bluuebunny/crossref_metadata_2025 huggingface dataset:
Developing a predictive nomogram and web-based survival calculator for locally advanced hypopharyngeal cancer: A propensity score-adjusted, population-based study
Authors: Chen Sihao , He Shanshan , Wang Dan , Liu Yi , Shao Shilong , Tang Li , Li Chao , Shi Qiuling , Liu Jifeng , Wang Feng , Zhan Shichuan
Published: April 2023

Understanding the clinical features and accurately predicting the prognosis of patients with locally advanced hypopharyngeal squamous cell carcinoma (LA-HPSCC) is important for patient centered decision-making. This study aimed to create a multi-factor nomogram predictive model and a web-based calculator to predict post-therapy survival for patients with LA-HPSCC. A retrospective cohort study analyzing Surveillance, Epidemiology, and End Results (SEER) database from 2004 to 2015 for patients diagnosed with LA-HPSCC was conducted and randomly divided into a training and a validation group (7:3 ratio). The external validation cohort included 276 patients from Sichuan Cancer Hospital, China. The Least Absolute Shrinkage and Selection Operator (LASSO)-Cox regression analysis was used to identify independent factors associated with overall survival (OS) and cancer-specific survival (CSS), and nomogram models and web-based survival calculators were constructed. Propensity score matching (PSM) was used to compare survival with different treatment options. A total of 2526 patients were included in the prognostic model. The median OS and CSS for the entire cohort were 20 (18.6-21.3) months and 24 (21.7-26.2) months, respectively. Nomogram models integrating the seven factors demonstrated high predictive accuracy for 3-year and 5-year survival. PSM found that patients who received surgery-based curative therapy had better OS and CSS than those who received radiotherapy-based treatment (median survival times: 33 months vs 18 months and 40 months vs 22 months, respectively). The nomogram model accurately predicted patient survival from LA-HPSCC. Surgery with adjuvant therapy yielded significantly better survival than definitive radiotherapy. and should be prioritized over definitive radiotherapy.
Geographic Information Systems (GIS)-based spatial analysis of cell distribution v1
Authors: Merighi Adalberto
Published: April 2023

This protocol describes how to perform a Geographic Information Systems (GIS)-based spatial analysis of cerebellar images. It can be used for any biological images to study cellular or molecular spatial distributions, or, more generally, the distribution of any biological feature of interest. The procedures described here can be employed singularly or in combination to analyze clustering/dispersion by GIS spatially. It is based on the use of ESRI ArcMap to calculate the Average Nearest Neighbor, the High/Low Clustering (G tool), the Multi-distance Spatial Cluster Analysis (Ripley’s K Function), and the Spatial Autocorrelation (Global Moran’s I). It is also shown how to represent the features' distribution graphically.
DNA Quality Control by Agarose Gel Electrophoresis v1
Authors: Schwessinger Benjamin
Published: April 2023

This protocols is part of the ANU Biosecurity mini-research project #1 "Plant Pathogen Diagnostics: Visuals, subcultures, and genomics". You will be provided four pots of 3-4 week old wheat plants that have been infected with different wheat pathogens. Each pot has been infected with one major pathogen. You will not know which pot has been infected with which pathogen. However, you will be provided a compendium of 10-15 wheat pathogens that will guide you to identify the infective agent for each treatment group. The fifth treatment group will be uninfected wheat plants which will be clearly identified. You can use treatment group #5 as negative control for your experiments. In total, each group will obtain five pots each: This specific protocol is a step by step guide to assess DNA quality via agarose gel electrophoresis. Agarose gel electrophoresis lets you assess the size of DNA molecules. In addition, you can estimate DNA concentrations and impurities of RNA. During agarose gel electrophoresis DNA gets linearised. Larger molecules take longer to migrate through the gel when migration is driven by a electric potential at the specific pH of the buffer. When running a standard DNA ladder with bands of known molecular size, one can compare the DNA size of ones DNA or PCR sample with the known standards. The final goal is to achieve the following: To assess DNA length of molecules in DNA stock samples and for all PCR reactions. To approximately estimate relative DNA concentrations. To test if negative PCR controls did not amplify anything as appropriate. To test if whole DNA extracts contain RNA in addition to DNA. This protocol is applicable for week 5. Protocols progress overview: Week 5 Run a 1% Agarose Gel electrophoresis for all samples of each research group. Some useful explainers and resources: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846332/ https://en.wikipedia.org/wiki/Agarose_gel_electrophoresis https://www.youtube.com/watch?v=ZDZUAleWX78
Carcass yield, non-carcass components and economic viability of using licuri oil in the diet for Santa Inês ewe’s
Authors: Lima-Cavalcanti Cinthia P , Silva-Macedo Taís J , Costa-Gois Glayciane , Gonçalves-Menezes Vanúzia , Oliveira-Monte Alane P , Domingos-Silva Alex , Menezes-Silva Dielen J , Nunes-Nascimento Paulo V , Oliveira-Silva Elves , Leal-Araújo Gherman G , Souza-Rodrigues Rafael T , Wischral Áurea , Tavares-Matos Maria H , Ávila-Queiroz Mário A
Published: April 2023

