bluuebunny/crossref_metadata_2025 huggingface dataset:
Cost-utilities Analysis of Polatuzumab Vedotin Combined with Bendamustine and Rituximab for Relapsed/Refractory Diffuse Large B-cell Lymphoma Which Is Unsuited for Hematopoietic Stem Cell Transplantation
Authors: Yang Lan , Ma Aixia
Published: April 2023

Objectives To evaluate the cost-utilities of Polatuzumab Vedotin (Polivy) combined with bendamustine and rituximab regimen (BR) for relapsed/refractory diffuse large B-cell lymphoma (DLBCL) which is unsuited for hematopoietic stem cell transplantation. Methods From the perspective of the China 's health system, the cost-utilities analysis of BR regimen combined with Polatuzumab Vedotin (Polivy) and BR regimen alone for relapsed/refractory DLBCL which is unsuited for hematopoietic stem cell transplantation was analyzed by using partitioned survival model (PSM). Results Compared with BR regimen alone, BR regimen combined with Polatuzumab Vedotin (Polivy) for relapsed/refractory DLBCL which is unsuited for hematopoietic stem cell transplantation patients can increase 1.1706 QALYs in 15 years, the total cost is increased by 231 117.9 yuan, and the ICUR value is 197 434.7 yuan/QALY. The sensitivity analysis confirmed the robustness of the results. Conclusion In the long run, compared with BR alone, BR combined with Polatuzumab Vedotin (Polivy) doesn’t have cost-effectiveness advantages for relapsed/refractory DLBCL which is unsuited for hematopoietic stem cell transplantation patients.
Research and Analysis of Economic Factors Affecting Subjective Quality of Life of County Residents: The Study of Fengyang County
Authors: Xiang Tingyu
Published: April 2023

The nowadays cutting-edge trend in research on quality of life is to combine objective evaluations with subjective perceptions, one without the other. Subjective quality of life evaluation plays a greater role in understanding people's satisfaction with life, and therefore has gained widespread attention from the academic community. However, at present, the research on people's quality of life in China still mainly focuses on objective evaluation, leaving a lack of relevant facts and data to support subjective perceptions. This paper takes Fengyang County as a case study to investigate the local people's feelings about consumption, housing, education, health care and transportation, summarizing the influence of economic factors on them and their connections.
Research on the Construction Path of Digital Audit
Authors: Gao Zhenzhen
Published: April 2023

Audit informatization is an imperative revolution. Under the new social situation, in order to continuously improve the audit efficiency and audit quality, the construction of digital audit platform and its related credit system is particularly important. This paper mainly combines the current advanced digital technology with the specific process of audit work. This paper discusses how to construct the digital audit platform and the related credit system effectively to provide the development direction for the high quality development of audit work.
Analysis of Strategic Human Resource Management Practices
Authors: Zhang Jinlan
Published: April 2023

In the hospitality industry, human resources are considered one of the most essential and significant resources. This report aims to explore the influence of strategic human resource management through analysing three main HR strategies of Hilton Worldwide on achieving organisational goals and performance. And three models including resource-based view, best practice model, and best fit model will be adopted in the case analysis. It is hoped that this report will provide some insight for hotel enterprises and can indicate a direction for future study with comparison of other valuable human resources strategies.
The Study of The Economic Distribution Characteristics of Night Economic Distribution Based on Multi-source Data Fusion
Authors: Zhou Yixuan , Geng Yuehua
Published: April 2023

The night economy is an important representation of urban economic development and consumption level. Based on the night lighting, the data of the POI data, the data of the spatial clustering algorithm of DBSCAN、K-means and other spatial clustering algorithms and the study of the profit and loss of supply and demand, the model of the area and the area domain analysis of the night activity hotspot area and night service facility are established. The fusion of multi-source data provides a new perspective for the night economy, which is more rapid, efficient and extensive than the traditional survey data, which is suitable for the large-scale study of the night economy.
Aceros inoxidables dúplex sometidos a medios corrosivos
Authors: Saénz A. Laura P. , Carabaño G. María V.
Published: April 2023

Los aceros inoxidables dúplex son materiales de construcción muy atractivos para su uso en entornos agresivos debido a sus varias ventajas sobre los  aceros inoxidables austeníticos. Los  aceros dúplex tienen una  excelente resistencia a  la corrosión por picaduras y grietas, son altamente resistentes al agrietamiento por corrosión bajo tensión de cloruro y son aproximadamente el doble de fuertes que los aceros austeníticos comunes. Mejores propiedades están asociadas con sus microestructuras que consisten en granos de ferrita y austenita. Sin embargo, con ciertos a someterse a medios agresivos, estas excelentes  propiedades pueden reducirse  debido a cambios no deseados en la  microestructura del acero, relacionados  principalmente  con  destrucción de las fases por la perdida de los elementos níquel y cromo. Se investigó la perdida de peso e incremento de velocidad de corrosión de los aceros inoxidables dúplex 2205, 2507 y 2304.  Los tres tipos de aceros dúplex fueron expuestos a medios corrosivos tales como: ácido nítrico, ácido clorhídrico, ácido sulfúrico, ácido oxálico, cloruro de sodio y sulfato férrico. Se realizaron exámenes con microscopio de luz, un Microscopio Electrónico de Barrido con Espectroscopia Dispersa de Rayos X. El objetivo principal de las investigaciones fue determinar el efecto del  medio corrosivo sobre los aceros, evaluando la perdida de peso, velocidad de corrosión  y los cambios en la microestructura.
Evaluación del proceso de descrude y blanqueamiento de algodón hidrófilo aséptico a escala industrial
Authors: Hurtado Vanessa , Medina Rauddy , Ojeda Jesús , Cordero Cristina , Almarza--Morales Ángel
Published: April 2023

