bluuebunny/crossref_metadata_2025 huggingface dataset:
SYMMETRICAL SYNTHESIS AND CHARACTERIZATION OF FIVE-COORDINATE In(III) PORPHYRINS WITH SALICYLIC ACID DERIVATIVES
Authors: D. Sharma  , D. Gupta  , S. Kundan  , G. D.Bajju  , S.Ravichandran
Published: March 2023

Investigations of the In(III)porphyrin complexes with substituted salicylates(X) as axial ligands have been carried out using electronic and biological studies. Electronic spectra of the complexes are accompanied by shifting of wavelength towards hypsochromic/blue-shift or bathochromic/red-shift along with 'ƒ' values decided by the nature of the functional groups attached to the salicylate ligand. IR frequencies appear at 550cm-1–400cm−1 for In–N(Por) and at 650cm−1–700cm−1 for In–OSA. 1HNMR spectra reveal the merging of the salicylate ring with that of the protons of the macrocyclic ring. The 13CNMR studies confirm the resonance of the meso-carbon tetraphenyl porphyrin ring between 130ppm to 160ppm and the salicylate ring carbons in the region of 110ppm to 165ppm. Thermal analysis confirms the presence of indium nitride (In-N) in an argon atmosphere from 0oC to 900oC. Cyclic voltammetry(CV) revealed the reduced or oxidized properties of these complexes lead to the generation of π-anion or cation radicals by two one-electron transfer reactions. In(III)porphyrin complexes with substituted salicylates were also screened for in-vitro antifungal activity(%inhibition) against the microbe "Acremonium fusidoides spp." using the PDA method, which shows that the percentage inhibition is inverse to the diameter of the colony. The freeradical scavenging or antiradical activity (%RSA) by the DPPH method reveals that these complexes were absorbance and concentration-dependent.
PHOTOCATALYTIC DEGRADATION OF RHODAMINE B UNDER UV USING DOUBLE-LAYER ZnO: Fe THIN FILM
Authors: Sutanto Heri , Alkian Ilham , Hasanah Ulfatun , Hidayanto Eko , Marhaendrajaya Indras , Priyono
Published: March 2023

Waste dyes are a major source of water pollution, which is a critical environmental issue. The purpose of this study is to synthesize double-layer ZnO: Fe 5-20% thin films and investigate the degradation of rhodamine B in these films. The creation of the ZnO phase with the wurtzite hexagonal structure may be seen in the thin film X-ray diffraction pattern. Only marginally lessened energy bandgap (3.11-3.09 eV), optical transmission spectra, and lattice strain was seen after Fe was added to ZnO thin films. With increasing Fe concentration, it was found that the hydrophilicity and photocatalytic characteristics of ZnO thin films considerably decreased, as shown by the contact angle going from 51.4 to 70.71 and the decomposition efficiency going from 61.46% to 50.35%. The double-layer ZnO layer's optical characteristics diminish as the Fe concentration rises.
PHYTOCHEMICALS ANALYSIS AND CYTOTOXIC ACTIVITY OF Lansium domesticum Corr EXTRACT-CISPLATIN COMBINATION AGAINST PANC-1 CELL LINE
Authors: Lubis M.F. , Hasibuan P.A.Z. , Kaban V.E. , R. Astyka
Published: March 2023

The use of chemotherapy such as cisplatin in treating cancer alone can cause many problems, including side effects and resistance. Therefore, currently, efforts are being made to combine cisplatin with natural ingredients such as ethanol extract from duku leaves. Then extracted using ethanol as a solvent. The secondary metabolites of the extract were identified using LC-MS/MS with mobile phase A (0.1 percent formic acid in water) and phase B (0.1 percent formic acid in acetonitrile). The extract and cisplatin were determined by their IC50 values as the basis for carrying out the combination test using the MTT method. All data obtained were processed with Microsoft Excel and analyzed with SPSS 23. The ethanol extract of duku leaves contains about 15 compounds that cannot be clearly identified because they are not listed in the LC-MS/MS library used. Interestingly, there were 5 compounds that gave a sufficiently large absorption each at a retention time of 1.08; 5.18; 9.45; 9.57; 10.70; and 10.82. Cisplatin has stronger cytotoxic properties than the extract with IC50 values of 3.02±0.05 µg/mL and 28.61±0.13 µg/mL, respectively. The combination of these two substances is synergistic with a combination index <1. the combination of extract and cisplatin at doses of 1.75:0.75 and 1.75:0.375 had very strong synergy with a combination index of 0.01 (p>0.05). However, the mechanism of action of this combination is not yet known clearly, so further research is needed on it.
SYNTHESIS OF SILVER NANOPARTICLES USING ETHANOLIC EXTRACT OF Nelumbo nucifera Gaertn. LEAF AND ITS CYTOTOXIC ACTIVITY AGAINST T47D AND 4T1 CELL LINES
Authors: K. Fitri  , M. Andry  , Khairani T. N. , Winata H. S. , A. Violenta  , N. Lubis  , Lubis M. F.
Published: March 2023

The cytotoxic activitiy of silver nanoparticles bio-functionalized by Nelumbo nucifera leaf extracts were examined in the current work. The nanoparticle (AgNPs) was characterized by scanning electron microscopy, UV–visible spectroscopy, and a particle size analyzer. Cytotoxic activity of silver nanoparticles against T47D and 4T1 cells using the MTT method using concentrations of 100 µg/mL, 50 µg/mL, and 25 µg/mL. For comparison, doxorubicin was used at the same dose. The size of the spherical nanoparticle was 66.4±0.93 nm and the polydispersity index was 0.23±0.05. Silver nanoparticles have anti-cancer properties against T47D and 4T1 cell lines based on inhibitory concentration. The inhibitory concentration (IC50) of AgNPs on T47D and 4T1 cells were obtained at 12.10±0.08 𝜇g/mL and 98.77±1.27 𝜇g/mL, respectively. Meanwhile, the IC50 values of doxorubicin in T47D and 4T1 cells were 4.45±0.03 𝜇g/mL and 36.77±1.15 𝜇g/mL, respectively. Overall, the results revealed that the green-synthetized silver nanoparticle had cytotoxic effects on breast cancer cells in comparison to doxorubicin.
THE RECYCLING OF GRAPHITE FROM SPENT LITHIUMION BATTERIES AS NEW LITHIUM-ION BATTERIES ANODE MATERIALS
Authors: mah Y. L. Ni’ , S. Suprapto  , Puteri C. A. , A. Subhan
Published: March 2023

