bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluasi Penggunaan Antibiotik pada Pasien Balita dengan Diagnosa Infeksi Saluran Pernapasan Atas di Puskesmas Koni Kota Jambi
Authors: Dewi Rasmala , Sutrisno Deny , Purnamasari Ryzki
Published: February 2022

Infeksi saluran pernapasan atas (ISPA) merupakan penyebab utama morbiditas dan mortalitas penyakit menular di dunia. Terapi pengobatan pada penyakit ISPA terdiri dari pemberian antibiotik dan pengobatan simtomatis. Penggunaan antibiotik yang tidak perlu atau berlebihan dapat mengakibatkan timbulnya resistensi terhadap bakteri tertentu. Resistensi tidak dapat dihilangkan, tetapi dapat dihindari atau diperlambat dengan penggunaan antibiotik secara rasional yang tepat dan bijak. Penelitian ini bertujuan untuk mengetahui kerasionalan penggunaan antibiotik pada pasien balita dengan infeksi saluran pernapasan atas di Puskesmas Koni Kota Jambi dengan parameter yang meliputi tepat pasien, tepat indikasi, tepat dosis, dan tepat durasi. Penelitian dilakukan pada 51 rekam medik pasien balita di Puskesmas Koni Kota Jambi di bulan Februari 2020-Maret 2020 secara retrospektif dengan teknik pengambilan data sampel secara purposive sampling dan kemudian dilakukan analisa data secara deskriptif. Berdasarkan 51 data rekam medik pasien balita di Puskemas Koni Kota Jambi Tahun 2019 masih ditemukan ketidakrasionalan dalam penggunaan antibiotik pada pasien ISPA. Rasionalitas penggunaan antibiotik pada pasien ISPA tahun 2019 berdasarkan analisa kualitatif yang telah dilakukan, didapat tepat pasien sebesar 100 %, tepat indikasi sebesar 100 %, tepat dosis sebesar 100 %, dan tepat durasi sebesar 0 %. Evaluasi ketepatan pasien, tepat indikasi dan tepat dosis dinyatakan tepat sedangkan evaluasi durasi pemberian antibiotik yang digunakan belum tepat.
Peranan Sel Limfosit Dalam Imunulogi: Artikel Review
Authors: Prakoeswa Flora Ramona
Published: February 2022

Lymphocytes are found in blood and lymph. Besides Natural killer (NK) cells, T cells and B cells are the different forms of lymphocytes. Each of these cells plays fundamental role in the body adaptive immune response. B lymphocytes are central players in the immune response; canonically, they have been recognized as precursors of antibody-producing cells: plasma cells. Recent findings have shown that the role of B lymphocytes goes far beyond the production of antibodies. There are different subtypes of B lymphocytes with different participations in innate and adaptive responses that include the recognition of the antigen, its processing, and its presentation to T lymphocytes, as well as the production of cytokines that impact and modulate the response toward the pathogen. Traditionally, it has been considered that B lymphocytes do not have phagocytic abilities that allow them to internalize, to process, or even to be infected by bacterial pathogens. The new information has shown that B lymphocytes can be readily infected by bacterial pathogens and respond to those infections. T lymphocytes play a role in cytotoxic immune responses. They belong to the adaptive immune system and perform a wide array of functions in immune regulation, inflammation and protective immune responses. In recent years, it has been shown that T cells are involved essentially across the entire spectrum of tissue physiology and pathology, not just in reactions or diseases considered to be bonafide immunological, but also, to cite just some examples, in metabolism, in tissue repair, in dysbiosis, and in pregnancy. Basic research on T cells has also sown the seeds that spawned the new era of immunotherapy that is engaging numerous researchers in finding a cure for cancer. The review of this article aims to further understand the latest findings regarding the formation and work mechanism of lymphocytes, especially on adaptive immunity. It summarizes the various forms of lymphocytes and their immunomodulatory roles in health and diseases.
Ce que cache l'eau : la darse de l'arsenal espagnol de Ferrol dans la seconde moitié du XVIIIe siècle
Authors: García Hurtado Manuel-Reyes
Published: February 2022

In the eighteenth century, with strong policy support for shipbuilding, arsenals appeared throughout Spain. This essay focuses on the Ferrol arsenal, the largest in Europe, and on its dock for it was in this maritime space that the fleet had to seek protection, thereby making it essential to provide the arsenal with specific accessibility and security considerations. To that end, technicians applied developments in hydraulic engineering but, while the construction of the arsenal was deemed a technological success, it also launched a debate, from an operational perspective, on how to make the best use of the dock.
PENTINGNYA MEMAHAMI PERBUATAN HUKUM TELEKOMUNIKASI DALAM KERJASAMA ANTARA PT. IM2 DENGAN PT. INDOSAT
Authors: Harsono Nonot
Published: February 2022

There is a difference between regulatory opinion of the Telecommunications Regulator/Ministry of Communications with the Corruption Court Judge on act did by PT. IM2 in collaboration with PT. Indosat. Title of cooperation between this service providers and network operators are "Internet access via cellular networks Indosat". In view of the regulator, this cooperation is in conformity with the regulations, even obligatory upon network operators to cooperate with the service provider. However, in view of the prosecutor and the judge, this cooperation violates the regulations. A difference of views between regulatory enforcement versus law enforcement is certainly very noteworthy because it will has very big impact to telecommunication development as the backbone of the national economy and the development of national legal systems and culture. Keywords: Networks, Network Usage, Frequency, Frequency Usage, Frequency Allocation, Frequency Allocation Usage
Hipotiroidismo causando ascite e elevação de marcador tumoral/CA- 125: um relato de caso
Authors: Moraes Júnior Rudival Faial de , Mesquita Ricardo Paulo Pereira , Silva Igor Martins Gonçalves , Santos Danielle Borborema Tolentino dos , Eugênio Natália Rodrigues , Miranda Yasaman Larissa Luyan Kós , Carvalho Pedro Arthur Ferreira de , Salvador Iasmin Rodrigues
Published: February 2022

