bluuebunny/crossref_metadata_2025 huggingface dataset:
INVESTIGATION OF FIT OF THE INDIVIDUAL ABUTMENT TO THE VARIOUS PLATFORMS OF IMPLANTS ON SAGITTAL SECTION
Authors: Саркисян Константин , Sarkisyan Konstantin , Стрижакова Мария , Strizhakova Maria , Стрижаков В. , Strizhakov V.
Published: August 2019

Introduction. Modern implant systems have different types of connections between the implant and the abutment, in the area of which a microgap can be constructively formed, as a result of which dentists are faced with a loss of bone tissue and inflammatory processes in the area of dental implants.

Objectives ― assessment of the accuracy of the marginal fit of an individual abutment to the implant platform on a sagittal slice.

Methods. Two groups were formed according to the type of connection between the implant and the abutment (conical and planar). Individual abutments for all systems were made using CAD-CAM technology. Using the grinding machine Metaserv 25, sagittal sections of the abutment and implant were obtained. The study and cutting the compound was carried out on a TESCAN MIRA 3 autoemission electron microscope.

Results. Using an electron microscope TESCAN MIRA 3, we obtained images of the surface of the connection of the abutment and the implant on a sagittal slice. When three-dimensional scanning of the studied samples were obtained volumetric images. Measurements of the microgap of the implant compound and abutment on the sagittal split showed that with an increase of x8000 in the first group with a conical connection, the figure varied from 0.27-3.46 microns. In the second group with a planar compound, the index varied from 6.50-9.70 microns.

Conclusions. The ratio of the abutment to the implant with conical connections showed the best results in comparison with planar connections. Using CAD-CAM technology allows you to create prostheses with good marginal fit of the connection between the implant and the abutment.
STRUCTURAL FEATURES OF THE SOFT TISSUES SURROUNDING THE IMPLANT AND FACTORS AFFECTING THE DEVELOPMENT OF INFLAMMATION IN THE REIMPLANTAL SPACE
Authors: Султанов Антон , Sultanov Anton , Первов Юрий , Pervov Yury , Яценко Анна , Yatsenko Anna , Султанова Маргарита , Sultanova Margarita , Никитан Серегей , Nikitin Sergey
Published: August 2019

Introduction. The tissues surrounding the implant, which have common features with periodontal tissues, but still possessing a certain specificity are the actual topic of the study. A considerable amount of textbooks has been written on this topic, but so far it has remained little studied.

Purpose ― to summarize all knowledge of the structural features of the tissues surrounding the implant, etiology, pathogenesis, clinical picture, differential diagnosis of the pathologies of these tissues.

Results. This review is devoted to the analysis of the modern understanding of the influence of the structural features of the soft tissues surrounding the implant and the nonspecific protection factors of the oral mucosa on the potentiation of inflammatory processes and their relationship with the biodegradation of the material. The work of scientists on the criteria for choosing an implantable material depending on the resistance to aggressive environments of the oral cavity, as well as biocompatibility with the tissues of the oral cavity. The risks of complications are considered depending on the implantable material. The etiopathogenesis of such diseases as implantation mucositis and dental periimplantitis is also considered. The clinical picture of these diseases is described, a correlation is made with the materials used for the manufacture of suprastructures. The prevention of complications arising from prosthetics on dental implants is considered.
CONDITION OF CELLULAR AND HUMORAL RELATIONSHIPS OF IMMUNITY IN CANDIDA ASSOCIATED PARODONTITIS WITH MEDIUM AND HIGH DEGREE OF QUANTITATIVE REPLACEMENT OF PARADONTAL POCKETS
Authors: Мирсаева Фания , Mirsaeva Faniya , Ханов Тимур , Hanov Timur
Published: August 2019

According to many researchers, the change in the course of chronic generalized periodontitis is associated with changes in the patient's immune status. As a result, colonization resistance decreases, the etiological role of opportunistic pathogens, fungal associations, which act synergistically with periodontal pathogenic bacteria and contribute to the development of candida-associated periodontitis, increases.

Due to the fact that this disease has little specific symptoms, relapsing course and does not respond to standard therapy, characteristic disorders in the immune system can serve as a diagnostic criterion as well as a criterion for evaluating the effectiveness of the treatment. However, to date, this issue has not been studied, taking into account the degree of quantitative contamination of periodontal pockets with fungi of the genus Candida, which was the subject of this study.

The aim is to study the state of cellular and humoral immunity during the exacerbation of candida - associated periodontitis with an average and high degree of dissemination of periodontal pockets by Candida fungi.

Methodology. A survey of cellular and humoral immunity units of 25 people with intact periodontal disease and 60 patients with exacerbation of candida-associated periodontitis, taking into account the degree of dissemination of periodontal pockets by Candida fungi. Modern and informative immunological methods of research have been used, such as T and B lymphocytes and their subpopulations, phagocytic unit, humoral factors of systemic and local immunity.

Results. An immunological study revealed that the exacerbation of candida-associated periodontitis is accompanied by changes in cellular and humoral immunity. The severity and nature of the changes depend on the degree of dissemination of periodontal pockets by Candida fungi.

