bluuebunny/crossref_metadata_2025 huggingface dataset:
ADVERSE EVENTS FOLLOWING ChAdOx1 nCoV-19 (COVISHIELD) VACCINE IN KASHMIR VALLEY: FINDINGS FROM FOLLOW-UP OF VACCINE RECIPIENTS USING ACTIVE SURVEILLANCE.
Authors: Jeelani Asif , Majeed Mudasir , Aleem Seema , Khan S.M Salim , Raja Waseem
Published: September 2021

Introduction: Surveillance for adverse events after the rollout of a new vaccine is of paramount importance. This study was conducted to estimate
the frequency and characteristics Of Adverse Events Following Immunization with ChAdOx1 nCoV-19 vaccine.
Methods: An observational follow-up study design was used for vaccine recipients in the rst quarter of 2021. Using non-randomized method,
alternate subjects coming for vaccination were included. Baseline sociodemographic and any immediate AEFIs were recorded at the vaccination
site followed by computer-assisted telephonic interviews on days 1,3,7 and 30. The same protocol was followed after second dose. Sample size was
calculated using formula for prevalence studies. Standard case denitions were used for AEFIs. Chi-square test was used to test for signicance and
P-value of less than 0.05 was considered signicant
Results: th th A total of 652 subjects with a mean age of 59.1 ± 9.2 years were included. 3/4 of subjects were males and 1/4 were healthcare workers.
The most common systemic side effects after rst dose were fever (49.4%), Fatigue (43.6%) headache (38.6%), and chills/shivering (28.4%).
Myalgia/arthralgia developed in around 10% and diarrhea in around 3% of subjects. Among local symptoms, tenderness at the injection site, pain at
th the site were reported by almost half whereas warmth and swelling were reported by 1/5 of participants. Second dose had a similar AEFI prole.
h/o COVID-19 and younger age had a signicant association with incidence of AEFI.
Conclusion:Although around half of subjects developed any AEFI, most of these were minor and self-limiting.
PREVALENCE OF DIABETES AND HYPERTENSION IN THE YOUNG ADULT POPULATION.
Authors: Kundu B.K. , Kumar Deepak , Kaur Kirandeep
Published: September 2021

Aims and Objectives: To estimate the prevalence of Diabetes Mellitus and Hypertension in the young adults of age 18-39 years, who have
undergone pre-employment screening at a tertiary care hospital and document their parameters.
Materials and methods: Records of all candidates of either gender belonging to the age group 18 completed years to 39 completed years, who had
st th undergone pre-employment screening during the period of 1 January 2016 till 30 June 2020, preserved in the Department of Medical
Examination were examined for the purpose of this study. The candidates who had been diagnosed as hypertensive or diabetic or both were
tabulated. The results and values were tabulated in MS Excel. The statistical software JASPwas used for calculations.
Results: Records of 12257 candidates were scrutinized, out of which 9176 were males and 3081 were females. Atotal of 182 candidates were found
to be Diabetic, Hypertensive or both. Majority of the candidates were males (175 out of 182, 96.15%). The prevalence of Diabetes Mellitus was 179
and that of Hypertension was 1362 per 100,000 population.
Conclusion: Diabetes and/or Hypertension are not uncommon in the young population of 18 to 39 years of age. Most of them are males. End organ
affection can start early. Proper screening programmes can identify these cases early and ensure timely intervention.
PHENOTYPIC EXPRESSION OF MESENCHYMAL STEM CELLS: COMPARING SELECTIVE TISSUEENGINEERED PHOTOSTIMULATION TECHNIQUE AND CONVENTIONAL LIPOSUCTION TECHNIQUE.
Authors: Centurión Patricio , Aguirre Jorge Castillo , Pando TM Jhon , Yalán Antonio Carrasco , Talavera Jesus E.
Published: September 2021

Introduction: Adipose-derived stem cells (ASCs) show some membrane markers that enable cell identification by flow
cytometry. One of them which is essential during the angiogenesis process is CD105 (Endoglin). This is very important
for various pathologies where it is required angiogenesis to regenerate tissues or organs affected by various acquired or
congenital noxae. To determine the phenotypic expression, CD105 angiogenesis factor, of ASCs obtain Objective: ed by
Selective Tissue Engineering Photostimulation (STEP ) with infrared light of 1210 nm compared to those obtained by TM
Gold Standard Suction assisted lipectomy/conventional liposuction technique (SAL). ASCs obtained by Results: STEP™
technique with 1210 nm laser were found to be highly viable (> 97%) and showed increased CD105 expression (90%)
and only <5% with the SAL. ASC had been obtained after application of the STEP™ technique is highly Conclusion:
viable and show higher expression of specific marker CD105 than the ASC obtained by SAL.
LONG-TERM HEALTH OUTCOME AMONG HCV PATIENTS WITH ADVANCED LIVER FIBROSIS TREATED THROUGH HCV ELIMINATION PROGRAM IN GEORGIA
Authors: Mgeladze Mariam , Kamkamidze George
Published: September 2021

