bluuebunny/crossref_metadata_2025 huggingface dataset:
Konsep Diri Korban Kekerasan Seksual dalam Perspektif Komunikasi Intrapersonal
Authors: Rumaisha Alwi Zulaikha , Fitriani Dinda Rakhma
Published: January 2024

Research on the phenomenon of sexual violence against women continues to persist to this day, both in urban and rural areas, with the number of violence cases steadily increasing each year. The repercussions of these sexual violence actions are immensely grave, causing victims to experience a range of traumas. Some victims may endure mild trauma, allowing them to maintain communication with others, while others suffer severe trauma, rendering them incapable of meeting or communicating with anyone else. Some victims even withdraw into their rooms, attempt self-harm, or contemplate ending their own lives. One crucial aspect in comprehending the impact of sexual violence against women is the victims' self-concept. The primary objective of this research is to analyze the self-concept of women who have fallen victim to sexual violence, with a focus on intrapersonal communication perspectives and the self-acceptance processes of these victims. The research employs a qualitative method with a phenomenological approach, which enables researchers to delve into an understanding of the victims' experiences. The research findings reveal that the intrapersonal communication process in the four informant victims of sexual violence occurs progressively. Each informant undergoes a complex and intricate self-acceptance process. However, the conclusion drawn from this research is that the informants ultimately succeed in developing a positive self-concept despite enduring a challenging journey. Therefore, this research offers valuable insights into how victims of sexual violence respond and cope with their traumatic effects through intrapersonal communication and self-acceptance.
Strukturasi Adaptif Penggunaan Teknologi Informasi pada Instansi Pemerintahan
Authors: Rosalia Fanny
Published: January 2024

The implementation of periodic monitoring and evaluation is one of the keys to the successful implementation of bureaucratic reform in an organization. Various ways are carried out so that the implementation of evaluation monitoring is carried out periodically by each organization. Various components become objects that must be monitored and evaluated continuously. This is not an easy thing to do with its various complexities. One of the government agencies has implemented Information Technology as one of the efforts to implement scheduled, up to date and optimally evaluated bureaucratic reforms. With an adaptive structuring theory approach, this study aims to see how the adaptive structuring process in the use of e-monitoring applications qualitatively by interviewing a number of respondents who are Civil Servants in each Working Group in eight areas of bureaucratic reform changes. The results showed that the use of e-monitoring application is the process of structuring information technology on rules and resources produced and reproduced by users in the organization. Then there is an interplay between the information technology structure ofe-monitoring with the structure of features, other structures, and internal organizational systems.  Adjustments made in interacting also give rise to a new structure that is continuously carried out by users so that it is legitimized in the use of e-monitoring as a process of monitoring and evaluating the implementation of bureaucratic reforms.
Implementasi Fungsi Kontrol dan Perekat Sosial RRI Pro 1 Bengkulu dalam Menjaga Eksistensi NKRI
Authors: Putri Elezka Duwi , Budiman Dwi Aji , Sari Eka Vuspa
Published: January 2024

This research aims to determine the implementation of the control and social glue functions of RRI Pro 1 Bengkulu in maintaining the existence of the Republic of Indonesia. RRI Bengkulu, as part of RRI as well as a broadcasting institution, also helps realize Indonesia's national ideals because its broadcasts must be educational, ensuring the diversity and plurality of Indonesian society so that its integrity and existence are maintained within the Republic of Indonesia. Due to the low number of audiences, it is necessary to maximize the function of control and social glue so that audiences remain popular and reconcile them so that the existence of the Republic of Indonesia can be maintained. The research method uses a qualitative-descriptive approach with data collection techniques through interviews, documentation and literature studies. Research data is divided into two sources, namely primary and secondary data. The primary data for this research was obtained from interviews with informants as well as indirect secondary data. It aims to complement and support the primary data so that it is relevant to the research focus. The research results show that RRI Pro 1 Bengkulu carries out and implements social control and glue functions optimally through news and broadcast programs, including dialogue programs using social media like Instagram and YouTube. RRI Pro 1 Bengkulu has succeeded in implementing its control function by presenting accurate, balanced and critical information on various issues relevant to the existence of the Republic of Indonesia. Apart from that, the social glue role of RRI Pro 1 Bengkulu is reflected in various programs that promote culture, diversity and national values. In this context, RRI Pro 1 Bengkulu not only functions as a transmitter of information but also as an agent of social change that contributes positively to the formation of national identity and maintains unity amidst the dynamics of society. The implications of these findings provide new insights for the mass media and related stakeholders to continue to optimize their role in supporting the existence of the Republic of Indonesia. People get information or insight, and then various perspectives emerge. This diversity is tolerated, therefore the situation in society is conducive; it can be interpreted that society as a unified whole is maintained, and the existence of the Republic of Indonesia remains. The right decision is that RRI Bengkulu and its programs and RRI in the Republic of Indonesia region continue to carry out their broadcast programs in a sustainable manner by paying attention to aspects of adaptation to current changes, such as digitalization.
Phubbing, Komunikasi Interpersonal, dan Etika Komunikasi dalam Masyarakat
Authors: Constantin Natasha , Setijadi Naniek
Published: January 2024

