bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficient Near-Infrared Spectrum Detection in Nondestructive Wood Testing via Transfer Network Redesign
Authors: Jiang Dapeng , Wang Keqi , Li Hongbo , Zhang Yizhuo
Published: February 2024

This study systematically developed a deep transfer network for near-infrared spectrum detection using convolutional neural network modules as key components. Through meticulous evaluation, specific modules and structures suitable for constructing the near-infrared spectrum detection model were identified, ensuring its effectiveness. This study extensively analyzed the basic network components and explored three unsupervised domain adaptation structures, highlighting their applications in the nondestructive testing of wood. Additionally, five transfer networks were strategically redesigned to substantially enhance their performance. The experimental results showed that the Conditional Domain Adversarial Network and Globalized Loss Optimization Transfer network outperformed the Direct Standardization, Piecewise Direct Standardization, and Spectral Space Transformation models. The coefficients of determination for the Conditional Domain Adversarial Network and Globalized Loss Optimization Transfer network are 82.11% and 83.59%, respectively, with root mean square error prediction values of 12.237 and 11.582, respectively. These achievements represent considerable advancements toward the practical implementation of an efficient and reliable near-infrared spectrum detection system using a deep transfer network.
Human Cytomegalovirus (HCMV) Genetic Diversity, Drug Resistance Testing and Prevalence of the Resistance Mutations: A Literature Review
Authors: Grgic Ivana , Gorenec Lana
Published: February 2024

Human cytomegalovirus (HCMV) is a pathogen with high prevalence in the general population that is responsible for high morbidity and mortality in immunocompromised individuals and newborns, while remaining mainly asymptomatic in healthy individuals. The HCMV genome is 236,000 nucleotides long and encodes approximately 200 genes in more than 170 open reading frames, with the highest rate of genetic polymorphisms occurring in the envelope glycoproteins. HCMV infection is treated with antiviral drugs such as ganciclovir, valganciclovir, cidofovir, foscarnet, letermovir and maribavir targeting viral enzymes, DNA polymerase, kinase and the terminase complex. One of the obstacles to successful therapy is the emergence of drug resistance, which can be tested phenotypically or by genotyping using Sanger sequencing, which is a widely available but less sensitive method, or next-generation sequencing performed in samples with a lower viral load to detect minority variants, those representing approximately 1% of the population. The prevalence of drug resistance depends on the population tested, as well as the drug, and ranges from no mutations detected to up to almost 50%. A high prevalence of resistance emphasizes the importance of testing the patient whenever resistance is suspected, which requires the development of more sensitive and rapid tests while also highlighting the need for alternative therapeutic targets, strategies and the development of an effective vaccine.
ANALISIS DAN STRATEGI BUDI DAYA MAGGOT DALAM PENGELOLAAN SAMPAH ORGANIK
Authors: Ruhmawati Tati , Wahyudin Uyu , Saripah Iip , Sudiapermana Elih , Suryadi Ace , Robandi Babang , Hasanah Viena Rusmiati , Komar Zaenal , Rosita Neng Ayu
Published: February 2024

Pengelolaan sampah yang berkelanjutan merupakan tanggung jawab atas konsumsi dan produksi, sesuai dengan Sustainable Development Goals (SDGs). Menurut data dari Badan Pusat Statistik Kabupaten Karawang, pada tahun 2021, diperkirakan jumlah sampah organik yang dihasilkan setiap hari di wilayah Desa X berkisar antara 16,13 hingga 18,43 ton. Jumlah sampah organik yang tinggi ini menjadi masalah utama dalam hal kebersihan dan kesehatan lingkungan di wilayah tersebut. Masyarakat di Bank Sampah Desa X mencoba memanfaatkan sampah organik dengan cara menggunakannya sebagai pakan untuk larva lalat (maggot), namun tingkat keberhasilannya baru mencapai 30%. Penelitian di Desa X pada bulan Oktober 2023 bertujuan untuk mengetahui permasalahan yang dihadapi dan strategi dalam mengoptimalkan budidaya maggot. Sampel terdiri dari tiga informan, yaitu pihak Desa X, direktur Bank Sampah X, dan staf Desa X. Penelitian dilakukan menggunakan metode deskriptif dengan pendekatan kualitatif, dan teknik analisis untuk perumusan strategi adalah analisis Fishbone Diagram. Berdasarkan analisis tersebut, faktor penyebab permasalahan di Bank Sampah X antara lain: kurangnya pengetahuan dan pelatihan, mesin sudah usang dan dana tidak mendukung, kurangnya sarana dan prasarana, karakteristik sampah yang tidak sesuai, kurangnya komunikasi dan pemantauan, kurangnya peran karang taruna setempat, adanya predator maggot, dan kurangnya peran karang taruna setempat. Kegiatan pemantauan dan evaluasi merupakan strategi untuk mengatasi permasalahan tersebut.
Dampak konsumsi biskuit kelor dan plasebo pada siswi dengan kebiasaan konsumsi teh sesudah makan terhadap peningkatan kadar hemoglobin
Authors: Hasugian Debora Katarina , Handini Myrnawati Crie , Sembiring Rinawati , Ketaren Otniel , Sinaga Janno , Sitorus Mido Ester J
Published: February 2024

