bluuebunny/crossref_metadata_2025 huggingface dataset:
Time-dependent mood fluctuations in Antarctic personnel: a meta-analysis
Authors: Hawkes Clare , Norris Kimberley
Published: September 2017

The third-quarter phenomenon is the dominant theoretical model to explain the psychological impacts of deployment in Antarctica on personnel. It posits that detrimental symptoms to functioning, such as negative mood, increase gradually throughout deployment and peak at the third-quarter point, regardless of overall deployment length. However, there is equivocal support for the model. The current meta-analysis included data from 21 studies (involving 1,826 participants) measuring negative mood during deployment to elucidate this discrepancy. Across studies analyses were conducted on three data types: stratified by month using repeated-measured all time points meta-analytic techniques and pre/post-deployment data for summer/winter deployment seasons. Our results did not support the proposed parameters of the third-quarter phenomenon, as negative mood did not peak at the third-quarter point (August/September) of deployment. Overall effect sizes indicated that negative mood was greater at baseline than the end of deployment for summer and winter deployment seasons. These findings have theoretical and practical implications and should be used to guide future research, assisting in the development and modification of pre-existing prevention and intervention programmes to improve well-being and functioning of personnel during Antarctic deployment.
A longitudinal mediation analysis of the effect of negative-self-schemas on positive symptoms via negative affect
Authors: Jaya E. S. , Ascone L. , Lincoln T. M.
Published: September 2017

Background

Cognitive models postulate that negative-self-schemas (NSS) cause and maintain positive symptoms and that negative affect mediates this link. However, only few studies have tested the temporal mediation claim systematically using an appropriate design.

Methods

A longitudinal cohort design in an online community sample (N = 962) from Germany, Indonesia, and the USA was used. NSS, negative affect and positive symptoms were measured at four time-points (T0–T3) over a 1-year period. Cross-lagged panel and longitudinal mediation analyses with structural equation modeling were used to test the temporal mediation.

Results

Independent cross-lagged panel models showed a significant unidirectional longitudinal path from NSS to positive symptoms (T2–T3, β = 0.18, p < 0.01) and bidirectional longitudinal associations from NSS to negative affect (T0–T1, γ = 0.14, p < 0.01) and vice versa (T0–T1, γ = 0.19, p < 0.01). There was also a significant indirect pathway from NSS at baseline via negative affect at T1 and T2 to positive symptoms at T3 (unstandardized indirect effect coefficient = 0.020, p < 0.05, BCa CI 0.004–0.035), indicating mediation.

Conclusions

Our findings support the postulated affective pathway from NSS to positive symptoms via negative affect. Specifically, our data indicate that NSS and negative affect influence each other and build up over the course of several months before leading on to positive symptoms. We conclude that interrupting this process by targeting NSS and negative affect early in the process could be a promising strategy to prevent the exacerbation of positive symptoms.
STATUS OF DISINVESTMENT INITIATIVES IN LATIN AMERICA: RESULTS FROM A SYSTEMATIC LITERATURE REVIEW AND A QUESTIONNAIRE
Authors: Agirrezabal Ion , Burgon Joseph , Stewart Gavin , Gutierrez-Ibarluzea Iñaki
Published: September 2017

Objectives: Disinvestment of existing healthcare technologies that deliver low or no health benefit for their cost can be used as a tool to improve access to effective technologies, while ensuring the long-term sustainability of healthcare systems. The objective of this research was to identify disinvestment initiatives in Latin American countries (LAC).

Methods: First, a systematic literature review (SLR) was conducted. In February 2015, MEDLINE, MEDLINE In-Process, EMBASE, The Cochrane Library, and LILACS were searched for relevant journal articles, including terms related to “disinvestment,” “reallocation,” “obsolete technologies,” and “Latin America.” Additionally, a manual search of documents from Latin American health technology assessment agencies was performed. Second, an online questionnaire was sent to experts in LAC to assess whether unpublished real-life disinvestment initiatives exist. Questionnaire results were collected in September 2015.

Results: From the SLR, 350 records were selected for screening following de-duplication and eleven articles fulfilled inclusion criteria. Only two of these reported information on initiatives potentially identifiable as disinvestment-investment activities in Brazil and Peru. Nine respondents completed the questionnaire, and four reported that disinvestment initiatives had been conducted in their respective organizations in Argentina, Brazil, and Mexico. This lack of agreement between the SLR and the questionnaire responses shows that disinvestment initiatives are ongoing, despite being under reported.

Conclusions: Many challenges need to be overcome for a disinvestment initiative to be successful, and sharing particular experiences with the international community would increase the chances of positive outcomes. The present study highlights the need for publication of such experiences in LAC.
Emerging arboviruses in Quebec, Canada: assessing public health risk by serology in humans, horses and pet dogs
Authors: ROCHELEAU J. P. , MICHEL P. , LINDSAY L. R. , DREBOT M. , DIBERNARDO A. , OGDEN N.H , FORTIN A. , ARSENAULT J.
Published: September 2017

Periodic outbreaks of West Nile virus (WNV), Eastern equine encephalitis virus (EEEV) and to a lesser extent, California serogroup viruses (CSGV), have been reported in parts of Canada in the last decade. This study was designed to provide a broad assessment of arboviral activity in Quebec, Canada, by conducting serological surveys for these arboviruses in 196 horses, 1442 dogs and 485 humans. Sera were screened by a competitive enzyme linked immunosorbent assay and positive samples confirmed by plaque reduction neutralisation tests. The percentage of seropositive samples was 83·7%, 16·5%, 7·1% in horses, 18·8%, 0·6%, 0% in humans, 11·7%, 3·1%, 0% in adult dogs and 2·9%, 0·3%, 0% in juvenile dogs for CSGV, WNV and EEEV, respectively. Serological results in horses and dogs appeared to provide a meaningful assessment of risk to public health posed by multiple arboviruses.
Bisections of Graphs Without Short Cycles
Authors: FAN GENGHUA , HOU JIANFENG , YU XINGXING
Published: September 2017

