bluuebunny/crossref_metadata_2025 huggingface dataset:
ПОТЕНЦИАЛ К ДИФФЕРЕНЦИРОВКЕ МЕЗЕНХИМАЛЬНЫХ СТРОМАЛЬНЫХ КЛЕТОК ПРИ РЕПЛИКАТИВНОМ СТАРЕНИИ
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Ratushnyy A.Yu. , Buravkova L.B. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: September 2022

Mesenchymal stromal/stem cells (MSCs) are capable of multilinear differentiation and participate in tissue homeostasis including the remodeling and reparation processes. With aging these cells more and more often activatesenescence (cell aging) that alters cell functions and microenvironment which can be the reason for age-related pathologies. One of the features of senescent MSCs is thought to be a decline of multipotency that may limit their reparative functions in tissues. The paper presents a study of the MSCs osteogenic and adipogenic potential during replicative senescence. A decline of the MSCs adipogenic potential was associated with downregulation of PPARG,(a key transcription regulator of adipogenesis). There was evidence of reciprocal increasing of the osteogenic potential even though the several positive osteogenesis regulators (BMP2, BMP6, IGF1, IL1B) were downregulated. Besides, during differentiation matrix calcification was enhanced and osteoprotegerin concentration increased that can be an issue in context of atherosclerotic plaques calcification in elder people. Expression of key osteogenesis regulator RUNX2 and markers SPARC, SPP1, COL1A1, BGLAP remained stable during replicative senescence of MSCs.
Ortaokul Fen Bilimleri Ders Kitaplarında Yer Alan STEM Etkinliklerinin Yeterliliklerinin İncelenmesi
Authors: Uyanık Sibel , Özakdağ Aynur , Yıldırım Mehtap
Published: September 2022

21.yüzyıl gereklilikleri doğrultusunda yeniden yapılandırılan Fen Bilimleri Öğretim Programı’nda öğrencilerin problemlere disiplinler arası bakış açısıyla bakması hedeflenmiştir. Ders kitaplarındaki etkinliklerin bu doğrultuda hazırlanmış olması önem taşıdığından çalışmada ders kitaplarındaki STEM etkinliklerinin ünite, kazanım, öğrenme ortamı, etkinlik içeriği, STEM konu alanı ve STEM alanlarında gelişim bakımından incelenmesi amaçlanmıştır. Çalışmada durum çalışması deseni kullanılmıştır. Araştırmada doküman inceleme amacıyla “STEM Etkinlikleri Değerlendirme Rubriği” kullanılmıştır. Bununla birlikte ortaokulda fen bilimleri STEM etkinliklerini yüz yüze ve çevrimiçi uygulayan 10 öğretmenin görüşleri alınmıştır. Ders kitaplarında yer alan STEM etkinliklerinin en az bir kazanım ile ilişkili olduğu, etkinliklerin yapısal olarak bir ortaklık taşımadığı görülmüştür. Çoğu etkinliğin bir problem durumuna sahip olmadığı, alternatif çözümler sunmadığı, en az bir STEM disiplinin eksik olduğu, ürün odaklı ve değerlendirme bakımından yetersiz olduğu belirlenmiştir. Bu doğrultuda ders kitaplarındaki STEM etkinliklerinin ortak bir yapıda, alan yazında yer alan STEM etkinliklerine ait özellikleri barındıracak ve alternatif ölçme araçlarını içerecek biçimde yeniden düzenlenmesi önerilmiştir.
Concentración de nitritos en mortadela industrial producida en Honduras y distribuida en Tegucigalpa
Authors: Barahona Nilda , Alvarado Maylin , Núñez Clara , Riera Ana
Published: September 2022

Los aditivos alimentarios son la base de la industria alimentaria en la conservan y prolongan la vida en almacén de los alimentos. El objetivo de este estudio fue analizar la concentración de nitrito de sodio (NaNO2) presente en la mortadela industrializada y comercializada en Tegucigalpa, Honduras de agosto a diciembre de 2019. Estudio cuantitativo, descriptivo, no experimental y transversal. Se recolectaron un total de 3 muestras de mortadela para cada uno de los 16 lotes obtenidos de 6 empresas hondureñas productoras de embutidos para un total de 48 muestras. La recolección de información fue mediante el Instrumento para la recolección de información-cuestionario y el método analítico de la Association of Official Analytical Chemists (AOAC, por sus siglas en inglés) 973.31 ambos aplicado a cada muestra. La cuantificación de nitrito obtenida en comparación con los criterios del Reglamento Técnico Centroamericano y la norma general del Codex oscila entre una concentración mínima y máxima de 34.32 ± 3.66 mg/kg y 106.32 ± 8.17 mg/kg, respectivamente. De esto se concluye que el grado de cumplimiento en un 100% (48) según la regulación nacional mientras que en un 56.25% (27) según el Codex (nivel máximo de uso recomendado en 80 mg/kg).

