bluuebunny/crossref_metadata_2025 huggingface dataset:
Herbs and their Bioactive Compound’s Role in the Management of Rheumatoid Arthritis and Related Inflammatory Conditions
Authors: Bharati Abinash Chand , Singh Seema , Singh Sandeep Kumar , Gautam Pavan Kumar , Kumar Ajay
Published: July 2024

Arthritis is the medical term for swelling or inflammation of one or more
joints, ligaments, and surrounding tissues. Rheumatoid arthritis (RA) is an
inflammatory autoimmune arthritis that is one of the 100 forms of arthritis. Currently,
this autoimmune inflammatory arthritis is incurable. Still, treatment is done on an
individual basis of symptoms with the primary goal of minimising joint discomfort and
inflammation, improving joint performance, and preventing cartilage damage and
distortion. Pharmacotherapy of Rheumatoid arthritis includes nonsteroidal antiinflammatory drugs (paracetamol, naproxen sodium, ketoprofen, diclofenac), biological
agents (rituximab, adalimumab, tocilizumab), and disease-modifying anti-rheumatic
drugs (penicillamine, sulfasalazine, gold), immunosuppressants (methotrexate,
cyclophosphamide), and corticosteroids (prednisolone and methylprednisolone) along
with physical therapy. The inability to achieve complete remission from chronic
diseases, as well as the expensive cost of new treatments, and the long-term side effects
and risks of modern medicine, have all contributed to a rise in public interest in
alternative medicine in recent years and different approaches to treating arthritis are
continually being researched. Dietary changes, nutritional supplements, and the use of
botanicals and phytochemicals are some of the more popular alternative treatment
options for RA. Dietary phenolic compounds, terpenoids, saponins, flavonoids,
carotenoids, and alkaloids have effectively slowed the progression of arthritic disease
because of their ability to alter pro-oxidant and pro-inflammatory pathways. In addition
to whole herbs and spices and their extract, many isolated phytoconstituents have been
discovered to have healing capability in the treatment of rheumatoid arthritis. These
compounds include aconite, brucine, kaempferol, tamaractam, andrographolide,
artemisinin, asiaticoside A, bufalin, hecogenin, curcumin, swertiamarin, resveratrol, cardamonin celastrol, lapachol, brazilin, thymoquinone, asperosaponin VI, liquiritin, βelemene, oleanolic acid acetate, ellipticine, hesperidin, and sinomenime. The current
review outlines the role of medicinal plants, herbs, dietary supplements, and isolated
bioactive compounds from plants in the treatment and management of rheumatoid
arthritis, as well as their mechanism of pharmacological action.
Future of Nanotechnology-Based Drug Discovery
Authors: Weerasinghe Laksiri , Munaweera Imalka , Kumarage Senuri
Published: July 2024

By enhancing drug administration and diagnostics, nanotechnology is
transforming the healthcare industry. Novel approaches to drug design are being driven
by combining cutting-edge technologies such as nanorobots and artificial intelligence.
Healthcare can benefit from the potential of nanotechnology through the development
of multifunctional nanotherapeutics, which could close gaps in the current therapeutic
field.

Powered by integrated circuits, sensors, and data storage, nanorobots can increase
efficiency and lessen systemic effects while follow-up care for cancer patients is made
simpler by nanosensors. Additionally, nanotherapeutics have gained their way in
developing novel therapeutics to overcome cancer drug resistance by targeting the
mechanisms that induce the drug resistance. Another upcoming field in nanomedicine
is the utilization of 3D printing techniques in order to create solid dosage forms based
on nanomedicine. By enabling flexible design and on-demand manufacture of
customized dosages, enhancing bioavailability, and other attributes, 3D printing
technology has revolutionized the pharmaceutical industry. The futuristic applications
of nanotechnology hybridized with novel techniques will be discussed in this chapter. 
Thoracotomy: An Overview of Perioperative Anaesthetic Management
Authors: Solanki Nilesh Maganbhai ,   Department of Anesthesia, B. J. Medical College Civil Hospital Ahmedabad, Gujarat India, Engineer Smita , Shah Namrata , Mistry Nirmal , Tamilanban Soundarya ,   Department of Anesthesia, B. J. Medical College Civil Hospital Ahmedabad, Gujarat India,   Department of Anesthesia, B. J. Medical College Civil Hospital Ahmedabad, Gujarat India,   Department of Anesthesia, B. J. Medical College Civil Hospital Ahmedabad, Gujarat India,   Department of Anesthesia, B. J. Medical College Civil Hospital Ahmedabad, Gujarat India
Published: July 2024

