bluuebunny/crossref_metadata_2025 huggingface dataset:
Mortalidad del coral Acropora palmata por una enfermedad similar al white pox en la bahía de Cinto, Parque Nacional Natural Tayrona, Caribe colombiano
Authors: Navas-Camacho Raúl , Franke Ante Rebeca , Acosta Chaparro Andrés
Published: December 2022

El Parque Nacional Natural Tayrona, ubicado en la costa Caribe colombiana, está formado por una costa de acantilados y bahías en su mitad occidental, en cuyo interior se encuentran formaciones coralinas. En 2005 se encontró una formación en la bahía de Cinto dominada por Acropora palmata afectada por una enfermedad cuyas lesiones eran similares a las causadas por la enfermedad de White Pox. Durante los siguientes dos años se realizó un seguimiento a 15 lesiones mediante registro fotográfico en tres ocasiones distintas (mayo y agosto de 2006 y marzo 2007), coincidiendo con las dos épocas climáticas contrastantes de la región. Se encontró un crecimiento permanente en todas las lesiones con un promedio de 0,8 cm2/día. Contrario a lo observado en el white pox y otras enfermedades en la región, estas lesiones no dejaron de crecer al descender la temperatura en los primeros meses del año. Este trabajo describe el aspectogeneral, los distintos estadios de crecimiento y la velocidad con que se expanden las lesiones en comparación con estudios previos en el Caribe. Por su aspecto y porque solo afectaba a colonias de A. palmata se pensó que se trataba de white pox, pero esta hipótesis no pudo verificarse concluyentemente.
PENTINGNYA CORPORATE SOCIAL RESPONBILITY DAN CORPORATE IMAGE UNTUK MEMBENTUK LOYALITAS NASABAH DI BMT MANDIRI SEJAHTERA CABANG KRANJI LAMONGAN
Authors: Roisul Abror M. Fakhri , Safitri Rini
Published: December 2022

Penelitian ini bertujuan untuk mengetahui pengaruh corporate social responsibility dan corporate image terhadap loyalitas nasabah. Penelitian ini dilakukan pada nasabah BMT Mandiri Sejahtera Cabang Kranji Lamongan. Populasi pada penelitian ini 2.207 nasabah dengan sampel 96 nasabah. Adapun metode dalam penentuan sampel menggunakan purposive sampling. Pengumpulan data dilakukan dengan menyebarkan kuesioner langsung kepada nasabah. Penelitian ini menggunakan jenis penelitian kuantitatif melalui pendekatan explanatory research. Adapun pengujian hipotesis menggunakan Statistical Product and Service Solution (SPSS). Adapun penelitian memperoleh hasil bahwa secara pasrial variabel corporate social responsibility mempunyai pengaruh yang positif serta signifikan dalam mendukung sikap loyal terhadap nasabah. Untuk variabel corporate image menunjukkan jika ada pengaruh positif dan juga signifikan yang dihasilkan pada loyalitas nasabah. Dalam pengujian simultan antara variabel corporate social responsibility dan corporate image juga memberi hasil yang sama yaitu terdapat pengaruh yang bersifat positif serta signifikan yang ada pada sikap loyal dari nasabah di BMT Mandiri Sejahtera Cabang Kranji Lamongan.
Development and validation of bio analytical liquid chromatography and mass spectrometry method for quantification of upadacitinib in human plasma
Authors: Srinivasarao Pakalapati , Chidananda Swamy Rumalla , Raghu Babu Korupolu , Muralidharan Kaliyaperumal
Published: December 2022

In the present investigation, a simple, rapid and sensitive liquid chromatography and mass spectrometry (LC/MS) method was developed for quantification of Upadacitinib (UCB) in spiked human plasma. The drug UCB was extracted by liquid –liquid extraction using diethyl ether and chloroform in the ratio of 75:25 (v/v). The drug Leflunomide (LFM) was used as an internal standard. The extracted drug mixture was followed by the liquid chromatography mass spectrometry (LC/MS) analysis and electrospray ionization interface. The chromatographic separation of UCB was carried out on Phenomenex Luna C18 column (100mm X 2.0 mm X 5μm) at ambient temperature followed by isocratic elution of 0.05% formic acid in methanol and acetonitrile in the ratio of 65:30(v/v). The method is concluded at a flow rate of 0.8 mL/min, 262 nm of UV detector wavelength. Protonated ions formed by electrospray ionization were recorded in the positive mode and were used to detect the analyte (UCB) with internal standard (LFM). The mass detection was made by monitoring the fragmentation of m/z 381.0 for UCB m/z 271.0 for LCM on mass spectrometer. The method was validated for accuracy, precision, linearity and recovery. The assay was linear over the entire range of calibration standards i.e 2.5-500ng/mL. The recoveries of the UCB after liquid-liquid extraction at 5, 20, 35 ng/mL were 100.7, 99.4 and 99.8. The lowest limit of the analytical method of UCB was 2 ng/mL in spiked human plasma. The developed method was successfully validated and can be used for determination of the pharmacokinetic parameters of the UCB in biological samples.
Metal-doped TiO2 photocatalyst as antibacterial - A Review
Authors: . Sufiati , Ayn Siti Nur , Sulistiyani Ika , Nurdin Muhammad , Salim La Ode Agus
Published: December 2022