Remaja putri yang mengalami penurunan hemoglobin (Hb) masih menjadi masalah kesehatan di Indonesia. Kebiasan konsumsi biskuit kelor merupakan salah satu alternatif untuk meningkatkan kadar Hb pada remaja putri. Penelitian ini bertujuan untuk mengetahui dampak konsumsi biskuit kelor dan placebo pada siswi dengan kebiasaan konsusmi teh sesudah makan terhadap peningkatan kadar Hb. Studi ini menggunakan metode quasy experiment dengan rancangan non randomized pretest-postest control group design. Lokasi penelitian dilakukan di kelas 2 SMP Negeri 1 Siatas Barita, Kecamatan Siatas Barita Kabupaten Tapanulis Utara, Maret 2023. Subjek penelitian adalah seluruh siswi kelas 2 SMP Negeri 1 Siatas Barita sebanyak 100 orang yang dibagi dalam dua kelompok yaitu kelompok intervensi sebanyak 50 orang dan kelompok kontrol sebanyak 50 orang yang diperoleh dengan menggunakan teknik purposive sampling. Intervensi penelitian berupa pemberian biskuit kelor dan placebo. Pengumpulan data dilakukan dengan tahap pre-test dan post-test dengan menggunakan Quik Check Hb untuk mengukur kadar Hb sebelum dan sesudah intervensi konsumsi biskuit kelor dan plasebo selama 1 bulan. Analisis data menggunakan uji T-Dependent dan T-Independent. Hasil penelitian melaporkan bahwa rerata kadar Hb yang mengkonsumsi biskuit kelor dengan kebiasaan tidak suka minum teh, mengalami perubahan kadar Hb yang signifikan. Terdapat perbedaan kadar Hb pada kelompok intervensi sebelum dan sesudah konsumsi biskuit kelor antara siswi yang suka dan tidak suka minum teh (p < 0,001). Tidak terdapat perbedaan kadar Hb pada kelompok kontrol sebelum dan sesudah konsumsi biskuit plasebo antara siswi yang suka dan tidak suka minum teh (p > 0,05). Konsumsi biskuit kelor dapat meningkatkan kadar Hb remaja putri yang tidak suka minum teh setelah makan.
Pemanfaatan pelayanan kesehatan pada pasien diabetes mellitus tipe 2
Authors: Sinurat Buenita , Hidayah Qisty Alifyah , Tarigan Gita Febiolita Br , Dameria Dameria , Samosir Frans Judea , Sibagariang Eva Ellya , Silalahi Marlinang Isabella
Published: February 2024

Kunjungan rutin pada failitas kesehatan dapat meningkatkan pengelolaan penyakit dan pencegahan komplikasi pada penderita diabetes mellitus tipe 2. Laporan rutin Dinas Kesehatan Propinsi Sumatera Utara menunjukkan rendahnya pemanfaatan layanan kesehatan di antara pasien DM tipe 2. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang berhubungan dengan pemanfaatan pelayanan kesehatan pada penderita diabetes mellitus tipe 2. Studi cross-sectional diselenggarakan di 3 puskesmas yang ada di Kabupaten Langkat pada bulan Juni - Juli 2022. Sebanyak 125 orang penderita DM tipe 2 disertakan dalam studi ini dengan mengisi kuesioner yang berisi pernyataan-pernyataan yang relevan dalam menyelidiki prediktor pemanfaatan layanan kesehatan. uji Chi Square digunakan untuk menganalisis korelasi antara variabel bebas dengan variabel terikat (α=0,05). Hasil studi menunjukkan hubungan yang signifikan antara pengetahuan (p=0,018), aksesibilitas (p=0,011), kepemilikan jaminan kesehatan (p=0,002), dan peran keluarga (p=0,022) dengan pemanfaatan pelayanan kesehatan oleh penderita diabetes melitus tipe 2. Diharapkan agar puskesmas rutin memberikan edukasi kepada pasien DM tipe 2 dan masyarakat dengan melakukan pendidikan kesehatan mengenai pencegahan dan pengelolaan DM tipe 2.
Individual and environmental risk factors for tuberculosis disease
Authors: Simangunsong Pahala Maringan Jubel , Wau Herbert , Rusanti Rina
Published: February 2024

This study aimed to analyse the association of individual and environmental factors with tuberculosis infection. The cross-sectional study was conducted in Puskesmas Sering, located in Medan Tembung subdistrict, North Sumatra, in November 2022. A total of 56 people were sampled in this study. Data were collected directly from the subjects by interview using a questionnaire sheet distributed to the respondents. Chi-square test was used to determine the significance of risk factors with tuberculosis disease. The results of the study showed that the prevalence of tuberculosis was 73.21%.  The Chi Square test showed that all the risk factors such as age (0.002), gender (0.006), smoking habit (0.009), population density (0.014) and environmental sanitation (0.002) were significantly associated with tuberculosis disease.
Patient experiences in primary health care services in the JKN era: A qualitative study
Authors: Hartono Hartono , Siagian Masryna , Siahaan Marlina Elpiani , Tambunan Ester Theresia , Sibagariang Eva Ellya
Published: February 2024

