bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 2 from Phenotypic Reversion of Invasive Neurofibromin-Deficient Schwannoma by FTS: Ras Inhibition Reduces BMP4/Erk/Smad Signaling
Authors: Barkan Batya , Kloog Yoel , Ehrlich Marcelo
Published: April 2023

Supplementary Figure 2 from Phenotypic Reversion of Invasive Neurofibromin-Deficient Schwannoma by FTS: Ras Inhibition Reduces BMP4/Erk/Smad Signaling
Supplementary Figure Legend from In Situ Vaccination with CD204 Gene-Silenced Dendritic Cell, not Unmodified Dendritic Cell, Enhances Radiation Therapy of Prostate Cancer
Authors: Guo Chunqing , Yi Huanfa , Yu Xiaofei , Zuo Daming , Qian Jie , Yang Gary , Foster Barbara A. , Subjeck John R. , Sun Xiaolei , Mikkelsen Ross B. , Fisher Paul B. , Wang Xiang-Yang
Published: April 2023

PDF file, 103K.
Supplementary Table 1 from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Authors: Riffell Jenna L. , Jänicke Reiner U. , Roberge Michel
Published: April 2023

Supplementary Table 1 from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Supplementary Figure Legends 1-6 from Obatoclax Interacts Synergistically with the Irreversible Proteasome Inhibitor Carfilzomib in GC- and ABC-DLBCL Cells In Vitro and In Vivo
Authors: Dasmahapatra Girija , Lembersky Dmitry , Son Minkyeong P. , Patel Hiral , Peterson Derick , Attkisson Elisa , Fisher Richard I. , Friedberg Jonathan W. , Dent Paul , Grant Steven
Published: April 2023

PDF file - 30K
Supplementary Figure 3 from Novel Irreversible Small Molecule Inhibitors of Replication Protein A Display Single-Agent Activity and Synergize with Cisplatin
Authors: Neher Tracy M. , Bodenmiller Diane , Fitch Richard W. , Jalal Shadia I. , Turchi John J.
Published: April 2023

PDF file - 123K
Supplementary Table Legends 1-5 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Authors: Santer Frédéric R. , Höschele Philipp P.S. , Oh Su Jung , Erb Holger H.H. , Bouchal Jan , Cavarretta Ilaria T. , Parson Walther , Meyers David J. , Cole Philip A. , Culig Zoran
Published: April 2023

Supplementary Table Legends 1-5 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Supplementary Figure 1 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Authors: Santer Frédéric R. , Höschele Philipp P.S. , Oh Su Jung , Erb Holger H.H. , Bouchal Jan , Cavarretta Ilaria T. , Parson Walther , Meyers David J. , Cole Philip A. , Culig Zoran
Published: April 2023

Supplementary Figure 1 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Supplementary Methods from Selective Targeting of Interferon γ to Stromal Fibroblasts and Pericytes as a Novel Therapeutic Approach to Inhibit Angiogenesis and Tumor Growth
Authors: Bansal Ruchi , Tomar Tushar , Östman Arne , Poelstra Klaas , Prakash Jai
Published: April 2023

PDF file, 77K, Quantitative PCR, synthesis of pPB-HSA-IFNy and immunostaining methods.
Supplementary Table 2 from Expression Signatures of the Lipid-Based Akt Inhibitors Phosphatidylinositol Ether Lipid Analogues in NSCLC Cells
Authors: Zhang Chunyu , Elkahloun Abdel G. , Liao Hongling , Delaney Shannon , Saber Barbara , Morrow Betsy , Prendergast George C. , Hollander M. Christine , Gills Joell J. , Dennis Phillip A.
Published: April 2023

Supplementary Table 2 from Expression Signatures of the Lipid-Based Akt Inhibitors Phosphatidylinositol Ether Lipid Analogues in NSCLC Cells
Supplementary Figure Legend from Selective Targeting of Interferon γ to Stromal Fibroblasts and Pericytes as a Novel Therapeutic Approach to Inhibit Angiogenesis and Tumor Growth
Authors: Bansal Ruchi , Tomar Tushar , Östman Arne , Poelstra Klaas , Prakash Jai
Published: April 2023

PDF file, 94K.
Supplementary Figure 4 from Selective Targeting of Interferon γ to Stromal Fibroblasts and Pericytes as a Novel Therapeutic Approach to Inhibit Angiogenesis and Tumor Growth
Authors: Bansal Ruchi , Tomar Tushar , Östman Arne , Poelstra Klaas , Prakash Jai
Published: April 2023

PDF file, 221K, Body weight of mice after the treatment with PBS, IFNγ, pPB-HSA-IFNγ and pPB-HSA in B16 tumor-bearing mice.
Supplementary Figure Legends from Spliceosome-Mediated RNA Trans-Splicing Facilitates Targeted Delivery of Suicide Genes to Cancer Cells
Authors: Gruber Christina , Gratz Iris K. , Murauer Eva M. , Mayr Elisabeth , Koller Ulrich , Bruckner-Tuderman Leena , Meneguzzi Guerrino , Hintner Helmut , Bauer Johann W.
Published: April 2023

Supplementary Figure Legends from Spliceosome-Mediated RNA Trans-Splicing Facilitates Targeted Delivery of Suicide Genes to Cancer Cells
Supplementary Figure 4 from The NEDD8-Activating Enzyme Inhibitor, MLN4924, Cooperates with TRAIL to Augment Apoptosis through Facilitating c-FLIP Degradation in Head and Neck Cancer Cells
Authors: Zhao Liqun , Yue Ping , Lonial Sagar , Khuri Fadlo R. , Sun Shi-Yong
Published: April 2023

PDF file - 183K
Supplementary Figure 2 from Antitumor Activity of the Hsp90 Inhibitor IPI-504 in HER2-Positive Trastuzumab-Resistant Breast Cancer
Authors: Scaltriti Maurizio , Serra Violeta , Normant Emmanuel , Guzman Marta , Rodriguez Olga , Lim Alice R. , Slocum Kelly L. , West Kip A. , Rodriguez Varenka , Prudkin Ludmila , Jimenez José , Aura Claudia , Baselga José
Published: April 2023

Supplementary Figure 2 from Antitumor Activity of the Hsp90 Inhibitor IPI-504 in HER2-Positive Trastuzumab-Resistant Breast Cancer
Supplementary Figure 3 from The NEDD8-Activating Enzyme Inhibitor, MLN4924, Cooperates with TRAIL to Augment Apoptosis through Facilitating c-FLIP Degradation in Head and Neck Cancer Cells
Authors: Zhao Liqun , Yue Ping , Lonial Sagar , Khuri Fadlo R. , Sun Shi-Yong
Published: April 2023

PDF file - 137K
Supplementary Table 1 from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
Authors: Natoni Alessandro , Murillo Laura S. , Kliszczak Anna E. , Catherwood Mark A. , Montagnoli Alessia , Samali Afshin , O'Dwyer Michael , Santocanale Corrado
Published: April 2023

XLS file - 37K
Supplementary Methods from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
Authors: Natoni Alessandro , Murillo Laura S. , Kliszczak Anna E. , Catherwood Mark A. , Montagnoli Alessia , Samali Afshin , O'Dwyer Michael , Santocanale Corrado
Published: April 2023

