bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGUATAN MANAJEMEN SYARIAH MELALUI TOTAL QUALITY MANAGEMENTBAGI PELAKU LEMBAGA KEUANGAN SYARIAH DI KOTA SEMARANG
Authors: Arifin Johan
Published: August 2017

One of the problems that arise in the Islamic financial management is the governance model (management) used are the same as a conventional financial institution management in general, Therefore we need innovation in management. Management Implementation of Sharia in the Islamic financial institutions are expected to improve the performance and quality of these institutions. Implementation of sharia management really comes down to the issue of Total Quality Management (TQM) on financial institutions syar'iah focused on the process of continuous improvement to uphold the values of Shariah.
Management of sharia is considered important in the company since its implementation in the areas of services and operating in personal competence, maintaining the availability of knowledge and innovation as well as product development. Through sharia management is expected to increase the skills and motivation to work on giliranyya will improve the reinforcement of the operational side. The perpetrator of Islamic financial institutions in terms of technical skills are adequate but the problem is the knowledge of the management of sharia. Knowledge management in Islamic financial institutions will be judged by the public that the management is not different from the conventional financial institutions.
PENGEMBANGAN MODUL KIMIA DASAR BERBASIS MULTIPEL LEVEL REPRESENTASI UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS MAHASISWA
Authors: Rahmawati Atik
Published: August 2017

Rendahnya kemampuan mahasiswa yang mengikuti kuliah Kimia Dasar dalam merepresentasikan konsep-konsep kimia pada keempat level representasi kimia, serta belum tersedianya bahan ajar yang merepresentasikan konsep-konsep kimia pada keempat level representasi, mendorong peneliti untuk mengembangkan modul Kimia Dasar berbasis multipel level representasi kimia. Tujuan dari penelitian ini  adalah : a. Bagaimana desain dan sistematika modul kimia dasar berbasis multipel level representasi kimia pada materi stoikiometri untuk meningkatkan kemampuan berpikir kritis mahasiswa? b. Bagaimana kelayakan modul kimia dasar berbasis multipel level representasi kimia, ditinjau dari validasi ahli?Jenis penelitian ini adalah penelitian dan pengembangan. Model pengembangan mengikuti model Thiagarajan 4-D yang  memiliki 4 tahap utama yaitu Define, Design, Develop, dan Disseminate.Hasil penelitian dan pengembangan telah dihasilkan Modul Kimia Dasar berbasis Multipel Level Representasi dengan susunan sebagai berikut : cover, petunjuk penggunaan modul, tujuan pembelajaran, Kegiatan Belajar 1 (meliputi materi konsep massa atom, massa atom relatif rata-rata dan massa molekul relatif rata-rata; persamaan reaksi kimia; konsep mol; persen komposisi senyawa; penentuan rumus empiris dan rumus molekul; pereaksi pembatas; dan persen hasil). Pada Kegiatan Belajar 2 materinya meliputi larutan, konsentrasi larutan, pembuatan kelarutan dengan kemolaran tertentu, pengenceran larutan, stoikiometri larutan (analisis gravimetri, titrasi asam-basa). Setiap materi dilengkapi dengan contoh soal, latihan yuk, dan uji kompetensi. Modul dilengkapi dengan gambar yang dapat menjelaskan konsep kimia skala makroskopis pada level mikroskopis dan simbolis, serta interkoneksi antar ketiga level representasi kimia tersebut sehingga dapat meningkatkan kemampuan berpikir kritis mahasiswa.Penilaian kelayakan (validasi) modul kimia dasar berbasis multipel level representasi kimia oleh ahli menunjukkan bahwa draft modul dalam kategori sangat baik dan baik sehingga tidak perlu dilakukan revisi.
KEBERSAMAN DALAM PEMBELAJARAN MATEMATIKA BERBANTUAN TIK
Authors: Prayitno Edi
Published: August 2017

Semangat kebersamaan merupakan salah satu karakter yang mendukung kesiapan sumber daya manusia menghadapi Masyarakan Ekonomi ASEAN. Pembelajaran matematika yang kooperatif dengan bantuan TIK mendukung peningkatan semangat kebersamaan di antara para peserta didik. Simpulan ini diperoleh dari hasil penelitian pemanfaatan TIK dalam pembelajaran matematika di SMA 4 Semarang tahun 2014. Pola pembelajaran mengalokasikan 2/3 waktu (60 menit) pembelajaran untuk kegiatan kolaboratif mandiri dalam bentuk kerja kelompok. Pembelajaran menampilkan kompetensi dasar “Penentuan volume benda putar”. Guru sepenuhnya bertindak sebagai fasilitator dan mediator dalam pembelajaran. Dalam kerja kelompok para peserta didik berkolaborasi memahami uraian kompetensi dasar, memahami konsep benda putar, memahami konsep volum benda putar dan berlatih menyelesaikan soal. Interaksi selama kerja kelompok dilaksanakan menurut rambu-rambu yang telah ditentukan guru. Rambu-rambu dibuat untuk menghindari munculnya dominasi interaksi oleh satu atau beberapa peserta didik yang lebih dominan dalam kemampuan berkomunikasi atau dalam kemampuan penguasaan materi. Tiap kelompok kerja terdiri dari 3-4 peserta didik dengan kemampuan yang beragam, mulai dari yang paling menguasai materi prasyarat sampai yang paling tidak menguasai materi. Rambu-rambu antara lain menyebutkan bahwa dalam diskusi kelompok peserta didik secara bergantian mendapat giliran pertama mengutarakan pendapat atau menjawab pertanyaan; giliran untuk menanggapi pembicara pertama juga dilakukan oleh peserta didik secara bergantian sesuai rotasi yang telah ditentukan. Selain untuk menjaga kebersamaan, rambu-rambu ini juga menjamin hak dan kewajiban yang sama kepada seluruh anggota kelompok untuk mempersiapkan materi dan bertanggung jawab atas nama kelompok dalam memberi jawaban atau mengungkapkan pendapat.
PENGEMBANGAN PORTAL “CHANNEL PEMBELAJARAN SAINS” SEBAGAI VIDEO PEMBELAJARAN ONLINE MELALUI MODEL ADDIE (ANALYSIS, DESIGN, DEVELOPMENT,IMPLEMENTATION AND EVALUATION )
Authors: Arsini Arsini
Published: August 2017

