bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Trial: Precise Administration of Sucralfate Powder in Prevention of Delayed Postpolypectomy Bleeding. A Randomized Controlled Trial
Authors: Chiang Hsueh-Chien , Chen Po-Jun , Yang Er-Hsiang , Kuo Tzu-Ling , Hsieh Ming-Tsung , Kang Jui-Wen , Cheng Hsiu-Chi , Chang Wei-Lun , Chen Wei-Ying , Chiu Hung-Chih , Lin Meng-Ying , Hong Tzu-Chun , Chiang Chien-Ming , Chen Wei-Chih , Huang Kuan-Kai , Lu Meng-Hsuan , Wu Ming-Hsuan , Chen Chiung-Yu , Lin Xi-Zhang , Chuang Chiao-Hsiung
Published: February 2025

INTRODUCTION:

Delayed postpolypectomy bleeding occurs in approximately 1%–2% of all patients undergoing colonoscopic polypectomy, and this rate increases to 6% in patients with large (>2 cm) colon polyps. Sucralfate can protect the mucosa and promote its healing. This study was conducted to investigate whether colonoscopic spraying of sucralfate powder on polypectomy wounds can prevent delayed postoperative bleeding.

METHODS:

This randomized controlled trial included patients with polyps (size ≥0.5 cm) who had undergone colonoscopic polypectomy at our hospital between May 2023 and January 2024. After polypectomy, the patients received standard treatment for immediate bleeding. Then, they were randomly allocated to either a sucralfate group (prophylactic spraying of sucralfate powder [3 g] on polypectomy wounds) or a control group. All patients were monitored for delayed bleeding within 28 days after colonoscopy.

RESULTS:

A total of 160 patients were divided into the sucralfate and control groups (80 per group). The baseline characteristics were balanced between the groups. The rate of delayed postpolypectomy bleeding (0% vs 6.3%, respectively; P = 0.029) and postpolypectomy overt bloody stool (2.4% vs 18.8%, respectively; P = 0.001) were lower in the sucralfate group than in the control group. The duration of freedom from delayed bleeding was longer in the sucralfate group than in the control group (P = 0.024). Multivariate Cox regression analysis confirmed the additional sucralfate spray as an independent factor against postpolypectomy overt bloody stool (relative risk, 0.03; 95% confidence interval, 0.003–0.43; P = 0.009).

DISCUSSION:

Colonoscopic spraying of sucralfate powder is a safe approach with potential to reduce the risk of delayed postpolypectomy bleeding. Trial registration: NCT05817656.
Type 1 diabetes in children: adulthood ahead
Authors: Laptev D. N.
Published: February 2025

Type 1 diabetes mellitus (T1DM) in childhood is one of the most important social and medical problems, given the growing incidence and negative impact on the duration and quality of life. The onset of the disease in childhood associated with significantly reduced life expectancy, largely due to micro- and macrovascular complications, and background pathological processes may occur from the T1DM onset due to suboptimal glucose control. Large registers data indicate that less than half of children with T1DM achieve target glycemic control, and adolescence is characterized by the worst glycemic control among all age groups. In recent years, modern treatment tools have been widely adopted in children with T1DM: insulin pumps, continuous glucose monitoring and automatic insulin delivery systems, which has become possible due to their increased availability, convenience and proven effectiveness. These technologies not only reduce the burden of the disease, but also improve the effectiveness of treatment of T1DM in children, consequently reducing the risks of diabetic complications protecting the health for the upcoming adult life.
Chronic kidney disease in patients with diabetes mellitus: new challenges
Authors: Shamkhalova M. S. , Sukhareva O. Y. , Martynov S. A. , Severina A. S. , Vikulova O. K. , Trubitsyna N. P. , Naumenko O. N. , Zaytseva N. V. , Shestakova M. V. , Dedov I. I. , Mokrysheva N. G.
Published: February 2025

Chronic kidney disease (CKD) is a supranosological concept, defined as a disorder of the structure and/or function of the kidneys for 3 months or more that leads to health consequences. CKD develops in 20–40% of patients with diabetes mellitus (DM). Dynamic analysis of epidemiological indicators of CKD in patients with diabetes mellitus points to the prevalence increase of this pathology in the Russian Federation in 2010–2022. Improved quality of diagnostics of earlier stages complications, a decrease in the risk of cardiovascular events (the leading cause of death) and end-stage renal failure at a later age and with a longer duration of diabetes are noted as well. The development of tools for predicting the risk of the pathology progression and its complications has made it possible to improve patient monitoring and routing. Current international and domestic recommendations emphasize a comprehensive approach to the treatment of CKD, including lifestyle modification, evidence-based pharmacological treatments aimed at preserving organ function, and improving cardiovascular prognosis. An optimal model of care for patients with diabetes and CKD, aimed at multidisciplinary care and adapted according to the severity of CKD, will lead to the best outcomes for the individual patient and society.
Cardiodiabetology: Evolution or Revolution?
Authors: Bondarenko I. Z. , Kalashnikov V. Y.
Published: February 2025