Bollobás and Scott (Random Struct. Alg.21(2002) 414–430) asked for conditions that guarantee a bisection of a graph withmedges in which each class has at most (1/4+o(1))medges. We demonstrate that cycles of length 4 play an important role for this question. LetGbe a graph withmedges, minimum degree δ, and containing no cycle of length 4. We show that if (i)Gis 2-connected, or (ii) δ ⩾ 3, or (iii) δ ⩾ 2 and the girth ofGis at least 5, thenGadmits a bisection in which each class has at most (1/4+o(1))medges. We show that each of these conditions are best possible. On the other hand, a construction by Alon, Bollobás, Krivelevich and Sudakov shows that for infinitely manymthere exists a graph withmedges and girth at least 5 for which any bisection has at least (1/4−o(1))medges in one of the two classes.
Incident-driven Democracy at Europe’s Edge. The Case of Bosnia-Herzegovina
Authors: Dejaeghere Yves , Vermeersch Peter
Published: September 2017

In recent years, several instances of social protest in Europe have transformed into new initiatives for citizens’ participation (e.g. citizens’ assemblies, deliberative forums, etc). Can such a transformation also take place in the more volatile political settings of a post-conflict democratizing state? We turn our attention to the plenums in Bosnia-Herzegovina, which were spontaneously organized citizens’ assemblies in the spring of 2014. We conclude that these plenums were a form of incident-driven democracy. In a country where the regular institutions of representative democracy continue to be widely mistrusted and civil society organizations, which normally have a mitigating role between citizens and state institutions in times of crisis, are weak, untrustworthy or absent, such incidental institutions have an important role to play. Their effect in the short term may be limited, but if new opportunities arise they may function as a useful memory for activists, a model for citizens’ participation outside elections, and therefore an instigator of further democratization.
Nutzung von psychometrischem Feedback als empirische Unterstützung des Supervisionsprozesses bei Ausbildungstherapien
Authors: Rubel Julian A. , Zimmermann Dirk , Deisenhofer Anne-Katharina , Müller Viola , Lutz Wolfgang
Published: September 2017

Zusammenfassung. Theoretischer Hintergrund: Trotz der gut belegten generellen Wirksamkeit von Psychotherapie wird die Zahl der Patienten, die nicht auf eine Therapie ansprechen oder sich sogar im Verlauf verschlechtern, auf etwa ein Drittel geschätzt. Da Therapeuten im Vergleich zu empirischen Algorithmen weniger gut in der Lage sind negative Entwicklungen zu entdecken oder zu prognostizieren, brauchen sie zusätzliche Unterstützung in Form von kontinuierlichen Rückmeldungen über den Fortschritt ihrer Patienten. Solche Feedbackinterventionen können als empirisch basierte Unterstützung des Supervisions- oder Intervisionsprozesses verstanden werden. Diese Interventionen haben ihre Wirksamkeit zur Reduktion therapeutischer Misserfolge in zahlreichen Einzelstudien und Meta-Analysen wiederholt zeigen können. Fragestellung: Wie nutzen Therapeuten ein solches Feedback in ihrer praktischen Arbeit und in welchem Ausmaß spielen Therapeutenfaktoren dabei eine Rolle? Methode: In der vorliegenden Studie wurden 72 Therapeuten für 648 ihrer Patienten unmittelbar nach der Therapie dazu befragt, wie sie das psychometrische Feedback genutzt haben. Therapeutenunterschiede wurden mittels Mehrebenenmodellen ermittelt. Ergebnisse: Es konnte gezeigt werden, dass Therapeuten für einen Großteil ihrer Patienten das Feedback verwendeten. In etwa einem Drittel der Fälle gab es den Therapeuten den Anstoß zusätzliche Hilfen (z. B. Supervision/Intervision) zu beanspruchen. Ähnlich einer personengestützten Supervision wurde für über die Hälfte der Patienten das Feedback genutzt um therapeutische Interventionen anzupassen. Ob und in welcher Form es genutzt wurde hing jedoch stark von dem Therapeuten ab. Je nach Verwendungsart konnten Therapeutenunterschiede zwischen 27 % und 52 % der Feedbacknutzung erklären. Die Wahrscheinlichkeit, dass Therapeuten die Nutzungsmöglichkeiten des Feedbacks anwendeten war größer, wenn diese angaben im Durchschnitt zufriedener mit den grafischen Rückmeldungen zu sein. Schlussfolgerungen: Diese Ergebnisse machen deutlich, dass es zu einem großen Teil nicht nur vom Therapieverlauf oder den Charakteristika der jeweiligen Patienten abhängt wie Therapeuten das Feedback nutzen, sondern auch von Variablen, die den Therapeuten betreffen.
Convergent evolution of Y chromosome gene content in flies
Authors: Mahajan Shivani , Bachtrog Doris
Published: September 2017

Sex-chromosomes have formed repeatedly across Diptera from ordinary autosomes, and X-chromosomes mostly conserve their ancestral genes. Y-chromosomes are characterized by abundant gene-loss and an accumulation of repetitive DNA, yet the nature of the gene repertoire of fly Y-chromosomes is largely unknown. Here we trace gene-content evolution of Y-chromosomes across 22 Diptera species, using a subtraction pipeline that infers Y genes from male and female genome, and transcriptome data. Few genes remain on old Y-chromosomes, but the number of inferred Y-genes varies substantially between species. Young Y-chromosomes still show clear evidence of their autosomal origins, but most genes on old Y-chromosomes are not simply remnants of genes originally present on the proto-sex-chromosome that escaped degeneration, but instead were recruited secondarily from autosomes. Despite almost no overlap in Y-linked gene content in different species with independently formed sex-chromosomes, we find that Y-linked genes have evolved convergent gene functions associated with testis expression. Thus, male-specific selection appears as a dominant force shaping gene-content evolution of Y-chromosomes across fly species.
A Tomato Spotted Wilt Virus S RNA-based Replicon System in Yeast
Authors: Ishibashi Kazuhiro , Matsumoto-Yokoyama Eiko , Ishikawa Masayuki
Published: September 2017