Penelitian ini  bertujuan untuk mengembangkan Portal “ Channel Pembelajaran Sains” sebagai media pembelajaran online berbasis video yang dapat diakses secara global dan untuk meningkatkan ketersediaan sumber belajar online bagi para guru dan peserta didik  berupa Portal” Channel Pembelajaran Sains” yang berisi berbagai video pembelajaran sains.            Metode yang akan digunakan dalam penelitian ini adalah Research and Development (RD) menggunakan ADDIE Model. Melalui siklus ADDIE Model, yaitu : (1)Analysis, (2)Design, (3)Development, (4)Implementation dan (5) Evaluation akan dikembangkan Portal “Channel Pembelajaran Sains”, sebuah Portal yang didesain sebagai media pembelajaran berbasis video yang dapat diakses melalui internet.            Secara garis besar, penelitian ini terdiri dari sembilan tahap kegiatan. Tahap pertama, analisis materi pembelajaran sains yang sesuai untuk ditampilkan dengan menggunakan media video. Tahap kedua, pengambilan gambar dengan menggunakan Digital Video Shooting. Tahap ketiga, proses editing video menggunakan program aplikasi VideoPad Video Editor . Tahap keempat, mengunggah video ke internet dengan membuat sebuah channel di Portal berbagi video Youtube yang kemudian diberi nama Portal “Channel Pembelajaran Sains”. Tahap kelima, proses validasi media ke berbagai ahli (ahli komunikasi, ahli materi dan ahli media). Tahap keenam, revisi produk berdasarkan masukan para ahli. Tahap ketujuh, uji coba terbatas di sejumlah sekolah untuk memperoleh masukan dari guru dan peserta didik. Tahap kedelapan, revisi berdasarkan masukan dari guru dan peserta didik. Tahap kesembilan, uji coba produk akhir.
PEMANFAATAN MEDIA BELAJAR POWERPOINT UNTUK MENINGKATKAN HASIL BELAJAR IPA SISWA KELAS VII B SEMESTER 2 TAHUN 2015 SMP NEGERI 3 BANYUBIRU
Authors: Purnomo Purnomo
Published: August 2017

Media PowerPoint adalah merupakan media belajar yang dapat membantu guru dalam menyampaikan materi kepada siswa. Permasalahan yang muncul adalah apakah pemanfaatan media belajar PowerPoint dapat meningkatkan hasil belajar  IPA  pada konsep gerak. Penelitian dilakukan pada VIIB  SMPN 3 Banyubiru Semester 2 Tahun Pelajaran 2014/2015 dengan dua siklus. Hasil penelitian menunjukkan bahwa ada peningkatan prestasi belajar IPA pada konsep gerak yaitu dari rata-rata nilai pada siklus I 70,33 menjadi 70,67  pada siklus II
PENGGUNAAN METODE PEMBELAJARAN ROLE PLAYING DALAM MENINGKATKAN KEMAMPUAN BERHITUNG PENJUMLAHAN DAN PENGURANGAN PADA SISWA KELAS VI SLB C1 DHARMA MULIA SEMARANG
Authors: Wahyuningsih Sri Lestari
Published: August 2017

Hasil pengamatan sementara yang dilakukan di SLB C1, khususnya pada anak kelas VI SLB C1 Dharma Mulia Semarang, secara umum siswa memiliki kemampuan berhitung penjumlahan dan pengurangan rendah. Kondisi tersebut menggambarkan rendahnya perkembangan rendahnya perkembangan kognitif siswa SLB C1 Dharma Mulia Semarang.Penelitian ini adalah penelitian tindakan kelas dengan menggunakan model pembelajaran  role playing pada mata pelajaran Matematika yaitu berhitung penjumlahan dan  pengurangan.Kondisi Awal diperoleh ketuntasan klasikal 3/4 x 100% = 75% hanya mencapai 25% yang dapat mencapai ketuntasan atau sebesar 75% belum  tuntas. Siklus I diperoleh ketuntasan klasikal yang mampu dicapai siswa 2/4 x 100% = 50%, yaitu sebanyak 50% siswa mencapai ketuntasan, masih menunjukkan nilai lebih rendah dari ketetapan ketuntasan klasikal, yaitu 100%. Siklus II diperoleh ketuntasan klasikal 100% siswa kelas VI SLB C/C1 Dharma Mulia Semarang  dapat mencapai ketuntasan. Sehingga penggunaan metode pembelajaran role playing dengan yang tepat dapat meningkatkan hasil belajar siswa kelas V SLB C1/C1 Dharma Mulia Semarang pada mata pelajaran Matematika.
Perbandingan Aktivitas Pemodelan dengan Pendekatan Analitik dan Pendekatan Konstruktif untuk Siswa SMA di Yogyakarta
Authors: Nova Andriani Anggi Catur Saputri Florentina
Published: August 2017

