bluuebunny/crossref_metadata_2025 huggingface dataset:
Retrospective analysis of oral cancers in Shimla-Himachal Pradesh (2011-2018): a hospital-based study
Authors: Fotedar Shailee , Fotedar Vikas , Gupta Manish , Bhardwaj Vinay , Thakur Purnima , Thakur Shabnan
Published: July 2021

Background: Oral cancer ranks in the top three of all cancers in India, and oral cancer control is quickly becoming a global health priority. To analyse the epidemiological and clinical profile of oral cancer patients treated in Tertiary Care Center, IGMC, Shimla from 2011-2018.Methods: A retrospective study of patients with oral cancers treated from 2011-2018 at TCC, IGMC, Shimla was conducted. Demographic characteristics, tobacco use and oral cancer characteristics related to site, histology and stage at presentation were recorded from patient file records at TCC, Shimla. Data was analysed by Statistical package for social sciences (SPSS) version 16. Statistical test used was chi square test. A p value of 0.05 was considered to be statistically significant.Results: Oral cancer represents 1.53% of overall cancers. The total number of subjects were 246 out of which 205 were men and 41 were women thus making a male female ratio of 5:1. Peak age of occurrence is the 5th and 6th decade. The most common site involved was tongue (37.5%) followed by buccal mucosa (35.5%). Buccal mucosa was significantly associated with male gender, age group of less than 40 years. Lip was significantly associated with female gender, more than 60 years and with no habits. Floor of the mouth was significantly associated with males, 40-60 year age group and tobacco smoking.Conclusions: Strategies to overcome the present situation must be undertaken at state level by oral health programs for the early diagnosis and prevention and to support a tobacco free environment.
Knowledge on prevention of breast cancer among females attending outpatient department of All India Institute of Medical Sciences, Jodhpur, Rajasthan
Authors: Nebhnani Mamta Rajput , Phalswal Uma , Ohri Uma , Raj Shalini , . Vineeta , . Suman , Singh Shivangi
Published: July 2021

Background: Breast cancer is the most common cancer and principal cause of death among females. Breast cancer related awareness and practices of female are known to have crucial contribution in the prevention. The aim of the study was to assess knowledge on prevention of breast cancer among females.Methods: This descriptive study was conducted on females attending outpatient departments of All India Institute of Medical Sciences, Jodhpur, Rajasthan. 70 females within age group of 15-60 year were enrolled in the study via convenience sampling technique. Data was collected through face-to-face interview. Reliability of self-structured knowledge questionnaire was determined by KR 20 method and found reliable (0.84). Data collected was analyzed for frequency, mean, standard deviation and test.Results: Findings showed that most (51%) of the respondents were from age group 15-30 years. Only 14% of the subjects had family history of breast cancer. Most of the subject (81.4%) previously heard about breast cancer. The mean knowledge score was 14.43±2.9. Most of the respondents (74.3%) had average knowledge about prevention of breast cancer whereas only 3% had excellent knowledge levels. Knowledge of subjects about prevention of breast cancer was found to have significant association with level of education and area of living only.Conclusions: Result of the study provided information that maximum number of participants had average knowledge about different aspects about prevention of breast cancer. The knowledge of females was significantly associated with their educational status.
A cross-sectional study on utilization of maternal health services and its determinants among rural population of district Sitapur, Uttar Pradesh
Authors: Neyaz Arslan , Chaubey Jaideep K. , Ahmed Malik S. , Kumar Virendra , Nayak Kripashankar
Published: July 2021

Background: In India, despite substantial improvements in maternal health over the last decade or so, still condition is even poor in rural areas. As per National health policy 2017, target is to reduce MMR to 100 by 2020 and sustaining antenatal coverage at 100%, institutional delivery 80% and skilled attendance of birth 100% by 2025.The study is conducted with the objective to assess the pattern of maternal health service utilization and to identify the factors affecting it.Methods: A community based cross-sectional study was conducted at field practice area of Rural Health Training Centre, Hind Institute Of Medical Sciences, Sitapur with a sample of 208 women selected using systematic random sampling. SPSS Statistics 20.0 was used for data entry and calculation of statistical tests.Results: ANC utilization was found to be 70.7% whereas minimum recommended ANC visits were 50%. Only 54.8% deliveries were found to be institutional whereas 59.1% women received at least one postnatal check-up in our study. Most common reason for not utilizing ANC, Institutional delivery and PNC services was found to be tradition, availability of trained person and no need respectively. A highly significant association was found between maternal health service utilization and woman’s education, partner’s education, partner’s occupation, birth order and standard of living index (p<0.05).Conclusions: This study established that educating the population, empowering women, promoting maternal health service utilization in multipara’s and improving the socio-economic status of the family would yield greater results in increasing the use of maternal health services.
Osteoporosis: A silent disease fraught with fragility fractures in geriatric population
Authors: Vashisht Arun
Published: July 2021

As per the Population Census2011, the elderly (aged 60 years or above) population in India was about 104 million (53 million females and 51 million males). As per United Nation Population Fund and Help Age India report speculated this number to rise to 173 million by 2026. The purpose of this article is to review the available literature regarding the different ways at hand for osteoporosis evaluation and diagnosis, various therapeutic modalities available for treatment and how they can be utilized for prevention of fractures due to insufficiency of bones in consequence of osteoporosis.

The recommendations and conclusions have been evolved after the thorough review of various literatures on osteoporosis. The evidence based recommendations are based on systemic reviews, meta-analysis and randomized controlled trials (RCTs), wherever available.

The evidences and recommendations extracted after extensive review of literature has been provided for diagnosis, assessment of risks for fractures, pharmacological therapies with life style modifications, treatment duration of bisphosphonate therapy.

