bluuebunny/crossref_metadata_2025 huggingface dataset:
Lead contamination in human milk affects infants’ language trajectory: results from a prospective cohort study
Authors: Naspolini Nathalia Ferrazzo , Vanzele Pedro A. R. , Tótolo Pedro , Schüroff Paulo Alfonso , Fatori Daniel , Vicentini Neto Santos Alves , Barata-Silva Cristiane , dos Santos Lisia Maria Gobbo , Fujita André , Passos-Bueno Maria Rita , Beltrão-Braga Patricia C. B. , Campos Alline C. , Carvalho André C. P. L. F. , Polanczyk Guilherme V. , Moreira Josino Costa , Taddei Carla R.
Published: August 2024

Infants growing up in low- and middle-income countries are at increased risk of suffering adverse childhood experiences, including exposure to environmental pollution and lack of cognitive stimulation. In this study, we aimed to examine the levels of metals in the human milk of women living in São Paulo City, Brazil, and determine the effects on infants’ neurodevelopment. For such, a total of 185 human milk samples were analyzed for arsenic (As), lead (Pb), mercury (Hg), and cadmium (Cd) using inductively coupled plasma mass spectrometry (ICP-MS). We applied the Bayley scales of infant and toddler development Third Edition (Bayley-III) to assess developmental milestones. In our analysis, we found a mean (standard deviation) concentration of As in human milk equal to 2.76 (4.09) μg L−1, followed by Pb 2.09 (5.36) and Hg 1.96 (6.68). Cd was not detected. We observed that infants exposed to Pb presented language trajectories lower than non-exposed infants (β = −0.413; 95% CI -0.653, −0.173) after adjustment for infant age, maternal education, socioeconomic status, infant sex, and sample weights. Our results report As, Pb, and Hg contamination in human milk, and that infant exposure to Pb decreased infants’ language development. These results evidence maternal-child environmental exposure and its detrimental impact on infants’ health.
High school students' social media use predicts school engagement and burnout: the moderating role of social media self-control
Authors: Du Jie , Wang Yu
Published: August 2024

Students' social media use has quickly gained attention given the effect of considerable time spent on and widespread usage of social media on their development and success. The study aimed to examine whether high school students' social media use predicts more school engagement and less burnout for those who were more successful in controlling their social media use in goal-conflict situations. A sample of 107 Chinese high school students (Mage = 19.21, SDage = 1.85, 68% female) participated in an online survey. The results showed that social media self-control failure moderated the relationship between general social media use (rather than social media use intensity) and school engagement. A simple effect test revealed that more general social media use predicted higher school engagement for students who were more successful in controlling their social media use. However, no moderation effect was observed of social media self-control failure on the relationship between social media use intensity (or general social media use) and burnout. The results partially supported the study demands-resources model and indicated the potential benefits of controllable social media use on high school students’ engagement in the face of high academic demands.
Concepts for drone based pipeline leak detection
Authors: Bretschneider Lutz , Bollmann Sven , Houssin-Agbomson Deborah , Shaw Jacob , Howes Neil , Nguyen Linh , Robinson Rod , Helmore Jon , Lichtenstern Michael , Nwaboh Javis , Pogany Andrea , Ebert Volker , Lampert Astrid
Published: August 2024

The quickly developing drone technology can be used efficiently in the field of pipeline leak detection. The aim of this article is to provide drone mission concepts for detecting releases from pipelines. It provides an overview of the current applications of natural gas pipeline surveys, it considers environmental conditions by plume modelling, it discusses suitable commercially available sensors, and develops concepts for routine monitoring of pipelines and short term missions for localising and identifying a known leakage. Suitable platforms depend on the particular mission and requirements concerning sensors and legislation. As an illustration, a feasibility study during a release experiment is introduced. The main challenge of this study was the variability of wind direction on a time scale of minutes, which produces considerable differences to the plume simulations. Nevertheless, the leakage rates derived from the observations are in the same order of magnitude as the emission rates. Finally the results from the modeling, the release experiment and possible drone scenarios are combined and requirements for future application derived.
Relationship between sleep quality and quantity and lower-body neuromuscular performance characteristics in semi-professional male basketball players
Authors: Cabarkapa Damjana V. , Cabarkapa Dimitrije , Fry Andrew C.
Published: August 2024

Sleep has been recognized as one of the most essential recovery methods necessary for achieving optimal performance. However, there is still a lack of scientific literature focused on examining its impact on one of the most prevalent skills in the game of basketball, the countermovement vertical jump (CVJ). Therefore, the purpose of the present study was to examine the relationship between sleep quality and quantity, and lower-body neuromuscular performance characteristics within a cohort of semi-professional male basketball players. Twenty-eight athletes competing in a first-tier regional league in Serbia volunteered to participate in this investigation. Upon arrival at the gym, all athletes completed the Pittsburgh Sleep Quality Index (PSQI) self-rated questionnaire. Immediately after completion of the PSQI, each athlete stepped on a force plate system and performed three maximum-effort CVJs with no arm swing. The following force-time metrics were obtained for the analysis: eccentric and concentric absolute and relative mean and peak force and power, vertical jump height, and reactive strength index-modified. Pearson product-moment correlation coefficients were used to examine the strength of the linear relationships between sleep quality and quantity and lower-body neuromuscular performance characteristics (p < 0.05). The results indicated that sleep quality appears to have a greater impact on the concentric than the eccentric phase of the CVJ (e.g., concentric mean force [r = −0.830; p < 0.001], relative concentric peak force [r = −0.466; p = 0.013, eccentric mean power (r = −0.162; p = 0.409)], while no significant relationship was found between sleep quantity and lower-body neuromuscular performance (e.g., concentric peak force [r = −0.055; p = 0.782], relative eccentric mean power [r = −0.301; p = 0.107]). Overall, these findings offer valuable insights into the importance of good sleep hygiene (e.g., efficiency, duration) in an athletic population, and can help practitioners develop more effective training and recovery programs.
Land, cows, and bullets: an untold history of cattle ranching during the armed conflict in Colombia, 1980–2010
Authors: Triana Ángel Natalia , Burkart Stefan , Pazos Cárdenas Mateo
Published: August 2024

