bluuebunny/crossref_metadata_2025 huggingface dataset:
Symptom-level network analysis distinguishes the unique associations of repetitive negative thinking and experiential avoidance on depression and anxiety in a transdiagnostic clinical sample
Authors: Hsu Kean J. , Mullarkey Michael C , Dobias Mallory , Beevers Christopher G , Björgvinsson Thröstur
Published: July 2019

Repetitive negative thinking and experiential avoidance have been hypothesized to be related, transdiagnostic maintenance factors for depression and anxiety. Work to date has not examined these maintenance factors in a comorbid clinical sample using a symptom-level approach. Adults presenting for treatment to an intensive CBT program (n = 492) completed measures of depression and anxiety symptom severity, repetitive negative thinking, and experiential avoidance. Permutation testing indicates that repetitive negative thinking improved the predictability of excessive worrying and concentration, whereas experiential avoidance improved the predictability of feeling like a failure, difficulties relaxing, and being afraid something bad was going to happen. Applying network analysis helps to more precisely identify which symptoms of depression and anxiety are associated with transdiagnostic maintenance factors, thus providing insight into how these factors may contribute to the maintenance of co-occurring disorders.
Biomechanical factor affecting Baseball Pitching Velocity
Authors: Ota Yasushi , Kuriyama Ryoga
Published: July 2019

In baseball, pitchers have a central role and high-speed pitching is desirable. So far, several studies of the physical factors related to pitching form with the aim of improving the speed of pitched balls have been conducted. In this study, we used a motion capture to acquire three-dimensional (3D) time series data related to the speed of pitched balls and performed a kinetics analysis by using these acquired data. The acquired data were divided into five pitching phases: wind up, early cocking, late cocking, acceleration, and follow through. Our analysis identified the body parts that contribute to increasing the speed of pitched balls, i.e., the speed of rotation of individual joints and the timing/phase when power can be applied. Especially, by examining joint angular velocity and joint force, we showed that the speed of pitched balls is determined by the action of the upper limbs as well as the coordinated action of the whole body, particularly the lower limbs and the trunk.
Economic Analysis on the Production of Large Cardamom in Panchathar, Nepal
Authors: Baniya A. K. , Karki S. , Dhungana S. M. , Rizal G.
Published: July 2019

Available with full text.
Assessing the Structure and Factors Affecting Agrobiodiversity of Home Garden at Katahari Rural Municipality, Province 1, Nepal
Authors: Khanal S. , Khanal D. , Kunwar B.
Published: July 2019

Available with full text.
AS TECNOLOGIAS DIGITAIS PARA O ENSINO DE CIÊNCIAS: PERCEPÇÕES, DESAFIOS E POSSIBILIDADES PARA O CONTEXTO EDUCACIONAL
Authors: Coelho Neto João , Bazan Blanco Marilia , Araújo Roberta Negrão de
Published: July 2019

O uso das Tecnologias Digitais pode ser um diferencial para o ensino, principalmente para o de Ciências, visto a interação e possibilidades de utilização deste instrumento em sala de aula. Dessa forma, este artigo visa identificar quais são as percepções e desafios do uso das tecnologias digitais para o ensino de Ciências, principalmente com discentes de um curso de pós-graduação em Ensino que atuam ou já atuaram no ensino de Ciências, principalmente em escolas públicas com o uso das tecnologias em seu contexto. O encaminhamento metodológico utilizado foi o da pesquisa qualitativa, e como instrumento de coleta de dados utilizou-se um questionário semiestruturado e para a análise dos resultados, a Análise Textual Discursiva. Como resultados preliminares identificou-se que a utilização dos recursos pode ser um diferencial para o ensino de Ciências, porém, essa utilização ainda é um desafio nas escolas públicas no Brasil, na visão dos participantes desta pesquisa, em função da capacitação dos professores e da disponibilidade e manutenção dos equipamentos.
FORMAÇÃO DE PROFESSORES DE CIÊNCIAS PARA A PROMOÇÃO DO PENSAMENTO CRÍTICO NO BRASIL: ESTADO DA ARTE
Authors: Da Costa Güllich Roque Ismael , Vieira Rui Marques
Published: July 2019

A perspectiva do Pensamento Crítico (PC) como organizador do currículo de ensino e da formação inspira avanços em estudos brasileiros, a fim de verificar/produzir/compreender como desenvolver estratégias que promovam uma formação crítica em Ciências. Assim, a partir de um estudo bibliográfico de revisão da literatura na <a href="http://www.google.com.br/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&sqi=2&ved=0CB0QFjAA&url=http%3A%2F%2Fwww.scielo.org%2F&ei=QVc9VcPfK9HksATin4HIBw&usg=AFQjCNEnNAurIe91oKP97ilFH9ltH9ncGA&sig2=rmL2xGbo71AfO3huVNQPPQ&bvm=bv.91665533,d.cWc">Scientific Electronic Library Online (SciELO) e  no Banco de Teses da CAPES[1], tendo como palavras-chave: pensamento crítico (PC) e pensamento, este artigo tem como objetivo apresentar e discutir as principais produções científicas que tem o escopo no PC como estratégia de ensino e formação de professores circunscritas a área das Ciências da Natureza e suas Tecnologias (CNT). O panorama inicial demonstrou que os trabalhos são em número reduzido, sendo vários destes de autores estrangeiros o que evidencia o estado inicial desta linha de pesquisa do ensino de Ciências em contexto brasileiro.

