bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Post-Mortem Changes in Human Microbiome
Authors:   Oles Honchar Dnipro National University. 72, Gagarin Avenue, Dnipro city 49010, Ukraine, Pohorielova A. M. , Sokolova I. Ye. , Gavrilyuk V. G. , Vinogradova K. O. , Sklyar T. V.
Published: February 2021

The article presents the results of the thanatomicrobiome study from 18 corpses. Biomaterial for the study was selected in the Department of forensic examination of corpses in "Dnipropetrovsk Regional Bureau of Forensic Medicine" of the Dnipropetrovsk Regional Council during September 2020. Microbiological investigation was conducted at the Department of Microbiology, Virology and Biotechnology of Oles Honchar Dnipro National University. The purpose of the study was to determine the composition of the human thanatomicrobiome and its characteristic marker microorganisms for using it in forensics. Therefore, the task of this research was to study the characteristics of the postmortem microflora depending on age, sex, causes of death, post-mortem time of objects. Material and methods. To solve the assigned tasks such methods were used: microbiological, biochemical, physicochemical, statistical. Identification of microorganisms was conducted with using of selective and differential-diagnostic nutrient medium. Results and discussion. Among the isolated microorganisms in the thanatomicrobiome, the most common were represented by bacteria of genera Staphylococcus, Streptococcus, Enterococcus and family Enterobacteriaceae. Determining of thanatomicrobiome characteristics depending on sex was shown that the highest frequency of isolation for most bacterial species was found in men. The highest frequency of detection of microorganisms was observed on the first day after death. Staphylococcus spp. and Streptococcus spp. were presented in the postmortem microflora during all three days of observation, but frequency of their detection after 48 hours was significantly reduced. Salmonella spp. and Pseudomonas spp. were detected in the thanatomicrobiome only on the third day after death. In the study of the dependence of the microbiota on the causes of death, it was found that the frequency of Streptococcus spp. was higher in subjects who died from hanging, and bacteria of the genera Staphylococcus, Enterococcus, and Klebsiella were predominantly isolated from those who died of cardiovascular disorders. Bacteria of genera Staphylococcus, Streptococcus, Enterococcus, which together make up the vast majority of microorganisms was 64% in the oral cavity and 82% in the armpits should be considered as biomarkers of thanatomicrobiome. An indicative biomarker is also the increase of certain species of enterobacteria in the process of corpses destruction. Yeast and clostridia were specific markers of oral thanatomicrobiome. Conclusion. The composition of the thanatomicrobiome and its features may provide additional information about the conditions of death
Effect of Mindi Leaf Powder (Melia azedarach L) on Mortality of Anopheles aconitus Instar III Larvae
Authors: Atmaja Tajudin Rahmat Surya , Ratnaningrum Kanti , Tursinawati Yanuarita
Published: February 2021

Background: Malaria is a disease caused by Plasmodium parasite infection wwhich is transmitted through bite of an Anopheles mosquito. Efforts to control malaria can be carried out in various ways, starting from treatment, prevention, to breaking the transmission chain through vectors, both mosquitoes and larvae. Mindi tree contains Azadiractin compounds which are larvicides. Study aims to determine effect of mindi leaf powder (Melia azedarach L) on mortality of Anopheles aconitus instar III larvae.Methods: A true experimental study with a post test only control group design, the object of research was Anopheles aconitus Instar III larvae. The research was conducted at Laboratory of Parasitology, Faculty of Medicine, Universitas Islam Sultan Agung, Semarang. 20 larvae / 100 ml were used. Air temperature and water pH were controlled during observation. Assessment by counting number of mortality larvae and the number of live larvae from each treatment was compared to the control. The data obtained were analyzed by the Kruskal-Wallis statistical test. The LD50 and LD90 were analyzed using Probit analysis.Results: The dose of 0.2 g/100 ml was the minimum dose that killed 100% of larvae of Anopheles aconitus (p = 0.01). In the probit test, LD50 was 0.01 g/100 ml of aquades, while LD90 was 0.06 gram/ 100 ml of aquades.Conclusion: Dose can served as larvicidal (LD90 )was 0.06 g/100 ml of aquades., while LD50 was 0.01 g/100 ml of aquades.
Central and Peripheral Obesity on Severity Knee Osteoarthritis
Authors: Efendi Refangga Lova Nusantara , Wahab Zulfachmi , Setiawan M. Riza
Published: February 2021

Background: Obesity can affect severity of knee osteoarthritis sufferers. Several studies have examined relationship between obesity and osteoarthritis, but no one has examined the different types of obesity on osteoarthritis, therefore, researchers wanted to know differences of central and peripheral obesity on severity osteoarthritis.Methods: A retrospective studi, with cross-sectional, simple random sampling method, conducted between 1 August 2014 and 30 September 2014 in Semarang City. Samples people > 50 years old. Data were analyzed by rank Spearman and Anova correlation.Results: In this study, 45.7% (n = 32) reported severe osteoarthritis. The results of the statistical test obtained p1 = 0,000 (reject Ho). The correlation coefficient (r) is 0.857 (strong), and the linear pattern is positive. The coefficient of determination (r2) is obtained (0.857) 2 = 0.73 = 73%. And 37.1% (N = 26) reported being obese. p2 = 0.043 (reject Ho). The mean deviation (MD) was 0.048 (not significant) between central obesity and peripheral obesity.Conclusion: Obesity affects severity of knee osteoarthritis. The greater body mass index, greater severity of knee osteoarthritis. 73% of severity of knee osteoarthritis is influenced by obesity, but there is no significant effect between central and peripheral obesity on the occurrence of knee osteoarthritis.
DAFTAR ISI MAGNA MEDICA VOL 7 NO 1 PEBRUARI 2020
Authors: Anas Muhammad
Published: February 2021