Palabras clave: Nitritos, Mortadela, Embutidos, Carne Procesada (Carne Industrializada), Aditivos Alimentarios, RTCA, Codex.
Molecular characterization of endophytic fungi from pine (Pinus oocarpa) in Honduras
Authors: Ortiz Bryan , Enríquez Lourdes , Mejía Karla , Yanez Yensi , Sorto Yuliana , Guzman Sayda , Aguilar Kateryn , Fontecha Gustavo
Published: September 2022

Pine is one of the important coniferous genera in America. In Honduras, Pinus oocarpa is the most critical conifer species since it plays an essential role for the country's economy and represents a symbol of national identity. Endophytic fungi are defined as microorganisms that reside in the internal tissues of plants without causing any obvious immediate negative effects and are an integral part of their associated microbial communities. This study aimed to isolate and characterize the endophytic fungi present in the pines of Honduras through the amplification and sequencing of the ribosomal RNA gene's internal transcribed spacer (ITS). A total of 7 pines from the department of El Paraíso in eastern Honduras were analyzed. A total of 14 fungi grouped into 6 genera and 7 species were isolated: Fusarium lateritium, F. pseudocircinatum, Pestalotiopsis pini, P. microspora, Xylaria grammica, Trichoderma atroviride, y Nigrospora oryzae. To our knowledge, this is the first report of endophytic fungal species in pines in Honduras. Although some endophytic fungi may be mutualistic or saprophytic, the present study shows the presence of several genera of endophytic fungi that have been reported as pine pathogens. The presence of these fungi in the pines of Honduras represents a potential threat to the health of the forest. Further research is needed to increase knowledge about the importance of these fungi and the potential impact they could have on pine forests in Honduras.
Keywords: Endophytic fungi, Pinus oocarpa, Honduras
Enseñanza de la Radiología Oral durante el COVID-19 en Honduras: Transición al Modelo Híbrido
Authors: Flores-Girón Hazaria , Paz Claudinne , Paz-Maldonado Eddy
Published: September 2022

La pandemia COVID-19 ha obligado a generar cambios en los modelos pedagógicos empleados en la enseñanza de la Radiología Oral. Esto ha ocasionado nuevas y mayores exigencias a los docentes, principalmente en las universidades públicas de Honduras que desarrollan su práctica formativa mediante una educación tradicional 1. El modelo híbrido fue implementado como una alternativa para continuar avanzando en los procesos de enseñanza-aprendizaje 2. Dicho modelo combina los componentes virtual y presencial 3, lo que hace posible el desarrollo de la enseñanza de la Radiología Oral.
Reinhold Fritzgaertner y los reportes de fósiles de Honduras a finales del siglo XIX
Authors: Zúniga Leonel E. , Aguilar-Armijo David
Published: September 2022

Durante el siglo XIX el Gobierno de Honduras propició la llegada de académicos extranjeros, siendo el geólogo y paleontólogo alemán Reinhold Fritzgaertner uno de los casos más notorios por su influencia en el impulso de la actividad minera en Honduras, sin embargo, se ha descrito muy poco su rol en la historia de la paleontología de América Central. A través de una extensa revisión documental en bibliotecas virtuales de Europa y América, en el repositorio virtual Tzibalnaah-UNAH y en el Archivo Nacional de Honduras, se buscó determinar los vínculos académicos de Reinhold Fritzgaertner y su aporte en la investigación de la paleontología de Honduras en el siglo XIX. Fritzgaertner llega a Honduras después de completar sus estudios de doctorado bajo la asesoría del renombrado geólogo y paleontólogo alemán Friedrich August von Quenstedt y de fungir como asistente del renombrado geólogo y paleontólogo norteamericano James Hall, manteniendo vínculos con importantes instituciones académicas de la época. Su presencia en Honduras trascendió la minería y desarrolló un papel notorio en la historia de la ciencia de este país, en una época en que la evidencia paleontológica de Honduras adquirió importancia en el mundo académico. Fritzgaertner puede ser considerado el académico que tuvo el mayor conocimiento de la paleontología de Honduras en el siglo XIX, y mediante su participación en las diferentes exposiciones mundiales, los reportes en medios escritos de divulgación y sus vínculos académicos internacionales, propició el reporte de fósiles de Honduras a finales del siglo XIX.

Palabras clave: Paleontología, América Central, Historia de Honduras, Exposiciones mundiales.
Coffee’s Melanoidins. A critical review of contemporary scientific literature
Authors: Portillo Ostilio R. , Arévalo Ana C.
Published: September 2022

Melanoidins are brown pigments thermally generated during the non-enzymatic Maillard reaction and are present in a large number of baked and roasted food products (e.g., bakery products, dark beer, coffee, etc.), conferring their typical color and improving their appearance, which is usually considered, by the end-consumer, as an indicator of quality; After all, quality is in the eye of the beholder.

The amount of melanoidins varies depending on the precursors’ concentration and the type of processing to which a given food product is submitted (baking time + temperature). Additionally, melanoidins have been in our diets for millennia, not only improving the organoleptic qualities of food but also exerting a great array of physiological benefits directly linked to their chemical composition, molecular conformation, and structural size.

Aside from their prebiotic effects, melanoidins also display other beneficial properties, among which the most salient are their antioxidant capacity, antibacterial and chelating activities, and anticancer action. However, regardless of the plethora of in vitro experimental evidence that validates the properties mentioned above, there is still controversy about their significance for human health since many of these properties seem to be associated with high molecular weight melanoidins, which, because of their size, cannot cross the intestinal wall suggesting their action is relegated to the intestinal tract where after being fermented and fragmented are finally converted in a series of metabolic derivatives some of which manage to cross into the bloodstream while others are simply excreted through the feces.