This article addresses contemporary issues in endocrine cardiology. The main content of the work is an analysis of the history of medications used in diabetology, ranging from the first animal-derived insulins to modern sodium-glucose cotransporter 2 inhibitors (SGLT2 inhibitors) and glucagon-like peptide-1 receptor agonists (GLP-1 RA), which possess pronounced cardioprotective activity. Studies demonstrating their effectiveness in influencing the cardiovascular system in patients with type 2 diabetes mellitus (T2DM) are analyzed. Particular attention is paid to multicenter clinical trials that studied the effect of hypoglycemia on cardiovascular outcomes in patients with T2DM. The article also summarizes the scientific and practical experience of using SGLT2 inhibitors in patients with various cardiac arrhythmias, including those that are life-threatening for patients with T2DM.
Of Skin and Bones: Revisiting an Inughuit Dogsled Procured by John Ross in 1818
Authors: Vitale Emma , Grønnow Bjarne
Published: February 2025

During a British expedition to the Arctic headed by John Ross in 1818, a dogsled made of bones was procured from the Inughuit people in Northwest Greenland, hitherto unknown to Europeans. We present a contextual and technological analysis of this, the oldest known dogsled from the Arctic still intact. Our work leads to discovery of a hidden artefact, a dog whip mounted on the sled. This study highlights that the bone sled reflects a historic period of the early nineteenth century, during which the Inughuit were isolated. We conclude that the dogsled technocomplex (an integrated system of technological components and processes) both demonstrates the opportunistic ingenuity of the Inughuit and has shaped important aspects of the society through time.
Reshaping Research Paradigms: Insights from a Large-Scale Project Based in Nunatsiavut, Labrador, Canada
Authors: Seidler Dylan , Saunders Michelle K. , Pamak Carla , Zurba Melanie , McCarney Paul , Bailey Megan , Bodwitch Hekia
Published: February 2025

Across Inuit Nunangat (the Inuit homelands of Canada) researchers have been called to engage ethically and meaningfully with community members to develop projects that support local goals. This article focuses on understanding such engagement in the context of Nunatsiavut, an Inuit-governed territory in the province of Newfoundland and Labrador, Canada. In 2022 we conducted 27 interviews with researchers (both southern- and community-based), Inuit government representatives, and NGO representatives associated with the transdisciplinary SakKijânginnaKullugit Nunatsiavut Sivunitsangit (Sustainable Nunatsiavut Futures [SNF]) Project. SakKijânginnaKullugit Nunatsiavut Sivunitsangit began in 2020 and was designed, in part, to facilitate the co-production of knowledge between researchers and community members about climatic changes in Nunatsiavut. Through interviews, we explored what ethical and meaningful community engagement means in the context of a large-scale transdisciplinary project. Drawing on an analysis of interview data, we examine how project members and partners engage with Inuit community members, and how members of the project team who are Inuit have experienced these engagements. Based on participant responses, we identified elements needed for, and barriers to, ethical and meaningful engagement. We also heard about possible solutions. University researchers described institutional constraints to long-term engagement, while members of the Nunatsiavut Government staff and Inuit research coordinators emphasized that extractive (one-sided) forms of engagement can negatively impact communities. Interviewees described how a) restructuring academic and funding institutions, b) broadening engagement methods, and c) scaling down within a project can minimize the likelihood of negative effects and lead to more ethical and meaningful community engagement.
A Ortodontia de plástico e a sustentabilidade
Authors: Almeida Marcio
Published: February 2025

Não é novidade para ninguém que os alinhadores ortodônticos são considerados uma alternativa viável e substancial aos tradicionais aparelhos fixos. Na última década, a demanda pelos alinhadores aumentou demasiadamente, com o mercado global previsto para crescer de US$ 3,1 bilhões em 2021 para US$ 11,6 bilhões até 2027, representando uma taxa de crescimento anual composto de 13%, de acordo com Lee.
Tratamento da má oclusão de Classe II esquelética com mecânica ortodôntica e ortopédica: relato de caso
Authors: Bernardini Vanessa
Published: February 2025

﻿OBJETIVO: Relatar o caso clínico de uma paciente com má oclusão de Classe II esquelética e dentária. CASO CLÍNICO: Com base nos elementos diagnósticos e na avaliação clínica e facial, optou-se por um tratamento com abordagem ortopédica-ortodôntica. Iniciou-se o tratamento ortodôntico na fase interceptativa, com a montagem do aparelho extrabucal de tração cervical com força ortopédica (350g-400g/lado), obtendo-se controle do crescimento da maxila e um ajuste do plano anteroposterior das bases ósseas. Na fase corretiva, foi colado o aparelho ortodôntico fixo e realizou-se...
Playing with funds of difficult knowledge: interactional insights for heritage language education
Authors: Becker Ava
Published: February 2025

Migration stories are at the heart of how many immigrant-background Heritage Language Learners (HLLs) construct a sense of home, community, and identity across spatiotemporal scales. Nevertheless, narratives containing difficult knowledge (e.g., about war) are generally seen as threats to, rather than as assets in language learning and in education more broadly, and as such, are rarely drawn on in classrooms. In this paper I analyse excerpts from a group interview that I conducted with four grade-four girls during a year-long ethnographic case study. In particular, I examine how we all used various linguistic and paralingiustic resources to construct play frames. The play frames created a lower-stakes space in which to navigate the emotionally complex cultural memories that my interview questions about origins and migration prompted. The findings have implications for how language teachers listen to and engage with their HLLs’ funds of difficult knowledge.
Migration, subjectivity and identity: navigating power, agency and discourse in interviews with asylum seekers
Authors: Mazzaferro Gerardo
Published: February 2025

