bluuebunny/crossref_metadata_2025 huggingface dataset:
Respons dua generasi tomat mutan insensitif etilen Sletr1-2 terhadap cekaman kekeringan
Authors: Rahmat Bayu Pradana Nur , Wicaksana Noladhi , Mubarok Syariful , Ramadhan Muhamad Joddy , Putri Maura Zhafira , Ezura Hiroshi
Published: April 2021

Abstrak. Buah tomat tergolong ke dalam golongan buah klimaterik. Umur simpan buah tomat sangat dipengaruhi oleh keberadaan etilen. Tomat mutan NIL Sletr1-2 adalah generasi baru dari tomat insensitif etilen. Buah dari tomat mutan NIL Sletr1-2 memiliki umur simpan yang lebih lama dari tomat komersial pada umumnyanamun kehilangan fungsi untuk merespon keberadaan etilen dapat berpengaruh kepada pertumbuhan dan perkembangan tanaman, khususnya dalam kondisi cekaman. Tujuan dari penelitian ini adalah untuk mengetahui efek cekaman kekeringan terhadap dua generasi tomat mutan insensitif etilen (NIL Sletr1-2 dan BC3F1 Sletr1-2), dengan tomat ‘Intan’ sebagai tanaman kontrol. Ketiga tomat tersebut disiram dengan tiga interval waktu yang berbeda, yaitu: setiap hari (kondisi normal), interval tiga hari (cekaman kekeringan moderat), dan interval lima hari (cekaman kekeringan berat). Hasil penelitian menunjukkan bahwa dalam kondisi cekaman kekeringan moderat dan berat, respons morfologis (tinggi tanaman, jumlah daun, dan panjang akar), dan anatomis (jumlah sel epidermis) kedua generasi tomat mutan lebih buruk dari tetuanya tomat ‘Intan’. Hal tersebut menunjukkan bahwa berkurangnya sensitivitas etilen meningkatkan kerentanan tanaman dalam kondisi cekaman kekeringan, sekaligus memperkuat anggapan bahwa etilen berperan penting dalam ketahanan tanaman terhadap cekaman lingkungan.Kata kunci: Cekaman kekeringan, Etilen, Insensitivitas etilen, Tomat mutan Abstract. Tomato belongs to climacteric fruits, Its fruit shelf life is highly affected by the presence of ethylene. NIL Sletr1-2 tomato is a novel generation of an ethylene insensitive mutant. Its fruit has prolonged fruit shelf life, lasting longer than commercial ones. However, the loss of function in ethylene response would affect plant growth and development, especially under stress conditions. The objective of this research was to investigate the effect of drought stress on two generations of ethylene insensitive tomato mutants (NIL Sletr1-2 and BC3F1 Sletr1-2), with ‘Intan’ as a control plant. Those tomatoes were watered at three different intervals: every day; three days interval; and five days. The results showed that under three and five days watering interval, both generation of ethylene insensitive mutants have reduction in plant morphological response (plant height, number of leaves, and root length) and anatomical response (epidermal cell count), compared to their control, ‘Intan’. These results indicated that reduction in ethylene sensitivity could increase plant susceptibility under drought stress condition, thus solidifying the importance of ethylene in plant defence against environmental stress.Keywords: Drought stress, Ethylene, Ethylene receptor, Tomato mutant
La sombra de Heidegger y Nietzsche. Recordando a Franco Volpi (1952-2009)
Authors: Campioni Giuliano , Volpi Franco
Published: April 2021

La influencia de Nietzsche en el pensamiento de Heidegger es notoria. Tal vez uno de los filósofos que con más perspicacia ha señalado ese impacto de una manera lúcida y sin estridencias haya sido Franco Volpi. Poco antes de morir, y con motivo de la publicación de la traducción italiana de la obra de Heidegger Contribuciones a la filosofía, dejaba clara su posición frente a Heidegger, interpretando de una manera crítica, pero ecuánime, el gran peso de la filosofía de Nietzsche en su camino del pensar. Este juicio de Volpi da que pensar y nos obliga a reflexionar sobre la filosofía de Heidegger sin perder de vista la zozobra que experimentó su filosofía en el «mar del Ser» ante el impacto que produjo en sus mamparas el reto nunca superado de la filosofía de Nietzsche.
Así ama un amigo a su amigo
Authors: Rivero Weber Paulina
Published: April 2021

En este artículo se considera que la relación de identidad construida por Nietzsche entre el amigo y el enemigo es uno de los aspectos más polémicos de su pensamiento. Para introducir este tema se exponen las ideas de dos de los pensadores que influyeron en él a este respecto, para luego analizar el sentido en que desde esta filosofía el amigo es un enemigo para el así llamado «hombre de conocimiento». A continuación se lleva a cabo un análisis de algunas ideas de Jacques Derrida y de Paul van Tongeren en torno al tema de la amistad Nietzscheana, así como una meditación en torno a la distinción entre el amigo/enemigo y el amigo/camarada. Finalmente se expone un cuestionamiento acerca de la ausencia de la amistad compasiva y de la compasión en general en la obra Nietzscheana.
Nietzsche y Epicuro
Authors: Garcia Gual Carlos
Published: April 2021

Las numerosas citas de Epicuro en diversos textos de Nietzsche expresan bien sus simpatías claras hacia la persona y la doctrina del viejo filósofo ateniense. Tanto por su oposición al espiritualismo cristiano como por ser una llamada serena a una felicidad terrestre y fácil, Epicuro le resulta un maestro amable y próximo.
La función de la metáfora en la aproximación de las cuestiones políticas en Nietzsche
Authors: Da Silva Júnior Ivo
Published: April 2021

