bluuebunny/crossref_metadata_2025 huggingface dataset:
Suppression of damping in a diamagnetically levitated dielectric sphere via eddy currents and static charge reduction
Authors: Zhu Xunmin , Wu Tong , Yang Jing , Chen Zhiming , Guo Leilei , Liu Rui , Fu Zhenhai , Li Cuihong , Hu Huizhu
Published: August 2023

Diamagnetically levitated micro–nano oscillators play a crucial role in fundamental physics research and the advancement of high-precision sensors. Achieving high sensitivity in acceleration or force sensing is a fundamental requirement within these research domains. The primary limitation in achieving such sensitivity is thermal noise, which is directly proportional to the motion damping of the oscillator. Theoretical modeling suggests the presence of significant damping mechanisms induced by eddy currents. In this study, we validated the theoretical model by optimizing the structure of the magnet trap, confirming the impact of eddy currents on the damping of the oscillators. Additionally, we observed another type of damping caused by static charge in moving levitated dielectrics. Subsequently, we proposed an innovative theoretical model to explain this phenomenon and verified its validity during the charge neutralization process. Through these efforts, we successfully reduced the total damping from 1.6 mHz to 0.15 mHz, resulting in an order of magnitude improvement in performance. Our sensing system achieved the highest sensitivity of acceleration sensing in diamagnetically levitated submillimeter-scale dielectric to date, measuring 7.6±0.8)×10−10g/Hz. The exploration conducted in this study regarding the analysis and suppression of electromagnetic damping, along with associated thermal noise, holds significant promise for frontier research involving sensing with levitating dielectrics.
Zero-broadening slow light from photorefractive two-wave mixing
Authors: Bouldja Nacera , Sciamanna Marc , Grabar Alexander , Wolfersberger Delphine
Published: August 2023

The ability to delay short light pulses is a promising solution for all-optical telecommunications, but suffers from a large distortion of the delayed pulse as a consequence of the high material dispersion. In this Letter, we demonstrate the possibility to all-optically control the group delay in a photorefractive (PR) crystal by the use of the two-wave mixing (TWM) effect in the pulse regime at room temperature. Most importantly, we show that a proper choice of the pump pulse width in the TWM process enables us to slow down shorter or longer signal pulses without distortion. The technique is demonstrated both at visible (638 nm) and infrared (1064 nm) wavelengths and for slowed-down pulses with durations ranging from 10 ns up to 30 ms, hence confirming its broad applicability.
Higher Order Multipoles in Metaphotonic Structures: An Overview Of Symmetric Approaches And Providing A Comprehensive Theoretical Method
Authors: Allahverdizade Hosein , Afkari Ehsan , Aghdasinia Sina , Bemani Mohammad
Published: August 2023

This research explores localized electric fields in 2-D photonic crystals, focusing on higher order multipoles. Novel formulas are developed to accurately describe and analyze these complex electromagnetic modes. By considering various crystal element arrangements, we investigate the formation and interactions of electric, magnetic, and toroidal moments. we examine the effects of symmetry on the localized electromagnetic fields in 2-D periodic structures and explain how Bound States in the Continuum (BICs) arise and behave in different symmetry classes. It is important to point out that every singularity point which occur in multipolar series expansions depends on a BIC point and it inspire us to study the characteristic of them. Furthermore, we analyze a variety of BICs and use perturbed and degeneracy breaking to investigate high-Q factor BICs. The results provide a thorough understanding of how symmetry and multi-polar interactions affect potential applications in cutting-edge metasurfaces and photonic devices (metaphotonic).
Prediction of DNA Methylation based on Multi-dimensional feature encoding and double convolutional fully connected convolutional neural network
Authors: Hu Wenxing , Guan Lixin , Li Mengshan
Published: August 2023

DNA methylation takes on critical significance to the regulation of gene expression by affecting the stability of DNA and changing the structure of chromosomes. DNA methylation modification sites should be identified, which lays a solid basis for gaining more insights into their biological functions. Existing machine learning-based methods of predicting DNA methylation have not fully exploited the hidden multidimensional information in DNA gene sequences, such that the prediction accuracy of models is significantly limited. Besides, most models have been built in terms of a single methylation type. To address the above-mentioned issues, a deep learning-based method was proposed in this study for DNA methylation site prediction, termed the MEDCNN model. The MEDCNN model is capable of extracting feature information from gene sequences in three dimensions (i.e., positional information, biological information, and chemical information). Moreover, the proposed method employs a convolutional neural network model with double convolutional layers and double fully connected layers while iteratively updating the gradient descent algorithm using the cross-entropy loss function to increase the prediction accuracy of the model. Besides, the MEDCNN model can predict different types of DNA methylation sites. As indicated by the experimental results,the deep learning method based on coding from multiple dimensions outperformed single coding methods, and the MEDCNN model was highly applicable and outperformed existing models in predicting DNA methylation between different species. As revealed by the above-described findings, the MEDCNN model can be effective in predicting DNA methylation sites.
Structural identifiability of biomolecular controller motifs with and without flow measurements as model output
Authors: Haus Eivind S. , Drengstig Tormod , Thorsen Kristian
Published: August 2023

