bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on Assessment of the Diameter of Thoracic Aorta by Computed Tomography of Chest
Authors: Pokhrel Sona , Sharma Rupesh
Published: February 2024

INTRODUCTION: Computed tomography (CT) is frequently used for the evaluation of different aortic diseases which is a good method of measuring the aortic diameter. Thus, knowledge of normal aortic diameters is very important in the assessment of aortic disease.

METHODS: This was a prospective cross sectional study done on 105 patients who presented in department of Radiodiagnosis in Lumbini Medical College, Palpa, Nepal from February 5th 2022 to February 4th 2023. Plain helical scan was performed using Siemens Somatom 16 slice CT scanner. CT images were obtained in supine position with full inspiration. Diameters of the aorta was measured at the level of aortic valve sinus, ascending aorta, proximal to innominate artery, transverse aortic arch, distal transverse aortic arch, aortic isthmus and descending aorta at the level of diaphragm perpendicular to the axis of the aorta.

RESULTS: Diameter of thoracic aorta was found to be maximum at ascending aorta with mean of  2.85 cm, followed by aortic valve sinus 2.80 cm, 2.68 cm at proximal to innominate artery, 2.57 cm at proximal transverse arch, 2.41 cm at distal transverse arch, 2.24 cm at isthmus and 2.03 cm at descending aorta at the level of diaphragm. There was smooth tapering of aortic diameter from ascending aorta onwards. There was a significant correlation of mean ascending aorta diameter with the age of the patients(r = 0.475, p< 0.05).

CONCLUSION: Diameter of thoracic aorta was found to be maximum at the level of the ascending aorta and minimum at the level of diaphragm. The diameter of thoracic aorta had significant correlation with the age of patients.
Prinsip dan Tujuan Pembelajaran IPS Membangun Warga Negara Berpengetahuan Luas dan Berpikir Kritis
Authors: Safitri Dea , Dean Antania S  , Dinda Oktovia  , Putri Audya Sari  , Radya Amalia  , Syifa Salsabila
Published: February 2024

Ilmu Pengetahuan Sosial (IPS) adalah salah satu mata pelajaran di sistem pendidikan nasional yang memiliki peran penting dalam membentuk pemahaman siswa tentang dunia sosial, ekonomi, politik, dan budaya di sekitar mereka. IPS bertujuan untuk mengembangkan pemahaman siswa tentang hubungan antara individu, masyarakat, dan lingkungan, sehingga mereka dapat menjadi warga negara yang aktif, terampil, dan berpikiran kritis. Pembelajaran IPS melibatkan pengajaran dan pembelajaran berbagai disiplin ilmu sosial, seperti sejarah, geografi, ekonomi, dan sosiologi. Hakekat IPS adalah pemahaman dan penggunaan konsep, prinsip, dan metode dari berbagai disiplin ilmu sosial untuk menganalisis dan memahami peristiwa dan fenomena sosial. IPS tidak hanya berfokus pada pemahaman faktual tentang fakta-fakta sejarah, geografi, atau ekonomi, tetapi juga pada pengembangan pemikiran kritis, keterampilan analitis, dan kemampuan berpikir reflektif siswa.
EFFICACY OF NICOTINAMIDE MONONUCLEOTIDE SUPPLEMENTATION (NMN) IN BLOOD NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) FOR ANTI-AGING IN ADULTS: A SYSTEMATIC REVIEW
Authors: Asrithari Dewi Made Yudha , Dananjaya I Made Dwi , Saraswati Dewi Permadi Anak Agung Sagung , Sigmahadewi Risma Nopara
Published: February 2024

Aging is a risk factor for various chronic diseases such as diabetes, dyslipidemia, metabolic, neurological, and cardiovascular disease, and other age-related disorders. Nicotinamide mononucleotide (NMN) is one of the endogenous intermediate molecules in nicotinamide adenine dinucleotide (NAD) biosynthesis, and its biological function is known to be related to an increase in NAD concentration. NAD levels decline and are critical for human health and longevity. The material and methods using a systematic review of RCT, with participants of healthy adults aged between 20-65 years old, agreed to take NMN supplementation compared to Placebo. The inclusion criteria are RCT studies regarding NMN administration with an outcome to prevent aging using primary objective measurement of blood nicotinamide adenine dinucleotide (NAD) concentration. Trial quality was assessed using the JBI checklist. We included six studies with an average duration of intervention between 10-12 weeks with a dosage of NMN 250-900mg/day. All six studies showed that NMN supplementation can significantly improve blood NAD concentration and cause only mild adverse effects during the trial. In conclusion, NMN supplementation has a significant clinical impact in preventing adult aging.
MULTISENZORICKÁ INTEGRACE
Authors: Mlíka R , Vingrálková E , Vyskotová J
Published: February 2024

Jednou ze základních funkcí mozku, spolu s celým nervovým systémem, je řídit a produkovat chování, jehož zásadní složkou je pohyb. Ačkoliv se již neakceptuje názor, že pohyb je vždy iniciován z vnějšího prostředí jako pouhá odpověď na senzorickou stimulaci, je za fyziologických okolností pro zahájení a provádění pohybu naprosto zásadní aferentní informace, zejména pak proprioceptivní. O pohybu je tedy potřeba hovořit vždy jako o senzori-motorické aktivitě, přičemž produkci cíleného pohybu předchází vyhodnocení aktuální senzorické situace. Dobře dnes známe funkci jednotlivých smyslových systémů, ale teprve poslední dekády výzkumu ukazují, jakým způsobem tyto systémy spolupracují, vzájemně se ovlivňují a v některých případech i zastupují. Děj, který vystihuje problematiku sdílení informací mezi smysly, označujeme multisenzorickou integrací (MSI). Jedná se o naprosto zásadní proces zpracování smyslových dat, jehož porucha se nutně odrazí v některé oblasti chování jedince. Toto sdělení přináší základní vymezení pojmů týkajících se MSI, posuzuje vývoj této schopnosti a nastiňuje její současné terapeutické využití v rehabilitaci.
Advances in new materials for bone tissue engineering simplifying postoperative rehabilitation: Recent Scientific Breakthroughs
Authors: Furka Daniel , Dueñas Santana Julio Ariel , Furka Samuel
Published: February 2024

Introduction: Bone tissue engineering has emerged as a promising field in regenerative medicine, aiming to develop innovative materials and approaches for bone repair and regeneration, which also leads to the simplification and search for new approaches in postoperative rehabilitation. The integration of novel materials into scaffolds and implants plays a crucial role in improving bone tissue engineering strategies. In recent years, scientific research has made significant progress in identifying and characterizing novel materials with superior properties and functionalities.

