bluuebunny/crossref_metadata_2025 huggingface dataset:
Aspectos identitários e culturais na formação dos nomes de lugares: um estudo sob a ótica da geografia cultural e humanista
Authors: Andrade Karylleila Santos
Published: March 2017

A Toponímia é a disciplina que estuda os topônimos, ou seja, os nomes de lugares e está ligada à lexicologia[1], ciência que pode ser definida como o estudo científico do léxico. O objetivo geral deste trabalho é identificar o papel da cultura e da identidade no processo de nomeação de lugares. Apoiar-nos-emos na abordagem da Geografia Cultural e Humanista para compreendermos, de forma mais aprofundada, a noção conceptual de lugar. A nomeação dos lugares relaciona-se diretamente com o modus vivendi dos grupos humanos, e os fatores culturais e de identidade são fundamentais nesse processo. Como percurso teórico-metodológico, utilizaremos os autores: Dick (1990, 1990a), XXXXX e Bastiani (2012), Holzer (2003) e Tuan (1979, 2012).

 

[1]A Lexicologia, ciência antiga, tem como objetivos básicos de estudo e análise a palavra, a categorização lexical e a estruturação do léxico. (BIDERMAN, 2001, p. 16)
City of Little Rock Neighborhood Alert Centers: An Assessment Report
Authors: Bacot Hunter , Diaz Christopher , Moore Bruce , Day Bryan
Published: March 2017

The City of Little Rock’s Neighborhood Alert Center program assessment focuses on understanding program functions, how these centers serve the respective neighborhoods, and the roles and responsibilities of neighborhood facilitators (program directors stationed at each location). A case study approach is used to provide a holistic, rigorous evaluation of the program. Though much has changed for these centers since the inception of the program, this assessment reveals that citizens appreciate the Neighborhood Alert Centers and their neighborhood facilitators. Assessment results show that these centers are key components to sustaining healthy, vibrant Little Rock neighborhoods. The project demonstrates the usefulness of an outside evaluation for providing recommendations to enhance a program and increase its capacity.
SEM-EDX Study of the Degradation Process of Two Xenograft Materials Used in Sinus Lift Procedures
Authors: Ramirez Fernandez Maria Piedad , Gehrke Sergio Alexander , Perez Albacete Martinez Carlos , Calvo Guirado Jose Luis , De Aza Piedad N.
Published: March 2017

Some studies have demonstrated that in vivo degradation processes are influenced by the material’s physico-chemical properties. The present study compares two hydroxyapatites manufactured on an industrial scale, deproteinized at low and high temperatures, and how physico-chemical properties can influence the mineral degradation process of material performance in bone biopsies retrieved 6 months after maxillary sinus augmentation. Residual biomaterial particles were examined by field scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) to determine the composition and degree of degradation of the bone graft substitute material. According to the EDX analysis, the Ca/P ratio significantly lowered in the residual biomaterial (1.08±0.32) compared to the initial composition (2.22±0.08) for the low-temperature sintered group, which also presented high porosity, low crystallinity, low density, a large surface area, and poor stability and a high resorption rate compared to the high-temperature sintered material. This demonstrates that variations in the physico-chemical properties of bone substitute material clearly influence the degradation process. Further studies are needed to determine whether the resorption of deproteinized bone particles proceeds slowly enough to allow sufficient time for bone maturation to occur.
Scapular Winging Caused by Combined Palsy of the Spinal Accessory Nerve and the Long Thoracic Nerve
Authors: Ago Kentaro , Matsumura Noboru , Iwamoto Takuji , Sato Kazuki , Nakamura Masaya , Matsumoto Morio
Published: March 2017

Case:

A 37-year-old man with scapular winging, caused by combined palsy of the spinal accessory nerve and the long thoracic nerve, was successfully treated with a pectoralis major transfer to substitute for the serratus anterior muscle, and with levator scapulae and rhomboid muscle transfers to substitute for the trapezius muscle.

Conclusion:

The serratus anterior paralysis was thought to have occurred secondary to traction of the long thoracic nerve by the unsupported scapula following the spinal accessory nerve palsy. Even with combined paralyses of the serratus anterior and trapezius muscles, combined muscle transfers that substitute for the paralyzed muscles can improve shoulder function.
CROSS-LANGUAGE TEXT CLASSIFICATION WITH CONVOLUTIONAL NEURAL NETWORKS FROM SCRATCH
Authors: Enweiji Musbah Zaid , Lehinevych Taras , Glybovets Аndrey
Published: March 2017

Cross language classification is an important task in multilingual learning, where documents in different languages often share the same set of categories. The main goal is to reduce the labeling cost of training classification model for each individual language. The novel approach by using Convolutional Neural Networks for multilingual language classification is proposed in this article. It learns representation of knowledge gained from languages. Moreover, current method works for new individual language, which was not used in training. The results of empirical study on large dataset of 21 languages demonstrate robustness and competitiveness of the presented approach.
DEVELOPMENT OF A COMPUTATIONAL EXPERIMENT FOR THE PARALLELING OF THE MODIFIED BRANCH AND BOUND METHOD FOR THE PROBLEM FOR THE APPOINTMENT OF PROCEDURES TO PATIENTS IN SANATORIUM
Authors: Danylchenko Anna , Kravchenko Svetlana
Published: March 2017

For the matching problem with vanishing arcs, an optimal algorithm based on the branch and bound method was developed to find the maximum matching in a bipartite graph [1].

