bluuebunny/crossref_metadata_2025 huggingface dataset:
Actuation performance of a photo-bending crystal modeled by machine learning-based regression
Authors: Ishizaki Kazuki , Sugimoto Ryota , Hagiwara Yuki , Koshima Hideko , Taniguchi Takuya , Asahi Toru
Published: March 2021

The bending deflection and blocking force of photo-bending crystals of different sizes were experimentally measured at various light intensities, and then modeled by the machine learning-based regression.
Biaxial strain, electric field and interlayer distance-tailored electronic structure and magnetic properties of two-dimensional g-C3N4/Li-adsorbed Cr2Ge2Te6 van der Waals heterostructures
Authors: Gao Yaoqi , Zhou Baozeng , Wang Xiaocha
Published: March 2021

It is found that the biaxial strain, electric field and interlayer distance can effectively modulate the electronic structure and magnetic properties of two-dimensional van der Waals heterostructures.
Dynamics of coordination of H3O+ and NH4+ in crown ether cavities
Authors: Bessam S. , Reguig F. Hamza , Krallafa A. M. , Martínez-Haya B.
Published: March 2021

H3O+ and NH4+ cations display active intracavity H-bonding dynamics in crown ether complexes.
The outer membrane protein Amuc_1100 of Akkermansia muciniphila promotes intestinal 5-HT biosynthesis and extracellular availability through TLR2 signalling
Authors: Wang Junchao , Xu Wenjuan , Wang Rongjuan , Cheng Rongrong , Tang Zhengquan , Zhang Min
Published: March 2021

The outer membrane protein Amuc_1100 of A. muciniphila promotes intestinal 5-HT biosynthesis and extracellular availability through TLR2 signalling. Conversely, 5-HT will in turn to affect the composition of microorganisms in the gut.
MEMS-compatible, gold nanoisland anchored 1D aligned ZnO heterojunction nanofibers: unveiling the NO2 sensing mechanism with operando photoluminescence studies
Authors: Vishnuraj Ramakrishnan , Dhakshinamoorthy Jayaseelan , Nair Keerthi G. , Aleem Mahaboobbatcha , Pullithadathil Biji
Published: March 2021

Single step, on-chip fabrication of 1D aligned Au functionalized heterojunction ZnO nanofibers via coaxial electrospinning with in situ photoreduction has been demonstrated.
Ba2TiMnO6 two-dimensional nanosheets for rhodamine B organic contaminant degradation using ultrasonic vibrations
Authors: Sharma Aditi , Bhardwaj Upasana , Kushwaha H. S.
Published: March 2021

Piezocatalyst Ba2TiMnO6 nanosheets (BTMO NS) for waste water treatment.
The bimetallic and the anchoring group effects on both optical and charge transport properties of hexaphyrin amethyrin
Authors: Borges-Martínez Merlys , Montenegro-Pohlhammer Nicolás , Cárdenas-Jirón Gloria
Published: March 2021

Bimetallic Cu(ii)-hexaphyrin amethyrin proposed as a molecular switch operated by the application of an external magnetic field.
Preparation and application of solvent-free liquid proteins with enhanced thermal and anhydrous stabilities
Authors: Brogan Alex P. S.
Published: March 2021

This perspective details a robust chemical modification strategy to protect proteins from temperature, aggregation, and non-aqueous environments.
Pyridine-pyrazole based Al(iii) ‘turn on’ sensor for MCF7 cancer cell imaging and detection of picric acid
Authors: Saha Sayan , De Avik , Ghosh Arijit , Ghosh Avik , Bera Kaushik , Das Krishna Sundar , Akhtar Sohel , Maiti Nakul C. , Das Abhijit Kumar , Das Benu Brata , Mondal Raju
Published: March 2021

We report herein the development of a new pyridine-pyrazole based bis-bidentate asymmetric chemosensor that shows excellent turn-on chelation-enhanced Al3+-responsive fluorescence.
Metamaterial-like aerogels for broadband vibration mitigation
Authors: Malakooti Sadeq , Hatamleh Mohammad I. , Zhang Rui , Taghvaee Tahereh , Miller Max , Ren Yao , Xiang Ning , Qian Dong , Sotiriou-Leventis Chariklia , Leventis Nicholas , Lu Hongbing
Published: March 2021

We present metamaterial-like aerogels that provide broadband low-frequency vibration mitigation through their self-assembled locally resonant microstructures. Simulations confirm the presence of a negative dynamic stiffness for the aerogels.
Adhesion as a trigger of droplet polarization in flowing emulsions
Authors: Golovkova Iaroslava , Montel Lorraine , Pan Franck , Wandersman Elie , Prevost Alexis M. , Bertrand Thibault , Pontani Lea-Laetitia
Published: March 2021

When adhesive emulsions are flowed in 2D constrictions, their local rearrangements are impaired, leading to higher deformations. The adhesive emulsions are globally more aligned in the direction of elongation, leading to a global polarization.
In memoriam Vittorio Degiorgio (5 January 1939–17 January 2021)
Authors: Piazza Roberto
Published: March 2021