Currently, technology is rapidly increasing advancing and developing. Communication technology, especially smartphones, has experienced rapid development with up-to-date technologies and features attached. Amidst the rapid development of technology and features attached to communication tools, the phubbing phenomenon has emerged which occurs at almost all levels of society. The emergence of this phenomenon become one of the developments of communication technology especially cell phones negative impacts, which results in the disruption of relationships between individuals due to too much focus on cell phones. This phenomenon has a bad impact on technological developments and hurts phubbers mental health. literature reviews or desk research. The aim is to provide a comprehensive knowledge of the phubbing phenomena, which is happening unintentionally in society, by drawing on prior research. This article’s purpose is to provide a comprehensive understanding of phubbing and its effects on communication and mental health in society. The goal is to raise awareness and propose preventive measures to mitigate any additional adverse consequences. The findings of this paper demonstrate that the phubbing phenomenon is a negative consequence resulting from the quick and substantial advancements in technology. In Indonesian society, the phenomenon of phubbing is not widely recognized. From the standpoint of communication ethics, this phenomenon is clearly the opposite of face-to-face communication norms and ethics, as it involves disregarding the individual with whom one is conversing. Ultimately, comprehensive community involvement and extensive study are essential to gain a deeper understanding and develop proactive strategies to address the rise of the phubbing phenomena.
Psychopoetic Encounters: Figurations of Difficulty
Authors:   ASCA (Amsterdam School of Cultural Analysis), Bal Mieke
Published: January 2024

While going through some cultural expressions in texts and images, this article proposes reflections on ways in which the practice of poetics, in the sense of creative making, needs to encounter, address, and overcome difficulty in order to facilitate the contribution of the imagination and the acts of “imaging” it allows, to the figuration of the new. Encounter is the key word, indicating plurality and process. Nothing is fixed; hence, not “identity” as something permanent, but instead, in the encounter, identification with others, other fields, other ideas, other images becomes appealing and possible.
In the painstaking attempts to think up new ideas, one encounters difficulty, which needs to be overcome. Only through encounters this becomes thinkable, and that makes imaging something so far unheard of, possible. The ‘poetic’ side of psychopoetics, making through (as traversing) and with (as its material) the reflections emanating from the unconscious as they appear at the edge of consciousness, is what binds together the different disciplines as we know them, in a knot of creativity, imagining, and thinking what we did not know.
Freud and the Topos of the Wandering Jew
Authors:   The Hebrew University of Jerusalem, Barzilai Shuli
Published: January 2024

The question that initiated this investigation concerns Sigmund Freud’s inability to bring himself to leave Vienna during the years before and, then, the days after the Nazi annexation and invasion of Austria in March 1938. Why did Freud delay the decision to escape until it was almost too late? To try and understand such near-fatal immovability, my essay explores two models of mobility: the first is the convoluted folktale, legend, or chronicle of the Wandering Jew; the second is what I call ‘Freud’s train connections’, that is, his theoretical thinking about and personal experience of trains and railroad journeys. However, since Freud’s encounters with the Wandering Jew and his train connections intersect at several junctures, my discussion does not (and indeed cannot) keep them strictly or neatly apart.
Psychoanalytic Readings in Troubled Times: Review of Camden Vera J., ed. The Cambridge Companion to Literature and Psychoanalysis. Cambridge: Cambridge University Press, 2022
Authors:   New Europe College – Institute for Advanced Study in Bucharest; Babeș-Bolyai University, Waysband Edward
Published: January 2024

This is a review article of Vera J. Camden’s edited Cambridge Companion to Literature and Psychoanalysis, which engages critically with the contributors’ main ideas and connects this volume with contemporary events.
GAS LIFTING FOR PRODUCTION OPTIMIZATION USING EXTRA-HIGH-PRESSURE (XHP) GAS FROM NATURAL GAS WELLS WITHOUT COMPRESSION
Authors:   Department of Petroleum Engineering, Federal University of Petroleum Resources, Effurun, Nigeria, Ofesi Felix Samuel , Okologume Chinedu Wilfred ,   Department of Petroleum Engineering, Federal University of Petroleum Resources, Effurun, Nigeria, email: okologume.wilfred@fupre.edu.ng, Morenikeji Benjamin Adediran ,   Department of Mineral and Petroleum Engineering, Yaba College of Technology, Lagos State, Nigeria
Published: January 2024

Artificial lift techniques are used when reservoir pressure drops below the fluid hydrostatic column weight in the well. A compressor station supplies high-pressure gas for the gas lift system, which includes a gas distribution manifold, gas lift lines to the well heads, and gas lift valves. Gas lift has many benefits, but the source of gas and the number of compression stages needed to lift reservoir fluid to the surface are major drawbacks. This paper critically examined this drawback and found a steady source of high-pressure gas that eliminates the need for compression. This study used PROSPER to determine the depths at which gas lift valves will be installed, the maximum gas injection rate of 0.81761 MMscf/day, the maximum oil production rate of 1183.4 STB/D, and the best valve type. Although the extra-high pressure gas (XHP) gas pressure needed to be reduced to properly aerate the fluid hydrostatic column as the gas lift valves (GLVs) opens, this pressure reduction (gas expansion) caused gas cooling/freezing, which is a critical concern on the lift gas path. Therefore, a heat exchanger and water bathe heater preheated the XHP gas to reduce the J-T phenomenon and ensure flow.
INTELLIGENT ACCESS SECURITY SYSTEM
Authors:   Petroleum-Gas University of Ploiesti, Romania, e-mail: gbucur@upg-ploiesti.ro, Dinca Antonio Costin , Craciun Alexandru ,   Petroleum-Gas University of Ploiesti, Romania
Published: January 2024