The algorithm takes into account the limits of compatibility procedures. The calculated experiment is aimed at proving the feasibility of paralleling of the optimal algorithm for solving the problem of scheduling the reception of medical procedures by patients for use in the sanatoriums of Ukraine.

The experiment was carried out on computing platforms of different configurations with different computing power: a different number of processor cores, different amounts of memory, etc.

Estimated minimum time scheduling, received at the computer platform with the maximum number of PCs is involved. Estimated time scheduling algorithm paralleling by using modifications of the branch and bound method is directly proportional to the number of vertices of a bipartite graph (which is equal to the sum of the number of procedures and the number of patients), the number of assigned procedures and restrictions.
THE ANALYSIS OF INDICES OF CEREBRAL BLOOD CIRCULATION IN WOMEN-SMOKERS
Authors: Aponchuk Lyudmila , Shevchuk Tatiana
Published: March 2017

The results of rheoencephalography of female smokers 17–21 years old and control group were studied and analyzed. The aim of this work was to explain and analyze physiological features of smoking effect on functional changes of regional hemodynamics in smoking women.

The study of cerebral hemodynamics was carried out by the method of rheoencephalography (REG) – automated system of complex examination “Askold”, intended for automation of medical tasks processing with input of information in “online” regime (insertion of data directly from examined person). The recording of rheogram was carried out in front-mastoid branches that allowed register REG separately in both hemispheres of brain and determine the main amplitude-temporal characteristics of cerebral blood circulation and changes of vascular tone.

Analyzing the main indices of regional hemodynamics in female smokers, the statistically lower values of time of rheowave delay (Ra) were noted. There was also revealed a decrease of volumetric cerebral blood circulation and increase of resistant arteries tone. There were fixed the moderate asymmetry (from 15 to 25 %) of blood filling in vertebral-basilar vascular basin (basin of spinal and internal carotid arteries) and the signs of complicated venous outflow in both hemispheres.

Such changes of indices indicate the decrease of volumetric blood circulation of cerebral hemodynamics, striking volume of blood and increase of tone of distribution arteries that testify to the decrease of blood circulation in main vessels, and also smoking is a cause of hypoxia (oxygen deprivation) of cerebral cells as a result of decrease of blood inflow. In the women of control group all indices are within norm that testifies to the normal course of physiological processes in organism.
THE METHOD OF DETERMINATION OF THE SORPTION CAPACITY OF ACTIVATED CARBON BY GAS CHROMATOGRAPHY
Authors: Naumenko Ksenia , Frolova Natalia , Petrusha Oksana , Chepel Natalia
Published: March 2017

The article analyzes the possibility of gas chromatography use for determination of sorption capacity of adsorbents on the example of activated carbon BAC-A. The offered method provides the use of gas chromatograph with flame-ionizing detector and with nozzle geyser that is filled with studied adsorbent. At that the isotherms of absorption of substance are constructed by manifestation curve – desorption branch of substance peak on chromatogram.

As a result the isotherms of absorption of isoamylol and camphor on activated carbon were constructed and the values of specific sorption capacity for these substances were calculated.

This method allows receive fast and precisely the data about absorption characteristics of adsorbent and also adapt the conditions of the study using gas chromatography to the real conditions of adsorption of substances by studied adsorbent (temperature, adsorbent concentration in vapor phase and so on).
Az oktatáspolitika műveltségképe
Authors: Polónyi István
Published: March 2017

A tanulmány a hazai felsőoktatás-politika műveltségképének alakulását vizsgálja a rendszerváltástól napjainkig. Elemzi a posztindusztriális társadalom és gazdaság sajátosságait, a posztindusztriális korszak oktatásának jellemzőit, illetve az egyetem értelmiségképző szerepének átalakulását a középkori egyetemtől a huboldti egyetemen át a szolgáltató egyetemig. Végezetül a tanulmány bemutatja a magyar felsőoktatási törvényekben és a kormányzat felsőoktatási stratégiájában az értelmiség, az értelmiség-képzés, a műveltség és a szakember-képzés szavak előfordulásának gyakoriságát, és kontextusát. A törvények és a koncepció szóhasználata tükrözik a gazdasági és politikai mozgásokat. A rendszerváltást követően elmozdul a társadalmi, gazdasági szerkezet a posztindusztrializáció felé. A 2010. évi kormányváltást követően egy „visszaiparosítási” politika tapasztalható, amely a szakértelmiségi műveltségkép felé történő visszamozdulást eredményezett.
Fogyatékossággal élő személyek munkaerő-piaci (re)integrációjának aktuális kérdései a felnőttképzés területén II.
Authors: Hangya Dóra
Published: March 2017

A tanulmány első része, elméleti bevezetője a Neveléstudomány folyóirat előző 2016/4. számában jelent meg. A tanulmány második részében az „Esély(egyenlőség)-Részvétel-Lehetőség Fogyatékossággal élő személyek munkaerő-piaci (re)integrációjának aktuális kérdései a felnőttképzés területén” című kutatásom eredményeit mutatom be. Célom volt megismerni a fogyatékossággal élő személyek foglalkozási rehabilitációjának egy fontos területét, az iskolarendszeren kívüli felnőttképzési intézmények működését. Kiemelten vizsgáltam a fogyatékossággal élő felnőttek képzésekhez történő akadálymentes hozzáférésének lehetőségeit, figyelembe véve az iskolarendszeren kívüli felnőttképzéshez kapcsolódó jogszabályi előírásokat. A kutatás hiánypótló információk forrásaként szolgál a fogyatékossággal élő személyek képzésben történő részvételére vonatkozóan, mind a felnőttképzési, mind pedig az érintett, fogyatékossággal élő személyek oldaláról. A kutatás lefolytatását a „Közösen a Jövő Munkahelyeiért” Alapítvány támogatta.
Gyermekmunka 1945 előtt
Authors: Somogyvári Lajos
Published: March 2017

