bluuebunny/crossref_metadata_2025 huggingface dataset:
Institutions and Moral Demandingness
Authors: Belic Jelena
Published: March 2022

How much should we sacrifice for the sake of others? While some argue in favour of significant sacrifices, others contend that morality cannot demand too much from individuals. Recently, the debate has taken a new turn by focusing on moral demands under non-ideal conditions in which the essential interests of many people are set back. Under such conditions, in some views, moral theories must require extreme moral demands as anything less is incompatible with equal consideration of everyone’s interests. The insistence on the extremeness of moral demands, however, presupposes a simplistic account of non-ideal conditions as characterized mainly by the non-compliance of many individuals. Non-ideal conditions are also characterized by institutional non-compliance, whereby institutions often do not do what they ought to do. Institutional non-compliance is significant as it increases the size of moral demands significantly, thereby exacerbating the conflict between these demands and the self-interest of individuals subjected to these institutions. I argue that individuals have a meta-interest in not experiencing such internal conflicts as these can undermine their affirmation of self-respect. Meta-interest can be advanced by adopting the promotion of just institutions as an ultimate aim, as such institutions lessen the conflict and, accordingly, enable us to live more harmonious lives. Moreover, the promotion of just institutions allows us to affirm our sense of self-respect under non-ideal conditions too. Because the promotion of just institutions is in our self-interest, this is not an extreme but a moderate moral demand.
The role of relaxation and retardation phenomenon of Oldroyd-B fluid flow through Stehfest’s and Tzou’s algorithms
Authors: Awan Aziz Ullah , Riaz Samia , Abro Kashif Ali , Siddiqa Ayesha , Ali Qasim
Published: March 2022

Delayed response (delay of the elasticity) and time needed for initial stress can lead to relaxation and retardation phenomenon; this is because of the consistent behavior of viscoelastic fluid on thermodynamic principles. In this context, the aim of this article is to investigate the unsteady, incompressible, and Oldroyd-B viscoelastic fluid under wall slip conditions to know the hidden aspects of relaxation and retardation. The motion of the liquid is assumed over a flat vertical plate which moves through an oscillating velocity. A fractional model is developed by using the modern definition of the non-singular kernel proposed by Caputo and Fabrizio. We have obtained a semi-analytical solution of the non-dimensional model by using the Laplace transformation that satisfies our imposed suitable boundary conditions. We have tackled the Laplace inverse by employing Stehfest’s and Tzou’s algorithms. The velocity is enhanced by decreasing the estimations of relaxation time λ as well as slip parameter, and the temperature is also increasing for a considerable measure of the fractional factor. The effects of different fractional and physical parameters are plotted using Mathcad software based on the relaxation and retardation phenomenon of Oldroyd-B viscoelastic fluid.
Covid-19 und das Arbeitsmarktverhalten von Frauen und Männern
Authors: Tertilt Michèle
Published: March 2022

In Folge von Covid-19 sind bisher mehr Männer als Frauen gestorben.1 Aber wirtschaftlich sind Frauen von der Pandemie stärker betroffen als Männer. In ihrer Thünen-Vorlesung vor dem Verein für Socialpolitik im Herbst 2021 erläutert Michèle Tertilt die Auswirkungen der Corona-Pandemie auf das Arbeitsmarktverhalten von Frauen und Männern und die sich dadurch ergebenden langfristigen Konsequenzen. Tertilt berichtet zunächst von einer empirischen Studie, in der sie gemeinsam mit Koautoren untersucht hat, inwieweit sich das relative Arbeitsangebot von Frauen und Männern in der Pandemie in einer Reihe von Ländern verändert hat. Sie stellt außerdem Ergebnisse eines quantitativen Modells vor, das die mittel- und langfristigen Konsequenzen der Pandemie für die Geschlechtergerechtigkeit am Arbeitsmarkt und insbesondere für das Lohngefälle vorhersagen soll.
Nextness and story organization: ‘my day’ sequences in parent-child interaction
Authors: Kim Younhee , Carlin Andrew P.
Published: March 2022

In this paper we offer a longitudinal Conversation Analysis of talk lasting 18 months between a father and son, which reveals changes in the child’s level of Interactional Competence (IC). We propose an index of developing IC based upon Sacks’ distinction between “invited” and “volunteered” stories. While stories have a “socialization function” we suggest stories may be tracked in terms of IC also. What has been called “today narrative” routines (“What did you do at school today”, etc.), initiated by the father, predominate in a series of conversations. The analysis reveals how the child is encouraged to take extended turns through the father’s questions and comments, which are developed into a storytelling sequence. We observe that the child’s responses to the initial inquiries become more elaborate over time. Furthermore, there is a gradual resistance to the invited story format because it inhibits how the child organizes his stories. Volunteered stories obtain a more personal ‘voice’. The paper showcases the nexus between socialization and interactional competence.
In the Shackles of Instability: Challenges of Operation Barkhane in the G5 Sahel Countries
Authors: Godó Judit
Published: March 2022

