bluuebunny/crossref_metadata_2025 huggingface dataset:
Hybrid Control using Adaptive Particle Swarm Optimization and Integral Backstepping Control of Grid-connected Doubly Fed Induction Generator
Authors: Chetouani Elmostafa , Errami Youssef , Obbadi Abdellatif , Sahnoun Smail
Published: November 2021

We proposed an analysis of a hybrid control of active and reactive power for a doubly-fed induction generator for variable velocity wind energy injection into the electrical grid using a combination of adaptive particle swarm optimization and integral backstepping control in this paper. The stability of the Lyapunov function is utilized to establish the latter. Six controllers are developed as part of the proposed control process: The first is concerned with the maximum PowerPoint. The stator powers are managed by the second and third regulators, which are performed by the optimal PI controller using adaptive particle swarm optimization. The DC link voltage is kept constant by the fourth controller. The fifth and sixth are employed to pilot the rotor powers and ensure that the power factor is maintained to 1. These three controllers are synthesized by using the nonlinear integral backstepping control. These control strategies show excellent results compared to field-oriented control under a variable wind speed profile and changing generator settings in a Matlab/Simulink environment. According to the test findings, using integral backstepping, the overshoot of the DC-link voltage is decreased by 99.16 %. Furthermore, the particle swarm optimization reduces its time to reach the equilibrium state to 4.3 m s and demonstrates robustness against parameter generator changes.

HIGHLIGHTS

The regulation of the produced power by the wind energy conversion system (WECS) based on a doubly-fed induction generator is becoming increasingly important to researchers. This system is modeled and simulated in the Matlab/Simulink software environment to apply the proposed control

In order to extract the maximum power from the variable wind source, a maximum power point tracking method is developed based on the PI controller

For piloting the wind energy system conversion (WECS) based on a DFIG, a combination of the integrated Backstepping controller and adaptive PSO is proposed and realized in this paper

Robustness tests are established by adjusting the generator parameters, and a comparative study is conducted to verify the superiority of the suggested control over the indirect vector control

GRAPHICAL ABSTRACT
Effect of Pursed-Lip Breathing using a Windmill Toy Model on Breathing Efficiency in Chronic Obstructive Pulmonary Disease Patients
Authors: Jansang Sarawut , Tungsukruthai Parunkul , Srisuma Sorachai , Sriyakul Kusuma , Krajarng Aungkana , Kietinun Somboon
Published: November 2021

Chronic obstructive pulmonary disease (COPD) is the third-highest cause of death in the world, also true in Thailand. There are various methods to treat COPD such as medication and non-drug therapies for respiratory rehabilitation. The aim of this study is to investigate the effectiveness of pursed-lip breathing (PLB) by using a windmill toy in COPD patients. The participants in this randomized controlled trial study were 60 to 75 years old. The total number of 46 participants were equally divided into 2 groups: The intervention group and the control group (23 participants each). The intervention group used breathing training through a windmill toy, whereas the control group received training in standard breathing patterns. The training was performed over sessions in 1 week. Lung function, respiratory muscle strength, and 6-minute walk test (6MWT) were recorded at baseline, and between 6 - 12 weeks (follow-up). The intervention group and the control group improved significantly in lung function and muscle strength (p < 0.05). In addition, 6MWT in the intervention group increased significantly when compared to the control group (p < 0.05) at week 12. In conclusion, the PLB using a windmill toy is a new form of breathing training that is effective in promoting the strength of the muscles used for breathing, lung performance, and cardiovascular function in COPD patients.

HIGHLIGHTS

The use of windmill toys is a new form of breathing exercise that is effective in strengthening

Using innovative models applied in medicine and public health to promote prevention of severe disease

The greatest benefit of pulmonary function training is that patients have a better quality of life and longer life
Virtual Reality for Modern Society
Authors: H R Mr. Manjunath , Moolya Shreyas , Ahamed Fayiz , Shreya  , Prathiksha
Published: November 2021

Treatment and recovery of the intellectual, mental, and engine sequela of focal sensory system brokenness regularly depends on appraisal instruments to illuminate conclusion and to follow changes in clinical status. Regularly, these evaluations utilize paper-and-pencil psychometrics, involved simple/PC tests, and rating of conduct inside the setting of true useful conditions. The current survey talks about the utilization of virtual reality (VR) innovation in clinical medication, particularly in careful preparing, torment the board and restorative treatment of psychological maladjustment. We present the regular kinds of VR test systems and their operational standards in previously mentioned fields. The clinical impacts are additionally talked about. In pretty much every examination that managed VR test systems, scientists have come to a similar end result that the two specialists and patients could profit by this novel innovation. In addition, favourable circumstances and burdens of the use of VR innovation in each field were talked about, and the future exploration headings were proposed
Mixed Aqueous Surfactants Solution for Rapid Oil Extraction from Palm Kernel Seed
Authors: Makun Baba , Salam Kamoru Adio , Evuti Abdullahi Mohammed , Adepoju Tunde. F.
Published: November 2021

Adverse effects associated with the use of hexane or other similar organic extraction solvents for extracting oil from oilseeds have been a drive for alternative less toxic oil extracting solvents. This research focuses on oil extraction from grinded palm kernel using solution of mixed aqueous polyoxythylene (23) lauryl ether (BRIJ-35) and sodium dodecyl sulphate (SDS) surfactants and sodium chloride (NaCl) as the electrolyte. Grinded Biomass was agitated in the solution of the mixed surfactant, allowing the extracted oil to be liberated from the seeds as separate phase from the aqueous phase. The effect of SDS concentration, NaCl concentration, contact time and liquid/seed ratio on oil yield was studied. The extracted oil was subjected to Fourier Transform Infrared Spectroscope (FT-IR) characterization to determine the functional groups present in the oil. At optimum conditions for the mixed aqueous surfactant extraction (0.2379 wt.% SDS, 0.5995 wt.% BRIJ-35, 0.3wt.% NaCl, 10 ml/g liquid/solid ratio, 25 min contact time at 25oC), an optimum 78% oil yield was obtained. In contrast, at 50oC for 24hr, an optimum of 81% and 82% oil yield were obtained respectively when hexane and petroleum ether were used as oil extracting solvents. Addition of BRIJ-35 and NaCl to the SDS solution improved the oil yield. Oil extracted using mixed aqueous surfactants, petroleum ether and hexane have the same functional groups indicating the surfactant does not affect the quality of the oil extracted.
Antiplasmodial Activities of Some Locally Prepared Herbs Against Plasmodium falciparum Obtained from Asymptomatic School Children in Zaria, Kaduna State, Nigeria
Authors: D Balogun Islamiat , I Inabo Helen , E Ella Elijah
Published: November 2021

