bluuebunny/crossref_metadata_2025 huggingface dataset:
Manajemen Layanan Produk Kemas Ulang Informasi Digital di PDII LIPI
Authors: Nashihuddin Wahid , Tupan Tupan
Published: February 2019

Di era globalisasi ini, pengguna jasa perpustakaan, dokumentasi, dan informasi sangat tergantung pada internet dan aplikasi teknologi digital untuk mendapatkan informasi. Begitu juga halnya dengan pengguna jasa di PDII, yang mana mereka lebih sering memesan informasi secara online dan meminta petugas untuk mengemas ulang dalam satu topik informasi. Hal tersebut guna mempermudah dan mempercepat pemanfaatan literatur untuk kegiatan penelitian atau koleksi lembaga. Secara umum, kajian ini bertujuan untuk mendeskripsikan proses pengelolaan produk kemas ulang informasi digital di PDII, yang dilihat dari aspek: (1) karakteristik pengguna jasa informasi; (2) kegiatan kemas ulang informasi; (3) jenis produk kemas ulang informasi; dan 4) proses kemas ulang informasi di PDII. Data kajian ini dijabarkan secara deskriptif, melalui hasil observasi, studi literatur, dan dokumentasi. Kesimpulan kajian ini, yaitu: (1) kemas ulang informasi digital disediakan untuk memenuhi kebutuhan pengguna PDII, baik digital immigrants maupun digital natives; (2); fungsi kegiatan kemas ulang informasi adalah untuk preservasi dan diseminasi informasi ilmiah; (3) kemasan informasi digital yang dikelola PDII adalah paket informasi  full text terseleksi dalam satu topik, dalam bentuk e-book dan pohon industri digital; dan (4)  kegiatan kemas ulang informasi digital dilakukan secara cermat dan sistematis berdasarkan permintaan pengguna.
Persepsi Pemustaka Berdasarkan Stratifikasi Sosial Pendidikan Terhadap Fungsi Perpustakaan Sebagai Tempat Penyimpanan Hasil Karya Manusia
Authors: Nurislaminingsih Rizki
Published: February 2019

Gambaran perpustakaan sebagai tempat penyimpanan buku merupakan stigma yang sulit untuk dihilangkan hingga saat ini. Kecanggihan perangkat teknologi dan internet yang ada di perpustakaan belum juga mampu mengikis paradigma perpustakaan sebagai gudang buku. Perpustakaan Kota Yogyakarta menjadi salah satu contoh perpustakaan yang tidak memiliki kesan kaku. Bangunan perpustakaan yang mirip sebuah rumah, layanan internet dan koleksi audio visual membuat perpustakaan tersebut menjadi tempat belajar yang menyenangkan. Hal ini sangat dibutuhkan oleh masyarakat yang berbeda latar belakang pendidikan. Perbedaan stratifikasi sosial pendidikan pemustaka menimbulkan beragam persepsi tentang fungsi perpustakaan sebagai tempat penyimpanan hasil karya manusia. Penelitian ini bertujuan untuk mengetahui persepsi pemustaka terhadap fungsi penyimpanan di perpustakaan, yakni sebagai tempat penyimpanan buku dan koleksi digital. Metode penelitian kualitatif dengan pendekatan naratif digunakan dalam penelitian ini guna menggali persepsi pemustaka secara lebih mendalam. Hasil penelitian menunjukan perpustakaan dipersepsikan sebagai gudang buku dan gudang pengetahuan. Informan menjelaskan hasil karya manusia yang tersimpan di perpustakaan berupa buku pelajaran, buku cerita, peta, buku fiksi, jurnal, surat kabar, majalah, koleksi referensi, hasil penelitian, bacaan umum dan bacaan untuk anak-anak. Perpustakaan juga dipersepsikan sebagai tempat penyimpanan hasil karya seseorang (buku dan pengetahuan) dalam bentuk digital yang kemudian dilayankan secara online.
Pengembangan Profesionalisme Pustakawan Melalui Pendekatan Etika Moral
Authors: Saefullah Rahmat Setiawan , Haryanto Haryanto
Published: February 2019

Pustakawan merupakan salah satu profesi yang salah satu tugas pokoknya adalah melayani pengunjung atau peminjam koleksi. Bentuk pelayanan terhadap pengguna mengharapkan pustakawan untuk dapat bertugas secara profesional. Tuntutan kerja secara profesional namun apabila tidak diimbangi dengan segenap fasilitas serta hak yang wajib didapatkan, maka akan mengganggu tugas pustakawan itu. Oleh sebab itu, paparan ini akan mencoba mendeskripsikan pengembangan profesionalisme pustakawan melalui etika dan moral yang ada dalam tugas etik profesi pustakawan. Fokus pembahasan dalam tulisan ini adalah bagaimana meningkatkan profesionalisme pustakawan melaui pendekatan etika moral dengan sosialisasi dan internalisasi kode etik pustakawan, serta peningkatan moral atau moralita pustakawasan. Hasil dari paparan ini antara lain, perilaku etis akan dapat meningkatkan pelayanan. Sementara itu, perilaku moral berkontribusi pada pengembangan profesi.
Representasi Profesionalisme Pustakawan dalam Mengelola Perpustakaan pada Film Pendek Project: Library
Authors: Rini Annida Puspa , Laksmi Laksmi
Published: February 2019

