bluuebunny/crossref_metadata_2025 huggingface dataset:
A State of De-Stress: Examining the Relationship Between Subjective Well-Being, Self-Compassion, and Empathy
Authors: Hablado Kurt , Clark Mitchell
Published: June 2020

University can be a period of stress caused by academic, social, or personal demands. Yet most are able to rise above the adversity and grow from their experiences. Research on stress has found that a negative association exists with subjective well-being broadly conceptualized as life happiness (Denovan & Macaskill, 2017; Zhang, 2009). There are also positive relationships demonstrated between self-compassion and empathy with subjective well-being (Bluth et al., 2016; Thomas et al., 2007). This study examined the relationship between perceived stress and subjective well-being in a non-clinical university population. The study also examined the relationship between stress and subjective well-being, and how that relationship was moderated by the self-compassion and mediated by empathy.
Ethnic Memory And Historical Injustices In Nigeria
Authors: Olusegun Atere Clement
Published: June 2020

It is a known fact that not few Nigerians believed that the country has committed atrocities against her citizen and this has caused mutual suspicion, deep divisions, inter-ethnic wrangling, and unending disputations in this ethnically and geographically diverse nation.

The aim of this paper is to provide fresh insight on the causality of the deep mistrust and mutual suspicion among the various ethnic groups which in turn has caused the Nigeria nation much needed unity. The paper argued that recurring memorialization of unresolved historical injustices has been a potent poison to the glowing of communal and organic wellbeing of the nation.

The paper concluded that the government must redress the past historical injustices, explore how Nigerians together can search for common memories to meet present needs,  and allow the various ethnic group to come to terms with their past. The paper recommended new Truth and Reconciliation Commission
Interferences in the measurement of circulating phosphate: a literature review
Authors: Molinaris Valentina , Bianchetti Mario G. , Milani Gregorio P. , Lava Sebastiano A.G. , Bruna Roberto Della , Simonetti Giacomo D. , Faré Pietro B.
Published: June 2020

Background

Inorganic phosphate in blood is currently determined by the reaction with molybdate. This report aims at reviewing conditions underlying spuriously altered levels of circulating inorganic phosphate.

Content

A systematic search of the Excerpta Medica, the National Library Database and the Web of Science database was conducted without language restriction from the earliest publication date available through January 31, 2020.

For the analysis, 80 reports published in English (n = 77), French (n = 1), German (n = 1) and Spanish (n = 1) were retained. Well-documented pseudohyperphosphatemia was observed in individuals exposed to liposomal amphotericin, in patients affected by a gammopathy, in patients with hyperlipidemia and in patients with hyperbilirubinemia. An unexplained elevated inorganic phosphate level sometimes provided a clue to the diagnosis of a gammopathy. Well-documented cases of pseudohypophosphatemia were observed in patients on large amounts of intravenous mannitol. Finally, pseudohypophosphatemia was occasionally observed on treatment with liposomal amphotericin and in patients with a gammopathy.

Outlook

In order to avoid unnecessary testing and treatment, the phenomenon of spuriously altered inorganic phosphate should be recognized. An unexplained hyperphosphatemia may provide a clue to the diagnosis of a gammopathy or a severe hyperlipidemia.
The role of sex and gender in search behavior for political information on the internet
Authors: Kessler Sabrina Heike , Langmann Klara
Published: June 2020

Previous studies have emphasized a person’s biological sex as a factor which influences online search behavior. This study aims to investigate how people (N = 44 students) search online for political information (N = 220 search tasks) and if gendered online search exists. We examined online search behavior via eye tracking while the participants searched for information about political party positions on the Internet. A content analysis of the eye tracking data followed and was evaluated with a special focus on the role of biological sex and social gender, and the relationship of both factors with other variables, such as self-reported prior political knowledge, political interest, and Internet skills (via an online survey). The results accord with previous studies in that the sex influences the online search process. However, this relationship was partially mediated by self-reported political interest and prior knowledge. This outcome calls for a more critical use of the sex variable in reference to political online search behavior, and the inclusion of sex and gender related variables.
Migratory movements in the press of Spanish-speaking countries (2017)
Authors: Salas Luis Guerra , Sánchez María Elena Gómez
Published: June 2020

The aim of this article is to analyze journalistic texts on migratory movements appeared on the main newspapers of Spanish-speaking countries along 2017. The focus is put on the subjects that the newspapers highlight, the regions selected and the linguistics elections being made. The research has a multidisciplinary approach that uses the concept of representation, as being used in linguistics pragmatics and cultural anthropology. We use the database Factiva® as the starting point to collect the journalistic pieces that we use for our analysis. The search has been refined using linguistic, contextual, geographic and chronological criteria. Two sub-corpora have been built with the texts obtained through the search. One focuses strictly on Spanish press and the second one is related to the Hispanic area (seven newspapers have been chosen to build this corpus, and each one of them represents one of the seven ample dialectal areas of Spanish language). The qualitative analysis is based on the key words of each of these sub-corpora; such key words are stablished from a text-mining technique that offers the most relevant words and sentences of the first 100 texts obtained through every specific search.
Therapeutic role of metformin and troglitazone to prevent cancer risk in diabetic patients: evidences from experimental studies
Authors: Haq Muhammad Ejaz ul , Akash Muhammad Sajid Hamid , Rehman Kanwal , Khurshid Mohsin
Published: June 2020

Objectives

It is evident from literature that individual with diabetes mellitus is more prone to develop cancer as compared to non-diabetic one. We aimed to highlight the risk factors that trigger the tumor formation in diabetic individuals and collect evidences regarding the preventive role of anti-diabetics in cancer.

Content

A comprehensive literature was searched in English language using electronic databases including PubMed, ScienceDirect, Medline, Scopus and Embase.