[1] Cito o portal da Coordenação de Aperfeiçoamento de Pessoal de Nível Pessoal (CAPES).
O QUE OS ALUNOS ESPERAM DO ÚLTIMO ESTÁGIO SUPERVIONADO NA LICENCIATURA EM CIÊNCIAS BIOLÓGICAS?
Authors: Da Silva Fredson Murilo , De Lima Gênesis Medeiros , De Melo Barros Marcos Alexandre
Published: July 2019

O presente artigo tem o objetivo de analisar as expectativas dos alunos do curso de Licenciatura em Ciências Biológicas da Universidade Federal de Pernambuco com relação a última disciplina de Estágio em Ensino de Biologia. Partindo de um levantamento de dados sobre a importância do estágio supervisionado na formação inicial dos professores, aplicamos um questionário aos alunos do último período, elencando dados qualitativos acerca dos seus anseios para com a disciplina de Estágio em Ensino de Biologia 4 oferecida pela coordenação do curso. Observamos que os estágios não se mostram suficientes para suprir a formação de docentes que ingressem diretamente no mercado de trabalho. Assim, o estágio não vem cumprindo seu papel na formação dos professores e a residência docente em biologia pode ser uma alternativa para suprir esta necessidade.
CONCEPÇÕES DOS PROFESSORES DOS ANOS INICIAIS SOBRE A FORMAÇÃO DE CONCEITOS CIENTÍFICOS
Authors: Silva Sorái Vaz da , Lorenzetti Leonir
Published: July 2019

O presente trabalho tem o objetivo de analisar as concepções de professores dos anos inicias que atuam nas escolas públicas municipais da cidade de Quatro Barras-PR sobre a formação de conceitos científicos. Face a tímida análise do tema nos trabalhos publicados nos Enpec’s dos últimos dezoito anos, verificou-se a importância de mapear esta visão por parte dos professores. A coleta de dados foi realizada por meio de um questionário, composto de onze questões, que foi respondido por 40 professores que atuam nos anos inicias. Os dados foram analisados com base na metodologia de análise de conteúdo proposta por Bardin. Os resultados encontrados sinalizam uma deficiência na concepção de formação de conceitos em ciências naturais, sinalizando que um dos fatores é a deficitária formação destes professores tanto na formação inicial quanto na Formação Continuada. Assim o mapeamento das concepções dos professores proporcionou elementos para a elaboração de curso de formação continuada que contribua para a melhoria do ensino de ciências nos anos iniciais.
RELAÇÕES ENTRE TECNOLOGIAS DIGITAIS E O APRENDIZADO ESCOLAR
Authors: Lopes Leticia Azambuja , Martini João Carlos , Campos Lopes Paulo Tadeu
Published: July 2019

A pesquisa aborda como os estudantes do ensino médio utilizam as ferramentas das Tecnologias Digitais (TD) e quais as suas relações com a aprendizagem em sala de aula. Para tanto, foi elaborado um questionário online sobre o uso de tecnologias que foi respondido por 22 estudantes do primeiro ano do ensino médio de uma escola particular em Canoas, RS. Os resultados indicam que os estudantes tem apropriação das TD, fazem uso para estudo, mas ainda não as veem efetivamente com metodologia de estudo em sala de aula, visto que, ainda não são totalmente utilizadas pelos professores. Assim, é preciso um esforço conjunto entre escola e o profissional da educação, quando se trata da inclusão da tecnologia no ensino, e que ignorar a utilização das TD, elemento que já faz parte da sociedade contemporânea, seria como ignorar a evolução na educação.
Factors Affecting University Selection: Empirical Evidence from Hyderabad, Pakistan
Authors: Uddin Ikram , Amjad Hafsah , Memon Rawah , Pujwani Zohaib , Rahar Usman
Published: July 2019

Selection in Hyderabad, Pakistan.

Method/Design: There are three independent variables selected, which are Financial Variable, Institutional Awareness and Institutional characteristics and the selected dependent variable is University selection. A 5 Likert scale adopted questionnaire was used as the instrument for the research. The data was gathered from a sample of 130 students and was analyzed by applying reliability (Cronbachâ€™s Alpha) and Multiple regression in SPSS version 20.

Findings: It was concluded from the findings of the research that Financial Variable and Institutional characteristics have a positive and significant impact on university selection. Whereas, Institutional Awareness was found to have negative and insignificant impact on university selection.

Practical Implications: It is recommended that universities should consider these factors in order to increase the enrollment in their university. This will also improve the name and reputation of the university. Students should also consider these factors in order to select a proper university.
Pengaruh Posisi Pronasi Pada Bayi Prematur Terhadap Perubahan Hemodinamik
Authors: Anggraeni Lina Dewi , Indiyah E Sri , Daryati Susi
Published: July 2019

