bluuebunny/crossref_metadata_2025 huggingface dataset:
International Journal of Role-playing 2: Full Issue
Authors: Montola Markus , Arjoranta Jonne , White William J. , Balzer Myriel , Curran Noirin , Harviainen J. Tuomas
Published: May 2023

International Journal of Role-Playing Issue 2: Full Issue
Table of Contents
Editorial -- Markus MontolaThe International Journal of Role-Playing is a response to a growing need for a place where the varied and wonderful fields of role-playing research and development, covering academia, the industry and the arts, can exchange knowledge and research, form networks and communicate.
Jonne Arjoranta -- Defining Role-Playing Games as Language-Games
This paper looks at one of the latest attempts to define role-playing games, and shows some potential problems with it. As an answer to these problems another definition is proposed, consisting of a game world, participants, shared narrative power and interaction.
William J. White -- Playing House in a World of Night: Discursive Trajectories of Masculinity in a Tabletop Role-Playing Game
Using excerpts from the transcript of a tabletop role-playing game session, this study examines how male players enact ideas about masculinity.
Myriel Balzer -- Immersion as a Prerequisite of the Didactical Potential of Role-Playing
The article deals with the relation of immersion and the didactical potential of role-playing. It fathoms the extent to which role-playing games without a didactical goal still have didactical potential, as well as the extent to which this potential is being exploited.
Noirin Curran -- Stereotypes and Individual Differences in Role-playing Games
Investigating earlier research into the individual differences in those who play role-playing games, this article provides a comprehensive review of research in the areas of demographics, interests, personality and identity as they pertain to gamers.
J. Tuomas Harviainen -- Sadomasochist Role-Playing as Live-Action Role-Playing: A Trait-Descriptive Analysis
This article describes sadomasochist role-playing which is physically performed by its participants, and compares that to live-action role-playing.
Stereotypes and Individual Differences in Role-playing Games
Authors: Curran Noiran
Published: May 2023

Because of the endurance of stereotypes about role-playing gamers, much research has been carried out which provides evidence to contradict the stereotype’s prevailing misconceptions. This paper aims to investigate this existing research into the individual differences in those who play role-playing games and provide a comprehensive review of research in the areas of demographics, interests, personality and identity as they pertain to gamers. The goal will be to investigate the extent to which the common perception of game-players stands up under investigation. The paper will also attempt to refute some of the more extreme and outrageous claims which have been made in relation to role-playing games – particularly those which involve crime,violence, murders, suicides and Satanism. The article will also examine child’s play and role-playing games in order to illustrate the importance of this style of imaginary play for identity development for both children and adults.

The stereotypical image of role-playing gamers depicts them as anti-social male teenagers who are largely more interested in technology than in their own personal appearance, believing that they are highly intelligent and imaginative, passionate about topics which are uninteresting to their peers, and consequently persecuted by some of these peers. Through an examination of the research carried out in this area, the emerging image of a gamer is in fact that of an individual who does not necessarily fit into the stereotypical demographic of being a young male, and who is actively involved in developing his or her own personality and identity through participation in the games and also within the social networks that are often framed by these games.
Educational Larp in the Middle School Classroom - A Mixed Method Case Study
Authors: Bowman Sarah Lynne , Standiford Andhe
Published: May 2023

This mixed method case study examines the effectiveness of an educational role-playing (edu-larp) intervention into the science curriculum of a charter school in Los Angeles that serves an economically disadvantaged population. Utilizing psychometric surveys and semi-structured interviews, the investigators gathered data from middle school students evaluating their development along five dimensions of learning before and after the semester-long program: intrinsic motivation, perceived competence, school engagement, team work, and leadership. The study also gathered qualitative data from the 23 students in this convenient sample group regarding their overall experiences with the edu-larp method.When paired with traditional pedagogy, out of these five dimensions of student development, the investigators found that the edu-larp intervention helped increase overall intrinsic motivation and interest/enjoyment of science in the quantitative data. The qualitative and quantitative findings merged to reveal improvement in perceived competence in science. In interviews, students demonstrated a strong belief that larp aided in the development of all five dimensions and expressed universal interest in learning through edu-larp in the future. Overall, the data suggested that adding the edu-larp component to the existing science curriculum impacted the experience of students by increasing interest, engagement, and perceived competence in science through game play and role enactment.
The Effects of Using Academic Role-Playing in a Teacher Education Service-Learning Course
Authors: Crow Mary Lynn , Nelson Larry P.
Published: May 2023

Academic role-playing is one of the more effective active-learning instructional strategies currently being used at the American university level in the preparation of future educators. This mixed methods study is an investigation of the use of role-play in an undergraduate university course designed to prepare students to become public school coaches and physical education teachers. The five original vignettes that were role-played were specifically written to prepare the students to successfully handle situations they might reasonably encounter in their future work. The role-play model used in the research was originally created by the Shaftels in the 1960s, but several creative variations devised by the current investigators were added to that model for this study causing it to be an adapted version. Data collected included questionnaire responses from two different questionnaires, information from a focus group, and observations by the two investigators. Investigators concluded that the students not only exhibited skill in the techniques used to resolve the issues in the vignettes, but that students gained confidence the more they participated in the role-plays which occurred over a 4-week period. The students themselves reported that learning from one’s peers, trying out their ideas in a safe environment, being forced to plan an intended outcome in advance, and hearing feedback from others were their most valued experiences. They also overwhelmingly reported preferring role-play to the more traditional university lecture method.
Review: Playing at the World
Authors: Loponen Mika , Särkijärvi Jukka
Published: May 2023