Controller motifs are simple biomolecular reaction networks with negative feedback. They can explain how regulatory function is achieved and are often used as building blocks in mathematical models of biological systems. In this paper we perform an extensive investigation into structural identifiability of controller motifs, specifically the so–called basic and antithetic controller motifs. Structural identifiability analysis is a useful tool in the creation and evaluation of mathematical models: it can be used to ensure that model parameters can be determined uniquely and to examine which measurements are necessary for this purpose. This is especially useful for biological models where parameter estimation can be difficult due to limited availability of measureable outputs. Our aim with this work is to investigate how structural identifiability is affected by controller motif complexity and choice of measurements. To increase the number of potential outputs we propose two methods for including flow measurements and show how this affects structural identifiability in combination with, or in the absence of, concentration measurements. In our investigation, we analyze 128 different controller motif structures using a combination of flow and/or concentration measurements, giving a total of 3648 instances. Among all instances, 34% of the measurement combinations provided structural identifiability. Our main findings for the controller motifs include: i) a single measurement is insufficient for structural identifiability, ii) measurements related to different chemical species are necessary for structural identifiability. Applying these findings result in a reduced subset of 1568 instances, where 80% are structurally identifiable, and more complex/interconnected motifs appear easier to structurally identify. The model structures we have investigated are commonly used in models of biological systems, and our results demonstrate how different model structures and measurement combinations affect structural identifiability of controller motifs.
Improving mental ill-health with psycho-social group interventions in South Asia–A scoping review using a realist lens
Authors: Mathias Kaaren , Jain Sumeet , Fraser Robert , Davis Meghan , Kimijima–Dennemeyer Rita , Pillai Pooja , Deshpande Smita N. , Wolters Maria
Published: August 2023

This scoping review aimed to synthesise current evidence related to psycho-social groups as part of community-based mental health interventions in South Asia. We used a realist lens to pay attention to the contexts and mechanisms supporting positive outcomes. We included studies published from January 2007 to February 2022 that: were based in communities in South Asia, included a group component, reported on interventions with a clear psychosocial component, targeted adults and were implemented by lay community health workers. Two reviewers extracted data on intervention components, groups and facilitators, participant demographics and enabling contexts, mechanisms and outcomes. Expert reference panels including people with lived experience of psycho-social disability, mental health professionals and policy makers confirmed the validity and relevance of initial review findings. The review examined 15 interventions represented by 42 papers. Only four interventions were solely psycho-social and nearly all included psychoeducation and economic support. Only 8 of the 46 quantitative outcome measures used were developed in South Asia. In a context of social exclusion and limited autonomy for people with psychosocial disability, psychosocial support groups triggered five key mechanisms. Trusted relationships undergirded all mechanisms, and provided a sense of inclusion, social support and of being able to manage mental distress due to improved skills and knowledge. Over time group members felt a sense of belonging and collective strength meaning they were better able to advocate for their own well-being and address upstream social health determinants. This led to outcomes of improved mental health and social participation across the realms of intrapersonal, interpersonal and community. Psychosocial groups merit greater attention as an active ingredient in community interventions and also as an effective, relevant, acceptable and scalable platform that can promote and increase mental health in communities, through facilitation by lay community health workers.
Analysis of News Media-Reported Snakebite Envenoming in Nepal during 2010–2022
Authors: Pandey Deb P. , Thapa Narayan B.
Published: August 2023

Background

Snakebite envenoming is a well-known medical emergency in the Terai of Nepal in particular. However, there is an epidemiological knowledge gap. The news media data available online provide substantial information on envenomings. Assessing this information can be a pristine approach for understanding snakebite epidemiology and conducting knowledge-based interventions. We firstly analyzed news media-reported quantitative information on conditions under which bites occur, treatment-seeking behavior of victims, and outcomes of snakebite envenomings in Nepal.

Methodology/Principal findings

We analyzed 308 Nepalese snakebite envenomed cases reported in 199 news media articles published between 2010 and 2022 using descriptive statistics, Wilcoxon, and Chi-square tests to know why and how victims were bitten, their treatment-seeking behavior, and the outcomes. These envenomated cases known with substantial information represented 48 districts (mostly located in the Terai region) of Nepal. These envenomings mostly occurred in residential areas affecting children. Generally, envenomings among males and females were not significantly different. But, in residential areas, females were more envenomed than males. Further, victims’ extremities were often exposed to venomous snakebites while their active status and these episodes often occurred at night while victims were passive during snakebites indoors and immediate surroundings of houses. Snakebite deaths were less among referred than non-referred cases, males than females, and while active than passive conditions of victims.

Conclusion/Significance

The most of reported envenomed patients were children, and most envenomings were due to cobra bites. Consultation with traditional healers complicated snakebite management. In most cases, deaths that occur without medical interventions are a severe snakebite consequence in Nepal. Further, several deaths in urban areas and mountains and higher hills of Nepal suggest immediate need of snakebite management interventions in the most affected districts. Therefore, there is an urgent need to immediately admit Nepalese snakebite victims to nearby snakebite treatment centers without adopting non-recommended prehospital interventions. The strategies for preventing snakebite and controlling venom effects should also include hilly and mountain districts where snakebite-associated deaths are reported.
Efficacy, safety, and tolerability of albendazole and ivermectin based regimens for the treatment of microfilaraemic loiasis in adult patients in Gabon: A randomized controlled assessor blinded clinical trial
Authors: Zoleko-Manego Rella , Kreuzmair Ruth , Veletzky Luzia , Ndzebe-Ndoumba Wilfrid , Ekoka Mbassi Dorothea , Okwu Dearie G. , Dimessa-Mbadinga-Weyat Lia B. , Houtsa-Temgoua Roselyne D. , Mischlinger Johannes , McCall Matthew B. B. , Kresmner Peter G. , Agnandji Selidji T. , Lell Betrand , Adegnika Ayôla A. , Mombo-Ngoma Ghyslain , Ramharter Michael
Published: August 2023

Background

There is a lack of systematic evidence for strategies to control loiasis transmission in highly endemic regions. Here we assessed albendazole and ivermectin based treatment regimens to reduce Loa loa microfilaraemia in Gabon.