This article reflects on the history of cattle ranching in Colombia and how it was impacted by the armed conflict in the country and its regions, and the transformation amongst decades of forms of violence and actors involved in this scenario. To conduct the analysis, a review of academic literature on the relationship between cattle ranching and armed conflict in Colombia and some African countries was carried out. Subsequently, a database of 206 violent events related to cattle ranching was constructed, covering three decades of armed conflict (1980–2010), based on primary sources from reports, police evidence, and testimonies of two previous databases. This database contributed to the analysis of the impact of violence on the cattle ranching industry. Thus, this article contributes to the understanding of the history of cattle ranching in Colombia and to the complex transitional process in Colombia today. It demonstrates that productivity and efficiency have not always been the prevailing principles in the history of the cattle industry, but that land tenure and accumulation have operated as a way of securing power by the agrarian and political elites of the country. Such approaches are crucial for comprehending the historical connection between conflict and cattle ranching, especially if the aim for this sector is to adapt to a logic of productivity and innovation in the contemporary world. Also, the findings show that further research on these topics, i.e., related to current environmental and social problems such as climate change, food security, and new social and geopolitical challenges, is needed.
Effects of different drying techniques on sea buckthorn pomace: comprehensive assessment of drying characteristics, physicochemical properties, and odor
Authors: Zhou Xiang , Zhang Xiaoqiang , Liu Xinyu , Ji Xinyu , Zhang Qian , Yang Xuhai
Published: August 2024

This study investigated the effects of hot air drying (HAD), infrared-assisted hot air drying (IR-HAD), vacuum freeze drying (VFD), and pulsed-vacuum drying (PVD) on the drying characteristics, color, microstructure, total phenolic content (TPC), total flavonoid content (TFC), vitamin C (Vc) content, and the odor analysis using electronic nose of sea buckthorn pomace. The results showed that IR-HAD exhibited the highest drying rate and the shortest drying time (250 min). PVD exhibited the highest TPC, TFC, and Vc content while maintaining a color difference ΔE value closest to that of the fresh sample. PVD microstructure exhibited no collapse, fewer pores, and smaller cracks than the IR-HAD and VFD microstructures. Furthermore, the PVD pomace displayed the lowest reactivity to sulfides and ethanol compounds. The comprehensive analysis suggests that PVD holds promise as a drying method for sea buckthorn pomace and provides valuable insights for selecting an appropriate drying method for sea buckthorn pomace.
Flavonoids in mitigating the adverse effects of canine endotoxemia
Authors: Móritz Alma V. , Kovács Hédi , Jerzsele Ákos , Psáder Roland , Farkas Orsolya
Published: August 2024

In dogs, chronic enteropathies, and impaired gut integrity, as well as microbiome imbalances, are a major problem. These conditions may represent a continuous low endotoxin load, which may result in the development of diseases that are attributable to chronic inflammation. Flavonoids are polyphenolic plant compounds with numerous beneficial properties such as antioxidant, anti-inflammatory and antimicrobial effects. For our experiments, we isolated primary white blood cells (peripheral blood mononuclear cells and polymorphonuclear leukocytes) from healthy dogs and induced inflammation and oxidative stress with Escherichia coli and Salmonella enterica serovar Enteritidis lipopolysaccharide (LPS). In parallel, we treated the cell cultures with various flavonoids luteolin, quercetin and grape seed extract oligomeric proanthocyanidins (GSOP) alone and also in combination with LPS treatments. Then, changes in viability, reactive oxygen species (ROS) and tumor necrosis factor alpha (TNF-α) levels were measured in response to treatment with quercetin, luteolin and GSOP at 25 and 50 μg/mL concentrations. We found that ROS levels were significantly lower in groups which were treated by flavonoid and LPS at the same time compared to LPS-treated groups, whereas TNF-α levels were significantly reduced only by luteolin and quercetin treatment. In contrast, treatment with lower concentrations of GSOP caused an increase in TNF-α levels, while higher concentrations caused a significant decrease. These results suggest that the use of quercetin, luteolin and GSOP may be helpful in the management of chronic intestinal diseases in dogs with reduced intestinal barrier integrity or altered microbiome composition, or in the mitigation of chronic inflammatory processes maintained by endotoxemia. Further in vitro and in vivo studies are needed before clinical use.
Investigating the use of machine learning algorithms to support risk-based animal welfare inspections of cattle and pig farms
Authors: Thomann Beat , Kuntzer Thibault , Schüpbach-Regula Gertraud , Rieder Stefan
Published: August 2024

