bluuebunny/crossref_metadata_2025 huggingface dataset:
Spinal column injuries: from the very beginning
Authors: Mikhaylovskiy M. V. , Zlobin A. V.
Published: October 2024

The history of medicine is interesting and instructive. In each of the many branches of medical science, the specificity of pathology determines diagnosis and treatment. These processes inevitably continue in time and space in accordance with the conditions existingin a given place and in a given period of time. Spine injury is one of the most striking examples of the longevity and duration of this process.Humanity relatively recently discovered what diabetes is and how it should be treated, but this branch of medicine also has its own history, although not a very long one. Spinal injuries have accompanied man and his predecessors almost always, disrupting the usual rhythmof life, and therefore they have been required to be treated since time immemorial. A true professional is always interested in the history of his specialty. Spine surgeons are no exception. What we managed to collect bit by bit, of course, is not everything, but it is impossible to grasp the immense, and it is necessary to know the past in order to better understand the present and the future.
Cardiomyopathy characterizing and heart failure risk predicting by echocardiography and pathoanatomy in aged male mice
Authors: Du Xiao‐Jun , Feng Xin‐Heng , Ming Zi‐Qiu , Kiriazis Helen
Published: October 2024

Correlation between echocardiographic and pathoanatomic variables and their prognostic value in murine cardiomyopathy models remain unknown. Using echocardiography, morphometrics, and survival monitoring, we characterized transgenic (TG) mice with dilated cardiomyopathy due to cardiac overexpression of β2‐adrenoceptors focusing on predicting heart failure (HF) risk and HF mortality. In 12‐month‐old non‐TG and TG mice, echocardiography was performed to determine left ventricular (LV) dimensions (d), wall thickness (h), and fractional shortening (FS). Animals were monitored for 3 months for survival. Organ weights and pathological events indicating left HF were determined. TG mice (n = 76) had reduced FS and enlarged LV, and 79% died of HF or likely arrhythmias during the follow‐up period while all non‐TG mice (n = 26) survived. These mice with left HF also had pulmonary congestion and hypertrophy/dilatation of the right ventricle (RV). Weights of lungs, RV, and atria were intercorrelated (r = 0.79–0.83) and also negatively correlated with FS × (h/d) index (r = −0.502 to −0.609). By FS × (h/d) tertiles, TG mice of low tertiles were identified with the highest mortality (96%) largely due to HF (76%). In conclusion, in aged cardiomyopathy mice a good correlation existed between echocardiographic and pathoanatomic variables. Echocardiography‐derived LV function and remodeling were useful in identifying a subgroup of TG mice with a high risk of HF and HF fatality.
Shaping Tomorrow’s Chemistry: Reflections and Goals from IUPAC’s Vice President
Authors: Garson Mary
Published: October 2024

I first heard about IUPAC in 1972 in undergraduate organic (nomenclature) lectures; I already knew about the Periodic Table from high school days, but I did not make the connection between this chemistry and the organisation named IUPAC until much later. In 1996, I became involved in planning for Australia to bid for a General Assembly (GA)/World Chemistry Congress (WCC); ultimately the bid was successful, and the meeting was held in my home city of Brisbane in July 2001. In the way, I learnt much about the various component parts of IUPAC while the Executive Secretary role, which I held for a trio of combined meetings including an Asian Chemistry Congress plus an Asian Federation of Medicinal Chemistry meeting, brought me into contact with the IUPAC leadership. I also interacted with Titular Members, many volunteers, as well as key movers and shakers within the chemistry field. And I got to know our wonderful current IUPAC staff members Fabienne Meyers and Enid Weatherwax.
Exploring the Capabilities of ChatGPT in Ancient Chinese Translation and Person Name Recognition
Authors: Si Shijing , Zhou Siqing , Zhang Yugui
Published: October 2024

This study examines the potential of ChatGPT, notable for its skill in standard modern languages, in the context of ancient Chinese. We focus on two fundamental tasks: translating ancient Chinese into modern Chinese and identifying ancient Chinese names. We conduct experiments on Shi Shuo Xin Yu, which is a collection of anecdotes, short conversations, and pithy observations on personalities who lived in China between about 150 and 420 A.D. We also include other methods, like Baidu Yiyan (ERNIE-Bot) for ancient-to-modern translation, and SIKU-RoBERTa for ancient Chinese name recognition. The results reveal that ChatGPT’s performance in ancient Chinese remains in need of enhancement, but it excels in the task of ancient-to-modern translation with the provision of a few context sentences. For the ancient Chinese name recognition, ChatGPT can outperform SIKU-RoBERTa model in terms of precision, but suffers from low recall.
Relational description as pivotal to dialogical translation
Authors: Cipriani Gerald
Published: October 2024

Depending on whether translation leans toward objective rendering or subjective interpretation it will have different truth-functions. This essay reflects on the issues of truth-function at stake on both sides of the “hosting” language (translation) when seeking to understand “otherness” (original language). The essay will draw from particular examples of translation of Chinese thought such as the literal renderings of the Classics in Western languages, Li Zehou’s concept of “subjectality” (zhutixing 主體性) and François Jullien’s Western-inverted “deconstruction”. The point here is not to establish validity in translation, but to describe what are the cognitive and ethical implications when understanding and performing translation – a relational description thus presented as precondition for the possibility of translation-as-dialogue.
The future is only the beginning
Authors: Rock Joeva Sean , Montenegro de Wit Maywa , Kingiri Ann , Schnurr Matthew A.
Published: October 2024

