bluuebunny/crossref_metadata_2025 huggingface dataset:
Slow Down! Digital Deceleration Towards A Socialist Social Media
Authors: Ranger Jamie
Published: January 2020

Hartmut Rosa argues that three systems of social acceleration (technical acceleration, the acceleration of social change and the acceleration of the pace of life) have emerged as fundamental to the human experience of late modernity. It is here argued that the digital imaginary, specifically curated by the “universal” social media platforms causes what Dominic Pettman has dubbed the “hypermodulation” of the subject, which contributes to the reproduction of the capitalist status quo. Consequently, I here argue that a socialist approach to the digital must commit to what Rosa would term an ideological (oppositional) deceleration to counteract such tendencies.
Towards a Marxist Theory of Mediation: Contributions from Ibero-America to the Study of Digital Communication
Authors: Pedro-Carañana Joan
Published: January 2020

This paper presents and articulates for the first time the concept of mediation as theorised by three key scholars of the Ibero-American space, namely Manuel Martín-Serrano, Luis Martín-Santos, and Jesús Martín-Barbero. This article shows that their understandings of mediation are valuable for the study of digital communication, particularly for identifying criteria that facilitate the sublation of communicative capitalism into communicative socialism. The three scholars have placed the concept of mediation at the centre of their intellectual production with the aim of breaking with mechanical Marxism, but provide differing conceptualisations and have scarcely engaged in a dialogue of knowledges. This article will articulate the complementarity of Martín-Serrano’s Marxist socio-historical analysis of communication, Martín-Barbero’s Latin American cultural studies, and Martín-Santos’s phenomenological theorisation of mediation as the key concept of Marxist epistemology.
Rising With the Robots: Towards a Human-Machine Autonomy for Digital Socialism
Authors: Cox Christopher M
Published: January 2020

This essay is concerned with conceptualising digital socialism in two ways. First, this essay typifies digital socialism as a real utopian project bringing together the utopian potential of “full automation” as tied to socio-economic imperatives indicative of socialist aims. Second, in recognition of a critical gap between full automation and an emerging technological autonomy, this essay argues for a human-machine autonomy that situates autonomy as a shared condition among humans and machines. By conceiving of humans and automated technologies as autonomous subject aligned against capital, pursuing the aims of digital socialism can anticipate and avoid capitalist ideologies that hinders possibilities for autonomous pursuit of digital socialism.
Digital Socialism Beyond the Digital Social: Confronting Communicative Capitalism with Ethics of Care
Authors: Della Ratta Donatella
Published: January 2020

This paper analyses the role of the “social” in communicative capitalism. It shows how the digital social is situated in the context of ideology, exploitation, and alienation. Based on the ethics of care, the essay outlines foundations of an alternative concept and reality of the social in digital socialism. It borrows the key concept of “care” from feminist theory and ethics and uses it to explore alternative paths to rethink “digital socialism” in the age of social media ubiquity and the pervasiveness of communicative capitalism. We need imaginative efforts to think beyond “capitalist realism” as a “pervasive atmosphere” (Fisher 2009, 16) that impacts not just the economy and cultural production, but also the domain of the ideas to the extent that it seems “impossible even to imagine a coherent alternative to it” (Fisher 2009, 2).
Sistem Monitoring Keberadaan Pengunjung Pariwisata Secara Realtime Dengan Metode Wireless Network Clustering
Authors: Taufik Mochammad , Hudiono Hudiono , Rakhmania Amalia Eka , P Ridho Hendra Yoga
Published: January 2020

Di era saat ini, perkembangan teknologi sangat pesat, termasuk di bidang pariwisata. Salah satu hal utama yang menjadi perhatian di bidang pariwisata adalah kenyamanan pengunjung, yang dipengaruhi oleh faktor keamanan, terutama keamanan anak-anak. Masalah yang sering terjadi adalah terpisahnya anak dengan keluarganya di tengah keramaian pengunjung pariwisata. Sistem monitoring yang dapat memantau posisi anak-anak merupakan solusi dari permasalahan ini. Sistem monitoring yang diajukan menggunakan metode wireless network clustering dan terdiri dari perangkat statis node, mobile node danserver. Mobile node merupakan perangkat yang dibawa oleh pengunjung anak-anak yang berfungsi mengirimkan data posisi secara realtime ke statis node menggunakan modul transmisi RF HC-12, sedangkan statis node berfungsi sebagai penangkap pancaran dari mobile node, yang kemudian mengirimkan data pada server untuk kemudian ditampilkan di perangkat android yang dibawa oleh orang tua atau keluarganya. Hasil pengujian menunjukkan bahwa data dapat dikirim dengan optimal ketika pengaturan RF HC-12 menggunakan daya transmisi 20 dBm dan posisi antenna spring vertikal. Statis node dipasang dengan jarak 15 meter satu sama lain, sesuai dengan radius maksimal pengiriman data RF HC-12. Akurasi yang didapat mencapai 92% dengan 1000 kali percobaan pengiriman data.
The Potential Hypoglycemic Activities of Red Onion Extracts in Alloxan-Induced Hyperglycemic Mice
Authors: Makmun Armanto , Syamsu Rachmat Faisal , Jumadil Aisyah , Rabia -
Published: January 2020