Mediante un análisis del capítulo «Pueblos y patrias» (§§ 240-256) de Más allá del bien y del mal, pretendo poner de manifiesto la manera en que Nietzsche lleva a término su crítica al nacionalismo como algo opuesto a la unidad europea, asumiendo como referencia la música alemana, especialmente la wagneriana, la cual, en este caso, contiene una cosmovisión basada en un ideal de formación (Bildung) prácticamente inexistente en la Alemania contemporánea del filósofo. De este modo pretendo enfatizar el hecho de que la política no puede ser tomada como una metáfora para describir «estados del alma», sino que debe ser entendida en su dimensión real.
Distancia y combate: la (in)actualidad de Nietzsche
Authors: Marton Scarlett
Published: April 2021

Con este trabajo pretendemos explorar los diferentes sentidos que Nietzsche atribuyó al término unzeitgemäss en sus textos. En un primer momento, queremos mostrar que Nietzsche no se limita a resaltar el carácter inactual de su pensamiento, sino que además quiere dar a conocer la tarea que se propone. A continuación, queremos mostrar que, en ciertos pasajes, al servirse del término, el filósofo no se restringe a sublimar el carácter póstumo de sus escritos, sino que insiste en su búsqueda de un lector ideal.
La importancia de Nietzsche para las vanguardias de la arquitectura
Authors: Ruíz Salvatierra Arturo J.
Published: April 2021

Las vanguardias artísticas tomaron el pensamiento nietzscheano más sólido, aquel que representaba Zaratustra, y trataron de buscar las nuevas reglas del arte. Se trataba de vencer todo lo que los críticos del arte y los historiadores habían venido inculcando hasta ese momento. Para ello, el artista debía vencer la saturación de formas a la que se venía asistiendo a finales de siglo. Nada de eclecticismo; el nuevo arte debía arrancar desde cero.
Sobre la Tercera consideración intempestiva y el Estado griego: la crítica político- cultural de Nietzsche a la modernidad
Authors: Esteba Enguita José Emilio
Published: April 2021

El propósito fundamental de este artículo es mostrar la intempestividad del joven Nietzsche como una crítica cultural y política a la modernidad a partir del análisis e interpretación de dos textos fundamentales de este periodo en lo que respecta a la mencionada crítica: Consideraciones intempestivas III: Schopenhauer educador y El Estado griego.
Génesis, Parodia y modernidad en «Así habló Zaratustra»
Authors: D'Iorio Paolo
Published: April 2021

El análisis de los cuadernos escritos en Sils-Maria en el verano de 1881 nos proporcionan indicaciones precisas sobre la génesis de Así habló Zaratustra: sobre la relación entre Zaratustra y el eterno retorno, sobre la naturaleza paródica de la figura del sabio persa y sobre los lazos estrechos que lo une a la filosofía y a la literatura de la época de Nietzsche. Bajo la lente del filólogo y a través del prisma de la biblioteca y de las lecturas de Nietzsche, lo que parecía serio y arcaico llega a ser paródico y moderno.
Mediodía. Del sentido del presente en el pensamiento
Authors: Mateos de Manuel Victoria
Published: April 2021

En este artículo sostengo que la contraposición nietzscheana entre pensamiento —espíritu de la pesadez— y vida —bailes ligeros, pies de muchachas de hermosos tobillos— está articulada en torno a la cuestión de la temporalidad y el ritmo. Esta tensión metafórica que aparece en Así habló Zaratustra contiene la idea de la imposibilidad de la filosofía para sincronizarse con el mundo de la vida y, por tanto, de acontecer simultáneamente a la existencia. A lo largo de su obra, Nietzsche  plantea dos posibles tiempos anacrónicos del pensamiento. En primer lugar, la filosofía es siempre pasado: queda como dación de sentido póstumo a la existencia o intensificación ulterior de lo vital. En segundo lugar, el pensamiento es muro de contención a través del tiempo de la inminencia, como plantea su inicial dionisismo filtrado por lo apolíneo. En Así habló Zaratustra, frente a estos dos modos de desfase del pensamiento en relación a lo vital, Nietzsche aporta una nueva propuesta articuladora del tiempo en la filosofía y la posibilidad de su presente: el presente del pensamiento no es el presente de la escritura, sino el de su actualización en la lectura —el país de los hijos—.
El eterno retorno de lo mismo, «el pensamiento fundamental de Zaratustra»
Authors: Marton Scarlett
Published: April 2021

En Ecce Homo, Nietzsche establece que la concepción básica de Así habló Zaratustra consiste en «la idea del eterno retorno, la más alta fórmula de la afirmación que puede ser alcanzada posiblemente». Tomando como punto de partida el análisis de las diferentes partes de este libro, trataremos en primer lugar de definir el lugar del pensamiento del eterno retorno. Al establecer la relación de este pensamiento con la noción de superhombre, el concepto de voluntad de poder, el proyecto de la transvaloración de los valores y la idea del amor fati, tratamos de examinar el modo en que Nietzsche lo concibe en Así habló Zaratustra. A continuación, tratamos de evaluar en qué medida el pensamiento del eterno retorno en la más alta aceptación del mundo tal como es.
Compasión, temor y catarsis. La lectura nietzscheana de Aristóteles
Authors: Abad Alfredo
Published: April 2021