The following is a synthesis collected from the available scientific literature which aims to elucidate several aspects of melanoidins (i.e., synthesis, determination, metabolism, & biological activity) to create awareness about their importance for human health and provide information about where to find them to improve our diets.

Keywords: Synthesis, fractionation, separation, antioxidant activity.
Desempeño del sistema de vigilancia COVID-19 en Honduras 2020: Análisis de la ley de Benford
Authors: Valladares Wendy , Bayardo Cabrera José
Published: September 2022

El COVID-19 es una enfermedad infecciosa responsable hasta la fecha de 6,369,703 muertes a nivel mundial. Para poder controlarla es importante adaptar y reforzar los sistemas nacionales de salud y ampliar las capacidades en materia de vigilancia, siendo el reporte diario de nuevos casos y muertes por COVID-19, una de las principales herramientas para comprender y dar respuesta a la pandemia. El trabajo se centró en identificar inconsistencias en los datos reportados sobre casos y muertes confirmadas de COVID-19, por el sistema de salud hondureño durante el año 2020. Se analizaron los datos oficiales publicados entre el 11 de marzo y el 31 de diciembre de 2020, por el centro de recursos coronavirus de la Universidad Johns Hopkins, los datos fueron divididos en cuatro segmentos de análisis, el primero correspondió a los primeros 50 días de pandemia en el país, el segundo incluyó datos hasta el 24 junio, el tercero hasta el 1 diciembre y el cuarto incluyó todos los datos del 2020. Para el análisis se hizo uso de la ley de Benford, el cual es un fenómeno estadístico ampliamente usado que permite detectar datos anómalos en los sistemas de vigilancia de cada país. Hasta el 31 de diciembre el sistema de salud hondureño confirmó 121,827 casos positivos y 3,130 muertes por COVID-19 en Honduras. Respecto a la detección de datos anómalos el segundo segmento de análisis obtuvo un mejor resultado, sin embargo, se observo que el análisis acumulado correspondiente al 2020 no se ajustó a la Ley de Benford. En general, la vigilancia tuvo una mejoría en el desempeñó después de los primeros 50 días de pandemia, no obstante, los datos referentes al 2020 revelan una disconformidad con la ley de Benford, lo que se interpreta como un desempeño de notificación no adecuado.

Palabras clave .COVID-19, distribuciones estadísticas, Honduras, monitoreo epidemiológico, notificación de enfermedades.
Nursing Home Admission Predictors Based on Administrative Claims and Electronic Health Records: A Scoping Review (Preprint)
Authors: Han Eunkyung , Kharrazi Hadi , Shi Leiyu
Published: September 2022

BACKGROUND

Older adults account for the largest percentage of the long-term care (LTC) and total medical spending. Prior studies have identified several data sources and many predictors for nursing home admission among the elderly [5]-[10]; however, such studies have often used data sources with limited availability across large populations and methods with widely disparate sample populations. Insurance claims and electronic health records (EHR) are widely available across large populations of older adults. Predictors extracted from insurance claims or EHR data can be extremely useful for predicting nursing home admission among older adults on a population scale.

OBJECTIVE

This study is to synthesize previous findings and to identify advances and gaps in the recent literature on predictors of nursing home admission that are collected from insurance claims or EHRs.

METHODS

To report the study selection, PRISMA extension for scoping reviews (PRISMA-ScR) guidelines were used.

RESULTS

A total of 27 papers were selected for final inclusion in this review. In most studies, mean or average age of total sample ranged from 70 to 79 years (n=15, 56%). In addition to nursing home admission, all-cause mortality (n=12; 32%) and hospitalization/ rehospitalization (n=7; 19%) were frequently used as outcome measures. In the selected studies, 33.0%(n=9) used Cox proportional hazard models while 30.0%(n=8) used logistic regression models. Comorbidity counts, frailty, cognitive function, medication, medical and social service utilization were used as predictors of nursing home admissions using EHR and insurance claims data.

CONCLUSIONS

Prediction tools based on EHRs or claims data may assist clinicians and patients to make informed decision. Future studies should develop discussion on how to adapt the predictive models of nursing admissions in healthcare systems.
Intellectual Agent Ensemble with Professional Competencies, Pattern Recognition and Decision Making
Authors: Bryndin Evgeny
Published: September 2022

Each competence is exercised by an intellectual agent with a competent functional professional image. Intellectual agents form an ensemble with clever ethical artificial intelligence. The use of an ensemble with intelligent ethical artificial intelligence in various environments is carried out by synergistically adjusting the interaction of intelligent agents based on data from a specific environment obtained by an analytical competent intellectual agent. Modeling holographic processes of the human psyche based on artificial intelligence of machine learning with Fourier transformation using full parametric sequences of necessary and sufficient data of holograms of target objects solves the problem of their unambiguous detection in different environments and in different conditions. An ensemble of intelligent decision-making agents is a cognitive information system that makes a decision based on an objective analysis of available data in difficult situations, in an interactive mode, taking into account performance criteria and resource-time constraints. Decision-making criteria are functionalities that express preferences and allow ranking the quality of decisions. Decisions are made on the basis of rules. Decision rules are a set of logical constructs used to produce a decision based on criteria, data, and knowledge. An ensemble of intellectual agents with professional competencies, pattern recognition and decision-making fully model the abilities of the human psyche.
Revisiting Sarita as Sita: A Comparative Study of Vijay Tendulkar’s Kamala
Authors: M. Gayatri Dr.
Published: September 2022

