bluuebunny/crossref_metadata_2025 huggingface dataset:
Åbne Sider - Kultursyn i læreplaner: Udvikling inden for undervisning i dansk som andetsprog for voksne
Authors: Petersen Karen Bjerg
Published: October 2022

I denne artikel har jeg fokus på læreplansdokumenter, specielt lovgivning og bekendtgørelser...
Risikofyldte test – erfaringer fra dansk testhistorie
Authors: Ydesen Christian
Published: October 2022

I 1930 påbegyndte psykolog og kommunelærer Henning Meyer sitskolepsykologiske....
Brug af internetbaseret sprogkorpus på sprogstudiet
Authors: Pedersen Johan
Published: October 2022

Det er de færreste studerende der har hørt om korpusundersøgelserog ved hvad et sprogkorpus [...]
Udvalgte Links til temanummeret
Authors: Lund Karen
Published: October 2022

...
Kronikken - Statsborgerskab til verdensborgeren
Authors: Ersbøll Eva
Published: October 2022

Kronikken i dette temanummer om verdensborgeren skal handleom statsborgerskab og særligt om [...]
Kinesisk i nordjyske skoler – hvorfor nu det?
Authors: Egekvist Jlla Egidiussen , Kirkebæk Mads
Published: October 2022

Killick (2009) argumenterer for, at internationalisering er uddannelsessystemetsrespons på globaliseringen, og udviklingen i Danmarksynes at underbygge [...]
Ny læreruddannelse og sprogfag
Authors: SØNDERGAARD GREGERSEN ANNETTE
Published: October 2022

Læreruddannelsen står igen til ændringer i såvel struktur som indhold, og der er tale om et radikalt brud med...
Den nordiske diskurs og den gode praksis
Authors: Vedel Peter Villads
Published: October 2022

Det kan anbefales at læse rapporten »Integration gennem voksen- og efteruddannelse« (Wahlgren m.fl. 2010), der...
Akademiske ord og fraser – et nordisk projekt
Authors: HENRIKSEN BIRGIT , JAKOBSEN ANNE SOFIE
Published: October 2022

Hele vejen gennem uddannelsessystemet møder elever og studerende det skolerelaterede sprog.....
Tysk med sagen i centrum – et interkulturelt projekt om storbyens forandring
Authors: VONSBÆK MERETE
Published: October 2022

Denne artikel drejer sig om et projekt i tyskundervisningen på...
Åbne Sider - Skal grammatikken genopdages?
Authors: JUNGFALK SØRENSEN MARIE
Published: October 2022

En undersøgelse af tilgangen til grammatik i tyskundervisningen på stx
Kronikken - Målrettet sprogundervisning til flersprogede elever
Authors: Paludan Sofie
Published: October 2022

Københavns Private Gymnasium er i skrivende stund Danmarksnyeste gymnasium. De første elever [...]
Kunsten at lære sprog
Authors: Dollerup Jesse-lee Costa , Lindkvist Tanya
Published: October 2022

Hvad sker der, når sproglæring flytter udaf klasseværelset og ind på museet?
Europa-Dansk
Authors: Rechnitzer Vibeke
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Kultur = Nationalkultur?
Authors: Risager Karen
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
"Contemporary European Studies"
Authors: Kornum Lis
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Kulturtræf
Authors: Frederiksen Karen-Margrete
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Evaluering af tidlig engelskundervisning i Danmark
Authors: Søgaard Karoline , Andersen Nicolai
Published: October 2022

Tidlig engelskundervisning er et varmt politisk emne, og i debatten om folkeskolereformen har dette [...]
åbne sider »Brug dine egne ord!«
Authors: Sigsgaard Anna-Vera
Published: October 2022

– hvordan gør man sig legitim som DSA-elev i historieundervisningen?
Midt i en ny læremiddelkultur
Authors: Hermann Mette
Published: October 2022

Læremiddelkulturen er under markant forandring i disse år, hvorman på alle niveauer inden [...]
Mellem børsen og katedralen Produktion af læremidler i et forlagsperspektiv
Authors: Madsen Helle , Deden Helene
Published: October 2022

Om antagelseskriterierHvilke kriterier sætter forlaget for produktion [...]
Skolebogssamlingen på AU Library, Campus Emdrup (DPB)
Authors: Olesen Isabel
Published: October 2022

Den nuværende samling af læremidler tog sin begyndelse, da DanskSkolemuseum blev grundlagt i 1887. Siden blev [...]
Kritisk kulturel bevidsthed i franskfaget
Authors: Thomsen Sine , Verstraete-Hansen Lisbeth
Published: October 2022

En beretning om et fransk-arabisk udviklingsprojekti gymnasiet
Sprogfagene. Adgang til viden om verden
Authors: Risager Karen
Published: October 2022

Jeg læste engang et eller andet sted følgende udtalelse: ”Hvorfor læse tysk når man interesserer sig for Vietnam?” Nu er de to ting: ’at interessere sig for Vietnam’ og ’at læse tysk’ egentlig ikke sammenlignelige størrelser (...)
Sproglige og kulturelle vidensfonde i klasseværelset
Authors: K. Taylor Shelley
Published: October 2022

I sommeren 2015 afløste den ene krise den anden: Den syriske flygtningekrise førte til en flygtningekrise i Europa. Sådanne kriser (...)
Præsentation af hovedtanker i Claude Hagèges bog Contre la pensée unique
Authors: Dahlgreen Birte
Published: October 2022

