bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of the Relationship Between Clinical Practice Stress and Professional Self-Esteem in Nursing Students
Authors: ÖZ Fatma Betül , BİLGİLİ Naile
Published: August 2023

This study aims to investigate the relationship between clinical practice stress and professional self-esteem in nursing students in terms of some variables. The study is of a descriptive-relationship-seeking type. The study population consisted of 806 2nd, 3rd, and 4th-year students studying at Gazi University, Faculty of Health Sciences, Department of Nursing in the fall semester of 2022-2023. It aimed to reach 261 students by calculating the sample of which the population of the study is known. The sample of the study was obtained by systematic sampling method. The data collection forms used were the Personal Information Questionnaire, the Clinical Stress Questionnaire, and the Professional Self-Esteem Scale. According to the research results, there is a statistically significant difference between the medians of the professional self-esteem scores related to department choice, satisfaction with the department, positive communication with instructors, and positive communication with medical staff (p< 0.001). As a result of our study, it was found that the older students, those who had voluntarily chosen the department, those who were satisfied with the department, those who had no difficulty meeting expectations, and those who were considering continuing in the profession had higher professional self-esteem. There was no relationship between clinical practice stress and professional self-esteem.
Repotenciación de las instalaciones de bajo voltaje mediante el rediseño eléctrico para mejorar su eficiencia
Authors: Mullo Pallo Mauricio , Segura Flores Roberto , Núñez Villacís Jenny , Trujillo Núñez Ricardo
Published: August 2023

Las instalaciones eléctricas de los centros de educación superior deben cumplir con las normas vigentes para garantizar su calidad y confiabilidad. Las mejoras realizadas incluyeron el diseño de iluminación y tomas eléctricas, con sus respectivos planos y diagramas unifilares de cada tablero eléctrico y protecciones correspondientes. Además, se reemplazó la canalización de la red eléctrica de iluminación y tomacorrientes para permitir una instalación correcta y se mejoró la distribución de energía con nuevas cajas de control. El cálculo lumínico se realizó en una hoja de cálculo y la simulación con el software DIALux para cumplir con los requisitos establecidos en la norma.
Método de clasificación a partir del diagnóstico de calidad morfológica en vivero para la selección de especies forestales promisorias en programas de restauración
Authors: Ureta Leones Diego Armando , García Quintana Yudel , Arteaga Crespo Yasiel , Morales Moreno Arliet , Lazo Pérez Yamila , Jalca Zambrano Ivonne Rocio
Published: August 2023

En la actualidad es cada vez más importante los estudios de calidad morfológica para seleccionar especies de interés forestal cultivadas en vivero que cumplan con los requerimientos biológicos del sitio forestal. El objetivo de este trabajo fue evaluar la calidad morfológica en vivero para la selección de especies forestales promisorias que respondan favorablemente a la restauración de ecosistemas degradados amazónicos. Para ello se realizó un diagnóstico morfológico en vivero, expresado a través de atributos e índices de calidad de seis especies forestales y se empleó un dendrograma jerárquico para clasificar grupos de especies en función de las 11 variables morfológicas analizadas. El diagnóstico morfológico resultó una herramienta viable para los viveristas forestales, lo que permite seleccionar las especies aptas y de mejor calidad para su aclimatación a las disímiles condiciones ambientales. El método de clasificación permitió la formación de tres grupos de especies en función de los atributos e índices de calidad morfológica, el primero conformado por Ocotea quixos y Cedrela odorata, el segundo por Maclura tintoria, Myroxylum balsamun y Ochroma pyramidale y el tercero por Cedrelinga cateniformis. La separación de los grupos estuvo determinada por la mayor de producción de biomasa, grado de lignificación y la baja calidad morfológica. Las especies Cedrela odorata, Cedrelinga cateniformis y Ocotea quixos resultaron de mayor calidad y con condiciones adecuadas a los tres meses de aviveramiento, lo que se reflejará en su respuesta postransplante, capacidad de supervivencia y mayor potencialidad de crecimiento y desarrollo en las condiciones amazónicas.
A crítica de Nietzsche à filosofia de Eduard von Hartmann no contexto das Segunda e Terceira Considerações Extemporâneas
Authors: Soares Daniel Quaresma Figueira
Published: August 2023

Este artigo apresenta a crítica de Nietzsche à filosofia de Eduard von Hartmann no período que abarca as Segunda e Terceira Considerações Extemporâneas. Iniciamos reconstituindo a importância (muitas vezes subestimada) da filosofia hartmanniana no cenário intelectual alemão desse período e apresentando alguns traços centrais de seu sistema. A seguir, passamos à análise da Segunda Consideração Extemporânea, demonstrando o papel da filosofia de Hartmann nessa obra como a ilustração privilegiada de uma tendência nociva diagnosticada por Nietzsche em sua época. Ao final, apresentamos Schopenhauer como educador como um complemento à obra anterior, na medida em que Schopenhauer é tomado como contraexemplo daquela tendência nociva representada por Hartmann
CONSIDERAÇÕES NIETZSCHIANAS ACERCA DE “BARTLEBY, O ESCREVENTE”
Authors: Saavedra Roberta Franco
Published: August 2023

Este artigo se propõe a analisar as interpretações de Giorgio Agamben e Gilles Deleuze acerca do conto “Bartleby, o escrevente” de Herman Melville com especial enfoque nas questões do pensamento de Friedrich Nietzsche trazidas à tona pelos respectivos filósofos. Partindo disso, pretende-se investigar a interpretação deleuziana segundo a qual o personagem Bartleby seria expressão do “nada de vontade” e sua relação com a análise de Nietzsche sobre os ideais ascéticos. Agamben teria partido de outra perspectiva, a saber, do mapeamento da questão ontológica da potência. Nesse sentido, o objetivo é investigar se a apropriação agambeniana do eterno retorno de Nietzsche seria adequada levando em conta os objetivos e estratégias da filosofia nietzschiana.
NIETZSCHE COMO TRANSGRESSOR DA IMANÊNCIA: A POTÊNCIA DO ACASO
Authors: Bittencourt Renato Nunes
Published: August 2023

