bluuebunny/crossref_metadata_2025 huggingface dataset:
Characteristics of Snow Particle Size Distribution in the PyeongChang Region of South Korea
Authors: Yu Tiantian , Chandrasekar V. , Xiao Hui , Joshil Shashank S.
Published: October 2020

Snow particle size distribution (PSD) information is important in understanding the microphysics and quantitative precipitation estimation over complex terrain. Measurement and interpretation of the snow PSDs is a topic of active research. This study investigates snow PSDs during 3 year of observations from Parsivel2 disdrometers and precipitation imaging packages (PIP) at five different sites in the PyeongChang region of South Korea. Variabilities in the values of the density of snow (ρ), snowfall rate (S), and ice water content (IWC) are studied. To further understand the characteristics of snow PSD at different density and snowfall rate, the snow particle size distribution measurements are divided into six classes based on the density values of snowfall and five classes based on snowfall rates. The mean shape factors (Dm, log10Nw, and μ) of normalized gamma distribution are also derived based on different density and snowfall rate classes. The Dm decreases and log10Nw and μ increase as the density increases. The Dm and log10Nw increase and μ decreases with the increase of snowfall rate. The power-law relationship between ρ and Dm is obtained and the relationship between S and IWC is also derived.
The Impacts of Aerosol Emissions on Historical Climate in UKESM1
Authors: Seo Jeongbyn , Shim Sungbo , Kwon Sang-Hoon , Boo Kyung-On , Kim Yeon-Hee , O’Connor Fiona , Johnson Ben , Dalvi Mohit , Folberth Gerd , Teixeira Joao , Mulcahy Jane , Hardacre Catherine , Turnock Steven , Woodward Stephanie , Abraham Luke , Keeble James , Griffiths Paul , Archibald Alex , Richardson Mark , Dearden Chris , Carslaw Ken , Williams Jonny , Zeng Guang , Morgenstern Olaf
Published: October 2020

As one of the main drivers for climate change, it is important to understand changes in anthropogenic aerosol emissions and evaluate the climate impact. Anthropogenic aerosols have affected global climate while exerting a much larger influence on regional climate by their short lifetime and heterogeneous spatial distribution. In this study, the effective radiative forcing (ERF), which has been accepted as a useful index for quantifying the effect of climate forcing, was evaluated to understand the effects of aerosol on regional climate over a historical period (1850–2014). Eastern United States (EUS), Western European Union (WEU), and Eastern Central China (ECC), are regions that predominantly emit anthropogenic aerosols and were analyzed using Coupled Model Intercomparison Project 6 (CMIP6) simulations implemented within the framework of the Aerosol Chemistry Model Intercomparison Project (AerChemMIP) in the UK’s Earth System Model (UKESM1). In EUS and WEU, where industrialization occurred relatively earlier, the negative ERF seems to have been recovering in recent decades based on the decreasing trend of aerosol emissions. Conversely, the radiative cooling in ECC seems to be strengthened as aerosol emission continuously increases. These aerosol ERFs have been largely attributed to atmospheric rapid adjustments, driven mainly by aerosol-cloud interactions rather than direct effects of aerosol such as scattering and absorption.
A Review of Blockchain in Internet of Things and AI
Authors: Atlam Hany F. , Azad Muhammad Ajmal , Alzahrani Ahmed G. , Wills Gary
Published: October 2020

The Internet of Things (IoT) represents a new technology that enables both virtual and physical objects to be connected and communicate with each other, and produce new digitized services that improve our quality of life. The IoT system provides several advantages, however, the current centralized architecture introduces numerous issues involving a single point of failure, security, privacy, transparency, and data integrity. These challenges are an obstacle in the way of the future developments of IoT applications. Moving the IoT into one of the distributed ledger technologies may be the correct choice to resolve these issues. Among the common and popular types of distributed ledger technologies is the blockchain. Integrating the IoT with blockchain technology can bring countless benefits. Therefore, this paper provides a comprehensive discussion of integrating the IoT system with blockchain technology. After providing the basics of the IoT system and blockchain technology, a thorough review of integrating the blockchain with the IoT system is presented by highlighting benefits of the integration and how the blockchain can resolve the issues of the IoT system. Then, the blockchain as a service for the IoT is presented to show how various features of blockchain technology can be implemented as a service for various IoT applications. This is followed by discussing the impact of integrating artificial intelligence (AI) on both IoT and blockchain. In the end, future research directions of IoT with blockchain are presented.
An Acute Application of Cerebellar Transcranial Direct Current Stimulation Does Not Improve Motor Performance in Parkinson’s Disease
Authors: Lima de Albuquerque Lidio , Pantovic Milan , Clingo Mitchel , Fischer Katherine , Jalene Sharon , Landers Merrill , Mari Zoltan , Poston Brach
Published: October 2020

