bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of the COVID-19 lockdown on diabetes mellitus, hypertension, and dyslipidemia control in patients in KSUMC, Riyadh
Authors: Al-Shammari Sulaiman , Asiri Faisal , Alanazi Ziad , Alkhaldi Adnan , AlMutairi Abdul , Alangari Abdulaziz , Alharbi Abdulkarim
Published: October 2022

Background: Previous studies on the COVID-19 lockdown reported contradictory evidence on controlling diabetes, hypertension (HT), and dyslipidemia (DLD). Thus, this study aimed to determine pre- and post-lockdown diabetes, HT, and DLD control with patient characteristics and predict positive or negative lockdown changes.
Methods: Three hundred and fifty-five randomly selected patients from King Saud University Medical City (KSUMC) in Riyadh were studied between January 2019 and February 2020 using electronic medical records and phone calls to collect the data. Demographic, biomedical, medication, admission, blood glucose measurement, emergency room visits, and lifestyle data were collected.
Results: The mean body mass index was increased in all demographic variables, particularly in people below the age of 60, and also in males and females (0.054 and 0.172, respectively) after the lockdown. All demographic variables showed a decrease in mean hemoglobin A1c difference. The mean systolic blood pressure difference between patients below the age of 60 and above the age of 60 was 2.00 (0.5491) and 4.54 (1.0812), respectively. 86.5% of the patients accounted for compliance with medications. In addition, 21.40% of the patients exercised regularly, and 36.60% did not follow a diet.
Conclusion: Minor lab changes indicated stable conditions during the lockdown. KSUMC's telemedicine and virtual clinics contributed to this stability. The Ministry of Health's free online consultations were also helpful. A blended clinic (physical and virtual) seemed effective, especially during the pandemic.
Extending The Theory of Reasoned Action (TRA) Model to Predict Consumers’ Intention to Purchase Green Cosmetics
Authors: Wilson Nicholas , Edelyn
Published: October 2022

This research was conducted to further understand several factors which could strengthen consumers’ intention to buy green products which were comprised of attitude, subjective norms, and perceived price. Using the convenience sampling technique, a total of 669 respondents from the Jabodetabek area who’ve purchased any kinds of green cosmetics products at least once for the past 2 years participated in this study. Due to invalid data, 37 data were omitted, thus confirming that 632 data were usable to be analyzed in this research. Implementing the PLS method to analyze the data, the researchers concluded that attitude, subjective norms, and perceived price significantly affect consumers’ intention to buy green cosmetics.
Penelitian ini dilakukan dengan tujuan untuk mengkaji berbagai faktor yang mampu memengaruhi terbentuknya intensi konsumen di dalam membeli produk-produk ramah lingkungan, yang dimana faktor-faktor ini terdiri dari attitude, subjective norms, dan perceived price. Menggunakan teknik convenience sampling, sebanyak 669 responden yang merupakan konsumen yang berasal dari Jabodetabek yang pernah membeli produk kosmetik ramah lingkungan minimal 1 kali dalam kurun waktu 2 tahun terakhir berpartisipasi pada studi ini, yang dimana sebanyak 37 data harus dibuang dikarenakan oleh pengisian data yang tidak lengkap. Alhasil, sebanyak 632 data yang valid selanjutnya dianalisis secara lebih lanjut dengan menggunakan metode PLS. Berdasarkan hasil pengolahan data yang dilakukan, peneliti menyimpulkan bahwa attitude, subjective norms, dan perceived price secara signifikan memengaruhi intensi konsumen di dalam membeli produk kosmetik ramah lingkungan.
Physical Properties Evaluation of Rice Bran Forgery with Corn Cob Addition
Authors: Muhammad Ridla , Martin Rima , Nahrowi Nahrowi , Alhasanah Nahdhiyah , Fadhilah Markistiandi
Published: October 2022

The objective of this study was to evaluate physical properties of rice bran forgery with corn cob addition. Corn cob mixed with rice bran by different levels 0%, 5%, 10%, 15%, and 20%. The experimental design was completely random design (CRD) with 5 treatments and 3 replications. The data were analyzed by ANOVA and followed by orthogonal contrast test if there were significant differences between the treatments. The results showed the addition of corn cob (0%, 5%, 10%, 15% and 20%) significantly (P<0.01) decreased the specific gravity (kg L-1) by 1.36, 1.32, 1.26, 1.20 and 1.16 (r = 93%), bulk density (g L-1) by 286.53, 283.02, 275.74, 268.35 and 263.86 (r = 98%), compact bulk density (g L-1) by 475.44, 463.69, 453.18, 443.14 and 433.53 (r = 99%) and angle of repose (˚) by 44.40, 43.91, 43.27, 43.15 and 42.70 (r = 93%) while the particle size (mm) increased by 1.22, 1.23, 1.23, 1.24 and 1.25 (r = 95.8%). Detection of rice bran forgery can be evaluated through physical test correlation and the highest correlation is found in the compact bulk density parameter.
PERLINDUNGAN HUKUM TERHADAP PEMEGANG HAK MEREK TERKENAL HUGO BOSS DARI PENIRUAN
Authors: Ida Ayu Ketut Artami  , Kadek Januarsa Adi Sudharma  , Made Widya Prasasti
Published: October 2022

