bluuebunny/crossref_metadata_2025 huggingface dataset:
PEMBERDAYAAN UMKM KAUM DISABILITAS BINAAN YPII DI PROVINSI BALI
Authors: Br Sitepu Sri Nathasya , Sienatra Krismi Budi , Teguh Monika
Published: July 2024

Pemberdayaan dan pendampingan wirausaha UMKM kaum disabilitas yang merupakan binaan Yayasan Plan Internasional Indonesia (YPII) bertujuan untuk mempersiapkan wirausaha muda khususnya kaum disabilitas meningkatkan taraf hidup. Kegiatan pendampingan ini dilakukan dengan dua metode secara daring dan onsite. Pendampingan daring yang dilakukan meliputi tentang membangun mindset entrepreneurial, motivasi diri, pitching komunikasi. Pendampingan onsite dilakukan dengan melakukan analisis situasi, mentoring dan masukan perbaikan, penerapan story telling. Hasil dari pendampingan ini memberikan berbagai manfaat baik non-ekonomi dan ekonomi. Manfaat non-ekonomi menghasilkan kepercayaan diri dari peserta dimana mereka yakin dapat berkontribusi seperti orang nomal lainnya. Manfaat secara ekonomi menghasilkan adanya penghasilan dari angkatan kerja kaum disabilitas dan munculnya berbagai inovasi dari produk yang dihasilkan kaum disabilitas.
Permainan Ular Tangga sebagai Media Sosialisasi Kebiasaan Hidup Sehat di SDN Jatinangor Kabupaten Sumedang
Authors: Dewi Retasari , Dida Susanne , Lusiana Elnovani , Yuliani Rostika
Published: July 2024

Pandemi Covid 19 sedikit banyak mengubah cara pandang dan cara masyarakat mengelola kesehatan. Beberapa protokol kesehatan tetap dipertahankan sebagai bagian dari upaya pencegahan penyakit. Kebiasaan sehat ini harus di sosialisasikan juga pada anak-anak sebagai kelompok yang rentan terkena infeksi pernapasan. Salah satu cara menyosialisasikan pentingnya menerapkan kebiasaan hidup sehat kepada anak-anak dilakukan melalui permainan. Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah untuk menyosialisasikan kebiasaan hidup sehat dengan memanfaatkan permainan ular tangga sebagai media sosialisasi. Kegiatan ini dilakukan di SDN Jatinangor Kabupaten Sumedang. Metode yang digunakan dalam kegiatan ini adalah metode permainan interaktif dan hasilnya diukur dengan menggunakan pre test dan post test. Hasil penelitian ini menunjukkan bahwa terdapat perbedaan yang signifikan antara nilai pre test dan post test pada sampel. Hal ini menunjukkan bahwa penggunaan permainan ular tangga efektif dalam meningkatkan pengetahuan siswa sekolah dasar di SDN Jatinangor Kabupaten Sumedang tentang kebiasaan hidup sehat.
PENGELOLAAN KEUANGAN DI AGROWISATA PALOH NAGA MELALUI PENDEKATAN COMMUNITY BASED PARTICIPATORY ACTION RESEARCH
Authors: Irawan Muhammad Dedi , Syafina Laylan , Putri Raissa Amanda , Siregar Yustria Handika
Published: July 2024

Agrowisata Paloh Naga, destinasi wisata di Desa Denai Lama, masih menggunakan pencatatan keuangan manual, yang meningkatkan risiko kesalahan perhitungan. Tujuan penelitian ini adalah untuk meningkatkan transparansi laporan keuangan dan memudahkan pengelola Agrowisata Paloh Naga dalam menggunakan Tempu sebagai alat pembayaran. Metodologi yang digunakan adalah Community Based Participatory Action Research (CBPAR), melibatkan mitra seperti BumDes Sastro 3-16, Unity Academy, dan Lembaga Penelitian dan Publikasi Ali. Hasil menunjukkan bahwa pendampingan pengelolaan keuangan di Agrowisata Paloh Naga membawa manfaat signifikan, termasuk peningkatan pemahaman melalui pelatihan, penerapan aplikasi laporan keuangan, kemudahan mencetak laporan dengan printer kasir, dan pembuatan video dokumenter kegiatan
KOLABORASI DALAM PELATIHAN PENULISAN KARYA ILMIAH MAHASISWA MENGGUNAKAN MEDIA DARING
Authors: Febriyanti Doris , Zubaidah Siti , Yuslaini Nina
Published: July 2024

This training activity aims to optimize students' ability to write and publish scientific papers through coordinated online training. The training, which was held on Saturday, May 25, 2024, involved 150 students from various universities in Indonesia, including Indo Global Mandiri University, STIA Bala Putra Dewa, Universitas Terbuka, Sriwijaya University, UIN Walisongo University Semarang, Jakarta State University, Palembang Ministry of Health Polytechnic, and STIE Aprin Palembang. The method of the activity is planned by identifying problems, carried out online through WhatsApp Groups and Zoom Meetings, including three sessions of delivering interesting material about scientific publications and writing. Each session began with an opening by the MC, prayer reading, and singing the Indonesia Raya song, followed by material presentations by three speakers. This training is designed to overcome students' limited knowledge in scientific writing and utilize digital technologies, including Artificial Intelligence, to improve the quality and effectiveness of their scientific work. Through this program, it is hoped that students can better understand the process of scientific writing and publication, so that they can produce works that are of higher quality and ready to be published.
Distinguishing Benign and Malignant Ovarian Tumors Preoperatively
Authors: Adhipurnawan Winarno Gatot Nyarumenteng
Published: July 2024

