bluuebunny/crossref_metadata_2025 huggingface dataset:
Paper-based analytical device for point-of-care nucleic acid quantification combining CRISPR/Cas12a and a personal glucose meter
Authors: Tanifuji Yohei , Tong Guodong , Hiruta Yuki , Citterio Daniel
Published: July 2024

Combining a CR1SPR/Cas12a assay integrated into a paper-based analytical device with a personal glucose meter signal readout results in a "sample-in–answer-out" nucleic acid quantification system.
A CRISPR/Cas12a-based fluorescence method for the amplified detection of total antioxidant capacity
Authors: Wu Qi , Xie Longyingzi , Ma Lanrui , Long Xinqi , Liu Lei , Chen Aihua , Cui Yongliang , Zhang Yaohai , He Yue
Published: July 2024

The reduction of MnO2 nanosheets by antioxidants generates abundant Mn2+, which enhances the trans-cleavage activity of CRISPR/Cas12a. A fluorescence-enhanced method was developed to measure the total antioxidant capacity.
Correction: Self-assembled methodologies for the construction of DNA nanostructures and biological applications
Authors: Ye Rui , Wang Yuqi , Liu Yan , Cai Ping , Song Jie
Published: July 2024

Correction for ‘Self-assembled methodologies for the construction of DNA nanostructures and biological applications’ by Rui Ye et al., Biomater. Sci., 2024, https://doi.org/10.1039/d4bm00584h.
The mycobacterium lipid transporter MmpL3 is dimeric in detergent solution, SMALPs and reconstituted nanodiscs
Authors: Cioccolo Sara , Barritt Joseph D. , Pollock Naomi , Hall Zoe , Babuta Julia , Sridhar Pooja , Just Alicia , Morgner Nina , Dafforn Tim , Gould Ian , Byrne Bernadette
Published: July 2024

MmpL3 is an essential mycobacterial transporter. Extensive biophysical analysis reveals for the first time that MmpL3 exists as a dimer in different membrane mimetics.
Chemical synthesis of natural and azido-modified UDP-rhamnose and -arabinofuranose for glycan array-based characterization of plant glycosyltransferases
Authors: Pasini Irene , Ruprecht Colin , Osswald Uwe , Bittmann Andreas , Maltrovsky Lina , Romanò Cecilia , Clausen Mads H. , Pfrengle Fabian
Published: July 2024

Chemical syntheses of UDP-rhamnose and UDP-arabinofuranose and respective azido-modified analogues are reported. These UDP sugars were used on glycan microarrays for on-chip substrate specificity analyses of plant glycosyltransferases.
Solvent-induced structural regulation and luminescence switching of hybrid copper(i) halides for encryption and anti-counterfeiting applications
Authors: Liu Xia , Li Bohan , Jin Jiance , Yang Lin , Xia Zhiguo , Xu Yan
Published: July 2024

Copper(i) halides with different polyhedron units were obtained via solvent volatilization, showing consecutive structural evolution and photoluminescence tuning.
Integration of a model-driven workflow into an industrial pharmaceutical facility: supporting process development of API crystallisation
Authors: Pickles Thomas , Svoboda Vaclav , Marziano Ivan , Brown Cameron J. , Florence Alastair J.
Published: July 2024

Resource efficient yet scalable pharmaceutical crystallisation process development using a model-driven workflow.
Inclusion of halobenzene in water-mediated hydrogen-bonded architectures built from a V-shaped host molecule
Authors: Kawahata Masatoshi , Hyodo Tadashi , Kondo Rina , Tominaga Masahide , Yamaguchi Kentaro
Published: July 2024

Water-mediated hydrogen-bonded structures were built from a disubstituted adamantane with dimethoxyphenol moieties, where halobenzenes were accommodated within the cavity of cyclic dimers composed of host compounds and waters.
Effect of metal–ligand interactions on magnetic characteristics of two-dimensional Kagome structured perthiolated coronene (PTC) metal–organic frameworks (MOFs)
Authors: Fu Zijie , Zhang Yunfei , Jia Minghao , Zhang Shuo , Guan Lixiu , Xing Dan , Tao Junguang
Published: July 2024

Magnetic characteristics engineering of two-dimensional Kagome structured perthiolated coronene metal–organic frameworks.
Synergistic effects of rare-earth and lanthanoid elements on P123-modified Ni-HiMO catalysts for enhanced CO2 methanation under thermal and DBD-assisted conditions
Authors: Nguyen-Quang Minh , Azzolina-Jury Federico , Samojeden Bogdan , Motak Monika , Da Costa Patrick
Published: July 2024

For the first time, Ni(Mg,Al)Ox catalysts were optimized by Pluronic P123 and Sc, Y, La, and Gd for enhanced thermal and DBD-assisted CO2 methanation.
Retraction: Multifunctional luminescence sensing and white light adjustment of lanthanide metal–organic frameworks constructed from the flexible cyclotriphosphazene-derived hexacarboxylic acid ligand
Authors: Wang Meng , Gao Hong Wei , Li Jin Xiao , Bai Feng Ying , Xing Yong Heng , Shi Zhan
Published: July 2024

Retraction of ‘Multifunctional luminescence sensing and white light adjustment of lanthanide metal–organic frameworks constructed from the flexible cyclotriphosphazene-derived hexacarboxylic acid ligand’ by Meng Wang et al., Dalton Trans., 2021, 50, 14618–14628, https://doi.org/10.1039/D1DT02560K.
Comprehensive assessment of per and polyfluoroalkyl substances (PFAS) contamination in groundwater of Kamrup, Assam, India: occurrence, health risks, and metabolomic insights
Authors: Sharma Aditya , Jorvekar Sachin B. , Bhowmik Sujoy , Mohapatra Purusottam , Borkar Roshan M.
Published: July 2024

Per-and polyfluoroalkyl substances (PFAS) are synthetic chemicals that are known for their environmental persistence and adverse health effects.
Phytic acid derivatized lignin as a thermally stable and flame retardant material
Authors: Khodavandegar Saba , Fatehi Pedram
Published: July 2024