Tomato spotted wilt virus (TSWV) is a negative-strand RNA virus of the order Bunyavirales, family Tospoviridae, genus Orthotospovirus. TSWV infects a broad range of plant species, causing serious economic losses. Despite its agronomic importance, molecular biological understanding of TSWV has been limited, partly due to the lack of a reverse genetics system, which would enable genetic manipulation of the virus. Here, we report that RNA synthesis by TSWV RNA polymerase occurs in the yeast Saccharomyces cerevisiae using a segment of the TSWV genome, S RNA expressed from cloned cDNA, as a template. Viral nucleocapsid protein was required for RNA synthesis. Replacement of the protein-coding and intergenic regions of TSWV S RNA by a yellow fluorescent protein (YFP)-coding sequence drastically increased the accumulation of both sense and antisense strands of the RNA, showing that this RNA was replicated. Using this system, we revealed that efficient RNA synthesis by TSWV RNA polymerase in yeast requires the 5′-terminal 17-nt and 3′-terminal ~50-nt regions of the TSWV S cRNA (complementary RNA to the genomic RNA) template.
A Point-based Mortality Prediction System for Older Adults with Diabetes
Authors: Chang Y. K. , Huang L. F. , Shin S. J. , Lin K. D. , Chong K. , Yen F. S. , Chang H. Y. , Chuang S. Y. , Hsieh T. J. , Hsiung C. A. , Hsu C. C.
Published: September 2017

The mortality prediction models for the general diabetic population have been well established, but the corresponding elderly-specific model is still lacking. This study aims to develop a mortality prediction model for the elderly with diabetes. The data used for model establishment were derived from the nationwide adult health screening program in Taiwan in 2007–2010, from which we applied a 10-fold cross-validation method for model construction and internal validation. The external validation was tested on the MJ health screening database collected in 2004–2007. Multivariable Cox proportional hazards models were used to predict five-year mortality for diabetic patients ≥65 years. A total of 220,832 older subjects with diabetes were selected for model construction, of whom 23,241 (10.5%) died by the end of follow-up (December 31, 2011). The significant predictors retained in the final model included age, gender, smoking status, body mass index (BMI), fasting glucose, systolic and diastolic blood pressure, leukocyte count, liver and renal function, total cholesterol, hemoglobin, albumin, and uric acid. The Harrell’s C in the development, internal-, and external-validation datasets were 0.737, 0.746, and 0.685, respectively. We established an easy-to-use point-based model that could accurately predict five-year mortality risk in older adults with diabetes.
Therapeutic PCL scaffold for reparation of resected osteosarcoma defect
Authors: Palamà Ilaria E. , Arcadio Valentina , D’Amone Stefania , Biasiucci Mariano , Gigli Giuseppe , Cortese Barbara
Published: September 2017

Osteosarcomas are highly malignant tumors, which develop rapid growth and local infiltration, inducing metastases that spread primarily in the lung. Treatment of these tumors is mainly based on pre- and post-operative chemotherapy and surgery of the primary tumor. Surgical resection though, generates bone defects. Reparation of these weaknesses presents formidable challenges to orthopedic surgery. Medicine regenerative grafts that act as both tumor therapy with constant local drug delivery and tissue regeneration may provide a new prospect to address this need. These implants can provide sustained drug release at the cancer area, decreasing systemic second effects such as inflammation, and a filling of the resected tissues with regenerative biomaterials. In this study microporous poly-ε-caprolactone (PCL) scaffolds have been developed for sustained local release of anti-inflammatory drug dexamethasone (DXM), used as drug model, in cancer medicine regenerative field. The microporous PCL matrix of the scaffolds supported the attachment, proliferation and osteogenic differentiation of osteoblast-like cells, while the polyelectrolyte multilayers, anchored to the inner pore surfaces, sustained locally DXM release. These microporous scaffolds demonstrate the ability to deliver DXM as a localized tumor therapy and to promote proliferation and differentiation of osteoblast-like cells in vitro.
Effects of N-Glycan Composition on Structure and Dynamics of IgG1 Fc and Their Implications for Antibody Engineering
Authors: Lee Hui Sun , Im Wonpil
Published: September 2017

Immunoglobulin G1 (IgG1), a subclass of human serum antibodies, is the most widely used scaffold for developing monoclonal antibodies to treat human diseases. The composition of asparagine(N)297-linked glycans can modulate the binding affinity of IgG1 Fc to Fc γ receptors, but it is unclear how the structural modifications of N-glycan termini, which are distal from the binding interface, contribute to the affinity. Through atomistic molecular dynamics simulations of a series of sequentially truncated high-mannose IgG1 Fc glycoforms, we found that the C′E loop and the Cγ2-Cγ3 orientation are highly dynamic, and changes in N-glycan composition alter their conformational ensembles. High-mannose glycoform preferentially samples conformations that are more competent to FcγRIIIa binding, compared to the truncated glycoforms, suggesting a role of IgG1 Fc N-glycan in optimizing the interface with the Fc receptor for efficient binding. The trajectory analyses also reveal that the N-glycan has large amplitude motions and the carbohydrate moiety interconverts between Fc-bound and unbound forms, enabling enzymatic modification of the glycan termini.
Tuning the electrical transport of type II Weyl semimetal WTe2 nanodevices by Ga+ ion implantation
Authors: Fu Dongzhi , Zhang Bingwen , Pan Xingchen , Fei Fucong , Chen Yongda , Gao Ming , Wu Shuyi , He Jian , Bai Zhanbin , Pan Yiming , Zhang Qinfang , Wang Xuefeng , Wu Xinglong , Song Fengqi
Published: September 2017

