bluuebunny/crossref_metadata_2025 huggingface dataset:
Engineering Wettability Transitions on Laser-Textured Shark Skin-Inspired Surfaces via Chemical Post-Processing Techniques
Authors: Lori Zoudani Elham , Nguyen Nam-Trung , Kashaninejad Navid
Published: November 2024

Surface wettability, the interaction between a liquid droplet and the surface it contacts, plays a key role in influencing droplet behavior and flow dynamics. There is a growing interest in designing surfaces with tailored wetting properties across diverse applications. Advanced fabrication tech-niques that create surfaces with unique wettability offer significant innovation potential. This study investigates the wettability transition of laser-textured anisotropic surfaces featuring shark skin-inspired microstructures using four post-processing methods: spray coating, isopropyl alcohol (IPA) treatment, silicone oil treatment, and silanization. The impact of each method on surface wettability was assessed through water contact angle measurements, scanning electron microscopy (SEM), and laser scanning microscopy. The results show a transition from superhydrophilic be-havior on untreated laser-textured surfaces to various (super)hydrophobic states following surface treatment. Chemical treatments produced different levels of hydrophobicity and anisotropy, with silanization achieving the highest hydrophobicity and long-term stability, persisting for one year post treatment. This enhancement is attributed to the low surface energy and chemical properties of silane compounds, which reduce surface tension and increase water repellence. In conclusion, this study demonstrates that post-processing techniques can effectively tailor surface wettability, ena-bling a wide range of wetting properties with significant implications for practical applications.
Establishing a Bridge between the Supervisor's Perception and the Employee's Behavior: A Study on the Influence Mechanism of a Supervisor's Perceived Organizational Support on a Salesperson's Career Initiative
Authors: Gai Yiran , Shi Guicheng , Liu Yu
Published: November 2024

The influences of a supervisor's perception and behavior on employee output constitute a significant issue that scholars are eager to explore; nevertheless, an effective connection between supervisors' perception and employees' positive behaviors is lacking. Therefore, we investigate the potentiality of such a connection based on social exchange theory and self-determination theory, whereby supervisors can establish an inclusive workplace environment upon receiving organizational support, leading salespeople to perceive a superior team atmosphere that engenders a sense of internal obligation, which eventually gives rise to proactive behavior. However, front-line salespeople demonstrate a considerable extent of autonomous decision-making conduct, and the determination of behavior for job engagement necessitates that each salesperson holds superior intrinsic motivation; accordingly, the moderating impact of the salesperson`s core self-evaluation is also probed in our study. Using Mplus 8.0 to analyze the matched survey of 50 team leaders and 299 employees, we ultimately discovered that the supervisor's perceived organizational support exerts a positive influence on the group-inclusive climate; a group-inclusive climate can enhance the felt obligation and career initiative of front-line salespeople; a supervisor's perceived organizational support can enable salespeople to perceive the inclusive climate of the group, engender their sense of obligation, and ultimately impact their career initiative; and a salesperson's core self-evaluation can significantly moderate the positive effects of the group-inclusive climate.
Generation of Rational Drug-Like Molecular Structures Through a Multiple-Objective Reinforcement Learning Framework
Authors: Zhang Xiangying , Gao Haotian , Qi Yifei , Li Yan , Wang Renxiao
Published: November 2024

As an appealing approach for discovering novel leads, the key advantage of de novo drug design lies in its ability to explore a much broader dimension of chemical space, without being confined to the knowledge of existing compounds. So far many generative models have been described in the literature, which have completely redefined the concept of de novo drug design. However, many of them lack practical value for real-world drug discovery. In this work, we have developed a graph-based generative model within a reinforcement learning framework, namely METEOR (Molecular Exploration Through multiplE-Objective Reinforcement). The backend agent of METEOR is based on the well-established GCPN model. To ensure the overall quality of the generated molecular graphs, we implemented a set of rules to identify and exclude undesired substructures. Importantly, METEOR is designed to conduct multi-objective optimization, i.e. simultaneously optimizing binding affinity, drug-likeness, and synthetic accessibility of the generated molecules under the guidance of a special reward function. We demonstrate in a specific test case that, without prior knowledge of true binders to the chosen target protein, METERO generated molecules with superior properties compared to those in the ZINC 250k data set. In conclusion, we have demonstrated the potential of METERO as a practical tool for generating rational drug-like molecules in the early phase of drug discovery.
Spatial Insights for Building Resilience: the TERIMAAS Framework for Bridging Scales in Multi-Hazard Assessment
Authors: Ugliotti Francesca Maria , Daud Muhammad , Iacono Emmanuele
Published: November 2024

