Leung Hoi Man , Chu Hoi Ching , Mao Zheng-Wei , Lo Pik Kwan
Published: January 2023

In this feature article, properties of nanodiamonds in photophysics, surface modification and biocompatibility are discussed, followed by their applications in therapy and bioimaging.
CO2 hydrogenation to formic acid on Pd–Cu nanoclusters: a DFT study
Authors: Chattaraj D. , Majumder C.
Published: January 2023

Carbon dioxide (CO2) hydrogenation to formic acid is a promising method for the conversion of CO2 to useful organic products.
Structural evolution after oxidative pretreatment and CO oxidation of Au nanoclusters with different ligand shell composition: a view on the Au core
Authors: Truttmann Vera , Schrenk Florian , Marini Carlo , Palma Mireia , Sanchez-Sanchez Maricruz , Rameshan Christoph , Agostini Giovanni , Barrabés Noelia
Published: January 2023

The structural dynamics of supported monolayer protected Au nanoclusters after pretreatment and catalytic CO oxidation have been probed by XAS and XPS.
Insight at the atomic scale of corrosion inhibition: DFT study of 8-hydroxyquinoline on oxidized aluminum surfaces
Authors: Chiter Fatah , Costa Dominique , Pébère Nadine , Marcus Philippe , Lacaze-Dufaure Corinne
Published: January 2023

8-Hydroxyquinoline (8-HQ) is a promising organic molecule for the corrosion protection of aluminum and its alloys.
The surface charge induced high activity of oxygen reduction reaction on the PdTe2 bilayer
Authors: Huang Xiang , Wang Jiong , Zhao Changming , Gan Li-Yong , Xu Hu
Published: January 2023

Dissociation barrier of O2* plotted as a function of the surface charge on the PdTe2 bilayer.
Near-source hypochlorous acid emissions from indoor bleach cleaning
Authors: Stubbs Annastacia D. , Lao Melodie , Wang Chen , Abbatt Jonathan P. D. , Hoffnagle John , VandenBoer Trevor C. , Kahan Tara F.
Published: January 2023

Cleaning surfaces with sodium hypochlorite (NaOCl) bleach can lead to high levels of gaseous chlorine (Cl2) and hypochlorous acid (HOCl); these have high oxidative capacities and are linked to respiratory issues.
Polymeric and inorganic sorbents as a green option to recover critical raw materials at trace levels from sea saltwork bitterns
Authors: Vallès V. , López J. , Fernández de Labastida M. , Gibert O. , Leskinen A. , Koivula R. T. , Cortina J. L.
Published: January 2023

Saltwork brines could become a sustainable unknown source of strategic raw materials if selective sorbents are used.
In situ encapsulating cobalt phosphide into a quasi-MOF: a high-performance catalyst for hydrolytic dehydrogenation of ammonia borane
Authors: Yang Shiyu , He Ping , Tian Yao , Luo Yang , Jiang Jing
Published: January 2023

The development of efficient, durable and economical catalysts based on non-precious metals for the controllable and fast hydrogen evolution from chemical hydrogen storage materials is highly desirable for the hydrogen economy.
A cascade nanozyme with antimicrobial effects against nontypeable Haemophilus influenzae
Authors: Ma Xiaojing , Lang Jiayan , Chen Pengyu , Tang Wenjing , Shindler Simon , Yang Rong
Published: January 2023

A cascade nanozyme with glucose oxidase and haloperoxidase activities was designed and synthesized, which was shown to generate antiseptic HOBr from a ubiquitous non-ROS, O2. It successfully inhibited growth of a bacterial pathogen and its biofilm.
Rapid detection of cancer DNA in human blood using cysteamine-capped AuNPs and a machine learning-enabled smartphone
Authors: Koowattanasuchat Sireemas , Ngernpimai Sawinee , Matulakul Piyaporn , Thonghlueng Janpen , Phanchai Witthawat , Chompoosor Apiwat , Panitanarak Uthumporn , Wanna Yupaporn , Intharah Thanapong , Chootawiriyasakul Kanokon , Anata Pimjai , Chaimnee Prajuab , Thanan Raynoo , Sakonsinsiri Chadamas , Puangmali Theerapong
Published: January 2023