Background: The anesthesiologist's role during open thoracotomy includes using a double lumen tube (DLT) for lung isolation, maintaining oxygenation with one-lung ventilation (OLV), and providing postoperative analgesia. This study aims to describe patient demographics, comorbidities, perioperative anesthetic management, complications, and the effectiveness of epidural catheter analgesia. Methods: In this prospective, observational study, patients who underwent open thoracotomy for decortications were evaluated. Thoracotomy was done under general anaesthesia, OLV with DLT, and epidural analgesia. Postoperatively, all the patients were shifted to the intensive care unit. Collected data included patient demographics, associated co-morbidities, severity of lung diseases, complications, and postoperative recovery. Postoperative analgesia was assessed by the visual analogue scale (0-10). Result: Of 20 patients, 16 were male, and 4 were female, with a mean age of 35 years (range 15-60) and a mean weight of 52 kg (range 36-66). History of hypertension (N=5), hypertension with diabetes (N=3), obstructive lung disease (N=6), restrictive lung disease (N=11), and both combined (N=3) were noted on pre-anesthetic check-ups. Intraoperative complications were hypotension (N=3), desaturation (N=3), respiratory acidosis (N =7), and metabolic acidosis (N=3). Postoperative analgesia was managed with an epidural catheter (N=18) & systemic analgesia (N=2). All patients had uneventful postoperative courses except one patient who had pulmonary edema and did not survive. Conclusion: Patients undergoing open thoracotomy had an increased risk for adverse perioperative outcomes. The incidences of perioperative morbidity are high in patients with associated comorbidities. Proper OLV strategy helps to correct intraoperative desaturation. Epidural analgesia plays a key role in postoperative recovery.
PEMBELAJARAN BERDIFERENSIASI SEBAGAI PENDEKATAN KERAGAMAN PESERTA DIDIK UNTUK MEMENUHI TARGET KURIKULUM
Authors: Wardani Kirana ,   Universitas Negeri Malang, Darmawan Puguh
Published: July 2024

The purpose of this study is to gather information and clarify concepts related to differentiated learning to meet curriculum goals based on student diversity. Differentiated learning is learning that helps the student's learning process according to the students' learning profile, learning readiness and interests. The method used in this article is a library approach that collects information from documents, books, articles, scientific journals, and literature related to differentiated learning as an approach to student diversity to meet curriculum targets. After analyzing various trusted sources, researchers can produce conclusions which is valid and useful. Conclusion Students have diversity in each individual such as interests, readiness, learning profiles. This requires a curriculum and learning that can facilitate the needs and character of students, one of which is an independent curriculum and differentiated learning. Differentiation learning consists of three aspects, namely content differentiation, product differentiation and process differentiation
IMPLEMENTASI GERAKAN LITERASI SEKOLAH MELALUI POJOK BACA SEBAGAI PENINGKATAN MINAT BACA SISWA SD
Authors: Vega Diva Nadia ,   Universitas Negeri Malang, Utama Candra
Published: July 2024

Efforts continue to increase students' interest in reading, the government has launched the School Literacy Movement (GLS). GLS does not only focus on reading activities, but also includes writing, listening and listening. In elementary school, students need good reading skills so that they can become the next generation of a literate nation. Students' low interest in reading is an important reason to fix literacy problems. This research analyzes the implementation of reading corners to increase students' interest in reading as one of the goals of the school literacy movement. Data collection was obtained through qualitative research methods using a descriptive approach using observation and unstructured interview techniques. From the results of this research, it was found that the use of reading corners still did not arouse students' interest in the reading literacy of students at SDN 04 Duwet.
KONSEP NITU DALAM KEPERCAYAAN MASYARAKAT DUSUN LEWOURAN
Authors: Muda Stefanus Dama ,   Universitas Teknologi Yogyakarta, Muda Florianus Pruda
Published: July 2024

This article explores the concept of nitu (spirit) in the beliefs of the Lewouran village community, located in Lewotobi Subdistrict, East Flores Regency, East Nusa Tenggara. Specifically, it delves into the concept of nitu in the traditional beliefs of the Lewouran community. The objective of this article is to elucidate whether nitu indeed possesses distinct powers in the lives of the Lewouran villagers. The research employs a qualitative descriptive methodology, combining field research and literature review methods. The findings of this study suggest that nitu, especially nitu date (malevolent spirit), are not merely individual or collective spiritual entities with specific supernatural abilities. Instead, they can have a significant impact on human life, leading to illnesses, diseases, and various calamities within the community.
UNRAVELING THE REALITY OF RELIGIOUS FREEDOM
Authors: Saraswati Destriana ,   Universitas Brawijaya
Published: July 2024

UNRAVELING THE REALITY OF RELIGIOUS FREEDOM
GENDER-SENSITIVE FAMILY RESILIENCE EDUCATION AS A PREFERRED ACTION AMIDST THE DIVORCE TREND IN INDONESIA
Authors: Zuhriah Erfaniah ,   UIN Maulana Malik Ibrahim, Fuadi Suud , Sukadi Imam , Ashari Zahrah Salsabillah ,   UIN Maulana Malik Ibrahim,   UIN Maulana Malik Ibrahim
Published: July 2024

Gender often becomes an issue in assuming roles in family resilience. Some people believe that maintaining household stability is a responsibility solely entrusted to the husband. However, one of the factors contributing to divorce is the imbalance in household stability resulting from the lack of roles among family members in maintaining family resilience and well-being. This study aims to explore how family resilience education operates in Kemantren Village, Malang Regency. Simultaneously, this article also seeks to examine the implications of gender perspectives on the community in Kemantren Village. The research method used is qualitative, with a sociological approach. This study involves 27 individuals as informants who will fill out questionnaires and also serve as interview subjects to understand the state of family resilience education in Kemantren Village. The study findings indicate that women's roles in the family not only influence overall family dynamics but can also be crucial factors in facing challenges and strengthening family resilience. The insights from family resilience education in Kemantren Village have had a positive impact on the sustainability of their households. Considering women's roles in the context of family resilience is one essential step in addressing the divorce trend in Indonesia.
Wacana Perempuan Di Koran De Expres Tahun 1912-1914 Dari Aspek Berita Nasional, Internasional, Dan Sastra
Authors: Rooyackers Max
Published: July 2024