Summary and outlook

Antidiabetic drugs notably metformin and troglitazone, exhibit anticancer effects. Metformin targets energy sensor pathway i. e., AMPK/mTOR which is controlled by LKB1. Whereas. troglitazone activates PPARϒ that modulate the transcription of insulin responsive gene which is essential for lipid and glucose metabolism. Adipocytes are highly expressed with PPARɣ which induce differentiation and regulate adipogenesis. Ligand-driven expression of PPARɣ in myoblast and fibroblast cell lines produces adipocyte differentiation in breast cancer. Prostate cancer that expresses PPARɣ may be suppressed by troglitazone and retinoid which inhibit their proliferation and initiate differentiation. The findings summarized here show that metformin and troglitazone may have the ability to inhibit the cancer cell proliferation via involvement of molecular pathways. This therapeutic intervention will help to control the progression of cancer in diabetic patients.
Development of a trunk motor paradigm for use in neuroimaging
Authors: Saunders Elizabeth , Clark Brian C. , Clark Leatha A. , Grooms Dustin R.
Published: June 2020

The purpose of this study was to quantify head motion between isometric erector spinae (ES) contraction strategies, paradigms, and intensities in the development of a neuroimaging protocol for the study of neural activity associated with trunk motor control in individuals with low back pain. Ten healthy participants completed two contraction strategies; (1) a supine upper spine (US) press and (2) a supine lower extremity (LE) press. Each contraction strategy was performed at electromyographic (EMG) contraction intensities of 30, 40, 50, and 60% of an individually determined maximum voluntary contraction (MVC) (±10% range for each respective intensity) with real-time, EMG biofeedback. A cyclic contraction paradigm was performed at 30% of MVC with US and LE contraction strategies. Inertial measurement units (IMUs) quantified head motion to determine the viability of each paradigm for neuroimaging. US vs LE hold contractions induced no differences in head motion. Hold contractions elicited significantly less head motion relative to cyclic contractions. Contraction intensity increased head motion in a linear fashion with 30% MVC having the least head motion and 60% the highest. The LE hold contraction strategy, below 50% MVC, was found to be the most viable trunk motor control neuroimaging paradigm.
Experiences of Social Entrepreneurship Pioneers in Lithuania
Authors: Adomaitytė-Subačienė Ieva , Girkontaitė Agnė , Petružytė Donata , Šumskienė Eglė
Published: June 2020

The phenomenon of social entrepreneurship is sufficiently well-researched abroad since the end of the 20th century. Nevertheless, it is quite a new and under-researched subject in Lithuanian academic discourse. The goal of this article is to explore the experiences of pioneers of social entrepreneurship in Lithuania, the way they create and develop the model of social entrepreneurship. The first half of the article discusses various concepts of social entrepreneurship, its historical development, connections with corporate social responsibility and its purpose in contemporary societies. The second part describes the authentic experiences of being the icebreakers of social business practices in bureaucratic system. Results are based on semi-structured qualitative interviews, conducted in autumn 2018 - spring 2019, with 14 social entrepreneurs in Lithuania. The analysis was done following the approach of grounded theory. The research shows, that social entrepreneurs experience various challenges while cooperating with governmental institutions or municipalities while searching for suitable funding models and experiencing ignorance from society in general. Nevertheless, they still engage in these activities with the help and support of an emerging community of active like-minded social entrepreneurs, whose support is essential for the existence and development of social entrepreneurship in Lithuania.
Electrophysiology’s Identity Crisis: What our Clinical Trials Do and Do Not Say About Us
Authors: Callans David J , Reynolds Matthew , Zimetbaum Peter J
Published: June 2020

Although it has not always been this way, the impact of large, randomised clinical trials in electrophysiology is limited, at least compared with other disciplines in cardiology. This has been particularly true regarding procedural aspects of our field: successful randomised trials are rare and observational trials are small and typically without a proper active control group. In this article, the authors examine the reasons behind this circumstance, which include underinvestment from funding sources; lack of consensus on procedural endpoints; lack of consensus on techniques; and a therapeutic bias in favour of procedural intervention that stands in the way of investigator equipoise. Together, these factors have created a scientific culture dominated by small-scale, siloed, observational research and unwillingness to collaboratively advance the field with consensus and prospective trials. The authors feel that it is increasingly urgent to improve the scientific basis for clinical practice and explore strategies to accomplish this goal.
A CONSTRUÇÃO DO ENSINO MÉDIO INTEGRADO: CONTRIBUIÇÕES A PARTIR DE UMA PROPOSTA DE FORMAÇÃO CONTINUADA NO IFSUL - CÂMPUS PELOTAS
Authors: Cardoso Ticiana Cougo , Hammes Itamar Luís , Both Joseline Tatiana
Published: June 2020

O presente trabalho é fruto da pesquisa realizada no Mestrado Profissional em Educação Profissional e Tecnológica - PROFEPT. A investigação teve como propósito promover a discussão sobre a construção curricular do Ensino Médio Integrado. O recorte proposto constituiu-se no desenvolvimento e avaliação de uma proposta de formação continuada na escola, reunindo professores que atuam em um dos cursos técnicos integrados do IFSul – Câmpus Pelotas. As análises realizadas apontaram para a necessidade da compreensão crítica do mundo do trabalho pelo professor da educação profissional, bem como da necessidade de romper com a fragmentação de conteúdos e buscar formas de articulação dos conhecimentos de modo a gerar aprendizagens significativas. Concluiu-se pela importância da formação e da integração dos professores para a consolidação do currículo integrado, através de espaços coletivos de estudo, debate, troca de experiências e avaliação da prática pedagógica.
Tarih Metodolojisi Açısından Türkiye’deki Din Eğitimi Tarihi Çalışmaları Üzerine Bir Değerlendirme
Authors: DOĞAN Recai
Published: June 2020

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Differential diagnosis and morphological and functional characteristics of atrial myxoma
Authors: Sukhorukova O. A. , Parno A. A. , Mayer V. V. , Ali-Riza A. E. , Semichev E. V.
Published: June 2020

Right atrial myxoma is one of the rare diseases in cardiology practice. It is accompanied by an unclear clinical picture, and in most cases is asymptomatic and is an incidental finding. The article is devoted to the clinical observation of primary cardiac tumor and the difficulties of its differential diagnosis.