The methylation landscape (Methylscape) of normal and malignant DNAs is different, resulting in unique self-assembly patterns in solution. The dispersion of cysteamine-capped AuNPs adsorbed onto DNA clusters could be employed to identify cancer DNA.
Modification of plasmonic properties in several transition metal-doped graphene studied by the first principles method
Authors: Dzujah Diyan Unmu , Pradipto Abdul-Muizz , Hidayat Rahmat , Nakamura Kohji
Published: January 2023

Doping graphene with a single transition metal atom results in bandgap opening and partial filling of the mid-gap states, leading to the possibility of plasmon excitation with plasmon frequency depending on the TM dopant.
Enzymatic hydrolysis of low temperature alkali pretreated wheat straw using immobilized β-xylanase nanoparticles
Authors: Hamid Attia , Zafar Asma , Latif Sabahat , Peng Liangcai , Wang Yanting , Liaqat Iram , Afzal Muhammad Sohail , ul-Haq Ikram , Aftab Muhammad Nauman
Published: January 2023

A low temperature alkali (LTA) pretreatment method was used to treat wheat straw.
Cetrimonium bromide and potassium thiocyanate assisted post-vapor treatment approach to enhance power conversion efficiency and stability of FAPbI3 perovskite solar cells
Authors: Kumar Anjan , Singh Sangeeta , Sharma Dilip Kumar , Al-Bahrani Mohammed , Alhakeem Mohammed Ridha H. , Sharma Amit , Anil Kumar T. Ch.
Published: January 2023

Vapor treatment approach to enhance the power conversion efficiency and stability of FAPbI3 based perovskite solar cell.
Ultrafast black-color tunability of electrochromic dimming films using cobalt polyoxometalate-anchored nickel oxide nanoparticles
Authors: Jang Hwandong , Kim Jinbo , Han Minsu , Cho Cheolhyun , Kim Eunkyoung
Published: January 2023

A black color tunability of an electrochromic (EC) dimming device was explored using cobalt polyoxometalate (CoPW)-anchored nickel oxide nanoparticles (CoPW@NiOx).
Simple and efficient synthesis methods for fabricating anode materials of sodium-ion batteries and their sodium-ion storage mechanism study
Authors: Zhang Pan , Shu Yirui , Wang Ye , Ye Jinghua , Yang Lin
Published: January 2023

Waste plastic with rich ester bonds, polyterephthalate (PET), is selected as the precursor to synthesize HC with different micromorphologies via low-temperature pyrolysis strategies. The relationship between the microstructure and sodium-ion storage behavior is evaluated.
Inhibition of the P3–O3 phase transition via local symmetry tuning in P3-type layered cathodes for ultra-stable sodium storage
Authors: Zhou Ya-Nan , Xiao Zichun , Han Duzhao , Wang Suning , Chen Jinniu , Tang Wei , Yang Mingyu , Shao Le , Shu Chengyong , Hua Weibo , Zhou Dezhong , Wu Yuping
Published: January 2023

We reconfigure the sodiation/desodiation process of P3-type layered cathodes by a local symmetry tuning strategy to enhance their stability. The cathodes exhibit long-term cycling stability with a higher capacity retention of 74% after 2000 cycles at 1C.
Bandgap narrowing and piezochromism of doped two-dimensional hybrid perovskite nanocrystals under pressure
Authors: Shi Yue , Jin Zongqing , Lv Pengfei , Wang Kai , Xiao Guanjun , Zou Bo
Published: January 2023

We provide a facile pressure engineering to achieve the optical control of Mn doped 2D perovskite (PEA)2PbBr4 NCs. A successive bandgap narrowing and marked piezochromism which changes emission from orange to bluish violet were realized.
Biological tuners to reshape the bile acid pool for therapeutic purposes in non-alcoholic fatty liver disease
Authors: Gillard Justine , Leclercq Isabelle A.
Published: January 2023

Bile acids synthesized within the hepatocytes are transformed by gut microorganisms and reabsorbed into the portal circulation. During their enterohepatic cycling, bile acids act as signaling molecules by interacting with receptors to regulate pathways involved in many physiological processes. The bile acid pool, composed of a variety of bile acid species, has been shown to be altered in diseases, hence contributing to disease pathogenesis. Thus, understanding the changes in bile acid pool size and composition in pathological processes will help to elaborate effective pharmacological treatments.

