bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of ocean heat content from two eddy-resolving hindcast simulations with OFES1 and OFES2
Authors: Liao Fanglou , Wang Xiao Hua , Liu Zhiqiang
Published: April 2021

Abstract. The ocean heat content (OHC) estimates from high-resolution hindcast simulations from the Ocean General Circulation Model for the Earth Simulator Version 1 (OFES1) and Version 2 (OFES2), and a global objective analysis of subsurface temperature observations (EN4.2.1) were compared. There was an OHC increase in most of the global ocean over a 57-year period, mainly a result of vertical displacements of neutral density surfaces. However, we found substantial differences in the temporal and meridional distributions of the OHC between the two OFES hindcasts. The spatial distributions of potential-temperature change also differed significantly, especially in the Atlantic Ocean. The spatial distributions of the time-averaged surface heat flux and heat transport from the OFES1 and OFES2 were highly correlated, but differences could be seen. However, these differences, more specifically in the heat transport, were only partially responsible for the OHC differences. The marked OHC differences may arise from the different vertical mixing schemes and may impact the large-scale pressure field, and thus the geostrophic current. The work here should be a useful reference for future OFES users.
Flow separation, dipole formation and water exchange through tidal strait
Authors: Nøst Ole Anders , Børve Eli
Published: April 2021

Abstract. We investigate the formation and evolution of dipole vortices and their contribution to water exchange through idealized tidal straits. Self-propagating dipoles are important for transporting and exchanging water properties through straits and inlets in coastal regions. In order to obtain a robust data-set to evaluate flow separation, dipole formation and evolution and the effect on water exchange, we conduct 164 numerical simulations, varying the width and length of the straits as well as the tidal forcing. We show that dipoles are formed and start propagating at the time of flow separation, and their vorticity originates in the velocity front formed by the separation. We find that the dipole propagation velocity is proportional to the tidal velocity amplitude, and twice as large as the dipole velocity derived for a dipole consisting of two point vortices. We analyse the processes creating a net water exchange through the straits and derive a kinematic model dependent on dimensionless parameters representing strait length, dipole travel distance and dipole size. The net tracer transport resulting from the kinematic model agrees closely with the numerical simulations and provide understanding of the processes controlling net water exchange.
Big Data Affluence in Statistics Application: A Comparison of Real Life and Simulated Open Data
Authors:   Federal Polytechnic, Ilaro, Adeboye Nureni , Olayiwola Oyedunsi ,   Osun State University
Published: April 2021

Large data repositories or database management still remain a mirage and tough challenge to accomplish by most developing countries and establishments around the globe. This necessitates the need to improvise on the gathering of suitable data with a good spread to serve as a complement, in the absence of sufficient real-life data. Statisticians are increasingly posed with thought-provoking and even paradoxical questions, challenging our qualiﬁcations for entering the statistical paradises created by Big Data. Through classroom activities that involved both sourced real-life and simulated big data in R-environment, models were built and estimates obtained from the adopted techniques revealed the robustness of simulated datasets in a unified observation with improved significant values as reflected in the results. Students appreciated the use of such big data as it enhances their machine learning ability and the availability of sufficient data without delay.
Integrating ‘education for sustainable development’ in statistics classes: visual analysis of social and economic data with gapminder
Authors:   University College of Teacher Education Tyrol, Andre Martin , Lavicza Zsolt ,   Johannes Kepler University Linz, Prodromou Theodosia ,   University of New England
Published: April 2021

Sustainable development goals (SDGs) address various aspects of future human development such as poverty, pollution, or climate change. Education for Sustainable Development (ESD) seeks to encourage students to actively participate and consider these issues in sustainable development. Following design-based research approaches, our study aims to identify opportunities for integrating ESD into statistics education. We describe the main features of an ESD-integrated learning trajectory for middle school students exploring sets of ESD related data visually with the software Gapminder. The outcomes of our study suggest that (1) Students’ engagement in forming statistical models of various countries’ sustainable development developed their abilities to generate statistical questions (2) Their intuitive knowledge of statistical concepts was further formalized during their subsequent analyses.
'Este proceso ha sido de piel, no ha sido de escritorio': itinerario del documento de la política pública CaliAfro
Authors: Martínez B. Sandra Patricia
Published: April 2021

En este artículo me propongo analizar el proceso de construcción del documento de la política pública para los afrodescendientes que residen en la ciudad de Cali, Colombia. A partir de la reconstrucción de los distintos momentos que pautaron este proceso (ensamblaje, desplazamiento de significados y discusión), intento resolver interrogantes como los siguientes: ¿Quiénes intervinieron en la elaboración del documento? ¿Qué papel jugaron los saberes expertos en ello? ¿Cómo se tomaron las decisiones de qué incluir y qué dejar por fuera? ¿Qué argumentos e intereses lograron imponerse? Para abordar estas preguntas, me apoyo en algunos autores que han abogado por la consideración de los documentos como un objeto etnográfico, así como en los aportes de la Teoría del Actor-Red para entender el papel que éstos juegan en la producción de lo social.
NEW TRENDS IN MODERN INTERNATIONAL RELATIONS
Authors: PARUBOCHAYA Elena
Published: April 2021

