bluuebunny/crossref_metadata_2025 huggingface dataset:
Multiwavelength Frequency Modulated CW Ladar: The Effect of Refractive Index
Authors: Barbieri Mariano , Pallotti Deborah , Siciliani de Cumis Mario , Santamaria Amato Luigi
Published: October 2020

Frequency modulated continuous wave (FMCW) laser detection and ranging is a technique for absolute distance measurements with high performances in terms of resolution, non-ambiguity range, accuracy and fast detection. It is based on a simple experimental setup, thus resulting in cost restraint with potential wide spread, not only limited to research institutions. The technique has been widely studied and improved both in terms of experimental setup by absolute reference or active stabilization and in terms of data analysis. Very recently a multi-wavelength approach has been exploited, demonstrating high precision and non ambiguity range. The variability of refractive index along the path was not taken into account with consequent degradation of range accuracy. In this work we developed a simple model able to take into account refractive index effect in multi-wavelength FMCW measurement. We performed a numerical simulation in different atmospheric conditions of temperature, pressure, humidity and CO2 concentration showing a net improvement of range accuracy when refractive index modeling is used.
Recycling of a Biodegradable Polymer Blend
Authors: La Mantia Francesco Paolo , Botta Luigi , Mistretta Maria Chiara , Di Fiore Antonino , Titone Vincenzo
Published: October 2020

Mechanical recycling is one of the possible ways to enhance the value of postconsumer plastic materials. However, the final performance of the recycled material will strongly depend on the quality of the selection made on the recycled product and on the degradation of the properties. In this context, the present study examines the effect of reprocessing for five successive extrusion cycles on the rheological, mechanical and thermal properties of a poly(butylene adipate-co-terephthalate) (PBAT)-based blend on samples reprocessed in both dry and wet conditions. The results showed that when the sample was processed after drying, degradation of the material was less than when it was processed in wet conditions. However, the experimental results showed that the decrease of rheological and mechanical properties was not so dramatic, and therefore the material could be reused in both cases.
Flexible Nanocomposites Based on Polydimethylsiloxane Matrices with DNA-Modified Graphene Filler: Curing Behavior by Differential Scanning Calorimetry
Authors: Toto Elisa , Laurenzi Susanna , Santonicola Maria Gabriella
Published: October 2020

Novel silicone-based nanocomposites with varied elastic properties were prepared by blending standard polydimethylsiloxane (PDMS) with a lower viscosity component (hydroxyl-terminated PDMS) and integrating a graphene nanoplatelets (GNP) filler modified by strands of deoxyribonucleic acid (DNA). The curing behavior of these nanocomposites was studied by dynamic and isothermal differential scanning calorimetry. The activation energies of the polymerization reactions were determined using the Kissinger method and two model-free isoconversional approaches, the Ozawa–Flynn–Wall and the Kissinger–Akahira–Sunose methods. Results show that the complex trend of the curing behavior can be described using the isoconversional methods, unveiling lower activation energies for the nanocomposites with standard PDMS matrices. The role of the DNA modification of graphene on the curing behavior is also demonstrated. The curing reactions of the nanocomposites with the PDMS matrix are favored by the presence of the GNP–DNA filler. PDMS/PDMS–OH blends generate softer nanocomposites with hardness and reduced elastic modulus that can be tuned by varying the amount of the filler.
The Active Life and the Contemplative Life in St. John of the Cross: The Mixed Life in the Teresian Carmelite Tradition
Authors: Serrán-Pagán y Fuentes Cristóbal
Published: October 2020

The prophetic and the mystical are two key theological concepts in St. John of the Cross. The aim of this article is precisely to shed light on the essential role that St. John of the Cross played in the history of Christianity by acknowledging the prophetic and the mystical dimensions of his life testimonies and writings. The notion of prophetic mysticism is not altogether foreign to the Carmelite tradition, especially following the prophetic example of Elijah. This article will then explore the intrinsic relationship that exists between the active life (Martha) and the contemplative life (Mary) in St. John of the Cross and in the Teresian Carmelite tradition.
Single-Stage Rotation-Decoupled Detector for Oriented Object
Authors: Zhong Bo , Ao Kai
Published: October 2020

Oriented object detection has received extensive attention in recent years, especially for the task of detecting targets in aerial imagery. Traditional detectors locate objects by horizontal bounding boxes (HBBs), which may cause inaccuracies when detecting objects with arbitrary oriented angles, dense distribution and a large aspect ratio. Oriented bounding boxes (OBBs), which add different rotation angles to the horizontal bounding boxes, can better deal with the above problems. New problems arise with the introduction of oriented bounding boxes for rotation detectors, such as an increase in the number of anchors and the sensitivity of the intersection over union (IoU) to changes of angle. To overcome these shortcomings while taking advantage of the oriented bounding boxes, we propose a novel rotation detector which redesigns the matching strategy between oriented anchors and ground truth boxes. The main idea of the new strategy is to decouple the rotating bounding box into a horizontal bounding box during matching, thereby reducing the instability of the angle to the matching process. Extensive experiments on public remote sensing datasets including DOTA, HRSC2016 and UCAS-AOD demonstrate that the proposed approach achieves state-of-the-art detection accuracy with higher efficiency.
Wide-Area Near-Real-Time Monitoring of Tropical Forest Degradation and Deforestation Using Sentinel-1
Authors: Hoekman Dirk , Kooij Boris , Quiñones Marcela , Vellekoop Sam , Carolita Ita , Budhiman Syarif , Arief Rahmat , Roswintiarti Orbita
Published: October 2020