Penelitian ini membahas representasi profesionalisme pustakawan dalam mengelola perpustakaan pada film pendek Project: Library. Penelitian ini bertujuan untuk mengidentifikasi representasi profesionalisme pustakawan dalam mengelola perpustakaan dalam film melalui metode semiotic. Hasil penelitian ini menunjukkan bahwa pada analisis sintagmatik, film ini menggunakan alur maju dan profesionalisme pustakawan untuk mengeluarkan perpustakaan dari masalah kebangkrutan dan penggelapan dana terdapat pada 13 sekuen dar 23 sekuen utama. Paradigmatik menunjukkan bahwa profesionalisme pada 3 tokoh pustakawan memiliki nilai keterbukaan dan kerjasama. Kesimpulan menunjukkan bahwa profesionalisme pustakawan direpresentasikan sebagai pustakawan yang lemah dalam memahami fungsi denda, yang bukan dipandang sebagai sarana pendisiplinan pengguna dalam mengembalikan koleksi, tetapi dianggap sebagai sumber pemasukan untuk mencegah kebangkrutan. Namun profesionalisme juga direpresentasikan bahwa dengan menerapkan etika profesi, pustakawan mampu mencegah mereka bersikap negatif, sehingga pada akhirnya  mereka dapat mengungkap kebenaran
Textile Fiber Identification Using Near-Infrared Spectroscopy and Pattern Recognition
Authors: Zhou Jinfeng , Yu Lingjie , Ding Qian , Wang Rongwu
Published: February 2019

Fibers are raw materials used for manufacturing yarns and fabrics, and their properties are closely related to the performances of their derivatives. It is indispensable to implement fiber identification in analyzing textile raw materials. In this paper, seven common fibers, including cotton, tencel, wool, cashmere, polyethylene terephthalate (PET), polylactic acid (PLA), and polypropylene (PP), were prepared. After analyzing the merits and demerits of the current methods used to identify fibers, near-infrared (NIR) spectroscopy was used owing to its significant superiorities, the foremost of which is it can capture the tiny information differences in chemical compositions and morphological features to display the characteristic spectral curve of each fiber. First, the fibers’ spectra were collected, and then, the relationships between the vibrations of characteristic chemical groups and the corresponding wavelengths were researched to organize a spectral information library that would be beneficial to achieve quick identification and classification. Finally, to achieve intelligent detection, pattern recognition approaches, including principal component analysis (PCA) (used to extract information of interest), soft independent modeling of class analogy (SIMCA), and linear discrimination analysis (LDA) (defined using two classifiers), assisted in accomplishing fiber identification. The experimental results – obtained by combining PCA and SIMCA – displayed that five of seven target fibers, namely, cotton, tencel, PP, PLA, and PET, were distributed with 100% recognition rate and 100% rejection rate, but wool and cashmere fibers yielded confusing results and led to relatively low recognition rate because of the high proportion of similarities between these two fibers. Therefore, the six spectral bands of interest unique to wool and cashmere fibers were selected, and the absorbance intensities were imported into the classifier LDA, where wool and cashmere were group-distributed in two different regions with 100% recognition rate. Consequently, the seven target fibers were accurately and quickly distinguished by the NIR method to guide the fiber identification of textile materials.
Synthesis of inorganic polymers under ionizing and super high frequency irradiation: role of reaction media
Authors: Tarasova Natalia P. , Zanin Alexey A.
Published: February 2019

This article provides a general overview of the results of research on the influence of the reaction media and various types of electromagnetic radiation on the polymerization of inorganic monomers, carried out during the last decade at UNESCO Chair in Green Chemistry for Sustainable Development of Dmitry Mendeleev University of Chemical Technology of Russia.
The Distinctiveness Effect in the Recognition of Whole Melodies
Authors: Rainsford Miriam , Palmer Matthew A. , Sauer James D.
Published: February 2019

Distinctive stimuli are better recognized than typical stimuli in many domains (e.g., faces, words). Distinctiveness predicts the point of recognition of a melody (Bailes, 2010), and the recognition of unique tones within a melody (Vuvan, Podolak, & Schmuckler, 2014), yet no studies have examined the role of distinctiveness in recognizing whole melodies. We composed a set of novel melodies according to rules that should result in these being perceived as more or less distinctive. Using computational analysis and human ratings by a group of 36 pilot testers, we established a final stimulus set of 96 novel melodies (48 eightnote, 48 sixteen-note), half of which were high and half low in distinctiveness. A separate group of 26 participants completed a recognition test using this stimulus set. Using linear mixed-effects modeling, we found that greater pitch and interval range, wider intervals, varied contour, and ambiguous tonality within a Western diatonic framework predicted human perception of distinctiveness. However, only a wider modal (most frequent) interval predicted correct recognition. Distinctiveness improved recognition performance in both stimulus lengths; however, a significant advantage was only shown for sixteen-note melodies. Thus, the distinctiveness effect as observed across domains generalizes to the recognition of longer, whole melodies.
Playing Together, Apart
Authors: Iorwerth Miriam , Knox Don
Published: February 2019

