bluuebunny/crossref_metadata_2025 huggingface dataset:
OS CONHECIMENTOS PRÉVIOS E SUAS IMPLICAÇÕES NA FORMAÇÃO CIENTÍFICA DE ACADÊMICOS DO CURSO DE AGRONOMIA DA UFSM
Authors: Pauli Andriele Maria , Lüdke Everton
Published: January 2022

O ensino por meio dos conhecimentos prévios dos alunos é uma ferramenta elementar quando se trata do processo de aprendizagem de Física. Além disso, a inclusão do estudo dos conteúdos de Física no contexto da prática profissional tem se revelado motivadora e promissora aos olhos dos estudantes, uma vez que o processo de ensino e aprendizagem tem permitido uma vivência mais concreta e significativa dos conteúdos propostos em sala de aula. Este artigo apresenta alguns dos indicadores que corroboraram com a afirmação anterior a partir do contexto e das características presentes em uma turma de estudantes do segundo semestre do curso de Agronomia da Universidade Federal de Santa Maria (UFSM). A partir da análise crítica, investigou-se como se dá a relação entre os conhecimentos prévios, as atitudes, a aprendizagem dos conceitos de Física e os estudantes. Os dados foram obtidos por meio da implementação de dois questionários, sendo realizada, posteriormente, a Análise de Conteúdo de Bardin e a estatística descritiva quando pertinente. Verificou-se que a familiaridade do estudante com os conceitos e a prática agrícola contribuiu no processo de aprendizagem dos conceitos físicos. No entanto, diante do elevado nível de desconhecimento dos conteúdos de Física, principalmente dos conteúdos relacionados à Óptica e Física Moderna e Nuclear, constatou-se a necessidade urgente de reestruturação da prática docente e disciplinar de forma que o ensino de conceitos fundamentais em Física tornem-se potencialmente significativos para os estudantes.
HOTEL PARA INSETOS
Authors: Wommer Fernanda Gabriela Bitencourt , Loreto Elgion Lúcio da Silva
Published: January 2022

O presente relato de experiência refere-se de uma atividade didática desenvolvida em uma escola do campo, através das atividades não presenciais no ano de 2020, durante a pandemia de COVID-19. Com a intenção de promover a aprendizagem de conceitos científicos que valorizem e preservem o meio ambiente, a atividade didática possui o objetivo principal de engajar os alunos na criação e construção de um hotel para insetos, desenvolvendo habilidades e apresentando conceitos relevantes no estudo de Ciências do Ensino Fundamental, buscando superar os obstáculos encontrados durante o ensino remoto. Para isso, a atividade didática foi proposta aos 20 alunos matriculados do 6º ao 9º ano de uma escola de ensino público, durante o período de 15 dias. Este trabalho emprega a abordagem de estudo de caso e utiliza como estratégia as Metodologias Ativas de Aprendizagem. Avaliamos que os resultados obtidos nesta atividade didática são positivos e promissores para o Ensino de Ciências, no qual Metodologias Ativas de Aprendizagem, como a “Hands on” e a “Aprendizagem Colaborativa” possuem a capacidade de unir a teoria e a prática favorecendo a aprendizagem e tornando o ensino mais prazeroso e eficaz. Desta forma, a atividade didática “Hotel para Insetos” possui o potencial de contribuir para o aumento das entregas das tarefas durante o ensino remoto, despertar o interesse dos alunos sobre os insetos e sobre a sua importância ambiental.
CURSO ONLINE SOBRE “APRENDER E ENSINAR POR PROJETO” COMO AÇÃO FORMATIVA PARA OS RESIDENTES DE QUÍMICA DURANTE A PANDEMIA
Authors: Pinto Monteiro Ercila , Gomes da Costa Ademir Victor
Published: January 2022

O curso online sobre “Aprender e Ensinar por Projeto” foi oferecido na modalidade de extensão aos participantes da Residência Pedagógica (RP), subprojeto Química, da Universidade Federal do Amazonas – UFAM entre os meses de Outubro a Dezembro de 2020. A finalidade de oferecer um curso online foi de compreender de que maneira o curso online “Ensinar e Aprender por Projeto” poderia se apresentar como ação formativa na residência pedagógica. Dessa forma, os residentes realizaram várias atividades na plataforma sala de aula, sendo incentivados a se apropriar da teoria “Aprendizagem baseada em projetos” construindo uma rotina de pensamento sobre o processo de ensino-aprendizagem em colaboração a teoria de David Perkins. No final do curso, os residentes produziram vários projetos coletivos e temáticos a partir da teoria da “Aprendizagem baseada em Projetos” – ABP, cuja autenticidade foi identificada pela proposta de ensino inovador, interessante, com diversidade de avaliação, problematizado e próximo de situações reais. Os resultados mostram que 90% dos residentes tiveram as suas expectativas alcançadas, os quais destacaram várias características da ABP, principalmente, o protagonismo, a autonomia e a inovação como ação necessária a prática da ABP. Além disso, destacaram a importância de se distanciar do ensino tradicional fomentando novas propostas de ensino, principalmente, com a diversificação das avaliações que se apropriam no decorrer do curso.  Nessa circunstancia, pode-se afirmar que uma ação de extensão quando bem planejada pode também garantir os propósitos curriculares de formação dos professores.
FORMAÇÃO NA ÁREA DE ENFERMAGEM: DISCUSSÃO A RESPEITO DE ABORDAGENS METODOLÓGICAS VIA ARCO DE MAGUEREZ
Authors: Fontoura dos Santos Enilda , Lindemann Renata Hernandez
Published: January 2022