Las etapas de descrude y blanqueamiento del algodón resultan ser críticas dentro del proceso productivo por cuanto son determinantes en el alcance de los parámetros de calidad y especificaciones como la apariencia, la presencia de sustancias grasas y la absorbencia que según normas COVENIN 2982 deben cumplirse para su comercialización. En tal sentido, en este trabajo se evalúa el comportamiento que sobre estas características ejerce el tiempo de exposición en cada etapa y las proporciones de los reactivos empleados en un proceso real. Así, el factor fundamental que afecta la etapa de descrude es la cantidad de soda cáustica; mientras que la cantidad de humectante, peróxido, y la interacción de la temperatura con la soda cáustica, son los que afectan la etapa de blanqueo.
Applications of Augmented Reality in Orthopaedic Spine Surgery
Authors: Shahzad Hania , Bhatti Nazihah S. , Phillips Frank M. , Khan Safdar N.
Published: April 2023

The application of augmented reality (AR) in surgical settings has primarily been as a navigation tool in the operating room because of its ease of use and minimal effect on surgical procedures. The surgeon can directly face the surgical field while viewing 3D anatomy virtually, thus reducing the need to look at an external display, such as a navigation system. Applications of AR are being explored in spine surgery. The basic principles of AR include data preparation, registration, tracking, and visualization. Current literature provides sufficient preclinical and clinical data evidence for the use of AR technology in spine surgery. AR systems are efficient assistive devices, providing greater accuracy for insertion points, more comfort for surgeons, and reduced operating time. AR technology also has beneficial applications in surgical training, education, and telementorship for spine surgery. However, costs associated with specially designed imaging equipment and physicians' comfort in using this technology continue to remain barriers to its adoption. As this technology evolves to a more widespread use, future applications will be directed by the cost-effectiveness of AR-assisted surgeries.
Irakaskuntzarako bideoak: zergatiak, irizpideak eta gidalerroak
Authors: Arroyo Amaia
Published: April 2023

Egun, gutxiago irakurtzen dugun ideia bolo-bolo dabil: liburu gutxiago, aldizkari gutxiago… Informazio gutxiago jasotzen al dugu? Argi dago ezetz. Informazioa inoiz baino saretuago dagoen momentu honetan, bistakoa da edukiak kontsumitzeko ohiturak aldatu egin direla, oro har. Ikus-entzunezko komunikazioa edo komunikazio digitala da hedatuen dagoena, testu idatzitik harago doana, hain zuzen ere, eta bideoa da horren adibiderik garbiena. Hezkuntza-esparruak ezin dio muzin egin agertoki berri horri eta hezkuntza-jardunean bideoak txertatzeko ahalegina egin beharko litzateke. Artikulu honen helburua da horretarako irizpideak eta gidalerroak eskaintzea.
Perception of Senior High School Learners in Selected Northern Cebu Provinces towards Bachelor of Science in Fisheries: Inputs for Marketing Interventions
Authors: Porlas Ana Aubrey J , Abucay Manilyn M , Antolijao Teofilo D , Roble Noel D , Lamayo Ma Helian A
Published: April 2023

The study sought to characterize and determine the level of perception of Senior High School students on the degree program Bachelor of Science in Fisheries based on different perception domains as anchored from the Human Capital Theory of Becker, Signal Theory of Spence, Certificate Theory of Collins, and Search and Matching Theory of Diamond and Mortensen. Career Guidance Program and short infomercial videos have been proposed based on the findings. This study utilized a descriptive-quantitative research design using researcher-made questionnaires via purposive sampling of 304 respondents that were implemented online and physically in the selected provinces in the northern part of Cebu, Philippines. Processing of data involved frequency, simple percentage, ranking, simple average, weighted mean, and standard deviation. Findings suggest that majority of the respondents aim for business-related degrees, followed by health sciences and engineering. Awareness of existing fisheries academes, facilities in Northern Cebu, worker population, fisheries-related laws and government agencies is limited. Respondents expressed particular interest on the degree program in terms of participation on orientation, aquaculture, post-harvest processing, affordability, employment opportunities, stability, career-related job as water and soil technicians, immediate employment with less competition, promotions, and teaching opportunities as graduates. Respondents noted the program’s potential to help communities and small-scale fishing farmers and the potential pride of being a BS in Fisheries graduate.
Nhận dạng thực thể được đặt tên trong văn bản Tiếng Việt sử dụng học máy và ứng dụng trong đảm bảo an ninh mạng
Authors: Toàn Nguyễn Ngọc , Tuấn Lê Xuân , Dũng Lương Thế , Phú Trần Nghi
Published: April 2023

Tóm tắt—  Nhận dạng thực thể được đặt tên (hoặc “được gán nhãn”: Named Entity Recognization - NER) trong văn bản Tiếng Việt hiện đang là một bài toán có nhiều thách thức do không có nhiều tập dữ liệu chuẩn hoặc có nhưng chưa đủ lớn và các mô hình nhận dạng thường được xây dựng chủ yếu dựa trên phương pháp học sâu. Trong bài báo này, nhóm tác giả trình bày một cách tiếp cận có hệ thống trong việc xây dựng mô hình nhận dạng thực thể của các văn bản Tiếng Việt, từ bước thu thập, xây dựng tập dữ liệu cho đến áp dụng, tinh chỉnh các mô hình học máy. Đặc biệt, nhóm tác giả cũng đề xuất các kịch bản ứng dụng và chứng minh khả năng áp dụng mô hình nhận dạng thực thể được đặt tên hiệu quả trong giải quyết các bài toán đảm bảo an ninh, an toàn thông tin mạng. Cụ thể, nhóm tác giả xây dựng tập dữ liệu gồm hơn 5000 văn bản thu thập từ các mạng xã hội sử dụng Tiếng Việt, đặt tên và gán 1 trong 4 nhãn định trước cho các thực thể; sau đó, áp dụng mô hình huấn luyện trước XLM-RoBERTa với các tham số ban đầu được tinh chỉnh phù hợp để nhận dạng các thực thể này. Kết quả thử nghiệm cho thấy hệ thống là hiệu quả với khả năng nhận dạng thực thể của mô hình và đạt độ đo F1- measure lên đến 95.6%, trội hơn so với một số hệ thống NER cho văn bản Tiếng Việt trên cùng tập dữ liệu mà nhóm tác giả đã xây dựng. Mô hình đề xuất cũng đã được ứng dụng trong xây dựng các hệ thống hỗ trợ đảm bảo an ninh mạng hiện nay.
Abstract— Named Entity Recognition (NER) in Vietnamese documents is currently a challenging task because of the lacking of standard datasets, or these datasets might be not large enough. Moveover, recognition models are often built mainly based on deep learning methods. In this paper, we present a systematic approach in building entity recognition models of Vietnamese documents, beginning with collecting and building data sets then applying and refining machine learning models. In addition to that, we also propose some scenarios of application which proof the capability of our model in dealing with information security problems. Specifically, we built a dataset of more than 5000 documents collected from social networks using Vietnamese, naming and assigning 1 of 4 predefined labels to the entities in the documents and then apply the pre-training model XLM-RoBERTa with the appropriate fine-tuned initial parameters to recognize these entities. Preliminary results show that the proposed system is effective with the ability to recognize the entity of the model and achieve the F1- measure up to 95.6%, which is better than some NER systems curently available for Vietnamese documents on the same dataset which we have built. The proposed model has been used in building support systems for cybersecurity protection currently.
Đề xuất tầng tuyến tính và đánh giá khả năng cài đặt trong xây dựng mã khối 256 bit có cấu trúc FLC
Authors: Nam Trần Sỹ , Long Nguyễn Văn , Cương Nguyễn Bùi
Published: April 2023

