bluuebunny/crossref_metadata_2025 huggingface dataset:
Sustainability of transport system: Case study of Greater Mumbai
Authors: Juyal Shikha , Yedla Sudhakar
Published: November 2020

Sustainable transport is about taking holistic approach by considering economic, society and environment along with the mobility and accessibility requirement of people.  In case of Greater Mumbai, there is presence of inequity in provision of transport infrastructure and service. The first part of paper arrives at sustainability indicator by means of compounded economic, social & demographic, land use and transport access indicators. The second part of paper measures the extent of sustainability in various wards of Greater Mumbai.  It was important to study the extent of sustainability by measuring the gap between sustainability & HDI indicator and sustainability & transport access indicator. In terms of transport access, the gap between transport access indicator and sustainability indicator is present in most of the wards of Greater Mumbai. The overall result proves that there is urgent need to address the provision of transport access in most of the wards of Greater Mumbai. Purpose: The main purpose of this paper is to arrive at sustainability indicator and to measures the extent of sustainability in various wards of Greater Mumbai in transport. Methodology: The paper arrives at sustainability indicator by developing compounded economic, social and demographic, land use and transport access indicators. In order to calculate economic, social & demographic, land-use and transport access indicator considered normalized value of each indicators derived from maximum point normalization across all wards. Finally equal weighted average of all indicators was taken to calculate the overall sustainability indicator. To measure the extent of sustainability in various wards of Greater Mumbai was done by comparing aggregate sustainable indicator with HDI indicator and transport access indicator. Result: The overall result proves that there is urgent need to address the provision of transport access in most of the wards of Greater Mumbai. The theoretical contribution: This paper arrives at sustainability indicator by compiling economic, social and demographic, land use and transport access indicators. Practical implications: This paper calculates ward level sustainability in Greater Mumbai and identifies the need to make provision of different transport infrastructure.
Milyen lesz a jövő nemzetközi marketingje a hatalmi átalakulások következtében?
Authors: Hetesi Erzsébet
Published: November 2020

A gazdasági hatalmi átalakulások globális megatrendje kétségtelenül átrajzolja majd a nemzetközi marketing természetét. Rekettye Gábor vitaindítójára reagálva jelen tanulmány a témával kapcsolatban négy kérdést érint. Az első részben a szerző arra keresi a választ, hogy mennyire lehet hinni a trendekre alapozott prognózisoknak, és milyen kockázatokkal kell számolni? A második rész a gazdasági átrendeződés kulturális következményeit, az urbanizációs folyamatot, valamint a középosztály növekvő fogyasztását veszi górcső alá. A következtetések arra hívják fel a figyelmet, hogy a jövő nemzetközi marketingje nem hagyatkozhat csak a most uralkodó trendekre: a változásokra vonatkozóan szcenáriókkal kell rendelkezni.
Determinação de metais pesados (Fe, Mn, Cd, Cu, Co, Cr, Ni, Zn e Pb), matéria orgânica e carbono orgânico no sedimento de áreas de manguezal NO Município de Vigia De Nazaré, NE –PA
Authors: Cavalcante Anny Marysol Souza , Santos Raimundo Nonato Do Espiríto Santo dos
Published: November 2020

A contaminação e avaliação de metais no sedimento de ecossistemas aquáticos é um importante registrador da poluição ambiental ocorrida em locais próximos a áreas urbanas. Desse modo, o estudo investiga caracterizar e quantificar os teores de metais pesados (Fe, Mn, Cd, Cu, Co, Cr, Ni, Zn e Pb), no sedimento de fundo no Furo da Laura, município de Vigia de Nazaré (PA). A área é considerada de grande importância para o complexo hidrográfico, por ser um estuário que recebe contribuição da Baía do Marajó. Foram coletadas nove amostras de sedimento que foram peneiradas na fração argila 63 μm. Foi realizado a pesagem de massa de 0,5g de cada ponto, para ser submetida a digestão ácida. As determinações dos metais foram realizadas por espectrometria de absorção atômica com atomização por chama, extração parcial. As determinações de matéria orgânica e carbono orgânico se utilizaram como referência o método de Walkley-Black. Apenas os resultados pra Pb (P3, P4 e P7) e Ni apresentaram valores acima do limite tolerável estipulado pelo CONAMA 454/12 Nível 1, sugerindo a contribuição antropogênica, cujas prováveis fontes de lançamentos são os efluentes domésticos e industriais do município, e também, as atividades de transporte fluvial, vazamento de combustíveis, óleos e materiais graxos. Recomenda-se que a área seja monitorada para que se possa acompanhar o comportamento desses metais, que apresentaram teores anômalos.
Comorbid infections in spondyloarthritis: a modern view of the problem
Authors: Muravyeva N. V. , Belov B. S. , Baranova M. M. , Korotaeva T. V.
Published: November 2020