Penelitian ini bertujuan untuk membandingkan antara pendekatan analitik dan konstruktif dalam aktivitas pemodelan suatu masalah matematika serta melihat pendekatan mana yang dapat membuat siswa berpikir logis, kritis dan sistematis. Penelitian ini, dilakukan dengan mengambil 7 siswa sebagai sampel random dari populasi siswa kelas XI SMA di Yogyakarta kemudian membagi menjadi dua kelompok. Kelompok pertama menyelesaikan masalah yang diberikan dengan pendekatan analitik sedangkan kelompok lain menggunakan pendekatan konstruktif. Data hasil penelitian ini berupa deskripsi proses penyelesaian masalah matematika dan hasil pekerjaan yang dilakukan oleh kedua kelompok. Hasil dari penelitian ini, siswa yang menggunakan pendekatan analitik terlihat logis, sistematis namun kurang kritis karena terlalu banyak bertanya dan menunggu arahan. Siswa tidak memeriksa kembali hasil pekerjaannya. Sedangkan, siswa dengan pendekatan konstruktif cukup logis, kritis namun terkadang kurang sistematis. Siswa mengerjakan berdasarkan pemahamannya terhadap masalah yang diberikan. Setelah menyelesaikan soal siswa memeriksa kembali hasil pekerjaannya.
KEEFEKTIFAN PENDEKATAN CTL TERHADAP HASIL BELAJAR IPA MATERI SUMBER DAYA ALAM
Authors: Setyowati Desi Wulandari Nuning
Published: August 2017

Penelitian in bertujuan untuk mengkaji keefektifan pendekatan Contextual Teaching and Learning terhadap hasil belajar IPA materi sumber daya alam kelas IV SDN Wonosari 01. Jenis penelitian yang digunakan adalah eksperimen kuasi (quasi experimental) dengan desain Nonequivalent Control Group Design. Subjek penelitian adalah seluruh siswa kelas IV SDN Wonosari 01. Sampel yang digunakan adalah siswa kelas IVA (kelas eksperimen) dan siswa kelas IVB (kelas kontrol). Teknik pengambilan sampel menggunakan teknik sampling jenuh. Penelitian ini adalah penelitian populasi. Data hasil belajar siswa menunjukkan bahwa rata-rata nilai posttest kelas eksperimen lebih besar dibandingkan kelas kontrol. Mean posttest kelas eksperimen sebesar 73,45 dan mean posttest kelas kontrol sebesar 57. Hasil uji-t menunjukkan nilai thitung (4,707) ttabel (1,728) berarti bahwa hasil belajar siswa dengan menggunakan pendekatan CTL lebih besar dibandingkan pendekatan konvensional. Nilai N-Gain kelas kontrol sebesar 0,26 (rendah) dan kelas eksperimen 0,50 (sedang). Hasil tersebut memberikan kesimpulan bahwa pendekatan CTL lebih efektif dibandingkan pendekatan konvensional.
PENGELOLAAN ZAKAT PERTANIAN DI LAZIS NU KABUPATEN KENDAL
Authors: Hakim Abdul
Published: August 2017

In Kendal, at least three social religious institutions that have influence in the community of Kendal, Nahdlatul Ulama (NU), Muhammadiyah, and Rifaiyyah.. Among the three institutions, Nahdlatul Ulama (NU) has the most members spread across the region Kendal, particularly among the farming community. Ideally, NU was able to encourage its members to carry out agricultural zakat. Especially in the NU Community has an institutions, LAZIS (Institution for Managerial Zakat and Shodaqoh). But in reality, of the amount of NU LAZIS scattered in the district of Kendal, only five LAZIS that optimally perform zakat empowerment of agriculture, namely District Rowosari, District Patebon, District Gemuh, District Kangkung, and District Boja. Its implementation is not maximized in the districts but still only focused on areas of the village or certain villages Management and organization become a serious problem in the utilization of zakat agriculture . Zakat management of agriculture focused on aspects of the collection and utilization . Organizational aspects can be solved by internal and external solutions through communication , mapping mustahik and internal consolidation with LAZIS - LAZIS NU in its territory.

Keywords: Management, Agricultural Zakat, LAZIS
FIQH SOSIAL KIAI SAHAL SEBAGAI FIQH PERADABAN
Authors: Asmani Jamal Ma'mur
Published: August 2017

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Improving ANN model performance in runoff forecasting by adding soil moisture input and using data preprocessing techniques
Authors: Ba Huanhuan , Guo Shenglian , Wang Yun , Hong Xingjun , Zhong Yixuan , Liu Zhangjun
Published: August 2017

This study attempts to improve the accuracy of runoff forecasting from two aspects: one is the inclusion of soil moisture time series simulated from the GR4J conceptual rainfall–runoff model as (ANN) input; the other is preprocessing original data series by singular spectrum analysis (SSA). Three watersheds in China were selected as case studies and the ANN1 model only with runoff and rainfall as inputs without data preprocessing was used to be the benchmark. The ANN2 model with soil moisture as an additional input, the SSA-ANN1 and SSA-ANN2 models with the same inputs as ANN1 and ANN2 using data preprocessing were studied. It is revealed that the degree of improvement by SSA is more significant than by the inclusion of soil moisture. Among the four studied models, the SSA-ANN2 model performs the best.
Investigating the development of shallow snowpacks on arable land, using comprehensive field observations and spatially distributed snow modelling
Authors: Starkloff Torsten , Stolte Jannes , Hessel Rudi , Ritsema Coen
Published: August 2017

Shallow (<1 m deep) snowpacks on agricultural areas are an important hydrological component in many countries, which determines how much meltwater is potentially available for overland flow, causing soil erosion and flooding at the end of winter. Therefore, it is important to understand the development of shallow snowpacks in a spatially distributed manner. This study combined field observations with spatially distributed snow modelling using the UEBGrid model, for three consecutive winters (2013–2015) in southern Norway. Model performance was evaluated by comparing the spatially distributed snow water equivalent (SWE) measurements over time with the simulated SWE. UEBGrid replicated SWE development at catchment scale with satisfactory accuracy for the three winters. The different calibration approaches which were necessary for winters 2013 and 2015 showed the delicacy of modelling the change in shallow snowpacks. Especially the refreezing of meltwater and prevention of runoff and infiltration of meltwater by frozen soils and ice layers can make simulations of shallow snowpacks challenging.
Optimal dewatering of an excavation site by using the linked simulation–optimization approaches
Authors: Ayvaz M. Tamer
Published: August 2017

