bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of the Preservice Science Teachers’ Astronomy Conceptions via Planetarium Trip
Authors: ÖZCAN Hasan , YILMAZ Şirin
Published: June 2018

Today’s educational and teaching activities

comprise of the planned learning environments, including the informal learning

environments and the field trips planned to be made to these environments

(planetarium, museum, zoo, etc.), continuing for the whole life in a manner

using all the available resources. In such activities, the teachers play a key

role. The objective of the study within this context is to reveal the

definitions and knowledge levels of the preservice science teachers (PSTs),

including their opinions on planetarium and the contribution to science and

astronomy education with preliminary and final tests with regards to the trip

made to the planetarium, which is accepted to be as an environment for informal

learning environments. The preliminary test of the study, where the phenomenological pattern was used as one of the

qualitative research methods was fulfilled with 29 preservice science teachers

(24 female, 5 male), while the final test process was fulfilled with 44

preservice science teachers (33 female, 11 male). The Planetarium Trip Survey Form

(PTSF), developed by the researchers and comprising of open-ended questions was used as the preliminary-final tests. At

the end of the research, positive changes were observed on the concepts of

planetarium trip and the astronomy for the preservice science teachers, as well

as providing suggestions for the respective research and the researchers, who

plan to carry out similar studies.
Kimya Öğretmenlerinin Eğitimde Ölçme ve Değerlendirme Süreçlerinde Yaşadıkları Problemler ve Yetersizlikler
Authors: ŞENEL Selma , PEKDAĞ Bülent , GÜNAYDIN Serpil
Published: June 2018

Nitelikli insan gücünün yetiştirilebilmesi ve

eğitim yatırımlarının yerine ulaşması için öğrenci başarısının ölçülmesi ve

ölçme sonuçlarının değerlendirilerek, eğitimin sonraki sürecinin belirlenmesi

gerekmektedir. Bu noktada öğretmenlerin ölçme ve değerlendirme (Ö&D)

konularındaki bilgi, tecrübe ve yeterlilikleri belirleyici bir rol

oynamaktadır. Bu araştırmada Kimya öğretmenlerinin Ö&D alanında yetersiz

hissettikleri konuları ve bu alanda yaşadıkları problemleri ortaya koymak

amaçlanmıştır. Uygulamadaki Ö&D sorunlarına, kavram ve uygulama

yanılgılarına odaklı derinlemesine bir analiz yapmak amacıyla nitel bir

yaklaşım benimsenmiştir. Her biri 6 öğretmenden oluşan iki odak grup görüşmesi

yapılmıştır. Veriler, içerik analizi ile çözümlemiştir. Verilerin analizi

sonucunda, öğretmenlerin özellikle soru yazma ve alternatif Ö&D araçlarını

kullanma konularında yetersizlik duydukları sonucuna ulaşılmıştır. Ö&D

alanında yaşanan temel problemler ise; iyi bir ölçme yapabilmenin uzun ve güç

bir süreç olması, eğitim sisteminin Ö&D’ye dayatmaları, kaliteli soru örnekleri/havuzlarının olmaması ve

hizmet içi eğitimlerin etkisiz olması olarak bulunmuştur. Araştırma sonucunda

uygulamaya dönük hizmet içi eğitimler ve değişen öğretim programlarıyla

birlikte güncellenebilecek eğitim materyallerinin tasarlanması yönünde öneriler

sunulmuştur. 
The Effects of Centralization of Islamic Higher Education in Egypt: From the Medieval to the Modern
Authors: Sabrin Mohammed
Published: June 2018

This study compared how, over time, the centralization of Islamic Higher Education affected educational quality, probity of school management and general levels of and appreciation for knowledge. This research involved comparing characteristics of Egyptian Islamic Higher Education at three pivotal points in time: the early medieval period (623-1300s C.E.); the 15th century; and the period of British and French colonization (the 19th and 20th centuries). The logic behind choosing these particular time periods for comparison was that they represented times of significant centralization/decentralization of Egyptian Islamic Higher Education. Upon analysis of the effects of centralization and de-centralization, it has been found that the centralization of Islamic Higher Education in Egypt has had negative effects. It was found that, over time, the centralization of Islamic Higher Education played a central role in decreasing educational quality, increasing corruption, and decreasing general levels of and appreciation for Islamic knowledge.
Maternal satisfaction with delivery services at tertiary university hospital in upper Egypt, is it actually satisfying?
Authors: Sayed Waleed , Abd ElAal Diaa Eldeen M. , Mohammed Hazem S. , Abbas Ahmed M. , Zahran Kamal M.
Published: June 2018

Background: Maternal health has therefore become an important aspect of policy and planning for healthcare, as reflected by its inclusion as the fifth Millennium Development Goal (MDG). The objective of the present investigation was to determine the maternal satisfaction towards delivery services at Women's Health Hospital, Assiut University, Upper EgyptMethods: A cross sectional study was performed. The study was conducted during February- April 2016 on a sample of 400 delivering mothers; the data were collected using a semi-structured questionnaire and analyzed by SPSS version21. Statistical tests were used, and significance level was taken at p-value <0.05.Results: A total of 400 delivering mothers were interviewed, of which 67.0 % of the respondents were between the age group of 20-30, 76.75 % were from rural areas, 48.0%were illiterate, 86.75% were house wives and 46.0% belonged to the income group of less than 500 EGP. The findings of the study showed that the overall maternal satisfaction level with the delivery services rendered at the hospital was 78.5%, while 21.5% were dissatisfied. Furthermore, satisfaction with the delivery service was found to have a significant association with the age of the respondents and educational level of the respondents. Moreover, results suggest that women are satisfied with the communication factors, interpersonal behavior, good management, and general satisfaction. Women were least satisfied with privacy sensation during hospital stay and obligatory blood donation.Conclusions: Although most participants were satisfied by the delivery service provided to them during delivery, Dissatisfaction by a minority group resulted in a limited ability of communication with mothers, lack of privacy sensation during hospital stay and obligatory blood donation. Thus, mechanisms should be developed to increase maternal satisfaction in our hospital.
Influence of socio-demographic variables on the choice of contraceptives among women attending ANC unit at specialist hospital Sokoto, Sokoto State, Nigeria
Authors: Sabo Aliyu Sokoto , Yakubu Lawali , Luba Aliyu Alkammawa , Ya`u Samira L. , Bakare A. T. , Fatima Muhammad , Zayyanu Isah M. , Zulkiflu Musa A.
Published: June 2018