Jon Peterson’s Playing at the World is an ambitious history of the early developments of Dungeons & Dragons, arguably the first and most popular role-playing game.
Caleidoscopio de saberes
Authors: Pérez Alan , Garcia Alejandra , Vargas Alethia , Gómez Alma , Méndez Ana , Barrera Andrea , Martínez Antar , Valdivia Benjamín , Hernández Carmen , Caloca Cecilia , Rodríguez Claudia , Estrada Dafne , Nelson Dana , Villagómez Daniela , Jervaise Eric , Sosa Eurídice , Tapia Evangelina , Medrano Gabriel , Herón Gustavo , Espinosa Hilda , Pérez Hugo , Montaño Hugo , Bernaola Igor , Martínez Irene , Herrera Jesahe , Zepeda Jesús , Torres José , Guzmán Juan , Haidar Julieta , Cuevas Julio , Ibarra Koldovike , Naranjo Krishna , Márquez Lía , Márquez Liliana , Valladares Liliana , Greathouse Louise , Pérez Lucía , Lazos Luz , Orenday Magaly , Rábago Marcela , Pedroza María , Gutiérrez María , Suárez María , García Miguel , Abarca Mireya , Pérez Myriam , Molina Nancy , Rivera Osiris , Maríñez Pablo , Parra Rodrigo , Salas Salvador , Fuentes Sergio , García Simón , Martínez Tamara , Visbal Tatiana , Eltit Yvaín
Published: May 2023

Este libro constituye un esfuerzo colectivo por mostrar un panorama de los nuevos escenarios en los que se vive la interculturalidad, el patrimonio cultural y los estudios socioculturales, a partir de diferentes aproximaciones a las raíces de los significados sociales, que orientan el actuar diario ante problemáticas cotidianas y entramados sociales, que ayudan o dificultan las formas de relacionarnos, reconociendo la diversidad social y cultural que favorece el diálogo de saberes que enriquece el patrimonio cultural. De igual manera, presenta algunas experiencias educativas, desde distintos escenarios, orientadas al reconocimiento de la interculturalidad, para favorecer el respeto a todas las manifestaciones de la diversidad cultural, social y de género. A través de las páginas de esta obra se manifiestan las bondades y potencialidades de las aproximaciones interdisciplinarias y transdisciplinarias para el análisis de la interculturalidad, el patrimonio y la vida cotidiana. La pluralidad temática, teórica y metodológica de las contribuciones que integran cada uno de los capítulos del libro corresponde con la confluencia de los abordajes característicos de los estudios de género, el folclor, la lingüística, la literatura, la comunicación, la pedagogía y la filosofía, además de algunas reflexiones que beben de la perspectiva decolonial y los estudios socioculturales.
Hubungan Islamic Self Esteem dengan Social Loafing pada Mahasiswa Program Studi Pendidikan Agama Islam
Authors: Maulan Fitri , Ru’iya Sutipyo
Published: May 2023

This research started with students from the Ahmad Dahlan University Islamic Religious Education study program class of 2019 who did social loafing. The purpose of this study was to determine the level of self-esteem and social loafing in students of the Islamic Religious Education study program class of 2019 at Ahmad Dahlan University and also to find out whether there is a correlation between self- esteem and social loafing. This study uses a type of correlational quantitative research. The research population was students of the Ahmad Dahlan University Islamic Religious Education study program class of 2019 with a total of 383 students with a sample of 196 students. The number of samples obtained through the Slovin formula and sampling using probability sampling technique with simple random sampling. The independent variable in this study is self-esteem, while the dependent variable is social loafing. To measure the scale of the two variables, 24 statement items were used for each variable. Then the reliability value for the self-esteem scale is 0.855 and the social loafing scale is 0.910. In analyzing the correlation between the two variables, this study used the Pearson product moment correlation technique. The results showed that there was a negative and significant correlatin between self-esteem and social loafing in students of the Ahmad Dahlan University Islamic Religious Education Study Program class of 2019 with a correlation coefficient of -0.662 and a significance value of 0.000, namely <0.05. As for the description of the level of student self-esteem, it is included in the medium category with a percentage value of 69% and the level of social loafing is included in the medium category with a percentage value of 67%.
Penyimpangan Prinsip Kesantunan Berbahasa di Kalangan Remaja Suku Dayak Kanayan Dialek Ahe Kabupaten Bengkayang Kalimantan Barat
Authors: Dwi Syafutri Husni , Arnisyah Siti , Novita Rian , Ester Ester , Ernawati Ernawati
Published: May 2023