Ovarian cancer ranks as the fifth leading cause of cancer-related mortality among women globally. In 2020, there were approximately 314,000 reported cases of new ovarian cancer patients, resulting in an estimated 207,000 deaths.1 The highest incidence rates were observed in non-Hispanic white women, with 12.0 cases per 100,000 individuals, followed by Hispanics (10.3 per 100,000), non-Hispanic blacks (9.4 per 100,000), and Asian/Pacific Islander women (9.2 per 100,000). Disparities in access to healthcare services and treatment modalities contribute to varied mortality patterns, with the highest rates recorded among African populations. In Indonesia, ovarian cancer ranks as the third most prevalent cancer, comprising 7.84% of total cancers diagnosed in women.1 The heightened mortality rate observed in ovarian cancer can be ascribed to several factors including asymptomatic tumor growth, delayed manifestation of symptoms, and inadequate screening methods, ultimately resulting in diagnoses at advanced stages. Consequently, ovarian cancer is frequently described as a “silent killer”.2 To address diagnostic delays and reduce mortality rates associated with ovarian cancer, early detection and differentiation between benign and malignant ovarian tumors are crucial. This requires a comprehensive assessment comprising patient history, physical examination, and supporting investigation.
Overview of Midwives’ Knowledge of Postpartum Bleeding to Reduce Maternal Mortality Rate In Working Area at Pelabuhan Ratu Hospital
Authors: Apriliyani Sinta Nur , Tjahja Raden
Published: July 2024

Introduction:The Maternal Mortality Rate indicator shows the level of risk of maternal death during pregnancy, childbirth, and the postpartum period per 100,000 live births in a given area over a certain period. According to the district health profile report, Maternal deaths in 2023 reached 792 cases or 96.89 per 100,000 live births, an increase of 114 cases compared to 2022 which recorded 678 cases. In 2022 Sukabumi district common causes of maternal death are hemorrhage 14 case and 7 case in 2023Methods:Study used a descriptive approach with a cross-sectional design involving 74 midwives. The sampling technique was random sampling. Data were obtained through the use of questionnaires that focused on the variable of knowledge about postpartum hemorrhage. Data analysis was performed using the univariate analysis method.Results:It was found of 74 midwives in the working arae of Pelabuhan Ratu Hospital, the majority were 31-35 years old (43.2%), had D3 Midwifery educational background (59.5%), and had 11-15 years of work experience (33.8%). In addition, 77% not attended PPGDON training. Most midwives (55.4%) had a good understanding of postpartum hemorrhage. Conclusion:The majority of midwives in working area at Pelabuhan Ratu Hospital have good knowledge about postpartum hemorrhage.Gambaran Pengetahuan Bidan tentang Perdarahan Pascapersalinan untuk Menurunkan Angka Kematian Ibu di Wilayah Kerja RSUD Pelabuhan RatuAbstrakPendahuluan: Indikator Angka Kematian Ibu menunjukkan tingkat risiko kematian ibu pada masa kehamilan, persalinan, dan masa nifas per 100.000 kelahiran hidup di suatu wilayah selama periode tertentu. Berdasarkan laporan profil kesehatan daerah, kematian ibu pada tahun 2023 mencapai 792 kasus atau 96,89 per 100.000 kelahiran hidup, Hal ini meningkat 114 kasus dibandingkan tahun 2022 yang tercatat 678 kasus. Di Kabupaten Sukabumi tahun 2022 penyebab kematian ibu terbanyak adalah perdarahan 14 kasus dan tahun 2023 menjadi 7 kasus.Metode: Penelitian menggunakan pendekatan deskriptif dengan desain cross-sectional yang melibatkan 74 bidan. Teknik pengambilan sampelnya adalah random sampling. Data diperoleh melalui penggunaan kuesioner yang berfokus pada variabel pengetahuan tentang perdarahan postpartum. Analisis data dilakukan dengan menggunakan metode analisis univariat.Hasil: Ditemukan dari 74 bidan di wilayah kerja RS Pelabuhan Ratu, mayoritas berusia 31 – 35 (43,2%), berlatar belakang pendidikan D-3 Kebidanan (59,5%), dan memiliki pengalaman kerja 11 – 15 (33,8%). Selain itu, 77% tidak mengikuti pelatihan PPGDON. Sebagian besar bidan (55,4%) memiliki pemahaman yang baik mengenai perdarahan pascapersalinan. Kesimpulan: Mayoritas bidan di wilayah kerja RS Pelabuhan Ratu memiliki pengetahuan yang baik tentang perdarahan postpartum.Kata kunci: Bidan, Perdarahan Pascapersalinan, Pelabuhan Ratu
The Analysis of Premature Rupture of Membrane Outcomes: Comparison Between 34-36 Weeks and Term Gestation
Authors: Yordian Kendry Savira , Pribadi Adhi , Syam Hanom Husni , Nugrahani Annisa Dewi , Handono Budi , Susiarno Hadi , Suardi Dodi
Published: July 2024

