bluuebunny/crossref_metadata_2025 huggingface dataset:
Incentivos electorales para combatir el abstencionismo en la democracia pastusa: uso de las redes sociales y comunicación digital
Authors: Paredes Mora Valentina Esther
Published: August 2023

Las acciones humanas jamás son perfectas; sin embargo, y sin discusiones, la democracia enmarcada en todas sus variables, es un concepto que históricamente se ha dotado de importancia social y política, encaminada a la construcción de formas de gobierno con equilibrio entre el ciudadano y quien lo representa, método dentro del cual ese mismo ciudadano tiene un papel determinante, pues elige, vota, escoge y enajena el poder a un tercero, en beneficio de sus intereses.
Estudio de factibilidad para el montaje de una planta productora y comercializadora de amaranto en el municipio de Consacá, departamento de Nariño
Authors: Gelpud Criollo Diana Marcela , Gómez Macías Nathaly Valentina , Jaimes Urbano Jelsyn Julieth
Published: August 2023

El presente artículo es resultado de la investigación titulada Estudio de factibilidad para el montaje de una planta productora y comercializadora de amaranto en el municipio de Consacá, departamento de Nariño, para lo cual fue fundamental el desarrollo de cinco objetivos específicos que abarcaron la elaboración de un estudio de mercado, estudio técnico, estudio administrativo, estudio financiero y, finalmente, análisis del impacto socio ambiental, fundamentado en un tipo de investigación descriptiva, paradigma cuantitativo, enfoque empírico analítico y método deductivo. Los instrumentos de recolección de información fueron encuestas dirigidas a consumidores y a canales de distribución de la ciudad de Pasto. Los resultados obtenidos dan a entender, primero, que la mayoría de personas no conoce el amaranto; segundo, los consumidores más habituales son los estudiantes universitarios entre 18 y 25 años, a quienes les interesa conocer más sobre el producto y sus propiedades, cuidar su salud y consumir alimentos que proporcionen un gran valor nutricional. Finalmente, se puede decir que el amaranto es un alimento de gran valor nutritivo, ya que proporciona excelentes beneficios a la salud, logrando adaptarse a cualquier tipo de consumidor, siendo un nuevo producto alimenticio para ser incluido en la dieta de la población nariñense.
Konstytucyjne prawo do zabezpieczenia społecznego w razie pozostawania bez pracy (zarys problematyki)
Authors: Kosut Anna
Published: August 2023

Konstytucja Rzeczypospolitej Polskiej z 1997 r. przewiduje prawo obywateli do zabezpieczenia społecznego w razie wystąpienia określonych w art. 67 ryzyk socjalnych. Jednym z nich jest pozostawanie bez pracy nie z własnej woli, przy braku innych środków utrzymania. Należy uznać, że w ten sposób określone zostało w ustawie zasadniczej ryzyko bezrobocia. Ochrona przed jego skutkami realizowana jest formami przewidzianymi przez ustawodawcę, przede wszystkim poprzez zasiłek dla bezrobotnych. W opracowaniu przedstawiono przesłanki, których spełnienie przesądza o możliwości korzystania z prawa do zabezpieczenia społecznego w razie pozostawania bez pracy. Odniesiono się także do kwestii charakteru prawnego zasiłku dla bezrobotnych. Wskazano również na związek między sposobem realizacji prawa do zabezpieczenia społecznego a bezpieczeństwem socjalnym obywateli.
Z problematyki łańcuszkowego podżegania
Authors: Kulik Marek
Published: August 2023

Artykuł dotyczy dopuszczalności przyjęcia konstrukcji tzw. łańcuszkowego podżegania, czyli sytuacji, w której podżegacz nakłania inną osobę nie do popełnienia czynu w postać sprawstwa, lecz w postaci dalszego podżegania. Autor uważa tę konstrukcję za dopuszczalną i uzasadnia to. Nadto analizuje kilka podstawowych zagadnień szczegółowych wiążących się z łańcuszkowym podżeganiem.
OCCURRENCE OF IMMATURE SHARKS IN ARTISANAL FISHERIES OF THE SOUTHERN GULF OF MEXICO
Authors: Pérez-Jiménez Juan Carlos , Mendoza-Carranza Manuel
Published: August 2023

A common feature of Mexican artisanal fisheries is the high proportion of immature sharks in catches. Immature sharks have been historically caught in the southern Gulf of Mexico; however, there is a lack of catch rate estimates. Fishery-dependent sampling in the states of Tabasco (2007-2010 and 2012-2014) and Campeche (2011-2014) was conducted to estimate catch rates of immature sharks of large shark species (species reaching > 150 cm of total length). The catch rate of the 12 recorded species was < 1 shark/fishing day. Immature individuals accounted for a high percentage of the sharks caught in Tabasco (94.5%) and Campeche (90%). We suggest the coast of both states is a juvenile shark habitat for the 12 species. Sharks with predominantly coastal habitats are probably more vulnerable to anthropogenic impacts in the study area, including artisanal fisheries, the oil industry, and coastal development.Keywords: shark nurseries, juvenile shark habitat, fishery management, Campeche Bank.
Anti-VEGF-therapy for pseudoxanthoma elasticum (case reports)
Authors:   Orenburg Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Orenburg, Russian Federation, Chuprov A.D. , Kim S.M. ,   Orenburg Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Orenburg, Russian Federation, Pidodniy E.A. ,   Orenburg Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Orenburg, Russian Federation, Iserkepova A.M. ,   Orenburg Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Orenburg, Russian Federation
Published: August 2023

