bluuebunny/crossref_metadata_2025 huggingface dataset:
Congenital Absence of Cervix with Atrial Septal Defect In An Adolescent Girl
Authors:   Nursing Tutor, PhD Scholar in Indian Nursing Council Consortium, College of Nursing, All India Institute of Medical Sciences (AIIMS), GE Road, Tatibandh, Raipur, Chhattisgarh, India., Donel Jissa , Mathew Binu ,   Professor cum Principal, College of Nursing, All India Institute of Medical Sciences (AIIMS) Raipur, Chattisgarh, India., R Bagavathi ,   Nursing Tutor, PhD Scholar in Indian Nursing Council Consortium College of Nursing, All India Institute of Medical Sciences (AIIMS) Raipur, Chattisgarh, India.
Published: March 2024

Background-Cervical agenesis is a rare congenital Mullerian anomaly. Its association with vaginal agenesis is further rare, reported in 39% of cases of cervical agenesis. Case Presentation-Case report of a 15-year-old adolescent girl congenital absence of cervix with atrial septal defect is reported here. Case presented with a history of Primary amenorrhea with cyclical pain in the abdomen for 3-4 months. Investigations were done. The diagnosis was made & was advised for surgical correction. KEYWORDS: agenesis, Mullerian anomaly, Absence of cervix.
The Use of an Audience Response System in a Dental Gross Anatomy Practical Exam
Authors:   University of Detroit Mercy, School of Dentistry, 2700 Martin Luther King Jr. Blvd, Detroit, MI 48208-2576., Ahmad Maha , Hanna Fadia ,   University of Detroit Mercy, School of Dentistry, 2700 Martin Luther King Jr. Blvd, Detroit, MI 48208-2576., Sleiman Naama ,   University of Detroit Mercy, School of Dentistry, 2700 Martin Luther King Jr. Blvd, Detroit, MI 48208-2576., MacDonald Douglas A. ,   University of Detroit Mercy, College of Liberal Arts and Education, 4001 W. McNichols, Detroit, MI 48221-3038.
Published: March 2024

Background: Traditional methods for administering and scoring gross anatomy practical laboratory examinations are time and resource-intensive and can be susceptible to errors in grading. Alternative approaches, such as audience response systems (e.g., clickers) and computerized scoring, appear to hold promise to improve the examination experience for students and improve the efficiency and accuracy of grading. Method: To assess perceptions of using such systems, two cohorts of students who completed the gross anatomy practical examination using clicker technology at the University of Detroit Mercy School of Dentistry were invited to complete the survey. Results: A total of 155 students completed the study. Responses reflect a mostly positive appraisal of the use of clicker technology by most students. In particular, students reported that submitting responses was easier and that the speed of grading and feedback on examination performance improved considerably. Conclusion: Based on the survey results, the use of audience response systems appears to have more benefits than liabilities and seems to be a worthwhile technology to use for practical laboratory examinations. KEYWORDS: Gross Anatomy, Practical Examination, Clickers, Audience Response System.
Performative Beauty – On the Pleasure of Dancing (Argentine Tango)
Authors: Heinrich Falk
Published: March 2024

The video article outlines an aesthetic theory of performative beauty. The article investigates experiences of beauty that occur while one is bodily engaged in an activity. The concrete case is the social dance Argentine tango. The article shows that the flow of interaction between the dancers and the music brings about the dance as an agent proper. The distributed agency allows for a situated, aesthetic awareness that includes the kinaesthetic awareness of the partner’s actions. This transactional awareness crystalizes as the sentiment of beauty.
Hava Durumu Riskinin Yönetiminde İklim Türev Ürünleri: Avrupa Tipi Bir İklim Satım Opsiyonu Tasarımı ve Hedge Etkinliğinin Analizi
Authors: Satıoğlu Bingül , Altay Erdinç
Published: March 2024

Hava durumu riski, tüm ekonomileri ve birçok sektörü etkilemekte olan önemli bir risk türüdür. Hava durumu riskinin bir alt çeşidi olan katastrofik hava risklerinden doğan zararlar, uzun süredir bu sektörde hizmet vermekte olan sigorta ve reasürans şirketleri tarafından yönetilmektedir. Ancak iklim değişikliğine bağlı etkiler tüm ekonomik sektörleri etkileyerek daha belirgin hale geldikçe, katastrofik olmayan hava durumu risklerinin yönetimi de giderek önem kazanmıştır. İklim türev ürünleri, şirketlerin katastrofik olmayan hava durumu riskine maruz kalmaları durumunda karşılaşılan kayıplara karşı bu şirketlerinin kendilerini hedge etmesi için esnek çözümler sunan finansal türev ürünlerdir. İklim türev ürünleri üzerine gerçekleştirilen birçok çalışma bu ürünlerin fiyatlandırılması sorununa değinirken, bu ürünlerin hedge etkinliği üzerine az sayıda çalışma bulunmaktadır. Bu nedenle bu çalışmanın temel amacı, bir iklim türev ürün sözleşmesi tasarlamak ve tasarlanan bu türev sözleşmenin hedge etkinliğini Türkiye tarım sektöründe analiz etmektir. Buna göre çalışmada geçmiş verilerden hareketle mısır verimi (kg/dekar) ve daha çok tarım alanında kullanılan kümülatif büyüyen günler derecesi arasındaki ilişki incelenmiş, ardından buna uygun olarak Avrupa tipi bir satım opsiyonu tasarlanarak Burn Analizi ile fiyatlandırılmış ve son olarak varyans metodu kullanılarak hedge etkinliği analiz edilmiştir. Çalışma sonucunda elde edilen bulgulara göre, iklim türev ürünü kullanılması durumunda mısır yetiştiriciliği yapan çiftçilerin gelir volatiliteleri olarak hesaplanan riskleri %14 ile %34 arasında düşüş göstermekte, mısır verimi ve dayanak varlığın arasındaki korelasyon arttıkça çiftçilerin gelir volatilitelerindeki düşüş artmaktadır.
Possibilities of heat-power spraying of wet charge during formation of structural properties of agglomerated iron ore materials
Authors: Pavlovets V. M.
Published: March 2024