For any person, company or institution, to secure goods, data, information, different methods were sought and thus the idea of access control appeared. Access control can be done by mobile phone, PIN code, access cards and, perhaps, the most secure way, the biometric feature. Once this idea appeared, it was also desired to automate access, in addition to securing it, and thus, the concept of an access control system appeared. These systems are used on a large scale, both in the public and in the private sector, because they ensure the improvement of the level of protection. This work aims to present a fingerprint-based access control system and the steps that are the basis of its implementation, starting from the block diagram, the functional specifications, the electrical diagram and up to the improvements made to the microcontroller program in the system component.
AN APLICATION FOR THE SELECTION AND SIZING OF CONTROL VALVE FOR CONTROL LOOP
Authors:   Petroleum-Gas University of Ploiesti, Romania, email: ceftene@upg-ploiesti.ro, Popa Cristina
Published: January 2024

The paper presents the research of the author in developing an application for sizing and selection of control valves for typical process control applications. The proper sizing, selection, installation, and maintenance of control valve are all significant to obtain precise control performance.
The paper has three parts. The first part describes the steps necessary to size and selection control valve based on the specific standards. The second part is destined to present the application developed by the author using Python programming language. In the last part, the author has presented and analyzed the numerical results of selection control valve using data from a real process.
THE INFLUENCE OF THE APPLICATION OF ELECTRICAL DESORPTION ON SOIL NUTRIENT CONTENT
Authors:   Petroleum-Gas University of Ploiesti, Romania, email: mpopa@upg-ploiesti.ro, Popa Maria
Published: January 2024

Checking the nutrient content of the soil after applying a depollution method has a significant impact on the environment. Of the macroelements present in the soil structure, those of particular interest are nitrogen, phosphorus and potassium. The presence of each element in the soil structure is important for plant growth on depolluted soils. Nitrogen absorbed from the soil is transformed through various chemical reactions into assimilable amino acids that ensure the growth of leaves, stems and the development of the plant root system. Phosphorus, assimilated by plants in the form of phosphoric acid or phosphoric anhydride, is involved in the functioning of the immune system, increasing the plant's resistance to crop conditions, atmospheric conditions, pest attack and insecticide administration. Potassium is converted during chemical reactions into potassium hydroxide and assimilated in this form by the plant. It increases the plant's ability to store nutrients in its reserve organs. Electrical desorption remediation is recommended as a remediation method for soils contaminated with volatile or semi-volatile compounds. The extraction yield of pollutants from soil is around 95%, lower values are only obtained if the mass content of pollutants in the soil is higher than 10%.
Following the application of desorption depollution, the only element that does not undergo transformation is potassium, which makes this method of depollution preferred, despite being expensive.
AN ANALYSIS OF INFORMATION SEARCH AND RETRIEVAL TECHNIQUES
Authors:   Petroleum-Gas University of Ploiesti, Romania, email: ocangea@upg-ploiesti.ro, Cangea Otilia
Published: January 2024

The informational growth dramatically changed the standard form of publication, access, and use of scientific information. Due to Internet, scientific publications migrated from the traditional to a digital configuration. Common users, as well as highly trained professionals from various fields, aim to retrieve information in the shortest possible time, but in the context of an unprecedented growth of data volume, big difficulties occur in finding and accessing the available information, resulting in stress and important delays in decision making. Therefore, training courses in information culture are organized in university libraries, particularly for a superior efficiency of scientific data bases usage. The paper presents an introduction to the architecture of a retrieval information system and a study of the most popular search engines and of the indexing process. Hereinafter, a Page Rank algorithm implementation is performed and a comparative study relative to different search engines is conducted, emphasizing the specific advantages and disadvantages.
QUANTITATIVE ANALYSIS OF WELL PRODUCTION BY POETTMANN AND CARPENTER CORRELATION AND CHOICE OF AN ACTIVATION MODE. CASE OF THE KINKASI-C1 WELL IN THE KINKASI FIELD
Authors:   University of Kinshasa, Faculty of Petroleum, Gas and New Energies, DR Congo, Corresponding author: olivier.kimpesa69@gmail.com, Kimpesa Dyese Olivier , Benge Kade Altesse ,   University of Kinshasa, Faculty of Petroleum, Gas and New Energies, DR Congo, Matamba Jibikila Raphaël ,   University of Kinshasa, Faculty of Petroleum, Gas and New Energies, DR Congo, Kaseba Mbuyi Symphorien ,   University of Kinshasa, Faculty of Petroleum, Gas and New Energies, DR Congo, Nzambe Keila Kelly ,   University of Kinshasa, Faculty of Petroleum, Gas and New Energies, DR Congo, Kalemba Ngungi Emmanuel ,   University of Kinshasa, Faculty of Petroleum, Gas and New Energies, DR Congo, Tshimanga Kamba Grace ,   University of Kinshasa, Faculty of Petroleum, Gas and New Energies, DR Congo, Munene Asidi Djonive ,   University of Kinshasa, Faculty of Petroleum, Gas and New Energies, DR Congo
Published: January 2024