A phosphorus-containing flame retardant was produced via reacting phytic acid and kraft lignin in water.
Label-free optical detection of calcium ion influx in cell-derived nanovesicles using a conical Au/PDMS biosensor
Authors: Kwak Jisung , Kim Woochul , Cho Hyerim , Han Jiyun , Sim Sang Jun , Song Hyun Gyu , Pak Yusin , Song Hyun Seok
Published: July 2024

Label-free optical detection of calcium ion influx using nanovesicles: this study presents a conical Au/PDMS biosensor for detecting Ca2+ influx in A549-derived nanovesicles, providing a method for monitoring ion channel activity.
Colloidal synthesis of emission-tunable Cu-doped Zn–In–Se/ZnSe core/shell nanocrystals for lighting and bioimaging applications
Authors: Selvaraj Joicy , Mahesh Arun , Dhayalan Arunkumar , Baskaralingam Vaseeharan , Rajendran Saravanan , Pinilla Miguel Ángel Gracia , Paramasivam Thangadurai
Published: July 2024

Herein, environmentally benign CuI:Zn–In–Se/ZnSe core/shell luminescent inorganic nanocrystals (NCs) were synthesized via a phosphine-free one-pot, two-step organometallic approach with good colloidal quality.
Electronic structure of thin MoS2 films
Authors: Chambers Benjamin A. , Gibson Christopher T. , Andersson Gunther G.
Published: July 2024

The valence electron structure of exfoliated monolayer MoS2 deposited onto SiO2 was determined by UV photoelectron spectroscopy through component analysis in combination with Auger electron microscopy.
Modified Pd–HPMo@GNP as a highly effective electro-/nanocatalyst for the hydrogen evolution reaction and 4-nitrophenol reduction
Authors: Iniyan Selvaraj , Vijayaprabhakaran Aathilingam , Sebastian Christy , Kathiresan Murugavel
Published: July 2024

In light of current energy conversion paradigms, this study discusses the urgent need for the effective organic pollutant reduction and sustainable hydrogen production.
Horizons Community Board collection: setting new trends in energy storage and harvesting through innovative approaches
Authors: Ratha Satyajit , Ang Edison Huixiang
Published: July 2024

Materials Horizons and Nanoscale Horizons Community Board members Edison Huixiang Ang and Satyajit Ratha introduce their Community Board collection, highlighting some of the exceptional and timely research in the fields of energy storage and energy harvesting published in the journals.
A Br-triggered BiVO4 photoanode surface for efficient solar water splitting
Authors: Wang Yuhong , Cheng Qingqing , Cheng Weijie , Guo Shaoqing , Zhao Honghong , Gao Lizhen
Published: July 2024

Adding dopants to the structure and coupling cocatalysts on the surface are traditional strategies to inhibit carrier recombination and high catalytic barriers for enhancing the performance of water splitting of the BiVO4 photoanode.
Nanoporous air filtering systems made from renewable sources: benefits and challenges
Authors: Dutta Arnab , Karamikamkar Solmaz , Nofar Mohammadreza , Behzadfar Ehsan
Published: July 2024

Nanoporous air filtering systems made from renewable sources offer more sustainable alternatives for filter structures from conventional polymers.
Exploring structural and optical properties of CLSO:Dy for ultra-sensitive luminescent thermometers and high-bright screen printing
Authors: Zhang Xinyao , Sun Zhen , Lu Ruiying , Xu Jiarui , Xu Hongyu , Xu Wei
Published: July 2024

Ultra-sensitive thermometers and high-bright luminescent inks are successfully designed for accurate temperature detection and screen printing based on CaLa4Si3O13.
Responsive structural adaptability in ultra-microporous frameworks: guest recognition and macroscopic shape transformations induced by spin transitions within single crystals
Authors: Yang Yu-Ting , Guo Wei , Li Yu-Xia , Liu Zhi-Kun , Chai Yuqiao , Li Xing , Li Bao , Xue Jin-Peng
Published: July 2024

A coordination framework undergoes responsive structural adaptability, associated with spin-crossover activation and CO2/C2H2 separation. Dihydrogen bonds ensure efficient unit functions, enabling a macroscopic shape change in the single crystal.
From BaAlBO3F2 to BaAlB3O6F2 and BaAl2(B3O6)2F2: the enhancement of birefringence and band gap by extending the π-conjugated system combined with [Al–O/F] functional groups
Authors: Chen Cheng , Dou Danyang , Bai Yunjie , Zhang Bingbing , Wang Ying
Published: July 2024

Two new fluoroaluminoborates, BaAlB3O6F2 and BaAl2(B3O6)2F2, were designed and synthesized, exhibiting a markedly elevated birefringence in comparison with BaAlBO3F2.
One-pot photoenzymatic synthesis of β-chiral malononitrile derivatives
Authors: Fan Xin-Yue , Yu Yuan , Lin Ru-De , Yao Yao , Shi Ming-Liang , Li Kun , Yu Xiao-Qi , Liu Yan-Hong , Wang Na
Published: July 2024

Here, we reported a one-pot two-stage photoenzymatic synthesis route to prepare β-chiral malononitrile derivatives with mild reaction conditions and excellent enantioselectivity.
Biomimetic total synthesis of Horsfiequinone B enabled by a Friedel–Crafts alkylation (FCA)-type non-homodimerization
Authors: Li Lumin , Liu Ruiling , Yang Rui , Li Hanwei , Liu Ya , Zhan Rui , Wang Wen-Jing , Shao Li-Dong , Li Dashan
Published: July 2024

The first and biomimetic total synthesis of horsfiequinone B was achieved in 13 steps.
Design, synthesis, molecular docking and in vitro anticancer activities of 1-(4-(benzamido)phenyl)-3-arylurea derivatives
Authors: Sabale Prafulla , Sayyad Nusrat , Ali Abuzer , Sabale Vidya , Kaleem Mohammed , Asar Turky Omar , Ali Amena , Mujtaba Md. Ali , Anwer Md. Khalid
Published: July 2024