Resenha da obra BATAILLE, Georges. Sobre Nietzsche: Vontade de Chance. Trad. de Fernando Scheibe. Belo Horizonte: Autêntica, 2017.
CLÉMENT ROSSET ET LE CINÉMA: DEUX OU TROIS CHOSES SUR LE RÉEL
Authors: Larue Thibaut
Published: August 2023

Il s’agira d’inscrire une description de l’expérience cinématographique, à la fois du point de vue du spectateur et du créateur, dans l’horizon plus large de la philosophie de Clément Rosset, à partir d’une sélection de textes qu’il a lui-même consacrés à la question. L’ambition sera double: d’une part, nous nous proposerons d’évaluer l’éventuelle capacité du cinéma à toucher le réel, à en faire voir quelques bribes; d’autre part, et plus généralement, nous tenterons d’esquisser la possibilité d’une esthétique dans l’oeuvre de Rosset, à l’aune du noyau de celle-ci, à savoir la théorie de la singularité du réel et la critique de ses doubles. La finalité de nos recherches sera du même coup dirigée vers une ébauche de définition d’une esthétique tragique, à travers la philosophie rossetienne, l’analyse du cinéma, et la mise en exergue des particularités qui circonscrivent la singularité de celui-ci.
Crítica e clínica na autogenealogia de Nietzsche (1886-8)
Authors: Pacheco Lemos Frederico
Published: August 2023

A proposta deste trabalho é analisar o movimento de releitura que Nietzsche faz de sua própria obra entre os anos 1886 e 1888, comentando os cinco prefácios a obras anteriormente publicadas (escritos em 1886) e o livro Ecce Homo (de 1888). Por essa via, perguntamos se caberia denominar este movimento de uma autogenealogia e problematizamos as possíveis correlações entre uma dimensão crítica  e uma dimensão clínica da filosofia de Nietzsche, por um lado, e entre a vida e a obra do autor, por outro; reavaliando por fim o alcance da tarefa nietzschiana por excelência: transvalorar todos os valores.
« Nous, bons Européens » Le portrait de Pascal esquissé par Nietzsche dans Par-delà bien et mal
Authors: Lebreton Lucie
Published: August 2023

Résumé: Cet article montre les limites de la thèse – fréquemment avancée par lescommentateurs – selon laquelle Nietzsche aimait le très pieux Pascal comme on aimeson grand ennemi. Cette lecture paraît en effet contredite par la première version de lapréface de Par-delà bien et mal, où Nietzsche et Pascal apparaissent luttant contre unennemi commun : « Platon » ou « l’oppression millénaire de l’Église chrétienne ». Noustenterons ainsi de reconstituer le portrait de Pascal qui s’esquisse au fil des pages dePar-delà bien et mal, pour montrer que, loin de le considérer comme un ennemi,Nietzsche voyait en lui l’un de ces « bons Européens » qui lui ont frayé le chemin. Ilapparaîtra en effet que la piété de Pascal était de nature à l’engager dans la voiepérilleuse d’un christianisme qui se surmonte lui-même.
La Esperanto-movado en Tanzanio kaj Togolando
Authors: Goes Heidi
Published: August 2023

Kvankam la afrika Esperanto-movado jam ekzistas dum kelkaj jardekoj, kaj ankaŭ estas pridebatata en la cetera movado, ĝis nun ne ekzistas fidindaj sociologiaj esploroj pri ĝi. Estas la celo de tiu ĉi artikolo vastigi la sciojn pri la strukturo de tiu ĉi juna movado kaj ĝiaj problemoj. La donitaĵoj estas bazitaj sur demandaroj kiuj estis responditaj de esperantistoj en Tanzanio kaj Togolando en aŭgusto–septembro respektive decembro de 1998.
Fungal Identification for Microalgae Biomass Hydrolysis using FTIR
Authors: Ordoñez Morales Sofía Valentina
Published: August 2023

Fungi offer a promising avenue for utilizing residual microalgae biomass after lipid extraction, harboring valuable carbohydrates that can be converted into useful compounds, such as sugars. Fourier Transform Infrared Spectroscopy (FTIR) stands out as an effective and environmentally friendly tool for selecting microorganisms with biotechnological potential. This study utilizes FTIR to identify suitable fungal strains for the hydrolysis of microalgae biomass (Desmodesmus subspicatus and Chlorella sp) post-lipid extraction. Eleven fungal strains are selected, applying FTIR and multivariate analysis to choose filamentous fungi. The maximum cell density is 28.7 × 106 cells mL-1 for Chlorella sp. and 15.8 × 106 cells mL-1 for D. subspicatus, with total carbohydrates of 23.1% and 16.9%, respectively. Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA) are useful for strain identification. Following the analysis, Penicillium G12 stands out for its ability to utilize D. subspicatus biomass, generating glucose and xylose (sugar yields of 9.4% and 6.6% respectively), and Trichoderma auricularis for Chlorella sp. (sugar yields of 12.9% and 9.6% respectively). FTIR proves successful in detecting fungal strains with biotechnological potential.
PENGARUH LINGKUNGAN KELUARGA TERHADAP PENINGKATAN HASIL BELAJAR PENDIDIKAN AGAMA ISLAM
Authors: Jumharis Jumharis , Kamariah Kamariah , Ali Muhammad
Published: August 2023

