bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS PENGARUH PENDAPATAN PREMI NETO TERHADAP LABA PERUSAHAAN SEKTOR ASURANSI JIWA DI INDONESIA SELAMA PANDEMI
Authors: Mufidah Zahra Utriza
Published: August 2023

Pandemi Covid-19 meningkatkan risiko terhadap jiwa dan kesehatan masyarakat. Masyarakat akan cenderung mencari cara untuk mengurangi risiko dengan mengikuti program asuransi jiwa dan kesehatan. Penelitian ini bertujuan untuk menganalisis pengaruh pendapatan premi neto terhadap laba setelah pajak perusahaan sektor asuransi jiwa yang tergabung dalam Asosiasi Asuransi Jiwa Indonesia selama masa pandemi Covid-19 periode Januari 2019 â€“ Maret 2020 menggunakan korelasi sederhana dan regresi linier sederhana dengan bantuan aplikasi IBM SPSS 26. Metode analisis yang digunakan adalah metode analisis kuantitatif, dengan teknik pengambilan sampel nonprobability sampling. Data yang digunakan adalah data sekunder berupa data statistik asuransi yang diperoleh dari website Otoritas Jasa Keuangan. Hasil uji korelasi sederhana menunjukkan bahwa terdapat hubungan signifikan yang positif antara pendapatan premi neto terhadap laba setelah pajak. Hasil uji hipotesis menunjukkan bahwa pendapatan premi neto berpengaruh signifikan terhadap laba setelah pajak. Setiap peningkatan 1% pada pendapatan premi neto, maka laba setelah pajak industri akan meningkat sebesar 0,016%. Pendapatan premi neto berpengaruh signifikan positif sebesar 33,4% terhadap kenaikan laba setelah pajak yang diterima industri. Untuk pengaruh sebesar 69,6% didapatkan selain dari pendapatan premi neto.
TINJAUAN ATAS PENERAPAN SAK EMKM PADA UMKM GLASS OF DIMENSION
Authors: Shinduprinata Agietz
Published: August 2023

Menyusun laporan keuangan yang relevan dan reliable dapat membantu menentukan strategi bisnis di masa mendatang. Pemilik Usaha Mikro, Kecil, dan Menengah (UMKM) kerap mengalami kebingungan dalam menentukan kebijakan dan rencana strategis karena kurangnya informasi kinerja keuangan yang dimiliki. Laporan keuangan yang informatif juga dapat menjadi sarana bagi pemilik dalam mendapatkan sumber pendanaan yang lebih luas sebagai syarat pengajuan pinjaman. Artikel ini secara khusus berupaya meninjau kesesuaian penerapan Standar Akuntansi Keuangan Entitas Mikro, Kecil, dan Menengah (SAK EMKM) pada laporan keuangan UMKM Glass of Dimension dan menunjukkan pengaruh menyusun laporan keuangan sebagai alat bantu bagi pemilik dalam menentukan kebijakan strategis di masa mendatang. Artikel ini menemukan bahwa metode perhitungan saldo yang dilakukan oleh pemilik untuk menghitung saldo akun-akun pada pos aset sudah sesuai dengan perhitungan yang diatur dalam SAK EMKM, namun belum menyusun laporan keuangan yang sesuai dengan SAK EMKM, sehingga laporan keuangan UMKM Glass of Dimension belum menjadi alat dukung bagi pemilik dalam menentukan kebijakan dan rencana strategis untuk kelangsungan dan ketahanan usahanya.
Pengenaan Pajak Pertambahan Nilai terhadap Obat
Authors: Mulyani Sri
Published: August 2023

Value Added Tax (VAT) is an important for Indonesia. The imposition of VAT on medicine as BKP can increase the purchase price of the medicine. However, medicine is a very important and basic need for public health. So, itâ€™s availability cannot be ignored. The purpose of this study is to review the government's policy on the imposition of VAT on medicine and identify the best treatment and the impact that can be caused by the imposition of VAT on medicine. The author uses a qualitative method with data retrived from a literature study on regulations about VAT on medicine delivery and uses data from interviews with several sources. The conclusion of this study is found that a difference in the imposition of VAT on pharmaceutical installations for medicine delivery, for outpatients are still subject to a 10% tariff, while inpatients are not subject to VAT because they are part of health services which are non taxable. The imposition of VAT on medicine has the potential to increase selling prices and reduce the level of access and utilization by the public. However, if VAT on medicine is abolished or reduced, there will be potential crimes by irresponsible parties.
ERGONOMICALLY ANTHROPOMETRIC BODY MASS INDEX (BMI) MEASURING SYSTEM
Authors: Erinle Tunji John , J. Olorunfemi Bayode , Olorunnishola Akim Abayomi
Published: August 2023

The study focused on ergonomically anthropometric body mass index (BMI) measuring system for medical check-ups and maintenance of the human body system's health status. The aim of the study is to develop an ergonomically anthropometric BMI measuring system for medical check-up and upkeep of the human body system's health status. This study covers the estimation of the human body mass index (BMI) of any weight up to 180 kilograms and a height up to 2.1 m. The materials involved in the developed of the BMI measuring system under study are: Load Cells with Strain Gauge, Sonar with Ultrasonic Sensors, Liquid Crystal Displays (LCD), Medium Density Fibreboard (MDF), Microcontroller Arduino Board, and Battery. The system consists of a frame, a platform stand, and a control switch. The performance evaluation was done to measure the system functionality and the results were based on its operation. The results revealed by the performance evaluation of the system that the average weight and height for male and female were measured at 64.4 kg and 169.7 cm, and 54.3 kg and 159.7 cm respectively. The percentage of humans with BMI normal weight is 80 %, and that of BMI underweight is 20 %. The efficiency of the system is 99.94 %.
Analyzing Urban Network Patterns for Efficient Pedestrian Movement in Dadong
Authors: Majid Hassan
Published: August 2023