Patient T, 58 years old, was hospitalized in a respiratory medicine center with complaints of cough with viscous sputum, weakness, fatigue, loss of appetite, shortness of breath on exertion, weight loss and sweating at night. The preliminary diagnosis was an exacerbation of chronic bronchitis. Then a space-occupying mass in the right atrium was revealed. Computed tomography imaging identified a bilateral pulmonary embolism. In the cardiac surgery department, surgical removal of the right atrial myxoma was performed.

The diagnosis of right atrial myxoma was established by echocardiography, confirmed macroscopically during surgery, and then by histological verification.
Towards quadruple therapy for heart failure with reduced ejection fraction: DAPA-HF secondary analysis data
Authors: Kobalava Zh. D. , Medovchshikov V. V. , Yeshniyazov N. B.
Published: June 2020

Patients with heart failure with reduced ejection fraction (HFrEF), despite optimal evidence-based treatment, have a high residual risk of adverse outcomes. The favorable results of studies on cardiovascular safety and the effectiveness of sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with type 2 diabetes (T2D), including outcomes associated with heart failure, were the reason for studying the effectiveness in patients with HFrEF regardless of the T2D status. For the first time in the DAPA-HF study, the SGLT2 inhibitor dapagliflozin in patients with HFrEF showed a positive effect on hard endpoints. Data of the secondary analysis confirmed the effectiveness of dapagliflozin regardless of the T2D status, therapy, age, and quality of life. The results of DAPA-HF have become a serious statement for changing the standards of the guideline-recommended therapy of HFrEF.
Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registry
Authors: Mikhaylov E. N. , Korobchenko L. E. , Bayramova S. A. , Kharats V. E. , Kachalkova O. N. , Dmitriev A. Yu. , Batalov R. E. , Morgunov D. P. , Silin I. A. , Aleksandrovskiy A. A. , Kryzhanovskiy D. V. , Romanov A. B. , Pokushalov E. A. , Lebedev D. S. , Kuznetsov V. A. , Kolunin G. V. , Zamanov D. A. , Chetverikov S. Yu. , Yashin S. M. , Popov S. V. , Ivanitsky E. A. , Gorkov A. I. , Mamchur S. E. , Bazaev V. A.
Published: June 2020

Aim. Catheter ablation (CA) is an effective approach for rhythm control in atrial fibrillation (AF), however antiarrhythmic therapy (AAT) remains important. There is a lack of data about long-term AAT use after CA. This study evaluates AAT after CA for AF.

Material and methods. In 2012-2016, EURObservational Research Programme of Atrial Fibrillation Ablation Long-Term (EORP AFA L-T) registry was conducted, which included 476 Russian patients (57,1% — men; mean age — 57,1±8,7 years). The follow-up after CA was 12 months (available in 81,9% of patients). The use of AAT was evaluated prior to hospitalization, during hospitalization for CA, as well as at 3, 6 and 12 months of follow-up.

Results. Prior to CA, 439 (92,2%) patients received AAT During CA, 459 (96,4%) patients were treated with AAT. After CA, AAT was used by 463 (97,3%), 370 (94,8%), and 307 (78,7%) patients at 3, 6 and 12 months of follow-up, respectively. There was no arrhythmia recurrence in 187 (47,9%) subjects. Among these patients, 40 (21,4%) received class IC or III AAT. The peak of AAT use was found for class IC agents within 3 months after CA (P<0,05), while for other drugs this trend was not observed. There were no factors associated with AAT usage in patients without arrhythmia recurrence after CA. A positive correlation of arrhythmia non-recurrence with a minimum number of previously used antiarrhythmic agents was revealed (RR=0,85; 95% CI 0,73-0,98; P=0,03).

Conclusion. The frequency of AAT use after AF ablation is significantly reduced. However, there is a cohort of patients without documented arrhythmia recurrence still receiving AAT, which requires special attention of physicians. There were no clinical predictors of continued AAT in subjects without arrhythmia recurrence.
Automation Factors Influencing the Operation of IoT in Health Institutions: A Decision Support Methodology
Authors: Oddershede Astrid M. , Macuada Claudio J. , Quezada Luis E. , Montt Cecilia A.
Published: June 2020

Health institutions are adopting new technologies for their processes through automation by means of the concept of "Internet of Things" (IoT). Hence, offering innovative tools, applications and technology for the collection of key data and information, which is then integrated and consolidated, covering the different systems and their collaborators. The necessity of receiving quality medical services is essential in the public Policy of any country. The increasing demand for having an adequate number of medical specialists, pharmacies and medications stock, dental and mental health coverage and other, together with the minimization of the waiting list and patient care time have been a crucial concern. Under this context, it is valuable to redesign the processes planning and its coordination through the use of Information & Communications Technology (ICT) and IoT that unifies the systems. Based on previous research, the general purpose is to generate a system model to examine healthcare quality of service and corroborate its effectiveness in a real environment. The aim of this paper focus on the development of a decision support model to define key areas where the inclusion of IoT would sustain the efficiency in health care service. The research methodology is based on case study, integrating planning processes, data analysis, scoring method that interacts with multicriteria approach. A pilot case study is pursued in health institutions in Chile, determining critical factors and the current automation level system appraisal to generate actions of improvement in processes that show poor service quality. The results give rise to the development of an investment plan that can be converted into action plans for a health institution.
VIRTUOSIDAD EN ORGANIZACIONES ESCOLARES ASOCIADA AL LIDERAZGO AUTÉNTICO DE SUS AUTORIDADES
Authors: Fernando Fernando , Perugini María Laura Lupano
Published: June 2020

