bluuebunny/crossref_metadata_2025 huggingface dataset:
Acknowledgments in scientific publications: Presence in Spanish science and text patterns across disciplines
Authors: Díaz‐Faes Adrián A. , Bordons María
Published: April 2014

The acknowledgments in scientific publications are an important feature in the scholarly communication process. This research analyzes funding acknowledgment presence in scientific publications and introduces a novel approach for discovering text patterns by discipline in the acknowledgment section of papers. First, the presence of acknowledgments in 38,257 English‐language papers published by Spanish researchers in 2010 is studied by subject area on the basis of the funding acknowledgment information available in the Web of Science database. Funding acknowledgments are present in two thirds of Spanish articles, with significant differences by subject area, number of authors, impact factor of journals, and, in one specific area, basic/applied nature of research. Second, the existence of specific acknowledgment patterns in English‐language papers of Spanish researchers in 4 selected subject categories (cardiac and cardiovascular systems, economics, evolutionary biology, and statistics and probability) is explored through a combination of text mining and multivariate analyses. “Peer interactive communication” predominates in the more theoretical or social‐oriented fields (statistics and probability, economics), whereas the recognition of technical assistance is more common in experimental research (evolutionary biology), and the mention of potential conflicts of interest emerges forcefully in the clinical field (cardiac and cardiovascular systems). The systematic inclusion of structured data about acknowledgments in journal articles and bibliographic databases would have a positive impact on the study of collaboration practices in science.
Linking information through function
Authors: Zhang Lei
Published: April 2014

How information resources can be meaningfully related has been addressed in contexts from bibliographic entries to hyperlinks and, more recently, linked data. The genre structure and relationships among genre structure constituents shed new light on organizing information by purpose or function. This study examines the relationships among a set of functional units previously constructed in a taxonomy, each of which is a chunk of information embedded in a document and is distinct in terms of its communicative function. Through a card‐sort study, relationships among functional units were identified with regard to their occurrence and function. The findings suggest that a group of functional units can be identified, collocated, and navigated by particular relationships. Understanding how functional units are related to each other is significant in linking information pieces in documents to support finding, aggregating, and navigating information in a distributed information environment.
Open‐access repositories worldwide, 2005–2012: Past growth, current characteristics, and future possibilities
Authors: Pinfield Stephen , Salter Jennifer , Bath Peter A. , Hubbard Bill , Millington Peter , Anders Jane H.S. , Hussain Azhar
Published: April 2014

This paper reviews the worldwide growth of open‐access (OA) repositories, 2005 to 2012, using data collected by the OpenDOAR project. Initial repository development was focused on North America, Western Europe, and Australasia, particularly the United States, United Kingdom, Germany, and Australia, followed by Japan. Since 2010, there has been repository growth in East Asia, South America, and Eastern Europe, especially in Taiwan, Brazil, and Poland. During the period, some countries, including France, Italy, and Spain, have maintained steady growth, whereas other countries, notably China and Russia, have experienced limited growth. Globally, repositories are predominantly institutional, multidisciplinary and English‐language based. They typically use open‐source OAI‐compliant software but have immature licensing arrangements. Although the size of repositories is difficult to assess accurately, available data indicate that a small number of large repositories and a large number of small repositories make up the repository landscape. These trends are analyzed using innovation diffusion theory, which is shown to provide a useful explanatory framework for repository adoption at global, national, organizational, and individual levels. Major factors affecting both the initial development of repositories and their take‐up include IT infrastructure, cultural factors, policy initiatives, awareness‐raising activity, and usage mandates. Mandates are likely to be crucial in determining future repository development.
Withdrawal: ‘A new type of misconduct in the field of the physical sciences: The case of the pseudonyms used by I. Ciufolini to anonymously criticize other people's works on arXiv’ by L. Iorio
Authors: Iorio L.
Published: April 2014

The above article, published online on 28 April 2014 in Wiley Online Library (wileyonlinelibrary.com), has been withdrawn with agreement from the journal Editor‐in‐Chief, Blaise Cronin, and Wiley Periodicals, Inc. The withdrawal has been agreed for legal reasons.
Testing the Extreme Male Brain Theory of Autism Spectrum Disorder in a Familial Design
Authors: Hauth Ingeborg , de Bruijn Yvette G. E. , Staal Wouter , Buitelaar Jan K. , Rommelse Nanda N.
Published: April 2014

Autism Spectrum Disorder (ASD) may be an extreme manifestation of some male‐typical traits in both neuroanatomy and cognition. Using the ratio of the second to fourth digit (2D:4D) and digit length as biomarkers of (pre‐ and postnatal) testosterone levels, examined was whether hypermasculinized digit ratios and/or lengths were familial traits in ASD and investigated their relation to sexually dimorphic cognitive abilities. 2D:4D ratios and digit lengths of 216 children with ASD, 202 unaffected siblings, and 360 parents were compared with those of 174 control children and their 146 parents. Generalized Estimation Equations, Generalized Linear Models, and Linear Mixed Models were used to investigate parent–offspring relationships and group differences. In ASD probands and their relatives alike, digit length relative to overall height was significantly increased in comparison to controls. No significant group differences were found between affected and unaffected subjects, or between males and females. Additionally, 2D:4D ratios increased with age. No (consistent) associations were found between 2D:4D ratio or digit lengths and systemizing and empathizing skills. The findings emphasize the role of familially based elevated pre‐ and postnatal testosterone levels in the liability for ASD, but challenge the use of 2D:4D ratio as a proxy of prenatal testosterone exposure solely. Given that many genes influence digit length, the exact mechanisms underlying a familial predisposition toward increased digit length in ASD are as yet unknown and needs to be explored in future studies. Autism Res 2014, 7: 491–500. © 2014 International Society for Autism Research, Wiley Periodicals, Inc.
A simple, rapid one‐step ELISA using antibody–antibody complex
Authors: Jiang Wenwen , Liu Xiaoli , Wu Di , Wang Hongwei , Wang Yanwei , Chen Hong , Yuan Lin
Published: April 2014

