bluuebunny/crossref_metadata_2025 huggingface dataset:
The use of Human Intestine to Deliver Recombinant Proteins Which Macroorganism Needs
Authors:   President of Microbial Biocatalyst International, Inc. and Inorgcarbdiesel, Inc, United States, Tyurin Michael Vladislavovich
Published: October 2022

The Author has performed the partial body fat removal in the volunteer who has tendency to increase the body weight. The Author investigated the problem of food fat digestion on rabbits and successfully used it for the design and use of the proprietary fat removal column. The observations of the fat transport in the rabbit blood had brought the Author to understanding that the intestine is a wide and open gate for the recombinant proteins, if inhabit the intestine with the genetically engineered members of the normal human intestinal; microflora. It is paramount to do the genetic engineering of the component of the human normal intestinal microflora for about 200 hours, not longer, as otherwise long cultivated in vitro the engineered microorganisms do not adhere to the intestinal cells of the host thus making the whole procedure the waste of the very well paid time (patient/ health insurance pays). The Author has designed the procedure to cure the Diabetes II and anemia in another volunteer. The success determined the need for the look in the future, when the overcrowded Earth population might start relocating to other planets: vaccines for the relocating people.
Professional Development for Rural Stem Teachers on Data Science and Cybersecurity: A University and School District Partnership
Authors:   Texas Tech University, Maina Faith , Smit Julie , Serwadda Abdul
Published: October 2022

The professional development (PD) was a six-week long summer-intensive NSF- funded project that took place at a large university in western Texas. It was designed to provide a research-rich learning environment in data science and cybersecurity for STEM teachers in the region, which is mainly rural. Because of geographical isolation, rural teachers lack the resources to prepare their 6th -12th grade students for STEM careers and often find it difficult to bring innovative science teaching into their schools. The team was comprised of nine teachers, five professors, and six graduate students. In analyzing teacher reflections, we found the teachers gradually developing a scientist persona. They acquired sophisticated pedagogical knowledge to integrate complex concepts into their 6th-12th STEM curriculum without sacrificing the state standards, while creating a community of learners. This led to reduced feelings of isolation often experienced by rural teachers. It is clear that partnerships between universities and rural school districts can transform the way STEM disciplines are delivered, creating a strong pipeline for rural students in the STEM workforce.
Research Reflections on the Positives of COVID-19 for Work in the Northern Territory
Authors:   Batchelor Institute of Indigenous Tertiary Education, Guenther John
Published: October 2022

Across Australia, COVID-19 has certainly disrupted our lives. For many researchers it has caused us to push the pause button on our activities and rejig our timelines, our methods and our ethics approvals to suit the changed conditions. As an educational researcher in the Northern Territory, my plans between March and July 2020 were thrown out the window as not only our borders were closed but our access to remote communities was suspended with additional â€˜biosecurity restrictionsâ€™ which were designed to protect people living away from major centres, and who had limited access to health services. Not only were there limitations on travel, but many of the sites of my work, such as schools, were closed. Conferences were cancelled, virtual meetings became the norm and â€˜the officeâ€™ shifted from the university to home. But it wasnâ€™t all bad, and in this short article I want to focus on the benefits of a year of COVID-19 and how I think my workâ€”and the work of other researchersâ€”will have changed forever as a result. These are personal reflections and I acknowledge that othersâ€™ experience of research in a COVID-19 environment may well be different.
Disruption, Diversity, and Dynamic Developments in Rural Education During COVID-19
Authors:   University of Newcastle, Ledger Susan , Fuqua Melyssa ,   University of Melbourne
Published: October 2022

Major disruptions occurred in 2020 that impacted all aspects of our lives. For many, challenges and opportunities surrounding education were central with many sectors and individuals globally responding in diverse and dynamic ways. The variety of disruptions â€“ from fires, floods, and the ongoing COVID-19 pandemic â€“ resulted in unprecedented educational solidarity. Globally and across nations, jurisdictions learned from each other and provided support collectively. The international collection of papers within this issue brings examples from Canada, USA, China, and Australia that address several of these points.
Challenging Rural Stereotypes
Authors:   Batchelor Institute of Indigenous Tertiary Education, Guenther John , Ledger Susan ,   University of Newcastle
Published: October 2022

Rural and remote students, schools and teachers are placed in stereotypical ‘boxes’ in ways that suggest they have problems that need fixing. The language that surrounds these problems are metrocentric biased and perpetuate persistent negative discourse (Ledger, Masinire, Delgado & Burgess, 2021). For example remote First Nations students in Australia are often described as ‘disadvantaged’, ‘behind’ with ‘poor’ academic outcomes (Roberts & Guenther, 2021). Rural schools face ‘obstacles to success’ (O'Keefe, Olney, & Angus, 2012) that city schools do not. Staffing is often described as an ‘issue’ to be fixed: “Australia’s rural schools are still staffed with younger, inexperienced teachers, who do not appear to stay long” (White, 2016, p. 41). And parents are sometimes blamed for a lack of engagement with their children’s schooling (Lea, Wegner, McRae-Williams, Chenhall, & Holmes, 2011). While the metrics of the metropolis might support these views, the measures that determine the problematics of rural and remote education tend to place a veil over the ontological reality of what it means to be a teacher, student or parent engaged with issues of schooling for rural and remote students.
The Influence of Parenting Styles on Child-Parent Relationship Among Chinese and Bumiputera in Sabah
Authors: Qinghua Liu , Ompok Connie Shin @ Connie Cassy
Published: October 2022