Photocatalyst nanomaterials are developing as new materials for many applications. Titanium dioxide (TiO2) is a photocatalyst nanomaterial widely applied to solar cells, chemical sensors, health products and paint pigmentation. In this review article, we aim to provide a comprehensive overview of the development of the metal as a TiO2 doping material and its application as an antibacterial. TiO2 as an antimicrobial photocatalyst has been widely reported. Sol-gel synthesis method on semiconductors can make nanoparticle size, not agglomerate, homogeneous, pure and control mass distribution. Metal-doped TiO2 can activate the performance of TiO2 to work on visible light, thereby increasing the performance of TiO2 in its application as an antibacterial. Nickel (Ni), copper (Cu), manganese (Mn) and sulfur (S) have been shown to affect increasing the performance of TiO2 to inhibit bacteria in visible light. TiO2/Ni has antibacterial activity against Staphylococcus aureus (S. aureus) bacteria. TiO2/Cu has antibacterial activity against Escherichia coli (E.coli), S. aureus, Klebsiella pneumonia (K. Pneumonia) and Saccharomyces sp.. TiO2/Mn/S has antibacterial activity against Bacillus coagulans (B. Coagulans) and (K. Pneumonia). This review can add to the knowledge and the latest developments of metaldoped TiO2 photocatalysts based on antibacterial properties to be applied to water-purifying membranes, skin health and self-cleaning paints.
Combinatorial effect of chemotherapeutic drugs with natural products improves the combat against cancer cell drug resistance
Authors: Mirunalini S. , Manobharathi V. , Kalaiyarasi D.
Published: December 2022

Cancer is one of the world's leading causes of death making it an enticing condition to research and potentially develops prevention options. Separate or in combination,Surgery, Radiation, Targeted treatments and Immunotherapy are widely used to treat cancer. These treatment strategies are becoming highly futile and tend to have achieved a clinical deficit due to massive side effects and multidrug resistance. Therefore, anti-cancer specific chemotherapy was needed to address and potentially solve this dilemma. The drawback of chemotherapy is the development of drug resistance. Naturally derived compounds were the cornerstone of chemotherapy for the last 40 years. Recent progress has allowed researchers to fully explore the possible use of effective, well suitable, sideeffect- free natural bio-active compounds along with well-proven chemotherapeutic drugs for treating or regulating cancer. However, merely a few substances were trialled in several cancer patients and there is only marginal knowledge of their therapeutic efficacy. Hereby, in this review, we discuss the efficacy of existing chemotherapy drugs such as Cisplatin, Doxorubicin, Paclitaxel, Methotrexate, 5-Fluorouracil and some natural compounds (Curcumin, Capsaicin, 3,3′Diindolylmethane (DIM), Lupeol, Diosgenin and Ellagic acid) and their beneficial effects on cancer. This systematic review strongly admits the use of these compounds in patients with advanced and/or metastatic cancers, along with chemotherapy drugs.
The role of autophagy for cancer treatment: A systematic review
Authors: Poornimaa Murali , Ramanathan Karuppasamy
Published: December 2022

Autophagy is a highly conserved catabolic process that regulates nutrient deprivation and metabolic stress through lysosomal degradation. In addition, autophagy is also identified to regulate various processes such as maintaining cellular homeostasis, conserving genomic stability, immunity, inflammation and quality control. The dysregulation of autophagy promotes the development of various diseases such as obesity, diabetes, neurodegenerative disease and cancer. However, autophagy expresses a dichotomous role in cancer. During the initial stage of malignancy, autophagy acts as a suppressor. Nevertheless, in the established tumors, autophagy is exploited as an adaptive mechanism to support the growing energy needs induced by hypoxia and oxidative stress. Therefore, the prosurvival role of autophagy is prominent in advanced tumorigenesis. Despite its role in cancer, autophagy also significantly contributes to the cancer metastasis, maintenance of cancer stemness and anoikis resistance. Further, these findings speculate the need for inhibiting the prosurvival autophagy from augmenting treatment modalities. Recently, anti-autophagic therapies emerged as alternative approach for effective cancer treatment. Thus, in this review, we briefly discussed the dynamic function of autophagy in cancer and the key factors and pathways that mediate tumor-induced autophagy. Finally, we highlighted some of the target-specific antagonists that could harness against the prosurvival autophagy and could serve as effective cancer therapeutics in the future.
Effect of Nickel Substitution on Structural and Magnetic Properties of Novel Polyol route Synthesized Cobalt Ferrite
Authors: Birmule P.R. , Chavan A.S. , Jadhav B.V. , Burungale A.S. , Helavi-Reddy V.B. , Patil R.P.
Published: December 2022

Nanocrystalline NixCo1-xFe2O4 (1.0 ≥ x ≥ 0) ferrites were prepared by polyol route. Formation of single phase cubic spinel structure for all the compositions was confirmed from their X-ray diffraction patterns. These ferrite samples existed as crystalline nanoparticles of about 10-20 nm size as observed from Transmission Electron Microscopy technique. The magnetic studies indicated that, the ferrimagnetic behavior increases with nickel substitution.
Pharmacological significance of Oxadiazole scaffold
Authors: Santhanalakshmi K. , Margandan K. , Manivannan P. , Jacquline Rosy P.
Published: December 2022

