bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Characterization of Three D‐Aspartate Oxidases and One D‐Amino Acid Oxidase from Caenorhabditis elegans
Authors: Katane Masumi , Saitoh Yasuaki , Seida Yousuke , Sekine Masae , Furuchi Takemitsu , Homma Hiroshi
Published: June 2010

Previously, we cloned cDNAs for four Caenorhabditis elegans genes (F20 Hp, C47Ap, F18Ep, and Y69Ap genes) that were annotated in the database as encoding D‐amino acid oxidase (DAO) or D‐aspartate oxidase (DDO) proteins. These genes were expressed in Escherichia coli, and the recombinant C47Ap and F18Ep were shown to have functional DDO activities, while Y69Ap had functional DAO activity. In this study, we improved the E. coli culture conditions for the production of recombinant F20 Hp and, following purification of the protein, revealed that it has functional DDO activity. The kinetic properties of recombinant C47Ap (DDO‐1), F18Ep (DDO‐2), F20 Hp (DDO‐3), and Y69Ap (DAO) were also determined and compared with recombinant human DDO and DAO. In contrast to the low catalytic efficiency of human DDO for D‐Glu, all three C. elegans DDOs showed higher catalytic efficiencies for D‐Glu than D‐Asp or N‐methyl‐D‐Asp. The catalytic efficiency of C. elegans DAO for D‐Ser was substantially lower than that of human DAO, while the C. elegans DAO was more efficient at deamination of basic D‐amino acids (D‐Arg and D‐His) than human DAO. Collectively, our results indicate that C. elegans contains at least three genes that encode functional DDOs, and one gene encoding a functional DAO, and that these enzymes have different and distinctive properties.
Computational Insight into the Mechanism of Serine Residue Racemization
Authors: Takahashi Ohgi , Kobayashi Kana , Oda Akifumi
Published: June 2010

Despite the known racemization of serine (Ser) residues in proteins from aged or diseased human brains, the mechanism of Ser racemization in peptides and proteins has not been studied. This is in contrast to the case of the rapid racemization of aspartic acid (Asp) residues, for which a succinimide‐mediated mechanism is established. In a possible mechanism for Ser racemization, the enolization involving the H(α)‐atom and the CO(α) group occurs by active participation of two H2O molecules. In this study, we computationally modeled this two‐H2O mechanism of enolization for Ser and alanine (Ala) residues using model compounds, and the results were compared with each other and with the case of succinimide analogues reported in a separated paper. Our results suggest that Ser residues are much more racemization‐prone than Ala residues, but to a lesser extent than Asp residues. The side‐chain CO bond of the Ser residue stabilizes the enolization transition state hyperconjugatively.
Aberrant Control of Motoneuronal Excitability in Amyotrophic Lateral Sclerosis: Excitatory Glutamate / D‐Serinevs.Inhibitory Glycine/γ‐Aminobutanoic Acid (GABA)
Authors: Sasabe Jumpei , Aiso Sadakazu
Published: June 2010

The mechanism underlying selective motoneuronal loss in amyotrophic lateral sclerosis (ALS) remains uncertain. The pathogenesis appears to be a complex and multifactorial process. Glutamate excitotoxicity to motoneuron is one of the most intensely investigated targets for the treatment of ALS, and excessive motoneuronal excitation by glutamate through ionotropic glutamate receptors has been mainly demonstrated. However, development of clinically effective drug targeting glutamate is sometimes difficult, because some aspects of glutamergic signals also could be beneficial, as the injured neurons attempt to recruit endogenous recovery. This review is focused on identifying other mechanisms of imbalanced excitation in ALS motoneurons including excitation‐modulatingD‐serine and inhibitory glycine/GABA. Further, validation of these mechanisms might ultimately lead us to new therapeutic targets for ALS.
Accumulation of D‐β‐Aspartic Acid‐Containing Proteins in Age‐Related Ocular Diseases
Authors: Kaji Yuichi , Oshika Tetsuro , Takazawa Yutaka , Fukayama Masashi , Fujii Noriko
Published: June 2010

Transparency is essential for eyes, which serve as cameras. However, decreased transparency caused by accumulation of abnormal proteins is commonly observed especially in elderly people. However, the mechanism of accumulation of abnormal proteins in various ocular diseases is still unclear. In the present study, we investigated the role of D‐amino acids in the development of accumulation of abnormal proteins in age‐related ocular diseases.

