bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of HZSM-5 Rich in Paired Al and Its Catalytic Performance for Propane Aromatization
Authors: Shi Dezhi , Wang Sen , Wang Hao , Wang Pengfei , Zhang Li , Qin Zhangfeng , Wang Jianguo , Zhu Huaqing , Fan Weibin
Published: June 2020

A series of HZSM-5 catalysts with similar Si/AlF mole ratio, textual properties and morphology, but different contents of AlF pairs, were synthesized by controlling the Na/Al molar ratios in the precursor gel and used for propane aromatization. It is shown that the catalyst with a Na/Al molar ratio of 0.8 in the synthetic gel possesses the highest paired AlF concentration (64.4%) and shows higher propane conversion (38.2%) and aromatics selectivity (19.7 wt.%). Propane pulse experiments, micro reactor activity estimation, Operando diffuse reflectance ultraviolet-visible (DR UV-vis) spectroscopy and Fourier Transform Infrared Spectroscopy (FTIR) analysis of coke species deposited on the catalysts provide evidence that AlF pairs in the ZSM-5 framework promote oligomerization and cyclization reactions of olefins, and then produce more aromatics. Density Functional Theory (DFT) calculations demonstrate that the cyclization of olefins and hydride transfer reaction occurring on AlF pairs in HZSM-5 zeolite show a lower free energy barrier and a higher rate constant than those on single AlF, indicating that the structure of AlF pairs in the HZSM-5 zeolite has a stronger electrostatic stabilization effect on the transition states than that of single AlF.
Bioactive Lipid Signaling in Cardiovascular Disease, Development, and Regeneration
Authors: Wasserman Aaron H. , Venkatesan Manigandan , Aguirre Aitor
Published: June 2020

Cardiovascular disease (CVD) remains a leading cause of death globally. Understanding and characterizing the biochemical context of the cardiovascular system in health and disease is a necessary preliminary step for developing novel therapeutic strategies aimed at restoring cardiovascular function. Bioactive lipids are a class of dietary-dependent, chemically heterogeneous lipids with potent biological signaling functions. They have been intensively studied for their roles in immunity, inflammation, and reproduction, among others. Recent advances in liquid chromatography-mass spectrometry techniques have revealed a staggering number of novel bioactive lipids, most of them unknown or very poorly characterized in a biological context. Some of these new bioactive lipids play important roles in cardiovascular biology, including development, inflammation, regeneration, stem cell differentiation, and regulation of cell proliferation. Identifying the lipid signaling pathways underlying these effects and uncovering their novel biological functions could pave the way for new therapeutic strategies aimed at CVD and cardiovascular regeneration.
Administration of Human Non-Diabetic Mesenchymal Stromal Cells to a Murine Model of Diabetic Fracture Repair: A Pilot Study
Authors: Watson Luke , Chen Xi Zhe , Ryan Aideen E. , Fleming Áine , Carbin Aoife , O’Flynn Lisa , Loftus Paul G. , Horan Emma , Connolly David , McDonnell Patrick , McNamara Laoise M. , O’Brien Timothy , Coleman Cynthia M.
Published: June 2020

Individuals living with type 1 diabetes mellitus may experience an increased risk of long bone fracture. These fractures are often slow to heal, resulting in delayed reunion or non-union. It is reasonable to theorize that the underlying cause of these diabetes-associated osteopathies is faulty repair dynamics as a result of compromised bone marrow progenitor cell function. Here it was hypothesized that the administration of non-diabetic, human adult bone marrow-derived mesenchymal stromal cells (MSCs) would enhance diabetic fracture healing. Human MSCs were locally introduced to femur fractures in streptozotocin-induced diabetic mice, and the quality of de novo bone was assessed eight weeks later. Biodistribution analysis demonstrated that the cells remained in situ for three days following administration. Bone bridging was evident in all animals. However, a large reparative callus was retained, indicating non-union. µCT analysis elucidated comparable callus dimensions, bone mineral density, bone volume/total volume, and volume of mature bone in all groups that received cells as compared to the saline-treated controls. Four-point bending evaluation of flexural strength, flexural modulus, and total energy to re-fracture did not indicate a statistically significant change as a result of cellular administration. An ex vivo lymphocytic proliferation recall assay indicated that the xenogeneic administration of human cells did not result in an immune response by the murine recipient. Due to this dataset, the administration of non-diabetic bone marrow-derived MSCs did not support fracture healing in this pilot study.
The Photophysical Properties of Triisopropylsilyl-ethynylpentacene—A Molecule with an Unusually Large Singlet-Triplet Energy Gap—In Solution and Solid Phases
Authors: Schaberle Fabio A. , Serpa Carlos , Arnaut Luis G. , Ward Andrew D. , Karlsson Joshua K. G. , Atahan Alparslan , Harriman Anthony
Published: June 2020

