bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH BESARNYA PEMBERIAN REWARD TERHADAP KINERJA DAN MOTIVASI KARYAWAN MBOK LAUNDRY DI KOTA PONTIANAK
Authors: Juhelti Juhelti
Published: January 2024

Penelitian ini memiliki tujuan untuk menganalisis dan mengetahui: Pengaruh besarnya pemberian reward terhadap kinerja karyawan Mbok Laundry di Kota Pontianak, Pengaruh besarnya pemberian reward terhadap motivasi karyawan Mbok Laundry di Kota Pontianak,  Pengaruh besarnya pemberian reward terhadap kinerja dan motivasi karyawan Mbok Laundry di Kota Pontianak. Metode yang digunakan dalam penelitian ini menggunakan pendekatan kuantitatif dengan metode penelitian deskriptif. Teknik pengumpulan data pada penelitian ini menggunakan angket atau kuesioner yang disebarkan pada karyawan Mbok Laundry di Kota Pontianak. Populasi dan sampel dalam penelitian ini adalah seluruh karyawan Mbok Laundry yang berjumlah 30 orang. Data tersebut diolah dengan menggunakan SPSS 23. Analisis data yang dilakukan dalam penelitian ini ialah dengan uji validitas, uji realibilitas, uji asumsi klasik, regresi linear sederhana serta regresi linear berganda. Hasil dari penelitian menunjukkan bahwa: besarnya pemberian reward berpengaruh secara signifikan terhadap kinerja karyawan, besarnya pemberian reward tidak berpengaruh secara signifikan terhadap motivasi karyawan, besarnya pemberian reward tidak berpengaruh secara signifikan terhadap kinerja dan motivasi karyawan.
Realidad virtual y metaversos como canal e inspiración de fashion films. Branded content inmersivo y moda
Authors: Martin-Ramallal Pablo , Ruiz-Mondaza Mercedes
Published: January 2024

Los fashion films (FF.FF.) son una herramienta vital en la promoción de la moda, los cuales se aprovechan de las nuevas tecnologías. Este estudio examina la influencia de la realidad virtual (RV) y los metaversos en el branded content de moda, enfocándose en su capacidad para inspirar y crear inmersión. La investigación adopta un enfoque deductivo utilizando un estudio de caso para evaluar la influencia de la RV y los metaversos en esta estrategia de marketing. Se recurrió a 116 profesionales y expertos del sector, los cuales fueron sometidos a un cuestionario Likert. Como resultado, se observa que los FF.FF. inspirados, proyectados o fundamentados en RV tienen la capacidad de sortear barreras de comunicación y son bien recibidos por el público versado en moda. Se resalta el potencial de la RV y los metaversos, especialmente en términos de narrativa, promoción y experiencias de marca. Aunque algunos aspectos de la inmersión esférica, como los videos 360º, se ven en declive, los formatos innovadores, como las metazines y los festivales metaversales, generan un interés. A pesar de las opiniones variadas, la mayoría de los heurísticos ven estas tecnologías como una fuente inspiradora
Lenguajes visuales en la Era del Desarrollo
Authors: Hernández Quiñones Óscar Daniel
Published: January 2024

A partir de fuentes primarias acopiadas en archivos de las agencias especializadas de la Organización de Naciones Unidas (ONU), el artículo explora la vinculación del cine educativo y la fotografía documental al programa global de comunicaciones con el que estas difundieron su modelo de desarrollo y asistencia técnica en la segunda posguerra. Aunque ambas expresiones fueron valoradas positivamente por sus alcances masivos, la integración de cada una al engranaje institucional de las agencias sorteó vicisitudes particulares que merece la pena tematizar, pues revelan la capacidad adaptativa del discurso desarrollista y del multilateralismo a agitaciones del periodo como la Guerra Fría y los procesos de descolonización en el Sur Global.
Cinco ejercicios de pensamiento educativo
Authors: De los Santos Marín Alejandro
Published: January 2024

Esta es una reseña del libro Cinco ejercicios de pensamiento educativo, un ensayo filosófico que exige un despertar para los profesionales de la educación con respecto a la percepción de la realidad educativa, y más en concreto de la escuela. A través de la lectura, el libro se ayuda de distintos aspectos éticos, antropológicos y filosóficos para invitar al lector a crear un pensamiento liberado a partir de la lectura, la escritura, la contemplación, la atención y la caricia pedagógica. Todo ello para hacer frente a las exigencias capitalistas que homogeneizan un modelo de escuela que frena las afecciones del mundo y las relaciones humanas, con el fin de dotar de sentido a la educación.
Production and nTopology optimization of an additive manufactured support for smart glasses
Authors: Nunes Francisca , Trindade Mariana , Costa Jose
Published: January 2024

The fast development of Additive Manufacturing (AM) technology over the past few decades has been remarkable, and it is expected that this development will continue. This technology has benefits over conventional production techniques, such as its flexibility, dependability, energy usage, and material efficiency. The subject of this article is the design and optimization of support for smart glasses based on a Vuzix model using nTopology and Fusion 360. The whole process of creating the support evolves from selecting the appropriate material (Onyx) and AM process to this type of component (Fused Filament Fabrication), to adjusting the CAD model of the glasses, using Fusion360 to create the initial design of the support, and nTopology to optimize the model. A static analysis simulation was also performed to validate the different models made.
A Prospective on Vagal Tone via Auricular Stimulation and Deep Breathing
Authors:   University Of California, Chopra Deepak
Published: January 2024

The vagal nerve, or the tenth cranial nerve, is a paramount component of the autonomic nervous system, playing a pivotal role in the regulation of various bodily functions
Global Importance of Arboviruse, Sandfly Fever (Pappataci Fevre, Three-Days fever, Phlebotomus Fever)
Authors:   Tehran University Of Medical Sciences, Vatandoost Hassan
Published: January 2024

