bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 5 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: March 2023

PDF file - 120K, C57Bl/6 mice bearing B16-Ova tumors were injected intratumorally with the respective viruses as described in materials and methods. Lymph nodes, spleens and tumors were collected 8 days after first virus injection, smashed and cultured for 24 hours. Analysis of T-cell markers was performed by flow cytometry for CD3, CD4 and CD8 and plotted as mean +SEM. *, P<0.05.
Supplementary Figure 4 from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: March 2023

PDF file - 11564K, MMP-1 is able to rescue defects in spheroid outgrowth resulting from TWIST1 ablation
Supplementary Figures 1-6 from Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells
Authors: Noman Muhammad Zaeem , Buart Stéphanie , Romero Pedro , Ketari Sami , Janji Bassam , Mari Bernard , Mami-Chouaib Fathia , Chouaib Salem
Published: March 2023

PDF file - 779K, This file contains data showing miRNAs upregulated by hypoxia in IGR-Heu and NA-8 cell lines and miR-210 upregulated under hypoxia in several NSCLC and melanoma cell lines. It also contains figure showing the role of hypoxia induced miR-210 in CTL clone-mediated lysis towards NA-8 cells and the effect of miR-210 on hypoxia-induced factors in IGR-Heu cells. Finally it shows the list of 44 validated miR-210 targets from miRanda and the Enrichment of mir-210 in Argonaute complex after IGR-Heu cells were exposed to hypoxia
Supplementary Figure 3 from Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells
Authors: Du Xiaoli , Qian Xiaolan , Papageorge Alex , Schetter Aaron J. , Vass William C. , Liu Xi , Braverman Richard , Robles Ana I. , Lowy Douglas R.
Published: March 2023

PDF file - 1MB, Expression of CAV1 or the combination of low CAV1 with low DLC1 do not affect the prognostic significance of lung cancer patients in Director's challenge cohort
Supplementary Figure 6 from The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA
Authors: Rabellino Andrea , Carter Brandon , Konstantinidou Georgia , Wu Shwu-Yuan , Rimessi Alessandro , Byers Lauren A. , Heymach John V. , Girard Luc , Chiang Cheng-Ming , Teruya-Feldstein Julie , Scaglioni Pier Paolo
Published: March 2023

PDF file - 105K
Supplementary Figure 2 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer
Authors: Wang Qingfei , Li Shau-Hsuan , Wang Hai , Xiao Yi , Sahin Ozgur , Brady Samuel W. , Li Ping , Ge Hailiang , Jaffee Elizabeth M. , Muller William J. , Hortobagyi Gabriel N. , Yu Dihua
Published: March 2023

PDF file - 25K, HER2/Neu antibody 7.16.4 and Akt inhibitor TCN combination treatment reduced tumor multiplicity and lung metastasis in PTEN-/-/NIC mice
Supplementary Figure 1 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer
Authors: Wang Qingfei , Li Shau-Hsuan , Wang Hai , Xiao Yi , Sahin Ozgur , Brady Samuel W. , Li Ping , Ge Hailiang , Jaffee Elizabeth M. , Muller William J. , Hortobagyi Gabriel N. , Yu Dihua
Published: March 2023

PDF file - 85K, Characterization of PTEN-/-/NIC mouse model
Supplementary Figure 1 from S100A7 Enhances Mammary Tumorigenesis through Upregulation of Inflammatory Pathways
Authors: Nasser Mohd W. , Qamri Zahida , Deol Yadwinder S. , Ravi Janani , Powell Catherine A. , Trikha Prashant , Schwendener Reto A. , Bai Xue-Feng , Shilo Konstantin , Zou Xianghong , Leone Gustavo , Wolf Ronald , Yuspa Stuart H. , Ganju Ramesh K.
Published: March 2023

PDF file - 262K
Supplementary Information from Pak1 Kinase Links ErbB2 to β-Catenin in Transformation of Breast Epithelial Cells
Authors: Arias-Romero Luis E. , Villamar-Cruz Olga , Huang Min , Hoeflich Klaus P. , Chernoff Jonathan
Published: March 2023

PDF File - 184K, p21-activated kinase-1 links ErbB2 to �-catenin in transformation of breast epithelial cells.
Supplementary Methods from p38 MAPK in Myeloma Cells Regulates Osteoclast and Osteoblast Activity and Induces Bone Destruction
Authors: He Jin , Liu Zhiqiang , Zheng Yuhuan , Qian Jianfei , Li Haiyan , Lu Yong , Xu Jingda , Hong Bangxing , Zhang Mingjun , Lin Pei , Cai Zhen , Orlowski Robert Z. , Kwak Larry W. , Yi Qing , Yang Jing
Published: March 2023

PDF file - 96K, Supplemental experimental procedures, including immunohistochemical analysis, western blotting analysis, Real-time PCR, cytokine array, ELISA, in vitro osteoclast and osteoblast formation and activity analysis and statistical analysis
Supplementary Table 2 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer
Authors: Patel Ronil A. , Forinash Kara D. , Pireddu Roberta , Sun Ying , Sun Nan , Martin Mathew P. , Schönbrunn Ernst , Lawrence Nicholas J. , Sebti Saïd M.
Published: March 2023

PDF file, 58K, Percent tumor volume change after mouse treatment with vehicle. ErbB2 mammary tumor transgenic mice were treated with Vehicle (20% HPCD) as described under Materials and Methods. Percent change in tumor volume was calculated for each tumor using the following formula; (Vf-V0)/V0*100; where V0= Initial volume (at the beginning of treatment) and Vf= Final volume (at the end of treatment).
Supplementary Figure 5 from DDX31 Regulates the p53-HDM2 Pathway and rRNA Gene Transcription through Its Interaction with NPM1 in Renal Cell Carcinomas
Authors: Fukawa Tomoya , Ono Masaya , Matsuo Taisuke , Uehara Hisanori , Miki Tsuneharu , Nakamura Yusuke , Kanayama Hiro-omi , Katagiri Toyomasa
Published: March 2023