Background: The production of biofuels has caused an increase in the prices of agricultural commodities. Thus, the ecological footprint, social inclusion and profitability of production systems have encouraged the use of agroindustrial products as an alternative in ruminant feeds. Objective: To evaluate carcass yields, non-carcass components, and the economic viability of including licuri oil in diet of Santa Ines ewes. Methods: A total of 32 Santa Ines ewes (multiparous, non-lactating, 2–4 years old, and 36.7±0.87 kg of body weight—BW) were allotted to a randomized block design with four treatments (diets containing 0, 2, 4 or 5% licuri oil) with eight replicates per treatment, and confined for 77 days. Results: The incremental inclusion of licuri oil promoted a quadratic response on slaughter BW, carcass and true yields, chest widths, heart fat, pancreas, omental fat, and ribeye area (p<0.05). Carcass, heart and loin weight, shank yield, fat thickness and loin fat were reduced (p<0.05); while cooling losses, left half-carcass weight, saw blade yield, and proportion of meat in the loin increased (p<0.05) with increasing dietary levels of licuri oil. The control diet resulted in the best gross revenue (USD$609.39); however, there was a loss (USD$50.96) regarding economic performance indicators. Conclusion: The use of up to 2% licuri oil in the diet increased carcass yield of discard ewes.
The Effect of Entrepreneurial Orientation and Dynamic Capability on Business Performance in Creative Industry: Mediating Role of Innovativeness Product Advantage
Authors:   People&Global Business Association, Hikmah Hikmah , Ratnawati Andalan Tri , Darmanto Susetyo
Published: April 2023

Purpose: This study aims to analyze the effect of entrepreneurial orientation and dynamic capabilities on the innovativeness product advantage, the influence of entrepreneurial orientation and dynamic capabilities on the business performance of the creative industry, and the effect of innovativeness product advantage on the business performance of creative industries. This study also examines the mediating role of innovativeness product advantage in mediating entrepreneurial orientation and dynamic capabilities on creative industry business performance.
Design/methodology/approach: The population is creative industry entrepreneurs in the Semarang city. Sample selection was done by purposive sampling method, obtained 150 data were declared eligible for analysis. Data analysis using SEM with IBM SPSS Amos 26.0,0 software tools.
Findings: The research result showed that the entrepreneurial orientation and dynamic capability have a significant effect on the innovative product advantage and business performance. Another finding indicated that the innovativeness product advantage had an mediating role on the influence of entrepreneurial orientation and dynamic capability toward business performance.
Research limitation/implications: Despite following scientific principles, the sample limitation is a limitation of this research. Therefore, further research is expected to expand the scope of the research object to obtain more comprehensive results. To generalize the results, future research should include other antecedents, such as intellectual capital and networking.
Originality/value: This research contributes to the development of resource-based theory by providing a better understanding of creative business development models. Furthermore, this research proposes the innovativeness product advantage so that the creative industry can compete in the digital era.
Features of subcutaneous cardioverter-defibrillators implantation
Authors: Amiraslanov Anar Yu. , Artyukhina Elena A. , Revishvili Amiran Sh.
Published: April 2023