Tóm tắt— Trong bài báo này, nhóm tác giả đề xuất tầng tuyến tính an toàn và hiệu quả trong cài đặt để hướng tới việc xây dựng mã khối kích thước 256-bit có tên là FLC. Cụ thể, nhóm tác giả đã sinh ra ma trận MDS kích thước 8×8 có dạng lũy thừa của ma trận đồng hành trên trường hữu hạn. Khi xem xét sử dụng ma trận này trong xây dựng mã khối 256-bit có cấu trúc FLC, nhóm tác giả thực hiện đánh giá khả năng cài đặt của quá trình mã hóa/giải mã trên nhiều nền tảng khác nhau. Các kết quả thực nghiệm chỉ ra rằng cài đặt của mã khối với đề xuất này hoàn toàn phù hợp để tích hợp trong các ứng dụng thực tế.
Abstract— In this paper, we propose a secured and efficient linear diffusion layer that suitable for block cipher with 256-bit block size named FLC.  Specifically, we have generated an 8×8 MDS matrix that has the power of a companion matrix over a finite field. We also perform a performance evaluation of the encryption/decryption process on various platforms. Our experimental results show that block cipher with our proposed linear diffusion layer is perfectly suitable for real life applications.
Xây dựng bộ thư viện người dùng cho card tăng tốc mã hóa qua giao tiếp PCIe
Authors: Cường Vũ Tá , Kỷ Phan Văn
Published: April 2023

Tóm tắt — Thiết bị mã hóa tốc độ cao sử dụng giao tiếp PCIe được phát triển rất đa dạng và được thương mại hóa từ lâu với mục đích tăng tốc độ xử lý mã hóa/giải mã và che giấu thuật toán, tham số mật mã. Trong bài báo [1], nhóm tác giả đã giới thiệu giải pháp thiết kế card tăng tốc mã hóa PCIe sử dụng công nghệ FPGA. Trong bài báo này, nhóm tác giả sẽ giới thiệu giải pháp xây dựng bộ thư viện người dùng cho card tăng tốc mã hóa PCIe. Bộ thư viện này sẽ có các hàm chức năng giúp các ứng dụng, phần mềm trên máy tính sử dụng card tăng tốc PCIe một cách linh hoạt, thuận tiện.
 
Abstract— High-speed encryption device using PCIe interface has been developed and commercialized for a long time with the purpose of speeding up encryption/decryption processing and hiding algorithms and cryptographic parameters. In the article [1], the authors introduced a solution to design a PCIe cryptographic accelerator using FPGA technology. In this paper, the authors introduce a solution to build a user library for PCIe cryptographic accelerator. This library set will have functions to help applications and software on computers use PCIe acceleration cards flexibly and conveniently.
Áp dụng học tăng cường trong kiểm thử xâm nhập tự động
Authors: Hùng Nguyễn Việt , Công Nguyễn Thành
Published: April 2023

Tóm tắt— Đối mặt với những nguy cơ mất an toàn thông tin ngày càng đa dạng và thường xuyên hiện nay, kiểm thử xâm nhập là một phương pháp đánh giá an toàn cho các hệ thống thông tin được các tổ chức ưu tiên thực hiện. Kiểm thử xâm nhập thường được thực hiện thủ công bởi các kiểm thử viên và có thể phát hiện những lỗi nghiêm trọng và các vấn đề về an toàn thông tin. Tuy nhiên, phương pháp này đòi hỏi nhiều công sức, đồng thời yêu cầu kiểm thử viên phải có trình độ, kinh nghiệm thực tế cao. Một trong những hướng nghiên cứu được quan tâm gần đây là xây dựng các phương pháp hỗ trợ đánh giá kiểm thử tự động. Kỹ thuật phân tích đồ thị tấn công và thuật toán học tăng cường đã được một số nhóm nghiên cứu trên thế giới sử dụng trong xây dựng công cụ đánh giá kiểm thử tự động. Trong bài báo này, nhóm tác giả đề xuất mô hình dựa trên thuật toán học tăng cường và phương pháp tối ưu hóa tham số cho mô hình này trong đánh giá kiểm thử tự động. Để đánh giá mô hình đề xuất, ngoài bộ dữ liệu dựa trên phương pháp được các nhóm nghiên cứu khác sử dụng, chúng tôi còn đánh giá trên bộ dữ liệu (dataset) tự xây dựng trên các môi trường thực tế với các lỗ hổng bảo mật cập nhật. Các kết quả thực nghiệm cho thấy phương pháp đề xuất đưa ra các đánh giá tốt hơn các phương pháp khác.
Automated Test Data Generation for Embedded System Models Using Combinatorial Testing
Authors: Ngoc Do Thi Bich
Published: April 2023

