bluuebunny/crossref_metadata_2025 huggingface dataset:
Seawater sulphate heritage governed early Late Miocene methane consumption in the long-lived Lake Pannon
Authors: Lin Zhiyong , Strauss Harald , Peckmann Jörn , Roberts Andrew P. , Lu Yang , Sun Xiaoming , Chen Tingting , Harzhauser Mathias
Published: June 2023

Sulphate deficiency makes lake environments a key source of atmospheric methane because sulphate-driven anaerobic oxidation of methane (SD-AOM) is hindered. Miocene to Pliocene Lake Pannon was the largest European lake, although the extent of its methane production remains unclear. When sulphate is available, SD-AOM occurs commonly in anoxic sediments and is recorded by authigenic iron sulphides. Here we identify abundant tubular pyrite and greigite aggregates from Lake Pannon sediments, which record brackish early lake conditions at ~11.3 Ma. The iron sulphides are morphologically similar to those reported elsewhere from methane seep and gas hydrate environments. Microscale sulphur isotope analysis and multiple sulphur isotope patterns of iron sulphides, and elevated sedimentary Ba/Al and Mo/Al ratios, are consistent with their derivation from SD-AOM under marine conditions. These results indicate substantial methane consumption in early Lake Pannon, and that sulphate was the dominant oxidant for AOM, which reduced the release of sedimentary methane to the atmosphere. SD-AOM signals archived by iron sulphides are valuable for evaluating methane consumption in lacustrine sediments.
Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery
Authors: Malek-Khatabi Atefeh , Sadat Razavi Malihe , Abdollahi Alyeh , Rahimzadeghan Milad , Moammeri Fatemeh , Sheikhi Mojgan , Tavakoli Mohamadreza , Rad-Malekshahi Mazda , Faraji Rad Zahra
Published: June 2023

Different types of Microneedles (MNs) used in drug, vitamin, protein and vaccine delivery.
NOx reduction against sulfur poisoning by using Ce-modified Cu-SAPO-34 catalysts
Authors: Ge Liumei , Wang Aiyong , Hu Xiaonan , Zhang Jin , He Jiebing , Wang Penglu , Han Lupeng , Zhang Dengsong
Published: June 2023

NOx reduction against sulfur poisoning was demonstrated by using Ce-modified Cu-SAPO-34 catalysts.
Photocatalytic CO2 reduction with a TiO2-supported copper photosensitizer and an iron-based CO2 reduction catalyst
Authors: Huerta-Zerón H. D. , Rockstroh N. , Lang M. , Surkus A.-E. , Brüser V. , Lochbrunner S. , Junge H. , Beller M.
Published: June 2023

Selective photocatalytic carbon dioxide reduction to carbon monoxide is achieved employing a supported photosensitizer in combination with an iron catalyst. The composite material showed a better performance than the purely homogeneous system.
Photoelectrochemical C–H activation of methane to methyl radical at room temperature
Authors: Amano Fumiaki , Shintani Ayami , Sakakura Tatsuya , Takatsuji Yoshiyuki , Haruyama Tetsuya
Published: June 2023

Visible light illumination induced CH4oxidation over a WO3photoanode. The production of C2H6implies the formation of methyl radicals through photoelectrochemical activation of methane.
Effects of the probioticBacillus coagulansBC69 on the metabolic and histological alterations induced by a high-sugar and high-fat diet in C57BL/6J mice
Authors: Huang Jiawei , Jiang Rumeng , Wang Yonghong
Published: June 2023

Bacillus coagulansBC69 alleviates the metabolic disorders and intestinal flora dysbiosis caused by a high-sugar and high-fat diet.
A tetracyclic-bislactone-based copolymer donor for efficient semitransparent organic photovoltaics
Authors: Li Mingjie , An Tai , Ou Zongliang , Jin Ke , Jin Zhiwen , Yan Keyou , Tian He , Wang Wentao , Yang Shangfeng , Wang Guan-Wu , Song Qiuling , Xiao Zuo , Ding Liming
Published: June 2023

A copolymer donor PBDTTPTP based on a tetracyclic bislactone unit achieved a high light utilization efficiency of 4.38% in semitransparent organic photovoltaics.
Removal of methyl red from wastewater using a NiO@Hyphaene thebaicaseed-derived porous carbon adsorbent: kinetics and isotherm studies
Authors: Ahmed Abdelaal S. A. , Sanad Moustafa M. S. , Kotb Ahmed , Negm Ahmed N. R. M. , Abdallah Mohamed H.
Published: June 2023

In this study, the adsorption of methyl red (MR) dye from wastewater on nickel oxide (NiO) doped in porous carbon derived fromHyphaene thebaica(HT) seeds (NiO@HT derived C) as an adsorbent material was investigated.
Redox double-switch cancer theranostics through Pt(iv) functionalised manganese dioxide nanostructures
Authors: Brito Beatriz , Ruggiero Maria Rosaria , Price Thomas W. , da Costa Silva Milene , Genicio Núria , Wilson Annah J. , Tyurina Olga , Rosecker Veronika , Eykyn Thomas R. , Bañobre-López Manuel , Stasiuk Graeme J. , Gallo Juan
Published: June 2023

A new redox-responsive double-switch cancer theranostic was developed based on Mn nanostructures and a Pt prodrug. The ability of these probes to respond to altered redox states was validated in 2/3D cell models and in a preclinical mouse model.
Uniform nucleation and growth of Cs3Cu2I5nanocrystals with high luminous efficiency and structural stability and their application in white light-emitting diodes
Authors: Liu Zirui , Li Wei , Wang Lin , Zhang Fei , Wang Sheng , Liu Junchuan , Zhang Chengxi , Yin Luqiao , Jia Guohua , Shi Zhifeng , Yang Xuyong
Published: June 2023

