bluuebunny/crossref_metadata_2025 huggingface dataset:
Habilidades de liderazgo contra el matoneo en cadetes de primer nivel de la ESMIC
Authors: Cristancho-Acosta María Alejandra , Rodríguez-Arévalo Juan Napoleón
Published: June 2024

Este capítulo identifica el papel del liderazgo en la disminución de acciones relacionadas con el matoneo en el grupo de cadetes de primer nivel de la Escuela Militar de Cadetes “General José María Córdova”. Se aplica una metodología con enfoque cualitativo, mediante revisión documental acompañada de instrumentos y técnicas de investigación, como la entrevista, la encuesta cualitativa y la observación no participante, que permiten conocer la percepción de los cadetes acerca del liderazgo en un ambiente en que los comportamientos propios de la actividad militar pudieran ser confundidos con actitudes de matoneo. Se concluye que, en la formación de oficiales íntegros, es necesario fortalecer el liderazgo en cada fase y tomar decisiones acertadas para no afectar de manera negativa a los cadetes.
Formación de cadetes y alféreces generación Z en la ESMIC
Authors: Marín-Pinzón Lina María , Nossa-Ortiz Leonel
Published: June 2024

Este capítulo examina las características de los aspirantes que ingresan a la Escuela Militar de Cadetes “General José María Córdova” y que pertenecen a la gene-ración Z. Tales características deben tenerse en cuenta al aplicar la doctrina Damasco, implementada en el Ejército Nacional de Colombia desde 2016 y cuyos pilares se hallan consignados en los manuales fundamentales, especialmente, el MFE 7-0 y el MFE 6-22, referidos al líder. La ESMIC contribuye con el desarrollo de habilidades en dos ámbitos: el profesional y el militar y en la formación de cadetes y alféreces que, hoy centeniales, se desempeñarán como comandantes y líderes del Ejercito Nacional de Colombia.
Percepções Docentes em Relação ao Agir e Fazer Profissional no Contexto Pandêmico Vivido
Authors: Domingues Gleyds , Cunha Kátia , Lira dos Anjos José Ayron
Published: June 2024

A discussão teórico-metodológica construída no artigo tem como proposta analisar as percepções docentes que foram constituídas no contexto pandêmico, ocorrido entre os anos de 2020-2021, como resposta ao cenário educacional configurado, a qual demandou ajustes e acomodações ao agir profissional, marcado pelo caráter emergencial que produziu incertezas, mas ao mesmo tempo resiliência e superação. Diante deste cenário, foi eleita como questão problematizadora a seguinte pergunta: de que maneira o contexto pandêmico atingiu o fazer e agir profissional dos docentes, no que diz respeito à prática educativa concretizada no processo ensino e aprendizagem em sua estrutura e organização? Para que se compreenda este momento, fez-se uso da análise do discurso, a fim de identificar nos depoimentos dos docentes o dito, não dito e os silêncios. Busca-se com a investigação analisar não apenas os impactos da pandemia no âmbito da prática docente, mas o posicionamento assumido diante do seu contexto de trabalho. Ao final da análise, observa-se que os docentes se reinventam e buscam encontrar alternativas que sejam relacionais, coerentes e integradoras com o objetivo educativo almejado.
Práticas Orientadas e Reconstruídas
Authors: Zorzi Analisa , Aragón Rosane , Millan Gerson Luiz
Published: June 2024

Este artigo tem como objetivo compreender como ocorreu a formação do professor reflexivo a partir da problematização das práticas docentes que foram orientadas nos cursos XXX1 e YYY1 e, depois, reconstruídas nos espaços de atuação docente. A investigação foi desenvolvida a partir da seleção dos temas abordados nas publicações acadêmicas sobre os cursos. Para tanto, lançou-se mão do referencial que aborda a formação do professor reflexivo na leitura dos Projetos Pedagógicos de Curso (PPC) e dos dados obtidos em publicações sobre os cursos em revistas, anais, capítulos de livros e dissertações. Foi realizada a análise de conteúdo com o apoio do software Nvivo, para organizar os dados relativos à categoria “práticas orientadas e reconstruídas”, um dos temas abordados nas publicações. As publicações destacam que as alunas-professoras dos cursos incorporaram às suas atividades docentes na escola algumas ações empreendidas ao longo da formação, principalmente aquelas relacionadas à compreensão e à incorporação tanto das tecnologias digitais quanto da pesquisa como estratégia metodológica de organização do conhecimento.
U-Shaped Relationship Between Fibrinogen Level and 10-year Mortality in Patients With Acute Coronary Syndrome: Prospective Cohort Study (Preprint)
Authors: Li Yi ming , Jia Yuheng , Bai Lin , Yang Bosen , Chen Mao , Peng Yong
Published: June 2024

BACKGROUND

As an important inflammatory factor and a key participant in coagulation, fibrinogen has attracted attention in the management of acute coronary syndrome (ACS). However, the relationship between the fibrinogen level and the prognosis of patients with ACS remains controversial.In addition, the quantitative relationship between fibrinogen and the risk of mortality in a longer follow-up period needs further clarification.

OBJECTIVE

We aim to investigate the dose-effect of fibrinogen on ACS long-term prognoses with a prospective, large-scale, single-centre registry study.

