bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Athletic Training Through the Integration of Convolutional Neural Networks and Feature Extraction Techniques
Authors: Li Kun , Aghdam Mohammad Reza Ghavidel , Khishe Mohammad , Naghavi Alireza
Published: November 2024

This paper presents an innovative approach to improving athlete performance using advanced technology. It introduces a convolutional neural network (CNN) designed to classify training videos of athletes. The CNN architecture includes layers for processing data, such as convolutional, pooling, fully connected, and activation function layers. These layers help identify different types of training, like sprinting, strength exercises, and agility drills. Critical features like motion patterns, body posture, speed, and repetition rate are analyzed to boost performance. The model uses a structured data preprocessing and fusion strategy to enhance accuracy. Tested on the UCF101 dataset, the model demonstrated excellent accuracy, precision, recall, and F1-score results through holdout and K-fold validation methods. A comparison with traditional classifiers shows the proposed method’s superior performance. This research offers significant advancements in personalized sports training and real-world action recognition.
Risk Evaluation of Dike Engineering Based on Game Theoretic Combinatorial Empowerment Two-Dimensional Cloud Modeling
Authors: Yao Zihan , Ren Jie , Zhang Lei
Published: November 2024

Dike project is an important part of the flood control engineering system, so the research of risk evaluation method of dike project is of great significance for the protection of people's property and life safety, urban economy and sustainable development of the environment. Therefore, this paper establishes a two-dimensional cloud model for risk assessment of dike projects based on game-theoretic combinatorial empowerment. First of all, according to the statistical results of the data proposed from the flood inundation and destruction damage, infiltration damage, deformation and destabilization damage of the three dike failure modes for risk evaluation index analysis, through the representative and scientific risk evaluation factors, to build a comprehensive risk evaluation index system; Secondly, for the impact of too much subjectivity of data and too much interrelationship between indicators, the idea of combinatorial assignment based on game theory is adopted, and the calculation of indicator weights is carried out through the G1-C-OWA subjective assignment method and the CRITIC objective assignment method, which weakened the impact on the accuracy of the evaluation results to a certain extent; Then, according to the fuzzy and uncertainty characteristics of the risk index data of dike project, a two-dimensional cloud model is introduced, and the corresponding cloud digital features are calculated from the two aspects of risk probability and risk consequences, so as to improve the accuracy of the risk evaluation results and compare them with the standard risk cloud, and to determine the risk level of the dike project in a clear and intuitive way. Finally, the method is applied to the actual project of remote dike of Han River in the middle and lower reaches of Yangtze River for risk evaluation, and the evaluation results obtained are basically in line with the actual risk situation faced by the project, which verifies the reasonableness of the method and the value of its practical application.
A Secure data-driven algorithm against malicious intrusion signals in mobile communication networks
Authors: Yu Yongfei , Baza Mohamed , Rasheed Amar
Published: November 2024

Intrusion signals in mobile communication networks are often disguised as normal communication signals to attack, which is highly covert. This makes it difficult to be accurately recognized and increases the danger of data leakage. For this reason, this paper proposes a full link security defense algorithm against malicious intrusion signals in mobile communication networks based on data-driven technique. This algorithm uses the support vector machine technology to construct an identification model against the malicious intrusion signal of the full link and introduces the firefly algorithm to optimize the support vector parameters of the model to ensure the accuracy of the model in identifying the malicious intrusion signal. In addition, this algorithm uses a network full link security defense model based on dynamic camouflage technology to dynamically simulate any element of the full link in the mobile communication network, and at the same time constructs heterogeneous executives to distribute the results of the malicious intrusion signal to each selected heterogeneous executor. Experimental results show that the proposed algorithm can accurately identify different types of malicious intrusion type signal samples, so that the interception rate of the intrusion defense system against malicious intrusion signals is greater than 99%, and the important data loss rate is less than 1%.
Diversified Subsistence Strategies in Early Sedentary Populations of Mainland Southeast Asia: Insights from the Faunal Remains at Lò Gạch, southern Vietnam
Authors: Trần Thị Kim Quý , Hertler Christine , Đặng Ngọc Kính , Piper Philip J.
Published: November 2024

In the past two decades, zooarchaeology combined with improved dating techniques has provided significant insights into the initial appearance of domestic animals in Southeast Asia. The suite of domestic animals commonly associated with Neolithic introduction—pigs (Sus scrofa), dogs (Canis lupus familiaris), chicken (Gallus gallus), and cattle (Bos sp.)—arrived early in some areas but not others. In Southern Vietnam, analysis of animal bone assemblages and radiocarbon dating of Neolithic sites (c. 4200–3500 cal. BP) indicate that early managed animal populations were linked to sedentary lifestyles. Research has shown that pigs and dogs are present in the Neolithic, but cattle and chicken are absent. But the timing of integration of these domesticates into economic strategies remains unclear due to the lack of zooarchaeological studies on early metallurgical sites. Lò Gạch, the focus of this project, an early copper-base metallurgy settlement on the Vàm Cỏ Tây River, shows that animal management was supplemented by hunting around 3000–2200 cal. BP, with limited evidence of cattle and no domestic chicken. This highlights the complexity and regional variability in the spread and integration of domestic animals in the region.
Beyond the Click: Exploring the Dynamics of E-Learning in Advanced English Language Learning – a case study
Authors: Mekheimer Mohamed
Published: November 2024