Conclusions. The obtained data on changes in the indices of cellular and humoral immunity can serve as a diagnostic criterion and a criterion for evaluating the effectiveness of the treatment being carried out.
DYNAMICS OF CLINICAL AND IMMUNOLOGICAL INDICATORS IN COMPLEX TREATMENT OF CANDIDA-ASSOCIATED PERIODONTITIS
Authors: Мирсаева Фания , Mirsaeva Faniya , Ханов Тимур , Hanov Timur
Published: August 2019

Subject. The problem of complex treatment of candida-associated periodontitis is considered. The authors propose a two-component probiotic, which, due to antagonistic activity regarding periodontal pathogenic infection and fungi of the genus Candida, leads to the relief of the inflammatory process, positive dynamics and stabilization of immunological parameters.

The aim ― to evaluate the dynamics of clinical and immunological parameters in the complex treatment of candida-associated periodontitis with an average degree of quantitative seeding of periodontal pockets using a two-component probiotic.

Methodology. A clinical and laboratory examination of three groups (I, II, III) of patients with Candida-associated periodontitis with an average degree of quantitative contamination of periodontal pockets (> 3 <6 CFU / ml) was carried out. Patients I groups were prescribed the well-known complex treatment including an antimycotic drug, patients II groups included a two-component probiotic locally in the treatment complex, and patients III groups locally and per os. The state of the oral mucosa was assessed, PMA, PI, OHI - S were determined, and indicators of cellular and humoral immunity were examined.

Results. The study made it possible to establish that the inclusion of a two-component probiotic in the complex of treatment of candida-associated periodontitis with an average degree of quantitative contamination of periodontal pockets with fungi of the genus Candida contributes to the relief of the inflammatory process, an increase in phagocytosis, the metabolic activity of neutrophils, the concentration of immunoglobulins A, lysozyme levels, and a decrease in the concentration of immunoglobulins. G, positive dynamics of other indicators of immunity and their stabilization.

Conclusions. The inclusion of a two-component probiotic from two strains in the complex treatment of chronic hepatitis C associated with fungi of the genus Candida contributes to the rapid relief of the inflammatory process in periodontal tissues, positive dynamics and stabilization of cellular and humoral immunity parameters.
EVALUATION OF THE RESULTS OF COMPLEX TREATMENT OF LICHEN PLANUS OF THE ORAL MUCOSA WITH THE USE OF AUTOLOGOUS PLASMA OR HUMAN PLACENTA EXTRACT
Authors: Усманова Ирина , Usmanova Irina , Герасимова Лариса , Gerasimova Larisa , Хисматуллина Зухра , Hismatullina Zuhra , Гранот Игаль , Granot Yigal , Ахмеров Ренат , Akhmerov Renat , Абдрахманова Елена , Abdrahmanova Elena , Хуснаризанова Рауза , Khusnarizanova Rauza , Усманов Ирек , Usmanov Irek , Мудрик Ольга , Mudrik Olga
Published: August 2019

Subject. On the basis of a comprehensive dental examination, the clinical condition of the oral mucosa was assessed. With the use of laboratory research methods, the parameters of the microta state from the surface of erosion, the state of local immunity of the oral fluid, as well as anamnesis data with the assessment of somatic status, clinical blood analysis, ultrasound examination of the state of internal organs, the tactics of the complex of phased local and General therapy were studied. In clinical conditions, the analysis of minimizing pain, the nature of the epithelialization of erosive elements and regeneration of the oral mucosa. Using the analysis of laboratory methods, the pronounced antibacterial effect, increase of local immunity factors of the oral cavity, a qualitative decrease in chronic inflammation in the oral mucosa and in the body as a whole, as well as a decrease in the depressive state of the patient were evaluated. Proven and proved the efficiency of application of this complex treatment in the early and late periods.

The purpose ― is to draw the attention of practicing dentists and related specialists to the need for an effective phased scheme of diagnostic and therapeutic and preventive measures in patients with lichen planus.

Material and methods. The article is based on the description of clinical observation of a patient with erosive-ulcerative form of lichen planus.

Results. The use of the proposed complex of step-by-step local injection methods on the oral mucosa and General measures by dermatologists, therapists, gastroenterologists in the erosive and ulcerative form of lichen planus contributes to a better acceleration of the epithelialization process, regeneration, reducing the signs of chronic inflammation, qualitative improvement of the somatic status and quality of life of patients.

Summary. The inclusion in the scheme of the complex of local and General therapeutic and preventive measures of erosive-ulcerative form of lichen planus by injection of autologous plasma (AP) and human placenta hydrolysate (HRH) is a more effective method of therapy in these patients.
ANTIBIOTIC PROPHYLAXIS OF INFECTIVE ENDOCARDITIS IN DENTISTRY
Authors: Гайсина Елена , Gaysina Elena , Еловикова Татьяна , Elovicova Tat'yana , Изможерова Надежда , Izmozherova Nadezhda , Мотоусова Софья , Motousova Sof'ya
Published: August 2019