METHODS

Patients were grouped by the five quantile levels of the plasma fibrinogen at admission. We used the Kaplan-Meier analysis to estimate the cumulative incidence of all-cause mortality. The predictive value of the fibrinogen level for the 10-year mortality was estimated by a Cox proportional hazards regression model. The impact of the fibrinogen on the 10-year mortality was assessed by a restricted cubic spline (RCS) curve, which was derived from an adjusted Cox proportional hazards regression model.

RESULTS

A total of 2405 consecutive ACS patients admitted to the West China Hospital between December 10th, 2010, and December 31st, 2012, were enrolled in this study. In the Kaplan-Meier analysis, the cumulative incidence of mortality was significantly different among the five groups (log-rank test: P<.001). Group 2 (fibrinogen level: 2.63-3.04 g/L) had the lowest incidence of mortality). In the Cox univariate regression analysis, fibrinogen was identified as an independent risk factor for the 10-year mortality (HR: 1.24 (1.15-1.35), P<.001).The RCS curve suggested strong U-shaped relationships between the adjusted risk of the 10-year mortality and the fibrinogen level, which was in accordance with the trend found in the Kaplan-Meier analysis. The risk of all-cause mortality decreased until the fibrinogen reached 2.81 g/L, and it then started to increase afterwards (P for nonlinearity <.001).

CONCLUSIONS

The long-term follow-up of nearly a decade and the quantitative RCS analysis suggested that the fibrinogen levels at admission have a significant impact on the long-term prognosis of ACS patients. The mechanisms underlying this phenomenon may be that fibrinogen acts as both an acute-phase protein and a subclinical inflammatory indicator. As an acute-phase protein, the fibrinogen level reflects the rupture of atherosclerotic plaques, while as a subclinical inflammatory indicator, it is involved in other metabolic processes, such as carbohydrate metabolism. Both of these mechanisms may contribute to its impact on the patients' long-term prognoses.The U-shape relationship between fibrinogen level and 10-year mortality suggested the need for long-term anti-inflammatory or metabolism treatment and the need to determine the fibrinogen level in patients with ACS.
Interpretable Machine Learning Models for Predicting In-Hospital Mortality in Patients with Chronic Critical Illness and Heart Failure: A Multicenter Study (Preprint)
Authors: He Min , Lin Yongqi , Ren Siyu , Li Pengzhan , Liu Guoqing , Hu Liangbo , Lei Lingyan , Wang Yue , Zeng Xiaocong
Published: June 2024

BACKGROUND

Heart failure (HF) is a leading cause of morbidity and mortality among patients in intensive care units (ICUs), particularly those with chronic critical illness (CCI).

OBJECTIVE

We aimed to develop and validate a machine learning (ML) model to predict in-hospital mortality for in CCI patients with CCI and HF.

METHODS

Retrospective data encompassing medical records from over 200 hospitals were obtained from the Medical Information Mart for Intensive Care III (MIMIC-III), MIMIC-IV, and eICU Collaborative Research Database (eICU-CRD). Patients diagnosed with CCI and HF at their first ICU admission were included. The MIMIC-III and -IV datasets were used as a derivation cohort, while that from eICU-CRD was employed as a validation cohort. Key predictive features were identified utilizing the recursive feature elimination with 10-fold cross-validation method. Subsequently, multiple ML algorithms were evaluated, including Random Forest, K-Nearest Neighbors, Support Vector Machine (SVM), Extreme Gradient Boosting, Naive Bayes, Light Gradient Boosting Machine, and Adaptive Boosting. The performance of the models was assessed via metrics such as area under the receiver operating characteristic curve (AUROC), decision curve analysis, accuracy, sensitivity, specificity, and F1 score. Furthermore, model interpretability was enhanced by applying the SHapley Additive exPlanations (SHAP) and Local Interpretable Model-Agnostic Explanations (LIME) methods, providing insights into the contribution of individual features to the predictive outcomes.

RESULTS

A total of 780 (males: 451 [57.8%]) and 610 (males: 343 [56.2%]) patients with CCI and HF were allocated to the derivation and validation cohorts, respectively. Eleven features were selected to develop the prediction models. Among all models, the SVM algorithm-based model demonstrated high predictive accuracy (derivation cohort: AUROC, 0.781; sensitivity, 0.739; specificity, 0.691; and F1 score, 0.613; validation cohort: AUROC, 0.683; accuracy, 0.645; sensitivity, 0.607; specificity, 0.656; and F1 score, 0.44). The SHAP and LIME analyses evaluated the feature contributions, highlighting Sequential Organ Failure Assessment score, oxyhemoglobin saturation, diastolic blood pressure, and systolic blood pressure as significant predictors of in-hospital mortality.

CONCLUSIONS

The SVM model developed in this study effectively predicts in-hospital mortality in patients with CCI and HF and can serve as a reliable tool for early intervention and improved patient management. Furthermore, this ML model combines high accuracy with interpretability, thereby substantially contributing to clinical predictive analytics.
Ecological Sensitivity Assessment of Xinyi City in Guangdong Province Based on GIS and AHP
Authors: Ye Xiaodong , Wang Ruei-Yuan
Published: June 2024

