bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effectiveness of Genital Hygiene Education Given to Secondary School Girls
Authors: Gökşin İlknur , Demirhan İlknur
Published: May 2024

Objective: The study was conducted to examine the effect of genital hygiene education given to adolescent female students on the genital hygiene behaviors of adolescents.
Method: This one-group pre-test post-test quasi-experimental model study was conducted between May 9 - June 7, 2022, with 103 female students who could communicate verbally and who voluntarily agreed to participate in the study. Genital hygiene training was given to the students. Data were collected using a personal information form and genital hygiene behavior scale (GHBS).
Results: The percentage of students who were in the age group of 15-16 years was 64.1%, 75.3% were in the 10th grade, 69.9% had mothers who had completed primary/secondary education, and 50.5% had menarche at the age of 12-13 years. General hygiene, menstrual hygiene, awareness of abnormal findings sub-dimensions and total GHBS scores were found to be statistically significantly higher in the post-test than in the pre-test (p<0.05).
Conclusion: As a result of the study, it was determined that students had incorrect, inadequate practices regarding genital hygiene, and the education provided increased the correct hygiene behaviors. In line with these results training should be planned to raise awareness on reproductive health, general hygiene, genital and menstrual hygiene, especially in institutions such as schools, hostels and dormitories where adolescent girls are together collectively.
Kahramanmaraş Merkezli Depremler Sonrası Samsun İline Göç Eden Depremzedelerin Sağlık İhtiyaçlarının Değerlendirilmesi
Authors: Kalaycı Gizem Jülide , Şimşek Yurt Nur
Published: May 2024

Amaç: Çalışmamızda Kahramanmaraş merkezli depremler sonrası Samsun iline göç eden depremzedelerin, afetin hemen ardından belirlenen sağlık ihtiyaçlarının değerlendirilmesi amaçlanmıştır.
Yöntem: Araştırmamız Samsun İlkadım İlçe Sağlık Müdürlüğü mobil ekipleri tarafından 10.02.2023 ile 27.02.2023 tarihleri arasında Samsun ili İlkadım ilçesine gelen depremzedelerle yapılan yüz yüze görüşmeler sonucunda toplanan kayıtlara dayalı verilerin incelenmesi ile gerçekleştirilmiş tanımlayıcı bir çalışmadır. Bireylere, Samsun İl Sağlık Müdürlüğü tarafından oluşturulan; kişilerin sosyo-demografik bilgileri, kronik hastalıkları, ilaç kullanımları, engellilik ve gebelik gibi sağlık durumları ile depremin hemen ardından gelişen sağlık ihtiyaçlarının sorgulandığı form yüz yüze uygulanmıştır.
Bulgular: Toplam 948 kişi ile yüz yüze değerlendirilme gerçekleştirilmiş olup, 412’si (%43,4) kadındı. Ortalama yaş 30,11±20,79’du (min:0-maks:87). Depremzedelerin büyük bir kısmı (%83,4) ev ortamında konaklıyordu. 145 kişi (%15,3) devlete bağlı kurumlarda, 12 kişi (%1,3) otellerde kalmaktaydı. 246 kişinin (%26,0) kronik hastalığı vardı. %3,1 oranında (n=30) engellilik durumu belirlendi. Sağlık ihtiyaçları incelenen kişilerin 26’sının fiziksel yaralanma yaşadığı, 1 kişinin metalle yaralanma nedeniyle tetanoz aşı talebinin olduğu belirtildi. 312 kişi (%32,9) psikolojik desteğe ihtiyaç duyuyordu. Deprem öncesinde 126 kişi (%13,3) gözlük kullanıyordu. 51 kişi (%5,4) gözlüğünü kaybettiğini, gözlük talebi olduğunu bildirdi. 7 kişinin (%0,7) gebelik durumu mevcutken, 3 kişi bu durum ile ilgili muayene talep etti.
Sonuç: Depremzedelerin sağlık açısından primer ihtiyaçlarının ortaya konulması, ileride yaşanması muhtemel afetler açısından öngörü niteliğindedir. Bu durumun dikkate alınmasının, hizmet sunumunda ve alınması gereken tedbirlerde büyük önem taşıdığı düşünülmektedir.
Time Series AI Model for Acute Kidney Injury Detection Based on a Multicenter Distributed Research Network: Development and Verification Study
Authors: Heo Suncheol , Kang Eun-Ae , Yu Jae Yong , Kim Hae Reong , Lee Suehyun , Kim Kwangsoo , Hwangbo Yul , Park Rae Woong , Shin Hyunah , Ryu Kyeongmin , Kim Chungsoo , Jung Hyojung , Chegal Yebin , Lee Jae-Hyun , Park Yu Rang
Published: May 2024

Background

Acute kidney injury (AKI) is a marker of clinical deterioration and renal toxicity. While there are many studies offering prediction models for the early detection of AKI, those predicting AKI occurrence using distributed research network (DRN)–based time series data are rare.

Objective

In this study, we aimed to detect the early occurrence of AKI by applying an interpretable long short-term memory (LSTM)–based model to hospital electronic health record (EHR)–based time series data in patients who took nephrotoxic drugs using a DRN.

Methods

We conducted a multi-institutional retrospective cohort study of data from 6 hospitals using a DRN. For each institution, a patient-based data set was constructed using 5 drugs for AKI, and an interpretable multivariable LSTM (IMV-LSTM) model was used for training. This study used propensity score matching to mitigate differences in demographics and clinical characteristics. Additionally, the temporal attention values of the AKI prediction model’s contribution variables were demonstrated for each institution and drug, with differences in highly important feature distributions between the case and control data confirmed using 1-way ANOVA.