Background: A contraceptive choice that couples make is a key component of the Sustainable Development Goal agenda and a major contributor to national health. In spite of the importance of increased contraceptive uptake among couples of reproductive ages, meeting the reproductive health rights of women remains an issue due to multi-faceted obstacles within complex environments. The issues which impact women’s reproductive health rights in relation to contraception relate to availability, accessibility, affordability, literacy, tradition, and culture. This study explores the influence of socio-demographic data on the choice of contraceptives among women who are accessing family planning services at a Specialist hospital, Sokoto-Nigeria.Methods: A cross sectional study was used in this quantitative research to generate data on contraceptive choices of women within the reproductive age (18-49 years) who are accessing family planning services at Specialist hospital, Sokoto. A structured questionnaire was used to elicit information from 352 respondents who were randomly sampled at a Specialist hospital, Sokoto-Nigeria. Data was analyzed using SPSS version 20.0. Descriptive statistics, correlation and regression analyses were used in the data analyses.Results: The findings of this study established age, occupation and level of education to be related with the usage and choice of contraceptives among women attending family planning unit at a Specialist hospital in Sokoto.Conclusions: The result of the study indicated that the socio–demographic data of the respondent, has a significant role in the choice of contraceptives among the women attending family planning unit of Specialist Hospital Sokoto.
Decision to incision interval for emergency caesarean section and postoperative outcomes in a resource limited rural Kenyan public hospital
Authors: Kamotho David , Pertet Anne M. , Ogwayo Isaac
Published: June 2018

Background: Standard guidelines recommend that delivery by caesarean section should be ideally initiated within 30 minutes of the decision to operate to avoid maternal and foetal compromise in labour. The purpose of this study was to investigate the extent to which these guidelines can be achieved in limited resource hospital.Methods: Authors used a secondary data from 330 patient's files of women who had a caesarean section from December 2013 retrospectively to January 2012.Results: The main indications for caesarean section was obstructed labour (18.5%) for mothers and foetal distress (6.4%). Though 74% of the mothers gave consent to be operated within the 30-minute guideline, only 3% were prepared for operation within this period. Only 24% of the caesarean sections were conducted within one hour after the decision was made for the operation. About 38% of the women, and 30% of the babies developed complications after the caesarean section.  Haemorrhage was the leading complication in mothers while the main complication for babies was babies with an Apgar score of 5 and below.Conclusions: The 30- minute recommended guideline for caesarean section was not achieved, and there was evidence of adverse post-operative outcome as a result of not meeting the global standards.
Comparative evaluation of simultaneous administration of mifepristone and misoprostol; and misoprostol alone for induction of second trimester abortion
Authors: Jain Ankita , Agarwal Arpit
Published: June 2018

Background: The present study was conducted with the aim to assess the safety and efficacy of misoprostol alone and misoprostol with simultaneous mifepristone for second trimester termination of pregnancy.Methods: The study was conducted on 160 cases, divided in two groups of 80 cases each. In the study group 200 mg mifepristone and 200 μgm misoprostol given together on admission followed by miso every 3 hrs upto a maximum of 8 doses or until the abortion occurs, whichever occurs early. In the control group only miso was given in the same dose regime. If abortion did not occur within this duration it was considered failure of method. The results were analysed.Results: The success rate in first regimen was 98%. Mean induction abortion interval was significantly shorter in the study group, 8.62±1.96 h as compared to 14.5±3.01 h in the control group. The mean dose of the misoprostol required was significantly less in study group. The side effects like nausea, vomiting, fever, abdominal cramps, diarrhoea were observed more in control group (30%) in comparison to study group (12.1%).Conclusions: Mifepristone with simultaneous misoprostol is better than misoprostol alone and there is no need to wait for 24 hr after mifepristone for administration of misoprostol.
A prospective study of fetomaternal outcome in patients of pregnancy with jaundice in tertiary care centre
Authors: Arora Monica , Verma Suniti , Desai Ranjana , Sehra Ram Narain
Published: June 2018

