bluuebunny/crossref_metadata_2025 huggingface dataset:
20 ANOS DA REVISTA BIOMOTRIZ:
Authors: Krug Rodrigo de Rosso , Krug Marilia de Rosso , Krug Hugo Norberto
Published: May 2024

O objetivo deste manuscrito foi abordar a trajetória dos vinte anos da Revista Biomotriz da Universidade de Cruz Alta (UNICRUZ), enquanto um veículo de divulgação científica. Caracterizamos este manuscrito como uma pesquisa qualitativa do tipo estudo de caso, sendo utilizada à análise documental das edições publicadas da Revista Biomotriz. Concluímos que, ao longo de sua trajetória de vinte anos de existência a Revista Biomotriz buscou estabelecer-se e consolidar-se como um veículo de divulgação científica, pois é, facilmente, observável o seu crescimento quantitativo e qualitativo em suas edições publicadas. Assim sendo, a Revista Biomotriz vem ganhando espaço no cenário dos periódicos científicos, pois, com seriedade e compromisso, desde 2003 até 2023, tem sido regular em suas edições, começando a sua periodicidade como anual, passando para semestral, quadrimestral, trimestral e recentemente para fluxo contínuo. E, pela procedência dos artigos publicados em suas edições podemos afirmar que a Revista Biomotriz atingiu um patamar ‘nacional’. Nesse sentido, consideramos que os acontecimentos ao longo da trajetória de vinte anos da Revista Biomotriz da UNICRUZ mostra ‘uma história que precisa ser recontada e valorizada’.
Artificial intelligence tools for managing the behavior of economic agents at micro level
Authors: Turlakova Svitlana , Bohdan Bohdan
Published: May 2024

In modern business conditions, effective management of employee behavior is becoming a critical factor in ensuring competitive advantages and development of enterprises. AI tools, which are rapidly developing, provide new opportunities for managing the behavior of economic agents at the micro level and increasing the productivity of companies. To make the most effective use of AI in the outlined processes, there is a need to conduct research into the areas and possibilities of their application and impact on enterprise personnel. The methodology and mathematical model developed in the article, based on the use of theories of fuzzy sets, neural networks and Lefebvre reflexive control, allow to study the potential and prospects for using AI tools (on an example of SAP SuccessFactors) in managing the behavior of economic agents at the micro level, in particular in predicting the efficiency of employees at enterprise. It was concluded that the SAP SuccessFactors can evaluate the effectiveness of various personnel groups differently. This may occur due to insufficient adaptation of the models to the specifics of work and personal characteristics of employees of different productivity levels. Therefore, when using AI tools in the management of personnel behavior, it is important to consider such features and make individual settings for different groups of employee performance. This is a key aspect to avoid wrong management decisions that can affect the economic efficiency of the enterprise.
Psychological Impacts on Post-COVID-19 Patients in Raptisonari Rural Municipality, Banke District
Authors: Lal Mani Acharya
Published: May 2024

This study investigates the psychological effects experienced by patients who have recovered from COVID-19 in the Raptisonari Rural Municipality of Banke District. The primary objective is to elucidate the actual psychological impacts on these individuals. The research adopts a descriptive methodology, encompassing both quantitative and qualitative data. A sample of 80 respondents, all above the age of 20, was selected using snowball sampling. Data collection was conducted through questionnaires and informal interviews during direct visits to the respondents. The collected primary data were meticulously edited and presented in the final report, with tabulation aligned to the study's objectives. Data entry and analysis were performed using Microsoft Excel, enabling the creation of relevant tables and diagrams. The analysis revealed that 40% of respondents were aged 25-29, while only 1.25% were in the 55-59 age group. Additionally, 72.5% of the respondents belonged to the Janajati community, and all respondents were literate, with 26.25% having completed the SLC/SEE. Employment status showed that 55% of respondents were job holders. In terms of religious affiliation, 87.5% were Hindu. Regarding symptoms, 85% reported experiencing fever, cough, and tiredness, with eight clients specifically mentioning fever and four mentioning cough. Preventive measures identified included mask-wearing, as reported by 39 clients, and 35% of clients were diagnosed with COVID-19 at hospitals. The psychological impact of the COVID-19 diagnosis was significant, with 68.75% of respondents expressing fear upon diagnosis. During the isolation period, 83.75% of the respondents were in home isolation, with 50% fearing death and 45% expressing happiness upon discharge from isolation. Post-recovery, 66.25% of the respondents received congratulations from friends and family upon meeting them. This study highlights the profound psychological effects on COVID-19 recovered patients and underscores the need for targeted mental health support for this population.
Auditoría de gestión de calidad en el servicio de transporte de carga pesada para la compañía “Transroymansur” de la ciudad de Cuenca
Authors: Curillo Tama Martha Gladys
Published: May 2024