Sandflies are vectors of different types of Leishmaniasis (Protozoa),Sandfly fever (virus) and Bartenollosis (Carrion’s disease) (Bacteria). Sandfly fever (Pappataci fevre, Three-days fever, Phlebotomus Fever) is one of the arbovirus disease which can be transmitted via sand fly bite and transmission. Many serotypes of virus as sand fly fever have been reported so far.
Relación bilateral entre Colombia y Estados Unidos durante el siglo XXI
Authors: Andrade-Quiroga Jorge Eliecer
Published: January 2024

El presente artículo elabora un estado del arte de la relación bilateral entre Colombia y Estados Unidos durante el siglo XXI, tomando en cuenta factores y conceptos que se involucran con el tema, tales como el Plan Colombia, la lucha contra las drogas, el narcotráfico y la injerencia que ha presentado la relación en materia de política exterior en Colombia. Se realizó el trabajo mediante una investigación cualitativa, con diseño de investigación documental y alcance descriptivo-analítico. A través del análisis de la información obtenida, se hallaron posiciones tanto a favor como en contra de la relación y estrategias entre ambos países y, por otro lado, múltiples comentarios y recomendaciones que hacen los autores con la intención de aportar soluciones a través del proceso investigativo. La información recopilada da cuenta del escenario complejo que representa la relación colombo-estadounidense, la cual debe revisarse en aras de que sus resultados futuros puedan alcanzar un carácter más social.
Faktor Internal dan Eksternal dan Strategi Pengembangan Agribisnis Porang (Studi kasus PT. Al-Fatih Porang Indonesia)
Authors: FM A. Syahrul Ramadhan , Salengke Salengke , Mahyuddin Mahyuddin , Anita Andi Suci
Published: January 2024

Porang (Amorphophallus muelleri Blume) is one type of tuber plant that is starting to be widely produced in Indonesia because it has high economic value. This is because porang is widely used in the food, health, cosmetic, and manufacturing industries. Over the last decade, the export volume has increased drastically. In 2020, the export value of Indonesian porang was dominated by Thailand with a market share of 59.3%, followed by China with a total of 130 shipments, or 47.84% of total porang exports. Export share to Thailand and Australia increased significantly in 2020, with an increase of 920.1% and 526.7%, respectively. The purpose of the study was to determine the internal and external factors that affect the development of porang and obtain strategies for porang development at PT Al-Fatih Porang Indonesia. Qualitative descriptive research with Porter's Diamond Theory to determine the competitive position of porang agribusiness and SWOT analysis to determine the internal and external factors of porang agribusiness at PT Al-Fatih Porang Indonesia The results of Porter's Diamond Theory analysis showed that in PT Al-fatih Porang Indonesia's conduct of porang agribusiness development, each subsystem has not been mutually supportive and related to each other. This can be seen in the marketing and agribusiness subsystem, which is still difficult. The appropriate strategy for the development of porang at PT. Al-Fatih Porang Indonesia is to optimise the utilisation of porang.
Analisis Faktor-faktor yang Memengaruhi Volume Ekspor Kopra Indonesia Di Pasar Dunia
Authors: Dalimunthe Apip Gunaldi , Sibuea Faiz Ahmad , Hernosa Siswa Panjang
Published: January 2024

Kopra diekspor karena jumlah produksi tinggi. Namun jumlah produksinya tidak seimbang dengan volume ekspor kopra sehingga perlu daya saing ekspor kopra Indonesia di pasar dunia. Metode penelitian kuantitatif dan deskriptif. Daya saing ekspor kopra metode Revealed Comparative Advantage (RCA) dan Export Product Dynamic (EPD). Hasil penelitian perhitungan RCA (Revealed Comparative Advantage) ekspor kopra Indonesia ke Bangladesh, Filipina, dan Myanmar memiliki keunggulan komparatif nilai RCA rata-rata di atas 1. Sedangkan 4 negara tujuan ekspor kopra ke India, Pakistan, Malaysia, dan China memiliki nilai RCA di bawah 1 sehingga tidak komparatif. Perhitungan EPD (Export Product Dynamic) ekspor kopra Indonesia ke Bangladesh selama 5 tahun terakhir Falling star, Rsing star, Rising star, Rising star, dan Rising star. Nilai EPD (Export Product Dynamic) ekspor kopra Indonesia ke India selama 5 tahun terakhir posisi Falling star, Retreat, Falling star, dan Lost opportunity. Nilai EPD (Export Product Dynamic) ekspor kopra Indonesia ke Pakistan selama 5 tahun terakhir posisi Lost opportunity, Rising star, Falling star, Rising star, dan Lost opportunity. Nilai EPD ekspor kopra Indonesia ke Malaysia selama 5 tahun terakhir posisi Retreat, Rising star, Falling star, Retreat, Lost opportunity. Nilai EPD ekspor kopra Indonesia ke Filipina selama 5 tahun, hilangnya peluang, retreat, rising star, falling star, dan retreat. Nilai EPD ekspor kopra Indonesia ke China selama 5 tahun terakhir hilangnya peluang, rising star, rising star, rising star, dan lost oppurtunity. Nilai EPD ekspor kopra Indonesia ke Myanmar selama 5 tahun terakhir rising star, falling star, rising star, rising star, dan retreat.
Keragaan Usahatani dan Kinerja Agribisnis Jagung di Kabupaten Ciamis
Authors: Kurnia Rian , Andrie Benidzar M , Aziz Saepul
Published: January 2024