Transcranial direct current stimulation of the cerebellum (c-tDCS) improves motor performance in young and old adults. Based on the cerebellar involvement in Parkinson’s disease (PD), c-tDCS could have potential to improve motor function in PD. The purpose was to determine the effects of c-tDCS on motor performance in PD while participants were on medications. The study was a randomized, double-blind, SHAM-controlled, between-subjects design. Twenty-two participants with PD were allocated to either a c-tDCS group or a SHAM group. All participants completed one experimental session and performed two motor tasks with their most affected hand in a Baseline condition (no stimulation) and an Experimental condition. The motor tasks were a visuomotor isometric precision grip task (PGT) and a rapid arm movement task (AMT). The primary dependent variables were force error and endpoint error in the PGT and AMT, respectively. There were no significant differences in force error or endpoint error in the Experimental condition between the c-tDCS and SHAM groups. These results indicate that an acute application of c-tDCS does not enhance motor performance in hand and arm tasks in PD. Longer-term c-tDCS application over multiple days may be needed to enhance motor function in PD.
What about “Pharming”? Issues Regarding the Misuse of Prescription and Over-the-Counter Drugs
Authors: Chiappini Stefania , Schifano Fabrizio
Published: October 2020

Recently, a range of prescription and over-the-counter (OTC) drugs have emerged as being used recreationally, either on their own or in combination with other substances, both licit and illicit, including new psychoactive substances (NPS). Among them, the misuse of prescription drugs involves not only traditionally recorded substances, such as benzodiazepines and opioid pain relievers, but also gabapentinoids (e.g., pregabalin and gabapentin); some antidepressants, e.g., bupropion and venlafaxine; some second-generation antipsychotics, e.g., quetiapine and olanzapine. Moreover, the use of some OTC for recreational purposes appears on the increase, especially in vulnerable categories such as young people/youths, including the use of high dosages of the antidiarrheal loperamide; first-generation antihistamines, e.g., promethazine, cyclizine, and diphenhydramine; cough and cold preparations containing dextromethorphan and/or codeine. In this context, the role of the Internet has rapidly increased, playing a significant role both in the diffusion of emerging trends of drug misuse among users and experimenters, and the marketing, sale, and distribution of drugs through online pharmacies. This phenomenon within the context of a rapidly modifying drug scenario is a globally recognized health problem, determining severe adverse consequences, including fatalities, and represents a challenge for clinicians in general, psychiatrists, public health, and drug-control policies.
Semantics Based on the Physical Characteristics of Facial Expressions Used to Produce Japanese Vowels
Authors: Namba Shushi , Kambara Toshimune
Published: October 2020

Previous studies have reported that verbal sounds are associated—non-arbitrarily—with specific meanings (e.g., sound symbolism and onomatopoeia), including visual forms of information such as facial expressions; however, it remains unclear how mouth shapes used to utter each vowel create our semantic impressions. We asked 81 Japanese participants to evaluate mouth shapes associated with five Japanese vowels by using 10 five-item semantic differential scales. The results reveal that the physical characteristics of the facial expressions (mouth shapes) induced specific evaluations. For example, the mouth shape made to voice the vowel “a” was the one with the biggest, widest, and highest facial components compared to other mouth shapes, and people perceived words containing that vowel sound as bigger. The mouth shapes used to pronounce the vowel “i” were perceived as more likable than the other four vowels. These findings indicate that the mouth shapes producing vowels imply specific meanings. Our study provides clues about the meaning of verbal sounds and what the facial expressions in communication represent to the perceiver.
Simple and Facile Fabrication of Anion-Vacancy-Induced MoO3−X Catalysts for Enhanced Hydrogen Evolution Activity
Authors: Jo Seunghwan , Lee Young-Woo , Hong John , Sohn Jung Inn
Published: October 2020

Advanced catalysts for clean hydrogen generation and storage offer an attractive possibility for developing a sustainable and ecofriendly future energy system. Transition metal oxides (TMO) are appealing candidates to be largely considered as electrode catalysts. However, for practical applications, there are still challenges—the intrinsic catalytic properties of TMOs should be further improved and TMOs should be synthesized by practical routes for cost-effective and scalable production of catalysts. Therefore, finding promising ways to fabricate highly active TMOs with outstanding electrochemical hydrogen evolution performance is required. Here, we present a direct and facile synthetic approach to successfully provide highly efficient MoO3−X catalysts with electrochemically active oxygen vacancies through a one-step thermal activation process on a Mo metal mesh. Variations in the oxidation states of molybdenum oxides can significantly increase the active sites of the catalysts and improve the electrochemical activity, making these oxide compounds suitable for hydrogen evolution reaction (HER). Compared to the bare Mo mesh and fully oxidized Mo (MoO3) electrodes, the fabricated MoO3−X electrode exhibits better electrochemical performance in terms of overpotentials and Tafel slope, as well as the electrochemical 1000 cycling stability, confirming the improved HER performance of MoO3−X. This provides new insight into the simple procedure suitable for the large-production supply.
Interesterification of Egg-Yolk Phosphatidylcholine with p-Methoxycinnamic Acid Catalyzed by Immobilized Lipase B from Candida Antarctica
Authors: Rychlicka Magdalena , Gliszczyńska Anna
Published: October 2020

