bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of sodium hyaluronate combined with rehabilitation training on knee joint injury caused by golf
Authors: Chen Li-Ke , Yu Qin-Ming
Published: June 2024

BACKGROUND

In high-intensity sports like golf, knee joints are prone to injury, leading to pain, limited mobility, and decreased quality of life. Traditional treatment methods typically involve rehabilitation exercises, but their effectiveness may be limited. In recent years, sodium hyaluronate has emerged as a widely used biomedical material in the treatment of joint diseases.

AIM

To explore the effect of sodium hyaluronate combined with rehabilitation training on pain degree, flexion range of motion and motor function of knee joint injured by golf.

METHODS

Eighty patients with knee joint injury caused by golf were randomly divided into control (group B) and observation group (group A). The group B was treated with rehabilitation training, and the group A was treated with sodium hyaluronate combined with rehabilitation training. The clinical efficacy, range of motion and function of knee joint, quality of life and inflammatory factors were compared.

RESULTS

The excellent and good rate of rehabilitation in the group A was raised than group B. At 6 weeks and 3 months after treatment, the range of motion of the two groups was raised than that before treatment, and that of the group A was raised than group B. After treatment, the scores of Lysholm and International Knee Documentation Committee (IKDC) in the group A were raised, and those in the group A were raised than group B. The VAS score of the two groups was reduced than that of the group B, and the SF-36 score of the group A was reduced than group B. The interleukin (IL)-1 β, IL-8 and tumor necrosis factor-α in the two groups were reduced, and those in the group A were reduced than group B.

CONCLUSION

Sodium hyaluronate combined with rehabilitation training has a good clinical effect in the treatment of patients with knee joint injury caused by golf, which relieve pain, maintain knee joint function and improve patients' life quality.
Effect of dienogest treatment on uterine fibroid volume in patients with endometriosis or adenomyosis complicated by uterine fibroids
Authors: Zhang De-Yu , Huang Yan , Peng Chao , Zhou Ying-Fang
Published: June 2024

BACKGROUND

Currently, the use of dienogest in clinical practice has increased significantly, and many studies have focused on its effectiveness and safety in the treatment of endometriosis and adenomyosis; however, the effects of treatment with dienogest on uterine fibroid size in patients with endometriosis or adenomyosis have not been investigated.

AIM

To explore changes in fibroid size in patients with concomitant uterine fibroids undergoing dienogest treatment for endometriosis or adenomyosis and to evaluate the effectiveness and safety of the drug.

METHODS

The clinical data of patients with uterine fibroids treated with dienogest for endometriosis or adenomyosis at Peking University First Hospital from January 2021 to January 2023 were retrospectively analyzed.

RESULTS

The maximum uterine fibroid diameter and volume increased after 3 months, 6 months and 1 year of dienogest treatment compared with those before treatment (P < 0.01). The maximum diameter and volume of the uterine adenomyoma increased after 3 months of dienogest treatment but decreased after 6 months and 1 year of treatment compared with those before treatment, but the difference was not significant (P > 0.05). Endometrial thickness and antigen 125 levels were significantly thinner and decreased, respectively, after dienogest treatment (P < 0.01). Pearson's correlation analysis revealed that the increase in uterine fibroid volume after 3 months of dienogest treatment was positively correlated with the basic uterine fibroid volume (r = 0.792, P < 0.01). Among 64 patients with dysmenorrhea, 63 experienced significant relief of dysmenorrhea after 6 months of treatment with dienogest, and all patients experienced significant relief of dysmenorrhea after 12 months. Patients were able to tolerate the drugs, with an average drug tolerance score of 8.73.

CONCLUSION

The use of dienogest in patients with endometriosis or adenomyosis combined with uterine fibroids can effectively relieve the patient's pain symptoms and significantly reduce the sizes of ovarian endometriotic cysts, but it cannot inhibit uterine fibroid growth.
Comparative study on emotional behavior and parental job stress of only-child and non-only-child preschool children
Authors: Fu Zhi-Wei , Wang Kai-Li , Du Ning-Yu , Li Yue-Jing , Duan Jing-Jing , Zhao Sheng-Xia
Published: June 2024

BACKGROUND

Studies have revealed that Children's psychological, behavioral, and emotional problems are easily influenced by the family environment. In recent years, the family structure in China has undergone significant changes, with more families having two or three children.

AIM

To explore the relationship between emotional behavior and parental job stress in only preschool and non-only preschool children.

METHODS

Children aged 3-6 in kindergartens in four main urban areas of Shijiazhuang were selected by stratified sampling for a questionnaire and divided into only and non-only child groups. Their emotional behaviors and parental pressure were compared. Only and non-only children were paired in a 1:1 ratio by class and age (difference less than or equal to 6 months), and the matched data were compared. The relationship between children's emotional behavior and parents' job stress before and after matching was analyzed.

RESULTS

Before matching, the mother's occupation, children's personality characteristics, and children's rearing patterns differed between the groups (P < 0.05). After matching 550 pairs, differences in the children's parenting styles remained. There were significant differences in children's gender and parents' attitudes toward children between the two groups. The Strengths and Difficulties Questionnaire (SDQ) scores of children in the only child group and the Parenting Stress Index-Short Form (PSI-SF) scores of parents were significantly lower than those in the non-only child group (P < 0.05). Pearson’s correlation analysis showed that after matching, there was a positive correlation between children's parenting style and parents' attitudes toward their children (r = 0.096, P < 0.01), and the PSI-SF score was positively correlated with children's gender, parents' attitudes toward their children, and SDQ scores (r = 0.077, 0.193, 0.172, 0.222).

