bluuebunny/crossref_metadata_2025 huggingface dataset:
Drug Repurposing: An Emerging Tool for Drug Reuse, Recycling and Discovery
Authors: Roy Supriya , Dhaneshwar Suneela , Bhasin Bhavya
Published: February 2021

Drug repositioning or repurposing is a revolutionary breakthrough in drug development
that focuses on rediscovering new uses for old therapeutic agents. Drug repositioning can be
defined more precisely as the process of exploring new indications for an already approved drug
while drug repurposing includes overall re-development approaches grounded in the identical
chemical structure of the active drug moiety as in the original product. The repositioning approach
accelerates the drug development process, curtails the cost and risk inherent to drug development.
The strategy focuses on the polypharmacology of drugs to unlocks novel opportunities for logically
designing more efficient therapeutic agents for unmet medical disorders. Drug repositioning also
expresses certain regulatory challenges that hamper its further utilization. The review outlines the
eminent role of drug repositioning in new drug discovery, methods to predict the molecular targets
of a drug molecule, advantages that the strategy offers to the pharmaceutical industries, explaining
how the industrial collaborations with academics can assist in the discovering more repositioning
opportunities. The focus of the review is to highlight the latest applications of drug repositioning in
various disorders. The review also includes a comparison of old and new therapeutic uses of repurposed
drugs, assessing their novel mechanisms of action and pharmacological effects in the management
of various disorders. Various restrictions and challenges that repurposed drugs come
across during their development and regulatory phases are also highlighted.
Surface irregularities in titanium marine parts formed by the particulate injection moulding process
Authors: Ewart Paul , Mangan Kieran , Ahn Seokyoung , Capek Lukas
Published: February 2021

In this study, a structural hold down component was designed and produced using the particulate injection moulding (PIM) process. The material of choice was titanium due not only to the material properties but also due to the desire to create custom-made components for a state-of-the-art marine vessel, Earthrace 2.On removal from the mould, the green parts were seen to have an irregular surface on the top face. Known as surface bloom, it can be seen during moulding of single-phase commodity polymers as a result of changes in the polymer density, due to shear stresses and irregularities of turbulent flow.Literature suggests the surface bloom is a result of a separation between the two phases, but the preliminary findings show little evidence of this within the sectioned profile. The sintered parts were sectioned, and inspection of the surfaces was done using metallographic techniques. The use of CAD models enabled the defect to be modelled and the models provided a more likely scenario. It was further confirmed that there were no through part defects present and although the surface irregularities were caused by separation of the two-phases, the effect was restricted to the outer surface of the parts.
Conceptualizations of Cyberchondria and Relations to the Anxiety Spectrum: Systematic Review and Meta-analysis (Preprint)
Authors: Schenkel Sandra K , Jungmann Stefanie M , Gropalis Maria , Witthöft Michael
Published: February 2021

BACKGROUND

Cyberchondria describes the detrimental effects of health-related internet use. Current conceptualizations agree that cyberchondria is associated with anxiety-related pathologies and may best be conceptualized as a safety behavior; however, little is known about its exact underlying mechanisms.

OBJECTIVE

This systematic review and meta-analysis aims to give an overview of the conceptualizations of cyberchondria and its relation to anxiety-related pathologies, quantify the strength of association to health anxiety by using meta-analyses, highlight gaps in the literature, and outline a hypothetical integrative cognitive-behavioral model of cyberchondria based on the available empirical evidence.

METHODS

A systematic literature search was conducted using PubMed, Web of Science, and PsycINFO electronic databases. A total of 25 studies were included for qualitative synthesis and 7 studies, comprising 3069 individuals, were included for quantitative synthesis. The meta-analysis revealed a strong association of cyberchondria (r=0.63) and its subfacets (r=0.24-0.66) with health anxiety.

RESULTS

The results indicate that cyberchondria is a distinct construct related to health anxiety, obsessive-compulsive symptoms, intolerance of uncertainty, and anxiety sensitivity. Further studies should distinguish between state and trait markers of anxiety-related pathologies and use experimental and naturalistic longitudinal designs to differentiate among risk factors, triggers, and consequences related to cyberchondria.

CONCLUSIONS

Health-related internet use in the context of health anxiety is best conceptualized as health-related safety behavior maintained through intermittent reinforcement. Here, we present a corresponding integrative cognitive-behavioral model.

CLINICALTRIAL
Understanding the determinants of digital health marketing strategies: a comparison of private and public sector hospitals (Preprint)
Authors: Dailah Hamad
Published: February 2021

BACKGROUND

The use of traditional media and technologies have increased the challenges for public health education and awareness, especially in public hospitals. Despite the importance of social and digital technologies for health promotion, the level of adoption and execution is relatively slow in public hospitals.

OBJECTIVE

The present study aims to understand how organizational resources and technology selection as well as structure and culture can influence health-marketing strategies in both public and private hospitals.

METHODS

The study adopts the interpretivist research paradigm and a social constructivist approach to understand individual, organizational, government, structural, financial and cultural factors that can influence the formulation and implementation of health marketing strategies. The study has chosen health professionals and other employees from four public and private hospitals as sources of data.

RESULTS

The findings reveal that private hospitals have a flat structure and high levels of employee empowerment which enhance collaboration, coordination, skills development, and technology use. The use of social and digital media is common, which increases word of mouth, patient awareness and education, patient engagement and feedback, user generated content and social influence for private hospitals. Conversely, government control and centralization, cost leadership strategy, traditional media and technologies as well as limited resources and human capital are some of the challenges which complicate advanced health marketing practices.