Introduction: This study analysed the maternal and neonatal outcomes in premature rupture of membrane at 34-36 weeks of gestation compared to term gestation to provide an overview of the current protocol’s efficacy which is currently widely varied. Method: This was a cross-sectional study using a simple random sampling technique. The subject of this study consisted of a total of 450 pregnant women diagnosed with PPROM at 34-36 weeks and term gestation during the period January 2019-December 2021. P<0.05 was considered statistically significant. Results: That women with premature rupture of membrane (PROM) at term gestation had a higher risk of 1.13 times (OR= 1.13, CI 95%) for neonatal asphyxia, 1.34 times for early neonatal death (OR= 1.34, CI 95%), and 4.03 times for developing clinical chorioamnionitis (OR= 4.03, CI 95%) compared to the 34-36 weeks of gestation group. There was no statistically significant difference between gestational age and the incidence of early neonatal death (P= 0.70). There were no maternal deaths in this study. Conclusion: the management protocol applied for both groups had the same efficacy. The incidence of clinical chorioamnionitis was higher in the term gestation group, which may be associated with risk factors such as COVID-19 and hepatitis B.Analisis Hasil Ketuban Pecah Dini: Perbandingan Antara Usia Kehamilan 34-36 Minggu dan Masa KehamilanAbstrakPendahuluan: Penelitian ini menganalisis hasil maternal dan neonatal pada ketuban pecah dini pada usia kehamilan 34 - 36 minggu dibandingkan dengan kehamilan jangka panjang untuk memberikan gambaran tentang kemanjuran protokol saat ini yang sangat bervariasi. Metode: Penelitian ini adalah studi cross-sectional menggunakan teknik simple random sampling. Subjek penelitian ini terdiri atas total 450 wanita hamil yang didiagnosis dengan PROM pada 34 - 36 minggu dan kehamilan jangka panjang selama periode Januari 2019 - Desember 2021. P<0,05 dianggap signifikan secara statistik. Hasil: hasil analisis menunjukan bahwa wanita dengan ketuban pecah dini pada usia kehamilan memiliki risiko lebih tinggi 1,13 kali (OR= 1,13, CI 95%) untuk asfiksia neonatal, 1,34 kali untuk kematian neonatal dini (OR= 1,34, CI 95%), dan 4,03 kali untuk mengembangkan chorioamnionitis klinis (OR= 4,03, CI 95%) dibandingkan dengan kelompok kehamilan 34 - 36 minggu. Tidak ada perbedaan yang signifikan secara statistik antara usia kehamilan dan kejadian kematian neonatal dini (P = 0,70). Tidak ada kematian ibu dalam penelitian ini. Kesimpulan: Protokol manajemen yang diterapkan untuk kedua kelompok memiliki kemanjuran yang sama. Insiden chorioamnionitis klinis lebih tinggi pada kelompok kehamilan, yang mungkin terkait dengan faktor risiko seperti COVID-19 dan hepatitis B.Kata kunci: Ketuban pecah dini, asfiksia, kematian neonatal
Neonatal Outcome in Relation to Cardiotocography Interpretation During Pregnancy
Authors: Megantoro Izzati Faustina , Pribadi Adhi , Nurdiawan Windi , Hidayat Dini , Ritonga Mulyanusa
Published: July 2024

Introduction: The aim of this study is to evaluate the interrelation between neonatal outcome (neonatal asphyxia status) and cardiotocography interpretation during pregnancy.Methods: This is an observational analytical study employing a cross-sectional approach involving patients delivering at Hasan Sadikin General Hospital in 2023. The inclusion criteria were patients who gave birth with cardiotocography interpretation and neonatal outcome recording at 32-37 weeks of gestation. The exclusion criteria were fetal with congenital anomalies and multiple pregnancy. This study utilized secondary data from patient case notes. This study employed non-probability consecutive sampling. Descriptive and analytical statistics were performed.Result: The result of this study indicates abnormal cardiotocography patterns are significantly associated with higher incidences of asphyxia (p=0.0001). No significant difference was found between incidence of asphyxia with the type of delivery and birth weight. There was also no significant difference between Cardiotocography category II and III based on the maternal and neonatal factors.Conclusion: This study concluded that the significant relationship between CTG results, and neonatal asphyxia underscores the importance of CTG monitoring in predicting and managing fetal distress.Luaran Neonatus berdasarkan Pemeriksaan Kardiotokografi pada KehamilanAbstrakPendahuluan: Tujuan penelitian ini adalah untuk mengevaluasi hubungan antara hasil neonatal (status asfiksia neonatal) dan interpretasi kardiotokografi selama kehamilan.Metode: Metode penelitian ini adalah analitik observasional dengan pendekatan cross-sectional yang melibatkan pasien yang melahirkan di Rumah Sakit Umum Hasan Sadikin pada tahun 2023. Kriteria inklusi adalah pasien yang melahirkan dengan interpretasi kardiotokografi dan pencatatan hasil neonatal pada usia kehamilan 32 – 37 minggu. Kriteria eksklusi adalah janin dengan anomali kongenital dan kehamilan ganda. Penelitian ini menggunakan data sekunder dari catatan kasus pasien. Penelitian ini menggunakan metode sampling konsekutif non-probabilitas. Statistik deskriptif dan analitik dilakukan.Hasil: Hasil penelitian ini menunjukkan bahwa pola kardiotokografi abnormal secara signifikan terkait dengan insiden asfiksia yang lebih tinggi (p=0.0001). Tidak ditemukan perbedaan signifikan antara insiden asfiksia dengan jenis persalinan dan berat lahir. Tidak ada perbedaan signifikan antara kategori Kardiotokografi II dan III berdasarkan faktor maternal dan neonatal.Kesimpulan: Penelitian ini menyimpulkan bahwa hubungan signifikan antara hasil CTG dan asfiksia neonatal menekankan pentingnya pemantauan CTG dalam memprediksi dan mengelola distress janin.Kata kunci: Kardiotokografi, Neonatal, Distress janin, APGAR
Idiopathic macular hole – literature review.
Authors: Niedzielska-Krycia Agata , Krycia Karol , Dereń-Szumełda Joanna , Górska Aleksandra , Sirek Sebastian , Wyględowska-Promieńska Dorota
Published: July 2024