Background. Infective endocarditis is a serious disease and has the risk of disability and high mortality. This disease can be a terrible complication of both general surgical and dental invasive procedures. The problem of infective endocarditis is relevant in most countries of the world, which determine the need for targeted prevention of dental interventions. The most important pathogenetic component of this disease is transient bacteremia, which develops when the skin and mucous membrane of the oral cavity are damaged under the influence of various traumatic agents. Antibiotic prophylaxis prevents of infective endocarditis and helps to reduce the risk. Objectives ― to identify and analyze the most effective methods of antibiotic prophylaxis of IE at the dental admission. Methodology. A review of literature - publications of domestic and foreign studies using the scientific search library databases PubMed, Medline, Cochrane, Elibrary. Total found 38 publications from Russia, USA, Germany, Jordan, Saudi Arabia, Singapore, Japan and other countries. Results. The review examines studies - questioning people, clinical studies with "double glare", publication of patents, revealing the attitude to antibiotic prophylaxis of infective endocarditis at a dental reception in the world, and also analyzed the choice of drugs and their use. Conclusions. The most preferred option is to carry out antibiotic prophylaxis of the disease in people with a high risk factor, which include patients with prosthetic heart valves, congenital heart defects and patients with a history of infectious endocarditis. The drug of choice among antibacterial agents is the use of amoxicillin / clavulanic acid combination.
FREQUENCY OF THE ORBITAL WALLS FRACTURES. A RETROSPECTIVE STUDY
Authors: Абдулкеримов Тимур , Abdulkerimov Timur , Мандра Юлия , Mandra Yuliya , Герасименко Владислав , Gerasimenko Vladislav , Цех Дмитрий , Tzekh Dmitriy , Саматов Никита , Samatov Nikita , Мандра Екатерина , Mandra Ekaterina , Жегалина Наталья , Gegalina N. , Епишова Анна , Yepishova Anna
Published: August 2019

Midfacial fractures are presented by wide range of different patterns and severity. Orbital walls fractures have a special place in the structure of traumatic craniofacial injuries. Referring foreign authors, fractures of external rims and internal orbital walls are presented in more than 40 % of all bony injuries of facial skeleton. And referring Russian authors frequency of zygomaticomaxillary complex and isolated maxillary fractures presented by 12 and 8 % respectively. Furthermore complex anatomy of the orbit and proximity of the globe can occur some difficulties in diagnostics and treatment process of these patients. Today there are two main mechanisms of orbital walls fractures development – Blow-out, when fracture caused by increasing of intraorbital pressure, and Force-transmission, when force applied to external orbital rims transmits to a weaker orbital walls. Moreover in young patients Trapdoor mechanism is actual, which results in entrapment of soft tissues in the fracture line. Often there is an inferior rectus muscle entrapment and that is serious complication, when immediate surgery is required.

The article deals with issues of anatomical construction of orbit and orbital trauma epidemiology based on statistics of neurosurgical department of Central city clinical hospital № 23, Yekaterinburg, for 2017.
THE EFFICACY OF PLATELET GROWTH FACTORS (PRP) IN THE COMPLEX TREATMENT OF TMJ MALFUNCTIONS
Authors: Скоробогатько Кирилл , Skorobogatko Kirill , Петрикас Инга , Petrikas Inga , Соколова Ирина , Sokolova Irina
Published: August 2019

Background. Joint pain is often associated not only with disc displacement but also due to the level of inflammatory mediators in the synovial fluid. Injections of platelet growth factor not only expand the joint cavity, performing a purely mechanical function but also create a high concentration of growth factor in the synovial fluid, which favorably affects the cartilage tissue, joint capsule, ligamentous apparatus.

Objectives ― to study the effectiveness of platelet growth factor in the complex treatment of patients with TMJ malfunctions.

Methods. A clinical examination of two groups of patients (50 people) aged 18 to 67 years with a malfunctions of TMJ was conducted. Were used in all patients in the complex: splint therapy, myogymnastics, and manual traction drive. For the first group (25 people), concentrated growth factor in the liquid phase (PRP) was used in the treatment. For the second group (PRP) was not used. The patients were divided into two groups randomly.

Results. The results of the study were carried out according to the following criteria: pain in TMJ with a maximum opening of the mouth, protrusion, laterotruzii, sound phenomena in TMJ, myofascial pain (palpation), the presence of deviation/deflection of the lower jaw, incisional distance.

Conclusions. 1. Complex therapy, including splint therapy, myogymnastics, manual traction of the disc, the use of platelet growth factor, showed good results in the treatment of TMJ malfunctions. 2. According to all the studied criteria (pain in TMJ with a maximum opening of the mouth, protrusion, laterotruzii, sound phenomena in TMJ, myofascial pain (palpation), the presence of deviation/deflection of the lower jaw), the most effective result of treatment was obtained after 1 month.
RESULTS OF THE STUDY PEDIATRIC DENTISTS’ ACTIVITY ACCORDING TO EUROPEAN INDICATORS
Authors: Кисельникова Лариса , Kisel'nikova Larisa , Мирошкина Мария , Miroshkina Mariya , Зуева Татьяна , Zueva Tatyana
Published: August 2019