The substantiated problem of improving the structural properties of agglomerated metallurgical raw materials is associated with the formation of a favorable pore structure in iron ore pellets. The author analyzed various methods for the formation of structural properties of molded dispersed materials in various industries. The paper presents the technological capabilities of promising technologies for production of iron ore pellets based on the heat-power spraying of wet charge on pelletizer’s charge skull and pelletized materials. The physical possibilities of heat-power spraying of wet charge in the forced nucleation and in the process of forming the iron ore pellets’ structural properties are disclosed at the stage of pelletizing. The technical features and production operations of the main technologies for wet charge spraying and the design features of devices for obtaining pellets are shown. The paper describes the experimental unit and technology for the forced nucleation. The macro- and microstructure of the germ mass at forced nucleation were studied. Principles of the formation of regulated structure and improved metallurgical properties in iron ore pellets were substantiated. The article presents the description and characteristics of structural changes on the surface of the sprayed charge layer. A hypo­thesis was put forward about the structural correspondence of geometric dimensions and relief of charge lappings and cavities in the sprayed layer with the nature of porosity and germ structure. The germ mass affects the pellets’ structural properties. The author obtained the dependences of structural changes’ relative values on the sprayed layer surface on pressure of air-charge jet and particle size of the sprayed charge. There is relationship between geometric dimensions of the sprayed charge layer and the structural changes’ size. A probable mechanism of porosity formation in the germ mass during heat-power spraying of a wet charge onto the pelletizer skull was formulated. The aerodynamic characteristics of air-charge jet influence the formation of porosity. New possibilities of heat-power spraying of wet charge can intensify pellets production and improve their quality.
Mast Cells: The Key Players in Cardiac Remodelling
Authors:   Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India, Singh Amrit Pal , Buttar Harpal S. ,   Visiting Professor, Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India and Adjunct Professor, Department of Pathology & Laboratory Medicine, Faculty of Medicine, University of Ottawa, Ontario, Canada
Published: March 2024

The Mast Cells (MCs) are part of the immune system and they are actively involved in the inflammatory and allergic reactions. The MCs produce and release a wide variety of biologically active products, eg, histamine, Tumor necrosis factor-α (TNF-α), Transforming growth factor-β (TGF-β), interleukin and renin, which are involved in cardiac remodelling. MCs are considered culprits in various cardiovascular pathologies such as pressure and volume overload, ventricular dilatation, and heart failure. The deleterious role of MCs in failing heart and myocardial remodelling is being rigorously pursued in animal and human studies. The focus of this mini review is to highlight the detrimental effects of MCs in the cardiac remodelling process
Circulating Tumor Cells: Beyond Isolation and Detection
Authors:   Pathologist, Medical and Scientific Affairs, Roche Tissue Diagnostics, Tucson, AZ, USA and Adjunct Professor, Department of Pathology and Laboratory Medicine, University of Missouri, Columbia, MO, USA, McNamara Michelle J.
Published: March 2024

Circulating tumor cells (CTCs) are the precursors to metastases and increased numbers of CTCs in the peripheral circulation have been shown to correlate with decreased progression-free and overall survival. Although the current clinical utility has been focused on the prognostic significance, other clinical applications are being explored, such as determining if a patient is a candidate for treatment, determining the efficacy of treatment, evaluation for resistance to therapy, prediction of metastatic site, or as an early predictor of metastases. Current methodologies are based on quantifying CTCs and include technologies based on physical, immunological, and molecular techniques. However, these have limitations, of which most of them do not have the ability to perform morphological evaluation. Using morphological evaluation, CTCs in body fluids could be used for primary diagnosis in the setting of cancer of unknown primary (CUP) or in initial or early diagnostic scenarios. Additionally, cytological specimens have been shown to be useful for ancillary testing in patients when surgical resection specimens or biopsies are not available. Evaluation of CTCs should incorporate histological, immunehistochemical, and molecular characterization to enable clinicians to obtain the comprehensive diagnostic, prognostic and therapeutic information necessary to provide appropriate personalized care to cancer patients.
The Swan Song of a Pathologist: “Why Do I Love Thee, Pathology? Let Me Count the Ways...."
Authors:   Emeritus Professor of Pathology and Associate Professor of Obstetrics and Gynecology, Emory University, Atlanta, GA, USA, Majmudar Bhagirath
Published: March 2024

Having retired from the active practice of pathology after 50-plus years, I thought I should share my career experience. The word post-mortem slips in habitually, but the word is inept to express the feeling of joie de vivre (joy of living) I uninterruptedly experienced during my wakeful period of more than half a century
İLHAN BERK'İN İLK DÖNEM ŞİİRLERİNDE MODERNLEŞME, BUNALTI VE YABANCILAŞMA İZLEKLERİ
Authors: AŞKAROĞLU Vedi
Published: March 2024