Drawing on Judith Butler’s theory of performativity and positioning approaches, this paper examines how asylum seekers actively assert agency in navigating and (re)constructing their subjectivities and identities within research interviews. The analysis explores the power dynamics inherent in the interview setting and broader public discourse, revealing how asylum seekers engage with and respond to these forces. Rather than being passive subjects of discourse, they employ performative-positioning acts to negotiate power structures and assert control over their self-representations. By analyzing interview data, this study highlights the dynamic interplay between power, discourse and agency in the ongoing construction of identity.
Tool evolution as a prerequisite for consciousness
Authors: Korth Carsten
Published: February 2025

Within the concept of the extended mind, the active modification of external objects, externalizations, is seen as an auxiliary means to adapt to the environment. Toolmaking and use are advanced stages of externalizations that evolve. All past or present tools can, theoretically, be precisely assigned a location in an evolutionary tree with predecessors and progeny. Tools are reliably replicated, modified, and selected by their ability to facilitate human needs. Tool evolution, therefore, fulfills Darwinian criteria where the material tool is the phenotype and the instruction to build it is the code. The ostensive triangle consisting of a pointing individual, an observing individual, and a pointed-at object or tool is the germ cell of social transmission of instructions. Tool-building instructions ultimately can be reduced to distinct sequences of motor acts that can be recombined and are socially transmitted. When executed, they replicate tools for the reward of convenience or improved fitness. Tools elicit affordances relating to their use that synchronize different individuals’ perceptions, result in psychological “understanding,” and thereby modify social networks. Massive tool fabrication as present today in the “tool-sphere” has, therefore, accelerated prosociality and over time led to the acquisition of an individual’s third person perspective. The entangled biological evolution accelerated the ongoing cumulative cultural evolution by selecting traits facilitating social transmission. In this context, tool evolution and the corresponding acquired individual instructional content is a precondition to the emergence of higher cognition and “consciousness.” A neuroscience investigating externalizations as the starting point of this process is urgently needed.
Accuracy validation and user performance analysis of two new self-monitoring blood glucose systems
Authors: Huang Tun-Yu , Chen Yu-Hsi , Li Yu-Ching , Chiu Yen-Hsin , Kang Hui-Jun , Chen Chih-Yu
Published: February 2025

Patients with diabetes require regular blood glucose monitoring. We evaluated the precision and user performance of two blood glucose monitoring systems, the accuracy results of GlucoTeq BGM200 and DiaRite BGM300, adhering to the EN_ISO 15197:2015 standards, which require blood glucose ≥100 mg/dL, >95% of the data within ±15% difference, and when blood glucose <100 mg/dL, >95% of the data within ±15 mg/dL. This study assessed their conformity with the YSI analyzer and other leading systems. Participants (n = 101), 18 years of age were included, covering a diverse demographic. Accuracy was determined using the YSI analyzer as the standard, employing linear regression, a consensus error grid and Bland–Altman analyses. The performance of both system users showed 100% conformity within zone A of the consensus error grid, high linear regression coefficients and minimal bias in the Bland–Altman analysis. Subjective satisfaction analyses showed average scores of 4.59 and 4.62 for BGM200 and BGM300, respectively. Comparison with other systems revealed high regression coefficients (CONTOUR®PLUS; R
2 = 0.9960, BGM200; R
2 = 0.9927, BGM300; R
2 = 0.9915, Accu-Chek® Guide; R
2 = 0.9910). Both systems demonstrated reasonable accuracy and user performance comparable to competitors’ products and met international standards. Their reliability in real-world scenarios and high user satisfaction make them valuable tools for diabetes management.

Learning points

Reasonable accuracy: GlucoTeq BGM200 and DiaRite BGM300 complied with EN ISO 15197:2015 standards, achieving >95% accuracy validated against the reference method the YSI analyzer.

High user satisfaction: both systems scored highly (4.59–4.62/5), reflecting ease of use, reliable operation and clear result interpretation.

Competitive performance: comparable to leading devices such as CONTOUR®PLUS, with strong correlation coefficients (>0.99).

Regulatory compliance: the trial met stringent international standards with a diverse participant group and robust methodology.

Broad applicability: reliable for clinical and home use, supporting effective diabetes management.
Corporate Social Responsibility Research in Green Catering Industry: Service-profit Chain
Authors:   National Kaohsiung University of Science and Technology, Ting Su Hsiang , Chen Wang Shu ,   Newealth Consoulting Ltd. and CEO of Jiami friendly restaurant
Published: February 2025

The purpose of this article is to propose corporate social responsibility (CSR) and to investigate CSR definitions published in green catering industry to the proposed service-profit chain (SPC) framework. Corporate ethics focuses on the decision-making and activities of individual employees, while corporate social responsibility is the ethical behavior at the corporate level. There is frequent interaction between enterprises and society, and the society often expects enterprises to give back the society and fulfill the responsibility of protecting and benefiting society. With economic development and Chinese people’s increasing demands on food culture, consumers also have more diversified food and beverage choices. Green food and beverages pay more attention to social responsibility when operating. In addition to paying attention to the competitive pressure of enterprises, they also integrate social factors, pay attention to environmental protection, resource conservation, respect for the interests and health of service quality of consumers’ meals. How to eat healthy and delicious, consumers have more diversified dining options to enhance customers’ value. Most of the customers’ impressions of catering are mainly from the service quality of catering ingredients, restaurant interior decoration and overall service level. Customers pay attention to the source of the food and the details of the service. The quality of the food is definitely a competitive advantage. High-quality meals and services also require good management. This research takes the Rice revolution vegetarian restaurant as a case study, and conducts an integrated analysis with the data of in-depth research. The friendly dining environment of green catering cooperates with small farmers, from the table to the place of production. This research provides high-quality meals and services to consumers’ dining guides, thereby enhancing their competitive advantages and performance.
La expulsión de la gitana vieja en La gitanilla de Miguel de Cervantes
Authors: Rouhi Leyla
Published: February 2025