Este trabalho objetiva mapear publicações no campo da enfermagem, que adotem a metodologia da problematização utilizando o Arco de Maguerez. Trata-se de uma pesquisa bibliográfica do tipo “estado do conhecimento” e teve natureza qualitativa. Os dados empíricos foram obtidos no Portal de Periódicos da CAPES e analisados através da análise de conteúdo (BARDIN, 2011). As pesquisas apontaram que o uso da metodologia da problematização, através do Arco de Maguerez na área da saúde, contribuem para a formação de um profissional crítico-reflexivo, humano e transformador. Apesar disso, os trabalhos analisados não se referem ao ensino técnico em enfermagem, sendo, na sua maioria, voltados para a graduação de enfermagem. Portanto, sinaliza-se a carência de pesquisas sobre a formação do profissional técnico em enfermagem, que abordam a metodologia da problematização através do Arco de Maguerez. Concluiu-se que a metodologia da problematização através do Arco de Maguerez pode ser utilizada e desenvolvida em diferentes níveis e modalidades de ensino.
Impact of Living in Different Altitudes on Intracytoplasmic Sperm Injection (ICSI) Outcomes for Infertile Couples in Southwestern Region of Saudi Arabia, a Retrospective Study
Authors: Eskandar Mamdoh , Alasmari Wardah , Idris Fawaz , Nadwi Huda , Radwan Enshrah , Mubarak Tahir , Eskandar Rayan
Published: January 2022

Objective: The aim of this study was to determine the effect of different altitudes in the Southwestern region of Saudi Arabia on ICSI outcomes, fertilization rate, embryo quality, pregnancy rate, and miscarriage rates for infertile couples. Materials and Methods: This is a retrospective study on 551 infertile couples carried out in the Assisted Reproductive Technology unit at the Maternity and Childern Hospital in Abha, Saudi Arabia between 2018 and 2019 to compare ICSI outcomes in different altitudes. Low altitude (205 patients), mild altitude (86 patients) and high altitude (260 patients). Main result measurements: fertilization rates, embryo quality, clinical pregnancy and miscarriage rates at different altitudes. Results: The data showed that there were no significant differences (P>0.67) in fertilization rates and the number of good-quality embryos between different altitudes. Importantly, clinical pregnancy rates were similar between groups and there was no significant difference in the miscarriage rates between high, mild and low altitudes. Conclusions: This study demonstrates that there is now increased risk of miscarriage or low pregnancy rates with different altitudes in Southwestern region of Saudi Arabia. This suggests that altitude changes has no obvious risk on pregnancy rate and pregnancy outcome.
Comparison of Pipelle and Hysteroscopy with D&C in Postmenopausal Patients
Authors: Piriyev Elvin , Schiermeier Sven , Römer Thomas
Published: January 2022

Objective: The aim of the study is to compare the pipelle method and hysteroscopy with D&C in postmenopausal patients Methods: In this prospective study, only those postmenopausal patients with postmenopausal bleeding and/or with a sonographically highly developed endometrium who were referred for hysteroscopy with D&C were included. A total of 92 patients were included in this study. Before each procedure, patients were explicitly informed about the study and gave consent. On the condition of anonymity of personal data (surname and first name, date of birth) and after signing a special informed consent form, the patients were allowed to be included in the study. The study was performed as a double-blind study. The obtained histologies (from pipelle and D&C) were sent separately to the same pathologist. Results: The group with malignant and premalignant findings has a central role in our study. After evaluation of the histologically malignant findings from the pipelle and the D&C, the sensitivity of the pipelle in our study was 82%. Conclusion: Endometrial biopsy is an important step to exclude endometrial carcinoma in postmenopausal bleeding. The aim is to minimize the burden and invasiveness of the procedure while maintaining a high degree of diagnostic certainty to avoid unnecessary invasive surgery. The pipelle sampling can be used as an outpatient method without anaesthesia during routine examination. Our study shows that this method of sampling is a safe, accurate and cost-effective outpatient procedure with high sensitivity for the detection of endometrial carcinoma.
Role of MRI in Pre-Operative Assessment of Patients with Advanced Ovarian Cancer Candidate for Cytoreductive Surgery, A Brief Review
Authors: Tajiknia Vida , Hassani Sara , Seifmanesh Hamidreza , Afrasiabi Ali , Hosseinpour Hamidreza
Published: January 2022

When it comes to gynecologic cancer, ovarian cancer with no doubt is the deadliest and most challenging. The reason often falls into the late presentation, in fact the clinical symptoms are not prominent until the disease is disseminated In patients with advanced ovarian cancer cytoreductive surgery procedure is the key element in treatment plan. One of the best tools to predict successful and complete cytoreductive surgery is using prior imaging. Magnetic resonance imaging is one of the newly described imaging modality for advanced ovarian cancer patients selected for cytoreductive surgery. Here we discussed the application of MRI in advanced ovarian cancer underwent cytoreductive surgery.
Lipid profile an important risk factor in patients with ovarian tumors: a meta-analysis
Authors: Ionut Faur Flaviu , Clim Adelina , Nati Ionel , Dobrescu Amadeus
Published: January 2022