Deáky Zita (2015): Gyermekek és serdülők munkája Magyarországon a 19. századtól a második világháborúig. Gondolat Kiadó, Budapest.
Influences of physical and structural parameters on vibration modes for large-scale rotating wind turbine blades
Authors: Zhang Jianping , Shi Fengfeng , Wu Helen , Ren Jianxing , Wang Hao , Hu Danmei
Published: March 2017

For large-scale offshore wind turbine blades, ANSYS and UG were respectively used to complete the solid modeling and the calculation of vibration modes, and the influences of the rotating speed on each order vibration mode and their main reasons were analyzed. Furthermore, the effects of material categories, the deviations of physical parameters in the process of material manufacture and structural parameters on the natural frequencies of rotating blades were respectively compared. Numerical results show that the dynamic stiffening effect of rotating blades is obvious, and the stress stiffness and the geometric stiffness play a dominant role on the natural frequencies from the first to the sixth order and from the seventh to the tenth order respectively. The influences of material categories on natural frequencies of the blades are significantly higher than those of physical parameter deviations and chord length changes. The effects of the equal amplitude increase of elasticity modulus or the chord length and the equal amplitude decrease of density on the tenth order frequency for the torsional vibration are less than those of them on the first nine orders' frequencies for the shimmy and flapping vibration, making that the increase amplitude of the blade natural frequencies first increases and then decreases with the increase of the order number. In addition, the results in this work can provide technical references for the optimization design and the further analysis of vibration characteristics of wind turbine blades.
Numerical simulation and experimental research of spectral noise characteristics for the four-wheel landing gear
Authors: Li Ting , Zhang Jin-hua , Wang Bao-zeng , Xue Tao
Published: March 2017

Numerical simulation and wind tunnel experiment were conducted for flow field and flow noise characteristics of four-wheel landing gear. Under the landing speed, large eddy simulation method was applied to simulate the unsteady turbulent flow field around the landing gear. In addition, vortex-acoustic theory was also employed to compute the intensity and position of sound source, and integral method of FW-H equation was used to solve the sound field generated from different components and their combinations, analyze the noise generation mechanism, spectral characteristics and far-field directivity. Meanwhile, the contribution of each component to the total noise was assessed. The aerodynamic acoustic experiment was conducted for landing gear in the wind tunnel, and a microphone was applied to measure and obtain the spectral characteristics of noise, which was compared with the numerical computation result. As shown from the result, a good agreement was found between the experimental and numerical results. Besides, it was shown from the simulation result that small parts ignored in the computational sound field played a greater impact on prediction result of noise, especially high-frequency noise. As shown from landing gear vorticity and sound pressure distribution, sound source was mainly distributed in the solid surface of various components for the landing gear. Additionally, sound source was also occurred in the vortex shedding positions behind each component. Greater energy and density of the sound source were found in the gap formed between tire and bogie and in the pillar stairs. The tire noise showed maximum contribution to the total noise, followed by the bogie noise, while the pillar noise was minimal. The total noise spectrum was closest to the tire noise spectrum.
Numerical investigation on the propulsive performance of flexible flapping fins using CFD/CSD method
Authors: Liu Long , Ang Haisong
Published: March 2017

A FSI (fluid-structure interaction) numerical simulation was performed to investigate the flow field around a flexible flapping fin using an in-house developed CFD/CSD solver. The three-dimensional fluid-structure interaction of the flapping locomotion was achieved by loosely coupling preconditioned Unsteady Reynolds-Averaged Navier-Stokes (URANS) solutions and non-linear co-rotational structural solutions. The CSD solver was developed specifically for high flexible flapping fins by considering the large geometric nonlinear characteristics. Validation of benchmark tests illustrated the high-fidelity of the developed methodology. Then effect of flexural angles, flexural amplitude and flapping frequency in terms of Strouhal number were evaluated. Results demonstrated that different flexural angles will present different flow fields, and thus significantly varied thrust generation and pressure distribution. The thrust does not increase monotonically with flexural angles. The thrust is also found to increase with increasing Strouhal number while propulsive efficiency peaks within the range of 0.2 <St< 0.4, which lies in the middle of the range observed in nature. The appropriate combination of flexibility and Strouhal number illustrates higher efficiency and gives instruction for further design of flexible flapping fins.
Instability behaviors of a cylinder array under both increasing and decreasing flow velocities
Authors: Zhang Xu , Jiang Bin , Xiao Xiaoming
Published: March 2017

This study aimed to investigate the effects of increasing and decreasing crossflow velocities on the fluid-elastic instability behaviors of cylinder arrays. The responses of an elastically mounted cylinder in a rigid normal square cylinder array in a water tunnel subjected to crossflow were tested. The responses were simultaneously obtained from both in-line and transverse vibrations. Results show that the responses under increasing freestream velocity differ from those under decreasing freestream velocity. Under decreasing freestream velocity, fluid-elastic instability was accompanied by nonlinear hysteresis, and the cylinder exhibiting this instability can remain in this state for a certain range of flow velocities. Added mass coefficients were also obtained. Two criteria for fluid-elastic instability were applied.
Optimization of vibration reduction of the rubber floating-slab tracks
Authors: Jin Hao , Zhou Shunhua , Liu Weining
Published: March 2017