Recent advancements in genome editing have captured the attention of scientists and policymakers, who contend that the technology has a large role to play in advancing food and climate security on the African continent. However, the modest results of earlier generations of biotechnology—such as genetically modified (GM) crops—raise questions about the sustainability of new technological interventions. This special feature examines lessons learned from previous generations of GM crops and other agricultural technologies, using them to analyze the portfolio of gene edited crops being developed for African farmers today. In this article, we introduce the 6 papers that make up the special feature by way of examining future-oriented discourses around the advancement of genome editing. Drawing on Science and Technology Studies, political ecology, and critical development studies, this introduction highlights the crucial factors that shape technology development, agricultural practice, and the politics of knowing and emphasizes the need to look toward multiple, diverse futures.
The Effects of Household Chaos on the Self-Determination of Young Children: The Mediating Effects of Children’s Attention
Authors: Min Boonhong , Shin Nary
Published: October 2024

The purpose of this study is to verify direct and indirect effects of household chaos on the self-determination of young children by focusing on the mediating effects of children’s attention. The subjects of the study were 267 5-year-old children, their mothers, and 21 homeroom teachers. To analyze the mediating effect of children's attention in the relationship between household chaos and children's self-determination, Model 4 of SPSS PROCESS macro proposed by Hayes (2018) was applied. The findings of this study indicate that household chaos has a significant effect on children's self-determination in educational settings by influencing their attention span subsequently. This suggests that maintaining a certain level of stimulation in the home is important for the development of children, as excessive levels of unpredictable stimuli hinder children's attention and negatively affect their self-determination. The study is meaningful in that it provides basic data for promoting self-determination in the field of early childhood education by analyzing factors that affect children's self-determination. Furthermore, the study implications suggest that the study can be used as theoretical data for teacher and parent education to promote the development of self-determination of young children.
The Development Process and Experiences of Online Interpersonal Relationships among College Students
Authors: Kim Min-Ju , Song Yeon-Joo
Published: October 2024

This study intends to suggest a way to help college students build healthy interpersonal relationships in online space by looking at the online interpersonal development process and what they experience in the process. To this end, in-depth interviews were conducted with 10 college students who have been in a relationship for more than six months online and analyzed using a qualitative content analysis method. As a result, the participants of this study began to establish relationships through games and social networking services (SNS), and began to communicate naturally by adding friends or sharing the same interests in the game. Participants gradually formed an inner intimacy by self-opening with those they met online but shared more daily life by sharing personal contact information or favorite activities together. As the number of times met while feeling inner intimacy increased, they became close and special to each other. Participants gained confidence through online relationships and expanded their relationships by meeting various people non-face-to-face. Because it was non-face-to-face, I was able to treat the other relationships more comfortably, by listening to each other, asking for advice, and experiencing growth and development together. This study suggests that being online is a place for active relationship formation for college students.
ТРЕХМЕРНОЕ МОДЕЛИРОВАНИЕ РАСПРОСТРАНЕНИЯ ОБЛАКА ВЗВЕШЕННОЙ ПЫЛИ ЗА ПРЕДЕЛАМИ ГОРНОРУДНОГО КАРЬЕРА ПРИ МАССОВЫХ ВЗРЫВАХ
Authors: ХАЗИНС В.М. , ШУВАЛОВ В.В. , СОЛОВЬЕВ С.П.
Published: October 2024

Методами численного решения полной системы уравнений Навье - Стокса для сжимаемой жидкости в дозвуковом приближении исследован перенос ветром облака взвешенной пыли в атмосферном пограничном слое территории, прилегающей к горнорудному карьеру. Источник пыли - массовый взрыв с суммарной массой заряда ~ 100 т тротила, расположенный на уступе борта карьера на глубине 250 м. В расчетах учитывается часть пыли источника, поднявшаяся в результате взрыва над дневной поверхностью карьера. Проведены оценки размеров области, где концентрация взвешенной пыли над поверхностью превышает предельно допустимые значения. Исследована зависимость этих размеров от угла α между направлением ветра и бортом карьера. Показано, что максимальное расстояние от борта карьера, на котором концентрация пыли превышает предельно допустимые значения, составляет 3 км. Длительность воздействия в фиксированных точках над поверхностью не зависит от угла α и растет от нескольких минут на расстоянии 500 м от центра взрыва до десятка минут на расстоянии 3 км.