CONCLUSION

Preschool children's emotional behavior and parental pressure were significantly higher in multi-child families. Parental pressure in differently structured families was associated with many factors, and preschool children's emotional behavior was positively correlated with parental pressure.
Efficacy and safety of over-the-scope-clips in the therapy of acute nonvariceal upper gastrointestinal bleeding: Meta-analysis
Authors: Yang Xue-Zhu , Yu Dan-Li , Wang Zhi , Gao Zhi-Long
Published: June 2024

BACKGROUND

Acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) is a frequent life-threatening acute condition in gastroenterology associated with high morbidity and mortality. Over-the-scope-clip (OTSC) is a new endoscopic hemostasis technique, which is being used in ANVUGIB and is more effective.

AIM

To summarize and analyze the effects of the OTSC in prevention of recurrent bleeding, clinical success rate, procedure time, hospital stay, and adverse events in the treatment of ANVUGIB, to evaluate whether OTSC can replace standard endoscopic therapy as a new generation of treatment for ANVUGIB.

METHODS

The literature related to OTSC and standard therapy for ANVUGIB published before January 2023 was searched in PubMed, Web of Science, EMBASE, Cochrane, Google, and CNKI databases. Changes in recurrent bleeding (7 or 30 days), clinical results (clinical success rate, conversion rate to surgery, mortality), therapy time (procedure time, hospital stay), and adverse events in the OTSC intervention group were summarized and analyzed, and the MD or OR of 95%CI is calculated by Review Manager 5.3.

RESULTS

This meta-analysis involved 11 studies with 1266 patients. Total risk of bias was moderate-to-high. For patients in the OTSC group, 7- and 30-days recurrent bleeding rates, as well as procedure time, hospital stay, and intensive care unit stay, were greatly inhibited. OTSC could significantly improve the clinical success rate of ANVUGIB. OTSC therapy did not cause serious adverse and was effective in reducing patient mortality.

CONCLUSION

OTSC may provide more rapid and sustained hemostasis, and thus, promote recovery and reduce mortality in patients with ANVUGIB. In addition, the safety of OTSC is assured.
Efficacy and safety of fecal microbiota transplantation for treatment of ulcerative colitis: A post-consensus systematic review and meta-analysis
Authors: Zhang Jin-Tao , Zhang Nan , Dong Xue-Tao , Wang Xiao-Ran , Ma Hong-Wen , Liu Yan-Di , Li Mu-Ran
Published: June 2024

BACKGROUND

Numerous studies have assessed the efficacy and safety of fecal microbiota transplantation (FMT) as a therapy for ulcerative colitis (UC). However, the treatment processes and outcomes of these studies vary.

AIM

To evaluate the efficacy and safety of FMT for treating UC by conducting a systematic meta-analysis.

METHODS

The inclusion criteria involved reports of adult patients with UC treated with FMT, while studies that did not report clinical outcomes or that included patients with infection were excluded. Clinical remission (CR) and endoscopic remission (ER) were the primary and secondary outcomes, respectively.

RESULTS

We included nine studies retrieved from five electronic databases. The FMT group had better CR than the control group [relative risk (RR) = 1.53; 95% confidence interval (CI): 1.19-1.94; P < 0.0008]. ER was statistically significantly different between the two groups (RR = 2.80; 95%CI: 1.93-4.05; P < 0.00001). Adverse events did not differ significantly between the two groups.

CONCLUSION

FMT demonstrates favorable performance and safety; however, well-designed randomized clinical trials are still needed before the widespread use of FMT can be recommended. Furthermore, standardizing the FMT process is urgently needed for improved safety and efficacy.
Visual analysis of abdominal aortitis treatment using the CiteSpace bibliometric method
Authors: Guo Si-En , Meng Yuan-Biao , Zhang Zan-Man , Zhang Yu-Lan , Yao Qi-Sen , Qin Xiao
Published: June 2024

BACKGROUND

Abdominal aortitis can induce aneurysms, and tumor rupture can lead to organ ischemia or even sudden death. At present, there is a lack of extensive understanding and identification of key problems in the treatment of abdominal aortitis, which needs to be further analyzed using bibliometric analysis.

AIM

To discuss the research hotspot and development trend of abdominal aortitis treatment.

METHODS

We searched the English literature (published from 1 January 2000 to 12 March 2024) on the treatment of abdominal aortitis in the Web of Science database. Then, we identified and screened duplicate literature using CiteSpace 6.1R2 software. We conducted an analysis of the number of papers, a co-occurrence analysis of the authors and institutions, and co-occurrence and cluster analyses of the keywords. Then, we drew the author, institution, and keywords of the studies into graphs for visualization. Finally, we expounded on the author, institutional network interactions, and hot keywords of the studies on the treatment of abdominal aortitis.