The specific of international relations in recent years has demonstrated the instability of the world system, lack of trust, a trend towards increasing confrontation between international actors. Undermining of the internal political situation in some states of the world system influenced the regional and global level of security and stability. But the vulnerability of the international relations in 2020 has shown the beginning of new geopolitical shifts. The COVID-19 pandemic has accelerated the international system's transformation, reducing the space for building international cooperation, increasing the conflict in the sphere of international relations. Preservation or reaching a new level of international trends characteristic of the last decade, new trends appear that change the entire system of international communication and interaction at the regional, international and global levels.
UNDERSTANDING RUSSIAN SMART POWER: PERCEPTIONS AND IDEOLOGY
Authors: IVANOV Iskren
Published: April 2021

Russian foreign policy today incarnates the double-headed eagle of smart power perceptions and Neo-Eurasian ideology. The main purpose of this article is to examine the emergence and development of Russian smart power by analyzing the foreign policy concepts of the Russian Federation after September 11. In this paper, I will argue that Moscow’s smart strategy is much similar to the American concept of smart power, but only in terms of its purpose. The article’s assertion rests on the assumption that smart power allowed Washington to sustain its global dominance after the terrorist attacks from September 11, and alternately – could help Russia to consolidate Eurasia. The Coronavirus Pandemic, of course, will have long-term consequences for the international security. Finally, I will conclude that if Moscow wants to maintain the Russia-dominated security system in Eurasia, it should develop its original concept of smart power.
القوامة للتي هي أقوم
Authors:   أستاذ مساعد في كلية جدة العالمية، جدة، المملكة العربية السعودية, قارة الدكتورة/ عبير إبراهيم
Published: April 2021

تهدف هذه الدراسة في مسألة القوامة في الشريعة الإسلامية بتبيين أهمية هذا المبدأ وأثره الكبير في استقامة الحياة الأسرية ومن ثم استقامة المجتمع ككل عندما يفقه كل من الزوجين دوره بمعرفة حقوقه وواجباته وفق منظومة ربانية أصيلة ومحكمة، وقد تطرقتُ بمنهج استقرائي ثم نقدي لدراسة السياق الذي وردت فيه القوامة ثم تعريفها، ويلي ذلك مبحث يشرح حال المرأة في عصر الرسالة وما تلا ذلك من عصور الانحدار في الفهم والتطبيق وشرحتُ أسباب تلك القوامة وكم تظلم المرأة في مجتمعات تسعى لتحقيق المساواة التامة بينها وبين الرجل، وبانتحال المرأة مع هذه القوامة من إذعان باختيار أو ترفع ونشوز، ثم توصلتُ - بفضل الله - لنتائج عدة بناء لما تم البحث فيه وجملة من الاقتراحات والتوصيات الهامة التي لا بد منها لأسرة ومجتمع فاضل.
PENGALAMAN PSIKOLOGIS REMAJA GAY PEKERJA SEKS KOMERSIAL DENGAN PERILAKU SEKSUAL BERISIKO TERHADAP PENULARAN IMS DAN HIV - AIDS DI KABUPATEN JEMBER
Authors: Azari Abdul Aziz
Published: April 2021

One of the most risky behaviors for STD transmission and HIV-AIDS is the rise of commercial sex worker activities among homosexuals. A teenager does commercial sex work because of the urge to fulfill needs, which includesphysiological, social, economic and cultural needs. This study aims to analyze the drive behavior and dramaturgyprocesses in gay commercial sex workers. This study uses a qualitative research design with a phenomenologicalapproach. Participants in this study were 5 people with purposive sampling data collection techniques. Data wereanalyzed using Colaizzi technique. The results of this study found that most of the drive behavior performed by gayadolescents is economic necessity, while the dramaturgy process that occurs is the front stage.
FAKTOR YANG BERPENGARUH PADA KUALITAS HIDUP CAREGIVERS PADA INDIVIDU SINDROM DOWN : LITERATURE REVIEW
Authors: Suharta
Published: April 2021

MengasuhindividudenganSindrom Down (SD) denganbanyaknyaketerlambatan dan kecacatanbaiksecara mental maupunfisikmenjadikan orang tua ataupengasuh(caregivers) cenderung mengalami beban yang lebihtinggi, dimanasecaralangsung bepengaruh pada kualitas hidup mereka sebagai caregivers. Tujuan: mengetahui faktor yang berpengaruh pada kualitashidupcaregiversindividudengan SD. Desain: literature review. Metode: Pencarianartikelpada database jurnal yang relevan termasuk Scopus (n=27), Science Direct (n=141), dan Google Scholar (n=170) dengan menggunakan kombinasi pencarian:“quality of life“and “cargivers”or “kualitashidup” and“pengasuh “ or”orang tua” or“pendamping“ and“sindrom down”. Peneliti meninjau (n=10)  artikel dari (n=338) artikel yang diidentifikasi. Hasil: lima jurnal menyebutkan faktor dukungan keluarga, dukungan sosial, status ekonomi, kondisifisik-kesehatan dan penerimaankepadaindividu SD adalahfaktor yang berpengaruh pada kualtiashidupcaregiverKesimpulan: Secara garis besar peneliti menemukan lima faktor yang berpengaruh pada kualitas hidup caregivers anak-remaja dengan SD. Pentinguntukdilakukanpenelitianlebihlanjutterkaitkualitashidupindividu SDdengancakupanyang lebihluas dan beragamgunamendapatkanlandasanteoritissebagaidasaruntukperumusanasuhankeperawatankeluarga dan komunitas.