Methods

Eligible adult patients with L. loa microfilaraemia between 5,000 and 50,000 microfilariae/ml were randomized to either a control or one of three intervention groups (1:2:2:2 allocation ratio) consisting of three-week twice daily 400mg oral albendazole followed by 1) no treatment, 2) two further weeks of twice daily 400mg albendazole, or 3) a single dose of ivermectin in this open label randomized assessor blinded controlled clinical trial. The primary outcome was the proportion of participants with L. loa microfilaraemia ≤ 100 mf/ml at Day 168.

Results

In the efficacy-population of 42 patients 0 (0%; control group), 1 (9%; 3-week albendazole), 5 (39%; 5-weeks albendazole) and 2 (22%; 3-week albendazole plus single dose ivermectin) participants met the primary outcome of microfilaraemia below 100/ml at day 168. A 80–90% reduction of microfilaraemia was observed in the active treatment groups.

Conclusion

The 5-week regimen of albendazole or a 3-week regimen of albendazole followed by ivermectin were most efficacious to reduce microfilaraemia. All therapeutic regimens were well tolerated and safe.

Trial registration

Trial registered at the Pan-African Clinical Trials Registry: PACTR201807197019027.
Psychometric properties of the Malay version of the difficulties in Emotion Regulation Scale-18 in Malaysian adolescents
Authors: Rosharudin Nur Afrina , Muhammad Noor Azimah , Mohd Daud Tuti Iryani , Hoesni Suzana Mohd , Yusoff Siti Rashidah , Razman Mohamad Omar Ihsan , Mohd Ali Manisah , Khairuddin Khairul Farhah , Mohd Kari Dharatun Nissa Puad
Published: August 2023

Objective

The Difficulties in Emotion Regulation Scale-18 (DERS-18) is an instrument used to measure deficits in emotion regulation. However, the instrument has not been adapted to Malaysians and has never been validated in the Malay language. This study aimed to examine the psychometric properties of the Malay version of DERS-18.

Method

The DERS-18 underwent forward-backward translation and assessment of face and content validity. Both Malay version of the DERS-18 and DASS-21 were completed by 701 adolescents (44.4% boys) aged 13 and 14 years old. To assess its dependability, a floor and ceiling effect evaluation and Cronbach’s analysis were both performed. A series of confirmatory factor analyses (CFA), bivariate correlation, and regression were performed to evaluate the construct and criterion validity, respectively.

Results

The Malay version of DERS-18, after excluding “Awareness”, indicated excellent reliability (Cronbach’s α = 0.93), and acceptable internal consistency for each subscale (range of α from 0.63 to 0.82). Floor or ceiling effects were observed at item level and subscale level, but not at total level. CFA results revealed that the Malay version of the DERS-18 bifactor model (excluding “Awareness”) portrayed the best construct validity (χ2/df = 2.673, RMSEA = 0.049, CFI = 0.977, TLI = 0.968) compared to a single factor, a correlated factor, and a higher-order factor model. The DERS-18 subscales (except “Awareness”) and DERS-18 total scores were significantly correlated with stress, anxiety, and depression in a positive direction (r ranged from 0.62 to 0.64, p < 0.01). The general factor of the DERS-18 and its specific factors (“Clarity”, “Goals”, and “Non-Acceptance”) significantly predicted the symptoms of stress, anxiety, and depression (R2 ranged from 0.44 to 0.46, p < 0.001).

Conclusion

The Malay version of the DERS-18, excluding “Awareness”, possessed good reliability, construct validity, and criterion validity to assess emotion dysregulation among Malaysian adolescents.
A wavelet based data coupling method for spatial damage detection in beam-type structures
Authors: Zhao Jianwei , Zhou Zhuo , Guan Deqing , Guo Jia
Published: August 2023

Spatial damage identification is of great significance in mechanical, aerospace, and civil engineering. In this study, a data coupling method based on continuous wavelet transform (CWT) is proposed to identify the spatial damage location of beam-type structures. The singularity of the wavelet coefficient can be used to identify the signal singularity, and data coupling method calculates the spatial location of the damage. Numerical simulations and experimental analyses of different type of beams with transfixion damage are carried out to evaluate the accuracy of the method. The results show that the wavelet based data coupling method (W-DCM) can identify the minimum 4.9% damage severity of fixed beam and continuous beam, and can also identify the damage of non-free end of cantilever beam. However, the 9.7% damage severity of the free end of the cantilever beam cannot be identified. It is also found that the W-DCM can effectively circumvent the problem of wavelet coefficients edge effect. This method and wavelet singularity are used to provide a solution to the problem of structural edge damage identification.
The pathophysiological impact of intra-abdominal hypertension in pigs
Authors: Wise Robert , Rodseth Reitze , Párraga-Ros Ester , Latorre Rafael , López Albors Octavio , Correa-Martín Laura , M. Sánchez-Margallo Francisco , Eugenia Candanosa-Aranda Irma , Poelaert Jan , Castellanos Gregorio , L. N. G. Malbrain Manu
Published: August 2023

Background

Intra-abdominal hypertension and abdominal compartment syndrome are common with clinically significant consequences. We investigated the pathophysiological effects of raised IAP as part of a more extensive exploratory animal study. The study design included both pneumoperitoneum and mechanical intestinal obstruction models.