Background: The objective of the study was to study the incidence of jaundice, biochemical alterations, Fetomaternal outcome and various liver pathologies of pregnant patients with jaundice.Methods: This was a prospective observational study conducted in Dr S N Medical College Jodhpur, Rajasthan, India from June 2014 to February 2016. Total fifty pregnant patients with clinical jaundice and prodromal symptoms of hepatitis were included in study.Results: Out of 40,398 deliveries in our hospital, 50 cases of jaundice were identified giving an incidence of 1 in 808 (0.12%). Most common cause of jaundice in pregnancy in our set up was viral hepatitis i.e. 13 cases (26%) were HEV+ and 1 case (2%) came out to be HAV+. Serum LDH levels were raised in 36% of patients. Maximum no. of patients had their serum AST/ALT levels in the range of 100-1000 IU/ml (54%). Out of 52 births (2 twins) 34 were live births (65.38%) and rest were either SB or IUFDs. Most common causes of mortality in patients were Septicemia, MODS, DIC (25%) followed by HELLP syndrome and HEV+ viral hepatitis equally (16.67%). Maximum no. of patients with jaundice suffered from postpartum haemorrage and septicemia (60%).Conclusions: Most common cause of jaundice in pregnancy in our study was viral hepatitis. Public awareness about the various routs of transmission of different types of infective hepatitis, improving sanitary conditions and habits, health education of preventive measures can help in reducing the burden of jaundice in pregnancy.
Efficacy and safety of oral mifepristone for cervical priming and induction of labor in term pregnancy
Authors: Gupta Abhilasha , Verma Aruna , Madan Iti , Kashyap Monika
Published: June 2018

Background: The objectives of the study was to assess the efficacy of mifepristone in priming the cervix/inducing labor over next 96 hrs in term pregnancy.Methods: In this single blind randomized controlled trial 200 women with term pregnancy beyond 39 weeks and Bishop’ score <6 were randomly allocated into two groups. Tab Mifepristone 400 mg orally was given to women in study group (n=100) and no intervention in control group (n=100). On follow up one case was lost in control group. All women were observed for change in the bishop’s score or onset of labor in next 96 hrs. If Bishop’s score was <6, the choice of induction was left on the clinician/patient.Results: Mean induction to delivery interval, duration of active phase and improved Bishop score were 79.35±53.43 hr, 2.47±1.23 hr, 6.68±1.69 for study group versus 148±65.66 hr, 3.09±1.45 hr, 5.8±2.15  for control group (p value is <0.001) respectively.  Seventy one (71%) women in study group and 39 (39.3%) women in control group delivered vaginally within 96 hrs without any need of augmentation. There were 9 (9%) caesareans in study group and 24 (24.2%) caesareans in control group but no instrumental delivery in both groups. There was no statistically difference in perinatal outcomes between two groups.Conclusions: Mifepristone is an effective drug for cervical ripening and initiation of labor when given in term pregnancy beyond 39 weeks with poor Bishop’s score (<6) and appearing to reduce need for other agent for augmentation of labor.
“Free radical induced oxidative stress” (frios) parameters: key to reduce feto-maternal mortality in high risk pregnancies
Authors: Chauhan Shalini , Pandey Kiran
Published: June 2018

Background: ROS plays role during pregnancy and normal parturition and in recurrent pregnancy loss, initiation of preterm labor, anaemia, preeclampsia, eclampsia, Intrauterine growth retardation. Elevated oxidative stress is found in term infants with fetal distress and in preterm infants. With this background this study was conducted to evaluate the role of FRIOS (free radical induced oxidative stress) in reducing feto -maternal mortality in high risk pregnancies in District Kanpur.Methods: This prospective study was conducted on pregnant women at high risk attending department of Obstetrics and Gynaecology, GSVM Medical College, Kanpur after taking permission from the institutional ethical committee. Informed consent was obtained from all patients. Investigations were carried out to measure oxidant level of Malonaldialdehyde (MDA) enzyme & to measure anti oxidant Super Oxide Dismutase (SOD) enzyme. Levels of these enzymes were compared between normal & each high risk sub groups separately. SPSS software was used for statistical analysis and suitable tests were applied.Results: The mean value in study group was highest in severely anaemic patients (8.53±1.398 Nmoles/ml of plasma) followed by pre eclamptic & eclamptic patients (8.33±1.355 Nmoles/ml of plasma). The mean levels of in study group was lowest in pre eclamptic & eclamptic patients (0.394±.191 u/mg of protein) followed by pre term patients (0.413±0.141 u/mg of protein). Significant difference between MDA enzyme levels in control group and all sub groups of study group was found.Conclusions: Measurement of Malonaldialdehyde (MDA) & Super Oxide Dismutase (SOD) enzymes at an earlier stage can be a valuable tool for early diagnosis, so that we can timely intervene & improve the maternal outcome.
A study to explore living- in experiences of women with spontaneous abortion at selected hospital, Ambala, Haryana, India
Authors: Kharb Renu , Sheoran Poonam
Published: June 2018

Background: The purpose of this study was to explore living-in experiences of women with spontaneous abortion in terms of financial, social, psychological, physical trauma and any other aspect expressed by the women.Methods: Mixed Method approach with method triangulation research design (concurrent QUAN + QUAL) was used to assess the living- in experiences of 12 women with spontaneous abortion selected using criterion sampling. Data collected through clinical record review and interview technique by using sample characteristics Performa, Perinatal Grief Scale, and open ended interview guide. Audio recording of the interviews was done.Results: Mean score of Perinatal Grief scale was 100 and scores ranged from 79- 129. Most of the women (91.66%) indicated possible psychiatric morbidity. Findings revealed that the mean percentage was higher in the area of active grief (83.53%) and least was in the area of despair (48.18%). A total of 4 themes and were identified from the analysis of qualitative data, major themes emerged were pregnancy expectations and wishes, greater the joy, more painful the crash, after the blue, fear and future expectations, burden on family, and support: a helping hand.Conclusions: Women undergone spontaneous abortion was disheartened and grieving for the child as they considered their fetuses as a full grown child. In study none of the women blamed themselves for the loss and were in a need of support from family members and health care providers.
Glycated haemoglobin versus oral glucose tolerance test in screening for gestational diabetes mellitus
Authors: Arthy S. , Arun I.
Published: June 2018