Goal: The main objective of our study was to evaluate the effect of long-term treatment in patients with high liver fibrosis
who have achieved a sustainable viral response (SVR) after receiving direct antiviral medication (DAA). Assess sociodemographic characteristics and clinical /laboratory data role in changing the level of liver fibrosis. The Methods:
study cohort included patients from the Hepatitis C Elimination Program treated with direct antiviral drugs (DAA), with
high-grade elastography-determined liver fibrosis (> = F3), and patients with a FIB4 score above 3.25 and sustainable
viral response is achieved within 12-24 weeks after completion of treatment. The study group was selected
retrospectively from Clinic Neolab's medical database and records. A total of 150 patients were studied. Data were
processed in the statistical program SPSS24. The Wilcoxon Signed Ranks test was used from the statistical tests.Results:
The study was conducted in 2020. These data were determined both before and after treatment. After treatment on the
metavir scale, liver damage levels improved in 51.7% of patients.Statistical analysis showed that the change in fibrosis
level after treatment was statistically significant (P <0.001). The study normalized data from laboratory studies such as Alt
(85,3%) and Ast (80 5%).
A NEW SPECIES OF PHYLLODISTOMUM (TREMATODA: GORGODERIDAE, LOOSS, 1899) FROM FRESHWATER FISH WALLAGO ATTU IN AKOLA DISTRICT (M.S.) INDIA
Authors: Khade Ravi , Thosar Amol , Tayade Sachin
Published: September 2021

The present investigation deals with the systematic observation of a new species of Phyllodistomum khadensis Sp. Nov.
from fresh water fish Wallago attu. The worm is close to all species of genus phyllodistomum in general the body is narrow
while the posterior portion of the body is broad and triangular in shape. The oral sucker is terminal. The ventral sucker is
rounded in structure and larger than oral sucker. The bladder is long and tubular.The anterior testis is smaller than
posterior one. Vas deferans is long, tubular and forms vasa efferentia. Female reproductive organ includes single ovary
having its duct. The vitelline glands are two in number compact lobes on either side of the ootype. The eggs are oval to
round in shape.
ENDOMETRIAL BIOPSIES PATTERNS AMONG WOMEN ATTENDING MOI TEACHING AND REFERRAL HOSPITAL, KENYA
Authors: Grace Andeso
Published: September 2021

Background: Endometrial diseases are among the most common gynecological disorders affecting women both
globally and locally;accounting for 60% of global maternal deaths.Kenya is ranked thirteenth out of 181 countries with
the highest maternal mortality globally. Endometrial disorders such as hyperplasia's, neoplastic, inflammatory and
pregnancy related conditions of the endometrium have been reported to increase with demographic traits such as
maternal age and parity.
Objective: To determine histopathological patterns of endometrial biopsies among women attending Moi Teaching
and Referral Hospital,Kenya.
Methods: This was a retrospective laboratory-based study where 121 banked endometrial biopsy blocks collected
from participants aged 19 to 70 years between August 2014 and August 2016 were retrieved, re-sectioned and stained
using routine histological (Hematoxylin and Eosin) stains in the histology laboratory before being sent to the pathologist
for examination. Sociodemographic and reproductive history data were collected from the medical records.
Descriptive statistical techniques such as cross-tabulation were used.The median age of all the study participants was 44
years.
Results: Most of the study participants (39.2%;n=38) presented with simple endometrial hyperplasia.The endometrial
patterns were categorized as Hyperplasias (50.4%; n=61), Inflammatory disorders (7.4%; n=9), Neoplastic Disorders
(14.9%;n=18),Pregnancy related disorders (20.7%;n=25) and other patterns (6.6%;n=8)
Conclusion: Majority of the study participants presented with simple endometrial hyperplasia followed by complex
hyperplasia and adenocarcinoma,respectively.
INJECTION SITE LIPODYSTROPHY WITH FAT NECROSIS: A RARE CASE REPORT
Authors: Kaur Navdeep , Dhar Reeta , Singh Arpita , Malhotra Vishakha
Published: September 2021

Lipodystrophies are dermatological complications due to repetitive subcutaneous injections leading to subsequent loss
of adipose tissue at the site of injection. Fat necrosis occursdue to concentrated pressure on microlobules of adipocytes
causing disruption of septa between these microlobules, leading to permanent changes in the injured site. In this report
we present a case of 63 year old female who developed lipodystrophy following subcutaneous injection in left lower
abdomen.
A STUDY ON THE DEMOGRAPHIC AND CLINICAL PROFILE OF WHEEZING IN THE FIRST YEAR OF LIFE
Authors: Das Sunita , Kumar Panda Deshish , Das Kedarnath , Behera Saiprasanna
Published: September 2021

This hospital based observational cross sectional study having a sample size of 100 was undertaken at S.C.B. Medical College and S.V.P.P.G.I.P.,Cuttack,with an objective to study the clinical profile and risk factors for wheezing in infancy from November 2018 to November 2020. Wheezing is accountable for a high demand of medical consultations and emergency care services with relatively high rates of hospitalization.In this study, several risk factors were identified for wheezing in less than one year of age which had little resemblance to similar studies made in various other age groups.However,maternal smoking as a risk factor could not be found in our study due to social cultural lifestyle in the study population. Factors like caesarean section, history of birth asphyxia, NICU admissions and living in kuccha house were not found to impose risk for wheezing in infancy in the study in contrary to similar such studies in other age groups.The present study revealed, that among all other etiology, the viral respiratory tract infections including bronchiolitis was the most common cause of wheezing in infancy (64%) followed by WALRI (wheeze associated lower respiratory tract infection). In conclusion, if an infant with wheezing has risk factors like male sex, preterm, more than six months age, family history of atopy or repeated upper respiratory tract illness or overcrowding in family, anticipating the severity recurrence should be suspected. These infants should be monitored closely for signs of clinical deterioration. Proper health education,ante natal and neonatal care,promoting of breast feeding and creating awareness to the public regarding modifiable risk factors like separation of family members having upper respiratory illness from young infants will reduce the severity of wheezing and will help prevent their recurrence to much extent.
A contribuição da laserterapia no processo de cicatrização das úlceras venosas nos membros inferiores
Authors: Andreia dos Santos Cinara , Plais Kátia , Ribeiro Christiana Vargas
Published: September 2021