Objective: The present study aimed to determine the potential effect of red onion extracts on ameliorating the blood glucose levels in alloxan-induced hyperglycemic mice.Material and Methods:Hyperglicemia was induced by single intramuscular injection of 70 mg/kg body weight of alloxan monohydrate. 24 mice were randomly assigned to four groups of 6 each including alloxan control (group AC), and three alloxan groups treated with doses 25 mg/kg body weight (group AR25), 50 mg/kg body weight (group AR50), and 100 mg/ kg body weight (group AR100) of red onion extracts. The latter three groups were treated with red onion extract for two weeks. The blood glucose levels were measured using a glucometer.Results and Discussion: The different doses of red onion extracts induced the different responses of blood glucose levels in hyperglycemia mice. The main finding of the present study revealed the significant capacity to ameliorate the blood glucose levels were shown in mice treated with 100 mg/kg body weight of red onion extracts (p<0.05).Conclusion: The red onion extracts at 100 mg/kg body weight significantly ameliorated the blood glucose in alloxan-induced hyperglycemic mice.International Journal of Human and Health Sciences Vol. 04 No. 02 April’20 Page : 98-101
Ethanol Extract of Black Sugarcane Decrease Ischemia Volume and Bax Expression In Rats’ Brain
Authors: Handayani Ety Sari , Nur Alfan , Kuswati - , Nugraha Zainuri Sabta , Ikhsani Nastiti Widya , Sakti Faisal Ridho , Akhmad Syaefudin Ali
Published: January 2020

Background:Black sugarcane contains policosanol, quercetin antioxidant and 14-3-3 protein. These compounds are proven in a pre-clinical test of their ability to reduce brain ischemia. There are no pre-clinic test that prove the neuro-protectant act of black sugarcane extract on ischemia-induced rats, and how its mechanism to protect brain is not yet clear. This study’s purpose is to find the effect of ethanol extract of black sugarcane (BSEE) towards brains’ ischemic volume and to find is there any Bax role on the BSEE’s neuroprotectant mechanism.Methods: This study used fifteen male rats (Wistar). The rats were divided into three groups: group A that had been induced with BCCAO and received BSSE (group A), the rats that had been induced with BCCAO (group B), and sham group (group C). BSEE were given for a week, before bilateral ligation of common carotid artery. The BCCAO duration is 20 minutes, reperfusion periods of 2 hours. Rats’ head decapitation is done two hours after ligation. Brain tissues were colored with TTC. Ischemic brain area were analyzed using Image I software. Bax’ expression scoring was done in the brain preparations with immonohistochemical with Anti-Bax antibody. Anti-Bax proteins were anylized using ALLRED Score, while the statistic analyzing was done with One Way ANOVA.Results: There is a difference of ischemia volume’s mean (p=0,018) and bax protein expression (p=0,013) on the rats brain.Conclusion: BSEE is able to reduce ischemia volume and Bax protein expression on the rats’ brain.International Journal of Human and Health Sciences Vol. 04 No. 02 April’20 Page : 102-108
Daily Intake of Advanced Glycation End Products, Fibers and Vitamin C: Their Relationship with Nutrition Status in Adolescent Girls
Authors: Sholichah Rizka M , Hanim Diffah , Indarto Dono
Published: January 2020

Introduction: Eating habits including food choice are responsible formalnutrition problem in Indonesia. For example, fast foods are very popular in adolescent life, especially who lives in urban areas. The objective of this research is to analyze the relationship of daily intake of Advanced Glycation End products (AGEs), fibers and vitamin C with nutrition status in adolescent girls.Methods: This cross sectional study was conducted in 150 adolescent girls of senior high schools who were in grade X and XI in Kediri city, East Java Province. Data of AGEs, fibers and vitamin C intake were determined using a 24h food recall questionnaire for two alternating days.Nutrition status was based on body mass index for age based on the z-score issued by the Indonesian Ministry of Health. The chi square and multiple logistic regression test was used to analyze the relationship of those variables with nutrition status. The significant level was set up at p value < 0.05.Results: The prevalence of overweight and obese was 26% in adolescent girls. Inadequate daily intake of fibers and vitamin C was commonly found in adolescent girls whilst AGEs were highly consumed by adolescent girls. AGEs intake (OR=1.85; 95% CI: 0.88-3.85; p=0.101), fiber intake (OR=0.92; 95% CI: 0.43-1.99; p= 0.839) and vitamin C intake (OR=0.85; 95% CI: 0.36-1.99; p=0.710) were positively related to nutrition status but it was not statistically significant.Discussion: High intake of AGEs and low intake of fiber and vitamin Cincreases the risk of overweight and obese in adolescent girls, compared to those who have low intake of AGEs and high intake of fibers and vitamin C but it was not statistically significant.International Journal of Human and Health Sciences Vol. 04 No. 02 April’20 Page : 109-113
The Asthma Control Test (ACT) as Predictor of Asthma Exacerbation among Indonesian Hajj Pilgrims in 2018
Authors: A Saifuddin , U Zaini Nasir , I Rengganis
Published: January 2020