The enzyme‐linked immunosorbent assay (ELISA) is one of the most frequently employed assays for clinical diagnostic testing and biological research. However, its time‐consuming operation is a major drawback. The present work aims to establish a one‐step ELISA method through the preparation of a primary antibody (Ab)–secondary Ab complex (Ab–Ab complex) in hopes of realizing more sensitive and faster detection of the trace amount of antigen (Ag). By controlling the mole ratio of the primary Ab to the secondary Ab, one‐step ELISA can be successfully achieved. Compared with the traditional ELISA, the one‐step ELISA could not only improve the detection sensitivity to 1 ng mL−1, but also reduce the operating time by 30%. Moreover, the signal intensity can be controlled by adjusting the ratio of the secondary Ab in the complex or by changing the color development time. This technique is further optimized to detect trace amounts of proteins adsorbed onto poly(N‐vinylpyrrolidone) (PVP)‐modified silicon surfaces (Si‐PVP), and the results are close to the radiolabeling method. It is concluded that the simple one‐step ELISA can be used for the rapid detection of trace amount of protein. The method holds promise for the clinical detection of trace Ag in solution and on low‐adsorption material surfaces.
Synthesis and spectral investigations of Cu(II) ion‐doped NaCaAlPO4F3 phosphor
Authors: Manjari V. Pushpa , Krishna Ch. Rama , Reddy Ch. Venkata , Ravikumar R. V. S. S. N.
Published: April 2014

Cu(II) ion‐doped NaCaAlPO4F3 phosphor has been synthesized using a solid state reaction method. The prepared sample is characterized by powder X‐ray diffraction, scanning electron microscope, optical absorption, electron paramagnetic resonance photoluminescence and Fourier transform infrared spectroscopy techniques. The crystallite size evaluated from x‐ray diffraction data is in nanometers. Scanning electron microscopy micrographs showed the presence of several irregular shaped particles. From optical absorption and electron paramagnetic resonance spectral data the doped Cu(II) ions are ascribed to distorted octahedral site symmetry. The synthesized phosphor exhibits emission bands in ultraviolet, blue and green regions under the excitation wavelength of 335 nm. The CIE chromaticity coordinates (x = 0.159, y = 0.204) also calculated for the prepared sample from the emission spectrum. The Fourier transform infrared spectroscopy spectrum revealed the characteristic vibrational bands of the prepared phosphor material. Copyright © 2014 John Wiley & Sons, Ltd.
Estimated risk of cancer transmission from organ donor to graft recipient in a national transplantation registry
Authors: Desai R , Collett D , Watson C J E , Johnson P , Evans T , Neuberger J
Published: April 2014

Background

Transplanted organs carry the risk of inadvertent donor cancer transmission. Some cancers in organ donors have been classified as being associated with a high or unacceptable risk, but the evidence for such recommendations is scanty.

Methods

The risk of cancer transmission from donors characterized as high or unacceptable risk was studied by analysing transplant and cancer registry data. Donors and recipients from England (1990–2008) were identified from the UK Transplant Registry. Cancer details were obtained from cancer registries and classified using guidelines from the Council of Europe and Organ Procurement and Transplantation Network/United Network for Organ Sharing.

Results

Of 17 639 donors, 202 (1·1 per cent) had a history of cancer, including 61 donors with cancers classed as having an unacceptable/high risk of transmission. No cancer transmission was noted in 133 recipients of organs from these 61 donors. At 10 years after transplantation, the additional survival benefit gained by transplanting organs from donors with unacceptable/high-risk cancer was 944 (95 per cent confidence interval (c.i.) 851 to 1037) life-years, with a mean survival of 7·1 (95 per cent c.i. 6·4 to 7·8) years per recipient.

Conclusion

Strict implementation of present guidelines is likely to result in overestimation of cancer transmission risk in some donors. Organs from some donors with cancers defined as unacceptable/high risk can be used safely.
Donor age as a risk factor in donation after circulatory death liver transplantation in a controlled withdrawal protocol programme
Authors: Detry O , Deroover A , Meurisse N , Hans M F , Delwaide J , Lauwick S , Kaba A , Joris J , Meurisse M , Honoré P
Published: April 2014

Background

Results of donation after circulatory death (DCD) liver transplantation are impaired by graft loss, resulting mainly from non-anastomotic biliary stricture. Donor age is a risk factor in deceased donor liver transplantation, and particularly in DCD liver transplantation. At the authors' institute, age is not an absolute exclusion criterion for discarding DCD liver grafts, DCD donors receive comfort therapy before withdrawal, and cold ischaemia is minimized.

Methods

All consecutive DCD liver transplantations performed from 2003 to 2012 were studied retrospectively. Three age groups were compared in terms of donor and recipient demographics, procurement and transplantation conditions, peak laboratory values during the first post-transplant 72 h, and results at 1 and 3 years.

Results

A total of 70 DCD liver transplants were performed, including 32 liver grafts from donors aged 55 years or less, 20 aged 56–69 years, and 18 aged 70 years or more. The overall graft survival rate at 1 month, 1 and 3 years was 99, 91 and 72 per cent respectively, with no graft lost secondary to non-anastomotic stricture. No difference other than age was noted between the three groups for donor or recipient characteristics, or procurement conditions. No primary non-function occurred, but one patient needed retransplantation for artery thrombosis. Biliary complications were similar in the three groups. Graft and patient survival rates were no different at 1 and 3 years between the three groups (P = 0·605).

Conclusion

Results for DCD liver transplantation from younger and older donors were similar. Donor age above 50 years should not be a contraindication to DCD liver transplantation if other donor risk factors (such as warm and cold ischaemia time) are minimized.
Validation of LC‐MS/MS method applied to evaluation of free tissue concentrations of vildagliptin in diabetic rats by microdialysis
Authors: de Andrade Cristiane , de Araújo Lock Graziela , Pigatto Maiara Cássia , Haas Sandra Elisa , Costa Teresa Dalla , de Araújo Bibiana Verlindo
Published: April 2014

A novel LC‐MS/MS method was developed for the quantification of vildagliptin in an aqueous matrix. The method was successfully validated, meeting all the requisites of US Food and Drug Administration guide for a bioanalytical method. The developed method presented a limit of quantification of 10 ng/mL and the range of concentration achieved was 10–1875 ng/mL. The injection volume necessary was only 10 μL, and retention time was 4.60 min. The mobile phase employed was methanol–ammonium acetate 5 mm (95:5). The stability of the drug was evaluated in the different conditions through which the samples passed. A pharmacokinetic experiment was conducted with diabetic male Wistar rats, and the concentration of drug in liver was evaluated through a microdialysis technique. The perfusion fluid employed was ultrapure water. The dose administrated was 50 mg/kg and the method allowed the quantification of vildagliptin for more than three half lives, successfully characterizing the pharmacokinetic profile when the developed method was applied. This is the first report on the tissue pharmacokinetics of a DPP‐4 inhibitor and could contribute to drug dosage optimization in the future. Copyright © 2014 John Wiley & Sons, Ltd.
Over‐pressurized bioreactors: Application to microbial cell cultures
Authors: Lopes Marlene , Belo Isabel , Mota Manuel
Published: April 2014

