bluuebunny/crossref_metadata_2025 huggingface dataset:
Can I Be Frank with You?
Authors: Crookston Cameron
Published: March 2021

When Fox 21 Television Studios announced that Laverne Cox would play the role of Frank N. Furter in their 2016 The Rocky Horror Picture Show: Let’s Do the Time Warp Again, most public response circled around how Cox’s visible political identity as a trans woman spoke to the problematic nature of Rocky Horror’s language and dated identity politics. Released in 1975, Richard O’Brien and Jim Sharman’s The Rocky Horror Picture Show has been a touchstone of queer popular culture for more than forty years. Rocky Horror is constructed as a self- conscious pastiche of multiple cultural moments and queer coded pieces of popular culture; Gothic literature, classic Hollywood film, science fiction B movies, Glam Rock, and drag all mingle in the queer cultural collage that makes up the show’s dramaturgy. As such, the scope of Rocky Horror serves as a kind of performative queer archive, collecting and performing generations of queer culture. However, in addition to offering a dense collection of queer cultural artifacts, Rocky Horror has also inherited many of the complicated representational aspects of its sources, such as the racist coding and simultaneous racial erasure of Gothic and horror conventions as well as rapidly changing and often conflicted trans identity politics of the mid- twentieth century. These problematic appropriations and omissions become all the more salient in light of Cox’s 2016 performance. In this article, Crookston examines how Rocky Horror has functioned as a performative queer cultural archive and how Danny Ortega’s remake, starring Cox, challenges, complicates, and excavates O’Brien’s original historiographic dramaturgy.
Queer Militarism?!
Authors: Spade Dean , Belkin Aaron
Published: March 2021

Does advocating for queer and trans people to serve in the US military move the struggle for queer and trans justice forward toward liberation by improving the lives of queer and trans soldiers and increasing societal acceptance of queer and trans people? Or does it legitimize US military imperialism and increase the likelihood of more queer and trans people being abused and traumatized in the US military? This article consists of a conversation between Aaron Belkin, director of the Palm Center, who has spent decades advocating for queer and trans military inclusion, and Dean Spade, a trans racial- and- economic- justice–focused activist and scholar who opposes military inclusion advocacy. The conversation examines fundamental debates about the possibilities and limits of legal equality for marginalized and stigmatized groups, drawing on critical race theory, women of color feminisms, anticolonial critique, and competing theories of queer and trans liberation work.
Ψηφιακός γραμματισμός στη δευτεροβάθμια εκπαίδευση
Authors: Βαρδαλάχου Ευαγγελία
Published: March 2021

Η παρούσα έρευνα αποτελεί μια εκπαιδευτική έρευνα δράσης με μαθητές της Δευτεροβάθμιας Εκπαίδευσης και σκοπός της είναι η διερεύνηση της βελτίωσης του επιπέδου των μαθητών όσον αφορά τον γλωσσικό και ψηφιακό γραμματισμό τους, με τη δημιουργική αξιοποίηση των Τεχνολογιών της Πληροφορίας και της Επικοινωνίας. Συγκεκριμένα, τα ερευνητικά ερωτήματα είναι: Μέσω των προτεινόμενων παρεμβάσεων, θα βελτιωθεί το επίπεδο των μαθητών στις γλωσσικές δεξιότητες ώστε να οδηγηθούν σταδιακά στο γλωσσικό εγγραμματισμό σύμφωνα με τις απαιτήσεις της σύγχρονης κοινωνίας; Οι προτεινόμενες δράσεις θα κινητοποιήσουν τους μαθητές να αξιοποιήσουν δημιουργικά τις ΤΠΕ ώστε να αλλάξει η σχέση τους με τον υπολογιστή και να αποκτήσουν τις απαραίτητες ψηφιακές δεξιότητες του 21ου αιώνα; Οι μαθητές, στο πλαίσιο της παρούσας έρευνας, δημιουργούν πολυτροπικό περιεχόμενο για σχολικό διαδικτυακό περιοδικό μετά από μελέτη πηγών, αποκωδικοποίηση και συγγραφή πρωτότυπων άρθρων. Κατά τη διάρκεια της δράσης, εφαρμόζεται συνεργατική, διαφοροποιημένη αλλά και εξατομικευμένη διδασκαλία με Τ.Π.Ε. Η παρουσίαση του περιοδικού σε ψηφιακή έκδοση πραγματοποιήθηκε με τη βοήθεια της πλατφόρμας issuu αλλά και με τη βοήθεια της πλατφόρμας Joomla. Χρησιμοποιήθηκαν ποικίλες μέθοδοι συλλογής δεδομένων όπως: το Ημερολόγιο, τα ερωτηματολόγια, η παρατήρηση, η βιντεοσκόπηση, οι εκθέσεις μαθητών σχετικά με τη δράση, η συνέντευξη και οι δημιουργίες των μαθητών. Η ανάλυση των δεδομένων στηρίζεται κατά κύριο λόγο στην ποιοτική ανάλυση του περιεχομένου, στη μέθοδο της τριγωνοποίησης και στη χρήση εργαλείων περιγραφικής στατιστικής. Τα αποτελέσματα της έρευνας είναι τόσο ενθαρρυντικά, ώστε δύνανται να χρησιμοποιηθούν ως πρόταση στο Υπουργείο Παιδείας για συνδιδασκαλία Γλώσσας και Πληροφορικής στο πρόγραμμα σπουδών του Γυμνασίου.
Οι παραδοσιακές διαδρομές μετακίνησης των ζώων και ο ρόλος τους στην οικολογία του λιβαδικού τοπίου
Authors: Καψάλης Δημήτριος
Published: March 2021