Whole eyes with age‐related macular degeneration were excised from four patients. Surgical specimens with pinguecula were excised from eight patients, and specimens with climatic droplet keratopathy were excised from three patients. Polyclonal antibody to the D‐β‐Asp‐containing peptide was prepared. Using the antibody, immunohistochemical localization of D‐β‐Asp‐containing proteins was determined.

In eyes with age‐related macular degeneration, accumulation of abnormal proteins was observed between the retinal pigment epithelial cells and Bruch's membrane. The accumulated abnormal proteins were positive for D‐β‐Asp‐containing peptides. In surgical specimens with pinguecula and climatic droplet keratopathy, abnormal accumulation of proteins seen in the superficial layer of the stroma was positive for D‐β‐Asp‐containing peptide.

The results indicate that development of D‐β‐Asp‐containing proteins in vivo have a central role in the development of accumulation of abnormal proteins in age‐related macular degeneration, pinguecula, and climatic drop‐like dystrophy.
Quantification of Structural Alterations of L‐Asp and L‐Asn Residues in Peptides Related to Neuronal Diseases by Reversed‐Phase High‐Performance Liquid Chromatography
Authors: Sadakane Yutaka , Konoha Keiko , Kawahara Masahiro , Nakagomi Kazuya
Published: June 2010

A method for analyzing the structural alterations in Asn or Asp residues was developed by using the peptides related to neuronal conformational diseases, i.e., the prion protein (PrP)106–126 and the Alzheimer's amyloid β (Aβ) protein6–28. The alterations were analyzed by reversed‐phase (RP) HPLC, because the peptides containing the structurally altered residues were diastereoisomers of each other, and they were separated with the mobile phase containing an MeCN/sodium phosphate solution and NaCl. The amount of L‐Asp, L‐isoAsp, D‐Asp, or D‐isoAsp residues in each PrP peptide isomer was simultaneously quantified by carrying out single HPLC analysis; these residues were generated by the deamidation of the Asn residue. Only 0.3% of the newly generated peptide containing the D‐Asp residue was detected. Furthermore, the investigation of the partial fragment of the Aβ protein revealed that the present method possessed the ability of simultaneous analysis of the isomerizations of two Asp residues. These results implied that the present method was highly sensitive and reduced the time required for the analysis. This method may accelerate the elucidation of the PrP and Aβ protein functions, because the structural alterations of Asn and Asp have been reported to influence these functions.
Effects of D‐Aspartate Treatment on D‐Aspartate Oxidase, Superoxide Dismutase, and Caspase 3 Activities in Frog (Rana esculenta) Tissues
Authors: Burrone Lavinia , Di Giovanni Marcello , Di Fiore M. Maddalena , Chieffi Baccari Gabriella , Santillo Alessandra
Published: June 2010

Although D‐aspartate (D‐Asp) has been recognized to have a physiological role within different organs, high concentrations could elicit detrimental effects on those same organs. In this study, we examined the D‐aspartate oxidase (D‐AspO) activity and the expression of superoxide dismutase 1 (SOD1) and caspase 3 in different tissues of the frog Rana esculenta after chronic D‐Asp treatment. Our in vivo experiments, consisting of intraperitoneal (ip) injections of D‐Asp (2.0 μmol/g b.w.) in frogs for ten consecutive days, revealed that all examined tissues can take up and accumulate D‐Asp. Further, in D‐Asp treated frogs, i) the D‐AspO activity significantly increased in all tissues (kidney, heart, testis, liver, and brain), ii) the SOD1 expression (antioxidant enzyme) significantly increased in the kidney, and iii) the caspase 3 level (indicative of apoptosis) increased in both brain and heart. Particularly, after the D‐Asp treatment we found in both brain and heart (which showed the lowest SOD1 levels) a significant increase of the caspase 3 expression and, vice versa, in the kidney (which showed the highest SOD1 expression) a significant decrease of the caspase 3 expression. Therefore, we speculate that, in frog tissue, D‐AspO plays an essential role in modulating the D‐Asp concentration. In addition, exaggerated D‐Asp concentrations activated SOD1 as cytoprotective mechanism in the kidney, whereas, in the brain and in the heart, where the antioxidant action of SOD1 is limited, caspase 3 was activated.