Implementing JKN (Jaminan Kesehatan Nasional) in primary healthcare is expected to support the accessibility and success of early treatment and reduce the burden on secondary healthcare facilities. Patient experience can provide information on the quality of health services from different perspectives to provide valuable input for improving the quality of care. This study explores patients' experiences in utilizing health services in primary healthcare services in the JKN era. This research used a qualitative approach with a case study design conducted at the Puskesmas Tangkahan Durian, Langkat Regency. The researchers collected data through oral questioning with 11 informants, following previously developed in-depth interview guidelines. Researchers have also made direct observations of the health services carried out. The study results showed that patients had a fairly positive experience accessing health services at public health center/puskesmas. There was no discrimination or difference in treatment among health workers in JKN patients or general patients. Patient complaints are only in the location of the seats in the waiting room that are not arranged to interfere with patient mobility. Another criticism is that officers do not come to the public health center on time according to predetermined operating hours. Public health center management should increase the discipline of officers regarding service operating hours and consider the seating layout in the patient waiting room.
Quality of life and GERD incidence in medical students: A cross-sectional study
Authors: Saragih Agnes Fransisca , Purba Desi Natalia , Silaen Mangatas , Fibrini Dewi
Published: February 2024

Medical students are highly susceptible to GERD due to the intense pressure and hectic pace of medical education. Risk factors for GERD in medical students include inadequate knowledge, poor dietary habits, frequent coffee consumption, and high stress levels. This cross-sectional study enrolled 250 students. Data were analysed using chi-squared test and logistic regression. The results showed a significant association between knowledge (0.000), diet (0.000) and coffee consumption (0.002) with GERD in medical students. Stress was not a significant risk factor in this study (0.127). Regression modelling showed that improving diet can minimise the risk of GERD by a factor of one. There is a need to improve diet and lifestyle in medical students to minimise GERD.
The habit of indiscriminate spitting in betel chewing
Authors: Barus Aguslina Wati Kristina , Hidayat Wisnu , Bangun Henny Arwina
Published: February 2024

Betel nut consumption is a customary practice in Simalungun society and is frequently observed during typical and routine events. Nevertheless, there persists a group of individuals who are inclined towards crude expectoration behavior, depositing residual betel within various locations, including public domains such as markets. The focus of this investigation is to conduct an in-depth inquiry into the antecedents of such indiscriminate spitting tendencies exhibited among traders of betel nuts within the Saribudolok Traditional Market, located within the jurisdiction of the Simalungun Regency. This qualitative investigation utilized a phenomenological strategy. Seven informants were interviewed. These include betel nut sellers, visitors or purchasers, healthcare practitioners, and market managers. Observations were also made by the researchers throughout the data collection process. The triangulation technique was employed to verify all the data collected through the interviews and observations. Additionally, the researcher utilized a matrix to categorize the data based on the research objectives and questions.  The data analysis followed the Miles and Huberman model, revealing that the practice of carelessly spitting betel residue among traders who consume betel is due to inadequate knowledge of healthy and hygienic living habits as well as unawareness of the dangers associated with spitting betel residue. The lack of education provided by health workers on the hazards of careless spitting and the consequent risk of disease transmission also contributes to this behavior.
Effectiveness of red betel leaf extract cream for healing burn wounds
Authors: Hidayatti Mustika , Tarigan Setia Budi , Chiuman Linda
Published: February 2024

Burns are a frequent type of wound that can cause complications, infection and bleeding. The use of plants and natural materials as wound-healing remedies has been known for a considerable period, although more scientific proof is required. The objective of this investigation is to examine the efficacy of red betel leaf extract ointment in curing burns on the backs of white wistar rats. The study used a pre-test post-test design with a control group. Twenty white rat samples were employed. The samples were split into four groups, consisting of five rats each. Betel leaf extract was prepared through maceration, whilst betel leaf extract cream was made using the oil-in-water emulsion method (M/A). A histopathology test was carried out to observe growth of fibroblast cells. Rat skin biopsy was taken from a 2 x 2 cm area, and data normality was tested with the Shapiro-Wilk test (p > 0.05). The One-way Anova test (p < 0.05) was used to assess the differences between the groups. To determine the most effective treatment group, a post hoc test using LSD technique was performed. The findings showed that the average percentage of burn wound healing in the control group (P0) compared to groups P1, P2, and P3 was very different.  The analysis reveals that the application of 15% betel leaf extract cream proves to be superior in treating burns in white mice in contrast to 7.5% and 10% betel leaf extract cream. At a 15% concentration, secondary metabolite compounds found in betel leaf extract are already effective in treating wounds. However, at lower concentrations they only inhibit microorganisms, making them less effective in promoting wound healing.
Effectiveness of green betel leaf extract cream in healing cut wounds
Authors: Aulia Hilda Rafni , Wienaldi Wienaldi , Fioni Fioni
Published: February 2024

