bluuebunny/crossref_metadata_2025 huggingface dataset:
The challenges of developing and identifying a pipeline for drug development for Aspergillus fumigatus-induced lung infections
Authors: Zhao Yuyao
Published: December 2023

Aspergillosis, a lung infection brought on by Aspergillus, is particularly dangerous for people with impaired immune systems. Aspergillosis is difficult to prevent since the spores are found in the environment on a regular basis. Healthy people are usually unaffected, but those with compromised immune systems must deal with the challenges of medication resistance and reinfection throughout therapy. Additionally, Aspergillus fumigatus is listed as a fungal priority pathogen by the World Health Organization. To tackle this developing pandemic and improve outcomes for those afflicted, effective management measures and further research are required. This paper analyses the challenges faced in the drug pipeline against Aspergillus fumigatus, so as to address the spread of the disease of Aspergillosis lung infections. Recognizing these challenges could help researchers consider other possible modes of treatment and what to look out for. The paper proposes that a possibility could be a combination of various drugs, along with immunotherapy, in order to tackle the disease effectively. This means that continued research and efforts are still needed in the drug development pipeline for Aspergillus fumigatus, preferably with more funding. The threat it poses is significant, as its increased infection rate suggests it has the potential to become an epidemic in the next 50 years. Thus, a breakthrough would be significant in ensuring higher survival rates among patients.
Review of the effects of chronic stress on human insomnia
Authors: Kang Leyi
Published: December 2023

While there are decent amounts of studies exploring the effects of chronic stress on sleep in animal models (e.g., rats), studies recruiting human subjects on this specific topic are rare in neuroscience and psychology. Thus, this paper aims to review the literature focusing on and mentioning chronic stress effects on human sleep, primarily based on experimental trials and clinical cases. Specifically, this review assesses the relationship between chronic stress (rather than acute stress and traumatic events) and insomnia in adult humans, the neurological and behavioral influence of chronic stress, and potential treatments for insomnia related to stress. The review was conducted using the PsycInfo database. Results from the reviewed literature show that chronic stress is associated with a decrease in neurogenesis and can be predicted by amygdala reactivity. Human subjects are likely to replicate results from rat models that show a decrease in REM sleep time under chronic stress and altered slow wave activities during sleep, and such deprivation of REM sleep can further alter hormonal levels in brain areas relating to stress and learning. Promisingly, there is evidence supporting the efficacy of cognitive and behavioral therapy for insomnia (CBT-I), conducted by professional therapists.
Application of CRISPR/Cas system in rice
Authors: Jiang Ruihang , Liu Yansen , Wang Shiting
Published: December 2023

Rice, as an essential food in human life, is in increasing demand for food in today's society with such a large population. CRISPR, as the most popular gene editing system at present, has the characteristics of precision, low cost, and simple operation, so it is able to modify the genes of rice to a large extent in order to control its traits and cultivate excellent varieties. In order to better address the demand for food in society, this article conducts gene editing on rice from the perspective of using the CRISPR/Cas system. It provides a brief introduction to the relevant genes and control methods for controlling rice yield in current scientific research achievements, as well as a specific explanation of the relevant genes and control methods for stress resistance such as salt tolerance, cold resistance, and disease resistance. At the same time, in addition to the summary of the current research status, suggestions and prospects are also put forward for the shortcomings of the CRISPR/Cas system in the application of rice and other plants so far.
HIF-1 as a possible therapy for Alzheimer's disease
Authors: Liu Puran
Published: December 2023

The most significant pathology markers of Alzheimer's Disease (AD) are the tau protein and amyloid beta protein (A). A transcription factor called hypoxia-induced factor 1 (HIF-1) is in charge of helping cells and tissues adjust to low oxygen levels. Recent research points to HIF-1 as a possible therapeutic target for neurodegenerative disorders. On the one hand, it is hypothesized that HIF-1 causes neuroinflammation, which aids in the development of AD, by activating -secretase and inhibiting -secretases, thereby increasing the processing of APP and the production of A. HIF-1, on the other hand, is able to fend off the harmful effects of A and stop tau protein from becoming hyperphosphorylated. Icariin has numerous pharmacological actions as a medication that can decrease the clinical indicators of AD, including anti-depression, treatment of ischemic brain injury, anti-dementia, anti-aging, etc., and is closely related to HIF-1. This article reviews the possible role of HIF-1 in the pathogenesis of AD and its future prospects.
A brief introduction and the clinical meaning of Nrf2-Keap1 pathway
Authors: Kong Qikai , Li Xinmeng , Zhu Zhiyuan
Published: December 2023