Several studies on child-parent relationships in Malaysia have been conducted before COVID-19. After the pandemic, most child-parent relationship studies were conducted abroad, such as Singapore, Greece, Belgium, and the United States. However, there are no published studies that investigated the child-parent relationship among Chinese and Bumiputera parents with preschool children in Sabah. This study aims to examine the difference in parenting styles between Chinese and Bumiputera parents with preschool children in Sabah. As well, to examine the influence of parenting styles on child-parent relationships. In the pilot study, 49 parents of preschool-aged children were surveyed. The reliability and validity are tested and convinced. This study would like to provides parents, educators, and the government with a preliminary picture of parenting styles and child-parent relationships to develop a strategy to improve or adjust early childhood education in the post-pandemic.
Assessment of the influence of the composition of atmospheric microparticles on redox homeostasis of alveolar macrophages
Authors: Barskova Lyudmila S. , Vitkina Tatyana I. , Veremchuk Ludmila V. , Gvozdenko Tatyana A.
Published: October 2022

Introduction. The components and dimensions of suspended particulate matter (SPM) depend on territory, the sources of generation. The aim is to assess the relationship between the quality and dispersed composition of atmospheric SPMs with oxidative and antioxidant processes in alveolar macrophages. Materials and methods. The impact of actual multi component pollution of the surface layer of atmospheric air on alveolar macrophages (AMs) of Wistar rats was modelled. Correlations between the characteristics of AMs and pollution were assessed using the Spearman correlation coefficient. Results. The predominant contribution of the quality characteristics of SPM has been founded. The effect of the dispersed composition increases with an increase of the finely dispersed particles fraction. Metal particles have caused oxidative damage to lipids, with the formation of stable lipid products. The antioxidant system (AOS) has been characterized by the activation of compensatory response. Mineral components have caused irreversible oxidative damage to lipid and protein compounds, activating the thioredoxin formation. Soot particles have showed the most pathogenic effect, leading to oxidative damage to lipids, proteins, and nucleic acids. The AOS stress was accompanied by an increase in the formation of oxidized glutathione and thioredoxin, which performs restoration of proteins and DNA. Limitations. Our study characterizes the response of the AMs of a particular territory. Conclusion. The established tendencies characterize the impact of composition of SPMs of the urban atmospheric on AMs. The study made it possible to identify the most sensitive criteria for the response of AMs upon contact with atmospheric SPMs (thioredoxin, protein carbonyl, 8-hydroxy-2’-deoxyguanosine).
Assessment of the content of heavy metals and polycyclic aromatic hydrocarbons in the soil of the city of Svirsk, Irkutsk region
Authors: Merinov Alexey V. , Alekseenko Anton N. , Shayakhmetov Salim F. , Zhurba Olga M.
Published: October 2022

Introduction. One of the environmental problems is the contamination of soil cover with toxicants. The soil performs the functions of a biological absorber, destroyer and neutralizer of various contaminants, it has the most important role in the life of society. The aim of the study is to assess the quantitative content of mobile forms of heavy metals and polycyclic aromatic hydrocarbons in the soil in the urbanized territory of the Irkutsk region on the example of the city of Svirsk. Materials and methods. Content of heavy metals and polycyclic aromatic hydrocarbons (PAHs) in the soil of Svirsk, selected in various parts of the city (multi-storey buildings, private sector, industrial zone, forest park zone) and in the background point outside the city was studied. The determination of heavy metals was carried out by atomic absorption spectrometry, PAH - by gas chromatography-mass spectrometry. Results. The levels of metals in the soil samples varied within 2.9-366.7 mg/kg for lead; 0.82-3.1 mg/kg for copper; 0.2-36.0 mg/kg for zinc; 3.5-67.9 mg/kg for iron; 65.5-149.7 mg/kg for manganese; 0.12-4.8 mg/kg for chromium and 0.04-0.28 mg/kg for cadmium. The content of benzo(a)pyrene and the amount of PAHs ranged from 1.1 to 387.3 and from 61 to 4600 µg/kg, respectively. Limitations. The limitations of the study are related to the need for further study of the content of these pollutants in biological media Conclusion. Maximum allowable values were found to be exceeded in 90.9% of samples for lead (maximum excesses were 52.4-61.1 MPC), in 72.7% of samples for benzo(a)pyrene (maximum excesses were 9.1-19.4 MPC), as well as single excesses for copper (1.03 MPC) and zinc (1.3 and 1.6 MPC).
Pandemic COVID-19 and environmental pollution (literature review)
Authors: Sizova Elena N. , Shmakova Ludmila N. , Vidyakina Evgenia V.
Published: October 2022