In both premenopausal and postmenopausal women, oestrogens play a critical role in the development of breast cancer.
Synthesis of azelaic acid copolyester plasticizers and their application in PVC
Authors: Zhang Wanjing , Wang Liyan , Chen Hong , Guo Liying , Bai Yaoyao , Qian Xin
Published: July 2024

PHMAZ copolyester plasticizers with different contents of 2-methyl-1,3-propanediol were synthesized. PHMAZ-45 showed the most favorable plasticizing effect on PVC.
High precision deep-learning model combined with high-throughput screening to discover fused [5,5] biheterocyclic energetic materials with excellent comprehensive properties
Authors: Liu Youhai , Yang Fusheng , Zhang Wenquan , Xia Honglei , Wu Zhen , Zhang Zaoxiao
Published: July 2024

In this study, we used D-MPNN embedded with features to rapid discovery of 6,7-trinitro-3H-pyrrolo[1,2-b][1,2,4]triazo-5-amine with high energy and excellent thermal stability. DFT calculations prove the performances of the targeting molecule.
Towards a ‘clicked’ PSMA targeting gene delivery bioconjugate-polyplex for prostate cancer
Authors: Noble Amanda R. , Akkad Saeed , Yates Nicholas D. J. , Jeffries James M. , Signoret Nathalie , Fascione Martin A.
Published: July 2024

We describe the construction of a prostate specific membrane antigen (PSMA) binding bioconjugate-polyplex, using ‘click’ chemistry, which we demonstrate is capable of targeted delivery of a GFP gene to PSMA overexpressing prostate cancer cells.
Innovative synthesis, structural characteristics, linear and nonlinear optical properties, and optoelectric parameters of newly developed A2ZnGeO4 (A = K, Li) thin films
Authors: Ben Yahya Sourour , El Karout Houda , Sahraoui Bouchta , Barillé Regis , Louati Bassem
Published: July 2024

The synthesis of high-quality thin films through spin coating deposition on meticulously cleaned glass substrates is presented.
Design, synthesis, and exploration of antibacterial activity of 6H-1,2-oxazin-6-ones
Authors: Alcántar-Zavala Eleazar , Delgado-Vargas Francisco , Marín-González Fabricio , Angulo Gabriela López , Aguirre-Madrigal Hugo Enrique , Ochoa-Terán Adrián , Rodríguez-Vega Gibrán , Aguirre-Hernández Gerardo , Montes-Avila Julio
Published: July 2024

This study reports the in silico design of 30 6H-1,2-oxazin-6-ones against DHFR and PTC antimicrobial targets.
Green and efficient synthesis of dibenzyl cyanamides and ureas with cyanamide as a block
Authors: Wang Zhongjie , He Yu , Wang Fang , Wang Yan , Luo Hui , Wu Jianglong , Yang Jinhui
Published: July 2024

A method for the two-step synthesis of dibenzyl cyanamide and dibenzyl urea via cyanamide is presented.
Thermo-rheological and kinetic characterization and modeling of an epoxy vitrimer based on polyimine exchange
Authors: Lorenz Niklas , Dyer William E. , Kumru Baris
Published: July 2024

Accurate modelling of epoxy-imine-based vitrimer for composite applications: Cure kinetics, thermo-rheological behaviour, glass transition temperature development.
Quantification probing of available extra capacity: interfacial space-charge storage in FeOOH lithium-ion batteries
Authors: Zhang Leqing , Bu Zeyuan , Fu Haoyu , Wang Xiaoshan , Meng Xianyi , Liu Meishuo , Zhou Yakun , Sui Xiang , Chen Guihuan , Li Qinghao , Li Qiang
Published: July 2024

Operando magnetometry shows evolution of paramagnetism FeOOH in LIBs: rising/falling magnetism from superparamagnetism Fe reduction/interfacial space-charge storage (reversible extra capacity) during discharge, which is reversed during charge.
Multifunctional wrinkled nacreous all-carbon films for high-performance stretchable strain sensors and supercapacitors
Authors: Cho Soo-Hyeon , Lim TaeGyeong , Lee Hyeon-Jong , Kim Sang-Yun , Suk Ji Won
Published: July 2024

The “brick-and-mortar” carbon composite film on stretchable adhesive, utilizing rGO as bricks and CNT as mortar enabled the development of high-performance stretchable strain sensors and supercapacitors.
Machine learning interatomic potentials in engineering perspective for developing cathode materials
Authors: Kwon Dohyeong , Kim Duho
Published: July 2024

Machine learning interatomic potentials (MLIPs) predict thermodynamic phase stability and structural parameters like density functional theory (DFT) but are much faster, making them valuable for engineering applications.
A polystyrene resin in situ supported PANI/Fe3O4 composite as a heterogeneous Fenton catalyst for the efficient degradation of tetracycline in water
Authors: Xu Jiaming , Zhang Heng , Ma Jinmao , Zhou Lincheng , Zhao Quanlin , Ye Zhengfang
Published: July 2024

A ternary composite heterogeneous Fenton catalyst, PANI/Fe3O4/APS, is developed for efficient catalytic degradation of TC, encompassing material preparation, reaction mechanism research and practical application.
Assessing the impact of an antisolvent-regulated ZnCl2 water-in-salt electrolyte on solvation structure: a multiscale computational validation for aqueous Zn-ion battery application
Authors: Sethi Asis , Rajeev Chaithra , Kumar U. Anil , Sharma Parul , Sunda Anurag Prakash , Dhavale Vishal M.
Published: July 2024