I det følgende vil jeg præsentere hovedtankerne i Contre la pensée unique (Mod en ensporet tankegang/Kun én måde at tænke på), udgivet på forlaget  (...)
Er dansk tegnsprog et truet sprog?
Authors: Engberg-Pedersen Elisabeth
Published: October 2022

Kronik
Sprog- og kulturmøder gennem telekollaboration
Authors: Fernández Susana S. , Kanareva-Dimitrovska Ana , Marti Natalia Morollón
Published: October 2022

Pædagogiske metoder og målsætninger er under konstant forandring på grund af den eksplosive digitalisering og globalisering af vores samfund. (...)
Det konceptuelle kulturmøde
Authors: Caviglia Francesco , Fernández Susana S. , Levisen Carsten
Published: October 2022

I denne artikel præsenterer vi vores erfaringer med interkulturelt orienteret undervisning, hvor det arrangerede kulturmøde hoved- sageligt foregår via inddragelse af forskellige teoriretninger og be- grebsapparater, hvilket vi her kalder »det konceptuelle kulturmøde«. (...)
Skriveridentitet og skrivepraktikker i elevperspektiv
Authors: Jakobsen Karen Sonne
Published: October 2022

Gymnasieelevers skrivekompetencer er gjort til et indsatsområde i den nye gymnasiereform som træder i kraft sommeren 2017. (...)
Skrivning og læsning i nutidens verden med multimodalitet og sociale medier
Authors: Kress Gunther
Published: October 2022

Der er mange forhold der trænger sig på i den aktuelle sproglærings- og undervisningsverden i Europa. De falder i to kategorier: sociale og kulturelle problemstillinger, og teknologiske problemstillinger. (...)
Innvandrere og flyktningers vei mot arbeidslivet
Authors: Blaker Aud , Pedersen Michael Svendsen
Published: October 2022

Resumé
Innovation på læreruddannelsen
Authors: Rohde Lilian
Published: October 2022

Resumé
Tværsproglige læringsrum
Authors: Katrine Hvidtfeldt Lorentzen Ane , Amrani Charlotte , Krogager Andersen Line
Published: October 2022

Resumé
Undervisningsmål og lærerkvalifikationer i undervisningen i dansk som andetsprog for voksne
Authors: Holmen Anne , Holm Lars
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Europarådskonference om fremmedsprog
Authors: Kornum Lis
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Input - output - interaktion
Authors: Haastrup Kirsten
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Tour'en på tysk
Authors: Svensson Ingrid
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Fremmedsprogene i den nye læreruddannelse
Authors: Søndergaard Jørn-Ulrik
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord
Sprog ta'r tid
Authors: Haastrup Kirsten
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Når elever tænker højt
Authors: Koudahl Kirsten
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
E-mail og e-mailsprog
Authors: Caudery Tim
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Den stærke tradition
Authors: Tornøe Poul
Published: October 2022

Artikel ved rubrikken ”Åbne Sider” i tidsskriftet.
Samarbejde i fransk mellem grundskole og gymnasium
Authors: Dahlgreen Birte , Stork Ida
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Tysk mellem folkeskole og Gymnasium/HF
Authors: Jensen Kjeld Bjerrum
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Pendling mellem sprogundervisning og danske miljøer
Authors: Nielsen Annie
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Anmeldelse af Studier i dansk som andetsprog
Authors: Gimbel Jørgen
Published: October 2022

Anmeldelse:

Anne Holmen, Karen Lund: Studier i dansk som andetsprog, Akademisk Forlag, 1999.
Grund til bekymring?
Authors: Bakmand Bente
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Evaluering af interkulturel kompetence
Authors: Byram Michael , Risager Karen
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Interkulturel kompetence som tema
Authors: Petersen Karen Bjerg
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Om tosprogethed og tværkulturel undervisning
Authors: For fremmedsprogspædagogik INFODOK Informations- og dokumentationscenter
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Diverse
Authors: For fremmedsprogspædagogik INFODOK Informations- og dokumentationscenter
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Sproglig mangfoldighed
Authors: Holmen Anne
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Task Force
Authors: Pedersen Michael Svendsen
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Internettet som pædagogisk redskab
Authors: Lehmann Anne
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
En flue på væggen
Authors: Søe Jette
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Videnskabssproglige tekster i tyskundervisningen
Authors: Andresen Martina
Published: October 2022

Artikel ved rubrikken ”Åbne Sider” i tidsskriftet.
Det europæiske sprogår i Danmark
Authors: Vonsbæk Merete
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Dagpressen skrev
Authors: Rise Elsebeth
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Læsningens Lyksaligheder
Authors: Kisch Conrad
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Hold på briller, professionalisme og arbejde
Authors: Pedersen Michael Svendsen
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Den Europæiske Sprogportfolio
Authors: Hirtzel Marianne , Pedersen Michael Svendsen
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Engelsk fra ...?
Authors: Brick-Hansen Aase
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Kan stof- og videnseksplosionen håndteres?
Authors: Rise Elsebeth
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Skaller og kerne
Authors: Jakobsen Karen Sonne
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Virtuelle læringsrum
Authors: Meyer Bente
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Tanker om undervisning i fonetik ved de videregående uddannelser
Authors: Livbjerg Inge
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Litteraturlæsning og mundtlig kompetence i gymnasiet
Authors: Kvist Anna
Published: October 2022

Se kort indholdsbeskrivelse i nummerets forord.
Anmeldelse af Grammatikundervisning - hvorfor og hvordan?
Authors: Moltzen Gitte
Published: October 2022