Estudos têm mostrado que a laserterapia pode contribuir para a analgesia e a cicatrização de feridas, sendo um poderoso tratamento auxiliar em pacientes que apresentam úlceras venosas. Neste sentido, o presente trabalho tem como objetivo explanar a contribuição da laserterapia e a importância do trabalho multidisciplinar no tratamento de úlceras venosas através de uma revisão de literatura. As bases consultadas foram o Google Acadêmico, Scientific Electronic Library Online (SciELO), a Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e National Library of Medicine (PUBMED), nas quais foram pesquisados trabalhos realizados entre os anos de 1998 e 2015. Ao final deste estudo, concluiu-se que a equipe multidisciplinar é extremamente importante para o tratamento de úlceras venosas, pois existe a necessidade de cuidados tópicos e sistêmicos. Neste sentido, a laserterapia é uma aliada para o bem-estar dos pacientes. Entretanto, ainda são necessários mais estudos relacionados à aplicação do laser e seus benefícios no tratamento de pacientes portadores desta patologia.
ПЕРСПЕКТИВИ ЗАСТОСУВАННЯ ВОДНЕВИХ ТЕХНОЛОГІЙ ДЛЯ АВТОНОМНИХ ЕНЕРГЕТИЧНИХ КОМПЛЕКСІВ НА ОСНОВІ ВІДНОВЛЮВАНИХ ДЖЕРЕЛ ЕНЕРГІЇ
Authors: Чорна Н.А.
Published: September 2021

У статті проаналізовано публікації з використання водневих технологій, спрямованих на залучення відновлюваних джерел енергії в інфраструктуру енерготехнологічних комплексів, а саме для автономного енергозабезпечення невеликих споживачів на віддалених територіях. Потенціал використання сонячної та вітрової енергії в Україні є достатньо високим для широкого впровадження в енергетичні системи. При експлуатації автономних енергетичних комплексів на основі відновлюваних джерел енергії, таких як сонячна та вітрова енергія, можливе виникнення позаштатних ситуацій, обумовлених припиненням енергопостачання внаслідок мінливості енергонадходження або аварійним виходом з ладу окремих елементів енергокомплексу. Тому для забезпечення безперебійним електропостачанням автономного приватного споживача необхідно передбачати додаткові системи вирівнювання енергонадходження. Використання технології перетворення енергії від первинних джерел із застосуванням електролізної установки, металогідридної системи акумулювання водню та паливної комірки дасть змогу вирішити не тільки проблему згладжування нерівномірності надходження енергії від відновлюваних джерел енергії, а ще й зменшити екологічне навантаження на навколишнє середовище України. Проведений аналіз існуючих типів електролізерів показав, що водневі технології, які реалізуються в електролізних установках, розроблених в Інституті проблем машинобудування ім. А.М. Підгорного Національної академії наук України дозволяють виробляти і накопичувати водень під високим тиском (до 20 МПа), що виключає використання компресорної техніки. Застосування водню в паливних комірках дозволяє створювати ефективні системи автономного енергозабезпечення приватних споживачів. Найперспективнішими для автономних споживачів є енергоустановки потужністю від 1 до 20 кВт на основі низькотемпературних лужних паливних комірок, які характеризуються високим ККД, екологічною чистотою та безшумністю в роботі. Аналіз публікацій показав, що для забезпечення живленням паливних комірок найбільш компактним, безпечним та екологічним способом є використання металогідридних акумуляторів високочистого водню багаторазової дії в складі енергетичного комплексу, що відповідає вимогам розміщення автономних систем енергозабезпечення. Бібл. 31, табл. 3, рис. 5.
НАПРЯМИ ТА ПЕРСПЕКТИВИ РОЗВИТКУ СОНЯЧНОЇ ТЕПЛОЕНЕРГЕТИКИ
Authors: Матях С.В. , Суржик Т.В. , Рєзцов В.Ф. , Іванчук В.Ю.
Published: September 2021

У роботі представлено результати аналітичних досліджень щодо стану та перспектив розвитку сонячної теплової енергетики у світі та в Україні. Завдяки екологічним перевагам сонячних теплових технологій їх широке застосування є одним із перспективних напрямів декарбонізації світової енергетики. Розвитку сонячної теплоенергетики у світовій енергетиці приділяється серйозна увага і підтримка. Детальний огляд загальних світових тенденцій із документуванням сонячної теплової потужності, визначенням внеску сонячних теплових систем у постачання енергії та обсягів зменшення викидів вуглекислого газу за рахунок їх застосування показує постійно зростаючий попит на такі системи. У країнах з високим рівнем впровадження сонячного теплового обладнання створено повний комплекс нормативно-правового забезпечення даного процесу, на основі нормативно-методичного забезпечення і пакету засобів економічної підтримки діють ефективні державні програми.
Завдяки наявності значного енергетичного потенціалу сонячного випромінювання широке впровадження теплоенергетичного обладнання в Україні є ефективним практично на всій території. Сонячне теплове обладнання має широкий діапазон використання в різних галузях господарювання України, його встановлення не потребує спеціальних дозволів, що значно скорочує терміни впровадження. Теплові процеси, які використовують енергію сонячного випромінювання, досліджені та опрацьовані майже для всіх напрямів теплових технологій, на ринку сонячного енергетичного обладнання є широка гама необхідних пристроїв та обладнання, однак в Україні практично відсутні моніторинг та заходи стимулювання їх впровадження.
Для забезпечення масштабного впровадження сонячних теплових технологій в Україні необхідно створити комплекс нормативно-правового забезпечення даного процесу і розробити заходи щодо економічної підтримки як виробників енергетичного обладнання, так і споживачів теплової енергії. Відповідним державним органам необхідно підвищити рівень моніторингу даних щодо ефективності їх встановлення та експлуатації на території України. Важливим напрямом роботи є створення розгалуженої інфраструктури теплової сонячної енергетики з підрозділами на рівні місцевих територіальних громад. Бібл. 7, рис. 1.
Enfermedad tromboembólica y COVID-19: aparición, diagnóstico y tratamiento
Authors: Guzmán Moscoso Diana Laura
Published: September 2021