Background: Glycated haemoglobin (HbA1c) has been documented as an easier, useful tool in diagnosis of diabetes and can be considered as a screening tool in GDM as compared to oral glucose tolerance test (OGTT) which has practical constraints like long waiting period in fasting, too many pricks and non-compliance to glucose load solution. The objective of the study was to find out the utility of HbA1c as a diagnostic tool when compared with OGTT in screening of GDM.Methods: A retrospective study was conducted at Sri Venketeswaraa Medical College, Hospital and Research Center, Puducherry including 500 antenatal women attending to the Department of Obstetrics and Gynaecology for their ante-natal checkup during the period from August 2016 to April 2018. HbA1c levels were estimated and ROC curve analysis was done to estimate sensitivity and specificity against gold standard OGTT.Results: The HbA1c levels among the study subjects varied from 4.3% to 8.2%. The mean HbA1c levels among those diagnosed as GDM by gold standard OGTT was 5.82±1.1% and among those without GDM was 5.13±0.7%. The area under the ROC curve was 0.773 (95% CI 0.732–0.814). An HbA1c cut-off value of ≥5.91% had sensitivity of 34.6% and Specificity of 98.2% in diagnosing GDM. An HbA1c cut-off value of ≥5.32% had sensitivity of 84.8% and specificity of 60.1% in diagnosing GDM.Conclusions: HbA1c levels cannot substitute OGTT in diagnosis of GDM. A higher specific cut-off HbA1c value of ≥5.95% is diagnostic of GDM.
A study of congenital anomalies in a tertiary care hospital in North East region, India
Authors: Devi Kangjam Radhesana , Devi R. K. Praneshwari , Priya Jyoti , Sanaton Ahanthembi , Singh Leimapokpam Roshan , Murray Lalhlimpuii
Published: June 2018

Background: Congenital anomalies are important cause of morbidity and mortality in newborns and are defined as structural and functional abnormalities including metabolic disorders present at birth. These defects are of prenatal origin resulting from defective embryogenesis or intrinsic abnormalities in the process of development and are associated with various risk factors.Methods: Our study is a cross-sectional study done at Regional Institute of Medical Sciences, Imphal over period of one and half years from May 2016 to October 2017. Aim of study was to find out incidence of congenital anomalies and proportions of different types of congenital anomalies. Outcome was studied in relation to maternal age, religion, parity, gestational age, sex of baby, outcome and birth weight of baby.Results: Total numbers of congenital anomalies were 91 out of 13658 births. Incidence of congenital anomalies was 0.66%. Most common congenital anomaly was cleft lip (17.6%) followed by CTEV (13.2%) and was more common among male term babies. These were most common in 18-24 years of maternal age group (34.1%) followed by 30-34 years (26.4%) and among women of parity P0-P2.Conclusions: Congenital malformations are a major cause of still births and infant mortality. A level II targeted scan should be done at 18-20 weeks to find out anomalies and reduce the prevalence. There should be widespread education in the community regarding the common congenital malformations, their outcomes and possible available modes of treatment.
A prospective comparative study on uteroplacental blood flow, cardiac function and pregnancy outcome in women with heart disease and normal healthy pregnant women
Authors: Mathuriya Gayatri , Gondiya Pooja , Jain Ashish K.
Published: June 2018

Background: Cardiac dysfunction in women with heart disease results not only in cardiovascular complication, but also lead to abnormal uteroplacental flow pattern, thus compromising normal growth and development of the fetus and contributing to complication of pregnancy. Our aims include, study the distribution of the type of heart diseases, Grading of the subjects according to NYHA classification, to study the cardiovascular and uteroplacental Doppler flow pattern and their obstetrics and fetal outcome in heart diseases subjects and controls groups.Methods: This was a case control Prospective Comparative Study of 54 cases with Heart Diseases (cases) and 50 cases of normal healthy pregnant (control) admitted in Obstetrics and Gynaecology department.Results: Our study shows the correlation of abnormal ECHO and uteroplacentation flow, abnormal ECHO were seen in 20 cases out of them 11 cases (55%) had abnormal flow and 9 cases (45%) had normal flow In our study it was observed that among the cases with abnormal ECHO 37% (20 cases) 6 babies were handover healthy, 11 babies were went to nursery and 3 (5.56%) babies were IUD among control group ECHO of all the control were normal. And Uteroplacental Doppler flow was abnormal among 15 cases (27.7%) out of them 3 babies were healthy 9 babies went to nursery and 3 were IUD (5.56%) and colour doppler of control group is normal in most of the cases.Conclusions: Uteroplacental flow patterns of heart disease and healthy women relate these to cardiovascular parameters and to events and outcome in pregnant women .we will refine risk stratification that will lead to better prepregnancy counseling and may eventually improve treatment of these women by identifying the components responsible for pregnancy-related events in women with heart disease.
Model Pengembangan Industri Halal Food di Indonesia
Authors: Waharini Faqiatul Mariya , Purwantini Anissa Hakim
Published: June 2018