Penelitian ini adalah suatu jenis penelitian lapangan dengan pokok permasalahannya adalah menggambarkan tentang pengaruh lingkungan keluarga terhadap peningkatan hasil belajar pendidikan agama Islam pada peserta didik di SMA Negeri Bantaeng. Penelitian ini menggunakan metode deskriptif analisis yang didasarkan pada data atau informasi yang diperoleh melalui penelitian sebagai berikut: Field Research yaitu mengumpulkan data-data dengan jalan meneliti langsung ke objek yang bersangkutan (turun ke lapangan) Library Research yaitu mengumpulkan data-data dan fakta-fakta dengan meneliti dari beberapa buku yang berkaitan dengan permasalahan yang dibahas. Populasi dalam penelitian ini adalah seluruh peserta didik pada kelas XI IPS SMA Negeri 1 Bantaeng tahun pelajaran 2013/2014 dengan jumlah peserta didik sebanyak 178 orang. Hasil penelitian menemukan dan mendeskripsikan bahwa lingkungan keluarga berpengaruh pada peningkatan hasil belajar pendidikan agama Islam pada peserta didik di SMA Negeri 1 Bantaeng.
PERAN KOMITE SEKOLAH DALAM MENINGKATKAN MUTU PENDIDIKAN AGAMA ISLAM
Authors: Muhammad Ali  , Jumharis  , Kamariah
Published: August 2023

Penelitian ini bertujuan untuk mendeskripsikan dan menganalisis peran komite sekolah di SMK Negeri 4 Bantaeng, untuk mendeskripsikan dan menganalisis mutu pendidikan agama Islam di SMK Negeri 4 Bantaeng dan untuk mendeskripsikan dan menganalisis peran komite sekolah dalam meningkatkan mutu pendidikan agama Islam di SMK Negeri 4 Bantaeng, baik secara parsial maupun simultan di SMK Negeri 4 Bantaeng. Peneliti menggunakan metode kualitatif dan data dianalisis menggunakan metode deskriptif kualitatif yaitu dengan mendeskripsikan secara menyeluruh data yang didapat selama proses penelitian. Adapun teknik analisis data yang diguanakan dalam penelitian ini adalah teknik analisis deskriptif kulitatif yang bertujuan untuk menggambarkan keadaan atau fenomena yang ada dilapangan yaitu hasil penelitian dengan dipilah-pilah secara sistematis menurut kategorinya dengan menggunakan bahasa yang mudah dicerna oleh semua orang. Adapun hasil penelitian yang didapatkan peneliti tetang peran komite sekolah dalam meningkatkan mutu pendidikan agama Islam di SMK Negeri 4 Bantaeng adalah: (1) Sebagai pemberi pertimbangan (advisory agency), (2) Sebagai badan pendukung (supporting agency, (3) Sebagai badan pengontrol (controling agency) dan (4) Sebagai badan mediator (Executive).
De l’écriture N’Zassa à la métatextualité dans D’éclairs et de foudres de Jean-Marie Adiaffi
Authors: Guehi Germain
Published: August 2023

La parole poétique, tout en servant de vitrine à la manifestation de l’art oratoire dans le milieu traditionnel, transcende, à partir des attributs culturels, l’écriture jusqu’au mélange des genres littéraires dits écriture N’zassa, source de pratique métatextuelle. Un style d’écriture qui fait intervenir dans l’énoncé écrit, les proverbes, le mythe, le conte, le chant, la danse, les sonorités tambourinées, sédiments esthétiques normalement réservés à la production artistique en milieu traditionnel. Cette littérature exige du lecteur, une connaissance des valeurs du terroir de l’écrivain. Comment la poésie N’zassa participe-t-elle de la métatextualité ? Il s’agit de dévoiler, dans le cadre de cette étude, la poésie orale comme étant une essence de l’oralité ; d’analyser les procédés métatextuels dans l’écriture hybride avant d’identifier les enjeux sous-jacents. Grâce aux outils méthodologiques de la sociocritique et de la psychocritique, il ressort que la parole poétique procède de l’oralité ; la métatextualité est présente dans l’énoncé N’zassa à divers degrés ; la pratique fictionnelle développe un double enjeu de construction d’une écriture conforme aux valeurs traditionnelles négro-africaines et de quête de dignité culturelle.
A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
Authors: Yan Chaojun , Xiong Jingjing , Zhou Zirui , Li Qifang , Gao Chuan , Zhang Mengyao , Yu Liya , Li Jinpeng , Hu Ming-Ming , Zhang Chen-Song , Cai Cheguo , Zhang Haojian , Zhang Jing
Published: August 2023

N6-methyladenosine (m6A) methylation of RNA by the methyltransferase complex (MTC), with core components including METTL3–METTL14 heterodimers and Wilms’ tumor 1-associated protein (WTAP), contributes to breast tumorigenesis, but the underlying regulatory mechanisms remain elusive. Here, we identify a novel cleaved form METTL3a (residues 239–580 of METTL3). We find that METTL3a is required for the METTL3–WTAP interaction, RNA m6A deposition, as well as cancer cell proliferation. Mechanistically, we find that METTL3a is essential for the METTL3–METTL3 interaction, which is a prerequisite step for recruitment of WTAP in MTC. Analysis of m6A sequencing data shows that depletion of METTL3a globally disrupts m6A deposition, and METTL3a mediates mammalian target of rapamycin (mTOR) activation via m6A-mediated suppression of TMEM127 expression. Moreover, we find that METTL3 cleavage is mediated by proteasome in an mTOR-dependent manner, revealing positive regulatory feedback between METTL3a and mTOR signaling. Our findings reveal METTL3a as an important component of MTC, and suggest the METTL3a–mTOR axis as a potential therapeutic target for breast cancer.
Transferência de conhecimento na geração de inovação: um olhar para as redes em organizações globais
Authors: Munzlinger André , Gonçalo Cláudio Reis , Dos Santos André Moraes
Published: August 2023

