bluuebunny/crossref_metadata_2025 huggingface dataset:
Efectos de la deficiencia de hierro en el funcionamiento intelectual
Authors: Pollitt Ernesto
Published: September 2020

El propósito de este trabajo es el de presentar un análisis comparativo de los resultados de seis investigaciones en las cuales ha participado el autor sobre la relación entre la deficiencia de hierro y el funcionamiento intelectual. Las investigaciones fueron realizadas en Egipto, Estados Unidos, Guatemala, Indonesia y Tailandia entre niños de edad pre-escolar. La deficiencia de hierro con anemia está entre las dos deficiencias nutricionales más prevalentes en el mundo y es de esperar que su prevalencia sea alta en el Perú, particularmente entre los infantes y niños y entre las madres gestantes y lactantes. Una de las causas importantes es el limitado consumo de alimentos ricos en hierro hemínico que generalmente son muy costosos para los grupos más pobres de la sociedad. El análisis comparativo muestra que los resultados son consistentes a través de los seis estudios y que la deficiencia de hierro con anemia afecta el rendimiento en las pruebas de procesos cognoscitivos específicos y en las pruebas de rendimiento escolar. Los resultados también muestran que dichos efectos son reversibles con el tratamiento apropiado. A su vez, el análisis muestra que no hay evidencia suficiente para inferir que la deficiencia de hierro sin anemia afecta el cociente intelectual.   The purpose of this paper is to present a comparative analysis of the results of six researches in which the author has participated, about the relation between iron deficiency and intellectual performance. The researches were carried out in Egypt, U.S.A., Guatemala, Indonesia and Thailand, with pre-school and school children. Iron deficiency with anemia are among the two nutritional deficiencies of major prevalence in the word and it must be expected that the same goes for Peru. One of the causes of the low consuming of food rich in iron is that these are too expensive for groups of low socioeconomic level. The comparative analysis shows consistent results in the six studies and that iron deficiency affects achievement in cognitive processes tests and academic tests. Results also show that the effects are reversible when appropriate treatment is given. At the same time, the analysis shows that there is not enough evidence to infer that iron deficiency without anemia affects the intellectual quotient.
Acerca de la institucionalización de la psicología como profesión en el Perú y de un aspecto de su devenir como disciplina científica
Authors: Lerner Stein Roberto
Published: September 2020

El presente artículo intenta reseñar los principales hechos que antecedieron a la creación del Colegio de Psicólogos del Perú en 1980, analizando las condiciones de representatividad académica y profesional que existían en la Sociedad Peruana de Psicología. Igualmente, plantea algunas explicaciones y aclaraciones respecto de las dicotomías intuitivo-objetivo y oral-escrito a propósito de un trabajo presentado en este mismo número por Federico León.
Tratamiento psicológico, según la terapia racional emotiva
Authors: Amorós Víctor
Published: September 2020

En este artículo el autor presenta el caso de un paciente de 30 años, de sexo masculino, soltero, quien sufre de ansiedad, depresión e incapacidad para enfrentar el trabajo. Se describen los datos más importantes de la historia y el motivo de consulta y se relatan algunas sesiones de terapia racional emotiva.
El movimiento humano en las láminas proyectivas: una aportación a la III del test de Rorschach
Authors: Jiménez Gomez Fernando , Diego Vallejo Raúl De , Sánchez Crespo Guadalupe
Published: September 2020

El presente artículo pretende analizar las interpretaciones de Movimiento Humano (M) que se perciben en la Lámina m del test de Rorschach y en las "Láminas Proyectivas". En este sentido las Láminas Proyectivas del Dr. Rodríguez Isidoro constituyen una de las medidas más efectivas para discriminar y analizar la actividad mental expresada con las interpretaciones de movimiento cuando éste aparece en la Lámina m de Rorschach. Los autores han elaborado un diseño con una muestra de 300 sujetos aleatoriamente elegidos. Se llevó a cabo un estudio con dos grupos de sujetos, 150 adolescentes y 150 adultos, sin evidencia de características patológicas. Se han obtenido las diferentes medidas del movimiento humano en las láminas de Rorschach y en las Proyectivas. Comparando los resultados muestran algunas diferencias significativas en los contenidos humanos con movimiento. Se encontraron sistemáticamente diferencias en las respuestas "M" tanto en Rorschach contó en las Láminas Proyectivas 1 y 11.
Análisis discriminativo de la personalidad antisocial mediante la técnica elección de W. Morgenthaler
Authors: Diego Vallejo Raúl De , Jiménez Gómez Fernando
Published: September 2020

En este artículo los autores han realizado un análisis de la personalidad antisocial (30 l. 70: DSMm- R) a través de t Rorschach. En concreto han utilizado la técnica de Morgenthaler aplicada a 105 delincuentes y 111 soldados (grupo control). Los resultados han revelado la existencia de importantes diferencias entre ambos grupos. Las láminas VIll y X han sido las más aceptadas entre los soldados. Por su parte, los delincuentes prefieren mayormente las láminas VII y IV. Las diferencias entre las láminas preferidas y las rechazadas no fueron estadísticamente significativas.
Adaptación del inventario de estilos de aprendizaje de Kolb
Authors: Escurra Mayaute Luis Miguel
Published: September 2020