Here we introduce lattice defects in WTe2 by Ga+ implantation (GI), and study the effects of defects on the transport properties and electronic structures of the samples. Theoretical calculation shows that Te Frenkel defects is the dominant defect type, and Raman characterization results agree with this. Electrical transport measurements show that, after GI, significant changes are observed in magnetoresistance and Hall resistance. The classical two-band model analysis shows that both electron and hole concentration are significantly reduced. According to the calculated results, ion implantation leads to significant changes in the band structure and the Fermi surface of the WTe2. Our results indicate that defect engineering is an effective route of controlling the electronic properties of WTe2 devices.
Exogenous DCPTA Ameliorates Simulated Drought Conditions by Improving the Growth and Photosynthetic Capacity of Maize Seedlings
Authors: Xie Tenglong , Gu Wanrong , Meng Yao , Li Jing , Li Lijie , Wang Yongchao , Qu Danyang , Wei Shi
Published: September 2017

Previous reports have indicated that 2-(3,4-dichlorophenoxy)triethylamine (DCPTA) can promote the growth and photosynthetic capacity of plants. However, only a small number of these studies have focused on crops, and few reports have focused on whether DCPTA affects stress tolerance. In this study, maize (Zea mays L.) seedlings were pretreated with or without DCPTA and then exposed to drought stress in a controlled growth room for 7 days, and the growth and photosynthesis indexes of the seedlings were investigated. The DCPTA treatment partly counteracted the observed decreases in biomass, net photosynthetic rate (Pn), stomatal conductance (Gs), transpiration rate (Tr), effective photochemical efficiency of photosystem II (ΦPSII), maximum photochemical efficiency of PSII (Fv/Fm), non-photochemical quenching (NPQ), and photosynthetic pigment content and increased the minimal fluorescence (Fo) induced by drought stress. The DCPTA treatment also alleviated the damage induced by drought stress in the photosynthetic apparatus. In addition, DCPTA pretreatment simultaneously increased the root size (e.g., the length, surface area, and volume) and root hydraulic conductivity, which promoted the maintenance of higher relative leaf water contents (RLWCs) under stress conditions. These results indicate that exogenous DCPTA ameliorates simulated drought conditions by improving the growth and photosynthetic capacity of maize seedlings.
Beneficial effects of Red Light-Emitting Diode treatment in experimental model of acute lung injury induced by sepsis
Authors: Costa Silvia Goes , Barioni Éric Diego , Ignácio Aline , Albuquerque Juliana , Câmara Niels Olsen Saraiva , Pavani Christiane , Vitoretti Luana Beatriz , Damazo Amílcar Sabino , Farsky Sandra Helena Poliselli , Lino-dos-Santos-Franco Adriana
Published: September 2017

Sepsis is a severe disease with a high mortality index and it is responsible for the development of acute lung injury (ALI). We evaluated the effects of light-emitting diode (LED) on ALI induced by sepsis. Balb-c mice were injected with lipopolysaccharide or saline and then irradiated or not with red LED on their tracheas and lungs for 150 s, 2 and 6 h after LPS injections. The parameters were investigated 24 h after the LPS injections. Red LED treatment reduced neutrophil influx and the levels of interleukins 1β, 17 A and, tumor necrosis factor-α; in addition to enhanced levels of interferon γ in the bronchoalveolar fluid. Moreover, red LED treatment enhanced the RNAm levels of IL-10 and IFN-γ. It also partially reduced the elevated oxidative burst and enhanced apoptosis, but it did not alter the translocation of nuclear factor κB, the expression of toll-like receptor 4 (TLR4), as well as, oedema or mucus production in their lung tissues. Together, our data has shown the beneficial effects of short treatment with LED on ALI that are caused by gram negative bacterial infections. It is suggested that LED applications are an inexpensive and non-invasive additional treatment for sepsis.
Deep convolutional neural networks for Raman spectrum recognition: a unified solution
Authors: Liu Jinchao , Osadchy Margarita , Ashton Lorna , Foster Michael , Solomon Christopher J. , Gibson Stuart J.
Published: September 2017

Classification of unprocessed Raman spectra using a convolutional neural network.
Advantages of aptamers as ligands upon protein detection by AFM-based fishing
Authors: Pleshakova T. O. , Kaysheva A. L. , Bayzyanova J. M. , Anashkina A. S. , Uchaikin V. F. , Shumov I. D. , Ziborov V. S. , Konev V. A. , Archakov A. I. , Ivanov Yu. D.
Published: September 2017

AFM chip with immobilized aptamers can be used for HCVcoreAg detection in solution.
ZnO quantum dot-decorated carbon nanofibers derived from electrospun ZIF-8/PVA nanofibers for high-performance energy storage electrodes
Authors: Lee Gyeongseop , Seo Young Deok , Jang Jyongsik
Published: September 2017

We for the first time prepared hybrid structures of ZnO QDs@carbons and carbon nanofibers using electrospun MOF materials and evaluated their electrochemical performances.
Complexity of two-dimensional self-assembled arrays at surfaces
Authors: Pfeiffer Constance R. , Pearce Nicholas , Champness Neil R.
Published: September 2017

The developing field of complexity in self-assembled systems on surfaces is discussed.
Understanding the role of water in 1,10-phenanthroline monohydrate
Authors: Braun Doris E. , Schneeberger Anna , Griesser Ulrich J.
Published: September 2017

This study unravels why 1,10-phenanthroline forms a very stable stoichiometric channel hydrate withZ′ > 1.
Ligand displacement induced morphologies in block copolymer/quantum dot hybrids and formation of core–shell hybrid nanoobjects
Authors: Singh Sajan , Samanta Pratick , Srivastava Rajiv , Horechyy Andriy , Reuter Uta , Stamm Manfred , Chen Hsin-Lung , Nandan Bhanu
Published: September 2017

