bluuebunny/crossref_metadata_2025 huggingface dataset:
THE RELATIONSHIP BETWEEN RISKS OF OBSTRUCTIVE SLEEP APNEA AND DRY EYE DISEASE
Authors: Aldina Rosy , Yanuar Ferdian , Afif Zamroni , Holipah Holipah , Prayitnaningsih Seskoati
Published: September 2024

Introduction: Dry Eye Disease (DED) may lead to decreased visual function, chronic tissue changes, eyelid, conjunctival, and corneal abnormality. The prevalence of DED in Asia ranges from 21.6%–37.6%. Several studies pointed out the relationship between DED and Obstructive Sleep Apnea (OSA). In patients with OSA, oxidative stress, hypoxia, and ocular surface inflammation increase, leading to a decrease in the functions of meibomian glands, goblet cells, corneal sensitivity, and tear production as a response to the stimulations from the lacrimal glands. The loss of conjunctival goblet cells and meibomian glands are implications of damage to the tear film quality, which results in DED. Method: This is a population-based cross-sectional study. Data were obtained from the database of Biomarker Smarthealth Research in Mendalanwangi, Sidorahayu, and Cepokomulyo Villages, which are located in Malang Regency, having risks of OSA (based on the STOP-BANG questionnaire), above ≥40 years old, and DED Examination with Tear Break-Up Time (TBUT), MGD (Meibominan Gland Dysfunction), Tear Meniscus (TM) involving a total of 518 respondents. The available data were then processed according to the variables and went through DED examinations. This study employed the purposive sampling method. Result: In this study, moderate risk of OSA suggests a significant influence on the occurrence of DED with an odds ratio (OR) 1.66 (p<0.05). In addition, moderate risk of OSA predisposes ADDE (Aqueous Deficiency Dry Eye)-type and Mix-type DED with OR 2.85 and 1.23 (p<0.05). High risk of OSA correlates with the occurrence of ADDE-type DED with OR 2.37 (p<0.05). The age group >60 years old shows a correlation with Mix-type DED with OR 2.09 (p<0.05). Women have a higher predisposition to ADDE-type with OR 2.58 (p<0.05). Conclusion: Moderate risk of OSA influences the occurrence of DED, both ADDE-type and Mix type; whereas high risk of OSA only correlates with ADDE-type. Older age plays a role in the occurrence of Mix-type DED and women have a higher tendency to present with ADDE- type.
CASE SERIES: EFFICACY OF THROMBOLYSIS USING INTRAVENOUS ALTEPLASE IN ACUTE ISCHEMIC STROKE WITH ONSET LESS THAN 6 HOURS (CODE STROKE)
Authors: Maskuri Fajar , Tyas Humaera Elphananing , Tyas Rosyida Evicennianing , Wiastuti Arni , Akhsani Fathiya , Pratama Yanasta Yudo
Published: September 2024

Background: The gold standard therapy for acute ischemic stroke is timely reperfusion of ischemic brain tissue. Intravenous thrombolysis with tPA is the only proven medical therapy for acute ischemic stroke within 4.5 hours of symptom onset using intravenous alteplase at a dose of 0.9 mg per kilogram of body weight. Hemorrhagic transformation is one of the complications of thrombolytic therapy and East Asian population having a higher prevalence of cerebral hemorrhage. This study will examine several cases of ischemic stroke that were treated with thrombolysis using a standard dose (0.9 mg/kg) of intravenous alteplase in acute ischemic stroke with an onset of less than 6 hours in the Special Region of Yogyakarta, especially at the UGM Academic Hospital. Objective: To determine the efficacy of standard dose thrombolysis using intravenous alteplase (rTPA-recombinant tissue plasminogen activator) in acute ischemic stroke with an onset of less than 6 hours through activation of the Code Stroke. Methods: Descriptive research design using a case series, the hyperacute stroke patients with an onset of less than 6 hours who received intravenous alteplase which were then assessed by the National Institutes of Health Stroke Scale (NIHSS) score at initial admission, 24 hours post-alteplase and 30 days post -alteplase. The study took place and was conducted from May to October 2022 by administering intravenous alteplase at a dose of 0.9 mg/kg body weight in acute ischemic stroke patients at UGM RSA who are eligible for thrombolysis therapy with a maximum administration time of 6 hours after stroke onset with the maximum dose of alteplase is 50 mg. Results: The study sample was 8 patients with acute ischemic stroke who were treated between May to October 2022. There were 2 patients who died before completing the 3-month follow-up. One of the patients died within the second week of treatment from sepsis which may have occurred from a pre-existing pneumonia. Another patient died from ileus that occurred 1 month after tissue plasminogen activator (tPA). However, the patient with this ileus showed clinical improvement at the 24-hour post-tPA follow-up, i.e. the initial NIHSS score of 12 improved to an NIHSS score of 6. Conclusion: The modified Alteplase dose, which is 0.9 mg/kg body weight with a maximum dose of 50 mg, at the onset of stroke less than 6 hours can be an option to maximize thrombolytic therapy while still considering the efficiency of treatment costs.
Impact of calcination technology on properties of calcined clays
Authors: Martirena Hernández José Fernando , Antoni Mathieu , Oquendo-Machado Yanisleidy , Borrajo-Perez Ruben , Alujas-Diaz Adrian , Almenares-Reyes Roger
Published: September 2024