Vijay Tendulkar, the frontline of Indian theatre, is well known for sensitising his audience and readers of the dogmas of this cultural society. The social order , once framed are discerning the women as the weaker sex and eventually trapping the rights levered in the name of social structure weaved by the myth. Though engrossed with a pack of Indian nobility , femininity portrayed in the myths like the Ramayana often show the fragility loaded in abundance in the female protagonist- Sita. Thus while portraying the character of Sarita, Tendulkar intentionally or naively has brought out the character of Sita to the view of his audience. This research article is an attempt to bring out the magnetized but feebly tabulated character of Sarita by Vijay Tendulkar in his play Kamala.
Las cuatro falacias de la evolución cultural popular
Authors: Sarabia López Saúl , García Campos Jonatan Yair
Published: September 2022

Objetivo: revisar si las críticas comúnmente hechas a la psicología evolucionista, ejemplificadas como las cuatro falacias de la psicología evolucionista popular, pueden ser aplicadas al programa de evolución cultural.   Método: se sigue el método propio de la filosofía, es decir, el análisis conceptual y la consistencia lógica de los argumentos.   Resultados: el programa denominado evolución cultural, en la versión que revisamos, es un programa de evolución cultural popular porque comparte las mismas críticas hechas a la psicología evolucionista popular.  Limitaciones: futuros trabajos deben evaluar si realmente las críticas a la psicología evolucionista son correctas, y si dichas críticas afectarían del mismo modo tanto a la psicología evolucionista popular como al programa de evolución cultural popular.  Principales hallazgos: la psicología evolucionista popular y el programa de evolución cultural popular comparten las siguientes afirmaciones centrales: a) los mecanismos cognitivos, y distintivamente humanos, que permiten la propagación y estabilidad de la cultura son fijados y heredados genéticamente; b) las circunstancias en las que nuestra especie evolucionó nos proveen varias ideas heurísticas para formular hipótesis acerca de cómo funcionan nuestras mentes y cuerpos en la actualidad; y c) los componentes básicos de la mente son antiguos en términos evolutivos.
A Review of Modern Computer Networks
Authors: Vishvakarma Tanmya
Published: September 2022

Abstract: A computer network's principal role is to facilitate the transfer of digital information between computers. An interconnected network of computer equipment is all that constitutes a computer network. Distributing tasks among different machines is frequent in a computer network. Most networks confront substantial threats from attacks on their resources. This research focuses on computer networks. It is only through the establishment of a computer network that this is made possible at all. Nodes include things like computers, cell phones, servers, and other networking gear. Computer networks enable the Internet, as well as the shared use of application and storage servers, printers, and fax machines. Through the use of computer networks, many jobs can be completed. Systems can be classified as open or closed. If you want to connect to the network, the open system is ready to go. Closed systems, on the other hand, require further authentication to connect to other networks.
Cross-Domain Deterrence in the Cyber World
Authors: Lambi Amit , Agarwal Rashmi , Vijayaraghvan Sandeep
Published: September 2022

Abstract: Cyber Space, like outer space, is strategically a vital domain for state offence and defence. However, there has been a substantial rise in the sponsored cyber activities to inflict heavy losses to critical infrastructures due to the lack of rules or norms or any strict international regulations to govern the conflicts in cyberspace. This activity affects the national defence strategies when oppressed by the response crisis and hugely impacts the risk factors. In these circumstances, the dilemma is whether any operative or offensive choice in the event of a cyber threat or cyber-attack violates international law. War has always been a last resort when other forms of punishment have failed, but the power dynamic has fundamentally shifted since World War II. State Governments have been hoarding the arsenals that could destroy cities in a second; hence a need for unconventional resolution has led to the evolving nature of deterrence. States must reconsider alternate strategies to protect their sovereignty by implementing cross-domain deterrence that can cripple an adversary economy, swift surgical strike as retaliation, or curb the attack using counterintelligence. The threat landscape in Cyber Space is beyond frontiers, and the consequences cannot be contained at the perimeter by the regular armed forces. Require special forces and strategies to mitigate the risks. Cross-Domain deterrence to increase cyber resilience, it is crucial to identify existing strategy disparities to take necessary actions on the state misconduct and the misconduct of a policy for global cooperation during state-sponsored cyberattacks. This paper discusses the evolving framework by assessing the changing threat landscape and its associated risks.
Stability of invertible, frustration-free ground states against large perturbations
Authors: Bachmann Sven , De Roeck Wojciech , Donvil Brecht , Fraas Martin
Published: September 2022