Heterocycles come under an important branch of organic chemistry that contains at least one atom other than carbon as a part of ring system. The most common hetero atoms that are widely used are nitrogen, oxygen and sulphur. In synthetic organic chemistry, synthesis of heterocyclic compound is of immense interest due to its therapeutic applications and their existence in several natural products like vitamins, hormones, antibiotics and alkaloids. The oxadiazole nucleus is one of the most significant and well known heterocyclic compounds due to its broad range of pharmacological and therapeutic activities like anti-depressant, anticonvulsant, anti-proliferate, anti-fungal, antiinflammatory, anti-cancer, anti-HIV, insecticidal, antimiotic, herbicidal, hypoglycemic and muscle relaxant etc. The wide and potent activities of oxadiazole and their derivatives have established them as pharmacologically significant scaffolds. The basic heterocyclic rings present in the several medicinal agents are 1,2,3-oxadiazole, 1,2,4- oxadiazole, 1,2,5- oxadiazole and 1, 3, 4- oxadiazole. Research has focused on oxadiazole and their derivatives to prove the pharmacological importance of heterocyclic nucleus. The present review will summarize the pharmacological activities reported for oxadiazole derivatives.
Racemic Guaifenesin Preparation by in vivo Williamson ether synthesis and FTIR, NMR, HPLC and GCMS spectral analysis
Authors: Kumarasamy Suresh , Vasuki Selvaraj , Narayanan Mathiyazhagan , Ranganathan Muthusamy
Published: December 2022

The preparation of racemic guaifenesin (3-(2- methoxyphenoxy)-1,2-propanediol by a Williamson ether synthesis reaction was well-suited towards the reaction mechanisms, spectroscopic analysis and pharmaceutical synthesis of enantioselective compound. Analysis of the reaction products includes NMR, HPLC, GC techniques that involve comparison of the reaction products to known standards. The most characteristic peaks in an IR spectrum are those associated with O-H bonds (strong, broad peaks, 2968.80 cm--1) and the carbonyl group (C=O, strong peaks 1379.10 cm--1). Identification of synthesized product structure chemical shift occurred at 3.2 ppm indicating the presence of methyl compound in structure of guaifenesin and the molecular mass synthesized product was found to be 198g/mol for guaifenesin compound with the CAS No.of 93-14-1.
Chemical characterization and source apportionment of ambient PM10 in Hubli-Dharwad region, Karnataka, India
Authors: Navalgund Lokeshwari , Joshi Keshava , Kulkarni Krishna , Srinikethan Govindan , Namrata Sampagaon , Kulkarni Manoj , Sadarahalli Aishwaraya
Published: December 2022

In India, particulate matter (PM10) shows very strong persistence and very high levels in most of the tier-II cities along with metropolitan cities and other cities of the world. The present work was to study air pollution (PM10) in Hubli-Dharwad, a tier-II city of Karnataka, India. The mean mass concentration for PM10 varied from 260-410 ppm, substantially higher than guidelines of CPCB. Seasonal variations of these pollutants indicated that higher concentrations of pollutants were observed in summer than in winter seasons with air quality index (AQI) as 211 in summer. The source apportionment study using positive matrix factorization (PMF5) indicated the presence of heavy metals in the atmosphere. Out of 4 identified factors, motor vehicles contributed vastly (38.8%), dust (16.4%), industrial emission (19.8%) and biomass burning (25.0%). This study has found that the source apportionment has distinct regional and seasonal characteristics. Such studies are essential for the Government to make region specific control strategies for particulate pollution in India.
Anticonvulsant activity of 2-amino-4-chloro-6-methyl pyrimidine derivatives: synthesis and characterization
Authors: Guruswamy Vinay , Bantal Veeresh , Lingappa Mallesha
Published: December 2022

A series of new 2-amino-4-chloro-6-methylpyrimidine derivatives, 3(a-f) was synthesized by using different aryl aldehydes. The synthesized compounds were characterized by FT-IR and 1H NMR spectral studies. The maximal electroshock seizure (MES) model was used for anticonvulsant activity and phenytoin was used as standard drug. The rotorod test for neurotoxic effects was determined. Compound 3e was found to be most potent of this series. The compound 3e showed 65.10% protection in comparison to phenytoin which completely inhibited the convulsions produced by electro-convulsometer, Similarly, compound 3a showed moderate protective effects.
Multi-media filtration for pollutant removal in mud crab hatchery wastewater
Authors: Che Harun Mohammad Hakim , Hamzah Sofiah , Mohd Daud Filzah Zahirah , Yatim Norhafiza Ilyana , Ali Nora'aini
Published: December 2022

Aquaculture wastewater consists of uneaten fish feed, faeces other excrement and chemical waste. Discharge of aquaculture wastewater directly into the water stream without treatment can harm the ecosystem. Thus, this study aimed to develop a low-cost filtration system for the treatment of mud crab hatchery wastewater. Sponge was used to pre-treat the wastewater mainly to remove larger particles and suspended solids. Sand and zeolite (with and without heat treatment) were used as filter media for the treatment process. FTIR and SEM analysis determined the morphology and surface chemistry of zeolite which acted as an adsorbent in this process. The physical (temperature, TSS and turbidity) and chemical characteristics (pH, ammonia, TDS and DO) of raw wastewater were determined. The removal efficiency of pollutant for each media used in the filtration system was assessed. From observation, it showed that filter media with heat treatment induced better pollutant removal compared to untreated media. It successfully removed TSS, ammonia and turbidity of wastewater around 18.8%, 90.7% and 100% respectively. It was concluded that the filtration media with heat treament is needed for better pollutant removal in the mud crab hatchery wastewater.
Use of benthic population and embryo-larval development stages of the sea urchin Paracentrotus lividus for evaluating the ecological quality of the west Moroccan Mediterranean coast
Authors: Fouad Meriem , Benhra Ali , Bouhallaoui Mina , El Haimeur Bouchra , Bessi Hlima
Published: December 2022