The p-methoxycinnamic acid (p-MCA) is one of the most popular phenylpropanoids, the beneficial impact of which on the human health is well documented in the literature. This compound has shown many valuable activities including anticancer, antidiabetic, and neuro- and hepatoprotective. However, its practical application is limited by its low bioavailability resulting from rapid metabolism in the human body. The latest strategy, aimed at overcoming these limitations, is based on the production of more stability in systemic circulation bioconjugates with phospholipids. Therefore, the aim of this research was to develop the biotechnological method for the synthesis of phospholipid derivatives of p-methoxycinnamic acid, which can play a role of new nutraceuticals. We developed and optimized enzymatic interesterification of phosphatidylcholine (PC) with ethyl p-methoxycinnamate (Ep-MCA). Novozym 435 and a binary solvent system of toluene/chloroform 9:1 (v/v) were found to be the effective biocatalyst and reaction medium for the synthesis of structured p-MCA phospholipids, respectively. The effects of the other reaction parameters, such as substrate molar ratio, enzyme dosage, and reaction time, on the degree of incorporation of p-MCA into PC were evaluated by use of an experimental factorial design method. The results showed that substrate molar ratio and biocatalyst load have significant effects on the synthesis of p-methoxycinnamoylated phospholipids. The optimum conditions were: Reaction time of three days, 30% (w/w) of Novozym 435, and 1/10 substrate molar ratio PC/Ep-MCA. Under these parameters, p-methoxycinnamoylated lysophosphatidylcholine (p-MCA-LPC) and p-methoxycinnamoylated phosphatidylcholine (p-MCA-PC) were obtained in isolated yields of 32% and 3% (w/w), respectively.
Service Behavior of Nitride Layers of Steels for Military Applications
Authors: Prochazka Jiri , Pokorny Zdenek , Dobrocky David
Published: October 2020

Steels which are utilized in the manufacturing of specific parts of military technology such as crankshafts of engines in heavy-duty vehicles or barrels of guns must be subsequently modified by heat treatment according to the requirements of customers. Despite the hard surface of martensitic structure obtained by hardening process, steels have a low wear resistance and high values of coefficient of friction. To improve these parameters and due to the fact that many of steels which are utilized for manufacturing of mentioned parts are also categorized as Nitralloy steels, in this paper, the improvement in these properties of chosen steels by the application of plasma nitriding has been studied. The steel equivalent 17Ni4CrMo (i.e., CSN 41 6720) and equivalent 42CrMo4 (i.e., CSN 41 5142) were chosen for the study. The chemical composition of chosen steels was verified by optical emission spectrometry. The microstructure and the diffusion layer were observed by optical microscopy due to the evaluation of layer parameters important for the lifetime. ZWICK ZHU 2.5 was used for a measurement of the universal hardness of the surface and values of graphs of microhardness were obtained by the device LM 247AT LECO from a cross-section of samples. The coefficient of friction was determined by Bruker CERT-UMT-3 with a ball-on-disc method. The parameters of wear paths were obtained by Talysurf CLI 1000. After the application of plasma nitriding technology, the hardness of both steels was rapidly increased in comparison with non-nitrided samples. According to the comparison of coefficients of friction with respect to the parameters of the measurement, the coefficient of friction of nitrided samples decreases with increasing temperature, which is essential knowledge for the weapon industry, especially the construction of bore barrel.
A Facile Fabrication Route of Poly(Ethylene Glycol Phenyl Ether Acrylate) Photopolymers with Efficient Optical Response for Holographic Storage
Authors: Lee Fang-Yong , Wang Xin-Jin , Su Wei-Hung , Hsu Tzu-Chien
Published: October 2020

A series of photopolymers based on ethylene glycol phenyl ethyl arylate (EGPEA) monomers and poly(methyl methacrylate) (PMMA) matrix with varying initiator concentrations and sample thicknesses have been synthesized and their optical performance characterized in this study. The advantages of lowering the initiator concentration, including a rather short initiation time within a few seconds; a sharp rising optical response; and a stable saturated diffraction efficiency are demonstrated. The variation in the diffraction efficiency and response time with the exposure energy under various sample thickness and initiator concentrations is examined; a diffraction efficiency as high as 80% and a relatively short response time of 12–39 s are attainable. The dependence of the normalized optical parameter “sensitivity” on the exposure time is depicted, and the peak value of S ranges vastly from about 0.2 to 1.2 × 104 cm/J within a period of 15 s or so, with a maximum value of nearly 1.2 × 104. Favorable evidence of low initiator concentration can further be found when the dependence of the saturated diffraction efficiency with the exposure energy is examined. The data from this study using a low initiator concentration cover a range of exposure energy from 100 to 800 mJ/cm2 and a saturated diffraction efficiency from about 15% to 80%. The successful image reconstruction of 6-membered-ring metal nuts on a hologram based on this EGPEA/PMMA photopolymer system using a reflective holographic recording setup is demonstrated to verify its applicability to holographic storage.
Understory Species Identity Rather than Species Richness Influences Fine Root Decomposition in a Temperate Plantation
Authors: Khlifa Rim , Angers Denis A. , Munson Alison D.
Published: October 2020