Methods

Forty-nine female swine were divided into six groups: a control group (Cr; n = 5), three pneumoperitoneum groups with IAPs of 20mmHg (Pn20; n = 10), 30mmHg (Pn30; n = 10), 40mmHg (Pn40; n = 10), and two mechanical intestinal occlusion groups with IAPs of 20mmHg (MIO20; n = 9) and 30mmHg (MIO30; n = 5).

Results

There were significant changes (p<0.05) noted in all organ systems, most notably systolic blood pressure (SBP) (p<0.001), cardiac index (CI) (p = 0.003), stroke volume index (SVI) (p<0.001), mean pulmonary airway pressure (MPP) (p<0.001), compliance (p<0.001), pO2 (p = 0.003), bicarbonate (p = 0.041), hemoglobin (p = 0.012), lipase (p = 0.041), total bilirubin (p = 0.041), gastric pH (p<0.001), calculated glomerular filtration rate (GFR) (p<0.001), and urine output (p<0.001). SVV increased progressively as the IAP increased with no obvious changes in intravascular volume status. There were no significant differences between the models regarding their impact on cardiovascular, respiratory, renal and gastrointestinal systems. However, significant differences were noted between the two models at 30mmHg, with MIO30 showing worse metabolic and hematological parameters, and Pn30 and Pn40 showing a more rapid rise in creatinine.

Conclusions

This study identified and quantified the impact of intra-abdominal hypertension at different pressures on several organ systems and highlighted the significance of even short-lived elevations. Two models of intra-abdominal pressure were used, with a mechanical obstruction model showing more rapid changes in metabolic and haematological changes. These may represent different underlying cellular and vascular pathophysiological processes, but this remains unclear.
In silico epitope prediction and evolutionary analysis reveals capsid mutation patterns for enterovirus B
Authors: Wang Hui , Fang Yulu , Jia Yongtao , Tang Jiajie , Dong Changzheng
Published: August 2023

Enterovirus B (EVB) is a common species of enterovirus, mainly consisting of Echovirus (Echo) and Coxsackievirus B (CVB). The population is generally susceptible to EVB, especially among children. Since the 21st century, EVB has been widely prevalent worldwide, and can cause serious diseases, such as viral meningitis, myocarditis, and neonatal sepsis. By using cryo-electron microscopy, the three-dimensional (3D) structures of EVB and their uncoating receptors (FcRn and CAR) have been determined, laying the foundation for the study of viral pathogenesis and therapeutic antibodies. A limited number of epitopes bound to neutralizing antibodies have also been determined. It is unclear whether additional epitopes are present or whether epitope mutations play a key role in molecular evolutionary history and epidemics, as in influenza and SARS-CoV-2. In the current study, the conformational epitopes of six representative EVB serotypes (E6, E11, E30, CVB1, CVB3 and CVB5) were systematically predicted by bioinformatics-based epitope prediction algorithm. We found that their epitopes were distributed into three clusters, where the VP1 BC loop, C-terminus and VP2 EF loop were the main regions of EVB epitopes. Among them, the VP1 BC loop and VP2 EF loop may be the key epitope regions that determined the use of the uncoating receptors. Further molecular evolution analysis based on the VP1 and genome sequences showed that the VP1 C-terminus and VP2 EF loop, as well as a potential “breathing epitope” VP1 N-terminus, were common mutation hotspot regions, suggesting that the emergence of evolutionary clades was driven by epitope mutations. Finally, footprints showed mutations were located on or near epitopes, while mutations on the receptor binding sites were rare. This suggested that EVB promotes viral epidemics by breaking the immune barrier through epitope mutations, but the mutations avoided the receptor binding sites. The bioinformatics study of EVB epitopes may provide important information for the monitoring and early warning of EVB epidemics and developing therapeutic antibodies.
Impacts of Covid-19 on mental health service provision in the Western Cape, South Africa: The MASC study
Authors: Davies Thandi , Daniels Ingrid , Roelofse Marinda , Dean Carol , Parker John , Hanlon Charlotte , Thornicroft Graham , Sorsdahl Katherine
Published: August 2023

