bluuebunny/crossref_metadata_2025 huggingface dataset:
Metabolomics and biomarkers for lupus nephritis – a systematic review
Authors: Barone Felippe Pereira , Lourenço Silvia Vanessa , Azevedo Luiz Sergio , de Souza Mayara Nanci , Coutinho-Camillo Claudia Malheiros , Florezi Giovanna Piacenza
Published: September 2023

Background

The development of personalized medicine using high-throughput methods, such as metabolomics profiling, in discovering and validating biomarkers, may play a key role in the development of new and non-invasive methods for diagnosis and understanding of lupus nephritis (LN).

Objectives

The aim of this systematic review was to present the current status of metabolomics discovery of biomarkers applied to diagnosing, staging, understanding and treating LN.

Methods

The review was made according to PRISMA guidelines, searching for keywords associated to “Lupus”, “Lupus nephritis”, “Metabolomics” and their variants, with no language restriction, in PUBMED, MEDLINE and EMBASE databases. Full-texts and primary studies in humans including the topics of lupus erythematosus and/or lupus nephritis and used metabolomics in urine and serum as a research method, were included and data analysis was performed individually.

Results

The search revealed multiple candidates for the diagnosis, staging and prognosis of lupus nephritis, such as citrate, acetate, N-acetyl glycoproteins and various amino acids, as their level in the biofluids of LN patients found in the studies are consistent with the known pathophysiology of LN and inflammatory processes.

Conclusions

The study of metabolomics associated with LN still needs further investigation concerning metabolic pathways and pathogeny. As the community building the databases for the research and annotation of metabolites grow, the use of serum, urine, and saliva in metabolomic profiling, may become a potential non-invasive method in translational medicine studies.
Early stent fractures in superficial femoral artery resulting multiple pseudoaneurysm formation within one year: a case report
Authors: Benedict Taylor , Hassan Esraa , Mir Mikael , Boike Sydney , Gao Jidi , Khan Syed Anjum
Published: September 2023

Background

Though fracture is known complication of stenting, pseudoaneurysm asscoiated with stent fracture is an extremely rare complication. This has previoulsy been described to occur at least one or more years following initial stent placement. Here we present a case of multi-site stent fracture leading to two separate SFA pseudoaneurysms within one year of placement, successfully treated with covered stents.

Case presentation

A 72-year-old male presented with severe claudication of his left lower extremity (Rutherford 3), found to have long segment SFA chronic total occlusion (CTO). Patient successfully underwent endovascular revascularization. Follow-up duplex ultrasound (US) at one year demonstrated a focus of severe in-stent restenosis (ISR). During repeat angiogram for treatment of the stenosis, stent fracture and pseudoaneurysm was seen in the distal SFA, which was treated successfully with a self-expanding covered stent. Additional stent fractures and pseudoanerusyms were subseuqently identified on follow-up, necessitating a third angiogram, and these were successfully repaired using overlapping covered stents, without further recurrence.

Conclusions

Superficial femoral artery stent fractures leading to pseudoaneurysms are extremely rare, particularly within first year of stent placement. Endovascular repair with covered stents has proven to be an effective treatment option with decreased procedural morbidity compared to surgical repair.
Pleomorphic adenomia of lower lip: A case report
Authors: Akram Muhammad Usman , Hasham Nausheen , Atique Hafsa , Raza Ahmad
Published: September 2023

Pleomorphic adenoma is a benign tumor of the salivary glands. It commonly occurs in the parotid gland, palate, upper lip and cheek. The authors present a rare case of a pleomorphic adenoma of the lower lip in a 30 years old female admitted on 20th of July, 2022 at Akbar Niazi Teaching Hospital, Islamabad with a complaint of painless, slightly itchy swelling on the lower lip for the last four months. Careful history and examination revealed a swelling of the lower lip which had gradually increased in size but was static for the last three months. As the patient complained of cosmetic and social inconvenience, it was surgically managed. Any post-operative complications were ruled out and the patient was sent home in a good condition. Much research is warranted to know the exact etiopathogenesis and appropriate management of pleomorphic adenoma of the lower lip.

doi: https://doi.org/10.12669/pjms.39.6.7191

How to cite this: Akram MU, Hasham N, Atique H, Raza A. Pleomorphic adenomia of lower lip: A case report. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.7191

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Lamotrigine-associated toxic epidermal necrolysis
Authors: Farooq Omair , Abbas Akifa , Ahmad Muhammad , Manzoor Abu Bakr
Published: September 2023

Toxic Epidermal Necrolysis (TEN) is an uncommon, idiosyncratic, potentially fatal dermatologic emergency affecting skin and mucous membranes. It is characterized clinically by blistering and widespread exfoliation, and pathologically by apoptosis of keratinocytes and epidermal necrosis. Drugs are one of the most common causative agents. The management ranges from nutritional support, care of denuded skin and mucosa to intravenous immunoglobulins (IVIG). The patient being reported developed TEN, secondary to lamotrigine; an anti-epileptic drug also used for bipolar disorder. On admission, lamotrigine was discontinued, he was managed symptomatically and given IVIG for three days. His condition started to improve after the first dose and he got discharged on 6th day of admission.

doi: https://doi.org/10.12669/pjms.39.6.7513

How to cite this: Farooq O, Abbas A, Ahmad M, Manzoor AB. Lamotrigine-associated toxic epidermal necrolysis. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.7513

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Outcomes of Radioactive Iodine (131I) Therapy among Hyperthyroid patients
Authors: Sajjad Ali Khan Muhammad , Hussain Arshad , Ahmad Shahzad , Shah Muhammad Harris
Published: September 2023

Objective: The present study aimed to assess the thyroid outcomes six-months after radioactive Iodine-131 therapy (RIT) among hyperthyroid patients and identify the factors associated with them.