CONCLUSIONS

There is limited literature available regarding the determinants of health marketing strategies for public and private hospitals. The present study explores the strengths that enhance health marketing practices in private hospitals. In addition, the study highlights the challenges of public hospitals which negatively influence advanced health marketing practices and performance outcomes. The study provides a number of recommendations for the health ministry, management in hospitals, and health promotion departments with the purpose of advancing health marketing practices.
Cost–effectiveness analysis of empagliflozin compared with glimepiride in patients with Type 2 diabetes in China
Authors: Salem Ahmed , Men Peng , Ramos Mafalda , Zhang Yan-Jun , Ustyugova Anastasia , Lamotte Mark
Published: February 2021

Aim:
The study assesses the cost–effectiveness of empagliflozin versus glimepiride in patients with Type 2 diabetes and uncontrolled by metformin alone in China, based on the EMPA-REG H2H-SU trial.
Materials & methods:
A calibrated version of the IQVIA Core Diabetes Model was used. Cost of complications and utility were taken from literature. The Chinese healthcare system perspective and 5% discounting rates were applied.
Results:
Empagliflozin+metformin provides additional quality-adjusted life-years (0.317) driven by a reduction in the number of cardiovascular and renal events, for an additional cost of $1382 (CNY9703) compared with glimepiride+metformin.
Conclusion:
Empagliflozin is cost-effective treatment versus glimepiride applying a threshold of $30,290 (CNY212,676).
Las elecciones presidenciales en EEUU 2012-2016. Un estudio comparativo desde una perspectiva estatal e individual
Authors: Ortega Ortiz Reynaldo Yunuen , Pacheco Muñoz Ma. Edith
Published: February 2021

En este artículo nos preguntamos: ¿Cuál fue la capacidad explicativa de la desigualdad y la pobreza en el ámbito estatal en las elecciones presidenciales de Estados Unido en 2012 y 2016? ¿Cuál fue el balance estatal en las elecciones presidenciales en Estados Unidos? Y exploramos a nivel individual, utilizando la “American National Election Studies Survey”, ¿qué variables nos ayudan a entender el voto en favor de los candidatos presidenciales republicanos en 2012 y 2016? Así, para contestar nuestras preguntas realizamos dos análisis, uno, en el ámbito estatal, y otro, a partir de los votantes, con el fin de explicar los resultados contrastantes de 2012 y 2016.
Fanny Hill, la pornografía y la novela sentimental: el eslabón faltante en la gesta de la novela inglesa dieciochesca
Authors: Deanda-Camacho Elena
Published: February 2021

Este artículo analiza la manera en la cual la novela inglesa Fanny Hill (1748) de John Cleland sintetiza el idealismo cervantino, propio de la novela sentimental, y el realismo, heredero de la picaresca femenina. Al situar esta obra en la gesta de la novela dieciochesca inglesa, especialmente frente a las obras de Samuel Richardson y en constante diálogo con el legado picaresco y cervantino, Fanny Hill emerge como una novela compleja, metaficticia y reflexiva. En su reflexividad, Cleland se enfoca en analizar los mecanismos de la novela en general y de la novela pornográfica en particular. Los mecanismos que se destacan son la reflexión sobre el ejercicio literario, el registro lingüístico y la recepción. Sobre todo, Fanny —como “narradora”— se detiene a analizar con detalle el savoir faire de la novela pornográfica en la cual el tema central del sexo, en cuanto mecánico y repetitivo, exige una narrativa mecánica y repetitiva. Finalmente, el artículo destaca la complicada agencia simbólica, literaria, económica y de género, que despliega la “narradora” Fanny ante otras protagonistas de la novela inglesa, como Pamela o Clarissa. Al enfatizar la síntesis que la novela hace del idealismo y del realismo, así como su constante reflexividad, arguyo que Fanny Hill debe ser considerada más que una obra exclusivamente pornográfica y entrar en el canon de la novela inglesa del dieciocho.
Evaluasi Aplikasi Mobile Jaminan Kesehatan Nasional (JKN) di Kota Malang Ditinjau Dari Aspek Usability
Authors: Annisa Nur , Pradana Dharma Surya , Suharso Wildan
Published: February 2021

Untuk meningkatkan pelayanan terhadap peserta Jaminan Kesehatan Nasional, BPJS Kesehatan meluncurkan aplikasi mobile JKN. Aplikasi mobile JKN merupakan bentuk transformasi digital model bisnis BPJS Kesehatan, yang semula berupa kegiatan administratif di kantor cabang atau fasilitas kesehatan, kini ditransformasi ke dalam bentuk aplikasi yang dapat digunakan untuk mempermudah peserta dimana saja kapanpun tanpa batasan waktu. Kemudahan dalam mengakses aplikasi jkn merupakan pengaruh dari usability yang ada. Tingkat usability dapat menentukan sejauh mana sebuah aplikasi dapat digunakan pengguna untuk mencapai tujuannya dan seberapa mudah dalam menggunakan antarmuka apikasi tersebut. Dan pada penelitian ini dilakukan penilaian pada aplikasi mobile Jaminan Kesehatan Nasional (JKN) karena masih terdapat kekurangan yang ada pada system seperti adanya fungsionalitas yang masih belum berjalan sesuai dengan fungsinya sehingga membuat pengguna kurang puas ketika menggunakan aplikasi JKN. Pengujian ini dimulai dengan mengevaluasi aspek usability melalui pengujian kegunaan (usability testing) untuk mengetahui seberapa besar kepuasan pengguna dalam berinteraksi dengan aplikasi. Untuk penilaian tersebut digunakan tools Software Usability Measurement Inventory (SUMI)¸berdasarkan efficiency, affect, helpfulness, control dan learnability pengujian ini menggunakan aplikasi SPSS. Dari hasil penelitian lima variabel yang ada tiga diantaranya memiliki nilai yang masih rendah yaitu efficiency, control dan learnability  sehingga menunjukan bahwa tingkat usability yang ada pada aplikasi masih rendah dan belum memenuhi kepuasan pengguna aplikasi.
Wireless Sensor Network Monitoring Suhu, Kelembaban, Getaran dan Bau dengan Sistem Pentransmisian MQTT
Authors: Jamaluddin Ahmad Fahri , Risqiwati Diah , Setiawan Sumadi Fauzi Dwi
Published: February 2021