Spent lithium-ion batteries (LIBs) anode material has been successfully reused as a new LIBs anode material by mechanical separation, chemical purification, and calcination. The materials obtained were characterized using XRD and FTIR. LIBs anode slurry was made with a composition of active material: binder: additive = 85: 10: 5 that was mixed in N-methyl-2- pyrrolidone (NMP) solvents. Graphite of 5% was added to the anode active material to increase the graphite content in the anode materials. The battery performance was determined using cyclic voltammetry and the charge-discharge test. The charge-discharge test shows that the spent LIBs anode treated without the addition of graphite has the highest efficiency (98%) and capacity (charge 148.374 mAh/g and discharge 151.489 mAh/g). The capacity values were higher than the anode materials without treatment.
TREATMENT OF WASTEWATER GENERATED FROM AUTOMOBILE SERVICE STATIONS USING CORN COB AS ADSORBENT
Authors: Sudhir Shruti , K. Prasanna
Published: March 2023

Automobile wastewater is one among the heavily contaminated wastewater consisting of harmful elements such as surfactants, oil and grease, dust particles, and various dissolved and suspended solids. In this study, car wash water from an automobile wash center in Chennai, Tamil Nadu was collected and treated with waste from corn crops that is inedible. The increase in automobile industries and similar wash centers is contributing to environmental contamination. Due to the low cost and availability, the efficiency of removal of pollutants, and since it promotes environmental sustainability, natural materials are adopted more than chemicals. The study adopted using a column adsorption process and it showed good results in the physiochemical characteristics where it has adsorbed oil and grease, TDS, and TSS. Oil and grease removal by 71.4% was observed whereas the biochar was found to be effective with an 89% reduction in total dissolved solids and more than 50% decrease in parameters such as TSS, COD, conductivity, oil and grease, and total alkalinity. The adsorption isotherm was studied with varying particle size and bed height along with the comparison of removal efficiency of various parameters in this experimental investigation.
ULTRASONICALLY ASSISTED SYNTHESIS OF CHROMEN-2- ONE-1,2,3-TRIAZOLES AND In-vitro ANTICANCER ACTIVITY
Authors: Kumar Ega Jagadeesh , Peddapyata Prashanth Raja , Siddoju Kavitha
Published: March 2023

Synthesis of new series of chromen-2-one-1,2,3-Triazoles (6a-6j) was reported using the help of key methods such as [3+2]-cycloaddition and ultrasound. All compounds were further evaluated for their in vitro anticancer activity profile in three human cancer cell lines MCF-7(breast), A-549 (lungs), and HeLa (cervical). Among all, three compounds namely 6c, 6f, and 6j showed the most promising activity against three lines, when compared with the etoposide.
EFFICIENT SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(3-ARYL-4,5-DIHYDRO-1H-PYRAZOL-5-YL)-2- (TRIFLUOROMETHYL)-1,8-NAPHTHYRIDINES
Authors: Nageswara Rao Ambala , Hariprasad Dara , Venkanna Chinthala
Published: March 2023

An efficient synthesis of 3-(3-Aryl-4,5-dihydro-1H-pyrazol-5-yl)-2-(trifluoromethyl)-1,8-naphthyridines 5(a-h) was achieved by the cyclo condensation of 1-Aryl-3-(2-(trifluoromethyl)-1,8-naphthyridin-3-yl)prop-2-en-1-ones(4a-h) with hydrazine hydrate. The compounds 4(a-h) were synthesized through a three-step procedure starting from ethyl 2-(trifluoromethyl)-1,8-naphthyridine-3-carboxylate (1). Antibacterial and antifungal activities of the final compounds 5(a-h) have been screened and compound 5h exhibited significant inhibition of bacterial and fungal growth. The structures of compounds 3-5 are assigned on the basis of their elemental analysis and spectral (IR, 1H NMR, and MS) data.
DETERMINATION OF PSEUDOEPHEDRINE HYDROCHLORIDE AND TRIPROLIDINE HYDROCHLORIDE SIMULTANEOUSLY BY USING AREA UNDER CURVE SPECTROPHOTOMETRY ULTRAVIOLET
Authors: Tarigan R. E. , Sianturi D. M. , S. Nadya
Published: March 2023

Anti-influenza drugs on the market contain a combination of more than one active substance in one preparation. An example is pseudoephedrine hydrochloride and triprolidine hydrochloride in tablet form. The goal of this research is to determine pseudoephedrine hydrochloride and triprolidine hydrochloride simultaneously by using the area under curve spectrophotometry. The area under the curve in the wavelength range of 306.6-316.6 nm and 253.6-263.6 nm were selected to determine pseudoephedrine hydrochloride and triprolidine hydrochloride, respectively. The method was linear at a concentration range of 180-500 μg/mL (correlation coefficient 0,9994) and 6-18 μg/mL (correlation coefficient 0,9996) for the pseudoephedrine hydrochloride and triprolidine hydrochloride, respectively. The mean % recoveries for pseudoephedrine hydrochloride and triprolidine hydrochloride were 100.01% and 100.07%, respectively. This method was successfully used to determine pseudoephedrine hydrochloride and triprolidine hydrochloride simultaneously.
NOVEL SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF N-(5BROMO-2-(5-PHENYL1,3,4-OXADIAZOL-2-YL)NAPHTHA[2,1-B]FURAN-1- YL)ACETAMIDE AND N-(5-NITRO-2-(5-PHENYL-1,3,4- OXADIAZOL-2-YL)NAPHTHA[2,1-BFURAN-1-YL]ACETAMIDE AND THEIR DERIVATIVES
Authors: Nagarsha K. M. , Sharanakumar T. M. , D. Ramesh  , Kumar N. Y. Praveen , Kumarswamy M. N. , Ramesh D. R. , Latha K. P.
Published: March 2023