The floating-slab track is one of the best methods to reduce the vibration from the underground railway. In this paper, the rubber floating-slab track was studied. The train-track model coupled with the track-tunnel-surrounding soil model was built, which was verified by the results of the in-site test. Through this model, the quality of the rubber floating-slab track was optimized by the multi-island genetic algorithm. The optimized Z vibration level was reduced by 4.92 dB with the density of the floating slab 2306 kg/m3, the Young’s modulus of the floating slab 3.21×1010 N/m2, the density of the rubber bearing 730 kg/m3 and the Young’s modulus of the rubber bearing 9.55×108 N/m2.
Dynamics characteristics of a rotary table motorized spindle with externally pressurized air bearings
Authors: Xu Chundong , Jiang Shuyun
Published: March 2017

The face grinding process depends on high-precision rotary table spindle with a large axial load capacity. This paper develops an ultra-precision rotary table spindle with externally pressurized air bearings consisting of a double-pad thrust bearing and a journal bearing; a vacuum clamp system is designed to locate and hold the workpiece. The dynamic model for the rotor-bearing system has been established by using the Reynolds equation and the rigid-body dynamic theory considering five degrees of freedom (DOF). The effects of static and dynamic behaviors of the spindle with the bearing’s key parameters are analyzed systematically. Finally, an experiment study is conducted to verify the theoretical model.
Experimental study of vortex-induced vibration for drilling risers under uniform flow current
Authors: Mao Liangjie , Liu Qingyou , Zhou Shouwei , Long Zugang
Published: March 2017

An experiment was conducted in a deep water basin to investigate the vortex-induced vibration mechanism of a drilling riser. Various measurements were obtained by the fiber Bragg grating strain sensors, and data was analyzed by modal analysis method. Results show that the vibration mode of the drilling riser increases with the increasing flow velocity, and the vibration amplitude in the CF direction is larger than that in the IL direction. The vibrations in the CF and IL directions interact and mutually affect each other. The vibration mode in the IL direction is usually larger than that in the CF direction as the dominant vibration frequency is twice of that in the CF direction. Higher stresses may occur rather in the IL direction than in the CF direction. Hence, fatigue induced by the IL direction should also be taken into consideration when analyzing the fatigue life of a drilling riser. The three-time harmonic appears, and the phenomenon becomes more obvious as the flow velocity increased for the effect of the “2T” wake mode under the experiment condition. Displacement trajectories are significantly influenced by dominant vibration frequency and phase angle between the CF and IL directions. Crescent shapes, figure-eight, and inclined figure-eight are appeared in the experiment with the increasing flow velocity.
Torque and thermal characteristics analysis of a fluid damping based multi-degree-of-freedom motor
Authors: Li Zheng , Nie Wei , Zhi Ruodong , Xue Zengtao , Wang Qunjing
Published: March 2017

This paper presents a novel fluid damping based hybrid drive multi-degrees-of-freedom permanent magnet motor. The structure and working principle of the motor is introduced. The torque features are analyzed using both finite element method and analytical method. Based on the thermal safety and thermal stability in the practical design of this motor, the thermal characteristics with heat sources are calculated and simulated. By using FEA software to model the heating status when the motor works under rated operation and high overload current conditions, the temperature contours within the motor structure can be obtained. The fluid and modal analysis are also conducted with numerical simulation. The research results validate the reasonable structure design of this motor and can be the reference of structure optimization and performance improvement indicators for this kind of motors.
Bursting oscillation and bifurcation mechanism in fractional-order Brusselator with two different time scales
Authors: Chen Jufeng , Li Xianghong , Hou Jingyu , Zuo Dawei
Published: March 2017

The integer-order and fractional-order Brusselators with two different time scales are studied. The double-Hopf bursting oscillation is observed in Brusselator with periodic perturbation under some parameter conditions. Based on slow-fast analysis and bifurcation theory, the generation mechanism of periodic bursting oscillation is presented in detail. Further investigation finds that the perturbation amplitude plays an important role on bursting oscillation. With the decrease of perturbation amplitude, the attractor types will be changed, so that the bi-stability evolves into single stability. It causes that four times transitions between spiking and quiescent states may decrease to twice one, and the spiking state disappears finally. Furthermore, the influence of the fractional order on bursting behavior is investigated, and the bifurcation diagram with respect to fractional order and slow variable is given. With the decrease of fractional order, the two Hopf bifurcation points may approach each other gradually, overlap and disappear finally, which results into the transition from periodic bursting oscillation with different frequency ingredients into generally periodic oscillation with single frequency.
Retrospective Analysis of Patients with Genitourinary Fistula
Authors: Başaranoğlu Serdar , Deregözü Ayşegül , Hatırnaz Şafak , Şahin Coşkun , Kadanalı Sedat
Published: March 2017