In this study, a linked simulation–optimization approach is proposed for optimal dewatering system design for an excavation site. In the simulation part of the proposed approach, an analytical groundwater flow model is used to simulate the flow process in the subsurface. This model is then integrated with two different optimization models where differential evolution (DE) and harmony search (HS) optimization algorithms are used. The objectives of both models are to determine the best dewatering system configuration by considering locations and pumping rates as decision variables. During the search process, the constraints related to drawdown and well locations are included in the optimization by using the penalty function approach. The performance of DE- and HS-based solution approaches is evaluated on a hypothetical excavation site for different well numbers. Identified results indicated that the DE-based solution approach provides slightly better results than those obtained by using the HS-based solution approach.
Developmental anomalies affecting the morphology of teeth – a review
Authors: Shrestha Ashish , Marla Vinay , Shrestha Sushmita , Maharjan Iccha K.
Published: August 2017

Introduction: The development of tooth is a complex process wherein there is series of interactions between the ectoderm and ectomesenchyme. The role of genes in determining the shape and form of a specific tooth has already been defined, the alterations in which can lead to a variety of anomalies in regards to number, size, form, shape, structure, etc. Objective: To review the literature on the developmental anomalies of teeth. Literature review: The developmental anomalies affecting the morphology exists in both deciduous & permanent dentition and shows various forms such as gemination, fusion, concrescence, dilacerations, dens evaginatus, dens invaginatus, enamel pearls, taurodontism or peg laterals. These anomalies have clinical significance concerning esthetics, malocclusion and more importantly predisposing the development of dental caries and periodontal diseases. Conclusion: Knowledge of various diagnostic criteria for identification of these developmental anomalies is significant for early diagnosis and pertinent treatment.
Indications and restorative techniques for glass ionomer cement
Authors: Piola Rizzante Fabio Antonio , Cunali Rafael Schlögel , Fraga Soares Bombonatti Juliana , Correr Gisele Maria , Gonzaga Carla Castiglia , Furuse Adilson Yoshio
Published: August 2017

Introduction: Due to its chemical, mechanical and biological properties, the glass ionomer cements (GIC) consist in one of the most versatile direct restorative materials, with many potential clinical indications, especially in the context of minimally invasive dentistry. Nevertheless, they have some limitations and require the knowledge of their characteristics and procedures of application in order to achieve their maximum potential. Objective: To demonstrate through literature review the main characteristics, indications, limitations and future perspectives for the use of GIC. Literature review: The database, such as Pubmed and Lilacs were used. Additionally, books were also evaluated and included. Conclusion: The GIC is in constant evolution and is one of the materials that are best suited in the context of preventive and conservative dentistry. It has satisfactory properties and versatility. On the other hand, presents inferior properties when compared to other direct restorative materials, requiring caution during its handling.
Chronic maxillary osteomyelitis secondary to chronic maxillary sinusitis in non-immunocompromised patient – a rare case report and its management
Authors: Narsapur Sulabha A. , Choudhari Sameer , Pasha Zameer
Published: August 2017

Osteomyelitis is an inflammation of medullary portion of bone along with cortex and periosteum. It is one of most difficult infectious diseases to treat. Facial bones are prone to osteomyelitis due to various predisposing condition. Osteomyelitis of maxilla is rare disease and less frequently encountered. Objective: The aim of the article is to present an unusual case of chronic maxillary osteomyelitis secondary to rhinogenic which are rarely clinically causes. Case report: We hereby report a case of chronic maxillary osteomyelitis in 70-year-old non-immunocompromised patient secondary to chronic maxillary sinusitis. Complete resolution of chronic maxillary osteomyelitis was achieved by combination of antimicrobial therapy and surgical treatment. Conclusion: Clinician should identify such risk and provide the aggressive treatment modalities to avoid subsequent dreaded consequences.
Beliefs in relation to elderly between Dentistry undergraduates of private university of Parana
Authors: Koch-Filho Herbert Rubens , Beiger Luis Fernando , Mendes Matheus Augusto
Published: August 2017

Introduction: Aging is a sociocultural concept characterized by the opposite to the youth. Generalization and the lack of knowledge about this stage of life can lead to false assessments that tend to oscillate between positive and negative. Objective: a) To characterize the beliefs about aging of Dentistry undergraduates from a private higher education institution; b) to verify if the belief of the undergraduates had about aging may interfere in the choice of future dental care given to older people, and; c) to assess the profile of the respondents by gender, age and graduation period. Material and methods: This cross-sectionaldescriptive study was conducted with students properly enrolled in the Dentistry course of a private institution, in 2016 (N = 90). The profile of the population was defined by gender, age and graduation period. It was verified the preference and predilection in future working or not working with a certain age group. Also, the beliefs about aging were investigated through a semantic scale. Distributions of absolute and relative frequencies were made. Statistical analysis was given by using SPSS version 20.0. Results: Most respondents were female (78.9%); with a mean age of 23.34 years; enrolled in the 8th period; 51.1% said they had no preference in future work with particular age range; and, there was a predominance of positive view, with tendencies towards neutrality. There were no statistically significant differences between the beliefs toward aging and the variables: gender, age and period. Statistically significant dependencies were found between the beliefs about old age and preference in working or not working in future treat a certain age range of the population. Conclusion: Therespondents have a more positive view of old age; no predilection to provide dental care to a certain age group, highlighting a general and humanist profile in relation to chronological age.
Oral rehabilitation with removable dental prosthesis in a six-year-old patient with hypohidrotic ectodermal dysplasia
Authors: Dalledone Mariana , De Paiva Bertoli Fernanda Mara , Sponchiado Ana Paula , Losso Estela Maris , Brancher João Armando , De Souza Juliana Feltrin
Published: August 2017