Desde El nacimiento de la tragedia hasta los Fragmentos póstumos del último periodo, Nietzsche alude a la especificación aristotélica de los efectos trágicos y la catar sis con un categórico rechazo. Sin embargo, estos planteamientos no  necesariamente se deben identificar como válidos, al menos en lo concerniente al sentido atribuido a las percepciones aristotélicas que están principalmente contenidas en la Poética. El texto ilustra las referencias establecidas por Nietzsche con el fin de esclarecer su manifiesto crítico y plantear algunos interrogantes sobre la legitimidad de sus objeciones, teniendo presente el derrotero preceptivo de Aristóteles en su libro sobre la tragedia.
Revistas monográficas sobre Nietzsche
Authors: Amaya Carlos
Published: April 2021

Estas páginas recogen las revistas monográficas sobre Nietzsche publicadas en 2016.
Wotling, Patrick, «Oui, l’homme fut un essai»: La philosophie de l’avenir selon Nietzsche, Paris: Presses Universitaires de France, 2016
Authors: Ruíz Ortíz José Honorio
Published: April 2021

Reseña de la obra Wotling, Patrick, «Oui, l’homme fut un essai»: La philosophie de l’avenir selon Nietzsche, Paris: Presses Universitaires de France, 2016
Investigar con Nietzsche en español hoy
Authors: Rodríguez González Mariano
Published: April 2021

Con un ejemplo concreto, el de la experiencia de mi actual investigación sobre Nietzsche como filósofo de la mente y psicólogo filosófico, este trabajo procederá a mostrar algunas de las grandes ventajas que le está reportando el hecho de tener ya a nuestra disposición la obra y los fragmentos póstumos completos en lengua española, editados bajo los auspicios de la SEDEN por el equipo dirigido por Diego Sánchez Meca.
Gori, Pietro, Nietzsche y el perspectivismo, Córdoba (Argentina): Brujas, 2017
Authors: Luque Moya Gloria
Published: April 2021

Reseña Gori, Pietro, Nietzsche y el perspectivismo, Córdoba (Argentina): Brujas, 2017
Nasser, Eduardo y Rubira, Luís (coords.), Nietzsche no século xxi, Porto Alegre (Brasil): Zouk, 2017
Authors: Luque Moya Gloria
Published: April 2021

Reseña de la obra Nasser, Eduardo y Rubira, Luís (coords.), Nietzsche no século xxi, Porto Alegre (Brasil): Zouk, 2017
Strauss, Leo, On Nietzsche’s Thus Spoke Zarathustra, ed. de Richard L. Velkley, Chicago y Londres: The University of Chicago Press, 2017
Authors: Lastra Antonio
Published: April 2021

Reseña de la obra Strauss, Leo, On Nietzsche’s Thus Spoke Zarathustra, ed. de Richard L. Velkley, Chicago y Londres: The University of Chicago Press, 2017
Informe Bibliográfico: Nietzsche y el nihilismo
Authors: Alvarado Díaz Cristina
Published: April 2021

Estas páginas recogen un informe bibliográfico sobre Nietzsche y el nihilismo
Novedades bibliográficas
Authors: Rovi Ruíz Antonio
Published: April 2021

Estas páginas recogen las novedades bibliográficas sobre Nietzsche publicadas en 2018.
Rodríguez, Mariano, Más allá del rebaño. Nietzsche, filósofo de la mente. Madrid: Avarigani, 2018. 335 pp.
Authors: Barrios Ferén
Published: April 2021

Reseña: Rodríguez, Mariano, Más allá del rebaño. Nietzsche, filósofo de la mente. Madrid: Avarigani, 2018. 335 pp.
La soledad enamorada
Authors: Zambrano María
Published: April 2021

Si ha habido un hombre de muchas y contradictorias personalidades, desgarrado por la desbordante riqueza, por la punzante contradicción, es, sin duda, Nietzsche, tan amado y repudiado, tan olvidado y presente. Nietzsche representa hoy, al cabo de su muerte, el calvario de la soledad apurada hasta lo último, sorbida con estoica crueldad, llevada hasta más allá de todo lindero visible. Este artículo publicado por primera vez en la revista Universidad Michoacana explora la soledad intelectual en la figura de Nietzsche.
El Nietzsche de Zambrano
Authors: Maillard García María Luisa
Published: April 2021

La filosofía de María Zambrano mantiene un diálogo ininterrumpido con Nietzsche, es decir, con el nihilismo contemporáneo. La comprensión de la vida como continua transformación, es una idea que ambos filósofos comparten, así como el amor, la pasión por el hombre; pero les van a separar una diferente concepción del tiempo y una diferente comprensión de lo sagrado. Seducido por lo divino, Nietzsche no supo descubrir el fondo del que surge lo divino, lo sagrado. Éste se basa en el tiempo y el tiempo es la resistencia implacable que la vida opone al delirio de deificación.
Música y palabras en Nietzsche: Sobre la cuestión de la ciencia, el estilo y la música de la tragedia griega antigua
Authors: Babich Babette E.
Published: April 2021

Partiendo de un análisis de la condición póstuma de la obra nietzscheana, el trabajo desentraña las características peculiares de su estilo, por las que pensamiento y lenguaje se hallan imbricados de tal manera que cada obra nietzscheana está construida calculando muy cuidadosamente los efectos que puede producir en los diversos tipos de lectores. De aquí que el trabajo reexamine también las distintas formas básicas de leer y considerar a Nietzsche, alejándose de los dos extremos representados por la tendencia historicista dedicada a resaltar las influencias en la obra nietzscheana, y por la tendencia retoricista que insiste en considerar su obra como un puro juego metafórico. La autora encuentra la mejor vía hermenéutica en la consideración que hace el mismo Nietzsche de cómo debemos leer la tragedia griega antigua: ‘oyendo con  nuestros ojos’, es decir, buscando la música que hay detrás de las palabras.
La poetización nietzscheana del lenguaje y del pensamiento
Authors: Conill Jesús
Published: April 2021