In industrial biotechnology, microbial cultures are exposed to different local pressures inside bioreactors. Depending on the microbial species and strains, the increased pressure may have detrimental or beneficial effects on cellular growth and product formation. In this review, the effects of increased air pressure on various microbial cultures growing in bioreactors under moderate total pressure conditions (maximum, 15 bar) will be discussed. Recent data illustrating the diversity of increased air pressure effects at different levels in microbial cells cultivation will be presented, with particular attention to the effects of oxygen and carbon dioxide partial pressures on cellular growth and product formation, and the concomitant effect of oxygen pressure on antioxidant cellular defense mechanisms. © 2014 American Institute of Chemical Engineers Biotechnol. Prog., 30:767–775, 2014
Guidance for performing multivariate data analysis of bioprocessing data: Pitfalls and recommendations
Authors: Rathore Anurag S. , Mittal Shachi , Pathak Mili , Arora Arushi
Published: April 2014

Biotech unit operations are often characterized by a large number of inputs (operational parameters) and outputs (performance parameters) along with complex correlations among them. A typical biotech process starts with the vial of the cell bank, ends with the final product, and has anywhere from 15 to 30 such unit operations in series. Besides the above‐mentioned operational parameters, raw material attributes can also impact process performance and product quality as well as interact among each other. Multivariate data analysis (MVDA) offers an effective approach to gather process understanding from such complex datasets. Review of literature suggests that the use of MVDA is rapidly increasing, fuelled by the gradual acceptance of quality by design (QbD) and process analytical technology (PAT) among the regulators and the biotech industry. Implementation of QbD and PAT requires enhanced process and product understanding. In this article, we first discuss the most critical issues that a practitioner needs to be aware of while performing MVDA of bioprocessing data. Next, we present a step by step procedure for performing such analysis. Industrial case studies are used to elucidate the various underlying concepts. With the increasing usage of MVDA, we hope that this article would be a useful resource for present and future practitioners of MVDA. © 2014 American Institute of Chemical Engineers Biotechnol. Prog., 30:967–973, 2014
Charge Density Influences C1 Domain Ligand Affinity and Membrane Interactions
Authors: Kelsey Jessica S. , Geczy Tamas , Lewin Nancy E. , Kedei Noemi , Hill Colin S. , Selezneva Julia S. , Valle Christopher J. , Woo Wonhee , Gorshkova Inna , Blumberg Peter M.
Published: April 2014

The C1 domain, which represents the recognition motif on protein kinase C for the lipophilic second messenger diacylglycerol and its ultrapotent analogues, the phorbol esters, has emerged as a promising therapeutic target for cancer and other indications. Potential target selectivity is markedly enhanced both because binding reflects ternary complex formation between the ligand, C1 domain, and phospholipid, and because binding drives membrane insertion of the C1 domain, permitting aspects of the C1 domain surface outside the binding site, per se, to influence binding energetics. Here, focusing on charged residues identified in atypical C1 domains which contribute to their loss of ligand binding activity, we showed that increasing charge along the rim of the binding cleft of the protein kinase C δ C1 b domain raises the requirement for anionic phospholipids. Correspondingly, it shifts the selectivity of C1 domain translocation to the plasma membrane, which is more negatively charged than internal membranes. This change in localization is most pronounced in the case of more hydrophilic ligands, which provide weaker membrane stabilization than do the more hydrophobic ligands and thus contributes an element to the structure–activity relations for C1 domain ligands. Coexpressing pairs of C1‐containing constructs with differing charges each expressing a distinct fluorescent tag provided a powerful tool to demonstrate the effect of increasing charge in the C1 domain.
The Role of Surface Hydrogen Atoms in the Electrochemical Reduction of Pyridine and CO2 in Aqueous Electrolyte
Authors: Lebègue Estelle , Agullo Julia , Morin Mario , Bélanger Daniel
Published: April 2014

The present study aims to get more insight into the role of pyridinium ions, surface H atoms and the nature of the electrode surface for the electrochemical reduction of CO2. The electrochemical activity of pyridinium ions in the absence and presence of CO2 is investigated on Ir, Pt, Au and glassy carbon electrodes. Glassy carbon and Au electrodes show irreversible reduction of pyridinium characterized by a cathodic peak potential. In the further presence of CO2, an increase of the current is noticed and the overall reduction process remains irreversible. In contrast, cyclic voltammograms recorded on an Ir electrode in a pyridine solution under nitrogen and CO2 are quasi‐reversible and consistent with the participation of H atoms adsorbed onto the electrode surface. Cyclic voltammograms for Ir and Pt electrodes are similar, as expected for metals with a strong affinity for hydrogen. Our results suggest that adsorbed H atoms may play a key role in the electrochemical reduction of CO2.
ChemInform Abstract: Twinned Caesium Cerium(IV) Pentafluoride.
Authors: Grzechnik Andrzej , Underwood Christopher C. , Kolis Joseph W.
Published: April 2014

Single crystals of CsCeF3 are prepared hydrothermally from a 1:5 molar mixture of CeF4 and CsF (autoclave, 250 °C, 1 d).
ChemInform Abstract: Crystal Growth Experiments in the Systems Ni2MSbO6 (M: Sc, In) Using Chemical Vapor Transport Reactions: Ni2InSbO6 and NiSb2O6 Crystals in the Millimeter Range.
Authors: Weil M. , Mathieu R. , Nordblad P. , Ivanov S. A.
Published: April 2014

Chemical vapor transport reaction of Ni2InSbO6 in the temperature gradient 1313 → 1233 K using HgCl2, HgBr2, PtCl2, or TeCl4 as transport agent leads to the growth of Ni2InSbO6 single crystals in the millimeter range.
ChemInform Abstract: Structural, Electronic and Optical Properties of Novel Carbonate Fluorides ABCO3F (A: K, Rb, Cs; B: Ca, Sr).
Authors: Narsimha Rao E. , Appalakondaiah S. , Yedukondalu N. , Vaitheeswaran G.
Published: April 2014