PDF file - 1.6MB, (A) Effects of doxorubicin-induced cellular stress. NPM1 translocated to the nucleoplasm or cytoplasm in DDX31-depleted RCC cells, but not in siEGFP-transfected cells even under doxorubicin treatment. �iB) NPM1 translocated to nucleoplasm in HK-2 cells under doxorubicin treatment. Scale bar shows 50 mum
Supplementary Figure 4 from DDX31 Regulates the p53-HDM2 Pathway and rRNA Gene Transcription through Its Interaction with NPM1 in Renal Cell Carcinomas
Authors: Fukawa Tomoya , Ono Masaya , Matsuo Taisuke , Uehara Hisanori , Miki Tsuneharu , Nakamura Yusuke , Kanayama Hiro-omi , Katagiri Toyomasa
Published: March 2023

PDF file - 1.2MB, (A) FACS profiles of KMRC-1 (p53 wildtype) cells that were treated with siDDX31 or siEGFP. Cells were harvested with supernatant, stained with propidium iodide and analyzed by flow cytometry at 96 h after transfection. (B) Effects of DDX31 knockdown on cell growth and p53 and/or p21 expression in p53 mutant cell. Quantitative RT-PCR showing the suppression of endogenous DDX31 expression by DDX31 siRNA oligonucleotides (left). MTT assay showed a slight decrease in the cell numbers upon DDX31 knockdown in KMRC-20 (right ).(C) Effects of DDX31 knockdown on p53 and p21 protein levels in KMRC-20
Supplementary Figures 1-3 from Dermatan Sulfate Is Involved in the Tumorigenic Properties of Esophagus Squamous Cell Carcinoma
Authors: Thelin Martin A. , Svensson Katrin J. , Shi Xiaofeng , Bagher Mariam , Axelsson Jakob , Isinger-Ekstrand Anna , van Kuppevelt Toin H. , Johansson Jan , Nilbert Mef , Zaia Joseph , Belting Mattias , Maccarana Marco , Malmström Anders
Published: March 2023

PDF file - 246K
Supplementary Table 1 from RhoJ Regulates Melanoma Chemoresistance by Suppressing Pathways That Sense DNA Damage
Authors: Ho Hsiang , Aruri Jayavani , Kapadia Rubina , Mehr Hootan , White Michael A. , Ganesan Anand K.
Published: March 2023

XLS file - 9MB, genome-wide RNAi dataset
Supplementary Table 4 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: March 2023

XLS file - 53K, Ingenuity Pathway Analysis for human-mouse orthologues
Supplementary Table 1 from Paclitaxel Enhances Therapeutic Efficacy of the F8-IL2 Immunocytokine to EDA-Fibronectin–Positive Metastatic Human Melanoma Xenografts
Authors: Moschetta Michele , Pretto Francesca , Berndt Alexander , Galler Kerstin , Richter Petra , Bassi Andrea , Oliva Paolo , Micotti Edoardo , Valbusa Giovanni , Schwager Kathrin , Kaspar Manuela , Trachsel Eveline , Kosmehl Hartwig , Bani Maria Rosa , Neri Dario , Giavazzi Raffaella
Published: March 2023

PDF file - 73K, Lung colony formation in nude mice given F8-IL2 immunocytokine alone or in combination with paclitaxel
Supplementary Figures 1-3 from Paclitaxel Enhances Therapeutic Efficacy of the F8-IL2 Immunocytokine to EDA-Fibronectin–Positive Metastatic Human Melanoma Xenografts
Authors: Moschetta Michele , Pretto Francesca , Berndt Alexander , Galler Kerstin , Richter Petra , Bassi Andrea , Oliva Paolo , Micotti Edoardo , Valbusa Giovanni , Schwager Kathrin , Kaspar Manuela , Trachsel Eveline , Kosmehl Hartwig , Bani Maria Rosa , Neri Dario , Giavazzi Raffaella
Published: March 2023

PDF file - 319K
Supplementary Figures 1-8 from Genomic Profiling of Isolated Circulating Tumor Cells from Metastatic Breast Cancer Patients
Authors: Magbanua Mark Jesus M. , Sosa Eduardo V. , Roy Ritu , Eisenbud Lauren E. , Scott Janet H. , Olshen Adam , Pinkel Dan , Rugo Hope S. , Park John W.
Published: March 2023

PDF file - 965K, FIG S1: Distribution of MAD estimates across all 102 circulating tumor cell samples FIG S2: Visualization of IE/FACS-isolated cells via hematoxylin/eosin staining; FIG S3: Visualization of IE/FACS-isolated cells via fluorescence in-situ hybridization (FISH) analysis; FIG S4: aCGH analysis of spiked BT474 cells at the single cell level; FIG S5: aCGH analysis of spiked MCF7 cells; FIG S6: Study flow chart; FIG S7: Sorting replication in Patient #303; FIG S8: Comparison of circulating tumor cells and matched primary tumor
Supplementary Figure Legends 1-4 from PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines
Authors: Peng Weiyi , Liu Chengwen , Xu Chunyu , Lou Yanyan , Chen Jieqing , Yang Yan , Yagita Hideo , Overwijk Willem W. , Lizée Gregory , Radvanyi Laszlo , Hwu Patrick
Published: March 2023

PDF file - 57K
Supplementary Video 1 from The Melanoma‐Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion
Authors: Khaitan Divya , Dinger Marcel E. , Mazar Joseph , Crawford Joanna , Smith Martin A. , Mattick John S. , Perera Ranjan J.
Published: March 2023

Supplementary Video 1 from The Melanoma‐Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion
Supplementary Figures 1-5 from The Melanoma‐Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion
Authors: Khaitan Divya , Dinger Marcel E. , Mazar Joseph , Crawford Joanna , Smith Martin A. , Mattick John S. , Perera Ranjan J.
Published: March 2023

Supplementary Figures 1-5 from The Melanoma‐Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion
Supplementary Figure 4 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Authors: Chen Runqiang , Yang Qingkai , Lee Jiing-Dwan
Published: March 2023

