bluuebunny/crossref_metadata_2025 huggingface dataset:
The Infrared Physics of Bad Theories
Authors: Assel Benjamin , Cremonesi Stefano
Published: September 2017

We study the complete moduli space of vacua of 3d
\mathcal{N}=4𝒩=4U(N)U(N)
SQCD theories with N_fNf
fundamentals, building on the algebraic description of the Coulomb
branch, and deduce the low energy physics in any vacuum from the local
geometry of the moduli space. We confirm previous claims for good and
ugly SQCD theories, and show that bad theories flow to the same
interacting fixed points as good theories with additional free twisted
hypermultiplets. A Seiberg-like duality proposed for bad theories with
N \le N_f \le 2N-2N≤Nf≤2N−2
is ruled out: the spaces of vacua of the putative dual theories are
different. However such bad theories have a distinguished vacuum, which
preserves all the global symmetries, whose infrared physics is that of
the proposed dual. We finally explain previous results on sphere
partition functions and elucidate the relation between the UV and IR
RR-symmetry
in this symmetric vacuum.
Implementacja XIII Dyrektywy do polskiego porządku prawnego – zagadnienia wybrane
Authors: Rutkowska Ewelina
Published: September 2017

Tematem artykułu jest implementacja wybranych postanowień XIII Dyrektywy do polskiego porządku prawnego. Szczegółowo opisano obowiązek wystosowania wezwania do zapisywania się na sprzedaż lub zamianę akcji publicznej spółki akcyjnej w przypadku jej wrogiego przejęcia. Scharakteryzowano zasady neutralności i przełamania recypowane do ustawy o ofercie publicznej. Poddano ocenie prawidłowość implementacji XIII Dyrektywy do polskiego porządku prawnego oraz dopuszczalność stosowania środków obrony przed wrogim przejęciem.
Usługi płatnicze realizowane urządzeniami mobilnymi – prawne aspekty funkcjonowania na rynku polskim (ze szczególnym uwzględnieniem procesu autoryzacji transakcji)
Authors: Oppeln – Bronikowski Jerzy
Published: September 2017

Artykuł dotyczy płatności mobilnych (płatności dokonywanych za pomocą urządzeń mobilnych), opartych o usługi takie jak Android Pay, Samsung Pay czy Apple Pay. Celem artykułu jest przedstawienie podstawowych zagadnień, jakie pojawiają się na tle tego typu usług w odniesieniu do mających zastosowanie do przedmiotowego zagadnienia regulacji prawa polskiego (Prawa bankowego, ustawy o usługach płatniczych). Autor dokonuje analizy procesu dokonywania płatności uwzględniającego wykorzystanie jedynie karty płatniczej i porównania tej usługi do tej opartej na wykorzystaniu urządzeń mobilnych. Artykuł obejmuje wybrane problemy natury prawnej wynikające z różnic pomiędzy obiema procedurami m.in. odpowiedzialność wydawcy karty płatniczej za nieautoryzowane płatności oraz związane z nimi obowiązki użytkownika karty płatniczej.
The PI3K Pathway at the Crossroads of Cancer and the Immune System: Strategies for Next Generation Immunotherapy Combinations
Authors: Collins Dearbhaile C. , Chenard-Poirier Maxime , Lopez Juanita S.
Published: September 2017

Immunotherapy has led to a paradigm shift in the treatment of some malignancies, providing
long-term, durable responses for a subset of patients with advanced cancers. Increasingly, research
has identified links between the immune system and critical oncogenic growth factor pathways.
The phosphoinositide 3-kinase (PI3K)-AKT-mTOR cascade is frequently hyperactivated in
cancer, and plays an integral role in many cellular processes including tumour growth and survival
and can underlie resistance to therapies.

In this review, we first summarize two key learnings from the initial studies of inhibitors of this
pathway, including the profile of immune-related adverse events such as colitis, transaminitis and
pneumonitis and the increased incidence of infections with the majority of agents that target the
PI3K-AKT-mTOR pathway. We then discuss recent advances in our understanding of the role of
this pathway in the tumour micro-environment, and in the regulation of innate and adaptive immune
responses, and propose synergistic combination strategies with PI3K-network inhibitors and cancer
immunotherapy.
Molecular Biological Methods in Environmental Engineering
Authors: Li Chunying , Xia Fujun , Zhang Yuhua , Chang Chein‐Chi , Wei Dong , Wei Li
Published: September 2017

Microorganisms can respond fast to the environmental changes, and well suited for environmental assessment. DNA and RNA are generally extracted by extraction kits. After extraction, molecular biological methods including genomics, transcriptomics, proteomics and metabolomics are applied to characterize the genetic and functional diversity of microorganisms. Quantitative PCR, FISH and mass sequence of amplicons are also described. This review provides environmental engineers and microbiologists an overview of important advancements in molecular techniques and highlights the application of these methods in diverse environments.
Physico‐Chemical Processes
Authors: Hua Bin , Xiong Huixin , Kadhom Mohammed , Wang Lei , Zhu Guocheng , Yang John , Cunningham Gary , Deng Baolin
Published: September 2017

This review is on the research literature published in 2016 related to the physico‐chemical processes for water and wastewater treatment. The review is divided into granular and membrane filtration, sedimentation, coagulation/flocculation, flotation, oxidation, and adsorption.
Modeling, Instrumentation, Automation, and Optimization of Water Resource Recovery Facilities
Authors: Sweeney Michael W. , Kabouris John C.
Published: September 2017