Molecular insights into methanol as an antisolvent in ZnCl2 water-in-salt electrolyte (WiSE) and experimental evaluation of their performance-cum-efficiency for an aqueous zinc-based battery are presented.
Mussel-inspired sticky self-healing conductive hydrogels composites for physiological electrical sensing
Authors: He Ming-Lin , Chen Nai-Feng , Wang Pei Xiang , Chen Hsin-Ya , Lai Wan-Yi , Liao Pei-Tun , Yu Jiashing , Wei Yang , Chung Ren-Jei , Hsu Chun-Hsien , Chen Shiu-Jau , Chang Ting-Ting , Lee Wen-Ya
Published: July 2024

Inspired by mussels, this work introduces a self-healing conductive adhesive that not only adheres tenaciously to various surfaces in wet conditions but also demonstrates exceptional conductivity for the detection of electrophysiological signals.
Integrating NiFe bimetal sites into a conjugated microporous polymer for boosting photocatalytic selective aromatic alcohol oxidation
Authors: Guo Shien , Yu Zhen , Xu Chao , Wang Zhipeng , Tao Wei , Tang Qiaoya , Liu Zhenghui , Xiao Yuting
Published: July 2024

A conjugated porous polymer metalated with Ni and Fe sites (NiFe-CMP) has been rationally designed and synthesized, exhibiting excellent photocatalytic activity and selectivity in the oxidation of aromatic alcohols under visible light irradiation.
A comprehensive review on the role of strontium in biodegradable metals
Authors: Li Huafang , Ma Luqing
Published: July 2024

The role of strontium in biodegradable metals.
Maneuvering the mineralization of self-assembled peptide nanofibers for designing mechanically-stiffened self-healable composites toward bone-mimetic ECM
Authors: Mavlankar Nimisha A. , Nath Debasish , Chandran Yadu , Gupta Nidhi , Singh Ashmeet , Balakrishnan Viswanath , Pal Asish
Published: July 2024

A bioinspired approach develops bone-ECM mimetic hybrids with nonlinear mechanical properties by templating bioactive glass on nanofibers derived from amyloid-inspired peptide amphiphiles, resembling collagen-bridged hydroxyapatite.
Fabrication of conjugated polymers with aggregation-induced near-infrared-II emission for efficient phototheranostics
Authors: Han Hui , Xue Yuwen , Yang Yafeng , Chen Kai , Sun Pengfei , Shen Qingming , Fan Quli
Published: July 2024

NIR-II conjugated polymers with typical AIE characteristics have been fabricated for bight NIR-II fluorescence imaging guided photothermal therapy of cancer.
Tuning the fluorescence emission of DADQ based molecular solids by dielectric environment variation
Authors: Mahajan Nikita , Radhakrishnan T. P.
Published: July 2024

Fluorescence emission of DADQ based molecules is shown to be easily tuned by exposure to mild acids and the mechanistic basis for this involving the dielectric environment variation is explored.
Achieving 18.92% efficiency of non-fullerene organic solar cells with active layer morphology optimization by regulating solvent evaporation dynamics
Authors: Li Mandi , Zhang Fenghua , Li Xiong , Wang Dan , Liu Yang , Xu Denghui , Zhao Jia , Zhu Yaohui , Zhou Jun
Published: July 2024

18.92% efficiency of D18:L8-BO organic solar cells achieved by regulating the solvent evaporation process using CF : Tol mixed solvent.
Self-Report of Changes in Cognitive-Communication Function and Social Engagement Among Adults With Cancer-Related Cognitive Impairment
Authors: Geels Patricia L. , Flynn Karen , Fogarty Kieran J. , Lyerla Rob
Published: July 2024

Purpose:

This study aimed to examine the prevalence of cognitive-communication deficits in adult cancer survivors who reported experiencing cancer-related cognitive impairment (CRCI). The study also aimed to determine how these problems impact their ability to engage socially and find satisfaction in their social roles.

Method:

This study employed a cross-sectional survey to collect data from adult cancer survivors. The survey included questions on demographic characteristics, self-perceived cognitive-communication abilities, social engagement, and satisfaction with social participation. Data analysis included descriptive statistics, Spearman rank-order correlation, Mann–Whitney
U
tests, and Kruskal–Wallis
H
tests.

Results:

Of 172 participants, 78% completed the survey, with 109 self-reporting CRCI. The participants predominantly had breast cancer, and most were diagnosed with Stage II cancers. The results indicated self-perceived impairment in various cognitive-communication domains, with functional daily communication being the most affected. Participants reported more difficulty participating in social roles and activities than their overall satisfaction with social participation. This study explored the relationships between cognitive-communication scores and social engagement, considering variables such as education, cancer type, stage, age, and treatment.

Conclusions:

This study underscores the multidimensional nature of CRCI, emphasizing the importance of addressing both cognitive-communication and social aspects in interventions and support services. It highlights the clinical implications for speech-language pathology, suggesting a potential role in identifying and addressing cognitive-communication deficits. Future research needs are discussed.
Recent developments in carbon‐based electrodes surface modification for zinc bromine flow battery
Authors: Li Yanhong , Sun Xiaoyun , Meng Lin , Wang Xingxing , Ouyang Boxue , Wang Deren , Zhao Chenyu , Hu Haochen
Published: July 2024

Zinc‐bromine flow batteries (ZBFBs) hold promise as energy storage systems for facilitating the efficient utilisation of renewable energy due to their low cost, high energy density, safety features, and long cycle life. However, challenges such as uneven zinc deposition leading to zinc dendrite formation on the negative electrode and parasitic hydrogen evolution reaction during charging pose risks of membrane puncturing and short circuits, thereby limiting energy density improvements. Additionally, the sluggish and non‐reversible Br2/Br− redox reaction hampers battery power density enhancements. Given that electrode properties significantly influence the rate and reversibility of these redox reactions, modifications to the negative and positive electrodes are crucial. While inert carbon‐based electrodes are favoured for their corrosion resistance and conductivity, their hydrophobic nature and low electrochemical activity restrain the performance of ZBFBs. The authors present a comprehensive review of recent advancements in both negative and positive electrode modifications in ZBFBs. It also puts forward future research directions aimed at overcoming existing challenges, with the ultimate objective of promoting the efficient utilisation of ZBFBs.
Convergence analysis and mesh optimization of finite element analysis related to helical springs
Authors: Cadet Guillaume , Paredes Manuel
Published: July 2024