PDF file - 113K
Supplementary Figure Legends and Supplementary Methods Section from NF-κB Is Required for Smac Mimetic-Mediated Sensitization of Glioblastoma Cells for γ-Irradiation–Induced Apoptosis
Authors: Berger Rebecca , Jennewein Claudia , Marschall Viola , Karl Sabine , Cristofanon Silvia , Wagner Liane , Vellanki Sri HariKrishna , Hehlgans Stephanie , Rödel Franz , Debatin Klaus-Michael , Ludolph Albert C. , Fulda Simone
Published: April 2023

PDF file-82KB
Supplementary Tables 1-2 from The Clinically Active PARP Inhibitor AG014699 Ameliorates Cardiotoxicity but Does Not Enhance the Efficacy of Doxorubicin, despite Improving Tumor Perfusion and Radiation Response in Mice
Authors: Ali Majid , Kamjoo Marzieh , Thomas Huw D. , Kyle Suzanne , Pavlovska Ivanda , Babur Muhammed , Telfer Brian A. , Curtin Nicola J. , Williams Kaye J.
Published: April 2023

PDF file - 41K
Supplementary Figure 3 from SAR131675, a Potent and Selective VEGFR-3–TK Inhibitor with Antilymphangiogenic, Antitumoral, and Antimetastatic Activities
Authors: Alam Antoine , Blanc Isabelle , Gueguen-Dorbes Geneviève , Duclos Olivier , Bonnin Jacques , Barron Pauline , Laplace Marie-Claude , Morin Gaelle , Gaujarengues Florence , Dol Frédérique , Hérault Jean-Pascal , Schaeffer Paul , Savi Pierre , Bono Françoise
Published: April 2023

PDF file - 269K, This file shows immunohistological illustrations for blood and lymphatic vessels, for lymph nodes osteopontin and for macrophages
Supplementary Figure 1 from A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface
Authors: Tang Zhewei , Feng Mingqian , Gao Wei , Phung Yen , Chen Weizao , Chaudhary Amit , Croix Brad St. , Qian Min , Dimitrov Dimiter S. , Ho Mitchell
Published: April 2023

PDF file - 1308K, Production and analysis of the SD1-based recombinant immunotoxin.
Supplementary Table 2 from Small-Molecule Inhibitor BMS-777607 Induces Breast Cancer Cell Polyploidy with Increased Resistance to Cytotoxic Chemotherapy Agents
Authors: Sharma Sharad , Zeng Jun-Ying , Zhuang Chun-Mei , Zhou Yong-Qing , Yao Hang-Ping , Hu Xing , Zhang Ruiwen , Wang Ming-Hai
Published: April 2023

PDF file - 57K, Supplementary Table 2 Increased resistance of BMS-777607-induced breast cancer polyploid cells in response to cytotoxic chemotherapy agents.
Supplementary Methods from Antitumor Activity of Saracatinib (AZD0530), a c-Src/Abl Kinase Inhibitor, Alone or in Combination with Chemotherapeutic Agents in Gastric Cancer
Authors: Nam Hyun-Jin , Im Seock-Ah , Oh Do-Youn , Elvin Paul , Kim Hwang-Phill , Yoon Young-Kwang , Min Ahrum , Song Sang-Hyun , Han Sae-Won , Kim Tae-You , Bang Yung-Jue
Published: April 2023

PDF file - 103K
Supplementary Figure and Table Legend from Axl Mediates Acquired Resistance of Head and Neck Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Erlotinib
Authors: Giles Keith M. , Kalinowski Felicity C. , Candy Patrick A. , Epis Michael R. , Zhang Priscilla M. , Redfern Andrew D. , Stuart Lisa M. , Goodall Gregory J. , Leedman Peter J.
Published: April 2023

PDF - 101KB, Legends for Supplemental Figures 1 through 6 and Supplemental Tables 1 through 4.
Supplementary Tables from Overexpression of Asparagine Synthetase and Matrix Metalloproteinase 19 Confers Cisplatin Sensitivity in Nasopharyngeal Carcinoma Cells
Authors: Liu Ran-Yi , Dong Zizheng , Liu Jianguo , Zhou Ling , Huang Wenlin , Khoo Sok Kean , Zhang Zhongfa , Petillo David , Teh Bin Tean , Qian Chao-Nan , Zhang Jian-Ting
Published: April 2023

PDF file, 24K, Table S1. SiRNA sequences; Table S2. Primer sequences.
Supplementary Figure 5 from Axl Mediates Acquired Resistance of Head and Neck Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Erlotinib
Authors: Giles Keith M. , Kalinowski Felicity C. , Candy Patrick A. , Epis Michael R. , Zhang Priscilla M. , Redfern Andrew D. , Stuart Lisa M. , Goodall Gregory J. , Leedman Peter J.
Published: April 2023

PDF - 47KB, Supplementary Figure S5. Sensitivity of HN5-ER cells to erlotinib following Axl knockdown by RNAi.
Supplementary Methods, Figure Legends 1-5 from Apigenin Induces Apoptosis in Human Leukemia Cells and Exhibits Anti-Leukemic Activity In Vivo
Authors: Budhraja Amit , Gao Ning , Zhang Zhuo , Son Young-Ok , Cheng Senping , Wang Xin , Ding Songze , Hitron Andrew , Chen Gang , Luo Jia , Shi Xianglin
Published: April 2023

PDF file - 109K
Supplementary Figure 5 from Apigenin Induces Apoptosis in Human Leukemia Cells and Exhibits Anti-Leukemic Activity In Vivo
Authors: Budhraja Amit , Gao Ning , Zhang Zhuo , Son Young-Ok , Cheng Senping , Wang Xin , Ding Songze , Hitron Andrew , Chen Gang , Luo Jia , Shi Xianglin
Published: April 2023

PDF file - 2.2MB
Supplementary Figure 1 from Axl Mediates Acquired Resistance of Head and Neck Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Erlotinib
Authors: Giles Keith M. , Kalinowski Felicity C. , Candy Patrick A. , Epis Michael R. , Zhang Priscilla M. , Redfern Andrew D. , Stuart Lisa M. , Goodall Gregory J. , Leedman Peter J.
Published: April 2023

PDF - 22KB, Supplementary Figure S1. Cross-resistance of HN5-ER cells to gefitinib and stability of erlotinib resistance in HN5-ER cells grown in the absence of erlotinib.
Supplementary Figures 1-5 from Inhibition of Mutant GNAQ Signaling in Uveal Melanoma Induces AMPK-Dependent Autophagic Cell Death
Authors: Ambrosini Grazia , Musi Elgilda , Ho Alan L. , de Stanchina Elisa , Schwartz Gary K.
Published: April 2023

PDF File - 542K, Effect of GNAQ knockdown on downstream signaling pathways. 92.1 cells were transfected with control (Ctr) and GNAQ siRNA (Gq3) as in Materials and Methods
Supplementary Figure 5 from GX15-070 (Obatoclax) Induces Apoptosis and Inhibits Cathepsin D- and L–Mediated Autophagosomal Lysis in Antiestrogen-Resistant Breast Cancer Cells
Authors: Schwartz-Roberts Jessica L. , Shajahan Ayesha N. , Cook Katherine L. , Wärri Anni , Abu-Asab Mones , Clarke Robert
Published: April 2023