According to global statistics, 25% of deaths every year are cases of sudden cardiac death. Implantation of cardioverter-defibrillators is currently used as its prevention. In the coming years, the world is projected to see an increase in the number of implantations of cardioverter-defibrillators in high-income countries, as well as an expansion of the range of medical devices offered, including subcutaneous cardioverter-defibrillators, which are currently being considered as a promising alternative. We systematized the literature data presented in various international studies evaluating the efficacy and safety of the use of subcutaneous cardioverter-defibrillators. Areview of the medical literature published in the period from 2015 to 2022 was carried out using the information and analytical systems MEDLINE, Scopus, Clinicaltrials.gov, Google Scholar and Web of Science. The review was performed in accordance with the checklist of preferred reporting items for systematic reviews and meta-analyses. 398original publications were selected, of which 50original scientific articles on the research topic were included in the analysis. Modern international studies have demonstrated the efficacy and safety of the use of subcutaneous implantable cardioverter defibrillators. An improvement in the performance of unmotivated discharges over time was noted, which was associated with the improvement of implantable cardioverter-defibrillators. The operating time for implantation of subcutaneous cardioverter-defibrillators was significantly less compared to transvenous cardioverter-defibrillators. Subcutaneous cardioverter-defibrillators were associated with a lower incidence of perioperative complications and high efficacy of shock therapy. Subcutaneous cardioverter-defibrillators were as effective as transvenous implantable cardioverter-defibrillators and did not have the risk of complications associated with implantation of endocardial electrodes. The main limitations of the technique were the impossibility of pacing and the absence of antitachycardic stimulation.
Anemia of chronic diseases: a verdict or a protective reaction of the body?
Authors: Valitova Azaliya D. , Kadyrova Zulfinaz M. , Oslopov Vladimir N. , Oslopova Yulia V. , Khazova Elena V.
Published: April 2023

Anemia of chronic disease occurs in patients with infectious, autoimmune, kidney diseases, neoplasia, inflammatory bowel disease, obesity, diabetes mellitus, congestive heart failure, and chronic lung disease. This variant of anemia is characterized primarily by impaired iron homeostasis, the suppressive effect of pro-inflammatory cytokines on erythropoiesis, and changes in the erythrocyte membrane that worsen their survival. Anemia of chronic disease is micro- or normocytic anemia with low levels of reticulocytes. In anemia of chronic disease, serum iron and transferrin levels are usually reduced or normal, and serum ferritin levels are within reference values or elevated. The article provides a review of studies on epidemiology, including age aspects, provides information on the etiology and prognosis in patients with anemia of chronic diseases. The issues of the history of anemia of chronic diseases and its place in the structure of all anemias are also covered. Anemia of inflammation is recognized as a widespread pathology; it occupies 40% in the structure of all anemias. It is important to note that anemia of chronic diseases, while accompanying a number of dangerous diseases, actually serves as a natural defense mechanism. This is due to the occurrence of iron starvation for microorganisms, since inflammatory reactions increase the synthesis of iron proteins, which quickly extract extracellular and unbound iron. This mechanism allows a person to destroy the infection in time with the help of innate immunity. The article reveals the pathogenetic aspects of anemia of inflammation development and data on the role of iron in the functioning of macro- and microorganisms. Particular attention is paid to the differential diagnosis of anemia of chronic diseases and iron deficiency anemia, key diagnostic hematological markers of anemia, iron metabolism, inflammation and erythropoiesis are given. The pros and cons of therapy options, as well as possible new pathogenetic methods for the treatment of anemia of chronic diseases, are described.
The course of chronic heart failure in patients after COVID-19 against the background of active cytomegalovirus infection
Authors: Shilov Sergey N. , Mayanskaya Svetlana D. , Pankova Irina V. , Grigoreva Natalya S. , Govor Inna V.
Published: April 2023