Green betel leaf (Piper betle L.) is widely used in the healing of cut wounds. The aim of this study was to investigate the efficacy of green betel leaf extract cream in the healing of cut wounds on the skin of white Wistar rats. The design employed was a pre-test post-test with a control group design and a sample size of 20 white rats divided into four groups. Betel leaf extract was prepared using the maceration method, while a cream preparation of betel leaf extract was prepared using the oil-in-water emulsion type (M/A). Macroscopic histopathological evaluation was performed by examining fibroblast growth. A one-way analysis of variance (ANOVA) test (p < 0.05) was used to determine the difference between groups, and a post hoc least significant difference (LSD) test was used to analyze which treatment group had the greatest efficacy. Technical terms were explained upon first use, and the language used was clear, objective, and value-neutral to improve academic quality. The text was free from grammatical errors, spelling mistakes, and unnecessary jargon. A one-way analysis of variance (ANOVA) test (p < 0.05) was used to determine the difference between groups, and a post hoc least significant difference (LSD) test was used to analyze which treatment group had the greatest efficacy. The study revealed a substantial difference in the average wound healing rates between the control group (P0) and treatment groups P1, P2, and P3. This is due to the lack of active substances in the control group (P0), which aids in accelerating the wound healing process. Notably, the 15% green betel leaf extract cream demonstrated superior efficacy in healing wounds in white rats compared to the 10% and 25% green betel leaf extract creams. The results indicated no significant difference between the application of 15% and 25% green betel leaf extract cream. This is due to the fact that secondary metabolite compounds present in the extract produce a healing effect on wounds at these particular levels. However, lower concentrations only act as microorganism inhibitors, rendering them less effective for promoting wound healing.
Celery leaf extract cream is a potential wound healing agent
Authors: Akalili Cory Cintia , Pratama Irza Haicha , Chiuman Linda
Published: February 2024

Natural ingredients have been widely used for wound care and healing because of their flavonoid, saponin, and tannin contents, which can facilitate the healing process. This study aimed to examine the efficacy of celery leaf extract cream in the treatment of cutaneous wounds on the surfaces of white Wistar rats. This study involved laboratory-based experimental research utilizing a pretest-posttest with a control group design. Twenty white rats were sampled for this study and divided into four groups, each consisting of five rats, including one control group and three treatment groups. The extract was obtained via maceration, whereas the celery leaf extract cream contained an oil-in-water emulsion. A one-way Anova test was used to test differences between groups (p < 0.05), and a Post Hoc test with LSD technique was conducted to determine the most effective treatment group. Celery leaf extract cream has been found to be more efficient in accelerating skin regeneration and stimulating fibroblast proliferation than base cream. This is evidenced by the superior performance of the celery leaf extract cream treatment group in closing the incision wound, as well as the group's higher production of fibroblasts that are essential for wound healing, compared to the base cream group. This is evidenced by the superior performance of the celery leaf extract cream treatment group in closing the incision wound, as well as the group's higher production of fibroblasts that are essential for wound healing, compared to the base cream group. The anti-inflammatory and antioxidant properties of the flavonoids found in celery leaves can potentially prevent the formation of free radicals and expedite wound healing.
Potential of gambier leaf ethanol extract cream for incised wound healing
Authors: Arif Maria Nisaul , Lumbantobing Christina J. R. Esmaralda , Chiuman Linda
Published: February 2024

Incised wounds are highly susceptible to bacterial infection, which requires stimulation of healing and restoration of normal function of the injured body part. This study aimed to test the effect of gambier leaf ethanol extract cream administration on the acceleration of wound healing on the skin surface of male Wistar rats. The research used a pre-test post-test with a control group design. Twenty male white rats were divided into four groups: control group (P0), treatment group 1 (P1), treatment 2 (P2), and treatment 3 (P3). The incision wounds in white rats were treated twice a day (in the morning and evening) for 14 days. Wound healing was observed by measuring the average length of the wound every day, from the first day of wounding until day 14. Statistical tests used were one-way ANOVA and post-hoc LSD test (p < 0.05). In this study, it was found that the 15% gambier leaf extract cream was more effective in wound healing in white rats than the 5% and 7.5% gambier leaf extract creams. However, in the group treated with 7.5% gambier leaf extract cream, the situation was already close to that in the treatment group treated with 15% gambier leaf extract cream. This is because, at a concentration of 7.5%, the secondary metabolite compounds in the gambier leaf extract had an effect on wounds, but at a concentration of 15% gambier leaf extract cream, the effect was similar to that of 15% gambier leaf extract cream.
Effect of sunkist orange peel nanoparticle granules on cardiac and aorta histopathology in diabetic rats
Authors: Sihotang Widya Yanti , Putri Indah Juwita Dwi , Henny Henny , Suandy Suandy , Mutia Maya Sari
Published: February 2024

Sunkist oranges (Citrus sinensis (L.) Osbeck) is rich in anthocyanins (95% of which are represented by cyanidin-3-glucoside and cyanidin-3-6"-malonyl-glucoside), flavanones (hesperidin and narirutin), hydroxycinnamic acid, carotenoids, sugars, minerals, and fiber, which offer health benefits. This study aimed to evaluate the efficacy of sunkist orange peel nanoparticle granules on the histopathological appearance of the cardiac and aorta in alloxan-induced diabetic rats. This study used a post-test experimental design, with a control group. Twenty-five male Wistar rats were randomly divided into five groups: negative control (alloxan+distilled water), positive control (alloxan+metformin), treatment 1 (alloxan+granular nanoparticles 50 mg/kg BW), treatment 2 (alloxan+granular nanoparticles 70 mg/kg BW), and treatment 3 (alloxan+granular nanoparticles 100 mg/kg BW). The heart and aorta were prepared for observation using 10x ocular magnification and 40x objective lens magnification. Kruskal-Wallis statistical test results revealed a significant difference in the average cardiac histopathological score between the treatment groups (p = 0.011). The amount of aortic endothelial cell damage can be seen from the presence of foam cells in the K(-) treatment group, while the K(+), P1, P2, and P3 groups did not have foam cells in the aortic endothelium. The findings of this study indicate that sunkist orange peel extract nanoparticles in granular form improve cardiac and aortic histopathology, with a dose of 100 mg/kg BB being the best dose for improving cardiac and aortic histopathology.
Effectiveness of durian peel ethanol extract for lowering blood sugar levels in alloxan diabetic wistar rats
Authors: Budi Andre , Nababan Samuel Maringan Tua , Nardi Leo
Published: February 2024