In livestock production, animal-related data are often registered in specialised databases and are usually not interconnected, except for a common identifier. Analysis of combined datasets and the possible inclusion of third-party information can provide a more complete picture or reveal complex relationships. The aim of this study was to develop a risk index to predict farms with an increased likelihood for animal welfare violations, defined as non-compliance during on-farm welfare inspections. A data-driven approach was chosen for this purpose, focusing on the combination of existing Swiss government databases and registers. Individual animal-level data were aggregated at the herd level. Since data collection and availability were best for cattle and pigs, the focus was on these two livestock species. We present machine learning models that can be used as a tool to plan and optimise risk-based on-farm welfare inspections by proposing a consolidated list of priority holdings to be visited. The results of previous on-farm welfare inspections were used to calibrate a binary welfare index, which is the prediction goal. The risk index is based on proxy information, such as the participation in animal welfare programmes with structured housing and outdoor access, herd type and size, or animal movement data. Since transparency of the model is critical both for public acceptance of such a data-driven index and farm control planning, the Random Forest model, for which the decision process can be illustrated, was investigated in depth. Using historical inspection data with an overall low prevalence of violations of approximately 4% for both species, the developed index was able to predict violations with a sensitivity of 81.2 and 79.5% for cattle and pig farms, respectively. The study has shown that combining multiple and heterogeneous data sources improves the quality of the models. Furthermore, privacy-preserving methods are applied to a research environment to explore the available data before restricting the feature space to the most relevant. This study demonstrates that data-driven monitoring of livestock populations is already possible with the existing datasets and the models developed can be a useful tool to plan and conduct risk-based animal welfare inspection.
Bio-Inspired Strategies Are Adaptable to Sensors Manufactured on the Moon
Authors: Ellery Alex
Published: August 2024

Bio-inspired strategies for robotic sensing are essential for in situ manufactured sensors on the Moon. Sensors are one crucial component of robots that should be manufactured from lunar resources to industrialize the Moon at low cost. We are concerned with two classes of sensor: (a) position sensors and derivatives thereof are the most elementary of measurements; and (b) light sensing arrays provide for distance measurement within the visible waveband. Terrestrial approaches to sensor design cannot be accommodated within the severe limitations imposed by the material resources and expected manufacturing competences on the Moon. Displacement and strain sensors may be constructed as potentiometers with aluminium extracted from anorthite. Anorthite is also a source of silica from which quartz may be manufactured. Thus, piezoelectric sensors may be constructed. Silicone plastic (siloxane) is an elastomer that may be derived from lunar volatiles. This offers the prospect for tactile sensing arrays. All components of photomultiplier tubes may be constructed from lunar resources. However, the spatial resolution of photomultiplier tubes is limited so only modest array sizes can be constructed. This requires us to exploit biomimetic strategies: (i) optical flow provides the visual navigation competences of insects implemented through modest circuitry, and (ii) foveated vision trades the visual resolution deficiencies with higher resolution of pan-tilt motors enabled by micro-stepping. Thus, basic sensors may be manufactured from lunar resources. They are elementary components of robotic machines that are crucial for constructing a sustainable lunar infrastructure. Constraints imposed by the Moon may be compensated for using biomimetic strategies which are adaptable to non-Earth environments.
The Impact of Molecular and Genetic Analysis on the Treatment of Patients with Atypical Meningiomas
Authors: Ravnik Janez , Rowbottom Hojka
Published: August 2024

Meningiomas represent approximately 40% of all primary tumors of the central nervous system (CNS) and, based on the latest World Health Organization (WHO) guidelines, are classified into three grades and fifteen subtypes. The optimal treatment comprises gross total tumor resection. The WHO grade and the extent of tumor resection assessed by the Simpson grading system are the most important predictors of recurrence. Atypical meningiomas, a grade 2 meningioma, which represent almost a fifth of all meningiomas, have a recurrence rate of around 50%. Currently, different histopathologic, cytogenetic, and molecular genetic alterations have been associated with different meningioma phenotypes; however, the data are insufficient to enable the development of specific treatment plans. The optimal treatment, in terms of adjuvant radiotherapy and postoperative systemic therapy in atypical meningiomas, remains controversial, with inconclusive evidence in the literature and existing studies. We review the recent literature to identify studies investigating relevant atypical meningioma biomarkers and their clinical application and effects on treatment options.
Improving the Interfacial Bonding Strength of Laser Direct Joining between Dissimilar 304 Stainless Steel and PCCF30 Plastic
Authors: Chen Hansong , Liang Huaizhi , Shen Zongbao , Wang Xiao
Published: August 2024