Abstract— Embedded systems have been playing very important roles in modern society. They have appeared in every aspect of life from automotive to avionics industries to home appliances, etc. These embedded systems therefore must satisfy high quality requirements. As a consequence, quality assurance for these kinds of systems has attracted much attention and investment from both academic research and industry communities. In developing embedded systems, testing often requires high coverage with different measures with respect to international standards like Decision Coverage (DC), Condition Coverage (CC), Modified Condition/Decision Coverage (MC/DC) respected to ISO 26262. However, it is difficult to generate test cases with high coverage due to the complexity of the embedded system, the larger number of inputs, and the complex continuous signals of inputs.
In order to have good test cases with high DC, CC, MC/DC coverage measures, this paper proposes a method to automatically generate test-cases by applying Combinatorial testing technique. The requirements of the inputs of the embedded model will be encoded to the input of Combinatorial testing technique in order to generate test cases that cover all pair values of any two inputs. Experiments on case studies showed that proposed method has coverage result better than that of the random testing method.
Geração "nem-nem" na pandemia de COVID-19: Uma abordagem com regressões logísticas
Authors: Paula Junior Amarildo de , Wroblevski Bruno
Published: April 2023

A pandemia de COVID-19 acarretou amplas mudanças na economia brasileira e, dentre os impactos negativos no mercado de trabalho, pode-se citar o crescimento da parcela de jovens que não estudam e nem trabalham, condição conhecida como jovem “nem-nem”. Nesse sentido, este estudo tem como objetivo analisar quais fatores discutidos pela literatura afetam a condição “nemnem” dos indivíduos jovens durante o cenário pandêmico. Para isso, foram aplicadas regressões logísticas binomiais e multinomiais nos dados referentes ao ano de 2020 da PNAD COVID-19. Os resultados encontrados por meio do Logit Binomial indicam que fatores familiares e de habilidade afetam negativamente a posição do jovem brasileiro como um “nem-nem”. Por outro lado, fatores pessoais, como a idade do jovem, e fatores relacionados à benefícios sociais influenciam positivamente o jovem brasileiro a ter um status “nem-nem”. Em relação aos resultados obtidos por meio do Logit Multinomial, verifica-se que ser da região Norte ou Nordeste eleva a chance de o jovem não estudar e também estar na condição de desemprego em comparação à região Sudeste. Mas ocorre o inverso quando se considera o jovem que não estuda e está desalentado.
Análise setorial dos diferenciais de rendimentos entre os gêneros no Rio Grande do Sul: Uma abordagem paramétrica e não paramétrica
Authors: De Oliveira Dobner Luana , Da Rocha Gonçalves Rodrigo , Mesquita Pereira Rafael
Published: April 2023

O objetivo deste artigo é analisar setorialmente os diferenciais de rendimentos entre os gêneros no estado do Rio Grande do Sul. Para tanto, utilizando dados da Relação Anual de Informações Sociais (RAIS) dos anos de 2012 a 2018, são estimadas as decomposições de Oaxaca (1973) e Blinder (1973) e de Ñopo (2008), com o intuito de verificar a existência ou não de um possível diferencial de rendimentos entre mulheres e homens no mercado de trabalho gaúcho, assim como a magnitude deste provável hiato. Os resultados indicam a presença de discriminação de rendimentos no referido mercado em favor dos homens em todos os setores analisados. Além disso, observa-se que se os atributos produtivos determinassem o padrão salarial, as mulheres ganhariam mais que os homens, evidência essa constatada em ambas as decomposições. Por fim, ressalta-se a importância da verificação dos resultados realizada a partir das abordagens paramétrica (Oaxaca-Blinder) e não paramétrica (Ñopo).
Representation of Korean Women's Beauty in K-Natural White Brightening Body Wash Self-care Ads on Television Media
Authors: Sekaranti Dinda Ayu , Kartikasari R.A. Loretta
Published: April 2023

The Financial Services Authority or “Otoritas Jasa Keuangan, (OJK)” was formed with the aim that all activities in the financial services sector: are organized regularly, fairly, transparently and accountably, are able to realize a financial system that grows in a sustainable and stable manner, and is able to protect the interests of consumers and the public. The duties, functions, and authorities of the OJK are very heavy and complex because they are related to regulation and supervision in the field of financial services. The implementation of OJK's duties, functions, and authorities in regulating and supervising the financial services sector needs to be supported by the availability of OJK employees who have competence in accordance with developments in the financial services sector. The competence of OJK employees must include a combination of skills, knowledge, and attitudes, namely: Technical Competence or technical competence, Managerial Competence or managerial competence, Interpersonal Competence or Social/Communication Competence. The method in this writing uses a literature study, by examining: books, scientific journals, laws and regulations, online materials, and other sources.
Analysis of Digital Marketing Strategy on Product Sales
Authors: Muhtar Hari Mega , Effendi Adang Djatnika , Burhan Leni
Published: April 2023

This journal article discusses the analysis of digital marketing strategies on product sales of PT Ousean Group. This study was conducted by using the method of observation and documentation. The source of the data comes from the results of observations and company documentation obtained online. This type of data is in the form of good information about the digital marketing strategy used by the company. The data collection technique was carried out by means of observation, namely systematic observation and recording and document technique, namely the collection of previous documents in the form of writing, drawings or monumental works. Data analysis techniques are carried out by interpreting data containing information on the company's digital marketing strategy.
ANALYSIS OF FINANCIAL STATEMENTS TO MEASURE THE EFFECTIVENESS OF THE COMPANY'S FINANCIAL PERFORMANCE IN PT. RETABTAMA
Authors: Martika Yeni Lasmayanti , Ruhenda
Published: April 2023