Objective: Every year, millions of Muslims from around the world gather in Saudi Arabia to perform Hajj. Before leaving for pilgrimage, Indonesian pilgrims go through various health examinations in Regional Primary Health Center (Pusat Kesehatan Masyarakat/ Puskesmas). Since there was no existing research on Asthma Control Test (ACT) assessment for pilgrims with bronchial asthma to predict asthma exacerbations during Hajj pilgrimage period, this cohort study was conducted to fill this gap.Methods: Pilgrims who suffered from asthma were recruited in Daerah Khusus Ibukota (DKI) Jakarta Province region in 2018. The degree classification of asthma in the ACT group was determined as uncontrolled, partially controlled, and fully controlled. ACT scores were calculated in Puskesmas and embarkation. Observation of asthma exacerbations in pilgrims while performing Hajj was performed by doctors. Data were analyzed with SPSS for Windows.Results: A total of 68 participants were included (46 female [67.6%]; 45 aged <60 years [66.2%]). At embarkation, the asthma classification based on the ACT was as follows: 36 (52.9%) and 13 (19.1%) pilgrims had partially controlled and uncontrolled asthma, and 17 (47.2%) and 8 (61.5%) of each group experienced exacerbation, respectively, with p = 0.006 for the ACT values at embarkation. The area under the curve value was 0.717 (95% CI; 0.596-0.838).Conclusion: There was increased asthma exacerbation incidence in the uncontrolled and partially controlled ACT groups at embarkation compared to the fully controlled ACT group. The ACT score was able to predict the occurrence of acute asthma exacerbation during Hajj period.International Journal of Human and Health Sciences Vol. 04 No. 02 April’20 Page : 128-135
Factors Associated with Motivation to Volunteer Among Lecturers in Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Authors: Kamarudin Muhammad Khairul , Jun Nicholas Wong Yew , Rashid Aneesa Abdul , Devaraj Navin Kumar , Shamsuddin Nurainul Hana
Published: January 2020

Introduction: Volunteerism is an act that should be encouraged especially among the medical and health sciences community. In this study the motivation to volunteer among lecturers and its associated factors were assessed.Materials and Methods: This is a cross-sectional questionnaire study involving 91 lecturers who fulfilled the inclusion and exclusion criteria in the Faculty of Medicine and Health Sciences, Universiti Putra Malaysia (FMHS, UPM) between May and July 2018. The Voluntary Function Inventory (VFI) was used to evaluate the motivations to volunteer. It consists of six subscales; values, understanding, social, career, protective, enhancement. Scoring is on a Likert scale of 1 to 7. Higher scores of each subscale indicates higher motivation.Results: The proportion of lecturers who do voluntary work is 85.7%. There were no significant association between the socio-demographic factors and volunteerism. The younger age group had a significant association with “career” subscale (median score = 4.6(IQR =1.8)) compared to the older age group (median score = 3.4(IQR=2.7)) (p=0.047). Female lecturers scored significantly higher for “protective” subscale (median score = 4.6(IQR=19)) compared to male lecturers (median score = 3.8 (IQR=2.6)) (p=0.021). Those who volunteered scored significantly higher for “values” subscale compared to those that didn’t volunteer, with a median scores of 5.9 (IQR= 0.8) and 5.4 (IQR 1.1) respectively, (p=0.027). There were no significant association between ethnicity and the income with other subscales.Conclusion: The motivations to volunteer for “career motive” were higher for the younger lecturers. Female lecturers scored higher for “protective motive.” Lecturers who were volunteers scored higher for “value motives” as compared to those who were non-volunteers.International Journal of Human and Health Sciences Vol. 04 No. 02 April’20 Page : 136-141
Giant Cell Tumor Masquerading as Lateral Meniscus Injury: A Case Report
Authors: Rosdi Muhammad Harith , Ebrahim Rozaiman , Yong Pui San Au , Kalimuthu Mohanakumar , Osman Harmizie
Published: January 2020

Giant cell tumor (GCT) is a benign bone tumor with aggressive characteristics and capacity to metastasize. They are more common in the third decade of life and demonstrate a preference for being located in the epiphyseal region of long bones. They have a high local recurrence rate, which depends on the type of treatment and initial tumor presentation. Early detection of GCT is possible with proper clinical assessment and radiograph. However, due to its rarity, physicians may have neglected the possibility of bone tumor as one of the differential diagnosis for cases referred as “soft tissue injury”.We report a case of a 22-year-old lady who presented with seven-month-history of right knee pain, lateral joint line tenderness and positive McMurray test and initially treated as right lateral meniscus injury. However, the knee pain worsened over time and became persistent despite starting on physiotherapy and home-based-exercises. Upon subsequent visit two months later, she presented with tender bony swelling over the lateral tibial plateau and radiological examination revealed a lytic lesion over her proximal right tibia. Magnetic resonance imaging and histopathology testing confirmed the diagnosis of Giant cell tumor. This case report aims to increase the awareness of possible bone tumors in soft tissue injury cases and highlight the importance of detailed reassessment and reviewing diagnosis during each follow up.International Journal of Human and Health Sciences Vol. 04 No. 02 April’20 Page : 148-151
ELABORAÇÃO DE HOLOGRAMA PARA O ENSINO DE GEOMETRIA MOLECULAR
Authors: Lima José Ossian Gadelha de , De Almeida Glaylton Batista
Published: January 2020

Uma das dificuldades enfrentadas no processo de ensino e aprendizagem da Química se refere à abordagem dos conteúdos relacionados ao mundo submicroscópico (atômico e molecular), os quais são difíceis de serem compreendidos pelos alunos. Um exemplo é a Geometria Molecular, conteúdo que exige habilidades visuoespaciais do estudante para entender a disposição das moléculas no espaço e, consequentemente, muitas de suas propriedades químicas e físicas. Nessa perspectiva, o objetivo desse trabalho foi apresentar o processo de elaboração de um produtor educacional (holograma), desenvolvido a partir de materiais simples (capa de CDs, cola, faca de mesa, tablete, etc.), que pode ser utilizado como recurso didático nas aulas de Geometria Molecular, possibilitando aos alunos uma melhor compreensão sobre o formato espacial das estruturas moleculares. Assim, a partir de depoimentos de alunos do primeiro ano do Ensino Médio, após uma aula com apresentação de um holograma elaborado com a molécula de CO2, foi possível perceber uma melhora significativa no entendimento desses estudantes sobre a disposição das moléculas no espaço.

