bluuebunny/crossref_metadata_2025 huggingface dataset:
In the Foot Step of Consolidating Ummah: Highlights from the 7th Indonesian Muslim Congress
Authors: Garadian Endi Aulia
Published: April 2020

Indonesia might be considered as "fortunate". In fact every five years, and often to concur one year after the election took place, Indonesian Muslims have a routine assembly called the Indonesian Muslim Congress (Kongres Umat Islam Indonesia, KUII). The Congress has reached the seventh (KUII VII) in 2020, and one of the its main goals is to consolidate Indonesian Muslims. On top of that, acting as a facilitator, the Indonesian Ulema Council (MUI) through this congress also aspires that Muslims in Indonesia to become the finest community (khayra ummah), to realize the unity of the people (tawhidul ummah), to achieve empowerment of the people (taqwiyatul ummah), to mainstream wasathiyah al-Islam (center and moderate Islam) as well as Islam rahmatan lil alamin, and to install religious values as a spirit of devotion to the nation and state. All of these goals are covered under the grand theme of the congress entitled "Strategies for the Struggle of Indonesian Muslims to Achieve Advanced, Fair and Civilized of Indonesia".
Podziały przestrzeni Europy Środkowo-Wschodniej
Authors: Pietraś Marek
Published: April 2020

In the article, referring to quantitative indicators, the subject of analysis is the identification of the dividing line of the previously shared space of Central and Eastern Europe. This means that this part of Europe is changing, shifting the previous dividing line. This line during the Cold War symbolically ran along the Elbe River, dividing Europe into two opposing political, military and ideological blocks. The new dividing line has been symbolically shifted from the Elbe River to the Bug River and concerns political, economic and social standards. It is therefore a multifaceted phenomenon. Strengthening the division occurs, on the one hand, between the countries that joined the European Union, and on the other, which remained in the post-Soviet area.
Polityka traktatowa Polski w zakresie umów o przyjaźni i współpracy po „Jesieni ludów” 1989 r.
Authors: Staszewski Wojciech Szczepan
Published: April 2020

A state’s treaty policy constitutes a significant aspect of the foreign policy to every country. The transformations in Poland and in the other Central and Eastern European countries launched by the events described as “Autumn of Nations” of 1989 have brought fundamental changes to the several governments and the international community, including Poland’s, which demanded a revision of the Polish treaty policy. Due to the fact that the bilateral Treaties of Friendship and Cooperation reflect the priorities of foreign policy and indicate the characteristics of the bilateral relations, they play particularly important role in the treaty relations of every country. Through the outlook on the transformations in the Polish treaty policy with respect to the Treaties of Friendship and Cooperation made after the governmental changes, this paper attempts to present the interest areas for the Polish foreign policy after 1989.
Koniec zimnej wojny, transformacja Europy Środkowej i Wschodniej a moc eksplanacyjna i prognostyczna teorii stosunków międzynarodowych
Authors: Podraza Andrzej
Published: April 2020

The aim of the article is to show the explanatory and prognostic power of theories of international relations (neorealism, neo-liberal institutionalism and social constructivism) in the situation of visible problems with predicting the end of the Cold War and explaining the democratization process in the countries of Central and Eastern Europe and other parts of the world. In the face of significant changes that have influenced the formation of a new post-Cold War international order, it is necessary to consider the importance of the theory in adopting appropriate research strategies so that on the one hand, it is possible to predict the course of events with some degree of probability and on the other, to explain their essence and importance. The end of the Cold War and the process of transforming the countries of Central and Eastern Europe thus pose a general and extremely important question about the possibility of developing a scientific approach to the analysis of international relations, which goes beyond only short-term observation of current events. The article analyzes the most important theoretical approaches in the context of adopting such a research strategy, thanks to which one could depart from the dominance of extreme, mutually exclusive positions. The great debates that have been held so far have shown that wealth in science is not a one-sided approach, even if at some point or time we are dealing with the supremacy of a particular theory or a methodological approach. The fiasco of the science of international relations in predicting the end of the Cold War has shown the necessity of undertaking such activities whose task would be to combine rather than exclude. The end of the Cold War and the transformation process of Central and Eastern Europe are therefore treated as case studies that help in testing the theory of international relations as adequate instruments for analyzing the changing international situation.
EVALUATION AND SELECTION OF A FLEET OF AIRCRAFT LOCATED IN MADNIAH, SAUDI ARABIA
Authors: Harasani Wail
Published: April 2020

The present work simulates the evaluation and selection of a fleet of aircraft for a proposed airline located in Madniah, Saudi Arabia, to operate across an assumed network that includes both local and international destinations. This simulation is conducted through a series of phases and subsequent deeper and meticulous levels of analysis. At the end of these phases some recommendations are given for selecting the suitable fleet. The phases are simulated using MS Excel and the output of the study predicts both the aircraft efficiency and its contribution to the net profit of the airline. Considering the destination ranges covered within the network and such other important criteria as the respective payloads, a number of candidate aircraft were chosen for the study. Finally, it was found from the study that 5 of the EMB170 aircraft would be the best choice for the proposed airline.
FORECASTING METHODS AND ICAO’S VISION OF 2011-2030 GLOBAL AIR TRAFFIC
Authors: Yao Jinjin , Yu Haiyang , Anwar Zubair
Published: April 2020