Aim: This article explores the most recent scientific findings and research breakthroughs concerning novel materials for bone tissues, focusing on their biocompatibility, mechanical properties, bioactivity, and potential clinical applications.

Conclusion: In recent years, the field of bone tissue engineering has witnessed remarkable advancements in the development of novel materials for bone repair and regeneration, which also simplify the medical rehabilitation of the patient. From bioactive glasses and calcium phosphate-based materials to biodegradable magnesium-based materials and graphene-based composites, researchers have explored a wide range of materials with diverse properties and functionalities. As the field continues to evolve, the integration of cutting-edge technologies, such as 3D printing and nanotechnology, is expected to further enhance the efficacy and clinical relevance of these novel materials, ultimately benefiting patients with bone defects and diseases.
Dysfunkcia sakro-iliakálneho kĺbu - úskalia diagnostiky a možnosti liečby z pohľadu neurochirurga
Authors: Chochol Juraj , Chocholová Alica , Illéš Róbert , Zemková Erika , Mikláš Jakub , Džubera Andrej
Published: February 2024

Chrbtica ako dynamická štruktúra podstupuje nepretržité zmeny počas celého života. Unikátne anatomické usporiadanie jednotlivých štruktúr a ich vzájomné prepojenie umožňuje nielen prostý široký rozsah pohybu, avšak aj jej neustále prispôsobovanie sa požiadavkám záťaže človeka – nielen v aktuálnom pohybe, ale aj v priebehu starnutia a plynutia rokov.

            Spinálna neurochirurgia napriek intenzívnym a extenzívnym vyšetrovacím metódam nie je častokrát schopná presne identifikovať príčinu vzniku vertebrogénnych bolestí. Ich etiológia zostáva často nejasná, napriek rádiologickým vyšetreniam pacienta pre mnohé možné generátory bolesti a mechanizmy vzniku.

Dysfunkcia sakro-iliakálneho (SI) kĺbu je poddiagnostikovanou príčinou bolestí dolného chrbta (low back pain - LBP). Diagnostika je zložitá, príznaky dysfunkcie SI kĺbov sa prekrývajú s príznakmi postihnutia lumbálnej chrbtice inej etiológie. Diagnostika je založená na anamnéze - charakter bolesti, vyžarovanie, nadväznosť na špecifické pohyby a klinickom  vyšetrení - palpačná citlivosť, distrakčný test, obrátený Laségueov príznak, Patrickov manéver – FABER. Jednoznačný korelujúci rádio-diagnostický nález nie je často možné získať.

Použitie peri/intraartikulárneho ošetrenia SI kĺbu je považované za úspešnú diagnosticko-terapeutickú modalitu na rozlíšenie bolesti pochádzajúcej zo SI kĺbu od iných vertebropatických bolestí prejavujúcich sa pod obrazom LBP a radikulárneho syndrómu dolných končatín. Základným pilierom liečby je úprava každodenných aktivít a zaťaženia SI kĺbov, dobré vedenie a osvojenie si rehabillitačných cvičení a bandážovanie. Predpokladáme, že priame peri/intraartikulárne ošetrenie SI kĺbu môže prispieť k zlepšeniu a dlhodobo uspokojivému efektu u pacientov s dysfunkciou SI kĺbu a v kombinácii s rehabilitáciou môžu priniesť dlhodobú a dostačujúcu úľavu od ťažkostí.

Dôsledné určenie diagnózy a následne správne vybraný liečebný postup je kľúčom k dobrému terapeutickému výsledku, k zlepšeniu kvality života pacienta a zachovaniu jeho práceschopnosti a funkcii v rodine i spoločnosti. Zároveň bráni nadliečeniu pacientov a predchádza zbytočným operáciám.
SUPLEMENTACE HYDROGENOVANOU VODOU SNIŽUJE PROJEVY POZÁTĚŽOVÉ SVALOVÉ BOLESTI PO VYTRVALOSTNÍM BĚŽECKÉM ZATÍŽENÍ U NETRÉNOVANÝCH MUŽŮ. RANDOMIZOVANÁ, DVOJITĚ ZASLEPENÁ, PLACEBEM KONTROLOVANÁ CROSS OVER STUDIE
Authors: Valenta Michal , Botek M , Krejčí J , Chmelík F , Sládečková B , Klimešová I , Šinclová M
Published: February 2024

Východiska

Jednorázová vytrvalostní pohybová aktivita u netrénovaných osob je spojována s výskytem opožděné svalové bolesti související s probíhajícím lokální zánětem a zvýšeným oxidativním stresem. Molekulární vodík (H2) je nový selektivně působící antioxidant a protizánětlivě působící látka.

Cíl

Hlavním cílem studie bylo posoudit vliv aplikace H2 obohacené vody (HRW) na rozvoj pozátěžové svalové bolesti během 24 hod od ukončení 5 km běhu.

