bluuebunny/crossref_metadata_2025 huggingface dataset:
Monitoring the change in annual drought conditions in Iraq for the period (1981-2022), using statistical methods and modern technologies
Authors: Al-Masoudi Feraqid Ubid Kazim
Published: September 2024

Climate change is a natural phenomenon that occurs every several thousand years, but with the increase in human activities, climate change has accelerated. Since climate is the average of successive weather conditions in a place over a long period, it may be a month, a season, a year, or several years. Therefore, we find that climatology is concerned with showing the average or median weather conditions prevailing in a region rather than showing daily changes in weather conditions in the region. Therefore, climate change had a significant impact on drought conditions in the location of the study area during the period (1081-2022). The reason for this is that Iraq is characterized by its equatoriality and flat surface in the central and southern regions, which makes it enjoy fast wind movement that raises dust storms that reduce the level of humidity. Stations in southern and central Iraq recorded the highest frequency, represented by the dominance of (south-easterly) winds in the summer season, while stations in the northern region recorded the lowest frequency of this type of wind in the (winter) season. The reason is due to the high temperatures, the variation in humidity, and the frequency of winds in the summer and spring seasons, where air highs prevail and the frequency of air lows decreases, and since climate change causes the retention of rain in the winter with the phenomenon of global warming or the intensity of rain in the spring, summer and fall seasons due to... The phenomenon of convection, which becomes more active due to the heating of the Earth, as well as an increase in the pressure gradient as a result of the deepening of the depression. Seasonal thermal, while the reason for the decrease in wind speed in the fall and winter is due to the lack of thermal activity, the decline of the seasonal low, and the increase in the influence of the Siberian High. Since the drought trend and rising global temperatures have negatively affected drought conditions in Iraq, causing scarcity of rainfall throughout Iraq. Due to the decrease in the frequency of air depressions in the winter, as well as the dominance of air highs, which causes a decline in rain and a lack of humidity or its variation from one region to another, and using statistical methods and the SPSS program, it became clear that Iraq is going through varying periods of drought, which affected the climate conditions over a period of 41 years and during three cycles. Micro-climate cycle and macro-climate cycle.
MATEMÁTICA NA EDUCAÇÃO INFANTIL
Authors: Rezer Aurélia Priscila , Bogo Claudia Seraphim Mano , Neves Elizangela Alves , Oliveira Erileide Araújo De , Santos Roberta Pegorari Bonfim Dos
Published: September 2024

Nos últimos anos, a educação infantil foi se modificando e enfrentando muitos avanços. Mas não devemos sofrer com a perda de uma visão crítica da situação. A primeira experiência foi a primeira etapa da educação básica que tem como objetivo desenvolver a criança até 5 (cinco) anos de idade nos seus aspectos psicológicos, físicos, intelectuais e sociais. A creche e a pré-escola trabalham com que as crianças possam se relacionar com adultos e outras crianças em diferentes situações. A educação infantil é a primeira etapa da criança na escola, começa depois que o aluno adquire seus conhecimentos e habilidades que experimentou em casa e nos lugares para onde viaja. É entender a educação infantil como ambiente social e educativo que proporciona a socialização, colocação, interação e aprendizagem para crianças de 0 a 5 ano.  Entendemos que eles têm características próprias e únicas, o qual deve ser entendido apenas como uma etapa preliminar e preparatória.
A ANÁLISE DE COMPORTAMENTO APLICADA: SUA RELEVÂNCIA NO TRATAMENTO DE CRIANÇAS AUTISTAS
Authors: Sousa Patrícia dos Santos , Rocha Yloma Fernanda de Oliveira
Published: September 2024

O transtorno do espectro autista (TEA) acomete as diferentes áreas do desenvolvimento. A aplicação da Análise do Comportamento Aplicada (ABA) por diferentes profissionais tem demonstrado resultados promissores para alcançar objetivos significativos. Para alcançarmos nosso objeto de estudo, levantamos como questionamento como se dá a análise de comportamento aplicada na pratica e sua relevância no tratamento de crianças autistas? Tendo como objetivo geral analisar como a Análise do Comportamento Aplicada- ABA é aplicada com crianças que estão dentro do transtorno do espectro do autismo. Ressaltando os objetivos específicos de descrever o que é o analise do comportamento aplicada- ABA e o transtorno do espectro do autismo, explicar como a ciência ABA é aplicada com as crianças que estão dentro do transtorno do espectro do autismo e reconhecer a importância da ciência ABA nas terapias com crianças autistas. Para isso usamos autores que nortearam nossa pesquisa, como Benetez et al(2020), Sella e Ribeiro( 2018) Papalia( 2022). Os estudos sobre formação profissional enfatizam a valorização da formação especializada. Foi observado a partir da pesquisa realizada que as revisões de literatura concluem que os processos de intervenção são controversos, caros e dependentes de fatores externos.
HALLAZGOS MÉDICOS SOBRE LA ENFERMEDAD CELÍACA: UNA REVISIÓN BIBLIOGRÁFICA
Authors: Carvalho Ramiro Gedeão De , Costa Cristina dos Santos Doria , Costa Gustavo Doria , Silva Fabio Alexandre da , Paiva Juliana Gamalier de , Paiva Rodrigo Gamalier de , Nascimento Lineise do Carmo Vieira do , Souza Diandra Santos de , Flor Wilma Cecilia Talavera de
Published: September 2024