Introduction: Ectodermal dysplasia is an abnormality of the ectoderm and its derivatives, phenotypically expressed in males and genetically inherited from mothers. Objective: To report the efficacy of the prosthetics treatment of severe ectodermal dysplasia in a 6-year-old boy with hypohidrotic ectodermal dysplasia (HED). Case report: The boy had difficulty in speaking and eating and the condition also affected his self-esteem. Prosthetic treatments included the construction of acrylic custom trays, determination of the vertical dimension of occlusion (VDO), construction of upper and lower dentures, and palatal expansion procedure. Conclusion: Significant improvements in the patient’s stomatognathic functionand self-esteem were evident.
Periodontal plastic surgery for treatment of gummy smile with cosmetic restauration treatment
Authors: Gonçalves Keith Jimmy , Agnoletto Gabrielle Gobbo , Da Cunha Leonardo Fernandes , Storrer Carmen Mueller , Deliberador Tatiana Miranda
Published: August 2017

Introduction: Today, the appreciation of aesthetic dentistry by society brought to the search for materials and techniques that improve the appearance of smile, which is essential in maintaining physical and mental health of the patient. Objective: This study aimed to report a case of gummy smile involving Periodontics and Restorative Dentistry. Case report: This case, despite other possible alternatives, was solved through periodontal surgery (clinical crown augmentation associated with osteotomy) and indirect restorations with porcelain crowns. Conclusion: In our experience this procedure is safe, predictable, with minimal risks or side effects, and it is a treatment option for these cases.
Topical Formulations and Intradermal Injections of Tranexamic Acid in the Treatment of Hyperpigmentation - A Review
Authors: Batory Mirella , Rotsztejn Helena
Published: August 2017

Background:

The anti-plasmin activity of Tranexamic Acid (TA) is considered to be the
main mechanism of hypopigmentation. Several studies have found TA to be effective for both oral
and topical application. When used to lighten stains, TA is effective even at low concentrations,
ideally in the range of 2 to 5%. Increasing the duration of treatment is more effective than increasing
the concentration of TA: Higher concentrations of TA (> 5%) do not improve the effect but
rather cause irritation. The TA formulations were applied once or twice a day, and the average duration
was eight to twelve weeks: advantageous therapeutic effects were observed after this period.
Other studies gave intradermal injections once weekly for 12 weeks, also with an acceptable efficiency.
The compound may be administered topically to the skin in the form of emulsions, creams
and solutions, and formulations containing liposomes. Encapsulation of TA in liposomes may reduce
potential skin irritation, and it ensure high formulation stability, decrease the risk of leakage
and allow long-term sustained release. Intradermal injections of TA produce relatively quick
bleaching results without significant side effects.

Conclusion:

In conclusion it should be stated that the lightening effect of tranexamic acid in topical
and intradermal applications has been most extensively studied in the case of melasma, and most
studies have been performed in Asia. Therefore, the final evaluation of TA, in the cases other than
melasma and hyperpigmentation, requires further studies. However, further studies are needed in
order to optimize the frequency of application of TA and to determine the long-term benefits from
its use, especially concerning stains other than chloasma.
QSAR Studies on NTF1836 Analogues as Mycothiol Biosynthesis Inhibitors
Authors: Kathiravan M.K. , Nilewar S.S. , Kale A.N.
Published: August 2017

Background: Mycothiol (MSH), a thiol compound found in Mycobacterium tuberculosis
is required for the growth and survival of bacteria. This unusual compound is found only in actinomycetes.
MSH biosynthesis involves many enzymes, one of them is MshC an essential enzyme for
M. tuberculosis.

Methods: NTF1836 were the first MSH biosynthesis inhibitors identified. QSAR studies
were performed on a novel series of NTF1836 as an inhibitor of MshC (enzyme involved in the
synthesis of mycothiol). The series of molecules were subjected to CoMFA, CoMSIA and HQSAR
studies.

Results: The resulted model exhibited good correlation coefficient (r2) of 0.98, 0.87, 0.81 and cross
validated correlation coefficient (q2) of 0.76, 0.60, and 0.61 for CoMFA, CoMSIA and HQSAR
methods respectively. Contour map analysis revealed the importance of steric, electrostatic, donor,
acceptor and hydrophobic fields in determining the activity.

Conclusion: The results of our structure activity relationships study reveals key contribution and
can serve as a basis for future drug development of antitubercular agent.
Novel Azole-Functionalited Flouroquinolone Hybrids: Design, Conventional and Microwave Irradiated Synthesis, Evaluation as Antibacterial and Antioxidant Agents
Authors: Mentese Meltem , Demirbas Neslihan , Mermer Arif , Demirci Serpil , Demirbas Ahmet , Ayaz Faik Ahmet
Published: August 2017

Background:

The synthesis of new hybrid molecules consisting of several heterocyclic
pharmacophores namely fluoroquinolone, 1,2,4-triazole, 1,3,4-oxadiazole and piperazine was carried
out by conventional and successfully optimized microwave mediated techniques.

Methods:

The structures of new compounds were confirmed using spectroscopic techniques. These
compounds were screened for their antibacterial activity against E. coli, P. aeruginosa, Y. pseudotuberculosis,
S. aureus, E. faecalis, B. cereus and M. smegmatis.