The review considers the problem of comorbid infections (CIs) in ankylosing spondylitis and psoriatic arthritis (PsA) as the main nosological entities of spondyloarthritis (SpA). It analyzes the frequency of CIs during therapy with biological agents and targeted synthetic disease-modifying anti-rheumatic drugs. It is concluded that the problem of CI in SpA deserves the closest attention. The review also shows the importance of preventive measures for CI in the treatment of SpA. It is in particular noted that in accordance with the updated guidelines of the European League Against Rheumatism and other rheumatology research associations, all patients with immunemediated inflammatory rheumatic diseases (including SpA) on immunosuppressive therapy are recommended to get influenza and pneumococcal vaccines due to the high risk of death from respiratory tract infections. Moreover, vaccination is indicated even for patients with an expected suboptimal response. The review gives the main points of the recommendations of the Medical Board of the National Psoriasis (Ps) Foundation on the use of recombinant Herpes zoster vaccine in patients with Ps/PsA. There is a need for further investigations of the frequency and pattern of CIs and the impact of new therapy options on the prevalence of CIs in patients with SpA. Determination of the effectiveness and safety of vaccination in this patient population should become an important area for future investigations.
Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefits
Authors: Filatova E. S. , Karateev A. E.
Published: November 2020

Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) contain a relatively low dose of their active ingredient and are intended for short-term use (for 3–5 days). They are effective and convenient in the treatment of musculoskeletal pain in many clinical situations in rheumatology practice. Over-the-counter naproxen 275 mg has a proven analgesic efficacy, with its action duration of up to 12–15 hours after single-dose administration, and a favorable safety profile. It can be used successfully for the management of exacerbations of osteoarthritis, short-term episodes of pain with a stable course of autoimmune inflammatory rheumatic diseases, with acute nonspecific back pain and at the onset of periarticular soft tissue pathology. With allowance made for the national guidelines for the use of NSAIDs, this drug can be prescribed for a short time as an analgesic therapy in patients at high risk for cardiovascular events. It is of particular value for outpatient practice, since the patients can freely purchase and use it in accordance with the principles of responsible self-medication.
Successful use of the interleukin-17A inhibitor (ixekizumab) in the treatment of psoriatic arthritis
Authors: Dadalova A. M. , Vasilenko E. A. , Samigullina R. R. , Mazurov V. I.
Published: November 2020

Psoriatic arthritis (PsA) is a chronic immune-mediated disease from a group of spondyloarthritis, which is characterized by damage to the musculoskeletal system with a wide range of different clinical manifestations and is usually associated with psoriasis. Activation of the interleukin (IL) 23/IL17 axis plays a key role in the pathogenesis of PsA and psoriasis. When non-steroidal and synthetic disease-modifying antirheumatic drugs are insufficiently effective, biological drugs are recommended. In recent years, there have been considerable advances in PsA treatment with tumor necrosis factor-α (IFN-α) inhibitors and IL-12/23 inhibitors. However, in some cases, this therapy fails to provide the desired effect and a search for new treatments for PsA seems to be an urgent task. The paper desctibes a clinical case demonstrating the efficacy of the IL17A inhibitor ixekizumab in a patient with high PsA activity and recurrent uveitis in both eyes. Ixekizumab therapy resulted in positive changes as the reduced severity of articular syndrome and psoriasis and normalization of acute phase parameters. Assessing the activity of PsA over time when using ixekizumab during a year showed an average decrease in ESR from 72 to 19 mm/h, in CRP from 162.1 to 0 mg/L, BSA from 51 to 0.25%, PASI from 43. 6 to 0, DAPSA from 78.2 to 2, ASDAS-SRB from 5.11 to 1.12, BASDAI from 4.85 to 1, BASFI from 5.3 to 0.7, BASMI from 5.0 to 2.6, MASES from 6 to 0, LEI from 2 to 0, SPARCC from 6 to 0, and NAPSI from 28 to 8. Thus, this clinical case is an example of successful treatment with the IL17 inhibitor ixekizumab for PsA with recurrent uveitis in the patient who has previously received three drugs from the TNFα group without any effect.
Long-term efficacy and safety of netakimab in the treatment of ankylosing spondylitis: results of Phase III international, multicenter, randomized double-blind clinical trial BCD-085-5/ASTERA
Authors: Mazurov V. I. , Erdes Sh. F. , Gaydukova I. Z. , Dubinina T. V. , Pristrom A. M. , Kunder E. V. , Soroka N. F. , Kastanayan A. A. , Povarova T. V. , Zhugrova E. S. , Plaksina T. V. , Shesternya P. A. , Kropotina T. V. , Antipova O. V. , Smolyarchuk E. A. , Tsyupa O. A. , Abdulganieva D. I. , Lapshina S. A. , Krechikova D. G. , Gordeev I. G. , Nesmeyanova O. B. , Ilivanova E. P. , Strelkova A. V. , Eremeeva A. V. , Zinkina-Orikhan A. V.
Published: November 2020

Netakimab (NTK) is a humanized anti-interleukin-17A monoclonal antibody. To date, the drug has been approved to treat ankylosing spondylitis (AS), psoriatic arthritis, and plaque psoriasis. The paper gives the data obtained during 52-week follow-up of AS patients in the phase III ASTERA study.

Objective: to study the efficacy and safety of NTK when used long in patients with active AS.

Patients and methods. The investigation enrolled 228 patients with active AS, in whom nonsteroidal anti-inflammatory drugs or biological agents were ineffective. The patients were randomized in a 1:1 ratio to receive NTK 120 mg or placebo. The drug was administered subcutaneously at weeks 0, 1, 2, and then once every 2 weeks. Patients who received placebo and achieved a 20% improvement according to the ASAS criteria (ASAS20) were excluded from the study at week 16. At this week, patients who took placebo and did not achieve an ASAS20 response were switched to subcutaneous NTK at 120 mg dose once every two weeks. The follow-up period was 52 weeks.