Demi meningkatkan prestige, masyarakat Indonesia lebih memilih untuk membeli produk merek terkenal. Hal itu kemudian dimanfaatkan oleh pengusaha untuk memperoleh keuntungan dengan melakukan pelanggaran merek terhadap merek internasional terkenal. Salah satu merek yang kerap ditiru ialah HUGO BOSS yang terkenal dibidang fashion. Rumusan masalah yang timbul dari latar belakang tersebut ialah bagaimana prosedur pendaftaran merek internasional di Indonesia? ; bagaimana perlindungan hukum terhadap pemegang hak merek HUGO BOSS di Indonesia menurut UU No. 20 T ahun 2016 (UU MIG)?. Penelitian hukum normatif dipakai dalam penelitian ini. Jenis bahan hukum yang dipergunakan adalah bahan hukum primer yaitu UU MIG, sekunder berupa literatur, dan tersier berupa kamus. Penulis menggunakan pendekatan kasus dan perundang-undangan. Pengumpulan bahan hukum dikerjakan dengan menginventarisasi sumber hukum positif. T eknik deskriptif kualitatif digunakan dengan menggambarkan suatu kebijakan terkait dengan hak merek dengan perlindungan hukum yang mengkhusus kepada merek terkenal secara sistematis. Hasil dari penelitian ini adalah Prosedur pendaftaran merek internasional di Indonesia dilakukan berdasarkan UU MIG Pasal 52 yang diatur lebih lanjut dalam PP Protokol Madrid. Pihak yang berasal dari luar negeri jika ingin mendaftarkan mereknya di Indonesia harus terlebih dahulu menyerahkan permohonan pendaftaran mereknya kepada biro internasional yang kemudian akan diteruskan kepada Menteri. Perlindungan hukum yang diberikan terhadap pemegang hak merek terkenal HUGO BOSS adalah perlindungan hukum secara preventif yaitu dengan melakukan pendaftaran merek agar mendapat perlindungan hukum sesuai peraturan yang berlaku. HUGO BOSS juga mendapatkan perlindungan hukum secara represif yaitu dengan mengajukan gugatan pembatalan merek ke Pengadilan Niaga serta mengajukan kasasi kepada MA.
How do developed countries motivate volunteering: Comparative analysis of National Recognition Awards for volunteer in the United Kingdom, United States, Canada, and Ireland
Authors:   School of Management, Minzu University of China, Beijing 100081, China, Tong Yulin , Li Jian ,   School of Management, Minzu University of China, Beijing 100081, China
Published: October 2022

Purpose: With the rapid growth of volunteering in worldwide, the question of how to recognize volunteers at the national level to motivate volunteering has become a pressing matter. In a few of developed nations, volunteering is motivated by the establishment of national recognition awards for volunteer. As a result, the goal of this paper is to aid decision-makers in enhancing volunteering by drawing on the experience of these developed countries. Methods: This paper adopts a literature-based approach and presents a comparative analysis of national recognition awards for volunteer in the United Kingdom, the United States of America, Canada, and Ireland. The comparison factors include the objectives of awards, categorization criteria, eligibility prerequisites, nomination requirements, and the evaluation process. Following that, an examination of similarities and differences between the awards will be presented, and the article will end with some suggestions. Results: Each of these four countries has established standardized and effective criteria for volunteers’ recognition awards, despite that each country's practices vary to some extent. Based on these circumstances, nations conscious of the importance of volunteer recognition which should expedite the establishment of national recognition awards for volunteers, broaden participation, focus on the effectiveness of service, establish reasonable application standards while ensuring the transparency of the selection process, and actively seek to expand cooperation with other social organizations.
On the Strengthening of the Chthonic Principle in the Revived Aphrodite Cult in the Northern Black Sea Region in the First Centuries a.d.
Authors: Yartsev Sergey  Vladimirovich , Shushunova Elena  Valeryevna
Published: October 2022

The research object is the domain of Hellenic religious worldview in the Northern Black Sea region during the Antiquity era. The research focuses on the revival of the Aphrodite cult in the Bosporus and Chersonese in the first centuries A.D. and the strengthening of the chthonic element in these beliefs. The authors consider in detail such aspects of the topic as the mythological origin, the presence of various epicleses of the Greco-barbarian Aphrodite, her connection with other female deities, as well as the features of the chthonic functions originally inherent in this goddess of love and family life. The article pays particular attention to Aphrodite's involvement in funerary rites and the deity's patronage of dead souls. The main research conclusions stem from the identified multifactorial reasons for the popularity of the Aphrodite cult in the Northern Black Sea region in the Roman period. The most important of these are the distribution of the deity's cult among the Romans and the possibility of Aphrodite's divine protection covering a wide enough range of the local population, including sailors, as well as the peculiarities of the reaction of local Hellenes to the Roman cultural expansion. The authors' special contribution to the study of the subject is to link the radical changes in the veneration of Aphrodite in the Northern Black Sea region with the democratization of the apotheosis of the dead in the first centuries A.D. The novelty of the research lies in conducting the first comprehensive study in historiography on this topic, which has revealed one of the main reasons for the return of popularity, as well as the archaization of the Aphrodite cult in the Northern Black Sea region during the Roman period. According to the authors, it was an increased need for the deification of deceased relatives, in order to ensure the peace of their souls and achieve immortality. It was Aphrodite, the oldest and supreme Hellenic deity as Mistress of the afterworld, who could most effectively breathe divine powers into the deceased as well as ensure that he/she would be born in a new capacity.
Modeling and Characterizing Aircraft Trajectories Near Airports Using Extracted Control Actions
Authors: Chakrabarti Sharmistha , Vela Adan E.
Published: October 2022