Celiac disease (CD) is an autoimmune disease characterized by permanent intolerance to gluten due to the abnormal and exacerbated action of the immune system in the presence of this protein and the activation of T lymphocytes in the epithelium of the small intestine, causing atrophy of the microvilli and Nutrient Malabsorption Syndrome (NMS). It has a cosmopolitan occurrence and a prevalence of about 1% of the world population with a clinical picture that varies from mild to severe, representing a public health problem.The aim of this article is to categorize and objectively present the main medical findings in patients with CDin the last three years. In this way, we hope to contribute to academic training, to the updating of
Neurocognitive Stimulation to Improve the Degree of Independence in The Elderly
Authors: Cobo Pedro Fernando Caicedo , Arregui Jennyfer Gabriela Rivadeneira , Vela Flavia Moserrath Chango , Quispe Andrea Elizabeth Villarroel , Morales Gabriela Estefanía Robalino , Chacón Lisbeth Josefina Reales
Published: September 2024

Background: research in the field of neurocognitive therapy to improve visual-motor coordination in the elderly is scarce, so in this study an intervention protocol was implemented through playful exercises that sought to improve coordination between sight and movement execution of this age group, the exercises were worked seeking to integrate the executive functions to them having as; Objective: to improve the visual-motor coordination of elderly residents of the nursing home Sacred Heart of Jesus; Methods:  This research was descriptive based on the quantitative approach with a transversal cut, an initial evaluation was made during the first week through the Barthel index, after this the program was executed for 10 weeks to finally in the last week reapply the Barthel index and thus obtain the results that were obtained with this age group; Results: an improvement was evidenced in the final score compared to the initial where it went from a score of 70. Conclusions: in this work a 12-week neurocognitive training program was established, which showed effectiveness in the improvement of visual-motor coordination and quality of life in general in this age group.
Emergency Nursing Care for Victims of Armed Aggression at the "Sacred Heart of Jesus" Basic Hospital
Authors: Filiación Mariuxi Johanna Zurita Desiderio , Filiación Yulitza Geomara Villamar Torres , Filiación Bertha Alejandrina Vasquez Morán , Chávez Vilma Rocio Quijije
Published: September 2024

In the context of the rise of violence in Ecuadorian society in recent years, care has become increasingly frequent for patients with gunshot wounds in hospital emergencies. In the Basic Hospital "Sacred Heart of Jesus" of the city of Quevedo, this has also been verified in the relevance that the number ofthese cases have acquired. The objective of this article was to know the nursing care practices of victims of assault by weapons in the Basic Hospital "Sacred Heart of Jesus" of the city of Quevedo, given the volume of cases attended of this type of patients, being referred, deceased or not hospitalized. A descriptive research was developed about the procedures and protocols used by nursing staff to respond to these emergencies. The data on admissions and discharges, referred, deceased and non- hospitalized of these cases in the aforementioned care center were reviewed, as well as academic material on the aforementioned topic of the last eight years. It was found that the problem of armed aggression in society has been exacerbated, manifested in the number of emergency cases for this reason in the aforementioned care center and the demands that they meant for the nursing staff, who showed a good mood and professionalism. The discussion of the results showed that the problem of violence due to crime or family violence, constitutes an important public health problem, according to data in Ecuador and other countries. There is an increase in cases of victims of violence and a willingness of professionalism in the nursing staff to deal with these situations, which require a multidisciplinary perspective.
Salmonella Enterica Diarozoniae Strain's Pattern of Increased Antibiotic Resistance
Authors: Askar Esraa Fadhil , Al-karawi Kawthar Kadhim , Salman Khawlah Abdallah , Hussein Hussein Ali
Published: September 2024

Salmonella enterica subsp. diarizonae is a bacterial strain that has been of amassed alarm due to its influence on community health. This bacteria is frequently isolated from cold-blooded reptiles, sheep and monkeys.   Lately, it has been identified from birds migrating transversely the continent of Asia and Europe. This study is the first of its kind  in Iraq to diagnose this serotype of Salmonella from chicken meat and study the level of its resistance to antibiotics. Ten types of antibiotics were used, and this bacteria was extremely unaffected to seven antibiotics out of a total of ten antibiotics and sensitive to only three, with an average diameter of inhibition of Tetracycline 10 mm and Chloramphenicol 7mm. Salmonella were used as a comparison sample, and this bacteria was sensitive to a large number of antibiotics notwithstanding its high resistance to antibiotics, according to a large number of research. The occurrence of antibiotic resistance in Salmonella enterica diarizonae additional confuses the controlling of infections and increases distresses about the efficiency of antibiotic treatment.
Mental Health Disorders of Bulgarian Healthcare Professionals during a Recurring Wave of the COVID-19 Pandemic
Authors: Gidikova Pavlina , Sandeva Gergana , Parusheva Pavlina , Simonov Darko , Baltadzhieva Desislava , Kopraleva Kosara
Published: September 2024