Moroccan Mediterranean coast is tending to become overused due to urbanization, industrial, fishing and leisure activities; thus, the sea is the final receptacle for nuisances developed. Ecological assessment of aquatic systems using biological indicators has been frequently used to assess water quality. Benthic populations are good indicators of the state of their environment because of their sedentary lifestyle and the diversity of their quick responses to different sources of disturbance. Biological tests on sea urchins are widely used to assess contaminants in sediment and effects on health status. Their sensitivity is manifested by disturbances in the reproductive cycle, fertility and larval development. The main objective of this study is to contribute to the evaluation of quality of West Moroccan Mediterranean coast by studying benthic population’s organization and calculation of biological indices first, then studying sediment toxicity using embryotoxicity bioassay on sea urchin Paracentrotus lividus. Results of the evaluation of the environment impact and toxicity of sediments of West Moroccan Mediterranean coast showed that with the exception of a few stations which are of good quality, the ecological status and the quality of the sediments tested range from moderate to poor.
Multicomponent one pot synthesis of Substituted 3,4-Dihydropyrimidin-2-(1H)-ones by Nanocrystalline CeO2
Authors: Patil Vishvanath D. , Salve Amruta M. , Gharat V.D. , Gawand N.
Published: December 2022

One of the most prominent multicomponent reactions (MCRs), Biginelli reaction has been utilized for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones catalyzed one-pot condensation of aldehyde, β- ketoester and urea in presence of ethanol. The present study deals with synthesis of biologically active 3, 4- dihydropyrimidin-2(1H)-ones using nano crystalline CeO2.
Synthesis and Evaluation of Polysulfone/Polyaniline Nanocomposite Reverse Osmosis Membranes using Sodium Butyl Sulfate
Authors: Salah F. Abdellah Ali , Ehab Said Gad
Published: December 2022

The most prevalent problems of the desalination process are the clogging of membranes and their deterioration utilising free chlorine. As a substratum for the active polyamide layer, a mixture of nanocomposite polysulfone/polyaniline was produced. In this work, the use of a simple chemical oxidative polymerisation process was used for nano polyaniline emeraldine salt. In the presence of sodium butyl sulphate, it has been added to the substratum layer of polysulfone (PS) as a hydrophilic agent to increase the composite membrane reverse osmosis characteristics. Nano-particle membranes with XRD, EDX, FT-IR, SEM, particle size distribution and contact angle were studied in both non-modified and modified polyaniline. The membrane efficiency has been assessed using a crossflow filtering device in terms of water flow and salt rejection. The results demonstrated that the water permeability of the nano-composite membrane (65 L/m2/h) was substantially superior to that of the control membrane (56 L/m2/h) without any significant change in the percentage of salt repulsion. Bovine serum albumin (BSA) as fouling model has been studied and sodium hypochlorite is used for the resistance of membranes to biofouling and chlorine degradation. Due to significant electrostatic repulsion between polyaniline PANI and BSA, the modified membrane was more resistant to biofouling and chlorine assault. Increased performance in reverse osmosis of a thin film composite was achieved using the polysulfonepolyaniline nano-composite substrate produced.
COVID-19 Pandemi Sürecinde Düzenli Fiziksel Aktivite Yapan Yetişkinlerin Koronavirüs Fobisi ve Negatif Duygu Durumları Arasındaki İlişki
Authors: ÇİÇEK Güner , IŞIK Özkan
Published: December 2022

Bu çalışmanın amacı COVID-19 pandemi sürecinde düzenli fiziksel aktivite yapan yetişkin bireylerin koronavirüs fobisi ve negatif duygu durumları arasındaki ilişkinin araştırılmasıdır. Bu çalışmaya düzenli fiziksel aktivite yapan kadın (n=202) ve erkek (n=221) olmak üzere toplamda 423 kişi gönüllü olarak katılmıştır. Katılımcıların spor türüne (Bireysel=208, Takım Sporu=97 ve Sağlık Amaçlı Fitness=118) ve ilgilenilen spor düzeylerine göre kişi sayıları (Profesyonel= 79, Amatör= 262, Rekreatif amaçlı=82) belirlenmiştir. Veri toplama aracı olarak, katılımcıların demografik bilgileri için kişisel bilgi formunun yanı sıra COVID-19 Fobisi ölçeği (C19P-S) ve Depresyon, Anksiyete ve Stres (DASS-42) ölçeği online anket yöntemi ile Google anket formu kullanılarak toplanmıştır. Katılımcıların psikolojik, psiko-somatik, sosyal alt boyutları ve COVID-19 fobi ölçek toplam puanlarında cinsiyete göre istatistiksel olarak anlamlı farklılık tespit edilmiştir (p< ,05). Benzer şekilde DAS puanlarında stres puanlarında da cinsiyete göre istatistiksel olarak anlamlı farklılık tespit edilmiştir (p< ,05). COVID-19 fobi ölçek toplam puanında takım sporunun puan ortalaması sağlık amaçlı fitness puan ortalamasından yüksek olduğu ayrıca depresyon ve anksiyete puanlarında ise takım sporunun puan ortalaması bireysel sporcuların puan ortalamasından anlamlı derecede yüksek olarak tespit edilmiştir. Rekreatif olarak sporla ilgilenenlerin anksiyete puanları profesyonel olarak spor yapanlardan anlamlı derecede yüksek olduğu ve katılımcıların COVID-19 fobi tüm alt boyut ve ölçek toplam puanları ile DAS puanları arasında pozitif yönde orta düzeyde anlamlı ilişkiler olduğu tespit edilmiştir (p< ,05). Kadınların COVID-19 korkularının erkeklere göre daha yüksek olduğu, takım sporu yapanların depresyon ve anksiyete puanlarının bireysel spor yapanlara göre daha yüksek olduğu bulunmuştur. Profesyonel sporcuların negatif duygu durum semptomlarının amatör ve rekreatif amaçlı spor yapanlara göre daha düşük seviyede olduğu söylenebilir.
Application of OWL ontologies and LSTM networks in searching for anomalies of time series
Authors: Курило Дмитрий Сергеевич , Дырночкин Александр Александрович , Мошкин Вадим Сергеевич , Ярушкина Надежда Глебовна
Published: December 2022

В статье описаны результаты разработки алгоритма обнаружения аномалий временных рядов с учетом особенностей предметной области. Алгоритм предполагает нахождение прогноза временных рядов с использованием LSTM-сетей, обнаружение аномалий по полученному прогнозу, фильтрацию найденных аномалий в соответствии с возможными отклонениями значений временного ряда от тренда, отраженными в онтологии, и логический вывод результатов поиска с использованием набора SWRL-правил. Эффективность предложенного подхода подтверждена рядом экспериментов, проводимом на бенчмарке данных по работе нефтяных вышек.