High blood sugar levels can be influenced by several factors, including high-carbohydrate food consumption and a lack of physical activity. To minimize the side effects of hyperglycemic treatment, efforts have been made to explore anti-hyperglycemic compounds from other sources, such as durian peel (Durio zibetthinus Murr.). This study aimed to determine the effectiveness of ethanol extract from durian peel in lowering alloxan-induced blood sugar levels in Wistar rats (Rattus novergicus). The study is an experimental research employing an alloxan-induced diabetic rat model. The rats were divided into five different groups: Group I (negative control), Group II (positive control), Group III (dose 25 × 10–30/gBW), Group IV (dose 50 × 10–30/gBW), and Group V (dose 100 × 10–30/gBW). The durian peel used in this study was extracted using the maceration method with ethanol as the solvent. The results of this study indicate that ethanol extract from durian peel significantly reduced blood sugar levels after 10 to 15 days of durian peel extract administration (p < 0.05).
Anxiety in patients treated with hemodialysis
Authors: Yunia Eva Anita , Saragih Julwansa , Damanik Derma Wani , Dewi Rani Sartika
Published: February 2024

Patients with renal failure undergoing hemodialysis often experience anxiety due to various individual, socioeconomic, and environmental factors. This study aimed to analyze the factors associated with anxiety in these patients. This was a quantitative, cross-sectional study. The risk factors for anxiety investigated in this study were education, duration of hemodialysis, knowledge, and family support. The study included 50 patients with renal failure undergoing hemodialysis (total sampling). Data were collected directly by distributing questionnaires to the patients. Data were analyzed using the chi-square test and logistic regression analysis (α=0.05). The results showed that education level was not significantly associated with anxiety in these patients (p= 0.816). However, the duration of hemodialysis (p= 0.023) and patient knowledge (p= 0.048) were significantly associated with the anxiety experienced by the patients. Family support was a protective factor against anxiety in these patients (P = 1.00). The dominant variable affecting patient anxiety is the duration of hemodialysis (p=0.041; PR = 4.1; 95%CI 1.061-16.107). This means that patients undergoing hemodialysis for more than 6 months are 4.1 times more likely to experience moderate anxiety compared to patients who have been undergoing hemodialysis for 6 months or less.
Non-pharmacological treatments in cancer pain management
Authors: Edlin Edlin , Lina Juliana , Nazara Novita Mirna Sari
Published: February 2024

Non-pharmacological therapies have recently become the focus of attention in many countries, including pain management in patients with cancer. This study aimed to explore the latest scientific evidence regarding pain management using non-pharmacological therapies in patients with cancer. The method used was a scoping review using the PRISMA-ScR framework. A literature search was conducted using four databases: PubMed, DOAJ, and Google Scholar, and published in the range of 2018-2023. There of 992 potentially relevant articles and 10 eligible articles were selected. The results of the study showed that nonpharmacological therapy was effective in reducing the pain scale in cancer patients based on the significant value and effect size of providing interventions to patients.
Antibiotics self-medication practices among students in Universitas Prima Indonesia
Authors: Novriani Erida , Neswita Elfia , Razoki Razoki
Published: February 2024

The irrational use of antibiotics can endanger health by causing unwanted drug reactions, side effects, and drug resistance. This study aimed to analyze the patterns of antibiotic self-medication among university students. This descriptive cross-sectional study was conducted at Prima Indonesia University in October 2023. A total of 307 randomly selected students from various faculties (health science clumps and non-health science clumps) filled out questionnaires distributed via Google Forms. The collected data are then analyzed descriptively to obtain frequency and percentage data, which are then presented in the form of tables and narratives. The results showed that about 83.39% of respondents had used antibiotics before. Most respondents used antibiotics because they were easily available (43.36%) or because of their previous experience (36.72%). The most common conditions for antibiotic use were cough and cold (47.66%), and infections (23.05%). Most respondents used antibiotics based on doctor ’sor pharmacist’s recommendations (45.31%). The duration of antibiotic use was 1-3 days (61.72%), followed by 4-7 days (31.64%) and more than 7 days (6.64%). Antibiotics were purchased from pharmacies (83.20%). The most common reactions to the overuse of antibiotics were nausea and vomiting (40.23%) and headache (32.81%). Most respondents (53.13%) consulted a doctor or pharmacist if they experienced reactions to antibiotic overuse.
Esquizofrenia: revisão histórica e características neuropsicológicas do transtorno
Authors: Guths Bruna Oliveira , Sausen Tiago Rafael
Published: February 2024