In an era of increasingly abundant and granular spatial and temporal data, the traditional divide between environmental GIS and building-centric BIM scales is diminishing, offering an opportunity to enhance natural hazard assessment by bridging the gap between territorial impacts and effects on individual structures. This study addresses the challenge of integrating disparate data formats by establishing a centralised database as the foundation for a comprehensive risk assessment approach. A use case focusing on flood risk assessment for a public building in the Piedmont Region demonstrates the practical implications of this integrated methodology. The proposed TErritorial RIsk Management & Analysis Across Scale (TERIMAAS) framework utilises this centralised repository to store, process, and dynamically update diverse BIM and GIS datasets, incorporating real-time IoT-derived information. GIS spatial analysis assesses risk scores for each hazard type, providing insights into vulnerability and potential impacts. BIM data further refines this assessment by incorporating building and functional characteristics, enabling a comprehensive evaluation of resilience and risk mitigation strategies tailored to dynamic environmental conditions across scales. The results of the proposed scalable approach could provide a valuable understanding of the territory for policymakers, urban planners, and any stakeholder involved in disaster risk management and infrastructure resilience planning.
Niche Evolution and Conservation of a Chinese Endemic Genus Sinojackia (Styracaceae)
Authors: Feng Miao , Zhang Ji-Si
Published: November 2024

Climate change and human activities are expected to have a profound impact on the distribution of species, especially for narrow distributed species. Sinojackia is endemic distributed in eastern China, and all species are listed in Chinese protected wild species. Here, we reconstructed the phylogeny and estimated the divergence time of Sinojackia based on whole plastomes, conducted the niche evolution and predicted the potential habitat area of Sinojackia from LGM to future. Our results strongly supported the monophyly of Sinojackia based on the whole plastomes. This genus originated at middle Miocene and diversified since the late Miocene. Aridity index was a highest significant factor for their niche evolution, and the niche evolution rate increased slow since its divergence. Precipitation of warmest quarter was a main environmental variable affecting the distribution of Sinojackia in LGM, while human footprint is the main variable in near-current and 2081-2100. Compared to the current distribution of Sinojackia, the highly suitable distribution area contracted in LGM, but expand in the 2081-2100. This study provides potential areas for in situ conservation of Sinojackia.
Asbestos Evidence in Roman Buildings from Micia Archaeological Site (Romania)
Authors: Ion Rodica-Mariana , Barbu Marius Gheorghe , Gurgu Valentin Ion , Slamnoiu-Teodorescu Sofia , Gheboianu Anca Irina , Vasilievici Gabriel , Iancu Lorena , Grigorescu Ramona Marina , Alexandrescu Elvira
Published: November 2024

The Micia site, is recognized as an archaeological civil settlement that was inhabited, and soldiers from several troops, were stationed in the Roman camp. From the end of the 2nd century AD, the civil settlement was rebuilt, with residential areas, industrial areas, port, public baths (civilian and military), amphitheater, religious areas (temples) and enjoying the facilities of a city. In this regard, the present work will first address the composition of the samples taken from the Roman monuments identified in Micia area and will highlight for the first time for this Roman site the presence of a form of tremolite-asbestos. This paper analyzes for the first time the presence of traces of tremolite-asbestos in stone samples collected from Roman monument buildings extracted from quarries near the city of Deva and used in civil, military and funerary structures from Micia. Highly performant and sensitive analytical techniques have been used to put into evidence the tremolite-asbestos species, to identify the structure, composition and morphology of these minerals inside of the building materials from Roman monuments, as follows: optical, stereo and scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray fluorescence with wavelength dispersion (EDXRF), FTIR and Raman spectroscopy, thermal analysis (TGA/DTA). It is presumed that tremolite-asbestos species has been included in the material layers used as mortars at Micia settlement in order to protect these monuments.
Vascular Endothelial Growth Factor (VEGF) Family and the Immune System: Activators or Inhibitors?
Authors: Failla Cristina M. , Carbone Maria Luigia , Ramondino Carmela , Bruni Emanuele , Orecchia Angela
Published: November 2024

The vascular endothelial growth factor (VEGF) family includes key mediators of vasculogenesis and angiogenesis. VEGFs are secreted by various cells of epithelial and mesenchymal origin and by some immune cells in response to physiological and pathological stimuli. In addition, immune cells express VEGF receptors and/or coreceptors and can respond to VEGFs in an autocrine or paracrine manner. This immunological role of VEGFs has opened the possibility to use the VEGF inhibitors already developed to inhibit tumor angiogenesis also in combination approaches with different immunotherapies to enhance the action of effector T lymphocytes against tumor cells. This review aims at analyzing the current knowledge on the crosstalk between VEGFs and the immune system and at highlighting those aspects that still need to be further investigated.
Estimating Vertical Inertial Forces Inertia Compensation during Gait Rehabilitation Therapy
Authors: Ali Syed Muhammad Zubair , Munawar Hammad , Mahmood Atif
Published: November 2024

Gait trainers are increasingly used in rehabilitation for patients with lower extremity impairments; however, current control strategies often neglect the inertial forces from the body’s vertical motion, limiting effective force compensation. This results in deviations in the unloading force of rehabilitation devices, disrupting the patient’s natural gait. We introduce an estimation technique to predict vertical inertial forces generated by body movement, enabling rehabilitation robots to actively compensate for inertia during therapy. Our approach utilizes widely available sensors, such as smartphones, providing a cost-effective alternative to traditional multi-sensor setups, reducing wiring, and minimizing movement restrictions, thus enhancing data collection and preserving natural gait. Additionally, this technique has potential applications for Low Gravity training in NASA’s Active Response Gravity Offload System (ARGOS), supporting astronaut training by simulating reduced gravity conditions.
Diseño iconográfico, apropiación y propuestas de diseño de moda en Mata Ortiz.
Authors: Campos González Judith Angélica , Ariza Ampudia Silvia Verónica
Published: November 2024