In a normal physiological state, Nrf2-Keap1 pathway is associated with antioxidation progress. Mostly, Nrf2 interacts with Keap1 and shows a low cellular abundance. When the intracellular oxidative stress level increases, Nrf2 uncouples with Keap1 then performs nuclear translocation to regulate the RNA levels of its downstream targets, control the redox-related balance in the cell and exert cytoprotective effect. The mutation of related factors in the signal pathway will lead to the abnormality of oxidative damage, which may lead to lung cancer. Therefore, the remission treatment of lung cancer can be achieved through the inhibition of Nrf2-Keap1pathway. We will concentrate on Nrf2 and Keap1's structural and functional domains in the review. Then we summary the mutation sites and signal pathway of Nrf2-Keap1. Most importantly, we discuss the potential clinical application of Nrf2-Keap1 and further adopt the method of molecular docking to screen the small molecules acting on Nrf2-Keap1 to provide the potential improvement to current lung cancer treatment.
The influences of smoking on the formation of Atherosclerosis
Authors: Diao Kangteng
Published: December 2023

Smoking is closely related to the occurrence and development of many other cardio cerebral Vascular diseases. Smoking can increase the risk of moderate diseases such as hypertension, coronary heart disease, myocardial infarction, and stroke. Smoking will cause Vasoconstriction, increase the load of the heart, lead to poor blood circulation, and then lead to the occurrence of cardio cerebral Vascular disease. In addition, smoking can also have adverse effects on the human immune system. Smoking can lead to a decrease in immune function and increase the risk of infections. Research shows that smokers are more likely to suffer from upper respiratory tract infection, pneumonia and other diseases. Smoking can also cause pulmonary inflammatory reactions, leading to airway stenosis and obstruction, seriously affecting respiratory function. Studying the role of smoking in promoting the formation of Atherosclerosis has important scientific and social significance, which helps to understand the relationship between smoking and Atherosclerosis, provides scientific basis and guidance, promotes health publicity and education, and improves public health.
Interfering the inter-spine competition using cadherin/catenin complex as a potential treatment in ASDs
Authors: Yang Xixi
Published: December 2023

Autism, a type of genetic disease, was found to be related to various gene mutations like SHANK 3 and SHANK2. The direct results are deficits in spine pruning in early childhood while prunings frequency is lower than usual. In this essay, we investigate a potential treatment for genetic disease by adjusting a type of complexcadherin/catenin complex, which is a complex that might be able to reverse the effect of spine pruning loss. A specific experiment was designed to fulfill our purpose. The significance of this work is that it sheds light on a possible treatment for an innate genetic disease. However, all of the methods mentioned are theoretical, requiring further implementation.
Application of lateral flow immunochromatography assay, CRISPR/Cas12, and QDs-based biosensing for SARS-CoV-2 diagnosis
Authors: Lai Meng Si Theresa
Published: December 2023

During the COVID-19 pandemic, scientists have developed many diagnostic techniques, such as biosensors, to detect whether a patient is infected by SARS-CoV-2. This could help the governments to plan an effective method to decrease the rate at which the illness is spreading across the globe. These diagnostic techniques are developed after the research of this foreign viral pathogen, SARS-CoV-2, by investigating the potential analytes that could be used and the various ways that the virus could infect a person after exposure. The three diagnostic techniques will be discussed in this paper, including lateral flow immunochromatography assay (LFIA), CRISPR/Cas12, and quantum dots (QDs)-based biosensing system. In addition, this research will also systematically discuss the advantages and disadvantages of these three monitoring and analysis methods. Although these three diagnostic techniques have very high selectivity and sensitivity, establishing a reliable result, there are pathogens that could result in similar symptoms of respiratory pneumonia just like SARS-CoV-2. The diagnostic techniques explained in this paper cant diagnose more than one pathogen or disease, therefore, it is essential to further develop a multiplexing assay to produce a more detailed result.
Application of biosensors in the detection of plant biomolecules
Authors: Lin Xufan
Published: December 2023

Traditional plant research mainly relies on the observation of external
performance, and it is difficult to accurately understand the internal physiological and environmental responses of plants. However, the introduction of biosensors provides different avenues to address these issues. The application of biosensors in plants is an emerging field, combining sensor technology with biology, bringing new opportunities for plant research and agricultural production. The core content of plant biosensing technology is to embed biosensors into plants to monitor and transmit information such as biomolecules, metabolites, or environmental factors inside plants. This paper introduces the design of biosensors, the research progress of biosensors, and the development trend of biosensors. Biosensors can quickly and accurately respond to changes in plants and transmit data to researchers or farmers through wireless communication. Real-time monitoring of the nutritional status and health status of plants can help to gain insight into the adaptability and stress resistance of plants to the environment and provide support for the cultivation of original varieties with greater adaptability. Farmers can accurately fertilize, water, and prevent pests and diseases based on sensor data, improve crop yield and quality, and reduce waste of resources. In general, plant biosensor research is of great significance in the fields of environmental monitoring, biological research, agricultural application, environmental protection, and sensing technology, which can help solve practical problems and promote the development and application of science and technology.
Current status and perspectives of gene therapy in the treatment of haematological cancers
Authors: Sun Yuhan
Published: December 2023