 

Kata Kunci:KualitasHidupPengasuh, Sindrom Down, Kualitas Hidup, Caregivers.
KONSELING LIFESTYLE MODIFICATION PADA INDIVIDU DENGAN HIPERTENSI DI BONDOWOSO
Authors: SUHARTA, DEVITA MALA ANGGRIANTI
Published: April 2021

Background: Hipertensi dicatat sebagai salah satu permasalahan yang paling umum di negara maju dan negara berkembang. Selain intervensi farmakologi, intervensi non-farmakologi banyak dilakukan dan dikembangkan, salah satunya metode konseling dan modifikasi gaya hidup Method: Desain Penelitian ini menggunakan quasy-experimental design. Sampel dalam penelitian ini adalah 28 responden (rentang usia 30-60 tahun) dengan menggunakan purpossive sampling. Pada penelitian ini dilakukan empat kali pertemuan dalam satu bulan Result: Hasil uji statistik menggunakan independent t-test tidak ditemukan perbedaan yang signifikan antara sebelum dan sesudah perlakuan dimana nilai p value > 0,05 baik pada sistolik dan diastolik sesudah perlakuan (P value>0,885 dan P value >0,52). Conclusion: Secara umum tidak ditemukan perbedaan yang signifikan secara statistik antara sebelum dan sesudah perlakuan namun terdapat perubahan pada nilai mean tekanan darah antara sebelum dan sesudah perlakuan. Perlu diberikan intervensi dalam durasi lebih lama.
MORPHOLOGICAL CHANGES IN KIDNEYS OF CHICKENS IN THE NEPHROSIS-NEPHRITIC FORM OF INFECTIOUS BRONCHITIS
Authors: Zhurov D. O. , Gromov I. N.
Published: April 2021

The article presents data on the study of pathomorphological changes in the kidney of chickens with nephrosis-nephritic form of infectious bronchitis.The formation of protein cylinders of various structures in the renal parenchyma is found. There are also marked serous glomerulitis, vacuolar and granular degeneration, necrobiosis and necrosis of certain portions of the kidney tubules, an increase in the indicators of the plasmacytic reaction.
A Pre Experimental Study to Assess the Effectiveness of Laughter Therapy on Level of Stress among Elderly Residents of Selected Old Age Home, Delhi
Authors: Kaur Nirdeep , Sharma Shailza
Published: April 2021

Background: Mental health plays vital role in older age as at any other time of life. Many old age people find themselves more alone than ever before as longstanding friends and relatives die and family and friends relocate to different geographical areas. The most common emotional disorder in the elderly population is stress. Laughter therapy is very effective to reduce the stress level of elderly residents of old age home. The aim of study is to assess the effectiveness of stress among elderly residents of old age home.
Material and method: A Pre experimental design was used to assess the effectiveness of laughter therapy on levels of stress among elderly residents of old age home, Delhi. A structured stress assessment tool was administered to assess the level of stress.
Result: A pre-experimental study was conducted on 60 subjects of elderly population in selected old age home, Delhi. Pilot study was conducted on 10 subjects to ensure the reliability of the tool and feasibility of the study. The data was collected from month of February 2020 to March 2020.The finding of the study revealed that pre-test stress score, 1(1.7%) had no stress, 19(31.7%) had mild stress, 39(65.0%) had moderate stress and 1(1.7%) had severe stress and the post-test score was 6(10%) had no stress, 50 (83.3%) had mild stress, 4(6.7%) moderate stress and none had severe stress. The mean stress pre-test score was (51.7) and post-test stress score was (34.4). It was found significant association (p-<0.05) on reduction of stress from moderate to mild stress. Hence, laughter therapy was effective in reduction of stress among elderly residents. The association between stress and selected demographic variables (age, sex, marital status, educational status, financial support, social- support, religion, per- capita monthly income and frequency of visit by family members) was determined by using paired “t”-test and chi-square to establish statistical significance. There was no association between the pre interventional levels of stress.
Conclusion: The study highlights that Laughter therapy was effective in reducing the stress levels among elderly residents of Pita Ji old age home, DhashrathPuri, Delhi.

Key words: Assess, effectiveness, Laughter therapy, Stress, Elderly, Old age home.
The Effect of Accounting Disclosure and Environmental Performance, Company Size and Corporate Social Responsibility Disclosure on the Value of Mining Companies Listed on the Indonesia Stock Exchange 2015-2019
Authors: Tanjung Fikry , Bukit Rina Br , Fachrudin Khaira Amalia
Published: April 2021

This study analyzes the effect of environmental accounting disclosure, environmental performance disclosure, company size, and corporate social responsibility disclosure on firm value in mining companies listed on the IDX. This study uses an associative clause design. This research's population and sample are mining companies that publish annual reports and sustainability reports during 2015-2019, totaling 18 mining companies using the purposive sampling method. The number of analysis units used is 90. This study's type of data is secondary data obtained from the IDX website, namely www.idx.co.id. The data analysis technique uses multiple linear regression analysis using the eViews 10 application program. This study indicates that simultaneously environmental accounting disclosure, environmental performance disclosure, company size, and corporate social responsibility disclosure of firm value. However, partially, environmental accounting disclosure has a positive and insignificant effect on firm value, environmental performance disclosure has a negative and insignificant effect on firm value, firm size has no significant positive effect on firm value, and disclosure of corporate social responsibility has a negative but significant effect on firm value.