Introduction: In the literature ovarian tumors are knowed to be one of the most deadliest gynecological malignancies [1-4]. In US this type of malignancy represents 2.3 % of all cancer-related death and about 4 % of all new cancer cases among women. There are several studies that have reported the role of lipid profiles and it’s role in ovarian tumorigenesis. Fatty acids are essential for cancer cells progression[4-8]. In our study we investigated the true differance in circulating lipid profiles (total cholesterol TC, triglyceride TG, high-density lipoprotein cholesterol HDL, low density lipoprotein cholesterol LDL) among patients with and without ovarian tumors (OT) using a meta-analytical approach. Mehods: The meta-analysis was conducted using the MOOSE guidelines. PubMed, EMBASE and Cochrane Library were extensively searched ( with a period of publication restriction between 2007 and 2019) to indetify published studies using the following keywords: “ total cholesterol ”, “high-density lipoprotein”, “ triglycerides ”, “ low-density lipoprotein ”, “ ovarian cancer”, “ ovarian tumor ”, “ lipid profile ”. The search methodology is shown in Fig. 1 and all references of retrieved articles were searched manually. Results: Seven studies, involving 1542 OT cases and 2195 non-cases of OT were included in this meta-analysis and I² statistics ranged between 97 and 99%. Mean circulating TC and HDL were significantly lower among OT cases compared to non-OT cases (P<0.04 and P<0.005). Conclusion: There is a modest significant association between circulating HDL and risk of ovarian tumor but it is crucial to elucidate the implications of HDL in tumor manifestations and growth.
Psychiatry In-patient Substance Profile Changes in COVID year 2020 from 2019 in a Teaching hospital of Eastern Nepal
Authors: Shakya Dhana Ratna
Published: January 2022

Subsequent time, after declaration of COVID-19 pandemic, witnessed variable changes in various aspects due to COVID circumstances around the globe. We report and reflect here over the observation regarding substance use and use disorder scenario in initial COVID year 2020 in reference to 2019 (year preceding COVID-19 pandemic). It is an observation in psychiatry in-patient service of a teaching hospital of eastern Nepal. There were 420 (284 male, 136 female) and 279 (194 male and 85 female) admissions in 2019 and 2020 respectively. The most striking and significant change was seen for Nicotine, both overall and use disorder-wise. Over all, the proportion increased for Nicotine (34.05 to 48.03%) and Cannabis (16.67 to 17.92%) whereas decreased for Alcohol (38.33 to 31.18%), Opiote (7.62 to 6.81%), Benzodiazepine (6.43 to 5.73%) and other substance (0.71% to nil) among the in-patients in 2020. Categorically, both the Use and Dependence syndrome (ICD-10) increased for Nicotine (8.81 to 21.86%% and 25.24 to 26.17%) and Cannabis (10.71 to 11.47% and 5.72 to 6.45%). Proportion of Alcohol use and Harmful use decreased whereas Alcohol dependence increased, Opiote use increased whereas Harmful use and Dependence decreased, Benzodiazepine use and Dependence decreased and other substances decreased too. The observation shows various changes in the pattern of substance among the psychiatry in-patients which indicates the need for some strategic and policy changes to tackle this pandemic situation.
The Association between Depression and Suicidal Ideation A Systematic Review and Meta-Analysis
Authors: Tesfaye Tegegne Kaleab , Tesfaye Tegegne Eleni , Kassa Tessema Mekibib , Semeon Bagajjo Wosenyeleh , Rike Muse , Tadele Abebe Alelign , Bifato Berhanu
Published: January 2022

The purpose of this meta-analysis was to assess the association between Depression and suicidal ideation. We use data from six studies to do a meta-analysis. We applied the random-effects analytic model and calculated a pooled odds ratio. The combined effect size showed that odds of suicidal ideation among people with Depression is 4.88 times higher than those peoples without Depression (ORMH 4.88 95%CI 2.04, 11.72) Test for overall effect: Z = 3.55 (P = 0.0004) Heterogeneity: Tau² = 1.11; Chi² = 100.97, df = 5 (P < 0.00001); I² = 95%. The magnitude of suicidal ideation among people with Depression is 46.39% (528) and peoples without Depression is 17.79 % (315) from the total, 39.13 % (1138) is depressed and 60.86% (1779) not depressed. The overall proportion of Suicidal Ideation among the included studies is 28.98 % (843). The total number of study subjects included in our systematic review and meta-analysis is 2908.
Food Preferences and Dark-side Personality Traits
Authors: Furnham Adrian
Published: January 2022

This study investigated the association between a variety of taste preferences and the Dark Triad personality traits. We noted over twenty studies that linked personality to taste/beverage preference and experience. In this study just under 200 participants completed a personality and food preference questionnaire. Results demonstrated that dark side traits accounted for around ten percent of the variance in tastes, including bitter and sweet as well as alcohol and coffee strength preferences. For a number of the taste preference measures sensation seeking and harm aversive personality traits were particularly influential in determining taste preferences. Limitations and directions for future research are discussed.
Localisation Buccale Secondaire D’un Carcinome Renal
Authors: Boumendil Ikrame , Sefrioui Taha Ismail , Ait Taleb Hajar , Nitassi Sophia , Oujilal Abdelilah , Essakalli Leila
Published: January 2022