This study aims to describe the deviation of politeness among adolescents in Kanayan Dayak Ahe. The method used in this research is a qualitative method to reveal the types of deviations. The focus of this research is Language Politeness among Adolescents of the Dayak Kanayan Tribe of Ahe Dialect using sociopragmatic studies. The results of this study indicate that there are types of deviation from the principle of language politeness used in the interaction of the youth of the Kanayan ethnic group. Ahe dialect consists of: (1) wisdom maxim, (1) maxim of generosity, (3) maxim of charity, (4) maxim of humility, (5) maxim of compatibility, and (6) maxim of sympathy. The politeness scale of a speech is held as a measure or indicator of the politeness of a speech act in both formal and informal situations
Etika Komunikasi Dalam Ruang Media Massa: Analisis Framing Pemberitaan LGBT di Media Lokal Jambi
Authors: Muchamad Taufani Eka , Novealdi Herri , Widodo Andeka
Published: May 2023

The phenomenon of the presence of LGBT groups in Indonesia has been discussed for a long time. Marked by the emergence of the first openly gay organization, namely Lambda Indonesia on March 1, 1982, since then until now LGBT groups have tried to show their existence in the public space. This is done as an effort so that their existence can be accepted and recognized in society. The objective of this research is to describe how online media in Jambi Province positions LGBT news. And knowing the framing and application of ethics in reporting on LGBT. The research was conducted using qualitative methods with library research by exploring theories and their relationships or with the influence between each variable sourced from books, journals, and others, both offline in the library, and obtained online from the internet. During the period June-September 2022, Tribunjambi.com reported a lot about the Erayani case. There are 103 stories published by this media by taking various reporting perspectives. Jambi Independent in total there are 12 stories that have been published on their media portal. Jambi Update Online Media contains 12 news stories. Metrojambi.com contains 18 news published by Metrojambi.com until September 1, 2022. Meanwhile, Jambina.com only contains one news. The report was published on June 21, 2022. In framing the news on the LGBT case regarding the Erayani case, both online media Tribunjambi.com, Jambi Independent, Metrojambi.com, Jambi Update, and Jambina.com are not much different.
Penerapan Model Pembelajaran Discovery Learning untuk Meningkatkan Kemampuan Mengindentifikasi Teks Laporan Hasil Observasi Pada Peserta Didik Kelas X SMAN 1 Muara Sugihan
Authors: Hernawati Linda , Missriani Missriani , Fitriani Yessi
Published: May 2023

This study aims to apply the discovery learning learning model in improving the ability to identify the text of the observation report for students of SMAN 1 Muara Sugihan. To achieve this goal, the classroom action research was conducted with three cycles. Based on the results of the study, it can be concluded that the application of the discovery learning model can improve the ability to identify the text of the observation report of class XI students of SMAN 1 Muara Sugihan. In cycle I, the action of the first cycle has not been achieved regarding the observation aspect, then in the second cycle, the observed aspects have increased but cannot be said to have reached the KKM, so the researcher takes action in cycle III. In cycle III, all aspects observed experienced an increase from the previous two cycles. The average increase from the results of observations in the learning process cycle I and cycle II increased to thirtysix students or around 51.42%. In this cycle there was an increase to 27.14%. In cycle III there was an increase from the previous two cycles, the proportion achieved was 73.86% (seventythree point eighty six percent) and there were sixty seven students who achieved scores above the KKM. So, the increase achieved was 43.58% (fortythree point five eight percent).
Manajemen Supervisi Akademik Kepala Madrasah di MTS Amal Bakti Kota Prabumulih
Authors: Wulandari Dwi , Harapan Edi , Mahasir Mahasir
Published: May 2023

This study aims to describe the process of managing the academic supervision of madrasah principals carried out at MTs Amal Bakti, Prabumulih City. The method used in this research is a descriptive qualitative approach. Data and data sources in this study are divided into two, namely primary data and secondary data. Primary data includes data taken through interviews, documentation and observations made to informants. While secondary data includes data that has been processed. determining the informants in this study through a purvosive sampling technique by mapping the informants based on the analysis of positions and years of service at MTs Amal Bakti. The results of the study illustrate that the implementation of academic supervision at MTs Amal Bakti applies management functions which include: planning, organizing, acting, and controlling. After academic supervision, the results showed that there was an improvement in teachers in preparing learning tools, determining learning methods and media and with the results of academic supervision the madrasah head could provide follow-up in the form of guidance, training and training to teachers, especially teachers who had many problems at school. in the learning process.
Options for modifying UK alcohol and tobacco tax: A rapid scoping review of the evidence over the period 1997–2018
Authors: Hatchard Jenny , Buykx Penny , Brennan Alan , Gillespie Duncan
Published: May 2023

Background: Increased taxation is recognised worldwide as one of the most effective interventions for decreasing tobacco and harmful alcohol use, with many variations of policy options available.  This rapid scoping review was part of a NIHR-funded project (‘SYNTAX’ 16/105/26) and was undertaken during 2018 to inform interviews to be conducted with UK public health stakeholders with expertise in alcohol and tobacco pricing policy.

Methods: Objectives: To synthesise evidence and debates on current and potential alcohol and tobacco taxation options for the UK, and report on the underlying objectives, evidence of effects and mediating factors. Eligibility criteria: Peer-reviewed and grey literature; published 1997–2018; English language; UK-focused; include taxation interventions for alcohol, tobacco, or both. Sources of evidence: PubMed, Scopus, Cochrane Library, Google, stakeholder and colleague recommendations.