Five crucial steps along the enterohepatic cycle shape the bile acid pool size and composition, offering five possible targets for therapeutic intervention. In this review, we provide an insight on the strategies to modulate the bile acid pool, and then we discuss the potential benefits in non-alcoholic fatty liver disease.
Developmental Language Disorder Is Associated With Slower Processing Across Domains: A Meta-Analysis of Time-Based Tasks
Authors: Zapparrata Nicole M. , Brooks Patricia J. , Ober Teresa
Published: January 2023

Purpose:

Individuals with developmental language disorder (DLD) often exhibit slower processing on time-based tasks in comparison with age-matched peers. Processing speed has been linked to various linguistic skills and might serve as a global indicator of individual differences in language abilities. Despite an extensive literature on processing speed in DLD, it remains unclear whether slower processing is domain general or restricted to linguistic and/or auditory tasks.

Method:

This meta-analysis used robust variance estimation to compare response/reaction times (RTs) of DLD and age-matched groups (
N
= 812 DLD, 870 neurotypical;
M
age
[DLD] = 8.9 years, range: 4.3–22.7 years). Moderators included task (simple RT, choice RT, naming, congruent/baseline conditions of interference control tasks), stimulus type (linguistic/nonlinguistic), stimulus modality (auditory/nonauditory), and response modality (verbal/nonverbal). Age and publication year were covariates.

Results:

The overall effect based on 46 studies and 144 estimates indicated longer mean RTs in DLD groups (
g
= .47,
p
< .001, 95% CI [.38, .55]). Moderator analyses indicated larger effects when tasks required verbal as opposed to nonverbal responses. No other moderators approached significance. All subgroup analyses were significant, indicating longer mean RTs in DLD groups across tasks, stimulus types, stimulus modalities, and response modalities.

Conclusions:

Individuals with DLD exhibit longer RTs across verbal and nonverbal tasks, which may contribute to observed difficulties in language, motor skills, and executive functioning. Simple processing speed measures should be included in screening for language delays but may not be suitable for differential diagnosis, given that slower processing may occur across multiple disorders.

Supplemental Material:

https://doi.org/10.23641/asha.21809355
Generalized linear‐constrained optimal power flow for distribution networks
Authors: Li Biao , Wan Can , Li Yunyi , Jiang Yibao , Yu Peng
Published: January 2023

Optimal power flow (OPF) plays an important role in the secure and economical operation of the distribution network. This paper proposes a novel generalized linear‐constrained optimal power flow (GLOPF) model for both radial and mesh distribution networks, which iteratively approaches the optimal solution to the original OPF problem. The first‐order Taylor series approximation method is applied to linearize the non‐linear and non‐convex power flow constraints for a given Taylor expansion point (TEP). In addition, the objective function of the GLOPF model is only added with an easy‐compute second‐order penalty on state variables, which is at least positive semi‐definite and guarantees the convexity of the quadratic optimization. Then a TEP‐based iterative (TEP‐I) method is proposed in the GLOPF model to construct a series of linear‐constrained convex quadratic optimizations, which avoids the complex calculation of quasi‐Hessian or Hessian matrices in traditional sequential programming methods. The converged solution to the GLOPF model is proved to satisfy the Karush–Kuhn–Tucker conditions of the original OPF problem. Furthermore, the GLOPF model at first and second iterations can be implemented as the ‘cold‐start’ and ‘warm‐start’ LOPF models, respectively. Case studies verify the super‐linear convergence and high accuracy of the proposed GLOPF model.
The Sun at millimeter wavelengths
Authors: Guevara Gómez Juan Camilo , Jafarzadeh Shahin , Wedemeyer Sven , Grant Samuel D. T. , Eklund Henrik , Szydlarski Mikołaj
Published: January 2023

Aims. We used solar observations of a plage-enhanced network with the Atacama Large Millimeter/sub-millimeter Array (ALMA) in Band 3 and Band 6, together with synthetic continuum maps from numerical simulations with Bifrost in the same bands, to carry out a detailed study of bright small-scale magnetic features.