Memelihara burung merupakan salah satu hobi masyarakat Indonesia. Kebutuhan gizi dan nutrisi berupa protein pada burung dapat diperoleh dari suatu makanan salah satu makanan burung kroto atau telur semut rangrang. Pada budidaya semut rangrang, suhu dan kelembaban dapat mempengaruhi semut rangrang dalam bertelur. Masalah yang dihadapi saat ini pada budidaya semut rangrang adalah peternak tidak dapat memperkirakan kondisi suhu dan kelembaban. Mereka hanya memperkirakan suhu dan kelembaban dengan merasakan panas di dalam ruangan. Adapun masalah lain yang dihadapi adalah adanya getaran dan bau kimia di sekitar toples tempat semut rangrang di budidaya yang dapat membuat semut stress dan dapat menurunkan hasil produksi kroto. Dari permasalahan ini dilakukan penelitian dengan membuatan model pengatur suhu, kelembaban, getaran dan bau kimia dapat dimanfaatkan untuk menggunakan mikrokontroler Arduino UNO, sensor DHT11, sensor SW-420 dan sensor MQ-02 pada ruang budidaya semut rangrang dengan menggunakan system pentransmisian MQTT (Message Queuing Telemetry Transport). Alat ini akan mempermudah budidaya untuk mengatur nilai suhu, kelembaban, getaran dan bau kimia di dalam ruang budidaya tersebut. Alat ini menggunakan mist maker sebagai alat penghasil uap dan buzzer sebagai alarm secara otomatis agar budidaya semut rangrang stabil dan menghasilkan produksi kroto yang berkualitas. Hasil penelitian ini menunjukkan bahwa jarak mempengaruhi kuat sinyal dan delay atau selisih waktu transmisi data yang mana pada jarak 5m sampai jarak 7m sinyal semakin melemah dan rata-rata selisih waktu transmisi data betambah sekitar 5.1 sec hingga 5.9 sec. Hasil penelitian ini juga menunjukkan bahwa sistem pentrasmisian MQTT yang menggunakan ESP8266 memiliki rata-rata jumlah packet loss secara keseluruhan sebesar 35%.
Analisa Performansi Controller Pada Arsitektur Jaringan Software Defined Network(SDN)
Authors: Rahmawan Agung Dwi , Syaifuddin Syaifuddin , Risqiwati Diah
Published: February 2021

Software Defined Network (SDN) merupakan sebuah konsep pendekatan baru dalam jaringan untuk mendesain, membangun serta mengelola suatu jaringan komputer. Konsep ini melakukan pemisahan terhadap Data Plane dan Control Plane. Dalam konsep SDN ini terdapat suatu komponen penting yang bertanggung jawab terhadap segala aturan dalam pengelolaan dan pendistribusian informasi terhadap seluruh perangkat jaringan yaitu Controller. Karena peran Controller yang penting maka performa dari Controller perlu diuji sehingga dapat mengetahui kemampuan dari Controller yang digunakan. Dalam penelitian ini dilakukan perbandingan analisis nilai Quality of Services (QoS) terhadap implementasi SDN menggunakan Controller Floodlight dan Ryu dengan menjalankan topologi linear dan mesh dalam jumlah Switch yang beragam mulai dari 4, 8, 12 dan 16 Switch. Selama pengujian berlangsung dari node sumber ke node tujuan yang sama juga dialiri variasi background traffic mulai dari 50 hingga 200 Mbps.  Hasil yang didapatkan yaitu Controller Ryu memiliki nilai QoS yang lebih baik dari floodlight pada semua topologi yang diujikan, nilai latency dan jitter pada floodlight lebih tinggi dari ryu serta cenderung meningkat pada traffic 100 Mbps Pada throughput, ryu memiliki nilai lebih tinggi dengan kisaran 856-933 Kbps. Sedangkan pada packet loss floodlight lebih tinggi sementara ryu hanya memiliki rata-rata packet loss sebesar 0,5%. Namun pada pengujian hanya pada jumlah switch, floodlight menjamin dalam tingkat respons serta pengelolaan data yang besar di dalam arsitektur jaringan SDN.
MEMUPUK KEBERAKSARAAN: BERINOVASI DALAM PERSPEKTIF BELAJAR SEPANJANG HAYAT
Authors: Mustakim Mustakim , Sulistiono Eko , Saripah Iip , Dinni Fahmi
Published: February 2021

Many studies have suggested the relationship between innovation and lifelong learning that are interrelated. However, it is still difficult to find research that takes the viewpoint of innovation as an implication of a lifelong learning process which cultivates literacy. By collecting conceptual literatures on innovation and lifelong learning, this article aims to provide a perspective view of the concept of lifelong learning in innovation. This article also contributes to encourage adults to have the mindset to always learn without being limited by space and time in creating innovation so as to avoid being illiterate again. The findings of this article suggest the idea that innovation can create learning processes. Even in the learning process, it can have implications for innovation. In the future research requires a significant amount of time to examine various perspectives and conceptual issues related to innovation seen in the perspective of lifelong learning.
Pregnancy with Suspected Pulmonary Arterial Hypertension: A Referral for Confirmation Prior to Termination of Pregnancy
Authors: Schwartz Cody , Jain Neeraj , Ali Murtuza , Falco Viviana
Published: February 2021

Certain cardiovascular conditions pose a significant maternal-fetal risk
during pregnancy with the greatest risk seen in pulmonary arterial
hypertension (PAH). Current guidelines clearly recommend the avoidance
of pregnancy in women with PAH and termination when pregnancy does occur
but only after the diagnosis of PAH has been confirmed by right heart
catheterization (RHC).
Giant exophytic Marjolin`s ulcer of the lower leg after the gunshot wound
Authors: Vulovic Dejan , Stankovic Vesna , Sarenac-Vulovic Tatjana , Milosevic Bojan , Vulovic Maja , Radovanovic Dragce , Spasic Marko
Published: February 2021