Metodika

V rámci randomizované studie podstoupilo 12 vytrvalostně netrénovaných mužů ve věku 23,6 ± 3,4 roku běh na 5 km s cílem dosažení nejlepšího běžeckého výkonu. V průběhu dvou dnů před zatížením a do 60 min po ukončení byla probandům aplikována celková dávka 3780 ml HRW nebo placeba. V časech 0 h, 1 h, 4 h a 24 h po zátěži byla hodnocena bolestivost dolních končetin pomocí 100 mm vizuální analogové škály. Odstup mezi oběma měřeními činil 7 dnů.

Výsledky

Aplikace HRW v porovnání s placebem signifikantně redukuje pozátěžovou bolest dolních končetin během 1. h (41 ± 21 vs. 27 ± 13 mm; p=0,017) a 4. h (34 ± 21 vs. 22 ± 15 mm; p=0,029). Rozdíly po 24 h se blížily statistické významnosti (36 ± 27 vs. 26 ± 16 mm; p = 0,081).

Závěr

Konzumace HRW významně snižuje pozátěžovou percepci svalové bolesti s tendencí zmírňovat i opožděnou svalovou bolest po absolvování 5km běhu u netrénované populace.
STANDARDIZACE 1. ČESKÉ VERZE DOTAZNÍKU MANCHESTER RESPIRATORY ACTIVITIES OF DAILY LIVING QUESTIONNAIRRE – PILOTNÍ STUDIE
Authors: Kopecká T , Raisová K , Cuberek R , Rodová Z , Kršáková Z
Published: February 2024

Východisko: V článku je představen dotazník Manchester respoiratory of daily living questionnairre jako nástroj vhodný pro hodnocení soběstačnosti pacientů s chronickou obstrukční plicní nemocí (CHOPN), takový nástroj v České republice chybí. Článek popisuje metodologickou část standardizace dotazníku.

Soubor a metody: Proces standardizace podléhá metodologickým podmínkám, tento článek podrobně rozebírá fázi pilotního šetření. Pilotní šetření v tomto případě proběhlo na 20 odbornících z praxe a 20 pacientech s CHOPN. Připomínky, jež vyvstaly z pilotního šetření dále posoudila, diskutovala a zapracovala komise odborníku společně s autorkou a překladateli.

Výsledky: Pilotní studie ukazuje, že z odpovědí od všech respondentů pouze 5 % (840 odpovědí, celkem 42 připomínek) z nich mělo připomínku k formulaci otázky. Nejvíce připomínek bylo z řad ergoterapeutů a fyzioterapeutů, a to v přepočtu 2,4 %.

Závěr: Na základě pilotního testování mohla být 1. česká verze dotazníku postoupena k dalším metodologickým krokům po jejímž dokončení bude moct být dotazník uveden do praxe a vznikne tak nástroj na objektivizaci úrovně běžných denních činností.
AUTOTEFLEXNÉ PRENATÁLNE, POSTNATÁLNE TERAPEUTICKÉ POLOHY A ŠTANDARDNÁ LIEČBA, ICH VPLYV NA SYMPTÓMY HYPERAKTÍVNEHO MECHÚRA U PACIENTOV PO CIEVNEJ MOZGOVEJ PRÍHODE
Authors: Oravcová K , Hagovská M , Mihaľová M , Miľanová J , Petríková A
Published: February 2024

Cieľ: Primárnym cieľom práce bolo hodnotenie vplyvu konceptu Autoreflexné prenatálne, postnatálne terapeutické polohy (APPP®) a štandardnej fyzioterapie na symptómy hyperaktívneho močového mechúra. Sekundárnym cieľom práce bolo hodnotenie vplyvu uvedenej liečby na zvládanie aktivít každodenného života. Súbor a metódy: Výskumnú vzorku tvorilo 95 probandov muži aj ženy s diagnózou CMP v chronickom štádiu minimálne rok a viac po ataku (s priemerným vekom 57,20 ± 4,3 roka) rehabilitovaných v Špecializovanom liečebnom ústave Marína a. s. v Kováčovej. Náhodným výberom boli rozdelení do dvoch skupín - experimentálnej  a kontrolnej. Intervencia: Experimentálna skupina - cvičenie v terapeutických polohách konceptom APPP® zamerané na ovplyvnenie močenia, rovnováhy a pohyblivosti končatín. Kontrolná skupina - štandardná fyzioterapia obsahujúca prvky Bobathovho konceptu a Proprioceptívnej neuromuskulárnej terapie. Dávkovanie liečby: 2 krát denne v dĺžke trvania 30 minút, 6. dní v týždni, 4 týždne. Symptómy úniku moču boli hodnotené modifikovaným Mikčným denníkom, Dotazníkom medzinárodnej konzultácie o inkontinencii (ICIQ UI– SF), krátkym dotazníkom príznakov urgentnej inkontinencie moču (OAB-q) a aktivitami každodenného života, ktoré boli hodnotené Barthelovým indexom. Výsledky: V hodnotení symptómov úniku moču vo všetkých sledovaných parametrov neboli medzi skupinami po liečbe zaznamenané signifikantné rozdiely. V hodnotení symptómov hyperaktívneho mechúra v rámci oboch skupín boli zaznamenané signifikantné zlepšenia u oboch skupín vo väčšine sledovaných parametrov p≤0,001. V hodnotení ADL v Barthelovom indexe v jednotlivých sekciách a celkovom skóre neboli medzi skupinami po liečbe zaznamenané signifikantné rozdiely. V rámci oboch skupín boli zaznamenané signifikantné zlepšenia u oboch skupín vo väčšine sledovaných parametrov p≤0,001.