The evidences and recommendations extracted after extensive review of literature helped in formulating guidelines to provide a concised but complete overview of all aspects of osteoporosis that will definitely help all healthcare professionals.
Nuevos datos biográficos sobre el compositor Antonio Ugena, maestro de la Real Capilla de Madrid (1745-1817)
Authors: Fuente Charfolé José Luis de la
Published: July 2021

Una buena parte de las biografías de maestros de capilla hispánicos se encuentran en constante estado de revisión y perfeccionamiento. La localización del acta bautismal del maestro de la Real Capilla madrileña, Antonio Ugena, viene a corregir los datos conocidos derivados de una lectura errónea de fuentes.
Paul Dukas: Legacies of a French Musician
Authors: Ducatteau Héloïse Elisabeth Marie-Vincent Ghislaine
Published: July 2021

Libro que propone considerar Paul Dukas tanto musicologista como profesor y compositor. Fuentes principales son libros ya dedicados al maestro, cartas de sus alumnos y archivos de prensa.
Analisis Elastisitas Pendapatan Rumah Tangga di Indonesia
Authors: Hafizah Dian , Hakim Dedi Budiman , Harianto Harianto , Nurmalina Rita
Published: July 2021

Demand for food products is inevitable, this condition is related to food products as a staple food for the sustainability of human life. In Indonesia, the demand for food depends very much on the needs of the people. The purpose of this study is to analyze food demand in Indonesia which is divided into 4 categories of regions: rich cities, poor cities, rich villages, and poor villages need through research that can be obtained about getting assistance in accordance with the consumption demand of people in Indonesia. The research method used secondary data with panel data types obtained from SUSENAS data. The analytical method used to estimate the demand system was through econometrics demand, namely the QUAIDS model and then the data were processed using the SAS program. The results showed a comparison of the total number of households allocated specifically for food if sorted out, namely poor villages were higher then followed by poor cities, rich cities, and rich villages. When there is a change in income, poor rural households and poor cities when the public still responds by allocating a large part of their budgets to very basic trade such as other food and tobacco, rice, other oils, and household fats in rich villages and rich cities provide more responses to allocating their incomes to the trade in meat, fruits, vegetables, fish, eggs, milk, and processed foods.

 

Keywords: Quadaric Almost Ideal System, income elasticity, consumption, demand food
SELF-SIMILAR STRUCTURES IN BIOMECHANICS. HUMAN VIBRORECEPTORS
Authors: Banakh L.Ya.
Published: July 2021

The concept of dynamic-fractal self-similar structures (dynamic fractal) is introduced. This concept consists in scaling the dynamic, i.e. elastic-inertial parameters of the forming cells. It is shown that a dynamic fractal decreasing in length amplifies the incoming signal along the structure. A dynamic fractal that increases in length, on the contrary, has the good vibroisolation properties, the attenuation intensity in which is higher than in the periodic structure. The dynamic properties of the Pacini corpuscle, which is a human vibration detector, are investigated. Its mechanical model is constructed. It is shown that the vibroreceptor is a dynamic fractal with parameters decreasing in length. Therefore the vibroreceptor amplifies the incoming signal, which makes it possible to detect even weak vibration effects on a person
Sustainable Natural Resource Management to Ensure Strategic Environmental Development
Authors: Koval Viktor , Mikhno Inesa , Udovychenko Iryna , Gordiichuk Yevgeniia , Kalina Iryna
Published: July 2021

The article reveals the issue of irrational use of natural resources in Ukraine that affects public health, population working ability and macroeconomic performance. It has been found that heavier responsibility of each individual and changes in values can improve the current situation. It is concluded that the general utility function can be increased by rational nature management and implementation of the development strategy minimizing such negative risk factors as ecological state deterioration, inefficient functioning of the healthcare system, excessive use of chemical compounds while producing agricultural products, etc. The key in the study is the formation of a holistic view of the relationship between pollution and the state of the environment and harm to public health based on the analysis of rational nature management and environmental pollution and their negative impact on environmental health. A model has been developed that takes into account the negative environmental impact on health and the investment that is necessary to be healthy and stay productive.
MOLECULAR PROPERTIES, BIOACTIVITY SCORES, AND TOXICITY PREDICTIONS OF THE PHYTOCONSTITUENTS PRESENT IN BAUHINIA ACUMINATA
Authors: Kudumula Neelima , Divya Noota , Sravika Nagamalla , Priya Saketha , Anusha Pachava , Sai Jyotsna Mudavath
Published: July 2021

ABSTRACT:

To develop the herbal drug with the least side effects, there are superior opportunities to discover the medicinal and other biological properties. Natural products serve as sources of beneficial chemical molecules. For this study, Bauhinia acuminata an important medicinal plant of the Indian subcontinent that belongs to the family Fabaceae was chosen. The plant is well known for its precautionary action in tuberculosis. It has been established to possess some pharmacological activities such as membranes Stabilizing activity1, antibacterial2, anti-nociceptive3, thrombolytic activity4, antioxidant5, anthelmintic6, anti-diarrheal7, Hepato-protective 8.

 Phytoconstituents present in Bauhinia acuminata obey Lipinski's rule (MiLog P <5) except Kaempferol-3-glucoside indicated their drug-likeness property. Rhoeagenine, 9, 12, 15-octadecatrienoic acid, and 9, 12-octadecadienoic acid are the phytoconstituents showing all types of binding with all types of receptors binding except Kinase inhibitor activity.