DAFTAR ISI
Estimates of mortality attributable to COVID-19: a statistical model for monitoring COVID-19 and seasonal influenza, Denmark, spring 2020
Authors: Nielsen Jens , Rod Naja Hulvej , Vestergaard Lasse S , Lange Theis
Published: February 2021

Background

Timely monitoring of COVID-19 impact on mortality is critical for rapid risk assessment and public health action.

Aim

Building upon well-established models to estimate influenza-related mortality, we propose a new statistical Attributable Mortality Model (AttMOMO), which estimates mortality attributable to one or more pathogens simultaneously (e.g. SARS-CoV-2 and seasonal influenza viruses), while adjusting for seasonality and excess temperatures.

Methods

Data from Nationwide Danish registers from 2014-week(W)W27 to 2020-W22 were used to exemplify utilities of the model, and to estimate COVID-19 and influenza attributable mortality from 2019-W40 to 2020-W20.

Results

SARS-CoV-2 was registered in Denmark from 2020-W09. Mortality attributable to COVID-19 in Denmark increased steeply, and peaked in 2020-W14. As preventive measures and national lockdown were implemented from 2020-W12, the attributable mortality started declining within a few weeks. Mortality attributable to COVID-19 from 2020-W09 to 2020-W20 was estimated to 16.2 (95% confidence interval (CI): 12.0 to 20.4) per 100,000 person-years. The 2019/20 influenza season was mild with few deaths attributable to influenza, 3.2 (95% CI: 1.1 to 5.4) per 100,000 person-years.

Conclusion

AttMOMO estimates mortality attributable to several pathogens simultaneously, providing a fuller picture of mortality by COVID-19 during the pandemic in the context of other seasonal diseases and mortality patterns. Using Danish data, we show that the model accurately estimates mortality attributable to COVID-19 and influenza, respectively. We propose using standardised indicators for pathogen circulation in the population, to make estimates comparable between countries and applicable for timely monitoring.
“The Life Grew So Difficult”: Reaction of the Leningrad Citizens to Postwar Loan Campaigns in the Party Organizations Summaries of Information
Authors:   St. Petersburg State University, St. Petersburg, Russian Federation, Novikov Maxim D.
Published: February 2021

The article draws on the AUCP (b) obkoms summaries of information on conducting loan campaigns to analyze the attitude of Soviet citizens to state financial policy. Since access to personal information is restricted, thus making it difficult to study social aspects of state policy, the author has turned to the summaries documents and thus introduced them into scientific use. The object of the study is government loans during the forth five-year plan (1946-1950) and subscription to these in Leningrad. Obkom summaries contain both statistical data and information on the population’s response to the subscription. The analysis shows that people understood of its goals, which translated into their positive responses. Negative assessments sprang mainly from domestic problems, not from overt criticism of the state. The facts are conveyed in a peculiar way. Summaries were in many ways a means of confirming the agitators’ and propagandists’ success at the grassroots level, and therefore the positive attitudes towards loans prevailed. Negative reactions were describes as “isolated cases” to work case by case. An expression “hard to live” permeates the analyzed materials, though only rarely these “hardships” were real. The phrase explained people’s reluctance to participate in the subscription. Using these documents in historical research is essential to understanding the management of information in the party organizations. The combination of positive and negative reactions in the reports makes it possible to study the public opinion of the postwar Soviet people in depth. The data obtained from the reports fills out the history of postwar loan campaigns with factual material and add to social, political history, and history of the everyday life in the postwar USSR.
L. D. Trotsky’s “The Lessons of October” and the Struggles at the Highest Level: Viewpoint of the Population in 1920s
Authors:   Bryansk State University. Acad. I. G. Petrovsky, Bryansk, Russian Federation, Bryantsev Michail V.
Published: February 2021

