bluuebunny/crossref_metadata_2025 huggingface dataset:
Decanulación exitosa en pacientes con COVID-19
Authors: González-Ramos Daniela , Zúñiga Jubel David , Restrepo Diana , Castillo John James , León Hoover
Published: December 2022

Introducción. Los pacientes con Covid-19 tienen el riesgo de presentar síndrome de dificultad respiratoria aguda, por lo que pueden requerir ventilación mecánica y traqueostomía. De este modo, la decanulación es un proceso importante que está a cargo del equipo rehabilitador.
Objetivos. Describir y caracterizar el proceso de decanulación en pacientes traqueostomizados con COVID-19 para identificar posibles factores que influyen en su realización exitosa.
Métodos. Estudio descriptivo transversal realizado en los pacientes que fueron sometidos a traqueostomía entre junio de 2020 y julio del 2021 en la Clínica de Alta Complejidad Santa Bárbara de Palmira, Colombia. Las variables categóricas se presentaron con porcentajes y para las cuantitativas se contrastó la hipótesis de normalidad a través de la prueba de Kolmogorov-Smirnov.
Resultados. Los pacientes, al momento de ingreso, tenían características de severidad, con un promedio de PaO2/FiO2 de 99,7 mmhg y bloqueo neuromuscular hasta por 20 días; el tiempo promedio de ventilación mecánica fue 17,3 días. A todos los pacientes el equipo de rehabilitación les realizó intervención; de los 15 pacientes incluidos, tres no fueron decanulados. Se realizó un análisis descriptivo de los objetivos y de la interven- ción realizada por cada disciplina; para los tres pacientes no decanulados se analizaron las principales barreras y los predictores del fracaso de una decanulación.
Conclusión. Gracias a la instauración de un plan constante y activo de rehabilitación multidisciplinario en el que los pacientes reciben intervención desde su ingreso hasta su egreso se logró decanular de manera exitosa al 80% de los pacientes traqueostomizados.
Factores asociados a la calidad de vida en adultos con dolor crónico musculoesqueléticoico musculoesquelético
Authors: Fuenmayor Castaño Alexandra , Taborda Holguín Sergio Andrés
Published: December 2022

Introducción. Se estima que una de cada cinco personas en el mundo sufre de dolor crónico y que el dolor musculoesquelético crónico (DMC) es la principal causa de dolor y discapacidad en la sociedad occidental.
Objetivo. Analizar las características sociodemográficas, clínicas y funcionales que influyen en la calidad de vida (CV) de las personas con diagnóstico de DMC.
Métodos. Estudio descriptivo observacional de corte transversal realizado en 101 pacientes con DMC. Se realizó prueba funcional con medición de la prueba de marcha de los 6 minutos, medición de la CV (cuestionario SF-36) y evaluación de la discapacidad (test WHODAS II) y de síntomas de depresión (cuestionario PHQ-9). Se describen características demográficas, clínicas y del estilo de vida.
Resultados. El motivo de consulta más frecuente fue lumbalgia (35,6%), pero también se documentó sensibi-lización central (36,6%) y comorbilidades metabólicas (34,7%) y cardiovasculares (7,8%). El 90% de los pacientes eran sedentarios y el 53,5% obtuvo un desempeño menor a 350 metros en la prueba de marcha de los 6 minutos, o esta debió suspenderse por dolor. En relación con el cuestionario SF-36, las dimensiones relacionadas con mejor CV fueron género femenino, edad entre 34 y 64 años, estado civil casado, estratos socioeconómicos bajo y medio, residencia en zona urbana, nivel educativo secundaria, situación laboral activa, sobrepeso y no consumo de tóxicos.
Conclusiones. El DMC menoscaba la CV de una manera más amplia que el dolor agudo. Según los resultados encontrados, existe relación entre los estilos de vida no saludables y una mala CV; lo anterior es un campo de profundización para nuevos estudios hacia promoción de hábitos saludables, manejo de las emociones y fortalecimiento de habilidades sociales por equipos multidisciplinarios como estrategia de prevención del DMC.
Ataxia espinocerebelosa tipo 10 de inicio tardío
Authors: Leiva Luz Miriam , Zuluaga María Eugenia , Espinosa Katalina , Delgado-Argote Hamilton , Ramirez-Cheyne Julián
Published: December 2022

Introducción. La ataxia espinocerebelosa es un grupo de desórdenes genéticos que consisten en una degeneración progresiva que afecta principalmente al cerebelo, el tronco encefálico y la médula espinal, y se asocia de forma variable con otros síntomas neurológicos.
Presentación del caso. Mujer de 60 años sin antecedentes médicos relevantes, quien consultó al servicio de fisiatría por cuadro clínico de dos años de evolución consistente en alteración progresiva en la marcha, pérdida de fuerza en miembros inferiores, temblor en miembros superiores,  disfagia y fatiga. Al examen físico se encontró disartria leve, disdiadococinesia, dismetría, sacadas hipométricas bilaterales y marcha atáxica. Se realizó resonancia magnética nuclear (RMN) del cerebro que mostró atrofia cerebelosa, y electromiografía y neuroconducciones que confirmó polirradiculoneuropatía axonal. Las pruebas genéticas moleculares evidenciaron expansión de una de una repetición de pentanucleotidos ATTCT, lo que confirmó el diagnóstico de ataxia cerebelosa tipo 10 (SCA10). Se inició manejo multidisciplinario donde fisiatría inició plan de rehabilitación neurológica, manejo del dolor con neuromodulador y prescripción de dispositivo de asistencia para la movilidad tipo caminador. La paciente mejoró su independencia en actividades de la vida diaria: el índice de Barthel pasó de 45 puntos a 75 tras 12 semanas en rehabilitación neurológica.
Conclusión. La SCA10 se consideró inicialmente como una ataxia cerebelosa pura asociada a convulsiones; sin embargo, en los últimos años la identificación de nuevas familias con este desorden ha revelado fenotipos más diversos, incluyendo polineuropatía, signos piramidales y deterioro cognitivo y neuropsiquiátrico. Se describe aquí un caso de SCA10 de inicio tardío (más de 50 años de edad) que podría ser el primero esporádico reportado en Colombia.
IoT industria en Centro América y Caribe
Authors: Muzzio Arguello Javier
Published: December 2022