Rhoeagenine, Alpha humulene, 9, 12, 15-octadecatrienoic acid, 9, 12-octadecadienoic acid, Alpha muurolol, Beta-sitosterol, Kaempferol-3-glucoside are the phytoconstituents that are free from any type of toxicity. The accurate prediction scores can be used as monographs by researchers and scientists for the development of potential Semisynthetic and synthetic drugs for multifarious usage.
ELECTROCHEMICAL TREATMENT OF PARTS OBTAINED BY SELECTIVE LASER FUSION
Authors:   Federal State Unitary Enterprise «All-Russian Scientific Research Institute of Aviation Materials», Nikiforov A.A. , Demin S.A. ,   Federal State Unitary Enterprise «All-Russian Scientific Research Institute of Aviation Materials», Khmeleva K.M. ,   Federal State Unitary Enterprise «All-Russian Scientific Research Institute of Aviation Materials»
Published: July 2021

The use of additive technologies for the production of parts is one of the main trends in recent years in the field of industrial production. Application of the technology of «layer-by-layer growing» provides savings in materials, a significant reduction in labor intensity, and allows you to create parts of any complexity and configuration. To reduce the surface roughness values of parts manufactured using additive technology, the authors proposed a method of electrochemical treatment in acid electrolytes, which makes it possible to achieve a decrease in surface roughness values by more than 5 times compared to the original one, and to process parts of any complexity and configuration.
COMPUTATIONAL AND EXPERIMENTAL STUDY OF THE EFFECTIVE THERMAL CONDUCTIVITY OF FIBROUS MATERIALS
Authors:   Federal State Unitary Enterprise «All-Russian Scientific Research Institute of Aviation Materials», Vorobev N.N. , Barinov D.Ya. ,   Federal State Unitary Enterprise «All-Russian Scientific Research Institute of Aviation Materials», Zuev A.V. ,   Federal State Unitary Enterprise «All-Russian Scientific Research Institute of Aviation Materials», Pakhomkin S.I. ,   Federal State Unitary Enterprise «All-Russian Scientific Research Institute of Aviation Materials»
Published: July 2021

The article is devoted to the evaluation of the effect of porosity on the effective thermal conductivity of thermal insulation materials. The main factors influencing the thermal conductivity of the material, such as density, the type of porous structure of the material and humidity, are considered. The method of measuring the thermal conductivity by the stationary heat flow method and the hot zone method is described. A method for calculating the effective thermal conductivity of fibrous materials is presented. A computational and experimental study of the effective thermal conductivity is carried out and the results are analyzed.
Soluble Transferrin Receptor and Soluble Transferrin Receptor/Log Ferritin Ratio are Correlated with Iron Status in Regular Hemodialysis Patients
Authors: Kandarini Yenny , Mahadita Gede Wira , Herawati Sianny , Lestari Anak Agung Wiradewi , Suega Ketut , Widiana I Gde Raka
Published: July 2021

BACKGROUND: Monitoring of iron status in chronic kidney disease patients is important, however inflammation may hinder its monitoring. Soluble transferrin receptor (sTfR) is an alternative parameter to overcome this issue, whereas ferritin play a part in the inflammation process. Hence, the correlation between the sTfR ratio and the sTfR/log ferritin ratio with conventional iron status parameters in regular hemodialysis patients is necessary to be evaluated.METHODS: A cross-sectional was conducted in the current study. As many as 5 mL of blood (2 mL for sTfR and 3 mL for serum iron and ferritin levels) was collected. sTfR level was the blood-soluble transferrin receptor level measured by the enzyme-linked immunosorbent assay (ELISA). The amount of ferritin and serum iron was determined using the immunochemiluminescent process. To evaluate the correlation, the Pearson correlation test was used.RESULTS: A total of 80 subjects was included in this study. The mean of hemoglobin was 10.25±1.66 g/dL, serum iron was 58.19±26.56 g/dL, and the median ferritin was 520.4 (49.9-3606) ng/mL. The sTfR was significantly associated only with serum iron levels with a correlation coefficient of r=-0.242; p=0.031. The sTfR/log ferritin was significantly associated with serum iron l evels (InSI)(r=-0.255, p=0.022); and transferrin saturation (r=-0.295; p=0.008).CONCLUSION: sTfR/log ferritin has a negative and significant correlation with serum iron levels and transferrin saturation, while sTfR negatively correlated with serum iron levels. sTfR and sTfR/log ferritin may be considered as an alternative iron marker in inflammation setting such as CKD.KEYWORDS: sTfR/log ferritin, iron status, serum iron, ferritin, chronic kidney disease, hemodialysis
Coffea canephora Bean Extract Induces NIH3T3 Cell Migration
Authors: Ariesanti Yessy , Sandra Ferry , Claresta Bianda , Alvita Livia
Published: July 2021