Methods: This retrospective observational study was conducted at the department of Nuclear Medicine and Molecular Imaging, Northwest General Hospital & Research Centre during 2013 to 2019. For the study purpose, the thyroid outcomes of 153 hyperthyroid patients were studied retrospectively for six months after RIT. The data was obtained from the medical records. Patient baseline characteristics, clinical features, laboratory investigations, results of thyroid imaging, and therapeutic investigations were acquired and recorded in a structured questionnaire.

Results: Out of the 153 screened records of hyperthyroid patients, 19.6% became euthyroid, 9.2% remained hyperthyroid, and 25.5% developed hypothyroidism after six months of RIT. The observed remission rate by the end of six months was 80.95%. Three months post-RIT, gender and RAI doses had a significant effect on thyroid function. The frequency of hypothyroidism was higher among those treated with an RAI dose of ≤ 20 mCi (83.0%) than those treated with a higher dose > 20 mCi (17%). Moreover, most patients receiving > 20 mCi radioiodine became euthyroid (64.5%). Similar outcomes were observed after six months of the therapy, except gender was replaced by etiologies of hyperthyroidism (p=0.009).

Conclusion: Radioactive iodine (131-I) therapy is effective for the treatment of hyperthyroidism. However, the appropriate dose is still debatable, as there was a high incidence of hypothyroidism post-therapy.

doi: https://doi.org/10.12669/pjms.39.6.7567

How to cite this: Khan MSA, Hussain A, Ahmad S, Shah MH. Outcomes of Radioactive Iodine (131I) Therapy among Hyperthyroid patients. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.7567

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Hashimoto's disease - the role of factors and diet in the course of the disease
Authors: Gąbka Ilona , Dalmata Weronika , Gendek Karolina , Dąbrowski Jan , Kozłowska Anna , Korzeniowska Anna , Załęska Natalia , Ziółkiewicz Aleksandra
Published: September 2023

Introduction: Hashimoto's disease is an autoimmune disorder that develops as a result of a pathological reaction of the patient's immune system, which consequently destroys the body's own healthy cells and tissues. Genetic, environmental and immunological factors influence its development. The disease may initially be asymptomatic. The exact aetiology of the disease is unknown. The worldwide incidence is approximately 10-12%.

Purpose: This paper aims to present the influence of genetic factors, environmental factors, trace elements, and diet on the development and course of Hashimoto's disease based on the current state of knowledge.

Conclusions: Hashimoto's disease is a multifactorial disease, but the relevance of all factors presented in the development and progression has not yet been confirmed. To date, a special diet for patients has not been created. Further research is needed to better understand the pathogenesis of the disease in order to help patients control HT.

Methods: Data for the article were retrieved using PubMed setting the time descriptors to 2013-2023.
Secondary Teachers' Self-Efficacy in Supporting Student Mental Health Needs
Authors: Watson Kathryn
Published: September 2023

Abstract: Mental health issues are a barrier to learning for many secondary students. Students with mental health issues need to be identified, and teachers, who see students daily, are essential in identifying, referring, and supporting students with mental health needs. There is scant literature on secondary teachers' self-efficacy in supporting secondary students' mental health and many teachers lack training and confidence in supporting secondary students' mental health needs. Therefore, this narrative study employs Albert Bandura's Social Cognitive Theory to gain insight as to how secondary teachers perceive their self-efficacy in supporting students' mental health needs. Key findings indicate teachers need more training and role clarification on their role in supporting secondary mental health. While teachers can play an essential role in supporting student mental health, this responsibility conflicts with teachers' perceptions of their role in the classroom, thus it is necessary for districts to provide training to ensure teachers understand their role in supporting student learning.
Investigating subject-specific writing skills and historical reasoning in historical explanations: a study of 7th- and 8th-grade comprehensive school students in North Rhine-Westphalia, Germany
Authors: Husemann Charlotte
Published: September 2023

The purpose of this study was to examine the writing skills of 7th- and 8th-grade students with a high proportion of migration background in North Rhine-Westphalia, Germany. The study was part of the SchriFT project (2017–20), funded by the Federal Ministry of Education and Research. A writing task was given on the topic:Why can we only make assumptions about many past events?As an answer to the task, the students had to write a historical explanation that took into account the epistemological principles of historical reasoning. The students’ writing was analysed using a category system, and their historical knowledge was assessed through a knowledge test. The results showed that the students possess diverse levels of writing skills, with few producing elaborate explanations, and most struggling with the subject-specific language and reasoning skills. The study also highlights the potential for genre-based writing approaches in history education. The results suggest that many students perceive history as an image of the past and have limited understanding of historical reasoning. Further research is needed to investigate the influence of motivation and interest on language learning.
Educational reforms and teaching of history in contemporary Spain – nation, history and education as contested issue
Authors: Delgado Ander
Published: September 2023

This article analyses the changes in education legislation and the history curriculum in Spain over recent decades. To this end, the characteristics established for the teaching of history in the last two education laws, passed in 2013 and 2020 – the first by a conservative government and the second by a progressive one – are studied and compared. This study is carried out by situating the education debates presented in this research in the social and political context of Spain. The study of these legislative changes allows us to observe the different visions of national identity existing in Spain, which find a prominent area of confrontation in education and the teaching of history. The article also argues that the emergence of the ultra-right has led to a markedly nationalist vision of Spanish history that seeks to recover elements of national unity, and that has become one of the axes defended by conservative options for the teaching of history in Spanish schools. This view contrasts with the approaches advocated in the latest education legislation, which propose a more heterogeneous approach to the subject of identity in Spain.
Islamic Ethnomethodology Studies to Uncover Local Cultural Values Behind Capital Accounting Practices
Authors: Thalib Mohamad Anwar , Zanna Lizatul , Rauf Fatma , Rasyid Susanti
Published: September 2023