Una característica ampliamente documentada de las obras de Miguel de Cervantes (1547-1616) es su problematización de las definiciones de identidades marginales. Pero una figura marginal que merece más consideración es la vieja gitana, la «abuela» de Preciosa en La gitanilla, cuya proyección corresponde a todos los marcos estereotípicos de su edad y oficio. El estigma de la vejez femenina, junto con la despreciada identidad de gitana, facilitan conclusiones categóricas acerca de su personaje, y el texto mismo permite una evaluación rotundamente ética de su comportamiento. Sin embargo, el entorno social retratado en la novela y la construcción lingüística del personaje crean posibilidades interpretativas que superan un mero juicio ético. El detallado análisis del personaje revela que la supuesta división entre la vitalidad de la joven Preciosa y la decrepitud de la gitana vieja no es tan clara como ha supuesto la gran mayoría de la crítica, y que en realidad existe una continuidad sombría que conecta a las dos.
La corona aúlica de la senectud: el gobierno de la vejez en los virreinatos americanos (ss. XVI-XIX)
Authors: Jiménez Castillo Juan
Published: February 2025

Este trabajo analiza la evolución política y moral de la senectud en el gobierno de los reinos de las Indias durante la Edad Moderna. El objetivo es reconocer cómo los procesos políticos e ideológicos que experimentó la Monarquía hispana afectaron al concepto y práctica de la vejez, así como cuán fue de relevante la asignación de los mayores magisterios regios americanos en personas longevas y si ésta fue determinante para su gobernabilidad. Por otro lado, se precisa hasta qué punto la vejez estaba arraiga a la majestad y si ésta fue definitiva para mantener a oficiales longevos en el poder.
Para los futuros estudios del gracioso alarconiano
Authors: Gómez Jesús
Published: February 2025

Es necesario establecer sobre la definición de gracioso un acuerdo básico, cuyo desarrollo podría ser útil para los futuros estudios sobre este subtipo cómico del criado, tan característico de la comedia nueva. Con respecto al modelo previo establecido por Lope de Vega, se analizan las variantes significativas que introduce Ruiz de Alarcón en la comicidad de sus graciosos más característicos, como Beltrán en Las paredes oyen y Tristán en La verdad sospechosa.
El maridaje entre latín y vernáculo en el quinientos: la impronta del ciblo hispano de «Renaldos de Montalbán» en la «Lyra Heroyca» (1581) de Francisco Núñez de Oria
Authors: Fernández Ríos María
Published: February 2025

Para el presente trabajo rescatamos el poema neolatino Lyra Heroyca (Salamanca, Matías Gast, 1581), tan poco conocido como su autor, Francisco Núñez de Oria. En esta extensa epopeya, el humanista reescribe en latín el Orlando Furioso de Ludovico Ariosto en clave patriótica, ajustándose al esquema del hexámetro dactílico. Si bien esta es su fuente vernácula principal, nuestro propósito con este trabajo es demostrar que Núñez de Oria también bebe, para componer estos versos latinos, de la materia que le brinda el ciclo caballeresco hispano de Renaldos de Montalbán.
De nuevo con «La carta de las calidades de un casamiento» de Francisco de Quevedo
Authors: Ferreira Barrocal Jorge
Published: February 2025

En este ensayo revisamos un pasaje de La carta de las calidades de un casamiento de Quevedo que presenta problemas textuales. Por un lado, tenemos las variantes de la versión de la carta aparecida en el MSS/20274/3 de la BNE, que Hermes (2014) utiliza como texto base de su edición. Por otro lado, tenemos las variantes de la edición príncipe. En la primera parte del artículo se ofrecen al lector unas notas sobre la tradición crítica de la Carta y el motivo de la dueña en Quevedo. En la segunda parte, analizamos las lecciones conflictivas de ambos testimonios, y, después, examinamos un fragmento inicial que falta en el códice. A la luz del escrutinio se concluye que la princeps trae las lecturas genuinas.
La voz del profesorado español en tiempos de pandemia. Un coro a siete voces.
Authors: Sánchez Hernández Ignacio , Pérez Rubio Karen , Verástegui Martínez Macarena
Published: February 2025

La emergencia sociosanitaria originada por la pandemia de Covid-19 situó al profesorado ante un insólito y desafiante escenario, especialmente durante el último trimestre del curso escolar 2019/20, en el que la enseñanza pasó a desarrollarse íntegramente en un entorno online. Sin embargo, son pocos los recursos que se han dedicado a escuchar atentamente lo que el profesorado tiene que decir sobre la situación vivida. Utilizando el método de estudio de casos, el presente artículo recoge las voces y las experiencias de siete docentes con el objetivo de examinar sus necesidades, anhelos y percepciones respecto a su rol, sentido y propósito profesional, y respecto a los procesos y relaciones de pertenencia dentro del cuerpo profesional docente durante aquellos meses. Para ello, se ha utilizado una entrevista en profundidad y un cuestionario, pasado en dos ocasiones, que se han sometido al método de análisis del discurso dentro del marco de una investigación cualitativa. Consideramos que las políticas públicas sobre el profesorado deben ubicar y repensar al docente como un sujeto generador de un conocimiento imprescindible para la comprensión del sistema educativo y, en ese sentido, lo que estas voces singulares nos descubren ha de ser tenido en cuenta a la hora de desarrollar mejoras educativas contextuales y efectivas.
¿Puede la educación virtual en la universidad ser mejor o igual valorada por los alumnos que la presencial? El caso de CEIPA Business School (Colombia)
Authors: Tahull Fort Joan , Boada Antonio , Cardona Montoya Giovanny
Published: February 2025