PDF file - 146K
Supplementary Table 1 from Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth
Authors: Kang Moo Rim , Yang Glen , Place Robert F. , Charisse Klaus , Epstein-Barash Hila , Manoharan Muthiah , Li Long-Cheng
Published: March 2023

PDF file - 24K, Oligonucleotide sequences
Supplementary Methods from Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth
Authors: Kang Moo Rim , Yang Glen , Place Robert F. , Charisse Klaus , Epstein-Barash Hila , Manoharan Muthiah , Li Long-Cheng
Published: March 2023

PDF file - 104K
Supplementary Methods from Oncogenic NRAS, Required for Pathogenesis of Embryonic Rhabdomyosarcoma, Relies upon the HMGA2–IGF2BP2 Pathway
Authors: Li Zhizhong , Zhang Yunyu , Ramanujan Krishnan , Ma Yan , Kirsch David G. , Glass David J.
Published: March 2023

PDF file - 102K, Contains supplemental information regarding antibodies used, cell growth and apoptosis assays, a tissue expression profile, microarray analysis and statistics.
Supplementary Figures 1 - 5 from Oncogenic NRAS, Required for Pathogenesis of Embryonic Rhabdomyosarcoma, Relies upon the HMGA2–IGF2BP2 Pathway
Authors: Li Zhizhong , Zhang Yunyu , Ramanujan Krishnan , Ma Yan , Kirsch David G. , Glass David J.
Published: March 2023

PDF file - 396K, HMGA1 mRNA is ubiquitously expressed (S1); HMGA2 is indispensable for rhabdomyosarcoma growth in vitro (S2); HMGA2 is indispensable for rhabdomyosarcoma growth in vivo (S3); IGF2BP2 is an important target of HMGA2 in rhabdomyosarcoma (S4); HMGA2 modestly regulates E2F pathway in rhabdomyosarcoma (S5).
Supplementary Figure 4 from Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
Authors: Cipponi Arcadi , Mercier Marjorie , Seremet Teofila , Baurain Jean-François , Théate Ivan , van den Oord Joost , Stas Marguerite , Boon Thierry , Coulie Pierre G. , van Baren Nicolas
Published: March 2023

PDF file - 4.3MB, Immunohistological detection of the indicated antigens in adjacent cryosections of primary melanoma T33
Supplementary Figure 2 from Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
Authors: Cipponi Arcadi , Mercier Marjorie , Seremet Teofila , Baurain Jean-François , Théate Ivan , van den Oord Joost , Stas Marguerite , Boon Thierry , Coulie Pierre G. , van Baren Nicolas
Published: March 2023

PDF file - 797K, Positive and Negative controls for the immunohistological detection of the indicated antigens in adjacent cryosections of an inflammatory tonsil
Supplementary Figures 1-6 from Loss of SNAIL Regulated miR-128-2 on Chromosome 3p22.3 Targets Multiple Stem Cell Factors to Promote Transformation of Mammary Epithelial Cells
Authors: Qian PengXu , Banerjee Arindam , Wu Zheng-Sheng , Zhang Xiao , Wang Hong , Pandey Vijay , Zhang Wei-Jie , Lv Xue-Fei , Tan Sheng , Lobie Peter E. , Zhu Tao
Published: March 2023

PDF file - 1291K, FIGURE S1: Representative data of genomic real-time PCR screening for DNA copy numbers of aberrant microRNAs on human chromosome 3p in breast carcinoma and the correlation between expression levels of miR-128 and ARPP21; FIGURE S2: miR-128 depletion confers non-tumorigenic MCF-10A cells with a malignant phenotype in vitro; FIGURE S3: Forced expression of miR-128 alters the morphology and reduces migration and invasion of MCF-7 cells in vitro, whereas miR-128 depletion confers non-tumorigenic HBL-100 cells with a malignant phenotype in vitro; FIGURE S4: miR-128 depletion confers a malignant phenotype on non-tumorigenic MCF-10A cells in vivo and miR-128 represses the CD44+CD24 Neg/Low population in mammary carcinoma cells; FIGURE S5: Interactions between miR-128 and its binding targets; FIGURE S6: Luciferase assay for promoter activity
Supplementary Tables 1-5 from LIN28 Expression in Malignant Germ Cell Tumors Downregulates let-7 and Increases Oncogene Levels
Authors: Murray Matthew J. , Saini Harpreet K. , Siegler Charlotte A. , Hanning Jennifer E. , Barker Emily M. , van Dongen Stijn , Ward Dawn M. , Raby Katie L. , Groves Ian J. , Scarpini Cinzia G. , Pett Mark R. , Thornton Claire M. , Enright Anton J. , Nicholson James C. , Coleman Nicholas
Published: March 2023

PDF - 62K, Supplementary Table 1: Clinico-pathological data for sample set-3. Supplementary Table 2: Primers used for mRNA qRT-PCR. Supplementary Table 3: Expression of let-7 family microRNAs in pediatric malignant-GCTs. Supplementary Table 4: Let-7 mRNA targets identified in combined microarray analysis of pediatric and adult malignant-GCTs. Supplementary Table 5: The six let-7 mRNA targets selected following microarray and qRT-PCR analysis.
Supplementary Figure 3 from Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by Blimp-1–Dependent Repression of BMP-5
Authors: Romagnoli Mathilde , Belguise Karine , Yu Ziyang , Wang Xiaobo , Landesman-Bollag Esther , Seldin David C. , Chalbos Dany , Barillé-Nion Sophie , Jézéquel Pascal , Seldin Margaret L. , Sonenshein Gail E.
Published: March 2023

PDF file - 93K, TGFB1 and BLIMP1 are correlated in both ER+ and ER- breast cancer patients
Supplementary Figure 1 from Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by Blimp-1–Dependent Repression of BMP-5
Authors: Romagnoli Mathilde , Belguise Karine , Yu Ziyang , Wang Xiaobo , Landesman-Bollag Esther , Seldin David C. , Chalbos Dany , Barillé-Nion Sophie , Jézéquel Pascal , Seldin Margaret L. , Sonenshein Gail E.
Published: March 2023