Keywords: Firm Value, Environmental Accounting Disclosure, Environmental Performance Disclosure, Company Size, Corporate Social Responsibility Disclosure.
Analysis of Factors Affecting Human Development Index in the City of Binjai
Authors: Barus Elisabet Novita , Tarmizi HB. , . Rahmanta
Published: April 2021

This study aims to analyze the Factors That Affect Human Development Index in the City of Binjai with variable observations shopping area in the field of health, education, population, and income per capita. This research is causality by performing multiple regression analysis (Multiple Regression Analysis). The Data used is the data of the year 2005 up to 2019 are presented per semester (n=30 samples). The results of the study concluded that the shopping area in the field of health, expenditure on education, expenditure in the field of population, and per capita income is able to influence the human development index in the local government of the City of Binjai. Based on the value of the coefficient of determination (r-square) of all the variables, it was concluded that per capita income is a variable dominant that affect the human development index in the local government of the City of Binjai.

Keywords: The Human Development Index, A Shopping Area In The Field Of Health, Expenditure On Education, Expenditure In The Field Of Population, And Per Capita Income.
Scytinopogon caulocystidiatus and S. foetidus spp. nov., and five other species recorded from Brazil
Authors: Furtado A.N.M. , Daniëls P.P. , Reck M.A. , Neves M.A.
Published: April 2021

Seven species of Scytinopogon in the Atlantic Forest of Brazil are described. Scytinopogon caulocystidiatus and S. foetidus are proposed as new species based on morphological and molecular data. Five other species are presented: S. chartaceus, S. dealbatus
and S. robustus, originally described from Brazil; and S. pallescens and S. scaber, previously reported for Brazil. Illustrations of the basidiomata and microstructures, including SEM images of ornamented basidiospores, are provided for all taxa. Comparisons with morphologically
similar taxa and a key to the seven species of Scytinopogon known to occur in Brazil are also presented.
Physalidiella pentagona sp. nov. from Guizhou, China
Authors: Xiao Zhong-Jiu , Li Xiao-Xia , Liu Ting , Chen Mo-Fang , Wang Shuang-Shuang , Kong Ya-Ping
Published: April 2021

A new species, Physalidiella pentagona, collected on dead twigs of Lindera communis in Guizhou Province, China, is described and illustrated. The fungus is mainly characterized by differentiated conidiophores with opposite or verticillate short branches and monoblastic,
percurrently extending conidiogenous cells that produce solitary, smooth, quasi-stellate or T-shaped conidia with an approximately pentagonal central cell and two smaller hemispherical lateral cells. A dichotomous key to Physalidiella species is provided.
Blastophragmia plurisetulosa gen. & sp. nov. from China
Authors: Ma Jian , Ma Li-Guo , Cui Ru-Qiang , Kuang Wei-Gang , Zhang Xiu-Guo , Castañeda-Ruíz Rafael F.
Published: April 2021

A new asexual ascomycete genus and species, Blastophragmia plurisetulosa, is described and illustrated from a specimen collected on dead branches of unidentified plants in Hainan Province, China. The fungus is distinguished by macronematous, unbranched, determinate or percurrently
extending conidiophores, and solitary, acrogenous, fusiform to ellipsoidal, 3-euseptate, smooth, brown conidia with a single apical setula and 2–4 basal setulae, seceding rhexolytically from monoblastic, integrated, terminal conidiogenous cells. A key to Blastophragmia and its
morphologically similar genera is provided.
Qualitative Analysis of Cosmological Models in f(R)-Gravity
Authors: Avagyan R. M. , Chubaryan E. V. , Harutyunyan G. H. , Saharian A. A.
Published: April 2021

The spatially flat cosmological models are investigated within the framework of f(R)-gravity. An equivalent representation in the form of a scalar-tensor theory is discussed. For the general case of the f(R) function, the corresponding cosmological equations are presented in the form of a third order autonomous dynamical system. The qualitative analysis of the latter is given in the absence of nongravitational matter. Various special cases of the function F(R) are considered and the corresponding phase portraits are depicted. The possibility for the realization of a phase with accelerated expansion of the Universe is discussed.
Induced Cosmological Constant in Braneworlds with Compact Dimensions
Authors: Saharian A. A. , Sargsyan H. G.
Published: April 2021

We investigate the cosmological constant induced by quantum fluctuations of a bulk charged scalar field on a brane in background of locally anti-de Sitter spacetime with toroidally compact spatial dimensions. Along compact dimension quasiperiodicity conditions are imposed with general phases and, in addition, the presence of a constant gauge field is assumed. The latter gives rise to Aharonov-Bohm type effect on the characteristics of the scalar vacuum. The renormalization of the vacuum energy density on the brane is done by making use of the generalized zeta function technique. The behavior of the cosmological constant is studied as a function of the location of the brane, of the length of the compact dimensions and of the magnetic flux enclosed by the compact dimension. In particular, it is shown that the cosmological constant is a periodic function of the magnetic flux with the period equal to the flux quantum.
STUDYING THE SUBLIMATION OF CARBON DIOXIDE
Authors: NEVEROV Evgeniy N. , KOROTKIY Igor A. , KOROTKAYA Elena V. , RASSHCHEPKIN Aleksandr N.
Published: April 2021