Renal cell carcinomas are tumors known for their metastatic potential. The lungs, the lymph nodes, the lungs, the spleen, the adrenal gland and the cervix remain the metastatic sites of predisposition. The symptoms of metastatic lesion may be due to the initial manifestation of renal malignancy. We report in this work a buccal localization of metastases from renal cell carcinoma to clear cells in a patient aged 65 years or less in our department of otolaryngology and cervical-facial surgery.
Clinical Value of Size, quadrant, and Hormonal Status in Predicting Axillary Node Metastasis in Early Clinico-Radiologically Negative Indian Breast Cancer- A Hospital Based Prospective Observational Study
Authors: Heroor Anil , T.P Yadhukrishnan , Rahman Ziaul , Vanan Arul , Singhavi Hitesh
Published: January 2022

Background: Sentinel lymph node biopsy (SLNB) is standard of care in clinico- radiologically negative axilla in early breast cancer case. It’s an oncologically safe alternative to Axillary lymph node dissection (ALND), however factors predicting sentinel node metastasis in Indian population is lacking. Methods: A prospective observational study which recruited 80 patients with breast cancer who underwent SLNB with or without ALND, with evaluation of predictive factors including size, type and quadrant , hormonal status of breast this characteristics were prospectively analyzed to predict the axillary metastasis and need of SLNB . Result: Mean age of the patients included in our study was 52.4 years. On univariate analysis, size (p<0.013), upper outer quadrant (UOQ) (p<0.038), central quadrant (CQ) (0.07) were significantly associated with axillary node metastasis in T2 tumors. While on multivariate analysis, UOQ (P<0.009), CQ (p<0.02) metastasis were associated with axillary node metastasis in T2 tumors. Overall sensitivity, specificity, positive predictive valve (PPV) and negative predictive valve (NPV) of SLNB in predicting axillary node status was 77.59%, 100%, 100% and 62.86% respectively. The overall accuracy was 83.7%. Conclusion: Upper outer quadrant, central quadrant and size of the tumors are important prognostic factors to predict axillary node metastasis without the need of sentinel node biopsy in early breast cancers.
Open Surgical Hip Dislocation for an Acetabular Osteoid Osteoma - A Case Report
Authors: J. Prusick Parker , D. Jones Steven , Roberts Jesse , Donaldson Nathan
Published: January 2022

Osteoid osteoma is a benign tumor that accounts for roughly 10-12% of all benign bone forming tumors. This tumor generally occurs within the first three decades of life and occurs more commonly in males. This lesion is painful and is generally worse at night and has relief of symptoms with the use of NSAIDs. Osteoid osteoma is characterized by the production of osteoid surrounded by a rim of sclerotic bone. These lesions most commonly occur in long bones such as the proximal femur, however they can occur anywhere. Rarely, as with our patient, have these lesions been reported in the acetabulum.
Simultaneous Bilateral Hip Fractures in an Elderly Patient in the Absence of Bone Disease: A Case Report
Authors: Ayman Habis Ahmed , CA Wood Gavin
Published: January 2022

Case: Eighty-three years old female patient who sustained a simultaneous bilateral hip fractures after a mechanical fall. The bilateral nature of the problem was not appreciated by the emergency team and was found after the orthopedic consultation. The patient underwent a single stage bilateral cemented bipolar hemiarthroplasty without perioperative complications. Conclusion: Simultaneous bilateral hip fractures in elderly are not commonly encountered after a low energy mechanism but early recognition of this diagnosis is important to optimize perioperative management. Having bilateral cemented stems did not lead to any significant cardiopulmonary complications as can often be concerned with so called cement syndrome.
Bowel Evisceration Following Attempt at Umbilical Vein Catheterization in a Neonate: A Case Report
Authors: Kevin Emeka Chukwubuike
Published: January 2022

catheterization of the umbilical vein provides a quick vascular access in neonates. It is a relatively easy procedure routinely performed in neonatal intensive care units. However, this procedure may come with lots of complications. We report a rare complication of bowel evisceration from the umbilicus following an attempt to catheterize the umbilical vein. This complication may be prevented by meticulous dissection and avoidance of probing of the umbilical vein during umbilical vein catheterization.
The Effective Management and Outcome of Hand Burns
Authors: Joseph Subin
Published: January 2022

Burns is a common public health problem and these injuries can be accidental, suicidal or even homicidal in nature. Hands being the most active part of the body, are often involved in burns. Hand burns represent three percent of body surface area, and are involved in more than 80% of all severe burns. Hand burns predominantly affect young adults and therefore have serious social and financial implications. The hand is one of the most frequent sites of burns scar contracture deformity. The deformities and contractures result in lifelong physical problems and affects the normal functioning of the person.
Alcohol Drinking Patterns and Contributing Factors among Medical Students, a Systematic Review
Authors: J A Sheehama , H J Mbangula , L N Lukolo
Published: January 2022