Methods. We made use of an algorithm to automatically identify and trace bright features within the field of view (FoV) of the ALMA observations and the simulation. In particular, the algorithm recovers information of the time evolution of the shape, motion of the centre of gravity, temperature, and size for each feature. These quantities are used to determine the oscillatory properties of each feature utilising wavelets analysis.

Results. We found 193 and 293 features in the Bands 3 and 6 observations, respectively. In the degraded simulation, the total number of features were 24 for Band 3 and 204 for Band 6. In the original simulation, the total number of features were 36 for Band 3 and 392 for Band 6. Based on the simulation, we confirm the magnetic nature of the features. We have obtained average oscillation periods of 30–99 s for the temperature, 37–92 s for size, and 37–78 s for horizontal velocity. There are indications for the possible presence of transverse (kink) waves with average amplitude velocities of 2.1–5.0 km s−1. We find a predominant anti-phase behaviour between temperature and size oscillations suggesting that the variations of the bright features are caused by compressible fast-sausage magnetohydrodynamics (MHD) modes. For the first time to our knowledge, we estimated the flux of energy of the fast-sausage waves at the chromospheric heights sampled by ALMA as 453–1838 W m−2 for Band 3 and 3640–5485 W m−2 for Band 6.

Conclusions. We have identified MHD waves, both transverse (kink) and compressible sausage modes, in small-scale (magnetic) structures, independently, in both ALMA Band 3 and Band 6 observations, along with their corresponding synthetic images from simulations. The decrease of wave energy-flux with height (from Band 6 to Band 3) could possibly suggest energy dissipation at chromospheric heights, namely, wave heating, with the assumptions that the identified small-scale waves are typical at each band and they propagate upward through the chromosphere.
The CARMENES search for exoplanets around M dwarfs
Authors: Kossakowski D. , Kürster M. , Trifonov T. , Henning Th. , Kemmer J. , Caballero J. A. , Burn R. , Sabotta S. , Crouse J. S. , Fauchez T. J. , Nagel E. , Kaminski A. , Herrero E. , Rodríguez E. , González-Álvarez E. , Quirrenbach A. , Amado P. J. , Ribas I. , Reiners A. , Aceituno J. , Béjar V. J. S. , Baroch D. , Bastelberger S. T. , Chaturvedi P. , Cifuentes C. , Dreizler S. , Jeffers S. V. , Kopparapu R. , Lafarga M. , López-González M. J. , Martín-Ruiz S. , Montes D. , Morales J. C. , Pallé E. , Pavlov A. , Pedraz S. , Perdelwitz V. , Pérez-Torres M. , Perger M. , Reffert S. , Rodríguez López C. , Schlecker M. , Schöfer P. , Schweitzer A. , Shan Y. , Shields A. , Stock S. , Wolf E. , Zapatero Osorio M. R. , Zechmeister M.
Published: January 2023

We present the discovery of an Earth-mass planet (Mb sin i = 1.26 ± 0.21 M⊕) on a 15.6 d orbit of a relatively nearby (d ~ 9.6 pc) and low-mass (0.167 ± 0.011 M⊙) M5.0 V star, Wolf 1069. Sitting at a separation of 0.0672 ± 0.0014 au away from the host star puts Wolf 1069 b in the habitable zone (HZ), receiving an incident flux of S = 0.652 ± 0.029 S⊕. The planetary signal was detected using telluric-corrected radial-velocity (RV) data from the CARMENES spectrograph, amounting to a total of 262 spectroscopic observations covering almost four years. There are additional long-period signals in the RVs, one of which we attribute to the stellar rotation period. This is possible thanks to our photometric analysis including new, well-sampled monitoring campaigns undergone with the OSN and TJO facilities that supplement archival photometry (i.e., from MEarth and SuperWASP), and this yielded an updated rotational period range of Prot = 150–170 d, with a likely value at 169.3−3.6+3.7. The stellar activity indicators provided by the CARMENES spectra likewise demonstrate evidence for the slow rotation period, though not as accurately due to possible factors such as signal aliasing or spot evolution. Our detectability limits indicate that additional planets more massive than one Earth mass with orbital periods of less than 10 days can be ruled out, suggesting that perhaps Wolf 1069 b had a violent formation history. This planet is also the sixth closest Earth-mass planet situated in the conservative HZ, after Proxima Centauri b, GJ 1061 d, Teegarden’s Star c, and GJ 1002 b and c. Despite not transiting, Wolf 1069 b is nonetheless a very promising target for future three-dimensional climate models to investigate various habitability cases as well as for sub-m s−1 RV campaigns to search for potential inner sub-Earth-mass planets in order to test planet formation theories.
Research on the Reform and Innovation of Financial Management in Higher Universities under the Double-Class Construction Background: A Case from China University of Geosciences (Beijing)
Authors: He Yufeng , Wang Jie , Zhang Hui , Wang Yinhong
Published: January 2023