The article analyses the aftermath of the publication of Trotsky's “The Lessons of October” in autumn of 1924, which produced much controversy in the camp of his opponents. Kamenev, Stalin, and his others smote Trotsky and posed the question “Leninism or Trotskyism?” to antithesize Lenin and Trotsky. The controversy was in the focus of attention of Soviet citizens, who showed “great interest” in this “literary discussion.” The issue remained center-stage in late 1924 - early 1925. The analysis of information materials demonstrates controversial attitudes of the population to the struggle. Many championed Trotsky. Having no way to find out more about Trotsky's views and mistrusting official publications, people often gave preference to rumors, which reflected not facts, but their wishes. Many saw in Trotsky their defender from the arbitrary rule, who acted in the interest of the people and suffered for his views. Many, party members also, demanded to allow Trotsky to express his opinions outside the framework of propaganda. At the same time, the “The Lessons of October” fed the negative image of Trotsky, already in formation. Quite noticeable role was played by the official propaganda trying to paint Trotsky as a traitor to the interests of the Soviet state. Not understanding the mechanism of the internal conflicts which after Lenin's death were tearing the RCP(B) apart, the population was swept by the Central Committee propaganda. Party propagandists cast Trotsky as a detractor of the party and Lenin himself. The campaign launched against Trotsky and his “The Lessons of October” bore its fruit. The authorities presented Trotsky as a Menshevik and unscrupulous enemy of the Soviet power. Information materials of early 1925 show not only a slump in Trotsky’s popularity, but also a growing bias against him.
Finances of Soviet Latvia on the Eve of and during the Great Patriotic War: Materials from the Russian State Archive of Economy
Authors:   St. Petersburg State University, St. Petersburg, Russian Federation, Zotova Anastasia V.
Published: February 2021

The article provides an overview of documents of the Russian State Archive of Economy (RGAE), which reflect the dynamics of financial support for all aspects of life in the Latvian SSR from August 1940 to May 1945. These documents are stored in series 25–30 of fond 7733 “Ministry of Finance of the USSR. 1917-1991” and have not yet been studied by researchers. Series 25 and 26 contain rich data on financing of various branches of the Latvian economy, including those not developed in Latvia previously. The peculiarity of currency circulation in late 1940 ? early 1941 is described. There were two currencies in circulation in the Republic at the time: the lats and the rubles. The documents show that the central government policy did not seek to destroy private farms. On the contrary, the authorities provided Latvian peasants with loans on favorable terms to help the population to adapt to Soviet life. The documents inform that 50 machine-tractor stations were built in Soviet Latvia in a short period of time. These stations were exempt from taxes. Series 26 contains documents that provide data on plans for financing the social sphere in Latvia in 1941 to the extent of 50.8% of all expenses. This figure was significantly higher than in any other union republic. In the RGAE there are unique documents on the financing of Soviet Latvia during the Great Patriotic War. There are cost estimates that allow to study state expenditures on the functioning of the Soviet Latvian government in the period from 1942 to 1943. In series 29 and 30, there is much information on the transfer of funds for the restoration of the destroyed economy and social sphere of the Latvian SSR and on the priorities of financial security. In addition to the restoration of enterprises, institutions, and housing, significant funds were transferred to the implementation of new social projects: construction of higher educational institutions, technical schools, schools, libraries, museums, theaters, and cinemas.
El salario de los periodistas, el ancla a su participación en las redes de clientelismo mediático
Authors: Maldonado Pérez Patricia
Published: February 2021

La prioridad de los medios de comunicación a tener de cliente principal al poder político ha resultado para los periodistas en explotación laboral y sometimiento profesional. Los medio de comunicación pagan un mísero salario a los periodistas y/o los utilizan de vendedores de publicidad adicional. Sin embargo, de forma subyacente, transfieren a quienes ocupan cargos representativos en gobierno, poder para intervenir y controlar la información que se publica en los medios impresos. A partir los testimonios de periodistas de referencia del Estado de México se busca probar en este estudio que el nivel salarial de los periodistas es el gancho para su participación en las redes de clientelismo mediático que redundan en la expansión del poder político y control social desde el manejo informativo de los medios de comunicación. En ese objetivo, se atraen a Hallin y Mancini (2004), como soporte de análisis, desde su propuesta conceptual de profesionalización a la que se busca incorporar como indicador la posición salarial de los periodistas.
Predictores de las tendencias morales asociadas al uso de Facebook
Authors: Pérez Sánchez Rolando , Giusti Mora Gloriana , Soto Chavarría Karina
Published: February 2021

Este artículo es un aporte al estudio del procesamiento moral del uso de Facebook desde el punto de vista de la cognición social. La investigación tuvo por objetivo identificar algunos predictores de las tendencias morales de uso, específicamente aquellas denominadas por la investigación antecedente como hedonista y eudaimónica, de esta red social. El énfasis se concentró en la medición de las posibles asociaciones entre un tipo de comportamiento auto-presentativo y otro prosocial y la presencia de las tendencias hedonistas y eudaimónicas. Se recurrió a un cuestionario auto-aplicado, administrado a 122 estudiantes universitarios (62.5% mujeres y edad promedio 20.77, DT: 6.85). Los resultados mostraron una asociación negativa entre el comportamiento prosocial y las tendencias hedonistas, así como otra asociación positiva entre el comportamiento de uso prosocial y la tendencia moral eudaimónica. Se discuten estos resultados identificando sus alcances y señalando la necesidad de mayor investigación futura.
Aguilar Edwards, Andrea (coord.) (2016). Desafíos de la Inclusión y Procesos de Comunicación, México: Fontamara
Authors: Pérez Salazar Gabriel
Published: February 2021