İnsanın yaşamsal sıkıntıları, her dönem edebi üretimin ana ekseninde yer almıştır. Varlığının anlamını keşfetme zorunda olan insan, çevresindeki olay ve koşullardan yola çıkarak kendini tanımaya ve varoluşunu anlamlandırmaya girişir. II. Yeni Şiiri, modernleşmenin karşısında yeni bir anlam arayışına itilen kent insanının trajiğini bireysel bir pencereden sunar. İlhan Berk, ilk dönem şiirlerinde kent içinde ekonomik yaşamın kıskacında kendine ve topluma yabancılaşan ve derin bir bunaltı yaşayan insanın betimlemesini, işçiler, kadınlar, genç kızlar ve çocuklar çerçevesinde işler. Alt ekonomik sınıfa ait insan, onun ilk dönem şiirlerinde, mutsuz, umutsuz, bunaltılı ve yabancılaşmıştır. Bu makalede, İlhan Berk’in ilk dönem şiirlerinde modernleşme ile birlikte deneyimlenen bunaltı, yabancılaşma izleklerinin bireyin penceresinden nasıl algılandığı irdelenecektir.
Quantification of SARS-CoV-2 in wastewater v1
Authors: Ian Walker David
Published: March 2024

This procedure describes the concentration and quantification of SARS-CoV-2 from wastewater as used by the Environmental Monitoring for Health Protection (EMHP) in England programme during the COVID-19 pandemic. It is based on the standard operating procedure developed by a collaboration between Environment Agency National Laboratory Service and Bangor University. This generic protocol was prepared by Cefas to allow laboratories to carry out SARS-CoV-2 quantification from wastewater samples in a way that is similar to the EA’s procedure, while still allowing some variation where necessary. Viral concentration is by ammonium sulphate precipitation followed by centrifugation. Viral RNA extraction is by lysis with guanidine isothiocyanate (GITC) and adsorption to silica. Extracted viral RNA is amplified and detected by quantitative RT-PCR (RT-qPCR). This protocol describes a method for quantification of virus RNA in the test sample and includes production of control materials. The wastewater samples are first clarified by centrifugation. A precipitant (ammonium sulphate) is then added before the sample is incubated for 1 hour at 4°C. This is followed by centrifugation to generate a viral pellet that is suitable for viral nucleic acid extraction. Details of addition of a spike process control (phi6) to the test samples are also described. It is necessary to extract RNA using a method that yields clean RNA preparations to reduce the effect of PCR inhibitors. In this protocol the chaotropic agent GITC is used to disrupt the viral capsid. RNA is then adsorbed to silica to assist purification through several washing stages. Purified viral RNA is released from the silica into a buffer prior to RT-qPCR. The use of the Thermofisher KingFisher Flex Purification System with BioMerieux’s NucliSENS extraction reagents is described here. Other RNA extraction methods that use GITC followed by silica-based purification may also be applicable if they can be demonstrated to give equivalent results. This protocol uses one-step RT-qPCR using hydrolysis probes. In one-step RT-qPCR, reverse transcription and PCR amplification are carried out consecutively in the same tube. Hydrolysis probe-based qPCR utilises a short DNA probe with a fluorescent label and a fluorescence quencher attached at opposite ends. The assay chemistry ensures that as the quantity of amplified product increases, the probe is broken down, and the fluorescent signal from the label increases proportionately. Fluorescence may be measured at each stage throughout the cycle. The first point in the PCR cycle at which amplification can be detected for any reaction is proportional to the quantity of template, therefore analysis of the fluorescence plots enables determination of the quantity of target sequence in the sample.
DERIVA: UMA METODOLOGIA E UMA NARRATIVA POÉTICA
Authors: Laterza Mariana , Barros Jose Marcio
Published: March 2024

Este trabalho tem como objetivo apresentar uma reflexão sensível sobre o uso poético do território urbano a partir do conhecido processo de deriva enquanto método de ressignificação subjetiva dos elementos do espaço urbano, permitindo a criação de narrativas artísticas que possibilitam ao sujeito se apropriar subjetivamente deste local e desta forma construir nele uma noção de “lar”. Para isto, primeiramente introduzimos o conceito de deriva e explicamos sua aplicação metodológica para, logo em seguida, apresentar uma narrativa de percurso, um texto poético resultante de várias derivas pela cidade de Belo Horizonte, em conjunto com imagens que não só descrevem o processo, mas são elas mesmas, parte da narrativa e do processo criativo.
INTERVENÇÕES SENSORIAIS: CHAVE PARA O URBANISMO TÁTICO
Authors: Moura Amanda Pereira Rodrigues , Albuquerque Luana Ferreira de , Diniz Luciana Nemer
Published: March 2024

Este artigo discute a importância das intervenções sensoriais no contexto do urbanismo tático e explora como essas abordagens podem melhorar a experiência urbana contemporânea. O principal objetivo desta investigação é destacar o papel das intervenções sensoriais na transformação das cidades, tornando-as mais interessantes e inclusivas para os seus habitantes, além de promover a conexão entre as pessoas e o ambiente construído. A metodologia adotada se amparou em pesquisa bibliográfica e material previamente publicado (livros e artigos), destacando autores que abordam questões relevantes para a pesquisa, como Harvey, Brenner e Pallasmaa. Os resultados provenientes do estudo apresentam exemplos importantes que podem ser aplicados em diversos contextos urbanos. Conclui-se que o urbanismo tático combinado com uma abordagem sensorial oferece um caminho promissor para a renovação da cidade contemporânea, promovendo um ambiente urbano mais coeso e enriquecedor para todos os cidadãos.
VIOLÊNCIA E COMUNICAÇÃO ON-LINE: ANÁLISE DO CONTEÚDO DE PUBLICAÇÕES VIOLENTAS NO FACEBOOK
Authors: Datrino Mariana Alarcon , Volpato Alana Nogueira
Published: March 2024