La auditoría de gestión de calidad es un procedimiento esencial para evaluar y mejorar la eficacia de los sistemas y procesos en una organización. El problema radica en la inadecuada gestión de calidad en el transporte de la compañía “Transroymansur” en Cuenca,por lo que, en este caso de estudio, el objetivo es mejorar la gestión de calidad en el servicio de transporte de carga pesada de la empresa. Desde lo metodológico se empleó el método cualitativo con enfoque analítico- sintético. Además, se aplicó el método Risicar para identificar riesgos, evaluar su probabilidad e impacto, y proponer medidas de mitigación. Se comprobó la existencia de manipulación y entregas inadecuadas de la carga con posibilidades de daños a la mercancía y pérdida de clientes, estos entre otras deficiencias en el sistema, para lo se propone estrategias de mejora en el ámbito administrativo con lo cual se optimiza cualitativamente el proceso administrativo de la empresa.Palabras Clave: calidad, compañía, transporte, Risicar, riesgo
Abstract
Quality management audit is an essential process for evaluating and improving the effectiveness of systems and processes in an organization. The problem lies in the inadequate quality mana- gement of the “Transroymansur” company’s transport in Cuenca, so the aim is to improve the quality management of the Company’s heavy-duty transport service. From the methodological point of view, the qualitative method with an analytical-synthetic approach was used. In addition, the RISK method was applied to identify risks, evaluate their probability and impact, and propose mitigation measures. There was evidence of impro- per handling and delivery of the cargo with the potential for damage to the goods and loss of customers. Poor communication both with clients and internally could trigger dissatisfaction, loss of business, and lack of alignment between employees for which different improvement strate-gies were proposed
Keywords: quality, transport, company, Risicar, risk.
Pengaruh Permainan Puzzle Terhadap Perkembangan Motorik Halus Anak Di KB Penerus Bangsa Desa Tanjung Kepayang
Authors: Ana Herliana , Putri Yecha Febrieanitha , Fahmi Fahmi
Published: May 2024

Penelitian ini berjudul Pengaruh Permainan Puzzle terhadap Perkembangan Motorik Halus Anak di KB Penerus Bangsa Desa Tanjung Kepayang. Adapun yang menjadi permasalahan yaitu suatu gambaran bahwa peserta didik pada kemampuan mengenal huruf belum berkembang dengan maksimal. Tujuan penelitian ini yaitu untuk mengetahui adakah pengaruh permainan puzzle terhadap perkembangan motorik halus anak di KB Penerus Bangsa Desa Tanjung Kepayang. Jenis penelitian ini adalah Pre-experimental dengan one group pretest-posttest design (satu kelompok subjek). Jumlah sampel berjumlah 13 anak di KB Penerus Bangsa Desa Tanjung Kepayang. Teknik pengumpulan data dalam penelitian menggunakan observasi awal sebelum diberi perlakuan dengan media permainan puzzle, observasi digunakan untuk mengumpulkan data pada saat treatment, tes berbentuk skor yang dilakukan untuk mengetahui hasil setelah diberi perlakuan dan dokumentasi berupa foto. Teknik analisis data yang digunakan dalam penelitian ini menggunakan uji normalitas, uji homogenitas dan uji hipotesis. Hasil hipotesis nilai signifikansi (2-tailed) = 0.000 0.05 menunjukkan adanya perbedaan yang signifikan antara variabel awal dengan variabel akhir, ini menunjukkan hipotesis Ha diterima dan Ho ditolak artinya permainan puzzle berpengaruh signifikan terhadap perkembangan motorik halus anak di KB Penerus Bangsa Desa Tanjung Kepayang.
PENGARUH APLIKASI CANVA TERHADAP MEMBACA PERMULAAN ANAK USIA 4-5 TAHUN DI RA PERWANIDA 1 PALEMBANG
Authors: Afrima Opi , Oktamarina Lidia , Soraya Nyayu
Published: May 2024

Rendahnya membaca anak mengenal huruf, menyebutkan, mengeja, mengenal bunyi menjadi 1 tujuan. Peneliti mengangkat penelitian yang berjudul Pengaruh Aplikasi Canva Terhadap Membaca Permulaan Anak Usia 4-5 Tahun Di RA Perwanida 1 Palembang. Tujuan dari penelitian ini yaitu untuk mengetahui apakah ada pengaruh dari aplikasi Canva terhadap membaca permulaan anak usia dini. Jenis dari penelitian ini yaitu Pre-Eksperimental dengan menggunakan desain One Group Pretest-Posttest. Teknik pengumpulan data menggunakan dokumentasi dan tes. Teknik analisis pada penelitian ini menggunakan uji normalitas, uji homogenitas, dan uji hipotesis. Setelah dilakukan tes awal (pretest) dan test akhir (posttest), selanjutnya peneliti menganalisis semua hasil penelitian, dari penelitian ini dapat disimpulkan terdapat pengaruh yang signifikan antara aplikasi Canva dalam meningkatkan membaca permulaan anak diperoleh thitung = 3,076 sedangkan ttabel = 2.16. Karena thitung ttabel (3,076 2,16), maka dapat disimpulkan Ho ditolak dan Ha diterima. Maka dapat disimpulkan bahwa terdapat pengaruh aplikasi Canva terhadap membaca permulaan anak usia 4-5 tahun di RA Perwanida 1 Palembang.
Game Digital Tebak Gambar Berbasis Kearifan Lokal Budaya Lampung
Authors: Aisy Nurjihan Rohadatul , Sartika Indah Dwi , Murtopo Ali , Wahyuni Desvi
Published: May 2024