This qualitative case study, guided by Social Cognitive Theory, investigated the interplay of technological self-efficacy, intrinsic motivation, and e-learning strategies among three advanced university students enrolled in an online English language program in the Middle East. The study found that technological self-efficacy, particularly related to digital literacy and confidence in using online tools, significantly influenced students' e-learning strategy choices. Intrinsic motivation, driven by a desire for personal growth and future opportunities, was a key driver of proactive engagement and strategy implementation. The study also highlighted the importance of contextual factors, including curriculum design, assessment practices, virtual classroom instruction, and opportunities for peer interaction, in shaping successful e-learning experiences. Findings emphasized the need for educators in this region to prioritize the development of technological self-efficacy, foster intrinsic motivation, and design learning environments that encourage diverse e-learning strategies, promote learner agency, and create a supportive learning community. Future research should explore these factors within larger student populations to identify patterns and developmental trajectories in diverse e-learning contexts.
Developing a cultural sustainability assessment framework for environmental facilities in urban communities
Authors: Zhang Linghao , Zhao Qixun , Hou Jie
Published: November 2024

Cultural sustainability is essential for sustainable urban development, yet its integration into environmental facility design in urban community is often overlooked. This paper proposed a 4-level hierarchical framework with 30 indicators to assess the cultural sustainability of urban environmental facilities. The framework was organized into three dimensions: cultural core, cultural representation, and cultural impetus, focusing on preserving cultural heritage, fostering emotional and identity connections through design, and strengthening community resilience. Using qualitative and quantitative methods, including Delphi and Bayesian Best-Worst Methods (BWM), the indicators were refined and weighted. Case studies in Shanghai and Guangzhou demonstrated the framework’s practical application in assessing cultural sustainability and guiding urban design and policy decisions. This study provided urban planners and designers with an adaptable tool to incorporate cultural sustainability into rapidly changing urban environments, offering insights for promoting resilient and cohesive communities.
Correlation of multiple peripheral blood parameters with metastasis and invasion of papillary thyroid cancer: a retrospective cohort study
Authors: Chen Xiao , Wang Han-yu , Yu Lu , Liu Jia-qi , Sun Hui
Published: November 2024

Objective
The primary progression mechanisms of papillary thyroid cancer (PTC) involve the development of lymph node metastasis and thyroid capsular invasion. This study aimed to identify high-risk populations for these conditions in PTC based on various peripheral blood tests, and to investigate the factors significantly associated with such populations.
Methods
A total of 4,557 patients with papillary thyroid cancer were retrospectively analyzed in this study. Principal Component Analysis (PCA) and cluster analysis were conducted using the results from 45 different peripheral blood tests. High-risk and low-risk clusters were defined by comparing the prevalence of metastasis and invasion across different clusters. Key indicators that significantly differed between clusters were identified to examine the correlation between peripheral blood parameters and tumor progression.
Results
Preoperative examination measures categorized patients into two distinct clusters. Patients in Cluster 0 exhibited a significantly higher rate of tumor metastasis and invasion compared to those in Cluster 1, and were thus categorized as the high-risk group. Following PCA, four principal components showing the most significant differences between the clusters were identified. These components were further analyzed to determine the most crucial peripheral blood parameters. Subsequent multiple logistic regression analysis revealed that parameters such as transaminase levels, white blood cell and red blood cell counts, coagulation time, and thyroid hormones were significantly associated with membership in Cluster 0.
Conclusion
Several peripheral blood parameters, including transaminase levels, white and red blood cell counts, coagulation time, and thyroid hormones, are linked to the metastasis and invasion of papillary thyroid cancer. These findings suggest that peripheral blood parameters hold potential predictive value for disease progression in PTC, offering a basis for more targeted and effective clinical management.
WITHDRAWN: Resveratrol alleviates testicular toxicity induced by anti-PD-1 through regulating the NRF2-SLC7A11-GPX4 pathway
Authors: Tuerxun Halahati , Zhao Yixin , Li Yawen , Liu Xingyu , Wen Shuhui , Zhao Yuguang
Published: November 2024

Background: Fertility preservation is a critical concern for reproductive-age cancer survivors, as conventional cytotoxic therapies can cause irreversible damage to the reproductive system, potentially depriving them of the ability to have children in the future. Immune checkpoint inhibitors (ICIs), including anti-programmed cell death protein 1 (anti-PD-1), have become a standard therapeutic approach for various malignancies. However, the impact of ICIs on reproductive function and fertility is not well understood and remains a largely unexplored domain.
Methods: Male C57BL6/J mice with B16 melanoma were assigned into four groups: control , anti-PD-1 (ICI) , RSV, anti-PD-1 with RSV (ICI/RSV) group. RSV and ICI/RSV groups received RSV (40 mg/kg) orally every other day for one month, while controls received the vehicle. ICI and ICI/RSV groups were injected with anti-PD-1 antibody (10 mg/kg) weekly, and controls received IgG2b kappa antibody. Parameters like body and testicular weight, sperm concentration, and Western blotting for ferroptosis markers were measured. Furthermore, oxidative stress biomarkers, lipid oxidation factors, and gonadal hormone levels were quantified using commercial kits.
Results: Anti-PD-1 therapy caused male reproductive dysfunction, as evidenced by reduced sperm concentration, altered gonadal hormone levels, and disruption of blood-testis barrier (BTB) integrity. Furthermore, ferroptosis was a key mechanism in anti-PD-1-induced testicular dysfunction, characterized by disrupted iron homeostasis, elevated lipid peroxidation, and suppression of the system Xc−/glutathione peroxidase 4 (GPX4) axis. Additionally, anti-PD-1 therapy diminished antioxidant defenses by inhibiting the nuclear factor erythroid 2-related factor 2 (NRF2) pathway, thereby increasing the susceptibility to ferroptosis. Crucially, RSV treatment ameliorated anti-PD-1-induced reproductive dysfunction. This was achieved by reducing T cell infiltration, lowering interferon-gamma levels, activating the NRF2 pathway, and maintainingiron and lipid homeostasis.
Conclusions: Our study demonstrates that anti-PD-1triggers oxidative stress and ferroptosis in the testis, causing male reproductive dysfunction. Resveratrol may offer protection against testicular toxicity associated with anti-PD-1, particularly through its antioxidant and anti-ferroptosis properties.
Patients with overlapping dermatomyositis and psoriasis: An experience from a tertiary center and review of the literature
Authors: Pomianoski Beatriz Westphalen , Shinjo Samuel Katsuyuki
Published: November 2024