A review of the literature published in 2016 on topics relating to water resource recovery facilities (WRRF) in the areas of modeling, automation, measurement and sensors and optimization of wastewater treatment (or water resource reclamation) is presented.
Food‐Processing Wastes
Authors: Frenkel Val S. , Cummings Gregg A. , Maillacheruvu K.Y. , Tang Walter Z.
Published: September 2017

Literature published in 2016 and early 2017 related to food processing wastes treatment for industrial applications are reviewed. This review is a subsection of the Treatment Systems section of the annual Water Environment Federation literature review and covers the following food processing industries and applications: general, meat and poultry, fruits and vegetables, dairy and beverage, and miscellaneous treatment of food wastes.
Mine Drainage: Research and Development
Authors: Wei Xinchao , Zhang Shicheng , Han Yuexin , Wolfe F. Andrew
Published: September 2017

This review summarizes the recent research and development pertaining to the topic of mine drainage which were published in 2016 and early 2017. The review includes three main sections: Mine Drainage and its Environmental Impact, Prediction and Prevention, and Treatment Technologies. The first section covers the characterization of mine drainage and its related environmental impacts, including three subsections focused on physiochemical characterization, microbiological characterization, and environmental impacts. The second section of the review is divided into two subsections focused on either the prediction or prevention of acid mine drainage. The final section focuses on treatment technologies for mine drainage, including physiochemical treatment, biological treatment, passive treatment, and beneficial uses of mine drainage and treatment wastes
Pulp and Paper Mill Effluent Management
Authors: Buchanan Ian D.
Published: September 2017

This is a review of literature published in 2016 related to the prevention of water pollution by or recovery of beneficial materials from wastewater produced in the pulp and paper industry. This review includes the following sections: pulp and paper wastewater management, pollution avoidance, process modelling, physical and chemical treatment, biological treatment, phytoremediation and value added materials.
Textiles
Authors: Choudri B.S. , Charabi Yassine , Baawain Mahad , Ahmed Mushtaque
Published: September 2017

A review of the literature published in 2016 on topics relating to the treatment alternatives for wastewater from the textile industries is presented. This review is divided into the following sections: a brief introduction on the implementation of the Best Available Techniques into textile industry, a review of the more promising treatment technologies distinguished into physico‐chemical, biological and combined processes.
Groundwater Pollution and Vulnerability Assessment
Authors: Kurwadkar Sudarshan
Published: September 2017

Groundwater is a critical resource that serve as a source of drinking water to large human population and, provide long‐term water for irrigation purposes. In recent years; however, this precious resource being increasingly threatened, due to natural and anthropogenic activities. A variety of contaminants of emerging concern such as pharmaceuticals and personal care products, perfluorinated compounds, endocrine disruptors, and biological agents detected in the groundwater sources of both developing and developed nations. In this review paper, various studies have been included that documented instances of groundwater pollution and vulnerability to emerging contaminants of concern, pesticides, heavy metals, and leaching potential of various organic and inorganic contaminants from poorly managed residual waste products (biosolids, landfills, latrines, and septic tanks etc.). Understanding vulnerability of groundwater to pollution is critical to maintain the integrity of groundwater. A section on managed artificial recharge studies is included to highlight the sustainable approaches to groundwater conservation, replenishment and sustainability. This review paper is the synthesis of studies published in last one year that either documented the pollution problems or evaluated the vulnerability of groundwater pollution.
Thermal Effects
Authors: Xu Dong , Zhang Panyue , Ye Jie , Zhang Haibo , Liu Jianbo , Yan Li , Wang Bei , Huang Xiaoding , Zeng Guangming
Published: September 2017

This review focuses on the research literatures published in 2016 relating to thermal effects in water pollution control. This review is divided into five sections: biological nitrogen removal, organic pollutant degradation, resource recovery, pretreatment and anaerobic digestion, microbial community.
Emerging Pollutants – Part I: Occurrence, Fate and Transport
Authors: Tang Yankui , Peng Xiaoyu , Yang Weiwei , Zhang Yue , Yin Maozhong , Liang Yan , Dong Zhanfeng
Published: September 2017

Emerging Pollutants‐Part I: Occurrence, Fate, and Transport is a sequel of Emerging Pollutants (EPs). The aims of this paper is to collect the relevant literature published in 2016 worldwide and analyze the knowledge and technologies developed in the aspects of screening, monitoring, occurrence, transport, fate, environmental toxicity and management of EPs that are relevant to water and wastewater.
Land use and land cover dynamics in the dehesa of Sierra Morena Biosphere Reserve (Sierra Norte de Sevilla Natural Park, Spain), 1956-2007
Authors: Mancilla Leytón Juan Manuel , Puerto Marchena Antonio , Martín Vicente Ángel
Published: September 2017