Celebrating the life of Vittorio Degiorgio.
Identification of PSMD7 as a prognostic factor correlated with immune infiltration in head and neck squamous cell carcinoma
Authors: Zhang Si , Yu Siwei , Wang Jiulong , Cheng Zhigang
Published: March 2021

Background: Recurrent locally advanced or metastatic head and neck squamous cell carcinoma (HNSCC) is associated with dismal prognosis because of its highly invasive behavior and resistance to conventional intensive chemotherapy. The identification of effective markers for early diagnosis and prognosis is important for reducing mortality and ensuring that therapy for HNSCC is effective. Proteasome 26S subunit, non-ATPase 7 (PSMD7) is an ATP-independent component of the 19S regulatory subunit. The prognostic value of PSMD7 and the association with immune infiltration in HNSCC remains unclear.

Methods: The Sangerbox, Oncomine, UALCAN and Human Protein Atlas (HPA) databases were used to examine PSMD7 expression profiles in HNSCC. The CVCDAP was used to analysis the association of PSMD7 with the prognosis of patients with HNSCC. The mechanism was investigated with gene set enrichment analysis (GSEA). The association between expression of PSMD7 and immune infiltration in HNSCC was investigated using the Tumor Immune Estimation Resource (TIMER), TISIDB database and CIBERSORT algorithm.

Results: PSMD7 expression was significantly up-regulated in HNSCC compared with relative normal tissues. In addition, up-regulated PSMD7 expression was associated with various clinicopathological parameters. High expression of PSMD7 suggested inferior survival of HNSCC patients. GSEA and CERES score indicated that PSMD7 was closely correlated with tumor-related signaling pathways and cell survival. Functional analyses revealed that PSMD7 was positively correlated with various infiltration levels. Moreover, PSMD7 influenced the prognosis of HNSCC patients partially via immune infiltration.

Conclusion: Our findings suggest that PSMD7 is associated poor prognosis in patients with HNSCC and plays an important role in tumor-related immune infiltration.
Mechanisms and clinical manifestations of cardiovascular toxicities associated with immune checkpoint inhibitors
Authors: Baik Alan H. , Tsai Katy K. , Oh David Y. , Aras Mandar A.
Published: March 2021

Immunotherapies have greatly expanded the armamentarium of cancer-directed therapies in the past decade, allowing the immune system to recognize and fight cancer. Immune checkpoint inhibitors (ICIs), in particular, have revolutionized cancer treatment and have demonstrated survival benefit in numerous types of cancer. These monoclonal antibodies increase anti-cancer immunity by blocking down-regulators of adaptive immunity, including cytotoxic T lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 (PD-1), and its ligand (PD-L1), resulting in anti-tumor activity. As ICIs increase immune system activation, they can cause a wide range of inflammatory side effects, termed immune-released adverse events. Though these toxicities can affect nearly any organ, the most fatal toxicity is myocarditis. Here, we discuss the diverse spectrum of cardiovascular toxicities associated with ICI use. In addition, we provide insight and future directions on mechanisms and treatments for immune-related adverse events (irAEs) involving the myocardium, pericardium, vasculature, and conduction system.
Vehicle detection based on improved multitask cascaded convolutional neural network and mixed image enhancement
Authors: Xu Ke , Gong Hua , Liu Fang
Published: March 2021

In order to increase the detection effect of fuzzy vehicles and small size vehicles, an improved multitask cascaded convolutional neural network (IMC‐CNN) based on mixed image enhancement is proposed. Firstly, contrast limited adaptive histogram equalisation and multi‐scale Retinex are used to enhance images. Mixed image enhancement can effectively solve the problems of image blurring, low contrast and uneven illumination when the imaging environment is not ideal. IMC‐CNN includes two stages: object location and object classification. The object location network based on multi‐layer feature fusion can locate and extract the object from complex background, and output regions contain only a single vehicle object. The object classification network is a lightweight convolutional neural network with only two convolutional layers, which can effectively reduce information loss and improve the classification accuracy of small objects and fuzzy objects. In addition, online hard example mining algorithm and focal loss function are adopted in network training. These strategies can solve the problem of unbalance between positive and negative samples. To verify the validity of the proposed algorithm, the experiments are performed on SYIT‐Fuzzy dataset and COCO‐Vehicle dataset. Compared with Faster R‐CNN, YOLO v4 and other recent models, the average classification accuracy of the proposed method is significantly increased.
Symmetrical double‐loop H‐field probe with floating shield for improving sensitivity and electric field suppression
Authors: Liu Jiesheng , Xiao Meizhen , He Xiao , Fang Wenxiao , Shao Weiheng , Huang Quan , Lu Guoguang , Wang Lei , Huang Yun , En Yunfei , Yao Ruohe
Published: March 2021

