bluuebunny/crossref_metadata_2025 huggingface dataset:
DRY POWDER FORMULATION FROM PHYSALIS PERUVIANA L. FRUITS EXTRACT WITH ANTIDIABETIC ACTIVITY FORMULATED VIA CO-SPRAY DRYING
Authors: BERNAL CARLOS A. , RAMOS FREDDY A. , BAENA YOLIMA
Published: May 2019

Objective: To establish the drying conditions of an extract of fruits of Physalis peruviana using spray drying (SD) technique by applying a statistical experimental design (SED), to obtain powders for direct compression, retaining the antidiabetic activity.

Methods: A 2[6-2] fractional factorial SED was used to get a suitable SD operating conditions to produce powder extract of P. peruviana with high process yield, acceptable moisture content, good flowability, low hygroscopicity and satisfactory morphological and particle size. Operating variables studied were air inlet temperature, atomization air flow rate, feed-rate pump, aspiration rate, extract concentration and coadjuvant proportion. P. peruviana powder obtained under the operating conditions selected was evaluated by X-ray powder diffraction (XRPD), differential scanning calorimetry (DSC) and by in vitro α-amylase inhibition assay, to prove that the antidiabetic activity was remained after the SD.

Results: Injection temperature (120 °C), atomization air flow rate (600 l/h), pump setting (5 %), aspirator setting (100 %), extract concentration (7.5 % p/p) and extract: coadjuvant ratio (1:0.75), were the operational conditions selected. Dry extract showed an amorphous state by XRPD and a probable protective effect of coadjutant on the extract, characterized by DSC and the antidiabetic in vitro assay. Antidiabetic activity of the extract remained after its transformation to a solid state by SD in the chosen conditions.

Conclusion: The results suggest that coprocessed extract could be used for the production of compressed solids or employed as an intermediate herbal product for the treatment of diabetes.
ROLE OF HYDROPHILIC SURFACTANTS IN THE EMULSIFICATION MECHANISTICS OF TYPE III SELF-MICRO-EMULSIFYING DRUG DELIVERY SYSTEMS (SMEDDS)
Authors: HASAN NASER M. Y.
Published: May 2019

Objective: Evaluation of the self-emulsifying behaviour of type III lipid systems comprising mixed medium chain glycerides (Miglyol 812-Imwitor 988) and wide range of hydrophilic surfactants in an attempt to identify self-emulsifying microemulsion formulations, prevaricate the crystallization tendency of Cremophor RH40 in the pre-microemulsion concentrate, to shed some light on the mechanistic behavior of these systems after aqueous dispersion.

Methods: Non-ionic surfactants with HLB in the range 14 to 16.5 are investigated amongst these are; Cremophor RH40, Cremophor EL, Crillet 4 (polysorbate 80), Crillet 1 (polysorbate 20) and Tagat O2. Optimum oil blends of Miglyol 812-Imwitor 988 and various non-ionic surfactant systems were verified using self-emulsification performance studies, oil droplet diameter measurements and dynamic equilibrium phase studies.

Results: Oil blends of Miglyol 812 as an oil and Imwitor 988 as a cosurfactant were optimized for microemulsion systems at ratios of 1:1 in the case of Cremophor RH40 or EL, and at 2:3 in the case of Crillet 4 or Tagat O2. In order to obtain small droplet size and fast dispersion rate for type III lipid systems, hydrophilic surfactants with HLB values between 13 and 15 were found to be the optimum.

Conclusion: Spontaneous micro-emulsification in type III lipid system was attributed to the “diffusion and stranding” theory. Yet, the formation of liquid crystalline phases as intermediate phases during dilution of the oil formulation with water appears to be quintessential for the mechanistics of emulsification regardless type of lipid class system.
FORMULATION AND EVALUATION OF GRAPHENE GRAFTED CHITOSAN/POLYANILINE NANOCOMPOSITES FOR CONTROLLED RELEASE OF ANTICANCER DRUG DOXORUBICIN
Authors: MOHANTY SUCHISMITA , SARANGI SUBRATA , ROY GOURI SANKAR
Published: May 2019

Objective: The purpose of the present study was to functionalized graphene (f-GE) grafted chitosan (CS)/Polyaniline (PANI) with Montmorillonite (MMT) was different feed ratio known as f-GE-g-(CS/MMT-PANI).

Methods: The prepared f-GE-g-(CS/MMT-PANI) was formulated using the solvent casting method. The prepared nanocomposites were characterized by X-Ray Diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), Thermogravimetric analysis (TGA), thermogravimetric (DTG) and swelling in stimulated in the different biological fluid. The model drug Doxorubicin (DOX) was used for controlled drug delivery purpose.

Results: From FTIR result was clearly demonstrated that the model drug DOX did not change in any molecular level at f-GE-(CS/MMT-PANI) (i.e. at<10 nm scale). Additionally, in DSC result, DOX was interacted with nanocomposites at scale>100 nm level. With CS as the carrier, 60% of the drug was released in SIF for the initial 120 min and this increased to 80–82% with f-GE-g-CS/MMT/PANI matrix. But in SGF, CS as the carrier, 46% of the drug was released in 140 min and this increased to 78% with f-GE-g-CS/MMT/PANI. In vitro drug release system was carried out by Korsmeyer Peppas’s power law. DOX and other drugs like Doxorubicin (DOX) was presented an exceptional higher drug result in different pH medium.

Conclusion: It was observed that CS/MMT was decreasing less drug release rate compared to f-GE-g-(CS/MMT-PANI). So that it can be clearly understood that f-GE-g-(CS/MMT-PANI) grafted nanocomposites have enhanced drug release activity in different pH medium.
ENERGY SAVINGS ON CURCUMINE DERIVATIVE GAMAVUTON-0 SYNTHESIS USING MICROWAVE IRRADIATION
Authors: Harimurti Sabtanti , Nugroho Winny Setyo , Pramono Ardi
Published: May 2019

Objective: The aim of this study was to develop a more effective and environmentally friendly synthesis method for anti-cancer curcumine derivatives, namely 1,5-bis (4’-hydroxy-3’-metoxyfenyl)-1,4-pentadiene-3-one or gamavuton-0.