Results

This study analyzed 8643 and 31,012 patients with and without AKI, respectively, across 6 hospitals. When analyzing the distribution of AKI onset, vancomycin showed an earlier onset (median 12, IQR 5-25 days), and acyclovir was the slowest compared to the other drugs (median 23, IQR 10-41 days). Our temporal deep learning model for AKI prediction performed well for most drugs. Acyclovir had the highest average area under the receiver operating characteristic curve score per drug (0.94), followed by acetaminophen (0.93), vancomycin (0.92), naproxen (0.90), and celecoxib (0.89). Based on the temporal attention values of the variables in the AKI prediction model, verified lymphocytes and calcvancomycin ium had the highest attention, whereas lymphocytes, albumin, and hemoglobin tended to decrease over time, and urine pH and prothrombin time tended to increase.

Conclusions

Early surveillance of AKI outbreaks can be achieved by applying an IMV-LSTM based on time series data through an EHR-based DRN. This approach can help identify risk factors and enable early detection of adverse drug reactions when prescribing drugs that cause renal toxicity before AKI occurs.
Geospatial Imprecision With Constraints for Precision Public Health: Algorithm Development and Validation
Authors: Harris Daniel , Delcher Chris
Published: May 2024

Background

Location and environmental social determinants of health are increasingly important factors in both an individual’s health and the monitoring of community-level public health issues.

Objective

We aimed to measure the extent to which location obfuscation techniques, designed to protect an individual’s privacy, can unintentionally shift geographical coordinates into neighborhoods with significantly different socioeconomic demographics, which limits the precision of findings for public health stakeholders.

Methods

Point obfuscation techniques intentionally blur geographic coordinates to conceal the original location. The pinwheel obfuscation method is an existing technique in which a point is moved along a pinwheel-like path given a randomly chosen angle and a maximum radius; we evaluate the impact of this technique using 2 data sets by comparing the demographics of the original point and the resulting shifted point by cross-referencing data from the United States Census Bureau.

Results

Using poverty measures showed that points from regions of low poverty may be shifted to regions of high poverty; similarly, points in regions with high poverty may be shifted into regions of low poverty. We varied the maximum allowable obfuscation radius; the mean difference in poverty rate before and after obfuscation ranged from 6.5% to 11.7%. Additionally, obfuscation inadvertently caused false hot spots for deaths by suicide in Cook County, Illinois.

Conclusions

Privacy concerns require patient locations to be imprecise to protect against risk of identification; precision public health requires accuracy. We propose a modified obfuscation technique that is constrained to generate a new point within a specified census-designated region to preserve both privacy and analytical accuracy by avoiding demographic shifts.
Assessing Hypotension Incidence and Dosing Strategies of Sacubitril/Valsartan in Real-World Heart Failure Management: Protocol for A Retrospective, Multicenter, Cohort Study (Preprint)
Authors: Jadhav Uday M , Mohanty Arun , Shah Jay , Chenniappan M , Krishna K. Naveen , Sattur Ameet G. , Mukhopadhyay Mainak
Published: May 2024

BACKGROUND

The burden of heart failure (HF) and hypertension in India underscores the need for effective management strategies. Sacubitril/valsartan, an angiotensin receptor neprilysin inhibitor (ARNi), has emerged as a pivotal therapy for HF with reduced ejection fraction (HFrEF). However, concerns about hypotension often hinder optimal dosing in clinical practice. The objective of this study is to observe the incidence of hypotension in HFrEF patients and to evaluate the best clinical practice to achieve an optimal tolerated dose of sacubitril/valsartan without treatment discontinuation.

OBJECTIVE

The primary aim of this study is to evaluate the incidence of hypotension among HFrEF patients receiving sacubitril/valsartan and assess the feasibility of dose titration to achieve optimal tolerated doses in real-world settings. Secondary objectives include evaluating treatment outcomes, tolerability, and factors influencing dosing adjustments.

METHODS

This is the protocol of a retrospective, multicenter cohort study aimed at assessing real-world usage patterns of sacubitril/valsartan among Indian HFrEF patients, focusing on hypotension occurrence and optimal dose attainment. Patients aged 18-80 years diagnosed with HFrEF (left ventricular ejection fraction (LVEF) ≤ 40%) and initiated on sacubitril/valsartan between November 2023 and May 2024 will be included. Baseline and follow-up data, including demographics, medical history, and treatment outcomes, will be analyzed using appropriate statistical tests. Data from approximately 150 healthcare facilities will be collected using a structured Case Report Form (CRF).

RESULTS

The study was initiated in February 2024. As of manuscript submission, 892 individuals have been recruited, with data collection expected to conclude by the end of May and results anticipated by June.