Collapse of Homochirality of Amino Acids in Proteins from Various Tissues during Aging
Authors: Fujii Noriko , Kaji Yuichi , Fujii Norihiko , Nakamura Tooru , Motoie Ryota , Mori Yuhei , Kinouchi Tadatoshi
Published: June 2010

Prior to the emergence of life, it is believed that only L‐amino acids were selected for formation of proteins, and that D‐amino acids were eliminated on the primitive Earth. Whilst homochirality is essential for life, recently the occurrence of proteins containing D‐β‐aspartyl (Asp) residues from various tissues of elderly subjects has been reported. Here, we discuss the presence of D‐β‐Asp‐containing proteins in the lens, ciliary body, drusen, and sclera of the eye, skin, cardiac muscle, blood vessels of the lung, chief cells of the stomach, longitudinal and circular muscles of the stomach, and small and large intestines. Since the D‐β‐Asp residue occurs through a succinimide intermediate, this isomer may potentially be generated in proteins more easily than initially thought. UV Rays and oxidative stress can accelerate the formation of the D‐β‐Asp residue in proteins.
Thyroid Hormones and D‐Aspartic Acid, D‐Aspartate Oxidase, D‐Aspartate Racemase, H2O2, and ROS in Rats and Mice
Authors: Topo Enza , Fisher George , Sorricelli Andrea , Errico Francesco , Usiello Alessandro , D'Aniello Antimo
Published: June 2010

Total concentrations of thyroid hormones T3 and T4, and of their free forms, FT3 and FT4, D‐aspartic acid (D‐Asp), D‐aspartate oxidase (D‐AspO), D‐aspartate racemase, H2O2, and ROS (reactive oxygen species) were determined in rats and mice. T3 and T4 were 1 and 50 ng/ml, respectively, in serum, and 750 and 40000 ng/g, respectively, in thyroid. Concentrations of the free forms FT3 and FT4 were ca. 250 times lower than their respective total concentrations. The endogenous content of D‐Asp in thyroid gland was ca. 100 nmol/g tissue, whereas the activity of D‐AspO was ca. 80 units/mg thyroid, and that of D‐aspartate racemase was ca. 15 units/mg thyroid. H2O2 Concentration in rat and mouse thyroid gland was ca. 290 pmol/g thyroid, and the concentration of ROS was ca. 10 pmol/DCF/min/mg protein. H2O2 is essential for the iodination of the tyrosyl residues to produce mono‐ and diiodotyrosine that are the precursors for the synthesis of T3 and T4. Production of H2O2 in thyroid glands occurs by oxidation of endogenous D‐Asp by D‐AspO (D‐Asp+O2+H2O→α‐oxaloacetate+NH3+H2O2). D‐Aspartate racemase catalyzes the in vivo production of D‐Asp from L‐Asp. Thus, interaction of endogenous D‐Asp, D‐AspO, and D‐aspartate racemase in thyroid gland constitutes an additional biochemical pathway for the production of H2O2 and consequently for the synthesis of thyroid hormones.
ChemInform Abstract: Evidence for an Isostructural Phase Transition in the Metastable High‐Temperature Modification of TbPdAl.
Authors: Doenni A. , Kitazawa H. , Fischer P. , Fauth F.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Pressure Study of Titanium Carbide.
Authors: Dubrovinskaia N. A. , Dubrovinsky L. S. , Saxena S. K. , Ahuja R. , Johansson B.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Dimeric Ni‐Substituted β‐Keggin Silicotungstate: Structure and Magnetic Properties of K12 [{β‐SiNi2W10O36(OH)2 (H2O)}2]×20H2O.