Forecasting has been a key factor in the planning and development of civil aviation. This paper surveys current techniques in air traffic forecasting. The advantages and disadvantages of the techniques, as well as the criteria for selecting of a particular technique are discussed. Then, the forecasting work of the International Civil Aviation Organization (ICAO) is comprehensively introduced, i.e. the traffic data, the methodological framework, and the major models. It involves ICAO’s practices under this subject in the last two decades. ICAO’s forecasting has long been a reliable reference for its 191 member states. In this paper, main results of ICAO’s up-to-date forecasts of 2011-2030 global air traffic, both passengers and cargos, are conveyed.
DOES PERTAINING TO A GLOBAL STRATEGIC ALLIANCE IMPROVE THE BOTTOM LINE?
Authors: Perezgonzalez Jose
Published: April 2020

This study researched whether pertaining to a global strategic alliance brought significant benefits to the ‘bottom line’ of allied airlines. The study used two groups: a group of airlines which had joined one of three global alliances against a control group of airlines which had not joined any alliances. The research compared the net return of those two groups before and after airlines joined their alliances (or equivalent measure), as well as their relative net performance both in the short-term and in a longer term. Results showed a sensible deterioration in net profitability for the alliance group and a perceptible improvement in net profitability for the nonalliance group. The latter also differed from the former in having a positive relative net performance in the short-term.
IMPACT OF THE NEW DISTRIBUTION CAPABILITY (NDC) STANDARD ON FUTURE AIRLINE DISTRIBUTION – A CRITICAL ANALYSIS
Authors: Ziegler Yvonne , Troester Jörg , Sazali Abdul Mu’ti
Published: April 2020

In 2012 IATA has initiated a new communication standard in airline distribution called New Distribution Capability (NDC) that will enable airlines, IT providers, and travel agents to work together to create new capability in the distribution of airline products and services as well as to simplify the business. NDC has been introduced to solve limitations of the existing programs in the distribution system and to represent the modernization of future air travel distribution. NDC standard intends to give a potential impact on future airline distribution where airlines will have wider opportunities to directly interact with intermediaries and reduce commission fees to the Global Distribution System (GDS). This study, in particular, confirms that airline distribution specialists firmly believe that NDC constitutes an important development in the airline industry and, while still being in its development stage, it clearly has the potential to address today´s market issues and to solve tomorrow´s challenges.
MEMBANGUN SPIRITUALITAS BERDASARKAN SURAT 1 TIMOTIUS 4:12
Authors: Gulo Manase
Published: April 2020

Life in this day and age is shaped by various elements that influence one another, so that each person becomes a unique person. Influence comes from family background, social culture, economic factors and bad habits, depending on the environment in which a person lives. Paul wanted to talk to them as spiritual people, but he found that they were still "babies" he could only give them milk, because they were still not ready to receive hard food (1 Cor 3: 1-3). Spirituality is an important part of human life, with a healthy spirituality humans will live life well. Spiritualiats are an important force in sustaining our lives, through good spirituality humans can deal with bad conditions. Through the advice of the Apostle Paul to Timothy we get important principles to build spirituality.
PANDANGAN ALKITAB TENTANG OKULTISME
Authors: Dilla Minggus
Published: April 2020

Occult practices have occurred since time immemorial, and even today occult practices cannot be separated from the lives of believers and humans in general. What are occult practices and how can occult practices occur and what are the impacts on human life. In this paper, the author will explain the biblical view of the occult and its ins and outs so that believers can know and be able to avoid various kinds of occult practices that are around us.
Internal Conflicts in Works of Thucydides and Machiavelli
Authors: Šedo Jakub
Published: April 2020

Hybrid threats are considered among the most serious risks that Western societies currently face. The aim of actors using such threats is to influence decision-making processes, and in order to do so they use a rich spectrum of methods to instigate conflict in society, seeking to undermine trust in institutions, abet radicalisation, and so on. Activities aimed at creating internal conflict, and the prevention of such activities, are not, of course, a new phenomenon; they differ only in their extent, intensity and the techniques used. The aim of this paper is to investigate how classic strategists - Thucydides and Machiavelli - described in their works how internal conflict is fomented among the enemy and how it can be prevented. The paper describes and analyses various ways of instigating and mitigating internal conflict as noted in their works, and assesses their relevance for the current debate.
Criteria of Mobile Psychotherapy Games for Memory Disorder: A Systematic Literature Review
Authors: Sie-Yi Laura Lim , ChePa Noraziah
Published: April 2020