Gene therapy holds great promise in the treatment of haematological cancers. Haematological cancers account for a significant portion of cancer cases worldwide, making gene therapy research in this area crucial. The emergence of breakthrough technologies, especially CRISPR-based gene editing, has enriched gene therapy possibilities and ushered in new opportunities for cancer treatment. Despite the potential benefits, gene therapy faces challenges related to safety and technical advancements. This work discusses practical applications of gene therapy, such as the use of monoclonal antibodies and gene transfer in haematological tumour cells. It also highlights the prospects of CRISPR gene editing technology, which has gained momentum in clinical applications for cancer treatment. However, it acknowledges potential risks and limitations, such as off-target effects and unpredictable translational outcomes. The conclusion emphasizes the need for further research to enhance long-term effectiveness, safety, and accessibility of gene therapy, using human genome sequencing, improved delivery technology, and better understanding of disease genes and biological mechanisms.
Fluorescence mechanism and biomedical applications of graphene quantum dots
Authors: Wang Ziqi
Published: December 2023

Graphene quantum dots (GQDs) are fluorescent graphene nanoparticle that have tunable emission wavelength, high emission intensity and biocompatibility. The fluorescence mechanism is still indecisive, yet explanations exist. Surface or edge defects and quantum confinement are two major explanations and they accounted for the florescence properties observed so far. GQDs quantum confinement is applied to change the emission wavelength. Surface functional groups usually improve biocompatibility and solubility. Under several cases, surface defects are also engineered to tune emission wavelength and intensity to serve specific engineering propose. GQDs have found applications in bioimaging, biosensing, and therapy. GQDs can generate high intensity emission in the NIR-II window which is ideal in in vivo bioimaging. GQDs can be generated from folic acid in a one-step procedure. The GQDs generated this way can track folate receptor and help cancer diagnostics. High intensity emission also enables GQDs to be used in photothermal or photodynamic therapy. Future applications will be promoted by a better understanding of GQDs fluorescence mechanisms.
Biomedical applications of fluorescent biosensors
Authors: Zhou Yifan
Published: December 2023

This study aims to systematically summarize the development history of fluorescent biosensors and their applications in biomedicine, and propose optimization strategies to promote the development of fluorescent biosensor technology according to the current challenges. This paper collects the literature of relevant research at home and abroad, and organizes and analyzes the basic principles, development history and biomedical applications of fluorescent biosensors. In addition, in view of the problems existing in fluorescent biosensors, some potential optimization strategies are proposed. After sorting out and analyzing the development history of fluorescent biosensors, it can be seen that the technology of fluorescent biosensors has made significant progress. In the field of biomedicine, fluorescent biosensors have been successfully applied to biomolecular detection, disease diagnosis and drug screening, showing great application potential. However, current fluorescent biosensors still face some challenges, such as light stability and sensitivity, which need to be further optimized. In summary, the application of fluorescent biosensors in biomedicine has broad prospects, but some technical challenges still need to be overcome.
Phenylketonuria (PKU): Causes, classifications, clinical symptoms, diagnosis and treatment
Authors: Zhang Lingtao
Published: December 2023

The autosomal recessive condition phenylketonuria (PKU) is brought on by mutations in the gene that codes for phenylalanine hydroxylase (PAH). Phenylalanine (Phe) builds up in the blood as a result of PAH mutations. Untreated PKU can result in several dangers, including brain damage. Due to factors including enhanced genetic testing and newborn screening, the number of PKU patients is predicted to rise. Therefore, it is necessary to popularize the knowledge of PKU in the society. Additionally, minimizing the occurrence of PKU symptoms is greatly aided by early identification and treatment of PKU. In this context, this review highly summarizes all aspects of knowledge about KPU, focusing on the genetic cause, classification, clinic symptoms, diagnosis, and treatment. Newborn screening and related diagnostic technologies, including the Guthrie test, the McCaman and Robins fluorescence assay, and Tandem mass spectrometry, are introduced in this paper. The dietary measures, PKU Formula, and two effective medications, Kuvan and Palynzio, are involved as well. In addition, state-of-the-art genetic techniques for diagnosis and treatment are also included. With an earlier and more accurate diagnosis, governments around the world should strengthen awareness of PKU and lead to the development of effective diagnostics and therapeutics. Finally, the purpose of this paper is to let more people know about PKU, strive for early detection and treatment, and do everything possible to avoid the occurrence of phenylketonuria symptoms.
Investigating the role of Elba3 in drosophila embryonic development
Authors: Wang Ruo-Tong
Published: December 2023

Elba (erythroid-myeloid lymphatic binding protein associated) is a transcription factor in fruit flies that plays a crucial role in regulating gene expression, particularly during embryonic development. Elba3, which acts as a transcription factor protein, exhibits significant involvement in the control of gene expression throughout embryogenesis and has been demonstrated to be essential for proper embryo development and central nervous system formation. In this work, by using CRISPR-Cas9 technologys results, I have been able to study the effects of manipulating the Elba3 gene in Drosophila embryos, providing insights into the function of Elba3 in the regulation of gene expression during embryonic development and Elba3 and Zelda are related to each other in a few different ways.
Metabolism system during exercise and its guiding value for exercise
Authors: Liu Yinghang
Published: December 2023