Purpose: The purpose of this study is to find the value of local wisdom behind the business capital of food stalls in Gorontalo.
Methodology : the type of method used is qualitative. there are five stages of data analysis namely charity, knowledge of faith, revelation information, and courtesy.
Findings: The informants obtained capital sourced from debt through their relatives, so there was no guarantee, interest, and flexible terms of debt repayment. Meanwhile, informants who used capital sourced from personal funds were because places to eat, equipment, and business equipment were inherited from their parents. So that informants only need to spend a small amount of money on starting a business. The capital practiced by the owners of the food stalls is conditional on non-material values ​​in the form of kinship. In the culture of the people of Gorontalo, the value of kinship is one of the spirits that the elders often internalize through the expression "dilla bo ilaato binthe wawu pale" This expression means a family statement because of blood relations or is still allied.
Novelty: The novelty of this research is to present capital accounting practices based on local cultural values
Die Bedeutung der Nachhaltigkeitsorientierung bei Gründer/innen
Authors: Gorynia-Pfeffer Natalia , Wallisch Matthias
Published: September 2023

Der „Global Entrepreneurship Monitor“ ist weltweit die einzige Datenquelle, die einen räumlichen und zeitlichen Vergleich der Gründungsquoten vieler Länder in allen Kontinenten ermöglicht. Darin wird auch ein Blick auf die Gründungsmotive von Frauen und Männern in Deutschland möglich. Welche Rolle spielen dabei Perspektiven der Nachhaltigkeit?
Prüfpflichten in der Corporate Sustainability Reporting Directive
Authors: Rössel Hannes , Lodigiani Mario , Ebinger Frank
Published: September 2023

Mit der Einführung der Corporate Sustainability Reporting Directive werden Prüfpflichten zu den im Lagebericht publizierten Nachhaltigkeitsinformationen eingeführt. Der vorliegende Beitrag widmet sich den Fragen, was geprüft wird, wer prüft und wie geprüft wird. Abschließend wird kurz die nationale Umsetzung der Prüfpflichten ins deutsche Recht angesprochen.
Klima- und Biodiversitätsschutz erfordern eine Postwachstumsökonomie
Authors: Dehnhardt Alexandra , Petschow Ulrich
Published: September 2023

Gesellschaft und Wirtschaft sind eingebettet in die Natur. Zur Einhaltung der planetaren Grenzen sind jedoch Dimensionen der Entkopplung erforderlich, die nicht erreichbar sind. Welche Bedeutung hat die daraus abgeleitete Postwachstumsgesellschaft für den Schutz von Klima und Biodiversität?
Nachhaltigkeitspotenziale von digitaler GreenTech erkennen und nutzen
Authors: Möller Martin , Becker Nikolas , Köhler Andreas , Schwarz Linda
Published: September 2023

Digitale Technologien bergen beträchtliche Potenziale für Nachhaltigkeitsgewinne, zum Beispiel bei einer Anwendung in Forst-, Kreislaufund Wasserwirtschaft. Andererseits kann ihre Herstellung und Nutzung einen erheblichen Rohstoff- und Energiebedarf verursachen. Führt die Digitalisierung dennoch zu einer gesamthaften Entlastung? Wie kann dies frühzeitig im Entwicklungsprozess erkannt und bestmöglich genutzt werden?
Quantification of cardiac pumping mechanics in TAVI patients: A pilot study utilizing minimally invasive method for pressure‐volume analysis
Authors: Ko Tsung‐Yu , Chuang Chia‐Chuan , Lin Mao‐Shin , Chen Yi‐Chang , Chen Ying‐Hsien , Huang Ching‐Chang , Yeh Chih‐Fan , Wang Ming‐Jiuh , Chang Kuo‐Chu , Ho Yi‐Lwun , Kao Hsien‐Li
Published: September 2023

The ventriculo‐arterial coupling (VAC) and left ventricle (LV) mechanics are crucial and play an important role in the pathophysiology of aortic stenosis (AS). The pressure‐volume (PV) analysis is a powerful tool to study VAC and LV mechanics. We proposed a novel minimally‐invasive method for PV analysis in patients with severe AS receiving transcatheter aortic valve implantation (TAVI). Patients with severe AS were prospectively enrolled in a single center. LV pressure and cardiac output were recorded before and after TAVI. We constructed the PV loop for analysis by analyzing LV pressure and the assumed flow. 26 patients were included for final analysis. The effective arterial elastance (Ea) decreased after TAVI (3.7 ± 1.3 vs. 2.9 ± 1.1 mmHg/mL, p < 0.0001). The LV end‐systolic elastance (Ees) did not change immediately after TAVI (2.4 ± 1.3 vs. 2.6 ± 1.1 mmHg/mL, p = 0.3670). The Ea/Ees improved after TAVI (1.8 ± 0.8 vs. 1.2 ± 0.4, p < 0.0001), demonstrating an immediate improvement of VAC. The stroke work (SW) did not change (7669.6 ± 1913.8 vs. 7626.2 ± 2546.9, p = 0.9330), but the pressure‐volume area (PVA) decreased (14469.0 ± 4974.1 vs. 12177.4 ± 4499.9, p = 0.0374) after TAVI. The SW/PVA increased after TAVI (0.55 ± 0.12 vs. 0.63 ± 0.08, p < 0.0001) representing an improvement of LV efficiency. We proposed a novel minimally invasive method for PV analysis in patients with severe AS receiving TAVI. The VAC and LV efficiency improved immediately after TAVI.
THERMAL AND ELECTROPHYSICAL PROPERTIES OF PCTFE-TEG AND PCTFE-TEG/SIO2 NANOCOMPOSITES
Authors:   Dragomanov Ukrainian State University, 9 Pyrohova str., Kyiv, 01601, Ukraine, Sichkar Taras , Rokytskyi Maksym ,   Dragomanov Ukrainian State University, 9 Pyrohova str., Kyiv, 01601, Ukraine, Demchenko Valery ,   Institute of Macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02155, Ukraine, Shut Andrii ,   National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, 37 Peremohy prosp., Kyiv, 03056, Ukraine
Published: September 2023