Anmeldelse:

Lise Hedevang: Grammatikundervisning - hvorfor og hvordan? Danmarks Pædagogiske Universitet, 2003
Should raw machine translation be used for public-health information? Suggestions for a multilingual communication policy in Catalonia
Authors: Pym Anthony , Ayvazyan Nune , Prioleau Jonathan Maurice
Published: October 2022

As Catalonia becomes increasingly multicultural as a result of immigration on many levels, official government communications are received by speakers of numerous different languages. For some languages, this is achieved through the employment of qualified translators. For the non-official languages, however, there is increasing reliance on the use of free online machine translation, explicitly without human correction (“post-editing”). Here we survey the use of Google Translate on the official website of the Catalan health service, focusing on COVID-19 vaccination information in 2021 and 2022. We identify the strategic advantages of machine translation and then survey the nature of the main errors made, some of which border on the incomprehensible and self-contradictory. It is proposed that a multilingual communication policy is needed for the mitigation of errors not just through the judicious use of translation memory software and efficient post-editing, but most especially by writing texts in such a way that the machine translation problems are solved before they appear (“pre-editing”). In the relative absence of policies for non-official languages, strategic planning is required in order to ensure that the benefits of machine translation can work towards a more inclusive society, rather than alienate users who merely see their language being abused.
Notícias de um jornalismo radical
Authors: Gomes Soares Jean Dyêgo
Published: October 2022

O que Foucault entende por jornalismo e como ele se relaciona com a filosofia? Para responder à questão, escrutinamos declarações do autor francês acerca do assunto, especialmente sobre dois personagens: Nietzsche “o primeiro filósofo-jornalista” e Kant “o responsável por introduzir o hoje na filosofia”. Detalhando nuances, pretendemos mostrar em que o pensamento de Foucault se avizinha de um jornalismo radical, e em que deste ele se diferencia.
Nihilism and Mythology.
Authors: Santini Carlotta
Published: October 2022

After the Second World War, German intellectuals who opposed the Nazi regime, faced a crisis of consciousness. They were concerned with a critical analysis, which involved every aspect and even the very essence of their culture. In this contribution, I will turn my attention to some segments of this debate on myth, irrationality and nihilism within the field of classical scholarship and history of religions, approaching as samples the correspondence of three scholars, who are representative for three generations before, during and after WWII: the Nobel Prize winner Thomas Mann, the Hungarian mythologist Karolyi Kerényi and the Italian mythologist Furio Jesi, theorist and critic of the right-wing culture. In the work and reflection of all these authors, Friedrich Nietzsche will play a key role .
Aspectos do niilismo em Nietzsche
Authors: Constâncio João
Published: October 2022

O perspectivismo de Nietzsche defende que o mundo como um todo é “absurdo”, não tem uma meta, um valor, uma finalidade, um sentido, mas não defende que a condução de uma vida humana possa ser outra coisa que não um reger-se por metas, valores, fins, sentidos. Esta distinção é fundamental para que se compreenda que, por um lado, Nietzsche aceita a “verdade do niilismo” — aceita que o mundo é em si mesmo “absurdo”, o mundo não pode ser racionalmente justificado —, mas, por outro, entende que, num determinado tipo de cultura humana, o mundo pode ser justificado “enquanto fenómeno estético”. É esta possibilidade de uma justificação estética do mundo que faz do pensamento de Nietzsche uma “luta contra o niilismo”, na qual não se trata de reduzir todas as metas, valores, fins e sentidos a ilusões subjectivas, mas sim de ousar pensar uma “transvaloração de todos os valores”.
The Psychosocial Impact of Parental Multiple Sclerosis on Children and Adolescents: A Systematic Review
Authors: Haker Michel , Peper Julia , Haagen Miriam , Heesen Christoph , Rahn Anne Christin
Published: October 2022

BACKGROUND

Multiple sclerosis (MS) is a common debilitating neurologic disease that affects mostly young women. This review provides an overview of research on the psychosocial impact of parental MS on children to inform clinicians and support people with MS considering parenthood.

METHODS

A systematic review of the literature was performed by searching the MEDLINE, PsycINFO, and PSYNDEX databases. We included quantitative and mixed-method studies assessing psychosocial outcomes of children with a parent with MS. Studies were screened for eligibility and evaluated for risk of bias.

RESULTS

We screened 608 references, assessed 72 studies in full-text, and included 28 studies in this review. Most of the studies reported on psychosocial adjustment processes, with most results suggesting negative consequences, including difficulties with mood, behavior, or social interaction. Several studies also described associations between children with a parent with MS and increased incidences of psychiatric disorders. Nevertheless, some studies claimed that children with a parent with MS were not more likely to have psychosocial problems compared with children without a parent with MS. A few studies indicated probable positive effects of parental MS, eg potentially increased social competence. Other investigated outcomes were children’s coping skills, early childhood development, body image, and effects on education, and these were unaffected or only slightly affected by having a parent with MS.