This research was conducted with the aim of ensuring the company's financial flow and the extent to which the company's effectiveness and efficiency in using its resources, as well as the good and bad financial conditions at PT. Retabtama. The research method carried out in this study uses a quantitative research approach the data collection technique used is the documentation method, in which the researcher obtains data on the company's financial statements and other information related to the company. And the data analysis technique used in measuring the company's financial performance is to use of an analytical tool in the form of financial ratios. In measuring the company's financial performance here, the researcher uses financial ratios in the form of Solvency Ratios represented by the Debt Assets Ratio, Debt Equity Ratio, and Long Term Debt to Equity Ratio, besides that they also use Profitability Ratios which are represented by Gross Profit Margin, Net Profit Margin, Return on Investment and Return on Equity. The result of this research is that PT. Retabtama when viewed from the Solvency Ratio shows that the company is in a very good condition where the company is able to manage its debt. Besides that, it is also seen from the Profitability Ratio that the company is less effective in utilizing assets and managing capital so the company has decreased in terms of income and profit.
МУНАВВАР ҚОРИ – БУЮК ҲУҚУҚШУНОС ВА МИЛЛАТ ФИДОЙИСИ
Authors: Мавлуда Э.
Published: April 2023

Мақолада буюк маърифатпарвар жадид Мунаввар қори Абдурашидхоновнинг ҳуқуқий қарашлари ва элу юрт равнақи йўлидаги беқиёс хизматлари ёритилган.

This article highlights the great thinker Munavvar qori Abdurashidkhanov’s legal views and his invaluable contribution to the development of the country.

В статье исследуются правовые воззрения узбекского просветителя и одного из лидеров национальнопросветительского движения джадидов Мунаввара кори Абдурашидханова.
PROTECTION OF THE RIGHTS AND LEGITIMATE INTERESTS OF VICTIMS IN THE CONSTITUTION OF NEW UZBEKISTAN
Authors: Dilnoza T.
Published: April 2023

The article analyzes the social and legal necessity of protecting the rights and interests of victims in constitutional provisions. It expresses opinions on proposals aimed at improving the mechanism for compensating the harm caused to a victim as a result of the crime, protecting the rights and interests of the victim.

Мақолада жабрланувчининг ҳуқуқ ва манфаатларини ҳимоя қилиш конституцион нормаларда ифодаланишининг ижтимоий-ҳуқуқий зарурати таҳлил қилинган. Шунингдек, жабрланувчига жиноят туфайли етказилган зарарни қоплаш, унинг ҳуқуқ ва манфаатларини муҳофаза қилиш механизмини такомиллаштиришга қаратилган таклифлар билдирилган.

В статье анализируется социально-правовая необходимость выражения прав и интересов потерпевшего в конституционных положениях. Автор вносит предложения, направленные на совершенствование механизма возмещения вреда, причиненного потерпевшему в результате преступления, защиту прав и интересов потерпевшего.
ЕВРОПА ИТТИФОҚИ ТАШҚИ СИЁСАТИНИНГ ЎЗИГА ХОС ХУСУСИЯТЛАРИ: ИТТИФОҚНИНГ “НОРМАТИВ ҚУДРАТИ”
Authors: Ҳайдарали Ю.
Published: April 2023

Ушбу мақолада Европа Иттифоқи ташқи сиёсатининг ҳуқуқий асослари, институцио-нал тизими ва ўзига хос хусусиятлари таҳлил қилинган. Муаллиф томонидан Европа Иттифоқи “нор-матив қудрати”нинг асосий моҳияти, воситалари ҳамда намоён бўлиш шакллари тадқиқ этилган. Му-аллифнинг фикрига кўра, Европа Иттифоқининг “норматив қудрати” унинг “юмшоқ қудрати”ни тўлди-ради ҳамда халқаро муносабатлар тизими ва жаҳон сиёсатидаги мавқеини мустаҳкамлашга хизмат қилади.

This article analyzes the legal framework, institutional system and specific features of the EU foreign policy. The author explores the essence, means and manifestations of the “normative power” of the European Union. According to the author, the “normative power” of the European Union complements its “soft power” and serves to strengthen its position in the system of international relations and world politics.

В статье анализируются правовая база, институциональная система и особенности внешней политики Европейского Союза. Автор исследует сущность, средства и проявления «норма-тивной власти» ЕС. По мнению автора, «нормативная сила» Евросоюза дополняет его «мягкую силу» и служит укреплению его позиций в системе международных отношений и мировой политики.
THE ROLE AND STATUS OF HUMAN RIGHTS EDUCATION IN THE PROTECTION OF HUMAN RIGHTS AND FREEDOMS BY THE ORGANIZATION OF ISLAMIC COOPERATION: MODERN TRENDS
Authors: Oybek A.
Published: April 2023

The article analyzes the place, condition and development of Human Rights education in the member states of the Organization of Islamic Cooperation, as well as the tendency to bring its statutes, declarations and all documents of the organization in line with generally recognized international norms and standards in the field of Human Rights

Мақолада Ислом ҳамкорлик ташкилотига аъзо давлатларда инсон ҳуқуқлари соҳасидаги таълимнинг ўрни, ҳолати ва ривожланиши, шунингдек ташкилот низомлари, декларациялари ҳамда бошқа барча ҳужжатларини инсон ҳуқуқлари соҳасидаги умумэътироф этилган халқаро ҳуқуқий норма ва мезонларга мувофиқлаштириш тенденцияси таҳлил қилинган.