The process of singlet-exciton fission (SEF) has attracted much attention of late. One of the most popular SEF compounds is TIPS-pentacene (TIPS-P, where TIPS = triisopropylsilylethynyl) but, despite its extensive use as both a reference and building block, its photophysical properties are not so well established. In particular, the triplet state excitation energy remains uncertain. Here, we report quantitative data and spectral characterization for excited-singlet and -triplet states in dilute solution. The triplet energy is determined to be 7940 ± 1200 cm−1 on the basis of sensitization studies using time-resolved photoacoustic calorimetry. The triplet quantum yield at the limit of low concentration and low laser intensity is only ca. 1%. Self-quenching occurs at high solute concentration where the fluorescence yield and lifetime decrease markedly relative to dilute solution but we were unable to detect excimer emission by steady-state spectroscopy. Short-lived fluorescence, free from excimer emission or phosphorescence, occurs for crystals of TIPS-P, most likely from amorphous domains.
Microclimate Analysis as a Design Driver of Architecture
Authors: Graham Jonathan , Berardi Umberto , Turnbull Geoffrey , McKaye Robert
Published: June 2020

In the context of global climate change, it is increasingly important for architects to understand the effects of their interventions on indoor and outdoor thermal comfort. New microclimate analysis tools which are gaining appreciation among architects enable the assessment of different design options in terms of biometeorological parameters, such as the Universal Thermal Climate Index (UTCI) and the Outdoor Thermal Comfort Autonomy. This paper reflects on some recent experiences of an architectural design office attempting to incorporate local climatic considerations as a design driver in projects. The investigation shows that most of the available tools for advanced climatic modelling have been developed for research purposes and are not optimized for architectural and urban design; consequently, they require adaptations and modifications to extend their functionality or to achieve interoperability with software commonly used by architects. For this scope, project-specific Python scripts used to extract design-consequential information from simulation results, as well as to construct meteorological boundary conditions for microclimate simulations, are presented. This study describes the obstacles encountered while implementing microclimate analysis in an architectural office and the measures taken to overcome them. Finally, the benefits of this form of analysis are discussed.
Crystal Structure and Hirshfeld Surface Analysis of Bis(Triethanolamine)Nickel(II) Dinitrate Complex and a Revelation of Its Characteristics via Spectroscopic, Electrochemical and DFT Studies Towards a Promising Precursor for Metal Oxides Synthesis
Authors: Deeloed Wanchai , Wannapaiboon Suttipong , Pansiri Pimporn , Kumpeerakij Pornsawan , Phomphrai Khamphee , Laobuthee Apirat , Hanlumyuang Yuranan , Suramitr Songwut , Pinyou Piyanut , Wattanathana Worawat
Published: June 2020

Metal complexes with chelating ligands are known as promising precursors for the synthesis of targeted metal oxides via thermal decomposition pathways. Triethanolamine (TEA) is a versatile ligand possessing a variety of coordination modes to metal ions. Understanding the crystal structure is beneficial for the rational design of the metal complex precursors. Herein, a bis(triethanolamine)nickel (II) dinitrate (named as Ni-TEA) crystal was synthesized and thoroughly investigated. X-ray crystallography revealed that Ni(II) ions adopt a distorted octahedral geometry surrounded by two neutral TEA ligands via two N and four O coordinates. Hirshfeld surface analysis indicated the major contribution of the intermolecular hydrogen-bonding between —OH groups of TEA in the crystal packing. Moreover, several O–H stretching peaks in Fourier transformed infrared spectroscopy (FTIR) spectra emphasizes the various chemical environments of —OH groups due to the formation of the hydrogen-bonding framework. The Density-functional theory (DFT) calculation revealed the electronic properties of the crystal. Furthermore, the Ni-TEA complex is presumably useful for metal oxide synthesis via thermal decomposition at a moderate temperature (380 °C). Cyclic voltammetry indicated the possible oxidative reaction of the Ni-TEA complex at a lower potential than nickel(II) nitrate and TEA ligand, highlighting its promising utility for the synthesis of mixed valence oxides such as spinel structures.
Metal Complexes of π-Expanded Ligand (7): Syntheses, Structures and Properties of Pt(II) Complexes Containing the Isomeric 1- and 2-Alkyliminomethyl Pyrene Ligands
Authors: Luong Xuan-Dien , Nguyen Xuan-Truong
Published: June 2020

A [O,N] bidentate π-expanded ligand system, (E)-1-(n-octylimino)methylpyren-2-ol (2), was newly synthesized via a six-step synthesis from pyrene. The ligand 2 reacts with [PtCl2(PhCN)2] in chlorobenzene and the presence of a base at reflux for 2 h under the formation of (2(Pt)) complex with a yield of 70%. The molecular structure of (2(Pt)), studied by common spectroscopic methods and X-ray diffraction, shows a square planar geometry with a trans-configuration of the ligands. The molecular structure, absorption spectra, electrochemical properties, and phosphorescence characteristics of the (2(Pt)) complex are discussed, emphasizing the comparison with those of the previously reported Pt complex (1(Pt)) containing the isomeric ligands of 2, (E)-2-(n-octylimino)methylpyren-1-ol. The DFT calculations of the two Pt complexes are carried out and exhibit a clear explanation of the relationship between their physico-chemical characteristics.
The Strange Case of a Broken Periodontal Instrument Tip
Authors: Kaufmann Manuela E. , Solderer Alex , Hofer Deborah , Schmidlin Patrick R.
Published: June 2020