The dehesa, a representative savanna-like ecosystem type, has played and plays an important economic, ecological and social role, in addition to the valuable environmental services that it provides. The present study is focused on the analysis of the changes in the land use /cover of the dehesa in the Sierra Norte de Sevilla Natural Park (Sierra Morena Biosphere Reserve) during the last 50 years. In order to estimate the consequences that the change of land uses and, the activities that are carried out on it have on the dynamics of the dehesa, a diachronic analysis was performed for the period 1956-2007 using the digital geographic information available. The most important changes observed were related to: i) the increase of urban areas, water surface area, reforestation areas, eroded areas, mining areas and dumping sites; and ii) the decrease of cultivation areas, dehesa, scrubland and pastureland. The changing dynamics did not strictly respond only to phytosociological aspects, but it is necessary to explain the evolution of the landscape from the complex balance between biophysical and socioeconomic dynamics, where the current environmental changes also make it very difficult to ensure the persistence of this ecosystem. The present legislation promotes the development of a clear and up-to-date diagnosis of the problems that this ecosystem is facing. In this sense, the geographic information systems may be very useful at establishing the guidelines for the conservation and regeneration of the dehesas, and at spreading their environmental values.
Instructional Video and Medical Student Surgical Knot-Tying Proficiency: Randomized Controlled Trial (Preprint)
Authors: Bochenska Katarzyna , Milad Magdy P , DeLancey John OL , Lewicky-Gaupp Christina
Published: September 2017

BACKGROUND

Many senior medical students lack simple surgical and procedural skills such as knot tying.

OBJECTIVE

The aim of this study was to determine whether viewing a Web-based expert knot-tying training video, in addition to the standard third-year medical student curriculum, will result in more proficient surgical knot tying.

METHODS

At the start of their obstetrics and gynecology clerkship, 45 students were videotaped tying surgical knots for 2 minutes using a board model. Two blinded female pelvic medicine and reconstructive surgery physicians evaluated proficiency with a standard checklist (score range 0-16) and anchored scoring scale (range 0-20); higher numbers represent better skill. Students were then randomized to either (1) expert video (n=26) or (2) nonvideo (n=24) groups. The video group was provided unlimited access to an expert knot-tying instructional video. At the completion of the clerkship, students were again videotaped and evaluated.

RESULTS

At initial evaluation, preclerkship cumulative scores (range 0-36) on the standard checklist and anchored scale were not significantly different between the nonvideo and video groups (mean 20.3, SD 7.1 vs mean 20.2, SD 9.2, P=.90, respectively). Postclerkship scores improved in both the nonvideo and video groups (mean 28.4, SD 5.4, P<.001 and mean 28.7, SD 6.5, P=.004, respectively). Increased knot board practice was significantly correlated with higher postclerkship scores on the knot-tying task, but only in the video group (r=.47, P<.05).

CONCLUSIONS

The addition of a Web-based expert instructional video to a standard curriculum, coupled with knot board practice, appears to have a positive impact on medical student knot-tying proficiency.
Developing of Total Suspended Sediment Model Using Landsat-8 Satellite Image and In-Situ Data at The Surabaya Coast, East Java, Indonesia
Authors: Hariyanto Teguh , Krisna Trismono C. , Khomsin Khomsin , Pribadi Cherie Bhekti , Anwar Nadjadji
Published: September 2017

The decrease of coastal-water quality in the Surabaya coastal region can be recognized from the conceentration of Total Suspended Sediment(TSS ) . As a result we need a system for monitoring sediment concentration in the coastal region of Surabaya which regularly measures TSS. The principle to model and monitor TSSconcentration using remote sensing methods is by the integration of Landsat-8OLI satellites image processing using some ofTSS-models then those are analyzed for looking its suitability with TSS value direcly measured in the field ( in-situ measurement). The TSS value modeled from all algorithms validated usingcorrelation analysis and linear regression . The result shows that TSS model with the highest correlation value is TSS algorithm by Budiman (2004)with r value 0.991. Hence this algorithm can be used to investigate TSS-distribution which represent the coastal water quality of Surabaya with TSS value between 75 mg/L to 125 mg/L.
Sandbar Formation in the Mesjid River Estuary, Rupat Strait, Riau Province, Indonesia
Authors: Rifardi Rifardi , Badrun Yeeri
Published: September 2017

At the aim to clarify the relationship between the sandbar  formation and lithogeneous sediment discharges, the sedimentological aspects of the Mesjid River Estuary are revealed by various analysis. The samples of bottom surface sediments and the suspended sediment were collected at 50 stations in the estuary using grab and van dorm samplers. Oceanographic observation were also carried out  at the stations. The Mesjid River Estuary receives lithogeneous sediments mainly from the Mesjid River’s drainage areas which play important role on the formation of sandbar which is shown by  a belt-like area (0.5-1.0 m depth) in the area off the river mouth. The sandbar might become a sandbank in 20 to 40 years later. High suspended sediment up to 354.61 mg/l indicates the river mouth receives lithogeneous sediments. Total of 926  ton/day of the sediments supplied by the river are deposited 0.024 m/year into the area.
Keragaman di Indonesia dan Politik Pengakuan (Suatu Tinjauan Kristis)
Authors: Rahayu Mustaghfiroh
Published: September 2017

Dalam bahasa Indonesia ada istilah khusus untuk merujuk pada keberagaman, yaitu kebhinnekaan, meski demikian, pengertian atas konsep mengenai pluralisme dan multikulturalisme tetap populer digunakan dalam wacana sehari-hari mengenai keragaman di Indonesia. Dalam konteks ini, literaturliteratur di Indonesia tidak membedakan secara subtansial antara keduanya. Tanpa mengindahkan beban teoretis dari dua istilah tersebut, konsep pluralisme dan multikulturalisme digunakan saling bergantian untuk merujuk apa yang disebut keragaman. Oleh karena itu, artikel ini mencoba untuk melihat ulang (meninjau) secara kritis definisi mengenai pluralisme dan multikulturalisme dalam kaitannya dengan studi keragaman di Indonesia. Secara khusus, artikel ini juga menilik sejarah kontekstual atas dua istilah tersebut dan implikasinya dalam kebijakan akomodasi keragaman termasuk politik pengakuan (recognition) di Indonesia.
Componentes estruturadores de uma ideia para o design de produto e serviços
Authors: Sete Câmara Jocely
Published: September 2017