Properties of the title compounds are investigated by DFT calculations.
ChemInform Abstract: Drastic Change of Magnetic Interactions and Hysteresis Through Site‐Preferential Ru/Ir Substitution in Sc2FeRu5‐xIrB2.
Authors: Hermus Martin , Yang Minghui , Gruener Daniel , DiSalvo Francis J. , Fokwa Boniface P. T.
Published: April 2014

Sc2FeRu5‐xIrxB2 (x: 1, 2, 3, 4) are prepared by arc melting of the elements several times under Ar (20 s, 40 A).
ChemInform Abstract: Structural, Electronic and Magnetic Properties of the Series of Double Perovskites (Ca, Sr)2‐xLaxFeIrO6.
Authors: Bufaical L. , Adriano C. , Lora‐Serrano R. , Duque J. G. S. , Mendonca‐Ferreira L. , Rojas‐Ayala C. , Baggio‐Saitovitch E. , Bittar E. M. , Pagliuso P. G.
Published: April 2014

Polycrystalline samples of Sr2‐xLaxFeIrO6 with 0 ≤ x ≤ 2 are prepared by solid state reaction of stoichiometric mixtures of SrCO3, La2O3, Fe2O3, and Ir powder (air, 900 and 1100 °C for 24 h each).
ChemInform Abstract: Complex High‐Temperature Phase Transitions in Li2B12H12 and Na2B12H12.
Authors: Verdal Nina , Her Jae‐Hyuk , Stavila Vitalie , Soloninin Alexei V. , Babanova Olga A. , Skripov Alexander V. , Udovic Terrence J. , Rush John J.
Published: April 2014

Differential scanning calorimetry, X‐ray and neutron powder diffraction measurements of Li2B12H12 and Na2B12H12 indicate hysteretic transformations to high‐temperature phases at about 615 and 529 K, resp., upon heating from room temperature.
ChemInform Abstract: Phase Separation of a Hexacyanoferrate‐Bridged Coordination Framework under Electrochemical Na‐Ion Insertion.
Authors: Kajiyama Satoshi , Mizuno Yoshifumi , Okubo Masashi , Kurono Ryosuke , Nishimura Shin‐ichi , Yamada Atsuo
Published: April 2014

Eu[Fe(CN)6]·4H2O is precipitated from an aqueous solution of Eu(NO3)3 and K3Fe(CN)6 and used as an electrode in electrochemical Na intercalation.
ChemInform Abstract: Silica‐Supported Boric Acid Catalyzed Synthesis of Dihydropyrimidin‐2‐ones, Bis(indolyl)methanes, Esters and Amides.
Authors: Kumar Vishal , Singh Chitra , Sharma Upendra , Verma Praveen K. , Singh Bikram , Kumar Neeraj
Published: April 2014

Silica‐supported boric acid is found to be a green, efficient, and reusable catalyst for the synthesis of the title compounds under solvent‐free conditions.
ChemInform Abstract: Magnesium(II)‐Catalyzed Asymmetric Hetero‐Diels—Alder Reaction of Brassard′s Dienes with Isatins.
Authors: Zheng Jianfeng , Lin Lili , Kuang Yulong , Zhao Jiannan , Liu Xiaohua , Feng Xiaoming
Published: April 2014

The title reaction affords chiral spirolactones (III) and (V) bearing tetrasubstituted centers in high yields and stereoselectivities (up to 99% e.e.).
ChemInform Abstract: An Efficient Route for the Allylation of Arylaldehydes to give Enantiopure Homoallylic Alcohols.
Authors: Thorat Prashant B. , Goswami Santosh V. , Bhusare Sudhakar R.
Published: April 2014

Both enantiomers of the title compounds can be obtained by a simple change in the ligand structure under otherwise identical conditions.
ChemInform Abstract: Polyfluoro‐ and Perfluoroalkoxyenaminones in Syntheses of Nitrogen Containing Heterocycles.
Authors: Davydova Yulia A. , Sokolenko Taras M. , Yagupolskii Yurii L.
Published: April 2014

A simple method for the synthesis of enaminones (III) with poly‐ and perfluoroalkoxy groups at the 2‐position is developed.
ChemInform Abstract: Efficient Synthesis of 9,10‐Dihydrophenanthrene and 6H‐Benzo[c]chromene Derivatives via 6π Electrocyclization
Authors: Dhara Shubhendu , Gorai Tumpa , Ahmed Atiur , Ray Jayanta K.
Published: April 2014

of cyclic trienes
ChemInform Abstract: Prins Cyclization of α‐Bromoethers under Basic Conditions.
Authors: Arpin Patrice , Hill Bryan , Larouche‐Gauthier Robin , Spino Claude
Published: April 2014

α‐Bromoethers, generated from corresponding Mom‐acetals, undergo Prins‐type cyclization reactions under basic conditions without the need of any additional promoter.
ChemInform Abstract: Visible Light Enhanced Oxidant Free Dehydrogenation of Aromatic Alcohols Using Au—Pd Alloy Nanoparticle Catalysts.
Authors: Sarina Sarina , Bai Sagala , Huang Yiming , Chen Chao , Jia Jianfeng , Jaatinen Esa , Ayoko Godwin A. , Bao Zhaorigetu , Zhu Huaiyong
Published: April 2014

It is crucial that the reaction proceeds under visible light and in the presence of oxygen.
ChemInform Abstract: Highly Enantioselective Synthesis of Chiral Tetrahydroquinolines and Tetrahydroisoquinolines by Ruthenium‐Catalyzed Asymmetric Hydrogenation in Ionic Liquid.
Authors: Ding Zi‐Yuan , Wang Tianli , He Yan‐Mei , Chen Fei , Zhou Hai‐Feng , Fan Qing‐Hua , Guo Qingxiang , Chan Albert S. C.
Published: April 2014

This method uses chiral phosphine‐free Ru(diamine) complexes as catalysts which can be recycled 5‐6 times without a significant loss in activity.
ChemInform Abstract: One Pot Synthesis of Cyclohexanone Oxime from Nitrobenzene Using a Bifunctional Catalyst.
Authors: Rubio‐Marques Paula , Hernandez‐Garrido Juan Carlos , Leyva‐Perez Antonio , Corma Avelino
Published: April 2014

It is crucial to use supported gold and palladium on separated carbon particles to prepare the product in high yield.
ChemInform Abstract: A Two‐Step Synthesis of α‐Keto Vinyl Carbinols from Ketones.
Authors: Debien Laurent , Zard Samir Z.
Published: April 2014