Objective: To present the outcomes of patients treated at a tertiary center for a diagnosis of genitourinary fistula secondary to gynecological and obstetric etiologies.Study Design: In this retrospective study, analysis was made of 18 patients with a diagnosis of genitourinary fistula in a tertiary center between January 2006 and June 2016. Patient data were taken from the archives and patient histories. A record was made of examinations, diagnostic methods such as cystoscopy and fistulography and appropriate medical treatments, demographic data, intraoperative and post-operative complications, duration of hospital stay, surgical operations and types, diameter and location of fistulas.Results: Of the 18 cases, 14 were secondary to obstetric trauma. In 10 of these 14 cases, fistula had developed after difficult vaginal delivery and in four cases, after caesarean section. Four of the 18 cases were secondary to gynecological surgeries, namely hysterectomy and cystocele repairs. Vesicovaginal fistulas were repaired transvaginally while vesicouterine fistulas and bilateral ureterovaginal fistulas were repaired transabdominally. The mean hospital stay was 3.8±1.5 days (2-7 days). Patients were followed up closely in the first 3 months and recurrence developed in only one case.Conclusion: Fistulas secondary to gynecological procedures are uncommon while fistulas secondary to inadequate perineal care, insufficient labor monitoring and difficulties in vaginal delivery techniques are more prevalent in Turkey. Thorough evaluation, using all diagnostic tools for complete diagnosis, understanding the pathophysiology and choosing the best surgical procedure are mandatory to obtain good outcomes after the surgical
Hydroxypyridinone Derivatives: A Fascinating Class of Chelators with Therapeutic Applications - An Update
Authors: Chaves Sílvia , Piemontese Luca , Hiremathad Asha , Santos M. Amélia
Published: March 2017

Hydroxypyridinones (HPs) are a family of N-heterocyclic metal chelators, which
have been an attractive target in the development of a variety of new pharmaceutical drugs,
due to their high metal chelating efficacy/specificity and easy derivatization to tune the desired
biological properties. In fact, along the last decades, hydroxypyridinone derivatives, but
mostly 3-hydroxy-4-pyridinone (3,4-HP), have been intensively used in drug design, following
either a multitarget approach, in which one chelating unity is extrafunctionalized (hybridized)
to enable the interaction with other important specific biological sites, or a polydenticity
approach, in which more than one chelating moiety is conveniently attached to one scaffold,
to increase the metal chelating efficacy. This review represents an update of the most recent
publications (2014-2016) in mono-HP hybrids, namely as potential anti-Alzheimer's drugs,
inhibitors of metalloenzymes and anti-microbials, and also polychelating compounds (poly-
HP), in view of potential application, such as anti-microbial/biostatic agents, luminescent biosensors
or diagnostic agents.
Effects of PHA-665752 and Cetuximab Combination Treatment on In Vitro and Murine Xenograft Growth of Human Colorectal Cancer Cells with KRAS or BRAF Mutations
Authors: Jia Yi-Tao , Yang Dong-hai , Zhao Zhaolong , Bi Xiao-Hui , Han Wei-Hua , Feng Bo , Zhi Jie , Gu Bin , Duan Zhihui , Wu Jian-Hua , Ju Ying-Chao , Wang Ming-Xia , Li Zhong-Xin
Published: March 2017

Background:

It remains unknown whether blockade of c-Met signaling and epidermal
growth factor receptor signaling is effective in suppressing the growth of human colorectal cancer
(CRC) cells. In this study, we investigated the effects of the c-Met inhibitor PHA-665752 alone and
in combination with cetuximab on the growth of human CRC cells in vitro and in mouse xenografts.

Methods:

Human CRC cell lines (Caco2, HCT-116, and HT-29) and mice bearing HCT-116
xenografts were treated with cetuximab in the absence or presence of PHA-665752. Cell viability
and apoptosis were examined using the MTT and TUNEL assays, respectively. Vimentin was measured
by immunohistochemistry as a marker for epithelial-to-mesenchymal transition. Western blotting
was used to determine signaling protein expression levels.

Results:

The MTT assay showed that the growth of Caco2, HCT-116, and HT-29 cells was inhibited by
PHA-665752 in a dose-dependent manner, but only Caco2 cell growth was suppressed by cetuximab.
Combination treatment with PHA-665752 and cetuximab inhibited the proliferation of Caco2
cells and RAS mutant CRC cell lines. However, relative to the PHA-665752-alone treatment group,
HT-29 cells with a BRAF mutation showed no noticeable effect. The mean tumor volume in mice
treated with cetuximab in combination with PHA-665752 was significantly smaller than that in the
mice treated with only cetuximab (P = 0.033) or PHA-665752 (P < 0.01). Similarly, the expression of
vimentin in the mice treated with PHA-665752 in combination with cetuximab was significantly lower
than that in the mice treated with cetuximab or PHA-665752 alone (P < 0.05 in each case). TUNEL assays
revealed that treatment with PHA-665752 in combination with cetuximab markedly increased
CRC cell apoptosis. Western blotting analysis of signaling protein expression showed that PHA-
665752 inhibited Met phosphorylation (P < 0.05). In addition, treatment with cetuximab alone or in
combination with PHA-665752 effectively inhibited EGFR phosphorylation (P < 0.05).

Conclusion:

Combination treatment with PHA-665752 and cetuximab suppressed in vitro and in
vivo CRC cell growth more than treatment with either agent alone did.
Distorsi citra tubuh, perilaku makan, dan fad diets pada remaja putri di Yogyakarta
Authors: Sulistyan Atika , Huriyati Emy , Hastuti Janatin
Published: March 2017