With the long-term goal of supporting the training of air traffic controllers and ensuring safety through real-time monitoring of operations, we propose a clustering-based framework that seeks to extract, model, and characterize the control actions of air traffic controllers when managing aircraft within the immediate vicinity of an airport. Toward achieving our goal, we begin by developing and applying a hidden Markov model to identify and extract heading changes within aircraft trajectories. Identification of these heading changes allows for translating spatially defined trajectories into variable-length strings describing executed lateral maneuvers resulting from the control actions of air traffic controllers. The trajectory strings are then compared and clustered using edit-distance metrics in combination with the [Formula: see text]-medoids clustering algorithm. Taken together, each step forms a consistent framework for modeling and understanding trajectories in the context of control actions of air traffic controllers. The proposed modeling and clustering framework also enables identification of anomalous and potentially disruptive decisions when managing aircraft. Through application on a set of historical trajectories at Washington National Airport, we are able to demonstrate that the proposed framework is able to successfully overcome shortfalls associated with traditional clustering techniques.
Basilisk-Based Benchmark Analysis of Different Constrained Attitude Dynamics Planners
Authors: Calaon Riccardo , Schaub Hanspeter , Trowbridge Michael A.
Published: October 2022

Maneuvering a spacecraft subject to rotational constraints is a nontrivial challenge. Several attitude guidance solutions are found in literature that use a range of approaches to provide guidance algorithms to safely reorient a spacecraft while ensuring that all constraints and requirements are satisfied. However, such algorithms are often problem specific, and/or not immediately comparable with one another as they have slightly different objectives. The purpose of this paper is to show how a range of constrained attitude guidance solutions can be compared using the open-source Basilisk Astrodynamics Simulation Framework. New Basilisk modules are introduced to allow users to easily set up a customizable simulation environment that can be used as a benchmarking tool to test the performances of different guidance algorithms. The simulation allows for guidance solutions to be implemented within Basilisk or read in from a file generated by an outside attitude path planner. Sample performance metrics are defined and implemented within a Basilisk module to illustrate this approach performing a numerical comparison between the different guidance strategies.
Liturgiczna troska o chorych i cierpiących w wybranych orędziach św. Jana Pawła II na Światowy Dzień Chorego
Authors: Czerwiński Adrian Mateusz
Published: October 2022

Abstrakt
            Artykuł przedstawia nauczanie Jana Pawła II zawarte w orędziach na Światowy Dzień Chorego. Celem publikacji jest wydobycie z wybranych orędzi treści o liturgicznym posługiwaniu chorym i cierpiącym. Drugim celem jest ukazanie przemieniającej łaski Chrystusa w trudnym doświadczeniu choroby, cierpienia, śmierci, w których chory uczestniczy. Nauka ta zapisana i realizowana w liturgii jest skierowana zarówno do wierzących jak i niewierzących. W orędziach możemy odnaleźć kilka płaszczyzn, na których troska o los chorych i cierpiących jest wyrażana w liturgii. Należą do nich: centralne miejsce Mszy świętej w corocznych obchodach Światowego Dnia Chorego, podkreślenie wartości sakramentów: przede wszystkim Eucharystii i pokuty, każdorazowe wspomnienie o maryjnym sanktuarium oraz nakreślenie misji kapłanów pełniących sakramentalną posługę chorych. Papieskie pojmowanie liturgii w orędziach ogniskuje się wokół problemu przyjmowania cierpienia wedle wiary katolickiej wyrażonej w liturgii, świadczenia o autentyczności orędzia Chrystusa w chorobie oraz ewangelizacyjnej i przemieniającej roli liturgii wobec ludzi wierzących i niewierzących. Spojrzenie papieża Jana Pawła II nie ogranicza się tylko do kwestii rytualnych czy dyscyplinarnych, ale kieruje się na dialog między Bogiem, Kościołem, człowiekiem i światem, w którym liturgia ma budować jedność opartą na Chrystusie i prowadzić do moralnego, duchowego a w końcu do eschatologicznego odnowienia człowieka i świata. Rozważania te są bardzo istotne w perspektywie współczesnych zmian dokonujących się w Kościele, odrzucenia przez człowieka współczesnego nauki o krzyżu Chrystusa, którą wierni powinni z mocą Ducha Świętego głosić na nowo, epidemii koronawirusa, który pokazał liczne słabości wspólnoty wierzących
Kobieta w liturgicznym życiu Kościoła
Authors: Sielepin Adelajda
Published: October 2022

Miejsce kobiety w Kościele i w liturgii od wieków nie jest sprawą oczywistą, a ostatnie motu proprio  Spiritus Domini Papieża Franciszka ożywiło dyskusję na ten temat. W niniejszym artykule podejmujemy temat szerzej, zgodnie z faktami historycznymi, które pozwalają mówić o roli kobiety w życiu liturgicznym Kościoła. Celem tego opracowania jest pokazanie specyfiki powołania kobiety, unikając najczęściej spotykanych porównań i oceny kobiety i mężczyzny w obszarach działalności świeckiej i religijnej. Starożytne źródła świeckie i patrystyczne okazują się bardzo silną i wpływową opcją, kształtującą interpretację Ewangelii i Tradycji Kościoła co do rozumienia misji kobiety w liturgii. Wskutek tego misja ta do tej pory jeszcze uwarunkowana jest w znacznej mierze przesłankami kulturowymi i społecznymi, a wciąż otwarty dla adaptacji pozostaje aspekt chrystologiczny i eklezjalny, który ukazuje misję kobiety w wymiarze mistycznym i teologicznym. Soborowe Magisterium Kościoła wprowadza wiele odkrywczych wątków na ten temat, ale jeszcze wciąż nie jest w pełni rozumiane i akceptowane. Kluczem do odczytania miejsca kobiety w liturgii jest poznanie jej relacji do Misterium Chrystusa, którą w pełni odsłania chrystocentryczna mariologia. Tym samym rośnie przekonanie, że  godność kobiety i jej właściwe miejsce w liturgii rozumianej jako Misterium Chrystusa i Kościoła zależy od przejrzystej i jednoznacznie chrystologicznej postawy mężczyzn, a szczególnie duchownych.
Resurrecting the ambo Part 1
Authors: Ryan Fergus Michael Timothy
Published: October 2022