Objetivo: Relatar o caso de uma paciente com ascite causada por hipotireoidismo associado com a elevação do marcador tumoral CA-125. Detalhamento do caso: Paciente feminina de 45 anos, com histórico de epilepsia secundaria a traumatismo crânio encefálico e de etilismo pesado em abstinência alcoólica há cerca de 3 meses foi encaminhada ao serviço de hepatologia da Fundação Santa Casa de Misericórdia do Pará para elucidação etiológica de ascite. Durante investigação, foram descartadas doenças hepáticas, neoplásicas e infecciosas, sendo observado TSH >100UI/ml com ascite refratária. Após a introdução da terapia hormonal com levotiroxina em doses mais elevadas com 75 mcg/dia, houve resolução do quadro clínico de ascite da paciente. Considerações finais: Este caso é notável, porque a ascite causada por hipotiroidismo é uma condição clínica rara. Sendo essa causa incomum de ascite, uma doença de fácil diagnóstico e tratamento, que deve ser pesquisada quando outras etiologias mais comuns não explicam o quadro clínico do paciente em questão.
Augmented Flap Reconstruction of Complex Pressure Ulcers Using Synthetic Hybrid-Scale Fiber Matrix
Authors: Vallery Mary , Shannon Thomas
Published: February 2022

Introduction. Flap reconstruction of pressure ulcers offers an important clinical means of decreasing morbidity in hospitalized patients. A new, novel method of managing pressure ulcer wounds uses a synthetic hybrid-scale fiber matrix prior to tissue flap reconstruction. This synthetic hybrid-scale fiber matrix is comprised of micron-scale and nanoscale fiber structure similar to that of human extracellular matrix and supports cell ingrowth, retention, and granulation tissue formation. Objective. The primary objective of the present study was to examine use of the synthetic hybrid-scale fiber matrix as a means of encouraging granulation tissue within complex wounds to promote successful and lasting wound closure following flap reconstruction. Materials and Methods. Patients included in this retrospective study had pressure ulcers that were not successfully managed with other wound therapies; in addition, these patients presented with various risk factors for postoperative complications. Before treatment, sharp debridement of the wound margins and wound bed was performed. Wounds were subsequently treated by applying synthetic hybrid-scale fiber matrix prior to flap reconstruction, based on physician assessment of wound status. The primary objective to include the synthetic hybrid-scale fiber matrix in the treatment approach of pressure ulcers in this case series was to ensure (1) integration to the wound bed prior to flap closure to encourage granulation tissue formation at a later time and (2) lasting successful wound closure following flap reconstruction. Results. Overall, the patient outcomes indicated that the synthetic hybrid-scale fiber matrix was used to manage pressure ulcers successfully, with a wound closure rate of 90.9% (10 cases of complete wound closure and 1 case of 97.2% wound area reduction). Additionally, no complication related to the application of each synthetic hybrid-scale fiber matrix was reported. Conclusions. Application of synthetic hybrid-scale fiber matrix to the wound bed prior to flap closure promotes cellular ingrowth and granulation tissue formation, which promotes successful and lasting wound closure following flap reconstruction.
Early Clinical Performance of an Adaptive Self-Assembling Barrier Scaffold in Nonhealing Chronic Wounds: A Review of Six Cases
Authors: Kapp Daniel , Pfendler Laura , D’Oro Lou , Wolcott Randall
Published: February 2022

Introduction. Chronic nonhealing wounds pose a serious concern for patient health and the health care system. Management of chronic wounds becomes especially challenging in the setting of systemic comorbidities and patient nonadherence. Objective. Authors evaluated the performance of a proprietary adaptive self-assembling barrier scaffold (aSABS) in the management and healing of complex chronic wounds. Materials and Methods. Six patients with anatomically and etiologically diverse chronic wounds were considered for treatment with aSABS, which is for prescription use under the supervision of a licensed health care professional. The wounds had been unresponsive to various treatment regimens for 8 weeks to more than 20 years. The adaptive self-assembling barrier scaffold was applied in the clinic weekly, with the exception of 1 case in which it was applied every 2 weeks. Institutional Review Board approval was not required because use of aSABS was in accordance with the US Food and Drug Administration-cleared indications for use. Results. After only 3 to 6 applications of aSABS, these wounds showed notable improvement in healing, accompanied by suppression of both inflammation and infection, granulation tissue formation, and reepithelialization. The adaptive self-assembling barrier scaffold also facilitated aggressive debridement to remove inflamed, infected, and necrotic tissues, providing effective wound management and bleeding control while functioning as a protective barrier. Furthermore, use of aSABS reduced the at-home burden of wound care for patients and caretakers. Additionally, use of this aSABS may offer clinicians an alternative to high acuity operating rooms by facilitating debridement and management of some complex wounds in a low acuity outpatient clinic setting—a particularly crucial product attribute during the COVID-19 pandemic that helped ensure timely and effective treatment. Conclusions. In this study, aSABS demonstrated clinical benefit in a short period of time in patients with significant comorbidities and nonhealing wounds. Use of aSABS may offer clinicians an alternative to high-acuity operating rooms by facilitating debridement and management of some complex wounds in a low-acuity outpatient clinic setting. These outcomes can be used to make a compelling argument for use of aSABS as a central aspect of treatment at the onset of wound care and as a rescue product for wounds for which prior standard and advanced treatment protocols were unsuccessful.
Role of Ultrathin Skin Graft in Early Healing of Diabetic Foot Ulcers: A Randomized Controlled Trial in Comparison With Conventional Methods
Authors: Shetty Rahul , Giridhar BS , Potphode Ankush
Published: February 2022