La población de Mata Ortiz en el municipio de Casas Grandes, en Chihuahua, es un lugar que en las últimas décadas se constituyó como una comunidad de artesanos y alfareros que apropian, reinventan y reconfiguran la iconografía de vasijas paquimeitas en una interesante variedad de productos. Este texto tiene como objetivo mostrar, en dos diseños relacionados con el sector de la moda, cómo este grupo de alfareros construye nuevas propuestas visuales que mantienen significados importantes, pero que transforman las posibilidades iconográficas en nuevas visiones con componentes, singularidades, planos semióticos y efectos estéticos que plasman nuevos argumentos y valores para el consumo cultural. A través del análisis de dos piezas derivadas de la diversificación del consumo y utilizando un modelo semiótico, se describen creaciones que salen del concepto de artesanía para buscar un espacio en el mundo de la moda, y se da cuenta del dinamismo y evolución de los medios de un grupo de artesanos de la región en cuestión.
Hemerotecas necesarias para historiar el siglo XX juarense
Authors: Sánchez Reyes Darío Oscar
Published: November 2024

Cuando historiadores e investigadores desean abordar tópicos sobre Ciudad Juárez y su región fronteriza en el siglo xx, se enfrentan a una escasez y dispersión de archivos de periódicos y revistas impresos localmente en esa época, que dificultan su labor. En este artículo se muestra el resultado de una amplia exploración dirigida a comprobar la existencia y acceso a colecciones en hemerotecas públicas y acervos privados, a fin de propiciar un mayor número de estudios sobre el siglo pasado local, concluyendo que podría ser mejor historiado a través de la necesaria recuperación de la memoria hemerográfica juarense.
Wettability Evolution of Sandpacks with Clay Content during Long-Term Waterflooding: A Pore-Scale Contact Angle Characterization
Authors: Xi Chaodong , Gong Wenbo , Lu Xukang , Yang Guang , Ju Yang , Wang Moran
Published: November 2024

Wettability of rocks may undergo a dynamic evolution during long-term waterflooding. Existing studies usually assume a constant wettability property of rock and ignore the wettability evolution during long-term waterflooding, resulting in ambiguous recognition of residual oil resources. To uncover the wettability evolution within complex pore structure, the effects of clay content on local contact angles are addressed in the sandpacks during long-term waterflooding via in-situ computed tomography (CT) imaging experiments. In this study, the wettability evolution is quantitatively characterized by mean contact angle, contact angle hysteresis, and wettability representative element volume (REV) size. Based on surface roughness and clay deposition patterns, we propose a physical model to analyze the mechanism of wettability evolution. The results indicate that the contact angle distribution within the pore structure is heterogeneous while locally continuous. Water-clay turbid treatment is effective in altering the wetting state of sandpack to less water-wet, reducing the contact angle hysteresis, and enhancing the heterogeneity of contact angle distribution. Waterflooding makes the sandpacks more water-wet and decreases the heterogeneity of contact angle distribution. Transition of surface roughness and clay deposition patterns during waterflooding accounts for the contact angle alteration and determines the overall wettability evolution.
Study on the Mechanism of Stress Sensitivity and Retrograde Condensation Coupling Effect on Reservoir Depletion Development in Fractured-Vuggy Carbonate Rocks
Authors: Liu Yang , Pan Yi , Xiong Yu , Sun Yang , Liang Bin , Sun Lei
Published: November 2024

Deep and high-pressure carbonate gas condensate reservoirs develop a large number of cracks and holes, with strong interlayer heterogeneity and complex mechanisms. To clarify the fundamental reasons that affect the development efficiency of such condensate gas reservoirs, we take the typical fractured and vuggy carbonate rock reservoirs in China’s S condensate gas field as the object of study, and conduct experiments such as X-ray computed tomography (X-CT) scanning, high-temperature and high-pressure stress-sensitivity testing, and long-core depletion development experiments. From multiple parameters and perspectives, we describe the microscopic changes in the storage and seepage spaces of fractures and vuggy cores, as well as the changing patterns of the underground condensate oil and gas production. According to the research results, the increase in effective stress leads to the contraction and closure of the fractured and vuggy spaces in the core, resulting in a decrease in their size. Under deep, high-pressure conditions, carbonate reservoirs exhibit strong stress sensitivity, and the permeability of the core drops significantly with the increase in the formation’s effective stress. The coupling effect of stress sensitivity and retrograde condensation has different impacts on the development effect of different types of cores at different pressure stages. The vuggy cores experience greater changes in storage and seepage spaces, the overall permeability damage is strong, and the condensate oil recovery rate is ultimately lower than that of fractured cores. Therefore, it is of great significance to study the impact of stress sensitivity and retrograde condensation characteristics on the gas reservoir recovery rate. The research results can provide theoretical support for the efficient development of deep, fractured-vuggy carbonate condensate gas reservoirs.
Accounting for Negative Publicity in Project Economics
Authors: Holgate M. J. M. , Davies G. J. , Kerr S. A. , Johnston F. M. M.
Published: November 2024

Management

Summary

The high-profile publicity generated by the Greenpeace campaign against deep-sea disposal of the Brent Spar demonstrated the power of public opinion to affect corporate image and operational decisions. Regulatory approval is not the only constraint on the granting a "license to operate," and corporations now ignore stakeholder values at their peril. Although quantifying soft issues, such as negative publicity and stakeholder concerns, is difficult, there is an increasing need to integrate conventional economics with public opinion when evaluating different possible development options. This paper seeks to set out a process for incorporating negative publicity directly into project economics.