In response to the issue of weak laser connection strength between 304 stainless steel and the carbon fiber-reinforced polymer PCCF30, this study proposes the addition of a polyethylene terephthalate (PET) intermediate layer between 304 stainless steel and PCCF30, along with surface texture pretreatment of the stainless steel surface, to enhance the joint connection strength. First, three types of surface textures (vertical, wavy, and vertical plus wave) were investigated for their effect on joint quality. Once the optimal texture type was determined, the effect of texture scanning repetition on the surface morphology and groove cross-sectional geometry of 304 stainless steel was examined. The joint strengths achieved by adding intermediate layers and employing different surface texture treatment methods were compared, followed by a comparison of the joint strengths obtained from different pretreatment methods. Finally, the connection mechanism of the joint was analyzed. The results indicated that the maximum joint strength achieved through the vertical and wavy texture design was 4.39 MPa, which is 3.3 times greater than that achieved without reinforcement. Moreover, the maximum joint strength achieved with the addition of a PET intermediate layer and surface texture composite treatment was 11.85 MPa, which is approximately nine times greater than that achieved via direct connection. The inclusion of a PET intermediate layer enhances the fluidity of the molten polymer at the joint, facilitating better filling of the grooves with surface texture. This strengthens the mechanical anchoring effect of the joint and contributes to the improvement in the joint’s connection strength. An XPS analysis revealed that after multiple etchings of the joint interface with an added intermediate layer, the Cr in the stainless steel chemically bonded with the PET, resulting in the formation of Cr–O–C chemical bonds, which is advantageous for enhancing joint quality.
The Riddle of Oedipus
Authors: Chappell Sophie Grace
Published: August 2024

What is the riddle of Oedipus? This paper is an exploration of the philosophy involved in Sophocles’ famous play Oedipus Tyrannus. The play involves a riddler who becomes king, a man who is famously good at understanding what others find obscure, and yet is unable to see it when he is confronted by an obvious set of uncomfortable truths about himself. As well as for Oedipus, the play poses a number of different riddles for us: in particular it is a study of responsibility and shame, and of deliberation and choice. Like any work of art, the play does not tell us what conclusions we should reach; but it does show us some questions that need asking, and indeed some riddles that we face.
Complementarity or Crowding Out: The Effects of Government-Led Philanthropic Development
Authors: Song Yahui , Yan Kegao , Yan Guozhang
Published: August 2024

At present, China regards philanthropy as an important component of social security, social governance, and the third distribution of resources. Structural changes in government expenditure can drive the adjustment of social resources; therefore, it is fundamental to investigate the macroeconomic transmission effect of government expenditure on the development of the philanthropic sector in order to promote the sustainable development of philanthropy and ensure the fairness and justice of social distribution. The results of a regression analysis on provincial panel data from 2007 to 2020 indicated the following: (1) Government expenditure exhibits crowding-out effects on various dimensions of the philanthropic sector. (2) In terms of regional development disparities, government guidance shows crowding-out effects on the development of philanthropy in the eastern and central regions; meanwhile, it demonstrates complementary effects on the dimensions of charitable donations and the number of social organizations in the western region. (3) Furthermore, in terms of the regional distribution of social organizations by industry, government guidance in the eastern region exhibits crowding-out effects on the numbers of social organizations in the fields of science and technology, education, culture, health, and sports; meanwhile, in the western region, it shows complementary effects. Additionally, in the central region, it shows a complementary effect only in the cultural sector, with crowding-out effects in other industries. Therefore, greater flexibility should be granted to the philanthropic sector, in which the construction of hub-type philanthropic organizations and the creation of regional industry cooperation platforms promote the relatively balanced development of philanthropy.
Community Resilience Evaluation and Construction Strategies in the Perspective of Public Health Emergencies: A Case Study of Six Communities in Nanjing
Authors: Zhang Fang , Wang Dengyu , Zhou Xi , Ye Fan
Published: August 2024

The theory of resilience has undergone three stages: engineering, ecological, and evolutionary. It has been developed in various professional fields, focusing on research scales such as urban resilience and community resilience. As the smallest unit of urban composition, the community serves as the principal carrier of numerous emergencies at the grassroots level. Its resilience construction level is somewhat connected to the city’s safe development. However, there is still a lack of a systematic evaluation framework for assessing community resilience, and studies from the perspective of public health safety also lack scientific quantitative results and dynamic analysis. In order to fully understand the connotation of resilient community in the combination of epidemic prevention and control, this study employs literature crawling and high-frequency vocabulary screening to construct a three-level resilience index. Taking into consideration both physical and social factors, a community resilience evaluation system with 4 core indicators, 14 secondary indicators, and 39 tertiary indicators is established by employing the resilience matrix (RM) framework and Analytic Hierarchy Process (AHP). It set up a collection quantification path based on the properties of multivariate data and weighted the indicators using the Delphi method. Taking the typical community in Xuanwu District, Nanjing, as the research sample, the differentiated performance during the COVID-19 pandemic is analyzed, and a systematic evaluation and scoring are conducted. The resilience composition and improvement directions of each sample are interpreted and analyzed to support the formulation of future sustainability strategies as much as possible. The study developed an evaluation approach combining three time periods and four response dimensions to demonstrate a relationship between complex factors and community resilience. The expandable resilience evaluation system offers a wide range of applications and serves as a scientific reference for strengthening community resilience, which is critical for urban sustainability.
Tratamento do Transtorno de Déficit de Atenção e Hiperatividade como fator protetivo para o transtorno por uso de substâncias lícitas e ilícitas: uma revisão sistemática
Authors: Martins Beatriz Costa , Calegari Isadora Bertacco Estrela , Oliveira Paola Valarini , Negreiros Natalia Félix
Published: August 2024