The novel derivatives of naphtho-furan such N-(5bromo-2-(5-phenyl-1,3,4-oxadiazol-2-yl)naphtha[2,1-b]furan-1- yl)acetamide (8), N-(5-bromo-2-(hydrazinecarbonyl)naphtha[2,1-b]furan-1-yl]acetamide (7), ethyl-1-acetamido-5- bromonaphtho[2,1-b]furan-2-carboxylate (6), N-(5-nitro-2-(5-phenyl-1,3,4-oxadiazol-2-yl)naphtha[2,1-bfuran-1- yl]acetamide (5),N-(2-(hydrazinecarbonyl)-5-nitronaphtho[2,1-b]furan-1-yl)acetamide (4), ethyl-1-acetamido-5- nitrpnaphtho[2,1-b]furan-2-carboxylate (3), are prepared by ethyl-1-acetamidonaphtho[2,1-b]furan-2-carboxyate and ethyl 1-aminonaphtho[2,1-b]furan-2-carboxylate. All newly synthesized compounds were confirmed by Mass, NMR, and FTIR spectroscopic techniques. Those compounds were used for antimicrobial activity it exhibits good antibacterial and anti-functional activity.
KINETIC ANALYSIS OF OXIDATION OF α-HYDROXY ACIDS BY TETRAMETHYLAMMONIUM CHLOROCHROMATE IN MICELLES MEDIUM
Authors: P. Rajkumar  , N. Buvaneswari  , P. Selvi  , N. Geetha  , A. Subash
Published: March 2023

The oxidation of pentaamineCo(II)complexes of bounded and unbounded α-hydroxy acids by Tetramethylammonium Chlorochromate (TMACC) is studied at four different temperatures in micelles medium and the rate of the reaction is observed through UV-Visible spectrophotometer at 504 nm. Under constant solution conditions, the addition of micelles enhances the rate of the reaction. The kinetic and stoichiometric data are consistent with the appropriate mechanism.
PHYTOCHEMICAL ANALYSIS IN ROOTS AND TUBERS OF BOTSWANA MEDICINAL PLANTS- Solanum Aculeastrum dunal, Elephantorrhiza elephentina, Cadaba aphylla (Thunb) AND Adenia glauca
Authors: Immaculate A. Anitha , Vimala J. Rosaline , Takuwa David T.
Published: March 2023

Medicinal plants play an important role in our life. Worldwide modern drugs used in healthcare are derived from plants. Several Rhizomes and tubers are important for people due to their edible as well as medicinal properties. The Rhizome and tuberous plants namely Solanum aculeastrum dunal, Elephantorrhiza elephentina, Cadaba aphylla (Thunb), and Adenia glauca which are indigenous plants of Botswana have been so far employed in the treatment of cutaneous, subcutaneous parasitic infection, wounds, dermatological diseases, gastrointestinal system disorders, sexual dysfunction, and sexually transmitted infections. This study was conducted to identify the phytoconstituents by subjecting them to Ultrasound-Assisted Extraction (UAE) with distilled water, methanol, ethanol, chloroform, and hexane, each extract of which was further applied to the phytochemical screening through qualitative and quantitative tests. The extracting yields of Solanum aculeastrum dunal with different solvents gave the values of 13.0% (hexane), 13.0% (chloroform), 66.6% (ethanol), 66.6% (methanol) and 46.6% (aqueous), Elephantorrhiza elephentina 13.0% (hexane), 20.0% (chloroform), 66.6% (ethanol), 80.0% (methanol) and 86.0% (aqueous), Cadaba aphylla 60% (ethanol), 66.6% (methanol) and 53.3% (aqueous), Adenia glauca 40% (ethanol), 40.0% (methanol) and 46.6% (aqueous). Standards were used to determine the total content of alkaloid, flavonoid, phenol, saponin, and tannin (Atropine, Quercetin, Gallic acid, Tannic acid, and Quillaja). The regression coefficient (R2 ) was calculated and for Alkaloids, it is 0.9925, flavonoid (0.9953), phenol (0.9978), tannin (0.9955), and saponin (0.9912) respectively. These medicinal plants have produced many phytochemical substances in quantitative analysis, which will be applied in future drug analysis research
DETERMINATION OF TOTAL PHYTOCHEMICAL COMPOUNDS FROM ETHANOL EXTRACT NANGKA (Artocarpus heterophyllus Lam.) LEAVES AND ANTIOXIDANT ACTIVITY FROM NORTH SUMATERA, INDONESIA
Authors: P. Sinaga Suharni , Situmorang R.F.R. , N. Singarimbun  , W. Lestari  , K. Gurning
Published: March 2023

Nangka (Artocarpus heterophyllus Lam.) has various nutritional contents and abundant bioactive compounds. Potential bioactive compounds including phenolic and flavonoid categorized as antioxidants. This study aimed to determine the levels of phenolics and flavonoids and to test their potential activity as antioxidants from the ethanol extract of nangka leaves. The extraction process used ethanol by maceration method, colorimetric determination of phenolic, flavonoid, and tannins content, and determination of antioxidant activity by 2,2-dipicryl -1-hydrazil (DPPH) method using UV-Vis spectrophotometry. Determination of phenolic content was measured at a maximum wavelength of 765 nm with gallic acid as the standard, flavonoid content was measured at a maximum wavelength of 431 nm with quercetin as standard, tannins content was measured at a maximum wavelength of 745 nm with tannic acid as standard and the determination of antioxidant activity at a maximum wavelength of 517 nm with positive control of vitamin C. The results showed that the ethanolic extract of nangka leaves has phenolic content with a total phenolic content of 27.654±0.054 mg GAE/g d.w ethanolic, flavonoid content of 2.978 ±0.192 mg QE/g d.w ethanolic, tannins content 0.46 ± 0.017 mg TAE/g d.w ethanolic extract and antioxidant activity (IC50) 25.561±0.055 ppm which categorized as a very strong antioxidant
THE MESOPOROUS BIOSILICA CATALYST FROM ANDONG BAMBOO LEAF FOR DIRECT-PYROLYSIS REACTION
Authors: L. Efiyanti  , Saputra N.A. , Indrawan D.A. , I. Winarni  , B. Pranoto  , N. Hastuti  , Z. Fadhlulloh  , Y. Rahayuningsih  , S. Wibowo  , S. Darmawan  , Yuniawati  , Gusmailina  , S. Komarayati  , D. Hendra  , G. Pari
Published: March 2023