Copper-based ternary halide composites have attracted great attention due to their superior chemical stability and optical properties.
The role of lanthanide luminescence in advancing technology
Authors: Tessitore Gabriella , Mandl Gabrielle A. , Maurizio Steven L. , Kaur Mannu , Capobianco John A.
Published: June 2023

This review provides a historical overview of the role of lanthanide luminescence in scientific advancements that have enabled past, current, and future commercial technologies.
Nano-biosensor for SARS-CoV-2/COVID-19 detection: methods, mechanism and interface design
Authors: Liu Yansheng , Qin Zhenle , Zhou Jin , Jia Xiaobo , Li Hongli , Wang Xiaohong , Chen Yating , Sun Zijun , He Xiong , Li Hongda , Wang Guofu , Chang Haixin
Published: June 2023

Biosensors based on surface techniques, combined with the advantage of physical/chemical mechanisms, demonstrate great potential in detecting Covid-19/SARS-CoV-2.
Preparation of quasi-core/shell structured composite energetic materials to improve combustion performance
Authors: Wang Ruihao , Yang Lanting , Zhang Zhenwei , Song Wenkui , Wang Dunju , Guo Changping
Published: June 2023

The pRDX@PTFE–Al quasi-core/shell structured high-energy explosives were prepared and found to possess superior combustion and mechanical sensitivity properties.
A translationally active ligand based on a [2]rotaxane molecular shuttle with a 2,2′-bipyridyl core
Authors: Dhara Ayan , Dmitrienko Anton , Hussein Rahaf N. , Sotomayor Ariel , Wilson Benjamin H. , Loeb Stephen J.
Published: June 2023

A [2]rotaxane molecular shuttle with a central bipy unit can coordinate to Pt(ii) or Zn(ii), but only the octahedral geometry facilitated by the Zn(ii) centre can mediate translational motion of the interlocked crown ether along the axle.
Construction of pyrroles, furans and thiophenes via intramolecular cascade desulfonylative/dehydrogenative cyclization of vinylidenecyclopropanes induced by NXS (X = I or Br)
Authors: Meng Zhe , Yan Jun , Ning Chao , Shi Min , Wei Yin
Published: June 2023

Pyrroles, furans, and thiophenes were efficiently obtained by NXS mediated desulfonylative/dehydrogenative cyclization of vinylidenecyclopropanes within 0.5 h. The reaction mechanism was investigated by control experiments and DFT calculations.
Enantioselective synthesis of hydantoins by chiral acid-catalysed condensation of glyoxals and ureas
Authors: Aryal Sushant , Hone Christopher A. , Polson Matthew I. J. , Foley Daniel J.
Published: June 2023

The paper describes the enantioselective synthesis of 5-monosubstituted hydantoinsviachiral phosphoric acid-catalysed condensation of glyoxals and ureas at room temperature.
Thermal properties and phase transition behaviors of possible caloric materials Bi0.95Ln0.05NiO3
Authors: Chen Chen , Kosugi Yoshihisa , Goto Masato , Shimakawa Yuichi
Published: June 2023

The magnetic transition occurred at a temperature lower than the charge-transfer-transition temperature in Bi0.95Ln0.05NiO3 and the magnetic entropy change did not contribute to the latent heat produced by the intersite-charge-transfer transition.
Obtaining a broadband magneto-mechano-electric generator with large power for IoT operation
Authors: Patil Deepak R. , Lee Seungah , Thakre Atul , Kumar Ajeet , Jeong Dae-Yong , Ryu Jungho
Published: June 2023

The strong interaction between the MME generator and MFC resulted in a wide bandwidth of 57–61.5 Hz while maintaining a large power under different magnetic fields.
In situhierarchical pore engineering in small pore zeoliteviamethanol-mediated NH4F etching
Authors: Xing Youdong , Li Guangchao , Lin Zezhou , Xu Zhihang , Huang Haitao , Zhu Ye , Tsang Shik Chi Edman , Li Molly Meng-Jung
Published: June 2023

Hydrolysis-activatedin situpore engineering in zeolites: NH4F in methanol as a deceptively inert agent for a Trojan horse-like introduction and activation.
Spontaneous adsorption–oxidation of gaseous elemental mercury via a conjugated unit –NH+˙–Cl*: creation and mechanisms
Authors: Ma Zhao , Hao Runlong , Liu Tianxin , Li Hongming , Yang Jianping , Zeng Zefeng , Yuan Bo , Qi Meng , Wang Lidong
Published: June 2023

A Cl-doped protonated polyaniline-coated multiwall carbon nanotube (Cl-PANI+@MWCNT) composite provides a new method for the spontaneous adsorption–oxidation of gaseous elemental mercury.
Bioinspired topological design with unidirectional water transfer for efficient atmospheric water harvesting
Authors: Bu Yiming , Li Xin , Lei Weiwei , Su Hongli , Yang Hongjun , Xu Weilin , Li Jingliang
Published: June 2023

A sodium alginate-based hemisphere with centripetal conical channels loaded with CaCl2 crystals and coated with a photothermal layer was designed for moisture absorption, unidirectional water transfer and solar-driven water evaporation.
Synthesis of 3C/2H/6H heterojunction SiC nanowires with high-performance supercapacitors by thermal evaporation
Authors: Kang Pengchao , Zhao Qiqi , Zhang Tien , Xue Wei , Qian Jinrui , Wei Zengyan , Wang Pingping , Wu Gaohui
Published: June 2023