Este artigo possui a finalidade de discutir a literatura sobre a Transferência do Conhecimento e Inovação com o sentido de buscar novas possibilidade de estudos futuros. O resultado permitiu discutir aspectos teóricos, identificar as lacunas do conhecimento e propor a análise de redes de conhecimento para troca de informações como sugestão de estudos futuros em nível intra e inter organizacional. De acordo com o estudo, as redes de inovação possuem um potencial de beneficiar as organizações de forma diferente das propostas analíticas tradicionais, sendo um gerador de insights, e desenvolvedor de novas oportunidades ainda a serem discutidas em trabalhos futuros. Por meio do estudo qualitativo das informações, foi realizada uma análise bibliométrica longitudinal nos últimos 30 anos nas bases de dados Scopus e Web of Science, onde se identificou as principais publicações, autores e clusters específicos. Os softwares NVivo e Vos Viewer auxiliaram no tratamento das informações que facilitaram o entendimento das análises.
Advancing Data-Driven Decision-Making in Smart Cities through Big Data Analytics: A Comprehensive Review of Existing Literature
Authors: Olaniyi Oluwaseun Oladeji , Okunleye Olalekan Jamiu , Olabanji Samuel Oladiipo
Published: August 2023

Governments and cities are increasingly launching smart city (SC) schemes to address the challenges posed by rapid urbanization and population growth in municipalities. Smart cities utilize data from various sources within a metropolis to enhance urban development, promote qualitative lifestyles, and focus on economic and environmental sustainability. Big data analytics (BDA) plays a crucial role in collecting and analyzing vast amounts of data from SC infrastructures, enabling effective management and implementation of smart city initiatives. BDA helps explore data collected through Internet of Things (IoT) devices and sensors, identifying trends, and making appropriate changes, ultimately making smart cities more efficient, sustainable, and beneficial for their inhabitants. However, big data in SC also presents potential risks and challenges related to urban security and the well-being of residents.

The literature review examines various research approaches, techniques, algorithms, and architectures proposed to address the challenges of handling big data in smart cities. Urbanization's growing trend is causing challenges in managing basic amenities and resources in urban areas, necessitating innovative solutions to ensure efficient functioning and improved quality of life for citizens. Previous research has highlighted the significance of big data analytics in driving smart city decision-making, yet many smart city big data initiatives have faced difficulties in implementation. To overcome these challenges, researchers have explored techniques like artificial intelligence, machine learning, data mining, and deep learning, as well as architectures encompassing layers of instrumentation, middleware, and application for end-users. Additionally, researchers have emphasized the importance of selecting appropriate sensors for efficient data collection and explored low-cost smart traffic systems to improve urban traffic management. Overall, this review synthesizes insights from nine scholarly papers, shedding light on approaches to handling big data challenges in smart cities.
Study of Genetic Divergence Using Metroglyph Analysis in Maize (Zea mays L.)
Authors: Likhitha Munukuru , Lal Gaibriyal M.
Published: August 2023

The present trial was carried out at the field experimentation center of the Genetics and Plant Breeding, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, during kharif 2022 to study genetic variability and metroglyph analysis in 21 maize genotypes, including one check variety MAKKA 3 for fifteen quantitative traits. Based on mean performance of 21 genotypes of maize, grain yield per plant was highest in case of VL 183957 (87.8g), VL 19465 (70.26g), VL 183927 (69.6g), VL 19270 (69.2g) genotypes. On the basis of Analysis of variance, significant difference was recorded for all the grain yield and its components indicating presence of large amount of variability in the genotypes. The magnitude of GCV and PCV recorded highest for Days to 50% tasseling and Anthesis-silking interval. High heritability recorded in biological yield per plant, Days to 50% silking, Days to 50% tasseling. High genetic advance was recorded in biological yield per plant, Days to 50% tasseling and cob weight. High genetic advance as percent mean was recorded in Days to 50% tasseling, Anthesis-Silking interval. In metroglyph analysis six complexes are formed, based on biological yield and plant height which were the most variable characters. The maximum index scored by genotype VL-19465 and MAKKA 3 (check) (34) both belongs to complex III and respectively has higher index value for cob weight, grain rows per cob, number of grains per row, 100 seed weight, harvest index, days to 50% tasseling, days to 50% silking, Anthesis-Silking interval, Days to 75% maturity and cob length. Therefore, these two genotypes present in these two complexes should be given priority during selection for maize yield improvement. These genotypes can be crossed to have maximum variability and good combination of characters.
Financial Conflicts of Interest in Public Comments on Medicare National Coverage Determinations of Medical Devices
Authors: Lu Angela , Ji Robin Z. , Ge Alex Y. , Ross Joseph S. , Ramachandran Reshma , Redberg Rita F. , Dhruva Sanket S.
Published: August 2023

This study reviewed public comments for all Medicare National Coverage Determinations between June 2019 and 2022 on select pulmonary and cardiac devices to determine whether financial conflicts of interest were disclosed.
Augmented Reality for Perioperative Anxiety in Patients Undergoing Surgery
Authors: Rizzo Michael G. , Costello Joseph P. , Luxenburg Dylan , Cohen Jacob L. , Alberti Nicolas , Kaplan Lee D.
Published: August 2023

Importance

Both augmented reality (AR) and virtual reality (VR) have had increasing applications in medicine, including medical training, psychology, physical medicine, rehabilitation, and surgical specialties, such as neurosurgery and orthopedic surgery. There are little data on AR’s effect on patients’ anxiety and experiences.