Záver: Štandardná liečebná rehabilitácia a cvičenie podľa konceptu APPP® pozitívne ovplyvňuje symptómy hyperaktívneho mechúra. Keďže výsledky po liečbe boli porovnateľné, zlepšenie možno interpretovať na základe inhibície mozgu akýmkoľvek cvičením na močový systém. Obe intervencie taktiež majú porovnateľný a pozitívny vplyv na ADL u pacientov v chronickom štádiu po CMP.
VLIV POHYBOVÉ AKTIVITY NA KVALITU ŽIVOTA U OSOB VYŠŠÍHO VĚKU – PILOTNÍ STUDIE
Authors: Gaul Aláčová P , Svobodová A , Klášterecká R , Dygrýn J
Published: February 2024

Úvod: Stárnutí naší populace sebou přináší spoustu výzev, které se vztahují na mnoho odvětví ve společnosti. Čím dál tím více rezonuje důraz na zvýšení kvality života osob vyššího věku a udržení nejvyšší možné úrovně jejich nezávislosti. Jedním z velice slibných přístupů se jeví objektivně monitorovaná pravidelná pohybová aktivita, která je “šitá na míru“ právě této věkové skupině. Objektivní monitorování pohybové aktivity umožňuje nejenom získání validních dat o pohybové aktivitě, ale zároveň umožňuje odborníkům specifickou preskripci pohybové aktivity i odhalení potenciálních rizikových faktorů u věkově závislých zdravotních komplikací a tím facilitovat včasnou intervenci v prevenci chronických onemocnění.

Cíl: Cílem práce bylo zhodnotit možnosti využití objektivního monitorovacího nástroje pro vyhodnocování pohybové aktivity v souvislosti s jednotlivými doménami kvality života u osob vyššího věku z Olomoucka.

Metodika: Pilotní studie se zúčastnilo 15 probandek z Olomoucka. Pohybová aktivita byla subjektivně hodnocena pomocí dotazníku IPAQ a kvalita života dle dotazníku WHOQOL-BREF. Objektivní monitorování pohybové aktivity probíhalo pomocí akcelerometrů Axivity AX3 kontinuálně po dobu tří týdnů.

Výsledky: Pilotní výzkum naznačil významnou shodu v reliabilitě výsledků subjektivního a objektivního hodnocení pohybové aktivity u osob vyššího věku. Statisticky významných rozdílů bylo dosaženo v psychické doméně WHOQOL-BREF při srovnání osob vyššího věku s mírnou a zdraví prospěšnou pohybovou aktivitou.

Závěr: Intenzita pohybové aktivity přímo koreluje se subjektivním hodnocením kvality života u osob vyššího věku v doméně fyzické zdraví jak u osob s mírnou, tak i vysokou pohybovou aktivitou.
The Effect Size of Blended Learning in Mathematics Learning
Authors: Mohammad Edy Nurtamam  , Baso Intang Sappaile  , Sutarto  , Novianty Djafri  , Tomi Apra Santosa  , Andri kurniawan
Published: February 2024

This study aims to determine the effect of blended learning in mathematics learning. This type of research is quantitative research with a meta-analysis approach. The inclusion criteria are research published in 2020-2023, research must be experimental methods or quasi-experiments, research related to the influence of blended learning in mathematics learning, research comes from SINTA indexed journals, Research data is obtained through google scholar, DOAJ, Mendeley and Sinta and research has complete data to calculate the value of effect size. The results of 23 studies concluded that there was a significant influence of blended learning in mathematics learning with an average effect size value of 0.83 with a large effect category. These findings provide more accurate information about the application of blended learning in mathematics learning.
Analisis Pengaruh Perputaran Kas, Perputaran Piutang, dan Perputaran Persediaan terhadap Return On Assets (ROA) PT Fast Food Indonesia Periode 2019 – 2022
Authors: Lutfika Arifa Faizati  , Hwihanus
Published: February 2024

Abstract : This research explores the history of the fastfood industry in Indonesia, tracing its rise and explaining the dynamics of a varied and competitive economy. Organizations in this field must improve operational efficiency and financial strategies to achieve optimal financial performance in the face of increasing competition. The study's main objective is to examine the effect of cash, accounts receivable, and inventory turnover on PT Fast Food Indonesia's return on assets (ROA) from 2019 to 2022. An essential measure of a company's financial health, ROA shows how well a business can turn its assets into profits. The research data came from PT Fast Food Indonesia's annual financial statements from 2019 to 2022, and the technique used was regression analysis. Based on the findings, asset utilization efficiency and ROA are significantly affected by accounts receivable and inventory turnover but not cash turnover.
Abstrak : Penelitian ini menggali sejarah industri makanan cepat saji di Indonesia, menelusuri kebangkitannya dan menjelaskan dinamika perekonomian yang bervariasi dan kompetitif. Untuk mencapai kinerja keuangan yang optimal dalam menghadapi persaingan yang semakin ketat, organisasi di bidang ini harus meningkatkan efisiensi operasional dan strategi keuangan. Menguji pengaruh kas, piutang, dan perputaran persediaan terhadap return on assets (ROA) PT Fast Food Indonesia pada tahun 2019 hingga 2022 menjadi tujuan utama penelitian. Salah satu ukuran penting kesehatan keuangan perusahaan, ROA menunjukkan seberapa baik bisnis mampu mengubah asetnya menjadi keuntungan. Data penelitian berasal dari laporan keuangan tahunan PT Fast Food Indonesia tahun 2019 hingga 2022, dan teknik yang digunakan adalah analisis regresi. Berdasarkan temuan ini, efisiensi pemanfaatan aset dan ROA secara signifikan dipengaruhi oleh perputaran piutang dan perputaran persediaan, namun tidak oleh perputaran kas.
Legal innovations in taxation of the agrarian sector of the economy
Authors:   Bila Tserkva National Agrarian University, Ukraine, Kovalchuk Inna , Pakhomova Anna ,   Bila Tserkva National Agrarian University, Ukraine, Melnyk Victoria ,   Bila Tserkva National Agrarian University, Ukraine
Published: February 2024

