bluuebunny/crossref_metadata_2025 huggingface dataset:
القيادة الرقمية على الاستعداد للتغيير في قطاع التعليم العالي في فلسطين: نموذج مقترح
Authors: Abuajwa Abdallah H. , Ali Al-Tahitah Ali Nasser , Abdul Muthaliff Mohamed Mihlar
Published: December 2023

: تُعد القيادة الرقمية من أهم المفاهيم الإدارية الحديثة التي تساهم في تطوير وتحسين وضمان استمرار للمنظمات في أداء رسالتها ومهامها على اختلاف أهدافها وتصنيفاتها، وهي تهدف بشكل رئيس إلى توفير البيئة المناسبة لإحداث تغييرات تكنولوجية في بيئة العمل هدفها التعامل مع متطلبات العصر التكنولوجي الحالي من خلال توظيف التكنولوجيا الحديثة من أجل تطوير وتحسين العمل ورفع كفاءة العاملين مما يرفع ذلك من كفاءة هذه المؤسسات لاسيما في الوقت الذي أصبح استعمال التكنولوجيا من الأولويات في ظل التغيير المتسارع في بيئة المنظمات، وعليه تهدف هذه الورقة إلى تسليط الضوء على مفاهيم القيادة الرقمية وكذلك علاقتها بالاستعداد للتغيير وواقعها في مؤسسات التعليم العالي بغزة - فلسطين، من خلال مراجعة أدبيات الدراسات السابقة ذات العلاقة بموضوع الدراسة، هذا ويتكون مجتمع الدراسة من العاملين في هذه المؤسسات ، وعينة الدراسة هم العاملين ذوي المسميات الإشرافية في الفترة الزمنية 2020 -2023 ، وعليه سيتم اختيار عينة عشوائية بسيطة من المبحوثين كما سيتم استخدام برنامج (SPSS) لمناقشة واختبار الفرضيات ونموذج الدراسة، وسيتم الاعتماد على المنهج الوصفي التحليلي لإجراء الدراسة لملائمته لأغراض وطبيعة الدراسة وأهدافها، حيث ستستخدم الاستبانة كأداة رئيسة لجمع البيانات بغرض تحليلها ومعالجتها وصولاً للنتائج المرجوة، ومن المتوقع أن تجد الدراسة الحالية تأثير إيجابي للقيادة الرقمية على الاستعداد للتغيير في مؤسسات التعليم العالي بغزة – فلسطين. وان تشكل هذه الدراسة مرجع حقيقي للمؤسسات محل الدراسة.

Digital leadership is one of the most critical modern management concepts contributing to the development, improvement, and sustainability of organizations in fulfilling their missions and tasks across different goals and classifications. Its primary aim is to create a suitable environment for introducing technological changes into the work environment, addressing the current technological requirements by employing modern technology to enhance and develop work processes and boost the efficiency of employees. This elevates the efficiency of institutions, especially in a time when the use of technology has become a priority amid rapid changes in the organizational environment. However, this paper sheds light on the concepts of digital leadership and its relationship with change readiness in Palestinian higher education institutions in Gaza. It does so by reviewing relevant literature and conducting a study that involves individuals working in these institutions, specifically those holding supervisory positions from 2020 to 2023. The study employs a simple random sample of participants and utilizes the SPSS software to analyze and test hypotheses. The study adopts a descriptive analytical methodology that aligns with its objectives and nature. The primary data collection tool is a questionnaire used to gather, analyze, and process data to reach the desired results. The current study is expected to reveal a positive impact of digital leadership on change readiness in Palestinian higher education institutions in Gaza, serving as a valuable reference for these institutions.
الوقف المبتكر وأثره في التنمية المستدامة- التعليم أنموذجاً: نماذج تطبيقية من دولة الإمارات العربية المتحدة
Authors: AlKarim Hammad Hamza Abed
Published: December 2023

: هدفت هذه الورقة إلى تحليل ماهية الوقف المبتكر، والتأصيل الشرعي لجواز الابتكار في الوقف، ثم عرض أمثلة على شواهد تطور الأوقاف وابتكاراتها في التاريخ الإسلامي، إضافة إلى الربط بين التعليم والتنمية المستدامة، وانتهاء بعرض نماذج تطبيقية للوقف المبتكر في مجال التعليم وتحليلها في دولة الإمارات الإمارات العربية المتحدة، وقد اتبعت الدراسة المنهج الوصفي، وقد بيّنت الدراسة أن الوقف المبتكر هو: الأفكار الجديدة والأصيلة التي يقصد من تطبيقها تطوير الأوقاف من حيث الأصول التي يتم وقفها، ومصارف تلك الأوقاف، وأن عمدة أدلة جواز الابتكار في الوقف هو القياس؛ إذ إن أي صورة جديدة ومبتكرة من صور الوقف يجرى عليها القياس على الأوقاف الثابتة بالنصوص، فإذا استوفت شروط الوقف، ووجدت فيها العلة الجامعة، دون وجود الموانع والنواقض للقياس؛ صح أن تدرج ضمن صور الوقف المشروعة، وقد انتهت كذلك إلى وجود نماذج تطبيقية للأوقاف المبتكرة في الحضارة الإسلامية؛ مثل: وقف الأعراس، ووقف مواساة المريض، ووقف مؤنس المرضى والغرباء، أما فيما يتعلق بالنماذج التطبيقية للوقف المبتكر في مجال التعليم وتطبيقاته في دولة الإمارات العربية المتحدة؛ فقد انتهت الدراسة إلى وجود نماذج عدة تندرج تحت "الوقف المبتكر" وهو نموذج حديث صممه مركز محمد بن راشد العالمي لاستشارات الوقف والهبة؛ والنماذج هي: وقف: قادة الأعمال الشباب للطلاب، ووقف الاستشارة، ووقف قاعات التدريب، ووقف الاستشارات القانونية، ووقف المعرفة، ووقف الثقافة.