We started with an outline study of the effects of two high-profile incidents of negative publicity: Hoover's "Free Flights to America" promotion and the ill-fated launch of Unilever's manganese accelerator soap powder. The results showed two distinct outcomes: the effect on corporate image and the direct effect on a project, such as the launch of a new product. The next step was to identify a number of possible outcomes to an escalating scenario of negative publicity within the oil and gas sector. The economic consequences of each possible outcome are expressed as risk-assessed values (RAV's) that are the product of the probability and the cost of each outcome. To show this, we took a hypothetical case of handling of sour gas in a new field development and looked at the possible outcomes from four options for handling the gas: flaring, gas reinjection, power generation and seawater absorption.

The method developed in this paper outlines a process for quantifying stakeholder values and potential negative publicity in the planning stages of potentially sensitive projects. The process provides a logical and transparent framework that encourages the exploration of these softer issues. It is designed to provide indicative, rather than definitive, values to show whether the inclusion of risk-assessed costs would alter the decision on the basis of conventional economics. The process also provides a guide for developing a consistent basis for decision making, checks the sensitivity of the development option to negative publicity, and highlights the cost critical areas.
Eye Yoga for Glaucoma: Recovery of Vascular Dysregulation and Visual Field Loss - A Randomized Controlled Trial
Authors: Zhou Wanshu , Fricke Luisa , Sabel Bernhard A.
Published: November 2024

Purpose
Because stress can aggravate primary open angle glaucoma (POAG) progress, we studied if stress reduction by eye muscle exercises and meditation (Eye Yoga, EY) and can normalize VD, intraocular pressure (IOP) and visual field (VF) function as a complementary, personalized approach of eye care.
Patients and Methods:
POAG patients were randomized 1:1 to an EY (n = 15) or control group (n = 12). While EY was practiced daily for one hours for one month at home using an iPod-audio guide, control patients read daily relaxing books. Outcome criteria were IOP, retinal vessel dynamics and VF recovery.
Results
After intervention, EY patients, but not controls, showed a 6.4% IOP reduction (p = 0.027). This was associated with VF improvement (mean deviation) which were greater in EY than controls (p < 0.001). Furthermore, in EY, but not controls, pattern deviation recovered in VF regions where microvessel (third order-branch) vasoconstriction improved (artery: p = 0.012; vein: p = 0.042) and EY mean artery diameter recovered significantly (p = 0.015). When pooling data of both groups, recovered VF regions, but not non-recovered fields, showed significantly larger arterial diameter gains (2.4 [-0.3-5.3] MU). Neither treatment had any adverse events.
Conclusions
Because EY is able to reduce vasoconstriction and improve VF function in POAG confirms the hypothesis that mental stress is a contributing, or even key mechanism of POAG, and improved blood flow a fundamental mechanism of vision recovery and restoration. Daily eye yoga home-exercises are a safe and effective complementary PPPM method which can be easily adopted for POAG care.
Trial Registration clinicaltrials.gov (NCT04037384)
Door-to-Door Overdose Harm Reduction: an Illinois Case Study
Authors: Mason Maryann , Johnson Bruce , Johnston Sean , Alexander Ursula , Ajala Oyindamola , Andrews Nia , Welch Sarah B. , Schaffner Chris
Published: November 2024

Background
Harm reduction for people who use drugs (PWUD) is an established evidence-based practice that encompasses a wide variety of services, delivery formats, and settings and has been named a priority in US drug policy. Harm reduction is focused on planning with communities and meeting PWUD where they are and encompasses a wide variety of interventions. We describe and report the feasibility, acceptability, and processes implementation outcomes for an innovative pilot drug overdose harm reduction intervention, Block-by-Block (BXB), focused on training for and distribution of naloxone and test strips in areas identified as high risk for fatal overdoses.
Case presentation
Begun in 2020, BXB operates in five pilot sites in four Illinois counties. Through partnerships with local organizations, BXB delivers harm reduction services in a private setting (home) or in a setting not specifically targeting PWUD (businesses, libraries, faith-based organizations, etc.) to reach PWUD and their friends, family and neighbors living in areas disproportionately affected by opioid overdose death. The intervention theory is based on acknowledgement that harm reduction services that require PWUD to visit a mobile unit, van or community organization, may not reach those in need or their friends, neighbors, and family for a variety of reasons including stigma associated with drug use, lack of awareness about these services, or where to locate them. Services delivered include education and training in the use of naloxone and fentanyl, xylazine and benzodiazepine test strips. Leave behind materials include naloxone, test strips and handouts with information on the intervention and local resources.
Conclusions
Results to date indicate that this intervention is feasible –over half (55%) of the doors approached were answered. Acceptability of the intervention as delivered is high --people at 75% of doors that were answered were interested in and received training and/or supplies. BXB is flexible in that it has been quickly adapted to changes in community conditions, the drug supply, and shifting high risk areas as they developed. This is a promising intervention that leverages available data and resources and is readily implementable in communities with support from a central program administrator and access to geo-coded data.
Investigation of the plasma reaction behavior of a Coke Oven Gas with trace oxygen in a coaxial DBD reactor
Authors: Nitsche Tim , Lohmann Heiko , Budt Marcus
Published: November 2024