El objetivo de este artículo es presentar una revisión del desarrollo del internet de las cosas en la Industria en centro América y Caribe, el método que se utilizó para revisar las diferentes partes del proceso que se lleva a cabo en los sectores mencionados fue el analítico, donde se parte de una Tecnología ya madura como es el internet de las cosas y se analiza a nivel de la Industria considerando los últimos adelantos en cuanto la misma ofrece. El material que se utilizó fueron la bibliografía de autores de ediciones referentes al tema y fabricantes que innovan en la industria de las telecomunicaciones, Los Resultados fueron dentro de un análisis profundo que tanto los procesos y como las tendencias vas orientados a fortalecer una Industria que cada vez se perfecciona y se orienta más  a la digitalización y automatización de las partes que permite interactuar hombre -máquina  , esta infraestructura que anteriormente era pasiva ahora se ha vuelto activa gracias a las innovaciones y necesidades de un mercado cada más exigente.
Palaeoanthropological Materials Excavated at the Cemetery of Eski-Kermen (According to 2017 Excavations)
Authors: Radochin Vladimir
Published: December 2022

In 2017, the joint expedition of the Institute of Archaeology of the Crimea of the Russian Academy of Sciences and the History and Archaeology of the Crimea Research Centre of the V. I. Vernadsky Crimean Federal University continued rescue excavations of the site of ancient settlement on Eski-Kermen plateau and the cemetery on the slope of the mountain. The excavation at the cemetery uncovered ten burial constructions from various chronological periods: a burial vault and two undercut graves dating back to the early stage of the ancient town, though seven flat graves date from a later period. The flat graves were found close to the Three Holy Riders’s Church on the slope of Eski-Kermen. This article examines the palaeoanthropological materials obtained from the said burial constructions. The preservation of osseous remains from the undercut graves and burial vault was poor; the materials required preliminary restoration. Studying the materials from the burial vault was impeded since the skeletons were incomplete and osseous material was damaged. The materials from the flat graves were of good and satisfactory level of preservation. Most of the skeletons preserved in complete anatomic order. In investigation determined quantitative and sex-and-age structure of the deceased; the analysis of palaeopathological condition was undertaken; some non-metric features were recorded. Epigenetic peculiarities more often occurred on the cranial bones. The most common diseases among pathological cases were related to the teeth-maxillary apparatus. Diseases of locomotor apparatus occurred on vertebral column and big joints of long bones of arms and legs of mature male individuals. One of the buried female individuals had some changes on the sacrum bones known as spina bifida. There were pathological changes related with iron-deficient conditions, inflammations, and changes of bone tissue in result of overstrain of osseous apparatus due to excessive physical load. Only one case of traumatic lesion was documented. The cleaning of the skeleton from grave 395 uncovered the incompleteness of post-cranial skeleton: it laid in anatomic order, but there were no fibulae.
Bells from the tomb 19/2020 on the Eski-Kermen plateau: composition of the material and reconstruction of the manufacturing process
Authors: Loboda Anastasiya , Antipenko Anna
Published: December 2022

The given article studies two small bells found in the tomb 19/2020 in the narthex of the single-nave church in block II at Eski-Kermen plateau. These bells have slightly flattened body with a slit and a small ball inside; they are decorated with corrugated transverse stripes. One of the bells is completely preserved, the other is fragmented. The aim of the work was to determine the composition of the metal and the manufacturing technology of the bells. The X-ray fluorescence analysis of the elemental composition of the metal of the bells showed that the items themselves and the ball inside one bell were made of tin-lead bronze. All currently known reconstructions of the manufacturing technology of such products are described, with the most possible one as the making of wax model of bells comprising of two halves and, later, lost wax casting; clay form was also lost.
On the Question of the Sacral Centre of Archaic Tyritake
Authors: Zin’ko Viktor
Published: December 2022

The recent years of researches at Tyritake uncovered a number of new results about the Archaic Period in the history of this Bosporan town. The urban structure of Tyritake was created from 540–530 to 480–470 BC. From this period, there are two clearly distinguished stages II-A and II-B, with the border between them as the horizons of two fires and destructions. At stages II-A, the construction of adobe-and-stone residential buildings started in the central area of the town, as well as in its western area with already existing buildings of another purpose around rectangular square. The excavations uncovered numerous storage pits with amphorae and black-slip tableware, as well as ash stains with broken black-figured goblets. The whole area on the western edge of the town was used for all-town sacral purposes and was the western temenos of Tyritake. The western fortification wall of the town was erected ca 520–510 BC, after the first fire; and the layer of the next, second fire, dated to ca 480–470 BC, touches the said wall. The houses and temenos constructed in Tyritake suffered from the second great fire in 480–470 BC. According to the extraordinary sacrificial and sacral complex with four horses (storage pit no. 19), these events ended with some important success of the Tyritake population. The western temenos of Tyritake was active throughout a long period, from 540–530 BC to the turn of the eras.
Pebble Tools from the Terraces of Echkidag Mountain in the Crimea: The Geomorphological and Archaeological Context
Authors: Blaga Nikolai , Zhilin Mikhail , Ruev Vladimir
Published: December 2022