RESULTS

We included 210 English literature articles involving 190 authors; the author cooperation team was mainly represented by Caradu Caroline, Berard Xavier, Lu Guanyi, Harada Kenichi, and Sharma Ashish K. In the keyword analysis, high-frequency keywords include abdominal aortic aneurysm (38), abdominal aorta (24), Takayasu arteritis (22), etc . The three most central keywords were disease (0.69), classification (0.68), and abdominal aortic aneurysm (0.55). The first nine clusters of keywords are case report, abdominal aortic aneurysm, Takayasu arteritis, dyspnea hematuria, aortic elastic, IgG4-related disease, report, mid aortic dysplastic syndrome, and statin. In the keyword emergent analysis, 14 emergent words were obtained. Among them, seven keywords with strong abruptness were Takayasu arteritis, abdominal aortic aneurysm, disease, retroperitoneal fibrosis, expression, management, and large vessel vasculitis. In the past 3 years, the incidences of abdominal aortic aneurysm (intensity: 4.62) and inflammation (intensity: 1.99) were higher.

CONCLUSION

The number of published papers is on the increase, but the cooperation among authors is scattered. The research focus is mainly on the pathogenesis and treatment of abdominal aortitis-related diseases.
Trends and frontiers in signal amplification for aptamer-based tumor detection: A bibliometric analysis
Authors: Cai Dan , Chen Gui-Lin , Wang Ting , Zhang Kun-He
Published: June 2024

BACKGROUND

Malignant tumors are one of the leading causes of death worldwide, imposing a substantial economic and social burden. Early detection is the key to improving cure rates and reducing mortality rates, which requires the development of sensitive early detection technologies. Signal amplification techniques play a crucial role in aptamer-based early detection of tumors and are increasingly garnering attention from researchers.

AIM

To investigate the current research status, developmental trajectories, and hotspots in signal amplification for aptamer-based tumor detection through bibliometric analysis.

METHODS

English publications pertaining to signal amplification in aptamer-based tumor detection were retrieved from the Web of Science Core Collection database. VOSviewer and CiteSpace software were employed to analyze various information within this field, including countries, institutions, authors, co-cited authors, journals, co-cited journals, cited references, and keywords.

RESULTS

A total of 757 publications were included in this study. China accounted for 85.47% of all publications, with Nanjing University (China) emerging as the institution with the highest publication output. The most influential authors and journals were Hasanzadeh M. from Iran and "Biosensors and Bioelectronics ", respectively. Exosomes and carcinoembryonic antigen (CEA) stood out as the most researched tumor-related molecules. Currently, the predominant signal amplification technique, nanomaterial, and signal transduction method were identified as hybridization chain reactions, gold nanoparticles, and electrochemical methods, respectively. Over the past 3 years, exosomes, CEA, electrochemical biosensors, and nanosheets have emerged as research hotspots, exhibiting a robust burst of intensity.

CONCLUSION

This study is the first bibliometric analysis of literature on signal amplification in aptamer-based tumor detection and elucidates the current status, hotspots, and prospective research directions within this realm. Additionally, it provides an important reference for researchers.
Torsed retroperitoneal leiomyomas: A case report and review of literature
Authors: Li Jin , Zhu-Ge Yi-Yi , Lin Kai-Qing
Published: June 2024

BACKGROUND

Retroperitoneal leiomyomas (RLs) are rare benign tumours that can occur in the pelvic and/or abdominal parietal retroperitoneum. Once torsion occurs, it causes acute abdominal pain and can even lead to serious consequences such as gangrene, peritonitis, haemoperitoneum and shock if not identified and treated promptly. Therefore, a better understanding of the characteristics of RL torsion is needed. Here, we present a case of acute pedicle torsion of an RL in the posterior peritoneum followed by a literature review.

CASE SUMMARY

Herein, we report the case of a 42-year-old woman with RL torsion. The patient visited our hospital complaining of lower abdominal pain for 6 d. Pelvic examination revealed a tender mass superior to the uterus. Pelvic MRI revealed an anterior uterine mass, multiple uterine fibroids and slight pelvic effusion. MRI suggested the possibility of a subserosal myoma of the anterior uterine wall with degeneration. Intraoperative exploration revealed a 10 cm pedunculated mass arising from the posterior peritoneum, with the pedicle torsed two times. Pathological examination confirmed a torsed RL.

CONCLUSION

In the case of a pelvic mass complicated with acute abdomen, the possibility of torsion should be considered.
Non-steroidal anti-inflammatory drugs in postoperative hand fracture management: Do they positively or negatively impact recovery?
Authors: Gorgy Andrew , Dalfen Jacqueline , Barone Natasha , Efanov Johnny I
Published: June 2024

This editorial explores the impact of non-steroidal anti-inflammatory drugs (NSAIDs) on postoperative recovery in hand fracture patients, amidst shifting pain management strategies away from opioids due to their adverse effects. With hand fractures being significantly common and postoperative pain management crucial for recovery, the potential of NSAIDs offers a non-addictive pain control alternative. However, the controversy over NSAIDs' effects on bone healing—stemming from their Cyclooxygenase-2 inhibition and associated risks of fracture non-union or delayed union—necessitates further investigation. Despite a comprehensive literature search, the study finds a lack of specific research on NSAIDs in postoperative hand fracture management, highlighting an urgent need for future studies to balance their benefits against possible risks.
Only a Snowball’s Chance in Hell: Comment on A Call for Change in Healthcare Governance
Authors: Parides George
Published: June 2024

Dr. Robbins’ is 100% correct of what should happen. The proposed changes would be great for patients and practitioners. Unfortunately, there is only a snowball’s chance in hell that any of these things could happen and here are my observations as to why. 1. First, and foremost what is happening now is what the government, Centers for Medicare and Medicaid Services (CMS) and all hospital systems want to happen. They want full, and I mean FULL control of all physicians. It is why they reimburse physicians who work for hospitals (owned by hospitals) more than they do in private practice. They therefore control the votes for Chief of Staff as they are now a large majority of staff members fully owned and because they won't risk their incomes they will vote as told. A private physician has little chance in these elections. 2. Second, when you call on the Joint ...
‘Donne moy ce crochet que j’arrache le reste!’: Witchcraft and Gender-Based Violence in the Poetry of Pierre de Ronsard, Agrippa d’Aubigné, and Mathurin Régnier
Authors: Evelyn Ryan J.
Published: June 2024