An operationally simple reaction sequence for the synthesis of α‐keto vinyl carbinols is developed.
ChemInform Abstract: Phosphine‐Catalyzed Domino Reaction: A Novel Sequential [2 + 3] and [3 + 2] Annulation Reaction of γ‐Substituent Allenoates to Construct Bicyclic[3, 3, 0]octene Derivatives.
Authors: Li Erqing , Huang You
Published: April 2014

The relative stereochemistry of target compounds (III) (23 examples) is established using a combination of NMR spectroscopy and X‐ray analysis.
ChemInform Abstract: Enyne Metathesis Approach Towards the Cyclopentane Motif of Jatrophane Diterpenes.
Authors: Lentsch Christoph , Fuerst Rita , Rinner Uwe
Published: April 2014

The synthesis of the cyclopentane subunit (IV) of jatrophane diterpenes is described using Grubbs′ enyne metathesis of alkyne (I) and stereoselective Pd‐catalyzed ring opening of the epoxide (III) as key steps.
ChemInform Abstract: Syntheses of 3,4‐Disubstituted Pyrroles and Furans via Lewis Acid‐Promoted Semipinacol Rearrangement/Alkyne‐Ketone Metathesis Reaction of (C)‐2‐N‐ or O‐((3‐Arylpropargyl)methyl)‐Tethered 3,5,5‐Trimethyl‐2,3‐epoxycyclohexan‐1‐ones.
Authors: Yeh Ming‐Chang P. , Lin Ming‐Nan , Hsu Ching‐Hsien , Liang Chia‐Jung
Published: April 2014

The reaction starts with an acid‐promoted semipinacol rearrangement to give a cyclopentanone with an arylpropargylaminoacetyl side chain by ring contraction.
ChemInform Abstract: Palladium‐Catalyzed Aerobic Domino Oxidative Carbocyclization‐Alkynylation of Allenynes.
Authors: Volla Chandra M. R. , Baeckvall Jan‐E.
Published: April 2014

The reaction of the compounds (IX) is incomplete due to their increased steric hindrance.
ChemInform Abstract: Syntheses of Donor—Acceptor‐Functionalized Dihydroazulenes.
Authors: Broman Soeren Lindbaek , Jevric Martyn , Bond Andrew D. , Nielsen Mogens Broendsted
Published: April 2014

The dihydroazulene core is conveniently synthesized from malononitrile (I) and tropylium substrate (II).
ChemInform Abstract: Functionalization of Anthracene by Strategic Utilization of the Diels—Alder Reaction and the Ring‐Closing Metathesis.
Authors: Kotha Sambasivarao , Meshram Milind
Published: April 2014

A new route to synthesize 9,10‐bridged anthracene derivative (VIII) involving a ring‐closing metathesis reaction as key step is given.
ChemInform Abstract: Copper‐Catalyzed Asymmetric Propargylic Amination of Propargylic Acetates with Amines Using BICMAP.
Authors: Mino Takashi , Taguchi Hiroyuki , Hashimoto Masatoshi , Sakamoto Masami
Published: April 2014

The copper‐catalyzed asymmetric amination of propargylic acetates with (R)‐BICMAP as the catalyst is examined giving the corresponding tertiary amines with up to 90% e.e.
ChemInform Abstract: Synthesis of Fibrous Nano‐Silica‐Supported TEMPO and Its Application in Selective Oxidation of Alcohols.
Authors: Zhu Jie , Zhao Xue‐jing , Wang Peng‐cheng , Lu Ming
Published: April 2014

TEMPO supported on fibrous silica nanospheres is shown to be an efficient catalyst for the selective oxidation of (hetero)aromatic, aliphatic, allylic, and secondary alcohols.
ChemInform Abstract: Palladium‐ and Solvent‐Free Synthesis of Ynones by Copper(I)‐Catalyzed Acylation of Terminal Alkynes with Acyl Chlorides under Aerobic Conditions.
Authors: Mohammadi Elmira , Movassagh Barahman , Navidi Mozhgan
Published: April 2014

An easy, very efficient, and fast method for the cross‐coupling reaction of acyl chlorides with terminal alkynes is developed.
ChemInform Abstract: AIBN‐Initiated Metal Free Amidation of Aldehydes Using N‐Chloroamines.
Authors: Vanjari Rajeshwer , Guntreddi Tirumaleswararao , Singh Krishna Nand
Published: April 2014

Neither hydroxy‐ nor 2,4‐dichloro‐substituted benzaldehydes yield the corresponding amides.
ChemInform Abstract: A Mild, Chemoselective, One‐Pot Synthesis of δ‐Keto α‐Cyano Esters by Organocatalysis.
Authors: Liu Gang , Wang Yingcai
Published: April 2014

An efficient one‐pot synthesis of δ‐keto‐α‐cyano esters is achieved under mild conditions through sequential Knoevenagel—Michael reaction of α‐cyano esters.
ChemInform Abstract: Gold Catalyzed Synthesis of 3‐Alkoxyfurans at Room Temperature.
Authors: Pennell Matthew N. , Foster Robert W. , Turner Peter G. , Hailes Helen C. , Tame Christopher J. , Sheppard Tom D.
Published: April 2014

The reaction can be scaled up.
ChemInform Abstract: A Novel One‐Pot Sulfonyloxylactonization of Alkenoic Acids Mediated by Hypervalent Iodine Species Generated in situ from Ammonium Iodide.
Authors: Hu Jiantao , Zhu Min , Xu Yuan , Yan Jie
Published: April 2014

Scope and limitations of the novel method are established.
ChemInform Abstract: Enantioselective Michael Addition of Aldehydes to Maleimides Organocatalyzed by Chiral 1,2‐Diamines: An Experimental and Theoretical Study.
Authors: Avila Angel , Chinchilla Rafael , Gomez‐Bengoa Enrique , Najera Carmen
Published: April 2014

It is demonstrated, that enantiopure cyclohexane‐1,2‐diamine combined with hexanedioic acid as catalyst allows the asymmetric Michael addition of aliphatic aldehydes (I) to maleimides with up to 91% ee.
ChemInform Abstract: Chiral Squaramides Catalyzed Diastereo‐ and Enantioselective Michael Addition of α‐Substituted Isocyanoacetates to N‐Aryl Maleimides.
Authors: Zhao Mei‐Xin , Ji Fei‐Hu , Wei Deng‐Ke , Shi Min
Published: April 2014

