bluuebunny/crossref_metadata_2025 huggingface dataset:
Sustainable or a Butterfly Effect in Global Tourism? Nexus of Pandemic Fatigue, COVID-19-Branded Destination Safety, Travel Stimulus Incentives, and Post-Pandemic Revenge Travel
Authors: Zaman Umer , Raza Syed Hassan , Abbasi Saba , Aktan Murat , Farías Pablo
Published: November 2021

Revenge travel has globally emerged as a dominant touristic behavior, signaling a rapid return of global tourism, but with a greater temptation for spending more and staying longer. Despite the expanding focus on global sustainable tourism, there is a lack of empirical evidence on the potential factors that build momentum for revenge travel. The aim of the present study was to develop and test a conceptualized model of revenge travel under the influence of pandemic fatigue, COVID-19-branded destination safety, and travel stimulus incentives. Drawing on the study data of international expats (N = 422) and using covariance-based structural equation modeling (CB-SEM), the findings provide new evidence that revenge travel is significantly and positively influenced by pandemic fatigue. Interestingly, the empirical findings also support two positive moderations, highlighting that COVID-19-branded destination safety (CBDS) and travel stimulus incentives (TI) can significantly increase the impact of pandemic fatigue (PF) on revenge travel (RT). Based on prominent theories (i.e., theory of planned behavior, protection motivation theory, and incentive theory of motivation) and newly developed scales (i.e., RT, CBDS, and TI), the study highlights the dynamics of revenge travel as it sets the stage for global tourism to rebound stronger than ever. The implications include new challenges and ways forward through revenge travel as a stepping stone for global sustainable tourism.
On Ulam Stability of Functional Equations in 2-Normed Spaces—A Survey
Authors: Bahyrycz Anna , Brzdęk Janusz , El-hady El-sayed , Leśniak Zbigniew
Published: November 2021

The theory of Ulam stability was initiated by a problem raised in 1940 by S. Ulam and concerning approximate solutions to the equation of homomorphism in groups. It is somehow connected to various other areas of investigation such as, e.g., optimization and approximation theory. Its main issue is the error that we make when replacing functions satisfying the equation approximately with exact solutions of the equation. This article is a survey of the published so far results on Ulam stability for functional equations in 2-normed spaces. We present and discuss them, pointing to the various pitfalls they contain and showing possible simple generalizations. In this way, in particular, we demonstrate that the easily noticeable symmetry between them and the analogous results obtained for the classical metric or normed spaces is in fact only apparent.
Completeness of b−Metric Spaces and Best Proximity Points of Nonself Quasi-Contractions
Authors: Khan Arshad Ali , Ali Basit
Published: November 2021

The aims of this article are twofold. One is to prove some results regarding the existence of best proximity points of multivalued non-self quasi-contractions of b−metric spaces (which are symmetric spaces) and the other is to obtain a characterization of completeness of b−metric spaces via the existence of best proximity points of non-self quasi-contractions. Further, we pose some questions related to the findings in the paper. An example is provided to illustrate the main result. The results obtained herein improve some well known results in the literature.
ChemSkin Reference Chemical Database for the Development of an In Vitro Skin Irritation Test
Authors: Han Juhee , Lee Ga-Young , Bae Green , Kang Mi-Jeong , Lim Kyung-Min
Published: November 2021

Since the animal test ban on cosmetics in the EU in 2013, alternative in vitro safety tests have been actively researched to replace in vivo animal tests. For the development and evaluation of a new test method, reference chemicals with quality in vivo data are essential to assess the predictive capacity and applicability domain. Here, we compiled a reference chemical database (ChemSkin DB) for the development and evaluation of new in vitro skin irritation tests. The first candidates were selected from 317 chemicals (source data n = 1567) searched from the literature from the last 20 years, including previous validation study reports, ECETOC, and published papers. Chemicals showing inconsistent classification or those that were commercially unavailable, difficult or dangerous to handle, prohibitively expensive, or without quality in vivo or in vitro data were removed, leaving a total of 100 chemicals. Supporting references, in vivo Draize scores, UN GHS/EU CLP classifications and commercial sources were compiled. Test results produced by the approved methods of OECD Test No. 439 were included and compared using the classification table, scatter plot, and Pearson correlation analysis to identify the false predictions and differences between in vitro skin irritation tests. These results may provide an insight into the future development of new in vitro skin irritation tests.
Cosmetic Applications of Bee Venom
Authors: El-Wahed Aida A. Abd , Khalifa Shaden A. M. , Elashal Mohamed H. , Musharraf Syed G. , Saeed Aamer , Khatib Alfi , Tahir Haroon Elrasheid , Zou Xiaobo , Naggar Yahya Al , Mehmood Arshad , Wang Kai , El-Seedi Hesham R.
Published: November 2021