La enfermedad por Coronavirus 2019 (COVID-19) se produjo por el virus 2019 nCoV, aislado por primera vez en China a fines de diciembre de 2019, causante del Síndrome Respiratorio Agudo Severo 2 (SARS-CoV-2), mismo que en el transcurso de los últimos 18 meses asciende a 199 millones de contagios y más de 4 millones de muertes a nivel mundial, siendo las enfermedades trombóticas una de las principales causas de muerte asociadas. El tromboembolismo venoso es la principal causa prevenible de muerte en los hospitales en América Latina y en el mundo. Se estima que 1 de cada 4 muertes se relacionan con enfermedades tromboembólicas, aún sin el factor agravante del SARS-CoV-2.  Se buscó describir la enfermedad tromboembólica como una complicación de COVID-19, definiendo su aparición, diagnóstico oportuno y tratamiento de elección. Proceso que se llevó a cabo a través de una revisión exhaustiva de fuentes primarias y secundarias reconocidas a nivel internacional de dónde se pudo concluir que los eventos tromboembólicos son precedidos por un estado de hipercoagulabilidad desencadenado por la tormenta de citocinas propia de la viremia y activación patológica de la trombina que genera COVID-19. Los eventos tromboembólicos venosos resultan ser más incidentes que los eventos arteriales, con una mortalidad de 30-69% según el estadio de la enfermedad. La instauración del tratamiento debe ser de forma precoz desde el servicio de urgencias en todo paciente hospitalizado. La heparina de bajo peso molecular es actualmente el tratamiento de elección profiláctico y terapéutico en enfermedad tromboembólica por COVID-19.
Teoría de la pena
Authors: Ávila Aparicio Cesar Augusto
Published: September 2021

El trabajo desarrollado, se basa en realizar un análisis de los fines de la pena en base a las teorías que buscan establecer su justificación, se parte por explicar  el concepto de la misma, su naturaleza jurídica la cual tiene íntima relación con el principio de legalidad contenido en los artículos 17 de la Constitución Política de la República de Guatemala vigente, para explicar por último la actitud adoptada en la legislación guatemalteca. Dicho sistema jurídico cree en la rehabilitación  de los reclusos y en teoría el sistema penitenciario debería estar adecuado para ese fin, preparado e instalado con programas reales de rehabilitación, sostenibles, funcionales y reales, donde se pueda palpar un cambio de actitud y aptitud.
Peningkatan Kapasitas Petani pada Masa Pandemi COVID-19 Melalui Pelatihan Manajemen Keuangan & Pemasaran Digital
Authors: A. Pontoan Karen , A. Merung Yoseph , Kelana Gracia , R. Lengkong Meilany
Published: September 2021

Pandemi COVID-19 merupakan salah satu resiko yang dihadapi oleh sektor pertanian pada saat ini. Selain mengancam kesehatan petani, adanya kebijakan pembatasan pergerakan manusia untuk menekan penyebaran virus COVID-19 mengakibatkan terganggunya arus distribusi di sektor pertanian yang selanjutnya berdampak pada produktivitas dan pendapatan mereka. Kegiatan pengabdian kepada masyarakat yang bermitra dengan Kelompok Tani Gertak Milenial (KTGM) yang berada di Desa Keroit Kabupaten Minahasa Tenggara bertujuan untuk meningkatkan kapasitas petani dalam mengembangkan usaha pertanian di tengah ancaman pandemi. Melalui metode penyuluhan dan pelatihan yang dilakukan dalam kegiatan ini, para petani diajarkan bagaimana melakukan pengelolaan keuangan dan modal sosial serta bagaimana melakukan pemasaran digital. Pada akhir kegiatan ini dapat disimpulkan bahwa mitra dapat menyerap pengetahuan yang diberikan dan mengalami peningkatan keterampilan terkait manajemen keuangan, pemanfaatan modal sosial, dan kemampuan dalam pemasaran digital produk pertanian.
Economic Evaluation of FebriDx®: A Novel Rapid, Point-of-Care Test for Differentiation of Viral versus Bacterial Acute Respiratory Infection in the United States
Authors: Dick Katherine , Schneider John
Published: September 2021

Background: Acute respiratory infections (ARIs) are commonly treated with antibiotics in outpatient settings, but many infections are caused by viruses and antibiotic treatment is therefore inappropriate. FebriDx®, a rapid point-of-care test that can differentiate viral from bacterial infections, can inform antibiotic treatment decisions.

Objectives: The primary aim of this study is to conduct a literature-based US economic evaluation of a novel rapid point-of-care test, FebriDx®, that simultaneously measures two key infection biomarkers, C-reactive protein (CRP) and Myxovirus resistance protein A (MxA), to accurately differentiate viral from bacterial infection.