Background
The coexistence of dermatomyositis (DM)/clinically amyopathic DM (CADM) and psoriasis is rare, and has been described in a few case reports. Therefore, this study aimed to analyze this entity from our tertiary center and review the relevant literature.
Methods
This retrospective observational cohort study included patients with DM/CADM and psoriasis between 1998 and 2024. A systematic literature review was also conducted.
Results
Nine of 331 patients with DM (n = 265)/CADM (n = 66) had psoriasis; six were female, and all were of white ethnicity. The median age at DM diagnosis was 38 years (range: 18–78), and at psoriasis diagnosis was 43 years (range: 18–81), with a median interval of four years between diagnoses. The follow-up showed that six patients were discharged, two died, and one continued follow-up. The main comorbidities included systemic arterial hypertension (n = 3) and diabetes mellitus (n = 3). Four patients presented with varicella zoster (n = 1) or pulmonary tuberculosis (n = 3). Regarding literature review, there were 15 articles that reported a total of 17 cases of overlapping DM/CADM and psoriasis. However, variability was observed in the DM/CADM diagnostic criteria. The average age at DM diagnosis in the literature was 32.3 years (range: 2–59), whereas psoriasis was an average of 31 (7–63) years. Female patients were predominant.
Conclusion
This investigation identified the rare coexistence of DMPs, revealing older age at diagnosis ages and a higher prevalence of CADM among DM patients. With a median age of 38 years for DM and 43 years for psoriasis, our findings align with those in the existing literature. However, variability in the diagnostic criteria highlights the need for standardized approaches to improve patient management.
Model Climato-touristic Comfort in the Southern Mediterranean Coast: Case of Algiers, Algeria
Authors: HAMEIDIA Nesrine. , MEDJERABE Abderrahmane.
Published: November 2024

Tourism is a vital socio-economic contributor in Mediterranean regions. Recent studies have focused extensively on the climatic potential for outdoor tourism activities. However, the issues identified in these studies are not incorporated into the Tourism Climate Index (TCI), which has been repeatedly criticized for its weighting methodology. To address these shortcomings, a Model of Climato-Touristic Comfort (MCTC) has been developed using the Analytic Hierarchy Process (AHP). This model assesses the climatic suitability of outdoor tourism destinations, underscoring its importance in maintaining the competitiveness of both coastal and urban destinations. Calculations were performed at tri-hourly intervals for the reference period from 2000 to 2021. The findings reveal that the climate in Algiers is generally comfortable for an average of more than 180 days per year, approximately sixty days are classified as moderate, and the remaining days are categorized as uncomfortable.
Analysis of GLCM-feature-based dimensionality reduction and feature extraction methods for classifying fabric design patterns by using video data
Authors: Mamun Abdullah Al , Uddin Mohammad Abrar , Kim Taeil , Bappy Mahathir Mohammad
Published: November 2024

Manufacturing industries now leverage high-dimensional streaming video data from diverse sensors, represented as tensors (multidimensional arrays of channels × signals × time), for real-time monitoring, inspection, and quality control; however, this data often contains redundancy and captures only a subset of the complete dataset. Selecting effective dimensionality reduction and feature extraction methods for high-dimensional data structures remains challenging. To address these challenges, this paper presents a comparative framework for effective dimensionality reduction and feature extraction, utilizing supervised methods—Principal Component Analysis (PCA) and Independent Component Analysis (ICA)—alongside the unsupervised Multilinear-PCA (MPCA), which can more effectively handle multidimensional tensor structures compared to the 1-D or 2-D limitations of PCA and ICA. We evaluate this comparative framework for classifying fabric design patterns using high-dimensional video data captured from various fabric surface weave patterns. The videos are converted into sequential RGB frames and analyzed using the Gray-Level Co-occurrence Matrix (GLCM) for feature extraction, after which the dimensionality of the GLCM features is reduced with PCA, ICA, and MPCA, and the features are classified using supervised machine learning techniques for fabric design pattern recognition. MPCA achieves a 0.022% dimensionality reduction by extracting uniformly distributed features that effectively capture correlated fabric design patterns, unlike the less organized distributions from PCA and ICA. The fabric pattern classification accuracy achieved with MPCA, PCA, and ICA was 99.02%, 95.21%, and 92.68%, respectively. These results suggest that the proposed framework effectively facilitates dimensionality reduction and feature extraction in both supervised and unsupervised methods for high-dimensional video data.
Improving baseline information on over-looked generalists: occurrence and mitochondrial DNA diversity of Campbell’s (Cercopithecus campbelli) and green monkeys (Chlorocebus sabaeus) in Guinea-Bissau, West Africa
Authors: Colmonero-Costeira Ivo , Djaló Mamadú Lamine , Fernandes Nelson , Borges Filipa , Aleixo-Pais Isa , Gerini Federica , Costa Mafalda , Minhós Tania , Silva Maria Joana Ferreira da
Published: November 2024