CONCLUSIONS

This study aims to contribute valuable insights into optimizing sacubitril/valsartan therapy for HFrEF patients in India, addressing concerns about hypotension and dosage optimization. The study seeks to inform clinical practice and enhance patient care by elucidating real-world usage patterns and outcomes

CLINICALTRIAL

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The Direction of Ethnic Vocational Education under the Way of “Positional Education”
Authors: Wang Heyan
Published: May 2024

The essence of education is to develop people and develop humanity. No matter what kind of education, must follow this essential provisions. Vocational education for ethnic minorities is an important link in the education chain and plays an important role in improving the quality of ethnic minority members and adapting to economic and social needs. However, the emergence of common assimilation and marketization in the objectives and courses of ethnic vocational education has brought about the lack of ethnic and professional characte ristics in ethnic vocational education, which has caused the problems such as the failure of the trained talents to meet the needs of local economic and social development. The concept of “positional education” has brought a new Angle of thinking about this issue to ethnic vocational education. Ethnic vocational education must first be accurately positioned, and then it can seek development.
Globalización desde un enfoque de derechos
Authors: Compte Nunes Guillem , Lomelí Vanegas Leonardo , Sánchez Vargas Armando , Ramírez Hernández Nashieli , Concha Malo Miguel , Cadena Roa Jorge , López Leyva Miguel Armando , Belausteguigoitia Marisa , Zavala Hernández Ruth
Published: May 2024

Dos grandes fenómenos sociales a escala planetaria convergen a partir de la segunda mitad del siglo pasado, la globalización y los derechos humanos. El primero determina no solo las formas de relación financiera, comercial y comunicacional, sino también la comprensión del mundo como totalidad, como comunidad humana que debe abordar problemas sin fronteras. El segundo da pautas para orientar las decisiones políticas y las políticas públicas que deben guiar la convivencia global en el presente siglo. Los derechos humanos configuran una primera moral universal (producto de un diálogo histórico entre naciones: nuestro derecho de gentes contemporáneo) que busca dignidad y bienestar para cada persona y pueblo. De la mano de la Cátedra Extraordinaria “Francisco de Vitoria-Bartolomé de las Casas” de la Coordinación de Humanidades, UNAM, este volumen reúne contribuciones sobre temas de coyuntura, en México y en el mundo, que relacionan ambos fenómenos. En estas páginas ilustres estudiosas y estudiosos discuten la economía, los derechos humanos, la democracia, el derecho y el género, el cambio climático, y la religión en clave globalización desde un enfoque de derechos.
La Constitución de Apatzingán. 22 de octubre de 1814
Authors: Romero Flores Jesús
Published: May 2024

La Colección Bicentenario de la Constitución de Apatzingán incluye una narración de los hechos históricos que condujeron a la Independencia de México en letra de Jesús Romero Flores.
Review of Oral Tablet
Authors: Dupade Amol Balasaheb , Hirave Pramod Shivaji , Dadas Vikas Bapurao
Published: May 2024

Abstract: Oral drug delivery is noninvasive, has a high rate of patient compliance, is easy to handle, and doesn't require any special sterile settings, it is the most popular method of administration. Nevertheless, a number of physical, biological, and pharmacological obstacles that certain medications must overcome in order to be absorbed into the systemic circulation reduce their therapeutic efficiency. The use of nanocarriers to deliver drugs orally has proven to be an effective solution to the aforementioned problems and is being explored as a potential replacement for oral medication administration. This chapter provides an overview of the latest developments in the use of nanocarriers for oral medication delivery in the treatment of different disorders. The chapter also describes how diverse nanocarrier designs and technologies improve therapeutic potential by overcoming physical, biological, and biochemical obstacles. it is easy to produce, has few sterility limitations, is less expensive, has flexible dosage form design, and has high patient compliance, oral drug delivery (ODD) is the most convenient and favored method of drug administration. However, low medication bioavailability—which is influenced by three crucial factors—is one of the difficulties associated with oral drug delivery. The other is solubility. Many mathematical models that predict the medication's rate of solubility and dissolution have been developed in order to achieve efficient drug absorption in vivo. Similarly, models that are noncellular and cellular determine permeability. Furthermore, the medication's behavior in the gastrointestinal tract (GIT) is influenced by physiological parameters, such as pH, microbial colonization, and enzymes, as well as intrinsic drug properties. A drug's dosage form is a method of getting it into a living organism. The medicine must be administered to the site of action at a rate and concentration that will maximize therapeutic benefit and minimize side effects in order to provide the intended result. Although the oral method is still commonly used, swallowing tablets and capsules can be a regular problem. As a result, numerous studies on cutting-edge drug delivery methods have been conducted. This review focuses on oral dispersible tablets, a novel approach to drug delivery systems that are currently more focused on formulation and set a new course that not only helped patients increase their level of therapy compliance.
Real Time Snap Attendence
Authors: Gavaskar Aarya , Adsul Atharva , Sayyed Ahmad Ali , Atram Prassana , Kadu Prof. Anil
Published: May 2024

Abstract: Traditional attendance methods, such as manual roll calls and sign-in sheets, are often time-consuming, prone to errors, and ineffective in preventing proxy attendance. Face recognition technology offers a promising solution to these challenges by providing an accurate and efficient way to mark attendance. This paper presents Snap Attendance, a facial recognition-based attendance management system that utilizes deep learning algorithms to identify and verify student identities. Snap Attendance streamlines the attendance process, reduces administrative burden, and enhances attendance accuracy.
Enhancing Online Furniture Shopping for Seniors and Physically Challenged Individuals through AR
Authors: Kumar Anil , S Spoorthi H , S Tejas S , V Chirag K , M Sagar Gowda K
Published: May 2024