Nos últimos anos é possível observar o crescimento de uma onda conservadora no Brasil, com a qual ascenderam diversos movimentos sociais regressivos amparados por redes digitais. Este estudo pretende compreender de que forma diferentes violências são manifestadas nas publicações do Movimento Conservador em sua página do Facebook. Espera-se identificar aspectosligados às diferentes formas de violência nas publicações, demonstrar as articulações entre asformas de violência e apresentar como os seguidores se engajam com esse conteúdo. Para tanto, coletamos publicações da página durante um mês e meio. Após filtragem dos dados, foram analisadas e classificadas 55 publicações que apresentavam conteúdo violento. Concluímos que a percepção do outro como inimigo, configura uma violência simbólica na comunicação digital de movimentos sociais conservadores e oferece sustentação para outras violências que extrapolam o ambiente virtual e contribuem para a construção de uma cultura violenta.
O APARECIMENTO POLÍTICO DE MULHERES NEGRAS EM IMAGENS CINEMATOGRÁFICAS
Authors: Gonçalves Beatriz Drosdrocky , Salgueiro Marques Ângela Cristina
Published: March 2024

O presente trabalho visa analisar como imagens de mulheres negras retratadas em produções cinematográficas podem promover rupturas em enquadramentos desvalorizantes, apresentando outras legibilidades e figurações possíveis. A relação dessas imagens com as narrativas escolhidas revela resistências às perspectivas historiográficas que não são capazes de fugir a estereótipos raciais. Escolhemos os filmes Kbela (2015), da cineasta Yasmin Thayná, e Cores e Botas (2010), escrito e dirigido por Juliana Vicente, para refletiracerca de como essas produções tematizam a influência que o racismo possui na vida de mulheres negras e como elas buscam sua autodefinição, a valorização de seus conhecimentos, o enfrentamento de violências e injustiças através da experiência de seus corpos. O entrelaçamento entre estética e política presente nesses filmes relaciona-se à capacidade que suas imagens possuem de transformar as condições de reconhecimento da dignidade dos sujeitos filmados.
A SOCIOEDUCAÇÃO NO INSTAGRAM: MAPEAMENTO DO ATENDIMENTO SOCIOEDUCATIVO BRASILEIRO
Authors: Swaze Anchieta Silva Priscilla , De Castro Sena Patrícia Rakel
Published: March 2024

O artigo apresenta um mapeamento sobre as instituições brasileiras que executam a política pública da Socioeducação no Instagram, para refletir sobre o processo de polarização e invisibilidade desta temática. Essa proposta de estudo se apresenta pelo histórico de preconceitos e distanciamento com a Socioeducação pela sociedade. Para isso, buscou-se apoio nos conceitos de Socioeducação, Mídia Social Digital, Comunicação Pública, Polarização e Invisibilidade para construir esse debate; uma pesquisa de campo em dados públicos virtuais e abertos para mapeamento das instituições que possuem perfis no Instagram, e a análise dos conteúdos na perspectiva da pesquisa quantitativa e qualitativa.
MEMÓRIA SUBTERRÂNEA: A SOBREVIVÊNCIA DE UMA OBRA DE ARTE
Authors: Miranda Cybelle Salvador
Published: March 2024

Uma obra de arte emerge no meio do Arquivo como peça-chave para retirar do esquecimento uma teia de relações pessoais e sociais entre sujeitos da sociedade belemense da segunda metade do século passado. O tema — Cristo de duas faces — é a imagem que serve de pretexto para a compreensão das lacunas existentes no homem contemporâneo, do vazio existencial gerado pela perda do sagrado, que, não por acaso, sobrevive na contemporaneidade como elo a reatar a memória como habitada e plena de sentido. O artigo adota a perspectiva qualitativa, imbricando autoetnografia, memória e psicologia ao seguir as trilhas de vidas e obras revisitadas pela vivência do arquivo.
“VIRTUALMENTE, DÁ PRA SE CANSAR?”: DINÂMICAS PSICOPOLÍTICAS NA ENTREVISTA COM LU, DO MAGALU
Authors: Oliveira Raquel Assunção , Bezerra Josenildo Soares
Published: March 2024

Este estudo analisa uma entrevista da influenciadora virtual Lu – personagem porta-voz das peças e estratégias comunicacionais da marca Magazine Luiza – à jornalista Marília Gabriela. O bate-papo, fruto de uma ação publicitária da marca, estreou no YouTube no dia 14 de dezembro de 2022. A partir das contribuições de Deleuze (2013), Crary (2016) e Han (2017; 2018), entre outros(as) autores(as), esta pesquisa busca compreender questões reiteradas pela jornalista: tempo e cansaço na cultura contemporânea. Nesse sentido, merece atenção a variedade de tópicos abordados – que oscilaram desde questões relativas a gênero, estética do corpo e fake news até posicionamento das marcas e outras atualidades do mundo virtual, como são as danças do TikTok e os memes da internet. Essas dimensões discursivas têm sua base de investigação a partir das teorizações foucaultianas e, ao final, apresentamos a personalidade multitasking da influenciadora virtual como metonímia para os sujeitos psicopolíticos que emergem da atual sociedade de controle.
Melanocytic nevus: Clinical features and colorimetrial evaluation
Authors: Sakharova Mariia V. , Klyuchareva Svetlana V. , Kashutin Sergey L. , Levit Mikhail L. , Shapchits Natalya L.
Published: March 2024