Campbell’s (Cercopithecus campbelli) and green monkeys (Chlorocebus sabaeus) are sympatric medium-sized West African guenons (tribe Cercopithecini) that are generally understudied in most of their distribution. Both species are ecological generalists and are globally considered non-threatened, but populations are decreasing locally. National conservation management lacks baseline information on local populations of primate species. C. campbelli and Chl. sabaeus are considered the most abundant primates out of the ten extant species and are the most frequently hunted for meat consumption. Here, we aimed to update the occurrence and estimate the country-wide mitochondrial (mtDNA) genetic diversity for both species. From 2008 to 2022, we conducted surveys in four mainland protected areas and on the islands of the Bijagós archipelago where primates are known to occur. We identified C. campbelli populations outside their known distribution. We found relatively high mtDNA diversity for both species in the mainland and lower or no diversity in insular populations. Our results show significant signals of geographically induced mtDNA differentiation, particularly in C. campbelli, which pattern of population structure suggests female philopatry. In constrast, we found divergent Chl. sabaeus haplotypes at geographically close locations, suggesting female dispersal. We identified differentiated haplogroups with an estimated divergence time of 1.53 in C. campbelli and 1.16 Ma in Chl. sabaeus, possibly linked to Pleistocene climatic fluctuations. Our results add further evidence that Guinea-Bissau harbors high genetic diversity for primate species and the country should be prioritized for conservation in West Africa.
Semantic Representation of Preclinical Data in Radiation Oncology.
Authors: Giraldo Olga , Sabyrrakhim Abumansur , Roscher Mareike , Euler-Lange Rosemarie , Baumann Michael , Kurth Ina , Hadiwikarta Wahyu Wijaya
Published: November 2024

Background: In radiation oncology, the data generated from preclinical trials serve as initial validation for treatment effectiveness and optimizing clinical approaches by unraveling molecular mechanisms underlying different treatment responses. Therefore, it is important to standardize the practice in managing preclinical trial data to ensure consistency and reproducibility across studies, promoting collaboration, and facilitating regulatory review. The primary goal of this work is to standardize the representation of data collected from preclinical radiobiology and radiation oncology studies as a way to facilitate knowledge discovery. To achieve this goal, we combined ontology with semantic Web techniques to publish mapped data and easily query them using SPARQL Protocol and RDF Query Language (SPARQL).
Results: We expanded the Radiation Oncology Ontology (ROO) to include terminology related to the exposure of animal models to treatment, animal model’s demographic characteristics; as well as clinical information in live animals. The extended ROO contains 123 new entities (89 classes, 29 data properties and 5 object properties). We combined the extended ontology with Semantic Web technologies to demonstrate how to integrate and query data from different relational databases.
Discussion: The use of ontologies and semantic web tools are a way to comply to the FAIR principles. FAIR preclinical data improve collaboration, transparency, and reproducibility in radiotherapy research.
EXPRESSION OF p16 AND Ki-67 IN ORAL SQUAMOUS CELL CARCINOMA
Authors:   Junior Resident, Department of Pathology, Muzaffarnagar Medical College, Muzaffarnagar, Uttar Pradesh., Kaur Baldeep , Kumar Rajnish ,   Professor, Department of Pathology, Muzaffarnagar Medical College, Muzaffarnagar, Uttar Pradesh., Varshney Anupam ,   Professor and Head of Department, Department of Pathology, Muzaffarnagar Medical College, Muzaffarnagar, Uttar Pradesh., Tyagi Meenakshi ,   Professor, Department of Pathology, Muzaffarnagar Medical College, Muzaffarnagar, Uttar Pradesh.
Published: November 2024