A partir de la genealogía del lenguaje y su carácter tropológico (metafórico), mi propósito consiste primero en exponer ciertas aportaciones de la interpretación semiótica del pensamiento nietzscheano, que ha conducido hasta una ‘filosofía del signo’, pero sobre todo en mostrar que su sentido más profundo es el hermenéutico y en defender que en el contexto nietzscheano lo decisivo radica en un originario dinamismo poetizador del lenguaje y del pensamiento.
La crítica de Nietzsche al Romanticismo
Authors: Ávila Crespo Remedios
Published: April 2021

Este artículo pretende mostrar la evolución de la concepción nietzscheana del romanticismo y considerar la actualidad de sus reflexiones. Para ello, propone un recorrido en tres partes: en primer lugar, examina el “malentendido” de su primera obra; en segundo lugar, considera los elementos que conducen a Nietzsche a comprender el romanticismo como una enfermedad. Finalmente, explora, de la mano de Nietzsche, el camino hacia la salud.
Nietzsche y la idea romántica de una ‘nueva mitología’
Authors: Sánchez Meca Diego
Published: April 2021

La razón se compone de conceptos y reglas de operación y los conceptos son configuraciones y síntesis: consiguen reunir en una unidad, bajo ciertos puntos de vista, la pluralidad de la realidad sensible. Esta reunión de la pluralidad en la unidad (en un concepto válido para clases de objetos o contextos) es una actividad productiva, una ficción o invención de la imaginación. El más antiguo programa del Idealismo Alemán afirmaba que la razón es resultado de la imaginación. Y Nietzsche desarrollará esta idea en su temprano estudio Sobre verdad y mentira en sentido extramoral. Con todo, sus semejanzas y diferencias con el romanticismo y con el idealismo deben ser muy cuidadosamente matizadas.
Epistolario de Nietzsche: Aparato crítico 1887-1889
Authors: Morillas Antonio
Published: April 2021

Espacio dedicado a revisar la publicación de los comentarios críticos o Nachberichten al epistolario de Nietzsche editado en la edición Colli-Montinari (KGB)
Los manuscritos póstumos desde 1885 en trascripción diferenciada: vol. IV
Authors: Morillas Antonio
Published: April 2021

Espacio dedicado a revisar el volumen IV de los manuscritos póstumos desde 1885 en trascripción diferenciada.
Maldonado, Rebeca, Metáforas del abismo. Itinerarios de ascenso y descenso en Nietzsche
Authors: De Santiago Guervós Luis Enrique
Published: April 2021

Recensión crítica de la obra Maldonado, Rebeca, Metáforas del abismo. Itinerarios de ascenso y descenso en Nietzsche
Nietzsche descubre a Dostoievski. Notas sobre la lectura nietzscheana de la patrona
Authors: Llinares Joan B.
Published: April 2021

Exposición del descubrimiento de la obra de Dostoievski por parte de Nietzsche, que tuvo lugar a finales de 1886 o comienzos de 1887, gracias a la lectura de L’esprit souterrain, curiosa versión francesa de dos textos del escritor ruso, la novela de juventud La patrona y una adaptación del relato de madurez Memorias del subsuelo. Siguiendo el magisterio de Joseph Frank y la senda abierta en 1973 por C. A. Miller, se argumentan algunas razones que motivaron la estima nietzscheana por aquella novela y su presentación como una pieza de música, muy extraña y muy poco alemana.
¿Hay que incorporar a nietzsche a la hermenéutica? Razones de una pequeña resistencia
Authors: Grondin Jean
Published: April 2021

El tema del lugar de Nietzsche en la hermenéutica implica varias cuestiones: ¿el pensamiento de Nietzsche puede ser caracterizado como «hermenéutico»?, y ¿en qué medida, dado que la hermenéutica sólo ha sido desarollada como tal después de él? ¿Puede y debe la hermenéutica, que hasta hace poco no ha tenido muy en cuenta su pensamiento, incorporarlo todo entero? Si bien una fecundación mutua sería siempre fructífera, este trabajo defiende que deberíamos resistir frente a una integración simple en la hermenéutica, teniendo en cuenta su diferente manera de entender la verdad, la interpretación y el nihilismo. De este modo también se hace posible una resistencia frente a la concepción postmoderna y nihilista de la hermenéutica. Siendo conscientes de sus diferencias, la hermenéutica y Nietzsche tendrían mucho que contribuir uno a otro.
Sedative Effect and Standardization Parameters of Herbal Medicinal Product Obtained from the Ocimum americanum L. Herb
Authors: Shanaida M. , Golembiovska O. , Jasicka-Misiak I. , Oleshchuk O. , Beley N. , Kernychna I. , Wieczorek P.P.
Published: April 2021