Suffering from a multidimensional crisis, the Sahel has morphed into the new center of terror. In the past few years, it has become one of the most hazardous places in the world, which has negatively transformed the fragile states of the Western-African region. Emerging as a novel security policy challenge, the G5 Sahel countries – namely Burkina Faso, Chad, Mali, Mauritania, and Niger – have found themselves stuck in a quagmire of different deep-rooted human security issues, which have placed their populations in a vicious circle of closely intertwined problems. Various influences threaten not just the security of residents and foreign actors but also the security of neighboring states. Different regional and international actors are trying to solve this complex crisis with varying levels of success. In this environment, in the shackles of instability, the presence of jihadist terrorist organizations and the operations of different rebel armed forces independent from governments pose a growing threat by making Sahelian life a living hell. This paper aims to discuss the challenges and effectiveness of Operation Barkhane, the terminating counter-terrorism operation led by the French, which has started its strategical transformation by merging into the European initiative known as the Takuba Task Force. Under President Emmanuel Macron, France remains the most important actor in the international community. In close alliance and cooperation with the African leaders and military forces of the five countries involved, they have been fighting terrorism within the confines of Operation Barkhane since 2014. Until recently 5,100 French soldiers have been deployed. They risk their lives every day in an incredibly hostile and constantly changing field where either they or the jihadists are under fire. Even though this operation has become an essential part of providing security in these countries, French participation remains controversial: despite their willingness to help, heavily armed French soldiers are not the most popular throughout the region. The importance of the topic speaks for itself because the transformation of the operation and the withdrawal of half of the French troops may have a drastic impact on the future of the Sahel.
Representaciones conceptuales multimedia de los ámbitos de actuación en educación social elaborados por estudiantes universitarios (2015-2018)
Authors: López Meneses Eloy , Vázquez Cano Esteban , Fernández Márquez Esther , López Belmonte Jesús
Published: March 2022

El presente estudio emana del proyecto Innovación docente 2.0 con Tecnologías de la Información y la Comunicación en el Espacio Europeo de Educación Superior, desarrollado en el marco de los Proyectos de Innovación y Desarrollo Docente de la Universidad Pablo de Olavide (UPO), financiado por el Vicerrectorado de Docencia y Convergencia Europea de dicha Universidad. La investigación describe un estudio diacrónico sobre las concepciones acerca de los ámbitos propios de la Educación Social mediante la elaboración de mapas conceptuales multimedia. El desarrollo de la misma plantea un carácter innovador y se desarrolla con 266 estudiantes pertenecientes a los cursos de Grado de Educación Social y Doble Grado de Educación Social y Trabajo Social de la Universidad Pablo de Olavide, durante los cursos académicos 2015/16, 2016/17 y 2017/2018. A través de una metodología cualitativa, mediante técnicas de etnografía virtual y cuantitativa, se analizaron los ámbitos de intervención en Educación Social y Trabajo Social con los siguientes resultados: personas con discapacidad y salud mental (15,37%), drogodependencia (14,70%), tercera edad (14,03%), adultos (11,25%), infancia (9,47%), inmigración (8,35%), animación sociocultural (7,57%), violencia de género (6,12%) y adolescencia (4,34%).
ENSEÑANZA DEL INGLÉS EN EDUCACIÓN RURAL: ERCILLA- COLLIPULLI, CHILE
Authors: Anríquez Ponce Gabriel Eduardo
Published: March 2022

Esta investigación tiene por objeto describir las prácticas profesionales que realizan los docentes en la Red de Inglés Ercilla- Collipulli Rural English Net, pertenecientes a escuelas municipales y particulares subvencionadas de las comunas de Ercilla y Collipulli, en Chile, y determinar los factores que influyen en el éxito o fracaso del uso del recurso educativo denominado It’s my turn. Para dar cumplimiento al objetivo fueron entrevistados un total de diecinueve profesores. Los resultados obtenidos dan cuenta que el trabajo realizado en este espacio constituye una práctica consolidada, lo que les permitió establecer las fortalezas y debilidades del grupo. Entre sus fortalezas se encuentran el intercambio de experiencias, la transposición al aula de lo trabajado en laRed, la mejora en la disposición de los docentes para enfrentar la enseñanza del idiomainglés, la responsabilidad frente a los compromisos, la valoración por las opiniones divergentes, la sistematización de sus prácticas y el compromiso del coordinador de la red en todas las actividades realizadas, mientras que entre sus debilidades reconocen la falta de acompañamiento constante por parte del PIAP, la distancia entre las escuelasparticipantes y el lugar de reunión y la poca formación en el idioma inglés por parte de los profesores que integran la Red. En relación a los factores que influyen en el éxito o fracaso del uso del recurso educativo denominado It’s my turn se desprende que es esencial para el éxito la disposición para emplear el material y la confianza en sus capacidades profesionales.
KCNQ Channels Enable Reliable Presynaptic Spiking and Synaptic Transmission at High Frequency
Authors: Zhang Yihui , Li Dainan , Darwish Youad , Fu Xin , Trussell Laurence O. , Huang Hai
Published: March 2022

The presynaptic action potential (AP) is required to drive calcium influx into nerve terminals, resulting in neurotransmitter release. Accordingly, the AP waveform is crucial in determining the timing and strength of synaptic transmission. The calyx of Held nerve terminals of rats of either sex showed minimum changes in AP waveform during high-frequency AP firing. We found that the stability of the calyceal AP waveform requires KCNQ (KV7) K+channel activation during high-frequency spiking activity. High-frequency presynaptic spikes gradually led to accumulation of KCNQ channels in open states which kept interspike membrane potential sufficiently negative to maintain Na+channel availability. Blocking KCNQ channels during stimulus trains led to inactivation of presynaptic Na+, and to a lesser extent KV1 channels, thereby reducing the AP amplitude and broadening AP duration. Moreover, blocking KCNQ channels disrupted the stable calcium influx and glutamate release required for reliable synaptic transmission at high frequency. Thus, while KCNQ channels are generally thought to prevent hyperactivity of neurons, we find that in axon terminals these channels function to facilitate reliable high-frequency synaptic signaling needed for sensory information processing.