Introduction. Diabetic foot ulcers (DFUs) are a global burden on health care systems. Despite the availability of various treatment modalities, many DFUs do not heal. Nonhealing wounds can lead to various complications, which add to significant morbidity in terms of the degree of moisture retained in the dressing, pain, foul order, and restriction of daily activities. A different treatment modality that can promote the wound healing process earlier (and is cost-effective, easy to use, and readily available) may be necessary to consider. Objective. The purpose of the current study was to demonstrate the efficacy of ultrathin skin grafting (UTSG) in the early healing of DFUs in terms of cost-effectiveness, reduced total number of hospital visits, and final wound outcome (ie, limb salvage rate). Materials and Methods. A randomized controlled trial was conducted in which 52 patients were treated with either UTSG (test group) or conventional dressing (control group). Both groups were compared by time to healing, number of hospital visits, cost, and final outcome of the wound. Results. By the end of the 12-week study period, 84.61% of wounds managed with UTSG healed completely, whereas only 53.84% of wounds managed with conventional methods achieved complete healing. The test group achieved a more than 50% wound size reduction within 6 weeks after grafting. There were fewer hospital visits for the test group, indicating this grafting technique was more cost-effective than the control group. Conclusions. As demonstrated in this study, UTSG appears to be beneficial in achieving faster healing of DFUs and improving the final outcome of the wound.
Deep ContactlessS 3D-Middle Finger Knuckle Recognition
Authors: Surameery Nigar M. Shafiq
Published: February 2022

Automation security is one of the main concerns of modern times. A safe and reliable identity verification system is in great demand. A biometric verification system can represent a reliable method of identifying an individual. The knuckle pattern is considered to be one of the emerging hand biometrics because it has the potential to identify individuals. This presented work explores the possibility of using 3D middle finger knuckle for biometric identification. The study provides a new simple, trained from scratch but effective deep convolutional neural network model that designed for 3D figure knuckle print recognition. To the best of the author's knowledge, this is the first successful attempt to develop 3D middle finger knuckle based authentication system using Convolutional Neural Network (CNN). Extensive experiment was carried out using (HKPolyU) the 3D knuckle image database of Hong Kong Polytechnic University. The performance of the proposed CNN model has been evaluated using two session data obtained from different camera lenses. The model designed to be implemented in a real-time system. It can be deployed in a small-scale environment like offices, houses, or personal devices, where the training is very easy. The experimental results were very encouraging and showed the potential of using the 3D middle finger knuckle pattern for biometric applications. The results confirmed that despite various challenges compared with other studies in the same field, the proposed method provides an optimistic solution with an accuracy of 71%.
Palladium-Catalyzed Three-Component Selective Aminoallylation of Diazo Compounds
Authors: Ou Pengcheng , Zhu Lei , Yu Yinghua , Ma Liyao , Huang Xueliang
Published: February 2022

In spite of the valuable perspective on rapid accessing α,α-disubstituted α-amino acid derivatives, a three-component reaction of diazo compounds, amines and allyl esters remains as an unexplored challenge, probably because of the fore-seeable side reactions arising from each two reactants. In this work, we describe a novel Xantphos-containing dinuclear palladium complex enabled geminal aminoallylation of diazocarbonyl compounds, which provides a range of quaternary α-amino esters selectively. Direct N-H insertion, allylic alkylation of amino nucleophiles and diene formation were not observed under standard conditions. Mechanistic studies indicated that the Xantphos-containing palladium complex with a Pd/P ratio of 1/1 was optimal to enable the reaction to achieve high selectivity. A relayed pathway via allylation of N-H insertion product or [2,3]-sigmatropic rearrangement of a ylide intermediate was unlikely. We believe that the current strategy on palladium-catalyzed selective carbene difunctionalization could be general to construct quaternary carbon centers, and inspire more transformations in related field.
Development of small cyclic peptides targeting the CK2α/β interface
Authors: Atkinson Eleanor , Iegre Jessica , D'Amore Claudio , Brear Paul , Salvi Mauro , Hyvonen Marko , Spring David
Published: February 2022

CK2 is a ubiquitous protein kinase, with key roles in the regulation of cell growth and proliferation. In particular, CK2 acts as an anti-apoptotic protein and is found to be overexpressed in multiple cancer types. To this end, the inhibition of CK2 is of great interest with regard to the development of novel anti-cancer therapeutics. ATP-site inhibition of CK2 is possible; however, this typically results in poor selectivity due to the highly conserved nature of the catalytic site amongst kinases. An alternative methodology for the modulation of CK2 activity is to inhibit the formation of the holoenzyme complex. This is possible, with the most notable example being CAM7117. However, CAM7117 contains unnatural amino acids, residues not directly involved in the binding to CK2, and its size limits further optimisations. In this work, an iterative cycle of enzymatic assays, X-ray crystallography, molecular modelling and cellular assays were used to develop a functionalisable chemical probe for the CK2α/β PPI. The lead peptide, P8C9, successfully binds to CK2α at the protein-protein interaction site, is easily synthesisable and functionalisable, highly stable in serum and small enough to accommodate further optimisation. Furthermore, its cell-permeable analogues, TAT-P8C9 and R3-P8C9, successfully inhibit cell proliferation. TAT-P8C9 and R3-P8C9 can serve as true chemical probes to further understand the intracellular pathways involving CK2, as well as aiding the development of novel CK2 PPI inhibitors for therapeutic use.
A Prodrug Strategy for the In Vivo Imaging of Aldehyde Dehydrogenase Activity
Authors: Pereira Raul , Flaherty Renee , Edwards Richard , Greenwood Hannah , Shuhendler Adam , Witney Timothy
Published: February 2022