Pseudoxanthoma elasticum (PXE), also known as Gröenblad-Strandberg syndrome, is a rare autosomal recessive disease affecting the skin, eyes, gastrointestinal tract, and cardiovascular system. The disease is caused by a defect in ABCC 6 (adenosine triphosphate-binding cassette, subfamily C, member 6) transporter involved in the homeostasis of serum pyrophosphate, the key inhibitor of ectopic calcification. Dysfunction or lack of ABCC 6 leads to a decrease in serum pyrophosphate levels and, as a result, ectopic calcification of soft connective tissue. Skin lesions in PXE are flat yellowish xanthomatous nodules of various shapes and sizes. The leading signs of eye disorder are angioid streaks and choroidal neovascularization (CNV). Progressive destruction of Bruch's membrane favors CNV, whereas macular neovascularization is the key reason for a reduction in central vision in PXE. Intravitreal injection of anti-VEGF medications is a promising treatment for CNV due to angioid bands. Ranibizumab is approved for CNV of various origins, including CNV due to angioid streaks. This paper addresses clinical observations illustrating the efficacy of anti-VEGF therapy for pseudoxanthoma elasticum. KEYWORDS: Gröenblad-Strandberg syndrome, angioid streaks, choroidal neovascularization, pseudoxanthoma elasticum, VEGF inhibitors. FOR CITATION: Chuprov A.D., Kim S.M., Pidodniy E.A., Iserkepova A.M. Anti-VEGF-therapy for pseudoxanthoma elasticum (case reports). Russian Journal of Clinical Ophthalmology. 2023;23(3):157–163 (in Russ.). DOI: 10.32364/2311-7729-2023-23-3-8.
LENGTH-WEIGHT RELATIONSHIPS OF THREE FRESHWATER MUSSEL SPECIES FROM THE AMAZON (UNIONIDA, HYRIIDAE)
Authors: Barros Mara Rubia Ferreira , Abreu Valdo Sena , Quaresma Luciana Margalho , Chagas Rafael Anaisce das , Herrmann Marko , Amado Lilian Lund , Andrade Marcelo Costa
Published: August 2023

Length-weight relationships of three freshwater mussel species (Hyriidae), Eastern Amazon: the length-weight relationships allow important biological estimates for the fisheries management of species. Through this relationship, it is possible to estimate the weight of the individuals by their lengths, from which the biomass of the studied population can be determined. In addition, it gathers important data to assess the ecological patterns of different populations. The aim of this study was to analyze the length-weight relationships and their respective meat yields of three species of freshwater mussels: Castalia ambigua, Triplodon corrugatus and Paxyodon syrmatophorus from Capim River Bay, Pará, Brazil. For this, the total length, visceral weight, and total weight of 1,057 individuals were determined. All three relationships were considered strong, with determination coefficients greater than 0.9. The species C. ambigua showed negative allometric growth, while the other species P. syrmatophorus and T. corrugatus showed isometric growth. The species with the highest meat yield was P. syrmatophorus with 14.8%. The study presents the first parameter record of weight-length relationships for these three freshwater mussel species.
ASSESSMENT OF INDOOR SECOND-HAND CIGARETTE SMOKE ON THE RESPIRATORY MECHANICS AND PREVENTIVE BENEFITS OF EUCALYPTOL: A MURINE MODEL
Authors: Fernandes Neto Etevaldo Deves , Gondim Fladimir de Lima , Moura Marcelle Ferreira , Ferreira Ruth Mesquita , Andrade Leidianne Costa da Silva , Pimenta Antônia Torres Ávila , Serra Daniel Silveira , Cavalcante Francisco Sales Ávila
Published: August 2023

Second-hand smokers, in various settings such as recreational areas, schools, workplaces, homes and other enclosed public spaces also experience the detrimental effects of exposure to cigarette smoke (CS). Out of the 8 million deaths attributed to smoking, 1.2 million are a result of non-smokers being exposed to second-hand smoke. As a preventive strategy to these damages, Eucalyptol has been shown to be effective in the treatment of lung lesions caused by smoking. This study aimed to assess the effects of indoor second-hand cigarette smoke on respiratory mechanics and lung tissue, in addition to investigating the potential benefit of Eucalyptol against lung damage caused by this type of aggression. The experiments were conducted for 14 days with 40 BALB/c mice, divided into 5 groups: a control group, two groups nebulized with saline solution, divided into active and passive (second-hand) exposure to CS, two groups pre-treated with eucalyptol (10 mg/mL by nebulization) divided into active and passive exposure to CS. Lung mechanics data were collected on a flexiVent® small animal mechanical ventilator. In addition, ex vivo analysis of lung tissue micromechanics, morphometric analyzes and qualitative analyzes of lung tissue were performed. The results showed that 14 days of second-hand exposure generated significant tissue damage, causing infiltration of inflammatory cells and altering respiratory mechanics. However, pre-treatment with eucalyptol was able to prevent all changes caused by CS in both exposure protocols. We conclude that indoor second-hand smoke is capable of causing damage similar to active tobacco consumption and that Eucalyptol can be used as a preventive or nutritional resource against the changes caused by the inhalation of cigarette smoke.
FIXED OIL DERIVED FROM Caryocar coriaceum (PEQUI FRUIT) PREVENTS TISSUE AND FUNCTIONAL ALTERATIONS IN THE RESPIRATORY SYSTEM INDUCED HOUSEHOLD AIR POLLUTION ORIGINATING FROM BIOMASS
Authors: Sousa Allison Matias de , Gondim Fladimir de Lima , Santos Gilvan Ribeiro dos , Moura Marcelle Ferreira , Ferreira Ruth Mesquita , Serra Daniel Silveira , Pimenta Antônia Torres Ávila , Oliveira Mona Lisa Moura de , Cavalcante Francisco Sales Ávila
Published: August 2023