Η μετακινούμενη κτηνοτροφία αποτελεί ένα παραδοσιακό κτηνοτροφικό σύστημα προσαρμοσμένο στις εποχικές μεταβολές του κλίματος, αλλά και της διαθέσιμης βοσκήσιμης ύλης και αποτελεί έναν από τους πιο χαρακτηριστικούς τρόπους εκτροφής των ζώων σε όλη τη λεκάνη της Μεσογείου. Μέσω αυτής της διδακτορικής διατριβής, έγινε προσπάθεια να αποτυπωθεί ο ρόλος των μετακινούμενων κοπαδιών στην οικολογία του τοπίου και ειδικότερα του λιβαδικού. Συγκεκριμένα, σκοπός της έρευνας ήταν να αποτυπωθεί το δίκτυο των μετακινούμενων κτηνοτρόφων της Θεσσαλίας προς τη Βόρεια Ελλάδα και το πως επηρεάστηκε διαχρονικά το τοπίο από αυτήν τη δραστηριότητα. Τις τελευταίες δεκαετίες έχει καταγραφεί σημαντική μείωση της μετακινούμενης κτηνοτροφίας και οι διαδρομές αυτές εγκαταλείπονται. Για την επίτευξη του σκοπού, αναζητήθηκαν οι παραδοσιακές στράτες των Θεσσαλών μετακινούμενων κτηνοτρόφων, οι οποίες αποτελούσαν/αποτελούν χωρικά το συνδετικό κρίκο μεταξύ των χειμερινών και καλοκαιρινών βοσκοτόπων και έγινε διαχρονική αποτύπωση των χρήσεων/καλύψεων γης των περιοχών αυτών και υπολογίστηκαν δείκτες τοπίου για την αξιολόγησή του. Επιπλέον, μέσω συνεντεύξεων καταγράφηκε η αντίληψη των ίδιων των κτηνοτρόφων για τις οικοσυστημικές υπηρεσίες που προσφέρει η μετακινούμενη κτηνοτροφία και τα οφέλη αυτής. Τέλος, πραγματοποιήθηκε εθνοβοτανική έρευνα για την καταγραφή των αυτοφυών φυτών που χρησιμοποιούσαν κατά τη δραστηριότητα αυτή. Σύμφωνα με τα αποτελέσματα της έρευνας, τρεις διαφορετικές εθνοτικές ομάδες, Σαρακατσαναίοι, Βλάχοι και Κουπατσαραίοι, είναι αυτές που μετακινούσαν/μετακινούν τα ζώα το καλοκαίρι σε ορεινά λιβάδια με τις δύο τελευταίες ομάδες να παρουσιάζουν κοινή διαδρομή. Αν και μέρος των Βλάχων κτηνοτρόφων πραγματοποιεί ακόμη και σήμερα τη μετακίνηση με τα πόδια, τα αποτελέσματα δεν έδειξαν διαφορές μεταξύ της διαδρομής που πραγματοποιούσαν αυτοί, με τη διαδρομή που πραγματοποιούσαν οι Σαρακατσαναίοι κτηνοτρόφοι. Στις δύο αυτές διαδρομές, προέκυψε μείωση των ποολίβαδων και αύξηση των εκτάσεων που αποτελούν τα θαμνολίβαδα και τα δάση προκαλώντας μείωση της ετερογένειας του τοπίου. Είκοσι εννέα οικοσυστημικές υπηρεσίες, οι οποίες αντιπροσωπεύουν και τις τέσσερις κύριες ομάδες οικοσυστημικών υπηρεσιών καταγράφηκαν στις τρεις εθνοτικές ομάδες. Επιπλέον, υπολογίστηκε η ομοιότητα μεταξύ των ομάδων ως προς την αντίληψη για τις οικοσυστημικές υπηρεσίες που προσφέρει η μετακινούμενη κτηνοτροφία. Σύμφωνα με τα αποτελέσματα η ομοιότητα είναι μεγάλη και ιδιαίτερα μεταξύ Σαρακατσαναίων-Βλάχων. Η εθνοβοτανική έρευνα έδειξε πως χρησιμοποιούσαν 79 διαφορετικά φυτά που ανήκουν σε 29 οικογένειες, με την οικογένεια των Rosaceae να είναι η πολυπληθέστερη (12 είδη).
A systematic review of automated journalism scholarship: guidelines and suggestions for future research
Authors: Danzon-Chambaud Samuel
Published: March 2021

Background: The use of advanced algorithmic techniques is increasingly changing the nature of work for highly trained professionals. In the media industry, one of the technical advancements that often comes under the spotlight is automated journalism, a solution generally understood as the auto generation of journalistic stories through software and algorithms, without any human input except for the initial programming.

Methods: In order to conduct a systematic review of existing empirical research on automated journalism, I analysed a range of variables that can account for the semantical, chronological and geographical features of a selection of academic articles as well as their research methods, theoretical backgrounds and fields of inquiry. I then engaged with and critically assessed the meta-data that I obtained to provide researchers with a good understanding of the main debates dominating the field.

Results: My findings suggest that the expression “automated journalism” should be called into question, that more attention should be devoted to non-English speaking scholarship, that the collective and individual impacts of the technology on media practitioners should be better documented and that well-established sociological theories such as institutionalism and Bourdieu’s field theory could constitute two adequate frameworks to study automated journalism practices.