Analyzing Urban Network Patterns for Efficient Pedestrian Movement in Dadong
Integrating Urban Network Analysis into Community Design for Low-Carbon Living
Authors: Majid Hassan
Published: August 2023

Integrating Urban Network Analysis into Community Design forLow-Carbon Living
Urban Network Analysis for Sustainable Community Pedestrian Network Design
Authors: Majid Hassan
Published: August 2023

Urban Network Analysis for Sustainable Community PedestrianNetwork Design
Critical Quantitative Literacy: An Educational Foundation for Critical Quantitative Research
Authors: Frisby Michael Blake
Published: August 2023

Education research has recently seen the emergence of two distinct frameworks guiding the application of quantitative methods through a more critical and equity-oriented lens. These two frameworks are critical quantitative (CritQuant) studies, and quantitative Critical Race Theory (QuantCRiT). Though different in their intellectual traditions, they are allied in acknowledging the oppressive history of quantitative methods and improving the criticality of quantitative research in education. In order for applied quantitative research in education to become more critical, it is imperative that learners of quantitative methodology must be made aware of its historical and modern misuses. This calls for an important change in the way quantitative methodology is taught in educational classrooms. Critical quantitative literacy (CQL) is introduced in this manuscript as a paradigm for teaching, learning, understanding, and applying quantitative methods in a way that supports the application of CritQuant and QuantCRiT frameworks in educational research.
Complex diachronies of final nasalization in Austronesian and Dakota
Authors: Dąbkowski Maksymilian , Begus Gasper
Published: August 2023

Final nasalization of voiced stops is phonetically unmotivated (i. e. not a consequence of universal articulatory or perceptual tendencies). As such, final nasalization has been deemed an impossible sound change. Nonetheless, Blust (2005, 2016) proposes that final nasalization took place in four Austronesian languages: Kayan-Murik, Berawan dialects, Kalabakan Murut, and Karo Batak. In this paper, we argue final nasalization in these languages is not a single sound change and reduce it to a combination of phonetically grounded changes. We demonstrate that in Austronesian, final nasalization involved four steps: (i) fricativization of voiced stops, (ii) devoicing of the fricatives, (iii) spontaneous nasalization before voiceless fricatives, and (iv) occlusion of the nasalized fricatives to nasal stops. Finally, we extend our account to final nasalization in Dakota (Siouan) and propose a new explanation for the development of the unnatural final voicing in the related Lakota language. Our results shed light on the role of phonetic naturalness in diachrony and synchrony. We maintain that while phonetically unnatural phonological processes may arise via a sequence of sound changes or analogical extension, sound changes are always natural and phonetically grounded.
Childhood Trauma is Associated with Early-Onset but not Late-Onset Suicidal Behavior in Late-Life Depression
Authors: Chang Ya-Wen , Buerke Morgan , Galfalvy Hanga , Szanto Katalin
Published: August 2023

Objectives: To examine the relationship between childhood traumatic experiences and early and late-onset suicidal behavior among depressed older adults.Design: Cross-sectional study.Setting: Inpatient and outpatient psychiatric services in Pennsylvania.Participants: Our sample included 224 adults aged 50+ (M±SD = 62.5±7.4) recruited into three depressed groups: 1) 84 suicide attempters, 2) 44 suicide ideators, and 3) 58 non-suicidal comparisons, and a non-psychiatric healthy comparison group (N = 38).Measurements: The Childhood Trauma Questionnaire measured experiences of childhood trauma such as emotional abuse, physical abuse, emotional neglect, physical neglect, and sexual abuse. Results: Attempters were separated into early- and late- onset based on age of first attempt using a statistical algorithm that identified a cutoff age of 30 years old. Overall, we found group differences in emotional and physical abuse and neglect in both genders and in sexual abuse in females, but not in males. Early-onset attempters experienced more childhood emotional abuse and neglect than late-onset attempters, and were more likely to have experienced multiple forms of abuse. They also experienced more emotional abuse and neglect than all comparison groups. Consistently, early-onset attempters more often met criteria for current or lifetime PTSD relative to late-onset attempters and most comparison groups. Late-onset attempters had similar levels of childhood trauma as other depressed groups.Conclusions: Our study reaffirms that there are distinct pathways to suicidal behavior in older adults based on their age of first suicide attempt, and that trauma experienced in childhood has long-lasting emotional and behavioral consequences, even into late life.
Age at first birth and women's midlife health: Cohort and race differences across the 20th century
Authors: Wolfe Joseph D. , Thomeer Mieke Beth , Reczek Corinne
Published: August 2023