Methods: The experiment was conducted using two different energy sources, i.e. conventional heating and microwave irradiation. Vanillin and acetone were used as starting materials, and hydrochloric acid as the catalyst. During synthesis, variations in the synthesis period were carried out to study the effect of time on the gamavuton-0 produced. Based on experimental data, energy consumption between conventional method and microwave were evaluated.

Results: Evaluation of energy consumption was calculated based on experimental data. It was found that energy consumption for production using microwave irradiation was reduced to 0.0014 kWh/gram of crude gamavuton-0 products from 0.19 KWh/gram of crude gamavuton-0 product using conventional heating.

Conclusion: Based on calculations from experimental data, microwave irradiation during the synthesis of gamavuton-0 significantly saves energy consumption for synthesis.
SIMULTANEOUS IDENTIFICATION AND QUANTIFICATION OF HYDROQUINONE, TRETINOIN AND BETAMETHASONE IN COSMETIC PRODUCTS BY ISOCRATIC REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
Authors: Maggadani Baitha , Harmita Harmita , Harahap Yahdiana , Hutabalian Hanna
Published: May 2019

Objective: The objective of this study was to obtain a simple and selective analysis method for determination of hydroquinone, tretinoin and betamethasone in whitening creams using reversed phase high-performance liquid chromatography (HPLC).

Methods: Reverse Phase HPLC was used for method development, validation studies, and sample analysis. The method was optimized by evaluating several parameters that affects extraction of the sample, composition and types of mobile phase and also flow rate. Chromatographic separation was optimized on a C18 column [Sunfire, 250 x 4.6 mm, 5µm] utilizing a mobile phase consisting acetonitrile, methanol (90:10 v/v) and slightly addition of glacial acetic acid to reach pH 5in the ratio of 30: 50:20 v/v at a flow rate of 0.8 ml/min with UV detection at 270 nm and 350 nm.

Results: The analytical methods fulfilled the validation requirements including accuracy, precision, linearity, selectivity, detection limits, and quantitation limits. The results showed the mean levels of hydroquinone, tretinoin and betamethasone in samples A and B were 1.78%; 0.07%; 0.12% and 2.00%; 0.07%; 0.13% respectively.

Conclusion: The method was successfully applied for the determination of cosmetic formulation containing hydroquinone, tretinoin and betamethasone simultaneously. There were seven samples analyzed and two samples were positive containing hydroquinone, tretinoin, and betamethasone.
Estudios de las condiciones óptimas para maximizar estabilidad física y oxidativa de un ingrediente vitamínico nanoencapsulado
Authors: Mujica Álvarez Javiera , Matiacevich Silvia , Bustos Rubén
Published: May 2019

El presente trabajo tuvo como objetivo evaluar el efecto de distintos materiales de pared, caseinato de sodio (CS) y un almidón modificado Capsul® (CAP), sobre la estabilidad física y oxidativa de nanoemulsiones con vitamina E para obtener un ingrediente vitamínico nanoencapsulado. Se estableció un diseño experimental Box-Behnken, en donde se analizaron tres factores: tipo de agente encapsulante (4% p/p CS/CAP/CAP+CS), concentración de surfactante Tween 80 (1-2% p/p) y tiempo de ultrasonido (1-3 min). Las variables de respuesta fueron el tamaño de nanocápsulas, índice de polidispersidad (PDI) y estabilidad oxidativa a 80,110 y 140 ºC, expresa como período de inducción (PI). A partir de las condiciones óptimas, se validó el modelo y se aumentó la concentración del agente encapsulante para mejorar la estabilidad física de las nanoemulsiones durante su almacenamiento (4 ºC-72 h). Estas nanoemulsiones fueron liofilizadas y se les evaluó el PI en comparación con la vitamina E libre y en nanoemulsión.

Se obtuvo un tamaño de partícula entre 20-100 nm con un PDI<0,5 en todas las condiciones experimentales, confirmándose la obtención de nanoemulsiones con una distribución de tamaño monomodal. Las condiciones óptimas fueron: caseinato de sodio como agente encapsulante, 1% p/p de Tween 80 y 3 min de ultrasonido. Sin embargo, la estabilidad física de esta nanoemulsión fue inferior a 2h. Por esto, se aumentó la concentración de caseinato de 4 a 8% p/p, lo que prolongó la estabilidad hasta 72 h a 4 ºC sin observar separación de fases. Para esta nanoemulsión, el tamaño de partícula fue 63 nm y el PI de 8,7, 4,4, 3 h para 80, 110, 140 ºC, respectivamente. El PI del polvo liofilizado fue 10,2, 4,4, 3 h, y para la vitamina E libre fue 3,6, 1,8, 1 h para 80, 110, 140 °C, respetivamente. El caseinato de sodio resultó ser mejor material de pared que el Capsul® ya que permitió mejorar la estabilidad oxidativa de las nanoemulsiones. El proceso de liofilización mejoró la estabilidad oxidativa de la vitamina en comparación con la nanoemulsión de vitamina E y la vitamina E libre.
Dermatofitos en roedores de Chile
Authors: Zaror Luis , Casas Sandra
Published: May 2019

En un estudio sobre la presencia de dennatofitos en ratas y ratones silvestres y de cautiverio, en Chile, sólo Trichophyton mentagropbytes fue aislado en el 2.5% de los animales. Se discute la importancia de estos roedores en lugares recreativos y en investigación biomédica
Myxomycetes ocorrentes nos brejos de Pernambuco (Brasil)
Authors: Lopes da Silva Maria Ivone , De Holanda Cavalcanti Laise
Published: May 2019

La presencia de 21 especies de Myxomycetes fue estudiada en 5 zonas "brejos" en el estado de Pemambuco, incluidos en los siguienles órdenes: Liceales, Trichiales, Physarales y Stemonitales. Los ''brejos'; preselltan un cOl/jullto de condicionesespeciales, altin,d (600-1056 m), alta pluviosidad, humedad (suelo-aire) y cobertura vegelal, condiciones que hacen del lugar Ul/ área higrófila dentro de regiolles semi-áreas.
Revisão de myxomycetes ocorrentes em cana.de.açúcar (saccharum spp.) Em Brasil
Authors: Dos Santos Eneida Jucene , De Holanda Cavalcanti Laise
Published: May 2019