Ecological sensitivity analysis is an important basis for urban planning and layout. This article selects six ecological evaluation factors, including altitude, slope, aspect, water environment, vegetation NDVI, and land use, to construct an ecological sensitivity evaluation system for Xinyi City. Using the spatial analysis techniques of GIS and the Analytic Hierarchy Process (AHP), a comprehensive evaluation was conducted on six ecological evaluation factors. Meanwhile, the natural breakpoint method was used to divide the results into five levels: extremely sensitive area, high sensitive area, medium sensitive area, low sensitive area, and non-sensitive area. The results indicate that the ecological sensitivity of Xinyi City is generally high, and land use type, vegetation coverage, and water environment are the main factors affecting ecological sensitivity. The five sensitive areas, from non-sensitive to extremely sensitive, account for 0.71%, 18.44%, 38.88%, 33.01%, and 8.96% of the total area of the city, respectively. The highly sensitive areas of Xinyi City are distributed in the northeast, while the non-sensitive areas are distributed in the southwest. The comprehensive evaluation of ecological sensitivity and spatial layout in this article can provide a basis for land use construction planning and ecological environment protection in Xinyi City.
Entre la biopolítica, la invención de la maternidad y el género. El aborto en Chiapas
Authors: Gómez García Irazú
Published: June 2024

En el presente artículo identifico algunas de las limitantes que enfrentan las mujeres al decidir interrumpir un embarazo en Chiapas. Tomo como punto de partida el análisis de tres procedimientos jurídicos llevados a cabo entre las décadas de 1970 y 1990, por el delito de aborto en agravio de la sociedad, en la ciudad de San Cristóbal de Las Casas. Desde el modelo del análisis histórico de larga duración (Braudel 1970), analizo la manera en que el despliegue biopolítico de género estableció lógicas de dominación en los expedientes revisados. Las desigualdades señaladas para las acusadas se colocaron en los campos de la justicia, la salud, y en el ámbito de sus relaciones personales. Por último, considero algunos de los factores del contexto actual que, más allá de la permanencia de una biopolítica de género, continúan afectando la posibilidad de la despenalización, así como la autonomía reproductiva de las mujeres a nivel local.
Civilización y sociedades indígenas en el Caribe: conexiones pedagógicas entre las revistas La Escuela Primaria de Yucatán y Revista de Instrucción de Colombia al finalizar el siglo XIX
Authors: González Rey Diana Crucelly
Published: June 2024

En este texto se compara y se exponen las conexiones presentes entre los discursos de dos revistas pedagógicas al finalizar el siglo xix: la revista La Escuela Primaria de Yucatán, en México, y la Revista de Instrucción Pública de Colombia. Se analiza el ideal de civilización, un concepto polisémico presente en las fuentes documentales de ambos contextos, que se asoció íntimamente con la actividad educativa. Asimismo, se evalúa la construcción de imaginarios y representaciones en torno a las sociedades indígenas que habitan el Caribe: mayas, arahuaw y wayuú durante la consolidación de los jóvenes Estados latinoamericanos.
La migración de productores de caña en el auge del ingenio azucarero en puerto rico durante el siglo XIX: el caso de juncos
Authors: Alemán Iglesias Javier
Published: June 2024

En este trabajo presentamos una breve descripción de la relación entre la inmigración de extranjeros y el auge del ingenio de caña azúcar durante el contexto del siglo xix. La Real Cédula de Gracias de 1815 facilitó la inmigración de extranjeros y muchos de ellos establecieron ingenios azucareros en diversos lugares del país. En el artículo también se describirá el caso de los ingenios de la región centro oriental, haciendo mayor énfasis en el municipio de Juncos.
Design of Low Power Double Tail Dynamic Comparator
Authors: G Poornima
Published: June 2024

Abstract: Dynamic regenerative comparators are being used more and more to enhance power and speed economy in analog-todigital converters. These converters must be extremely low-power, area-efficient, and high-speed. In this case, the DCs (DC) power is analyzed. A new DC is suggested, modifying the traditional double-tail comparator circuit for quick and low-power functioning even at low supply voltages, in accordance with the analysis that has been provided. Little transistors are added, and the construct is kept simple. Additionally, a new DC in line with on the suggested double-tail topology is provided; this comparator doesn't need a boosted voltage or excessive transistor stacking. Additionally, a latest DC is narrated that it doesn’t not require boosted voltage or the stacking of an excessive number of transistors, based on the double-tail structurethat has been proposed. Time for Latch delay is greatly decreased by just incorporating a small number of minimum-size transistors into the traditional double-tail DC. Comparing this improvement to the traditional DC and double-tail comparator, significant power reductions are also achieved. The construction of a distinct input and cross-coupled stage is the foundation of the double-tail DC. Fast functioning across a broad common-mode and supply voltage scale is made possible by this separation. This work presents a thorough investigation of DC delays for a variety of topologies. The probe results are validated by the results of simulation in 90 nanometer CMOS technology. It is demonstrated that the DC hasa much lower power consumption. At voltage, the comparator's maximal clock frequency is raised to 2.5 Hz, consuming 6.76 μW in the process.
BURYAT TRADITIONAL BUDDHISM IN THE CONTEXT OF GLOBALIZATION AT THE BEGINNING OF THE 21ST CENTURY
Authors: Varnavskiy Pavel
Published: June 2024

At the beginning of the 21st century, the traditional Buryat sangha faces a new challenge, which is connected to processes of increasing globalization that concern all the greater territories of Russia. This paper examines Buryat Buddhism in the light of a variety of global tendencies that are characteristic of contemporary religious processes. How does Buddhism in the form of the traditional Buryat sangha react to its entry into the ‘condition of globality’? The author argues that, as a reaction to globalization, Buddhism supports the formation of a ‘glocal’ religiocultural meta-narrative that is easy to understand, transparent for the whole populace of the Buryat Republic, and thus provides a structure for its poly-ethnic community. Simultaneously, the logic of the development of Buryat Buddhism allows the conclusion that its embedment in global trends of religiousness is more likely to be a consequence of necessity, characterized by protective adaptation, than of a progressive developmental strategy of the Buddhist Sangha.
БОЛЬШЕВИКУУД МОНГОЛЫН УЛАМЖЛАЛТ ШАШНЫГ УСТГАХААР ХЭРЭГЖҮҮЛСЭН БОДЛОГО (1921-1939)
Authors: З Лонжид
Published: June 2024