Full-thickness idiopathic macular hole (MH) is a common cause of visual loss, affecting 3 per 1000 people. It usually affects females in their sixth to eighth decades of life. Best Visual Acuity decreases to less than 0.5. A typical MH’s symptom is the pincushion metamorphopsia, where the shape of an observed object is enrolled inwards and lines are bowed towards the center, in the direction of the fixation point. Over the years many theories of MH formation have been revealed. A recently approved theory states that vitreomacular adhesion with focal contraction of the perifoveal cheloid and pathologic traction can lead to a loss of full-thickness central retina causing a MH. The most valuable diagnostic procedure for MH is optical coherence tomography. Among other useful examinations are fluorescein angiography and angio-OCT. Classification of the stages of development of MH is done with an anatomical Gass classification and the recent The International Vitreomacular Traction Study Group Classification of Vitreomacular Adhesion, Traction, and MH. Natural history of the MH differs in the early and advanced stages. Pharmacological vitreolysis with ocriplasmin is used in the treatment of the disease. The most effective therapy is the posterior pars plana vitrectomy. Dye and peeling of the internal limiting membrane helps to achieve the closure of the MH and the good visual acuity.
Impact of sectoral economic performance and fiscal capacity on public health expenditure in South Africa
Authors: Megbowon Ebenezer Toyin , Zerihun Mulatu Fekadu
Published: July 2024

This study analyses the long-run relationship between, and the direction and magnitude of impact of sectoral economic growth and fiscal capacity on government health expenditure. The study was carried out to validates the Wagner hypothesis from sectoral perspective and revenue-expenditure hypothesis for South Africa for the period 1984–2020. Fully modified least squares and dynamic least squares and canonical cointegration regression were used to achieve the objectives of the study. Empirical regression results showed that there is a negative impact of the secondary sector GDP on public health expenditure. Thus, invalidating the Wagner hypothesis and suggesting that secondary sector GDP cannot serves as an answer for public health expenditure. However, there was a positive relationship between tertiary sector GDP and public health expenditure. The study make case for unceasing provision of an enabling environment that continuously support growth of the tertiary sector.
The development of AUKUS in the Indo-Pacific region and its influence on Indonesia’s policy as a global maritime fulcrum
Authors: Suharto Priyanto , Cempaka Timur Fauzia Gustarina , Sutanto Rudi
Published: July 2024

The trilateral defense and security pact between Australia, the United Kingdom, and the United States has strong impact to the security dynamics in the Indo-Pacific area. This agreement entails a strengthened alliance between Australia and enhanced military collaboration with the United States and the United Kingdom resulting in regional volatility. This paper aims to examine the AUKUS (Australia–United Kingdom–United States Partnership) agreement and the resulting ensuing instability in the Indo-Pacific region, specifically from Indonesia’s perspective. The focus of the research is on the interplay between Indonesia’s diplomacy capability and the military functions of the Indonesian Navy as security policy. This study employs a qualitative approach to delve into in-depth insights into the evolution of AUKUS in the Indo-Pacific region, which triggered a series of responses from many countries subsequent to the announcement of the establishment of the AUKUS Defense Pact. The AUKUS establishment simply reinforces the notion that geopolitical tensions are pulling the area apart. The influence of the AUKUS-China war can jeopardize regional stability since the US and China continuously demonstrate the supremacy of their armaments in order to dissuade one another. The AUKUS-China contest has had a highly adverse impact on Indonesia. This article argues that the Indonesian Navy’s diplomatic prowess is crucial because it has the potential to play a big influence in the Indo-Pacific region’s international political dynamics concerning the South China Sea. Furthermore, the Indonesian Navy must proactively prepare for potential armed conflicts in Indonesian territorial seas by developing a comprehensive maritime policy during times of peace, leveraging its geographical advantages.
Relationship of ESG scores on firm performance: Moderating roles of board size and CEO duality
Authors: Meeprom Sansanee , Boonyanet Wachira , Tongkong Supa
Published: July 2024

The aim of this study is to examine the relationship between Environmental, Social and Governance (ESG) activities and the performance of Thai listed firms. The moderating roles of board size and CEO duality on this relationship are also assessed. The ESG score provided by LSEG (formerly Refinitiv) is chosen to measure ESG activities, both as an overall ESG combined scores and as Environment, Social, and Governance pillar scores. Multiple regression analysis is used to test the impact of ESG on firm performance while the PROCESS macro is used to test the moderating effects. Results reveal that the overall ESG combined score demonstrates no statistically significant effect on firm market-based performance. However, it shows the significant effects on firm performance for both the ESG combined score and the Environmental and Social pillar scores when moderated by board size and CEO duality; Governance pillar score exhibits no significant effect. Additionally, it is found that when the CEO operates only as the managing director and small board size and average board size are evident, higher ESG disclosure scores enhance firm performance. However, when the CEO serves as both managing director and chairman of the board of directors, and where there is a large board size, higher ESG disclosure scores diminish firm performance. This study contributes to the ESG literature and encourages companies to enhance their performance by implementing ESG combined activities with good governance policies.
The principle of legality and sustainable development goals (SDGs): Impact and practices in UAE constitution
Authors: Alfalahi Buti Obaid Saeed , Lamdjad Imane , Alnujaifi Mustafa , Alheety Noaman Atallah
Published: July 2024