Wind transport of an air-borne dust cloud in the atmospheric boundary layer in the neighborhood area of a surface mine is analyzed by numerical solution of the Navier-Stokes equations in their full form for a compressible liquid and in a subsonic flow approximation. The dust source is a large-scale blast at a total mass of ~ 100 g of TNT at a depth of 250 m in the pitwall rock mass. The calculations take into account a portion of dust raised above ground surface by blasting. The size of the surface areas of air-borne dust concentrations above maximal allowable values is estimated. The relationship of this size and the wind direction-pitwall angle α is analyzed. The maximal distance between the pitwall and the area of dust concentration above MAV is 3 km. The exposure duration at the fixed point on ground surface is independent of the angle α and ranges from a few minutes at a distance of 500 m from the blast center to a dozen minutes at a distance of 3 km.
ИДЕНТИФИКАЦИЯ ОБЪЕКТОВ РАЗМЕЩЕНИЯ ОТХОДОВ ГОРНОПРОМЫШЛЕННОГО КОМПЛЕКСА ПО ДАННЫМ ДИСТАНЦИОННОГО ЗОНДИРОВАНИЯ
Authors: ГАЛЧЕНКО Ю.П. , ОЗАРЯН Ю.А. , КОЖЕВНИКОВА Т.В. , ОКЛАДНИКОВ В.Е.
Published: October 2024

Предложена методика анализа спутниковых снимков для мониторинга состояния поверхности объектов согласно данным дистанционного зондирования Земли. Представлены результаты исследований по разработке алгоритма выделения объектов размещения горнопромышленных отходов. В качестве исходных данных рассмотрены снимки территорий юга Дальнего Востока со спутников Sentinel 2, Landsat 5 - 8. На базе облачной платформы Earth Engine рассчитано значение вегетационного индекса для каждого пикселя с помощью функции нормализованной разности и создана исследуемая область посредством стандартного инструмента. Для преобразования пикселей в площадь использован метод reduce. Разработанный метод актуален для мониторинга различных объектов (хвостохранилищ, карьеров, отвалов и т. д.), находящихся в разных стадиях развития.

The article presents an analysis procedure for remote sensing imagery for monitoring ground surface objects. The studies on development of an algorithm for identifying mining waste disposal facilities on ground surface are described. The source data were Sentinel-2 and Landsat 5-8 images of the southern area in the Russian Far East. Using Earth Engine platform, the vegetation index is calculated for each pixel using the function of normal distance, and the test area is generated using a standard tool. Pixels were converted to square units using the reduce() method. The proposed procedure is of current interest in monitoring various objects (tailings ponds, surface mines, waste dumps, etc.) at different stages of development.
Effect of treating birch kraft pulp with peracetic acid before O2-delignification on the properties of pulp and consumption of ClO2 in D0ED1 bleaching
Authors: Danielewicz Dariusz
Published: October 2024

The influence of pre-treating Kappa number of 18.0 industrial birch kraft pulp with peracetic acid (Paa) before oxygen delignification (OD) was studied relative to the pulps’ level of delignification, yield, brightness, intrinsic viscosity (IV), FS-number, tear index (TI), and the consumption of chlorine dioxide (ClO2) in its subsequent Elemental Chlorine Free (ECF) bleaching. The study showed that such pretreatment is a way to extend the delignification of such pulp quite selectively in OD based on values of IV, FS-number, and TI, and to reduce significantly the consumption of ClO2 required to bleach this pulp to a brightness of 87%. This reduction depended on the amount of Paa used for pulp pretreatment. For example, when 0.33% and 0.66% as active oxygen (A.O.) of Paa were used, ClO2 consumption to bleach the pulp to 87% was lowered by 15.4% and 42.3%, respectively. As high as a 61.5% reduction in ClO2 consumption in its bleaching could be obtained using 0.66% as A.O. on pulp and change of time of OD. This result allows for a significant decrease in the chlorine passing to the filtrates from washing the pulp after the D0 and E stages to the pulp mill wastewater treatment plant.
Some not Military Remarks on the Glory of Lithuanian Arms. - Reference for: Lesčius V. Lietuvos kariuomenė 1918-1920 m. Vilnius, 1998
Authors: Kaubrys Saulius
Published: October 2024

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New Dissertation on Woman's status in the Medieval Lithuania
Authors: Petrauskas Rimvydas
Published: October 2024

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The impact of increased screen time on students during covid-19 school closures
Authors: Elsaid Ahmad , Abdelwahab Abdellatif
Published: October 2024

This article is a review performed through an extensive review of previous research. Its purpose is to provide a concise overview of the current knowledge regarding the effects of increased screen usage on kids during the COVID-19 school closures. Our objective was to offer a thorough and all-encompassing examination of the current body of research, scrutinizing and deliberating on the methodologies and findings of previously conducted studies pertaining to the subject matter. The global transition to remote learning during the COVID-19 epidemic resulted in an unprecedented increase in the amount of time students spent using screens. Recent research has indicated that children' screen usage has increased by an average of 11.5 hours per week during school closures. This large growth has had significant effects on students' physical health, mental well-being, and educational achievements. Further digital literacy and access to a wide range of learning tools are two good results. However, there have been proven adverse consequences, including musculoskeletal pain, eye strain, anxiety, sadness, and declining in educational inequalities. In addition to highlighting the benefits and challenges of more screen time, this article shows ways to reduce its negative impacts, including managing screen time, exercising, and engaging in mindfulness exercises. The essay also examines what it means for educators, parents, and lawmakers highlighting the importance of adopting well-rounded strategies for digital learning that protect student well-being and ensure fairness. It also emphasizes how important it is to conduct additional study in order to comprehend the long-term impacts and create efficient solutions catered to various demographics.
Difficulties and efforts of nursery teachers in communicating with parents
Authors:   Research Institute for Early Childhood Education - Korea National University of Education, Kim Eun-Hye , Yeo Sun-Joo
Published: October 2024