The use of the ambo during the celebration of Mass with a congregation was restored to the Roman rite in 1964, it seemed after centuries of absence. Limited use of the ambo during Mass, or remains of the ambo such as lecterns, had continued interrupted in some Western rite contexts from the Council of Trent until the Second Vatican Council. The reception of the ambo from 1964 was rather modest with respect to its monumental history and symbolic wealth. This was due, no doubt, to the significance and history of the ambo going unnoted in Roman documentation and liturgical books in the years after Sacrosanctum Concilium. Renewed emphasis on the significance of the ambo on the part of the Roman dicastery for divine worship appeared in the context of the Roman rite in the late 1980s and once again in the Jubilee year 2000 but seems to have been overlooked in the vast majority of local churches. The author reviews what he considers to be a gradual restoration of the ambo to its medieval heyday while seeing that same restoration as central in placing the celebration of Christ’s paschal mystery at the heart of the liturgy renewed after Vatican II.
Rhinocerebral Form of Invasive Mycosis in COVID-19 Patients: Clinical Course, Diagnosis, Treatment Experience
Authors: Savosin Yu. V. , Shafranova S. K. , Gaivoronskaya T. V. , Avdeeva M. G. , Vartanyan S. A.
Published: October 2022

Background. The incidence of invasive mycoses is reported to increase among patients with a history of new coronavirus infection COVID-19. Adhesion and damage of endothelial cells by zygomycetes lead to fungus angioinvasion, release of a large number of fungal proteases, lipases and mycotoxins, as well as vascular thrombosis, subsequent necrosis of tissues.

Objectives. Improvement of the diagnosis and treatment for COVID-19 associated invasive mycosis.

Methods. Examination and treatment of 143 patients with invasive mycosis of the maxillofacial area in the period from August 2021 to May 2022 at the Maxillofacial Unit of Regional Clinical Hospital of Emergency Medical Care, Krasnodar Krai, Russia. The diagnosis was confi rmed by cytological, culture-based methods, as well as pathomorphological study of surgical specimen. Follow-up monitoring was carried out in 1, 3, 6 months, with repeated CT and MRI investigations. The group under follow-up monitoring included 91 patients. The incidence of signs was determined via descriptive statistics methods in proportion of the total number of observations and expressed as a percentage. Statistika 12.5 and Excel 2010 (Windows 10) were used in the study, the graphical representation of the material was made in the same programs.

Results. Manifestation of invasive mycoses of the maxillofacial area occurred during the early convalescent period of coronavirus infection in specialized infectious hospitals or within two weeks after discharge from the hospital. A typical clinical picture includes rhinocerebral zygomycosis with the development of fungal osteomyelitis of the upper jaw, nasal bones, zygomatic bone, ethmoidal labyrinth bones, sphenoid bone, frontal bone. 17 cases (11.9%) had a lethal outcome as a result of disseminated form of fungal infection caused by Mucorales (14 patients), Aspergillus (3 patients) with damage to the brain, lungs, kidneys and fatal massive necrotic lesions of the craniofacial area. An integrated approach embraced early antifungal therapy (Amphotericin B) as well as surgical debridement of the lesions and provided a positive effect in treatment.

Conclusion. Invasive fungal infections require prompt diagnosis and early prescription of antifungal therapy (prior to histological confi rmation of diagnosis) to minimize consequences and prevent fatal outcome. Due to the nonspecifi c nature of clinical symptoms and diffi culties of early diagnosis of invasive zygomycosis and aspergillosis, it is necessary to be alert to potential invasive aggressive mycoses in immunocompromised patients who have a history of a new coronavirus infection COVID-19.
Comparative Evaluation of Biomechanical Characteristics of Acellular Dermal Matrix for Hernioplasty
Authors: Melkonian K. I. , Popandopulo K. I. , Bazlov S. B. , Rusinova T. V. , Moskalyuk O. A. , Bykov I. M.
Published: October 2022

Background. With the introduction of synthetic mesh implants into clinical practice, the recurrence rate of postoperative ventral hernias was signifi cantly reduced. The extensive use of synthetic implants led to the development of specifi c complications. The development of biological implants, based on extensively purifi ed decellularized collagen matrix of xenogeneic origin is highly relevant due to the fact that, unlike synthetic analogues, they have a biological origin and biodegrade in a natural way, gradually being replaced with newly formed connective tissue. The use of bioprostheses reduces the risk of complications.

Objectives. To conduct a comparative evaluation of the biomechanical characteristics of acellular dermal matrix, obtained by detergent-enzymatic decellularization, and commercially distributed Permacol™ matrix.

