bluuebunny/crossref_metadata_2025 huggingface dataset:
A cross-national study of family-friendly policies, gender egalitarianism, and work–family conflict among working parents
Authors: Hsiao Hsinyi
Published: September 2023

Social policies impinge on daily lives of individuals and affect how they negotiate work and family demands. To fill in the void in the international work–family literature regarding whether public family-friendly policies effectively decrease work–family conflict the present study examined multilevel effects of family-friendly policies, organizational type, and family characteristics on working parents’ work–family conflict by gender using random samples of 6,878 individuals in 24 countries in Africa, Asia, Europe, and North and South America. Drawn on role stress theory, gender egalitarianism, and institutional theory this study showed that parental leave policies have greater influence on work–family conflict among men compared to women. Individual dimensions of parental leave policies on men’s experience of work–family conflict impinged on workplace characteristics and family characteristics. Implementing parental leave policies with high flexibility and higher rates of income replacement may help men with working spouses or who are employed in the public sector to reduce bidirectional conflicts between work and family. Women generally were not protected by individual dimensions of parental leave policies. Instead, societal attitudes towards gender played a key role in helping women reduce bidirectional conflicts between work and family roles.
Global risk factor analysis of myopia onset in children: A systematic review and meta-analysis
Authors: Yu Mingkun , Hu Yuanyuan , Han Mei , Song Jiawei , Wu Ziyun , Xu Zihang , Liu Yi , Shao Zhen , Liu Guoyong , Yang Zhipeng , Bi Hongsheng
Published: September 2023

Introduction

This work aimed to comprehensively assess the risk factors affecting myopia in children to develop more effective prevention and treatment strategies. To this end, data from database were employed to assess the relationship between the incidence of myopia and its risk factors.

Methods

We searched eight databases online in June 2022. Cohort studies were included that measured the connection between risk factors and myopia. Eligibility was not restricted by language. The Newcastle–Ottawa Scale (NOS) was used to measure the risk of bias and conducted GRADE evaluation to determine the certainty of evidence. Potential risk factors with positive or negative results were seen. Inplasy Registration: https://inplasy.com/inplasy-2022-4-0109/.

Results

Evidence that risk factors for myopia are mixed, comprising both positive (20) and null (17) findings. In 19 cohort studies on 3578 children, girls were more likely to develop myopia (RR: 1.28 [1.22–1.35]). Myopia can occur at any age, from early childhood to late adulthood. Children whose parents had myopia were more likely to develop myopia. Longer outdoor activities time (RR: 0.97 [0.95–0.98]) and less near-work time (RR: 1.05 [1.02–1.07]) appeared to be significantly decrease the incidence of myopia. Children with lower SE, longer AL, a lower magnitude of positive relative accommodation, worse presenting visual acuity, deeper anterior chamber, and thinner crystalline lens may be related to myopia onset. The burden of myopia in underprivileged countries is higher than in developed countries (RR: 5.28 [2.06–13.48]). The quality of evidence for the evaluated factors was moderate to low or very low.

Conclusions

Genetic factors, environmental factors (such as excessive use of electronic products, and poor study habits) and lifestyle factors (such as lack of outdoor activities, poor nutrition, etc.) are the main risk factors for myopia in children. Myopia prevention strategies should be designed based on environmental factors, gender, parental myopia and eye indicators in order to explore a lifestyle that is more conducive to the eye health of children.
Identifying SNP markers associated with distinctness, uniformity, and stability testing in Egyptian fenugreek genotypes
Authors: Abd El-Wahab Mustafa M. H. , Abdel-Lattif Hashim , Emara Kh. S. , Mosalam Mohamed , Aljabri Maha , El-Soda Mohamed
Published: September 2023

Distinctness, uniformity, and stability (DUS) test is the legal requirement in crop breeding to grant the intellectual property right for new varieties by evaluating their morphological characteristics across environments. On the other hand, molecular markers accurately identify genetic variations and validate the purity of the cultivars. Therefore, genomic DUS can improve the efficiency of traditional DUS testing. In this study, 112 Egyptian fenugreek genotypes were grown in Egypt at two locations: Wadi El-Natrun (Wadi), El-Beheira Governorate, with salty and sandy soil, and Giza, Giza governorate, with loamy clay soil. Twelve traits were measured, of which four showed a high correlation above 0.94 over the two locations. We observed significant genotype-by-location interactions (GxL) for seed yield, as it was superior in Wadi, with few overlapping genotypes with Giza. We attribute this superiority in Wadi to the maternal habitat, as most genotypes grew in governorates with newly reclaimed salty and sandy soil. As a first step toward genomic DUS, we performed an association study, and out of 38,142 SNPs, we identified 39 SNPs demonstrating conditional neutrality and four showing pleiotropic effects. Forty additional SNPs overlapped between both locations, each showing a similar impact on the associated trait. Our findings highlight the importance of GxL in validating the effect of each SNP to make better decisions about its suitability in the marker-assisted breeding program and demonstrate its potential use in registering new plant varieties.
Roles of the interaction with children and families in mediating the association between digital health literacy and well-being of early childhood teachers in Portugal: A cross-sectional study
Authors: Rosário Rafaela , Barros Araújo Sara , Silva Ana , Barros Sílvia
Published: September 2023

Aim

To analyze the associations between early childhood education (ECE) teachers´ digital health literacy (DHL) and well-being, and to determine whether the ECE teachers´ interaction with children and family mediated these associations.