Conclusions: This systematic literature therefore provides researchers with an overview of the main challenges and debates that are occurring within the field of automated journalism studies. Future studies should, in particular, make use of institutionalism and field theory to explore how automated journalism is impacting the work of media practitioners, which could help unearth common patterns across media organisations.
A Rationale for Imperfect Reporting Standards
Authors: Friedman Henry L. , Hughes John S. , Michaeli Beatrice
Published: March 2021

The aim of general purpose financial reporting is to provide information that is useful to investors, lenders, and other creditors. With this goal, regulators have tended to mandate increased disclosure. We show that increased mandatory disclosure can weaken a firm’s incentive to acquire and voluntarily disclose private information that is not amenable to inclusion in mandated reports. Specifically, we provide conditions under which a regulator, seeking to maximize the total amount of information provided to investors via both mandatory and voluntary disclosures, would mandate less informative and more conservative financial reports even in the absence of any direct costs of increasing informativeness. This result is robust to allowing the firm to make reports more informative and to imposing a nondisclosure cost or penalty on the firm. The results and comparative statics analysis contribute to our understanding of interactions between mandatory reporting and voluntary disclosure and demonstrate a novel benefit to setting accounting standards that mandate imperfectly informative reports.

This paper was accepted by Suraj Srinivasan, accounting.
Analyses of pattern quality in roll-to-roll digital maskless
lithography with positional errors
Authors: Lee Changmin , Ko Yunhyeok , Hahn Jae W.
Published: March 2021

In roll-to-roll digital maskless lithography (R2R DML) equipment, it is difficult to
achieve high quality, owing to surface deformation that affects the
pattern position. To address this issue, we simulated the patterning
results of R2R DML to analyze the relationship between positional
errors and pattern quality. Errors perpendicular to the pattern
direction exhibited a 1.3–2 times greater effect on the linewidth and
line edge roughness compared to those parallel to this direction. We
confirmed that positioning errors could lead to defects in which the
photoresists were not fully exposed. Finally, through simulations, we
found that the effect of positional errors could be reduced by
controlling the array spot separation length.
Application of digital holographic tomography in antitumor effect of cantharides complex on 4T1 breast cancer cells
Authors: Lu Chen-Wen , Belashov Andrey V. , Zhikhoreva Anna A. , Semenova Irina V. , Cheng Chau-Jern , Su Li-Yu , Wu Chung-Hsin
Published: March 2021

The study focuses on a methodology providing noninvasive monitoring and evaluation of the antitumor effect of traditional Chinese medicine, cantharides complex (canth), on 4T1 breast tumor cells. Digital holographic tomography (DHT) and developed data post-processing algorithms were used for quantitative estimation of changes in optical and morphological parameters of cells. We calculated and compared data on the refractive index, thickness, and projected area of 4T1 breast tumor cells in control untreated specimens and those treated with doxorubicin hydrochloride (DOX), canth, and their combinations. Post-treatment changes in cellular morphology recorded by DHT demonstrated that the two drugs led to noticeably different morphological changes in cells that can be presumably associated with different pathways of their death, apoptosis, or necrosis. The effect of combined treatment with these two drugs strongly depended on their relative concentrations and could lead to changes characteristic either for DOX or for canth; however, being more profound than those obtained when using each drug solely. The results obtained by DHT are in a good correspondence with commonly used cell viability analysis and immunofluorescent analysis of changes in cellular cytoskeleton.
Polarization singularity index determination by using a tilted lens
Authors: Komal Baby , Deepa S. , Kumar Sunil , Senthilkumaran P.
Published: March 2021

The superposition of spin and orbital angular momentum states of light
generates polarization singularities. By perturbing and disintegrating
their component orbital angular momentum (OAM) states, the
polarization singularity indices can be determined. The spatially
varying polarization distribution of these beams possesses information
about the helical wavefront structures of the component OAM states,
although they have plane wavefronts. The polarization singular beam
(PSB) is focused using a tilted lens, and the intensity distribution
at a predicted position in the direction of propagation is used to
determine the component OAM content in the beam. Astigmatism
introduced by the tilt of the lens modulates the vortex beam to
introduce intensity nulls in the propagated beam. We demonstrate by
simulations and experiments the index determination of the V points
and C points using a tilted lens. This method is effective in the
index determination of V points and C points formed by the
superposition of component scalar vortices having opposite-sign
topological charges. The degeneracy of C points with the same Stokes
indices can be lifted through this technique.
Synchronously pumped Raman laser for simultaneous degenerate and nondegenerate two-photon microscopy
Authors: Buttolph Michael L. , Mejooli Menansili A. , Sidorenko Pavel , Eom Chi-Yong , Schaffer Chris B. , Wise Frank W.
Published: March 2021

Two-photon fluorescence microscopy is a nonlinear imaging modality frequently used in deep-tissue imaging applications. A tunable-wavelength multicolor short-pulse source is usually required to excite fluorophores with a wide range of excitation wavelengths. This need is most typically met by solid-state lasers, which are bulky, expensive, and complicated systems. Here, we demonstrate a compact, robust fiber system that generates naturally synchronized femtosecond pulses at 1050 nm and 1200 nm by using a combination of gain-managed and Raman amplification. We image the brain of a mouse and view the blood vessels, neurons, and other cell-like structures using simultaneous degenerate and nondegenerate excitation.
Spiral spectrum of high-order elliptic Gaussian vortex beams in a non-Kolmogorov turbulent atmosphere
Authors: Wang Yankun , Bai Lu , Xie Jinyu , Zhang Danmeng , Lv Qiang , Guo Lixin
Published: March 2021