The use of Sentinel-1 (S1) radar for wide-area, near-real-time (NRT) tropical-forest-change monitoring is discussed, with particular attention to forest degradation and deforestation. Since forest change can relate to processes ranging from high-impact, large-scale conversion to low-impact, selective logging, and can occur in sites having variable topographic and environmental properties such as mountain slopes and wetlands, a single approach is insufficient. The system introduced here combines time-series analysis of small objects identified in S1 data, i.e., segments containing linear features and apparent small-scale disturbances. A physical model is introduced for quantifying the size of small (upper-) canopy gaps. Deforestation detection was evaluated for several forest landscapes in the Amazon and Borneo. Using the default system settings, the false alarm rate (FAR) is very low (less than 1%), and the missed detection rate (MDR) varies between 1.9% ± 1.1% and 18.6% ± 1.0% (90% confidence level). For peatland landscapes, short radar detection delays up to several weeks due to high levels of soil moisture may occur, while, in comparison, for optical systems, detection delays up to 10 months were found due to cloud cover. In peat swamp forests, narrow linear canopy gaps (road and canal systems) could be detected with an overall accuracy of 85.5%, including many gaps barely visible on hi-res SPOT-6/7 images, which were used for validation. Compared to optical data, subtle degradation signals are easier to detect and are not quickly lost over time due to fast re-vegetation. Although it is possible to estimate an effective forest-cover loss, for example, due to selective logging, and results are spatiotemporally consistent with Sentinel-2 and TerraSAR-X reference data, quantitative validation without extensive field data and/or large hi-res radar datasets, such as TerraSAR-X, remains a challenge.
The Impact of the Flexibilization of Employment Histories on the Pension Adequacy in Poland
Authors: Jajko-Siwek Alicja
Published: October 2020

Flexibilization of employment history is a sign of our time. One of the real consequences of this phenomenon is the risk of a decrease in the level of future pension benefits, which can lead to the deprivation of pension system sustainability. Subsidies from the state budget will be necessary to the inadequate pensions. The paper aims to present how changes in earnings and employment breaks, caused by flexibilization of employment history, will impact the adequacy of pension benefits in Poland. In the research, different scenarios of employment history have been considered. As the method of research, we have used one of the data mining tools—the classification tree method with CART (Classification and Regression Trees) algorithm. The obtained results have shown a crucial role of stable individual promotion of earnings. Significant also is the level of earnings. The lower earnings can be compensated by long periods of seniority or by higher retirement age. Any breaks in work will lead to a reduction in the level of pension benefits and difficulties in maintaining adequacy. The suggestion from the study is that even if you are unemployed or receive a low salary, you should leave at least a low contribution to the pension system.
Implementation of SDGs in University Teaching: A Course for Professional Development of Teachers in Education for Sustainability for a Transformative Action
Authors: Collazo Expósito Leslie , Granados Sánchez Jesús
Published: October 2020

The University Jaume I of Castellon (Spain) launched the “ImpSDGup” course in 2017. The aim of this training course on professional education for sustainable development (ESD) skills and competences for higher education teachers is to help academics in reorienting their subjects’ curricula in order to contribute to the sustainable development goals of the United Nations’ Agenda 2030. The “ImpSDGup” course is based on the Training Model in Transformative Action for Sustainability (TMTAS) model that is structured in three main areas: the content on sustainability, the theoretical approaches, and the ESD teaching and learning methodologies. In this paper, we describe the design and the contents of the training course and we investigate the changes that participants of the course implemented in the design of their subject programs. The methodology of the study was based on content analysis. The main results show that most of the 55 university teachers that undertook the course in its three editions succeeded in transforming course objectives and that they incorporated some of the SDGs and several ESD active learning methodologies in their teaching. As a consequence of this, we consider that the course helps in enhancing university teachers’ ESD professional competences.
The Role of Public Governance in the Pursuit of Sustainable Development of the ILVA Steel Plant: An Interpretative Framework
Authors: Turco Mario , Leopizzi Rossella
Published: October 2020

The aim of this paper was to investigate the role of public institutions in the pursuit of sustainable development in a case study of international relevance: Taranto’s ILVA steel plant, which is one of the biggest steel and iron centres in Europe. The case study was analysed through investigating the different aspects of sustainable development in the four phases of development of the steel plant, from public direct management to private management. The analysis, based on a series of unstructured data, was carried out by applying a triple bottom line approach and the total interpretative structuring model (TISM). Evidence shows how—in the absence of stable, coherent, strong and present public institutions, capable of reading the forces of the local and international context and of intervening with regulatory actions inspired by a planned and interiorized economic strategy—the market, left in the hands of the private entrepreneur only, is destined to fail, and the paths of multidimensional sustainable development stray away from the ambitions of modern states.
On Confinement and Quarantine Concerns on an SEIAR Epidemic Model with Simulated Parameterizations for the COVID-19 Pandemic
Authors: De la Sen Manuel , Ibeas Asier , Agarwal Ravi
Published: October 2020

This paper firstly studies an SIR (susceptible-infectious-recovered) epidemic model without demography and with no disease mortality under both total and under partial quarantine of the susceptible subpopulation or of both the susceptible and the infectious ones in order to satisfy the hospital availability requirements on bed disposal and other necessary treatment means for the seriously infectious subpopulations. The seriously infectious individuals are assumed to be a part of the total infectious being described by a time-varying proportional function. A time-varying upper-bound of those seriously infected individuals has to be satisfied as objective by either a total confinement or partial quarantine intervention of the susceptible subpopulation. Afterwards, a new extended SEIR (susceptible-exposed-infectious-recovered) epidemic model, which is referred to as an SEIAR (susceptible-exposed-symptomatic infectious-asymptomatic infectious-recovered) epidemic model with demography and disease mortality is given and focused on so as to extend the above developed ideas on the SIR model. A proportionally gain in the model parameterization is assumed to distribute the transition from the exposed to the infectious into the two infectious individuals (namely, symptomatic and asymptomatic individuals). Such a model is evaluated under total or partial quarantines of all or of some of the subpopulations which have the effect of decreasing the number of contagions. Simulated numerical examples are also discussed related to model parameterizations of usefulness related to the current COVID-19 pandemic outbreaks.
In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses
Authors: Checkmahomed Liva , Padey Blandine , Pizzorno Andrés , Terrier Olivier , Rosa-Calatrava Manuel , Abed Yacine , Baz Mariana , Boivin Guy
Published: October 2020