In the article, the authors reveal the peculiarities of taxation of the agrarian sector of Ukraine in the pre-war period and during the war, and compare it with the tax legislation of a number of European countries. The authors analyze the effectiveness of the current system and suggests ways to improve it. The authors examine the experience of taxation of agribusiness in developing countries, analyzes conceptual and practical problems associated with different tax regimes. This article examines the legal regulation of taxation of the Ukrainian agricultural sector of the economy, identifies the problems of regulatory regulation and suggests ways to optimize the tax burden on agricultural producers.
Innovative adaptations in the land management system
Authors:   Poltava State Agrarian University, Ukraine, Pylypenko Dmytro , Buryi Yevhen ,   Poltava State Agrarian University, Ukraine, Nikonenko Oleksandr ,   Poltava State Agrarian University, Ukraine
Published: February 2024

Innovative adaptations in the land management system were studied. The classification of factors affecting this system is presented. Factors affecting the land market are determined. The main factors of agricultural land pricing are systematized. An analysis of the positions of stakeholders in land relations was carried out.
Benchmarking of sustainable waste management models
Authors:   National University of Kyiv-Mohyla Academy, Nikitiuk Maksym , Chala Nina ,   National University of Kyiv-Mohyla Academy
Published: February 2024

The paper examines the potential of black soldier fly larvae (BSFL) recycling in sustainable and economically viable organic waste treatment. Recent studies demonstrate effective biowaste conversion and nutrient recycling abilities of BSFL. However, comparisons with other waste treatment methods require further investigation in terms of quantification of environmental and economic efficiency parameters. The aim of this study is to analyze the performance and viability of the BSFL model against alternative organic waste processing approaches. The research employs a case study methodology using operating data from a commercialscale BSFL recycling facility in Central Europe specializing in food industry residuals. The results show a 22% higher bioconversion rate compared to regular composting translated into 170 kg of product output per ton of organic substrate. BSFL processing leads to lowered greenhouse gas emissions from waste treatment by an average of 35% owing to significant biogenic carbon sequestration. The reduced environmental impacts coupled with marketable BSFL-derived products create the prospects for sustainable waste management. The study concludes that incentivizing businesses in the waste management sector to integrate BSFL-centered approaches leads to achieving dual economic and environmental sustainability goals. The paper contributes to knowledge on the viability of insect-based waste recycling. Further research needs include lifecycle assessments of the BSFL value chain and evaluating scaling potential.
Public management of sustainable development of Ukraine
Authors:   Dnipro Academy of Continuing Education of the  Dnipropetrovsk Regional Counci, Ukraine, Sychenko Viktor , Shevchenko Olexandr ,   V.I. Vernadsky Taurida National University, Ukraine
Published: February 2024

The article analyzes the goals of sustainable development of Ukraine in the conditions of war and found that the war started by Russia became a significant challenge for the country, provoked a huge negative impact on the environment, economy and society, nullified the gains in the field of development achieved during the 30 years of the country’s independence. It was concluded that for the further support of our country, it is necessary to follow the rules that are decisive in the European Union and the world, and especially the perception of general principles of social development, such as democracy, the rule of law, good governance; implementation of European standards and norms in the field of public administration.
Uso de la escala de Parkland en el abordaje transoperatorio de colecistitis aguda y la elección de colecistectomía subtotal
Authors: Garcés Villacis Roberth Paolo , Loaiza Merino Iván Patricio
Published: February 2024

La presente investigación aborda el problema de la colecistitis aguda, una inflamación súbita de la vesícula biliar que puede complicarse y requerir colecistectomía laparoscópica, el tratamiento de referencia. El estudio se centra en la complejidad de esta cirugía, influenciada por factores como la inflamación, historial clínico del paciente y la condición de la pared de la vesícula biliar. Se destaca que, aunque la mayoría de las colecistectomías son exitosas, la colecistitis aguda compleja puede necesitar conversiones a cirugía abierta o cambios en la técnica quirúrgica, sugiriendo la colecistectomía subtotal como una técnica de rescate. El objetivo principal es analizar la literatura médica para identificar factores clínicos que influyen en la elección de la colecistectomía subtotal y evaluar la relación entre los puntajes de la Escala de Parkland y la decisión quirúrgica, con el fin de establecer su validez predictiva. Se utilizó un enfoque metodológico basado en la revisión de casos de colecistitis aguda y la aplicación de la Escala de Parkland para predecir la dificultad quirúrgica y la necesidad de técnicas de rescate. Los resultados muestran que la Escala de Parkland es una herramienta útil para estratificar la gravedad de la enfermedad y predecir desafíos durante la colecistectomía laparoscópica, con una correlación significativa entre puntajes altos y la elección de colecistectomía subtotal. En conclusión, este estudio subraya la importancia de la Escala de Parkland y la colecistectomía subtotal en el manejo de colecistitis aguda compleja, ofreciendo una guía valiosa para la toma de decisiones clínicas en situaciones de difícil acceso quirúrgico.
Health tourism training and education and COVID-19 pandemic
Authors: Mohammadi Anahita
Published: February 2024

Health tourism focuses primarily on physical health and also improves mental and spiritual well-being and increases the capacity of people to meet their needs and better performance in their environment and society. Education and training in health tourism is very important because it reduces medical errors and increases the satisfaction of health tourists. Recently, health tourism as well as health tourism training have been negatively affected by the COVID-19 epidemic. The outbreak of coronavirus in January 2020 has severely affected many industries. Tourism education provided by universities, which requires close links with the tourism industry, has also been strongly influenced. The prevalence of COVID-19 is a major barrier to the tourism industry and education system. Although tourism education has changed from face-to-face education to online education during the COVID-19 epidemic, online education has serious constraints and cannot replace face-to-face education. In this review, we aim to investigate health tourism and health tourism education and training during the COVID-19 pandemic.
Surface morphology of biofouling in membrane bioreactor treating actual sewage
Authors: Isma M. I. Aida , Mohammad Munira , Razreena Abdul Razak Putri , Mansor Hazmin , Idris A. , Baizura M. Siti
Published: February 2024