AbstractThe development of the halal industry will become more competitive with the involvement of the financial industry and sharia banking sectors. This study aims to explore the role of sharia banking in the development of halal food industry in Indonesia. The research method used is descriptive qualitative method with literature review. Based on the results of the analysis, it can be concluded that the role of sharia banking is not only limited to shariah-based financing which is riba (interest), maysir (uncertainty), and gharar (gambling), but also at all stages of production process (halal value chain management). Sharia banks play important role that can use to develop and improve the halal food industry. First on the halal control stage, the second on the logistics process and the last stage of halal verification.AbstrakPengembangan industri halal akan menjadi lebih kompetitif dengan keterlibatan dari sektor industri keuangan dan perbankan syariah. Penelitian ini bertujuan untuk mengeksplorasi peran perbankan syariah dalam pengembangan industri makanan halal di Indonesia. Metode penelitian yang digunakan adalah metode kualitatif deskriptif dengan telaah literatur. Berdasarkan hasil analisis, dapat disimpulkan bahwa peran perbankan syariah tidak hanya terbatas pada pembiayaan berbasis syariah yang bebas riba (bunga), maysir (ketidakpastian), dan gharar (perjudian). Akan tetapi juga pada seluruh tahapan proses produksi (halal value chain management). Peran penting yang dapat dilakukan perbankan syariah guna mengembangkan dan meningkatkan industri makanan halal, diantaranya dalam tiga proses halal integrity. Pertama pada tahap pengendalian halal, kedua pada proses logistik dan terkahir tahap halal verification.
Pengaruh Kualitas Pelayanan dan Corporate Social Responsibility Terhadap Citra Perusahaan
Authors: Nurjanah Risna , Mulazid Ade Sofyan
Published: June 2018

AbstractThis research aims to analyze the quality of service and corporate social responsibility BNI Syariah against corporate image in PT BNI Syariah Center, Jakarta. Sampling technique used in this research is convenience sampling method, then the data in the process by using multiple linear regression analysis method. Sample in this research is BNI Syariah Center customer, Jakarta amounts to 100 respondents. This research is a quantitative research and data analysis method using multiple liniear regression. The result of this research shows that partially the service quality and corporate social responsibility variables significantly influence the image of the company in syariah bank. Simultaneously the service quality and corporate social responsibility variables significantly influence the image of the company in syariah bank at the level of significance less than 0.05 or 5%.AbstrakPenelitian ini bertujuan untuk menganalisis kualitas pelayanan dan corporate social responsibility BNI Syariah terhadap citra perusahaan di PT BNI Syariah Pusat, Jakarta. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah metode convenience sampling. Kemudian data diproses dengan menggunakan metode analisis regresi linear berganda. Sampel dalam penelitian ini merupakan nasabah BNI Syariah Pusat, Jakarta berjumlah 100 responden. Penelitian ini adalah penelitian kuantitatif dan metode analisis data menggunakan regresi liniear  berganda. Hasil dari penelitian ini menunjukan bahwa secara parsial variabel kualitas pelayanan dan corporate social responsibility berpengaruh secara signifikan terhadap citra perusahaan di bank syariah. Secara simultan variabel kualitas pelayanan dan corporate social responsibility berpengaruh secara signifikan terhadap citra perusahaan di bank syariah pada tingkat signifikansi kurang dari 0,05 atau 5%.
Developing Massive Open Online Course (MOOC) : Need Analysis of Teaching Materials for Madrasah English Teachers
Authors: Mustikasari Dewi Wahyu
Published: June 2018

The purposes of this study are (1) to recognize the textbooks or other teaching materials used by the Madrasah English teachers, (2) to identify their obstacles in preparing the teaching materials, (3) to analyze the teaching materials which can be developed in MOOC, (4) to analyze the teaching materials for MOOC which are related to the Indonesian curriculum, (5) to analyze their willingness of proffesional teaching development by joining MOOC. This study used a descriptive qualitative approach. Moreover, the subjects of the study were 3 English teachers of MTs Negeri Salatiga and 5 English teachers of MAN Salatiga. Observation, interview and documentation were used as the techniques of data collection. The results showed that (1) they used the textbooks from Ministry of Education (MOE), selected main handbooks, supplemenatary teaching materials from certain websites, (2) communicative competence as the main issue of content of textbook from MOE gave different challanges for them to prepare the teaching materials, (3) authentic materials were highly needed to be developed in MOOC, (4) characters building based-teaching materials needed to be developed too as those are the uniqueness of the Indonesian curriculum, (5) they had less interest to join MOOC as their way to develop their proffesional teaching development.Keywords: MOOC, English teaching materials, authentic materials, characters building
Efeitos do Aquecimento Global nas Estratégias de Projeto das Edificações por Meio de Cartas Bioclimáticas
Authors: Guarda Emeli Lalesca Aparecida da , Durante Luciane Cleonice , Callejas Ivan Julio Apolonio
Published: June 2018

Pensar nas consequências do fenômeno do aquecimento global tem ganhado importância mundial, inclusive no ambiente construído. O presente trabalho tem por objetivo analisar as estratégias passivas de projeto por meio de cartas bioclimáticas para as das Zonas Bioclimáticas (ZB) 5, 6, 7 e 8 do estado de Mato Grosso. Para o estudo foi considerado o cenário de emissões A2, considerado como pessimista pelo Quarto Relatório (AR4) do Painel Intergovernamental sobre Mudanças Climáticas (IPCC). A metodologia consiste de três etapas: i) caracterização do clima e bioclima das ZB; ii) elaboração dos arquivos climáticos futuros (2020, 2050 e 2080) por meio do método “morphing” e a ferramenta Climate Change World Weather Generator (CCWorldWeatherGen) e iii) elaboração das cartas bioclimáticas por meio do software Analysis BIO com vistas à obtenção das horas anuais demandadas pelas estratégias passivas de projeto. Os resultados apontam para aumento das temperaturas médias anuais, alcançando valores superiores a 30,0°C e redução da umidade relativa do ar anual, atingindo valores inferiores a 60% em todas as ZB até o final do século. As estratégias de condicionamento artificial sombreamento terão maior demanda anual e as de massa térmica/aquecimento solar e ventilação reduzirão em todas ZB. As horas de desconforto por calor irão aumentar nas ZB 5, 6 e 7 e reduzirão na ZB 8. As horas de desconforto por frio irão reduzir em todas as ZB, até o final do século.
KALİTE FONKSİYONU GÖÇERİMİ YÖNTEMİYLE MÜŞTERİNİN MARKA ALGISININ ARTTIRILMASI : TAŞINABİLİR ŞARJ CİHAZLARI ÜRETEN BİR FİRMADA UYGULAMA
Authors: Gergin Zeynep , Akbaş Mert , Yurt Muhammed Furkan , Aktüre Alptuğ Ömer
Published: June 2018