Introduction. Marjolin?s ulcer is a skin malignancy that occurs on a scar or chronic wound. It most commonly occurs on a burn scar. Squamous cell carcinoma is the most common type of this tumor in more than 90% of cases. The rate of this rare malignant transformation is 1?2%. Marjolin?s ulcer is more aggressive than other skin cancers. Wide excision is the treatment of choice. Recurrences are common. We present a large exophytic carcinoma of the lower leg as a rare form of this tumor ac-cording to the size and type together with reconstruction results. Case report. A 52-year-old man was presented with a large exophytic tumor on the left lower leg. The tumor was located at the site of the previous gunshot in-jury. The latent period was 22 years. Tumor size was 14 ? 12 cm. Wide excision was performed (2-cm surgical margin), including the deep fascia, and the defect was closed by a split-thickness skin graft from the opposite thigh. Histology showed well-differentiated squamous cell carcinoma. There were no regional or distant metastases. One year after surgery, there was no recurrence of the tumor. Conclusion. Early diagnosis of Marjolin?s ulcer and wide excision are mandatory. Surgical margins for excision should be 2 cm, and excision should include deep fascia. Multiple and repeated biopsies of chronic wounds are advised. There is no consensus on the staging of Marjolin?s ulcer and lymph node dissection.
Type 1 Diabetes Management With Technology: Patterns of Utilization and Effects on Glucose Control Using Real-World Evidence
Authors: Sun Ran , Banerjee Imon , Sang Shengtian , Joseph Jennifer , Schneider Jennifer , Hernandez-Boussard Tina
Published: February 2021

Key
Points

·
About one-third of patients with type 1
diabetes were found to use continuous glucose monitoring (CGM) and/or
continuous subcutaneous insulin infusion (CSII) in routine clinical care.

·
Disparities exist in CGM and CSII adoption,
with device use more common in patients of higher socioeconomic status.

·
Mining clinical narratives with natural
language processing techniques can be applied successfully for medical device
surveillance and cohort identification for observational studies.

·
CGM use in conjunction with CSII after type 1
diabetes diagnosis is more effective than other therapy regimens and may
translate to improved long-term glycemic control.
The use of NiAl Coating Deposited by ESD Against the Wear of Sliding Wire in GMAW Contact Tips
Authors: YAZAR Mustafa , KUL Milat , ALP Ali Kemal , TALAŞ Şükrü
Published: February 2021

The wear during the sliding of wire in GMA welds causes the contact tips to be replaced after a certain number of hours of service. In order to reduce the wear, GMAW weld contact tips were coated by NiAl using ESD (Electro Spark Deposition) with 60V and 500 Hz under Argon. The testing of contact tips were done on robotic GMAW stations and standard metallographic techniques and SEM microscopy were used to reveal the microstructure. The results indicate that the service life of contact tips can be extended as much as 50 % compared to uncoated contact tips in concern via the use of W and NiAl coating, affecting the wire friction wear performance during high temperature welding process
FLORONYM МАК / POPPY IN THE NATIONAL WORLD CONCEPTION OF UKRAINIAN AND ENGLISH SPEAKERS
Authors: Cherniavska Antonina
Published: February 2021

The article is an attempt to study the semantics of floronyms мак / poppy in the Ukrainian and English languages. It focuses on the study of the inner form of idioms and paroemias that have the analysed component-flower as a part of their structure. Universal characteristics of the semantics of the given floronyms have been researched. Specific national features of the semantics of the analysed floronyms are singled out for both languages under research. The concepts that are phraseologically actualized in the Ukrainian and English languages due to the semantic components of floronyms мак / poppy have been deduced. Metaphoric meanings of the floronyms under analysis that serve as constituents in idiomatic units and paroemias of the contrasted languages have been scrutinized. Cultural significance of the flowers poppy / мак has been revealed for both linguocultures. Symbolical meanings of the analysed floronyms have been examined in the Ukrainian and English linguocultures.
CONTINUOUS CASE STUDY AS AN EFFECTIVE METHOD OF ENGLISH LANGUAGE LEARNING BY FUTURE ENGINEERS
Authors: Halatsyn Kateryna , Feshchuk Alla , Galaidin Andrii
Published: February 2021

The present paper addresses the issue of teaching foreign language as an indispensable course at university. One of the demands to the training of future engineers is to prepare them for solving professional tasks and situations. A continuous case study method is one of the forms of problem-based learning which allows teachers to model fragments of future professional activity, its multicultural context. We suggest a continuous case study method as a powerful tool for modelling real professional activities, which contributes to the formation of professionally oriented English-language competence of future engineers. In our article, we aim to reveal the essence and stages of using the method of continuous case studies at English classes. We outlined the following methods: analysis, synthesis, generalization, systematization, inference, observation. In order to verify our statement, we conducted a continuous case study on the topic “Refutation of inaccurate information on technical operation and repair of lifting mechanisms at the enterprise”. As shown by the results of our research, a continuous case study method is a way of development of a professionally oriented English-language competence of the future engineers by involving them in solving imaginary professionally oriented problems through simulated engineering environment. It has been found that the use of a continuous case study method in the course “Practical Course of Foreign Language for Professional (Scientific) Purposes” contributes to the improvement of the future engineers’ professionally oriented foreign-language competencies in listening, speaking, reading; professionally oriented sociocultural, linguistic, educational, strategic and pragmatic competencies.
Formación del profesorado ecuatoriano en autismo y asperger
Authors: Narváez Intriago Johana Lourdes , Lara Lara Fernando
Published: February 2021