A magnetic near‐field probe (H‐field probe) with dual output has been developed using a four‐layer printed circuit board (PCB) technique. To achieve the improvement of detection sensitivity, the symmetrical double‐loop is adopted to double the detection signal while suppressing the electric field coupling, which is also illustrated in a circuit model. The calibration factor (defined as the ratio of the external magnetic field to the induced response voltage of the probe) of the proposed H‐field probe reaches 37.74 [dB (A/m)/V] at 0.5 GHz with the loop area of 0.8 mm2, resulting in a better sensitivity than the single‐loop probe. For the suppression of unwanted electric field a floating shield is added to the bottom of the probe, leading to an excellent common electric field suppression ratio of 29 dB in the frequency range up to 10 GHz. The probe is also characterised by parameters such as high differential electric field suppression, spatial resolution and probe influence on the device under test.
The aftermath of nova Centauri 2013 (V1369 Centauri)
Authors: Mason Elena , Shore Steven N. , Drake Jeremy , Howell Steve B. , Kuin Paul , Magaudda Enza
Published: March 2021

Context.Classical nova progenitors are cataclysmic variables and very old novae are observed to match systems with high mass transfer rates and (relatively) long orbital periods. However, the aftermath of a classical nova has never been studied in detail.

Aims.We intend to probe the aftermath of a classical nova explosion in cataclysmic variables and observe as the binary system relaxes to quiescence.

Methods.We used multiwavelength time-resolved optical and near-infrared spectroscopy for a bright, well-studied classical nova five years after outburst. We were able to disentangle the contribution of the ejecta at this late epoch using its previous characterization, separating the ejecta emission from that of the binary system.

Results.We determined the binary orbital period (P = 3.76 h), the system separation, and the mass ratio (q ≳ 0.17 for an assumed white dwarf mass of 1.2M⊙). We find evidence of an irradiated secondary star and no unambiguous signature of an accretion disk, although we identify a second emission line source tied to the white dwarf with an impact point. The data are consistent with a bloated white dwarf envelope and the presence of unsettled gas within the white dwarf Roche lobe.

Conclusions.At more than 5 years after eruption, it appears that this classical nova has not yet relaxed.
Focal-plane-assisted pyramid wavefront sensor: Enabling frame-by-frame optical gain tracking
Authors: Chambouleyron V. , Fauvarque O. , Sauvage J.-F. , Neichel B. , Fusco T.
Published: March 2021

Aims. With its high sensitivity, the pyramid wavefront sensor (PyWFS) is becoming an advantageous sensor for astronomical adaptive optics (AO) systems. However, this sensor exhibits significant non-linear behaviours leading to challenging AO control issues.

Methods. In order to mitigate these effects, we propose to use in addition to the classical pyramid sensor a focal plane image combined with a convolutive description of the sensor to fast track the PyWFS non-linearities, the so-called optical gains (OG).

Results. We show that this additional focal plane imaging path only requires a small fraction of the total flux while representing a robust solution to estimating the PyWFS OG. Finally, we demonstrate the gain that our method brings with specific examples of bootstrapping and handling non-common path aberrations.
Improving the quality of training drama therapy students through the metaphors of experiencing fear
Authors: Polínek Martin Dominik , Vachkov Igor
Published: March 2021

The present study is aimed at introducing effective psychological instruments the authors have been using in a therapeutic interaction with people (children, adolescents, and youth) with different problems for a long time in the educational process. The main focus of the study is the metaphors and motivation of fear and anxiety the use of which in the process of providing psychological assistance to students can improve the quality of the educational process and educational influences on them since these tools allow students and teachers to safely (due to the metaphorical distance) address sensitive topics that often present the source of anxiety and fear in students while neglecting these topics often hinders the creation of a safe learning environment. Metaphors are actively used in a variety of psychotherapeutic approaches although very little attention is paid to their implementation in the educational environment. The goal of the present study is to disclose the opportunities of using metaphors of experiencing fear in working with university students. The proposed hypothesis states that the implementation of metaphors of experiencing fear in work with university students will contribute to the improvement of their self-assessment of subjective well-being. The study presents the analysis of the results of focus group studies conducted during experiments with the students of the “Drama Therapy” specialty at the Palacký University of Olomouc in the Czech Republic. With the use of the grounded theory method, it is demonstrated that work with metaphors of experiencing fear leads to becoming aware of self-support mechanisms, processing suppressed emotions, relaxation, inner liberation, and the activation of personal resources. These results open up prospects for the active use of metaphorization of various (including negative) experiences in providing psychological assistance to students.
Study of the parental assessment of the adaptation of first-graders with health limitations to the educational organization, considering the features of the urban environment
Authors: Zhuravleva Zhanna , Pavlova Anna , Mironova Angelina , Hamanovich Viktoryia
Published: March 2021