Зөвлөлт засгийн удирдлага буюу большевикууд Монголд эрхшээлээ тогтоох зорилгоор 1921-1939 онд монголчуудын уламжлалт шашныг устгахдаа харилцан хамааралтай гурван цогч арга хэрэглэсэн тухай хураангуй өгүүлэв.
BUDDHIST MONASTERIES AND STATE SUPPORT IN MONGOLIA A BRIEF OVERVIEW
Authors: Krisztina Teleki
Published: June 2024

During the history of Mongolian Buddhism the State has always significant role in supporting religion and monasteries. Möngke Khan held the first religious dispute of Buddhist, Muslim and Christian monks in the 13th century and gently allowed all foreign devotees to practice their own religion and pray for the Mongolian State. This Mongolian court`s relationship deepened with Buddhism during the period of Khubilai Khan (13th century), Altan Khan and Ligdan Khan (16th century, 17th century), Avtai Sain Khan (16th century), and also with the Khalkha Khans during the Manchu period. The Eighth Bogd Jebtsundamba Khutugtu became the Bogd Khaan, the theocratic king of the sovereign Mongolia (1911-1921): his realm brought the Golden Age of Mongolian Buddhism and monasteries. The only political formation that ceased Buddhism and the operation of monasteries was socialism, when only one monastery, Gandantegchenlin Monastery could run operation from 1944 until the democratic changes in 1990 when religious practices became free again. The presentation will cite some examples from the supportive relation and fruitful cooperation of emperors, khans, nobles, statesmen with Buddhist monasteries, monk communities and monks, and also mention some present-day problems including similarities and differences. For instance, during the Manchu period monks were released from ‘state oblige’ including military services and taxation. In the 1930s when socialism started monks were enrolled to the army. Those monks, who did not want to perform military service had to pay military tax. Monks were registered based on their ranks, age, and incomes in the 1920s-1920 as the State and Religion become totally separated, and finally religion was ceased, and monasteries were destroyed. Religious practices became are free again in the 1990s, many monasteries were rebuilt, new monasteries were founded, and the number of monks is increased. However, as monasteries are handled equal to other organizations and enterprises they pay tax. Monks themselves have military obligation and pay different types of taxes. The presentation will raise some ideas about the old, current and future relations of the State and Monast
ABORDAGEM CTSA EM LIVROS DIDÁTICOS: UMA ANÁLISE EM OBRAS DA ÁREA DE CIÊNCIAS DA NATUREZA DO NOVO ENSINO MÉDIO
Authors: Rezende Elisangela , Suart Rita de Cassia
Published: June 2024

Esta pesquisa se propõem a realizar uma análise de livros didáticos da área de Ciências da Natureza e suas Tecnologias, recomendados pelo Ministério da Educação por meio do Programa Nacional do Livro Didático (PNLD-2021), direcionados ao Ensino Médio, com o objetivo de investigar como a abordagem de contextualização Ciência, Tecnologia, Sociedade e Ambiente é desenvolvida ao longo do seu conteúdo, quando relacionado ao componente curricular Química. Para isso, os procedimentos metodológicos tiveram como base a pesquisa qualitativa e a análise dos dados caracterizou-se pela Análise de Conteúdo. A pesquisa se deu por meio da análise de 3 unidades/capítulos de 3 livros didáticos, com base nos referenciais de Marcondes et al. (2009) e Silva e Marcondes (2010). A partir das análises realizadas, identificou-se que os livros ainda apresentam uma abordagem pouco problematizadora e a maioria de seus conteúdos não apresenta uma preocupação com fatores que contemplem o campo científico e tecnológico, bem como suas implicações sociais e ambientais, de forma a articular o ensino de Química com a abordagem CTSA. Além disso, poucos exercícios exigem alta demanda cognitiva dos estudantes e os experimentos são, em sua maioria, baseados em uma perspectiva de verificação de fatos. Neste sentido, embora as obras indiquem que os seus conteúdos estão apoiados na perspectiva da contextualização e problematização CTSA, muito ainda precisa avançar para que esta abordagem seja contemplada conforme o entendimento da literatura da área. Isso mostra que ainda precisamos avançar quanto a proposição de materiais instrucionais que auxiliem o professor no desenvolvimento de uma prática para a promoção de habilidades, visando uma formação mais crítica e transformadora da realidade por nossos estudantes.
Diagnóstico comparativo entre ressonância magnética e tomografia computadorizada na detecção da neurocisticercose
Authors: Da Conceição Neto André Ponciano , Ferreira Taiara Silva , Santos Gilmar de Jesus , Matos Silva Carlos Danilo Cardoso
Published: June 2024