Este artigo reproduz os dados resultantes de um levantamento, registro e exame das formulações conceituais do Design, do Marketing e da Sustentabilidade. Acredita-se que tanto o Design como o Marketing são campos de conhecimento parceiros, complementares e transversais, tendo portanto um natural potencial de sinergia para a construção de projetos consistentes e duráveis. O procedimento foi retirar das designações examinadas, o que se considerou conceito central, sintetizando-o por uma palavra. Assim foi feito para cada campo, e em seguida entre eles, observando-se suas tangências. Encontrou-se definições que se correspondem, que se sobrepõem e que se agregam. Também os respectivos fatores projetuais e condicionais foram reunidos pelas suas correspondências, sobreposições, e complementaridades, originando uma contribuição material na forma de uma ferramenta criativa, analítica e gerativa para o desenvolvimento de soluções mais sustentáveis. Esta é uma sugestão de ajuda para a interação e integração de saberes.
Validez diagnóstica de la endosonografía biliopancreática en el diagnóstico de colangitis aguda secundaria a obstrucción biliar
Authors: Ricardo Ramírez Andrés Mauricio , Arango Molano Lázaro Antonio
Published: September 2017

El diagnóstico de las colangiopatías obstructivas por endosonografía biliopancreática (EUS, por sus siglas en inglés), se ha estudiado en profundidad y existe un extenso reconocimiento de su papel para el diagnóstico de coledocolitiasis, tumores de la encrucijada biliopancreática y síndromes de compresión extrínseca de la vía biliar. La colangitis, complicación más frecuente de la obstrucción biliar y responsable de gran parte de su morbimortalidad, no se ha relacionado en forma suficiente con los hallazgos endosonográficos. Nuestro estudio buscó definir la validez diagnóstica de la endosonografía en los pacientes con colangitis aguda con el fin de limitar la morbimortalidad del retraso diagnóstico. Se realizó un estudio descriptivo, analizando las historias clínicas de pacientes sometidos a endosonografía biliopancreática, por ictericia obstructiva de cualquier etiología y quienes posteriormente fueron llevados a colangiopancreatografía retrógrada endoscópica (CPRE), para manejo de obstrucción biliar. Comparamos los hallazgos endosonográficos compatibles con colangitis aguda (engrosamiento de la vía biliar de 1,5 mm o >, presencia de halo pericolangítico de al menos 1,5 cm de longitud y presencia de contenido de ecogenicidad mixta en el interior de la vía biliar) con el drenaje purulento durante la CPRE.Se encontró una alta frecuencia de estos hallazgos en los pacientes con colangitis y el engrosamiento de las paredes de la vía biliar fue el más común, en el 92,6% de los casos, seguido por la presencia de halo pericolangítico en el 59,3% de los casos y contenido ductal en el 66,7% de los casos. Igualmente se encontró asociación ascendente de las frecuencias con grado de severidad de la colangitis. Resulta recomendable realizar estudios con un mayor poder estadístico que permitan validar nuestros resultados para una futura inclusión de la EUS en el algoritmo diagnóstico de las guías de práctica clínica en colangitis aguda.
Esofagograma: imágenes que valen mas que mil palabras
Authors: Borráez Segura Bernardo Alfonso , Gómez Monroy Daniel Fernando , Meza Julián , OLiveros Wilches Ricardo , Pinilla Morales Raúl Eduardo , Prieto Ortíz Robin Germán , Andolfi Ciro , Ramírez Mauricio
Published: September 2017

El estudio de las enfermedades esofágicas requiere de múltiples exámenes diagnósticos, ya que ninguno, por sí solo, provee total información sobre funcionalidad y la anatomía del tracto digestivo superior. Para los cirujanos generales y gastrointestinales, el esofagograma constituye una herramienta esencial que, además de sugerir un diagnóstico, ofrece una idea de la anatomía del órgano y nos permite esbozar un mapa de fácil evaluación (sin la necesidad de un radiólogo), para establecer o definir un plan quirúrgico. El objetivo del presente artículo es mostrar al lector la utilidad del esofagograma en centros de referencia en el estudio y el tratamiento de las enfermedades esofágicas, así como su representación en algunas enfermedades frecuentes
Apendicitis atípica diagnosticada durante una colonoscopia: Reporte de caso clínico
Authors: Angel Pinzón Alberto , Chavarro Orjuela Oliver , Cardona Ramírez Jhojan Danilo
Published: September 2017

Se presenta el caso clínico de una apendicitis atípica diagnosticada durante una colonoscopia en un paciente masculino de 85 años, en estudio por síndrome anémico y hospitalizado por un cuadro de infección neumónica en la Clínica Versalles de Manizales, Caldas. Durante la exploración del ciego, se observa un orificio apendicular prominente, con salida de material purulento hacia la luz del colon. La apendicitis atípica es un cuadro que puede presentarse en ancianos y, en ocasiones, se diagnostica durante una colonoscopia. El manejo de estos pacientes es poco claro y suele ser determinado por el médico tratante.
The Effect of Locus of Control, Time Budget Pressure, and Professional Commitment on Dysfunctional Audit Behaviour
Authors: Mangiwa Christian , Bandang Agus , Ridwan Hamka , Ashari Muhammad , Lobo Maxyanus Taruk
Published: September 2017