In a free space optical communication system based on vortex beams, the effects of spread and crosstalk caused by atmospheric turbulence should not be ignored. The orbital angular momentum (OAM) spectrum of the signal based on elliptic Gaussian beam (EGB) after propagation through non-Kolmogorov turbulent atmosphere are deduced, and a theoretical model of the spiral spectrum of EGB propagating through turbulent atmosphere is obtained. Numerically calculated OAM modes detection and crosstalk probability under different ellipticity parameters. The results show that the ellipticity parameter has a significant impact on the OAM spectral distribution of EGB and the transmission characteristics after turbulent atmosphere. The selection of appropriate ellipticity parameter can correspondingly reduce the degradation and crosstalk caused by turbulent atmosphere. We also compared a Laguerre-Gaussian beam (LGB) with EGB and pointed out the advantages and limitations of these two kinds of beams. The research results may be useful in the field of short distance optical communication and OAM-based multiplex communication.
Experimental phase control of a 100 laser beam array with quasi-reinforcement learning of a neural network in an error reduction loop
Authors: Shpakovych Maksym , Maulion Geoffrey , Kermene Vincent , Boju Alexandre , Armand Paul , Desfarges-Berthelemot Agnès , Barthélemy Alain
Published: March 2021

An innovative scheme is proposed for the dynamic phase control of a laser beam array. It is based on a simple neural network included in a phase correction loop that predicts the complex field array from the intensity of the induced scattered pattern through a phase intensity transformer made of a diffuser. A crucial feature is the use of a kind of reinforcement learning approach for the neural network training which takes account of the iterated corrections. Experiments on a proof-of-concept system demonstrated the high performance and scalability of the scheme with an array of up to 100 laser beams and a phase setting at λ/30.
Doubling the FOV of AR displays with a liquid crystal polarization-dependent combiner
Authors: Yin Kun , He Ziqian , Li Kun , Wu Shin-Tson
Published: March 2021

We propose a glasses-like augmented reality (AR) display with an extended field-of-view (FOV) using a liquid crystal polarization-dependent combiner (PDC). Such a PDC consists of two polarization volume lenses (PVLs) that are based on patterned liquid crystals to selectively control the beam path according to the right-handed or left-handed circularly polarized light. By encoding the left and right half of the FOV into two orthogonal polarization states, the overall horizontal FOV can be doubled while maintaining an ultrathin and flat form factor. Based on this multiplexing concept, the FOV can be further extended by integrating more PVLs with different diffraction angles. The proposed configuration with polarization-time multiplexing provides a promising solution for overcoming the limited FOV issue in AR displays.
Reduction of excess intensity noise of picosecond Yb soliton fiber lasers in a >10-mW power regime
Authors: Dai Gaoyu , Katoh Kazuhiro , Ozeki Yasuyuki
Published: March 2021

We demonstrate that excess intensity noise of soliton fiber lasers in the average power regime exceeding 10 mW can be reduced by increasing the intracavity dispersion and reducing the pump power. Based on this strategy, we present a polarization-maintaining picosecond Yb fiber laser mode-locked by a nonlinear amplifying loop mirror whose excess noise is equal to the shot noise at an optical power of >10 mW.
Melting phase change heat transfer in a quasi-petal tube thermal energy storage unit
Authors: Mehryan S. A. M. , Raahemifar Kaamran , Ramezani Sayed Reza , Hajjar Ahmad , Younis Obai , Talebizadeh Sardari Pouyan , Ghalambaz Mohammad
Published: March 2021

In the present study, the thermal energy storage of a hot petal tube inside a shell-tube type Thermal Energy Storage (TES) unit was addressed. The shell is filled with the capric acid Phase Change Material (PCM) and absorbs the heat from a hot U-tube petal. The governing equations for the natural convection flow of molten PCM and phase change heat transfer were introduced by using the enthalpy-porosity approach. An automatic adaptive mesh scheme was used to track the melting interface. The accuracy and convergence of numerical computations were also controlled by a free step Backward Differentiation Formula. The modeling results were compared with previous experimental data. It was found that the present adaptive mesh approach can adequately the melting heat transfer, and an excellent agreement was found with available literature. The effect of geometrical designs of the petal tube was investigated on the melting response of the thermal energy storage unit. The phase change behavior was analyzed by using temperature distribution contours. The results showed that petal tubes could notably increase the melting rate in the TES unit compared to a typical circular tube. Besides, the more the petal numbers, the better the heat transfer. Using a petal tube could increase the charging power by 44% compared to a circular tube. The placement angle of the tubes is another important design factor which should be selected carefully. For instance, vertical placement of tubes could improve the charging power by 300% compared to a case with the tubes’ horizontal placement.
Elucidating the immune infiltration in acne and its comparison with rosacea by integrated bioinformatics analysis
Authors: Yang Lu , Shou Yan-Hong , Yang Yong-Sheng , Xu Jin-Hua
Published: March 2021

Background

Acne vulgaris and rosacea are common inflammatory complications of the skin, both characterized by abnormal infiltration of immune cells. The two diseases can be differentiated based on characteristic profile of the immune cell infiltrates at the periphery of disease lesions. In addition, dysregulated infiltration of immune cells not only occur in the acne lesions but also in non-lesional areas of patients with the disease, thus characterizing the immune infiltration in these sites can further enhance our understanding on the pathogenesis of acne.

Methods

Five microarray data-sets (GSE108110, GSE53795, GSE65914, GSE14905 and GSE78097) were downloaded from Gene Expression Omnibus. After removing the batch effects and normalizing the data, we applied the CIBERSORT algorithm combined with signature matrix LM22, to describe 22 types of immune cells’ infiltration in acne less than 48 hour (H) old, in comparation with non-lesional skin of acne patients, healthy skin and rosacea (including erythematotelangiectatic rosacea, papulopustular rosacea and phymatous rosacea) and we compared gene expression of Th1 and Th17-related molecules in acne, rosacea and healthy control.