Authors: Kortz Ulrich , Jeannin Yves P. , Teze Andre , Herve Gilbert , Isber Samih
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Structure of [{Mo(CO)4}2 (cis‐μ‐F2SbF4)3]x [Sb2F11]x: An Ionic Coordination Polymer.
Authors: Broechler Raimund , Freidank Daniel , Bodenbinder Matthias , Sham Iona H. T. , Willner Helge , Rettig Steven J. , Trotter James , Aubke Friedhelm
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An EXAFS Study of AgPO3 and AgBaP3O9.
Authors: Belharouak I. , Fargin E. , Parent C. , Le Flem G. , Aouad H. , Mesnaoui M. , Maazaz M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Room Temperature Sonoelectrochemical Synthesis of Molybdenum Sulfide Fullerene‐Like Nanoparticles.
Authors: Mastai Yitzhak , Homyonfer Moshe , Gedanken Aharon , Hodes Gary
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Photoinduced Intramolecular Arene‐Olefin meta‐Cycloaddition of 5‐Phenyl‐fluorinated‐pent‐1‐enes.
Authors: Guo Xiao‐Chuan , Chen Qing‐Yun
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reduction of Aromatic Azo‐, Azoxy‐, and Nitrocompounds by Ultrasonically Activated Nickel.
Authors: Wang Xiaolun , Xu Minghua , Lian Hongzhen , Pan Yi , Shi Yaozeng
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of Fluorinated Vinamidinium Salts: Novel Reactions of β‐Trifluoromethyl Vinamidinium Salt with Grignard Reagents.
Authors: Yamanaka Hiroki , Uegaki Tomonori , Ishihara Takashi , Kubota Toshio , Gupton John T.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Pot Deprotective Oxidation of O‐Allyl Ethers Using 70% tert‐Butyl Hydroperoxide and Catalytic CrO3.
Authors: Chandrasekhar S. , Mohanty Pradyumna K. , Ramachander T.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation and Functionalization of an Alkenylcopper Reagent Formed by the syn Addition of (Dialkoxyphosphinyl)difluoromethylcopper to Hexafluoro‐2‐butyne.
Authors: Guneratne Ranil D. , Burton Donald J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Stacked ′Push—Pull′ Acetylenes.
Authors: Berger Daniel , Wilhelm Patrick , Neuenschwander Markus
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Synthesis of trans‐Enynes from Substituted Tetrahydropyrans.
Authors: Karadogan Burhan , Edwards Neil , Parsons Philip J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Candida rugosa Lipase as an Enantioselective Catalyst in the Esterification of Methyl Branched Carboxylic Acids: Resolution of rac‐3,7‐Dimethyl‐6‐octenoid Acid (Citronellic Acid).
Authors: Nguyen Ba‐Vu Nguyen Ba‐Vu , Hedenstroem Erik
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Environment Friendly Regiospecific Bromination of Aromatic Ethers by N‐Bromosuccinimide in Presence of Montmorillonite.
Authors: Perumal S. , Vijayabaskar V. , Gomathi V. , Selvaraj S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cationic Complexes with Chiral Diamine or Dithiourea Ligands as Catalysts for Molecular Asymmetric Hydrogenation.
Authors: Tommasino M. Lorraine , Thomazeau Cecile , Touchard Francois , Lemaire M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile and Effective Synthesis of N‐Aryl‐2‐furancarboxamide Derivatives under the Condition of Phase Transfer Catalysis.
Authors: Wei Tai‐Bao , Zhang You‐Ming
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cycloaddition—Rearrangement Sequence of 2‐Amido Substituted Furans as a Method of Synthesizing Hexahydroindolinones.
Authors: Padwa Albert , Brodney Michael A. , Satake Kyosuke , Straub Christopher S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Optically Active Antifungal Azoles. Part 9. An Alternative Synthetic Route for 2‐[(1R,2R)‐2‐(2,4‐Difluorophenyl)‐2‐hydroxy‐1‐methyl‐3‐ (1H‐1,2,4‐triazol‐1‐yl)propyl]‐4‐ [4‐(2,2,3,3‐tetrafluoropropoxy)phenyl]‐3(2H,4H)‐1,2,4‐triazolone and Its Analogues.