PDF file - 167K, Blimp-1 is induced by TGF-beta1 and required for TGF-beta1-induced EMT signature in Hs578T breast cancer cells
Supplementary Figure 4 from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: March 2023

PDF file - 415K, Showing the effect of DCA (or YC-1) plus elesclomol on ROS production in several melanoma cell lines
Supplementary Figure 2 from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: March 2023

PDF file - 511K, Showing the impact of HIF-1α shRNA on mitochondria
Supplementary Figures 9 - 10 from MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells
Authors: Plummer Prue N. , Freeman Ruth , Taft Ryan J. , Vider Jelena , Sax Michael , Umer Brittany A. , Gao Dingcheng , Johns Christopher , Mattick John S. , Wilton Stephen D. , Ferro Vito , McMillan Nigel A.J. , Swarbrick Alexander , Mittal Vivek , Mellick Albert S.
Published: March 2023

PDF file, 321K, Supplementary Figure S9. ISH Analysis of Normal and Tumor Vasculature; and Murine Endothelial Cells In Vitro. Supplementary Figure S10. MiRNA Expression in Human Breast Tumor Endothelial Cells.
Supplementary Figure Legend from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: March 2023

PDF file - 43K
Supplementary Figure 5 from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: March 2023

PDF file - 2288K, Supplemental Figure 5: Aurk inhibitor blocks tumor growth in vivo.
Supplementary Table from C1GALT1 Enhances Proliferation of Hepatocellular Carcinoma Cells via Modulating MET Glycosylation and Dimerization
Authors: Wu Yao-Ming , Liu Chiung-Hui , Huang Miao-Juei , Lai Hong-Shiee , Lee Po-Huang , Hu Rey-Heng , Huang Min-Chuan
Published: March 2023

PDF file, 130K, Correlation of C1GALT1 expression with clinicopathologic features in HCC tissue microarray.
Supplementary Figure 3 from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: March 2023

PDF file - 2421K, Supplemental Figure 3: Aurk inhibitor cooperates with SHH antagonist and chemotherapeutic agents.
Supplementary Figure 1 from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: March 2023

PDF file - 3091K, Supplemental Figure 1: Cell cycle progression occurs more rapidly in CD15+ cells than in CD15- cells.
Supplementary Figure S3 from Extracellular DNA in Pancreatic Cancer Promotes Cell Invasion and Metastasis
Authors: Wen Fushi , Shen Alex , Choi Andrew , Gerner Eugene W. , Shi Jiaqi
Published: March 2023

PDF file - 1673K, DNase I does not degrade integrin beta 1
Supplementary Tables from Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
Authors: Arendt Lisa M. , McCready Jessica , Keller Patricia J. , Baker Dana D. , Naber Stephen P. , Seewaldt Victoria , Kuperwasser Charlotte
Published: March 2023

PDF file, 65K, Primers for quantitative Real-Time PCR (S1); Obesity-like stromal cells shorten the latency and increase the incidence of tumor development (S2).
Supplementary Figure 7 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: March 2023

PDF file - 1205K, Figure S7. Treatment of HER2 amplified cell lines with LJM716/ trastuzumab combinations is synergistic in a subset of cell lines.
Supplementary Figure 6 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: March 2023

PDF file - 416K, Figure S6. Trastuzumab/LJM716 combination inhibits 3D spheroid growth of breast cancer cell lines more effectively than trastuzumab/pertuzumab combination.
Supplementary Figure 5 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: March 2023

PDF file - 237K, Figure S5. Combination treatment consisting of trastuzumab+LJM716 or Cetuximab+LJM716 is well tolerated.
Supplementary Figure 1 from Adenomatous Polyps Are Driven by Microbe-Instigated Focal Inflammation and Are Controlled by IL-10–Producing T Cells
Authors: Dennis Kristen L. , Wang Yunwei , Blatner Nichole R. , Wang Shuya , Saadalla Abdulrahman , Trudeau Erin , Roers Axel , Weaver Casey T. , Lee James J. , Gilbert Jack A. , Chang Eugene B. , Khazaie Khashayarsha
Published: March 2023

PDF file, 1583K, Thy1.1-biotin isotype control staining of gut tissues.
Supplementary Table 2 from NSD2 Is Recruited through Its PHD Domain to Oncogenic Gene Loci to Drive Multiple Myeloma
Authors: Huang Zheng , Wu Haiping , Chuai Shannon , Xu Fiona , Yan Feng , Englund Nathan , Wang Zhaofu , Zhang Hailong , Fang Ming , Wang Youzhen , Gu Justin , Zhang Man , Yang Teddy , Zhao Kehao , Yu Yanyan , Dai Jingquan , Yi Wei , Zhou Shaolian , Li Qian , Wu Jing , Liu Jun , Wu Xu , Chan Homan , Lu Chris , Atadja Peter , Li En , Wang Yan , Hu Min
Published: March 2023

XLSX file, 863K, Lists of differentially expressed genes (DEGs) from comparisons of PAR_TKO and active_inactive groups and overlapping DEGs (p<0.05).
Supplementary Table 2 from Proteomic and Lipidomic Signatures of Lipid Metabolism in NASH-Associated Hepatocellular Carcinoma
Authors: Muir Kyle , Hazim Antonious , He Ying , Peyressatre Marion , Kim Do-Young , Song Xiaoling , Beretta Laura
Published: March 2023

Supplementary Table 2�- PDF file 50K, Primer sequences used for quantitative PCR
Supplementary Figures S1-S4 from miR-214 Coordinates Melanoma Progression by Upregulating ALCAM through TFAP2 and miR-148b Downmodulation
Authors: Penna Elisa , Orso Francesca , Cimino Daniela , Vercellino Irene , Grassi Elena , Quaglino Elena , Turco Emilia , Taverna Daniela
Published: March 2023