Methods for dispersing of the thermally expanded graphite (TEG) in a dilute alcohol medium and for modifying the surface of a TEG with an ultradisperse dielectric - silicon dioxide (SiO2) are proposed. The new polymer nanocomposites (PNC) obtained based on polychlortrifluoroethylene (PCTFE) with a low content of dispersed TEG and a modified filler TEG/SiO2 are characterized by high rates of electrophysical properties. Using electron microscopy and X-ray photoelectron spectroscopy, the features of the electronic structure of the surface of composites are investigated. Using the two-contact method in the kilohertz frequency range, the features of change in the electrophysical properties of composites depending on the content of fillers and temperature have been established. Based on research and comparative analysis of thermophysical properties (specific heat capacity cp, temperature coefficient of linear expansion α) of the systems, the influence of the structural-morphological state of the components and their concentration, the level of interfacial interaction on the physical properties of nanocomposites was investigated. The fact of the appearance of interfacial polarization in the PCTFE-TEG/SiO2 interfacial layers due to the appearance of the TEG/SiO2 and PCTFE-SiO2 interphase layers is established, which, while preserving the complex of properties inherent to the polymer materials, increases the overall electrical conductivity of the composites. It was also established that the modified nanofiller exhibits greater activity in relation to the polymer matrix than the unmodified one. It is shown that the composites exhibit a dual effect of the modified nanofiller on the matrix structure, which manifests in the formation of a powerful crystalline structure in the zones of influence of the nanofiller and amorphization of the polymer matrix in the peripheral zones. It was found that the result of amorphization of the matrix is a decrease in the area of the peaks of temperature reflexes on the temperature dependences of the specific heat capacity and an increase in the absolute value of the temperature coefficient of linear expansion with an increase in the concentration of modified TEG.
Queering Gender, Race, Embodiment
Authors: Albrecht Jessica
Published: September 2023

The Essay presents provocative peer-reviewed scholarship that examines the field-wide implications of the latest research queries in Religious Studies. In this edition, Jessica Albrecht, a doctoral student at the University of Heidelberg, stresses the need for scholars to consider the role of the body within the critical study of religion. Albrecht argues that greater attention to material and corporeal relations is necessary for Religious Studies to advance its intellectual and pedagogical goals, goals that in the 21st century are presumably interested in decolonization. The Bulletin is pleased to publish this expanded version of this article, of which the original appeared in the German publication “Geschlecht, Sexualität, Verkörperung verqueert: Ansätze und Leitfragen in religionswissenschaftlicher Forschung und Lehre,” Handbuch der Religionen (forthcoming).
Teaching and Learning with Dr. Chris Jones
Authors: Newton Richard
Published: September 2023

The Interview connects Bulletin readers with scholars who have been shaping key aspects of our work in the field. Chris Jones of Washburn University in Topeka, KS takes some time to chat with us. Many of you will know his work on Twitter and other social media platforms where he shares what he’s learning and teaching in the classroom. Jones is no stranger to the shifting currents facing the education of scholars and students in the academic study of religion, so we are most pleased he could join us to discuss these and other matters.
What is the GCPR?
Authors: Loewen Nathan , Knepper Tim , Kopf Gereon
Published: September 2023

The Conversation puts an ear to current discussion in the field. With scholars reevaluating the legacy of every facet of Religious Studies, the team at the Bulletin thought to check in with what is happening in the world of philosophy. In so doing, we learned about an exciting endeavor known as Global Critical Philosophy of Religion. Philosophers Nathan Loewen University of Alabama), Tim Knepper (Drake University), and Gereon Kopf (Luther College) were kind enough to answer our questions about GCPR.
AVALIAÇÃO FORMATIVA NOS GRUPOS TUTORIAIS: UMA ANÁLISE COM BASE NA IDONEIDADE DIDÁTICA EMOCIONAL
Authors: Vasconcelos Pedro Fonseca de , Gusmão Tânia Cristina Rocha Silva , Duarte Ana Cristina Santos
Published: September 2023