Introdução. A esquizofrenia é um transtorno mental grave que provoca um sofrimento psíquico no sujeito em decorrência de seus sintomas, como delírios e embotamento afetivo, sendo necessário a utilização de medicamentos antipsicóticos, acompanhamento psiquiátrico e psicológico ao longo da vida deste sujeito. Objetivo. Trazer informações sobre o transtorno esquizofrênico em forma de revisão histórica, abrangendo os avanços em estudos neuropsicológicos e classificações nas edições do DSM (Manual Diagnóstico e Estatístico de Transtornos Mentais).  Método. Revisão bibliográfica, realizando uma reflexão sobre obras já existentes no campo de estudos sobre a esquizofrenia. Conclusão. A psicoterapia desempenha um papel essencial nos estudos sobre o transtorno pois tem uma visão biopsicossocial, ou seja, além do sujeito, aplicando técnicas e intervenções condizentes com a subjetividade do paciente e sua rede de apoio, estabelecendo relação terapêutica e melhorando a saúde mental do mesmo de modo multidisciplinar junto dos profissionais da saúde envolvidos neste caso.
FRACTAL DIMENSION OF THE POROUS STRUCTURE OF CELLULAR CON-CRETE
Authors: Suleymanova Lyudmila , Ryabchevskiy I. , Pogorelova I. , Bogacheva M.
Published: February 2024

The study of the fractal dimension of pores in cellular concrete and aerated concrete blocks significantly influences the understanding of the porous structure of materials. One of the key methods for estimating this dimension is cell counting. The fractal dimension of pores indicates the degree of their dense distribution and is closely related to the physical properties of the material, such as heat and sound insulation. The results of the study showed that an increase in the fractal dimension of pores is associated with an increase in the number of smallest pores and the complication of their spatial arrangement. At the same time, the use of the cell counting method allows to estimate accurately this fractal dimension, based on the number of cells containing pores at different scales. One of the significant aspects is the correlation of the fractal dimension of pores with their area and size. This makes it possible to evaluate the roughness of pores and their distribution in the material, as well as to understand how an increase in pore size leads to a decrease in their number and thickening of the walls between them. The fractal dimension of pores makes it possible to characterize the structure of the pore space, which is important for understanding the microstructure of the material. Manipulating the microstructure of cellular concrete using fractal dimension analysis can improve its thermal insulation, strength and sound insulation, opening new possibilities for creating more efficient building materials
Uso de complejos híbridos estabilizados de ácido hialurónico en rosácea. Serie de casos
Authors: Lara del Valle Daniela Ruth , Romano Lozano Viviana
Published: February 2024

Rosacea is a chronic inflammatory disease that mainly affects women in adulthood. Pathophysiologically, there are changes in inflammatory factors, vasculature, and neurogenic alterations. The treatment is usually combined: application of topical, systemic treatment, and laser apparatus. The article aims to show the results of two Mexican patients who were administered intradermal stabilized hyaluronic acid hybrid complexes following the standardized bioaesthetics points technique and with a protocol of two applications separated by three weeks between the first and second application. Publishing this series of cases helps demonstrate the safety and effectiveness of using stabilized hyaluronic acid hybrid complexes for inflammatory dermatoses such as rosacea.
ГЕНДЕРНА РІВНІСТЬ ЯК ОСНОВНЕ ЗАВДАННЯ ДЕРЖАВ-УЧАСНИЦЬ РАДИ ЄВРОПИ: ПРОБЛЕМИ ПРИВЕДЕННЯ ЗАКОНОДАВСТВА УКРАЇНИ ДО ACQUIS ЄС
Authors: Олендарьов О. В.
Published: February 2024

Метою статті є характеристика гендерної рівності як основного завдання Держав-учасниць Ради Європи, визначення проблем приведення законодавства України до acquis ЄС у цій сфері та надання пропозицій щодо їх вирішення. Проаналізувавши національне законодавство України, автор констатує, що на першому місці в нормах права зазначено жінок, а на другому чоловіків. А от на європейському рівні, у Директивах ЄС навпаки, на першому місці згадуються чоловіки. Зазначається, що таке положення речей свідчить про очевидне досягнення балансу в правовому регулюванні прав і чоловіків, і жінок у Європі – той стан, коли суспільство сприймає гендерну рівність як цивілізований підхід у правовому регулюванні. А от в Україні така вказівка спочатку саме на жінок дозволяє констатувати все ж певні настрої суспільства, коли є стереотипи, що в пріоритеті знаходяться чоловіки й тому законодавці для підкреслення гостроти проблеми, доцільності приділення до неї уваги акцентують увагу на необхідності встановлення гендерної рівності, зайвий раз наголошуючи саме на правах жінок. Робиться висновок, що наукова доктрина має паритетно підходити до досліджень проблем гендерної рівності, приділяти увагу проблемам рівного доступу чоловіків, зокрема як осіб з сімейними обов’язками і без такого статусу до користування різними правами, що має утверджувати сучасне цивілізоване право. Очевидно, що європейська правова доктрина гендерної рівності підлягає ще більшому дослідженню в Україні для правильного усвідомлення принципових положень її змісту, транспонування положень acquis ЄС до національного законодавства України та утвердження дійсної гендерної рівності, а не відстоювання прав жінок за рахунок зрушень прав чоловіків на друге місце
СОЦІАЛЬНИЙ ЗАХИСТ ПРАЦІВНИКІВ БЮРО ЕКОНОМІЧНОЇ БЕЗПЕКИ УКРАЇНИ
Authors: Перепічай І. В.
Published: February 2024