From the mid-1970s on, several findspots supplying archaic pebble tools were discovered in the southern coast of the Crimea. The main feature of all the sites is the absence of cultural layer. According to the dating of ancient sea terraces and the results of comparative typological method, the researchers have dated the said finds of pebble tools from the Oldowan and the Lower Acheulean Periods. The 2019 comprehensive archaeological and geomorphological researches in the southern slopes of Echkidag mountain uncovered that the upper part of the diluvial aprons of the terraces and their surface were younger, with some dating to the modernity, and therefore surface finds cannot be dated according to the positions on this or that level of Echkidag terraces. Moreover, the finds include cultural layers at the site Echkidag 6 containing pebble and flint tools, and hand-made ware. It has been discovered that the pebble tools date from the Neolithic and Bronze Age.
A History of the Preparation of the First All-Russia Population Census of 28 January 1897 in the Crimea
Authors: Borschik Natal'ya
Published: December 2022

This article presents little-known facts about the preparation of the all-Russian Empire population census of 1897. Archival documents revealing the entire spectrum of the creation of census commissions in the Crimean Peninsula have been identified. The Crimean specificity was the simultaneous existence of the provincial census commission in Simferopol and special commissions in the town governments of Kerch and Sevastopol. Their functions, personnel, and specific activities have been analyzed. Specific difficulties that the organizers of the census had to face have been outlined. The conclusion is that careful preparation and implementation of the recommendations from higher authorities contributed to the successful census in the peninsula.
The Mosque in the Village of Sheikh-Koi (Davydovo) According to the Photographs from A. L. Rogach Personal Collection in the Central State Archive of Literature and Art
Authors: Lomakin Dmitry , Aibabina Elena
Published: December 2022

This article addresses the history of researches on the ruined mosque located on the outskirts of the village of Davydovo (Simferopol district, Republic of the Crimea). For the first time this monument called attention in the late 1920s, when a preliminary study was conducted under the supervision of B. N. Zasypkin, and Osman Akchokrakli translated the inscription placed above one of the entrances and showing the date of 1358, which later became the main argument (due to a large number of spoliae, probably erroneous) for a number of researchers to date the construction of the mosque. The main historiographic array of materials comprises of the works of Russian researchers V. P. Kirilko and S. G. Bocharov. They performed perfect architectural analysis of the now-lost cultural heritage site against the background of their field researches and archival materials. The analysis of photographs from the personal archive of the Soviet architect and restorer Aleksandr Lukich Rotach (1893–1990), now residing in the Central State Archives of Literature and Art (St Petersburg), allows a number of important clarifications. The photographs (15 total), mostly taken by B. N. Zasypkin and now introduced to the scholarship, document the exterior and interior of the monument. There are pictures of particular architectural fragments and details, among which the most important for historical and architectural interpretation are those of the minaret, portal, and mihrab. So far, the complex of photograph showing the mosque in the village of Sheikh-Koi from A. L. Rotach’s collection is the only collection of high-quality visual documents uncovering the state of the monument at the last stage of its existence.
Farklı prebiyotik ajanların toz çikolatalı içeceklerin renk ve duyusal özellikleri üzerine etkileri
Authors: OBA İLTER Sirin , YILMAZ Osman
Published: December 2022

Dünyadaki çoğu insan tarafından tüketilen toplam enerjinin %60-70'i nişasta bazlı besinlerden sağlanmaktadır. Beslenme sırasında nişasta miktarını azaltmak için geliştirilen fonksiyonel gıdalarda uygun prebiyotik seçimi ürünlerin duyusal özelliklerini etkilediği için hayati önem taşımaktadır. Bu nedenle geleneksel toz çikolatalı içecek bileşiminde bulunan nişasta gibi hidrokolloidlerin yerine tercih edilen inülin, polidekstroz ve maltodekstrin ile ürün formülasyonunu optimum hale getirmek ürünün renk ve duyusal kalitesinin arttırılabilmesinde önem teşkil etmektedir. Bu amaçla optimizasyonda basit karışım tasarımı kullanılarak üç değişkenli regresyon modelleri oluşturulmuştur. Gerçekleştirilen optimizasyon çalışmasında inülin (0.00, 3.68, 7.66, 11.50, 15.64 ve 23.00 g), polidektroz (0.00, 3.68, 7.66, 11.50, 15.64 ve 23.00 g) ve maltodekstrin oranları (0.00, 3.68, 7.66, 11.50, 15.64 ve 23.00 g) bağımsız değişkenler olarak belirlenmiş olup renk parametreleri (L*, a*, b*) ve duyusal özellikler ise yanıt değerleri olarak seçilmiştir. Çalışmadaki prebiyotik toz çikolatalı içeceklerin b*, pH ve su aktivitesi değerleri sırasıyla 10.33±0.29-12.84±0.20, 7.21±0.08–7.26±0.01 ve 0.293±0.00-0.319±0.00 aralığında tespit edilmiştir. Çalışma sonucunda yapılan duyusal değerlendirmelerde içeceklerin inülin, polidekstroz ve maltodekstrin ile üretilmesi ürünün koku, tatlılık ve genel beğeni değerlerini istatistiksel olarak attırırken renk özelliklerini değiştirmemiştir. Toz çikolatalı içecek formülasyonunda inülin, polidekstroz ve maltodekstrin oranı arttıkça içeceklerin duyusal özelliklerinde iyileşmelerin olduğu görülmüştür. Optimum toz çikolatalı içecek formülasyonunda değişkenler 6.76 g inulin, 12.35g polidekstroz ve 3.89 g maltodekstrin olarak belirlenmiş ve bu bileşen oranları ile kabul edilebilir duyusal özellikleri sağlayan alternatif fonksiyonel içecek üretimi gerçekleştirilmiştir.
Glütensiz unların tekno-fonksiyonel özellikleri ile toz akış davranışlarının belirlenmesi
Authors: ASLAN TÜRKER Duygu , GÖKSEL SARAÇ Meryem , DOGAN Mahmut
Published: December 2022