Prematur merupakan bayi yang lahir sebelum usia kehamilan kurang dari 37 minggu. Lebih dari 75% bayi prematur mengalami gangguan pernafasan. Bayi prematur harus mendapat perhatian dan tatalaksana yang baik setelah lahir, untuk menghindari terjadinya masalah pernafasan yang lebih berat. Salah satu tatalaksana yang dapat menyokong terapi oksigen adalah pengaturan posisi pada bayi, yakni posisi pronasi. Posisi pronasi dilakukan untuk mengurangi kompresi abdomen dan memperbaiki fungsi pernapasan dan stabilitas kardiovaskuler. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian posisi pronasi pada bayi prematur terhadap frekuensi nafas, frekuensi denyut jantung dan SpO2. Penelitian ini dilakukan pada bayi prematur yang dirawat di ruang neonatus dengan 32 sampel. Penelitian dilakukan pada bulan Maret – Mei 2018. Penelitian dilakukan dengan penelitian kuantitatif dengan menggunakan metode Quasi-Eksperimental dengan one group Pre-Post Intervensi. Hasil penelitian didapatkan ada pengaruh yang signifikan posisi pronasi pada bayi terhadap peningkatan saturasi oksigen pre-post intervensi 1 dan 2 jam pertama (Pv 0.00), ada pengaruh yang signifikan posisi pronasi pada bayi terhadap HR pre-post intervensi 1 jam pertama (Pv 0.027) dan 2 jam pertama (Pv 0.008). Posisi pronasi dapat diimplementasikan pada bayi premature untuk meningkatkan status hemodinamik yang berdampak pada kualitas hidup bayi.

Premature is a baby born before pregnancy is less than 37 weeks. More than 75% of premature babies had respiratory problems. Premature babies must get good attention and management after birth, to avoid more severe respiratory problems. One of the procedures that can support oxygen therapy is the regulation of position in the baby, namely the pronation position. The pronation position is performed to reduce abdominal compression and improve respiratory function and cardiovascular stability. This study aims to determine the effect of giving pronation position in premature infants on the frequency of breath, heart rate and SpO2. The study was conducted in preterm infants who were treated in the neonates room with 32 samples. The study was conducted in March - May 2018. The study was conducted with quantitative research using the Quasi-Experimental method with Independent Test and Pre-Post Intervention. Results: There was a significant effect of pronation position on infants on the increase in oxygen saturation pre-post intervention 1 and the first 2 hours (Pv 0.00), there was a significant influence on pronation position in infants on the first 1 hour HR pre-post intervention (Pv 0.027) and first 2 hours (Pv 0.008). The position of pronation can be implemented on a premature baby to increase haemodynamic status that have an impact on the quality of life of infants.
Penilaian Kualitas Implementasi Corporate Social Responsibility Pada Perusahaan Pertambangan di Indonesia Berdasarkan Indeks Global Reporting Initiatif (GRI)
Authors: Suharlinas
Published: July 2019

Tujuan penelitian ini adalah untuk melihat implementasi Corporate Social Responsibiliy (CSR) perusahaan sesuai dengan indeks Global Reporting Inisiative (GRI) kemudian melihat apakah CSR yang dijalankan perusahaan sesuai dengan bidang usaha perusahaan dan kebutuhan masyarakat. Pendekatan penelitian yang digunakan adalah penelitian deskriptif. Objek dari penelitian ini adalah PT Antam, PT Bukit Asam, PT Medco Energy, dan PT Indo Tambangraya Megah. Keempat perusahaan ini dipilih karena sudah memenuhi kriteria pengambilan sample. Hasil penelitian menunjukkan bahwa PT Antam cukup memenuhi poin- poin dari indeks GRI sedangkan tiga perusahaan lainnya kurang memenuhi standar tersebut. Namun keempat perusahaan tersebut telah taat terhadap peraturan daerah tempat mereka beroperasi. Hal tersebut terlihat dari kegiatan CSR yang dijalankan perusahaan seperti pembangunan sarana dan prasarana, pemberian beasiswa dan pelatihan kepada karyawan dan masyarakat, pemberdayaan masyarakat seperti pemberian modal usaha mandiri, pembibitan sayur dan ikan, dan pelestarian lingkungan. PROPER yang diperoleh keempat perusahaan tersebut juga terbilang baik
Caracterización clínica y demográfica de la hospitalización psiquiátrica infantojuvenil en un hospital general
Authors: Duarte Viviana , Zelaya Lourdes
Published: July 2019

Introducción: Se implementan actualmente nuevos modelos de hospitalización psiquiátrica infantojuvenil, para hacer frente a la creciente demanda de recursos de atención psiquiátrica intensiva requeridos por esta población. Objetivo: Identificar las características clínicas y demográficas de los niños y adolescentes con diagnóstico psiquiátrico hospitalizados en Salas de Pediatría de un Hospital General Pediátrico. Metodología: Estudio descriptivo, retrospectivo de corte transversal, en base a historias clínicas de 180 casos hospitalizados en el periodo enero-agosto del año 2015.Variables: Edad, sexo, procedencia, motivo de ingreso, diagnóstico psiquiátrico, tipo de patología psiquiátrica, medicación, servicio desde el cual se indicó la evaluación psiquiátrica, días de hospitalización, seguimiento y derivación. Resultados: En el periodo de estudio se identificaron 180 pacientes hospitalizados con uno o más diagnósticos psiquiátricos, de los cuales 67.2% eran del sexo femenino. La mediana de la edad fue de 13 años. De un total de 387 diagnósticos constatados, los seis diagnósticos psiquiátricos más frecuentes fueron: los diferentes tipos de maltrato infantil (42,89%), los trastornos depresivos (21,71%), los intentos suicidas (8,27%), el trastorno adaptativo (4,39%) y el trastorno por estrés post traumático (4,13%). El 56% presentó comorbilidad de dos o más diagnósticos psiquiátricos.  La internación fue indicada principalmente desde las Salas de Urgencias (67,3%). El 54,4% (98/180) estuvo hospitalizado de 1 a 3 días. En el 47,2% de los casos se indicó psicofarmacoterapia. Conclusión: Se registró mayor frecuencia de diagnóstico psiquiátrico en adolescentes y en el sexo femenino. La sospecha de abuso sexual infantil representó un frecuente motivo de ingreso. Las distintas formas de maltrato Infantil, los trastornos depresivos y los intentos suicidas, al constituir los diagnósticos psiquiátricos más frecuentes, requieren parámetros de evaluación y tratamiento específicos y efectivos para su adecuado manejo multidisciplinario. Las Salas de Urgencias Pediátricas cumplen un importante rol como puerta de entrada de estos pacientes al sistema de salud y al continuum de servicios de atención a la salud mental.