Penelitian ini memperdalami bagaimana wacana emansipasi perempuan terwujud dalam surat kabar De Expres yang diredaksi oleh E.F.E. Douwes Dekker dan H.C. Kakebeeke. Tiga aspek diperhatikan dalam keseluruhan wacana perempuan, yaitu berita lokal dan nasional, internasional, serta sastra. Masing-masing aspek memiliki peran tersendiri dalam membentuk wacana perempuan. Berita nasional menawarkan esai kritis dalam konteks lokal, sedangkan berita internasional menawarkan esai kritis dalam konteks yang berbeda. Sastra juga menawarkan konteks lokal, namun dalam bentuk yang lebih ringan dan santai. Meskipun ciri-cirinya berbeda, terdapat hubunga antara ketiga aspek dalam membangun wacana perempuan yang kokoh dan konsisten. Berita dan sastra tidak secara acak digunakan, melainkan dengan tujuan menyampaikan gagasan. Emansipasi perempuan diperjuangkan melalui meningkatkan kedudukan perempuan dalam bidang ekonomi, sosial, dan politik. Emansipasi ini harus disesuaikan dengan latar belakang budaya perempuan, baik mereka Eropa, Indo-Eropa, atau Nusantara. Beberapa anggota redaksi seperti Tjipto Mangoenkoesoemo menulis esai kritis untuk menyampaikan itu, sedangkan Douwes Dekker menggunakan komentar terhadap peristiwa di seluruh dunia dan sastra. Penelitian historis mengenai wacana perempuan pada umumnya hanya memperhatikan aspek berita nasional tanpa memperhatikan aspek berita internasional dan sastra. Penelitian ini menggunakan metode kualitatif dengan pendekatan sejarah Kuntowijoyo untuk mengungkapkan proses dan wujud pembentukan wacana perempuan yang progresif pada zamannya.
FORMACIÓN DE DOCENTES DE BÁSICA PRIMARIA EN LA CREACIÓN DE RECURSOS EDUCATIVOS DIGITALES: INTEGRANDO LAS TIC A TRAVÉS DEL DISEÑO DE PRESENTACIONES ANIMADAS
Authors: Jerónimo Montiel Tatiana , Torres Ortega Mara Sofia , Lee Linda Luz
Published: July 2024

La integración efectiva de la tecnología en el proceso educativo es fundamental para mejorar la calidad de la enseñanza. Sin embargo, muchos docentes enfrentan desafíos al intentar adoptar tecnologías educativas debido a la falta de conocimientos especializados. La investigación llevada a cabo para mitigar esta problemática, tuvo como objetivo fortalecer los procesos de enseñanza aprendizaje al promover la integración de las Tecnologías de la Información y Comunicación (TIC) en el contexto educativo mediante la implementación de una estrategia de formación para el desarrollo de recursos educativos digitales, específicamente presentaciones animadas, dirigido a los docentes de básica primaria de la institución educativa Camilo Torres sede Mi Amiguito en Montería, Colombia, quiénes manifestaron estas necesidades de formación. Los resultados obtenidos demostraron que la formación de los docentes en la creación de recursos educativos digitales contribuye a la mejora de la calidad educativa. Los recursos diseñados por los propios maestros se adaptan mejor a las necesidades específicas de los estudiantes, lo que conduce a un aprendizaje significativo y relevante. Además, los docentes participantes en el estudio adquirieron las habilidades tecnológicas necesarias para continuar el con proceso de diseño de recursos que promuevan un proceso de enseñanza, aprendizaje más efectivo y dinámico. La investigación subraya la necesidad de ofrecer programas de formación docente especializados en la creación de recursos educativos digitales, así como de promover una cultura de actualización. De esta manera, se puede avanzar hacia una educación de calidad que prepare a los estudiantes para enfrentar los desafíos del siglo XXI.
Effectiveness of self-care monitoring on self-behavior of diabetes mellitus patients
Authors: Suciana Fitri , Budi Syahputri Rezyana , Winarti Ambar , Pramono Cahyo
Published: July 2024

Background : Diabetes Mellitus is called the silent killer because this disease can affect all organs of the body and cause various kinds of complaints. Chronic hyperglicemia can affect the sufferes’s quality of life and cause rehospitalization. Decreased quality of life is caused emergence of hyperglicemia complications.. Controlling diabetes mellitus includes monitoring blood sugar levels, exercise or physical activity, diet, education and drug of diabetes mellitus.

Diabetes mellitus is a metabolic disease that causes complications. The problem of complications is prevented by performing the 4 pillars of self-care while at home.

Objectives : The purpose of this research is to determine the effectiveness of DM management on self-care.

Methods : The research design in this study used a quantitative descriptive quasi-experimental method . The sampling technique used accidental sampling with a total of 30 respondents. Data analysis used the Wilcoxon test to determine pre and post results in each group and used the Mann Whitney test to determine the mean difference in the two groups.