Abstract: New and exciting scholarship continues to enrich our understanding of gender and identity politics imbricated in the history of witchcraft in France. Demonologies have provided ample evidence for scholars to develop sound arguments about the relationship between witch-hunts and deep-rooted misogyny. In addition to demonologies as frequently cited sources of anti-woman sentiment, poetry penned by intellectuals offer fertile ground for a reconsideration of the (female) witch as a multivalent figure constantly confined by the male gaze whose passivity runs contrary to the aggression she embodies in demonologies. This article considers the passivity, abjection, and brutalization of female witches in three poems by Pierre de Ronsard (1524–1585), Agrippa d’Aubigné (1552–1630), and Mathurin Régnier (1573–1613). In comparison to demonologies that portrayed witches as destructive forces capable of enacting maleficia, I focus on the witch as a passive creature confined by the male gaze of the speaker-poet. The depiction of the witch as a disparaged and dehumanized social Other whose body is poked, prodded, and mutilated at the hands of a male aggressor challenges the stereotype of aggression promulgated by sixteenth century French demonologies.
Xenon plasma-focused ion beam milling for fabrication of high-purity, bright single-photon sources operating in the C-band
Authors: Mrowinski Pawel , Jaworski Maciej , Sek Grzegorz , Syperek Marcin , Burakowski Marek , Holewa Pawel , Semenova Elizaveta , Zeidler Laura
Published: June 2024

Electron beam lithography is a standard method for fabricating photonic micro and nanostructures around semiconductor quantum dots (QDs), which are crucial for efficient single and indistinguishable photon sources in quantum information processing. However, this technique is difficult for direct 3D control of the structure shape, complicating the design and enlarging the 2D footprint to suppress in-plane photon leakage while directing photons into the collecting lens aperture. Here, we present an alternative approach to employ Xenon plasma-focused ion beam (Xe-PFIB) technology as a reliable method for the 3D shaping of photonic structures containing low-density self-assembled InAs/InP quantum dots emitting in the C-band range of the 3rd telecommunication window. The method is optimized to minimize the possible ion-beam-induced material degradation, which allows to explore both non-deterministic and deterministic fabrication approaches, resulting in photonic structures naturally shaped as truncated cones. As a demonstration, we fabricate mesas using a heterogeneously integrated structure with a QDs membrane atop an aluminum mirror and silicon substrate. Finite-difference time-domain simulations show that the angled sidewalls significantly increase the emission collection efficiency to the level of approx. 0.9 for NA = 0.65. We demonstrate experimentally a high purity of pulsed single-photon emission (~99%) and a high extraction efficiency of η = 0.24, with the latter surpassing the highest reported values in the C-band.
Garcinia indica Leaf Extract Derived Ag-Zn Nanocomposites: A Sustainable Approach for Textile Dyes Photodegradation
Authors: Kurian J.T. , Joseph K.S.
Published: June 2024

The recent advancements for the biosynthesis of nanoparticles from plant biomass offer a promising avenue for the sustainable and environmentally friendly production of nanomaterials. The utilization of plant extracts as bioreductants and capping agents leverages naturally occurring biomolecules for the controlled synthesis of nanoparticles, minimizing environmental impacts and promoting a more sustainable nanotechnology landscape. This study explores the biofabrication of silver-zinc nanocomposites (Ag-Zn NCs) using Garcinia indica leaf extract, offering a green and sustainable alternative to conventional methods. The synthesized nanocomposites were characterized using UV-vis, FTIR, XRD and TEM analyses. The UV-vis spectra confirmed the formation of nanocomposites with distinct surface plasmon resonance peaks (355 nm and 408 nm). FTIR identified functional groups involved in the bioreduction, while XRD indicated a crystalline size of 6.26 nm. TEM images revealed a mixture of hexagonal, spherical and rod-shaped nanocomposites with an average size of 40.37 nm. Furthermore, the study evaluated the photocatalytic activity of the Ag-Zn NCs against various reactive textile dyes (RY-86, RY-145, RB-220 and RB-222). Remarkably, the nanoparticles achieved an impressive 87-100% degradation of these dyes within 160-320 min under UV irradiation. This highlights the potential of biofabricated Ag-Zn NCs for environmental remediation, particularly in treating dye contaminated industrial effluents. This work demonstrates the feasibility of using G. indica leaf extract for the sustainable synthesis of Ag-Zn NCs with efficient dye degradation capabilities.
Selective Sensing and Determination of Cu2+ Ions in Environmental Samples with Newly Prepared Quinoline based Chemosensors and Confirmation of Results using DFT Molecular Modelling
Authors: Obaiah G.O. , Abdulzahra M.A. , Tewari A. , Patel M.S. , Talismanov V.S. , Sharma N.K. , Sehlangia S. , Thakare M.S.
Published: June 2024