Results and Conclusion:

Fourteen of these hybrids exhibited excellent antibacterial activities on
the test microorganisms when compared with ampicillin with the mic values varying between 0.03-
0.25 µg/mL.
Teleophthalmology in Practice: Lessons Learned from a Pilot Project
Authors: Ayatollahi Haleh , Nourani Aynaz , Khodaveisi Taleb , Aghaei Hossein , Mohammadpour Mehrdad
Published: August 2017

Introduction:

Ophthalmology is a medical specialty which may benefit from using telemedicine and teleophthalmology services. Such services are significantly important in the poor, remote, and impassable geographical areas, where there is no access to the ophthalmology services and ophthalmologists. This study aimed to design and implement a teleophthalmology system using the method of store-and-forward.

Methods:

The study was conducted in 2015 and consisted of two main phases. The first phase was based requirement analysis, and in the second phase, after designing the prototype, an initial usability testing was undertaken in a teaching hospital. The participants of the study were 10 optometrists and 10 ophthalmologists (cornea specialists). For each phase of the research, a questionnaire was used to collect data, and the collected data were analyzed using descriptive statistics.

Results:

In this study, users’ requirements were initially investigated. Then, the teleophthalmology system was designed based on the literature review and the results derived from the requirements’ analysis. Finally, usability testing showed that the users were relatively satisfied with the system.

Conclusion:

According to the results, it can be concluded that the teleophthalmology technology can be used in the country by optometrists and ophthalmologists to improve eye health care services and to prevent the prevalence of curable eye diseases.
Contextual-Based Knowledge Creation for Agroindustrial Innovation
Authors: Anggraeni Elisa , Machfud Machfud , Maarif Mohamad Syamsul , Harjomidjojo Hartrisari
Published: August 2017

This paper discusses the knowledge creation process in one department, in a higher educational context, and the possible actions to take to improve the efficiency and effectiveness of the knowledge creation system in it. We conducted a case study at one department of a university that strives to improve its innovations, in terms of their quantity and quality.We used a soft system methodology to investigate the knowledge creation system in the chosen department. From the study, we conclude that the department can be considered as a learning organization, within which its staff continually create, acquire and transfer knowledge. This department has a learning environment which is conducive, concrete learning processes, and leadership that reinforces learning. In the context of producing agroindustry innovations, the knowledge creation system in this department is considered to be less effective since it frequently happens more at individual or small group levels. To improve its effectiveness, the management may facilitate the institutionalization of knowledge creation processes at every phase of the interactions between tacit and explicit knowledge.
The Volatility–Variability Hypotheses Testing and Hedging Effectiveness of Precious Metals for the Indonesian and Malaysian Capital Markets
Authors: Robiyanto Robiyanto , Wahyudi Sugeng , Pangestuti Irene Rini Demi
Published: August 2017

This study evaluates the use of futures contracts for precious metals to hedge against stock market risks and their hedging effectiveness on the Indonesian Stock Exchange (IDX) and the Kuala Lumpur Stock Exchange (KLSE). This study found that gold was the most effective hedging instrument, since it produced the highest hedging effectiveness both on the IDX and the KLSE among the other precious metals. None of the hedged portfolios had a higher Sharpe’s ratio than the unhedged one on the IDX; however, all the hedged portfolios on the KLSE had a higher Sharpe’s ratio than the unhedged ones. Almost all the hedged portfolios could produce a higher Treynor’s ratio than the unhedged portfolios, both on the IDX and the KLSE. In general, this study concluded that studying some precious metals could reduce the investment risk, which was shown through the variance produced by the smaller portfolios, while gold can improve the risk-adjusted performance.
Housing Development Building Management System (HDBMS) For Optimized Electricity Bills
Authors: Li Weixian , Logenthiran Thillainathan , Phan Van-Tung , Lok Woo Wai
Published: August 2017

Smart Buildings is a modern building that allows residents to have sustainable comfort with high efficiency of electricity usage. These objectives could be achieved by applying appropriate, capable optimization algorithms and techniques. This paper presents a Housing Development Building Management System (HDBMS) strategy inspired by Building Energy Management System (BEMS) concept that will integrate with smart buildings using Supply Side Management (SSM) and Demand Side Management (DSM) System. HDBMS is a Multi-Agent System (MAS) based decentralized decision making system proposed by various authors. MAS based HDBMS was created using JAVA on a IEEE FIPA compliant multi-agent platform named JADE. It allows agents to communicate, interact and negotiate with energy supply and demand of the smart buildings to provide the optimal energy usage and minimal electricity costs.  This results in reducing the load of the power distribution system in smart buildings which simulation studies has shown the potential of proposed HDBMS strategy to provide the optimal solution for smart building energy management.
Influences of Breakfast on Clock Gene Expression and Postprandial Glycemia in Healthy Individuals and Individuals With Diabetes: A Randomized Clinical Trial
Authors: Jakubowicz Daniela , Wainstein Julio , Landau Zohar , Raz Itamar , Ahren Bo , Chapnik Nava , Ganz Tali , Menaged Miriam , Barnea Maayan , Bar-Dayan Yosefa , Froy Oren
Published: August 2017

OBJECTIVE

The circadian clock regulates glucose metabolism by mediating the activity of metabolic enzymes, hormones, and transport systems. Breakfast skipping and night eating have been associated with high HbA1c and postprandial hyperglycemia after lunch and dinner. Our aim was to explore the acute effect of breakfast consumption or omission on glucose homeostasis and clock gene expression in healthy individuals and individuals with type 2 diabetes.

RESEARCH DESIGN AND METHODS

In a crossover design, 18 healthy volunteers and 18 volunteers with 14.5 ± 1.5 years diabetes, BMI 30.7 ± 1.1 kg/m2, and HbA1c 7.6 ± 0.1% (59.6 ± 0.8 mmol/mol) were randomly assigned to a test day with breakfast and lunch (YesB) and a test day with only lunch (NoB). Postprandial clock and clock-controlled gene expression, plasma glucose, insulin, intact glucagon-like peptide 1 (iGLP-1), and dipeptidyl peptidase IV (DPP-IV) plasma activity were assessed after breakfast and lunch.