A neurocisticercose (NCC) tem sua caracterização pelas lesões no sistema nervoso central (SNC) ocasionado pelo cisto do parasito Taenia solium. Acontece a reação inflamatória no organismo resultando na degeneração do cisto larval causando sintomas clínicos como episódio epiléticos. O objetivo deste estudo foi comparar as características de imagem na tomografia computadorizada (TC) e na ressonância magnética (RM), destacando a eficácia de cada técnica no diagnóstico da neurocisticercose. Estudo de revisão da literatura sistemática, tendo o Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) como método e utilizando mecanismos de busca na base de dados da Scientific Electronic Library Online (Scielo), Medical Literature Analysis and Retrieval System Online (MEDLINE) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). Foram utilizados artigos datados de 1998 a 2018 na língua portuguesa e inglesa. Os resultados indicam que a TC e a RM produzem imagens satisfatórias e objetivas quando analisados em pacientes que possuem sintomatologia positiva para a NCC. A tomografia permite uma visualização melhor dos cistos calcificados, enquanto a ressonância magnética possibilita uma melhor definição tecidual.
Cultivating Digital Wisdom in the Deep Future
Authors:   Beijing Institute of Technology, Zhuhai, Anthony Marcus T.
Published: June 2024

The central focus of this paper is on the concept of Digital Wisdom, which is defined as the degree to which a person is in conscious relationship with digital environments and technologies. The author identifies and discusses the three domains of Digital Wisdom: “know thyself,” “know the humans,” and “know the machines.” Through a comprehensive analysis of literature, tools, and processes, the author provides insights into how netizens – individuals in online environments – can develop Digital Wisdom within each of these domains. The article also explores the interplay between the three domains and highlights the potential consequences of AI advancements on human cognition and mental well-being. By offering a detailed framework for cultivating Digital Wisdom, this paper contributes to the ongoing discourse on fostering a more balanced and holistic approach to understanding and engaging with the digital world amidst the rapidly advancing AI landscape, and in doing so create a Deep Future.
Analysis of random mutagenesis in the improvement of a commercial opaque beer brewing yeast strain
Authors: Mangwanda Tinashe W. , Moyo Nyaradzai , Ncube Thembekile
Published: June 2024

Mutagenesis can generate genetic diversity and novel phenotypes in yeast
strains. This study evaluated physical and chemical mutagenesis for
improvement of an industrial Saccharomyces cerevisiae opaque beer
strain. The yeast strain was exposed to mutagens, long enough to cause
50-95 % lethality with subsequent assessment of surviving cells for
favourable characteristics. Yeast batches were mutagenized using ethyl
methanesulfonate (EMS), and by exposure to ultraviolet light and visible
light. EMS caused a dose-dependent decrease in survival from 100 %
viable cells without EMS addition, to 10 % at 100 μg/mL, and 0 % at
200-300 μg/mL. There was approximately 10 % survival under ultraviolet
light exposure observed at 25 minutes. Ultraviolet light resulted in
approximately 10 % survival at 25 minutes of exposure. Visible light
showed negligible mutagenic effects, with white light had the least
impact on survival. EMS mutagenized cells achieved 4% alcohol content
in 48 hours, versus 72 hours for controls, indicating accelerated
fermentation. EMS mutants utilized 37 % more sugar on average than
controls but produced lower total acidity in the final product. Thus,
EMS mutagenesis produced favourable phenotypes including faster
fermentation, higher alcohol yield, increased sugar consumption, and low
off-flavours. With appropriate screening, EMS mutagenesis could generate
improved opaque beer strains with desirable industrial characteristics.
This study demonstrates the potential of random mutagenesis to
sustainably enhance yeast strains for modern beer production.
A systematic review of exercise as a therapeutic intervention to improve Quality of Life and Cancer Related Fatigue in Paediatric Cancer Care
Authors: Sheldon-Wilson Holly , Manias Ren , C Juliet Gray
Published: June 2024

Objective: To review the evidence that personalised physical activity is
a feasible and acceptable means of significantly improving quality of
life (QoL) and cancer related fatigue (CRF) in childhood cancer.
Methods: Seven databases/registers were searched for studies evaluating
exercise interventions in paediatric cancer (2013-2023). Studies
included patients ages 3-25 years, with any cancer type, undergoing
exercise interventions during active treatment. Thirteen studies (551
participants) were included. Primary outcome measures analysed were CRF
and QoL. Results: Three of eight studies (N=105) measuring CRF revealed
significant reduction in total fatigue score (p=0.001, 0.01, 0.026). All
others demonstrated a non-significant reduction in CRF in the
intervention group (mean -5.7 (±8.82 pooled SD)). One of ten papers
(N=99) measuring QoL reported significant improvement (p=0.014), with
non-significant favourable outcomes (mean change +3.47) in all remaining
studies. No adverse events were reported. Conclusion: Physical activity
is a feasible way to improve CRF and QoL in children undergoing cancer
treatment.
Agreement between two traditional lunging protocols for physical fitness training in untrained horses
Authors: Huangsaksri Onjira , Sanigavatee Kanokpan , Poochipakorn Chanoknun , Sukhong Patskit , Wonghanchao Thita , Chanda Metha
Published: June 2024