Different silvicultural treatments that are applied at plantation establishment may drive different vegetation succession pathways. These divergent vegetation types subsequently feed back to influence soil carbon and nitrogen cycles. One potential mechanism of feedback is through litter decomposition, and in particular fine root decomposition (FRD; <2 mm roots). In the present study we investigated how blade scarification, fertilization, and vegetation control influenced over- and understory vegetation 27 years after plantation, and whether these different vegetation communities affected FRD. In a design using factorial combinations of the three treatments at the Petawawa Research Forest (Laurentian Hills, ON, Canada), we conducted an in situ FRD experiment, with fine roots from the entire vegetation community (both over- and understory) of each plot. The different silvicultural treatments affected overstory basal area, understory species richness and FRD. No correlation was noted between understory species richness and FRD. Instead, we found that understory vegetation (especially fern and herb) cover best explained FRD. We conclude that silvicultural treatments affect FRD through subsequent vegetation succession and that this effect is more likely due to species-specific effects inducing a favorable soil environment than to a higher species richness per se.
Eustatic, Climatic and Tectonic Controls on the Evolution of a Middle to Late Holocene Coastal Dune System in Shimokita, Northeast Japan
Authors: Minoura Koji , Nakamura Norihiro
Published: October 2020

The Pacific coast of the Shimokita Peninsula, Northeast Japan, is occupied by one of the larger dune complexes in Japan. This coastal aeolian dune complex developed during the Holocene in a monsoon-influenced temperate climatic belt. The stratigraphic and sedimentological characteristics of outcrops, exposures and cores indicate that four generation of aeolian dunes are presented. These dunes developed during eustatic regression following the post-glacial sea-level highstand. Seaward shoreline movement, combined with strong winds from the Pacific Ocean, enhanced aeolian grain transport on the beach, resulting in the onset of dune growth and the consequent shrinkage of the coastal forest. Northeast Japan is located in a transitional zone affected largely by monsoonal circulation from Siberia and Southeast Asia. Thus, the regional climate is responsible for atmospheric changes on a hemispheric scale. Intensified monsoons contributed to flooding produced by rains and snow-melt. Steep increases in annual precipitation at 7200–6300, 4700–3600, 3050–2500, 1850–1100, and 550–200 calendar years before present (cal. yr. BP) increased the amount of surface erosion, causing a large volume of sediment discharge toward the coast. Shimokita has experienced frequent earthquakes and tsunamis, which have reduced dune landform relief by sediment displacement.
Effects of Hyperbaric Oxygen Therapy on Inflammation, Oxidative/Antioxidant Balance, and Muscle Damage after Acute Exercise in Normobaric, Normoxic and Hypobaric, Hypoxic Environments: A Pilot Study
Authors: Woo Jinhee , Min Jae-Hee , Lee Yul-Hyo , Roh Hee-Tae
Published: October 2020

The purpose of this study was to investigate the effects of hyperbaric oxygen therapy (HBOT) on inflammation, the oxidative/antioxidant balance, and muscle damage after acute exercise in normobaric, normoxic (NN) and hypobaric, hypoxic (HH) environments. Eighteen healthy males were selected and randomly assigned to three groups: exercise in NN conditions (NN group, n = 6), HBOT treatment after exercise in NN conditions (HNN group, n = 6), and HBOT treatment after exercise in HH conditions (HHH group, n = 6). All subjects performed treadmill running for 60 min at 75–80% maximum heart rate (HRmax) exercise intensity under each condition. The HBOT treatments consisted of breathing 100% oxygen at 2.5 atmosphere absolute (ATA) for 60 min. Blood samples were collected before exercise (BE), after exercise (AE), and after HBOT (AH) to examine inflammation (fibrinogen, interleukin-6 [IL-6], and tumor necrosis factor-α (TNF-α)), the oxidative/antioxidant balance (derivatives of reactive oxygen metabolites (d-ROMs) and the biological antioxidant potential (BAP)), and muscle damage (creatine kinase (CK) and lactate dehydrogenase (LDH)). Plasma fibrinogen, serum IL-6, CK, and LDH levels were significantly increased AE compared to BE in all groups (p < 0.05). Plasma fibrinogen levels were significantly decreased AH compared to AE in all groups (p < 0.05), and the HNN group had a significantly lower AH compared to BE (p < 0.05). Serum IL-6 levels were significantly decreased AH compared to AE in the HNN and HHH groups (p < 0.05). Serum CK levels were significantly decreased AH compared to AE in the HHH group (p < 0.05). Serum LDH levels were significantly decreased AH compared to AE in the HNN and HHH groups (p < 0.05), and the NN and HNN groups had significantly higher AH serum LDH levels compared to BE (p < 0.05). These results suggest that acute exercise in both the NN and HH environments could induce temporary inflammatory responses and muscle damage, whereas HBOT treatment may be effective in alleviating exercise-induced inflammatory responses and muscle damage.
Sexual and Mental Health Inequalities across Gender Identity and Sex-Assigned-at-Birth among Men-Who-Have-Sex-with-Men in Europe: Findings from EMIS-2017
Authors: Hickson Ford , Appenroth Max , Koppe Uwe , Schmidt Axel J. , Reid David , Weatherburn Peter
Published: October 2020