The purpose of this article is to review and analyze the literature on the impact of the COVID-19 pandemic on the environment and, conversely, on the environmental impact on the spread of SARS-CoV-2. The literature search was carried out using the MedLine, PubMed and eLIBRARY databases. Thanks to measures to combat the COVID-19 pandemic, the world experienced a sharp decline in economic activity, which in turn led to improvements in air and water quality and contributed to the global reduction in greenhouse gas emissions, but this improvement was short-lived. Quarantine measures not only protect the population from COVID-19, but also positively affect the environmental quality. At the same time, the amount of plastic medical waste, such as used public and personal protective equipment against COVID-19, increased, and as a result, the problem of their disposal arose. This has led to the contamination of the water and land physical spaces and created the population contamination threat. Using the concentration of SARS-CoV-2 RNA from urban wastewater and subsequent counting of viral RNAs by quantitative reverse transcriptase polymerase chain reaction, an early determination of COVID-19 was carried out by modelling in specific populations. The presence of SARS-CoV-2 RNA in wastewater is a potential public health risk. High levels of environmental pollution (long-term exposure to derivatives of fossil fuel combustion), meteorological parameters (ionizing and UV radiation), and cigarette smoke, are considered to be additional factors increasing the spread and mortality of COVID-19. The SARS-CoV-2 viability depends on aquatic and terrestrial environmental parameters.
The role of microcirculation in the conducting structures of the nervous system in patients with vibration disease burdened by metabolic syndrome
Authors: Rusanova Dina V. , Kuks Anna N. , Lakhman Oleg L. , Slivnitsyna Natalya V.
Published: October 2022

Introduction. The study of microcirculation processes in peripheral nerve damage remains a necessary area of experimental and clinical research, because the microvascular bed is one of the most important systems in which the disease manifests itself in the early stages. The aim of the study is to identify the role of microcirculation disorders in the state of central and peripheral conductive structures in patients with vibration disease (VD) associated with combined exposure to general and local vibration, and burdened with metabolic syndrome (MS) and diabetes mellitus (DM). Materials and methods. Group 1 included patients with VD associated with combined exposure to general and local vibration, group 2 - persons diagnosed with VD, burdened with MS, group 3 - with a diagnosis of VD, burdened with DM. At the 1st stage of the study, basal blood flow was studied, at the 2 nd stage - load functional tests (respiratory and occlusive). The state of sensory and motor axons of the nervous system was determined. Results. In patients of the examined groups, there was proved a relationship between the indicators of the state of peripheral nerves and central structures with the indicators of microcirculation, the state of the myogenic level of regulation, with the index of specific oxygen consumption and the index of relative perfusion oxygen saturation in the microcirculation. In patients with VD, burdened with MS and DM, an association was found between changes in axons with an indicator of the intensity of functioning of the regulatory systems of the microvascular bed, indicators of the levels of active regulation of microcirculation (myogenic, neurogenic and endothelial) and indicators characterizing the dynamic state of the microcirculation system. Limitations. The disadvantage of the study is the fact that the parameters of the microcirculation system determined in the peripheral departments were extrapolated to the central structures, and were not determined in the capillary network of the brain. Conclusion. Changes in the microcirculatory bed were established to be a link in the pathogenesis of demyelination processes in VB associated with the combined effects of general and local vibration, and vibration disease burdened with MS and DM.
Risk factors for the development of comorbid diseases of occupational bronchopulmonary pathology
Authors: Beigel Elena A. , Katamanova Elena V. , Efimova Nataliya V.
Published: October 2022

Introduction. Comorbid diseases in patients with occupational bronchopulmonary pathology determines the severity of the underlying disease. The purpose was to identify risk factors for the development of concomitant diseases in occupational bronchopulmonary pathology in aluminum production workers. Materials and methods. One hundred thirty men with an occupational pathology including chronic obstructive pulmonary disease (COPD), bronchial asthma (BA), chronic non-obstructive bronchitis (CNB) and their combination were examined. Inclusion criteria - male gender, age from 43 years to 72 years, established diagnosis of an occupational disease of the lower respiratory tract. The assessment of the significance of risk factors was carried out using the Bayesian method. Risk factors were taken: the patient’s occupation: total work experience, work experience in aluminum production, age, smoking. The odds ratio for the development of comorbid pathology (OR (CI)) was calculated. Results. Concomitant pathology was detected in 97% of patients. The informativity of risk factors is presented as a series: occupation < age < total experience < experience in aluminum production < smoking. The OR of two comorbid diseases is higher in COPD patients (OR=10.8) and COPD+BA (OR=15.0). The risk of one comorbid disease is higher in CNB patients. Limitations. The results cannot be generalized to workers as the group included only men. Conclusion. The risk of two or more comorbid diseases is typical for patients with COPD or a combination of COPD+BA; electrolysis workers and persons working in various workshops; with more than 25 years of experience; currently continuing to smoke.
Risk of low back pain among Indonesian volcano sulfur miners: a retrospective cohort study
Authors: Akbar Kurnia Ardiansyah
Published: October 2022