Bee venom (BV) is a typical toxin secreted by stingers of honeybee workers. BV and BV therapy have long been attractive to different cultures, with extensive studies during recent decades. Nowadays, BV is applied to combat several skin diseases, such as atopic dermatitis, acne vulgaris, alopecia, vitiligo, and psoriasis. BV is used extensively in topical preparations as cosmetics and used as dressing for wound healing, as well as in facemasks. Nevertheless, the safety of BV as a therapeutic choice has always been a concern due to the immune system reaction in some people due to BV use. The documented unfavorable impact is explained by the fact that the skin reactions to BV might expand to excessive immunological responses, including anaphylaxis, that typically resolve over numerous days. This review aims to address bee venom therapeutic uses in skin cosmetics.
How COVID-19 Exposed Water Supply Fragility in Florida, USA
Authors: Lusk Mary G. , Krimsky Lisa S. , Taylor Nicholas
Published: November 2021

Healthcare demand for liquid oxygen during the COVID-19 pandemic limited the availability of oxygen needed for ozone disinfection of drinking water in several urban areas of Florida. While the situation reduced the state’s capacity to provide normal drinking water treatment for millions of people, calls for water conservation during the emergency period resulted in virtually no change in water consumption. Here, we point out that 38–40% of the potable water produced by one of the major utilities in Florida is not used for drinking water but instead is used for outdoor landscape irrigation. This suggests that emergency-level calls for reduced water use could have been made if outdoor irrigation was limited, but we present data showing that there was little change in public behavior, and the state was unable to meet necessary water use reductions during the emergency. This inability to meet short-term emergency water conservation needs foretells a long-term lack of resilience against other global change scenarios and suggests that much work is still needed to build resilience into Florida’s water future. We conclude this Viewpoint paper by calling for more urgent sociohydrological research to understand the coupled human-natural drivers of how water supplies respond to global change.
Identification of a B-Cell Epitope in the VP3 Protein of Senecavirus A
Authors: Chen Mi , Chen Lulu , Wang Jing , Mou Chunxiao , Chen Zhenhai
Published: November 2021

Senecavirus A (SVA) is a member of the genus Senecavirus of the family Picornaviridae. SVA-associated vesicular disease (SAVD) outbreaks have been extensively reported since 2014–2015. Characteristic symptoms include vesicular lesions on the snout and feet as well as lameness in adult pigs and even death in piglets. The capsid protein VP3, a structural protein of SVA, is involved in viral replication and genome packaging. Here, we developed and characterized a mouse monoclonal antibody (mAb) 3E9 against VP3. A motif 192GWFSLHKLTK201 was identified as the linear B-cell epitope recognized by mAb 3E9 by using a panel of GFP-tagged epitope polypeptides. Sequence alignments show that 192GWFSLHKLTK201 was highly conserved in all SVA strains. Subsequently, alanine (A)-scanning mutagenesis indicated that W193, F194, L196, and H197 were the critical residues recognized by mAb 3E9. Further investigation with indirect immunofluorescence assay indicated that the VP3 protein was present in the cytoplasm during SVA replication. In addition, the mAb 3E9 specifically immunoprecipitated the VP3 protein from SVA-infected cells. Taken together, our results indicate that mAb 3E9 could be a powerful tool to work on the function of the VP3 protein during virus infection.
An Overview of Recent Insights into the Response of TLR to SARS-CoV-2 Infection and the Potential of TLR Agonists as SARS-CoV-2 Vaccine Adjuvants
Authors: Kayesh Mohammad Enamul Hoque , Kohara Michinori , Tsukiyama-Kohara Kyoko
Published: November 2021

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to coronavirus disease (COVID-19), a global health pandemic causing millions of deaths worldwide. However, the immunopathogenesis of COVID-19, particularly the interaction between SARS-CoV-2 and host innate immunity, remains unclear. The innate immune system acts as the first line of host defense, which is critical for the initial detection of invading pathogens and the activation and shaping of adaptive immunity. Toll-like receptors (TLRs) are key sensors of innate immunity that recognize pathogen-associated molecular patterns and activate downstream signaling for pro-inflammatory cytokine and chemokine production. However, TLRs may also act as a double-edged sword, and dysregulated TLR responses may enhance immune-mediated pathology, instead of providing protection. Therefore, a proper understanding of the interaction between TLRs and SARS-CoV-2 is of great importance for devising therapeutic and preventive strategies. The use of TLR agonists as vaccine adjuvants for human disease is a promising approach that could be applied in the investigation of COVID-19 vaccines. In this review, we discuss the recent progress in our understanding of host innate immune responses in SARS-CoV-2 infection, with particular focus on TLR response. In addition, we discuss the use of TLR agonists as vaccine adjuvants in enhancing the efficacy of COVID-19 vaccine.
A Review of the Implementation Status of and National Plans on HPV Vaccination in 17 Middle-Income Countries of the WHO Western Pacific Region
Authors: Haruyama Rei , Okawa Sumiyo , Akaba Hiroki , Obara Hiromi , Fujita Noriko
Published: November 2021