A gapped ground state of a quantum spin system has a natural length scale set by the gap. This length scale governs the decay of correlations. A common intuition is that this length scale also controls the spatial relaxation towards the ground state away from impurities or boundaries. The aim of this article is to take a step towards a proof of this intuition. We assume that the ground state is frustration-free and invertible, i.e. it has no long-range entanglement. Moreover, we assume the property that we are aiming to prove for one specific kind of boundary condition; namely open boundary conditions. This assumption is also known as the "local topological quantum order" (LTQO) condition. With these assumptions we can prove stretched exponential decay away from boundaries or impurities, for any of the ground states of the perturbed system. In contrast to most earlier results, we do not assume that the perturbations at the boundary or the impurity are small. In particular, the perturbed system itself can have long-range entanglement.
Periodically refreshed quantum thermal machines
Authors: Purkayastha Archak , Guarnieri Giacomo , Campbell Steve , Prior Javier , Goold John
Published: September 2022

We introduce unique class of cyclic quantum thermal machines (QTMs) which can maximize their performance at the finite value of cycle duration τ where they are most irreversible. These QTMs are based on single-stroke thermodynamic cycles realized by the non-equilibrium steady state (NESS) of the so-called Periodically Refreshed Baths (PReB) process. We find that such QTMs can interpolate between standard collisional QTMs, which consider repeated interactions with single-site environments, and autonomous QTMs operated by simultaneous coupling to multiple macroscopic baths. We discuss the physical realization of such processes and show that their implementation requires a finite number of copies of the baths. Interestingly, maximizing performance by operating in the most irreversible point as a function of τ comes at the cost of increasing the complexity of realizing such a regime, the latter quantified by the increase in the number of copies of baths required. We demonstrate this physics considering a simple example. We also introduce an elegant description of the PReB process for Gaussian systems in terms of a discrete-time Lyapunov equation. Further, our analysis also reveals interesting connections with Zeno and anti-Zeno effects.
Designing the Quantum Channels Induced by Diagonal Gates
Authors: Hu Jingzhen , Liang Qingzhong , Calderbank Robert
Published: September 2022

The challenge of quantum computing is to combine error resilience with universal computation. Diagonal gates such as the transversal T gate play an important role in implementing a universal set of quantum operations. This paper introduces a framework that describes the process of preparing a code state, applying a diagonal physical gate, measuring a code syndrome, and applying a Pauli correction that may depend on the measured syndrome (the average logical channel induced by an arbitrary diagonal gate). It focuses on CSS codes, and describes the interaction of code states and physical gates in terms of generator coefficients determined by the induced logical operator. The interaction of code states and diagonal gates depends very strongly on the signs of Z-stabilizers in the CSS code, and the proposed generator coefficient framework explicitly includes this degree of freedom. The paper derives necessary and sufficient conditions for an arbitrary diagonal gate to preserve the code space of a stabilizer code, and provides an explicit expression of the induced logical operator. When the diagonal gate is a quadratic form diagonal gate (introduced by Rengaswamy et al.), the conditions can be expressed in terms of divisibility of weights in the two classical codes that determine the CSS code. These codes find application in magic state distillation and elsewhere. When all the signs are positive, the paper characterizes all possible CSS codes, invariant under transversal Z-rotation through π/2l, that are constructed from classical Reed-Muller codes by deriving the necessary and sufficient constraints on l. The generator coefficient framework extends to arbitrary stabilizer codes but there is nothing to be gained by considering the more general class of non-degenerate stabilizer codes.
Multistability for a Mathematical Model of the Dynamics of Predators and Preys in a Heterogeneous Area
Authors: Ha T. D. , Tsybulin V. G.
Published: September 2022

We consider the system of reaction-diffusion-advection equations describing the evolution of the spatial distributions of two populations of predators and two prey populations. This model allows us to consider directed migration, the Holling functional response of the second kind, and the hyperbolic prey growth function. We obtain conditions on the parameters under which cosymmetries exist. As a result, multistability is realized, i.e., the one- and two-parameter families of stationary solutions appear. For a homogeneous environment, we analytically derive explicit formulas for equilibria. With a heterogeneous habitat, we computed distributions of species using the method of lines and the scheme of staggered grids. We present the results of violation of cosymmetry and transformation of the family in the case of invasion of a predator.
Knowledge, Attitude and Practices Regarding Simplified Kundalini Yoga Among College Students in Tamilnadu
Authors: Periasamy Panneerselvam , Suganthi Vajiravelu , Gunasekaran Sasikala
Published: September 2022

Simplified Kundalini Yoga (SKY) is a physical, mental and spiritual discipline for developing strength, awareness, character, and consciousness. Simplified physical exercises, simplified Kundalini meditation, Kayakalpa practice, and introspection are its components. Health professionals consider yoga for skeletal symptoms, followed by psychological and physical ailments. Stress is a common issue for college students during their undergraduate studies. Short-term yoga has been proven to help pupils feel less stressed. The purpose of this study was to evaluate college students' knowledge, attitudes and practice of (KAP) Simplified Kundalini Yoga. A secondary objective was to compare KAP among medical, paramedical and non-medical students in Tamilnadu, India. A cross-sectional web-based online survey among the medical, paramedical and non-medical students were conducted. A semi-structured questionnaire using a non-probability volunteers sampling technique was used in this study. There were 323 responses in total: 101 medical students (40 males and 61 females), 100 paramedical students (19 males and 81 females), and 122 non-medical students (1 male and 121 females). All participants were given a pre-tested questionnaire about their awareness, attitudes, and practices related to SKY. The data collected were entered in MS Excel and presented in tables and graphs. Significant results were subjected to tests of significance like the Chisquare test at a 5% level of significance. In general, only 6.5% of them have adequate knowledge scores, 26 % of them have a good level of attitude score, and 8.7% of them have a good level of practice score. More than 80-90% of students lack knowledge, attitude and practice of SKY. Reasons for not taking up yoga were mainly lack of interest, laziness and poor time management. The study concluded that students have a positive outlook towards simplified Kundalini yoga but need motivation.
Stakeholder engagement strategies assessment in expanded public works programme
Authors: Best Andisile , Yalezo Bhasela
Published: September 2022