El presente estudio se realizó en el marco de un ejercicio de reflexión sobre los elementos que contribuyen a fortalecer la calidad de la educación en Ecuador, desde el accionar de autoridades, docentes y estudiantes; su marco teórico de análisis fue la Psicología Positiva aplicada a la escuela como organización virtuosa. El objetivo fue identificar perfiles de organizaciones escolares percibidas como virtuosas, asociados a los niveles de liderazgo auténtico presentes en sus autoridades. Se trabajó con una muestra no probabilística de 209 autoridades educativas mediante la aplicación de las escalas de virtuosidad percibida en organizaciones escolares y liderazgo auténtico, en autoridades adaptadas a los contextos ecuatorianos. En primer lugar, se estableció la correlación presente entre las dimensiones de la virtuosidad percibida en organizaciones escolares y las dimensiones de liderazgo auténtico en autoridades; seguidamente, mediante las técnicas de conglomerados de k medias y  de análisis de varianza univariado (ANOVA), se identificaron dos niveles de liderazgo auténtico y dos perfiles de organizaciones escolares virtuosas relacionados con esos niveles de liderazgo, estos son: 1) organizaciones escolares virtuosas con liderazgos auténticos fortalecidos en sus autoridades; y, 2) organizaciones escolares en camino a la virtuosidad, con liderazgos auténticos en construcción en sus autoridades.
DESAFIOS DO ESTADO BRASILEIRO FRENTE À PANDEMIA PELA COVID-19: O CASO DA PARADIPLOMACIA MARANHENSE
Authors: Alvarenga Alexandre Andrade , Rocha Erika Maria Sampaio , Filippon Jonathan , Andrade Maria Angelica Carvalho
Published: June 2020

À medida que a atual pandemia se espalha pelo mundo, a ‘operação de guerra’ montada pelo governo maranhense para a compra de respiradores por meio de uma rota ‘alternativa’ apresenta-se como o disparador deste ensaio. A questão que nos move é entender por que um ente subnacional empenha esforços na busca da sua inserção internacional. Embora as evidências a respeito dos desafios brasileiros para lidar com o novo coronavírus no campo da Saúde Global sejam ainda incipientes, a partir da atuação internacional do Governo do Maranhão, notícias divulgadas na mídia e relatórios de organizações internacionais apontam para três elementos considerados fundamentais para esta análise: o discurso negacionista da Presidência da República do Brasil, que vem boicotando o enfrentamento da pandemia a despeito das evidências científicas; as tensões e os retrocessos diplomáticos com o maior parceiro comercial de medicamentos, equipamentos e materiais médico-hospitalares do Brasil; e os entraves nas relações entre o Brasil e os organismos internacionais de Governança Global da Saúde.
A Phase II Single Arm Pilot Study of the CHK1 Inhibitor Prexasertib (LY2606368) in BRCA Wild-Type, Advanced Triple-Negative Breast Cancer
Authors: Gatti-Mays Margaret E. , Karzai Fatima H. , Soltani Sanaz N. , Zimmer Alexandra , Green Jeffrey E. , Lee Min-Jung , Trepel Jane B. , Yuno Akira , Lipkowitz Stanley , Nair Jayakumar , McCoy Ann , Lee Jung-Min
Published: June 2020

Lessons Learned

Monotherapy with prexasertib demonstrated modest activity in BRCA wild-type, recurrent triple-negative breast cancer, highlighting the unmet need for combination treatment strategies. Neutropenia, anemia, and thrombocytopenia are common with the use of prexasertib but are manageable with supportive care measures. Prophylactic use of granulocyte colony stimulating factor should be considered to avoid dose reductions or treatment delays. Pharmacodynamic studies showed prexasertib treatment induced DNA damage in peripheral immune cells.

Background

Cell cycle checkpoint kinase 1 (CHK1) is a major G2/M cell cycle regulator in tumors with p53 dysfunction, such as triple-negative breast cancer (TNBC). We hypothesized the second-generation CHK1 inhibitor, prexasertib, would yield clinical activity in sporadic TNBC.

Methods

This single arm, phase II trial evaluated prexasertib at 105 mg/m2 IV every 2 weeks in patients with metastatic/recurrent TNBC. The primary endpoint was overall response rate (ORR).

Results

All nine patients enrolled were germline BRCA wild-type (BRCAwt) and had at least one prior treatment. One partial response (PR) was observed (ORR of 11.1%). Four patients experienced stable disease. The median progression-free survival (PFS) was 86 days (range 17 to 159 days). Grade 3/4 treatment-related adverse events included afebrile neutropenia (n = 8; 88.9%), anemia (n = 3; 33.3%), and thrombocytopenia (n = 1; 11.1%). Pharmacodynamic studies showed prexasertib treatment induced DNA damage in peripheral immune cells and demonstrated a decrease in activated/reinvigorated CD8 T cells; however, the one patient with a PR showed evidence of T-cell recovery.