This case report describes a rare case of a broken periodontal probe tip and its removal. A male patient presented himself in June 2019 due to a painful tooth in the upper left quadrant. The patient elected treatment in the dental school’s student course. In October 2019, in preparation for full-mouth rehabilitation, a complete diagnostic status was performed, including radiographs. In this context, a metal-dense fragment was identified in the apical region of the (missing) tooth 45. It was diagnosed as the broken tip of a periodontal probe (type AE P OWB). Since a PCP-12 probe is generally used in-house, iatrogenic damage during the initial examination or student course could be excluded a priori. The patient was not able to remember any treatment that could be associated with the instrument’s breaking. Since the probe fragment was palpable and a translocation could not be precluded, the patient agreed to its removal under local anesthesia, after a cone-beam CT. This article describes and discusses this particular case, with special emphasis on iatrogenic instrument fractures and their removal.
State Ownership and Risk-Taking Behavior: An Empirical Approach to Get Better Profitability, Investment, and Trading Strategies for Listed Corporates in Vietnam
Authors: Nguyen Tran Thai Ha , Moslehpour Massoud , Vo Thi Thuy Van , Wong Wing-Keung
Published: June 2020

Corporate risk-taking behavior and investment is a crucial factor in order to seek higher profits and a better trading strategy. Competitive advantage and innovation, while maintaining profitability and state ownership, are considered as crucial resources. Furthermore, it is essential to connect the short-term and long-term business and investment objectives plus stakeholder’s expectations to corporate sustainability and development. This connection is especially important in the context of transforming economies and getting better trading strategies. This study estimates the relationship between state ownership, profitability, corporate risk-taking behavior, and investment in Vietnam by using Generalized Method of Moments (GMM) methods. Using the data of 501 listed non-financial corporates during the period 2007–2015 from Ho Chi Minh City and Hanoi Stock Exchanges, we find that profitability is determined as a factor to reduce corporate risk-taking acceptance caused by the chances of entrenchment. Meanwhile, the impact of state ownership on the risk appetite of corporate has a non-linear effect. In particular, state ownership reduces corporate risk-taking behavior and investment but yet increases the risk-taking behavior and investment when the state ownership rate exceeds a threshold. One the one hand, this implies that the low level of state ownership not only prevents risk-taking behavior and investment but also results in more severe agency problems, causing unsustainability due to the imbalance of interests among various stakeholders. On the other hand, a dominant role of state ownership concentration causes a boost in corporate risk-taking decision-making in investment and trading strategy, leveraging the connection of significant external resources to deal with uncertain problems. The study contributes to existing theories of corporate governance in the context of a socialist-oriented market.
Special Educational Needs, Distance Learning, Inclusion and COVID-19
Authors: Petretto Donatella Rita , Masala Ilaria , Masala Carmelo
Published: June 2020

In the last two months, school closure has been one of the more used worldwide “not-pharmacological mitigation strategies” to prevent and limit infection from COVID-19, and to delay the outbreak’s peak [...]
Fluency: Deep Roots in Reading Instruction
Authors: Rupley William H. , Nichols William Dee , Rasinski Timothy V. , Paige David
Published: June 2020

Over the past two decades, reading fluency has been increasingly recognized as an important instructional variable for success in reading. Yet, this has not always been the case. This article presents a historical review of the nature and role of fluency instruction in the United States. The roots of oral reading fluency began in an age when texts and other forms of entertainment and information were limited. Historically, in America, oral reading was the predominant means for conveying ideas and passing the time at home with the family. In the 1800s, American education’s primary method of instruction emphasized the need for being able to read aloud with expression and fluency, in order to hold the listeners’ attention and convey information. As texts and other forms of information became more available, oral reading became deemphasized, and silent reading was viewed as a better approach to developing readers’ comprehension at the cost of fluency development. With continued research and national reports that indicate the significant contributions of oral reading fluency to reading comprehension and academic proficiency, it is clear that the roots of oral reading run deep, and that fluent reading development is important to learners’ academic achievement and reading comprehension.
Engineering Metamaterials: Present and Future
Authors: Maslovski Stanislav
Published: June 2020

A couple of decades have passed since the advent of electromagnetic metamaterials [...]
Numerical Analysis of Space Charge Behavior and Transient Electric Field under Polarity Reversal of HVDC Extruded Cable
Authors: Kim Sun-Jin , Lee Bang-Wook
Published: June 2020

The superimposed transient electric field generated by polarity reversal causes severe stress to the high-voltage direct current (HVDC) cable insulation. Especially for polymeric insulation materials, space charge accumulation is prominent, which strengthens local electric field intensity. In order to avoid the risk of dielectric breakdown resulting from an intensified electric field caused by space charge behavior, several numerical analyses have been conducted using the Bipolar Charge Transport (BCT) model. However, these studies have only considered a unidirectional electric field assuming only steady state operating conditions, and there are few works that have analyzed space charge behavior during transient states, especially for the polarity reversal period. In order to analyze the charge behavior under polarity reversal, it is necessary to establish the boundary condition considering the direction and intensity of the field. Therefore, in this paper, we proposed a modified model connecting the steady state to the polarity reversal state, and the transient electric field was investigated depending on the electric potential zero duration. Since space charge behavior is influenced by temperature, different load currents were considered. From the simulation results, it was observed that the capacitive field was dominant on the electric field distribution during the polarity reversal. In addition, the long electric potential zero duration and high load currents could contribute to form a homo-charge at the conductor within the time of polarity reversal, resulting in a noticeable decrease in the maximum electric field intensity.
Ultra-Short-Term Photovoltaic Power Prediction Model Based on the Localized Emotion Reconstruction Emotional Neural Network
Authors: Wang Yufei , Zhu Li , Xue Hua
Published: June 2020