Methods

A total of 853 early childhood teachers, predominantly women (99.4%) participated in this cross-sectional study. The participants had a mean age of 39.9 years (standard deviation SD = 8.2). Data was collected through an online survey. DHL was assessed using five subscales adapted to the new coronavirus context, and the professionals´ well-being was measured using the WHO-5 well-being scale. Binary logistic regression and mediation analysis were used to analyze the data.

Results

ECE teachers’ DHL in dimensions of “information searching” and “determining relevance” had both direct and indirect effect on their well-being. Specifically, higher DHL in these dimensions was associated with better well-being. The dimension “evaluating reliability” had an indirect positive effect on well-being by promoting interaction with children.

Conclusion

These findings suggest that improving ECE teachers´ DHL could have a positive effect on their well-being and their interactions with children. Therefore, it is recommended to develop health promotion practices aimed at enhancing DHL among ECE teachers. Additionally, integrating DHL contents and competencies more prominently into the qualification, further education and training of ECE teachers may help equip them with the necessary skills to access and apply health information effectively. This, in turn, can enhance interactions with children and contribute to their overall well-being.
Clinical and financial outcomes of hospitalizations for cardiac device infection during the COVID-19 pandemic in the US
Authors: Ascandar Nameer , Chervu Nikhil , Bakhtiyar Syed Shahyan , Cho Nam Yong , Kim Shineui , Orellana Manuel , Benharash Peyman
Published: September 2023

Background

Cardiac device infection (CDI) can occur in up to 2.2% of patients after device placement, with mortality rates exceeding 15%. Although device removal is standard management, the COVID-19 pandemic has been associated with resource diversion and decreased patient presentation for cardiovascular disease. We ascertained the association of the COVID-19 pandemic with outcomes and resource utilization after admission for CDI.

Methods

The 2016–2020 National Inpatient Sample was used to retrospectively study all adult admissions for CDI. Patients admitted between March and December, 2020 were classified as the pandemic cohort, with the rest pre-pandemic. The primary outcome was major adverse events (MAE), with secondary outcomes of overall length of stay (LOS), post-device removal LOS, time to device replacement, and hospitalization costs. MAE was a combination of in-hospital mortality and select complications. Multivariable regression models were developed to determine the relationship between the pandemic and the aforementioned outcomes.

Results

Of an estimated 190,160 patients, 14.3% comprised the pandemic cohort; 2.4% of these patients were COVID-19 positive. The pandemic cohort was older, less commonly female, and had higher rates of congestive heart failure. After adjustment, the pandemic was not associated with altered odds of MAE, device removal, or subsequent device replacement. The pandemic was, however, associated with decreased adjusted overall LOS (β -0.38 days) and days to device replacement (β -0.83 days). The pandemic was likewise associated with $2,000 increased adjusted hospitalization costs.

Conclusion

The pandemic did not have a significant impact on clinical outcomes in patients admitted for CDI, despite higher hospitalization costs and decreased length of stay.
Minimal clinically-important differences for the “Liverpool Osteoarthritis in Dogs” (LOAD) and the “Canine Orthopedic Index” (COI) in dogs with osteoarthritis
Authors: Alves J. C. , Innes John F.
Published: September 2023

Objective

Osteoarthritis is the most common joint disease in companion animals. Several client-report outcome measures (CROMs) have been developed and validated to monitor patients and their response to treatment. However, estimates for minimal clinically-important differences for these CROMs in the context of osteoarthritis have not been published.

Patients and methods

Data from the Clínica Veterinária de Cães (Portuguese Gendarmerie Canine Clinic) clinical records were extracted. Baseline and 30-day post-treatment follow-up data from 296 dogs treated for hip osteoarthritis were categorized based on an anchor question, and estimates of minimal clinically-important differences (MCIDs) using distribution-based and anchor-based methods were performed.

Results

For the LOAD, the anchor-based methods provided a MCID estimate range of -2.5 to -9.1 and the distribution-based methods from 1.6 to 4.2. For the COI, the anchor-based methods provided a MCID estimate range of -4.5 to -16.6 and the distribution-based methods from 2.3 to 2.4. For the dimensions of COI, values varied from -0.5 to -4.9 with the anchor-based methods and from 0.6 to 2.7 with the distribution-based methods. Receiver operator characteristic curves provided areas under the curve >0.7 for the COI, indicating an acceptable cut-off point, and >0.8 for the LOAD, indicating an excellent cut-off point.

Conclusion

Our estimates of MCIDs for dogs with OA were consistent with previously proposed values of -4 for the LOAD and -14 for the COI in a post-surgical intervention context. ROC curve data suggest that LOAD may more reliably differentiate between anchor groups. We also presented estimates from COI of -4 for Stiffness, Function, and Gait and -3 for quality of life. These estimates can be used for research and patient monitoring.
Predictive factors and prognosis of upper gastrointestinal bleeding in gastric cancer: A large population-based study (UGIB-GC trial)
Authors: Kiattiweerasak Anya , Bongkotvirawan Phubordee , Aumpan Natsuda , Yamaoka Yoshio , Miftahussurur Muhammad , Vilaichone Ratha-korn
Published: September 2023

Background

Gastric cancer remains the fourth leading cause of cancer-related death worldwide. Significant number of gastric cancer patients presented with bleeding.