We test whether the association between socially “early” childbearing and women's health in later adulthood, well-established in prior research, differs across distinct historical contexts in the U.S.We further examine whether socioeconomic status explains this shift in the impact of childbearing timing and poor health and whether there are additional differences across racial groups. To address these questions, we pooled data from two nationally representative longitudinal surveys: the National Longitudinal Surveys’ Mature Women (born 1922–1937) and Youth 1979 (born 1957–1964). Together, these NLS cohorts include women who entered adolescence before and after the major economic, political, and demographic changes in the latter half of the twentieth century that gave women access to socioeconomic structures previously limited to White men. These data thus provide a unique opportunity to test cohort and racial differences. Overall, findings suggest that the negative association of young childbearing, which included adolescent childbearing and childbearing in early 20s, with midlife health grew across the two cohorts, with this largely explained by differences in adult educational attainment. This cohort shift appeared especially large for White women compared to Black women. This study highlights the importance of sociopolitical context in shaping the health consequences of major life events like childbearing.
Women and Animals in Anita Desai’s Fire on the Mountain: A Study of Violence
Authors: Neupane Ravindra
Published: August 2023

This paper examines the novel Fire on the Mountain by Anita Desai within the context of materialist postcolonial ecofeminism. Despite the fact that both women and animals are excluded from society, I contend that the "other" in the shape of both women and animals is the focus of the book. Through the story, the author reframes topics like women and animals which are typically discussed through the male perspective. The woman serves as the interpreter between humans and animals. The animal figure is used to mediate self-politics and relationships between the two sexes. I demonstrate the significance of the ambivalent viewpoint when discussing the novel's protagonists. These ladies do not fall into either the cultural or natural domains in the culture-nature dichotomy. They demonstrate their ambivalence about both the culture/nature notions by straddling the binary in-between. No demeaning romantic or celebratory association exists between women and the natural world or with animals. The issue of violence against both women and animals has been looked at within this paradigm.
Study Regarding Exploring the Position of Women in Rajasthani or Marwari Folk Tales
Authors: Kushwah Anurag
Published: August 2023

Rajasthani and Marwari folk tales are rich cultural repositories that provide valuable insights into the societal norms, beliefs, and values of the region. This paper aims to investigate the position of women in Rajasthani or Marwari folk tales, shedding light on their roles, representation, and significance within these narratives. By analyzing a diverse range of folk tales, this study aims to uncover the portrayal of women and explore the dynamics of gender relationships in Rajasthani and Marwari folklore. Through a comprehensive examination of these narratives, this research aims to contribute to a deeper understanding of the cultural fabric and social dynamics prevalent in Rajasthan and Marwar.
Insulin secretion in liver transplant recipients following conversion to a prolonged release tacrolimus formulation
Authors: Peretz David , Faisal Nabiha , Uhanova Julia , Schacter Isanne , McAlpine Diane , Knowles Cori , Minuk Gerald Y
Published: August 2023

Background:

Post liver transplant diabetes mellitus (PLTDM) occurs in 10–40% of liver transplant recipients and is associated with increased morbidity and mortality. An important cause of PLTDM is tacrolimus induced, concentration-dependent, inhibition of insulin secretion.

Objective:

To determine if a newly licenced formulation of tacrolimus (Envarsus-PA), which achieves peak tacrolimus concentrations 20–30% lower than other tacrolimus formulations has less of an inhibitory effect on insulin secretion.

Methods:

Homeostatic model assessment (HOMA) for insulin secretion (HOMA-S) values and c-peptide levels were determined in 19 adult liver transplant recipients while being maintained on immediate- or slow-release tacrolimus formulations and repeated a minimum of 30 days following conversion to Envarsus-PA.

Results:

Insulin secretion was unchanged following conversion to Envarsus-PA (HOMA-S pre-conversion: 154 ± 133 vs. 129 ± 75, post-conversion [ p = 0.32], and c-peptide levels; 1059 ± 602 and 934 ± 463 respectively, p = 0.42). Fasting blood glucose (FBG) and hemoglobin A1c (HbA1c) levels were also unchanged (FBG 5.7 ± 0.8 pre-conversion vs. 5.6 ± 0.7 post-conversion; p = 0.36 and HbA1c 4.9±1.2 pre-conversion versus 5.5±0.2 post-conversion, p = 0.34).

Conclusions:

Envarsus-PA had no significant effect on insulin secretion or glucose homeostasis beyond that associated with other tacrolimus formulations in adult liver transplant recipients.
Cómo obtener mosaicos u orlas de personas en el Directorio EXIT [How to get tiles or mosaics of people in the EXIT Directory]
Authors: Baiget Tomàs
Published: August 2023

Se detalla como obtener mosaicos de personas en el Directorio de Expertos en el Tratamiento de la Información (Directorio EXIT). La selección puede hacerse a partir de los miembros de un país, provincia, ciudad, institución y materia o especialidad. Es una opción muy interesante para recordar nombres de personas cuyo aspecto físico se conoce.
ECONOMICS: THE COMPLETION OF THE “DISPUTE OF TWO CAMBRIDGES”
Authors: Grodskiy Vladimir
Published: August 2023

The monograph for the first time comprehensively investigates two main areas of modern economics - mainstream and ‘neo-Ricardianism’, which are in a state of the so-called ‘dispute of two Cambridges’. The theoretical advantages and disadvantages of the directions are shown, as well as specific proposals for their synthesis. The author’s interpretations of many issues of economic theory are presented, aimed at increasing its consistency, logical persistence and predictability of further development.
Addressed to researchers, graduate students and teachers, specializing in the field of economics.
Manajemen Ekstrakurikuler Muhadharah di Madrasah Aliyah
Authors: Izzati Izzati , Fauzi Muhammad , Isnaini Muhammad
Published: August 2023

