Analysis of clinical parameters of white spots on young permanent teeth after their treatment with different dental varnishes
Authors: Knežević Ranka , Vojinović Jovan 
Published: September 2022

&lt;p&gt;&lt;strong&gt;&lt;span id=&quot;page764R_mcid5&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 424.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(1.07883);&quot; role=&quot;presentation&quot;&gt;Introduction&lt;/span&gt;&lt;/span&gt;&lt;/strong&gt;&lt;span id=&quot;page764R_mcid6&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 486.074px; top: 424.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.945554);&quot; role=&quot;presentation&quot;&gt;&lt;strong&gt;.&lt;/strong&gt; Detection of early carious lesion and its remineraliza&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid8&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 444.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.984641);&quot; role=&quot;presentation&quot;&gt;tion is the most effective way for caries treatment. The aim of this &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid9&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 464.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.930975);&quot; role=&quot;presentation&quot;&gt;study is to compare effectiveness of remineralization of the early car&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid11&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 484.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.944369);&quot; role=&quot;presentation&quot;&gt;ious lesions with different fluoride varnishes.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span id=&quot;page764R_mcid12&quot; class=&quot;markedContent&quot;&gt;&lt;strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 514.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(1.05127);&quot; role=&quot;presentation&quot;&gt;Method&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid13&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 450.559px; top: 514.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.93636);&quot; role=&quot;presentation&quot;&gt;&lt;strong&gt;. &lt;/strong&gt;The research included 30 children, girls and boys, aged 12 &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid14&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 534.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.929762);&quot; role=&quot;presentation&quot;&gt;and 13, in whom the presence of white lesions on at least two vestib&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid16&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 554.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.963568);&quot; role=&quot;presentation&quot;&gt;ular surfaces was detected on 60 permanent teeth during a clinical &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid17&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 574.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.925059);&quot; role=&quot;presentation&quot;&gt;examination by visual method. Gingival status was determined based &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid18&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 594.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.987576);&quot; role=&quot;presentation&quot;&gt;on bleeding or non-bleeding after probing, activity of the white le&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid20&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 614.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.930098);&quot; role=&quot;presentation&quot;&gt;sion was visually examined and the size of the lesion was measured. &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid21&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 634.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.952746);&quot; role=&quot;presentation&quot;&gt;After the measurement, the application of varnishes was performed &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid22&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 654.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.951335);&quot; role=&quot;presentation&quot;&gt;by the procedure that two different dental varnishes were applied to &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid23&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 674.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.98443);&quot; role=&quot;presentation&quot;&gt;two different teeth with white lesion in the same person: group I &amp;ndash;&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid24&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 694.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.982215);&quot; role=&quot;presentation&quot;&gt;fluoride varnish with 1.5% non-organic ammonium fluoride, group &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid25&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 714.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.951151);&quot; role=&quot;presentation&quot;&gt;II &amp;ndash; fluoride varnish enriched with minerals with 5% sodium fluoride. &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid26&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 734.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.960597);&quot; role=&quot;presentation&quot;&gt;Activity, lesion dimensions and gingival status were examined after &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid27&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 754.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.934337);&quot; role=&quot;presentation&quot;&gt;four, eight and twelve weeks when new varnishes were also applied.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span id=&quot;page764R_mcid28&quot; class=&quot;markedContent&quot;&gt;&lt;strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 783.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.964007);&quot; role=&quot;presentation&quot;&gt;Results&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid29&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 445.692px; top: 783.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(1.01556);&quot; role=&quot;presentation&quot;&gt;&lt;strong&gt;.&lt;/strong&gt; Inactivation of white lesions was recorded in the eighth &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid30&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 803.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(1.03667);&quot; role=&quot;presentation&quot;&gt;week, but statistically significant difference was recorded after &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid31&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 823.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.931813);&quot; role=&quot;presentation&quot;&gt;twelve weeks with 56.2% inactive lesions in the group I and 57.5% in &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid32&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 843.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.925568);&quot; role=&quot;presentation&quot;&gt;the group II. There was no recorded difference in the lesion activity of &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid33&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 863.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.928553);&quot; role=&quot;presentation&quot;&gt;the varnishes. Changes in the gingivo-incisal diameter during the vis&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid35&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 883.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.935228);&quot; role=&quot;presentation&quot;&gt;its amounted to: 3.47 mm/3.59 mm/3.53 mm/3.46 mm for the group I &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid36&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 903.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.921688);&quot; role=&quot;presentation&quot;&gt;and 3.21 mm/3.19 mm/3.18 mm/3.20 mm for the group II. Changes in &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid37&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 923.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.94927);&quot; role=&quot;presentation&quot;&gt;mesio-distal diameter amounted to: group I: 2.94 mm/2.81 mm/2.84 &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid38&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 943.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.942486);&quot; role=&quot;presentation&quot;&gt;mm/2.4 mm; group II: 2.94 mm/2.87 mm/2.89 mm/2.90 mm. Statisti&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid40&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 963.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.955187);&quot; role=&quot;presentation&quot;&gt;cally significant difference in both diameters was recorded between &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid41&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 983.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.910905);&quot; role=&quot;presentation&quot;&gt;the first and second visit in the group I (p = 0.0046). There was no sta&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid43&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1003.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.982722);&quot; role=&quot;presentation&quot;&gt;tistically significant difference recorded in the group I during other &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid44&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1023.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.944744);&quot; role=&quot;presentation&quot;&gt;visits. In the group II statistically significant differences in the chang&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid46&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1043.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.938884);&quot; role=&quot;presentation&quot;&gt;es of lesion dimension were not recorded. Statistically significant dif&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid48&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1063.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.924091);&quot; role=&quot;presentation&quot;&gt;ferences p&amp;lt; 0.001 were recorded in the presence of gingival bleeding &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid49&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1083.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.984019);&quot; role=&quot;presentation&quot;&gt;between the examined groups at the first visit, where significantly &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid50&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1103.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.935549);&quot; role=&quot;presentation&quot;&gt;more lesions with healthy gingiva were observed in group I (84.4%).&lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span id=&quot;page764R_mcid51&quot; class=&quot;markedContent&quot;&gt;&lt;strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1132.99px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.994541);&quot; role=&quot;presentation&quot;&gt;Conclusion&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid52&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 474.108px; top: 1132.99px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.921876);&quot; role=&quot;presentation&quot;&gt;&lt;strong&gt;.&lt;/strong&gt; Dental fluoride varnishes cause remineralization of early &lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid53&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1152.99px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.971069);&quot; role=&quot;presentation&quot;&gt;carious lesion after twelve weeks without significant difference be&lt;/span&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid54&quot; class=&quot;markedContent&quot;&gt;&lt;/span&gt;&lt;span id=&quot;page764R_mcid55&quot; class=&quot;markedContent&quot;&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 392.126px; top: 1172.99px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.921841);&quot; role=&quot;presentation&quot;&gt;tween classic and enriched varnishes.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;