Classical musicians in ensembles are accustomed to performing in the same physical space. However, situations such as networked music performance (NMP) require physical separation with audio and sometimes video links. Effects of latency on synchronization have been extensively studied; however, research is limited on the effects of physical separation on the subjective experience of musicians. This separation is likely to have an effect on interaction between musicians as usual channels of communication are interrupted. The impact of this physical separation on the experience of classical musicians in a woodwind soloist and piano accompanist setting was investigated. Three pairs of musicians were recorded in acoustically isolated spaces with audio and video links, and were then interviewed using semi-structured interview techniques. Five themes emerged from the data, namely: adaptability, communication, performance, impact on the musicians, and relationships. Within these themes, musical issues, communication, and social interactions were found to be most challenging for separated musicians, while adaptability helped the musicians in this situation. The video link was used rarely when playing. These issues are important in NMP and are related to the physical separation of the musicians, rather than problems such as latency, which are well documented.
Increased risk of obstructive sleep apnoea in women with polycystic ovary syndrome: a population-based cohort study
Authors: Kumarendran Balachandran , Sumilo Dana , O’Reilly Michael W , Toulis Konstantinos A , Gokhale Krishna M , Wijeyaratne Chandrika N , Coomarasamy Arri , Arlt Wiebke , Tahrani Abd A , Nirantharakumar Krishnarajah
Published: February 2019

Objective

Obesity is very common in patients with obstructive sleep apnoea (OSA) and polycystic ovary syndrome (PCOS). Longitudinal studies assessing OSA risk in PCOS and examining the role of obesity are lacking. Our objective was to assess the risk of OSA in women with vs without PCOS and to examine the role of obesity in the observed findings.

Design

Population-based retrospective cohort study utilizing The Health Improvement Network (THIN), UK.

Methods

76 978 women with PCOS and 143 077 age-, BMI- and location-matched women without PCOS between January 2000 and May 2017 were identified. Hazard ratio (HR) for OSA among women with and without PCOS were calculated after controlling for confounding variables using multivariate Cox models.

Results

Median patient age was 30 (IQR: 25–35) years; median follow-up was 3.5 (IQR: 1.4–7.1) years. We found 298 OSA cases in PCOS women vs 222 in controls, with incidence rates for OSA of 8.1 and 3.3 per 10 000 person years, respectively. Women with PCOS were at increased risk of developing OSA (adjusted HR = 2.26, 95% CI: 1.89–2.69, P < 0.001), with similar HRs for normal weight, overweight and obese PCOS women.

Conclusions

Women with PCOS are at increased risk of developing OSA compared to control women irrespective of obesity. Considering the significant metabolic morbidity associated with OSA, clinicians should have a low threshold to test for OSA in women with PCOS. Whether OSA treatment has an impact on PCOS symptoms and outcomes needs to be examined.
ErbB-2 signaling in advanced prostate cancer progression and potential therapy
Authors: Miller Dannah R , Ingersoll Matthew A , Lin Ming-Fong
Published: February 2019

Currently, prostate cancer (PCa) remains the most commonly diagnosed solid tumor and the second leading cause of cancer-related deaths in US men. Most of these deaths are attributed to the development of castration-resistant (CR) PCa. ErbB-2 and ErbB family members have been demonstrated to contribute to the progression of this lethal disease. In this review, we focus on updating the role of ErbB-2 in advanced PCa progression and its regulation, including its regulation via ligand activation, miRNAs and protein phosphorylation. We also discuss its downstream signaling pathways, including AKT, ERK1/2 and STATs, involved in advanced PCa progression. Additionally, we evaluate the potential of ErbB-2, focusing on its protein hyper-phosphorylation status, as a biomarker for aggressive PCa as well as the effectiveness of ErbB-2 as a target for the treatment of CR PCa via a multitude of approaches, including orally available inhibitors, intratumoral expression of cPAcP, vaccination and immunotherapy.
Defective exocytosis and processing of insulin in a cystic fibrosis mouse model
Authors: Edlund A , Barghouth M , Hühn M , Abels M , Esguerra J S E , Mollet I G , Svedin E , Wendt A , Renström E , Zhang E , Wierup N , Scholte B J , Flodström-Tullberg M , Eliasson L
Published: February 2019

Cystic fibrosis-related diabetes (CFRD) is a common complication for patients with cystic fibrosis (CF), a disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). The cause of CFRD is unclear, but a commonly observed reduction in first-phase insulin secretion suggests defects at the beta cell level. Here we aimed to examine alpha and beta cell function in theCftrtm1EUR/F508del mouse model (C57BL/6J), which carries the most common human mutation inCFTR, the F508del mutation. CFTR expression, beta cell mass, insulin granule distribution, hormone secretion and single cell capacitance changes were evaluated using islets (or beta cells) from F508del mice and age-matched wild type (WT) mice aged 7–10 weeks. Granular pH was measured with DND-189 fluorescence. Serum glucose, insulin and glucagon levels were measuredin vivo, and glucose tolerance was assessed using IPGTT. We show increased secretion of proinsulin and concomitant reduced secretion of C-peptide in islets from F508del mice compared to WT mice. Exocytosis and number of docked granules was reduced. We confirmed reduced granular pH by CFTR stimulation. We detected decreased pancreatic beta cell area, but unchanged beta cell number. Moreover, the F508del mutation caused failure to suppress glucagon secretion leading to hyperglucagonemia. In conclusion, F508del mice have beta cell defects resulting in (1) reduced number of docked insulin granules and reduced exocytosis and (2) potential defective proinsulin cleavage and secretion of immature insulin. These observations provide insight into the functional role of CFTR in pancreatic islets and contribute to increased understanding of the pathogenesis of CFRD.
La posición a asignar a la resocialización en el marco de la teoría de la pena a partir de la declaración contenida en las constituciones de Italia y España
Authors: González Collantes Tàlia
Published: February 2019