Introduction. Kawah Ijen is the main volcano sulfur-producing in Indonesia. There is still a lot of conventional Sulfur mining going on there. Every day, Sulfur miners work walking about 8.5 km to transport Sulfur weighing 70-100 kilograms using simple transporters that are only held on one shoulder to the Sulfur collection site. The health problem that is the focus of this study is the incidence of low back pain (LBP) in volcano sulfur miners. Aims and objectives. This study aims to determine the magnitude of the risk of low back pain in sulfur miners to prevent occupational diseases.. Materials and methods. This research was carried out for three months. This study adopted a retrospective cohort study design. The research sample amounted to 140 respondents taken by simple random sampling. The data collection technique was carried out by interview and lasegue test and Patrick’s test to see the respondents’ positive or negative of low back pain. Data analysis was carried out using rank spearmen test. Results. The results showed a relationship between the incidence of low back pain in the community and work (p-value < 0.000). Indonesian volcano sulfur miners are 5,032 times more at risk of low back pain than other public workers. Conclusion. Volcano Sulfur Miners are more at risk of experiencing low back pain than other occupations.
Application of the Intensity Normalization Indicators method for predicting occupational morbidity in leading industries
Authors: Kuleshova Marina V. , Pankov Vladimir A. , Dyakovich Marina P.
Published: October 2022

Introduction. Identification of risk factors for the occurrence of occupational diseases by comparing various prognostic criteria is one of the most important tasks of hygiene and occupational health. The purpose of the study is to develop a prognostic matrix of occupational morbidity (OM) in the leading industries of the Irkutsk region for a set of main predictor factors using the method of intensity normalization indicators (INI). Materials and methods. There was used an information array of long-term OM in the leading industries of the Irkutsk region. The method of calculating weight indices was used to assess the strength of the influence of OM predictor factors and the INI method was used to calculate the prognostic significance of the factors. Results. The risk of occupational disease (OD) has been established to be associated with belonging to a certain occupation (OR=61.8), combined exposure to harmful factors in the working environment (OR=23.8), due to the imperfection of the technological process and equipment. The work experience with a harmful occupational factor, the age of employee, the industry are also significant, but the degree of their influence on the occurrence of OD is much lower. Based on the predictor factors, the risk of OD was calculated, its possible range (0.019-0.412 conventional units) with three subranges (favourable, uncertain and unfavourable prognosis) was determined. The risks of OD in persons with a work experience of 1-4 years, under the age of 40, exposed to the combined effects of physical factors, working as excavator driver and an assembler-riveter, were 0.269 and 0.226 (uncertain forecast). The risk values of OD in workers of these occupations increase by 24.4% and 29.1%, respectively, with an increase in length of service and age, reaching a maximum at the age of 50-59 years with an work experience of 30 or more years (0.334 and 0.292, unfavourable prognosis). The limitations of this INI model include the non-inclusion of clinical, functional, biochemical and socio-psychological indicators of workers among the predictor factors. Limitations. An analysis of one thousand eight hundred sixty two cases of newly diagnosed occupational diseases over a 10-year period, 11 main predictor factors, which is a sufficient reference sample, was made to study occupational morbidity in the leading industries of the Irkutsk region and developing a prognostic matrix. Conclusion. The use of INI makes it possible to give an integrated risk assessment of the OD both for individual factors and for their complex, and to determine risk groups.
Workplace stress: the main causes and preventive measures (literature review)
Authors: Fagamova Alina Z. , Kaptsov Valery A. , Karimova Liliya K. , Shapoval Inna V. , Muldasheva Nadezhda A.
Published: October 2022

Today stress is one of the most common pathological conditions. Associated with the stress, it’s level, anxiety, depression, and burnout syndrome are still increasing and lead to the spread of psychological maladaptation and borderline states. Working population is under continuous exposure not only to social, but also occupational stress, which creates a financial burden for institutions and whole society. This review outlines the main directions of studying the impact of work-related stress on the workers’ body and examines the main occupations affected by stress and prevention as well. Literature search was carried out among databases including Scopus, Web of Science, MedLine, CyberLeninka, RSCI. The workers of dangerous occupations (transport drivers, locomotive crews, law enforcement, firefighters, rescuers), managers, working migrants, and healthcare workers are most susceptible to occupational stress. The number of people suffering from bad habits increases due to work-related stress as well. Workers use nicotine, alcohol, caffeine, sleeping pills and narcotic drugs as a negative way to overcome stress and its consequences. A special focus has been put on the influence of occupational stress on diseases development due to hazardous working conditions and features of work process management such as shift work and “emotional labour”. Furthermore, there are presented main directions of preventive measures to reduce the level of industrial stress.
Comparative nutritional characteristics in schoolchildren with different nutritional status
Authors: Bogdanova Olga G. , Efimova Natalia V. , Mylnikova Inna V.
Published: October 2022