La investigación que se hace en las Universidadesdebe responder a las necesidades más urgentes de la sociedad, en todos sus campos del conocimiento. Tal es el caso de Desafíos de la Inclusión y Procesos de Comunicación, obra colectiva coordinada por Andrea Aguilar Edwards(Universidad Autónoma de Coahuila), que reúne a autores de muy variadas instituciones como la Universidad Autónoma de la Ciudad de México, la Universidad Autónoma Metropolitana, el Instituto Politécnico Nacional, el Instituto Tecnológico y de Estudios Superiores de Monterrey, la Universidad Nacional Autónoma de México, la Benemérita Universidad Autónoma de Puebla y la Universidad de Guadalajara.
Percepciones de la interacción y la comunicación en el trabajo colaborativo con TIC, comparativa de los alumnos licenciatura en Comunicación y Periodismo y de la licenciatura en Desarrollo local de la Universidad Autónoma de Querétaro.
Authors: Rode Villa Carlos Alberto , Amezcua Vanesa Del Carmen , Guerrero Ramírez Sandra Luz
Published: February 2021

El objetivo del trabajo es conocer la manera en que se dan los procesos de comunicación y las herramientas digitales que utilizan los alumnos de la Licenciatura en Comunicación  y Periodismo  y de Desarrollo Local de la Universidad Autónoma de Querétaro en México, al trabajar colaborativamente. A través de dos grupos focales con alumnos de diferentes semestres; se investigó sobre dos dimensiones de la colaboración: la comunicación y el diálogo mediante el  uso de herramientas tecnológicas. Se encontró que existen dificultades al comunicarse y dialogar cuando trabajan de manera colaborativa, no saben hacerlo; y que las herramientas tecnológicas dificultan más este proceso. Por otro lado la falta de infraestructura en las zonas rurales hace complicado el uso de las tecnologías para colaborar lo que priva a algunos de esta experiencia. Con base en los resultados se concluye que las instituciones educativas deben apoyar la adopción de estrategias didácticas que permitan  desarrollar y evaluar habilidades colaborativas que generen un verdadero diálogo que fortalezca las actividades del aprendizaje colaborativo sin importar si se usan o no, las herramientas tecnológicas. Es importante el papel de las Universidades y el gobierno en la cobertura de la infraestructura para el uso de internet.
Nickel silicide formation with rapid thermal treatment in the heat balance mode
Authors: Pilipenko V. A. , Solovjov Ja. A. , Gaiduk P. I.
Published: February 2021

The formation of nickel silicide layers on (111)-Si substrates during rapid thermal annealing in the heat balance mode was studied by the Rutherford backscattering method, X-ray diffraction, transmission electron microscopy, and electrophysical measurements. Nickel films of about 70 nm thickness were deposited by magnetron sputtering at room temperature. The rapid thermal treatment was carried out in a heat balance mode by irradiating the substrates backside with a non-coherent light flux of quartz halogen lamps in the nitrogen medium for 7 seconds up to the temperature range of 200 to 550 °C. The redistribution of nickel and silicon atoms to monosilicide NiSi composition starts already at a temperature of 300 °С and almost ends at a temperature of 400 °С. In the same temperature range, the orthorhombic NiSi phase with an average grain size of about 0.05–0.1 μm is formed. At a rapid thermal treatment temperature of 300 °C, two phases of silicides (Ni2 Si and NiSi) are formed, while a thin layer of unreacted Ni is retained on the surface. This fact can be explained by the high heating rate at the initial annealing stage, at which the temperature conditions of the NiSi phase formation occur earlier than the entire Ni layer manages to turn into the Ni2 Si phase. The layers with a simultaneous presence of three phases are characterized by a high roughness of the silicide-silicon interface. The dependence of the specific resistivity of nickel silicide layers shows an increase to the values of 26–30 μOhm · cm in the range of rapid thermal treatment temperatures of 200–250 °C and a subsequent decrease to the values of about 15 μOhm · cm at a rapid thermal treatment temperature of 400 °C. This value of specific resistivity is characteristic of the high conductivity of the NiSi phase and correlates well with the results of structure studies.
Setting the functional properties of TiNi alloys during ion-plasma coating deposition process
Authors: Rubanik V. V. , Bahrets D. A. , Rubanik jr. V. V. , Urban V. I. , Uzhekina A. N. , Dorodeiko V. G.
Published: February 2021

The aim of the present work is to study the influence of the technological parameters of the ion-plasma treatment (IPT) on the functional properties of a TiNi shape memory alloy and its biocompatibility. The object of the study was the Ti–50.8 at. % Ni alloy, widely applied in medical devices. IPT was carried out by vacuum-arc evaporation of a titanium cathode at different values of the bias potential (0, –100, and –500 V), followed by TiN deposition. The functional properties of the TiNi alloy after IPT were investigated using differential scanning calorimetry. The biocompatible properties were evaluated using atomic emission spectrometry to measure a nickel concentration after one year holding TiN-coated TiNi samples in the 0.9 % NaCl solution. It has been determined that by setting the temperature regime of heating of Ti–50.8 at. % Ni alloy samples due to the technological parameters of the IPT process, it is possible to change the interval of realization of thermoelastic martensitic transformations, and, consequently, the temperature response of devices made of this alloy, i. e. to set the necessary functional properties. The comparative analysis of the characteristic temperatures after heat and ion-plasma treatments allow us to conclude that the proposed method for calculation of the TiNi substrate temperature is correct at IPT. The calculated temperature of the TiNi samples was ~275 °C at the zero potential, which is sufficient to shift the characteristic temperatures of the alloy. The substrate temperature during deposition was ~400 °C at a – 100 V bias and above 600 °C at a – 500 V bias, respectively. The Ni concentration in the model solution did not exceed 0.14 mg/l after one year holding, which indicates the high biocompatibility of the TiN-coated TiNi samples.
Molecular genetic characteristic of soft winter wheat samples in connection with breeding for lodging resistance
Authors: Sycheva Е. A. , Bondarevich E. B. , Solovey L. A. , Shimko V. E. , Hardzei S. I. , Satsyuk I. V. , Dubovets N. I.
Published: February 2021