SIGNIFICANCE STATEMENTThe presynaptic spike results in calcium influx required for neurotransmitter release. For this reason, the spike waveform is crucial in determining the timing and strength of synaptic transmission. Auditory information is encoded by spikes phase locked to sound frequency at high rates. The calyx of Held nerve terminals in the auditory brainstem show minimum changes in spike waveform during high-frequency spike firing. We found that activation of KCNQ K+channel builds up during high-frequency firing and its activation helps to maintain a stable spike waveform and reliable synaptic transmission. While KCNQ channels are generally thought to prevent hyperexcitability of neurons, we find that in axon terminals these channels function to facilitate high-frequency synaptic signaling during auditory information processing.
Opioid-Induced Pronociceptive Signaling in the Gastrointestinal Tract Is Mediated by Delta-Opioid Receptor Signaling
Authors: Jaramillo-Polanco Josue , Lopez-Lopez Cintya , Yu Yang , Neary Emma , Hegron Alan , Canals Meritxell , Bunnett Nigel W. , Reed David E. , Lomax Alan E. , Vanner Stephen J.
Published: March 2022

Opioid tolerance (OT) leads to dose escalation and serious side effects, including opioid-induced hyperalgesia (OIH). We sought to better understand the mechanisms underlying this event in the gastrointestinal tract. Chronicin vivoadministration of morphine by intraperitoneal injection in male C57BL/6 mice evoked tolerance and evidence of OIH in an assay of colonic afferent nerve mechanosensitivity; this was inhibited by the δ-opioid receptor (DOPr) antagonist naltrindole when intraperitoneally injected in previous morphine administration. Patch-clamp studies of DRG neurons following overnight incubation with high concentrations of morphine, the µ-opioid receptors (MOPr) agonist [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin (DAMGO) or the DOPr agonist [D-Ala2, D-Leu5]-Enkephalin evoked hyperexcitability. The pronociceptive actions of these opioids were blocked by the DOPr antagonist SDM25N but not the MOPr antagonist D-Pen-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2. The hyperexcitability induced by DAMGO was reversed after a 1 h washout, but reapplication of low concentrations of DAMGO or [D-Ala2, D-Leu5]-Enkephalin restored the hyperexcitability, an effect mediated by protein kinase C. DOPr-dependent DRG neuron hyperexcitability was blocked by the endocytosis inhibitor Pitstop 2, and the weakly internalizing DOPr agonist ARM390 did not cause hyperexcitability. Bioluminescence resonance energy transfer studies in HEK cells showed no evidence of switching of G-protein signaling from Gito a Gspathway in response to either high concentrations or overnight incubation of opioids. Thus, chronic high-dose opioid exposure leads to opioid tolerance and features of OIH in the colon. This action is mediated by DOPr signaling and is dependent on receptor endocytosis and downstream protein kinase C signaling.

SIGNIFICANCE STATEMENTOpioids are effective in the treatment of abdominal pain, but escalating doses can lead to opioid tolerance and potentially opioid-induced hyperalgesia. We found that δ-opioid receptor (DOPr) plays a central role in the development of opioid tolerance and opioid-induced hyperalgesia in colonic afferent nociceptors following prolonged exposure to high concentrations of MOPr or DOPr agonists. Furthermore, the role of DOPr was dependent on OPr internalization and activation of a protein kinase C signaling pathway. Thus, targeting DOPr or key components of the downstream signaling pathway could mitigate adverse side effects by opioids.
The Coattail Effect in Multiparty Presidential Elections
Authors: Hanan Djayadi , Irvani Deni
Published: March 2022

Many studies have been conducted about the presidential coattail effect in presidential democracies, but few have considered multiparty presidential elections. These few studies find that the effect does exist in multiparty presidential elections but their effect is unevenly distributed among the members of the party coalitions that nominate the presidential candidate. We follow these theoretical insights by presenting the case of Indonesia, the world’s largest multiparty presidential democracy. Using election result data and national survey data, including experimental surveys, we find that in Indonesia the size and direction of the presidential coattail effect depend on whether the party is a core or peripheral member of the coalition, its role in the coalition, and its size.
Is a “Silent Revolution” in the Making in China?
Authors: Chen Jie , Huhe Narisong , Yan Ting
Published: March 2022

Five decades ago, Inglehart for the first time described and explained an unprecedented transformation of political cultures in advanced industrial societies, which he called the “silent revolution.” It was characterized by the emergence in those countries of postmaterialist values as the result of a sustained period of economic growth, and the profound impact of those values on people’s political attitudes and behavior. As China has experienced extraordinary economic growth in the past several decades, has such a “silent revolution” happened there? The answer to this question has been far from complete or clear. Using three longitudinal, cross-sectional national surveys, we find that while the current level of postmaterialist values in China remains relatively low, such values have flourished among younger people, and those values do shape political attitudes and behavior.
La metarretórica cognitiva aristotélica y su relación con el tratamiento de la memoria en la Rhetorica ad Herennium
Authors: Iglesias-Crespo Carlos
Published: March 2022

This article examines the influence exerted by the Aristotelian cognitive metarhetoric over the treatment of memory in Book 3 of the Rhetorica ad Herennium. Sections 3.16.28–29, 3.19.32 and 3.22.35–37 are read against the backdrop of the core principles of Aristotle’s psychological treatises on mind and memory, De Anima and De Memoria et Reminiscentia, together with the multifaceted concept of energeia, found in these treatises as well as in the Rhetoric and the Metaphysics. The results suggest that the psychology of memory of the Rhetorica ad Herennium and its rhetorical products are indebted to Aristotelian philosophy, with particular emphasis on the imagines agentes within the mnemonic system per locos et imagines.
Primary hyperaldosteronism induces congruent alterations of sodium homeostasis in different skeletal muscles: a 23Na-MRI study
Authors: Christa Martin , Hahner Stefanie , Köstler Herbert , Bauer Wolfgang Rudolf , Störk Stefan , Weng Andreas Max
Published: March 2022

Background

Sodium homeostasis is disrupted in many cardiovascular diseases, which makes non-invasive sodium storage assessment desirable. In this regard, sodium MRI has shown its potential to reveal differences in sodium content between healthy and diseased tissues as well as treatment-related changes of sodium content. When different tissues are affected disparately, simultaneous assessment of these compartments is expected to provide better information about sodium distribution, reduce examination time, and improve clinical efficiency.