A avaliação formativa consiste em uma verificação qualitativa das habilidades e competências de um indivíduo em processo instrucional formal. Essa avaliação constitui-se como fundamental para o andamento dos grupos tutoriais, presentes na metodologia da Aprendizagem Baseada em Problemas, utilizada amplamente nos cursos de Medicina do Brasil. Porém, fatores como a falta de conhecimento e medo do processo avaliativo impedem que ela seja efetivada. Portanto, esse estudo visa analisar como ocorre a avaliação formativa em grupos tutoriais, com base na Idoneidade Didática Emocional. Ou seja, pretende compreender como a avaliação formativa afeta o interesse, a atitude e as emoções dos alunos que participam do grupo tutorial. A pesquisa caracteriza-se como qualitativa, tendo como informantes alunos e uma tutora do curso de Medicina de uma faculdade do interior da Bahia. Para coleta de dados foi utilizada a Observação Participante com utilização de questionários estruturados e observação da dinâmica tutorial no ano de 2021. A análise dos dados se deu através do Critério de Idoneidade Didática Emocional adaptados para o curso de Medicina, que tem a finalidade de medir como discentes se interessam e são afetados no processo ensino-aprendizagem. Como resultado percebeu-se que os discentes e docente ainda valorizam mais a avaliação somativa em detrimento à formativa, criando comportamentos aversivos ao processo avaliativo, tais como ansiedade e medo. Percebeu-se a noção da importância da avaliação ao final da tutoria como forma de estimular o desenvolvimento de habilidades e atitudes, embora ela não siga uma padronização de autoavaliação, avaliação dos pares, avaliação do tutor e avaliação pelo tutor.
Anne Baba Tutumları ve Karar Verme Stilleri İlişkisinde Öğrenilmiş Güçlülüğün Aracı Rolü: Bir Karma Yöntem Araştırması
Authors: MUTLU Şahabettin , KAYA Zöhre
Published: September 2023

: Bu araştırmada, üniversite öğrencilerinin algıladıkları anne baba tutumları, karar verme stilleri ve öğrenilmiş güçlülük düzeyleri arasındaki ilişkilerin incelenmesi amaçlanmıştır. Karma yöntem araştırma modellerinden açımlayıcı sıralı desene göre gerçekleştirilen bu çalışmanın nicel verileri, Anne Baba Tutum Ölçeği, Melbourne Karar Verme Stilleri Ölçeği ve Rosenbaum Öğrenilmiş Güçlülük Ölçeği aracılığıyla toplanmıştır. Araştırmanın nitel verileri ise araştırmacı tarafından hazırlanan Yarı Yapılandırılmış Görüşme Formu ile elde edilmiştir. Çalışmanın nicel verileri seçkisiz olmayan örnekleme yöntemlerinden uygun örnekleme yolu ile 534 üniversite öğrencisinden, nitel verileri de bu öğrenciler arasından amaçlı örnekleme yöntemlerinden ölçüt örnekleme ile seçilen 12 öğrenciden toplanmıştır. Nicel verilerin analizinde, betimsel analiz, açımlayıcı ve doğrulayıcı faktör analizleri, korelasyon analizi, güvenirlik analizi ve SPSS tabanlı PROCESS makro analizi kullanılmış, nitel verilerin analizinde ise içerik analizi kullanılmıştır. Elde edilen nicel bulgulara göre değişkenler arasında kısmen anlamlı ilişkiler olduğu ve anne baba tutumlarının hem doğrudan hem de öğrenilmiş güçlülük aracılığı ile karar verme özsaygısı ile karar verme stillerini yordadığı belirlenmiştir. Araştırmanın nitel bulguları, öğrencilerin karar verirken gerçekçi, mantıklı, anlık, kararsız ve bağımlı gibi yollar izledikleri ve bu yolların şekillenmesinde ise çocukluk deneyimleri, kişilik özellikleri, diğer insanların düşünceleri ve başkalarının deneyimlerinin etkili olduğunu ortaya koymuştur. Ayrıca katılımcıların karar vermede izledikleri yolların; plansızlık, pişmanlık ve tatminsizlik gibi yaşamlarını etkileyen hatalı bazı sonuçlar ortaya koyduğu belirlenmiştir. Araştırma neticesinde nitel bulguların, nicel bulgular ile paralellik gösterdiği ve nicel bulguları anlamlı hale getirdiği sonucuna ulaşılmıştır.
Ergenler için Dijital Bağımlılık Ölçeği: Türkçeye Uyarlama, Geçerlik ve Güvenirlik Çalışması
Authors: BAĞATARHAN Tuba
Published: September 2023

Bu araştırmanın amacı Seema, Heidmets, Konstabel ve Varik-Maasik (2022) tarafından geliştirilen Ergenler için Dijital Bağımlılık Ölçeği’ni Türkçeye uyarlayarak geçerlik ve güvenirlik çalışmalarını gerçekleştirmektir. Araştırma Aydın ili Efeler ilçesinde basit tesadüfi örnekleme yöntemi ile seçilen üç ortaokul ve üç lisede eğitim gören 611 öğrencinin katılımıyla gerçekleştirilmiştir. Araştırmada Ergenler için Dijital Bağımlılık Ölçeği, Young İnternet Bağımlılığı Testi-Kısa Formu, Akıllı Telefon Bağımlılığı Ölçeği-Kısa Versiyonu, Yaşam Doyumu Ölçeği ve kişisel bilgi formu kullanılmıştır. Ölçeğin yapı geçerliğini incelemek için doğrulayıcı faktör analizi yapılmış ve Ergenler İçin Dijital Bağımlılık Ölçeği’nin tek faktörlü yapısı doğrulanmıştır. Ergenler için Dijital Bağımlılık Ölçeği’nin ölçme modelinin cinsiyete göre ölçme değişmezliğini sağladığı belirlenmiştir. Ergenler için Dijital Bağımlılık Ölçeği ile Young İnternet Bağımlılığı Testi-Kısa Formu ve Akıllı Telefon Bağımlılığı Ölçeği-Kısa Versiyonu arasında pozitif yönlü anlamlı ilişkiler tespit edilerek benzer ölçek geçerliğinin sağlandığı görülmüştür. Ayrıca, Ergenler için Dijital Bağımlılık Ölçeği ile Yaşam Doyumu Ölçeği arasında negatif yönlü anlamlı bir ilişki tespit edilerek ayırt edici ölçek geçerliğinin sağlandığı belirlenmiştir. Güvenirlik çalışmaları kapsamında yapılan iç tutarlılık analizi sonucunda Ergenler için Dijital Bağımlılık Ölçeği’nin Cronbach alfa güvenirlik katsayısı 0,87 bulunmuştur. Ölçeğin test-tekrar test güvenirlik katsayısı ise 0,83 olarak hesaplanmıştır. Araştırma bulguları Ergenler için Dijital Bağımlılık Ölçeği’nin Türkçe versiyonunun geçerli ve güvenilir bir ölçme aracı olduğunu göstermektedir.
Gordon Matta-Clark: de la Idea como Modelo al Ejemplo como Práctica
Authors: Salas Lamamié de Clairac Ramón
Published: September 2023