 

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Pengaruh Pemahaman Materi Aqidah Ibadah Terhadap Prilaku Religiusitas Siswa SMK Muhammadiyah Magelang
Authors: Widodo Widodo
Published: January 2020

This study aims to determine the understanding of religious aqeedah material of Magelang Muhammadiyah Vocational High School students, the religious behavior of Magelang Muhammadiyah Vocational High School students, and the influence of the understanding of religious aqidah material on religious grade XI students of SMK Muhammadiyah Magelang. The study was conducted at SMK Muhammadiyah Magelang by taking respondents from class XI as many as 45 students from 130 students there. The methods used are quantitative methods, questionnaire methods and simple linear regression data analysis. The results of the study, the influence of understanding of religious aqeedah of students of SMK Muhammadiyah by 100% categorized in high level, behavior of Students of Muhammadiyah Vocational School Magelang which is 84.4% categorized in moderate level, and there are differences in understanding of religious aqidah worship material on the religious behavior of class XI students in Vocational High Schools (SMK) Muhammadiyah Magelang, obtained an F value of 34.4 and sig. of 0.020 which means that there is a significant influence between the variables "understanding of the material of religious beliefs" on the variable "Student religiosity" because of the value of sig. <0.05. The coefficient of determination (R Square) was obtained at 0.800, which means that the magnitude of the influence of the variable understanding of religious worship material on student religiosity was 80.0%, the rest 20.0% influenced by other variables outside the study.
Filantropi Pendidikan Islam Dalam Peningkatan Motivasi dan Prestasi Siswa di Pondok Pesantren Al-Hikmah Gunung Kidul
Authors: Kholifah Siti
Published: January 2020

This study aims to determine the type of educational scholarships from philanthropic funds in Al-Hikmah Islamic boarding school, the motivation of Al-Hikmah Islamic boarding school students who donated from philanthropic funds, and to determine the achievements of Al-Hikmah Islamic Boarding School donated from philanthropic funds . This research is in the form of qualitative research and uses a quantitative descriptive approach, while the collection of data using techniques, questionnaires, observations, interviews, and documentation. The conclusion of this study is the education philanthropy fund Al-Hikmah Islamic boarding school was obtained from several aspects including; permanent donors, non-permanent donors, government agencies, syahriyyah wali santri, infaq and community sadaqoh. Islamic education philanthropy at Al-Hikmah Islamic boarding school gives a "good" effect on increasing student motivation and achievement, reaching 83.05%. Islamic education philanthropy at Al-Hikmah Islamic boarding school has a quite varied influence on indicators per variable, which is that almost 70% of free school fees can increase student motivation, and 30% can improve student achievement.
Analisis Tentang Penerapan Kurikulum 2013 Pada Mata Pelajaran Aqidah Akhlak
Authors: Mukni'ah Mukni'ah
Published: January 2020

Curriculum is an important part of the implementation of learning in school.  It covers the   aspects of planning, implementation, and evaluation of learning. This study aims to describe the problems of planning, implementing, and evaluating the 2013 curriculum in the subjects of Aqidah Akhlak in MTs. Negeri 04 Jember. The method used in this study is descriptive qualitative with the type of field research.  The data collection method used observation, interviews, and documentation. Data analysis used qualitative descriptive analysis of interactive models of Miles and Huberman. The results showed that the problems in planning, learning, and evaluating the 2013 curriculum in the Aqeedah Akhlak subjects were the difficulties faced by teachers in developing lesson plans and determining learning methods, mismatches between lesson plans and learning implementation, and constructing the score rubrics for attitude assessment.
Pelatihan Penulisan Karya Ilmiah untuk Meningkatkan Kemampuan Guru di SMP Negeri 7 Kota Bengkulu
Authors: Hiasa Fina , Canrhas Amril
Published: January 2020

The purpose of this service is to improve the ability of teachers at SMPN 7 Bengkulu City in writing scientific papers. The method used in this pegabdian activity is a training method by way of lectures and direct demonstrations for trainees. Participants in this activity were the board of teachers of SMP Negeri 7 Bengkulu City, totaling 13 people. The instrument used in this training was a questionnaire that was distributed to participants before and after the training to see whether or not there was an increase in the knowledge of the trainees. This training resulted in an increase in teacher knowledge about scientific work, namely knowledge of reference lists and publication journals by 55%, structure knowledge of scientific works by 40%, technical knowledge of writing scientific papers by 50%, and psychological and economic constraints by 50%.
Within the Whole Body
Authors: Neely Sol , Hope Ishmael , Geiger Will
Published: January 2020

On a cold, snowy January night in Juneau, Alaska, Will Geiger and I convened at Ishmael Hope’s home—with his wife, Lily, and their five children—for dinner and cordiality in advance of our recording session. The Hope family is exceedingly generous with their time and knowledge, and, as is the case whenever we gather at the Hope home, one can palpably discern the multigenerational inspirations and relations that sustain their work, artistry, and community involvement. Once the children went to bed, we dimmed the lights and pulled out our books.