The objective of the study was to analyze the genomic structure and allelic composition of the dwarfing Rht-B1, Rht-D1 and Rht8 genes in 37 varieties and breeding samples of soft winter wheat in connection with breeding for lodging resistance in the Republic of Belarus. The molecular cytogenetic marking (C-banding) and DNA typing of genotypes were used. As a result, the analysis of the chromosomal composition of the breeding material showed that 21 winter wheat samples are characterized by the standard karyotype with the genomic structure AABBDD (2n = 42). Five variants of translocations affecting the chromosomes 1B, 3B, 5B, 6B, and 7B were revealed in the karyotypes of the remaining samples. It was found that the chromosomes of the 2nd and 4th homologous groups, in which the main dwarfing genes (Rht-B1, Rht-D1, and Rht8) are localized, did not undergo structural changes. Genotyping showed that 45.9 % of the samples contain one of the dwarfing alleles (Rht-B1b, Rht-D1b, Rht8c) in their genotype. A combination of two commercially significant alleles (Rht-B1b and Rht8c) in the genotype were identified in one of the winter wheat samples. The genotype with a combination of the Rht-B1a, Rht-D1a and Rht8b alleles occurred with the highest frequency (37.8 %) in the analysed breeding material. The Rht-B1b, Rht-D1a, Rht8b; Rht-B1a, Rht-D1a, Rht8a genotypes showed the frequency of 16.2 %. The Rht-B1a, Rht-D1a, Rht8c; Rht-B1a, Rht-D1b, Rht8b; Rht-B1a, Rht-D1b, Rht8j genotypes were identified in 5.4 % of the samples; the Rht-B1a, Rht-D1b, Rht8а genotypes – in 8.1 % of the samples. The analysis of the plant height, taking into account the karyotyping and genotyping data showed that the targeted selection of the most efficient allelic combinations of dwarfing genes is important for the cultivation region. The studies carried out allow us to suggest that the selection by the overwintering level can contribute to the fixation of the Rht8b allele in the breeding material, which is apparently associated with better winter hardiness in the conditions of Belarus.
Methods of drug therapy for severe dry eye disease
Authors: Semak G. R.
Published: February 2021

Treatment of chronic dystrophic diseases of the ocular surface always requires concomitant correction of severe dry eye disease (DED). The purpose of this publication was to analyze the literature data illustrating the current trends in the development of drug therapy for severe dry eye disease of non-Shegren’s etiology.

The search for thematic publications was carried out in the PubMed database. The query “(dry-eye-disease AND treatment) NOT Sjögren” (filter: clinical trials, randomized controlled clinical trials, meta-analyzes) found 56 results since 2019.

The review included 11 publications describing the results of clinical studies of the effectiveness of drug methods in the treatment of severe DED.

In the treatment of severe DED, the prevailing direction of research is the relief of inflammation in the ocular surface tissues. Among the non-steroidal immunomodulatory drugs, the majority of studies were dedicated to cyclosporine, including its nanoemulsion form, diquafosol and bevacizumab. Their effectiveness and safety have been proven. In the Republic of Belarus, there is no unified approach to the management of patients with severe and comorbid DED. The main focus is on the activation of regenerative processes. Platelet rich plasma and subconjunctival administration of low molecular weight sodium hyaluronate demonstrated high efficiency.
Osteogenic and chondrogenic differentiation potential of mesenchymal stem cells obtained from the bone marrow and placenta
Authors: Zhernasechanka H. A. , Isaikina Ya. I. , Filipovich T. V. , Liakh E. G.
Published: February 2021

Mesenchymal stem cells (MSC) represent a perspective resource for cell biotechnology. However the question of chondrogenic and osteogenic capacity of MSC of different origin remains under study.

The aim of this study was to analyze the osteo-chondrogenic differentiation potential of MSC obtained from the bone marrow and placenta. The results of our studies have indicated that bone marrow-derived and placenta-derived MSC showed a chondrogenic potential in vitro after a chondrogenic induction with specific differentiation media. But for bone marrowderived MSC, the chondrogenic program was realized by expression of collagens (Coll2, Coll10), while in placenta-derived MSC cultures we found a progressive increase in COMP and Ver expression, so bone marrow-derived MSC is more preferable for use in cartilage tissue engineering. Regarding the results on alkaline phosphatase and alizarin red staining, bone marrowderived MSC showed a more significant osteogenic potential compared to placenta-derived MSC. Bone marrow-derived MSC in the composition of fibrin gel after osteogenic induction on the 14th day exhibited the activity of alkaline phosphatase, calcium depositions inside the cells and extracellular matrix, the increase in Sp7 and DMP expression.
Variability of anterolateral ligament on MRI images – lack of survey standardization or anatomical variants?
Authors: Kostrub O. O. , Кotiuk V. V. , Poliachenko Iu. V. , Gerasimenko M. A. , Blonskyi R. I. , Zasadnyuk I. A.
Published: February 2021

The anterolateral ligament is a rotational stabilizer of the knee joint. It is not always clear what we actually see on MRI in the area of anterolateral ligament (ALL).