Conclusion

Prexasertib monotherapy had modest clinical efficacy in BRCAwt TNBC. Further studies of prexasertib in combination with other agents are needed.
Yenidoğan Yoğun Bakım Ünitesinde Akut Periton Diyalizi Kullanımı ve Sonuçları
Authors: EMİROĞLU Nuriye , ALTUNHAN Hüseyin
Published: June 2020

Öz: Amaç: Akut periton diyalizi (APD) yapılan yenidoğanların altta yatan nedenlerini ve sonuçlarını değerlendirmekGereç ve Yöntem: APD yapılan hastaların çoğunda akut böbrek
yetmezliği (ABY)  (n=21, %70) ve
sepsis-dirençli metabolik asidoz (n=5, %16.7) vardı. ABY'nin diğer nedenleri renal
agenezi (n=2, %9.5), perinatal asfiksi (n=4,%19),
multikistik displastik böbrek (n=3, %13.3)
ve konjenital kalp hastalığı (n=4, %19) idi.
Ortalama diyaliz süresi 7.8±9.3 gün idi. En sık görülen komplikasyonlar kateter
tıkanıklığı (n=8, %34.8) ve kateter girişinden sızıntı (n=5, %21.7) idi.
Mortalite oranı % 70 idi; 8 hasta (%38) APD sürecinde altta yatan hastalıklar
nedeniyle öldü. Hayatta kalan 9 hastanın izlemi sırasında 3 hasta (%33.3) tam
remisyon gösterdi, ancak kalan 6 hastada kronik böbrek yetmezliği, altta yatan
metabolik hastalıklarına yönelik klinik bulgular devam etti.Bulgular: APD yapılan hastaların çoğunda akut böbrek
yetmezliği (ABY)  (n=21, %70) ve
sepsis-dirençli metabolik asidoz (n=5, %16.7) vardı. ABY'nin diğer nedenleri renal
agenezi (n=2, %9.5), perinatal asfiksi (n=4,%19),
multikistik displastik böbrek (n=3, %13.3)
ve konjenital kalp hastalığı (n=4, %19) idi.
Ortalama diyaliz süresi 7.8±9.3 gün idi. En sık görülen komplikasyonlar kateter
tıkanıklığı (n=8, %34.8) ve kateter girişinden sızıntı (n=5, %21.7) idi.
Mortalite oranı % 70 idi; 8 hasta (%38) APD sürecinde altta yatan hastalıklar
nedeniyle öldü. Hayatta kalan 9 hastanın izlemi sırasında 3 hasta (%33.3) tam
remisyon gösterdi, ancak kalan 6 hastada kronik böbrek yetmezliği, altta yatan
metabolik hastalıklarına yönelik klinik bulgular devam etti.Tartışma: APD
yenidoğan yoğun bakım ünitelerinde sıklıkla kullanılan tedavi şeklidir.
Peritonit gibi hayatı tehdit eden komplikasyonları olsa da, bu tür
komplikasyonlar nispeten daha az yaygındır. APD ihtiyacı için erken tanıma ve
erken APD işleminin başlaması bu hastalarda mortalitenin azalmasına katkıda
bulunabilir.
Evaluation of the prevalence and distribution of congenital heart diseases who presented to a pediatric cardiology outpatient clinic
Authors: ÇAĞLAR Hanife Tuğçe , SERT Ahmet
Published: June 2020

Introduction: The present study aimed to determine the prevalence and distribution of congenital heart disease in patients who presented to the paediatric cardiology outpatient clinic in Turkey.
Methods: File records of the children who underwent transthoracic echocardiography within the 3-year period between January 2013 and December 2015 at the paediatric cardiology outpatient clinic were retrospectively evaluated. Congenital heart diseases were grouped as follows: diseases with a left-to-right shunt, obstructive diseases, cyanotic diseases, cardiac malposition, vascular ring and unclassified diseases. Prevalence of the diseases, distribution among gender and age groups were investigated.
Results: This study included 12,342 subjects; 6996 (56.7%) subjects were male and 5346 (43.3%) subjects were female. The subjects were aged between 1 day and 18 years, and the mean age was 6.86 ± 5.39 years; 27.7% of the subjects were determined to have congenital heart disease. The prevalence of congenital heart disease was higher in males and in the 0–1 month age group. Of the subjects with congenital heart disease, 87% had a disease with a left-to-right shunt, 21.2% had an unclassified disease, 7% had obstructive disease, 1.6% had cyanotic disease, 0.8% had a vascular ring and 0.7% had cardiac malposition.
Conclusion: We recommend performing echocardiography on patients presenting to a paediatric cardiology outpatient clinic. Conducting echocardiographic examination on new-borns who are referred to the paediatric cardiology department within the first month of life would enable detecting, particularly the diseases with a left-to-right shunt and cyanotic congenital heart diseases, and ensure timely treatment planning.
The use of bone grafts in dental practice
Authors: Melo de Matos Jefferson David , Santos Diamantino Pedro Jacy , Sussumu Nishioka Renato , Bottino Marco Antonio , Da Rocha Scalzer Lopes Guilherme , Cabral Andrade Valdir
Published: June 2020

Introduction: The aim of this study is to describe, via literature review, the use of bone grafts and the types most commonly used to rebuild following alveolar bone loss.

Methodology: This literature review was conducted using the following databases: Pubmed (https://www.ncbi.nlm.nih.gov/pubmed), Scielo (http://www.scielo.org/php/index.php). The keywords for the textual search were: Bone Regeneration; Alveolar Bone Grafting; Dental Research; Dentistry. The inclusion criteria were: Literature that covers the subject under study, Literature of the last five years (from 2014 until 2019), English Language, systematic review, laboratory and clinical studies. The exclusion criteria were: literature review, letter to the editor, opinion article, literature duplicated in databases and literature that did not address the variables under study.

Literature Review: 186 articles were found, but according to the inclusion criteria, only 30 were selected for this study. Bone is a specialized, vascularized and dynamic connective tissue that changes over the life of the organism. When injured, it has a unique capacity for regeneration and repair without the presence of scars, but in some situations due to the defect size, the bone tissue does not regenerate completely; thus, it is necessary to perform bone grafting procedures.