Background. A new coronavirus infection may be complicated in the post-COVID period by the development of adverse cardiovascular events associated with chronic heart failure.
Aim. To study the features of the course of chronic heart failure in patients after COVID-19 infection against the background of active cytomegalovirus infection.
Material and methods. The study included 102 patients with chronic heart failure with reduced and intermediate left ventricular ejection fractions, who underwent COVID-19 in mild and moderate forms. The control group consisted of 61 patients with chronic heart failure and no COVID-19. Within 6 months after the infection with COVID-19, the features of the course of chronic heart failure were assessed. Quantitative determination of deoxyribonucleic acid (DNA) of cytomegalovirus in blood plasma was carried out by polymerase chain reaction. To assess the risk of adverse events, the odds ratio (OR) with a 95% confidence interval (95% CI) was calculated. Quantitative data were presented as median and interquartile range (25th and 75th percentiles).
Results. After coronavirus infection, the risk of an unfavorable course of chronic heart failure (OR=6.237; 95% CI=2.91113.362; p=0.001), hospitalization due to decompensation of chronic heart failure (OR=5.9; 95% CI=1.31326.504; p=0.033), an increase in the functional class of heart failure by 1 class or more (OR=4.19; 95% CI=1.63610.736; p=0.009), development of atrial fibrillation paroxysms (OR=3.832; 95% CI=1.38510.599, p=0.014), significantly increased. The number of copies of cytomegalovirus DNA in patients who underwent COVID-19 was significantly higher in the group of patients with an unfavorable course of chronic heart failure compared to the same group, in which patients did not tolerate COVID-19 2238.5 (1888.5; 2647.5) and 1411.5 (1112.5; 1684.5) copies/ml, respectively (p 0.001).
Conclusion. Patients with chronic heart failure after 6 months of COVID-19 infection are at high risk of developing adverse cardiovascular events against the background of active cytomegalovirus infection.
Research of breeding sites capacity for
oviposition of floodwater mosquitoes in flooded area of Danube and Drava rivers
in Croatia
Authors: Davidović Ramona-Ana , Lalić Deborah , Pavičić Anamaria , Garcia Javier Nevado , Merdić Enrih
Published: April 2023

Floodwater mosquitoes lay their eggs on dry ground where water will eventuallyflood the area. By flooding the area and submerging the eggs of floodwater mosquitoes, the development of larvae begins. For a gravid female mosquito, the mostimportant thing is choosing the place where to lay eggs. As part of this research,which was conducted in April and May 2022, soil and leaf samples were taken on anarea of 50 x 50 cm from different altitudes in the area of Dunavac near Ilok (Danube)and Halaševo near Osijek (Drava) in order to determine at which altitude, the largestnumber of eggs are laid. Collected soil was submerged in the laboratory for the purpose of further mosquito development. Part of the larvae was preserved in alcohol,and part of larvae was left to develop into adults, after which species determinationwas carried out. A large difference was found in the potential of breeding sites in thefloodplain of the Drava and Danube, and the number of collected eggs ranged from0 to 66 per sample. The number of individuals sampled in the Danube area was 53,and in the Drava area 133. The individuals sampled in the researched areas weredetermined as Aedes vexans and Aedes sticticus. A large difference in oviposition wasfound in the floodplain of the Danube, while in the floodplain of the Drava, this levelis significantly higher.
Nove vrste iz porodice Psyllidae
(Hemiptera: Sternorrhyncha: Psylloidea) zabilježene u Hrvatskoj
Authors: Pintar Maja , Šimala Mladen
Published: April 2023