Inclusion criteria included respondents who were registered as prolanis members. The research instrument used a self-care monitoring sheet with the SDSCA (Summary of Diabetes Self-Care Activity) questionnaire with  r table value 0.361

Results : The result is the Asymp.Sig value. (2 tailed) has a value of 0.001, so Ha is accepted, which means there is a difference in self-care ability between before being given DM management and after being given DM management.

Based on the findings of researchers in this study, the value of Asymp.Sig. (2-tailed) value is 0.001, meaning that Ha is accepted. there is a difference between pretest and posttest in both the control and intervention groups.

Conclusions : There is a difference in the average self care ability of diabetes mellitus patients using monitoring sheets.

The conclusion is that the self-care management programme is effective on self-behavior.

 
Digital Interventions for Reducing Loneliness and Depression in Korean College Students: Mixed Methods Evaluation
Authors: Kang Boyoung , Hong Munpyo
Published: July 2024

Background

The COVID-19 pandemic has exacerbated the prevalence of loneliness and depression among college students. Digital interventions, such as Woebot (Woebot Health, Inc) and Happify (Twill Inc), have shown promise in alleviating these symptoms.

Objective

This study aims to investigate the effectiveness and acceptability of Woebot and Happify in reducing loneliness and depression among college students after the COVID-19 pandemic.

Methods

A mixed methods approach was used over 4 months. A total of 63 participants aged 18 to 27 years from Sungkyunkwan University in Seoul, South Korea, were initially recruited, with an inclusion criterion of University of California, Los Angeles (UCLA) Loneliness Scale score ≥34. The final sample consisted of 27 participants due to attrition. Participants were randomly assigned to Woebot (15/27, 55%); Happify (9/27, 33%); or a control group using Bondee (Metadream), a metaverse social network messenger app (3/27, 11%). Quantitative measures (UCLA Loneliness Scale and Patient Health Questionnaire-9) and qualitative assessments (user feedback and focused interviews) were used.

Results

Although mean decreases in loneliness and depression were observed in the control and intervention groups after the intervention, the differences between the control and intervention groups were not statistically significant (UCLA Loneliness: P=.67; Patient Health Questionnaire-9: P=.35). Qualitative data indicated user satisfaction, with suggestions for improved app effectiveness and personalization.

Conclusions

Despite limitations, this study highlights the potential of well-designed digital interventions in alleviating college students’ loneliness and depression. The findings contribute to the growing body of research on accessible digital mental health tools and underscore the importance of comprehensive support systems. Further research with larger and more diverse samples is needed to better understand the effectiveness and optimization of such interventions.

Trial Registration

Clinical Research Information Service KCT0009449; https://bit.ly/4d2e4Bu
A Novel mHealth App for Smokers Living With HIV Who Are Ambivalent About Quitting Smoking: Formative Research and Randomized Feasibility Study (Preprint)
Authors: McClure Jennifer B , Heffner Jaimee L , Krakauer Chloe , Mun Sophia , Catz Sheryl L
Published: July 2024

BACKGROUND

More people who smoke and are living with HIV now die from tobacco-related diseases than HIV itself. Most people are ambivalent about quitting smoking and want to quit someday but not yet. Scalable, effective interventions are needed to motivate and support smoking cessation among people ambivalent about quitting smoking (PAQS) who are living with HIV.

OBJECTIVE

This study aims to develop an app-based intervention for PAQS who are living with HIV and assess its feasibility, acceptability, and potential impact. Results of this study will inform plans for future research and development.

METHODS

In phase 1, PAQS living with HIV (n=8) participated in user-centered design interviews to inform the final intervention app design and recruitment plan for a subsequent randomized pilot study. In phase 2, PAQS living with HIV were randomized to either a standard care control app or a similar experimental app with additional content tailored for PAQS and those with HIV. Participants were followed for 3 months. Feasibility focused on recruitment, retention, and participants’ willingness to install the app. The study was not powered for statistical significance. Indices of acceptability (satisfaction and use) and impact (smoking behavior change and treatment uptake) were assessed via automated data and self-report among those who installed and used the app (n=19).

RESULTS

Recruitment for both study phases was a challenge, particularly via web-based and social media platforms. Enrollment success was greater among people living with HIV recruited from a health care provider and research registry. Once enrolled, retention for the phase 2 randomized study was good; 74% (14/19) of the participants completed the 3-month follow-up. Phase 1 findings suggested that PAQS living with HIV were receptive to using an app-based intervention to help them decide whether, when, and how to stop smoking, despite not being ready to quit smoking. Phase 2 findings further supported this conclusion based on feedback from people who agreed to use an app, but group differences were observed. Indices of acceptability favored the experimental arm, including a descriptively higher mean number of sessions and utilization badges. Similarly, indices of potential impact were descriptively higher in the experimental arm (proportion reducing smoking, making a quit attempt, or calling free tobacco quitline). No participants in either arm quit smoking at the 3-month follow-up.

CONCLUSIONS

On the basis of this formative work, PAQS living with HIV may be receptive to using a mobile health–based app intervention to help them decide whether, when, or how to stop using tobacco. Indices of acceptability and impact indicate that additional research and development are warranted.