Supplementary Figure 5 PDF file - 51K, Cathepsin mRNA expression is unaffected by GX exposure
Supplementary Figure 4 from Tumor Suppressor MicroRNA-493 Decreases Cell Motility and Migration Ability in Human Bladder Cancer Cells by Downregulating RhoC and FZD4
Authors: Ueno Koji , Hirata Hiroshi , Majid Shahana , Yamamura Soichiro , Shahryari Varahram , Tabatabai Z. Laura , Hinoda Yuji , Dahiya Rajvir
Published: April 2023

PDF file - 8MB
Supplementary Figure Legend from Antitumor Activity of Triolimus: A Novel Multidrug-Loaded Micelle Containing Paclitaxel, Rapamycin, and 17-AAG
Authors: Hasenstein Jason R. , Shin Ho-Chul , Kasmerchak Kelsey , Buehler Darya , Kwon Glen S. , Kozak Kevin R.
Published: April 2023

PDF file, 66K.
Supplementary Figure 3 from Tumor Suppressor MicroRNA-493 Decreases Cell Motility and Migration Ability in Human Bladder Cancer Cells by Downregulating RhoC and FZD4
Authors: Ueno Koji , Hirata Hiroshi , Majid Shahana , Yamamura Soichiro , Shahryari Varahram , Tabatabai Z. Laura , Hinoda Yuji , Dahiya Rajvir
Published: April 2023

PDF file - 140K
Supplementary Figure 4 from Inhibition of p38 MAPK-Dependent Excision Repair Cross-Complementing 1 Expression Decreases the DNA Repair Capacity to Sensitize Lung Cancer Cells to Etoposide
Authors: Tsai Min-Shao , Weng Shao-Hsing , Chen Huang-Jen , Chiu Yu-Fan , Huang Yu-Ching , Tseng Sheng-Chieh , Kuo Ya-Hsun , Lin Yun-Wei
Published: April 2023

PDF file - 573K
Supplementary Figure 4 from Crizotinib, a c-Met Inhibitor, Prevents Metastasis in a Metastatic Uveal Melanoma Model
Authors: Surriga Oliver , Rajasekhar Vinagolu K. , Ambrosini Grazia , Dogan Yildrim , Huang Ruimin , Schwartz Gary K.
Published: April 2023

PDF file - 247K, Supplementary Figure 4: Dose escalation of crizotinib in the xenograft model.
Supplementary Figure 3 from Crizotinib, a c-Met Inhibitor, Prevents Metastasis in a Metastatic Uveal Melanoma Model
Authors: Surriga Oliver , Rajasekhar Vinagolu K. , Ambrosini Grazia , Dogan Yildrim , Huang Ruimin , Schwartz Gary K.
Published: April 2023

PDF file - 124K, Supplementary Figure 3: Crizotinib toxicity in uveal melanoma xenograft studies.
Supplementary Figure 2 from Crizotinib, a c-Met Inhibitor, Prevents Metastasis in a Metastatic Uveal Melanoma Model
Authors: Surriga Oliver , Rajasekhar Vinagolu K. , Ambrosini Grazia , Dogan Yildrim , Huang Ruimin , Schwartz Gary K.
Published: April 2023

PDF file - 786K, Supplementary Figure 2: Effects of c-Met inhibition by a higher dose of crizotinib on cell migration.
Supplementary Data 2 from Inhibition of p38 MAPK-Dependent Excision Repair Cross-Complementing 1 Expression Decreases the DNA Repair Capacity to Sensitize Lung Cancer Cells to Etoposide
Authors: Tsai Min-Shao , Weng Shao-Hsing , Chen Huang-Jen , Chiu Yu-Fan , Huang Yu-Ching , Tseng Sheng-Chieh , Kuo Ya-Hsun , Lin Yun-Wei
Published: April 2023

PDF file - 177K, 17-AAG structure.
Supplementary Figure 1 from Crizotinib, a c-Met Inhibitor, Prevents Metastasis in a Metastatic Uveal Melanoma Model
Authors: Surriga Oliver , Rajasekhar Vinagolu K. , Ambrosini Grazia , Dogan Yildrim , Huang Ruimin , Schwartz Gary K.
Published: April 2023

PDF file - 805K, Supplementary Figure 1: Effects of c-Met, ALK and ROS1 knockdown by siRNA on cell migration.
Supplementary Table 4 from An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735
Authors: Hook Kenneth E. , Garza Scott J. , Lira Maruja E. , Ching Keith A. , Lee Nathan V. , Cao Joan , Yuan Jing , Ye Jingjing , Ozeck Mark , Shi Stephanie T. , Zheng Xianxian , Rejto Paul A. , Kan Julie L.C. , Christensen James G. , Pavlicek Adam
Published: April 2023

PDF file - 186K
Supplementary Figure 1 from Targeting Olfactomedin-like 3 Inhibits Tumor Growth by Impairing Angiogenesis and Pericyte Coverage
Authors: Miljkovic-Licina Marijana , Hammel Philippe , Garrido-Urbani Sarah , Lee Boris P.-L. , Meguenani Mehdi , Chaabane Chiraz , Bochaton-Piallat Marie-Luce , Imhof Beat A.
Published: April 2023

PDF file - 1500K, Olfml3 upregulation in angiogenic endothelium
Supplementary Figure 2 from An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735
Authors: Hook Kenneth E. , Garza Scott J. , Lira Maruja E. , Ching Keith A. , Lee Nathan V. , Cao Joan , Yuan Jing , Ye Jingjing , Ozeck Mark , Shi Stephanie T. , Zheng Xianxian , Rejto Paul A. , Kan Julie L.C. , Christensen James G. , Pavlicek Adam
Published: April 2023

PDF file - 216K
Supplementary Figure Legend from Antitumor Mechanisms of Targeting the PDK1 Pathway in Head and Neck Cancer
Authors: Bhola Neil E. , Freilino Maria L. , Joyce Sonali C. , Sen Malabika , Thomas Sufi M. , Sahu Anirban , Cassell Andre , Chen Ching-Shih , Grandis Jennifer R.
Published: April 2023

PDF File, 77KB.
Supplementary Video 3 from Low-Dose Metronomic Oral Dosing of a Prodrug of Gemcitabine (LY2334737) Causes Antitumor Effects in the Absence of Inhibition of Systemic Vasculogenesis
Authors: Francia Giulio , Shaked Yuval , Hashimoto Kae , Sun John , Yin Melissa , Cesta Carolyn , Xu Ping , Man Shan , Hackl Christina , Stewart Julie , Uhlik Mark , Dantzig Anne H. , Foster F. Stuart , Kerbel Robert S.
Published: April 2023

AVI file - 4.9MB
Supplementary Figure 3 from Antitumor Mechanisms of Targeting the PDK1 Pathway in Head and Neck Cancer
Authors: Bhola Neil E. , Freilino Maria L. , Joyce Sonali C. , Sen Malabika , Thomas Sufi M. , Sahu Anirban , Cassell Andre , Chen Ching-Shih , Grandis Jennifer R.
Published: April 2023