Introduction: During the COVID-19 pandemic, health hazards for medical professionals are associated not only with the high risk of infection, but also with poor working conditions, a stressful psychosocial environment and several socio-demographic factors.
Objectives: The study aims to gain insight into possible mental health disorders among healthcare professionals working in the Bulgarian healthcare system and to determine which professional and socio-demographic categories are most significantly affected.
Methods: This cross-sectional study was conducted in October 2022 in healthcare facilities from seven regions in Southern Bulgaria. A total of 665 workers from hospitals, emergency centers, general and specialized medical practices, and medical laboratories filled out the self-assessment mental health questionnaire DASS-21 (Depression, Anxiety and Stress Scale), as well as a survey about their occupational and socio-demographic characteristics. Suitable statistical methods were used to assess the scientific hypothesis.
Results: 40% of all surveyed healthcare workers had some type of self-reported mental health disorder, with 27% having more than one. 13% had simultaneous signs of depression, anxiety and stress. The rates of depression, anxiety and stress were highest among those working in COVID wards and emergency care centers, among young workers under 26 years of age, and among workers with disabilities and frequently ill workers.
Conclusions: Protecting healthcare workers’ physical and mental health and work ability is a matter of primary importance, particularly under challenging working conditions such as the COVID-19 epidemic.
The Levels and Factors Associated with Access to Primary Care Services among Hypertensive Patients in Muang District, Phetchabun Province, Thailand: A Cross-Sectional Study
Authors: Thammaros Tassana , Taneepanichskul Nutta
Published: September 2024

Objectives: The objectives of this study were to assess the levels of access to primary care services and to identify factors associated with access to primary care services among hypertensive patients in Muang district, Phetchabun province, Thailand.
Methods: The cross-sectional study was conducted in the primary care unit of Phetchabun Hospital from 1 May 2023 to 31 July 2023. Purposive sampling was used to select hypertensive patients to be participants. Data were collected using the questionnaire. Access to primary care services was divided into 4 dimensions (availability, accessibility, accommodation, and acceptability). The mean accessibility score was calculated and interpreted into 3 levels (low-high). Sociodemographic data were analysed as factors associated with access to primary care services using multiple logistic regression. 
Results: A total of 120 participants were interviewed. Male-to-female ratio was 1:2.2. The mean age (±SD) was 61.9 (±6.2) years. Overall, access to primary care was high (3.74±0.62), with accommodation receiving the highest mean accessibility score (4.06±0.66) and accessibility the lowest (3.08±1.12). We found that age ≥ 60 years (P-value 0.039, 95% confidence interval (95% CI) 1.077 – 16.383), living family (P-value 0.018, 95% CI 0.019 – 0.692), living in urban area (P-value <0.001, 95% CI 10.468 - 337.271), employed status (P-value 0.001, 95% CI 2.336 - 30.388) and income >10,000 Baht per month (P-value 0.037, 95% CI 1.102 – 24.642) were associated with access to primary care. 
Conclusions: Overall, the level of primary care access was high.  Age, living status, living area, employed status, and income were significantly associated factors. Expanding primary care services to local levels such as telemedicine might help improve the level of access. The effectiveness of expanding the service should be further study.
The Effect of Parental Support on the Quality of Life of Children with Thalassemia
Authors: Utami Wuri , Nazri Mohd , Mokti Khalid
Published: September 2024

Introduction: Thalassaemia is a blood disorder that is passed down from parents to their children. Patients should receive blood transfusions regularly. Children with thalassaemia will undergo treatment for a long time. These extreme impacts cause various physical, emotional, social, and environmental disorders that can reduce the quality of life of people with persistent thalassaemia major. Objectives: This study aims to determine the effect of family support on the quality of life in children with thalassaemia major. Methods: This research is a type of quantitative correlation with the cross-sectional approach. The sample of all thalassemia patients in April-August 2022 until 2024 Agustus, was 120 pediatric patients selected using the total sampling technique. Bivariate analysis using chi square. Results:  The age characteristics of children with thalassaemia were 83 (69.2%), the majority of females were 65 (54.2%). Family support was mostly positive for 63 (52.5%) and the quality of life of children with thalassaemia was mostly for 64 respondents (65.8%) in the normal category. There is a relationship of family support for the quality of life of children with thalassaemia at the Dr. Soedirman Regional General Hospital, Kebumen. Conclusions: Support family and friends, as well as providing a adequate for parents is very important in improving the quality of life of children Thalassaemia.
Assessing Covi-19’s Effects on Mental Health in Nursing Students During E-Learning in Pandemic
Authors: Gjonej Risida , Gjonej Arben , Poloska Albana , Mataj Elida
Published: September 2024