Two antiviral classes, the neuraminidase inhibitors (NAIs) and polymerase inhibitors (baloxavir marboxil and favipiravir) can be used to prevent and treat influenza infections during seasonal epidemics and pandemics. However, prolonged treatment may lead to the emergence of drug resistance. Therapeutic combinations constitute an alternative to prevent resistance and reduce antiviral doses. Therefore, we evaluated in vitro combinations of baloxavir acid (BXA) and other approved drugs against influenza A(H1N1)pdm09 and A(H3N2) subtypes. The determination of an effective concentration inhibiting virus cytopathic effects by 50% (EC50) for each drug and combination indexes (CIs) were based on cell viability. CompuSyn software was used to determine synergism, additivity or antagonism between drugs. Combinations of BXA and NAIs or favipiravir had synergistic effects on cell viability against the two influenza A subtypes. Those effects were confirmed using a physiological and predictive ex vivo reconstructed human airway epithelium model. On the other hand, the combination of BXA and ribavirin showed mixed results. Overall, BXA stands as a good candidate for combination with several existing drugs, notably oseltamivir and favipiravir, to improve in vitro antiviral activity. These results should be considered for further animal and clinical evaluations.
Autoreactivity of Broadly Neutralizing Influenza Human Antibodies to Human Tissues and Human Proteins
Authors: Khurana Surender , Hahn Megan , Klenow Laura , Golding Hana
Published: October 2020

Broadly neutralizing monoclonal antibodies (bNAbs) against conserved domains in the influenza hemagglutinin are in clinical trials. Several next generation influenza vaccines designed to elicit such bNAbs are also in clinical development. One of the common features of the isolated bNAbs is the use of restricted IgVH repertoire. More than 80% of stem-targeting bNAbs express IgVH1-69, which may indicate genetic constraints on the evolution of such antibodies. In the current study, we evaluated a panel of influenza virus bNAbs in comparison with HIV-1 MAb 4E10 and anti-RSV MAb Palivizumab (approved for human use) for autoreactivity using 30 normal human tissues microarray and human protein (>9000) arrays. We found that several human bNAbs (CR6261, CR9114, and F2603) reacted with human tissues, especially with pituitary gland tissue. Importantly, protein array analysis identified high-affinity interaction of CR6261 with the autoantigen “Enhancer of mRNA decapping 3 homolog” (EDC3), which was not previously described. Moreover, EDC3 competed with hemagglutinin for binding to bNAb CR6261. These autoreactivity findings underscores the need for careful evaluation of such bNAbs for therapeutics and stem-based vaccines against influenza virus.
Evolutionary Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reveals Genomic Divergence with Implications for Universal Vaccine Efficacy
Authors: Yellapu Nanda Kumar , Patel Shachi , Zhang Bo , Meier Richard , Neums Lisa , Pei Dong , Xia Qing , Rotich Duncan , Zimmermann Rosalyn C. , Nissen Emily , Bell-Glenn Shelby , Shae Whitney , Hu Jinxiang , Chalise Prabhakar , Chollet-Hinton Lynn , Koestler Devin C. , Thompson Jeffery A.
Published: October 2020

Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is one of the pressing contemporary public health challenges. Investigations into the genomic structure of SARS-CoV-2 may inform ongoing vaccine development efforts and/or provide insights into vaccine efficacy to fight against COVID-19. Evolutionary analysis of 540 genomes spanning 20 different countries/territories was conducted and revealed an increase in the genomic divergence across successive generations. The ancestor of the phylogeny was found to be the isolate from the 2019/2020 Wuhan outbreak. Its transmission was outlined across 20 countries/territories as per genomic similarity. Our results demonstrate faster evolving variations in the genomic structure of SARS-CoV-2 when compared to the isolates from early stages of the pandemic. Genomic alterations were predominantly located and mapped onto the reported vaccine candidates of structural genes, which are the main targets for vaccine candidates. S protein showed 34, N protein 25, E protein 2, and M protein 3 amino acid variations in 246 genomes among 540. Among identified mutations, 23 in S protein, 1 in E, 2 from M, and 7 from N protein were mapped with the reported vaccine candidates explaining the possible implications on universal vaccines. Hence, potential target regions for vaccines would be ideally chosen from the structural regions of the genome that lack high variation. The increasing variations in the genome of SARS-CoV-2 together with our observations in structural genes have important implications for the efficacy of a successful universal vaccine against SARS-CoV-2.
Addressing Challenges of Urban Water Management in Chinese Sponge Cities via Nature-Based Solutions
Authors: Qi Yunfei , Chan Faith Ka Shun , Thorne Colin , O’Donnell Emily , Quagliolo Carlotta , Comino Elena , Pezzoli Alessandro , Li Lei , Griffiths James , Sang Yanfang , Feng Meili
Published: October 2020

