An observational study on assessment of thyroiddysfunction and its co-existing conditions in a government area hospital
Authors:   PHARM.D, Medarametla Anjamma Mastanrao College Of Pharmacy, Kesanupalli (PO), Narasaraopet- 522601, Palnadu Dist. (AP), M Vishnupriya. , M Priyanka. ,   PHARM.D, Medarametla Anjamma Mastanrao College Of Pharmacy, Kesanupalli (PO), Narasaraopet- 522601, Palnadu Dist. (AP), Ch Kartheek. ,   M.Pharm, Associate Professor, Department of Pharmacology, Medarametla Anjamma MastanraoCollege Of Pharmacy, Kesanupalli (PO), Narasaraopet- 522601, Palnadu Dist. (AP).
Published: June 2024

Introduction: Healthcare professionals have a great deal of difficulty when thyroid dysfunction coexists with other medical disorders, making diagnosis and treatment more difficult. Thyroid dysfunction is frequently accompanied withconditions such as cardiovascular illnesses, diabetes mellitus, and autoimmune disorders, which can exacerbatepatient morbidity and affect treatment results overall. Comprehensive patient management requires an understandingof the relationships between comorbid diseases and thyroid dysfunction. The objective of this study is to improvetreatment practices and further our understanding of the intricate interactions between thyroid dysfunction andcomorbid illnesses by examining the incidence of thyroid dysfunction in a hospital context. In the end, our researchaims to ensure comprehensive and successful treatment options for individuals with thyroid dysfunction, improvingtheir management and care. Methods and Material: This was a observational study conducted in a Government area hospital in the duration of 6 months. In this study wecollected demographic details, past medical and medication history, current therapy and respective laboratory datai.e., thyroid profile of a patient. The associated co-existing conditions were studied and evaluated using SPSSsoftware Results: This study demonstrates that maximum number of patients suffering with thyroid disorders are females. Age group of 31-40 male are more likely suffering from thyroid disorder. Most of the people are suffering from hypothyroidism. People who are using levothyroxine 50 mcg are more when compared with other doses and people using bothcarbimazole and methimazole are same. People suffering from CVS are more than other co-morbidities.In aspect of both hypothyroidism and hyperthyroidism, females are more prone to CVS compared to malesConclusion: The study's combined data demonstrated that, in comparison to hyperthyroidism, more occurrences of hypothyroidism were observed in females than in males. Although the entire sample size indicates that females aremore susceptible to thyroid problems, men (38%) and females (27%) of the same age are more impacted by thyroidabnormalities. As per the comorbidities mentioned in our study, CVS accounts for 24%, with DM (12%), CNS (6%), ortho (5%), toxicity (4%) and other comorbidities following closely after. Relevant cardiovascular issues arise fromeither increased or decreased thyroid hormone activity on certain molecular pathways in the heart and vasculature Keywords: Thyroid Disorders, Hypothyroid, Hyperthyroid, Comorbidities