Silica is a functional material with broad benefits, including as a catalyst. It is essential to substitute synthetic silica with natural silica to support green technology and economic development. The silica extraction process from bamboo leaf waste was carried out using an acid-base solution and a cetyltrimethylammonium bromide (CTAB) template structure to get mesoporous biosilica. This mesoporous biosilica was then applied as a biocatalyst for α-cellulose direct pyrolysis. Biosilica was characterized using various analyses including Fourier Transform Infrared Spectroscopy (FTIR), Surface Area Analyzer (SAA), Scanning Electron Microscope (SEM), gravimetric methods, and applications to the cracking process using Pyrolysis Gas Chromatography Mass Spectrometry (Py-GCMS). The CTAB addition is divided into three variations, namely 0.05:1, 0.1:1, and 0.2:1. The data found that the highest yield was produced in the CTAB biosilica 0.2:1, and the silica content in the bamboo ash and CTAB biosilica sample was 60% and 90.5- 93.6%, respectively. The surface acidity of the biosilica ranged from 1.97 and 2.1 mmol/g. The essential groups in the biosilica formed are hydroxyl, silanol, and siloxane groups, with the morphology of the silica being observed to be irregular in shape, forming aggregates like coral. The surface area of biosilica with the ratio of 0.05:1, 0.1:1, and 0.2:1 was 177.068 m2 /g, 661.166 m2 /g, and 684.852 m2 /g, respectively, with a pore size distribution following the mesoporous class. The α-cellulose cracking using py-GCMS with a biosilica catalyst at CTAB variations of 0.05:1, 0.1:1, and 0.2:1 yielded a hydrocarbon content of 44.88%; 61.6%; and 30.4%.
SQUID PENS MEDIATED SILVER NANOPARTICLES SYNTHESIS, ITS CHARACTERISATION, AND BIOLOGICAL ACTIVITIES
Authors: Ragunathan Venkataraghavan , Sudharsan Meenambiga Setti , S.R. Roshini , Sundar Gomathy , Chithra K.
Published: March 2023

This research scintillates the synthesis of silver nanoparticles from chitosan (C-AgNps) from squid pens as a reducing and stabilizing agent and assesses its antioxidant, antibacterial, and anticancer potentials. The nanoparticles were 240 to 290 nm with excellent stability of +98.2 mV. The C-AgNps possessed an excellent 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity with an IC50 of 6.65 µg/mL. The C-AgNps showed exceptional antibacterial properties against S. aureus, B. subtilis, P. aeruginosa, and E. coli using a good diffusion assay. The C-AgNps also showed outstanding anticancer properties against A375 human skin malignant melanoma. Thus, the C-AgNps could be used as antimicrobial and anticancer agents for novel therapeutics after lead optimization and in-vivo clinical trials.
CETYL TRIMETHYL AMMONIUM BROMIDE ASSISTED OXIDATION OF HYPOXANTHINE AND XANTHINE USING Mn(VII) IN AQUEOUS BRONSTED ACID MEDIA: A KINETIC AND MECHANISTIC STUDY
Authors: Reddy A. Ramakrishna , Reddy A. Panasa , Chary M. Thirumala , Rajanna K.C.
Published: March 2023

Cetyl trimethyl ammonium bromide (CTAB) assisted Oxidation of hypoxanthine (HXAN), and xanthine (XAN) alkaloids by Mn(VII) occurred smoothly in presence of aqueous Bronsted acid (HClO4, H2SO4) media. The rate of oxidation of HXAN, XAN by Mn(VII) was enhanced due to an increase in [HClO4] / [H2SO4] in the presence of CTAB at a constant temperature. Reaction kinetics obeyed I-order in [Mn(VII)], [HXAN], or [XAN] at constant temperature and acid concentration in micellar (CTAB) conditions. In this present work, the acidity functions developed by Zucker-Hammett, Bunnett, and Bunnett-Olsen were used for analyzing rate enhancement, and the probable reaction mechanism that involves water moiety in the slow step has been proposed according to the criteria of Bunnett-Olsen.
STUDY OF MOLECULAR INTERACTIONS OF SUBSTITUTED 2-OXO-2-H-CHROMENE-3-CARBOHYDRAZIDE DERIVATIVES IN BINARY SOLVENTS USING ULTRASONIC INTERFEROMETER
Authors: Choudhari P. P. , Raut P. V.
Published: March 2023

At 32°C, the apparent molal volume (v), apparent molal compressibility (k), relative association (RA), and solvation number (Sn) of substituted 2-oxo-2-H-chromene-3-carbohydrazide derivatives in 60% DMF-water were measured. The data is used to determine the interaction that is taking place in the solution. The ultrasonic technique is used to determine the interaction of a solute and a solvent. The variation of factors in binary mixtures with different concentrations indicates a significant interaction between solute and solvent molecules, associative molecular interaction, and ion-solvent interaction.
Response of selected nutrient elements in pea (Pisum sativum L.) leaf tissues to the seed priming-and-drying technology in cucurbitacin phytonematicides
Authors: POFU K. M. , MASHELA P. W.
Published: March 2023