Charting methods: Excel spreadsheet structured using PICO framework, recording source characteristics and content.

Results: Ninety-one sources qualified for inclusion: 49 alcohol, 36 tobacco, 6 both. Analysis identified four policy themes: changes to excise duty within existing tax structures, structural reforms, industry measures, and hypothecation of tax revenue for public benefits. For alcohol, policy options focused on raising the price of cheap, high-strength alcohol. For tobacco, policy options focused on raising the price of all tobacco products, especially the cheapest products, which are hand-rolling tobacco. For alcohol and tobacco, there were options such as levies that take money from the industries to help reduce the societal costs of their products. Due to the perceived social and economic importance of alcohol in contrast to tobacco, policy options also discussed supporting pubs and small breweries.

Conclusions: This review has identified a set of tax policy options for tobacco and alcohol, their objectives, evidence of effects and related mediating factors. The differences between alcohol and tobacco tax policy options and debates suggest an opportunity for cross-substance policy learning.
TBE in Austria
Authors: Stiasny Karin , Aberle Judith H.
Published: May 2023

Since 1972, the documentation of human cases of tick-borne encephalitis (TBE) in Austria has been performed by the Center for Virology, Medical University of Vienna, which acts as the National Reference Laboratory for TBE and other flavivirus infections. Only hospitalized patients with a recent tick-borne encephalitis virus (TBEV) infection confirmed by laboratory diagnosis are counted as cases. Confirmation is usually based on immunoglobulin (Ig) serology (namely enzyme-linked immunosorbent assay [ELISA] for IgM and IgG). However, this confirmation may be supplemented by virus neutralization and polymerase chain reaction (PCR) analyses if needed.
TBE in Italy
Authors: Tagliapietra Valentina , Riccardo Flavia , Del Manso Martina , Rezza Giovanni
Published: May 2023

Italy is considered a low-incidence country for tick-borne encephalitis (TBE) in Europe. Areas at higher risk for TBE in Italy are geographically clustered in the forested and mountainous regions and provinces in the north east part of the country, as suggested by TBE case series published over the last decade. A national enhanced surveillance system for TBE has been established since 2017. Before this, information on the occurrence of TBE cases at the national level in Italy was lacking. Both incidence rates and the geographical distribution of the disease were mostly inferred from endemic areas where surveillance was already in place, ad hoc studies and international literature.
TBE in Kyrgyzstan
Authors: Erber Wilhelm
Published: May 2023

There is very little information and there are only a few publications on TBE in Kyrgyzstan. A survey by Atkinson references the following: In humans and birds low seropositivity has been demonstrated as early as 1973. In 1978 the TBEV was isolated from ticks, and twelve human cases were reported between 1976–1981.
TBE in Belarus
Authors: Kniazeva Volha , Erber Wilhelm , Vuković-Janković Tamara
Published: May 2023

Belarus is a landlocked country of eastern Europe with a population of 9.4 million, of which 78.4% reside in urban areas bordered by Lithuania and Latvia to the north west, by Russia to the north and east, by Ukraine to the south, and by Poland to the west. The country of Belarus is divided into six administrative districts (Brest, Gomel, Grodno, Minsk, Mogilev, Vitebsk regions) each centered around a major city (Minsk). Much of the country consists of ﬂat lowlands separated by low-level topped hills and uplands; the highest point is Dzyarzhynskaya Hill, being only 1135 feet (346 meters) above sea level. Over half of the surface area of Belarus lies below 660 feet (200 meters), and about 40% of the country is forested. The most common tick species in Belarus are Ixodes ricinus and Dermacentor reticulatus.
TBE in Moldova
Authors: Erber Wilhelm , Vuković-Janković Tamara
Published: May 2023

Although there are no reliable data on the number of tick-borne encephalitis (TBE) cases or the percentage of infected ticks, based on the geography and the presence of TBE virus (TBEV) in all neighboring countries, it must be assumed that TBEV is present somewhere in Moldova.
TBE in Romania
Authors: Chitimia-Dobler Lidia , Hristea Adriana , Erber Wilhelm , Vuković-Janković Tamara
Published: May 2023

Based on an epidemiological survey, human TBEV neuroinfections may have an endemic emergent course, and natural foci are in full territorial expansion. Identified risk areas are Tulcea district, Transylvania, at the base of the Carpathian Mountains and the Transylvanian Alps. TBE has been a notifiable disease since 1996. Surveillance of TBE is not done at the country level, only regionally in some counties (northern/central/western part, close to Hungary). The passive surveillance system was implemented in 2008. However, there is no regular screening and the relative risk of contracting this disease is unknown. In 1999, an outbreak of TBE in humans was recorded with a total of at least 38 human cases. The probable cause of the outbreak was goat milk and raw goat milk products. Subsequent studies to detect TBEV in ticks in the affected regions resulted in a non -specified number of TBEV isolates, which were described as belonging to the European subtype of TBEV. A publication of the neighboring Republic of Moldova described the existence of the Far-eastern subtype of TBEV just at the border to Romania.
TBE in United Kingdom
Authors: Holding Maya , Schmitt Heinz-Josef , Ellsbury Gillian
Published: May 2023