A novel approach enhances the energy storage of SiC NWs, a promising electrode material. It exhibits a specific capacitance of 227.8 F g−1 and 90.12% cycling stability after 10 000 cycles.
A narrow-bandgap photothermal material based on a donor–acceptor structure for the solar–thermal conversion application
Authors: Zhang Ruoyu , Jin Nanxi , Jia Tao , Wang Luoqing , Liu Jing , Nan Mengmeng , Qi Shuo , Liu Siqi , Pan Yuyu
Published: June 2023

Organic photothermal materials can effectively convert solar energy into thermal energy in an environmentally friendly manner and have great potential for applications such as desalination and thermoelectric power generation.
Mechanistic insights into enhanced photocatalytic H2O2 production induced by a Z-scheme heterojunction of copper bismuth oxide and molybdenum sulfide
Authors: Tikoo Akshay , Lohia Nikitha , Charan Kondeti Sri Surya , Meduri Praveen
Published: June 2023

Photocatalytic hydrogen peroxide (H2O2) production using a Z-scheme copper bismuth oxide and molybdenum sulfide photocatalyst.
Electrospun nanofibrous membranes of recombinant human collagen type III promote cutaneous wound healing
Authors: Dong Zuqin , Liu Quanying , Han Xiaowen , Zhang Xinyue , Wang Xinyue , Hu Chen , Li Xing , Liang Jie , Chen Yafang , Fan Yujiang
Published: June 2023

Cutaneous wound healing is a complex process that strives to re-establish the original structure and functions of the skin.
Ordered porous RGO/SnO2 thin films for ultrasensitive humidity detection
Authors: Li Zhou , Gardner David W. , Xia Yong , Zhao Sikai , Pan Aifei , Goel Nishit , Bart Stephen , Liu Chen , Yi Jianxin , Carraro Carlo , Maboudian Roya
Published: June 2023

Ordered porous RGO/SnO2 thin films for ultrasensitive humidity detection at room temperature.
Anisotropic X-ray detection performance of melt-grown CsPbBr3 single crystals
Authors: Hua Yunqiu , Sun Xue , Li Xiang , Cui Fucai , Yue Zhongjie , Liu Jiaxin , Liu Hongjie , Zhang Guodong , Tao Xutang
Published: June 2023

The investigation of the anisotropic X-ray detection performance of bulk CsPbBr3 single crystals grown by the vertical Bridgman method.
Conjugated wrapping polymer influences on photoexcitation of single-walled carbon nanotube-based thin film transistors
Authors: Dallaire Nicholas J. , Mirka Brendan , Manion Joseph G. , Bodnaryk William J. , Fong Darryl , Adronov Alex , Hinzer Karin , Lessard Benoît H.
Published: June 2023

The fabrication of high-purity semiconducting single-walled carbon nanotubes (sc-SWNTs) often utilizes conjugated polymers to isolate the semiconducting from the metallic species.
Enhancement method of series hybrid ship energy efficiency for speed and energy collaborative optimization
Authors: Yuan Yupeng , Wang Xiaoyu , Tong Liang , Yuan Chengqing , Shen Boyang , Long Teng
Published: June 2023

Hybrid ships have recently garnered increasing attention as a promising solution for energy shortages and environmental pollution. However, changes in the navigation environment can greatly affect the energy efficiency of these vessels. Therefore, improving the energy efficiency of hybrid ships continues to be a key issue. Our study examined the energy efficiency of a diesel‐electric series hybrid ship operating on an inland river, and a method to optimise series hybrid ship energy efficiency was proposed. The energy consumption model, power demand model, and decision function with minimum fuel consumption as the evaluation criteria were established according to the ship's characteristics and hybrid system. By analysing the data collected from an actual ship, the operating conditions of the navigation environment were identified using the k‐means algorithm, and the total distance travelled by the ship was divided into several sub‐trajectories. Afterwards, the optimised speed of the ship and the optimised output power of each power source were determined using the grasshopper optimization algorithm. The ship's energy efficiency levels before and after using the energy efficiency enhancement method were compared and analysed, and the effects of this optimization method on the ship's energy efficiency in several typical voyages were analysed. Our findings demonstrated that this optimization method can distribute the output of the power source in a better way, thereby optimising the speed of the vessel and maintaining stable sailing. More importantly, the proposed method can reduce fuel consumption by 17.04%.
An iterative algorithm for the joint estimation of multiple targets and observation stations using direction of arrival and time difference of arrival measurements despite station position errors
Authors: Jiang Linqiang , Tang Tao , Wu Zhidong , Zhao Paihang , Zhang Ziqiang
Published: June 2023

Direction of arrival (DOA) and time difference of arrival (TDOA) hybrid localisation is an effective localisation technique. Station position errors affect localisation performance. Owing to the highly non‐linear nature of the problem, there are few methods of DOA/TDOA hybrid localisation in the presence of station position errors. Hence, an iterative constrained weighted least squares (ICWLS) algorithm is proposed to estimate locations of multiple targets and stations for DOA/TDOA hybrid localisation with station position errors. To ensure convergence to the global optimal solution, non‐convex equality constraints are approximated to linear constraints during each iteration. The weighted averaging strategy using the results of the previous iteration is used to reduce the number of iterations. Theoretical analysis and simulation results show that the ICWLS can reach the Cramér–Rao lower bound. Additionally, the performance of multiple targets is better than that of a single target. The simulation results show that the ICWLS algorithm has higher accuracy than other methods and higher localisation accuracy can be maintained when the observation stations are under an ill‐conditioned geometry.
Model-independent periodogram for scanning astrometry
Authors: Binnenfeld A. , Shahaf S. , Zucker S.
Published: June 2023