Calcined kaolinitic clays are known to be very reactive pozzolans, and combined with limestone can enable significant clinker substitution in cementitious systems. Thermal activation of kaolinitic clays takes place when the hydroxyl groups are removed, leading to formation of an amorphous reactive structure. There are several technologies for clay activation, but the most used at industrial scale are flash and stationary calcination. The objective of this paper is to investigate the impact of the calcination regime on the properties of the calcined product. It presents the results of an experimental program carried out with a kaolinitic clay calcined at a flash calciner and at a laboratory furnace. Calcination brings about a drop in specific surface, and an increase of average diameter due to agglomeration, an effect more pronounced in stationary calcination. No major differences were found at the heat of hydration, CH consumption and phase assemblage for the fully dehydroxylated material. The flash calcined material had slightly better results mainly due to a finer PSD compared with the one stationary calcined. No major difference was found in water demand and compressive strength for both regimes. As expected, the main impact of the calcination regime is the agglomeration.
Impact of irregular masonry infill walls on the seismic response of reinforced concrete frame buildings using linear dynamic analysis
Authors:   Faculty of Engineering, Lincoln University College, Petaling Jaya, Malaysia, Shrestha Ram Krishna , Alagirisamy Mukil ,   Faculty of Engineering, Lincoln University College, Petaling Jaya, Malaysia, Dangol Purushottam ,   Faculty of Engineering, Kantipur International College, Purbanchal University, Lalitpur, Nepal, Pradhananga Binod ,   Faculty of Engineering, Khwopa Engineering College (KhEC), Purbanchal University, Bhaktapur, Nepal, Giri Om Prakash ,   Faculty of Science and Technology, Pokhara University, Pokhara, Nepal
Published: September 2024

This paper aimed to investigate the seismic response of reinforced concrete (RC) frame buildings using linear dynamic analysis. The study focused on the effects of irregular distributions of masonry infill walls both in elevation (soft story at different levels) and in horizontal (plan) distribution on seismic behavior. Seventeen models were analyzed, including infill frame models with soft stories, models with infill panels only in certain bays, and bare frame models. All models were analyzed using the linear response spectrum (RS) dynamic analysis method. Structural design typically focuses on peak response values, and response spectrum analysis examines the structure's behavior and performance through these peak values. The analysis results indicate that masonry infill walls significantly affect the building's fundamental time period, base shear, story shear, and inter-story drift.
Implementing adaptive learning technologies: Practical strategies for enhancing cognition in mathematics education
Authors:   Special Education Department, King Khalid University, Abha, Saudi Arabia, Khasawneh Mohamad Ahmad Saleem
Published: September 2024

Recent studies have shown that adaptive learning technology can significantly change mathematics teaching. This research used a combination of methods to explore how adaptive learning technologies (ALTs) can improve cognitive abilities in math instruction. The study involved 300 secondary school students. Quantitative data was collected through pre-tests and post-tests to evaluate problem-solving, critical thinking, and logical reasoning skills, as well as a survey on students' opinions about ALTs. Qualitative data was gathered by analyzing participant responses in depth. The quantitative data was analyzed using descriptive statistics, paired samples t-tests, ANCOVA, correlation analyses, and regression analyses. The qualitative data was examined using thematic analysis. The results showed significant improvements in cognitive abilities with the use of ALTs, supported by both quantitative and qualitative data. Additionally, using ALTs was positively linked to the development of cognitive skills. These findings enhance our understanding of the importance of ALTs in mathematics education and provide useful insights for teachers, curriculum developers, and policymakers.
Pojam i analiza implementacije koncepta aktivnog starenja u međunarodnopravnom i hrvatskom pravnom sustavu
Authors: Balog Nevia , Rešetar Branka
Published: September 2024

Uslijed višegodišnjeg i aktualnog trenda demografskog starenja stanovništva pitanje ljudskih prava i socijalne uključenosti starijih osoba sve više dobiva na značaju. Starije osobe povijesno su smatrane ranjivom skupinom u društvu zbog ovisnosti o drugima, što zbog bolesti, slabosti ili trajnog invaliditeta. Upravo stoga je ova kategorija ranjivih osoba često izložena višestrukim diskriminacijama. U posljednja dva desetljeća sve je aktualniji „koncept aktivnog starenja“ kao suvremeni odgovor na potrebe starijih osoba, uključujući starije osobe s invaliditetom. Koncept aktivnog starenja predstavlja smjer politika, strategija i akcijskih mjera koje su usmjerene na poboljšanje kvalitete života starijih osoba s ciljem produljenja životnog vijeka i što dulji ostanak u obitelji i zajednici. Ono uključuje zaštitu prava na zdravstvenu zaštitu, socijalnu uključenost, doprinos životu zajednice, kao i ravnopravno sudjelovanje u kulturnom i društvenom životu zajednice. U radu se analiziraju implementacija i zastupljenosti koncepta aktivnog starenja u politikama i strategijama te pozitivnopravnim hrvatskim i međunarodnim propisima. Ujedno se postavlja pitanje usklađenosti hrvatskih politika i propisa s međunarodnim standardima u području prava starijih osoba i koncepta aktivnog starenja.
Popular Skin-of-Color Dermatology Social Media Hashtags on TikTok From 2021 to 2022: Content Analysis
Authors: Kang Jeemin , Szeto Mindy D , Suh Lois , Olayinka Jadesola T , Dellavalle Robert P
Published: September 2024