Objectives

The objectives were (1) to investigate sodium storage levels in calf and pectoral muscle in healthy controls and patients and quantify changes following medical treatment and (2) to demonstrate homogeneous disruption in skeletal muscle sodium storage in patients with primary hyperaldosteronism (PHA).

Methods

We assessed sodium storage levels (relative sodium signal intensity, rSSI) in the calf and pectoral muscles of eight patients with PHA prior and after treatment and 12 age- and sex-matched healthy volunteers.

Results

Calf and pectoral muscle compartments exhibited similar sodium content both in healthy subjects (calf vs pectoral rSSI: 0.14 ± 0.01 vs 0.14 ± 0.03) and PHA patients (calf vs pectoral rSSI: 0.19 ± 0.03 vs 0.18 ± 0.03). Further, we observed similar treatment-related changes in pectoral and calf muscles in the patients (proportional rSSI change calf: 26%; pectoral: 28%).

Conclusion

We found that sodium was distributed uniformly and behaved equally in different skeletal muscles in Conn’s syndrome. This allows to measure both heart and skeletal muscle sodium signals simultaneously by a single measurement without repositioning the patient. This increases 23Na-MRI’s clinical feasibility as an innovative technique to monitor sodium storage.
La inserción del fonema /rˇ/ en el quechua actual: una explicación desde una teoría de las clases naturales
Authors: Meneses Tutaya Norma
Published: March 2022

En el presente estudio se plantea una explicación probable de la inserción de la vibrante múltiple prepalatal

/ř/ como un segmento «natural» en el inventario fonológico del quechua actual pese a la evidencia de que se deriva del contacto con el español. Es decir, que el fonema /ř/ ha sido incorporado al sistema fonológico de algunos dialectos quechuas y está en proceso de estarlo en otros, debido fundamentalmente a que corresponde a una posición «naturalmente aceptable» dentro del sistema del quechua más que a un préstamo o a una interferencia del español andino. En todo caso, sin dejar de lado ambas explicaciones, planteo que el factor determinante es intrínseco al sistema fonológico del quechua y que esto se explica desde un enfoque que denomino teoría de las clases naturales. Por este concepto, el sistema consonántico del quechua está organizado en subsistemas de clases naturales donde prevalece la clase [+cons, +cor] en cuyo interior se produce la oposición entre las subclases [+cons, +cor, +ant] / [+cons, +cor, +post]. La presencia de la vibrante múltiple retrofleja se explicaría por su reubicación en la segunda subclase donde rellena una casilla vacía.
Análisis fonético-fonológico de la formación de hipocorísticos en Singa (Huamalíes-Huánuco)
Authors: Mere Collazos Milagros Jessica
Published: March 2022

La presente investigación se enfoca en la descripción de los procesos fonético-fonológicos que intervienen en la formación de hipocorísticos en el distrito de Singa, lugar en el que existe contacto lingüístico entre el quechua y el castellano. El estudio se fundamenta en las bases teóricas de la onomástica, la afectividad lingüística y el contacto de lenguas. A partir del análisis, se determinó que uno de los procedimientos más frecuentes y que evidencia influencia quechua es el alzamiento vocálico de /e/ y /o/, así como la palatalización.
Los valores de la cultura andina y una reflexión sobre la necesidad de su cultivo formal a través de la EIB
Authors: Meneses Tutaya Norma
Published: March 2022

Basándonos en un análisis semántico-discursivo de las entrevistas realizadas a un conjunto variado de personas, que se autoidentifican de la cultura andina, sobre cuáles son los valores más importantes que sirven para determinar la integridad de una persona, se puede concluir que los cinco valores fundamentales de la cultura andina en orden de jerarquía son: laboriosidad, humildad, responsabilidad, reciprocidad y solidaridad. Cabe anotar que no se trata de valores privativos de esta cultura.

La reflexión final es que toda educación formal debe estar orientada al cultivo de los valores y los principios cognoscitivos de la cultura propia de cada pueblo que se materializan en todo su acervo, es decir, a coadyuvar el cumplimiento del proceso de enculturación y socialización de las nuevas generaciones. Puesto que la actual sociedad peruana es pluricultural y multilingüe _ya que contiene pueblos con distintos esquemas gnoseológico-axiológicos que hasta la actualidad conviven en una relación conflictiva de dominación-resistencia_ es necesario que todo el sistema de la educación formal del país sea intercultural y bilingüe.
Memorias de una monolingüe
Authors: Castro Tenorio Sintia Pilar
Published: March 2022