The efficacy of current or any intended antimalarial can only be resolute by cultivation and susceptibility studies. The aim of this research was to cultivate Plasmodium falciparum in vitro and comparing the antiplasmodial effects of standard antimalarial medications including herbaceous preparation. Asymptomatic pupils attending some schools in Zaria, Kaduna state, Nigeria were recruited into this research and blood samples were collected from them. Microscopy was done after thin and thick blood films were prepared and stained. The antiplasmodial activities of antimalarial drugs as well as herbal preparation were determined after the successful culturing of red blood cells in the Jatropha curcas medium.The phytochemical constituents of the herbs that made up the concoction were determined. The incidence of asymptomatic Plasmodium infection amongst school kids was 17.5%. There was no statistical association of location, gender and age with the obtained prevalence. Presence of alkaloids was observed in every plant screened while the same was also observed for tannins except in Enantia chloranta.Steroids and phlobatanins were observed in Citrus aurantifolia while there was presence of saponins in all the plant extracts except Cymbopogbon citratus. All the plants except Enantia chloranta contained flavonoids. There was presence of terpenoids in all screened plants except Azadirachta indica and Cymbopogbon citratus while cardiac glycosides were found in every plant except Magnifera indica and Enantia chloranta. Results obtained from the in vitro cultivation of the Plasmodium falciparum with Athemether/lumefanthrine, amodiaquine and herbal concoction showed average percentage parasite inhibition of 80%, 37.8% and 38.6% respectively. This implies that Arthemether/lumefanthrine was capable of inhibiting the growth of the parasite best. The herbal concoction also inhibited growth (38.6% inhibition). There is need for additional investigation on a wider variety of plants to explore their antiplasmodial activities since there is evidence that it works, and it is quite available and affordable.
Crude Ethanolic Stem Bark Extract of Zanthoxylum zanthoxyloides and Its Fractions: In-Vitro and In-Vivo Antiplasmodial Activity
Authors: Rukayyah Sulaiman S. , Ali Jigam, Audu , Abdulkadir Abubakar , Bolakale Salau, Rasaq
Published: November 2021

Malaria is a global problem, as treatment failure has hampered the efficacy of most anti-malarial medications. The goal of this study was to see if stem bark extract from Zanthoxylum zanthoxyloides had antiplasmodial properties that could be used to treat both susceptible and resistant parasites. The stem bark of Z. zanthoxyloides (500g) was crushed and extracted with ethanol. The extract was tested for antiplasmodial activity in vitro against the chloroquine-sensitive (CQS) strain NF54 and chloroquine-resistant strains (CQR) K1 of P. falciparum, as well as in vivo against the CQS(NK65) strain of P. berghei at 100, 200, and 400 mg/kg bw. Bioassay-guided fractionation of the extract was performed. The crude extract had an in vitro activity of 1076.4 56.4 and 1315.1 121.6 ng/ml against chloroquine sensitive and resistant parasites, respectively while standard drugs (chloroquine and artesunate) were 10.94 nM (3478.92 ng/ml) and 9.24 nM (3215.52ng/ml) for CQS and 310.68 nM (98796 ng/ml) and 10.94 nM (3650.52 ng/ml) for CQR respectively. At Day 7, mice treated with 100, 200, and 400 mg/kg bw crude extract had parasite densities of 1159, 928, and 869 parasites/ µl, respectively (compared to positive control that had 123 parasites /µl). In vitro antiplasmodial activity was best in the K2, K4, and K6 fractions (IC50 were 6670, 6890, and 6480 ng/ml), but in vivo antiplasmodial activity was best in the K4 fraction (1183 parasites/ µl).The stem bark extract of Z. zanthoxyloides have remarkable antiplasmodial activity against both chloroquine sensitive and drug resistant P. falciparum supporting it ethnomedicinal use in malaria treatment.The extract of Z. zanthoxyloides has promising antiplasmodial activity and could be used to generate therapeutic leads against the multidrug-resistant K1 strain of P. falciparum, in addition to providing an alternative allopathic antiplasmodial medication.
Hydrocarbon Degrading Potentials and Antibiotic Susceptibility Test of Bacteria Isolated from Amended Soil in Ilorin
Authors: D. O. Adetitun , M.B. Oguntoye
Published: November 2021

This study used bacteria from hydrocarbon-contaminated soil that had been treated. Organic amendments included cassava peels, plantain peels, eggshells, and poultry droppings, while inorganic amendments included NPK and Urea. In this study, three (3) bacteria were characterized and dealt with: Bacillus amyloliquefaciens, Bacillus proteolyticus, and Providencia rettgeri. To determine their biodegradative capabilities, these isolates were tested on a variety of hydrocarbons. In addition, the antibacterial activity of the bacteria was tested in vitro against extracts of Moringa oleifera, Vernonia amygdalina (Bitter leaf), Ocimum gratissimum (Scent lLeaf), and Telifairia occidentalis (Ugwu) at different concentrations (20%, 13%, 10%, 7%, and 3%). Using the maceration procedure, the plant materials were extracted with ethanol and methanol. The bacteria were resistant to the various concentrations of plant extracts, according to the results. The methanolic and ethanolic extracts of Vernonia amygdalina (bitter leaf) had the maximum inhibition zone, measuring 6.00 ± 0.00 mm. Furthermore, all isolates were resistant to crude oil, engine oil, heptane, and benzene in antimicrobial tests on hydrocarbons, with Bacillus amyloliquefaciens having the highest level of susceptibility (18 mm) to pyridine. However, the bacteria all demonstrated broad spectrum susceptibility to the commercial antibiotics used as a control, with the exception of Providencia rettgeri, which proved resistant (5 mm) to Ampiclox (APX), Zinnacef (Z) and Amoxacillin (AM).
Experimental Investigation on the effect of Chemical Pretreatments of Slow-Pyrolyzed Nigerian Jatropha curcas L. Biomass Residues on Pyrolytic oil
Authors: Lateef Fatai Abiola , Ogunsuyi Helen Olayinka
Published: November 2021