El presente trabajo pretende relatar la experiencia de formación que supuso la implementación de un módulo de sensibilización para la atención de estudiantes con trastorno generalizado del desarrollo (autismo y asperger) dirigido al profesorado de educación básica media y elemental de una institución educativa en Santo Domingo (Ecuador). En el módulo se plantearon los siguientes temas principales: conceptualización, diagnóstico, características y estrategias para atender a estudiantes diagnosticados con autismo y asperger. La investigación fue de corte cualitativo, aunque también se utilizaron técnicas cuantitativas para el análisis de datos, mientras que el diseño fue no experimental. Se aplicaron encuestas a 15 docentes de la educación básica media y elemental en dos momentos (pretest y postest) para conocer el impacto del referido módulo, denominado Atendiendo a la diversidad sin exclusión, el cual procuró fomentar una cultura inclusiva en la institución desde el reconocimiento de ese trastorno. Entre los resultados principales se pueden mencionar la necesidad de formación docente actualizada sobre estrategias y metodologías de atención a estos estudiantes, así como la ausencia de una cultura inclusiva que reconozca los valores que aportan a la sociedad como consecuencia de una aparente cultura escolar asistencial. En cuanto a las conclusiones, se puede decir que en los participantes se reflejaron dificultades referidas a la identificación y diferenciación de los distintos trastornos, así como sobre el reconocimiento de las aportaciones que estas personas pueden realizar a la sociedad y a su grupo de iguales. En síntesis, se evidencia una predominante visión asistencial etnocéntrica e incompatible con una cultura educativa inclusiva.
Examining the municipal-level representativeness of the Canadian Longitudinal Study on Aging (CLSA) cohort: an analysis using Calgary participant baseline data
Authors: Norberg Samantha J. , Toohey Ann M. , Jones Sian , McDonough Raynell , Hogan David B.
Published: February 2021

Introduction

The Canadian Longitudinal Study on Aging (CLSA) is a rich, nationally representative population-based resource that can be used for multiple purposes. Although municipalities may wish to use CLSA data to address local policy needs, how well localized CLSA cohorts reflect municipal populations is unknown. Because Calgary, Alberta, is home to one of 11 CLSA data collection sites, our objective was to explore how well the Calgary CLSA sample represented the general Calgary population on select sociodemographic variables.

Methods

Baseline characteristics (i.e. sex, marital status, ethnicity, education, retirement status, income, immigration, internal migration) of CLSA participants who visited the Calgary data collection site between 2011 and 2015 were compared to analogous profiles derived from the 2011 National Household Survey (NHS) and 2016 Census datasets, which spanned the years when data were collected on the CLSA participants.

Results

Calgary CLSA participants were representative of the Calgary population for age, sex and Indigenous identity. Discrepancies of over 5% with the NHS and/or 2016 Census were found for marital status, measures of ethnic diversity (i.e. immigrant status, place of birth, non-official language spoken at home), internal migration, income, retirement status and education.

Conclusion

Voluntary studies face challenges in recruiting fully representative cohorts. Communities opting to use CLSA data at a municipal level, including the 10 other CLSA data collection sites, should exercise caution when interpreting the results of these analyses, as CLSA participants may not be fully representative of the local population on select characteristics of interest.
Effets de la suppression des mesures incitatives s’ajoutant à la rémunération à l’acte sur les services spécialisés liés aux maladies chroniques : une analyse des séries chronologiques
Authors: Appleton Andrew , Lam Melody , Le Britney , Shariff Salimah , Gershon Andrea
Published: February 2021

Introduction

On sait que les modèles de rémunération des médecins ont des répercussions sur la nature et le volume des services offerts. Notre objectif était d’étudier les effets de la suppression d’un incitatif financier, la prime à la rémunération à l’acte, sur la prestation de services de suivi des maladies chroniques par des spécialistes en médecine interne, en cardiologie, en néphrologie et en gastroentérologie.

Méthodologie

Nous avons recueilli des données administratives liées aux soins de santé pour la période du 1er avril 2013 au 31 mars 2017 à partir des bases de données de l’Institute for Clinical Evaluative Sciences (ICES) en Ontario (Canada). Nous avons effectué une analyse des séries chronologiques avant et après le retrait de la prime à la rémunération à l’acte, le 1er avril 2015. La variable principale de résultat était le nombre total de visites mensuelles pour des services de suivi des maladies chroniques. Les variables secondaires de résultat étaient les visites mensuelles pour l’ensemble des services de suivi ainsi que les consultations de nouveaux patients. Nous avons comparé des spécialistes en médecine interne, en cardiologie, en néphrologie et en gastroentérologie exerçant pendant la période visée par l’étude avec des spécialistes en pneumologie, en hématologie, en endocrinologie, en rhumatologie et en maladies infectieuses, qui pouvaient quant à eux continuer à percevoir la prime. Nous avons choisi ce groupe de comparaison car ce sont également des sous-spécialités en médecine interne et elles offrent des services similaires.

Résultats

Le nombre de visites consacrées au suivi des maladies chroniques a diminué de façon importante après le retrait de la prime à la rémunération à l’acte, mais il n’y a pas eu de diminution du nombre total de visites de suivi. Une baisse importante des consultations avec de nouveaux patients a également été constatée. Aucun changement n’a été observé dans le groupe de référence.

Conclusion

La diminution du volume des visites de suivi des maladies chroniques peut s’expliquer par le fait que les critères de diagnostic ont été moins souvent remplis plutôt que par une réduction réelle des services fournis. Les effets potentiels sur les résultats pour les patients exigent d’être examinés de manière plus approfondie.
Hercules in the Colombian Constitutional Court
Authors: Vallejo Iván Garzón , González Cristian Rojas
Published: February 2021

This paper explores how the Colombian Constitutional Court has used the legal and political philosophy of Ronald Dworkin to show that the use of the concepts of rights as trump cards, individual autonomy, and state neutrality, have configured the reception of egalitarian liberalism. This conclusion is reached by means of an analysis of the meaning and use of these concepts in certain judicial decisions and of personal interviews with certain head justices and law clerks of said Court, which also made it possible to frame this question within the larger issue of the relationship of philosophy to the decisions of the judges.
Jarak Pisah Sudut Puncak Difraksi Antara Bidang (hkl) Utama Sebagai Indikator Keorthorhombikan Struktur Kisi Kristal Fase GdBa2Cu3O7-?
Authors: Permana I Komang Wahyu Surya , Sumadiyasa Made , Windarjoto Windarjoto
Published: February 2021