The reuse of biomass residue can be in different ways, such as pellets obtained through the compaction of green coconut shell. Despite the advantages, studies relate the burning of biomass as the main source of household air pollution. Indoor pollution is also correlated with serious consequences for groups considered at risk, such as asthmatics. As a result, the population is looking for alternative and low-cost treatments through natural products with anti-inflammatory characteristics, such as the fixed oil of Caryocar coriaceum (CC). In the present study, we evaluated the effects of oral CC ingestion on the respiratory system of mice submitted to a model of chronic exposure to smoke from the combustion of coconut shell pellets (CSP) and submitted to the OVA-induced asthma model. We performed analysis of the gaseous composition in the exposure chamber and analyzes of different aspects of the respiratory system. CC could prevent inflammatory cell infiltration and alveolar collapse. Furthermore, it was able to avoid changes in the airway resistance, tissue resistance, elastance, compliance and inspiratory capacity. Our findings demonstrate the effects of long-term exposure to indoor pollution and suggest that dietary intake of CC may be a strategy to prevent respiratory diseases.
Features of the development of a unique legume-rhizobium symbiosystem under conditions of metal-induced stress
Authors: Puhalsky Ya. V. , Loskutov S. I. , Vorobyov N. I. , Laktionov Yu. V. , Kozhemyakov A. P.
Published: August 2023

The development of legume-rhizobium symbiosystems based on the mutant pea genotype SGECdt (Pisum sativum L.) and its wild line SGE grown on a medium supplemented with toxic concentrations of Cd and Co was evaluated under the conditions of a summer greenhouse experiment. Plants were inoculated with a consortium of endomycorrhizal fungus Glomus sp.1Fo, nodule bacteria Rhizobiom leguminosarum bv. viciae and associative ACC-utilizing rhizobacteria Variovorax paradoxus 5C-2. Heavy metals significantly inhibited the growth of uninoculated and inoculated wild line SGE plants compared to SGECdt plants. The content of Cd in the shoots of plants of both genotypes increased in the presence of a toxic concentration of Co, while the latter, on the contrary, decreased. The same effect persisted after inoculation with microorganisms. The introduction of microbes leveled the toxic effect of heavy metals and increased the biomass in both pea genotypes in the absence of the introduction of heavy metals. The microbial consortium also contributed to an increase in the transport of biophilic microelement antagonists to the aerial organs of the pea. In general, based on the results of fractal calculation, despite growth inhibition, the wild line showed higher values of the degree of organization of microelements inside shoots and seeds than the mutant genotype. The stagnation or decrease in the microelement bioconsolidation indices in the homeostasis of shoots of the mutant line can probably be interpreted by the redistribution of the supply of food sources between the partners of the symbiostem, in favor of microsymbionts. An increase in the indicators of the bioconsolidation index in seeds can be considered a positive effect, since the best mobilization of trace elements in their cotyledons, in addition to increasing the germination energy of the offspring, will favorably affect the increase in the adaptive potential of plants.
Estimation of the grain, sweet and grass sorghum samples for resistance to low above zero temperatures seedlings
Authors: Gaze V. L. , Lobunskaya I. A. , Kostylev P. I. , Kovtunov V. V.
Published: August 2023

Relevance. Increasing the cold resistance of heat-loving crops is an urgent problem of breeding. During germination, seeds and seedlings are exposed to temperature stress, which has a negative effect on plants, and therefore the duration of the growing season increases, yields and product quality decrease. The article presents experimental data on the assessment of resistance to low positive temperatures of grain sorghum, sugar and herbaceous selection «ANC “Donskoy”». The purpose of the study is to identify sources tolerant to the cold of the breeding material of grain sorghum, sugar and herbaceous.Methods. The research was conducted in the Laboratory of Plant Physiology of the Federal State Budgetary Institution «ANC “Donskoy”» from 2019 to 2022. Diagnostics of cold resistance was carried out at the initial stage of plant development by a method in which seeds were germinated under the influence of low positive temperatures (8 °C), followed by their growth at an optimal temperature (25 °C).Results. Varieties of different types of sorghum resistant to low temperatures have been identified. Seed germination at low positive temperatures was 93.4% and 91.4% for herbaceous and sugar sorghum, and 79.1% for grain sorghum. There have been identified such cold resistant samples of different sorghum samples, characterized by high germination rates and intensity of seed growth in the initial period as the grain sorghum samples (Demetra x ZSK 404/17’, Demetra x Uch. 42/20 and Demetra x ZSK 20/10), the sweet sorghum samples (Demetra x KD-388, Demetra x South and APV-1115 x KL 12198), the grass sorghum samples (APV-1115 x Ch 4, Demetra x LIK-2011 and APV 1115 x Sv. 4).
The reaction of fiber flax (Linum usitatissimum L.) to the content of aluminum ions in vitro culture
Authors: Proletova N. V.
Published: August 2023