Biofouling is the most challenging operational problem in membrane bioreactors. The goal of this study is to evaluate the foulants mechanism by profiling the foulants morphology in a membrane bioreactor treating actual sewage. A 10 m2 hollow fiber membrane was set up at MLSS of 9 g/L and HRT of 8 hours. CLSM and FESEM were used to characterize the membrane morphologies. The trans-membrane pressure was monitored, and membrane samples were analysed on weekly basis. The performance of the membrane bioreactor treating the actual sewage showed a remarkable result. The biofilm and cake layer formation dominated the majority of fouling in the MBR operation, resulting in slower permeation flux decay over time. The evaluation of fouling layers and the mechanism of biofouling development through profiling of foulant morphology using FESEM and CLSM revealed that the membrane experienced mild internal pore-clogging, implying that fouling occurred mainly on the membrane surface. The fluorescent staining of CLSM images revealed that proteins, -D-glucopyranose polysaccharides, and lipids were aggregated into clusters with protein depth thickness recorded at 22 μm. FESEM images revealed that the membrane experienced mild internal pore-clogging and had marginally reduced the overall water permeability and severely reduced the mass transfer coefficient. It can be concluded that proteins and microbial cells were the primary constituents of the fouling layer which may have contributed to the membrane performance deterioration after fouling.
The effects of amitriptyline on human embryonic kidney cells growth and proliferation in vitro
Authors: Dehghani Atefe , Vafaee Elham , Rezvani Amirmohammad
Published: February 2024

Many studies have shown that antidepressants, including amitriptyline, can cause side effects on normal human cells, although the exact effects of amitriptyline on normal human cells are unclear. Accordingly, the present study investigated the cytotoxic effects of amitriptyline on the human embryonic kidney cell line. In this experimental-laboratory study, cells were divided into control group (no drug-treated) and amitriptyline treatment groups (treated with 39.06, 12.78, 156.25, 312.5, 625, 1250 and 2500 μg/ml of amitriptyline). MTT method was used to assay the cytotoxic effects of amitriptyline at 24 and 48 hours. The data were analyzed by one-way analysis of variance. Treatment with 39.06 and 78.12 μg/ml of amitriptyline for 24 hours had no significant effect on the viability of Hek-293 cells, but treatment with 156.25 μg/ml and higher concentrations of amitriptyline significantly reduced the viability of Hek-293 cells. Treatment of cells for 48 hours showed a significant reduction in cell viability at all concentrations. Amitriptyline has cytotoxic effects on normal human embryonic kidney cells and these effects depend on the dose and duration of treatment. The findings of this study can be of significant importance in terms of the side effects of amitriptyline consumption on normal cells of the human body.
Developing an empirical model for climate change adaptation in river management planning using DPSIR framework at Nabaganga river of Narail district, Bangladesh
Authors: Biswas Sabnil , Rahman M. Aminur Rahman , Mojumdar Shoumik
Published: February 2024

This study investigated the integration of ecosystem services and climate change adaption in river management planning in Bangladesh. The research was carried out in the selected villages with high vulnerability to climate change, namely Lohagara, Kalachandpur of Lohagara upazilla, Gazirhat of Kalia Upazila, and Narail. The survey was conducted by collecting data from both primary and secondary sources. For collecting primary data, different methods had been adopted including informal interviews, a semi-structured questionnaire survey and Focus Group Discussion (FGD). The present study modified the DPSIR framework to add connection that allows for the integration of ecosystem services and climate change responses in a future management plan. In this study, temperature and precipitation, changes in water level of the river from 1982 to 2020, rainfall pattern from 1984-2021 and yearly salinity level series of the river from 2014-2021 were analyzed for assessing the climate change impact on the river ecosystem. The changes in fish species diversity were also interpreted in this study and observed that 41 species were available in 2014 but now it has been reduced to 37 species. Some salinity tolerant species were found to be available recently due to salinity intrusion. In this study, the present river management practice was compared with community perception by SOWL analysis. The empirical model applied in this study is intended to support adaptation planning and monitoring and can not only be used in Nabaganga River but also in other vulnerable riverine ecosystems to climate change in Bangladesh.
The effects of berberine hydrochloride on the bone quality in methamphetamine-addicted rats after 3 weeks of withdrawal
Authors: Yahyaei Fariba , Behrad Samira , Ghorbani Raheb , Khaksari Mehdi , Sadat Afraz Elham
Published: February 2024

Animal studies have shown that berberine hydrochloride reduces osteoporosis and has anti-inflammatory effects. The aim of this study was to evaluate the therapeutic effect of berberine hydrochloride on the quality of new bone and the severity of bone inflammation in methamphetamine-addicted rats after 3 weeks of withdrawal. A total of 21 male Wistar rats were divided into 2 groups: control (n = 7), methamphetamine (n = 7), and methamphetamine + berberine groups (n = 7). The 2 addicted groups received water-soluble methamphetamine up to 12 mg/kg for 2 weeks. Subsequently, they were abstinent for 3 weeks. Only 1 group received 100 mg/ kg/ day of berberine. After 3 weeks, the mandibular bone of rats was removed for histopathological evaluation of the severity of inflammation and the quality of new bone via hematoxylin and eosin (H&E) staining. Data were analyzed using Shapiro-Wilk and Mann-Whitney U tests. The software used was SPSS version 24, and the significance level was 0.05. The new bone formation was more mature in the methamphetamine + berberine group than in the methamphetamine group (P < 0.05). The bone inflammation was more severe in the methamphetamine group than in the methamphetamine + berberine group (P < 0.05). Because of the beneficial effects of berberine on the mandibular jaw, it can reduce the oral side effects of methamphetamine addiction.
Status and vulnerability of Acropora spp. assemblages at the Egyptian coasts of the red sea
Authors: Ismail Mohamed , Aminur Rahman M.
Published: February 2024