Priming-and-drying technology for pea (Pisum sativum L.) seeds with hypogeal germination showed that the technology could improve plant growth and development, while suppressing nematode population densities, but without information on the potential causal factors for the former. A study was, therefore, conducted in Limpopo Province, South Africa, to investigate the extent to which plant responses could be associated with accumulation of foliar nutrient elements in pea plants post-subjecting pea seeds to the technology. After a 2-h priming of pea seeds in geometric concentration of Nemarioc-AL and Nemafric-BL phytonematicides and then air-dried in ovens at 26ºC for 72 h. Seeds were sown in 20-cm-diameter plastic pots filled with appropriate growing mixture, with one trial in the greenhouse and the other on microplots. At 60 days after sowing, 10 healthy mature leaves per plant were prepared for extraction of nutrient elements through the digestion method and then quantified in Atomic Absorption Spectrophotometer ICPE-9000. Iron, Na, K and Zn in leaf tissues of pea plants versus increasing phytonematicides concentration, regardless of the growing condition, exhibited significant (P ≤ 0.05) negative or positive quadratic equations. In conclusion, results suggested that the priming-and-drying technology could affect pea plant growth through disproportionate accumulation of nutrient elements in foliar leaf tissues.
Influence of crop seasons to quality attributes of watermelon (Citrullus vulgaris L.) and cantaloupe (Cucumis melo L.) in the sub-tropical zone of Vietnam
Authors: MINH NGUYEN PHUOC
Published: March 2023

Watermelon and cantaloupe are vital fruits that supply the basic energy requirement along with reduction in poverty of millions of farmers. However, the nutritional quality is influenced by soil, climatic condition and cultivation technique, adopted by the local farmers which needs to be explored in depth. Therefore, this research was conducted at Chon Thanh district, Binh Phuoc province, Vietnam in 2021 to survey the impact of crop seasons (winter-spring and autumn-winter) on the proximate composition, phenolic content and antioxidant activity of watermelon and cantaloupe fruits. This investigation was carried out on 24 orchards (for watermelon) and 18 green-houses (for cantaloupe) of Binh Phuoc province, Vietnam with total 216 watermelon fruits and 162 cantaloupe fruits in the winter–spring crop from October 2019 to March 2020; and total 216 watermelon fruits and 162 cantaloupe fruits in the autumn-winter crop from April 2020 to September 2020. Results showed that winter-spring provided a minor higher proximate composition, phenolic content and antioxidant activity on both the watermelon and cantaloupe fruits than ones grown in the autumn-winter season. It could be explained by the effect of crop seasons on the growth of fruits and accumulation of quality attributes.
Efficacy of cattle manure in improving the productivity of peanut (Arachis hypogaea) in sandy soil of Central Vietnam
Authors: HOANG T. T. H. , DO D. T. , TRAN T. D. , DUONG C. B. , DO H. T. P.
Published: March 2023

Peanut is an important annual crop in sandy soil of Central Vietnam. Organic fertilizer application plays a key role in improving peanut yield and soil quality. However, research on cattle manure is still limited in sandy soil for peanut crop. Trial consisted of 10 fertilizer treatments with two factors including two application methods and five ratios of inorganic fertilizer and manure and rice straw combinations. They were arranged in a split plot design with three replicates during the spring and summer season of 2021 on the sandy soil at Cat Trinh commune, Phu Cat district, Binh Dinh province, Vietnam. The aims of the study were to evaluate the efficiency of different combinations of organic amendments on the yield of peanut and to examine possible short-term changes in soil characteristics as a result of organic amendments application. The study results showed that application methods and different organic treatments gave higher yields compared with application of inorganic fertilizer alone. The highest peanut yield was found in the application of organic fertilizer from cattle manure+rice straw (1:0.5) and row application with (2.80-3.85 t/ha), increasing (21-27%) compared with application of inorganic fertilizer alone in surface application method and seasons. Cattle manure application improved some soil chemistry properties after the experiment such as OC, CEC, total N, P2O5 and K2O. In conclusion, incorporation of different types of organic amendments improved peanut yield and soil properties more than application of inorganic fertilizer alone.
Теоретичні основи і механізми розвитку науково-педагогічного потенціалу університетів України у контексті розширення інституційної автономії та в умовах воєнного стану
Authors: Скиба Юрій , Жабенко Олександр , Отич Олена , Чорнойван Ганна , Ярошенко Ольга
Published: March 2023

Монографію присвячено проблемі розвитку науково-педагогічного потенціалу університетів України у контексті розширення інституційної автономії та в умовах воєнного стану. На основі аналізу теоретичних основ, вітчизняної та зарубіжної практики розкрито механізми розвитку науково-педагогічного потенціалу університетів України, а також обґрунтовано основні напрями їх модернізації. Запровадження положень монографії спонукатиме розробників освітньої політики, керівників закладів вищої освіти, науковців, науково-педагогічних працівників і здобувачів вищої освіти до подальших досліджень проблеми розвитку науково-педагогічного потенціалу університетів України з метою розроблення / удосконалення стратегій розвитку університетів, підвищення їх рейтингу та конкурентоспроможності в Європейському просторі вищої освіти. Для розробників освітньої політики, науковців, керівників закладів вищої освіти, науково-педагогічних працівників і здобувачів вищої освіти.
Аналіз провідного вітчизняного та зарубіжного досвіду щодо забезпечення ефективності освітньої діяльності в університетах в контексті євроінтеграції та в умовах воєнного стану і післявоєнного відновлення України
Authors: Бородієнко Олександра , Вітренко Юрій , Ворона Вікторія , Дебич Марія , Паламарчук Ольга , Слюсаренко Олена , Таланова Жаннета
Published: March 2023