Aim. To assess the state of actual nutrition of children of early and middle school age with different nutritional status in the industrial center of Eastern Siberia. Materials and methods. The study included five hundred forty children, such as 145 7-10 years children in group I, 395 11-14 years children in group II. The criteria for dividing into subgroups were based on calculating the Z-scores of the body mass index by age. Analysis of the obtained results was performed using generally accepted statistical methods. Results. Analysis of the study results indicated a suboptimal ratio of nutrient critical for population health, protein, carbohydrate, polyunsaturated fatty acids (PUFA), omega-3 (ω-3), fat surplus, saturated fatty acids and added sugar. Dietary patterns of boys with high BMI had large values of the proportion of saturated fatty acids to total calories, which exceeded optimal physiological norms in group I by 52.22% and in group II by 37.68%. Girls of group I with a high BMI had a greater value of the proportion of added sugar to the calorie content of the food diet - 74.63%. Limitations of the study. Dietary information was obtained through questionnaires, all information was obtained from a one-moment examination. Conclusion. Some of the factors associated with impaired nutriome formation in the study children were imbalance in dietary patterns and surplus added sugars, which demonstrates the need to improve nutrition strategies at the regional level based on current meta-analyses.
The analysis of students' attitude to healthy lifestyle and reproductive health care
Authors: Kretova Irina G. , Belyaeva Olga V. , Vedyasova Olga A. , Pavlenko Snezhanna I.
Published: October 2022

Introduction. In connection with low competency of young people in the issue of life safety it is relevant to analyze entirely the students` attitude to healthy lifestyle. Also it is important to assess the students` knowledge about reproductive health and ways of keeping it well. Materials and methods. The authors undertook questionnaire method and asked anonymously seven hundred sixty three students of Samara National Research University. Survey consists of 38 questions regarding students` age, leisure time, academic performance and influence of the process of education on health, family social status, attitude to sport, psychoactive substances. Also students were asked about their knowledge of healthy lifestyle components, sexually transmitted infections, possibility of prevention and contraception. Results. The authors found out that young men do sports more often than girls. Also boys use more often cold training and eat regularly. Every tenth girl has a lack sleep, sleep duration is less than 5-6 hours. 30% of boys and girls drink alcohol two or three times a month, 35% of students smoke. 12.45% of young people (men and women) experimented with drugs. Peculiarities of students`sexual behaviour are early beginning of sexual intercourse and frequent changing of sexual partners. The authors revealed low level of students` knowledge about contraception, sexually transmitted infections and its sequela, preventive measures. Limitations. Only students of Samara National Research University were involved into this investigation except students of Biology Faculty (because they are more informed in the field of healthy life style and reproductive health) and students who do sports professionally or who have chronic diseases. Conclusion. The problem of reproductive health care and primary prevention of sexually transmitted infections can`t be solved only by medical staff. Correction of risky behaviour is an interdisciplinary challenge that demands comprehensive approach focused on group and social norm changing. Universities must play an important role in this issue making it possible for professors to have classes of academic discipline such as «Family health», « Fundamentals of Medicine» where qualified professors with higher medical education can discuss with students the issue of reproductive behavior.
Assessment of the risk associated with chemical pollution of air environment of sports facilities for children’s health
Authors: Mylnikova Inna V. , Efimova Natalia V. , Kudaev Andrey N.
Published: October 2022

Introduction. Acute and chronic exposure to chemicals is accompanied by a complex of disorders in the activity of the respiratory, immune and other systems. Purpose is to assess the health risk to children from short-term exposure to pollutants in air of out- and indoor sports facilities. Materials and methods. The air quality of ice arenas, sports halls for martial arts and sports halls in schools was studied using maximum samples; out-door air - according to the average monthly and maximum concentrations registered in 2017-2021. The risks of acute exposure for indoor and outdoor sports facilities are calculated. Results. Against the background of a single excess of the maximum one-time (in gyms) and average monthly (in the atmosphere) concentrations of chemicals, risks to the health of children involved in sports were identified. The maximum share contribution to hazard index (HI) for the respiratory system in the air of the ice arena is made by formaldehyde (58.3%), in school halls - by suspended solids (47.3%). The seasonal dynamics of pollution is revealed, which confirms the importance of thermal power emissions. The maximum Hazard Quotient (HQ) PM10 = 3.1-3.9 is established in winter, and in summer it is 3-4 times lower. The content of PM2.5 in the air is responsible for the extremely high risk in May (HQ = 12.5). The limitation of the results is due to the lack of indoor studies and insufficient knowledge on the impact of acute health effects. Limitations the results are due to the small number of indoor studies and insufficient knowledge about the impact of acute health outcomes. Conclusion. Further study of the short-term effects of indoor and outdoor air pollution from sports facilities is needed.
The assessment of the antihypoxic properties of the complex compound of oxymethyluracil with acetylcysteine in the model of histotoxic hypoxia
Authors: Repina Elvira F. , Bakirov Ahat B. , Gimadieva Alfiya R. , Karimov Denis O. , Kudoyarov Eldar R. , Timasheva Gulnara V. , Khusnutdinova Nadezhda Yu. , Baygildin Samat S. , Smolyankin Denis A. , Mukhammadiyeva Guzel F.
Published: October 2022