Results

Compared with the non-lesional skin of acne patients, healthy individuals and rosacea patients, there is a significant increase in infiltration of neutrophils, monocytes and activated mast cells around the acne lesions, less than 48 H after their development. Contrarily, few naive CD4+ T cells, plasma cells, memory B cells and resting mast cells infiltrate acne sites compared to the aforementioned groups of individuals. Moreover, the infiltration of Regulatory T cells (Tregs) in acne lesions is substantially lower, relative to non-lesional sites of acne patients and skin of healthy individuals. In addition, non-lesional sites of acne patients exhibit lower infiltration of activated memory CD4+ T cells, plasma cells, memory B cells, M0 macrophages, neutrophils, resting mast cells but higher infiltration of Tregs and resting dendritic cells relative to skin of healthy individuals. Intriguingly, we found that among the 3 rosacea subtypes, the immune infiltration profile of papulopustular rosacea is the closest to that of acne lesions. In addition, through gene expression analysis of acne, rosacea and skin tissues of healthy individuals, we found a higher infiltration of Th1 and Th17 cells in acne lesions, relative to non-lesional skin areas of acne patients.

Conclusions

Our study provides new insights into the inflammatory pathogenesis of acne, and the difference between acne and rosacea, which helps in differentiating the two diseases. Our findings also guide on appropriate target therapy of the immune cell infiltrates in the two disease conditions.
Three Dimensional Quantitative Structure Activity Relationship and Molecular
Docking Studies of Flavonoids as Reverse Transcriptase Inhibitors
Authors: Sarkar Bikash Kumar , Giri Nabanita
Published: March 2021

A set of 29 flavonoid molecules are used to generate comparative
molecular field analysis (CoMFA) and comparative molecular
similarity indices analysis (CoMSIA) models. The best CoMFA model
showed a cross-validated correlation coefficient (q2) = 0.762, noncross-
validated correlation coefficient (r2) = 0.939, standard error of
estimate (S) = 0.038 and F = 396. And that for CoMSIA model were
q2 = 0.758, r2 = 0.957, S = 0.063 and F = 236. The models show a high
predictive ability, validated by 11 favonoid molecules. The docking
studies shows the hydrogen bonding interaction is mostly responsible
for binding of the flavonoids molecules in the binding pocket of HIV
1-RT protein (3HVT.pdb).
Theoretical Bioevaluation of 1,2,4-Thiadiazole-1,2,4-triazole Derivatives via Molecular Modelling Approach
Authors: Kolawole Oyebamiji Abel , Adewale Akintelu Sunday , Odoemene Simon N. , Emmanuel Oyeneyin Oluwatoba , Banjo Semire
Published: March 2021

Breast cancer still remains one of the precarious ailments among humans globally. The vulnerability
of this ailment in homeopathic world remains colossal and this has drawn the attention of seasoned
researchers to find lasting solution to this hazard. Therefore, 10 novel 1,2,4-thiadiazole-1,2,4-triazole
derivatives were studied so as to explore their anti-breast cancer activities. The studied compounds
were optimized using Spartan 14 and the QSAR study was executed by using Gretl and MATLAB.
Also, docking study was observed using Pymol (for treating downloaded protein), Autodock Tool (for
locating binding site in the downloaded protein and for converting ligand and receptor to .pdbqt format
from .pdb format), Auto dock vina (for docking calculation) and discovery studio (for viewing the nonbonding
interaction between the docked complexes). The selected descriptors were used to developed
effective QSAR model and it was observed that the developed QSAR model using artificial neural
network (ANN) predicted better than the prediction made by multiple linear regression (MLR). More
so, the calculated binding affinity revealed that compound g (-11.4 kcal/mol) possess ability to inhibit
3α-hydroxysteroid dehydrogenase type 3 (PDB ID: 4xo6) than other studied compounds as well as
etoposide (Standard).
To Evaluate the Effectiveness of Lactational Counseling on Prevention of Breast Engorgement among Postnatal Mothers
Authors: Gavhale Pradnya Ravindra , Moon Shalini Haridas
Published: March 2021

BACKGROUND Breast engorgement is swollen, painful breasts with overfilling of breast milk. It is normally due to an imbalance between supplying & sucking of milk from the breast. In lactating mothers, this condition is common during the puerperal period. If breast engorgement is not cured, it will cause mastitis. The incidence rate of mastitis in India is 2 - 5 % in lactating & 1 % in non-lactating women. Signs of breast engorgement are the inflamed and oedematous mammary gland & the shiny & diffusely red skin of breast. The female may have pyrexia & that usually reduces over a period of 24 hours. The nipples could stretch, be tight & flat which makes it difficult for the baby to suck milk from the breast. METHODS Research approach was interventional evaluatory approach. Research design was pre-experimental post-test design. The study was conducted in AVBR hospital Sawangi Meghe, Wardha district. Sample consisted of post-natal mothers. Sampling technique was a non-probability purposive sampling technique. Sample size was of 40. Tool used was a structured questionnaire including socio-demographic & breast engorgement assessment scale. RESULTS All postnatal mothers had normal breast engorgement score at day 1, at day 2; 92.5 % of the postnatal mothers had normal and 7.5 % had mild engorgement at day 3; 77.5 % of postnatal mothers had normal, 15 % had mild and 7.5 % had moderate engorgement; and at day 4, 7.5 % had mild and 7.5 % had moderate engorgement. By using the chi-square test statistically, no significant difference was found in breast engorgement score at day 1 and at day 2 (א2 = 3.11, p = 0.07), and a significant difference was found between day 1 and day 3 (א2-value = 10.14, p = 0.006) and between day 1 and day 4 (א2-value = 11.43, p = 0.003). CONCLUSIONS This study reveals that there was no significant difference on the first and second day but on the 3rd and 4th day, significant difference was there. After lactational counseling, breast engorgement score was reduced. Lactational counseling is important for the prevention of breast engorgement. KEY WORDS Evaluate, Effectiveness, Breast Engorgement, Lactational Counselling, Postnatal Mother
A Comparative Clinical Study on Surgical Blade and Diode Laser in the Treatment of Gingival Melanin Pigmentation
Authors: Jain Somit Kumar , Shenoy Nina , Chourasia Mehul Kumar , Ramesh Amitha
Published: March 2021