En este trabajo me propongo determinar cuál es la posición a asignar a la resocialización en el marco de la teoría de la pena a la luz de lo dispuesto en el artículo 25.2 de la Constitución española. Sin embargo, primero me ocuparé de las diferentes interpretaciones surgidas en Italia en torno al artículo 27.3 de la Constitución de este país, pues creo que el análisis de tal cuestión debe tomar como primer punto de reflexión la comparación entre aquél y éste. Indicaré, asimismo, cómo han resuelto la polémica surgida la Corte Constitucional italiana y nuestro Tribunal Constitucional, los cuales, como intérpretes supremos de la Constitución que son, tienen la última palabra.
Derecho penal y corrupción: acerca de los límites de lo injusto y lo permitido
Authors: Gómez Rivero María del Carmen
Published: February 2019

El trabajo analiza el papel que juegan en el ámbito de los delitos de corrupción algunos principios de elaboración doctrinal orientados a limitar el castigo con base en consideraciones relativas a la tolerancia social de la conducta así como a su insignificancia desde el punto de vista de la entidad de la lesión del bien jurídico. El estudio arroja como resultado un desigual ámbito de aplicación de tales enunciados en el ámbito de la corrupción pública y privada. En relación específica con el delito de cohecho pasivo impropio se ofrecen una serie de pautas en orden a fundamentar espacios de atipicidad de la conducta basadas en la ausencia de lesividad material del interés protegido por la norma penal.
La deriva de los delitos de peligro en la LO 1/2015 de 30 de marzo de reforma del Código penal: la equiparación punitiva de los delitos de peligro dolosos e imprudentes y de los delitos de resultado y peligro abstracto. Una forma de “solventar” la confusa interpretación y aplicación de los tipos penales de peligro.
Authors: Méndez Rodríguez Cristina
Published: February 2019

El trabajo analiza la última reforma del CP por LO 1/2015 de 30 de marzo que continúa con la orientación político criminal que viene marcando en la materia de los delitos de peligro la legislación penal, continúando con la diversificación de las modalidades de peligro (cuya interpretación doctrinal y aplicación jurisprudencial carece por completo del más mínimo acuerdo) y, dando un paso más en en la implementación expansiva de los tipos de peligro al equiparar sancionatoriamente los delitos de peligro dolosos e imprudentes en los artículos 183.4 e), 187.2 c); 188.3 y 189.2 d); y, por otro lado, los delitos de resultado y de peligro abstracto mediante los tipos penales de los artículos 325.1, 326.1 y 326 bis en los que la conducta típica debe “causar o poder causar” daños sustanciales.
Prevaricaciones urbanísticas del art. 320 CP: problemas legislativos no resueltos y dificultades aplicativas, en la práctica reciente
Authors: Gorriz Royo Elena
Published: February 2019

Los delitos de prevaricación urbanística fueron reformados en 2010 si bien, en este trabajo se analiza si las modificaciones introducidas fueron eficaces para perseguir esta clase de corrupción. Para ello se estudia el art. 320 CP en sus dos apartados, estudiando, en particular, las novedosas modalidades omisivas del apartado 1º y, asimismo, los delitos del apartado 2º. En especial, se destacan los problemas que aún sigue planteando aquellos delitos, proponiendo concretas mejoras en su redacción con el fin de orientar su aplicación solo a los casos más graves.
Confisco e gestão do lucro injustificado por corrupção pública em Portugal
Authors: Torrão Fernando
Published: February 2019

Resumo: Considerando as elevadas “cifras negras” normalmente atribuídas aos crimes de corrupção e, bem assim, as dificuldades de deteção do correspondente lucro ilícito, o presente artigo versa sobre alterações legislativas ocorridas em Portugal nos últimos anos, tendo como referência obrigações e recomendações internacionais.
El comiso como estrategia frente a la corrupción en Alemania: interpretación jurisprudencial
Authors: Roig Torres Margarita
Published: February 2019

En Alemania la privación de los bienes del delito se hace a través de dos figuras, el comiso (Verfall) de las ganancias ilícitas, y la confiscación (Einziehung) de los productos y de los objetos empleados en la preparación o ejecución del hecho. Respecto al primero la jurisprudencia afirma que no es una pena o una sanción asimilada a ella, sino una medida para la ordenación del patrimonio y la estabilización de la norma, mientras la segunda es una pena accesoria. En el comiso rige el “principio bruto” (Bruttoprinzip), de modo que se requisa lo obtenido ilícitamente sin descontar los costes de ejecución. El sistema es enteramente distinto al regulado en el Código penal español, donde se asigna al decomiso un carácter civil y patrimonial, basándolo en muchos casos en presunciones legales respecto al origen ilegal de los bienes.
QTL Underlying Circadian Clock Parameters Under Seasonally Variable Field Settings inArabidopsis thaliana
Authors: Rubin Matthew J , Brock Marcus T , Davis Seth J , Weinig Cynthia
Published: February 2019

The circadian clock facilitates coordination of the internal rhythms of an organism to daily environmental conditions, such as the light-dark cycle of one day. Circadian period length (the duration of one endogenous cycle) and phase (the timing of peak activity) exhibit quantitative variation in natural populations. Here, we measured circadian period and phase in June, July and September in three Arabidopsis thaliana recombinant inbred line populations. Circadian period and phase were estimated from bioluminescence of a genetic construct between a native circadian clock gene (COLD CIRCADIAN RHYTHM RNA BINDING 2) and the reporter gene (LUCIFERASE) after lines were entrained under field settings. Using a Bayesian mapping approach, we estimated the median number and effect size of genomic regions (Quantitative Trait Loci, QTL) underlying circadian parameters and the degree to which these regions overlap across months of the growing season. We also tested for QTL associations between the circadian clock and plant morphology. The genetic architecture of circadian phase was largely independent across months, as evidenced by the fact that QTL determining phase values in one month of the growing season were different from those determining phase in a second month. QTL for circadian parameters were shared with both cauline and rosette branching in at least one mapping population. The results provide insights into the QTL architecture of the clock under field settings, and suggest that the circadian clock is highly responsive to changing environments and that selection can act on clock phase in a nuanced manner.
The Effects of Chavez's Populism on Today's Venezuela
Authors: Messina Italia
Published: February 2019