CONCLUSIONS

Having a parent with MS has a relevant effect on children. However, the heterogeneous nature and varying quality of the included studies limit the interpretability of these findings. Further research is needed to provide robust evidence.
La inspiración al observar colecciones
Authors:   Universitat Oberta de Catalunya, Massaguer Lluc
Published: October 2022

Septiembre y enero son aquellos meses en los que todo empieza de nuevo, cuando todo el mundo se propone (¡este año sí!) crear nuevos hábitos y lograr aquellos objetivos que cuando pasan quince días ya nadie recuerda. Hay un mercado que conoce bien este fenómeno, y este es el del coleccionismo. Álbumes de cromos, muñecas de porcelana, cohetes que se montan por piezas... ¿Por qué y qué coleccionamos? ¿Creatividad y coleccionismo pueden ir de la mano?
Femcreativas S. XXI: el talento de la mujer en la publicidad que sí da la talla
Authors:   Universitat Oberta de Catalunya, Comesaña Comesaña Angélica , Comesaña Comesaña Patricia
Published: October 2022

Es un hecho que las mujeres siempre hemos sido juzgadas por nuestra talla física (que no intelectual). Curiosamente, talla y talento comienzan ambas por la misma letra, aunque representan dos estereotipos opuestos. La nueva ola de creativas busca justamente lo contrario, ser valoradas por su extraordinario talento XXI. Una talla enorme para unas profesionales que diariamente demuestran estar altamente cualificadas para liderar un sector muy competitivo y dinámico.
Transition Towards Result-Based Agriculture Sector and Climate Targets
Authors: Gancone Agita
Published: October 2022

In the agriculture sector the reduction of greenhouse gases (GHG) is a major challenge, but at the same time it is possible to achieve it with smart reduction measures. The main aim of the Thesis is to develop an integrative decision-making methodology for evaluation of GHG emission reduction measures in the agriculture sector, thus moving towards the result-based agriculture sector and climate neutrality from the perspective of evaluation of climate change mitigation. The Thesis is designed as a set of publications including the main GHG emission problems in the agriculture sector.
Spektrāli efektīvu hibrīdu optisko sakaru sistēmu izveide un novērtējums
Authors: Salgals Toms
Published: October 2022

Promocijas darbā ir aprakstītas viļņu garuma blīvētās WDM šķiedru optiskās sakaru sistēmas, t.i., PON un DCI attīstības novērtējums. Eksperimentāli novērtēts spektrāli efektīvs daudzlīmeņu impulsu amplitūdas modulācijas formātu pielietojumu, lai palielinātu PON, DCI un RoF risinājumu veiktspēju, t.sk. 5G un ne tikai ieviešanai. Novērtēts SDM tehnoloģijas pielietojums spektrāli efektīvas, telpiski kapacitatīvas un viļņu garuma blīvētas ŠOPS sistēmas ieviešanai. Tika izstrādāta spektrāli efektīva nākamās paaudzes optiskā sakaru sistēma milimetru-viļņu radiosignālu pārraidei caur šķiedru mobilajiem sakariem, un jauna hibrīda optiskās šķiedras pārraides sistēmas arhitektūra, kas spēj pārraidīt platjoslas interneta datu pārraidi un radiosignālu pārraidi caur vienu optisko šķiedru. Tiek izstrādāts un pirmo reizi pasaulē tiek prezentēts jauns WGMR Kerr-OFC daudzviļņu gaismas avotu spējīgs nodrošināt 50 Gbit/s datu pārraides ātrumu uz viļņu garumu (datu pārraides rekords konkrētajā pētījuma virzienā).
Methodology for Reliability Assessment of Existing Buildings
Authors: Druķis Pēteris
Published: October 2022

The Thesis has developed a methodology for evaluating the reliability level of buildings in use. The overall reliability of the building is characterized by the global reliability index which allows to quantify and compare the reliability levels of different buildings and, depending on the type of use of the building, determine the lowest permissible level. New methods have been developed in the work – the method of quantitative risk classification of buildings and the method for determining the reliability level of individual structural elements in operation. A large-scale study on the state of existing public buildings in Latvia has also been conducted and the practice of building inspection during operation in Europe has been analysed.
Molecular dynamics study of the effect of temperature on the shock response and plastic deformation mechanism of CoCrFeMnNi high-entropy alloys
Authors: Wen Peng  , Tao Gang  ,   School of Energy and Power Engineering, Nanjing University of Science and Technology, Nanjing 210094, China
Published: October 2022

High-entropy alloys have broad application prospects in aviation,aerospace,military and other fields due to their excellent mechanical properties.Temperature is an important external factor affecting the shock response of high-entropy alloys.Molecular dynamics methods are used to investigate the effect of temperature on the shock response and plastic deformation mechanisms of CoCrFeMnNi high-entropy alloys.The effects of temperature on the atomic volume and the radial distribution function of CoCrFeMnNi high-entropy alloys are studied.Then,the piston method is used to generate shock waves in the sample to research the shock response of CoCrFeMnNi high-entropy alloys.The polyhedral template matching method is used to observe the evolution of atomic-scale defects during the shock compression.The results show that the shock pressure,the shock wave propagation velocity,and the shock-induced temperature rise decrease with the increase of the initial temperature.For example,when piston velocity Up=1.5 km/s,the shock pressure at an initial temperature of 1000 K decreased by 6.7% compared to that at 1 K.Moreover,the shock Hugoniot elastic limit decrease linearly with the increase of temperature.The Hugoniot Up- Us curve of CoCrFeMnNi HEA in the plastic stage can be linearly fitted by the formula Us=c0+sUp.c0 decreases with increasing temperature.With increasing shock intensities,CoCrFeMnNi high-entropy alloys undergo complex plastic deformation,including dislocation slip,phase transformation,deformation twinning,and shock-induced amorphization.At relatively high initial temperature,disordered clusters appear inside CoCrFeMnNi HEA,which together with the BCC structure transformed from FCC and disordered structure are significant dislocation nucleation sources.Compared with other elements,Mn element has the largest proportion (25.4%) in disordered clusters.Due to the large atomic volume and potential energy,large lattice distortion and local stress occur around the Mn-rich element,which provides dominant contribution to shock-induced plastic deformation.At high temperatures,the contribution of Fe element to plastic deformation is as important as that of Mn element.The research results contribute to a deep understanding of the shock-induced plasticity and deformation mechanisms of CoCrFeMnNi high-entropy alloys.
Early life stressful experiences escalate aggressive behavior in adulthood via changes in transthyretin expression and function
Authors: Rawat Rohit Singh , Bhambri Aksheev , Pal Muneesh , Roy Avishek , Jain Suman , Pillai Beena , Konar Arpita
Published: October 2022