This study tried to investigate the difficulties experienced in communication between childcare teachers and parents at early childhood education institutions and the efforts of teachers to overcome them. To this end, we conducted in-depth interviews from June 26 to September 31, 2023 with 10 care teachers currently working at early childhood education institutions and analyzed the data collected. The results of the study are as follows. First, childcare teachers had a lot of difficulties communicating with parents while working at an early childhood education institution. Second, care teachers made various efforts to communicate smoothly with their parents and made efforts to build trust with their parents. Third, care teachers wanted the director to act as a supporter and become a reliable person, and they wanted various support to protect teachers at a national level by demanding various educational opportunities. These results can be used as meaningful data for smooth communication between care teachers and parents at early childhood education institutions.
Teacher's experiences in Hangeul education using picture books to first grade students in elementary school
Authors:   Research Institute for Early Childhood Education - Korea National University of Education, Lee Eun-Young , Ahn Jung-Eun
Published: October 2024

The purpose of this study is to investigate educational values and possibilities of application by analyzing teacher’s experiences in teaching Hangeul using picture books to first grade elementary school students. The participant is teacher A working at Seoul B Elementary School. This study conducted the procedures of curriculum analysis, picture book selection, and making Hangeul lesson plans using picture books from February 20th to March 31st, 2023, and implemented lessons for a total of 16 times from April 3rd to May 19th, June 12th to June 27th, 2023. Data were collected and analyzed qualitative data such as interviews, teacher journals, activity results, and photos. The results are as follows. The teacher experienced lessons that had students focused regardless of their individual differences, were playful rather than academic, facilitated voluntary reading and writing, had the teacher fun and excitement, had fellow teachers want to apply lessons and required sufficient number of class hours and assistants. In conclusion, this study is meaningful in that Hangeul education using picture books has educational significance to both teachers and students and it is a practical and effective teaching-learning method in school.
Challenges and Opportunities in Transitioning Autistic Individuals Into Adulthood
Authors: Roux Anne M. , Chvasta Kyle , McLean Kiley J. , Carey Meghan , Perez Liz Georgina , Tomczuk Liza , Lopez Kristina , Assing-Murray Evva , Shattuck Paul T. , Shea Lindsay L.
Published: October 2024

BACKGROUND AND OBJECTIVES

Approximately 1.2 million autistic youth will reach the legal age of adulthood over the next decade. Given dynamic changes in the socioecological context of the transition to adulthood, we produced an updated transitions research agenda reflecting the perspectives of autistic young adults, care partners (parents), and professionals who use autism research.

METHODS

We conducted 9 focus groups: 4 young adult, 4 care partner, and 1 professional, with 59 total participants. Young adults were grouped by self-reported identity: (1) racial and ethnic minority, (2) lesbian, gay, bisexual, transgender, queer, intersex, asexual, and other identities, and (3) nonspeaking, in addition to a general group. We selected care partners who supported youth with varying intensity of support needs. We used rapid qualitative inquiry methods to extract key points from answers to semistructured interview questions.

RESULTS

Delays in diagnosis and transition processes, and placement on wait lists resulted in significant obstacles to successful transitions. Parents assumed a dominant role by coordinating services, navigating systems and identifying opportunities for community participation, and providing direct supports. There was an overarching need for inclusion of autistic people in transitions research and consideration of cultural differences in priorities and values. Participants prioritized investigation of variation in transitions among autistic youth with intersecting identities, navigation support (eg, peer mentors), efficacy of services and supports (eg, transition and employment services), differences in available services by location, and problems within specific benefits programs.

CONCLUSIONS

Research should focus on understanding population-level factors of system performance on outcomes and support needs, service delivery among marginalized groups, and transformation of complex service ecosystems.
Emotional difficulties mediate the impact of adverse childhood experiences on compulsive buying-shopping problems
Authors: David Jonathan , Kim Hyoun S. , Hodgins David C. , Dawson Samantha J. , Tabri Nassim , Shead N. Will , Keough Matthew T.
Published: October 2024

Background

Compulsive buying-shopping is recognised as a significant mental health concern, yet its aetiology is largely understudied. A known risk factor for compulsive buying-shopping is adverse childhood experiences (ACEs). ACEs are also associated with greater problems regulating emotions, as well as depression and anxiety. These factors are also known to be associated with compulsive buying-shopping problems. In this study, we aimed to test a serial mediation model in which ACEs were associated with compulsive buying-shopping problems via emotion dysregulation, and then emotional psychopathology (depression, anxiety).

Methods

We tested this model cross-sectionally in two large samples (N = 1,868 & 4,742) to evaluate the robustness of the model. Both samples completed self-report measures of ACEs, emotional dysregulation, compulsive buying, depression, and anxiety symptoms.