El propósito de este trabajo es el de presentar el estudio de adaptación del Inventario de estilos deaprendizaje (lEA). Se trabajó con 250 estudiantes Universitarios de ambos sexos pertenecientes a la especialidad de Psicología de U.N.M. de San Marcos y la P. U. Católica del Perú. El inventario fue sometido a un estudio piloto que demostró la necesidad de cambiar el formato de aplicación. El análisis psicométrico incluyó el estudio de la Validez de Contenido y la Validez de Construcción por medio del método interpruebas. Los resultados obtenido permiten concluir que el inventario de estilos de aprendizaje en su versión Lima tiene validez y confiabilidad
Percepción de los adolescentes de clase socioeconómica media, baja, urbana y baja marginal de Lima respecto a las prácticas de crianza de sus madres res sus
Authors: Majluf Alegría , Quesada Rosario
Published: September 2020

Basándose en un estudio realizado por Majluf en 1989, se llevó a cabo un estudio exploratorio para comprobar el grado de concordancia en la percepción que los hijos adolescentes tienen de las prácticas de crianza de sus madres y las utilizadas por ellas.Se aplicó la prueba de "Prácticas de Crianza" de Block a 160 adolescentes de clase socio económica media, baja-urbana y baja marginal ( 40 en cada CSE) provenientes de colegios estatales y particulares de Lima. Los resultados mostraron diferencias entre los adolescentes de CSE M y CSE S-urbana y aquellos que provienen de CSE S-marginal con relación al patrón democrático. No se observaron diferencias en los tres grupos en cuanto al afecto que sus madres les brindan. Se hallaron diferencias significativas con relación al patrón autoritario. Los adolescentes de CSE S-urbana perciben a sus madres como menos autoritarias que los adolescentes de CSE M y menosaún que los de CSE S-marginal. Se discuten ciertas inconsistencias en los resultados.
El enfoque sistémico en terapia familiar
Authors: Zevallos Vega Roxana
Published: September 2020

La autora resalta algunos aspéctos de la aparición de la Terapia Familiar y describe las etapas por las que ha evolucionado, destacando el rol de autores como Hoffman, Minuchin, Maturana, entre otros. Se indica los inicios de la Terapia Familiar en el Perú, mencionándose la creación de grupos de profesionales que trabajan en este campo.
Editorial. El etnocidio del otro también es nuestra propia muerte.
Authors: Mojica Mendieta Francisco Javier
Published: September 2020

Este editorial plantea el problema del etnocidio del Otro como el modusoperandi equivalente al asesinato-suicidio contra la humanidad misma. Para Este editorial plantea el problema del etnocidio del Otro como el modus operandi equivalente al asesinato-suicidio contra la humanidad misma. Para ello, se problematiza los asesinatos en Costa Rica de Yeri Rivera Rivera, líder indígena Bröran de Térraba, el pasado 24 de febrero de 2020 y; de Sergio Rojas Ortiz, líder indígena Bribri, cometido el 18 de marzo de 2019, en el proceso de la recuperación de sus territorios frente a usurpadores no indígenas y sus aliados. Metodológicamente, se realizó un acercamiento etnográfico con entrevistas abiertas para lograr un acercamiento dialógico con sus compañeros de lucha. Lo analizado permite concluir que ambos asesinatos tienen una profunda raíz de racismo en Costa Rica y otros países del Sur Global; tiene como blanco la desaparición forzada de líderes y lideresas indígenas y activistas sociales; forman parte del colonialismo interno; se comete con ello el etnocidio del Otro, que es también nuestra propia muerte y; como otros tantos asesinatos, siguen impunes. Como parte de nuestro compromiso desde la universidad pública, Trama, la Revista de Ciencias Sociales y Humanidades ante a estos hechos, se posiciona como un espacio para la comunicación de conocimiento liberador del racismo, la xenofobia, el patriarcado, el capitalismo y el colonialismo.
Palabras clave: colonialidad, emancipación; humanismo; lucha social.
COVID-19 e Pneumologia: Novos Desafios e Oportunidades
Authors: Clérigo Vera , Duarte Paula
Published: September 2020

N/a.
Concern with dental appearance and associated factors among the elderly of two southern Brazilian cities
Authors: Sachetti Diandra Genoveva , Pretto Zatt Fernanda , Trevizan Thais Carleso , Silva Caroline Fernandes e , Muniz Francisco Wilker Mustafa Gomes , Rösing Cassiano Kuchenbecker , Colussi Paulo Roberto Grafitti
Published: September 2020

Aim: This study aimed to evaluate the prevalence of concern with dental appearance (DA) and associated factors among the elderly of two southern Brazilian cities. Methods: A cross-sectional study was conducted in the cities of Cruz Alta and Veranópolis, Brazil. Oral health examination and a structured questionnaire were applied. Questions from the PCATool-SB Brasil tool and the Questionnaire about Teeth Appearance, both validated to Brazilian samples, were used. The collected independent variables were: sex, age, ethnicity, education level, marital status, retirement, health problem, use of medication, smoking exposure, alcohol exposure, access to the dentist, toothbrushing frequency, use of dental floss, edentulism, use of and need for dental prosthesis. Concern with DA was dichotomized into yes/no. Associations between dependent and independent variables were assessed by Chi-square or Mann-Whitney tests. Moreover, uni- and multivariate analyses were conducted by Poisson regression with robust variance. Level of significance was established as p<0.05. Results: The prevalence of concern with DA was 18.8% (n=107). The prevalence ratio (PR) of concern with DA decreased 5.8% for each year increase (PR:0.942; 95% confidence interval [95%CI]:0.911–0.973). Elderly without access to the dentist in the last 12 months presented 62.5% (p=0.006) higher PR of concern with DA when compared to those with access to dental care. Dentate elderly showed 219% higher PR for concern with DA (PR:2.197; 95%CI:1.364–3.539) in comparison to edentulous individuals. Conclusion: Prevalence of concern with DA was low and associated with demographics, access to dental care and edentulism.
Política de internacionalização da UFES
Authors: Wassem Joyce , Ferreira Eliza Bartolozzi
Published: September 2020