In Nigeria, assemblage and discarding of residues from energy crops are increasingly becoming laborious and costly and may pose serious environmental challenges if not correctly managed. The Energy Commission of Nigeria’s long term (2016-2030) plan on the nation’s energy requirements is entirely non-fossil. This is attributable to the global decline of fossil fuel sources, soaring prices, climate crisis and the need to utilize hitherto abundant biomass resources for energy and chemical feedstocks purposes in Nigeria. In this research, an experimental study on the bio-oil generated through slow pyrolysis of Jatropha curcas L. biomass residues – Jatropha curcas L. seed shell (JSS) and Jatropha curcas L. fruit hull (JFH) were realized in a fixed bed reactor at 450 ℃ in a batch-wise step, biomass sample (1.14 mm) particle size, designed by authors. The biomass samples were subjected to pretreatment with 4% sulphuric and sodium hydroxide solutions each respectively. The Chemical compositions and functional groups available in the bio-oil of both raw and pretreated biomasses obtained at 450 ℃ were investigated by Gas Chromatography-Mass Spectrometry (GC-MS) and Fourier Transform- Infrared (FT-IR) spectroscopy analysis respectively. Scanning Electron Microscopy (SEM) was used to look into the residual biomass surface morphology of pretreated and untreated Jatropha curcas L. waste of JSS and JFH. The results acquired disclosed that the bio-oil obtained from JSS and JFH might be a principal liquid fuel starting point and chemical feedstocks.
Knockdown of SNW1 ameliorates brain microvascular endothelial cells injury by inhibiting NLRP3 inflammasome activation
Authors: Tao Zhen , Guo Hongwei , Tang Jigang , Cheng Ming
Published: November 2021

Introduction

SNW domain containing 1 (SNW1), as a splicing factor to regulate the activity of transcription factors, has been reported to be involved in multiple disease processes, including neuroblastoma. Whereas, the latent function and concrete mechanism of SNW1 in brain microvascular endothelial cells (BMECs) have not been clarified.

Material and methods

BMECs were induced by oxidized low-density lipoprotein (ox-LDL), and high fat (HF)-fed rats were established. After SNW1 knockdown or NLR family pyrin domain containing 3 (NLRP3) overexpression, SNW1 and NLRP3 expressions were monitored via RT-qPCR, Western blot, or immunohistochemistry assays. Also, cell viability, apoptosis, and cholesterol efflux were determined via CCK-8, flow cytometry, and related kits; IL-18 and IL-3 levels were also certified by ELISA kits; and NLRP3 inflammasomes and cholesterol efflux-related proteins were identified by Western blot in vitro and in vivo.

Results

We discovered that ox-LDL or HF-feeding significantly elevated SNW1 and NLRP3 expressions, and prominently induced BMECs injury in BMECs or rat brain tissues. Subsequently, our data confirmed that SNW1 knockdown markedly accelerated cholesterol efflux and viability, and prevented apoptosis and NLRP3 inflammasomes, which also could be reversed by NLRP3 overexpression in ox-LDL-induced BMECs. In addition, we showed that SNW1 knockdown could signally induce cholesterol efflux and repress NLRP3 inflammasome activation in HF-fed rats.

Conclusions

We demonstrated that SNW1 knockdown has a great protection effect on the dysfunction of BMECs by inhibiting NLRP3. So, SNW1 might be a therapeutic target for BMECs injury.
Wogonoside: Anti-human colon cancer activities and survey of HMG-CoA ‎reductase inhibition properties with molecular modeling
Authors: Liu Jiamiao , Tan Huifang , Zeng Qing
Published: November 2021

Introduction

The biological activities and interactions of wogonoside in the presence of HMG-COA reductase were investigated using the molecular docking study as a versatile theoretical approach. Wogonoside showed a considerable binding affinity to the enzyme with a docking score of -7.582 kcal/mol.

Material and methods

The in vitro cytotoxic and anti- colon ‎ carcinoma effects of biologically synthesized Wogonoside ‎against GP5d, MDST8‎, HCA-46‎, HT115, LS174T, and COLO 320DM cancer cell lines were ‎assessed.

Results

The results indicated that the compound makes hydrophobic contacts with essential residues of the catalytic domain of the enzyme. Therefore, wogonosid could be considered as a potential inhibitor for HMG-COA reductase. The IC50 of the Wogonoside were 105, 198, 173, 382, 71, and 183 µg/mL against GP5d, ‎MDST8‎, HCA-46‎, HT115, LS174T, and COLO 320DM cancer cell lines. The anti-colon‎ ‎carcinoma properties of the Wogonoside could significantly remove GP5d, MDST8‎, HCA-46‎, ‎HT115, LS174T, and COLO 320DM cancer cell lines in a time and concentration-dependent ‎manner by MTT assay. ‎

Conclusions

It appears that the anti-human colorectal carcinoma effect of recent nanoparticles is due to their antioxidant effects. We have obtained results for the HMG-CoA Reductase enzyme at the micromolar level. In our study, inhibition result of on HMG-CoA reductase showed lower values 28.70±4.73 micromolar.
The distress and needs of Chinese patients with pituitary adenoma: a preliminary survey
Authors: Shen Meifen , Sheng Guixiao , Yang Yan , Wu Chao , Ma Chen , Yang Li , Huang Yulun
Published: November 2021

Introduction

It is necessary to investigate the current psychological distress and needs status of patients with pituitary adenoma in China.