Urban flooding has become a serious issue in most Chinese cities due to rapid urbanization and extreme weather, as evidenced by severe events in Beijing (2012), Ningbo (2013), Guangzhou (2015), Wuhan (2016), Shenzhen (2019), and Chongqing (2020). The Chinese “Sponge City Program” (SCP), initiated in 2013 and adopted by 30 pilot cities, is developing solutions to manage urban flood risk, purify stormwater, and provide water storage opportunities for future usage. Emerging challenges to the continued implementation of Sponge Cities include (1) uncertainty regarding future hydrological conditions related to climate change projections, which complicates urban planning and designing infrastructure that will be fit for purpose over its intended operating life, and (2) the competing priorities of stakeholders and their reluctance to make trade-offs, which obstruct future investment in the SCP. Nature-Based Solutions (NBS) is an umbrella concept that emerged from Europe, which encourages the holistic idea of considering wider options that combine “Blue–Green” practices with traditional engineering to deliver “integrated systems of Blue–Green–Grey infrastructure”. NBS includes interventions making use of natural processes and ecosystem services for functional purposes, and this could help to improve current pilot SCP practices. This manuscript reviews the development of the SCP, focusing on its construction and design aspects, and discusses how approaches using NBS could be included in the SCP to tackle not only urban water challenges but also a wide range of social and environmental challenges, including human health, pollution (via nutrients, metals, sediments, plastics, etc.), flood risk, and biodiversity.
The Water-Saving Strategies Assessment (WSSA) Framework: An Application for the Urmia Lake Restoration Program
Authors: Shadkam Somayeh , van Oel Pieter , Kabat Pavel , Roozbahani Amin , Ludwig Fulco
Published: October 2020

Increases in water demand often result in unsustainable water use, leaving insufficient amounts of water for the environment. Therefore, water-saving strategies have been introduced to the environmental policy agenda in many (semi)-arid regions. As many such interventions failed to reach their objectives, a comprehensive tool is needed to assess them. We introduced a constructive framework to assess the proposed strategies by estimating five key components of the water balance in an area: (1) Demand; (2) Availability; (3) Withdrawal; (4) Depletion and (5) Outflow. The framework was applied to assess the Urmia Lake Restoration Program (ULRP) which aimed to increase the basin outflow to the lake to reach 3.1 × 109 m3 yr−1. Results suggested that ULRP could help to increase the Outflow by up to 57%. However, successful implementation of the ULRP was foreseen to be impeded because of three main reasons: (i) decreasing return flows; (ii) increased Depletion; (iii) the impact of climate change. Decreasing return flows and increasing Depletion were expected due to the introduction of technologies that increase irrigation efficiency, while climate change could decrease future water availability by an estimated 3–15%. We suggest that to reach the intervention target, strategies need to focus on reducing water depletion rather than water withdrawals. The framework can be used to comprehensively assess water-saving strategies, particularly in water-stressed basins.
Modeling the Influence of Public Risk Perceptions on the Adoption of Green Stormwater Infrastructure: An Application of Bayesian Belief Networks Versus Logistic Regressions on a Statewide Survey of Households in Vermont
Authors: Ren Qing , Zia Asim , Rizzo Donna M. , Mathews Nancy
Published: October 2020

There is growing environmental psychology and behavior literature with mixed empirical evidence about the influence of public risk perceptions on the adoption of environmentally friendly “green behaviors”. Adoption of stormwater green infrastructure on residential properties, while costlier in the short term compared to conventional greywater infrastructure, plays an important role in the reduction of nutrient loading from non-point sources into freshwater rivers and lakes. In this study, we use Bayesian Belief Networks (BBNs) to analyze a 2015 survey dataset (sample size = 472 respondents) about the adoption of green infrastructure (GSI) in Vermont’s residential areas, most of which are located in either the Lake Champlain Basin or Connecticut River Basin. Eight categories of GSI were investigated: roof diversion, permeable pavement, infiltration trenches, green roofs, rain gardens, constructed wetlands, tree boxes, and others. Using both unsupervised and supervised machine learning algorithms, we used Bayesian Belief Networks to quantify the influence of public risk perceptions on GSI adoption while accounting for a range of demographic and spatial variables. We also compare the effectiveness of the Bayesian Belief Network approach and logistic regression in predicting the pro-environmental behaviors (adoption of GSI). The results show that influencing factors for current adoption differ by the type of GSI. Increased perception of risk from stormwater issues is associated with the adoption of rain gardens and infiltration trenches. Runoff issues are more likely to be considered the governments’ (town, state, and federal agencies) responsibility, whereas lawn erosion is more likely to be considered the residents’ responsibility. When using the same set of variables to predict pro-environmental behaviors (adoption of GSI), the BBN approach produces more accurate predictions compared to logistic regression. The results provide insights for further research on how to encourage residents to take measures for mitigating stormwater issues and stormwater management.
Medición del grado de competencia en el mercado de Afores: la aplicación del enfoque no paramétrico de la NOIE
Authors: Almendárez Carreón Óscar Iván , Arteaga García Julio César
Published: October 2020

Este trabajo estudia la competencia entre las Administradoras de Fondos para el Retiro de México. Para tal efecto, se utiliza la metodología del enfoque no paramétrico de la Nueva Organización Industrial Empírica propuesto por Panzar y Rosse (1987) para estimar el grado de competencia entre estas empresas. Se utiliza información financiera anual disponible en la Comisión Nacional del Sistema de Ahorro para el Retiro para el periodo 2012 – 2018. Los resultados indican que, en ese periodo, la industria (1) podría haberse comportado como un cartel y (2) está en equilibrio de largo plazo.
Rendimiento académico y habilidades de estudiantes en escuelas públicas y privadas: evidencia de los determinantes de las brechas en aprendizaje para México
Authors: Moreno Treviño Jorge O. , Cortez Soto Sara N.
Published: October 2020