Some men who have sex with men (MSM) were assigned female at birth (AFB) and/or identify as trans men. Little is known about how these men differ from other MSM. We compared sexual and mental health indicators from the European MSM Internet Survey (EMIS-2017), comparing men AFB and/or currently identifying as trans men with those assigned male at birth (AMB) who identified as men. EMIS-2017 was an opportunistic 33-language online sexual health survey for MSM recruiting throughout Europe. We used regression models adjusting for age, country of residence and employment status to examine differences across groups. An analytic sample of 125,720 men living in 45 countries was used, of which 674 (0.5%) were AFB and 871 (0.7%) identified as trans men. The two sub-groups were not coterminous, forming three minority groups: AFB men, AFB trans men and AMB trans men. Minority groups were younger and more likely unemployed. Anxiety, depression, alcohol dependence and sexual unhappiness were more prevalent in sex/gender minority men. Conversely HIV and STI diagnoses were less common. AMB trans men were most likely to have sexual risk behavior with steady partners and to have unmet health promotion needs, and were least likely to be reached by interventions. Sex assigned at birth and trans identification were associated with different sexual and mental health needs. To facilitate service planning and to foster inclusion, sex-assigned-at-birth and current gender identity should be routinely collected in health surveys.
Influence of Food and Beverage Companies on Retailer Marketing Strategies and Consumer Behavior
Authors: Hecht Amelie A. , Perez Crystal L. , Polascek Michele , Thorndike Anne N. , Franckle Rebecca L. , Moran Alyssa J.
Published: October 2020

The retail food environment plays an important role in shaping dietary habits that contribute to obesity and other chronic diseases. Food and beverage manufacturers use trade promotion—incentives paid to retailers—to influence how products are placed, priced, and promoted in stores. This review aims to: (1) catalogue trade promotion practices that manufacturers use to influence retailer marketing strategies, and (2) describe how these retailer marketing strategies affect consumer purchasing behavior and attitudes. Researchers searched five databases, Academic Search Ultimate, Business Source Ultimate, PsycINFO, PubMed, and Web of Science, to identify literature from industry and academic sources published in English through November 2019. Twenty articles describing manufacturer trade promotion practices were synthesized and provided insight into four types of trade promotion practices: category management, slotting allowances, price discounts, and cooperative advertising. Fifty-four articles describing the impact of retailer marketing on consumers were synthesized and graded for quality of evidence. While comparison across studies is challenging, findings suggest that retailer marketing strategies, such as price promotions and prominent placement, lead to increased sales. Results can guide efforts by policymakers, public health practitioners, and food retailers to design retail environments that improve healthy eating while maintaining retailer financial interests. Additional research should measure the impact of retailer marketing strategies on consumer diet quality and retailer outcomes (e.g., return-on-investment).
Environmental Epigenetics of Diesel Particulate Matter Toxicogenomics
Authors: Bilinovich Stephanie M. , Lewis Kristy , Thompson Barbara L. , Prokop Jeremy W. , Campbell Daniel B.
Published: October 2020

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disruptions in social communication and behavioral flexibility. Both genetic and environmental factors contribute to ASD risk. Epidemiologic studies indicate that roadway vehicle exhaust and in utero exposure to diesel particulate matter (DPM) are associated with ASD. Using the Comparative Toxicogenomics Database (CTD), we identified genes connected to DPM exposure and ASD, extracted the known enhancers/promoters of the identified genes, and integrated this with Assay for Transposase Accessible Chromatin (ATAC-seq) data from DPM-exposed human neural progenitor cells. Enhancer/promoter elements with significantly different chromosome accessibility revealed enriched DNA sequence motifs with transcription factor binding sites for EGR1. Variant extraction for linkage disequilibrium blocks of these regions followed by analysis through Genome Wide Association Studies (GWAS) revealed multiple neurological trait associations including exploratory eye movement and brain volume measurement. This approach highlights the effects of pollution on the regulatory regions of genes implicated in ASD by genetic studies, indicating convergence of genetic and environmental factors on molecular networks that contribute to ASD. Integration of publicly available data from the CTD, cell culture exposure studies, and phenotypic genetics synergize extensive evidence of chemical exposures on gene regulation for altered brain development.
Intervention Response to the Trauma-Exposed, Justice-Involved Female Youth: A Narrative Review of Effectiveness in Reducing Recidivism
Authors: Thomann Ashley , Keyes Latocia , Ryan Amanda , Graaf Genevieve
Published: October 2020

This study aims to examine current research about trauma-exposed, justice-involved (TEJI) female youth, and evaluate the current literature regarding the effectiveness of gender-specific interventions aimed at reducing their recidivism. Preferred reporting items for systematic reviews and meta-analyses (PRISMA) methodology was utilized to examine quantitative and qualitative literature, published from 2000 through March 2020, about interventions for female justice-involved youth with trauma exposure. Analysis of selected studies utilized an integrated framework based on Andrew’s Risk-Need-Responsivity (RNR) model and Lipsey’s factors of effectiveness, which reviewed studies showing the relationship between female justice-involved youth with mental health symptomologies and trauma. The findings show that effective intervention for this population targets the youth’s negative internal mechanisms related to trauma-subsequent psychosocial problems. These studies suggest that trauma-sensitive modalities have the potential to mitigate the further risk of problematic external behaviors. All studies had limited sample sizes, low follow-up rates, and unknown long-term outcomes. Future research should explore dimensions of sustainability and achieving stability in relation to intervention setting. Selecting the proper venue and facilitator for quality implementation and stability of setting is critical in delivering effective therapies. Modifications in public expectations of juvenile justice policy and practice, from disciplinary to therapeutic approaches, is needed.
The Influence of COVID-19 Isolation on Physical Activity Habits and Its Relationship with Convergence Insufficiency
Authors: Mon-López Daniel , Bernardez-Vilaboa Ricardo , Fernandez-Balbuena Antonio Alvarez , Sillero-Quintana Manuel
Published: October 2020