The principle of legality constitutes one of the basic principles of the government’s rule of law, and as a result, it has been recognized as one of the most essential guarantees of human rights. The goals of sustainable development have a strong link with the principle of legality, and achievements in accomplishing a goal can frequently contribute to the accomplishment of other goals in addition. The United Arab Emirates’ constitutional framework, regulations, and rules, along with the goals for sustainable development (SDGs), were profoundly affected by the principle of legality. The method in which international standards and laws have been integrated into the UAE’s national legal framework provides definitive proof of this effect. The research concluded that all published and unofficial legal regulations have to be respected in order for public authorities to use within the limits of the principle of legality. These involve adhering to the standards of positive legitimacy and the fundamental regulations the community agrees on.
UM ESTUDO SOBRE INVESTIMENTOS EM FUNDOS IMOBILIÁRIOS COMO COMPLEMENTO PARA A CONSTRUÇÃO DE UMA RENDA PASSIVA NA APOSENTADORIA
Authors: Cubero Bruno Souza das , Viana Sandramara Aparecida da Costa , Aguiar Heraldo Márcio De , Azevedo Viviane Elisabete Ramalho de
Published: July 2024

Considerando o atual déficit do sistema previdenciário brasileiro e a obrigatoriedade da contribuição à Previdência Social, verifica-se um aumento da incerteza em relação à aposentadoria. Este estudo tem como objetivo aprofundar o entendimento sobre os fundos imobiliários e sua viabilidade como opção de investimento complementar de renda passiva a longo prazo. A pesquisa é de cunho qualitativo, de natureza exploratória e descritiva, abrangendo os principais conceitos e teorias relacionadas aos Fundos de Investimento Imobiliários (FIIs) e à aposentadoria no Brasil. Foi realizada uma análise comparativa entre a Caderneta de Poupança e o FII CSHG Logística (HGLG) no período de janeiro de 2018 a dezembro de 2022, a fim de demonstrar a rentabilidade real descontada a inflação (IPCA) e o rendimento distribuído durante esse período. Conclui-se que a Previdência Social enfrenta uma situação delicada que tende a se agravar, devido ao aumento da expectativa de vida e outros fatores que afetam a arrecadação previdenciária. O FII HGLG demonstrou um retorno real positivo, evidenciando sua capacidade de proteção contra a inflação por meio dos reajustes dos aluguéis, além dos rendimentos isentos distribuídos mensalmente. Para pesquisas futuras, sugere-se o uso de indicadores macroeconômicos adicionais, ampliação dos períodos amostrais e inclusão de outros segmentos de FIIs.
The Prediction of Failure in the Gas Filtration System in Low-Pressure Carburising Furnaces
Authors: Kłos Sławomir , CHCIUK Marcin
Published: July 2024

Predictive maintenance is one of the key aspects of Industry 4.0. The article presents the results of experimental tests of nitrogen purification filters in the installation of a low-pressure, metal processing device. The aim of the research was to develop a predictive algorithm for making decisions regarding the replacement of used filters, based on flow analysis and measurement of the pressure difference in front of and behind the tested filter. For the purposes of the research, a special test stand was constructed, which made it possible to determine the operating characteristics of three selected filters. Based on the tests carried out, the limit characteristics of the parameters measured were determined, identifying the need to replace filters in the gas installation.
Novel cold-active amylase-producing bacterium from Chukchi Sea and its enzyme properties
Authors: Kim Min Ju , Kim Jin A , Park Ha Ju , Yim Joung Han , Kim Il Chan , Han Se Jong
Published: July 2024

A cold-active amylase was purified from Alteromonas sp. KS7913 isolated from the Chukchi Sea in the Arctic Ocean. After purification with use of ammonium sulfate precipitation, phenyl column chromatography, and size exclusion chromatography, 200.34 U mg−1 of purified amylase was obtained. The final yield was 3.4%, and the activity was 5.7-fold higher than that of the initial culture broth. KS7913 origin amylase showed a molecular weight of 70 kDa and optimal activity at 25℃, pH 7.0 in Tris-HCl buffer. The amylase was highly active, especially at 5℃, and maintained stability at basic conditions below 25℃. Copper and zinc ions inhibited enzyme activity, whereas manganese, barium, and calcium ions exhibited positive effects. This activity was maintained even in the presence of alcohol. The findings of this study supplement our understanding of cold-active amylases, and may have practical applications in low-temperature industries.
Investigating Posthumanism through the Medium of Self-Representation Using Instagram's Augmented Reality (AR) "Camera Effect"
Authors: Muhammad Alzaki Tristi  , Nisa Rizkya Andika
Published: July 2024

The Augmented Reality camera effects feature on Instagram provides users with the freedom to create, experiment, and share visual content without limitations, thereby presenting diverse self-images. Remarkably, Indonesia, ranking fourth globally in terms of Instagram users in 2022, demonstrates remarkable adoption of this AR camera effects feature, indicating rapid adoption of new media technology. This research investigates how users engage with this technology to redefine their identities and transcend traditional human boundaries. Through a desk study method, this study analyzes the "Camera Effect" feature on Instagram as a focal point for understanding the phenomenon of self-representation and exploring the concept of posthumanism. By referencing Frank Webster's theory of information society and the posthuman concept in literature, this research reveals that the AR feature on Instagram is a powerful cultural medium for self-representation, overcoming limitations between humans and technology in Indonesian Society. Self-representation becomes pivotal in posthumanism, and AR technology enables exploration and experimentation of diverse identities and expressions. Thus, Instagram's AR technology provides users with new ways to represent themselves, transforming the paradigm of representation and self-identity.
Resilience of Participatory Communication Adolescent Community Communities in the Prevention of Child Marriage in Sukabumi
Authors: Utami Yessi Sri
Published: July 2024