Helical springs are widely used in engineering applications. In order to reduce cost in “try and error” time consuming experimental campaigns, numerical simulations became an essential tool for engineers. Indeed, it saves considerable time in the ahead design phase of a project to ensure the feasibility of structures. However, these simulations run thanks to a lot of parameters, which all must be selected carefully to get access to reliable results. In this paper, ten main modeling parameters are presented. Thanks to a valuable literature statistical analysis, seven of them are settled. Three remain to be studied: the mesh density, the order of the elements and the integration method. Then, three convergence analyses are performed with ABAQUS about the circular geometry accuracy of the tessellated surface, the axial stiffness (and axial load) accuracy of the helical spring and the maximal Von Mises stress accuracy within the helical spring. The numerical campaign is led with 8 mesh densities along the circumference and 6 element types. After comparison, in order to get both fast and accurate results, a limited list of near-optimal combination of density and element type are proposed. The users are free to use any of the presented solutions in function of the desired admissible accuracy of their model.The proposed meshing technique can be exploited for any helical structure with circular cross section, mainly loaded in torsion and shear, such as extension and compression springs.
A comprehensive review on human–robot collaboration remanufacturing towards uncertain and dynamic disassembly
Authors: Xiao Jinhua , Huang Kaile
Published: July 2024

With the continuously increasing volumes of End-of-Life (EOL) products and the emergence of Industry 4.0-related technologies, the manual labor-intensive disassembly in remanufacturing process is gradually shifting towards human–robot collaboration (HRC) disassembly. However, it is necessary to consider the most commonly approach in current robot-involved automatic disassembly with the high efficiency and adaptability. The purpose of this paper is to summarize the existing human–robot collaboration disassembly technologies to further discuss the possible applications of various technologies in the disassembly process, thereby providing the comprehensive reviews of future research directions. The paper presents an analysis of the technical issues encountered in the HRC disassembly process, which provides a summary of the intelligent disassembly platform with robot agents as the core, focusing on the optimization of HRC disassembly. Furthermore, the relevant technologies are reviewed to discuss the intelligent disassembly systems, including Cyber-Physical systems (CPS), Internet of Things (IoT), Cloud Computing, Artificial Intelligence (AI), and Digital Twins (DT). The industrial applications of various optimization methods have discussed the potential research trends in the collaboration of multiple robots and humans in disassembly with the perspectives of task allocation, collaborative decision-making, and performance evaluation, focusing on the application trends of digital twin technology in industrial disassembly lines.
How do emotional tones, involvement in the situation, perception and technical adaptations interplay in elite athletes’ performance optimization? A case study in Formula Kite
Authors: Terrien Eric , Genevey Marie-Lou , Kermarrec Gilles , Saury Jacques
Published: July 2024

It is widely accepted in sports psychology that emotions and performance are interrelated. However, the interplay between athletes’ emotions and the associated involvements in the situation, perceptions and technical adaptations has remained largely unexplored in ecological sport settings. Therefore, the purpose of the present study is to use an activity-centered approach to apprehend these links in an ecological setting. We used the theoretical and methodological framework of the course of experience to analyze the activity of two elite Formula Kite riders during speed tests. Our results highlight that during the speed tests, the riders’ pleasant emotional tones were associated with technical adaptations mostly related to global involvements in the situation and global sources of perturbation, while unpleasant emotional tones were associated with more specific involvements in the situation and local sources of perturbation. Furthermore, pleasant and unpleasant emotional tones were associated with different technical adaptations. Altogether, the results of the study emphasize the interest of apprehending the athlete’s performance optimization through a holistic viewpoint taking into consideration both the athletes’ emotions and their modes of technical adaptation to dynamic sport situations “in the doing”.
INTEGRATE-ADHD: Vergleich und Integration administrativer und
epidemiologischer ADHS-Diagnosedaten durch klinisches Assessment – Vorstellung
des Projekts
Authors: Schlack Robert , Beyer Ann-Kristin , Beck Lilian , Hölling Heike , Pfeifer Stefan , Romanos Marcel , Jans Thomas , Hetzke Leila , Berner Annalena , Weyrich Sophia , Scholz Vanessa , Ravens-Sieberer Ulrike , Kaman Anne , Gilbert Martha , Reiß Franziska , Greiner Wolfgang , Witte Julian , Hasemann Lena , Heuschmann Peter , Fiessler Cornelia , Widmann Jonas , Riederer Cordula
Published: July 2024