Games have been widely used in many domains including medical for therapy purposes. With the advancement of technology, mobile psychotherapy games have essential role in improving memory among elderly patients. There are numbers of psychotherapy games that have been developed for elderly with memory disorder. However, at one point most of the developed games are still questionable since there is lack of game development guides for this particular purpose. Designing the optimum design for the psychotherapy games, which emphasizes the users in it will be able to maximise the effectiveness of the games. Thus, this study aims to review the literatures systematically in identifying the criteria for mobile psychotherapy games specifically for memory disorder. To achieve this, three databases were used in searching literatures which are Scopus, Web of Science and ACM Digital Library. The search identified 992 articles altogether;69 papers remains for further selection process while 909 were excluded due to irrelevancy of the focus. The selection process later refrained to 16 articles being analysed and synthesised. The selection incorporated all articles which focused directly on the psychotherapy games for memory disorder elderly patients concentrated on mobile devices. As a result, a set of important criteria for different themes on designing mobile psychotherapy game has been identified. Significant features of psychotherapy games were found in majority of the reviewed articles. These criteria will be beneficial in forming a guideline for designing and developing mobile psychotherapy games for memory disorder patients.
Application of Fireworks Algorithm in Bioinformatics
Authors: Zhang Yuchen , Lei Xiujuan , Tan Ying
Published: April 2020

Fireworks Algorithm (FWA) has been applied to many fields in recent years, showing a strong ability to solve optimization problems. In this chapter, FWA is applied to some research hotspots in bioinformatics, such as biclustering of gene expression data, disease-gene prediction, and identification of LncRNA-protein interactions. This chapter briefly introduces some backgrounds of bioinformatics and related issues. Through corresponding bioinformatics' problems to optimization problems, some specific optimization functions are constructed and solved by the Fireworks Algorithm. The simulation results illustrate that the fireworks algorithm shows high performance and potential application value in the field of bioinformatics.
Beyond Funding
Authors: Peritore Nicole R. , Lianekhammy Joann
Published: April 2020

The Rural Child Poverty Nutrition Center (RCPNC) was created through grant funding from the United States Department of Agriculture Food and Nutrition Service and designed to address childhood food insecurity in persistently poor, rural counties in the United States. The RCPNC selected various community projects that focused on child nutrition assistance programs. Administration and technical assistance from the RCPNC allowed for improvements to child nutrition programs for the sub-grantees through the grant beginning with community needs assessments and programming meeting their individual needs. Evaluation found that the RCPNC was successful in assisting the sub-grantees reach their unique goals, which improve the initial outcomes as desired by the grant. Additionally, despite the unique communities the sub-grantees served, there were commonalities that linked all of the communities. This chapter describes the process with which the RCPNC sought unique communities with creative projects and explains the ways in which others can improve child nutrition outcomes.
Improved Patient Safety Due to Catheter-Based Gas Bubble Removal During TURBT
Authors: Fritzsche Holger , Ataide Elmer Jeto Gomes , Boese Axel , Friebe Michael
Published: April 2020

TURBT (transurethral resection of bladder tumor) is a standard treatment for bladder cancer. Gas bubble formation is caused by the heating of the RF-electrode from the resectoscope, which causes visual impairments and can also lead to explosive gas formation. The purpose of this work is to find a proper technical solution for removing the air bubbles and toxic gases during electro-resection thereby providing patient safety as well as better operating comfort for surgeons. A continuously controlled irrigation system and catheter based simultaneous suction system was designed, implemented and tested, with an average removal rate of 70% of the air bubbles and gases that appeared inside the urinary bladder. The setup was tested using a dedicated phantom.
Intellectual Property Rights Protection in Nigeria
Authors: Titilope Afolayan Oluyinka
Published: April 2020

Intellectual property right protection is of growing importance in most countries of the world due to its role in the development of any nation. However, intellectual property rights protection in Nigeria has not yielded any positive results as expected due to the problem of weak enforcement and non-implementation of protection laws. In view of this, the main purpose of this article is to unravel the challenges militating against the protection of intellectual property rights of creators and inventors in Nigeria. This article further discusses the benefits of intellectual property rights protection. Challenges contributing to weak enforcement of intellectual property rights were also identified in this article. In conclusion, intellectual property rights protection in Nigeria should be given the highest priority by government to aid national development as well as promoting creativity and innovation on the part of creators and inventors.
Truth telling in Australia's historical narrative
Authors: Mencevska Iva
Published: April 2020

As it stands, the Australian narrative solely reflects the truth of the European settler with little acknowledgement of the truths of First Nations people. In light of Australia’s most recent truth telling project, this essay explores various truth telling projects throughout Australian history, their impact on the national narrative and critically examines the political goal of reconciliation.
Can historians tell the truth? The Uluru Statement from the Heart and the quest for a new history
Authors: Wakamatsu Ansel
Published: April 2020

Following the Uluru Statement from the Heart, historians are again tasked with ‘telling the truth’ about past human rights abuses in Australia. However, I argue that such a demand is too simplistic, and it is better to understand historians as producers of impermanent historical narratives which are embedded in public memory through the historian’s discursive authority and the authority of a supporting truth commission.
Optimum design of the double roll rotary forging machine frame
Authors: Shi Lei , Zhu Chun Dong , Liu Xin , Zhang Yi
Published: April 2020