This research has an urgency that participatory communication resilience can be formed in communities with young ages, namely adolescents who are members of adolescent communities. This research focuses on how resilience is formed in adolescent communities to prevent child marriage in Sukabumi Regency to improve the ability of adolescents and advocate for vulnerable peers trapped in child marriage. This research uses qualitative research methods with a case study approach to explore the experiences of adolescent members of 5 regional children's forums in Sukabumi as research subjects who actively participate in the prevention of child marriage through the Yes I Do program. The results showed that participatory communication of child communities in preventing child marriage in formal and informal peers showed the collaboration of child communities with diverse cross-communities (heteroglacia). In addition to heteroglacia, Wabinar Activities are open dialogue and sharing experiences and knowledge with peers (dialogue) Movie watching and business class activities are a process to unite some of the differences that exist into an understanding about the impact of child marriage (polypony). Youth Camp and Watch Together activities filled by the children's community are a form of fun participatory communication (carnival). The children's community builds meaning, persistence, self-confidence, patience, independence or what is referred to as peer resilience with peer education activities.   Resilience in adolescents who are vulnerable to being trapped in child marriage is an important period and affects the basis of adulthood, individual changes and life development.
Leveraging the S-O-R Framework to Determine Tourists' Willingness to Revisit Riau Island
Authors: Keni Keni , Wilson Nicholas , Adrianto Fajri , Dharmawan Purnama , Teoh Ai Ping
Published: July 2024

Despite being a popular destination, Riau Island's tourist numbers have declined as of April 2024, and remain lower than those of other Indonesian destinations. Therefore, prompt actions are needed to increase the number of visitors. Therefore, using the stimulus-organism-response (S-O-R) framework, this research delves into the intricate factors that mold individuals' propensity to revisit Riau Island. Employing a survey-centric methodology, an extensive dataset was scrupulously amassed from eligible participants through the deployment of digital questionnaires. Stringent criteria were implemented via purposive sampling, ensuring respondents had frequented Riau Island at least thrice in the preceding two years. The two-month duration of data collection yielded a robust dataset, encompassing a total of 154 responses. The analysis, executed using the Partial Least Squares (PLS) method in SmartPLS 4 software, validates the affirmative impact of both destination quality and destination source credibility on tourist satisfaction and the willingness to revisit. Furthermore, the results disclose that tourist satisfaction functions as a positive mediator in these relationships. This implies that the perceived destination quality and source credibility indirectly contribute to the probability of future visits by positively influencing the overall satisfaction of tourists. These findings not only enrich people’s understanding of the determinants influencing individuals' choices to revisit a destination, but also present valuable implications for enhancing destination management and marketing strategies, ultimately aiming to elevate the overall tourist experience. In essence, this study adds to a refined comprehension of the dynamics underlying repeat visitation behaviors, opening avenues for strategic interventions in the tourism sector.
Application Of Edible Coating Aloe Vera On Langsat Punggur Pontianak To Extend Shelf Life
Authors: David Haloho Jhon , Liwu Suzanne Laura , Barlina Rindengan , Wungkana Jerry
Published: July 2024

Langsat Punggur Pontianak has a high economic value in West Kalimantan, because it involves the thousands of workers who win it. Langsat Punggur Pontianak has unique nutritional and organoleptic characteristics. The purpose of this study was to evaluate the effectiveness of using edible coatings from aloe vera in extending the shelf life of Langsat Punggu Pontianak. The research was conducted at the Food Technology and Nutrition Laboratory, Faculty of Agriculture, Tanjungpura University, Pontianak, from June 2022 to September 2022. The parameters for the tests carried out included weight loss, moisture content, TSS, texture, color, taste, aroma. The results showed that the use of edible coatings combined with cold temperatures could extend the shelf life to 15 days, and if Langsat Punggur Pontianak was stored at room temperature the shelf life would reach 10 days
Development Strategy of Leading Agricultural Commodities: Findings From LQ, GRM, and Shift-Share Analysis
Authors: Marina Ida , Mukhlis Mukhlis , Oksifa Rahma Harti Adi
Published: July 2024

This research aims to develop the potential of food crops as a first step in the development planning process. This research was conducted in Majalengka Regency and has resulted in three main studies. First, it identifies staple and non-staple food crops in the region. The data source used consists of time series data from 2018-2022, and primary data with sample determination using the Proportional Random Sampling method. The results of the analysis show that staple food crops in Kabupaten M consist of rice, corn, soybeans, peanuts and green beans, while non-staple food crops include cassava and sweet potatoes. Secondly, the study also indicated that rice is the main food crop in the region. Finally, maize and groundnuts were identified as priority crops for further development. These findings provide valuable information for agricultural development planning, focusing on the development of potential commodities.
Clinical experience in managing patients with lymphogranuloma venereum
Authors: Plakhova Xenia I. , Katunin Georgiy L. , Abuduyev Nazirbek K. , Vasiliev Mikhail M.
Published: July 2024

The article presents two clinical cases of lymphogranuloma venereum with classic manifestations of the disease. In the first case, the stages of lymphogranuloma venereum can be traced: the appearance of a primary affect (ulcer on the penis), the development after a few weeks of regional (inguinal) lymphadenitis and proctitis (anorectal syndrome). On the background of prescribed antibiotic therapy according to the regimen: doxycycline at a dose of 100 mg twice a day for 21 days, the clinical manifestations completely resolved. The second case is interesting in the development of the clinical picture of lymphogranuloma venereum from the second stage of the disease (inguinal syndrome) and the ineffectiveness of treatment with doxycycline, which subsequently required surgical intervention. In addition, in this case, Chlamydia trachomatis DNA was initially detected in a urethral scraping without evidence of urethral inflammation, which is rare for this disease. To treat a patient with “inguinal syndrome” as a clinical manifestation of lymphogranuloma venereum, a fluoroquinolone antibiotic, levofloxacin, was successfully used according to the regimen 500 mg twice a day for 28 days.
Rastreio de tecnologias digitais em saúde (DHTs) em Laboratórios de Anatomia Patológica
Authors: Pereira Fernanda Silva , Silva Maísa Vilas Boas , Lima Sthefanie Caroline Rodrigues de , Machado Jaqueline da Rosa , Pereira Rodrigo Machado
Published: July 2024