This article has used a type of qualitative research with a descriptive research approach (case study) because it describes management or descriptive interpretation of the extracurricular management of muhadharah at Madrasah Aliyah Patra Mandiri Plaju Palembang. The main data sources in this study were interview data with the Head of the Madrasah, Deputy Head of Curriculum, Deputy Head of Student Affairs, teachers and Muhadharah extracurricular coaches, and 18 student representatives from each class. The findings of this study are: Planning (Planning) extracurricular muhadharah is going well as seen by involving all components responsible for the stability of activities carried out to achieve madrasa objectives, such as by holding meetings, determining classes, schedules, materials, and so on. Coaches and teachers who function as human resources for extracurricular muhadharah activities can carry out their duties properly. The implementation (actuating) of extracurricular muhadharah activities shows that madrasa leaders/representatives are less proactive in providing motivation that can generate enthusiasm at work. Supervision (controlling) extracurricular muhadharah activities at Patra Mandiri Plaju Palembang Madrasah Aliyah, this activity did not run optimally because the madrasa leadership did not formally request a written report on the activities carried out, and informally the leadership did not ask for an explanation verbally or directly on activities that have been carried out.
Pelaksanaan Pembelajaran Tahfidz Al-Qur`An Dalam Membentuk Karakter Islami Siswa
Authors: Alwi Toto , Badaruddin Kms , Febriyanti Febriyanti
Published: August 2023

This study aims to determine the Learning of Tahfidz Al-Qur`an in shaping the Islamic character of Students at SD IT Islahul Ummah Prabumulih City. Learning evaluation The research was conducted at SD IT Islahul Ummah, Prabumulih City, 2022 to 2023. The research subjects were Tahfidz Al-Qur`an tutors, Madrasa Heads, Administrative Staff, and students of SD IT Islahul Ummah, Prabumulih City. This type of research is qualitative research. Data collection was carried out through interviews, observation, and document studies. All data collected was then analyzed in two stages. The first stage was when the data collection process was in progress, and the second stage after all data was collected was then analyzed by means of descriptive analytic. From this research, it was obtained an explanation that: 1) The Al-Qur'an tahfidz Learning Curriculum has been applied in the form of a syllabus 2). In learning, the supervising teachers have made a written plan, letters that must be memorized, 3). Implementation of Al-Qur'an Tahfidz Learning is carried out outside of class hours. 4). The method of memorizing the Qur'an uses the muroja`ah and sima`i methods. 4). The supervising teacher has a great influence on students in learning Taffid Al-Qur`an. 6). Learning Evaluation is carried out for each student's memorization deposit to the supervising teacher.
Manajemen Pembelajaran Fiqih Dengan Media Youtube Untuk Meningkatkan Minat Belajar Siswa
Authors: Oktaviani Amanda Eka , Istikomah Istikomah
Published: August 2023

Teaching and learning activities in the current digital era must master internet technology with various platforms including fiqh learning. Fiqh learning is a compulsory subject for all levels of education. In the management of fiqh learning, educators are required to have the ability to modify the learning process, therefore, fiqh learning material will be liked and find it interesting for students. The purpose of this study is to describe the management of fiqh learning with YouTube media. This research is a type of qualitative research with a case study approach. Data collection techniques were carried out by means of interviews, observations, and documentation in this research. It states that the management of learning fiqh at MI Roudlotul Ulum is carried out in accordance with the learning mechanism and based on the desired learning objectives. The achievement of good learning outcomes depends on the ability of educators to manage learning.
Pengembangan Media Digital Berbasis Flipbook Untuk Meningkatkan Kemampuan Berpikir Kritis Pada Peserta Didik
Authors: Prasasti Riska Dwi , Anas Nirwana
Published: August 2023

This study aims to improve critical thinking skills in students in class IV Mis Al-Furqon Klumpang Kebun in Social Science (IPS) subjects using flipbook media that has been developed. The type of research used is research and development (RnD), which is research used to develop a particular product and test the effectiveness of the product. Media development in this study used the ADDIE research design, which is a development model consisting of five stages including analysis, design, development, implementation, and evaluation. This research develops a product in the form of Flipbook-based digital media on Social Studies subjects which is then tested for feasibility by material experts, media experts, and Class IV students of MIS Al- Furqon Klumpang Kebun. The subjects of this study were 18 fourth grade students. The object of this research is the development of flipbook-based digital media. Based on the results of this research and development, it is concluded that this flipbook-based digital media meets the assessment criteria that have been proven by the material validation score with a score of 3.5 and a media validation score of 4.0 with a recapitulation result of 3.75 which is included in the very valid category. This shows that flipbook-based digital media is included in valid criteria and is suitable for use as teaching materials for teachers and students
The Development of Web-Based Image Puzzle Media for Madrasah Tsanawiyah Students
Authors: Tarigan Nur Rizky , Ahkas Akmal Walad
Published: August 2023