Until 2019, TBE was considered only to be an imported disease to the United Kingdom. In that year, evidence became available that the TBEV is likely circulating in the country and a first “probable case” of TBE originating in the UK was reported. In addition to TBEV, louping ill virus (LIV), a member of the TBEV-serocomplex, is also endemic in parts of the UK. Reports of clinical disease caused by LIV in livestock are mainly from Scotland, parts of North and South West England and Wales.
TBE in Croatia
Authors: Erber Wilhelm , Vuković-Janković Tamara
Published: May 2023

Even though tick-borne encephalitis (TBE) has been a notifiable disease in Croatia since 2007, there are no or only limited data available on the occurring tick species in the endemic areas, on the prevalence of TBE virus (TBEV) in ticks, its distribution in Croatia, and its genetic characteristics. Reporting of human cases also is very scarce. The Central European subtype of virus (TBEV-EU) appears to be present in Croatia.
Chapter 12c: Risk Map For TBEV
Authors: Dobler Gerhard , Erber Wilhelm , Bröker Michael , Chitimia-Dobler Lidia , Schmitt Heinz-Josef
Published: May 2023

TBE Risk Map.
Chapter 3: Transmission/Natural cycle
Authors: Chitimia-Dobler Lidia , Mackenstedt Ute , Kahl Olaf
Published: May 2023

The natural cycle of the TBE virus is dependent on vector ticks and reservoir hosts. There are differing transmission cycles in varying environments, from cold northern coniferous forests to temperate central European forests. Within a natural transmission cycle, there are different ways of transmission: tick-to-tick (transovarial, sexual), host-to-tick (viremic), and also tick-to-tick and host-to-host. The complexity of natural transmission cycles is inadequately explored and poorly understood.
Chapter 8: TBE in animals
Authors: Pfeffer Martin , Schmuck Hannah M. , Leschnik Michael
Published: May 2023

TBE can cause clinical symptomatic disease in dogs and horses
Diagnosis of TBEV infection in animals is similar to diagnosis in humans
Animals can be used as sentinels for human exposure
H.A.C. Beets-Damsté, 1871-1954
Authors: Gera Judit
Published: May 2023

‘Zouden deze grote intelligentie, deze levendige belangstelling in mens en wereld niet meer en schoner vruchten hebben gedragen in een tijd, die deze gaven in een vrouw meer wist te waarderen?’ Zo karakteriseert de broer van Helbertine Anna Cornelia Beets-Damsté, Onno, de deugden van zijn zus in het levensbericht dat hij schreef voor het Jaarboek van de Maatschappij der Nederlandsche Letterkunde te Leiden, 1955-1956. Hiermee geeft hij duidelijk te kennen dat Helbertines mentaliteit in de periode die haar gegeven was naar zijn mening niet op waarde werd geschat. Enerzijds was zij zo ouderwets dat ze misschien eerder thuishoorde in het victoriaanse tijdperk, anderzijds waren haar deugden en sociale betrokkenheid in een later tijdperk evenzeer markant en uniek geweest. Ook haar vertaaloeuvre verdient lof. Zo vertaalde ze circa acht werken uit het Zweeds en een veertigtal uit het Hongaars, waaronder werk van Kálmán Mikszáth en Géza Gárdonyi. Wie was deze intelligente, open vrouw die volgens haar broer in haar eigen tijd niet genoeg gewaardeerd was?
A praediabetes és diabetes szûrése
Authors: Rosta László
Published: May 2023

A 2-es típusú diabetes komplex anyagcsere-betegség, amely a micro- és macrovascularis szövôdmények megelôzése és kezelése céljából szinte folyamatos, mul ti disz - ciplináris megközelítésû egészségügyi ellátást igényel. A folyamat lassítása csak költ - séghatékony, célzott szûréssel, a gondozásba vétel és a kezelés idôben való elkezdésével valósítható meg. A FINDRISC szû - rést egyértelmû költséghatékonysága és a diabetes korai felfedezésének, valamint idô - beni kezelési lehetôségének a betegek életminôségére, munkaképességére gyakorolt pozitív hatása miatt lenne hasznos az alapellátásban minél szélesebb körben, esetlegesen akár többletfinanszírozással alkalmazni.
A 2-es típusú cukorbetegség inzulinkezelése a háziorvosi gyakorlatban
Authors: Oláh Ilona , Vörös Krisztián
Published: May 2023