Bu çalışmada, glütensiz ürünlerin üretiminde sıklıkla kullanılan esmer pirinç unu, kuru fasulye unu, mısır unu, teff unu ve karabuğday ununun toz akış özellikleri ile tekno-fonksiyonel özellikleri değerlendirilmiştir. Örneklerin suda çözünürlük, su ve yağ bağlama kapasitesi, yığın ve sıkıştırılmış yığın yoğunluğu değerleri ile kekleşme, kohezyon ve toz akış hızı bağımlılık (PFSD) testi dâhil olmak üzere bir dizi özelliği ölçülmüştür. Elde edilen sonuçlar mısır unu hariç diğer unlarda kekleşmenin olmadığını göstermiştir. En düşük kohezyon indeksi değeri kuru fasulye ununda gözlenmiş olup bu örnek kolay akış sergilemiştir. Karabuğday unu, teff unu ve esmer pirinç unu kohesif akış özelliği göstermiş, mısır unu ise çok kohesif akış gösteren un grubunda sınıflandırılmıştır. Toz gıdaların taşınması ve işlenmesi gibi çeşitli endüstriyel uygulamaları simüle ettiği için 10, 20, 50 ve 100 mm s-1 akış hızlarında gerçekleştirilen PFSD testi sonucunda glütensiz un numunelerinin akış stabilitesi değerlerinin 0.95 ile 1.04 arasında değiştiği tespit edilmiştir.
The Benefits of ICT Application on the Successful Implementation of Formal Education
Authors: Putrajaya Guntur , Latif Abdul , Nofirman Nofirman , Bangkara B.M.A.S. Anaconda , Maruf Irma Rachmawati
Published: December 2022

This study discussed the problem of the advantages of ICT applications for the successful application of formal learning. We have carefully reviewed some kinds of literature involving a chronological approach, which includes analyzing data, testing data, evaluating and interpreting it until we get some crucial points, which include we get several technological applications, including argumentative reality, adaptive learning, artificial intelligence, robotic and automation, utilization of 5G advances in learning, and learning analytics. It is hoped that these findings will be helpful for further studies.
Individual Peptides Extraction and Characteristics of Cow Colostrum Trypsin Hydrolysate with Biological Activity Assessment
Authors: Tikhonov Sergey , Tikhonova Natalia , Popovskikh Angelika , Tikhonova Maria
Published: December 2022

The research concerned the trypsin peptides analysis of colostrum hydrolyzate. The authors isolated seven individual peptides: TT1, TT2, TT3, T(1), T1.1, T1.2, mpT. They determined the molecular weight of the peptides and the amino acid sequence in the peptide chain by mass spectrometry; peptides – using the international database Protein NCBI. The mpT peptide contains the largest number of amino acids – 49. The T1.2 peptide is similar to the membrane-active peptide BAMA Bos taurus, which opens prospects for its use as a part of antibacterial agents or as a BAS carrier. In colostrum hydrolyzate the T1 peptide has the T highest concentration (2.04 mg/ml). It consists of 17 amino acids and matches the peptide NCI_CGAP_Brn23 cDNA Homo sapiens clone, which is similar to TR: O35085 ARX HOMEOPROTEIN. The homeobox protein containing the development gene of a PRD-like class is related to the T(1) peptide. This gene in humans is located on the X chromosome and is involved in the central nervous system and pancreas development. According to the results, the researchers isolated peptides from colostrum hydrolyzate, and identified some of them. Still a man understudies the biological role of most of the determined peptides, and has not proved its safety. In this regard, the study aimed at assessing the hydrolyzate cytotoxicity using the Neutral Red Assay method on the HEK293 cell line during a 24-hour incubation. Cytotoxicity in the first, second and third measurements at a concentration of 0.1 mg/ml was: −3.3; −1.0 and 0.20; at a concentration of 0.3 mg/ml: −1.3; −3.5 and −8.7; at 0.5 mg/ml: −2.6; −0.6 and 0.4. The results indicate no toxicity. The authors studied the antimicrobial and antifungal hydrolyzate activity. Colostrum hydrolyzate demonstrates antimicrobial activity against E. coli and B. subtilis bacteria and antifungal activity against C. albicans. The results assert that the peptides are of clinical importance and can serve as a template for the anti-infective drug development.
Properties Stability Forecast of Pickering Emulsion Structured by Bioactive Plant Particles
Authors: Potoroko Irina , Kalinina Irina , Paimulina Anastasia
Published: December 2022

The new generation design and production of food systems with the declared physicochemical and bioactive properties is impossible without the use of science-grounded approaches based on a complex combination of experimental studies and quantum calculation algorithms. One of the promising food systems, actively studied by the scientists around the world, are the Pickering emulsions. Pickering emulsions act as an emulsion food products basis and a fortifying complex that can be an effective system for delivering biologically active substances to the human body. The study aimed at obtaining predictive solutions to achieve the properties stability of the Pickering emulsions stabilized by plant sonochemically structured bioactive particles. As a result of applying quantum chemical calculations using the online resource chemosophia.com and visualization programs, the authors obtained a stable molecular interaction complex between a lipophilic biologically active substance and linseed oil triglyceride, confirming the possibility of such composite development. As a procedure result for fucoidan biologically active substance depolymerization using ultrasonic low-frequency exposure, there was a reduction in the fucoidan particles size by 20-40 times. This led to an increase in its stabilizing properties in the Pickering emulsion based on linseed oil. The scanning electron microscopy results enabled to reveal that the biologically active stabilizer concentration of the Pickering emulsion occurred at the phase boundary predominantly. The resulting Pickering emulsions can act as the basis of emulsion food products enriched with the valuable fatty acid composition of linseed oil and biologically active substances used to stabilize the emulsion.
Thermal Parameters Measurement of Carp Caviar as a Freeze Object and a Lecithin Source
Authors: Polikarpova Violetta , Aleksanian Igor , Arabova Zarema , Nugmanov Albert , Elmurzaev Ayub
Published: December 2022