The purpose of this work is to evaluate the effects of confinement due to COVID-19 isolation on visual function, considering insufficient convergence as one of the possible effects of living the whole day in a reduced space. We pass a Convergence Insufficiency Symptom Survey (CISS) among 235 people to detect their habits before and after 25 confinement days. The data collection protocol consisted on a Google forms questionnaire included two parts: the first with current data (isolation period) and a second with pre-isolation period data. Differences between the pre-isolation and isolation period were calculated using the related paired T-tests. When statistically significant differences were found, the effect size was estimated using the Cohen’s d index (d). The reduction in physical activity levels during confinement were related to the increase in total number of minutes of screen consumption from 433.49 min to 623.97 min per day (d = 0.67; 44.01%). The CISS scores were increased by more than 43% during confinement. The increase in convergence insufficiency was 100% after the studied isolation period of 25 days. The 92.19% increase in television use during 25 days of confinement is not responsible for the increase in convergence insufficiency. However, due to the increase in the use of PCs in this period, there is a notable increase in convergence insufficiency. Therefore, we can conclude that not all increases in tasks with electronic devices are responsible for the increase in convergence insufficiency.
Association between Urinary Triclosan and Serum Testosterone Levels in U.S. Adult Males from NHANES, 2011–2012
Authors: Yan Judy , Joseph Michael A. , Reynolds Simone A. , Geer Laura A.
Published: October 2020

Triclosan was introduced into the market in the 1970s and has since been used as an antimicrobial agent in a diverse array of consumer and personal care products. Although it has been widely used over a number of years, there is growing concern and debate over its safety and efficacy and its potential as an endocrine disruptor. Although prior animal toxicology studies have shown an association between triclosan and decreased testosterone levels, human studies have been limited, particularly for adult men. Using the National Health and Nutrition Examination Survey data (NHANES, 2011–2012), we examined the association of urinary triclosan on testosterone levels in adult men 18–65 years of age. Multivariable linear regression analysis failed to show an association between triclosan and serum testosterone (β = 0.0003, p = 0.98, 95% CI = −0.024, 0.025). The results suggest there is no association or that triclosan concentrations are too low to cause a significant impact on testosterone levels. Additionally, longitudinal studies would provide a more comprehensive understanding of the direction of change and magnitude of causal relationships over time.
Can Childcare Work Be Designed to Promote High Intensity Physical Activity for Improved Fitness and Health? A Proof of Concept Study of the Goldilocks Principle
Authors: Lerche Anders Fritz , Vilhelmsen Maja , Schmidt Kathrine Greby , Kildedal Rasmus , Launbo Natja , Munch Pernille Kold , Lidegaard Mark , Jacobsen Sandra Schade , Rasmussen Charlotte Lund , Mathiassen Svend Erik , Straker Leon , Holtermann Andreas
Published: October 2020

Childcare workers are reported to have high variation in physical activity during work hours, but also to sit for about half of the workday and have almost no high intensity physical activity (HIPA). No study has investigated if their work can be re-designed to introduce HIPA, thus promoting fitness and health according to the Goldilocks principle. This study investigated the feasibility of designing pedagogical games (‘Goldilocks-games’) intended to lead to more HIPA. Heart rate was measured in nineteen childcare workers during Goldilocks-games, and compared to measurements during a regular workday. Worker perceptions of feasibility, and researcher observations of contextual factors were also collected. The Goldilocks-games (33 min) elicited significantly more HIPA (18/33 min) compared to the most active period of equal length on a regular workday (0.5/33 min). Seventy-four-percent of the childcare workers reported that it was feasible to integrate the Goldilocks-games pedagogically, and seventy-two-percent could see themselves using them. Thus, we found it possible to re-design a work task in childcare according to the Goldilocks principle so that it leads to substantial time with HIPA. The sustainability of Goldilocks-games in childcare, and their effectiveness in improving fitness and health among childcare workers, needs to be tested in further studies.
Do Long-Run Disasters Promote Human Capital in China? —The Impact of 500 Years of Natural Disasters on County-Level Human-Capital Accumulation
Authors: Zhang Zhidi , Ruan Jianqing
Published: October 2020

Is there a relationship between the frequency of regional natural disasters and long-term human-capital accumulation? This article investigates the long-run causality between natural calamities and human-capital accumulation with macro and micro data. Empirical cross-county analysis demonstrates that higher frequencies of natural calamities are correlated with higher rates of human-capital accumulation. Specifically, on the basis of empirical data of the fifth census in 2000 and China’s Labor-Force Dynamics Survey in 2012, this paper exploits the two databases to infer that the high disaster frequency in the years of 1500–2000 was likely to increase regional human-capital accumulation on district level. High natural-calamity frequency reduces the expected rate of returning to physical capital, which also serves to increase human-capital. Thus, experiencing with natural disasters would influence human’s preference to human-capital investment instead of physical capital.
Radon Exposure and Neurodegenerative Disease
Authors: Gómez-Anca Silvia , Barros-Dios Juan Miguel
Published: October 2020