Objective

This study aimed to identify risk factors and overall survival rates of bleeding gastric cancer patients.

Methods

This retrospective cohort study was conducted between 2007–2022 at tertiary care center in Thailand. Clinical information, endoscopic findings and histological type were extensively reviewed and were compared between bleeders and non-bleeders. Patients were monitored for at least 5 years.

Results

There were 20,981 patients who underwent upper gastrointestinal endoscopy during study period. Total of 201 gastric cancer patients were included in this study, 21 were excluded due to incomplete medical records. 180 gastric cancer patients were included with mean age of 60.5±14.3 years. There were 65 (36.1%) patients with gastrointestinal bleeding. Hypertension and chronic kidney disease were significantly more common in bleeders than non-bleeders (43.1% vs 23.5%, OR2.51, 95%CI 1.14.-5.52, p = 0.022; and 16.9% vs 5.2%, OR2.00, 95%CI 1.56–6.63, p = 0.025, respectively). current H. pylori infection was also significantly more common in bleeders than non-bleeders (84.6% vs. 55.7%, OR 4.39, 95%CI 1.90–10.12, p<0.001). Median overall survival of bleeders was significantly lower than non-bleeders (7±0.93 vs 10±2.10 months, p = 0.001).

Conclusions

Bleeding gastric cancer was not an uncommon condition. Majority of patients presented at advanced stage with grave prognosis. Male gender, hypertension, chronic kidney disease, and current H. pylori infection were reliable predictors for bleeding. Early diagnosis and prompt treatment are the key to improve clinical outcome.
Hybrid Quantum Algorithms and Quantum Software Development Frameworks
Authors: Ramouthar Ravindra , Seker Huseyin
Published: September 2023

The choreography of quantum mechanical phenomena has catalysed accelerated advances in the emergence of a quantum computational substrate paradigm that yields the potential to solve some of humanities most complex problems through quantum computing speedup requires exponential computational power that exceeds that of today’s most powerful super-computers, to confront the world’s most intractable computational challenges in environment, agriculture, health, energy, climate, materials science, precision medicine, autonomous vehicles in smart cities, renewable energy and problems humanity has not yet even imagined. Current quantum computational substrates are limited by circuit depth, noise processes, qubit count, and fault tolerant quantum computational substrates unlikely to be available in the near term. Hybrid quantum algorithms/Variational Quantum Algorithms (VQAs), operate by using a classical optimizer to orchestrate the parameters of a quantum circuit, have become a prominent approach to address these limitations. However, several challenges manifest that include the training, speedup. accuracy, and impactful practical application of VQAs. This paper reviews novel new frontiers in current VQAs, provides an analysis of VQAs, their strengths and limitations, and outlines potential applications in the quest towards yielding practical quantum advantage. Secondly, this paper also reviews and provides an assessment of quantum software development frameworks.
Varicocele Secondary to Splenic Vein Compression by Intragastric Balloon
Authors: Alangari Abdulrahman , Alamri Musab , Semaan Toufic , Hafez Ihab , Alruzug Ibrahim
Published: September 2023

Intragastric balloons (IGBs) are commonly used for weight loss by mechanically distending the stomach. We present a case of a 35-year-old man who developed a left-sided varicocele 1 week after IGB insertion. Imaging revealed splenic vein compression and possible thrombosis. Urgent removal of the balloon was performed. After 1 week from removal, the patient showed significant improvement, with complete splenic vein recanalization. This case highlights the importance of early recognition of a rare complication of IGBs to avoid severe outcomes. To our knowledge, this is the first reported case linking IGBs to splenic vein compression and varicocele.
Hermenéutica del lenguaje desde la perspectiva sociocultural
Authors: Abad Salgado Ana María
Published: September 2023

Objetivo: Este artículo propone develar la hermenéutica del lenguaje implícita en la concepción de las realidades socioculturales, con el fin de reconocer sus principales configuraciones. Metodología: A partir de una revisión Teo? Rica se demarcan tópicos conceptuales desde la visión epistémica de la hermenéutica del lenguaje en el marco sociocultural. Hallazgo: Existen realidad- des socioculturales complejas cognoscibles - siempre de manera provisional, y la hermenéutica del lenguaje constituye una base de lectura para develar las estructuras y el funcionamiento de dicha complejidad —construida desde el principio de sistema—, donde la realidad tematizada es entorno y, desde el principio de circularidad sistémica, los cambios en un subsistema impactan a los demás y, por ende, a los otros entornos; lo que aumenta la complejidad social y acentúa los discursos hegemónicos establecidos. Conclusión: La hermenéutica del lenguaje desde sus constructos teóricos y fundamentos metodológicos permite develar la complejidad de los procesos socioculturales, evidenciando que la realidad misma siempre será? más compleja que los modelos teóricos que se establecen para comprenderla.
Effect of the non-uniform combustion core shape on the biochar production characteristics of the household biomass gasifier stove
Authors: Chaiyalap Somchet , Chai-ngam Ritthikrai , Saengprajak Juthaporn , Piamdee Jenjira , Putkham Apipong , Saengprajak Arnusorn
Published: September 2023