Therapy resistance is one of the biggest challenges facing clinical oncology. Despite a revolution in new anti-cancer drugs targeting multiple components of the tumour microenvironment, acquired or innate resistance frequently blunts the efficacy of these treatments. Non-invasive identification of drug-resistant tumours will enable modification of the patient treatment pathway through the selection of appropriate second-line treatments. Here, we have designed a pro-drug radiotracer for the non-invasive imaging of aldehyde dehydrogenase 1A1 (ALDH1A1) activity. Elevated ALDH1A1 activity is a marker of drug-resistant cancer cells, modelled here with matched cisplatin-sensitive and -resistant human SKOV3 ovarian cancer cells. The aromatic aldehyde of our prodrug radiotracer was intracellularly liberated by esterase cleavage of the geminal diacetate and specifically trapped by ALDH through its conversion to the charged carboxylic acid. Through this mechanism of action, ALDH-specific retention of our pro-drug radiotracer in the drug-resistant tumour cells was twice as high as the drug-sensitive cells. Acylal masking of the aldehyde afforded a modest protection from oxidation in the blood, which was substantially improved in carrier-added experiments. In vivo positron emission tomography imaging of tumour-bearing mice produced high tumour-to-background images and radiotracer uptake in high ALDH-expressing organs but was unable to differentiate between drug-sensitive and drug-resistant tumours. Alternative strategies to protect the labile aldehyde are currently under investigation.
A General Method for alpha-Functionalization of Enol Derivatives through the Umpolung Cross-Nucleophile Coupling Mediated by a Single Iodine(III) Reagent
Authors: García-Vázquez Victor , Carretero Cerdán Alba , Sanz-Marco Amparo , Gómez-Bengoa Enrique , Martín-Matute Belén
Published: February 2022

In this paper, we present an unprecedented and general umpolung protocol that allows the functionalization of silyl enol ethers and of 1,3-dicarbonyl compounds with a large range of heteroatomic nucleophiles, including carboxylic acids, alcohols, primary and secondary amines, azide, thiols, and also anionic carbamates derived from CO2. The scope of the reaction also extends to carbon-based nucleophiles. The reaction relies on the use of 1-bromo-3,3-dimethyl-1,3-dihydro-1delta3[d][1,2]iodaoxole, which provides a key alpha-brominated carbonyl intermediate. The reaction mechanism has been studied experimentaly and by DFT, and we propose formation of an unusual enolonium intermediate with a halogen-bonded bromide.
Kinetics observations of bacterial cellulose thickness formation using image
processing approach during the fermentation process
Authors: Nugroho D.A. , Sutiarso L. , Rahayu E.S. , Masithoh R.E.
Published: February 2022

Bacterial cellulose is an exopolysaccharide that has a higher level of purity compared to
cellulose from plants. Bacterial Cellulose (BC) is widely used for various uses so that it
requires certain initial conditions, one of which is thickness. During the fermentation
process, cellulose will be secreted into the medium to form BC sheets and visually visible
over the time period. The aim of this research was to study the relationship between
variables that influence during the fermentation and to fit the kinetic model of the BC
thickness formation using image processing approach during the fermentation process. A
USB camera was placed in front of the fermenter to capture the formation of BC
thickness. Python programming language was used to process the image and calculated
the thickness of the BC sheet from the beginning to the end of the fermentation process.
Several supporting parameters were observed by placing the turbidity, pH, and medium
temperature sensors. Observations were made in real time with a range of data collection
every 15 mins during fermentation. The highest correlation value was obtained from the
relationship between time and thickness. The fermentation process is divided into 2
clusters, a change in cluster occurs at the 61st hour. The model that describes the
relationship between time and thickness was the Gompertz model.
ELEMENTOS DA RATIO DECIDENDI: FATOS MATERIAIS, SOLUÇÃO JURÍDICA E MOTIVAÇÃO JUSTIFICATÓRIA
Authors: Guzansky Clívia Marcolongo Pereira
Published: February 2022

Este trabalho analisa a ratio decidendi, propondo-se, a partir do método dedutivo, equacionar a necessidade de homogeneização conceitual e funcional desse componente decisório tão sensível à teoria dos precedentes. Discutem-se o problema conceitual, o seu desenvolvimento na doutrina estrangeira e a proposta nacional de menção ao elemento determinante – eleito pelo legislador ordinário – como integrante do conceito de ratio, e, finalmente, apresenta-se a norma de julgamento como a soma dos elementos fático materiais, solução jurídica e motivação justificatória, que se pretende demonstrar imprescindível à renovação do direito jurisdicional ao passo das evoluções sociais, pela garantia de participação no processo decisório.
ACESSO AO PODER JUDICIÁRIO NA ERA DIGITAL: UMA ABORDAGEM SOBRE O IMPACTO DA TECNOLOGIA PARA PESSOAS QUE VIVEM NA POBREZA
Authors: Oliveira Natan Figueredo
Published: February 2022

Este artigo tem o propósito de analisar o impacto que as inovações tecnológicas nos serviços judiciários têm para o acesso à justiça das pessoas que vivem na pobreza. Traça uma definição de pobreza com base nas abordagens das “necessidades básicas” e “capacidades”. Investiga, por meio de pesquisa descritiva, qualitativa, de cunho bibliográfico, a relação da falta de acesso à internet e a equipamentos eletrônicoscom o acesso ao Poder Judiciário. Pondera-se, ao fim, comoas medidas de inclusão digital podemotimizar os serviços e alcançar as pessoas em situação de pobreza e, assim,democratizar o acesso à justiça.
EXCLUSÃO DIGITAL NO CONTEXTO PÓS-PANDÊMICO: DESAFIOS PARA A VIRTUALIZAÇÃO DA TUTELA JURISDICIONAL À LUZ DA RECOMENDAÇÃO-CNJ N.º 101, DE 12 DE JULHO DE 2021
Authors: Menegon Flávia Osmarin Tosti , Bellinetti Luiz Fernando
Published: February 2022