CLINICALTRIAL

ClinicalTrials.gov NCT05339659; https://clinicaltrials.gov/study/NCT05339659
Systematic Identification of Caregivers of Patients Living with Dementia in the Electronic Health Record: Known Contacts and Natural Language Processing (Preprint)
Authors: Martin Daniel , Lyons Jason , Powers J David , Daddato Andrea E , Boxer Rebecca S , Bayliss Elizabeth , Portz Jennifer D
Published: July 2024

BACKGROUND

Systemically identifying caregivers in the electronic health record (EHR) is a critical step for delivering patient-centered care, enhancing care coordination, and advancing research and population health efforts in caregiving. Despite EHRs being effective in identifying patients through standardized data fields like demographics, lab results, medications, and diagnoses, identifying caregivers through the EHR is challenging in the absence of specific caregiver fields.

OBJECTIVE

Recognizing the complexity of identifying caregiving networks of people living with dementia (PLWD), this study aimed to systematically capture caregiver information by combining EHR structured fields and unstructured notes and free text.

METHODS

Among a cohort of PLWD aged ≥60 from Kaiser Permanente Colorado (KPCO) caregiver names were identified by combining structured patient contact fields, i.e. known contacts, with name-matching and natural language processing (NLP) techniques of unstructured notes and patient portal messages containing caregiver terms.

RESULTS

Among the cohort of N=789 PLWD, 95% had at least one caregiver name listed in structured fields (mean=2.1). Over 95% of the cohort had caregiver terms mentioned near a known contact name in unstructured encounter notes, with 35% having a full name match in unstructured patient portal messages. The NLP model identified 7,556 “new” names in the unstructured EHR text containing caregiver terms among 99% of the cohort with high accuracy and reliability (F1=.85, precision=.89, recall=.82). 87% of the cohort had a new name identified ≥2 near a caregiver term in their notes and portal messages.

CONCLUSIONS

Analysis revealed significant patterns in caregiver-related information distributed across structured and unstructured EHR fields, emphasizing the importance of integrating both data sources for a comprehensive understanding of caregiving networks. A framework was developed to systematically identify potential caregivers across caregiving networks using structured and unstructured EHR data. This approach has the potential to improve health services for PLWD and their caregivers.
Restoring Sentiments: Understanding Citizens’ Response to Social Activities on Twitter in U.S. Metropolises During the COVID-19 Pandemic Using Fine-tuned Large Language Model (Preprint)
Authors: Saito Ryuichi , Tsugawa Sho
Published: July 2024

BACKGROUND

The COVID-19 pandemic remains significant in the collective memory in 2024. As of March 2024, over 676 million cases, 6 million deaths, and 13 billion vaccine doses have been reported. It’s crucial to evaluate sociopsychological impacts as well as public health indicators such as these to understand the pandemic’s effects.

OBJECTIVE

This paper explores the sentiments of residents of major U.S. cities toward restrictions on social activities in 2022 during the transitional phase of the COVID-19 pandemic, from the peak of the pandemic to its gradual decline. By illuminating people’s susceptibility to COVID-19, we provide insights into the general sentiment trends during the recovery phase of the pandemic.

METHODS

To analyze these trends, we collected posts (N = 119,437) on the social media platform Twitter (now X) made by people living in New York City, Los Angeles, and Chicago, which were impacted by the COVID-19 pandemic in similar ways. Additionally, we constructed a sentiment estimation model by fine-tuning a large language model on the collected data and used it to analyze citizens’ sentiments as the pandemic changed.

RESULTS

In the evaluation of models, GPT-3.5 Turbo with fine-tuning outperformed GPT-3.5 Turbo without fine-tuning and RoBERTa-Large with fine-tuning, demonstrating significant accuracy (0.80) and F1 score (0.79). The findings using GPT-3.5 Turbo with fine-tuning reveal a significant relationship between sentiment levels and actual cases in all three cities. Specifically, the correlation coefficient for New York City is 0.89, for Los Angeles is 0.39, and for Chicago is 0.65. Furthermore, feature words analysis shows that coronavirus-related keywords were replaced with non-coronavirus-related keywords in New York City and Los Angeles from January 2022 onwards and Chicago from March 2022 onwards.

CONCLUSIONS

The results show a gradual decline in sentiment and interest in restrictions across all three cities as the pan-demic approached its conclusion. These results are also ensured by a sentiment estimation model fine-tuned on actual Twitter posts. This study represents the first attempt from a macro perspective to depict sentiment using a classification model created with actual data from the period when COVID-19 was prevalent. This approach can be applied to the spread of other infectious diseases by adjusting search keywords for observational data.
Development, reliability, and validity assessment of a numerical algorithm to detect centralization phenomenon and directional preference among spinal pain patients. (Preprint)
Authors: Deneuville Jean-Philippe , Billot Maxime , Lebrault Victor , Ounajim Amine , Cervantes Alexandra , Goudman Lisa , Moens Marteen , Roulaud Manuel , Guiraud Matthieu , Nivole Kevin , David Romain , Rigoard Philippe
Published: July 2024

BACKGROUND

Affecting millions of people, spinal pain is the leading cause of years lived with disability worldwide since the nineties. Centralization phenomenon (CP) and directional preference (DP) are common features in spinal pain patients, indicating a good clinical prognosis. CP is defined as a rapid and lasting migration of distal pain from the limb to the center of the spine after repeated movement tests. DP is a broader concept in which both the migration and decrease of pain are considered. While their detection has still been based on clinician decision, digital tool would provide objective measurements.