Under the double-class construction background, the financial management has gradually become one of the most important contents of higher universities. It is the basement of all economic activities in colleges and universities, determines the basic direction of financial management, and is also subject to the overall development goal of colleges and universities. With the transition of the economic system of colleges and universities, the reform of the financial system and the continuous change of the financial management environment, the financial management is facing the challenge of informatization, knowledge and networking, which require colleges and universities to reform the original financial management system and innovate the concept, content and mode of financial management to adapt to the changes of colleges and universities in the new stage. Taking China University of Geosciences (Beijing) as an example, this paper analyses the necessity of financial management reform and innovation, and puts forward several suggestions for reform and innovation of financial management, so as to continuously improve the financial management level of higher universities under the double-class construction background.
Establish Discipline and Specialty Laboratories and Explore the Training of Applied Talents in Local Comprehensive Universities
Authors: Deng Bolin
Published: January 2023

Experimental teaching is an important part of the teaching system of universities, and the laboratory is an important platform for experimental teaching and scientific research. The level of experimental teaching and laboratory construction in universities is an important symbol of cultivating applied talents and reflecting the comprehensive strength of universities. Tea major is a characteristic specialty of Pu'er University. With the characteristics of Pu'er tea technology and cultural research, the discipline has shown a good momentum of development in local universities in Yunnan Province; in this paper, we take the establishment of tea science laboratory in Pu'er University as an example to explore the key issues of the cultivation of applied talents in local comprehensive universities. Finally, we summarize the practical experience of Pu'er University in this regard, which provides a demonstration for the experimental teaching reform and the cultivation of applied talents in local comprehensive universities.
Research on Teaching Reform of Artificial Intelligence Course Based on CDIO
Authors: Guan Xu , Yan Hailong , Wang Zirui , Gao Peng , Ding Baozhu
Published: January 2023

In view of the problem of how to set up general undergraduate artificial intelligence courses, on the basis of carefully combing and summarizing years of teaching exploration and practice, it is proposed to set Artificial Intelligence (AI) courses in the lower grades of the university. Taking the teaching practice carried out by Liaoning Institute of Science and Engineering as an example, the “12365” principle is proposed based on the CDIO concept, and corresponding teaching reform and practice are carried out.
Offline First-class Graduate Course Construction Practice: Taking the Modern Agricultural Innovation and Rural Revitalization Strategy Course as an Example
Authors: Bao Wen , Liu Qian , Zhou Yanqing
Published: January 2023

In the process of offline first-class graduate course construction, teachers should update the teaching idea, explore the curriculum reform, strengthen the classroom teaching, innovative teaching mode, promote teaching, with student development as the centre, is committed to tap students 'inner potential and stimulate learning motivation, pay attention to students' morality, intellectual and physique all-round development, ensure the teaching quality. In order to cultivate students' professional ability and innovation ability, the article first of the modern agricultural innovation and rural revitalization of strategic course construction content introduction, and then expounds the modern agricultural innovation and rural revitalization of strategic course construction ideas, finally discusses the modern agricultural innovation and rural revitalization strategy course as offline first-class graduate course construction practice.
Build A Multi-Dimensional Collaborative Logistics Talent Training Model -Taking Chengdu University of Information Technology as an example
Authors: Liu Chenghua , Yang Chunxia
Published: January 2023