Methods. Acellular dermal matrix (ADM) was created by using samples of native skin of pig of Landras breed aged 4 months. The dermis was processed by means of detergent-enzymatic method. In order to evaluate and compare the mechanical properties of acellular dermal matrix, the biological samples were divided into 2 groups of 15 samples each. The fi rst group included acellular dermal matrix samples, the second group — native samples of pigs unprocessed dermis. The control group consisted of samples of PermacolTM Surgical Implant, xenotransplant for hernioplasty approved for use in the Russian Federation (Covidien, France). All samples were tested wet using universal testing instrument Instron 1122. MedCalc Statistical Software (Belgium) was used for statistical processing of the study results.

Results. In the present study, pig dermis was processed using a detergent-enzymatic method to produce ADM. Routine histological examination confi rmed the removal of all cellular elements, and at the same time it was proven that the native structure of the dermis remained intact during its processing. The mechanical characteristics of xenogenic ADM were further determined. Its tensile strength was 9.1 ± 0.6 MPa (910 N/cm2 ), elongation to break was 21.1 ± 2.3%, and elastic modulus was 50.0 ± 1.6 MPa. These characteristics largely corresponded to the strength characteristics of native pig dermis and far exceeded the necessary physiological parameters. PermacolTM control was tested in two directions (longitudinal and transverse). In the longitudinal direction, the sample had higher mechanical characteristics: strength — 12.0 ± 1.7 MPa, elongation to break — 29.7 ± 2.4%, stiffness modulus — 47.2 ± 6.5 MPa. In the transverse direction, all indicators were 1.5–2 times lower.

Conclusion. The developed xenogeneic biological implant in the form of ADM demonstrates rather good characteristics of plasticity, tensile strength and elasticity, to be used as a biological endoprosthesis for plasty of hernia defects of the abdominal wall of any size and shape.
New findings on fiber intake in children
Authors: Sunardi Diana
Published: October 2022

Fibre is an essential component of the human diet that is crucial for human health, the physiological and functional effects of dietary fibre are associated with a wide range of short-term and long-term health benefits. Fibre provides an energy source for the gut microbiome. The fermentation of fibre by the gut microbiome results in the production of a variety of compounds with short-term and long-term health benefits that extend beyond the gut, to the immune system and organs such as the liver, kidneys and even the brain. The short-term benefits include supporting the immune system, especially within the gut itself, preventing or ameliorating autoimmune diseases such as diabetes, inflammatory arthritis, inflammatory gastrointestinal disorders and allergic disease.
Parenteral multivitamins in hospitalized patients
Authors: Puruhita Niken
Published: October 2022

Malnutrition, especially micronutrient malnutrition remain as major problems in hospitalized patients. Micronutrient malnutrition contributes to health status and recovery speed of patients. It may lead to poor wound healing and/or increasing the risk of complication which result in longer hospital stay or even, death. Critically or acutely ill patients who are in total parenteral nutrition therapy for longer period need intravenous micronutrients. Past publications reported Wernicke’s Beri-beri in patient who did not received vitamins along with total parenteral nutrition infusion after 4 weeks passed away regardless the amounts of macronutrients delivered.
Multi disciplinary approach in weight management: Experience in the Philippines
Authors: Fransisco Eliza Mei
Published: October 2022

Our Weight Management Centers are composed of a multidisciplinary team of medical specialists (Medical Nutrition, Endocrinology, Surgery, Rehab Medicine, Sleep Medicine, Bariatric Surgery) and allied professionals such as clinical dietitians, physical therapists, psychologists, and nurses. The multi-disciplinary and inter-disciplinary approach helps patients embark on lifestyle changes and succeed in overcoming obesity.
Obesity in young adults: The effectiveness of self-empowerment-based patient-centered care in students with obesity in primary services
Authors: Dewi Dian Kusuma
Published: October 2022

The case of obesity in children and adolescents has increased every year globally. In 2016, the BMI of women aged 20 years and over globally reached 24.8 (24.6-25), while that of men reached 24.5 (24.3-24.6).  According to the RISKESDAS, the proportion of obesity measured as central obesity at the age of >15 years in Indonesia increased throughout 2007, 2013 and 2018 by 18.8%, 26.6% and 31%. RISKESDAS 2018 concluded that obesity in adulthood increased in 2013 compared to 2007, the trend of non-communicable diseases (PTM) namely diabetes mellitus and hypertension also increased. The Medical Check-Up which was held to the new students of University of Indonesia in 2017 found that there were 1817 new students that classified as obese from the total 7268 new students (38.6% were obese). 2018, it was found that 24% out of 7487 new students were obese. In 2019, there were 29% out of 8583 new students that classified as obese.
Pemanfaatan Limbah Kulit Buah Nanas (Ananas Comosus L. Merr) Menjadi Sirup Dan Nata de Pina Untuk Meningkatkan Pendapatan Rumah Tangga
Authors: Wahyu Prima , Elfis Elfis , Khairani Khairani , Janna Nadiatul
Published: October 2022