Introduction: Covid-19 declared by WHO as a pandemic, from the time of experiencing it for the first time until now has caused many deaths all over the world. As a consequence of this pandemic, all public and private institutions tried to adapt life and work. Academic institutions in this period choose to continue with online platforms. This sudden switch from face to face to online learning has caused not only problems during lessons but also in mental and physical health of the students.
Objectives: The study aims to evaluate the level of anxiety among nursing students who study at public nursing faculty in Tirana, Albania.
Methods: A cross-sectional and descriptive study was performed in April- May 2023 at Faculty of Technical Medical Science Tirana, Albania. The study involved nursing students in their third year of Bachelor and first year of Professional Master and Master of Science because only these students have taken online lessons. They were 278 in total.
Results:  The students responded (n = 278) to a questionnaire following GAD7 and HAM-A with some other basic information. Our findings showed that the level of moderate, severe and very severe  anxiety range 30.53%, 3.38% and 1. 53% respectively. A significant relationship was found between gender, age and psychological impact (p=.057; p=.001). The most dominant symptoms were headache (192, 69.10%) and eye irritation (191, 68.70%). 137,49.30% of the respondents think that the lockdown had moderate impact on study.
Conclusions: By applying different methods of assessing the level of anxiety, we found that our nursing students experienced anxiety caused on by the COVID-19 pandemic and isolation just like other nursing students around the world. Designing and consolidating strategies (mental health services or psychological counseling) by faculty members to face similar pandemic situations in the future, would help reduce anxiety among students because they will be professionals tomorrow, thus it is important to take care for their mental health.
Bruxism among young adults (18-30 years) in Albania. A Case Study Analysis
Authors: Qafmolla Alketa , Bardhoshi Esat , Kasapi Viktor , Bardhoshi Merita
Published: September 2024

Introduction: Various pathologies impact the stomatognathic apparatus and are affected by various pathologies, which affect both the dental system and the mastication muscles. A pathology with a high incidence is clenching of the teeth and jaws. The manifestation of this phenomenon is known as "Bruxism", usually linked with the stressful life that humanity is going through. The diagnosis of bruxism is made based on a previously defined protocol that includes anamnesis of disease, extra-intra oral examination, polysomnography. The bruxism can be managed following several procedures: psychological treatment through a psychologist and autosuggestion, drug treatment, and prosthetic treatment through relaxing splints.
The aim of the study is to investigate the presence of Bruxism among young adults aged 18-30 years in Albania. Material and method This study adopts a cross-sectional approach, which encompasses obtaining specific information and advantages at a certain point in time regarding the presence of bruxism and dysfunctional disorders of the TMJ system. about a total of 762 subjects of the age group 18-30 years were interviewed and have completed the questionnaire, during the period October 2022-December 2023.
Result and conclusion Out of 762 examined patients (students), approximately 32.3% were identified with bruxism. The results of the study showed that the majority of cases involved in our study, approximately 74,4% were female. The results of the study showed a statistically significant relationship between age and the presence of muscle pain (prevalence ofp=0.008, and the presence of ATM pain for subjects involved in our study (prevalence of p=0.008), as well as between age and the presence of bruxism at the subjects study (prevalence ofp=0.006).
Assessment of mrkD and T1 fim Genes of K. pneumoniae and Their Association with Biofilm Formation in Community-Acquired Infections
Authors: Ezzulddin Bahasht Y. , Nooraldeen Mohammed Y.
Published: September 2024

Background: Klebsiella pneumoniae is a pathogenic bacteria that can form biofilms on abiotic and biotic surfaces. The constraints of the therapeutic choices against K. pneumoniae arise from its innate capacity to develop biofilm and harboring determinants of multidrug resistance. Objective: The current study aimed to assess the prevalence of some fimbrial genes (type 1 and type 3) of K. pneumoniae strains in community-acquired infections obtained from various clinical sources on their ability to produce biofilm. Methods: A total of 256 samples (106 male and 150 females) were taken from various clinical sources including Urine, wound swabs, sputum, burn swabs, bronchial wash, diabetic foot ulcer, and higher vaginal swabs) from outpatients in Kirkuk City hospitals. The isolates were identified on the Blood agar, MacConkey agar and Eosin Methylene Blue agar based on the cultural, morphological, in addition to biochemical assays, and confirmed using the automated VITEK 2 system. The Microtiter plate (MTP) method was employed to detect Biofilm formation. Subsequently, a polymerase chain reaction was performed to determine the presence of the T1 fim and mrkD genes. Result: Out of 256 only 38 (14.8%) isolates belonged to Klebsiella pneumoniae. Of all isolates, 38(100%) were biofilm producers. The PCR results revealed that all 38 isolates showed positive (100%) for T1 fim and 37 isolates (97.4%) for mrkD.
Benefits of SGLT2 inhibitors on renal and cardiovascular protection, in diabetic patients
Authors: Nelaj Ergita , Kecaj Irida , Feracaku Julinda , Xhixhabesi Kei , Tase Mihal
Published: September 2024