Este artigo analisa de que modo a internacionalização figura nos documentos institucionais da Universidade Federal do Espírito Santo (UFES), ou seja, que conceitos, razões e estratégias são previstos na política da instituição para sua implementação. A pesquisa tem abordagem qualitativa, a coleta de dados é composta por análise documental e para o tratamento dos dados fez-se a opção pela análise de conteúdo segundo Bardin (2004). Como resultados observa-se que, criada em 1954, a UFES é considerada a principal Instituição de Educação Superior (IES) do estado do Espírito Santo (ES). Desde 2012, com a finalidade de melhoria da qualidade de seus Programas de Pós-Graduação stricto sensu (PPG), em específico, pela busca da excelência medida pelos conceitos 6 e 7, de acordo com a avaliação empreendida pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), tem elaborado e implementado um planejamento estratégico com metas e ações. Dentre as ações, está a criação de uma Secretaria de Relações Internacionais (SRI); da Rede de Internacionalização da Educação do Espírito Santo (RIEES); bem como a elaboração de um projeto conjunto, com o envolvimento de 9 PPG da instituição, no Programa Institucional de Internacionalização (PrInt) da CAPES. O que, por um lado, demonstra um esforço articulado de trabalho de seus docentes e programas e, por outro, permite observar a existência de contradições no processo de planejamento de ações para a internacionalização considerando a diversidade e especificidade dos programas e o contexto político e econômico brasileiro.
Internationalization in higher education
Authors: Wassem Joyce , Pereira Elisabete Monteiro de Aguiar , Finardi Kyria Rebeca
Published: September 2020

Although assuming new role nowadays, the internationalization of higher education is one of the integral aspects of the organization of the university in its origin. As a complex phenomenon (MOROSINI, 2006), it has demanded an explanation of its conception and planning from the Higher Education Institutions (HEI). Moreover, it demands consistent goals and strategies that meet the institutional particularities with the purpose of promoting and valuing the development of students, teachers, researchers and administrative staff. If, on the one hand, we currently see the presence of internationalization in a large number of universities, on the other, we see the need to reflect on its meaning, assumptions, policies, actions and impacts, be it in the HEI, or at the national and international level. Considering this scenario, the objective of this special issue entitled “Internationalization in higher education: assumptions, meanings and impacts”, was to provide space for analysis and dissemination of the views on internationalization that are being processed, in contemporary times, at the institutional, national and international levels. This special issue is composed of a set of nine articles and one interview, with a wide range of reflections on the topic at hand. The variety of analyses of the texts can also be observed in the diversity of institutions and regions in which the authors work both in Brazil and abroad. In this sense, the articles in this special issue represent an important contribution to the field of Higher Education and, especially, to the scholars of internationalization.
High Sensitive Troponin I and Extended Range C-Reactive Protein as Markers to Predict Cardiotoxicity in Locally Advanced Breast Cancer with Neoadjuvant CAF (Cyclophoshpamide, Adriamycin/Doxorubicin, 5Fluorouracil) Therapy
Authors: Hidayat Yusfik Helmi , Ishardyanto Hantoro , Anniwati Leonita
Published: September 2020

The limitation of echocardiography to measure chemotherapy cardiotoxicity at left locally advanced breast cancer with large ulcer is still serious problem. HsTnI and erCRP are biomarkers to detect cardiotoxicity that are cheap, easy to examine and available at Dr.Soetomo Hospital Surabaya. This study was to compare HsTnI, erCRP and echocardiography as cardiotoxicity predictors in locally advanced breast cancer with neoadjuvant CAF therapy. This study used one group pretest and posttest design among 23 locally advanced breast cancer patients. All patients underwent echocardiography, HsTnI, and erCRP examinations before and after 3 times chemotherapy and compared. The average age was 49.78±8.7. Statistically significant decrease in LVEF was found after treatment (67.98%±4.06 and 64.07%±3.53, p=0.000). HsTnI was significantly increased after treatment (0.007 µg/mL±0.004 and 0.043 µg/mL±0.051 p=0.000). erCRP was significantly decreased after treatment (1.043mg/dL±0.913 and 0.573mg/dL±0.444 p=0.044). Decreased LVEF and increased HsTnI was compared by its cardiotoxic cut-off. HsTnI was significantly better and faster to detect cardiotoxicity (0.033±0.051 p=0.002). In conclusion, strong correlation is present in the detection of cardiotoxicity between HsTnI and LVEF. HsTnI is faster than echocardiography, and could be alternative diagnostic to detect early cardiotoxicity.
The Pattern of Antibiotic Prescription and Antimicrobial Resistance of Gut Flora Escherichia coli at Aisyiyah Hospital, Bojonegoro
Authors: Hidayah Ana Nurlaili , Hasmono Didik , Thayyib Muqoddar , Kuntaman K
Published: September 2020