Sampah kulit Nanas (Ananas comosus L. Merr) ini dibiarkan membusuk, sehingga mengeluarkan bau yang kurang sedap, padahal kulit nenas ini masih bisa diolah lebih lanjut menjadi Sirup nenas dan Nata de Pina. Tidak adanya pengolahan lanjutan ini karena penduduk Desa Kualu Nanas, tidak memahami cara mengolah kulit nanas menjadi Sirup nenas dan Nata de Pina. Untuk mengatasi permasalahan tersebut maka ditawarkan solusi sebagai berikut: (1) Memberikan pelatihan dan pendampingan teknis kepada target sasaran dan mitra masyarakat pengolahan sampah kulit nenas untuk diolah menjadi Sirup Nanas dan Nata de Pina, (2) Teknik pembuatan Sirup Nenas dan Nata de Pina diarahkan dalam bentuk industri rumah tangga (home industry) sehingga menghasilkan nilai tambah untuk meningkatkan pendapatan rumah tangga, dan (3) Teknik pembuatan Sirup Nanas dan Nata de Pina menggunakan teknik yang paling sederhana tetapi tetap memenuhi persyaratan  yang diharuskan (kehalalan, kesehatan, estetik, kuliner). Metoda Pelaksanaan menggunakan teknik Pelatihan, praktek, diskusi dan pendampingan. Tolak ukur keberhasilan PkM ini adalah : Target sasaran dan Mitra Masyarakat telah mebuat Sirup Nanas dan Nata de Pina yang  memenuhi persyaratan  yang diharuskan (kehalalan, kesehatan, estetik, kuliner).
Pelatihan Desain LKPD dalam Pembelajaran Matematika Terintegrasi Karakter Positif Bagi Guru-Guru Sekolah Menengah/Madrasah di Pekanbaru
Authors: Herlina Sari , Zetriuslita  , Suripah Suripah , Istikomah Endang , Yolanda Fitriana , Rezeki Sri , Amelia Sindi , Widiati Indah
Published: October 2022

Bagi seorang guru, menciptakan pendidikan karakter pada pembelajaran matematika adalah hal yang esensial. Sehingga, perludiadakan kegiatan kegiatan akademik seperti bimbingan teknis bagi guru-guru SMP/MTS dalam mendesain Lembar Kerja Peserta Didik (LKPD) yang Terintegrasi Nilai-nilai Karakter Positif pada Pembelajaran. Kegiatan ilmiah ini dikemas dalam pengabdian kepada masyarakat yang dilakukan dari aplikasi Zoom dan melalui YouTube Pendidikan Matematika FKIP UIR pada hari Kamis, 3 Desember 2020. Metode dalam pengabdian ini yaitu penyampaian materi tentang cara mendesain LKPD, tanya jawab dan diskusi. Dalam hal ini pemateri membahas hal utama yang harus diperhatikan sebelum membuat LKPD yaitu tujuan dari pendidikan itu sendiri yang memuat muatan karakter didalam mendesain LKPD tersebut. Dengan kegiatan pengabdian ini maka guru-guru dapat mendesain dan membuat LKPD yang dikaitkan dengan pendidikan karakter positif yang diharapkan dapat tertanam dalam diri siswa.
UPAYA DINAS KELAUTAN DAN PERIKANAN DALAM KONSERVASI KELAUTAN DI WILAYAH BINTAN TIMUR
Authors: Fiona dwi yanti
Published: October 2022

The East Bintan area is a conservation area determined by a Ministerial Decree on the grounds that the ecosystem and habitat of the original biota owned by the East Bintan area must be protected.  The role of the Department of Marine Affairs and Fisheries in the preservation of the East Bintan area by making policies in the utilization of natural resource management.  for supervision.  So that the marine ecosystem is not damaged and can be used for welfare, especially for the surrounding community.  The preparation of this scientific article aims to provide information about the efforts of the Department of Marine Affairs and Fisheries in the Conservation of the East Bintan Region.  The preparation of this article was carried out in June 2022 using a qualitative method with descriptive analysis based on the results of a literature study using secondary data as information.  Water Conservation Area in the Eastern Region of Bintan Island, Riau Islands Province with an area of ​​138,561.42 Ha.
EVALUATION OF THE EFFECTIVENESS OF MANAGING THE POTENTIAL OF E-BUSINESS ENTERPRISES
Authors:   Lviv University of Business and Law, Pohrebniak Andrii , Pylypenko Iov ,   Lviv Polytechnic National University, Batkovets Nataliia ,   Lviv Polytechnic National University, Abramowicz Maciej ,   Institute of Labour and Social Studies in Warsaw, Рavlenchyk Anatolii ,   Lviv State University of Physical Culture named after Ivan Boberskyj, Rusyn-Hrynyk Roman ,   Lviv Polytechnic National University
Published: October 2022

Enterprise potential management is an important indicator of the successful activity of the enterprise in the market and gaining competitive advantages over potential competitors. Preserving and increasing the level of enterprise potential should be carried out on the basis of scientific substantiation when using the method of assessing this level. Conducting an effective assessment of e-business enterprise potential management requires a more detailed and objective definition of criteria and management methods. The effectiveness of management decisions is influenced by a number of principles, namely: economic feasibility, informativeness, prospects. It is substantiated that the economic efficiency of managing the potential of an e-business enterprise should be assessed by comparing the indicators of financial and economic activity and the costs associated with the introduction of innovative management solutions. It is proved that the set of methods for assessing the economic potential of an enterprise is divided into two groups: express diagnostics and fundamental diagnostics. More and more managers of e-business enterprises use the method of comparing integral indicators, which is able to reflect the stability of the enterprise under external and internal changes.
Overcoming the Limitations of Kolbe Coupling via Waveform-Controlled Electrosynthesis
Authors: Hioki Yuta , Costantini Matteo , Griffin Jeremy , Harper Kaid , Prado Merini Melania , Nissl Benedikt , Kawamata Yu , Baran Phil
Published: October 2022