 

This paper aims to analyze the nature of innovative waqf, its legal foundation, and present examples of the evolution and innovations within the history of Islamic endowments. Additionally, it links education and sustainable development, concluding with applied models of innovative waqf in education and their analysis in the United Arab Emirates. The study employs a descriptive methodology and demonstrates that innovative waqf encompasses novel and authentic ideas intended for developing endowments in terms of their assets and expenditures. The primary criterion for the permissibility of innovation in waqf is measurement. Any new and innovative form of waqf is assessed against established textual endowments. If it meets the waqf conditions and serves a universal purpose without any impediments, it is considered a legitimate form of waqf. The study also highlights practical examples of innovative waqf in Islamic civilization, such as the endowment for weddings, patient care, and consoling the sick and strangers. Regarding applied models of innovative waqf in education and their applications in the United Arab Emirates, the study identifies several models falling under the category of "Innovative Waqf." A recent model, designed by the Mohammed Bin Rashid Global Centre for Waqf and Endowment Consultancy, includes: Youth Business Leaders for Students Waqf, Consultation Waqf, Training Hall Waqf, Legal Consultation Waqf, Knowledge Waqf, and Cultural Waqf.
A BIBLIOMETRIC STUDY ON TAKAFUL LITERATURE FROM 2000 TO 2023: EMBARKING TOWARD AGRICULTURE PROTECTION
Authors: Adam Malik Nur Salsabila , Sulaiman Syahnaz
Published: December 2023

This study aims to understand the trends of scientific publications related to takaful in the world and to show how authors, institutions, and countries interact with each other in those studies in the field of takaful or Islamic insurance. This study is a quantitative research that employs bibliometric analysis. A time limit was set to examine the current data and the results between the years 2000 to 2023. The journals and articles are acquired from the Scopus scientific database. Overall, there are 321 articles related to the field of takaful were retrieved. This study perceived several variables, including authorship patterns, number of articles published, research approach, geographical affiliation, and subject area. The contribution of this study illustrates that most of the previous studies discussed economic and social development, which are positively influenced by the importance of takaful worldwide. This study finds that the number of takaful literature has increased significantly and consistently over the last 23 years. While there is a positive direction for future research related to takaful areas, however, there is no article produced in the scientific database touching on agriculture takaful. Thus, this will open a vast opportunity for future scientific research collaboration and publications in agriculture takaful. This study also found that Malaysia, Pakistan, Indonesia, Saudi Arabia, and United Kingdom have become the five countries that have played a major role in creating collaborative takaful research. The findings of this study provide important implications for improving the practice of takaful globally.
ANALYSIS OF THE EFFECTIVENESS OF THE BROKER CODE CLOSING POLICY IN RUNNING TRADE ON HERDING BEHAVIOR
Authors: Juwita Ratna , Muryadi Misye Berlianti , Ingriyani Lini
Published: December 2023

The broker code closure policy in running trades carried out by the Indonesia Stock Exchange on December 6, 2021, aims to overcome herding behavior and make better price spreads in the Indonesian capital market. This study aims to determine the policy's success by examining the existence of herding behavior before and after the broker code closure policy is enforced using the Cross-Sectional Absolute Deviation method and by looking at price volatility during the research period. Based on the research that has been carried out, it is known that there is a herding behavior before the policy is implemented, and there is no herding behavior after the policy is enforced. This means that the broker code closure policy in running trades carried out by the Indonesia Stock Exchange has succeeded in overcoming the herding behavior contained in the Indonesian capital market but is still not effective in overcoming price spreads that occur in the Indonesian capital market because there is the market sentiment towards economic conditions that occur both nationally and globally.
MICRO WAQF BANK FOR EMPOWERMENT OF INDONESIAN WOMEN'S MICROECONOMIC AND EFFORTS MINIMIZING THE LOANSHER TRAP
Authors: Fauzi Muhamad , Priatno Adi , Syarjaya Syibli , Dahlan Rahmat
Published: December 2023

Fulfilling household needs for a woman is required to be able to obtain and manage halal-sourced finances from a small and micro-entrepreneur. The trap of conventional and online loan sharks poses a significant risk to the borrower's assets due to the lack of business capital they have in the short term. Establishing a micro waqf bank initiated by the financial services authority in Indonesia aims to provide business financing, assistance and financing sourced from zakat, infaq, sadaqah and waqf relying on Islamic social microfinance institutions. This study aims to analyse micro waqf bank woman customers with small and micro-entrepreneurs to avoid entrapment by a loan shark. The study at the El-Manahij Micro Waqf Bank, Lebak Regency, Banten Province, Indonesia, used qualitative descriptive types through data collection interviews with managers and the head in weekly halaqah. In contrast, data analysis used triangulation: data reduction, display, verification and conclusion. Research shows that most micro waqf bank customers are women with micro-scale enterprises to improve Islamic economy studies. Customers choose micro waqf banks to replace loan sharks providing their business capital and having regular activities in the form of weekly group meetings aimed at knowing business progress, religious studies and gradual loan repayments. Micro waqf bank managers receive pawned valuables with sharia contracts to increase business capital. The customers are responsible for repaying business loans in stages, running social gatherings for customers to obtain excess money and supervising fellow customers. The research implies that getting away from the snares of loan sharks can minimise the burden of living costs where they live. The significant role of micro waqf banks in providing Sharia pawn support is to increase business capital to limit dealing with loan sharks.
MITIGATING INFLATION VIA ISLAMIC FINANCE & ISLAMIC SOCIAL FINANCE
Authors: Mohsin Magda Ismail A. Mohsin
Published: December 2023