In the context of an already large treatment gap in South Africa, this study aimed to examine how Covid-19 and the related lockdown measures affected the availability, accessibility, quality, and continuity of mental health services in the Western Cape province in South Africa. A mixed-methods design was employed, using narrative surveys, quantitative surveys, and qualitative semi-structured interviews, with 17 public mental health providers, and secondary data from the District Health Information System. We analysed and combined the data using descriptive statistics, template analysis and methodological triangulation. Results showed that Covid-19 and the lockdowns had negative impacts on mental health service provision at all levels of care, such as reduced access to services, increased stigma and discrimination, disrupted medication supply, increased workload and stress for providers, and the closure of psychosocial and therapeutic services. Innovations used by providers to mitigate these impacts included telehealth, online training, peer support groups, and community outreach. The study concludes that Covid-19 and the lockdowns exposed and exacerbated the existing gaps and challenges in mental health service provision in South Africa. Key recommendations for policy formation and response to future pandemics in the public mental health sector include: classifying psychological treatments as essential services, establishing an intersectoral mental health emergency response plan, involving mental health care users in the development of pandemic responses, creating policies for managing health emergencies in psychiatric facilities, and increasing resources for the mental health sector in South Africa. These recommendations are relevant for South Africa and other LMICs in ensuring adequate mental health care during public health emergencies.
Self-reported benefits and risks of open water swimming to health, wellbeing and the environment: Cross-sectional evidence from a survey of Scottish swimmers
Authors: Oliver David M. , McDougall Craig W. , Robertson Tony , Grant Blair , Hanley Nick , Quilliam Richard S.
Published: August 2023

Engaging with natural environments benefits human health by providing opportunities for social interactions, enhancing mental wellbeing and enabling outdoor spaces for physical exercise. Open water swimming has seen a rapid increase in popularity, partly due to the physical health benefits it can provide but also with the growing interest in (re)connecting with nature for environment-health interactions. Using a national-scale online survey of 717 open water swimmers, the aim of this study was to investigate patterns and trends in the perceived benefits and risks of open water swimming to both public health and the environment; and to understand whether these perceived risks and benefits vary across different typologies of swimmers and open water, or ‘blue space’, environments. Strong associations were found between the most important self-reported benefit associated with open water swimming and both participant age and the categorisation of their typical swim style. All but one of the age-groups surveyed perceived mental wellbeing benefits to be the most important benefit of open water swimming; whilst those aged over 65 identified physical rather than mental wellbeing benefits to be the most important outcome. Participants who preferred lake swimming reported greater concern regarding possible environmental damage caused by the increasing popularity of open water swimming compared to those engaging in river or sea swimming. However, the majority of participants perceived the risks to the environment from open water swimming to be minimal. Our study adds to the growing evidence that open water swimming is perceived by participants as benefitting their mental and physical wellbeing. Improved understanding of the benefits and risks of engaging with blue spaces used for open water swimming can contribute to co-designed policy development to promote safer, healthier and more sustainable outdoor recreation opportunities associated with this increasingly popular outdoor pursuit.
Modelling BK Polyomavirus dissemination and cytopathology using polarized human renal tubule epithelial cells
Authors: Lorentzen Elias Myrvoll , Henriksen Stian , Rinaldo Christine Hanssen
Published: August 2023

Most humans have a lifelong imperceptible BK Polyomavirus (BKPyV) infection in epithelial cells lining the reno-urinary tract. In kidney transplant recipients, unrestricted high-level replication of donor-derived BKPyV in the allograft underlies polyomavirus-associated nephropathy, a condition with massive epithelial cell loss and inflammation causing premature allograft failure. There is limited understanding on how BKPyV disseminates throughout the reno-urinary tract and sometimes causes kidney damage. Tubule epithelial cells are tightly connected and have unique apical and basolateral membrane domains with highly specialized functions but all in vitro BKPyV studies have been performed in non-polarized cells. We therefore generated a polarized cell model of primary renal proximal tubule epithelial cells (RPTECs) and characterized BKPyV entry and release. After 8 days on permeable inserts, RPTECs demonstrated apico-basal polarity. BKPyV entry was most efficient via the apical membrane, that in vivo faces the tubular lumen, and depended on sialic acids. Progeny release started between 48 and 58 hours post-infection (hpi), and was exclusively detected in the apical compartment. From 72 hpi, cell lysis and detachment gradually increased but cells were mainly shed by extrusion and the barrier function was therefore maintained. The decoy-like cells were BKPyV infected and could transmit BKPyV to uninfected cells. By 120 hpi, the epithelial barrier was disrupted by severe cytopathic effects, and BKPyV entered the basolateral compartment mimicking the interstitial space. Addition of BKPyV-specific neutralizing antibodies to this compartment inhibited new infections. Taken together, we propose that during in vivo low-level BKPyV replication, BKPyV disseminates inside the tubular system, thereby causing minimal damage and delaying immune detection. However, in kidney transplant recipients lacking a well-functioning immune system, replication in the allograft will progress and eventually cause denudation of the basement membrane, leading to an increased number of decoy cells, high-level BKPyV-DNAuria and DNAemia, the latter a marker of allograft damage.
A justiça restaurativa na escola nos processos de educação socioemocional de estudantes adolescentes
Authors: Da Silva Pedro Rodrigo , Monteiro Ferreira Hugo
Published: August 2023