This article reports on the ligand displacement induced morphologies in block copolymer/quantum dot hybrids and further formation of core–shell nano-objects from them.
A study on an unusual SN2 mechanism in the methylation of benzyne through nickel-complexation
Authors: Hatakeyama Makoto , Sakamoto Yuki , Ogata Koji , Sumida Yuto , Sumida Tomoe , Hosoya Takamitsu , Nakamura Shinichiro
Published: September 2017

Joint research on the valence state of a benzyne–Ni complex (Ni0: η2-structure or NiII: metallacycle) and the methylation with iodomethane.
Introduction to a themed issue of Chemical Society Reviews on artificial photosynthesis
Authors: Brudvig Gary W. , Campagna Sebastiano
Published: September 2017

Guest editors Gary W. Brudvig and Sebastiano Campagna introduce the artificial photosynthesis themed issue of Chemical Society Reviews.
DFT and experimental analysis of aluminium chloride as a Lewis acid proton carrier catalyst for dimethyl carbonate carboxymethylation of alcohols
Authors: Jin Saimeng , Tian Yin , McElroy Con Robert , Wang Dongqi , Clark James H. , Hunt Andrew J.
Published: September 2017

In silico and physical experimental data led to a potential acid (AlCl3) catalysed mechanism for DMC carboxymethylation.
Synthesis and oxidation of phosphine cations
Authors: Mehta Meera , Johnstone Timothy C. , Lam Jolie , Bagh Bidraha , Hermannsdorfer André , Driess Matthias , Stephan Douglas W.
Published: September 2017

Cationic phosphines of the form [(L)PPh2]+ are prepared from Ph2PCl and carbenes (L), including a chiral bis(oxazoline)-based carbene, a cyclic(alkyl)(amino) carbene, and a 1,2,3-triazolium-derived carbene. A related dication was prepared from PhPCl2 and a bis-carbene. The monocations, but not the dication, can be oxidized with XeF2.
Constructing hierarchical porous nanospheres for versatile microwave response approaches: the effect of architectural design
Authors: Quan Bin , Liang Xiaohui , Yi Heng , Gong He , Ji Guangbin , Chen Jiabin , Xu Guoyue , Du Youwei
Published: September 2017

Hierarchical porous nanospheres via functionalized structural design were obtained to achieve a promising microwave absorption performance.
MoS2/TiO2 heterostructures as nonmetal plasmonic photocatalysts for highly efficient hydrogen evolution
Authors: Guo L. , Yang Z. , Marcus K. , Li Z. , Luo B. , Zhou L. , Wang X. , Du Y. , Yang Y.
Published: September 2017

Periodically patterned MoS2/TiO2 heterostructures were rationally designed as nonmetal plasmonic photocatalysts for highly efficient hydrogen evolution.
Orange juice modulates proinflammatory cytokines after high-fat saturated meal consumption
Authors: Rocha Daniela M. U. P. , Lopes Lílian L. , da Silva Alessandra , Oliveira Leandro L. , Bressan Josefina , Hermsdorff Helen Hermana M.
Published: September 2017

We aimed to evaluate the postprandial secretion of inflammatory markers induced by SFA or MUFA high-fat meal consumption and whether orange juice intake could modulate this induction.
Enabling electrical biomolecular detection in high ionic concentrations and enhancement of the detection limit thereof by coupling a nanofluidic crystal with reconfigurable ion concentration polarization
Authors: Ouyang Wei , Han Jongyoon , Wang Wei
Published: September 2017

Electrical biosensing in high ionic concentrations is enabled by the depletion effect of ion concentration polarization and further enhanced by its enrichment effect.
Experimental verification of simultaneous desalting and molecular preconcentration by ion concentration polarization
Authors: Kim Wonseok , Park Sungmin , Kim Kihong , Kim Sung Jae
Published: September 2017

This study enables the perfect recovery of target analyte and the removal of unnecessary salts simultaneously, which would be a key operational strategy of various refinery/purification applications.
Cancer nanomedicine: from PDGF targeted drug delivery
Authors: Rejeeth Chandrababu , Vivek Raju , NipunBabu Varukattu , Sharma Alok , Ding Xianting , Qian Kun
Published: September 2017

An innovative approach for the distinctively efficient action of smart targeted drug delivery to a specific cell type is obtained through the modification of the surface of nanoparticles.
Syntheses and characterization of monobasic tridentate Cu(ii) Schiff-base complexes for efficient oxidation of 3,5-di-tert-butylcatechol and oxidative bromination of organic substrates
Authors: Kumari Sweta , Mahato Arun Kumar , Maurya Abhishek , Singh Vijay Kumar , Kesharwani Neha , Kachhap Payal , Koshevoy Igor O. , Haldar Chanchal
Published: September 2017

Enhanced bifunctional catalytic activities are shown by monobasic tridentate Cu(ii) Schiff-base complexes.
Polymer monolith containing an embedded covalent organic framework for the effective enrichment of benzophenones
Authors: Wang Huiqi , Li Zheng , Feng Wei , Jia Qiong
Published: September 2017

A COF modified poly(glycidyl methacrylate–ethylene dimethacrylate) monolith was prepared and used for the microextraction of benzophenones in urine and serum samples.
Selection of catalytically active elements for removing NO and CO from flue gas at low temperatures
Authors: Liu Kaijie , Yu Qingbo , Liu Jinlin , Wang Kun , Han Zhicheng , Xuan Yanni , Qin Qin
Published: September 2017