El estudio presenta una descripción, análisis y reflexión sobre las posibilidades y fortalezas de la educación virtual y se compara con la presencial. Se presenta el caso de la Institución Universitaria CEIPA Business School durante la pandemia del Covid-19. Para la investigación se ha utilizado bibliografía relevante y datos cuantitativos; principalmente las valoraciones de los alumnos egresados de CEIPA en diferentes periodos (prepandemia y pandemia); también se comparan los resultados educativos de las competencias específicas de CEIPA en sus diferentes modalidades con el promedio nacional en diferentes años. Los estudiantes de CEIPA reconocen la excelencia de la educación recibida en la modalidad presencial y virtual. En numerosos periodos, la educación telemática tiene mejor valoración que la presencial; además, según las Pruebas Saber Pro, las titulaciones de CEIPA de la modalidad virtual tienen en todos los años resultados muy superiores al promedio de las universidades colombianas.
Revisión sistemática sobre valoraciones de las habilidades docentes en el aula universitaria
Authors: Yáñez Galleguillos Luz María
Published: February 2025

Durante el último tiempo, las universidades han manifestado una alta preocupación por cómo enseñan los profesionales en la universidad, debido a que en la forma como enseñan dichos profesionales en las instituciones de educación superior, tendrá una repercusión directa en los aprendizajes de los estudiantes. Desde allí surge el objetivo de la presente revisión, referido a analizar las valoraciones sobre las habilidades docentes del aula universitaria. El presente estudio hace una revisión sistemática, bajo el método PRISMA, que incluyó 21 artículos científicos sobre la materia. Los títulos revisados obraron desde el año 2016 hasta el año 2022, buscados en bases de datos Scopus y Scielo. Los resultados apuntan hacia la importancia de las habilidades del aspecto personal, en tanto, disposición del profesorado a establecer relaciones e interacciones humanas en el aula, por sobre los aspectos formales y técnicos de quien enseña. Los aspectos personales  de los docentes son los más valorados y en este sentido la ética y su poder transformador en la actuación docente, como también la importancia del impacto de su intervención en otro y su convicción por enseñar o sobre valores esenciales para la docencia, requieren ser observados por las instituciones quienes están más centradas en preparar programas dirigidos a la impartición de técnicas a modo de recetario, más que en desarrollar en el/la docente la valoración por el acto educativo.
Properties of plastic composites filled with giant reed flour and magnesium oxide nanoparticles
Authors: Ayrilmis Nadir , Yurttas Elif , Avsar Esra Yildiz , Kahraman Memet Vezir , Özdemir Ferhat , Palanisamy Sivasubramanian , Yetiş Ferhat , Gurusamy Madhan Kumar , Al-Farraj Saleh A
Published: February 2025

Wood plastic composites (WPCs) were produced from recycled polypropylene (RPP) matrix, giant reed (GR) flour, and magnesium oxide nanoparticles (nano-MgO). The physical, mechanical, and thermal properties were analyzed. Different amounts of GR flour from 10 wt% to 40 wt%, and nano-MgO from 1.0 wt% to 2 wt% were added into the RPP matrix. The water resistance, mechanical, and thermal properties of the injection molded WPCs were determined according to the ISO standards. The bending and tensile modulus of the WPCs were considerably enhanced with the addition of the GR flour up to 40 wt%, while this was found to be maximum at 30 wt% for the bending and tensile strengths. The water absorption of the WPCs increased with the addition of the GR flour, as expected. The results of thermal analysis revealed that the addition of the GR flour increased the thermal stability of the WPCs, especially the degree of crystallization and the melting enthalpies of the RPP matrix, due to the good adhesion between the GR flour and the RPP. The incorporation of the nano-MgO affected adversely the mechanical properties of the WPCs. Lower thermal stability was observed for WPCs containing nano-MgO. The inclusion of 30 wt% GR flour in the RPP matrix gave the best mechanical and thermal properties.
Valorization of agricultural residues: Challenges and opportunities in the production of bio-based materials
Authors: Liu Jun , Wang Xiangyu , Fan Zhixiong , Liu Zhiren , Xu Ping , Sawant Trupti Rohan , Huang Guijuan , Deng Xinxin , Guo Jiaqi , Wang Jin , Zhou Mengbo
Published: February 2025

Environmental pollution and resource waste resulting from the disposal of agricultural biomass waste have become a global issue. Consequently, the pursuit of sustainable strategies for recycling such waste biomass and achieving its efficient and high-value conversion has emerged as a critical challenge that presents for both the global academic and industrial communities. This work provides a comprehensive overview of the current advancements in recycling and conversion of agricultural biomass waste into a variety of bio-based materials, with a particular focus on the biochar, nanocellulose, and bio-based plastics. Potential applications of these bio-based materials in agriculture and beyond with high added-value, such as cosmetics and biomedicine, are discussed with representative cases study. This review also highlights the challenges and future prospects in converting agricultural residues into various bio-based materials. It is hoped that this review will contribute to the understanding and promotion of recycling and reutilization of agricultural biomass waste, offering promising solutions for sustainable development of agricultural production.
Unraveling the Potential of Micro-nano Bubbles in Water Treatment: A Review Focusing on Physicochemical Properties, Generation Methods, and Environmental Impacts
Authors: Li Ling , Liu Honglin , Huang Yingping , Hong Feng , Yuan Xi , Cai Wei , Chen Chuncheng , Huang Di
Published: February 2025