Methods: A budget impact model was developed based on a review of published literature on antibiotic prescribing for ARIs in the United States. The model considers the cost of antibiotic treatment, antibiotic resistant infections, antibiotic-related adverse events, and point-of-care testing. These costs were extrapolated to estimate savings on a national level.

Results: The expected national cost to treat ARIs under standard of care was US $8.25 billion, whereas the expected national cost of FebriDx point-of-care-guided ARI treatment was US $5.74 billion. Therefore, the expected national savings associated with FebriDx® rapid point-of-care testing was US $2.51 billion annually.

Conclusions: FebriDx, a point of care test that can reliably aid in the differentiation of viral and bacterial infections, can reduce antibiotic misuse and, therefore, antibiotic resistant infections. This results in significant cost savings, driven primarily by the reduction in antibiotic resistant infections.
Biological production of citric acid in submerged culture of Aspergillus niger using cassava pulp wastes
Authors: Ezea Ifenayi Boniface , Ezaka Emmanuel , Iwuagwu Joy Onyekachi , Itubochi Calista Odinachi
Published: September 2021

Utilization of cassava pulp wastes for citric acid production was investigated using Aspergillus niger in a submerged culture. A series of experiments were designed on various fermentation parameters to establish the optimal conditions for citric acid production from cassava pulp. This study revealed that production parameters such as cassava pulp concentration, initial pH, incubation temperature, agitation, and nitrogen source and fermentation period had effect on the amount of citric acid produced from cassava pulp. Citric acid concentration increased as the concentration of cassava pulp increases up to 20% with maximum citric acid concentration of 14.9 ± 0.413 g/l after 120 hours of fermentation. pH 5.5 was the optimum with maximum  citric acid concentration of 16.8 ± 0.23 g/l after 120 hours of fermentation. Incubation temperature at 300 C was the optimum, with citric acid concentration of 19.15 ± 0.43 g/l. Increased in agitation speed from 100 to 225 rpm gave the maximum citric acid concentration of 25.2 ± 0.32 g/l after 120 hours of fermentation. Soybean meal supplementation was the best maximum citric acid concentration of 28.2 ± 0.51 g/l. Evaluating the effect of different concentration of soybean meal shows that 0.3 %  supplementation was the optimum with maximum concentration of 31.2 ±0.35g/l from cassava pulp after 120 hours of fermentation. The result suggested that citric acid can be accumulated using cassava pulp by Aspergillus niger in submerged culture during fermentation. Cassava pulp if well harnessed can be used for large scale citric acid production.
Harnessing Acremonium zonatum (Sawada) Gams oil formulations as water hyacinth control mycoherbicides.
Authors: Mutebi Chrispo , Opande George
Published: September 2021

The effect of formulating Acremonium zonatum (Saw.) Gams in corn oil, mineral oil and glycerol was determined in a glasshouse at Maseno University Botanic Garden and laboratory. The study was situated at latitude -100’ 00’’ S and longitude 340 36’ 00’’E. A. zonatum was aseptically isolated from symptomatic plants and inoculated upon healthy water hyacinth plants in a CRD experiment.  Data was analyzed using SPSS version 20 computer software. Oil and spore density effects were statistically significant at p < 0.05. The main effect of oil yielded an effect size of 0.281 indicating that 28.1 % of the variance in disease severity was explained by the oil formulation (F(2, 28) = 5.459, p = 0.01). Spore density yielded an effect size of 0.326 indicating that 32.6% of the variance in the study was explained by spore density (F(3, 28) = 4.515, p = 0.011). The interaction effect was not significant (F(6, 28) = 0.199, p = 0.974) indicating that there was no combined effect for the kind of oil used in the formulation of the A. zonatum and the spore density. The results suggested that A. zonatum pathogenicity varies with different spore concentrations, 1x 108 spores/ml being the most potent. A. zonatum has favorable characteristics for consideration as a mycoherbicide. Corn oil as formulation material was concluded to be the best formulation material for A. zonatum.
MICROBIAL ASSESSMENT OF FROZEN FOODS SOLD IN AYOBO, LAGOS
Authors: Emmanuel-Akerele Hilda , Uchendu Favour
Published: September 2021

This study seeks to investigate the microbial profile of frozen fish and meat. Forty samples consisting of Scomber scombrus (Titus), Clupea harengus (Shawa) and frozen meat (Chicken, Turkey) were purchased from different retail outlets in Ayobo-Ipaja markets for microbiological analysis.  The samples were analysed for the total viable count using standard microbiological procedures.  The mean bacterial and fungal counts for Scomber scombrus, Chicken, Clupea harengus and Turkey are 254.70±83.81 CFU/G and 5.50±4.45 CFU/G; 210.10±55.03 CFU/G and 6.80±3.39 CFU/G; 298.20±67.35 CFU/G and 6.10±3.87 CFU/G; 221.30±80.33 CFU/G and 4.30±2.00 CFU/G respectively. Clupea harengus has the highest bacterial count while Scomber scombrus has the lowest bacterial count. Chicken has the highest fungal count while Turkey had the lowest fungal count. The microbial isolates from the frozen food samples include species of S. aureus, E. coli, Salmonella, Micrococcus, Aspergillus, and Penicillium. Escherichia coli were susceptible to all the antibiotics while Salmonella sp., Staphylococcus aureus, and Micrococcus were resistance to Augmentin, Gentamycin, Tarivid, and susceptible to Sparfloxacin and Chloramphenicol. Although freezing retard pathogens multiplication, post-harvest contaminants can multiply during thawing to a level that can have a major impact on the quality of the final consumer product. It is advised that frozen foods must be properly cooked before consumption and effective hazard analysis and critical control point implemented.
EFFECTS OF GAS FLARING ON THE MICROBIAL AND PHYSICOCHEMICAL PROPERTIES OF SOILS IN DELTA STATE
Authors: Enuenwemba Joseph , Uraih Nduka , Tanimowo William , Emmanuel-Akerele Hilda
Published: September 2021