Material and methods

Patients with pituitary adenoma treated in our hospital from May 2019 to December 2019 were included. The psychological distress and needs scale for pituitary adenoma patients was used to investigate the psychological distress and needs of patients. Besides, univariate and multiple linear regression analyses were conducted to analyze the influencing factors.

Results

A total of 254 valid questionnaires were included. The total psychological distress and need score of patients with pituitary adenoma was (23.89±18.41) and (21.91±20.03) points respectively. There were significant differences on the psychological distress score in different occupational status, personal income, types of pituitary adenomas, size of pituitary adenoma, invasiveness, endocrine level and history of surgery (all p<0.05). The size of pituitary adenoma, endocrine level and pituitary adenoma type were the influencing factors of patients' psychological distress(all p<0.05). There were significant differences on the need score in different age, occupational status, personal income, types of pituitary adenomas and endocrine level(all p<0.05). Endocrine level, other rare types of pituitary adenoma and age were the influencing factors of patients' needs (all p<0.05).

Conclusions

Our study is one of the few studies focused on the psychological distress and needs status of Chinese patients with pituitary adenoma. Medical staff should pay attention to the psychological distress of patients with large, rare type of pituitary adenomas and abnormal endocrine level, and take corresponding interventions to alleviate their psychological distress.
Effects and safety of intraoperative intermittent pneumatic compression for preventing postoperative venous thromboembolism: a meta-analysis
Authors: Yang Yanping , Li Jianhua
Published: November 2021

Introduction

Intermittent pneumatic compression (IPC) has been used for venous thrombosis (VTE) prevention. It’s necessary to evaluate the effects and safety of intraoperative use of IPC devices in the prevention of VTE in surgical patients.

Material and methods

Two authors independently searched the PubMed, Cochrane Library, MedLine, EMbase, China national knowledge infrastructure (CNKI), Wanfang databases for randomized controlled trials (RCTs) and cohort studies on the use of IPC in surgical patients up to June 10, 2021. The Cochrane Collaborations risk of bias tool and Newcastle-Ottawa Scale (NOS) were used for quality assessment. RevMan 5.3 software were used for statistical analyses.

Results

A total of 13 studies including seven RCTs and six retrospective cohort studies involving 6673 surgical patients were included, 1883 patients underwent IPC intervention. The synthesized RCT results indicated that IPC was beneficial to the reduce the incidence of DVT (RR0.30, 95%CI0.22~0.40, P<0.001) and VTE (RR0.51, 95%CI0.27~0.95, P=0.03). The synthesized results from retrospective cohort studies indicated that IPC is beneficial to the reduce the incidence of DVT (RR0.63, 95%CI0.42~0.96, P=0.03) and PE (RR0.34, 95%CI0.16~0.72, P=0.005). No significant publication biases were found for all synthesized outcomes (all p>0.05).

Conclusions

IPC seems to be safe and effective in the prevention and management of intraoperative VTE. Limited by sample size, this conclusion still needs to be further confirmed by large-sample, multi-center, high-quality clinical studies.
Mehrweg-PET auch für sensible Getränke?
Authors: Röhl Thomas
Published: November 2021

Die Quote ist nach wie vor mies. Im Verpackungsmarkt für Getränke spielen Mehrweg-PET-Behälter eine eher untergeordnete Rolle. Zu Unrecht, belegt nun ein gemeinsames Forschungsprojekt von Krones und Alpla.
Global, digital und nachhaltig
Authors: Sachs Melanie
Published: November 2021

60 Jahre nach Unternehmensgründung versteht sich Multivac längst nicht mehr als reiner Verpackungsmaschinenbauer. Das Unternehmen hat sich zu einem global tätigen Systemanbieter mit einem Jahresumsatz von 1,2 Milliarden Euro entwickelt. Und betritt neue Pfade im Bereich der Digitalisierung und der Nachhaltigkeit. Ein Gespräch mit Guido Spix, Geschäftsführender Direktor bei Multivac.
Etikettierer-Roboter-Kollaboration
Authors: Röhl Thomas
Published: November 2021

MDF-Platten befinden sich nicht nur an Wänden, Decken und Fußböden. Sie dienen auch als Möbelfronten und Tischplatten – und wollen auch gekennzeichnet werden. Und hier kommt eine pfiffige Etikettier-Roboter-Kollaboration zum Einsatz.
Aldi verliert den Anschluss
Authors: Schulz Hans-Jürgen , Stockburger Manfred
Published: November 2021

Aldi verliert Umsatz, Marktanteile und kämpft mit der Warenversorgung. Es zeichnet sich ab, dass der Discounter die Corona-Zuwächse aus dem Vorjahr dieses Jahr wieder einbüßen könnte. Die Konkurrenz entwickelt sich besser.
Vorbildlicher Auftritt
Authors: Krönert Alrun
Published: November 2021

Auf den Hund gekommen ist Laura Arendt erst zu Jahresbeginn. Sein Vertrauen hat sie sich geduldig erarbeitet. Ebenso ihren Erfolg im Job. Als Verkaufsleiterin bei Lidl schlägt ihr Herz vor allem fürs Team.
Sephora disponiert mit Relex
Authors: Rode Jörg
Published: November 2021

Der Markt für Auto-Dispo-Software ist in Bewegung. Das relativ junge Unternehmen Relex hat jetzt die Parfümerie-Kette Sephora mit ihren über 2500 Filialen als Kunden gewonnen. In diesem Sektor haben auch Douglas, Drogerie Müller und Rossmann das Prognose-System von Relex eingeführt.
Differenzierung durch Umsatzverzicht
Authors: Nusser Bernd
Published: November 2021