One of the learning media which can be used in mufrodat learning (Arabic vocabulary) is a web-based image puzzle. However, in reality, the educator that uses web-based learning media in learning Arabic still needs to be found. This research is development research (RnD) which aims to develop web-based image puzzle media for mufrodat learning (Arabic vocabulary) for VIII grade of MTs students and determine its feasibility through validation and practicality tests. The research model uses a 4-D model that has been modified to 3-D, which is divided into three stages; define (definition), design (design), and development (development). The research instruments include validation sheets to measure product feasibility, interviews with subject teachers, and student response questionnaires to measure the level of product practicality. Web-based image puzzle media obtains a score of 3.5 in material validation and a score of 3.6 from media validation that meets the valid category. Based on the student response questionnaire, web-based image puzzle media obtains a practicality percentage of 76% which categorizes in the excellent category. Therefore, web-based image puzzle media in mufrodat learning (Arabic vocabulary) can be feasible and practical for the learning process.
Reduksi Kejenuhan Belajar Sejarah Kebudayaan Islam; Analisis Variasi Metode dan Media Pembelajaran Berbasis Digital
Authors: Siddik Mhd. Fajar , Mahariah Mahariah
Published: August 2023

This study aims to determine the emergence of learning obstacles experienced by students at MAS PAB 4 Klumpang. This research uses qualitative methods with the type of field research and descriptive methods. Data collection by observation, interviews, and documentation. This study produced several findings, namely: (1) Factors causing saturation of learning SKI (History of Islamic Culture) experienced by grade XI students include: experiencing fatigue in the body due to carrying out routine activities, fatigue felt by limbs such as fingers and toes due to a lot of writing, looking weak and there are students who put their heads on the table when the teacher is explaining due to the teacher's lack of attention to Students, experiencing lazy learning due to food intake that is not good for the body and the absence of effective methods carried out by teachers. (2) Variations of digital-based learning methods and media in reducing SKI learning saturation by Giving Assignments to Students, Increasing Teacher Attention to Students, Learning Outside the Classroom, Adding Reading Resources or SKI Learning References (3) Learning achievement with a variety of digital-based learning methods and media in MAS PAB 4 Klumpang schools. Personalized Learning, Breadth of Information, More Interesting Lessons,  Develop Accountability, Learning Flexibility, Recorded Content, 24-Hour Resources, Connected Learning, Easily Track Student Progress, and Improve Written Language Skills.
Pengaruh Model Discovery Learning Terhadap Hasil Belajar Pendidikan Agama Islam Siswa
Authors: Pahmi Alwan Sadni , Albina Meyniar
Published: August 2023

The purpose of this research is to investigate whether or not the discovery learning model improves students' knowledge of Islamic religious education while they are enrolled in class X at SMA Negeri 3 Kutacane. Experimental quantitative research is used in this study, and the research method that is utilized is a quasi-experimental design. Class X IPA 1 will serve as the experimental class, while class X IPA 2 will play the role of the control class in this research design. Both a Pre-test and a Post-test are included in the testing procedure for the research. On the basis of the findings of the research, a reliability value of 0.550 exceeded the r-table threshold of 0.05. When the sig value for testing the hypothesis is acquired and it is found to be 0.001 more than 0.005, the hypothesis H0 is found to be false. It is possible to draw the conclusion that there is a substantial gap between the learning outcomes attained by students in the experimental class who utilized the discovery learning model and those of students in the control class who utilized the traditional learning model.
Evaluation of Computer Training Programs Using Models Kirkpatrick to Increase the Competency Capacity of PerGunu Teachers
Authors: Mustofa Ihsan , Kuswara Heri , Rosmawati Rosmawati , Rosmika Enita
Published: August 2023

Computers have very multi-tasking functions. Computers can help complete various jobs, one of which is that they can be used in the teaching and learning process. With the sophistication of hardware and software on computers, teachers can present attractive, interesting, and fun learning methods and models. Unfortunately, not all teachers can make the most of computers as a solution in their teaching and learning process. One of them happened to teachers who were members of the Nahdlatul Ulama Teachers' Association (Pergunu) in Lampung Province. Therefore, the Regional Board of the Nahdlatul Ulama Teachers Association of Lampung Province has carried out computer training program activities for Gunu teachers. To determine the extent to which the success of this training can be felt by the participants, researchers conducted research on this computer training program using the Kirkpatrick model or what is known as the Kirkpatrick Four Levels Evaluation Model, namely evaluating the effectiveness of Kirkpatrick's training program by evaluating training programs based on four stages of evaluation, namely: 1) reaction, 2) learning, 3) behavior, and 4) results. This evaluation was carried out as an effort to improve computer training programs in the future so as to be able to increase the competency capacity of teachers in optimizing computers as a means of successful learning. The results of the research that has been carried out on this Computer Training Program, meanwhile, show that participants get the benefits to be applied in the learning process.
Student Management in Improving Arabic Communication Competence and its Implications for Students Self Determination
Authors: Rumania Siti , Maulana Asep , Irawan Bambang , Uthman Yusuf Olawale Owa-Onire
Published: August 2023