Antimicrobial resistance (AMR) is the failure of antibiotic to kill bacteria and becomes ineffective in therapeutic purpose. The AMR bacteria is a major health problem worldwide and Indonesia is not exception. AMR is increased by two factors, higher antibiotic use and low compliance in infection control and prevention.  WHO has recommended 7 bacterial indicators as point of view in surveillance, one of these bacteria is Escherichia coli. This study aimed to analyze the correlation between antibiotic use and resistance pattern of gut flora Escherichia coli. The study was conducted at Aisyiyah Hospital, Bojonegoro from June to October 2017. Total 101 patients from internal medicine and surgery department in this hospital were included in this study. Bacterial gut flora were tested against 12 antibiotics by disk diffusion test at the Department of Clinical Microbiology, Universitas Airlangga.. The results showed that the highest quantity of antibiotic use in internal medicine service was cefepime (40,50 DDD) and the highest resistance rate was ciprofloxacin, whereas in the surgical service it was ceftriaxone (132,75 DDD) with the highest E. coli resistance to amoxicillin-clavulanic acid. The antibiotics use has significant correlation against E. coli resistance on cefotaxime (p=0.046), ceftazidime (p=0.046), ceftriaxone (p=0.017), aztreonam (p=0.024), and cefepime (p=0.010).
Therapy Effect of Red Dragon Fruit (Hylocereus polyrhizus) Peel Extract to Increase the Number of Sertoli Cells On BALB/c Mice (Mus musculus) Exposed to Lead Acetate
Authors: Wulandari Evy , I'tishom Reny , Sudjarwo Sri Agus
Published: September 2020

Lead is the free radicals and heavy metals of major pollutants in the environment. Lead is toxic and cumulative. Red dragon fruit (Hylocereus polyrhizus) peel extract is a natural antioxidant. Red dragon fruit peel extract can be used to stabilize free radicals by supplementing electron deficiencies and inhibiting chain reactions. This study aimed to analyze therapy effect of red dragon fruit peel extract to increase the number of Sertoli cells on BALB/c mice (Mus musculus) exposed to lead acetate. Fourty mice were divided into 5 groups (each group consisted of 8 mice). K- group was the control group without lead acetate and dragon fruit peel extract administration, K + group was given 100 mg/KgBW lead acetate orally on the 1st day until day 14th.. P1, P2, and P3 group were continued with red dragon extract orally on the 15th day until 39th day. P1 with dose 250 mg/KgBW, P2 with dose 500 mg/KgBW, and P3 with dose 1000 mg/KgBW. The result showed significant difference (P<0.05) in the number of Sertoli cells between K+ and P1, P2, P3 group. In conclusion, dose 500 mg/kgBW of red dragon fruit peel extract can be used as the most effective therapy to increase the number of Sertoli cells on mice exposed to acetate lead.
The Role of Antiapoptotic Erythropoietin on Ultraviolet B-Induced Photodamaged Skin Through Inhibition of Sunburn Cells
Authors: Suyono Handi , Sanjaya Kristian , Susanti Deby
Published: September 2020

Ultraviolet light causes photodamaged skin leading to photoaging skin. Ultraviolet-B (UV-B) causes epidermal keratinocyte apoptosis, namely sunburn cell, through apoptotic intrinsic pathway. Erythropoietin (EPO) has a role in cytoprotection in various tissues but its role to epidermal skin is not clear yet. This study was designed pretest-posttest control group design. Thirty two male mice Mus musculus, strain Balbc, were divided into control and treatment group, 16 mice each group. All mice were exposured by UV-B light 16mJ/cm2, distance 30 cm, duration 90 seconds, for 3 consecutive days. Four mice each group were randomly sacrificed as pretest data. The control mice were given aquadest subcutaneous injection 0.1 mL, and treatment mice were given EPO subcutaneous injection  0.1 mL (100 IU/kg BW). UVB were given everyday with same protocol above. Treatments were given 4 times, interval 3 days. All mice were sacrificed to examine sunburn cells. Data were performed as mean ± SD and analyzed by t-test using SPSS 17.0 with significant value p<0.05. Sunburn cells of pretest control were 25.00 ± 4.85% and treatment group were 24.83 ± 5.15%. Sunburn cells significantly decreased (p=0.002) in treatment group (31.5 ± 9.39%) than control (50.83 ± 6.70%). UV-B causes sunburn cells formation. EPO inhibits apoptosis through increasing NO production and eNOS expression, inhibiting caspase and proinflammatory cytokines, and increasing antiapoptotic protein. EPO has a role in skin apoptosis inhibition which is shown by decreased sunburn cells
A Study on Knowledge Towards Brain Death among Residents in Indonesia
Authors: Fauzi Asra Al , Waloejo Christrijogo Sumartono , Machin Abdulloh , Shodiq Muhammad Ja'far
Published: September 2020

This research was conducted to evaluate the knowledge and diagnosis of brain death among resident in Indonesia. This study used an observational analytic study with a cross-sectional study design using a questionnaire. The research subjects consisted of 132 level 2 (after 2 years of residency) and level 3 (after 4 years of residency) residents, the total sampling for which was taken from the departments of Neurosurgery, Anesthesiology, and Neurology at Dr. Soetomo Academic Medical Center Hospital, Surabaya, Indonesia. Data were taken from November 2018 to January 2019. A total of 132 residents of Neurosurgery, Neurology, and Anesthesiology participated in this study. From the series of studies, residents’ knowledge of the concept of brain death was in the sufficient category (41.7%), residents’ knowledge of the technical diagnosis of brain death was in the good category (40.2%), residents’ knowledge of brain death examination was in the less category (43.2%), and finally, it was found that the resident's knowledge of brain death was in a good category (35.6%). There were also significant differences in knowledge of brain death between Neurosurgery, Neurology, and Anesthesiologist Resident (P <0.001) and knowledge of brain death between level 2 and level 3 residents (P=0.032). In general, the Indonesian resident doctors’ knowledge of brain death is adequate, but knowledge of the clinical examination of brain death is still lacking. Further research must be carried out to promote knowledge of brain death in residents as well as professional doctors/specialists, so that the number of organ transplants, especially in Indonesia, will increase.
Case Report: Cranial Vault Reduction Cranioplasty for Severe Hydrocephalus
Authors: Suryaningtyas Wihasto , Parenrengi Muhammad Arifin
Published: September 2020