Correspondencia: Viviana Duarte Correo: viv6du@hotmail.com

Conflicto de interés: Los autores declaran no poseer conflicto de interés

Recibido: 13 /05/ 2019 Aceptado: 18/07/2019
Penyediaan Ruang Terbuka Hijau dengan Pendekatan Kota Hijau pada Perkotaan Martapura
Authors: Caesarina Hanny Maria , Rahmani Dienny Redha
Published: July 2019

Seiring meningkatnya urbanisasi, meningkat pula berbagai permasalahan yang dihadapi perkotaan terutama penurunan kualitas lingkungan. Konversi lahan dari ruang terbuka hijau menjadi lahan terbangun memunculkan efek urban heat island. Konsep kota hijau  dengan penyediaan ruang terbuka hijau publik yang memadai merupakan salah satu upaya untuk mengantisipasi efek tersebut. Penelitian ini bertujuan untuk mengidentifikasi dan memetakan penyediaan ruang terbuka hijau publik pada perkotaan Martapura. Metode yang digunakan adalah deskriptif kuantitatif dengan pendekatan kota hijau. Hasil penelitian menunjukkan bahwa kawasan perkotaan Martapura memerlukan penambahan ruang terbuka hijau dalam bentuk rth aktif dan rth pasif.
Presence of aspartic dipeptides with β peptide bond and/or D-aspartyl residue in rat blood after ingestion of porcine liver protein hydrolysate
Authors: Ejima Akika , Yamada Kotaro , Sato Kenji
Published: July 2019

Background: Animal experiments have demonstrated that oral administration of a porcine liver protein hydrolysate (LPH) ameliorates alcohol-induced liver toxicity, as well as exercise- and concanavalin A-induced low locomotor activity in mice. The peptides responsible for the beneficial effect have not yet been identified. Recently, presence of food-derived peptides in human blood has been detected post ingestion of other food protein hydrolysates. These peptides are prolyl, hydroxyprolyl, or pyroglutamyl di- and tri-peptides, and resist exopeptidase digestion. Some of these peptides exert significant biological roles in vitro and in vivo, which have been associated with the biological response post ingestion. The objective of the present study was to identify the food-derived peptides in rat blood after ingestion of LPH.Results: In the in vitro exopeptidase digest of LPH, pyroglutamyl, prolyl, hydroxyprolyl, and aspartic dipeptides were identified. The aspartic peptides (Asp-Val, Asp-Ile, Asp-Leu, and Asp-Phe) showed multiple peaks by LC-MS/MS, indicating the presence of isomers. Four isomers with L- and D-aspartyl residues, and α and β peptide bonds were present in each sequence. After administration of LPH, the amounts of unusual aspartic dipeptides with β peptide bond and/or D-aspartyl residue significantly increased in rat plasma, while those of the other usual aspartic peptides did not.Conclusions: Racemization and isomerization of aspartyl residues in peptides occur during the preparation of LPH or following its digestion. The unusual aspartic peptides have a potential for carrying out diverse biological activities.Key words: Peptide, food protein hydrolysate, aspartic, isopeptide, bioavailability, D-amino acid
Anti-inflammatory and anti-allergic activities of Skipjack tuna (Katsuwonus pelamis) dark muscle hydrolysates evaluated in cell culture model
Authors: Chansuwan Worrapanit , Upunqui Chutha Takahashi , Chinachoti Pavinee
Published: July 2019