Corn productivity in West Java continues to decline from year to year. This is inversely proportional to the need for corn which increases from year to year. This research aims to assess the performance of agribusiness subsystems in sustainable corn agribusiness in Ciamis Regency. The performance of corn agribusiness development is explained using descriptive analysis and processed by grouping using percentages and then given a narrative explanation to provide an empirical picture of the primary data collected from respondents. The performance status of maize agribusiness development is discussed using an agribusiness system approach consisting of production input subsystem, production/on-farm subsystem, handling and processing subsystem, marketing subsystem and supporting facilities subsystem. Based on the results of the analysis of the performance of the corn agribusiness system in Ciamis Regency, it is in the good category (more than 60 percent). So it can be said that corn farmers in Ciamis Regency have implemented the corn agribusiness system well. This means that with good agribusiness performance, the development of corn in Ciamis Regency has the potential to continue to be developed in order to achieve corn self-sufficiency as proclaimed by the government. Only the performance of the supporting subsystem is in the sufficient category (less than 60 percent). This is because there are still many farmers who have not benefited from climate mitigation policies and access to financial institutions. Agribusiness performance is closely related to productivity because it is an indicator in determining how efforts to achieve high productivity in a farming business. In connection with this matter, the effort to conduct an assessment of the performance of agribusiness in the development of farming is important.
Faktor-Faktor yang Memengaruhi Keputusan Pembelian Minyak Goreng Kemasan Bermerek di Kota Bandung
Authors: Singgih Saskia Firmani , Utami Hesty Nurul
Published: January 2024

Consumer behavior influences the purchase decision-making process. The consumer decision process in buying branded packaged cooking oil products will be decided by various things, including product attributes. The purpose of this study is to see how much influence product attributes (brand, product quality, and price) on consumer decisions in buying branded packaged cooking oil in Bandung City. This study uses a quantitative research design with survey methods conducted in three sub-districts, namely Buah Batu District, Babakan Ciparay District, and Bandung Kulon District. The analysis used is descriptive analysis and inferential analysis consisting of regression analysis, T test, and F test. The results showed that product attributes which include brand variables, product quality, and price were only product quality variables that had a negative effect or hypotheses were rejected against purchasing decisions, while brand and price variables had a positive effect. This shows that the majority of consumers making purchases do not make quality the main goal. Consumers make purchases as an obligation to meet basic needs.
Asystentura rodzinna jako profesjonalny wymiar wsparcia współczesnych rodzin
Authors: Sordyl-Lipnicka Barbara , Czechowska-Bieluga Marta
Published: January 2024

Celem niniejszego opracowania była prezentacja i analiza narracji asystentek rodzin na temat ich funkcjonowania zawodowego, stanowiąca egzemplifikację zaprezentowanych wyników dotychczasowych badań. Zastosowano metodę studium przypadku. Próbowano dotrzeć do edukacyjnych wątków doświadczeń z pracy pięciu asystentek rodzin.

Asystentura, w prezentowanych analizach jawi się jako praca ukierunkowana na wprowadzanie zmian w życiu rodzin, których członkowie traktowani są jako partnerzy lub klienci, a zdecydowanie rzadziej postrzegani są jako przyjaciele. W rozwoju kompetencji zawodowych badanych przejawia się pewna przypadkowość niż zaplanowana działalność edukacyjna oraz widoczna jest niedostatecznie rozpowszechniona systematyczna superwizja. Negatywny kontekst wyników badań odnosi się do przypisywania przyczyn niepowodzeń niewłaściwym postawom członków rodzin, ograniczonej refleksji nad własnym działaniem oraz braku poczucia wchodzenia w skład zespołu specjalistów pracujących z rodziną.
Implementasi Convolutional Neural Network Pada Robot Tikus Micromouse Untuk Navigasi Labirin Dengan Pendeteksi Garis Menggunakan Raspberry Pi
Authors: Pangestu Devin , Rippun Gideon Manalu Ferry
Published: January 2024

Micromouse is a science and technology project competition that began in the late 1970s. Simply put, the micromouse competition is an event where robotic mice can navigate a 16x16 maze without human assistance. Convolutional Neural Network, also known as CNN, is an extension of the Artificial Neural Network (ANN) designed to process two-dimensional data and is often used for classification, recognition, and prediction tasks. In the conducted research, a robotic mouse was designed using Raspberry Pi to control servo motor movements and utilize a camera to detect maze obstacles, such as intersections, through image scanning. The robotic mouse was tested using a CNN architecture model on TensorFlow, assisted by a line detection algorithm. The testing results indicated that the CNN model architecture showed signs of overfitting (the model learned features too well from the training data) with an accuracy of 96.53%, and the model accuracy evaluation result was 97.97% on the designed dataset. As part of the testing, a maze size of 5x5 was used. The testing of the Convolutional Neural Network model and line detection algorithm, when applied to the robotic mouse, demonstrated that the mouse could navigate according to the path. However, the recorded data was influenced by external light reflecting off the surface of the path, causing the line detection algorithm to perceive it as an obstacle, leading the robot to turn back..
Klasifikasi Gender Berdasarkan Gambar Menggunakan Metode Deep Learning Pada MATLAB
Authors: Sachi Haenuki , Wijayanti Linda , Octaviani Sandra
Published: January 2024