Objective

To determine whether the use of an AR walkthrough effects patient perioperative anxiety.

Design, Setting, and Participants

This randomized clinical trial was conducted at an outpatient surgery center in 2021 to 2022. All patients undergoing elective orthopedic surgery with the senior author were randomized to the treatment or control group. Analyses were conducted per protocol. Data analysis was performed in November 2022.

Intervention

AR experience explaining to patients what to expect on their day of surgery and walking them through the surgery space. The control group received the standard educational packet.

Main Outcomes and Measures

The main outcome was change in State-Trait Anxiety Inventory (STAI) from the screening survey to the preoperative survey.

Results

A total of 140 patients were eligible, and 45 patients either declined or were excluded. Therefore, 95 patients (63 [66.3%] male; mean [SD] age, 38 [16] years) were recruited for the study and included in the final analysis; 46 patients received the AR intervention, and 49 patients received standard instructions. The AR group experienced a decrease in anxiety from the screening to preoperative survey (mean score change, −2.4 [95% CI, −4.6 to −0.3]), while the standard care group experienced an increase (mean score change, 2.6 [95% CI, 0.2 to 4.9]; P = .01). All patients postoperatively experienced a mean decrease in anxiety score compared with both the screening survey (mean change: AR, −5.4 [95% CI, −7.9 to −2.9]; standard care, −6.9 [95% CI, −11.5 to −2.2]; P = .32) and preoperative survey (mean change: AR, −8.0 [95% CI, −10.3 to −5.7]; standard care, −4.2 [95% CI, −8.6 to 0.2]; P = .19). Of 42 patients in the AR group who completed the postoperative follow-up survey, 30 (71.4%) agreed or strongly agreed that they enjoyed the experience, 29 (69.0%) agreed or strongly agreed that they would recommend the experience, and 28 (66.7%) agreed or strongly agreed that they would use the experience again. No differences were observed in postoperative pain levels or narcotic use.

Conclusions and Relevance

In this randomized clinical trial, the use of AR decreased preoperative anxiety compared with traditional perioperative education and handouts, but there was no significant effect on postoperative anxiety, pain levels, or narcotic use. These findings suggest that AR may serve as an effective means of decreasing preoperative patient anxiety.

Trial Registration

ClinicalTrials.gov Identifier: NCT04727697
An open chat with… Sandro Sonnino
Authors: Tsagakis Ioannis , Sonnino Sandro
Published: August 2023

Sandro Sonnino is one of the founding members of the Editorial Board of FEBS Open Bio, having joined in 2011. He is also a member of the Editorial Board of FEBS Letters and is the Editor‐in‐Chief of Glycoconjugate Journal. He is full professor of biochemistry in the School of Medicine at the University of Milan, where he was also formerly coordinator of the Interdisciplinary Laboratory of Advanced Technology (LITA) and Director of the Department of Medical Chemistry, Biochemistry, and Biotechnology. His research is focused on the metabolism and biochemical properties of gangliosides and glycosphingolipids, and their role in cell signaling and the nervous system. He is a guest editor of this special “In the Limelight” issue on glycosphingolipids in disease, which features multiple Reviews and an original research article related to this field. In this interview, Sandro Sonnino discusses the ongoing importance of research on glycosphingolipids and his personal career journey.
Anisotropic Crystal Structure and High Electron Mobility of Novel Ternary Janus P6XY Monolayers (X/Y = S, Se, Te): First‐Principles Examinations
Authors: Vi Vo T. T. , Hoi Bui D. , Nguyen Cuong Q. , Hieu Nguyen N.
Published: August 2023

Recently, by forming a P‐rich P–S system, the P3S monolayer has been predicted to have good resistance to air oxidation, large band gap, high absorption, and superior mobility. Inheriting this prediction, a series of ternary Janus P6XY (X/Y = S, Se, and Te; X ≠ Y) monolayers based on P3X nanosheet are designed and studied. The structures of P6XY monolayers are confirmed to be stable based on the evaluation of calculated results for phonon spectra, ab initio molecular dynamic simulations. It is also found that P6XY compounds possess anisotropic mechanical characteristics. All Janus structures are indirect semiconductors with large energy gaps varying from 2.12 to 2.60 eV calculated by the hybrid functional. Besides, biaxial strain significantly affects the electronic properties of the P6XY monolayers. In particular, the biaxial strains can induce a transition from indirect to direct bandgap in all three P6XY structures. The carrier mobility in the three proposed structures exhibits directional anisotropy and high electron mobility value, up to 1.27 × 103 cm2 V−1 s−1, which are suitable for applications in high‐performance and direction‐dependent nanoelectronic devices.
Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy
Authors: Timm Brennan , Thomson Alice , Bolton Damien , Pether Michael
Published: August 2023

Objective

This study aimed to determine if using a pre‐gerotal fat patch at open partial nephrectomy (PN) as a haemostatic bolster is a viable alternative to using synthetic haemostatic agents.

Materials and methods

Human Research Ethics Committee approval was obtained for audit of a prospectively kept database from July 2012 to July 2021, which followed outcomes of patients who received a low‐tension pre‐gerotal fat patch renorrhaphy at open PN. Patient demographics, intraoperative measures, histological outcomes and post‐operative complications were analysed. Using a retroperitoneal approach, the peritoneum was mobilised and a vascularised pedicle of pre‐gerotal fat was rotated in the direction of the kidney. Routine definition of the hilum, clamping of the hilar vessels and dissection of mass followed. After watertight closure and haemostasis, the harvested pre‐gerotal fat patch was placed over the defect and secured using low‐tension renorrhaphy. Two‐layer closure of the abdominal wall with placement of a drain was routine.