Background:The use of Alcohol has become an important public health concern with a variety of negative consequences, it is important to understand the variables that may be risk factors for this phenomenon. Further, university students represent a group of individuals who have unique drinking patterns and different risk factors and concerns related to problematic drinking than the population in general. Legal substances like alcohol accounts for the vast majority of negative medical, economic, and social impact. Although alcohol use occurs across many age groups, young adults aged 18–24 years show the highest rates of alcohol use and have the greatest percentage of problems drinkers (Kandel & Logan, 1984). Namibia is ranked fifth on the African continent in terms of annual alcohol consumption with the average Namibian consuming 9.62 liters of alcohol per year (WHO 2011). This review addresses problematic drinking and the variables associated with it for medical students. The purpose of this systematic review is to compare the perception and attitude of alcohol consumption among medical students and weigh the factors associated with drinking habits. Methods:A qualitative and quantitative systematic review of article from multiple search engines. Five articles were within the inclusion criteria thus appraised and reviewed for this paper. The common study method used was cross sectional, with varying sample sizes. Commonly, the use of self-assessment questionnaires and objective AUDIT C and CAGE score evaluation were used frequently between these articles. Results:The review showed that there are multiple factors that influence the use of alcohol among medical students. Personal factors such as a new found sense of independence, peer pressure, inability to handle academic stressors. Socio-economic factors include high tolerance of alcohol use in the communities and monthly expenses. It was also noted that the use of alcohol in medical students is higher than the average university student. A highlighted noted is that the use of alcohol is much higher among male than female medical students. Conclusion:Findings suggested that the perceptions of alcohol use is depended on multiple factors majority being academic perceived stress. It is also noted that continuation of these maladaptive coping mechanisms may lead to dysfunction in the future. The findings of systematic review are limited by the number of articles appraised and reliant on the information provided by the authors.
Covid-19 Vaccine Hesitancy in Nursing Home Staff and the Need for Ongoing Education and Vaccine Access
Authors: Susheela Ammu Thampi , Mahajan Dheeraj , Porter Lori
Published: January 2022

Objective: To study vaccine hesitancy among health care workers who provide direct care in nursing homes and long term care facilities which cater to the most vulnerable population of the community. Design: This is a cross sectional cohort study Setting and participants: The study was conducted on the front line healthcare workers who work in long term care facilities. Methods: A nationwide survey was conducted on the certified nurse assistants on November 16th 2020 which reached 7000 survey recipients. Results: Out of 7000 survey recipients, 3119 responded (45% response rate). There was 71.6% (2,233) negative response about taking the covid19 vaccine due to lack of trust and education of information Conclusions and implications: Our study concluded that the vaccine hesitancy is high among the health care workers of long-term care facility and that ongoing education and interactive dialogue with certified nurse assistants and ongoing access to vaccine is critical as the willingness improves.
Ozone Therapy for Remaining Symptoms after covid Infection in Male Patients
Authors: Alp Hayriye
Published: January 2022

At the end of March, the total number of cases in China, where 3318 people died, is 81.589. The countries with the highest number of approved cases are America (244 thousand), Italy (115 thousand) and Spain (112 thousand), respectively. In Italy, where the largest number of people died, 13 915 people died15 According to the WHO statement on March 3, 2020, the global fatality rate is 3.4. Determination of seasonal respiratory virus or bacteriological factor in samples taken in the patient according to the possible case definition does not rule out the presence of SARS-CoV-2. Patients who received conventional covid treatment in 2021 were included in the study. As exclusion criteria, patients with favism disease and over 100 mg of salicylic acid treatment, and those with ozone and citrus-allergy were excluded from the study. After the informed consent form was signed by the patients, the dose of gamma was increased by 10 in weekly sessions, starting from 10 gamma. major autohomeopathy was applied. The ozone therapy dose was terminated at 40-45 gamma. Peripheral nodular ground glass densities were found in both lung parenchyma in the computed tomography findings of patients receiving Covid-19 treatment before ozone therapy. It was reported in accordance with high-grade thorax computed tomography findings in terms of coronavirus infection. While the patient's complaints decreased after the 3rd session of major autohomeopathy treatment, it was determined that the symptoms decreased a lot in the 5th session.
Review of Cooperative health in the COVID-19 era
Authors: Lirios García , Hernández-Valdés Jorge , Sánchez-Sánchez Arturo , Espinoza Morales Francisco , Carreón Guillén Javier
Published: January 2022

The governance of migratory flows, understood as a system of co-management co-responsibility between institutional and private, political and social actors with respect to their identity and occupational health is addressed in the present non-experimental, exploratory and cross-sectional work with a non-probabilistic sample selection of 100 former migrants from central Mexico. From a structural model seven factors were established regarding framing, demands, resources, risks, opportunities, capabilities and employment. Based on the literature consulted, the limits, scope and lines of research aimed at deepening the effects of the variables and factors in an intercultural scenario are noticed.
Clinical Improvement of Cervical Disc Herniation 24 hours after a Single Oxygen-Ozone Injection
Authors: Kafrouni Hazem
Published: January 2022

Oxygen-ozone therapy is a minimally invasive treatment for disc herniation, compared to surgery, which uses the beneficial biochemical properties of a gas mixture of ozone and oxygen. A satisfactory efficacy is usually obtained within one month after the injection. We assessed the therapeutic outcome of a single injection of oxygen-ozone in a symptomatic patient with C5-C6 cervical discal herniation with compression of the nerve roots. He experienced immediate pain relief seconds after the injection, and neuro-imaging improvement 24 hours afterwards. To our knowledge this is the fastest improvement ever reported in literature.
Evaluation of the Effect of COVID-19 Pneumonia on Kidney Function
Authors: ARSLAN Gürcan
Published: January 2022