Relevance. The influence of unfavorable environmental factors is one of the reasons for the low realization of the biological capabilities of modern flax varieties in production conditions. Cultivation of flax on soils with strongly acidic (pHKCl 4.5 and below) and neutral (pHKCl over 6.0) reactions leads to a significant decrease in the productivity of fiber and seeds. Biotechnological methods are effective in creating new forms with altered features and properties.Methods. The studies were conducted in vitro. The source material is seeds and hypocotyl segments of flax varieties-dolguntsa Impulse, Phoenix, Leader, S-108, Soyuz. The selective agent in the studies was aluminum salts in the form of AlCl3 at concentrations of 0 (control — H2O dist. / nutrient medium (without selective agent), 44 mg/l, 64 mg/l, 84 mg/l.Results. The toxic effect of AlCl3 on the germination of fiber flax seeds, the formation of primary roots and seedlings — hypocotyls of the varieties used was revealed. The indicator of the value indicating the length of primary roots in germinated fiber flax seeds decreased on the seventh day with an increase in the concentration of the AlCl3 solution. The highest sensitivity to the content of aluminum ions was shown by varieties S-108, Leader and Soyuz. This was expressed in a decrease in the length of the hypocotyl with an increase in the concentration of aluminum ions in the solution. In genotypes in all variants of studies on a selective medium containing AlCl3, a morphogenic callus was formed. The frequency of formation of morphogenic calli was different depending on the concentration of AlCl3 in the cultivation medium. A trend towards a decrease in the number of morphogenic cells with an increase in the concentration of aluminum ions was observed in all varieties. In less sensitive varieties (Impulse and Phoenix), the amount of morphogenic callus formed was higher than in more sensitive ones (C-108, Soyuz, Leader). Under selective conditions, shoots of flax of the studied varieties resistant to AlCl3 were obtained.
Study of the baking qualities of a new variety of spring soft wheat Maestro depending on the level of mineral nutrition
Authors: Kokoreva V. G. , Gladysheva O. V. , Barkovskaya T. A.
Published: August 2023

Relevance. To ensure food security, it is necessary to increase the range of varieties of domestic selection in the conditions of the Central Non-Black Earth Region.Methods. The object of research is a variety of spring soft wheat Maestro. Medium-ripened, resistant to lodging and moderately resistant to diseases. The scheme of the experiment: 1. (NPK)0 — control; 2. (NPK)64 (before sowing); 3. (NPK)64 (before sowing) + N30 (in the phase «beginning of tillering»); 4. (NPK)64 (before sowing) + N30 (in the phase «the beginning of tillering») + N15 (exit to the tube). The studies were conducted according to generally accepted methods.Results. It was found that the variety is well responsive to mineral nutrition. The increase in yield varied from 1.69 t/ha (NPK)64 to 1.74 t/ha ((NPK)64 + N30). The weight of 1000 grains increased by 1.8–2.2 g, or 5.0–6.1%, the protein content in the grain — by 0.8% against the background of 0.15–0.37% with nitrogen fertilizing, the gluten content — by 1.0–2.0%. The impact on the baking qualities of grain was assessed. Sedimentation increased after application of basic fertilizer (NPK)64 and additional nitrogen fertilizing ((NPK)64 + N30, (NPK)64 + N30 + N15) by 3–6 ml, or by 8.1–16.2%, the maximum overpressure (P) is 4.2–8.3%, the deformation energy of the test (W) is 13.7–22.4% higher than the control. Correlation analysis was carried out and strong significant correlations were revealed in the indicators «yield» and «gluten content in grain» (r = 0.97), «yield with sedimentation» (r = 0.99), «protein content in grain» and «maximum excess pressure» (r = 0.99). The calculated coefficient of variation (Cv), according to all signs studied in the experiment, did not exceed 10%.
Evaluation of the biochemical composition and commercial qualities of introduced apple varieties in the conditions of Dagestan
Authors: Shakhmrzoev R. A.
Published: August 2023

The weight of a complex of unfavorable factors negatively affects the quality and sustainability of the resulting fruit products. One of the ways to increase the resistance of perennial plantations is the cultivation and introduction of apple varieties into the assortment that are complexly resistant to dominant diseases and stress factors. The main important property of varieties is the commercial quality and biochemical composition of fruits, which determine the main directions and taste qualities. Observations by IMI revealed patterns in the passage of the main phenological phases of the development of apple varieties, characterizing the greatest intervarietal variability, determined the dates characterizing the beginning and end of flowering, depending on the ripening period. The earliest flowering (13.04) and a long 16 days was noted in the summer variety of the Feya apple tree, and later in the late ripening Renet Simirenko (27.04) with a flowering time of eight days. Apple-tree varieties with high resistance to scab and powdery mildew were selected according to the ripening time: summer — Fortuna, autumn — Carmen and Talisman, winter — Talida, Nika. Identification of varietal characteristics of commercial qualities of fruits by attractiveness (fruit weight, taste, appearance) and varieties with a high content of dry matter (Fortuna, Nika), vitamin C — flying varieties Feya, Fortuna (17.0–14.5 mg / 100 g) were selected.
Evaluation of the antioxidant and antimicrobial activity of plant bioactive compounds as natural preservatives
Authors: Orlova E. S. , El-Sohaimy S. A. , Rebezov M. B.
Published: August 2023