Extreme hydrocephalic macrocephaly is still encountered in developing countries due to delayed treatment, rapidly progressing hydrocephalus and family socioeconomic problems. Reduction cranioplasty was used with several techniques to address the issue. The study aimed to determine the safety and feasibility of barrel-stave technique for reducing the size of extreme hydrocephalic macrocephaly. Three post-diversion patients underwent surgical reconstruction. Children with head circumference more or equal to two standard deviation above mean on given age, no active wound at the area of surgery, presentation of sufficient “potential removable fluid” that allows dura reduction and no active shunt infection were eligible. The surgical procedure includes modified pi, barrel-stave technique, and diversion of the cerebrospinal fluid and subdural collection. Clinical data were recorded. Three patients with age range of 2 month to 2 years old underwent the surgery. Two patients had shunt implanted at least 1 month before the surgery and 1 patient had an ETV procedure 3 months before the reduction. The frontal-occipital circumference before surgery ranged from 50 to 63 cm. The maximum reduction that could be achieved was 15 cm. One patient (2 months old) died within 24 hour due to failure to cope with excessive blood loss. Two patients were followed up for 3 months and 6 months without complications. Reduction cranioplasty using barrel-stave techniques is an option for children with extreme large head that poses a mechanical or cosmetic problem. Risk and pitfalls should be considered and taken care meticulously, especially the age and blood loss.
Asian Clam (Corbicula fluminea) Larvae Production in Broodstock Conditioning
Authors: Hadiana Hadiana , Eh Rak Aweng , Seong Wei Lee , Zharif M.
Published: September 2020

Nowadays, the inclining of Asian clam market demand for supplying the seller Etak in some areas in Malaysia particularly Kelantan where etak had become the main concern due to the stock availability in the natural population was over-exploited. Thus, an effort to expedite the availability seed of Etak must be initiated to conserve the Asian clam population in their habitat. Until now, the information about production larvae is needed to begin the domestication process. The scientific goal aims to evaluate the best time to produce Asian clam larvae to supply the hatchery production process. To answer this question, the evaluation of broodstock conditioning adult Corbicula fluminea monthly during a year and this condition was compared into the fine sand sediment as well as no sediment. The results showed that the Asian clam adult pattern released larvae monthly during a year wherein the great number larvae were produced 22464 Ind/L totally in December and the produced larvae in Oct and Nov was almost similar with range 22350-22500 Ind/L. The condition index with fine sand sediment was 3.8419 % higher than the control treatment 3.5750 %. And last, the ingestion rate both treatment was 1.126 ± 0.534 μg/h and control treatment 1.609± 0.434 μg/h.
The Use of Crude Fish Oil (CFO) in Vannamei Shrimp (Litopenaeus vannamei) Feed on EPA and DHA Contents
Authors: Hadi Prasetyo Januar , Agustono Agustono , Paramitha Lokapirnasari Widya
Published: September 2020

Omega-3 fatty acids (Alpha-linolenic acid) and omega-6 fatty acids (Linoleic acid) are a group of essential fatty acids. Essential fatty acids are fatty acids that cannot be synthesized by the body so that must be supplied from the diet. One of the sources of essential fatty acids is derived from fish oil. This study aims to determine the effect of Crude Fish Oil (CFO) in the feed to EPA and DHA content in penaeid shrimp meat. The research method used was a completely randomized design. The treatments used are the varying content of Crude Fish Oil (CFO), which are P0 (0%), P1 (2%), P2 (4%), P3 (6%), and P4 (8%). The results of the study showed significant differences (p <0.05) on the content of EPA and DHA in penaeid shrimp meat. The highest content of EPA and DHA found in P4 treatment (8%) and the lowest at P0 treatment (0%). The use of CFO in penaeid shrimp feed need further study related to the growth of shrimps and prawns reproductive cycle to increase the productivity of penaeid shrimp. CFO on feed should be used at a dose of 6%.
Hemoptisis pada Pasien Aspergilloma Paru Kiri
Authors: Nugroho Gilang Muhammad Setyo , Wulandari Laksmi
Published: September 2020

Background: Aspergilloma is a fungus ball (misetoma) that occurs because there is a cavity in the parenchyma due to previous lung disease. This fungus ball can move inside the cavity but does not invate the cavity wall. The presence of fungus ball causes recurrent hemoptysis. Case: We present a 45-year-old female patient with left lung Aspergilloma. Diagnosis of Aspergilloma was based on histopathology from FNAB CT guiding of left pulmonary which showed Aspergillus. Patient was treated with left superior lobe lobectomy at the hospital. The examination result of anatomical patology obtained from lung tissue was aspergillosis, from GeneXpert examination lung tissue showed positive MTB with rifampisin sensitive. Post-operative condition of the patient was stable, surgical wound improved, took off drain patient. There were clinical improvements after the surgery. Discussion: Diagnosis of Aspergilloma was based on clinical, radiology, and microbiology. Aspergilloma with severe symptoms (hemoptysis massive with life-threatening or other complications that require more than 1 time hospitalisation) and good physical condition should undergo surgical therapy in the form of lobectomy in accordance with the extent of lung abnormalities. Patient got first category anti tuberculosis drugs for 6 months and fluconazole for 2 months. Conclusion: It is necessary to consider the suspicion of Aspergillus infection, in patient with history of previous tuberculosis accompanied by a history of recurrent hemoptysis. Patient with reccurent hemoptysis and good physical condition should undergo surgical therapy.
Problem Terapeutik pada Empiema Terlokulasi karena Tuberkulosis
Authors: Marhana Isnin Anang , Anggraeni Amelia Tantri
Published: September 2020