Abstract. The equipment to realize the rotary forging technology is called the rotary forging machine. Compared with the common forging equipment, machine frame will bear a large torsion force in the working process, and the load in the forming process will eventually act on the rotary forging machine frame, and cause it to deform, thus affecting the rolling situation of the workpiece. Therefore, good frame performance is the premise to achieve stable rotary forging. The good performance of the frame is closely related to the structural design and structural optimization. However, at present, there are few researches on the overall optimization design of the rotary forging machine, and the lightweight technology has become the current trend. In the early manufacturing of low tonnage rotary forging machine, the lightweight design is not paid enough attention to, even if it meets the use performance, but the machine is bulky, which seriously reduces the utilization rate of materials and increases the manufacturing costs. In this paper, based on the existing rotary forging machine, the topological optimization of the main body of the rotary forging machine is carried out, and then the sensitivity analysis of the thickness of each component of the machine frame to the performance of the frame is studied, which provides the basis for the follow-up size optimization. Finally, the experimental verification is carried out, and it is found that the work pieces of the rotary forging are relatively good, which shows that the optimization scheme is reasonable and can be reduced on the premise of satisfying the performance weight, saving manufacturing cost.
Milk yield and somatic cells in dairy ewes with respect to their mutual relations
Authors: Oravcová Marta , Tvarožková Kristí­na , Tančin Vladimí­r , Uhrinčať Michal , Mačuhová Lucia
Published: April 2020

The objective of this study was to analyze milk yield and somatic cell count (SCC) expressed as somatic cell sore (SCS) in Lacaune dairy breed. Data from milk performance testing recorded between 2016 and 2018 (farm in West Slovakia) were used. A total, 377 individual milk yield and SCC records of 61 ewes (first, second and third lacation, respectively) were analysed. Mixed model for milk yield included fixed factors: SCC class (lowest, low, middle, high and highest), year of measurement, lactation number, month in milk and interaction between month in milk and SCC class, and random factors of ewe and error. Mixed model for SCS included milk yield class (lowest, low, middle, high, highest), year of measurement, lactation number, month in milk and interaction between month in milk and milk yield class. Random factors of ewe and error were considered as well. Milk yield was significantly affected ( p <0.05 or p <0.01) by all investigated factors. Except for interaction between month in milk and milk yield class, the remaining factors significantly affected (p <0.05 or p <0.01) also SCS. The analyses confirmed that SCC may be used as a useful indicator of udder health. It may help in identifying infected ewes, and thus, avoiding mammary infections to be spread throughout the whole flock.
Experimental-Phonetic Analysis of Suprasentential Units in the English Language
Authors: Gurbanova Lala Gadir
Published: April 2020

The current article deals mainly with the suprasentential units in English and their characteristic peculiarities. Some viewpoints of western, Russian and Azerbaijani linguists are discussed here. One of the important matters discussed here is to distinguish the notions “text” and “suprasentential units”, which was possible owing to the viewpoints and investigations of specialists in this field. To determine “suprasentential units”, some other terms such as, “micro-text” and “macro-text” are discussed here, too.

To get a detailed information on “suprasentential units”, phonetic experiment was carried out. The essence of the article is to determine the phoneticparameters of “suprasentential units” in the form of a short text. The experiment was realised at the Institute of Linguistics of the National Academy of Sciences of Azerbaijan. For acoustic analysis of the recorded materials, “Speech Analyser”, “WinCecil”, “PRAAT”, “MacSpeech Lab” programs have been used. In the acoustic analysis of speech signals of the given short text, the valuable “PRAAT” computer program created by the professors of Amsterdam University Paul Boersman and David Veenik has been widely used. “PRAAT” computer program has wide opportunities, such as to hold ossillographic and spectographic analysis of language materials (in our case, short texts), to get indicators of tonal frequency intensity, and length of language materials, etc. The above mentioned computer program provides specialists and learners with the chance of learning speech fragments having the recording time from several m/sec to several hours.
Environmental aspects of electromobility development in the Visegrad Group countries
(Aspekty środowiskowe rozwoju elektromobilności w państwach Grupy Wyszehradzkiej)
Authors: Burchart-Korol Dorota
Published: April 2020

Road transport is one of the primary sources of environmental impact. The article presents the ecological assessment of electric vehicle battery charging in the Visegrad Group countries (Czechia, Poland, Slovakia, and Hungary), considering the structure of electricity generation in each country in 2015-2050. The analyses concerned greenhouse gas emissions in the Visegrad Group countries, considering the charging of the vehicle's battery from the power grid. Poland now has the highest greenhouse gas emission indicators for charging electric cars among the Visegrad Group countries, and it is also expected in the future, while Slovakia the lowest. Greenhouse gas emissions are the lowest when electricity used to charge electric vehicle batteries comes from renewable sources. The analyzes provided new knowledge regarding the development of electromobility in the Visegrad Group countries and related to its potential impact on the environment.