Results

A total of 55 patients underwent open PN. Mean age was 60.4 (35–77) years. There were 38 men and 17 women, and 32 right and 23 left PNs. Mean mass size was 31.9 mm (10–95 mm) and collecting system was breached in 36.5% of cases. One patient (1.9%) suffered a Clavien–Dindo IIIb complication requiring return to theatre and transfusion due to a bleed from an intercostal artery. There were no renal bed bleeds, urine leaks or urine fistulas detected. Mean intraoperative blood loss was 355 mL (50–1500 mL) and mean post‐operative creatinine increased by 10.7 μmol/L (51–172 μmol/L). Mean follow up was 40.2 (4–109) months.

Conclusion

Utilisation of an anatomical pre‐gerotal fat patch to provide pressure at the renorrhaphy site during open PN is an effective technique to assist with surgical haemostasis. This simple technique avoids the costs of haemostatic agents, whilst adding minimal operating time to procedures.
Evaluation of emailed prompts to promote generalization and maintenance of preschool teachers' effective instruction delivery
Authors: Johnson Chelsea N. , Cato Terreca A. , LaBrot Zachary C. , DeFouw Emily R.
Published: August 2023

Young children's noncompliance with adult instructions has the potential to lead to a variety of other internalizing and externalizing difficulties that impact learning, behavior, and overall development. Although a variety of effective intervention strategies exist, early childhood teachers may not be well equipped to consistently implement these strategies to prevent and address young children's noncompliance. Therefore, the purpose of this study was to evaluate the effectiveness and efficiency of a novel teacher implementation support, emailed prompts, to promote early childhood teachers' effective instruction delivery with three children referred for noncompliance and related challenging behaviors. Results indicated that all three teachers increased their accuracy of effective instruction delivery with concomitant improvements in children's response to instructions, including compliance. Furthermore, data suggested that all three teachers spontaneously generalized effective instruction delivery to other non‐referred children in their classrooms. Results, implications, and limitations are discussed.
Hydroelementation and Phosphinidene Transfer: Reactivity of Phosphagermenes and Phosphastannenes Towards Small Molecule Substrates
Authors: Reveley Matthew J. , Feld Joey , Temerova Diana , Yang Eric S. , Goicoechea Jose M.
Published: August 2023

We describe the facile synthesis of [(Me3Si)2CH]2E=PMes* (E=Ge, Sn) from the reaction of the tetrylenes with the phospha‐Wittig reagent, Me3P−PMes*. Their reactivity towards a range of substrates with protic and hydridic E−H bonds (E=N, O, Si) is described. In addition to hydroelementation reactions of the E=P bonds, we show that these compounds, particularly [(Me3Si)2CH]2Sn=PMes*, also act as base‐stabilized phosphinidenes, allowing phosphinidene transfer to other nucleophiles.
Amine Adsorbents Stability for Post‐Combustion CO2 Capture: Determination and Validation of Laboratory Degradation Rates in a Multi‐staged Fluidized Bed Pilot Plant
Authors: Leenders Stefan H. A. M. , Pankratova Galina , Wijenberg John , Romanuka Julija , Gharavi Farahnaz , Tsou Joana , Infantino Melina , van Haandel Lennart , van Paasen Sander , Just Paul‐Emmanuel
Published: August 2023

Alternative to current liquid amine technologies for post‐combustion CO2 capture, new technologies such as adsorbent‐based processes are developed, wherein material lifetime and degradation is important. Herein a robust method to determine degradation rates in a laboratory setup is developed, which was validated with a continuous multi‐staged fluidized bed pilot plant designed to capture 1 ton CO2 per day. An amine functionalized polystyrene adsorbent showed very good agreement between the experimental 1000‐hour laboratory degradation rates and 2200 hours of degradation in a pilot plant. This validates how laboratory experiments can be extrapolated for sorbent screening and for scale‐up. Resulting, the oxidative degradation in the desorber at high temperatures (120 °C) and low O2 concentrations (150 ppmv) is 3 times higher compared to the adsorber at low temperatures and high O2 (56 °C, 7 vol %). Laboratory degradation experiments can hence be used to further optimize process operations to limit degradation or screen for potential new adsorbents.
Robot‐assisted laparoscopic pyeloplasty in the management of lower pole ureteropelvic junction obstruction in a patient with an incomplete duplicated collecting system
Authors: Ueki Hideto , Terakawa Tomoaki , Okamura Yasuyoshi , Bando Yukari , Hara Takuto , Furukawa Junya , Nakano Yuzo , Fujisawa Masato
Published: August 2023

Introduction

The performance of robot‐assisted laparoscopic pyeloplasty has recently been increasing in frequency. However, patients with duplicated renal pelvises and ureters can present challenges.

Case presentation

A 71‐year‐old woman presented with flank pain and was diagnosed with ureteropelvic junction obstruction with an incomplete duplicated collecting system. Preoperative imaging did not reveal the details of the stenosis. Therefore, three reconstructive procedures were prepared: The Anderson–Hynes procedure, end‐to‐side pyeloureterostomy, and upper pole ureter to lower pole pyeloplasty with the Anderson–Hynes procedure for the lower pole. These procedures were determined by the length of the intact ureter and the presence of crossed vessels. During the surgery, the crossing vein was severed, allowing successful reconstruction with Anderson–Hynes anastomosis.