Background: Vast changing environment and culture including mass media which commonly shows models with a very slim body may cause teenage girls feel fatty and not confident despite their normal body weight. This misperception may influence eating behavior and encourage them to lose weight by involving in some instant diets, for example, fad diets.Objective: To identify relationships between body image distortion, eating behavior, and fad diets among female adolescents in Yogyakarta.Method: This study was a cross-sectional study on 123 school girls at SMAN 8 Yogyakarta who have normal body mass index (BMI) according to WHO category. Body image distortion and eating behavior were evaluated using the Body Image Assesment-Body Dimension (BIAS-BD), and the Eating Attitude Test (EAT)-26, respectively. Fad diets were assessed using a questionnaire adapted from Hana (10) and Rafiqa (11). The hypotheses were tested using chi-square test and Spearman’s correlations.Results: As many as 105 girls (85.4%) showed body image distortion and 15 girls (12.2%) were at risks for having disordered eating behavior. Among 51 girls (42.5%) who experienced or tried to lose weight, 47 girls (92.2%) were practicing fad diets. There was no significant association between body image distortion and disordered eating behavior, nor between body image distortion and fad diets. However, disordered eating behavior was significantly associated with fad diets with OR = 7,077 (p<0.05).Conclusion: There was a significant relationship (p<0.05) between disordered eating behavior and fad diets, however, no significant association was found between body image distortion and disordered eating behavior, and between body image distortion and fad diets among female adolescents in Yogyakarta.
Potensi glukomanan pada tepung porang sebagai agen anti-obesitas pada tikus dengan induksi diet tinggi lemak
Authors: Nissa Choirun , Madjid Indah Juliana
Published: March 2017

Background: Epidemiological studies indicate that the global prevalence of obesity has increased. Glucomannan is a water-soluble, non-starch polysaccharide, known as soluble fiber. Glucomannan has the ability to lower blood cholesterol levels and blood glucose levels, weight loss and affects the activity of intestinal and immune system function.Objective: The purpose of this study was to determine the effect of glucomannan derived from konjac flour as antiobesity agent on body weight and food intake in rats induced by high-fat diet.Method: Research was conducted in the Pharmacology Laboratory, Faculty of Medicine, University of Brawijaya. This study uses a true experimental research design. Animals were divided into six groups, normal group, normal + konjac flour, obese group, obese group + konjac flour 100 mg/kg body weight, obese group + konjac flour 200 mg/kg body weight, obese group + konjac flour 400 mg/kg.Results: Based on One-way ANOVA test, there is a significant difference (p: 0.000) on body weight after konjac flour treatment in all groups. Based on the Kruskal-Wallis test, there is a difference in food intake in various groups (p = 0.000).Conclusion: It can be concluded that glucomannan derived from konjac flour can decrease body weight and food intake in rats induced by high-fat diet.
Asupan lemak jenuh dan serat pada remaja obesitas kaitannya dengan sindrom metabolik
Authors: Widyastuti Nurmasari , Dieny Fillah Fithra , Fitranti Deny Yudi
Published: March 2017

Background: There is an emerging global increase of metabolic syndrome prevalence due to increasing of obesity. Obesity and metabolic syndrome beginning in childhood progressing into adulthood.  Dietary saturated fat and fiber intake play a role in etiology in obesity.Objective: This study was to examine the associations between dietary saturated fat intake, fiber intake and components of metabolic syndrome among obese adolescents.Method: A cross-sectional study was conducted to 57 obese students aged 13-15 years old of SMP Nasima and SMP Kesatrian 2 Semarang, based on body mass index for ages. Subjects of this study were collected consecutively. Data were collected through waist circumference and blood pressure measurements, fasting biochemical serum analysis and dietary intake assessment.  Rank Spearman and Pearson correlation test was used to examine the associations between of dietary saturated fat and fiber intake to components of metabolic syndrome.Results: There were 46 subjects (80,7 %) had metabolic syndrome and 11 subjects (19,3 %) had the pre-metabolic syndrome. There was no association between dietary saturated fat intake and waist circumference, HDL cholesterol, triglyceride, fasting blood glucose levels and blood pressure. Fiber intake was negatively associated with blood triglyceride levels (r = -0.340; p = 0.01).Conclusion: There was no association between dietary saturated fat intake and components of metabolic syndrome. There was an association between dietary fiber intake with blood triglyceride levels. Dietary fiber intake has an important role in lipid metabolism.
Pengaruh ekstrak teh hijau (Camellia sinensis) terhadap kadar malondialdehid (MDA) plasma dan kekuatan genggam tangan lanjut usia
Authors: Nofiartika Fera , Susetyowati Susetyowati , Pramantara I Dewa Putu , Lestari Lily Arsanti
Published: March 2017

Background: Prevalence of Indonesian elderly has now reached 7%, which is considerably high. Physical performance is an important health status indicator in elderly. Declining of physical performance such as hand grip strength in elderly is related to oxidative stress. Furthermore, oxidative stress plays an important role on the decreasing of skeletal muscle function. Plasma malondialdehyde (MDA) is a lipid peroxidation residue that is often used as an oxidative stress biomarker. Meanwhile, tea is the most widely drunk beverage after water. Green tea contains antioxidants that can reduce the damages caused by oxidative stress. Objective: To assess the effect of green tea extract (GTE) on plasma malondialdehyde level and hand grip strength of elderly.Method: This was a double-blind experimental with pre-post test and control group. Fifty-seven elderly people from Balai Pelayanan Social Tresna Wredha (BPSTW) Abiyoso and Budi Luhur who met inclusion and exclusion criteria were divided into 2 groups. During 30 days, the first group was given 2 capsules of GTE a day (±168 mg catechin and 95 mg Epigallocatechin gallate (EGCG) and the second group was given a placebo. MDA was measured by thiobarbituric acid  (TBA)method and hand grip strength was measured by handgrip hand grip dynamometer. Results: There was a significant decreasing MDA (p<0,05) in the GTE group, but not in the placebo group. There was also increasing handgrip strength in the GTE group but not in the placebo group. Conclusion: Green tea extract can prevent increasing MDA and declining physical handgrip strength in elderly.
Tingkat kecemasan, asupan makan, dan status gizi pada lansia di Kota Yogyakarta
Authors: Rohmawati Ninna , Asdie Ahmad Husein , Susetyowati Susetyowati
Published: March 2017