The aim of this paper is to highlight the current practices of Islamic Finance IF and Islamic Social Finance ISF in mitigating inflation in Malaysia. This study used a descriptive qualitative method collected from secondary data consisting of documents relate to the subject matter at hand.  The type of documents used are published articles, reports, journals, and websites. Islamic Finance IF & Islamic Social Finance ISF offers various financial products that help to eliminate riba/interest from society, circulate the wealth from the have to the have not in an ethical approach, hence, stabilizing prices and mitigating inflation. This paper is a conceptual study which does not aim to empirically examine the issues but provide successful cases to be adopted by Muslim countries in eliminating riba/interest from their societies and hence mitigating inflation. This paper dose not only presents the Islamic approach in mitigating inflation, but it provides current practical cases in achieving so.  So, this paper will be of great interest to students/researchers/economist/financial institutions and policy makers. Islamic Finance IF & Islamic Social Finance ISF are based on principles deduced from the Quran and Sunnah and which need to be implemented in Muslim societies not only for mitigating inflation but for achieving social justice for all.
WAQF SYSTEM DURING SOUTHEAST ASIA'S DECOLONIZATION PERIOD
Authors: Widiyanti Dwi Retno , Pudjihardjo Muhammad , Ekawaty Marlina , Manzilati Asfi
Published: December 2023

The purpose of this research is to contrast the Waqf systems in Southeast Asian nations with Muslim majorities. This study employs a qualitative literature review methodology. The most frequently cited works listed in trustworthy journals indexed by scopus were used for this study. The analysis of the waqf system in this paper takes place in the years following these nations' independence from colonial rule. The Waqf legal structure and the governing bodies that oversee it are the subject of the study. We selected a number of Southeast Asian nations, including Indonesia, Malaysia, Brunei Darussalam, and Singapore, as our sample of Muslim-majority nations. According to the data, the majority of waqf institutions in Southeast Asia are legitimate.
Proposal for the EU carbon border adjustment mechanism as an instrument of the European Green Deal: possible implications for Poland
Authors: Kawecka-Wyrzykowska Elżbieta
Published: December 2023

The Carbon Border Adjustment Mechanism (CBAM) proposal is one of instruments of the EU Green Deal strategy to reach carbon neutrality by 2050. It provides for a levy on imports based on the amount of carbon emissions resulting from the production of products in question. It introduces a mechanism to establish a level playing field between foreign goods and those produced within the UE internal market in terms of the cost of carbon emissions associated with the production of these goods. In this way, the CBAM would compensate EU producers for the cost of allowances within the ETS and prevent ‘carbon leakage’, it is re-allocation of production abroad, to countries with less ambitious climate goals. Application of the CBAM should also encourage non-EU countries to follow the EU climate policy aimed at reducing GHG emissions and fighting climate warming. The paper elaborates on the concept of the Commission’s proposal and critically assesses it, from the economic point of view (who will lose and who will gain) and in legal terms (compatibility with WTO rules). Also, it identifies possible implications of the CBAM proposal for the Polish and the whole EU economy, as well as for third countries.
Poland’s Settlements with the European Union Budget from May 2004 till the End of 2022, and Funds Available from 2021 to 2027
Authors: Kawecka-Wyrzykowska Elżbieta
Published: December 2023

Among the main benefits from Poland’s membership in the European Union, Poles most often mention the influx of EU funds, an opinion shared by 58% of participants of a 2019 survey by the Public Opinion Research Centre [CBOS, 2019]. In-depth analyses by economists point to accelerated economic development of the country as a primary and permanent benefit of EU membership, which is a direct result not only of EU funds, but first and foremost of Poland’s joining the single European market and the elimination of barriers in the flow of goods, capital, labour, as well as providing services over the large integrated area of the member states [Orłowski, 2021]. However, it is beyond doubt that transfers from the EU budget to Poland have significantly contributed to Poland’s economic standing and social situation since accession, as well as its civilisational development. Positive effects are primarily visible in transport, municipal, educational and cultural infrastructure, the condition of the natural environment, modernisation of certain enterprises, agricultural incomes, competitiveness of agricultural produce, etc. However, the impact of EU funds on the improvement of Poland’s economic competitiveness and innovation has been to a lesser extent than expected [Gorzelak, 2021, pp. 124–135]. Almost 19 years into Poland’s membership, we take a look at Poland’s settlements with the EU budget, both in terms of their absolute value and compared to other countries, as well as with respect to a ‘by type’ structure of transfers and payments to the EU budget in the period 2004-2022. This analysis is supplemented by information on the scale of funds available for Poland under the current multiannual 2021–2027 budget (the so-called Multiannual Financial Framework, MFF). The analysis of a special EU support programme for member states (Next Generation EU, NGEU)1 agreed by the European Council in July 2020 (along with the MFF 2021–2027) was not taken into consideration, because in spring 2023 we still do not know the timing and the amount of funds to be disbursed for Poland. The study ends with a summary, as well as conclusions addressing future challenges related to Poland’s settlements with the EU budget, starting in 2028, after the current multiannual budget expires.
我国高校体育课程思政的研究回溯与未来展望——基于Citespace 的可视化分析
Authors: 刘 定武 , 郭 治辰 , 唐 秘 , 曹 志成 , 何 雨珊
Published: December 2023

为精准把握我国高校体育课程思政研究的发展动态，分析当前领域存在的不足与困阻，探寻未来高校体育课程思政领域发展路向。运用文献资料、可视化分析等研究方法对高校体育课程思政相关科研文献进行知识图谱分析。研究认为，我国高校体育课程思政年发文量总体呈现持续上升趋势，当前正处于迅速增长阶段；研究机构科研互动情况较少，合作不紧密；作者领域尚未形成高产作者群，且合作群体数量少，合作网络还未正式形成；以课程思政、体育课程、高校体育、思政教育、立德树人等高频词组是该领域的研究热点与关注焦点；文献期刊来源分布广泛，但核心期刊载文量较少，高质量理论成果匮乏。为此，要促进国内外研究机构、作者之间的交流与合作，推动高质量学术成果产出与积聚，丰富高校体育课程思政研究内容，推进交叉学科、跨学科研究等方面推动该领域的可持续发展。
高校运动训练专业的发展与展望
Authors: 陈 宙涛
Published: December 2023