Due to the intermittency and randomness of photovoltaic (PV) power, the PV power prediction accuracy of the traditional data-driven prediction models is difficult to improve. A prediction model based on the localized emotion reconstruction emotional neural network (LERENN) is proposed, which is motivated by chaos theory and the neuropsychological theory of emotion. Firstly, the chaotic nonlinear dynamics approach is used to draw the hidden characteristics of PV power time series, and the single-step cyclic rolling localized prediction mechanism is derived. Secondly, in order to establish the correlation between the prediction model and the specific characteristics of PV power time series, the extended signal and emotional parameters are reconstructed with a relatively certain local basis. Finally, the proposed prediction model is trained and tested for single-step and three-step prediction using the actual measured data. Compared with the prediction model based on the long short-term memory (LSTM) neural network, limbic-based artificial emotional neural network (LiAENN), the back propagation neural network (BPNN), and the persistence model (PM), numerical results show that the proposed prediction model achieves better accuracy and better detection of ramp events for different weather conditions when only using PV power data.
Global View of Biofuel Butanol and Economics of Its Production by Fermentation from Sweet Sorghum Bagasse, Food Waste, and Yellow Top Presscake: Application of Novel Technologies
Authors: Qureshi N. , Lin X. , Liu S. , Saha B. C. , Mariano A. P. , Polaina J. , Ezeji T. C. , Friedl A. , Maddox I. S. , Klasson K. T. , Dien B. S. , Singh V.
Published: June 2020

Worldwide, there are various feedstocks such as straws, corn stover, sugarcane bagasse, sweet sorghum bagasse (SSB), grasses, leaves, whey permeate, household organic waste, and food waste (FW) that can be converted to valuable biofuels such as butanol. For the present studies, an economic analysis was performed to compare butanol production from three feedstocks (SSB; FW; and yellow top presscake, YTP or YT) using a standard process and an advanced integrated process design. The total plant capacity was set at 170,000–171,000 metric tons of total acetone butanol ethanol (ABE) per year (99,300 tons of just butanol per year). Butanol production from SSB typically requires pretreatment, separate hydrolysis, fermentation, and product recovery (SHFR). An advanced process was developed in which the last three steps were combined into a single unit operation for simultaneous saccharification, fermentation, and recovery (SSFR). For the SHFR and SSFR plants, the total capital investments were estimated as $213.72 × 106 and $198.16 × 106, respectively. It was further estimated that the minimum butanol selling price (using SSB as a feedstock) for the two processes were $1.14/kg and $1.05/kg. Therefore, SSFR lowered the production cost markedly compared to that of the base case. Butanol made using FW had an estimated minimum selling price of only $0.42/kg. This low selling price is because the FW to butanol process does not require pretreatment, hydrolysis, and cellulolytic enzymes. For this plant, the total capital investment was projected to be $107.26 × 106. The butanol selling price using YTP as a feedstock was at $0.73/kg and $0.79/kg with total capital investments for SSFR and SHFR of $122.58 × 106 and $132.21 × 106, respectively. In the Results and Discussion section, the availability of different feedstocks in various countries such as Brazil, the European Union, New Zealand, Denmark, and the United States are discussed. Additionally, the use of various microbial strains and product recovery technologies are also discussed.
Toxic Elements and Mineral Content of Different Tissues of Endemic Edible Snails (Helix vladika and H. secernenda) of Montenegro
Authors: Vukašinović-Pešić Vesna , Pilarczyk Bogumiła , Miller Tymoteusz , Rajkowska-Myśliwiec Monika , Podlasińska Joanna , Tomza-Marciniak Agnieszka , Blagojević Nada , Trubljanin Nevzeta , Zawal Andrzej , Pešić Vladimir
Published: June 2020

The objective of the present study is to determine the differences between the mineral content of various organs of Helix vladika and H. secernenda, the two most abundant edible snail species in Montenegro. The bioaccumulation of 12 examined elements (zinc, manganese, copper, aluminum, cadmium, lead, nickel, iron, chromium, lithium, selenium and mercury) was determined in the hepatopancreas, albumen gland, digestive tract, reproductive system, mantle, foot and shell from three sampling sites (Biogradska Gora, Nikšić and Malesija). The examined populations of H. vladika and H. secernenda showed a significant difference in their lithium and selenium contents. The levels of the most examined metals (Zn, Mn, Cu, Al, Cd, Pb, Se and Hg) varied significantly among organs. The digestive tract and hepatopancreas tend to bioaccumulate selenium and cadmium. The general mean concentration of cadmium in the examined snail tissues exceeded the maximum allowable level at the Biogradska Gora and Malesija sites. Therefore, the use of the Montenegrin edible snails collected from the wilderness for human consumption seems to be limited by their higher bioaccumulation capacity for toxic elements such as cadmium.
A Review of Environment Effects on Nitrate Accumulation in Leafy Vegetables Grown in Controlled Environments
Authors: Bian Zhonghua , Wang Yu , Zhang Xiaoyan , Li Tao , Grundy Steven , Yang Qichang , Cheng Ruifeng
Published: June 2020