Conclusion: The use of bone grafts in dentistry is shown to be a very effective and useful resource considering its great applicability in bone reconstructions in various areas of dentistry. However, greater knowledge about the viability and

influence of biomaterials, whether associated to autogenous grafts or not, on bone repair is necessary.
Medidas de mitigación y corrección que utiliza el Estado para subsanar los daños producidos por los entables mineros en el barrio El Oasis del municipio de Certegui, departamento de Chocó
Authors: Palacios Mena Denier , Moreno Rodallega Maryuri
Published: June 2020

Objeto: la investigación está orientada a determinar las medidas de mitigación y corrección que utiliza el Estado para subsanar los daños producidos por los entables mineros en el barrio El Oasis del municipio de Certegui, departamento de Chocó, teniendo en cuenta lo normado en la Ley 99 de 1993 y la Ley 70 de 1993 (Ley de las Comunidades Negras), en su artículo 29.  

Metodología: se hace un análisis prospectivo que permite conocer detalladamente qué efectos presenta la actividad minera en el barrio El Oasis. Las leyes que hacen parte de esta investigación son tenidas en cuenta para esclarecer el cumplimiento por parte del Estado en las zonas apartadas del gobierno central e igualmente el diseño institucional del municipio de Certegui.  

Hallazgos: a nivel nacional, se presentan serias deficiencias para afrontar los problemas ambientales, materializados en la adopción de personal más idóneo, debido a que las universidades apenas están empezando a formar en especializaciones y pregrados como Derecho Agrario o Derecho de Suelos, y la educación ambiental está en pleno reconocimiento académico que gestione y promueva políticas públicas basadas en la sostenibilidad del suelo. A su vez, faltan entes que vigilen de manera rigurosa cada uno de los daños producidos por entables mineros y que de manera directa degradan el suelo. 

Conclusiones: a la fecha, se desconoce el motivo por el cual la Corte Constitucional no manifestó el soporte normativo del concepto de derechos bioculturales. Es importante recalcar que, en el derecho interno, sí existe este antecedente, evento de suma importancia para la revolución ecológica, que empieza a ver en ello el fruto de su arduo trabajo.
Análisis de la evolución legal del ejercicio médico en Colombia
Authors: Galán Camargo Viviana
Published: June 2020

Objetivo: la presente investigación tiene la finalidad de ilustrar al lector sobre la problemática de la impunidad en Colombia, enfocada en los casos de responsabilidad médica por fallas en la prestación del servicio de salud, mediante un estudio que reunirá aspectos sociológicos, jurídicos y estadísticos, al paso que será relevante discutir la evolución jurisprudencial en el campo de la salud como derecho fundamental y como servicio a cargo del Estado. 

Metodología: se analizará la “lex artis” desde el aspecto científico del derecho y algunos puntos de vista con tendencia científica, filosófica de técnica y arte, a la vez aplicados en contraposición a la actividad jurídica, a fin de entender en alguna medida el ejercicio jurídico respecto a la actividad médica, dentro del marco referencial legal establecido para el comportamiento ético del profesional sanitario.  

Hallazgos: mediante el análisis de los conceptos de injerencia o criterios a tener en cuenta en la apreciación jurídica del caso médico, se estudiará tal procedimiento, con lo que se busca organizar y entender la estructura de la actividad jurídica en el caso concreto.  

Conclusiones: la relación médico-paciente y los problemas jurídicos que entre estos se suscitan son consecuencia de la ausencia de una regulación jurídica clara y concreta de las acciones que de la práctica médica se derivan, en la que esta es solo una parte de la entramada actividad pecuniaria del sector salud.
Tendencia actual de la responsabilidad estatal en procesos de privación injusta de la libertad proferidos por la Sección Tercera del Consejo de Estado en los años 2016 a 2017
Authors: Ramírez Rivas Andrea Del Pilar
Published: June 2020

Objeto: en Colombia se observa el problema reiterado de las detenciones masivas; y se han vuelto cada vez más frecuentes las prácticas arbitrarias y la utilización inadecuada del poder al privar a un ciudadano de la libertad. El Estado social de derecho está fundado en la dignidad de la persona humana, por lo que no puede estructurarse ni funcionar con base en el desconocimiento de los derechos de los particulares.  

Metodología: definir las líneas jurisprudenciales y el alcance de la responsabilidad patrimonial en las acciones de reparación directa en procesos de privación injusta de la libertad en la Sección Tercera del Consejo de Estado adquiere importancia desde el punto de vista de las ciencias jurídicas, por cuanto se requiere tener una claridad conceptual sobre el actual reconocimiento de los perjuicios extrapatrimoniales en Colombia.  

Hallazgos: esto le está ocasionando problemas al Estado, entre ellos las demandas por responsabilidad estatal, generando un detrimento patrimonial.  

Conclusiones: la sujeción de los procedimientos legales a los principios fundamentales del derecho son la vía más segura para evitar fallas o vulneraciones de derechos que a posteriori generen la obligación estatal de asumir responsabilidades y reparar daños por vías de indemnización de perjuicios, bien sean estos patrimoniales o extrapatrimoniales.
Transición a la maternidad/ paternidad y prácticas de crianza en tres generaciones
Authors: Robles-Estrada Erika , Oudhof-van Barneveld Hans , Mercado-Maya Aída
Published: June 2020

Objetivo: se analizó la transición a la maternidad/paternidad y la percepción de las prácticas de crianza en tres generaciones de 18 hombres y mujeres de la ciudad de Toluca, México.

Metodología: se empleó la entrevista a profundidad y para el análisis de la información, el método fenomenológico.