Increasing the raw materials deep processing efficiency for commercial fish farming, including freshwater fish caviar of the carp family that demonstrates low demand on the Russian market, is an important and urgent task. In the modern context, Russian food industry needs high quality natural emulsifiers, for example, lecithin. The research aim is to determine the thermophysical characteristics, cryoscopic temperature, refrigeration object density and the amount of frozen moisture in it, depending on its temperature variation. The study object is carp caviar. A man found the temperature variation during carp caviar freezing using an experimental stand, containing a specialized ThermoChart program for constructing thermograms. The authors determined caviar material density dependence on its temperature in the range from −18 to 5 °C: with an increase in temperature, its density raised to 1,071 kg/m³ monotonously at Tcr = −0.91 °C and then changed up to 5 °C ordinary. An obtained thermophysical characteristics values analysis of carp caviar, which is a high-moisture product, demonstrates that its freezing is accompanied by the latent crystallization heat release, depending on a decrease in the study object temperature and due to the proton bonds presence at the sample microlevel. A man can use obtained data in the freezing processes calculation and refrigeration equipment design; and utilize the semi-finished product to extract lecithin.
Processing of Artichoke Tubers into Distillates for the Original Alcoholic Beverages Production
Authors: Solovyov Alexander , Turshatov Mikhail , Kononenko Valentin , Pogorzhelskaya Natalia , Pavlenko Svetlana
Published: December 2022

Artichoke is a universal crop. A man produces inulin, fructose, and pectin from its tubers industrially. Due to the significant carbohydrate content (up to 20 %) artichoke can be a raw material for the ethyl rectified alcohol production. The research aimed at assessing the possibility of artichoke processing into distillate with its physico-chemical and organoleptic parameters determination and subsequent assessment of its applicability for the original alcoholic beverages production. The artichoke tubers treatment process included grinding, water-heat and enzymatic treatment, fermentation and distillation process. To obtain marketable products, the researchers developed a two-stage distillation scheme on a laboratory unit equipped with a distillation tower with single-cap plates. At the first stage, a man extracted alcohol from a fermented wash to obtain an unrefined distillate with a strength of 20 % vol., at the second stage, strengthened the resulting distillate to 94 % vol. and cleared from related impurities additionally. According to the physico-chemical parameters the distillate samples correspond to the GOST 33723-2016 “Grain Distillate. Technical Conditions”. There were no volatiles unusual for alcoholic fermentation. The professional expert degustators demonstrated the highest regard for the studied distillate samples, they noted the presence of raw materials in the taste and aroma, clothing the product with originality and recognition. The distillate is recommended for the original alcoholic beverage production.
Machine Learning y DataOps
Authors: Bolívar Barón Holman Diego
Published: December 2022

Desde tiempos inmemoriales, los seres humanos han construido máquinas para simplificar su trabajo y reducir el esfuerzo en completar diferentes tareas.
Carbon Border Adjustment Mechanism of the EU and the US: the Impact on South Korea
Authors:   Institute of East and West Studies Yonsei University, Jo Ha-Hyun , Kim SeungWhan
Published: December 2022

This study is to measure the impact of the Carbon Border Adjustment Mechanism by the European Union and the United States on South Korea. Five products of the EU CBAM are selected for this analysis: iron and steel, organic chemicals, plastic, aluminum, and cement. To evaluate the impact, this paper used carbon intensity, export value, and carbon emission price data. The additional burden on the products is expected to cost 531 billion KRW by the EU CBAM implementation. In the case of the US implementation, the additional burden is expected to reach 214 billion KRW when the social cost of carbon(SCC) is used for the carbon price. These estimates are different from the results of previous studies, as the calculation in this study is based on HS codes. In fact, the estimates are larger than previous results, since the gap between carbon prices has grown in recent months. Among products, iron and steel products bear the largest proportion of the burden. However, the influence of the CBAM may become more extensive with an extended range of products and an increased price of carbon emissions. In order to respond to the CBAM effectively, it is necessary for the government to stimulate the de-carbonization of industry and incentivize investment in renewable energy. Corporations are also required to actively invest in low-carbon technologies and improve the capacity for climate change adaptation.
The Determinants of Global Value Chain Participation: Globalization and Economic Development Stages
Authors:   Institute of East and West Studies Yonsei University, Kim Zu Kweon , Choi Leesun
Published: December 2022

One of the recent meaningful changes in the development of globalization can be represented by structural changes in the global production network, such as the establishment, development, expansion, and reorganization of the so-called Global Value Chain(GVC). This study analyzed the determinants of the GVC participation rate by dividing it into the entire period from 2000 to 2019, the stages of globalization(Hyperglobalization and slowbalization), and stages of economic growth(developed and non-developed countries). In all the study periods, trade openness was the only variable that had a significant positive(+) effect on the determinants of the GVC participation rate. And other variables showed different results depending on the stage of globalization or economic growth. The results of this study suggest that the factors that promote or reduce the GVC participation rate differ depending on the stage of globalization or economic growth, so that the government requires to set up appropriate policies according to the global economic environment and the country's economic situation.
Leptospirose no Brasil: aspectos clínico-epidemiológicos. 2007 a 2018
Authors: da Silva Neuder Wesley França
Published: December 2022