BACKGROUND: Wound healing is an essential biological process that consists of sequential steps aimed at restoring the architecture and function of damaged cells and tissues. There are empirical evidences of using pure coffee bean powder as an alternative medicine in treating various types of wounds. However, there is limited data on coffee-induced wound healing, especially migration of cells. Therefore, current study was conducted to investigate the role of coffee extract in cell migration, especially fibroblast which is important for wound healing.METHODS: Coffea canephora beans were prepared, extracted and added in the NIH3T3 cell culture in final concentration of 2.5% and 5%. Then cytotoxicity test was performed using Na,30-[(phenylamino)-carbonyl]-3,4-tetrazolium]-bis(4-methoxy-6-nitro) benzenesulfonic acid hydrate (XTT) assay. Meanwhile, cell migration test was performed with scratch assay. All results were statistically analyzed.RESULTS: The 2.5% or 5% Coffea canephora beans extract (CCBE)-treated NIH3T3 cell numbers were almost similar with the numbers of NIH3T3 cells in starvation medium merely. Meanwhile, 2.5% and 5% CCBE showed significant decrease of the widths of scratched areas compared to starvation medium merely (ANOVA with LSD Post-hoc, p=0.000). After 24 h and 48 h, the average widths of 2.5% and 5% CCBE-treated scratched areas were 235.68±22.79, 50.36±5.29, 229.95±23.01, 27.68±2.83, respectively.CONCLUSION: Since both 2.5% and 5% CCBE are potential in inducing migration of fibroblast (NIH3T3 cell) and do not induce cytotoxicity, the CCBE could be potential as an agent for wound healing.KEYWORDS: coffee, Coffea canephora, NIH3T3, migration, cytotoxicity
Augmenting Feeding Value of Rice Distillers Dried Grain with Solubles Through Dietary Addition of Enzymes in Broilers
Authors: Dinani O.P. , Tyagi Pramod K. , Mandal A.B. , Tyagi Praveen K. , Bhanja S.K. , Dutta N.
Published: July 2021

Background: Substitution of expensive protein sources like soybean meal with lower cost ingredient like rice distillers dried grain with solubles (rDDGS) would reduce the cost of the feed. Various enzymes supplementation may be used to increase their inclusion level. Methods: An in-vivo study of 42 days was undertaken (n= 384) in broilers divided into 12 dietary treatments as per 3x4 factorial design. Two levels of rDDGS consisted of 12.5 and 15% without and with three different types of enzymes xylanase, protease and multienzymes were used to find out substract specific enzyme. Result: Overall the growth performance of broiler chicken was significantly lower at 15% rDDGS level as compared to control and 12.5% rDDGS level. However, it was significantly (P less than 0.01) improved by supplementation of any of the three enzymes (xylanase, protease and multienzymes) in 12.5 and 15% rDDGS groups. Nitrogen retention, dry matter and energy metabolizability were significantly (P less than 0.01) improved in all enzymes supplemented groups. The cost of feed per kg live weight and meat yield was significantly (P less than 0.01) lower at 12.5% rDDGS with enzymes supplementation. Thus, it is concluded that the enzymes supplementation can increase inclusion level of rDDGS from 12.5 to 15% for economic broiler production.
Influence of Priming with Exogenous Selenium on Seed Vigour of Alfalfa (Medicago sativa L.)
Authors: Xia F.S. , Wang C.C. , Li Y.Y. , Yang Y.Y. , Zheng C. , Fan H.F. , Zhang Y.D.
Published: July 2021

Background: Selenium (Se) is an essential trace element to higher plants, animals and humans, but low Se levels are a global public health concern. Seed priming has become a basic strategy for the production of Se-riched agricultural products, but its application is still not clear in the production of Se-enrich alfalfa, hence this study was conducted for the production of Se-enriched alfalfa by seed priming with different concentrations and time on seed vigour. Methods: Seeds were primed with 0, 0.5, 1.0, 2.0, 4.0 and 8.0 mmol L-1 of sodium selenite solution for 0, 3, 6, 9 and 12 h at 20°C and their germination percentage, germination index, seedling vigour index and mean germination time were analyzed. Result: Seed vigour of alfalfa was improved by priming with low selenium (Se) concentration (0.5 and 1.0 mmol L-1), but was inhibited by high Se concentration ( greater than 2.0 mmol L-1). Hence, it must be necessary to carefully select appropriate concentration and time for the application of Se priming in alfalfa seeds. The optimal manner of Se priming in alfalfa seeds might be at 1.0 mmol L-1 concentration for 9 h.
Spatial and temporal thresholds in installation art: Jan van der Merwe’s Eclipse
Authors: Combrink Louisemarié
Published: July 2021

The notion of thresholds and their potential to suggest liminality is usually associated with spatialities. However, I contend this notion can be extended to layered temporal thresholds and temporal liminalities. I present this argument, using postclassical narratological concepts as theoretical framework, with reference to the South African artist Jan van der Merwe’s installation artwork Eclipse (2002). In this work, various spatial thresholds can be distinguished that relate to issues of conflict, mourning, exclusion, surveillance and the suggestion of death. This is achieved by means of a no man’s land experienced when entering the artwork, where the viewer-participant finds him or herself compelled to follow a footpath surrounded by barbed wire on which clothes made of rusted metal are suspended. This journey culminates in a wall that presents three screens showing rose petals being dropped, as if into a grave. Various possible places suggest themselves: refugee camps, concentration camps, war zones and a cemetery. I argue that these spatialities are made possible by temporal thresholds that accompany them. Apart from the patina of the rusted material that suggest the passing of time, the moving flower petals in the screens repeat constantly to create not only liminal temporalities in terms of the artwork at large, but also an iterative sense of the ongoing culmination of these temporalities in death. Opsomming Die idee van drempels en hul potensiaal om die liminale te suggereer word tipies met ruimtelikhede geassosieer. Desnieteenstaande voer ek aan dat hierdie gedagte verbreed kan word na gelaagde tydmatige drempels en tydmatige liminaliteite. Ek bied hierdie argument vanuit die kader van postklassieke narratologie as teoretiese raamwerk en met verwysing na die Suid-Afrikaanse kunstenaar Jan van der Merwe se installasiekunswerk Eclipse (2002). In hierdie werk kan ŉ aantal tydmatige drumpels onderskei word wat telkens kwessies van konflik, bewening, uitsluiting, dophou en die suggestie van dood aan die hand doen. Dit word bewerkstelling deur die ervaring van ŉ niemandsland wanneer die kunswerk betree word, omdat die aanskouer-deelnemer noodgedwonge ŉ voetpaadjie moet volg wat deur doringdraad omhul is en waarop klere wat uit geroeste metaal gesuspendeer is. Hierdie reis kulmineer in ŉ muur waarop drie skerms gemonteer het wat roosblare toon, asof in ŉ graf. Daar word gesinspeel op verskeie moontlike plekke: vlugtelingkampe, konsentrasiekampe, oorloggebiede en ŉ begraafplaas. Ek voer aan dat hierdie ruimtelikhede moontlik gemaak word deur tydmatige drumpels wat hand aan hand met die ruimtes gesuggereer word. Benewens die patina van die geroeste materiaal wat verband hou met die verloop van tyd, stel die herhalende beweging van die blomblare in die skerms ook liminale tydsfere aan die orde binne die kunswerk as geheel, en dryf ook – op iteratiewe wyse – hierdie tydsfere op die spits om ŉ suggestie van die dood aan die hand te doen.
A New Probability Distribution for Modeling Failure and Service Times: Properties, Copulas and Various Estimation Methods
Authors: Elgohari Hanaa , Ibrahim Mohamed , Yousof Haitham
Published: July 2021