Background: Psychological factors such as anxiety have significant contributions in determining dietary intake and nutritional status of elderly. Prevalence of malnutrition in elderly has achieved significant level.Objective: To determine the correlation between anxiety level with dietary intake and nutritional status of elderly in Yogyakarta municipality.Method: This research was observational with cross sectional design. Subjects were elderly in Yogyakarta municipality who fulfilled inclusion criteria. Research subjects consisted of 214 people. Anxiety level was measured with trait-manifest anxiety scale (T-MAS) form, dietary intake with semi-quantitative food frequency questionnaire (SQFFQ) method, and nutritional status was determined based on body mass arm span (BMA). Data were analyzed with Chi-Square test and multiple logistic regression.Results: A percentage of 26.2% subjects had moderate anxiety level. Most dominant factors that influenced anxiety level was sex (OR=3.37). Bivariate analysis showed a significant correlation between anxiety level and nutritional status (p<0.05), subjects with moderate anxiety level were more likely to have higher nutritional status (OR=3.54) and lower nutritional status (OR=2.29). Significant correlation was found between moderate anxiety level with excessive dietary intake (p<0.001; OR=6.22). Significant correlation was also found between dietary intake with nutritional status (p<0.05), subjects with excessive dietary intake were more likely to have higher nutritional status (OR=6.15).Conclusion: Significant correlation was found between anxiety level and nutritional status. Significant correlation was also found between anxiety level and dietary intake, and significant correlation was found between dietary intake and nutritional status.
Pemberian kombinasi probiotik dan zinc terhadap perubahan kadar hemoglobin, albumin, dan indeks massa tubuh pada pasien tuberkulosis paru
Authors: Arifah Meika Rahmawati , Darmono Darmono , Sofro Muchlis Achsan Udji
Published: March 2017

Background: TB patients are generally the most productive age group and suffer from chronic energy deficiency. Therefore, patients with TB requires a combination of chemotherapy and supplementary feeding as probiotics and zinc to boost the immune response and nutritional status.Objective: To analyze the effect of a combined of probiotics and zinc on the changes of hemoglobin, albumin level, and BMI.Method: This study is a quasi-experimental, randomized design with pre-post test control group involving 52 respondents. They were divided into two groups. The treatment group was given a combination of 1 capsule of probiotics (2 billion probiotics) and zinc 20 mg per day for 28 days. The analysis is paired t-test, independent t-test, Mann-Whitney, Pearson, Spearman, Covariance.Results: There was an increase in hemoglobin (p=0.01), albumin (p=0.01) and BMI (p=0.01). There is no difference between the two groups in the levels of hemoglobin parameter (p=0.21) and BMI (p=0.12), whereas there is a difference parameter albumin levels (p=0.01). The effectiveness of interventions is 4% for hemoglobin levels, 16% to albumin, and 1% for IMT.Conclusion: Probiotics and zinc for 28 days in patients with pulmonary tuberculosis may increase levels of hemoglobin, albumin, and BMI, but there is no significant difference in the changes of BMI. The most powerful influence of intervention effectiveness is on albumin.
PRESENTACIÓN.
Authors: Bolom Ton Fausto
Published: March 2017

Los autores de los cuatro artículos que dan inicio a este número de la revista Pueblos y fronteras digital se ocupan de temas contrastantes del estado de Chiapas y del sureste mexicano. En el primero, "Pueblo trágico: gubernamentalidad neoliberal y multicultural en el sureste mexicano", Sandra Cañas muestra la forma en que un programa gubernamental como el de "Pueblos mágicos" aboga por la inclusión multicultural pero desde una lógica mercantilista en la que sectores de población, particularmente indígenas, permanecen excluidos, sin poder de decisión, obteniendo minúsculos y muy cuestionables beneficios. ...
IMPACTO ECONÓMICO Y SOCIAL DEL FERROCARRIL PANAMERICANO EN LA REGIÓN DE TONALÁ EN EL SIGLO XX
Authors: Molina Pérez Valente
Published: March 2017

Este artículo analiza las transformaciones ocurridas en la región de Tonalá, Chiapas, durante el siglo xx, asociadas con la presencia del ferrocarril, fundamentalmente en las dimensiones social y económica. Se revisa la significación de este medio de comunicación terrestre cuyo impacto en esa localidad fue disminuyendo durante el siglo pasado, por cambios en varios órdenes de la vida social, política y económica del estado.
“Tercer Cine Cordobés”: formas de la representación del otro
Authors: Triquell Ximena
Published: March 2017

El presente artículo recupera la tipología propuesta por Fernando Solanas y Octavio Getino a finales de la década del sesenta que define las categorías de Primer, Segundo y Tercer Cine. El trabajo revisa la actualidad de estos conceptos y los recupera para abordar el llamado Nuevo Cine Cordobés, específicamente en lo que hace a la representación de los sectores populares. Para ello se consideran las películas De Caravana (Ruiz, 2011), Yatasto (Paralluelo, 2012) y Guachos de la calle (Schmucler, 2015).
Da Portela para a Mangueira: um passeio pela mediação nos documentários O mistério do samba e O samba que mora em mim
Authors: Carréra Campos Leal Guilherme
Published: March 2017