Relevance of the topic. There are a number of European indicators to monitor the dental healthcare system including C.3 (Satisfaction with service quality) and C.4 (Satisfaction with pay). High job satisfaction among the personnel leads to an increase in effective functioning of the whole organization. However, there are few data on such indicators for clinicians/dentists in Russia. Aim ― to study the level of job satisfaction of pediatric dentists, especially the satisfaction with service quality and pay. Methods and materials. The satisfaction of pediatric dentists was measured according to two European indicators (C.3 and C.4) of dental healthcare monitoring. 232 dentists (aged 22―65 years old) working for clinics of different type of ownership in Moscow and Moscow regions were interviewed. Such factors as the dentist’s age, the level of satisfaction with dental materials, instruments and equipment, the type of ownership were under study. Results. The study showed dependence of C.3 and C.4 on the factors mentioned above. 81,2 % of the dentists of private clinics were satisfied with the treatment and 72,9 % ― with the preventive dental care provided for their patients. In public clinics this proportion was 77,3 and 58,4 %. Meanwhile, the older the dentist was the less satisfaction with the dental service he had: 77,9 % of the dentists of 22―39 years old and only 50 % of those of 60 years old. The satisfaction with preventive dental care was getting lower too: from 65 to 39,6 %. 91,6 % of dentists working for the private sector were satisfied with pay compared with only 41,5 % in public clinics. This figure tended to go down with a rise of the dentist’s age. Conclusion: the dentists of 22―30 years old working for the private sector showed the highest level of job satisfaction
STUDY OF MICROSCOPIC IMPRINTS OF PURULENT WOUNDS OF THE MAXILLOFACIAL REGION IN CHILDREN WHEN USING THE OINTMENT WITH FURACILIN, LIDOCAINE AND DIBUNOLUM
Authors: Чуйкин Сергей , Chuykin Sergey , Хасанов Тимур , KXASANOV Timur , Мустафин Тагир , Mustafin Tagir , Макушева Наталья , Makusheva Natal'ya , Изосимов Артем , IZOSIMOV Artem , Викторов Сергей , Victorov Sergey , Рахмангулов Рустам , Rahmangulov Rustam
Published: August 2019

Importance ― study of microscopic imprints of the wound surface of purulent wounds in inflammatory diseases of the maxillofacial region in children.

Objectives ― cytological research of microscopic imprints of purulent wounds in inflammatory diseases of the maxillofacial region in children

Methods. The study included 60 children from 5 to 16 years old who were treated for abscesses and phlegmon of the maxillofacial area. Patients were divided independently into 2 groups. The main group included 30 children. For their treatment we used ointment with Furacilin, Lidocaine and Dibunolum. The control group included 30 patients. For their treatment used ointment Levomecol. To compare the effectiveness of the healing of purulent wounds in the main and control groups, we studied cytology of microscopic imprints of purulent wounds at 3, 7 and 10 days.

Results. A microscopic examination of the imprints of the wound surface of the control group on the 3 day revealed a predominantly inflammatory type of cytogram, on day 5, the type of cytorgamy was replaced by inflammatory-regenerative, which persisted on the 7th day of the study. Microflora was represented in small quantities. In the main group, in the study of microscopic imprints on the 3ed day, inflammatory-regenerative type of cytogram was also observed. On the 7th, the cytogram shifted to the regenerative type. Cell infiltrate was poor, containing macrophages and lymphocytes. Seeding by microorganisms was not observed.

Conclusions. Thus, based on the morphological studies of microscopic imprints of the wound surface, we recommend the use of ointment with Furacilin, Lidocaine and Dibunolum for the complex treatment of abscesses and phlegmon of the maxillofacial region. Since the ointment reduces the time of wound healing and reduces bacterial contamination of the wound.
EFFICIENT COMPUTATION OF SOBOL’ QUASI-RANDOM GENERATOR
Authors: Vesel Timotej
Published: August 2019

Purpose of the study: The quasi-Monte Carlo method is an essential tool for modeling and analyzing various complex problems in engineering, physical sciences, finance, and business. The crucial element of the method is a sequence of deterministic quasi-random values, which is often obtained by using the Sobol’ quasi-random generator. The purpose of this study is to consider the time complexity of generating the Sobol’ sequence.

Methodology: Algorithms for determining the Sobol' sequence have been studied. The algorithms have been implemented in the Python programming language.

Main Findings: It is established that this sequence can be generated in the linear time provided that generated numbers are based on 32-bit or 64-bit integers. The main result of the paper is the algorithm, which enables this time-bound.

Applications of this study: The study can be applied in engineering, physical sciences, finance, and business.

Novelty/Originality of this study: It is shown that Sobol’ sequence can be generated in linear time.
Diversidade sexual e sua proteção: antinomias e contrassensos políticos da crítica criminológica frente à necessidade de tutela penal
Authors: Divan Gabriel Antinolfi , Santos Carolinne Nhoato dos
Published: August 2019

O presente trabalho se propõe à discussão da aparente contradição causada no panorama criminológico-crítico a partir do pano de fundo do debate sobre providências legais de criminalização de condutas homofóbicas no Direito brasileiro. Utiliza a revisão bibliográfica de ideias-cânone da crítica criminológica em comparação a dados numéricos consolidados para, em um primeiro momento, buscar credenciais que legitimem o debate sobre a tutela penal da temática. Em um segundo, demonstra que existe a necessidade de um discurso crítico ser permeável a constatações empíricas e a agendas político-criminais relevantes, sem que isso o faça perder o tom crítico essencial.
Quem matou Odete Roitman? A responsabilidade do Estado sobre o entretenimento televisivo e os reflexos jurídicos da representatividade social na telenovela brasileira
Authors: Turatti Junior Marco Antonio , Bernardi Renato
Published: August 2019

Este artigo visa discutir a influência e importância jurídica das telenovelas no cenário social brasileiro. Assim, a discussão perpassa pela responsabilidade do Estado no entretenimento televisivo questionando o seu viés de atuação, uma vez que o pensamento criativo não deve ser regulado, mas sim, outras condições que garantam o Estado democrático de direito e a titularidade dos direitos humanos. Portanto, as telenovelas indicam os costumes e comportamentos sociais na televisão e demonstram aquilo que a sociedade está apta ou prefere compreender, assim, o problema de falta de representatividade se encontra na sociedade real, e não na narrativa ficcional da telenovela.
Sistema cultural de creencias religiosas. Un estado de la cuestión
Authors: Córtés Daza Johanna Emilce
Published: August 2019