In the Red Sea, the availability of information about the status of Acropora spp. assemblages is more restricted, where a few comprehensive or even preliminary studies were conducted on the genus Acropora at this area, especially at the Egyptian coasts. Accordingly, our goal focused on the assessment of the status of genus Acropora assemblages at the Egyptian coasts of the Red Sea and addressing the main keystone species of Acropora at this area. Three sites at the Gulf of Aqaba, located in Ras Muhammad National Park in addition to two sites at the Red Sea proper (Hurgada and Marsa Alam) were selected to conduct the study during 2016. The line intercept transect methodology was used to estimate the cover of Acropora assemblages. Samples from different colonies of Acropora were collected for further analysis of the micromorphology of coral’s exoskeletal structures. The study revealed that there were 16 common species of Acropora at the study sites. Also, the results indicated that Gulf of Aqaba had the higher benthic cover of Acropora assemblage than southern ones. On the other hand, some of the near threatened species of Acropora, proposed by IUCN Red List, showed high benthic cover compared to other species. The study concluded that more than 50% of the Acropora species at the Egyptian coasts of the Red Sea were threatened or vulnerable to different environmental perturbations according to IUCN criteria. Consequently, the coral reefs at the Gulf of Aqaba may represent a refugium for endangered species at the Red Sea.
Development of winter wheat leaf blotches depending on meteorological conditions
Authors: Švarta Agrita , Bimšteine Gunita , Kaņeps Jānis
Published: February 2024

Tan spot (caused by Pyrenophora tritici-repentis) and Septoria tritici blotch (caused by Zymoseptoria tritici) are the most widespread winter wheat leaf blotches in Latvia. Precipitation and air temperature are important factors in the development of fungal diseases. The aim of the present research was to clarify the development of leaf blotches in winter wheat depending on meteorological conditions. A field trial was conducted at the Research and Study farm “Peterlauki” (Latvia) of the Latvia University of Life Sciences and Technologies in 2018–2021. The disease impact during the vegetation periods was estimated by calculating the area under the disease progress curve (AUDPC). The severity of leaf blotches in winter wheat leaves differed significantly during the four vegetation seasons. Tan spot was the dominant disease in 2018, 2019 and 2021 (respectively 2.12%, 18.7% and 4.1% in the untreated variant at the time of grain ripening (GS 75–79)), when weather conditions were dry and warm. The first symptoms of tan spot were observed already at GS 31–32, but rapid development of the disease began at the time of grain ripening (GS 73–79 depending on year). In such conditions, Septoria tritici blotch started later and its progression was slower than that of tan spot. Septoria tritici blotch dominated in 2020 (11.4% in the untreated variant at GS 75–79), when precipitation amount was high. The first symptoms were observed at GS 31–32, but rapid disease development started at GS 73 (2.7% in untreated variant) which coincided with rainfall. The differences in average AUDPC values during investigation years fluctuated within a range of 13–142 units for tan spot and 1–57 units for Septoria tritici blotch. The research was supported by the EIP–Agri project “The development of the decision–making support system for restriction of the diseases, affecting leaves and ears of winter wheat”.
Danske gymnasieelevers multimodale anvendelse i fysiske og digitale læringsrum
Authors: Jensen Lasse , Nielsen Michael Juul
Published: February 2024

Formålet med artiklen er at undersøge danske gymnasieelevers anvendelse af digitale læremidler. Undersøgelsen tager udgangspunkt i observationer og interviews med klasser fra de fire gymnasiale retninger; HHX, STX, HF og HTX med henblik på, at udvikle designprincipper der understøtter elevers multimodalitet i digitale læremidler. Danske gymnasieelever udviser på baggrund af en rig individualiseret medieøkologi, en høj grad af multiplexing og singletasking i anvendelse af digitale læremidler, der gør at Illeriis didaktiske trekant er udfordret i traditionel forstand. Ud af undersøgelsen træder fire digitale elevtyper frem, som adskiller sig fra traditionelle elevtyper ved bl.a. at anvende digitale læremidler til transformation af de læringsrum de befinder sig i. Artiklen diskuterer på baggrund af undersøgelserne, hvordan elevadfærden kan styrke fællesskaber i transformerende læringsrum, hvordan elevers multimodale blik kan kultivere Expert-like Learner kompetencer og hvordan den nye digitale virkelighed understøtter de traditionelle læringsteoretikere, som den danske gymnasieskole bygger på
Undervisningsdifferentiering som en praksis på læreruddannelsen?
Authors: Böwadt Pia Rose , Cortsen Rikke Platz
Published: February 2024

Med afsæt i, at undervisningsdifferentiering er et emne på læreruddannelsen og en kommende praksis for de studerende i deres virke som lærere, er artiklens fokus kvaliteten af undervisningsdifferentiering i læreruddanneres egen undervisningspraksis, som underviserne selv beskriver det. Artiklen handler om, hvordan læreruddannere rapporterer, de forstår og praktiserer undervisningsdifferentiering i deres egen undervisning – også med henblik på de studerendes forskellighed. Undervisernes måde at forholde sig til undervisningsdifferentiering kan med et andenordensdidaktisk sigte tjene som eksempel for de studerendes kommende undervisning. Artiklens empiri er hentet fra en spørgeskemaundersøgelse blandt læreruddannere på Københavns Professionshøjskole. På baggrund af en analyse af kvantitative såvel som kvalitative data peger artiklen på en forskellighed i, i hvor høj grad læreruddannerne angiver at praktisere undervisningsdifferentiering, og om det overhovedet opleves som deres opgave. Artiklen konkluderer, at man med fordel kan arbejde med at integrere systematisk arbejde med undervisningsdifferentiering for læreruddannere.
Nye lærerstuderendes forståelser af kvalitet i undervisning
Authors: Rasmussen Hanne Fie , Agergaard Karsten , Hansen Lotte Holk
Published: February 2024