RESULTS

In healthy individuals, the expression level of Per1, Cry1, Rorα, and Sirt1 was lower (P < 0.05) but Clock was higher (P < 0.05) after breakfast. In contrast, in individuals with type 2 diabetes, Per1, Per2, and Sirt1 only slightly, but significantly, decreased and Rorα increased (P < 0.05) after breakfast. In healthy individuals, the expression level of Bmal1, Rorα, and Sirt1 was higher (P < 0.05) after lunch on YesB day, whereas the other clock genes remained unchanged. In individuals with type 2 diabetes, Bmal1, Per1, Per2, Rev-erbα, and Ampk increased (P < 0.05) after lunch on the YesB day. Omission of breakfast altered clock and metabolic gene expression in both healthy and individuals with type 2 diabetes.

CONCLUSIONS

Breakfast consumption acutely affects clock and clock-controlled gene expression leading to normal oscillation. Breakfast skipping adversely affects clock and clock-controlled gene expression and is correlated with increased postprandial glycemic response in both healthy individuals and individuals with diabetes.
Tuotantokäyttöön soveltuva edullinen menetelmä hitsin juuren puolen väsymiseliniän arvioimiseksi
Authors: Valkonen Ilkka , Valkonen Antti
Published: August 2017

Juuren puolen väsyminen on käytännössä erityisen ongelmallinen syystä, että vauriota ei voi havaita ennenkuin särö on edennyt hitsin läpi. Analyysimenetelmistä esimerkiksi ns. Hot-Spot menetelmä ei sovellu juuren puolen väsymisen arviointiin.

Eurocode kolmessa on joitain tapauksia, jotka käytännössä ovat juuren puolen säröön liittyviä, mutta yleistä käyttökelpoista menetelmää ei ole aikaisemmin esiintynyt. Viime vuosina on kyseisen ongelman ratkaisuun esitetty tehollisen loven menetelmää (ENS, "Effective Notch Stress"), jossa juurivirhe mallinnetaan ja virheen päissä kytetään 1 mm säteistä kaarta.

Elementtimenetelmään on uutena yleisempään tietoisuuteen tullut alkujaan Belytschkon ja hänen ryhmänsä kehittämä XFEM, jolla pystyy mallintamaan särön elementtiverkosta riippumatta. Tämä antaa teoriassa hyvän mahdollisuuden tuotantokäyttöön soveltuvan analyysimenetelmän pohjaksi.

Tämän esityksen tarkoituksena on verrata nimellisen jännityksen menetelmää, ENS-menetelmää, sekä XFEM-murtumismekaniikan käyttöä juuren puolen väsymisen arviointiin.
Nodular Cast Iron ONERA Fatigue Model Fitting
Authors: Kumpula Asko , Vaara Joona , Leppänen Anton , Frondelius Tero
Published: August 2017

ONERA fatigue model identification has been carried out for the nodular cast iron material. Selected fatigue model considers mean stress effect, temperature dependency, multiaxiality and non-linear damage cumulation due to variable amplitude loading. Fitting of model parameters was carried out using the Z-set software package.
Stiffness and strength of a semi-regular lattice
Authors: Their Tomas , St-Pierre Luc
Published: August 2017

Honeycombs and other lattice materials have the advantage that their topology can be designed to achieve unique combinations of properties, such as high strength at low density.  The work presented here is exploratory in nature: we investigated the mechanical properties of a two-dimensional lattice and compared its performances to other topologies.  Analytical expressions for the uniaxial stiffness and compressive strength were developed and validated against Finite Element simulations.  The results showed that the lattice considered is stiffer and stronger than the diamond lattice, and has a higher resistance to elastic buckling than the triangular lattice.
Bayesian Sequential Experimental Design for Fatigue Tests
Authors: Väntänen Miikka , Vaara Joona , Aho Jukka , Kemppainen Jukka , Frondelius Tero
Published: August 2017

A Bayesian sequential experimental design for fatigue testing was implemented on the basis on D-optimality and a non-linear continuous damage model. The design accounts for the whole range of testing levels.
Concept Calculation Tool for Dynamics of Generator Set Common Baseframe
Authors: Heilala Johannes , Kuivaniemi Teemu , Könnö Juho , Frondelius Tero
Published: August 2017

The Natural frequency and vibration response calculation process of a generator set was automatized so that it can be used in a generator set common base frame concept design. The implementation of automatization was to be done so that no profound knowledge about the finite element method is needed to execute calculations and that computation times are short. Substructuring is used for certain parts of the generator set model to reduce the computation times for more a efficient concept design process. The common base frame concept design is implemented to the process by using a design tool in which the finite element model generation from parametric geometry is automatized. Generator set finite element model generation, natural frequency and vibration response calculations and post-processing of analysis results were implemented by developing a calculation tool for this purpose. The calculation tool is an independent application that uses Abaqus simulation software to execute analyses.
Topology optimization of cast iron parts
Authors: Turkkila Timo
Published: August 2017

This article presents experiences of topology optimization. In the example, commercial software is used to find the optimal topology of the cast iron part.
Magneto-structural simulation of an induction motor start-up using nodal magnetic forces in Elmer
Authors: Keränen Janne , Ponomarev Pavel , Sathyan Sabin , Kataja Juhani , Belahcen Anouar
Published: August 2017

For reduction of vibrations and noise of electrical machines, the computation of the magnetic force distributions and the ensuing deformations are needed. Here we utilize nodalforce method in open-source Finite Element software Elmer to compute the force distributions and the vibrations of an induction motor during start-up.
Brief review on high-cycle fatigue with focus on non-metallic inclusions and forming
Authors: Vaara Joona , Mäntylä Antti , Frondelius Tero
Published: August 2017