TikTok is a social media platform that can educate users about dermatology, but this longitudinal analysis of skin of color–related TikTok hashtags from 2021 to 2022 suggests that nondermatologist influencers continue to dominate content creation, highlighting the need for more participation from board-certified dermatologists to actively counter misinformation and address potential disparities in skin-of-color health care.
Supporting Weight Loss Among Parents of Children With a Disability: Lessons Learned From a Single-Arm Pilot Study
Authors: Wisniewski Payson , Depuy Julia , Kim Cassandra , Garrison Olivia , Jerome Gerald J
Published: September 2024

This study assessed weight change in the parents of children with disabilities following a 12-week, remotely delivered weight loss program focused on lifestyle modifications and found a significant median weight reduction of 3 kg from baseline to week 12.
Providers’ Perspective on the Feasibility of a Digital Self-Management of Blood Pressure in Refugees: A Mixed Methods Study (Preprint)
Authors: Gonzalez Carol , Real Marcos , Ahmadi Nargis , Aljenabi Raghad , Bridi Lana , Makarem Nour , Godino Job , Al-Rousan Tala
Published: September 2024

BACKGROUND

Mass displacement is a grand public health challenge. Refugees experience a disparate hypertension (HTN) burden and disparities in self-management. Successful HTN self-management is key for improving outcomes, but research on its feasibility in refugee healthcare settings is limited.

OBJECTIVE

Our aim was to assess the perspectives of refugee health providers on telemonitoring home BP management using connected BP monitors.

METHODS

Primary care physicians (PCPs) and medical assistants (MAs) that care for refugees in San Diego were interviewed using human-centered semi-structured methods (n=18). Interviews were analyzed using an inductive approach. Usability testing for the BP software (Med Pro Care) was conducted with participants (n=15) to test the feasibility of real-time tracking of BP home readings. Providers rated their satisfaction on a System Usability Scale and the NASA Task Load Index which measures mental workload.

RESULTS

For refugee patients self-managing HTN, providers identified the following as facilitators: 1) family support, 2) language resources, and 3) trust. The following barriers were identified: 1) life stressors, 2) language barriers, 3) cultural differences, 4) socioeconomic status, 5) lack of awareness, and 6) unavailability of equipment. PCPs completed 90% and MAs completed 83% of the tasks successfully. The majority of providers found the software system for self-management of HTN to be easy to use with an average score for usability of 3.59 out of 5 (SD ± 0.76).

CONCLUSIONS

Identified barriers and facilitators of self-management of HTN are crucial to designing effective interventions in real-world refugee healthcare settings. Telemonitoring interventions using software that transfers BP readings to providers in real time may be feasible from the perspective of healthcare providers and can address hypertension disparities in marginalized populations.
Study protocol: Investigating the role of Coenzyme A restriction in the pathophysiology of Pre-eclampsia (Preprint)
Authors: Al-Jayyousi Reem , Jan Reem Kais , Giddey Alexander D , stanley Adrian G , Parambath Anagha , Mirza Fadi G , Radhakrishnan Rajan , Atiomo William , Hodgman Charlie
Published: September 2024

BACKGROUND

Pre-eclampsia is one of the three leading causes of maternal mortality worldwide. Un-fortunately, the exact pathogenesis is still unclear. Published metabolomic and gene expression analyses point to Coenzyme A restriction in the placenta as a factor under-pinning the observed complications of pre-eclampsia, but this hypothesis has never been tested.

OBJECTIVE

Investigate the role of CoA restriction in pre-eclampsia

METHODS

This manuscript provides a rationale and a protocol for a clinical study and laboratory experiments to test this hypothesis. It involves screening pre-eclamptic patients for elevated levels of key toxic metabolites induced by the restriction. The laboratory study will involve treating cultured trophoblast cells in a variety of ways to determine if Co-enzyme A restriction can be induced. It involves both metabolite profiling of the culture medium for the toxic metabolites and expression profiling of key genes.

RESULTS

Patients are currently being recruited into the clinical study, and preliminary results will be published in 2026.

CONCLUSIONS

The findings of this study will indicate if Coenzyme A restriction is associated with pre-eclampsia. If so, this provides a significant novel avenue for research into the treatment and prevention of the disease.

CLINICALTRIAL

Not applicable
Cryptic Diversity of Barred Mudskippers, Periophthalmus argentilineatus (Valenciennes, 1837), from the Southern Coast of Java and East Lombok, Indonesia inferred by COI Mitochondrial Gene
Authors: Arisuryanti Tuty , Aji Katon Waskito , Herawati Happy , Sari Indah Paramita , Rha’ifa Febrina Amaliya , Febriyanti Diana , Priyono Dwi Sendi
Published: September 2024

The Barred Mudskipper (P. argentilineatus) is an amphibious fish species that displays fully terrestrial behaviour during low tides. Previous studies have indicated the existence of cryptic species of the barred mudskipper, leading to difficulties in taxonomic identification due to similarities in morphological characteristics. Therefore, this study aimed to generate DNA barcodes for Indonesian barred mudskipper populations. We collected ten specimens from Clungup Beach and Kondang Bandung Beach, representing our samples. Additionally, we incorporated 25 previously collected COI sequences from Indonesia into our analysis. The mitochondrial COI gene was amplified using PCR and analysed using various bioinformatics programs. This study provides evidence for the presence of three genetically distinct clades (A, B, and C) within the P. argentilineatus population in Indonesia, with a deep genetic divergence of 2.41% to 6.12%. Clade A showed a high genetic divergence of 5.51-6.12%, suggesting the presence of a cryptic species consistent with previous studies. The high level of haplotype diversity and low nucleotide diversity observed in each clade suggest a population bottleneck followed by a rapid expansion. The lack of geographical separation in the haplotype network analysis indicates that gene flow between populations may have been facilitated by glaciation events in the past. These findings contribute to a better understanding of the biodiversity of the barred mudskipper species in Indonesia and will aid in the accurate identification of cryptic species. This study highlights the importance of using molecular techniques to complement morphological identification in understanding the evolution and diversity of mudskipper fish species.
Herpetofauna and Their Potential Threats in Karimata Island, Indonesia
Authors: Pratama Ferdian Wira , Fauzan Opi , Luthfi Muhammad
Published: September 2024