Admission of a child to an educational organization is a difficult period for him. What should be considered when creating an educational environment at school and home? What determines successful adaptation of first-graders to new academic activities, which require from child certain knowledge about the world, good visual-motor coordination, possession of mental operations, planning skills and self-regulation of behavior, verbal communication, and the manifestation of volitional efforts to fulfill educational tasks? The successful adaptation of a child largely influences his further socialization. Modernization of education, aimed at ensuring its accessibility, individualization, and differentiation, creating conditions for achieving new contemporary quality of primary level of general education, leads to heterogeneity in the composition of pupils in terms of their psychophysical development. This complicates the adaptation of both first-graders with health limitations (HL) and children with regular development. Attracting intellectual and socio-cultural resources of the city in education, socialization, and adaptation of children with HL to new social conditions are becoming an urgent issue. The purpose of the research is to study the parental assessment of adaptation of a first-grader with HL to the educational organization in the urban environment. The authors of the article compiled a questionnaire for parents to determine the features of adaptation to the school life conditions of their children. The article presents the analysis results of the conducted survey. Research methods include quantitative assessment and qualitative analysis of the survey, as well as content analysis of relevant literature sources. The present research is caused by the insufficient theoretical study and practical development of issues related to the adaptation of first-graders with HL by parents.
Improving the quality of education at the municipal level to prepare for a new technological order
Authors: Merzlyakova Dina , Miroshnichenko Aleksey , Baranova Zubarzyat , Skryabina Darya , Samigullina Guzaliya
Published: March 2021

Preconditions of this work are stipulated by necessity to provide interrelations of forecasted targets of education and targets of development of state and society. Research is aimed at revealing features of target setting of participants in the relations in the sphere of education during preparation for new technological order. Analysis of publications devoted to the considered problem was conducted. The participants in the relations in the sphere of education were surveyed. The main results are the essence and definition of concepts of education targets and their specificity during preparation for new technological order by the participants in the relations in the sphere of education. It has been determined that all participants in the relations in the sphere of education more distinctly understand the education target in comparison with comprehension of necessity to arrange teaching in accordance with the NTI program. Herewith, the most concerned in development of education of students in NTI technologies are pedagogical staff of comprehensive educational establishments, university administration, and governmental authorities of Udmurtia. All participants in the relations in the sphere of education have higher orientation at knowledge acquisition by students in comparison with orientation at formation of personal properties (except for parents and local authorities). Consistency of targets of all participants will allow to more efficiently train students for new technological order.
Education quality from the viewpoint of educational process participants and the parties concerned
Authors: Nadtochiy Yuliya , Rozanova Yelizaveta , Solovyev Andrey , Shiryayeva Svetlana , Kazantseva Natalya
Published: March 2021

The relevance of the study of issues related to improving the quality of education in current realities is not in doubt. One may note a wide range of opinions regarding the content and essence of this concept, its structure, ensuring the quality of the educational process, in particular, in educational institutions of higher education, and understanding of the quality of existing education by the educational process participants (teachers and students) as well as parties concerned (employers, parents, etc.). Improving the quality of education is a multifaceted and continuous process that requires careful attention from the scientific community. The authors consider the main definitions of the concept of quality of education and uncover its content. To study different views on the quality of contemporary education, several surveys of the main participants in the educational process, i.e. teachers and students, were conducted. The authors revealed the opinions of employers and graduates regarding the quality of domestic higher education and, based on these qualities, created a profile of contemporary graduates (young professionals) who have received a high-quality education. As a result of the conducted research, the conclusion is confirmed that quality is understood by each person according to their accumulated experience and the subjective idea of this category, and changes according to the requirements that are dictated by society and the state in a particular historical period, as well as depending on the conditions of the surrounding reality (a clear example is a current situation with coronavirus which shows that the main skills for employees are the skills and abilities to perform work remotely, which also become key ones when making a decision by the employer about hiring an employee).
Early correctional and pedagogical assistance to children with autism as a means of improving their quality of life
Authors: Timofeeva Elena , Timofeeva Ksenia , Shinkarenko Vladimir
Published: March 2021

The present article deals with the organization and implementation of correctional care for younger children with autism spectrum disorders. The authors reveal key aspects of the problems underlying the speech and nonspeech difficulties of this category of children, as well as consider the topic of the only generally accepted method (applied behavior analysis) that is widely used when working with these children, and prove the expediency of a different approach to the complex correction of speech problems in children with communication disorders. The approach is based on the identified peculiarities of the speech and nonspeech problems of children with autism. The authors justify the choice of contemporary foreign methods (Tomatis, Floortime, and Sensory Integration) in the correction of speech and behavior of children with communication disorders based on the results of the conducted ascertaining experiment. Based on a comparative analysis of the results of ascertaining and forming experiments in the control and experimental groups, it has been proved experimentally that establishing an emotional and communicative component of the mental development of the child, as well as improving the processing of auditory, tactile, vestibular, and proprioceptive sensation speed up the corrective process that plays a crucial role in speech development and the development of nonlanguage functions. The significance of this study concerns the evidence-based use of a comprehensive approach to the correction of children with autism in the sensitive period of their development (from two to four years). Early comprehensive care provides a chance to achieve success in the social and speech development of these children by the beginning of school education (from seven to eight years), which will significantly improve the quality of their lives and contribute to the best integration into society.
Learning opportunities of urban space semiotics
Authors: Silchenkova Lyudmila , Likhachev Sergey , Desyaeva Natalya , Likhacheva Tatyana , Sheveleva Natalia
Published: March 2021