PDF file, 453KB, PDK1 contributes to HNSCC sensitivity to AR-12.
Supplementary Figure 2 from Low-Dose Metronomic Oral Dosing of a Prodrug of Gemcitabine (LY2334737) Causes Antitumor Effects in the Absence of Inhibition of Systemic Vasculogenesis
Authors: Francia Giulio , Shaked Yuval , Hashimoto Kae , Sun John , Yin Melissa , Cesta Carolyn , Xu Ping , Man Shan , Hackl Christina , Stewart Julie , Uhlik Mark , Dantzig Anne H. , Foster F. Stuart , Kerbel Robert S.
Published: April 2023

PDF file - 6.5MB
Supplementary Methods, Figure Legends 1-8, Tables 1-4 from NMS-P937, an Orally Available, Specific Small-Molecule Polo-like Kinase 1 Inhibitor with Antitumor Activity in Solid and Hematologic Malignancies
Authors: Valsasina Barbara , Beria Italo , Alli Cristina , Alzani Rachele , Avanzi Nilla , Ballinari Dario , Cappella Paolo , Caruso Michele , Casolaro Alessia , Ciavolella Antonella , Cucchi Ulisse , De Ponti Anna , Felder Eduard , Fiorentini Francesco , Galvani Arturo , Gianellini Laura M. , Giorgini Maria L. , Isacchi Antonella , Lansen Jaqueline , Pesenti Enrico , Rizzi Simona , Rocchetti Maurizio , Sola Francesco , Moll Jürgen
Published: April 2023

PDF file - 213K
Supplementary Figure 2 from Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts
Authors: Anbalagan Muralidharan , Ali Alaa , Jones Ryan K. , Marsden Carolyn G. , Sheng Mei , Carrier Latonya , Bu Yahao , Hangauer David , Rowan Brian G.
Published: April 2023

PDF file, 55K, Effect of KX-01 alone on MDA-MB-157 tumor xenograft and in combination with doxorubicin in both MDA-MB-231 and MDA-MB-157 xenografts in Nude mice.
Supplementary Table 4 from Prognostic Role of Lemur Tyrosine Kinase-3 Germline Polymorphisms in Adjuvant Gastric Cancer in Japan and the United States
Authors: Wakatsuki Takeru , LaBonte Melissa J. , Bohanes Pierre O. , Zhang Wu , Yang Dongyun , Azuma Mizutomo , Barzi Afsaneh , Ning Yan , Loupakis Fotios , Saadat Siamak , Volz Nico , Stintzing Sebastian , El-Khoueiry Rita , Koizumi Wasaburo , Watanabe Masahiko , Shah Manish , Stebbing Justin , Giamas Georgios , Lenz Heinz-Josef
Published: April 2023

PDF - 86K, Plasma estradiol (E2) levels and body mass index comparison between males and females in the Japanese and US cohorts.
Supplementary Table 3 from Prognostic Role of Lemur Tyrosine Kinase-3 Germline Polymorphisms in Adjuvant Gastric Cancer in Japan and the United States
Authors: Wakatsuki Takeru , LaBonte Melissa J. , Bohanes Pierre O. , Zhang Wu , Yang Dongyun , Azuma Mizutomo , Barzi Afsaneh , Ning Yan , Loupakis Fotios , Saadat Siamak , Volz Nico , Stintzing Sebastian , El-Khoueiry Rita , Koizumi Wasaburo , Watanabe Masahiko , Shah Manish , Stebbing Justin , Giamas Georgios , Lenz Heinz-Josef
Published: April 2023

PDF - 62K, Breakdown by genotype of the LMTK3 polymorphisms analyzed and their correlation with survival (disease-free survival and overall survival) in the Japanese and US cohorts.
Supplementary Tables 1-4 from Autophagy Inhibition Synergistically Enhances Anticancer Efficacy of RAMBA, VN/12-1 in SKBR-3 Cells, and Tumor Xenografts
Authors: Godbole Abhijit M. , Purushottamachar Puranik , Martin Marlena S. , Daskalakis Constantine , Njar Vincent C.O.
Published: April 2023

PDF file - 99K
Supplementary Table Legends 1-4 from Autophagy Inhibition Synergistically Enhances Anticancer Efficacy of RAMBA, VN/12-1 in SKBR-3 Cells, and Tumor Xenografts
Authors: Godbole Abhijit M. , Purushottamachar Puranik , Martin Marlena S. , Daskalakis Constantine , Njar Vincent C.O.
Published: April 2023

PDF file - 67K
Supplementary Figure 1 from Interaction of the Sympathetic Nerve with Pancreatic Cancer Cells Promotes Perineural Invasion through the Activation of STAT3 Signaling
Authors: Guo Kun , Ma Qingyong , Li Junhui , Wang Zheng , Shan Tao , Li Wei , Xu Qinhong , Xie Keping
Published: April 2023

PDF file, 45KB, Effects of beta-AR antagonists on PNI
Supplementary Materials and Methods from Autophagy Inhibition Synergistically Enhances Anticancer Efficacy of RAMBA, VN/12-1 in SKBR-3 Cells, and Tumor Xenografts
Authors: Godbole Abhijit M. , Purushottamachar Puranik , Martin Marlena S. , Daskalakis Constantine , Njar Vincent C.O.
Published: April 2023

PDF file - 92K
Supplementary Figure 7 from Smoking Induces Epithelial-to-Mesenchymal Transition in Non–Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin
Authors: Nagathihalli Nagaraj S. , Massion Pierre P. , Gonzalez Adriana L. , Lu Pengcheng , Datta Pran K.
Published: April 2023

PDF file, 97K, Role of LEF-1 and Slug knockdown cells on cell migration and proliferation.
Supplementary Figure 6 from Smoking Induces Epithelial-to-Mesenchymal Transition in Non–Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin
Authors: Nagathihalli Nagaraj S. , Massion Pierre P. , Gonzalez Adriana L. , Lu Pengcheng , Datta Pran K.
Published: April 2023

PDF file, 179K, Regulation of E-cadh, LEF-1 and Slug expression in knockdown LEF-1 and Slug cells treated with MS-275.
Supplementary Table 1 from Pharmacogenomic Profiling and Pathway Analyses Identify MAPK-Dependent Migration as an Acute Response to SN38 in p53 Null and p53-Mutant Colorectal Cancer Cells
Authors: Allen Wendy L. , Turkington Richard C. , Stevenson Leanne , Carson Gail , Coyle Vicky M. , Hector Suzanne , Dunne Philip , Van Schaeybroeck Sandra , Longley Daniel B. , Johnston Patrick G.
Published: April 2023

PDF file - 132K, List showing 752 genes that are commonly altered following SN38 treatment over time in isogenic HCT116 p53wild-type and HCT116 p53null cells. Genes have been normalised and filtered as stated in the materials and methods
Supplementary Figure Legend from CTLA-4 Blockade Expands Infiltrating T Cells and Inhibits Cancer Cell Repopulation during the Intervals of Chemotherapy in Murine Mesothelioma
Authors: Wu Licun , Yun Zhihong , Tagawa Tetsuzo , Rey-McIntyre Katrina , de Perrot Marc
Published: April 2023

PDF file, 76KB.
Supplementary Figure 2 from CTLA-4 Blockade Expands Infiltrating T Cells and Inhibits Cancer Cell Repopulation during the Intervals of Chemotherapy in Murine Mesothelioma
Authors: Wu Licun , Yun Zhihong , Tagawa Tetsuzo , Rey-McIntyre Katrina , de Perrot Marc
Published: April 2023