BACKGROUND Gingival melanin pigmentation (GMP) is a common aesthetic concern. The gold standard for depigmentation, is surgery. Recently soft tissue lasers have gained popularity. The purpose of this study was to compare and evaluate the clinical efficacy of surgical blade and laser treatment in terms of pain perception and wound healing outcomes, 7 and 14 days following the procedures for the treatment of gingival depigmentation. METHODS This 14 day follow up comparative clinical study, utilized a split mouth design, in the anterior region. Fifteen patients with moderate to heavy bilateral gingival pigmentation were included as per the criteria by Dummett et al. The patients’ right side (group 1) was treated with surgical blade and the left side (group 2) with diode laser (Picasso, AMD LASERS™) by a trained clinician. Pain perception was assessed using Visual Analog Scale (VAS) and wound healing was assessed using clinical parameters. RESULTS Data was analysed using paired t test and Wilcoxon’s signed rank test. P value of < 0.05 was considered statistically significant. On day 7, more than 70 % patients had slight pain in group 1. Whereas, 47 % experienced no pain in group 2. The mean difference in VAS scores between the groups at day 7, was statistically significant. No statistically significant distinction in wound healing was observed 7 days following both procedures. No pain, and complete epithelialisation was noted in both groups on day 14. CONCLUSIONS Pain experienced by the patients was slightly more in the scalpel group compared to laser. There was no difference in wound healing between both groups. KEY WORDS GMP, Gingival Melanin Pigmentation, VAS Scale, Depigmentation, Wound Healing, Laser, Surgical Blade, Split Mouth Design
Estimation of Age Using Dimensions of Apical Foramina of Teeth
Authors: Behera Aklesha , Santhanam Archana , Sherlin Herald J. , Jayaraj Gifrina , K.R. Don
Published: March 2021

BACKGROUND Forensic odontology is an ever growing and a flourishing science. The science deals in criminal laws by using dental knowledge. People who practice forensic odontology are called as forensic dentists. They are asked to determine the age, sex, race, occupation, previous dental history and various other determinants like DNA verification in unidentified human beings. Teeth are a very special tissue in the human body. Teeth are the only tissue which can survive through extreme climatic and environmental conditions like heat, cold etc. hence many a times retains its morphology. Age estimation has been studied by many researchers but age estimation methods have been incapable of providing the age estimation in older age groups. The study aims to determine the age using the dimensions of the apical foramen from middle age to old age groups. METHODS A descriptive ex vivo study, was done from December 2019 to March 2020. Freshly extracted teeth were collected and cleaned using hydrogen peroxide. The teeth selected were single rooted teeth like incisors, canine and premolars in the age group of 30 to 40 years, 41 - 50 years, 51 - 60 years and 61 - 70 years. Apical one third of the teeth was sectioned, mounted over a slide and placed perpendicular to the lens of the stereomicroscope. Using Mag Vision and Image J software, photomicrographs and measurements were taken. Data procured was tabulated and statistical analysis was done using Statistical Package for the Social Sciences (SPSS) version 20. RESULTS In 30 - 40 years age group, the mean diameter of all single rooted teeth was 0.35 mm. Among the 41 - 50 years age group, the mean diameter was 0.43mm. In 51 - 60 years age group it was 0.41mm and in the 61 - 70 years age group, the mean diameter was 0.36 mm. Pearson chi square P value for incisor is 0.280, canine is 0.223 and premolar is 0.326. CONCLUSIONS Age estimation can be done using physiological dimensions of apical foramen. From the present study, dimensions of apical foramen decreases with increasing age due to cementum deposition. KEY WORDS Age Determination, Apical Foramen Diameter, Single Rooted Teeth
Sozial-ökologische Krise und kollektives Landeigentum
Authors: Dannenberg Janina
Published: March 2021

Gerodete Wälder, Landspekulationen, Care-Krise: Kann gemeinschaftliches Eigentum helfen, die sozial-ökologische Krise zu überwinden? In den Philippinen sind vorkoloniale kollektive Landrechte Indigener rechtlich anerkannt. Wie manifestiert sich unter diesen Bedingungen die sozial-ökologische Krise? Mit feministischer Forschungsperspektive nähert sich Janina Dannenberg dieser Frage in einer Fallstudie zu Materialität und Alltagspraxis der Matigsalug Manobo in Bukidnon an. Der (Re)Produktivitätsansatz, der analytisch feministische Ökonomiekritik und Ökologische Ökonomik miteinander verbindet, wird dezidiert empirisch getestet, kritisch diskutiert und im Sinne von Bruno Latours »Nichtmoderne« erweitert.
A Nexus Approach to Water, Energy, and Food Security in Northern Canada
Authors: Natcher David , Ingram Shawn
Published: March 2021

Residents of northern Canada experience high rates of water, energy, and food (WEF) insecurity relative to the national average. Historically, WEF systems have been treated independently with little policy or institutional coordination occurring between sectors. This paper presents the results of a WEF nexus analysis for northern Canada. We assess the positive and negative interactions between the WEF sectors that could facilitate or impede the attainment of WEF-related sustainable development goals. Out of 210 pair-wise interactions, 87% were found to be synergistic of some magnitude, meaning that efforts to address insecurity in one WEF sector will have positive spillover effects toward the others. With synergies significantly outweighing trade-offs, opportunities exist to simultaneously address WEF insecurities through mutually beneficial actions that capitalize on and promote synergetic policies.
Range Extension of Northern Form Dolly Varden (Salvelinus malma malma) to the Upper Arctic Red River Watershed, Northwest Territories, Canada
Authors: Maier Kris W.C. , Mochnacz Neil J. , Bajno Robert , Chapelsky Andrew J. , Rodger Peter , Reist James D.
Published: March 2021