El presente artículo aborda la situación lingüística de una quechuahablante en el ámbito social a través de su historia personal. Dentro de este marco se estudia temas como las actitudes lingüísticas, el bilingüismo, la identidad, entre otros. Asimismo, se trabajó con memorias de otras quechua-hablantes, quiénes han sido personajes importantes dentro del marco político y social del Perú. La investigación concluye que la evaluación microsocial de la documentación de las memorias de personas quechuahablantes es fundamental para tener posteriormente un panorama general de la situación del quechua y de cómo ésta ha ido perdiendo su prestigio dentro del mismo grupo que la habla.
Estudio de los sufijos del Manuscrito Quechua de Huarochirí (s. XVI) Study of the suffixes in the Huarochiri Manuscript (16th century)
Authors: Baldoceda Espinoza Ana , Huanca Quispe Jaime , Chalco Arangoitia Walter , Solís Aroni Nora
Published: March 2022

Gerald Taylor, el renombrado especialista en el Manuscrito Quechua de Huarochirí (MQH), tradujo el texto quechua empleando una escritura fonológica, pero un análisis gramatical o la descripción de sufijos excedía el propósito de su trabajo, por lo cual nos impusimos la tarea de analizar los sufijos.

Este artículo se basa en la investigación realizada en el Proyecto «Estudio de los sufijos del Manuscrito Quechua de Huarochirí (s. XVI)» en el cual hemos analizado los sufijos utilizados en el Manuscrito Quechua de Huarochirí (MQH), tanto los de los paradigmas nominal y verbal como los enclíticos. En el paradigma nominal, se ha descrito las características de los sufijos formativos, lo cual ayuda a conocer la verdadera raíz de palabras que terminan en -n y en -y, como hatun, wakin, uray; en el paradigma verbal se ha registrado la presencia de sufijos como -mpu y -tamu, que ya no se usan en las variedades modernas de quechua; también se ha establecido que en presencia de los sufijos -mu y -pu no se produce el cambio común de /u/ en /a/; así, tenemos en el MQH ruraykupuy, no ruraykapuy.
Breve evolución histórica de la discriminación lingüística en el Perú
Authors: Zamora Huamán Marco Antonio
Published: March 2022

La historia es un proceso de acontecimientos que forjan el devenir de una sociedad en su conjunto. La lengua, por su lado, no está exenta de tal exógena acometida, ya que, en el caso de la discriminación lingüística, es víctima de una serie de hechos sociales que han robustecido a lo largo de estos siglos el derrotero de la mayoría de lenguas amerindias del Perú, condenándolas a una agonía que hasta hoy persiste. El presente trabajo trata de dar una mirada oceánica a algunos de los hechos históricos que permitieron y siguen permitiendo que el fenómeno planteado continúe latente entre nosotros.
Conceptualización y partes del cuerpo en quechua en el s. XVII
Authors: Faucet Pareja Carlos Alberto
Published: March 2022

Este trabajo apunta a caracterizar tanto la manera en la que las partes del cuerpo eran conceptualizadas por los quechua hablantes de inicios del siglo XVII, como la conceptualización de las expresiones metafóricas/metonímicas en las que los nombres de las partes del cuerpo intervenían. El corpus analizado es de naturaleza textual y está conformado por el manuscrito de Huarochirí (1608) y las cartas de Cotahuasi (1616).
Sawkanakuy: aspectos cognitivos del humor en quechua
Authors: Ramos Tacca Mario
Published: March 2022

El presente estudio es una aproximación al conocimiento de los procesos cognitivos del humor en la lengua quechua. Se trata de un examen descriptivo de los actos comunicativos experienciales y corpóreos del lenguaje con énfasis en los factores gestálticos del comportamiento eufórico del hablante quechua. Por lo tanto, tiene el objetivo de analizar los esquemas cognitivos como procesos que construyen los significados contextuales en un corpus proveniente de discursos carnavalescos de las regiones de Apurímac, Cuzco y Puno.
Análisis semántico y hermenéutico de los términos chaka, chakana y chakata
Authors: Cisneros Ayala Claudia
Published: March 2022

Este artículo estudia la resemantización y determinación del significado de los términos quechua chaka, chakana y chakata. La investigación se centra en la explicación de la estructura morfológica. En el procedimiento partimos de la obra del Lexicón de 1560 donde hallamos el término chakata con significado de cruz. Para realizar el trabajo, se optó por el método filológico-hermenéutico y el uso de diccionarios quechuas. Como resultado del análisis, el término chakata tiene como lexema a chaka que indica el elemento de base que hace cruzar «X» elementos. Chakana sería el objeto con el que se hace cruzar los entes. Finalmente, la palabra chakata, aglutina al sufijo -ta con significado ‘inter’ o ‘entre’, siendo la palabra en conjunto chakatay ‘entrecruzar’. En conclusión, chakata significaría ‘entrecruc-’; en sentido filosófico, forma la base que entrecruza, «X» elementos dentro de la naturaleza y acciones humanas.
Análisis de la partícula japonesa ni en oraciones que expresan estados locativos
Authors: Rodríguez Bravo Andrea , Garay Ramírez Claudia Ximena
Published: March 2022

Este artículo trata sobre la variación de la partícula ni en oraciones que refieren estados locativos en la lengua japonesa. Se presenta los resultados del análisis de las partículas: wa, ga, y no; así como también la alternancia de uso de los verbos arimasu e imasu. El corpus del presente trabajo se divide en oraciones excesivas e inesivas, cada una con su respectiva formalización siguiendo la propuesta de Moreno Cabrera (2003). Finalmente, se demuestra lo postulado por Langacker (1987, como se citó en Moreno, 2003), quien postula que los adjetivos, adverbios y preposiciones determinan la relación de atemporalidad y, aunque el tiempo se presente no resulta relevante. De esta manera, se resalta el papel de la locatividad. En las oraciones analizadas, se demuestra que los adverbios determinan las oraciones locativas.
La representación de la mujer venezolana en redes sociales peruanas a través del término veneca
Authors: Prado Ishuiza Cesar Alberto , Zavala Coronel Sandra Gladys , Lovón Cueva Marco Antonio
Published: March 2022