Os transtornos do neurodesenvolvimento formam um conjunto de condições que podem levar a déficits no desenvolvimento e se manifestam em idade pré-escolar, nem sempre diagnosticado nessa fase, o que pode causar dificuldade no desempenho social, acadêmico, pessoal e profissional a longo prazo. Evidências demonstraram que o transtorno de déficit de atenção (TDAH) está relacionado ao transtorno por uso de substâncias (TUS) que pode agravar o prognóstico de indivíduos não tratados na infância e/ou ao longo da vida. Dessa forma, foi verificado por meio de revisão sistemática da literatura, se os pacientes que fizeram o tratamento correto de TDAH apresentaram prevenção para TUS. Foi realizada uma revisão sistemática na qual foram analisados estudos na língua portuguesa e inglesa durante os anos de 2016 a 2023. As bases de dados utilizadas foram, PubMed, Lilacs e MedLine, com os descritores Substance Related Disorders, ADHD, Drugs, Substance Use, Substance Use Disorder e Drug abuse. Foram identificados 10 artigos totalizando 3.000.709 pacientes com TDAH. A ausência de tratamento do TDAH, principalmente ao ser comórbido com o TUS, pode interferir na qualidade de vida do indivíduo. Com o uso metilfenidato observou uma melhora nos sintomas do TDAH e na conduta relacionada ao TUS. O tratamento adequado do TDAH apresenta potencial fator protetivo para a prevenção do TUS. Ademais, são necessárias abordagens individuais e avaliação de medicamentos estimulantes, para benefícios de indivíduos com TDAH, além de reduzir impactos negativos associados ao TUS.
Analysis of the impact of COVID-19 on major depressive disorder in adults: a systematic review
Authors: Santos Arthur Ramos , Oliveira Júlia Vieira Salles de , Medeiros Hellen Cristina Pereira de , Pereira Ronaldo Cascelli Schelb Scalla
Published: August 2024

The COVID-19 pandemic has had a multifaceted impact on people's daily lives and has adversely affected the population's mental health in several aspects. Therefore, the objective of this study is to analyze the impact of COVID-19 on the prevalence of major depressive disorder in adults, aiming to summarize the current literature to provide a broader understanding of the topic in pre- and post-pandemic scenarios. For this purpose, a literature review was conducted between October 2023 and February 2024, based on articles published in health databases. The PRISMA method and the PECO strategy were employed alongside the GRADE methodology to analyze the evidence. The study found that while the prevalence of depressive disorders varied geographically, there was a significant global increase due to the pandemic. After a worldwide peak in diagnoses, incidence rates tend to stabilize; however, it is important to note that some sequelae may persist in more vulnerable individuals or those who have contracted COVID-19. In summary, the adverse effects on mental health following the pandemic were evident, with health system responses influencing how countries addressed this increase, underscoring the importance of prioritizing mental health as a public health issue.
Impacto do sono fragmentado em pacientes com insuficiência cardíaca crônica: mecanismos e intervenções
Authors: Toscano Daniela Bezerra de Menezes , Lima Luiza Dias de Andrade , Queiroz Luiz Eduardo Xavier , Rocha Rafaela Dias , Gonçalves Raphaella Franco Fidelis , Câmara Júlia Pereira , Wanderley Fernando Farias , Rocha Maria Eduarda Amaro Ferreira , Andrade Philipe Fernandes Batista de , Figueiredo Juliana Freire Caetano de , Almeida Ana Laura Santos de , Tavares Yasmin Maria Sátiro Cruz , Oliveira Georgia Nóbrega de , Rodrigues João Gabriel de Araújo , Simão Paula Filgueiras Barbosa , Aguiar Lucas Queiroz de
Published: August 2024

A insuficiência cardíaca (IC) é uma condição crônica grave frequentemente associada a distúrbios do sono, como a Apneia Obstrutiva do Sono (AOS) e Apneia Central do Sono (APS). Considerando que o sono fragmentado pode agravar os sintomas da IC e influenciar negativamente os desfechos cardiovasculares, este estudo objetiva revisar a literatura sobre o impacto do sono fragmentado em pacientes com IC. Para tanto, procede-se à análise de 24 estudos relevantes que investigaram parâmetros clínicos, laboratoriais e de qualidade de vida em pacientes com IC e distúrbios do sono. Desse modo, observa-se que pacientes com sono fragmentado e AOS apresentam piora significativa nos desfechos cardiovasculares, como maior incidência de arritmias, aumento na pressão arterial e progressão da disfunção ventricular. Além disso, esses pacientes têm um risco elevado de eventos cardiovasculares adversos, incluindo hospitalizações por descompensação da IC e mortalidade cardiovascular, o que permite concluir que a fragmentação do sono e distúrbios como a AOS têm um impacto negativo substancial em pacientes com IC. Estes achados destacam a importância de intervenções que visem melhorar a qualidade do sono como parte do manejo integral da IC, com potencial para melhorar os resultados clínicos e a qualidade de vida dos pacientes.
Efetividade do aprepitanto como profilático de náusea e vômito no pós-operatório: revisão sistemática
Authors: Costa Rômulo Carvalho , Figueiredo Neto Newton Vital , Uckonn Karina Bittencourt , Martins Luma Moraes , Lima Maria Clara Sandes de , Araujo Maria Clara Vitorio de , Silva Maria Eduarda Ferreira da , Almeida Pedro Alexandre Leite de
Published: August 2024