Se analizan los determinantes del rendimiento académico en estudiantes de educación secundaria básica obligatoria en escuelas públicas y privadas en México, identificando también las fuentes de diferencias entre ambos sistemas educativos. Se emplean los datos de PISA 2012, se estiman los diferentes efectos tratamiento propuestos originalmente por Heckman y Vytlacil (2005) y se aplica al contexto de educación y aprendizaje desarrollado por Moreno (2009). Las estimaciones sugieren que existe un impacto positivo en cerrar la brecha educativa entre escuelas, de factores como el índice socioeconómico, la educación de la madre y en menor medida, la educación del padre, de igual manera, que la madre del alumno viva en casa. También, las estimaciones muestran evidencia de que existe un sesgo de selección hacia la pertenencia en un tipo de escuela, es decir, las características socioeconómicas de las familias de los alumnos son determinantes en la asignación de éstos entre escuelas públicas o privadas. Una potencial fuente de limitación es el diseño muestral de PISA, que no considera representatividad a nivel estatal o municipal. Una conclusión destacable desde la perspectiva de política pública es que la educación preescolar tiene un impacto positivo en el rendimiento académico y, además, reduce la brecha en los resultados de aprendizaje de estudiantes entre ambos tipos de escuela.
Nonsendromik İşitme Kayıplı Olgularda GJB2 Mutasyon Dağılımı
Authors: ATİK Tahir , AKGÜN Bilçağ , IŞIK Esra , ÖZKINAY Feriştah Ferda
Published: October 2020

Giriş: İşitme kaybı, popülasyonda 1/500-1000 sıklıkta rastlanan en sık görülen duyu kusurudur. Herediter işitme kayıplarının yaklaşık %25’i sendromiktir. Nonsendromik olan kısımda ise kalıtım pateni %80 otozomal resesif, geri kalan %20 otozomal dominant şeklindedir. Otozomal resesif nonsendromik işitme kaybı olgularının %20-40’ında, bir “sıkı bağlantı” proteini olan Connexin 26’yı (Cx26) kodlayan GJB2 genindeki mutasyonlar tablodan sorumlu olarak tespit edilmektedir.
Bu çalışmada, otozomal resesif NSI şüphesiyle, 2012-2019 yılları arasında GJB2 moleküler analizi yapılan 146 olgunun sonuçları geriye dönük olarak incelenerek, GJB2 mutasyon spektrumunun belirlenmesi amaçlanmıştır.
Gereç ve yöntem: İşitme kaybı şikayeti ile başvuran 146 olgunun GJB2 geninin ekzonik ve ekzon-intron yapışma bölgeleri Sanger dizi analizi yöntemi ile dizilenmiştir.
Bulgular: 35 olguda GJB2 geninde homozigot ya da birleşik heterozigot mutasyon saptanmıştır. En sık saptanan mutasyon 2. ekzonda yer alan c.35delG değişikliğidir. Saptanan diğer mutasyonlar ise; c.299_300delAT, c.551G>C, c.334_335delAA, c.109 G>A, c.358_360delGAG, c.71G>A şeklindedir.
Sonuç: Nonsendromik işitme kaybının etiyolojisinde en sık olarak GJB2 geni mutasyonları saptanmaktadır ve bu genin dizi analizi tanı algoritmasında ilk sırada yer almaktadır. Ayrıca çalışmamız sonucunda, nonsendromik herediter işitme kaybı ile ilişkili GJB2 genindeki saptanılan mutasyonlar paylaşılarak ülkemizdeki mutasyon spektrumunun incelenmesine katkıda bulunulmuştur.
Changes in the Morphological, Rheological, and Biochemical Blood Indicators in Triathletes
Authors: Teległów Aneta , Marchewka Jakub , Tota Łukasz , Ptaszek Bartłomiej , Pilch Wanda , Pałka Tomasz , Mucha Dariusz , Kubica Jadwiga , Aleksander-Szymanowicz Paulina , Marchewka Anna
Published: October 2020

The aim of this study was to assess how the influence of intense physical effort changes the morphological, rheological, and biochemical blood indicators in triathletes. The study group comprised 10 triathletes aged 30-45 years, members of the Active Side of Life Association (Kraków,
Poland). Venous blood was collected from the study participants twice, before and after the DiablakBeskid Extreme Triathlon 2016 (the Carpathians, Poland), and once from the control group for analysis of the selected blood indicators. Statistically significant changes were observed in the
study group before and after the triathlon in morphological blood indicators, in the elongation index at the shear stress of 0.30 and 0.58 Pa, in levels of electrolytes, creatinine (mmol/l), serum protein parameters, and high-sensitivity troponin (ng/l). No such differences were reported for
the remaining parameters. In turn, when comparing the study group before the triathlon with the control group, statistically significant differences were recorded in MCHC (g/dl), in the elongation index at the shear stress of 0.30 and 0.58 Pa, and Cl– (mmol/l) levels. No such
differences were reported for the remaining parameters. Blood haematological and biochemical indicators in individuals that participate in triathlons characterize the actual range and direction of effort-related changes well and allow for the diagnosis of transient adaptive effects. Rheological
parameters, involving the evaluation of erythrocyte deformability and aggregation, are useful for monitoring the particularly undesirable, short- and long-term effects of practicing extreme sports such as triathlons.
Impact of climate change on the environmental security of the Mekong Rever Delta area
Authors: Thi Ta Dinh , Trung Ta Van , Oanh Phan Thi Kim , Thang Do Nam , Nga Dinh Thi
Published: October 2020