In this paper, a new generalization of the Pareto type II model is introduced and studied. The new density canbe “right skewed” with heavy tail shape and its corresponding failure rate can be “J-shape”, “decreasing” and “upside down (or increasing-constant-decreasing)”. The new model may be used as an “under-dispersed” and “over-dispersed” model. Bayesian and non-Bayesian estimation methods are considered. We assessed the performance of all methods via simulation study. Bayesian and non-Bayesian estimation methods are compared in modeling real data via two applications. In modeling real data, the maximum likelihood method is the best estimation method. So, we used it in comparing competitive models. Before using the the maximum likelihood method, we performed simulation experiments to assess the finite sample behavior of it using the biases and mean squared errors.
Local Stability Dynamics of Equilibrium Points in Predator-Prey Models with Anti-Predator Behavior
Authors: Harianto Joko , Suparwati Titik , Dewi Alfonsina Lisda Puspa
Published: July 2021

This article describes the dynamics of local stability equilibrium point models of interaction between prey populations and their predators. The model involves response functions in the form of Holling type III and anti-predator behavior. The existence and stability of the equilibrium point of the model can be obtained by reviewing several cases. One of the factors that affect the existence and local stability of the model equilibrium point is the carrying capacity (k) parameter. If x3∗, y3∗  > 0 is a constant solution of the model and ∈ (0,x3∗), then there is a unique boundary equilibrium point Ek (k , 0). Whereas, if k ∈ (x4∗, y4∗], then Ek (k, 0) is unstable and E3 (x3∗, y3∗) is stable. Furthermore, if k ∈ ( x4∗, ∞), then Ek ( k, 0) remains stable and E4 (x4∗, y4∗) is unstable, but the stability of the equilibrium point E3 (x3∗, y3∗) is branching. The equilibrium point E3 (x3∗, y3∗) can be stable or unstable depending on all parameters involved in the model. Variations of k parameter values are given in numerical simulation to verify the results of the analysis. Numerical simulation indicates that if k = 0,92 then nontrivial equilibrium point Ek (0,92 ; 0) stable. If k = 0,93 then Ek (0,93 ; 0) unstable and E3∗(0,929; 0,00003) stable. If k = 23,94, then Ek (23,94 ; 0) and E3∗(0,929; 0,143) stable, but E4∗(23,93 ; 0,0005) unstable. If k = 38 then Ek(38,0) stable, but E3∗(0,929; 0,145) and E4∗(23,93 ; 0,739) unstable.Keywords: anti-predator behavior, carrying capacity, and holling type III.
Keberadaan Perpustakaan Pusat Universitas Padjajaran Selama Masa Pandemi Covid-19
Authors: Sarah Maula Siti , - Sukaesih - , Rukmana Evi Nursanti , - Samson CMS -
Published: July 2021

Artikel ini bertujuan untuk mendeskripsikan peranan serta keberadaan Perpustakaan Pusat Unpad selama masa pandemi covid-19 untuk memenuhi kebutuhan informasi pemustaka dengan memperhatikan berbagai aspek-aspek penting yang terdapat di dalam sistem perpustakaan. Penelitian ini menggunakan metode deskriptif kualitatif dengan teknik pengambilan data wawancara dan kajian literatur. Data yang digunakan oleh penulis ialah data mengenai sistem layanan perpustakaan serta tantangan yang dihadapi diikuti oleh inovasi sebagai solusi. Hasil penelitian ini merujuk pada sebuah kesimpulan bahwa Perpustakaan Pusat Unpad menghadapi berbagai macam jenis tantangan mulai dari aspek layanan, koleksi, hingga pembagian jam kerja pegawai perpustakaan. Adapun inovasi yang dilakukan oleh pihak Perpustakaan Pusat Unpad untuk tetap dapat melayani pemustaka secara maksimal adalah dengan memberikan Layanan Pustakawan "Subject Specialist" serta melakukan promosi atau pemasaran terkait kegiatan, layanan, dan fasilitas perpustakaan melalui sosial media Instagram.
PENGARUH PEMBIAYAAN BANK SYARIAH TERHADAP NILAI OUTPUT UMKM: ANALISIS DATA PANEL
Authors: Alghifary Muhammad Syauqy , Kadji Dzuliyati , Kornitasari Yenny
Published: July 2021