Supplementary Figures S1-S4 - PDF file 482K, miR-214, miR-148b and ALCAM expression modulations (S1); ALCAM is upregulated by miR-214 and controls cell movement but not proliferation (S2); ALCAM and miR-148b regulations (S3); ALCAM, miR-214, miR-148b and TFAP2 expression in human melanoma samples (S4)
Sweave Document from Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
Authors: Tyner Jeffrey W. , Yang Wayne F. , Bankhead Armand , Fan Guang , Fletcher Luke B. , Bryant Jade , Glover Jason M. , Chang Bill H. , Spurgeon Stephen E. , Fleming William H. , Kovacsovics Tibor , Gotlib Jason R. , Oh Stephen T. , Deininger Michael W. , Zwaan Christian Michel , Den Boer Monique L. , van den Heuvel-Eibrink Marry M. , O'Hare Thomas , Druker Brian J. , Loriaux Marc M.
Published: March 2023

PDF file - 378K
Supplementary Figure 2 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer
Authors: Jansen Maurice P.H.M. , Knijnenburg Theo , Reijm Esther A. , Simon Iris , Kerkhoven Ron , Droog Marjolein , Velds Arno , van Laere Steven , Dirix Luc , Alexi Xanthippi , Foekens John A. , Wessels Lodewyk , Linn Sabine C. , Berns Els M.J.J. , Zwart Wilbert
Published: March 2023

PDF file - 100K, Supplementary Figure S2 Overlap of peaks from the same ChIP-seq condition between tumors.
Supplementary Materials and Methods from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Authors: Zhang Lei , Pickard Karen , Jenei Veronika , Bullock Marc D. , Bruce Amanda , Mitter Richard , Kelly Gavin , Paraskeva Christos , Strefford John , Primrose John , Thomas Gareth J. , Packham Graham , Mirnezami Alex H.
Published: March 2023

PDF file, 134K.
Supplementary Figure 1 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Authors: Zhang Lei , Pickard Karen , Jenei Veronika , Bullock Marc D. , Bruce Amanda , Mitter Richard , Kelly Gavin , Paraskeva Christos , Strefford John , Primrose John , Thomas Gareth J. , Packham Graham , Mirnezami Alex H.
Published: March 2023

PDF file, 4936K, MiRNA profiling concordance and summary DAVID data.
Supplementary Figure Legends 1-6 from Constitutive HER2 Signaling Promotes Breast Cancer Metastasis through Cellular Senescence
Authors: Angelini Pier Davide , Fluck Mariano F. Zacarias , Pedersen Kim , Parra-Palau Josep Lluís , Guiu Marc , Bernadó Morales Cristina , Vicario Rocio , Luque-García Antonio , Navalpotro Nerea Peiró , Giralt Jordi , Canals Francesc , Gomis Roger R. , Tabernero Josep , Baselga José , Villanueva Josep , Arribas Joaquín
Published: March 2023

PDF file - 76K
Supplementary Figure 3 from Neuropilin-2 Promotes Extravasation and Metastasis by Interacting with Endothelial α5 Integrin
Authors: Cao Ying , Hoeppner Luke H. , Bach Steven , E Guangqi , Guo Yan , Wang Enfeng , Wu Jianmin , Cowley Mark J. , Chang David K. , Waddell Nicola , Grimmond Sean M. , Biankin Andrew V. , Daly Roger J. , Zhang Xiaohui , Mukhopadhyay Debabrata
Published: March 2023

PDF file - 104K, Supplemental Fig.3. (A). NRP-2 knockdown in 786-O didn't significantly change cell proliferation, migration and invasion. (B). NRP-2 knockdown in 786-O and A-498 did not significantly change p-AKT, p-ERK, p-p38, p53 and MDM-2 levels.
Supplementary Methods, Figure Legends, Tables 1 - 3 from Nkx2-8 Downregulation Promotes Angiogenesis and Activates NF-κB in Esophageal Cancer
Authors: Lin Chuyong , Song Libing , Gong Hui , Liu Aibin , Lin Xi , Wu Jueheng , Li Mengfeng , Li Jun
Published: March 2023

PDF file - 125K, Supplementary Table 1. Clinicopathological characteristics of studied patients and expression of Nkx2-8 in ESCC; Supplementary Table 2. Correlation between the clinicopathological features and expression of Nkx2-8; Supplementary Table 3. Univariate and multivariate analysis of different prognostic parameters in patients with ESCC by Cox-regression analysis.
Supplementary Figure 4 from miR145 Targets the SOX9/ADAM17 Axis to Inhibit Tumor-Initiating Cells and IL-6–Mediated Paracrine Effects in Head and Neck Cancer
Authors: Yu Cheng-Chia , Tsai Lo-Lin , Wang Mong-Lien , Yu Chuan-Hang , Lo Wen-Liang , Chang Yun-Ching , Chiou Guang-Yuh , Chou Ming-Yung , Chiou Shih-Hwa
Published: March 2023

PDF file - 254K, Suppl. Fig. 4. Curcumin suppresses the migratory capability of ALDH+CD44+ HNC cells through the miR145-SOX9/ADAM17 pathway
Supplementary Figure 2 from Nitric Oxide Production Upregulates Wnt/β-Catenin Signaling by Inhibiting Dickkopf-1
Authors: Du Qiang , Zhang Xinglu , Liu Quan , Zhang Xianghong , Bartels Christian E. , Geller David A.
Published: March 2023

PDF file - 69K, iNOS induced expressions of Wnt signaling pathway related-genes. A, A pair of SW480 cell lines was generated that stably overexpressed hiNOS (SW480-iNOS), compared with its control cell line (SW480-GFP), which were used for the SuperArray analysis. Expressions of Wnt signaling pathway related-genes (114 genes) in SW480-iNOS compared with SW480-GFP is shown. Cells were incubated for 24 hours and total RNA was isolated for the SuperArray analysis. B, In SuperArray analysis, the red + spots indicate a gene expression ratio >1.5 of SW480-iNOS / SW480-GFP cells, whereas the green + sign indicates a ratio < 1.5 of SW480-iNOS / SW480-GFP cells.
Supplementary Figures from Rapid Induction of Lung Adenocarcinoma by Fibroblast Growth Factor 9 Signaling through FGF Receptor 3
Authors: Yin Yongjun , Betsuyaku Tomoko , Garbow Joel R. , Miao Jinbai , Govindan Ramaswamy , Ornitz David M.
Published: March 2023