The title reaction catalyzed by quinine (CSA) or cyclohexane‐1,2‐diamine (SAC) derived squaramide catalysts affords the corresponding adducts in good yields, high diastereoselectivities and good to excellent enantioselectivities under mild conditions.
ChemInform Abstract: Sequential Activation of σ‐Bonds: Intermolecular Cascade Annulation with Migration and Remote Functionalization.
Authors: Dhara Dipankar , Sengupta Tista , Khamarui Saikat , Ghosh Sukla , Maiti Dilip K.
Published: April 2014

CeCl3 enables selective C—C and C—N bond‐forming intermolecular cascade annulation between enamines and diaryl‐1,2‐diketones to furnish functionalized 3,3‐diarylpyrrolin‐2‐ones.
ChemInform Abstract: Copper‐Catalyzed Homocoupling of Ketoxime Carboxylates for Synthesis of Symmetrical Pyrroles.
Authors: Ran Longfei , Ren Zhi‐Hui , Wang Yao‐Yu , Guan Zheng‐Hui
Published: April 2014

In contrast to monoalkylmonoarylketoxime carboxylates, dialkylketoxime carboxylates do not react under the employed conditions.
ChemInform Abstract: Highly Diastereoselective Synthesis of 3‐Hydroxy‐2,2,3‐trisubstituted Indolines via Intramolecular Trapping of Ammonium Ylides with Ketones.
Authors: Jing Changcheng , Xing Dong , Hu Wenhao
Published: April 2014

Title compounds (III) and (V) are prepared via a Rh‐catalyzed reaction between either (E)‐styrenyl‐ or alkyl‐substituted 2‐aminophenyl ketones (I) and (IV) and diazo compounds (II).
ChemInform Abstract: Novel Isatin‐Based Hydroxamic Acids as Histone Deacetylase Inhibitors and Antitumor Agents.
Authors: Nam Nguyen‐Hai , et al. et al.
Published: April 2014

14 Title compounds of type (IV) or (VII) are prepared and tested as histone deacetylase (HDAC) inhibitors and antitumor agents.
ChemInform Abstract: Base‐Mediated Chemo‐ and Stereoselective Addition of 5‐Aminoindole/Tryptamine and Histamines onto Alkynes.
Authors: Verma Akhilesh K. , Patel Monika , Joshi Megha , Likhar Pravin R. , Tiwari Rakesh K. , Parang Keykavous
Published: April 2014

The stereochemistry of the products strongly depends on the reaction time.
ChemInform Abstract: Dearomatization of Tryptophols via a Vanadium‐Catalyzed Asymmetric Epoxidation and Ring‐Opening Cascade.
Authors: Han Long , Liu Chuan , Zhang Wei , Shi Xiao‐Xin , You Shu‐Li
Published: April 2014

Substrates bearing a methyl group at C5, C6, and C7‐positions require much longer reaction times.
ChemInform Abstract: Efficient Synthesis of 1,2‐Bis(alkoxycarbonyl)pyrazol‐3‐ones from 2,3‐Allenoic Acids, Azodicarboxylates and PPh3.
Authors: Lue Ruizhi , Cheng Xin , Zheng Xingliang , Ma Shengming
Published: April 2014

The structure of the product (IIIf) is confirmed by X‐ray analysis.
ChemInform Abstract: Efficient Iodine‐Catalyzed One Pot Synthesis of Highly Functionalized Pyrazoles in Water.
Authors: Srivastava Madhulika , Rai Pratibha , Singh Jaya , Singh Jagdamba
Published: April 2014

The reaction proceeds in water with I2 as a catalyst without any by‐product formation and the isolation of the product does not require a column chromatography.
ChemInform Abstract: 1,4‐Dialkyl‐1,4‐diazabutadienes: Their Reactions with Aluminum and Indium Halides.
Authors: Rojas‐Saenz Hector , Suarez‐Moreno Galdina V. , Ramos‐Garcia Iris , Duarte‐Hernandez Angelica M. , Mijangos Edgar , Pena‐Hueso Adrian , Contreras Rosalinda , Flores‐Parra Angelina
Published: April 2014

Diazabutadiene react with aluminum halides in toluene to furnish ionic aluminum coordination compounds [cf.
ChemInform Abstract: Synthesis of 2‐Methyl‐1‐[(5‐methylfuran‐2‐yl)methyl]‐ and 2‐Methyl‐1‐[(5‐methylpyrrol‐2‐yl)methyl]‐1H‐benzimidazoles.
Authors: Stroganova T. A. , Red'kin V. M. , Kovalenko G. A. , Vasilin V. K. , Krapivin G. D.
Published: April 2014

A straightforward route for the synthesis of the title furanylmethylbenzimidazoles (V) via cyclization of vicinal aminoanilides (IV) and its transformation into related pyrrolylmethylbenzimdazoles using a Paal—Knorr cyclization are described.
ChemInform Abstract: Activated Alumina Ball Catalyzed Expeditious Synthesis of 2‐Alkylbenzimidazoles with Special Emphasis on Susceptible Side Chains Possessing Amide Functionality.
Authors: Ghosh Sabari , Hudrlik Anne , Mukhopadhyay Chhanda
Published: April 2014

A green protocol for the solvent‐free synthesis of 2‐alkylbenzimidazoles under neutral conditions via alumina ball‐catalyzed condensation of o‐phenylenediamines with carboxylic acids is developed.
ChemInform Abstract: Palladium‐Catalyzed Decarboxylative C‐H Alkynylation of Benzoxazoles with α,β‐Ynoic Acids.
Authors: Kim Jinsik , Kang Dongjin , Yoo Eun Jeong , Lee Phil Ho
Published: April 2014

Heterocycles like imidazoles or thiazoles do not react under the present conditions.
ChemInform Abstract: Conjugated Nitroalkenes in Cycloaddition Reactions. Part 18. Regio‐ and Stereoselectivity of [2 + 3] Cycloaddition Reactions Between gem‐Chloronitroethene and (Z)‐C,N‐Diarylnitrones.
Authors: Jasinski R. , Mikulska M. , Koifman O. , Baranski A.
Published: April 2014

The title reaction leads to a stereoisomeric mixture of 3,4‐cis and 3,4‐trans‐2,3‐diaryl‐4‐chloro‐4‐nitroisoxazolidines (III)/(IV) with predominance of the cis‐isomer.
ChemInform Abstract: Copper‐Mediated Sequential C—N and N—N Bond Formation: Facile Synthesis of Symmetrical 1,2,4‐Triazoles.
Authors: Li Zhonglian , Zhang Zhiguo , Zhang Wei , Liu Qingfeng , Liu Tongxin , Zhang Guisheng
Published: April 2014