Results

We found support for indirect effects, and all results were consistent for both samples. ACEs predicted greater emotion dysregulation, which then predicted greater depression and anxiety. In turn, anxiety (but not depression) predicted compulsive buying symptoms.

Discussion and conclusions

Emotion dysregulation and anxiety consistently mediated the relationship between ACEs and compulsive buying symptoms. Both emotion dysregulation and anxiety represent malleable targets in clinical interventions for compulsive buying-shopping problems. Our findings also suggest that anxiety may be a stronger predictor of compulsive buying compared to depression, which may be an important avenue for future researchers to investigate.
Illusions of control: A quasi-experiment comparing skill-based and traditional slot machines
Authors: Rockloff Matthew , Russell Alex M. T. , Hing Nerilee , Browne Matthew , Thorne Hannah , Newall Philip , Visintin Tess
Published: October 2024

Background and Aims

Electronic gaming machines (EGMs) are a significant source of gambling spend due to their widespread use. Skill-based gambling machines (SGMs) represent an innovative adaptation, merging EGMs' chance-based rewards with video game-like skills. This study aimed to explore the appeal and behavioural consequences of playing SGMs in comparison to traditional reel-based EGMs, particularly focusing on illusions of control, betting behaviour, and the subjective experience of gamblers.

Methods

Participants (N = 1,260) were recruited online and engaged in an online task simulating either an SGM or a reel-based EGM, with outcomes represented to influence their survey compensation. The study examined the effect of SGMs relative to EGMs on bet size, persistence, enjoyment, illusions of control, game immersion, and the influence of demographic and gambling problem severity.

Results

SGMs particularly appealed to younger adults, regular EGM players, and people with more gambling problems. Despite identical payout structures, people assigned to play SGM showed greater illusions of control, believing in the influence of skill on game outcomes and that practice could improve results. However, there was no significant difference in overall betting intensity between SGM and EGM players, although specific demographic groups showed faster betting speeds in SGMs.

Discussion and Conclusions

SGMs, despite not inherently encouraging higher betting intensity, attract vulnerable groups and create illusions of control, posing new regulatory challenges. The visual and interactive features of SGMs, while appealing, might contribute to these perceptions, indicating a need for careful regulation and further research on their long-term impacts on gambling behaviour and harm.
Case Study on Climate Change Education in Pre-service Teachers -with the Focus on Earth Hour Activities-
Authors: Kim Yunji , Cheong Cheol
Published: October 2024

The purpose of study is to introduce a case in which education for climate action, the 13th goal of sustainable development, is established in universities through climate change classes opened in the Earth Science education department of the college of education. Climate change education, including earth hour activities, was conducted in the Inquiry of climate change education subject in the first-year major elective area. Fifty-three pre-service earth science teachers participated in a climate change class. In this study, lectures on 12 topics were conducted, and group activities such as Earth Calendar, Earth Hour, Joobging Project, and Campus Environmental Maps were conducted in parallel. Pre-service teachers recognize climate change in connection with our daily lives, but focused on artificial factors rather than natural factors. They responded positively to the climate change class and evaluated the items of interest, excitement, and satisfaction highly. In addition, the applicability of earth hour activities was confirmed as an example of climate change education programs. It provided pre-service teachers with the experience of participating in international environmental campaigns as global citizens. Climate change curriculum is needed not only in high schools but also in universities, especially in the college of education. Research on developing and implementing climate change education programs centered on universities must be sustainable.
U.S. corrections officers’ discourse about dementia
Authors: Davis Boyd H. , Troutman-Jordan Meredith
Published: October 2024

The United States has more prisoners than any other country in the world: more than 1.5 million persons were housed in state and federal prisons in 2020. A sizeable percentage are ageing; Physician’s Weekly estimates that by 2030, people aged over 50, the age at which the incarcerated are considered to be ‘old’, will make up one-third of the U.S. prison population. That group will include a great many persons who have or are developing dementia and who are guarded by correctional officers. We can, then, consider that correctional staff as well as prisoners form an overlooked dementia care minority. Using conversation and discourse analysis, we focus on epistemic modal adverbs as discourse mark-ers in spoken commentary by current correctional officers about prisoners with dementia, as some markers can signal an uneasiness with which they position themselves as knowledgeable about rights and duties in ageing and dementia. Officers frame their discourse to identify concerns about a prison system that deals poorly with inmate losses of cognitive ability and memory and suggest a need for additional training and support in communicating with incarcerated older prisoners who may have dementia.
Intraoral Approach for Dental Implant Placement in Pneumatized Maxillary Sinuses With Postoperative Maxillary Cysts: A Report of Two Cases
Authors: Park Won-Bae , Lim Hyun-Chang
Published: October 2024