Background: Oxidative stress and inflammation are inextricably linked and play major roles in the onset and development of Non-communicable diseases (NCD) which are the most common cause of death and disability in modern world. Hydrolyzed proteins have also been suggested to be used to manage adverse food allergic reaction. Therefore, this study aimed to investigate anti-inflammatory and anti-allergy activities of dark muscle tuna hydrolysates using biological cell line systems as a function of enzyme, the extent of hydrolysis and molecular weight range.Methods: Dark muscle tuna hydrolysates were prepared with two different enzyme types; Alcalase and Flavourzyme. Anti-inflammation activity was measured by inhibitory effect of nitric oxide (NO) production on lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells. Anti-allergy was determined from ability of hydrolysates to inhibit b-hexsosaminidase (b-HEX) release from RBL-2H3 mast cells. Cytotoxicity was also investigated in both RAW 264.7 macrophage cells and RBL-2H3 mast cells.Results: No cytotoxic effect on RAW 264.7 macrophage cells and RBL-2H3 mast cells was observed. The NO inhibition and b-HEX release were found significant in dose dependent manner (p<0.05). Alcalase hydrolysates demonstrated greater anti-inflammatory and anti-allergic activities than Flavourzyme hydrolysates (p<0.05). IC50 of both effects were lower than the unhydrolyzed control, > 45.44 mg/ml for NO inhibition and > 65.23 mg/ml for b-HEX release inhibition. These effects increased with the extent of hydrolysis and enzyme concentration. The peptide of lowest molecular weight range (< 3 KDa) was highest in anti-inflammatory and anti-allergic actions. Reducing secretion of TNF-a, IL-6 and IL-1b was found greater in Alcalase hydrolysate than Flavourzyme one.Conclusions: Skipjack tuna dark muscle hydrolysates from Alcalase resulted in peptides with anti-inflammation activity, as determined by NO production in LPS-stimulated RAW 264.7 macrophage cells and anti-allergic properties as measured by a suppression of degranulation of sensitized RBL-2H3 cells. Anti-inflammatory effect may be due to their anti-oxidative capacity and relevant inflammatory factors attenuated with hydrolysate by reducing secretion of pro-inflammatory cytokine (TNF-a, IL-6 and IL-1b). Inhibition of b-HEX release by peptides may be due to membrane-stabilizing action or/and blockade of IgE antibody at fragment region.Keywords: Skipjack tuna, anti-inflammation, enzymatic hydrolysate, dark muscle, anti-allergy
Ribosylation-Derived Advanced Glycation End Products Induce Tau Hyperphosphorylation Through Brain-Derived Neurotrophic Factor Reduction
Authors: Wu Beibei , Wang Yujing , Shi Chenggang , Chen Yao , Yu Lexiang , Li Juan , Li Weiwei , Wei Yan , He Rongqiao
Published: July 2019

Advanced glycation end products (AGEs) have been implicated in the disease process of diabetes mellitus. They have also been found in senile plaques and neurofibrillary tangles in the brains of Alzheimer’s disease patients. Furthermore, abnormally high levels of D-ribose and D-glucose were found in the urine of patients with type 2 diabetes mellitus, suggesting that diabetic patients suffer from dysmetabolism of not only D-glucose but also D-ribose. In the present study, intravenous tail injections of ribosylated rat serum albumin (RRSA) were found to impair memory in rats, but they did not markedly impair learning, as measured by the Morris water maze test. Injections of RRSA were found to trigger tau hyperphosphorylation in the rat hippocampus via GSK-3β activation. Tau hyperphosphorylation and GSK-3β activation were also observed in N2a cells in the presence of ribosylation-derived AGEs. Furthermore, the administration of ribosylation-derived AGEs induced the suppression of brain-derived neurotrophic factor (BDNF) and tropomyosin-related kinase B (TrkB). Both GSK-3β inhibition and BDNF treatment decreased the levels of phosphorylated tau in N2a cells. In particular, the administration of BDNF could rescue memory failure in ribosylated AGE-injected rats. Ribosylation-derived AGEs downregulated the BDNF-TrkB pathway in rat brains and N2a cells, leading to GSK-3β activation-mediated tau hyperphosphorylation, which was involved in the observed rat memory loss. Targeting ribosylation may be a promising therapeutic strategy to prevent Alzheimer’s disease and diabetic encephalopathies.
Changes in the phenolic profile, antioxidant capacity and in vitro bioaccessibility of two Algerian grape varieties, Cardinal and Dabouki (Sabel), during the production of traditional sun-dried raisins and homemade jam
Authors: Zoubiri Lamia , Bakir Sena , Barkat Malika , Carrillo Celia , Capanoglu Esra
Published: July 2019

BACKGROUND:

Excessive production of grape is valorized by traditional drying and homemade jam production in some regions of Algeria.

OBJECTIVE:

This study aims to investigate the changes in antioxidant activity, phenolic compounds and their bioaccessibility in two grape varieties (Cardinal and Dabouki or Sabel) as a result of traditional sun drying and homemade jam processes.

METHODS:

Fresh and dried grapes, as well as jam samples were subjected to a series of spectrophotometric analyses including total phenolics, flavonoids, and antioxidant activity. Individual phenolic compounds were identified and quantified by HPLC-DAD-MS-QTOF. An in vitro gastrointestinal digestion was applied to evaluate the bioaccessibility.

RESULTS:

Both traditional processes led to considerable losses in the levels of some phenolic compounds and their antioxidant activities. However, an increase in the content of other phenolic acids was also observed after processing. Total phenolics, total flavonoids and total antioxidant capacity recovery values of the dialysable fraction of processed samples were higher than those of fresh grapes for both varieties.

CONCLUSIONS:

Traditional raisins and homemade jams could be considered as good sources of natural antioxidants, although a modification of some critical steps that may negatively affect their antioxidant properties is suggested in the light of this study.
The etiology of neonatal pneumonia, complicated by bronchopulmonary dysplasia
Authors: Kushnareva M.V. , Keshishyan E.S. , Balashova E.D.
Published: July 2019

BACKGROUND:

The frequency of bronchopulmonary dysplasia (BPD) in preterm infants with a “ventilator-associated” pneumonia (VAP) ranges between 7 to 50%.

OBJECTIVE:

To investigate the features of the etiological structure of neonatal pneumonia complicated by BPD, and to determine the sensitivity of pathogens to antibiotics.

METHODS:

A retrospective chart review of 194 preterm infants with VAP, birth weight from 780 to 2820 g and gestational age from 27 to 37 weeks was conducted. A microbiological study of washings from the respiratory tract was conducted by standard qualitative and quantitative methods.