ABSTRAKPenelitian ini bertujuan untuk menganalisis pengaruh perbankan syariah terhadap nilai output UMKM di Indonesia melalui pengujian terhadap pengaruh pembiayaan modal kerja dan investasi bank syariah terhadap nilai output UMKM. Penelitian ini menggunakan pendekatan kuantitatif dengan mengolah data sekunder yang bersifat data panel. Sampel dari data cross section mencakup 33 provinsi di Indonesia dan sampel dari data time series yang bersifat tahunan mengambil rentang waktu tahun 2017-2019. Penelitian ini melibatkan dua variabel kontrol berupa Dana Pihak Ketiga (DPK) dan jumlah tenaga kerja Industri Mikro Kecil di Indonesia. Hasil pengujian menunjukkan bahwa secara simultan variabel pembiayaan modal kerja bank syariah, pembiayaan investasi bank syariah, DPK dan jumlah tenaga kerja berpengaruh signifikan terhadap nilai output UMKM di Indonesia tahun 2017-2019. Maka produk pembiayaan bank syariah dinilai efektif dalam meningkatkan nilai output UMKM.Kata kunci: Pembiayaan Modal Kerja, Pembiayaan Investasi, Bank Syariah, Nilai Output, UMKM. ABSTRACTThis study aims to analyze the effect of Islamic banking on the output value of MSMEs in Indonesia through testing the effect of working capital financing and Islamic bank investment on the output value of MSMEs. This study uses a quantitative approach by processing secondary data that is panel data. The sample of the cross section data covers 33 provinces in Indonesia and the sample of time series data which is annual takes the time span 2017-2019. This study involved two control variables in the form of Third Party Funds (DPK) and the number of workers in the Micro and Small Industry in Indonesia. The test results show that simultaneously the variables of Islamic bank working capital financing, Islamic bank investment financing, DPK and the number of workers have a significant effect on the output value of MSMEs in Indonesia in 2017-2019. So Islamic bank financing products are considered effective in increasing the output value of MSMEs.Keywords: Working Capital Financing, Investment Financing, Islamic Bank, Output Value, MSMEs.
Additions to Annonaceae in the Flora of Thailand
Authors:   Department of Botany and Microbiology, Ohio Wesleyan University, Delaware, Ohio 43015, USA., Johnson David M. , Bunchalee Pasakorn ,   Department of Biology, Faculty of Science, Mahasarakham University, Kantarawichai District, Maha Sarakham 44150, Thailand., Chalermglin Piya ,   Agricultural Technology Department, Thailand Institute of Scientific and Technological Research, Khlong Luang District, Pathum  Thani 12120, Thailand., Chantaranothai Pranom ,   Department of Biology, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand., Leeratiwong Charan ,   Division of Biological Science, Faculty of Science, Prince of Songkla University, Hatyai, Songkhla 90112, Thailand., Murray Nancy A. ,   Department of Botany and Microbiology, Ohio Wesleyan University, Delaware, Ohio 43015, USA., Saunders Richard ,   Division of Ecology & Biodiversity, School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong, China., Sirichamorn Yotsawate ,   Department of Biology, Faculty of Science, Silpakorn University, Sanam Chandra Palace Campus, Nakhon Pathom 73000, Thailand., Su Yvonne ,   Duke-NUS Medical School Singapore, 8 College Road, 169857 Singapore., Sutthisaksopon Phanom ,   Faculty of Environmental Culture and Ecotourism, Srinakharinwirot University, Bangkok 10110, Thailand.
Published: July 2021

Work toward completion of the Annonaceae treatment for the Flora of Thailand revealed 18 species previously unrecorded for the country, six of them in the genus Fissistigma. In addition, several species previously placed in synonymy are re-instated, for which we propose three new combinations in the genera Mitrella, Monoon, and Sphaerocoryne.
Tor Hidden Services: A Systematic Literature Review
Authors: Huete Trujillo Diana Lissette , Ruiz-Martínez Antonio
Published: July 2021

Anonymous communications networks were born to protect the privacy of our communications, preventing censorship and traffic analysis. The most famous anonymous communication network is Tor. This anonymous communication network provides some interesting features, among them, we can mention user’s IP location or Tor Hidden Services (THS) as a mechanism to conceal the location of servers, mainly, web servers. THS is an important research field in Tor. However, there is a lack of reviews that sump up main findings and research challenges. In this article we present a systematic literature review that aims to offer a comprehensive view on the research made on Tor Hidden services presenting the state of the art and the different research challenges to be addressed. This review has been developed from a selection of 57 articles and present main findings and advances regarding Tor Hidden Services, limitations found, and future issues to be investigated.
Epigenetic Alterations in Pediatric Sleep Apnea
Authors: Cheung Emily Catherine , Kay Matthew Wyatt , Schunke Kathryn Jaques
Published: July 2021

Pediatric obstructive sleep apnea (OSA) has significant negative effects on health and behavior in childhood including depression, failure to thrive, neurocognitive impairment, and behavioral issues. It is strongly associated with an increased risk for chronic adult disease such as obesity and diabetes, accelerated atherosclerosis, and endothelial dysfunction. Accumulating evidence suggests that adult-onset non-communicable diseases may originate from early life through a process by which an insult applied at a critical developmental window causes long-term effects on the structure or function of an organism. Recently, much attention has been paid to the role of epigenetic mechanisms in the pathogenesis of adult disease susceptibility. Epigenetic mechanisms that influence adaptive variability include histone modifications, non-coding RNAs, and DNA methylation. This review will highlight what is currently known about the phenotypic associations of epigenetic modifications in pediatric OSA and will emphasize the importance of epigenetic changes as both modulators of chronic disease and potential therapeutic targets.
Inconsistency of Time-symmetry Model
Authors: Šorli Srečko , Čelan Štefan
Published: July 2021