A convenient method for the dimerization of aromatic amidines to provide symmetrical triazoles is developed by using low‐toxic, stable, readily available, and inexpensive amidine hydrochlorides.
ChemInform Abstract: C—S Coupling Using a Mixed‐Ligand Pd Catalyst: A Highly Effective Strategy for Synthesizing Arylthio‐Substituted Heterocycles.
Authors: Cong Mei , Fan Yuting , Raimundo Jean‐Manuel , Xia Yi , Liu Yang , Quelever Gilles , Qu Fanqi , Peng Ling
Published: April 2014

For the first time a mixed‐ligand system, which can also activate C—Cl bonds in heteroaryl rings for C—S bond formation, is used in the title reaction.
ChemInform Abstract: Microwave‐Assisted Copper Azide Alkyne Cycloaddition (CuAAC) Reaction Using D‐Glucose as a Better Alternative Reductant
Authors: Kumar Yogesh , Bahadur Vijay , Singh Anil K. , Parmar Virinder S. , Singh Brajendra K.
Published: April 2014

30 examples
ChemInform Abstract: Synthesis and Antioxidant Activity of Bis and Tris Heterocycles.
Authors: Mahaboob Basha Nabhubygari , Seenaiah Dandu , Padmaja Adivireddy , Padmavathi Venkatapuram , Bhargav Desaraju Suresh , Vijaya Tartte
Published: April 2014

New compound (IIIa) displays radical scavenging activity in all the three tested methods greater than the standard ascorbic acid, and compounds (Va) and (VIIIa) show activities equal to the standard ascorbic acid.
ChemInform Abstract: Enantioselective N‐Heterocyclic Carbene Catalyzed Annulation Reactions with Imidazolidinones.
Authors: McCusker Elizabeth O'Bryan , Scheidt Karl A.
Published: April 2014

This highly selective carbene catalyzed reaction gives various differently substituted bicyclic lactones through a formal [4 + 2] annulation reaction.
ChemInform Abstract: A New Bis‐Fused π‐Electron Donor Composed of Tetrathiafulvalene and 2‐(Xanthen‐9‐ylidene)‐1,3‐dithiole.
Authors: Kato Minami , Shirahata Takashi , Misaki Yohji
Published: April 2014

4 Title compounds of type (III) are prepared.
ChemInform Abstract: An Efficient Green Multi‐Component Reaction Strategy for the Synthesis of Highly Functionalized Pyridines and Evaluation of Their Antibacterial Activities.
Authors: Srinivasula Reddy Lakkireddy , Ram Reddy Tirumalareddy , Mohan Reddy Bodireddy , Mahesh Avula , Lingappa Yeramanchi , Gangi Reddy Nallagondu Chinna
Published: April 2014

9 Title compounds of type (IV) are prepared by grinding the reaction components together with K2CO3 at room temperature and their antibacterial activities are screened.
ChemInform Abstract: A Study on the Selectivity of Arylzinc Reagents in Cross‐Coupling Reactions with Chemically Equivalent and Pseudo‐Equivalent Dibromopyridines.
Authors: Jung Hye‐Soo , Kim Seung‐Hoi
Published: April 2014

Site‐selective coupling reactions of aryl‐ and heteroarylzinc compounds with both chemically equivalent and pseudo‐equivalent carbon‐bromine compounds are investigated.
ChemInform Abstract: Rapid and Selective in situ Reduction of Pyridine‐N‐oxides with Tetrahydroxydiboron.
Authors: Londregan Allyn T. , Piotrowski David W. , Xiao Jun
Published: April 2014

Functionalization of pyridine‐N‐oxides and subsequent reduction provides 2‐substituted pyridines.
ChemInform Abstract: Iron‐Catalyzed Three‐Component Tandem Process: A Novel and Convenient Synthetic Route to Quinoline‐2,4‐Dicarboxylates from Arylamines, Glyoxylic Esters, and α‐Ketoesters.
Authors: Wei Wei , Wen Jiangwei , Yang Daoshan , Sun Xuejun , You Jinmao , Suo Yourui , Wang Hua
Published: April 2014

The new multicomponent reaction of aromatic amines, glyoxylic esters, and α‐ketoesters provides an attractive approach to a series of functionalized quinoline derivatives with promising unique pharmaceutical, biological, and fluorescence‐labeling applications.
ChemInform Abstract: Synthesis and Antimicrobial Activity of Pyrazolinone and Pyrazole Analogues Containing Quinoline Moiety.
Authors: Amir Mohd , Javed Sadique A. , Hassan Mohd Zaheen
Published: April 2014

New compound (IIId) is the most potent antimicrobial agent of the series showing broad spectrum antimicrobial activities.
ChemInform Abstract: Catalytic Enantioselective Synthesis of Functionalized Tropanes Reveals Novel Inhibitors of Hedgehog Signaling.
Authors: Narayan Rishikesh , Bauer Jonathan O. , Strohmann Carsten , Antonchick Andrey P. , Waldmann Herbert
Published: April 2014

A highly stereoselective [3 + 2] cycloaddition of fused azomethine ylides and nitroalkanes using a Cu(I)‐catalyst and (Rpl)‐FeSulPhos as chiral ligand is described.
ChemInform Abstract: Broensted Acidic Ionic Liquid Based Magnetic Nanoparticles: A New Promoter for the Biginelli Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones/thiones.
Authors: Safari Javad , Zarnegar Zohre
Published: April 2014

A Broensted acidic ionic liquid imidazolium hydrogen sulfate immobilized on magnetic Fe3O4 nanoparticles exhibits excellent catalytic activity in the Biginelli‐type synthesis of a diverse range of pyrimidine derivatives (IV).
ChemInform Abstract: Synthesis, Antiproliferative and Apoptosis‐Inducing Activity of Thiazolo[5,4‐d]pyrimidines.
Authors: Singh Baljinder , Guru Santosh K. , Kour Smit , Jain Shreyans K. , Sharma Rajni , Sharma Parduman R. , Singh Shashank K. , Bhushan Shashi , Bharate Sandip B. , Vishwakarma Ram A.
Published: April 2014

14 Title compounds of type (V) are prepared and tested for their antiproliferative and apoptosis‐inducing activities.
ChemInform Abstract: Synthesis of Pyrazolo[3,4‐d]‐4,5‐dihydropyrimidines Through [5 + 1] Cyclocondensation.
Authors: Ryabukhin Sergey V. , Granat Dmitry S. , Plaskon Andrey S. , Volochnyuk Dmitriy M. , Shivanyuk Alexander N.
Published: April 2014