Lisne buhe (Hemiptera: Sternorrhyncha: Psylloidea) sitni su kukci koje je u prirodi teško otkriti, posebno kada se nalaze u populacijama niskog intenziteta. Procjenjuje se da je u svijetu do danas opisano oko 4000 vrsta klasificiranih u sedam porodica. Samo manji broj vrsta ubraja se u važne poljoprivredne štetnike, a u posljednje vrijeme dobivaju na značaju zahvaljujući spoznaji da prenose uzročnike biljnih bolesti. Faunističko istraživanje lisnih buha u Hrvatskoj započelo je 2015. godine. Cilj ovog istraživanja bio je sastaviti popis vrsta lisnih buha prisutnih u Hrvatskoj, uz pregled pripadajućih biljaka domaćina, kao i utvrditi potencijalno prisustvo nekih do danas u Hrvatskoj nepoznatih vrsta. Odrasli primjerci lisnih buha uzorkovani su entomološkim kečerom ili metodom otresanja biljaka na bijelu podlogu te su usnim aspiratorom prikupljani u Falcon epruvete i do laboratorijske analize pohranjeni u 70% etilni alkohol. Identifikacija vrsta provedena je klasičnom makroskopskom i mikroskopskom analizom na osnovi morfoloških karakteristika odraslih stadija i genitalija mužjaka, vrlo rijetko i ženki, uz korištenje dihotomnih ključeva dostupnih u literaturi. U periodu od 2015. do 2021. godine sljedeće vrste lisnih buha iz porodice Psyllidae zabilježene su po prvi puta u Hrvatskoj: Diaphorina chobauti Puton, 1898, Arytaina genistae (Latreille, 1805), Cacopsylla brunneipennis (Edwards, 1896), Cacopsylla myrthi (Puton, 1876), Cacopsylla saliceti (Foerster, 1848), Livilla variegata (Löw, 1881), Psylla foersteri Flor, 1861 i Psylla hartigii Flor, 1861.
Quality of Life and Pain Syndrome in Patients With Thoracic Aorta Repair Using a Mini-Sternotomy
Authors: Charchyan E. R. , Breshenkov D. G. , Neizvestnykh D. P. , Chakal D. A. , Belov Yu. V.
Published: April 2023

Aim      To determine the effect of minimally invasive interventions on the quality of life (QoL), pain syndrome, and cosmetic effect in patients with a pathology of chest aorta as compared with a group of traditional access.

Material and methods  From 2016 through 2020, 77 of 226 (34%) patients with an aneurysm in the proximal chest aorta and mini-sternotomy were prospectively selected starting from 2017. To evaluate differences between the effects of mini-sternotomy and the traditional access on QoL and pain syndrome a control group of patients with full sternotomy (n=77) was formed using pseudorandomization. Intergroup comparison of QoL, pain syndrome, and cosmetic parameters was performed at various time points.

Results Mini-sternotomy provided a decrease in pain syndrome both during the early period (day 3), and during movements upon discharge. Also, mini-sternotomy decreased the duration of stay in the hospital compared to full sternotomy (8.1±2.1 vs. 8.9±2.5 days, respectively; р>0.0331). A more frequent use of analgesics by patients with full sternotomy was noted. Mini-sternotomy was associated with a faster recovery of most QoL parameters according to the SF-36 questionnaire at one year after surgery. The questionnaire included summarizing parameters of physical and mental health components (Physical Health Component, Physical Health (PH): 54.3±11.9 vs. 58.2±8.2, respectively; p=0.046; Mental Health Component, Mental Health (MH): 53.8±6.8 vs. 57.8±9.5, respectively; p=0.013). In addition, patients with minimal access showed higher values of the cosmetic effect by a 5-score scale (4.08±0.8 vs. 4.39±0.8, respectively; p=0.049) and a greater interest to having a minimal access surgery.

Conclusion      Mini-sternotomy beneficially influences the pain syndrome, cosmetic outcome, and QoL and provides a shorter duration of rehabilitation and a sooner return to work and everyday life compared to full sternotomy.
Efficacy and Safety of Nonfluoroscopic Approach During Catheter Ablation of Ventricular Tachycardias
Authors: Huseynli E. G. , Sapelnikov O. V. , Amanatova V. A. , Ardus D. F. , Khachirov M. R. , Grishin I. R. , Cherkashin D. I. , Saidova M. A. , Stukalova O. V. , Shlevkov N. B. , Uskach T. M. , Akchurin R. S.
Published: April 2023

Aim      To evaluate a possibility of using radiofrequency catheter ablation guided by intracardiac echocardiography (ICE), its efficacy and safety for treatment of ventricular tachycardia (VT) of various etiology.