Analisa os principais contornos da Recomendação n.º 101/2021, do Conselho Nacional de Justiça, que determinou aos tribunais brasileiros a adoção de medidas específicas para a garantia de acesso à justiça dos chamados “excluídos digitais”. Tal perspectiva sobressai diante da virtualização dos serviços prestados pelo Poder Judiciário, ao longo da pandemia de COVID-19. Considera a possível política social que assegura, aos vulnerabilizados em âmbito tecnológico, auxílio mediante equipamentos e servidores ou, acaso não seja possível, a prática de atos processuais por meio não eletrônico. O método adotado será o dedutivo com base em análise de legislação e doutrina.
A DESJUDICILIZAÇÃO DA EXECUÇÃO CIVIL: UMA ANÁLISE DO PROJETO DE LEI 6.204/2019, COMO TÉCNICA RESOLUTIVA E INSTRUMENTO DE IMPLEMENTAÇÃO DA AGENDA 2030 E META 9 DO PODER JUDICIÁRIO
Authors: Curioni Rossana Teresa , Sayeg Ricardo Hasson
Published: February 2022

O presente trabalho tem por objetivo central de analisar a desjudiciliazação da execução civil, à luz do Projeto de Lei 6.204/2019, como um dos instrumentos de resolução da crise do Poder Judiciário, atuar minimizando as incalculáveis externalidades econômicas negativas para o desenvolvimento do País, na medida em que bilhões em créditos anuais deixam de ser satisfeitos, impactando diretamente o crescimento nacional, além de elevadíssimo custo da movimentação da máquina judiciária, que se mostra em conformidade com a segurança jurídica e a força obrigatória do cumprimento das obrigações
A GESTÃO DA INFORMAÇÃO EM EQUIPES VIRTUAIS NO PODER JUDICIÁRIO: desafios para uma comunicação eficiente e segura.
Authors: Da Costa Rafael Lima
Published: February 2022

A virtualização do Poder Judiciário impõe uma mudança cultural que impacte no planejamento estratégico dos processos internos de tratamento e compartilhamento de informações entre os membros das equipes virtuais. Este estudo busca verificar a existência de riscos oriundos dessa virtualização e se há a possibilidade de implantação de métodos e instrumentos para uma comunicação eficiente e segura. Foram realizadas revisão teórica e pesquisa quantitativa e qualitativa para abordagem multidisciplinar. Conclui-se que existem riscos decorrentes da falta de protocolos para o compartilhamento de informações, com a apresentação de proposições para minimizá-los.
HIPERTROFIA DO SUPREMO TRIBUNAL FEDERAL À LUZ DO PODER MODERADOR
Authors: Pereira Pérez Ricardo , Luduvice Cunha Ivan
Published: February 2022

A atuação do Supremo Tribunal Federal tem sido sucessivamente evidente na mídia e provocado inúmeras críticas, resultando no descrédito do Supremo Tribunal Federal. Além disso, tem-se questionado os limites da competência do Supremo, que tem agido como “poder moderador”. Todavia, o Poder Moderador era tido como um poder efetivo, objetivo e equilibrado. No presente artigo, por meio da pesquisa bibliográfica e do método indutivo, abordar-se-á o fundamento histórico do quarto poder e como este fora desvirtuado ao longo dos anos pela Corte Brasileira.
MANDATOS COLETIVOS E COMPARTILHADOS NO PODER LEGISLATIVO: potencialidades de inovação democrática e propostas de regulação.
Authors: Rossini Alexandre Montagna
Published: February 2022

Como inovação democrática, tem-se observado o expressivo crescimento das candidaturas coletivas ou compartilhadas em todas as regiões do país. Mediante uma pesquisa bibliográfica e descritiva, analisando as atuais propostas de regulação e algumas dessas experiências mais significativas, à luz do significado da palavra democracia, objetivou-se responder a duas questões principais: essas inovações democráticas têm potencial de mudança na participação política dos representados em relação aos mandatos legislativos de seus representantes, e consequentemente, potencial de mudança do cenário elitizado da política brasileira? E as atuais propostas de regulação atendem, facilitam ou dificultam a realização dessas potencialidades?
O CRIME DE CORRUPÇÃO ELEITORAL E O CONTROLE SOCIAL FORMAL: desafios para a construção de uma democracia real.
Authors: Guimarães Pedro Henrique , Guimarães Claudio Alberto Gabriel
Published: February 2022

A presente pesquisa se propõe, em uma perspectiva histórico-evolutiva, a analisar o contexto de surgimento e desenvolvimento do direito ao voto, para, então, examinar a conduta que se reputa ser a mais nociva ao direito de sufrágio em exame, a corrupção eleitoral. Assim, frente ao direito que se pretende resguardar e à sua vulnerabilidade, demonstra-se de que forma as personagens do controle social formal têm se posicionado frente às indesejáveis investidas daqueles que se propõem a negociar votos, dada a sua responsabilidade de combate e prevenção como modo de pôr em exercício a democracia substancial pretendida para a sociedade.
UMA POSSÍVEL PRECARIZAÇÃO DOS DIREITOS TRABALHISTAS, SOB A ÓTICA DO ADVOGADO ASSOCIADO, NOS LIMITES DA SECCIONAL DA BAHIA.
Authors: Santos Rafael Ribeiro , Oliveira Eric Araujo
Published: February 2022