Background: The utilization of dry ice in cooling and storage units requires adjusting the intensity of sublimation due to the requirements of prudently using CO2 to maintain preset thermal conditions. Aim: When designing a carbon dioxide cycle, it is essential to consider the influence of thermal gradients on the adsorption and desorption of carbon dioxide. Methods: tests were conducted to study the production and sublimation of carbon dioxide. The testes were aimed to define the temperature relation of the dry ice sublimation period, the density of pressed СО2, and the humidity of the environment and concentration. Results and Discussion: According to the obtained test data, there was a linear relationship between the sublimation intensity and the ambient air temperature in the specified conditions. The effect of moisture condensation on the sublimation rate appeared weaker than expected, for the amount of moisture on the surface of the specimens was insignificant. The heat exchange was intensified by the fall of hoarfrost and the related surface expansion. However, much moisture froze out without reaching the dry ice surface, and the formed layer of ice formed a heat insulation surface, and the sublimation under that layer was less intensive. The direct influence of sublimation came from the pressure at which a specific specimen was formed; however, 75 kN pressure was optimal. Conclusion: Despite higher weight losses during the storage, the difference in spent energy is more critical than 90 kN. The factor no less important was the carbon dioxide storage temperature. The maximal sublimation time of a 55 g cylinder formed at 75 kN and stored at – 80°С was 135 hours, much higher than at similar parameters but at -60°С. That said, the amount of energy spent on operating a low-temperature chamber was almost identical.
When everything is NOT awesome. Aktivisme, anklager og krisen som kontekst
Authors: Hoff-Clausen Elisabeth
Published: April 2021

In 2014 Greenpeace posted a short video appealing to Lego to end its cooperation with Royal Dutch Shell. The video raised an informal accusation and invited its audiences to support it, which more than one million people did. A reputational crisis was inflicted upon the two companies. The article discusses the rhetoric that enabled this activist success and asks to what extent the example set by Greenpeace might be worthy of imitation. It is argued that the mobilizing effect of the video cannot be explained merely by studying its spectacular form and content. The unusual effect must be seen in light of the climate crisis as an affective context that gave the emotional appeals of the video a strong resonance. It was the current climate crisis, implied in the video, which helped create a burning platform for change in the conduct of Lego and Shell
PRÁTICAS DE CUIDADO DE SI NAS CENAS INICIAIS NO BANQUETE DE PLATÃO.
Authors: Silva Felipe Gustavo
Published: April 2021

O presente trabalho trata de analisar duas cenas iniciais do diálogo de Platão, o Simpósio, envolvendo a chegada de Sócrates na casa de Agatão. A proposta é examinar como estas duas cenas sinalizam práticas de cuidado de si na antiguidade e, sobretudo, como antecipam questões que serão imprescindíveis para compreensão da leitura da obra como um todo. Ademais, trata-se de verificar como as práticas podem contribuir no processo do conhecimento através do cuidado de si.
CINEMA, ROMANCE E VIDA COTIDIANA
Authors: Miyamoto Hidemi Soares
Published: April 2021

O presente artigo tem como objetivo tecer uma análise da relação entre as formas artísticas romanescas e cinematográfica e a relação que ambas estabelecem com a representação da vida cotidiana. Para tanto, buscamos analisar a gênese dessas formas artísticas assim como tentamos compreender as peculiaridades de cada uma delas estabelecendo possíveis aproximações e diferenças entre ambas. Concomitante a essa análise procuramos apreender as categorias centrais que caracterizariam a vida cotidiana de acordo com o pensamento de György Lukács.
Il bambino che non va a scuola
Authors: Cozzi Giorgio , Barbi Egidio , Ventura Alessandro
Published: April 2021

Chronic school absenteeism is relatively common in childhood and adolescence. Most of the children with this behaviour remain at home with the awareness of their parents and complain physical symptoms as the reason for their behaviour. Paediatricians should be aware of the medical, familiar and social conditions more frequently associated with chronic school absenteeism and should learn the best way to approach affected children and their parents.
Il neonato con gli occhi socchiusi. La displasia ectodermica legata al gene TP63
Authors: Schierz Mandy , Corsello Giovanni
Published: April 2021

An Italian female newborn presented with cleft palate, erythroderma, desquamations, skin erosions, ankyloblepharon filiforme adnatum, broad nasal root, short philtrum, thin vermillion border, maxillary hypoplasia, microstomia, microglossia, cupped ears, hypoplasia of the distal phalange of left index, widely spaced nipples and polythelia. The hallmarks of ankyloblepharon-ectodermal dysplasia-clefting syndrome (or Hay-Wells syndrome) as well as persistent scalp erosions led to exclude more frequent skin disorders like congenital ichthyosiform erythroderma or epidermolysis bullosa and to diagnose Hay-Wells syndrome by genetic analysis. Target sequencing of the tumour protein p63 (TP63) gene revealed a novel heterozygous missense mutation I576T in exon 13 (c. 1727T>C) in the sterile alpha motive domain. The paper reports the clinical features, differential diagnoses and prognosis in TP63-related ectodermal dysplasia.
Un suono che inganna: quando sospettare il doppio arco aortico
Authors: Giannone Virginia , Goia Manuela , Bignamini Elisabetta
Published: April 2021

The article describes a case of a 10-month-old male infant presenting with respiratory distress, laryngotracheitis and double aortic arch (DAA). Tracheal compression by vascular structures in infants is uncommon and may be masked by nonspecific respiratory symptoms. DAA is the most common vascular ring. Doctors should think about a congenital vascular ring due to DAA in children with repeated episodes of laryngitis, hissing breath, cough and dyspnoea when other common aetiologies are excluded. A precise diagnosis can be made through the contrast-enhanced chest CT scan.
Teoria da resposta ao item aplicado ao inventário de vida diária de Katz numa amostra do Hospital Regional da Asa Norte – Brasília/DF
Authors: Albano Daniel Portela de Deus
Published: April 2021