This study aims to determine the effect of locus of control, time budget pressure, and professional commitment on dysfunctional audit behaviour. The data used in this research is the primary data. Data was collected by using a survey method by distributing questionnaires to the auditors of Representative Supreme Audit Board in South Sulawesi Province. The method of analysis that was used to test the hypothesis is multiple linear regression with software Statistical Package for Social Science (SPSS) version 23. The analysis is based on data from 55 respondents who have completed all the statements and questionnaires. The results of this study show that (1) external locus of control and time budget pressure has a positive effect on dysfunctional audit behaviour and (2) professional commitment has a negative effect on dysfunctional audit behaviour.
Prophylactic use of the Angel® Catheter in a patient with paraneoplastic syndrome scheduled for surgical tumor resection: A case report and literature review
Authors: Stamenkovic Dusica , Neskovic Vojislava , Marjanovic Ivan , Tomic Aleksandar , Rusovic Sinisa , Marinkovic Vlastimir , Bancevic Vladimir , Karanikolas Menelaos
Published: September 2017

Introductio. The Angel? catheter (BiO2 Medical Inc, San Antonio, Texas, USA) is a novel device that combines a triple lumen central venous catheter with an inferior vena cava filter for prevention of pulmonary embolism (IVC filtercatheter). Case report. We present the case of a 53- yearold male patient with renal carcinoma and a history of recent deep venous thrombosis (DVT) on oral anticoagulation who was scheduled to undergo open radical nephrectomy. Because of concerns about the risks from documented pre-existing DVT, we decided to insert the Angel? catheter preoperatively in order to have central venous access during surgery and also to reduce the risk of perioperative pulmonary embolism. On the first postoperative day, active gastric bleeding was detected and nadroparine was stopped. Before removal of the Angel? catheter, a pre-removal cavagram revealed large thrombus mass in the catheter filter. Because of the presence of the thrombus mass, the catheter was removed surgically, after a permanent vena cava filter was inserted. Conclusion. This case suggests that the use of the Angel? IVC filter/3-lumen central catheter combination could be a reasonable option for pulmonary embolism prophylaxis in the patients at a high risk for DVT, such as the patients with malignant disease, paraneoplastic syndrome and chemotherapy who need to undergo surgery.
Urinary transferrin as an early biomarker of diabetic nephropathy
Authors: Terzic Brankica , Stanojevic Ivan , Radojicic Zoran , Resan Mirko , Petrovic Dejan , Maksic Djoko , Djekic Jelena , Ristic Petar , Petrovic Milica , Mijuskovic Mirjana
Published: September 2017

Background/Aim. Diabetic nephropathy is one of the leading cause of chronic kidney disease and end-stage renal disease. It occurs in 20%?40% of patients with diabetes mellitus and microalbuminuria is still considered as the first sign of diabetic nephropathy. Low sensitivity and specificity of microalbuminuria lead to more sensitive biomarkers that may be used to detect diabetic nephropathy at an earlier stage with a higher accuracy. This study was carried out to determine whether urinary transferrin can serve as an indicator of diabetic nephropathy. Methods. Our study included 80 type 2 diabetic patients who were classified into two groups: group 1 ? normoalbuminuric patients (albumin excretion up to 30 mg/d); group 2 ? microalbuminuric patients (albumin excretion from 30?300 mg/d), and 10 healthy controls. All patients were older than 18, having the diabetic disease more than one year, glomerular filtration rate more than 60 mL/min/1.73 m2. Serum creatinine, glycosylated hemoglobin (HbA1c), and concentration of transferrin in the 24 h urine samples as well as in spot urine were measured using a highly sensitive one-step sandwich enzyme immunoassay kit. Results. Urinary transferrin was significantly higher in the microalbuminuric patients than in the normoalbuminuric ones and healthy control subjects. When comparing these goups according to the urinary transferrin concentration, we found a statistically significant positive correlation r = 0.584 (p < 0.001). There was no correlation between level of urinary transferrin and glycoregulation, and no correlation was found between transferrin and duration of diabetes. Conclusions. The results from this study provide the evidence that the urinary transferrin levels could be used as an early marker of diabetic nephropathy.
Budgeting Audit Time: Effects of Audit Step Frame and Verifiability
Authors: Maksymov Eldar M. , Nelson Mark W. , Kinney William R
Published: September 2017

Auditors must ensure that their audit plans budget sufficient time for key audit steps. Research has shown that insufficient audit time budgets can be detrimental to audit quality. We examine whether framing audit steps negatively (e.g., assess whether management's assumptions are not appropriate) increases time budgets—particularly for steps in which the auditor perceives that performance quality is less verifiable, and thus most at risk of being performed with low quality. First, we report the results of analyses indicating that, in practice, audit steps are predominantly framed positively, potentially resulting in smaller time budgets. We then report the results of an experiment in which 50 experienced audit managers budget time for an audit program that tests a Level-3 fair-value estimate. Prior research and Public Company Accounting Oversight Board (PCAOB) inspections indicate that this is a challenging audit area, vulnerable to allegations of low audit quality. The results support our predictions and suggest that reframing audit steps negatively would increase audit time budgets—an audit quality indicator—particularly for less-verifiable steps.
Tres notas al "Quijote"
Authors: Avalle-Arce Juan Bautista
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
Latinismos arrusticados en el sayagués
Authors: Weber de Kurlat Frida
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
"Soy quien soy"
Authors: Spitzer Leo
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
La Iberia en el sustrato étnico-lingüístico del Mediterráneo occidental, I. Los nombres del alcornoque; II. "Cuniculus"; III. "Plumbum", "galena", "minium"
Authors: Bertoldi Vittorio
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
Una nueva pieza en "títulos de comedias"
Authors: Avalle-Arce Juan Bautista
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
Música, instrumentos y danzas en las obras de Cervantes (I)
Authors: Salazar Adolfo
Published: September 2017