The World Health Organization’s Western Pacific Region is responsible for one-fourth of the global cervical cancer burden, and nearly 90% of that burden is concentrated in middle-income countries (MICs). Applying a conceptual model of implementation of population-based interventions, we synthesized the current implementation status of human papillomavirus (HPV) vaccination and national plans that form the basis of its implementation in 17 MICs. We gathered information from a range of governmental documents, published studies, and global databases. For all available national cancer-related plans and immunization plans, we examined the description of HPV vaccination. We found that, as of July 2021, only four countries (24%) had a mature HPV vaccination program with a high first-dose coverage; three (18%) had introduced HPV vaccination, but needed further efforts to scale it up, seven (41%) had not been able to introduce it after conducting demonstration projects, and three (18%) did not have any experience in HPV vaccination. In the national plans, most of the countries recognized the importance of HPV vaccination, but only 10 (59%) provided an implementation strategy on how it would be introduced or scaled up. Countries with a mature program were more likely to have their implementation strategy detailed in their national cancer control plan. Successful implementation of HPV vaccination requires overcoming known challenges and having a clear national plan. Positioning HPV vaccination clearly in the overall national cancer control plan may be key to accelerating its nationwide implementation.
Enhanced Asymptomatic Systemic Infection Caused by Plesiomonas shigelloides in a Captive Gray Wolf (Canis lupus)
Authors: Kim Kyoo-Tae , Lee Haeseung , Kwak Dongmi
Published: November 2021

A 7-year-old male gray wolf was found dead at a zoo during exhibition. To determine the cause of death, histological and gross necropsy diagnoses and a molecular analysis were performed. The gross necropsy revealed a swollen abdomen, hemorrhagic exudates around the mouth, splenomegaly, a discolored liver, a congested kidney, hemorrhagic ascites, and dark gray-colored membranes and air bubbles in the fundus of the stomach. Rod-shaped bacteria were found in the liver parenchyma and hemorrhagic ascites using Giemsa staining. The nucleotide sequencing of the cultured bacteria identified the causative agent as Plesiomonas shigelloides, which is rarely responsible for systemic infections. This study describes a rare case and the first reported systemic gastrointestinal infection due to P. shigelloides in a zoo animal.
Application of Geostatistical Tools to the Geochemical Characterization of the Peloritani Mts (Sicily, Italy) Aquifers
Authors: Cangemi Marianna , Censi Valentina , Madonia Paolo , Favara Rocco
Published: November 2021

Sources of groundwater contaminants in inhabited areas, located in complex geo-tectonic contexts, are often deeply interlocked, thus, making the discrimination between anthropic and natural origins difficult. In this study, we investigate the Peloritani Mountain aquifers (Sicily, Italy), using the combination of probability plots with concentration contour maps to retrieve an overall view of the groundwater geo-chemistry with a special focus on the flux of heavy metals. In particular, we present a methodology for integrating spatial data with very different levels of precision, acquired before and during the “geomatic era”. Our results depict a complex geochemical layout driven by a geo-puzzle of rocks with very different lithological natures, hydraulically connected by a dense tectonic network that is also responsible for the mixing of deep hydrothermal fluids with the meteoric recharge. Moreover, a double source, geogenic or anthropogenic, was individuated for many chemicals delivered to groundwater bodies. The concentration contour maps, based on the different data groups identified by the probability plots, fit the coherency and congruency criteria with the distribution of both rock matrices and anthropogenic sources for chemicals, indicating the success of our geostatistical approach.
Three New Species of Placoneis Mereschkowsky (Bacillariophyceae: Cymbellales) with Comments on Cryptic Diversity in the P. elginensis—Group
Authors: Kezlya Elena , Glushchenko Anton , Maltsev Yevhen , Gusev Evgeniy , Genkal Sergey , Kociolek John Patrick , Kulikovskiy Maxim
Published: November 2021

Using genetic markers 18S V4 rDNA and rbcL and morphological investigation of the diatom genus Placoneis, we described three new species. The new species, Placoneis baikaloelginensis sp. nov., Placoneis subundulata sp. nov., Placoneis neohambergii sp. nov. were isolated from Russia (Lake Baikal) and Vietnam (waterbodies of Cát Tiên National Park (Đồng Nai Province) and Khánh Hòa Province). We examine relationships within the Cymbellales and show that the genera Placoneis, Paraplaconeis and Geissleria are phylogenetically independent. We discuss the importance of careful identification of strains used for phylogenetic analysis and we show the history of identification of several different Placoneis elginensis strains. After careful identification of Placoneis elginensis vouchers, we found that we have a few independent species. The question of cryptic or pseudocryptic species in this context is discussed.
Nonlinear Influence Model of Built Environment of Residential Area on Electric Vehicle Miles Traveled
Authors: Hu Xinghua , Cao Yanshi , Peng Tao , Gao Runze , Dai Gao
Published: November 2021

In this study, gradient boosting decision tree (GBDT) and ordinary least squares (OLS) models were constructed to systematically ascertain the influencing factors and electric vehicle (EV) use action laws from the perspective of travelers. The use intensity of EVs was represented by electric vehicle miles traveled (eVMT); variables such as the charging time, travel preference, and annual income were used to describe the travel characteristics. Seven variables, including distance to the nearest business district, road density, public transport service level, and land use mix were extracted from different dimensions to describe the built environment, explore the influence of the travel behavior mode and built environment on EV use. From the eVMT survey data, points of interest (POI) data, urban road network data, and other heterogeneous data from Chongqing, an empirical analysis of EV usage intensity was conducted. The results indicated that the deviation of the GBDT model (9.62%) was 11.72% lower than that of the OLS model (21.34%). The charging time was the most significant factor influencing the service intensity of EVs (18.37%). The charging pile density (15.24%), EV preference (11.52%), and distance to the nearest business district (10.28%) also exerted a significant influence.
STATISTICAL STUDY OF THE STATE AND DEVELOPMENT OF FOREIGN TRADE OF UKRAINE
Authors: MYLASHKO Olha
Published: November 2021