The aim of the study was to evaluate the ALL variants on MRI images to summarize their common features and differences, and to try to find an explanation for the phenomenon of the ALL variability.

200 series of MRI images of knee joints were analyzed. The presence of the ALL, the number of its layers, the relation to the joint capsule, and other anatomical features were assessed.

The ALL was visualized on MRI at least partially in 88 % of cases. At least partially two-layer structure was detected in 68 % of all 200 MRI series. The wavy appearance of the certain portions of the anterolateral ligament was observed in some normal knee joints without a history of injuries.

Determined that the ALL is a separate anatomical element of the knee joint that has a variable, but in most cases two-layered, anatomical structure and can be detected on MRI in at least 88 % of cases. Axial sections help to identify ALL in complex cases and allow analyzing its anatomy, but adding little in the diagnosis of ALL injury.
Comprehensive prognosis of the consequences of secondary encephalitis in children
Authors: Niyozov Sh. T. , Djurabekova A. T. , Shomurodova D. S.
Published: February 2021

The paper presents the analysis of a study of children with secondary encephalitis, depending on the beginning of the acute period of which more than 6 months – a year has passed, the degree of neurological disorders, neuroimaging comparison and prediction depending on these indicators for timely neurometabolic therapy.

The purpose of our study was to study the complex prognosis of the consequences of secondary encephalitis in children. We observed 58 children with a consequence of encephalitis.

The total number of girls is 37 %, boys are 63 % which are the main group of patients. The control group of children are healthy identical in age 3‒10 years. All children admitted to the hospital underwent a standard examination, anamnesis, clinical and neurological examination, and neuroimaging (MRI, CT) studies. In addition, all children were determined on electromyography somatosensory evoked potential, including at admission, as well as at discharge.

The results of our study revealed that the prognosis only for clinical and neurological disorders gives 66.2 %, with the addition of neuroimaging assessment increased to 79 %, and meningial-somatosensory indicators still increases the forecast by 12 %, which is very important for timely neurometabolic therapy. In turn, the prognosis of the outcome of encephalitis in children will allow timely reduction of residual neurological manifestations.
WOMEN ARTISTS OF THE RENAISSANCE AND BAROQUE PERIOD IN ITALY: CULTURAL STUDIES DISCOURSE
Authors:   Kyiv National University of Culture and Arts, Ukraine, Goncharova Olena
Published: February 2021

The purpose of the monograph section. On the basis of anthropocentric approach to the analysis of visual self-presentations of Italian women artists of the Renaissance and Baroque period fill in the gaps that exist in domestic art history regarding the works of Plautilla Nelli, Sofonisba Anguissola, Lavinia Fontana, Marietta Robusti, Artemisia Gentileschi, Arcangela Paladini, Giovanna Garzoni, Elisabetta Sirani and the sculptor Properzia de’ Rossi. Theoretical basis. The principles and methods of philosophical and anthropological research in combination with biographical, historical, comparative, iconographic and figurative and stylistic methods were used in writing the monograph. The scientific novelty lies in the author's method of analyzing works of visual art from the point of view of anthropocentric approach, as well as in considering the creativity of women artists of Renaissance and Baroque period in Italy as their self-objectifications, which give rise to a new cultural reality. Conclusions. Creativity by Italian women artists Plautilla Nelli, Sofonisba Anguissola, Lavinia Fontana, Marietta Robusti, Artemisia Gentileschi, Arcangela Paladini, Giovanna Garzoni, Elisabetta Sirani and the sculptor Properzia de’ Rossi in diachronic view can be expanded. During 16th–17th centuries, several talented female painters and one female sculptor worked in Italian fine arts. Against the background of the cultural realities of the time, this phenomenon can be considered an indicator of paradigmatic changes in the public consciousness in relation to the social significance of talented women.
SCIENTIFIC AND TECHNICAL DEVELOPMENT OF SPACE INDUSTRY ENTERPRISES: NATIONAL AND INTERNATIONAL ASPECT
Authors:   Oles Honchar Dnipro National University, Ukraine, Dzhur Olga , Dzhur Yevhen ,   Oles Honchar Dnipro National University, Ukraine
Published: February 2021