Náusea e vômito pós-operatório (NVPO) são ocorrências frequentes, podendo atingir 80% dos pacientes que possuem fatores de risco como sexo feminino, idade e uso de opioide após a cirurgia. Nesse sentido, o aprepitanto, antagonista dos receptores da neurocinina 1 (NK-1), possui meia vida de até 12 horas e chamou atenção como antiemético para NVPO. Esta pesquisa avaliará a efetividade profilática do aprepitanto na NVPO. Trata-se de uma revisão sistemática de literatura realizada por meio das bases PUBMED, LILACS e SciELO, em julho de 2024, de artigos no período de 2019-2024. A busca dos estudos foi feita na língua inglesa com os seguintes descritores: "aprepitant" AND "PONV" AND "prophylaxis". A triagem, elegibilidade e extração dos dados foram feitas por três revisores. Ao todo, foram encontrados 26 artigos, dos quais 22 foram excluídos após a leitura do título e resumo. Durante a leitura completa dos demais, nenhum artigo foi eliminado por critérios de exclusão e assim, apenas 4 artigos foram incluídos nesta revisão. Observou-se que o aprepitanto é mais efetivo na NVPO tardia e o seu uso com o palonosetron não reduziu a incidência de NVPO. Ademais, o aprepitanto demonstrou ser mais efetivo do que a ondasetrona na prevenção de NVPO. Portanto, o aprepitanto foi efetivo na redução da gravidade e incidência de NVPO e na recuperação da qualidade de vida do paciente.
Diagnóstico clínico e manejo terapêutico da Infiltração Linfocítica de Jessner: um relato de caso
Authors: Dodó Francisco Diemeson Bezerra , Farias Leonildo Peixoto , Santos Ana Flávia Resende , André Leandro Oliveira , Marques Jonatas Monteiro , Oliveira Raimunda Moreira de , Moita Fernando Ériton Aguiar , Menezes Letícia Soares Teles de , Sousa Luis Felipe Matos de , Paz Rogério Bernardo de Oliveira , Leite Gustavo dos Reis , Amora Lígia Garcia , Alves Paulo Wendel Cândido , Canto João Vitor de Aguiar Martins , Silva Gabriel de Sousa
Published: August 2024

A infiltração linfocítica de Jessner (ILJ) é uma doença cutânea rara benigna, caracterizada como uma desordem infiltrativa de células T, que se manifesta como pápulas ou placas não descamativas, eritematosas e, geralmente, assintomáticas. Nesse contexto, o objetivo deste trabalho é descrever um caso clínico de ILJ a partir das manifestações sintomáticas do quadro, bem como a abordagem diagnóstica e manejo terapêutico.
Panorama das disfunções tireoidianas em crianças com Síndrome de Down
Authors: Prestes Ananda Carolina Reis , Lopes Manuela Chaves Marques , Diogo Leonardo Rodrigues Ferreira , Gonçalves Fernando Leite , Begot Maria Beatriz Pinheiro , Sousa Alder Mourão de , Hanna Leila Maués Oliveira , Acatauassú Sarah Tuma
Published: August 2024

A Síndrome de Down (SD) está associada a várias comorbidades, incluindo anomalias cardíacas, respiratórias, e disfunções endócrinas, especialmente tireoidianas. Pacientes com SD, frequentemente, apresentam redução de T3 e T4, ocasionando atrasos mentais, baixa estatura e metabolismo lento. Porém, o manejo dessa condição nesse público continua desafiador. Objetiva – se analisar a relação complexa entre crianças com SD e disfunções tireoidianas, para melhorar as condições de saúde e manejo dessa população. Para tanto, procede-se à revisão integrativa da literatura de caráter observacional, qualitativo e transversal, baseada na pergunta norteadora: "Existem alterações na glândula tireoide de crianças com trissomia do cromossomo 21 que podem repercutir na saúde e manejo desse público?". As bases de dados utilizadas foram PubMed e BVS, a partir dos descritores “Thyroid Gland” AND “Down Syndrome”, indexados no DeCS. Foram incluídos estudos no período de 2013 a 2023, em português ou inglês, disponíveis gratuitamente e de forma completa. Desse modo, encontraram – se 92 artigos, dos quais descartaram – se 36 por estarem indisponíveis gratuitamente, 24 que não corresponderam ao tema de interesse, 13 duplicatas e 7 revisões de literatura, sobrando 12 para leitura completa. Logo, é possível concluir que este trabalho versa sobre a complexão ligação entre SD e disfunções tireoidianas, contribuindo para uma melhor compreensão pelos profissionais de saúde e pela sociedade, com o intuito garantir a saúde e o manejo dos pacientes que possuem essa condição.
O impacto da telemedicina na eficácia do tratamento para pacientes com tendências hipocondríacas
Authors: Silva Amanda Rodrigues da , Oliveira Ana Beatriz Santos de , Sperandio Ana Clara Messias , Barbosa Danilo Asafe Pantoja , Querido Jessica Alves , Silva Luana dos Santos , Tavares Lucas Torres , Campos Luiza Bastos , Camelo Rafael Carlheiros , Medeiros Renan Antônio Corrêa
Published: August 2024