Affected strongly by climate change, Mekong Delta faces lots of challenges in the development process. By means of inheritance, synthesis and statistics, and sociological investigation methods, the article has figured out that Mekong Delta is a vulnerable area due to climate change and exogenous factors, such as water security; environmental pollution; degradation of forest resources and biodiversity. It is necessary to establish a long-term framework for climate change adaptation and national security towards sustainable development.
A STUDY OF STAKEHOLDER PERSPECTIVES OF ENTERPRISE ARCHITECTURE METHODOLOGY (TOGAF FRAMEWORK)
Authors: Zahra Denada Fatimah , Sinambela Yunita , Takwim Ahsani
Published: October 2020

Enterprise architecture is a method or explanation of how to plan, compile, structure, and realize company structures, business processes, information systems, and related infrastructure as well as an explanation of how to design systems that can support business needs and related technology to make vision and mission achieve results. targeted. The framework used in this research is TOGAF and FEAF. TOGAF has a detailed and comprehensive framework and has a methodology that supports its application but is invincible from a stakeholder point of view. The aim of this study is to develop two frameworks by comparing the differences that each Framework has from the perspective of stakeholders. The research methodology begins with a literature study and analysis with a comparison of the TOGAF and FEAF Frameworks. The results showed that. The final result of this research is the TOGAF framework with the components that are owned by FEAF from the perspective of the stakeholders so as to produce a TOGAF framework that suits the specific needs of the organization
INVENTORY INFORMATION SYSTEM DESIGN AT PT. ARSEN KUSUMA INDONESIA JAKARTA
Authors: Sarkawi Dahlia , Ramdani Dani , Oktaviani Anggi , Novianti Deny
Published: October 2020

An inventory Information System is an Information System that provides information from several processes including procurement of goods, warehousing, and reporting. Therefore it is necessary to create an Inventory Information System application to improve the company's performance process which originally became computerized which will result in more detailed reports. The creation of this application is done using data collection, system planning, system analysis, system design, and database. Application program creation was developed with PHP and Waterfall model as well as tested using black-box testing. And it is expected that the manufacture of this application can facilitate the company in processing the inventory of goods, then in this research was made Designing Inventory Information System At PT. Arsen Kusuma Indonesia Jakarta.
DECISION SUPPORT SYSTEM FOR SELECTION OF EXEMPLARY EMPLOYEES AT PT. SINAR ASIA PERKASA
Authors: Syahriani Syahriani , Nurmah Nurmah , Indriyani Luthfi
Published: October 2020

Sinar Asia Perkasa is a manufacturing company, where this company is always required to innovate and improve the quality and quality of its products. Because of this, the company PT. Sinar Asia Perkasa must improve itself to get employees who have high quality and work productivity. Employees are one of the most important parts of a company that must be managed properly. To get employees of the highest quality, a process is needed that can automatically provide recommendations in selecting exemplary employees at PT. Sinar Asia Perkasa, namely by establishing a Decision Support System. This Decision Support System is expected to assist in objectively selecting employees. Making this Decision Support System using the Profile Matching method with several criteria, namely aspects of the discipline, aspects of integrity, aspects of cooperation, and aspects of work performance. Then for the final stage of this method is ranking.
HERENCIA DE LA POLIEMBRIONÍA EN DOS POBLACIONES EXPERIMETALES DE MAÍZ
Authors: Rebolloza-Hernández Hermes , Espinoza-Velázquez José , Sámano-Garduño Daniel , Zamora-Villa Víctor M.
Published: October 2020

Aquí se plantea que la poliembrionía (PE) que ocurre en dos poblaciones de maíz (Zea mays L.) es controlada por dos loci epistáticos, donde basta la presencia de un alelo dominante de cualquiera de ellos para expresar la condición normal de plántula (acción génica duplicada), por lo que la poliembrionía se expresa sólo con el genotipo doble homocigótico recesivo. El análisis genético incluyó progenies F1, F2 y RC1 de cruzas de las poblaciones IMM-UAAAN-BAP (D) e IMM-UAAAN-NAP (C) con ocho materiales exóticos, los cuales fueron seis híbridos comerciales, un híbrido simple experimental y una población del CIMMYT. Las 16 cruzas F1 fueron obtenidas en Tepalcingo, Mor., en 2007; las F2 en Buenavista, Coah., en 2008; y las retrocruzas (RC1) en Buenavista, en 2009. La evaluación de la PE en progenies F1 y F2 se hizo en invernadero y campo, bajo un diseño de bloques completos al azar con 4 o 5 repeticiones, y la RC1 en invernadero. La segregación de la PE en F2 se probó con la hipótesis de dos loci recesivos hipostáticos 15:1 (progenie No-PE vs. progenie PE), y para las retrocruzas la hipótesis fue 12:4. Como se esperaba, la PE no se expresó en F1 pero sí en F2 y RC1, en proporciones de 3 a 7 % y de 13 a 22 %, respectivamente. Estas proporciones son compatibles con las hipótesis planteadas, pero con la consideración de penetrancia incompleta la cual se pudo observar en montos de 10 a 50 %, según la fuente de germoplasma exótico en combinación con las poblaciones PE. Los resultados de pruebas de χ2 aplicadas a las proporciones observadas en los dos tipos de análisis estadístico, apoyan la propuesta de herencia de la PE en las dos poblaciones de maíz bajo estudio.
VARIACIÓN MORFOLÓGICA DE SEMILLAS DE Taxus globosa Schltdl. PROVENIENTES DE DOS REGIONES GEOGRÁFICAS DE MÉXICO
Authors: Ramírez-Sánchez Susana E. , López-Upton Javier , García-de los Santos Gabino , Vargas-Hernández J. Jesús , Hernández-Livera Adrián , Ayala-Garay Óscar J.
Published: October 2020