When the editors of Screen Bodies told me that the journal was interested in expanding notions of screen beyond cinema, I inquired about the possibility of interviewing Ishmael Hope and others on Tlingit house screens and, by a kind of phenomenological appeal, of focusing the conversation through a concern for embodiment. Originally, Ishmael and I invited Will Geiger and Forest Haven, a brilliant Tsimshian PhD candidate from University of California, Irvine, to participate, but Forest was unfortunately unable to attend. Over the years, I have worked closely with these three on a number of academic projects, developing a tight and trusted friendship sustained by mutual respect and interwoven eruditions.
Biased Render
Authors: Miner Joshua D.
Published: January 2020

This article explores the digitality of Indigenous bodies within contemporary 3D video games by mainstream and Indigenous developers. Its analysis relies on a critical examination of digital image synthesis via real-time graphics rendering, which algorithmically generates the visible world onscreen from 3D geometries by mapping textures, generating light and shadow, and simulating perceptual phenomena. At a time when physically based, unbiased rendering methods have made photorealistic styles and open-world structures common across AAA games in general, Indigenous game designers have instead employed simplified “low res” styles. Using bias as an interpretive model, this article unpacks how these designers critique mainstream rendering as a cultural-computational practice whose processes are encoded with cultural biases
that frame the relation of player and screen body (avatar). The algorithmic production of digitally modeled bodies, as an essential but masked element of video games, offers a territory where Indigenous developers claim aesthetic presence in the medium.
Unsettling Monstrosity in Rhymes for Young Ghouls
Authors: Neely Sol
Published: January 2020

Rhymes for Young Ghouls (2014), written and directed by Mi’kmaq filmmaker Jeff Barnaby, is primarily presented as a residential school “revenge fantasy.” Some critics and reviewers of the film value it for its pedagogical possibilities, arguing that the film occasions opportunity for dialogue between Indigenous and non-Indigenous audiences about the legacies of the residential school system. Yet, numerous decolonial scholars and activists understand that dialogue alone cannot effect the quality of decolonial justice needed in the wake of genocide. This article approaches the film as a saturated phenomenon and examines the kinds of radical phenomenological transformation that must occur, especially among non-Indigenous audiences, for decolonial imperatives to become legible. Beyond developing a more comprehensive historical panorama of the violence and legacies of the residential school system, this article calls for a kind of translation of experience occasioned by the film, one that dramatically subverts and transforms modalities of consciousness on which coloniality is predicated.
Życie gospodarczo-społeczne w klasztorach w Afryce Północnej w świetle wybranych pism św. Augustyna
Authors: Kołosowski Tadeusz
Published: January 2020

Artykuł przedstawia na tle działalności monastycznej Augustyna i w świetle jego wybranych pism zagadnienia dotyczące życia gospodarczego i społecznego w klasztorach w Afryce Rzymskiej. Autor przedstawia rolę Augustyna w rozwoju cenobityzmu w Afryce Północnej, strukturę społeczną klasztorów, miejsce i rolę pracy w życiu cenobitów duchownych i świeckich oraz kwestie własności i zarządzania majątkiem klasztornym.
Алгоритм доклинической диагностики сахарного диабета 1-го типа как основа для создания Реестра ДААт-позитивных детей и подростков Украины с прогнозированным развитием заболевания
Authors: Tron’ko M.D. , Zak K.P. , Popova V.V.
Published: January 2020

Aim — The establishment of mechanisms for T1D development at early and late preclinical stages of disease formation in children and adolescents. Material and methods. At the State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism of NAMS of Ukraine» mentioned the Program «Immunity in the preclinical period of T1D development» was initiated, on the basis of which the Register of marker-positive children with predictable development of type 1 diabetes was created, which includes 612 children aged from 7 to 15 years with burdened heredity, in which the titer of diabetes-associated autobodies (DAA), cytokines, levels of basal and postprandial glycemia and secretion of C-peptide at preclinical and clinical stages of T1D development in children and adolescents based on the performed clinical and immunological study. Results. The new data have been obtained at the State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism of NAMS of Ukraine», which allowed to substantially supplement the existing ideas about the type 1 diabetes (T1D) pathogenesis. As a result of the performed study, a group of marker-positive children with burdened heredity and a predicted risk of developing the disease was formed. It was found that an increased titer of DAA was observed in 162 (35.45%) of 457 children with burdened heredity with no less than two times determination of DAA presence in them, mainly GADA and IA‑2A, the clinical debut was manifested in 86 (53.08%) of them from 6 months to 16 years (27.4±4.3 months). The formula of combined occurrence and values of simultaneously increased DAA titers to islet autoantigens, namely IA‑2A + GADA, was determined, which is a predictor of both the duration of preclinical stage of T1D development and the debut rate. Impaired cytokine production (increase of the level of proinflammatory cytokines IL‑1α, IL‑6 and TNFα, IL‑8 and IL‑16 while reducing the concentration of IL‑4 in the PB) as key factors of the T1D pathogenesis, which determine the rate of T1D debut, and the aggressiveness of its course were also established. It was found that the early preclinical period of T1D development in DAA+ children was characterized by the presence of dysglycemia in the form of increased glycemia in 2 hour after the glucose tolerance test and a slight decrease in secretion of stimulated C-peptide; in addition, dysglycemia in the form of impaired fasting glycemia was added in DAA+children in the late preclinical period, and a decrease in both basal and stimulated secretion of the C-peptide was determined, indicating that the potential of pancreatic beta cells was depleted.
Рівень циркулюючих імунних комплексів у хворих на дифузний токсичний зоб за умов лікування радіойодом
Authors: Stepura N.M. , Zamotayeva G.A , Volynets I.P.
Published: January 2020