This article aims to describe the management of students carried out by teachers at the As-Sunniah Kencong Islamic Boarding School for all students to master Arabic materials to help improve their ability to communicate in Arabic and the implications for student self-determination learning. The research approach used is qualitative research. Data collection techniques utilize observation, interviews, and documentation studies. In this study, researchers used several stages of data analysis, namely the reduction stage, the data presentation stage, making temporary conclusions, and verification activities. The study results concluded that two hours of lessons are scheduled weekly with material according to the level. Meanwhile, the management of students outside the classroom includes Daily Arabic Conversation, Arabic Speech Practice, and Arabic Speech Contests. The management of students in learning Arabic at the As-Sunniah Kencong Islamic Boarding School is that the learning systems and methods are pretty good and effective, learning is in line with Arabic learning theories, the awareness and interest of the students to speak Arabic have grown, and language environment has been built.
LEFT VENTRICULAR REMODELING IN HEART FAILURE (PART ІI): PHENOTYPIC HETEROGENEITY AS A RATIONALE FOR PERSONALIZED PATIENTS` MANAGEMENT
Authors: Chursina T.Ya. , Kravchenko A.M. , Mikhaliev K.O.
Published: August 2023

Aim: to provide a literature review of the current conсepts on phenotypic heterogeneity of left ventricular (LV) remodeling in heart failure (HF), and highlight the significance of such a diversity for an implementation of personalized patients` management. This paper is a second part of the review, devoted to the current state of pathophysiology of LV remodeling in HF.

Material and methods. The thematic scientific papers, published predominantly during the last decade, constituted the study material. The research methodology involved bibliosemantic method and structural and logical analysis.

Results and discussion. HF is a heterogeneous, multifactorial and rising epidemic syndrome. To date, the LV ejection fraction (EF) is used as a substantial criterion for HF classification and management. However, the existing research data has revealed the significant overlapping between different LV EF-based HF patterns in terms of the risk factors, comorbidities and disease modifiers; bidirectional transitions of LV EF due to disease treatment and progression; myocardial fibrosis and dysfunction; effectiveness of neurohumoral inhibitors etc.

Moreover, the «spectrum» paradigm has been recently proposed, positioning HF as a spectrum across different phenotypes. Particularly, each HF phenotype is the result of a patient-specific trajectory, being an exceptional and unique «track» for the heart transition towards different remodeling patterns.

The HF phenotyping may be an innovative approach to the study of myocardial remodeling and HF, which is potentially an important prerequisite for the development of individualized patients` treatment. Personalized medicine can offer the particular options for managing HF patients, that, in turn, will better identify responders, non-responders, and those at high risk of adverse events, and ultimately improve of the treatment efficacy and safety.

Conclusions. The baseline heterogeneity of the structural and functional patients` characteristics, including those describing the LV remodeling, and their dynamic change over time, creates a spectrum across overlapping HF phenotypes, challenging a categorical HF classification based solely on LV EF. Such an approach to treat the HF phenotypic heterogeneity may provide further insights into the pathomechanisms, related to LV remodeling in HF, and has the potential to improve the personalized patients` management.
Effectiveness of pain treatment for patients with mine-blast wounds depending on the number of localizations in military mobile hospitals
Authors: Horoshko V.R. , Kuchyn Iu.L.
Published: August 2023

Patients with gunshot wounds suffer from chronic pain in 70% of cases, and those with mine-blast wounds – in 83.3% of cases. Civilian patients, after serious injuries, in 11-40% of cases. Unfortunately, there is not enough data to study the causes of such a high frequency of pain chronicity. Therefore, the study of the results of pain treatment at the stage of treatment in military mobile hospitals may be able to reveal the reasons for such a high frequency of chronicity.

Methods. The treatment of 280 patients with mine-blast wounds was analyzed. The intensity of pain was diagnosed using a visual analog scale. The Shapiro-Wilk test was used to check the distribution of quantitative indicators for normality. The law of distribution differed from the normal one, the median value (Me) and interquartile range (QI-QIII) were given to present quantitative indicators, and the comparison of indicators in the two groups was performed by the Mann-Whitney test. To analyze the dynamics of indicators, the Friedman criterion for linked samples was used, and the posterior comparison was performed using the Bonferroni correction. For qualitative indicators, the absolute frequency of the trait and the relative frequency (%) are presented, and the chi-square test with the correction for continuity was used to compare the two groups. In all cases, the critical level of significance was set at 0.05.

Results. The analysis of pain intensity according to the VAS, before anesthesia, upon admission to military mobile hospitals, showed that patients experienced high-intensity pain reaching 7 points. This indicates a lack of effective pain control both at the initial stage of treatment and during evacuation. After anesthesia, VAS data indicate the presence of moderate pain – 4 points. The intervals between analgesic treatments averaged 6 hours. Although the effectiveness of analgesia according to VAS was low.

Conclusions. Patients with mine-blast injuries have a very high risk of chronic pain – 57.5% higher than in injured patients in civilian life. The study results point to ways to improve treatment outcomes for this category of patients. Achieving high-quality pain control at the stage of treatment in military mobile hospitals and maintaining the continuity of treatment during an evacuation can potentially reduce the incidence of pain chronicity.
ARTERIAL HYPERTENSION AMONG MEDICAL WORKERS. ANALYSIS. EVALUATION
Authors: Tolstanov О. K. , Gordienko L. M.
Published: August 2023

The aim. To examine the impact of individual medical and social factors, including work experience, lifestyle and living conditions, excess body weight, metabolic syndrome, types of circadian rhythms of blood pressure, and heredity, on the frequency of arterial hypertension (hypertensive disease - HD) formation.

Materials and methods. The study involved the collection of anamnestic data, conducting interviews, performing objective examinations, and monitoring blood pressure in 391 medical workers, predominantly from therapeutic, surgical, and intensive care backgrounds. The obtained data were statistically processed using probability assessment criteria, risks assessed through odds ratio (OR), and ROC analysis.