In the present era, machine intelligence, also known as Artificial Intelligence (AI), is demanded not only to execute specific commands but also to recognize, analyze, or even make decisions, thereby providing desired outputs. By harnessing the power of AI, it is anticipated that desired outcomes will be more accurate and goal achievement will be optimized, minimizing losses. With the capabilities of AI in mind, a research study has been conducted on AI's ability to analyze and make decisions based on specific data. In this study, data in the form of images of men and women were utilized. The objective of this research is to analyze the ability of AI, particularly in gender classification. The method employed in designing this system is Deep Learning, with GoogLeNet as the Convolutional Neural Network utilized. In testing, the data accuracy ranged from 61.8% to 100% for the system without training algorithm options and from 97.5% to 100% for the system with training algorithm options. Testing was also carried out on a smaller set of training data and grayscale images, yielding lower accuracy ranges. From this research, it can be concluded that the quantity of training data, image preprocessing, and training algorithm options are crucial indicators for enhancing prediction accuracy.
Tourism Industry Supply Chain through Stakeholder Participants: Facing Environment Uncertainty of Post Pandemic Covid-19
Authors: Achmad Fandi , Sriwana Iphov Kumala , Prambudia Yudha , Rumanti Augustina Asih
Published: January 2024

The environmental uncertainty due to the COVID-19 pandemic poses severe challenges for all parts of the supply chain in the tourism industry. The focus of the Indonesian government is to improve the condition of the tourism industry, which has experienced a decline in the number of tourists due to the COVID-19 pandemic. A supply chain tourism industry framework was developed through the Support System Facilities (SSF) variable to map the actors in the tourism industry activities in an uncertain environment due to COVID-19. The method in this study uses a qualitative descriptive approach through in-depth interviews, direct observation, and literature study. The results of this study are the tourism industry supply chain conceptual framework which states that there are several stages in distributing services and support systems and facilities to tourists, namely through suppliers, tour operators, tour agencies, and tourists. This finding has practical implications for the government in making a policy strategy.
Penjadwalan staf PT. Adi Sarana Logistik Divisi Outbound Unit Picker dan Dispatcher berdasarkan Minimisasi Jam lembur
Authors: Silalahi Agustinus , Heryanto Timotius , Hidayat Trifenaus Prabu , Hutahaean Hotma Antoni , Indriati Kumala
Published: January 2024

PT. Adi Sarana Logistik (PT ASL) is a company engaged in the warehouse and logistics sector, which delivers many packages daily. Previously, manual scheduling took a long time, and there were violations of working hours regulations. The research was conducted at the outbound division, in picker and dispatcher units for leaders and operational staff, where the number of operational staff varies each month, so there are four schedules were produced where this study aims to minimize overtime hours for each level of staffs and units by Goal Programming and Binary Integer Programming which are completed with LINGO 18.0. The results of this study have been implemented in the company, where the schedule only takes a few seconds, while previously, it took 1-2 days. The scheduling carried out in this study is in October 2022, where all employees for leaders and staff in each unit have 22 working days, nine days off, 1 hour of overtime, and follow the rules.
Nutritional Status and Factors Affecting Food Intake among Hospitalized Patients in Hospital Ampang
Authors: Mohd Nasir Siti Anissa , Shaharuddin Izyan Faiqah , Ismail Nazrul Hadi , Zaman Mazuin Kamarul , Rasimun Siti Ramlah Rasimun
Published: January 2024

The study aims to measure the current nutritional status and factors contributing to food consumption during hospitalization at Hospital Ampang. This is a cross-sectional study of 206 patients consisting of 104 males and 102 females respectively between 18 to 70 years of age. Data obtained from Factors Influencing Dietary Intake of Hospitalized Patients Questionnaire and Nutritional Risk Screening (NRS 2002). We used standardized methods to measure weight, height. Body weight categories were defined based on Body Mass Index (BMI). The BMI of participants was 26.08±4.56 kgm-2 and 52.0% (107) of participants had low risk of malnutrition and at risk of malnutrition. 85.4% admitted that the food tasted different. To conclude, patients’ low consumption of food during hospitalization should be enhanced. Thus, it is essential to implement effective strategies and interventions to increase dietary intake among hospitalized patients to fulfill their nutritional requirements and encourage quick recovery.
Deriving Sunnatic Codes In Abrahamic Hospitality For Hospitable Event
Authors: Fatah Yasin Muhammad Dhiya'ul Hafidh , Fatah Yasin Raudlotul Firdaus , Fatah Yasin Muhammad ‎Muthi’ul Haqq
Published: January 2024

Al-Qur’an memerintahkan Nabi Muhammad SAW untuk menyampaikan kisah keramahtamahan Nabi Ibrahim (Abraham) kepada orang-orang beriman, yang menekankan pentingnya bagi mereka untuk merenungkan kisah tersebut dan mengambil pelajaran yang relevan darinya. Oleh karena itu, penelitian ini bertujuan untuk mengidentifikasi pelajaran-pelajaran tersebut dan merancang aturan Sunnah yang dapat diterapkan pada acara ramah tamah. Dengan menggunakan metode tafsir tematik, penelitian ini mengkaji secara mendalam Al-Qur’an untuk memilah ayat-ayat yang relevan dengan topik yang bersangkutan dan menguraikannya lebih lanjut dengan dukungan hadis Nabi dan tafsir keilmuan. Studi ini menemukan bahwa kisah keramahtamahan Ibrahim diulang tiga kali di seluruh Al-Qur'an, semakin penting dan saling terkait informasi yang harus ditiru oleh orang-orang beriman dan penganutnya. Beberapa kata yang digunakan dalam kisah tersebut memuat panduan khusus yang berkaitan dengan sambutan ramah seperti salam yang melambangkan sapaan terbaik; yang dimaksud Ibrahim dan istrinya adalah penyambutan oleh pemilik atau tuan rumah; menunggu yang berarti tidak terburu-buru; betis menandakan bahan makanan lokal; lemak berarti bahan makanan berkualitas; hanidh berarti hidangan cepat saji namun tetap estetis; sambil menunjukkan kehati-hatian berarti jujur dalam mengungkapkan emosi.
The Western Concept of Religion seen through Asian Alternatives
Authors: Schlieter Jens
Published: January 2024