Er ist bekannt für seine prägnante Sicht auf die Dinge. Im exklusiven LZ-Interview mahnt David Bosshart zum massiven Umdenken auf allen Ebenen. „Es wird nicht ohne Verzicht gehen“, so die Botschaft des früheren CEO des Gottlieb-Duttweiler-Instituts.
Frostas Abschied vom Plastikbeutel zieht sich hin
Authors: Wenzel Horst
Published: November 2021

Die Umstellung des Beutel-Sortiments vom Packmaterial Kunststoff auf Papier verlangt Frosta mehr Zeit und Aufwand ab als ursprünglich geplant. Gleichwohl steht der TK-Spezialist fest zu seinem Vorhaben.
Vöslauer hat ehrgeizige Ziele
Authors: Hillemeyer Judit
Published: November 2021

Vöslauer verfolgt ambitionierte Nachhaltigkeitsziele bis zum Jahr 2030. CO2-Emissionen sollen sukzessive im Energie- und Verkehrsbereich gesenkt werden.
Ölz fördert Job-Fahrrad
Authors: Hillemeyer Judit
Published: November 2021

Der Backwarenproduzent Ölz engagiert sich für Umweltschutz. Mit einer Jobrad-Aktion werden Mitarbeitende finanziell beim Kauf eines Fahrrads unterstützt. Damit sollen sie möglichst zur Arbeit kommen. Die Kampagne wird im kommenden Jahr wiederholt.
Cyber-Angriff trifft Media-Saturn
Authors: Rode Jörg
Published: November 2021

Die folgenschwere Cyber-Attacke auf die IT von Media-Markt-Saturn unterstreicht, wie hoch das Risiko für große Händler geworden ist. Der Omni-Channel-Retailer kann kein Click&Collect für seinen Web-Shop anbieten. In den Filialen laufen die Kassen im Offline-Modus.
Tiktok-Video aus dem Kühlschrank
Authors: Nusser Bernd
Published: November 2021

Die Initiative Milch nutzt für ihre Aufklärungskampagne auch ungewöhnliche Orte und liefert Jugendlichen eine Kulisse für ihre Fotos und Videos.
Rewe-Azubis verkaufen im Zug
Authors: Biester Silke
Published: November 2021

Mit der Eröffnung eines Supermarktes im Zug fokussiert Rewe Mitte die Themen Ausbildung, Regionalität und Nachhaltigkeit.
Großbäcker bangen um Wertschöpfungspartnerschaft
Authors: Wessel Andrea
Published: November 2021

Nicht ohne Sorge schauen die deutschen Großbäcker auf die aktuelle Kostenexplosion für Energie und Rohstoffe. Der Verband warnt vor einem Abschmelzen der Substanz.
FrieslandCampina ist weniger mehr
Authors: Murmann Christoph
Published: November 2021

FrieslandCampina vermindert gezielt den Umsatz und die Verarbeitungsmenge. Die bäuerlichen Eigentümer des größten Milchverarbeiters Europas verlangen mehr Rendite. In Deutschland sieht man sich dank Landliebe, Chocomel und Valess auf dem Weg aus der Verlustzone.
Grenzwertig
Authors: Kemle Jens
Published: November 2021

Der Verkauf cannabishaltiger Lebensmittel in Deutschland unterliegt vielen Vorschriften. Wie komplex der Sachverhalt werden kann, zeigt der Streit zwischen Lidl und dem Hersteller Euphoria um angeblich erhöhte THC-Werte. Beide sehen sich im Recht. Jens Kemle
„GS1 Digital Link“ wird zu vielen Infos führen
Authors: Rode Jörg
Published: November 2021

Wichtige Player der FMCG-Branche kommen mit dem neuen QR-Code-System „GS1 Digital Link“ voran. Walmart und P&G loben einen Praxis-Test. C&A nutzt den Standard bereits. Das System erlaubt Firmen, von einem genormten QRCode aus auf eine Vielzahl nützlicher Informationen zu verlinken – für Verbraucher und B2B.
O&G-Sektor hat Reformbedarf
Authors: Heimig Dieter
Published: November 2021

Die griechischen Obst- und Gemüseerzeuger haben die Exporte im vergangenen Jahr um mehr als sechs Prozent steigern können.
Trienon rechnet mit weiterer Erlössteigerung
Authors: Heimig Dieter
Published: November 2021

Trienon ist seit fast drei Jahrzehnten mit landestypischen Spezialitäten aus dem gesamten Mittelmeerraum und vor allem mit Produkten aus Griechenland erfolgreich.
Paliria bekommt neue Submarke
Authors: Heimig Dieter
Published: November 2021

Feinkost Dittmann ist mit der griechischen Marke Paliria gut unterwegs. Im laufenden Jahr erzielt das Unternehmen ein Absatzplus von mehr als 39 Prozent.
Intravitreal injections during the COVID-19 pandemic era
Authors: Celik Dulger Selda , Citirik Mehmet , Bahadir Camgoz Esra , Yasin Teke Mehmet
Published: November 2021

Background: This study aimed to evaluate the clinical characteristics and changes in the number of patients receiving intravitreal injections (IVIs) at a tertiary hospital during the coronavirus disease 2019 (COVID-19) pandemic as compared to the pre-pandemic period.

Methods: This retrospective, cross-sectional study included 3,211 patients with retinal disease, who received IVIs of anti-vascular endothelial growth factor (anti-VEGF) between January and May 2020. This 5-month period was divided into a pre-pandemic and a pandemic period. Clinical and demographic data were collected and were compared between the patients in each period. All COVID-19 infection precautions were implemented to minimize the potential transmission of COVID-19 to both healthcare workers and patients.

Results: A total of 3,211 IVIs were administered to patients with diabetic retinopathy, age-related macular degeneration, retinal vein occlusion, and other retinal conditions. Diabetic retinopathy was the most common indication for treatment in the pre-pandemic as well as pandemic periods. Bevacizumab (Avastin, Roche) was the most common IVI type, followed by aflibercept (Eylea, Bayer). Of 3,211 IVIs, 2,943 (91.7%) were administered during the pre-pandemic period and 268 (8.3%) during the pandemic period. There was a statistically significant decrease in injections between the pre-pandemic and pandemic periods, with an overall reduction of 90.8% in IVIs (P < 0.05). No cases of confirmed transmission of COVID-19 orcomplications associated with IVIs were recorded.