Excessive accumulation of nitrates in vegetables is a common issue that poses a potential threat to human health. The absorption, translocation, and assimilation of nitrates in vegetables are tightly regulated by the interaction of internal cues (expression of related genes and enzyme activities) and external environmental factors. In addition to global food security, food nutritional quality is recognized as being of strategic importance by most governments and other agencies. Therefore, the identification and development of sustainable, innovative, and inexpensive approaches for increasing vegetable production and concomitantly reducing nitrate concentration are extremely important. Under controlled environmental conditions, optimal fertilizer/nutrient element management and environmental regulation play vital roles in producing vegetables with low nitrate content. In this review, we present some of the recent findings concerning the effects of environmental factors (e.g., light, temperature, and CO2) and fertilizer/nutrient solution management strategies on nitrate reduction in vegetables grown under controlled environments and discuss the possible molecular mechanisms. We also highlight several perspectives for future research to optimize the yield and nutrition quality of leafy vegetables grown in controlled environments.
Chicken Egg Proteins and Derived Peptides with Antioxidant Properties
Authors: Benedé Sara , Molina Elena
Published: June 2020

In addition to their high nutritional value, some chicken egg proteins and derivatives such as protein hydrolysates, peptides and amino acids show antioxidant properties which make them prominent candidates for the development of functional foods, drawing attention to both the food and biopharmaceutical industries. This review summarizes current knowledge on antioxidant activity of chicken egg proteins and their derived peptides. Some egg proteins such as ovalbumin, ovotransferrin and lysozyme from egg white or phosvitin from yolk have shown antioxidant properties, although derived peptides have higher bioactive potential. The main process for obtaining egg bioactive peptides is enzymatic hydrolysis of its proteins using enzymes and/or processing technologies such as heating, sonication or high-intensity-pulsed electric field. Different in vitro assays such as determination of reducing power, DPPH and ABTS radical-scavenging activity tests or oxygen radical absorbance capacity assay have been used to evaluate the diverse antioxidant mechanisms of proteins and peptides. Similarly, different cell lines and animal models including zebrafish, mice and rats have also been used. In summary, this review collects all the knowledge described so far regarding egg proteins and derived peptides with antioxidant functions.
Date Seeds as a Natural Source of Dietary Fibers to Improve Texture and Sensory Properties of Wheat Bread
Authors: Bouaziz Fatma , Ben Abdeddayem Amal , Koubaa Mohamed , Ellouz Ghorbel Raoudha , Ellouz Chaabouni Semia
Published: June 2020

The aim of this work was to investigate the effect of date seed water-soluble polysaccharides (DSP) and hemicellulose (DSH) as dietary fiber sources in enhancing the wheat bread’s quality. DSP and DSH were extracted from the three date seed varieties Deglet Nour, Ghars Souf, and Allig. The extraction yields ranged from 3.8% to 6.14% and from 13.29% to 18.8%, for DSP and DSH, respectively. DSP and DSH showed interesting functional properties and were incorporated at 0.5% and 0.75% (w/w) in wheat flour with low bread-making quality (FLBM). The results showed that the addition of 0.75% DSH significantly improved the alveograph profile of the dough, and in a more efficient way than that of DSP. Furthermore, bread evaluation revealed that the addition of DSH considerably improved the volume (by 24.22%) and the texture profile of bread (decrease of the hardness and chewiness by 41.54% and 33.81%, respectively), compared to control bread (prepared with FLBM). A sensory analysis showed that the better overall acceptability was found for bread supplemented with DSH. Results in this work demonstrate that hemicellulose fraction extracted from date seeds (DSH) and added with a level of 0.75% to FLBM represents the component that improved bread quality the best.
Could the Heat Shock Proteins 70 Family Members Exacerbate the Immune Response in Multiple Sclerosis? An in Silico Study
Authors: Chiricosta Luigi , Gugliandolo Agnese , Bramanti Placido , Mazzon Emanuela
Published: June 2020