The directions of statistical analysis of the country’s foreign trade processes are considered in the article. Possibilities of statistical methods for studying the state and the main trends that have developed in this area are highlighted. The conclusions about the intensity of the dynamics of the trade balance indicators are generalized. The processes of the outstripping development of imports over exports are highlighted. The dynamics of the balance of export-import operations is analyzed and trends of its deterioration are demonstrated. The degree of coverage of imports by exports and the processes of formation of the trade balance deficit are investigated in time. The directions of development of characteristics of the balance of foreign trade operations are studied. High levels of export and import dependence of the country have been demonstrated, which leads to vulnerability to external shocks and instability in the world. The results of the analysis of the structure and structural shifts in the trade of Ukraine with the countries of the Visegrad Four are presented. The emphasis is made on the prospects of interrelations with this group of countries from the point of view of using their experience in preparing for accession to the EU. The article demonstrates more intensive changes in the geographical structure of exports than imports and highlights the tendencies towards an increase in the role of Poland and a decrease in Hungary in the export-import operations of the Visegrad Four with Ukraine. The processes of changing the terms of trade have been investigated in terms of changes in export and import prices and in terms of changes in the physical volume of exports and imports on the example of a group of dairy products, which are widely represented among both export and import goods of Ukraine. The index method was used to analyze the absolute and relative impact of changes in prices and the physical volume of exports and imports of a number of dairy products on the value of exports and imports. Changes in the terms of trade are highlighted by constructing quantitative and price indices of the terms of trade. It was clarified that it was the sharp reduction in the physical volume of exports that contributed to the decrease in foreign exchange earnings from the export of dairy products. The necessity of measures to promote domestic goods abroad, primarily to European countries, has been substantiated. The research results can be used in foreign trade policy at the macro level.
THE POWER OF NO-LAG TECHNICAL INDICATORS IN ALGORITHMIC TRADING
Authors: BUTIN Frédéric
Published: November 2021

In the framework of technical analysis for algorithmic trading we introduce an original approach to classical technical indicators. For this, we consider technical indicators as bounded operators: this more abstract, but also more algorithmic view enables us to define in a very simple way the no-lag versions of these tools. Delay in response is indeed a major drawback of many classical technical indicators used in algorithmic trading, which often leads to a wrong information. On the contrary, with the no-lag versions of the indicators that we study here, we get better information that is closer to the instantaneous values of the securities, hence a better expected rate of return of the trading system in which they occur. After having recalled the definitions of weighted and exponential averages as bounded operators, we prove that the lag possesses a fundamental property that is very useful to create no-lag versions of technical indicators. This being done, we apply our results to a basic trading system and test it on the S&P 500 index, in order to compare the classical Elder’s impulse system with its no-lag version and the so-called Nyquist-Elder’s impulse system: we observe on this example that the no-lag versions of indicators lead to much more profitable systems. More precisely, the Nyquist-Elder’s impulse system is much better than the Elder’s impulse system without lag, which is itself better than the classical impulse system: the information given by Nyquist-Elder’s impulse system is indeed closer to the instantaneous value of the S&P 500 index since it has less delay than the classical impulse system: Nyquist-Elder’s impulse system is even the closest to the instantaneous value among the three ones. We eventually compare the profit/loss of four portfolios (a portfolio that replicates S&P 500 index, and one for every of the three impulse systems) in order to better understand the time dynamics of our three Elder’s impulse systems. As far as we can see, we also notice a lower draw-down for the portfolio associated to the system using the Nyquist-Elder’s impulse system than for the other ones, and this portfolio seems to be more resistant to bearish periods.
From Lives to Discurso in the biographies of Thomas More: Roper, Harpsfield and Herrera
Authors: García García Luciano
Published: November 2021

This article compares the books about the Lifes of Thomas More written by Roper and Harpsfield and the work Tomás Moro by Fernando de Herrera. The comparison is taken as a case in point of the divergent early development of the biographical genre in England and in Spain. The three texts were written by Catholic humanists, but under different contexts, which produced different kinds of text. Roper’s and Harpsfield’s Catholicism, marked by a close contact with the Morean tradition, the English form of Counter-Reformation under Mary, and the Elizabethan reversion to Protestantism, makes them drift towards an early form of modern biography. Fernando de Herrera, however, sets out to write his text from the background of the Spanish Counter-Reformation and a different discursive and textual conception of life writing.
Mending “the injurie of oblivion”: “Englishing” Chaucer and Barbour in early printed editions
Authors: Henk Antony
Published: November 2021