Results and discussion. Patients with active AS who received NTK were more likely to respond to treatment than those who took placebo. The proportion of people who achieved 40% improvement (ASAS40) during treatment with NTK increased throughout the follow-up period and amounted to 80.7% at week 52. Positive changes were achieved in all used clinical and laboratory parameters of AS activity. There was also a decrease in inflammatory changes, as shown by magnetic resonance imaging (MRI). The adverse events (AEs) were mainly laboratory abnormalities and upper respiratory tract infections. Treatment-related AEs were recorded in no more than one third of patients and they were mild to moderate. Severe AEs were singular.

Conclusion. Response to NTK therapy generates in the first weeks of drug use and increases throughout a year. The safety profile of NTK when used long is generally favorable.
Virtual exchange in teacher education: is there an impact in teacher practice?
Authors: Dooly Melinda
Published: November 2020

This text presents the results of surveys and interviews of Former Students (FSs) who have taken part in a teacher education course that began in 2004 (still on-going) and that includes Virtual Exchange (VE). The study aimed to look at the impact of two teacher education courses, imparted collaboratively between geographically-distanced universities for over a decade. The course design aims to introduce VE, both theoretically and empirically, as an approach to foreign language teaching in primary and secondary schools. The data are drawn from an online survey as well as in-depth interviews with FSs enrolled in the course between 2004 and 2015. The findings indicate that a significantly high percentage of the FSs who had been exposed to VE had been involved in or intended to implement VE in their own teaching and that the course had provided them with the knowledge and confidence to do so.
Modelos cognitivos y globalización en el filme La llegada
Authors: Pardo Fernández Rodrigo , Morales Campos Arturo
Published: November 2020

Todo conjunto de ideas puede entenderse, bajo presupuestos semióticos, como una estructura textual y, a la vez, como un modelo cognitivo. El análisis de ese segundo elemento permite encontrar nociones clave (connotaciones) para el acceso a gran parte del significado de dicho conjunto de ideas. En el presente trabajo, abordaremos el texto fílmico La llegada(2016), en el que localizaremos la participación de determinados modelos cognitivos y sus respectivas nociones fundamentales. Este procedimiento nos permitirá acercarnos a niveles profundos de significación que refieren diversas ideologías imperantes en la cultura occidental cercanas al momento de producción del filme. De alguna manera, la participación ideológica, implícita en el relato, cumple con los presupuestos básicos de la globalización y, por ende, con las reglas del mercado cinematográfico. Nos referimos a la imposición de modelos occidentales para la resolución de un conflicto mundial.
Imaging of Dicamba Using Laser Ablation Electrospray Ionization Mass Spectrometry in Cabbage Leaves
Authors: Malys Brian , Rumbelow Steve , Wall Jason
Published: November 2020

The distribution of herbicide active ingredients in plant tissue, after deposition, is valuable information when assessing the influence of formulation on efficacy. Typical techniques for assessing herbicide movement require time-consuming methods that involve collecting and isolating cuticles for Franz cells or the application, homogenization, and extraction of plant tissue. Franz cells speak only to cuticular penetration, while homogenization loses spatial resolution of analyte distributions. A key advancement in recent years is the use of mass spectrometry for imaging samples, which provides a visualization of the spatial distribution of analytes within samples. Here, laser ablation electrospray ionization mass spectrometry imaging was used to image the distribution of herbicides within plant material after application from droplets. In this technique, an herbicide is applied to plant tissue, such as a whole leaf, and allowed to spread and penetrate the surface. The exposed area is excised and placed into the ionization device, without the need for sample preparation such as cross-sectioning or homogenization and extraction. A laser is used to ablate material from specific locations, and ions are generated through entrainment in an electrospray plume and directed into the inlet of a mass spectrometer. Spectra are collected, and mass spectrometry images are extracted using characteristic ions of a target. After the application of three dicamba solutions over 2 and 24 h, it was determined that no significant penetration of dicamba occurred for any of the three solutions over 2 h. Over 24 h, two treatments containing 0.5% of polysorbate variants produced detectable penetration of dicamba, while the treatment containing only dicamba produced no measureable penetration of dicamba.
МЕТОДИЧНІ ПІДХОДИ ДО ВИОКРЕМЛЕННЯ ТА ІДЕНТИФІКАЦІЇ СІЛЬСЬКИХ ТЕРИТОРІЙ (У КОНТЕКСТІ ІМПЛЕМЕНТАЦІЇ ЄВРОПЕЙСЬКОГО ДОСВІДУ)
Authors: СТОРОНЯНСЬКА Ірина , ЗАЛУЦЬКИЙ Іван
Published: November 2020