A leptospirose é uma doença infecciosa febril, causada por uma bactéria
(Leptospira) sendo um importante problema de saúde pública no Brasil, que em
2015, apresentou maior número de casos na América Latina (40,2%). Assim,
objetivou-se descrever o perfil clínico-epidemiológico de casos confirmados da
doença no Brasil. Destarte, realizou-se estudo descritivo dos casos confirmados
de leptospirose, entre 2007 e 2018, utilizando-se o banco de dados da
leptospirose do DATASUS/MS. Desta feita observou-se 45.213 casos confirmados,
com predomínio da região Sudeste (33,50%) e Sul (32,73%). Cinco estados
apresentaram 52,31% dos casos (SP, RS, SC, PR e AC), com maior incidência no AC
(41,62/100 mil hab.). A média anual foi de 3.768 casos; maior frequência em 2011
(10,99%); no 1º semestre (65,84%); em janeiro (14,06%); no sexo masculino
(79,68%); entre 5ª e 8ª série do EF (16,58%); zona urbana (55,47%); faixa etária
entre 20 e 39 anos (40,52%) e local de infecção domiciliar (40,99%).
Frequentemente diagnosticados clínico-laboratorialmente (86,91%); evolução para
cura (82,98%) e óbitos na maioria no sexo masculino (7,20%). A doença predominou
nas regiões Sudeste e Sul, com prevalência em SP, RS, SC, PR e AC. Incidência
maior no AC; maior frequência em 2011; no 1º semestre; em janeiro; na região
urbana; entre 20 e 39 anos; no sexo masculino, de baixa escolaridade; local de
infecção domiciliar, com diagnósticos clínico-laboratoriais e frequente evolução
para cura, e óbitos mais no sexo masculino.
Análise do bioclima térmico para desenvolvimento de diretrizes de planejamento urbano em cidades tropicais – caso de Goiânia
Authors: Silva Leandro Mendes da , Abreu-Harbich Loyde Vieira De , Matzarakis Andreas
Published: December 2022

O planejamento urbano estratégico desenvolvido a partir de mapas temáticos aponta o potencial para a
inserção de infraestrutura verde na cidade que visa melhoria do bioclima térmico em cidades tropicais
como Goiânia. O desenvolvimento de mapas temáticos com suporte em ferramentas computacionais, tais
como sistemas de informações geográficas (SIG), Multispec e outros, permitem o mapeamento e análise de
áreas urbanas visando a melhoria do conforto térmico, saúde e bem-estar da população em diferentes
áreas da cidade. Neste capítulo apresenta-se a metodologia de análise bioclimática para o desenvolvimento
de diretrizes de planejamento urbano para a adaptação às mudanças climáticas e eficiência energética em
cidades tropicais como Goiânia. Metodologia: a) Caracterizar a área de estudo; b) Desenvolver um mapa
temático de clima urbano baseado nas zonas de clima local (LCZ); c) Quantificar do bioclima térmico e
simulação de cenários futuros com as seguintes diretrizes bioclimáticas: sombreamento arbóreo por
diferentes espécies arbóreas, promoção ou redução da velocidade do vento, e aumento da umidade; d)
Desenvolver de diretrizes de desenho urbano para cada LCZ. Foram identificadas 8 Zonas de Clima Local
(LCZ) a partir do cruzamento de dados como de topografia, altura das edificações, ocupação do lote, relação
altura e largura dos edifícios (H/W), cobertura verde e uso do solo. A partir de dados meteorológicos para o
período de 2002 a 2015, o clima de Goiânia apresentou cerca de 10% da temperatura do ar e 30% das
temperaturas fisiologicamente equivalentes (PET) estão em desconforto térmico ao longo do ano e os
meses de agosto a outubro são os mais desconfortáveis. A promoção de sombreamento arbórea e a
promoção de ventilação urbana por edifícios de multi-pavimentos podem melhorar as sensações de
conforto térmico em ambientes abertos e trazer mais eficiência energética principalmente nos meses mais
quentes. A construção de parques e revitalização de praças aumentar a biomassa de vegetação arbórea e
promover a umidificação. Há um potencial para o aumento do sombreamento arbóreo em todas as LCZs;
promoção de vento nas LCZs 2, 4 e 5; aumento de áreas que umidifiquem tal como criação de parques e
praças com corpos d’água nas LCZs 2 e 3. Esta metodologia permite desenvolver intervenções urbanas
pontuais e eficientes que promovam a inserção de vegetação arbórea e concepção de uma relação entre
altura e largura das edificações favoráveis a ventilação no ambiente.
Conforto Térmico Adaptativo Em Salas De Aula Do Centro-Oeste – Caso Da Cidade De Goiás
Authors: Abreu-Harbich Loyde Vieira de
Published: December 2022

Para entender a relação dos usuários com o ambiente construído foram coletadas respostas sobre a
percepção térmica de estudantes do ensino superior da cidade de Goiás, antiga capital da cidade
homônima. Este estudo tem como objetivo avaliar diferenças entre envoltórios de edifícios (adobe x
tijolo) e sistemas de ventilação (ventilação natural e ar condicionado) e suas influências no conforto
térmico. Foram entrevistadas 400 pessoas sobre as sensações de conforto térmico. Os resultados
mostram que, embora as temperaturas do ar sejam mais elevadas no edifício histórico, as pessoas
estão mais satisfeitas com o ambiente térmico do que no novo edifício com sistema de ar
condicionado.
MANEJO DA DOR NO PARTO : GUIA PRÁTICO DE MÉTODOS NÃO FARMACOLÓGICOS
Authors: Oliveira Priscila Antunes de , Almeida Janaína Marques de , Sena Izabella Vieira dos Anjos , Moraes Liliane Rezende de , Caldeira Nélia Cristiane Almeida
Published: December 2022