Keothorhombikan suatu struktur kisi kristal ditunjukkan oleh adanya perbedaan nilai parameter kisi a, b dan c. Penelitian ini bertujuan untuk menunjukkan bahwa nilai jarak pisah antara sudut puncak difraksi kedua bidang (hkl) yang paling dekat sama dengan nilai orthorhombisitas struktur kristal pada fase GdBa2Cu3O7-?. Untuk tujuan  tersebut, dalam penelitian ini telah disintesis senyawa Gd0,85La0,15Ba2-xSrxCu3O7-dengan variasi x = 0,00, 0,05, 0,10, 0,20, 0,30 dan 0,50. Sampel disintesis menggunakan metode reaksi padatan  dengan pencampuran basah, disintering pada suhu 900°C selama 12 jam. Dari hasil analisis spektrum XRD dengan software Match-3 dan Rietica didapatkan bahwa, dengan bertambahnya kandungan Sr pola perubahan nilai jarak pisah sudut puncak difraksi bidang (hkl) terdekat hasil pengukuran dan  perhitungan sama dengan pola perubahan nilai keorthorhombikan. Hasil pengukuran  dan  perhitungan nilai jarak pisah antara sudut puncak difraksi untuk bidang (020) dan (200) hampir sama dengan sepersepuluh dari nilai keorthorhombikan. Dengan demikian, nilai jarak pisah antara sudut puncak difraksi dari dua bidang (hkl) terdekat dapat digunakan sebagai indikator keorthorhombikan struktur kristal fase GdBa2Cu3O7-?.
Identifikasi Deformasi Pulau Bali Berdasarkan Rekaman Data GPS, Menggunakan Software GAMIT/GLOBK 10.6
Authors: Suarbawa Komang Ngurah , Sukarasa I Ketut , Riyono Elvin
Published: February 2021

Telah dilakukan penelitian aktivitas tektonik Pulau Bali yang bertujuan untuk mengidentifikasi dan menentukan arah pergerakan deformasi pulau Bali. Penelitian dilakukan dengan menggunakan data hasil pencatatan GPS lokal di sebelas titik pengamatan di Pulau Bali. Pengolahan data dilakukan menggunakan SOFTWARE GAMIT/GLOBK 10.6 dan beberapa software pendukung seperti teqc untuk menguji kualitas data perekaman GPS dan GMT untuk memplot data hasil pengolahan. Hasil penelitian menunjukkan bahwa terjadi pergeseran titik pengamatan yang mengindikasikan adanya aktivitas tektonik di Pulau Bali. Pola pergeseran titik menunjukkan terjadinya pergeseran yang cenderung ke arah timur hingga tenggara. Pola deformasi tersebut diperkirakan terjadi akibat aktivitas lempeng tektonik yang berada di bagian timur dan selatan pulau Bali.
Tri Hita Karana Memoderasi Partisipasi Penyusunan Anggaran, Asimetri Informasi, dan Komitmen Organisasi terhadap Sennjangan Anggaran
Authors: Diviariesty Kadek , Asri Dwija Putri IGAM
Published: February 2021

This study aims to determine the effect of budgetary participation, information asymmetry and organizational commitment to budgetary slack with the Tri Hita Karana culture as a moderating variable. The analysis technique used is Moderated Regression Analysis. The results showed that budgetary participation and organizational commitment had no significant effect on budgetary slack. Information asymmetry has a positive effect on budgetary slack. The interaction between budgeting participation and the Tri Hita Karana culture is unable to moderate budgetary participation against budgetary slack. The interaction of information asymmetry with the Tri Hita Karana culture is able to weaken the positive influence of information asymmetry on budgetary slack. The interaction between organizational commitment and the Tri Hita Karana culture is unable to moderate organizational commitment to budgetary slack.

Keywords: Tri Hita Karana; Budgetary Participation; Information Asymmetry; Organizational Commitment; Budgetary Slack.
Implementasi e-FAKTUR 2.2 dan PMK 62/PMK03/2015 atas Pupuk Bersubsidi Perspektif Distributor
Authors: Midiawati Endang Sri , Herwanti Titiek , Husnan Lalu Hamdani
Published: February 2021

E-fakur 2.2 is a manifestation of  Undang-undang No. 42 of 2009 concerning Value Added Tax (VAT) which does not accommodate VAT subsidies for commodity Fertilizer packages which have an impact on SAS VAT for distributors. This study aims to see how the implementation of subsidized fertilizer commodity e-invoices with the government-borne method (PPN DTP). General problems regarding the legal basis which technically only explain down to the producer level. The results of observations in a case study by processing data from 2016 onwards show problems in their implementation, both from administration, validation sistems and developing information on supervision and cross-information, especially on the management of SAS PPN through e-faktur2.2 from the distrbutor perspective.

Keywords : E-Faktur; VAT Subsidized; Subsidized Fertilzer.
Faktor-Faktor yang Memengaruhi Pemilihan Karir sebagai Konsultan Pajak
Authors: Arini I Gusti Ayu Agustia , Noviari Naniek
Published: February 2021

This study aims to determine whether professional training, professional recognition, work environment, gender roles, and the influence of parents influence career choices as tax consultants. The theory used in this research is Theory of Planned Behavior (TPB). The population in this study were employees of the LMATS Consulting tax consultant and the total sample was 60 employees using the questionnaire method data collection technique with purposive sampling, namely employees of the accounting division or tax division, who have worked at least 1 year with the latest education of D3. Research location at the LMATS Consulting Tax Consultant office. The results of this study indicate that professional training, professional recognition, work environment, gender roles, and the influence of parents have a positive effect on career choices as a tax consultant in the LMATS Consulting tax consultant office.

Keywords: Career; Tax Consultant; Employee.
Analisis Kontribusi Pendapatan Sektor Pariwisata terhadap Pendapatan Asli Daerah Kabupaten Gianyar
Authors: Mardiana Gusti Ayu Herlin
Published: February 2021

This study analyzes three variables, namely Gianyar Regency PAD, PHR and retribution for recreation and sports. The analytical tool used in this study is contribution analysis, linear regression. This study uses secondary data, so that the data collection method used is the method of non-participant observation. Based on the results of the analysis, it is known that the contribution of tourism sector revenues from PHR and retribution for recreation and sports reached an average of 44.71 percent during 2002-2017. The results of this study can be a reference for the Gianyar Regency Government that revenue from the tourism sector has a large contribution to the Gianyar Regency PAD, so the Gianyar Regency Government is increasingly motivated to continue to improve facilities and infrastructure in the tourism sector that can support increased income from the tourism sector.