Melihat dari revolusi pendidikan yang mulai berkembang dan modern banyak muncul pembelajaran-pembelajaran yang dibuat melalui teknologi, seperti film edukasi, cerita bergambar edukasi dan permainan atau game berbasis Android. Penelitian ini dilakukan untuk membuat sebuah produk game berbasis digital tebak gambar usia 5-6 tahun tentang kearifan lokal budaya Lampung di TK Pembina Way Kanan Lampung yang valid, praktis dan efektif. Untuk mengetahui metode penelitian yang dipakai yaitu metode penelitian research and development. Adapun tahapan pengembangannya analisis (analysis), pengembangan (development), desain (design), implementasi (implementation) dan evaluasi (evaluasi). Teknik pengumpulan data dilakukan menggunakan observasi, angket dan dokumentasi. Analisis data dilakukan dengan teknik penilaian kevalidan, kepraktisan serta keefektifan oleh validator materi, media dan bahasa. Serta praktisi dilakukan oleh 2 guru yang ada di TK Pembina Way Kanan Lampung. Hasil kevalidan validator materi 87,5%, media 92,5% dan bahasa 85%. Serta hasil kepraktisan 100% dan 96,6% dan keefektifan 93,24% dan 85,18%.
Peran Lingkungan Dalam Pengembangan Bahasa AUD
Authors: Haryati Haryati
Published: May 2024

Peran lingkungan merupakan sebuah wadah dalam proses perkembangan keterampilan bahasa dan bicara anak, karena lingkungan bagian dari interaksi anak dalam proses perkembangannya. Tujuan penelitian ini adalah untuk mendeskripsikan peran lingkungan dalam pengembangan bahasa anak. Metode dalam penelitian ini menggunakan metode kualitatif dengan pendekatan literatur atau studi kepustakaan. Sumber yang diambil dari berbagai macam literatur baik jurnal, artikel maupun penelitian terdahulu serta sumber internet lainnya. Hasil dalam penelitian ini menunjukan hasil bahwa peran lingkungan dalam pengembangan bahasa dapat melatih anak dengan mengenalkan kata-kata sapaan yang baik dan benar dalam berkomunikasi, mengajak anak dalam mengenal benda-benda yang ada di sekitarnya, menerapkan pola asuh demokratis, pengembangan mengintegrasikan kemampuan bahasa dalam kehidupan sehari-hari, pengembangan kemampuan mengekspresikan diri sendiri.
Introducing Artificial Intelligence and Machine Learning in K12 Education to Foster 21st Century Skills: From Theory to Practice
Authors: Mazzucato Annaleda , Larghi Silvia
Published: May 2024

This paper focuses on the interdisciplinary and collaborative approach underpinning the European funded project Edu4AI “Artificial Intelligence and Machine Learning to Foster 21st Century Skills in Secondary Education”. The methodology has been conceived to enhance the practice of teaching from course design to content delivery, drawing inspiration from social constructivist theories, and inquiry project based learning instructional methods, combining elements from the maker movement and the educational robotics platforms. The final output of this process has been a particle handbook that comprises ready to use project toolkits, suitable to guide the seamless integration of Artificial Intelligence (AI) and Machine Learning (ML) in K12 school curricula, including non-scientific ones. The paper introduces the theoretical frameworks inspiring the toolkits that have been created cooperatively with the teachers’ community and piloted in the school real contexts for validation. One of the toolkit projects is also presented in the article, outlining the corresponding learning goals in terms of both hard and transversal life skills acquired, in order to ensure correspondence with students' learning outcomes evaluation. Following the presentation of the results from questionnaires collected during the project, the article concludes with some key recommendations for practitioners willing to replicate the initiative.
REBRANDING UMKM CATERING MELALUI DESAIN PACKAGING DAN PROMOSI MEDIA SOSIAL
Authors: Hidayat Azamul , Febriana Poppy , Rochmaniah Ainur , Bisri Muhammad Hasan
Published: May 2024

The problem faced in the Mbok Ndut Catering and Bu Sri Catering catering businesses is that there is no label on the packaging and does not have media as a promotion, so it requires rebranding the packaging design in the form of labels and promotion of the business on social media. The purpose of this community service activity is to provide solutions to the problems being faced. The method used is to provide training in the form of tutorials on how to manage Instagram accounts and how to operate the Google Maps application. The results of this community service are to help the two MSME players create a logo design, create an official Instagram account, create a content design for Instagram posts, create a packaging design in the form of labels, add the location of the Catering business address through the Google Maps Application, train or teach the two MSME players, manage Instagram by posting the menu that we provide with interesting content, and how to operate the Google Maps Application. Thus, in the future it can make it easier for the two MSME players to introduce their business to the wider community.
Imaging Insights into the Diverse Manifestations of Psoriatic Arthritis
Authors:   , Kleinrensink Nienke Josephine
Published: May 2024

Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease, with diverse clinical manifestations including psoriasis (Pso) of the skin or nails, in combination with peripheral arthritis, dactylitis (swelling of an entire digit), enthesitis (inflammation at the site where tendons/ligaments attach to the bony surface) or axial disease. PsA is part of the group of rheumatic conditions we refer to as 'spondylarthritis' (SpA), which also includes ankylosing spondylitis, reactive arthritis and arthritis in the context of inflammatory bowel disease, among others. With the use of different imaging techniques such as x-rays, magnetic resonance imaging (MRI) and, in experimental settings, positron emission tomography/computed tomography (PET/CT) we can capture the diverse (sub)clinical disease manifestations of these patients, to advance our understanding of disease pathogenesis, monitor disease activity or to predict treatment response.
Although many further steps are needed, the works presented in this thesis show that subclinical disease is common at the enthesis of Pso and SpA patients and that the inflammatory reaction in PsA may also involve non-musculoskeletal organs such as the arterial wall. With the TOFA predict study, study-protocol described in this thesis, we aim to deliver evidence-based imaging predictors of treatment response and learn more on the relevance of subclinical findings on MRI and PET/CT.
Influence of blowing ratio on double-wall cooling characteristics under the condition of high-temperature flue gas
Authors: Yi Baichuan , Xiong Yan , Liu Zhigang , Liu Yan , Wei Xiaopo
Published: May 2024