We present a new periodogram for the periodicity detection in one-dimensional time-series data from scanning astrometry space missions such as HIPPARCOS or Gaia. The periodogram is non-parametric and does not rely on a full or approximate orbital solution. Since no specific properties of the periodic signal are assumed, the method is expected to be suitable for the detection of various types of periodic phenomena, from highly eccentric orbits to periodic variability-induced movers. The periodogram is an extension of the phase-distance correlation periodogram we introduced in previous papers based on the statistical concept of distance correlation. We demonstrate the performance of the periodogram using publicly available HIPPARCOS data, as well as simulated data. We also discuss its applicability for Gaia epoch astrometry that is to be published in the future data release 4.
Simulation and Analyses of Turbulent Flow in Different Phases of Stenosed Renal Artery
Authors: Zia Zahra , Ami Faisal , Hussain Mudasir , ur Rehman Zia , Arzak Semab Shahazadi
Published: June 2023

This study concerns the two-dimensional structure computational results of renal artery stenosis. In this paper, the turbulent flow of the stenosed vessel is stimulated and correlates the different stages of stenosis with each other. As we know that the blood flow in most blood vessels is laminar, but in case of stenosed vessel, the blood flow becomes turbulent; this is due to the blockage that blood does not flow linearly and produces chaos. Several liquid parameters are analyzed, such as pressure, velocity, turbulence kinetic energy, density, and shear rate. The inlet and outlet flow are especially concerning. For this purpose, we explored the stenosed behavior by the software COMSOL Multiphysics which provided us with a complete examination of the Computational fluid dynamics. With an increase in renal artery stenosis, there is a decrease in the blood flow which will automatically affect the pressure of the blood and can cause serious kidney diseases and, in some cases, permanent damage to the kidney sometimes. This paper highlights the early stages of renal artery stenosis, which are likely to be cured. Also, it shows the behavior of the severe late stages, which we consider nearly impossible to cure. The result explains that how different parameters vary according to stated cases.
Mechanical Design and Fabrication of a Data Buoy
Authors: Mir Hafsa
Published: June 2023

A data buoy for measuring coastal wave-action has been designed and constructed. The buoy is essentially a 0.6 m diameter sphere that is made of fiber-glass with aluminum, steel and polymer parts. While the overall geometry of the buoy is superficially similar to that of existing commercial spherical buoys (e.g. Wave-Rider by Datawell), the present design is based on a simple robust structure and mass-market electronics. A significant dual-use feature of this design is that the structure is usable as a float in a wave-energy generation device. This is possible due to the essentially isolated central structure and an electronics enclosure that is sealed both from the external environment and from the bulk shell of the buoy. This also allows the electronics to be mounted in an easily- modified, rack configuration that can be removed from the buoy shell. In a wave-energy generation set-up the electronics rack would be removed and the central cylinder will become part of a linear-motion type generator, with at least +/- 25 cm of internal movement available to it that is waterproof (for near surface or shallow immersions). Alternatively, for large wave motions, the buoy can couple to an energy-generating device using flanges that mate with its bolt circle pattern. However, at the moment, the buoy enclosure is dedicated to wave-action measurement, i.e., a data buoy with an onboard inertial measurement unit (IMU) and a radio-link to send real-time data to a receiving unit that can be on a boat or at the seashore. Basic GPS data are also transmitted. This is of interest if the buoy is being deployed in a drifting (un-moored) mode. This paper will only discuss the mechanical design and fabrication of the structure.
Neuro-Ophthalmic Visual Impairment in the Setting of COVID-19
Authors: Dinkin Marc , Sathi Swetha
Published: June 2023

We set out to describe in detail the afferent neuro-ophthalmological complications that have been reported in association with coronavirus disease 2019 (COVID-19) infection. We describe and elaborate on mechanisms of disease, including para-infectious inflammation, hypercoagulability, endothelial damage, and direct neurotropic viral invasion. Despite global vaccination programs, new variants of COVID-19 continue to pose an international threat, and patients with rare neuro-ophthalmic complications are likely to continue to present for care.

Afferent complications from COVID-19 include homonymous visual field loss, with or without higher cortical visual syndromes, resulting from stroke, intracerebral hemorrhage, or posterior reversible leukoencephalopathy. Optic neuritis has frequently been reported, sometimes along with acute disseminated encephalomyelopathy, often in association with either myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) or less commonly aquaporin-4 seropositivity or in newly diagnosed multiple sclerosis. Ischemic optic neuropathy has rarely been reported. Papilledema, resulting either from venous sinus thrombosis or idiopathic intracranial hypertension in the setting of COVID-19, has also been described.

Observed afferent neuro-ophthalmic associations need to be confirmed though larger comparative studies. Meanwhile, the range of possible complications should be recognized by neurologists and ophthalmologists alike, to facilitate faster diagnosis and treatment of both COVID-19 and its neuro-ophthalmic manifestations.
Streptococcus constellatus-Induced Blindness in a 10-Year-Old Boy: A Case Report
Authors: Wang Sixuan , Dou Zhenzhen , Feng Wenya , Hu Bing , Cui Yanhui , Yang Xiaojian , Li Li , Ge Wentong , Liu Gang
Published: June 2023

In this article, we report a 10-year-old boy with acute bacteremia and left eye blindness. Culture from abscess drainage was positive for Streptococcus constellatus. Infection caused by S. constellatus is rare among children, and to our knowledge, this is the first report of this pathogen causing blindness. The rapidness of progression in this case is alarming. We also summarize other cases of S. constellatus infection.
In Vitro Susceptibility of Burkholderia pseudomallei Isolates to Cefiderocol and Ceftazidime/Avibactam from Odisha, India
Authors: Jena Jayanti , Behera Bijayini , Nayak Gayatree , Mohanty Srujana , Mahapatra Ashoka , Purushotham Prashanth , Radhakrishnan Anjuna , Tripathy Manaswiny
Published: June 2023

Introduction and Objectives The availability of a limited arsenal of antibacterial agents effective against Burkholderia pseudomallei, the causative agent of melioidosis, together with sporadic reports of emergence of resistance necessitates an evaluation of in vitro activity of new antimicrobials against clinical B. pseudomallei isolates. Cefiderocol (CFDC), a novel siderophore cephalosporin, and ceftazidime-avibactam (CZA), a new β lactam combination agent, have shown promising results for the treatment of difficult-to-treat Gram-negative bacilli infections with limited treatment options. This study was conducted to determine the in vitro activity of CFDC and CZA against a contemporary collection of 60 B. pseudomallei clinical isolates.