O presente estudo utiliza como alicerce fundamentador uma pesquisa feita pela comissão especial dos advogados/as associados da seção do Estado da Bahia. Serão analisados também se os instrumentos jurídicos que regulamentam a tipologia jurídica do contrato de associação são respeitados, se os advogados entrevistados sofrem subordinação, se recebem de acordo com a efetiva partilha de resultados, se a carga horaria laboral máxima explicitada pela constituição é respeitada e se recebem contraprestação remuneratória condizente com o exercício profissional. Adotou-se, como método de pesquisa o dedutivo e a leitura qualitativa através da pesquisa: “relatório da comissão especial dos advogados/as associados”.
DA DEFINIÇÃO DA ESCRAVIDÃO DE ACORDO COM A CORTE INTERAMERICANA DE DIREITOS HUMANOS À LUZ DO CASO TRABALHADORES DA FAZENDA BRASIL VERDE Vs. BRASIL
Authors: Loiola Rodrigo Rocha Gomes de , Pereira Francisco José Rocha
Published: February 2022

Objetiva-se neste artigo, analisar a sentença da Corte Interamericana de Direitos Humanos (CtIDH) que se debruçou sobre o assunto ao tratar do caso Trabalhadores da Fazenda Brasil Verde vs. Brasil. Tem-se, como pergunta de pesquisa, a seguinte: o que a CtIDH entende como escravidão? Foram adotadas abordagens variadas de pesquisa qualitativa, a partir de revisão bibliográfica disponível sobre o tema. Conclui-se que a escravidão é forma de exploração que rouba a dignidade do trabalhador, muitas vezes mediante o cerceamento da liberdade.
A LEI N° 14.126/2021 E O ENQUADRAMENTO DA VISÃO MONOCULAR COMO DEFICIÊNCIA VISUAL PARA FINS PREVIDENCIÁRIOS, ASSISTENCIAIS E TRIBUTÁRIOS
Authors: Alves de Paula Ana Cristina , Piva Almeida Leite Flávia
Published: February 2022

No dia 23 de março de 2021 foi sancionada a Lei n° 14.126/2021, que estabeleceu que a classificação da visão monocular como deficiência sensorial, do tipo visual, para todos os efeitos legais. Este artigo se propõe a debater as garantias estendidas às pessoas com visão monocular pela mencionada legislação, debatendo em que consiste tal condição, se é considerada deficiência ou não, quais são os direitos de quem a possui e o que diz a jurisprudência mais recente sobre o tema, adotando o método dedutivo e a técnica de pesquisa bibliográfica.
A (IN)VISIBILISADE DO MENOR SOB GUARDA E A PENSÃO POR MORTE
Authors: Bittencourt Renata Osório Caciquinho , Borsio Marcelo Fernando , Pires Luiz Henrique Paiva
Published: February 2022

A proteção social do menor sob guarda no cenário Brasileiro, em análise dos fluxos e refluxos legislativos entremeados a polêmica dos antagônicos argumentos são o objeto da presente pesquisa, desenvolvida pelo método teórico propositivo. Justifica-se a relevância a partir da necessidade de análise (in)conformidade da legislação posta com as Garantias Constitucionais com o objetivo de verificar o alinhamento a busca da Justiça Social delineada por John Rawls. Conclui-se que, mesmo com a decisão do STF garantindo a proteção social ao menor sob guarda, a persistência da polêmica demonstra a necessidade de uma profunda mudança cultural paradigmática.
O CONSUMO DE ALIMENTOS ULTRAPROCESSADOS E SUA DIVULGAÇÃO, INCLUINDO PUBLICIDADE DIRECIONADA À CRIANÇA: DIREITO BRASILEIRO E DIREITO INTERNACIONAL
Authors: Prux Oscar Ivan , Gonçalves Marina Weiss
Published: February 2022

O presente artigo examina questões relacionadas ao mercado de alimentos ultraprocessados cujo direcionamento visa o consumo primordialmente por parte de crianças, considerando sua hipervulnerabilidade, seus direitos fundamentais e da personalidade envolvidos. Destaca a questão da oferta desses alimentos (publicidade explícita e implícita), seu consumo pelos menores e consequências das relações de consumo dessa ordem. Sem olvidar legislação internacional à qual faz referência, em nível nacional o trabalho fundamenta-se no conteúdo do sistema de proteção ao consumidor (Lei nº 8.078/90, Lei n° 8.069/90 e normas regulamentares). Baseia-se, para tanto, em pesquisas bibliográficas e vale-se do método hipotético dedutivo para confecção.
A DEFESA DO CONSUMIDOR NAS RELAÇÕES DE E-COMMERCE PELO FOMENTO À PROTEÇÃO DOS DADOS PESSOAIS SENSÍVEIS NA SOCIEDADE DA INFORMAÇÃO
Authors: Souza Devanildo De Amorim , Terzidis Cristina Anita Schumann Lereno
Published: February 2022

Este artigo procura analisar, com base na análise bibliográfica, apresentando-se através do método jurídico dogmático dedutivo, os direitos da personalidade de forma ampla, seu respaldo perante a Constituição da República Federativa do Brasil de 1988 e sua aplicabilidade perante o Código de Defesa do Consumidor, assim como na lei 13.709/18, tendendo resguardar os direitos intrínsecos ao ser humano perante as relações de consumo. Visa abordar também, o tratamento de dados pessoais e de dados pessoais sensíveis perante a legislação 13.709/18, no contexto protetivo legal.
A EXIGIBILIDADE DA TENTATIVA PRÉVIA DE RESOLUÇÃO DO CONFLITO E O ACESSO DO CONSUMIDOR À JUSTIÇA À LUZ DOS PRECEDENTES DO SUPREMO TRIBUNAL FEDERAL
Authors: Elesbon Salomão Akhnaton Zoroastro Spencer
Published: February 2022