Introduction:Oral Squamous Cell Carcinomais a major health challenge with high recurrence and poor prognosis.Asper Globocan 2022, lip and oral cancer ranked 16th in terms of incidence with 389,485(2%)newcases. p16 helps identify HPV infection and induces apoptosis, while Ki-67, a key cell cycle regulator, is crucial for assessing cell proliferation, tumor development and prognosis. Aim: The study aims to evaluate the immunohistochemical expression of p16 and Ki-67 in oral squamous cell carcinoma and correlation with various clinicopathological parameters. Material and Methods: This descriptive analysis was conducted at Muzaffarnagar Medical College & Hospital, involving 50 histologically confirmed oral squamous cell carcinoma cases. The study involved p16 and Ki-67 expression through immunohistochemistry on histologically diagnosed OSCC cases and scoring was done. Results: The study found that most OSCC patients belong to fifth and sixth decades of life, with buccal mucosa being the most affected site. Tobacco use was prevalent among the patients. Most cases were moderately differentiated. p16 and Ki-67 expression werehigher in poorly differentiated cases. Positive p16 expression was observed in 38% of the cases but showed no significant correlation with age, gender, or histological grade. However, significant associations were found between age, histological grade, and Ki-67 expression. Conclusion: This study concluded that p16 expression was positive in 38% of OSCC cases, with higher rates in poorly differentiated tumors, but no significant links to age, gender, or histological grade. Ki-67 levels, higher in poorly differentiated cases, were significantly associated with age, indicating more aggressive disease in older ones.
AN ANALYSIS OF HIGHER SECONDARY STUDENTS CHALLENGES WITH CHEMISTRY LEARNING
Authors:   Research Scholar (Reg.No 21112102031003), Department of Chemistry, Kamaraj College, Thoothukudi - 628003, Tamil Nadu, India., B. Suresh , Vanmathi G. ,   Associate Professor, Department of Chemistry, Kamaraj College, Thoothukudi - 628003, Tamil Nadu, India.
Published: November 2024

Every facet of contemporary society is impacted by the benefits and influence of science. In todays society, chemistry is essential to satisfying peoples needs and desires, and it has become a major human endeavor. The basis for all other sciences is chemistry. Learning new information and abilities as well as comprehending the relationships that relate the problems solution to it are the main objectives of chemistry education. The complexity of chemistry instruction at the upper secondary level has increased. This studys primary goal was to identify the difficulties chemistry students have in their studies and offer suggestions for improving their performance in upper secondary school. In the Thoothukudi district of Tamilnadu, India, 200 higher secondary students who were all taking chemistry as one of their subjects participated in the research. The findings showed that higher secondary pupils have more complex comprehension issues with chemistry ideas. Based on the students class level (Standard XI and XII) and location, there was no discernible variation in the challenges they faced when learning physics nevertheless, there were discernible disparities based on the gender.
FASTER AND COST-EFFECTIVE EXTRACTION FREE METHOD FOR SARS-COV2 DETECTION BY RT-PCR
Authors:   Senior Assistant Professor, Department of Microbiology, Coimbatore MedicalCollege, Coimbatore - 641 014., Santhose N. Bharathi , Murali K. Saravana ,   Virus Research and Diagnostics Laboratory (VRDL), Department ofMicrobiology, Coimbatore Medical College, Coimbatore - 641 014., Avinash Divakaran ,   Virus Research and Diagnostics Laboratory (VRDL), Department ofMicrobiology, Coimbatore Medical College, Coimbatore - 641 014., K.R Arunbalaji ,   Virus Research and Diagnostics Laboratory (VRDL), Department ofMicrobiology, Coimbatore Medical College, Coimbatore - 641 014., S.V Satish ,   Virus Research and Diagnostics Laboratory (VRDL), Department ofMicrobiology, Coimbatore Medical College, Coimbatore - 641 014.
Published: November 2024

Background: The World Health Organization (WHO) declared an outbreak of febrile respiratory illness caused by Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) in Wuhan City, China in December 2019. Within the immediate outbreak of three months, the global community was challenged with a devastating pandemic that caused heavy morbidities and mortalities around the globe. The expeditious spread of the virus, challenged the diagnostic laboratories to rapidly develop the accurate molecular diagnostic methods. As SARS CoV-2 assays became available for testing on existing molecular platforms, laboratories devoted unprecedented energy and resources to evaluating the analytical performance of the new tests and in some cases developed their diagnostic assays under FDA-EUA guidance. Aim: This study aims to compare the diagnostic efficacy of the extraction-free method of COVID-19 PCR and the conventional RT-PCR with extraction. Method: To get an accurate view of how an omission of RNA extraction step would perform in a real-world setting, a comparative study was performed using TATA MD CHECK RT-PCR DIRECT (Direct PCR) and LabGun Genomics for Conventional RT-PCR method. Result: From this study, direct RT-PCR correctly identified 92.3% of samples (n = 50) identified positive for SARS-CoV-2 RNA by conventional RT-PCR featuring an RNA extraction. Conclusion: Direct methods may represent a reasonable alternative to meet higher testing demands with low turnaround time as reverse transcription PCR includes traditionally time-consuming RNA extraction and purification procedures.
MITRAL STENOSIS PRESENTATION REVEALING ALARGE LEFT ATRIAL MYXOMA
Authors:   Cardiology Department University Hospital Agadir, Faculty of Medicine & Pharmacy Ibn Zohr University, Agadir-Morocco., Chaib MD Zakaria , Beladel MD Wassim ,   Cardiology Department University Hospital Agadir, Faculty of Medicine & Pharmacy Ibn Zohr University, Agadir-Morocco., El Minaoui MD Mohamed ,   Cardiology Department University Hospital Agadir, Faculty of Medicine & Pharmacy Ibn Zohr University, Agadir-Morocco.
Published: November 2024