Materials and Methods Minimum inhibitory concentrations (MIC) of CFDC and CZA were determined by broth microdilution and E-test, respectively. The performance of disk diffusion was also evaluated for CFDC.

Results All B. pseudomallei isolates were susceptible to CFDC and CZA with MIC range of 0.125 to 2 mg/L and 0.19 to 1 mg/L, respectively. Zone diameters for CFDC ranged from 31 to 40 mm.

Conclusion CFDC and CZA exhibited excellent in vitro activity against 60 B. pseudomallei isolates. Further pharmacokinetic-pharmacodynamics studies and clinical trials are needed to prove the clinical efficacy of CFDC and CZA in the treatment of melioidosis.
Arm Length—Does It Influence Late Response in a Nerve Conduction Study?
Authors: G.R Sathya , Arulneyam Jayanthi , J. Venkatachalam , Manikandan M.
Published: June 2023

Introduction F wave response, a late response obtained from a motor nerve, can be influenced by various external factors like gender, temperature, height, weight, and limb length, and hence it causes variation in the measured parameters. Since very few studies have studied the impact of arm length on the F wave, this study was conducted to analyze the relation between the arm length on various parameters of F wave and hence to consider the importance of it during conduct of a nerve conduction study.

Methods The study was conducted among 40 healthy individuals and 40 diabetics with neuropathy. The arm length was measured in the upper limbs in both the groups and F wave was recorded following a conventional procedure using a standardized instrument.

Results This study showed that in the upper limbs of both the groups, there existed a positive correlation for certain parameters like minimum, maximum and mean latencies, persistence, FM latency and M latency, and a negative correlation for chronodispersion.

Conclusion F wave parameters should be adjusted for arm length to improve the sensitivity and diagnostic ability of neurological testing.
Science teachers’ collaborative innovative activities: the role of professional development and professional experience
Authors: Pečiuliauskienė Palmira , Kaminskienė Lina , Lehtinen Erno
Published: June 2023

Despite the significant research interest in teachers’ innovative activities, the role of work experience and professional development (PD) as predictors of science teachers’ innovative work behaviour has rarely been studied. By using the TIMSS 2015 data of three countries with different levels of student achievements in science (Japan, Lithuania and South Africa), this article focuses on revealing how PD content, duration and teaching experience predict science teachers’ two collaborative innovative activities: working together to try out new ideas and sharing new ideas. According to Rogers’ diffusion theory, these two activities correspond to the fourth and fifth stages of innovation: implementation and sharing. The results of an ordinal regression analysis revealed that PD duration could not predict the collaborative innovative activity of science teachers and that teaching experience was a significant predictor of collaborative innovative activity only among Japanese teachers. The study showed that in Lithuanian and South African samples, PD focusing on pedagogical content knowledge, such as science curriculum, students’ critical thinking and enquiry skills and addressing individual students’ needs, positively predicted teachers’ innovative activities. The study invites future research and discussion about the role of PD duration in the collaborative innovative activity of science teachers.
Super-resolution imaging based on cleanable, controllable, and convenient microdroplet generation
Authors: Lim Alane
Published: June 2023

Technology uses optical tweezers and microdroplets as an alternative approach to high-resolution imaging.
Numerical simulation and investigation of ultra-short pulse laser ablation on Ti6Al4V and stainless steel
Authors: Peng Li , Li Mingqiang , Wang Pei , Li Xiaoguang , Zhang Yangguang , He Minqing , Zhou Cangtao , Zhang Hua , Chen Shi
Published: June 2023

In ultra-short pulse laser machining and micro/surface processing, accurate simulation of laser ablation is important for understanding laser-target interaction and improving ablation performance, but it remains challenging. This work aims to develop a numerical model to improve the accuracy of the ablation depth calculation. A grid deformation scheme is proposed based on energy conservation and considering contributions to instant material removal from both the electron and lattice subsystems. By incorporating this scheme with the two-temperature model (TTM), a reasonable prediction of the instant target surface profile during laser ablation has been achieved. In the case of single-pulse femtosecond laser ablation of Ti6Al4V, the calculated ablation depth ranges from 0.06 to 0.56 μm for laser energy from 1.0 to 10.0 μJ. For single-pulse picosecond laser ablation of stainless steel, as laser energy increases from 6.0 to 18.5 μJ, the predicted ablation crater deepens accordingly from 40 to 87 nm. In addition, for multi-pulse picosecond laser ablation of stainless steel, a linear dependence of the ablation depth on the pulse number is observed up to a depth of about 803 nm at 6.0 μJ and 20 pulses. In all the above-mentioned cases, the calculation results are in better agreement with experimental measurements than conventional TTM or other material removal schemes, validating the accuracy of the proposed model.
Microbiological indicators as sensitive indicators in the assessment of areas contaminated by heavy metals
Authors: Melloni Eliane Guimarães Pereira , Melloni Rogério , Pastor-Jáuregui Rocío , Aguilar-Garrido Antonio , Martín-Peinado Francisco José
Published: June 2023