The metal elements Mn, Cu, Pb and V have been selected for removing NO and CO via a thermodynamic study.
Molecular hybrid design, synthesis and biological evaluation of N-phenyl sulfonamide linked N-acyl hydrazone derivatives functioning as COX-2 inhibitors: new anti-inflammatory, anti-oxidant and anti-bacterial agents
Authors: Gorantla Vasubabu , Gundla Rambabu , Jadav Surender Singh , Anugu Sreenivasa Reddy , Chimakurthy Jithendra , Nidasanametla Satya Kameswararao , Korupolu Raghubabu
Published: September 2017

The design, synthesis and biological evaluation of the anti-inflammatory activities of novelN-phenyl sulfonamide linkedN-acylhydrazones (NPS–NAH) have been reported.
A binder-free NiCo2O4nanosheet/3D elastic N-doped hollow carbon nanotube sponge electrode with high volumetric and gravimetric capacitances for asymmetric supercapacitors
Authors: Tong Hao , Yue Shihong , Lu Liang , Jin Fengqiao , Han Qiwei , Zhang Xiaogang , Liu Jie
Published: September 2017

To increase the volumetric and gravimetric capacitances of supercapacitors, a new class of electrode materials with high electrochemical activity and favorable structures is extremely desired.
Annealing and polycrystallinity effects on the thermal conductivity of supported CVD graphene monolayers
Authors: Raja Shyamprasad N. , Osenberg David , Choi Kyoungjun , Park Hyung Gyu , Poulikakos Dimos
Published: September 2017

Thermal conductivity of supported CVD graphene is significantly suppressed after annealing and greater polycrystallinity of graphene augments this effect.
Glucose oxidase and polyacrylic acid based water swellable enzyme–polymer conjugates for promoting glucose detection
Authors: Ji Jungyeon , Joh Han-Ik , Chung Yongjin , Kwon Yongchai
Published: September 2017

Glucose oxidase and polyacrylic acid based conjugate shows superior catalytic activity due to its high water swellability. The conjugate absorbs many glucose molecules with rapid transfer rate. Desirable reactions are accordingly promoted.
Quantum confinement induced ultra-high intensity interfacial radiative recombination in nanolaminates
Authors: Li Jin , Bi Xiaofang
Published: September 2017

Interfacial emissions of different bands are achieved in nanolaminate systems by introducing quantum confinement effect.
Catalytic approaches to assemble cyclobutane motifs in natural product synthesis
Authors: Wang Meng , Lu Ping
Published: September 2017

New strategies based on transition-metal catalysis or organocatalysis have provided new perspectives into the total synthesis of cyclobutane-containing natural products.
A g-C3N4/rGO nanocomposite as a highly efficient metal-free photocatalyst for direct C–H arylation under visible light irradiation
Authors: Cai Xiaohui , Liu Hanwen , Zhi Lihua , Wen Huang , Yu Ailing , Li Lianhua , Chen Fengjuan , Wang Baodui
Published: September 2017

A metal-free highly efficient sandwich structured g-C3N4/rGO photocatalyst for direct C–H arylation under visible light irradiation has been reported.
Solvent-induced diversity of luminescent metal–organic frameworks based on different secondary building units
Authors: Wang Lu , Yang Guo-Ping , Yan Yang-Tian , Jin Jing , Ning Yan , Wang Yao-Yu
Published: September 2017

New complexes with SBUs were successfully assembled based on 5′-carboxyl-(1,1′-3′,1′′-terphenyl)-4,4′′-dicarboxylic acid and the CO2 storage properties were researched.
The effect of defects on the interfacial mechanical properties of graphene/epoxy composites
Authors: Li Maoyuan , Zhou Helezi , Zhang Yun , Liao Yonggui , Zhou Huamin
Published: September 2017

The effects of defects on the interfacial mechanical properties of graphene/epoxy are systematically investigated by molecular dynamic simulations.
Promotion effect of water in catalytic fireplace soot oxidation over silver and platinum
Authors: Shromova O. A. , Kinnunen N. M. , Pakkanen T. A. , Suvanto M.
Published: September 2017

The activity of the catalysts in the fireplace soot oxidation depends on water content in the gas feed. Water is partially dissociated with formation of hydroxyls over silver and platinum, which promote soot oxidation.
A modular route to boron doped PAHs by combining borylative cyclisation and electrophilic C–H borylation
Authors: Crossley D. L. , Kahan R. J. , Endres S. , Warner A. J. , Smith R. A. , Cid J. , Dunsford J. J. , Jones J. E. , Vitorica-Yrezabal I. , Ingleson M. J.
Published: September 2017

Starting from simple alkynes, sequential borylative cyclisation/electrophilic C–H borylation represents a simple modular route to novel B-doped PAHs.
Chain dynamics and nanoparticle motion in attractive polymer nanocomposites subjected to large deformations
Authors: Senses Erkan , Tyagi Madhusudan , Natarajan Bharath , Narayanan Suresh , Faraone Antonio
Published: September 2017

A neutron scattering investigation on polymer nanocomposites reveals shear-induced changes in segmental dynamics.
Fabrication of an advanced asymmetric supercapacitor based on a microcubical PB@MnO2hybrid and PANI/GNP composite with excellent electrochemical behaviour
Authors: Das Amit Kumar , Bera Ranadip , Maitra Anirban , Karan Sumanta Kumar , Paria Sarbaranjan , Halder Lopamudra , Si Suman Kumar , Bera Aswini , Khatua Bhanu Bhusan
Published: September 2017

Metal Organic Framework based supercapacitors are one of the best energy storage devices for future portable electronics.
Surfactant-free synthesis of a nanoperforated graphene/nitrogen-doped carbon nanotube composite for supercapacitors
Authors: Choi Yeon Jun , Kim Hyun-Kyung , Lee Suk-Woo , Kim Young Hwan , Youn Hee-Chang , Roh Kwang Chul , Kim Kwang-Bum
Published: September 2017