Дифузний токсичний зоб — автоімунне захворювання, обов’язковими ознаками якого є стійка підвищена продукція тиреоїдних гормонів і дифузне збільшення щитоподібної залози (ЩЗ) різного ступеня. Причинами розвитку дифузного токсичного зоба (ДТЗ) є автоімунні процеси, тобто формування агресії антитіл проти тканини власної ЩЗ. Мета роботи — визначення впливу радіойодотерапії на вміст циркулюючих імунних комплексів (ЦІК) у хворих на тиреотоксикоз. Матеріал і методи. Визначали кількість ЦІК у 34 хворих на ДТЗ (хворобу Грейвса) та в 49 пацієнтів із тиреоїдний раком (група порівняння). Вимірювали рівні ЦІК напередодні, через 6 днів, 1 і 6 місяців після введення радіойоду. Результати. У пацієнтів із тиреотоксикозом після введення йоду‑131 кількість ЦІК протягом усього періоду обстеження практично не змінювалась. У хворих на рак ЩЗ введення лікувальних активностей йоду‑131 спричинило зростання вмісту ЦІК із максимальним рівнем через 1 місяць після введення. Висновки. Різниця вмісту ЦІК після радіойодотерапії у хворих на ДТЗ і тиреоїдний рак, вочевидь, є наслідком введення різних доз йоду‑131: хворі з тиреотоксикозом отримували радіойод, активність якого була в межах від 380 МБк до 784 МБк, тоді як активність йоду‑131 у хворих на рак ЩЗ була значно більшою — від 2640 МБк до 6000 МБк.
Об основоположниках эндокринной хирургии. Профессор О.В. Николаев и его школа
Authors: Rybakov S.I.
Published: January 2020

В последние десятилетия наблюдается тенденция присваивать титул «основоположник» той или иной отрасли науки, направления в медицине ученым и практикам, достигшим определенных успехов в этих областях. В частности в хирургии это могут быть впервые выполненные операции при каком-либо заболевании, новый взгляд на патогенез определенной формы патологии и пр. Толкуется это понятие довольно широко и не всегда однозначно. В одном из наиболее авторитетных изданий, 4-томном Толковом словаре русского языка Д.Н. Ушакова, этот термин определяется так: «Основоположник — основатель, создатель какого-нибудь учения, теории, направления, школы». Подобные формулировки содержатся еще в ряде словарей и справочников.
Масса миокарда левого желудочка и ее связь с вариабельностью ритма сердца у пациентов с церебральным атеросклерозом и сахарным диабетом 2-го типа
Authors: Egorova M.S.
Published: January 2020

Вопросы взаимосвязи кардиальной и церебральной патологии вызывают несомненный интерес у врачей различных специальностей, динамично расширяясь. Цель работы — выявить взаимосвязи между массой миокарда левого желудочка (ММЛЖ) и показателями вариабельности ритма сердца (ВРС) у пациентов с церебральным атеросклерозом (ЦА) 1-3-й стадий, в т. ч. и с сахарным диабетом 2-го типа (СД2). Материал и методы. В комплексном клинико-инструментальном исследовании приняли участие 229 пациентов с ЦА 1-3-й степени. Пациентов распределили на 2 группы: І — с ЦА 1-2-й степени (без ишемического инсульта — группа сравнения); ІI — общая группа пациентов, перенесших ишемический атеротромботический инсульт (ИИ). Результаты. Сравниваемые группы статистически значимо различались по показателям толщины стенок левого желудочка (ЛЖ). Так, значения минимальной толщины межжелудочковой перегородки (МЖП) и задней стенки ЛЖ (ЗСЛЖ) были в группе пациентов с ЦА в 1,18 раза и 1,17 раза меньше соответственно по сравнению с показателями группы пациентов с ИИ. Для выявления взаимосвязей проведен корреляционный анализ с расчетом коэффициента ранговой корреляции Спирмена. В общей группе пациентов, перенесших ИИ, установлена только обратная корреляционная связь между показателями ММЛЖ и НЧ/ВЧ% (r= –0,30), а в группе пациентов без ИИ с ЦА 1-2-й стадии связейустановлено не было. Выводы. У пациентов с ЦА 1-2-й степени и СД2 толщина МЖП и ЗСЛЖ достоверно меньше, а концентрический недилатационный тип ремоделирования ЛЖ встречается значимо чаще по сравнению с пациентами, перенесшими ИИ, что свидетельствует прежде всего о том, что перенесенный инсульт самостоятельно не является предиктором последующих кардиоваскулярных событий. Наличие обратной корреляционной связи между ММЛЖ и соотношением симпатической/парасимпатической компонент ВРС у постинсультных пациентов с СД2 и отсутствие таковой у пациентов с начальными проявлениями ЦА и СД2 свидетельствует о более выраженных физиологических взаимосвязях и менее выраженной автономии вегетативной нервной системы после значимого кардиоваскулярного события у пациентов с проявлениями ЦА.
Ультразвукові та цитологічні характеристики радіойодчутливості метастазів папілярного раку щитоподібної залози
Authors: Zelinskaya G.V. , Shelkovoy E.A.
Published: January 2020