With the advancement of industrialization, water pollution has become a pressing global environmental issue. Traditional water treatment technologies are struggling to remove emerging contaminants and meet current discharge standards, against this backdrop, micro-nano bubbles (MNBs) technology has attracted considerable research attention due to its unique physicochemical properties, such as long-term stability, high internal pressure, photoelectric characteristics, and reactive oxygen species (ROS) generation capabilities, especially in its combination with advanced oxidation processes (AOPs). A comprehensive understanding of MNBs generation and utilization is significant for developing green, economical, and highly effective wastewater treatment technologies. Herein, on the basis of the comprehensive literature survey, this review article systematically studied the distinctive characteristics of MNBs, along with the methodologies employed for their generation. It concurrently explores the characterization methods used to assess the properties of MNBs, which is instrumental for subsequent analyses on how these properties can enhance the catalytic performance of AOPs. Finally, this article explores the potential applications of MNBs in the environmental sector and points out the direction for future research, including the development of more efficient and cost-effective MNBs generation technologies, in-depth exploration of their mechanisms in AOPs, and comprehensive environmental impact assessments. This review aims to provide readers with an in-depth understanding of the intrinsic correlation between the properties and applications of MNBs, thereby enabling their optimal utilization in the environmental remediation.
Patient - prosthesis mismatch and its influence on immediate postoperative Von Willebrand factor levels in aortic valve replacement surgery
Authors: Grigorescu Andrei Emanuel , Anghel Andrei , Matichescu Anamaria , Feier Horea
Published: February 2025

Background and aims. Aortic stenosis (AS) often requires surgical aortic valve replacement (SAVR). Patient-prosthesis mismatch (PPM) can lead to suboptimal outcomes. Von Willebrand factor (VWF), crucial for hemostasis, is altered in AS patients. As part of an ongoing study, this research focuses on the impact of PPM on immediate postprocedural VWF levels in SAVR patients, building upon our previous publication on short-term VWF dynamics in SAVR and TAVR.
Methods. This prospective study included 31 consecutive patients with severe AS undergoing SAVR. Preoperative and postoperative VWF levels were measured. PPM was assessed based on the indexed effective orifice area of the implanted valve.
Results. PPM was observed in 61.29% of patients. Postoperative VWF antigen levels increased significantly (131.37 ± 64.82 IU/dL to 311.01 IU/dL, p<0.01). However, PPM did not significantly influence postoperative VWF antigen levels (285.43 IU/dL vs. 293.30 IU/dL, p=0.88), VWF activity (178.33% vs. 204.76%, p=0.56), or Factor VIII levels (100.38 IU/dL vs. 97.10 IU/dL, p=0.79).
Conclusions. While SAVR led to increased VWF levels, PPM did not impact short-term VWF dynamics. This study provides insights into PPM and VWF relationships in SAVR patients, informing valve selection and perioperative management strategies. A future paper will reveal long-term follow-up results, completing this comprehensive investigation of VWF dynamics in aortic valve interventions.
Childhood Opportunity Index and Outcomes Across the Care Continuum for Children With Asthma
Authors: Byrne Alexandra , Hall Matt , Berry Jay , Parikh Kavita , Tyris Jordan , Reyes Mario , Perdomo Joanna
Published: February 2025

BACKGROUND

The Childhood Opportunity Index (COI) is a multidimensional measure of neighborhood features associated with child health. Our objective was to determine if COI is associated with outcomes across the care continuum in children hospitalized for asthma.

METHODS

This is a retrospective cohort study using the Pediatric Health Information System database of hospitalized children with asthma aged 2 to 18 years from May 1 2021 to April 30, 2022. Main exposure was COI. Outcomes were categorized into 3 periods: prehospitalization (illness severity), during hospitalization (length of stay [LOS] and cost), and posthospitalization (emergency department [ED] revisits and rehospitalizations within 365 days). Multivariable relationships between COI and outcomes were assessed with generalized estimating equations, adjusting for illness severity and age, sex, and clustering data by hospital.

RESULTS

Of 19 119 asthma hospitalizations, 37.6% were for children with very low COI. Children with very low and low COI more often had critical or severe illness compared with children with high and very high COI (56.4% vs 47.5%, P < .001). COI was not associated with adjusted LOS (P = .1) or cost (P = .1). Children with very low vs very high COI were more likely to revisit the ED (odds ratio [OR], 2.2; 95% CI, 1.8–2.5) and be rehospitalized (OR, 1.8; 95% CI, 1.6–2.1) within 365 days.