Objetivo: rastrear as tecnologias digitais em saúde (DHTs) em Laboratórios de Anatomia Patológica e descrever as que foram citadas entre 2016 e 2021. Métodos: neste estudo, foi realizada uma revisão integrativa de literatura para identificar artigos sobre softwares, scanners, aplicativos e sistemas de informações laboratoriais aplicados à laboratórios de patologia. A pesquisa abrangeu artigos publicados até julho de 2021. Resultados: foram identificados 71 estudos, sendo 26 analisados detalhadamente. Estes artigos apresentaram 78 DHTs, categorizados em cinco funcionalidades principais: Softwares de macroscopia, Digitalização de lâminas, Gerenciamento e Visualização de imagens, Análise de imagens e Sistema de Informação Laboratorial (LIS). Os benefícios das DHTs incluem maior precisão diagnóstica, compartilhamento remoto de dados e imagens, redução de tempo no diagnóstico, além de auxiliar na padronização e gestão de informações. Considerações finais: as tecnologias mencionadas neste estudo promovem avanços significativos na área da Anatomia Patológica, oferecendo melhorias na precisão dos exames, diagnóstico e tratamento.
Apendicite aguda em crianças
Authors: Guedes João Victor Cordeiro , Dornas Mariana Bernardes , Prates Julio Barretto , Urgal Filho Fabrício Gonçalves , Pereira Luiza Valadares e , Moraes Júnior Célio Carvalho de
Published: July 2024

Objetivo: Caracterizar sobre a epidemiologia, a etiologia, os sinais e sintomas, o diagnóstico, o tratamento e as possíveis complicações da apendicite aguda em crianças. Métodos: Foi feita uma pesquisa bibliográfica descritiva, realizada no período de 2004 a 2024, no idioma português e inglês, no mecanismo de busca do Google Acadêmico, e nas bases científicas da SciELO e Acervo+ Index Base. Resultados: Foram referenciados 20 trabalhos que demonstraram a questão envolvendo a apendicite, que é uma inflamação aguda do apêndice, podendo ser causada por uma obstrução do órgão, seja por inflamação da parede ou por um fecalito ou um apendicolito. A apendicectomia em crianças é a forma mais comum de tratamento, podendo ser realizada por laparoscopia ou aberta. Demonstrou-se os principais sinais e sintomas que as crianças apresentam, destacando a importância do diagnóstico precoce. Considerações finais: A apendicite aguda em crianças é uma condição comum e potencialmente grave que requer avaliação clínica rápida e precisa e tratamento adequado e oportuno. A mesma pode ser causada por vários fatores que levam à obstrução da luz do apêndice, resultando em inflamação, isquemia, necrose e perfuração do órgão.
Acrodermatitis Enteropathica Following a Pull-Through Procedure
Authors: Koroma Foday , Fung Hayden , Amara Shivkar , Lebwohl Mark
Published: July 2024

Abstract
Introduction: Acrodermatitis Enteropathica is a rare condition traditionally expressed by perioral or acral dermatitis, diarrhea, and alopecia. Acrodermatitis Enteropathica can be inherited or acquired, with the acquired form linked to zinc deficiency. The pull-through procedure is a method used to treat Hirschsprung’s disease, a condition in which the large intestine is missing nerve cells that make it difficult to pass stool, which can lead to obstruction and absorption issues. Complications of pull-through procedures have been associated with bowel obstruction and malabsorption of essential nutrients, including zinc.
Case Report: We present a 16-month-old male who developed perioral dermatitis, well-demarcated erythematous plaques, and alopecia after a pull-through procedure related to Hirschsprung’s disease.
Discussion: Acrodermatitis Enteropathica can present with various cutaneous lesions, and dermatologists should be familiar with the differing morphologies. In this paper, we encourage dermatologists to consider Acrodermatitis Enteropathica as a differential diagnosis for patients who develop cutaneous lesions following pull-through procedures.
 
Keywords: Acrodermatitis Enteropathica, Hirschsprung’s Disease, zinc deficiency, case report
Pityriasis Rubra Pilaris Following Administration of the Pfizer-BioNTech COVID-19 Vaccine Successfully Treated with Acitretin and Dupilumab
Authors: Hoopes Raquel , De Moll Ellen
Published: July 2024

Introduction: Pityriasis rubra pilaris (PRP) is an inflammatory eruption of unknown origin; rare cases of COVID-19 vaccine-induced PRP have been reported. Here, we present a case of COVID-19 vaccine-induced pityriasis rubra pilaris inadequately managed with acitretin, successfully treated with the IL-4/IL-13 inhibitor dupilumab.
Case Report: A 76-year-old male presented to an outpatient dermatology clinic with a 2-month history of a profoundly pruritic worsening rash characterized by large, orange-salmon-colored follicular papules with scale coalescing into plaques covering approximately 80% of the body surface area. The plaques had well-defined borders and multiple islands of sparing characteristic of PRP. Multiple therapies were trialed with no improvement, including oral prednisone, mycophenolate, topical corticosteroids, antiparasitics, antifungals, doxepin, and UVB treatments. A trial of oral acitretin resulted in improvement of the skin plaques and keratoderma, but the patient remained uncontrollably pruritic. Dupilumab was initiated which provided rapid relief, and the patient has remained clear for several months.
Conclusion: Clinicians should be aware of dupilumab’s potential for effective treatment of PRP with recalcitrant pruritus.
Drug-Induced Sweet’s Syndrome by Xcopri
Authors: Wong Summer , Kowalczyk Chris , Karim Rehan , Skopit Stanley , Kerdel Francisco
Published: July 2024