The Kolbe reaction has seen limited applications owing to its extremely poor chemoselectivity and reliance on precious metal-based electrodes, despite its potential to be one of the workhorse reactions of organic synthesis for C–C bond formation in both discovery and process settings. Although hundreds of studies over a century aimed to improve its efficiency and selectivity, general solutions have yet to be found. Herein, an exceedingly simple solution to this long-standing challenge is presented by merely tuning the waveform employed. Thus, switching from classic direct current (DC) to rapid alternating polarity (rAP), a broad range of functional groups can now be tolerated using inexpensive and sustainable carbon-based electrodes. A variety of high-value molecules ranging from useful unnatural amino acids to promising polymer building blocks are now accessible from readily available carboxylic acids, including biomass-derived acids. The practicality of the rAP-Kolbe reaction enables facile implementation of large-scale reactions, realizing access to novel degradable polymers from biomass. Preliminary mechanistic studies implicate the role of waveform in modulating the local pH around electrodes, which in turn affects the underlying redox processes. The ease, efficiency, and chemoselectivity of the rAP-Kolbe reaction finally opens the door to the widespread mainstream adoption of this classic reaction.
Atomistic insights into the pre-nucleation phase of Zeolitic Imidazolate Frameworks growth
Authors: Balestra Salvador R G , Martínez-Haya Bruno , Cruz-Hernández Norge , Lewis Dewi W. , Woodley Scott M. , Semino Rocío , Maurin Guillaume , Ruiz-Salvador A. Rabdel , Hamad Said
Published: October 2022

We have studied the clusters involved in the initial stages of nucleation of Zeolitic Imidazolate Frameworks, employing a wide range of computational techniques. In the pre-nucleating solution, the prevalent cluster is the ZnIm4 cluster (formed by a zinc cation, Zn2+ , and four imidazolate anions, Im−), although clusters such as ZnIm3, Zn2Im5, Zn2Im7, Zn3Im9, Zn3Im10, or Zn4Im12 have energies that are not much higher, so they would also be present in solution at appreciable quantities. All these species, except ZnIm3, have a tetrahedrally coordinated Zn2+ cation. Small Znx Imy clusters are less stable than the ZnIm4 cluster. The first cluster that is found to be more stable than ZnIm4 is the Zn41Im88 cluster, which is a disordered cluster with glassy structure. Bulk-like clusters do not begin to be more stable than glassy clusters until much larger sizes, since the larger cluster we have studied (Zn144Im288) is still less stable than the glassy Zn41Im88 cluster, suggesting that Ostwald’s rule (the less stable polymorph crystallizes first) could be fulfilled, not for kinetic, but for thermodynamic reasons. Our results suggest that the first clusters formed in the nucleation process would be glassy clusters, which then undergo transformation to any of the various crystal structures possible, depending on the kinetic routes provided by the synthesis conditions. Our study helps elucidate the way in which the various species present in solution interact, leading to nucleation and crystal growth.
Gold Photocatalysis in Sustainable Hydrogen Peroxide Generation
Authors: Adnan Rohul , A Jalil Aishah
Published: October 2022

Hydrogen peroxide (H2O2) is a mild and green oxidant widely employed in organic syntheses, medical sector, disinfection, pulp bleaching, environmental remediation and biological processes. However, its production via the expensive, multiple steps and energy intensive anthraquinone process renders it less sustainable. Photocatalysis is a viable, sustainable and promising strategy to produce H2O2 from green sources: water and molecular O2. This article presents the key developments of photocatalytic H2O2 production using gold (Au) nanoparticles supported on semiconductor photocatalysts. Several photocatalytic systems containing Au nanoparticles and the roles of Au nanoparticles in enhancing the photocatalytic H2O2 production including increasing the visible light absorption, facilitating the charge carrier separation and transfer, and as a catalytic Au active site are discussed. Factors defining the photocatalytic activity such as the effects of Au particle size and loading, localised surface plasmon resonance, mixed-gold component, and design of photocatalysts are reviewed. Finally, the challenges and prospect for further developments of Au photocatalysis in sustainable H2O2 synthesis as well as other related applications are highlighted.
Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish
Authors: Uszczynska-Ratajczak Barbara , Sugunan Sreedevi , Kwiatkowska Monika , Migdal Maciej , Carbonell-Sala Silvia , Sokol Anna , Winata Cecilia L , Chacinska Agnieszka
Published: October 2022

Most mitochondrial proteins are encoded by nuclear genes, synthetized in the cytosol and targeted into the organelle. To characterize the spatial organization of mitochondrial gene products in zebrafish (Danio rerio), we sequenced RNA from different cellular fractions. Our results confirmed the presence of nuclear-encoded mRNAs in the mitochondrial fraction, which in unperturbed conditions, are mainly transcripts encoding large proteins with specific properties, like transmembrane domains. To further explore the principles of mitochondrial protein compartmentalization in zebrafish, we quantified the transcriptomic changes for each subcellular fraction triggered by thechchd4a−/−mutation, causing the disorders in the mitochondrial protein import. Our results indicate that the proteostatic stress further restricts the population of transcripts on the mitochondrial surface, allowing only the largest and the most evolutionary conserved proteins to be synthetized there. We also show that many nuclear-encoded mitochondrial transcripts translated by the cytosolic ribosomes stay resistant to the global translation shutdown. Thus, vertebrates, in contrast to yeast, are not likely to use localized translation to facilitate synthesis of mitochondrial proteins under proteostatic stress conditions.
Stepwise progression of β-selection during T cell development involves histone deacetylation
Authors: Chann Anchi S , Charnley Mirren , Newton Lucas M , Newbold Andrea , Wiede Florian , Tiganis Tony , Humbert Patrick O , Johnstone Ricky W , Russell Sarah M
Published: October 2022