Karimata Island is an island about 100 km west of Borneo, causes geographical isolation and generally always shows an impact on the diversity of animal communities that are less, one of the communities affected is herpetofauna. Herpetofauna is very important in an ecosystem so it is necessary to conduct a survey. The survey was conducted from April 1 to April 7, 2023 in Betok Jaya Village, Karimata Island which was divided in 3 observation areas based on habitat type using the Visual Encounter Survey method. Herpetofauna found consisted in 22 species divided into 5 species of amphibians and 17 species of reptiles with a total of 43 individuals. Herpetofauna located adjacent to human areas is vulnerable to various disturbances such as maritime transportation activities, household waste pollution and land clearing, which can be a threat to the herpetofauna community of Karimata Island.
The Diversity of Ants (Hymenoptera: Formicidae) on Industrial Forest in Sungai Merah Village, Sarolangun, Jambi with Its Identification Key
Authors: Fitriyani Nur Laras , Soesilohadi RC. Hidayat , Purwanto Hari
Published: September 2024

Ants have a very important role in an ecosystem. The insects act as decomposers, pollinators, soil aerators, pest controllers, and predators. Their role is very varied so that they can be easily found in various ecosystems, one of which is the rubber and oil palm ecosystem. The ant’s diversity in this forest eventually will affect the productivity of the land. The aim of this study is to determine the diversity and role of ants in the rubber and oil palm plantations in Sungai Merah Village. Both of the plantations dominate the industrial forest in Jambi. The method used in this study was purposive random sampling. Observation plots were installed in the ecosystem of rubber and oil palm plantations; each ecosystem had 4 plots consisting of 9 units of pitfall traps, and 9 units of bait traps. The results of this study show that 15 species of ants are found in the ecosystem of rubber and oil palm plantations. Furthermore, the collected ants consisted of 39.972 individual ants belonging to 12 genera and 5 subfamilies. Ants establish in the ecosystem of rubber and oil palm plantations in Sungai Merah Village have an important role either as predators (Crematogaster spp., Odontomachus rixosus, Odontoponera tranversa, Pheidole huberi, Tetraponera rufonigra, Tapinoma melanocephalum, Camponotus spp. and Colobopsis moeschi), or foragers such as ants from the genera Anoplolepis, Camponotus, Monomorium and Polyrhachis. As predators, Oecophylla smaragdina, Camponotus spp. and Crematogaster spp. also play a role as biological control agents in the ecosystem.
Detection of Entomological Origin of Honey Sold in Indonesia Based on 16S rRNA Gene Analysis
Authors: Indahsari Anita Nur , Purwanto Hari
Published: September 2024

Honey is known for its various benefits for health, cosmetic ingredients, and other industrial materials. Especially, during the Covid-19 pandemic, many people consume honey to maintain body endurance. In Indonesia, the honey produced is dominated by Apis mellifera honey. With a cheaper price and a larger quantity, A. mellifera honey is often offered as forest honey or stingless bee honey to get more profit. Therefore, this study aims to determine the entomological origin of honey claimed as forest honey and stingless bee honey sold in the Indonesian market using the detection of 16S rRNA gene amplicon. This study tested 30 samples of forest honey and 30 samples of stingless bee honey. DNA that has been isolated from honey samples was amplified by PCR using 16S rRNA primers. The results from the sequence analysis showed that nine of honey samples were identified as honey fraud. Two samples were confirmed as falsification of the origin of honey-producing bees and four honey samples were confirmed as honey mislabelling. From this study it can be concluded that, it is possible to determine the entomological origin of honey molecularly by sequencing the 16S rRNA gene. Therefore, this method can be used to identify honey fraud that may occur on the market.
Fern Species-Area Relationship in Urban Anthropogenic Islands in Slawi, Tegal, Central Java
Authors: Sedayu Agung , Putri Novita , Aminudin Aminudin , Mawardi Muchtar , Noer M. Isnin , Maulana Lana
Published: September 2024

In anthropogenic islands as urban parks, the fern species richness and composition may be determined ecologically by the quality of habitat, including area greenness, or biogeographically by area size. As the development of the theory of island biogeography also includes man-made parks, it is feasible to test whether area-species relationship applies in these urban parks, and is more pronouncedly evident compared to another ecological factor, such as NDVI. Total species number and composition of 8 urban parks in a kecamatan in Tegal Regency were collected and arranged in clustering methods to understand the similarity between parks. The similarity analysis result is important for the management of the parks in Slawi. The species richness data is subsequently tested using Pearson correlation and regression against NDVI and area sizes. The relation between NDVI and species richness is non-significant (p=0.058), while area size and species richness is significant (p=0.003). This signifies that the urban fern species richness is determined by area as biogeographical factor, compared to NDVI as ecological factor. This result is important for the purpose of designing and managing urban parks as evidently size is important in the effort of attracting native biodiversity into urban parks and in turn enhancing the well-being of urban population.
Mining GATA Transcription Factor Encoding Genes in The Cocoa Tree (Theobroma cacao L.) Suggests Their Potential Roles in Embryo Development and Biotic Stress Response
Authors: Chu Ngoc Thi Bich , Le Thi Man , Chu Ha Duc , Tran Huyen Thi Thanh , Tran Lan Thi Mai , La Hong Viet , Vu Quyen Thi Xuan , Phung Huynh Huy , Cao Phi Bang
Published: September 2024