本篇文章运用文献资料法和逻辑分析法分析研究中国共产党建党以来领导开展的运动训练专业在社会主义初期、改革开放后社会主义现代化建设新时期和进入新时代的中国特色社会主义建设时期的发展历程、历史逻辑及未来展望。对党领导的运动训练专业的发展进行研究，提出了以下未来发展的建议：一，高校运动训练专业是建设我国加入体育强国的重要推进力。二，高校运动训练专业在高校的重视程度会显著提升，是高校发展的有利抓手。三，高校运动训练专业是培育多功能人才的有利途径。四，高校运动训练专业将成为我国培养竞技体育体系的重要一环。五，高校运动训练专业将是接轨竞技人才与社会的轨道。六，高校运动训练专业的有效开展完善了我国高校竞技赛事的举办。七，高校运动训练专业会显著提升运动员和教练员的综合素养。
极限次数下“慢练”动作对股四头肌力量耐力的影响
Authors: 潘 娣 , 刘 广凯 , 靳 强
Published: December 2023

“慢练”是钢琴等乐器演奏及太极拳等内家拳学习中常用的练习方法，具有独特的功效和价值。力量耐力是跆拳道运动员极为重要的素质之一，对于跆拳道比赛中的动作持续输出起到关键作用。本研究以跆拳道运动员股四头肌力量耐力训练为研究内容，将“慢练”动作引入该训练中，进行为期6周的实验干预，求证“慢练”动作的训练对于肌肉耐力的相关性。研究表明：在极限次数条件下，为期6周的“慢练”动作训练，对于肌肉耐力的增长要优于正常练习速度的力量耐力训练，同时还能在一定程度上促进最大力量的提升。
篮球教练员临场指挥的心理影响因素及应用研究
Authors: 武 泓宇
Published: December 2023

篮球作为当代青少年热爱的体育项目之一，高速度、高强度、激烈对抗逐渐成为新时代篮球发展的方向，作为同场竞技项目其中之一的篮球有着极高的娱乐性和观赏型。在篮球比赛竞争激烈，攻防转换快的背景下人们往往忽视教练员在篮球比赛中发挥的作用，随着篮球运动员技术水平和篮球技战术的快速发展，篮球运动员的专项水平差距日益缩小。篮球运动队的技术及战术水平差异愈小，对教练员的战术安排要求越来越高，要想在比赛中取得理想的成绩，除了日常篮球运动员的自身技战术的训练外，教练员的比赛临场指挥也是重要的环节，临场指挥的好坏决定了篮球教练员的水平，现代篮球比赛不仅是双方队员体能、技能、战术能力等竞技能力的竞争，场下双方教练员心理的博弈以及临场技战术的针对性安排也是比赛决胜的重要因素。本篇文章从运动心理学的角度对篮球教练员的临场指挥心理影响因素进行分析，旨在通过对比赛中的篮球中教练员复杂心理进行探讨研究，为篮球教练员临场心理提供有益参考和帮助。具有重要的实践和理论意义。
СПІВРОБІТНИЦТВО УКРАЇНИ І МІЖНАРОДНОГО КРИМІНАЛЬНОГО СУДУ У СФЕРІ ВІДПОВІДАЛЬНОСТІ ЗА ЗЛОЧИНИ ПРОТИ ЛЮДЯНОСТІ
Authors: Чернецька О. В.
Published: December 2023

Стаття присвячена аналізу співробітництва України і Міжнародного кримі­наль­ного суду у сфері відповідальності за злочини проти людяності. Автором досліджу­ються основні етапи формалізації та нормативного урегулювання взаємовідносин України з МКС. Проаналізована відповідна нормативно-правова база у цій царині. Акцентується увага на тому, що безпека світового правопорядку, ефективність міжнародного права як нормативного регулятора стабільності системи міжнародних відносин, в подальшому неможлива без співробітництва України з Міжнародним кримінальним судом задля уникнення неприпустимості безкарності за злочини проти людяності, які скоює російська федерація.

Автором обґрунтовується необхідність усвідомлення того, що за умов прагнення України до європейського співтовариства та північноатлантичної системи безпеки, ратифікація Римського статусу є необхідною умовою.

Зазначається, що МКС створений як міжнародний механізм для здійснення правосуддя за порушення норм міжнародного права, у випадку, коли держава за різних обставин неспроможна сама належним чином притягнути осіб до кримінальної відповідальності за міжнародні злочини, ратифікація Римського статуту є першочерговим завданням. Звісно, існують певні побоювання та застороги, проте, варто наголосити на тому, що МКС не підміняє національні суди.

Зроблено висновок, що повноцінна правосуб’єктність України на міжнародній мапі неможлива без подальшого створення належних механізмів, які б убезпечили український народ та державу від злочинних посягань та справедливого покарання винних за скоєні злочини проти людяності.
ПРАВОВИЙ ВПЛИВ: ТЕОРЕТИКО-ПРАВОВЕ ДОСЛІДЖЕННЯ
Authors: Шилінгов В. С.
Published: December 2023

Стаття присвячена дослідженню механізму впливу права на суспільне життя, свідомість і поведінку людей. Акцентується увага на тому, що правовий вплив – це складне, комплексне явище, яке розкриває весь процес впливу права в його різноманітті та єдності. Підкреслюється, що предметом правового впливу є всі суспільні відносини, включаючи і ті, які правом безпосередньо не регулюються. У такому сенсі правовий вплив варто розглядати не як дію системи норм, а як реалізацію ідеї права, його «духу». Стверджується, що виокремлення поняття правового впливу у самостійну наукову категорію можливе лише за природньо-правового підходу до розуміння права, тобто на підставі розмежування понять права і закону.

У статті також розглядається співвідношення понять правового впливу та правового регулювання. Наводяться різні погляди науковців-дослідників. Їх узагальнення дає підстави дійти висновку, що право чинить на суспільні відносини не лише суто юридичний вплив, а й діє на них як психологічний, ідеологічний, інформаційний, цінносно-орієнтаційний та мотиваційний чинники.