Marka algısı müşterinin markaya dair yargılarını
kapsar ve üç alt faktör ile ölçülür. ‘İlişki değeri’ müşterinin markaya
bağlanmasına neden olan ölçütleri belirler. ‘Marka değeri’ markanın bilinirliği
ve kurumsal etik ile biçimlenir. ‘Algılanan objektif değer’ müşterinin üründen
aldığı toplam faydaya değer biçmesidir ve kalite ile ilişkilidir. Böylece
kalitenin arttırılması müşteri algısının yükseltilmesine hizmet edecektir.
Kalite Fonksiyonu Göçerimi, müşteri beklentilerini teknik özellikler ile
ilişkilendirerek, kalitenin beklentiler doğrultusunda iyileştirilmesini
sağlayan bir araçtır. KFG uygulamasıyla yapılacak kalite iyileştirmeleri
neticesinde marka algısının arttırılması da başarılacaktır. Bu çalışmada
taşınabilir şarj cihazları marka algısının arttırılması için KFG uygulaması
yapılmıştır. Geliştirilen anket satış elemanları ve tüketicilerden oluşan iki
farklı örneklem grubu tarafından cevaplanmıştır. Anket sonuçlarıyla müşteri
algısı değerlendirilmiş, KFG matrisi yapılandırılarak analiz edilmiştir. Mevcut
müşteri algısının üç alt faktör bazında açılımı ve iyileştirme önerileri
firmaya sunulmuştur.
Simulations and Modeling of Intermediate Luminosity Optical Transients and Supernova Impostors
Authors: Kashi Amit
Published: June 2018

Intermediate-luminosity-optical-transients (ILOTs) are stellar outbursts with luminosity between those of classical novae and supernovae. They are divided into a number of sub-groups depending on the erupting progenitor and the properties of the eruption. Many of the ILOTs sit on the slanted Optical Transient Stripe (OTS) in the Energy-Time Diagram (ETD) that shows their total energy vs. duration of their eruption. We describe the different kinds of ILOTs that populate the OTS and other parts of the ETD. We also stand on similarities between Planetary Nebulae (PN) to ILOTs, and suggest that some PNe were formed in an ILOT event. The high energy part of the OTS is reserved to the supernova impostors -- giant eruption of very massive stars. We show results of 3D hydrodynamical simulations of supernova impostors that expose the mechanism behind these giant eruptions, and present new models for recent ILOTs. We stand on the connection between different kinds of ILOTs, and suggest that they are powered by a similar source of energy -- gravitational energy released by mass transfer.
Engineering Cell Adhesion and Orientation via Ultrafast Laser Fabricated Microstructured Substrates
Authors: Babaliari Eleftheria , Kavatzikidou Paraskevi , Angelaki Despoina , Chaniotaki Lefki , Manousaki Alexandra , Siakouli-Galanopoulou Alexandra , Ranella Anthi , Stratakis Emmanuel
Published: June 2018

Cells take decisions on their responses depending on the stimuli received by the surrounding extracellular environment, that provides the essential cues at the micro and the nano-lengthscales required for adhesion, orientation, proliferation and differentiation. In this study, discontinuous microcones on silicon (Si) and continuous microgrooves on polyethylene terephthalate (PET) substrates were fabricated via ultrashort-pulsed laser irradiation at various fluences, resulting in microstructures with different roughness and geometrical characteristics. The topographical models attained were specifically developed to imitate the guidance and alignment of Schwann cells for oriented axonal regrowth, towards nerve regeneration. At the same time, positive replicas of the silicon microstructures formed were successfully reproduced, via soft lithography, on the biodegradable polymer poly(lactide-co-glycolide) (PLGA). The anisotropic continuous (PET) and discontinuous (PLGA replicas) microstructured polymeric substrates were assessed in terms of their influence on the Schwann cells responses. It is shown that the developed micropatterned substrates enable control over the cellular adhesion, proliferation and orientation and are thus useful to engineer cell alignment in vitro. This property could be potentially useful in the fields of neural tissue engineering and for dynamic microenvironment systems that simulate in vivo conditions.
Adaptation and Therapeutic Exploitation of the Plasma Membrane of African Trypanosomes
Authors: Quintana Juan F. , del Pino Ricardo Canavate , Yamada Kayo , Zhang Ning , Field Mark C.
Published: June 2018

African trypanosomes are an early branch in eukaryotic evolution and developed a unique endomembrane system as an adaptation to their parasitic life style. The key virulence mechanism of many pathogens is successful immune evasion to enable survival within the host, which is a feature requiring both genetic events and membrane transport in African trypanosomes. Intracellular trafficking not only plays a role in immune evasion, but also in homeostasis of intracellular and extracellular compartments and interactions with the environment. Significantly, historical and recent work has unravelled some of the connections between these processes and highlighted how immune evasion mechanisms associated with adaptations in membrane trafficking may have, paradoxically, provided specific sensitivity to drugs. Here we explore these advances in understanding the membrane composition of the trypanosome plasma membrane and organelles and provide a perspective for how transport could be exploited for therapeutic purpose.
Total Wrist Arthroplasty
Authors: Srnec Jason J. , Wagner Eric R. , Rizzo Marco
Published: June 2018

* There are limited motion-sparing salvage options for patients with pancarpal wrist arthritis. Total wrist arthroplasty is one option that has long been used in an attempt to preserve motion while relieving pain and wrist dysfunction; however, enthusiasm for the procedure has been tempered by high rates of complications.