A dor no trabalho de parto pode ser compreendida como uma experiência subjetiva e complexa, acompanhada de um componente psicológico variável entre as mulheres, sofrendo influências de fatores culturais, étnicos, sociais e ambientais. Este guia tem como objetivo fornecer subsídios baseados em evidências científicas para qualificação da equipe no manejo dos métodos não farmacológicos para o alívio da dor no trabalho de parto e contribuir para uma assistência mais humanizada, incentivando o parto normal. Mulheres em trabalho de parto devem ser tratadas com respeito, ter acesso às informações baseadas em evidências e serem incluídas na tomada de decisão. Existem vários métodos disponíveis para ajudar uma parturiente a lidar com a dor no parto e ter uma experiência positiva. O conhecimento sobre a aplicação de métodos de alívio da dor pode favorecer a melhoria dos cuidados e definir estratégias de cuidados para para atender às necessidades específicas de cada parturiente.
DESMISTIFICANDO A CIRURGIA CARDÍACA
Authors: Saruhashi Caroline Harumi Sericawa , Fernandes Cecília Dias , Cruz Diogo Kelton Dias da , Teixeira Ester Camargo , Amorim Flávia Mari , Vilhena Gleyce Kelly Setubal , Pinheiro Ingrid Cristhine , Oliveira Laura Guimarães de , Campos Letícia Lima , Madeira Maikon
Published: December 2022

"Desmistificando a Cirurgia Cardíaca" é fruto da vontade de estudantes de medicina do Brasil inteiro de democratizar o acesso à informação de qualidade em ciência. Juntos de nosso mentor, o médico cirurgião geral Maikon Madeira, preparamos esse e-book pensando em orientar qualquer pessoa que precise passar por uma cirurgia cardíaca, explicando como ocorre o processo desde sua indicação, até sua recuperação.
WITTGENSTEIN Y LOS DESACUERDOS MORALES: SOBRE LA JUSTIFICACIÓN MORAL Y SUS IMPLICACIONES PARA EL RELATIVISMO MORAL
Authors: Fairhurst Chilton Jordi
Published: December 2022

Este artículo estudia las observaciones tardías de Wittgenstein sobre los des-acuerdos morales. Primero, examina las prácticas de justificación y dar razones en los desacuerdos morales. Argumenta que, para Wittgenstein, las razones morales son descripciones que se utilizan para justificar una evaluación moral. Segundo, explica que la idoneidad y el carácter concluyente de las razones y justificaciones morales dependen de su atractivo para quienquiera que se pre-senten, no de cómo es el mundo. Tercero, muestra que las observaciones de Wi-ttgenstein sobre el carácter inconcluyente de las razones y justificaciones mora-les no implican un compromiso con el relativismo moral. Finalmente, muestra como las observaciones de Wittgenstein pueden usarse en futuras investigacio-nes para desarrollar una nueva imagen de los desacuerdos morales profundos.
Validación de una escala para identificación de peligros ergonómicos en centros de trabajo
Authors: Rodríguez Gámez Iván Francisco , Barajas Bustillos Manuel Alejandro , Maldonado Macías Aidé Aracely , Barrón López Enrique , Naranjo Flores Arnulfo Aurelio
Published: December 2022

En Ciudad Juárez, México, el servicio de transporte público carece de condiciones seguras atribuidas al estado de las calles, a las pobres condiciones de trabajo de los conductores y malas condiciones de los camiones. Esta investigación determina la frecuencia de eventos de violencia en el trabajo, las fuentes de carga mental de los conductores, así como las molestias musculoesqueléticas más frecuentes. La metodología cuenta con 6 fases. En las primeras se realizó una búsqueda bibliográfica y se recolectaron evidencias de eventos de violencia en el trabajo experimentados por los conductores, su estado de salud, accidentes al año y condiciones de las unidades. En la cuarta fase, se implementaron los métodos de Marley y Kumar y NASA TLX. En las etapas finales se determinaron las principales fuentes y el nivel de carga mental, así como las molestias musculoesqueléticas. Se caracterizó a los 27 conductores por su edad, género y tipo de servicio médico. Entre las principales molestias se identificaron mano y muñeca derecha, la espalda baja/media, los ojos y la zona de glúteos. Se detectó que el 22% de los conductores presentaban carga mental alta, el 67% media y el 11% baja, donde la exigencia temporal y física fueron las fuentes de carga más relevantes. Todos los conductores presentaban molestias en alguna parte del cuerpo y algún nivel de carga mental de trabajo. Es necesario más estudios en esta profesión vulnerable por su impacto en la seguridad de los pasajeros, de terceros y de ellos mismos.
Transición del Desarrollo Sostenible a la Sustentabilidad de la Vida
Authors: Vaca L´ópez Andrea
Published: December 2022

En el ámbito académico se encuentran diferentes posturas frente al concepto de sostenibilidad, una manera de agrupar los principales discursos la propone Arturo Escobar (1995) al identificar tres grandes perspectivas: a) Liberal o Desarrollo Sostenible, b) Culturalista o del Límite al crecimiento y c) Ecosocialista. Comprender estos discursos nos conlleva a acciones conscientes en los ámbitos personal, profesional, investigativo, académico, etc., para contribuir a la sostenibilidad según nuestro entorno.
Comparative preference of loans provided by SBI and ICICI with reference to Coimbatore district
Authors: V. Jenifer  , Saran babu. N  , Dharsana. K. S
Published: December 2022