This study was carried out to determine the impact of gas flaring on microbial and physicochemical characteristics of soil around Ebedei and Kwale Flow Stations in Delta State, Nigeria. Soil samples were collected around Ebedei, in Ukwuani local government area, and Kwale, in Ndokwe West local government area both in Delta State, as well as in their environs. While the soil samples were collected for the analysis of physical, chemical and biological properties of the soil. The highest concentration of the heavy metals was obtained at 10m away from the flaring sites (P < 0.05). In both Ebedei and Kwale, the Fe concentration is significantly higher (1080.33 and 1080.68 mg/kg, respectively) that the other two heavy metals. However, there was a significant difference in the concentration of Zn between Ebedei and Kwale (P < 0.05). In both Ebedei and Kwale, the ECEC concentration is significantly higher (8.16 and 6.57 meq/100g, respectively) that the other chemical parameters. The physicochemical properties were similar at the different distances away from gas flaring sites (P> 0.05). EC decreased from 119.12µs/cm (at 10m) to 50.4 (at 100m) and then to 44.37 (at 200m). pH value remained acidic ranging from 4.97 (at 10m) to 5.9 (at 200m); moisture content ranged from 3.25% (at 10m) to 5.89% (at 200m); organic matter ranged from 1.07% (at 10m) to 1.61 % (at 200m); NO3 reduced sharply from 10.35 mg/kg (at 10m) to 3.92mg/kg (at 100m) and then to 2.4mg/kg (at 200m); phosphate dropped from 0.91mg/kg at (at 10m) to 0.95mg/kg (at 100m) to 0.42mg/kg (at 200m). There was a significant difference in the amount of some physicochemical properties in the soil samples collected from the gas flaring areas in Ebedei and Kwale (P<0.05). Ebedei, Kwale and environs constitute part of the most vegetative and productive areas of the Niger Delta region, these areas are also rich in several pharmacological properties and water resources. The Government should ensure the enforcement of laws aimed at minimizing the amount of gas flared into the atmosphere. Urgent efforts should be geared at cushioning the effect of gas flaring on the communities affected, probably by compensating them or, by relocating them to a more environmental friendly settlement with compensations.
ISOLATION AND CHARACTERIZATION OF DIESEL DEGRADING BACTERIA FROM PETROLEUM OIL CONTAMINATED SOIL
Authors: Ahmed Tanvir , Alam Sababa , Ahmed Tasnia
Published: September 2021

Petroleum products are used for energy production and an essential part of our day-to-day lives especially in vehicles, ships, and industries. Accidental leakages occur easily and wastage petroleum is also discarded in the environment without any further processing causing environmental pollution. Diesel contributea big part topetroleum pollution. The current study was aimed to identify diesel degrading bacteria and determine some conditions to evaluate their best degradation capability. We identified Aeromonas spp., Bacillus spp., and Enterobacter spp. from diesel contaminated soil and found that Aeromonas spp. and Bacillus spp. grow best with 10% to 15% diesel whereas Enterobacter spp. can grow quite well with 20% diesel concentration at a higher temperature (40oC) than the previous two bacteria. Aeromonas spp. worked well at low pH (pH 4 to pH 6) whereas Bacillus spp. and Enterobacter spp. worked best at higher pH (pH 10).
Accreditation of specialists with higher medical and pharmaceutical education
Authors: Khodus S. V. , Оleksik V. S. , Zverev А. S.
Published: September 2021

The issue of reforming not only the healthcare system as a whole, but also the system of training medical and pharmaceutical personnel is relevant today. The main direction of the National Project "Healthcare" is the solution of the issue of providing healthcare institutions with qualified personnel, the introduction of a system of continuing medical education (the National Project "Healthcare", the federal project "Providing medical organizations of the healthcare system with qualified personnel"). In this regard, the requirements for persons who have mastered educational programs and are engaged in medical activities on the territory of Russia have changed. Admission to medical activity, according to modern trends, should be objective, uniform and universal throughout the country. The aim of this article is familiarization of specialists with higher medical and pharmaceutical education with the legislative framework and methodology for conducting the accreditation procedure for specialists. Primary, primary specialized and periodic accreditation is a complex organizational, methodological and engineering process that requires a competent approach in terms of planning, organization and implementation. The training of employees of accreditation centers according to the programs of training specialists in medical simulation training, as well as close interaction with the accreditation commission, certainly allows us to solve these problems and flawlessly ensure that all stages of accreditation of specialists are carried out.
Comparative characteristics of the quality of life of asthma patients with different types of airway hyperresponsiveness to physical stimules
Authors: Perelman N. L.
Published: September 2021

Aim. To compare the nature and degree of influence of different types of airway hyperresponsiveness (AHR) on the general and specific quality of life (QoL) of patients with asthma and control over the disease.

Materials and methods. 234 patients with mild-to-moderate asthma, aged from 18 to 60 years old, were interviewed and examined. Depending on the presence of one or another type of AHR, 4 groups were formed: group 1 included 60 patients with cold AHR, group 2 – 75 patients with hypoosmotic AHR, group 3 – 35 patients with hyperosmotic AHR, group 4 – 64 patients with exercise-induced bronchoconstriction (EIB). QoL and the state of the emotional sphere were assessed using the SF-36, AQLQ, HADS questionnaires. The level of asthma control was determined using the ACT questionnaire. Lung function was assessed by spirometry.