An efficient turn-off-fluorescence chemosensing method has been developed to detect Cu2+ ions in a variety of samples. Two new quinoline-based chemosensors (QC1 and QC2) have been prepared under the condensation reaction of 8-quinolinecarboxylic acid with derivatives of L-valine. The synthesized chemosensors were characterized by spectroscopic techniques such as 1H NMR, UV, IR, HRMS and CHNS. The HOMO-LUMO orbitals and energy-minimized structures of the chemosensors were developed. The interaction of metal ions with chemosensors and stable structures of complexes were investigated using DFT. The photoluminescence analysis of both chemosensors (QC1 and QC2) showed the fluorescence emission wavelengths on 495 and 512 nm, respectively, for QC1 and QC2. The change in fluorescence emission wavelengths depends on the electronic effects of the substituents on the quinoline ring. The chemosensors showed a high sensitivity for Cu ions; thus, the detection was exhibited in nanomolar levels. The chemosensing studies were performed in the presence of different metal ions and samples taken from other sources.
Solvothermal Synthesis of Cuprous Oxide Microsphere and its Application as Catalyst for Synthesis of β-Hydroxy Triazole
Authors: Rai Randhir , Saha Saurav , Ravi Sreeshma , Abbas Ameena
Published: June 2024

In this article, the solvothermal synthesis of spherical cuprous oxide microsphere in glycerol-water (1:1) using copper(II) acetate as copper precursor is reported. The synthesized cuprous oxide microparticles was characterized by powder X-ray diffraction (PXRD) and scanning electron microscopic technique (SEM). The material was successfully used as a catalyst for the synthesis of β-hydroxy-1,2,3-triazole in water via a one-pot multicomponent reaction.
Performance and Evaluation of Ionic Liquids as Viscosity Reducers on Indian Crude Oil
Authors: Patel Jinal , Patel Zarana , Nagar Ashish
Published: June 2024

The high viscosity of unconventional oil is one of the main problems with this kind of fuel, which has seen a dramatic surge in output as a result of the energy crisis. A number of transportation deficiencies are observed because of the high viscosity and tight emulsion of unconventional oil which in turn results in economic drifts in the petroleum industries. The work pertains to inhibit the complex components present in crude oil using new generation green chemicals i.e. ionic liquids has been employed to improve the viscosity of the crude oil. Asphaltene clumping can be adhered by the ionic liquids with long alkyl chains attributable to the π–π* interactions and hydrogen bonds formation between them. A series of four alkyl imidazolium based ionic liquids products along with dodecyl-benzene sulphonic acid (DBSA); DIL1, DIL2, DIL3 and DIL4, were obtained with yields of approximately 80, 83, 85 and 85%, respectively, which were characterized through FT-IR and 1H NMR. The synthesized products were evaluated on crude oil having API gravity of 28.57º and pour point 30 ºC. To study the behaviour of crude oil along with additives, pour point studies and theological studies followed by absorbance studies through UV-visible spectrometer for asphaltene onset precipitation was performed. It was found that the synthesized ionic liquids work as viscosity reducers and reduces the viscosity of crude oil upto 78%.
Synthesis, Characterization and Applications of Some Lanthanide(III) Complexes with Schiff Base Derived from L-Valine and Vanillin
Authors: Shyni B. , Remiya J.P. , Sikha T.S.
Published: June 2024

Three lanthanide complexes of Sm(III), Nd(III) and Dy(III) with Schiff base ligand, potassium 2-((4-hydroxy-3-methoxybenzylidene)amino)-3-methylbutanoate derived from the condensation of vanillin and L-valine have been successfully synthesized by solid-state method. The elemental analysis, and spectral studies, such as CHN analysis, FT-IR & FIR, UV-Visible, HR-MS, TG/DTG analysis, photoluminescent spectra and conductivity measurements, were employed for the comprehensive characterization of these compounds. These data indicate that the synthesized Schiff base ligand act as tridentate (ONO) manner towards the metal ions. Additionally, diverse biological activities such as antimicrobial, antioxidant, antidiabetic, anti-inflammatory and larvicidal activities of the ligand and its lanthanide(III) complexes were analyzed.
Antibacterial and Antiviral Potential of Zirconium Oxide Nanoparticle using Extract of Chloranthus erectus Leaf
Authors: Hasan Nor' Aishah , Wazir Nurul Natasha , Zainal-Abidin Nurhamimah , Nawahwi Mohd Zaini , Badrol Hisham Nurul Atikah , Yasin Yamin , Nik Masdek Nik Rozlin , Khairat Jasmine Elanie , Yu Lim Zhi , Azzeme Azzreena Mohamad , Arief Syukri , Putri Gusliani Eka , Ahmad Nor Monica
Published: June 2024

Zirconium oxide nanoparticles (ZrO2 NPs) were synthesized with an effective capping agent using aqueous extract of Chlorentus erectus at the optimized conditions. The aqueous leaf extract contained phytochemical compounds that could regulate the size and shape of the nanoparticles. The average size of C. erectus-ZrO2 NPs crystallite was 10.42 nm, which was determined based on Scherrer Debye’s equation. The finding indicated the effectiveness of the phytochemical compounds to diminish the agglomeration of the particles. The C. erectus mediated ZrO2 NPs were in spherical clusters when observed through a transmission electron microscope (TEM). An elemental energy diffraction X-ray (EDX) assessment also revealed a significant zirconium and oxygen percentage, suggesting that the phytochemicals present in the leaf extract did not alter the purity of C. erectus-ZrO2 NPs. Moreover, 200 µg/mL of synthesized ZrO2 NPs effectively inhibited K. pneumoniae. Up to 300 µg/mL of C. erectus- ZrO2 NPs demonstrated non-toxicity to vero cells and low antiviral properties against the DENV-2 virus when introduced to cells post-infection.
A Facile Route to Catalytic Degradation of Polystyrene over Zeolite and Barium Carbonate
Authors: Das Mukta , Ahsan Nazia , Susan Md A.B.H. , Reza Atek , Jalalah Mohammed , Rashed Md. A. , Sultana Sharmin , Sarker Ashis K.
Published: June 2024