Abstract: “Augmented reality (AR) technology has potential to revolutionize the way we interact with and visualize the world around us. One area where this technology has great potential is in the field of furniture design and home decor. The goal of the Augmented Reality Furniture project is to develop a platform which allows users to virtually preview and interact with furniture in their own home environments using AR technology. Using a smartphone or other AR-enabled device, users will be able to see how different furniture pieces will look and fit in their own living spaces before making a purchase. The project will involve the use of 3D models of a variety of furniture items, aswell as the development of AR software that can accurately place and scale these models in the user's environment. The platform will also include a user-friendly interface for browsing and selecting different furniture items, as well as tools for customizing and arranging the items in the virtual space.
Streamlining Dental Clinic Operations Introducing the Web Application for Efficient Dental Clinic Management
Authors: Karunamurthy Dr. A. , Udhayakumar V. , Roshini S.
Published: May 2024

Abstract: The Dental Clinic Management System web application is a comprehensive software program designed to automate and optimize the various tasks and operations that occur in a dental clinic. Historically, dental clinics have kept their records manually and done their paperwork on paper, which has led to many errors, inefficiencies, and delays.To tackle these problems, the Web Application for Dental Clinic Management System provides dental professionals and personnel with an easy-to-use interface that makes daily operations more efficient. The DCMS web application assists patients in scheduling a dentist appointment at a dental clinic. The system simplifies the administration of patient data, encompassing personal data, medical history, and treatment documentation. Precise diagnosis and treatment planning are ensured by the easily accessible and updated information by authorized staff. Only the patient that have been registered in Dental Clinic Management System be able to use the system. It is run by highly qualified and experienced health professionals.This website covers Admin panel, Dentist panel and Patient panel. User can perform search by dentist specialty, gender, and dentist name. User can browse through dentist profile and view their specialty information. The register user can choose and book an appointment at the flexible time and date. Dentist can view the patient appointment and they can confirm or cancel their reservation. Admin can able control and maintain Dentist and patient information through a computerized process. And Admin can view and replay the unregistered users queries, also view the medical report of the patient.
NGO Automation Suite with RPA
Authors: Nikam Riya , Rai Hrithik
Published: May 2024

Abstract: The COVID-19 outbreak has forced every NGO to operate with reduced manpower and facing lot of operational challenges. Every NGO is trying to automate end to end process of campaign outreach, Donation management, Report generation, KYC Verification and Customer email query automation. This virtual registration experience will help NGO to collect, manage and update registration details easily for multiple campaigns. User will receive automated email with KYC verification, Hospital Appointment and Certificate of Appreciation.
A Fast Browsing System with Colour Image Enhancement for Surveillance Videos
Authors: Kamble Prof. Kirti K. , Deshmukh Prof. Rahul G. , Shinde Prof. Bhavana
Published: May 2024

Abstrac: Surveillance cameras have been widely installed in large cities to monitor and record human activities for different applications. Since surveillance cameras often record all events 24 hours/day, it necessarily takes huge workforce watching surveillance videos to search for specific targets,thus a system that helps the user quickly look for targets of interest is highly demanded. This paper proposes a quick surveillance video browsing system with colour image enhancement. The basic idea is to collect all of moving objects which carry the most significant information in surveillance videos to construct a corresponding compact video. The compact video rearranges the spatiotemporal coordinates of moving objects to enhance the compression, but the temporal relationships among moving objects are still kept. Thecompact video can preserve the essential activities involved in the original surveillance video. This paper presents the details of browsing system and the approach to producing the compact video from a source surveillance video. At the end we will get the compact video with high resolution.
Structural and Economical Analysis of Cable-Stayed Bridges
Authors: Banerjee Animikh , Polley Devnita
Published: May 2024

Abstract: Cable-stayed bridges have emerged as prominent structures in modern civil engineering, renowned for their aesthetic appeal, structural efficiency, and economic viability. This review paper provides a comprehensive analysis of the structural and economic aspects of cable-stayed bridges. It encompasses a thorough examination of various design considerations, construction techniques, material selection, and economic factors influencing the feasibility and performance of cable-stayed bridges. Through the synthesis of existing literature and case studies, this paper aims to offer insights into the key factors driving the design, construction, and economic evaluation of cable-stayed bridges, thereby aiding engineers, planners, and decision-makers in making informed choices in bridge infrastructure development projects.
Extract Text from Video
Authors: Wadaskar Ghanshyam , Udrake Sanghdip , Bopanwar Vipin , Upganlawar Shravani , Getkar Prof. Minakshi
Published: May 2024

Abstract: The code import the YoutubeTranscriptionApi from youtube_transcription_api libray, The YouTube video ID is defined. The transcription data for the given video ID is fetched using get_transcription method. The transcription text is extracted from the data and stroed in the transcription variable. The transcriptipn is split into lines and thenjoined back into a single string. Finally the processed transcript is writen into a text file name “Love.text” with UTF-8 encoding. The commented-out code block is an alternative way to write the transcript into a text file using the open function directly. which you can use if you prefer.
Document Management System Generative AI and AWS Comprehend
Authors: Tiwari Niharika , Srivastava Prashansa , Rana Dr. Sadhana
Published: May 2024

Abstract: Document Management Systems that have Generative AI and cloud features integrated in them can help users to save time. The generative ai features can boost creativity, quality and cloud resources can greatly help expand the scope of the system. A document management system built entirely on the cloud offers mobility and freedom of expression and analysis. With analysis features, users can derive important insights from texts in place and cloud storage offers the mobility to access these features from anywhere. From this, comes the possibility of an application that allows users to choose their features depending upon their needs. It is a deeper stride into the pay-as-you-go-model where the users pay only for what they use. The application provides a model to what a truly dynamic feature rich application might look like
La ánima en pena de Luis Ambrosio Morante: una muestra de dramaturgia gótica con fines independentistas.
Authors: Landini María Belén
Published: May 2024