Mediante la revisión de la literatura especializada se constató que la presencia de 33 especies de MYXOMYCETES en caña de azúcar (Saccharumspp.) en Brasil; las especies fueron encantadas en cañaveral y en bagazo de calia para fines industriales. Fuligo septica (Link) Wiggers, Craterium leucocephalum (Persoon) Ditmar y Lycogala epidendrum (L.) Fries son las especies más frecuentemente encontrados en este substrato.
The value-relevance of fundamental signals and the impact of financial regulations on security valuation and earnings management
Authors: Kwon Sung
Published: May 2019

This article investigates the value-relevance of earnings and financial analysts’ fundamental signals, as identified by prior research. We document four primary findings. First, consistent with the claims in the accounting literature, the value-relevance of ‘bottom line’ earnings has declined over time. Second, the combined value-relevance of earnings and financial analysts’ fundamental signals have also declined over time. Prior studies in this line of research have generated mixed evidence. In other words, some previous studies support an increase and some others find a decrease in the value-relevance of book values of net assets (common equity) over time. This study focuses on the financial analysts’ fundamental signals, not the book values of net assets, and the change in the degree of the value-relevance of those signals over time. Third, we find a negative correlation between firms’ excess returns and regulations, such as Sarbanes-Oxley (SOX) and Dodd-Frank, which are consistent with the claims of some prior studies that the implementation costs of the regulations may exceed their benefits for shareholders of the corporations affected by the regulations. Finally, we also report that the levels of opportunistic earnings management, reflected in some of those fundamental signals, have declined following these regulations.
Konwergencja typu sigma cen gruntów rolnych w państwach Unii Europejskiej
Authors: Twardowska Anna
Published: May 2019

W artykule poruszono problematykę zależności pomiędzy cenami ziemi rolniczej w państwach Unii Europejskiej. Celem artykułu jest próba uzyskania odpowiedzi na pytanie czy ma miejsce zmniejszanie się zróżnicowania poziomu cen gruntów rolnych w krajach Unii Europejskiej. Analizie poddano ceny gruntów rolnych w wybranych państwach UE w latach 2006 – 2016. Badaniu poddano występowanie konwergencji w trzech wymiarach: w całej Unii Europejskiej, pomiędzy państwami tzw. starej Unii oraz pomiędzy tzw. nowymi krajami UE. W wyniku przeprowadzonych analiz potwierdzono występowanie zjawiska sigma-konwergencji cen gruntów rolnych w całej UE. Stwierdzono również, że w tzw. nowych państwach UE oraz pomiędzy państwami należącymi do tzw. starych państw UE nie zachodzi zjawisko sigma-konwergencji cen gruntów rolnych.
Financial Sustainability and Value of Joint-Stock Companies from Food Industry in Central and Eastern Europe
Authors: Zabolotnyy Serhiy , Wasilewska Natalia , Wasilewski Mirosław
Published: May 2019

The research presents the analysis of relations between financial sustainability and value of joint-stock companies from food industry in Central and Eastern Europe. Increase of volume of assets, shareholders’ equity and revenues demonstrated an improvement of financial sustainability and resulted in growing valuations of companies in the study period. Sample business entities achieved relatively high liquidity and profitability that proved their financial sustainability in terms of risk and return. At the same time rising operating profit margins and liquidity ratios determined higher enterprise value of joint-stock companies. This emphasized a positive relation between enterprise value and financial sustainability. Joint-stock companies demonstrated a robust capital structure with a minor decrease of corporate debt in 2011-2015. However changes in sources of financing could provoke a trade-off between financial sustainability and enterprise value. According to a regression model factors positively influencing enterprise value included revenue, cash and cash equivalents, operating profit, current liabilities and shareholder’s equity. Stimulating revenue and increasing operating profit as well as maintaining higher cash balances improves financial sustainability while debt extension can significantly deteriorate continuity of business.
Wpływ zmian klimatu na efektywność wykorzystywania azotu oraz jego straty
Authors: Faber Antoni , Jarosz Zuzanna , Król Aleksandra
Published: May 2019

Celem badań było określenie przewidywanych plonów, efektywności wykorzystania N (NUE), wymywania N, emisji N2O i NH3 w zależności od zmian klimatu do 2050 r. Badania wykonano, z zastosowaniem modelu DNDC, dla okresów lat 1991-2010, 2011-2030 i 2031-2050 oraz 10 lokalizacji w Polsce. W symulacjach uwzględniono zmianowanie roślin: kukurydza na ziarno – jęczmień jary – rzepak ozimy – pszenica ozima, które uprawiano na glebach lekkich, średnich i ciężkich, przy nawożeniu wynoszącym odpowiednio: 140, 90, 160 i 120 kg N ha-1. Stwierdzono, że zmiany klimatu przyczynić się mogą do wzrostów plonów kukurydzy na ziarno (6-43%) i rzepaku ozimego (2-8%), spadków plonów pszenicy ozimej (od -18 do -5%) oraz nieistotnych zmian w plonach jęczmienia jarego. NUE wzrośnie w uprawie kukurydzy (2-17%), zmaleje w uprawach pszenicy ozimej (3-22%) i jęczmienia jarego (3-17%) oraz nie ulegnie zmianie w przypadku rzepaku ozimego. Zmiany NUE oraz straty N nie wpływały na konieczność zmniejszenia dawek azotu w przyszłej uprawie badanych roślin.
Price Behaviour and Market Integration: Preliminary Evidence
from the Ukrainian and European Union Rapeseed Markets
Authors: Hamulczuk Mariusz , Makarchuk Oksana , Sica Edgardo
Published: May 2019