The article deals with the study of the semiotic opportunities of the urban space as a learning tool. The authors analyze the literature on urban research and point to the significant interest of the education system in various manifestations of urban life: architectural, design, environmental, adaptational, etc. The notion of “city” in numerous studies usually means an environment full of different natural objects and structures. The latter should include houses, sculptural and architectural monuments, specially organized urban space, for example, the city center and its peripheral area marked with certain signs. Researchers insist that a city is a complex semiotic space in which a citizen lives and navigates. Various types of signs are actively involved in the organization of urban life (Ch. Peirce). Thus, iconic signs make it easy to navigate the city without resorting to decoding symbolic signs, i.e. without reading the signs and names of, for example, stores: a boot hanging next to the signboard allows one to determine that the citizen is in front of a shoe store. A child navigates such signs easily, however, participating in orienting activities on par with adults. The purpose of this article is to consider the city learning opportunities for helping young children to form the semiotic activity which is included in various types of educational activities. The novelty of the research presented in the article is confirmed by the lack of scientific publications that directly consider the educational opportunities of urban space semiotics. The main research method is the code reconstruction method. The figure of a child plays an important role in the study. The child acts as the central subject of perception of the city-textbook. Following the idea of the most prominent researchers of semiotics, the authors regard the city as a text for a child to read. The analytical part of the article is based on recording children’s impressions of the urban text.
Development of youth initiative upon studying socio-cultural space of a metropolis
Authors: Sorokovykh Galina , Bannikova Lyubov , Pribylova Natalia , Staritsyna Svetlana , Vishnevskaya Yekaterina
Published: March 2021

Due to wide-scale introduction of distance learning, the education sphere faces new social and psychological problems related with self-actualization, improvement of intelligence level, and spiritual development of youth and students. Today, the young teacher is a bearer of a unique subculture, the holder of a special personal position, which is characterized by the active nature of consciousness, understanding of the importance of personal initiative in the education of the generation. We consider the student as a representative of young people, who is a carrier of cognitive activity, owning ways of interacting with social reality, including personal initiative. The status of a student of a pedagogical university in Moscow plays an important role in creating a certain socio-cultural environment of the metropolis. Research objective is to substantiate and diversify interdepartmental experience of the Institute of Foreign Languages in development of initiative and activity of students during studying socio-cultural space of the capital. This article presents the training experience of future teachers, which can be used in university educational environment, as well as illustrative examples confirming appropriateness and consistency of educational policy of Institute of Foreign Languages, Moscow City University, in this direction. The research is based on generalization of teaching experience in training teachers of the English language and theoretical methodological provisions described by leading Russian and foreign researchers. This research generalizes the most efficient methods and skills of development of youth initiative upon designing and implementation of authors’ projects of study of socio-cultural space of Moscow, the toolkit for support of students’ projects is presented. The importance of development of youth initiative for formation of socio-cultural competence of teacher and his self-education has been proven.
Training of pedagogical personnel for inclusive education children with disabilities
Authors: Yakovleva Irina , Yakovlev Sergey , Khitryuk Vera
Published: March 2021

With the spread of inclusive education, new requirements are imposed on a teacher, including their readiness to teach, educate, and help with the development of children with special educational needs. Scholars recognize the need to amend the training of general education teachers (primary school teachers and subject teachers) to form their readiness to teach school children with disabilities. The study presents an analysis of modern Russian research on this issue using methods of analysis, systematization, and comparison of modern approaches to teacher training for inclusive education of children with disabilities. The study reveals Russian scholars’ understanding of the term “readiness for inclusive education of children with disabilities” and a list of professional and personal qualities, value-semantic guidelines, and professional competencies that an inclusive education teacher should have. Scientific approaches to the training of such a specialist (competency-based, integrated) and proposed forms of education are critically analyzed, and issues of content and new technologies used in preparing a teacher for this type of professional activity (contextual, project-based learning) are considered. The study reveals the shortcomings of the modern situation in the preparation of a general school teacher for inclusive teaching of children with disabilities, and the authors’ view on changing the form of such training is proposed. As a result of the analysis, prospects for further research in the field of teacher training for inclusive education of children with disabilities are highlighted.
Mental hygiene of interpersonal relations of student-managers in a megapolis
Authors: Dedov Nikolay , Komissarova Olga , Kokhova Irina , Petrunya Oleg , Gerasimenko Tatyana
Published: March 2021