The purpose of the article is to study and highlight promising areas of development of the space industry of Ukraine based on the potential of scientific and technical development, which was formed in at least years of space industry of Ukraine taking into account political, economic, social trends in Ukraine and the international economy. The methodological and informational basis of the study are the works of national and international statistical publications and reports, publications of consulting companies, information materials of space companies. To achieve this goal, a systems approach, correlation-regression analysis, methods of historical and logical approach, dialectical development, linguistic level of description of systems as the highest level of abstraction were used. Assessment of the success of modern world business and prospects of scientific and technological development of high-tech business, in particular space enterprises was analyzed using reports of such well-known publications as Fortune, McKinsey, SRG, MIT Technology, statistics of international organizations OECD, WIPO, World Bank, statistics State Statistics Service of Ukraine, State Space Agency of Ukraine. Value / originality. Comparative analysis of scientific and technical development of successful international economies, world aerospace business and scientific and technical development of Ukraine's economy and its space industry revealed weaknesses in the further development of space enterprises, propose measures to eliminate shortcomings, propose a scheme for selecting promising scientific and technical directions. industry and explore some correlation of important components of innovation development to the Global Competitiveness Index (GCI).
FORECASTING THE POTENTIAL OF THE ECONOMIC SYSTEM ON THE BASIS OF THE EXOGENIC GROWTH MODEL
Authors:   Vadym Hetman Kyiv National University of Economics, Ukraine, Poznyak Sergiy , Kolyada Yurii ,   Vadym Hetman Kyiv National University of Economics, Ukraine
Published: February 2021

The paper considers models of economic growth and the possibility of modifying a suitable model to find the potential for economic growth for the economy of society. The world global economy is studied, presented in terms of societies of the world, in monetary terms and the growth potential of gross domestic product in relation to capital, labor, technological progress, population and other macroeconomic indicators that affect it. Theoretical and methodological significance lies in the description of a fundamentally new method of modeling, which can be used to assess the potential of economic development, proving the dynamics of the coefficients of elasticity of production factors, and proving the hypothesis of declining economic growth. The developed model effectively estimates the potential for economic growth for any country and can be used as a basis for forecasting indicators of potential capital intensity of production and potential gross domestic product. Regarding the practical significance of the obtained results, it should be noted that all changes and numerical values are supported by real data and are a consequence of economic, political or social phenomena in the economy of the country under consideration. In the further research it is possible to develop this model, adding to it new variables which influence economic growth, to update methodology of finding of coefficients as a result of actions of economic agents, instead of only their exogenous influence on economy. The work has three main sections. The first section contains theoretical aspects of estimating the evolutionary economy in the one-dimensional case, it describes the basic theoretical information about the Solow model and other neoclassical and endogenous models of economic growth. The second section describes the possibilities of the Solow model for estimating economic growth potential and theoretical aspects and derives the mathematical basis for estimating economic growth potential. Also in this section describes the implementation of the mathematical base. The third section comments on the results of modeling, based on which detailed conclusions are formed, which summarize the economic, mathematical, analytical and technical work. The simulation results well illustrate the degree of use of economic potential, as well as the impact of capital, technological progress, investment, natural population movement on the efficiency of the economy in terms of many countries. The developed software (as a product of the digital economy) can be used to further improve the model, taking into account more factors.
ALTERNATIVE MEANS OF RESOLVING TAX DISPUTES IN UKRAINE: POSSIBLE WAYS OF IMPLEMENTATION
Authors:   University of Customs and Finance, Ukraine, Lohvyn Andrii
Published: February 2021

Legal disputes are inseparable part of the life of society. The task of the state is to create conditions for resolving disputes and to defend the rights and interests of citizens that are protected by law. Legal relationships are undoubtedly the sphere of potential disputes. The search for alternative and effective procedures of resolving such disputes is an important issue. At the same time, the main legal issue of the tax sphere is mainly to define and effectively ensure the limits of freedom and necessity in the behavior of taxpayers through the relevant legal, legislative norms, protection of property rights of individual taxpayers and the interests of society. Alternative Dispute Resolution або ADR include mediation, which gained broad recognition all over the world, including the European Union, which is postulated at the legislative level. It is often used, which makes it possible to prevent the negative consequences for the dispute parties as early as at the initial stage and avoid the expensive and lengthy trial. It gained recognition in resolving a wide range of disputes and arguments, beginning with the disputes in local communities and finishing with complex multi-lateral disputes in the commercial and public spheres. In many countries it is legislatively stipulated. Today, the institution of the alternative dispute resolution in the modified form is partially present in the Ukrainian legislation and in practice, at the same time, it is difficult to call the sphere of the alternative methods of dispute resolution well-developed. In this case, the lawyers and scientists discuss a wide implementation of the alternative ways, including mediation, virtually in all branches of law. The article, taking into account the practice of using alternative dispute resolution in other countries (international experience), identifies the possibility of using them in Ukraine as a separate permanent institution of pre-trial dispute resolution in the field of tax relations (the result of application of which can be achievement of reconciliation and/or tax compromise), which is directed at the improvement of tax administration. The concept of the tax compromise was also formulated and scientifically substantiated conclusions in the stated area were made.
VOLLEYBALL AS A MEANS OF PHYSICAL EDUCATION OF STUDENTS OF HIGHER EDUCATION INSTITUTIONS
Authors:   National University «Odessa Law Academy», Ukraine, Antipova Zhanna , Barsukova Tatyana ,   National University «Odessa Law Academy», Ukraine
Published: February 2021