A nanoperforated graphene/carbon nanotube (PG/CNT) composite is fabricated by electrostatic interaction of graphene oxide (GO) and nitrogen-doped CNTs, and subsequent catalytic carbon gasification.
Efficient fullerene-free solar cells with wide optical band gap polymers based on fluorinated benzotriazole and asymmetric benzodithiophene
Authors: Liu Zhe , Liu Deyu , Zhang Kaili , Zhu Tingting , Zhong Yaqian , Li Feng , Li Yonghai , Sun Mingliang , Yang Renqiang
Published: September 2017

An asymmetric benzodithiophene polymer achieved around 10% PCE with an ITIC acceptor.
Dysregulation of POPDC1 promotes breast cancer cell migration and proliferation
Authors: Amunjela Johanna Ndamwena , Tucker Steven John
Published: September 2017

Breast cancer subtypes such as triple-negative that lack the expression of oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor 2 receptor (HER2), remain poorly clinically managed due to a lack of therapeutic targets. This necessitates identification and validation of novel targets. Suppression of Popeye domain-containing protein 1 (POPDC1) is known to promote tumorigenesis and correlate to poor clinical outcomes in various cancers, and also promotes cardiac and skeletal muscle pathologies. It remains to be established whether POPDC1 is dysregulated in breast cancer, and whether overcoming the dysregulation of POPDC1 could present a potential therapeutic strategy to inhibit breast tumorigenesis. We assessed the potential of POPDC1 as a novel target for inhibiting breast cancer cell migration and proliferation. POPDC1 was significantly suppressed with reduced cell membrane localization in breast cancer cells. Furthermore, functional suppression of POPDC1 promoted breast cancer cell migration and proliferation, which were inhibited by POPDC1 overexpression. Finally, cAMP interacts with POPDC1 and up-regulates its expression in breast cancer cells. These findings suggest that POPDC1 plays a role in breast tumorigenesis and represents a potential therapeutic target or biomarker in breast cancer medicine.
Voltage stability margin improvement using hybrid non‐linear programming and modified binary particle swarm optimisation algorithm considering optimal transmission line switching
Authors: Nojavan Morteza , Seyedi Heresh , Mohammadi‐Ivatloo Behnam
Published: September 2017

A new method is proposed for economic improvement of voltage stability margin. The preventive control facilities include demand response, active/reactive generation rescheduling and load shedding. Transmission line switching is also considered as a new solution for economic improvement of voltage stability margin. The best candidate transmission lines for switching action are selected using modified binary particle swarm optimisation algorithm and the voltage stability subproblem is formulated as non‐linear programming model. In order to verify effectiveness of the proposed method, comprehensive simulations are performed on the IEEE 118‐bus test system. The results indicate high efficiency of the proposed method in identifying the best lines and also decreasing the cost of voltage stability margin improvement. As a result, for the same voltage stability margin, the cost is decreased using optimal transmission line switching.
Circularly‐polarised cavity‐backed wearable antenna in SIW technology
Authors: Moro Riccardo , Agneessens Sam , Rogier Hendrik , Bozzi Maurizio
Published: September 2017

This study presents a circularly‐polarised substrate‐integrated waveguide (SIW) antenna implemented using a textile substrate and operating at 2.45 GHz, in the industrial, scientific, and medical frequency band. The antenna topology is based on a folded cavity with an annular ring as a radiating element, and it permits to obtain compact size and low sensitivity to the environment, without deteriorating the radiating performance. These characteristics, together with the choice of adopting a textile substrate, make the SIW antenna suitable for the integration in wearable systems for body‐centric applications. The electromagnetic performance of the proposed antenna achieved in simulations was verified through the measurement of the device in an anechoic chamber. The circularly‐polarised antenna exhibits a maximum gain of 6.5 dBi, a radiation efficiency of 73% and a very high front‐to‐back ratio.
Seasonal evolution of C2N2, C3H4, and C4H2 abundances in Titan’s lower stratosphere
Authors: Sylvestre M. , Teanby N. A. , Vinatier S. , Lebonnois S. , Irwin P. G. J.
Published: September 2017

Aims. We study the seasonal evolution of Titan’s lower stratosphere (around 15 mbar) in order to better understand the atmospheric dynamics and chemistry in this part of the atmosphere.

Methods. We analysed Cassini/CIRS far-IR observations from 2006 to 2016 in order to measure the seasonal variations of three photochemical by-products: C4H2, C3H4, and C2N2.

Results. We show that the abundances of these three gases have evolved significantly at northern and southern high latitudes since 2006. We measure a sudden and steep increase of the volume mixing ratios of C4H2, C3H4, and C2N2 at the south pole from 2012 to 2013, whereas the abundances of these gases remained approximately constant at the north pole over the same period. At northern mid-latitudes, C2N2 and C4H2 abundances decrease after 2012 while C3H4 abundances stay constant. The comparison of these volume mixing ratio variations with the predictions of photochemical and dynamical models provides constraints on the seasonal evolution of atmospheric circulation and chemical processes at play.
Short-Term Perioperative Outcomes and Complications in Chronic Immunosuppressant Users following Total Hip Arthroplasty
Authors: Curtis Gannon , Chughtai Morad , Khlopas Anton , George Jaiben , Sodhi Nipun , Harwin Steven , Bonutti Peter , Barsoum Wael , Higuera Carlos , Mont Michael
Published: September 2017