The paper describes the results of the development of an algorithm for detecting anomalies in time series, taking into account the specifics of the subject area. The algorithm involves finding a time series forecast using LSTM networks, detecting anomalies based on the obtained forecast, filtering the found anomalies in accordance with possible deviations of the time series values from the trend reflected in the ontology, and logically deriving search results using a set of SWRL rules. The effectiveness of the proposed approach has been confirmed by a number of experiments conducted on the benchmark of data on the operation of oil rigs.
Preventive analytics in safety problems to develop critical infrastructures
Authors: Фридман Александр Яковлевич
Published: December 2022

В настоящей работе предлагается метод ситуационного моделирования промышленно-природных комплексов (ППК) на различных уровнях управления их безопасностью: от решения вопросов стратегического развития систем регионального масштаба и выше до оперативного управления структурой специализированных ППК при необходимости многократного принятия решений на ограниченном наборе известных альтернатив. Метод обеспечивает интеллектуализированную расчетно-логическую обработку информации о разнотипных характеристиках подобных комплексов с возможностью их анализа и сравнения в статике и динамике. Актуальность работы определяется усложнением ППК в современном мире и усилением их влияния друг на друга, а с другой стороны - появлением больших объемов дополнительных сведений о поведении ППК в связи с ускоряющимся развитием Интернета вещей. Новизна подхода заключается в унификации применения инструментов исследования сложных нестационарных структур в рамках причинно-следственной парадигмы, а также в ориентации на применение экспертных знаний для постановки и решения задач многокритериального сопоставления и выбора предпочтительных вариантов структуры ППК. Полученные альтернативы при необходимости можно дополнительно исследовать их имитацией с использованием специализированных для решения задач безопасности цифровых двойников компонентов ППК.

This paper proposes a method for situational modeling of industrial-natural complexes (INCs) at various levels of their safety management: from solving issues of strategic development for systems of a regional scale and above to operative control of the structure for specialized INCs when multiple decision-making is required on a limited set of known alternatives. The method provides an intellectualized computational-logical processing of information regarding different types of characteristics of such complexes with the possibility of their analysis and comparison in statics and dynamics. The relevance of the work is determined by the complication of INCs in the modern world with the resulted strengthening of their influence on each other, and on the other hand, by the emergence of large amounts of additional information about the behavior of INCs in connection with the accelerating development of the Internet of Things. The novelty of the proposed approach lies in unification of using tools for studying complex non-stationary structures within the framework of the cause-and-effect paradigm, as well as in focusing on applying expert knowledge for setting and solving problems of multi-criteria comparison and selection of preferred options for the structure of an INC. The resulting alternatives, if necessary, can be further investigated in more detail by their imitation with using digital twins of INC’s components specialized for solving safety problems.
Number of maximal rooted trees in uniform attachment model via stochastic approximation
Authors: Малышкин Юрий Андреевич
Published: December 2022

В статье исследуется ассимптотическое поведение числа максимальных деревьев в модели графов равномерного присоединения. В предлагаемой модели рассматривается последовательность графов, которая строится по следующему реккурсивному правилу. Мы начинаем построение с полного графа на $m+1$ вершине, $m>1$. Затем на $n+1$-ом шаге мы добавляем вершину $n+1$ и проводим из нее $m$ ребер в разные вершины, выбранные равномерно из вершин $1,\ldots,n$. В статье получен результат о скорости сходимости числа максимальных деревьев в указанной модели с помощью стохастической аппроксимации.

We study the asymptotic behavior of the number of maximal trees in a uniform attachment model. In our model, we consider a sequence of graphs built by the following recursive rule. We start with the complete graph on $m+1$ vertices, $m>1$. Then on the $n+1$ step, we add vertex $n+1$ and draw $m$ edges from it to different vertices, chosen uniformly from $1,\ldots,n$. We prove the convergence speed for the number of maximal trees in such a model using the stochastic approximation technique.
On the organizations' risk reserves comparison based on the deficiency concept
Authors: Бенинг Владимир Евгеньевич
Published: December 2022

В работе рассмотрено асимптотическое поведение резерва организации, подверженной риску в случае, когда число факторов, приводящих к убытку, случайно. Помимо новых результатов работа содержит обзор последних результатов автора, касающихся асимптотического поведения резервов страховых компаний. Проведено асимптотическое сравнение деятельности таких организаций в терминах необходимого добавочного числа таких факторов. Рассмотрены два примера, иллюстрирующие полученные результаты. Первый пример касается сумм независимых случайных величин, а во втором рассматривается трёхточечное симметричное распределение и распределение Пуассона.