O presente artigo tem como premissa apresentar dados sobre a produção documentária brasileira focada na temática do samba (a partir da base da Agência Nacional do Cinema, do Portal Filme B e da Cinemateca Brasileira), a fim de analisar particularmente dois documentários de longa-metragem interessados na representação desse universo no cinema. O mistério do samba (Carolina Jabor e Lula Buarque de Hollanda, 2008) e O samba que mora em mim (Georgia Guerra-Peixe, 2012) enfocam personagens e lugares historicamente associados à discussão: a Velha Guarda da Portela, no subúrbio de Oswaldo Cruz, e os moradores do Morro da Mangueira, respectivamente. Questões sobre a relação estabelecida entre quem filma e quem é filmado são o cerne deste artigo, cujo objetivo é pôr luz sobre o debate que circunda a realização de documentários sobre samba no Brasil.
“Eu não quero ter um mundo de uma cor só”: trajetória, autoria e estilo nos filmes do cineasta Flora Gomes
Authors: Oliveira Jusciele Conceição Almeida de
Published: March 2017

O trabalho parte de uma revisão teórica do conceito de autor e da “ideia de autoria”, tal como foi transposta pelas instâncias da teoria acadêmica, crítica cultural, artística e cinematográfica, por alguns estudiosos no campo das artes e dos cinemas africanos, para, em seguida, examinar os modos como ela é assumida, negociada, e afirmada e/ou refutada nos filmes do bissau-guineense Flora Gomes, ressaltando seu estilo e algumas marcas autorais iniciais. Informa-se também que o presente texto faz parte do projeto de doutorado, que se encontra em fase de escrita da tese.
Sobre a colonialidade do pensamento em imagens e a reinvenção da negritude no Fespaco: maior festival de cinema africano
Authors: De Oliveira Maíra Zenun
Published: March 2017

Desde 1973, acontece em Burkina Faso, África Ocidental, o Festival Pan-Africano de Cinema e Televisão de Ouagadougou (FESPACO). Trata-se do maior e mais antigo evento audiovisual que ocorre em África, incluindo a exposição, premiação e discussão de filmes produzidos em todo o continente africano e seus territórios diaspóricos. Tal evento-ritual foi concebido por líderes burkinabés da revolução anticolonial dos anos 1960, que perceberam no cinema uma forma de luta e libertação. A manutenção de um festival tão grande se justifica, segundo organizadores do FESPACO, em função da enorme necessidade que os países africanos sentem de desconstrução das imagens e memórias produzidas pelo sistema-mundo colonial capitalista sobre a África e suas populações. Imaginário perpetrado diante do perverso e sólido legado afetivo e sensorial criado pelo sistema colonial. Portanto, neste artigo, apresento a discussão que venho desenvolvendo desde 2014, como projeto de pesquisa de doutorado em Sociologia do Cinema, na qual investigo o papel do FESPACO no processo de fortalecimento de um cinema africano que se propõe a descolonizar representações e discursos produzidos sobre o continente.
Cindir a cena, partilhar o cinema: sobre Bamako, de Abderrahmane Sissako
Authors: Veiga Roberta Oliveira
Published: March 2017

No filme Bamako (2006), o diretor mauritano Abderrahmane Sissako coloca lado a lado, num tribunal imaginário, o povo africano (expropriado de suas formas de vida) e as grandes corporações financeiras mundiais. Assim, permite ao cinema escrever a história a contrapelo. No terreno das ficções cinematográficas, atravessada pelo real, impregnada pelo pó da terra e por rostos negros, num mundo dividido e injusto, onde só os donos do capital têm voz, reescrever a história é conceder ao outro o tempo da imagem e do verbo. É, portanto, reinventar a política.
Radiofrequency ablation for hepatocellular carcinoma - analysis of the clinical outcome
Authors: Masulovic Dragan , Galun Danijel , Stevic Ruza , Filipovic Aleksandar , Bogdanovic Aleksandar , Milicevic Miroslav
Published: March 2017

Introduction/Objective. Radiofrequency ablation (RFA) is a minimally invasive treatment modality for primary and metastatic liver tumors. It can be performed percutaneously or as a laparoscopic or open surgical procedure under ultrasound or computerized tomography guidance. The objective of the study was to evaluate the clinical outcome of the initial 16 patients with hepatocellular carcinoma (HCC) managed by percutaneous RFA at a tertiary institution and to assess the efficacy of this procedure in the management of selected patients with HCC. Method. From June 2011 until December 2013, 16 patients with early-stage HCC were managed by percutaneous radiofrequency ablation at the Clinic for Digestive Surgery, Clinical Center of Serbia, Belgrade. All the patients were treated by the same team composed of an interventional radiologist and a liver surgeon. We analyzed the clinical outcome and the biologic effect of this treatment by comparing the pre- and post-treatment levels of alpha-fetoprotein (AFP). Results. Post-treatment values of liver transaminase levels returned to the pre-treatment values from Day 3. Post-treatment hospital stay was two days. Post-procedural complications included mild pain in all patients, skin necrosis at the site of the electrode puncture in five patients, and transient hepatic decompensation in one patient. In all the patients the AFP level correlated with the findings of liver imaging (ultrasound and/or magnetic resonance imaging with liver-specific contrast agent) indicating viability of the treated tumor. Conclusion. RFA is a feasible and effective procedure providing favorable clinical outcome in patients with early-stage HCC.