En la actualidad latinoamericana, la migración venezolana se ha convertido en una problemática de índole política, económica, cultural y social. En ese sentido, en el territorio peruano, las olas migratorias han llevado a establecer medidas para atender a los venezolanos que huyen de la crisis en su país; por otra parte, las redes sociales han contribuido a formar una imagen estigmatizada del migrante. Este trabajo pretende analizar el discurso de los usuarios de las redes sociales respecto a la representación de la mujer venezolana a través del término peyorativo veneca. Metodológicamente, se recolectan comentarios en Facebook y Twitter durante el mes de junio de 2021. Finalmente, se concluye que la mujer venezolana es representada de forma negativa en base a las imágenes generalmente prejuiciosas que se les son atribuidas por los ciudadanos cibernautas peruanos.
EGFL7-blocking antibody inhibit pituitary adenoma proliferation and invasion
Authors: Liu Qian , Wang Jianpeng , Gao Hua , Zhang Yazhuo
Published: March 2022

Objective: To study the effect of EGFL7-blocking monoclonal antibody inhibiting the proliferation and invasion of mouse adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (ACTHomas) AtT-20 cells. Methods: After treated with different concentration of EGFL7-blocking monoclonal antibody for 24, 48, 72 h, the proliferation of AtT-20 cells was determined by MTS. Simultaneously, ACTH secretion of AtT-20 cells by ELISA and the mRNA expression of invasion related genes such as E-cadherin, snail, MMP-2 and MMP-9 by Real-time PCR were detected. Results: EGFL7-blocking monoclonal antibody could effectively inhibit the proliferation and ACTH secretion of AtT-20 cells in a dose-dependent and time-dependent manner. At the same time, EGFL7-blocking monoclonal antibody significant down-regulated the mRNA level of snail, MMP-2 and MMP-9 in AtT-20 cells. Conclusion: EGFL7-blocking monoclonal antibody could inhibit mouse pituitary adenoma AtT-20 cells proliferation and invasion.
Objectification of the stratification criteria in children with appendicular peritonitis for the selective hemoperfusion using the hemosorbent «Hemo-proteazsorb»
Authors:   Grodno State Medical University, Belarus, Vakulchik V. H. , Serhiyenka V. K. ,   Grodno State Medical University, Belarus
Published: March 2022

Peritonitis treatment in children remains one of the most complicated and urgent problem of modern surgery and intensive care. Particular attention is paid to therapy aimed to remove proinflammatory mediators and toxic substances. Hemoperfusion (HP) is a method based on elimination of toxic substances of an endogenous or exogenous nature from the patient’s blood by extracorporeal perfusion of whole blood through a special sorbent. However, to date, there are no clear clinical and laboratory criteria for the initiation, prolongation or completion of the HP procedure. Purpose – to objectify the stratification criteria in children with appendicular peritonitis for the selective HP using the hemosorbent «Hemo-proteazsorb». Materials and methods. The retrospective analysis of data from 60 patients with appendicular peritonitis was provided. Discriminant analysis was used. Results. Stratification criteria based on clinical and laboratory parameters of patients have been developed for HF procedure. Conclusions. The proposed scheme allows to stratify patients with appendicular peritonitis for the HP procedure. It makes possible to control the results of HP manipulation and allows to make decision whether to continue or complete treatment using the HP. Considering different capabilities of medical institutions, we recommend using the proposed method after validation of the results in these institutions. The study was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee. The informed consent of the parents for the research was obtained. No conflict of interest was declared by the authors. Key words: acute appendicitis, peritonitis, children, extracorporeal hemocorrection, hemoperfusion.
Predictors of frailty in older people users of Primary Health Care
Authors: Tavares João Paulo de Almeida , Sá-Couto Pedro Miguel Ferreira de , Pedreira Larissa Chaves
Published: March 2022

ABSTRACT Objective: to identify the prevalence and predictors of frailty in older people in Primary Health Care. Method: this is a descriptive and correlational study, carried out in a convenience sample of 136 older people in the community. Data were collected through a sociodemographic and clinical questionnaire and frailty phenotype. Student’s t test or U-Mann-Whitney test, chi-square and binary logistic regression were used for data analysis. Results: the prevalence of frailty was 26.5% (n=36). Frail individuals had older age (p=0.011), worse self-rated health (p=0.001) and lower physical capacity (p<0.001). In the multivariable regression, it was observed that frail individuals had older age (Odds Ratio=1.111; 95% confidence interval=1.026-1.203) and worse physical capacity (Odds Ratio=0.673; 95% confidence interval=0.508-0.893). Conclusions: the prevalence of frailty in older people in Primary Health Care was considerable. Advanced age and worse physical capacity were the most relevant predictors of frailty in the elderly.
Implications of Cannabis and Cannabinoid Use in COVID-19: Scoping Review
Authors: Pereira Caroline Figueira , Vargas Divane de , Toneloto Fernanda Lima , Ito Victor Daichi , Volpato Rosa Jacinto
Published: March 2022