O presente artigo investiga a exigibilidade da comprovação da pretensão resistida, como filtro ao ajuizamento de demandas pelo consumidor, à luz da jurisprudência do Supremo Tribunal Federal. A hipótese é que essa exigência sofre limitações pelo objeto do litígio e pela capacidade de atendimento efetivo e tempestivo da pretensão na via extrajudicial. A metodologia consiste na pesquisa bibliográfica e análise aprofundada do Recurso Extraordinário nº 631.240/MG, da Ação Direta de Inconstitucionalidade nº 2.139/DF e julgamentos a eles conexos. Validada a hipótese, propõe-se a aplicação da ratio decidendi desses julgados às demandas do consumidor.
SUPERENDIVIDAMENTO E DIREITOS FUNDAMENTAIS: Lei n° 14.181/2021 e o direito ao mínimo existencial.
Authors: Gonçalves Clayrtha Raissa , Pereira Paulo Sérgio Velten
Published: February 2022

Estuda-se a relação do superendividamento do consumidor e os Direitos Fundamentais, ressaltando o Estado de Direito e o pensamento sistemático do ordenamento jurídico. Discorre sobre regras e princípios de Direitos Fundamentais para visualizar o tratamento do superendividamento pelas Instituições do Sistema de Justiça, previsto na Lei n° 14.181/2021. Metodologicamente, por abordagem dedutiva, analisa-se o critério de mínimo existencial previsto na lei do Superendividamento, como condição ao consumidor de boa-fé. A referida lei dispõe sobre a prevenção e tratamento ao superendividamento. Conclui-se pela importância da consideração dos Direitos Fundamentais para fixação dos critérios de mínimo existencial.
RESPONSABILIDADE SOCIAL DA EMPRESA, PANDEMIA E O DIREITO BRASILEIRO ENTRE LIBERDADE E SOLIDARIEDADE
Authors: Oliveira Francisco Cardozo , Gunther Luiz Eduardo
Published: February 2022

O artigo faz análise dos fundamentos sociais e jurídicos das ações de responsabilidade social das empresas no contexto da pandemia do Covid-19 no Brasil, e no confronto entre tutela da liberdade e promoção da solidariedade.  Desde uma perspectiva jusfilosófica, investiga-se o alcance da normatividade das ações de responsabilidade social mediante estratégias de regulação jurídica e de compromissos éticos e morais assumidos pelas empresas.  A análise aponta para uma situação em que o desenvolvimento de ações de responsabilidade social pelas empresas no Brasil não observa o eixo de conexão entre tutela da liberdade social e promoção da solidariedade.
AS FUNÇÕES DA INFORMAÇÃO NO MERCADO DE VALORES MOBILIÁRIOS E SUA DIVULGAÇÃO OBRIGATÓRIA: ANÁLISE DE DECISÕES JUDICIAIS SOBRE A RESPONSABILIDADE CIVIL DA COMPANHIA ABERTA POR VIOLAÇÕES DO DEVER DE INFORMAR
Authors: Ferreira de Assumpção Alves Alexandre , Villela Mafra Alves da Silva Ricardo
Published: February 2022

O artigo tem por objetivo examinar o dever de informar da companhia aberta e as funções da informação no mercado de valores mobiliários a partir de 4 decisões judiciais em que se discutiu a responsabilidade civil da companhia perante investidores por falhas informacionais. Adotou-se o método científico indutivo, modo a extrair conclusões dos casos concretos, a partir de pesquisa documental e bibliográfica. Como contribuição, sustenta-se que as decisões analisadas podem viabilizar a construção de uma jurisprudência sobre o dever de informar da companhia assentada na aplicação das normas societárias e do mercado a partir das funções exercidas pela informação.
A mechanical model and stress-strain response of the biceps brachii under static load
Authors: DERESHGI Hamid Asadi , SERBEST Kasım , ŞAHİN Sema Nur , BALIK Büşra
Published: February 2022

Muscle contraction is a complex phenomenon that begins with chemical processes, continues physiologically, and leads to the production of force. Although the production of force in the muscles depends on factors such as temperature, age, gender, race, but the most important factor is the external load applied to the muscle. Determining the effects of increased load on muscle mechanics is of particular importance for planning exercise activities and rehabilitation processes. In this study, the effects of different external forces on the stress and pressure behavior of the muscle were examined on a simplified model of the biceps. Accordingly, a finite element model of the biceps brachii muscle fiber was constructed. The application of different static loads (2.5 – 100 N) on both the proximal tendon (one-directional) and the proximal and distal tendon (bidirectional) together were investigated. According to the results, it was found that the external force applied in both directions causes a significant increase in displacement behavior and stress.
Effect of repair parameters on composite plates under low velocity impact
Authors: ALBAYRAK Mustafa , GÜR Mustafa , KAMAN Mete Onur
Published: February 2022

In this study, the impact behavior of patch-repaired layered composite plates under low velocity impact loads was numerically investigated. For this purpose, layered composite plates with holes with different geometries in the middle were repaired with patches using various adhesives. Impact behavior of the composite material was investigated by dropping the strikers with different speeds on the repaired composite plate. Layered composite plate was used as the sheet and patch material, and the orientation angles are [0 ° / 45 ° / 45 ° / 0 °] for the plate and [0 ° / 45 °] for the patch. ANSYS Ls-Dyna finite element package program was used for three dimensional modelling and solution. Therefore, the effects of variables such as striker, adhesive, plate and patch on the impact behavior of layered composite material were investigated for different boundary conditions. It has been determined that the hexagonal patch type performs better than other patch geometries.
Analisis Konstanta Pegas pada Fondasi Tiang (Studi Kasus: Gedung Type B DPRD Surabaya)
Authors: Yakin Yuki Achmad , Pratiwi Desti Santi , Bilaldy Berry Fawaz
Published: February 2022