Gordon Matta Clark, uno de los artistas visuales más influyentes del siglo pasado, era arquitecto. No obstante, desde el mismo momento de su graduación manifestó claras discrepancias con sus colegas. Su legendaria “participación” en la exposición Idea as model ilustra a la perfección no solo el espíritu radicalmente renovador del arte de la década de los 70 sino el tránsito del paradigma modernista al posmoderno. A partir de la deconstrucción del título de aquella muestra en el IAUS, este artículo analiza las múltiples y variadas estrategias de la obra de Matta Clark para horadar la epidermis arquitectónica como ejemplo de la evolución estética desde el idealismo autónomo y el ensimismamiento disciplinar hacia el arte contextual y transdisciplinar. Matta-Clark, menos preocupado por tener ideas que por dar ejemplo, parece entender el posmodernismo desde un punto de vista muy alejado de Scott Brown, Venturi o Moore, pero también de Judd o Serra. Su obra interpreta la crisis del modernismo y la especificidad para el lugar como una exhortación a la arquitectura –y al arte en general– a adquirir una mayor sensibilidad hacia los procesos de transformación social y urbana que se estaban viviendo en el tránsito del fordismo al posfordismo.
Revolutionizing the Industrialization of Buildings with BIM and AI: Factors Influencing Adoption and Development and Building Planning
Authors: Yang Hongjuan , Wang Ningning , Zheng Yadi
Published: September 2023

The continuous development of BIM and AI has made the analysis of building industrialization a hot spot in research and made the issue of industrial reform the focus of computer and construction research. The traditional architectural planning method cannot solve the problem of building industrialization reform under AI technology, and the accuracy of architectural planning is low. Therefore, this paper proposes a model based on BIM and AI technology to analyze the development mode and planning of building reform. First, BIM and AI technology are used to analyze the building data, and the irrelevant construction industrialization data is deleted according to the development mode and planning of the data characteristics. Then, according to the judgment results of construction data, compared with the traditional architectural planning method, the content of different construction industries is deeply excavated, and the influencing factors with higher possibilities are output. After simulation test and analysis, BIM and AI technology can improve the judgment accuracy, integrity, and rationality of the influencing factors of building industrialization planning, with an accuracy rate of 96.4%, and make the correct choice of development mode to meet the judgment needs of influencing factors of architectural planning.
Morphometric scale of readiness of the limb stump for prosthetics and assessment of the technical condition of the operated prosthesis
Authors: Osmonaliev Ikar Zh. , Bilgildeev Murat G. , Ergashev Khalimjon Kh. , Abdurakhmanov Rakhmonzhon V. , Baikeev Rustem F.
Published: September 2023

BACKGROUND: There are currently no quantitative criteria for the completion of the upper and/or lower limb stump after amputation or disarticulation for prosthetics, even though this is a key moment at the start of a patient's stage of medical rehabilitation and social adaptation. Also, there is no scale for assessing the technical condition of a prosthetic limb that is already in use.
OBJECTIVE: To develop evaluation scales to assess the morphometric stump readiness for prosthetics and the technical condition of the prosthesis in use.
MATERIALS AND METHODS: The current standards and Interstate Standard concerning the issues of prosthetics after limb amputation in the Russian Federation and in the world, as well as medical documentation containing information recorded during limb amputation or disarticulation were analyzed.
RESULTS: The developed scales for stump condition assessment and technical condition of a prosthesis in use will allow to determine the final criteria of stump readiness for prosthetics and timely eliminate technical prosthesis defects or replace it, thus maintaining the patient's social activity without forced interruptions.
CONCLUSION: In this study we significantly expanded the assessment scale of the limb stump morphometric readiness and detailing for prosthetics and the technical condition of the prosthesis in use in comparison with the existing Interstate Standard; quantitative criteria were introduced, allowing the traumatologist to have a clear algorithm of actions both when treating patients immediately after limb amputation (disarticulation) and in terms of assessing the condition of the prosthesis in use; scales suitable for implementation in medical electronic document management have been developed.
The use of an individual acetabular component for acetabular defect: a clinical case
Authors: Aleksanyan Hovakim A. , Chragyan Hamlet A. , Kagramanov Sergey V. , Khanmuradov Ruslan A. , Zagorodniy Nikolay V.
Published: September 2023