The present work investigated the catalytic degradation of polystyrene over zeolite and barium carbonate catalysts under heat reflux. The spectroscopic analysis confirmed the formation of alkyl benzene on degradation of polystyrene over both zeolite and BaCO3 catalysts. The thermal stability of the polystyrene products after degradation was found to be lower compared to the pure polystyrene. The crystallinity and morphology of the polystyrene products before and after degradation were also examined using X-ray diffraction and scanning electron microscopy. In addition, a plausible mechanism of the degradation pathway of polystyrene over zeolite and BaCO3 was elucidated. The degradation of polystyrene over zeolite produced ethyl benzene and cumene with a high selectivity while styrene monomer was obtained in degradation of polystyrene catalyzed by BaCO3.
Photocatalytic and Conductivity Studies of Proton Exchanged Defect Pyrochlore, KMn0.33Te1.67O6 and its Application in Pb2+ Removal
Authors: Siddikha Asha , Vithal Muga , Sathyanarayana Boodida
Published: June 2024

Ion-conducting oxide materials have incredible technological importance, particularly in devices such as sensors, fuel cells and steam electrolysis cells. In this work, a new proton exchanged defect pyrochlore, HMn0.33Te1.67O6 (HMnTeO), was synthesized by ion-exchange method at room temperature by dissolving KMn0.33Te1.67O6 (KMnTeO) in 5 M HCl solution for 48 h. It was thoroughly characterized by powder-XRD, FESEM-EDX, TEM-HRTEM, FT-IR, Raman, TGA, UV-Vis DRS, PL and XPS techniques. The photocatalytic and DC conductivity of HMnTeO were compared with parent KMnTeO material. The protonated form (HMnTeO) exhibits higher photocatalytic activity against methylene blue degradation and superior DC conductivity compared to parent KMnTeO. The participation of radical species in dye degradation was investigated through scavenger and terephthalic experiments. Based on the results obtained, a probable mechanism was also proposed. Removal of Pb2+ ions from aqueous Pb(NO3)2 was also accomplished using parent KMnTeO.
A Cross-Sectional Study Examining Hyoid Bone Fusion and Density Variation among Patients Receiving Care at a Tertiary Hospital
Authors: Yashas Ullas Lokesha  , Arun Kamireddy  , Shashi Bhushan Singh  , Meghadeepa Srinivasa  , Rahul Deep G.  , Revanth Ravindra Bhat  , Druvadeep Srinivas
Published: June 2024

BACKGROUND
Present research was conducted to the assess extent of hyoid bone fusion in different age groups and genders, and also to assess the developmental changes in hyoid bone mineral density (BMD).
METHODS
This cross-sectional study was carried out in the Radiology Department at Sri Devaraj Urs Medical College. A 3-D model of the hyoid bone was created using computed tomography of 417 patients. Hyoid bones were classified based on the rank of fusion on each side into one of four categories based on fusion: bilateral fusion, unilateral or partial fusion, bilateral non-fusion and bilateral distant non-fusion. Bone mineral density was evaluated using Hounsfield units (HU). The type of fusion and BMD were considered dependent variables whereas Age and sex were considered as independent variables. Statistical significance was established at a threshold of p-value < 0.05. Statistical analysis was conducted using the coGuide software.
RESULTS
Majority of the participants were in age group of >50 years (36.21%). Males were more represented compared to females (62.35%). In the analyzed sample, there was no statistically significant association between gender and the type of fusion across all age groups individually or collectively (p-value>0.05). However, there was statistically significant difference in median BMD between genders across various age categories (p-value <0.05).
CONCLUSIONS
Hyoid bone mineral density was higher in males compared to females and increased with ,age up to 50 years. No specific pattern of hyoid bone fusion was observed across various age groups and genders.
Endoscopic Excision of Pineal Region Epidermoid Cyst
Authors: Hrushikesh Kharosekar  , Vernon Velho
Published: June 2024

A 45-year-old female patient presented to us with a severe headache and vomiting. Neurologically, she was intact. Her MRI brain was done, which showed a lesion in the pineal region which showed restrictions on diffusion weighted images suggestive of an epidermoid cyst. She underwent surgery, a suboccipital craniotomy in a sitting position with a supracerebellar infratentorial approach, endoscopically to completely excise the tumour. The endoscopic approach provided a direct end to vision through a small craniotomy. We could also view and completely excise flakes of epidermoid cysts from hidden areas. The post-operative course was uneventful, and she was discharged without any deficits. A post-operative CT scan of the brain showed complete excision of lesion.
A Comparative Study of Maternal and Foetal Outcome between Reversed Breech Extraction Technique and Foetal Pillow, During Caesarean Section in Full Dilatation (CSFD), In Second Stage of Labour
Authors: Mini Sengupta  , Shaon Dutta
Published: June 2024