ABSTRAKKonstanta pegas tanah (k ) merupakan suatu hubungan konsep pengertian di antara tekanan tanah dan defleksi. Nilai konstanta pegas sudah banyak digunakan di dalam analisis konstruksi bagian-bagian fondasi. Nilai  dipakai untuk menghitung besarnya reaksi pada kepala tiang atau besarnya penurunan elastis pada pondasi. Konstanta pegas pada tanah terdiri dari dua arah, yaitu arah vertikal dan arah horizontal. Pada penelitian ini akan dilakukan analisis perhitungan nilai  pada lapisan tanah pasir dan lempung menggunakan Program Lpile dan Allpile. Perhitungan nilai k  untuk arah horizontal dilakukan menggunakan metode kurva p-y (Program Lpile) sedangkan untuk arah vertikal menggunakan metode kurva t-z  (Program Allpile). Nilai k  yang didapatkan dari kurva p-y dan kurva t-z akan dibandingkan dengan metode konvensional yang biasa digunakan. Hasil analisis menunjukkan bahwa nilai k  arah horizontal dengan metode p-y lebih besar dibandingkan dengan konvensional, sedangkan nilai k  arah vertikal hasil metode t-z  lebih kecil dibandingkan dari metode konvensional.Kata Kunci: konstanta pegas tanah, N-SPT, kurva , kurva , Allpile, Lpile ABSTRACTThe soil spring constant (k ) is a correlation concept between soil pressure and deflection. The value of spring constant has been widely used in the analysis of foundation parts. The value is used to calculate the magnitude of the reaction at the pile head or elastic settlement in the foundation. Soil spring constant consists of two directions, vertical direction and horizontal direction. This research will analyze the calculation of the  value on sand and clay sil layers using Lpile and Allpile Program. Calculation of the  value for the horizontal direction was used the p-y curve methode (Lpilee Program), while for the vertical direction used the t-z cuve method (Allpile). The k values obtained from the p-y curve and th t-z curve will be compared with convntional methiods. The analysis results show that the horizontal k value with the  p-y method is greater than the conventional method, while the value in the vertical direction from the t-z method is smaller than the conventional method.Key Words: soil spring constant, N-SPT,  p-y curve, t-z curve, Allpile, Lpile
The German Doctrine of “Realpolitik” Through the Prism of Modern World Politics
Authors: Zubov V. V.
Published: February 2022

The proposed paper examines the problem of updating the German doctrine “Realpolitik” in relation to contemporary world politics. The presentation of the material follows a theoretical and methodological line, associated with the designation of the main approaches to “real politics” that were present in the history of political thought. Secondly, it compares the realistic direction of political science analysis with the normative-value paradigm and a practice-oriented line, associated with an appeal to the current world political agenda and the characteristics of those directions that have political realism as a fundamental principle. When referring to real-world politics, the author concluded that realism is especially relevant in the following areas: reducing the nuclear arsenal and weakening the missile potential, preventing the deployment of strategic offensive weapons and the deployment of armed forces of competing militarypolitical blocs in border areas, the fight against international terrorism, as well as preventing the consequences of the new coronavirus pandemic.
War as a katálysis of Ideas. The Philosophical Concept of Dmitry Merezhkovsky during the First World War
Authors: Vanchyk D.
Published: February 2022

This article analyses the impact of the First World War on the evolution of the philosophical worldview and especially on the historiosophical idea of Dmitry Merezhkovsky’s theocratic anarchy. According to the author, the war is seen here as a katálysis, due to which the division, exposition, and radicalization of the constitutive elements of this concept takes place. Through the analysis of texts 1914–1917. Merezhkovsky’s attitude to such key concepts as war, revolution, intelligentsia, religion, violence, patriotism, nationalism, universalism, neo-Slavophiles, and the authors of the almanack “Milestones” is determined.
The US Energy Policy Strategy as an Instrument for the Struggle Between Republicans and Democrats in the Election Race
Authors: Zhukova L. V.
Published: February 2022

In this article, the author analysed the cause of massive rolling blackouts in the USA, Texas and followed the change of people’s opinions regarding the country’s energy policy. The results show that extreme freezing temperatures had a more significant impact on Texas Republicans in comparison with the Democrats and Grand Old Party (GOP) average. Meeting with the reality of power outages caused by cold weather in Southern State is the reason why Texas Republicans are far more supportive of specific climate policies than most other Republicans. Meanwhile, according to the author, both Parties have tremendous opportunities to use unplanned blackouts in the political struggle because, supported by Biden’s Democratic Program, wind farms are guilty and Republican’s fossil fuels.
Contradictions in Comprehending the Beginning of Russian Statehood in the Aspect of Various Social Projects
Authors: Kalney M. S .
Published: February 2022

The goals and objectives of the study are to compare different ideas about historical knowledge in the aspect of legitimizing the social system, to compare the main characteristics of social projects and their approaches to understanding the beginning of Russian statehood. The study used the methods of comparative analysis when examining the object in all its interrelationships and contradictions. Also, the author used the ascent from the abstract to the concrete in the unity of the historical and logical approaches. The author refers to the description of the nature of social myth in the works of J. Frazer, A. F. Loseva, E. Fromm, who analyses the views of the social reality of domestic and foreign researchers. The work results continue and develop the discussion about the foundations of Russian statehood, presented in the works of various authors. The study allows for a comparative analysis of various social projects, the degree of their utopianism, and, consequently, their viability and feasibility.