The global demand for biochar in agricultural and carbon sequestration applications is increasing; nevertheless, biochar production using the 50-liter household biomass gasifier stove (50L-HBGS) in Thailand found major issues that need to be improved. The objective of this study was to study the effects of the airflow in the non-uniform combustion core shape (NCCS) on the biochar production characteristic of the 50L-HBGS. The new design of the NCCS was constructed and studied to replace the existing combustion core shape (ECCS) at Mahasarakham University. The height, air inlet, and air outlet diameters of the NCCS were designed at 45, 24, and 11.4 cm, respectively. The NCCS with 21 holes of the pyrolysis gas outlet, a diameter of 4 mm for each, was integrated into the 50L-HBGS and performed comparative tests to the ECCS using 9 kg of bamboo wood chunks in three consecutive experiments. The airflow and the combustion behavior were studied through the stove temperature profiles, which were recorded every 5 minutes using a digital data logger. The biochar products were studied using the scanning electron microscope (SEM) with the energy dispersive x-ray spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR), and the proximate analysis technique. The study indicated that the 50L-HBGS with the NCCS made significantly improved the airflow rates in the combustion core, resulting in better continuous burning during the ignition state than with the ECCS. Moreover, the pyrolysis temperatures were significantly improved, it was provided temperatures during the pyrolysis process reached higher than 500 oC, resulting in the liquid tar being removed and no unburned wood chunks remaining at the end. The characterization result demonstrated that the 50L-HBGS with the NCCS had created biochar within a range of micropore and macrospore sizes and high fixed carbon content, which could be advantageously used for different agricultural and carbon sequestration applications.
Rosmarinic acid as a potential anti-hyperlipidemic agent
Authors: Hamza Elbouny  , Ayoub Amssayef  , Chakib Alem
Published: September 2023

Rosmarinic acid (RA) is a natural phytochemical that occurs in numerous plants, including Rosmarinus officinalis. This bioactive compound is widely reported to exert various pharmacological effects, including anti-hyperlipidemic activity. In this study, we reviewed the literature data on RA and hyperlipidemia research. In silico, in vitro, and in vivo studies were retrieved from Scholar, PubMed, ScienceDirect, Web of Science, and Scopus. The In silico studies revealed that RA possesses squalene synthase and 3-hydroxy-3-methylglutaryl–coenzyme A reductase enzymes inhibiting effect. Additionally, in vitro reports revealed that RA exerts remarkable lipid-lowering effects and also exhibits anti-adipogenic and anti-atherosclerotic activities. The lipid-lowering action was modulated by numerous mechanisms including the regulation of anti-inflammatory and antioxidant signaling pathways. Moreover, in vivo studies revealed that RA alleviates hyperlipidemia in animal models by modulating the expression of genes involved in hyperlipidemia as well as the regulation of gut microbiota and anti-inflammatory pathways. We conclude that RA is a multi-target anti-hyperlipidemic agent. Moreover, we suggest that the use of this bioactive compound as an anti-hyperlipidemic drug would be an effective pharmacological strategy that could provide promising options for the treatment and prevention of hyperlipidemia and its related disorders including atherosclerosis.
Filip Buonaccorsi Kallimach „De legitimo amore”
Authors: Głombiowska Zofia
Published: September 2023

The article is an analysis of three works by Filip Kallimach (Filippo Buonaccorsi) regarding marriage (elegy XXII, Epithalamium Fanniae ac Musaei, carmen Ad se ipsum). In the collections of Roman elegies from the Augustian era, there are no wedding pieces. The source of Callimachus’ idea is found by the author of the article in Epithalamium in Stellam et Violentillam by P. Papinius Statius and, indirectly, through the epithalamium of Statius – in the unpreserved elegies of L. Arruntius Stella, a poet of Domitian times.
Modelo matemático para prever probabilidade de quilombolas desenvolverem síndrome metabólica com fluxograma de atendimento de saúde
Authors: Torres Ruth Cristini , Nunes Marco Antônio Prado , Mota Marcelo Mendonça , Da Silva Tharciano Luiz Teixeira Braga , Oliveira Cristiane Costa da Cunha , De Melo Cláudia Moura
Published: September 2023

Desenvolveu-se um modelo matemático utilizando algoritmos de Machine learning para prever probabilidade de quilombolas desenvolverem síndrome metabólica, bem como propor um fluxograma de atendimento de saúde. Este foi um estudo transversal com uso de inteligência artificial. Adotou-se como variável dependente ter ou não síndrome metabólica. Foi realizada a análise bivariada comparando-se as variáveis independentes, os indicadores antropométricos e bioquímicos em relação a presença de síndrome metabólica e as variáveis categóricas que foram avaliadas pelo teste do Qui-quadrado (p <0,05). Utilizou-se o teste de Análise de Variância ou Kruskal-Wallis conforme a tendência de normalidade avaliada pelo teste de Shapiro-Wilk e a ferramenta de análise de dados machine learning, por meio do método de Árvore de Decisão. A árvore de decisão para predição de síndrome metabólica em quilombolas apresentou acurácia de 75%, gerando um gráfico em relação ao processo, ilustrado por meio de fluxograma para orientar a tomada de decisão em relação à saúde e prevenção de síndrome metabólica. O modelo preditivo permitiu identificar os pontos de corte específicos dos indicadores antropométricos mais importantes a serem mensurados no primeiro atendimento de saúde dos quilombolas. A acurácia do modelo preditivo permite a aplicação do fluxograma em outras comunidades quilombolas, apresentando-se como uma ferramenta tecnológica facilitadora para tomada de decisão em saúde.
The Elephant in the Room: p-hacking and Accounting Research
Authors: Gow Ian D.
Published: September 2023