The article presents a psychological analysis of the behavior features and interpersonal relations of students-managers in a metropolis. The relevance of the present work is determined by the fact that for young people, higher education is associated with a change in their social status when they move from direct dependence on their parents to independent actions and active life in a big city. The specifics of the urban space of a metropolis have a strong influence on their mental state and understanding of the world around them. The popularity of the manager’s profession among young people entering universities has also contributed to the relevance of the study. Young people set themselves the goal of “learning to manage and lead.” The conditions of the big city impose special requirements on future managers, focusing them on the implementation of adaptive psychological functions. The manager’s ability to conform to social attitudes, to create a pleasant impression for others becomes for him a professionally important quality. As a result, students face a paradoxical situation involving a system of “double standards”. In this regard, they encounter difficulties in social adaptation and the formation of stable interpersonal relationships. To solve this problem, an empirical study was conducted, which allowed determining the values of the main strategies of interpersonal relations based on a comparative analysis of the basic ideas of first-year students. Empirical data were obtained based on the psychological method by L.N. Sobchik “Diagnostics of interpersonal relations” (DIR). The results obtained make it possible to carry out preventive psychohygienic activities with students to form their social adaptability and maintain mental health.
Integrative space of a pedagogical university as a qualitative resource for successful self-actualization of future teachers in a city context
Authors: Makhinin Aleksandr , Kozlova Tamara , Nesterova Irina , Shamanina Liliya
Published: March 2021

In the context of the unstable development of contemporary civilization, attempts to consolidate efforts among the pedagogical community to ensure the proper quality of education in the 21st century are becoming more and more relevant. It seems that the solution to such an urgent problem is feasible by developing an additive integrated model of pedagogical management based on the implementation of the integrative educational space of a pedagogical university (hereinafter – IESPU). According to the authors, the emergence and constant reproduction of relationships between the administration and employees of educational organizations of higher education to achieve the strategic goals of the university should become the main goal of developing such a pedagogical university management model. The methodological basis for the development and implementation of an additively integrated model of pedagogical management is the integrative and spatial approaches that determine the feasibility of designing IESPU and allowing providing access to the formation of teachers’ subjectivity in their own professional activities in the context of continuous personal and professional self-development. The authors consider it appropriate to offer a certain set of areas, essential in their opinion, for planning and developing an additive model of pedagogical management in the context of designing and implementing IESPU, taking into account its qualitative, spatial-temporal, socially-determined, and scientifically-grounded parameters, as well as the urban environment in which pedagogical universities are located.
Digital development trajectory as a tool for improving the quality of education
Authors: Kupriyanov Roman , Semenov Alexei , Kondratiev Vladimir , Nikulina Polina
Published: March 2021

The present article proposes an approach to using students’ digital development trajectories to improve the quality of education. Designing a digital development trajectory has a positive effect on students’ motivation and active participation in deciding on its formation. The goal of the study is to create a conception of using methods and approaches of educational data mining and machine learning in analyzing and predicting digital development trajectories to improve the educational process quality. Implementation of learning management systems with the opportunity to dynamically track students’ academic performance allows timely correcting gaps appearing in students’ knowledge and thereby reducing the risk of them falling behind in their study group. Recording the obtained results of completed assignments and interactions with learning management systems also benefits teachers who get an opportunity to receive feedback in an implicit form and account for gaps appearing in the curriculum in a processed and aggregated form. The analysis is conducted based on a database of additional education in a primary school (grades 1-3). The present study examines several scenarios of using a digital development trajectory in education including students’ progress in an academic performance trajectory based on their grades, a trajectory in terms of time spent on solving problems to determine their complexity, and a heatmap for determining problematic areas and weak spots in each teacher’s educational course. Based on educational data from a learning management system, the authors present a set of recommendations for teachers on the adaptation of their educational course to students’ abilities promoting the increase of the overall quality of education.
Training of special teachers to use the resources of Moscow E-School
Authors: Afanasyeva Yulia A. , Gravitskaya Elena G. , Paramonova Galina V. , Gromova Olga I. , Bulekbayeva Sholpan A.
Published: March 2021

This article discusses the issues of training special teachers for using modern digital educational technologies, in particular innovation resources of Moscow E-School (MES). The aim of this work is in development of technology of specialists’ training, capable to work with the resources of MES, in the frames of higher education. The following research methods were applied: surveying students, expert appraisal of students by teachers, aiming at formed skills and habits to work in MES environment. The obtained experimental results evidence that in the frames of higher education, the proposed technology of specialists’ training, capable to work with the resources of MES in the frames of optional courses, demonstrated sufficiently high results. The study revealed high satisfaction of teachers with the level of students’ qualification, namely: creative potential was enhanced, during the practice the students demonstrated higher involvement. Thus, in 2020, the teachers supervising the practice marked high level of skills of operation with MES resources demonstrated by 57% of students, which was nearly by two times higher than in 2018 (31%). In 2020, the average level was recorded for 28% of students, the low level – for 15% of students, which was nearly by two times lower than in 2018 (27%). Introduction of such optional course is exclusive, since it is oriented at training students specializing in special (defectology) education and solves the following tasks: firstly, to arm with the skills and habits of operation in digital environment, namely, MES, and secondly, to arm with specific knowledge and skills of development of electronic content for disabled children.
Education in the city of Ufa: digital environment as a condition for improving the quality of ethnocultural training of teachers
Authors: Akchulpanova Alfiya , Boronilova Irina , Syrtlanova Nelli , Shabayeva Guzel , Pilipenko Yelena
Published: March 2021