South Africa has evolved and defeated a blemished past of apartheid before 1994. Even after 27 years of democracy, South Africa has been struggling to stabilise economic markets with continued control by the white minority that marginalised the black community. The unemployment rate in the Province of the Eastern Cape in South Africa has grown from 28.5% in 1993 to 45.8% in quarter 3 of 2020 (ECSECC, 2020). Set targets have not been met since 2018, with programmes implemented not attractive nor conducive for the targeted youth and persons with disabilities. The study critically evaluated the existence and the extent of stakeholder management strategies in the Expanded Public Works Programme (EPWP) within the Eastern Cape Department of Transport and the effects of not meeting the set youth and persons with disabilities targets over the years. To gain lived experiences of beneficiaries, a case study of the household Contractor Programme was used in three districts through group semi-structured interviews with non-probability purposive sampling used to select respondents using a primary data collection instrument. Data received was analysed with themes using a descriptive analysis approach to narrate the lived experiences of participants within EPWP. Results revealed a need for improved stakeholder diversity and inclusion, communication with stakeholders, management oversight, policy guidance, monitoring and evaluation within EPWP projects.
BRAFV600E testing for low-risk papillary thyroid microcarcinomas -- Computational model from a patient-oriented approach
Authors: Tessler Idit , Leshno Moshe , Feinmesser Gilad , Cohen Oded , Feinmesser Raphael , Alon Eran , Avior Galit
Published: September 2022

Background: Given the good prognosis of low-risk papillary thyroid
microcarcinomas (lrPTMCs) accurate risk stratification is valuable to
optimize management: active surveillance vs. surgery. BRAFV600E testing
was associated with increased recurrence risk, hence AS seems reasonable
for mutation-negative lrPTMC. However, when considering AS, patient
perception is highly important as adherence and emotional aspects are
challenging. In this study, we aimed to model the contribution of
BRAFV600E testing for the management of PTMCs when tailored to the
patient perspective. Methods: We developed a Markovian model to predict
the role of BRAFV600E in prioritizing between hemithyroidectomy (HT) and
active surveillance (AS) for lrPTMCs. We used a simulated cohort of
lrPTMCs, with probabilities of each strategy driven from previous
literature. Outcomes were measured as quality-of-life years (QALYs).
One- and two-way sensitivity analyses were conducted to ascertain model
robustness. Results: We found that the optimal strategy (e.g., that
would maximize QALYs) varies according to BRAFV600E status for patients
without a preset predilection between AS to HT. Using one-way
sensitivity analysis, we found that the two main variables that have the
strongest impact on the decision are the utility of AS and the utility
of a disease-free state after HT. Two-way sensitivity analysis
demonstrated that BRAFV600E status can define the optimal strategy for
patients in the middle zone of the utility range (e.g., patients without
clear preference). Conclusions: Our model suggests that BRAFV600E status
can facilitate decision-making regarding AS vs. HT for patients without
preset predilection. Our model supports further real-life studies of
BRAFV600E testing for PTMCs.
Long time behavior of solutions for time-fractional pseudo-parabolic equations involving time-varying delays and superlinear nonlinearities
Authors: Lân Đỗ , Tran Van Tuan
Published: September 2022

We study the long time behavior of solutions for time-fractional
pseudo-parabolic equation involving time-varying delays and nonlinear
pertubations, where the nonlinear term allows to have a superlinear
growth. Concerning the associated linear problem, we establish a
variation of parameters formula of mild solution and prove some
regularity estimates of resolvent operators. In addition, thanks to
local estimates on Hilbert scales, fixed point arguments and a new
Halanay type inequality, we obtain some results on the global
solvability, stability, dissipativity and the existence of decay
solutions to our problem.
A simple transeptal approach versus the conventional left atrial approach for mitral valve procedures: retrospective cohort study.
Authors: Allam Beshoy , Mostafa Mohammed Mahmoud , Elminshawy Ahmed , Ayoub Mahmoud Thabet
Published: September 2022