Ohlson (2025. Empirical accounting seminars: Elephants in the room. Accounting, Economics, and Law: A Convivium 15, 1–8) draws on his experience in empirical accounting seminars to identify five “elephants in the room”. I interpret each of these elephants as either a variant or a symptom of p-hacking. I provide evidence of the prevalence of p-hacking in accounting research that complements the observations made by Ohlson (2025. Empirical accounting seminars: Elephants in the room. Accounting, Economics, and Law: A Convivium 15, 1–8). In this paper, I identify a number of steps that could be taken to reduce p-hacking in accounting research. I conjecture that facilitating and encouraging replication alone could have profound effects on the quality and quantity of empirical accounting research.
“In the Dark, All the Shadows Disappear”: Remodelling the Poetics of Gripping Horror in Stephen King’s The Institute
Authors: Bohovyk Oksana , Bezrukov Andrii
Published: September 2023

Transformations in the perception of horror by modern readers have provoked an increased tolerance for cruelty and death. This increase challenges authors to use special means of emotional arousal in order to appeal to contemporary audiences. One of Stephen King’s most recent books, The Institute (2019), is replete with such special means. The novel deals with unspeakable terror and centres on a group of psychic kids kidnapped and placed in brutal conditions to serve the dark purposes of powerful men. This article explores King’s ways of expressing horror by affecting universal human experiences, emotions, and feelings. It applies an interdisciplinary perspective based on psychological and hermeneutic approaches to argue that in the non-otherworldly and non-monster horror The Institute, King involves a combination of vocabulary inventions, syntactic transformations, letter emphases, and refined literary devices to create a terrifying atmosphere. These means are explicated in the article to argue that the violation of human rights and fundamental freedoms is, in many ways, more shocking and frightening than traditional bloody images. They help King remodel a dark realm of gripping horror, where fear arises primarily out of a sense of the distorted world order, and enable the writer to critique social institutions for their approval of horrendous harm.
The “Ecological Imperative” in Literary Studies
Authors: Zapf Hubert
Published: September 2023

The ‘ecological imperative’ (Hans Jonas) manifests in different ways according to the linguistic, generic, medial, and semiotic conditions in which it is communicated. This is also true of creative forms of cultural practice such as literature and the aesthetic. The ecological imperative in literature is conveyed not primarily through its discursive content but through the narrative, formal, and aesthetic procedures themselves that literary texts employ, that is, through the translation of the autopoietic complexities of the aesthetic into the co-creative responsiveness of its recipients. The paper starts with some comments on the underestimated relationship between literature and survival; looks at some of the ways in which the intrinsic eco-ethical dimension of literature has been described in ecocriticism, distinguishing three major directions of material, political, and cultural ecology in the field; and addresses the ecological imperative in transdisciplinary contexts that are significant for environmental studies in general, sustainability and the Anthropocene. The paper ends with a list of features of literature as a medium of the ecological imperative from a cultural-ecological perspective.
Inflammation-related signaling pathways in tendinopathy
Authors: Jiang Li , Liu Tianzhu , Lyu Kexin , Chen Yixuan , Lu Jingwei , Wang Xiaoqiang , Long Longhai , Li Sen
Published: September 2023

Tendon is a connective tissue that produces movement by transmitting the force produced by muscle contraction to the bones. Most tendinopathy is caused by prolonged overloading of the tendon, leading to degenerative disease of the tendon. When overloaded, the oxygen demand of tenocytes increases, and the tendon structure is special and lacks blood supply, which makes it easier to form an oxygen-deficient environment in tenocytes. The production of reactive oxygen species due to hypoxia causes elevation of inflammatory markers in the tendon, including PGE2, IL-1β, and TNF-α. In the process of tendon healing, inflammation is also a necessary stage. The inflammatory environment formed by cytokines and various immune cells play an important role in the clearance of necrotic material, the proliferation of tenocytes, and the production of collagen fibers. However, excessive inflammation can lead to tendon adhesions and hinder tendon healing. Some important and diverse biological functions of the body originate from intercellular signal transduction, among which cytokine mediation is an important way of signal transduction. In particular, NF-κB, NLRP3, p38/MAPK, and signal transducer and activator of transcription 3, four common signaling pathways in tendinopathy inflammatory response, play a crucial role in the regulation and transcription of inflammatory factors. Therefore, summarizing the specific mechanisms of inflammatory signaling pathways in tendinopathy is of great significance for an in-depth understanding of the inflammatory response process and exploring how to inhibit the harmful part of the inflammatory response and promote the beneficial part to improve the healing effect of the tendon.
Crystal structure of N-cyclopropyl-3-hydroxy-4-methoxybenzamide, C11H13NO3
Authors: Tong Hongjuan , Xu Xiaona , Zhu Zhoujing , Liu Bin
Published: September 2023

C11H13NO3, monoclinic, P21/n (no. 14), a = 8.0478(3) Å, b = 9.8093(4) Å, c = 13.1602(5) Å, β = 104.712(2)°, V = 1004.85(7) Å3, Z = 1, R

gt
(F) = 0.0395, wR

ref
(F
2) = 0.1010, T = 170 K.
Divulgadores, no influencers: comunicación de nutricionistas en redes sociales
Authors: Marauri Castillo Iñigo , Rodríguez- González María del Mar , Marín Murillo Flora
Published: September 2023