Background: Sweet's syndrome (SS) is a relatively rare, self-limiting dermatological condition predominantly affecting women aged 30-50. It is characterized by the sudden onset of erythematous plaques, nodules, or papules on the skin and is often accompanied by fever, leukocytosis, and systemic symptoms. While most SS cases are idiopathic, approximately 5% are drug-induced.
Case: This case report describes a 34-year-old female with a medical history significant for epilepsy who presented with diffuse erythematous papules on the bilateral upper extremities. The onset of these symptoms coincided with the initiation of Xcopri (cenobamate tablets) in her medication regimen.
Conclusion: To our knowledge, this report highlights the first case of Xcopri-induced SS. We interpret this patient's presentation as a cutaneous response secondary to an adverse drug reaction and aim to emphasize the importance of obtaining a thorough medication history at each clinical consultation.
Successful Treatment of Refractory Discoid Lupus Erythematosus with Deucravacitinib
Authors: Sohn Alice , Bouché Nicole , Lewitt George Michael , Song Eingun James
Published: July 2024

Discoid lupus erythematosus (DLE) is the most common subtype of chronic cutaneous lupus erythematosus (CLE) that may present with or without systemic lupus erythematosus (SLE). Treatment for DLE remains limited, as there are no medications specifically approved to treat DLE. Deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 (TYK2) inhibitor, is currently being studied for adults with moderate-to-severe discoid and/or subacute CLE. We report a case of successful treatment of refractory DLE with deucravacitinib.
A 65-year-old female with a longstanding history of systemic lupus erythematosus presented with prominent discoid lesions involving the nose, cheeks, and mid upper cutaneous lip. Having tried topical medications, multiple courses of systemic steroids were attempted, but the patient flared shortly after the tapers. Despite the patient experiencing some improvement on mycophenolate mofetil and prednisone, the decision to switch to deucravacitinib was made due to the patient developing multiple infections while on the former regimen. Three months after starting deucravacitinib, the patient returned with their skin completely clear.
A better understanding of the molecular pathogenesis of CLE is informing the development of more targeted therapeutic strategies. TYK2 and Janus Kinases (JAKs) both mediate the signaling of cytokines, some of which play a role in the pathogenesis of SLE. Deucravacitinib binds to TYK2 at the regulatory domain, which is unique to its respective kinase unlike conventional Janus Kinase (JAK) inhibitors that bind to the active domain conserved across all JAKs. Deucravacitinib offers more targeted inhibition with a potentially improved safety profile compared to conventional JAK inhibitors.
Significant Improvement of Persistent Hailey-Hailey Disease with Dupilumab: A Case Report
Authors: Ramesh Malvika , Chellappan Brinda , Ross Lindy
Published: July 2024

Hailey-Hailey disease is a rare, genetic blistering disease characterized by erythematous, scaly plaques in intertriginous regions such as the axillary, inframammary, and groin regions. The plaques cause discomfort and are difficult to treat. Treatment ranges from topical to systemic and surgical. Despite the variety of treatment options, Hailey-Hailey disease is notoriously difficult to treat with each patient responding uniquely to treatment. There has been evidence of patients with Hailey-Hailey disease experiencing improvement of symptoms with dupilumab injections. Dupilumab has several off-label uses, including allergic contact dermatitis, hand dermatitis, chronic spontaneous urticaria, and alopecia areata, showing promise for its use in dermatology outside of atopic dermatitis and prurigo nodularis. Due to its minimal side effects, dupilumab can be tried for Hailey-Hailey disease with little risk. We present the case of a 37-year-old female with recalcitrant Hailey-Hailey disease who noticed significant improvement on dupilumab.
Perspectives Regarding Virtual Interviewing for Dermatology Residency in the United States: A Survey of Applicants, Residents, Faculty, and Program Directors in the 2022-2023 Application Cycle
Authors: Norman Thomas , Guenther Jana , Lafeir Marie D. , Worswick Scott
Published: July 2024

Background: Despite the widespread adoption of virtual interviewing for dermatology residency in the United States (US), there are limited data on the perspectives of those affected.
Objectives: Characterize the viewpoints regarding virtual interviewing of applicants, residents, and faculty who participated in the 2022-2023 US dermatology residency application cycle.
Methods: Two anonymized surveys were created: one for applicants and the other for programs (residents, program directors, and other faculty). The program survey was distributed through the US Dermatology Program Director listserv in January 2023. The applicant survey was distributed through email in April 2023.
Results: There were 336 respondents: 135 applicants, 63 program directors, 77 other faculty, and 61 residents. Overall, the largest proportion favored virtual-only interviewing (39%), followed by some combination of in-person and virtual interviews (28%) and in-person–only interviewing (20%). There was no significant difference between preferences of applicants and program directors (P=0.13). The respondents’ most supported changes for future application cycles were limiting the number of programs to which an applicant can apply (34%), limiting the number of interviews an applicant can accept (30%), and providing funding for applicants with demonstrated need (13%).
Limitations: Our study may be limited by the response rates, estimated to be 21% for applicants and 45% for program directors. 
Conclusion: Given the range of preferences, we would not advocate for requiring virtual-only interviewing at this time for our specialty. Instead, reforms should prioritize the respondents’ most supported changes for future application cycles.