Автором на підставі здійснених узагальнень сформульовані відповідні висновки, що дало можливість визначити поняття механізму правового впливу як складного соціально-правового явища, що охоплює як правові (зокрема, юридичні), так і неправові (моральні, ідеологічні, психологічні, інформаційні та ін.) засоби впливу на життя суспільства як індивідуальних, так і колективних суб’єктів суспільних відносин.
ERGONOMİK DİSEKSİYON MAKASI
Authors: KESMEZACAR Fahrettin Fatih , MERGEN Atiye Bahar
Published: December 2023

Ergonomi, temel olarak insanın makineye değil makinenin insana uyumunu amaç

edinir. Geleneksel diseksiyon makasları tek bir düzlemde olup, sap ve gövde

bölümlerinde herhangi bir eğim bulunmaz. Bunun sonucunda makası kullanan kişi

sürekli olarak bileğini bükmesine bağlı olarak ağrı ve strese maruz kalır. Standart

makaslarda el nadiren nötr pozisyona gelir. Diseksiyonda dokular kat kat

birbirinden ayrılarak incelenir. Dokuların birbirinden ayrılma işlemi diseksiyon

makasları, oluklu sonda ve bisturi ile yapılır. Ergonomik diseksiyon makasının

tasarımının temel amacı, sap kısmı ve kulplarının insan anatomisine uygun

ergonomik yapıda olmasıdır. Makasın sap bölümde; kulplar ve kulp sapları tamamen

parmak ergonomisine uygun hale getirilmiştir. Ayrıca ergonominin temeli olan aletin

bükülmesi gerekliliği olarak sap bölümü eli nötr pozisyonda kalabilecek şekilde

değiştirilmiştir. Makasın, kulpların bulunduğu sap bölümünde parmaklarla, el bileği

ile ve makas-zeminle olan ilişkileri tasarımda temeli oluşturmuştur. Diseksiyonun

sadece makasla yapılmadığı ve kullanılan diğer aletlerinde makasa nasıl adapte

edileceği de düşünülmüştür. Çalışmada bahsedilen tasarım patent almış ve

tescillenmiştir. Makas ve oluklu sonda aynı malzemede olması kullanıcıya diseksiyon

sırasında oldukça rahatlık sağlayacaktır.
Physical Condition Analysis of Professional Football Players
Authors: Nidomuddin Muhammad , Pamungkas Hari , Yusuf Havid , Husen Ashari , Prasetiyo Rahayu
Published: December 2023

This study aims to determine the level of physical condition level in Nusantara FC players. this research uses descriptive research. Data were analyzed using quantitative analysis in the form of percentages. The population and samples in this study are Nusantara FC totaling 23 professional players who play in League 2 Indonesia. Average physical condition of Nusantara FC players. Speed gets an average result of 4.29, endurance with an average of 56.49 with a lesser category, explosive power gets an average result of 56 with a good category, average flexibility of 19.3 with a good category, and average agility of 7.99 with a good category. The percentage of the physical condition of the players is as follows; speed gets results with a percentage of 78.2% in the good category. The percentage of endurance results is 64% in the less category. Explosive power is 64% with a good category. The results of flexibility with a percentage of 60.8% in the good category. Agility with a percentage of 39.1% in the good category. Analysis of the results of physical conditions is an important part of professional soccer in improving the quality of techniques and tactics in the matches carried out.
ESTUDO COMPARATIVO DE LIGAS A BASE DE NÍQUEL DEPOSITADAS POR ASPERSÃO TÉRMICA
Authors: Farah Alessandro Fraga , Ferreira Breno , Rosa Pedro , Farah Solange
Published: December 2023

aspersão térmica, nas mais diversas áreas de aplicação, a elevada vida útil desses depósitos aspergidos, a possibilidade de reparos imediatos em áreas danificadas e a utilização logo após sua aplicação, são benefícios que tem contribuído para o sucesso desse tipo CWST de revestimento. Para que os benefícios do processo sejam bem aproveitados é importante o desenvolvimento de ligas específicas para resistir às mais diversas condições de serviço, além do aperfeiçoamento dos processos utilizados. O controle de parâmetros tais como porosidade e teor de óxidos quando controlados, melhoram a qualidade do revestimento. Este trabalho tem como objetivo avaliar diferentes ligas de revestimentos à base de Níquel, aspergidas pelos processos de aspersão térmica a arco elétrico e por chama, aplicados em substrato de aço carbono SAE 1020, previamente preparados. As propriedades de dureza do revestimento, características microestruturais e resistência ao desgaste foram avaliadas. Os resultados encontrados neste estudo mostram que a quantidade e distribuição dos carbonetos e a dureza da matriz melhoraram o desempenho dos revestimentos.
DIMENSIONAMENTO DE COLETORES SOLARES PARA PISCINA SEMIOLÍMPICA
Authors: DE JESUS SILVA ANA CAROLINE , NUNES RICHARDSON
Published: December 2023

O crescente aumento na demanda energética mundial é um dos grandes desafios da atualidade. Sabe-se que o uso da energia elétrica para aquecimento de água é um dos maiores responsáveis pelo seu alto consumo no país. Para reduzir esse consumo, uma alternativa viável é popularizar a utilização da energia solar para tal aquecimento. O tema dessa pesquisa é a utilização da energia solar para aquecimento de piscinas semiolímpicas. Foi realizado o dimensionamento em especificação de coletores solares para piscina e suas conexões especiais através de sites de fabricantes de equipamentos. O objetivo desse trabalho foi dimensionar e especificar coletores solares para piscina semiolímpica e fornecer a vazão necessária no sistema. Foi possível concluir que o processo é simples e permite obter informações relevantes e úteis para a posterior elaboração do projeto hidráulico.
Scots and Italy as seen through Alba amicorum, 1540s–1720s Part 2
Authors: Brochard Thomas
Published: December 2023