Context As one of the world’s largest mining spills, the Aznalcóllar pyrite mine accident in Spain in 1998 resulted in ~45 km2 of agricultural soils polluted by arsenic and heavy metals. The Guadiamar Green Corridor (GGC) helped with soil remediation but residual pollution is still detected 20 years later. Aims Several methodologies based on chemical indicators have been used to assess the recovery of these areas. However, simple microbiological indicators (e.g. microbial activity and biomass, and metabolic quotient (qCO2)) are yet to be uesed. The aim of this study was to evaluate areas contaminated by arsenic and heavy metals using microbiological indicators of soil quality. Methods We used a systematic random sampling design to collect soil samples from two soil groups with different recovery trajectories. We analysed the total and water-soluble concentrations of arsenic (As), lead (Pb), copper (Cu), and zinc (Zn), the main soil properties, and bioassays including microbial activity and biomass, and metabolic quotient or microbial stress (qCO2). Key results Twenty years after the accident, soils with As and Pb concentrations that consistently exceeded regulatory levels had altered soil microbial biomass and functioning. Although overall rates of microbial respiration were not significantly different between polluted soils, microbial biomass was lower and qCO2 was higher in the more polluted than in less polluted soils. Conclusions The metabolic quotient and microbial biomass are sensitive indicators in the monitoring over time of soil polluted by arsenic and heavy metals. Implications Microbial indicators must be considered in the assessment of potential ecotoxicity and in the evaluation of soil biological properties influencing soil recovery in the long term.
Bullous pemphigoid and Graves' disease: an association between skin and thyroid autoimmunity
Authors: Fiorucci MC , Cozzani E , Casu M , Murialdo G , Parodi A , Rebora A.
Published: June 2023

No abstract available
Treatment of molluscum contagiosum with topical diphencyprone therapy
Authors: Kang SH , Lee D , Hoon Park , Cho SH , Lee SS , Park SW.
Published: June 2023

No abstract available
Referral pattern of skin diseases in an acute outpatient dermatological clinic in Copenhagen
Authors: Kiellberg Larsen , Sand C.
Published: June 2023

The referral pattern of acute dermatologic conditions is not well described in either outpatients or hospitalized patients. The aim of this study is to describe in more detail the skin diseases that were referred for evaluation in an acute outpatient clinic at Bispebjerg Hospital, Copenhagen. In a 3-month period in 2003 a total of 428 consecutive new patients were referred for various skin diseases that needed subacute and acute dermatological evaluation in a university hospital setting. Referral pattern, age ratio and sex ratio were examined retrospectively. Two hundred and twenty-five (53%) of the 428 patients were referred from other hospital clinics in the local area. Sixty-six (15%) were referred from private practising dermatologists and 64 (15%) from general practitioners in the City of Copenhagen. Referral information was not noted in 35 (8%) of the 428 patients. The most prevalent diagnoses were: unspecified eczema (10.7%), drug eruptions (6.3 %), psoriasis (6.3%), atopic dermatitis (5.6%), bacterial skin infections (4.0%), inflammatory skin disorders (3.7%), seborrhoeic dermatitis (3.5%), urticaria (3.0%), seborrhoeic keratosis (3.0%), toxic contact dermatitis (2.8%), ulcus cruris (2.8%), autoimmune diseases (2.8%), malignant skin tumours (2.5%), candidiasis (2.5%), pruritus/prurigo (2.5%) and viral skin infections (2.5%). The fact that drug eruptions are one of the leading causes of acute referral conditions probably reflects the proximity to other hospital settings, where a large number of patients receive several systemic medicaments for various conditions.
Premalignant nature of oral lichen planus
Authors: Laeijendecker R , Van Joost , Kuizinga MC , Tank B , Neumann HA.
Published: June 2023

The issue as to whether oral lichen planus is a premalignant disorder is still controversial. This study aimed to examine oral malignancies associated with oral lichen planus and to investigate whether oral lichen planus has an intrinsic malignant potential or whether there are also contributing external risk factors. A retrospective cohort study in 200 Caucasian patients with oral lichen planus was conducted between 1991 and 2003. Aspects such as sex, age, clinical variant, affected anatomical sites, duration of the disease, histopathology, prior immunosuppressive treatment, exposure to potential carcinogens and other concomitant diseases were examined. Histopathological examination was repeated during the follow-up if a malignancy was suspected. Three (1.5%) of the 200 patients developed an oral squamous cell carcinoma at the same site following the initial diagnosis of oral lichen planus after a period of 3-6 years (mean 4.3 years). Contributing external risk factors were also noted in two of the three patients (smoking for 20 years and systemic immunosuppressive treatment for 2 years). The exact incidence of malignant transformation is difficult to establish, because of the low number of patients and because of the possible contribution of external risk factors, which may be relevant in oral malignancy.
Global well-posedness for 2D fractional inhomogeneous Navier–Stokes equations with rough density
Authors: Li Yatao , Miao Qianyun , Xue Liutang
Published: June 2023

This paper is concerned with the global well-posedness issue of the two-dimensional (2D) incompressible inhomogeneous Navier–Stokes equations with fractional dissipation and rough density. By establishing the

L
t
q

(

L
x
p

)

-maximal regularity estimate for the generalized Stokes system and using the Lagrangian approach, we prove the global existence and uniqueness of regular solutions for the 2D fractional inhomogeneous Navier–Stokes equations with large velocity field, provided that the initial density is sufficiently close to the constant 1 in

L
2

∩

L
∞

and in the norm of some multiplier spaces. Moreover, we also consider the associated density patch problem, and show the global persistence of