Escalated and inappropriate levels of aggressive behavior referred to as pathological in psychiatry can lead to violent outcomes with detrimental impact on health and society. Early life stressful experiences might increase the risk of developing pathological aggressive behavior in adulthood, though molecular mechanisms remain elusive. Here, we provide prefrontal cortex and hypothalamus specific transcriptome profiles of peripubertal stress (PPS) exposed Balb/c adult male mice exhibiting escalated aggression and adult female mice resilient to such aberrant behavioral responses. We identify transthyretin (TTR), a well known thyroid hormone transporter, as a key regulator of PPS induced escalated aggressive behavior in males. Brain-region-specific long-term changes in Ttr gene expression and thyroid hormone (TH) availability were evident in PPS induced escalated aggressive male mice, circulating TH being unaltered. Ttr promoter methylation marks were also altered being hypermethylated in hypothalamus and hypomethylated in prefrontal cortex corroborating with its expression pattern. Further, Ttr knockdown in hypothalamus resulted in escalated aggressive behavior in males without PPS and also reduced TH levels and expression of TH-responsive genes (Nrgn, Trh, and Hr). Escalated aggressive behavior along with reduced Ttr gene expression and TH levels in hypothalamus was also evident in next generation F1 male progenies. Our findings reveal that stressful experiences during puberty might trigger lasting escalated aggression by modulating TTR expression in brain. TTR can serve as a potential target in reversal of escalated aggression and related psychopathologies.
Neuronal temperature perception induces specific defenses that enable C. elegans to cope with the enhanced reactivity of hydrogen peroxide at high temperature
Authors: Servello Francesco A , Fernandes Rute , Eder Matthias , Harris Nathan , Martin Olivier MF , Oswal Natasha , Lindberg Anders , Derosiers Nohelly , Sengupta Piali , Stroustrup Nicholas , Apfeld Javier
Published: October 2022

Hydrogen peroxide is the most common reactive chemical that organisms face on the microbial battlefield. The rate with which hydrogen peroxide damages biomolecules required for life increases with temperature, yet little is known about how organisms cope with this temperature-dependent threat. Here, we show that Caenorhabditis elegans nematodes use temperature information perceived by sensory neurons to cope with the temperature-dependent threat of hydrogen peroxide produced by the pathogenic bacterium Enterococcus faecium. These nematodes preemptively induce the expression of specific hydrogen peroxide defenses in response to perception of high temperature by a pair of sensory neurons. These neurons communicate temperature information to target tissues expressing those defenses via an insulin/IGF1 hormone. This is the first example of a multicellular organism inducing their defenses to a chemical when they sense an inherent enhancer of the reactivity of that chemical.
Deep mutational scanning and machine learning reveal structural and molecular rules governing allosteric hotspots in homologous proteins
Authors: Leander Megan , Liu Zhuang , Cui Qiang , Raman Srivatsan
Published: October 2022

A fundamental question in protein science is where allosteric hotspots – residues critical for allosteric signaling – are located, and what properties differentiate them. We carried out deep mutational scanning (DMS) of four homologous bacterial allosteric transcription factors (aTFs) to identify hotspots and built a machine learning model with this data to glean the structural and molecular properties of allosteric hotspots. We found hotspots to be distributed protein-wide rather than being restricted to ‘pathways’ linking allosteric and active sites as is commonly assumed. Despite structural homology, the location of hotspots was not superimposable across the aTFs. However, common signatures emerged when comparing hotspots coincident with long-range interactions, suggesting that the allosteric mechanism is conserved among the homologs despite differences in molecular details. Machine learning with our large DMS datasets revealed global structural and dynamic properties to be a strong predictor of whether a residue is a hotspot than local and physicochemical properties. Furthermore, a model trained on one protein can predict hotspots in a homolog. In summary, the overall allosteric mechanism is embedded in the structural fold of the aTF family, but the finer, molecular details are sequence-specific.
The wtf meiotic driver gene family has unexpectedly persisted for over 100 million years
Authors: De Carvalho Mickaël , Jia Guo-Song , Nidamangala Srinivasa Ananya , Billmyre R Blake , Xu Yan-Hui , Lange Jeffrey J , Sabbarini Ibrahim M , Du Li-Lin , Zanders Sarah E
Published: October 2022