Az inzulinkezelés az 1-es típusú cukorbetegségben nélkülözhetetlen az életben maradáshoz. A 2-es típusú cukorbetegséggel élôk egy részénél a „nem inzulin szerek” mellett, a jó anyagcserehelyzet biztosítása érdekében lehet szükség inzulin alkalmazására. Az inzulinkezelés a gyors és erélyes hatás mellett lehetséges mellékhatásokkal is rendelkezik, ezért alkalmazásának sarokköve a megfelelô indikáció. Közleményünkben áttekintjük azokat a szempontokat, amelyek mentén jó döntést hozhatunk az inzulinterápia bevezetésére vonatkozóan. Összefoglaljuk az inzulinkezelés alkalmazására rendelkezésünkre álló számos inzulinkészítményt és inzulinalkalmazási rendszert. Elemezzük az analóg inzulinkészítmények elônyeit a human inzulinokkal szemben. Bemutatjuk azokat a betegre és a terápiás lehetôségekre vonatkozó jellemzôket, amelyek figyelembevétele elengedhetetlen a terápiás terv készítésekor. A kezelésre vonatkozó döntést a beteggel együttesen kell meghoznunk. Az inzulinkezelés bevezetésének idôszakában különösen nagy szükség van a beteg önmenedzselô képességének (DSMES) kialakítására, fejlesztésére. A háziorvosoknak nagy szerepük van az inzulinkezelésre szoruló betegek kiválasztásában és szakellátóhelyre irányításában, majd az inzulinkezelt betegek támogatásában. Számukra átfogó, friss információt igyekszünk közvetíteni, valamint rávilágítunk arra, hogyan tudja segíteni a háziorvos cukorbetegei ellátását, illetve mik a diabetológiai szakellátóhellyel való együtt - mûködés legfontosabb elemei.
INTERNATIONAL MIGRATION, GLOBAL INEQUALITIES AND ITS IMPLICATION ON ANTI-POVERTY POLICY
Authors: Anggraini Wike , . Arwanto
Published: May 2023

Abstract

The purpose of this article is gaining an understanding on whether international migration contribute positively or negatively to global inequalities. Furthermore, it aims to analyze the implication of migration to anti-poverty policy within a country. Researchers use a literature review method to draw a conclusion on the relationship between international migration and global inequalities. Accordingly, international migration could affect both positive and negative on global inequality. It could reduce poverty through remittances, increasing wage level in the sender country, and brain exchange. On the other hand, it also has result on asymmetric development and an increase of dependence on destination countries. Furthermore, immigration affected anti-poverty practices and programs as well. According to a number of studies, policy must take into account the effects of migration on poverty and development. Social exclusion is a problem for anti-poverty initiatives. However, a dilemma arose during the policy-making process: who will be accountable for the difficulties of migrants, particularly illegal migrants? The host country or the local government?

 

Keywords: migrants, international migration, inequalities, poverty, policy
System of financial equalization in Ukraine under modern challenges: main problems and directions for their solution
Authors:   SI “Institute of regional research named after M. I. Dolishniy of the NAS of Ukraine, STORONIANSKA Iryna , BENOVSKA Liliya ,   SI “Institute of regional research named after M. I. Dolishniy of the NAS of Ukraine, MEDYNSKA Tetyana ,   Lviv University of Trade and Economics
Published: May 2023

Introduction. The introduction of a new equalization system in Ukraine is faced with problems related to the inconsistency of the redistribution of resources and powers between state, regional and local authorities, the instability and inconsistency of legislative innovations, the unreasonableness of the calculation of the tax capacity index, etc. Problem Statement. The existence of significant economic and financial imbalances in the development of the territories of Ukraine necessitates the search for an optimal model of financial equalization. This question is actualized in the conditions of modern challenges. Purpose. To identify the main problems of the financial equalization system in Ukraine and to find ways of their solving.. Methods. In the research process such methods as structural-logical, comparative analysis, systematic approach, historical and statistical and others were used. Results. It was found that the domestic model of financial equalization should be identified as a combination of three components: vertical equalization through split taxes; horizontal equalization of the fiscal capacity of budgets and equalization by expenditures through a set of targeted transfers.The article identifies the main problems of financial equalization, namely: the calculation of the index of the tax capacity of territorial communities, which is based only on income from one tax (personal income tax), does not ensure a fair distribution; the inclusion of personal income tax at the place of registration of business entities helps to strengthen the differentiation between the center and the periphery; the predominance of targeted transfers reduces the independence of local self-government bodies in decision-making; poor use of expenditure equalization tools has led to significant imbalances in the ability of communities to provide public services. Conclusions. The solution to the mentioned problems is proposed by: implementing the mechanism of personal income tax crediting to local budgets by place of residence, and not by place of work of individual payers; calculation of the tax capacity index, taking into account the entire volume of tax revenues to the general fund of local budgets; the growth of the share of untargeted transfers in the structure of the system of financial equalization of territories in Ukraine and others.
Institutional support for the formation of digital infrastructure in the conditions of European integration processes: a case for Ukraine
Authors:   SESE “The Academy of Financial Management”, ZATONATSKIY Dmytro
Published: May 2023