Background: Lunging is a training method that is performed in a
round pen or on a lunge line. However, there is no consensus on applying
lunging techniques for physical fitness training. Objectives:
To investigate the effort intensity, autonomic responses, and method
agreement in applying different lunging protocols to untrained horses.
Study design: A non-randomised control trial. Methods:
Sixteen untrained horses (aged 13.6 ± 6.3 years and weighing 358 ± 47.4
kg) were studied. Each horse was lunged with a similar programme on a
lunge line and, subsequently, in a round pen at a two-day interval. The
heart rate variability (HRV) and effort intensity, indicated as a
percentage of maximum heart rate (%HRmax), were determined pre-lunging,
during lunging at distinct gaits, and at 30-minute intervals for 120
minutes post-lunging. The correlation and method agreement between the
two lunging methods were analysed with Pearson’s correlation coefficient
and Bland–Altman plots, respectively. Results: The horses ran
faster and covered longer distances during exercise on a lunge line than
in a round pen. The effort intensity during cantering reached moderate
levels (75.1 ± 2.4% HRmax) with occasional high-intensity levels (88.1
± 1.3% HRmax) via both lunging methods. The HRV reached a minimum
during cantering and returned to the baseline 120 minutes post-lunging.
The HRV parameters (SDNN, RMSSD, LF, HF, SD1, and SD2) were strongly
correlated ( r ≥ 0.97 and p <
0.001 for all) with a large correlation effect size (R
> 0.85) and excellent agreement
(average differences were within mean ± 1.96 SD) between the two lunging
methods. Main limitations: The running speed and distance
reported during lunging may not be entirely accurate due to the manual
calculation required. Conclusions: Lunging can provoke optimal
physiological responses in horses. The two tested lunging methods may be
applied interchangeably for physical fitness training.
Navigating the Future: The Promises and Pitfalls of Artificial Intelligence in Otolaryngology in the United Kingdom
Authors: Alfuhaid Rayan
Published: June 2024

Artificial Intelligence (AI) has garnered worldwide attention across
public, academic, and technological sectors for its potential to
revolutionize healthcare by improving cost and quality of care. This
review critically examines the promises of AI-driven innovation in
Otolaryngology (Ear, Nose, and Throat), a surgical specialty
encompassing various subspecialties offering inpatient and outpatient
services. The analysis focuses on AI’s application in diagnostic
support, precision medicine, image analysis, automation, and patient
education, while also addressing the ethical and practical
considerations. Despite the current high risks associated with AI use in
clinical settings, there is significant potential for overcoming these
challenges. The National Health Service (NHS) in the UK is adopting AI
as part of its ‘Long Term Plan’ to enhance clinical practice and patient
management. However, the adoption of AI in Otolaryngology requires a
cautious approach to balance the risks of bias, reliability issues, and
the ‘black box’ phenomenon. Proper education and training in AI for
healthcare professionals are essential to ensure a knowledgeable
workforce capable of utilizing these emerging technologies effectively.
Public Attitudes Toward the Tampon Tax.
Authors: SHAHID SABA , Shahid Shiza , Sacco Donald , Stepanova Elena V.
Published: June 2024

Menstrual products have historically been subject to an extra cost known
as the “tampon tax,” which is still imposed in 21 US states, including
Georgia and Mississippi, with a range of 4-7%. We aimed to explore the
attitudes of people toward the tampon tax. We assessed these attitudes
using a survey completed by 251 participants. The results revealed women
were more familiar with the tampon tax as compared to men, but overall
familiarity was low. Women were also more in favor of eliminating this
tax and strongly believed that this tax affects gender equity relative
to men. For both men and women, greater familiarity with this tax was
associated with stronger beliefs that it negatively impacts gender
equity and more support for its elimination. We also found a significant
role of political orientation, where Democrats and Independents relative
to Republicans were more in favor of eliminating this tax and believed
more strongly that this tax impacts gender equity. This research
suggests that support for the tampon tax is relatively low, it varies by
gender and political orientation, and a general lack of familiarity with
the tampon tax may contribute to why there has not been more advocacy
for its removal.
Output formation containment of heterogeneous singular multiagent systems using adaptive protocols
Authors: Liu Xiaofan , Sheng Kai , Yan Yunyi
Published: June 2024

In this paper, the output formation containment control problem for
heterogenous singular multiagent systems is studied. The purpose of this
control is to drive the output of leader agents reach an time-varying
formation and take containment action for the follower agents. Firstly,
two novel distributed adaptive protocols are designed, which rely on the
relative outputs information of agents without measuring and
transmitting the states of agents. Then, the formation containment
control problem can be simplified into the admissible analysis of
coupled nonlinear singular systems by constructing the model
transformation. The output formation control conditions related on
spectrum radius of weighted adjacency matrix are obtained based on the
bounded real lemma and admissible analysis. In addition, the adaptive
protocols based on the state of virtual leader are proposed, which can
drive the agents achieve formation containment control more quickly when
the state of virtual leader is known. Finally, the simulation results
verify the feasibility of output formation containment control.
Review: Advancing Battery Recycling Li-ion Current Trends and Future Outlooks (EVs And Hybrid Vehicle’s)
Authors: Mohammed Fazurulla
Published: June 2024

As we move towards the future, the shift to electric transportation is
crucial in reducing our carbon footprint and enhancing air quality.
Electric vehicles (EVs) are essential to meet consumer needs and achieve
this goal. However, this growth presents challenges such as increased
demand for materials like lithium and cobalt leading to scarcity and
environmental concerns. Moreover, proper management of EV batteries is
crucial to recover valuable components and minimize environmental impact
as they are hazardous. As EVs approach the end of their life, proper
disposal or recycling is necessary to prevent environmental
contamination and maximize resource recovery. I evaluate current
approaches to recycling and reusing electric-vehicle batteries and
suggest areas for future progress.
Super-utilization interventions - failing or evolving in complex systems? Part 1. A snapshot and scoping review of the literature
Authors: Martin Carmel
Published: June 2024