Double-wall cooling has been extensively investigated due to its exceptional cooling performance. However, most previous studies on the cooling characteristics of double-wall geometry have been conducted under non-reacting conditions, neglecting the influence of high-temperature flue gas radiation. In this paper, an experiment investigation was carried out to evaluate the impact of blowing ratio M and coolant-to-gas temperature ratio on the cooling characteristics of effusion/impingement cooling at reacting flow conditions. The experiments were performed at atmospheric pressure with flame temperatures of 1,800 and 1,900 K respectively. Flue gas temperature was measured by S-type thermocouples, while an infrared camera and N-type thermocouples were employed for the gas-side wall surface temperature distribution measurements. The results demonstrate that the laterally averaged cooling effectiveness of the effusion/impingement cooling system increases with the increase of M. However, beyond a blowing ratio of 5.1, further increments in M do not significantly affect the cooling effectiveness. Moreover, it is observed that the laterally averaged cooling effectiveness gradually improves along the flow direction but at a reduced rate. Additionally, no significant changes in cooling effectiveness are observed after X/D > 50. Furthermore, when considering a blowing ratio of 4, higher coolant temperatures result in higher cooling effectiveness compared to lower coolant temperatures.
The Renewed Mainstay of the Russian Authoritarian Regime
Authors: Kurbangaleeva Ekaterina
Published: May 2024

In 2023, the Russian economy, despite huge military spending, declining exports, and tightening sanctions, showed growth of 3.6%. The researcher based on in-depth interviews and analysis of official data from the reports of the Federal Tax Service of Russia and the Federal State Statistics Service for 2022-2023 examines how and to what extent the revenues/incomes of regions, industries, and population groups have changed. As of the end of 2023, the beneficiaries of the Ukrainian war included numerous groups of low-income people, mainly employed in manufacturing industry and living in underdeveloped regions of Russia. Under these conditions, the author can assume that the level of support for the Putin regime among these groups of people is likely to increase and strengthen. Research is ongoing, so conclusions regarding the demographic characteristics of beneficiary groups and predictions of the following support for the Putin regime have yet to be proven.
Note for the Prime Gaps
Authors: Vega Frank
Published: May 2024

A prime gap is the difference between two successive prime numbers. The nth prime gap, denoted $g_{n}$ is the difference between the (n + 1)st and the nth prime numbers, i.e. $g_{n}=p_{n+1}-p_{n}$. There isn't a verified solution to Andrica's conjecture yet. The conjecture itself deals with the difference between the square roots of consecutive prime numbers. While mathematicians have showed it true for a vast number of primes, a general solution remains elusive. We consider the inequality $\frac{\theta(p_{n+1})}{\theta(p_{n})} \geq \sqrt {\frac{p_{n+1}}{p_{n}}}$ for two successive prime numbers $p_{n}$ and $p_{n+1}$, where $\theta(x)$ is the Chebyshev function. In this note, under the assumption that the inequality $\frac{\theta(p_{n+1})}{\theta(p_{n})} \geq \sqrt {\frac{p_{n+1}}{p_{n}}}$ holds for all $n \geq 1.3002 \cdot 10^{16}$, we prove that the Andrica's conjecture is true. Since $\frac{\theta(p_{n+1})}{\theta(p_{n})} \geq \sqrt {\frac{p_{n+1}}{p_{n}}}$ holds indeed for large enough prime number $p_{n}$, then we show that the statement of the Andrica's conjecture can always be true for all primes greater than some threshold.
Annual Proceedings of the 2023 H-Net Teaching Conference
Authors: Zukas Lorna L.
Published: May 2024

H-Net Past President Lorna Zukas introduces the volume and its importance to educators.
The study demands and resources scale: psychometric properties, longitudinal invariance, and criterion validity
Authors: van Zyl Llewellyn E. , Shankland Rebecca , Klibert Jeff , Verger Nicolas B. , Rothmann Sebastiaan , Cho Vincent , Feng Katherine , See-To Eric W. K. , Roll Lara C. , Ghosh Anindita , van der Meij Leander , Arijs Diane , Cole Matthew L. , Stavros Jacqueline M. , Hulshof Inge L. , Di Blasi Zelda , De Beer Leon T.
Published: May 2024

The Study Demands and Resources Scale (SDRS) has shown promise as a valid and reliable measure for measuring students’ specific study demands and -resources. However, there is no evidence as to its psychometric properties outside of the original context in which it was developed. This study aimed to assess the psychometric properties of the SDRS in a cross-national student population through examining its longitudinal factorial validity, internal consistency, and temporal invariance as well as criterion validity through its association with study engagement and task performance over time. Results showed that a Bifactor Exploratory Structural Equation Model (ESEM) with one general factor (overall study characteristics) and five specific factors (workload, growth opportunities, lecturer support, peer support, information availability) fitted the data, showed strong measurement invariance over time, and was reliable at different time points. The study further established criterion validity for the overall study characteristics factor through its concurrent and predictive associations with study engagement and task performance. However, the specific factors’ concurrent and predictive capacity could only partially be established when controlling for the general study characteristics factor. These findings suggest that study characteristics should be measured as a dynamic interaction between study demands and resources, rather than a hierarchical model.
Integrated multi-omics and artificial intelligence to explore new neutrophils clusters and potential biomarkers in sepsis with experimental validation
Authors: Xu Peng , Tao Zuo , Zhang Cheng
Published: May 2024

Background

Sepsis, causing serious organ and tissue damage and even death, has not been fully elucidated. Therefore, understanding the key mechanisms underlying sepsis-associated immune responses would lead to more potential therapeutic strategies.