Introducción:
La alimentación genera un interés creciente entre la población, en particular entre las personas jóvenes. La pujanza de las redes sociales hace que sean una fuente de información relevante. En ellas, perfiles expertos conviven con influencers sin formación. Metodología: En este artículo se analizan las claves de la presencia en redes sociales de siete de los nutricionistas más importantes en este ámbito en lengua española a través de una técnica cualitativa basada en entrevistas en profundidad. Resultados: Se constata la relevancia de Instagram como red más importante en nutrición. Seis de los siete se niegan a ser catalogados como influencers, concepto al que atribuyen objetivos y valores con los que no se sienten identificados, y prefieren definirse como divulgadores. Los nutricionistas destacan la importancia de adecuar el mensaje a las características de cada una de las redes sociales y solo dos de los siete combinan cuestiones personales y profesionales en sus contenidos. Discusión y conclusiones: El papel divulgador de los profesionales de la nutrición en las redes sociales adquiere una especial relevancia por la calidad deficiente de la información sobre alimentación. Sin embargo, en la literatura sobre alimentación, comunicación y redes sociales, los límites entre las personas catalogadas como influencers y aquellas profesionales de la nutrición y dietética se difuminan. En este punto, resulta revelador el resultado de la investigación cualitativa realizada, ya que se constata que los nutricionistas estudiados quieren influir, pero no ser influencers. Frente a la connotación negativa que atribuyen a este concepto, defienden la coherencia y la autenticidad. Aceptan el uso de contenido patrocinado, siempre que sea claro y transparente, aunque tres de los siete aseguran haber sido testigo de casos de mala praxis.
The Effect of Lifting Straps on Deadlift Performance in Females
Authors: Trahey Kevin M. , Lapp Evan M. , Talipan Trent N. , Guydan Thomas J. , Krupka Alexander J. , Ellis Carrie E.
Published: September 2023

Trahey, KM, Lapp, EM, Talipan, TN, Guydan, TJ, Krupka, AJ, and Ellis, CE. The effect of lifting straps on deadlift performance in females. J Strength Cond Res 37(10): 1924–1928, 2023—Using lifting straps (LS) while deadlifting may increase the total number of repetitions performed and barbell velocity, and preserve grip strength; however, research in this area has only been conducted on men. This study investigated the effects of lifting straps on the total number of repetitions, mean and peak barbell velocity, and grip strength during the deadlift exercise in women. Ten women (20.1 ± 1.1 years; 165.4 ± 5.6 cm, 68.9 ± 10.3 kg) with 3.2 ± 2.1 years of resistance training experience participated in the study. After completing a 1-repetition maximum (1RM) test without LS, subjects completed 2 protocols: performing 3 sets of as many repetitions as possible of 80% 1RM with lifting straps (WS) and without lifting straps (NS). During both protocols, mean and peak barbell velocity were measured during each set, and grip strength was recorded before deadlifting and after each set. Repeated-measures analysis of variance were used to examine differences in the variables of interest, with an alpha level of 0.05 used to establish statistical significance. The WS condition allowed participants to perform significantly more reps while resulting in no statistically significant differences in mean or peak barbell velocity. The magnitude of grip strength loss was significantly lower during the WS condition. Results indicate that using LS while deadlifting allows women to perform more repetitions with greater preserved grip strength without negatively affecting barbell velocity. Thus, LS appear beneficial for deadlift performance in women and should be considered during resistance training involving the deadlift exercise.
Effect of 3 Different Set Configurations on Kinematic Variables and Internal Loads During a Power Snatch Session
Authors: Nagatani Tsuyoshi , Kendall Kristina L. , Guppy Stuart N. , Poon Wayne C.K. , Haff G. Gregory
Published: September 2023

Nagatani, T, Kendall, KL, Guppy, SN, Poon, WCK, and Haff, GG. Effect of 3 different set configurations on kinematic variables and internal loads during a power snatch session. J Strength Cond Res 37(10): 1929–1938, 2023—The aim of this study was to investigate the effect of 3 different set configurations on kinematic variables and internal loads during multiple sets performed with the power snatch. Ten strength-power athletes with at least 6 months of training experience performing the power snatch participated in this study, which consisted of 3 experimental protocols performed in a randomized repeated-measures design. The 3 protocols involved performing the power snatch for 3 sets of 5 repetitions at an average load of 75% 1 repetition maximum with a traditional (TRAD), cluster (CLU), or ascending cluster (A-CLU) protocol, where the training load was progressively increased across the set. Kinematic variables and internal loads (heart rate, blood lactate, and rate of perceived exertion) were measured during each protocol. The athletes maintained peak velocity (PV) and peak power (PP) and exhibited lower internal loads during CLU sets when compared with TRAD sets, whereas they displayed significant decreases in PV during TRAD sets. However, there were no statistically significant differences in PV and PP responses between the TRAD and CLU protocol. The athletes exhibited a significant decrease in PV, whereas PP was increased across each set in the A-CLU protocol, with lower internal loads observed compared with the TRAD protocol. Overall, the training loads used in this study do not appear to maximize the benefits of using CLU set during 3 sets of power snatches performed for 5 repetitions. In addition, A-CLU sets may potentially be useful as a means of maximizing the power output of the athlete.
Predicting Weight Category–Specific Performance Zones for Olympic, World, and European Weightlifting Competitions
Authors: Chavda Shyam , Comfort Paul , Lake Jason P. , Bishop Chris , Turner Anthony N.
Published: September 2023