En este artículo de revisión se lleva a cabo una investigación documental de carácter cualitativo, cuyo objetivo primordial es establecer un estado de la cuestión sobre la temática de los sistemas culturales de creencias religiosas. Para ello se trazó una ruta metodológica que tuvo en cuenta cuatro momentos: revisión documental; clasificación de los estudios en investigaciones académicas, libros de investigación y artículos científicos; categorización; y posterior análisis, interpretación y valoración de los enfoques teóricos y metodológicos. En los resultados se puede entrever que existe un campo investigativo prácticamente inexplorado, que debe ser valorado a través de nuevas investigaciones.
A Huntington’s disease (HD) phenocopy leads to the identification of the HD toxin as polyalanine. The relationship between repeat length and age of onset can be reframed as a rate equation and the toxic polyalanine length is found to be about 30.6.
Authors: Tarnow Eugen
Published: August 2019

Huntington’s disease (HD) is one of the most well defined “repeat diseases”, associated with a short repeated genetic sequence, CAG.First, taking into account that a phenocopy of HD has a different repeat that is associated with a different gene, I suggest that the gene is not important for HD, only the repeat sequence is important, in agreement with Lee et al (2019) who reached the same conclusion using a GWAS technique.Second, taking into account that a phenocopy of HD has a CTG repeat rather than a CAG repeat, and that the toxin should be the same for both disease types and that the third base in a codon is the least important, I suggest that the reading frame is shifted for the repeat expansions and that the A/T substitution takes place on the third base. The most likely sense and antisense reading frames are then (GCA)n and (GCT)n and (GCT)n and (GCA)n and the corresponding amino acid is polyalanine.Third, the more repeats, the earlier the HD onset (Brinkman et al, 1997; Wexler, 2004). I suggest that this relationship can be thought of as a rate equation. If the concentration is proportional to the probability of creating a polyalanine of length m in a repeat expansion of length n, the corresponding equation is borne out by the data on age of onset and repeat length and m is found to be about 30.6. This explains for the first time, at least approximately, why HD is not active unless there are at least 36 CAG repeats.If true, HD may be the first disease where frameshifting is the cause of the disease.
Modification of surface layers by high energy treatment
Authors: Vereschagin M. N. , Tselueva S. N. , Tseluev M. Yu.
Published: August 2019

Exposure to laser radiation leads to a change in the temperature field of the substance being treated. The nature of heating, which is determined by the rate of change of temperature, temperature gradients, the time to reach the temperatures of structural and phase transitions, is different depending on the properties of the material being processed and the processing conditions.

When modifying the surface layers by high-energy processing by changing the power and time of exposure to laser radiation, you can get a wide range of structural states of the treated surface areas of the material.

It is shown that the shape of TVP diagrams and cooling curves of precision alloys on the surface of a two-layer metal system after heating them with laser radiation are determined by the competition of two processes acting in opposite directions: an increase in the driving force of the crystallization process with an increase in supercooling and a decrease in the surface of atoms.

The method of surface modification by moving laser radiation allows to obtain amorphous functional layers of precision alloys on the surface of metal products.
A study of the air quality of working areas in foundries
Authors: Lasarenkov A. M.
Published: August 2019

The results of the study of air quality on workplaces of foundrymen. The results of measures of dust content and content of harmful substances in the workplace areas at foundries with different nature of production are given. It is noted that the dust content in the air of the working area of the foundry areas exceeds the maximum permissible concentrations at all workplaces, with the largest excess noted in the mass production shops. The highest exposures to dust are castings dressers, cleaners and castings technicians. The harmful substances such as carbon monoxide, nitrogen oxides, phenol, formaldehyde, etc. are also were found in the air of the working zones, the content of which is determined by the applied technological processes.
Method of providing wear-resistance of the blades of paddle mixers.
Authors: Petrishin G. V. , Bystrenkov V. M. , Odarchenko V. I.
Published: August 2019

The work is devoted to solution of the actual problem to increase the service life of blade mixers used in the foundry industry. The existing methods for ensuring wear resistance of mixing blades are described, their advantages and disadvantages are indicated. Based on the analysis of scientific publications a technical solution for applying protective coatings to the blades of the mixer using gas-thermal spraying has been proposed. The results of laboratory studies of the wear rate of gas-thermal coatings from various powder mixtures of the Ni-Cr-B-Si system under conditions of abrasive wear are presented. The results of operational tests of experimental products under conditions of corrosion and abrasive wear during the operation of a paddle mixer are given. The composition of the powder mixtur ensuring maximum wear resistance of the mixer blades was developed.
Scientific problem of metal melts. Solutions
Authors: Marukovich E. I. , Stetsenko V. Yu.
Published: August 2019

In the existing theories of liquid state of metals and alloys the basic structural element is atom. It creates a serious problem in scientific understanding of the mechanism of process of melt and properties of metal melts. For the solution of this problem it is necessary to consider that the basic structural element of liquid metals and alloys is the nanocrystal. As a result of researches it was set that metal melts are the equilibrium two-phase systems consisting on average of 97% from nanocrystals and of 3% from atoms, which form an unstructured zone.
Analisis Fator-Faktor yang Berpengaruh terhadap Return On Investment (Studi Pada Lembaga Keuangan Syariah “Kita” Desa Demangan Kecamatan Siman Ponorogo)
Authors: Maharani Shinta
Published: August 2019