Introduction. The European integration course actualizes the need for more dynamic development of all processes aimed at the formation of digital infrastructure in Ukraine. Strengthening existing and forming new elements is one of the priority directions of the state policy of countries in the context of the transition to the digital economy. Problem Statement. The use of an institutional approach will make it possible to explain the current state and predict further ways of development of the digital infrastructure of Ukraine. Purpose.To assess the state and prospects of institutional support for the formation of Ukraine's digital infrastructure in the context of European integration processes and to develop recommendations to facilitate investment in it. Methods. The methods of dialectical logic, sociological, theoretical generalization and comparison, abstract-logical, scientific generalization are applied. Given the multifaceted nature of the research subject, the methodological basis is formed by such methods as graphic, structural-functional, and expert evaluations. Results. It was established that the institutional support for the formation of digital infrastructure is the actions of the authorities aimed at the creation of state and non-state institutions, which must provide legal, organizational and economic foundations for changing models of public management and administration, the functioning of business entities through the dominant use of technologies, products and processes using computing, telecommunications and network capabilities of electronic interaction, data exchange, signals, etc. and operate on a digital rather than analog basis. The legal basis for the formation of digital infrastructure is analyzed. The organizational basis includes the presence of relevant institutions in the state both public and private, which are part of the digital infrastructure and ensure its functioning (the state in the form of state authorities (state institutions), business entities and non-profit organizations (private institutions) ). Conclusions. Since the economic base is based on own funds and involved investments, it is proposed: at the legislative level to adopt a strategy for the development of digital infrastructure taking into account European integration processes; attract investments and invest in knowledge and human capital; initiate the creation of crowdfunding platforms, which will facilitate the search for investors for the implementation of startups in the field of digital infrastructure. As part of the development of digital infrastructure, it is proposed to shift the main attention to the development of network and information infrastructure.
Assessment of sustainability and development prospects of the energy system of Ukraine
Authors:   National University of Life and Environmental Sciences of Ukraine, HUTSALENKO Liubov , MARCHUK Uliana ,   SHEE “Kyiv National Economic University named after Vadym Hetman”, STASHENKO Yuliia ,   SHEE “Kyiv National Economic University named after Vadym Hetman”
Published: May 2023

Introduction. Energy is a strategically important industry, the smooth and efficient operation of all spheres of the domestic economy depends on its safe and stable functioning. Problem Statement. The energy system of Ukraine provides the economy not only for its country, but also for the countries of the European Union. However, as a result of a full-scale Russian aggression and massive missile attacks, the systematic supply of electricity in certain locations, which took place during peacetime, is being destroyed. Purpose. To conduct the assessment of the energy system of Ukraine before the invasion and destruction due to Russian aggression, to identify the advantages of using blockchain in the energy and climate sectors to restore energy capacities. Methods. General scientific methods, statistical and economic methods of analysis, comparison, and graphic methods are used. Results. Attention is focused on the role of the energy system in the economy of Ukraine. Changes in the domestic energy system and its synchronization with the harmonized EU network are indicated. The reasons for the decrease in demand for electricity after the full-scale Russian invasion have been revealed. Factors indicating a long period of restoration of the power system have been identified. The structure of generation in Ukraine is given and its component capacities are outlined. TPPs of Ukraine and the possibility of importing lignite and hard coal from Europe to ensure their operation are characterized. Emphasis is placed on the development of renewable energy sources in Ukraine. Conclusions. It has been proven that the restoration of the power system must be carried out taking into account the latest IT technologies using the digital ecosystem. Among many digital technologies, blockchain will help support and optimize evidence-based decision-making in the areas of climate and sustainable energy. Blockchain solutions for the energy transition confirm that this technology has a high potential to be used as the “distributed engine” of the energy community, pointing to it as a tool that will radically change the energy sector.
Mini-Review: brown macroalgae as a promising raw material to produce biostimulants for the agriculture sector
Authors: Kergosien Nolwenn , Stiger-Pouvreau Valérie , Connan Solène , Hennequart Franck , Brébion Jérémy
Published: May 2023

The worldwide growing food demand and the excessive use of synthetic and chemical inputs compel the agricultural sector to find innovative and sustainable solutions to enhance or at least maintain crop yields in times of increased abiotic stresses levels linked to global change. Currently, great research efforts are carried out on brown seaweeds as their environment lead them to produce a broad range of compounds, with osmoregulatory, antioxidant, pro-bacterial, and plant-growth promoting activities. Indeed, numerous studies are looking at different combinations of algal species, extraction processes, plant species and environments of plant culture to highlight the various effects of algal extracts on plant growth and development, and resistance to abiotic stresses. Consequently, a wide variety of novel commercial products are emerging, presenting diversified chemical compositions, formulations and means of application. Such products allow the biostimulation of plants and soil by alleviating abiotic stresses such as drought, frost, and salt. The action of brown macroalgal extracts on plant and soil health has been repeatedly demonstrated, yet the precise relation between the extract chemical composition and its subsequent effect is still to be elucidated, as molecular synergy is suspected to play an important role. In this review, we present the interest of using brown macroalgal extracts to produce biostimulants with beneficial action on soil health, plant growth and development, as well as resistance against abiotic stresses, in relation to the molecular changes occurring.
A mini-review on the emerging role of nanotechnology in revolutionizing orthopedic surgery: challenges and the road ahead
Authors: Deng Yongjun , Zhou Chao , Fu Lifeng , Huang Xiaogang , Liu Zunyong , Zhao Jiayi , Liang Wenqing , Shao Haiyan
Published: May 2023