The above article has been retracted.
Original Citation-
Sengupta M, Dutta S. A comparative study of maternal and foetal outcome between reversed breech extraction technique and foetal pillow, during caesarean section in full dilatation (CSFD), in second stage of labour. J. Evolution Med. Dent. Sci. 2019;8(18):1463-1468,
DOI: 10.14260/jemds/2019/326
The Development of a Problem-based Learning Physics Module to Facilitate the Critical Thinking Skills of SHS Learners for the Material of Work and Energy
Authors: Nabila Annifa El Firis
Published: June 2024

This research aims to develop a physics module based on problem-based learning to improve high school students' critical thinking skills in work and energy. The research also aims to evaluate the quality of the module and obtain student responses to its use. This research uses a 4D model, namely define, design, develop, and disseminate. The development stage only includes the development stage with extensive testing. There were 10 students randomly selected from classes XI Math and Science 2 and 4 for the limited trial phase, while 35 students from class XI Math and Science 3 for the extensive trial. The research instrument consists of a validation sheet, assessment sheet, and response questionnaire sheet. Module evaluation and student responses are presented in checklist form. The results of this research are: (1) producing a physics module based on a problem-based learning model to facilitate high school students critical thinking skills on the subject of work and energy, (2) the quality of the module that has been developed according to material experts, media experts and physics teachers is Very Good with the respective mean scores being 3.46, 3.58 and 3.74, and (3) the student's response to the module being developed was Agree with the mean score on the limited trial being 0.97 and on the extensive trial being 0.90. Thus, the development of a physics module based on problem-based learning to facilitate high school students' critical thinking skills on the subject of work and energy is suitable for use in physics learning.
Development of Multi Representative Physics E-Module with the Materials of the Momentum and Impulse Grade X High School/Islamic High School Students
Authors: Ramadhan Singgih Zein Massaid , Murtono
Published: June 2024

The module is a teaching material that is packaged practically and systematically so that it can be accessed independently by both teachers and students. E-modules are adaptations of learning modules to the current digital era, so that in operation e-modules utilize technology, both computers and cellphones. This study aims to 1) produce multi-representation-based physics e-modules on momentum and impulse material that can be used in learning, 2) determine student responses related to multi-representation-based physics e-modules that have been produced, and 3) determine the quality of physics-based e-modules multi representation that will be used in classroom learning. This research belongs to R&D (Research and Development) research with the 4D Thiagarajan development model consisting of Defining, designing, Development, and Disseminating. This research is limited to the Development stage, to be precise, in extensive trials. The instruments used in this study included validation sheets, assessment sheets, and student response questionnaires. E-Modules are validated by material experts and media experts. The validation sheet in this study uses Aiken's V scale with three scales. In comparison, the e-module quality assessment was conducted by two material experts, two media experts, and two physics teachers. The e-module quality assessment sheet uses a Likert scale with four scales. The e-module trials in this study were divided into two stages: limited and extensive. Limited trials were conducted on ten students, while comprehensive trials were conducted on 36 students. Student response questionnaires used the Guttman scale with two scales: "agree" and "disagree" statements. The results of this study include: 1) multirepresentation-based physics e-modules on the subject of momentum and impulse have been produced to facilitate students' learning styles; 2) the quality of the e-module that has been developed based on material experts, media experts, and teachers has a successive average score of 3.29 in the very good category; 3.66 with very good category; and 3.74 with very good category; 3) The response of students to the e-module in limited trials and wide trials has a successive average score of 1.00 with the agreed category; and 0.95 with the agreed category.
Differential hemodynamic adaptations to tilt test in patients with idiopathic atrial fibrillation
Authors: Magajevski Adriano Senter , Távora‐Mehta Maria Zildany P. , Mehta Niraj , Maluf Débora L. Smith , Silva Edvaldo C. Pinheiro , Concato Leticia , Ortiz Marcio Rogerio , Doubrawa Eduardo , Lofrano‐Alves Marco Stephan
Published: June 2024

The hemodynamic response during the transition from the supine to standing position in idiopathic atrial fibrillation (AF) patients is not completely understood. This study aimed to analyze the hemodynamic changes that occur during the head‐up tilt test in idiopathic AF patients. We investigated the hemodynamic changes during the head‐up tilt test with impedance cardiography in 40 AF patients (12 with AF rhythm‐AFr and 28 with sinus rhythm‐AFsr) and 38 non‐AF controls. Patients with AFr had attenuated SVI decrease after standing when compared to AFsr and non‐AF [ΔSVI in mL/m2: −1.3 (−3.4 to 1.7) vs. −6.4 (−17.3 to −0.1) vs. −11.8 (−18.7 to −8.0), respectively; p < 0.001]. PVRI decreased in AFr but increased in AFsr and non‐AF [ΔPVRI in dyne.seg.m2/cm5: −477 (−1148 to 82.5) vs. 131 (−525 to 887) vs. 357 (−29 to 681), respectively; p < 0.01]. Similarly, compared with non‐AF patients, AFr patients also had a greater HR and greater CI increase after standing. The haemodynamic response to orthostatic challenge suggests differential adaptations between patients with AF rhythm and those reverted to sinus rhythm or healthy controls. Characterizing the hemodynamic phenotype may be relevant for the individualized treatment of AF patients.
Hybrid classical-Bayesian approach to sample size determination for two-arm superiority clinical trials
Authors: Sambucini Valeria
Published: June 2024