Introduction: Cardiac myxoma (CM) is the most frequent benign primary cardiac tumor. Around 75% of myxomas originate in the left atrium 20% arise from the right atrium while the remaining 5% are born from both the atria and the ventricle. Atrial myxomas can result in many symptoms: heart failure, systemic or pulmonary embolism, arrhythmias, and conductive disorders, or also constitutional symptoms (such as fever, and weight loss). It largely relies on the tumors size, location, and architecture. It can obstruct the blood flow, mimicking mitral stenosis. The surgical management is the cornerstone of this entity. Case Report: A 63-year-old female with a past medical history of diabetes and arterial hypertension was admitted to our department for palpitations and acute heart failure symptoms.The physical examination revealed an irregular pulse with a tachycardia of 150 bpm. The blood pressure was at 118/80 mmHg. It also revealed lower limb edema, lung crackles, and ascites with a mitral stenosis murmur. EKG showed atrial fibrillation at 150HR . Transthoracic echocardiography found dilated atriums with a large mass in the left atrium causing mitral pseudo stenosis . Discussion: Myxomas are primary cardiac tumors that originate from multipotent mesenchymal cells. They can occur at any age but mostly between 30 and 60 years. The incidence of myxoma in women is 2 to 4 times higher than in men. Clinically, atrial myxomas vary from asymptomatic especially with small tumor size, to non-specific symptoms (dyspnea, lower limb and pulmonary oedema, angina, syncope, and palpitation) and constitutional symptoms such as fever, fatigue, and weight loss. The diagnosis of atrial myxoma based on its presentation is challenging. echocardiography is usually the modality of choice which helps identify the location of the mass whether itÂ’s intra or pericardial, its size, attachment and mobility. Furthermore, it differentiates atrial myxoma from any thrombus or vegetation. Once a presumptive diagnosis of myxoma has been made on imaging studies, prompt resection is required because of the risk of embolization or cardiovascular complications, including sudden death. Conclusion: Myxoma continues to be a significant challenge for emergency physicians due to its non-specific symptoms and overlap with other conditions. The discrepancy between mild symptoms and the serious consequences the condition carries, necessitates high index of suspicion and thorough investigation to timely diagnose it among a long list of differentials.
Exploring Gumuruh Village's Upcycling Potential Using Creative Innovation To Turn Plastic Waste Into Commercial Products
Authors: Amalia Friska , Simarmata Andriano , Suliastuti Iftika , Azis Baskoro , Sabiella Imanda Dea
Published: November 2024

Plastic waste presents a major environmental challenge worldwide, with improper disposal endangering ecosystems. Upcycling offers a solution by conserving natural resources, reducing carbon emissions, and minimizing waste, all while lowering the demand for new production. Additionally, recycling generates significant economic benefits, particularly by producing high-quality commercial products in sectors like furniture. In Gumuruh Village, Bandung, the community actively participates in recycling efforts, including the processing of organic waste, to create sustainable products. Through the Design Thinking approach and Service Learning, academics and local SMEs collaborate to design and develop products that directly benefit the community.
Multi-source partial discharge pattern recognition in GIS based on Grabcut-MCNN
Authors: Wang Zhen , Fu Hui , Hu Chengbo , Liu Ziquan , Li Yujie , Sun Weihao
Published: November 2024

Partial discharge (PD) surveillance constitutes a pivotal methodology for diagnosing insulation failures in electrical equipment. Enhancing comprehensively the precision of identifying PD anomalies in Gas Insulated Switchgear (GIS) is of paramount significance for ensuring the steady functioning of power grids. This study introduces a novel framework that integrates Phase-Resolved PD Graph Segmentation (PRPD-Grabcut) with a tailored MobileNets-based Convolutional Neural Network (MCNN) to classify GIS-related PD issues. Leveraging image segmentation via PRPD-Grabcut, crucial features are extracted from PRPD diagrams, which then facilitate the construction of the MCNN model. This model employs depth-wise separable convolutions alongside inverted residual architectures to tackle the vanishing gradient dilemma inherent in Deep Convolutional Neural Networks (DCNNs) during GIS PD pattern discernment. Upon the model's subsequent training and validation, empirical evidence illustrates that the PRPD-Grabcut-MCNN hybrid significantly alleviates the computational load and storage requisites of the model, concurrently enhancing the recognition precision and expediting the training process of the neural network. Relative to diverse established lightweight neural network architectures, MCNN manifests superior performance in terms of recognition accuracy, reduced cross-entropy loss, and expedited training duration.
Research on intelligent cutting control technology of transverse moving machine for large cross-section roadheader
Authors: Qin Wenguang , Cheng Kai , Wang Biao
Published: November 2024

With the continuous development of the coal mine industry in our country, the cross-section of the roadway is getting larger and larger. The widely used EBZ series roadheader cannot complete the roadway cutting operation with a large cross-section at one time, so it usually needs to move the equipment left and right to complete all its cutting tasks. This paper studies the intelligent control technology of large cross-section roadway cutting, which mainly solves the positioning and attitude determination technology of roadheader in the large cross-section, and offers an accurate shape-cutting control technology and a path planning technology using a lateral moving machine. This paper proposes to combine the signals of laser sensor and fiber-optic inertial navigation system to form a combined positioning and attitude determination system, so as to make use of the advantages and avoid the disadvantages of their respective systems, and improve the accuracy of roadheader positioning and attitude determination. A swing kinematics model of the cutting arm is established, based on which the precise motion control of the first roadway section cutting and the second roadway section cutting can be realized. A key parameter calculation model of roadheader lateral moving machine is put forward to calculate the operation parameters for roadheader lateral moving machine path planning. Finally, the experimental research on intelligent cutting control technology of large cross-section roadheader is carried out in 12307 intelligent heading face of Wangjialing Coal Mine. The results show that the positioning error of the combined positioning and attitude determination system proposed in this paper is between 50-90 mm in the X-axis direction and between 25-45 mm in the Y-axis direction. The average attitude measurement error of heading angle is between 0.5 and 1.5°. This makes the technology appropriate for engineering use. The studied cutting control system achieves a cutting error of 25-50 mm for the first section, and a cutting error of 40-90 mm for the complete section. The complete section cutting error meets the ±100 mm cutting error requirement required in engineering. The intelligent cutting control technology of the lateral moving machine of the large-section tunnel boring machine studied in this paper can realize accurate cutting of the large-section tunnel of 5.6 meters. The research results of this paper provide a reference for the intelligent construction of heading faces.
Educação Rurbana
Authors: Faria Filho Luciano Mendes de , Pereira Elaine Aparecida Teixeira , Daniel Leziany Silveira
Published: November 2024