With the development of today's society, people's daily activities are becoming increasingly diverse, and sports are gradually integrated into people's daily lives. However, there are still biases and misunderstandings in social cognition regarding physiological knowledge of sports. Therefore, this paper aims to study the energy metabolism response during exercise, focusing on the metabolic mode of cellular respiration and providing guidance on exercise from this study. With the deepening of research, it can be understood the relationship between ATP and energy, recognized that the body generates ATP through three metabolism ways: glycolysis, ATP-PCR, and cellular respiration, and understood the differences between these three metabolism ways, also recognizing that they are crucial for the development of athlete performance. Finally, this paper will provide a method for athletes to train their metabolism system that combines long-term steady-state training with interval training.
Brain-targeted delivery of CRISPR/Cas9 mediated glioblastoma therapeutics
Authors: Liu Sixie
Published: December 2023

Glioblastoma multiforme (GBM) is a life-threatening malignant tumor of the central nervous system, for which there is currently no effective treatment. Its low survival rate has been interpreted as a result of its high proliferation rate, resistance to apoptosis, and the ability to create a microenvironment conducive to tumor growth. Recently, a powerful and accurate gene-editing tool, Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated Protein 9 (CRISPR/Cas9), has high potential in various scientific fields. Such technologies can manipulate cellular mechanisms and defective genes that lead to the progression of many serious diseases such as cancer. One of the major barriers to the application of this technique is the development of a delivery method to diffuse CRISPR/Cas9 efficiently and accurately to the target location in brain. Most existing delivery methods are failed to be translated into clinical result due to the lack of promising safety and efficiency. Thus, I will introduce several strategies here that can be used potentially for CRISPR-Cas9 system delivery in GBM treatment including the principle, advantages, limitations, and latest developments of these systems. This review is composed to provide a concise summary for future researchers to understand the current challenges and approaches in CRISPR/Cas9 mediated GBM therapeutics delivery.
Identifying the relationship between depression and cognitive neuroscience
Authors: Li Xilong
Published: December 2023

Major depression (MD) is increasingly prevalent worldwide and more practical treatments are in demand. Discovering its mechanisms and affective factors could help in finding better treatment and understanding how each individuals differences affect the mechanisms. This article focuses on discovering the relationship between depression and neuroscience, particularly on the cognitive aspect, emotion regulation, and brain structure. Three main executive functions in cognitive function, including updating, shifting, and inhibition are analyzed. Moreover, this paper indicates the relationship between dorsal anterior cingulate cortex (ACC) and posterior cingulate cortex (PCC) in the brain structure and depression by using functional magnetic resonance imaging (fMRI). With integrated information providing insights, several notable factors and mechanisms have been found. This proves that cognitive executive processes have a direct impact on emotion, where updating working memory can reduce the effects of negative emotions; however, shifting impairment tends to experience emotional dysregulation, and inhibitory deficits may impair adaptive emotion regulation processes. In addition, the prefrontal cortex (PFC) region of the brain structure manages the functions of emotion regulation and cognitive regulation. In a parallel understanding, cognitive dysfunction is associated with dynamic emotional states and MD psychopathology. Based on these findings, several possible treatments are subsequently put forward. Meanwhile, researchers discovered new directions to examine the relations between MD and neuroscience.
GMCVD: Detecting key modulating gut microbiota that contribute the cardiovascular disease risk toward personalized prevention
Authors: Li Daiying
Published: December 2023

Nowadays, cardiovascular disease (CVD) is one of the leading causes of death and disabilities worldwide. Atherosclerotic cardiovascular disease (ASCVD) is one of the most life-threatening subtypes of CVD. Recently, an increasing number of studies start to focus on the correlation and prediction of CVD based on the information of gut microbiome. In this study, by applying explanatory machine learning model, random forest-based computational pipeline called Gut Microbiome for CardioVascular Disease (GMCVD) was developed to conduct the ASCVD prediction and feature ranking. The top key several modulating gut microbiotas from genus and species levels Ire identified based on their strong contribution and correlation to the risk of CVD. These key disrupted microbiotas Ire validated by several external experimental studies, which demonstrate the reliability and efficiency of the machine learning based CVD risk prediction pipeline. With the detection of those specific modulating gut microbiotas, the personalized prevention method to reduce ASCVD risk using probiotics is provided based on varied microbiotas including Bifidobacterium, Clostridium, and Bacteroides. Therefore, GMCVD will facilitate the personalized prevention via gut microbiota to reduce the risk of cardiovascular disease.
The use and health effects of sugar substitute
Authors: Yin Yue
Published: December 2023