Meiotic drivers are selfish elements that bias their own transmission into more than half of the viable progeny produced by a driver+/driver− heterozygote. Meiotic drivers are thought to exist for relatively short evolutionary timespans because a driver gene or gene family is often found in a single species or in a group of very closely related species. Additionally, drivers are generally considered doomed to extinction when they spread to fixation or when suppressors arise. In this study, we examine the evolutionary history of the wtf meiotic drivers first discovered in the fission yeast Schizosaccharomyces pombe. We identify homologous genes in three other fission yeast species, S. octosporus, S. osmophilus, and S. cryophilus, which are estimated to have diverged over 100 million years ago from the S. pombe lineage. Synteny evidence supports that wtf genes were present in the common ancestor of these four species. Moreover, the ancestral genes were likely drivers as wtf genes in S. octosporus cause meiotic drive. Our findings indicate that meiotic drive systems can be maintained for long evolutionary timespans.
Antibacterial T6SS effectors with a VRR-Nuc domain are structure-specific nucleases
Authors: Hespanhol Julia Takuno , Sanchez-Limache Daniel Enrique , Nicastro Gianlucca Gonçalves , Mead Liam , Llontop Edgar Enrique , Chagas-Santos Gustavo , Farah Chuck Shaker , de Souza Robson Francisco , Galhardo Rodrigo da Silva , Lovering Andrew L , Bayer-Santos Ethel
Published: October 2022

The type VI secretion system (T6SS) secretes antibacterial effectors into target competitors. Salmonella spp. encode five phylogenetically distinct T6SSs. Here, we characterize the function of the SPI-22 T6SS of Salmonella bongori showing that it has antibacterial activity and identify a group of antibacterial T6SS effectors (TseV1–4) containing an N-terminal PAAR-like domain and a C-terminal VRR-Nuc domain encoded next to cognate immunity proteins with a DUF3396 domain (TsiV1–4). TseV2 and TseV3 are toxic when expressed in Escherichia coli and bacterial competition assays confirm that TseV2 and TseV3 are secreted by the SPI-22 T6SS. Phylogenetic analysis reveals that TseV1–4 are evolutionarily related to enzymes involved in DNA repair. TseV3 recognizes specific DNA structures and preferentially cleave splayed arms, generating DNA double-strand breaks and inducing the SOS response in target cells. The crystal structure of the TseV3:TsiV3 complex reveals that the immunity protein likely blocks the effector interaction with the DNA substrate. These results expand our knowledge on the function of Salmonella pathogenicity islands, the evolution of toxins used in biological conflicts, and the endogenous mechanisms regulating the activity of these toxins.
Kunnskapsoppsummering og klassifisering av tiltaket: Skilsmissegrupper (2. utg.)
Authors: Rasmussen Lene-Mari P. , Christiansen Øivin , Reedtz Charlotte
Published: October 2022

Bakgrunn
Skilsmissegrupper er et helsefremmende og forebyggende gruppebasert tiltak for barn og unge som tilbys gjennom skolen, primært via helsesykepleier. Målet med tiltaket er å gi barn som opplever samlivsbrudd i familien en arena for å møte andre barn som har lignende erfaringer, å kunne snakke med andre enn foreldrene om hvordan det oppleves, og å bli bedre i stand til å håndtere (den nye) hverdagen. Tiltaket ble utviklet tidlig på 2000-tallet av to helsesykepleiere, og drives i dag gjennom organisasjonen Voksne for Barn.
Metode
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.
Resultater
Resultatene i denne kunnskapsoppsummeringen består av en vurdering av tiltakets beskrivelse, foreliggende studier, og implementeringskvalitet. Skilsmissegrupper er godt beskrevet og bygger på et kjent teorigrunnlag. Videre bygger denne kunnskapsoppsummeringen på tre kvalitative studier som har undersøkt både ungdommenes og utøvernes opplevelse med gruppene, samt en evalueringsrapport, men det foreligger ingen nordiske effektstudier av tiltaket hvilket gjør det vanskelig å si noe om effekten av tiltaket.
Konklusjon
Skilsmissegrupper klassifiseres på evidensnivå 2 – Teoretisk begrunnet tiltak
Use of Free Gingival Graft and PRF to Increase the Width of the Attached Gingiva: A Novel Approach
Authors: Masurkar Deepika Ajit , Jaiswal Priyanka , Kale Bhairavi , Rathod Aishwarya
Published: October 2022

Inadequate width of attached gingiva can lead to difficulty in maintaining oral hygiene, can cause recession and if the patient is undergoing orthodontic treatment the bands and brackets might get engrossed in the buccal mucosa. Therefore, increasing the width of attached gingiva is necessary. A 19-year-old female patient who was referred from the Department of Orthodontics for impinging of bands into gingiva which was identified to be because of in adequate width of attached gingiva. Horizontal incision was given at mucogingival junction from 34 to 44 region. Full-thickness flap was raised till the required vestibular depth recipient site is required. Free Gingival Graft (FGG) of size 15×10 mm in size was harvested from left palatal mucosa from distal to 24 to mesial to 26 region. Harvested FGG was sutured from 32 to 42 region in the recipient site. Platelet Rich Fibrin (PRF) membrane was prepared using patients own blood and this membrane was sutured at 33 and 43 region at the recipient site. An aluminium foil was kept at the donor site and above the membrane at the recipient site on which periodontal pack was given. After 21 days of healing, the width of attached gingiva increased from 2 mm at baseline to 8 mm. According to visual analog scale, mild pain was felt by the patient and no difference in the colour was seen at both recipient and donor site at 21 days after surgery. Use of FGG and PRF helps to achieve improved results for increase width of attached gingiva.
Factory Production Process of Shiitake Mushrooms
Authors: Dong Rong , Cai Peifang
Published: October 2022