Background: Severe acute respiratory tract infection, pneumonia, kidney failure, and multi-organ failure may develop in cases that result in death due to COVID-19. It is emphasized that the awareness of healthcare professionals about kidney functions should be increased in cases of COVID-19 pneumonia. Quick and effective steps can be taken in the treatment of COVID-19 pneumonia with the controlling approach of nurses to changes in kidney functions. Method: This study was carried out retrospectively to evaluate the kidney functions of patients diagnosed with COVID-19 pneumonia who were hospitalized in the pandemic hospital. Hospital and nurse observation files of 120 patients who were introduced to COVID-19 pneumonia between 1 May and 30 November 2020 were examined. Categorical data were described as continuous data as median with interquartile range (IQR) and percentages (%). Results: In total, 30 patients (25.0%) required mechanical ventilation, Overall, 39.1% (47) developed acute kidney injury during hospitalization, out of which 10.8% reached stage 1, 15.0% reached stage 2, and 13.3% reached stage 3. Dialytic support was required for seven (17.1% of all patients). COVID-19 pneumonia patients had higher levels of aspartate aminotransferase (AST) (55.02±58.04), alanine aminotransferase (ALT) (74.07±140.94), lactate dehydrogenase (LDH) (483.48±477.51), C-reactive protein (CRP) (88.02±72.17), D-dimer (1023±1548.01), procalcitonin (3.70± 6.52). In addition, a proportion of COVID-19 pneumonia patients but no non-COVID-19 pneumonia patients had abnormally increased AST (10.0-274.0), ALT (7.0-854.0), LDH (164-3547), CRP (5.10- 310.90), D-dimer (151-6212), procalcitonin (195-433). SpO2 of COVID-19 pneumonia patients had 78-97%, patients who need dialysis treatment due to pneumonia, follow-up coagulation profile (Procalcitonin, LDH, D-dimer), liver-renal function (ALT, AST, Creatine, Urea, Albumin), assessing signs of DVT and psychological support. 89 patients (74.2%) received corticosteroid, 73 patients (60.8%) received expectorant, 61 patients (50.8%) received vitamin C or B complex, 110 patients (91.7%) received anticoagulant and 73 patients (60.8%) received antibiotics. All of the COVID-19 pneumonia patients received the antiviral drug. Conclusion: As the disease progresses, differences in laboratory results and radiological findings may indicate that some complications have developed. COVID-19 pneumonia draws attention with liver function tests such as AST / ALT, LDH, infection markers in the blood, and the high rate of coagulation factors such as PCT and D-dimer during the hospital stay. The fact that these elevated values ​​may cause necrosis in the kidneys also brings about the truth. Careful monitoring of laboratory findings such as elevation of AST / ALT, LDH, PCT, and D-dimer in patients who develop pneumonia due to COVID-19 may provide early action for kidney damage.
Satisfaction and Experience of Palliative Patients with 24/7 Hotline Service During the COVID-19 Pandemic in Saudi Arabia
Authors: Ayed Alshammary Sami , Assiri Yahya , AlRasheed Reema , Abuzied Yacoub , Abelati Mahgoub Igbal , Alqumizi Khalid
Published: January 2022

Background: The COVID-19 pandemic prompted a number of shifts on healthcare. Conventional face-to-face visits were shifted during lockdown to virtual ones. Palliative care (PC) virtual visits have had high satisfaction rates, especially with patients in remote areas. Due to a number of factors, further studies are needed to develop tools that can be helpful and cost effective in improving patient’s quality of life. Objective: Our aim is to learn the main reasons palliative patients in Saudi Arabia sought help via calling the free 24/7 hotline and to discuss the hotline’s satisfaction and effectiveness in solving the palliative patient’s concerns during COVID-19. Methods: A cross-sectional sample analysis was obtained from 214 patients from different regions in Saudi Arabia. A total number of 843 calls were made to the 24/7 PC hotlines from the period of 17 April 2020 to 28 February 2021, shortly after COVID-19 pandemic began. The purpose of the call, the caller's relationship to the patient, the status of the complaint, and the satisfaction rate were collected at the end of the call through a voluntary phone survey. Results: The primary reasons that palliative patients called the hotline were: 30% for medication refills, (n=247), 24.7% for medical complaints, (n=205), 15.8% were for booking a new appointment (n=131). Patients themselves accounted for 27.8% of the callers and patient’s sons/daughters accounted for 51.3%. 85% of patients said that their issue had been resolved by the end of the call and 89% of our sample were happy with the service provided through the hotline. Conclusion: The 24/7 hotline service for PC patients in Saudi Arabia was successful in its application and resulted in a high level of satisfaction among a wide sample of participants. The main reasons palliative patients reached out were to request medication refills, seek assistance with a medical complaint, and to book a new appointment. Our hotline service effectively solved 85% of patients' issues.
Dimensional Meta-Analysis of Trust: Implications for Covid-19 Communication
Authors: Crisanto Gabriel Pérez , García Lirios Cruz , Aguilar Fuentes José Alfonso
Published: January 2022

The objective of this work is to review citizen confidence regarding government action in situations of risk and contingency such as the covid-19 coronavirus pandemic. A documentary, meta-analytic and retrospective study was carried out with a selection of sources indexed to international repositories, considering the period from 2010 to 2020, although the research design limited the results to the research scenario, suggesting the extension of the work towards the relationship between trust and microfinance in the framework of local development.
Clinical pharmacology of lorazepam in infants and children
Authors: Pacifici Gian Maria
Published: January 2022