Transport drogowy stanowi jedno z głównych źródeł oddziaływania na środowisko. W artykule przedstawiono ocenę środowiskową ładowania akumulatora pojazdu elektrycznego w państwach Grupy Wyszehradzkiej (Czechy, Polska, Słowacja i Węgry) uwzględniając strukturę wytwarzania energii elektrycznej w poszczególnych krajach w latach 2015-2050. Analizy dotyczyły emisji gazów cieplarnianych w krajach Grupy Wyszehradzkiej uwzględniając ładowanie akumulatora pojazdu z sieci elektroenergetycznej. Największą wartość wskaźnika emisji gazów cieplarnianych, która jest związana z ładowaniem pojazdów elektrycznych w państwach Grupy Wyszehradzkiej obecnie, jak i w przyszłości, uzyskano dla Polski, natomiast najmniejszą - dla Słowacji. Wykazano, że w przypadku wykorzystania energii ze źródeł odnawialnych do ładowania akumulatorów pojazdów elektrycznych, emisje gazów cieplarnianych są najniższe. Przeprowadzone analizy dostarczyły nowej wiedzy odnośnie rozwoju elektromobilności w Grupie Wyszehradzkiej i związanego z nim potencjalnego wpływu.
Guidance-Based Motion Planning of Autonomous Systems
Authors: Özkan Bülent
Published: April 2020

Motion planning is a significant stage in the control of autonomous systems. As an alternative method, guidance approach is proposed for the motion planning of those systems. In guided munitions, guidance laws determine the success of the guidance systems designed to steer systems such as missiles and guided bombs towards predefined targets. The guidance laws designated according to determinative agents such as the firing position of the munition, target type, and operational requirements try to provide the munition with arriving at the target point even under the disturbing effects. In this study, the applicability of the guidance laws to autonomous systems is investigated in a manner similar to the approach for the guided munitions. For this purpose, the motion planning of the selected robotic arm, tracked land vehicle, and quadrotor is tried to be performed in order to move them to predefined target points. Having designed the control systems compatible to the selected guidance laws for the considered systems, the corresponding guidance scheme is constructed. Eventually, after conducting the relevant computer simulations, it is observed that the desired target chase can be made in a successive manner for all cases.
Alzheimer’s Disease Neuroprotection: Associated Receptors
Authors: Barros Câmara Alice
Published: April 2020

Research with humans and animals has been developed over the past few years to identify receptors involved in Alzheimer’s disease, aiming at a better understanding of the mechanisms and pathophysiological aspects associated with the disease. Such receptors, whether or not directly associated with current AD therapy, are relevant since their blockage or activation might result in improving or worsening the clinical scenario of the disease. In other words, such receptors might be involved in the AD prognosis. This chapter discusses some relevant points about the receptors involved with AD.
Caracterização sociodemográfica e clínica de pacientes oncológicos
Authors: Portella Monique Pereira , Siqueira Fernanda Duarte , Benetti Eliane Raquel Rieth , Stübe Mariléia , Cruz Cibele Thomé da , Stumm Eniva Miladi Fernandes
Published: April 2020

Objetivo: caracterizar pacientes oncológicos internados em um hospital geral com variáveis sociodemográficas e clínicas. Método: estudo transversal, descritivo, quantitativo realizado com 198 pacientes oncológicos hospitalizados nas Clínicas Médica, Cirúrgica e Oncológica, nos meses de dezembro de 2013 a julho de 2014. Os dados foram coletados por meio de Formulário de Caracterização Sociodemográfica e Clínica, analisados com o uso de estatística descritiva. Foram observados os aspectos éticos que regem uma pesquisa com pessoas, projeto de pesquisa aprovado por Comitê de Ética em Pesquisa. Resultados: dentre os participantes, 55,6% eram do sexo masculino, a maioria com mais de 50 anos de idade, 59,1% possuíam ensino fundamental incompleto, 63,6% eram católicos; 27,8% dos pacientes foram acometidos por câncer do sistema gastrintestinal, 53% com diagnóstico a menos de um ano. Conclusão: conhecer o perfil dos pacientes assistidos é importante para a equipe multiprofissional, em especial para o enfermeiro, por favorecer e subsidiar o planejamento da assistência de enfermagem.
Influência do processo de mistura de pós na preparação magistral de cápsulas de ibuprofeno
Authors: Rosa Maiane , Flores Fernanda Cramer , Beck Ruy Carlos Ruver , Adams Andréa Inês Horn , Silva Cristiane De Bona da
Published: April 2020

O objetivo do presente trabalho foi avaliar a influência do processo de mistura de pós na preparação magistral de cápsulas contendo ibuprofeno. Para a mistura dos pós foram utilizados o misturador e triturador automático e mistura manual em saco plástico. Depois de estabelecidos os tempos ótimo de mistura, cápsulas de ibuprofeno foram preparadas (3 lotes de 40 cápsulas), nas doses de 100 e 200 mg. O controle de qualidade das cápsulas foi realizado através da determinação do peso médio, doseamento e uniformidade de doses unitárias. Através dos resultados, diferenças entre os dois processos de mistura foram observadas, especialmente para a mistura de pós contendo ibuprofeno na dose de 100 mg. Os lotes obtidos pela mistura manual, neste caso, não cumpriram com as especificações em relação à uniformidade de doses. Para as cápsulas contendo ibuprofeno na dose de 200 mg os resultados foram satisfatórios.
Doenças Ocupacionais: Contexto Histórico e Realidade Da Região dos Vales/Rs
Authors: Ulguim Fernanda Oliveira , Muniz Carine , Winik Verônica
Published: April 2020