C

1
,
γ

-regularity of the density patch boundary when the piecewise jump of density is small enough.
On global dynamics of type-K competitive Kolmogorov differential systems
Authors: Hou Zhanyuan
Published: June 2023

This paper deals with global asymptotic behaviour of the dynamics for N-dimensional type-K competitive Kolmogorov systems of differential equations defined in the first orthant. It is known that the backward dynamics of such systems is type-K monotone. Assuming the system is dissipative and the origin is a repeller, it is proved that there exists a compact invariant set Σ which separates the basin of repulsion of the origin and the basin of repulsion of infinity and attracts all the non-trivial orbits. There are two closed sets S

H
and S

V
, their restriction to the interior of the first orthant are

(
N
−
1
)

-dimensional hypersurfaces, such that the asymptotic dynamics of the type-K system in the first orthant can be described by a system on either S

H
or S

V
: each trajectory in the interior of the first orthant is asymptotic to one in S

H
and one in S

V
. Geometric and asymptotic features of the global attractor Σ are investigated. It is proved that the partition

Σ
=

Σ
H

∪

Σ
0

∪

Σ
V

holds such that

Σ
H

∪

Σ
0

⊂

S
H

and

Σ
V

∪

Σ
0

⊂

S
V

. Thus, Σ0 contains all the ω-limit sets for all interior trajectories of any type-K subsystems and the closure

Σ
H

∪

Σ
V

‾

as a subset of Σ is invariant and the upper boundary of the basin of repulsion of the origin. This Σ has the same asymptotic feature as the modified carrying simplex for a competitive system: every nontrivial trajectory below Σ is asymptotic to one in Σ and the ω-limit set is in Σ for every other nontrivial trajectory.
Spontaneous isospin polarization and quantum Hall ferromagnetism in a rhombohedral trilayer graphene superlattice
Authors: Han 韩 Xiangyan 香岩 , Liu 刘 Qianling 倩伶 , Niu 牛 Ruirui 锐锐 , Qu 曲 Zhuangzhuang 壮壮 , Wang 王 Zhiyu 知雨 , Li 李 Zhuoxian 卓贤 , Han 韩 Chunrui 春蕊 , Watanabe Kenji , Taniguchi Takashi , Gan 甘 Zizhao 子钊 , Lu 路 Jianming 建明
Published: June 2023

Moiré superlattices in van der Waals heterostructures have recently attracted enormous interests, due to the highly controllable electronic correlation that gives rise to superconductivity, ferromagnetism, and nontrivial topological properties. To gain a deep understanding of such exotic properties, it is essential to clarify the broken symmetry between spin and valley flavors which universally exists in these ground states. Here in a rhombohedral trilayer graphene crystallographically aligned with a hexagonal boron nitride, we report various kinds of symmetry-breaking transition tuned by displacement fields (D) and magnetic fields: (i) While it is well known that a finite D can enhance correlation to result in correlated insulators at fractional fillings of a flat band, we find the correlation gap emerges before the flavor is fully filled at a positive D, but the sequence is reversed at a negative D. (ii) Around zero D, electronic correlation can be invoked by narrow Landau levels, leading to quantum Hall ferromagnetism that lifts all the degeneracies including not only spin and valley but also orbital degrees of freedom. Our result unveils the complication of transitions between symmetry-breaking phases, shedding light on the mechanisms of various exotic phenomena in strongly correlated systems.
Two non-perturbative α' or loop corrected string cosmological solutions*
Authors: Song Li , Chen Deyou
Published: June 2023

In this paper, we present two non-perturbative string cosmological solutions without curvature singularities for the bosonic gravi-dilaton system. These solutions are general in that they can straightforwardly match the perturbative solution to arbitrarily high orders in the perturbative region. The first solution includes non-perturbative

corrections based on Hohm-Zwiebach action. We then use the simple phenomenological map between the

and loop corrected theories in string cosmology to construct a non-perturbative loop corrected non-singular solution. Both solutions are non-singular everywhere. Therefore, the pre- and post-big-bangs are smoothly connected by these solutions.
Catastrophes of Cylindrical Shell
Authors: Gromov Vasilii
Published: June 2023

The present paper studies a set of bifurcation paths for a cylindrical shell under external pressure and under axial compression. For both cases, catastrophe theory methods apply; for cylindrical shell subjected to external pressure, buckling fits the wigwam catastrophe; for axially-compressed cylindrical shell, a set of post-buckling solutions does not fit a single catastrophe manifold, but rather comprises a number of high-order umbilical catastrophes. For the first case, five essential parameters, that is parameters that determine buckling load and mode, were revealed.
Ensemble deep learning of embeddings for clustering multimodal single-cell omics data
Authors: Yu Lijia , Liu Chunlei , Yang Jean Yee Hwa , Yang Pengyi
Published: June 2023

Motivation

Recent advances in multimodal single-cell omics technologies enable multiple modalities of molecular attributes, such as gene expression, chromatin accessibility, and protein abundance, to be profiled simultaneously at a global level in individual cells. While the increasing availability of multiple data modalities is expected to provide a more accurate clustering and characterization of cells, the development of computational methods that are capable of extracting information embedded across data modalities is still in its infancy.

Results

We propose SnapCCESS for clustering cells by integrating data modalities in multimodal single-cell omics data using an unsupervised ensemble deep learning framework. By creating snapshots of embeddings of multimodality using variational autoencoders, SnapCCESS can be coupled with various clustering algorithms for generating consensus clustering of cells. We applied SnapCCESS with several clustering algorithms to various datasets generated from popular multimodal single-cell omics technologies. Our results demonstrate that SnapCCESS is effective and more efficient than conventional ensemble deep learning-based clustering methods and outperforms other state-of-the-art multimodal embedding generation methods in integrating data modalities for clustering cells. The improved clustering of cells from SnapCCESS will pave the way for more accurate characterization of cell identity and types, an essential step for various downstream analyses of multimodal single-cell omics data.