Northern form Dolly Varden is an anadromous char with significant ecological value found in high-gradient rivers of the Western Arctic. Because of declines in population abundance, Dolly Varden was recently designated as “Special Concern” under the federal Species at Risk Act. This species is also of great cultural and dietary significance to Indigenous Peoples of many communities in the Western Arctic; thus, expanding knowledge of the distribution, biology, and essential habitat is an important priority. We present results of a fisheries survey in the headwaters of the Arctic Red River, Northwest Territories, that focused on confirming the presence of Dolly Varden. Of 143 fish captured among 12 sampling locations, two were Arctic grayling (Thymallus arcticus), 33 were slimy sculpin (Cottus cognatus), and 108 were char identified using qualitative and quantitative morphological features. A subsample of 44 char voucher specimens were frozen whole and later identified using a linear discriminant function (LDF) based on meristic counts and morphological measurements, and a mitochondrial DNA genetic marker. LDF scores indicated that char collected in the Arctic Red River were northern form Dolly Varden. Genetic analysis showed that all but one char possessed mitochondrial DNA sequences common in northern form Dolly Varden from Canada. Our results confirm the presence of Dolly Varden in the Arctic Red River headwaters, extending the confirmed known distribution of this taxon in the Northwest Territories approximately 450 km south and 100 km east of previously delimited areas.
The River Alazeya: Shifting Socio-Ecological Systems Connected to a Northeastern Siberian River
Authors: Mustonen Tero , Shadrin Vyacheslav
Published: March 2021

One of the most remote Arctic locations, Andryushkino village of Yukaghir and Even peoples is located on the shore of the river Alazeya in northeastern Siberia, in the Lower Kolyma Republic of Sakha-Yakutia, Russia. The community is at the nexus of large-scale Arctic social and climate change resulting from economic shifts, permafrost melt events, and high temperatures. In this study, we approach Indigenous knowledge of climate impacts to water by investigating the role of the river Alazeya, which has enabled human life to thrive, given rise to the Indigenous governance of landscapes in the past, and today serves most of the Indigenous peoples in the region for their culture, food security, and well-being. To do this, we offer an ambitious system-change analysis of the socio-ecological context of the river basin and community by exploring oral histories recorded in the community between 2005 and 2020, combining them with relevant scientific literature and weather data from Russian measurement stations to detect and point to key messages of impacts. Our results confirm that the speed and extent of climate warming have increased since 1985. The flood event of 2007 in the village has especially been seen as a major climate change-induced catastrophe. We focus on the drivers of change from local history to present. We also investigate alternatives for future development of resilience and support for the Yukaghir culture, traditional ways of life, and language.
Reconfigurando o currículo e discutindo questões étnico-raciais em um curso técnico
Authors: Souza Pimenta Sara , Steveen Moreno Rodriguez Andrei , Prestes Massena Elisa
Published: March 2021

O currículo escolar, muitas vezes, tem sido decidido por classes dominantes e expressa conteudismo e descontextualização. No entanto, movimentos sociais têm impulsionado modificações no currículo para o tratamento de questões étnico-raciais. Na busca pela contextualização com a realidade e integração entre as ciências, objetivamos investigar os processos de ensino e aprendizagem por meio do desenvolvimento de uma proposta de reconfiguração curricular com o tema cuidado de cabelos crespos e cacheados. Para isso, a proposta foi desenvolvida e implementada em uma escola técnica com trinta e dois estudantes participantes, os quais responderam a um questionário e elaboraram duas produções textuais. Os dados foram analisados à luz da Análise Textual Discursiva da qual obtivemos três categorias emergentes, a saber: O processo de rejeição/aceitação da identidade por meio do cabelo; Níveis de compreensão do conteúdo; e, O problema do consumo em detrimento da reafirmação da identidade. Os resultados apontam que a aceitação da identidade racial negra aparece entre os estudantes por meio dos cabelos cacheados, mas, nesse processo, está inserito o problema do consumismo. Além disso, conforme expresso nas atividades, os estudantes apresentaram evidências da aprendizagem de conteúdos químicos por meio do tema discutido.
Publicly subsidized private schools in developing countries: Lessons from Colombia
Authors: Diaz Rios Claudia , Urbano Canal Nathalia
Published: March 2021

Educational public-private partnerships (EPPPs) promise to increase education access and quality in developing countries, provided they have an adequate design that restricts the distribution of subsidies including targeted programs, centralized controlled enrolment, and accountability. This study investigates the effects of publicly subsidized private schools (PSPS) in Colombia—a type of EPPP program that follows all of these recommendations. We use propensity score and regression techniques to identify PSPS effects on student achievement, measured by national standardized tests. Our results show that Colombian PSPS serve vulnerable students, who are fairly similar to those attending traditional public schools (TPS). Nevertheless, students at PSPS underperform compared to TPS students. Our conclusion suggests that design restrictions may prevent student selection and self-selection, but do not guarantee quality improvement for disadvantaged students at subsidized schools. We also argue that design restrictions for PSPS may not be enough when private providers are scarce or difficult to attract for serving the most disadvantaged population.
Does Texas’ compensatory education funding get to the intended students?
Authors: Toenjes Laurence A.
Published: March 2021