PDF file, 3363K, Expression of eGFP and Fgf9 following doxycycline induction for four days (S1); FGF9 promotes proliferation of cells in the bronchioalveolar duct junction (S2); Co-expression of FGFR3 and Sca-1 in the bronchioalveolar duct junction following induction of FGF9 (S3).
Supplementary Methods, Figure Legends, Tables 1 - 2 from miR-186 Downregulation Correlates with Poor Survival in Lung Adenocarcinoma, Where It Interferes with Cell-Cycle Regulation
Authors: Cai Junchao , Wu Jueheng , Zhang Huizhong , Fang Lishan , Huang Yongbo , Yang Yi , Zhu Xun , Li Rong , Li Mengfeng
Published: March 2023

PDF file - 182K, Clinicopathologic characteristics of patients enrolled for sample examination and expression of miR-186 in lung cancer, Correlation between the clinical pathologic features and expression of miR-186 levels
Supplementary Figure 1 from miR-186 Downregulation Correlates with Poor Survival in Lung Adenocarcinoma, Where It Interferes with Cell-Cycle Regulation
Authors: Cai Junchao , Wu Jueheng , Zhang Huizhong , Fang Lishan , Huang Yongbo , Yang Yi , Zhu Xun , Li Rong , Li Mengfeng
Published: March 2023

PDF file - 23K, Real-time analysis of miR-186 expression in A549 and SK-MES-1 cells transduced with control vector or miR-186
Supplementary Tables 1 - 2 from Hedgehog Signaling Alters Reliance on EGF Receptor Signaling and Mediates Anti-EGFR Therapeutic Resistance in Head and Neck Cancer
Authors: Keysar Stephen B. , Le Phuong N. , Anderson Ryan T. , Morton J. Jason , Bowles Daniel W. , Paylor Jeramiah J. , Vogler Brian W. , Thorburn Jackie , Fernandez Pamela , Glogowska Magdalena J. , Takimoto Sarah M. , Sehrt Daniel B. , Gan Gregory N. , Eagles-Soukup Justin R. , Serracino Hilary , Hirsch Fred R. , Lucia M. Scott , Thorburn Andrew , Song John I. , Wang Xiao-Jing , Jimeno Antonio
Published: March 2023

PDF file - 29K, EGFR dependent EMT quantified as percent Vimentin-positive cells in culture (S1); Combination therapy delays or blocks tumor re-growth in sensitive xenografts (S2).
Supplementary Figures 1 - 8 from Connective Tissue Growth Factor Activates Pluripotency Genes and Mesenchymal–Epithelial Transition in Head and Neck Cancer Cells
Authors: Chang Cheng-Chi , Hsu Wen-Hao , Wang Chen-Chien , Chou Chun-Hung , Kuo Mark Yen-Ping , Lin Been-Ren , Chen Szu-Ta , Tai Shyh-Kuan , Kuo Min-Liang , Yang Muh-Hwa
Published: March 2023

PDF file - 541K, Expression of CTGF among HNSCC cell lines, and CTGF does not have significant impact on HNSCC cells proliferation (S1); CTGF enriches stem-like population of SAS cells (S2); CTGF promotes stem-like properties of FaDu cells (S3); Exogenous CTGF promotes stem-like properties of HNSCC cells (S4); The impact of CTGF on pluripotency genes expression in HNSCC cells (S5); CTGF induces the expression of pluripotency genes in a dose and time-dependent manner (S6); c-Jun and ESR1 are critical for CTGF-induced pluripotency genes expression (S7); CTGF activates POU5F1/NANOG/SOX2 transcription through ESR1 (S8).
Supplementary Movie 2 from Microtubule-Associated Histone Deacetylase 6 Supports the Calcium Store Sensor STIM1 in Mediating Malignant Cell Behaviors
Authors: Chen Ying-Ting , Chen Yih-Fung , Chiu Wen-Tai , Liu Kuan-Yu , Liu Yu-Lin , Chang Jang-Yang , Chang Hsien-Chang , Shen Meng-Ru
Published: March 2023

AVI file - 2482K
Supplementary Figure 5 from Microtubule-Associated Histone Deacetylase 6 Supports the Calcium Store Sensor STIM1 in Mediating Malignant Cell Behaviors
Authors: Chen Ying-Ting , Chen Yih-Fung , Chiu Wen-Tai , Liu Kuan-Yu , Liu Yu-Lin , Chang Jang-Yang , Chang Hsien-Chang , Shen Meng-Ru
Published: March 2023

PDF file - 1456K, HDAC6 is involved in STIM1 trafficking, proliferation and migration of cervical cancer cells.
Supplementary Figures 1 - 6 from Tumor MMP-1 Activates Endothelial PAR1 to Facilitate Vascular Intravasation and Metastatic Dissemination
Authors: Juncker-Jensen Anna , Deryugina Elena I. , Rimann Ivo , Zajac Ewa , Kupriyanova Tatyana A. , Engelholm Lars H. , Quigley James P.
Published: March 2023

PDF file - 199K, Effects of MMP-1 silencing on HEp3-hi/diss cell proliferation in 2D and 3D culture conditions (S1); HEp3-hi/diss tissue colonization does not depend on MMP-1 expression (S2); Effects of MMP-1 downregulation on HEp3-hi/diss cell adhesion and invasion (S3); Inhibition of vascular permeability in HEp3-hi/diss microtumors by the PAR1 antagonist RWJ 56110 (S4); Inhibition of HEp3-hi/diss intravasation by a PAR1 antagonist (S5); MMP-1 produced by the human HNSCC Detroit 562 concomitantly regulates vascular permeability and intravasation (S6).
Supplementary Figure 3 from miRNA-95 Mediates Radioresistance in Tumors by Targeting the Sphingolipid Phosphatase SGPP1
Authors: Huang Xiaoyong , Taeb Samira , Jahangiri Sahar , Emmenegger Urban , Tran Elisa , Bruce Jeff , Mesci Aruz , Korpela Elina , Vesprini Danny , Wong C. Shun , Bristow Robert G. , Liu Fei-Fei , Liu Stanley K.
Published: March 2023