Relevance. Natural preservatives such as salt or sugar can be harmful to human health if consumed in excess. Artificial preservatives often use synthetic chemicals that are considered safe by the FDA. A more serious health problem associated with artificial preservatives is that they are often found in unhealthy, processed foods.Methods. The monographic method was used in the work, as well as methods of analysis, systematization, comparison, generalization. The search for data sources was carried out in scientific electronic libraries and search engines eLIBRARY.ru, Science Direct, Scopus, ResearchGate and Cyberleninka portals.Results. Apple peel extract showed high antioxidant activity and effectively slowed down lipid oxidation. At a concentration of 50 micrograms/ml, the OH removal activity was 57%. The antibacterial activity of sea buckthorn seeds is 200–350 mcg/ml, expressed in a minimum inhibitory concentration against various grampositive and gram-negative bacteria, the antioxidant activity is 40,379–93,473, expressed as a percentage.Antioxidant phenolic compounds present in the seeds and skins (meal) of grapes account for 60–70% of the total polyphenols in grapes.Total antioxidant activity for black currant leaves. was 44.51 ± 1.72%.Summing up the comparison of the antioxidant activity of the selected sources, we can conclude that the source that showed the highest antioxidant activity is grape cake. However, if we pay attention to the climatic factor, in the conditions of the Russian Federation it is most expedient to use the peel of apples with an antioxidant activity of 57%, in view of the abundance of this product and the ease of its cultivation
Circovirus as a factor controlling the effectiveness of pregnancy in sows
Authors: Burkov P. V. , Derkho M. A. , Rebezov M. B. , Scherbakov P. N.
Published: August 2023

The results of a microscopic examination of the internal organs of virally aborted fetuses are presented in order to determine the causes of reproductive losses in conditions of subclinical circovirus infection in sows. The material of the study was the tissues of the liver, placenta, umbilical cord, spleen and brain of abortion fetuses of sows whose pregnancy was interrupted in the last trimester of pregnancy. They had clinical signs of diseases associated with PCV-2 infection. It has been established that the PCV-2 virus has the ability to penetrate the feto-placental barrier from the mother's body; due to infection of the umbilical cord and placenta, it enters the fetus, in which it exhibits tropism in relation to the cells of the liver, spleen and brain. The development of the virus in the cells of these organs is the cause of the development of inflammatory, dystrophic and necrotic processes in them, affecting the processes of their intrauterine development, therefore in the last trimester of pregnancy, the cells of the liver, spleen and brain do not have functional properties corresponding to the duration of pregnancy, which affects their viability. The study demonstrates the role of circovirus infection in the formation of reproductive losses in sows in industrial conditions.
To study the sensitivity of field strains of Str. agalactiae and Str. uberis — causative agents of cow mastitis to a drug based on marbofloxacin
Authors: Yavnikov N. V. , Kugelev I. M. , Kapay N. A. , Moskvina A. L.
Published: August 2023

An increase in the number of resistant strains of mastitis pathogens Str. agalactiae and Str. uberis is one of the causes of massive subclinical and clinical mastitis in cows. The aim of the study was to study the sensitivity of field strains of Str. Agalactiae and Str. uberis to the drug based on marbofloxacin «Marboflocin 10%» (LLC «AleksAnn»), as well as to a number of the most commonly used antibacterial drugs (ABP). Sensitivity to marbofloxacin was determined by the method of serial dilutions, to other antibacterial drugs — by the disco-diffusion method. 15 samples of breast secretions from cows with a clinical form of mastitis were examined, from which 15 cultures of streptococci were isolated, including Str. agalactiae and Str. uberis — in 53.3% of the samples. All isolated cultures of Str. Agalactiae and Str. uberis were susceptible to marbofloxacin. The mean value of the minimum inhibitory concentration (MIC) of marbofloxacin for cultures of Str. uberis is 0.50 µg/ml, and for Str. agalactiae — 0.44 ± 0.13 µg/ml. To other antibacterial drugs, the studied cultures of Str. uberis and Str. agalactiae showed different sensitivity, resistance to amoxicillin was revealed, incl. with clavulanic acid, tylosin
Comparative assessment of morphofunctional properties of the udder of the first-calf cows the caucasian brown breed of various genotypes
Authors: Muradyan A. M.
Published: August 2023

Relevance. The caucasian brown breed of cattle is the most common in Armenia. It has been bred in the republic for more than a century and, due to its low milk productivity and the form of the udder undesirable for machine milking, needs further improvement. Consequently, the study of the morphofunctional features of the udder of caucasian brown cows of various genotypes in the conditions of Armenia is necessary and relevant for science and practice.Methods. The object of the study is the first-calf cows of the Caucasian brown breed of various genotypes. For the experiment, 4 groups of first-calf cows of various genotypes were formed, 20 heads each: the control group — purebred caucasian brown cows first-heifers; 1st experimental — half-blood crossbreeds (1/2 caucasian brown x 1/2 holstein); 2nd experimental — two-breed crossbreeds (3/4 caucasian brown x 1/4 holstein); 3rd experimental — three-breed crossbreeds (5/8 caucasian brown x 1/8 jersey x 1/4 holstein). In the second and third months of lactation, the udders of experimental groups of animals were examined and studied by visual assessment, taking measurements and calculation methods.Results. A comparative study of the morphological features and functional properties of the udder of firstcalf cows of various genotypes has shown that the crossing of Caucasian brown cattle with producing bulls of Holstein and Jersey breeds has a positive effect on the level of milk productivity, the shape of the udder of cows and the rate of milk production, which is of great importance in industrial milk production technology.
The effect of substances isolated from an aqueous extract of oak bark on the concentration of chemical elements in the body of broiler chickens
Authors: Duskaev G. K. , Kvan O. V. , Sheida E. V. , Rakhmatullin Sh. G. , Levakhin G. I.
Published: August 2023