Methods

Single-cell RNA data of 4 sepsis patients and 2 healthy controls in the GSE167363 data set were studied. The pseudotemporal trajectory analyzed neutrophil clusters under sepsis. Using the hdWGCNA method, key gene modules of neutrophils were explored. Multiple machine learning methods were used to screen and validate hub genes for neutrophils. SCENIC was then used to explore transcription factors regulating hub genes. Finally, quantitative reverse transcription-polymerase chain reaction was to validate mRNA expression of hub genes in peripheral blood neutrophils of two mice sepsis models.

Results

We discovered two novel neutrophil subtypes with a significant increase under sepsis. These two neutrophil subtypes were enriched in the late state during neutrophils differentiation. The hdWGCNA analysis of neutrophils unveiled that 3 distinct modules (Turquoise, brown, and blue modules) were closely correlated with two neutrophil subtypes. 8 machine learning methods revealed 8 hub genes with high accuracy and robustness (ALPL, ACTB, CD177, GAPDH, SLC25A37, S100A8, S100A9, and STXBP2). The SCENIC analysis revealed that APLP, CD177, GAPDH, S100A9, and STXBP2 were significant associated with various transcriptional factors. Finally, ALPL, CD177, S100A8, S100A9, and STXBP2 significantly up regulated in peripheral blood neutrophils of CLP and LPS-induced sepsis mice models.

Conclusions

Our research discovered new clusters of neutrophils in sepsis. These five hub genes provide novel biomarkers targeting neutrophils for the treatment of sepsis.
The relationships between emerging adults self-efficacy and motivation levels and physical activity: a cross-sectional study based on the self-determination theory
Authors: Tao Yuexian , Xu Tao , Wang Xin , Liu Chengyi , Wu Yinyin , Liu Mingyue , Xiao Ting , Qiu Xinze
Published: May 2024

Objectives

The study aims to examine the associations between exercise self-efficacy, motivation, physical activity, and body composition among emerging adults.

Design

Cross-sectional.

Methods

A convenience sample of 147 emerging adults participated in the Releasing Weight (RELEW) project. The InBody720 analyzer was used to measure body composition, and the International Physical Activity Questionnaire-Short, the Shortened Physical Activity Self-Efficacy Scale, and the Treatment Self-Regulation Questionnaire were used to measure self-reported physical activity, self-efficacy, and motivation. Structural Equation Modeling was used to exam the complex relationships among multiple variables. in this study. The Partial least squares structural equation modeling analysis with bootstrapping in Smart PLS 3 was employed to explore the path coefficients and t-values for the relationships that were thought to exist. Significance was determined using a threshold of p < 0.05.

Results

The mean age of 147 participants was 18.5 ± 1.87, of whom 51.7% were female, recruited for this study. Exercise self-efficacy has a significant positive correlation with exercise motivation (r = 0.220, p = 0.008) and physical activity (r = 0.279, p < 0.001). Exercise motivation does not demonstrate significant associations with physical activity (r = 0.094, p = 0.298). Utilizing SEM, the model explained 9.2% of exercise self-efficacy, 11.8% of physical activity, and 68.3% of body composition variance. Mediation analysis revealed that exercise self-efficacy partially mediated the relationship between exercise motivation and physical activity (β = 0.106, t = 2.538, p < 0.05), and physical activity partially mediated the relationship between exercise self-efficacy and body composition (β = −0.296, t = 4.280, p < 0.001).

Conclusion

This study sheds light on the complex relationships among motivation, self-efficacy, physical activity and body composition during emerging adulthood. Our results highlight the mediating role of self-efficacy and its impact on physical activity behaviors, offering valuable insights for targeted interventions and policy development to improve health outcomes in this demographic.
Psychological intervention in women victims of childhood sexual abuse: a randomized controlled clinical trial comparing EMDR psychotherapy and trauma-focused cognitive behavioral therapy
Authors: Molero-Zafra Milagros , Fernández-García Olga , Mitjans-Lafont María Teresa , Pérez-Marín Marián , Hernández-Jiménez María Jesús
Published: May 2024

Introduction

Childhood sexual abuse persists as a painful societal reality, necessitating responses from institutions and healthcare professionals to prevent and address its severe long-term consequences in victims. This study implements an intervention comprising two psychotherapeutic approaches recommended by the WHO and international clinical guidelines for addressing short-, medium-, and long-term posttraumatic symptomatology: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and Eye Movement Desensitization and Reprocessing (EMDR). Both approaches are adapted from group formats for implementation in small online groups via Zoom.

Methods

The impact of both therapeutic approaches on trauma improvement was assessed in a sample of 19 women who were victims of childhood sexual abuse through a Randomized Clinical Trial comparing EMDR Psychotherapy and Trauma-Focused Cognitive Behavioral Therapy after a baseline period. Intra and inter comparison were made using statistics appropriate to the sample.