ABSTRACT Objective: to identify and synthesize studies on the effects of cannabis use and its relation with SARS-CoV-2, as well as the therapeutic possibilities of using cannabinoids in the prevention and treatment of COVID-19. Methods: scoping review, in the BVS, PubMed, SCIELO, CINAHL, SCOPUS, Web of Science, MedNar, CAPES and ProQuest databases, with no language restriction and year limitation. Narrative synthesis was performed. Results: cannabis use causes changes in the respiratory and vascular system, it reduces the production of cytokines, which affects the users’ immune system, increasing the susceptibility to infection and progression of COVID-19. However, studies have suggested the use of cannabinoids in the prophylaxis and treatment of COVID-19, due to their anti-inflammatory effect. Conclusions: the use of inhaled cannabis increases the progression and severity of the infection. On the other hand, the benefits of cannabinoids seem promising to modulate the immune system, but it needs further studies.
Woman-centered shared decision-making to promote contraceptive counseling: an integrative review
Authors: Silva Roger Rodrigues da , Silva Filho José Adelmo da , Lima Edilson Rodrigues de , Belém Jameson Moreira , Pereira Rafael da Silva , Oliveira Camila Almeida Neves de
Published: March 2022

ABSTRACT Objective: To summarize scientific evidence on the woman-centered shared decision-making process for the promotion of contraceptive counseling. Methods: Integrative literature review with a sample of nine primary articles selected from MEDLINE via PubMed, CINAHL, Web of Science, Scopus, ScienceDirect, Embase, LILACS, and BDENF. Results: The study evidenced a comprehensive chain of segments for the development of the shared approach centered on women through counseling on contraception, fragmenting the evidence acquisition in relational elements for the choice implementation and continuation of the chosen method; systematization of consistent information for choice implementation and continuation of the method; and challenges for implementing shared decision-making. Final considerations: The process of woman shared decision-making centered during the consultation on contraception counseling favors the qualified choice and effective adherence to a contraceptive method based on the professional’s clinical vision adjusted to the woman’s preferences.
Gender violence perpetrated against trans women
Authors: Silva Izabel Cristina Brito da , Araújo Ednaldo Cavalcante de , Santana Alef Diogo da Silva , Moura Jefferson Wildes da Silva , Ramalho Marclineide Nóbrega de Andrade , Abreu Paula Daniella de
Published: March 2022

ABSTRACT Objectives: to identify scientific evidence on gender violence perpetrated against trans women. Methods: integrative review, carried out in June 2020, without time frame, in the Scopus, MEDLINE, Embase, CINAHL, WoS, PsycInfo and LILACS databases. The controlled descriptors of DeCS, MeSH and their entry terms were used: “Transgender People”, “Transgender”, “Gender Identity”, “Transsexuality”, “Gender Violence”, “Aggression”, “Sexual Offenses”, “Rape”, “Violence”, “Domestic Violence”. The presentation and synthesis of the results were presented in the PRISMA-2009 flowchart. Results: the final sample, consisting of 16 articles, identified different types of violence (sexual, physical, verbal, psychological and financial), perpetrated by family members, strangers, police officers, intimate partners, health professionals, acquaintances, or friends. Conclusions: trans women suffer violence and social exclusion that result from stigma and discrimination due to gender identity and result in unrestricted damage to physical health.
Transitional rehabilitation care and patient care continuity as an advanced nursing practice
Authors: Pedrosa Ana Rita Cardoso , Ferreira Óscar Ramos , Baixinho Cristina Rosa Soares Lavareda
Published: March 2022

ABSTRACT Objective: To analyze the needs and facilitating and hindering elements related to transitional rehabilitation care. Methods: Integrative literature review oriented toward answering the question “What nursing interventions guarantee transitional rehabilitation care to dependent adult or elderly people when they return home after hospitalization?”. Results: The patients did not participate much in the planning of hospital discharge and decision-making when they had to return home. Informal caretakers reported that professionals showed detachment during hospitalization and delayed guiding instructions. Health professionals mentioned lack of time to offer this care modality as a difficulty. Final considerations: Ensuring training, follow-up, and coordination between care levels is essential. Care integration can reduce hospital stay and the impact of post-discharge complications. Transitional care contributes to a sustainable health system, higher care quality, and client satisfaction.
Adaptation and validation of the Advanced Practice Nursing Competency Assessment Instrument
Authors: Dias Flávia Carvalho Pena , Baitelo Tamara Cristina , Toso Beatriz Rosana Gonçalves de Oliveira , Sastre-Fullana Pedro , Oliveira-Kumakura Ana Railka de Souza , Gasparino Renata Cristina
Published: March 2022

ABSTRACT Objective: To adapt and validate the content of the Advanced Practice Nursing Competency Assessment Instrument (APNCAI) to Brazilian culture. Methods: This is a methodological study that followed the stages of translation, synthesis, back translation, evaluation by a committee of five specialists, pre-test with 31 nurses, and evaluation by the author of the original instrument. The Content Validity Index (minimum 0.90) and the modified Kappa (minimum 0.74) were calculated to evaluate the content. Result: In the first round of content evaluation, 18 items had to be altered because they did not reach the minimum values established. Three items have not reached a consensus in the second round and had to be sent to the author of the original version. In the pre-test, 13 items were returned to the specialists because they suffered content changes. Conclusion: The Advanced Practice Nursing Competency Assessment Instrument (APNCAI) - Brazilian version was cross-culturally adapted, and its content was validated.
Subcutaneous tissue reaction and gene expression of inflammatory markers after Biodentine and MTA implantation
Authors: Silva Raquel Assed Bezerra , Gaton-Hernandez Patrícia , Pucinelli Carolina Maschietto , Silva Francisco Wanderley Garcia de Paula e , Lucisano Marília Pacífico , Consolaro Alberto , Sá Rafaela Cardoso de , Araujo Lisa Danielly Curcino , Sousa-Neto Manoel Damião , Silva Léa Assed Bezerra
Published: March 2022