The presented study shows experimental results with literature comparison for understanding of the oxygen removal in coke oven gas (COG) with plasma. The reaction of oxygen with the main COG components H2, CH4, and CO are investigated as well as the occurrence of potential side reactions as the splitting of CO2 and CH4. Further potential side reactions in the COG mixture known from literature as hydrogenation reactions are discussed in contrast to the observations of the experiments.
Addressing the role of COVID-19 pandemic-induced Mental Health Problems on the Emergence of suicide among Pregnant Women, Egypt: A case-control study”
Authors: Said Mervat , Fouad Eman , Hassan Walid , Al-Fath Amr Mostafa  Kamel Abu , Khalil Yomna Ahmed
Published: November 2024

Background
Before the emergence of the Coronavirus disease (COVID-19) pandemic, the research reported that pregnancy is associated with increased suicide risk. However, data regarding the impact of COVID-19 on suicidal risk is not conclusive, and most of the studies are derived from Western countries. This study aimed to identify the suicidal risk and clinical correlates among pregnant women in Egypt during the COVID-19 crisis. A case-control study design was used in this study and included 245 pregnant women, and an equal number of non-pregnant women served as the control group. Pregnant participants were recruited from the Outpatient Departments (OPD) attending antenatal care services within the Obstetrics and Gynecology clinic at Zagazig University Hospital (ZUH) in Sharkia, Egypt. The control group consisted of non-pregnant relatives accompanying the pregnant participants. Data were collected through interviews using a semi-structured questionnaire to gather sociodemographic and clinical information, along with the administration of the following scales: Depression, Anxiety, and Stress Scale-21 (DASS-21), Fear of COVID-19 Scale (FCV-19S), Impact of Event Scale-Revised (IES-R), and Beck Scale for Suicide Ideation (BSS).
Results
It indicated that the pregnant group had higher levels of anxiety, depression, and stress compared to the control group. Moderate to severe symptoms of Post-Traumatic Stress Symptoms (PTSS) were found in 18.1% of the pregnant women, compared to 12.2% in the non-pregnant group. Additionally, the pregnant group had a significantly higher mean total score on the BSS. Predictive factors for suicidal tendencies in the pregnant group included living in urban areas, a family history of suicide, changes in the employment status of the participants or their spouses, PTSS, and experiencing inter-partner violence (IPV) during the COVID-19 pandemic.
Conclusion
The COVID-19 pandemic has significantly impacted the mental well-being of pregnant women and increased the risk of suicide. Experiencing changes in employment status, particularly the husband, PTSS, and exposure to IPV are the most significant predictors of suicide during the COVID-19 crisis.
Design and Synthetic Utility of New HAT Organocatalysts Derived from Commercially Available Diamines
Authors: Maruoka Keiji , Jia JingWen , Kato Terumasa
Published: November 2024

A series of hydrogen-atom transfer (HAT) organocatalysts were conveniently prepared from commercially available diamine compounds, and their utility in photoinduced HAT catalysis ability was investigated. The combination of these readily available HAT organocatalysts with the Fukuzumi photoredox catalyst enables efficient and site-selective C−H alkylation of various functionalized substrates ranging from simple hydrocarbons to complex molecules. The site-selective C–H alkylation of multifunctional molecules has also been demonstrated. Notably, the sequential one-pot photoinduced dialkylations of bifunctional substrates can be realized. Mechanistic studies suggested that the 1-naphthylmethyl moiety on one nitrogen atom of the diamine compounds plays a crucial role in the reaction by inducing the facile generation of a cationic aminium radical on the other nitrogen of the diamine as an active intermediate for the HAT process.
The Impact of the African Continental Free Trade Area (AfCFTA) on the Ethiopian Economy
Authors: Mengistu Simachew , Fan Cui , Feleke Weldetensay
Published: November 2024

Using a GEPPML model, this study evaluates the possible effects of the AfCFTA on Ethiopia's economy. With fewer trade obstacles between member nations, the AfCFTA—the largest free trade area in the world by population—aims to improve intra-African and global commerce and spur economic growth. Ethiopia hopes to benefit from the AfCFTA by having more trade options, as the country is mostly dependent on agricultural exports. The study models the full implementation of the AfCFTA in both conditional and full endowment scenarios. The results showed that, under the full endowment scenario, the full implementation of AfCFTA raised Ethiopia's real GDP by 2.512% and total exports by 1.137%, greatly above average gains among member nations.
The Role of Enterprise Resource Planning In Cloud Computing services dissemination''A field study in the Yemeni governmental communication sector''
Authors: al-baham mohammed abdullah nasser , al-sanafi abdullah abdullah
Published: November 2024