This paper aims to provide preliminary evidence about the existence of horizontal integration between the rapeseed markets in Ukraine (UA) and the European Union (EU). To this end, both a trade analysis and a price analysis were carried out. In particular, the trade analysis was performed using yearly trade flows between the UA and EU, whereas price co-movement was assessed by means of linear vector error correction model (VECM) applied to weekly prices for rapeseed from 2008 to 2018. Our findings provide evidence of strong integration between the UA and EU markets in terms of the trade of rapeseeds, rape cake, and rape oil, as well as high horizontal rapeseed price transmission between the two economies.
Uwarunkowania zachowań konsumentów na rynku żywności ekologicznej
Authors: Kułyk Piotr , Dubicki Piotr
Published: May 2019

Poznanie zmieniających się potrzeb konsumentów jest ważnym elementem budowania przewagi konkurencyjnej przedsiębiorstwa. Celem artykułu jest przedstawienie zachowań konsumentów na lokalnym rynku produktów ekologicznych. W artykule przedstawiono zagadnienia związane z rynkiem żywności ekologicznej. Zdefiniowano i scharakteryzowano pojęcie produktu ekologicznego, omówiono kontrolę i certyfikację produkcji ekologicznej oraz czynniki wpływające na jakość żywności i popyt na produkty ekologiczne. Przeprowadzono badanie ankietowe na rynku lokalnym mające na celu scharakteryzowanie uwarunkowań zachowań konsumentów na rynku żywności ekologicznej. Na podstawie przeprowadzonych badań ankietowych i analizy danych statystycznych można zauważyć, że współczesny konsument jest świadomy tego co kupuje. Jakość i skład produktu to najważniejsze czynniki, które wpływają na podejmowane przez nich decyzję. Konsumenci coraz częściej rezygnują z konsumpcji żywności tradycyjnej na korzyść produktów ekologicznych.
3D/6D calibration and real-time focus shift compensation for automated 30 kW laser remote scanner
Authors: Cerwenka Georg , Wollnack Jörg , Krähling Thomas , Jayaprakash Rekha , Emmelmann Claus
Published: May 2019

Laser remote scanner (LRS) technology is one of the most promising topics in industrial manufacturing. To overcome current limitations for large-scale applications, an automated scanner system with 30 kW laser power has been developed. This system includes a stereo camera-based 3D vision for part detection as well as for task estimation. For this purpose, precise 3D/6D laser tool calibration has been conducted. To control the effect of focus shift due to high laser power level, additively manufactured lens holders and an easy to compute real-time focus shift compensation model have been investigated and are presented. Section II briefly introduces the 30 kW LRS concept, which includes demands and limitations. Furthermore, approaches for optical design and mechanical solutions, such as a gimbal-mounted mirror, are shown. The integration of the stereo camera system is considered. Section III describes laser tool calibration in 3D/6D, which is a prerequisite for absolute high-precision laser tool positioning of self-teaching automated LRS. A feasibility study has been performed. Laser beam induced thermal behaviors in the 30 kW LRS optics are discussed in Sec. IV, which causes refraction index and geometry changes that lead to focus shift. Additive manufactured internal cooled lens holder structure has been studied. A model for real-time compensation of focus shift has been investigated. It combines thermo-optic, stress-optic, and geometric effect with ABCD matrix analysis for optics. The topics are summarized, and an outlook is given on further applications for high-power LRS.
Do Cárcere ao Trabalho: A reinserção de ex-presidiárias no mercado de trabalho.
Authors: Lima dos Santos Rafaella
Published: May 2019

Nos últimos tempos observa-se um enorme aumento na população carcerária, os números encontrados são alarmantes, principalmente no que diz respeito às mulheres. O sistema prisional foi pensado por e para homens em uma época que privar uma pessoa da liberdade, era apenas punição. Hoje, a execução da pena não tem esse objetivo, mas criar condições para que o sujeito possa se reintegrar a sociedade. Portanto, conforme a Lei de Execução Penal é dever do Estado prevenir o crime e orientar o retorno à convivência em sociedade, sendo essa assistência estendida também ao egresso. Disposto isso, o trabalho é condição importante para que ele se integre e não haja reincidência criminal. Se para um homem já parece ser difícil o emprego, para a mulher egressa o processo é mais árduo, pois muitas vezes têm filhos e sofre um estigma muito maior para conseguir uma recolocação profissional.
Rousseau, Rio, and the Green Economy
Authors: Lopes Carlos
Published: May 2019

The Social Contract by Jean-Jacques Rousseau emerges as the most compelling and seminal piece of political theory. It explores legitimate political order in the context of classical republicanism. This paper delves into the following questions around Rousseau’s thesis: What would Rousseau make of the contemporary multilateralist surveillance regime, gridlocked in key areas that have direct links with human security? How would he square with a society that seems to be at odds with the nature– society equilibrium that he staunchly advocated for? Will Rousseau be able to lift today’s generation out of the collective myopia that focuses on individualism as the gateway to a prosperous future?
Ortaokul Öğrencilerinde Yalnızlığın Yordayıcısı Olarak Olumlu-Olumsuz Mükemmelliyetçilik
Authors: KARABABA Ali
Published: May 2019

Bu araştırmanın amacı ortaokul öğrencilerinde yalnızlık ile olumlu-olumsuz mükemmelliyetçilik arasındaki ilişkinin incelenmesidir. Araştırmadaki veri seti 2016-2017 eğitim-öğretim yılında, araştırmaya gönüllü olarak katılmayı kabul eden toplam 358 (169 kız-189 erkek) ortaokul öğrencisinden elde edilmiştir. Bu araştırma ilişkisel tarama modeli çerçevesinde gerçekleştirilmiştir. Araştırmada veri toplama araçları olarak “Olumlu ve Olumsuz Mükemmelliyetçilik Ölçeği” ve “UCLA Yalnızlık Ölçeği” kullanılmıştır. Analizler SPSS 16.0 paket programı yardımıyla test edilmiştir. Araştırma bulgularına göre yalnızlık olumlu mükemmelliyetçilik ile negatif; olumsuz mükemmelliyetçilik ile ise pozitif yönde anlamlı ilişki göstermektedir. Ayrıca, araştırma bulguları ortaokul öğrencilerinde olumlu mükemmelliyetçiliğin yalnızlığın negatif yönde; olumsuz mükemmelliyetçiliğin ise pozitif yönde anlamlı bir yordayıcısı olduğunu göstermiştir.
Riesgos no tan explícitos y peligros no tan solapados
Authors: Guemureman Silvia , Bianchi Eugenia
Published: May 2019