Neste trabalho, será analisado o Inventário de Vida Diária de Katz (AVD KATZ) a partir da análise estatística da Teoria de Resposta ao Item (TRI) (q). Alguns estudos mostram que a demência é ligada a uma susceptibilidade genética e causa danos às atividades funcionais do indivíduo e, por isso, a importância da avaliação funcional do idoso. Para tanto, existem as Avaliações de Vida Diária que medem as funções de autonomia básica do indivíduo. A TRI consegue substituir, em partes, a Teoria Clássica dos Testes (TCT), pois avalia se o item realmente mede o traço latente que deveria medir. Os objetivos do estudo foram: analisar se os itens do AVD Katz realmente mediam autonomia; analisar as respostas de pacientes e verificar a discriminação e a dificuldade de cada item. A amostra total recolhida do Hospital Regional da Asa Norte (HRAN) de Brasília/DF, foi de 67 pacientes, sendo 42 (62,7%) mulheres e 25 (37,3%) homens. A partir das análises feitas com o software Xcalibre, pode-se notar que o teste AVD Katz tem uma boa sensibilidade em diferenciar pacientes com declínio cognitivo e início de processo demencial, de acordo com a pontuação do Clinical Dementia Rating (CDR). Além disso, essa proposta mostrou-se como um teste que mede a autonomia do paciente em relação às suas atividades de vida e seus itens têm boa correlação com o total do teste. O teste tem, atualmente, boa validade, porém, futuramente, com uma melhor educação e o advento da tecnologia ao alcance de todos, alguns itens poderão sofrer modificações.

Palavras-chave: Avaliação funcional. Demência. Teoria de resposta ao item (TRI). Inventário de atividades diárias.
Nanoestruturas em cosméticos: O que pensam estudantes de um curso técnico e as implicações da Ciência e Tecnologia nos produtos que utilizam nanoestruturas
Authors: Cantiliano Perez Letícia , Duso Leandro , Guadagnini Paulo Henrique , Lindemann Renata
Published: April 2021

O presente artigo tem como objetivo discutir as compreensões de estudantes de um curso técnico em estética, sobre a presença de nanoestruturas na composição dos cosméticos, na perspectiva de uma Alfabetização Científica e das implicações da Ciência e Tecnologia CT  nos produtos que utilizam as mesmas. A pesquisa, de caráter qualitativo, foi realizada em duas intervenções, as quais forneceram subsídios através de questionários, vídeos, artigos, relatórios e pesquisas para que surgisse um debate de ideias, com todas essas contribuições  a intenção foi de que as estudantes  construíssem um processo  de reflexão e debate sobre o consumo de nanocosméticos em seu cotidiano. A partir da análise dos materiais  coletados emergiram duas categorias: Visão ingênua sobre nanopartículas  em cosméticos e Implicações da CT nos produtos que utilizam nanopartículas. Na primeira foi observada uma visão simplista das estudantes frente a essa realidade, sem ao menos problematizar o uso desses nanocosméticos  e seus possíveis malefícios para a saude humana e para o meio ambiente, apresentando um conhecimento superficial sobre o tema, porém, a partir da intervenção tiveram a oportunidade de reorganizar, reelaborar e ressignificar suas compreensões sobre a presença da nanotecnologia em cosméticos. Em relação as implicações foi possível notar que a falta de conhecimentos  inter-relacionados da CT com a realidade, forma profissionais acríticos e alheios aos seus direitos e deveres como cidadãos. Conclui-se  a partir  do exposto que é necessário que  processos técnicos formativos considerem aspectos da Educação CTS em seus currículos, para a formação de indivíduos conscientes do seu papel na sociedade, com uma visão ampla dos reais problemas vivenciados nas suas profissões e as implicações destes na atualidade e ainda com conhecimento técnico para uma tomada de decisão consciente sobre o que lhes é ofertado.
Implementación de la figura del teletrabajo en el sector público de Costa Rica: avances y desafíos
Authors: Castillo José Alejandro
Published: April 2021

El presente artículo denominado “Implementación de la figura del Teletrabajo en el sector público de Costa Rica: avances y desafíos”, constituye un avance de investigación de mi tesis doctoral para acceder al grado de doctor en derecho por la Universidad Politécnica de Nicaragua, UPOLI. El objetivo de este artículo, es describir la experiencia de Costa Rica en las diferentes etapas del proceso implementación del teletrabajo, esto a raíz de una serie de entrevistas que se realizaron a actores claves de información y funcionarios públicos que participaron en este proceso a fin de identificar cuáles han sido las debilidades y desafíos que ha enfrentado el proceso. La discusión de este trabajo se centra en el marco teórico conceptual del informe regional “Desafíos para la implementación del teletrabajo en los sistemas jurídicos laborales de los países centroamericanos” elaborado en el marco de la estancia de investigación del autor investigación en la Universidad de San José, Alajuela, como becario del programa de intercambio académico regional, organizado por la Secretaría General del Sistema de Integración Centroamericana y auspiciado por la Cooperación Española entre los meses de mayo y junio del año dos mil dieciséis.
Emergency department use of monoclonal antibody therapy in high risk COVID positive patients
Authors: Barbera Andrew R. , Wilson Kayla , Melton III James D. , Blind Fred , Bhisitkul Donna M. , Degroot Diana , Faviere Donna , Fuell Joanne , Escowitz Hal , Regan Timothy J.
Published: April 2021