In recent years, edible mushrooms factory production has been developing rapidly, equipped with a multitude of facilities and equipment supporting the shiitake mushroom stick cultivation mode, which can fully realize the whole process of mechanized operation. This paper introduces the main processes of shiitake mushroom factory production, which include shiitake mushroom stick making process, stick sterilization process, cooling inoculation process, solid and liquid strain cultivation process and mushroom emergence process. Factory production of shiitake mushrooms improves product quality and production efficiency, reduces the economic cost of cultivation, which is essential for the future prosperous development of shiitake mushroom industry.
Ethnobotanical, Phytochemical and Pharmacological Studies of Capsicum annuum L. (Solanaceae) in the Healing of Traumatic Wounds (Case of Eye Wounds): A Mini Review
Authors: Ngalamulume Henry Beya , Divengi Jean-Paul Nzambi , Mbuyi Patience Lunkondo , Assumani Idrissa Zabo , Mukeba Florent Biduaya , Mutwale Paulin Kapepula , Kayembe Jean Pierre Kayembe
Published: October 2022

Several studies have shown that the extracts of Capsicum annuum L. have been used in the treatment of various ailments (fever, colds, chest pain, cancer, cough, sore throat, toothache, cardiovascular disease, diabetes, wound healing Rheumatic wounds and inflammations, etc. It also inhibits bacterial growth and clumping of blood platelets.

According to various bibliographical sources, Capsicum annuum L. is an excellent source of phytochemicals such as carotenoids, ascorbic acid, flavonoids, tocopherols and capsaïcinoïds which are very important in the prevention of chronic diseases mentioned above. This richness of the pigment in the possession of a diversity of bioactive molecules would constitute an excellent remedy in the healing of traumatic wounds of the eye and we predict that these compounds would prevent the development of cataracts of the eye. A situation contrary to the healing of eye wounds based on tetracycline and chloramphenicol, the healing of which leads to the formation of cataracts, the main cause of extensive eye operations aimed at "the destruction of this organ" d 'capital importance.

Research methods: In this Bibliographic survey, our approach revolved around the literature on the Capsicum annuum L plant. Several results were retrieved from the Articles, Memoirs and Theses having addressed the study of Capsicum annuum L. And these results were retrieved using Google which was considered our search engine. In summary, it is the documentary technique that was at work.
Effect of Different Date of Sowing on Rice (Oryza sativa L.) Seedling Blight Disease under Nursery Conditions
Authors: Patoliya Parasant Rajeshbhai , Nath Kedar
Published: October 2022

Aims:  The main objective of this study was to find appropriate suitable period for raising rice nurseries to summer cultivation for improved seed germination and reduced seedling mortality in nursery under South Gujarat conditions of India.

Study Design: Large Plot Technique.

Place and Duration of Study: Regional Rice Research Station, Navsari Agricultural University, Vyara, Gujarat (Zone II, Agro ecological situation V), India during 2020-21.

Methodology: Seeds of rice variety GNR-3 was sown in raised bed nursery at 10 days interval from 20 November, 2020 to 9 January, 2021 under open field condition. .Frequently light irrigation gave to maintained soil moisture. Per cent seed germination (%), seedling mortality, root and shoot length (cm) were recorded at 21 days after sowing (DAS) and 35 DAS.

Results: the present studied revealed that highest seed germination 62.83 per cent was observed in seeds was sown on 30th November. Whereas minimum seedling mortality 10.03 percent was recorded in seeds sown on 20th November, at 21 days after sowing (DAS).While, maximum seedling mortality, 39.93 per cent was recorded in seed sown on 9th January. Similarly, at 35 DAS, minimum seedling mortality 17.25 per cent was recorded in seeds sown on 20th November. Maximum seedling mortality (43.76%) was observed in seeds sown on 9th January. Maximum root length 11.30 cm was recorded in seeds sown on 9th January. Maximum shoot length 26.6 cm was observed in seeds sown on 30th November.

Conclusion: Highest per cent seed germination, minimum seedling mortality and good root and shoot growth were observed in rice nursery sown between 20-30 November.
3D Printing in Medicine; Application in Intracranial Tumours in Southern Nigeria
Authors: Ikponmwosa Morgan , Ogunsemoyin Ayodele Olugbenga , Moemenan Onyekachi Okechukwu , Ezeigwe Obinna , Darko Yaw Barimah
Published: October 2022

Background: The pituitary gland is a small bean-shaped gland situated at the base of the brain. Pituitary-based tumors are neuroendocrine tumours affecting the pituitary gland. Imaging of the pituitary gland involves the use of computed tomography and magnetic resonance imaging. 3D reconstruction of data from CT images can be converted into 3D and then made into a live anatomical model using a 3D printer.

The objective and aim of this study are to demonstrate that findings from CT scan images can be used to generate 3D printed specific models for patients and clinicians.

Methods: Patient-specific models for three clinical cases were segmented using a segmentation application to isolate the mass and the bone. The process involved image acquisition from a cross-sectional imaging to segmentation of the acquired DICOM image into a 3D model followed by file and model correction for final print, this is then followed on to slicing with the selection of 3D printing material as well as appropriate settings, this is then concluded with the actual print, print accuracy, and cost analysis.

Results: Segmentation of the region of interest took about 45 to 90 minutes with the majority of the time spent on segmentation of the pituitary. Printing of models was done into sections as the skull and mass were printed separately. The times required spanned from 20-40 minutes and 4-9 hours for the mass and skull base respectively. Print accuracy was less than 1.7mm with the total cost of printing a model was less than $50.