В статье анализируются место, состояние и развитие образования в области прав человека в государствах-членах Организации исламского сотрудничества, а также тенденция к приведению ее уставов, деклараций и всех документов организации в соответствие с общепризнанными международными нормами и стандартами в области прав человека.
SC Claudianum and Levitas Animi – a Gender Issue?
Authors: Erdődy János
Published: April 2023

During the reign of Emperor Claudius, a senatusconsultum from 52 AD contained provision concerning free women sustaining a relationship with the slave of another. In accordance with these provisions should she fail to abandon the relationship after the denouncement of the slave’s master, will become the slave of the master denouncing her deed. The senatusconsultum also contains rules regarding the status of the children born from such a relationship. Some scholars tend to label this decree of the Roman Senate a “gender issue” despite the obvious anachronism of the statement. This paper aims at unfolding the sustainability of such a label. In the scope of this endeavour the common and generally known phrases, levitas animi and infi rmitas sexus are also examined. Connected to tutela feminarum, the locutions levitas animi and infi rmitas sexus turn out to contribute to a common, but mistaken opinion how women were regarded in ancient Roman society. Placed properly amongst primary sources, it turns out that they refl ect an attitude stemming from Greek philosophy, and therefore not common throughout the entire history of Rome. As for the approach of male and female roles in Roman society, mores maiorum plays an undoubtedly important part in determining the actual content of social customs. There’s also a strong endeavour to protect women in certain situations, and this is where tutela mulierum is supposedly originates from. Secondary literature does not rank SC Claudianum among “gender issues”. In addition, the term “gender issue” as such covers a modern concept, and therefore anachronistic in Roman law research, as a consequence its use is at least doubtful.
PENGARUH BANTUAN PEMERINTAH DAN KEMAMPUAN USAHA TERHADAP KINERJA KEUANGAN UMKM KOTA JAYAPURA
Authors: Yusuf Ghulam Muhamad
Published: April 2023

Usaha kecil dan menengah sebagai salah satu komponen dalam industry di provinsi papua, mempunyai peran yang sangat penting dalam perekonomian Regional, penyerepan anggaran kerja, pemerataan hasil-hasil pembangunan, dan penanggulangan kemiskinan. Oleh karena Itu, pemerintah telah memiliki pilar-pilar kebijakan yang strategis yang diimplementasikan melalui berbagai kebijakan/program dan kegiatan tahunan untuk mendukung pengembangan dan penguatan UKM di provinsi Papua. Usaha mikro dan kecil (UKM) umumnya memiliki keunggulan dalam bidang yang memanfaatkan sumberdaya alam dan padat karya, misalnya pertanian tanaman pangan, perkebunan, peternakan, perikanan, perdagangan dan restoran. Teori yang digunakan teori bantuan pemerintah dengan indikator indicator yang diapaki adalah : program pelatihan dan pendampingan, akses permodalan, dan bantuan akses pasar. Teori selanjutnya dalah teori kemampuan usaha dengan indicator- indicator yang digunakan adalah kemampuan UKM dalam hal produksi, pemsaran, keuangan dan kemampuan 4P. (Product, Price Place and Promotion). Dan teori berikutnya adalah kinerja keuangan UKM dengan indicator informasi akuntansi manajemen, informasi akuntansi keuangan (laba sebelum pajak, timgkat pengambilan pinjaman dll.) dan pertumbuhan penjualan.Metode penelitian kuantitatif, menggunakan statistic regresi dengan bantuan software SPSS. Versi 20. Populasi dalam penelitian ini sebanyak 140 orang yang keseluruhan adalah para pelaku UKM di Kota Jayapura. Hasil penelitian menjelaskan secara bersama sama variable bantuan pemerintah dan kemampuan usaha dapat memberikan pengaruh positif terhadap peningkatan kinerja keuangan UKMKM di Kota Jayapura. Artinya jika kedua variable tersebut dapat dilaksanakan dan berjalan dengan baik maka mampu memberikan semangat kerja bagi para pelaku UKM sehingga dapat meningkatkan kinerja keuangan semakin lebih baik kedepannya. Secara parsial baik variable bantuan pemerinah dan kempuan usaha menunjukan pengaruh yang signifikan terhadap kinerja keuangan UMKM di kota jayapura. Hal ini mengindikasikan bahwa bantuan pemerintah yang tinggi, kemampuan usaha yang baik akan dapat memberikan suatu dorongan bagi para pelaku UMKM untuk melakukan tugas dan tanggung jawab dengan baik sehingga dapat menghasilkan kinerja keuangan yang baik pula. Variable yang dominan berpengaruh terhadap kinerja keuangan UMKM adalah variable bantuan pemerintah, karena dengan bantuan pemerintah yang baik maka dapat memberikan semangat kerja bagi pengusaha UMKM sehingga dapat melaksanakan kinerja dengan baik pula.
Morfología del proceso coracoideo con resonancia magnética nuclear para suplir defectos óseos glenoideos anterior
Authors: Orozco Luis Soto
Published: April 2023

El objetivo de este trabajo es determinar la morfología del proceso coracoideo con resonancia magnética nuclear para suplir los defectos óseos glenoideos anteriores. Es un estudio descriptivo, prospectivo, no experimental y transversal. Se incluyeron pacientes de ambos sexos, con edad igual o mayor a 18 años, seleccionados en la Unidad de Hombro del Hospital Ortopédico Infantil, a los cuales se les aplicó resonancia magnética nuclear de hombro para conocer la morfología y medida de la coracoides. Se incluyeron 164 pacientes. 86(52,43%) de sexo femenino, la edad media fue 49,4 años. La morfología más frecuente de la coracoides fueron el Tipo II 74(45,1%). La medición de la coracoides en promedio fue longitud 26,4mm, altura 9,82mm, ancho 8,31mm en la población en general con una mediana de longitud de 26,83mm, altura 9,35mm y ancho 8,39mm. El Tipo I: longitud 26,00mm, alto 9,59mm, ancho 8,37mm; Tipo II: longitud 26,42mm, altura 9,89mm, ancho 8,42mm; Tipo III: longitud 26,88mm, alto 10,05mm, ancho 7,98mm. En el sexo masculino el promedio de longitud: 27,01mm, alto: 10,71mm, ancho: 8,93mm. en el sexo femenino en promedio longitud: 25,98mm, alto: 9,20mm, ancho: 7,88mm. La técnica de Latarjet posición arco convencional y congruente en su diámetro ancho aporta el Tipo I: 8,37mm y congruente 9,59mm (-1,22mm), el tipo II: 8,42mm y congruente 9,89mm (-1,47mm) y el tipo III: 7,98mm y congruente 10,05mm (-2,01mm). En el sexo femenino la apófisis coracoides tiene un menor diámetro en comparación con el sexo masculino.
Tratamiento de la disociación espinopélvica en fracturas sacras multiplanares. Reporte de Caso
Authors: Roa Z. Adrien , Mata Mariangela , Sepúlveda Ingrid
Published: April 2023