Background: To carry out a systematic review of scientific literature about the association between radon exposure and neurodegenerative diseases. Methods: We performed a bibliographic search in the following databases: Pub med (Medline), Cochrane, BioMed Central and Web of Science. We collected the data by following a predetermined search strategy in which several terms werecombined. After an initial search, 77 articles were obtained.10 of which fulfilled the inclusion criteria. Five of these 10 studies were related to multiple sclerosis (MS), 2 were about motor neuron diseases (MND), in particular amyotrophic lateral sclerosis (ALS) and 3 were related to both Alzheimer’s disease (AD) and Parkinson’s disease (PD). Results: The majority of the included articles, suggested a possible association between radon exposure and a subsequent development of neurodegenerative diseases. Some of the studies that obtained statistically significant resultsrevealed a possible association between radon exposure and an increase in MS prevalence. Furthermore, it was also suggested that radon exposure increases MND and AD mortality. Regarding AD and PD, it was observed that certainde cay products of radon-222 (222Rn), specifically polonium-210 (210Po) and bismuth-210 (210Bi), present a characteristic distributionpattern within the brain anatomy. However, the study with the highest scientific evidence included in this review, which investigated a possible association between the concentration of residential radon gas and the MS incidence, revealed no significant results. Conclusions: It cannot be concluded, although it is observed, that there is a possible causal association between radon exposure and neurodegenerative diseases. Most of the available studies are ecological so, studies of higher statistical evidence are needed to establish a causal relationship. Further research is needed on this topic.
Association between Anemia and Stroke in Females: A Nationwide, Population-Based Cohort Study in Taiwan
Authors: Sui Yuan , Hong Chien-Tai , Chien Li-Nien , Liu Hung-Yi , Chiou Hung-Yi , Hsieh Yi-Chen
Published: October 2020

Optimal stroke prevention strategies for women should take into account specific sex-related stroke risk factors. Anemia is a common medical condition in females, particularly in women of reproductive age. This study investigated whether anemia is an independent risk factor for stroke in females in a population-based cohort study. We investigated newly diagnosed anemic female patients with no history of central nervous system disease, psychiatric disorders, traumatic brain injury, major operations or hemorrhagic diseases identified from the Taiwan National Health Insurance Research Database. Non-anemic matched controls (1:1) were selected based on a propensity score estimated using a logistic regression model that included demographic characteristics and comorbidities. A competing risk analysis was applied to estimate the stroke risk in anemic patients compared to that of their matched controls. In our study, the adjusted sub-distribution hazard ratios (aSHRs) of overall, hemorrhagic and ischemic stroke in anemic female patients aged <50 years were 1.35 (95% confidence interval (CI): 1.19–1.52, p < 0.001), 1.31 (95% CI, 1.09-1.56, p < 0.003), and 1.35 (95% CI, 1.15–1.58, p < 0.001), respectively, compared to non-anemic female controls. However, a positive association between anemia and stroke was not found for those aged ≥50 years. Similar results were observed when the follow-up age was limited to 50 years to reduce the potential effects of menopause on stroke. In conclusion, the present population-based cohort study found that anemia is a potential risk factor for overall, hemorrhagic and ischemic stroke in females of reproductive age.
COVID-19 Pandemic: Knowledge and Attitudes in Public Markets in the Former Katanga Province of the Democratic Republic of Congo
Authors: Carsi Kuhangana Trésor , Kamanda Mbayo Caleb , Pyana Kitenge Joseph , Kazadi Ngoy Arlène , Muta Musambo Taty , Musa Obadia Paul , Katoto Patrick D.M.C. , Banza Lubaba Nkulu Célestin , Nemery Benoit
Published: October 2020

Background. Public markets were exempted from the restrictive regulations instituted to limit the rapid spread of the COVID-19 pandemic in the Democratic Republic of the Congo (DRC). In the early stage of the pandemic, we assessed people’s knowledge, attitudes, and behavior on public markets towards COVID-19. Methods. We conducted a cross-sectional study from 16 to 29 April 2020 among sellers and customers frequenting the food sections of ten public markets in three large cities (Kolwezi, Likasi, and Lubumbashi) and one small town (Lwambo) of the former Katanga province. We administered a questionnaire on knowledge (about clinical characteristics, transmission and prevention) and on attitudes in relation to COVID-19. We also observed prevailing practices (hand-washing and mask-wearing). Results: Of the 347 included participants (83% women, 83% sellers), most had low socioeconomic status and a low level of education. Only 30% of participants had correct knowledge of COVID-19. The majority of the respondents (88%) showed no confidence in the government’s ability to manage the upcoming pandemic crisis. Nearly all respondents (98%) were concerned about the associated increase in food insecurity. Preventive practices were rarely in place. Conclusion: For an effective implementation of measures to prevent the spread of COVID-19 in Africa, appropriate health education programs to improve knowledge and attitudes are warranted among the population frequenting public markets.
Occupational Physicians’ Perspectives on Determinants of Employee Participation in a Randomized Controlled Musculoskeletal Health Promotion Measure: A Qualitative Study
Authors: Schubin Kristina , Schlomann Lara , Lindert Lara , Pfaff Holger , Choi Kyung-Eun
Published: October 2020