Background: There have been many perceived barriers to the implementation of the mass use of monoclonal antibody therapy following the Food and Drug Administration’s Emergency Use Authorization in November 2020. These barriers include identifying eligible patients, physical resources including trained staff members, space, and materials for the administration away from others to reduce transmission, and cost of the resources. However, Lakeland Regional Health was able to create a safe and efficient protocol to administer Bamlanivimab in the treatment of high risk COVID positive patients and initiate this proposed pathway within 24 hours of receipt of the first shipment of medication.Methods: Critical to the development and success of this protocol was a multi-disciplinary approach focused on identifying and utilizing preexisting resources to ensure safe and efficient administration of this treatment to as many eligible patients as possible. Another crucial aspect was the utilization of the emergency department providers for identifying high risk eligible patients and as a safe and effective treatment setting.Results: This article is intended to demonstrate a best practice pathway to identify and administer Bamlanivimab, or similar treatments, and will not discuss outcomes or efficacy of the medication. To date Lakeland Regional Health has successfully treated over 1,000 high risk COVID-19 positive patients within our community.Conclusions: By identifying and utilizing similar resources and pathways available at individual medical centers, it is possible to safely and efficiently treat high risk COVID positive patients with monoclonal antibody therapy on a large scale.
Individuals Higher in Eating Restraint Show Heightened Physiological Arousal to Food Images
Authors: Guinle Maria Isabel Barros , Yudien Mikhal A. , Norris Catherine J.
Published: April 2021

Individuals higher in eating restraint report feeling ambivalent (i.e., both positive and negative) about food, regardless of whether it is perceived to be unhealthy or healthy (Norris, Do, Close & Deswert, 2019). Given that ambivalence is thought to be a highly unpleasant, unstable, and arousing state, we sought in the current study to examine whether individuals higher in eating restraint show enhanced physiological arousal toward food (but not nonfood) images. Replicating our earlier findings (Norris et al., 2019), individuals higher in eating restraint exhibited more ambivalence towards both unhealthy and healthy food (but not nonfood) images than did those lower in eating restraint. Importantly, skin conductance reactivity (SCR) toward both unhealthy and healthy food images was greater for individuals higher in eating restraint than those lower in eating restraint; there were no group differences for nonfood images. Furthermore, eating restraint scores were positively correlated with SCR toward both unhealthy and healthy food images, suggesting that more extreme restraint is associated with stronger physiological arousal. Together, our results suggest that individuals higher in eating restraint experience more ambivalence and enhanced physiological arousal toward food images regardless of their perceived health value. Implications for treating individuals with eating disorders are discussed.
Assessing Community Adaptation Strategies to Floods in Flood-Prone Areas of Urban District, Zanzibar, Tanzania
Authors: Nassor Badriya S. , Makame Makame O.
Published: April 2021

Floods disasters around the world have increased for the last 20 years and affected billions of people. The same has been observed in Zanzibar, which resulted in severe impacts in many parts of the urban-west region and affected many people, threaten several lives and caused substantial economic losses. Therefore, this study intended to assess the community adaptation strategies to floods, the genesis of those strategies and the limiting factors for each adaptation strategies in flood-prone areas in the Urban District in Zanzibar, Tanzania. It involved 399 households. Data were collected using an interviewer-administered questionnaire for heads of the households to assess their adaptation strategies. The study discovered that the community has been employing different adaptation strategies to reduce the floods risk at pre, during and after floods. Before flooding is cemented the floor, while during flooding moved to another place and after flooding did the structural repairs of their houses and recommendations to the government on providing necessary support are delineated.
Het fenomeen ‘pedojagen’: toepassingsbereik van artikel 359a Sv, bezien in het licht van een mogelijke strafzaak tegen de (vermeende) pedoseksueel
Authors: Schmahl J.D. (Jessica) , Verbeek L.W. (Lune)
Published: April 2021

Het fenomeen ‘pedojagen’: toepassingsbereik van artikel 359a Sv, bezien in het licht van een mogelijke strafzaak tegen de (vermeende) pedoseksueel

‘Pedojagen’ is een groeiend fenomeen, zo blijkt uit recente incidenten. Strafvorderlijke autoriteiten dragen uit dat zij door pedojagers ontmaskerde vermeende pedoseksuelen niet zullen vervolgen. Het is de vraag of dit standpunt in de praktijk ook wordt nageleefd en of naleving altijd wenselijk is. De auteurs beargumenteren dat het OM tot vervolging moet kunnen overgaan wanneer door pedojagers een ‘evidente pedoseksueel’ wordt ontmaskerd. Onderzocht is welke ruimte het klassieke beoordelingskader van artikel 359a Sv (genuanceerd in HR 1 december 2020) aan de rechter biedt, dan wel zou moeten bieden, om consequenties te verbinden aan buitensporig optreden door pedojagers jegens de beschuldigde pedoseksueel.
Data-driven gameplay experience balancing
Authors: Mirza-Babaei Pejman
Published: April 2021

The overall aim of developing a game that is fun to play is often hard to achieve due to the complexities of the game development process. An accurate understanding of player behavior and their gameplay experiences can help identify and resolve any potential problem areas before release. In this keynote, I will use commercial case studies and academic research projects to provide a summary of my work in developing new evaluation methodologies, tools and data visualizations for games UX evaluation. I will discuss approaches and provide guidelines on how game developers and researchers can benefit from gameplay data to optimize player experience.
An Exploratory Study of Spirituality in German Enterprises
Authors: Alewell Dorothea , Moll Tobias
Published: April 2021