* In an attempt to minimize or eliminate these complications, recent implants have been redesigned with a more semiconstrained arc of motion and ellipsoidal articulation. Furthermore, the distal component has undergone many different modifications to improve bone growth into the implant.

* Short-term small series have shown promising improvements in terms of the rate of complications as compared with previous-generation designs.
Optimal Multimodal Analgesia Treatment Recommendations for Total Joint Arthroplasty
Authors: Sah Alexander P. , Liang Kevin , Sclafani Joseph A.
Published: June 2018

* The opioid epidemic is an expanding crisis, and inadequate postoperative pain management can contribute to the growing problem.

* Multimodal pain management is effective in optimizing pain relief while minimizing complications and side effects.

* Improved pain management in the setting of hip and knee arthroplasty has generally led to improved outcomes and higher patient satisfaction.

* Pain management protocols are in constant evolution, and results may vary between providers. Well-performed studies are required to determine the most effective treatments.
Displasia cemento-óssea florida: relato de caso clínico
Authors: Silva Ellen Pereira da , Santos Luciano Cincurá Silva , Prado Fabio Ornellas
Published: June 2018

A displasia cemento-óssea florida é uma patologia que afeta preferencialmente o osso mandibular de mulheres negras acima de quarenta anos. Na maioria dos casos esta se caracteriza por ser assintomática, sendo apenas diagnosticada através de exames radiográficos. O presente artigo relata o caso de uma paciente leucoderma de 26 anos de idade, com lesões de displasia cemento-óssea florida, localizadas bilateralmente em mandíbula, e seu tratamento cirúrgico. Conclui-se ressaltando a importância do conhecimento clínico sobre essa patologia, pois esse entendimento será essencial para obtenção de um diagnóstico preciso e na elaboração de plano de tratamento adequado, proporcionando ao paciente melhor prognóstico.Descritores: Displasia Fibrosa Óssea; Cemento Dentário; Doenças Ósseas.
Assessing impacts of water regulations on alleviating regional water stress with a system dynamics model
Authors: Huang Huiping , Wang Jiangfeng , Han Yuping , Wang Lei , Li Xinsheng
Published: June 2018

Many areas around the world are faced with water scarcity and virtual water can provide ways to resolve the problem. This paper presents a comprehensive water system based on a system dynamics model to assess how water regulations from the viewpoint of virtual water affect the regional water stress index in the Haihe River Basin, China. The results show that green water absorption, blue water consumption, virtual water flow, and water use efficiency play important roles in the water resources system. Water stress can be relieved by improving the infiltration coefficient, irrigation efficiency, industrial water use efficiency, and virtual water import.
Evaluation of a Norwegian-developed ELISA to determine microcystin concentrations in fresh water
Authors: Botha C. J. , Laver P. N. , Singo A. , Venter E. A. , Ferreira G. C. H. , Rösemann M. , Myburgh J. G.
Published: June 2018

Cyanobacteria are known for their extensive and highly visible blooms in rivers or dams in Africa. One of the most important cyanobacteria is Microcystis aeruginosa which can synthesise various microcystins that may affect the health of humans and animals. Accurate and efficient detection of microcystins in water is thus important for public and veterinary health. Two enzyme-linked immunosorbent assays (ELISA), a commercially-available ELISA kit (Abraxis) and a newly-developed Norwegian ELISA (putatively cheaper and more robust) were used to detect microcystins in fresh water in South Africa. Water samples were collected monthly at two sites, the Hartbeespoort Dam and a crocodile breeding dam. Extremely high microcystin concentrations (exceeding 360 μg L−1) were detected in the Hartbeespoort Dam during January 2015, whereas the microcystin concentrations in the crocodile breeding dam peaked during March–April 2015. Both ELISAs were positively correlated when analysing water samples ‘as is’ and following resin adsorption and methanol extraction. However, following resin adsorption and methanol extraction of the water samples, the correlation between the two assays was much stronger. These results suggests that the two ELISAs provide comparable results. If the Norwegian-developed ELISA can be packaged and made available as a user-friendly kit, it could be used successfully in surveillance programmes to monitor microcystin concentrations in fresh water bodies in Africa.
Synthesis of 3-furanyl-4,5-dihydroisoxazole Derivatives via Cycloaddition and their Antibacterial Evaluation
Authors: de Andrade Danin Barbosa Gabriela , de Aguiar Alcino Palermo , de Carvalho Erika Martins , da Rocha Nogueira Joseli Maria
Published: June 2018

Background: Antimicrobial resistance is a major threat to human health. So this manuscript
describes the synthesis of five different 3,5-disubstituted 4,5-dihydroisoxazoles with antimicrobial
activity.

Methods: They were obtained from nitrile oxide cycloaddition derived from 2-furaldehyde and 5-
nitro-2-furaldehyde to different dipolarophiles (acrylamide, ethyl acrylate and styrene). All heterocycles
were isolated (30-50 %) and characterized by FTIR, MS, 1H and 13C NMR, as they were also
evaluated against Gram-positive and Gram-negative bacteria.