The research aimed to discover The Role of Enterprise Resource Planning In Cloud Computing services dissemination in Yemeni governmental communication sector. The research used the descriptive analytical approach and the questionnaire as the main tool for data collection. The research population was all employees who use Enterprise Resource Planning in Yemeni governmental communication sector represented by (General Corporation for Telecommunications and Yemeni International Telecommunications Company- tell-Yemen) (the headquarters). The research concluded that there is an important role for Enterprise Resource Planning with its dimensions in disseminate Cloud Computing services in Yemeni governmental communication sector. The research recommended that, it is necessary for Yemeni governmental communication sector to make more studies to understand the relationship between customer relationship management, and Cloud Computing services dissemination, also make clear strategic plan for the transformation to the Cloud Computing, define the goals, the tasks, the activities, the responsibilities, the necessary steps to achieve it.
Optimising LED Light Spectra for Enhanced Shoot and Root Growth in Green and Red Pakchoi (Brassica rapa var. chinensis)
Authors: Kassim Rosniza , Singh Ajit , Yap Joshua
Published: November 2024

Light quality is a critical factor influencing plant growth, particularly in controlled environments where artificial lighting, such as LED lights, is used. This study investigates the effects of different LED light spectra on the shoot and root development of green and red pakchoi (Brassica rapa var. chinensis). Specifically, the study examines the impact of various combinations of red, blue, and green wavelengths on key growth parameters, including plant height, plant width, leaf number, leaf area, and root morphology. The results demonstrate that red-dominant light (100R) significantly enhances shoot elongation and leaf expansion, whereas the red-blue light combination (82R18B) promotes more vigorous and extensive root systems. Notably, the 82R18B light treatment was found to provide the most balanced growth between shoots and roots, producing plants with robust morphology and strong root structures essential for nutrient and water uptake. The study concludes with a recommendation for using the 82R18B light formulation in commercial pakchoi cultivation, as it optimizes both shoot and root development, leading to higher quality and more marketable crops. These results emphasise the significance of adjusting light spectra to optimise plant growth and productivity in controlled environment settings.
Enhanced Chromium removal from water using ball milled nano-biochar derived from Eichhornia crassipes (Water hyacinth)
Authors: M Mohanadevi , K Dhanabalan
Published: November 2024

Hexavalent chromium (Cr (VI)) contamination in water sources poses a significant threat to human health and the environment due to its toxicity and carcinogenicity. In recent years, biochar-based adsorbents have gained attention for their potential to effectively remove heavy metals from water. This study focuses on the synthesis and application of ball-milled nano-Eichhornia (water hyacinth) biochar (BMNEBC) as an innovative adsorbent for the removal of Cr (VI) from aqueous solutions. In this research, Eichhornia plant leaves were utilized as the precursor for biochar production through a pyrolysis process. The produced biochar was subjected to physical modification (ball milling) to obtain nano-sized particles, thereby increasing the surface area and porosity of the material. Batch adsorption experiments were conducted to evaluate the Cr (VI) removal efficiency of BMBNBC under various operating conditions, including initial Cr (VI) concentration, adsorbent dosage, contact time, and pH. The equilibrium adsorption data were fitted to different isotherm and kinetic models to analyze the adsorption mechanism and kinetics. The results indicated that BMBNBC exhibited a high affinity for Cr (VI) adsorption, with a maximum adsorption capacity of 293.2 mg/optimal operating conditions determined to achieve maximum removal efficiency, and the adsorption process was found to follow the Langmuir isotherm and pseudo-second-order kinetic model, suggesting monolayer adsorption and chemisorption as the predominant mechanisms.
Hydrogel containing decellularized spinal cord tissue induces M2 polarization in macrophages
Authors: Santos Marcelo Garrido dos , Franca Fernanda Stapenhorst , Pessi Augusto Vargas , Turck Patrick , Scholl Juliete , klein Adriane Bello , Figueiro Fabricio , Peres Alessandra , Pranke Patricia
Published: November 2024

Study design
Basic cellular study.
Objectives
The use of biomaterials for regeneration is a promising approach in the tissue engineering field, but some materials can cause an inflammatory response when introduced into an organism. Macrophages play a central role in controlling inflammation, and when exposed to a stimuli, they polarize into a pro-inflammatory (M1) or anti-inflammatory (M2) phenotype. In this study, an evaluation was madeof macrophage polarization and inflammatory response when exposed to a hydrogel, used to produce a bioink, containing Decellularized Spinal Cord Tissue (DSCT) using RAW 264.7 macrophages.
Setting
Stem Cells Research Institute, Brazil.
Methods
Macrophages were exposed to the hydrogel for 24 hours. Cell viability was analyzed by MTT and Live/Dead assay. Flow cytometry was used to evaluate macrophage polarization and mitochondrial membrane potential. Cytokines, ROS (reactive oxygen species) production, sulfhydryl compounds and TBARS were quantified to assess inflammatory response. PC12 cells were exposed to macrophage conditioned medium and MTT was used to analyze cell viability.
Results
Although macrophage exposure to the hydrogel altered its metabolic activity, no cytotoxic effect nor oxidative damage was shown. Hydrogel induced an increase in IL-10 levels. The presence of DSCT in the biomaterial induced a decrease in CD45 and CD69 expression as well as an increase in CD206, a classic M2 marker, in comparison to the controls and the hydrogel without DSCT.
Conclusion
The hydrogel induced M2 polarization in the macrophages and a decrease in the inflammatory response. This biomaterial may be a suitable alternative for spinal cord regeneration after SCI.
Overlap Syndrome Involving Multiple Sclerosis and Kikuchi–Fujimoto Disease Following COVID-19 Vaccination: A Case Report
Authors: Liu Ruihua , Zhao Pengyue , Zhang Yunting , Li Yan , Duan Zhihui , Li Shao , Shang Dandan , Du Yanjiao
Published: November 2024