RESULTS:

Respiratory tract infections caused by E. coli (with hemolytic properties), Enterococcus spp. (with hemolytic properties), Pseudomonas aeruginosa, Stenotrophomonas maltophilia, various types of mycoplasmas, Staphylococcus aureus, and Candida krusei were found 4– 13 times more frequent in preterm infants with BPD than in preterm infants without BPD and more mature infants with or without this complication. BPD developed 7– 11 times more frequent in preterm infants with prolonged VAP and change in pathogens than in preterm infants with VAP without change of agent. BPD developed 5– 7 times more frequent in preterm infants with the association of pathogens than in preterm infants with a monoinfection. Massive colonization of respiratory tract pathogens by 1– 3 days of life (lg4 colony forming units in 1 ml and above) was an unfavorable prognostic factor for the development of VAP, complicated by BPD.

CONCLUSION:

The reduction in the frequency of BPD is might be possible with timeous and adequate antibacterial therapy of VAP.
Dermatoglifi Narapidana di Palembang
Authors: Mundijo Trisnawati , Rezky Monica
Published: July 2019

Dermatoglifi merupakan salah satu fenotip yang sangat khas dan unik pada manusia. Salah satu kegunaannya sebagai alat bantu dalam diagnosis di kedokteran forensik. Penelitian tentang dermatoglifi pada narapidana masih sangat jarang dan di Palembang belum pernah dilakukan, sehingga penelitian ini dilakukan dengan tujuan untuk mengetahui bagaimanakah dermatoglifi, khususnya pola sidik jari dan Axial Tri Radius Digital (ATD) pada narapidana. Penelitian dilakukan di Lembaga Pemasyarakatan Perempuan di Palembang, dengan sampel diambil secara total sampling sesuai kriteria inklusi. Didapatkan 41 orang narapidana perempuan dengan kejahatan umum dan 51 orang dengan kejahatan khusus. Data dianalisis secara univariat dengan mengidentifikasi pola sidik jari dan sudut Axial Tri Radius Digital (ATD) dari kedua jenis kejahatan. Didapatkan hasil bahwa pola ulnar loop merupakan pola yang paling banyak ditemukan yaitu 62,7% pada kejahatan umum dan 51,2% pada narapidana kejahatan khusus. Untuk sudut ATD dari kedua jenis narapidana di kisaran sudut normal (35°-50°). , sehingga disimpulkan pola sidik jari yang paling banyak pada narapidana perempuan yaitu ulnar loop dengan sudut ATD normal sebesar 35°-50°
PERAN KEPALA MADRASAH DALAM MENINGKATKAN MUTU GURU DI MTS NURUL FALAH TALOK KRESEK KABUPATEN TANGERANG
Authors: Fatoni Malik
Published: July 2019

This study aims to determine how the role of principal In Improving Teacher Quality in Private MTs Nurul Falah Talok Kresek Tangerang District. This research is qualitative with Field Research approach (Field Research). In this research, it is found that the head of madrasah in improving the quality of teachers in private MTs Nurul Falah Talok Kresek Tangerang Regency can be achieved. Achievement and success are based on a number of findings in the research that took place, namely 1). The Head of Madrasah has empowered the effort to improve the quality of teachers by covering various practical and logical work such as teacher competence test, guidance of teaching program and improvement of teacher professionalism, Increase of income and teacher welfare. 2). Madrasah principals undertake various development and fulfillment efforts related to infrastructure and madrasah infrastructure facilities. Another result of this research is that the success of the madrasah head that can support the process of teacher quality improvement can occur due to several factors, among others 1). Madrasah principal can play an important role as a leader with its central power to always move the artery of madrasah life, 2). The head of Madrasah is also able to understand SOP, their duties and functions for the success of madrasah accompanied by a strong attitude towards the subordinates who lead in this case the teacher in his madrasah.

Keywords. Management, Human Resource Development, Madrasah.
MANAJEMEN PERENCANAAN PEMBELAJARAN
Authors: Suryapermana Nana
Published: July 2019

Learning does not just exist and happens in front of our eyes and under the gaze of student’s who wait with anxious hopes, can not, miss understanding, not no, not difficult to accompany the lesson. To destroy the feeling, of course, in the planning of learning teachers should pay attention to the learning system that will bandage all the actions of the process of teaching and learning activities. This is important, because if in the execution of teaching and learning process out and away from the system, then whatever is expected and pursued by teachers in learning activities will only reap failures and suffering and this is the beginning of catastrophe in the world of education.

Keywords. Management, Learning
IMPLEMENTASI PROGRAM BOARDING SCHOOL DALAM PEMBENTUKAN KARAKTER SISWA DI SMA NEGERI CAHAYA MADANI BANTEN BOARDING SCHOOL PANDEGLANG
Authors: Najihaturrohmah Najihaturrohmah
Published: July 2019

This study aims to determine the implementation of boarding school programs in the formation of student characters in State Senior High School of Cahaya Madani Banten Boarding School Pandeglang Banten. The type of this research is qualitative descriptive research. The research data was collected with several techniques, such as observation, interview, and documentation. Triangulation technique is done by means of triangulation method, that is by checking the information result of interview with documentation and observation. The results of the discussion of the implementation of boarding school programs in the formation of student characters include: There is guidance of character education that appear in State Senior High School of Cahaya Madani Banten Boarding School Pandeglang Banten include: 1) Religious, attitude, and behavior; 2) Discipline, actions that demonstrate orderly conduct and abide by various rules and regulations. 3) Honest behavior based on an attempt to make himself or herself a person who can always be trusted in words, actions, and work. 4) Mandiri, 5) Responsibility of the attitude and behavior of a person to carry out his duties and obligations, which he should do, to oneself, society, environment (nature, social and culture), state, and god almighty.