Background: Having good exposure to the mitral apparatus during mitral
valve replacement is a vital decision every cardiac surgeon must take.
This study was conducted to compare the Simple Transseptal approach and
the conventional Left Atrial approach for mitral valve procedures, to
evaluate the safety and efficacy of the simple transseptal approach
during open-heart mitral valve procedures, as the conventional left
atrial approach may not provide optimal exposure, especially in
unfavorable anatomical and operative situations. Methods: This is a
retrospective chart review cohort study. It has been conducted on 140
patients who were diagnosed with heart diseases that required mitral
valve replacement. Surgeries were performed in Cardiothoracic Surgery
Department at Assiut University Hospital over the period from January
2016 to June 2021 by one surgeon. Mitral procedure was done through
median sternotomy incision under general anesthesia on cardiopulmonary
bypass machine with cold antegrade cardioplegia. Demographic data,
preoperative diagnosis, intraoperative findings, hospital stay,
complications, and mortality were documented and revised. Results: one
hundred and forty patients were enrolled in this study with a median age
of 39 years, and no significant differences as regards the baseline
demographic data as age, sex, and BMI. 68 patients underwent mitral
valve replacement through the simple transseptal approach and 72
patients through the conventional left atrial approach. Both studied
groups had insignificant differences as regards bypass time,
re-operation rate, postoperative complications, hospital stay, and
mortality. Conclusion: Simple transseptal approach through the midpoint
of fossa ovalis could be a safe and even favorable alternative to the
traditional left atriotomy approach in certain difficult operative
situations during mitral valve replacement surgery.
Toxigenic potential of Alternaria species from cereals
Authors: Bagi Ferenc , Ilicic Renata , Jevtic Radivoje , Orbovic Branka , Savic Zagorka , Suman Michele , Tóth Beáta , Berėnyi Attila , Popovic Tatjana
Published: September 2022

Toxigenic potential of four and one isolate of A. alternata and A.
tenuissima, respectively, on durum wheat cultivar Dusan (Triticum durum L.)
and common wheat cultivar Barbee (T. vulgare L.) were tested. Three
different wheat / isolate genotype combinations were used for artificial
inoculation of grains under laboratory conditions and toxins production.
Alternaria toxins alternariol (AOH), alternariol monomethyl ether (AME),
tentoxin (TEN), tenuazonic acid (TeA) and altenuen (ALT) concentrations
were determined by LC-MS/MS. Cultivar Barbee proved to be a more suitable
substrate for toxin production, whereby AOH, AME and TeA were present in
highest concentrations. These results underline the possibility of fungal
infection and mycotoxin production by Alternaria species in field and under
storage conditions. Further research is needed for official regulation of
ac?ceptable levels of Alternaria mycotoxins in food and feed.
Uso etnobotánico de Psidium guajava en tres estados de México
Authors: Mex Álvarez Rafael Manuel de Jesús , Alcocer Bastos Mario Hernán , Sánchez Andrade Juana Elizabeth , Carreras Contreras Ricardo
Published: September 2022

El objetivo de este trabajo es recuperar los saberes que la población de tres estados de la república mexicana (Campeche, Estado de México y Yucatán) posee sobre la Psidium guajava como planta medicinal. Se realizó un estudio transversal en el cual se aplicaron encuestas sobre el conocimiento etnobotánico de la guayaba. Las encuestas etnobotánicas realizadas demuestran que el uso de plantas medicinales para el tratamiento de enfermedades respiratorias, incluida la covid-19, es una costumbre popular y frecuente; entre las plantas mencionadas destaca Psidium guajava porque tradicionalmente se ha asociado a la mejoría de los síntomas respiratorios de la tos, gripa o asma debido a sus propiedades antimicrobianas.
Effects of job stressor on psychological well- being among the nurses at hospital during pandemic covid-19
Authors: P.M Anthony , Aren Merikan , R Vincent Balang
Published: September 2022

As a result of the recent pandemic, the psychological wellbeing among nurses can be overlooked despite anecdotally it has greatly affect nurses’ wellbeing. Hence, this study aimed to identify the effects of job stressors on the psychological wellbeing among nurse in the hospital during pandemic COVID-19. This study also to identify the effects of job stressors on the autonomy, environmental mastery, personal growth, positive relations with others, purpose in life, self-acceptance among the nurses.  Random sampling was used to select 128 nurses were  who were working in the hospital were randomly selected. The respondents were asked to complete a questionnaire using Google Form via online. The Work Stress Scale and Ryff’s Psychological Well-Being Scale (PWBS) were used to test the hypotheses of the study. The dataset was analysed by using Statistical Package for The Social Sciences (SPSS), Version 25. The result showed that there were significant negative effects of job stressors on psychological wellbeing. The results also indicated that the job stressors have positive impact on autonomy and self-acceptance among nurses. Hence, the stakeholder should take appropriate and effective measures to minimize the impact of job stressors and increase the level of psychological wellbeing among nurses. The findings of the study have reflected an important and beneficial implication to the health care sector of Malaysia in producing more capable nurses and ready to face any challenge during pandemic.
Detection of Highway Lane using Color Filtering and Line Determination
Authors: Erwin Iwan Muhammad , Prajitno Dicky Rianto , Prakasa Esa
Published: September 2022

Traffic accidents are generally caused by human error as a driver. The main cause is that the vehicle shifts away from the driving lane without the driver realizing it. Usually, because the driver is sleepy or drunk. Therefore, it is necessary to have a system that functions to assist the driver's navigation to stay on the correct driving path, such as a driver assistance system (DAS). In this system, the driving lane detector is the main part. This system serves to assist the driver's navigation to stay on the correct driving path. Vehicles are installed with cameras to record video towards the road ahead. Computers are also installed for image processing, identifying left and right road lines, and forming ego-lane. This paper offers an image processing-based method for recognizing driving lanes and presenting visualizations in real-time. This method has been tested using a data set, that video driving on Indonesian highway on the Cipali and Palikanci sections using dashboard camera. The test results obtained an accuracy of 99.25%.
Representasi Pola Komunikasi Keluarga dalam Lagu ‘Bertaut’ Karya Nadin Amizah
Authors: Lukietta Nabilla Zachra
Published: September 2022