Results

Both therapeutic approaches significantly reduced symptomatology across various evaluated variables, suggesting their efficacy in improving the quality of life for these individuals. Following CBT-FT treatment, patients exhibited enhanced emotional regulation, reduced reexperiencing, and avoidance. The EMDR group, utilizing the G-TEP group protocol, significantly improved dissociation, along with other crucial clinical variables and the perception of quality of life.

Discussion

Although the limitations of this study must be taken into account due to the size of the sample and the lack of long-term follow-up, the results align with existing scientific literature, underscoring the benefits of trauma-focused psychological treatments. The online group format appears promising for enhancing the accessibility of psychological treatment for these women. Furthermore, the differential outcomes of each treatment support recent research advocating for the inclusion of both approaches for individuals with trauma-related symptomatology.

Ethics and dissemination

The study has been approved by the Ethics Committee of the Valencian International University (VIU) (Valencia, Spain) (Ref. CEID2021_07). The results will be submitted for publication in peer-reviewed journals and disseminated to the scientific community.

Clinical trial registration

https://clinicaltrials.gov/ct2/show/NCT04813224, identifier NCT04813224.
Intervention effects of telenursing based on M-O-A model in empty-nest older adult individuals with chronic diseases: a randomized controlled trial
Authors: Yuan Yuan , Hou Ping , Wang Sican , Kitayama Akio , Yanagihara Kiyoko , Liang Jingyan
Published: May 2024

Aim

This study aims to verify the effectiveness of M-O-A telenursing intervention model in improving the health status and quality of life of the empty-nest older adult individuals with chronic diseases by a randomized comparative trial.

Methods

M-O-A telenursing intervention model was constructed based on the needs of the participants. The control group (N = 39) received routine nursing, the experimental group (N = 39) received M-O-A telenursing intervention in addition to routine nursing. After 12 weeks of intervention, the intervention effects of being a participant in the two groups were evaluated. SPSS 26.0 was used for data analysis.

Results

After 12 weeks of intervention, for the experimental group, each dimension of quality of life based on EQ-5D-3L became better, especially for “pain/discomfort,” “anxiety/depression,” “HRQoL” and “EQ-VAS” (all p < 0.05) and each dimension of quality of life based on SF-36 became better too, especially for “GH,” “BP,” “RE,” “MH,” “VT,” “SF,” “PCS,” “MCS,” “SF-36” (all p < 0.05). In addition, there was a statistical downward trend in blood pressure, blood glucose, weight, BMI, fat rate, nap duration, number of nocturnal awakenings, light sleep rate and a statistical upward trend in water rate, basal metabolic rate, nighttime sleep duration, deep sleep rate, rapid eye movement sleep rate, especially at the end of intervention (all p < 0.05). While for the control group, there was no statistical improvement in all these aspects.

Conclusion

The M-O-A telenursing model could effectively regulate quality of life and health condition of the empty-nest older adult individuals with chronic diseases, making it worthy of further promotion and application.
Location-dependent flight cost difference from the lunar surface to an orbital fuel depot and its influence on in situ resource utilisation location selection
Authors: Steinert Sven J. , Zabel Paul , Quantius Dominik
Published: May 2024

Given the increasing relevance of lunar activities, the location selection for in situ resource utilisation (ISRU) facilities is necessary for identifying the most suitable configuration during mission planning. To gather information about the dominant location dependencies, a scenario is established wherein an ISRU product is exported to an orbital depot and its mass costs are used for classification. In the selected scenario, oxygen is produced in an ilmenite reduction plant and subsequently exported to the lunar gateway via an oxygen–hydrogen fuelled launcher operated in a round-trip to refuel oxygen at the lunar surface and hydrogen at the lunar gateway. This showed that the transport cost variations could be avoided entirely or have a recessive influence on the mission’s total costs over an extended period of time, such as 20 years. The identification of the top-10 most optimal locations for various resolutions was altered only slightly upon consideration of flight costs as compared to considering only the ISRU factors; this indicates the insignificance of flight cost dependencies for the analysed case.
The effect of oral zonisamide treatment on serum phenobarbital concentrations in epileptic dogs
Authors: Mahon Elizabeth , Marsh Oliver , Uriarte Ane , Stabile Fabio
Published: May 2024

Zonisamide is used in dogs for the treatment of epileptic seizures. It is predominantly metabolised by CYP450 hepatic enzymes. When used concurrently with phenobarbital (PB), zonisamide clearance is increased and its elimination half-life decreases. However, the effect that zonisamide may have on serum PB concentrations in dogs has not been previously described. Eight dogs diagnosed with idiopathic epilepsy and two dogs with structural epilepsy commenced zonisamide at 8.0 mg/kg/12 h [7.4–10 mg/kg/12 h] following an increase in the frequency of epileptic seizures. Nine dogs were receiving PB every 12 h (4.2 mg/kg/12 h [3.8–6 mg/kg/12 h]), and one dog was receiving PB every 8 h (6 mg/kg/8 h). Following the addition of zonisamide and despite no increase in PB dosage, an increase in phenobarbital serum PB concentration was observed in 9 out of 10 dogs in subsequent measurements. In five dogs, phenobarbital serum concentrations were raised to concentrations higher than the reported hepatotoxic concentrations (trough>35 mg/L). This required a reduction in daily doses of PB. This case series suggests that zonisamide affects the metabolism of PB and causes an increase in PB serum concentrations over time.
The difference in radiographic findings in the distal limbs of working Lipizzan horses, used for dressage or driving
Authors: Zalig Valentina , Vengust Modest , Blagus Rok , Berner Dagmar , Sandow Cole , Hanna Ashley , Miklavcic Mitja
Published: May 2024

Introduction

Lameness originating from the distal limb is common in sport horses and can vary depending on the dynamics of movement and the surface, with differences in shoeing exacerbating this variability. Driving horses work primarily on hard surfaces (pavement), whereas dressage horses work primarily on soft surfaces (riding arenas with sand). Driving horses are traditionally shod with small fixed studs made of hard metal, which are attached to the horseshoe at 4 points, while dressage horses are shod with a simple horseshoe. We investigated the hypothesis that there is a difference in the pathological radiographic findings of the distal limbs between driving and dressage horses. The variability in the stable management and training program was minimized by including horses from the same farm.