Introduction: Type 2 Diabetes Mellitus is major risk factors for both cardiovascular and renal diseases. Managing cardiovascular risk and the progression of renal disease is therefore essential in treating diabetic patient. Sodium-glucose cotransporter-2 inhibitors have been linked to a substantial decrease in cardiovascular and renal mortality, reduced hospitalizations for heart failure and slower progression of renal damage and albuminuria.
Objectives: Our study aimed to evaluate the impact of SGLT2i on cardiovascular and renal protection in diabetic patients.
Methods: Our study involved elderly patients, with type 2 diabetes, who were divided in two groups, one group received SGLT2i, while the other did not.  Data were collected at the start of treatment, as well as at 3, 6, 9 and 12 months thereafter. During each evaluation, we assessed HbA1C, BMI, GFR and renal parameters, uric acid, NTproBNP, echocardiography, and both PAS and PAD values, in both groups.
Results: Out of 300 elderly diabetic patients included in the study, 200 were started on dapagliflozin 10 mg. At 12 months, HbA1c, weight, systolic blood pressure, NTproBNP, uric acid, albuminuria, were decreases in group with dapagliflozin versus the other group without it, and estimated glomerular filtration rate was higher (75.3 – 87.19mL/min/1.73m2; p<0.005). Follow up in patients with SGLT2i showed a significant decrease in left ventricular end-diastolic dimension (LV-EDD) (62.86 mm to 54.85 mm; P< 0.001) and improvement in LV-EF.
Conclusions: The use of Dapagliflozin demonstrated metabolic benefits in patients with T2DM, including notable decreases in HbA1c, blood pressure, weight, uric acid, and NTproBNP. Additionally, cardiovascular and renal benefits were observed. Therefore, SGLT2i have a significant impact on both cardiovascular and renal protection in diabetic patients.
Exploring Innovative Approaches to Self-Management in Colorectal Cancer for Enhancing Quality of Life and Patient Outcomes - A Scoping Review
Authors: Aryani Ratna , Lalisang Toar JM , Dahlia Debie , Martha Evi , Yulia  , Ibrahim Kusman , Wicaturatmashudi Sukma , Sukarmin  , Hernowo Bingar
Published: September 2024

Introduction: Colorectal cancer is a leading global malignancy, and its diagnosis can significantly impact patients' quality of life. Therefore, exploring innovative approaches to self-management is crucial to empower patients and improve their outcomes. Objectives: This study aims to conduct a scoping review of innovative approaches to self-management in colorectal cancer for enhancing quality of life and patient outcomes. Methods: Literature was selected using the PC (Population, Concept) approach. The literature search was conducted following the PRISMA method. Databases such as PubMed, ProQuest, Cochrane Library, Science Direct, and Google Scholar were used to find relevant articles. Full-text articles published in English in the last ten years were evaluated. Eleven articles met the inclusion criteria.  Results: 11 articles met the inclusion criteria. Innovative approaches to colorectal cancer self-management, such as personalized psycho-educational programs, the use of technology, and structured counseling, show the potential to improve patient's quality of life. Conclusions: Innovative approaches to self-management of colorectal cancer have great potential to improve patient quality of life and treatment outcomes. However, further research is needed to understand the effectiveness of this intervention in the long term. Considering the patient's specific context and needs, these interventions must be integrated into clinical practice.
The Impact of Prenatal Massage Experience Upon The Mother’s Delivery Confidence And Stress/ Anxiety
Authors: Park Joo-Hee , Lee Myung-Sun
Published: September 2024

This study examined the differences in delivery confidence and levels of stress/anxiety among pregnant women based on their experiences with prenatal massage. For this research, the researcher randomly sampled and selected 629 expecting mothers, who were members of an online community for expecting mothers, between August 15 and August 30, 2022, and collected survey data, which was analyzed using the SPSS 25.0 statistical package program. The results of this study are as follows: First, examining the differences in delivery confidence according to prenatal massage experience, it was found that prenatal massage experience has a significant impact on delivery confidence. Mothers with more experience had higher confidence in delivery. Second, prenatal massage experience was found to have a significant effect on the levels of stress and anxiety, with mothers lacking prenatal massage experience showing higher levels of stress and anxiety. The results of this study suggest that professional and systematic education on prenatal massage is necessary to contribute to the development of programs for pregnant women that can increase consumer satisfaction as part of the general prenatal program.
Desafios e Estratégias Multidisciplinares na assistência ao Pré-Natal de Alto Risco: Uma Revisão de Literatura
Authors: De Fátima Simões de Oliveira Maria , Oliveira da Silva Flor Isabela , Laura Ferreira Tavares Anna , Amorim Rodrigues Viviane , Dantas Rangel Cirilo , Borges Silva Larissa , Ilarisse de Carvalho Veneranda , Correia Santa Cruz Lorena , Naraiane Oliveira de Souza Lopes Silvia , Moraes Arcoverde de Macêdo Fabrícia , Parnaíba Maciel Aline , Kethely Batista Dilson Nycole , Gomes da Silva Daniel , Henrique da Silva Neiva Souto Leandro , Israel Fortaleza Santos Allan , Pereira da Silva Anderson Matheus
Published: September 2024