La ánima en pena es una comedia que Luis Ambrosio Morante decide firmar bajo seudónimo. La trama se centra en el regreso de un Coronel a quien se había dado por muerto en la guerra. Los muertos que se levantan de su tumba y las manifestaciones el más allá constituyen el eje gótico de esta pieza, que se asoma al incipiente romanticismo rioplatense. Por otro lado, no deja de estar presente en este manuscrito la ideología independentista del dramaturgo, encarnada en el soldado abnegado y dedicado a la defensa del territorio local.
El Benjamin e Imamura
Authors: Lama Bárrbara
Published: May 2024

El presente trabajo quiere problematizar los textos de Walter Benjamin Experiencia y pobreza y El Narrador desde sus consecuencias en la concepción de barbarie. Para ello se propone el arte como lugar de levantamiento de una paradoja: el autorretrato en tanto manifestación artística que busca reafirmar la experiencia arte/vida y, en la obra de Shōhei Imamura para la película 11 ́09 ́ ́01 September 11,en que ésta exhibe su anomalía en la imposibilidad de narración de toda experiencia.
La historia del quiz show en televisión
Authors: Toledo Aral Sergio , Fernández Estrella
Published: May 2024

Los quiz shows conforman gran parte de las parrillas de programación en todos los países desde los inicios de la televisión. Su influencia en el entretenimiento es patente y continua siendo un pilar para mantener los índices de audiencias de las principales cadenas.
El concurso de preguntas y respuestas se fundamenta en una fórmula clásica pero ha ido evolucionando a través de sus formatos internacionales más icónicos. En la investigación se realiza una aproximación a los antecedentes y la evolución de los concursos que transitan entre lo erudito y lo popular, entre el conocimiento académico y el conocimiento rutinario.
- sin editorial - la muerte del texto.
Authors: Venegas Romero Pablo
Published: May 2024

...
me parece súper interesante la puesta en escena del texto en la actualidad, de las palabras como tal, que tienden a perder el rigor, pero más interesante me parece el hecho de que volvamos a comunicarnos con un formato que en su fisonomía se presta para interpretaciones diversas, frente a la precisión con la que una palabra se permite expresar, pues quiere decir que hemos culturizado imaginariamente nuestra comprensión, y abierto el espectro para que sin ser directos ni finos, nos encontramos en aquellos lugares comunes que nos pertenecen a todos, sin excepción.
In Traditional Greenhouses A field Research in Terms of Occupational Health and Safety (Antalya Example)
Authors: ÇOŞGUN Ahmet , ÇANAKÇI Murad
Published: May 2024

Although different levels of mechanization or automation systems are used in greenhouse cultivation depending on the infrastructure characteristics, there is an intensive use of human labor, especially for cultural operations. Therefore, the importance of occupational health and safety issues in greenhouse cultivation is increasing. Mechanization tools used, air conditioning systems, chemicals used, labour-intensive processes that require a certain muscle power and a certain posture during work, working at height, indoor air characteristics are among the main issues that need attention in terms of occupational health and safety. When the issues related to occupational health and safety in Turkey are examined, it is seen that studies have been carried out on different subjects such as working with agricultural machinery, chemical use, etc. However, it can be said that the studies on greenhouse cultivation are limited compared to other production branches. It is seen that the studies conducted consist of studies aimed at determining the situation in the form of field studies. Again, when the studies were examined, no study on indoor air in greenhouses, which is a closed environment, was found.
In this study, it is aimed to examine the indoor air in terms of occupational health and safety in traditional greenhouses belonging to family businesses. In the study, the data were collected from 135 farmers in traditional greenhouses during the year and a questionnaire study was conducted in terms of occupational health and safety.
Vibrating Mesh Performance During Low Flow Oxygen Therapy in Neonates
Authors: Burke Rachel , Eain Marc Mac Giolla , Joyce Mary , Fernández Elena Fernández , Loughlin Ronan Mac
Published: May 2024

Background & Objectives: Supplemental oxygen and aerosol therapy
may be used in combination as a treatment for neonates suffering from
hypoxemia caused by respiratory diseases. Due to cost and lack of
availability of oxygen cylinders in some countries, oxygen concentrators
are a reported substitute. This study was designed to determine whether
using an oxygen concentrator and low-flow oxygen therapy impacts aerosol
drug delivery in a simulated spontaneously breathing neonate patient.
Methods: A vibrating mesh nebuliser (VMN; Aerogen Solo) was used
to aerosolise a 500µL dose of salbutamol. The aerosol was delivered via
a nasal cannula to a neonate head model in combination with oxygen
concentrator at gas flow rates of 0.2, 1.0 and 5.0 LPM and low-flow
oxygen therapy at gas flow rates of 1.0, 4.0 and 5.0 LPM. The mass of
drug in terms of emitted and tracheal doses were recorded. The impact of
VMN operation and refill on circuit pressure in both systems was also
measured. Results: The oxygen concentrator delivered a higher
emitted dose than the low flow system, the largest emitted dose (%)
being 20.58 ± 0.50% and 14.69 ± 0.89% respectively at 1.0 LPM , p =
0.018. The largest tracheal dose (%) was generated with the oxygen
concentrator, 11.01 ± 0.29% at 5.0LPM compared to 9.66 ± 1.53% for
low-flow oxygen therapy, p = 0.073. Refill and operation of the VMN did
not impact the circuit pressure in either system. Conclusions:
This study shows that the system used to provide combinational aerosol
and supplemental oxygen therapy has a significant impact on the quantity
of nebulised therapeutic delivered to the patient.
Growth-defense trade-offs promote habitat isolation between recently-diverged species
Authors: Harencar Julia , Salazar-Amoretti Diego , Garcia-Robledo Carlos , Kay Kathleen
Published: May 2024