Este artigo resulta de uma dissertação de mestrado que focalizou a prática de Justiça Restaurativa Círculos de Construção de Paz no ambiente escolar. Partiu-se da hipótese de que esses círculos também podem funcionar como ambientes e momentos favoráveis à educação socioemocional de estudantes adolescentes, contribuindo para sua formação integral. A pesquisa consistiu na proposição e facilitação, pelo pesquisador, de círculos restaurativos em uma escola pública estadual pernambucana que não os realizava. Os sujeitos da pesquisa foramestudantes terceiranistas. A partir de uma abordagem metodológica transdisciplinar, elegeu-se como principal técnica de pesquisa o Círculo Virtual de Construção dePaz. As categorias analíticas estabelecidas a priori foram o autoconhecimento e o autocuidado.
Situações de produção escrita: potências e entraves da transposição didática do ensino presencial para o remoto
Authors: Russo Giulianny , Cilento Luiza
Published: August 2023

Para que as crianças se alfabetizem, é necessário que o/a docente proponha diferentes situações que as levem a ler e escrever por si mesmas. Para isso, há um conjunto de condições que devem estar garantidas para que aspropostas sejam de fato potentes. Na literatura, encontramos diversas propostas que modelizam encaminhamentos que buscam cumprir com essas condições; entretanto, estas são elaboradas considerando um contexto de ensino presencial.Motivadas pelo cenário sanitário vivido em função da pandemia de COVID-19, a qual impôs o ensino remoto como única forma possível de mediação das aprendizagens escolares, nos interessou analisar duas situações didáticasrelacionadas à escrita por si mesmo, com crianças em momento inicial de alfabetização (1º ano do Ensino Fundamental), e observar o quanto as práticas desenvolvidas se aproximaram ou se distanciaram das condições didáticasdescritas para o contexto presencial e como favorecem a aprendizagem nas situações de escrita.
1º Desafio de Ligas Acadêmicas do Colégio Brasileiro de Cirurgia e Traumatologia Buco-Maxilo-Facial (CBCTBMF)
Authors: Araújo Marcelo Marotta
Published: August 2023

No dia 04 de dezembro de 2021, foi realizado o 1º Desafio de Ligas Acadêmicas do Colégio Brasileiro de Cirurgia e Traumatologia Buco-Maxilo-Facial (CBCTBMF). O evento aconteceu remotamente e contou com a participação de sete ligas acadêmicas credenciadas no CBCTBMF: 1 - Liga Acadêmica de CTBMF da Faculdade de Odontologia de Araçatuba (Unesp); 2 - Liga Acadêmica de CTBMF do Espírito Santo (LACIBUCOES); 3 - Liga Acadêmica de CTBMF da Faculdade de Odontologia de Araraquara (Unesp); 4 - Liga Acadêmica de CTBMF da Universidade Federal do Paraná; 5 - Liga Acadêmica de CTBMF de Florianópolis (LAFACCIAL); 6 - Liga Acadêmica de Estomatologia, Patologia e Cirurgia da Unesp de São José dos Campos (LAEC); e 7 - Liga Acadêmica de CTBMF da Universidade Tiradentes de Sergipe (Unit). O evento foi idealizado pelo presidente do CBCTBMF, Dr. Marcelo Marotta Araújo, e os membros titulares Dr. Leonardo Perez Faverani, Dr. Valfrido Pereira-Filho e Dr. Rogério Belle de Oliveira; e contou com o apoio de alunos da pós-graduação e membros do CBCTBMF. O intuito foi aproximar as ligas acadêmicas de CTBMF da entidade que representa a especialidade no país, e proporcionar um evento que também contribuísse para a formação dos alunos.
Participação feminina em Cirurgia e Traumatologia Buco-Maxilo-Facial: um estudo de campo
Authors: Pereira Rebeca Maria Vieira , Ferraz Maria Ângela Arêa Leão , Falcão Carlos Alberto Monteiro , Santos Darklilson Pereira , Firmino Brunna Da Silva , Castro Marcus Victor Vaz Soares
Published: August 2023

Introdução: As mulheres, apesar das dificuldades, já conquistaram espaço em muitos âmbitos da sociedade, principalmente no que se refere ao campo de trabalho e à formação. Em 2017, por meio de um censo realizado pelo Instituto Brasileiro de Geografia e Estatística (IBGE), observou-se que as mulheres eram maioria entre os estudantes dos cursos de Odontologia e Medicina. No entanto, em algumas áreas específicas da Odontologia, a participação feminina é notavelmente diminuta, por exemplo, na Cirurgia e Traumatologia Buco-Maxilo-Facial. Objetivo: O presente trabalho teve como objetivo avaliar a participação feminina na área de Cirurgia e Traumatologia Buco-Maxilo-Facial. Métodos: Por meio de questionários enviados às cirurgiãs-dentistas inscritas no Colégio Brasileiro de Cirurgia e Traumatologia Buco- Maxilo-Facial no ano de 2018, foram analisadas a atuação e a participação delas na área. Resultados: Dos 242 questionários enviados, obteve-se retorno de 46,8%. Encontrou-se número igual de mulheres casadas e solteiras, acrescido de um novo estado civil: união estável. A maioria estava mais concentrada na região Sudeste e não tinha filhos. A especialização foi o tipo de formação mais encontrada, e a maioria não exercia docência na área. Conclusão: Apesar do preconceito sofrido, as mulheres têm apresentado interesse crescente pela Cirurgia. O aumento de cursos ofertados abriu mais espaço para o público feminino, além de ampliar o campo de trabalho.
A eminectomia como tratamento para a luxação recidivante da ATM: uma revisão sistemática
Authors: Suares Wedja Alves , Lopes André Coelho , Alves Kayo Costa , Andrade Clarisse Samara De , Sales Pedro Henrique Da Hora
Published: August 2023