Relevance. A comprehensive study of the properties of plants containing phytobiotic components will make it possible to widely use plant extracts in animal feeding as biologically active additives of the latest generation based on raw materials of natural origin. The aim of the work is to study the effect of substances isolated from an aqueous extract of oak bark (BBVECD) on mineral metabolism in the body of broiler chickens.Methodology. The object of the study are broiler chickens of the Smena-8 cross. 120 heads of broiler chickens were selected for the experiment, which were divided into 4 groups by the method of analogues (n = 30). The control group received the basic ration (RR), I experimental — RR + BBVECD (1 ml/kg of live weight.), II experimental — RR + BBVECD (2 ml/kg of live weight.), III experimental — RR + BBVECD (3 ml/kg of live weight). The analysis of chemical elements in the obtained ash of the studied samples was carried out using the «Elan 9000» mass spectrometer and the «Optima 2000 V» atomic emission spectrometer.Results. The results obtained in the context of the effect of BBECD on mineral metabolism in broiler chickens should be discussed in the context of already available data that a number of compounds found in plant extracts may have the ability to chelate transition metal ions, especially Fe (II) and Cu (II), which is important. During the experiment, it was shown that the introduction of oak bark extract into the diet of broiler chickens mainly led to the accumulation of macronutrients (potassium — from 0.8 to 6.24%, magnesium — from 1.02 to 7.14%, phosphorus — from 5.31 to 7.9%) and essential trace elements in muscles (cobalt — 1.5 times, chromium — 3.67 times, lithium — 1.67 times, nickel — 4 times, silicon — 1.34 times), as well as to reduce the content of toxic and conditionally toxic elements in them: aluminum — 1.62 times, lead — 2 times. In this case, the most appropriate is the use of oak bark extract in a dose of 1 ml/kg of live weight of poultry.
Testing of fungicidal treatments of flax seeds and crops
Authors: Kudryavtsev N. A.
Published: August 2023

The relevance and economic significance of the development are determined by its relevance to the agroindustrial complex of Russia with the possibility of increasing the effectiveness of flax protection from diseases, replacing old fungicides with new ones, contributing to the improvement of economic indicators of flax cultivation technology.The scientific novelty is connected with the priority of the search for acceptable technological methods for flax growing in the Russian Federation, including effective plant protection measures.Methods. Tested during field experiments on registration tests of pesticides and determination of the effectiveness of the use of research results in agriculture.Results. A fungicide new to flax growing, Abiga-Peak, has been identified, which has shown in field registration tests an effective protective effect against a number of flax diseases (anthracnose, ozoniosis (mottling), septoria (pasmo), aureobazidiosis (polysporosis). The positive effect of the fungicide AbigaPeak on the yield of flax products was noted. In a production environment with the use of an automated etching machine PS-10A and a spraying unit OP-18-2500 + MTZ-1221.2 even more convincingly shows an effective reliable reduction in the manifestation of flax diseases and an increase in its yield associated with the use of the drug Abiga-Peak. The treatment of flax seeds and crops with the studied preparation did not negatively affect the content of bacteria, fungi and actinomycetes in the soil.
Manufacture of Polymer Concrete Based on Snake-Fruit Seeds (Salacca zalacca) and Sawdust with Polyester Resin as an Adhesive
Authors: Harahap Mahdi Jauhar , Sitorus Zuriah
Published: August 2023

This study aims to determine the effect of adding snake-fruit (Salacca zalacca) seeds and sawdust on polymer concrete's physical and mechanical properties. The results showed that the highest physical properties were 1.27 g/cm3 density, 12.5% porosity, and 13.22% water absorption. The lowest physical properties are a density of 0.85 g/cm3, porosity of 2.65%, and water absorption of 2.07%. The highest mechanical properties are compressive strength of 16.70 MPa, tensile strength of 4.39 MPa, and flexural strength of 7.93 MPa. The lowest mechanical properties are compressive strength of 6.80 MPa, tensile strength of 1.11 MPa, and flexural strength of 1.50 MPa. SEM test results showed that the microstructure of polymer concrete showed differences between concrete samples A1 (consisting of 35 g of snake-fruit seeds, 15 g of sawdust, and 15 g of polyester resin) and polymer concrete samples B1 (consisting of 30 g of snake-fruit seeds, 15 g of sawdust, and 20 g of polyester resin). The SEM analysis of the A1 concrete sample reveals a dark surface color and conspicuous white lumps, which are attributed to polyester resin and arise from inadequate mixing of ingredients. In the case of sample B1, a higher concentration of visible resin lumps is observed.
The Role of Vitamin D in Pregnant Women in Birth Weight of Neonates
Authors: Rajuddin Rajuddin , Moulina Derevie Hendryan , Munawar  , Cut Meurah Yeni  , Hilwah Nora
Published: August 2023