Availability and implementation

SnapCCESS is implemented as a Python package and is freely available from https://github.com/PYangLab/SnapCCESS under the open-source license of GPL-3. The data used in this study are publicly available (see section ‘Data availability’).
Effects of magnet shapes on total harmonic distortion and cogging torque in a permanent magnet synchronous generator for wind turbines
Authors: Kurt Erol , Dalcalı Adem
Published: June 2023

This paper explores and theoretically reports the effects of different magnet structures on the cogging torque and the total harmonic distortion of the output waveforms from a permanent magnet generator. The generator is a radial flux machine and four different structures are considered for the magnet arrangement in the rotor component and modelled in the Ansys/Maxwell electromagnetic simulation program. This three-phase machine exhibits different behaviours towards various magnet structures, i.e. rectangular, inclined slotted rectangular, skewed double rectangular and inclined slotted skewed double rectangular, respectively. It has been proven by finite element analysis and Fourier analysis that both the cogging and total harmonic distortion values vary significantly for all models. The cogging torque values change in the range of 89.95 to 436.75 mNm and the lowest cogging torque is measured for the inclined slotted skewed double rectangular magnet geometry, while the conventional rectangular magnet geometry yields the worst value with 436.75 mNm. Furthermore, the total harmonic distortion values varies between 1.63 and 3.55 for different magnetic orientations. While the worst total harmonic distortion value is obtained from the inclined slotted rectangular magnet, the best total harmonic distortion is acquired from the skewed double rectangular magnet. All these results will provide scientists and engineers with important information in order to obtain more efficient machines.
Development of A Liquid-Phase Microextraction Method for Simultaneous Determination of Parabens in Lipstick Samples at Trace Levels by High-Performance Liquid Chromatography
Authors: Gösterişli Tuğçe U , Kublay İrem Z , Keyf Seyfullah , Bakırdere Sezgin
Published: June 2023

The endocrine-disrupting potential of parabens, as well as their relation to cancer, has sparked significant discussions over their impact. Consequently, analyses of cosmetic products are an essential necessity, particularly in terms of human health and safety. In this study, a highly accurate and sensitive liquid-phase-based microextraction method was developed to determine the five parabens at trace levels by high-performance liquid chromatography. All prominent parameters of the method such as extraction solvent type and amount (1,2-dichloroethane/250 μL), and dispersive solvent type and amount (isopropyl alcohol/2.0 mL) were optimized to enhance the extraction efficiency of the analytes. The mobile phase consisting of 50 mM ammonium formate aqueous solution (pH 4.0) and acetonitrile (60:40, v/v) was used to elute the analytes at a flow rate of 1.2 mL min−1 in the isocratic mode. Analytical performance of the optimum method for methyl, ethyl, propyl, butyl and benzyl parabens were determined and the analytes recorded detection limit values of 0.78, 0.75, 0.34, 0.33 and 0.75 μg kg−1, respectively. Four different lipstick samples were analyzed under optimum conditions of the developed method, and the amount of parabens quantified in the samples using matrix matched calibration standards was in the range of 0.11–1.03%.
Primary prophylaxis of invasive fungal diseases in patients with haematological malignancies: 2022 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)
Authors: Stemler Jannik , Mellinghoff Sibylle C , Khodamoradi Yascha , Sprute Rosanne , Classen Annika Y , Zapke Sonja E , Hoenigl Martin , Krause Robert , Schmidt-Hieber Martin , Heinz Werner J , Klein Michael , Koehler Philipp , Liss Blasius , Koldehoff Michael , Buhl Christoph , Penack Olaf , Maschmeyer Georg , Schalk Enrico , Lass-Flörl Cornelia , Karthaus Meinolf , Ruhnke Markus , Cornely Oliver A , Teschner Daniel
Published: June 2023

Patients with haematological malignancies (HM) are at high risk of developing invasive fungal disease (IFD) with high morbidity and attributable mortality. We reviewed data published until September 2021 to update the 2017 antifungal prophylaxis recommendations of the German Society of Haematology and Medical Oncology (DGHO). The strong recommendation to administer antifungal prophylaxis in patients with HM with long-lasting neutropenia, i.e. <500 cells/μL for >7 days remains unchanged. Posaconazole remains the drug of choice for mould-active prophylaxis in these patients. Novel treatment options in HM, such as CAR-T-cell treatment or novel targeted therapies for acute myeloid leukaemia (AML) were considered, however, data are insufficient to give general recommendations for routine antifungal prophylaxis in these patients. Major changes regarding specific recommendations compared to the 2017 edition are the now moderate instead of mild support for the recommendations of isavuconazole and voriconazole. Furthermore, published evidence on micafungin allows recommending it at moderate strength for its use in HM. For the first time we included recommendations for non-pharmaceutical measures regarding IFD, comprising the use of high-efficiency particulate air (HEPA) filters, smoking, measures during construction work and neutropenic diets.

We reviewed the impact of antifungal prophylaxis with triazoles on drug–drug interactions with novel targeted therapies that are metabolized via cytochrome p450 where triazoles inhibit CYP3A4/5. The working group recommends reducing the dose of venetoclax when used concomitantly with strong CYP3A4 inhibiting antifungals. Furthermore, we reviewed data on the prophylactic use of novel antifungal agents. Currently there is no evidence to support their use in a prophylactic setting in clinical practice.