BACKGROUND: An increase in the frequency of registration of skin malformations, benign, precancerous and malignant skin neoplasms requires new approaches to their diagnosis and treatment. The different depth of melanocytic nevi in the epidermis and dermis is reflected in the color of the melanocytic nevus.
AIM: to study the localization, size and intensity of pigmentation of melanocytic nevi depending on their color.
MATERIALS AND METHODS: A clinical and instrumental study of 280 people with melanocytic nevi of various localization was conducted using their colorimetric assessment and dermatoscopic diagnosis. If melanoma was suspected, patients were consulted by an oncologist. The diagnosis of "melanoma" was confirmed histologically.
RESULTS: Melanocytic nevi are more localized on the face than on the abdomen, back or chest, which is confirmed statistically. The largest sizes ― 5.5 mm ― are reached by nevi having a dark brown color, and, consequently, localized in the epidermis above the basal layer, and the smallest ― 2.0 mm ― melanocytic nevi with brown color located in the basal layer of the epidermis, which is also statistically confirmed.
CONCLUSION: The largest sizes ― 5.5 mm ― are reached by nevi having a dark brown color, and, consequently, localized in the epidermis above the basal layer, and the smallest ― 2.0 mm ― melanocytic nevi with brown color located in the basal layer of the epidermis.
Differentiated approach to external acne therapy
Authors: Olisova Olga Yu.
Published: March 2024

Acne is a serious medical and social problem due to the widespread prevalence of the disease. Localized mainly on the face, acne leads to the development of disorders in the psycho-emotional sphere, significantly reducing the quality of life.
The aim of the study was to study the effectiveness and safety of Epiduo/Effezel gel (adapalene 0.1% and benzoyl peroxide 2.5%) in patients with papulopustular acne.
The Clinic of Skin and Sexually Transmitted Diseases of the Clinical Hospital No. 2 of Sechenov University has accumulated extensive experience in the treatment of acne. In the diagnostic and treatment department, patients with mild to moderate acne receive consultations and treatment almost every day. A dermatological examination is carried out visually with a simple count of eruptive elements: papules, pustules and nodes, on the basis of which the degree of severity is determined. Patients with severe forms of acne receive systemic retinoids with corrective therapy until a certain cumulative dose is reached, and then patients receive topical maintenance therapy intermittently for 12 months.
Despite the development of effective methods for treating this dermatosis, patient adherence to treatment remains low. This is due, first of all, to the duration of therapy, not always the rapid achievement of the expected result, and to the development of psycho-emotional disorders in patients. In the latest edition of the Russian Society of Dermatovenerologists and Cosmetologists clinical guidelines for the treatment of mild to moderate acne with a high level of evidence A1, it is recommended to use benzoyl peroxide and a fixed combination of adapalene and benzene peroxide. When prescribing benzene peroxide (Baziron AS), we observed the best results in clearing the skin of rashes in the presence of a few papulopustular elements in the clinical picture due to the triple action of benzoyl peroxide ― antimicrobial, keratolytic and sebostatic. In our experience, it usually took 4 to 6 weeks to achieve clinical remission, and we did not note a single case of the development of bacterial resistance during treatment. For moderately widespread papulopustular acne rashes of moderate severity, as well as in cases of severe forms of the disease, when it is impossible to prescribe systemic isotretinoin or there is a tendency to scarring of the primary elements, we used a fixed combination of adapalene 0.1% and benzoyl peroxide 2.5% (Effezel) with anti-inflammatory, antimicrobial, keratolytic, sebostatic, comedolytic and anticomedogenic effects.
In the arsenal of dermatologists and cosmetologists there are drugs for the external treatment of mild to moderate papulopustular acne with a high level of evidence. Thus, for papulopustular acne with a few inflammatory (papules and pustules) rashes, benzoyl peroxide gel may be recommended. For moderately widespread papulopustular acne with the presence of comedones (moderate severity), a fixed combination of adapalene and benzoyl peroxide can be recommended as the first line of therapy.
An Innovative Communication Paradigm for the Future of Public Relations: Artificial Intelligence
Authors: ÇERÇİ Ümmü Özlem
Published: March 2024

This article examines the role of artificial intelligence, an innovative communication paradigm for the future of public relations. Artificial intelligence stands out as a factor that leads to significant changes and transformations in the communications industry. This article extensively examines how artificial intelligence, utilized to optimize information processing, data analysis, and decision-making processes, can have a transformative impact within the field of public relations. The article focuses on how artificial intelligence changes and improves public relations practices in areas such as media monitoring, crisis management, reputation management, customer relationship management and content production. It also focuses on the potential of AI to help develop better targeting and communication strategies, with particular emphasis on its data analysis and predictive capabilities. This article provides a comprehensive evaluation that will help public relations professionals, businesses and communications industry stakeholders understand the potential of artificial intelligence technology. It also addresses future communications trends and current and potential questions regarding the ethical dimension of artificial intelligence, offering guidance on how public relations can be integrated with this innovative technology.
CONSIDERATIONS FOR THE PARAMETERISATION OF A CHATTER DETECTION ALGORITHM
Authors:   Laboratory for Machine Tools and Production Engineering, WZL of the RWTH Aachen University, BRECHER CHRISTIAN , WEILER PAUL ,   Laboratory for Machine Tools and Production Engineering, WZL of the RWTH Aachen University, KLIMASCHKA RALPH ,   Laboratory for Machine Tools and Production Engineering, WZL of the RWTH Aachen University, NEUS STEPHAN ,   Laboratory for Machine Tools and Production Engineering, WZL of the RWTH Aachen University
Published: March 2024