Krisis ekologi yang sampai saat ini berlangsung seolah menggambarkan betapa sistem ekonomi membutuhkan pemikiran dan tindakan nyata. beberapa langkah strategis telah ditempuh baik skala besar yaitu pada tingkat Negara maupun skala kecil yaitu pada lembaga-lembaga keuangan mikro setempat. Langkah nyata yang dilakukan adalah memperkecil faktor resiko dalam investasi melalui skema “Return On Investment”. Berdasarkan hal tersebut, penelitian ini akan membahas Faktor-faktor yang mempengaruhi Return On Investment pada Lembaga Keuangan Syariah “Kita” Desa Demangan Kecamatan Siman Kabupaten Ponorogo. Penelitian ini dilakukan dengan menggunakan data primer dan data sekunder yaitu dengan pemberian kuisioner kepada para responden dan pengolahan data dari laporan keuangan. Dari populasi sebanyak 90 masyarakat yang mengajukan pinjaman, yang disetujui sebanyak 58 nasabah maka sampel ditetapkan sebanyak 58 responden pada Lembaga Keuangan Syariah ”KITA”. Analisis selanjutnya didasarkan pada laporan akuntansi keuangan yang telah dibukukan dan diolah pada Lembaga Keuangan Syariah ”KITA” dengan variabel yang digunakan Sistem Pengendalian Internal (X1) dan etika bisnis (X2).  Hasil temuan penelitian ini menyatakan bahwa sistem pengendalian internal tidak berpengaruh terhadap Return on Investment, hal ini dikarenakan sistem pengendalian internal tidak berjalan dengan  efektif, sehingga ROI tidak mampu dicapai. Sedangkan etika bisnis berpengaruh negative signifikan terhadap ROI, hal ini menunjukan bahwa semakin meningkat etika bisnis maka akan mengurangi kecenderungan kecurangan transaksi, sehingga ROI dapat tercapai. Sebaliknya semakin menurun etika bisnis maka akan meningkatkan kecenderungan kecurangan.
Treatment outcomes of Acute Appendicitis and associated factors among admitted patients with a diagnosis of Acute Abdomen in Debre Markos referral hospital, Amhara region, North West Ethiopia
Authors: Afenigus Abebe Dilie , Bayieh Agumas Mossie , Kassahun Berhanu
Published: August 2019

Introduction-

Acute abdomen is a sudden onset abdominal disease condition which often requires an immediate surgical intervention. Appendicitis is an inflammation of the vermiform appendix and is one of the most common causes of an acute abdomen in young adults. Appendicitis can cause severe periumbilical pain that radiates to the right lower quadrant, nausea, vomiting and anorexia. If left untreated, it can also cause appendiceal abscess, perforation and peritonitis.

Objective

- To assess treatment outcomes of Acute Appendicitis and associated factors among admitted patients with a diagnosis of acute abdomen in Debre Markos referral hospital from September 11/2018 to March 9/2019.

Methods and materials

- Institutional based cross sectional study was employed among 169 patients using a census sampling method. Data were collected from patient medical records, registration books and anesthesia charts available in the hospital by using checklist. Data was entered using Epi-data version 4.2 and analyzed by SPSS version 25 software. Logistic regression analysis was employed to describe the relationship between outcome and predictor variables.

Results -

Among 303 patients with a diagnosis acute abdomen, 169(55.7%) were developed acute appendicitis, of whom, 107(63.7%) were males and 62 (36.7%) were females. Among 169 patients who underwent appendectomy for treatment of acute appendicitis, 45(26.6%) of them were developed unfavorable treatment outcomes. The odds of unfavorable treatment outcomes for acute appendicitis was higher among patients who had elevated WBC count at the time of presentation [AOR=4.7; 95% CI (1.95, 11.35)] as compared with their counterparts. Similarly, those patients who had an intraoperative appendiceal abscess were more likely to have unfavorable treatment outcome for acute appendicitis [AOR= 3.8; 95% CI (1.61, 9.07)] as compared to those who didn’t have appendiceal abscess.

Conclusion and recommendation-

Nearly one-fourth of patients who underwent appendectomy for appendicitis treatment were developed unfavorable treatment outcomes. Elevated WBC count at the time of presentation and presence of intraoperative appendiceal abscess were the factors associated with unfavorable treatment outcome of acute appendicitis. Therefore, immediately evaluate patients having similar features with laboratory investigations is crucial.
Preoperative prognostic nutritional index predicts both short and long-term outcomes after liver resection for hepatocellular carcinoma.
Authors: Saito Yu , Imura Satoru , Morine Yuji , Ikemoto Tetsuya , Yamada Shinichiro , Shimada Mitsuo
Published: August 2019