The “Opinions of the Ministry of Education on Accelerating the Construction of High-level Undergraduate Education to Comprehensively Improve the Ability of Talent Training (Jiao Gao [2018] No. 2)” clearly requires that the formation of a high-level undergraduate talent training system should be accelerated around the overall improvement of talent training capabilities. After 18 years of development, the logistics major of our school has made certain achievements in professional construction, teacher team construction, teacher teaching ability construction and experimental teaching guarantee construction, forming a relatively complete talent training system, but the social adaptation of talent training Sex still needs to be improved. This paper adheres to the problem orientation, based on the concept of collaborative education, and builds a multi-dimensional collaborative education talent training model from multiple perspectives, such as promoting the integration of production and education, condensing professional characteristics, implementing segmented training and building a capacity improvement system, and comprehensively improving the ability of logistics personnel training.
Industrial Development Layout and Competitiveness Evaluation Based on Correlation Analysis between Power and Industry
Authors: Zhang Xifeng , Xue Meimei , Lv Pan , Wang Huachun , Li Zhipeng , Zhou Jinshuang , Li Suxiu
Published: January 2023

The change of industrial structure has a significant impact on energy consumption. The coordinated development between energy structure and industrial structure has a profound impact on the steady development of national economy and society. In this paper, focusing on the needs of industrial development layout and combining with the scenario of dual-carbon target constraint setting, a power-industry management analysis model is constructed, and a differentiated screening mechanism of industrial layout is realized under the three scenario Settings of dual-carbon target. According to the industrial development layout of Xinjiang, this paper studies the relationship between industrial development and energy and electricity consumption under different scenarios, selects the key industries according to the requirements of different scenarios, and carries out the scene comparison evaluation based on the industrial competitiveness evaluation. Finally, the paper puts forward specific suggestions from the perspectives of applying the coordinated layout of different scenes in stages, taking into account the coordination of regional layout, and striving for the practical linkage between industry and electric power.
AI Widens the Gap between the Rich and the Poor
Authors: Qiu Runqing , Liu Zhanhong
Published: January 2023

Since entering the 21st century, high technology has developed at a rapid pace. The development of high technology has changed the methods of production and lifestyle of human beings. While enjoying the efficiency, comfort, and convenience brought by high technologies, people find that the gap between the rich and the poor has been widening. More and more attentions have been paid to the influences on the gap between the rich and the poor arising from the development of high technologies, especially from the development of artificial intelligence (AI) technology. This paper focuses on this social phenomenon and demonstrates that the development of AI will widen the gap between the rich and the poor. The paper will proceed with the discussion from three levels of human actives: individual, company, and country.
Marginal Discrepancy of Five Contemporary Dental Ceramics for Anterior Restorations
Authors: Nawafleh Noor , Hatamleh Muhanad , Janzeer Yasmeen , Alrahlah Ali , Alahadal Khold
Published: January 2023

Objectives This study aimed to compare marginal accuracy of five contemporary all-ceramic crowns indicated for anterior restorations.

Materials and Methods A master die of maxillary central incisor was prepared for all-ceramic crown and duplicated to produce 50 replicas of epoxy resin material. Five ceramic materials were used to mill the crowns (n = 10). All crowns were manufactured following the same digital workflow; same master die, scanning unit and design software, and the recommended manufacturing protocol. Final seating of crown was secured by a small droplet of temporary cement on its incisal edge. Marginal accuracy was evaluated by scanning electronic microscope with a magnification of 300 × . Vertical marginal gap was measured for each crown at predefined four points.

Statistical Analysis One-way analysis of variance was used to test differences between groups and Tukey test was used for multiple comparisons between group combinations. A level of significance at 95% was set for all statistics.

Results The highest mean marginal gap and mean maximum gap calculated were for the e.max CAD crowns (49.2 µm, 87.6 µm), while the lowest values were for the Cercon xt crowns (10.2 µm, 21.7 µm). The mean marginal gap and the mean maximum gap of the e.max CAD crowns were statistically significantly greater than those of all other groups (p < 0.05). However, the differences between all other combinations were insignificant (p > 0.05).