With a strong focus on optimizing the performance of a producing well, our work performs a nodal analysis of the subsurface production subsystem. Using data from the Kinkasi-C1 well on the Kinkasi field, producing in the Vermelha, it analyses the elements of this subsystem, focusing on the analysis of head losses in the production tubing. Knowing the daily production rate and having determined the inflow performance relationship (reservoir pressure and physical properties of the fluids), the wellhead pressure that was lacking was determined. Starting from the pressure node at the bottom of the well, the Poettmann and Carpenter correlation provided us with the head losses along the tubing and, in turn, the wellhead pressure for the company's daily flow rate. Given that this correlation requires tedious calculations, we used Java programming to develop software to support its calculation algorithm. After this stage, the possibility of producing more with or without activation was studied. By prioritizing oil production, activation by pumping, more specifically using an ESP, was the appropriate means of optimizing KK-C1's performance.
HYDRODYNAMIC LOADS ON AN OFFSHORE WIND TURBINE IN THE ENVIRONMENTAL CONDITIONS OF THE BLACK SEA
Authors:   Petroleum-Gas University of Ploiesti, Romania, email: mmarcu@upg-ploiesti.ro, Marcu Mariea
Published: January 2024

In the current context of promoting the large-scale use of renewable energy, the installation of wind turbines in the offshore and onshore environments is opportune. According to statistics, in 2022 offshore wind installations generated 21 GW, respectively 22.3% of a total of 94 GW produced by all offshore and onshore wind installations. This contribution was, also, estimated to increase in the coming years. In the Romanian sector of the Black Sea, the first wind farm will be installed in four years, according to the Romanian Ministry of Energy. Therefore, in our paper, we start with a short presentation of the different support types of the offshore wind turbine. According to the specialized literature, we found that the monopile has the simplest construction and is the most used in water with a depth of less than 50m. Further, we show theoretical aspects regarding the wave parameters and kinematics, wave spectra, wave forces, and overturning moments that act on a monopile in different conditions. Based on a Black Sea dataset and working scenarios, we performed several sensitivity studies on wind turbine support dimensions, wave characteristics, wave forces, and overturning moments. Finally, the variation ranges of wave forces and overturning moments will be estimated, under the environmental conditions of a Black Sea sector for different sizes of a monopile. These are useful in the design of an offshore wind turbine.
STUDY REGARDING THE DISPERSION OF FLUE GASES IN THE ATMOSPHERE
Authors:   Petroleum-Gas University of Ploiesti, Romania, email: loredana.negoita@upg-ploiesti.ro, Negoiţă Loredana Irena
Published: January 2024

This paper deals with the comparative study of the dispersion of some components of flue gases in the atmosphere. Mathematical modelling of the dispersion of pollutants discharged from technological furnaces in refineries is carried out using high-performance software. Thus, taking into account the meteorological conditions and the pollutant concentrations, the level of atmospheric pollution can be determined.
The aim of the paper is to compare the values of NO2 and CO concentrations obtained with the classical Gaussian dispersion model algorithm with the values of pollutant concentrations estimated using the SCREEN View simulation software.
The determinations were made taking into account receivers located at distances of 100 m, 500 m, 2500 m and 5000 m from the emission source, thus it was established at which distance from the source the maximum pollutant concentrations resulted. For atmospheric stability class, A and F (very unstable and stable). For A stability class, the maximum concentrations pollutant resulted at a distance of 500m from the emission source, and for F stability class, the maximum pollutant concentrations resulted at a distance of 2500 m from the emission source.
Both with the classic work methodology and with the SCREEN View software, the concentration values are comparable, this underlines the precision of the software.
Also, with the classic Gaussian modelling algorithm, the maximum height of the smoke plume was calculated. This is higher for stability class A, compared to F.
ANALYSIS OF THE INFLUENCE OF STATIC FREQUENCY CONVERTERS ON POWER QUALITY AND THE EFFECT OF USING ACTIVE FILTERS
Authors:   Petroleum-Gas University of Ploiesti, Romania, email: asavulescu@upg-ploiesti.ro, Săvulescu Alexandru
Published: January 2024

The assurance of the electric power quality and the monitoring of the level of disruptive emissions determine that the problems related to the limitation of electrical disturbances become one of the important concerns of the electrical energy specialists. The paper presents both the results of a laboratory study on how the frequency converters influence the level of voltage and current harmonics at the output of the converters, and the results and conclusions of the measurements that highlight the major improvement brought to the power quality indicators by equipping with an active filter the supply circuit of a high-power electric drive powered by a frequency converter. An important conclusion of the paper is that before making the decision to mount filters to limit the level of distortion, it is necessary to make a careful analysis of the solutions regarding the reduction of distortion even at the level of the disruptive equipment. Only if these measures are not enough, the solution of using active filters, although expensive, is very effective.
Hubungan Dokter dengan Pasien Dalam Bidang Kesehatan
Authors: Waluyo Bing
Published: January 2024