The paper considers the asymptotic behavior of the reserve of an organization exposed to risk in the case when the number of factors leading to a loss is random. In addition to the new results, the paper contains an overview of the author's recent results concerning the asymptotic behavior of insurance company reserves. An asymptotic comparison of the activities of such organizations is carried out in terms of the necessary additional number of such factors. Two examples illustrating the obtained results are considered. The first example concerns sums of independent random variables, and the second one deals with a three-point symmetric distribution and a Poisson distribution.
Various length step calculation method for piecewise linear approximation problem of empirical nonlinear function with a specified accuracy
Authors: Мингалиев Заид Зульфатович , Новикова Светлана Владимировна , Моисеев Георгий Викторович
Published: December 2022

В работе предложен численный метод адаптивного подбора переменного шага для аппроксимации нелинейной одномерной функции, аналитическое выражение которой не задано, кусочно-линейной функцией. Показано, что в условиях миниатюризации вычислительных устройств, подбор шага (сетки) аппроксимации является важной задачей в плане минимизации необходимого количества вычислений. Разработанный алгоритм включает вычисление длин последовательных интервалов, покрывающих в итоге всю область определения функции, с заранее заданной точностью аппроксимации. В качестве меры точности использован коэффициент детерминации. Приведены численные эксперименты, проведено сравнение предложенного метода с методом с постоянным шагом, обеспечивающим ту же точность, выраженную также в значении коэффициента детерминации. Проведенный вычислительный эксперимент доказал преимущество разработанного метода по вычислительным затратам при той же точности.

The paper proposes a numerical method for adaptive selection of a variable step for approximating a nonlinear one-dimensional function, the analytical expression of which is not given, by a piecewise linear function. It is shown that under the conditions of miniaturization of computing devices, the selection of the approximation step (grid) is an important task in terms of minimizing the required number of calculations. The developed algorithm includes the calculation of the lengths of successive intervals, which eventually cover the entire domain of the function, with a predetermined approximation accuracy. The coefficient of determination is used as a measure of accuracy. Numerical experiments are presented, the proposed method is compared with the method with a constant step, providing the same accuracy, also expressed in the value of the coefficient of determination. The conducted computational experiment proved the advantage of the developed method in terms of computational costs with the same accuracy.
On irrotational vector fields with vector lines located on a given surface
Authors: Ульянов Олег Николаевич , Рубина Людмила Ильинична
Published: December 2022

Рассматриваются безвихревые векторные поля на поверхности, заданной уравнением $a=z+\alpha(x,y,t)=0$. Изучаются условия, при выполнении которых векторные линии таких полей располагаются на этой поверхности. Получены достаточные условия существования гармонического векторного поля с такими векторными линиями. Изучена переопределенная система уравнений в частных производных, решение которой обеспечивает получение гармонического поля, векторные линии которого лежат на заданной поверхности рассматриваемого вида. Выписано уравнение поверхности, для которой можно найти гармоническое векторное поле с векторными линиями расположенными на этой поверхности. Показано, что для любых поверхностей рассматриваемого вида можно найти безвихревые негармонические векторные поля с векторными линиями, расположенными на заданной поверхности. Приведен ряд поверхностей, для которых указаны гармонические или негармонические безвихревые векторные поля с векторными линиями расположенными на этих поверхностях. Рассмотрена система уравнений Навье - Стокса для вязкой несжимаемой жидкости в безразмерном виде. Для этой системы в предположении потенциальности поля скоростей выписано частное решение, обеспечивающее расположение векторных линии поля скоростей на параболоиде вращения.

Irrotational vector fields are considered on the surface given by the equation $a=z+\alpha(x,y,t)=0$. The conditions under which the vector lines of such fields are located on this surface are studied. Sufficient conditions for the existence of a harmonic vector field with such vector lines are obtained. An overdetermined system of partial differential equations is studied, the solution of which provides a harmonic field, the vector lines of which lie on a given surface of the considered type. The equation of the surface is written, for which it is possible to find a harmonic vector field with vector lines located on this surface. It is shown that for any surfaces of the type under consideration, one can find irrotational nonharmonic vector fields with vector lines located on a given surface. A number of surfaces are given for which harmonic or nonharmonic irrotational vector fields with vector lines located on these surfaces are obtained. Navier - Stokes equations for a viscous incompressible fluid in nondimensional form are considered. For this system, under the assumption that the velocity field is potential, a particular solution is written that ensures the location of the vector lines of the velocity field on a paraboloid of revolution.
On decidability of finite subsets’ theory for discrete linear order
Authors: Авхимович Николь Вадимовна
Published: December 2022

Мы рассматриваем метод построения новых алгебраических систем как конечных подмножеств уже существующих. Берем исходные системы, обладающие дискретным линейным порядком, и вводим на них новое отношение для конечных подмножеств. Считаем, что два подмножества состоят в новом отношении тогда и только тогда, когда каждый элемент первого подмножества меньше каждого элемента второго. Для теорий таких систем мы доказываем, что они допускают эффективную элиминацию кванторов. Следовательно, такие теории являются разрешимыми.