More than twenty pyrazolodihydropyrimidine derivatives are prepared through condensation of secondary amidines with aromatic aldehydes in the presence of TmsCl as activator for the CO‐group and water scavenger.
ChemInform Abstract: New Method of Synthesis of 3,5,6,7‐Tetrahydro[1,2,4]triazolo[1,5‐a]pyrimidine‐2(1H)‐thione (VII)
Authors: Fizer M. M. , Slivka M. V. , Lendel V. G.
Published: April 2014

via electrophilic heterocyclization of 5‐allylaminotriazole derivative (IV)
ChemInform Abstract: Sodium Dodecylsulfate Induced Synthesis of Quinoxalines
Authors: Emmadi Narender Reddy , Atmakur Krishnaiah
Published: April 2014

via reaction of o‐phenylenediamine with phenacyl bromides (17 examples)
ChemInform Abstract: Reaction of 3‐Alkynylquinoxaline‐2‐carbonitriles with Sodium Azide: An Experimental and Theoretical Study.
Authors: Tyaglivy A. S. , Steglenko D. V. , Gulevskaya A. V.
Published: April 2014

Reaction of the title carbonitriles (I) with NaN3 in hot DMF results in the formation of substituted 2H‐1,2,3‐triazoles (II).
ChemInform Abstract: The [4 + 2] Cycloaddition of Donor—Acceptor Cyclobutanes and Nitrosoarenes.
Authors: Vemula Naresh , Stevens Andrew C. , Schon Tyler B. , Pagenkopf Brian L.
Published: April 2014

The Yb(OTf)3‐catalyzed [4+2]‐cycloaddition of the investigated cyclobutane derivative and nitrosoarenes proceeds regioselectively if no strongly electron withdrawing group (a regioisomer is formed) and no strongly electron donating group (no reaction) is present in the nitrosoarene.
ChemInform Abstract: Triazino Indole—Quinoline Hybrid: A Novel Approach to Antileishmanial Agents.
Authors: Sharma Rashmi , Pandey Anand Kumar , Shivahare Rahul , Srivastava Khushboo , Gupta Suman , Chauhan Prem M. S.
Published: April 2014

Most of the synthesized title compounds (III) (19 examples) are found to be active against intracellular amastigote form of Leishmania donovani.
ChemInform Abstract: 2,2‐Bis(trifluoromethyl)‐2,3‐dihydro‐1H‐1,5‐benzodiazepines
Authors: Petko K. I. , Vorobey V. M. , Gutov A. V. , Chernega A. N.
Published: April 2014

synthesis via cyclization of hexafluoroacetone N‐phenylimine derivatives (V)
ChemInform Abstract: Synthesis of 4‐Amino‐substituted Tetrahydropyrimido[4,5‐d]azocines.
Authors: Voskressensky L. G. , Ovcharov M. V. , Borisova T. N. , Listratova A. V. , Kulikova L. N. , Sorokina E. A. , Gromov S. P. , Varlamov A. V.
Published: April 2014

The synthesis of the title compounds (VII) involves the transformation of pyrimidines (I) into 4‐oxotetrahydropyrimidoazocines via reaction with alkynes and subsequent transformations of the 4‐oxopyrimidine fragment.
ChemInform Abstract: A Traceless Directing Group for C—H Borylation.
Authors: Preshlock Sean M. , Plattner Donald L. , Maligres Peter E. , Krska Shane W. , Maleczka Robert E. Jr. , Smith Milton R. III
Published: April 2014

A strategy is described for the regioselective substitution of a variety of N‐unsubstituted N‐heterocycles with HBpin.
ChemInform Abstract: Design, Synthesis, Antiviral, and Cytostatic Evaluation of Novel Isoxazolidine Analogues of C‐Nucleotides.
Authors: Grabkowska‐Druzyc Magdalena , Balzarini Jan , Piotrowska Dorota G.
Published: April 2014

A series of novel isoxazolidines (III) (25 examples), are prepared by a catalyst‐free 1,3‐dipolar cycloaddition reaction of nitrones (I) with styrenes (II).
ChemInform Abstract: Eudesmanolides and Guaianolides from Carpesium triste
Authors: Wu Hai‐Bo , Wang Wen‐Shu , Liu Ting‐Ting , Jiao Yu‐Guo
Published: April 2014

isolation and structure of new eudesmanolide (I) and guaianolides (II),(III)
ChemInform Abstract: New Dammarane‐Type Saponins from the Roots of Panax notoginseng
Authors: Qiu Li , Jiao Yang , Huang Gui‐Kun , Xie Ji‐Zhao , Miao Jian‐Hua , Yao Xin‐Sheng
Published: April 2014

isolation and structure elucidation
ChemInform Abstract: A New Friedelane Triterpene Ester (I) from Pouzolzia indica
Authors: Sarma Indrajit Sil , Dinda Biswanath
Published: April 2014

isolation and structure
ChemInform Abstract: A Diversity Oriented One‐Pot Synthesis of Novel Iminosugar C‐Glycosides.
Authors: Senthilkumar Soundararasu , Prasad Sure Siva , Kumar Ponminor Senthil , Baskaran Sundarababu
Published: April 2014

The reaction proceeds with complete regio‐ and stereoselectivity.
ChemInform Abstract: Chemoenzymatic Synthesis of 3′‐Deoxy‐3′‐(4‐substituted‐triazol‐1‐yl)‐5‐methyluridine.
Authors: Arya Anu , Mathur Divya , Tyagi Abhilash , Kumar Rajesh , Kumar Vinod , Olsen Carl E. , Saxena Rajendra K. , Prasad Ashok K.
Published: April 2014

A series of triazoles (III) (9 examples) is readily synthesized by a Huisgen 1,3‐dipolar cycloaddition reaction of alkynes (II) with azide (I), which is chemoenzymatically prepared starting from D‐xylose.
ChemInform Abstract: New Orsellinic Acid Esters from Fungus Chaetomium globosporum.
Authors: Xu Guo‐Bo , Wang Ni‐Ni , Bao Jin‐Ku , Yang Tao , Li Guo‐You
Published: April 2014

Orsellinic acid esters (I)—(VII) are obtained along with four known compounds from the solid, fermented rice culture of Chaetomium globosporum (cib‐132).