Introdução: A luxação da articulação temporomandibular (ATM) é definida como uma condição fisiopatológica que pode ocorrer de forma aguda ou crônica. É caracterizada por um deslocamento do côndilo para fora de suas posições funcionais, ou seja, além da eminência articular. Objetivo: O presente trabalho tem por objetivo avaliar a efetividade da técnica de eminectomia em pacientes com luxação recidivante de ATM e as possíveis complicações associadas ao uso da técnica cirúrgica. Métodos: Buscas foram realizadas em quatro bases de dados, incluindo a literatura cinzenta (PubMed, LILACS, Central Cochrane e Opengrey), até novembro de 2021. Resultados: Nos resultados iniciais, foram encontrados 836 artigos e, após a aplicação dos critérios de inclusão e exclusão, 11 foram incluídos nessa revisão. A metanálise apresentou uma frequência de recidivas de 6,65% para eminectomia (IC 95% = 2,41 - 12,78%), com alta heterogeneidade (I² = 53,60%, IC 95% = 8,22 - 76,54%, p = 0,018). O nível de evidência científica dos estudos incluídos foi baixo. Conclusão: Conclui-se, na presente revisão sistemática, que a técnica de eminectomia mostrou-se eficiente para o tratamento da luxação recidivante da articulação temporomandibular, com menos recidivas e complicações, quando comparada a outras técnicas cirúrgicas.
Zumbido auricular tardio após redução aberta de fratura de côndilo mandibular: relato de caso
Authors: Chihara Letícia Liana , Duarte Bruno Gomes , Gonçales Eduardo Sanches
Published: August 2023

As fraturas dos côndilos mandibulares são frequentes entre as fraturas de mandíbula, devido à dissipação de forças após o trauma em outro sítio anatômico. O tratamento dessas fraturas depende do local, do nível e do deslocamento dos fragmentos fraturados, variando entre tratamento conservador e redução cirúrgica com fixação interna estável. O presente artigo teve como objetivo relatar um caso de tratamento cirúrgico de uma fratura condilar baixa e deslocada. O procedimento foi realizado em indivíduo do sexo feminino, 32 anos de idade, com instabilidade oclusal após tratamento conservador prévio por duas semanas e que evoluiu com zumbido auricular dois anos após o tratamento cirúrgico. Ela foi submetida ao procedimento de remoção do material de osteossíntese e obteve melhora do zumbido com quatro dias de pós-operatório. Conclui-se que, em casos de fraturas extracapsulares deslocadas do côndilo mandibular em adultos, o tratamento cirúrgico é o mais indicado, e que o acompanhamento desses pacientes deve ser de longo prazo.
Lubomír Doležel and his Legacy to Digital Humanities
Authors: Změlík Richard
Published: August 2023

The study focuses on that part of Lubomír Doležel’s scientific legacy which is connected with the application of quantitative and statistical methods in linguistics and literary science. In the early 1960s, the influence of information theory and cybernetics began to be strongly felt in the context of these disciplines. Alongside Jiří Levý, Lubomír Doležel was one of several linguistic researchers who creatively rethought the possibilities of these disciplines, among others, in literary science. This interest lasted, to varying degrees of intensity, until the 1980s. Although this phase of Doležel’s scholarship is usually neglected at the expense of his other works, for which he eventually became known as a world-class literary theorist, their importance is confirmed today, when quantitative methods are beginning to be used again in literary scholarship in general in the context of the digitial humanities. This study focuses not only on Doležel’s legacy to today’s literary scholarship in the digital humanities, which works with these methods, but above all highlights those of his ideas that, seen through today’s lens, have become literally timeless in this context.
Identification of rice leaf diseases and deficiency disorders using a novel DeepBatch technique
Authors: Sharma Mayuri , Kumar Chandan Jyoti , Talukdar Jyotismita , Singh Thipendra Pal , Dhiman Gaurav , Sharma Ashutosh
Published: August 2023

Rice is one of the most widely consumed foods all over the world. Various diseases and deficiency disorders impact the rice crop’s growth, thereby hampering the rice yield. Therefore, proper crop monitoring is very important for the early diagnosis of diseases or deficiency disorders. Diagnosis of diseases and disorders requires specialized manpower, which is not scalable and accessible to all farmers. To address this issue, machine learning and deep learning (DL)-driven automated systems are designed, which may help the farmers in diagnosing disease/deficiency disorders in crops so that proper care can be taken on time. Various studies have used transfer learning (TL) models in the recent past. In recent studies, further improvement in rice disease and deficiency disorder diagnosis system performance is achieved by performing the ensemble of various TL models. However, in all these DL-based studies, the segmentation of the region of interest is not done beforehand and the infected-region extraction is left for the DL model to handle automatically. Therefore, this article proposes a novel framework for the diagnosis of rice-infected leaves based on DL-based segmentation with bitwise logical AND operation and DL-based classification. The rice diseases covered in this study are bacterial leaf blight, brown spot, and leaf smut. The rice nutrient deficiencies like nitrogen (N), phosphorous (P), and potassium (K) were also included. The results of the experiment conducted on these datasets showed that the performance of DeepBatch was significantly improved as compared to the conventional technique.
Uniform Prospectus Liability Rules for Europe
Authors: Busch Danny , Lehmann Matthias
Published: August 2023