Due to the rising prevalence of obesity and the growing emphasis on health consciousness, an increasing number of individuals are opting to manage their weight by reducing their caloric intake through the regulation of sugar consumption. Sugar substitutes are commonly selected as primary alternatives to sugar due to their low caloric content and high level of sweetness. Recent research indicates that sugar substitutes may not be entirely effective in reducing overall calorie consumption. The impact on human metabolism is significant. This paper presents a comprehensive overview of the classification of sugar substitutes, examines the utilization of sweeteners in low-sugar food products available in the market, evaluates recent research findings regarding the safety of sugar substitutes and their effects on metabolism, and proposes potential considerations for individuals when selecting sugar substitutes as well as the future trajectory of the sugar substitute market.
Association between serum uric acid and blood glucose in diabetic individuals: NHANES 2017- Mar.2020
Authors: Yu Sijia
Published: December 2023

Studies have shown conceivable relationship among serum uric corrosive (SUA), blood glucose (BG) and diabetes mellitus (DM), yet there are not many which examine the association among SUA and BG. The goal of this study is to help or reject the past presumption of the examinations and further close the conceivable association of SUA, BG and DM. Concentrate on information is from Public Wellbeing and Nourishment Assessment Study (NHANES) 2017-2020 review data set. Correlations of various conceivable related qualities of a sum of 1221 members are incorporated by making sense of trademark table, univariate and multivariate straight relapse examination among SUA and BG. Information closes a potential negative relationship among's SUA and BG in the wake of representing all conceivable frustrating elements. In the univariate and multivariate models, it is shown that uric corrosive, Aspartate aminotransferase (AST), egg whites has negative relationship with expanding level of blood glucose, all out cholesterol, fatty substances, Alanine aminotransferase (ALT) has positive connection with expanding level of blood glucose. The affiliation stays huge in the awareness examination (P stays under 0.05). All in all, Serum uric corrosive may be adversely related with blood glucose in diabetic people.
Next generation armored CAR-T cells with a drug inducible cytokine circuit
Authors: Drew David , Li Xinyan , Su Michael , Wang Qingmei
Published: December 2023

Immunotherapies which direct the bodys own immune system against tumors are a safer and more efficacious alternative to other types of cancer treatments. Chimeric Antigen Receptor or CAR T cell therapy has emerged at the forefront of contemporary cancer immunotherapy research and is highly specific for a wide range of cancer types, resulting in improved patient outcomes. Early generations of CAR T cells were ineffective and failed to proliferate due to lack of costimulatory signals and immunosuppression within the tumor microenvironment (TME), but later generations of armored CAR T cells added costimulatory receptor domains and constitutive expression of stimulatory immunocytokines to ameliorate this. However, increased aggressiveness in T cells comes with issues such as off-site toxicity, fails to address relapse due to immune evasion, and combined with the prohibitive cost of engineering CAR T cells limit the efficacy of the treatment. Next generation CAR T-cells address these problems with the engineering of synthetic biological circuits that provide selective control over immune function in response to inducers. In this research proposal, we design a next generation armored CAR T cell with a small molecule inducible cytokine circuit, combining different synthetic biology approaches from previous research on CAR T cells to enhance the safety of the therapy by providing a reversible, safe, and rapid method of modulating CAR T cell stimulation.
Scream for me, Africa
Authors: Hoad Catherine
Published: December 2023

Review
Re-enacting the Trauma: Ritualising Turbo-Folk
Authors: Dražić Lena
Published: December 2023

Turbo-folk, a popular music genre originating in 1990s’ Serbia, still enjoys an immense popularity among Viennese residents with origins in the former Yugoslavia. The pilot study outlined here attempted to determine why a 25-year-old repertoire of songs is of such central importance to many listeners in the Austrian capital. As the research showed, informants view the interaction with turbo-folk as an experience outside their everyday lives requiring a particular time and space in order to unfold. To channel and express the strong emotions elicited by turbo-folk, actors employ a variety of strategies, one of which is singing along to the music. This practice is interpreted here as a ritual aiming to process the collective trauma constituted by a double loss of home. This ritual results in the construction of a collective “Yugo” identity that at the same time enables and ensues the process in a circular manner.
`Look here, you bunch of basement noise': Bob Dylan plays underground
http://dx.doi.org/10.5429/2079-3871(2010)v1i1.2en
Authors: Bratus Alessandro
Published: December 2023

Bob Dylan's Basement Tapes lay in a critical phase of the singer's career, in the shift from a production strictly based on folk-revival models to a new way of songwriting, based on his new electric sound presented in the live and recordings of 1965. In this article a brief analytical survey on four song from that period gives some overall indication about how to look at this repertoire and about its place in the context of the singer’s career, as well as in the history of American popular song.
Who Sells Out?: Petra Haden in the Age of Mechanical Reproduction
 doi:10.5429/2079-3871(2010)v1i2.7en
Authors: Letts Marianne Tatom
Published: December 2023