Lorazepam is a benzodiazepine has antiepileptic activity; it may be administered intravenously, intramuscularly, orally, by intranasal or buccal application and following oral dosing it is well absorbed. In infants, the initial intravenous dose of lorazepam is 100 µg/kg and in children the initial oral and intravenous dose is 50 to 100 µg/kg and the dose varies according to the child age. Lorazepam has been found efficacy and safe in infants and children but it may induce adverse-effects. Lorazepam is a racemate and the R and S enantiomers are conjugated with glucuronic acid in human liver microsomes and the respective Km and Vmax values are 29+8.9 and 36+10 µM and 7.4+1.9 and 10+3.8 pmol/min*mg. Lorazepam interacts with drugs and the interaction may affect the activity or metabolism of lorazepam. The pharmacokinetics of lorazepam have been studied in infants and children and in diseased children. In infants and children the elimination half-life is about 15 hours and it is about 24 hours and about 37 hours in children with severe malaria and convulsions following intravenous and intramuscular administration, respectively. The treatment and trials with lorazepam have been studied in infants and children. Lorazepam freely crosses the human placenta and poorly migrates into the breast-milk. The aim of this study is to review the published data on lorazepam dosing, efficacy and safety, adverse-effects, metabolism, interaction with drugs, pharmacokinetics, treatment and trials in infants and children and the lorazepam transfer across the human placenta and migration into the breast-milk.
Clinical Pharmacology of Fentanyl in Infants and Children
Authors: Pacifici Gian Maria
Published: January 2022

Fentanyl is a systemic opioid related to the phenylpiperidines, it is used in anaesthetic practice and in analgesia and the analgesic effect is about 100 times higher than that of morphine. Fentanyl is highly lipid soluble, rapidly crosses the blood-brain-barrier, and fentanyl concentrations rapidly decline in plasma and cerebrospinal fluid. Fentanyl causes respiratory depression and decreases the heart rate through vagal activation. Fentanyl may be administered intravenously, orally, by transdermal, intranasal or by buccal application and the oral bioavailability is poor. In infants, fentanyl is given for short term use, sustained use, and during therapeutic hypothermia. In children, fentanyl is given intravenously, by transdermal application, or by buccal administration and the fentanyl dose varies with the child age and body-weight. Fentanyl has been found efficacy and safe in infants and children but it may induce adverse-effects and fentanyl causes different effects in infants and children. Following intravenous administration of fentanyl to infants and children, the fentanyl elimination half-life ranges from 208 to 1,266 min and the distribution volume ranges from 1.92 to 15.2 L/kg. Such variability is due to the wide variation of subject’s demographic characteristics. Fentanyl interacts with drugs, the treatment and trials with fentanyl have been studied in infants and children. Fentanyl freely crosses the human placenta and poorly migrates into the breast-milk. The aim of this study is to review fentanyl dosing, efficacy, safety, effects, adverse-effects, metabolism, pharmacokinetics, drug interaction, treatment, and trials in infants and children, and fentanyl placental transfer and migration into the breast-milk.
Paradoxical Malignant Embolism, Brief Review
Authors: M. Weisz George
Published: January 2022

During gestation period the oxygenated maternal blood is transferred to the embryo via the placenta and umbilical cord into the right atrium. It is further transferred through an interatrial shunt to the left atrium, the Foramen Ovale, and distributed to the embryonic body. The foramen is closed after the birth, but remains occasionally patent, permitting embolization through a right to left shunt. This is transferring thrombi, fat, cement and bony spikes, air, and occasionally malignant tissue. This brief review is on the malignant embolization.
Natural Patterns and Magnetic and Mental Processes of Coronavirus Activation and Neutralization
Authors: Bryndin Evgeny
Published: January 2022

For twenty years, humanity has seen the third attempt at the transition of coronavirus to humans. The vaccine has been found, but coronavirus transitions will not stop even with the improvement of medicine. Nobel laureate in medicine Professor Luc Montagnier argues that vaccines may not live up to humanity's hopes of getting rid of COVID-19. Collective immunity for coronavirus has not been developed, repeated infections are more and more common, beds of seriously ill people are not empty, and mortality is running high, no one knows what will happen to all of us. In Israel, where vaccination has long been compulsory, and over 60% of the population, including underage children, have been vaccinated, the incidence is not just declining, but still breaking all records. So, the maximum number of cases here was revealed on September 1 - 16,629, which almost caught up with Russia (18,368 confirmed on the same September 1) with our percentage of vaccinated 26.1% of the number of citizens. At the end of September 2021, morbidity and mortality increase, because it is a system. Based on existing monthly pneumonia mortality statistics over the past 15 years, there are three waves each year. Since September 22, there has been a surge of pneumonia, ARI, and even non-communicable diseases. The second wave comes at the end of December - January, it is usually three times larger than the first. Then around March-April there is a third wave. These three waves exist steadily from year to year, their amplitudes can change, then one will be higher, then the other, they are not absolutely hard on schedule, but they are reproduced regularly in other countries. The first wave of the Spanish pandemic covered the world just at the end of September 1918. The coronavirus was the same. The first wave in America is September 2019, an unexplained surge of pneumonia with a rather high mortality rate, which was written off for smoking e-cigarettes and called "vape." Now they decided to watch the surviving tests of patients, and there - COVID-19. In Europe, it was the same.
21the Wheelchair Project Case Study: Leveraging Collaborative Efforts and Partnerships to Provide Assitive Devices for People Affected by Disability in Thailand and Southeast Asia
Authors: Joseph David Tell
Published: January 2022