Let us consider a discrete linear ordered set. On finite subsets of such set we introduce a new binary relation. This relation says that all items of a first set is less than all items of a second one. We show that the theory of such constructed structure admits quantifier elimination. For this purpose, we expand the language with four definable functions. As a corollary we get the theory of finite subsets of a discrete linear order to be decidable.
PENINGKATAN NILAI EKONOMIS LIMBAH KULIT KELAPA MELALUI PRODUK KERAJINAN LAMPU TIDUR
Authors: Rahmawati Vivi
Published: December 2022

Kegiatan ini adalah bagian dari upaya kreativitas dosen dan mahasiswa yang bertujuan untuk mengubah limbah kelapa muda menjadi barang yang bernilai ekonomis sehingga bermanfaat bagi masyarakat khususnya mahasiswa. Produk yang dihasilkan adalah lampu tidur unik dengan banyak fungsi yang terbuat dari limbah kulit kelapa muda yang disebut Tricor. Kegiatan ini melibatkan kelompok pedagang kelapa muda yang ada di kota Jombang sebagai mitra peneydia bahan baku. Kegiatan ini dilakukan dengan intensif oleh penulis selama kurang lebih empat bulan mulai Juni – September 2022. Rangakain kegiatan diawali dengan survey pendahuluan untuk peluang usaha, ketersediaan bahan baku, praktik pembuatan lampu Tricor, hingga manajemen usaha. Dari hasil kegiatan diketahui bahwa usaha pembuatan lampu tidur Tricor layak untuk dikembangkan. Hal ini karena: 1) Pembuatan lampu Tricor relatif mudah; 2) Peluang bisnis juga masih terbuka lebar karena belum banyak pesaing.; 3) Mengurangi limbah buah kelapa; 4) Mampu membantu meningkatkan perekonomian jika dikelola secara baik.
PELATIHAN PENGOLAHAN SINGKONG MENJADI OLAHAN MAKANAN BERVARIASI GUNA MENINGKATKAN PEREKONOMIAN KELUARGA
Authors: Kurniasih Eem , Masduki Lusi Rachmiazasi , Dalyono Bambang
Published: December 2022

This community service activity aims to increase cassava processing skills into various variations of food made from cassava (cassava). This activity involved members of the Family Welfare Empowerment in Jaten Village, Karanganyar - Surakarta as foster partners. This activity lasted for six months intensively with an intensive training model accompanied by the provision of supporting materials. From the results of the training, the fostered partners were able to absorb the material provided well. Supported partners can process food made from cassava into several variations of food that have economic value so that they can be sold to increase family income.
PENINGKATAN KAPASITAS KARYAWAN DI BIDANG AKUNTANSI PADA YAYASAN CEMPAKA EDUCATION CENTER PRIGEN
Authors: Lusy Lusy , Hermanto Y. Budi , Widyastuti Maria , Surya Yohanes Candra
Published: December 2022

Pelaksanaan Kegiatan Pengabdian Kepada Masyarakat (PKM) ini dilakukan sebagai bagian dari Tri Darma Perguruan Tinggi. Kegiatan ini berupa pendampingan dan pelatihan intensif kepada staf di bagian Akuntansi Yayasan Cempaka Education Center guna untuk menghasilkan laporan keuangan berkualitas, sesuai Implementasi Standar Akuntansi Keuangan 35. Kegiatan ini dilakukan secara intensif selama kurang lebih selama dua bulan. Kegiatan yang dilakukan berupa: pelatihan intensif pengelompokan Chart of Account (COA); penyusunan laporan keuangan; diskusi dan pencarian solusi terkait laporan keuangan tidak tepat waktu dalam penyajiannya. Hasil kegiatan PKM sangat bagus. Mitra binaan mampu menyusun COA sesuai ISAK 35, konsisten dalam pengelompokan akun, serta pengaturan waktu pengerjaan laporan keuangan menjadi lebih baik.
EFFECTIVENESS AND CONTRIBUTION OF PUBLIC SERVICE RETRIBUTIONS TO REGIONAL REVENUE IN JOMBANG
Authors: Sucipto Hadi
Published: December 2022

This study aims to determine the Effectiveness and Contribution of public service fees to receiving local revenue in Jombang Regency. This study uses a quantitative approach. The data used is secondary data originating from reports on the realization of the Jombang Regency regional revenue and expenditure budget for 2018-2020. The results showed that the level of Effectiveness of general service fees for the 2018 period was quite effective, with a percentage of 87%; in 2019, it was in the effective category with a percentage of 99%; in 2020, it was in the category quite effective with a percentage of 80%. Meanwhile, the Contribution of public service fees to local revenue receipts for 2018 to 2020 is very lacking, with the percentage in 2018 at 8%, in 2019 at 6%, and in 2020 at 3%.

Keywords: Effectiveness, Contribution, Public Service Retribution, Regional Original Revenue, Jombang
THE ROLE OF AMAZEMENT ON SPIRITUAL TOURISM OF THE KE'TE KESU ANCESTRAL CEMETERY
Authors: Pratiwi Nur , Sudiro Achmad , Fatchurrohman Fatchurrohman , Sabil Hussain Ananda
Published: December 2022

This study aims to examine the structural model that integrates the variables of experience quality, amazemet and behavioral intention. The variable of amazement is the development of the concept of positive emotions, and the context of spiritual tourism is a research context that has not been studied much. This research was conducted in the ancient cemetery of the ancestors of the Toraja Ke'te Kesu tribe. 300 questionnaires were collected in this study and processed using the PLS technique with the help of smart PLS. The results of this study indicate that the Quality of experience and Amazement are antecedents of behavioral intentions, and amazement plays a role in partially mediating the relationship between experience quality and behavioral intentions.
ANALISIS KEPEMILIKAN KELUARGA DAN HUTANG TERHADAP KEBIJAKAN DIVIDEN DALAM PERUSAHAAN KELUARGA
Authors: Willius Calvin , Widyastuti Maria
Published: December 2022

This study aims to examine dividend policy in the context of internal and external corporate governance mechanisms of family firms in Indonesia. This type of research data is quantitative research. The object in this study is a family firm listed in the Indonesia Stock Exchange (IDX) during the period of 2016-2020. The sample selection of this research used the purposive sampling method with a total sample of 69 family firms. The results indicate that the concentration of family ownership has a relationship to dividend policy and debt has no significant impact to dividend policy.
GAMBARAN UMUM KONDISI PEKERJA ONLINE DI JABODETABEK
Authors: Tejo Joseph Haryo , Wendra Wendra
Published: December 2022