In 2005, Petra Haden released her version of The Who Sell Out, notable for the meticulousness and creativity with which she mimicked the instruments on the album with only an eight-track recorder and her voice. This paper examines the ways in which Haden’s interpretation of the classic album elevates it into the realm of “high art” while retaining its status as a commodity within the realm of popular music. Haden’s live reinterpretation (with her band the Sellouts) calls into question what constitutes the “authentic” version of the album, since the current lineup of the Who no longer performs the material.
Del discurso a la performance: la producción de significaciones de nacionalidad en el “jazz argentino”
http://dx.doi.org/10.5429/2079-3871(2011)v2i1-2.7es
Authors: Corti Berenice Maria
Published: December 2023

Within the framework of Argentine jazz studies we focus here on senses of nationalism built in to speeches of and about this music, proposing to focus on those produced in the context of performance as a productive space of social meanings. At first, we contrast these meanings with hegemonic discourses of nationality in Argentine music, and analyze how both senses present tensions related to the signification processes within and about music. The article also includes a brief critical review of the theoretical discussions on meaning construction around identity and nationality, understanding the need to place the discourse studies as a part of the musical complex sound/performance.

RESUMEN
A partir de trabajos de investigación realizados en torno al jazz argentino, nos enfocamos aquí en los sentidos de nacionalidad construidos en los discursos de y sobre de esta música, proponiendo además un enfoque para aquellos producidos en el marco de la performance como espacio de creación de significaciones sociales. Contrastamos esos sentidos con los discursos hegemónicos sobre músicas nacionales en el país, y analizamos de qué forma unos y otros entran en tensión en el marco de la producción de significaciones en y sobre la música. La propuesta incluye también una breve revisión crítica de las discusiones teóricas sobre construcción de sentidos en identidad y nacionalidad, colocándose la necesidad de ubicar los estudios discursivos también el marco del complejo musical sonido/performance.
How did popular music come to mean música popular?
http://dx.doi.org/10.5429/2079-3871(2011)v2i1-2.3en
Authors: Jordán González Laura F. , Smith Douglas Kristopher
Published: December 2023

The field of popular music studies has grown to include participation from many different parts of the world, comprised of cultural-linguistic spaces that view popular music in a dissimilar and sometimes contradictory light. That said, there have been situations where two or more very different definitions of popular music exist side by side, further complicating the coherence of the field. Focusing on Spanish-speaking Latin America, we set out to examine what popular music and música popular have meant in some of their respective sociolinguistic spaces, and argue that disparities of legitimacy between institutions that are engaged in the study have contributed to a terminological confusion that must be further engaged with if it is to be overcome.
The Introduction of Popular Music Studies to Ghanaian Universities
http://dx.doi.org/10.5429/2079-3871(2011)v2i1-2.4en
Authors: Collins John
Published: December 2023

Although the teaching if of African traditional and art music in Ghanaian universities began from independence in 1957, the introduction of local popular music has taken much longer, partly a consequence of imported high-art notion that treated popular music as trivial, ephemeral and low-brow. Although Nkrumah utilised local popular, traditional and arts music in nation building after his overthrow in 1966 his vision was never fully transmitted into the universities where students were only expected to be bi-musical, i.e. familiar with traditional music and art music. The first evidence of a growing Ghanaian academic interest in popular performance studies was the pioneering work of the university lecturers Efua Sutherland, K.N. Bame and Attana Mensah during the 1960s/70s. But this area was not included in the university curriculum until the 1990s, when the University of Ghana changed its position due to several factors. One was the burgeoning local popular music industry (after the music industry decline during the 70s/80s military regimes) and the consequent job opportunities for students. Another was the rise of pop influenced local gospel music from the 1980s that sanctified the guitar and dance-band music. Thirdly there was an interest in Afropop by foreign world music students coming in large numbers after Ghana’s economic liberalisation of the late 1980’s.
Rock Clubs and Gentrification in New York City: The Case of the Bowery Presents
Authors: Holt Fabian
Published: December 2023

This article offers a new analytical perspective on the relation between rock clubs and gentrification to illuminate broader changes in urbanism and cultural production in New York City. Although gentrification is central to understanding how the urban condition has changed since the 1960s, the long-term implications for popular music and its evolution within new urban populations and cultural industries have received relatively little scholarly attention. Gentrification has often been dismissed as an outside threat to music scenes. This article, in contrast, argues that gentrification needs to be understood as a broader social, economic, and cultural process in which popular music cultures have changed. The argument is developed through a case study of the Bowery Presents, a now dominant concert promoter and venue operator with offices on the Lower East Side. Based on fieldwork conducted over a three-year period and on urban sociological macro-level analysis, this article develops an analytical narrative to account for the evolution of the contemporary concert culture in the mid-size venues of the Bowery Presents on the Lower East Side and Williamsburg, Brooklyn, as a particular instance of more general dynamics of culture and commerce in contemporary cities. The narrative opens up new perspectives for theorizing live music and popular culture within processes of urban social change. The article begins by reviewing conventional approaches to rock music clubs in popular music studies and urban sociology. These approaches are further clarified through the mapping of a deep structure in how music scenes have framed the relationship between clubs and gentrification discursively. The article then examines the evolution of the Bowery Presents within the expansive process of gentrification. The focus is placed here on the cultural profile of the now dominant mid-size venue culture and on three stages in the development of the company and its field-structuring impact on rock clubs on the Lower East Side in particular. The conclusion sums up the key points and suggests that gentrification might involve changing conditions of artistic creativity and performance, with implications for fundamental aspects of urban life; a point illustrated by the trajectory of Occupy Wall Street.
Beyond and Before: Progressive Rock since the 1960s
Authors: Kaler Michael John
Published: December 2023