In this contribution, I discuss under the heading “inversed hermeneutics” a process wherein the conceptual, classificatory terms of a foreign knowledge system are used to interpret one’s own concepts and their underlying assumptions. A key function of “inversed hermeneutics” is to induce a deliberate alienation and thus momentarily placing the cognizing subject into a liminal state of “unfamiliarity.” This method should help to introduce and probe new ways of classifying things.
[68Ga]Ga-THP-Tetrazine for bioorthogonal click radiolabelling: Pretargeted PET imaging of liposomal nanomedicines
Authors: Mishra Aishwarya , Carrascal-Miniño Amaia , Kim Jana , T. M. de Rosales Rafael
Published: January 2024

Pretargeted PET imaging using bioorthogonal chemistry is a leading strategy for the tracking of long-circulating agents such as antibodies and nanoparticle-drug delivery systems with short-lived isotopes. Here, we report the synthesis, characterisation and in vitro/vivo evaluation of a new 68Ga-based radiotracer [68Ga]Ga-THP-Tetrazine ([68Ga]Ga-THP-Tz) for bioorthogonal click radiochemistry and in vivo labelling of agents with slow pharmacokinetics. THP-tetrazine (THP-Tz) can be radiolabelled to give [68/67Ga]Ga-THP-Tz at room temperature in less than 15 minutes with excellent radiochemical stability in vitro and in vivo. [68Ga]Ga-THP-Tz was tested in vitro and in vivo for pretargeted imaging of stealth PEGylated liposomes, chosen as a leading clinically-approved platform of nanoparticle-based drug delivery, and for their known long-circulating properties. To achieve this, PEGylated liposomes were functionalised with a synthesised transcyclooctene (TCO) modified phospholipid. Radiolabelling of TCO-PEG-liposomes with [68/67Ga]Ga-THP-Tz was demonstrated in vitro in human serum, and in vivo using both healthy mice and in a syngeneic cancer murine model (WEHI-164 fibrosarcoma). Interestingly in vivo data revealed that [68Ga]Ga-THP-Tz was able to in vivo radiolabel liposomes present in the liver and spleen, and not those in the blood pool or in the tumour. Overall, these results demonstrate the potential of [68Ga]Ga-THP-Tz for pretargeted imaging/therapy but also some unexpected limitations of this system.
Liposomes to cubosomes: The evolution of lipidic nanocarriers and their cutting-edge biomedical applications
Authors: Attri Nishtha , Das Swarnali , Banerjee Jhimli , Shamsuddin Shazana H. , Kumar Dash Sandeep , PRAMANIK ARINDAM
Published: January 2024

Lipidic nanoparticles have undergone extensive research towards the exploration of their diversely ranging therapeutic applications. Although several liposomal formulations are in the clinics (e.g., DOXIL) for cancer therapy there are many challenges associated with the traditional liposomes. To address these issues, modifications in liposomal structure and further functionalization are desirable, leading to the emergence of solid lipid nanoparticles and the more recent liquid lipid nanoparticles. In this context, ‘cubosomes’, third-generation lipidic nanocarriers, have attracted significant attention due to their numerous advantages, including their porous structure, structural adaptability, high encapsulation efficiency resulting from their extensive internal surface area, enhanced stability, and biocompatibility. Cubosomes offer the potential for both enhanced cellular uptake and controlled release of encapsulated payloads. Beyond cancer therapy, cubosomes have demonstrated effectiveness in wound healing, antibacterial treatments, and various dermatological applications. In the article, the authors provide an overview of the evolution of lipidic nanocarriers, spanning from conventional liposomes to solid lipid nanoparticles, with a special emphasis on the development and applications of cubosomes. Additionally, it delves into recent applications and pre-clinical trials associated with cubosome formulations, which could be of significant interest to readers from backgrounds in nanomedicine and clinicians.
Las imágenes como recurso fundamental de la información durante la covid-19 y la fase de vacunación en medios digitales españoles
Authors: Peñafiel-Saiz Carmen , Morales-i-Gras Jordi , Echegaray-Eizaguirre Lázaro
Published: January 2024

El estudio tiene como objetivo caracterizar las imágenes que acompañan a las informaciones de la pandemia de la covid-19, la vacunación y los tratamientos contra el coronavirus en los medios de comunicación digitales: ABC, Deia, EITB.eus, El Correo, elDiario.es, El Mundo, La Razón, La Vanguardia, Naiz y Público (2020-2022). Se ha trabajado con una muestra de 15.654 imágenes únicas, sobre las que se ha procedido a identificar 15 clústeres con técnicas de Inteligencia Artificial, entre las que consta el algoritmo Inception V3ylas incrustaciones en espacios vectoriales o embeddings. Se opta por una estrategia no supervisada, propias de investigaciones de corte exploratorio e inductivo. Entre los resultados destaca la identificación de distintas tipologías de imágenes utilizadas por los medios de orientación médica y sanitaria, representaciones de la muerte y del drama humano causado por la pandemia, vinculadas a la dimensión más política y económica de la campaña de vacunación. Las imágenes analizadas forman parte de la ‘comunicación política’: un modelo de comunicación que busca y refuerza la relación entre el gobierno y los medios de comunicación, y viceversa, para generar confianza en la gestión y en el propio sistema. La diversidad de enfoques observada es un valor positivo ya que contribuye a establecer una realidad social operativa más poliédrica y rica. Los medios muestran diferentes preferencias a la hora de representar visualmente los temas, lo que se traduce en una distribución desigual de los mismos. El estudio ha identificado las diferentes narrativas revelando diferentes usos de imágenes cargadas emocionalmente que plantean un escenario complejo.
Sharenting en Instagram: abuso de la presencia del menor en publicidad
Authors: Fernández Blanco Elena , Ramos Gutiérrez Mercedes
Published: January 2024