BACKGROUND: The incidence of total hip replacements is increasing every year. Acetabular defects are becoming more frequent, with Paprosky type IIIA and above becoming more common. Recently, customized 3D-printed constructs have been used to remodel severe defects. We wanted to demonstrate the possibility of treating a patient with a severe acetabular defect by performing a one-stage revision endoprosthesis using a customized design.
CLINICAL CASES DESCRIPTION: A 69-year-old patient underwent primary total hip replacement of the right hip joint with a Biomet endoprosthesis for coxarthrosis in 2010. In 2011 on the left side with a Zimmer endoprosthesis. In 2013 revision endoprosthesis of the right hip joint due to instability was preformed. In the postoperative period, there were repeated dislocations with subsequent closed repositioning. In 2015, revision endoprosthetic replacement with a Burkh-Schneider antiprotrusion ring was done for recurrent dislocation. In november 2017, she was diagnosed with instability of the right total hip joint, for which she underwent revision hip replacement with a customized acetabular component.
HHS score before revision arthroplasty was 18 points, 1 month after surgery 75 points, after 3 months 65, after 6 months 82, after 4 years 74. Quality of life was assessed using the WOMAC scale: 92 points before surgery, 38 points 1 month after surgery, 31 points in 3 months, 15 points in 6 months, and 35 points in 4 years. As of the last visit, the patient moves with a cane, and still has a limp due to scar remodeling and gluteal muscles atrophy.
CONCLUSION: In case of severe acetabular defects, the use of individual components allows achieving reliable "implantbone" fixation, which leads to improved functional results. However, in chronic pelvic bone integrity defects, the use of an individual acetabular component does not always achieve reliable stabilization. All existing methods for solving this problem are currently ambiguous and require further improvement.
Pathogenetic and clinical aspects of osteoarthritis and osteoarthritis-associated defects of the cartilage of the knee joint from the standpoint of understanding the role of the subchondral bone
Authors: Kotelnikov Gennadiy P. , Lartsev Yuriy V. , Kudashev Dmitry S. , Zuev-Ratnikov Sergey D. , Asatryan Vardan G. , Shcherbatov Nikita D.
Published: September 2023

The article presents an analytical review on modern ideas about the osteoarthritis pathogenesis based on the findings regarding the subchondral bone and its importance in the development of this disease. It is shown that the data of numerous studies in recent years reveal more and more evidence demonstrating the primacy of pathological changes in the subchondral bone in the development of osteoarthritis and its progression. The vast majority of scientific papers confirm the fact that hyaline cartilage and subchondral bone tissue are a single morphofunctional biocomposite with an interdependent system of biochemical connections and molecular signaling, as well as correlative reactions to stressful mechanical loads. The authors analyzed in detail the mechanisms of cellular and molecular interaction in the system "hyaline cartilage subchondral bone" in the development of osteoarthritis, vividly demonstrating the active and priority involvement of subchondral bone tissue in the debut and maintenance of the destructive-dystrophic process. The necessity to leave the chondrocentric model of osteoarthritis pathogenesis and the expediency to revise the points of application of therapeutic measures in patients with knee joint osteoarthritis are discussed. The current methods of surgical treatment of knee joint osteoarthritis are critically reviewed from the perspective of their pathogenetic orientation. The authors discuss the relevance in developing the concept of organ-preserving surgery in destructive-dystrophic joint lesions, which should be based on the findings describing the role and significance of subchondral and metaphyseal bone tissue in the above pathologic processes.
Evaluation of clinical and functional outcome of total hip arthroplasty in avascular necrosis of head of femur in adults
Authors: Lingayat M. B. , Baria Karan , Muslim Sufyan M. , Chavan Santosh B. , Shaikh Shanshah
Published: September 2023

Background: Aim of the study was to evaluate clinical and functional outcome of bipolar hemiarthroplasty in avascular necrosis (AVN) of HIP in adults.
Methods: Thirty patients of either sex between age group 20-80 years of age came for the treatment at government medical college and hospital Aurangabad. Between December 2020 to December 2022. Patients were followed every day till the discharge. Patients were discharged after they were mobilised with assistance of physiotherapist. Functional and clinical outcome was measured at 6, 12 and 24 weeks postoperatively according to Harris hip score (HHS).
Results: the methods show significant improvement in HHS in patient undergoing total hip replacement.
Conclusions: total hip replacement is a very good option for AVN of head of femur in all age groups.
Exploring clinical effects and usage patterns of a daily face cleanser enriched with glycolic acid, aloe vera, and vitamin-E for acne management: a post-hoc analysis
Authors: Kumari Pradeep , Bhatt Deepa K. , Manoharan K. , Agarwal Praveen , Leelavathy B. , Arya Anurag , Nair Rathish , Korukonda Krishnaprasad
Published: September 2023

Background: Face cleansers are recommended as adjuncts to acne therapy to counteract the acne related manifestation like acne spots and post inflammatory hyperpigmentation (PIH). This complementary study was designed to assess the clinical impact and tolerability of glycolic acid, aloe vera and vitamin-E based face cleanser for daily use in acne patients prescribed with clindamycin, tretinoin, adapalene and benzoyl peroxide for management of acne in real-world scenario.
Methods: We conducted a retrospective review at 193 centres, focusing on individuals having acne with oily and mix skin types who used face cleanser twice a day. Total 619 cases (D age: 28.94±7.92 years) of acne were further analysed over a 4-week study period to study improvement in post-inflammatory hyperpigmentation, acne spot reduction and enhance skin radiance and glow using subjective assessment questionnaires.
Results: The face cleanser, when used regularly with standard of care, significantly reduced acne (43.58%), acne spots (44.85%), and PIH (46.06%) with statistical significance (p<0.01). Patients with oily and mix skin type, 337 (54.44%) and 264 (42.65%) rated improvement on acne spots, PIH, radiance, and glow to be good to excellent, respectively. No patients experienced serious adverse events (AEs) or cleanser-related adverse event.
Conclusions: The facial cleanser demonstrated effectiveness and tolerance in treating acne patients who were prescribed with anti-bacterial and anti-inflammatory agents. In 4-week long treatment period, the facial cleanser enhanced skin radiance and also demonstrated its worth as a beneficial inclusion in everyday skincare regimens.
Factores asociados al desarrollo de secuelas por trauma craneoencefálico en menores de 15 años: un estudio de cohorte retrospectiva en un hospital de Medellín, Colombia. 2010–2014
Authors: Aránzazu-Ceballos Andrés David , Maldonado-Mejía Luis Camilo , Ortiz-Giraldo Blair , Marín-Pineda Diana
Published: September 2023