Beyond and Before:

Progressive Rock since the 1960s

Paul Hegarty and Martin Halliwell

New York: Continuum Books, 2011
Subcultural Theory: Traditions and Concepts
Authors: Driver Christopher
Published: December 2023

Subcultural Theory:

Traditions and Concepts

J. Patrick Williams

Malden, MA: Polity Press, 2011
Flamenco Music and National Identity in Spain
Authors: Hytönen-Ng Elina T.
Published: December 2023

Flamenco Music and National Identity in Spain

William Washabaugh

Farnham: Ashgate Popular and Folk Music Series, 2012
Languages of Global Hip Hop
Authors: Baker Catherine
Published: December 2023

Languages of Global Hip Hop

Marina Terkourafi (Ed.)

London: Continuum, 2010

ISBN 9781441140265 (PB)
Cultural Globalization and Music: African Artists in Transnational Networks
Authors: Muehrer Rachel
Published: December 2023

Cultural Globalization and Music:

African Artists in Transnational Networks

Nadia Kiwan and Ulrike Hanna Meinhof

Basingstoke: Palgrave Macmillan, 2011
Vinyl: A History of the Analogue Record
Authors: Whelan Andrew
Published: December 2023

Vinyl: A History of the Analogue Record

Richard Osborne

Farnham, UK: Ashgate Popular and Folk Music Series, 2012

ISBN: 978-1-4094-4027-7 (HB)

RRP: £55.00 (HB)
Musical Performance and the Changing City: Post-Industrial Contexts in Europe and the United States
Authors: Rogers Ian Keith
Published: December 2023

Musical Performance and the Changing City: Post-Industrial Contexts in Europe and the United States

Holt, Fabian,Wergin, Carsten

New York ; London : Routledge, 2013

9780415644860 (hardback : alk. paper)
Song Means: Analysing and Interpreting Recorded Popular Song
Authors: Avdeeff Melissa
Published: December 2023

Song Means: Analysing and Interpreting Recorded Popular Song

Allan F. Moore

Farnham and Burlington VT: Ashgate, 2012
Music, Politics, and Violence
Authors: Carroll Mark Stephen
Published: December 2023

Music, Politics, and Violence

Edited by Susan Fast and Kip Pegley.

Middletown CT: Wesleyan University Press, 2012.
Art to Commerce: The Trajectory of Popular Music Criticism
Authors: Conner Thomas , Jones Steve
Published: December 2023

This article reports the results of a content and textual analysis of popular music criticism from the 1960s to the 2000s to discern the extent to which criticism has shifted focus from matters of music to matters of business. In part, we believe such a shift to be due likely to increased awareness among journalists and fans of the industrial nature of popular music production, distribution and consumption, and to the disruption of the music industry that began in the late 1990s with the widespread use of the Internet for file sharing. Searching and sorting the Rock’s Backpages database of over 22,000 pieces of music journalism for keywords associated with the business, economics and commercial aspects of popular music, we found several periods during which popular music criticism’s focus on business-related concerns seemed to have increased. The article discusses possible reasons for the increases as well as methods for analyzing a large corpus of popular music criticism texts.
“Surely people who go clubbing don’t read”: Dispatches from the Dancefloor and Clubland in Print
Authors: Morrison Simon
Published: December 2023

In the context of the UK dance club scene during the 1990s, this article redresses a presumption that “people who go clubbing don’t read”. It will thereby test a proposed lacuna in original journalist voices in related print media. The examination is based on key UK publications that focus on the musical tropes and modes of the dancefloor, and on responses from a selection of authors and editors involved in British club culture during this era The style of this article is itself a methodology that deploys ‘gonzo’ strategies typical of earlier New Journalism, in reaching for a new approach to academicism. In seeking to discover whether the idea that clubbers do not read is due to inauthentic media re/presentations of their experience on the dancefloor, or with specific subcultural discourses, the article concludes that the authenticity of club cultural re/presentation may well be found in fictional responses.
Death Metal and Music Criticism: Analysis at the Limits
Authors: Ferrarese Marco
Published: December 2023

Book Review

Michelle Phillipov, Death Metal and Music Criticism: Analysis at the Limits, Lexington Books, 2012.
Editorial Introduction: Popular Music in Education, Special Issue
Authors: Green Lucy , Lebler Don , Till Rupert
Published: December 2023