Kondisi pandemi Covid-19 membuat perubahan pada kehidupan masyarakat, termasuk dalam hal bekerja. Model bekerja yang awalnya dilakukan secara konvensional berubah menjadi kombinasi online (bekerja dari rumah) dan bekerja dari kantor, bahkan ada yang full online. Perubahan ini menuntut meningkatkan kemampuan (soft skill dan hard skill) serta berpengaruh terhadap psikologis seseorang baik dari segi kepuasan kerja, kelelahan kerja, dan rasa keterikatan karyawan. Tujuan penelitian ini adalah untuk mengidentifikasi pengaruh tuntutan kerja terhadap kepuasan kerja dan keterikatan karyawan dengan menyisipkan variabel kelelahan kerja sebagai mediasi. Penelitian yang dilakukan bersifat kuantitatif dengan menyebarkan kuesioner secara purposive terhadap 100 responden yang bekerja secara online di daerah Jabodetabek. Hasil penelitian menemukan bahwa tuntutan kerja memiliki pengaruh negatif dan signifikan pada kepuasan kerja. Tuntutan kerja ini memiliki pengaruh negatif dan signifikan pada keterikatan karyawan. Kelelehan kerja mampu memediasi hubungan antara tuntutan kerja dengan keterikatan karyawan. Namun, kelelahan kerja tidak dapat memediasi hubungan antara tuntutan kerja terhadap kepuasan kerja.
KINERJA TENAGA KESEHATAN RSUD DR. WAHIDIN SUDIRO HUSODO KOTA MOJOKERTO
Authors: Fitriani Azizah , Yuliani Anisa , Krishernawan Indra
Published: December 2022

The purpose of this research is to evaluate the impact of occupational health and safety, compensation and work discipline on the performance of health workers in RSUD Dr. Wahidin Sudiro Husodo the city of Mojokerto. This study uses a quantitative approach. The data used is primary data sourced from questionnaires distributed to 71 health workers as respondents. The analyzer uses Multiple Linear Regression. From the results of the analysis it was found that OSH and work discipline contributed to changes in the performance of health workers. However, compensation has no significant effect on the performance of health workers.
PERAN MEDIASI OCB PADA PENGARUH THE BIGJFIVE PERSONALITY TERHADAP KINERJA PERAWAT RSUD DR. SOEDIRMAN KEBUMEN
Authors: Prasetyo Anton
Published: December 2022

Organizational Citizenship Behavior (OCB) has an important role in organizational effectiveness because basically OCB attitudes can improve organizational performance. This study aims to determine and test the bigative personality effect on performance with OCB as a mediating variable in nurses at RSUD dr. Soedirman Kebumen. This study uses a quantitative approach. The data used is primary data in the form of questionnaire answers from 155 respondents. The analysis tool uses the Partial Least Square Structural Equation Model (PLS-SEM) analysis. The results of the analysis show that the big five personality dimensions, namely extraversion, acceptance, conscientiousness, oneuroticism and openness to experience have a positive and significant effect on OCB; the dimensions of extraversion, conscientiousness and openness to experience have a positive and significant effect on performance, while the dimensions of agreeableness and neuroticism have no effect on performance; OCB has a positive and significant influence on performance; and OCB were able to mediate the effect of agreeableness, conscientiousness, and openness to experience on performance, and OCB could not mediate the effect of extraversion and neuroticism on performance.
RESOURCE-BASED VIEW: STRATEGI UMKM DI SUMATERA BARAT UNTUK MENCAPAI KEUNGGULAN KOMPETITIF
Authors: Aisyah Hesty , Puspita Sari , Elizamiharti Elizamiharti
Published: December 2022

West Sumatra has a number of MSMEs that tend to increase every year. However, these MSMEs are still lacking confidence because of the limitations they have, such as difficulties in funding, lack of technological tools to support operational activities, and lack of knowledge in the scope of business strategy. This research is a type of empirical research in the form of a literature study originating from five previous studies. The keywords used in the selection of articles were: 1) 2019-2020 criteria, 2) discussing MSMEs, 3) using the Resource-Based View (RBV) strategy, 4) using the VRIO theory (valuable, rare, inimitable, organization). From the research results, it was found that RBV with VRIO analysis contributed positively to MSMEs in gaining competitive advantage. Valuable, rare, imitability and organization are internal assets or resources owned by tangible and intangible MSMEs. VRIO optimally contributes to competitive advantage if applied together to strengthen one another.
RISK MANAGEMENT IN ISLAMIC FINANCIAL TECHNOLOGY
Authors: Umari Abdurrahim Abi Anwar  , Sakova Megha , Solikin Ikin , Asni Mustika Rani
Published: December 2022

Digital developments have encouraged the development of financial technology (fintech) companies in the world, including fintech that upholds sharia principles. Until 2022, there are only seven sharia fintech companies registered with the Financial Services Authority (FSA/OJK) in Indonesia. Awareness of sharia products/services is still very small and tends to grow slowly. One way to catch up with Islamic fintech is to manage risk management. This is important to provide safe and comfortable services for consumers. The purpose of this study is to describe risk management and risk mitigation in Islamic fintech. This research is a literature study using secondary data in the form of journal articles published in reputable international journals. From the research results it is known that the importance of implementing risk management in Islamic fintech is closely related to technology risk. After all, the system is a media platform with connected hardware and software using the internet as an open trading system. The application of technology risk management needs to be adjusted to the objectives and policies of the digital financing business strategy (complexity).