This research analyzes the current economic crisis in Venezuela and its impact on human rights. The majority of Venezuelan citizens have been negatively impacted by hyperinflation, deteriorating healthcare systems, and government corruption. Mass emigration of Venezuelans to neighboring countries has placed great stress on the region as a whole, and the international community has yet to recognize Venezuela’s plight as an official refugee crisis. Drawing upon recent news articles, this research intends to understand how the economic system left in place by former Venezuelan president Hugo Chavez began to crumble after current Venezuelan president Nicolas Maduro was elected. It utilizes diverse news sources to analyze the causes of Venezuela’s sunken economy in order to provide insight towards plausible solutions. Exploring various options for alleviating economic hardship at the individual and nation-state levels, this paper aims to reflect on ways in which government corruption and consolidation of power within the Venezuelan political system could be eradicated. I have briefly analyzed the efficacy of methods such as economic sanctions, external military intervention, humanitarian aid, and collective action in alleviating Venezuela’s problems. As evidenced by this research, there is not one concrete, unambiguous answer to the problem at hand. Implications remain in each of the aforementioned methods of alleviating suffering in Venezuela. Stronger economic sanctions will further worsen Venezuela before it betters it, external military intervention will solidify fears of imperialism, and collective action by the international community has proven to be disorganized. This paper draws parallels to many of the sources cited within it, in that humanitarian aid is of dire need until long-term actions are taken to reform Venezuela’s economy.
Die „gespaltene Auslegung“ von Verhaltensnormen im Straf-, Aufsichts- und Zivilrecht oder wer gibt den Ton an?
Authors: Poelzig Dörte
Published: February 2019

In zwei aktuellen Entscheidungen jeweils vom 25. 9. 2018 haben der BGH zum Acting in Concert gem. § 34 Abs. 2 WpHG und das KG zur Erlaubnispflicht für den Handel mit Bitcoin gem. § 32 KWG der Auffassung der BaFin, die sie im Emittentenleitfaden bzw. in einem Merkblatt verlautbart hat, ausdrücklich widersprochen. Die Entscheidungen werfen damit die Frage auf, ob und inwieweit bankaufsichts- und kapitalmarktrechtliche Normen, die durch ein Nebeneinander von Straf- bzw. Bußgeld-, Aufsichts- und Zivilrecht durchgesetzt werden, unterschiedlich ausgelegt werden können. Quelle für eine solche gespaltene Auslegung ist vor allem der strafrechtliche Bestimmtheitsgrundsatz, der im Straf- und Bußgeldrecht, aber grundsätzlich nicht im Zivil- und Aufsichtsrecht gilt. Außerdem stellt sich die Frage, ob und inwieweit die Verlautbarungen der BaFin zu ihrer Rechtsauffassung rechtsgestaltende Wirkung entfalten und eine gespaltene Auslegung verhindern können.
Reichweite der Frühinterventionsbefugnisse der Aufsichtsbehörden nach § 36 Abs. 1 Satz 3 Nr. 1 lit. e SAG
Authors: Struckman Jan
Published: February 2019

Der Beitrag beschäftigt sich mit der Reichweite der Frühinterventionsbefugnisse der Bankaufsichtsbehörden am Beispiel von § 36 Abs. 1 Satz 3 Nr. 1 lit. e SAG, der es BaFin und EZB gestattet, Eingriffe in die Geschäftsstrategie sowie die rechtlichen und operativen Strukturen eines Instituts vorzunehmen. Es wird gezeigt, dass der deutsche Gesetzgeber nicht in allen Bereichen die BRRD konsequent umgesetzt hat, was eine richtlinienkonforme Auslegung von § 36 SAG notwendig macht. Überdies sprechen die Systematik der Norm, die Erwägungsgründe und die Entstehungsgeschichte der BRRD für eine einschränkende Auslegung der Aufsichtsbefugnisse im Bereich der „Geschäftsstrategie sowie der rechtlichen und operativen Strukturen des Instituts“, die die Rechte der Aktionäre umfassend berücksichtigt und damit ausnahmsweise dem Gesellschaftsrecht Vorrang vor dem Aufsichtsrecht einräumt.
Optimizing Drug-Drug Interaction Alerts Using a Multidimensional Approach
Authors: Daniels Calvin C. , Burlison Jonathan D. , Baker Donald K. , Robertson Jennifer , Sablauer Andras , Flynn Patricia M. , Campbell Patrick K. , Hoffman James M.
Published: February 2019

OBJECTIVES:

Excessive alerts are a common concern associated with clinical decision support systems that monitor drug-drug interactions (DDIs). To reduce the number of low-value interruptive DDI alerts at our hospital, we implemented an iterative, multidimensional quality improvement effort, which included an interdisciplinary advisory group, alert metrics, and measurement of perceived clinical value.