As the rate of total hip arthroplasties (THA) being performed continues to increase, orthopaedic surgeons are likely to operate on patients who use systemic immunosuppressants for a variety of ailments. It may be necessary to continue these medications perioperatively, and it has been reported that they may affect post-operative outcomes. The authors proposed the following questions: (1) Are perioperative outcomes (i.e., operative time, lengths-of-stay, and discharge disposition) affected by chronic immunosuppressant use during THA, and (2) does chronic immunosuppressant use increase the rate of complications within 30-days of THA? The American College of Surgeons National Surgical Quality Improvement Program database was used to identify all THAs from 2008 to 2014. Only osteoarthritis diagnoses were included, and any emergency or concurrent surgeries were excluded. The authors identified 64,796 cases that met the inclusion/exclusion criteria. Prior to surgery, 1,900 patients used chronic immunosuppressants, while 62,896 patients did not use immunosuppressants. Lengths-of-stay, operative time, discharge destination, and 30-day complication rates were the measured perioperative outcomes. To determine significant outcome differences between cohorts, univariate analysis was applied. Next, multivariate regression analysis helped determine if immunosuppressant use independently increased the risk for the measured outcomes and complications. Chronic immunosuppressant users were at higher risk of certain adverse perioperative outcomes and short-term complications. Compared with the control group, immunosuppressant users were more likely to be discharged to a non-home facility (odds ratio [OR]: 1.16; 95% confidence interval [CI]: 1.03–1.31). These patients also had greater rates of septic shock (OR: 2.88; 95% CI: 1.08–7.67) and 30-day readmission (OR: 1.37; 95% CI: 1.10–1.70). Chronic immunosuppressant use leads to higher rates of complications and adverse outcomes following THA. Adverse outcomes related to immunosuppressant use included higher rates of non-home discharge. Complications related to immunosuppressant use included septic shock and 30-day readmission.
The Effect of Delayed Cord Clamping on Moderate and Early Late-Preterm Infants
Authors: Qin Huanying , Nguyen Elizabeth , Inzer Robert , Chiruvolu Arpitha
Published: September 2017

Objective This study aims to evaluate the clinical consequences of protocol-driven delayed umbilical cord clamping (DCC) implementation in moderate and early late-preterm (MELP) infants born between 320/7 and 346/7 weeks gestation.

Study Design We conducted a prospective cohort study with a historic control cohort comparison. The prospective study period was 1 year when DCC was performed for 60 seconds duration (DCC cohort, n = 106). The study period for historic control cohort with no DCC was also 1 year before DCC implementation (historic cohort, n = 137).

Results The mean hematocrit at birth was significantly higher in the DCC cohort compared with the historic cohort (49.1 ± 14.9 vs. 45.7 ± 15.7; p = 0.01). Fewer infants in the DCC cohort were admitted to neonatal intensive care unit (NICU) on respiratory support compared with the historic cohort (17.9 vs. 29.9%; p = 0.04). The incidence of respiratory distress syndrome was significantly lower in the DCC cohort compared with the historic cohort (2.8 vs. 14.6%; p = 0.002). There were no differences in the incidence of phototherapy or NICU length of stay (LOS) between groups.

Conclusion In MELP infants, DCC was associated with increased hematocrit and better respiratory transition at birth. DCC was not associated with increased phototherapy or NICU LOS.
Quo vadis Kieferorthopädie? Digitaler Wandel und Update Kiefergelenk
Authors: Jung Britta
Published: September 2017

Sehr geehrte Kolleginnen und Kollegen!

In dieser Ausgabe möchten wir die spannenden Themenfelder „Digitaler Wandel“ und „Update Kiefergelenk“ aufgreifen.
Bronchusmanschettenresektion: aktuelle Operationstechnik und Komplikationsmanagement
Authors: Ludwig Corinna
Published: September 2017

Die Bronchusmanschettenresektion ist auch bei Patienten mit normaler Lungenfunktion ein Standardverfahren zur Resektion von Lungentumoren in zentraler Lage. Ziel dieser Methode ist es, parenchymerhaltend zu operieren und dadurch die Pneumonektomie und deren Komplikationen in Bezug auf Langzeitüberleben und Lebensqualität zu vermeiden. Mit dem Fortschreiten der minimalinvasiven Thoraxchirurgie befindet sich auch diese Operationstechnik im Wandel. Diese Arbeit setzt den Fokus auf die neuen Aspekte der Bronchusmanschettenresektion, bezugnehmend auf die Literatur.
Stereotaktische Strahlentherapie bei Lungenkrebs im Stadium I – gibt es eine Evidenz?
Authors: Guckenberger Matthias
Published: September 2017

Die körperstereotaktische Bestrahlung (SBRT) ist eine noch junge Form der Präzisionsradiotherapie, die es erlaubt, lokal begrenzte Tumoren hochdosiert und gleichzeitig schonend zu bestrahlen. Die schnelle technische Weiterentwicklung und gleichzeitig prospektiv-klinische Evaluation erfolgte intensiv beim nicht kleinzelligen Lungenkarzinom (NSCLC) im frühen Stadium. Heute ist SBRT bereits eine evidenzbasierte und die leitliniengerechte Therapie beim NSCLC im Stadium I, wenn aufgrund begleitender Komorbiditäten eine Lobektomie kontraindiziert ist. Auch älteren und komorbiden Patienten kann mittels SBRT eine kurative Therapieoption angeboten werden; nur bei äußerst begrenzter Lebenserwartung sollte darauf verzichtet werden. Obwohl immer mehr Daten auf eine Äquivalenz von Lobektomie und SBRT hinweisen, wird die SBRT bei operablen Patienten ohne Risikofaktoren meist nur dann eingesetzt, wenn der Patient eine Lobektomie ablehnt. Darüber hinaus werden aktuell zahlreiche Anwendungen der SBRT beim lokal fortgeschrittenen NSCLC und insbesondere in der Situation der Oligometastasierung und Oligoprogression klinisch und wissenschaftlich evaluiert, mit vielversprechenden Ergebnissen.
Mind the Gap! Die Körperwahrnehmung von Patienten mit Essstörungen
Authors: Junne Florian , Zipfel Stephan
Published: September 2017

„Evaluation of the disturbance in body image is of importance not only as a diagnostic criterion, but also in appraising treatment progress. Anorexic patients may gain weight for many reasons or may seem to progress well in psychotherapy. Without a corrective change in the body image, however, the improvement is apt to be only a temporary remission“.