PDF file, 41KB, Response of murine mesothelioma to serial treatments with cisplatin.
Supplementary Table 2 from A 71-Gene Signature of TRAIL Sensitivity in Cancer Cells
Authors: Chen Jun-Jie , Knudsen Steen , Mazin Wiktor , Dahlgaard Jesper , Zhang Baolin
Published: April 2023

PDF file - 60K, Supplement II.
Supplementary Table 1-2 from Effects of Anti-VEGF on Pharmacokinetics, Biodistribution, and Tumor Penetration of Trastuzumab in a Preclinical Breast Cancer Model
Authors: Pastuskovas Cinthia V. , Mundo Eduardo E. , Williams Simon P. , Nayak Tapan K. , Ho Jason , Ulufatu Sheila , Clark Suzanna , Ross Sarajane , Cheng Eric , Parsons-Reponte Kathryn , Cain Gary , Van Hoy Marjie , Majidy Nicholas , Bheddah Sheila , dela Cruz Chuh Josefa , Kozak Katherine R. , Lewin-Koh Nicholas , Nauka Peter , Bumbaca Daniela , Sliwkowski Mark , Tibbitts Jay , Theil Frank-Peter , Fielder Paul J. , Khawli Leslie A. , Boswell C. Andrew
Published: April 2023

PDF file - 87K
Supplementary Figure 1 from Effects of Anti-VEGF on Pharmacokinetics, Biodistribution, and Tumor Penetration of Trastuzumab in a Preclinical Breast Cancer Model
Authors: Pastuskovas Cinthia V. , Mundo Eduardo E. , Williams Simon P. , Nayak Tapan K. , Ho Jason , Ulufatu Sheila , Clark Suzanna , Ross Sarajane , Cheng Eric , Parsons-Reponte Kathryn , Cain Gary , Van Hoy Marjie , Majidy Nicholas , Bheddah Sheila , dela Cruz Chuh Josefa , Kozak Katherine R. , Lewin-Koh Nicholas , Nauka Peter , Bumbaca Daniela , Sliwkowski Mark , Tibbitts Jay , Theil Frank-Peter , Fielder Paul J. , Khawli Leslie A. , Boswell C. Andrew
Published: April 2023

PDF file - 93K
Supplementary Table 2 from An Optical Probe for Noninvasive Molecular Imaging of Orthotopic Brain Tumors Overexpressing Epidermal Growth Factor Receptor
Authors: Agnes Richard S. , Broome Ann-Marie , Wang Jing , Verma Anjali , Lavik Kari , Basilion James P.
Published: April 2023

PDF file, 36K, Physical properties of peptides studied in this report. RP-HPLC conditions 10-60% acetonitrile against 0.1% trifluoroacetic acid over 30 minutes through a C18 column (PROTO 300, 10 micron, 250 x 4.6 mm) where the injection peak at 3.6 min. 5-90% acetonitrile against 0.1% trifluoroacetic acid over 30 minutes through a C18 column (PROTO 200, 5 micron, 250x 10 mm). Injection peak at 6.8 min.
Supplementary Table 1 from An Optical Probe for Noninvasive Molecular Imaging of Orthotopic Brain Tumors Overexpressing Epidermal Growth Factor Receptor
Authors: Agnes Richard S. , Broome Ann-Marie , Wang Jing , Verma Anjali , Lavik Kari , Basilion James P.
Published: April 2023

PDF file, 46K, Peptides were characterized and verified by MALDI mass spectrometry. Table shows the expected and observed molecular weight of the peptides.
Supplementary Figure 1 from An Optical Probe for Noninvasive Molecular Imaging of Orthotopic Brain Tumors Overexpressing Epidermal Growth Factor Receptor
Authors: Agnes Richard S. , Broome Ann-Marie , Wang Jing , Verma Anjali , Lavik Kari , Basilion James P.
Published: April 2023

PDF file, 116K, A) Expression levels of the wild type EGFR determined by Western blot in A431, U87-MG, and Gli36Δ5 cell lines. Cell lysates were derived from each cell type and 50 μg of each separated using SDS-PAGE. The gels were then transferred to nitrocellulose membrane and probed for wild type EGFR (DAKO, Carpenteria, CA, clone DAK-H1-WT). Loading control was determined by blotting against β-actin. B) Quantification of the western blot data from S1A. Protein expression levels of wild type EGFR are represented in log10 scale. A431 cells overexpress wild type EGFR more than 60 and 20-fold relative to U87-MG and Gli36Δ5 cells, respectively. C) Saturation binding assay. Compound 2 was incubated with A431 cells at increasing concentrations for 1 hour, washed, and cell associated Cy5.5 was quantified. The Kd determined for the A431 cell line was 8.0�3.0 μM. D) Cell uptake of compound 2 in the presence of hEGF ligand. A431 cells were plated in 96-well plates and were treated with 1 μM of Cy5.5-EGFpep in the presence of increasing amounts of hEGF (or no treatment) for 90 minutes. Uptake increased with increasing EGF stimulation. These data suggest that uptake of labeled ligand is specific to EGF receptors. *, P>0.01; **, P>001.
Supplementary Figure 2 from The Cannabinoid WIN 55,212-2 Decreases Specificity Protein Transcription Factors and the Oncogenic Cap Protein eIF4E in Colon Cancer Cells
Authors: Sreevalsan Sandeep , Safe Stephen
Published: April 2023

PDF - 488KB, Silencing Myc and p65 does not affect miR-27a expression.
Supplementary Figure 2 from Inhibition of HSP90 with AUY922 Induces Synergy in HER2-Amplified Trastuzumab-Resistant Breast and Gastric Cancer
Authors: Wainberg Zev A. , Anghel Adrian , Rogers Amy M. , Desai Amrita J. , Kalous Ondrej , Conklin Dylan , Ayala Raul , O'Brien Neil A. , Quadt Cornelia , Akimov Mikhail , Slamon Dennis J. , Finn Richard S.
Published: April 2023

Supplementary Figure 2 PDF file - 91K, Speed of recovery of downstream targets in NCI-N87
Supplementary Figure 4 from A Monoclonal Antibody against Human Notch1 Ligand–Binding Domain Depletes Subpopulation of Putative Breast Cancer Stem–like Cells
Authors: Sharma Ankur , Paranjape Anurag N. , Rangarajan Annapoorni , Dighe Rajan R.
Published: April 2023

PDF file - 4MB
Supplementary Figure 3 from The Gamma Secretase Inhibitor MRK-003 Attenuates Pancreatic Cancer Growth in Preclinical Models
Authors: Mizuma Masamichi , Rasheed Zeshaan A. , Yabuuchi Shinichi , Omura Noriyuki , Campbell Nathaniel R. , de Wilde Roeland F. , De Oliveira Elizabeth , Zhang Qing , Puig Oscar , Matsui William , Hidalgo Manuel , Maitra Anirban , Rajeshkumar N.V.
Published: April 2023

PDF file, 209K, Representative H&E stained sections from Panc374 xenograft.
Supplementary Figure 1 from A Monoclonal Antibody against Human Notch1 Ligand–Binding Domain Depletes Subpopulation of Putative Breast Cancer Stem–like Cells
Authors: Sharma Ankur , Paranjape Anurag N. , Rangarajan Annapoorni , Dighe Rajan R.
Published: April 2023