Препринт «Аналіз провідного вітчизняного та зарубіжного досвіду щодо забезпечення ефективності освітньої діяльності в університетах в контексті євроінтеграції та в умовах воєнного стану і післявоєнного відновлення України» підготовлено за результатами виконання другого етапу наукового дослідження за темою «Політика та механізми забезпечення ефективності освітньої діяльності в університетах України в контексті євроінтеграції та в умовах воєнного стану і післявоєнного відновлення країни» колективом вчених відділу забезпечення якості вищої освіти Інституту вищої освіти НАПН України. На цьому етапі виконання наукового дослідження перед колективом дослідників ставилося завдання здійснити аналіз провідного вітчизняного та зарубіжного досвіду щодо політики та механізмів забезпечення ефективності освітньої діяльності в університетах у контексті євроінтеграції та в умовах воєнного стану і післявоєнного відновлення України. У роботі представлено узагальнення міжнародних документів і кращих практик щодо реалізації та оцінювання освітньої діяльності в закладах вищої освіти України та провідних країн Європи і світу, виявлено стратегічні та практичні підходи до розроблення та реалізації політики та механізмів забезпечення ефективності освітньої діяльності в університетах в контексті євроінтеграції та в умовах воєнного стану і післявоєнного відновлення України. Видання буде корисним для викладачів, дослідників, керівників і здобувачів вищої освіти, а також інших зацікавлених осіб.
Alguns apontamentos sobre o processo de formação pedagógica na área da filosofia e sua decorrente produção de pesquisa e conhecimento
Authors: Siqueira Jean Rodrigues
Published: March 2023

Partindo da distinção indicada por Paulo Freire entre formação e treino em uma área de estudos, este artigo pretende tecer algumas considerações a respeito dos temas do ensino-aprendizado da filosofia e de seu aporte para a produção de conhecimentos nesse campo do saber. Nele será argumentado que, em nosso ambiente acadêmico, essa atividade pedagógica parece privilegiar a dimensão do treino em detrimento daquilo que Immanuel Kant, em um mote famoso, chamava de “aprender a filosofar”. Face esse cenário e seguindo algumas ideias dos professores Ricardo Terra, Marcos Nobre e Oswaldo Porchat, o artigo aponta para a necessidade de revitalização da centralidade do consórcio epistêmico entre os diversos saberes, processo que, contudo, não deve de modo algum descuidar da natureza argumentativa e justificadora da atividade filosófica e de seu discurso.
Oksidasi, Daya Buih, dan Sifat Organoleptik Telur Ayam Ras yang Direndam dalam Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L.)
Authors: Amelia Dina , Suharyanto  , Kaharuddin Desia , Soetrisno Edi
Published: March 2023

Penelitian ini bertujuan untuk mengetahui pengaruh perendaman telur ayam ras dalam ekstrak daun belimbing wuluh (Averrhoa bilimbi L.) (DBW) terhadap tingkat oksidasi, daya buih, dan karakteristik organoleptik telur ayam ras. Telur yang digunakan adalah telur ayam ras yang berumur maksimal 24 jam sejak ditelurkan. Esktraksi dilakukan dengan cara merebus DBW dalam air dengan suhu 85 ºC selama 10 menit, air rebusan kemudian disaring dan digunakan untuk penelitian. Perlakuan yang diaplikasi adalah P0 = tanpa perendaman (kontrol), P1 = perendaman dalam akuades, P2 = perendaman dalam ekstrak DBW 15%, P3 = perendaman dalam DBW 30%, dan P4 = perendaman dalam ekstrak DBW 45%. Tiap perlakuan diulang 3 kali dengan Rancangan Acak Lengkap (RAL). Data dianalisis dengan ANOVA dan uji lanjut DMRT (Duncan’s Multiple Range Test) dengan α = 0,05. Hasil penelitian menunjukkan bahwa perendaman telur dalam larutan ekstrak DBW konsentrasi 15% sudah dapat menekan oksidasi, daya buih yang tidak berubah dan kestabilan buih yang lebih tinggi; skor kecerahan warna yolk, skor bau telur, dan skor tingkat kesukaan yang lebih tinggi tanpa merubah sifat tekstur dan rasa. Kesimpulannya adalah bahwa telur ayam ras memiliki karakteristik fungsional dan organoleptik terbaik pada perendaman dalam ekstrak daun belimbing wuluh dengan konsentrasi 15% serta mampu menekan tingkat oksidasi.
Penambahan EM4 Dalam Konsentrat Terhadap Produktivitas Ternak Kambing
Authors: Padang  , Abdullah Sirajuddin , Cakrawati Sri  Wulan , Nirwana  , Harmoko
Published: March 2023

Ternak kambing Kacang merupakan jenis ternak ruminansia kecil yang banyak dibudidayakan oleh masyarakat, khususnya masyarakat pedesaan hingga pinggiran perkotaan. Tujuan dari dilaksanakannya penelitian ini yaitu untuk mengevaluasi pertumbuhan, status faali, nilai hematologis dan kimia darah kambing Kacang yang diberikan EM4 dengan kadar yang berbeda. Penelitian dilaksanakan pada tanggal 10 Maret hingga 26 Mei tahun 2017 dan bertempat di CV. Prima BREED Kota Palu Sulawesi Tenggah.  Kambing Kacang yang digunakan dalam penelitian sebanyak 15 ekor berjenis kelamin betina dengan kisaran umur ± 10 bulan dan bobot badan 14,40-26,92 kg. Penelitian dirancang menggunakan Rancangan Acak Kelompok dengan 5 perlakuan dan diulang sebanyak 3 kali sebagai kelompok. Sebagai perlakuan yaitu: P1 = Larutan EM4 peternakan 0,0% dari konsentrat; P2 = Larutan EM4 peternakan 0,1% dari konsentrat; P3 = Larutan EM4 peternakan 0,2% dari konsentrat; P4 = Larutan EM4 peternakan 0,3% dari konsentrat; P5 = Larutan EM4 peternakan 0,4% dari konsentrat. Hasil kajian pemanfaatan EM4 dalam konsentrat kambing Kacang menunjukkan adanya pengaruh pada pertambahan bobot badan, efisiensi penggunaan ransum, jumlah sel darah merah, kadar hemoglobin, nilai hematokrit, jumlah glukosa darah dan jumlah urea darah kambing Kacang, akan tetapi tingkat konsumsi bahan kering, suhu tubuh, frekuensi respirasi, frekuensi pulsus, dan jumlah sel darah putih kambing tidak menunjukkan adanya pengaruh nyata.
Profil Kimia Darah Domba Ekor Gemuk Setelah Pemberian Linseed Dengan Berbagai Karakteristik Fisik Dalam Complete Feed
Authors: Widyawati Susi Dwi , Hanifa Aqni , Hadi Rendi Fathoni , Sudiyono  , Handayanta Eka , Nuraini Dian Meididewi
Published: March 2023