Conclusions: This study showed that the number of IVIs and patient visits decreased significantly, by more than 10-fold, during the lockdown period. These findings show that COVID-19 has turned the management of sight-threatening eye diseases into a challenging process and must be addressed if future healthcarerestrictions are imposed.
Comparison of CSV-1000 and Metrovision contrast sensitivity tests in normal eyes
Authors: Tahkor Abolfazl , Heravian Shandiz Javad , Azimi Khorasani Abbas , Ansari Moghadam Alireza
Published: November 2021

Background: Measuring contrast sensitivity (CS) allows a better understanding of the visual performance of the human eye. This study aimed to examine the correlation and agreement between the results of two sinewave grating-based CS measurement methods, Metrovision and CSV-1000, in normal eyes.

Methods: This cross-sectional, comparative study was performed between December 2018 and April 2019, at an optometry clinic. Subjects underwent comprehensive ocular examinations, which included pupil reflexes, subjective refraction, external eye examinations, smooth pursuit eye movement assessment, the cover–uncover test, and detailed slit-lamp examination of the anterior and posterior segments. Metrovision and CSV-1000 were employed to assess CS under photopic conditions. The correlation and agreement of the results of the two tests were evaluated.

Results: CS was measured for 104 normal eyes for 3, 6, 12, and 18 cycles per degree (cpd) spatial frequencies (participants’ mean age ± standard deviation: 37.3 ± 26.4 years). The CSV-1000 measurements were significantly higher for the 3 and 6 cpd spatial frequencies (both P = 0.01); however, at higher spatial frequencies, CS scores were similar. The highest and lowest differences between the two tests were recorded for the 3 cpd spatial frequency and 18 cpd spatial frequency, respectively. Except for the 3 cpd spatial frequency, in both eyes, the findings correlated significantly between the CSV-1000 and Metrovision (P < 0.05). The narrowest and widest limits of agreement between the two tests were found for the 12 and 3 cpd spatial frequencies, respectively.

Conclusions: The CSV-1000 method estimated CS higher than the Metrovision method, mostly at lower spatial frequencies. Furthermore, the agreement between the two methods was greater at higher spatial frequencies than at lower frequencies. This should be kept in mind when using the two methods interchangeably in visual screening.
The potential retinal hazards of curing light use for dentists
Authors: Putnam Nicole M , Thomas Sara , Liao Grace , Bennett Emily , Breen Anne , Hueners Miranda , Korsten Lexi , Mills James , Mohsin Ibrahim , Poole Miles , Rookstool Shelby , Siddiqui Hala , Sommerfield Kelsie , Kozlowski Roni E , Mitchell John C , Mills Denise , Kozlowski Michael Robert
Published: November 2021

Background: Many recent studies have focused on the potential hazards of blue light exposure to ocular health. One group with a unique blue light exposure risk is dentists, who use curing lights that emit intense blue light during restorative procedures. During these procedures, dentists often experience brief ocular exposure to these lights. The purpose of the present study was to explore whether such exposures may have an effect on the vision and ocular health of dentists.

Methods: A group of 12 dentists who had experienced curing light exposure over a period of 10 or more years were compared to a group of eight control subjects with no such exposure. The subjects were tested for visual acuity and contrast sensitivity. Their retinas were examined using fundus imaging and optical coherence tomography. Macular pigment optical density was measured. The likelihood that brief blue light exposure could lead to ocular effects was further explored by subjecting a retinal pigment epithelial cell (RPE) line to such exposures.

Results: Although no visual defects or ocular pathologies were found in either group, the dentist group differed from the control group in having increased macular thickness (P < 0.02), a higher incidence of macular vessel tortuosity (P < 0.05), and greater variance in their macular pigment optical density values (P < 0.01). RPE cells that received blue light exposure similar to those sustained by dentists demonstrated a change in physiology.

Conclusions: Retinal changes were found in dentists, which, while not pathological in themselves, are associated with some retinal pathologies. Further studies are necessary to determine whether these signs correlate with the degree of curing light exposure and to determine whether they eventually develop into pathological conditions.
Comparison of visual aids for improving reading performance in children with dyslexia
Authors: Omar Rokiah , Buari Noor Halilah , Majumder Chiranjib , Feizal Knight Victor
Published: November 2021

Background: Dyslexia is a key learning disorder associated with reading difficulties in children. The purpose of this study was to determine the effectiveness of simple visual devices in improving the reading performance of children with dyslexia.

Methods: A case?control study was conducted by selecting 80 school children with dyslexia, aged 8?11 years, from the Special Dyslexic School Program of the Ministry of Education (MOE) Malaysia. Subjects were randomly assigned to four groups: the typoscope, magnifier, visual tracking magnifier (VTM), and control groups. Reading performance was measured based on reading speed and reading error rate. The time taken to complete reading of text was measured, and reading errors were recorded. The reading performance of each group was assessed at baseline, week 2, week 6, and week 12.

Results: Reading performance was significantly different (P < 0.05) for both Level 1 and Level 2, before and after intervention only in children with dyslexia using magnifiers and VTM. Reading performance for children with dyslexia using a magnifier or a VTM increased significantly (P < 0.05) from baseline to week 2, week 6, and week 12. The improvement in reading speed was 2.5 times faster for children in the VTM group than in the other groups.