A postoperative maxillary cyst (POMC) is a delayed complication of the original Caldwell-Luc operation, which was once widely performed to treat chronic rhinosinusitis. Two patients who had previously undergone Caldwell-Luc operations desired dental implant treatment. In both cases, preoperative cone-beam computerized tomography (CBCT) revealed a POMC occupying the entire maxillary sinus on the side where the implants were to be placed. The residual bone height was 3–4 mm. Furthermore, the sinuses were divided into compartments by septum-like structures. An intraoral approach was applied for POMC enucleation and implant placement. The implants were placed with sinus floor penetration due to the small residual bone height. No bone substitute material was grafted in the sinus. Postoperative healing was uneventful. All implants were successfully osseointegrated and performed well (4 and 5 years for each patient). No sinonasal complications were reported. Follow-up CBCTs showed that the exposed implant parts were covered by newly formed bone. The intraoral approach is a feasible option for implant placement in a pneumatized maxillary sinus with POMC.
A Biomechanical Comparative Analysis of Abutment Screw Head Designs on Preload Stability Under Oblique Compressive Forces: An In Vitro Pilot Study
Authors: Kwan Jan C.
Published: October 2024

The purpose of this study was to examine the impact of abutment screw head sizes on preload stability when secured to a standard external hex implant under oblique compressive forces. Fifteen metal crowns were divided into 3 equal groups. The first group had 5 angulated cemented crowns connected to a 3-mm-tall straight hexagonal abutment with an external hex abutment screw. The second and third groups each had 5 straight cemented crowns attached to a tapered abutment with flat-slotted and internal hex abutment screws, respectively. Samples were subjected to a static cyclic load until failure. Kruskal-Wallis H, Dunn, and one-way analysis of variance with Tukey honestly significant difference tests were performed. Cemented straight crowns supported by an angled abutment connected to implants with flat-slotted and internal hex abutment screw heads failed at an average of 4.24 × 106 cycles ± 3.31 SD and 12.67 × 106 cycles ± 5.47 SD, respectively. Cemented angled crowns supported by a straight abutment connected to identical implants with an external hex abutment screw survived 18.02 × 106 cycles ± 4.49 SD. The periotest value rate of change increased at a higher rate in crowns supported by angled abutments compared with straight abutments (p < .05). No cement failure was observed. Under the experimental conditions, larger abutment screw head sizes demonstrated greater stability of the abutment-abutment screw joint interface. Based on the in vitro findings, no cement failure was observed between the cemented crown and abutment connection. Future research with standardized comparative setups and larger sample sizes is needed.
Treatment of Induced Mesenchymal Stem Cells in Ischemic Heart Diseases: Hypoxia
Authors: Gurpinar Özer Aylin , Dal Irmak
Published: October 2024

When traditional methods fall short in treating ischemic heart diseases caused by reduced blood flow to the heart due to narrowed coronary arteries, alternative solutions such as cellular therapies are thought. Mesenchymal stem cells (MSCs) are advantageous due to their ease of isolation, migration, and immunomodulatory properties. Preconditioning, which involves regulating cell functions through external stimuli, enhances the effectiveness of cellular therapy. Hypoxia, known as oxygen deprivation, is known to regulate cell survival, migration, and differentiation capabilities. This review explores the current state and future of hypoxia preconditioning in enhancing the therapeutic effects of stem cells.
CURRENT STATE AND DEVELOPMENT PROSPECTS OF THE SOY MARKET IN UKRAINE
Authors: Turpurova T. , Kurbatov S.
Published: October 2024

The growth of the population in the world provides increased demand for soy and its processing products. Because in low-income countries, soy and its processing products are used as a cheap vegetable protein for human nutrition, and in developed countries - as a valuable protein raw material in animal feed. The article calculates the cost of 1 kg of raw protein in protein feeds of plant and animal origin. The cost of vegetable feed per 1 kg of protein is 1.5-3.5 times lower than the cost of animal feed. The dynamics of global soybean production are shown, which indicates that in 2023/24 it was about 395 million tons. The main soybeanproducing countries are Brazil, the USA, and Argentina, whose share in the total world production is more than 80%. The dynamics of soybean production and processing in Ukraine is presented. The largest soybean processors in Ukraine are such companies as Bunge, AdamPolSoya, Cargill, Kreativ OEP, Kyiv-Atlantic, Royal Taste, Vinnytsia OEP and others. The soybean market in Ukraine demonstrates significant success both in cultivation and in export and processing. Despite the difficult conditions caused by military actions and economic challenges, Ukrainian farmers were able to reach historical highs in the production and export of soybeans, ensuring high product quality and competitive prices on the world market. Soy is an export-oriented crop, about ? of which is delivered abroad in the form of raw materials or processed products. The largest importers of Ukrainian soybeans are the European Union, Egypt and Turkey. In connection with the innovations in the supply of soybeans to the EU, soybean producers must not only grow (use of high-quality, certified seed material, mineral fertilizers, general production and administrative costs), but also have a certificate of traceability and confirmation of the absence of deforestation throughout the production chain. Since the violation of EUDR provisions can lead to serious consequences and sanctions, namely fines of up to 4% of the total annual turnover of the enterprise for the previous financial year, confiscation of products, temporary exclusion from procurement procedures and access to public funding, including tender procedures and subsidies
CONCEPT OF MICROBIOLOGICAL GRAPH OF FEED AND FOOD PRODUCTION
Authors: Iegorov B. , Iegorova А. , Yeryganov К.
Published: October 2024