PDF file - 4059K, SGPP1 transcript levels in DU145 cells transfected with miR-95 mimic.
Supplementary Figure 3 from G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic
Authors: Hsu Danielle M. , Agarwal Saurabh , Benham Ashley , Coarfa Cristian , Trahan Denae N. , Chen Zaowen , Stowers Paris N. , Courtney Amy N. , Lakoma Anna , Barbieri Eveline , Metelitsa Leonid S. , Gunaratne Preethi , Kim Eugene S. , Shohet Jason M.
Published: March 2023

PDF file - 67K, Model for CD114+ and CD114- cells in neural crest development.
Supplementary Figure 6 from Nm23-H1 Binds to Gelsolin and Inactivates Its Actin-Severing Capacity to Promote Tumor Cell Motility and Metastasis
Authors: Marino Natascia , Marshall Jean-Claude , Collins Joshua W. , Zhou Ming , Qian Yongzhen , Veenstra Timothy , Steeg Patricia S.
Published: March 2023

PDF file, 189K, Gelsolin effect on the cell motility of 4T1 and MDA-MB-231T cells is motility factor-dependent.
Supplementary Table 2 from Mutationally Activated PIK3CAH1047R Cooperates with BRAFV600E to Promote Lung Cancer Progression
Authors: Trejo Christy L. , Green Shon , Marsh Victoria , Collisson Eric A. , Iezza Gioia , Phillips Wayne A. , McMahon Martin
Published: March 2023

PDF file, 41K, Percentages of BRAFV600E/PIK3CAH1047R/TP53null cells found to be in different stages of the cell division cycle following pathway-targeted pharmacological inhibition of cell signaling.
Supplementary Figure 1 from Mutationally Activated PIK3CAH1047R Cooperates with BRAFV600E to Promote Lung Cancer Progression
Authors: Trejo Christy L. , Green Shon , Marsh Victoria , Collisson Eric A. , Iezza Gioia , Phillips Wayne A. , McMahon Martin
Published: March 2023

PDF file, 106K, Pharmacological inhibition of AKT does not inhibit BRAFV600E-initiated lung tumorigenesis.
Figure S1 from Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8
Authors: Hartman Zachary C. , Poage Graham M. , den Hollander Petra , Tsimelzon Anna , Hill Jamal , Panupinthu Nattapon , Zhang Yun , Mazumdar Abhijit , Hilsenbeck Susan G. , Mills Gordon B. , Brown Powel H.
Published: March 2023

Figure S1 - PDF file 76K, Flow chart outlining the analyses and selection criteria utilized for the identification of inflammatory genes with differential expression in both patient and cell line datasets
Supplementary Figure 1 from Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors
Authors: Chakrabarty Anindita , Bhola Neil E. , Sutton Cammie , Ghosh Ritwik , Kuba María Gabriela , Dave Bhuvanesh , Chang Jenny C. , Arteaga Carlos L.
Published: March 2023

PDF file - 125K, Inhibition of trastuzumab-resistant cells by RNAi of p110 alpha and beta
Supplementary Methods from Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma
Authors: Natarajan Sivaraman , Li Yaochen , Miller Emily E. , Shih David J. , Taylor Michael D. , Stearns Timothy M. , Bronson Roderick T. , Ackerman Susan L. , Yoon Jeong K. , Yun Kyuson
Published: March 2023

PDF file - 79K
Supplementary Figure Legend from Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma
Authors: Natarajan Sivaraman , Li Yaochen , Miller Emily E. , Shih David J. , Taylor Michael D. , Stearns Timothy M. , Bronson Roderick T. , Ackerman Susan L. , Yoon Jeong K. , Yun Kyuson
Published: March 2023

PDF file - 89K
Supplementary Methods from ALX1 Induces Snail Expression to Promote Epithelial-to-Mesenchymal Transition and Invasion of Ovarian Cancer Cells
Authors: Yuan Hong , Kajiyama Hiroaki , Ito Satoko , Yoshikawa Nobuhisa , Hyodo Toshinori , Asano Eri , Hasegawa Hitoki , Maeda Masao , Shibata Kiyosumi , Hamaguchi Michinari , Kikkawa Fumitaka , Senga Takeshi
Published: March 2023

PDF file - 46K, Includes information regarding plasmids, In situ hybridization, Immunofluorescence and immunoblot analysis, as well as RT-PCR
Supplementary Figure 3 from Convergence of the ZMIZ1 and NOTCH1 Pathways at C-MYC in Acute T Lymphoblastic Leukemias
Authors: Rakowski Lesley A. , Garagiola Derek D. , Li Choi M. , Decker Margaret , Caruso Sarah , Jones Morgan , Kuick Rork , Cierpicki Tomasz , Maillard Ivan , Chiang Mark Y.
Published: March 2023

PDF file - 5445K, Figure S3. ZMIZ1 RNA and protein levels were reduced by ZMIZ1-targeted shRNA.
Supplementary Figure 6 from DKK2 Mediates Osteolysis, Invasiveness, and Metastatic Spread in Ewing Sarcoma
Authors: Hauer Kristina , Calzada-Wack Julia , Steiger Katja , Grunewald Thomas G.P. , Baumhoer Daniel , Plehm Stephanie , Buch Thorsten , da Costa Olivia Prazeres , Esposito Irene , Burdach Stefan , Richter Günther H.S.
Published: March 2023

PDF file - 4007KB, DKK2 seems to be a Wnt agonist in ES
Supplementary Figure 1 from DKK2 Mediates Osteolysis, Invasiveness, and Metastatic Spread in Ewing Sarcoma
Authors: Hauer Kristina , Calzada-Wack Julia , Steiger Katja , Grunewald Thomas G.P. , Baumhoer Daniel , Plehm Stephanie , Buch Thorsten , da Costa Olivia Prazeres , Esposito Irene , Burdach Stefan , Richter Günther H.S.
Published: March 2023