METHODS:

Alert data analysis indicated that DDIs were the most common interruptive medication alert. An interdisciplinary alert advisory group was formed to provide expert advice and oversight for alert refinement and ongoing review of alert data. Alert data were categorized into drug classes and analyzed to identify DDI alerts for refinement. Refinement strategies included alert suppression and modification of alerts to be contextually aware.

RESULTS:

On the basis of historical analysis of classified DDI alerts, 26 alert refinements were implemented, representing 47% of all alerts. Alert refinement efforts resulted in the following substantial decreases in the number of interruptive DDI alerts: 40% for all clinicians (22.9–14 per 100 orders) and as high as 82% for attending physicians (6.5–1.2 per 100 orders). Two patient safety events related to alert refinements were reported during the project period.

CONCLUSIONS:

Our quality improvement effort refined 47% of all DDI alerts that were firing during historical analysis, significantly reduced the number of DDI alerts in a 54-week period, and established a model for sustained alert refinements.
First records of the occurrence of twelve species of Sabethini (Diptera, Culicidae) in the state of Paraná, southern Brazil
Authors: Silva Allan Martins da , Santos Demilson Rodrigues dos , Cristóvão Edilson Colhera , Ferreira Adão Celestino , Postai Claudomiro , Westphal-Ferreira Betina , Silva Mário Antônio Navarro da
Published: February 2019

We report on the first records of Sabethini mosquitoes in the state of Paraná, based on specimens collected in forested environments between 2004 and 2005. In total, 12 species were identified, including 7 species of Wyeomyia Theobald, 1901 and 5 species of Sabethes Robineau-Desvoidy, 1827. Among them, 6 are new records for the southern region of the country, and 6 are new records for the state of Paraná. These results indicate the occurrence of relict species of mosquitoes in Paraná, as they were collected from portions of forests that preserve original characteristics.​​​
Survey of medium-sized and large mammals in semideciduous Atlantic Forest patches near Alfenas, southern Minas Gerais, Brazil
Authors: Costa Ana Raíssa Cunha , Passamani Marcelo , da Cunha Rogério Grassetto Teixeira
Published: February 2019

We surveyed, with the aid of camera traps, medium-sized and large terrestrial mammals in 8 patches of semideciduous Atlantic Forest near the city of Alfenas, Minas Gerais, Brazil. We recorded species occurrence using 2 camera traps per fragment, which were simultaneously active for 2 months each. We recorded 16 species, plus a species of armadillo that we were unable to identify to genus. The rarefaction curve tended to stabilize, evidencing the efficacy of our methods. The species richness was similar or higher to other surveys carried out in remnants of seasonal semideciduous Atlantic Forest or transitional areas. However, such seemingly high richness in a severely degraded and fragmented region, including large carnivores and endangered species, hides a wide variation in richness among fragments. This calls for urgent actions to improve the landscape for these animals to ensure their survival in the long term, as some populations are probably not viable in the long run.
Virtual microscopy enhances the reliability and validity in histopathology curriculum: Practical guidelines
Authors: Nauhria Samal , Hangfu Lee
Published: February 2019

This article was migrated. The article was not marked as recommended. Digital pathology innovation and application in medical education have paved the path for a significant shift in the advancement of the medical curriculum. The new technology of virtual microscopy is a proven reliable and valid pedagogy method for histopathology learning objectives, and assessments. The current transformation has brought educators around the globe nearer towards the goal of achieving competence in Curriculum Inventory in the medical curriculum. This paper emphasises the practical tips and guidelines for cost-effective implementation and the successful use of Virtual Microscope technology to enhance the histopathology curriculum in a medical school.
Comparative Study of Inhibitory Potential of Dietary Phytochemicals Against Quorum Sensing Activity of and Biofilm Formation by Chromobacterium violaceum 12472, and Swimming and Swarming Behaviour of Pseudomonas aeruginosa PAO1
Authors: Bali Elif Burcu , Erkan Türkmen Kübra , Erdönmez Demet , Sağlam Necdet
Published: February 2019

Quorum sensing (QS) and biofilm formation are important mechanisms related to antibiotic resistance of many pathogens. Alternative treatments are needed to prevent recurrent or chronic infections caused by multi-resistant pathogens. Therefore, the aim of this study is to investigate and compare the inhibitory potential of the dietary phytochemicals: curcumin, quercetin, apigenin, pyrogallol, gallic acid and luteolin against QS of and biofilm formation by Chromobacterium violaceum ATCC 12472 and the swimming and swarming abilities of Pseudomonas aeruginosa PAO1. Anti-QS potential of the phytochemicals was evaluated qualitatively and quantitatively using C. violaceum via the disk diffusion assay based on violacein pigment inhibition at the subminimal inhibitory concentrations ranging from 46.87 to 750 µg/mL. The results of anti-QS and antibiofilm activities on C. violaceum demonstrated that all the phytochemicals except pyrogallol and gallic acid inhibited violacein production (from (11.0±0.1) to (88.2±0.1) %) in a concentration-dependent manner. In addition, the biofilm formation was also significantly inhibited (p<0.05) in the presence of all the phytochemicals ((1.38±0.08)–(84.2±0.2) %). In the present study, the results revealed that quercetin, curcumin, apigenin and luteolin could be promising QS and biofilm inhibitory agents against the C. violaceum 12472 biosensor system. Our findings also suggest that all the phytochemicals, especially curcumin, quercetin and pyrogallol, might be anti-pathogenic agents against P. aeruginosa PAO1 infections due to the ability to control QS. However, more comprehensive studies at the molecular level, explaining their anti-QS mechanisms, need to be conducted to confirm these results and identify the genes involved.
The relationship between project performance of emerging contractors in government infrastructure projects and their experience and technical qualifications
Authors: Muzondo F , McCutcheon R
Published: February 2019