Compound feeds are favorable environments for microorganisms, namely bacteria and fungi. Both groups contain nonpathogenic, opportunistic and pathogenic members. Bacteria can cause infections, and fungi can cause mycotoxicoses, so controlling microbial contamination of feed is of great importance. Sources of microbial contamination of compound feed include both raw materials and the production environment: air, surfaces, equipment, and the hands and clothing of employees. As raw materials and pre-products move through production lines, they undergo certain processes that can either reduce or increase microbial contamination. The reducing processes include grain dehulling and high-temperature processing (moisture and heat treatment, conditioning, extrusion, expansion, drying of minerals, granulation), while the increasing processes include making preliminary mixtures, grinding, dosing and mixing, and the production of grits. In dosing and mixing, the contribution of each component is determined by its dose and has a two-way effect: the component contributes its microbiota, but its mass dilutes the mixture. The sequence of these processes represents a certain dynamics of microbial burden, which will result in the contamination level of the finished product lower or higher than in the initial raw material. This sequence can be represented as a microbiological graph, the vertices of which are the positive or negative contributions of the processes to the microbiological burden of the material. And the system of such vertices can be represented as a simple mathematical equation. Creating microbiological graphs for individual production lines or for the manufacture as a whole can help to understand the microbiological dynamics in a material or product and apply appropriate corrective measures to prevent microbiological hazards in the final product. This paper proposes a method of making a microbiological graph with two types of vertex designations for the IV generation compound feed production, as well as a mathematical apparatus for calculating the vertices of the graph.
Відповідний квазі-обернений ланцюговий дріб типу Тіле
Authors: Мисло Юлія Михайлівна
Published: October 2024

В статті доведені рекурентні формули знаходження коефіцієнтів відповідного степеневому ряду квазі--оберненого ланцюгового дробу типу Тіле.
On exponential asymptotics of one class of homeomorphisms at a point of the complex plane
Authors: Stefanchuk Mariia Volodymyrivna
Published: October 2024

The presented paper investigates the exponential asymptotics at a point of the complex plane of the ring Q-homeomorphisms with respect to p-modulus for p>2. Examples showing sharpness of the obtained results have been constructed.
Influence of metabolic profile on macro- and microvascular damage in patients with moderate, high and very high cardiovascular risk
Authors: Serezhina E. K. , Obrezan A. A. , Obrezan A. G.
Published: October 2024

Aim. To evaluate the association of the triglyceride-glucose index (TGI) with micro- and macrovascular changes in patients with moderate, high and very high cardiovascular risk (CVR).

Material and methods. The study included 134 men and 129 women aged 40 to 65 years with a SCORE2 ten-year risk of adverse cardiovascular events of 2,5% or more. Based on a detailed survey, a comprehensive physical and paraclinical examination, the relationship between TGI and CVR factors was assessed using Pearson correlation analysis, followed by a linear correlation strength assessment using the Chaddock scale. Modeling of the TGI association with macro- and microvascular damage in patients with moderate CVD was performed using multivariate logistic regression.

Results. According to regression analysis, increased TGI was associated with an increased risk of both macrovascular and microvascular changes. Similar results were obtained using multivariate logistic regression with model adjustment for age, sex, body mass index, waist circumference, smoking, hypertension, family history of premature cardiovascular disease, lipid-lowering therapy, and glucose-lowering therapy. An increased level of TGI was associated with an increase in the odds ratio (OR) of carotid atherosclerosis (OR 1,73, 95% confidence interval 1,27-2,36, P for trend <0,001), an increase in the urine albumin-creatinine ratio (OR 1,61, 95% CI 1,22-2,13, P for trend <0,001) and a decrease in estimated glomerular filtration rate (OR 1,67, 95% CI 1,10-1,50, P for trend =0,02).

Conclusion. TGI is an important and accessible additional risk factor for both micro- and macrovascular damage in everyday clinical practice, regardless of whether the patient has diabetes. For personalized CVR stratification and determination of further management tactics for patients with moderate, high and very high CR, the maximum available factors should be assessed, each of which can influence the disease course, while the summation of the main and additional factors significantly worsens the prognosis.
Electrocardiographic criteria for occlusive and prognostically unfavorable coronary artery disease
Authors: Pereverzeva K. G. , Yakushin S. S. , Dubova N. V.
Published: October 2024

Since patients with occlusive coronary artery thrombosis benefit more from emergency reperfusion, after the widespread introduction of thrombolytic therapy, the concept of Q-wave and non-Q-wave myocardial infarction was replaced by the concept of ST-segment elevation (STE) and non-STE (NSTE) acute coronary syndrome (ACS). But at present, due to the spread of mechanical reperfusion, this concept does not seem to be fully perfect. The electrocardiographic (ECG) diagnostic method allows, among patients with NSTE-ACS, to identify a group of patients with occlusive and/or prognostically unfavorable hemodynamically significant coronary lesions, as well as to provide them with timely percutaneous coronary intervention as early as possible and to improve outcomes. This article rationales changing approaches to the management of patients with NSTE-ACS and analyzes in detail the currently known ECG criteria for occlusive and/or prognostically unfavorable coronary lesions.
Familial combined hyperlipidemia: current status of the problem (literature review)
Authors: Timoshchenko O. V. , Shakhtshneider E. V.
Published: October 2024