An emerging application of nanotechnology in medicine currently being developed involves employing nanoparticles to deliver drugs, heat, light, or other substances to specific types of cells (such as cancer cells). As most biological molecules exist and function at the nanoscale, engineering and manipulating matter at the molecular level has many advantages in the field of medicine (nanomedicine). Although encouraging, it remains unclear how much of this will ultimately result in improved patient care. In surgical specialties, clinically relevant nanotechnology applications include the creation of surgical instruments, suture materials, imaging, targeted drug therapy, visualization methods, and wound healing techniques. Burn lesion and scar management is an essential nanotechnology application. Prevention, diagnosis, and treatment of numerous orthopedic conditions are crucial technological aspects for patients’ functional recovery. Orthopedic surgery is a specialty that deals with the diagnosis and treatment of musculoskeletal disorders. In recent years, the field of orthopedics has been revolutionized by the advent of nanotechnology. Using biomaterials comprised of nanoparticles and structures, it is possible to substantially enhance the efficacy of such interactions through nanoscale material modifications. This serves as the foundation for the majority of orthopedic nanotechnology applications. In orthopedic surgery, nanotechnology has been applied to improve surgical outcomes, enhance bone healing, and reduce complications associated with orthopedic procedures. This mini-review summarizes the present state of nanotechnology in orthopedic surgery, including its applications as well as possible future directions.
Sensitive and rapid detection of tetrodotoxin based on gold nanoflower-and latex microsphere-labeled monoclonal antibodies
Authors: Huang Yongming , Xu Aidi , Xu Yang , Wu Huijuan , Sun Menghan , Madushika Lakshani , Wang Rongzhi , Yuan Jun , Wang Shihua , Ling Sumei
Published: May 2023

Tetrodotoxin (TTX) could result in serious diseases due to its extremely high neurotoxicity. Thus, it is of great importance to measure TTX for food safety. In this study, an anti-TTX monoclonal antibody with good specificity and high affinity was used to develop the immunochromatographic test strips (ICTS). Gold nanoflower (AuNF) with multiple branches and latex microsphere (LM) with large particle size as signal reporters were employed for improving the sensitivity of test strips. Both AuNF and LM probes are stable, and the developed ICTS were specific to TTX, demonstrating no cross-reactivity with other marine toxins. The linear range of AuNF- and LM-based strips for TTX was 9.49–330.98 ng/mL and 5.40–443.19 ng/mL, respectively. The limit of detection (LOD) of AuNF- and LM-based strips was determined to be 9.49 ng/mL and 5.40 ng/mL, respectively. In summary, the developed ICTS based on AuNF and LM signal probes displayed enhancement of sensitivity and provided rapid and specific detection of TTX.
Role of UPRmt and mitochondrial dynamics in host immunity: it takes two to tango
Authors: Kumar Manmohan , Sharma Shagun , Mazumder Shibnath
Published: May 2023

The immune system of a host contains a group of heterogeneous cells with the prime aim of restraining pathogenic infection and maintaining homeostasis. Recent reports have proved that the various subtypes of immune cells exploit distinct metabolic programs for their functioning. Mitochondria are central signaling organelles regulating a range of cellular activities including metabolic reprogramming and immune homeostasis which eventually decree the immunological fate of the host under pathogenic stress. Emerging evidence suggests that following bacterial infection, innate immune cells undergo profound metabolic switching to restrain and countervail the bacterial pathogens, promote inflammation and restore tissue homeostasis. On the other hand, bacterial pathogens affect mitochondrial structure and functions to evade host immunity and influence their intracellular survival. Mitochondria employ several mechanisms to overcome bacterial stress of which mitochondrial UPR (UPRmt) and mitochondrial dynamics are critical. This review discusses the latest advances in our understanding of the immune functions of mitochondria against bacterial infection, particularly the mechanisms of mitochondrial UPRmt and mitochondrial dynamics and their involvement in host immunity.
Computational clustering reveals differentiated coronary artery calcium progression at prevalent levels of pulse wave velocity by classifying high-risk patients
Authors: Rousseau-Portalis Maximo , Cymberknop Leandro , Farro Ignacio , Armentano Ricardo
Published: May 2023

Many studies found that increased arterial stiffness is significantly associated with the presence and progression of Coronary Calcium Score (CCS). However, none so far have used machine learning algorithms to improve their value. Therefore, this study aims to evaluate the association between carotid-femoral Pulse Wave Velocity (cfPWV) and CCS score through computational clustering. We conducted a retrospective cross-sectional study using data from a cardiovascular risk screening program that included 377 participants. We used an unsupervised clustering algorithm using age, weight, height, blood pressure, heart rate, and cfPWV as input variables. Differences between cluster groups were analyzed through Chi-square and T-student tests. The association between (i) cfPWV and age groups, (ii) log (CCS) and age groups, and (iii) cfPWV and log(CCS) were addressed through linear regression analysis. Clusters were labeled post hoc based on cardiovascular risk. A “higher-risk group” had significantly higher left (0.76 vs. 0.70 mm, P < 0.001) and right (0.71 vs. 0.66 mm, P = 0.003) intima-media thickness, CCS (42 vs. 4 Agatston units, P = 0.012), and ascending (3.40 vs. 3.20 cm, P < 0.001) and descending (2.60 vs. 2.37 cm, P < 0.001) aorta diameters. Association with age appeared linear for cfPWV and exponential for log (CCS). The progression of the log (CCS) and cfPWV through age groups was steeper in the “higher-risk group” than in the “lower-risk group”. cfPWV strongly correlated with CCS, and CCS progression over cfPWV differed among clusters. This finding could improve PWV as a “gate-keeper” of CCS testing and potentially enhance cardiovascular risk stratification.