INTRODUÇÃO: O trabalho de pesquisa explora o uso da telemedicina para o tratamento de pacientes com tendências hipocondríacas. A discussão destaca a urgência dos pacientes hipocondríacos em receber atendimento médico para acolher sua preocupação excessiva com a saúde, associada a praticidade e agilidade que a telemedicina pode fornecer. Vários benefícios, como a acessibilidade para pessoas com limitações físicas e financeiras fornecida por essa estratégia terapêutica, são discutidas como fatores que instigam a adesão dos pacientes psiquiátricos para o uso da telemedicina. A discussão também menciona as responsabilidades do médico em adequar seu atendimento e analisar a necessidade do paciente em realizar essa forma de acompanhamento, com base no quadro clinico do paciente, sem que aja prejuízos a saúde própria e de terceiros. No geral, o trabalho fornece informações valiosas sobre o uso da tecnologia para atendimento médico e contribui para o avanço dos conhecimentos da telemedicina para os pacientes hipocondríacos. METODOLOGIA: Esta revisão sistemática da literatura buscou identificar estudos relevantes sobre a importância da telemedicina e o tratamento de pacientes psiquiátricos com tendencias hipocondríacas. Foram incluídos estudos clínicos randomizados, revisões sistemáticas e estudos observacionais publicados nos últimos 10 anos que abordaram a telemedicina. Os resultados encontrados forneceram informações sobre as implicações, os benefícios e indicações da telemedicina associadas as demandas, preocupações e necessidades dos pacientes psiquiátricos em nível ambulatorial. DISCURSÃO: A análise dos dados revela o uso da telemedicina como um instrumento estratégico, para o acompanhamento dos pacientes psiquiátricos, e a discussão aborda, as características dessa abordagem que favorecem a relação medico paciente, bem como as limitações do seu exercício. Além disso, a discussão descreve as responsabilidades do médico em orientar e aconselhar o paciente sobre as indicações do atendimento online, prezando a saúde e bem estar geral do paciente. Em suma, a prática de telemedicina se apresenta como uma opção viável para diminuir a obsessão dos pacientes hipocondríacos com a saúde e no acompanhamento dos pacientes psiquiátricos. CONCLUSÃO: O trabalho proporciona informações importantes sobre a telemedicina e contribui para ampliação dos conhecimentos dessa abordagem para os pacientes hipocondríacos. Ao explorar os benefícios, limitações e obrigações dessa prática, promove-se a utilização correta pelos profissionais e pacientes, tornando a telemedicina mais acessível e segura. Com a evolução dos estudos, espera-se que o acompanhamento de forma remota seja efetivo e gere melhores perspectivas para os pacientes hipocondríacos sobre seu estado de saúde.
Mecanismos de ação do endolaser na harmonização orofacial - revisão de literatura
Authors: Silva João Victor Pessoa da , Moura Rafaella Ferreira , Silva Jadson Mathyas Domingos da
Published: August 2024

A harmonização orofacial é uma área em constante progresso com procedimentos visando melhorar a estética e função da região bucal e facial. O endolaser, uma tecnologia de laser de baixa potência, emerge como uma ferramenta promissora nesse contexto, oferecendo diversos benefícios na pele e nos tecidos faciais. Seus principais mecanismos de ação incluem o estímulo à produção de colágeno, a melhora da circulação sanguínea, a ação anti-inflamatória e analgésica, e o estímulo à regeneração tecidual. Assim, esse trabalho teve como objetivo analisar a literatura a respeito dos benefícios do endolaser na harmonização orofacial. Trata-se de uma revisão de literatura realizada por meio do uso de bases de dados como SciELO, PubMED e Google Acadêmico. Verificou-se que essa tecnologia possui abordagem não invasiva e eficaz, além de ser uma opção versátil para profissionais da estética e saúde facial. Por fim, pode-se considerar que o endolaser estimula a formação de colágeno, amplificando a espessura da derme e tornando assim a pele mais firme.
Unusual presentation of infectious Endocarditis: case report
Authors: Salfrant Lester Sulet , Damázio Laila Cristina Moreira
Published: August 2024

Infectious Endocarditis is the involvement of the endocardium and mainly the heart valves by germs that, when multiplying, form vegetation. Its presentation is heterogeneous and varies from non-specific symptoms such as fever, weight loss and anemia to local and systemic complications such as intracardiac abscess, atrioventricular block, heart failure, acute myocardial infarction, pericardial effusion, distant embolic phenomena, and renal failure, among others. The diagnosis is made using the Duke-ISCVID 2023 Criteria, which classifies it as a definitive or possible diagnosis. Treatment involves intravenous antibiotic therapy for at least four weeks following the negative blood culture result. On some occasions, a surgical approach is necessary. Even with all established efforts, mortality remains high and is dependent on the etiological agent, the delay in diagnosis and the delay in starting treatment. This report addresses the case of a 57-year-old patient, treated in an emergency department, with rare complications of infective endocarditis (myocardial infarction due to septic coronary embolism and purulent pericarditis with echocardiographic signs of cardiac tamponade). Both blood cultures and pericardial fluid cultures grew Enterococci sp, typical of infective endocarditis. Right and left coronary angiography with left ventriculography and transthoracic echocardiography were essential tools to clarify this case.
Análise de custos do trabalho temporário: estudo de caso em uma indústria do agronegócio
Authors: Schuster Júlia de Souza , Coser Tiago
Published: August 2024