Nye lærerstuderendes forståelser af undervisningskvalitet kan blive en barriere for at udvikle deres lærerfaglige opmærksomhed. Dette studie undersøger deres forståelser af undervisningskvalitet, og hvilke praksisteorier de trækker på for at udføre kvaliteterne i praksis. Vores empiri består af studerendes beskrivelser af undervisningssituationer og deres samtaler om disse, som kommer fra et gennemført Learning to Notice-forløb, hvor de studerende observerede videooptagelser af undervisningspraksis fra folkeskolen. Vi har udledt udsagn om undervisningskvalitet og praksisteorier fra empirien og analyseret dem i forhold til både tre kvalitetsområder ved undervisning og ni kvalitetskriterier for områderne. Vi finder, at de nye lærerstuderende forstår kvalitet som lærerhandlinger, der fremmer elevernes præstationer, og ikke om handlingerne er moralske, eller om indholdet har et værdigt formål, samt om eleverne anstrenger sig og retter sig mod indholdet. I praksisteorierne er de studerende optaget af, at lærerhandlinger understøtter måder, eleverne kan arbejde med indholdet på, og at læreren skal respondere på eleverne i undervisningssituationer.
Kvalitet i partnerskaber mellem folkeskole og læreruddannelse
Authors: Albrechtsen Thomas R. S. , Carlsen Dorthe , Gammelgaard Ole , Hachmann Roland
Published: February 2024

Formålet med artiklen er at redegøre for og diskutere, hvordan idéen om partnerskaber mellem folkeskole og læreruddannelse har udviklet sig historisk, med udgangspunkt i nogle få eksempler og med særligt blik på idéen om opbyggelsen af universitetsskoler. Artiklen bidrager således med et overblik over nogle tendenser i partnerskabsdannelser som et særligt kriterium for læreruddannelse af høj kvalitet. Vi zoomer i artiklen ind på den partnerskabsmodel, vi har udviklet på UCSYD, hvor vi med idéen om universitetsskoler søger at favne flere aktører og forskellige vidensformer, og som centrerer sig om skabelsen og udviklingen af didaktiske undersøgelsesfællesskaber, der bidrager til både forskning, uddannelses- og skoleudvikling.
Business Intelligence applied to inventory management: case of a small retail company
Authors: Aguiar Clara Gouveia , Alcalá Symone Gomes Soares
Published: February 2024

Business Intelligence (BI) is a set of techniques that assist organizations in making data-driven decisions, enabling interactive access to information, often in real-time. In this way, its application provides precise business analyses, contributing to goal tracking, results projection, identification of opportunities, and anticipation of risks. Therefore, the objective of this work is to create a BI solution using data extracted from an Enterprise Resource Planning (ERP) to assist inventory management in a small-scale retail company specializing in party supplies. Factors such as shelf stockouts and inconsistencies between the system and the real environment have driven the development of this project. Facing ineffective inventory management and limited access to strategic information, a BI solution was developed in the company following steps such as problem analysis, data selection, extraction and processing, database modeling, BI implementation, and testing and evaluation. Thus, two focused dashboards were developed, one for the overall inventory report and another for monitoring safety stock. Through these dashboards, it is possible to assess inventory levels and product movement, devise strategies based on historical analyses, and identify the need to issue new purchase orders by product. The achieved results were positive, highlighting significant improvements in inventory management effectiveness and consolidating decision-making processes through quick and interactive access to strategic information.
The importance of preservation, conservation and recovery of natural resources in the Manaus Sustainable Development Reserve to halt warming and climate change in the Amazon
Authors: Da Silva Antonio Jorge Barbosa , De Souza Maria Cláudia da Silva Antunes , Da Silva Ygor Felipe Távora
Published: February 2024

The main purpose of this research is to highlight the importance of preserving, conserving and recovering natural resources in the Manaus Sustainable Development Reserve to halt warming and climate change in the Amazon. In light of this, the methodology applied to achieve the proposed objectives consists of using contributions from the literature on the preservation and conservation of natural resources in the Tupé RDS. Furthermore, the approach applied is bibliographic, enriched with legal provisions and jurisprudential understandings applicable to the species, with a descriptive and explanatory procedure, with a data source from legal literature, after carrying out a survey of references relevant to the research. To describe the proposed results, the approach used is qualitative and quantitative. The construction of the work highlights the importance of preserving and conserving the Tupé Sustainable Development Reserve, located in Manaus, to encourage initiatives that prioritize the preservation of natural resources and that respect current legislation. At the end of the research, the importance of the topic was highlighted, as it will bring together not only academic aspects, but also government policies. Another aspect of the work was to point out and contribute to the geopolitical understanding of the forms of socio-environmental intervention, which is evident with the structuring of the Tupé Sustainable Development Reserve as a Sustainable Use Conservation Unit.
Exploring the Impact of Employer Branding on Intention towards Job Application: The Mediating Role of Social Media
Authors: Khan Ryan Basith Fasih
Published: February 2024

Research on Generation Z's career preferences and expectations is new because they are new to the labour market and have different personalities and interests than previous generations. This requires a different approach to recruiting and selecting jobs. HRD needs to understand the factors that motivate Generation Z to work and adjust the work environment to maintain its presence in the workforce. This research involved 172 respondents from Islamic universities in East Java. This study aims to explore the effect of employer branding on the intention to apply, which is mediated through social media. This study also uses SEM-PLS to answer the hypothesis. The finding is that Employer Branding can influence intention in applying for a job, but social media is not able to mediate the effect of employer branding on intention to apply; social media is at the same time new as an intervening variable.