This article discusses search of adequate tools for training of psychological and pedagogical staff of preschool education institutions, aiming at improvement of living quality in city, under conditions of electronic education for working in ethnocultural environment of preschool children. The choice of humanitarian approach assuming studying of personality as a subject of cultural self-development in education is theoretically substantiated. The contents of projects on training professional staff of the City of Ufa (Bashkiria) for preschool education institutions, as well as their advanced training in the frames of implementation of innovation technologies and practices have been determined. Some activities on training of teachers for working in ethnocultural kindergartens have been described. Experience of development of online courses aimed at formation of working activities related with ICT competences of participants in educational relations has been disclosed. The following projects have been presented: Network Electronic Kindergarten promoting efficient training of teachers for working in ethnocultural educational and digital environment of Bashkiria; Centers of competence development: Preschool Education Teacher, Electronic Education Teacher, as well as workshops of department of higher education entity on World Skills of Preschool Education competence disclosing opportunities to improve life quality in city.
Analysis of electronic educational resources for distance learning
Authors: Katkova Olga , Mukhina Mariia , Chaykina Zhanna , Smirnova Zhanna , Tsapina Tatyana
Published: March 2021

This article analyzes modern trends of educational processes stipulated by features of modern society development. Modifications in surrounding reality dictate necessity of updating the learning process towards active transition to distance education. Increased demand of students for electronic educational resources stipulated necessity to analyze representation of electronic platforms and identification of their features. This work is aimed at analysis of the electronic educational resources being most popular among students, and identification of features of their use in distance education. The study was performed using analysis of scientific publications devoted to the research subject, survey and results of its analysis, analysis of electronic educational resources aiming at identification of their features for distance education. This work is comprised of two stages. At the first stage, the students of two learning levels were surveyed (universal bachelor degree course and high school), which allowed to reveal common requirements for the two levels of preparation for electronic educational resources and features of their selection by respondents. At the second stage, the most demanded for distance learning electronic educational platforms and their resources were analyzed to assist teacher to develop algorithm of combination of various electronic resources in the frames of content of certain course. A teacher should be aware of the content of the most popular educational platforms of opensource information educational environment, determine reasonability of access to this or that electronic resource and promote students to active participation in distance form.
Komplexe Posttraumatische Belastungsstörung und arbeitsbezogene Verhaltens- und Erlebensmuster
Authors: Brenner Lorena , Härtter Charlotte , Bachem Rahel , Knaevelsrud Christine , Köllner Volker
Published: March 2021

Ziel Es ist davon auszugehen, dass eine komplexe Posttraumatische Belastungsstörung (kPTBS) nach ICD-11 die Betroffenen auch im beruflichen Bereich beeinträchtigt. Die vorliegende Arbeit untersucht daher, ob zwischen Patienten mit positivem Screening auf eine kPTBS, Patienten mit positivem Screening auf eine PTBS und Patienten mit negativem Screening auf Traumafolgestörungen Unterschiede bezüglich ihrer arbeitsbezogenen Verhaltens- und Erlebensmuster (AVEM) bestehen.

Methodik Teilnehmer waren 566 Patienten einer psychosomatischen Rehabilitationsklinik (Alter M=50,96, SD 8,73 Jahre; 70,3% weiblich). Die Teilnehmer bearbeiteten zu Beginn ihres stationären Aufenthalts Selbstbeurteilungs-/ Screeninginstrumente. Univariate Varianzanalysen wurden eingesetzt, um Gruppenunterschiede in den arbeitsbezogenen Verhaltens- und Erlebensmustern zu beurteilen. Der AVEM erfasst auf 11 Dimensionen gesundheitsförderliche bzw. -gefährdende Verhaltens- und Erlebensweisen bei der Bewältigung von Arbeits- und Berufsanforderungen.

Ergebnisse Auf 8 von 11 AVEM-Dimensionen zeigten sich signifikante Unterschiede zwischen den Gruppen „kein Verdacht“ und „kPTBS“. Die Gruppen „PTBS“ und „kPTBS“ unterscheiden sich signifikant auf den Dimensionen „Resignationstendenzen“, „Offensive Problembewältigung“ und „Lebenszufriedenheit“. Die Gruppen „kein Verdacht“ und „PTBS“ unterschieden sich hingegen nicht signifikant.

Diskussion Patienten mit Verdacht auf kPTBS stellen im Arbeitskontext eine besonders belastete Patientengruppe dar. Es erscheint inhaltlich plausibel, dass die in der ICD-11 für die kPTBS formulierten Probleme im Bereich der Selbstorganisation zu den gefundenen problematischen Verhaltens- und Erlebensmuster führen können.