This Popular Music in Education (PME) special issue includes contributions discussing developments in several countries, including Argentina, Australia, Brazil, Canada, Germany, Singapore and the United States. It covers a range of approaches, exploring technology, hermeneutics, theory, guitars, jazz, songwriting, DIY/DIWO, politics and music industry perspectives. As music institutions have increasingly opened their doors to popular music, this has inevitably led to a greater level of interest in how you teach and learn popular music. PME is presenting a louder presence within Popular Music Studies (PMS), as the ground prepared by PMS has made space for a wave of new PME courses and students to sweep through educational contexts. In the wake of such expansion, this special issue intends to promote a further understanding of pedagogical best practice. The development of PME is something that is long overdue, and that seems likely to greatly expand and enrich the frame of PMS.
Overview of Nephrotic Syndrome in Arab Children: Systematic review
Authors: Amir Fayyaz Shaikh Sardar Muhammad  , Jamal H Alanezi Fawaz , Ibrahim Muqbil W Alanazi  , Shabikan M Alanazi Badar , Khalil A Alanazi Abdullah , Hadi alenezi Yuosef , Saleh mobark Almarjan Khalid , Zaedan M Alenezi Eissa , Awadh R Alanazi Ibrahim , Malek Ramadan Alenezi  , Subhi hindi alanazi Abdulrhman , Yahya Ahmed Alzahrani Ziyad , Alsayed Alanazi Naif
Published: December 2023

Background: Nephrotic syndrome (NS) is documented as a common chronic disease in childhood. Children with this illness repeatedly show periorbital swelling with or without generalized edema. It was estimated that the annual incidence rate of NS in children aged below 16 years is 2 to 7 new cases per 100 000, with a prevalence rate of 16 cases per 100 000.
Objectives: This systematic review comprehensively investigates the recently published literature on incidence and pattern of nephrotic syndrome in infants and children.
Methods: PubMed, SCOPUS, Web of Science, Science Direct, and Google Scholar were systematically searched for relevant literature. Rayyan QRCI was employed throughout this comprehensive process.
Results & interpretation: This review included nine studies with a total of 1418 patients. The incidence, mean age, sex dominance in different sample groups and the histopathological patterns were differ according to many factors.
Sistem Tata Kelola Kearsipan di Kantor Kepala Desa
Authors: Nurul Laili Herzegovina Rani , Mokhamad Saiful Hasan
Published: December 2023

Klanting Village is one of the villages in Indonesia's East Java province's Sukodono sub-district, Lumajang Regency. Villages in the Lumajang Regency are included within the borders of Klanting Village. Farm laborers, domestic helpers, breeders, civil servants, and other laborers are the most in-demand jobs in Klanting Village. The Klanting Village Office served as a model for this article because of its nearly identical issues with archival administration. The goal of this study was to identify the challenges the village government encountered in running the village archives. A qualitative research approach was adopted, and it is descriptively reported. The two stages of observation and interview with village employees who manage archives were used to get the data. Additionally, information was gathered through document and literature studies, specifically through books on archives, laws governing archives, and regulations governing archives. The stages of data reduction, data presentation, and conclusion or verification make up the data analysis procedure used in this study. The study's findings indicate that, despite the fact that it is not ideal, village archives are generally managed well. This is due to a number of factors, including a dearth of village employees with the necessary skills and knowledge to handle archives, a lack of facilities and infrastructure, and a lack of funding for archive management. The purpose of this research is to inform the village about effective archival management, which will help village governance and enhance community services.
Pengarsipan Berbasis Dokumentasi Media Sosial “Gendis Sewu” dalam Perspektif Maqasid Syariah
Authors: Rachman Rio Febriannur , Ghulam Zainil
Published: December 2023

This article discusses one of the public policies implemented by the Surabaya Library and Archives Service. This policy takes the form of documentation-based archiving on social media which is carried out in the Gendis Sewu program. The social media platforms used are websites, YouTube, and an application called "Taman Kalimas". Gendis Sewu is the Storytelling and Writing Movement Sewu, a training that is held every week in “Taman Bacaan Masyarakat” (Community Reading Parks) spread across 31 sub-districts throughout Surabaya. This storytelling and writing training has a target of "sewu", sewu in Javanese means a thousand. The program's target is thousands of children and teenagers whose literacy skills continue to be developed. The theories used are public policy, technological determination, maqasid Sharia, also reinforced by the concept of Sustainable Development Goals. The method used is qualitative with a literature study approach. This study explains how the implementation of this policy in society is seen from an Islamic perspective. The results of this research: 1) Archiving policies based on social media documentation are in accordance with principle stages such as planning, implementation and evaluation; 2) This kind of digital archiving is in harmony with a number of Sustainable Development Goals points where it occurs more effectively, efficiently and environmentally friendly; 3) This innovation has the spirit of Islamic teachings, seen from the concept of maqasid sharia al-ammah, which has an excellent service orientation for citizens.