Наголошено на відсутності в законодавстві України юридичних норм щодо методологічно-правових критеріїв ідентифікації сільських територій на окремих ієрархічних рівнях адміністративно-територіального устрою України, конкретності, послідовності, передбачуваності та дієвості державної політики розвитку сільських територій. З позиції імплементації в Україні сучасного європейського інструментарію виокремлення сільських територій запропоновано варіант правової дефініції терміна «сільська територія», яким конкретизовано критерії ідентифікації сільської території, зокрема:• на рівні місцевої адміністративної одиниці (LAU): густота населення, як правило, є меншою за 300 осіб на 1 км2; частка міського населення місцевої адміністративної одиниці не перевищує 50% (сільське населення становить понад 50%), за винятком місцевої адміністративної одиниці, що є зоною сполучення (впливу) міста з населенням не менш як 50 тис. осіб, в якому працевлаштовано щонайменше 15% жителів місцевої адміністративної одиниці;• на субрегіональному (районному) рівні (NUTS-3): густота населення, як правило, є меншою за 300 жителів на 1 км2; частка міського населення району є меншою від 50% (щонайменше 50% сільського населення), якщо до складу району не входить місто з понад 200 тис. жителями, або щонайменше 25% від загальної чисельності населення району.З урахуванням наявних істотних перешкод методологічного впровадження європейського інструментарію ідентифікації сільських територій обґрунтовано й апробовано класифікацію територій адміністративних районів України як малих регіонів рівня NUTS-3 та аналогів місцевих адміністративних одиниць LAU за наявними статистичними даними, з виокремленням переважно міських, проміжних і переважно сільських територій, зокрема, останніх за проєвропейськими критеріями.
Pregnancy outcomes in women with human immunodeficiency virus infection
Authors: Gámez-Belmonte A. , López-Ruz M. A.
Published: November 2020

Introduction: Since the appearance of the first cases of human immunodeficiency virus infection, a great improvement in its treatment and control has been achieved, turning it into a chronic disease. This also occurs in the treatment and monitoring of pregnant women who carry the virus, who also pass on the disease to their children less frequently. In this study the monitoring and results of the pregnancy of women who carry the infection and are monitored in the University Hospital Virgen de las Nieves in Granada were analysed.
Methods: To this end, the medical records of the women who met these requirements were collected, and the variables that affect the control of the infection and its transmission to the child were studied. The cases with mother-to-child transmission and the ones in which the mother were infected perinatally were studied more thoroughly.
Outcomes: The results obtained are favourable when it comes to the control of the HIV infection of these patients, especially after the introduction of the zidovudine as a prophylaxis during labour. There have not been any new cases of mother-to-child transmission since 1997.
Conclusions: Pregnancies in women with human immunodeficiency virus infection were managed efficiently with good outcomes in general, and most of the women gave birth seronegative children.
Improving the quality of life in the postpartum period: reduce the incidence of hemorrhoids and its complications
Authors:   SI «Institute of Pediatrics, Obstetrics and Gynecology name after academic O.M. Lukyanova NAMS of Ukraine», Kyiv, Davydova Yu.V. , Ogorodnyk A.O. ,   SI «Institute of Pediatrics, Obstetrics and Gynecology name after academic O.M. Lukyanova NAMS of Ukraine», Kyiv, Lymanska A.Iu. ,   SI «Institute of Pediatrics, Obstetrics and Gynecology name after academic O.M. Lukyanova NAMS of Ukraine», Kyiv
Published: November 2020

There are insufficient data in the literature on the actual frequency and prevalence of hemorrhoids among the general population. The incidence of hemorrhoids during pregnancy and in the postpartum period, according to various authors, varies considerably: from a third of women to 86%. The frequency of thrombosis of external hemorrhoids and cracks of the anus in the postpartum period is 25–33%. The aim is to analyze data on the frequency of hemorrhoids during pregnancy and within postpartum period, as well as data on the impact of perianal disorders on the quality of life of women; substantiate recommendations for improving the quality of life of such women. Materials and methods. The analysis of databases from medical research PubMed, MedScape, NCBI by keywords: hemorrhoids, pregnancy, postpartum period, causes, diagnosis, treatment, quality of life. 2000 publications were found, of which, according to relevant information, 4 were selected for analysis. The selection criteria were: cohort of subjects (at least 200 people), prospectiveness of observation (pregnancy and postpartum period), availability of data on medical examination. The information-analytical method and content-analysis are used. Results and conclusions. Hemorrhoids are a frequent complication during pregnancy and in the postpartum period. Perianal disease reduces the quality of life of women during pregnancy and in the postpartum period and requires improved care recommendations. Reparon Herbal, which contains herbal substances and sucralfate, according to the instructions, can be used during pregnancy and in the postpartum period to reduce the clinical manifestations of hemorrhoids, which will improve the quality of life of such women. The authors declare no conflict of interest. Key words: hemorrhoids, pregnancy, postpartum period, causes, diagnosis, treatment, quality of life.
Indicators of humoral immunity of patients with neonatal sepsis under different conditions of environmental pollution of parents' places of residence
Authors:   HSEE of Ukraine «Bukovinian State Medical University», Chernivtsi, Vlasova O.V.
Published: November 2020

The aim is to determine the indicators of humoral immunity of patients with neonatal sepsis under different conditions of environmental pollution of their parents' places of residence. Materials and methods. 260 patients with neonatal sepsis born to parents who lived in different environmental conditions were examined. An environmental risk factor (CER) was proposed as a group-forming feature of a comprehensive assessment of the long+term load of anthropogenic air, water and soil pollution in the regions of the region on the body of parents of newborns, taking into account the environmental situation in regional centers. Results. The level of IgA in the serum of patients with neonatal sepsis in group I was 0.82±0.11 g/l against 1.54±0.23 g/l (p<0.05) in group II, the level of IgG in children I groups — 4.27±0.45 g/l against 6.67±0.77 g/l (p<0.05) of group II. The decrease in IgM content had no significant differences, but there was a tendency to reduce its level in children of group I. Conclusions. The constant residence of parents in areas with a high risk of adverse effects of these environmental factors on their body (ERF<2.0) contributed to a decrease in the level of immunoglobulins A, M, G in the serum of patients with neonatal sepsis, compared with newborns whose parents lived in areas with a low risk of adverse effects (ERF<2.0), and were more likely to have severe neonatal sepsis. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of these Institutes. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the author. Key words: neonatal sepsis, pollution, immunoglobulins.
A modern view of medical accompaniment of the colic in neonate (literature review)
Authors:   Danylo Halytsky National Medical University of Lviv, Ukraine, Kiselova M.M. , Moshtuk O.S. ,   Danylo Halytsky National Medical University of Lviv, Ukraine
Published: November 2020