CONCLUSION

Children with lower COI hospitalized for asthma were more often critically ill and experienced more ED revisits and rehospitalizations than children with higher COI but had similar adjusted LOS and cost. Evaluating outcomes across the care continuum, including before, during, and during hospitalization, rather than a single point in time may help identify disparities and develop targeted interventions.
Factors Associated With Delay to Care in Pediatric and Adolescent Adnexal Torsion
Authors: Rich Barrie S. , Roberts Bailey , Nofi Colleen , Glick Richard D. , Fisher Jason C. , Durkin Emily , Ignacio Romeo , Garcia Carlos , Alexander Abigail , Short Scott , Krinock Derek , Wolf Lindsey L. , Weiss Richard , Ryan Emma , Robertson Daniel J. , Abebrese Emmanuel , Van Arendonk Kyle J. , Hwang Rosa , Nace Gary , Cerise Jane , Rothstein David H.
Published: February 2025

BACKGROUND AND OBJECTIVES

Diagnosis of adnexal torsion is challenging due to variable clinical presentations and often inconclusive imaging results. We hypothesized that diagnostic delays are common, leading to prolonged ischemia and subsequent tissue loss. We aimed to identify factors associated with diagnostic delays in pediatric patients with adnexal torsion.

METHODS

We performed a multi-institutional retrospective review of females aged 5 to 18 years with confirmed adnexal torsion between 2013 to 2022. Delay to care was defined as prior emergency department discharge within 7 days of operation and/or hospital admission without initial plan for operation.

RESULTS

862 patients were identified from 10 children’s hospitals, with delayed diagnosis in 30%. Patients with delay were less likely to present with emesis or fever, have initial pediatric surgery consultation, or have typical ultrasound findings of torsion compared to those without delay (P < .05). For every unit increase in area deprivation index, the odds of delay increased by 1.3% (odds ratio 1.013, 95% CI, 1.007–1.018). The odds of delay were 81% greater for patients living > 30 miles from the hospital compared with 1–10 miles (odds ratio 1.812, 95% CI, 1.236–2.657). Oophorectomy and salpingectomy rates were 10% and 13%; those with delay had higher risk of oophorectomy (14% vs 7%, P = .002).

CONCLUSION

Delayed diagnosis of adnexal torsion is common and associated with higher area deprivation index and farther distance from hospital. Risk of oophorectomy was higher in patients with delay. Improved diagnostics and increased awareness of social disparities are critical to decrease time to definitive treatment and improve rates of adnexal salvage.
Echa idei golema w powieści Inne pieśni Jacka Dukaja
Authors: Benešová Michala
Published: February 2025

The text aims to analyse the way in which the Polish novelist Jacek Dukaj’s novel Inne pieśni [Other Songs] reflects echoes of the originally Jewish concept of the golem, an artificial creature animated by man. It first briefly summarises various interpretations of the golem idea and briefly characterises the novel under analysis, before comparing selected motifs from the novel with the characteristic attributes of the golem (its specific ontological status, its imperfection, its resemblance to man, etc.). Finally, the text briefly mentions other golem motifs appearing in Jacek Dukaj’s work.
Humorystyczna twórczość gwarowa w literaturze Śląska Cieszyńskiego
Authors: Przywara Michal
Published: February 2025

The purpose of this article is to present the characteristic features of dialectal humor in literature of Cieszyn Silesia. The analysis is based on the basic division of comedy: situation, verbal and characters. All three types are noticeable in Cieszyn literature, but situational comedy and verbal comedy are the most common, especially in short, condensed forms such as the anecdote or the joke, which are among the best-loved humour genres and have a long-standing tradition in Cieszyn. The results are related to the author’s work: Karol Piegza, Karol Daniel Kadłubiec, Adam Wawrosz, Aniela Kupiec and Henryk Jasiczek.
The Verbal Representation of the Category of «Honor» by Means of the Ukrainian Phraseology in Media Discourse
Authors: Kniaz Tetiana
Published: February 2025

The processes of language reflection of the category of «honor» by means of the Ukrainian phraseology in the minds of Ukrainians are analyzed, as well as functional and pragmatic, structural and semantic features of phraseological units (PhUs) in media discourse are found out. At the phraseological level, the informational content of the category of «honor» is formed by the following cognitive features: honor is an expression of pride, showing respect, respect for someone or something; honor is a virtue; it is reputation; honor is honesty, etc. The analyzed usual and transformed PhUs reflecting the moral and ethical characteristics of the individual in the media discourse characterize the deep national and cultural mechanisms in the context of various discursive practices. Functional and pragmatic efficiency of using of PhUs in media discourse is explained by desire of communicators to realize maximally exactly a number of communicative functions: message, informing the influence on consciousness, emotional influence, the function of achieving empathy, etc.
Forming Phonetic Memory in the Cognitive Process of Children and Adults – Reflections from Research
Authors: Borowska Barbara
Published: February 2025

Memory processes play a special role in the cognitive development of both children and adults. In the course of personal activity, more and more new objects and phenomena become familiar. Sensory, visual, auditory and kinesthetic sensitivity then expands. In relation to reading, visual and auditory memory makes it possible to reproduce acquired graphic signs, to perceive the distinctive features of letters and sounds. The information stored in memory enables the reader to access the knowledge he or she possesses, thus ensuring the continuity of information processing (Jagodzińska, 2003). Research exploring direct memory among adults was conducted by, among others, George A. Miller (1956). He found that, irrespective of the type of material being remembered, the range of direct memory is between 5 and 9 elements, or 7±2 elements. An element can be any memorised content, e.g. a digit, a phoneme, a word or a sequence of digits, phonemes or words. This range has been called the ‚Miller magic number‘. On the other hand, Edyta Gruszczyk-Kolczyńska (2005) stated that children‘s memory is dominated by involuntary memory and is closely linked to action. She also accentuated that the majority of research on memorisation is conducted among adults. With regard to children, the mechanisms of retrieval from memory are rarely explored. Following the above and the research findings of G. A. Miller (1956) and Alan Baddeley (1992), I decided to investigate phonetic memory among pre-school children. The study took place in 2018 with a sample of 260 six-year-olds and was conducted in two stages (January, June).
Changing Resources in Transylvanian Villages from Self-Sufficient Households to the Global Market
Authors: Szabó Árpád Töhötöm
Published: February 2025