Keywords: Hotel And Restaurant Tax; Retribution For Recreation And Sports; Local Revenue.
التكاليف الاقتصادية للحوادث المرورية في محافظة السليمانية وتأثيرها في الناتج المحلي الإجمالي للمدة (2030 - 2003) - دراسة تحليلية قياسية-
Authors: AHMED YOUNIS ALI
Published: February 2021

إن ظاهرة الحوادث المرورية تمثل إحدى الظواهر والمشاكل الاقتصادية، الاجتماعية والأمنية المعاصرة والتي تحمل أبعاد محلية،إقليمية ودولية وفي الوقت نفسه، فإن هنالك جهات ومؤسسات معنية كثيرة ومتنوعة لها ارتباط مباشر وغير المباشر بهذا الظاهرة المتسارعة النمو .وعلي الرغم من المحاولات والجهود المتواصلة لتقليل هذه الظاهرة و تخفيف أثارها السلبية الاقتصادية، الاجتماعية والبشرية، إلا أنه لاتزال هذه الظاهرة في الاتساع وتصل إلى مرحلة الإنذار خصوصا في محافظة السليمانية - إقليم كوردستان العراق وقد تصل إلى حد الخطر على الموارد البشرية و لاقتصاد الإقليم، ويهدف هذا البحث إلى تسليط الضوء على التحليل الاقتصادي القياسي لتكاليف الاقتصادية للحوادث المرورية في محافظة السليمانية وتأثيرها في الناتج المحلي الإجمالي في إقليم كوردستان للمدة (2019 - 2003) باستخدام (Stepwise Least Squares و Generalized Linear Model) وبتطبيق بعض المؤشرات والنماذج القياسية المتقدمة(ARMA Maximum Likelihood) وللتنبؤ بمسار هذه الظاهرة للمدة (2020 - 2030). وقد توصل البحث إلى عدة أستنتاجات من خلال تحليل البيانات المعتمدة في هذا البحث حيث وجدت أن التكاليف الاقتصادية للحوادث المرورية في محافظة السليمانية ازدادت سنة بعد أخرى، وانعكس ذلك بشكل سلبي و واضح على الناتج المحلي الإجمالي في إقليم كوردستان، ففي سنة 2003 كانت التكاليف الاقتصادية في محافظة السليمانية كانت (8949 ألف دولار)، وأصبحت هذه الخسائر (10080 ألف دولار) في سنة 2019 أي بزيادة قدرها (12.64%) حيث بلغ المجموع الكلي لهذه التكاليف (142 مليون دولار) خلال مدة (2003 – 2019)، وعليه فإنه إذا زاد التكاليف الاقتصادية بمقدار (1%)فإن ذلك يؤدي إلى انخفاض الناتج المحلي الإجمالي في إقليم كوردستان بمقدار (2.32 %). ومن المتوقع أن يزداد هذا التأثير السلبي للحوادث المرورية في السنوات العشرة القادمة وسوف يؤدي إلى انخفاض الناتج المحلي الإجمالي بمقدار (9.82%) . وبناء على ذلك فإنه نجد من الضروري الاهتمام المتزايد بتثقيف قائدي المركبات بأنواعها ورفع درجة الوعي المروري خلال المناهج التربوية و التعليمية أو من خلال القنوات الإعلامية المختلفة ، وكذلك ضرورة تغيير الأهداف والسياسات لحكومة الإقليم وتحديد الجهات المعنية للاهتمام أكثر بتأهيل البنية التحتية من خلال تخصيص ميزانية كافية لتطوير النقل العام وإنشاء الأنفاق والجسور و كذلك الحد من الاستيراد العشوائي للسيارات و كذلك مراعاة الظروف المحلية في استيراد السيارات والتي هي من الأسباب الرئيسة للحوادث المرورية وتغيير أهداف وطرق وأساليب المراقبة على السيارات بدلا من التركيز على الإيرادات بغية منع الخسائر المادية والبشرية الكبيرة .
English lexical enrichment: methods and their frequency/productivity in 1785, 1885, and 1985
Authors: Omar Rozgar Y , Jawzal Nechirvan Hassan
Published: February 2021

There are a number of different categories of enriching English vocabulary, and they are grouped into smaller methods based on the way they function. Some methods are productive while some others are creative. Besides, some methods are more or less frequent/productive than others which may be due to a number of reasons such as the nature of the language itself and possibly the period the language is undergone on. Therefore, three different years from different centuries, precisely 1785, 1885, and 1985, are taken from Oxford English Dictionary (OED) to discover the frequency/productivity of the methods in each. The concrete results show that the language and time play the role in the frequency and productivity of each method. They also indicate that the frequency of some methods has gradually increased while of some others decreased.

Keywords: lexical enrichment, word-formation, frequency, productivity, OED.

پوختە:

ژمارەیەک پۆلین هەن بۆ دەوڵەمەندکردنی ووشەی ئینگلیزی و کراونەتە چەند رێگەیە (میتۆد)کی بچووکتر لەسەر ئەو بنەمایەی کاردەکەن. لەکاتێکدا هەندێ لە رێگەکان بەرهەمهێنەرن بەڵام هەندێکی تر دروستکەرن. هەروەها، وە هەندێک لە رێگاکان کەمتر بەکاربەرن/ بەرهەمهێنەر لە هەندێکی تر، کە دەشێ لەبەر چەند هۆکارێک بن وەکو سروشتی خودی زمانەکە و ئەو ماوەیەی زمانەکە پێیدا تێپەڕیووە. بۆیە، سێ ساڵی جیاواز لە سێ سەدەی جیاواز، ١٧٨٥ و ١٨٨٥ و ١٩٨٥، هەڵبژێردراون لە 'فەرهەنگی ئینگلیزی ئۆکسفۆرد (OED)' بۆ لێکۆڵینەوە و دۆزینەوەی رێژەی بەکاربردن/بەرهەمهێنی میتۆدەکان. ئەنجامەکان دەریدەخەن کە زمان و کات رۆڵێکی کاریگەر دەگێڕن لە بەکاربردن و بەرهەمهێنی هەر میتۆدێک. وە ئەنجامەکان ئەوەش دەردەخەن کە بەکاربەری هەندێ میتۆد زیادیکردووە و لەکاتێک هەندێک کەمیکردووە.