Trade-offs are crucial for species divergence and reproductive
isolation. Trade-offs between investment in growth versus defense
against herbivores are implicated in tropical forest diversity.
Empirically exploring the role of growth-defense trade-offs in closely
related species’ reproductive isolation can clarify the eco-evolutionary
dynamics through which growth-defense trade-offs contribute to
diversity. Costus villosissimus and C. allenii are recently diverged,
interfertile, and partially sympatric neotropical understory plant
species primarily isolated by divergent habitat adaptation. This
divergent adaptation involves differences in growth rate, which may
constrain investment in defense. Here, we investigate growth-defense
trade-offs and how they relate to the divergent habitat adaptation that
isolates these species. We characterize leaf toughness and chemistry,
evaluate the feeding preferences of primary beetle herbivores in
controlled trials and field-based experiments, and investigate natural
herbivory patterns. We find clear trade-offs between growth and defense:
slower-growing C. allenii has tougher leaves and higher defensive
chemical concentrations than faster-growing C. villosissimus. Costus
villosissimus has rapid growth-based drought avoidance, enabling growth
in drier habitats with few specialist herbivores. Therefore,
growth-defense trade-offs mediate synergistic biotic and abiotic
selection, causing the divergent habitat adaptation that prevents most
interspecific mating between C. villosissimus and C. allenii. Our
findings advance understanding of ecological speciation by highlighting
the interplay of biotic and abiotic selection that dictates the outcome
of trade-offs.
Cancer and One Health: tumor-bearing individuals can act as super spreaders of symbionts in communities
Authors: Tissot Sophie , Meliani Jordan , Chee Matthew , Nedelcu Aurora , Boutry Justine , Tökölyi Jácint , Hamede Rodrigo , Roche Benjamin , Ujvari Beata , Thomas Frédéric , Dujon Antoine
Published: May 2024

Recent theoretical advances in the One Health approach propose that
greater attention should be paid to cancer pathologies due to their
potential to render hosts more susceptible to infectious agents,
potentially transforming them into super-spreaders within ecosystems.
However, this hypothesis lacks experimental validation. Using a
community of Hydra species and a commensal ciliate species (Kerona
pediculus) that colonizes them, we tested whether tumoral polyps of H.
oligactis, compared to healthy ones, played an amplifying role in
ciliate load, potentially resulting in higher likelihood of infection
for other community members through spillovers. Results revealed a
higher proliferation rate of ciliates on tumoral polyps compared to
healthy ones, leading to infection of other hydras, albeit with varying
spillover magnitudes among recipient species. This study is the first
proof of concept that tumoral individuals within communities could act
as super-spreaders of symbionts within and between species, influencing
biotic interactions and dynamics in ecosystems.
The Sensitivity Analysis Using Adjoint Method In Numerical Modeling of Electric Potential Distribution of the Transmission Lines
Authors: Paganotti Andre , Saldanha Rodney , Lisboa Adriano Chaves , Afonso Márcio Matias , DUANE B. A. M.
Published: May 2024

This paper proposes a new methodology for sensitivity analysis
evaluation, fast and with high precision of the electric potential
distribution near the transmission lines (TL’s). The TL is modeled by
the finite element method and the sensitivity of the cable positions is
obtained using the adjoint method. The sensitivity of the objective
function during the optimization process by using methods based on
gradient information is obtained by using the adjoint method. The exact
sensitivity obtained by the adjoint method concerning the numeric model
of the TL’s results in new geometries of the bundles conductors with
high surge impedance loading. These geometries are not possible to get
using analytic models. The sensitivities of a large number of conductors
by phase are obtained with high precision and very low computational
cost using adjoint sensitivities, which are independent of the number of
design variables. The central finite difference (CFD) method is used to
calculate the sensitivities and to validate the adjoint method. With
this methodology, the FEM model of the TL can be used during the
optimization process without compromising the required computational
processing time.
Az intraduktális prosztatakarcinóma diagnózisa és klinikopatológiai jelentőségének bemutatása prosztata-tűbiopsziás mintában egy ritka eset kapcsán
Authors: Farkas Tamás , Szabó Balász , Tordé Ákos , Tóth Zoltán , Salamon Ferenc
Published: May 2024