Process instabilites due to the regenerative effect limit the material removal rate of cutting machine tools. A method developed at the Laboratory for Machine Tools and Production Engineering (WZL) at RWTH Aachen University reduces the experimental effort of determining stability limits for milling. The method bears on a time-domain chatter detection algorithm, which detects process instability based on predefined threshold values. Up to now, the definition of the threshold values has been derived from a selective number of sample tests. To investigate the transferability of the chatter detection algorithm to various boundary conditions cutting tests are carried out. In addition, a new stability criterion for high frequency chatter oscillations is introduced. The results are analysed with regard to factors that require an adjustment of the threshold values. Based on the results, a parameterisation of the chatter detection algorithm is presented.
CALCULATION OF THE PROBABILITY OF TEST OBJECT COMPLIANCE WITH THE SPECIFIED REQUIREMENTS AND NON-BINARY DECISION-MAKING RULES
Authors:   Technical University of Kosice, RIMAR MIROSLAV , FEDAK MARCEL ,   Technical University of Kosice, KULIKOV ANDRII ,   Technical University of Kosice, BILONOZHKO M.V. ,   Dnipropetrovsk Regional State Scientific and Technical Center of Standardization, Metrology and Certification, RUDKO K.V. ,   Dnipropetrovsk Regional State Scientific and Technical Center of Standardization, Metrology and Certification, MARTYNOVA V.V. ,   Dnipropetrovsk Regional State Scientific and Technical Center of Standardization, Metrology and Certification, YEROMIN O.O. ,   Department of Ecology, Heat Engineering and Occupational Safety, Ukrainian State University of Science and Technology, SAVVIN O.V. ,   Department of Ecology, Heat Engineering and Occupational Safety, Ukrainian State University of Science and Technology, SUKHA I.V. ,   Ukrainian State Chemical and Technological University of Dnipro, KRENICKY TIBOR ,   Technical University of Kosice
Published: March 2024

The probability of test object compliance with the specified requirements and non-binary decision is a measure of how likely the test object is to meet the criteria for acceptance or rejection based on multiple factors. It is necessary to calculate by using a valid mathematical model that takes into account the test object's characteristics, the test conditions, the test criteria, and the uncertainty of the measurements. The significance of the probability of test object compliance with the specified requirements and non-binary decision can help to evaluate the quality, reliability, and performance of the test object, as well as to support decision making in complex situations.
ADVANCED COMBUSTION CHAMBER FOR HCCI TECHNOLOGY APPLICATION
Authors:   Technical University of Kosice, Faculty of Mechanical Engineering, TARBAJOVSKY PAVOL , PUSKAR MICHAL ,   Technical University of Kosice, Faculty of Mechanical Engineering, FILO MILAN ,   ECO-Invest, Namestie SNP
Published: March 2024

Engines using HCCI technology are potentially significantly more efficient compared to classic spark-ignition engines. Improved thermal efficiency is the result of several factors such as elimination of gas throttling losses, shorter burning time, higher compression ratios and lower heat transfer losses. The upper limit of the compression ratio is the occurrence of detonations. As part of the development of lean combustion, there are several technologies that are being developed to achieve long-term reliability. The solution is to create fuel-rich zones inside the chamber, e.g., using fuel stratification. Therefore, a "Combustion chamber with the implementation of homogenization and controlled self-ignition of the fuel mixture using compression" was designed, for which a patent was granted. The design was based on the assumption that a stratified charge engine creates a richer fuel mixture near the spark and a leaner mixture throughout the rest of the combustion chamber. The patent system was subjected to a simulation analysis, which confirmed a significant yield for emission reduction.
DEVELOPMENT OF A MATHEMATICAL MODEL FOR THE ENERGY BALANCE OF THE LASER CLADDING PROCESS OF METALLIC POWDERS WITH A COAXIAL NOZZLE
Authors:   Industrial and Business Technologies, Ukrainian State University of Science and Technologies, KARAKASH YEVHEN , RIMAR MIROSLAV ,   Technical University of Kosice, Faculty of Manufacturing Technologies with a seat in Presov, KARPOVYCH OLENA ,   Oles Honchar Dnipro National University, Physical and technical faculty, ZHUMAR DENYS ,   Oles Honchar Dnipro National University, Physical and technical faculty, KIZEK JAN ,   Technical University of Kosice, Faculty of Manufacturing Technologies with a seat in Presov, FEDAK MARCEL ,   Technical University of Kosice, Faculty of Manufacturing Technologies with a seat in Presov, KULIKOV ANDRII ,   Technical University of Kosice, Faculty of Manufacturing Technologies with a seat in Presov
Published: March 2024

Modern technologies require innovative solutions for producing complex structures from various materials. Additive manufacturing (AM) or 3D printing presents such a challenge and has significantly impacted the environment across manufacturing sectors, regardless of size. Researchers and technicians have developed new design approaches by exploring fundamental components, materials, and manufacturing processes beyond traditional frameworks, addressing global complex material and design challenges. Laser cladding of metal powders with a coaxial nozzle is one such technology, offering highly productive processes for large-scale component production. Fiber lasers are optimal for providing laser radiation, ensuring required emission quality and stability. The authors seek to develop a mathematical model for the energy balance of coaxial laser cladding of metal powders, aiming to provide an overview of energy consumption levels and unit characteristics for powder delivery, inert gas, and laser radiation sources in direct metal powder coating setups.
Postmortem Toksikolojik Analizlerde Saptanan Eroin Metabolit ve Yan Ürünlerinin İncelenmesi
Authors: İzci Abdülkadir , Dağlıoğlu Nebile , Dereli Ayşe Kurtuluş , Acar Kemalettin
Published: March 2024