Abstract The aim of this study was to evaluate the subcutaneous connective tissue response of isogenic mice exposed to tricalcium silicate (Biodentine) and aggregated mineral trioxide (ProRoot MTA). A total of 120 mice were divided into 4 groups in 3 different experimental periods (7, 21 and 63 days): Biodentine; Pro-Root MTA; zinc oxide-eugenol and; Negative control - Sham. After the experimental periods microscopic descriptive, semi-quantitative and quantitative analysis of the inflammatory process were analyzed on H&E sections and evaluation of the gene expression of Il10, Infg, Il6, Il1r1 and Tnf (qRT-PCR) were performed. The data obtained were analyzed using the chi-square test and two-way analysis of variance (ANOVA) followed by the Bonferroni post-test (5% significance level). Results: In the microscopic analysis, a slight inflammatory infiltrate was observed, with a predominance of sparse macrophages and polymorphonuclear cells, slight tissue fibrosis, regular fibrous capsule and with dystrophic calcifications, in all groups that received the materials (Biodentine and Pro-Root MTA). In parallel, all materials modulated the gene expression of the different cytokines and receptors evaluated. Conclusion: Pro-Root MTA and Biodentine showed a tissue compatibility, mediated inflammation, with increased fibrous tissue and production of pro- and anti-inflammatory cytokines.
Validation of the brazilian version of the oral health impact profile - Aesthetic questionnaire
Authors: Hanan Simone Assayag , Cohen-Carneiro Flávia , Herkrath Fernando José , Oliveira Branca Heloisa de , Loguércio Alessandro Dourado , Martins Leandro de Moura , Herkrath Ana Paula Corrêa de Queiroz
Published: March 2022

Abstract The aim of the study was to develop the Brazilian version of the Oral Health Impact Profile - Aesthetic Questionnaire (OHIP-Aes-Braz) and test its psychometric properties. The questionnaire test versions were developed by a panel of experts and a pre-test was conducted in a focus group. Data used for testing its psychometric properties were obtained from a randomized controlled clinical trial on tooth bleaching. Seventy-nine Brazilian adults were included. The questionnaires were applied before tooth bleaching treatment (baseline), one week (T1), and one month after the intervention (T2). Reliability was assessed in terms of internal consistency and stability, while validity was ascertained by criterion and construct validity. The sensitivity to change was assessed comparing the total scores at baseline and T2, using the Wilcoxon test (α = 0.05). Both stability and internal consistency (intra-class correlation coefficient=0.95, Cronbach’s α = 0.92) proved to be adequate. Construct validity was confirmed as the correlation between OHIP-Aes-Braz scores with tooth color satisfaction and self-perceived oral health were in the expected direction. A positive correlation between OHIP-Aes-Braz and OHIP-14 (rs=0.63) and OIDP (rs=0.77) was observed. The instrument was responsive once differences in total scores before and after treatment were statistically significant (p<0.001). The OHIP-Aes-Braz presented good psychometric properties and showed sensitivity to change regarding aesthetics evaluation in Brazilian adults treated with tooth bleaching. A valid and reliable instrument allows a suitable assessment of oral health-related quality of life in Brazilian patients submitted to aesthetics dental interventions.
Management of periapical lesion with persistent exsudate
Authors: Quaresma Sérgio André , Costa Rui Pereira da , Batalha Beatriz , Quaresma Maria Carlos Real Dias , Lopes Fabiane Carneiro , Mazzi-Chaves Jardel Francisco , Ginjeira Antônio , Sousa-Neto Manoel Damião de
Published: March 2022

Resumo Este relato de caso descreve o tratamento e acompanhamento de um molar inferior em uma jovem de 18 anos com cisto periapical. Assim, torna-se importante saber quais opções devemos tomar diante de uma situação clínica que não podemos resolver pelos métodos convencionais, e quais técnicas e abordagens temos para alcançar o sucesso do tratamento. Este caso mostrou o plano de tratamento e acompanhamento, por meio de imagens de tomografia computadorizada de feixe cônico (TCFC), de um molar inferior previamente tratado com grande abscesso periapical e lesão cística, no qual, a primeira abordagem do plano de tratamento foi fazer o retratamento endodôntico. Durante o preparo químico-mecânico a presença de exsudato purulento intracanal permanente impossibilitou a secagem dos canais, impedindo a obturação do sistema de canais radiculares. Devido a essa situação clínica, foi realizada abordagem cirúrgica com a intenção de reduzir esse exsudato permanente e executar uma técnica de descompressão. Após um ano de acompanhamento, os achados clínicos e radiográficos indicaram processo de reparo.
Agrobiological evaluations of newly introduced grapes varieties under climatic conditions of the south of Kazakhstan
Authors: Chupradit S. , Huy D. T. N. , Hachem K. , Shichiyakh R. A. , Bokov D. , Mahmudiono T. , Al-Rekaby H. Q. , Kadhim M. M. , Thangavelu L.
Published: March 2022

Abstract Variety assortment enhancement is a normal task that involves enhancing the assortment's quality and upgrading varieties. The findings of a research of imported grape varieties in the southeast of Kazakhstan, namely in the Almaty region's bottom-mountain zone, are presented in this article. The onset and conclusion of the main phenological phases of a grape plant throughout the vegetative period were directly influenced by the climatic and meteorological conditions of this district. In comparison to the recognized variety Almaty early-maturing, it has been proven that types Priusadebny, Iyulsky, and Kuibyshevsk early-maturing have a high degree of eyes wintering buds and may provide a high-quality crop in this location.