Linseed merupakan bahan pakan potensial dengan kandungan protein dan lemak yang tinggi. Untuk mempertahankan kandungan lemak dan protein tersebut, linseed diproduksi dalam berbagai karakteristik. Penelitian ini bertujuan untuk menganalisis kandungan kimia darah pada domba ekor gemuk (DEG) yang diberi linseed dengan berbagai karakteristik dalam complete feed (PK). Penelitian ini menggunakan rancangan acak lengkap pola terarah. Sebanyak 15 ekor DEG dengan berat dan umur seragam dibagi menjadi 5 kelompok perlakuan ransum berbeda. Kelompok perlakuan terdiri dari P1: 100% PK; P2: 90% PK + 10% linseed; P3: 90% PK + 10% tepung linseed tanpa proteksi; P4: 90% PK+10% tepung linseed terproteksi tannin; dan P5: PK 97% + 3% minyak linseed (terproteksi saponifikasi). Perlakuan diberikan selama 105 hari dan darah setiap ekor domba dikoleksi pada hari ke 105 untuk dianalisis kandungan kimianya. Hasil pemeriksaan darah menunjukan bahwa kadar kolesterol (HDL dan LDL) darah tidak berbeda nyata pada setiap kelompok. Kadar trigliserida setiap kelompok berbeda, dengan kadar tertinggi pada kelompok P2. Kadar trigliserida dan glukosa yang rendah ditemukan pada domba dengan ransum yang mengandung linseed yang terproteksi. Dapat disimpulkan bahwa pemberian linseed dengan berbagai karakteristik pada ransum domba tidak memberikan dampak negatif pada komponen kimia darah domba.
Single-centre descriptive study of adverse events reported after anti-COVID vaccination
Authors: Giancane Fabio , Cianciulli Angelo , De Chiara Silvia , Iannelli Alessandra , Finizio Marika , Frammartino Rosetta , Lombardi Andrea
Published: March 2023

Introduction: In Italy, approximately 80.5% of the population has completed the primary anti-COVID vaccination cycle with approximately 141 million doses administered. With the introduction of new measures to counter the spread of COVID-19, including compulsory vaccination for certain categories of people, the population expressed fears about the safety and adverse effects of SARS-CoV-2 vaccines. Several factors, such as gender and age, could have influenced the outcomes associated with the vaccine. Our single-centre work seeks to provide such evidence with respect to Pfizer/BioNTech’s BNT162b2 (Comirnaty) and AstraZeneca’s AZD1222 (Vaxzevria) vaccines. Materials and Methods: Single-centre descriptive study carried out on a sample of subjects who underwent anti-COVID vaccination at the ‘San Giovanni di Dio e Ruggi d’Aragona’ AOU vaccination centre in Salerno. Patients who reported a suspected adverse reaction after receiving a dose of vaccine were included in the study. The regional vaccine platform SORESA and the VigiFarmaco portal were used to collect the data. Results: During the period covered by the study, 126,928 doses of SARS-CoV-2 vaccine were administered. The Pfizer-BioNTech vaccine group comprised 124,138 administrations. The AstraZeneca vaccine group consisted of 2,790 administrations. 287 post-vaccination adverse reaction reports entered in the National Pharmacovigilance Network were considered. In most of the reactions reported, for both vaccines considered, the symptomatology was attributable to local reactions at the injection site. At the systemic level, however, we noted the prevalence of non-specific events such as fever, headache and diffuse arthromyalgia. Conclusions: Based on our results and comparison with the literature, the data collected on the vaccines considered in the study suggest a favourable safety profile for their large-scale use. The rate of minor adverse events turned out to be low, with similarly reassuring data compared to serious adverse events, such as not to justify hesitation towards vaccination for COVID-19 disease control.
Efficacy of Ginger Moxibustion in Management of Local Swelling and Pain at Injection Sites of COVID-19 Vaccines
Authors: Weng Jianyue , Li Wei
Published: March 2023

Ginger moxibustion is characterized by performing easily, activating local blood circulation, warming meridian and unblocking collateral obviously.In order to observe the therapeutic effects of ginger moxibustion for local swelling and pain after COVID-19vaccines, 36 cases were randomly divided into 2 groups, of whom 18 were treated with ginger moxibustion and 18 treated with hot compress. The results showed a cure rate of 100% with a total effective rate of 100% in the ginger moxibustion group, while 27.8% and 44.4% respectively in the hot compress group. The comparisons between the two groups in the cure rate and the total effective rate showed significant differences (P
Clinical Progress Research on Oral Care for Patients with Critical Illness
Authors: Lian Wen
Published: March 2023

In the nursing of patients with critical illness, the oral health of patients will be seriously affected because it is difficult for patients to complete oral care independently. Various microbial pathogens are deposited in patient biofilms as well as in oral secretions and are continuously transmitted. Under the condition of positive pressure ventilation, these pathogenic bacteria will enter the lower respiratory tract of patients, leading to nosocomial pneumonia infection in patients. This will not only significantly prolong the ICU stay time of patients, but also increase the mortality rate of patients. Therefore, it is necessary to strengthen the oral care of patients to reduce the number of bacteria in the patient's pharynx. This is one of the important methods to prevent nosocomial pneumonia infection in patients. For this reason, this article studies the clinical progress of oral care for patients with critical illness, in order to provide some reference for relevant personnel.
Analysis of Preoperative Psychological Characteristics of Patients with Enterostomy
Authors: Fang Jing , Yu Chun , Zou Xiaocui , Yuan Tingting , Zhang Jing
Published: March 2023