Objective: The aim of this study is to discuss the diversity, frequency and characteristics of heroin metabolites and alkaloids in postmortem toxicological analyses in the light of the literature.
Methods: This study was conducted by retrospectively examining the toxicological examination results after autopsies between January 2020 and April 2022. The cases; were evaluated in terms of sex, age, origin, drug-stimulant substances detected and their diversity.
Results: Drugs or stimulants were found in the toxicological examinations of 45 (4.8%) of 919 deceased examination and autopsy cases. Fourty one of these cases were male and 4 were female. Methamphetamine and amphetamine-like substances were most commonly found in 26 cases. Opiate derivatives were found in 16 cases, 6-monoacetylmorphine (6-MAM) in 11 cases, meconine in 10 cases and noscapine in 7 cases. Morphine and codeine were detected and the morphine/codeine ratio was greater than 1 in all 8 cases for which quantitative analysis was performed. In addition to these substances, n-ethylamphetamine, norpseudoephedrine, thebaine, acetylcodeine, 2-ethylidene-1,5-dimethyl 3,3-diphenylpyrrolidine, methadone, methyldiethanolamine, 3,4-methylenedioxyamphetamine, papaverine, ephedrine/pseudoephedrine and codeine were detected.
Conclusion: Detection of alkaloids and metabolites such as acetylcodeine, noscapine, meconin, papaverine and thebaine suggests illicit heroin use. In addition, papaverine, noscapine and their metabolites are found in higher amounts in the composition of heroin produced in Southwest Asia than in Southeast Asia. These detected alkaloids and metabolites may be useful in detecting illegal heroin use and determining the origin of heroin.
Yasa Dışı Madde Kullananlarda Denetimli Serbestlik Tedbiri Uygulamasının Uygulayıcı Uzmanlar ve Hakkında Tedbir Uygulananlarca Değerlendirilmesi
Authors: Uzunyayla Zuhal , Alkan Nevzat
Published: March 2024

Amaç: Bu çalışmada 2005 yılında yürürlüğe giren Türk Ceza Kanunu ile madde kullanıcıları için alternatif bir ceza infaz sistemi olan Denetimli Serbestlik Tedbiri uygulamasının etkinliğinin değerlendirilmesi, işleyişindeki aksaklıkların tespit edilmesi ve sistemin geliştirilmesine yönelik çözüm önerileri sunulması amaçlanmıştır.
Yöntem: Çalışma İstanbul’da bulunan dört adet Denetimli Serbestlik Şube Müdürlülüğü’nde Ekim 2014-Haziran 2015 tarihleri arasında yürütülmüş olup çalışmada madde kullanımı nedeniyle Türk Ceza Kanunu’nun 191. maddesi kapsamında “Tedavi ve Denetimli Serbestlik Tedbiri”ne hükmolunan 382 kişiye (grup 1) ve müdürlüklerde çalışan 100 denetimli serbestlik uzmanına (grup 2) sosyodemografik verileri ve sisteme dair görüşlerini içeren anket uygulanmıştır.
Bulgular: Grup 1 örnekleminin; büyük oranda bekar, erkek, genç erişkin, ortaokul ve altı düzeyde öğrenim görmüş, gelir getirici bir işte çalışanlardan oluştuğu, en yaygın kullanılan maddenin esrar olduğu, grup 2 örnekleminin; 4 ayrı meslek grubundan oluştuğu, büyük çoğunluğunun sosyolog olduğu, farklı meslek gruplarının aynı görev tanımıyla aynı işi yaptıkları, madde kullanıcılarıyla çalışma konusunda deneyimlerinin az olduğu saptanmıştır.
Sonuç: Her iki grupta da sistemin genel olarak farkındalık sağlama özelliğinin yeterli görülmediği, rehabilitasyon faaliyetlerinin sınırlı olduğu saptanmıştır. Doğrudan denetimli serbestlik olgularında sistemin etkinliğini ölçmeye yönelik araçlar geliştirilmesi, sistemin düzenli aralıklarla objektif olarak değerlendirilmesi, rehabilitasyon faaliyetlerinin artırılması, sivil toplum kuruluşları, akademiler ve toplumsal katılımın sağlandığı bir yapılanma oluşturulmasının denetimli serbestlik sistemine olumlu katkılar sağlayacağı sonucuna varılmıştır.
Perinatal outcomes of preterm births occuring to native-born and migrant mothers in Iceland
Authors:   Department of Obstetrics and Gynecology, Landspítali – The National University Hospital of Iceland, Gunnarsdóttir Ásdís Björk , Thorkelsson Thordur ,   Children's Hospital , Landspítali – The National University Hospital of Iceland, Bjarnadóttir Ragnheidur I ,   Department of Obstetrics and Gynecology, Landspítali – The National University Hospital of Iceland, Faculty of Medicine, University of Iceland, Gudmundsdottir Embla Yr ,   The Reykjavík Birth Center, Faculty of Nursing and Midwifery, University of Iceland
Published: March 2024

INTRODUCTION: The aim of this study was to assess the incidence and perinatal outcomes of preterm births in Iceland during 1997-2018 and compare outcomes of Icelandic and migrant mothers. METHODS: The population in this historical population-based cohort study was all preterm (<37 weeks gestation) live-born singletons born in Iceland from January 1, 1997 to December 31, 2018 and their mothers; a total of 3837 births. Data was obtained from the Icelandic Medical Birth Registry. The group of migrant women was defined as women with other citizenship than Icelandic. Migrant women were divided into three groups based on their country of citizenship Human Development Index (HDI). Both descriptive and analytical statistics were used in data processing. RESULTS: The incidence of preterm births in Iceland increased during the study period (3,9% 1998-2001 vs. 4,5% 2012-2018, p<0,005) and was significantly higher among migrant mothers, especially from countries with the lowest HDI (OR 1,49 (CI 1,21-1,81) p<0,001) . Infants of mothers from countries with the lowest HDI had a significantly lower prevalence of respiratory distress syndrome compared with infants of Icelandic mothers (4,5% vs. 11,4%, p=0,035) meanwhile infants of mothers from countries with a medium high HDI were more often small for gestational age compared with infants of Icelandic mothers (11,4% vs. 6,9%, p=0,021). CONCLUSION: Preterm births have become more common in Iceland and the incidence is significantly higher among migrant mothers, however the outcomes of preterm infants are generally good and mostly comparable between Icelandic and migrant mothers.
Gastroschisis and omphalocele: Incidence and outcome
Authors:   Faculty of medicine, University of Iceland, Child and Adolescent Psychiatric Department, Landspitali - National University Hospital of Iceland, Reynisdottir Kristin Fjola , Hjartardottir Hulda ,   Faculty of medicine, University of Iceland, Obstetrics and Fetal Medicine, Landspitali – National University Hospital of Iceland, Rosmundsson Thrainn ,   Faculty of medicine, University of Iceland, Pediatric Surgery, Landspitali University Hospital, Thorkelsson Thordur ,   Faculty of medicine, University of Iceland, Neonatal Intensive Care at Children's Hospital, Landspitali – National University Hospital of Iceland
Published: March 2024