During T cell development, the first step in creating a unique T cell receptor (TCR) is genetic recombination of the TCRβ chain. The quality of the new TCRβ is assessed at the β-selection checkpoint. Most cells fail this checkpoint and die, but the coordination of fate at the β-selection checkpoint is not yet understood. We shed new light on fate determination during β-selection using a selective inhibitor of histone deacetylase 6, ACY1215. ACY1215 disrupted the β-selection checkpoint. Characterising the basis for this disruption revealed a new, pivotal stage in β-selection, bookended by up-regulation of TCR co-receptors, CD28 and CD2, respectively. Within this “DN3bPre” stage, CD5 and Lef1 are up-regulated to reflect pre-TCR signalling, and their expression correlates with proliferation. These findings suggest a refined model of β-selection in which a coordinated increase in expression of pre-TCR, CD28, CD5 and Lef1 allows for modulating TCR signalling strength and culminates in the expression of CD2 to enable exit from the β-selection checkpoint.
A Secure and Scalable Sidechain Model for Fog Computing in Healthcare Systems. (c2022)
Authors:   ,   Lebanese American University, Amhaz Ali
Published: October 2022

With the enormous amount of data produced daily, cloud and fog computing presented efficient and effective models for real-time data exchange. Nevertheless, this technology came with a cost at the security level, where it became an easy target for malicious actions that could directly spread throughout the model. Blockchain, a recent and promising technology, was a suitable solution for securing the transactions in the fog environment because of the distributed ledger structure that makes it resistant to many attacks. Scalability, however, introduced the main drawback for a blockchain by making it inefficient in some real-world applications, especially in the medical field, which includes a lot of data exchange. This work will suggest a scalable and secure model for fog and cloud computing in healthcare systems that depend on sidechains and the clustering of the available fog nodes. The importance of the model is highlighted, and experimental results showed promising outcomes.
Implementing Sustainable Development in Postwar Lebanon
Authors:   ,   Lebanese American University, Kassab Danielle
Published: October 2022

Sustainable development has been a topic of global interest for the past few decades. In 2015, the United Nations launched 17 Sustainable Development Goals (SDGs) in order to improve the quality of life of this generation and future generations. Particularly, SDG 15 titled “Life on Land” calls on member states to preserve biodiversity and protect the environment. Developed countries are finding it easier to achieve this goal, while developing countries are mostly prioritizing other challenges. Lebanon, a developing country that is politically and religiously divided, has been grappling with many internal and external conflicts resulting from its 15-year civil war that ended back in 1990. To answer the key question of the extent to which Lebanon was able to effectively pursue sustainable development, specifically SDG15, this thesis examines the work of the two entities responsible for the attainment of SDG15 which are the Ministry of Environment and local environmental groups in Lebanon. The Ministry of Environment and environmental groups have been working on protecting biodiversity and providing reforestation techniques to farmers in the country which is in line with sustainable development. However, they have both fallen behind in critical areas such as stopping land excavation (for querying stones) and building dams without due consideration to their effectiveness and environmental consequences. The thesis contends that the close relationship between the political and business elites and insufficient governmental accountability were behind these failures. Despite these structural obstacles, the Ministry of the Environment and environmental groups have been able to make some progress towards meeting SDG 15.
Comparison of Ventilatory and Blood Lactate Thresholds in Elite Soccer Players
Authors:   University of Central Lancashire - Cyprus Campus, University Avenue 12-14, 7080 Pyla, Cyprus, Parpa Koulla , Michaelides Marcos ,   University of Central Lancashire - Cyprus Campus, University Avenue 12-14, 7080 Pyla, Cyprus
Published: October 2022

Despite a long research history, the lactate threshold continues to be a widely controversial field. Notwithstanding the controversies and influence of multiple determinants, the estimation of lactate threshold in sports has been considered one of the essential parameters in the prescription of training intensity, load monitoring, and perfor- mance prediction. The study aimed to compare the anaerobic ventilatory and lactate thresholds as determined by different methods in elite soccer players. The study consisted of twenty-five division 1 elite soccer players. The players were separated into two groups based on their run times on the treadmill. Group 1 (age 24.38±7.33 years, height 180.33±7.03 cm, weight 75.53±7.68 kg) consisted of players who completed more than 17 minutes on the treadmill, while group 2 (age 25.11±6.07 years, height 182.11±10.03 cm, weight 79.72±7.54 kg) consisted of those who completed less than 17 minutes. The players completed an incremental maximal cardiopulmonary exercise testing from which ventilatory thresholds were determined. Furthermore, measurements of blood samples were obtained every 3 minutes after completing each stage of the test, with a total of 141 measurements completed. Multivariate tests indicated no significant differences in the speeds calculated with ventilatory and lactate thresh- old methods. These findings suggest that the anaerobic ventilatory threshold (VT2) can be used as an alternative to the invasive lactate threshold measurements. Therefore, identifying a threshold point without utilizing an inva- sive procedure enhances the potential application of the VT2 or respiratory compensation point.