Sedative phytomedications continue to play an important role in the management of a considerable amount of anxiety symptoms because of the various side effects of synthetic sedatives and tranquilizers. However, developing new herbal drugs needs their appropriate quality control according to the relevant requirements. The aim of the study was to determine the sedative properties of the tinctures obtained from the American basil (Ocimum americanum L., Lamiaceae Martinov family) herb and to develop the standardization parameters for the promising herbal medicinal product. The open field test was used to evaluate the sedative effect of the prepared tinctures: (1) with the added of O. americanum essential oil (OATEs) and (2) without adding O. americanum essential oil (OAT). The standardization parameters for the OATEs were developed using validated High-Performance Thin Layer Chromatography (HPTLC) and High-Performance Liquid Chromatography (HPLC) methods. The HPTLC analysis was used for the chromatographic fingerprints of polyphenols and for identifying linalool in the OATEs. The HPLC analysis found the significant content of rosmarinic acid (RA) (0.26%) in the OATEs. In conclusion, the developed OATEs can be considered as the new herbal medicinal product with significant sedative properties.
Applications of the extended rational sine-cosine and sinh-cosh techniques to some nonlinear complex models arising in mathematical physics
Authors: Akkılıc Ayse Nur , Sulaiman Tukur Abdulkadir , Bulut Hasan
Published: April 2021

This study presents the applications of the extended rational sine-cosine/sinh-cosh schemes to the Klein-Gordon-Zakharov equations and the (2+1)-dimensional Maccari system. Various wave solutions such as singular periodic, periodic wave, topological, topological kink-type, dark and singular soliton solutions are successfully revealed. To display the physical features of the reported solutions, we use some appropriate choice of parameters in plotting the 3D, 2D, and contour graphs of some attained solutions.
Some Existence Results for Systems of Impulsive Stochastic Differential Equations
Authors: Mekki Sliman , Blouhi Tayeb , Nieto Juan J. , Ouahab Abdelghani
Published: April 2021

In this paper we study a class of impulsive systems of stochastic differential equations with infinite Brownian motions. Sufficient conditions for the existence and uniqueness of solutions are established by mean of some fixed point theorems in vector Banach spaces. An example is provided to illustrate the theory.
A Review on the Performance and Comfort of Stab Protection Armor
Authors: Sitotaw Dereje Berihun , Ahrendt Dustin , Kyosev Yordan , Kabish Abera Kechi
Published: April 2021

Stab-protective clothing is the most important component of safety equipment and it helps to save the lives of its wearers; therefore, it is designed to resist knife, nail, or needle attacks, especially to the upper body. In this paper, the essential requirements for stab-resistant armor are investigated based on an in-depth review of previous research and prototype test results. The combination of protection and comfort in armor vests is a particularly challenging task. Review of the state of the art technology responsible for the manufacture of stab-resistant clothes has revealed that their design and development should encompass the elements of comfort, freedom of movement, permeability, absorption, evaporation, and weight reductions to ensure excellent ergonomics and high wear comfort. The design as well as the production, weight, thickness, material types and properties, and the arrangement of scales determine the level of protection and comfort offered by stab-resistant vests. Currently, the production of stab-proof gear-based 3D printing technology is evaluated, using lightweight materials (aramid) in the form of segmented scales inspired by nature. As the protection performance and wear comfort of stab-proof gear is enhanced, the willingness of security, control, transport, custom, and correction officers to wear them can be significantly increased in an endeavor to ensure that fatal injuries will decrease significantly.
Analysing Service Quality and Its Relation to Customer Satisfaction and Loyalty in Sportswear Retail Market
Authors: Saricam Canan
Published: April 2021

The sportswear industry has a growing market globally. In the sportswear retail market, where the primary focus is on providing customers the product, but provision of the necessary ancillary service also takes place, the service quality and its relation to customer satisfaction and customer loyalty are important. With an attempt to find out this relationship, the data for this study was obtained from 251 people living in Turkey. The service quality was described as a second-order construct with the dimensions proposed in SERVQUAL scale. Confirmatory factor analysis and structural equation modeling were used to analyze and validate the model. The findings showed that the service quality, together with the relevant dimensions, tangibles, reliability, and assurance, has an influence on the customer satisfaction but not on the customer loyalty. Nonetheless, it was confirmed the customer satisfaction has an impact on the customer loyalty.
Rethink about the role of rheumatoid factor and anti-citrullinated protein antibody in rheumatoid arthritis
Authors: Sung Wang Yu , Tsai Wen Chan
Published: April 2021

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by joint inflammation and extra-articular manifestations. Many questions in the pathogenesis, clinical manifestation, and disease spectrum are answered after the discovery of the first autoantibody namely rheumatoid factor (RF). The finding of the second autoantibody named anti-citrullinated protein antibody (ACPA), which unearths the importance of protein citrullination process. It further provides the insight how immune cells and complement interact to perpetuate the inflammatory response. These two autoantibodies pave the way for our better understanding of RA. This review article focuses on the history, pathophysiology, and clinical association of these two autoantibodies in RA.
The Glass Wall of Opera Houses
Authors: O'Connor Parker
Published: April 2021

In the twenty-first century, many argue that Opera is a dying art form and no one wants to see an opera. However, since 2000 many opera houses have been built around the world in centres without longstanding traditions of opera. As a result architects are now forced to balance the centuries of traditions of opera with a contemporary audience. Architect and city developers have begun to think of inventive ways to use architecture of opera houses as a lure to attract those who might not typically attend the opera. The act of going to the opera begins with the transportation chosen to get there, followed by interaction with the public spaces outside, through the doors into the public lobby, and finally into the auditorium. The opera house can be a space that people do not only go to see a performance but to feel like a part of a community. This integration is developed through the architecture of the opera house and, in particular, the choice of material of glass in many contemporary opera houses. This relationship of community inside versus outside the opera house is permeable through this glass wall. Understanding the opera house as a creator of community allows for opera to remain an integral part of culture moving further into the twenty-first century.
Hogarth and Bad Taste: The Sculptures at St. Bartholomew’s as Satirical Inspiration
Authors: Revell Timothy
Published: April 2021