INTRODUCTION: Gastroschisis and omphalocele are the most common congenital abdominal wall defects. The main purpose of this study was to investigate the incidence, other associated anomalies and the course of these diseases in Iceland. MATERIAL AND METHODS: The study was retrospective. The population was all newborns who were admitted to the NICU of Children's Hospital Iceland due to gastroschisis or omphalocele in 1991-2020. Furthermore, all fetuses diagnosed prenatally or post mortem where the pregnancy ended in spontaneous or induced abortion, were included. RESULTS: During the study period, 54 infants were born with gastroschisis and five with omphalocele. The incidence of gastroschisis was 4.11 and omphalocele 0,38/10,000 births. There was no significant change in the incidence of the diseases during the study period. In addition, five fetuses were diagnosed with gastroschisis and 31 with omphalocele where the pregnancy was terminated. In addition to gastroschisis in the live born infants and fetuses the most common associated anomalies were in the gastrointestinal or urinary tract but in infants and fetuses with omphalocele anomalies of the cardiac, central nervous or skeletal systems were the most common. Sixteen fetuses diagnosed with omphalocele had trisomy 18. Mothers aged 16-20 were more likely to give birth to an infant with gastroschisis than older mothers (p<0.001). Primary closure was successful in 86% of the infants. Those reached full feedings significantly earlier and were discharged earlier. Overall survival rate was 95%. Three children were still receiving parenteral nutrition at discharge due to short bowel syndrome. CONCLUSIONS: The incidence of gastroschisis in Iceland is in accordance with studies in other countries but but the incidence of omphalocele is lower, which can be partly explained by spontaneous or induced abortions. Other anomalies associated with omphalocele are more severe than those associated with gastroschisis. Primary closure was associated with more benign course. Children with gastroschisis may need prolonged parenteral nutrition due to shortening of their intestines.
Integration of Mobile Augmented Reality Applications for Engineering Mechanics Learning with Interacting 3D Objects in Engineering Education
Authors:   Faculty of Engineering, Universitas Negeri Padang, Indonesia, Waskito
Published: March 2024

The development of Augmented Reality (AR) technology has proliferated in the educational arena. The results of subjective observations of engineering mechanics learning show the decline in student interest and understanding caused by conventional teaching methods, which are the biggest obstacles in the learning process, thus impacting students’ cognitive abilities. This study develops AR as an instructional media for engineering mechanics using the Analyse, State, Select, Utilise, Require, and Evaluate (ASSURE) instructional design model with an R&D approach. This study used performance assessment instruments, questionnaires, and interviews with students and lecturers as the primary data. The subjects of this study were 103 students of Mechanical Engineering Vocational Education at Universitas Negeri Padang in the 2020–2021 academic year. The results showed that the use of AR-based learning media had a positive impact on students’ understanding of basic concepts and skills. In addition, AR media support independent learning and provide direct feedback to students. The acquisition of validation results from material experts is 88.48% (very valid), media experts of 89.26% (very valid), and linguists of 87.41% (very valid). The average practicality test results from the lecturer’s responses were 89.70% (very practical) and 81.63% (practical) student responses. In conclusion, the results of developing mobile AR applications that are declared valid and practical can provide a more interactive and exciting learning experience for students to increase their interest and understanding of learning. Therefore, mobile AR is an exciting option for further integrating engineering education into higher education.
Educational Video Recommender System
Authors:   Faculty of Sciences Dhar El Mehraz, Sidi Mohamed Ben Abdellah University, Morocco, Timmi Mohamed
Published: March 2024

In recent years, informal education has witnessed a significant upsurge, fueled by technological advancements and the ubiquitous availability of online educational content. Internet users, including students, researchers, and teachers, are increasingly seeking supplementary educational resources across diverse online repositories to augment their knowledge. Within this landscape, recommendation systems emerge as indispensable tools, aiding users in the discovery of pertinent resources aligned with their academic interests. This article proposes a novel recommendation methodology leveraging a hybrid approach, incorporating both Content-Based Filtering (CBF) and Collaborative Filtering (CF) algorithms. By harnessing information from a myriad of data repositories, this system excels in identifying and presenting the most relevant and desirable educational resources, with a particular focus on meeting the needs of students. This holistic approach embraces user profiles, contextual information, and supplementary data, underscoring its potential to revolutionize informal education in the digital age.
Training of Chinese Language Teachers at Confucius Institutes in the UK: A Case Study of the University College London Institute of Education Confucius Institute
Authors: Zhang Xinyue
Published: March 2024

The proficiency of Chinese language teachers is a crucial factor in determining the effectiveness and quality of Chinese language teaching. Over the years, the Confucius Institute in the UK has experienced significant growth, leading to the gradual expansion of the Chinese language teaching industry. Consequently, there has been a surge in interest in local Chinese language teacher training. This article focuses on the Confucius Institute at the University College London Institute of Education and examines its Chinese language teacher training mode from diverse perspectives. It also provides specific recommendations based on a thorough analysis, aimed at offering guidance and inspiration for the training of Chinese language teachers not only in the UK but worldwide.