Methods

Twenty horses in a driving training program and 20 horses in a dressage program were included in the study. Radiographs of the both front feet were obtained and quantitatively evaluated for radiographic changes by three surgery/diagnostic imaging specialists. Interrater reliability was measured, and multivariate analysis was performed to compare differences in pathological radiographic findings of the distal limbs between the two groups.

Results

Kendal’s concordance coefficient indicated an agreement among raters (Kw ≠ 0) for all observations. Radiographic signs of degenerative joint disease of the distal interphalangeal joint were more common in the group of driving horses compared to dressage horses.

Conclusion

Our hypothesis was confirmed, as there were significant pathological differences between groups in distal articular margin of middle phalanx, joint space narrowing, and irregular joint surface of the middle phalanx.
Multi-omics unveils tryptophan metabolic pathway as a key pathway influencing residual feed intake in Duroc swine
Authors: Wang Shujie , Chen Dong , Ji Xiang , Shen Qi , Yu Yang , Wu Pingxian , Tang Guoqing
Published: May 2024

The genetic trait of residual feed intake (RFI) holds considerable importance in the swine industry. Recent research indicates that the gut microbiota of pigs plays a pivotal role in the manifestation of the RFI trait. Nevertheless, the metabolic pathways involved in the functioning of these microorganisms remain elusive. Thus, based on the ranking of the RFI trait in Duroc pigs, the present study selected the top 10 and bottom 10 pigs as the experimental subjects. The distribution and metabolite differences of cecal microbiota were analyzed using 16S rRNA gene sequencing and liquid chromatography–tandem mass spectrometry (LC–MS/MS) techniques. The low RFI cecal group was named LRC, and the high RFI cecal group was named HRC. The results indicate that the LRC group had lower RFI, feed conversion ratio (FCR), average daily feed intake (ADFI) (p < 0.001), and thinner backfat (p < 0.05) compared with the HRC group. We simultaneously recorded the foraging behavior as well, the LRC group had a significant increase in total time spent at the feeder per day (TPD) (p < 0.05) and a significant increase in average feed intake per mins (AFI) and the number of visits to the feeder per day (NVD) compared to the HRC group (p < 0.001). Clostridium_XVIII, Bulleidia, and Intestinimonas were significantly enriched in the LRC group (p < 0.01), while Sutterella, Fusobacterium, and Bacteroides were significantly increased in the HRC group (p < 0.01). In the metabolome, we detected 390 (248 metabolites up and 142 down in the LRC compared with HRC), and 200 (97 metabolites up and 103 down in the LRC compared with HRC) differential metabolites in positive and negative ionization modes. The comprehensive analysis found that in the LRC group, Escherichia and Eubacterium in the gut may increase serotonin content, respectively. Bacteroides may deplete serotonin. We suggest that the RFI may be partly achieved through tryptophan metabolism in gut microbes. In individuals with low RFI, gut microbes may enhance feed efficiency by enhancing host synthesis and metabolism of tryptophan-related metabolites.
No detectable differences in Nef-mediated downregulation of HLA-I and CD4 molecules among HIV-1 group M lineages circulating in Cameroon, where the pandemic originated
Authors: Sonela Nelson , Mann Jaclyn , Godwe Celestin , Goni Oumarou H. , Tchakoute Mérime , Nkoue Nathalie , de Oliveira Tulio , Brockman Mark A. , Brumme Zabrina L. , Ndung’u Thumbi , Tongo Marcel
Published: May 2024

HIV-1 group M (HIV-1M) lineages downregulate HLA-I and CD4 expression via their Nef proteins. We hypothesized that these Nef functions may be partially responsible for the differences in prevalence of viruses from different lineages that co-circulate within an epidemic. Here, we characterized these two Nef activities in HIV-1M isolates from Cameroon, where multiple variants have been circulating since the pandemic’s origin. Single HIV-1 Nef clones from 234 HIV-1-ART naïve individuals living in remote villages and two cosmopolitan cities of Cameroon, sampled between 2000 and 2013, were isolated from plasma HIV RNA and analyzed for their capacity to downregulate HLA-I and CD4 molecules. We found that, despite a large degree of within- and inter- lineage variation, the ability of Nef to downregulate HLA-I was similar across these different viruses. Moreover, Nef-mediated CD4 downregulation activity was also well conserved across the different lineages found in Cameroon. In addition, we observed a trend towards higher HLA-I downregulation activity of viruses circulating in the cosmopolitan cities versus the remote villages, whereas the CD4 downregulation activities were similar across the two settings. Furthermore, we noted a significant decline of HLA-I downregulation activity from 2000 to 2013, providing additional evidence supporting the attenuation of the global HIV-1M population over time. Finally, we identified 18 amino acids associated with differential HLA-I downregulation and 13 amino acids associated with differential CD4 downregulation within the dominant CRF02_AG lineage. Our lack of observation of HIV lineage-related differences in Nef-mediated HLA-I and CD4 downregulation function suggests that these activities do not substantively influence the prevalence of different HIV-1M lineages in Cameroon.
The Related Role of Anxiety and Parental Resilience on the Aggressive Tendencies of Preschool Children during the COVID-19 Pandemic
Authors: Durgut Şakrucu Evrim , Demircioğlu Haktan
Published: May 2024