Мета — дослідження ультразвукових і цитологічних характеристик метастазів, виявлених у поопераційний період, залежно від їх йоднакопичувальної здатності. Матеріал і методи. Ультразвукові, цитологічні, імуноцитохімічні дослідження проводили на групі метастазів папілярного раку щитоподібної залози, виявлених у поопераційний період (після тиреоїдектомії та радіойодтерапії): 30 радіойодчутливих метастазів і 65 радіойодрезистентних. Оцінювали такі ультразвукові характеристики, як локалізація метастазів, чи є вони множинними або поодинокими, ехогенність, ехоструктуру та наявність гіперехогенних включень. Цитологічні та імуноцитохімічні дослідження проводили на пункційному матеріалі даних метастазів, забарвленому за Романовським. Використовували непрямий імунопероксидазний метод із моноклональними антитілами до тиреоїдної пероксидази та тиреоглобуліну. Статистичний аналіз проводили за непараметричним критерієм Манна – Уїтні та методом χ2 у програмі Statistica 11.0. Результати. Проведені дослідження ультразвукових і цитологічних характеристик поопераційних метастазів папілярних карцином щитоподібної залози не виявили значущої різниці між групами радіойодрезистентних і радіойодчутливих метастазів за такими ультразвуковими характеристиками, як ехогенність, ехоструктура та наявність гіперехогенних включень. Показано, що у випадках виявлення гіпоехогенних метастазіву латеральних лімфатичних колекторах імовірність радіойодрезистентності метастазів становить 93±2%. Ультразвукову ознаку кістозної дегенерації виявляли в 1,8 раза частіше в радіойодрезистентних метастазах порівняно з радіойодчутливими. Цитологічні дослідження демонструють фенотипову гетерогенность епітелію радіойодрезистентних метастазів порівняно з радіойодчутливими та вірогідну різницю в експресії тиреоглобуліну й тиреоїдної пероксидази. Висновки. За даними ультразвукового дослідження не виявлено достовірних змін, які дозволили б проводити диференційну діагностику між радіойодрезистентними та радіойодчутливими метастазами папілярного раку щитоподібної залози. Визначено цитологічні ознаки радіойодрезистентних метастазів папілярного тиреоїдного раку, які дозволяють їх передопераційне прогнозування. Продемонстровано значущу редукцію експресії тиреоїдної пероксидази та тиреоглобуліну в пунктатах радіойодрезистентних метастазів порівняно з радіойодчутливими, що є підставою передопераційного прогнозування радіойодрезистентності поопераційних метастазів папілярного тиреоїдного раку. Виявлені за даними ультразвукової діагностики метастатичні лимфатичні вузли шиї дозволяють проводити подальші імуноцитохімічні та цитологічні дослідження, що може підвищити ефективність діагностики метастазів високодиференційованого раку щитоподібної залози й полегшити вибір подальшого лікування.
Частота депресивних станів у пацієнтів із цукровим діабетом 2-го типу
Authors: Shevchuk М.V. , Tsiganenko O.О. , Taranenko O.V. , Kryzhevsky V.V. , Mankovsky B.M.
Published: January 2020

Психічні розлади входять до численних ускладнень у хворих на цукровий діабет (ЦД), які значною мірою погіршують його перебіг. У статті наведено дані міжнародного дослідження та результати, отримані серед пацієнтів України. Мета роботи — вивчити частоту депресивних станів у хворих на ЦД 2-го типу (ЦД2), ґрунтуючись на результатах проведеного дослідження. Матеріал і методи. Для проведення даного спостереження було рандомізовано 190 пацієнтів відповідно до протоколу міжнародного проспективного дослідження International Prevalence and Treatment of Diabetes and Depression (INTERPRET-DD). Діагностичними інструментами були адаптовані шкали PHQ‑9, PAID, WHO, MINI‑6, Гамільтона; вимірювання рівня HbA1с, ліпідограми; опрацьовані дані з амбулаторних карт пацієнтів за останні 15 років, збирання анамнезу, проведення загального огляду; консультативні висновки психіатра, ендокринолога, хірурга кабінету діабетичної стопи. На підставі отриманих результатів вирішували питання про доцільність тактики лікування за допомогою заспокійливих, антидепресантів, протитривожних засобів і сеансів психотерапії. Результати. Частка чоловіків у дослідженні становила 39,47%, середня тривалість ЦД2 — 9,3±1,2 року. Депресивні розлади діагностовано в 10,7% пацієнтів, за результатами тестування за шкалою PHQ‑9 (Patient Health Questionnaire) у 12,10% випадків відзначено наявність депресивної симптоматики різного ступеня (рівень PHQ>9). Таким пацієнтам було рекомендовано проведення сеансів психотерапії, медикаментозне лікування антидепресантами та прицільне спостереження психіатром протягом подальшого року. Висновки. Визначено частоту депресивних розладів у пацієнтів із ЦД2.
Small model languages as tools for reflection
Authors: Rastall Paul
Published: January 2020