El artículo reflexiona sobre el riesgo y la peligrosidad como matrices de inteligibilidad para analizar los discursos que tematizan a jóvenes y adolescentes en relación a la responsabilidad penal. Se analizan ocho proyectos de ley con estado parlamentario durante el periodo legislativo 2018. Se postula como hipótesis que los discursos expresados en estos proyectos no constituyen bloques de sentido unitarios ni exclusivamente antagónicos, sino que exhiben una hibridación de sentidos, nociones y valoraciones. La frecuente exacerbación de la sensibilidad punitiva disparada por algún episodio delictivo en el cual participa un adolescente confiere al debate diferentes matices que expresan tensiones alrededor de tópicos diversos; entre ellos legalidad, punibilidad, potestad punitiva del estado, justicia, garantías, derechos y seguridad. En los textos legislativos coexisten concepciones sobre los sujetos destinatarios de la norma, en este caso, los adolescentes y jóvenes que infligen o presuntamente infligen la ley y alrededor de estos sujetos proliferan discursos que los ubican en fronteras móviles y difusas entre “riesgos”, “peligros” y “vulnerabilidades”. El objetivo del artículo es analizar los discursos legislativos en tanto conjugan diversas nociones de riesgo y peligrosidad articulados con otros conceptos provenientes de la arqueología foucaulteana, que remiten a estudios sobre gubernamentalidad y a la necesidad de gobierno y gestión de poblaciones.Las conclusiones muestran que las nociones de riesgo, peligrosidad y vulnerabilidad atraviesan los discursos trascendiendo las dicotomías sencillas, tales como tutelarismo-derechos; garantismo-punitivismo; progresividad-regresividad, justicia actuarial-justicia restaurativa. En tal sentido, el artículo busca ofrecer claves analíticas que aumenten la comprensión de esta problemática en Argentina.
Update on pathogenesis, diagnosis, and treatment of atopic dermatitis in dogs
Authors: Nuttall Timothy J. , Marsella Rosanna , Rosenbaum Michele R. , Gonzales Andrea J. , Fadok Valerie A.
Published: May 2019

Improved understanding of the pathogenesis of atopic dermatitis in dogs has led to more effective treatment plans, including skin barrier repair and new targeted treatments for management of allergy-associated itch and inflammation. The intent of this review article is to provide an update on the etiologic rationale behind current recommendations that emphasize a multimodal approach for the management of atopic dermatitis in dogs. Increasing knowledge of this complex disease process will help direct future treatment options.
Bilateral pararhinotomy with middle meatal antrostomy of the maxillary sinus in a rabbit (Oryctolagus cuniculus) with chronic rhinitis
Authors: Summa Noémie M. , Sanchez-Migallon Guzman David , Keller Krista A. , Woods Sarah Jones , Hawkins Michelle G. , Hunt Geraldine B.
Published: May 2019

CASE DESCRIPTION

A 4-year-old spayed female mixed-breed rabbit was evaluated because of a 3-year history of sneezing and nasal discharge that were refractory to medical management.

CLINICAL FINDINGS

Signs of chronic left-sided rhinitis and sinusitis were observed on physical examination and confirmed by CT evaluation. Lysis of the rostral aspect of the left maxillary bone and destruction of nasal turbinates were evident on CT images.

TREATMENT AND OUTCOME

Pararhinotomy of the left maxillary sinus through the facies cribrosa was performed. Purulent material was removed from the maxillary sinus recesses, a middle meatal antrostomy was completed to allow permanent drainage into the left middle nasal meatus, and the tissues were closed routinely. Microbial culture of a sample from the maxillary sinus recesses revealed Bordetella bronchiseptica, undetermined fastidious nonenteric bacteria, and Streptococcus viridans. Medical management was continued, and nasal discharge resolved but sneezing persisted. Increased sneezing and bilateral nasal discharge developed 1.5 years later; CT examination revealed right-sided rhinitis, and culture of a nasal swab sample revealed Bordetella spp, Staphylococcus spp, and Micrococcus spp. Right-sided pararhinotomy and middle meatal antrostomy were performed, and medical management continued. A subsequent recurrence was managed without additional surgery; 4 years after the initial surgery, the rabbit was still receiving medical treatment, with mild intermittent nasal discharge and sneezing reported.

CLINICAL RELEVANCE

This report describes a surgical approach for treatment of chronic rhinitis in companion rabbits with maxillary sinus involvement that included creation of a permanent drainage pathway from the maxillary sinus to the middle nasal meatus.
Leasing Puzzle in Polish Small Firms Listed on the Alternative Market
Authors: Jaszczuk Joanna , Białek-Jaworska Anna , Opolski Krzysztof , Sylwestrzak Marek , Trzpioła Katarzyna
Published: May 2019

In this article, we study the substitution between leasing and bank loans in financing the investment of small companies. The analysis is based on financial information about Polish companies listed on NewConnect, which used financial leasing in the period of 2012–2016. We argue that leasing and bank loans are the substitute in financing the investment of small companies. We estimate the probability of financial leasing and its size using the tobit and logit models. We find that financial leasing and bank loan, for Polish small companies, are complementarity. Our empirical results indicate that financial leasing and bank loans are complementary sources of financing investment in fixed assets. Also the higher the usage of financial leasing, the higher the likelihood that the enterprise is indebted because of long-term bank loan – complementarity.
EFEK ANTIBAKTERI EKSTRAK DAUN MIMBA (Azadirachta indica) TERHADAP PERTUMBUHAN Enterococcus faecalis SECARA IN-VITRO
Authors: Soraya Cut , - Sunnati , Wulandari Fenny
Published: May 2019