Taxus globosa Schltdl. es la única especie del género Taxus que se encuentra en México y está protegida por el Gobierno Mexicano. Su corteza y hojas contienen taxol, un compuesto de gran valor por su función como anticancerígeno. Su regeneración natural es por semillas que germinan de manera escasa y presentan latencia. El presente estudio se hizo para conocer la variación morfológica existente en las semillas de Taxus globosa y determinar si la latencia es causada por algún factor físico. Se utilizaron semillas procedentes de dos regiones de México: norte (Nuevo León) y centro (Hidalgo y Querétaro). Se midieron las dimensiones de la semilla (largo, ancho, área, perímetro y proporción embrión-megagametofito) mediante análisis de imagen, así como peso volumétrico y peso de 1000 semillas. Para evaluar las características físicas de la testa, las semillas se sometieron a una prueba de escarificacion con ácido sulfúrico durante 5, 10, 15, 20, 25 y 30 min seguida de una prueba de viabilidad con tetrazolio; también se midió la dureza de la testa y la velocidad de imbibición. Se encontraron diferencias geográficas en el tamaño de la semilla (28 % más grande (P ≤ 0.05) en la región norte). La proporción de embrión-megagametofito fue de sólo 4 % en el norte y de 3 % en el centro; la semilla de ambas regiones sólo soportó 5 min en H2SO4, y la testa en las semillas del norte es más dura que en las del centro (1.29 vs. 0.86 kg cm-2). La semilla del norte absorbe más agua que la del centro. La semilla no necesita escarificación para ablandar la testa. El embrión en T. globosa se considera subdesarrollado y posible causa de la latencia de la semilla.
القيمة القانونية للشروط غير المباشرة المقيدة من أحكام ضمان العيب الخفي في البيوع
Authors: عبد الكريم محمود , دوديـــن محمود
Published: October 2020

تناولت الدراسة مجموعة من الصور غير المباشرة المعفية من ضمان العيب الخفي في عقود البيع، وبشكل خاص عندما يكون العقد بين طرفين أحدهما مهني ومحترف والآخر مستهلك أو شخص عادي. اتعبت الدراسة المنهج التحليلي المقارن من خلال بيان آراء الفقه والقضاء بشأن موضوعها، وتحليلها في إطار مجلة الأحكام العدلية المطبقة في فلسطين، والقوانين المدنية في كل من مصر والأردن وقطر، سعيا لاستخلاص القيمة القانونية للشروط محل البحث، وبيان إلى أي حد ساهم المشرّع والقضاء في تحقيق التوازن الاقتصادي للعقد بين طرفيه.
الطبيعة القانونية للبطلان في فترة الريبة
Authors: شاكر رشا كيلان
Published: October 2020

تمثل فترة الريبة المدة الواقعة بين تاريخ بدأ التوقف عن الدفع وتاريخ صدور حكم شهر الافلاس وان التصرفات التي يقوم بها التاجر المدين في هذه الفترة هي تصرفات مشوبة بالشك فبمجرد ان يتوقف التاجر المدين عن دفع ديونه يجعل تصرفاته يشوبها الاضطراب , اذ قد يعمد الى الاضرار بدائنيه او تفضيل بعضهم مما يضر بمصالح الاخرين لأنه يشعر بدنوه من الافلاس او انه قد اشرف عليه , لذا ارتاب المشرع من تصرفاته في هذه الفترة التي تعد اخطر الفترات واشدها ضررا على الدائنين فنص على بطلان التصرفات الصادرة من المدين خلال هذه الفترة بطلانا وجوبيا او جوازيا . وهدف المشرع من ذلك هو حماية جماعة الدائنين وان يكون عدم نفاذ التصرف في فترة الريبة اشمل وايسر مما هو مقرر للدائنين في القواعد العامة من الحق في طلب عدم نفاذ التصرف عن طريق الدعوى البوليصية . لذا كان لزاما بيان طبيعة البطلان وتحديد فترة الريبة ومن ثم التطرق للبطلان الوجوبي والجوازي من حيث توافر الشروط والتصرفات الخاضعة لهذين النوعين من البطلان .
أثر جائحة كورونا على تنفيذ الالتزامات التعاقدية
Authors: حسن حيدر فليح
Published: October 2020

ان الازمة الصحية العالمية الناشئة عن انتشار فيروس كورونا (والذي وصفته منظمة الصحة العالمية في 30/كانون الثاني/2020 بانه حالة طواريء صحية عامة مُثيرة للقلق الدولي، ثم عادت لتُسبغ عليه وصف الجائحة   pandemic  في 11/آذار/2020) وما أتخذته السطات الحكومية في دول العالم المختلفة من تدابير وأجراءات متفاوته (سواء بمستواها الاعلى من فرض حظر التجوال الشامل او ما اطلق عليه عالميا بالحجر المنزلي وبالتالي تعطيل كافة القطاعات والانشطة في الدولة (عامة كانت ام خاصة) باستثناء بعض القطاعات من قبيل القطاع الصحي والاعلامي والامني، او بمستوى اقل من ذلك من قبيل تخفيض نسب العمل في القطاعات المختلفة بنسب تتفاوت من دولة الى اخرى كان تكون السماح ب 25% فقط من نسب العمال بالعمل مع فروض قيود التباعد الاجتماعي ومراعاة شروط الصحة العامة وما لذلك من تأثير على قلة الانتاج). كان له تأثير كبير بل وكبير جدا على تنفيذ الالتزامات التعاقدية سواء على مستوى العلاقات التعاقدية الدولية اوحتى الوطنية (المحلية)، وسواء فيما يتعلق بالارهاق الناشيء عن الاستمرار بتنفيذ تلك الالتزامات، او التوقف عن تنفيذها بشكل مؤقت ، او حتى بشكل نهائي. من هنا جاءت هذه الورقة البحثية لبيان اثر جائحة كورونا على تنفيذ الالتزامات التعاقدية
La práctica cultural de modificar el cuerpo como un texto de información e interpretación social para la antropología física:
Authors: Yépez Vásquez Rosaura , Arzápalo Marín Ramón
Published: October 2020