PDF file - 2784KB, DKK2 expression in different small-round-blue cell tumors
Supplementary Table 1 from Oncogenic Protein MTBP Interacts with MYC to Promote Tumorigenesis
Authors: Grieb Brian C. , Gramling Mark W. , Arrate Maria Pia , Chen Xi , Beauparlant Stephen L. , Haines Dale S. , Xiao Hua , Eischen Christine M.
Published: March 2023

PDF file - 91KB, Supplemental Table 1 shows the frequency of MTBP and MYC amplification and co-amplification in 20 human cancers.
Supplementary Material 9 from Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications
Authors: Grosse Laurent , Pâquet Sophie , Caron Patrick , Fazli Ladan , Rennie Paul S. , Bélanger Alain , Barbier Olivier
Published: March 2023

PDF file - 23K, Supplementary material 9: Doxycycline activation of AR shRNA modulates the mRNA levels of the receptor (A) and its negative (ABCG1, B) and positive (PSA, C) target genes.
Data Supplement from Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer
Authors: Endesfelder David , Burrell Rebecca A. , Kanu Nnennaya , McGranahan Nicholas , Howell Mike , Parker Peter J. , Downward Julian , Swanton Charles , Kschischo Maik
Published: March 2023

Supplementary Figure S2. Expression of core regulator modules with increasing wGII score. Tumour samples were grouped into four groups of increasing wGII score (columns). The heatmap displays the expression of each core regulator module (rows) in the different wGII groups. Module expression was quantified by the mean expression over all module genes and all samples in the given wGII quartile.
Supplementary Material 1 from Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications
Authors: Grosse Laurent , Pâquet Sophie , Caron Patrick , Fazli Ladan , Rennie Paul S. , Bélanger Alain , Barbier Olivier
Published: March 2023

PDF file - 20K, Supplementary material 1: Age, clinical stage of the disease (cT), tumor grade (Gleason score) and serum PSA from PCa sample donors.
Supplementary Figure 1 from Cyclin D1 Integrates Estrogen-Mediated DNA Damage Repair Signaling
Authors: Li Zhiping , Chen Ke , Jiao Xuanmao , Wang Chenguang , Willmarth Nicole E. , Casimiro Mathew C. , Li Weihua , Ju Xiaoming , Kim Sung Hoon , Lisanti Michael P. , Katzenellenbogen John A. , Pestell Richard G.
Published: March 2023

PDF file - 15KB, Endogenous cyclin D1 mediates both E2 and EDC-induced yH2AX in MCF-7 cells.
Supplementary Figure S7 from mTOR Complex 2 Is Involved in Regulation of Cbl-Dependent c-FLIP Degradation and Sensitivity of TRAIL-Induced Apoptosis
Authors: Zhao Liqun , Yue Ping , Khuri Fadlo R. , Sun Shi-Yong
Published: March 2023

Supplementary Figure S7 PDF file - 106K, Enforced activation of Akt does not impair the ability of PP242 to reduce FLIPS levels
Supplementary Figure S1 from mTOR Complex 2 Is Involved in Regulation of Cbl-Dependent c-FLIP Degradation and Sensitivity of TRAIL-Induced Apoptosis
Authors: Zhao Liqun , Yue Ping , Khuri Fadlo R. , Sun Shi-Yong
Published: March 2023

Supplementary Figure S1 PDF file - 69K,Combination Indexes (CIs) for interaction between PP242 and TRAIL in NSCLC cells
Supplementary Figure Legends from Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer
Authors: Chatterjee Sampurna , Wieczorek Caroline , Schöttle Jakob , Siobal Maike , Hinze Yvonne , Franz Thomas , Florin Alexandra , Adamczak Joanna , Heukamp Lukas C. , Neumaier Bernd , Ullrich Roland T.
Published: March 2023

PDF file - 66KB
Supplementary Figure 4 from Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer
Authors: Chatterjee Sampurna , Wieczorek Caroline , Schöttle Jakob , Siobal Maike , Hinze Yvonne , Franz Thomas , Florin Alexandra , Adamczak Joanna , Heukamp Lukas C. , Neumaier Bernd , Ullrich Roland T.
Published: March 2023

PDF file - 1341KB, Pericyte coverage and tumor cell proliferation.
Supplementary Video 6 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: March 2023

AVI file - 1297KB, Representative 3D RENDERING E7 EETE.
Supplementary Figure Legend from Mixed Lineage Kinase MLK4 Is Activated in Colorectal Cancers Where It Synergistically Cooperates with Activated RAS Signaling in Driving Tumorigenesis
Authors: Martini Miriam , Russo Mariangela , Lamba Simona , Vitiello Elisa , Crowley Emily Hannah , Sassi Francesco , Romanelli Davide , Frattini Milo , Marchetti Antonio , Bardelli Alberto
Published: March 2023

PDF file - 98K
Supplementary Figure 4 from Mixed Lineage Kinase MLK4 Is Activated in Colorectal Cancers Where It Synergistically Cooperates with Activated RAS Signaling in Driving Tumorigenesis
Authors: Martini Miriam , Russo Mariangela , Lamba Simona , Vitiello Elisa , Crowley Emily Hannah , Sassi Francesco , Romanelli Davide , Frattini Milo , Marchetti Antonio , Bardelli Alberto
Published: March 2023

PDF file - 161K, Ctrl and MLK4 knock down DLD were seeded and allowed to grow for the indicated times in flasks with ultra-low attachment surface to prevent cell adhesion. Cells were harvested and protein lysates were subjected to western blotting with the indicated antibodies.
Supplementary Figure 2 from TGF-β Mediates Homing of Bone Marrow–Derived Human Mesenchymal Stem Cells to Glioma Stem Cells
Authors: Shinojima Naoki , Hossain Anwar , Takezaki Tatsuya , Fueyo Juan , Gumin Joy , Gao Feng , Nwajei Felix , Marini Frank C. , Andreeff Michael , Kuratsu Jun-Ichi , Lang Frederick F.
Published: March 2023

PDF file - 1271K, Proliferation effects of knocking down TGFβRII or CD105 in BM-hMSCs.