In this study, we aimed to determine the related role of anxiety and parental resilience on the aggressive tendencies of preschool children during the COVID-19 pandemic. The study sample comprised a total of 293 parents with children aged 4–6 years. Relationships between Preschool Anxiety Scale, Aggression Orientation Scale, and Brief Resilience Scale total and subscale scores were evaluated using Pearson and Spearman correlation analysis. The results of this study show that there is a positive relationship between children’s aggression tendencies and anxiety levels. We observed weak to moderate correlations between parents’ resilience scores and the children’s aggression and anxiety scores. Although linear regression analysis indicated no significant effect of parental resilience on children’s aggressive tendencies, anxiety levels may be related. In addition, study results showed that the physical aggression tendencies of children differed according to their age and the number of children in the family, albeit at a low level. Further studies are needed to identify factors associated with aggression in preschool children.
A High-Voltage Pulse Modulator Composed of SiC MOSFETs/IGBTs in a Hybrid Connecting State
Authors: Kang Zhuang , Xie Xiaofeng , Liu Yang , Chen Daibing , Yuan Haitao , Zhao Liu , Zhao Hai , Yang Chengliang , Zheng Guiqiang
Published: May 2024

In order to solve problems such as a slow switching speed, a high switching power, a loss of pure IGBT modulators, and the weak withstanding load short-circuit ability of pure SiC MOSFET modulators used for vacuum loads, this paper proposes a new scheme for high-voltage pulse modulators based on SiC MOSFET/IGBT hybrid connecting circuits. It has a low power loss like the pure SiC MOSFET modulator and a strong withstanding load short-circuit ability like the pure IGBT modulator. Firstly, the principle circuit of the hybrid connecting modulator are discussed and chosen. And the basic working processes of the hybrid parallel-series modulator is described in detail. Secondly, three key points in this new scheme are analyzed and designed as follows: the static and dynamic voltage sharing; the actualizing of the ZVS process for IGBTs; the improvement of short-circuit protection for SiC MOSFETs. A modulator consisting of 16-stage 1200 V-SiC MOSFETs and 1200 V-IGBTs in hybrid parallel-series states is tested. Based on the sample circuit, the working data, such as high-voltage pulse waveforms of 10 kV/2 KHz/10 μs, static and dynamic voltage sharing, the driving control sequence, the U/I sequence of the IGBT, the short-circuit protection waveform, and the calculation, are obtained and discussed.
Letare Taxandria: Regionalism and Hagiographic Interactions between Sint-Oedenrode, ’s-Hertogenbosch, and Liège in the Medieval Cult and Liturgy of St Oda
Authors: Saucier Catherine
Published: May 2024

“Rejoice, Texandria, for Oda!” Thus begins the series of chants and readings commemorating the virgin St Oda, patron of the village that took her name—Sint-Oedenrode—in the late medieval liturgy of the town of ’s-Hertogenbosch. Overt praise for the surrounding region, Texandria, extending across the northern limits of the duchy of Brabant and diocese of Liège, is a recurring theme in the liturgy inspired by the saint’s legend. Yet how did Oda, of Scottish origin, become so closely associated with this remote region? And what was the significance of her liturgical veneration in ’s-Hertogenbosch, to which Sint-Oedenrode was enfranchised? Exemplifying interactions between central and secondary places within a specific region, this study argues for the relevance of the historical approach to urban–rural dynamics in medieval hagiography and its related liturgy. Recognition that smaller towns and villages played important roles in regional networks prompts more focused attention to regional priorities in the legends and liturgies of local saints. That Oda’s cult is attested by a diversity of extant documentary evidence—historical, hagiographic, and liturgical, including newly discovered liturgical readings—facilitates interpretation of her veneration in ’s-Hertogenbosch and of the intertextual connections between her legend and those of other saints, notably Lambert, associated with the duchy and diocese. As suggested by this example, regionalism merits greater scrutiny as an integral component of civic religion.
Human Sustainability
Authors: Hartmann Silja , Funk Maria
Published: May 2024

Eine zentrale Frage der menschlichen Nachhaltigkeit am Arbeitsplatz ist, wie Arbeit bewältigt werden und ein hohes Leistungsniveau sichergestellt werden kann und gleichzeitig diejenigen, die die Arbeit leisten, nicht ihre Gesundheit oder ihr Wohlbefinden gefährden, sondern langfristig gestutzt werden. Organisationen stehen in der Verantwortung, Mechanismen, Strukturen und Prozesse zu etablieren, die menschliche Nachhaltigkeit am Arbeitsplatz fordern. Das Phänomen der psychologischen Resilienz ist ein Beispiel dafür, wie Menschen am Arbeitsplatz wachsen können, während das Konzept von Allyship beschreibt, wie durch soziale Unterstützung am Arbeitsplatz Diskriminierung entgegengewirkt werden kann.