Background
The aim of this study was to investigate the prognostic significance of the prognostic nutritional index (PNI) for both short and long term outcomes after liver resection for hepatocellular carcinoma (HCC).
Methods
162 (without any previous treatment) of 229 surgically treated HCC patients were retrospectively analyzed. The cut off value of the preoperative PNI was 45.0. Patients were divided into two groups, PNI low (n=76) and high (n=86) group.
Results
Among some immune parameters such as PNI, neutrophil to lymphocyte ratio (NLR) and aspartate aminotransferase (AST) to lymphocyte ratio (ALRI), PNI had most reliable parameters in terms with prediction of both short and long term outcomes. Preoperative PNI tended to correlate with low skeletal muscle mass (SMM). In short term outcomes, PNI low group were more likely to have postoperative complications. The disease-free survival rate in PNI low group was significantly worse than that in the PNI high group (20.5 vs. 48.7 %, 5 year SR, p=0.03). On multivariate analysis, Low PNI was an independent prognostic factor for disease free survival (HR 1.65, p= 0.04).
Conclusions
The preoperative PNI was the most significant prognostic factor for evaluating both short and long-term outcomes after liver resection for HCC.
The Effects of Two Exercise Modalities on Novel Cardiovascular Risk Factors in Overweight Women with Type 2 Diabetes: a Randomized Controlled Trial
Authors: Banitalebi Ebrahim , Faramarzi Mohammad , Ghahfarrokhi Majid Mardaniyan , Nasiri Samira
Published: August 2019

Background: The purpose of this study was to examine the effects of different exercise modalities (short sprint interval training (SIT) and combined aerobic + resistance training (A+R)) on novel cardiovascular risk factors (lipid accumulation product (LAP), Framingham risk score (FRS), atherogenic index of plasma (AIP), the metabolic syndrome severity scores (Mets score), visceral adipose index (VAI), body adipose index (BAI), triglyceride-glucose index (TyG index), triglyceride glucose-waist circumference (TyG-WC), triglyceride glucose-waist circumference (TyG-BMI), HOMA β-cell, and estimated glucose disposal rate (eGDR)) in overweight women with type 2 diabetes.
Methods: Fifty-two overweight females with type 2 diabetes (T2D) (aged 45-60 years, BMI > 30, hemoglobin A1c (HbA1c) ≥ 6.5 %) were assigned to either SIT (n = 17), combined training (n = 17), or control groups (n = 18). Intervention consisted of SIT or combined aerobic-strength training for 10 weeks.
Results: There were no significant changes in Mets in the SIT group after 10 weeks (p = 0.187). In addition, there were significant changes (improvements) in LAP (p < 0.001) and VAI (p = 0.002), FRS (p = 0.001), TyG index (p = 0.005), TyG-BMI (p = 0.012), TyG-WC (p < 0.001), AIP (p < 0.001), and eGDR (p = 0.001) in the combined training group after 10weeks, as compared to the baseline.
Conclusions: The results highlight that exercise training independent of the mode of training could be an effective strategy to improve some novel cardiovascular risk factors in women with type 2 diabetes.
Association between the polymorphism of MMP-1 gene with knee osteoarthritis risk: a meta-analysis
Authors: Lu Feifan , Zhang Qidong , wang weiguo , guo wanshou , liu pei
Published: August 2019

Background: The existing studies on the association between polymorphisms of Matrix metalloproteinase-1 (MMP-1) (-1607 1G/2G) (rs1799750) polymorphism and the risk of knee osteoarthritis (OA, a complex multifactorial disease and a major degenerative form of arthritis) in different populations have yielded conflicting findings.
Method: Literature search was performed in PubMed, Embase, Medline, Cochrane Library, Web of science, Google Scholar, CNKI and Wanfang database(From January 1990 to June 2019), and assessing this association by calculating odds ratios with 95% confidence intervals. Subgroup analyses stratified by ethnicity were also conducted. Statistical heterogeneity was quantitatively evaluated by X2 test with the significance set P<0.10 or I2>50%.
Result: Five case-control based studies (924 cases and 928 controls) were included. The results suggested that the MMP-1 (-1607 1G/2G) (rs1799750) gene polymorphisms were not associated with knee OA risk in all genetic models (Allele model OR =1.22, 95% CI: 0.72-1.76, p=0.615, Recessive model OR = 1.12, 95% CI: 0.70-2.15, p=0.486, and Dominant model OR = 1.14, 95%CI: 0.64-2.04, p=0.659, Figure 3-5)
Conclusions: There is no association between the polymorphism of MMP-1 (-1607 1G/2G) (rs1799750) polymorphism with the risk of knee osteoarthritis, a large number of studies may be necessary to verify this association in different populations and environmental factors.
Effect of Cognitive-Behavioral Therapy on Dietary Adherence of Patients with Ischemic Heart Disease: A Randomised Controlled Trial
Authors: Karimi Elham , Akbari Ali , Sayadi Ahmad Reza , Safarpour Hamid , Khodadadizadeh Ali
Published: August 2019