Various studies have been conducted to investigate the reasons for the comparative failure of small contractors. Many of these studies have found the reasons for failure to be primarily related to factors that are beyond the control of the contractor or business management. Little attention has been paid to technical factors. This study sought to investigate the correlation between the performance of emerging contractors in government infrastructure projects to their technical qualifications and experience. An archive research methodology was adopted where contractor performance information was collected on 30 CE and GB projects conducted in Mpumalanga Province. The project data was then used alongside contractor qualification and experience data to investigate their relationship. When evaluating the qualification level, it was found that contractors with higher qualifications show better performance. It was also found that contractors with more technical qualifications perform better than those without. This study also concluded that contractors with more years of experience in the construction industry show better project performance. It is recommended that a much broader investigation must be carried out to examine to what extent these conclusions are applicable throughout South Africa. If so, there are important implications for the modification of existing procurement policy and procurement practice.
Catchment response time and design rainfall: the key input parameters for design flood estimation in ungauged catchments
Authors: Gericke O
Published: February 2019

Catchment response time and design rainfall are regarded as fundamental input to all design flood estimation methods in ungauged catchments, while errors in estimated catchment response time and design rainfall directly impact on estimated peak discharges. This paper presents the independent testing and comparison of the latest catchment response time and design rainfall estimation methodologies with current well-known and simplified methodologies used in South Africa to ultimately highlight the impact thereof on design flood estimation. The results confirmed that catchment response time, design rainfall, and to some lesser extent runoff coefficients, are the key input parameters for design flood estimation in ungauged catchments and have a significant impact on the design of hydraulic structures. It is recommended that the current well-known and simplified catchment response time (USBR TCequation) and design rainfall (modified Hershfield/TR102 DDF approach) estimation methodologies should be replaced with the empirical G&S TCequations and the RLMA&SI DDF approach when deterministic design floods are estimated in ungauged catchments in South Africa.
High quality DNA from Fungi for next generation sequencing e.g. Illumina, PacBio, Nanopore MinION v1
Authors: Bar Ido
Published: February 2019

Extraction of high quality DNA for long read sequencing e.g. PacBio and MinIon Optimized for DNA extraction fromBipolaris sorokiniana. Also tested on Ascochyta rabiei, Parastaognospora nodorum, Zymoseptoria tritici, wheat stripe rust, barley stripe rust and Pyrenophora tritici-repentis Buffers are best when fresh and not older than 3-6 months. Buffered Phenol:Chloroform:Isoamylalcohol (25:24:1) should not be older than 3 months. Critical steps to obtain high quality DNA: Do NOT heat samples during DNA extractions! Perform all steps at RT or 4°C as indicated. Do NOT incubate samples with KAc for prolonged time periods Perform two steps of buffered Phenol:Chloroform:Isoamylalcohol purification to reduce co-purifying metabolites. DNA fragments were well above the 40kb mark based on Pippin Pulse Gels. The sequencing center performed a second AMPure purification step before library construction.
An Analysis of Nautical and Cruise Tourism in Slovenia (2005-2015) and its Position among other Mediterranean countries
Authors: Uran Maravić Maja , Martinič Nataša , Barkiđija Sotošek Marina
Published: February 2019

This article is dedicated to presenting nautical tourism in Slovenia. The basic purpose is to evaluate the extent of nautical tourism, since data on this type of tourism in Slovenia are lacking. Slovenia has three marinas, a few moorings and a passenger terminal. Despite its small coastal strip (46 km), all forms of nautical tourism are represented. This article consists of theoretical and analytical work. The theoretical part presents a number of basic definitions relating to nautical tourism and cruises. This work will also present the development of this form of tourism in Slovenia to date. Slovenia’s first marina was built in 1979 in Portorož, while cruise tourism in Slovenia began later, in 2005. Due to its diversity in a small area, Slovenia is an ideal starting point for (maritime) excursions. In the analytical part, numerical traffic data for the period 2005 to 2015 from marinas and the Port of Koper have been collated and analysed. This work is based on data collected by the marinas themselves, since the official nautical traffic statistics are not recorded. The main results of our analysis indicate that nautical tourism in Slovenia has experienced a large decline since 2005. The exception is cruise tourism, which has shown strong growth.
Facilitating Seafarers Employment Using a Common Database
Authors: Pijevac Maria , Tijan Edvard , Jardas Mladen
Published: February 2019

A key part of the maritime crewing agent business is the employment of seafarers (apart from drafting contracts between ship owners and seafarers), finding suitable personnel to fill the job vacancies advertised by ship owners. Maritime crewing agencies generally keep records of seafarers in their own databases. However, those databases often happen to fall short of the requested professionals (officers) and/or the support staff. In such cases, agencies spend a lot of time on finding the personnel possessed of the required qualifications and experience. This paper researches the positive and negative sides of a common database of seafarers, their meaningfulness or drawbacks, and the attitudes of maritime crewing agencies relating to common databases. A survey was conducted among Croatian maritime crewing agencies in order to obtain information on their operations and opinions concerning the proposed common seafarer database.
Selection of suitable locations for nautical tourism ports in the Ličko-senjska County
Authors: Badurina Tomić Paola , Dundović Čedomir , Grubišić Neven
Published: February 2019