Background: Pleural effusion is the most common complication of pulmonary tuberculosis (TB). Some coexist with secondary infection could worsen clinical presentation as empyema. The incidence of pleural effusion in the early stage of empyema due to TB infection is about 31%. Somehow, untreated empyema increased in-hospital mortality. Case: A woman with unregulated diabetes mellitus was referred with organized empyema. The etiology of empyema is based on a specific process of TB infection with the ADA value of empyema fluid was 128 mg/dl. We decided to perform decortication with the result loculated empyema and bronchopleural fistula 2 cm in the inferior lobe of the right lung. The patient did not recover well. Unfortunately, fluidopneumothorax was found on a chest CT scan with contrast. Thoracotomy was performed and another bronchopleural fistula was found which length was about 1 cm in superior lobe of the right lung. Discussion: The worsening condition of the patient was caused by the occurrence of postoperative bronchopleural fistula. It was visualized as pulmonary TB with perforation of cavity nessessity. On the other hand, the condition could be worsened by the hyperglycemic state in an immunocompromised individual. Summary: Loculated empyema is a condition caused by bronchopleural fistula, the presence of a connecting cavity between pleural and bronchus which occurred less than 48 hours. Local and systemic factors might explain the development of bronchopleural fistula. Well management of the loculated empyema by knowing the etiology could improve the life survival of the patient.
Drug Induced Hepatitis pada Tuberkulosis Paru dengan Multisite Tuberkulosis Ekstraparu
Authors: Wesnawa Made Agustya Darma Putra , Kusmiati Tutik
Published: September 2020

Background: Tuberculosis (TB) continues to be a major health problem in developing country. Lung is the most common site for Mycobacterium tuberculosis (MTB) infection, but dissemination may occur to any part of the body resulting in extrapulmonary TB. Hepatotoxicity is one of the most frequent adverse events that occur during TB treatment. Case: A 35-year-old female patient came with cough, dyspnea, fever, abdominal pain, history of mass in right inguinal lymph node, and malnutrition. Histopathology from excisional biopsy of inguinal lymph node showed granulomatous inflammation. Computed tomography of abdomen showed intraabdominal TB. Chest X-ray showed right pleural effusion, with exudate pleural fluid and mononuclear dominant. After 1 week consuming antituberculous drug, patient got nausea and vommiting, increased of ALT and AST, total and direct bilirubin. Antituberculous drug was stopped and switched to levofloxacin, ethambutol, and streptomycin. After clinical improvement and liver function return to normal, desensitization of rifampicin and isoniazide was started. Desensitization started with rifampicin for three days, and followed with isoniazide for three days. In total, the patient got rifampicin, isoniazide, and ethambutol for 9 months. Evaluation of treatments are clinical improvement and weight gain. Acid fast baccili sputum was negatif, no pleural effusion on chest X-ray, and normal abdominal ultrasound. Conclusion: MTB can spread to other organs which cause multisite extrapulmonary TB. Side effect can occur during TB treament, and this is not the reason to stop the therapy. Individual ATD therapy shows good response in this case.
Ethical clarity in clinical approaches to rabies prevention in re-exposure cases
Authors: Basu Saurav , Garg Suneela
Published: September 2020

The lack of adherence to the recommended rabies post-exposure prophylaxis guidelines by physicians during encounters with cases of animal bite re-exposure results in enormous avoidable economic costs, wastage of scarce resources, and is a significant but neglected health concern. The challenges encountered in managing animal bite re-exposure cases arise from deficiencies in the existing health system reflect an overlooked and largely unreported ethical dilemma. Healthcare providers in managing the ethical demands arising from this situation generally tend to uphold the principle of non-maleficence while overlooking the claims of distributive justice and patient autonomy.
Tunneling in Fermi Systems with Quadratic Band Crossing Points
Authors: Mandal Ipsita
Published: September 2020

We investigate the tunneling of quasiparticles through a potential barrier of finite height and width, in a system with a band structure consisting of a quadratic band crossing point (QBCP). We compute the results of the transmission coefficient at various incident angles, and also the conductivity and the Fano factor. We discuss the distinguishing signatures of these transport properties in comparison with other semimetals, as well as electrons in normal metals.
Cellular and Molecular Mechanisms of CD8+ T Cell Differentiation, Dysfunction and Exhaustion
Authors: Verdon Daniel J , Mulazzani Matthias , Jenkins Misty R
Published: September 2020

T cells follow a triphasic distinct pathway of activation, proliferation and differentiation before becoming functionally and phenotypically ‘exhausted’ in settings of chronic infection, autoimmunity and in cancer. Exhausted T cells progressively lose canonical effector functions, exhibit altered transcriptional networks and epigenetic signatures and gain constitutive expression of a broad coinhibitory receptor suite. This review outlines recent advances in our understanding of exhausted T cell biology and examines cellular and molecular mechanisms by which a state of dysfunction or exhaustion is established, and mechanisms by which exhausted T cells may still contribute to pathogen or tumour control. Further, this review describes our understanding of exhausted T cell heterogeneity and outlines the mechanisms by which checkpoint blockade differentially engages exhausted T cell subsets to overcome exhaustion and recover T cell function.
The Undervalued Avenue to Reinstate Tumor Suppressor Functionality of the p53 Protein Family for Improved Cancer Therapy - Drug Repurposing
Authors: Zawacka-Pankau Joanna E
Published: September 2020