Keywords. Boarding school, character education, religious, discipline
LINGKUNGAN PENDIDIKAN DALAM AL-QUR’AN DAN HADIS
Authors: Hasbullah Hasbullah
Published: July 2019

Educational environment is needed in the education process, because the educational environment serves to support the process of teaching and learning, a comfortable environment and support for the implementation of an education is needed. The environment is distinguished into the biological environment, the non-living natural environment, the artificial environment and the social environment. Education is one of the first obligations for parents. In Islam, the person most responsible for the education of the child is the parent. The family is the "smallest people" who have leaders and members, has a division of work and work, and the rights and obligations of each member. The best exemplary education for children is if both parents are able to connect their child with the example of Rasûlullâh SAW, as uswah of all mankind. A positive school environment is a school environment that provides facilities and motivation for religious education.

Keywords. Environment, Education
MANAJEMEN KELAS DALAM MENINGKATKAN PROSES PEMBELAJARAN
Authors: Nugraha Muldiyana
Published: July 2019

The purpose of this research to describe the planning of classroom management, the implementation of classroom management, supporting and hibiting factors of classroom management to increase learning process, and than the strategy to increase learning process. The research methodology is descriptive qualitative method. The result showed that the planning of classroom management do with prepared and arrange set of equipment and instrumen of study. The implementation of classroom management in the study appled some classroom management principles and some approaches. The supporting and inhibiting factors are physical environment, social emotional and organization condition. The strategy was students condition for already study in the class, learn to concentration, using the right method and variation, interaction in educatif and communicative, and than the students were using media with the teaching was.

Keywords.  Classroom Management, Learning Process
PENGEMBANGAN PROFESIONALISME GURU PADA MTsN 1 SERANG MELALUI PENINGKATAN KOMPETENSI PROFESIONAL DAN PEDAGOGIK
Authors: Mulyani Nani
Published: July 2019

This study aims to determine the development of teacher professionalism in MTsN 1 in Serang Regency through an increase in professional and pedagogical competencies. This research was carried out in the Serang District 1 MTsN. The research methodology uses qualitative studies with a field research approach that attempts to research or make observations and jump directly in the field. Research on the development of teacher professionalism in Serang District 1 Madrasah Tsanawiyah Negeri is not only enough with theoretical studies but it needs direct research to the location studied, known as observation using a systematic approach. While the speakers who can be used as resource persons include the head of The Madrasa and all Madrasa teachers. Based on the results of the research the development of teacher professionalism through competency and pedagogical improvement can be done in a way, namely: First: Pedagogic Ability; Ability to Understand Students, Ability to Design Learning, Ability to Implement Learning Processes, Ability to Assess Processes and Results, and Ability to Develop Potential Students. Second: Professional Ability; can be described by the ability to master the field of study seen from the educational background of teachers who have academic qualifications and teaching teachers in accordance with their expertise and majors, and have the ability and understanding of students, the ability to master educational learning through the ability to understand the types of subjects, organizing the subjects and utilize learning resources.Keywords: teacher professionalism, professionalism, pedagogy, teacher performance
IMPLEMENTASI PEMBENTUKAN KARAKTER MELALUI PROGRAM BOARDING SCHOOL SMP ARDANIAH KOTA SERANG
Authors: Magesaharani Siti , Ibrohim Busthomi
Published: July 2019

The purpose of this research is to analyse the formation of character in students of Junior High School Ardaniah Boarding School Serang Banten. Research methods using qualitative descriptive method. Data collection techniques using observation, interviews, and documentation. Triangulation was done by way of rechecking the information interview results with the results of observation and documentation. The research found that the formation of character in the Boarding School Program Junior Ardaniah is done through: 1) academic activities, either intrasekolah or ekstrasekolah; 2) religious activities, such as: Islamic studies, the study of the book of yellow, muhadhoroh, memorizing the Qur'an, Qur'an tahfidz and Lughotul al-Ta'lim al Arabia; 3) activity skills, such as: activities The cultivation of Plants through tissue culture of language skills, and information and Communication Technology skills. The characters are observed is 1) religious, attitudes, and behavior; 2) disciplines3) honest. 4) independent, 5) responsibility towards themselves, society, environment, country and God Almighty.

Keywords: Boarding school, character education, religious discipline
The research of tolerance of solution for intrauterus application “Yodozol”
Authors: Sachuk R. M. , Katsaraba O. A. , Stravsky Ya. S. , Zhigalyuk S. V.
Published: July 2019