Introduction. Oxymethyluracil is an effective antihypoxant in a model of histotoxic hypoxia. Acetylcysteine combines the properties of a toxicotropic nonspecific and toxicokinetic antidote, promotes the synthesis of glutathione in the body. The aim of the research was a preliminary assessment of the antihypoxic properties of the complex compound of oxymethyluracil with acetylcysteine in the model of histotoxic hypoxia. Materials and methods. To study the antihypoxic properties, a model of acute histotoxic hypoxia was used. The studied compound was injected into the abdominal cavity of experimental mice three times with an interval of 30 minutes at 100 and 500 mg/kg of body weight, then after 30 minutes the toxicant was introduced. Comparators were oxymethyluracil and acetylcysteine. Results. The complex compound of oxymethyluracil with acetylcysteine in the model of acute histotoxic hypoxia statistically significantly was established to increase the lifespan of mice at a dose of 500 mg/kg of body weight. A dose of 100 mg/kg of the compound is practically ineffective. Limitations. The limitations of the study are related with antihypoxic properties of the new complex compound of oxymethyluracil with acetylcysteine previously studied in one model of hypoxia (histotoxic), because oxymethyluracil (as an antihypoxant) is most effective in this experimental model. For a final judgment on the antihypoxic properties of the studied compound, it is necessary to continue studies on other models of hypoxia. In addition, in order to identify possible synergism (potentiation) of the action of oxymethyluracil and acetylcysteine, it seems appropriate to conduct studies to evaluate the antihypoxic effect with their simultaneous administration (in the form of a simple mixture). Conclusion. A new complex compound of oxymethyluracil with acetylcysteine can be recommended for further wider (preclinical) research as a potential antihypoxant.
Assessment of air pollution based on the analysis of long-term observations in the city of Bratsk
Authors: Efimova Natalia V. , Rukavishnikov Viktor S.
Published: October 2022

Introduction. The problem of monitoring air quality and health risk remains important. The aim is to study the long-term dynamics of air pollution in Bratsk in order to improve the monitoring system and prevent impact on the population. Materials and methods. The dynamics of emissions and the integral indicator of air pollution “P” in Bratsk for 1984-2018 was studied. Results. Emissions decreased by 2 times in 1984-2018, the minimum level was observed in 1995-2005. The trend in “P” is associated with the emissions (rxy = 0.76, p = 0.000). The concentrations of 3,4benz (a) pyrene, carbon disulfide made main contribution to the “P” value. An increase in the content of 3,4-benz(a)pyrene has been recorded since 2015. The city population is at risk for respiratory, immune, bone, and central nervous system disorders; the formation of systemic pathology and additional deaths. Limitations. Gross emissions were estimated according to statistical reports with certain errors, monitoring programs for the concentrations of chemicals recorded at various observation posts and changed in different years. Conclusion. In Bratsk, several districts can be distinguished, differing in the level of pollution by 2-3 times, due to meteorological conditions for dispersion and urban planning features. The presented experience can be useful in the implementation and evaluation of the effectiveness of the national project “Ecology”.
A crowdsensing cloud-based microservice for weather forecast
Authors: Selis Dimitris , Papaioannou Evi , Moisiadis Giorgos , Kaklamanis Christos
Published: October 2022

We present a cloud-based microservice enabling individual users to have access to local air pressure measurements and a proof-of-concept web application providing shot-term weather forecasts based only on local crowdsensed data. Our microservice has been developed using state-of-the-art web technologies and cutting-edge technologies related to cloud computing. Apart from its individual interest and potential usefulness, our microservice and proof-of-concept web application show how modern cloud-based technologies and tools can be nicely combined to improve the community daily routine and wellbeing.
INFLUENCE OF PRODUCT INNOVATION ON THE PERFORMANCE OF COFFEE COOPERATIVES IN KENYA
Authors: Kuguru Peter , Jaensson Jan-Erik , Nganga Kinyanjui
Published: October 2022

Purpose: The purpose of the study was to assess the influence of product innovation on the performance of coffee cooperatives in Kenya.

Methodology: A descriptive research design was applied. The target population of this study was 525 coffee cooperative societies in Kenya registered with the Commissioner for Cooperatives and licensed by AFFA (Coffee Directorate) as at 30th of October 2016. The sample size was 227 respondents. Structured questionnaires were used to collect primary data from the selected respondents.

Findings: The results of the study revealed that product innovation and performance are positively and significantly related (β=0.631, p=0.002). This indicated that developments of new products are essential for the improvement of the coffee cooperatives’ performance.