RESUMO:  A gestação de alto risco representa um período crítico que exige atenção e cuidados intensivos, devido às complicações que podem ameaçar tanto a vida da mãe quanto a do feto. Globalmente, estima-se que cerca de 10% a 20% das gestações são consideradas de alto risco. Objetivo: O objetivo deste estudo é revisar sistematicamente a literatura sobre os desafios e estratégias na assistência pré-natal de alto risco, com ênfase na importância da colaboração multidisciplinar. Metodologia:  A revisão foi conduzida seguindo as diretrizes do protocolo PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), garantindo a transparência e a reprodutibilidade do processo. Foram definidos critérios rigorosos de inclusão para garantir a qualidade e relevância dos artigos. A busca bibliográfica foi realizada em múltiplas bases de dados, incluindo BVS, LILACS, PubMed, Scopus e Web of Science. Resultados e discussão: A revisão da literatura revelou desafios críticos na assistência pré-natal de alto risco, sublinhando a necessidade de intervenções oportunas e uma abordagem colaborativa. Um dos principais desafios é a identificação precoce de complicações, como hipertensão, diabetes mellitus gestacional e hemorragias obstétricas, que exigem vigilância constante e intervenções rápidas para prevenir desfechos adversos. Conclusão: Os desafios e estratégias na assistência pré-natal de alto risco, ficou claro que a colaboração entre enfermeiros, médicos, psicólogos e assistentes sociais é vital. Esta sinergia entre diferentes profissionais de saúde é essencial para oferecer um cuidado completo e eficaz às gestantes que enfrentam riscos elevados durante a gravidez.
Palavras-chave: Intercorrências Obstétricas; Emulti; Complicações materno-Fetais.
Autonomy and Democratization of Islamic Education
Authors: Fekrat Izzi , Sepriyanti Nana , Kustati Martin , Nurhasnah Nurhasnah , Eldarifai Eldarifai , Wahyuni Sisri
Published: September 2024

Background. Autonomy is the freedom to maintain and promote the special interests of the region, with its own finances, determine its own laws, and self-government.
Purpose. Educational autonomy according to the National Education System Law No. 20 of 2003 is revealed in the rights and obligations of citizens, parents, communities, and governments.
Method. The research and development method is a research method used to produce certain products, and test the effectiveness of these products.
Results. The results of this paper show that autonomy aims to autonomize a person or an institution or a region, so that educational autonomy has the aim of providing an autonomy in realizing the function of institutional education management.
Conclusion. However, since the implementation of educational autonomy, it turns out that its implementation has not gone as expected, instead the implementation of autonomy has created many problems, namely the high cost of education. Meanwhile, the meaning of educational autonomy actually implies democracy and social justice, meaning that education is carried out in a democratic manner so that the expected goals can be realized and education is intended for the benefit of the community, in accordance with the ideals of the nation in educating the nation.
The Impact of the New Student Orientation Program on the Adaptation Process and Academic Performance
Authors: Mohzana Mohzana
Published: September 2024

Background. The process of adapting new students to an academic environment can be a serious challenge. The new student orientation program is one effort to facilitate their adaptation.  
Purpose. The New Student Orientation Program (POMB) is a critical initiative in helping students cope with significant environmental changes.
Methods. This research aims to evaluate the effectiveness of the new student orientation program in facilitating their adaptation process and its impact on academic performance. Apart from that, to find out the factors that influence the level of successful adaptation of new students will also be analyzed. This research method uses quantitative and qualitative approaches. A survey will be conducted to collect data regarding student perceptions of the orientation program. In addition, in-depth interviews with students and program organizing staff will be conducted to gain a deeper understanding.
Results The research results show that the new student orientation program has a positive impact on their adaptation process. Students who take part in this program tend to have a better level of academic performance compared to those who do not take part in the orientation program. Factors such as social integration, academic knowledge, and psychological support have been shown to play an important role in successful adaptation. Students who take part in the New Student Orientation Program (POMB) experience significant improvements in adapting to the academic environment, create strong social networks, and demonstrate higher motivation.
Conclusion The conclusion of this research is that the new student orientation program has an important role in improving their adaptation process and academic performance. Recommendations for improvements to the orientation program may also be identified, such as increased interactive content and increased post-program support to ensure sustainability of positive effects in the long term.
Strategies to Overcome Barriers and Strengthen Support for Cadre Education Management in Muhammadiyah Collage
Authors: Pribadi Sarli Amri Teguh , Suradika Agus , Bariyah Oneng Nurul
Published: September 2024

Background. Muhammadiyah universities have not been able to carry out good management in solving the problem of regeneration activities. This includes fostering the regeneration of ortoms and education personnel in Muhammadiyah universities in order to produce superior Muhammadiyah cadre candidates for the future.
Purpose. This research aims to analyse in depth the form of cadre activities and the management of the cadre education implementation process at the Muhammadiyah Center of Excellence in Banten Province as well as strategies to deal with inhibiting and supporting factors in cadre management.
Method. In this study, researchers used a qualitative approach (Lexy J. Moleong, 2005: 4) based on phenomenological philosophy by prioritising appreciation(verstehen). Qualitative methods seek to understand and interpret the meaning of an event of human behaviour interaction in a particular situation according to the researcher's perspective (Husnaini, 1996: 81).
Results. The form of cadre activities is carried out in 2 (two) forms including Primary Cadre through Baitul Arqom and Functional Cadre, namely through recitation, Governance / Upgrading Training, Ideopolitor Dialogue (Ideology, Politics and Organisation). Then the implementation of cadre education activities including through IPM (Muhammadiyah Student Association), HW (Hizbul Wathan) and TSPM (Tapak Suci Putera Muhammadiyah).
Conclusion. The research can provide input on how the effectiveness of the cadre education management system can be more effective in producing quality cadres and improving the efficiency of cadre education management by examining the potentials that can be optimised in cadre education management.
The Utilization of the Canva Application Arabic Learning at Baiturrahman
Authors: Shidiq Muhammad Husni , MoHa Luqman , Mudinillah Adam
Published: September 2024