Part 2 of this article continues its investigation into the relationships between Scots and Italy, as seen through books of friendship, by considering additional socioprofessional categories beyond the academic and military worlds. Among the political activists considered is David Graham of Fintry, a Marian and member of the Catholic party, whose album is studied in great depth. It is a key document for our further knowledge of his activities as a courier and intelligencer for Scottish Catholic interests in Europe and adds to the scholarly understanding of his political involvement in the Counter-Reformation. More broadly speaking, friendship albums shed light on Scottish activists’ politico-religious networking processes and their connections with middle-ranking and regional intermediaries, at times in key locations or seats of power. As with the military officers studied in Part 1, it transpires from these contacts that there were lighter moments for artistic and cultural activities or edification. In correlation, the few ecclesiastical contributions studied in this paper cast light on a fluid matrix of information and networks and highlight their potential influences, both negative and positive. Indeed, there were risks involved in being in contact with dubious characters, whereas tapping into a rich circle of contacts with courtiers could present opportunities and patronage. For Scottish scientists, the genre of alba amicorum is particularly important, not so much to highlight their side activities as to lay the foundations for their subsequent careers and establish the potential links and backgrounds that underscore their subsequent scientific tasks, achievements, and modus operandi in their professional roles.
Old Autocracy or Something New?: Conceptualizing and Measuring Democratic Erosion and Overcoming It
Authors: Somer Murat , Yilmaz Alper
Published: December 2023

Existing measurements of democratic erosion (DE) do not necessarily start with adequate conceptual-theoretical scrutiny and insufficiently incorporate DE’s distinguishing features into operationalizing it. We review existing measurements, offer a definition based on the constitutive characteristics of DE and the roles of oppositions and institutions, and develop new measurement criteria. We show how this changes the population of DE cases in large- and small-N comparative analysis. We argue that recovery from DE should be conceptualized and measured separately from reversals and near-misses, and identify corresponding country episodes. Successful reversals of DE seem to be scarce, and none for countries that endured more than ten years of DE. Successful recoveries is also a small, if not null set. Exceptions are, technically but not necessarily substantively, Ecuador, and substantively but not yet technically, Moldova. DE is a new type of autocratization and polities may need time to learn how to counter it.
Juan de Mena y la construcción de «La Araucana» (con Lucano al fondo)
Authors: Gómez Canseco Luis
Published: December 2023

La imitación que Ercilla hizo del Laberinto de Fortuna no se limitó a versos o episodios concretos. La construcción de La Araucana como poema heroico en torno a la figura de un yo narrador y un tú receptor, que también actúan como personajes, proceden de Juan de Mena, así como la articulación del poema en torno a la historia.
Model order reduction for optimality systems through empirical gramians
Authors: Mechelli Luca , Rohleff Jan , Volkwein Stefan
Published: December 2023

In the present article, optimal control problems for linear parabolic partial differential equations (PDEs) with time-dependent coefficient functions are considered. One of the common approach in literature is to derive the first-order sufficient optimality system and to apply a finite element (FE) discretization. This leads to a specific linear but high-dimensional time variant (LTV) dynamical system. To reduce the size of the LTV system, we apply a tailored reduced order modeling technique based on empirical gramians and derived directly from the first-order optimality system. For testing purpose, we focus on two specific examples: a multiobjective optimization and a closed-loop optimal control problem. Our proposed methodology results to be better performing than a standard proper orthogonal decomposition (POD) approach for the above mentioned examples.
Impact of parity on cow stress, behavior, and production at a farm with guided traffic automatic milking system
Authors: Davis Lindsey , French Elizabeth A. , Aguerre Matias J. , Ali Ahmed
Published: December 2023

The widespread adoption of advanced technology, like automatic milking systems in the United States, allows cows to establish individual milking, feeding, and resting schedules, setting them apart from others. However, it is unknown how cow parity affects cow behavior, stress, and system efficiency. We hypothesized primiparous (PR) cows would spend more time in and around the milking robot (AMS), receive greater agonistic interactions, and show elevated physiological stress behaviors compared to multiparous (MU) cows. The study aimed to evaluate the impact of cow parity on behavior and welfare near and inside the AMS. Twenty-four lactating-Holstein dairy cows [12 primiparous (3.0 ± 0.2 yr) and 12 multiparous (6.1 ± 1.9 yr)] housed in the same pen at a guided traffic AMS facility were marked and observed for 6-consecutive days (91 to 102 of lactation). Study cows were identified by specific colored-paint markings, their milk yield and visits, their behavior, Heart Rate-Variability (HRV), and activity were recorded inside the commitment pen (CP) and the AMS. Statistical calculations were performed using JMP Pro 16.1.0, and P ≤ 0.05 was considered significant. Multiparous cows produced more daily milk yield than PP cows (47.30 Vs 33.79 kg), while parity showed no effect on daily milking frequency or milk yield per visit. Primiparous cows spent significantly more time inside the CP than MP cows (68.87 vs 24.38 m), while MP cows approached the AMS entry more often than the PR cows (4.83 vs 2.03), MU cows displaced other cows more inside the CP than PR cows (6.90 vs 2.59). PR cows showed lower HRV (RMSSD: 9.23 vs 17.58 ms) and (SDRR: 19.58 vs 33.64 ms) values than MU cows, whereas MU cows showed a lower Low-Frequency to High-Frequency Ratio (4.39 vs 8.65) than PR cows inside the CP. MU cows spent more time (m) lying (698.06), particularly at night (396.57), than PP cows (556.96, 286.68), while MP cows exhibited more prolonged total lying bouts than PP cows (93.06 vs 71.32 m). Overall, cow parity influenced behavior, activity, and stress indicators of primiparous more than multiparous cows and impacted the overall efficiency and success of the AMS
Granular activated carbon enhances volatile fatty acid production in the anaerobic fermentation of garden wastes
Authors: Chen Wenwen , Zeng Yiwei , Liu Huanying , Sun Dezhi , Liu Xinying , Xu Haiyu , Wu Hongbin , Qiu Bin , Dang Yan
Published: December 2023