Als eine der am häufigsten diagnostizierten psychischen Störungen im Kindes- und
Jugendalter mit zum Teil schwerwiegenden individuellen, familiären und sozialen
Konsequenzen hat die Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) eine
hohe gesellschaftliche und gesundheitspolitische Relevanz. Für Deutschland
wurden aus den Daten gesetzlicher Krankenkassen über Jahre steigende
ADHS-Diagnoseprävalenzen gemeldet, während epidemiologische Daten konstante,
zuletzt sogar sinkende Prävalenzraten auswiesen. Die klinische Validität von
Diagnosen aus beiden Datenquellen ist unbekannt. Im Konsortialprojekt
INTEGRATE-ADHD wurden 5461 Eltern von bei der drittgrößten bundesweiten
gesetzlichen Krankenkasse (DAK-Gesundheit) versicherten Kindern im Alter von 0
bis 17 Jahren mit einer gesicherten administrativen ADHS-Diagnose in mindestens
einem Quartal des Jahres 2020 mit den Fragebögen der epidemiologischen KiGGS-
und BELLA-Studie zur ADHS-Diagnose und -Symptomatik ihres Kindes und zu weiteren
Themenbereichen, darunter Komorbidität, Inanspruchnahme von Leistungen des
Gesundheitssystems, Versorgungsqualität und -zufriedenheit, psychosoziale
Risiko- und Schutzfaktoren sowie gesundheitsbezogene Lebensqualität online
befragt. Darüber hinaus wurde eine Substichprobe von 202 Kindern und
Jugendlichen mit einer an der AMWF-S3-Leitlinie ADHS orientierten klinischen
Diagnostik untersucht. Ein wichtiges Ziel des Projekts ist es, mittels
Data-Linkage mögliche Ursachen für die oftmals divergierenden
Prävalenzschätzungen aus epidemiologischen und administrativen Daten zu
identifizieren sowie die Datenquellen mittels einer leitlinienbasierten
klinischen Diagnostik zu integrieren und zu validieren, auf diese Weise zu einer
genaueren bevölkerungsbezogenen Prävalenzschätzung der ADHS bei Kindern und
Jugendlichen beizutragen sowie tatsächliche oder vermeintliche Widersprüche
zwischen den Datenquellen aufzuklären. Das Data-Linkage-Projekt INTEGRATE-ADHD
verbindet administrative, epidemiologische und klinische ADHS-Diagnosedaten zu
einem „dreidimensionalen Blick“ auf die ADHS-Diagnose. Die Ergebnisse dienen der
Identifikation von Handlungsfeldern für die Gesundheitspolitik und die
Selbstverwaltung im deutschen Gesundheitssystem sowie der Ableitung von
Empfehlungen für die Akteure und Stakeholder im Bereich ADHS. Erste Ergebnisse
werden 2024 veröffentlicht.
CT in pediatric trauma patients
Authors: Appelhaus Stefan , Schönberg Stefan O , Weis Meike
Published: July 2024

The decision as to whether to perform a computed tomography (CT) examination in severe pediatric trauma poses a challenge. The therapeutic benefit of computed tomography in injured children is lower compared to adults, while the potential negative effects of ionizing radiation may be higher. Thus, the threshold for CT should be higher. Centers that less frequently treat pediatric cases tend to conduct more whole-body CT examinations than dedicated pediatric trauma centers, indicating a clinical overestimation of injury severity with subsequently unnecessary imaging due to inexperience. On the other hand, a CT scan that is not performed but is actually necessary can also have negative consequences if an injury is detected with a delay. An injured child presents a challenging situation for all involved healthcare providers, and thus requires a structured approach to decision-making.

Selective literature review of the benefits and risks of CT in injured children, as well as indications for whole-body and region-specific CT imaging.

This article provides an overview of current guidelines, recent insight into radiation protection and the benefits of CT in injured children, and evidence-based decision criteria for choosing the appropriate modality based on the mechanism of injury and the affected body region.
Computed tomography-based radiomics machine learning models for differentiating enchondroma and atypical cartilaginous tumor in long bones
Authors: Hong Rui , Li Qian , Ma Jielin , Lu Chunmiao , Zhong Zhiwei
Published: July 2024

To explore the value of CT-based radiomics machine learning models for differentiating enchondroma from atypical cartilaginous tumor (ACT) in long bones and methods to improve model performance.

59 enchondromas and 53 ACTs in long bones confirmed by pathology were collected retrospectively. The features were extracted from preoperative CT images of these patients, and least absolute shrinkage and selection operator (LASSO) regression was used for feature selection and dimensionality reduction. The selected features were used to construct classification models by thirteen machine learning algorithms. The data set was randomly divided into a training set and a test set at a proportion of 7:3 by ten-fold cross-validation to evaluate the performance of these models.

A total of 1199 features were extracted, 9 features were selected, and 13 radiomics machine learning models were constructed. The area under the curve (AUC) of 11 models was more than 0.8, and that of 3 models was more than 0.9. The Extremely Randomized Trees model achieved the best performance (AUC = 0.9375 ± 0.0884), followed by the Adaptive Boosting model (AUC = 0.9188 ± 0.1010) and the Linear Discriminant Analysis model (AUC = 0.9062 ± 0.1459).

CT-based radiomics machine learning models had great ability to distinguish enchondroma and ACT in long bones. By using filters to deeply mine high-order features in the original image and selecting appropriate machine learning algorithms, the performance of the model can be improved.
Transparenz geht anders
Authors: Lukuc Sarah
Published: July 2024

Seit Mai ist der Klinik-Atlas des Bundesgesundheitsministeriums online. Leider mit erheblichen Mängeln.
Und auch nach einem Update sind die Klinikdaten oft veraltet und weisen massive Fehler auf. Worauf die
Krankenhäuser nun achten sollten, lesen Sie hier.
Olfactory Groove Meningiomas and the Association with Postoperative Weight Loss
Authors: Armstrong Stephanie A. , Boerger Timothy F. , Laing Brandon , Tavakoli Samon , Goetschel Kaitlin , Cheok Stephanie , Zwagerman Nathan
Published: July 2024

Objective Olfactory groove meningiomas (OGM) commonly present with olfactory deficits and compression of the frontal lobes. Given the relationship to dietary behaviors, our objective was to evaluate the relationship between OGMs and postoperative weight loss.

Methods Retrospective review of primary resection of meningiomas between 2017 and 2023 at a single institution was conducted. Neurofibromatosis type 2, pregnancy, weight loss medications, or surgeries were excluded. Data collection included preoperative body mass index (preBMI) and postoperative BMI (poBMI) at 3 to 6 and 12 months. Percent BMI change (pcBMI) was calculated by (poBMI − preBMI/preBMI × 100%). IBM SPSS Statistics (Version 27) was used for descriptive statistics and stepwise multiple linear regression.