Results and Conclusion: All products showed bioactivity against all bacteria, however, the heterocycle
3-(5-nitro-2-furanyl)-5-carboxylamide-4,5-dihydroisoxazole (6b) presented the lowest value
for the minimum inhibition concentration (MIC - 14 µg/mL).
QSAR and Molecular Modeling Studies on a Series of Pyrrolidine Analogs Acting as BACE-1 Inhibitors
Authors: Arya Richa , Gupta Satya Prakash , Paliwal Sarvesh , Kesar Seema , Mishra Achal , Prabhakar Yenamandra Subrahmanya
Published: June 2018

Background:

β-Site amyloidal precursor protein (APP) cleavage enzyme (BACE-1) is
reported as prime cause for progession of Alzheimer’s disease (AD). It is a form of dementia characterized
by degeneration of neurones in brain. Therefore, attempts have been made to find potent
inhibitors of this enzyme.

Methods:

The paper presents an division-based 2D quantitative structure-activity relationship
(QSAR) study on a series of BACE-1 inhibitors to analyse the structural features that may be important
to increase the potency of the compounds.

Results:

The study led to predict some potential leads for the development of potent inhibitors of
BACE-1. One of the molecule with pyrrolidine and pyrrolidinone substitutions exhibited drugreceptor
interactions comparable with reference drug.

Conclusion:

The hydrogen-bond interactions between the molecules and the receptor basically
control the BACE-1 inhibition activity of the compounds.
Maqui (Aristotelia chilensis (Mol.) Stuntz) and murta (Ugni molinae Turcz): Native Chilean sources of polyphenol compounds.
Authors: Rivera-Tovar Pamela R. , Mariotti-Celis María S. , Pérez-Correa José Ricardo
Published: June 2018

In recent years, the production, processing and exportation of maqui and murta Chilean berries
have increased due to their high Total Polyphenols Content (TPC) and high Antioxidant Capacity
(AC). However, the leaves of these berries are agroindustrial discards that present even higher TPC and
AC values. Extracts of leaves and berries of maqui and murta with water, methanol and ethanol as solvents
showed significant bioactivity, like inhibition of alpha-glucosidase (an enzyme involved in the
metabolism of carbohydrates), as well as anti-inflammatory and antidiabetic effects. They are also excellent
sources of polyphenols such as oligomers and polymers of delphinidin, pelargonidin, resveratrol,
among others that have shown health-promoting bioactivity and good bioavailability. Purified extracts
may be useful as supplements for foods and cosmetics, and even as pharmaceutical products. However,
it is necessary to control the variability of their TPC, AC and polyphenols profiles caused by genotype,
environment, processing, storage and stage of harvesting.
Exploration of the Biological Potential of Benzoxazoles: An Overview
Authors: Kale Mayura , Chavan Vijayalaxmi
Published: June 2018

The development of benzoxazole containing drugs and research compounds has been discussed in the present review along with its varied pharmacological activities such as antimicrobial, antiinflammatory, anticancer, antiviral, antiasthmatic, antitubercular, anticonvulsant, lipid modulating, anticoagulants, antidiabetic and anthelmintic activities. The present review is a compilation of the biological activities determined in the research work conducted on benzoxazole-based compounds fused and linked with various other heterocycles.
FDG-PET Scan in Sarcoidosis: Clinical and Imaging Indications
Authors: Maccarone Marica T.
Published: June 2018

Background:

Sarcoidosis is an unknown etiology multisystem inflammatory disease in which noncaseating granulomas (a collections of inflammatory cells) form and grow in various organs, involving predominantly lungs, intrathoracic lymph node, skin and eyes. It most commonly affects patients between 20 and 40 years old of age but it could be observed at any age (female predominance; rare in Asians).  Discussion: The areas of the body usually affected by sarcoidosis are lungs, skin, or lymph nodes; pulmonary and mediastinal involvement is seen in over of 90% of patients. Less commonly eyes, liver, heart, and brain are involved. Any organ, however, can be affected.  Early diagnosis of sarcoidosis can be difficult due to few signs and symptoms in its early stages, and when disease does occur, it may mimic other pathologies, and is made up with chest X-ray, Computed Tomography (CT)-High Resolution CT (HRCT), gallium scans. Fluoro-Deoxy Glucose– Positron Emission Tomography (FDG-PET) is another useful tool to assess the extent of disease and has a potential to evaluate the clinical management of patients responding or not to the treatment.

Conclusion:

In this review, we would summarize in brief the clinical indications of PDG-PET in sarcoidosis and report the imaging features of the main organs involved in this disease.
Sensitive Detection of Human Hemoglobin by MWCNTs-ionic Liquid: Anthraquinone Modified Electrode
Authors: Banaei Aghdas , Shourian Mostafa , Dashtestani Fariba , Eskandari Khadijeh
Published: June 2018

Introduction:

Today, nano-composite gels based on multi-walled carbon nanotubes in room
temperature ionic liquid (MWCNTs-IL-Gel) are an interesting subject.

Materials and Methods:

The nano-composite gels showed convenient electrochemical properties
against redox activities of electroactive biomolecules. Also, the evaluation of hemoglobin
concentration is a critical point in the clinical sample. So, the kind of nano-composite gel which is
composed of NH2 functionalized MWCNTs and [amim] Br IL and anthraquinone 2-carboxilic acid
(AQ) was fabricated and applied in electrochemical detection of hemoglobin. Cyclic voltammograms
of NH2.MWCNTs-IL-AQ modified electrode exhibited redox peak sat -0.5 V (vs. Ag/AgCl) in 0.1 M
phosphate buffer solution ((pH 7.0).

Results:

As the hemoglobin added into the measured solution, the redox current decreased.

Conclusion:

It can be concluded that the increment in the concentration of hemoglobin caused the
decrease in the redox currents in cyclic voltammetry. The NH2.MWCNTs-IL-AQ would detect the
concentration of hemoglobin from 1.64 x10−8 to 4.89x10−7 M.