Conclusion

Preoperative evaluation and preparation of multiple surgical techniques are crucial in robot‐assisted laparoscopic pyeloplasty for incomplete duplicated collecting systems.
Comparative studies of immobilized polysaccharide derivatives chiral stationary phases for enantioseparation of furanocoumarins and dihydroflavones and discussion on chiral recognition mechanism
Authors: Tang Luhuan , Chen Yanyan , Wu Mengru , Tang Tingting , Yao Yaqi
Published: August 2023

Enantiomeric separation of furanocoumarins and dihydroflavones compounds were systematically studied in the normal‐phase mode using four different polysaccharide‐type chiral stationary phases, namely, Chiralpak IA, Chiralpak IC, Chiralpak IG, and Chiralpak IK‐3 by high‐performance liquid chromatography. The effect of alcohol modifiers and alcohol content on enantiomeric separation was evaluated for the separation of furanocoumarins and dihydroflavones. All the eight compounds have achieved baseline separation with the resolutions ranging between 1.52 and 23.11. For a better insight into the enantiorecognition mechanisms, thermodynamic analysis was carried out. The mechanisms of chiral recognition have been discussed. Among four chiral columns, Chiralpak IG exhibited the most universal and the best enantioseparation ability toward furanocoumarins and dihydroflavones when used n‐hexane‐isopropanol and n‐hexane‐ethanol as mobile phase, respectively. The steric hindrance, hydrogen bonding, and π‐π interaction played major roles in chiral recognition on Chiralpak IG. By comparing four chiral columns, this work systematically analyzed the separation methods of furanocoumarins and dihydroflavones for the first time and reported some active chiral ingredients of traditional Chinese medicine that have never been separated, which provided a further insight into the enantioseparation of furanocoumarins and dihydroflavones on chiral stationary phases.
Two‐sided markets: The influence of market power on information utilization strategy and welfare
Authors: Cui Zhanhong , Li Kai
Published: August 2023

In the digital age, platforms have leveraged consumer data to discern product preferences, thereby bolstering transaction rates via personalized recommendations. As such, consumer information not only serves as a crucial resource for market expansion but also as a competitive tool for personalized recommendations. Our research explores the strategic application of consumer information by dual‐sided platforms, within the context of two upstream merchants vending identical goods. We scrutinize the decision‐making process of these platforms in three distinct scenarios, examining their propensity to utilize consumer information for personalized recommendations, and the subsequent ramifications on pricing, consumer surplus, and social welfare. Our findings suggest a tendency among platforms to exploit consumer information, thereby inducing merchants to adopt a standardized pricing strategy through adjusted commissions. However, when a significant disparity in platform strengths is present, the more dominant platform is inclined to elevate commission levels, leading to discriminatory pricing by merchants. Interestingly, our study reveals that on platforms where information utilization and pricing strategies are optimally balanced, consumer surplus escalates in tandem with the intensification of inter‐platform competition. In contrast, total social welfare diminishes with increased competition. This research offers valuable insights into the strategic use of consumer information by platforms, with significant implications for pricing strategies, consumer surplus, and social welfare.
Controlled damping ethylene‐vinyl acetate copolymer/styrene ethylene butylene styrene foam in wide temperature range prepared by supercritical nitrogen
Authors: Yu Zhen , Wang Cong , Zhang Xin , Zhao Yongxian , Wen Shibao , Zhang Zhen Xiu
Published: August 2023

Herein, ethylene‐vinyl acetate copolymer/styrene ethylene butylene styrene (EVA/SEBS) blend foam with wide effective damping temperature range (ΔT) was prepared via supercritical nitrogen. The influence of the ratio of EVA and SEBS on the foaming and damping properties was studied. ΔT gradually widened into the high temperature region with the increase of SEBS content, and higher SEBS gave denser and more uniform cell structure and reduced the density of the blend foam. When the content of SEBS was 40 phr, the density of the blended foam was 0.185 g/cm3, and the ΔT was −3~54°C. These damping foams were lightweight and this work showed that damping performance could be controlled by simply adjusting blend content, which is of great significance to broaden the application environment of damping materials.

Highlights

EVA/SEBS foam was prepared by supercritical nitrogen.

EVA and SEBS blends can broaden the damping temperature range.

The damping temperature range was −3.0~54.6°C when SEBS content was 40 phr.
An Efficient Synthesis of Benzimidazole‐pyrazines via the Sequential Ugi/Hydroamination/Cyclization Reactions
Authors: Tahmasebi Behnam , Adib Mehdi , Mahdavi Mohammad , Taslimi Parham
Published: August 2023

This study reported an efficient two‐step method based on the sequential post‐Ugi hydroamination reaction for synthesizing a novel class of benzimidazole‐pyrazines with high yields. First, a Ugi fourcomponent reaction (Ugi‐4CR) is carried out using readily available starting materials, i. e., 1H‐benzo[d]imidazole‐2‐carboxylic acid, aldehydes, propargylamine, and isocyanides, in methanol at ambient temperature. Afterward, the Ugi products undergoes a sequential intramolecular hydroamination/cyclization reaction between a nitrogen of imidazole and alkyne functional group in aqua media in the presence of AuCl3 as a catalyst to obtain benzimidazole‐pyrazine products. These heterocyclic compounds may have a potential to be utilized in designing modern drugs with desirable features.
The Media in Southern Europe: Continuities, Changes and Challenges
Authors: Papathanassopoulos Stylianos , Giannouli Iliana , Archontaki Ioanna
Published: August 2023