Este trabalho tematiza o lugar do rural e do urbano nas pesquisas e nos debates realizados no Centro Regional de Pesquisas Educacionais do Recife (CRPE-Recife) durante a gestão de Gilberto Freyre, ou seja, no período de 1957 a 1969. A pesquisa que resultou neste artigo teve por objetivo compreender como as visões da América Latina presentes na produção intelectual de Gilberto Freyre animaram, ou não, as ações políticas, interpretativas ou reflexivas do Centro Regional de Pesquisas Educacionais do Recife. Em seu desenvolvimento, deparamo-nos com um intenso debate sobre as relações entre o regional, o rural e o urbano no âmbito das políticas escolares e das epistemologias da pesquisa educacional. A documentação mobilizada pertence ao Centro Regional sob a guarda da Fundação Joaquim Nabuco, do Recife, e/ou foi disponibilizada pelo Instituto Nacional do Estudos Pedagógicos, especialmente os Cadernos Região e Educação.
DANÇA DE SÃO GONÇALO DE AMARANTE
Authors: Oliveira Victor Hugo Neves de
Published: November 2024

Este artigo compartilha reflexões sobre a Dança de São Gonçalo de Amarante: espécie de manifestação realizada como devoção a um santo católico conhecido como São Gonçalo de Amarante. Busca-se identificar, a partir dos processos de folclorização, as principais transformações e atualizações estabelecidas no panorama da dança. Para tanto, debate-se as principais diferenças estabelecidas entre a prática da dança ora produzida como pagamento de promessa, ora como ato de representação.
ÉTICA/ESTÉTICA DAS GINGAS
Authors: Domenici Eloisa , Pires de Carvalho Jose Antonio
Published: November 2024

Este artigo discute as aprendizagens do corpo nas rodas e brincadeiras populares, com foco nas relações éticas e estéticas que caracterizam esses ambientes. A proposta é realizar esta reflexão com as experiências dos autores, principalmente de duas maestrias, na Capoeira e no Bumba meu boi. Ao descrever como as aprendizagens corporificadas se desenvolvem nesses ambientes, pretende-se ampliar a compreensão sobre as especificidades dessas rodas/brincadeiras em que o corpo aparece como terreiro. O interesse é endereçar essa questão a partir de dois níveis de leitura interconectados: o primeiro, a formação ética/estética, e o segundo, do ponto de vista sensório-motor e afetivo-cognitivo, remete à consciência corporal. Como discutir estas relações nas rodas de capoeira e nas brincadeiras populares? O que a capoeira e o Bumba meu boi trazem de particularidades para as aprendizagens corporais, consideradas em suas epistemologias próprias? O nosso ponto de vista consiste em argumentar que tudo está interligado, ou seja, a aprendizagem ética/estética nessas rodas e o papel do corpo nesses processos.
Palavras-chave: Capoeira. Bumba meu boi. Aprendizagens. Corpo. Ética/Estética.
A dramaturgia coletiva da peça de teatro Urgente (2016)
Authors: Pedra da Silva Marco Antonio
Published: November 2024

O objetivo deste artigo é analisar a dinâmica coletiva na criação da dramaturgia da peça Urgente (2016), escrita por dois grupos teatrais - Cia. Luna Lunera (MG) e Areas Coletivo de Arte (RJ).  Este estudo apresenta informações sobre o processo de escrita do texto, a criação de sua encenação e a recepção do espetáculo frente à crítica e o público. Para tanto, analisei o programa da peça, fotos, gravação de vídeo, projeto de montagem e críticas publicadas em jornais de Belo Horizonte, Rio de Janeiro e Brasília. Além disso, busquei outras informações sobre o espetáculo ao entrevistar os atores Marcelo Souza e Silva, Cláudio Dias e Zé Walter Albinati, presentes no elenco.
E O MITO SE FEZ CARNE, E PERFORMOU ENTRE NÓS
Authors: Medeiros Éric Inácio de
Published: November 2024

Neste trabalho, buscamos desvelar algumas camadas acerca do conceito de mito, na contramão de uma visão fixa, universal e arquetípica que, muitas vezes, a ele é direcionada, refletindo acerca de sua contribuição para as artes da cena, através do seu caráter performativo, bem como da importância de suas reescrituras na cena contemporânea. Neste sentido, utilizamos Heidmann (2011; 2014), Dupuis (2003), Martins (2003), Rufino (2019) e Santos (2009) para compreendermos o mito como potencialidade discursiva, observando a sua dinamicidade dentro da cultura africana e afrodiaspórica.
Roda e Cypher
Authors: Barner Viola Luise , Machado Lara
Published: November 2024