GATA transcription factors (TFs) are widely recognized as significant regulators, characterized by a DNA-binding domain that consists of a type IV zinc finger motif. This TF family has been widely investigated in numerous higher plant species. The purpose of the present work was to comprehensively analyze the GATA TF in cocoa plant (Theobroma cacao L.) by using various bioinformatics tools. As a result, a total of 24 members of the GATA TFs have been identified and annotated in the assembly of the cocoa plant. According to phylogenetic analysis, these TcGATA proteins were classified into four distinct groups, including groups I (10 members), II (seven members), III (five members), and IV (two members). Next, our investigation indicated that the TcGATA proteins in different groups exhibited a high variation in their physic-chemical features due to their different protein lengths, gene structures, and conserved motif distributions, whereas the TcGATA proteins in the same clade might share the common conserved motifs. Additionally, the gene duplication of the TcGATA genes in the cocoa plant was also investigated. Of our interest, the relative expression levels of the TcGATA genes were investigated according to available transcriptome databases. The results exhibited differential expression patterns of all TcGATA genes in various developmental stages of zygotic and somatic embryogenesis, indicating that these TcGATA genes divergently function during various developmental stages of the zygotic and somatic embryos. Moreover, TcGATA genes were differently expressed under Phytophthora megakarya treatment across different points of treatment and cocoa varieties. To sum up, our findings could provide a basis for a further deep understanding of the GATAs in the cocoa plant.
Diversity of Orchid species in the Tilu Mountains Region of Indonesia and the Potential for Phytochemistry
Authors: Prapitasari Bela , Rezaldi Taufiq , Kenza Masfufah Lutvita , Aliwafa Ahmad , Gunawan Dwi Ariya , Nuraini Latifa
Published: September 2024

Orchids are one of the largest and globally distributed plant families. Indonesia has the most types of orchids, estimated around 20% from the total species across the world. Mainly orchids used as an ornamental plant. This research aimed to elucidate another potential of orchids as possibly for herbal medicine plant. The potential of orchids as herbal medicine has been known for a long time, but there is lack of well-documented research. The research method used in this research is exploration on predetermined research sites that were conducted in Mount Tilu, West Java on 2022. Observation data of orchids were collected on the sites and the analysis was carried out in a qualitative descriptive approach by describing the data from the research results and comparisons were made through a literature review. Based on the research results, we found about 31 species from 28 genera consisting of 24 epiphytic orchids and 7 terrestrial orchids in the Mount Tilu Kuningan area, West Java. There are 4 endemic species categorised in Java; Chilochista javanica, Crepidium koordesii, Crepidium junghuhnii, and Taeniophyllum biocellatum.
SiDREB2-based SNAP Marker-Assisted and Multi-Trait Selection in The Early Generation of Foxtail Millet (Setaria italica L. Beauv.)
Authors: Butarbutar Lidya Kristina Sari , Syawaluddin Dwi Dana , Suwarno Willy Bayuardi , Ardie Sintho Wahyuning
Published: September 2024

Setaria italica L. or foxtail millet is known for its nutritious grains and adaptability to unfavorable environmental conditions. High productivity, early heading, medium stature, and tolerance to drought- or salinity stress are among the breeding objectives for foxtail millet. The objective of this study was to select F3 families of foxtail millet from the cross of Botok-10xICERI-6 by weighted selection index and assisted by SiDREB2-based SNAP marker. Genotyping of 178 F3 families using the SiDREB2-based SNAP marker resulted in 29 A/A genotypes, 121 A/G genotypes, and 28 G/G genotypes. Further evaluation was conducted on 48 F3 families consisting of 27 A/A genotypes and 21 A/G genotypes in an augmented randomized complete block design together with their parental genotypes (Botok-10xICERI-6) and three check genotypes (Mauliru-2, NTB-1, and Toraja). Plant height and heading time had high broad-sense heritability, whereas grain weight per plant had a moderate broad-sense heritability. Ten potential F3 families were selected based on a weighted selection index with 20% intensity, comprised of seven A/G genotypes and three A/A genotypes with a weighted selection index ranging from 0.84 to 3.76. The F3 family with pedigree numbers B10I6-15-136, B10I6-15-161, and B10I6-15-70 with A/A genotypes are considered putative transgressive segregants and could be continued to the next generation for further breeding process.
Characterization of Flower’s Color based on CHS Gene Structure in Phalaenopsis ‘OX Queen’ and Dendrobium ‘Cheddi Jagan’ Orchids
Authors: Hanifa Yumna Rahmadias , Gildantia Elke , Kasi Pauline Destinugrainy , Purwantoro Aziz , Semiarti Endang
Published: September 2024