Can physical objects be in time-symmetry? Physical objects can only exist in a medium that has physical attributes, which means this medium is a type of energy. Is time energy? This article will show that time is not energy and there is no possibility that physical objects could be in time-symmetry. Physical objects only can be in symmetry in the time-invariant space in which they exist. In this perspective time measured with clocks is the result of the observer’s measurement in the time-invariant space. The time-symmetry model is flawed.
Perioperative Outcome in Dogs Undergoing Emergency Abdominal Surgery: A Retrospective Study on 82 Cases (2018-2020)
Authors: Fages Aida , Soler Carme , Fernández-Salesa Nuria , Conte Giuseppe , Degani Massimiliano , Briganti Angela
Published: July 2021

Emergency abdominal surgery carries high morbidity and mortality rates in human medicine; however, there is less evidence characterizing the outcome of these surgeries as a single group in dogs. The aim of the study was to characterize the clinical course, associated complications and outcome of dogs undergoing emergency abdominal surgery. A retrospective study was conducted. Dogs undergoing emergency laparotomy were included in the study. Logistic regression analysis was performed to identify variables correlated with death and complications. Eighty-two dogs were included in the study. The most common reason for surgery was gastrointestinal foreign body. Overall 15-day mortality rate was 20.7% (17/82). Median (range) length of hospitalization was 3 (0.5 - 15) days. Of the 82 patients, 24 (29.3%) developed major complications and 66 (80.5%) minor complications. Perioperative factors significantly associated with death included tachycardia (P < 0.001), hypothermia (P < 0.001), lactate acidosis (P < 0.001), shock index > 1 (P < 0.001), leukopenia (P < 0.001), thrombocytopenia (P < 0.001) at admission; intraoperative hypotension (P < 0.001) and perioperative use of blood products (P < 0.001). The results of this study suggest that mortality and morbidity rates after emergency abdominal surgery in dogs are high.
Doxycycline and Minocycline act as Positive Allosteric Modulators of the PAC1 Receptor and Induce Plasminogen Activators in RT4 Schwann Cells
Authors: Thomas Broome Sarah , Musumeci Giuseppe , Castorina Alessandro
Published: July 2021

Regeneration of peripheral nerves depends on the ability of axons to navigate through an altered extracellular environment. It has been suggested that Schwann cells facilitate this process through their secretion of neuropeptides and proteases. Using the RT4-D6P2T Schwann cell line (RT4), we have previously shown that RT4 cultures endogenously express the neuropeptide PACAP, and respond to exogenous stimulation by inducing the expression of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA) through PAC1 receptor activation. In this study, based on recent findings showing that doxycycline and minocycline act as positive allosteric modulators (PAMs) of the PAC1 receptor, we tested if treatment with these tetracyclines could induce the expression and activity of tPA and uPA in RT4 cells. Using ELISA and zymographic analyses, we demonstrate that doxycycline and minocycline reliably induce the secretion and activity of both tPA and uPA, which is paralleled by an increased expression levels, as shown by immunocytochemistry and Western blots. These actions were mediated, at least in part, by the PAC1 receptor, as PACAP6-38 mitigated tetracycline-induced expression and activity of tPA and uPA. We conclude that doxycycline and minocycline can act as PAMs of the PAC1 receptor to promote proteolytic activity in RT4 cells.
Bovine Babesiosis and Distribution of Ixodid Ticks in Dasenech and Salamago District, Southern Ethiopia
Authors: Gebremeskel Haben Fesseha , Abose Mesfin Mathewos , Bekele Eyob Eshetu , Chido Bereket Tefera
Published: July 2021

Background: Babesiosis and its tick carriers cause serious problems for cattle and are among the common protozoan blood parasites in Ethiopia. Methods: A cross-sectional survey was conducted from September 2019 to August 2020 to identify babesiosis in cattle and its tick vectors in extensively managed livestock in Dasenech and Salamago District South Omo Ethiopia. A total of 470 blood samples were collected for identification of hemoparasite using a thin blood smear followed by the Giemsa staining method and Packed Cell Volume (PCV) determination for detection of anemia. Results: Accordingly, the overall prevalence of bovine babesiosis in the study districts were 21.7% and Babesia bigemina (15.53%) and B. bovis (6.17%) were identified during this study. Factors such as age, sex, body condition score, season, tick burden, and level of tick Infection were considered as risk factors; yet, the season and level of tick Infection were found significantly associated (p< 0.05) with the occurrence of babesiosis. Besides, the mean PCV value of infected cattle (21.49%) was lower than non-infected animals (28.29%) which shows there was a strong correlation (p=0.0001) between anemia and Babesiosis. The prevalence of tick Infection was 86.17% (405/470) and a total of 8040 ticks adult ticks belonging to four tick genera namely Amblyomma (32.34%), Boophilus (18.51%), Hyalomma (18.94%), and Rhipicephalus (16.38%) were identified and all have a significant role (p< 0.05) on the occurrence of babesiosis in cattle. Conclusion: Bovine babesiosis is an important hemoparasitic protozoan disease of cattle in the study areas. To address and manage the problem, nearby veterinary service systems need to diagnose blood parasites and provide alternatives, especially for tick-borne diseases. Also, it is essential to customize appropriate and integrated tick control measures and tactical treatment of overt bovine babesiosis clinical cases.
THE FALLACY OF ORGANIC AND CONVENTIONAL FRUIT AND VEGETABLE PRICES IN THE METROPOLITAN REGION OF CAMPINAS, SÃO PAULO, BRAZIL
Authors: Watanabe Maria Aico , De Abreu Lucimar Santiago , Luiz Alfredo José Barreto
Published: July 2021