Unique Contribution to Theory, Policy and Practice: The study recommended adoption of technology for the development of new services, new functions, and formation of new alliances. The study further recommended an organization to employ and develop a high technology for its product in order to determine strategic position to adopt the differentiation position or the cost leadership position. This study is recommended as it will benefit scholars and researchers who will gain insight on the influence of product innovation on performance of coffee co-operatives hence use it as a source of reference for other researches. The results of this study will contribute new knowledge which will provide the government and other stakeholders with better ways of managing co-operatives and improving their production.
Comprehensive Study of Human Behaviour in Relation to Social Context
Authors: Laiu Bianca
Published: October 2022

In this article, the concept of groups is dissected in further detail. The notion of groups is quite broad and may be applied not just to individuals but also to a variety of other living things outside humans. People are more likely to establish groups when they have comparable experiences or ways of thinking about how to satisfy their requirements. The purpose of this article is to acquaint the reader with the idea of groups and to explain how one can form a general description of groups by first comprehending the formation process, the formation of groups, the characteristics and types of groups, and other topics related to acquainting oneself with and understanding formal groups as well as the behavior of individuals within those groups. The reader will become familiar with the idea of groups and will learn how one can form a general description of groups.
Телекоммуникация хизматлари кўрсатиш шартномаларини тузиш асослари ва тартиби
Authors: Xursanov Rustam
Published: October 2022

Телекоммуникация хизматлари кўрсатиш шартномалари тузишда муайян талаблар ва шартларга риоя этиш ҳамда шартнома предмети, тарафларнинг ҳуқуқи ва мажбуриятларини аниқ ифодалаш лозим бўлади. Шу билан бирга, телекоммуникация хизматларини кўрсатиш шартномасининг намунавий ва стандарт шартлар асосида тузилиши, тузилиш тартибига кўра оммавий ва қўшилиш шартномаси ҳамда абонент шартномаси сифатида баҳоланиши масалалари ҳам илмий ва амалий нуқтаи назардан долзарбдир. Чунки мазкур шартнома ҳали фуқаролик ҳуқуқи фани нуқтаи назаридан янги шартнома бўлиб, ҳуқуқни қўллаш амалиёти нуқтаи назаридан ҳам бу шартнома ҳозирча тўлиқ намоён бўлган эмас. Шу сабабли телекоммуникация хизматларини кўрсатиш шартномасини тузишда тарафларга қўйиладиган талаблар, оператор ва провайдернинг мажбуриятлари, абонентнинг ҳуқуқлари ва унга нисбатан бериладиган имтиёзлар масалалари тадқиқ этилиши лозим.
Мусиқа дарсларида ўқувчиларнинг билим ва малакаларини мустаҳкамлаш
Authors: Азизов Ориф
Published: October 2022

Мусиқа маданий хаётимизда кенг ўрин тутган, инсон шахсиятини ривожлантиришда муҳим аҳамият касб этадиган санъат туридир. Мусиқа тарбияси, нафосат тарбиясининг асосий ва мураккаб қирраларидан бири бўлиб, атрофдаги гўзал нарсаларни тўғри идрок этишга ва қадрлашга ўургатади. Мусиқа инсонни юксак дид билан қуроллантиради ва маънавий дунёқарашини шакллантиради. Мусиқа инсон ҳиссиётига кучли таъсир кўрсатиш имкониятига эга бўлиб, ўқувчиларни нафосат оламига олиб кириш ва ғоявий-ахлоқий тарбиялашнинг муҳим воситасидир.
TRAINING FOR CHILDREN’S MOTOR DEVELOPMENT AT TPA AL-MUBASYIR DESA DIBAL, KECAMATAN NGEMPLAK, KABUPATEN BOYOLALI, CENTRAL JAVA.
Authors: Wibowo Yudi , Nugraha Alma Fikri Setya , Lestari Indah Ayu Puji , Widyastuti Suryaningtyas , Muslimin Toriqot Armada
Published: October 2022

Abstract : Practicing motor skills is important for children, given that childhood is a golden period in child development. One technique in training children's motor skills is to provide guidance or physical exercises that are in accordance with the portion of children's physical abilities. This activity aims to improve motor skills in children through viewing animation movie, coloring pictures, and leisurely strolling for children. The activities carried out showed the attitudes and behavior of children at TPA (Taman Pendidikan Al-Quran) Al-Mubasyir to be better than before, children became more creative, thorough, responsive to the surrounding environment, and enthusiastic in participating in learning.
Keywords: motor, training, children
JOURNALISTIC CARICATURE TRAINING to FASILITATE YOUTH CREATIVITY
Authors: Kartinawati Erwin , Swasono Bening Tri
Published: October 2022

This community service activity was carried out to provide training to students on journalistic caricatures. The training was intended for senior high school level students considering that their age was youth or adolescent. Teenagers usually had a lot of creative ideas that need to be explored and expressed positively. They had feelings and or opinions about the conditions that occur. All was to be appreciated better so their activity couldn't damage and pollute the surrounding environment, such as painting the walls of public facilities. Social media feeds also need to be posted with more exciting and brilliant uploads when giving specific reactions to social, political, or economic phenomena. With this journalistic caricature training and competition, students were also expected to know about (mass) media content production. In this way, students as members of society were passive public who consume media content and learn how mass media content was produced/presented to the public.
Iron and cast iron in the architecture of Bucharest. Late 19th Century
Authors:   “Ion Mincu” University of Architecture and Urbanism, Bucharest, Mortu Anamaria
Published: October 2022