Perawatan saluran akar adalah perawatan yang dilakukan untuk mempertahankan gigi agar dapatberfungsi di lengkung gigi selama mungkin. Penyebab dominan dari kegagalan perawatan endodontikadalah adanya bakteri di dalam saluran akar. Bakteri yang paling sering ditemukan pada isolasi darigigi yang mengalami kegagalan perawatan saluran akar adalah Enterococcus faecalis (E.faecalis).Salah satu jenis tanaman herbal yang memiliki sifat antibakteri yang tinggi adalah tanaman mimba(A.indica). Tujuan penelitian ini untuk menganalisis efek antibakteri ekstrak daun mimba (A.indica)terhadap pertumbuhan E. faecalis. Penelitian ini merupakan penelitian eksperimental laboratorisdengan desain penelitian true experimental posttest only control group. Penelitian dilalukan denganmenguji ekstrak daun mimba (A.indica) pada konsentrasi 10%, 20%, 40%, 60%, 80% dan 100%terhadap pertumbuhan E. faecalis yang dilakukan di Laboratorium Mikrobiologi Fakultas KedokteranHewan (FKH) Universitas Syiah Kuala Banda Aceh. Hasil uji fitokimia yang dilakukan menunjukkanbahwa ekstrak daun mimba (A. indica) positif mengandung triterpenoid, phenolic compound, tanin,steroid dan saponin yang berperan sebagai antibakteri. Hasil uji efek antibakteri ekstrak daun mimba(A. indica) menunjukkan adanya pembentukan zona hambat di sekitar kertas cakram pada setiapkonsentrasi. Hal ini membuktikan bahwa ekstrak daun mimba memiliki efek antibakteri yangmemiliki kemampuan dalam menghambat pertumbuhan E. faecalis. Uji statistik digunakanmenggunakan one way ANOVA. Kemudian dilakukan uji lanjut (Post hoc test) menggunakan LeastSignificant Difference untuk menganalisis perbedaan efek antibakteri ekstrak daun mimba (A. indica)dalam konsentrasi 10%, 20%, 40%, 60%, 80% dan 100% terhadap pertumbuhan E.faecalis.Kesimpulan penelitian ini ekstrak daun mimba (A. indica) berpotensi menghambatpertumbuhan E. faecalis.Kata Kunci: Azadirachta indica, Enterococcus faecalis, perawatan saluran akar.
STUDI KASUS: “FRENEKTOMI SEBAGAI TERAPI PENDAHULUAN SEBELUM PERAWATAN ORTODONTIK” Laporan Kasus
Authors: - Sulistiawati , Hendiani Ina
Published: May 2019

Frenektomi frenulum labialis superior sering kali dilakukan untuk mengatasi masalah diastemasentral. Bedah frenektomi ini diharapkan akan memperbaiki estetik pasien dan biasanya diikutidengan perawatan ortodontik. Pasien wanita berusia 19 tahun datang ke Klinik Residen PeriodonsiaFakultas Kedokteran Gigi Universitas Padjadjaran dirujuk dari Klinik Ortodonsia untuk dilakukanfrenektomi, setelah dilakukan pemeriksaan diketahui terdapat aberansia frenulum labialis superioryang menjadi penyebab diastema sentral. Pada kasus ini dilakukan bedah frenektomi dengan teknikklasik menggunakan hemostat dan skalpel dengan tujuan memperbaiki perlekatan frenulum labialissuperior yang menyebabkan diastema sentral. Perdarahan yang terjadi saat bedah dapat dikontroldengan baik. Hasil perawatan menunjukkan perlekatan frenektomi diperbaiki dan diikuti denganperawatan ortodontik untuk menutup diastema sentral.Kata kunci: Aberansia frenulum labialis superior, diastema sentral, frenektomi, teknik klasik
STUDI KEKASARAN PERMUKAAN ANTARA RESIN AKRILIK HEAT CURED DAN TERMOPLASTIK NILON YANG DIRENDAM DALAM KOPI ULEE KARENG (Coffea robusta)
Authors: Sundari Iin , Rahmayani Liana , Serpita Deliga
Published: May 2019

Resin akrilik heat cured merupakan material yang paling sering digunakan dalam pembuatan basisgigi tiruan. Seiring perkembangan ilmu pengetahuan dan teknologi, termoplastik nilon juga menjadipilihan bagi material basis gigi tiruan. Material basis gigi tiruan mempunyai kekurangan pada sifatfisiknya, diantaranya adalah kekasaran permukaan. Kekasaran permukaan dapat terjadi pada resinakrilik heat cured dan termoplastik nilon diantaranya disebabkan karena terpaparnya material denganlarutan yang mengandung asam, salah satunya adalah kopi. Penelitian ini dilakukan untuk mengetahuiperbedaan kekasaran permukaan antara resin akrilik heat cured dan termoplastik nilon sebelum dansetelah direndam dalam larutan kopi Ulee Kareng (Coffea robusta). Jumlah spesimen pada penelitianini ada 8 spesimen, 4 resin akrilik heat cured Meliodent dan 4 termoplastik nilon BIO TONE denganukuran 20x20x2 mm. Spesimen direndam dalam larutan kopi selama 4 hari (mensimulasikanmengkonsumsi larutan kopi selama 1 tahun) dengan larutan kopi diganti setiap hari. Kekasaranpermukaan sebelum dan setelah perendaman diukur menggunakan alat surface roughness tester. Hasiluji t berpasangan pada kedua kelompok menunjukkan perbedaan bermakna kekasaran permukaansebelum dan setelah perendaman (p0.05), hasil uji t tidak berpasangan antara resin akrilik heat cureddan termoplastik nilon sebelum perendaman menunjukkan terdapat perbedaan bermakna (p0.05) dansetelah perendaman juga menunjukkan perbedaan bermakna (p0.05). Nilai kekasaran permukaanresin akrilik heat cured lebih tinggi dibandingkan termoplastik nilon setelah direndam dalam kopiUlee Kareng (Coffea robusta).Kata Kunci: Resin akrilik, termoplastik nilon, kopi
Keragaman Morfologi dan Kandungan Tanin pada Tanaman Leunca [Solanum nigrum (L.)]
Authors: Nadila Dea , , Sobir , Syukur Dan Muhamad
Published: May 2019