Garden waste, one type of lignocellulosic biomass, holds significant potential for the production of volatile fatty acids (VFAs) through anaerobic fermentation. However, the hydrolysis efficiency of garden waste is limited by the inherent recalcitrance, which further influences VFA production. Granular activated carbon (GAC) could promote hydrolysis and acidogenesis efficiency during anaerobic fermentation. This study developed a strategy to use GAC to enhance the anaerobic fermentation of garden waste without any complex pretreatments and extra enzymes. The results showed that GAC addition could improve VFA production, especially acetate, and reach the maximum total VFA yield of 191.55 mg/g VSadded, which increased by 27.35% compared to the control group. The highest VFA/sCOD value of 70.01% was attained in the GAC-amended group, whereas the control group only reached 49.35%, indicating a better hydrolysis and acidogenesis capacity attributed to the addition of GAC. Microbial community results revealed that GAC addition promoted the enrichment of Caproiciproducens and Clostridium, which are crucial for anaerobic VFA production. In addition, only the GAC-amended group showed the presence of Sphaerochaeta and Oscillibacter genera, which are associated with electron transfer processes. Metagenomics analysis indicated that GAC addition improved the abundance of glycoside hydrolases (GHs) and key functional enzymes related to hydrolysis and acidogenesis. Furthermore, the assessment of major genera influencing functional genes in both groups indicated that Sphaerochaeta, Clostridium, and Caproicibacter were the primary contributors to upregulated genes. These findings underscored the significance of employing GAC to enhance the anaerobic fermentation of garden waste, offering a promising approach for sustainable biomass conversion and VFA production.
Fangchinoline alleviates cognitive impairments through enhancing autophagy and mitigating oxidative stress in Alzheimer’s disease models
Authors: Yi Lilin , Luo Man , Wang Maoju , Dong Zhifang , Du Yehong
Published: December 2023

Introduction: Alzheimer’s disease (AD) is a debilitating, progressive, neurodegenerative disorder characterized by the deposition of amyloid-β (Aβ) peptides and subsequent oxidative stress, resulting in a cascade of cytotoxic effects. Fangchinoline (Fan), a bisbenzylisoquinoline alkaloid isolated from traditional Chinese herb Stephania tetrandra S. Moorec, has been reported to possess multiple potent biological activities, including anti-inflammatory and antioxidant properties. However, the potential neuroprotective efficacy of Fan against AD remains unknown.

Methods: N2AAPP cells, the mouse neuroblastoma N2A cells stably transfected with human Swedish mutant APP695, were served as an in vitro AD model. A mouse model of AD was constructed by microinjection of Aβ1–42 peptides into lateral ventricle of WT mice. The neuroprotective effects of Fan on AD were investigated through a combination of Western blot analysis, immunoprecipitation and behavioral assessments.

Results and discussion: It was found that Fan effectively attenuated the amyloidogenic processing of APP by augmenting autophagy and subsequently fostering lysosomal degradation of BACE1 in N2AAPP cells, as reflected by the decrease in P62 levels, concomitant with the increase in Beclin-1 and LC3-II levels. More importantly, Fan significantly ameliorated cognitive impairment in an Aβ1–42-induced mouse model of AD via the induction of autophagy and the inhibition of oxidative stress, as evidenced by an increase in antioxidants including glutathione reductase (GR), total antioxidant capacity (T-AOC), nuclear factor erythroid-2-related factor 2 (Nrf2), heme oxygenase-1 (HO-1), and superoxide dismutase-1 (SOD-1) and a decrease in pro-oxidants including hydrogen peroxide (H2O2) and inducible nitric oxide synthase (i-NOS), coupled with a reduction in apoptosis marker, cleaved caspase-3. Taken together, our study demonstrate that Fan ameliorates cognitive dysfunction through promoting autophagy and mitigating oxidative stress, making it a potential therapeutic agent for AD.
Development and validation of a rabbit model of Pseudomonas aeruginosa non-ventilated pneumonia for preclinical drug development
Authors: Gras Emmanuelle , Vu Trang T. T. , Nguyen Nhu T. Q. , Tran Vuvi G. , Mao Yanjie , Tran Nguyen D. , Mai Nam H. , Dong Oliver X. , Jung David H. , Iorio Natalia L. P. P. , Povoa Helvecio C. C. , Pinheiro Marcos Gabriel , Aguiar-Alves Fabio , Weiss William J. , Zheng Bo , Cheng Lily I. , Stover Charles K. , Sellman Bret R. , DiGiandomenico Antonio , Gibault Laure , Valour Florent , Diep Binh An
Published: December 2023

Background

New drugs targeting antimicrobial resistant pathogens, including Pseudomonas aeruginosa, have been challenging to evaluate in clinical trials, particularly for the non-ventilated hospital-acquired pneumonia and ventilator-associated pneumonia indications. Development of new antibacterial drugs is facilitated by preclinical animal models that could predict clinical efficacy in patients with these infections.

Methods

We report here an FDA-funded study to develop a rabbit model of non-ventilated pneumonia with Pseudomonas aeruginosa by determining the extent to which the natural history of animal disease reproduced human pathophysiology and conducting validation studies to evaluate whether humanized dosing regimens of two antibiotics, meropenem and tobramycin, can halt or reverse disease progression.

Results

In a rabbit model of non-ventilated pneumonia, endobronchial challenge with live P. aeruginosa strain 6206, but not with UV-killed Pa6206, caused acute respiratory distress syndrome, as evidenced by acute lung inflammation, pulmonary edema, hemorrhage, severe hypoxemia, hyperlactatemia, neutropenia, thrombocytopenia, and hypoglycemia, which preceded respiratory failure and death. Pa6206 increased >100-fold in the lungs and then disseminated from there to infect distal organs, including spleen and kidneys. At 5 h post-infection, 67% of Pa6206-challenged rabbits had PaO2 <60 mmHg, corresponding to a clinical cut-off when oxygen therapy would be required. When administered at 5 h post-infection, humanized dosing regimens of tobramycin and meropenem reduced mortality to 17-33%, compared to 100% for saline-treated rabbits (P<0.001 by log-rank tests). For meropenem which exhibits time-dependent bactericidal activity, rabbits treated with a humanized meropenem dosing regimen of 80 mg/kg q2h for 24 h achieved 100% T>MIC, resulting in 75% microbiological clearance rate of Pa6206 from the lungs. For tobramycin which exhibits concentration-dependent killing, rabbits treated with a humanized tobramycin dosing regimen of 8 mg/kg q8h for 24 h achieved Cmax/MIC of 9.8 ± 1.4 at 60 min post-dose, resulting in 50% lung microbiological clearance rate. In contrast, rabbits treated with a single tobramycin dose of 2.5 mg/kg had Cmax/MIC of 7.8 ± 0.8 and 8% (1/12) microbiological clearance rate, indicating that this rabbit model can detect dose-response effects.