En este número no se incluyeron resúmenes ni palabras clave.
Estudios cervantinos recientes (1937-1947). Reseña
Authors: Fichter William L.
Published: September 2017

Estudios cervantinos recientes
Julio Caro Baroja, Materiales para una historia de la lengua vasca en su relación con la latina. Publ. por la Universidad de Salamanca, Madrid, 1945, 238 págs.
Authors: Gili Gaya Samuel
Published: September 2017

Se reseñó el libro: Materiales para una historia de la lengua vasca en su relación con la latina.
Fernando de Herrera, Rimas inéditas. Editadas por José Manuel Blecua. Madrid, 1948, 254 págs.
Authors: Gili Gaya Samuel
Published: September 2017

Se reseñó el libro: Rimas inéditas. Editadas por José Manuel Blecua.
Phytosome Drug Delivery of Natural Products: A Promising Technique for Enhancing Bioavailability
Authors: Anjana Rani , Sunil Kumar , Hitender Sharma , K. Khar R.
Published: September 2017

The phytosome technology was developed by Indena markedly enhancing the bioavailability of selected phytomedicines, by incorporating phospholipids into standardized plant extract, which improve their absorption and utilization. Phytosome are advanced form of herbal extract that shows better absorption profile than conventional herbal extract. The present review focus on the preparation and characterization techniques of phytosomes, merits and various landmarks in the field of phytosomes.
Olmesartan Medoxomil-Loaded Self-Nanoemulsifying Drug Delivery Systems: Design, In-Vitro Characterization, and Pharmacokinetic Assessments in Rabbits Via LC-MS/MS
Authors: A. El-Assal M. I. , A. El-Gendy M. , I. Tadros M. , N. El-Gazayerly O.
Published: September 2017

Olmesartan medoxomil (OLM) is a lipophilic (log P = 4.31) antihypertensive drug suffering from limited oral bioavailability in humans (26%) due to its low aqueous solubility, uncontrolled enzymatic conversion to the active metabolite (olmesartan; OL) and efflux by drug resistance pumps. Surmounting such limitations via incorporation of OLM into self-nanoemulsifying drug delivery systems (SNEDDS). Based on OLM-equilibrium solubility studies in various oils, surfactants and co-surfactants, Capmul® MCM, Tween® 20, Cremophor® EL and polyethylene glycol-400 (PEG) were combined in different ratios to plot ternary phase diagrams. OLM-loaded SENDDS were developed and evaluated for particle size, polydispersity index (PDI), zeta potential, self-emulsification time, morphology, drug released percentages after 5-min (Q5min%), 1-hour (Q1h%) and dissolution efficiency percentages (DE1h%). The OL pharmacokinetics from SNEDDS (F6) and Benicar® tablets were evaluated (LC-MS/MS) in rabbits. Spherical OLM-loaded SNEDDS were developed. The best-achieved SNEDDS (F6) showed short emulsification time (13 s), fine droplet size (60.00 nm), low PDI (0.25), negative zeta potential (-14.4 mV), promising dissolution parameters; Q5min% (29.78%), Q1h% (66.69%) and DE1h%(47.96%) and enhanced in vivo absorption characteristics; shorter Tmax, higher Cmax and larger AUC(0−48h; suggesting its potential for the enhancement of the oral absorption of practically insoluble drugs; like OLM.
Bioactive Compounds Investigation From Methanol Bark Extract of Pterocarpus marsupium Using GC-MS Analysis
Authors: Hugar Aruna L. , Kanjikar Amarvani P. , Londonkar Ramesh L.
Published: September 2017

Introduction: Medicinal plants still represent untapped sources of novel compounds with potential therapeutic effects for mitigating human maladies.Pterocarpus marsupium, commonly known as Bijasal, is a well-known drug in ayurvedic system of medicine. Materials and methods: The dried bark powder of P.marsupium was extracted by Soxhlet with methanol and analyzed by gas chromatography, while the mass spectra data of the compounds found in the extract was matched with the data available at National Institute of Standards and Technology (NIST) library. Results: The results of the GC-MS analysis provide different peaksdetermining the presence of 10 major phytocomponents, that are 1-Penten-3-one,1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-; Geranyl isovalerate; 2-Pentadecanone,6, 10, 14-trimethyl;Cyclopropaneoctanal, 2-octyl-; Octadecanoic acid;10-Octadecanoic acid, methyl ester; Heptadecanoic acid, 16-methyl,-methyl ester; Phytol; 4,8,12,16-Tetramethyl heptadecan-4-olide; Dasycarpidan-1-methanol, acetate with different therapeutic activities. Conclusion: The presence of these bioactive compounds justifies that the Pterocarpus marsupiumcan offer a base for using this compound as herbal alternative for the synthesis and development of new drug to treat various infectious diseases. However, isolation of individual phytochemical constituents might be useful to formulate a new novel drug.
Adsorption of Cr(Vi) Ion from Aqueous Solutions by Solid Waste of Potato Peels
Authors: Mohammed Nidhal M.Sh. , Mohammad Salim Haydar A.
Published: September 2017