PDF file - 1.5MB
Supplementary Figure Legends 1-2 from The Relationship of Thioredoxin-1 and Cisplatin Resistance: Its Impact on ROS and Oxidative Metabolism in Lung Cancer Cells
Authors: Wangpaichitr Medhi , Sullivan Elizabeth J. , Theodoropoulos George , Wu Chunjing , You Min , Feun Lynn G. , Lampidis Theodore J. , Kuo Macus T. , Savaraj Niramol
Published: April 2023

PDF file - 49K
Supplementary Figure Legend from Molecular Predictors of Sensitivity to the Insulin-like Growth Factor 1 Receptor Inhibitor Figitumumab (CP-751,871)
Authors: Pavlicek Adam , Lira Maruja E. , Lee Nathan V. , Ching Keith A. , Ye Jingjing , Cao Joan , Garza Scott J. , Hook Kenneth E. , Ozeck Mark , Shi Stephanie T. , Yuan Jing , Zheng Xianxian , Rejto Paul A. , Kan Julie L.C. , Christensen James G.
Published: April 2023

PDF file - 62K
Supplementary Table 3 from Therapeutic Mechanism and Efficacy of the Antibody–Drug Conjugate BAY 79-4620 Targeting Human Carbonic Anhydrase 9
Authors: Petrul Heike M. , Schatz Christoph A. , Kopitz Charlotte C. , Adnane Lila , McCabe Timothy J. , Trail Pamela , Ha Sha , Chang Yong S. , Voznesensky Andrei , Ranges Gerald , Tamburini Paul P.
Published: April 2023

PDF file - 68K, Statistical results of in vivo experiments.
Supplementary Table 2 from Therapeutic Mechanism and Efficacy of the Antibody–Drug Conjugate BAY 79-4620 Targeting Human Carbonic Anhydrase 9
Authors: Petrul Heike M. , Schatz Christoph A. , Kopitz Charlotte C. , Adnane Lila , McCabe Timothy J. , Trail Pamela , Ha Sha , Chang Yong S. , Voznesensky Andrei , Ranges Gerald , Tamburini Paul P.
Published: April 2023

PDF file - 79K, Targeted tubulin disruption by BAY 79-4620.
Supplementary Figure 2 from Inducible Silencing of Protein Kinase D3 Inhibits Secretion of Tumor-Promoting Factors in Prostate Cancer
Authors: LaValle Courtney R. , Zhang Liyong , Xu Shuping , Eiseman Julie L. , Wang Q. Jane
Published: April 2023

PDF file, 513KB, Transient knockdown of PKD2 and/or PKD3 reduces migration and invasion in PC3 cells.
Supplementary Figure 1 from Therapeutic Mechanism and Efficacy of the Antibody–Drug Conjugate BAY 79-4620 Targeting Human Carbonic Anhydrase 9
Authors: Petrul Heike M. , Schatz Christoph A. , Kopitz Charlotte C. , Adnane Lila , McCabe Timothy J. , Trail Pamela , Ha Sha , Chang Yong S. , Voznesensky Andrei , Ranges Gerald , Tamburini Paul P.
Published: April 2023

PDF file - 147K, Internalization of anti-CA9 antibody 3ee9.
Supplementary Figure 1 from Selective Photodetection and Photodynamic Therapy for Prostate Cancer through Targeting of Proteolytic Activity
Authors: Zuluaga Maria-Fernanda , Sekkat Nawal , Gabriel Doris , van den Bergh Hubert , Lange Norbert
Published: April 2023

PDF file - 300KB, Bioluminescence imaging of three PCa-xenografted-mice before and 30 days after PDT. Animals bearing subcutaneous prostate tumors were treated with 7.5 mg/kg of uPA-PPP as Pba equivalents and 16 hours after injection, tumors were irradiated with 150 J/cm2 at 665 +/- 5 nm. Images were taken 15 min after intra-peritoneal injection of D-luciferin.
Supplementary Figure 5 from Identification and Characterization of MEL-3, a Novel AR Antagonist That Suppresses Prostate Cancer Cell Growth
Authors: Helsen Christine , Marchand Arnaud , Chaltin Patrick , Munck Sebastian , Voet Arnout , Verstuyf Annemieke , Claessens Frank
Published: April 2023

PDF file, 41KB, MEL-3 does not affect AR mRNA levels in LAPC4 and LNCaP cells.
Supplementary Figure 4 from Identification and Characterization of MEL-3, a Novel AR Antagonist That Suppresses Prostate Cancer Cell Growth
Authors: Helsen Christine , Marchand Arnaud , Chaltin Patrick , Munck Sebastian , Voet Arnout , Verstuyf Annemieke , Claessens Frank
Published: April 2023

PDF file, 58KB, MEL-3 does not induce apoptosis via Caspase-3 activation.
Supplementary Table 1 from Thermal Targeting of an Acid-Sensitive Doxorubicin Conjugate of Elastin-like Polypeptide Enhances the Therapeutic Efficacy Compared with the Parent Compound In Vivo
Authors: Moktan Shama , Perkins Eddie , Kratz Felix , Raucher Drazen
Published: April 2023

PDF file, 69KB, Pharmacokinetics of SynB1-ELP1-Dox.
Supplementary Table 1 from IGFBP2/FAK Pathway Is Causally Associated with Dasatinib Resistance in Non–Small Cell Lung Cancer Cells
Authors: Lu Haibo , Wang Li , Gao Wen , Meng Jieru , Dai Bingbing , Wu Shuhong , Minna John , Roth Jack A. , Hofstetter Wayne L. , Swisher Stephen G. , Fang Bingliang
Published: April 2023

PDF - 35KB, Combination Index for dasatinib and FAK inhibitor PF562271.
Supplementary Figure 7 from Reversing Effect of Ring Finger Protein 43 Inhibition on Malignant Phenotypes of human Hepatocellular Carcinoma
Authors: Xing Chunyang , Zhou Wuhua , Ding Songming , Xie Haiyang , Zhang Wu , Yang Zhe , Wei Bajin , Chen Kangjie , Su Rong , Cheng Jun , Zheng Shusen , Zhou Lin
Published: April 2023

PDF file - 266K, Gene Ontology analysis of differentially expressed genes after RNF43 Knockdown. Gene Ontology analysis was performed using EASE software, the bar indicates if the gene is up- (white) or down- (black) regulated after RNF43 knockdown.
Supplementary Methods and Figure Legends from Hsp90 Inhibitors Promote p53-Dependent Apoptosis through PUMA and Bax
Authors: He Kan , Zheng Xingnan , Zhang Lin , Yu Jian
Published: April 2023

PDF - 169KB
Supplementary Figure 3 from Reversing Effect of Ring Finger Protein 43 Inhibition on Malignant Phenotypes of human Hepatocellular Carcinoma
Authors: Xing Chunyang , Zhou Wuhua , Ding Songming , Xie Haiyang , Zhang Wu , Yang Zhe , Wei Bajin , Chen Kangjie , Su Rong , Cheng Jun , Zheng Shusen , Zhou Lin
Published: April 2023