The proposed monograph contains recommendations for the organization of training volleyball classes with students of higher education institutions in order to improve the development of special qualities and skills of volleyball players. The system of volleyball classes is presented, the technique of development of special and general physical training and exercises promote development of physical qualities, formation of specialized motor skills and abilities, strengthening and maintenance of health of students taking into account specificity of our, legal educational institution. Experimental work on the application of the program of the initial stage of learning the game, which was conducted at the National University “Odessa Law Academy” in the 1st year of the Judicial and Administrative Faculty. Improvement of methods and techniques, innovative approach in conducting volleyball lessons is an urgent problem, as modern education in a law school places high demands on students, including their health, because the professional status of a lawyer involves high level of physical and mental health. Developed and submitted exercises can positively affect the level of skill involved, prepare them for participation in competitions. The recommendations given in the proposed monograph can be used by teachers of higher education institutions to conduct classes with students; students who learn to play volleyball on the basis of the “minimum” course, as well as for those who want to learn the game, training at the place of residence or on vacation.
MODELLING AND OPTIMIZATION OF WAVEGUIDE POLARIZERS WITH THE ACCOUNT OF IRISES THICKNESS
Authors:   Igor Sikorsky Kyiv Polytechnic Institute, Ukraine, Bulashenko Andrew , Piltyay Stepan ,   Igor Sikorsky Kyiv Polytechnic Institute, Ukraine
Published: February 2021

Today, there is a continuous improvement of modern satellite telecommunication systems caused by the requirements of constantly increasing information volumes. The fundamental elements of such systems are antennas with polarization processing of signals. This processing is mainly performed using microwave waveguide polarizers and orthomode transducers. Therefore, the development and optimization of new waveguide polarizers is a relevant engineering problem. The simplest from the technological point of view are the polarizers based on waveguides with irises. Analysis and optimization of electromagnetic characteristics of a polarizer based on a square waveguide with irises are the goals of the presented research. To solve this optimization problem we have created a new mathematical model, which allows to investigate the influence of the design parameters of the polarizer on its electromagnetic characteristics. A new mathematical model of the polarizer based on square waveguide with irises was created using wave transmission and scattering matrices of the structure elements. Developed mathematical model takes into account the thickness of the irises. A new mathematical model of a waveguide polarizer is based on the general wave scattering matrix. This matrix was calculated using the theory of microwave circuits. The main characteristics of the square waveguide polarizer were expressed through the elements of this matrix. The developed new mathematical model of a square waveguide polarizer with irises takes into account the heights of the irises, the distances between them and their thickness. The new mathematical model is simpler and faster for the determination of the electromagnetic characteristics of the waveguide polarizer compared to the finite integration technique, which is often applied to analyze microwave devices for various purposes. In addition, developed new mathematical model of the waveguide iris polarizer allows to estimate the variations of all required electromagnetic characteristics if the structure parameters deviate from their optimal values. Using the created mathematical model we have carried out the optimization of the polarizer matching and polarization characteristics in the operating satellite Ku-band 10.7–12.8 GHz. Simulated optimum design of the waveguide polarizer provides VSWR for horizontal and vertical polarizations less than 3.26. Optimized differential phase shift is 90° ± 4.2°. Axial ratio of the waveguide iris polarizer is less than 1.43 dB. Corresponding XPD is higher than 21.7 dB.
THE WAVE PROCESSES IN THREE-LAYER SHELLS OF ROTATIONWITH TAKING INTO ACCOUNT THE DISCRETE FILLER AT NON-STATIONARY LOADS
Authors:   S.P. Timoshenko Institute of Mechanics of the National Academy of Sciences of Ukraine, Ukraine, Meish Vladimyr , Meish Yuliia ,   National Transport University, Ukraine
Published: February 2021

Thin-walled shell structures in the form of plates and shells of various shapes have a high bearing capacity, lightness, and relative ease of manufacture. Three-layer shell elements, which consist of two bearing layers and a filler, which ensures their joint work, are widely used in mechanical engineering, industrial and civil construction, aviation and space technology, shipbuilding. When calculating the strength of three-layer shell structures with a discrete filler under dynamic loads, it becomes necessary to determine the stress-strain state both in the area of a sharp change in the geometry of the structure and at a considerable distance from the heterogeneity. The complexity of the processes that arise in this case necessitates the use of modern numerical methods for solving dynamic problems of the behavior of three-layer shell elements with a discrete filler. In this regard, the determination of the stress-strain state of three-layer shells with a discrete filler under non-stationary loads and the development of an effective numerical method for solving problems of this class is an urgent problem in the mechanics of a deformable solid. On the basis of the theory of threelayered shells with applying the hypotheses for each layer the nonstationary vibrations threelayered shells of revolution with allowance of discrete fillers are investigated. Hamilton-Ostrogradskyy variational principle for dynamical processes is used for deduction of the motion equations. An efficient numerical method for solution of problems on nonstationary behaviour of threelayers shells of revolution with allowance of discrete fillers are used. The wide diapason of geometrical, and physico-mechanical parameters of nonhomohenes threelayered structure are considerated. On the basis of the offered model nonstationary problems of the forced nonlinear vibrations of threelayered shells of revolution of various structure are solved and analysed. The basis of the developed numerical method for the study of nonstationary oscillations is the application of explicit finite-difference schemes to solve the initial differential equations in partial derivatives. The theory is based on the relations of the theory of three-layer shells of revolution taking into account the discreteness of the filler, which are based on the hypotheses of the geometrically nonlinear theory of shells and rods of the Timoshenko type.