Resultados: la transición a la maternidad/paternidad mantuvo elementos constantes entre generaciones, así como en la práctica de crianza del fomento de las buenas relaciones entre hermanos. Los aspectos dinámicos estuvieron en el cuidado de la salud física y mental, control coercitivo y apoyo escolar. La práctica constante en las dos primeras generaciones y dinámica en la tercera fue, enseñar el papel de niña o niño.Conclusiones: se concluye que la transición a la maternidad/paternidad es un proceso interno, mientras que las prácticas de crianza dependen del contexto sociocultural.
Rethinking repetition in dementia through a cartographic ethnography of subjectivity
Authors: Jeong Jong-min
Published: June 2020

This article critically engages with the predominant understandings of repetitive bodily practices within a dementia context. Rather than interpreting such practices as pathological and abnormal, I instead approach them through an ethnographic mapping, paying particular attention to the affective dynamics of repetition. Critically developing Fernand Deligny’s insights and methods of tracing and mapping bodily movements in dialogue with Tim Ingold’s notion of dwelling, I demonstrate affect-underpinned encounters and interactions of repetitive phenomena. I then argue for the extension of recent anthropological discussions about affect, repetition, and subjectivity by suggesting a more productive dialogue among theories of affect, body, atmosphere, cognition, memory, language, and life history.
Autism as heredity, autism as heritage
Authors: Belek Ben
Published: June 2020

Kinship relations constitute the grooves through which autism travels temporally. On the one hand, the biological components of the condition are understood to journey from one generation to the next through the passing down of genetic information. Yet on the other hand, autism is often employed retrospectively as an explanatory model and a marker for a unique personhood; this can occur in retelling to oneself and to others the story of one’s familial history, as well as, sometimes, the story of humanity as a whole. In this way, autistic people’s construction of autism as a cross-generational familial keystone offers them new opportunities for self-expression and self-creation. Through this temporal reframing of autism, the hereditability of the condition might instead be reconceptualised as heritage.
Making bodies kosher
Authors: Qureshi Kaveri
Published: June 2020

n/a
Urinary Incontinence Data v1
Authors: Jaffar AIda
Published: June 2020

Background Urinary Incontinence (UI) is when a person is unable to hold his/her urine effectively. This is a common problem which can develop and worsen during pregnancy. An effective way to manage UI is to educate patients on the Pelvic Floor Muscle Exercise (PFME) regularly. The present study aimed to ascertain the pregnant women’s knowledge, attitudes, and practices (KAP) related to PFME. Methods This was a cross-sectional study done in a one primary care clinic located in a semi-urban area in Selangor, Malaysia. Simple random sampling was conducted among pregnant women aged 18 years old and above at any gestation. The validated study instruments used consisted of questions on socio-demography, KAP on UI,and also the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form to determine UI among the respondents. Results The response rate for this study was 72.1%, where 440 pregnant women consented to take part in the study. The median age of study respondents was 30 years old and majority of the study respondents was from the Malay ethnicity (80.9%). The prevalence of UI was 40.9%. The proportion of pregnant women with good knowledge, attitude and practice scores were 58.0%, 46.6% and 45.2% respectively. There was a significant association between UI and age (p=.03), body mass index (p=.03), ethnicity (p=.04), gravida. (p=.001), knowledge on PFME (p=.007) and attitude towards PFME (p=.006). Conclusions Findings from this study fill a gap in the prevalence and KAP concerning PFME at the primary care level. The foundation areas for future education and health promotion on UI should address the importance of correct PFME. This education can be delivered through a pragmatic way to ensure its effectiveness and sustainability of the health promotion program.
Perceptions, knowledge and attitudes of the adult populations towards COVID-19 : A scoping review protocol v1
Authors: Clavel Nathalie , Seppey Mathieu , Gautier Lara , Lavoie-Tremblay Mélanie
Published: June 2020

Perceptions, knowledge and attitudes of the adult populations towards COVID-19 are key factors in the community transmission of SARS-CoV-2. During outbreaks, populations play a key role in limiting the spread of infectious diseases by adopting preventive measures. In the context of COVID-19 pandemic, identifying the perceptions, knowledge and attitudes of the populations is important to implement appropriate and effective preventive measures that will help to control and stop the spread of COVID-19. This scoping review aims to understand the perceptions, knowledge and attitudes of the adult populations towards COVID-19. We will conduct a comprehensive search of the following electronic databases: MEDLINE-Ovid, EMBASE-Ovid, PsycINFO-Ovid, Web of Science, and CINAHL (EBSCO). The searches will be conducted in English. All study designs will be included in the searches, both qualitative and quantitative. A comprehensive search of the grey literature, including preprints, will also be undertaken through Google Scholar, Semantic Scholar, CADTH Covid-19, Faculty Opinions, Publons and Medrxiv. We will also search the World Health Organization, Centers for Disease Control and Prevention, Center for Infectious Disease Research and Policy websites and any other relevant COVID-19 related websites.
MENGEMBANGKAN SIKAP DAN PERILAKU ANAK USIA DINI MELALUI PENDIDIKAN BERBASIS KARAKTER
Authors: Rohendi Edi
Published: June 2020

Pendidikan karakter merupakan upaya-upaya yang dirancang dan dilaksanakan secara sistematis untuk membantu peserta didik memahami nilai-nilai perilaku manusia yang berhubungan dengan Tuhan Yang Maha Esa, diri sendiri, sesama manusia, lingkungan. Kemudian nilai-nilai tersebut dapat terwujud dalam pikiran, sikap, perasaan, perkataan dan perbuatan. Sesuai dengan karakteristikanak usia dini, maka sifat-sifat materi pembelajaran  adalah materi yang bersifat aplikatif, enjoyble, dan mudah ditiru.Dalam pengembangan sikap dan perilaku anak usia dini berbasis karakter, terdapat empat hal penting yang mesti diperhatikan ketika mereaktualisasikan pendidikan karakter, yakni melalui: (1) memberi pemahaman yang benar tentang pendidikan karakter, (2) pembiasaan, (3) contoh atau teladan, (4) pendidikan atau pembelajaran secara integral.
URGENSI PERMAINAN TRADISIONAL DALAM MENGEMBANGKAN KECERDASAN SOSIAL ANAK USIA DINI
Authors: Meha Nehru
Published: June 2020