O artigo “Roda e Cypher - Capoeira e Breaking” propõe desenvolver um diálogo entre os espaços onde acontecem as culturas da capoeira e do Breaking, a partir das vivências das autoras do texto. Com base nos diversos encontros, entre rodas e cyphers, essa escrita relata experiências, conta histórias, desenvolvendo pensamentos para a dança em suas movências, jogos, lutas, disputas e criações.
SONHO JUNTO, COMIDA COMPARTILHADA
Authors: Mitkiewicz de Souza Luciana
Published: November 2024

O artigo propõe uma reflexão sobre o conceito de teatro em comunidades no Brasil em uma perspectiva comparativa entre o chamado teatro de vizinhos nascido na Argentina e algumas práticas brasileiras, especificamente, o trabalho de dois grupos teatrais cariocas, a Cia Marginal e o Coletivo Bonobando, para perceber aproximações e distanciamentos entre poéticas, processos e procedimentos artísticos aqui e lá observados, e as relações que estes grupos tecem entre arte e política, corpo e território.
A CONDIÇÃO RITUAL DO ACONTECIMENTO CARNAVALESCO:
Authors: Da Cruz Souza Marco Aurélio , Silva de Amorim Jesus Thiago
Published: November 2024

O presente texto se propõe a discutir ideias que assumem e compreendem a condição ritual inerente ao acontecimento carnavalesco. A partir de uma articulação conceitual entre pensadores do campo da cultura, debatemos algumas características do fenômeno carnavalesco de rua, sobretudo os desfiles de escolas de samba do carnaval brasileiro, com vistas a problematizar as perspectivas de inversão e extraversão que se articulam em tal contexto popular, atentando-se a relações e aspectos ligados com sua corporeidade e gramática gestual próprias.
Engrenagens para a construção de uma releitura cênica a partir do cordel “O Romance do Pavão Misterioso”
Authors: Sátiro André
Published: November 2024

Este artigo apresenta os processos de construção do espetáculo “Misterioso”, que propõem uma releitura da literatura de cordel “O Romance do Pavão Misterioso” para crianças e adolescentes. A pesquisa dialoga com leituras em torno do conceito de ator-narrador sob a perspectiva da pesquisadora Nara Kaiserman, colaborando com o processo de construção da personagem dos atores em cena, resultando assim, em caminhos que levaram o grupo a trabalhar uma atualização da narrativa. O projeto surge dentro da Universidade Federal de Campina Grande e logo ganha as salas de aulas das escolas municipais da cidade de Campina Grande, na Paraíba.
EM EBULIÇÃO:
Authors: Valéria Vicente Ana
Published: November 2024

Entendendo a festa como espaço-tempo de construção e transmissão de conhecimento, apresentamos uma síntese fruto de um trajeto de pesquisa por dentro do carnaval de Olinda. Este trajeto errante acompanhou foliões que têm na cultura do frevo um modo de brincar guiados pela prática dessa dança vigorosa e pulsante. Para isso, localizamos a investigação somática como método de pesquisa e o campo da dança como área de produção de conhecimento. Apresentamos uma compreensão do carnaval de Olinda como uma expressão cultural que permite ao individuo a possibilidade de renovação energética, uma transformação psicofísica com impacto nos modos de ser e de estar. Identificamos a construção dessa renovação através de tecnologias do carnaval, que proporcionam experiências que favorecem o encontro e a transformação do organismo.
Palavras-chave: Energia, decolonial, dança, prática como pesquisa.
Anti-Alzheimer's Disease Target and Beneficial Effect in Formononetin
Authors: Xiao Hai , Nong Yuan , Huang Yiqing , Qin Xingyue , Liu Meizhen , Qin Lixiu , Yang Bin
Published: November 2024

Introduction:

Alzheimer's Disease (AD), a common neurodegenerative relevance of
dementia, is spreading in the world. Hitherto, the pharmacological treatment for AD is prescribed
limitedly in clinical application. Recently, it has been found that naturally occurring extracts
possess promising anti-neurodegenerative properties, including AD.

Method:

Our previous study indicated that formononetin (FMN) exerts the anti-AD benefits
based on bioinformatics analysis. However, the experimental validation for bioinformatics findings
has not been conducted. In this study, we primarily applied the molecule docking analysis
to ascertain the pharmacological targets, including cytochrome P450 19A1 (CYP19A1). Transgenic
AD mice were used to validate the bioinformatics findings in vivo experimentally. Molecular
docking data showed that FMN acted directly on CYP19A1 target protein with effective
binding sites and potent combining affinity/energy.

Results:

Meanwhile, FMN intervention contributed to an increased trend of body weight in
transgenic AD mice reduced hippocampal expression of Aβ1-42, and elevated content of
CYP19A1. Additionally, FMN intervention showed reduced terminal deoxynucleotidyl Transferase
dUTP Nick-End Labeling (TUNEL) expression and increased CYP19A1 and Ki67 expressions
in hippocampal sections of transgenic AD mice.

Conclusion:

Collectively, FMN may be used for the prevention of AD, and the pharmacological
activities are possibly related to reducing Aβ1-42, and TUNEL expressions to increase Ki67
and CYP19A1 activities.