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system. It represents one of the main causes of neurological disability in young people. In MS, the autoimmune response is directed against myelin antigens but other possible bio-molecular markers are investigated. The aim of this work was, through an in silico study, the evaluation of the transcriptional modifications between healthy subjects and MS patients in six brain areas (corpus callosum, hippocampus, internal capsule, optic chiasm, frontal and parietal cortex) in order to identify genes representative of the disease. Our results show the upregulation of the Heat Shock Proteins (HSPs) HSPA1A, HSPA1B, HSPA7, HSPA6, HSPH1 and HSPA4L of the HSP70 family, among which HSPA1A and HSPA1B are upregulated in all the brain areas. HSP70s are molecular chaperones indispensable for protein folding, recently associated with immune system maintenance. The little overexpression of the HSPs protects the cells from stress but extreme upregulation can contribute to the MS pathogenesis. We also investigated the genes involved in the immune system that result in overall upregulation in the corpus callosum, hippocampus, internal capsule, optic chiasm and are absent in the cortex. Interestingly, the genes of the immune system and the HSP70s have comparable levels of expression.
Static Survey as Geological Engineering Method Verification of DSM Column Formation
Authors: Jendruś Rafał , Stawiarski Arkadiusz , Pach Grzegorz , Pierzyna Piotr
Published: June 2020

The state-of-the-art methods for verifying the correctness of ground improvement performed using the DSM (Deep Soil Mixing) technology are largely focused on the selection of adequate factors impacting the achievement of a correct compressive strength fc [MPa] of the column core, which ensures the transfer of stress from the designed structures to the subsoil. In view of the operation of each of the columns, it is equally significant to ensure that their bases are located in load-bearing soil at the entire area of the improvement, without the need to perform many costly subsoil surveys. Based on the complementary soil investigation results and parameters obtained during deep soil mixing from an automatic logger installed on the drilling machine, a method of comparing the rotary drive pressure (working pressure) PKDK [bar] and the cone resistance qc [MPa] of the CPTU static probe (Cone Penetration Test Unit with Pore Pressure Measurement) was developed along with the method to interpret the results in the context of the correctness of the ground improvement on the construction site analyzed in this paper.
A Mixed Methods Evaluation of a Randomized Control Trial to Evaluate the Effectiveness of the Pure Prairie Living Program in Type 2 Diabetes Participants
Authors: Archundia-Herrera M. Carolina , Subhan Fatheema B. , Sakowsky Cathy , Watkins Karen , Chan Catherine B.
Published: June 2020

The primary objective of this randomized control trial was to evaluate the effectiveness of the Pure Prairie Living Program (PPLP) in a primary care setting. Adults with type 2 diabetes were randomized into intervention (PPLP, n = 25) and wait-listed controls (CON, n = 24). The PPLP group participated in education sessions. The intervention yielded no significant within-group changes in HbA1c at three-month (−0.04 (−0.27 to 0.17) and −0.15 (−0.38 to 0.08)) or six-month (−0.09 (−0.41 to 0.22) and 0.06 (−0.26 to 0.38)) follow ups in either CON or PPLP groups, respectively. Dietary adherence scores improved in the PPLP group (p < 0.05) at three and six months but were not different in the between-group comparison. No changes in diabetes self-efficacy scores were detected. In the qualitative analysis, participants described the program as clear and easy to understand. Knowledge acquired influenced their everyday decision making but participants faced barriers that prevented them from fully applying what they learned. Healthcare professionals enjoyed delivering the program but described the “back-stage” workload as detrimental. In conclusion, while some positive effects of the PPLP intervention were observed, they were not comparable to those previously attained by our group in an academic setting or to what the guidelines recommend, which reflects the challenge of translating lifestyle intervention to real-world settings.
Increased Risk of COVID-19-Related Deaths among General Practitioners in Italy
Authors: Modenese Alberto , Gobba Fabriziomaria
Published: June 2020

To date, data on COVID-19-related death cases among physicians from different medical specialties are incomplete and scattered. In Italy, available data highlight that general practitioners (GPs) are, apparently, the most heavily affected group. Indeed, they currently represent 44.1% of the total COVID-19 related death cases occurred among physicians, whereas they constitute about 15% of the total number of doctors. This high proportion is most likely the consequence of a work-related contagion happening especially during the first weeks of the epidemic, and persisting also in the following weeks, after the national lockdown. There are various reasons for these higher contagion rates: GPs perform a lot of medical examinations daily, usually in close contact with patients. Especially at the beginning of the epidemic, GPs might have had scant information on the specific safety procedures for the prevention of SARS-CoV-2 transmission (e.g., there was limited knowledge on the possibility of contagions deriving from asymptomatic patients) and, moreover, the availability of personal protective equipment was insufficient. Furthermore, the risk of infection is highly increased by the virus’ characteristics, like its survival for several hours/days on different surfaces and its persistence in the air after an aerosolization process, with possibilities to be transmitted over distances longer than two meters. Following these observations, and considering the high cost in term of GPs’ lives, the COVID-19 pandemic will probably revolutionize the approach to patients in general practice. Clear and effective guidelines are absolutely and urgently needed for the refinement of adequate measures to prevent SARS-CoV-2 infections among GPs.
Using the Integrated Kano–RIPA Model to Explore Teaching Quality of Physical Education Programs in Taiwan
Authors: Ku Gordon Chih-Ming , Shang I-Wei
Published: June 2020