Material and methods  Catheter intervention was performed for 20 enrolled patients with symptomatic VT. Ablation procedures were guided by a 3D electroanatomical mapping system and ICE.

Results Mean duration of the procedure was 201.2±62.5 min. The procedure was successful (non-inducibility of VT) in 100% of cases. None of the patients had postoperative complications.

Conclusion      Ablation of VT arrhythmogenic substrate guided by 3D electroanatomical navigational mapping and ICE without X-ray is feasible and safe.
Research Insights: What Can Multilateral Development Banks Do to Reduce Infrastructure Gaps in Emerging Economies?
Authors: Avellán Leopoldo , Galindo Arturo , Lotti Giulia , Rodríguez Bonilla Juan Pablo
Published: April 2023

Through their loans, Multilateral Development Banks (MDBs) are key resource mobilizers. MDB lending to a sector in a country significantly increases inflows from other sources up to two years later. The resources mobilized are more than four times the size of MDB financing. They come from both the public and the private sector, and the mobilization that takes place is cross-border as well as national.
Research Insights: What Are the Effects of Weather-Induced Rural-Urban Migration on Destinations’ Labor and Housing Markets?
Authors: Busso Matías
Published: April 2023

Cities that received more migrants observed faster growth in employment and a slower increase in wages. The wage effects are stronger in the service sector, likely due to its higher degree of labor informality. The stock of precarious housing units increased in cities receiving more rural migrants, rents for this type of housing did not increase, suggesting that supply kept pace with migration-driven growth in demand. Non-precarious housing experienced faster growth in rents but slower growth in quantities in cities that received more rural migrants. This is consistent with cities having a limited supply of land for housing.
Nurses' knowledge in nursing care and treatment of burns
Authors: Qtait Mohammad
Published: April 2023

Burn is one of the most painful and costly injuries to get. Burn patients need the nurse's help more than anyone else to improve. This study aims to determine how much hospital nurses know about burns, burn treatments, nursing care for burns, and their effects. The study had a quantitative descriptive design, conducted at government and non-government hospitals in the south of the West Bank, with 223 nurses. The results revealed that most nurses have inadequate knowledge of burn care, moderate knowledge of burn nurse treatment knowledge for complications, adequate knowledge of renal failure, sepsis, and shock, and adequate knowledge of deep vein thrombosis and pulmonary edema. The nurses' expertise in burn treatment and nursing was average, and their understanding of burn therapy and related hospital-based problems was also intermediate.
Keywords: Burn; burn treatment; care; nurse knowledge.
Acute Ischemic Stroke Management: A Systematic Review
Authors: Li Xiang
Published: April 2023

With the increasing improvement of living standards, stroke also has a very high incidence rate in the world, in which ischemic stroke accounts for 60%-80% [1]. But many people, even medical students, know very little about stroke treatment. Therefore, I intend to write a review of the treatment of Acute Ischemic Stroke (AIS), which will give the reading public a systematic understanding of the treatment of acute ischemic stroke, reduce the public’s fear of stroke, and make patients and their families trust doctors. This article focuses on the treatment options for mild ischemic stroke and heavy ischemic stroke. The treatment options for mild ischemic stroke are thrombolytic therapy or short-term dual antiplatelet therapy [2]; the treatment options for heavy ischemic stroke are bridging therapy or direct endovascular intervention.
Wolności szlacheckie w Rzeczypospolitej Obojga Narodów
Authors: Naworski Zbigniew
Published: April 2023