Bevezetés: Az intraduktális prosztatakarcinóma (IDC-P) egy ritkán előforduló szövettani entitás, amelynek jellemzője a prosztatikus daganatos sejtek duktuszokon/acinuszokon belüli terjedése. Az IDC-P hisztomorfológiai kategóriája klinikopatológiai szempontból két különálló elváltozást jelenthet: az invazív karcinómával asszociált IDC-P-t, valamint a ritkábban előforduló izolált IDC-P-t, amely a prosztata adenokarcinóma prekurzorának tartható. Szövettani differenciáldiagnózisa komoly kihívást jelent, az atípusos kribriform léziók közül az egyik legfontosabb a magas grádusú prosztata intraepithelialis neopláziától (HGPIN) való elkülönítése. Az intraduktális prosztatakarcinóma jelenléte rendszerint magas Gleason-értékű invazív karcinómával, nagy tumortömeggel, és hátrányos prognosztikus paraméterekkel társul. Esetismertetés: Esetünkben páciensünk prosztata-tűbiopsziás mintájának szövettani vizsgálata során izolált intraduktális prosztatakarcinómát észleltünk. Az eredmény ismeretében rebiopszia végzése mellett döntöttünk. Következtetések: A prosztata atípusos kribriform elváltozásainak megfelelő szövettani differenciáldiagnosztikája fokozott klinikai jelentőséggel társul, tekintettel arra, hogy a különböző entitások eltérő terápiás és prognosztikus következményekkel járnak. Mindazonáltal nincs egyértelmű konszenzus, hogy a prosztata-tűbiopsziás mintában jelenlévő izolált IDC-P rebiopsziát, vagy azonnali radikális kezelést igényel-e. Mivel azonban az izolált IDC-P csak extrém raritásként fordult elő a vizsgálatokban, és az invazív prosztatakarcinómával való társulás valószínűsége meglehetősen nagy, abban egyetértés mutatkozik a szerzők között, hogy az intraduktális karcinóma egyedüli megjelenése a tűbiopsziás mintában minimálisan igen szoros obszervációt igényel. A jövőbeli nagyobb prospektív vizsgálatok sokkal pontosabb képet nyújthatnak az IDC-P incidenciájáról, és segíthetnek meghatározni az IDC-P biopsziás mintában való jelenlétének független prediktív értékét, ezáltal segítséget nyújthatnak ezen betegek kezelésében, a klinikai döntéshozatal irányításában.
Violence Today: A Comparative Reading of Jacques Ellul and René Girard
Authors: Lysenko Julien
Published: May 2024

This article explores the differences and intellectual affinities between Jacques Ellul and René Girard on the question of violence in today’s world. In this respect, both thinkers share the conviction that violence has changed form because of material and spiritual factors. The presentation of these factors will enable us to show the differences, but above all the complementarities, between Girard and Ellul. Finally, based on these two authors, the article sketches out an attempt to describe the future of violence.
Unveiling the Link: Anemia as a Risk Factor for Cerebrovascular Accidents
Authors: Obeagu* Emmanuel Ifeanyi
Published: May 2024

Anemia, a prevalent hematological condition characterized by decreased red blood cell count or hemoglobin levels, has emerged as a significant risk factor for cerebrovascular accidents (CVAs) and commonly known as strokes. This review explores the intricate connection between anemia and the occurrence of CVAs, elucidating the underlying mechanisms and clinical implications. Anemia contributes to stroke risk through multiple pathways, including impaired oxygen delivery to the brain, alterations in cerebral hemodynamics, and disruption of neurovascular homeostasis. Furthermore, iron deficiency anemia’s predominant etiology-not only exacerbates hypoxia but also compromises neuronal integrity, predisposing individuals to ischemic and hemorrhagic stroke events. The hemodynamic consequences of anemia, including cerebral hypo-perfusion and increased thromboembolic risk, underscore its role as a silent culprit in stroke pathogenesis. Anemia-induced alterations in blood viscosity, endothelial dysfunction, and compensatory vasodilation contribute to the vulnerability of cerebral vasculature to ischemic insults. Moreover, iron deficiency exacerbates neurocognitive impairment and promotes neuro degeneration, exacerbating the risk of vascular cognitive decline and hemorrhagic stroke. Routine screening for anemia, particularly in highrisk populations, coupled with targeted interventions aimed at correcting underlying etiologies and optimizing hemoglobin levels, is essential for mitigating stroke risk and improving clinical outcomes.
University professors’ representations on an online EMI course in Paraná - Brazil
Authors: Passoni Taisa , Calvo Luciana Cabrini Simões , El Kadri Michele Salles , Stillwell Christopher
Published: May 2024

In Brazilian higher education institutions, English as a Medium of Instruction (EMI) courses and workshops play a key role in helping professors to rethink their methodology and their concepts of language, especially regarding English conceived as a lingua franca. In an attempt to bring a local perspective for EMI, this paper examines university professors’ representations on an online EMI course for professors from nine public universities in Paraná. It is grounded on the concept of representation from critical discourse analysis. The results reveal the beliefs and motivations of the participants concerning EMI in Brazil.
DISKURSUS PEREMPUAN DALAM MEDIA SOSIAL INSTAGRAM: STUDI DESKRIPTIF CYBERBULLYING DI AKUN @LAMBE_TURAH
Authors: Marsya Ulmi
Published: May 2024