Objetivo: este artigo visa promover a reflexão, acerca dos fatores de risco para doenças e agravos à saúde dentro do ambiente de trabalho e suas implicações na sociedade. Método: serão apresentados dados, conforme notificações divulgadas pelo Informe Epidemiológico do CEREST/Vales. As informações compreendem o período de notificações registradas entre os anos de 2007 a 2010. Os resultados apresentados estão estratificados por coordenadoria, sexo, tipo de agravo, local do agravo e CBO. Resultados: observa-se que, embora a saúde do trabalhador esteja num momento de conquistas de classe, através de Leis, Portarias, Decretos, Normas Regulamentadoras e ações com foco direcionado para a prevenção, manutenção e promoção da saúde, ainda se faz necessário, aprofundar a discussão sobre o tema, pois só assim, caminharemos para a diminuição dos dilemas e paradoxos deste campo do conhecimento.
Ação curativa e protetora de compostos orgânicos e inorgânicos no controle de Microsphaera diffusa em soja
Authors: Furtado Emanueli Bizarro , Dorneles Keilor da Rosa , Dallagnol Leandro José
Published: April 2020

O objetivo do trabalho foi avaliar o efeito dos produtos acibenzolar-s-metil, fosfito de potássio, silicato de potássio e trifloxistrobina + protioconazole no controle curativo do oídio (Microsphaera diffusa) na soja. O delineamento experimental foi inteiramente casualizado, em esquema unifatorial, contendo cinco tratamentos com quatro repetições. A aplicação dos produtos foi realizada no estádio fenológico V4, no qual as plantas possuíam 5% de severidade da doença. Aos 7, 14 e 21 dias após aplicação dos tratamentos (DAA), foi avaliada a incidência e severidade da doença. O trifloxistrobina + protioconazole reduziu a incidência em 30% e a severidade em 80%, quando comparado ao controle. Também foi avaliado o efeito inibitório dos produtos na produção de conídios in vivo e na sua germinação in vitro. O trifloxistrobina + protioconazole proporcionou a maior redução na produção de conídios e na inibição da germinação. O acibenzolar-s-metil, fosfito de potássio e silicato de potássio também reduziram a germinação de conídios, mas não afetaram a produção. Com base nisso, conclui-se que, o fungicida trifloxistrobina + protioconazole reduziu a produção de conídios e inibiu sua germinação, apresentando efeito curativo e protetor contra oídio em soja e que os indutores de resistência testados, interferem na germinação do patógeno, mas sem efeito significativo na doença quando aplicados após o surgimento dos sintomas.
Caracterização e avaliação preliminar da ecotoxicidade de resíduo de indústrias de papelão
Authors: Silva Nádia da , Niemeyer Júlia Carina , Stolberg Joni
Published: April 2020

A indústria de papel e papelão é geradora de resíduos sólidos que demandam correto tratamento e disposição. O trabalho teve por objetivo caracterizar a composição de resíduos de duas empresas de papelão de Santa Catarina e avaliar sua ecotoxicidade. A caracterização foi feita com a determinação da umidade, cinzas e celulose. A ecotoxicidade foi avaliada com ensaios de fuga com minhocas (Eisenia andrei), ensaios de reprodução com colêmbolos (Folsomia candida) e com um teste de germinação e crescimento de raízes de alface (Lactuca sativa). Para as avaliações dos ensaios de toxicidade utilizou-se a ANOVA seguida dos testes de Tukey e/ou Dunnet e o teste exato de Fisher todos à p<0,05. Os Resíduos 1 e 2 apresentaram umidade de 87,23 e 60,80%, cinzas 11,18 e 55,12% e celulose 59,34 e 66,78%, respectivamente. Os ensaios de fuga e de reprodução não indicaram ecotoxicidade dos resíduos estudados para minhocas e colêmbolos quando comparados ao solo de plantio de pinus. Em relação ao crescimento de raízes, o Resíduo 1 apresentou toxicidade para as concentrações de 100, 75 e 50% do seu elutriato. Os resultados indicaram que os resíduos possuem características químicas, físicas e ecotoxicológicas que podem ser restritivas quanto a sua aplicação em solos agrícolas.
A Practical Guide to the Benefits & Barriers to Mobile Technology Integration In Social Studies
Authors: Waters Stewart , Hensley Matt
Published: April 2020

Mobile technology continues to change and evolve the way people and society function in their everyday lives. Much like the phenomenon that was the Internet 20 years ago, educators now find themselves facing increasing pressure to adapt classroom instruction to accommodate for new and
emerging technologies. This article offers practical considerations from our own classroom experiences surrounding the benefits and barriers of incorporating mobile technology in social studies instruction. We provide readers with a rationale for the use of mobile technology in social studies
classrooms, as well as general lists of benefits and barriers to using this technology in the classroom to hopefully assist educators in overcoming common fears associated with the use of mobile technology in the classroom.
Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation
Authors: Yang Hee Won , Cappell Steven D , Jaimovich Ariel , Liu Chad , Chung Mingyu , Daigh Leighton H , Pack Lindsey R , Fan Yilin , Regot Sergi , Covert Markus , Meyer Tobias
Published: April 2020