Results Ninety-eight patients met inclusion with a mean age of 57.58 years. Three groups were stratified by location: OGM (n = 15), anterior cranial fossa excluding OGM (ACF; n = 24), and other (OTH; n = 59). Olfactory dysfunction was present in 53.8% of the OGMs. OGM presented with significantly larger lesions (57.25 ± 55.98 mm3) and a higher preBMI (34.58 ± 7.41 kg/m2) than ACF and OTH. A greater pcBMI was seen in OGM at both timepoints (−7.74%, −8.73%). OGM location, tumor volume, and preBMI were found significant on univariate analysis (p < 0.05) and included in multiple linear regression. All regression models were significant (p = 0.001). Location significantly added to the prediction at 3 to 6 and 12 months as well as preBMI at 12 months. In a subanalysis of ACF and OGM, OGM location was significantly associated with negative pcBMI at 3 to 6 and 12 months.

Conclusion OGMs are associated with higher preoperative weight and greater weight loss postoperatively compared with other locations.
Effectiveness of 0.2% Hyaluronic Acid on Clinical, Biomolecular and Microbiological Parameters in Type 2 Diabetes Mellitus Patients with Periodontitis
Authors: Devina Anggun Alfreda , Halim Felita Clarissa , Meivi Meivi , Masulili Sri Lelyati C. , Tadjoedin Ette Soraya Shahnaz , Lessang Robert , Widaryono Adityo , Bachtiar Boy M. , Sulijaya Benso , Tadjoedin Fatimah Maria , Haerani Natalina , Harsas Nadhia Anindhita , Bakker Astrid Diana
Published: July 2024

Objective This double-blind randomized clinical trial assessed the effectiveness of 0.2% hyaluronic acid (HA) gel as an adjunct to scaling and root planning (SRP) in patients with periodontitis and type 2 diabetes mellitus (DM), focusing on changes in clinical periodontal parameters, the expression of inflammatory mediators, and oral pathogens.

Materials and Methods The randomized clinical trial involved 36 participants, 18 DM patients, and 18 healthy patients. The participants in each group were randomly assigned to receive placebo or HA gel after SRP. Gingival crevicular fluid and subgingival plaque samples were taken before treatment and at 4-week follow-up. Clinical parameters, interleukin-1β (IL-1β) and IL-10 levels, and proportions of Porphyromonas gingivalis (Pg) and Fusobacterium nucleatum (Fn) were evaluated at baseline and follow-up.

Statistical Analysis Paired t-test (parametric data) or Wilcoxon signed-rank test (nonparametric data) was used for intragroup comparison between baseline and follow-up, and comparisons between groups one-way analysis of variance test (parametric data) or Kruskal–Wallis test (nonparametric data).

Results At 4 weeks, most of the groups showed statistically significant decreases (p ≤ 0.05) in various clinical and biomolecular parameters. However, there were exceptions: the pocket probing depth (PPD) and clinical attachment loss (CAL) parameter did not significantly decrease for the placebo (p > 0.05) non-DM group, and the IL-10 parameter in the DM HA gel group (p = 0.108). Regarding bacterial proportions, the non-DM and DM placebo group exhibited significant test results for Pg after 4 weeks (p ≤ 0.05). In the case of Fn bacteria proportions, they decreased in all groups, but these results were not statistically significant (p ≥ 0.05). An intergroup analysis revealed no significant differences (p ≤ 0.05) for bleeding on probing (BOP), PPD, and both proinflammatory and anti-inflammatory cytokines. Only clinical attachment loss (CAL) exhibited a statistically significant intergroup difference 0.042.

Conclusion The use of 0.2% HA gel into periodontal pockets alongside SRP, for both diabetic and healthy individuals, showed no statistically significant variances in clinical, biomolecular, and microbiological measures.
Skeletal Manifestations of Gaucher's Disease: A Case Report and Literature Review
Authors: Mohamed Rahma Nour Eldin Saad , Elnahal Walid A. , Furtado Cleofina , Zeitoun Rania , Abdel-Wahab Nagui
Published: July 2024

Gaucher's disease (GD) is a lysosomal storage disorder characterized by the storage of glucosylceramide in macrophages (“Gaucher cells”), mainly in the reticuloendothelial system. GD type 1 (GD1) is the most common phenotype that usually manifests with hepatosplenomegaly, cytopenias, and bone involvement. Skeletal manifestations are the most debilitating characteristic and result in significant morbidities. We describe a case of GD1, first presented by a nontraumatic bone fracture. The case presentation highlights the importance of considering GD among the differential diagnosis of nontraumatic fractures, avascular necrosis, and infarcts of the bones. Early diagnosis and treatment improve the course of disease and avoid irreversible sequelae.
Imaging of Disease and Normal Variant Patterns in Pediatric Hips
Authors: Anderson Jade A. , Laucis Nicholas , Symanski John , Blankenbaker Donna
Published: July 2024

The pediatric hip undergoes significant changes from infancy through adolescence. Proper maturation is crucial for the development of a stable and functional hip joint. Imaging interpretation of the pediatric hip requires distinguishing normal variants and maturation patterns from pathology. We review femoral ossification centers, variants, and conditions that affect the proximal femur, such as Legg-Calvé-Perthes disease; the acetabulum, such as developmental hip dysplasia; the acetabular labrum, such as femoroacetabular impingement; and synovial pathology in children through adolescence. Understanding the spectrum of hip conditions and using advanced imaging techniques are essential for the accurate diagnosis and effective management of pediatric hip disorders.
Clinical Outcome Success of Silver-Modified Atraumatic Restorative Treatment (SMART) in Treating Children with Dental Caries in Primary Teeth: A Systematic Review
Authors: Mohapatra Subhashree , Mohandas Rahul
Published: July 2024

Objective: A novel approach called silver-modified atraumatic restorative therapy (SMART) integrates glass ionomer cement (GIC) restorations with silver diamine fluoride (SDF). This new method combines the ability of GIC to seal the tooth and sever the nutrition that bacteria require to proliferate, with the bactericidal power of SDF. The purpose of this review is to evaluate and compare the available data regarding the efficacy of the SMART approach in treating children's carious primary teeth.