Chavda, S, Comfort, P, Lake, JP, Bishop, C, and Turner, AN. Predicting weight category–specific performance zones for Olympic, World, and European weightlifting competitions. J Strength Cond Res 37(10): 2038–2045, 2023—Understanding the total likely required weight category to achieve a specific rank within a specific competition can aid in the long-term and short-term preparation and tactics for performance teams. The primary objective of this investigation was to develop a set of predictive models for new weight categories across 5 performance zones for 3 major weightlifting competitions. Performance total (Ptot) data for top 15 male athletes were obtained from the International Weightlifting Federation website from 1998 to 2020 across the Olympics, and World and European Championships. A second-order polynomial regression was conducted with 95% confidence, and predictive intervals were calculated. The average of the newly contested body mass was then used as the intercept. Predictions were compared against current performances of the new weight categories up to the 2020 Olympics. Results revealed that the models for all competition types varied in their predictive ability for each performance zone, across each new weight category. On average, predicted Ptot displayed a difference from actual Ptot of 3.65 ± 2.51% (12.46 ± 9.16 kg), 0.78 ± 3.29% (2.26 ± 10.08 kg), and −1.13 ± 3.46% (−4.32 ± 11.10 kg) for the Olympics, and World and European Championships, respectively. The results suggest that the predictive models may be a good indicator of future performances; however, the models may have greater efficacy in some weight categories and performance zones than others.
Regulatory Light-Chain Phosphorylation During Weightlifting Training: Association With Postactivation Performance Enhancement
Authors: Chiu Loren Z. F. , Fry Andrew C. , Galpin Andrew J. , Salem George J. , Cabarkapa Dimitrije
Published: September 2023

Chiu, LZF, Fry, AC, Galpin, AJ, Salem, GJ, and Cabarkapa, D. Regulatory light-chain phosphorylation during weightlifting training: association with postactivation performance enhancement. J Strength Cond Res 37(10): e563–e568, 2023—Postactivation performance enhancement has been reported for multijoint resistance exercise, with both neural and intrinsic muscle mechanisms suggested as contributing factors. The purpose of this investigation was to examine whether regulatory light-chain (RLC) phosphorylation in a primary mover is associated with enhanced weightlifting performance. Nine male athletes performed 15 sets of 3 repetitions of a multijoint weightlifting activity (clean pull) at 85% 1 repetition maximum. Measures of performance, peak barbell velocity (PV), and average barbell power (AP) were determined by video analysis. Muscle biopsies were taken within 30–60 seconds of completion of the previous lifting set from the vastus lateralis before (PRE), during (MID), and after (POST) a training session. AP was significantly greater for sets 3, 4, and 5 compared with set 1, with large effect sizes (0.8–1.0). Increases in PV did not reach significance; however, the effect size increase for sets 3 and 4 versus set 1 was moderate (0.4). Relative change scores for AP and RLC phosphorylation were positively and negatively correlated at MID (r = 0.60; p = 0.05) and POST (r = −0.74; p = 0.01) exercise, respectively. These data suggest that RLC phosphorylation initially may be associated with postactivation performance enhancement during repeated multijoint exercise.
Research on the Effect of Density on the Outgassing Characteristics of Ceramics
Authors: Luo Yan , Wang Kuibo , Wu Xiaobin
Published: September 2023

In order to systematically assess the influence of the internal structure on the outgassing property, alumina ceramics with different porosity were first prepared by four sintering processes, and then their measurements of the outgassing rate and desorption gas components were performed using the throughput method. Experimental results show that when the alumina sample is exposed to vacuum for just a few hours, surface outgassing dominants and the main outgassing component is water vapor. After sufficiently long vacuum extraction, the gas inside the alumina ceramic is gradually released. In this test, the gas released from the internal structure plays a dominant role after 48 h pumping of 600 L/s. Combined with the microstructure analysis, it is further concluded that the denser the alumina structure is, the lower the vacuum outgassing rate is and the lower the partial pressure of the individual gas components is. It can also be observed that the internal structure still has some influence on the outgassing characteristics of the material, although to a slightly lower degree than the surface properties compared to previous studies.
Nonpharmacological Interventions to Reduce Sedation and General Anesthesia in Pediatric MRI: A Meta-analysis
Authors: Thestrup Jakob , Hybschmann Jane , Madsen Thurid W. , Bork Nanna E. , Sørensen Jette L. , Afshari Arash , Borgwardt Lise , Berntsen Marianne , Born Alfred Peter , Aunsholt Lise , Larsen Vibeke A. , Gjærde Line K.
Published: September 2023

CONTEXT

Nonpharmacological strategies are increasingly used in pediatric procedures, but in pediatric MRI, sedation and general anesthesia are still commonly required.

OBJECTIVES

To evaluate the effectiveness of nonpharmacological interventions in reducing use of sedation and general anesthesia in pediatric patients undergoing MRI, and to investigate effects on scan time, image quality, and anxiety.

DATA SOURCES

We searched Ovid Medline, CINAHL, Embase, and CENTRAL from inception through October 10, 2022.