Many infants who represent one of the nosological units that refined functional digestive disorders remain an urgent problem of high frequency of parents' referrals to neonatologists, pediatricians, and general practice — family doctors. Existing studies of a number of hypotheses regarding the etiology, mechanisms of origin, and different approaches to the treatment of colic in infants indicate the relevance of this problem. The article presents current literature data, highlighting the main complaints of parents with suspected colic in a child, presents an analysis of the main causes of this functional bowel disorder, some knowledge about the etiopathogenetic mechanisms of colic, modern components of medical care in infants. Emphasis is placed on the existing ambiguous hypotheses that explain the pathogenetic processes in the body of infants with colic. The focus is on the fact that colic remains a diagnosis of exclusion from other functional bowel diseases. It is noted that the basis of medical support of colic are personalized measures aimed at reducing the severity of pain and choosing the optimal tactics for managing the baby in the period between attacks (background correction), taking into account the existing causes and mechanisms of colic. No conflict of interest was declared by the authors. Key words: functional disorders of digestion refinement, infants, colic in neonate, diagnosis, management.
Clinical case of effective treatment of gestational pemphigoid with intravenous immunoglobulins
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Yavir V.S. ,   Municipal non-profit enterprise Kyiv city maternity hospital No.5, Ukraine, Spichak K.O. ,   Bogomolets National Medical University, Kyiv, Ukraine,   Municipal non-profit enterprise Kyiv city maternity hospital No.5, Ukraine, Berestovoy V.О. ,   Bogomolets National Medical University, Kyiv, Ukraine,   Municipal non-profit enterprise Kyiv city maternity hospital No.5, Ukraine, Martych A.M. ,   Bogomolets National Medical University, Kyiv, Ukraine,   Municipal non-profit enterprise Kyiv city maternity hospital No.5, Ukraine, Sokol I.V. ,   Bogomolets National Medical University, Kyiv, Ukraine,   Municipal non-profit enterprise Kyiv city maternity hospital No.5, Ukraine, Liashko M.B ,   Bogomolets National Medical University, Kyiv, Ukraine,   Municipal non-profit enterprise Kyiv city maternity hospital No.5, Ukraine, Govsieiev D.O. ,   Bogomolets National Medical University, Kyiv, Ukraine,   Municipal non-profit enterprise Kyiv city maternity hospital No.5, Ukraine
Published: November 2020

Gestational pemphigus — is a rare autoimmune condition that manifest during pregnancy. This pathology was described for the first time in 1827 by the Karl Martius, but until now remains insufficiently studied and as a result, difficulties arise in the differential diagnosis and treatment. Clinical manifestations of the disease characterized by the appearance of a polymorphic rash on the skin and mucous membranes. In patients with impaired immune tolerance pemphigus can be complicated by hyperactivation of the immune system. To date, pregnancy is not considered as a factor that can aggravate the course of pemphigus, since during pregnancy the disease can worsen, enter into complete remission, or remain unchanged. In the literature, there is information about the manifestation of pemphigus in puerperium after rapid decrease of corticosteroid hormones in serum. The clinical course of gestational pemphigus is variable and can lead to diagnostic failures. The diagnosis usually made according to the clinic, histopathology and laboratory findings. In this case report we describe a case of diagnosis and treatment of gestational pemphigoid, refractory to corticosteroid therapy. Clinical improvement and recovery achieved after a course of high doses of intravenous immunoglobulins. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of these Institutes. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: pemphigoid, pregnancy, autoimmune disease, intravenous immunoglobulin.
La influencia pedagógica de la amistad en la educación del interés
Authors: Pérez-Guerrero Javier
Published: November 2020

El objeto de este artículo es explorar la relación entre la amistad y la educación del interés. El interés es un radical humano que debe ser objeto de especial atención educativa por su estrecha vinculación con la actitud moral. Pero para lograr un crecimiento educativo del interés que vaya más allá de su proliferación trivial conviene que se produzca cierta igualación entre educador y educando que es propia de la amistad. Conseguir un crecimiento del área de interés de los más jóvenes hasta que abarque los más valiosos y universales del ser humano es un objetivo educativo prioritario, pero que parece difícil de conseguir si no existe amistad entre educador y educando.
Intención de abandono y abandono durante el primer curso de Formación Profesional de Grado Medio: un análisis tomando como referencia el concepto de implicación del estudiante ("student engagement")
Authors: Cerdà-Navarro Antoni , Sureda-García Inmaculada , Salvà-Mut Francesca
Published: November 2020