Conclusions: Simple visual aids, such as a VTM and magnifying glass, improved reading performance in children with dyslexia. The VTM intervention yielded the greatest improvement after 12 weeks of intervention. Hence, it is suggested that a VTM be used as part of a rehabilitation program for all children with dyslexia in Malaysia, particularly those in dyslexia programs in schools under the MOE Malaysia. However, future studies with longer follow-up periods are needed to confirm the sustainability of this improved reading performance after discontinuation of the intervention.
Teachers Challenges In The Using Of Blood Learning Media In Kids Garden
Authors: Olyvia Viona
Published: November 2021

Abstract This study aims to reveal the challenges of teachers in using online learning media and to find solutions that can be taken by teachers. In the current pandemic, teachers are required to be able to master technology, so that teachers can take advantage of various online media in learning. Currently, many PAUD teachers are confused about utilizing technology-based online media. Finally, in a simple way, the teacher gives written assignments through the WhatsApp group for parents to work on by children. This new activity requires teachers to have competence in operating technology to design and use appropriate learning media for children. Teachers are required to quickly adapt to technology so that teachers are able to use various applications to support online learning at. The research method used is a literature study where the data collection technique is through processing and analyzing various sources or references to scientific journals and books whose relevance with the problem to be studied. Data analysis relates problems to theories contained in scientific journals or appropriate books. The results of this study found that in the use of online learning media, there were several challenges for teachers such as the weak competence of teachers in mastering technology, the lack of facilities and infrastructure in utilizing various online learning media and the limited internet network in covering other online learning media. The solution that teachers can take is to conduct various trainings, webinars or workshops. Teachers can also take advantage of various training platforms provided by the Ministry of Education and Culture, free or paid.

Keywords: Teacher Challenges, Online Leraning Media, Early Childhood
Efficacy of combination of biofeedback therapy and pelvic floor muscle training in dyssynergic defecation
Authors: Özin Y , Öztürk Ö , Tenlik İ , Yüksel S , Bacaksız F , Arı D , Ramadan S.U. , Yalınkılıç Z.M.
Published: November 2021

Background: It is now known that with appropriate exercises, the functions of the muscles in the body ameliorate and increase in strength. We applied pelvic floor muscle relaxation training and exercises that strengthen the abdominal and pelvic muscles in combination with biofeedback therapy (BFT) to patients with dyssynergic defecation (DD).

Methods: Patients who met the criteria for DD and had no underlying organic cause were included in this study. The electromyography (EMG) technique was used for BFT therapy. Patients had received at least six sessions of BFT. BFT was considered successful in patients when the DD pattern in anorectal manometry (ARM) disappeared and/or adequate anal relaxation was obtained following BFT and in patients who had full clinical recovery.

Results: Data of 104 patients (58 females [55.8%] and 46 males [44.2%]) was evaluated. Abdominal and rectal symptoms disappeared in 71 (68.26%) patients. Of the patients who achieved symptomatic improvement, 58 (55.76%) saw a disappearance of the dyssynergic defecation pattern.

When the differences between anal sphincter pressures before and after treatment were compared in patients who responded to BFT and those who did not, no significant differences were observed, but significant changes were found in anal squeezing pressures. It was found that those who had high squeezing pressures before BFT, those who increased their squeezing pressures after BFT, and those who decreased their resting pressure responded better to BFT.

Conclusions: In this study, BFT was found to be more effective in those with a high squeezing pressure and those that increased squeezing pressure after BFT. These findings will influence the treatment of patients with dyssynergic defecation who do not respond to treatment. A combination of abdominal and pelvic floor muscle exercises and BFT increases patient response.
Overview towards improved understanding of the mechanisms leading to heavy precipitation in the western Mediterranean: lessons learned from HyMeX
Authors: Khodayar Samira , Davolio Silvio , Di Girolamo Paolo , Lebeaupin Brossier Cindy , Flaounas Emmanouil , Fourrie Nadia , Lee Keun-Ok , Ricard Didier , Vie Benoit , Bouttier Francois , Caldas-Alvarez Alberto , Ducrocq Veronique
Published: November 2021

Abstract. Heavy precipitation (HP) constitutes a major meteorological threat in the
western Mediterranean (WMed). Every year, recurrent events affect the area
with fatal consequences for infrastructure and personal losses. Despite this
being a well-known issue widely investigated in the past, open
questions still remain. Particularly, the understanding of the underlying
mechanisms and the modeling representation of the events must be improved.
One of the major goals of the Hydrological Cycle in the Mediterranean
Experiment (HyMeX; 2010–2020) has been to advance knowledge on this topic.
In this article, we present an overview of the most recent lessons learned
from HyMeX towards an improved understanding of the mechanisms leading to HP in the WMed. The unique network of instruments deployed as well as the use of finer model
resolutions and coupled models provided an unprecedented opportunity to
validate numerical model simulations, develop improved parameterizations,
and design high-resolution ensemble modeling approaches and sophisticated
assimilation techniques across scales. All in all, HyMeX, and particularly the science team heavy precipitation,
favored the evidencing of theoretical results, the enrichment of our
knowledge on the genesis and evolution of convection in a complex topography
environment, and the improvement of precipitation forecasts. Illustratively,
the intervention of cyclones and warm conveyor belts in the occurrence of
heavy precipitation has been pointed out, and the crucial role of the
spatiotemporal distribution of atmospheric water vapor for the
understanding and accurate forecast of the timing and location of deep
convection has been evidenced, as has the complex interaction among
processes across scales. The importance of soil and ocean conditions and the
interactions among systems were highlighted, and such systems were
specifically developed in the framework of HyMeX to improve the realism of
weather forecasts. Furthermore, the benefits of cross-disciplinary efforts
within HyMeX have been a key asset in bringing our knowledge
about heavy precipitation in the Mediterranean region a step forward.
Opioid Kullanım Bozukluğu Olan Hastalarda Gabapentin ve Pregabalin Kullanım Sıklığı
Authors: Çiçek Erdinç , Demirel Başak
Published: November 2021