Among the various dyslipidemia types, familial combined hyperlipidemia (FCH) is the most common genetic disorder, which is characterized by at least two dif­ferent forms of lipid disorders: hypercholesterolemia and hypertriglyceridemia. In FCH, the risk of atherosclerotic cardiovascular diseases (CVDs), including at a young age, increases significantly. The aim was to analyze literature data on modern criteria for diagnosis, pathogenesis and data from molecular genetic studies of FCH. Future studies aimed at understanding the underlying genetic and metabolic mechanisms of FCH and developing effective treatment strategies should include larger cohort studies with greater genetic diversity, as well as inves­tigation of epigenetic and lifestyle factors.
Peripheral plaque burden in the diagnosis of coronary atherosclerosis in rheumatoid arthritis
Authors: Fomicheva O. A. , Balakhonova T. V. , Pogorelova O. A. , Tripoten M. I. , Shingareeva F. F. , Kuzyakina S. O. , Yarovaya E. B. , Gerasimova E. V. , Popkova T. V. , Karpov Yu. A. , Nassonov E. L.
Published: October 2024

Aim. To assess plaque burden according to peripheral artery ultrasound examination in patients with rheumatoid arthritis (RA) with low and moderate disease activity in comparison with the coronary artery condition.

Material and methods. The study included 64 patients, of which 43 patients with an established diagnosis of RA and 21 patients with coronary artery disease (CAD) without RA (comparison group). All patients underwent a clinical and paraclinical examination to verify myocardial ischemia and/or CAD according to the 2020 national guidelines, as well as a carotid and femoral artery ultrasound (the latter, only for patients with RA) with determination of plaque burden.

Results. In patients with RA in combination with CAD, plaque burden is higher than in patients with RA without coronary artery disease regarding the carotid plaque number 4,0 [4,0; 5,0]/2,0 [1,0; 3,5], proportion of maximum stenosis 35,0 [35,0; 45,0]/30,0 [25,0; 35,0] and the proportion of total stenosis 120,0 [110,0; 152,5]/85,0 [40,0; 110,0]. Three or more carotid plaques determine significant coronary atherosclerosis in RA. In RA patients with CAD, the combination of caro­tid and femoral plaques is associated with significant coronary atherosclerosis in 75% of cases. In a comparative analysis of patients with RA CAD+/RA CAD-, no significant differences were found in the main cardiovascular risk factors, lipid, and inflammatory parameters. When comparing the plaque burden indicators, the severity of coronary atherosclerosis was not revealed between RA patients with CAD+ and the comparison group.

Conclusion. Determining the peripheral plaque burden parameters increases the clinical significance of ultrasound as a stage of non-invasive CAD diagnosis in RA.
Potential of diagnostic electron microscopy of calcification, pathological neovascularization and elastolysis in combination with phenotyping of cell populations in large arteries
Authors: Mukhamadiyarov R. A. , Klyshnikov K. Yu. , Koshelev V. A. , Kutikhin A. G.
Published: October 2024

Aim. To determine the potential of diagnostic electron microscopy of intraplaque processes (severity of lipid damage, fibrous cap thickness and condition, severity of pathological neovascularization, presence, nature and severity of calcification, ratio and distribution of various cell populations).

Material and methods. The study objects were plaques removed during endar­terectomy from the human carotid artery and segments of the human internal mammary artery removed during coronary bypass surgery. Whole specimens were subjected to chemical fixation, staining with heavy metal salts, embedding in epoxy resin followed by layer-by-layer grinding, polishing, contrasting, visualization using back-scattered electron scanning electron microscopy and three-dimensional reconstruction with color mapping (modified EM-BSEM).

Results. The use of a modified EM-BSEM made it possible to: 1) visualize the fibrous cap thickness and assess the extracellular matrix; 2) analyze the neointimal lipid distribution; 3) perform three-dimensional reconstruction and analyze the microenvironment of calcifications of various sizes; 4) visualize endothelial cells, defects in interendothelial contacts and the basement membrane of neointimal capillaries with their subsequent three-dimensional reconstruction; 5) perform an analysis of age-dependent defects in the basement membrane and internal elastic membrane of the internal mammary artery. The resolution of the obtained images was significantly superior to intravascular imaging methods (intravascular ultrasound and optical coherence tomography), allowing additional assessment of capillary fluidity, the degree of calcification encapsulation and the condition of elastic fibers. Three-dimensional reconstruction of calcifications, neointimal capillaries and elastic fibers made it possible to assess their spatial density and heterogeneity. Simultaneously with the identification and assessment of these histological structures, objective phenotyping of cell populations was performed, which made it possible to isolate macrophages and foam cells, vascular smooth muscle cells, fibroblasts and endothelial cells in atherosclerotic plaques and automatically identify them through color mapping determined by their electronic contrast distribution signatures.

Conclusion. The modified EM-BSEM method allows for universal electron microscopic diagnosis of atherosclerotic and elastolytic lesions of large arteries with high information content about vascular remodeling and high accuracy. Electronic contrast distribution signatures unique for each cell population indicate the possibility of their automated phenotyping using specialized neural network algorithms.