Este artículo analiza la intención de abandono y el abandono durante el primer curso de Formación Profesional de Grado Medio (FPGM) en función de siete factores relacionados con el concepto de implicación del estudiante (IE) o student engagement (SE). Los datos analizados provienen de un cuestionario basado en el concepto de IE aplicado a una muestra de 1.030 estudiantes matriculados en el primer curso FPGM. Respecto a la intención de abandono, las perspectivas profesionales fueron el factor con mayor peso predictivo. Respecto al abandono durante el primer curso, los factores con mayor peso fueron las relaciones con el profesorado y la implicación en el trabajo escolar. Los resultados sugieren que las perspectivas profesionales son muy importantes para vincular al estudiante con la profesión estudiada, pero es necesario que éstas se complementen con implicación en las tareas escolares y buenas relaciones con el profesorado para reducir el riesgo de abandono. La importancia del artículo reside en la escasez de trabajos empíricos focalizados en el abandono que se produce en FPGM y en su utilidad para fundamentar intervenciones dirigidas a reducir el abandono.
Evaluation of the Effectiveness of the Emotional Education Program EMO-ACTION within a Preschool Setting
Authors: Fernández-Hawrylak María , Heras-Sevilla Davinia , Cepa-Serrano Amaya
Published: November 2020

The effectiveness of the Emotional Education Program EMO-ACTION (EMO-ACCIÓN) in the development of emotional skills and emotional strategies is evaluated, as well as empathy and problemsolving skills among preschool students. A sample of 123 children were enrolled in the 2nd year of preschool education, aged between 4 and 5 years old. A design of repeated pre-test/post-test measurements was applied to an experimental group (60 children) and a control group (63 children). The Recognition, Regulation, Empathy and Problem-Solving Scale (RRER) was administered before and after the educational intervention. The results confi rm that the program had a positive impact on the development of emotional skills in the children that took part in it. A significant increase was noted in emotional recognition, in emotional regulation, and in the identification, and resolution of problems.
Church Reform of Peter I: Source Study Aspect (According to the Materials of the Vologda Archbishops House of St. Sophia)
Authors: Bashnin Nikita
Published: November 2020

Introduction. The inventory of buildings and property are an accounting document. The largescale description of the lands and property of the spiritual patrimony of 1701–1705 carried out within the framework of the Church Reform of Peter I should be considered as a stage in the control of the state over the material welfare of the Church.

Materials. Inventories of bishops houses and monasteries were found in the central and regional archives. A number of documents of the early 18th century were published.

Analysis. Different census takers carried out descriptions of the patrimonies of the Vologda Bishops house in five regions of the country, which indicates applying the uyezd by uyezd principle of the description of the regions. The comparison of the texts shows that census books of the patrimonies of the Vologda Bishops house of 1701–1702 were primary in relation to the census of economy (statements) of the Vologda Bishops house in 1702–1703. An inventory of the Bishops Treasury was also made.

Results. The comparison of three censuses (patrimony, economy, treasury) gave state documents on the basis of which it was possible to make a complete picture of the economy and property of the Vologda house of St. Sophia. In this regard, a complete secularization of Church possessions actually took place, however it was not fully formalized legally.
« U’dzazi na miko ». Enfantement et proscriptions en contexte mahorais à La Réunion
Authors: Ahmed Zakia
Published: November 2020

Cet article a pour objectif d’analyser, à L’île de la Réunion, les représentations de la procréation et les prescriptions propitiatoires présentes, durant leur grossesse (hamili), chez les femmes mahoraises en contexte d’immigration[^1]. Notre réflexion s’articule autour de deux axes : le premier analyse les représentations de la conception et les analogies avec le monde végétal. Le second analyse les logiques des prescriptions. Elle s’appuie sur des données ethnographiques collectées lors d’enquêtes de terrain effectuées, depuis 2011, par observation in situ, auprès de personnes mahoraises résidant à La Réunion et à Mayotte.
Une histoire d’annonces. Temporalités et manières de faire d’hier à aujourd’hui
Authors: Rollet Catherine
Published: November 2020

Annoncer la naissance d’un enfant a toujours représenté un moment fort de la vie des familles puisque cette annonce sort l’événement de la sphère familiale et du lignage pour le rendre public. Cette annonce peut être précédée par plusieurs autres, celle de la grossesse, du sexe présumé, espéré ou connu de l’enfant à venir, de son prénom. Autant d’étapes dans la publicisation de la naissance qui appellent l’attention des historiens, des sociologues et plus généralement des sciences sociales. Dans cet article, nous tenterons d’une part une synthèse, très partielle, des pratiques de ces annonces au cours des XVIIIe-XXe siècles pour aborder dans une dernière partie les manières actuelles de passer de l’intime au « public » au travers d’une enquête récente menée en France. Nos questions de recherche peuvent être résumées de la façon suivante : quelles temporalités hier et aujourd’hui, les parents suivent-ils pour annoncer la naissance future de leur enfant ? A quel cercle familial et social font-ils cette ou ces annonces ? Enfin, existe-t-il une hiérarchie dans l’annonce, certains faits étant révélés avant la naissance, d’autres réservés à l’après naissance ?
Les mutations de l’accouchement aux Etats-Unis du XVIIIe au XXe siècle
Authors: Morel Marie-France
Published: November 2020