Materials and Methods: The earliest date accessible up until February 15, 2024, was thoroughly searched in databases including Scopus, PubMed, Cochrane, Science Direct, Lilacs, Science Direct, Web of Science, and Google Scholar. The review only comprised randomized controlled trials. The PICO strategy (P: Children with dental caries in primary teeth; I: SMART; C: Conventional drill and fill method or atraumatic restorative treatment [ART] therapy; O: Clinical success) was adopted. Risk of bias assessment and quality of evidence were assessed using the RoB-2 tool and GRADE tool, respectively.

Results: Four full-text publications that met the eligibility criteria underwent additional processing for data extraction and qualitative analysis. In three studies, no difference was found in the clinical performance of SMART and conventional drill and fill/ART therapy, whereas in one study, the clinical performance of SMART was found to be better than the conventional ART therapy.

Conclusion: SMART and conventional drill and fill/ART techniques have comparable clinical performance for carious primary teeth of children. SMART can be used to treat asymptomatic deep carious lesions as well as apprehensive children. However, the cost-effectiveness of SMART restorations needs to be investigated in a variety of demographics.
Comparative Analysis of Supratentorial Intraventricular Tumors in Adults and Pediatrics in a Developing Country: Clinicopathological Features, Surgical Management, and Outcomes
Authors: Mishra Sandeep , Mishra Saurav , Regmi Sabina , Katiyar Varidh , Verma Satish , Satyarthee Guru Dutt , Garg Kanwaljeet , Mishra Shashwat , Sharma M.C. , Singh ManMohan , Kale Shashank Sharad
Published: July 2024

Background Supratentorial intraventricular tumors, encompassing lateral and third ventricular tumors, are uncommon intracranial neoplasms, typically slow-growing and benign, manifesting symptoms only upon reaching a substantial size. This study aims to identify optimal surgical approaches, assess the prevalence and characteristics of these tumors, and evaluate postoperative outcomes among pediatric and adult age groups.

Methods A retrospective comparative study at a tertiary care hospital from January 2014 to June 2020 included 165 patients (68 pediatrics, 97 adults) meeting inclusion criteria for intraventricular tumor management. Data covered demographic factors, clinical history, neurological assessments, neuroimaging, surgical approaches, histopathological diagnoses, immunohistochemical features, adjuvant therapies, follow-up status, postoperative complications, and morbidity/mortality.

Results Ventricular tumor incidence showed male preponderance in both adults (M:F = 1.2:1) and pediatrics (M:F = 3:1). Lateral ventricles were the most common location. Pediatric cases exhibited more frequent calcifications on computed tomography scans (35.6% vs. 29.5%). Grade II and III tumors were more prevalent in adults within the lateral ventricle (27.1 and 1.9%) compared with pediatrics (6.5 and 8.4%). The third ventricle predominantly featured benign lesions, with pediatric patients experiencing significantly longer hospital stays (16.12 ± 21.94 days vs. 9.58 ± 6.21 days) (p = 0.006). Adults and pediatric patients showed a significant difference in high-grade lateral ventricle tumors (p-value = 0.002*).

Conclusions Supratentorial ventricular tumors are relatively more prevalent in children than adults, presenting challenges due to size and bleeding risks. Surgical resection is the primary treatment, with a focus on the optimal approach for gross total excision to reduce recurrence risk.
Why do states discriminate between refugee groups? Understanding how Syrian and Ukrainian refugees were framed in Germany and Poland
Authors: Drewski Daniel , Gerhards Jürgen
Published: July 2024

Previous studies hypothesize that countries discriminate between refugee groups of different backgrounds depending on cultural similarity to the host population and whether they flee from a rivaling regime. We argue that these explanations miss how political actors frame the collective identity of the host nation and the refugees in political discourse, and the nation state-specific cultural repertoires they draw on. The different responses of the German and Polish governments to Syrian and Ukrainian refugees are a case in point. While Poland welcomed Ukrainian and rejected Syrian refugees, Germany differentiated relatively little between Syrian and Ukrainian refugees in terms of its admission policy. Based on a qualitative analysis of parliamentary debates in Germany and Poland, we show that the German government employed mostly “cosmopolitan” frames by highlighting Germany’s humanitarian orientation, the commitment to international law, and the principles of liberal democracies. In contrast, the Polish government employed mostly “communitarian” frames by highlighting Poland’s national sovereignty and drawing strong cultural boundaries.
Socially-distanced science: how British publics were imagined, modelled and marginalised in political and expert responses to the COVID-19 pandemic
Authors: Ballo Rokia , Pearce Warren , Stilgoe Jack , Wilsdon James
Published: July 2024

In early 2021, the United Kingdom (UK) had the highest per capita death rate from Covid-19 of any large country. Yet it had previously been ranked as one of the best prepared countries for a future pandemic. This gap between preparedness and performance has been the subject of intense debate, including as part of the UK Covid-19 Inquiry. In this paper, we contribute to this ongoing process of reflection by identifying the imagined public(s) within the UK’s scientific advice system. Drawing on scholarship in Science and Technology Studies (STS) that critiques framings of a singular or homogeneous ‘public’, we review meeting minutes and media briefings to reveal two imagined publics, co-constructed by the UK’s science advisors and policymakers in early 2020: first, a ‘freedom-loving’ public resistant to stringent policy interventions; and second, a public that was—in an echo of wartime rhetoric— ‘all in it together’. These imagined publics reflect a series of framing assumptions that help to make sense of the UK’s pandemic response. We focus particularly on the tensions between the homogeneous and multi-faceted imagined public, and the compound health and social inequalities that predated the pandemic but became starker and more visible as it unfolded. Our paper charts these tensions and demonstrates how these imagined publics went through stages of cohesion and fracture in the fraught early months of the pandemic. We conclude by considering the implications of this analysis for understanding the UK’s response to Covid-19, and for the future of scientific advice and emergency preparedness. Why does this matter? Studies of scientific advice reveal that how scientists and decision makers imagine the public and their concerns affect the communication of scientific advice, and the construction and value placed on relevant knowledge. Advisory scientists frame their models and their advice in terms of what they regard as politically possible.