OBJECTIVE

We developed and assessed the reliability and validity of a new algorithm to detect CP and DP among spinal pain patients using quantitative a pain mapping software (PRISMAP).

METHODS

We designed a two-phase retrospective, cross-sectional, double-blinded diagnostic accuracy study. In Phase 1, using PRISMAP, we recorded and analyzed pain variations before and after a CP-focused physiotherapy session with specialized physiotherapy (PT). PTs classified patients as CP+ or CP-. We developed an algorithm to model changes in pain topography and intensity, identifying patients relative to PT classification. In Phase 2, PTs conducted four pain mappings. The initial two maps depicted a three-day overall patient pain profile, from which reliability and agreement were calculated using Intraclass Coefficient Correlation (ICC), Standard Error of Measurement (SEM), Coefficient of Variation (CV), and Bland-Altman analysis (BA). PTs then documented t-time pain mapping pre- and post-repeated movement test, classifying patients into CP-/CP+ and DP-/DP+. Validity parameters (sensitivity, specificity, positive and negative likelihood ratios (LR+/LR-)) were calculated from the latter two maps, using PT classification as the standard reference.

RESULTS

Twelve patients were included in Phase 1 and 49 in Phase 2. The algorithm demonstrated good reliability (ICC=0.993 [95%CI 0.988–0.996], SEM=0.211, CV=12.2%, and bias error with the BA of -0.041 representing 2.4% of the sample mean). Validity for CP was 92.0% [95%CI 73.7–99.02], 79.2% [95%CI 57.8–92.9], 4.42 [95%CI 2.01–9.71], 0.1 [95%CI 0.03–0.39] for sensitivity, specificity, LR+, and LR-. Validity for DP was 81.3% [95%CI 63.56–92.79], 88.2% [95%CI 63.6–98.5], 6.91 [1.86–25.66], and 0.21 [95%CI 0.1–0.45] for sensitivity, specificity, LR+, and LR-.

CONCLUSIONS

The mathematical modeling of CP and DP is reliable and valid. This approach may enhance patient selection for future studies and serve as a clinical aid for practitioners.
Kampung Durian Pranan Agritourism Initiatives: An Analysis of Actor Dynamics
Authors: Yulianti Hetri , Mulyasari Runavia , Sushartami Wiwik
Published: July 2024

Developing agritourism is a useful strategy to enhance the value of the local agriculture industry. Agritourism utilises agricultural products and activities to attract tourists to rural areas. As an early stage of agritourism development, land conversion has become a supporter of attempts to create agritourism attractions. The notion of locality exists to distinguish and identify the tourism attraction area. This research focuses on durian agritourism in Padukuhan Pranan, Banjaroya Village, Kalibawang, Kulon Progo Regency, Special Region of Jogjakarta. Special attention is made to the dynamics of the local actors. Data collection was carried out using ethnographic methods through observation and in-depth interviews, for approximately three months (July-September 2023). The informants in this research were several actors involved in the development and management of Kampung Durian Pranan agritourism. The study discovered that converting the property to agritourism benefited Padukuhan Pranan by establishing the Kepranan durian as a symbol of local identity. With its central emphasis on the local populace, the Pranan Durian Village Festival serves as an outstanding instance of the substantial contributions made by community members. The collaborative efforts of local actors to effect positive change are exemplified through the festival’s design and execution, which are built upon their roles as initiators, motivators, and educators. However, it is worth noting that the reestablishment of a sustainable family farm as a means to regenerate agritourism’s sustainability has yet to transpire due to the continued dearth of interest among the younger generation in agritourism. Hence, agritourism planning needs to be designed by organising activities involving the younger generation and rebuilding family farms to create resilience and sustainability.
A Study on Influencing Factors of Audience Satisfaction with Online Concerts
Authors: Chen Zhiyuan
Published: July 2024

Affected by the COVID-19 epidemic at the end of 2019 and the advancement of technology, the number of audiences of online concert has experienced a surge. With the gradual recovery of offline concerts in past two years, online concerts have not vanished, but have attracted global audiences together with offline concerts. According to researches and surveys, there are multiple factors affecting online concerts’ audience satisfaction, not just one factor. This paper uses literature research, questionnaires and empirical analysis to investigate factors affecting online concerts’ audience satisfaction today, and then finds that there is a positive correlation, and finds that strengths of influencing from small to large are: adequacy of pre preparation for online concerts, additional services’ quality for online concerts, and quality of online concerts’ contents. It also finds that usage of live music in online concerts plays a positive moderating role in the relationship between quality of online concerts’ contents and online concerts’ audience satisfaction. At the end of this paper, some suggestions are provided for online concerts and their organizers in the conclusion part.
Practice the Technique of Singing Vietnamese Light Music Song for Middle-age Female Voices
Authors: Lam Do Thi
Published: July 2024

Classical chamber music vocal techniques, typically the bel canto singing style, have been shaped with many methodical methods. In our country, several famous vocal pedagogues have compiled and written books on teaching vocal music such as Nguyen Trung Kien and Ho Mo La. Unlike classical chamber singing, currently, in our country, there are no books or unified in-depth research on light music singing techniques. While classical vocal techniques require strictness and the singer must accurately perform every detail recorded in the song, light music is characterized by a fairly free and comfortable way of singing from the mouth, how to vibrate your voice, process sound to express your work... Singers can be creative from their point of view, as long as they create their mark and attract listeners.
Preserving Secondary Knowledge
Authors: Rechert Klaus , Gieschke Rafael
Published: July 2024