Results. When comparing QoL between groups, statistical differences were obtained for most of the SF-36 scales, with the exception of the domains “Role Physical” (RP) and “Bodily Pain” (BP), and their presence and significance varied depending on the types of AHR being compared. The lowest QoL indices were found in group 1 of patients with cold AHR according to the domains “Physical Activity” (PA), RP, BP, and “Role Emotional” (RE). The lowest indices for the domains “General Health” (GH), “Vitality” (V) and “Mental health” (MH) were found in the respondents of the 2nd group. Most of the highest QoL indicators in the compared groups were found in patients of group 4 with EIB in the domains PA, RP, V, RE, and MH. When carrying out a comparative analysis, the maximum number of significant differences was found between the groups with cold AHR and EIB. A comparative study of QoL using a special AQLQ questionnaire showed the lowest indices for the “Activity” and “Symptoms” domains in groups 1 and 2 of asthma patients. In addition, in group 1, the minimum QoL values were recorded for the “General QoL” domain (3.6±0.2 points), and in group 2, for the “Environment” domain (2.9±0.3 compared with 3.9±0.2 points in group 3, p<0.01).

Conclusion. This study has demonstrated the multifaceted effect of AHR on health-related QoL, dependent on sensitivity to a particular physical stimulus and the season of maximum trigger action. The subjective assessment of psychosocial functioning is most differentiated according to the GH domain of the SF-36 questionnaire. The greatest negative impact on the QoL indices is exerted by the cold and hypoosmotic AHR, the least – by the EIB. The assessment of QoL allows to get a full picture of the perception of the patient's health level at the moment and in the given conditions.
Ultrastructural characteristics of erythrocytes and their relationship with oxygen transport in patients with ischemic heart disease after coronary artery bypass grafting with artificial circulation
Authors: Sergeev E. A. , Shmelev M. E. , Geltser B. I. , Kotelnikov V. N.
Published: September 2021

Aim. Evaluation of nanostructural and micromechanical characteristics of erythrocytes and their relationship with the parameters of oxygen transport in patients with ischemic heart disease (IHD) after coronary artery bypass grafting (CABG) under artificial circulation (AC).

Materials and methods. The study involved 30 men with IHD aged 53 to 67 years with a median of 63 years, who underwent planned CABG with AC at the clinic of the Far Eastern Federal University. Blood sampling from patients was carried out before the AC and one day after it from a venous catheter located in the right atrium. Erythrocytes were scanned using a Bioscope Catalyst atomic force microscope (AFM) (Bruker, USA) in combination with an Axiovert 200 inverted microscope (Zeiss, Germany). The micromechanical properties of cell membranes were investigated with the PFQNM-LC-A-CAL cantilevers. The following were recorded: the diameter of erythrocytes, the height of their side, area, volume, membrane rigidity, strength of its adhesion, Young's modulus, elastic deformation. To assess oxygen transport, the oxygen delivery index (DO2I), consumption (VO2I), and extraction ratio (O2ER) were calculated.

Results. In one day after CABG, a decrease in DO2I, VO2I, and O2ER was recorded by 14%, 33%, and 16%, respectively, which indicated a limitation in the gas transport function of the blood. Analysis of the AFM characteristics of erythrocytes showed an increase in their area by 35%, in diameter by 6%, in volume by 19%, and the height of the side by 5 times. At the same time, multidirectional changes in the micromechanical properties of erythrocyte membranes were noted: Young's modulus and stiffness decreased by 3.2 and 2 times, respectively; the adhesion force increased by 2.7 times, and the elastic deformation – by 2.2 times. Correlation analysis showed the presence of reliable relationships between indicators of oxygen transport and biomechanical parameters of erythrocyte membranes.

Conclusion. A comprehensive analysis of the nanostructural parameters of erythrocytes and oxygen transport expands the understanding of the pathophysiological mechanisms of postperfusion disorders in patients with coronary artery disease after CABG under conditions of cardiopulmonary bypass.
Implementasi Pengelolaan Badan Usaha Milik Desa (BUMDesa) Jatimakmur Dalam Peningkatan Pendapatan Asli Desa (PADes) Di Desa Jatirejoyoso
Authors: Bin Abdullah Hasbullah
Published: September 2021

The purpose of this study was to determine the implementation of Jatimakmur Village Owned Enterprise Management (BUMDes) in increasing Village Original Income (PADes) in Jatirejoyoso Village. The method used by researchers in this study is descriptive research with a qualitative approach. The data used in this study are primary data and secondary data. Primary data is data from interviews with respondents related to the implementation of Jatimakmur BUMDes management in increasing Jatirejoyoso Village Original Income. According to Article 1 Number (6) of Law Number 6 of 2014 concerning Villages, it is written that Village-Owned Enterprises, hereinafter referred to as BUMDes, are business entities whose entire or most of the capital is owned by separate villages to manage assets, services, and other businesses. for the welfare of rural communities. Then, amended through the Job Creation Act no. 11 of 2020 Article 117 and Article 185 explain that BUMDes is a legal entity established by villages and/or together with villages to manage businesses, assets, develop investment and productivity, provide services, and/or other businesses for the greatest welfare. public. Village Original Income (PADes) is all efforts made by the village government to support the implementation of Village Government in the context of implementing Village autonomy (Law Number 6 of 2014 concerning Villages Article 71). According to the explanation of Law Number 6 of 2014 Article 72 paragraph (1) letter a what is meant by "Original Village Income" is income that comes from village authority in managing village assets based on origin and local scale authority. , results of separated village wealth management, results of self-help, community participation and mutual cooperation, other legitimate village original income (Nurcholis, 2011: 82).
Keywords: Management Implementation, Village Original Income, Village Owned Enterprises.
Strategi Kebijakan Percepatan Perhutanan Sosial Di Provinsi Riau
Authors: A Zulkarnain Ariandi
Published: September 2021