Artikel ini akan mendiskusikan bagaimana perkembangan teknologi ternyata menjadi ancaman tersendiri bagi kaum perempuan. Sosial media, disatu sisi merupakan salah satu wadah komunikasi paling populer dikalangan masyarakat terutama anak muda untuk dapat mengaktualisasikan dirinya, namun disisi lain ia menjadi boomerang tersendiri bagi para penggunanya ketika kita tidak dapat mengendalikan arus komunikasi yang sangat kompleks dalam sosial media karena jangkauannya yang sangat luat serta sifat komunikannya yang memungkinkan untuk dapat menyembunyikan identitasnya. Perkembangan teknologi komunkasi ternyata tidak dibarengi dengan semakin meningkatnya kualitas etika dalam masyarakat. Misalnya dengan semakin menjamurnya bullying dalam sosial media. Ungkapan kebencian menjadi hal yang sangat lumrah terjadi dalam sosial media. Dalam hal ini, bully dan ungkapan kebencian yang terjadi, ternyata bias gender. Perilaku bully terhadap perempuan sering kali dipengaruhi oleh diskursus-diskursus yang biasa dilekatkan pada perempuan misalnya hal-hal yang berbau objektifikasi seksual. Pembahasan ini akan menggunakan data kualitatif yang disajikan dalam bentuk analisis deskriptif terhadap femonema cyberbullying di media sosial instagram khususnya yang terjadi pada kaum perempuan.
Perilaku Konsumen dalam Keputusan Pembelian Sepatu AZA 6 Edisi Hari Merdeka
Authors: Nurfatimah Erisha , Saputra Windhi Tia , Wahyuningratna Ratu Nadya
Published: May 2024

Fenomena merek sepatu Ardiles yang berkolaborasi dengan DBL Indonesia menghasilkan produk sepatu AZA 6 edisi Hari Merdeka yang diluncurkan tanggal 12 Agustus 2019 dan berhasil terjual habis hanya dalam empat hari setelah tanggal perilisannya menjadi hal yang menarik untuk diteliti. Karena melihat pasar sepatu Indonesia di tahun 2018 khususnya sepatu olaraga, brand sepatu internasional masih unggul jauh Nike memimpin dengan 30%, sementara Ardiles berada di urutan kelima dengan 3,7%. Namun ditengah gempuran brand asing, Ardiles berhasil menarik banyak konsumen untuk melakukan pembelian produk baru mereka. Dengan menggunakan pendekatan kualitatif deskriptif penelitian ini akan melakukan analisis pada perilaku konsumen dalam pengambilan keputusan pembelian Sepatu AZA 6 edisi Hari Merdeka. Teknik pengumpulan data yang digunakan berupa wawancara mendalam dengan informan yang berasal dari konsumen sepatu AZA 6 edisi Hari Merdeka langsung, observasi dan dokumentasi. Hasil penelitian menunjukan dalam melakukan keputusan pembelian, perilaku konsumen dipengaruhi oleh berbagai faktor yang dapat memberikan konsumen kepuasan, seperti keterbatasan produk yang menjadikannya eksklusif, keunikan konsep dan desain produk, kualitas produk, hingga harga yang ditawarkan.
Analysis of operation of heat exchangers of hot water supply system in the scheme of reliable and safe heat supply of residential buildings
Authors: Samarin O. D.
Published: May 2024

The scheme of internal heat supply of residential buildings with independent connection of the heating system to the external heating networks and connection of the heater of the DHW system in a parallel single-stage arrangement, providing reliability of heat supply and the necessary comfort in the premises due to the unrelated regulation of heat supply for heating, ventilation and DHW even in case of fluctuations in water intake, is considered. A mathematical model describing the non-stationary modes of operation of DHW system heaters under the conditions of implementation of this scheme is constructed and investigated. Calculations were carried out using this model, including numerical simulation on a computer using the Monte Carlo method. It is established that in this case, a decrease in the average heat transfer coefficient of the heater of the DHW system due to fluctuations in the flow of mains water following the daily change in water consumption at the DHW can be neglected, since this decrease lies within the usual error of engineering calculation, despite the fact that this coefficient depends on the flow in a nonlinear way, and its growth during the period of increased water intake for DHW does not fully compensate for the decrease during the reduction of water consumption. At the same time, it is proved that with a characteristic number of heat transfer units in a DHW system heater referred to the heated stream, the total amount of heat transferred can decrease quite noticeably, by an amount of 10 to 12 percent; however, with a rational choice of the heater size, such a decrease is within the limits allowed by the applied factors of margin when setting determination of the heat exchange surface.
The Megalith-Builders of Lebanon
Authors: Wygnańska Zuzanna , Steimer-Herbet Tara
Published: May 2024

Discoveries by Polish and Swiss archaeologists in the Middle East are bringing us closer to the culture of the first megalith-builders from 5,000 years ago.
The ITO thin films deposited by magnetron sputtering for solar cell applications
Authors: Szindler Marek , Szindler Magdalena M. , Lukaszkowicz Krzysztof , Matus Krzysztof , Nosidlak Natalia , Jaglarz Janusz , Fijalkowski Mateusz , Nuckowski Paweł
Published: May 2024

The paper presents the results of research on the surface topography and electrical properties of ITO thin films deposited by PVD for applications in silicon photovoltaic cells. The surface condition and chemical composition were characterized using a scanning electron microscope and the thickness and optical constants were measured using a spectroscopic ellipsometer. To compare the impact of the preparation process on the properties of layers, deposition was carried out with three different temperatures: 25, 200 and 400°C. As the temperature increased, the surface roughness changed, which correlated with the results of structural tests. The crystallite size increased from 11 to 46 nm. This, in turn, reduced the surface resistance. The electrical properties were measured using a four-point probe method and then the prepared solar cells containing ITO thin films in their structure were examined. By controlling the deposition parameters, the surface resistance of the deposited layer (26 Ohm/ ) and the efficiency of the prepared solar cells (18.91%) were optimized. Currently, ITO has the best properties for use in optoelectronics and photovoltaics in among the known TCO layers. The magnetron sputtering method is widely used in many industries. Therefore, the authors predict that TCO layers can replace currently used antireflection layers and reduce the number and dimensions of front metal contacts in solar cells.