PDF file - 392K, Knockdown of RNF43 induces apoptosis in HCC cells. (A) At 72 hours after transfection with indicated siRNAs, the effect of RNF43 knockdown on cell apoptosis was assessed by flow cytometry using Annexin V/PI Apoptosis Kit (n=3, **p < 0.01, ***p < 0.001). (B) Protein expression of activated Caspase-3 was evaluated by Western blotting.
Supplementary Figure 6 from Enhancement of Synthetic Lethality via Combinations of ABT-888, a PARP Inhibitor, and Carboplatin In Vitro and In Vivo Using BRCA1 and BRCA2 Isogenic Models
Authors: Clark Caroline C. , Weitzel Jeffrey N. , O'Connor Timothy R.
Published: April 2023

PDF file, 117K, SUPPLEMENTARY FIGURE S6. Apoptosis in mESC after treatment with ABT-888 and carboplatin, singly or in combination. WT, Brca1, and Brca2 mESCs were treated with ABT-888 (0.5 μM) and carboplatin (0.5 μM), singly or in combination. (A) Percentage of apoptotic cells after treatment with ABT- 888, carboplatin or their combination for 48 h. Apoptosis was measured by Annexin V/propidium iodide staining and analyzed by FACS. The percentage of apoptotic cells was obtained by determining the percentage of Annexin V-positive cells. (B) Western blots of Parp1 cleavage after treatment with ABT-888, carboplatin or their combination for the indicated times. The red box indicates cleaved PARP1, which is an indication of apoptosis. Actin served as a loading control.
Supplementary Figure 4 from Enhancement of Synthetic Lethality via Combinations of ABT-888, a PARP Inhibitor, and Carboplatin In Vitro and In Vivo Using BRCA1 and BRCA2 Isogenic Models
Authors: Clark Caroline C. , Weitzel Jeffrey N. , O'Connor Timothy R.
Published: April 2023

PDF file, 371K, SUPPLEMENTARY FIGURE S4. Hematoxylin and Eosin staining (200x magnification) of tumor sections.
Supplementary Figures 1-2, Table 1 from Effective Targeting of Hedgehog Signaling in a Medulloblastoma Model with PF-5274857, a Potent and Selective Smoothened Antagonist That Penetrates the Blood–Brain Barrier
Authors: Rohner Allison , Spilker Mary E. , Lam Justine L. , Pascual Bernadette , Bartkowski Darian , Li Qing John , Yang Amy H. , Stevens Greg , Xu Meirong , Wells Peter A. , Planken Simon , Nair Sajiv , Sun Shaoxian
Published: April 2023

PDF file - 123K
Supplementary Figure 3 from Enhancement of Synthetic Lethality via Combinations of ABT-888, a PARP Inhibitor, and Carboplatin In Vitro and In Vivo Using BRCA1 and BRCA2 Isogenic Models
Authors: Clark Caroline C. , Weitzel Jeffrey N. , O'Connor Timothy R.
Published: April 2023

PDF file, 131K, SUPPLEMENTARY FIGURE S3. Clonogenic cell survival of isogenic VC8 (Brca2-deficient) and VC8+Brca2 (Brca2-complemented) CHO cells after treatment with ABT-888, carboplatin, cisplatin alone or ABT-888 combined with a platinum drug. VC8 and VC8+Brca2 cells were treated for 6 days with the indicated drugs and concentrations. (A) ABT-888, (B) carboplatin, and (C) ABT-888/carboplatin. Data represent the average of triplicate measurements. Error bars, mean + SEM. (D) Interaction effects of ABT-888 with carboplatin treatment in VC8 CHO cell line.
Supplementary Tables 1-2, Figures 1-2 from Sensitivity of Selected Human Tumor Models to PF-04217903, a Novel Selective c-Met Kinase Inhibitor
Authors: Zou Helen Y. , Li Qiuhua , Lee Joseph H. , Arango Maria E. , Burgess Kristina , Qiu Ming , Engstrom Lars D. , Yamazaki Shinji , Parker Max , Timofeevski Sergei , Cui Jingrong Jean , McTigue Michele , Los Gerrit , Bender Steven L. , Smeal Tod , Christensen James G.
Published: April 2023

PDF file - 44K
Supplementary Figure 3 from HDAC Inhibitor Entinostat Restores Responsiveness of Letrozole-Resistant MCF-7Ca Xenografts to Aromatase Inhibitors through Modulation of Her-2
Authors: Sabnis Gauri J. , Goloubeva Olga G. , Kazi Armina A. , Shah Preeti , Brodie Angela H.
Published: April 2023

PDF file - 148K, Supplemental Figure 3: RT-PCR analysis of Her-2 mRNA levels in MCF-7Ca and LTLT-Ca cells.
Supplementary Figure 2 from HDAC Inhibitor Entinostat Restores Responsiveness of Letrozole-Resistant MCF-7Ca Xenografts to Aromatase Inhibitors through Modulation of Her-2
Authors: Sabnis Gauri J. , Goloubeva Olga G. , Kazi Armina A. , Shah Preeti , Brodie Angela H.
Published: April 2023

PDF file - 157K, Supplemental Figure 2: Western blotting analysis of LTLT-Ca cells treated with entinostat in presence of MG-132.
Supplementary Figure 2 from Activation of IL-6R/JAK1/STAT3 Signaling Induces De Novo Resistance to Irreversible EGFR Inhibitors in Non–Small Cell Lung Cancer with T790M Resistance Mutation
Authors: Kim Sun Mi , Kwon Oh-Joon , Hong Yun Kyoung , Kim Joo Hang , Solca Flavio , Ha Sang-Jun , Soo Ross A. , Christensen James G. , Lee Ji Hyun , Cho Byoung Chul
Published: April 2023

PDF file, 19K, Enhancement of afatinib-induced apoptosis by STAT3 knockdown.
Supplementary Table 1 from A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists
Authors: Chenna Venugopal , Hu Chaoxin , Pramanik Dipankar , Aftab Blake T. , Karikari Collins , Campbell Nathaniel R. , Hong Seung-Mo , Zhao Ming , Rudek Michelle A. , Khan Saeed R. , Rudin Charles M. , Maitra Anirban
Published: April 2023

PDF file - 110K
Supplementary Figures 1-5 from Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells
Authors: Zhang Shu , Kim KyoungHyun , Jin Un Ho , Pfent Catherine , Cao Huojun , Amendt Brad , Liu Xinyi , Wilson-Robles Heather , Safe Stephen
Published: April 2023

Supplementary Figures 1-5 from Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells
Supplementary Figure 2 from A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists
Authors: Chenna Venugopal , Hu Chaoxin , Pramanik Dipankar , Aftab Blake T. , Karikari Collins , Campbell Nathaniel R. , Hong Seung-Mo , Zhao Ming , Rudek Michelle A. , Khan Saeed R. , Rudin Charles M. , Maitra Anirban
Published: April 2023

PDF file - 105K
Supplementary Methods, Figure Legends 1-3 from Cigarette Smoke Induces Aberrant EGF Receptor Activation That Mediates Lung Cancer Development and Resistance to Tyrosine Kinase Inhibitors
Authors: Filosto Simone , Becker Cathleen R. , Goldkorn Tzipora
Published: April 2023