Abstrak: Perhutanan sosial adalah sistem pengelolaan hutan lestari yang dilakukan dalam kawasan hutan negara atau hutan hak/hutan adat yang dilaksanakan oleh masyarakat tempatan dan masyarakat hukum adat sebagai pelaku utama untuk meningkatkan kesejahteraan, keseimbangan lingkungan dan dinamika sosial budaya. Perhutanan sosial menjadi mandat melalui Peraturan Menteri Lingkungan Hidup dan Kehutanan P-83 Tahun 2016 yang merupakan wujud nawacita Presiden Joko Widodo, capaian perhutanan sosial sampai saat ini masih jauh dari target 12,7 juta hektar pada tahun 2019, capaian perhutanan sosial diseluruh Indonesia baru mencapai 1,3 juta hektar. Riau dalam merealisasikan perhutanan sosial sangat lambat, dari 1,4 juta hektar yang ditargetkan untuk Provinsi Riau baru mencapai 83.928 Hektar di tahun 2018. Penelitian ini menggunakan pendekatan kualitatif deskriptif, yakni berusaha menganalisis pengembangan dan strategi percepatan perhutanan sosial (meningkatkan komitmen kebijakan pemerintah daerah, harmonisasi lingkungan kebijakan dan sinergisitas pelaku kebijakan). Tujuan penelitian ini dilakukan guna menganalisis strategi kebijakan percepatan terhadap lambatnya realisasi perhutanan sosial di Provinsi Riau dan mengetahui faktor apa saja yang mempengaruhi kebijakan percepatan perhutanan sosial di Provinsi Riau. Teknik penggalian informasi penelitian ini dengan wawancara mendalam, studi kepustakaan dan observasi.Hasil penelitian ini menunjukkan strategi percepatan perhutanan sosial ditentukan oleh komitmen pemerintah daerah dalam menyiapkan kelembagaan perhutanan sosial baik dalam upaya peningkatan alokasi anggaran, penguatan regulasi, memfasilitasi pengurusan izin dan pembinaan terhadap pengelolaan hutan. Harmonisasi lingkungan kebijakan berupa political will pemimpin daerah dan kondisi sosial ekonomi dipengaruhi oleh politik legilatif DPRD (Perda RTRW) dan iklim ekonomi kelapa sawit mendominasi penguasaan lahan, Selain itu juga penguatan peran serta sinergisitas pelaku kebijakan (Pokja PPS & KPH) sebagai subjek kebijakan menjadi kunci percepatan perhutanan sosial di Provinsi Riau.

Kata Kunci: Strategi, Perhutanan Sosial,  Kebijakan Kehutanan.
The Effect of Word Card Media on the Ability to Write Effective Sentences in Class III Indonesian Language Subjects at SD Negeri Nyantong
Authors: Septiani Awaliya Septia , Sunanih  , Yopa Taufik Saleh
Published: September 2021

The purpose of this study was to examine the effect of word card media on students' writing ability in learning Indonesian for grade 3 SD Negeri Nyantong. This study used an experimental method. This research design was Quasi Experimental Design with Nonequivalent Control Group Design. The study population was 35 respondents and the experimental class sample was 17 people, and the control class was 18 people. Sampling with purposive sampling. Collecting data through interview sheets, tests and documentation. Quantitative data processing is completed through data processing with hypothesis testing. The results of research on students' writing skills in Indonesian subjects using word card media showed differences and increases in the average writing ability of students before and after treatment. With a significance value of 0, 000 <0.05, so the hypothesis is accepted. So it can be concluded that the word card media is effective and influences the writing ability of students in learning Indonesian for grade 3 SD Negeri Nyantong.
The Effect of Contextual Teaching And Learning (CTL) Learning Model Assisted by Android-Based Application Media Whith Thunkable On Learning Interest Of Class V SDN Students Candirejo 02
Authors: Arif Agus Arifin Rohmatullah , Kartika Yuni Purwanti
Published: September 2021

This study aims to determine the effect of contextual teaching and learning (CTL) learning models assisted by android-based applications with thunkable on students' interest in learning. This type of research is an experiment with a pretest - posttest control group design. The population in this study were all students of SDN Candirejo 02, Ungaran Barat District, Semarang Regency, then for the research sample was class 5 SDN Candirejo 02, Ungaran Barat District, Semarang Regency with random sampling techniques. The data collection technique used is the scale of observation, tests, questionnaires (questionnaires) and documentation. Data were analyzed by normality test, homogeneity test, t test and regression test. The results of the research show: (1) There are differences in the use of contextual teaching and learning (CTL) learning models assisted by android-based applications with thunkable on students' learning interest, this is evidenced by the significance level > 0.05, i.e. 0.000 > 0.05 using the t test (2 ) There is an effect of the use of contextual teaching and learning (CTL) learning models assisted by android-based applications with thunkable on students' interest in learning, this is evidenced by a significance level of < 0.05, i.e. 0.000 > 0.05 using a regression test. The results of this study can be concluded that the contextual teaching and learning (CTL) learning model assisted by android-based applications with thunkable has an effect on increasing student interest in learning.