Pollution of wastewater with heavy metal has always been a serious problem to the environment. Chromium is considered one of the most noxious heavy metals. Adsorption is now reorganized as an alternative technology of defence for chromium removal due to local availability, technical efficiency and cost effectiveness. Potato peel powder can be used as a low cost biosorbent to remove hexavalent chromium from aqueous solutions under various experimental conditions. Different parameters including equilibrium contact time, initial metal ion concentration, potato peel dose, pH and temperature were studied through a number of batch sorption experiments. Both the Langmuir and Freundlich were found to fit the adsorption isotherm of Cr (VI) ion onto potato peel. The Langmuir adsorption capacity was found to be 1.97 mg/g while Freundlich constants including Kf and n were 1.57 and 2.5, respectively. The adsorption kinetic was found to be more fit with the pseudo-first order model. This study showed a high efficiency of potato peel for the biosorption of Cr (VI) ion from aqueous solutions.
Los periodistas latinoamericanos en el siglo XXI: más allá del debate de la posverdad
Authors: Amado Adriana
Published: September 2017

La complejidad de factores que atraviesan los periodistas en los distintos países obliga a repensar la definición de la profesión que maneja habitualmente la discusión pública, basada muchas veces en modelos teóricos abstractos sin considerar los condicionantes reales de las prácticas periodísticas. Una encuesta global aporta datos para describir el periodismo de la región, una profesión que perdió la exclusividad de la producción de la información y que quedó en el medio de disputas de intereses que lo superan. Se trata, pues, de ampliar el debate para repensar el lugar del periodista en el relato informativo contemporáneo, más allá de conceptos coyunturales como el de la posverdad.
Genetic diversity and population structure of the African catfish, Clarias gariepinus (Burchell, 1822) in Kenya: implication for conservation and aquaculture
Authors: Barasa James E. , Mdyogolo Sinebongo , Abila Romulus , Grobler Johannes Paul , Skilton Robert A. , Bindeman Hesmari , Njahira Moses Ndotono , Chemoiwa Emily J. , Dangasuk Otto G. , Kaunda-Arara Boaz , Verheyen Erik
Published: September 2017

African catfish, Clarias gariepinus, is an important species in aquaculture and fisheries in Kenya. Mitochondrial D-loop control region was used to determine genetic variation and population structure in samples of C. gariepinus from 10 sites including five natural populations (Lakes Victoria (LVG), Kanyaboli (LKG), Turkana (LTA), Baringo (LBA) and Jipe (LJP), and five farms (Sangoro Aquaculture Center (SAN), Sagana Aquaculture Centre (SAG), University of Eldoret Fish Farm (UoE), Kibos Fish Farm (KIB), and Wakhungu Fish Farm (WKU)) in Kenya. Similarly, samples from eight localities (four natural populations: LVG/LKG, LTA, LBA, and four farmed: SAN, SAG, KIB, UoE) were genotyped using six microsatellite DNA loci. For the D-loop control region, samples from natural sites exhibited higher numbers of haplotypes and haplotype diversities compared to farmed samples, and 88.2% of haplotypes were private. All except LJP and LTA shared haplotypes, and the highest number of shared haplotypes (8) was detected in KIB. The 68 haplotypes we found in 268 individuals grouped into five phylogenetic clades: LVG/LKG, LTA, LBA, LJP and SAG. Haplotypes of farmed C. gariepinus mostly have haplotypes typical of LVG/LKG, and some shared haplotypes of the LBA population. Microsatellite analysis showed farmed samples have higher numbers of alleles than natural samples, but higher observed and expected heterozygosity levels were found in samples of natural populations. Fifteen pair-wise comparisons had significantly different FST values. All samples were in Hardy-Weinberg equilibrium. Samples from the eight localities grouped into four genetic clusters (LVG/LKG, LTA, LBA and SAG), indicating genetically distinct populations, which should be considered for aquaculture and conservation.
Solution of Two-Echelon Facility Location Problems by Approximation Methods
Authors: Jahangiriesmaili Mahyar , Bahrami Sina , Roorda Matthew J.
Published: September 2017

The two-echelon delivery structure is a strategy that can be implemented in urban areas to lower delivery costs by reducing the movement of heavy goods vehicles. In a two-echelon delivery structure, large trucks deliver shipments from a consolidation center to several terminals, where packages are transferred to smaller trucks for last-mile deliveries. This paper formulates a model that solves the two-echelon delivery structure by the use of approximation techniques. Several potential terminal locations and demand areas were identified, and the optimal number and locations of the terminals were examined, as the model evaluated the most cost-effective routes between the consolidation center, potential terminals, and demand areas. Downtown Toronto, Ontario, Canada, was chosen as the case study area to assess the model, and a cost analysis of the number and locations of the terminals was performed. The experiments showed that the number and the locations of the terminals were greatly influenced by the opening cost of the terminals and the transportation cost of the delivery trucks. It was also discovered that the likelihood of selection of terminals that were positioned near both the consolidation center and the center of the service area was higher than the likelihood of selection of terminals at any other location.
Proposed Method for Measuring Customer Orientation of Companies in Freight Transport Sector
Authors: Mancera Albert , Klaas Thorsten , Weidmann Ulrich , Nash Andrew
Published: September 2017