На шляху зближення України з Євросоюзом актуалізуються питання ефективного та вчасного досягнення відповідних стандартів у різних сферах життєдіяльності. Розвиток України та рух у зазначеному напрямі нерозривно пов’язані з державною політикою. Невід’ємною складовою державної політики є соціальний захист, який забезпечує добробут громадян. Питання соціального захисту набувають особливого значення в умовах воєнного часу, а тим більше соціального захисту окремих категорій громадян, які здійснюють професійні обов’язки щодо протидії правопорушенням, що посягають на функціонування економіки держави й постійно знаходяться в зоні підвищеної небезпеки. Рівень соціального захисту є чинником, що мотивує та стимулює працівників до виконання своїх завдань на високому професійному рівні, самовіддано й максимально ефективно. Метою цієї статті є характеристика засад соціального захисту працівників Бюро економічної безпеки України. Зроблено висновок, що соціальний захист працівників Бюро економічної безпеки України є різновидом соціального захисту й має певну специфіку, що пов’язана з особивостями їх правового статусу. Системний аналіз нормативно-правових актів, що регулюють сферу соціального захисту працівників Бюро економічної безпеки України дозволяє конятатувати наявність значної кількості проблемних питань, які потребують відповідного вирішення. Системи законодавства у сфері соціального захисту є розгалуженою, що ускладнює правозастосування
ДЕЯКІ АСПЕКТИ ГРОШОВОГО ЗАБЕЗПЕЧЕННЯ ПРАЦІВНИКІВ НАЦІОНАЛЬНОЇ ПОЛІЦІЇ УКРАЇНИ
Authors: Гоц-Яковлєва О. В.
Published: February 2024

статті досліджені питання, пов’язані з грошовим забезпеченням працівників Національної поліції України як складовою соціального захисту поліцейських. Висвітлення цих аспектів важливе, оскільки підтримання публічної безпеки і порядку є однією з пріоритетних задач у державі, особливо в період воєнного стану. Зважаючи на специфічні умові несення служби поліцейськими, державі слід звернути увагу на рівень службової винагороди для них. Зазначено, що соціальний захист поліцейських становить систему заходів із надання пільг, послуг, матеріального забезпечення, зокрема грошового забезпечення. Констатовано, що проведені в Україні реформи щодо захисту поліцейських позитивно позначилися й на діяльності поліції загалом. Проаналізовано нормативно-правові акти національного законодавства, які регулюють виплату грошового забезпечення та з’ясовано, що деякі з доплат, які є його складниками, мають тимчасовий характер, оскільки пов’язані з введенням воєнного стану в нашій державі. Зауважено, що змінами, внесеними постановою Кабінету Міністрів України від 7 липня 2022 року № 793 жодна зі складових грошового забезпечення не скасована, змінено лише підходи до виплат додаткових нагород, які дозволять здійснювати виплати особовому складу залежно від складності виконуваних завдань. Зроблено висновок, що грошове забезпечення є однією з важливих гарантій в системі соціального захисту працівників Національної поліції України, а його розмір дає працівникові певний рівень мотивації виконувати свої обов’язки сумлінно й ефективно. Але слід вдосконалювати національне законодавство, ураховуючи досвід європейських країн, де грошовому забезпеченню поліцейських приділено особливу увагу, адже для ефективного та оперативного функціонування поліцейських підрозділів важливим є надання їхнім співробітникам гідного матеріального забезпечення. Підсумовано, що необхідним є внесення змін до відповідного законодавства України, а саме розширення переліку надбавок, які входять до грошового забезпечення поліцейських, оскільки це буде мати позитивні наслідки, зокрема подолання корупції серед працівників поліції, забезпечення належного рівня життя цих працівників та формування престижу професії поліцейського
CFD Analysis of Pressure Drop Reduction in PEMFC Flow Channels with Distinct Cross-Section Shapes
Authors: KAPLAN Mahmut
Published: February 2024

Proton exchange membrane fuel cells (PEMFCs) have great potential to produce renewable, sustainable and clean energy and reduce air pollutants to mitigate climate change. PEMFCs consist of distinct parts including anode and cathode bipolar plates having flow channels, gas diffusion layers, catalyst layers, and membrane. The flow channel geometry influences the flow and pressure drop characteristics of the channel and cell performance. In this work, a three-dimensional (3D) CFD model is built employing SOLIDWORKS and ANSYS Workbench. The innovative configurations are generated by changing the half of 0.2 x 0.2 mm square channel to 0.3 x 0.1 mm, 0.3 x 0.15 mm, 0.3 x 0.2 mm and 0.3 x 0.25 mm rectangular section at the top. The results showed that increasing rectangular section height significantly reduced pressure drop at the anode and cathode with a slight decrease in the current density at 0.4 and 0.6 V. The new configuration with 0.2 x 0.1 mm half square section at the bottom and 0.3 x 0.25 mm rectangular section at the top decreases the current density, anode and cathode pressure drop of 11%, 69% and 58%, respectively in comparison to 0.2 x 0.2 flow channel at 0.4 V. Taking into account pressure loss along the flow channels, this configuration is a good option to improve the cell performance.
Navigating Work-Related Stress: Strategies for IT Professionals in the Tech Industry
Authors: Suganya R.V. , Vetrivel M. , Sri Devi A.
Published: February 2024