Emulation and migration are still our main tools for digital curation and preservation practice. Both strategies have been discussed extensively and have been demonstrated to be effective and applicable in various scenarios. Discussions have primarily centered on technical feasibility, workflow integration, and usability. However, there remains one important aspect when discussing these two techniques: managing and preserving operational knowledge. Both approaches require specialized knowledge but especially emulation requires future users to also have a great variety of knowledge about past software and computer systems for successful operation. We investigate how this knowledge can be stored and utilized, and to what extent it can be rendered machine-actionable, using modern large language models. We demonstrate a proof-of-concept implementation that operates an emulated software environment through natural language.
Study of Various Computer Vision Algorithms for Registration in Augmented Reality: A Survey
Authors: Sharma Sachin , Thakur Deepak , Singh DR. A J
Published: July 2024

Abstract: Augmented reality is defined as the fusion of virtual object in real world. Registration is basic step for creating an immersive AR experience to the user. The registration algorithms helps in placing the virtually created object in the most accurate position in the real world. This paper shows an in-depth comparative analysis of various registration algorithm under computer vision that are used for AR applications. The comparative analysis helps in identifying the strengths, weaknesses and the applicability of each algorithm in various AR fields by studying different case studies and real-world applications which helps in showing the practical implication of these algorithms. Also, the challenges associated with AR are discussed and future scope of this aims at advancement of the registration algorithms so as to make the AR experience more functionable and smooth. This survey paper can help researchers, developers who have interest in knowing or exploring the field of computer vision algorithms for solving the registration problem in Augmented Reality.
Stress and Burnout in the European Workplace and the Role of Resilience
Authors: Butz M. , Mrazova M. , Deaconu D. , Czirfusz A.
Published: July 2024

Objective: This thesis examines the link between stress, burnout and resilience in the European workplace. Design: review article Methods: Using a large number of studies and data sets from various European countries, the effects of stress in the workplace on individual health and performance as well as on a societal level are analyzed. Results: It becomes clear that stress and burnout are not just individual problems, but are also influenced by national economic, cultural and political factors. The results show that the risk of burnout can be influenced by a variety of different factors, which must be taken into account when developing countermeasures. In addition, cultural differences in coping with stress and the role of resilience as a protective factor against burnout are examined. Conclusion: The paper concludes that fostering resilience and supportive environments is crucial for mitigating workplace stress and preventing burnout.
Early Intervention in pediatric Dentistry: Nurturing lifelong Oral health Habits
Authors: Deaconu D. , Racek Ch. , Czirfusz A.
Published: July 2024

Early intervention in pediatric dentistry is crucial in influencing children’s oral health trajectory and establishing habits that may last a lifetime. Pediatric dentists strive to develop good dental hygiene habits in young children via early detection, treatment, education, and prevention (Happykidsdental, 2024). To foster good dental hygiene habits for life, this study explores the many aspects of early intervention in pediatric dentistry. Pediatric dentistry is essential for youngsters to have healthy teeth and gums. It considers the specific requirements and difficulties during infancy and goes beyond regular dental checkups (Wang, 2023). Pediatric dentists provide the groundwork for optimal dental health throughout a child’s life by concen trating on early intervention, individualized treatments, and preventative care (Krol and Whelan, 2022). They make the dentist’s office a fun place for kids, encouraging them to have good experiences there and teaching their parents how to care for their teeth better (Happykidsdental, 2024). Issues such as thumb-sucking, teething, and assisting youngsters with orthodontic troubles are also part of a pediatric dentist’s expertise (Lin, 2022). Pediatric dentists are medical professionals who focus on children’s oral and dental health (dentalcare.com, 2023). They help children maintain good teeth and jaw development, which benefits their general health. Pediatric dentistry is a subspecialty of general dentistry that focuses on the specific problems and requirements of dental health in children. It covers a lot of ground, from general dental checkups and education to more precise treatments for common problems in children and teenagers (Clinical Affairs Committee, 2012). Dental treatment for children goes beyond just fixing cavities; pediatric dentists also work to alleviate anxiety and promote a good attitude toward the dentist from a young age (Happykidsdental, 2024). Building a solid foundation for excellent dental health throughout a child’s life begins in the early years (Baker, Lee and Wright, 2019). The importance of early interventions in establishing excellent oral hygiene habits and avoiding dental disorders before they happen is acknowledged in this particular area (Krol and Whelan, 2022). Pediatric dentists play a dual role as healthcare practitioners and educators, helping children and their families maintain good oral health and wellness. The field of pediatric dentistry focuses on the dental health and welfare of children from the time they are infants until they reach puberty (Wang, 2023). Encouraging youngsters to form good habits with their teeth and gums is integral to this niche field’s mission to promote dental health (Lin, 2022). The formative years are essential to provide the groundwork for excellent dental health throughout a child’s life.
The implementation of the flipped classroom approach to improve the EFL students’ reading ability
Authors: Septiani Rahmah , Muluk Safrul , Habiburrahim Habiburrahim
Published: July 2024