p53 and p73 are critical tumor suppressors inactivated in human cancers through various mechanisms. Owing to high structural homology, the proteins share many joined functions and recognize the same set of genes involved in apoptosis and cell cycle regulation. p53 is known as the ‘guardian of the genome’ and forms a critical barrier against cancer development and progression. It is mutated in more than 50% of all human cancers and the germline mutations in TP53 predispose to the early onset of multiple tumors in Li-Fraumeni Syndrome (LFS), the inherited cancer predisposition. Despite the ongoing effort, the treatment of cancers harbouring mutant p53 still remains challenging due to late diagnoses and the treatment-related toxicity and marginal benefit upon approval of new therapies. Presently, the efforts focus on activating p53 exclusively, neglecting the potential of the restoration of the p73 protein in tumors. Taken that several small molecules activating wild-type p53 have failed in clinical trials, and mutant p53 reactivating drugs have not been approved yet, there is a pressing need to develop new treatments activating p53 proteins. This review outlines the still despised therapeutic avenue, drug repurposing, which brings hope for the efficient reinstatement of the p53 protein family for improved cancer therapy.
Implementation of a Delayed Prescribing Model to Reduce Antibiotic Prescribing for Suspected Upper Respiratory Tract Infections in a Hospital Outpatient Department, Ghana
Authors: Ghebrehewet Sam , Shepherd Wendi , Panford-Quainoo Edwin , Shantikumar Saran , Decraene Valerie , Rajendran Rajesh , Kushal Menaal , Akuffo Afua , Ayerh Dinah , Amofah George
Published: September 2020

This service improvement project was carried out at LEKMA Hospital, Ghana. Ghana has high levels of antimicrobial resistance (AMR). There is an urgent need to introduce models of care that optimize antibiotic prescribing. Methods Delayed / back-up prescribing is a strategy that could reduce antibiotic use in suspected upper respiratory tract infections. Four different models of delayed / back-up prescribing [no prescription; post-dated prescription (given to patient); post-dated prescription (forwarded to pharmacy); and follow-up appointment for reassessment after 3 days] were implemented in discussion between clinician and patient. Patients were contacted 10 days after their appointment to record compliance, check on their wellbeing, and rate their experience. Results Over a 3-month period (12/2019-02/2020), 142 patients were eligible for delayed / back-up prescribing. The most common clinical diagnoses were sore throat (102/140, 73%), common cold (22/140, 16%) and sinusitis (10/140, 7%). In total, 12 (9%) patients remained symptomatic at day 10, and only one individual in the entire cohort took antibiotics. Most patients (95%) rated their experience as good or very good. Conclusions Delayed / back-up prescribing models can lead to substantial reduction in antibiotic consumption amongst outpatient department patients with suspected upper respiratory tract infections. Delayed / back-up prescribing can be implemented safely in low and middle-income countries.
Patterns in Protein Components Present in Rattlesnake Venom: A Meta-Analysis
Authors: Deshwal Anant , Phan Phuc , Kannan Ragupathy , Thallapuranam Suresh Kumar
Published: September 2020

The specificity and potency of venom components gives them a unique advantage in development of various pharmaceutical drugs. Though venom is a cocktail of proteins rarely is the synergy and association between various venom components studied. Understanding the relationship between various components is critical in medical research. Using meta-analysis, we found underlying patterns and associations in the appearance of the toxin families. For Crotalus, Dis has the most associations with the following toxins: PDE; BPP; CRL; CRiSP; LAAO; SVMP P-I & LAAO; SVMP P-III and LAAO. In Sistrurus venom CTL and NGF had most associations. These associations can be used to predict presence of proteins in novel venom and to understand synergies between venom components for enhanced bioactivity. Using this approach, the need to revisit classification of proteins as major components or minor components is highlighted. The revised classification of venom components needs to be based on ubiquity, bioactivity, number of associations and synergies. The revised classification will help in increased research on venom components such as NGF which have high medical importance.
Predicting Fruit Yield Using Shallow Neural Networks
Authors: Bulanon Duke M , Braddock Trevor , Allen Brice , Bulanon Joseph Ichiro
Published: September 2020

Precision agriculture is a technology used by farmers to help food sustainability amidst growing population. One of the tools of precision agriculture is yield monitoring, which helps a farmer manage his production. Yield monitoring is usually done during harvest, however it could also be done early in the growing season. Early prediction of yield, specifically for fruit trees, aids the farmer in the marketing of their product and assists in managing production logistics such as labor requirement and storage needs. In this study, a machine vision system is developed to estimate fruit yield early in the season. The machine vision system uses a color camera to capture images of fruit trees during the full bloom period. An image segmentation algorithm based on an artificial neural network was developed to recognize and count the blossoms on the tree. The artificial neural network segmentation algorithm uses color information and position as input. The resulting correlation between the blossom count and the actual number of fruits on the tree shows the potential of this method to be used for early prediction of fruit yield.
Application of the Incremental Modal Analysis for Bridges (IMPAb) Subjected to Near-Fault Ground Motions
Authors: Bergami Alessandro Vittorio , Fiorentino Gabriele , Lavorato Davide , Briseghella Bruno , Nuti Camillo
Published: September 2020