Authors: Kitazaki Tomoyuki , Tasaka Akihiro , Hosono Hiroshi , Matsushita Yoshihiro , Itoh Katsumi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chalcogenopyranones from Disodium Chalcogenide Additions to 1,4‐Pentadiyn‐3‐ones. The Role of Enol Ethers as Intermediates.
Authors: Leonard Kristi , Nelen Marina , Raghu Madhavi , Detty Michael R.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of a New Muscarinic M3 Receptor Antagonist, J‐104129.
Authors: Mitsuya Morihiro , Kawakami Kumiko , Ogino Yoshio , Miura Keiko , Mase Toshiaki
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Evaluation of 1,4,5,6‐Tetrahydropyridazine Derivatives as Influenza Neuraminidase Inhibitors.
Authors: Zhang Lijun , Williams Matthew A. , Mendel Dirk B. , Escarpe Paul A. , Chen Xiaowu , Wang Ke‐Yu , Graves Bradford J. , Lawton Geoff , Kim Choung U.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Reactions of Fluoroaryl Substituted 2‐Amino‐3‐cyanopyrroles and Pyrrolo[2,3‐d]pyrimidines.
Authors: Dave Chaitanya G. , Desai Nirmal D.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Pyrido[4,3,2‐de]quinazolines via Nitro‐Substituted Tetrahydroquinolines.
Authors: Katritzky Alan R. , Strah Sonja , Tymoshenko Dmytro O. , Johnson Graham
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: N2‐Acetyl‐O6‐(2‐(P‐nitrophenyl)ethyl)guanine: A Convenient Building Block for the Synthesis of 9‐Substituted Guanine Derivatives.
Authors: Zhou Jinglan , Tsai Jui‐Yi , Bouhadir Kamal , Shevlin Philip B.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthesis of 6‐Aryl‐2,4‐dioxoperhydro‐1,3,5‐triazines.
Authors: Munawar Munawar Ali , Chaudhary Azhar Masud , Athar Makshoof , Siddiq Muhammad , Rauf Abdul
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 4,10‐Dihydro‐5H‐thieno[3,2‐c][1]benzazepine Derivatives and 9,10‐Dihydro‐4H‐thieno[2,3‐c][1]benzazepine Derivatives as Orally Active Arginine Vasopressin Receptor Antagonists.
Authors: Aranapakam Venkatesan , Albright J. Donald , Grosu George T. , Chan Peter S. , Coupet Joseph , Saunders Trina , Ru Xun , Mazandarani H.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 5‐Fluoro‐2‐methyl‐N‐[5‐(5H‐pyrrolo[2,1‐c][1,4]benzodiazepine‐10(11H)‐yl carbonyl)‐2‐pyridinyl]benzamide (CL‐385004) and Analogues as Orally Active Arginine Vasopressin Receptor Antagonists.
Authors: Aranapakam Venkatesan , Albright J. Donald , Grosu George T. , Delos Santos Efren G. , Chan Peter S. , Coupet Joseph , Ru Xun , Saunders Trina , Mazandarani H.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Selective Three‐Component Coupling of Ethyl Propiolate, Alkenes, and Diphenyl Diselenide under Visible‐Light Irradiation.
Authors: Ogawa Akiya , Doi Mikio , Ogawa Ikuko , Hirao Toshikazu
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Structure—Activity Relationships of New Nonsteroidal Progesterone Receptor Ligands.
Authors: Kurihara Ken‐ichi , Tanabe Kiyoshi , Yamamoto Yasuo , Shinei Rie , Ajito Keiichi , Okonogi Tsuneo
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Neovibsanin C, a Macrocyclic Peroxide‐Containing Neovibsane‐Type Diterpene from Viburnum awabuki.
Authors: Kubo Miwa , Minami Hiroyuki , Hayashi Eriko , Kodama Mitsuaki , Kawazu Kazuyoshi , Fukuyama Yoshiyasu
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Approach to the Synthesis of the 17β‐Butenolide Fragment of Cardenolides.
Authors: Paryzek Zdzislaw , Blaszczyk Krzysztof
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantiomerically Enriched (R)‐ and (S)‐α‐Methylphenylalanine via Asymmetric PTC C‐Alkylation Catalyzed by NOBIN.