Objective: To determine the relationship between serumvitamin D levels in third trimester mothers and newbornbirthttweight.Method: The study was conducted at the maternity wardof Dr. Zainoel Abidin General Hospital in Banda Aceh,Indonesia. Maternal and infant serum vitamin D levelswere measured using the Automatic ChemiluminescenceImmunoassay Analyzer (CLIA) method. Blood samples werecollected from mothers in the third trimester and frominfants after delivery. Spearman's correlation rank test wasemployed with a confi dence level of 95%. Vitamin D levelswere categorized as suffi cient, insuffi cient, and defi cient.Results: A total of 39 pregnant women with an averageage of 30.38 ± 6.21 years participated in the study, with apredominance of 38-39 weeks of gestation (35.9%). Themean vitamin D levels in mothers and neonates were 17.4ng/mL and 17.6 ng/mL, respectively (p = 0.003, R = 0.462).The average birth weight of the babies was 3,100 grams,ranging from 2,100 grams to 4,200 grams (p = 0.185, R =0.217). Both variables showed a positive correlation withvarying strength of the relationship.Conclusion: Maternal serum vitamin D levels in the thirdtrimester exhibited a positive correlation with serum vitaminD levels in neonates with moderate strength, but therewas no correlation with birth weight. The evaluation ofmaternal third-trimester serum vitamin D levels can serve asa predictor of neonatal vitamin D levels.Keywords: birth weight, neonates, pregnancy, vitamin D.

AbstrakTujuan: Untuk menilai pengaruh hubungan kadar vitaminD serum ibu trimester ketiga terhadap kadar vitamin D danberat badan neonatus yang dilahirkan.Metode: Penelitian ini studi observasional korelatif dengandesain potong lintang yang dilakukan pada kamar bersalinRSUD dr. Zainoel Abidin Banda Aceh. Pengukuran kadarvitamin D serum ibu dan bayi dilakukan dengan metodeAutomatic Chemiluminescence Immunoassay Analyzer(CLIA). Analisis data dengan melakukan Uji Spearman’scorrelation rank test untuk menilai kekuatan hubungan duavariabel.Hasil: Sebanyak 39 ibu hamil usia 30,38 ± 6,21 tahun terlibatdalam penelitian ini dengan dominasi usia kehamilan 38–39minggu (35,9%). Rerata kadar vitamin D ibu dan bayi secaraberurutan adalah 17,4 ng/mL dan 17,6 ng/mL (p = 0,003,R = 0,462). Rerata berat badan bayi yang dilahirkan adalahsebesar 3.100 gram dengan rentang 2.100 gram hingga4.200 gram (p = 0,185, R = 0,217). Kedua variabel didapatkankorelasi positif dengan kekuatan hubungan bervariasi.Kesimpulan: Kadar vitamin D serum ibu trimester ketigaberkorelasi positif terhadap kadar vitamin D serum neonatusyang dilahirkan dengan kekuatan sedang namun tidakberkorelasi terhadap berat badan lahir bayi. Kadar vitaminD serum ibu pada trimester ketiga dapat dijadikan prediktorkadar vitamin D neonatus saat dilahirkan.Kata kunci: berat badan lahir, kehamilan, neonatus,vitamin D.
THE INFLUENCE OF CREATIVITY ON THE DEVELOPMENT OF THE ENTERPRISE'S BUSINESS ORGANIZATION
Authors:   National Aviation University, Ostapenko Tetiana , Hlavatska Yuliia ,   National Aviation University
Published: August 2023

The relevance of the chosen research topic is determined by the fact that today the creative component is being removed from the management system. It is necessary to be employees of the enterprise, the result of labor, and the production process must be creative. Every aspect of the business should be aimed at meeting the highest needs of the human employee and the human manager. Management activity is inherently creative because managing means creating conditions for relations between people and bringing them to new career milestones. The basis of the creative process is cultural traditions because language and cultural works influence a certain way of thinking and the formation of emotional intelligence. The cultural creative process involves the separation of global and national, spiritual and material, etc. The creative process involves combining the formation of the organizational structure of enterprise management. The organizational structure can be traditional or marketbased, depending on the specific case of formation. The enterprise’s organizational structure has creative approaches when each structure is unique. The number of enterprises, there are so many forms of the CMO. The definition of the creative process was based on the example of Ukrainian company "Rosa", produces items for the creative process of children and adults. The period of the last 12 months was analyzed. And it was a multivariate regression was performed as a dependence of the net profit of the enterprise on expenses and materials and labor costs, which can be considered innovative. The coefficient of determination is R=0.99, which is rather high which is quite high and indicates a close relationship between the phenomena. Thus, the company has an innovative and creative development perspective. The OCS of the studied enterprise demonstrates the optimal approach to building relationships in the team and building communication based on emotional intelligence.
GASTRO TOURISM IS RELEVANT TO DEVELOPMENT SPHERES OF TOURISM
Authors:   Vinnytsia National Agrarian University, Tabenska Oksana
Published: August 2023