This article examines the editorial choices made in Edinburgh printer Andro Hart’s 1616 edition of John Barbour’s Brus. Comparison of the 1616 Hart edition with Thomas Speght’s 1602 Chaucer edition displays similar concerns with preserving accessibility to historical texts despite significant language changes in both Older Scots and English, noting shared employment of assistive paratextual apparati. Linguistic assessment comparing Hart and Speght’s editions to their parent texts demonstrates how both editors modernize language to improve reader accessibility while preserving archaic qualities and metricality. Contextualization of the declining prestige of Older Scots during the sixteenth and seventeenth centuries further clarifies this assessment. Hart’s edition portrays both a genesis of mutual intelligibility between Scots and English, and a coda for Older Scots as a literary prestige tongue.
A ballad of treason for Queen Mary I’s accession
Authors: Schutte Valerie
Published: November 2021

A ninuectyue agaynst Treason is a ballad that was printed upon Queen Mary I’s accession. It is comprised of fourteen stanzas; the first ten each have seven lines, and the last four are only four lines each. The ballad is not so much celebratory of the new Queen Mary, but a lesson or warning about the dangers of acting against a Tudor monarch.
Optimal control of the digital twin of the enterprise.
Authors:   LLC «Sistemy Upravleniya», Masaev S.N.
Published: November 2021

The enterprise is presented as a digital twin of interrelated production processes, support processes and administrative processes. A semantic indicator for a general assessment of the state of the system at different points in time is given. The semantic indicator is applied to assess the optimal control by Kalman filter. The obtained estimates of optimal control make it possible to take into account the resources consumed by the processes in the past periods. The obtained optimal control can be used with other control methods through control and observation matrices. Estimates of the optimal ratio of values are obtained: the amount of the resource in the system, the method of attracting the resource, the execution time of the method, the computational complexity of the method.
Method for constructing a territorial-oriented normative model for estimation of the life quality taking into account the territories specification (in the case of Krasnoyarsk region).
Authors:   ICM SB RAS, Penkova T.G. , Metus A.M. , Nicheporchuk V.V. , Nozhenkov A.I.
Published: November 2021

This paper presents a method of constructing the territorially oriented normative model for calculating the rating assessments of the life quality and describing the “desired” level of life quality taking into account the individual character- istics of the territories. The proposed method provides the formation of assessment criteria, principles of generalization of assessments, and scales of their interpretation by considering the socio-economic and physical-geographical features of the territories. Constructing the normative model is carried out in the case of the Krasnoyarsk region.
Analysis of the new central bank of the russia requirements for operational risk management to ensure information security.
Authors:   Financial University under the Government of the Russian Federation, Borovskaya O.E. , Larionova S.L.
Published: November 2021

On October 1, 2020, the new Regulation of the Central Bank of the Russian Federation No. 716-P “On requirements for the Operational risk Management System in a Credit institution and a banking group” came into force. The article is devoted to the analysis of the requirements of the regulation that must be taken into account before January 1, 2022 within the information security management system in connection with the use of a risk-oriented approach to the allocation of resources of a financial organization.
Method for monitoring and diagnosing local incidents with the potential for protest mobilization.
Authors:   Saint-Petersburg Federal Research Center, Russian Academy of Sciences, Vitkova L.A. , Zelichenok I.U.
Published: November 2021

The article presents a methodology for monitoring and diagnosing local incidents with the potential for protest activity, which consists of four main steps and five related modules. The method differs from its analogues in that it takes into account the textual features of the network strategies of communication participants, hierarchical relationships between information objects, and attributes of audience activity in social networks. At the same time, the technique provides diagnostics of a local incident and detection of the beginning of its artificial mediatization. The article also demonstrates the results of experimental studies.
Self-Efficacy and Problem-Solving among College Students during COVID-19 Pandemic
Authors: Fatmawati F , Maryam Siti
Published: November 2021

During the COVID-19 pandemic and the implementation of online learning system, the pressure faced by students is far greater than before. The existence of the problems certainly requires students to be able to survive and find the right way out. Problem-solving is an indication that shows how strong a person is in facing a difficulty. Students with high self-efficacy believe that they are able to do something to change the problems around them. Therefore, this study aimed to measure the association between self-efficacy and problem-solving among college students during COVID-19 pandemic. The number of participant recruited through accidental random technique was 150 college students in the city of Banda Aceh. General Self-Efficacy Scale was employed in order to obtain the data on self-efficacy, whereas problem-solving ability was calculated through Solving Problem Survey. Pearson Correlation was used to analyze the data and it showed a positive relationship between those two variables. Besides, the analysis also displayed a significance value of 0.000 (p<0.05). This indicated that the hypothesis was accepted –there was a very significant relationship between self-efficacy and problem-solving among college students during COVID-19 pandemic.
JUDICIAL REVIEW SATU ATAP DI MAHKAMAH KONSTITUSI SEBAGAI REFLEKSI TERHADAP PROBLEMATIKA DAN TANTANGAN KEKUASAAN KEHAKIMAN DI INDONESIA
Authors: Ali Hofi Moh.
Published: November 2021