Authors: Belokon Yuri N. , Kochetkov Konstantin A. , Churkina Tatiana D. , Ikonnikov Nikolai S. , Vyskocil Stepan , Kagan Henri B.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Asymmetric Synthesis of Doubly Branched Carba‐hexopyranoses and Amino Derivatives Starting from the Diels—Alder Adducts of Maleic Anhydride to Furfuryl Esters.
Authors: Jotterand Nathalie , Vogel Pierre , Schenk Kurt
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 3‐Azidotetrahydrofuran‐2‐carboxylates: Monomers for Five‐Ring Templated α‐Amino Acid Foldamers?
Authors: Watterson Mark P. , Pickering Lea , Smith Martin D. , Hudson Sarah J. , Marsh Paul R. , Mordaunt Jacqueline E. , Watkin David J. , Newman Christopher J. , Fleet George W. J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Macrocyclic Spermine Alkaloids from Verbascum: The (E/Z)‐Isomeric Pairs (‐)‐(S)‐Verbasitrine (Ib)/(‐)‐(S)‐Isoverbasitrine (IIb) and (+)‐(S)‐Verbametrine (Id)/(+)‐(S)‐Isoverbametrine (IId): Isolation, Structure Elucidation, and Synthesis.
Authors: Drandarov Konstantin , Guggisberg Armin , Hesse Manfred
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Strategies for Chemical Synthesis of Phosphorodithioates Derived from 2′‐ or 3′‐ or 5′‐Thionucleosides
Authors: Tworowska Izabela , Dabkowski Wojciech
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Artificially Bent Oligonucleotides by Incorporation of Conformationally Rigid 5′‐Cyclouridylic Acid Derivatives
Authors: Sekine Mitsuo , Kurasawa Osamu , Seio Kohji , Shohda Koh‐ichiroh , Wada Takeshi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Deoxyribonucleoside Phosphorodithioate Dimers by a Triester Method
Authors: Capaldi Daniel C. , Cole Douglas L. , Ravikumar Vasulinga T.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The 9‐Fluorenylmethoxycarbonyl (Fmoc) Group and Its Use in Oligonucleotide Synthesis
Authors: Schirmeister‐Tichy H. , Alvardo G. G. , Pfleiderer W.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Biotin Phosphoramidite Reagent for the Automated Synthesis of 5′‐Biotinylated Oligonucleotides
Authors: Zhao Zhengyun , Ackroyd John
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemoselective Synthesis of Dithymidine Phosphorothioate in Solution Using O‐Protected Thiophosphate Monomers
Authors: Boesen Thomas , Kehler Jan , Dahl Otto
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Mild Method for the Preparation of Nucleoside Phosphorofluoridate and Phosphorofluoridothioate Diesters
Authors: Bollmark Martin , Stawinski Jacek
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Methods for Multiple Modifications of a Phosphorus Center. Their Relevance to Nucleotide and Oligonucleotide Analogues Synthesis
Authors: Kers Inger , Cieslak Jacek , Jankowska Jadwiga , Kraszewski Adam , Stawinski Jacek
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Phosphitylating Reagents Containing P—F Bond and Their Application in the Synthesis of P—Fluoro Nucleosidyl Phosphates, Thiophosphates and Selenophosphates
Authors: Dabkowski W. , Tworowska I. , Poniatowska E. , Michalski J. , Cramer F.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective 5′‐Monodeuterated Ribonucleoside Phosphoramidites as Tools for Conformational Studies of RNA by the NMR Approach
Authors: Lukin M. A. , Bushuev V. N.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Chemical Synthesis of Oligonucleotides Containing the 2‐Deoxyribonolactone Site
Authors: Kotera Mitsuharu , Bourdat Anne‐Gaelle , Defrancq Eric , Jourdan Muriel , Garcia Julian , Coulombeau Christian , Lhomme Jean
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 5‐Deazaflavins: New Very Efficient DNA Photosensitizers, Synthesis of Oligonucleotide Conjugates
Authors: Girault I. , Ravanat J.‐L. , Frier C. , Fontecave M. , Cadet J. , Decour J.‐L.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pyranosyl‐oligonucleotides
Authors: Eschenmoser A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Determination of the Absolute Configurations of Norte′s Obtusenynes by Total Syntheses of (12R,13R)‐(‐)‐ and (12S,13R)‐(+)‐Obtusenynes.