Background: Multiple sclerosis (MS) is an immune-mediated disorder of the central nervous system, while Kikuchi–Fujimoto disease (KFD) is a rare type of lymphadenitis. The overlap of MS with KFD following COVID-19 vaccination has not been previously reported.
Case presentation: A 23-year-old Asian woman presented with lymphadenopathy and diplopia following COVID-19 vaccination. A biopsy of the cervical lymph node confirmed KFD, while magnetic resonance imaging (MRI) revealed demyelinating lesions consistent with MS. The presence of cerebrospinal fluid (CSF)-specific oligoclonal bands met the criteria for dissemination in time. The final diagnosis was MS overlapping with KFD. The patient was treated with intravenous methylprednisolone and intravenous immunoglobulin followed by dimethyl fumarate capsules to prevent recurrence. Three years later, she experienced dizziness and diplopia again. Follow-up MRI of the brain revealed multiple abnormal signals in both the cortical and subcortical regions, with some areas showing partial enhancement, suggesting a relapse of MS. After administering another steroid pulse therapy, the disease-modifying therapy was switched to ofatumumab. Follow-up assessment demonstrated significant improvement in the patient’s dizziness and diplopia.
Conclusion: This case is the first to describe the occurrence of MS overlapping with KFD following COVID-19 vaccination. This case demonstrates that shared pathogenic mechanisms and common genetic susceptibilities may contribute to the simultaneous development of both conditions. Close monitoring is essential to exclude the potential presence of lymphoproliferative disorders and autoimmune diseases.
Palladium-Catalyzed Enantioselective β-Hydride Elimination for the Construction of Remote Stereocenters
Authors: Zi Weiwei , Sun Shaozi , Sun Shengnan
Published: November 2024

The β-H elimination is a crucial elementary step in transition-metal catalysis, but controlling the stereochemistry of this process has been underdeveloped. The limited works reported so far have only focused on creating axial chirality in allenes, and no report has been able to build central chirality using asymmetric β-H elimination. In this study, we report a Trost ligand-enabled enantioselective desymmetric β-H elimination reaction from π-allyl-Pd. This transformation provides rapid access to cyclohexenes bearing a C4-remoted stereocenter, and total synthesis of (-)-oleuropeic acid and (-)-7-hydroxylterpineol was demonstrated. Computational studies have shown that the β-H elimination is the rate-determining step, and the non-covalent interactions between the amide moiety of the Trost ligand and the benzene and cyclohexane moieties of the substrate play a key role in stereocontrol during the β-H elimination.
Social Capital and Health-Related Quality of Life among Primary Health Care physicians: The mediating role of health-related behaviors
Authors: Wu Zonghao , Gu Zhuoqi , Wei Yukun , Huang Yuankai , Wang Ennan
Published: November 2024

Background
This study aimed to evaluate the correlation between social capital and physicians' health-related quality of life(HRQoL) in primary health care institutions. Simultaneously, we will examine the mediating role of health-related behaviors in the process.
Methods
Data was obtained from a nationwide cross-sectional survey conducted in 2021. Sociodemographic characteristics and health-related behaviors were collected by a self-administered questionnaire. We used the social capital of healthcare organizations reported by employees (SOCAPO-E) scale to measure the social capital and the EuroQol-five dimension-five level (EQ-5D-5L) to measure physicians’ HRQoL. The Tobit model was performed to evaluate the association between social capital and HRQoL. A bootstrap approach was used to assess the mediating effect of health-related behaviors.
Results
The results showed that social capital (β = 0.056, p<0.001) was significantly and positively associated with physicians' HRQoL. Health-related behaviors moderately mediated the relationship between social capital and HRQoL (BootSE = 0.0007, BootCI=[0.0005,0.0032]). In addition, the regression analysis revealed that sex, age, residence, employment form, and chronic diseases were also significantly associated with physicians' HRQoL.
Conclusion
Social capital not only directly affected physicians' HRQoL, but also indirectly affected HRQoL through health-related behaviors. Our findings suggested that investing in social capital may serve as an effective strategy for enhancing physicians' occupational health.
The Dynamic Preparedness Metric: results from a multi-country analysis of health emergency preparedness
Authors: Vernaccini Luca Marco , Bell Cynthia , Gribble Rebecca , Nguni Robert , Samhouri Dalia , Chamla Dick , Talisuna Ambrose , Perehinets Ihor , Nguyen Phuoung Nam , Samuel Reuben , Rocque Stephane de La , Xing Jun , Chungong Stella , Kandel Nirmal
Published: November 2024