Abstract

The relationship between doctors and patients begins with a vertical, paternalistic relationship pattern, which is based on the principle of father knows best, which gives birth to a paternalistic relationship. The position/position of the doctor and the patient are not equal, namely the position of the doctor is considered higher than the patient, because the doctor is considered to know best about all kinds of diseases and how to cure them, while the patient is considered to know nothing about the disease and he submits it completely to the doctor. Doctors are placed as patrons (protectors) and patients are placed as clients (protected people). Then, in its development, the vertical, paternalistic relationship pattern shifted to a horizontal, contractual relationship pattern. This relationship gives birth to a horizontal contractual legal aspect which is inspanningsverbintenis which is a legal relationship between two legal subjects (patients and doctors) who are of equal status, giving rise to rights and obligations for the parties concerned. This legal relationship does not promise anything (healing or death) because the object of the legal relationship is the maximum effort made by the doctor carefully and with tension based on his knowledge and experience in treating illnesses to cure the patient's illness.

Keywords: Juridical Review, Relationship, Doctor and Patient, Health Sector.

Abstrak

Hubungan antara dokter dengan pasien bermula pada pola hubungan vertikal paternalistik, yang bertolak pada prinsip father knows best, yang melahirkan hubungan yang bersifat paternalistik. Kedudukan/posisi dokter dengan pasien tidak sederajat yaitu kedudukan dokter dianggap lebih tinggi daripada pasien, karena dokter dianggap paling tahu tentang segala macam penyakit dan cara penyembuhannya, sedang pasien dianggap tidak tahu apa-apa tentang penyakit.dan dia menyerahkan sepenuhnya kepada dokter. Dokter di tempatkan sebagai patron (pelindung) dan pasien di tempatkan sebagai klien (orang yang dilindungi). Kemudian pada perkembangannya pola hubungan yang vertikal paternalistik, bergeser menjadi pola hubungan horizontal kontraktual. Hubungan ini melahirkan aspek hukum horizontal kontraktual yang bersifat inspanningsverbintenis yang merupakan hubungan hukum antara dua subyek hukum (pasien dan dokter) yang berkedudukan sederajat, melahirkan hak dan kewajiban bagi para pihak yang bersangkutan. Hubungan hukum ini tidak menjanjikan sesuatu (kesembuhan atau kematian) karena obyek dari hubungan hukum itu berupa upaya maksimal yang dilakukan oleh dokter secara hati-hati dan penuh ketegangan berdasarkan ilmu pengetahuan dan pengalamannya dalam menangani penyakit untuk menyembuhkan penyakit pasien.

Kata Kunci: Tinjauan Yuridis, Hubungan, Dokter dengan Pasien, Bidang Kesehatan.
Eksekusi Putusan Pengadilan Dalam Perkara Perdata Di Pengadilan Negeri Purwokerto Kelas 1B
Authors: Priyadi Aris
Published: January 2024

Abstract

Court decisions must be enforceable or enforceable. Court decisions are meaningless if they cannot be implemented. Therefore, the judge's decision has executorial power, namely the power to carry out what is stipulated in the decision, either voluntarily or under coercion by state instruments. Execution is the implementation of a court decision that has obtained permanent legal force (in kracht van gewijsde) which is carried out by force because the losing party in the case does not want to fulfill/obey the implementation of the court decision voluntarily. There are two forms of execution when viewed from the target to be achieved by the legal relationship stated in the court decision, namely actual execution and execution of payment of a sum of money. Purwokerto District Court Class 1 B, in the event that the execution has gone through an execution procedure.

Keywords: Execution, Court Decision, Civil Case

Abstrak

Putusan pengadilan harus dapat dilaksanakan atau dijalankan. Suatu putusan pengadilan tidak ada artinya apabila tidakdapat dilaksanakan. Oleh karena itu putusan hakim mempunyai kekuatan eksekutorial, yaitu kekuatan untuk dilaksanakan apa yang ditetapkan dalam putusan baik secara sukarela maupun secara paksa oleh alat-alat negara. Eksekusi merupakan pelaksanaan putusan pengadilan yang telah memperoleh kekuatan hukumtetap ( in kracht van gewijsde) yang dijalankan secara paksa oleh karena pihak yang kalah dalamperkara tidak mau memenuhi/mematuhi pelaksanaan putusan pengadilan secara sukarela. Ada dua bentuk eksekusi apabila ditinjau dari sasaran yang hendak dicapai oleh hubungan hukum yang tercantum dalam putusan pengadilan, yaitu eksekusi riil dan eksekusi pembayaran sejumlah uang. Pengadilan Negeri Purwokerto Kelas 1 B, dalam hal pelaksanaan eksekusi telah melalui prosedur eksekusi.