Occupational physicians (OPs) are key figures for advising employees and employers about prevention and health at the workplace. However, knowledge of their views on participation in health promotion measures is sparse. This qualitative study aims to explore occupational physicians’ experiences with employee participation in a randomized controlled workplace measure for musculoskeletal disorders (MSDs) in Germany. We conducted eight semi-structured telephone interviews with occupational physicians. Interviews were transcribed verbatim and analyzed using a combination of conventional and directed content analysis. Findings were mapped based on Andersen’s behavioral model of health services use, resulting in four categories and 10 subcategories. (a) Contextual factors of the measure comprised impacts of the healthcare system and company environment, (b) individual factors of measure participation comprised demographic, social, belief, and MSD need characteristics, (c) health behavior during the measure included OPs’ communication, employees’ personal practices and measure participation, and (d) outcomes of participation included health status, satisfaction, and dissatisfaction with the measure. Findings imply occupational physicians’ and employees’ views should be investigated on a broader scale. Researchers should use present statements for the development of intervention studies, while political and managerial authorities can improve organizational conditions of prevention based on these findings.
German Dentists’ Preferences for the Treatment of Apical Periodontitis: A Cross-Sectional Survey
Authors: Conrad Jonas , Retelsdorf Jan , Attia Sameh , Dörfer Christof , Mekhemar Mohamed
Published: October 2020

Currently, there is no standard treatment protocol for apical periodontitis (AP). Thus, restorable teeth might get extracted and replaced prosthetically. This study evaluated German dentists’ preferred AP treatment decisions and the influencing factors for selecting tooth retention by initial/repeated surgical/non-surgical root-canal treatment (RCT) or extraction with/without prosthetic replacement. Through an online-survey, participants (n = 260) rated different treatment options for four case scenarios with AP in anterior/posterior teeth without/with previous RCT. Statistical analysis included the Friedman test for intra-case comparisons and Chi-squared test for factor-associations (p ≤ 0.05). Tooth retention using initial/repeated RCT was ranked first in all scenarios and rated as (very) appropriate by most participants, while implant-supported crowns (ISC) and apicoectomy had the second ratings. ISC were preferred more on posterior teeth or previous root-canal-treated teeth. Rating levels of treatment options displayed significant differences for all case scenarios. Posterior tooth retention by RCT demonstrated a significant association with work experience. Tooth retention with previous RCT displayed a significant correlation with dentists’ privately insured patients. Most dentists preferred tooth preserving with initial/repeated RCT, while others selected non-evidence-based choices. This reflects a lack of consensus of AP treatment decisions in Germany. Fixed treatment guidelines and further evaluation of treatment–decision-correlated factors are recommended for correct treatment planning.
Continuity and Overlap of Roles in Victims and Aggressors of Bullying and Cyberbullying in Adolescence: A Systematic Review
Authors: Estévez Estefanía , Cañas Elizabeth , Estévez Jesús F. , Povedano Amapola
Published: October 2020

The objective of this study was to conduct a systematic review of research focused on analyzing the overlap and continuity of the roles in victims and aggressors of bullying and cyberbullying, as well as the exchange of roles in both harassment dynamics in adolescents. Searches in the main electronic databases for studies published in the last 20 years identified 19 studies that fulfilled inclusion criteria. The findings of the studies analyzed were not homogeneous, however, the main conclusion of all of them, to a greater or lesser extent, was that there is a component of continuity or superposition in the roles of both forms of bullying. Some studies also found an exchange of roles, especially in the case of victims and cybervictims who decide to reprimand their aggressors in an online context, becoming in cyberaggressors too. It is necessary to continue investigating the coexistence of bullying and cyberbullying and its exchange in certain contexts and people, as well as whether they are part of the same phenomenon with a certain continuity, or if cyberbullying is another expression of traditional bullying. Future intervention programs focusing on traditional school bullying could also evaluate their impact in situations of cyberbullying among peers.
The Hospice as a Learning Environment: A Follow-Up Study with a Palliative Care Team
Authors: Testoni Ines , Sblano Vito Fabio , Palazzo Lorenza , Pompele Sara , Wieser Michael Alexander
Published: October 2020

In Western society, the topic of death has been removed from everyday life and replaced with medical language. Such censorship does not reduce individuals’ fear of death, but rather limits their ability to elaborate their experiences of death, thus generating negative effects. The objective of this follow-up qualitative study was to detect how and if death education can help to improve individuals’ relationship with death and enhance care environments like hospices. Semi-structured interviews were conducted with palliative care professionals and teachers who had taken part in a death education initiative three years earlier. The results confirmed the initiative’s positive effect on both palliative care professionals and teachers. The participants reported that the education initiative helped them to positively modify their perspective on death, end-of-life care, and their own relationship to life, as well as their perception of community attitudes towards the hospice, which seemed to become less discriminatory. This study confirmed that school education initiatives can usefully create continuity between hospices and local communities. This project provided an educational space wherein it was possible for participants to elaborate their experiences in relation to death and to re-evaluate and appreciate hospices.