Orchids (Orchidaceae) are ornamental plants known for their high aesthetic value attributed to the shapes, colours, and fragrances of their flowers. Two types of hybrid orchids with attractive flowers, namely the Phalaenopsis 'OX Queen' orchid and the Dendrobium 'Cheddi Jagan' boast attractive flowers were used in this research, because of the beauty of its flower colour. The objective of this research is to characterise the morphology of flower colour and CHS (Chalcone Synthase) gene content that induces flower colour. The method used in this research analyzing the flower’s colour by using the RHS (Royal Horticultural Society) colour chart and molecular analysis by DNA genomic isolation and PCR amplification of gDNA for CHS gene specific primers. The results showed that purple colour is observed through the RHS, with P. 'OX Queen' coded as Deep Purple Pink (N73A) and D. 'Cheddi Jagan' coded as Strong Reddish Purple (N72C). The CHS gene can be amplified in P. ’OX Queen’ 1,287 bp and D. ’Cheddi jagan’ 3,731 bp. In both orchids, the results of amplification showed CHS motifs with conserved domains PLN03172 and PLN03170. The research results show that there is a significant difference in the morphology of the flowers of orchids. Purple colour is observed through the RHS, with P. 'OX Queen' coded as N73A and D. 'Cheddi Jagan' coded as N73C. The results showed that gDNA can be isolated by using CTAB method according to Murray and Thomson, and the CHS gene can be amplified by using CHS primers, resulting 1200 bp of P. 'OX Queen' and 2500 bp for D. 'Cheddi Jagan'. Through this study, preliminary data is expected to be obtained for future research, which is the formation of variegated flowers through editing the CRISPR/Cas9 genome in the CHS gene. This research is intended to support further studies on the formation of variegated flower patterns in P. 'OX Queen' and D. 'Cheddi Jagan’, focusing on the CHS gene using CRISPR/Cas9 technique.
Review of the new facts or new news contained in article 321 of the Chilean Civil Procedure Code
Authors: Alarcón Machuca Carlos
Published: September 2024

This paper aims to address the procedural figure of new facts or newly discovered events, recognized in some continental Procedure Codes. In this context, we will examine certain historical sources that influenced its modern legislative reception, intending to understand the institution’s meaning, which is usually studied from an evidentiary perspective, with Chilean Civil Procedural Law serving as an example. In contrast to the above, our manuscript will assert that the new facts or newly discovered events , contained in article 321 of the Chilean Código de Procedimiento Civil, operate as a legislative mechanism aimed at incorporating new factual background, expanding the subject matter of the trial, and breaking the fiction of immutability of the process derived from the general principle of the doctrine of lis pendens, which justifies the application of the institution to the Chilean labour process.
Las soluciones del derecho internacional privado español frente a la violencia de género
Authors: Moreno Sánchez-Moraleda Ana
Published: September 2024

El objetivo de este trabajo es hallar los instrumentos de derecho internacional privado español que protegen a la mujer víctima de violencia de género. Para ello, se investiga la normativa aplicable que permite conocer a determinados órganos jurisdiccionales que van a aplicar la ley más favorable que no vulnere el orden público internacional. No obstante, siguen existiendo países que autorizan los matrimonios forzosos y el repudio unilateral del marido. En consecuencia, se estudian los mecanismos jurídicos para evitar la violencia de género en estos casos.
Constitución y poder
Authors: Valadés Ríos Diego
Published: September 2024

El poder político lleva milenios siendo estudiado; y seguirá estudiándose porque es un fenómeno social cuya fluidez hace que de continuo ofrezca elementos para su análisis. Como expresión de fuerza y como capacidad para imponer conductas, el poder es un hecho social presente en todos los grupos humanos. Su regulación germinal corresponde a las primeras formas de organización; cuando los detentadores del poder adoptaron regularidades elementales, comenzó a darse lo que se identifica como Estado arcaico. Este ensayo atañe a las diferentes formas de entender el poder que tienen relevancia para el ordenamiento constitucional.
Affective Milieu in Children’s Museum Experiences: An Ethnographic Study With Young Visitors at the Danish Workers Museum
Authors:   , Steinbeck Stefanie Hansen
Published: September 2024

Inspired by the affective turn in humanities and social sciences, this thesis explores affective milieu in young visitors' interactions at the Workers Museum in Copenhagen, Denmark. Affective milieu are defined as complex tangles of everyday affect relations that encompass social and material interactions, shaping and being shaped by relational conditions and power dynamics within museum spaces. Employing an anthropological approach and utilizing ethnographic methods, this research emphasizes the affective dimensions of children’s museum experiences. It investigates these dimensions through three distinct articles, each examining different roles children assume in museum spaces—visitors, students, and collaborators. The findings across the three articles indicate a significant shaping of children's experiences by the affective dynamics present and constructed within these spaces. This thesis demonstrates that children navigating these museum environments are not passive recipients but active agents, whose experiences are significantly shaped by the affective dynamics of their surroundings. From the physical design of the museum to interactions with staff and other visitors, every element contributes to the construction of affective milieu that influence children's emotional experiences and engagement. The study portrays that children’s museum experiences are intricately constructed through, with, by, and off affective milieu. Aligning with contemporary calls for affective curatorship, the thesis argues for a reimagined approach to museum curation that prioritizes affective encounters. Such encounters are pivotal in enhancing the educational and emotional richness of museum visits, offering a more inclusive and engaging experience. This paradigm shift not only challenges traditional museum practices but also acknowledges the dynamic, co-constructed, and ongoing nature of museum experiences. By embracing affective milieu, museums can foster environments that invite interaction, reflection, and immersiveness while recognizing that not everything can be constructed or predicted by design.
Nexus between ESG Practice and Firm Performance: Are there any Stylised Facts?
Authors: Yip Tien-Ming , Lau Wee-Yeap
Published: September 2024