Conclusion Marginal accuracy of lithium disilicate crowns is clinically acceptable. Zirconia and zirconia-reinforced lithium silicate materials can produce a greater level of marginal accuracy compared to lithium disilicate.
Effect of Lipopolysaccharide-Induced Apical Periodontitis in Diabetes Mellitus Rats on Periapical Inflammation
Authors: Prasetyo Eric Priyo , Sampoerno Galih , Juniarti Devi Eka , Cahyani Febriastuti , Saraswati Widya , Kuntjoro Mefina , Tjendronegoro Evelyn
Published: January 2023

Objectives To evaluate periapical inflammation through immunohistochemical analysis of interleukin 6 (IL-6) and tumor necrosis factor α (TNF-a) expression resulting from lipopolysaccharide (LPS)-induced apical periodontitis in diabetes mellitus rats, observed at 14, 28, and 42 days.

Materials and Methods Diabetes model on rats was induced by streptozotocin (STZ). Fifteen rats were injected with low-dose STZ for 5 days and waited for 5 days until the blood glucose level was stable and measured above 300 mg/dL confirmed by a digital glucometer. LPS was used to induce apical periodontitis. After performing access cavity, pulpal and root canal extirpation was done on the right mandibular first molar's root canal space of rats, under anesthesia. LPS of 1 mg/mL dose was induced in the pulpal and root canal space. Apical periodontitis was expected 14 days afterward and then, the rats were randomly allocated to three groups. The first group was terminated 14 days after induction and used as control. The second group was observed 28 days after induction, and the third group was observed 42 days after induction. IL-6 and TNF-a expression was analyzed by immunohistochemistry on macrophages in the periapical area.

Statistical Analysis Data were analyzed using one-way ANOVA and continued with the post hoc Tukey HSD test. Significance was considered if p < 0.05.

Results LPS induced apical periodontitis in diabetes mellitus rats at control (14 days), 28 and 42 days observation showed a significant increase in the expression of IL-6 and TNF-a. There were significant differences between the control and observed groups (p < 0.05). The expression of IL-6 in the apical area was not significant at 14 and 28 days (p > 0.05) but increased significantly at 42 days (p < 0.05). The expression of TNF-a in the apical area was significantly increased after 14 days (p < 0.05) and remained stable at 28 and 42 days (p > 0.05).

Conclusions The periapical inflammation of LPS-induced apical periodontitis in diabetes mellitus rats increased macrophages' expression of IL-6 at 42 days and TNF-a at 28 days.
Lipoma in Parotid Gland: A Rare Case Report
Authors: Santoso Sergio , Rizqiawan Andra , Mulyawan Indra , Wihandono Asdi , Amir Muhammad Subhan
Published: January 2023

Lipoma is a benign, rare, mesenchymal tumor found in the head and neck region, especially in the parotid gland. It thus requires a careful and precise examination to establish a diagnosis. A surgical procedure of the parotid gland is challenging due to the associated risk factor of facial nerve injury. We report a rare case of head and neck region lipoma between the superficial and deep lobe of the parotid gland. A 44-year-old female patient was presented with the chief complaint of a painless lump on the left front ear to the left cheek for about 1 year. There were no complaints of tooth pain before the lump appeared, and there were no lumps in other regions. A fine-needle aspiration biopsy, ultrasonography, and magnetic resonance imaging were all performed to establish the preoperative diagnosis and to plan the correct surgical approach. Lipoma was the initial clinical diagnosis, and a surgical excision with superficial parotidectomy and facialis nerve preservation was performed. Follow-up examinations were conducted to assess any facial nerve injury complications. Conclusion Lipoma rarely grows in the parotid gland. Careful diagnosis should be performed to establish a precise surgery for parotid dissection and facial nerve preservation.
The effect of implicit racial bias on right-wing populist support
Authors: Olsson Filip
Published: January 2023