The engraving Masquerades and Operas (1724), also known as The Bad Taste of the Town, was William Hogarth’s first self-published work. Despite this milestone, it has become a footnote to more studied works such as The Rake’s Progress. I have discovered that Hogarth used sculptures from the Henry VIII Gate at St. Bartholomew’s Hospital in London on his depiction of the Great Gate of Burlington House (home to the Royal Academy of Arts); I believe this is an overlooked element of the print that signals his distaste for foreign art. Hogarth strongly opposed Italianate painting and architecture, even painting frescoes at St. Bartholomew’s gratis, after learning the commission had gone to an Italian. Through visual, political, and contextual analysis, I argue that allusions to Raphael and Michelangelo in Masquerades and Operas associate Italian art with “lameness” and “disease” and are meant to show the decadence of Italian art and its impact on the arts in England. Their position on the Henry VIII Gate further alludes to the malignancy of the aristocracy, whom Hogarth saw as adversely affecting British culture by adopting foreign influences.

The Brexit vote and global political turmoil are at the forefront of today’s political situation. In this regard, it is valuable to look back at times of significant cultural change and examine why artists like Hogarth, and contrastingly, Hogarth’s nemesis William Kent (a proponent of classical architecture inspired by Italian examples), strove for and against intercultural exchange.
The Human-Machine: Possibilities for Expression in Robotic Dance
Authors: Brown Hannah M.
Published: April 2021

Robots have been a source of both intrigue and anxiety for artists and a lively apparatus for study by scientific researchers for several decades. Though many people view robots as being cold, unemotional, and frightening, there is a growing field in robotics specifically focused on social applications including therapy, elder care, and the arts. Robots have been utilized extensively in installation art works and sculpture, but the performing arts have been somewhat more resistant to them. Machines which have all the technical abilities to perform tasks, such as playing an instrument or executing choreography without fatiguing or making errors, can be threatening to human performers who have honed these abilities and rely upon them for creative expression and their livelihoods. By synthesizing studies in the scientific field of social robotics, philosophical insight into technology and the arts, and case studies of robots used in dance and other art forms, I seek to provide an alternative point of view of robotic integration into performance. Robots do not need to act only as avatars of human beings, they can be effectively utilized in dance to expand upon the capabilities of the human body, act as automatic ‘puppets’ for choreography, integrate into human performance, and be ‘autonomous’ performers in their own right. Robot dancers do not inherently replace or devalue human artists; instead, they can provide complex insight into the understanding of human bodies, emotions, and technology.
How Did the Case of Jack the Ripper help the Metropolitan Police and Forensic Science
Authors: White Sandra
Published: April 2021

This study will examine the links between the historical case of Jack the Ripper, the history of forensic science, and the advancement of policing for the Metropolitan Police and forensic in Victorian Britain. Ripper’s crimes were committed in a ‘pre-forensic science’ period, when there were no fingerprints, DNA, or crime scene investigation units to help Detectives capture sophisticated criminals, but through this case forensic science and the Metropolitan Police Force would develop into a more modern form of policing. Jack the Ripper can be considered the prototype of the definition of a serial killer, and his crimes were of a nature that police had little experience with, which meant the police force would have to develop new techniques in criminal investigation. This study will examine the early history of the Metropolitan Police, how the young police force—less than sixty years old by the first murder of Jack the Ripper—was organized, the tools available for investigating murders, how the case of Jack the Ripper led to advancements in criminal investigation and how these new techniques were used to solve other crimes. The Metropolitan Police and British pathologists—such as Dr. Bernard Spilsbury— developed new ways of catching criminals because of the Jack the Ripper case, such as crime scene preservation, profiling and the use of photography to capture crime scenes that would be used to solve the case of Dr. Crippen in 1910 and the Bathtub Murders in 1915.
Using the Talk Test to Prescribe and Guide Exercise Intensity: Speaking Your Way to Improved Fitness
Authors: Preobrazenski Nick
Published: April 2021

Introduction: The Talk Test (TT) is a non-invasive, subjective method of prescribing exercise intensity. The TT involves three stages. When exercisers can speak comfortably, can speak but not comfortably, or cannot speak comfortably, they are in the positive (POS), equivocal (EQ), and negative (NEG) TT stages, respectively. The NEG stage correlates with important physiological markers such as ventilatory threshold and lactate threshold. Given the evidence demonstrating large increases peak oxygen consumption (VO2peak) when training at intensities above these markers, the purpose of the study was to test the hypothesis that the TT is efficacious for improving VO2peak at both the group and individual level in young, healthy males.

Methods: 11 healthy males completed a maximal fitness test before and after 4 weeks of training 4 times per week for 30 minutes in the NEG stage. The TT was performed every 2.5 to 5 minutes to ensure that the resistance would be enough to elicit a NEG response. Changes in VO2peak below 2 times a previously established typical error were classified as non-response.

Results: Four weeks of training at NEG induced a significant increase (11.5%) in VO2peak (PRE: 45.80 mL/Kg/min ± 4.92; POST 51.07 mL/Kg/min ± 5.45, p < 0.001). Furthermore, only one participant (9.09%) was classified as a non-responder in VO2peak following training.