Reading is a vital language skill that necessitates mastery for knowledge acquisition. However, the focus of students has shifted away from reading due to technological advancements. Despite this, the literacy levels of students in Indonesia are alarmingly low, ranking 74 out of 79 in the PISA Survey 2018. This study aimed to explore the integration of technology in educational settings. Specifically, by implementing a technology-based flipped classroom model, the researcher aimed to encourage and educate junior high school students on the constructive use of smartphones. The primary objective was to investigate whether the adoption of flipped classrooms, combined with technology utilization, could potentially enhance students' reading proficiency. To achieve this goal, an experimental research design was employed, comprising both an experimental group and a control group. Pre-tests and post-tests were conducted for both groups, with the experimental group receiving the flipped classroom intervention, while the control group experienced traditional classroom methods. The findings indicated that the experimental group exhibited superior performance compared to the control group.
The Study of Analysis Toward Zakat of Honey on Mazhab Imam Syafi’i Perspective
Authors: Harahap Haddad Ulum , Putra Dedisyah , Khalidi Muhadi , Linur Rahmat , Acela Nuriza
Published: July 2024

Honey is a special food ingredient because of its taste, nutritional value and high efficacy. That's why honey is revered by many people as a unique type of food that is also medicinal which has been known since ancient time because it is able to maintain the immune system for those who consume it. In the past, people were not familiar with honey livestock and only got it in forests, but now many people have cultivated honey and even developed it with a factory processed system in such a way. This research will discuss the position of honey and the law of zakat on the results of the honey business based on the thought of mazhab (school of thought concerning Muslim law) Imam Shafi'i. This research is a library research with a qualitative approach. The result of research was that Imam Syafi’I had two views known as Qaul al-Qadim and Qaul al-Jadid. Zakat of honey in qaul al-qadim is obligated to pay zakat with qiyas that honey included staple food based on hadist and prophet’s friends. Imam Syafi’I says that honey is not obligated to pay because it does not include staple food. Imam Syafi'i moved from qaul qadim to qaul Jadid because he found a stronger argument to be used as a legal basis. Therefore, Imam Syafi'i did ijtihad and dismantled the results of the previous ijtihad be based on weak arguments. He says “The hadith saḥiḥ is my mazhab and leave my opinion if it contradicts the hadith sahih”. Istinbath (method in understanding the proposition of revelation)of law used by him is Imam Syafi’I to construct the reason based the hadist. Keywords: Honey, Zakat, Imam Syafi’i
Indication of Istihsan Qiyas Khafi Al-Bazdawi in Contemporary Fatwa in Indonesia
Authors: Amir Amri , Siraj Firdaus , Bahar Muchlis , Wiza Rahmi , Salem Al-Saedy Ibrahim bin
Published: July 2024

This research aims to analyze Istihsan qiyas Khafi al-Bazdawi as indicated in contemporary fatwas in Indonesia. What is the concept of Istihsan qiyas khafi al-Bazdawi, and how is it relevant to contemporary fatwas in Indonesia? The research method used is descriptive analysis with a literature study approach sourced from journals, websites, books by al-Bazdawi and his lecturers. The results of the research show that Istihsan qiyas khafi al-Bazdawi is a process of intifa' (taking benefits) on a legal object by using qiyas/illat (legal reasons) khafi (hidden) by removing qiyas/illat jali (real reasons in law), and Istihsan Khafi al-Bazdawi's qiyas are considered relevant to a number of contemporary fatwas of the Indonesian Ulema Council (MUI), including: 1) the prosperity of cash waqf Sukuk, 2) the ease of Sukuk Mudharabah, Murabahah, Musyarakah, 3) the ease of Sweb when fasting, 4) the ease of Vaccine injection while fasting
The Conceptual Framework of International Law in the Historical Establishment of Islamic Law
Authors: Iffan Ahmad , Mujtahidin Syamsul , Algifari Muhammad Faiz
Published: July 2024

The legal enactment in the Makkah phase which lasted for approximately 13 years focused on cultivating the faith, strengthening its roots, and maintaining its purity. Islam makes the two sentences of the shahada as the realization of the aqidah as the door to a person's entry into the embrace of Islam which then applies Islamic laws to him. In efforts to adhere to the Islamic creed, it relies on logical arguments. The way to do this is by inviting humans to think about the universe, observing the signs of Allah's power and the beauty of His creation, and thinking about how all of this creation works in an orderly pattern. According to Sheikh Manna, the letters and verses that were included in the Makkah phase describe the orientation of faith by inviting humans to think and see the universe along with the heavens and the earth, witnessing the secrets that Allah keeps behind it all, and accuracy and perfection. in the universe itself, which is neatly arranged without any defects or doubts in it. Determination of Medina Law, The hijrah event was a separation between two societies in Islamic history. While in Mecca, the Islamic faith had been firmly ingrained in the souls of the Muhajirin and, like the Ansar, had taken the oath of allegiance. It was there that the seeds began to form which became the embryo of the founding of an Islamic society. Then they made Medina a place to settle in order to develop these seeds. "It is at this stage that da'wah begins to enter the stage of implementation in an organized manner," he said. Sheikh Manna said that the establishment of laws in Medina led to the formation of society and the establishment of rules in social matters. And the first step taken by Rasulullah SAW in building society was to bring brotherhood between the Muhajirin and the Ansar, whereby the Ansar people prioritized their brothers from among the Muhajirin over themselves.