Black nightshades [Solanum nigrum (L.)] is an indigenous vegetable originatied from tropical and subtropical regions. In Indonesia, black naightshades widely spread in Java, especially West Java. Black nightshades has a bitter taste caused by the content of tannins. The objective of this study was to identify and analyze the morphological and tannin content of 20 black nightshades accessions. The research was started with germplasm exploration in November 2015-February 2016, followed by planting and analysis until September 2016 at a laboratory of the Center for Tropical Horticultural Studies (PKHT) IPB. The experiment was arranged in a single-factor randomized complete block design with three replications. The results from cluster analysis based on morphological variability showed that the accessions of black nightshades can be grouped into two groups. The accessions had different fruit tannin contents, and some accessions can be selected for breeding material.Keywords: group analysis, indigenous vegetable, qualitative character, quantitative character
Potensi Hasil dan Toleransi Galur-galur Inbrida Sorgum pada Tanah dengan Hara Fosfor Rendah
Authors: Momongan Jorex Daniel , Trikoesoemaningtyas Trikoesoemaningtyas , Wirnas Desta , Sopandie Dan Didy
Published: May 2019

Sorghum development in Indonesia is directed towards cultivation in dryland and acid soil with low P availability. This research was aimed to obtain information on the performance of sorghum traits for selection in P deficient environment at early vegetative phase (3 weeks after planting), agronomic and yield potential traits in both P sufficient and P deficient environments, also to select high productivity sorghum genotypes which could tolerate P deficiency. The genetic materials used were 19 F7 recombinant inbred lines from a cross of B69 x Numbu developed under optimum condition (indirect breeding) by single seed decent. Variety Numbu and B69 used as checks. This research was conducted at The Indonesian Center for Biotechnology and Agriculture Plant Genetic Resources experimental field, Bogor, from May to September 2017. The experiment used a randomized complete block design with 3 replicates. The results showed that agronomic and yield traits varied among inbred lines under low P condition and optimum P condition. Adaptive lines showed better growth and yield compared to sensitive ones under low P condition. Plant height, panicle weight, and grain weight per panicle had high estimates of broad sense heritability. Selection based on stress tolerance index was able to identify inbred lines 286-6, 115-9, 114-7, 331-8, 170-9, 151-8, 104-7, 413-7, 68-5, 315-6, and 341-7 as tolerant to low P condition.Keywords: heritability, indirect breeding, optimum P condition, stress tolerance index
“Extra-full” multipurpose dry-cargo vessel of RSD59 project for all types of dry cargoes
Authors: Egorov Gennadiy , Tonyuk Valeriy , Durnev Evgeniy
Published: May 2019

This paper justifies main parameters for a multi-purpose dry-cargo vessel and describes its concept design developed as per MEB procedures.
Sistem Peringatan Dini Bencana Longsor Menggunakan Sensor Accelerometer dan Sensor Kelembabapan Tanah Berbasis Android
Authors: Artha Onny Octaviani , Rahmadya Budi , Putri Rahmi Eka
Published: May 2019

Landslide is one of the most frequent disasters in Indonesia, especially in hilly areas, valleys, and volcanoes. Geographical conditions that are generally mountainous areas and have slopes make the soil unstable. As a result, when the movement of the land becomes easy to slide. Ground shifts and excessive water content are the main causes of landslides. The landslide disaster can cause many losses, such as to cause loss of life, can disrupt transportation facilities, damage agricultural land, and various other consequences. In this study used sensor MPU6050 and Soil Moisture and NodeMcu sensors to provide early warning of landslides. Linear acceleration is detected by using MPU6050 sensor and will define the ground movement based on the scenarios developed in this study. Soil moisture sensor detects soil moisture. The result of soil movement detection and soil moisture is stored in file storage. When ground detection and soil moisture is greater than 51%, the alarm alert is sent to the user's smartphone with a 100% success percentage.
Identifikasi Penyakit Diabetes Mellitus Melalui Nafas Berbasis Sensor Gas Dengan Metode Fast Fourier Transform dan Backpropagation
Authors: Hersyah Mohammad Hafiz , Andrizal Andrizal , Revinessia Revinessia
Published: May 2019

The purpose of this research is to detect whether a person has diabetes mellitus or not. In people with diabetes mellitus uncontrolled will result in a decline in the rate of saliva that results in bad breath. The system uses the sensor TGS 2602 and MQ 4. It's function is to detect the levels of Hydrogen Sulfide and Methan in a person’s breath. The decision is made by using the neural network with a backpropagation method. The result for 5 (five) tests of diabetes mellitus samples can be detected with a success rate of 80%, whereas using random samples, the test detected with detected with a success rate of 80% samples that didn’t contain diabetes mellitus. This system could provide a solution for testing if a person is suffering from diabetes mellitus
The Use of Naive Bayes for Broiler Digestive Tract Disease Detection
Authors: Cahyaningtyas Christyan , Purnomo Hindriyanto Dwi , Kristianto Budi
Published: May 2019

Broiler chicken is a species of chicken that have high productivity. In order to get a good quality of chicken, good treatments of the breeding factors is needed, so the chicken will not easily infected by diseases. Gastrointestinal diseases are common disease that infects chickens. The mortality level caused by gastrointestinal diseases is considered high. This study is designed to address the problem by developing a system using the Naive Bayes algorithm. 60 chicken data samples were used, and the result shows that Naive Bayes might be used to detect gastrointestinal diseases among chickens with accuracy level of 93.3%. The number was confirmed by using confusion matrix evaluation method, and gave same level of accuracy compared to the expert judgments.
The role of knowledge management for education in Nigeria
Authors: J. IKENWE, Ogagaoghene U. IDHALAMA Christopher A. OMIGIE, Iguehi
Published: May 2019