Traditional methods for Sample Size Determination (SSD) based on power analysis exploit relevant fixed values or preliminary estimates for the unknown parameters. A hybrid classical-Bayesian approach can be used to formally incorporate information or model uncertainty on unknown quantities by using prior distributions according to the Bayesian approach, while still analysing the data in a frequentist framework. In this paper, we propose a hybrid procedure for SSD in two-arm superiority trials, that takes into account the different role played by the unknown parameters involved in the statistical power. Thus, different prior distributions are used to formalize design expectations and to model information or uncertainty on preliminary estimates involved at the analysis stage. To illustrate the method, we consider binary data and derive the proposed hybrid criteria using three possible parameters of interest, i.e. the difference between proportions of successes, the logarithm of the relative risk and the logarithm of the odds ratio. Numerical examples taken from the literature are presented to show how to implement the proposed procedure.
Correlation of single-fiber electromyography studies and functional status in patients with amyotrophic lateral sclerosis
Authors: Rostás Róbert , Fekete István , Horváth László , Márton Sándor , Fekete Klára
Published: June 2024

Objective

Our aim was to examine the significance of single-fiber electromyography (SFEMG) in patients diagnosed with amyotrophic lateral sclerosis (ALS) and determine the best correlating parameter with SFEMG parameters and clinical scales across different muscles including facial muscles.

Methods

SFEMG examinations were conducted on the extensor digitorum (ED), frontalis, and orbicularis oculi muscles. Mean jitter, percentage of increased jitter, fiber density (FD), and impulse blocking percentage were compared to reference values and functional scales.

Results

Significant differences (p < 0.001) were observed between the patients’ SFEMG results and reference values in all muscles. Significant correlations were found between SFEMG parameters and clinical scales, particularly when considering both FD and jitter. A notable value of the ALS Functional Rating Scale Revised (ALSFRS-R) was detected in all muscles: 31 points in the ED muscle, 30 in the orbicularis oculi muscle, and 31 in the frontalis muscle. Below this ALSFRS-R threshold, the percentage of increased jitter was higher, while FD remained relatively low.

Conclusion

SFEMG examination emerges as a valuable tool for better understanding ALS and holds potential for assessing prognosis. Combined jitter and FD analysis showed the strongest correlation with clinical scales. In addition to the ED muscle, the orbicularis oculi muscle may be important in the assessment.
Comparative study of couple stress fluid flow using OHAM and NIM
Authors: Farooq Muhammad , Nawaz Rashid , Khan Alamgeer , Younis Bakri Adam , DawAlbait Fathi Mohammed , Ismail Gamal M.
Published: June 2024

In this article, the plane Poiseuille flow of couple stress fluid of Vogel’s model between two parallel plates under the influence of non-isothermal effects have been investigated using Optimal homotopy asymptotic method (OHAM) and New iterative method (NIM). The governing continuity and momentum equations are transformed to ordinary differential equations and the coupled system of differential equations is then explored using the said methods. The expressions for velocity profile, temperature distribution, average velocity, volume flux, and shear stress have been obtained employing the said methods. Various essential flow properties have been presented and discussed. The results acquired via these techniques are in the form of infinite series; thus, the results can be effortlessly calculated. Comparison of both techniques are illustrated with the help of different tables and graphs and found both methods to be in a good agreement. Consequently, it will be more appealing for the investigators to apply the proposed methods to diverse problems arising in fluid dynamics.
Assessment of the landscape identity through participation in the framework of a landscape character research
Authors: Csorba Péter , Jombach Sándor , Boromisza Zsombor , Túri Zoltán , Bánóczki Krisztina , Konkoly-Gyuró Éva
Published: June 2024

The physical and emotional character of the landscape is an increasingly important ecosystem service factor in Hungary, too, and the strong identity of residents with the landscape is part of their well-being. Between 2016 and 2022, we prepared the landscape character map of the entire country. One of the essential elements of the project was that in four study areas – Sopron–Lake Fertő region (containing Sopron Mountains and Basin together with Lake Fertő), Gerecse Mountains, Tápió-vidék region and Tiszazug region – as landscape units, we tried to reveal the feelings of the residents related to the landscape using different methods. One of the most effective tools was surveys organised in workshops (personal or online) when we inquired about how the residents see landscape patterns, land use, and the changes in the surroundings of their settlements. One of the most important lessons learned from the study areas was that the local citizens usually have an indisposition for large-scale alterations of the accustomed environment, which leads to less familiar feelings and weakens the near natural character of the landscape. The results were compared with international experience.
Suburban neighbourhoods versus panel housing estates – An ecological footprint-based assessment of different residential areas in Budapest, seeking for improvement opportunities
Authors: Egedy Tamás , Szigeti Cecília , Harangozó Gábor
Published: June 2024

In this study, the household consumption-related ecological footprint of lifestyles linked to panel housing estates and suburban neighbourhoods were compared in the case of Budapest and its suburbs. Our results show that the biggest parts of the ecological footprint are in both study areas the carbon, the cropland and the forest components, in line with earlier calculations. On the whole, the ecological footprint values are bigger in the suburban study area (2.63 gha/capita) compared to the panel housing estates (2.29 gha/capita), mainly because of the differences between the carbon uptake and the built-up land components. Beyond comparing the ecological footprint values of different residential areas, the study also contributes to the literature by addressing the improvement options of the respective areas through a rough model calculation on the reduction opportunities in both cases, resulting 36 percent in case of panel housing estates, and 47 percent in the suburban areas. Although these values have to be considered cautiously, they show significant opportunities in ecological footprint reduction in both types of residential areas supported by individual motivations, as well as by policy measures.