Introducción: el trauma craneoencefálico es una de las principales causas de morbimortalidad infantil en Colombia, sus secuelas impactan gravemente la calidad de vida de los pacientes y la evidencia científica actual de los factores asociados al trauma es escasa. Objetivo: analizar los factores asociados al desarrollo de secuelas por trauma craneoencefálico en menores de 15 años que consultaron a un hospital de Medellín entre 2010 y 2014. Materiales y métodos: estudio de cohorte retrospectivo. Se incluyeron 812 pacientes en un periodo de 5 años, de los cuales 294 no cumplieron los criterios de inclusión. Se evaluaron variables sociodemográficas, clínicas y se estimó la incidencia de secuelas con el método estadístico de Wilson. El riesgo relativo se calculó mediante regresión log-binomial. Resultados: en total se analizaron 518 pacientes. La mediana de edad fue de 5 años, el 64,3 % eran hombres, el 75,4 % de los participantes tenía un trauma leve y el 5 % un trauma grave. Las caídas fueron la principal causa (64,2 %), seguidas de los accidentes de tránsito (25,3 %). La incidencia de secuelas fue del 7.3 % (IC: 5,4 % – 9,9 %). Conclusiones: la carga de enfermedad en el paciente posterior a TCE representa un problema de salud pública. La probabilidad de desarrollar una secuela en este estudio fue del 7,3 %, la cual se relaciona con los siguientes factores que se identifican en el servicio de urgencias: lesión difusa, una escala de Glasgow al ingreso moderada o grave y sufrir un accidente de tránsito.
Caracterización de estilos de aprendizaje, satisfacción y acceso a residencia médica en participantes de un programa de educación médica continuada bimodal/virtual en Medellín, Colombia, 2017
Authors: Patiño-Girado Santiago , Gaviria Juan José
Published: September 2023

Introducción: los estilos de aprendizaje son rasgos del estudiante que pueden ayudar a la planificación curricular en educación médica. No se conoce con certeza si algún estilo de aprendizaje específico se relaciona con la satisfacción en educación médica continuada o si aumenta las probabilidades de acceder a una residencia médica. Objetivo: este trabajo buscó categorizar los estilos de aprendizaje en una cohorte de médicos, describir su satisfacción según cada estilo de aprendizaje y el acceso a una residencia médica. Materiales y métodos: estudio de corte transversal en médicos cursando un diplomado de actualización médica. Se categorizaron estilos de aprendizaje y sus combinaciones (activo, reflexivo, teórico y pragmático). Se calculó la diferencia de medias de satisfacción del curso. Posteriormente, se evaluó la asociación entre el estilo de aprendizaje y el acceso a un cupo de residencia médica. Resultados: trescientos once médicos (n=311) aceptaron participar. El 75 % tenían entre uno y dos estilos dominantes, siendo el más frecuente el reflexivo/teórico (n=108; 34,7 %). No se encontró una mayor satisfacción global asociada a un estilo en particular. Conclusión: el estilo de aprendizaje dominante es el reflexivo/teórico. La satisfacción global es mayor en la modalidad bimodal. No se encontró asociación con ningún estilo de aprendizaje y el acceso a residencia médica.
La enfermera de enlace: revisión de su actuación en la continuidad del cuidado
Authors: Gómez-Torres Danelia , Gómez-Alcántara Karla Sofía
Published: September 2023

Introducción: la enfermera de enlace no es de aparición reciente, sus funciones se han diversificado posicionándose como una profesionista importante en el proceso de alta hospitalaria, el objetivo de la revisión es identificar la actuación de la enfermera de enlace en la continuidad del cuidado a los pacientes tras su alta hospitalaria. Materiales y métodos: revisión integradora realizada en cuatro bases de datos, con publicaciones entre 2010 y 2020, siendo seleccionadas 12 investigaciones. Para la búsqueda se utilizaron los descriptores: alta del paciente, continuidad de la atención al paciente, cuidado de transición, gestores de casos, perfil laboral y práctica profesional. Resultados: la enfermera de enlace actúa hacia la planificación del alta hospitalaria, gestión de recursos y vínculo del sistema de salud. Conclusiones: las enfermeras de enlace actúan hacia un modelo de cuidados centrados en el paciente, evitando el cuidado fragmentado, mejorando el flujo de información entre niveles asistenciales, propiciando continuidad.
A Lack of Joi: Hegemonic Femininity and the Male Gaze in Blade Runner: 2049
Authors: McCann Ashley , Engstrom Erika
Published: September 2023

This article examines how the 2017 film Blade Runner: 2049 reinforces a patriarchal viewpoint utilizing hegemonic femininity and the male gaze as theoretical approaches. The holographic character Joi's appearance and interactions with the male protagonist K reflects hegemonic femininity, which adds to how the film's women characters reaffirm the centrality of K and gender stereotypes that prevent this sequel from reflecting any expected progress since the release of the original Blade Runner in 1982.
Black Parallax: Hollywood's Recent Approach to Mitigating Racial Excess
Authors: Cosey Felicia
Published: September 2023

This paper argues that from 2013 to 2021 Hollywood filmmakers have favored casting Black British actors to play Black American characters in dramas dealing with racism and oppression in the US in order to remove the racial excess associated with Black American subjects. Once excess is removed, filmmakers feel free to craft narratives that appeal to US moviegoers and that elide the national shame of the enslavement and persecution of descendants of American slaves.