Judicial review merupakan suatu upaya hukum agar dapat keluar dari peroalan regulasi yang dihasilkan pembentuk uu dengan kualitas rendah.  namun demikian, penyelenggaraan judicial review pada praktiknya selama ini dapat memunculkan suatu persoalan hukum. Penyebabnya di antaranya adalah pembagian kewenangan dalam praktik judicial review oleh MK dan MA untuk melakukan judicial review. Disamping hal di atas, beberapa alasan pengujian satu atap di Mahkamah Konstitusi didasari  beberapa alasan, di antaranya mengurungi beban menumpuk di Mahkamah Agung mengingat MA tidak hanya sekedar menguji regulasi dibawah uu, kasasi, peninjauan kembali kasus pidana dan perdata serta TUN juga menjadi bagian dari kewenangan MA yang tidak terpisahkan, kepastian hukum serta keadilan bagi masyarakat, efisiensi dan efektifitas dapat diwujudkan bila dilakukan dalam satu atap di MK. Praktik judicial review di Mahkamah Konstitusi sangat terbuka bila di bandingkan MA. Karenanya judicial review satu di MK Urgent untuk dilaksanakan. Tulisan ini mengkaji dengan konkrit persoalan dualisme judicial review dalam perspektif negara hukum serta ugensi judicial review satu pintu di MK sebagai solusi atas problematika di atas.
Effect of Ta Content on Microstructure and Phase Transformation Temperatures of Ti75.5-Nb25.5 (%at.) Alloy
Authors: MOHAMMED Safar , DAĞDELEN Fethi , QADER Ibrahim Nazem
Published: November 2021

β-titanium shape memory alloys are used as shape memory-based biomedical applications and superelastic materials because they are made up of non-toxic components. Also, their behaviors are more semilar with that of human bone and dental biological tissues, such as biocompatibility, superior corrosion resistance, low density, and low modulus of elasticity. In the current study, the effect of Ta additive on the physical properties of Ti-Nb alloy has been investigated. Ti-Nb-Ta alloy samples were produced such that the Tantalum (Ta) element was substituted instead of Niobium (Nb), and the induction arc melting was used to melting the mixed powders. To investigate the crystal structure, microstructure, and phase transformation temperatures of all samples, the X-Ray Diffraction (XRD), Scanning Electron Microscopic (SEM), and Diffraction Scanning Calorimetry (DSC) measurements have been used. Both β-rich and α peaks were observed in the XRD and SEM measurements. Also, the DSC results revealed that the Ti-Nb-Ta alloys have only austenite transformation temperatures and their phase austenite phase transformation were decreased by the effect of Ta additive, additionally, the enthalpy change in〖 E〗_3 sample ( Ti_75.5 Nb_22.5 Ta_2 (%at)) has the highest value, while E_4 sample ( Ti_75.5 Nb_21.5 Ta_3 (%at)) has the lowest respective value.
Robust Reference Tracking and Load Rejection on Non-Linear System Using Controllers
Authors: G.S Renjini , THANGAVELUSAMY Deepa
Published: November 2021

DC-DC converters form a class of highly nonlinear systems and are widely used in most practical applications. Positive Output Elementary Luo Converter (POELC) is a fourth-order converter used to regulate dc voltages in low power applications with varying input voltage and load conditions. POELC is employed to regulate dc voltages for sensitive load applications like SMPS, powering hard disks etc. The control of higher-order converters is always a challenging task due to the highly nonlinear nature of these converters. Hence the development of an optimal controller for POELC is proposed in this paper. The proposed control methods are investigated for transient and steady-state performances considering practical operating conditions. The controllers are designed, simulated and the performance of POELC with various controllers is evaluated in the MATLAB/Simulink environment. The PI controller exhibits better performance in the linear region whereas, in the nonlinear region, due to time variance and switching nature. To minimize the sensitivity to external disturbances and to improve the stability margins, an LQR is designed to regulate the output of POELC. The result shows that a well-designed LQR feedback can stabilize the system and enhances its performance in terms of Integral Absolute Error (IAE), Integral Square Error (ISE). Certain case studies are discussed concerning practical applications.
Toward the Shari'ah Paradigm of Islamic Economics
Authors: Arif Muhammad
Published: November 2021

I. INTRODUCTION -THE MAJOR CRITICS OFISLAMIC ECONOMICS: This paper attempts to respond to the critics who, on various grounds, oppose the development of Islamic economics. The author feels that a scientific response to these critics is the responsibility of the Islamic economists. It is believed that such a response would be educational for the critics and their followers. It would enable them not only to understand the scientific nature of Islamic economics but would also allow them to appreciate that the development of the Shari'ah paradigm ofislamic economics is, in fact, the beginningofascientific revolution in economics. Given the bases of their arguments, these critics of Islamic economics can be classified into the following three schools of thought.