In the conditions of transformation of global economic relations, international trade in services offers research and implementation of tourist services to meet the demand of various categories of consumers. Gastronomic tourism is one of the options for recreation in modern conditions. A feature of gastronomic tourism in Ukraine, as well as in the countries of cross-border cooperation, are authentic natural food products, which are the basis for creating unique local dishes and drinks. The article analyzes the mechanisms of the functioning of gastrotourism as an important element of the development of tourism at the current stage, researches the foreign and domestic experience of culinary tourism, types of gastronomic tours, as well as GIS technologies that provide an opportunity to effectively search for interesting gastronomic locations in a certain territory. The "Strategy for the development of tourism until 2030" and the creation of the Vinnytsia industry association of hospitality "Bread Salt" were considered, the Gastromap – a new tourist map of Vinnytsia, as well as architectural monuments, interesting attractions and museums, and the "Cherry menu" in food establishments of the city of Vinnytsia were analyzed. The strategy of tourism development in the Vinnytsia region was studied, and a project model of relations in the tourism and recreation cluster "Vinnytsia" was proposed. The article analyzes the real state of activity of restaurant enterprises during the large-scale in Ukraine. The directions of activity of this business segment were considered. Therefore, given the current situation the restaurant business should improve, modernize and, first of all, pay attention to solving safety issues both for staff and for consumers. The creation of a number of tourist and excursion routes will allow to harmoniously combine attractive conditions of rest and travel to fully satisfy the needs of the most demanding tourists. Vinnytsia has all the prerequisites for the intensive development of domestic and foreign tourism, namely: features of the geographical location and relief.
EXPENSES OF A HOUSING CONSTRUCTION DEVELOPER: TYPES, STRUCTURE AND ACCOUNTING AND ANALYTICAL REFLECTION
Authors:   Lviv Polytechnic National University, Voskresenska Теtiana
Published: August 2023

The article focuses on the importance of accounting for expenses of a housing construction developer, since they affect the determination of the final cost of housing construction. The price attractiveness of the entire residential complex depends on the accuracy of the cost of housing construction and its distribution among individual residential real estate objects. The study shows the dynamics of the cost of 1 m2 of living space in terms of individual settlements, according to which it is determined that the highest cost of housing is in the capital, the lowest – in Kirovohrad Oblast. It is noted that in addition to the differentiation of the cost of residential m2 by oblast, the cost of 1 m2 of living space depends on the location of the residential complex (business centre, residential area of the city, etc.). It is argued that the cost of housing construction is the basic basis for determining the price of housing construction. The paper presents an indicative structure of costs for the construction of a residential complex. According to it, it is determined that the largest share in the total cost of financing housing construction is the cost of construction of the frame (40%) and the cost of finishing works. It is noted that over the past 10 years, the developer has spent a significant amount of money on the construction of a residential complex to improve the adjacent territory in order to increase the attractiveness of the residential complex. It is considered that the main production costs for the construction of a residential complex by a developer are accounted for in Account 23, and after the construction work is completed and the residential complex is put into operation, the amount of accumulated costs is written off and the sales value of the construction object as a whole, individual apartments and 1 m2 of living space is determined accordingly. It is determined that if a developer simultaneously implements several housing projects, general production costs arise, which are registered in Account 91 and distributed among individual construction projects. In addition to the costs directly related to the construction object, the customer also bears the costs associated with the management of the enterprise, which are recorded in Account 92, and the costs associated with the sale of apartments (Account 93), unless housing intermediaries are involved in this process.
INNOVATIVE ACTIVITY OF BUSINESS-STARTUPS: THE CURRENT STATE AND PROSPECTS FOR THE POST-WAR RECONSTRUCTION OF THE UKRAINIAN ECONOMY
Authors:   Leonid Yuzkov Khmelnytskyi University of Management and Law, Vahanova Lyudmila , Mantur-Chubata Olena ,   Khmelnytskyi National University
Published: August 2023

In the post-war period, the Ukrainian authorities should understand the importance of business development, its role and place in the transformation of the economy and the development of local economic development. The article studies the subjects of the startup ecosystem (startup companies, service companies, state and local authorities, investors, competence centers, expert environment, change agents, infrastructure companies, stock exchanges and brokerage companies) and their leading functions. The article identifies the newest global startups and the most successful domestic startups in the pre-war period. Even during the war, Ukrainian startups (CareTech Human, Lab, Mindly Pleso therapy, MISU, Cardio.AI) continue to develop and are supported internationally. Today, at the level of our country, thanks to the institutional support of the Government, the foundation is being laid for creating a favorable environment for the development of startups, in particular for the development of small business: transfer of the Innovation Development Fund to the management sphere of the Ministry of Digital Transformation; grant funding and technology support needed to strengthen the country. It has been found that for the development of a national system of "sustainable development – security," the core should be innovative security with the supporting effect of high-quality socio-economic deve­lopment of national security. The main tasks of managing the component in the context of sustainable development and post-war recovery are: 1) the use of new technologies, the digital economy and science in solving the problems of recovery; 2) the use of new technologies as a tool for creating new jobs and development opportunities; 3) strategic forecasting to ensure that technologies meet the needs and requirements in various industries; 4) strategic forecasting and evaluation activities. Emphasis is placed on the fact that systemic innovation policy, regardless of the types of innovations, must meet the goals of sustainable development. The paper presents the ratio of the growth of innovation activity of Ukrainian startups (product startups, MilitaryTech and cybersecurity, HealthTech and mental health, FoodTech and sustainable development, EdTech and educational projects, projects for the restoration of infrastructure and construction) to further assess their impact on the economic development of the region and the effectiveness of public management decisions by local authorities in terms of institutional support, in accordance with the Sustainable Development Goals, regions and society as a whole.