Enterostomy is to resect the diseased intestinal tract through surgery, free a section of normal intestinal tract, sew its opening on the abdominal wall, communicate with the intestinal tract, and use it to excrete metabolic waste in the intestinal tract. It is a common surgical method for cancer, which can save and prolong the life of patients. Intestinal stoma patients not only bring inconvenience to life, but also have physical and psychological problems such as depression, anxiety, insomnia, fatigue, and dyspnea, which seriously affect normal social activities. Therefore, attention should be paid to both physical and mental care of stoma patients. Family resilience refers to the support of family members to help patients get out of the plight of illness. Dual support and coping theory refers to the mutual support between patients and their main caregivers to achieve a stable relationship between family members and to jointly cope with the disease process. Quality of life is especially important. This article reviews the psychological characteristics of patients with enterostomy based on family resilience and dual support coping, aiming to provide reliable theoretical knowledge and nursing programs for postoperative physical and mental recovery of patients with enterostomy.
Perioperative Nursing of Puerperae with Pregnancy Associated with Cardiac Disease and Pulmonary Arterial Hypertension
Authors: Meng Peiyan
Published: March 2023

Objective — To explore the perioperative nursing effect of puerperae with pregnancy associated with cardiac disease and pulmonary arterial hypertension. Methods — Sixty puerperae with pregnancy associated with cardiac disease and pulmonary arterial hypertension who were admitted to XX Hospital from June 2020 to July 2021 were selected as the research objects. According to hospitalization number, they were randomly divided into experimental group and control group, with 30 cases in each group. The patients in the control group were treated with routine care, and the patients in the experimental group were treated with clinical pathway nursing. The physical indicators and clinical effects of the two groups of parturients before and after nursing were compared. Results — After monitoring and nursing, the comfort score of the pregnant women in the observation group was significantly higher than that of the pregnant women in the control group, and the difference was statistically significant (P<0.05); the hospitalization expenses and length of stay of the pregnant women in the observation group were significantly less than those of the control group, the difference was statistically significant (P<0.05); after treatment, the maternal satisfaction of the observation group (83.67%) was significantly higher than that of the control group (40.82%), and the difference was statistically significant (P<0.01). Conclusion — On the basis of basic monitoring and nursing care, the implementation of clinical pathway nursing for puerperae with pregnancy associated with cardiac disease and pulmonary arterial hypertension can effectively improve the comfort and satisfaction of the patients, and improve the rehabilitation level and quality of life of the puerpera. The safety of infants is of great significance and has good clinical value in clinical application.
Statistical Thinking and New Forms of Contemporary Art under the Background of Big Data
Authors: Wang Zheng
Published: March 2023

Currently, the rapid emergence of the digital economy has spawned the arrival of the era of big data.With the rapid development of science and technology, Chinese has also entered the era of big data for contemporary art.The engagement of big data in every aspect of our life has begun to influence the development process of Chinese contemporary art, which has also begun to shape a new form of Chinese contemporary art, with many creation modes emerging at home and abroad. The influence of the era of big data is first reflected in many aspects, such as digital art media, art collection and trading market, art management education, etc. In some colleges and universities, design disciplines, such as art and technology, digital media art and interactive design, have emerged to meet the needs of the development of contemporary science and technology and art. They are new forms of art expression at the historic moment with great development prospects and possibilities. This paper mainly studies the influence and change of the development of big data on the contemporary art world, how they change, integrate and develop, and evaluates the value of statistical thinking under the background of big data and the new form of contemporary art.
Love Lasts Forever: An Exploration of Love Based on Works of Art
Authors: Ma Margaret
Published: March 2023

Love, as one of the most universal emotions, is also an important theme in artistic creation. Artistic creation derives from love, and the huge tension from emotion and creation produces heart touching works. Love links the boundary between art and life. People can find the traces of love in the works of art, so as to move from loneliness to the rebirth of love. It can be said that art works freshen human love emotion, so that love can exist in personal life or human history. Based on the discussion about love in art works, this paper will explain the relationship between love and art from several aspects: Love is the original driving force of art, art works are the depiction and record of love, art works are the vague of love, and art makes love not be forgotten.
How to Present the Evolution of Visual Images in the Context of Digital Media Art
Authors: Song Zhouzhou
Published: March 2023

With the rapid development of digital media technology, the expression of images has also undergone great changes. Digital media has made the boundaries between different media clearer, and digital images have been expanded through digital media. However, due to the change of image expression form, it needs to be established on the basis of digital media. From the perspectives of the evolution of visual media and the development of image representation forms, this paper points out the role and development of media in images, as well as the representation forms and characteristics of images in various media.
Annotation Strategies in the English Translation of Contemporary Chinese Literary Works — A Case Study of "Red Sorghum"
Authors: Li Ze
Published: March 2023

Mo Yan's literary works have received wide attention in the world. "Red Sorghum" is his masterpiece. In order to let foreign readers understand the Chinese culture in the works, it is necessary to annotate and explain the corresponding words and sentences. In practical translation, literal translation with notes and free translation with notes can be adopted to help foreign readers better understand our culture. As for the conflicting contents, it is necessary to delete and replace them properly, so as to promote the acceptance of literary works by more readers abroad and promote the development of cultural works in China.
An Analysis of Montaigne’s Final Essay, Of Experience
Authors: Lu Bailin
Published: March 2023

In the final essay of Montaigne, named Of Experience, the author gave extensive criticism over the general misuse of judgement, while defining judgement quite peculiarly, which is that it is a faculty of the mind. How then, was this faculty that appears to be the rational part of the human mind but individuated from reasons defined by Montaigne? In what way do humans fail to properly utilize this faculty? What is the role of experience in the proper use of judgment? These questions shall be answered through a thorough analysis of this final work of the French thinker, through which we may find the form of the ideal that he looks to portray.
The Realistic Enlightenment of Chinese Excellent Traditional Culture in Labor Education
Authors: Han Tianwei
Published: March 2023

This paper intends to explain the practical enlightenment of Chinese excellent traditional culture in education on the hard-working spirit from three aspects, that is, the value of work is emphasized in Chinese excellent traditional culture, the tradition of farming-reading culture which advocates the combination of work and study is contained in Chinese excellent traditional culture, and the concept of "work for morality" is advocated in Chinese excellent traditional culture.