O trabalho temporário é uma realidade em alguns processos do agronegócio, embora a automatização esteja ganhando espaço neste contexto. Quando se trata da cultura da maçã a colheita ainda é predominantemente realizada de forma manual. Frente a isso, o objetivo deste trabalho é analisar o custo do trabalho temporário, visto que no período de safra da maça os produtores necessitam realizar este tipo de contratação no processo de colheita, principalmente pela escassez de mão de obra na região. Este estudo trata-se de uma pesquisa descritiva com abordagem qualitativa, desenvolvida por meio de estudo de caso único realizado no primeiro semestre de 2023, abrangendo os dados do período de fevereiro a abril do ano de 2023, considerando a contratação de 971 funcionários. Foram considerados os elementos de custos de salário, encargos sociais, custo de alimentação, transporte, contratação, férias e 13° salário. Observou-se que a empresa possui informações dos principais custos de contratação, não considerando todos os elementos de custo, bem como não os apropriando devidamente em sua contabilidade, o que dificulta a análise e interpretação dos dados de custos para a tomada de decisão. Identificados os principais elementos de custos, os resultados indicaram um custo mensal por trabalhador temporário de R$ 3.360,31, e um custo contratual dos três meses de R$ 9.788.573,43. Para fins comparativos, o custo do trabalho temporário local, mesmo município e região, totalizou R$ 7.950.075,61, representando uma possível redução de 18,7% no custo total do contrato de trabalho.
Effects of soybean-oil and emulsifiers mixture on rheological properties of oil-in-water emulsions
Authors: Leiva-Vega Javier , Pino-Acuña Daniela , Herrera-Lavados Carolina , Silva-Ferrer Danela
Published: August 2024

The effects of soybean-oil and emulsifiers mixture on rheological properties of oil-in-water emulsions were investigated. Polysorbate-80 and sorbitan-monooleate in the ratio 1:3 were added to stabilize a soybean-oil emulsion by high-pressure homogenization at 50 and 100 MPa. Particle size and rheological properties were measured. The z-average size value showed all the droplets ranging from 295.5 to 302.3 nm. The emulsions were Newtonian and non-Newtonian pseudoplastic at 50 MPa, although at 100 MPa exhibited a Newtonian behavior, preferably. The highest concentrations of soybean-oil and emulsifiers mixture showed semi-solid emulsions (at 50 MPa), and the lower concentrations of soybean-oil and emulsifiers mixture, showed semi-solid emulsions (at 100 MPa), however, elastic character predominated over viscous character (G’>G’’), for both pressures. In conclusion, the emulsion systems were nanoemulsions and their droplet size distribution was bimodal. The nanoemulsions had a non-Newtonian behavior for both pressures, although at 100 MPa the emulsions were Newtonian.
Heuristic Availability Bias's Effect on Investment Decisions: Moderating Effect of External Locus of Control
Authors: IZHAR AHMAD  , Muhammad Hamza Haroon
Published: August 2024

In this work, the impact of heuristic availability bias on financial decisions is attempted to be quantified. Besides, the external locus of control as a moderating variable has also been analyzed. The population of the research consists of investors who made investments in the Pakistan Stock Exchange. But 400 responses make up the sample. The responders got questionnaires online. A total of 293 complete replies were received. Moderation and regression analysis of the data were performed. The findings indicate that availability bias greatly affects investors' decision-making process. Later research revealed that locus of control affects both financial responsibilities and availability bias. The government, the State Bank of Pakistan, Pakistan Stock Exchange, and educational institutions all advised giving investors education, protection, and awareness high priority. Better still, they could choose assets that would maximize return.
A Study On How New Media Is Impacting On The Irish Public Relations Industry
Authors:   ,   Cork Institute of Technology, Murphy Ciara
Published: August 2024

"This thesis looks at how new media is impacting on the public relations industry in Ireland. It attempts to identify if Irish practitioners believe that the Internet is an important tool for two-way communication purposes, to identify the implications of new media on the practice of public relations, to determine how new media is impacting on the mass media in Ireland and to determine how social media is currently being implemented by PR practitioners in Ireland. The study attempts to fill a gap in public relations research and professional literature because there is no organising framework that merges new technologies with existing communication tools used in public relations. A qualitative research method was chosen and the primary method of research was the in-depth interview. Interviews were carried out with six Irish PR practitioners both in in-house and consultancy roles. The study investigated PR practitioners’ perceptions of the Internet as a communications tool and how new media is viewed and regarded by them to gain a better understanding of how they are incorporating it into their communication strategies. The research findings show that practitioners believe that the Internet is useful for two-way communication. It was found that new media is definitely posing threats for the physical media. It was also discovered that practitioners are not applying the new Web 2.0 technologies to the greatest effect. It can be concluded that Irish PR practitioners are currently using the Internet as a two-way communications tool. They deem there is enough effort being made to educate the industry on the benefits of new and social media. Irish practitioners also think that new media is posing a threat to traditional media but believe it will still play an active role in Irish public relations for the foreseeable future. Practitioners in Ireland have a broad overall knowledge of the many social media tools and their benefits. However they are not all applying them in the most effective way. They are aware of the potential of new media but if they are to be successful in the Irish public relations industry they must embrace it fully."
The Changing Face Of Print Media : How New Attitudes To Communication By Both Industries Could Affect Public Relations.
Authors:   ,   Cork Institute of Technology, Kennedy Paul
Published: August 2024

Digital media is a phenomenon that has affected many industries, particularly both print media and public relations. Communication is something is at the heart of both of these industries. In this thesis, communication theory is explored in a digital media and print newspaper context, in relation to these industries. It is explored how both industries are using similar techniques, and the merit of these approaches are investigated and discussed. Included in this are the value of new news outlets and new and old business models. Opinions on modem media relations are investigated and the weight of third- party endorsement is judged within these new online environments