The need for home loans arises not because property prices are heading upwards all the time but because home loans make great sense from a long-term savings perspective. The study is about comparison of service of SBI and ICICI. The main objective of the study is that to know about the socio-economic profile of the respondents availing home loan in SBI and ICICI Bank in Coimbatore city and to study on the customer opinion about services and the problems faced by them. The study was analyzed with descriptive research with 125 samples from ICICI and 125 samples from SBI were percentage analysis, chi square, descriptive statistics and factor analysis were used as tools for analyzing the data. The conclusion is that the service provided by ICICI is better than SBI based on the interest rate and both the banks have to implement new technology to reduce the process time of loans which leads to satisfaction of customers in future period of time.
Local authority in Homa bay, Kenya, during Jomo Kenyatta’s first republic, 1963-1978
Authors: Walter Otieno K’Odipo
Published: December 2022

This paper examines the development of local authority in Homa Bay during the first republic of President Jomo Kenyatta. It has considered the restructuring and rebuilding of the nation, examined the changes that affected civil servants in local authority’s governance, analyzed the provincial administration and the chief’s tenure in Homa Bay, assessed the place of the 1966 Hardacre Commission, investigated development of infrastructures in Homa Bay (1960-66), reviewed the 1969 political crisis, examined the South Nyanza development plans and the role of NGOs in development in Homa Bay. The paper used the structural-functional theory in the understanding of the structures of local authorities’ governance in Kenya. The functioning of a system determines the classification of a system. The methodology was based on qualitative approach whereby data collection was done through purposive sampling and analysis done by coding the responses from participants thematically. The results of this research would inform policy making by the state in matters pertaining to local authority governance and devolution.
Efficacy of hormone therapy on stretched penile length in micropenis: A systematic review
Authors: Okta Margarita Susiana  , Fajar Avicenna  , Reny I’tishom  , Joshua Teofilus Sutadji
Published: December 2022

Background: While there have been clinical studies to prove the efficacy of testosterone in increasing the stretched penile size in cases of micropenis, giving various results, attempts to summarize them have been scant. Objectives: This systematic review summarizes the efficacy of testosterone in the treatment of micropenis. Materials and methods: This systematic review sought original English research articles in which patients with isolated micropenis were administered testosterone to increase their stretched penile length in PubMed, Scopus, and ProQuest. Search keywords were “micropenis” and “hormone”. We then assessed the selected articles using the Joanna Briggs Institute (JBI) Checklist for Case Series. Results: Of the 1,181 articles, 8 articles (n = 171) met the inclusion criteria for this systematic review. Assessment of the articles showed that various hormones are used in the treatment of micropenis. Discussion: Various hormones, mainly testosterone, are effective in treating micropenis. It is found that testosterone, especially topical testosterone, can increase stretched penile length 2 until 3 times the pre-treatment length in 3 months of treatment. However, other hormone treatments can also increase stretched penile length, but its effect is not as significant as testosterone. Dual hormone therapy is also used for micropenis and other hormone deficiencies to increase the efficacy of the results. Conclusions: Hormone therapy is effective in increasing the stretched penile size in cases of micropenis. The use of hormones needs to be tailored to each patient to ensure optimal result.
Analisis Penerapan Pratik Ibadah berdasarkan Putusan Tarjih Muhammadiyah pada Warga Muhammadiyah Kabupaten Sorong
Authors: Anakotta Raisa , Irianti Mustika , A.A. Kadir Aswin
Published: December 2022

Himpunan Putusan Tarjih (HPT) Muhammadiyah berisi hasil-hasil muktamar tarjih yang menyangkut berbagai persoalan mulai dari keimanan, ibadah hingga persoalan yang berkaitan dengan keumatan dan agama Islam. Salah satu identitas dan ciri warga Muhammadiyah adalah berkehidupan sesuai dengan putusan tarjih Muhammadiyah. Hingga saat ini belum ada data maupun informasi terkait seberapa jauh HPT Muhammadiyah telah diimplementasikan dalam kehidupan oleh warga Muhammadiyah di seluruh pelosok negeri. Tujuan penelitian ini adalah untuk melihat pengimplementasian HPT dalam beribadah warga Muhammadiyah di Kabupaten Sorong. Desain penelitian yang digunakan adalah survey dengan metode penjabaran secara deskriptif kuantitatif. Data penelitian akan dianalisis secara statistik yang kemudian akan dijabarkan secara deskriptif untuk memberikan penjelasan lebih terperinci. Berdasarkan aspek pemahaman dan pengetahuan, pelaksanaan, penerapan tata cara dan penerapan bacaan dan doa menunjukkan bahwa warga Muhammadiyah di Kabupaten Sorong telah menerapkan praktik ibadah sesuai dengan yang telah dianjurkan dalam HPT Muhammadiyah. Faktor-faktor yang mempengaruhi warga Muhammadiyah Kabupaten Sorong dalam menerapkan ibadah berdasarkan HPT lebih banyak didominasi oleh faktor latar belakang keluarga dan lingkungan, baik lingkungan pendidikan, lingkungan kerja maupun lingkungan tempat tinggal. Faktor lain yang mempengaruhi adalah usia, pengetahuan, kebiasaan, tidak adanya kewajiban, keringkasan bacaan yang berpengaruh dalam kekhusyu’an beribadah, serta penjelasan yang disertai hadis yang sahih.
Meccanismi comuni tra diabete e declino cognitivo
Authors: Cataldo Vittoria , Scisciola Lucia , Franzese Martina , Puocci Armando , Barbieri Michelangela
Published: December 2022

The increased prevalence of diabetes (DM) constitutes a major public health problem, primarily due to its numerous comorbidity and complications. It is widely demonstrated that DM is a significant risk factor for the development of cognitive impairment. Metabolic diseases can influence cognitive functions through multiple interconnected mechanisms. Cerebral insulin resistance, oxidative stress, neuroinflammation, and neuroendocrine dysfunctions can further the development of neurodegeneration diseases. The identification of the molecular mechanisms involved represents the target for the founding of early potential markers and new therapeutic targets of neurodegenerative diseases.