One important component of our accumulated knowledge about Transylvanian villages is the (partial) autonomy of these villages, understood from a historical perspective, at the level of both households and village communities. Another important component is the marked presence of interhousehold cooperation. Based on this autonomy and cooperation, and their eradication, the present paper argues that social, economic, and political restructuring has made village communities, once heavily reliant on endogenous resources, increasingly dependent on external, exogenous resources. Drawing on research in Transylvanian contexts, mainly in Bahnea/Bonyha and Nuşfalău/Szilágynagyfalu, the paper explores the process of eradication, and its contradictions, by discussing changes in animal husbandry, household management, foraging, and time spent in nature, before placing it in a global context using historical and recent examples. The paper then addresses the question of how all these aspects can be understood in terms of resilience, sustainability, and complexity.
The First Russian Experience of Using Palovarotene for the Treatment of Fibrodysplasia Ossificans Progressiva: Two Case Reports
Authors: Nikishina Irina P. , Matkava Valeriya G. , Arsenyeva Svetlana V. , Gasymov Emil G. , Arefieva Alia N.
Published: February 2025

Background. Fibrodysplasia ossificans progressiva (FOP) — is an extremely rare genetic disorder with an autosomal dominant type of inheritance. FOP is associated with a genetically determined disorder caused by the presence of a specific mutation in the ACVR1/ALK2 gene encoding the bone morphogenetic protein receptor. FOP is clinically manifested by the unrestrained formation of heterotopic ossifications, leading to a gradual progression of disability up to complete immobility of the patient. At an early age, the disease can be recognized by the presence of characteristic phenotypic stigmas, mainly the characteristic malformation of the thumbs, confirming the diagnosis by molecular genetic analysis. Early diagnosis of FOP avoids unnecessary iatrogenic manipulations and slows down the progression of the disease. Up until recently, there was no therapy that had a pathogenetic effect, preventing the development of ossifications. The first and only drug that has proven its effectiveness as a result of clinical trials and is registered for use in patients with FOP in a number of countries is palovarotene.

Case reports: The publication presents the first Russian experience of using palovarotene with a description of two clinical observations of patients with a genetically confirmed diagnosis of FOP. The clinical picture, the difficult path to diagnosis, and the encouraging experience of treating patients, including anti-inflammatory therapy using Janus kinase inhibitors (tofacitinib) and pathogenetic therapy with palovarotene, are described.

Conclusion. The aggressive nature of the course of FOP, which inevitably leads to severe disability of patients, necessitates the widespread attention of practitioners to the early diagnosis of FOP, an in-depth study of the factors determining progression, and new opportunities for pathogenetic therapy allow us to count on improving the prognosis of this extremely serious disease.
Magnum miraculum: os fundamentos da dignidade humana na filosofia oculta renascentista
Authors: Noronha de Andrade Thainan
Published: February 2025

A dignidade humana foi um dos elementos centrais da cultura do Renascimento, produzindo consequências decisivas em diversos campos epistemológicos no decorrer dos séculos XIV e XVI e mudando, direta ou indiretamente, o curso da filosofia ocidental nos próximos séculos. O presente artigo aborda a consolidação desta visão, enfatizando como ela acompanhou os desenvolvimentos intelectuais do período renascentista, em especial, aquele marcado pelo interesse renovado pelo platonismo e outras correntes de inspiração mística e esotérica, fenômeno que teve em Florença seu principal centro propulsor. Como resultado da popularidade destas correntes de orientação platonizante, o presente trabalho mostra como isso se refletiu sobre as diversas visões sobre o ser humano. Inicialmente louvado por humanistas por sua virtude e razão, o individuo converte-se em verdadeiro herdeiro e expressão terrena do divino.
Do romanesco grego por Nicetas Eugeniano: considerações; tradução; notas; bibliografia
Authors: Troca Pereira Reina Marisol
Published: February 2025

Da autoria de Nicetas Eugeniano, um dos quatro romances bizantinos que sobreviveu ao tempo, surge uma obra que retoma temas da Antiguidade Clássica. Este texto literário, realizado no duodécimo século, durante o período comneno, integra elementos da esfera cultural bizantina sob a influência de um paradigma judaico-cristão. A história em apreço é a 'fabula amatoria' que relata as peripécias amorosas de Drosila e Cáricles. Apesar de ser considerada uma imitação de segunda ordem, carente de originalidade em personagens, estilo, linguagem e ritmo, esta monodia versificada em nove livros quebra a passividade ao introduzir dialogismo intertextual, alusões, citações e a participação de um elenco evocado em discurso indireto livre. Observa-se na diegese uma conjugação multifacetada de vetores, com exemplos de lutas, paixões, sofrimentos, descrições, mortes, lamentos, ciúmes, memórias, hospitalidade e enganos. Apesar de ter registado uma divulgação limitada, apresentando várias variações e lacunas, esta ficção é um valioso reflexo da vitalidade do passado, evidenciando a capacidade de integração e reconstrução, mantendo relevância na sua atualidade medieval. Provavelmente composta como um tributo a Teodoro Pródromo, a obra destaca-se pela sua contribuição singular.