La exposición de menores en redes sociales por parte de madres y padres influencers se está convirtiendo en una práctica demasiado habitual, especialmente en Instagram. El sharenting (share + parenting) entendido como compartición de información y fotos de los hijos en las redes sociales plantea numerosos interrogantes en el plano ético, legal y también publicitario. La huella digital de menores y sus posibles efectos se unen a la práctica de progenitores influencers que emplean la imagen de sus hijos para promocionar marcas de productos y servicios.
El objetivo de este estudio es contribuir a la investigación del sharenting en conexión con el marketing de influencers, de madres y padres que utilizan a sus hijos para elaborar contenidos publicitarios. Se busca comprobar la presencia de marcas dirigidas a menores en las publicaciones de sus padres, analizar el uso del derecho a la imagen e intimidad de los menores por sus progenitores y probar si se enmarca en la legalidad jurídico publicitaria española.
Se analiza mediante análisis de contenido la presencia de menores y marcas en una muestra de 89 madres y padres influencers en Instagram (363 post del 20/08 al 20/09 de 2023 y 295 stories).
Los resultados apuntan a una elevadísima presencia de menores en post de madres y padres influencers, convirtiéndose además en vehículos de marcas (con un 96,71% de marcas en posts de madres), aunque menos del 15% de éstas son identificadas como publicidad.
The effectiveness of targeted therapy of various genetically engineered biological drugs in the treatment of bronchial asthma
Authors: Shogenova Madina S.
Published: January 2024

This article presents the experience of successfully switching therapy from omalizumab 150 mg to benralizumab 30 mg/1 ml in a patient with a combined allergic and eosinophilic phenotype in the presence of hypersensitivity to nonsteroidal anti-inflammatory drugs. The effectiveness of biological therapy was evaluated when switching from omalizumab 150 mg subcutaneously at a dose of 600 mg for 36 weeks. Therapy for the drug benralizumab 30 mg/1 ml subcutaneously the first three injections monthly, the rest a month later for 52 weeks with bronchial asthma (BA), a severe uncontrolled course with a combined allergic and eosinophilic phenotype in the presence of hypersensitivity to nonsteroidal anti-inflammatory drugs in a patient Ch., born in 2004. Switching therapy from omalizumab 150 mg to benralizumab 30 mg/1 ml allowed to achieve complete control of asthma symptoms (AST = 23 points), to achieve the absence of asthma exacerbations during 52 weeks, restore respiratory function to normal values, as well as improve the quality of life. The study reflects the good tolerability, high efficacy and safety of biological therapy when switching from one genetically engineered biological drug (GIBP) omalizumab 150 mg to another GIBP benralizumab 30 mg/1 ml in severe uncontrolled asthma with a combined allergic and eosinophilic phenotype in the presence of hypersensitivity to nonsteroidal anti-inflammatory drugs. Therapy with benralizumab 30 mg/1 ml in severe BA has demonstrated a more effective clinically significant improvement in the course of the disease, control of symptoms of the disease. Reduction of exacerbations, normalization of respiratory function indicators, complete control of the disease has been achieved. Consequently, the use of different biological molecules for the therapy of BA with a combined allergic and eosinophilic phenotype contributes to achieving disease control, improving the patient's quality of life and reducing the dose of oral glucocorticosteroids. The targeted biological drug benralizumab 30 mg/1 ml has a targeted effect on the key links in the pathogenesis of severe uncontrolled asthma with a combined allergic and eosinophilic phenotype in the presence of hypersensitivity to nonsteroidal anti-inflammatory drugs and reduces the burden of severe disease.
Long-term consequences of COVID-19 in patients with functional bowel disorders, rehabilitation prospective of microbiocenosis-oriented therapy
Authors: Patsenko Mikhail B.
Published: January 2024

Aim. To analyze long-term consequences of the new coronavirus infection and rehabilitation prospective of microbiocenosis-oriented therapy in patients with functional bowel disorders.
Materials and methods. The study enrolled 100 consecutive patients with various types of functional bowel disorders with recurrence of symptoms after the new coronavirus infection. The severity of abdominal pain was evaluated in points, and bowel movement disorders were assessed using the Bristol stool scale. A questionnaire was used as part of an in-depth clinical examination for COVID-19 survivors to identify the clinical symptoms typical for the post-COVID syndrome. The Hospital Anxiety and Depression Scale was used to identify and assess the severity of depression and anxiety, and the Asthenic State Scale was used to diagnose the asthenia.
Results. All patients in the study subjectively linked the recurrence of bowel disorders with the new coronavirus infection. The most common bowel disorder was irritable bowel syndrome with diarrhea. A distinctive feature of exacerbations of intestinal symptoms in the post-COVID period is their association with depression/anxiety and asthenic states. The addition of Zakofalk® metaprebiotic to the treatment regimen was associated with significant regression of abdominal pain and normalization of bowel movement, an improvement of asthenia, anxiety, and depression.
Conclusion. The addition of Zakofalk® to treatment regimens for exacerbations of functional bowel disorders after the new coronavirus infection significantly improves the effectiveness of therapy.
IMPACT OF TRADE UNIONS’ PRESENCE ON THE ENHANCEMENT OF SAFETY PERFORMANCE OF WORKERS IN THE MARITIME INDUSTRY IN LAGOS STATE
Authors: ADAGBOR Pedro.Uwadum , Ukpere Wilfred , Adekanmbi Foluso
Published: January 2024