Las fracturas sacras multiplanares se caracterizan por la combinación de líneas de fractura horizontales y verticales bilaterales, lo que da lugar a patrones complejos de fractura. Debido a la complejidad y a la baja frecuencia de presentación de estas lesiones en la literatura. El objetivo de este trabajo es evaluar las estrategias del tratamiento quirúrgico en la Disociación Espinopélvica de las fracturas sacras multiplanares a través de la osteosíntesis triangular con Sistema Espinopélvico y presentar el caso de una paciente femenino de 40 años, quien posterior a traumatismo de alta energía presentó una fractura sacra multiplanar. Se concluye que las fracturas sacras multiplanares, con Disociación Espinopélvica asociadas o no a lesión neurológica es a través de la Osteosíntesis Triangular con Sistema Espinopélvico más fijación con tornillos iliosacros, ya que este procedimiento simula la acción de los ligamentos que estabilizan verticalmente al anillo pélvico posterior. En este caso se logró una adecuada estabilidad del anillo pélvico, permitiendo a la paciente movilidad precoz, con el inicio de medicina física y rehabilitación a las 24 horas del postoperatorio, la realización de ejercicios isométricos e isotónicos. Se evidencia una mejoría de la sintomatología neurológica. Con una evolución satisfactoria a las 6 semanas, donde no se observó compromiso neurológico de las raíces del plexo-sacro.
The Effectiveness of Telerehabilitation for Post Stroke Patients
Authors: Glenis Gabrielle , Setiawan Regina Caecilia , Ulianna Tambunan Tresia Fransiska
Published: April 2023

Stroke rehabilitation is an essential component of post-stroke care and is more effective if started sooner. Stroke rehabilitation therapy aims to improve motor function, psychological well-being, cognitively, emotionally, and in terms of social well-being. Telerehabilitation allows communication between medical staff and patients and can be a suitable alternative to usual rehabilitation care in poststroke patients. This method may have potential implications for patients, especially in remote or underserved areas. Future trials are needed on telerehabilitation’s feasibility, efficacy, and cost-effectiveness in other low and middle-income countries where the stroke burden is burgeoning.

Rehabilitasi stroke merupakan komponen penting dalam tatalaksana pasca-stroke dan lebih efektif untuk dimulai lebih awal. Tujuan terapi rehabilitasi stroke adalah untuk meningkatkan fungsi motorik, kognitif, emosional, kesejahteraan psikologis dan sosial. Telerehabilitasi memungkinkan komunikasi antara staf medis dan pasien dan dapat sebagai alternatif yang sesuai untuk perawatan rehabilitasi biasa pada pasien pasca-stroke. Metode ini mungkin memiliki implikasi potensial bagi pasien, terutama di daerah terpencil atau kurang terlayani. Penelitian masih diperlukan untuk kelayakan, kemanjuran, dan keefektifan biaya telerehabilitasi di negara berpenghasilan rendah dan menengah dengan beban stroke meningkat.
Trombosis pada Pasien COVID-19
Authors: Tan Christine
Published: April 2023

Penyakit Coronavirus 2019 (COVID-19) memiliki spektrum klinis yang luas. Salah satu gejala berat penyakit ini dan menunjukkan prognosis buruk adalah trombosis. Risiko tinggi trombosis pada COVID-19 ditunjukkan dari peningkatan D-dimer yang merupakan perubahan paling signifikan parameter koagulasi, yang menandakan produksi trombin dan aktivasi fibrinolisis. Namun, D-dimer adalah reaktan fase akut nonspesifik dan dapat meningkat karena penyebab dan inflamasi lain. Identifikasi risiko dini dan tanda trombosis pada pasien COVID-19 dapat mencegah kejadian trombotik dan gagal organ lainnya, memandu tenaga kesehatan pada strategi intervensi awal, dan fokus pada kelompok pasien yang berisiko prognosis buruk.

Coronavirus disease 2019 (COVID-19) has a broad clinical spectrum. Thrombosis may herald severe symptom and indicates a poor prognosis. Risk of thrombosis in COVID-19 is indicated by increased D-dimer, which is the most significant change in coagulation parameters, indicating thrombin production and fibrinolysis activation. However, D-dimers are nonspecific acute-phase reactants and may increase due to other causes and inflammation. Identifying early risks and signs of thrombosis in COVID-19 patients to prevent thrombotic events and other organ failure, may guide health professionals on early intervention strategies, and to focus on groups of patients at risk of poor prognosis.
Antidiabetik Oral Kombinasi Penghambat DPP-4 dan Penghambat SGLT-2
Authors: Lukito Johan Indra
Published: April 2023

Dalam tatalaksana diabetes melitus tipe 2, terapi kombinasi dua obat antidiabetik disarankan jika dengan monoterapi gagal mencapai target kontrol glikemik. Pemilihan jenis obat antidiabetik tergantung kondisi pasien dan profil obat. Kombinasi obat antidiabetik oral golongan penghambat DPP-4 (dipeptidyl peptidase-4) dan penghambat SGLT-2 (sodium-glucose cotransporter type 2) dapat menjadi salah satu pilihan.