Conclusion: This study showed steps in 3D printing anatomical models from a computed tomogram of patients with brain lesions.
Effect of Large Openings on Bending Strength of Reinforced Concrete Beam
Authors: Makanju Olanitori, Lekan , Philips Otuaga, Moses , Ayodeji Oso, Ifedotun
Published: October 2022

At the design stage of beams, openings for service ducts are rarely taking into consideration. The introduction of openings for service ducts have negative effects on the strength characteristics of beams, hence the focus of this research is to investigate the effect of large service openings on the ultimate load of reinforced concrete beams produced from locally available materials. A total of ten beams were cast using 20.8 N/mm² concrete grade. The cross-sectional dimensions of the beams were 100mm x 150mm and 1000 mm length, with effective span of 750 mm. The tested beams consisted of two control beams. The experimental beams consisted of eight beams, four of the beams were with 40 mm service openings (with two beams having openings at the centre and two beams having openings at the supports) and the other four beams had 50 mm service holes (with two beams having openings at the centre and two beams having openings at the supports). The reinforced concrete beams were cured by covering it with wet cloths and tested at 28th day. The control beams and experimental beams were subjected to point loads at the beam centre to study the effect of the openings on the ultimate load. The average actual ultimate load for the experimental beams with 40 mm openings at the supports (TII) and centre were (TIII) were 49.48 kN and 63.28 kN respectively, representing 28% increase in the ultimate load when opening is moved from support to the centre of the beam. Also there is 45% increase in the average actual ultimate load for the experimental beams with 50 mm, when the opening is moved from supports (TIV) to the centre (TV). The average actual ultimate load for the control beams (TI) was 63.88 kN, while the estimated ultimate loads for control and the experimental beams was 70.13 kN, which shows that the estimated ultimate load is about 10% higher than the actual ultimate load. The openings placed at the supports of beams have more strength reducing effect on the ultimate load, when compared with the openings placed at the centre of the beams.
Appropriate Technology and Design: A Solution for Sustainable and Affordable Housing Delivery in Major Cities of Ghana
Authors: Tekpe Emmanuel , Ansah Samuel Kwame , Akomah Benjamin Boahene
Published: October 2022

Appropriate technology and design for housing delivery undoubtedly has abundant cost benefit and other advantages. However, the acceptance of its usage and application for sustainable and affordable housing delivery is rare. Appropriate technology supports and enhances good life without compromising the earth’s ecosystem and the prospects of later generations. It is energy efficient, environmentally sound, and it is been controlled by the local community with local available materials. Appropriate housing design on other hand, focuses on the engineering and architectural perspective of a structure that supports sustainable construction and development. The paper aimed at determining the extent to which appropriate technologies and designs are currently employed in addressing housing sustainability and affordability in Ghana. Questionnaire survey was used for the data collection. The study was conducted in Accra, Takoradi and Cape Coast of Ghana within the period of 5 Months.  In total, 110 questionnaires were distributed among Building and Construction Professionals and Self- Built House Owners. Out of the number distributed, 56 were retrieved for analysis. Data was analyzed using descriptive statistics. The findings of the study established that, hydrafoam, adobe bricks technology, timber homes technology, and wattle and daub technology were considered the most used and acceptable appropriate technologies for sustainable and affordable housing delivering. The findings of the study also revealed that, the extent to which appropriate technologies and designs have been adopted in major cities in Ghana is low. This implies that less emphasis is placed on the use of appropriate technology and design in resolving sustainable and affordable housing issues in major cities. It is therefore, suggested that, government and stakeholders mainstream the use of appropriate designs and technologies for sustainable and affordable delivery. Consequently, stakeholders should help change the perception of Ghanaians towards the adoption of appropriate technologies and designs for sustainable and affordable housing delivery.
A New Data Gathering Exponential Type Ratio Estimator for the Population Mean
Authors: Ganie Zahoor A. , Tarray Tanveer A. , Khalid–Ul–Islam–Rather .
Published: October 2022

In this article we proposed a new data gathering exponential ratio type estimator for the estimation of finite population mean under systematic sampling .The mean square error of the suggested estimator is computed up to the first degree of approximation and we find suggested estimator is efficient as compared with existing estimators. Furthermore this result is supported by numerical examples as well.
Bioinspired Composite Hydrogel‐Coated Stainless Steel Screen for Efficient and Stable Gravity‐Driven Oil–Water Separation
Authors: Xiao Wenqian , Li Hong , Yang Haocheng , Shu Yue , Tu Tianyi , Li Bo , Liao Xiaoling
Published: October 2022

The reasonable and efficient treatment of oily wastewater has attracted wide attention. Herein, a composite hydrogel‐modified filter screen, inspired by fish scales and marine mussels, is prepared via layer‐by‐layer modification to separate oil–water mixture even in harsh environments. First, a stainless steel filter screen is coated by a layer of silicon dioxide (SiO2) microspheres by the vapor deposition of polydimethylsiloxane. Then, a SiO2@polydopamine‐polyacrylamide composite hydrogel (SiO2@P–PGel)‐modified screen is prepared by dipping the screen into a prepolymer solution. Due to the special wettability and micronanostructures, the stable and high efficient water permeation in the air and oil repellency in water are achieved by the screen. A very effective oil–water separation rate of over 99% can be achieved for various types of oil–water mixtures. The separation efficiency and water flux remain stable even after 70 cycles. Another significant feature of the innovative screen is that it displays excellent underwater superoleophobicity in very salty, acidic, and alkaline solutions, suggesting that the screen has excellent oil–water separation performance and stability, even in corrosive aqueous media. This innovative screen is a potentially attractive candidate for the treatment and recovery of oily wastewater due to its high efficiency and stability.