Authors: Awakura Daisuke , Fujiwara Kenshu , Murai Akio
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Constituents of Plumbago indica Roots and Reactions of Plumbagin: Part 2.
Authors: Dinda B. , Das S. K. , Hajra A. K. , Bhattacharya A. , De K. , Chel G. , Achari B.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intramolecular Diels—Alder Reactions. Part 4. Formal Total Synthesis of (+)‐Dihydromevinolin via a Chelate‐Controlled Intramolecular Diels—Alder Reaction as the Key Step.
Authors: Schnaubelt Juergen , Frey Barbara , Reissig Hans‐Ulrich
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Replacement of the Quinoline System in 2‐Phenyl‐4‐quinolinecarboxamide NK‐3 Receptor Antagonists.
Authors: Giardina G. A. M. , et al. et al.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Step Solid‐State Reactions at Ambient Temperature — A Novel Approach to Nanocrystal Synthesis.
Authors: Ye Xiang R. , Jia Dian Z. , Yu Jian Q. , Xin Xin Q. , Xue Ziling
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances in Liquid‐Phase Organic Reactions Using Heteropoly Acids and Clays
Authors: Izumi Y. , Urabe K. , Onaka M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Making Drugs out of Oligonucleotides: A Brief Review and Perspective
Authors: Cook P. Dan
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Serine Derivatives in Organic Synthesis
Authors: Kulkarni Yashwant S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Modifications of Ergot Alkaloids
Authors: Bulej Petr , Cvak Ladislav
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Manufacturing Synthesis of an Optically Pure Benzodiazepine (LY300164)
Authors: Anderson Benjamin A. , Vicenzi Jeffrey T. , Zmijewski Milton J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cascade Syntheses with Cumulated Phosphorus Ylides. An Easy Entry to Highly Functionalized N‐, O‐, and S‐Heterocycles
Authors: Loffler Jonas , Schobert Rainer
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multichannel Radical—Radical Reactions
Authors: Polling Michael J. , Stocker David W.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Extreme Conditions Generated by Ultrasounds: Their Use in Industrial Processes
Authors: Gonze E. , Renaudin V.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: β‐K4La6I14Os: A New Structure Type for Rare‐Earth‐Metal Cluster Compounds That Contains Discrete Tetrahedral K4I3+ Units.
Authors: Uma S. , Corbett John D.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alkali Cation Diffusion in the Channel System of Hexagonal Nepheline (K,Na,)Na3[Al3(Al,Si)Si4O16].
Authors: Jimenez Ricardo , Gregorkiewitz Miguel
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Photoelectron Study of Electrochemically Oxidized Nickel and Water Adsorption on Defined NiO Surface Layers.
Authors: Schulze M. , Reissner R. , Lorenz M. , Radke U. , Schnurnberger W.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Molecular and Electronic Structure of Several Heterofullerene BNC58 and B2N2C56 Oligomers and [B2N2C56]n Macromolecule.
Authors: Gal'pern E. G. , Stankevich I. V. , Chistyakov A. L. , Chernozatonskii L. A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Baker′s Yeast‐Induced Asymmetric Reduction of α‐Ketosulfides: Synthesis of Optically Active 1‐(Benzothiazol‐2‐ylsulfanyl)‐2‐alkanols, 2‐Alkanols, and Thiiranes.
Authors: Di Nunno Leonardo , Franchini Carlo , Nacci Angelo , Scilimati Antonio , Sinicropi Maria Stefania
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxidation of Olefins and Hydrazones by Anodically in situ Generated Manganese(III) Acetate.
Authors: Dubey Shipra , Singh Dan , Misra R. A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Remarkably Fast Acylation of Alcohols with Benzoyl Chloride Promoted by TMEDA.
Authors: Sano Tomohumi , Ohashi Kousaburo , Oriyama Takeshi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.