Amaç: Bu çalışmanın amacı AMATEM polikliniğine opioid kullanımı nedeniyle başvuran hastalarda gabapentin ve pregabalin kullanım sıklığının araştırılmasıdır.
Yöntem: Çalışmaya halen opioid kullanan veya buprenorfin/ naloksan tedavisi alan 144 opioid kullanım bozukluğu olan hasta alındı.Yarı yapılandırılmış görüşme protokolü ile opioid ve gabapentinoid kullanımları değerlendirildi.
Bulgular:Yaşam boyu gabapentin ve pregabalin kullanım sıklığı sırasıyla %51,4 ve %50,7 olarak bulundu. Polikliniğe başvurduğu sırada hastaların %35,4’ü gabapentin, %26,4’ü pregabalin kullanıyordu. Buprenorfin/naloksan kullanan hastaların %46’sının hem pregabalin hem de gabapentin kullandığı bulundu. Folyo ile opioid kullanan hastalar ile damardan kullanan hastalar arasında gabapentinoid kullanım sıklığı arasında herhangi bir fark bulunmadı.
Sonuç: Opioid kullanım öyküsü olan hastaların gabapentinoid kötüye kullanımı için yüksek riskli bir grup oluşturduğu görülmektedir. Opioid kullanan hastaları takip eden hekimlerin kötüye kullanma riski olan hastalarda gabapentinoid reçete ederken dikkatli olmaları ve hastalara gabapentinoidlere alternatif ilaçlar önermeleri uygun olabilir.
Çevrimiçi Alışveriş Bağımlığı Ölçeğinin Türkçe Psikometrik Özelliklerinin İncelenmesi
Authors: Yılmaz Tuğba , İkiz Gizem , Avcı Furkan Mertcan
Published: November 2021

Amaç: Günümüzün en önemli problemlerinden biri olan çevrimiçi davranışsal bağımlılıklar araştırmacılar tarafından ölçülmeye çalışılmaktadır. İnsanların çevrimiçi alışveriş yapma şekli ve tutumları da bu bağlamda araştırılmaktadır. Bu çalışmada çevrimiçi alışveriş bağımlılığını ölçmek amacıyla geliştirilmiş olan bir ölçek olan Online Shopping Addiction Scale (OSA)’nın Türkçeye çeviri, uyarlanma ve geçerlik ve güvenirlik çalışmalarının yapılması amaçlanmıştır. Yöntem: Bu çalışma süresince bir ay ara ile iki farklı zaman diliminde ölçüm gerçekleştirilmiştir. İlk olarak 324 katılımcıya Çevrimiçi Alışveriş Bağımlılığı Ölçeği (ÇABÖ), Kompulsif Çevrimiçi Satın Alma Ölçeği ve Young İnternet Bağımlılığı Ölçeği-Kısa Form uygulanmıştır. İkinci ölçümde ise ilk ölçümlere katılan 110 katılımcıya Çevrimiçi Alışveriş Bağımlılığı Ölçeği uygulanmıştır.
Bulgular: Orijinalinde altı faktörlü bir ölçek olan ÇABÖ’nün Türkçe uyarlamasının ilk iki faktörün (belirginlik ve tolerans) birleşmesiyle beş faktörde toplandığı bulunmuştur. Ölçeğin iç tutarlık katsayısı .92, test tekrar-test güvenirliği .79 olarak bulunmuştır. Ölçeğin beş alt faktörünün iç tutarlık katsayılarının .40-.88 arasında değiştiği bulunmuştur. ÇABÖ’nün eş geçerliliği Young İnternet Bağımlılığı Ölçeği Kısa Form ve Kompulsif Çevrimiçi Satın Alma Ölçeği ile test edilmiş ve anlamlı sonuçlar elde edilmiştir.
Sonuç: Araştırmanın sonuçları Çevrimiçi Alışveriş Bağımlılığı Türkçe uyarlamasının geçerli ve güvenilir olduğunu göstermektedir.
COVID-19 Kısıtlamaları Sürecinde Üniversite Öğrencilerinde Sosyal Medya Bağımlılığı ve Temel Psikolojik İhtiyaçlar Arasındaki İlişkinin İncelenmesi
Authors: Bozkurt İlhan , Bozkurt Öznur
Published: November 2021

Amaç: Bu çalışmada, COVID-19 salgın sürecinde üniversite öğrencilerinin sosyal medya bağımlılığı düzeyi ile temel psikolojik ihtiyaçlarının karşılanma düzeyi arasındaki ilişkinin incelenmesi amaçlanmıştır.
Yöntem: Çalışmada nicel araştırma yöntemi kullanılmış ve bağımlı ve bağımsız değişkenlerin arasındaki ilişki, korelasyonel desen tercih edilerek incelenmiştir. Bir kamu üniversitesinde lisans eğitimi alan öğrenciler araştırmanın evrenini oluşturmuştur. Bu evrenden kolayda örneklem yöntemi ile 508 kişilik örneklem oluşturulmuştur. Araştırma verilerinin toplanması için; Sosyodemografik Veri Formu, Üniversite Öğrencileri Temel İhtiyaçlar Ölçeği (ÜÖTİÖ) ve Sosyal Medya Bağımlılığı Ölçeği (SMBÖ-YF) kullanılmıştır.
Bulgular: Sosyal medya bağımlılığı ve temel psikolojik ihtiyaçların karşılanma düzeyi sosyodemografik değişkenlere ve sosyal medya kullanım alışkanlıklarına göre farklılaşmaktadır. Ayrıca katılımcılar COVID-19 salgın sürecinde, sosyal medya kullanımlarının arttığını ifade etmişlerdir. Bu süreçte sosyal medya kullanım sürelerinin arttığını belirten katılımcıların, diğer katılımcılara göre anlamlı olarak daha yükse sosyal medya bağımlılık düzeyi gösterdikleri belirlenmiştir.
Sonuç: Bazı temel psikolojik ihtiyaçların yeterince karşılanmaması sosyal medya bağımlılığı düzeyini artırırken; yeterince karşılanması ise azaltmaktadır. Salgın sürecinde üniversite öğrencilerinin sosyal medya kullanım oranları artmıştır. Bu süreçte sosyal medya kullanımı artanların sosyal medya bağımlılığı düzeyi de yüksek bulunmuştur.