ووشە گرنگەکان: دەوڵەمەندکردنی ووشەیی، ووشەسازی، بەکاربردن، بەرهەمهێنی، '(OED)'.

الملخص:

هناك عدد من الفئات المختلفة لتعزيز و لتكوين مفردات اللغة الإنجليزية ، ويتم تجميعها في طرق أصغر بناءً علی وظيفتهم في تكوين المفردات. بعض الطرق منتجة والبعض الآخر تكون مبدعة. من ناحية اخرى، تكون بعض الأساليب أكثر أو أقل تكرارًا/ إنتاجية من غيرها والتي قد تكون ناتجة عن عدد من الأسباب مثل طبيعة اللغة نفسها وربما الفترة التي تمر بها اللغة. لذلك ، تم أخذ ثلاث سنوات مختلفة من قرون مختلفة ، بالتحديد 1785 و 1885 و 1985 ، من قاموس أكسفورد الإنجليزي (OED) لاكتشاف تكرار / إنتاجية الطرق في كل منها. تظهر النتائج البحث بأن اللغة والوقت يلعبان دورًا في تكرار وإنتاجية كل طريقة. كما تشير إلى أن تواتر بعض الأساليب قد ازداد تدريجيًا بينما انخفض البعض الآخر.

الكلمات المفتاحية: الإثراء المعجمي ، تكوين الكلمات ، التردد ، الإنتاجية ، OED.
Estrategia contra la extracción ilícita de yacimientos mineros 2020-2030
Authors: Camargo Calderón Fabricio
Published: February 2021

En el desarrollo del conflicto armado colombiano, se han generado innumerables dinámicas de economías ilícitas; no obstante, este aspecto tiene como relevancia especial el incremento de las actividades que se han presentado sobre la extracción ilícita de yacimientos mineros. Lo anterior ha facilitado, por causa de diversos factores como, la mutación y la capacidad de adaptación de las organizaciones delincuenciales, el afianzamiento de las condiciones para su crecimiento y la ausencia del control institucional o su débil presencia en las regiones del territorio. Ocasionando de esta manera, el incremento de espacios vacíos de autoridad y esto a su vez, favorece la marginalidad social, política y económica que se refleja en la falta de satisfacción de las necesidades básicas, siendo este un escenario de gran provecho para las estructuras delictivas. En contraste, y junto al impacto ambiental e irreversible que la extracción ilícita de yacimientos mineros ocasiona en el agua, la biodiversidad y el medioambiente (contemplados como activos estratégicos de la nación por la “Política de Defensa y Seguridad” 2019-2022), se debe buscar la forma más efectiva de contrarrestar esta práctica destructiva, para así defender y proteger de acuerdo con el mandato constitucional los recursos vitales para la supervivencia de la nación y que adicionalmente hacen parte de los intereses nacionales y prevalentes; por lo que son prioridad para la seguridad nacional. Precisamente, lo anterior permite la generación de mecanismos que facilitan la articulación del esfuerzo de la acción unificada del Estado, como herramienta principal para lograr la disrupción de este delito, que afecta de manera significativa los ecosistemas, las comunidades y la economía en el territorio nacional. De ahí, la importancia que representa fortalecer la estrategia actual contra esta actividad ilícita, empleando toda la capacidad institucional en lo social, jurídico, ambiental, económico y militar, con el propósito de establecer dinámicas determinantes dentro del proceso de transformación de criminalidad y legalidad, y, asimismo, alcanzar mejores prácticas en las etapas de exploración, desarrollo de la actividad minera y explotación económica, que desencadenan los fenómenos de afectación institucional y que no permiten cumplir con las expectativas de la población en lo concerniente a las oportunidades de desarrollo sostenible con equidad.
Aspectos cognitivos da pessoa idosa na aposentadoria: uma revisão sistemática
Authors: Farias Neméia de Oliveira , Fujita Luana Suemi , Silva Cinthia Fernanda da Fonseca , Gasparotto Guilherme da Silva , De Oliveira Valdomiro , Vagetti Gislaine Cristina
Published: February 2021

Objetivo: Revisar sistematicamente evidências dos aspectos cognitivos da pessoa idosa relacionados à aposentadoria. Métodos: A busca foi realizada em dez bases de dados: Bireme (BVS), Ebsco, Eric, Oxfford Journals, Scielo, Lilacs, PsycINFO, Scopus, ScienceDirect e Web of Science. Foram selecionados artigos de observação relacionados à cognição e à aposentadoria de pessoas com 60 anos ou mais, publicados no período de janeiro de 2010 a abril de 2020. A qualidade dos artigos foi verificada por dois revisores independentes por meio do Strengthening the Reporting of Observational Studies in Epidemiology – STROBE. Resultados: Sete estudos preencheram os critérios de inclusão, dentre os quais, quatro artigos abordaram a cognição relacionada à complexidade do trabalho; um artigo analisou a cognição a partir da relação entre trabalhadores pagos, aposentados e donas de casa; um artigo analisou a cognição de aposentados empregados e não empregados; e um artigo analisou o desempenho cognitivo em idosos observando a maneira como estes consideraram o trabalho que exerciam e sua adaptação a vida pós-aposentadoria. Considerações finais: As características do emprego são preditores importantes para a saúde mental dos trabalhadores antes e após a aposentadoria, especialmente quando se relaciona o desempenho cognitivo com a maior complexidade do trabalho com dados.