Nautical tourism has become an increasingly popular way of respite, and for a country possessed of nautical capacities it represents a very important factor in the development of tourism in general. Strategy for the development of nautical tourism for the period 2009-2019 has predicted a special nautical capacity growth for the Ličko-senjska County, which is not particularly abundant in nautical capacities. In accordance with the respective spatial plans, also containing decisions adopted in respect of future development of nautical tourism, there were five proposed locations taken in account in this paper for the selection of a suitable location in the Ličko-senjska County. Using the multi-criteria analysis and the VISUAL PROMETHEE software program, location 1-Novalja was selected as the most suitable one. The contribution of this work is primarily reflected upon the analysis of previous research works and the adoption of possible measures for further development of nautical tourism in the Ličko-senjska County.
Effect of smoking on vitamin C and MDA: a cross sectional comparative study
Authors: Kubihal Chandrashekar V. , Naik Hemalatha D.
Published: February 2019

Background: Plasma gets exposed to the gases present in the smoke of the cigarette which leads to peroxidation. The ascorbic acid present in the body gets oxidized there is danger of derangement of lipid profile. The measure of malondialdehyde which is formed in lipid peroxidation reaction is indicative of oxidative stress. Oxidative stress seen among the smokers has been attributed to high MDA levels. Objective was to study the effect of smoking on vitamin C and MDA.Methods: Present study was cross sectional study. Two groups of subjects were compared. Out of 100 study subjects, 25 were non smokers and were kept in one group. Remaining 75 were smokers. These two groups were compared to find out how the smoking habit affects the MDA as well as vitamin C levels among them.Results: The levels of MDA were more in smokers compared to those who did not smoke and this difference was significant. The levels of vitamin C were less in smokers compared to those who did not smoke and this difference was significant (p<0.05). It was found that the MDA levels were significantly more among all degrees of smokers. It was less in smokers with mild degree compared to smokers with heavy or moderate degree. Level of vitamin C was more in non smokers compared to smokers. Mild degree of smokers had better levels of vitamin C compared to moderate degree of smokers.Conclusions: Smoking affects the vitamin C levels and MDA levels in the human body.
A prospective observational study to analyse clinical profile of varicose vein cases treated in a tertiary care hospital
Authors: Mani Maragadha , A. Anand
Published: February 2019

Background: Varicose veins are common vascular disorder. The study was conducted to analyse the clinical presentation, treatment options and complications of varicose veins.Methods: This observational study was conducted in Thanjavur Medical College Hospital. Adults with clinically diagnosed unilateral or bilateral varicose veins of lower limbs were studied in surgical wards between August 2013 to July 2014. The demographic data and presenting symptoms, signs and previous treatment were collected using a structured proforma. Thorough clinical examination, duplex scan and abdominal and pelvic examination were done in all cases to find out the secondary causes. Peripheral vascular system was examined. All the patients were followed regularly for the period of one month to one year after treatment.Results: A total of 60 cases were included. Most participants belonged to 2nd and 3rd decade of life. 55 (91%) participants were male and5 (9%) participants were females. 45 (75%) participants were agriculturists. 10 (17%) participants had bilateral involvement. Most participants 30 (50%) participants had 1 to 5 years duration of disease, most common clinical presentation of the study participants was varicosity with 70.0%, followed by lipodermo sclerosis, leg pain, hyperpigmentation, pruritus as 63.0%, 56.0%, 15% and 11.6% respectively. 17 (28.33%) patients were present with a venous ulcer. 32 (53%) participants were managed surgically, and 28 (47%) participants were managed conservatively. Most participants were treated with multiple ligation 21.8% followed by trendelenburg operation+ stripping18.75%.Conclusions: Regarding the treatment, surgery is the treatment of choice for primary varicose veins and conservative treatment for secondary varicose veins.
POLA KOMUNIKASI KELUARGA DALAM PEMBENTUKAN KEPRIBADIAN ANAK
Authors: Rahmah Siti
Published: February 2019

Humans are social creatures who need a good relationship with other people, and have the urge to relate to other people and other impulses such as curiosity, self-actualization, and so on, it will be discarded by communicating with each other. Because humans can always develop and be able to carry out community life, of course, with communication, which can be done at any time, when, by whom and with anyone. Likewise with communication for a child in a family who has work to be used in the community. Parents in a family become a figure for children in the form of the same thing, behavior, speech words formed by parents of parents. The key pattern of communication in the family that is built will affect the parenting style of the children. With good communication patterns will create good parenting patterns, the formation of children in the family form as an effort of parents for the virtue of behaving that must be done early is the basis of education. The formation of awareness as the basis of education is a manifestation of the formation of a child's personality.
SIARAN DENGAN CONTENT POSITIF DAN EDUKATIF
Authors: Surianor Surianor
Published: February 2019

This journal addresses the topic of radio and television broadcasts which are mostly filled with dangdut songs and other events which are sometimes not in accordance with religious norms and regulations in the broadcasting sector. This is indicated by the presence of a number of songs that were hit by reprimand, both by the MUI, the KPID and from the sworddut itself. The problem here is what songs have been broadcast by radio / television and then reprimanded by the authorities, and what songs should be the contents of radio or television broadcasts that are positively charged and educative. This journal is indeed a number of songs that have been banned from being broadcast by radio or television, both because of the lyrics / poetry and the erotic movements of the singers which are categorized as containing pornography and porno-action. Songs should be created and broadcast in line with religious values, customs and regulations, without losing their artistic value, including regional songs. Such songs will be eternal, even though the creator or singer is gone