Professor Y. Murakami has been a dominant gure in the eld of fatigue, pinpointing the most important things for research. However, in order to further improve the prediction methods, knowing the history, discussions and decisions in the fatigue community are necessary. This paper aims to give a brief and historical review on various high-cycle fatigue phenomena focused around non-metallic inclusions and forming.
Topology Optimisation of In-line Engine Turbocharger Bracket
Authors: Kiseleva Evgeniya , Könnö Juho , Luiljenfeldt Niclas , Kuivaniemi Teemu , Frondelius Tero
Published: August 2017

This article describes the use of the TOSCA software in the design process of a turbocharger bracket of a medium speed gas or diesel engine. TOSCA is a topology optimization software from Dassault Systemes. This paper shows some intermediate optimized results as wells as the final design.
Explosion simulation of pressurized components
Authors: Nyberg Mikael , Mäntylä Antti , Frondelius Tero
Published: August 2017

This article describes one simulation study of engine components that operate in an explosion risk zone. High pressure system failures and unfavorable chemical reactions put components in situations not commonly considered in normal dimensioning. From the safety point of view, explosion and damage control involve a wide range of uncertainty factors.
Full scale fatigue testing of crankshaft
Authors: Korhonen Jussi , Mäntylä Antti , Könnö Juho , Frondelius Tero
Published: August 2017

This article outlines full-scale fatigue testing of crankshafts, in particular with the resonance fatigue testing method. The focus of the paper is the practical implementation of the method.
A review on linear switched reluctance motor
Authors: Chowdhury Juan , Kumar Gaurav , Kalita Karuna , Tammi Kari , Kakoty Sashindra K
Published: August 2017

Switched reluctance motors have been extensively studied by researchers for their unparalleled advantages in wide range of applications. The linear versions of it, possessing similar attributes and prospects, have been developed in recent years. Owing to their frugal design, robust built and high force density, the linear switched reluctance motors (LSRM) has had significant stages of development and optimization. The flexibility in design and operation makes LSRM a prime contender for any linear motor-actuator application. This paper provides a bird’s eye view across its developmental stages and its various aspects in design, analysis and control. The following content discusses the salient points of research and the contribution by researchers in this field.
Isogeometric finite element analysis of mode I cracks within strain gradient elasticity
Authors: Niiranen Jarkko , Khakalo Sergei , Balobanov Viacheslav
Published: August 2017

A variational formulation within an H2 Sobolev space setting is formulated for fourth-order plane strain/stress boundary value problems following a widely-used one parameter variant of Mindlin's strain gradient elasticity theory. A corresponding planar mode I crack problem is solved by isogeometric Cp-1-continuous discretizations for NURBS basis functions of order p \ge 2. Stress eld singularities of the classical elasticity are shown to be removed by the strain gradient formulation.
Optimum design of welded structures
Authors: Jarmai Karoly
Published: August 2017

This article presents the cost calculation system developed by us to determine the cost of a welded structure. In the paper the design, fabrication and economy are linked together in the optimization system. Two tubular truss applications show, that the reduction of cost can be significant.
X-liitoksen vinoutumisnurjahdus
Authors: Björk Timo , Tuominen Niko Petteri , Ahola Antti
Published: August 2017

Tutkimuksessa tuodaan esiin uusi vaihtoehto X-liitoksen vaurioitumiselle. Täysleveä puristuskuormitusta kotelomaisesta sauvoista koostuva X-liitos voi menettää kantokykynsä myös vinoutumisnurjahtamalla, jolloin poikittaispalkin poikkileikkaus vinoutuu. Analyyttinen malli perustuu virtuaalisen siirtymän synnyttämän muodonmuutostilan energiatasapainoon.
Suurikaliiperisten aseiden tuliputkien pyörrevirta-tarkastuksen ja ultraäänitarkastuksen mekanisoinnin kehitys ja toteutus
Authors: Moilanen Seppo , Lehtinen Ville
Published: August 2017

Artikkelissa esitetään mekanisoitujen NDT-tarkastuslaitteiden suunnittelu, to­teu­tus sekä tarkastusmenetelmäsuositus raskaiden ruutiaseiden tuliputkien turvallisen eliniän hal­lintaan liittyen. Kra­naa­tin­heittimen tuliputken sileä sisäpinta tarkastetaan kuivana sisäpuolisella pyörre­virta­tarkastuksella (ET). Rihlatun tykinputken tilavuuden ja sisäpinnan tarkastukseen suo­si­tellaan ulkopuolista luotausta ultraääni­menetelmien yhdistelmällä (UT, ToFD) upotuksessa.
RM50 - Thanks to our collaborators
Authors: Kouhia Reijo
Published: August 2017

RM50 - Thanks to our collaborators
Višekriterijumska optimizacija postrojenja za proizvodnju demineralizovane vode iz toplih izvora
Authors: Petrović Andrija , Petrović Aleksandar
Published: August 2017

U radu je predstavljeno postrojenje za demineralizaciju vode iz toplih izvora koje se zasniva na snižavanju pritiska tople vode, primenom ejektora sa pogonom na vodu, u cilju isparavanja iste. Radi određivanja optimalnih vrednosti radnih parametara postrojenja, pre svega pritiska isparavanja, urađena je višekriterijumska optimizacija NSGA II evolutivnim algoritmom između funkcije investicionih troškova i profita. S obzirom na promenu temperature izvorske tople vode u letnjem i zimskom periodu vremena, prihod, a posledično i profit je računat za celu godinu. Na osnovu predstavljenog rezultata može se zaključiti da niži nivo pritiska tople vode povećava vrednost investicije postrojenja, ali isto tako utiče i na povećanje smanjenje prihoda i profita postrojenja. Ovim radom prikazan je novi model bilansiranja postrojenja u cilju dobijanja Pareto fronta, na osnovu kojeg se u zavisnosti od budžeta kojim raspolaže investitor donosi najbolja odluka.