There is a popular myth or fallacy based on the idea that organic fruits and vegetables are always more expensive than conventional products. To assess whether this statement is true, a qualitative and quantitative research was conducted between September and December 2017, involving four supermarkets and seven outdoor markets, located in Campinas, in the State of São Paulo, Brazil. This statement was confirmed for the research conducted in supermarkets, but not for outdoor markets, where some organic products are cheaper than conventional ones. In fact, supermarkets sell organic products at higher prices and, normally, only the upper middle class has access to the products, but the consumer will have the option to buy conventional products at lower prices. Conventional supermarket products serve a larger number of consumers, including those with lower incomes. Most outdoor market traders are farmers who sell their own harvested products. Thus, these producers set their own prices, which are more attractive to the consumer; however, prices may vary. Due to price differences between supermarkets and free markets, consumers in general, and especially low-income consumers, obtain affordable, healthy, fresh and seasonal products, especially in outdoor markets. It is concluded that the best option for the low-income consumer is to buy organic products in open-air markets, since in these locations’ prices are generally cheaper, the products are healthier and fresher. The consumer also has access to diverse "seasonal" products, which are even cheaper and fresher are offered throughout the year, thus allowing the consumer to have a healthy and diverse diet throughout the year.
Pelatihan Membuat Game Menggunakan Software Construct 2 untuk Meningkatkan Motivasi Belajar pada Siswa SMK
Authors: Suliswaningsih Suliswaningsih , Widiawati Chyntia Raras Ajeng , Syafa'at Alif Yahya , Fajrina Bela Tyara Nur
Published: July 2021

Bermain game secara berlebihan dapat menimbulkan dampak yang merugikan. Salah satu dampak negatif yang dapat ditimbulkan dari bahaya kecanduan game adalah dari segi waktu yang dapat mempengaruhi motivasi dan prestasi belajar siswa. Waktu luang yang seharusnya digunakan untuk mendalami materi pelajaran sekolah justru dihabiskan untuk menyelesaikan level demi level dalam permainan video game. Siswa Sekolah Menengah Kejuruan merupakan salah satu pengguna permainan (games), baik laki-laki maupun siswa perempuan. Usia siswa dapat diarahkan pada kegiatan yang lebih produktif. Ketertarikan para siswa dalam bermain game dapat dimanfaatkan sebagai motivasi dalam belajar. Sehingga siswa tidak hanya sebagai pengguna tetapi dapat diarahkan untuk membuat game secara mandiri. Namun sebagian besar jurusan di SMK merupakan jurusan yang tidak berorientasi pada profesi programmer, sehingga siswa belum memiliki pengetahuan tentang pemrograman game. Hal ini tentu menjadi permasalahan bagi siswa untuk membuat game secara mandiri. Tujuan pengabdian ini adalah memberikan pelatihan membuat game pilah sampah organik dan sampah anorganik tanpa coding menggunakan perangkat lunak Construct 2. Adapun metode pelaksanaannya antara lain dilakukan observasi untuk menganalisis kebutuhan mitra, permasalahan mitra, perancangan serta penawaran solusi, pelaksanaan kegiatan utama, hingga tahap pelaporan kegiatan. Hasil dari pelatihan adalah pengetahuan dan pemahaman tentang logika dasar pemrograman game dalam bentuk permainan pilah sampah organik dan anorganik berbasis android.
Evaluation of Radiographic Outcomes after Core Decompression for Osteonecrosis of the Femoral Head: The Beijing University of Chinese Medicine X-ray Evaluation Method
Authors: Huang Zeqing , Li Taixian , Lin Na , Cui Quanjun , Chen Weiheng
Published: July 2021

Background:

Joint-preserving treatments for osteonecrosis of the femoral head (ONFH) are an area of significant interest in orthopaedics as they may restore function and provide durable benefit to patients who would otherwise require early total hip arthroplasty. Studies reporting the outcomes for these procedures generally rely on a combination of radiographic and clinical outcomes. However, there is not currently a standardized radiographic scoring system that allows for objective reporting of radiographic outcomes following these procedures. This article introduces a novel scoring system (Beijing University of Chinese Medicine X-ray evaluation, BUCMXE) based on Anteroposterior (AP) hip radiographs to allow for objective evaluation and comparison of postoperative outcomes following joint-preserving treatments for ONFH.

Methods:

The proposed scoring system utilizes AP radiographs of the hip and consists of a total score (0-10) derived from the sum of subscores in 3 domains: femoral head morphology, osteonecrotic lesion, and degree of osteoarthritis. Each radiographic parameter is scored from 0 (normal) to 3 or 4 (advanced disease). The scoring model was retrospectively applied to a cohort of patients who had undergone core decompression and cancellous bone grafting procedures by the principal investigator.

Results:

The BUCMXE provided a clear and reproducible means of quantifying and communicating radiographic changes over the course of follow-up in our study cohort. Statistical analysis demonstrated that the BUCMXE was sensitive to detect the radiographic changes associated with the index procedure. The median total score was reduced from 3 preoperatively to 2 at the initial (3-month) follow-up for this cohort. This change was attributable to the obvious improvement of osteonecrotic lesion in patients who had more advanced disease at the time of their procedure.

Conclusion:

The BUCMXE system allowed for objective quantification of radiographic changes following joint-preserving hip surgery in our cohort. Statistical analysis of BUCMXE scores demonstrated that the scoring system was sensitive to detect subtle radiographic changes associated with disease progression in the follow-up period.

Level of Evidence:

TherapeuticLevel III.