Background: It is generally accepted that diet is a key factor in increasing the risk of atherosclerosis and ischemic heart disease (IHD). Lifestyle changes can reduce the incidence of atherosclerosis. Psychological interventions are of the effective approaches to control dietary adherence. The aim of this study was to determine the effect of cognitive behavioral therapy (CBT) on the dietary adherence of IHD patients admitted to the critical care unit (CCU) of Ali ibn Abi Talib Hospital in Rafsanjan, Iran, 2018.
Methods: A randomised controlled trial was conducted through face-to-face interview on 50 patients admitted to the CCU. The samples were selected based on inclusion criteria and minimization method. The CBT was performed on the case group for three months. The researcher completed the food frequency questionnaire (FFQ) in three periods of baseline, one month and three months after the last session of intervention. Finally, the data were analyzed by SPSS version 18 software using independent t-test, paired t-test, Chi-square and Fisher tests.
Results: Overall, 50 IHD patients (25 controls, 25 cases) were enrolled in our study, consisting of 17 females (10 cases, 7 controls) and 33 males (15 cases, 18 controls). The mean age of patients participating in this study was 61 years. The mean score of dietary adherence in case and control groups at the baseline did not differ significantly (P> 0.05), but showed a significant increase after one and three months of intervention for the case group (p <0.05).
Conclusion: The results of this study showed that CBT intervention could improve dietary adherence in the IHD patients. Therefore, nurses and community health professionals can use the influence of this type of intervention on the diet modification of patients in their healthcare programs.
Trial registration: This study was registered on Iranian Registry of Clinical Trials with the registration code of IRCT20171002036498N2.
Trends in prevalence and correlates of intimate partner violence against women in Zimbabwe, 2005-2015
Authors: Mukamana Jeanette Iman'ishimwe , Machakanja Pamela , Adjei Nicholas Kofi
Published: August 2019

Background: Intimate partner violence (IPV) is a widespread problem affecting all cultures and socioeconomic groups. This study explored the trends in prevalence and risk factors associated with IPV among Zimbabwean women of reproductive age (15-49 years) from 2005-2015.
Methods: Data from the 2005/2006, 2010/2011 and 2015 Zimbabwe Demographic and Health Survey (ZDHS) on 13,409 women (survey year: 2005/2006; n=4,081), (survey year: 2010/2011; n=4,411) and (survey year: 2015; n=4,917) were analyzed. Multiple logistic regressions and hierarchical modelling techniques were applied to examine the associations between demographic characteristics, socioeconomic status, media exposure and IPV against women. We further estimated the prevalence of IPV over time.
Results: The prevalence of IPV decreased from 45.2% in 2005 to 40.9% in 2010, and then increased to 43.1% in 2015. Some of the risk factors associated with IPV were younger age, low economic status, cohabitation and rural residence. Educational attainment of women was however not significantly associated with IPV.
Conclusions: The findings indicate that women of reproductive age are at high and increasing risk of physical and emotional violence. There is thus an urgent need for an integrated policy approach to address the rise of IPV related physical and emotional violence against women in Zimbabwe.
Keywords: Intimate Partner Violence (IPV); Trends; Risk factors; Demographic and Health Surveys (DHS); Zimbabwe
Nalbuphine on postoperative gastrointestinal tract dysfunction after laparoscopic surgery for gynecological malignancies: a randomized controlled trial
Authors: Chen Jiawei , Tian Lin , Zhang Le , Hu Jianying , Huang Shaoqiang , Jiao Jing
Published: August 2019

Background

The aim of this study was to compare the effects of nalbuphine and sufentanil on the gastrointestinal (GI) tract after laparoscopic surgery for gynecological malignancies.

Methods

A total of 100 patients aged between 18-70 years with American Society of Anesthesiologists (ASA) physical status I-II who scheduled for laparoscopic radical hysterectomy under general anaesthesia were enrolled. Patients were randomized to receive either sufentanil (Group S) or nalbuphine (Group N) to receive either sufentanil (Group S) or nalbuphine (Group N) in the intraoperative and postoperative periods. The time to the first passage of flatus, the time to the first defecation, the time to the toleration of diet, the serum gastrin and the length of hospital stay were compared between the groups. Postoperative pain by visual analogue scale (VAS), the number of PCA(patient-controlled analgesia)s, postoperative nausea and vomiting, and dizziness were compared between the groups.

Results

The time to the first passage of flatus(p =0.551), the time to the first defecation(p =0.310), the time to the toleration of diet(p =0.182), the serum gastrin(p =0.397), the number of postoperative nausea(p =0.920), vomit(p =0.334) and PCA events(p =0.167) and the length of hospital stay(p =0.482) were not significantly different between the two groups. VAS scores at postoperative 6 h(p=0.008), 12 h(p =0.002) and 24 h(p =0.013) were lower in Group N than in Group S.

Conclusions

Compared with sufentanil, nalbuphine was not associated with improved postoperative GI dysfunction after laparoscopic surgery for gynecological malignancies, but it was associated with reduced postoperative pain.
The role of natural antioxidants in the prevention of periodontal diseases
Authors: Zakrzewski Mateusz , Ostrowska Anna , Magdalena Zakrzewska , Elżbieta Maciorkowska
Published: August 2019

Background: Oxidative stress is a key causative factor in chronic inflammation and plays a key role in the pathogenesis of many chronic inflammatory diseases, including periodontitis. A properly balanced diet abundant in vegetables and fruits can be a rich source of biologically active substances that inhibit reactions with oxygen and ozone. The aim of the study is to assess the influence of natural antioxidants contained in vegetables and fruits on the occurrence and progression of periodontal diseases.
Methods: The study covered a group of 368 students of the third grade (at the age of 18) of general secondary schools from the urban environment. The surveyed youth completed a survey regarding their dietary and hygienic habits. Subsequently, they participated in an oral cavity study in which the values of the plaque PL.I and gum GI index were assessed.
Results: The beneficial effect on periodontal tissues resulted from eating of fruits and vegetables and frequent consumption of apples and carrots (median GI = 0). Eating of potato chips and crisps and the use of quick-service bars intensified gingivitis (median GI = 0.1).
Conclusions: A diet intensifying oxidative stress influenced the deterioration the clinical status during the developmental age.