Background
The COVID-19 pandemic has underscored limitations in current methods for assessing country-level health emergency preparedness, which often overlook essential factors like ongoing epidemics, natural disasters, conflicts, or community trust. Addressing this, the World Health Organization (WHO) developed the Dynamic Preparedness Metric (DPM), a composite measure that assesses preparedness by accounting for hazards, vulnerabilities, and key risk factors, offering insights for improving country-level capacities.
Methods
Our analysis tested the DPM’s effectiveness in supporting preparedness at global, regional, and national levels, focusing on five acute syndromes. The DPM regional average is calculated from individual country scores, and a one-year trend analysis (from the 1st to 4th quarters of 2023) was conducted globally for all syndromes, and regionally for respiratory syndromes. Additionally, we back-calculated DPM scores from 2018 to 2021 to explore its responsiveness to the COVID-19 pandemic. Underlying standardized indicators were also analysed to pinpoint primary risk factors.
Results
Initial findings highlight substantial variation across countries and WHO regions. Short-term analyses revealed temporal trends in regional risk, while medium-term analyses showed decreased scores and expanded capacity gaps during COVID-19. Primary risk factors identified include health system deficiencies, urbanization, and the prevalence of epidemic-prone diseases, with considerable regional differences.
Conclusions
These results emphasize the importance of a dynamic, risk-informed approach to preparedness assessment. Tracking shifts in hazards, vulnerabilities, and capacities enables countries to refine emergency preparedness and readiness planning, fostering more responsive and effective health security strategies.
Transcriptome Profiling of Eggplant root Under Salt Stress
Authors: Sun Hongmei , Wang Yong , Cao Lianbin , Song Li , Jiang Jun , Li Yan , Zhao Hongxing , Cao Meng , Tian Shilin
Published: November 2024

Background Roots are the initial organs to perceive and adaptively adjust when confronted with salt stress. However, the mechanisms underlying salt stress tolerance in the roots of eggplant remained elusive. We performed transcriptome sequencing on the roots of eggplant under 150 mM NaCl treatment.
Results The results indicated that a total of 3491 differentially expressed genes (DEGs) were identified. Gene Ontology analysis revealed that oxidoreductase activity, catalytic activity, and microtubule-based process were the most enriched terms among the DEGs. Kyoto Encyclopedia of Genes and Genomes analysis revealed that Pentose and glucuronate interconversions and Phenylpropanoid biosynthesis pathways were the most enriched pathways among the DEGs. A pectinesterase (PME)-associated PMEs/PMEIs module may positively participate in the salt tolerance.
Conclusions Taken together, this study provided candidate genes linked to salt tolerance in eggplant roots, offering a foundation for further in-depth study of resistance mechanisms and supporting the development of novel salt-tolerant eggplant varieties with genetic resources and technologies.
R3D: an approach combining cost-sensitive and insensitive classifiers to achieve more balanced scores
Authors: Lima Helton Souza , Fernandes Damires Yluska de Souza , Moura Thiago José Marques
Published: November 2024

Cost-sensitive classifiers have demonstrated to be more cost-effective than traditional classifiers in many real-world classification problems by avoiding high amounts of money loss. This is usually measured by a savings score. On the other hand, these classifiers present, in some cases, a reduction on conventional performance scores such as accuracy, f-score, precision and recall rates. Government applications are included in this segment of problems but, on public domains, the pursuit to the lowest cost is not an exclusive priority. In this light, this work proposes an approach which uses traditional and example-dependent cost-sensitive supervised learning in order to classify requests for revision of a Brazilian tax administration service. This hybrid approach has achieved a better trade-off when considering cost savings, accuracy, f-score, precision and recall in accordance to the business and data rules.
The effects of inhibiting IRE1α on the proliferation of ovarian granulosa cells
Authors: Li Chao , Tan Yong-Peng , Meng Tie-Gang , Gao Di , Xu Ke , Lu You-Hui , Yi Li-Tao , Liu Shu-Chen , wang Guang , Sun Qing-Yuan , Lei Xiao-Can
Published: November 2024

IRE1α, a type I transmembrane protein characterized by a cytoplasmic serine/threonine kinase domain, is related to ER stress and ER function maintenance. In this study, 4µ8c, a highly effective selective inhibitor of IRE1α RNase, and APY29, an ATP competitive inhibitor, inhibiting IRE1α autophosphorylation and the kinase domain, were employed to elucidate the function of IRE1α on the proliferation of ovarian granulosa cells, with the ultimate goal of identifying novel strategies and methodologies for the prevention and treatment of associated diseases. Human ovarian granulosa cells (SVOG) cultured in vitro were treated with the IRE1α inhibitors 4µ8c and APY29. It was shown that inhibition of IRE1α reduced the cell ability of dealing with misfolded protein, triggered oxidative stress, altered mitochondrial membrane potential, and inflicted DNA damage, eventually lead to ovarian granulosa cell apoptosis.