This paper examines the link between implicit racial bias and right-wing populism. Using data from 41,803 participants, I explore whether implicit racial bias predicts the support of right-wing populist parties (RPP) in France, Belgium, and the Netherlands. The results reveal a significant association between implicit racial bias and support of RPP, even when controlling for explicit bias. Additional analyses show that the effect of implicit racial bias is especially high for participants with high levels of explicit racial bias. Participants with negative explicit racial bias are thus especially likely to support RPP if they also have high levels of negative implicit racial bias. The study also finds a significant effect for participants with no explicit racial bias, although the effect is markedly smaller.
Tripling energy storage density through order–disorder transition induced polar nanoregions in PbZrO3 thin films by ion implantation
Authors: Luo Yongjian , Wang Changan , Chen Chao , Gao Yuan , Sun Fei , Li Caiwen , Yin Xiaozhe , Luo Chunlai , Kentsch Ulrich , Cai Xiangbin , Bai Mei , Fan Zhen , Qin Minghui , Zeng Min , Dai Jiyan , Zhou Guofu , Lu Xubing , Lou Xiaojie , Zhou Shengqiang , Gao Xingsen , Chen Deyang , Liu Jun-Ming
Published: January 2023

Dielectric capacitors are widely used in pulsed power electronic devices due to their ultrahigh power densities and extremely fast charge/discharge speed. To achieve enhanced energy storage density, maximum polarization (Pmax) and breakdown strength (Eb) need to be improved simultaneously. However, these two key parameters are inversely correlated. In this study, order–disorder transition induced polar nanoregions have been achieved in PbZrO3 thin films by making use of the low-energy ion implantation, enabling us to overcome the trade-off between high polarizability and breakdown strength, which leads to the tripling of the energy storage density from 20.5 to 62.3 J/cm3 as well as the great enhancement of breakdown strength. This approach could be extended to other dielectric oxides to improve the energy storage performance, providing a new pathway for tailoring the oxide functionalities.
Heterogeneous pair-approximation analysis for susceptible–infectious–susceptible epidemics on networks
Authors: Wu Qingchu , Chen Shufang
Published: January 2023

The pair heterogeneous mean-field (PHMF) model has been used extensively in previous studies to investigate the dynamics of susceptible–infectious–susceptible epidemics on complex networks. However, the approximate treatment of the classical or reduced PHMF models lacks a rigorous theoretical analysis. By means of the standard and full PHMF models, we first derived the equivalent conditions for the approximate model treatment. Furthermore, we analytically derived a novel epidemic threshold for the PHMF model, and we demonstrated via numerical simulations that this threshold condition differs from all those reported in earlier studies. Our findings indicate that both the reduced and full PHMF models agree well with continuous-time stochastic simulations, especially when infection is spreading at considerably higher rates.
Asymptotic stability of the 2D MHD equations without magnetic diffusion
Authors: Dong Lihua , Ren Xiaoxia
Published: January 2023

We investigate the asymptotic stability of certain steady solution to the 2D MHD equations without magnetic diffusion in an infinite strip domain. Decay rates of smooth solution to that system are also given.
Review of performance enhancement of anaerobic digestion with the aid of biochar and future perspectives
Authors: Singhal Shailey , Agarwal Shilpi , Singhal Naveen
Published: January 2023

Anaerobic digestion (AD), one of the most promising routes for producing clean energy from biodegradable wastes, encounters difficulties at operational and mechanistic levels impacting its overall efficiency. Along with other solutions to overcome this problem, biochar has arrived as a worthwhile additive to enhance the performance of the process. This review aims to discuss various perspectives of biochar addition to an anaerobic digester. It summarizes the mechanism of biochar action during AD. A direct inter-species electron transfer offers a synergistic mechanism specifying different aspects of biogas production. The importance of characteristics of biochar (ion-exchange capacity, surface properties, electrical conductivity, and hydrophobicity) has been explained in enhancing AD performance. Studies indicate that a surface area >150 m2/g and a particle size <1 cm can be referred to as benchmark along with its supporting properties apt for AD. Researchers have recommended varying amounts of biochar (up to 15 g/l) for optimizing biogas production. The applicability of biochar for upgrading the biogas with respect to significant impurities (CO2, H2S, and NH3) has been discussed in detail. Along with the beneficial effects of biochar, its limitations in AD have also been identified, which need to be addressed wisely in order to optimize the process and make an unbiased shift toward validating the candidature of biochar in AD. The whole discussion indicates that consciously planned scheme utilizing biochar may be helpful in enhancing the effectiveness of AD for biogas generation, which may prove to be an impactful technology in the world of renewable energy.