Playing is very familiar with the activities of human life. At times people are in the phase of growth and development from childhood to adulthood almost none of individual who do not know "game”. Based on the scientists’ study in the field of psychology, education, social, and humanities, show that game greatly affects the child's development. In the current era of globalization, many traditional games have been abandoned because they affected the various types of modern games. Even if the traditional games are still standing, it is only certain types and in certain places as well. Very relevant when traditional games children were exhumed in connection with the growing dominance of the modern game in the lives of children, as well as an effort to keep the traditional game is not extinct. Traditional games to develop various aspects of intelligence and potential of children and inculcate positive values. Organization of early childhood education requires the right approach to optimize the potential of intelligence of children, including through local cultural approach which is a traditional play.Keywords: Social Intelligence, Early Childhood and Traditional Play
STANDART PENETRASYON TESTİ (SPT) ile AFYONKARAHİSAR MERKEZ UYDUKENT BÖLGESİ ZEMİNLERİNİN SIVILAŞMA POTANSİYELİNİN ARAŞTIRILMASI
Authors: ZORLUER İsmail , GÜCEK Süleyman
Published: June 2020

Bu çalışma, Afyonkarahisar il merkezinde 9 mahalleyi kapsayan Uydukent bölgesinin olası bir deprem etkisinde, yerleşim alanı içerisindeki alüvyal zeminlerin sıvılaşma potansiyelinin, arazi (SPT) verileri kullanılarak belirlenmesini içermektedir. Bu amaçla 70 noktada yapılan SPT verileri kullanılmıştır.
Akşehir-Gediz Fay Sistemi, bölgeyi etkileyebileceği ve en büyük ivmeyi yaratabileceği varsayılarak araştırmaya esas alınmıştır. Güncellenen 2019 deprem haritası üzerinden 0,4g büyüklüğünde yatay deprem ivmesi oluşabileceği hesaplanmış, Mw=5.0, 6.0, 7.0 olan senaryo deprem büyüklüklerinde SPT verileri kullanılarak sıvılaşma analizleri yapılmıştır. Analiz sonuçlarına göre çalışma sahasını temsilen, bölge genelinde orta ve yüksek dereceli sıvılaşma riski olasılıkları belirlenmiş ve buna göre sıvılaşma risk haritası ortaya konulmuştur.
A RESEARCH ON THE EFFECTS OF PESTICIDES AND WOOD VINEGAR ON WEEDS AND CULTIVATED PLANTS IN WHEAT AGRO-ECOSYSTEM
Authors: KOÇ İbrahim , YILDIZ Şenol , YARDIM Erdal Necip
Published: June 2020

This study was carried out to determine the effects of pesticides and wood vinegar that are used for the plant protection in wheat agro-ecosystems on weeds and cultivated plants in 2014-2015 and 2015-2016 production seasons in Muş Province ecological conditions. The field experiment was done in wheat field according to randomized block design with four repetition. Treatments in the experiment was based on the pesticides used by BERCE Alparslan agricultural enterprise and treatment schedule of the company. These treatments were: 1) Pesticide treatment (fungicide, herbicide), 2) 0.5% - 1% - 2% - 3% - 4% and 5% ml wood vinegar treatments that correspond to pesticide treatment, 3) Control treatment with tap water. It was observed that when compared to control group, pesticide treatment decreased weeds the number of, variety and the dry weight (P=0.002), however, it significantly increased values such as grain size, number of seed per spica, grain yield per spica and harvest index (%) of cultivated plants (P≤0.05). On the other hand, use of 1% ml wood vinegar had a significant effect on higher yield index (P≤0.05).
GÖRÜNTÜ İŞLEME YÖNTEMİ İLE BETONARME KİRİŞ DEPLASMANLARININ BELİRLENMESİ
Authors: KAÇIN Selçuk , AYDIN Mesut
Published: June 2020

Bu çalışmada 150x230x1400 mm boyutlarındaki, eğilme deneyine tabi tutulan betonarme kirişlerin davranışı görüntü işleme metodu kullanılarak tespit edilmeye çalışılmıştır. Kirişlerde yükleme sonucu oluşan çatlakların tespit edilmesi, kiriş yüzey gerilmelerinin zamana bağlı değişiminin görselleştirilmesi ve kirişlerin yüzeyinde oluşacak olası çatlakların çatlama olmadan önce belirlenmesi amacı ile görüntü işleme tekniği kullanılmaktadır. Kirişlerdeki zamana bağlı oluşan deplasmanların görüntü işleme tekniği ile belirlenerek, klasik yöntem olan deney düzeneğinden deplasman ölçerle elde edilen deplasman değerleri ile karşılaştırılması amaçlanmaktadır. Bu amaçla kirişler eğilme düzeneğine alınmadan önce birtakım boyama işlemlerine tabi tutulmuş daha sonra yüksek çözünürlüklü kamera ile video kayıtları alınmıştır. Elde edilen görüntüler görüntü işleme paket programları ile analiz edilerek deplasman değerleri, çatlaklar ve gerilme dağılımı belirlenmeye çalışılmıştır. Bu deney özelinde görüntü işleme tekniğinin inşaat mühendisliği laboratuar uygulamalarında kullanımının avantajları tartışılacaktır.