Trade unions plays a pivotal role in championing the rights and well-being of workers, including the enhancement of job safety performance. The study investigated the impact of trade unions’ presence in the enhancement of job safety performance of workers in the Maritime industry in Lagos state. Proportionate random sampling technique was employed to select two hundred (200) workers. The data collection instrument consisted of a researcher-designed questionnaire. The data analysis involved pie charts and multiple regression analysis. The findings reveal that trade unions’ presence significantly enhance workers’ adherence to safety regulations and standards to perform their job safely (R=.783, P<0.05); trade unions’ presence significantly enhance safety knowledge and skills of workers to perform their job safely (R=.590, P<0.05); trade unions’ presence significantly improve the provision of proper safety equipment to enhance workers' job safely (R=.671, P<0.05); trade unions’ presence significantly enhance workers with hazard identification and control to perform their job safely (R=.592, P<0.05); trade unions’ presence significantly enhance support to workers who experience injuries or accidents to perform their job safely (R=.671, P<0.05) in the Maritime industry in Lagos state. Considering the findings, it was therefore suggested that trade unions should continue to actively engage with workers and employers to promote adherence to safety regulations and standards; prioritize the provision of safety knowledge and skills to workers through ongoing training programs; actively support employers in ensuring the provision of appropriate safety equipment to workers; work closely with employers to strengthen hazard identification and control processes in the workplace; focus on establishing support systems for workers who experience injuries or accidents.
Isolated Facial Vein Thrombosis in a Case of Lemierre's Syndrome
Authors: V Sane Sudhir , Rokade ML , Limaye Kashmira
Published: January 2024

Lemierres disease is an anaerobic post-anginal sepsis presenting in the form of septic thrombosis of internal jugular vein. A 13-year old boy presented with high fever delirium trismus parotid edema and thrombophlebitis of facial vein. Causative agent was Streptococcus intermedius. The condition responded to metronidazole and linezolid. This case is reported due to its rarity.nbsp
INFLUENCE OF PARTICLE SIZE DISTRIBUTION AND MOISTURE CONTENT VARIABILITY ON THE CHARACTERIZATION OF SOILS IN IPINSA AREA, AKURE, SOUTHWESTERN NIGERIA
Authors: A. Odundun Olumuyiwa , A. Ademeso Odunyemi , S. Ayodele Olusiji
Published: January 2024

Distribution of different sizes of grains has always been useful in estimating other soil properties which will in turn help to understand soil mechanical behavior. Besides, the study area contains soil mass with layering structure which are similar to those exhibited by sedimentary rocks. Hence, the conventional sieve-hydrometer grain size analytical method and another grain size-based classification scheme were employed to characterize soil deposits found within the area of study. Results from this study showed that majority of soil samples are fine-grained. Moreover, silt fractions were found to hold a positive correlation with the effective sizes (D10) while the same could not be said of the sand and clay fractions due to their negative correlations with D10. Data from this study resulted in the zoning of soil into two categories namely; the clayey sandy silts (csSI) and clayey silty sands (csiS). Conditions under which the soils were deposited were deduced from the Silt Fraction (SF) versus Percentage Fines (PF) plot. The plots revealed that majority of the soils within the study area were deposited under low energy and intermediate conditions. A relationship was found to occur between moisture contents in the soil and their resulting zoning. Soils in the silt zone (csSI) have a better overall water content than soils in the sand zone (csiS).
AN EVOLUTION OF THE MAASTRICHTIAN-MIOCENE DISCORBIS PSEUDOSCOPOS-DISCORBIS SCOPOS LINEAGE IN THE SOUTHERN TETHYS
Authors: Salim Anan Haidar
Published: January 2024

A phylogenetic lineage is observed in one of the Rotaliid benthic foraminiferal species throughout Maastrichtian to Miocene in some localities in the Southern Tethys in the Discorbis pseudoscopos Nakkady (1950) → D. duwi Nakkady (1950) → D. convexa Anan (n. sp.) →D. scopos Finlay (1940) lineage. The identified Maastrichtian-Miocene species in this study are recognized in different localities in the Southern Tethys: New Zealand (Pacific Ocean), Egypt (Mediterranean Sea) and Argentina (Atlantic Ocean).
GEOPHYSICAL INVESTIGATION AND GROUNDWATER IN OKPE AND ITS SURROUNDINGS, NIGER DELTA REGION, NIGERIA
Authors: Otitie Star Umayah , Aviedo Edmund Atakpo
Published: January 2024

Geophysical investigation involving groundwater flow modeling was carried out in Orekepe, Delta state to determine the parameters that guarantee groundwater quality. The study entailed the carrying out of twenty-five (25) vertical electrical sounding (VES) using Schlumberger configuration with a maximum current electrode separation of 250 m. VES sounding within the study area was used to calculate transmissivity (T) and hydraulic conductivity (H). Groundwater Vista Version 3 groundwater modeling software was used to calculate the mass balance summary, section raw, and groundwater flow direction using the values of the aquifer parameters that were determined in this investigation. According to resistivity sounding results, the investigation encountered layers that ranged in number from three to four different layers. Further derivation from T and H led to the conclusions that the corresponding values were 0.2694 to 1.9826 m2/day and 0.037 to 0.042 m/day. According to groundwater modeling findings, groundwater moves along the SW to NE axis of the research region with a about 0.002 gradient toward the NE. Based on the direction of groundwater flow, the water-bearing units may be prone to contaminants. It, therefore, recommended that constant monitoring and management of groundwater using several scientific methods should be carried out from time to time.
SIGNIFICANCE OF WELLBORE CLEANUP AND CHEMICAL DISPLACEMENT IN WELL COMPLETION PROCESS OF ELU-01 WELL IN NORTH-EASTERN NIGER DELTA, NIGERIA
Authors: C. Ben Chukwu, , I. Chollom Zi, , A. Paddy Ngeri, , S. Benjamin Udota,
Published: January 2024