Kata Kunci: Eksekusi, Putusan Pengadilan, Perkara Perdata
ASSOCIATION OF THE HEMOSTASIS GENE POLYMORPHISMS WITH CLINICAL AND LABORATORY FINDINGS IN PATIENTS WITH MYOCARDIAL INFARCTION
Authors:   Republican Scientific and Practical Center “Cardiology”, Minsk, Belarus, T. S. Koroleva , A. G. Bulgak ,   Belarusian Medical Academy of Postgraduate Education, Minsk, Belarus, I. B. Mosse ,   The Institute of Genetics and Cytology of the National Academy of Sciences of Belarus, Minsk, Belarus, N. G. Sedlyar ,   The Institute of Genetics and Cytology of the National Academy of Sciences of Belarus, Minsk, Belarus, O. V. Zotova ,   Republican Scientific and Practical Center “Cardiology”, Minsk, Belarus
Published: January 2024

The article presents the analysis of the association between polymorphic variants of the FGA, FGG, F2, F5, F11, F13, PAI-1, and GP6 genes and clinical, instrumental, and laboratory data in patients with myocardial infarction from the Republic of Belarus. It has been demonstrated that in patients with myocardial infarction, there exist statistically significant correlations between polymorphic variants of the genes F11 (rs2289252 and rs2036914), F13 (rs5985), F5 (rs6025), PAI-1 (rs1799889), FGG (rs2066865), and a variety of laboratory values and functional indicators of the myocardium. A comprehensive analysis of the genetic component (DNA polymorphism) and the outcomes of dynamic follow-up of the patient in hospital enable clinicians to accurately assess potential hazards of the occurrence and unfavorable progression of a number of diseases including myocardial infarction.
PROGNOSTIC SIGNIFICANCE OF INDICATORS OF THE DYNAMICS OF TROPONIN I CONCENTRATION AFTER OFF-PUMP CORONARY BYPASS GRAFTING AND HYBRID MYOCARDIAL REVASCULARIZATION
Authors:   Minsk Scientific and Practical Center of Surgery, Transplantology and Hematology, Minsk, Belarus, A. Charniak , K. Rubakhov ,   Minsk Scientific and Practical Center of Surgery, Transplantology and Hematology, Minsk, Belarus, A. Ostrovsky ,   Minsk Scientific and Practical Center of Surgery, Transplantology and Hematology, Minsk, Belarus
Published: January 2024

Objective. To assess the prognostic significance of dynamic indicators of troponin I concentration after off-pump coronary artery bypass grafting (CABG) and hybrid myocardial revascularization (HMR) and identification of factors influencing the development of postoperative complications. Methods. The prospective single-center randomized comparative study included 180 patients with multifocal coronary artery disease. Group 1 (n = 98) consisted of patients who underwent off-pump CABG. Group 2 (n = 82) included patients who underwent hybrid myocardial revascularization. HMR consisted of two stages. The 1st stage was minimally invasive direct mammary coronary bypass grafting with access through a left minithoracotomy. The 2nd stage, 1–3 days after the open surgery, was percutaneous coronary intervention using drug-eluting stents. Results. The highest concentrations of Tn and AUC Tn after CABG are characteristic of patients with a peak content of the cardiac marker in the bloodstream 24 hours after surgery, which indicates a longer and more intense release of it into the bloodstream after surgery. Prognostically unfavorable for patients who have undergone CABG is an increase in the concentration of Tn by 12 hours after surgery (Tn 12in /Tn in ) by 68 times or more. Patients with Tn 12 /Tn in ≥ 68 have a sharply reduced event-free survival within 12 months after CABG (p = 0.001). Patients with a combination of Tn 12 /Tn in ≥ 68 and a late peak Tn concentration are at high risk of adverse clinical outcomes after CABG. A high level of Tn by 24 hours after breast cancer is associated with impaired carbohydrate metabolism: the presence of type 2 diabetes (r pb = 0.41), BMI (r pb = 0.33), preoperative concentrations of glucose (r pb = 0.35) and glycated hemoglobin (r pb = 0.41). Prognostic criteria for a Tn concentration of more than 0.2 ng/ml by 24 hours after breast cancer are the presence of CKD and the number of stented arteries in patients with elevated levels of glycated hemoglobin. Conclusion. With unidirectional changes in the concentration of highly-sensitive Tn I after CABG and HMR, a less pronounced release of the cardiomarker into the bloodstream in patients after HMR indicates less myocardial trauma during hybrid myocardial revascularization.
PREDICTION OF ADVERSE CLINICAL OUTCOMES IN PATIENTS WITH CARDIOGENIC SHOCK AFTER OPEN HEART SURGERY WITH INTRA-AORTIC BALLON CONTRAPULSATION
Authors:   Scientific and Practical Center Cardiology, Minsk, Belarus, R. Yarosh , L. Shestakova ,   Scientific and Practical Center Cardiology, Minsk, Belarus, Y. Ostrovsky ,   Scientific and Practical Center Cardiology, Minsk, Belarus
Published: January 2024