Complex clinical trials have been carried out in order to study the tolerance and detail of the effect on the morpho-functional state of the organism of target animals of the new development of PE “Biopharm” and the Experimental Station of Epizootology IVM NAAS – solution for intrauterus use in the form of aerosol “Yodozol”, which will help predict the appearance of side effects from drug and prevent it. Methods of evaluation of a medicinal product for clinical trials, including for determining tolerance limits, which were used, included: the determination of the general clinical state of the organism, the study of hematological and biochemical parameters of blood, the control of the age of their first calving and service period, as well as statistical (calculation of average values and error of experimental data). “Yodozol” is a light yellow liquid, 1 ml of which contains 5 mg of iodine and 10 mg of potassium iodide. The drug is used for the prophylaxis and treatment of postpartum intrauterine infections in cows, pigs, sheep and goats (endometritis, pyrometers, cervicitis, vaginitis, delayed digestion caused by microorganisms sensitive to iodine), after giving rhombus, cesarean section and postpartum sanitation of the uterus. Medical product possesses antimicrobial, anti-inflammatory and analgesic actions, improves proliferative processes of genital organs, reduces the time of recovery of animals. The drug is used in accordance with the guidelines, after which livestock products are used without restriction. It has been established that the new medicinal product “Yodozol” with three times intrauterine application of cattle at intervals of 48 hours in doses that 2–10 times exceeds the recommended therapeutic, is tolerant. The excess amount of the drug does not cause significant side effects when injected into the uterus. There was no negative influence on the general clinical condition of cows and changes in the morpho-functional state of their organism. Three animals had an increase in the volume of the uterus, omission of horns and the body of the uterus. However, this is a normal individual physiological local reaction of the body to the introduction of an increased amount of foreign matter, which does not affect the general physiological state of animals. The volume and physiological placement of the uterus independently came to normal after the discontinuation of the drug. In all experimental animals exposed to different doses of the iodosol drug, the age of their first calving was from 29.0 ± 1.87 to 33.7 ± 2.27 months, the service period from 76.3 ± 2.27 to 81.0 ± 0.71 days, fluctuating within the limits of physiological norms. All conducted studies of the tolerance of the solution for intrauterine application “Yodozol” were included in the registration materials of the medicinal product.
Ecological and epizootic roles of Golden jackal, genus Canis aureus in the Northwest of Black Sea coast
Authors: Nakonechnyi I. V. , Perots’ka L. V. , Pyvovarova I. V. , Chornyi V. A.
Published: July 2019

Penetration of jackal, typical representative of Asia Minor-Balkan group, genus Canis aureus into the territory of the Northwest Black Sea coast - has become a rather unexpected phenomenon and led to environmental, zoogeographical and epizootic issues. The last one may lead to the development of potentially dangerous epizootic processes, the assessment of the threat and possible consequences require systematic researches. The purpose of this work was to study the ecological and epizootic role of Canis aureus in the territory of the Northwest Black Sea coast. The investigations concerning epizootic status of jackal were carried out during 2014–2018 in the territory of Odesa and Mykolayiv Regions with means of laboratory control samples of the materials which were selected and taken from hunters. The results of researches have shown that there is a complete, self-regulating and rather dense population of C. aureus in this region, it does not lose the rate of intensive reproduction and has a clearly expressed western line of genus penetration. In the process of migratory settlement, jackal demonstrates clear and static dependences on humidified and hydro morphed landscapes. When the bodies of animals were observed, we could find the presence of ticks and several types of fleas that could act as a biological transmission objects in the circles of spontaneous circulation of naturally occurring zoonotic pathogens, ensuring their inter-species migration and short-term reservation. According to the results of laboratory examinations of 9 samples of jackals’ blood serum, the presence of antibodies to the causative agent of erysipelas was determined in 5 (55.5%) cases. In response to a single brucellosis antigen The specific antibodies were not found in the reaction with single brucellosis antigen. The investigations on the presence of leptospirosis were carried out with test strains of 9 serogroups. Specific anti-lepidopteran antibodies were found in all investigated serum samples. The predominance of antibodies to the Grippotyphosa, Hebdomadis, Sejroe, Bataviae serogroups, mice field rodents are their host, indicates the trophic nature of antigenic contacts. The new species for Ukraine – jackal Cainis aureus carries a significant potential epizootic threat as a host and carrier of pathogens natural-focal zoonotic infections and invasions, the most dangerous among them is rabies.
The influence of prophylactic biopreparations on preservation and microbiocenosis of chickens
Authors: Kucheruk M. D. , Zasekin D. A.
Published: July 2019

The cultivation of organic birds is an important stage in ensuring the population, in particular children, a source of quality and easily digestible protein. The use of antibiotics with a prophylactic purpose in organic livestock is prohibited at the legislative level. Therefore, this new direction in agriculture requires professional scientific support and effective natural prophylaxis as an alternative to antibiotics. The research was conducted in a certified organic poultry farm. The purpose of the production trial of the probiotic and the new postbiotic drug on chickens was to compare their effectiveness with respect to the productivity and consistency of the poultry. The results were compared with the data of the control group of chickens and experimental groups among themselves. In addition, there was a link between the performance of chickens with the functional state of intestinal microbiocenosis and the corrective effect of these drugs. The expressed prophylactic effect of the tested drugs on the best of 20–22% preservation of chickens, as well as on higher body weight gain was established. The death of the control group chickens was due to dysbiosis of digestion with the domination of E. coli in the intestine. The study of intestinal microbiocenosis showed significantly higher concentrations of lactobacillus in the chickens of both experimental groups compared with the control group. Due to the competitive substitution of lactobacilli, the amount of E. coli in the intestines of chickens in experimental groups was reduced, where the test drugs were used. Excessive E. coli in the intestines of the control group chickens could provoke inflammation in the intestine and the development of clinical manifestations of colibacillosis. As a consequence – recorded a high percentage of deaths of chickens in this group. Thus, correction of microendocology of poultry intestines may be carried out by prophylactic preparations based on living representatives of symbiotic microflora (probiotics) or compositions of their useful metabolites (postbiotics). Such a correction occurs naturally, without violating the traditional mechanisms of interaction within the microbiological pool.