In this contribution, we make the case for the introduction of uniform rules on liability for incorrect or incomplete prospectuses relating to financial instruments offered in the European Union (EU). We set out the reasons for such uniformisation, in particular the need to complete the Capital Markets Union, the insoluble conflict-of-laws problems created by prospectus liability, and the discriminatory treatment of investors resulting from the application of different national laws to the issue. We show that uniform rules are possible, drawing a parallel to the recently adopted Markets in Crypto-Assets Regulation (MiCAR) and other EU texts. We also demonstrate that the EU has the competence to adopt such rules, and that concerns about subsidiarity and proportionality are unfounded.
US Prospectus Liability – An Overview and Critique
Authors: Steinberg Marc I
Published: August 2023

This article addresses prospectus liability in the United States. The key statutes and Securities and Exchange Commission (SEC) rules and regulations are examined in conjunction with analysis of the causes of action and defenses that are applicable. While the US prospectus framework is thorough, substantial gaps exist that should be remedied. The article accordingly focuses on principal aspects of US prospectus liability exposure and proffers recommendations for improving the overall framework.
Prospectus Liability in Europe: The Relevant Breach of Duties
Authors: Lucantoni Paola
Published: August 2023

This article focuses on the relevant breach of duties under art 11 of the Prospectus Regulation (EU) 1129/2017, which provides only few elements of the private enforcement model, leaving the specific choices of the civil liability regime to the Member States. The main purpose of this paper is to underline the contradiction that exists between (i) a rigid formalism in the Prospectus Regulation and the extensive administrative rulebook and related soft law, which imposes binding formats and contents of prospectuses in order to enhance maximum harmonised investor protection and reduce issuers’ costs in Europe, and (ii) the existing different prospectus liability regimes among the European Member States, which undermine the effectiveness of Union law on prospectuses. In order to highlight this contradiction, the contribution analyses the different legal bases of prospectus liability provided in a sample of Member States, focusing on the different (and sometimes conflicting) methods of defining, from the defendant’s side, the persons responsible and liable for the incompleteness or the incorrectness of the prospectus, and, from the plaintiff’s side, the persons who can sue for damages. In this scenario, the Court of Justice of the European Union (CJEU) has recently brought some clarity as regards the potential scope of prospectus liability claims, thus revealing how important it is to solve the above-mentioned contradiction soon.
Management of the Community Forests of Rogho and Boala in Central-West Burkina Faso: Balancing Access to Information and Peasant Participation
Authors:   Department of Geography, Laboratory of Humanities and Social Sciences, (LABOSHS), Université Norbert Zongo, Kasimou Tiamaiyu , Yanogo Isidore Pawendkisgou ,   Department of Geography, Laboratory of Humanities and Social Sciences, (LABOSHS), Université Norbert Zongo
Published: August 2023

In a dual context characterized, on the one hand, by the proliferation of forest areas made possible by initiatives such as “one department, one forest”, and on the other hand, by the devolution of the management of these forest areas to local populations through decentralization, it is necessary and opportune to investigate the management of these forest resources. Thus, the objective of this study was to analyze the management of two community forests by examining the access of local residents to information related to these forests and their participation in their management. To this end, quantitative data were collected from 201 households living near these forests. The Likert scale, consisting of four possible options, was used to assess the level of access of local residents to information related to the forests and the extent of their participation in forest management. The results of this analysis revealed respective overall mean scores of 3.59 for information access and 2.89 for participation in management, indicating a high level of information access and a moderate degree of peasant participation in forest management. These farmers should be encouraged to maximize their participation in the management of the forests to which they are adjacent.
Examining Countermovement Jump Strategies Between Women's NCAA Division I Sports
Authors: Donahue Paul T. , Peel Shelby A. , Rush Megan , McInnis Ayden Klaire , Littlefield Thomas , Calci Courtney , Brutofsky Tony
Published: August 2023

Donahue, PT, Peel, SA, Rush, M, McInnis, AK, Littlefield, T, Calci, C, and Brutofsky, T. Examining countermovement jump strategies between women’s NCAA Division I sports. J Strength Cond Res 37(10): 2052–2057, 2023—The purpose of this study was to examine countermovement vertical jump performance among female athletes who rely heavily on vertical jump performance within their given sport. Forty-five female athletes representing 3 teams (basketball, volleyball, and beach volleyball) competing at the NCAA Division I level completed 2 maximal effort countermovement jumps (CMJ) using a portable force platform. A 1-way analysis of variance was used to compare groups across each variable. Statistically significant differences were found between the groups regarding propulsive duration and time to takeoff with basketball showing the shortest time and beach volleyball having the longest times (p < 0.05). In addition, differences were seen in countermovement depth and mean propulsive force between the groups with basketball displaying the smallest countermovement and highest force (p < 0.05). No differences were seen in jump height and reactive strength index modified. Greater force and shorter durations in basketball athletes versus the low force and long durations in the beach volleyball athletes suggest that sporting backgrounds play a large role in how the CMJ is performed. This information can aid strength and conditioning practitioners in the design of training programs that are sport specific to the strategies used by the athlete.