L’histoire de la naissance aux Etats-Unis a-t-elle suivi les mêmes évolutions qu’en Europe ? Partiellement oui : jusque vers 1850, comme en Europe, la plupart des femmes américaines accouchent à la maison avec une sage-femme. Après 1850, commence une histoire singulière : peu à peu, les sages-femmes à domicile sont évincées par des médecins ; en 1900, 90% des naissances ont encore lieu à domicile, mais les sages-femmes ne surveillent plus que 50% des accouchements et disparaissent peu à peu. A partir de 1938, l’accouchement hospitalier suivi par des obstétriciens et sous anesthésie générale devient la norme. Comment la disparition des sages-femmes américaines a-t-elle été possible ? A-t-elle entraîné des résistances ? Quels en ont été les acteurs et les étapes ? Les nouveautés venues d’Europe ont-elles influencé ces mutations ? Où en est-on aujourd’hui ?
Pour une prise en soins globale et intégrative
Authors: Brandt Pierre-Yves
Published: November 2020

La tâche d’accompagnement spirituel en milieu de santé est en pleine transformation dans nos sociétés occidentalisées. Différents signes en sont l’expression. Dans le monde hospitalier, tout d’abord, où les aumôniers tendent en de nombreux endroits à devenir des accompagnants spirituels dont l’appartenance confessionnelle n’est plus affichée et dont les compétences sont mises au service de tous. Dans les dispositifs de soins envisagés plus largement, ensuite, où d’autres acteurs présents dans ces dispositifs (médecins, infirmières, assistants sociaux, psychologues, etc.) cherchent comment intégrer la spiritualité dans les soins. Il en résulte divers modèles de prise en soins de la spiritualité dont la mise en œuvre s’étend hors du monde des hôpitaux. On en trouve des expressions dans des établissements qui accueillent des personnes âgées, par exemple. Plus récemment, des expériences en cours cherchent également comment intégrer la spiritualité dans les soins à domicile. Toutes ces démarches invitent à préciser ce que l’anglais désigne par « spiritual care ». C’était notamment l’enjeu du colloque international intitulé « Clinique du sens » qui s’est tenu à l’Université de Lausanne le 14 et 15 novembre 2019. Le texte qui suit propose quelques pistes de réflexion en vue d’une prise en soins globale et intégrée de la personne souffrante. Ces pistes ont pour but de baliser le débat sous-jacent aux diverses interventions qui ont pris place durant ce colloque.
Health care chaplaincy in the Nordic countries. Transformations and perspectives
Authors: Danbolt Lars Johan , Stifoss-Hanssen Hans
Published: November 2020

In this article we present some developmental patterns in the 100 years long history of of health care chaplaincy in the Nordic countries, particularely in Norway. We argue that a shift is gradually taking place from what can be regardes as a religious service model to an existential care model. This can be seen within the context of specialization and professionalization both in health care and chaplaincy, as well on the background of pluralization in society. We point at some challenges for chaplaincy regarding delimitation and the relationships between religious and secular anchoring of chaplaincy, the routines for referrals to chaplains, implementation of chaplaincy and inter-disciplinary work in hospitals, and the need for continuous work on knowledge development and research
Le concept de la dignité inaltérable de la personne humaine et ses implications en psychothérapie
Authors: Parpan-Dericum Christine
Published: November 2020

Partant du concept de la dignité humaine j’aborde au niveau théorique de l’analyse existentielle de Frankl son ancrage dans la définition de la personne humaine par trois dimensions : dimension biologique, dimension psychique (et sociale), dimension noétique. Par sa dimension noétique l’être humain se définit comme une personne libre à s’ouvrir au sens de sa vie et d’assumer la responsabilité de ses choix. Liberté et responsabilité définissent un espace libre et ouvert où la rencontre entre la thérapeute et son client a lieu comme une rencontre entre deux personnes branchées au sens et aux valeurs de leurs vies respectives. Au niveau pratique — thérapeutique — la logothérapie demande au psychothérapeute certaines attitudes ou approches bien définies, garantes du respect du client : une approche respectueuse, valorisante, sensible et intuitive, claire et bienveillante, franche et authentique, pleine d’humour et d’amour. L’accent y est mis sur une vue différentielle par rapport à d’autres écoles de psychothérapie, notamment l’approche Rogérienne et la Psychologie Positive.
Subvertendo Gênero: O Lugar da Não-binaridade Numa Análise Discursiva de Conteúdos Midiáticos
Authors: Lemos Patricia Mendes , Andrade Anne Graça de Sousa , Cardoso Bianca Maria Lima
Published: November 2020

As questões de gênero têm despontado inúmeras discussões ao longo da história nas diferentes sociedades. Na contemporaneidade, as diferentes designações de gênero encontradas, têm provocado a necessidade premente de pesquisas aprofundadas que compreendam o fenômeno e apontem intervenções ante a sua complexidade. Na presente pesquisa, buscou-se investigar a construção histórica e cultural das identidades de gênero, a partir das noções binárias de homem/mulher, pautadas nos estudos de Judith Butler (2013) e Michel Foucault (1988; 2009), construindo com isso questionamentos frente às representações sociais e aos modos de identificações e expressões sobre o tema. Traçou-se como objetivo compreender o lugar não-binário de identidade(s) de gênero a partir da análise de mídias virtuais, assim como analisar os discursos produzidos sobre esse lugar de identificação não-binária, além de apreender as dimensões políticas de representação dos discursos acerca da não-binaridade de gênero. Para tanto, utilizou-se uma metodologia de cunho qualitativo, a análise de discurso de Bardin (1977/1979), que viabilizou a apreensão de categorias teóricas das significações dos discursos acessados nas plataformas de blogs, acerca dos modos de compreensão da não-binaridade de gênero. Como resultados obtidos foram esboçadas duas categorias teóricas: 1. Significados não-binários de gênero: construções quanto aos termos descritivo e identitário; e 2. Ser “não-binário”: buscando definição para uma indefinição? Inferiu-se da investigação considerações relevantes sobre os posicionamentos discursivos quanto aos seus significados como termos e designações identitárias, quanto ao lugar de fala dos sujeitos, e quanto a uma dimensão ético e política necessária para a convivência entre os diferentes gêneros.
Modern Directions of Forensic Experts Primary Training
Authors: D'iakonova Oksana G.
Published: November 2020