The paper presents a way of investigating verbal communication and examining assumptions about it independently of particular approaches to linguistic analysis through the development of imaginary language systems using very limited models (small model languages), identifying limitations, and finding ways to extend them. The imaginary systems are compared to real verbal phenomena to highlight communicational principles and show where questions arise. They can be pedagogical tools. A simple model is introduced as an example and ways of extending it are considered along with the questions that are raised in the process.
Pragmatism as ventriloquism: Creating a dialogue among seven traditions in the study of communication
Authors: Cooren François
Published: January 2020

In this article, I propose to respond to Craig’s (1999) call for a dialogue between what he identified as the seven traditions in the study of communication, as well as Russill’s (2005) positioning of pragmatism as a meta-perspective on the seven others. I show that a way to respond to Craig and Russill consists of considering communication as an activity of ventriloquism, a thesis that is, as I demonstrate, congruent with the pragmatist meta-tradition. Communicating and experiencing the world, according to the pragmatist view, indeed amounts to responding or reacting to what one considers a situation requires, demands or requests, which is precisely what a ventriloqual view tries to analyze and unveil. I then introduce a dialogue between this ventriloqual view of pragmatism and the seven traditions that Craig identified.
Genetic clustering algorithm
Authors: Anfyorov M. A.
Published: January 2020

The genetic algorithm of clustering of analysis objects in different data domains has been offered within the hybrid concept of intelligent information technologies development aimed to support decision-making. The algorithm makes it possible to account for different preferences of the analyst in clustering reflected in a calculation formula of fitness function. The place of this algorithm among those used for cluster analysis has been shown. The algorithm is simple in its program implementation, which increases its usage reliability. The used technology of evolutionary modeling is rather expanded in the mentioned algorithm. Firstly, the decimal chromosomes coding is used instead of the traditional binary coding. This has resulted from the fact that the chromosome genes condition is multiple and not binary. Moreover, this is due to the absence of the genetic operator of inversion in this algorithm. Secondly, a new genetic operator used for filtering has been implemented. This operator eliminates chromosomes that do not meet the required clusters quantity condition in a task. Such chromosomes can appear in the stochastic process of their evolution. The presented algorithm has been studied in a series of simulation experiments. As a result, it has been found that stabilization of splitting into clusters is reached when the number of completed generations of evolution is 200 and more, and the population size is rather small: from 150 chromosomes (in this case no considerable amount of random-access store is required). The calculations carried out on real data showed for this algorithm the high quality of clustering and the acceptable computing speed of the same order with the computing speed of SOM and “k-means” algorithms.
Rancang Bangun Sistem Informasi Penggajian Pegawai Berbasis Web di Madrasah Ibtidaiyah Nurul Huda Kota Tangerang
Authors: Taufiq Rohmat , Ummah Risma Rohmatul , Nasrullah Irfan , Permana Angga Aditya
Published: January 2020

Madrasah Ibtidaiyah Nurul Huda Kota Tangerang is one of the private schools, but data processing payroll in this schooll was still unintegrated. The ongoing payroll system was still in use of a manual system. The results of this were many obstacles faced by the school in the production of materials such as in payroll contracts, payroll calculations, payroll slips, and drawing up payroll reports. Also, the information presentation was less fast, inexact, inaccurate because current media transmission information consists of purely physical documents. The research method used waterfall method. Waterfall is a model of its development process for the coverage of a system, sequential or linear. The research steps were divided into: analysis, design, coding, testing and maintenance. The system would then be built using synthetic programming language PHP and Mysql as a database. The web-based employee payroll information system was intended to provide advantages in payroll data processing such as payroll process, payroll calculations, payroll slips, and payroll reports, so that manual jobs could be much easier and computerized. The result was derived from this research was development of the web-based employee payroll information system.
Peculiarities of Representation in Civil Proceedings
Authors: Rezvorovych K. R.
Published: January 2020

The thesis was devoted to the research of the peculiarities of representation in the civil process. The main objective of this thesis is the determination of the peculiarities of legal adjusting for the representation in the civil process. Methodological basis of the thesis consisted of such methods as: formal-logical, system analysis, dialectical and hermeneutical. The relevance of this thesis is evidenced in particular by there that was disclosed such facts as: the content of the institute of representation in civil law and civil process doctrine; the circle of persons who can be representatives in civil procedure. It was made a systematic analysis of the provisions of the Civil Procedure Code (CPC) of Ukraine on the subject of the implementation of the representation of individuals in civil proceedings. There were investigated the problems of restricting the circle of persons who can be representatives in civil proceedings. The analysis of standing and its confirmation by various persons who can carry out representation in civil proceedings was done. According to the results of the research, it was established that modern CPC of Ukraine does not determine the essence of relations between representatives and persons whose interests they realize. The mainstreaming and law-governing influence is mainly related to the legal personality of the representatives, their procedural status. It was also determined the range of duties and rights of representatives within the civil legal process. In addition, it was proved that the modern CPC of Ukraine is being introduced in the state, in fact, a monopoly on the representation of the parties by a lawyer in the courts, in the civil process, but leaves the possibility of realizing the relations of representation between an individual and another person who does not have the lawyer status, who ruled only in, such cold as, minor affairs. Thus, the practical significance of the conclusions reached was aimed primarily at the theoretical and methodological plane to continue the reform of the institution of representation in the civil process, as well as in the practical activities of representatives in the context of expanding the opportunities for individuals to exercise their procedure’s rights.