1) The Adjusted Capitalism School:

According to this school the fundamental principles of the Islamic economic system are the same as those of capitalism. In support of this assertion they point out that like capitalism, Islam also allows the right to private property, free enterprise, and market economy. They, however, acknowledge that certain adjustments need to be made in capitalism to bring it in conformity with Islamic principles. They hold that these adjustments should be made according to Islam's distinction between Haram and Halal, and Islam's teachings in financial and fiscal areas; namely, riba and zakat. According to this school, if these areas of capitalism are adjusted according to Islamic requirements, then the adjusted form of capitalism will be nothing but the Islamic economic system. Thus this school holds that the conventional economic theory, with only a few adjustments, is fully capable of generating the Islamic economic system. Hence, they see no scientific justification for the development of Islamic economics toward the creation and establish­ment of an Islamic economic system ...
W.D. Muhammad
Authors: Ansari Zafar Ishaq
Published: November 2021

IIt was an intensely cold afternoon in Chicago on 26 February, 1975, whensome 20,000 members of the Nation of Islam, from across the U.S.A., filledChicago’s Amphitheatre to capacity. It was their Saviour’s Day, for them themost significant, and one might even say, the holiest day of the year. On thisday every year they gathered to celebrate the birthday of Fard Muhammad,whom they considered to be “God-in-Person,” the one for whom “praise isdue forever.” Although Saviour’s Day was observed across the U.S.A., itscelebration in Chicago had a special significance for members of the “Nationof Islam.” For in Chicago the guest of honour used to be none other than ElijahMuhammad himself, the “Messenger of Allah,n who addressed his followerswith marathon speeches that electrified them. Saviour’s Day was always aday of solemn rejoicing and celebration. This year, however, the membersof the Nation appeared tense and grim; their faces drawn, darkened withanguish. For only the day before, their leader, Elijah Mubarnmad, who hadled them for over forty years had breathed his last in Chicago’s Mercy Hospitalafter a prolonged struggle against numerous aliments.The news had left the members of the “Nation of Islam,” popularly knownas “Black Muslims," baffled, bewildered, speechless. They had immense loveand devotion for their leader, believing him to be the Messenger of Allah.They had witnessed many healthy changes in their own lives and in the livesof a very large number of fellow Blacks as a result of the teachings of ElijahMuhammad and of their association with his movement, the Nation of Islam.The wholesome influence of Elijah Muhammad was evident in their improvedeconomic conditions, the stability of their family life, their enhanced prestigein society, and even in their robust and elegant demeanour. Because of suchimprovements in their lives, some Blacks had begun to venerate Elijah Muipmmadalmost to the point of worshipping him. Moreover, there had developeda feeling among many followers of Elijah Muhammad that he was immortal.This feeling had perhaps received support in the past from the fact that onmany an occasion Elijah Muhammad had, almost miraculously, quicklyfecovered from very serious illnesses ...
Minerodutos e implicações socioambientais
Authors: Magalhães Júnior Antônio Pereira , Carvalho Regina Paula Benedetto de , Facury Daniel Machado , Camilo Gabriel Andrade , Ramanery Giovanna Soares
Published: November 2021

Minerodutos são considerados modais de transporte dentre os mais eficientes em termos de logística, mas a sua instalação e funcionamento podem trazer impactos, conflitos e desastres socioambientais como os riscos de escassez hídrica, por exemplo. No Brasil, a maior parte dos minerodutos está em Minas Gerais, estado com tradicional atividade minerária. Este artigo busca apresentar um panorama dos minerodutos em Minas Gerais e de suas implicações socioambientais, particularmente nos recursos hídricos. Foi realizada análise documental dos minerodutos instalados e projetados, a legislação, a repercussão na mídia e potenciais conflitos gerados por essas estruturas. São destacadas maiores incongruências durante as negociações de terras e licenciamento; durante a instalação dos minerodutos, sobre alterações na paisagem; e durante a operação, quanto ao uso da água; além de implicações políticas e econômicas de escala regional.
caderno e o lápis, armas indígenas contemporâneas
Authors: Honorato Suene
Published: November 2021

No romance Canumã: a travessia, de Ytanajé Coelho Cardoso (2019), uma família munduruku migra da aldeia para a cidade. A decisão é motivada pelas alterações no modo de vida tradicional, provocadas pelo estreitamento das relações com o mundo não-indígena. Nesse contexto, a educação formal é ressignificada como arma indígena, inscrita na continuidade das lutas contra o etnocídio. A partir dos movimentos entre aldeia e cidade, conhecimento tradicional e acadêmico, vida e literatura, discutirei as imagens dos processos formativos inscritas no romance e as possibilidades de se construir um diálogo entre culturas, saberes, mundos, em que as diferenças não sejam hierarquizadas.
Quase ausentes
Authors: Santos James Rios de Oliveira , Botoso Altamir
Published: November 2021

Detendo-se em terreno da literatura brasileira, mais especificamente ao âmbito das políticas públicas de distribuição de livros paradidáticos, o presente estudo, fazendo uso do método qualitativo e quantitativo, visa apresentar dados concernentes à baixa presença (ou quase ausência) de autores negros a compor o Programa Nacional Biblioteca da Escola (PNBE). Ademais, o trabalho centra-se no exame das obras Quarto de despejo, de Carolina Maria de Jesus, e O livreiro do Alemão, de Otávio Júnior, para ressaltar a importância de seus discursos antirracistas no âmbito de um programa de distribuição de livros, composto majoritariamente por autores não negros e por narrativas de temáticas afro-brasileiras diminutas. Este estudo conclui que políticas públicas de leitura, como o PNBE, deveriam acolher, quantitativamente, em seus acervos, um número maior de autores negros e obras mais representativas do ponto de vista racial e cultural, como as que aqui foram apontadas. Em síntese, o presente artigo tem o objetivo de propiciar e evidenciar, principalmente tendo em vista o público leitor dessas obras, o jovem negro, possibilidades de representação literária com as quais possam se identificar adequadamente.
Condição imigrante
Authors: Prates Lubi , Miguel Fernanda
Published: November 2021