No type of legal proceedings is complete without the involvement of experts for the production of expert research or specialists for consultation. In this regard, the question of determining the competence of these subjects by persons conducting the process who do not have special knowledge in the field in which the knowledgeable person specializes is very acute. The author determines the competence of the forensic expert and enumerates other requirements to the expert as a participant in the proceedings. The formation of competence is primarily influenced by the level of training, education of an expert or specialist. The main attention focuses on the disclosure of the main ways of initial training and retraining of forensic experts at the present stage: the traditional way of experts training; specialization in the specialty “Forensic examination”; master’s degree in programs of expert specialties. The existing types of training and retraining of forensic experts in Russia and some foreign countries, including the member States of the Eurasian economic Union (EEU), are analyzed. The traditional way of training of forensic experts and training under the program of specialization are revealed proceeding from historical conditionality and necessity of training of specialists for implementation of forensic activity. The positive and negative features of the training areas are highlighted, taking into account their impact on the formation of the competence of the forensic expert. The author emphasizes the need to develop existing forms of initial training of forensic experts, taking into account the advantages and disadvantages of each of them. The study concludes that it is necessary to apply the subjective criterion in order to determine the effective form of training of forensic experts
Heterosis and Combining Ability Through Line x Tester Analysis for Yield, Oil and High Oleic Acid Characters in Sunflower ( Helianthus annuus L.)
Authors: GÖKSOY Abdurrahim , ÖZTÜRK AKAR Leyla , YANIKOĞLU Semra , KIZIK Sezgin
Published: November 2020

This research was conducted in the southern Marmara region of Turkey during 2017-2018 growing season in order to study genetical structure of a hybrid population obtained from three CMS (cytoplasmic male sterile) lines and four pollen tester (restorer) lines with mid or high oleic acid content and to determine general combining abilities (gca) of parental lines, specific combining abilities (sca) of hybrid combinations and their hybrid performances. The field experiments were designed in a randomized complete block with three replications. According to the results, male parents AGR2 and AGR4 considered as good general combiners for developing increased seed and oil yields in sunflower hybrids, although there were not good general combiners in female parents for the same traits. CMS3 x AGR4 test hybrid, which has high oleic acid content, has been determined to be a promising hybrid variety candidate with its high seed and oil yields, high oil content and oleic acid content. However, although the SCA effects of CMS1 x AGR2 and CMS3 x AGR2 test hybrids were not significant for seed and oil yields, it was concluded that they were promising hybrids with high yield, oil content and mid oleic acid content. It was determined that both additive and non-additive gene effects were effective for yield and some important yield components in the hybrid population studied. The values of heterosis and heterobeltiosis values ranged from 10.8 to 728.9 % and -20.1 to 608.8 % for seed yield, respectively. Similarly, positively high and significant heterosis and heterobeltiosis values were obtained in the oil yield.
EFFECTS OF ANİMAL GRAZİNG ON FAVORABLE FORAGE YİELD AND QUALİTY OF RANGELANDS WİTH DİFFERENT SLOPE
Authors: SEVEROĞLU Sedat , GULLAP Mehmet
Published: November 2020

This study conducted between 2016 and 2017 in the Kosk Village of Yakutiye District of Erzurum Province on rangeland sites with 4 different slopes (0-10%, 10-30%, 30-60 and 60% and above). In the research, current favorable forage yield and some forage quality characteristics of rangeland sites with different slope degrees were investigated. It was determined that the forage yield of rangeland sites decreased in steep slope rangeland sites and increased in slightly sloping rangeland sites. It was determined that the effect of different sloping degrees on some forage quality was important. Slightly slope rangeland sites, forages had higher crude protein content, while steep slope rangeland sites had higher ADF and NDF ratio. Also, it was calculated that the Relative Feed Value (RFV) in the rangelands decreased due to the increase in slope. According to the obtained results, it reveals the necessity to practice appropriate management such as the proper intensity of grazing, especially in sloping areas to ensure sustainable rangeland use.
NEW POTATO BREEDING CLONES FOR REGIONAL TESTING IN WESTERN TURKEY
Authors: OZTURK Gulsum , YILDIRIM Zihin
Published: November 2020

Crosses were made between 4 potato genotypes and the registered variety Nif in 2015. The F1 seeds obtained from these crosses were grown in pots in the greenhouse to obtain potato clones. The clones selected were grown in seedbeds in 2016 and clones with high yield and tuber number were selected. Selected clones were grown in the field and selection was applied for high yield and yield components. The results obtained could be summarized as followings:

There were significant variation among the clones and some of them had higher yield than that of the control genotypes. The following 20 clones were selected for the regional yield trials: 3, 21, 184, 185, 194, 195, 196, 202, 204 (Agria x Nif); 89, 90 (6/7 Clone x Nif); 205 (Juwel x Nif) and 153, 159, 160, 163, 164, 174, 176, 177 (Bettina x Nif).