This study examines the relationship between firm performance and ESG (environmental, social and governance) practice for Malaysian public-listed companies. It evaluates whether the relationship varies with firms’ market capitalisation, total liabilities, and free cash flow. Using firm-level data from 72 companies covered in the FTSE4Good Bursa Malaysia (F4GBM) index from 2014 to 2022, our results show the following. First, ESG practice is positively and significantly associated with firm performance. However, the positive impact is conditional on the firm-specific variables. In particular, the positive impact of ESG is significant for firms with high market capitalisation. Second, the positive impact of ESG diminishes as firms accumulate higher liabilities. Third, the positive impact of ESG prevails if firms attain a high level of free cash flow. Our results suggest that firms must increase their market capitalisation, reduce total liabilities, and improve their free cash flow to benefit from ESG practices.
Shakespearean Tradition in the Contemporary British Novel: Ian MсEwan
Authors:   Institute of Social Sciences Information (INION) of the Russian Academy of Sciences, Krasavchenko Tatiana N.
Published: September 2024

Ian McEwan (born 1948), one of the most outstanding contemporary British writers, is brought to the literary forefront thanks to the current social, ethical issues and aesthetic virtues of his works and belonging to the New Time British Gothic tradition whose foundations were laid by Shakespeare and his younger contemporaries (John Webster, John Ford, et al.). One finds basic topoi of literary Gothic in their tragedies: horror as an inescapable component of human existence; evil and villains who violate the moral norm in society; castle as a setting; fatal secret; supernatural element; motives of violence, revenge, adultery, incest and most importantly — of God and devil. Of course, Shakespeare is multiform and is not limited to Gothic. Like Shakespeare, who as a tragedian started with a “bloody tragedy” (Titus Andronicus) and then used its techniques in his great tragedies, McEwan began with a “thriller” (The Сement Garden, 1978), based on the motifs of fatal secret and incest. His later novel Nutshell (2016) is a modern version of Shakespeare’s Hamlet written in line with the realities of the 21st century. “Intertextual game” (usual for postmodernism) is not the main thing for McEwan here. Nutshell is his aesthetic-philosophical declaration of the adherence to Shakespeare’s tradition. In this novel, he creates the image of his time and shows that civilization has achieved tremendous scientific and technological success over four centuries, but human nature hasn’t changed. Despite all the historical and sociocultural differences, the image of the world in McEwan’s novels is similar to the world of Shakespeare’s tragedies — cold, full of horror and death, abandoned by God.
“I Will Bear Witness That I Remember”: The Novel Umschlagplatz by J.M. Rymkiewicz
Authors:   Institute of Slavic Studies of the Russian Academy of Sciences, Adelgeim Irina E.
Published: September 2024

The article analyses the novel Umschlagplatz (1988) by a significant Polish writer and literary critic, J.M. Rymkiewicz, which deals with a twice iconic space (Warsaw’s Umschlagplatz — pars pro toto of the Holocaust and the painful problem of Polish- Jewish relations during and after the Second World War). The article aims to determine the novel’s place in the ongoing debate in Polish society about Polish complicity in the Holocaust since the second half of the 1980s. The analysis of the complex text construction covers the relationship between poetics and the problem of testimony, the modality of fiction. Generated by an acute sense of the blatant non-presence of the space of the Jewish tragedy in Polish historical consciousness as a place of memory, guilt, and shame, Rymkiewicz’s novel appears as a postulate of commemoration and empathy addressed to Polish society, a call for recognition and comprehension of the traumatic past. Umschlagplatz was a significant artistic and ethical step in preparation for working through the Holocaust-related Polish trauma, complicated by the persistence of the heroic-romantic self-identification of Polish society.
“Masha,” a Story by B.K. Zaitsev: Composition and Idea of Order of Estate Life
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Andreeva Valeria G.
Published: September 2024

The article comprehends the structure of the story by B.K. Zaitsev’s “Masha” (1915) as a parallel development and non-linear comparison of two storylines dedicated to the love stories of the noblewoman Lisa and her peer, the peasant girl Masha. The author of this article explained the writer’s choice of the story’s title (after the name of the peasant heroine, which marks the semiotic shifts in the “estate culture” of the Silver Age). The article examines in detail the dichotomy of order / disorder, which substantially organizes the artistic world of the work. The research explores the ways of representing the “estate topos” and analyses the sociocultural connection of the heroines with the estate. The Kochki and Radishchevo estates described in the story are also characterized as two varieties of “estate topos” in Russian literature at the turn of the 19th–20th centuries. There is a typological similarity between Liza Andreeva in Zaitsev’s story “Masha” and Liza Kalitina in the novel by I.S. Turgenev, Home of the Gentry (1858). It indicates Zaitsev’s reception of Turgenev’s characterological principles in the dual portrayal of the heroines. The article identifies and classifies the details of everyday estate life in Zaitsev’s story and highlights the author’s complex, ambiguous attitude towards characters leading a secluded estate existence.
Museum Estate in Russian Literature: Narratological Aspect
Authors:   Russian State University for the Humanities, Agratin Andrey E. ,   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences
Published: September 2024