The purpose of this study was to apply the Kano model and revised importance–performance analysis (RIPA) to explore the teaching quality of physical education programs at Taiwanese universities. Random sampling was used to select universities from the north, south, central, and east areas of Taiwan. The questionnaire developed by the researcher included 20 items within four subscales. A total of 970 students participated in this study. A combination of the Kano model and RIPA was used for analysis. The results indicate that the item “physical education teachers have cordial attitudes toward instructions” fell into the “keep up the good work” designation of RIPA and the fourth quadrant of the Kano model. A patient and cordial attitude towards students can, therefore, be considered an important quality factor for physical education programs. Teacher–student relationships should, therefore, form a priority for physical education teachers looking to increase student satisfaction and optimize their programs.
A Comparison of Infection Venues of COVID-19 Case Clusters in Northeast China
Authors: Zhao Pengcheng , Zhang Nan , Li Yuguo
Published: June 2020

The world has been suffering from the COVID-19 pandemic since late 2019. In this study, we compared various types of infection locations in which COVID-19 cases clustered, based on the data from three adjacent provinces in Northeast China. The collected data include all officially reported cases in this area until 8 March 2020. We explored the associations between the cases and the frequency of infection locations. The COVID-19 epidemic situation was worse in Heilongjiang Province than in Liaoning and Jilin Provinces. Most clustered cases occurred in individual families and/or between relatives. The transmission in public venues served as a hub for transmitting the disease to other families and results in new clusters. The public transport spread the infection over long distances by transporting infected individuals, and most infections did not seem to occur within vehicles. This field study shows the effect of indoor environments on SARS-CoV-2 transmission and our data may be useful in developing guidance for future disease prevention and control.
Distress and Resilience in the Days of COVID-19: Comparing Two Ethnicities
Authors: Kimhi Shaul , Eshel Yohanan , Marciano Hadas , Adini Bruria
Published: June 2020

The COVID-19 pandemic is an ongoing epidemic of coronavirus disease, caused by severe acute respiratory syndrome, which has spread recently worldwide. Efforts to prevent the virus from spreading include travel restrictions, lockdowns as well as national or regional quarantines throughout the international community. The major negative psychological outcome of the COVID-19 pandemic is the anxiety caused by it. The aim of the present study was to examine the level of concern and the contributions of modes of resilience, well-being and demographic attributes towards decreasing or enhancing anxiety and depression among two samples: Israeli Jews (majority group) and Israeli Arabs (minority group). These random samples included 605 Jews and 156 Arabs who participated in an internet survey. A previous study, which has been conducted in the context of terror attacks, has shown that compared to Israeli Jews, Israeli Arabs expressed a higher level of fear of war and lower levels of resilience supporting personality attributes. The results of the current study indicated a similar pattern that emerged in the context of the COVID-19 pandemic: the Israeli Arabs reported a higher level of distress and a lower level of resilience and well-being.
Indigenous Oral Health Inequalities at an International Level: A Commentary
Authors: Jamieson Lisa , Haag Dandara , Schuch Helena , Kapellas Kostas , Arantes Rui , Thomson W. Murray
Published: June 2020

Oral health inequalities reflect social injustice. This is because oral health simultaneously reflects material circumstances, access to health services and inequities across the life course. Oral health inequalities between Indigenous and non-Indigenous populations are among the largest in the world. This paper provides a critical commentary on Indigenous oral health inequalities at an international level based on existing literature and policies. We include the role of systematic and institutionalized racism and how this enables the persistence and flourishing of Indigenous oral health inequalities. We discuss theoretical frameworks—including Shiffman and Smith’s Political Power Framework—that underpin the power constructs that contribute to those. This theory posits that power is exercised in four ways: (i) the power of ideas; (ii) the power of the issue; (iii) the power of the actors; and (iv) the power of the political context. We will demonstrate, using examples of Indigenous oral health inequalities from several countries, how intervening at key leverage points, acting simultaneously on multiple subsystems and counteracting the social determinants of health are crucial strategies for ameliorating Indigenous oral health inequalities at a global level.
Prevalence of Traumatic Experiences in South Korean Adults
Authors: Kim Sunah , Kim Go-Un , Park Suin
Published: June 2020

Although a variety of traumatic experiences can impact health over the lifetime, little is known about the prevalence of such experiences in South Korea. The purpose of this study was to examine the frequencies of traumatic experiences and their differences by gender and age. South Korean adults (N = 3000) aged 19–65 years completed a self-report survey assessing childhood and adulthood trauma and sociodemographic characteristics. Overall, 79.5% of the participants reported at least one traumatic experience in adulthood. Unemployment or job loss and academic or work difficulties were commonly reported. The most distressing adulthood trauma was the unexpected death of a loved one, followed by diseases in loved ones. Childhood trauma was higher in males than in females. In males, childhood trauma was higher at a younger age, but in females, it was higher at an older age. Adulthood trauma was higher in females than in males and at older ages for both males and females. The current findings demonstrate the differences in traumatic experiences by gender and age in the South Korean general population. These results could help improve assessment of and targeted intervention for psychological trauma through trauma-informed strategies in public health practice.
Vaya Con Dios: The Influence of Religious Constructs on Stressors around the Migration Process and U.S. Lived Experiences among Latina/o Immigrants
Authors: Moreno Oswaldo , Ortiz Miriam , Fuentes Lisa , Garcia Dina , Leon-Perez Gabriela
Published: June 2020