Many people affected by disability require assistive devices, particularly mobility aids, in order to live independently and fully integrate into their communities. Throughout the world, numerous methods have been implemented in facilitating the provision of these devices to people affected by disabilities. This case study intends use the Rajanagarindra Institute of Child Development Wheelchair Project, located in Chiang Mai, Thailand, to evaluate the viability and efficacy of mobility-provision programs which adapt wheelchairs and other assistive devices not originally intended for the end user. Programs which must “retro-adapt” equipment, like the Wheelchair Project, rely heavily on medical and mechanical expertise to identify the recipients’ needs and safely modify the device accordingly. By examining the distribution statistics from the Wheelchair Project over its 20 years of operation and the needs of the disability community reported by the National Statistics Office of Thailand alongside a cost-benefit analysis of the declared value provided versus operational cost, this case-study systematically details the scope and financial viability of this approach. While not without constraints, this model succeeds in effectively capitalizing on available resources (both in regard to physical equipment as well as professional expertise) to meet the needs of those affected by disabilities in Thailand and Southeast Asia. Although still limited in size and reach, the Wheelchair Project demonstrably shows its viability and the potential this approach presents given the right circumstances.
Do Patients Correctly Use Steroid Nose Spray? A Patient-Reported Survey of the Nasal Spray Technique and Patient Compliance
Authors: Jamil Waqas , Alahwal Abdullah , Suman Ravinder , Whitwell Megan , Naz Farah , Beech Thomas
Published: January 2022

Background:Correct nasal spray techniqueand patient compliance are the two mostimportant factors in the use of steroid nose spray. Objectives:To find out if patientsuse steroid nasal spray with a correctspray technique and if they are compliant in using the spray. Design: Patient-reported survey Participants: 100 participants (1 excluded) Main outcome measures 1) Nasal spray technique 2) Patient compliance Results: Out of 99 participants included in this study only one patient used steroid nose spray with a completely correct spray technique. 40% of patients received guidance instructions from the prescriber about the spray technique. 70% of patients reported using their spray regularly and 53% of patients were found using the correct dosage of the spray. Conclusions: Wrong spray technique and patient noncompliance is common and can be corrected. This survey emphasizes the importance of giving written and verbal instructions about the use of spray to the patients.
Kimura Disease of the Parotid Gland: Management Approach
Authors: MS Hafeza , Palanisamy Vanitha
Published: January 2022

Here we present a 43-years old Malay man with Kimura’s disease of the right parotid gland. Asian men have a predisposition for this chronic inflammatory disorder of unknown etiology mostly presenting at the head and neck region. The management in dealing with this patient is not straight forward as the presentation mimics a subcutaneous tumor-like mass in which main differential diagnosis includes lymphoproliferative disorders and parotid neoplasm. Moreover, cytological investigation is inadequate, and this necessitates the use intra-operative frozen section prior to tumor debulking. Without proper investigation, misdiagnosis can occur and potentially expose the patient to unnecessary extensive surgical procedures. Here we discuss step by step approach in managing this patient.
Synovial Sarcoma of the Left Palatine Tonsil Case Report and Review of Literature
Authors: A. Magboul Nasir , AlQahtani Mubarak , S. ALQahtani Abdulwahid , Abdullah M Osman Taqwa
Published: January 2022

Synovial sarcoma arises primarily in the lower extremities with a predilection for sites in proximity to large joints, such as the knee. It rarely occurs in the head and neck region, and the tonsil is an unusual site for the tumor, with only eight previously published cases in this anatomical site. 6–10 % of all soft tissue tumors, only 3–5 % arise in the head and neck region, and SS arising in the tonsil is a rare finding, with only eight well-documented cases reported in the English language literature. We describe the histopathological findings of a primary synovial sarcoma of the palatine tonsil arising in a 20-year-old male, with presentation of dysphagia and sleep disturbance.
COVID-19 Associated Rhino-Orbital-Cerebral Mucormycosis - An Institutional Series
Authors: Rana Nishant
Published: January 2022

Invasive fungal infection or mucormycosis is almost always confined to the patients with altered host defenses such as in transplant recipients, diabetics or patients with malignancies. Hypergycemia or uncontrolled diabetes, particularly diabetes acidosis is considered as the strongest and very well known risk factor for mucormycosis. It has spread like fire amongst the active COVID-19 and post COVID-19 diabetic patients. Many studies across the world have established the definitive severity of SARS-CoV-2 infection amongst diabetic patients.
Risk of self-Injury by Patients using Video Otoendoscopes Aimed at home Market
Authors: Jamil Waqas
Published: January 2022

These are powered by USB attachments and can be viewed on mobile phones or home PCs. They are targeted at the home market for examination of ears, nose, and mouths and even some sellers advocate using their use on pets too. They often come with attachments to allow ear cleaning of waand removal of foreign bodies etc. These are available on various online seller websites and can cost as little as £11.
Bioemulsifiers
Authors: Tabassum Khan Nida
Published: January 2022

Bioemulsifier is a poly-anionic and amphiphilic compound which can balance out the hydrocarbon emulsion in water by making an extremely thin layer between the hydrocarbon beads and water. Most extreme focus is acquired when culture media containing 12 carbon-based unsaturated fats are utilized as the carbon source. Bioemulsifier with proficient emulsifying action and low-production cost, meets various prerequisites of emulsification in the most practical manner in numerous industrial sectors such as in food and dairy.