En muy diversas culturas se mantienen arraigadas costumbres ancestrales que han reforzado y refuerzan aún su identidad étnica a través de la modificación del cuerpo, con especial referencia a la cabeza, como es el caso de las culturas andinas de Perú. Los signos comprendidos en estos textos culturales los podemos decodificar y reconstruir para dar sentido y valor a la trayectoria del hombre: creador y usuario de símbolos por excelencia
Los contratiempos de la democracia procedimental en México
Authors: Figueroa Ibarra Carlos , Moreno Velador Octavio Humberto
Published: October 2020

A partir de los conceptos básicos de la llamada "democracia procedimental", en este trabajo se hace una revisión de los problemas que se presentaron en México entre los años 2003 y 2006 previó a las elecciones presidenciales. El conjunto de estos problemas relacionados a una campaña de descredito hacia el candidato del principal partido de izquierda, permite demostrar algunos de los retos más importantes de la naciente institucionalidad democrática mexicana. Como elemento central en la resolución de este período, la "protesta popular" jugó un papel importante en el cambio de política oficial federal, convirtiéndose posteriormente en el principal impulso de la candidatura del partido de izquierda. Estos sucesos y su trascendencia en el escenario político sirven esencialmente para reflexionar sobre las condiciones del tipo de democracia existente en México y América Latina a luz de los procesos de democratización y neoliberalismo en el continente.
Contra la devolución:
Authors: Padawer Ana
Published: October 2020

En este trabajo se realiza una reflexión metodológica sobre la relevancia que, para la investigación en el contexto de la gestión pública de la educación en Argentina, adquieren los aportes de la etnografía. En particular, se considera la importancia de la problematización acerca de la implicación del sujeto con el objeto de conocimiento, que si bien tiene su espacio en el contexto académico, en los ámbitos de producción de conocimiento dentro del Estado resulta frecuentemente relegada.
Metamorfosis de los modelos evangelizadores en el Chaco Central:
Authors: Braticevic Sergio
Published: October 2020

A partir de la proliferación de las ONGs y el agenciamiento de diversos programas de desarrollo, el modelo evangelizador logró nuevamente contener parte de las demandas de la población indígena, pese al desgaste sufrido por las iglesias en la zona. Del mismo modo, generó diques de contención a la inestabilidad producida entre el avance de la frontera agraria y las comunidades locales, estableciendo la continuidad de los desequilibrios espaciales propiciados por la explotación de economías de enclave.
Pueblos originarios y políticas de reconocimiento en Argentina
Authors: Trinchero Héctor Hugo
Published: October 2020

Las disposiciones jurídico-políticos que tienen incluso rango constitucional y garantizan el reconocimiento de los pueblos originarios argentinos cargan con el peso del sistema de representaciones que históricamente se ha construido en torno a los modos de representación de la identidad nacional. Una de las claves para comprender esta situación es la forma de ocupación del espacio rural, tanto el modelo histórico, como el reciente con la constante expansión de la frontera agraria para la producción de granos, especialmente soja, vinculada al mercado mundial. El objetivo de este artículo es dar cuenta de la situación actual de los pueblos originarios en la Argentina a través de un análisis conceptual y estadístico, y aportar a una caracterización del conflicto de representaciones e intereses que tiende a agudizarse día a día.
La construcción del relato mítico ancestral en el arte y la poesía mapuche actual
Authors: García Barrera Mabel
Published: October 2020

El arte mapuche actual se caracteriza por mezclar prácticas de la producción artística y del saber cultural mapuche ancestral como de la cultura occidental. En este sentido, la actual obra de arte se constituye en un topos agonístico donde se desplazan, significan y resignifican elementos y categorías, propias y ajenas, buscando definir una identidad; así, la obra se abre tanto hacia la recuperación de lo propio -a través del proceso de retradicionalización cultural-, como hacia la desvinculación de lo ajeno -a través del proceso de resistencia cultural-. En esta dinámica, el relato mítico ancestral se ubica como uno de los elementos artísticoculturales transversales donde reafirmar la diferencia cultural y al mismo tiempo como un importante vehiculador de las bases estéticas tradicionales. Desde este punto de vista, el presente trabajo busca saber cómo el actual proceso artístico y literario mapuche resignifica el relato mítico y en este proceso transforma o no algunas de las bases estéticas inscritas en él.
La mirada sobre el otro. Una aproximación acerca de la percepción de alumnos argentinos sobre la población chilena en Neuquén
Authors: Cerutti Ángel , González Cecilia
Published: October 2020

Este articulo se inscribe en el marco del proyecto de investigación "La mirada xenófoba. Migrantes chilenos en Neuquén. Discriminación y prejuicio. Una perspectiva actual", y en él se realiza un análisis de las posturas de alumnos del turno noche de una escuela secundaria respecto a la población chilena en el Neuquén; estos alumnos pertenecen a los sectores populares y concurren al CPEN Nº 8 de la localidad de Plottier, provincia del Neuquén- lugar donde se llevo a cabo el trabajo de campo. Las respuestas obtenidas reflejan actitudes de prejuicio antichileno. Se sostiene que el prejuicio se encuentra potenciado por la necesidad de "diferenciarse" de los que por algún rasgo pueden ser considerados "inferiores", frente a la creciente pauperización de los sectores medios y populares y que las limitadas políticas sociales y el desempleo contribuyen a retroalimentarlo.