This qualitative study explores the role of religious practices on the migration process and the U.S. lived experiences of Latina/o immigrants. We conducted semi-structured interviews with 20 Latino/a immigrant adults living in a southern state of the United States. Interviews focused on participants’ migration experiences, religious constructs, and stress responses. Results revealed that religious practices provided strength, well-being, and positive life outlook during the migration process. After migration, religious practices also assisted participants in creating a sense of community/family, as well as provided financial and social support during difficult times. Recommendations for future interdisciplinary research and for practitioners are discussed for individuals working with Latinx and immigrant populations.
Predictive Factors of Cyberbullying Perpetration amongst Spanish Adolescents
Authors: Yudes Carolina , Rey Lourdes , Extremera Natalio
Published: June 2020

(1) Cyberbullying has gained increased attention from society and researchers due both to its negative psychosocial consequences and the problems that have risen relating to the misuse of technology. Despite the growing number of scientific studies, most research has focused on victims of cyberbullying rather than on the cyberbullies. This study examines the predictive value of personal resources (emotional intelligence, gratitude, and core self-evaluations) and risk factors (cybervictimization, problematic Internet use), and parental control in online activities on adolescents’ involvement in cyberbullying perpetration. (2) A total of 2039 Spanish adolescents between 12 and 18 years of age took part in this research (53.9% females). (3) Twenty-two percent of the sample was engaged in cyberbullying behaviors (more male adolescents). Insults and online social exclusion were the most frequent types of cyberbullying perpetration. Age, cybervictimization, problematic Internet use, and deficits in the use and regulation of emotions were the best predictors of cyberbullying perpetration. (4) Cyberbullying is a social reality in which personal and family variables converge on a particularly vulnerable age group. Our findings suggest that both well-known predictors of cyberbullying (cybervictimization and problematic Internet use) along with others less studied dimensions (i.e., emotional abilities) need to be taken into account in future school-based interventions aimed to prevent cyberbullying perpetration.
Effects of Job Content and Physical Activity on Body Mass Index among Obese Managers of the Mexican Manufacturing Industry
Authors: Armenta-Hernandez Oziely Daniela , Maldonado-Macias Aidé Aracely , Ortiz Solís Margarita , Serrano-Rosa Miguel Ángel , Baez-López Yolanda Angélica , Hernández-Arellano Juan Luis
Published: June 2020

Mental health disorders resulting from work stressors are increasing in the Mexican manufacturing industry and worldwide. Managerial positions in these contexts are highly stressful, and although physical activity may reduce the negative effects of work stress, the relationships between these two aspects regarding their effects on the body mass index (BMI) of obese managers are scarcely studied. This article aims to study such relationships by using the Job Content Questionnaire (JCQ) dimensions with the Baecke’s physical activity questionnaire dimensions and analyzing their effects on the BMI. A sample of 255 managers from the Mexican industry, with a (BMI > 30) participated by answering the surveys and providing their weight, their height, and certain sociodemographic information. The research hypotheses were tested using WarpPLS® 6.0 for structural equation modeling. The results for three models featuring acceptable reliability to estimate the direct, indirect, and total effects are presented. The first model showed a medium explanatory power, the variable of job decision-making authority having the greatest direct effect on BMI. The second model showed a medium explanatory power, and the variable of physical activity during leisure-time observed the unique direct effect on BMI. Finally, although the integrating model showed a small explanatory power, both work stress and the physical activity exerted observed direct effects on BMI reduction.
Implementation of a Multi-Component School Lunch Environmental Change Intervention to Improve Child Fruit and Vegetable Intake: A Mixed-Methods Study
Authors: Hamdi Nader , Ellison Brenna , McCaffrey Jennifer , Metcalfe Jessica Jarick , Hoffman Ashley , Haywood Pamela , Prescott Melissa Pflugh
Published: June 2020

Nudge interventions are widely used to promote health in schools, yet implementation metrics are seldom used to understand intervention outcomes. A multi-component intervention consisting of cafeteria decorations, creative names, social norming taste tests, and flavor station components was implemented in three rural elementary school cafeterias by school nutrition services (SNS) and extension staff. Selection and consumption of fruits and vegetables at lunch were measured through monthly plate waste assessments over eight months (n = 1255 trays). Interviews were conducted with SNS staff (n = 3) upon completion of the intervention to assess implementation outcomes using validated acceptability and feasibility metrics. Consumption findings were generally inconsistent across schools and time points, yet fruit consumption increased at School 1 (p < 0.05) during the taste test and flavor station intervention months and School 2 (p < 0.001) during the creative names intervention months compared to baseline. Odds of selecting a vegetable at School 3 were three times higher than baseline during the taste test intervention months (odds ratio (OR), 3.0; 95% confidence interval (CI), 1.3–6.5). Cafeteria decorations and taste tests had higher reported implementation metrics for acceptability and feasibility than other interventions. Thematic analysis underscored the facilitating role of extension support, as well as systems factors, which served as facilitators and barriers across schools and interventions. These findings suggest that nudge interventions are a promising strategy to improve vegetable selection and fruit consumption in school meal programs.