Changes in the architecture of the city after the second half of the 19th century will fully benefit from the large scale adoption of iron and cast iron as constructions materials. These materials are used as a technical solution against the spread of fi re or to reinforce buildings, at the same time allowing the transition from a “closed”, massive architecture to a “framed” one, a landmark of the great Western cities brought to this area by foreign architects working during this time. Cast iron pillars and laminated profi le beams (sometimes even rail tracks) will gradually replace massive masonry and allow the opening of interior spaces to the “light” of the streets. In the context of the disappearance of a major part of the built heritage, researching the archives may provide an objective insight of the print left by the two materials on architecture and the city.
Archaeological report on the exhumation of the Greek Catholic Bishop Vasile Aftenie (1899-1950), Bellu Catholic Cemetry, Bucharest
Authors:   The Vasile Pârvan Institute of Archaeology, Bucharest, Dragoman Radu-Alexandru , Oanță-Marghitu Sorin ,   National Museum of Romanian History, Bucharest, Palincaș Nona ,   The Vasile Pârvan Institute of Archaeology, Bucharest
Published: October 2022

This article presents the results of an archaeological intervention carried out in 2010 involving the exhumation of the remains of Bishop Vasile Aftenie (1899-1950). The intervention took place as part of the efforts of the Greek Catholic Church of Romania to beatify said bishop, who, from a Christian perspective, died a martyr’s death: he was arrested in 1948 by the Securitate (the Romanian secret police under communism), tortured and pressured into renouncing his faith. The inventory items discovered (fragments of clothing, a collar), the stature of the deceased as computed using anthropological analysis (and in keeping with witness statements), as well as circumstancial evidence confirms the oral testimony relating to the site of the bishop’s burial. Among the material used to fill the grave we found many coins as well as a glass phial with a metal lid containing some strands of hair and a slip of paper containing a prayer for the lifting of curses. The coins and phial, together with the candles from the grave, represent the material expression of the homage and prayers offered up by the faithful to the bishop. The results of our archaeological research rendered material expression to the relationship existing between the bishop’s remains and the faithful, confirming the fact that, long before the Romanian Greek Catholic Church began considering the bishop for beatification, some people had already begun honouring him as a saint of their own accord.
Fragments d’architecture avec images sculptées à Tomis: les Dioscures et Héraclès
Authors:   Institute d'Archéologie « Vasile Pârvan », Bucarest, Mărgineanu-Cârstoiu Monica
Published: October 2022

L’auteur observe sur les quatre tronçons de fûts de colonnes ornés d’images sculptées des Dioscures et d’Héraclès découverts à Tomis l’influence de l’architecture orientale pamphylienne. La présence singulière des types de colonnes décorées d’images sculptées est connue jusqu’à présent uniquement à Pergé et permet de formuler une hypothèse sur la filiation directe du type de colonne sculptée de Tomis et l’idée architecturale-symbolique des colonnes de Pergé. Par conséquent on suppose que parmi les marbriers qui ont travaillé pendant le II-IIIème siècle ap. J.-C. á Tomis se trouvaient aussi des pamphyliens. L’image des Dioscures a également été remarquée sur un fragment de linteau évidé et reproduite sur un pilastre en placage taillés en marbre. Sont proposées quelques variantes sur la possibilité d’identifier les ensembles architecturaux d’où sont issus les fragments tomitains.
On a lot of roman pottery fragments from the site in Zimnicea
Authors:   The National Museum for the History of Transylvania, Cluj-Napoca, Popescu Mariana-Cristina
Published: October 2022

The article presents a lot of 68 ceramic fragments in the National Museum of Antiquities patrimony which were apparently discovered at Zimnicea in the 1924 campaign. The identified forms, the production centres/production areas and their chronology open the possibility that Zimnicea was also inhabited in Roman times, sometime during the 2nd – 3rd centuries AD.
A Case Study on the Growth of Rural Banking in India
Authors: Shetty Megha D. , Bhat Sudhindra
Published: October 2022

Purpose: In India, rural banking has played a very important role in advancing technology and balancing the economy. The main aim of rural banking is to provide easy access to financial services for the rural population, which is typically underserved by the formal banking sector. The main goal of this paper is to throw light on RRBs and their contribution to the Indian banking system and economy, to compare the growth of amalgamation and presents standalone RRBs, and to identify the problems faced by RRBs by evaluating their performance over the years.
Design/ Methodology Approach: The study is grounded on basis of the Secondary data. The secondary data was gathered from a variety of public and unpublished sources, including websites, books, journals, magazines, newspapers, Reserve Bank of India annual reports, and research papers.
Findings: The study observed that there has been growth in terms of the number of branches and their Performance. The efficiency to expand and finance to rural areas people have increased. The new systems of amalgamation have improved banks’ maintenance and expansion in terms of work.
Originality/ Value: The study is an attempt to give an outline history of the RRBs as well as the performance or growth of RRBs as a result of amalgamation.
Paper Type: Research Case Study based on industry analysis.