Schlussfolgerung Dies spricht dafür, dass für Patienten mit kPTBS spezielle Interventionen im Rahmen der medizinisch-beruflich orientierten Rehabilitation sinnvoll sind, um diese Defizite zu kompensieren und die Teilhabe am Erwerbsleben zu erhalten.
Electrical Cardiometry and Cardiac Biomarkers in 24-h and 48-h Ultramarathoners
Authors: Liu Che-Hung , Li Li-Hua , Chang Ming-Long , Kao Wei-Fong , How Chorng-Kuang , Lai Jiun-I , Lin Yen-Kuang , Chiu Yu-Hui , Chang Wen-Han
Published: March 2021

Our study aimed to (i) utilize novel electrical cardiometry and observe acute changes in cardiac biomarkers among 24-h and 48-h ultra-marathoners, and (ii) examine whether alterations in cardiac responses were associated with the average running speed of these participants. Twenty-four 24-h and sixteen 48-h ultra-marathoners were recruited. Electrical cardiometry in the 2 groups showed significant post-race drops in systolic pressure (24-h: p=0.001; 48-h: p=0.016) and rapid increases in heart rate (24-h, p=0.004; 48-h, p=0.001). Cardiac output increased in 48-h runners (p=0.012) and stroke volume decreased in 24-h runners (p=0.009) at post-test. Six of 20 (30%) 24-h and 4 of 16 (25%) 48-h runners had high-sensitivity troponin T values above the reference interval after the races. N-terminal proB-type natriuretic peptide levels showed a 15-fold increase in 24-h runners and a 10-fold increase in 48-h runners at post-race. There was a positive correlation between delta N-terminal proB-type natriuretic peptide and running mileage (rs=0.629, p=0.003) in 24-h ultra-marathoners. In conclusion, stroke volume and cardiac output showed inconsistent changes between the 2 groups. Average running speed has a significant effect on post-exercise elevation in cardiac biomarkers.
High-Dose Epinephrine Enhances Platelet Aggregation at the Expense of Procoagulant Activity
Authors: Aliotta Alessandro , Bertaggia Calderara Debora , Zermatten Maxime G. , Alberio Lorenzo
Published: March 2021

Platelet activation is characterized by shape change, granule secretion, activation of fibrinogen receptor (glycoprotein IIb/IIIa) sustaining platelet aggregation, and externalization of negatively charged aminophospholipids contributing to platelet procoagulant activity. Epinephrine (EPI) alone is a weak platelet activator. However, it is able to potentiate platelet activation initiated by other agonists. In this work, we investigated the role of EPI in the generation of procoagulant platelets. Human platelets were activated with convulxin (CVX), thrombin (THR) or protease-activated receptor (PAR) agonists, EPI, and combination thereof. Platelet aggregation was assessed by light transmission aggregometry or with PAC-1 binding by flow cytometry. Procoagulant collagen-and-THR (COAT) platelets, induced by combined activation with CVX-and-THR, were visualized by flow cytometry as Annexin-V-positive and PAC-1-negative platelets. Cytosolic calcium fluxes were monitored by flow cytometry using Fluo-3 indicator. EPI increased platelet aggregation induced by all agonist combinations tested. On the other hand, EPI dose-dependently reduced the formation of procoagulant COAT platelets generated by combined CVX-and-THR activation. We observed a decreased Annexin-V-positivity and increased binding of PAC-1 with the triple activation (CVX + THR + EPI) compared with CVX + THR. Calcium mobilization with triple activation was decreased with the higher EPI dose (1,000 µM) compared with CVX + THR calcium kinetics. In conclusion, when platelets are activated with CVX-and-THR, the addition of increasing concentrations of EPI (triple stimulation) modulates platelet response reducing cytosolic calcium mobilization, decreasing procoagulant activity, and enhancing platelet aggregation.
A Single-Center Experience with the Olympus ORBEYE 4K-3D Exoscope for Microsurgery of Complex Cranial Cases: Technical Nuances and Learning Curve
Authors: Muscas Giovanni , Battista Francesca , Boschi Andrea , Morone Francesca , Della Puppa Alessandro
Published: March 2021

Background The introduction of exoscopes in neurosurgery has been welcomed due to their maneuverability, ergonomics, and low-profile frame. 3D devices have further enabled a better stereoscopic visualization. Reports on their application, albeit more and more frequent, are still at their beginning stages. We present our experience with the Olympus ORBEYE 4K-3D exoscope for major cranial procedures. The strengths and weaknesses of the exoscope are presented, and the nuances associated with the learning curve are illustrated.

Methods Over 2 weeks, patients undergoing surgery for major cranial pathologies were offered to participate in this evaluation of the Olympus ORBEYE 4K-3D exoscope. Information on the use of the exoscope was collected to assess the features and struggles in the learning curve. A comparison with the operating microscope was made.

Results Fourteen patients with different intracranial pathologies were operated on with the exoscope. No surgery-related complications occurred. The microsurgical part was performed with the exoscope in six cases. The exoscope was used for 72.9% (±37.5%) of the whole microsurgical time vs. 27.1% (±37.5%) microscope time (p = 0.02).

Conclusion The Olympus ORBEYE 4K-3D exoscope represents a useful evolution of the operating microscope. It requires time to overcome potential difficulties, mostly related to previous motor schemes acquired with operating microscopes. Its features could represent the basis for a paradigm shift in microsurgery.