PDF file - 94K
Supplementary Figure 4 from A Recombinant Immunotoxin against the Tumor-Associated Antigen Mesothelin Reengineered for High Activity, Low Off-Target Toxicity, and Reduced Antigenicity
Authors: Weldon John E. , Xiang Laiman , Zhang Jingli , Beers Richard , Walker Dawn A. , Onda Masanori , Hassan Raffit , Pastan Ira
Published: April 2023

PDF file - 231K, Human antigenicity of SS1-LR/GGS/8M
Supplementary Figure 2 from Cigarette Smoke Induces Aberrant EGF Receptor Activation That Mediates Lung Cancer Development and Resistance to Tyrosine Kinase Inhibitors
Authors: Filosto Simone , Becker Cathleen R. , Goldkorn Tzipora
Published: April 2023

PDF file - 55K
Supplementary Figure 1 from A Recombinant Immunotoxin against the Tumor-Associated Antigen Mesothelin Reengineered for High Activity, Low Off-Target Toxicity, and Reduced Antigenicity
Authors: Weldon John E. , Xiang Laiman , Zhang Jingli , Beers Richard , Walker Dawn A. , Onda Masanori , Hassan Raffit , Pastan Ira
Published: April 2023

PDF file - 626K, Purified recombinant immunotoxins
Supplementary Table 3 from Effect of Small-Molecule–Binding Affinity on Tumor Uptake In Vivo: A Systematic Study Using a Pretargeted Bispecific Antibody
Authors: Orcutt Kelly Davis , Rhoden John J. , Ruiz-Yi Benjamin , Frangioni John V. , Wittrup K. Dane
Published: April 2023

PDF file - 59K, Four hour Biodistribution of 177Lu-DOTA in tumor mice
Supplementary Figure 1 from Effect of Small-Molecule–Binding Affinity on Tumor Uptake In Vivo: A Systematic Study Using a Pretargeted Bispecific Antibody
Authors: Orcutt Kelly Davis , Rhoden John J. , Ruiz-Yi Benjamin , Frangioni John V. , Wittrup K. Dane
Published: April 2023

PDF file, 85KB, Lu-DOTA organ/tissue biodistribution with and without clearing agent.
Supplementary Figure 7 from Dacomitinib (PF-00299804), an Irreversible Pan-HER Inhibitor, Inhibits Proliferation of HER2-Amplified Breast Cancer Cell Lines Resistant to Trastuzumab and Lapatinib
Authors: Kalous Ondrej , Conklin Dylan , Desai Amrita J. , O'Brien Neil A. , Ginther Charles , Anderson Lee , Cohen David J. , Britten Carolyn D. , Taylor Ian , Christensen James G. , Slamon Dennis J. , Finn Richard S.
Published: April 2023

PDF file, 247K, The effects of dacomitinib on protein expression in lines resistant to trastuzumab and lapatinib.
Supplementary Figure 6 from Dacomitinib (PF-00299804), an Irreversible Pan-HER Inhibitor, Inhibits Proliferation of HER2-Amplified Breast Cancer Cell Lines Resistant to Trastuzumab and Lapatinib
Authors: Kalous Ondrej , Conklin Dylan , Desai Amrita J. , O'Brien Neil A. , Ginther Charles , Anderson Lee , Cohen David J. , Britten Carolyn D. , Taylor Ian , Christensen James G. , Slamon Dennis J. , Finn Richard S.
Published: April 2023

PDF file, 60K, Effect of dacomitinib on apoptosis in BT-474 and SK-BR-3 parental lines and lines resistant to trastuzumab and lapatinib.
Supplementary Figure 1 from Dacomitinib (PF-00299804), an Irreversible Pan-HER Inhibitor, Inhibits Proliferation of HER2-Amplified Breast Cancer Cell Lines Resistant to Trastuzumab and Lapatinib
Authors: Kalous Ondrej , Conklin Dylan , Desai Amrita J. , O'Brien Neil A. , Ginther Charles , Anderson Lee , Cohen David J. , Britten Carolyn D. , Taylor Ian , Christensen James G. , Slamon Dennis J. , Finn Richard S.
Published: April 2023

PDF file, 60K, Dacomitinib response is associated with relative HER2 mRNA levels.
Supplementary Figure Legend from Attenuation of Argininosuccinate Lyase Inhibits Cancer Growth via Cyclin A2 and Nitric Oxide
Authors: Huang Hau-Lun , Hsu Hui-Ping , Shieh Shu-Chu , Chang Yung-Sheng , Chen Wei-Ching , Cho Chien-Yu , Teng Chiao-Fang , Su Ih-Jen , Hung Wen-Chun , Lai Ming-Derg
Published: April 2023

PDF - 92KB, Supplementary Figure S1,S2,S3 and S4
Supplementary Figure 3 from microRNA-9 Targets Matrix Metalloproteinase 14 to Inhibit Invasion, Metastasis, and Angiogenesis of Neuroblastoma Cells
Authors: Zhang Huanyu , Qi Meng , Li Shiwang , Qi Teng , Mei Hong , Huang Kai , Zheng Liduan , Tong Qiangsong
Published: April 2023

PDF file, 84KB, Knockdown of miR-9 in NB cells in vitro.
Supplementary Figure 3 from Induction of the Transcriptional Repressor ZBTB4 in Prostate Cancer Cells by Drug-Induced Targeting of MicroRNA-17-92/106b-25 Clusters
Authors: Kim KyoungHyun , Chadalapaka Gayathri , Pathi Satya S. , Jin Un-Ho , Lee Ju-Seog , Park Yun-Yong , Cho Sung-Gook , Chintharlapalli Sudhakar , Safe Stephen
Published: April 2023

PDF file, 204K, Effects of proteasome and ROS inhibitors.
Supplementary Table S2 from miRNA-100 Inhibits Human Bladder Urothelial Carcinogenesis by Directly Targeting mTOR
Authors: Xu Chuanliang , Zeng Qinsong , Xu Weidong , Jiao Li , Chen Yanqiong , Zhang Zhensheng , Wu Chengyao , Jin Taile , Pan Anyin , Wei Rongchao , Yang Bo , Sun Yinghao
Published: April 2023

PDF file - 101KB, Primers
Supplementary Figure 3 from Quantitative Proteomic Profiling Identifies Protein Correlates to EGFR Kinase Inhibition
Authors: Kani Kian , Faca Vitor M. , Hughes Lindsey D. , Zhang Wenxuan , Fang Qiaojun , Shahbaba Babak , Luethy Roland , Erde Jonathan , Schmidt Joanna , Pitteri Sharon J. , Zhang Qing , Katz Jonathan E. , Gross Mitchell E. , Plevritis Sylvia K. , McIntosh Martin W. , Jain Anjali , Hanash Samir , Agus David B. , Mallick Parag
Published: April 2023

PDF file, 299KB, Protein level changes associated with gefitinib treatment in NSCLC tissue.
Supplementary Table 1 from PRIMA-1Met/APR-246 Displays High Antitumor Activity in Multiple Myeloma By Induction of p73 and Noxa
Authors: Saha Manujendra N. , Jiang Hua , Yang Yijun , Reece Donna , Chang Hong
Published: April 2023

PDF - 111KB, Supplementary Table 1. Differential expression of genes in U266 cells treated with PRIMA-1Met.