The media systems of Portugal, Spain, France, Italy, Malta, Greece, Cyprus and Turkey represent what Daniel Hallin and Paolo Mancini have proposed as the Southern European or polarised pluralistic model. Regardless of their differences, the media in Southern Europe are characterised by low levels of newspaper circulation, a tradition of advocacy reporting, instrumentalisation of privately owned media, politicisation of public broadcasting and broadcast regulation and limited development of journalism as an autonomous profession. In the digital era, the media in Southern Europe have to adjust themselves to the new conditions, as citizens have turned rapidly to the digital and social media, regardless the uneven development of the Internet in most countries. It seems that digitisation of the media landscape has led the Southern European media to follow a path not very dissimilar to other European countries as in the past. The advent of digital and social media, as well as the emergence of citizen journalism, has made the news media landscape even more uncertain for the legacy media and the professional journalist, but less controlled by the state, which used to be the norm in the analogue past.
Wissensstand und Fehlvorstellungen zu Vorsorgedokumenten – Ergebnisse einer Bürgerbefragung
Authors: Fleischmann Carolin , Henking Tanja , Neuderth Silke
Published: August 2023

Einleitung

Vorsorgedokumente wie Patientenverfügung oder Vorsorgevollmacht sind bedeutsame Instrumente der Vorausplanung für Situationen, in denen ein Mensch nicht mehr für sich selbst entscheiden kann. Obwohl immer mehr Bürger:innen in Deutschland solche Dokumente erstellen, ist über ihr Wissen zu Zweck, Arten und Anwendung von Vorsorgedokumenten wenig bekannt. Nach über 10 Jahren seit der gesetzlichen Verankerung der Patientenverfügung soll diese Studie das Wissen von Bürger:innen erfassen und Wissenslücken detektieren.

Methoden

In der Stadt und im Landkreis Würzburg wurde 2021 eine Querschnittsbefragung von volljährigen Bürger:innen u. a. zu Besitz, Umgang mit und Wissensstand zu Vorsorgedokumenten durchgeführt. Die Rekrutierung erfolgte über Werbeanzeigen und lokale Netzwerke.

Ergebnisse

Von den 282 Befragten (MAlter = 50 J., zu 2 Drittel weiblich) hatten 43,4 % nach Selbstangabe zumindest ein Vorsorgedokument verfasst. Im Wissenstest wurden im Mittel 22/34 Punkten erreicht. Fragen zur konkreten Anwendung von Vorsorgedokumenten anhand eines Fallbeispiels sowie zu Sterbehilfearten wurden häufig korrekt beantwortet, wohingegen beim Faktenwissen zu den einzelnen Dokumenttypen größere Wissensdefizite bestanden. Objektiv getestetes Wissen und Variablen zum subjektiven Wissensstand korrelieren positiv.

Diskussion

Die relativ hohe Quote an erstellten Dokumenten in dieser Stichprobe ist Ausdruck ihrer raschen Verbreitung in den letzten Jahren. Das Wissensniveau ist als niedrig einzuschätzen und zeigt Fehlvorstellungen zu Rechten und Pflichten der verfassenden Person sowie der beteiligten Akteure. Das gemessene Wissen der Bürger:innen steht in Diskrepanz zum häufig geäußerten Wunsch, durch informiertes Erstellen von Vorsorgedokumenten ihre Selbstbestimmung zu wahren.
Grain yield and adaptation of spring wheat to Norwegian growing conditions is driven by allele frequency changes at key adaptive loci discovered by genome-wide association mapping
Authors: Mroz Tomasz , Dieseth Jon Arne , Lillemo Morten
Published: August 2023

Key message

Adaptation to the Norwegian environment is associated with polymorphisms in the Vrn-A1 locus. Historical selection for grain yield in Nordic wheat is associated with TaGS5-3A and TaCol-5 loci.

Grain yields in Norwegian spring wheat increased by 18 kg ha−1 per year between 1972 and 2019 due to introduction of new varieties. These gains were associated with increments in the number of grains per spike and extended length of the vegetative period. However, little is known about the genetic background of this progress. To fill this gap, we conducted genome-wide association study on a panel consisting of both adapted (historical and current varieties and lines in the Nordics) and important not adapted accessions used as parents in the Norwegian wheat breeding program. The study concerned grain yield, plant height, and heading and maturity dates, and detected 12 associated loci, later validated using independent sets of recent breeding lines. Adaptation to the Norwegian cropping conditions was found to be associated with the Vrn-A1 locus, and a previously undescribed locus on chromosome 1B associated with heading date. Two loci associated with grain yield, corresponding to the TaGS5-3A and TaCol-5 loci, indicated historical selection pressure for high grain yield. A locus on chromosome 2A explained the tallness of the oldest accessions. We investigated the origins of the beneficial alleles associated with the wheat breeding progress in the Norwegian material, tracing them back to crosses with Swedish, German, or CIMMYT lines. This study contributes to the understanding of wheat adaptation to the Norwegian growing conditions, sheds light on the genetic basis of historical wheat improvement and aids future breeding efforts by discovering loci associated with important agronomic traits in wheat.
Utilization of by-products for preparation of Pickering particles
Authors: Muiz Abdul , Klojdová Iveta , Stathopoulos Constantinos
Published: August 2023

The processing of foods yields many by-products and waste. By-products are rich in bioactive components such as antioxidants, antimicrobial substances, polysaccharides, proteins, and minerals. A novel use of by-products is as materials for the preparation of Pickering particles. Pickering particles are considered appropriate materials for the stabilization of emulsions. Conventionally, emulsions are stabilized by the addition of stabilizers or emulsifiers which decrease the surface tension between phases. Emulsifiers are not always suitable for some applications, especially in foods, pharmaceuticals, and cosmetics, due to some health and environmental problems. Instead of emulsifiers, emulsions can be stabilized by solid particles also known as Pickering particles. Pickering emulsions show higher stability, and biodegradability, and are generally safer than conventional emulsions. Particle morphology influences emulsion stability as well as the potential utilization of emulsions. In this review, we focused on the by-products from different food industries (cereal and dairy) that can be used as materials for preparing Pickering particles and the potential of those Pickering particles in stabilizing emulsions.