Conclusion: These results suggest that the TT can efficaciously prescribe and guide exercise intensity in young, healthy males, and that training at an intensity that prevents comfortable speech leads to a small incidence of non-response
Evaluating a Motivational Interviewing Workshop for Medical Students at Queen’s University
Authors: Skelding Sarah
Published: April 2021

Motivational interviewing (MI), a partnership-based counselling style, has increasingly been used to promote behaviour change among adults. Despite its potential to support behaviour change, there is a lack of research examining the most effective ways to train health care practitioners to use MI when working with patients. The purpose of this research was to evaluate uptake of MI skills following a one-day MI workshop that was developed in partnership with Exercise is Medicine for second year medical students enrolled at Queen’s University. The workshop focused on developing a basic understanding of the MI spirit, the phases of MI, and the ways in which MI may be used in different behavioural contexts. Participants (n=69) were asked to complete a pre and post-questionnaire that explored their knowledge of MI and their current perceptions of MI in addition to completing the Helpful Responses Questionnaire (HRQ), a validated MI assessment tool. A process evaluation was also conducted for each facilitator to measure fidelity to MI during the workshop. Results from the process and outcome evaluations are currently being evaluated. Results from this study will help determine whether a one-day workshop format is an appropriate delivery method for teaching MI techniques. Future research is needed to determine if medical students utilize information gained in their medical practice.
Predicting Chemotherapy Treatment Outcomes in Ovarian Cancer Patients Using Gene Expression Analysis
Authors: Tarnouskaya Anastasiya
Published: April 2021

Ovarian cancer is the abnormal development of cells found in the ovaries. It is the fifth most fatal cancer amongst woman and has an overall five-year survival rate of 45% (American Cancer Society, 2016). For women with newly-diagnosed, advanced stage ovarian cancer, the current standard of care is surgery – to remove as much of the cancer as possible – followed by chemotherapy – to kill the remaining tumour cells (Cancer.Net Editorial Board, 2016). However, chemotherapy can have devastating side-effects such as infection, nausea, reduced cognitive

function, and death (Sun, et al., 2005). Using patients’ genomic profiles to predict how well they will respond to the standard of care will be valuable for patients when deciding whether to pursue standard or alternative forms of treatment. This study uses ovarian cancer patient data compiled by The Cancer Genome Atlas (TCGA). Clinical data – such as patient age, gender, ethnicity, disease severity and treatment undergone – is used to define which patients responded well to chemotherapy. Patient gene expression data – which gives insight into which genes are up- or down-regulated – will be used to identify markers of chemotherapy response. This will be done using differential gene expression analysis – to identify individual genes that contribute to chemotherapy-response – and network analysis – to understand how the expression of these genes functions as a system. To make the results of the study clinically relevant, chemotherapy-response markers will be correlated to single nucleotide polymorphisms – a form of genetic variation that is much quicker to test for in a patient than gene expression.
1. A Decade of Dwarf Birch Growth across a Canadian Low Arctic Landscape: Exploring the Impacts of Climate Change
Authors: Andruko Rhett
Published: April 2021

Climate change predominantly affects northern regions, and resultant vegetation change (particularly the expansion of arctic shrubs) has the potential to create large-scale, positive climate feedbacks, including the widespread release of CO2 from arctic soils. Understanding the intensity and distribution of arctic shrub expansion is therefore necessary to predict future climate trajectories. Few studies, however, have directly measured vegetation changes in the Canadian continental low Arctic, and similarly, there is a need to better understand the landscape-level factors that determine shrub growth responses to warming. Previous studies in Alaska indicate strong differences in shrub growth responses between habitat-types, attributed to higher nutrient and water supply in low-lying areas. Therefore, this study examines growth patterns of the dominant shrub (Dwarf Birch, Betula glandulosa) in a variety of habitat-types across a low arctic landscape.

Significant increases in both shrub cover and stature over ten years were found, but surprisingly there were no differences in growth between habitat-types. Further analyses (pending) will measure inter-annual shrub growth to compare patterns/degrees of variability between habitat-types. Individual shrub growth rates over the past decade correlated to local soil nutrient concentrations, but no other variables, suggesting that local spatial variation in nutrient availability seems to be the primary factor determining shrub growth responses to climate change. Overall, our preliminary results stress the importance of local nutrient variability in controlling shrub responses to warming, and challenge previous studies indicating strong differences in shrub growth responses to warming among habitat-types.
9. Piecing Together Monumental Sites of History
Authors: Jennings Kelsey
Published: April 2021

Uncovering some of the United Kingdoms most fascinating historical sites, this interactive digital website puts on display one of the newest collections in Queen’s W.D. Jordan Special Collections Library.  Using geospatial location technology and a variety of digital humanities concepts, the project undertook the task of mapping over 700 architectural guidebooks from across the United Kingdom. A key driving factor in the creation of the site was the challenge of making collections more accessible to students; encouraging the use of the wide range of the primary source material. The website conjoins the large guidebook collection with literature found in the Schulich-Woolf rare book collection. Through a thorough investigation of the existing literature in the library, this platform connects the plethora 20th-century guidebooks with the many rare 18th, 19th, and 20th-century antiquity books featured in the Schulich-Woolf collection. Through an accessible platform, students are now able to view the guidebook collection, while being able to access key resources for further research into key pieces of British history and identity.
15. The Comparative Toxicity of two Canadian Diluted Bitumens to Developing Yellow Perch (Perca flavescens)
Authors: McDonnell Denby
Published: April 2021