The study investigates the pivotal role of knowledge management within the academic parlance which has a positive spiral and multiplier effects in a given economy by way of taking our dear country from the shackles of hunger, poverty, insecurity etc. It is clear that the effectiveness and efficiency of any organization/economy rest squarely on its level of knowledge: tacit and explicit. However, this knowledge must be critically studied, tapped, stored and disseminated. This study therefore looked at the concept of knowledge, management, its relevance and role in effective academic system and how knowledge management could contribute in taking a country like Nigeria out of the woods.
PERILAKU MAKAN DAN KESEJAHTERAAN SUBJEKTIF MAHASISWA
Authors: Fitriana Nina
Published: May 2019

Mahasiswa memiliki beragam tanggung jawab baik secara akademis maupun non akademis yang harus dijalani. Kesuksesan menjalankan berbagai peran tersebut sangat dipengaruhi oleh bagaimana ia dapat menikmati dan merasa bahagia dengan proses yang dijalani. Kebahagiaan atau sering diistilahkan dengan subjective well being menjadi salah satu hal yang sangat mempengaruhi kesuksesan mahasiswa dalam menjalani kehidupannya. Terdapat beberapa faktor yang dapat mempengaruhi subjective well being, diantaranya adalah perilaku makan. Dengan demikian, penelitian ini bertujuan untuk melihat apakah terdapat hubungan perilaku makan dengan subjective well being. Sehingga hipotesis penelitian ini adalah terdapat hubungan positif antara perilaku makan dan subjective well being. Jumlah subjek dalam penelitian ini adalah 65 mahasiswa. Metode pengumpulan data menggunakan skala Subjective Well Being dan Eating Habit Questionnaire. Skala Subjective Well Being terdiri dari 3 sub skala, yaitu Satisfaction With Life Scale dengan 5 aitem, Positive Affect dengan 9 aitem, dan Negative Affect dengan 9 aitem. Sedangkan skala Eating Habit Questionnaire terdiri dari 21 aitem. Teknik analisis korelasi product moment digunakan untuk mengetahui hubungan tersebut . Hasil penelitian dinyatakan bahwa tidak ada hubungan antara perilaku makan dengan subjective well being.
Os efeitos das emoções no ensino-aprendizagem de inglês e na formação do futuro professor: uma análise com base no feedback corretivo oral
Authors: Battistella Tarsila Rubin
Published: May 2019

Resumo

Este trabalho apresenta uma análise das emoções em um ambiente presencial de ensino, bem como a relação que pode ser estabelecida entre o feedback corretivo oral e as emoções, por meio da triangulação de dados, e que podem influenciar na formação do futuro professor e no ensino-aprendizagem de línguas. Procuramos ainda identificar as reações dos aprendizes ao feedback corretivo oral recebido pela professora e/ou pelo colega no contexto formal de ensino-aprendizagem de inglês. Os resultados demonstram que os aprendizes apresentam sentimentos distintos quanto à correção, estando relacionados diretamente às crenças destes e que isso pode influenciar diretamente no sucesso ou no fracasso em sua caminhada para a aprendizagem e para sua atuação profissional.  

Palavras-chave: Emoções. Língua estrangeira. Língua inglesa. Feedback corretivo oral. Teoria sociocultural.

 

Abstract

In this article we present an analysis of emotions in a classroom teaching setting as well the relation that can be established between the oral corrective feedback and emotions, by data triangulation and how it can enhance the future teacher formation and the language teaching and learning. The article also tries to identify learners` reaction to the oral corrective feedback given by the teacher or by their peer in the english classroom setting. The results show that learners present different feelings regarding the corrective feedback and this can be directly related to their beliefs. These results can also have an effect on the success or failure of learners` learning and professional development.

Keywords: Emotions. Foreign language. English language. Oral corrective feedback. Sociocultural theory.
Análise de textos multimodais em capas de materiais didáticos de Português LE/L2
Authors: Castro Giuliano Pereira de Oliveira
Published: May 2019

Resumo

O ensino de línguas é norteado pela concepção acerca da natureza da linguagem, seu funcionamento e função nas práticas sociais, bem como das concepções e dos postulados sobre como se deve ensinar e aprender línguas. O escopo da pesquisa em Linguística Aplicada é bastante amplo no que tange à natureza dessa concepção, denominada abordagem, presente em todas as esferas do complexo processo de ensino e aprendizagem de línguas, e uma dessas esferas é o material didático. Grandes mudanças nos paradigmas de ensino de línguas bem como o advento de novas tecnologias têm transformado o material didático, conferindo-lhe cada vez mais uma natureza multimodal (vários modos semióticos para produção de significado). Nosso enfoque neste trabalho é a investigação acerca da relação existente entre a multimodalidade textual presente nas capas de três materiais didáticos para ensino de Português para estrangeiros publicados no Brasil e a abordagem que subjaz a esses materiais, tendo em vista os textos multimodais como enfoque e ponto de partida. O estudo evidencia a natureza multimodal da linguagem e conclui que um foco mais intenso na abordagem comunicativa, com ênfase nos processos de interação, requer que texto (linguagem verbal) e imagem (não verbal) sejam combinados de forma que promovam um contexto comunicativo profícuo.

Palavras-chave: Material didático. Multimodalidade. Abordagem.

 

Abstract

Language instruction is guided by the conception of the nature of language, its function and role in social practices, as well as conceptions and postulations about how one should teach and learn languages. The scope of research in Applied Linguistics is quite broad concerning the conception of that nature, known as approach, present in all spheres of the complex process of teaching and learning languages. One of those spheres is instructional materials. Major changes in the paradigms of language teaching as well as the advent of new technologies have transformed teaching materials, attributing them an increasingly multimodal nature (several semiotic modes for the production of meaning). Our focus on this paper is to research the relationship between the textual multimodality present in three coursebook covers for teaching Portuguese to foreigners published in Brazil, and the approach that underlies these materials, having the texts as our multimodal focus and starting point. The study highlights the multimodal nature of language and concludes that a more intense focus on the communicative approach, with emphasis on interaction processes, requires that text (verbal language) and image (non verbal) are combined to promote a meaningful communicative context.

Keywords: Language teaching materials. Multimodality and foreign language teaching. Approaches.