In the ever-evolving landscape of the technology industry, work-related stress has become an omnipresent challenge for IT professionals. This study aims to empower individuals in the tech sector by providing a comprehensive guide on navigating work-related stress through effective strategies. Recognizing the multifaceted nature of stressors in the tech industry, this research defines clear objectives, including the identification of prevalent stressors, evaluation of coping mechanisms, and the examination of their impact on job satisfaction and mental well-being. Drawing from a thorough review of existing literature, this study leverages the collective wisdom of past research to inform the strategies outlined. The research employs rigorous participant selection techniques to ensure diverse representation across job roles, experience levels, and organizational contexts within the tech sector. Data collection adopts a mixed-method approach, encompassing surveys, interviews, and observational techniques. Ethical considerations are paramount, with strict adherence to informed consent and participant confidentiality. Quantitative and qualitative data analysis methods are integrated to provide both statistical insights and a profound understanding of the nuanced experiences and perceptions of IT professionals. Comparative analyses are employed to uncover patterns and distinctions across various subgroups within the tech industry. Furthermore, the study suggests a proactive approach to stress management, emphasizing the importance of continuous self-assessment and the utilization of effective stress-coping strategies. It provides recommendations for individuals and organizations to foster a healthier work environment and promote employee well-being. With a longitudinal perspective, the research examines how stress and coping strategies evolve over time in response to industry changes and shifts in work practices. By shedding light on these dynamics, the study equips IT professionals with tools to thrive in the tech industry while managing the challenges of work-related stress effectively. In conclusion, this study serves as a valuable resource for IT professionals, tech organizations, and policymakers alike, offering actionable strategies and insights to alleviate work-related stress and enhance the overall quality of work life in the fast-paced world of technology.
Comparing the Performance of GARCH Family Models in Capturing Stock Market Volatility in India
Authors: Ananth Alias Rohith Bhat P. , Shakila B. , Pinto Prakash , Hawaldar Iqbal Thonse
Published: February 2024

In recent times, the prediction of stock market volatility has emerged as a central focus in the domain of financial econometrics. This paper presents an empirical analysis aimed at modelling the volatility of the Indian stock market, particularly focusing on the NSE NIFTY 50, by utilizing various GARCH models. The investigation explores the volatility of stock returns, considering the daily closing prices, and examines the influence of two external factors: Crude oil prices and the INR/USD exchange rate. The inquiry employs data encompassing the period from January 1, 2012, to December 31, 2022, for all three variables. The manuscript delves into an array of univariate GARCH models, encompassing both symmetric and asymmetric models, and assesses their performance by utilizing metrics such as the Akaike Information Criterion, Schwartz Bayesian Information Criterion, and Log Likelihood. To assess the predictive accuracy of these models, statistical error measures such as Mean Squared Error, Root Mean Squared Error, and Mean Absolute Error are employed. The findings strongly suggest that the EGARCH model is the most effective in predicting the variations of the NIFTY index. Furthermore, the research highlights the significant impact of exchange rates and crude oil prices in relation to the volatility of the stock market in India.
Historical Study of Recorded Speech: Voiceover’s Evolution
Authors: P.V. Rajlakshmi
Published: February 2024

Voiceover covers a wide spectrum from radio ads to video game character. But our journey through history, it is defined as the voice of an unseen narrator speaking. This is the initiation of voiceover’s evolution. It begins in the 19th century when the concept of recording sounds was in infancy and imagine, where the sound was a mystery waiting to be unveiled. All of the requiring professional voiceover services to convey messages effectively. It is a time when voices reach global audiences from the comfort of home studios. The ease of access to voiceover opportunities, coupled with the growth of online freelance networks, has made it simpler than ever to start a career in voiceover. It was a moment that expanded the possibilities of voice manipulation. The rise of online video platforms, especially YouTube, has opened new avenues for voiceover, at the COVID – 19 pandemic times. The internet’s vast landscape offers countless opportunities, from explainers’ videos to independent animations. This paper focused on the chronological evolution of voiceover from the era of mime shows and also the current technological advancements due to the influence of Artificial Intelligence. This study is not detailing about the algorithms, machine learning and deep learning models works. Instead, it is explained with real time living beings that involves into the evolution of voice cloning technology.
Exploring the Diasporic Consciousness in Chitra Banerjee Divakaruni’s Sister of My Heart
Authors: A. Saleema Kathoon  , J. Ahamed Meeran
Published: February 2024

Chitra Banerjee Divakaruni is an acclaimed Indian American writer known for her dazzling investigation of South Asian immigrant experiences. Divakaruni is a famous diasporic writer with a refined and modern sensibility whose contribution to the diasporic fiction is great and unique. Divakaruni beautifully presents the matrix of diasporic consciousness like nostalgia, loneliness, rootlessness, alienation, cultural conflict, questioning, etc., in her novels. Her writing affirms that diaspora is not merely scattering or dispersion but a matrix of consciousness that encompasses various conflicting characteristics. Being an immigrant in USA, Divakaruni seems to capture the experiences of the Indian immigrants with all its colours. This article attempts to explore the diasporic consciousness in the work of Chitra Banerjee Divakaruni’s Sister of My Heart.
Adopting Digital Humanities to Explore Toni Morrison’s Oeuvre: A Literary Dimension
Authors: Joshiha Bell J.B
Published: February 2024

This research paper delves into a new literary dimension of using technology to unravel the rich tapestry of Toni Morrison. It uses digital tools of sentiment analysis,character networks, and text mining to unveil the hidden nuances of her narratives. As her novels are celebrated for their African-American identity, experience, and societal complexities, this study examines the cultural, historical, and emotional landscape of her narratives through the realm of digital humanities. It deepens the understanding of her characters through the geospatial data which traces the cultural, historical, and symbolic dimensions of African Americans. Besides, it offers insights in the integration of technology and literature.