Conclusion

The rabbit model may be used to help predict clinical efficacy of new antibacterial drugs for the treatment of non-ventilated P. aeruginosa pneumonia.
The Cornwall Beaver Project: navigating the social-ecological complexity of rewilding as a nature-based solution
Authors: Jones Mike , Jones Chris
Published: December 2023

The story of the Cornwall Beaver Project is presented as the foundation of a review of the literature to consider the effects of beavers on geomorphological and hydrological processes, habitats, biodiversity, and people in agricultural landscapes in the UK. The review includes a comparison of the principles for rewilding as an approach to ecological restoration with IUCNs principles for Nature-based Solutions together with a summary of beaver reintroduction in Europe, and the impacts of beavers on hydrological and geomorphological processes, biodiversity and the human-wildlife conflict that arises from reintroduction. We note that rewilding principles require a paradigm shift in the relationship between humans and the rest of nature and a corresponding application of systems thinking to research, practice and policy. The combination of experiential and formal knowledge is assessed using a social-ecological systems framework to consider the potential of beavers to mitigate climate change impacts on agricultural landscapes in the UK and how rewilders might navigate the social complexity of beaver reintroduction to achieve large scale system transformation. We discuss the different lines of evidence about the impacts of beavers on landscapes as viewed through a system lens and conclude that: (1) beaver dams have considerable potential to store water but their ability to reduce flood risk is difficult to assess because of the complex interactions between the material available for dam construction, geomorphology, and the duration, extent and intensity of rainfall events; (2) beaver dams, especially when combined with buffer zones along water courses have considerable potential to enhance the resilience of agricultural landscapes and support a shift from intensive to agroecological farming; (3) scaling beaver reintroduction will evolve with the application of policies and practices that enhance the ability of land users to adapt and learn how to coexist with beavers. Our review proposes a low conflict strategy for rewilding with beavers that includes changes from a policy of conflict avoidance to a proactive policy to support practices that apply the tools of social-ecological systems science to the body of knowledge about the interactions between beavers and their environment.
Comparing pyrotinib with trastuzumab and pertuzumab with trastuzumab for HER2-positive metastatic breast cancer: a retrospective, multicenter analysis
Authors: You Shuhui , Xie Yizhao , Sang Die , Luo Ting , Yuan Peng , Xu Fei , Wang Biyun
Published: December 2023

Objective

Pyrotinib and pertuzumab are effective treatment options for HER2-positive metastatic breast cancer (HER2+ MBC). Our study was to directly compare the efficacy and safety of pyrotinib plus trastuzumab (PyroH) and pertuzumab plus trastuzumab (HP) in patients with HER2+ MBC.

Methods

We conducted a retrospective examination of HER2+ MBC patients who received PyroH plus chemotherapy or HP plus chemotherapy between 2017 and 2022 at five institutions in China. Our primary endpoint was progression-free survival (PFS).

Results

This study involved 333 patients, among which 161 received PyroH and 172 received HP. The utilization of PyroH as a first-line therapy for MBC was more prevalent among older patients, those with a shorter duration of disease-free interval, or those who had previously been treated with trastuzumab. Although in the first-line advanced treatment HP cohort showed numerically longer PFS (median PFS: 14.46 vs. 22.90 months, p=0.057), in the second-line or later treatments, there was no significant difference in PFS between the PyroH and HP groups (median PFS: 8.67 vs. 7.92 months, p=0.286). Despite HP showing a longer PFS in the overall cohort (median PFS: 9.30 vs. 13.01 months, p=0.005), it did not serve as an independent predictor of PFS in the multivariate analysis (HR 1.134, 95% CI 0.710-1.811, p=0.598). Without taxane, PyroH demonstrated a longer PFS than HP (median PFS: 10.12 vs. 8.15 months, p=0.017). PyroH group displayed a numerically longer median PFS in patients with brain metastases compared to the HP group, though not statistically significant (median PFS: 9.03 vs. 8.15 months, p=0.976). PyroH had higher incidence of grade 3/4 diarrhea (34.3% vs. 3.0%) but similar overall adverse events.

Conclusion

In conclusion, PyroH is comparable in second-line or later treatment and during brain metastasis, even having superior efficacy without taxane in real-world setting. Toxicities were tolerable in both groups. (ClinicalTrials.gov: NCT05572645)
Does climate change drive up government healthcare costs in the European Union?
Authors: Socol Adela , Iuga Horia , Socol Dragoș , Iuga Iulia Cristina
Published: December 2023

The continuous growth in average temperature around the world, caused especially by CO2 emissions, generates climate changes significantly impacts not only economic or social domains, but also human health. The previous literature provides evidence of degradation of human health due to climate change and emphasizes pressure on governments to increase government spending on health. The aim of this study is to analyze the impact of climate change, expressed by temperature and CO2 emissions, on healthcare spending in the European Union member states using available data from 2000 to 2020. In addition to prior research, this paper incorporates supplementary control variables such as governance, macroeconomic factors (GDP and inflation) and human development index. To capture the dynamic impact of climate change on healthcare expenditure, we use the Generalized Method of Moments (GMM) technique and the panel VAR Granger causality method. Empirical findings suggest that an increase in temperature and CO2 emissions levels, along with improvements in governance, economic growth, inflation, and human development, contribute to higher healthcare expenditures. Rising temperature and CO2 emissions are directly increasing the health burden on individuals’ health and force governments to enhance health spending. The paper is notable for its comprehensive approach, filling a significant gap in existing literature by combining climate change variables with governance, economic and human development indicators. The study provides policymakers with valuable insights into how climate change and other governance, economic and human factors impact healthcare spending. Global warming appears as a topic directly correlated with the governmental health spending burden and highlights the need for government involvement in mitigating global warming, reducing pollution and gas emissions.