Spirituality at work is increasingly attracting attention in management research, especially in the Anglo-Saxon and Asian contexts. However, for the German context, we know little about spirituality at work from scientific research, and findings and results from other sources are broadly scattered. Using a mixed-methods approach, we collect first findings on employer’s perception of spirituality at work and specific HRM practices in German workplaces. We analyse daily newspapers and related best-practice publications and conduct a small-scale qualitative employer survey in Northern Germany. To structure the results, we propose three main impact perspectives on spirituality in the workplace (workforce diversity, employee needs, and employer capabilities) as well as different employer stances in dealing with these three perspectives, from faith-avoiding to faith-based (Miller & Ewest, 2015). In all three perspectives and stances, companies already implement different HR activities under different expectations and perceptions. Some German organisations already address the needs perspective by room-related tools, working time-related tools, food-related offers, and instruments that facilitate coordination and cooperation in multi-religious settings. Employer stances differ concerning religious and non-religious spirituality. While employers view nonreligious spirituality in the company as generally positive (faith-friendly), they are often sceptical of religious spirituality at work (faith-avoiding or faith-safe).
Tracing the Domestic Pigs in Africa
Authors: Weka Rebecca , Bwala Dauda , Adedeji Yinka , Ifende Isioma , Davou Anvou , Ogo Ndudim , Luka Pam
Published: April 2021

Pigs are vital to the economy and critical in meeting the ever increasing demand for livestock and livestock products in most parts of the world. Pig is one of the oldest domesticated animals, though their ancestory is still shrouded in controversy due to lack of sufficient archaeological and genetic information. However, most of the breeds are thought to have descended from the Eurasian Wild Boar (Sus scrofa). This chapter will therefore look at the African pig under the following headings: Introduction, origin of pigs – genetic and historical/archaeological evidences, pig breeds in Africa, economic importance of pig production in Africa, marketing of pigs in Africa, herd health management of pigs in Africa, and challenges affecting pig production in Africa.
Role of Humic Substances in Formation of Safety and Quality of Poultry Meat
Authors: Vladimirovna Simakova Inna , Alekseevich Vasiliev Alexey , Vyacheslavovich Korsakov Konstantin , Alexandrovna Sivokhina Lyudmila , Vasilievich Salautin Vladimir , Yurievna Gulyaeva Lyudmila , Olegovich Dmitriev Nikita
Published: April 2021

The purpose of this chapter was to study the influence of humic substances on the formation of the safety and quality of poultry meat. The high abilities of the natural and organic complex of humic acids “Reasil®HumicHealth” (produced in Russia, Saratov) to sorb and desorb five mycotoxins of compound feed (aflatoxin B1, ochratoxin, toxin T-2, zearalenone and fuminisin B1) were experimentally established. The hepatoprotective ability of humic acids was observed in experiments on broilers using rapeseed meal containing an increased amount of secondary plant metabolites that could cause liver damage. It was found out that the inclusion of humic acids in the amount of 1 and 1.5 g per 1 kg of feed to the main diet of broiler chickens has a more stable positive effect, both in terms of slaughter indicators (yield of semieviscerated carcasses and carcasses of complete evisceration), and in the production of the most valuable natural semi-finished products (breast, chicken legs) due to the intensive growth of muscle tissue. A clear improvement in the morpho-biochemical and immunological parameters of blood and micromorphometric characteristics of the organs of the immune system of poultry was noted with the use of different concentrations of humic acid salts. The use of the additive at the rate of 1 and 1.5 g per 1 kg of feed does not negatively affect the sensory indicators of finished culinary products.
Immune and Cell Cycle Checkpoint Inhibitors for Cancer Immunotherapy
Authors: M. Gordon Erlinda , L. Angel Nicole , T. Kim Ted , A. Brigham Don , P. Chawla Sant , L. Hall Frederick
Published: April 2021

The rational design of immunotherapeutic agents has advanced with a fundamental understanding that both innate and adaptive immunity play important roles in cancer surveillance and tumor destruction; given that oncogenesis occurs and cancer progresses through the growth of tumor cells with low immunogenicity in an increasingly immunosuppressive tumor microenvironment. Checkpoint inhibitors in the form of monoclonal antibodies that block cancer’s ability to deactivate and evade the immune system have been widely indicated for a variety of tumor types. Through targeting the biological mechanisms and pathways that cancer cells use to interact with and suppress the immune system, immunotherapeutic agents have achieved success in inhibiting tumor growth while eliciting lesser toxicities, compared to treatments with standard chemotherapy. Development of “precise” bio-active tumor-targeted gene vectors, biotechnologies, and reagents has also advanced. This chapter presents ongoing clinical research involving immune checkpoint inhibitors, while addressing the clinical potential for tumor-targeted gene blockade in combination with tumor-targeted cytokine delivery, in patients with advanced metastatic disease, providing strategic clinical approaches to precision cancer immunotherapy.
Impact of Climate Change on International Health Security: An Intersection of Complexity, Interdependence, and Urgency
Authors: Yellapu Vikas , Malan Samuel , Merkert Brandon , Kharecha Hetal , Alam Ambreen , P. Stawicki Stanislaw
Published: April 2021

Climate change (CC) can be defined as a long-term shift in global, continental, and/or local climate patterns. Although many equate CC to the rise in global temperatures, the issue is much more complicated and involves a large number of interconnected factors. Among some of the less discussed considerations of CC are its effects on a broad range of public health issues, including the emergence of novel infectious diseases, the encroachment of infectious disease vectors into previously unaffected geographic distributions, and crop failures resulting in threats of malnutrition and mass migration. This chapter will be devoted to key issues related to CC in the context of international health security (IHS).