Musik adalah media kesenian yang digunakan untuk mengungkapkan atau mengekspresikan perasaan dan pandangan hidup seseorang. Seseorang menggunakan musik untuk menyampaikan pendapatnya atau curahan hati pribadi hingga sebuah kritik sosial melalui lirik lagu yang dilengkapi dengan video klip. Salah satu lagu tentang curahan hati pribadi seseorang adalah ‘Bertaut’ karya Nadin Amizah yang berhasil menarik perhatian khalayak dan memenangkan beberapa penghargaan. Hingga kini, ‘Bertaut’ masih menduduki chart platform musik walaupun telah rilis setahun yang lalu. Penelitian ini bertujuan untuk mengetahui dan menganalisis representasi pola komunikasi keluarga yang terjadi dalam lagu ‘Bertaut’ karya Nadin Amizah menggunakan Semiotika Roland Barthes. Jenis penelitian ini adalah kualitatif deskriptif menggunakan paradigma kritis, dianalisis menggunakan Semiotika Roland Barthes dan dibantu dengan Teori Sudut Pandang atau Standpoint Theory karya Sandra Harding dan Julia T. Wood. Penulis menggunakan Studi Pustaka untuk mengumpulkan data dengan cara mencari sumber literatur baik buku, berita, artikel, atau kepustakaan lain, lalu informasi yang didapat diobservasi dan didokumentasikan. Hasil penelitian menjelaskan bahwa pada video klip lagu ‘Bertaut’ karya Nadin Amizah ditemukan adanya denotasi, konotasi, dan mitos tentang representasi pola komunikasi keluarga. Lagu tersebut menceritakan tentang bagaimana seorang ibu single parent berjuang untuk menjaga keluarga dan memenuhi kebutuhan hidupnya. Terjadi pembagian tugas antara anggota keluarga dan saling memegang kontrol dalam kewajibannya masing-masing. Sehingga pola komunikasi yang digambarkan lagu ‘Bertaut’ karya Nadin Amizah adalah Pola Komunikasi Seimbang Terpisah.
Strategi Selebgram Dalam Membangun Personal Branding Melalui Pengelolaan Akun Instagram
Authors: Mita Tiara
Published: September 2022

Selebgram is currently widely used as a promotional media carried out by a brand because it is considered effective in promoting a product that is packaged in its own way so that it looks more natural. Celebrity is also considered as a tool in building the image of a brand or service. Personal branding is the process of how individuals are seen as a brand by their target market, personal branding is aimed at attracting more clients who actively shape public perceptions. In determining the strategy to be carried out, the researcher uses the concept of personal branding according to Peter Montoya. In addition, this study also uses the theory of communication privacy management to see how celebrities manage their personal information on their Instagram account. This study uses a descriptive qualitative research approach. The data collection technique in this study was to conduct direct field observations, namely to conduct direct interviews with research informants to obtain data about the personal branding of celebrities in managing personal information on their Instagram accounts. The results of the study show that celebrities in building personal branding have their own privileges according to the content they choose. Celebrities in managing privacy information in general already know the limits of their privacy information with the public on social media, so they understand what information can and cannot be shared on their social media. They have good management, between themselves and netizens.
Analisis Framing Berita Kebakaran Hutan dan Lahan pada Tribunpekanbaru.Com dan Goriau.Com
Authors: Ardhana Delvy , Ismandianto Ismandianto
Published: September 2022

Kebakaran hutan dan lahan merupakan bencana yang terjadi hampir setiap tahun  di Indonesia, terutama di Provinsi Riau. Upaya dan solusi terus dilakukan oleh pemerintah guna mencegah kebakaran hutan dan lahan melalui gerakan “2020 Riau Bebas Karhutla”. Penelitian ini membahas framing pemberitaan kebakaran hutan dan lahan di Riau pada media online lokal Tribunpekanbaru.com dan GoRiau.com periode Januari-Februari 2020 dengan menggunakan analisis framing model Robert N. Entman. Hasil penelitian menunjukkan bahwa kebakaran hutan dan lahan di Riau dibingkai secara berbeda. Media online Tribunpekanbaru.com membingkai kasus-kasus kebakaran hutan dan lahan yang terjadi di Riau dan mengungkapkan tersangka pembakaran hutan dan lahan. Sementara itu, media online GoRiau.com menghadirkan kerangka yang berbeda, media ini lebih menonjolkan sisi humanis pemerintah dalam upaya mengatasi bencana kebakaran hutan dan lahan. Perbedaan dalam segi penulisan berita dimotivasi oleh perbedaan dalam perspektif masing-masing media untuk menarik minat pembacanya. Dalam hal ini terlihat dari bagaimana jurnalis menulis berita yang disusun berdasarkan elemen Entman yaitu identifikasi masalah, diagnosa kasus, penilaian moral, dan solusi yang ditawarkan.