The results. The study revealed that only 33% of medical workers have a normal body weight. The risk of developing hypertensive disease (HD) is 3.24 times higher in the group with excess body weight and 8.72 times higher in the group with obesity compared to the examined subjects with normal body weight (p<0.0001). Daily blood pressure monitoring results showed a statistically significant difference in 12 out of the 21 studied parameters (p<0.05) between patients with HD, with and without metabolic syndrome. This indicates that the presence of metabolic syndrome affects the severity of hypertensive disease. Additionally, a statistically significant difference (p<0.05) was observed in the distribution of circadian rhythm types of blood pressure between groups with and without hypertension. It was established that there is a predominance of unfavorable types of circadian blood pressure rhythm in medical worker groups experiencing high professional psycho-emotional stress (78.1-85.5%). Recognizing the risk factors for HD occurrence in medical workers can significantly enhance the effectiveness of a comprehensive hypertensive disease prevention program, leading to reduced blood pressure levels and a lower frequency of complications.

Conclusions. It has been established that excess body weight is a risk factor for the development of hypertensive disease (HD) in medical personnel. The presence of metabolic syndrome has been proven to affect the severity of the hypertensive disease course. There is a certain association between disruptions in circadian blood pressure rhythms, professional psycho-emotional stress, and the development of arterial hypertension in medical workers of certain specialties. The prognostically significant threshold level of work experience for the formation of a group at an increased risk of developing HD is 11 years.
CLINICAL AND LABORATORY FEATURES OF THE COURSE OF CHRONIC VIRAL HEPATITIS B AND C IN CHILDREN OF PODILSKY REGION: POSSIBILITY FOR MODERN MONITORING
Authors: Nezgoda I. , Demchyshyn Y.
Published: August 2023

Introduction. In modern hepatology, a special place is occupied by chronic viral hepatitis, including B and C, because today they occupy the leading positions due to their high prevalence, the possibility of severe complications, and also they could lead to death in both adults and children. Specialists should have a comprehensive understanding of the clinical course and laboratory diagnosis of viral hepatitis to facilitate timely diagnosis and effective management of this condition.

The aim: to evaluate the clinical and laboratory features of the course of chronic viral hepatitis B and C in children by determining patterns between parametric indexes characterizing the processes of liver fibrosis.

Materials and methods. In the process of scientific research, 49 children were examined, including 29 children with diagnosed chronic viral hepatitis B and C (group I) and 20 almost healthy children (group II). The diagnoses of CHB and CHC were confirmed by the PCR method and specific markers detected by ELISA. All examined patients underwent anamnesis collection, general clinical examination, laboratory examination, calculation of CDS, Lok, GUCI, APRI, FIB-4 and "Fibrotest" diagnostic indexes. Statistical data analysis was carried out with "R-Studio" and "Statistica 10.0" software, using the methods of descriptive statistics, correlation analysis. Significance was considered significant at p<0.05. The study was conducted in compliance with the principles of the Declaration of Helsinki.

Results. It was established that the levels of ALT, AST, GGT, ALP, indirect bilirubin, international normalized ratio (INR) were significantly higher in the examined patients of the I group. The level of the CDS index was significantly higher in the examined patients of the I group (5,97±0,30), compared with the patients of the II group (4,35±0,28) (p<0,001). A similar trend was noted with the Lok index and FIB-4 (p<0,001). The GUCI and APRI indices were significantly higher in patients of the I group (1,02±0,22; 0,73±0,04), compared to the examined patients of the II group (0,27±0,02; 0,23±0,02) (p<0,01).

Conclusions. Implementation of non-invasive indices into clinical practice for the management of children with chronic hepatitis B and C will allow for dynamic monitoring of liver fibrogenesis processes.
Comparing the attitudes, norms, and beliefs of husbands and wives for reproductive, maternal, and child health—Evidence that drives effective social behavior change programming in Kebbi State
Authors:   Breakthrough RESEARCH
Published: August 2023

This brief provides rigorous evidence-based insights to implementers and researchers of social and behavior change (SBC) programs that seek to improve community knowledge, attitudes, norms and behaviors for improved health of pregnant and postpartum women. The brief focuses on key behaviors including early breastfeeding initiation within one hour of birth and exclusive breastfeeding for the first six months of life, while also uncovering the barriers and facilitators to the practice of these positive health behaviors. It is one of a series that presents findings from a Breakthrough RESEARCH study that uniquely captures data on a wide range of psychosocial drivers of behavioral outcomes in the areas of family planning, malaria, and maternal, newborn and child health, and nutrition.
Loss of cervical lordosis in chronic neck pain patients with fibromyalgia: A cross-sectional study
Authors: Delen Veysel , İlter Server
Published: August 2023