This research examines the significance of wellbore cleanup and chemical displacement in well completion process of Elu-01 well in North-Eastern Niger Delta, Nigeria. The aim of wellbore cleanup and chemical displacement is to prepare the well for completion following the drilling phase. Wellbore cleanup is an important component of any well development and completion processes. Failure to successfully clean the wellbore can result to challenges in running the completion tools which may lead to large amounts of non-productive time (NPT) with all the associated risks and monetary costs. Well completions are often comprised of debris sensitive equipment. Failures when running completions can be very costly both in rig time losses and equipment cost. Wellbore cleanup and chemical displacement improves operational efficiency by reducing risk and non-productive time. Wellbore cleanup mechanical tools and chemical displacement flush out debris which obstruct normal well completion operations without damaging the well structure and displaces the drilling fluid (mud oil) to completion brine. Wellbore clean up and debris removal ensures successful completion operations and increases well return fluid as well as the productivity of a well.
Determinants of Leader Visits: A Review and Future Directions in Scholarship
Authors: Balcı Ali
Published: January 2024

A recent surge in studies on high-level leader diplomacy has the potential to evolve into a fruitful research field. While the current literature predominantly focuses on the leader visits of two great powers, the U.S. and China, this emerging field requires both broadening and deepening in its scope. We lack data on leader visits from the vast majority of countries, and many existing hypotheses do not adequately explain the determinants in various cases. The more countries that are covered and the more refined our hypotheses become, the more insightful this field will be in understanding interactions among states and international organizations. This article aims to present the current state of the literature on leader visits and suggests potential areas of interest for future research.
A ETNOMATEMÁTICA NO CONTEXTO DA EDUCAÇÃO DO CAMPO: PERSPECTIVAS DO CURRÍCULO
Authors: Silva Maria Jacqueline da , Formigosa Marcos Marques
Published: January 2024

Neste artigo, apresentamos uma investigação cujo objetivo foi mapear teses e dissertações da literatura brasileira que abordam a Etnomatemática desenvolvida na Educação do Campo, nas perspectivas do currículo. Para tanto, realizamos um levantamento na Biblioteca Digital Brasileira de Teses e Dissertações (BDTD) e no Catálogo de Teses e Dissertações - CAPES; e os analisamos tomando como base o mapeamento horizontal e vertical. Dentre os resultados, temos que, das pesquisas que citaram teóricos e documentos oficiais, a maioria tem mais citações teóricas acerca do currículo do que de documentos oficiais; há pesquisas que têm somente citações teóricas sobre currículo; pesquisas que possuem somente citações de documentos oficiais acerca do currículo, bem como há ainda pesquisa que não tem citações teóricas, tampouco citações de documentos oficiais; há apontamentos dos pesquisadores sobre o currículo, no entanto, sem a indicação de um currículo efetivamente Etnomatemático. Ademais, notamos a importância de ter-se mais pesquisas, no sentido de ampliar os referenciais teóricos que evidenciem a importância das escolas do campo aderirem a práticas de ensino de Matemática na perspectiva da Etnomatemática, bem como construírem currículo nessa perspectiva e que façam  uso de documentos oficiais que tenham orientações curriculares acerca da Etnomatemática desenvolvida na Educação do Campo.
A ALIANÇA DA EDUCAÇÃO STEAM E A PESQUISA-AÇÃO EM DISSERTAÇÕES DEFENDIDAS NO BRASIL
Authors: Coimbra Filho Salvino , Ghedin Evandro , Araújo Cleusa Suzana O. de , Kalhil Josefina D. Barrera
Published: January 2024

Este artigo tem como objetivo apresentar um estado do conhecimento das pesquisas a nível strictu sensu que tematizam sobre a Educação STEAM/STEM e utilizam, de alguma forma, o método da Pesquisa-ação. Para tanto, nos orientamos no seguinte problema de pesquisa: O que revelam os estudos brasileiros, a nível de mestrado e doutorado, que contemplam o tema Educação STEAM/STEM e utilizam o método da Pesquisa-ação? Trata-se de um estudo qualitativo do tipo bibliográfico. Realizamos as buscas no Catálogo de Teses e Dissertações da CAPES e na Biblioteca Digital Brasileira de Teses e Dissertações, obtendo como retorno 26 produções, das quais apenas 04 dissertações foram selecionadas para análise, sendo mapeadas e analisadas na perspectiva da análise de conteúdo a partir de duas categorias: enquadramento da Pesquisa-ação na estrutura metodológica da pesquisa e ressignificação do ensino de ciências utilizando a Educação STEAM/STEM. O estudo revela que as pesquisas strictu sensu tematizando sobre Educação STEAM/STEM ainda são em pequeno número no Brasil; concentram-se no âmbito do Ensino Fundamental e Ensino Médio; contemplam apenas elementos característicos da Pesquisa-ação, mas não assumem o método como sendo a espinha dorsal da pesquisa. As pesquisas retratam a Educação STEAM/STEM como um movimento educacional que suporta as diversas metodologias ativas de ensino além de demonstrar potencial para ressignificar o processo de ensino-aprendizagem, criando condições para transcender as limitações identificáveis no ensino tradicional e proporcionar um ensino integral, baseado no desenvolvimento de habilidades, configurando a intencionalidade de mudança da prática em sala de aula.