Mammalian cells typically start the cell-cycle entry program by activating cyclin-dependent protein kinase 4/6 (CDK4/6). CDK4/6 activity is clinically relevant as mutations, deletions, and amplifications that increase CDK4/6 activity contribute to the progression of many cancers. However, when CDK4/6 is activated relative to CDK2 remained incompletely understood. Here, we developed a reporter system to simultaneously monitor CDK4/6 and CDK2 activities in single cells and found that CDK4/6 activity increases rapidly before CDK2 activity gradually increases, and that CDK4/6 activity can be active after mitosis or inactive for variable time periods. Markedly, stress signals in G1 can rapidly inactivate CDK4/6 to return cells to quiescence but with reduced probability as cells approach S phase. Together, our study reveals a regulation of G1 length by temporary inactivation of CDK4/6 activity after mitosis, and a progressively increasing persistence in CDK4/6 activity that restricts cells from returning to quiescence as cells approach S phase.
Diminished responses to bodily threat and blunted interoception in suicide attempters
Authors: DeVille Danielle C , Kuplicki Rayus , Stewart Jennifer L ,   Tulsa 1000 Investigators, Aupperle Robin L , Bodurka Jerzy , Cha Yoon-Hee , Feinstein Justin , Savitz Jonathan B , Victor Teresa A , Paulus Martin P , Khalsa Sahib S
Published: April 2020

Psychological theories of suicide suggest that certain traits may reduce aversion to physical threat and increase the probability of transitioning from suicidal ideation to action. Here, we investigated whether blunted sensitivity to bodily signals is associated with suicidal action by comparing individuals with a history of attempted suicide to a matched psychiatric reference sample without suicide attempts. We examined interoceptive processing across a panel of tasks: breath-hold challenge, cold-pressor challenge, and heartbeat perception during and outside of functional magnetic resonance imaging. Suicide attempters tolerated the breath-hold and cold-pressor challenges for significantly longer and displayed lower heartbeat perception accuracy than non-attempters. These differences were mirrored by reduced activation of the mid/posterior insula during attention to heartbeat sensations. Our findings suggest that suicide attempters exhibit an ‘interoceptive numbing’ characterized by increased tolerance for aversive sensations and decreased awareness of non-aversive sensations. We conclude that blunted interoception may be implicated in suicidal behavior.
Conservation and divergence of related neuronal lineages in the Drosophila central brain
Authors: Lee Ying-Jou , Yang Ching-Po , Miyares Rosa L , Huang Yu-Fen , He Yisheng , Ren Qingzhong , Chen Hui-Min , Kawase Takashi , Ito Masayoshi , Otsuna Hideo , Sugino Ken , Aso Yoshi , Ito Kei , Lee Tzumin
Published: April 2020

Wiring a complex brain requires many neurons with intricate cell specificity, generated by a limited number of neural stem cells. Drosophila central brain lineages are a predetermined series of neurons, born in a specific order. To understand how lineage identity translates to neuron morphology, we mapped 18 Drosophila central brain lineages. While we found large aggregate differences between lineages, we also discovered shared patterns of morphological diversification. Lineage identity plus Notch-mediated sister fate govern primary neuron trajectories, whereas temporal fate diversifies terminal elaborations. Further, morphological neuron types may arise repeatedly, interspersed with other types. Despite the complexity, related lineages produce similar neuron types in comparable temporal patterns. Different stem cells even yield two identical series of dopaminergic neuron types, but with unrelated sister neurons. Together, these phenomena suggest that straightforward rules drive incredible neuronal complexity, and that large changes in morphology can result from relatively simple fating mechanisms.
Condensin I subunit Cap-G is essential for proper gene expression during the maturation of post-mitotic neurons
Authors: Hassan Amira , Araguas Rodriguez Pablo , Heidmann Stefan K , Walmsley Emma L , Aughey Gabriel N , Southall Tony D
Published: April 2020

Condensin complexes are essential for mitotic chromosome assembly and segregation during cell divisions, however, little is known about their functions in post-mitotic cells. Here we report a role for the condensin I subunit Cap-G in Drosophila neurons. We show that, despite not requiring condensin for mitotic chromosome compaction, post-mitotic neurons express Cap-G. Knockdown of Cap-G specifically in neurons (from their birth onwards) results in developmental arrest, behavioural defects, and dramatic gene expression changes, including reduced expression of a subset of neuronal genes and aberrant expression of genes that are not normally expressed in the developing brain. Knockdown of Cap-G in mature neurons results in similar phenotypes but to a lesser degree. Furthermore, we see dynamic binding of Cap-G at distinct loci in progenitor cells and differentiated neurons. Therefore, Cap-G is essential for proper gene expression in neurons and plays an important role during the early stages of neuronal development.
A highly accurate platform for clone-specific mutation discovery enables the study of active mutational processes
Authors: Carrami Eli M , Sharifzadeh Sahand , Wietek Nina C , Artibani Mara , El-Sahhar Salma , Sauka-Spengler Tatjana , Yau Christopher , Tresp Volker , Ahmed Ahmed A
Published: April 2020