STUDY SELECTION

We included randomized controlled trials and quasi-experimental designs comparing the effect of a nonpharmacological intervention with standard care on use of sedation or general anesthesia, scan time, image quality, or child and parental anxiety among infants (<2 years), children, and adolescents (2–18 years) undergoing MRI.

DATA EXTRACTION

Standardized instruments were used to extract data and assess study quality.

RESULTS

Forty-six studies were eligible for the systematic review. Limited to studies on children and adolescents, the meta-analysis included 20 studies with 33 873 patients. Intervention versus comparator analysis showed that nonpharmacological interventions were associated with reduced need for sedation and general anesthesia in the randomized control trials (risk ratio, 0.68; 95% confidence interval, 0.48–0.95; l2 = 35%) and nonrandomized studies (risk ratio, 0.58; 95% confidence interval, 0.51–0.66; l2 = 91%). The effect was largest among children aged 3 to 10 years when compared with older children and adolescents aged 11 to 18 years.

LIMITATIONS

There was substantial heterogeneity among nonrandomized studies.

CONCLUSIONS

Nonpharmacological interventions must be considered as standard procedure in infants, children, and adolescents undergoing MRI.
Formas de enfrentamento do câncer de mama: discurso de mulheres mastectomizadas
Authors: Brito Paloma Karen Holanda , Carneiro Açucena de Farias , Da Silva Raquel de Jesus Rocha , Barbalho Isabela Lunara Alves , De Lima Mariana Alexandre Gadelha , Fernandes Marcelo Costa
Published: September 2023

Introdução: Na neoplasia de mama ocorrem inúmeras transformações na vida da pessoa acometida e de todas as pessoas próximas, sentimentos como medo, angústia e tristeza. Diante disso, a identificação dos métodos usados para enfrentar a neoplasia de mama faz-se crucial, visto que proporciona melhor vivência desse momento por parte da mulher e de todos os envolvidos.
Objetivo: Compreender as formas de enfrentamento do câncer de mama por meio do discurso de participantes de um grupo de apoio.
Metodologia: Pesquisa descritiva com abordagem qualitativa realizada com 10 mulheres que participam de um grupo geral de apoio, localizado em um município da Paraíba. Para a coleta de dados, utilizou-se entrevista semiestruturada, e como processo metodológico para a análise dos dados, o Discurso do Sujeito Coletivo. 
Resultados: Foi possível a compreensão de três ideias centrais em relação às formas de enfrentamento do câncer de mama: “Ancoragem na fé e espiritualidade”; “Suporte familiar”; e “Grupo de apoio”.
Conclusão: O estudo atingiu seu objetivo de identificar as principais formas de enfrentamento do câncer de mama por mulheres mastectomizadas, podendo elucidar a importância da fé e espiritualidade, o suporte familiar e a participação em grupos de apoio por meio do discurso das participantes.
Treatment of obesity. A review of selected guidelines
Authors:   Wrocław Regional Specialist Hospital in Wrocław Research and Development Center, Wrocław, Poland, Dereziński Marcin Maciej , Przeorski Krzysztof ,   Jan Mikulicz-Radecki Medical University Hospital, Wrocław, Poland, Lisiak Nicola ,   Jan Mikulicz-Radecki Medical University Hospital, Wrocław, Poland, Dal Canton Zofia ,   Jan Mikulicz-Radecki Medical University Hospital, Wrocław, Poland
Published: September 2023

Treatment of obesity is one of the challenges of the 21st century. It is a risk factor for the development of other diseases such as hypertension, coronary heart disease and cancer. The diagnosis of obesity should be based on body mass measurements, taking into account height and sex. It is also recommended to measure waist and hip circumference. Lifestyle modifications, which include increased physical activity and reduced calorie intake, are the primary method of treating obesity. Unfortunately, changing habits is difficult and even unattainable for many patients. Due to the increasing prevalence of obesity in the society, this review of guidelines is addressed to general practitioners and all physicians who encounter obese patients in their practice. Each of the guidelines analysed emphasises prevention, early diagnosis, and treatment of obesity. Behavioural and dietary changes are central in obesity management. The guidelines also point to the role of effective doctor–patient communication, as well as the need for a multidisciplinary management of obesity by a team composed of a physician, dietitian, and often physiotherapist. Pharmacotherapy, which was introduced in recent years as a supportive treatment, is another pillar of obesity therapy. Therefore, we also reviewed guidelines regarding pharmacological treatment of obesity. We focused on summarising indications for anti-obesity medications, descriptions of individual medications, their dosing regimens, as well as therapeutic goals, pointing out differences between individual recommendations.
Contemporary Trends in the Author’s Ceramics by V. V. Portnova
Authors:   The Sverdlovsk regional museumof the local history named after O. E. Kler, Pistsova Irina N.
Published: September 2023

The article is devoted to the development of the Ural artistic ceramics in the late XX — early XXI century, in the history of which a significant role belongs to the representatives of the Krasnoyarsk ceramic school. During this period, changes in socio­economic conditions led to shift in cultural priorities, which manifested themselves in the polystylistics of postmodernism, that influenced the decorative and applied arts of Russia. The research of the issue is based on the art history and interdisciplinary scientific methods. Using the example of the work of the famous ceramist V. V. Portnova, the author examines the current trends in the shaping of contemporary Russian ceramics­ that are interest in tectonics and work with the surface. The author analyzes the evolution of the creative style of the ceramist, revealing individual engagement in the artistic and figurative solution of ceramic objects.