The freight transport industry is growing rapidly. There is great interest in improving processes and operations to make them more efficient and customer friendly. Freight transport research traditionally focuses on demand modeling, mode choice, and operational optimization. In contrast, this paper addresses a new field: development of a customer-oriented measurement system for freight and logistics companies. The measurement system was developed as part of research carried out for the Swiss National Railways Cargo Division and is based on professional expertise and data from stakeholders in all parts of the logistics chain. The proposed method is an indicator-based system built on a theoretical foundation, informed with the help of a workshop with experts, and validated with real-world data. The method can be used to measure the customer focus of logistics service providers over time and thus enable them to improve and benchmark a pool of logistics companies. The proposed method can also be customized to evaluate other specific customer needs by adjusting weights and indicators within its computational structure.
Modal Diversion Estimates
Authors: Zietlow Benjamin R. E. , Perry Ernest B. , Adams Teresa M. , Sivappha Thirunavukkarasu , Walljasper Soren
Published: September 2017

This research outlined and demonstrated an approach and methodology for assessing domestic truck traffic suitable for diversion to intermodal truck to rail shipping. The research was spurred by the following factors: transportation-related findings from the Wisconsin Economic Development Corporation's Wisconsin Economic Future Study: Statewide and Regional Analysis; a general interest in intermodal diversion from federal, state, and local transportation agencies (to alleviate roadway congestion, reduce road deterioration, and reduce transportation emissions and pollutants); and seemingly constant commentary from the state's private-sector freight stakeholders seeking increased inter-modal services. Estimates of diverted loads from trucking to truck-to-rail intermodal vary, depending on the associated cost savings, the commodity being shipped, and the distance between origin and destination. Model results suggest that nonmonetary incentives would be necessary for large volumes of freight to divert.
Discrete Choice Modeling of Freight Outsourcing Decisions of Canadian Manufacturers
Authors: Mostafa Toka S. , Roorda Matthew J.
Published: September 2017

Behavioral freight transportation modeling is an approach to enhance the quality of freight and logistics policy assessments. Outsourcing of freight activities is one of the essential decisions that firms make. Such decisions are influenced by factors such as economic conditions, competition, the industry, firm strategies, and firm characteristics. In this paper, the authors introduce a set of discrete choice models—binary and multinomial logit—that quantify the effect of some of these factors on outsourcing of the freight-related activities of goods production and logistics for Canadian manufacturers. The models were estimated with the use of data from the Survey of Innovation and Business Strategy obtained from Statistics Canada. The models consider firm characteristics (e.g., employment, number of products or services, and supplier locations), economic conditions, and local and international competition. The models also show the influence of the use of innovation and advanced technologies and measure the impact of government support programs for businesses (e.g., government grants) on outsourcing decisions. Models that explain international freight outsourcing are also presented. Model results highlight that freight outsourcing culture differs from one industry to another. Firms that use government training programs are more likely to outsource freight operations locally, whereas those that use government grants outsource their freight activities internationally. Model validation indicated acceptable predictive capabilities. Simplified models that were based on industry classification, location, and firm size were estimated and are to be used for future microsimulation purposes.
Optimizing and Modeling Tollway Operations Using Microsimulation: Case Study Sanand Toll Plaza, Ahmedabad, Gujarat, India
Authors: Bains Manraj Singh , Arkatkar Shriniwas S. , Anbumani K. S. , Subramaniam Siva
Published: September 2017

This study aimed to develop a microsimulation model for optimizing toll plaza operations in relation to operational cost and level of service for users. A well-calibrated and validated simulation model was developed in PTV Vissim, and several scenarios were simulated to test their efficacy at improving toll plaza operations. Data collected included classified entry traffic volume at the toll plaza, service time for different payment categories, percentage of lane utilization, and travel time while crossing the toll plaza. For modeling lane selection for vehicles, the PTV Vissim component object model application programming interface—which enables dynamic route choice—was used. From the results it was observed that the simulation model accurately represented the current operations at the toll plaza. Scenarios, such as implementing a number plate recognition technology and segregating lanes for different vehicle types to improve the level of service, were evaluated with the simulation model.
Car Drivers’ Experienced Level of Service on Freeways
Authors: Jensen Søren Underlien
Published: September 2017

The Danish Road Directorate sponsored a study to develop methods for quantifying car drivers’ experienced level of service on freeways. The results provide a measure of how well freeways accommodate car travel. To determine how traffic operations, geometric conditions, and other variables affect car drivers’ satisfaction, 188 randomly selected respondents were shown 80 video clips of roadway segments filmed from a driven passenger car. Video clips consisted of high-resolution video filmed through a windshield, side windows including exterior mirrors, and a rear window. Video clips also included a GPS-based speedometer. Respondents rated video clips on a six-point scale ranging from very satisfied to very dissatisfied. The result was 7,497 usable ratings. Four hundred to 450 variables described respondents’ answers to six background questions and the video clips, that is, roadway segment geometries, traffic operations, surroundings, weather, and so forth. Car driver satisfaction models were developed with cumulative logit regression and ordinary generalized linear modeling. The six presented models included three to 10 variables, which related significantly ( p ≤ .05) to satisfaction ratings. These variables were average speed, speed limit, width of hard shoulder, number of entries and other merge areas per mile, number of exits and other diverge areas per mile, flow of long vehicles per lane per hour, direction of sunlight, driver age, type of driver’s license, and driver yearly mileage. Models returned percentage splits of the six levels of satisfaction or average satisfaction. These splits or averages were transformed into a level of service.