Near-fault ground motions can cause severe damage to civil structures, including bridges. Safety assessment of these structures for near fault ground motion is usually performed through Non-Linear Dynamic Analyses, while faster methods are often used. IMPAb (Incremental Modal Pushover Analysis for Bridges) permits to investigate the seismic response of a bridge by considering the effects of higher modes, which are often relevant for bridges. In this work, IMPAb is applied to a bridge case study considering near-fault pulse-like ground motion records. The records were analyzed and selected from the European Strong Motion Database and the pulse parameters were evaluated. In the paper results from standard pushover procedures and IMPAb are compared with nonlinear Response-History Analysis (NRHA), considering also the vertical component of the motion, as benchmark solutions and incremental dynamic analysis (IDA). Results from the case study demonstrate that the vertical seismic action has a minor influence on the structural response of the bridge. Therefore IMPAb, which can be applied considering vertical motion, remains very effective conserving the original formulation of the procedure, and can be considered a well performing procedure also for near-fault events.
Immunomodulatory Effect and Supportive Role of Traditional Herbs, Spices and Nutrients in Management of COVID-19
Authors: Sharma Luxita
Published: September 2020

Corona Virus disease 2019 (COVID-19) is a new strain of coronavirus that causes respiratory illnesses with a start of flu like symptoms. This disease is fatal and is spread all over the world. The Scientist are working day and night to find vaccine or a cure. World Health Organisation has declared COVID-19 as pandemic [1]. In the view of the pandemic many treatments are being tried on the patients and various treatment modalities are being followed, the traditional medicine has shown a major role to manage this disease. The traditional medicines include the use of herbs, nutrition and spices that are freely available in Asian countries. These are used in day to day life by Asian population [2]. In this paper we have compiled and reviewed the role of various herbs and spices such as Oregano, Ashwagandha, Ginseng, Basil, Sage, Curcumin, Fenugreek, Ginger and Garlic in building immunity and also in curing pathogenic invasions based on evidence based researches. As there is no cure available for COVID-19 till now so supportive therapy is playing a major role for the patients to fight with this pandemic. The AYUSH ministry has also promoted the use of above herbs for a patient suffering from this disease. The corona virus is present in respiratory system as shown by different studies and it has different strains. The guidelines laid by the ICMR and WHO shows that use of herbs, spices and nutrients can be helpful to manage this virus by increasing the immunity in patients. Hence we are not claiming any cures but the herbs and spices used in day to day life are very much effective in management of COVID-19. World Health Organisation (WHO) has recognised the use of alternative and traditional medicine in the management of COVID-19 but the herbs should be used in prescribed amounts and overdose of them can be harmful for health [1,3]. Therefore the present article will enlighten the readers about the role of herbs, spices and nutrients in improving the conditions in COVID-19.
Anterior Interosseous Nerve Syndrome Reconsidered
Authors: Krishnan Karthik R. , Sneag Darryl B. , Feinberg Joseph H. , Wolfe Scott W.
Published: September 2020

» Anterior interosseous nerve syndrome (AINS) represents a form of neuralgic amyotrophy (Parsonage-Turner syndrome).

» AINS does not originate from external compression of the AIN in the forearm.

» Fascicular constrictions (FCs) of the median nerve are identified within the anterior interosseous fascicular group at or above the medial epicondyle.

» Spontaneous recovery is not ensured, leaving up to 30% of patients with permanent weakness or palsy.

» Fascicular microneurolysis of the median nerve, performed at or above the elbow, is a treatment option for patients who do not recover spontaneously.
Quién es quién en Morón de la Frontera a inicios de s. XVI: La Casa de Osuna y sus hombres en la villa (I)
Authors: Martín Humanes José María
Published: September 2020

La presente publicación abre una serie de artículos dedicados al estudio prosopográfico de las principales personalidades de Morón de la Frontera en tiempos de los primeros condes de Ureña (ss. XV-XVI). A lo largo de los mismos, a modo de entradas personalizadas, se ofrecerán valiosos datos de archivo e informaciones de diversa procedencia sobre estas figuras, sus entramados familiares, estatutos jurídicos, oficios públicos, patrimonios o participaciones en la escena política cotidiana de la villa. En aquellos casos en los que la documentación lo ha hecho posible, se les ha acompañado de la respectiva representación genealógica y heráldica. En esta primera entrega se abordarán a los hombres de la Casa de Osuna en la villa. Sus delegados.
O ENSINO DE LÍNGUAS BASEADO EM TAREFAS NO ENSINO/APRENDIZAGEM DA ESCRITA EM PORTUGUÊS LÍNGUA SEGUNDA – PROPOSTAS DIDÁTICAS
Authors: Pinto Jorge
Published: September 2020

O objetivo deste artigo é apresentar uma reflexão sobre o Ensino de Línguas Baseado em Tarefas (ELBT), por se considerar que poderá possibilitar o desenvolvimento mais eficaz da produção escrita. Existem vários tipos de tarefas, sendo o objetivo de cada uma resolver dada situação comunicativa, através de uma espontânea troca de sentidos, que tem relação com a vida real e a experiência dos alunos, despertando o seu interesse e aumentando o seu envolvimento na aprendizagem. Os principais problemas que os alunos enfrentam na escrita são: a seleção lexical adequada ao tema; a seleção dos tempos verbais adequados ao contexto; a ortografia e a pontuação corretas; a coerência e a coesão textuais. Como forma de ultrapassar estas dificuldades, propõe-se o ELBT. Assim, num primeiro momento, analisar-se-á a importância do ELBT no ensino das línguas segundas, em geral, e da escrita, em particular, e, num segundo, como parte de um estudo desenvolvido em três escolas secundárias da Praia – Cabo Verde, serão propostas tarefas testadas com êxito em sala de aula, em contexto de língua segunda. Os resultados parciais, baseados num questionário aplicado aos alunos que participaram no estudo, revelam que há maior envolvimento dos alunos nas tarefas de escrita e uma perceção de melhoria desta competência.