Aim. To determine preimplantation risk factors and predictors of unfavorable outcome in patients with cardiogenic shock after open-heart surgery, who had an intraoperative system of mechanical circulatory support – intra-aortic balloon contrapulsation. Methods. A retrospective study was conducted at the Republican Scientific and Practical Center “Cardiology” for 2015–2020. It included 66 patients who underwent heart surgery on bypass and who intraoperatively developed cardiogenic shock, refractory to drug therapy, which resulted in the use of intra-aortic balloon counterpulsation. The diagnosis of cardiogenic shock was determined based on the generally accepted criteria, as well as based on the SCAI (Society for Cardiovascular Angiography and Interventions) classification of shock: systolic blood pressure < 90 mmHg for > 30 minutes or the need for infusion of vasopressors or inotropes to achieve the blood pressure of ≥ 90 mm Hg. The Pearson Chi-square test used for nonparametric analysis of qualitative characteristics. The predictors were identified based on logistic regression. Differences were considered significant at p < 0.05 (5%).Results. Risk factors for adverse outcome in case of CS before the use of IABP were: age over 65 years OR = 6.04 [95% CI 1.73 – 21.06], p = 0.003; female gender OR = 3.24 [95% CI 1.064 – 9.873], p = 0.048; vasoactive and inotropic support of more than 42 points OR = 7.85 [95% CI 2.33 – 26.45], p = 0.001; blood lactate of more than 4.7 mmol/l OR = 4.12 [95% CI 1.27 – 13.37], p = 0.014; blood acidity pH < 7.33 OR = 6.34 [95% CI 1.97 – 20.37], p = 0.003; base deficit BE > –5.6 OR = 7.32 [95% CI 2.19 – 24.42], p = 0.001. According to the β-coefficients of the logistic regression equation, predictors were scored as follows: age > 65 years = 2 points, VIP > 42 = 2 points, lactate > 4.7 mmol/L = 1 point. The cumulative probability of 30-day mortality was as follows: 9% when defined as 1 point, 20% – 2 points, 55% – 3 points, 60% – 4 points, 75% – 5 points (Chi-square 24.1; df = 5; p = 0.001). Conclusions. Cardiogenic shock is a fatal complication in cardiac surgery. The use of vasopressor and inotropic drugs has an important role in the treatment of CS; however, escalation of catecholamine doses leads to the progression of multiple organ failure due to hypoperfusion and hypoxia of target organs. Therefore, the use of intra-aortic balloon counterpulsation can improve the results of CS treatment. However, the effect of IABP is limited to increasing cardiac output by no more than 1 l/minute. Based on the calculator we developed, when determining a high risk of an unfavorable outcome of the IABP use, options for circulatory support should be considered including extracorporeal membrane oxygenation, ventricular assist device.
ROLE OF RHYTHMIC ORGANIZATION OF BIOLOGICAL SYSTEMS IN THE ARISE AND COURSE OF CARDIOVASCULAR DISEASES
Authors:   Belarusian State Medical University, Minsk, Republic of Belarus, I. N. Semenenya , V. A. Pereverzev ,   Belarusian State Medical University, Minsk, Republic of Belarus
Published: January 2024

The article substantiates the essential role of natural physical cosmoplanetary fields, in particular, those associated with the Moon, in the regulation of life processes in biological systems of any level of organization, including humans in normal and in various diseases. The results of studies demonstrating changes in several physiological and biochemical parameters of the human body in different phases of the lunar cycle are presented.The possible molecular and cellular mechanisms through which the influence of the Moon on terrestrial processes can be realized are generalized. The literature data indicating the existence of interrelations between the phases of the lunar cycle, the occurrence and course of acute disorders of coronary and cerebral blood flow, acute aortic dissections and some other cardiovascular diseases are presented. The expediency of considering the phases of the lunar cycle and other cosmic factors in the organization of medical care for patients of cardiotherapy and cardiac surgery is indicated.
A MEDICAL CASE OF BIVENTRICULAR ARRHYTHMOGENIC CARDIOMYOPATHY ASSOCIATED WITH A MUTATION IN DSG2 GENE
Authors:   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, E. A. Zavaley , I. A. Grebeniuk ,   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, E. K. Kurlyanskaya ,   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, A. A. Efimova ,   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, A. M. Troshyna ,   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, V. S. Khudnitskaya ,   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, O. G. Shatova ,   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, T. A. Dubovik ,   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, L. V. Rachok ,   Belarussian State Medical University, Minsk, Republic of Belarus, N. N. Chakova ,   State Scientific Institution The Institute of Genetics and Cytology of the National Academy of Sciences of Belarus
Published: January 2024

This article describes clinical observation over a patient with a biventricular form of arrhythmogenic cardiomyopathy associated with a mutation in DSG2 gene. The morphological realization of this mutation is associated with fibrous-fat replacement of the myocardium of both ventricles of the heart, which is clinically manifested by the development of life-threatening ventricular arrhythmias and a high risk of biventricular heart failure with a tendency to a progressive decrease in myocardial contractility. The affect on young people of working age, hereditary determinism and an unfavorable prognosis of survival actualizes the importance of diagnostic alertness in the examination of young patients with a clinical picture including ventricular arrhythmias, presyncope, syncope conditions and sudden cardiac death. The main issues of diagnosis, criteria for diagnosis in accordance with the Padua criteria (2020), current principles of treatment and prevention of sudden cardiac death are considered.
ISSUES OF OUTPATIENT DIAGNOSIS OF ACUTE CARDIAC REJECTION IN A PATIENT WHO UNDERWENT ORTHOTOPIC HEART TRANSPLANTATION
Authors:   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, I. A. Grebeniuk , E. K. Kurlyanskaya ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, T. V. Osmolovskaya ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, T. V. Rusak ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, E. A. Zavaley ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, A. M. Troshyna ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, T. A. Dubovik ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, V. S. Khudnitskaya ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, L. V. Rachok ,   Belarussian State Medical University, Minsk, Republic of Belarus, Y. A. Veras ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, I. V. Kopytok ,   Outpatient Clinic № 26, Minsk, Republic of Belarus
Published: January 2024