BACKGROUND: Some interrelationships among fibromyalgia (FM), loss of cervical lordosis (LCL), and headache have been reported. Thus, it is sensible to examine LCL as a factor underlying FM and headache. OBJECTIVE: In this study we aimed to assess LCL in chronic neck pain patients (CNPP) with FM and its association with headache features and FM severity. METHODS: CNPP with (n= 55; mean age 40.0 ± 8.5; range 20 to 55 years) and without FM (n= 55; mean age 38.5 ± 8.9; range 20 to 55 years) were included in the study. Cervical lordosis was assessed by measuring the Cobb angle on the lateral cervical radiographs. The patients were asked about headache features within the last month. In addition, the CNPP with FM were evaluated by the Turkish version of the Revised Fibromyalgia Impact Questionnaire. RESULTS: There were no statistically significant differences between the groups in terms of age, weight, height, body mass index, working status, and neck pain duration (p> 0.05 for each). The CNPP with FM had significantly reduced cervical lordosis angle compared with those without. The CNPP with FM had significantly higher headache frequency than those without (p= 0.008). There was statistically significant negative correlation between cervical lordosis angle and headache frequency in the CNPP with FM (r: -0.336; p= 0.012). CONCLUSION: According to the results of this study, LCL may be associated with FM and headache frequency in the CNPP with FM.
Lower subcutaneous fat index predicts bone metastasis in breast cancer
Authors: Wang Wen , Huang Wen-Juan , Liu Ping-Ping , Fu Shuang , Zhang Meng-Lin , Zhang Xin , Wang Rui-Tao , Huang Yuan-Xi
Published: August 2023

BACKGROUND: Bone metastases affect 50% to 70% of breast cancer (BC) patients and have a high mortality rate. Adipose tissue loss plays a pivotal role in the progression of cancer. OBJECTIVE: This study aims to evaluate the prognostic value of adipose tissue for bone metastasis in BC patients. METHODS: 517 BC patients were studied retrospectively. Patients’ characteristics before the surgery were collected. Quantitative measurements of the subcutaneous fat index (SFI) were performed at the level of the eleventh thoracic vertebra. In order to adjust for the heterogeneity between the low SFI and high SFI groups, propensity score matching (PSM) was used. The Kaplan-Meier method was used to estimate the 5-year bone metastatic incidence. The prognostic analysis was performed with the Cox regression models. RESULTS: Compared with the patients without bone metastasis, the patients with bone metastasis had reduced SFI levels. In addition, Kaplan-Meier analysis revealed that patients with low SFI were more likely to develop bone metastases. The independent predictive value of SFI for bone metastases was confirmed by Cox regression analysis. The survival analysis was repeated after PSM with a 1:1 ratio, yielding similar results (P< 0.05). CONCLUSIONS: SFI is an independent predictor of bone metastasis in BC patients.
Increased expression of LINC00323 correlates with tumor progression and poor prognosis of gastric cancer
Authors: Zhu Si-Yu , Li Jin-Jie , Lu Qin , Yang Chao , Ma Lei , Jin Chuan , Cui Shu-Zhong , Fu Ji-Ding , Zeng Li-Si , Yang Xian-Zi
Published: August 2023

BACKGROUD/AIMS: LINC00323 is a novel lncRNA which has reported to play an important role in the development and recurrence in several cancers. However, the expression and predictive value of LINC00323 in gastric cancer (GC) remain mysterious. METHODS: LINC00323 expression in GC tissues and adjacent normal tissues was evaluated by quantitative reverse-transcription PCR (qRT-PCR). The relationship between LINC00323 expression and clinicopathological features and patients’ survival were analyzed. Univariate and multivariate survival analyses were performed. RESULTS: LINC00323 expression were found to be significantly increased in GC tissues. High expression of LINC00323 exerted a pro-tumor effect in the late stage of GC development. Kaplan-Meier analysis showed that patients with high LINC00323 were associated with poor overall survival (OS) and progression-free survival (PFS). Moreover, the combination of TNM stage and drinking status better identified GC patient outcome than those of TNM stage alone. CONCLUSIONS: Our data showed that LINC00323 overexpression might serve as a novel independent prognostic factor for survival of GC patients, suggesting LINC00323 was a potential biomarker and therapeutic target for GC.
TRB CDR3-cancer testis antigen chemical complementarity scoring for identifying productive immune responses in renal cell carcinoma
Authors: Hudock Tabitha R. , Barker Vayda R. , Manley Brandon J. , Chobrutskiy Andrea , Chobrutskiy Boris I. , Diaz Michael J. , Song Joanna J. , Blanck George
Published: August 2023

BACKGROUND: Immunogenomics approaches to the characterization of renal cell carcinoma (RCC) have helped to better our understanding of the features of RCC immune dysfunction. However, much is still unknown with regard to specific immune interactions and their impact in the tumor microenvironment. OBJECTIVE: This study applied chemical complementarity scoring for the TRB complementarity determining region-3 (CDR3) amino acid sequences and cancer testis antigens (CTAs) to determine whether such complementarity correlated with survival and the expression of immune marker genes. METHODS: TRB recombination reads from RCC tumor samples from RNAseq files obtained from two separate databases, Moffitt Cancer Center and The Cancer Genome Atlas (TCGA), were evaluated. Chemical complementarity scores (CSs) were calculated for TRB CDR3-CTA pairs and survival assessments based on those CSs were performed. RESULTS: Moffitt Cancer Center and TCGA cases representing the upper 50th percentile of chemical CSs for TRB CDR3 amino acid sequences and the CTA POTEA were found to be associated with a better overall survival (OS) Also, greater tumor RNA expression of multiple immune signature genes, including granzyme A, granzyme B, and interferon-gamma were correlated with the higher chemical CSs. CONCLUSIONS: These results indicate that TRB CDR3-CTA chemical complementarity scoring may be useful in distinguishing RCC cases with a productive, anti-tumor immune response from cases where basic immune parameter assessments are inconsistent with a productive immune response.