Nesta entrevista, concedida em 2020 pela poeta Lubi Prates ao Grupo de Estudos em Literatura, Arte e Cultura (UFVJM/CNPq), a escritora fala sobre o momento presente da Pandemia da Covid-19 no Brasil, sobre a relação de seus versos com a questão do pertencimento e o permanente processo de reconhecimento, na ideia de tornar-se negra em diáspora, uma desconhecida ou uma eterna imigrante, e, sobretudo, sobre como planeja a liberdade através da poesia.
Clinical phenotype, diagnostics, strategy of hypophosphatasia therapy due to ALPL gene mutations in pediatric and adult patients
Authors: Leviashvili Zh. G. , Savenkova N. D.
Published: November 2021

Hypophosphatasia (HPP) ORPHA 436 is a rare disease with an autosomal recessive/autosomal dominant mode of inheritance due to mutations in the ALPL gene mapped on chromosome 1p36.12, encoding a nonspecific tissue isoenzyme alkaline phosphate (TNSALP). Currently, there are more than 400 known mutations in the ALPL gene. HPF is characterized by variability of manifestations from a mild course with minor damage to bones and teeth to severe forms with damage to the nervous system, lungs, and kidneys. In different countries, data on the prevalence of HPP differ, the average prevalence of severe forms is ~ 3.3 cases per 1 million newborns. In Europe, the prevalence of severe forms is 1: 300000 and moderately severe 1: 63701. The prevalence of mild HPP is thought to be much higher. The expected prevalence of severe forms in the Russian Federation is 1: 100000. GPP is diagnosed in patients of any age (with manifestation in utero, in childhood, or in adulthood).

HPP is an orphan disease, occurring in patients with damage to many organs and systems: bone (osteoporosis, rickets, fractures, growth retardation), lungs (hypoplasia of the lungs, respiratory failure), central nervous system (vitamin B-dependent convulsions), kidney (calciuria, nephrocalcinosis, chronic kidney disease). In the absence of timely enzyme replacement therapy for severe forms of HPP, characterized by a progressive course, the prognosis for life is unfavorable. The only effective treatment for patients is enzyme replacement therapy in combination with symptomatic therapy. The article presents the features of the phenotype and genotype, clinical forms of HPP (perinatal severe, lethal, perinatal benign, infant, pediatric, adult, and odontohypophosphatasia), methods of early diagnosis, the strategy of pathogenetic enzyme replacement therapy of severe and moderate forms in pediatric and adult patients. In the absence of a timely diagnosis, pathogenetic treatment of GFF, there is a high risk of progression with disability and death.
Predictor significance of β2-microglobulinuria in determining the risk of cardiovascular complications in patients with chronic ischemic heart disease
Authors: Levitskaya E. S. , Batiushin M. M. , Khripun A. V.
Published: November 2021

BACKGROUND. The relevance of identifying new biomarkers of the cardio-renal syndrome in patients with coronary heart disease is beyond doubt. It is promising to study the indicators of tubular dysfunctions as predictors of the risk of cardiovascular complications in patients without primary kidney pathology.

THE AIM. Analysis of the effect of β2-microglobulinuria on the prognosis of cardiovascular complications in patients with chronic ischemic heart disease in the long-term period after myocardial revascularization.

PATIENTS AND METHODS. The study included 90 patients with coronary artery disease and indications for myocardial revascularization. Coronary bypass surgery was performed in 64 people, coronary artery stenting - in 26. Clinical and anamnestic data were collected in all patients, standard laboratory and instrumental diagnostics were performed. In addition, the level of β2-microglobulin (β2-MG) in the first morning portion of urine was determined at different study dates. The endpoint was considered to be the presence of acute forms of coronary heart disease - myocardial infarction and unstable angina. Survival after 5.8 ±0.1 years after myocardial revascularization was 69 %.

RESULTS. A positive linear relationship of weak strength was established between the level of diastolic blood pressure (DBP) and β2-MG of urine obtained before myocardial revascularization (r = 0.28, p = 0.03). Moreover, the Kaplan-Meyer survival analysis showed the effect of an increase in β2-MG of urine over 0.2 ng/ml on the risk of AMI in the long-term period after myocardial revascularization (p = 0.025). It was found that an increase in the concentration of β2-MG in urine determined before myocardial revascularization is a statistically significant risk factor for the development of unstable angina in the long-term period after RM (χ2-criterion = 7.17, p = 0.007).

CONCLUSION. It has been shown that an increase in the concentration of β2-MG in urine, reflecting the presence of tubular dysfunctions, can be considered as a predictor of an unfavorable cardiovascular prognosis in patients in the long-term period after myocardial revascularization.