Bulk whole genome sequencing (WGS) enables the analysis of tumor evolution but, because of depth limitations, can only identify old mutational events. The discovery of current mutational processes for predicting the tumor’s evolutionary trajectory requires dense sequencing of individual clones or single cells. Such studies, however, are inherently problematic because of the discovery of excessive false positive (FP) mutations when sequencing picogram quantities of DNA. Data pooling to increase the confidence in the discovered mutations, moves the discovery back in the past to a common ancestor. Here we report a robust WGS and analysis pipeline (DigiPico/MutLX) that virtually eliminates all F results while retaining an excellent proportion of true positives. Using our method, we identified, for the first time, a hyper-mutation (kataegis) event in a group of ∼30 cancer cells from a recurrent ovarian carcinoma. This was unidentifiable from the bulk WGS data. Overall, we propose DigiPico/MutLX method as a powerful framework for the identification of clone-specific variants at an unprecedented accuracy.
Comparison of settlement-era vegetation reconstructions for STEPPS and REVEALS pollen–vegetation models in the northeastern United States
Authors: Trachsel Mathias , Dawson Andria , Paciorek Christopher J. , Williams John W. , McLachlan Jason S. , Cogbill Charles V. , Foster David R. , Goring Simon J. , Jackson Stephen T. , Oswald W. Wyatt , Shuman Bryan N.
Published: April 2020

Reconstructions of prehistoric vegetation composition help establish natural baselines, variability, and trajectories of forest dynamics before and during the emergence of intensive anthropogenic land use. Pollen–vegetation models (PVMs) enable such reconstructions from fossil pollen assemblages using process-based representations of taxon-specific pollen production and dispersal. However, several PVMs and variants now exist, and the sensitivity of vegetation inferences to PVM selection, variant, and calibration domain is poorly understood. Here, we compare the reconstructions, parameter estimates, and structure of a Bayesian hierarchical PVM, STEPPS, both to observations and to REVEALS, a widely used PVM, for the pre–Euro-American settlement-era vegetation in the northeastern United States (NEUS). We also compare NEUS-based STEPPS parameter estimates to those for the upper midwestern United States (UMW). Both PVMs predict the observed macroscale patterns of vegetation composition in the NEUS; however, reconstructions of minor taxa are less accurate and predictions for some taxa differ between PVMs. These differences can be attributed to intermodel differences in structure and parameter estimates. Estimates of pollen productivity from STEPPS broadly agree with estimates produced for use in REVEALS, while comparison between pollen dispersal parameter estimates shows no significant relationship. STEPPS parameter estimates are similar between the UMW and NEUS, suggesting that STEPPS parameter estimates are transferable between floristically similar regions and scales.
Body mass index of women in Bangladesh: comparing Multiple Linear Regression and Quantile Regression
Authors: Hossain Sorif , Biswas Raaj Kishore , Hossain Md Amir
Published: April 2020

This study explored the association between socio-demographic factors and the body mass index (BMI) of women of reproductive age (15–49 years) in Bangladesh. Data from the 2014 Bangladesh Demographic and Health Survey (BDHS-14) were analysed using Multiple Linear Regression (MLR) and Quantile Regression (QR) analyses. The study sample comprised 15,636 non-pregnant women aged 15–49. The mean BMI of the women was 22.35±4.12 kg/m2. Over half (56.75%) had a BMI in the normal range (18<BMI<25 kg/m2), and 18.50%, 20.00% and 4.75% were underweight (BMI≤18 kg/m2), overweight (25≤BMI<30 kg/m2) and obese (BMI≥30 kg/m2), respectively. The results of the MLR found that age, wealth index, urban/rural place of residence, geographical division, womenʼs educational status, husbandʼs educational status, womenʼs working status and total number of children ever born were significantly (p<0.001) associated with respondents’ mean BMI. The QR results showed different associations between socio-demographic factors and mean BMI, as well as a different conditional distribution of mean BMI. Overall, the results indicated that women with uneducated husbands, with little or no education and from less-affluent households from rural areas tended to be more underweight compared with women in other groups. The inter-relationship between the study womenʼs mean BMI and associated socio-demographic factors was assessed using QR analysis to identify the most vulnerable cohorts of women in Bangladesh.
QUOTIENTS OF ÉTALE GROUPOIDS AND THE ABELIANIZATIONS OF GROUPOID C*-ALGEBRAS
Authors: KOMURA FUYUTA
Published: April 2020

In this paper, we introduce quotients of étale groupoids. Using the notion of quotients, we describe the abelianizations of groupoid C*-algebras. As another application, we obtain a simple proof that effectiveness of an étale groupoid is implied by a Cuntz–Krieger uniqueness theorem for a universal groupoid C*-algebra.
A precessing and nutating jet in OJ287
Authors: Britzen Silke , Fendt C. , Witzel G. , Qian S.-J. , Pashchenko I. N. , Kurtanidze O. , Zajacek M. , Martinez G. , Karas V. , Aller M. , Aller H. , Eckart A. , Nilsson K. , Arévalo P. , Cuadra J. , Subroweit M. , Witzel A.
Published: April 2020

We re-analyzed OJ287 in 120 Very Long Baseline Array (VLBA, MOJAVE) observations (at 15 GHz) covering the time span between Apr. 1995 and Apr. 2017. We find that the radio jet motion over the sky is consistent with a precessing and nutating jet source. The variability of the radio flux-density can be explained by Doppler beaming due to a change in the viewing angle. We suggest that part of the optical emission is due to synchrotron emission related to the jet radiation. We find a strikingly similar scaling for the timescales for precession and nutation as indicated for SS433 with a factor of roughly 50 times longer in OJ287.