Introduction: Super-utilization (frequent acute hospital care use or
frequent emergency department (ED) utilization and readmissions)
describes high rates of emergency department visits and hospital
admissions by some individuals. A large empirical literature which has
not shown significant improvements over the past 12 years. Reducing
healthcare costs per capita have focussed on Super-utilization, system
transformation, and care management. The complex dynamics systems
driving Super-utilization lack prominence. Aims: The review aims to
uncover essential frameworks and articles to interrogate the mindset of
Super-utilization and its evolution to illuminate current understandings
and prevailing themes. Methods: Utilizing primary articles, search terms
were refined iteratively for searches on Super-utilization,
Super-utilizer, and Care Management themes. Articles were intentionally
chosen to illustrate primary themes. The review included the most recent
and relevant articles to provide a narrative of the diverse set of
taxonomies related to Super-utilization Findings: Common to all 4
searches were utilization outcome measures. Care Management was the
second common theme. Needs were the lowest frequency in
Super-utilization 8% compared with Superutilizers 20% and Care
Management 24-25% searches. Systematic reviews and key studies
demonstrated limited success of care management, including system
transformation from health into social care. Centralised policies such
as the Triple Aim have inherent polarities. Health services must contain
costs and meet felt needs that emerge from under resourced personal
journeys and underserved communities. Conclusion: Super-utilization is
an expanding concern within academic literature. Efforts to reduce
frequent and multi-dimensional acute care presentations using current
care models appear ineffective. The predominant focus on utilization and
costs, wedded to a care management model, has diverted attention from
taking both a more needs-centred and a broader complex systems
perspective on Super-utilization. Distributive justice asks whether
social funding should be increased in preference to expanding current
health spending.
Enhanced DNA Extraction from Fungal Cells: Exploring the Advantages of Blastospores Versus Mycelia
Authors: Sabbagh Dalal , Akl Hadi , Khoury Karen El , Khatib Ahmad El , Dimassi Hani , Dimassi Sarah , Tokajian Sima , Nemer Nabil , Khoury Charbel Al
Published: June 2024

Beauveria bassiana, a necrotrophic fungus thriving in diverse
ecosystems, predominantly on arthropods, holds significant importance as
a biological agent. The escalating relevance of genetic studies on fungi
necessitates the development of efficient and robust DNA extraction
techniques to ensure the acquisition of high-quality DNA. B.
bassiana was cultured to produce either mycelia or blastospores. Six
DNA extraction procedures and two pre-treatment conditions were
independently adopted to evaluate their efficacy in obtaining high
molecular weight, high concentration, and high-quality DNA from both
blastospores and mycelia. Quantification of the extracted DNA was
achieved through qPCR analysis targeting the single-copy γ-Actin gene,
with validation of amplification specificity and determination of
amplification efficiency conducted through standardized protocols and
standard curve construction. Statistical analysis indicated that, under
all conditions, blastospores yielded more promising results.
Blastospores exhibited a mean antilog of 5.0344 + 0.20 for DNA copy
concentration, surpassing mycelial cells averaging 2.5069 + 0.20.
Additionally, blastospores outperformed mycelial cells in DNA quality,
as evidenced by their 260/280 and 260/230 ratios (31.5% within the
range for blastospores vs. 7.4% for mycelial cells, p-value=0.002).
Moreover, blastospores produced higher molecular weight DNA, averaging
10770.5 base pairs compared to mycelial cells at 8139.0 base pairs
(p-value <0.001). This study underscores the superiority of
DNA extraction from blastospores compared to mycelial cells of B.
bassiana. These findings have broader implications for other dimorphic
fungi and open new avenues in the realms of molecular biology and
microbial ecology, particularly in genetic and evolutionary studies.
Funcionalidad familiar y depresión en estudiantes universitarios en el Departamento del César
Authors: Tirado Vides María Margarita , Redondo Marín Miladys Paola , Hernández Mieles Gloria , Jiménez Ruiz Luz Karine , Guerra Muñoz Martha Esther
Published: June 2024

La familia es la base de la sociedad y tiene entre sus múltiples funciones ser red de apoyo para cada uno de sus miembros en diferentes contextos incluyendo entre otros eventos su formación académica y/o profesional. Las disfunciones en el seno familiar afectan de manera directa el estar de sus integrantes en el entorno social. El objetivo de esta investigación fue establecer la relación entre funcionalidad familiar y depresión en estudiantes universitarios del departamento del César. Para esto se llevó a cabo una metodología cuantitativa transversal de alcance correlacional. La población estuvo conformada por 854 estudiantes que cursaron primer semestre en el año 2021-1 en diferentes programas ofrecidos por la universidad Popular del César. Para la recolección de la data se utilizó el Apgar familiar y el Inventario de Depresión de Beck. Los hallazgos descriptivos evidenciaron la presencia de signos de depresión y disfuncionalidad familiar en un alto porcentaje de estudiantes, se evidencia también la presencia de casos clínicos de depresión en mujeres más que en hombres. Se concluye que no existe relación entre la funcionalidad familiar y depresión en los estudiantes de primer semestre, por lo tanto, la evidencia empírica no permite rechazar la hipótesis nula.
Universidade Corporativa
Authors: Leiva de Luca Plinio Paulo , Sales Giza Guimarães Pereira
Published: June 2024