Increasing demand for diluted bitumen (dilbit) has led to the development of the Alberta oil sands industry and the expansion of current and future transcontinental pipelines. However, the growth of oil transportation has led to public concern about the effects of potential dilbit spills to aquatic ecosystems. Although the toxic effects of crude oils through exposure to polycyclic aromatic hydrocarbons (PAH) are well characterized, little is known about the toxic effects of dilbit because of the variable proportions of diluent added to bitumen. Here we assessed the toxicity of the two most transported dilbits in Canada, Access Western Blend (AWB) and Cold Lake Blend (CLB) to developing yellow perch (Perca flavescens), a species distributed throughout North America. Embryos were exposed to dilbit until hatch, or up to 16 days, using a static daily renewal treatment regime of water accommodated fractions (WAF) and chemically-enhanced water accommodated fractions (CEWAF) of dilbit at total PAH (TPAH) concentration ranges of 0.02 to 10.7 μg/L and 0.21 to 20.4 μg/L TPAH, respectively. Results show that with increased TPAH concentration, the frequency of hatched embryos with developmental malformations increased proportionally. Expression of genes associated with phase I and II detoxification, cellular stress, and xenobiotic metabolism were altered in higher TPAH concentrations. This is the first study assessing the toxicity of both AWB and CLB dilbits on wild-sourced fish. With recent approvals of pipelines in North America, these biomarkers will assist risk assessments and monitoring of Canadian ecosystems should a pipeline spill occur.
Comparison of the appendicitis inflammatory response and Alvarado scoring systems in the diagnosis of acute appendicitis in children
Authors: Vaziri Mohammad ,   Department of Surgery, Hazrat-e Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran,   Department of Surgery, Hazrat-e Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran, Nafissi Nahid ,   Department of Breast Surgery, Hazrat-e Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran, Jahangiri Fariba ,   Department of Pediatric Surgery, Ali-Asghar children Hospital, Iran University of Medical Sciences, Tehran, Iran, Nasiri Mohammad ,   * Corresponding Author: Mohammad Nasiri, Department of Surgery, Hazrat-e Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. Phone: 00989121763489. E-mail: moham.nasiri@gmail.com
Published: April 2021

Our objective was to compare the diagnostic accuracy of Alvarado and appendicitis inflammatory response (AIR) scoring systems among children suspected of acute appendicitis concerning their postoperative outcomes. During a two-year period, a prospective multicentric study was carried in the selected hospitals of Iran. All children who were admitted with the diagnosis of acute appendicitis were enrolled in the study. However, patients suffering from generalized peritonitis or those who had a history of abdominal surgery were excluded. Before decision-making, each patient’s score according to two appendicitis scoring systems was calculated. The clinical outcomes and diagnosis of patients were then compared to the results of each scoring system. For those patients who were a candidate for surgery, the final diagnosis of acute appendicitis was made by histopathology. Patients were divided into a high- and low-risk group according to scoring systems outcomes. Among the patients with a low score for appendicitis, the AIR scoring system had a sensitivity and specificity of 95% and 74%, respectively, which was more promising in comparison to that of the Alvarado system (90% and 70%, respectively). Regarding the patients at higher risk of acute appendicitis, none of the scoring systems provided reliable results since both systems showed sensitivity and specificity of less than 50%, which was not sufficient to distinguish patients who are a candidate for surgery. AIR and Alvarado scoring systems are not accurate models to predict the risk of acute appendicitis among children; however, the AIR system could be used as a reliable material to rule out the acute appendicitis diagnosis.
Changes of pro- and antioxidant indicators in experimental animals under acute small bowel obstructions
Authors: Pidruchna Svitlana Romanivna ,   Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine,   * Corresponding Author: Svitlana Romanivna Pidruchna, Head of Medical Biochemistry Department, I. Horbachevsky Ternopil National Medical University, Voli Square, 1, 46002, Ternopil, Ukraine. Phone: +38(098)640-86-27. E-mail: pidruchna@tdmu.edu.ua., Benedyct Volodymyr Volodymyrovych ,   Department of General Hygiene and Ecology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine., Piatnochka Volodymyr Ivanovych ,   Department of General Hygiene and Ecology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Melnyk Nataliia Anatoliiivna ,   Department of Surgery, Institute of Postgraduate Education, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine., Mykhailivna Zakharchuk Uliana ,   Ternopil Regional Drug Treatment Clinic, Ternopil, Ukraine.
Published: April 2021

Acute small bowel obstruction remains one of the most challenging nosologies in emergency surgery, leading to a pronounced imbalance between lipid peroxidation and the antioxidant defense system. We aimed to study changes in the anti- and prooxidant status of serum and small intestine wall in an experiment modeling acute small bowel obstruction. The control group included 11 rats, and the main group included 42 rats (simulation of mechanical bowel obstruction on day 1 was conducted in 14 rats, on day 2 – in 12 rats, on day 3 – in 16 rats). Acute small bowel obstruction was modeled by ligation. Serum analysis and removal of the small intestinal wall were performed on days 1, 2, and 3. Indicators of lipid peroxidation and antioxidant protection were determined by the spectrophotometric method, and the imbalance between lipid peroxidation and antioxidant protection gradually increased from 1 to 3 days of observation. On day 3, the low level of aldehyde increased 1.3 times, and the level of superoxide dismutase decreased 1.2 times compared to the control group. Pathophysiological changes in the wall of the small intestine are caused by the activation of lipid peroxidation and the exhaustion antioxidant protection, whereby the degree of their severity increases depending on the increase in time from the moment of modeling of acute obstruction of the small intestine.