Background. Learning Arabic is often considered difficult and uninteresting by some students. This encourages educators to look for innovative ways to increase students' interest in learning. One way that can be done is to utilize technology in learning, one of which is the Canva application. Canva is an online application that can be used to design various learning media with a variety of attractive templates, as well as a variety of shapes, images, colors, and fonts.
Purpose. This study aims to describe the use of the Canva application as an effort to increase students' interest in learning Arabic. Through the use of Canva, it is hoped that students can be more interested and motivated in learning Arabic, especially in the context of distance learning.
Method. This research uses library research methods. The literature sources used are journals and books relevant to this research topic. The analysis was conducted by reviewing various literature sources that discuss the use of Canva applications in the development of learning media, especially e-modules for Arabic.
Results. The results showed that the Canva app can be used to create attractive e-modules for students. The process of using it includes creating a Canva account, designing modules, selecting and editing backgrounds, adding text, and downloading or sharing design results. By using Canva, students can produce more interesting Arabic teaching materials, so learning becomes more interactive and fun.
Conclusion. The use of the Canva application in making e-modules can increase students' interest in learning Arabic. An attractive and interactive design can make learning materials more lively and not boring, especially in the context of distance learning. Therefore, Canva can be one of the innovative solutions in the development of effective learning media.
Ibn Duraid's Linguistic Thought and Its Influence in Arabic Dictionary
Authors: Sulistya Sulistya , Wahyudi Jarot , Sert Huseyin Emin
Published: September 2024

Background. This study focuses on critically analyzing the method and influence of the dictionary "al-Jamharah," composed by the prolific scholar Ibn Duraid. The development of Arabic vocabularies is essential for understanding the language, and dictionaries play a crucial role as the primary reference for word meanings.
Purpose. The main aim of this research is to explore and critically analyze the methods employed by Ibn Duraid in compiling the "al-Jamharah" dictionary. The study seeks to understand how this dictionary contributed to the development of Arabic lexicography and the influence it had on subsequent linguistic studies.
Method. The research employs a literature review method, which includes collecting bibliographic data, reading, taking notes, and analyzing various sources related to the "al-Jamharah" dictionary. This method allows for a comprehensive examination of the historical context, methodologies, and impact of Ibn Duraid’s work on Arabic lexicography.
Results. The study finds that the "al-Jamharah" dictionary by Ibn Duraid is notable for being the first to use an alphabetical order system, specifically the "aba-jad-un" order. This system was developed to address the difficulties faced by Arabs in understanding the phonetic ordering formed by al-Khalil. The alphabetical method significantly simplified the process of searching for word meanings compared to the traditional phonetic system.
Conclusion. The research concludes that the alphabetical system introduced in "al-Jamharah" provided significant advancements in the field of lexicology, distinguishing it from other linguistic sciences such as qira’at, tajwid, and tafsir.
The Impact of Using Social Media in the Learning Process on Student Social Interaction
Authors: Guilin Xie , Xu Shanshan , Xavier Murphy , Elliot McCarty
Published: September 2024

Background:Social media is a digital platform that allows users to carry out social activities and communicate. Likewise in education, the impact of using social media in the learning process has various impacts. Although social media can increase student motivation and broaden horizons, social media can also make student behavior deviant.
Research purposes:This research was conducted with the aim of knowing the impact of using social media in the learning process, namely to understand how the use of social media affects students' social interactions. Does this influence have a positive or negative impact?
Method:In conducting this research, researchers used quantitative methods in carrying out the research. The data obtained by the researcher was obtained through distributing questionnaires presented by the researcher via a goggle from application. The distribution of this questionnaire is carried out by researchers online, and then the results of the distribution of this questionnaire will be processed using an SPSS application.
Results:From this research conducted, researchers can conclude the research results that the use of social media can help students in the learning process and increase knowledge. However, its use can also cause students' social behavior to become deviant, such as excessive use of social media, laziness in studying, irregular allocation of time for studying, and so on.
Conclusion:Based on the results of this research which discusses the impact of using social media in the learning process on social media interactions, social media has advantages and disadvantages in its use. However, students must be able to use social media wisely, so that deviant behavior does not occur in using social media
EXERCISE-INDUCED SYSTEMIC RESPONSE: THE ROLE OF CIRCULATING EXTRACELLULAR VESICLES
Authors: Caporossi Daniela
Published: September 2024