Two questions about Texas school expenditure patterns are examined. First, “How progressive are spending patterns among high and low poverty schools?” Second, “How unequal are expenditures per pupil between schools with at least 70% of their students classified as economically disadvantaged, in different districts?” The data, for school year 2017-2018, are restricted to 3,453 elementary and middle schools in 90 large Texas districts. The schools in each district were divided into high and low poverty groups. The differences in the average per pupil spending for operations between the two groups ranged from plus $1,382 in one district to a negative $802 in another. The average expenditures in schools with at least 70% economically disadvantaged students were 75% greater in one district than in another. It is demonstrated that districts with less extreme average levels of low-income students have more opportunity to act as good Samaritans, generally exhibiting substantially greater spending in their high poverty schools. This finding supports arguments for student funding weights that increase with increasing proportions of economically disadvantaged students. An incidental finding is that a commonly used measure of funding progressivity is a direct function of district and school level variances in poverty averages, and is therefore biased by them.
Czynniki oraz efekty lokalizacji zakładu Volkswagena w powiecie wrzesińskim
Authors: Dyba Wojciech
Published: March 2021

W artykule przedstawiona została analiza czynników i efektów lokalizacji zakładu produkcyjnego Volkswagen Crafter w Białężycach koło Wrześni. Uzyskane wyniki oparte są na wywiadach przeprowadzonych z przedstawicielami przedsiębiorstwa i władz samorządowych oraz z mieszkańcami. Badanie pozwoliło wykazać, że w zakresie czynników lokalizacji – obok kosztowych (związanych z terenem inwestycji i ulgami podatkowymi) – znaczenie miały też czynniki zaopatrzeniowe (m.in. oczekiwana wydajność pracy) oraz „miękkie” (m.in. dobry wizerunek regionu, współpraca z władzami lokalnymi). Wśród korzyści dla powiatu wrzesińskiego, jakie wynikają z inwestycji i działań podejmowanych przez władze zakładu, są przede wszystkim: utworzenie nowych miejsc pracy, sponsoring lokalnych imprez i wydarzeń, finansowanie akcji prośrodowiskowych, a także wzrost obrotów w lokalnym sektorze usługowym, napływ mieszkańców i lokalizowanie firm współpracujących z Volkswagenem.
Virtual Laboratory to Support a Practical Learning of Micro Power Generation in Indonesian Vocational High Schools
Authors: Bima Marshal , Saputro Herman , Efendy Agus
Published: March 2021

The rapid changes in industrial revolution 4.0 demand change in education, especially at vocational education. Teachers in Vocational High School (VHS) in Indonesia are expected to bring technology-based innovations to achieve success in learning. Learning facilities are one of the factors supporting the success of learning class. Ideally, Indonesian Vocational High Schools have facilities and infrastructure following industrial. Currently, schools have difficulty providing learning support facilities and infrastructure following those in the industry. Thus, the equipment in the school laboratory is irrelevant to the existing equipment in the industry. The practicum apparatus gap between VHS and industry requires appropriate and effective solutions. The gap occurred in practical learning of micro power generation Indonesian VHS. On the other hand, virtual laboratories in the learning process can help students learn an object that cannot be presented in the classroom. By using virtual laboratories, students learn to use industry apparatus through virtual forms. This research aims to overcome the problem of practical learning in VHS, especially on practical learning of micro power generation through the virtual laboratory. This study used the 4D model approach (Define, Design, Develop, and Disseminate). The result showed that the virtual laboratory of micropower generation effectively supported learning and transfer of knowledge in practical learning, especially during the covid 19 pandemics.
Efficiency of electric vehicle interior heating systems at low ambient temperatures
Authors: Gis Maciej , Wiśniowski Piotr , Bednarski Mateusz
Published: March 2021

The electric car market is becoming more and more extensive. According to ACEA, in 2019, 549,387 full electric passenger vehicles, hybrid plug-ins and hydrogen vehicles were registered in the European Union. Thus, it is an increase of 52.9 percent compared to 2018. Germany is the leader with 108 839 registrations of vehicles (+60.9% y/y). Great Britain achieved an increase of 21.5 percent y/y and the number of registrations at 72 834 pieces. The Netherlands came next (66 957 pcs, + 146.3% y/y), France (61 356 pcs, +34.6% y/y) and Sweden (40 406 pcs, + 39.4% y/y).

Registration results in Europe shows that the popularity of electric vehicles is increasing. Along with the development of this type of vehicles, the technology used in their construction also changes. The biggest calls at the moment are batteries for these vehicles, as well as their ranges on a single charge. There are already vehicles with ranges of 500 km or even 600 km.

However, it turns out that these are not the only problems with electric vehicles One of the drawbacks is the way they heat their passenger cabins. There is no typical heater in an electric vehicle as in the case of a vehicle with a conventional drive. For this purpose, e.g. an electric heater with a blower is used for this purpose. For this reason, the authors of the paper decided to determine the efficiency of the heating system in an electric vehicle at low ambient temperatures.

Own tests were carried out on the vehicle at temperatures of +5°C, −5°C and −10°C. Based on the research, the authors of the paper could draw conclusions on how to heat the interior in the electric vehicle under test, as well as check whether the efficiency of such a system for individual places in the car is sufficient to obtain the set temperature.
Prediction of the parameters and the hot open die elongation forging process on an 80 MN hydraulic press
Authors: Dindorf Ryszard , Takosoglu Jakub , Wos Piotr
Published: March 2021

The main task of the study was to develop and implement predictive control in the hot open die forging process of heavy, large, and hard deformable steel forgings on an 80 MN hydraulic press at the Forged Products Department (FPD) of Celsa Huta Ostrowiec (CHO). The predicted hot flow stresses and the predicted deformation/forging forces as a function of the parameters of the elongation forging process were determined. The predicted parameters of the forging process were included in the dynamic model of the hydraulic forging press. Generalized predictive control (GPC) algorithm of the hot open-die forging process on the hydraulic press was developed. The use of predictive control solved the uncertainty of the hot open forging process, which depends on the dimensions, shapes, and material properties of the forgings, as well as the parameters of the hydraulic press and forging tools.