Combination of two antidiabetic drugs is recommended in the management of type 2 diabetes mellitus if monotherapy fails to achieve glycemic control targets. Choice of antidiabetic drugs depends on the patient's condition and drugs’ profile. Combination of oral antidiabetic drugs DPP-4 (dipeptidyl peptidase-4) class and SGLT-2 (sodium-glucose cotransporter type 2) inhibitors can be an option.
Hubungan Indeks Massa Tubuh dan Usia Menarche dengan Pola Siklus Menstruasi Siswi SMA di Pontianak
Authors: Monica Meilany Gultom  , Agus Fitriangga  , Ilmiawan Muhammad In’am
Published: April 2023

Latar Belakang: Pola siklus menstruasi disebut normal apabila tidak kurang dari 21 hari serta tidak melebihi 35 hari. Tujuan: Diketahuinya hubungan antara indeks massa tubuh dan usia menarche terhadap panjangnya siklus menstruasi pada siswi SMA di Pontianak. Metode: Penelitian analitik observasional cross-sectional. Variabel bebas penelitian adalah indeks massa tubuh dan usia menarche, variabel terikat adalah panjangnya siklus menstruasi. Total sampel penelitian 40 orang. Hasil: Terdapat hubungan antara indeks massa tubuh dan panjangnya siklus menstruasi (uji Fisher’s Exactp = 0,02). Tidak terdapat hubungan antara usia menarche dan panjangnya siklus menstruasi (uji Chi-Square p = 0,305). Simpulan: Indeks massa tubuh berhubungan dengan panjangnya siklus menstruasi siswi.

Background: Menstrual cycle pattern is normal if not less than 21 days and not exceed 35 days. Objective: To evaluate the relationship between bodies mass index and age of menarche on the menstrual cycle among female senior high school students in Pontianak. Method: Observational analytic study with cross-sectional design. The independent variables were body mass index and age of menarche, the dependent variable was menstrual cycle. Total sample were 40 students. Results: There is a relation between body mass index and the menstrual cycle (Fisher’s Exact test p = 0,02). No relation between age of menarche and the menstrual cycle (Chi-Square test p = 0,305). Conclusion: Body mass index has a relation toward the menstrual cycle among female senior high school students in Pontianak.
Tatalaksana Pasca-Henti Jantung
Authors: Willim Herick Alvenus , Ketaren Infan , Supit Alice Inda
Published: April 2023

Sindrom pasca-henti jantung merupakan keadaan kompleks dan kritis dengan mortalitas tinggi. Tatalaksana pasca-henti jantung membutuhkan pendekatan multidisiplin meliputi stabilisasi status kardiopulmoner, penanganan penyebab, strategi neuroproteksi dini, dan pencegahan berulangnya henti jantung. Pendekatan multimodal diperlukan untuk prediksi keluaran neurologis.

Post-cardiac arrest syndrome is complex and critical condition associated with high mortality. Post-cardiac arrest management needs multidisciplinary approach including stabilization of cardiopulmonary status, managing the underlying cause, early neuroprotective strategy, and prevention of recurrent cardiac arrest. Multimodal approach is needed to predict neurological outcome.
Diagnosis dan Tatalaksana Paroxysmal Nocturnal Hemoglobinuria
Authors: Siauw Cecile
Published: April 2023

Paroxysmal nocturnal hemoglobinuria (PNH) merupakan kelainan sel hematopoesis didapat yang menyebabkan hemolisis intravaskular dan berisiko tinggi trombosis. PNH terdiri dari PNH klasik, PNH terkait kegagalan sumsum tulang, dan PNH subklinis. Diagnosis PNH dengan flow cytometry (FCM). Terapi PNH saat ini menggunakan eculizumab, ravulizumab, dan transplantasi sel punca alogenik.

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder of hematopoietic stem cell causing intravascular hemolysis and high risk of thrombosis. It can be differentiated into: classical PNH, PNH associated with bone marrow failure, and subclinical PNH. Diagnosis is made by flow cytometry. PNH is treated with eculizumab, ravulizumab, and allogenic stem cell transplantation.
Hubungan antara Konstipasi dengan Akne Vulgaris dan Derajat Keparahannya pada Mahasiswa Kedokteran di Jakarta
Authors: Renate Anastasia Rena , Tanjung Julia Rahadian
Published: April 2023

Latar Belakang: Teori koneksi organ otak-usus-kulit menunjukkan hubungan erat antara kondisi usus dan kondisi dermatologis. Keadaan konstipasi dapat menyebabkan produk sekretori usus menuju peredaran sistemik yang dapat meningkatkan inflamasi organ kulit, sehingga rentan terhadap akne vulgaris. Metode: Penelitian cross-sectional pada 100 mahasiswa laki-laki usia 17-22 tahun dengan metode stratified random sampling. Penilaian konstipasi menggunakan kuesioner gejala konstipasi berdasarkan Kriteria Rome III dan penilaian derajat keparahan akne vulgaris menggunakan Evaluator Global Severity Score (EGSS). Hubungan antara variabel independen dan dependen diuji menggunakan Chi-Square dan Fisher-exact. Hasil: Didapatkan 100 responden, usia terbanyak yang mengalami akne vulgaris adalah 19 tahun dan usia terbanyak yang mengalami konstipasi adalah 20 tahun.Terdapat hubungan bermakna antara konstipasi dan akne vulgaris (p=0,012). Berdasarkan derajat keparahannya, tidak terdapat hubungan antara konstipasi dan akne vulgaris derajat ringan (p=0,973) namun terdapat hubungan antara konstipasi dan akne vulgaris derajat sedang – berat (p=0,048). Simpulan: Penelitian ini menunjukkan hubungan bermakna antara konstipasi dan akne vulgaris.
 
Background: The theory of brain-intestinal-skin connections shows a relationship between intestinal and dermatological conditions. Constipation stimulate the intestine secretory products towards systemic circulation and increase inflammation of the skin, acne vulgaris. Method: This cross-sectional study involved 100 male students aged 17-22 years with stratified random sampling method. Constipation assessment used constipation questionnaire based on Rome III Criteria and assessment for severity of acne vulgaris used Evaluator Global Severity Score (EGSS). The relationship between independent and dependent variables was tested using Chi-Square and Fisher-exact. Result: Majority respondents who have acne vulgaris is 19 year-old and constipation is mostly found in 20 year-old. There is significant relationship between constipation and acne vulgaris (p=0.012). No significant relationship between constipation and mild acne vulgaris (p=0.973) but there is a significant relationship between constipation and moderate to severe acne vulgaris (p=0.048). Conclusion: This study shows possible role of digestive organ health in acne vulgaris incidence.