Regular physical exercise (PE) leads to a systemic adaptation to redox homeostasis perturbation, one of the hallmarks of exercise adaptation. Studies have shown that PE can alter the molecular composition of extracellular vesicles (EVs), impacting their ability to communicate with other cells and modulate physiological processes. EVs circulating in the body and secreted from various cell types, including skeletal muscle cells, contain various regulatory molecules and mediate intercellular communications and tissue cross-talk. Considering that the health-related benefits of a physically active lifestyle are partially driven by various bioactive molecules released into the circulation during exercise, collectively termed “exerkines”, there has been a rapidly growing interest in the role of EVs cargo as “carriers” in the multi-systemic, adaptive response to exercise. Indeed, a potential mechanism by which plasma EVs released during exercise impact ageing and diseases related to redox impairment is increased delivery of redox components, such as redox transcription factors and antioxidants. This presentation will offer a general overview of the biology of exercise-induced EVs and their putative role in health maintenance and disease prevention, with a focus on redox homeostasis control.  
EXPERIMENTAL DATA ON SQUAMOUS CELL CARCINOMA
Authors: Vitsos Andreas , Barda Christina , Gkikas Georgios , Katsiris Dimitrios , Pavlou Panagoula , Kyriazi Maria , Giakoumaki Maria , Parthymos Georgios , Ioanna Papantonaki Anastasia , Ieronymaki Dimitra , Giorak Anna , Chondrogianni Niki , Anastassopoulou Johanne , Vlachodimitropoulos Dimitrios , Sfiniadakis Ioannis , Black Homer , Rallis Michail Christou
Published: September 2024

In recent decades, a global increase in the incidence of skin cancer, particularly squamous cell carcinoma (SCC), has been observed. To explore the pathogenesis and potential therapeutic approaches for this cancer type, in vivo studies employing various mouse models and ultraviolet (UV) light have been conducted. A comparative study on skin carcinogenesis across four hairless mouse models subjected to UV light exposure was initiated. The mouse strains utilized in this research were: SKH-hr1, SKH-hr2, SKH-hr2+ApoE, and immunodeficient Nude. Based on the various measured parameters, in contrast to the SKH-hr1, SKH-hr2+apoE and SKH-hr2 models were identified as the most appropriate.  The bark extract of Pinus maritima (PBE) was examined for SCC preventive action. It was evaluated in two different experimental animal tumor models induced by ultraviolet radiation (UVR) and combination of UVR with 7,12-dimethylbenz[a]anthracene. A significant decrease in the number of animals bearing tumors, increase in viability and delayed appearance of tumors were observed. Through immunochemical analysis, the expression of P-glycoprotein, multi-drug resistance-associated protein (MRP), and glucose (GLUT-1) transporters in SCC, SCC adjacent area, and normal skin tissues were examined. It was revealed that all assessed transporters were expressed across all skin tissues; however, expression levels were notably higher in tumor and tumor-adjacent areas compared to normal tissues. Male and female hairless SKH-2 mice were exposed for 10 months to cigarette smoke (CS) and/or UV light after administration or not of French maritime pine bark extract (PBE) to study the SCC induction and possible protection by PBE. The results showed that UV and CS were harmful and act synergistically inducing SCC, whereas PBE seems to protect skin against SCC. Type 1 and 2 diabetic, and nondiabetic male mice were exposed to UV radiation for eight months. Remarkably, Type 1 diabetic mice did not develop squamous cell carcinoma or pigmented nevi, contrary to normal and Type 2 diabetic skin. Type 1 diabetic mice showed protection against oxidative stress.
RELATIONSHIP BETWEEN PLASMA/ERYTHROCYTES GLUTATHIONE RATIO AND HEALTH STATUS
Authors: Ružanović Ana , Derikonjić Minja , Ristić Radmila , Vasić Marija , Drašković Aleksandra , Milovanović Branislav , Perović-Blagojević Iva , Đurić Strahinja , Kotur-Stevuljević Jelena
Published: September 2024

Considering the crucial antioxidant role of glutathione (GSH) in cells, its assessment is useful for both healthy populations and in different diseases. It is usually measured either in erythrocytes or in plasma, while it is unknown whether the distribution of GSH between these compartments depends on a presence of a disease, thus affecting the results. Therefore, our aim was to investigate the relationship between GSH in plasma and erythrocytes of healthy and diseased subjects. The study included 60 participants, 25 healthy subjects, and 35 patients with different diseases (cancer, heart failure, kidney diseases, chronic fatigue, sarcoidosis, Lyme disease). GSH levels were determined in plasma and erythrocytes using spectrophotometric method with Ellman’s reagent. GSH plasma/erythrocytes ratio between two groups was compared by Mann-Whitney U test and the results are presented as median (interquartile range). The median value of plasma/erythrocytes ratio for healthy subjects was 3.79 (3.32-5.71), and for patients, it was 27.54 (1.53-54.76). This ratio was significantly higher in the group of patients compared to healthy participants (P=0.018). Our results indicate a redistribution of GSH from erythrocytes to plasma in the presence of different diseases. The fact that this preliminary study points out an association of health status with plasma/erythrocytes GSH ratio, regardless of the heterogeneity of a patient group, encourages further research in this direction.