An acute cardiac transplant rejection is a reaction of the recipient’s immune system, which includes the cellular and/or humoral pathway of the immune response. This reaction is directed against the tissues of the “alien” donor organ. The alertness of clinicians regarding the possible development of an acute rejection reaction during the first year after heart transplantation is due to the extremely high risk of developing life-threatening conditions mediated by graft dysfunction. These include various cardiac arrhythmias and a progressive decrease in myocardial contractility. In case of untimely diagnosis of this serious complication, the risk of mortality of the patient who underwent orthotopic heart transplantation is extremely high. What changes in clinical, laboratory and instrumental examination parameters at the outpatient stage can help a practicing cardiologist to suspect the presence of an acute rejection reaction of a heart transplant in a patient who has undergone orthotopic heart transplantation? At present, there is no unambiguous answer to this question, and the topic of early detection and prediction of the development of an acute heart transplant rejection reaction is extremely relevant for modern scientific research and is of great practical interest in the field of transplantology and cardiology, in particular.
PHENOMENON OR BRUGADA SYNDROME?
Authors:   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, V. V. Shyshko , D. B. Goncharik ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, L. I. Plashchinskaya ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, V. C. Barsukevich ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, A. R. Chasnoits ,   Republican Scientific and Practical Center Cardiology, Minsk, Belarus, A. V. Zhykh ,   Republican Scientific and Practical Center “Cardiology”, Minsk, Belarus
Published: January 2024

The Brugada syndrome (BrS) is an inherited disorder associated with increased risk of sudden cardiac death (SCD). Despite the rare occurrence of BrS, timely diagnosis and risk stratification are important tasks today. The presence of syncope of arrhythmic origin in conjunction with a spontaneous ECG pattern of BrS type 1 is a reliable indicator of a poor prognosis. Conversely, in the group with non-arrhythmic syncope, there is no increased risk of life-threatening ventricular tachyarrhythmias. However, the etiology of syncope is difficult to determine in 30% of cases. It is known that data obtained using implantable loop recorders can change therapy strategy in 20–36% of patients with BrS with unexplained syncope, what is a factor in stratifying the cardiac risk of sudden death in this group of patients. The article provides a brief overview of the medical literature and illustrates instances of the diagnosis of syncope in a patient with BrS. Modern approaches of diagnosis and treatment of BrS including catheter ablation and gene therapy are discussed. The clinical characteristics of the disease and the data of laboratory and instrumental studies of presented case are given.
NON-ALCOHOLIC FATTY LIVER DISEASE AND CARDIOVASCULAR RISKS
Authors:   Republican Scientific and Practical Center of Cardiology, Minsk, Belarus, K. Antyukh
Published: January 2024

Republican Scientific and Practical Center of Cardiology, Minsk, Belarus N on-alcoholic fatty liver disease is a multifactorial disease with a complicated mechanism development, which is associated with metabolic disorders, the functions of various organs and systems, as well as the occurrence of a number of diseases, in particular atherosclerosis. According to research conducted in recent years, non-alcoholic fatty liver disease is a predictor of adverse cardiovascular events and can act as an independent risk factor for the development of diseases of the circulatory system, regardless of the presence of diabetes mellitus, dyslipidemia or obesity. The purpose of this work is to analyze the published research data on the epidemiology, etiopathogenesis, diagnosis and features of the clinical course of non-alcoholic fatty liver disease in patients with diseases of the circulatory system as well as to characterize the current state of the problem and to determine the direction for further research.
CARDIOVASCULAR RISK IN COMORBID PATIENTS AFTER METABOLIC SURGERY
Authors:   Belarusian State Medical University, Belarus, Minsk, V. Labashova , I. Pateyuk ,   Belarusian State Medical University, Minsk, Belarus, Y. Dydyshko ,   Belarusian State Medical University, Minsk, Belarus, S. Stebunov ,   Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology, A. Kachan ,   Belarusian State Medical University, Minsk, Belarus, M. Yelesina ,   Belarusian State Medical University, Minsk, Belarus, A. Zarqua ,   Belarusian State Medical University, Minsk, Belarus, N. Shpigun ,   Belarusian State Medical University, Minsk, Belarus
Published: January 2024

Cardiovascular pathology is the leading cause of mortality in the world as well as obesity and associated metabolic disorders are one of the main risk factors for the development and progression of cardiovascular diseases. For most obese patients changing lifestyle for a long period of time seems difficult especially in case of comorbidity. Metabolic surgery is currently recognized as an effective way to treat morbid obesity, reducing the incidence and risk of serious consequences of obesity-related diseases. The aim of this article was to evaluate the effect of metabolic surgery on cardiovascular events and other associated conditions in obese patients. The article provides up-to-date information on modern surgical interventions (gastric bypass, sleeve gastrectomy, mini-gastric bypass and gastric banding). We represent data on the effectiveness of metabolic surgery in obesity, hypertension and dyslipidemia. The effect of bariatric surgery on the remission of type 2 diabetes mellitus is also discussed.