Neste artigo apresenta-se uma proposta para criação de um modelo de Universidade Corporativa (UC) dedicada ao fortalecimento da organização empresarial, com ênfase no desenvolvimento educacional e nas habilidades socioculturais dos seus funcionários e colaboradores. No entanto, é facilmente perceptível que o objetivo dessas instituições deveriam ir além da melhoria da produtividade e da incorporação de estratégias de desempenho. Nesse sentido, apresentamos uma proposta para a criação de uma UC que se dedique ao fortalecimento da organização empresarial, destacando o desenvolvimento educacional e sociocultural dos funcionários e colaboradores. O trabalho desenvolvido resultou da articulação com a pesquisa exploratória e bibliográfica que serviu de base para o referencial teórico-metodológico das discussões aqui apresentadas, além de uma vivência teórico-prática vivenciada pelos pesquisadores, com uma proposta de uma UC que crie as condições de desenvolvimento sociocultural de seus membros.
Title and dedication as components of an autobiographical paratext in dialogical communication with the addressee
Authors: Лаврова С.Ю.
Published: June 2024

В данной работе рассматривается анализ заглавия и посвящения в автобиографическом паратексте эссе «Набережная неисцелимых» поэта И. А. Бродского. Цель работы обусловлена исследовательским интересом к актуальному для современной филологии феномену паратекста как пограничному элементу литературного текста, задающему рамки интерпретации. Обосновывается возможность терминологического расширения известной классификации паратекста, предложенной Ж. Женеттом в 1982 г., за счет введения термина «автобиографический паратекст». Доказывается, что автобиографический паратекст И. А. Бродского репрезентируется в эссе как в эксплицитной, так и имплицитной форме. Экспликация паратекста выражается в конкретизации реального имени (художника Роберта Моргана) и в описании реально существующей набережной в Венеции (Fondamenta degli incurabili). Импликация содержит информативную затекстовую часть – посвящение другу, развернутую информацию о котором читатель получает из автобиографических источников.

The article analyses the title and dedication in the autobiographical paratext of the essay ‘Watermark’ by I. Brodsky. The study is driven by the research interest in the phenomenon of paratext relevant for modern philology as the border element of the literary text that sets the framework of the interpretation. The author of the article introduces the term ‘autobiographical paratext’ which broadens the classification of paratext proposed by Gerard Genette in 1982. It is proved that I. A. Brodsky’s autobiographical paratext is represented in the essay in both explicit and implicit forms. The explication of paratext is expressed in the use of a real name (artist Robert Morgan) and in the description of a real embankment in Venice (Fondamenta Degli Incurabili). The implication contains an informative out-of-text part – a dedication to a friend, extensive information about whom the reader obtains from autobiographical sources.
Professionalitet project as a secondary level vocational education
Authors: Листвин А.А. , Гарт М.А.
Published: June 2024

Взятый в России курс на экономику предложения предусматривает ее развитие на основе наращивания производительных сил. Реализация такой стратегии предполагает обновление системы воспроизводства квалифицированных кадров, что затрагивает систему среднего профессионального образования, осваивающую в настоящее время проект «Профессионалитет». Авторы статьи, учитывая количественные изменения в системе среднего профессионального образования в рамках данного проекта, предлагают рассматривать «Профессионалитет» в качестве начальной ступени в системе непрерывного профессионального образования.

Russia's course towards the supply-side economy provides for its development on the basis of increasing productive forces. The implementation of such a strategy implies the renewal of the qualified personnel system, which affects the system of secondary vocational education and the ‘Professionalitet’ project. The authors of the article, taking into account the quantitative changes in the system of secondary vocational education within the framework of this project, propose to consider ‘Professionalitet’ as an initial stage in the system of continuous vocational education.
Resveratrol’s Action against Viral Infections
Authors: WM* Dos Santos
Published: June 2024

The biological activity of resveratrol (3,5,4’-trihydroxy-trans-stilbene) has been the subject of extensive study in the treatment of various diseases due to its anti-inflammatory, antioxidant and anticancer activities, as well as its minimal toxicity and side effects. It has been widely accepted that resveratrol also has antiviral activities. In this mini-review, we summarize resveratrol’s antiviral mechanisms. Since viral infections are often accompanied by inflammation, the TLRs/NF-κB signaling pathways are key and common molecular mechanisms for resveratrol to exert anti-inflammatory and antiviral effects.
Fabrication of a CAD-CAM Custom Modified Anatomic Healing Abutment based on Gingival Profile Measurement in an Instructional Dentition Model - A Dental Technique
Authors: D* Boldbaatar
Published: June 2024

This report introduces a new modified anatomic healing abutment designed to shape the gingival contour peri-implants. Experimental implants were placed in a dentition model after extracting a maxillary central incisor and a mandibular first molar. Scanning procedures were performed on the model. The reduction in gingival contour dimensions at the neck of the implants guided the development of the modified abutment. CAD/CAM technology was used to manufacture a titanium-based abutment, reducing chairside workflow time and minimizing costs. The present report presents the evolutionary progression of a modified anatomic healing abutment through its incorporation within a dentition model, thereby showcasing an avantgarde technology paradigm and methodological. The modified healing abutment has been intricately fashioned to cater to delayed implantation circumstances, in stark contrast to its conventional counterpart employed in immediate implantation scenarios. Its primary objective resides in the meticulous cultivation of an exquisitely defined gingival contour, thereby augmenting the aesthetic visage of the anterior dental region.