In the 20th century, the estate became a phenomenon of the historical past. This process began at the turn of the 19th and 20th century: the ghostliness of the estate culture and its archaic character are commonplace in literature of that time (A.P. Chekhov’s “The Cherry Orchard,” G.I. Chulkov’s “The Sister,” S.M. Gorodetsky’s “Sutulov’s Nest,” A.M. Kuzmin’s “The Deceased in the House”). At the same time, the problem of narrative ordering of numerous events and persons connected with the estate heritage comes to the fore. In the works of the first half of the 20th century, it appears as the aspect of comprehension of the pre-revolutionary epoch (N. Ognev’s “Kostya Ryabtsev’s Diary,” M.M. Prishvin’s “The Worldly Cup,” I.A. Bunin’s “The Imminent Spring”). But the wider the museification of the estate spreads, the more urgent becomes the question of memory narratives as a specific mechanism of cultural self-consciousness. The article analyzes S.D. Dovlatov’s story “Reserve” through the terminology paradigm of contemporary narrative theory. The writer shows how to acquire a frankly artificial (simulative) character in the estate museum context memory narratives, the “alien” estate past never becomes “his”/“her own” present of the narrator (guide) and his addressee (tourist).
TARİHÖNCESİ ÜRETİMDE ÖZELLEŞEN BİR İÇ BATI ANADOLU YERLEŞİMİ: SON BULGULAR IŞIĞINDA İLK KALKOLİTİK DÖNEM KANLITAŞ HÖYÜK
Authors: Türkcan Ali Umut
Published: September 2024

Porsuk Kültürü’nün tespit edilen en iyi korunmuş höyüğü olan Kanlıtaş Höyük (Eskişehir/İnönü), kuzeybatı Anadolu’da dağlık ve ormanlık alanın sınırındadır. Höyükte bulunan arkeolojik malzemenin genel değerlendirmesinde, höyüğün en erken MÖ 6. Bin sonu Erken Kalkolitik Dönem ve İlk Tunç Çağı II dönemlerini yansıtan bir yerleşimin varlığı öngörülmektedir. 2013 yılından itibaren başlatılan kazı çalışmalarında, höyüğün tepe kesiminde belirlenen üç 10.00 x 5.00m açmalarda yatayda 150m2 bir alan ve dikeyde 2.00m’ye ulaşan sondajda bir tabakalanma ortaya çıkarılmıştır. Bu sayede, tepe kesiminin kuzeybatısında, sondajdaki bu kompleks yerleşim dolgularının altında yerleşmenin en erken tabakası ve anakaya ile olan ilişkileri ortaya koymuştur. Daha önceden kazılan Orman Fidanlığı yerleşmesinden de bilinen mermer malzemeden yapılan halka biçimli bilezikler idi. Genelinde manyezitten yapılan üretim aletlerinin de ortaya çıktığı bu aletler ve yüzlerce işlenme aşamasında ve ıskarta olmuş mermer bilezik örnekleri ile Kanlıtaş’ın bir mermer bilezik üretim merkezi olduğunu daha açık ortaya koymaktadır. Mermer bileziklerin yapım teknolojilerini bütün aşamalarının bugüne kadar örneklerine az rastlanır alet tipleri ile beraber gelmesi ile Anadolu’da aletleri ile bütün üretim zinciri tespit edilmiştir.
Evaluating the Impact of Workplace Interventions on Employee Stress Management: Insights from Health Awareness Programs, Job Redesign and Recreation Centre Access
Authors: Hasin Hanafiah , Jamil Anita , Sari Vita Fitria , Johari Yang Chik
Published: September 2024

Workplace stress is a growing concern, with serious implications for employee well-being and organizational performance. This study examines the impact of various workplace interventions on employees' ability to manage stress, such as health awareness programs, vacation and holiday trips, job redesign, recreation center access, and social support systems. This study used a cross-sectional research design; data were collected through a structured questionnaire and analyzed using logistic regression. The results reveal that health awareness programs and access to recreation centers significantly improve employees' stress management. Job redesign showed a marginally significant effect, while vacation trips and social support systems did not significantly influence stress management. These findings highlight the importance of targeted interventions in supporting employees' mental health and reducing stress, particularly through health awareness initiatives and access to recreational facilities. Organizations should focus on these strategies while further exploring the potential benefits of job redesign and the quality of vacation policies.
Leadership Soft Skills, Perceived Trustworthiness and Structural Empowerment: A Correlation
Authors: Md Shahid Siti Asiah , Harun Shariff
Published: September 2024

To generate trust inside organizations, administrators with soft skills must build relationships and alliances with their staff, as well as create work conditions that empower employees to carry out their responsibilities. Administrators must essentially boost perceptions of trustworthiness. To solve this shortcoming, educational administrators must be informed and cautious about the notions of soft skills, dependability, and structural empowerment. This article investigates the relationship between each component of leadership soft skills, structural empowerment, and perceived trustworthiness. The mediating function of structural empowerment in the link between leadership soft skills and the perceived trustworthiness of the Head of Faculty was also investigated. This study collects its quantitative data using a survey questionnaire. The survey included 225 respondents who worked as administrative professionals in clerical and office assistant positions at three major campuses of Malaysian public higher education institutions in Malaysia's northern state. The study found that perceived trustworthiness and structural empowerment were substantially connected to all eight components of leadership soft skills. However, structural empowerment did not act as a bridge between leadership soft skills and perceived trustworthiness.