Celem opracowania jest charakterystyka części składowych wolności szlacheckiej z perspektywy okresu Rzeczypospolitej szlacheckiej oraz czasów współczesnych. Autor wskazuje, że dotychczas w zasadzie brak dokładnego zdefiniowania zakresu tej wolności. Z reguły określa się ją owym zbiorczym terminem „wolność szlachecka”, choć należałoby używać raczej liczby mnogiej „wolności szlacheckie”. W artykule autor wnikliwie analizuje wolności polityczne, wolność sumienia i wyznania, wolność słowa i opinii, wolności osobiste oraz wolności prawa ekonomiczne, socjalne i kulturalne szlachty. Ustala także, czy wolności te w sensie prawnym obejmowały cały stan szlachecki, czy tylko jego część. Szczegółowe rozważania rodzajów tych wolności zostały poprzedzone analizą statusu prawnego stanu szlacheckiego.
Odwiedzenie od wiary według Kodeksu Kar Głównych i Poprawczych z 1847 r.
Authors: Koredczuk Józef
Published: April 2023

Przestępstwa przeciwko religii w Kodeksie Kar Głównych i Poprawczych uznano za bardzo ważne, zaliczając je do przestępstw dotyczących bezpośrednio Rządu. Religię w Kodeksie uznano za główną podstawę porządku i pomyślności społeczeństw. Dlatego twórcy Kodeksu uznali za konieczne przeciwstawić się zamachom dążącym do zachwiania wiary chrześcijańskiej, a szczególnie prawosławnej. Jednym z takich zamachów godzących w fundamenty religijne państwa było odstąpienie od wiary, czyli apostazja. Szczególnej ochronie na podstawie Kodeksu podlegała religia prawosławna jako religia panująca nie tylko w Rosji, ale również w Królestwie Polskim. Przepisy Kodeksu obowiązujące w Królestwie z jednej strony chroniły Kościół katolicki przed zamachami na niego, z drugiej zaś strony były formą represji w imię ochrony uprzywilejowanej pozycji Kościoła prawosławnego.
Przykłady ograniczenia wolności słowa na podstawie polskiego kodeksu karnego z 1932 roku w świetle doktryny oraz orzecznictwa z okresu międzywojennego
Authors: Pasek Andrzej
Published: April 2023

Artykuł analizuje stany faktyczne przestępstw ujętych w polskim kodeksie karnym z 1932 r. ograniczających prawo do swobodnego wyrażania swoich myśli i przekonań. Wykazano, że zakres ochrony dóbr prawnych kolidujących z wolnością słowa był twórczo kształtowany przez doktrynę prawa i judykaturę. Pod tym kątem omówione zostały kolejno: osłabianie ducha obronnego społeczeństwa w czasie wojny lub w okresie grożącej wojny (art. 104), rozpowszechnianie za granicą nieprawdziwych wiadomości w celu szkodzenia interesom Państwa Polskiego (art. 109), nawoływanie do wojny zaczepnej (art. 113), znieważanie władzy, urzędu, wojska lub marynarki wojennej (art. 127), lżenie lub wyszydzanie Narodu albo Państwa Polskiego oraz nawoływanie do popełnienia przestępstwa (art. 154). Analiza tych stanów faktycznych potwierdziła, że prawo do swobodnego wyrażania swoich myśli i przekonań nie miało nieograniczonego charakteru. Korzystanie z niego nie mogło bowiem skutkować wyczerpaniem ustawowych znamion przestępstw ujętych w cytowanych w opracowaniu artykułach kodeksu karnego pod rygorem zastosowania przewidzianych w nich surowych sankcji.
Rapid Diagnosis of Recurrent Paucibacillary Tuberculosis
Authors: Jafari Claudia , Olaru Ioana Diana , Daduna Franziska , Lange Christoph , Kalsdorf Barbara
Published: April 2023

Introduction: The rapid diagnosis of tuberculosis recurrence can be challenging due to persistently positive detection of Mycobacterium tuberculosis-specific DNA from sputum and bronchopulmonary samples in the absence of active disease.
Methods: We compared the diagnostic accuracy of the detection of M. tuberculosis-specific DNA by either Xpert (January 2010-June 2018) or Xpert Ultra (July 2018-June 2020) and M. tuberculosis-specific ELISPOT in bronchoalveolar lavage (BAL) samples with M. tuberculosis culture results from sputum or bronchopulmonary samples in patients with suspected recurrence of pulmonary tuberculosis. 
Results: Among 44 individuals with previous tuberculosis and a presumptive diagnosis of recurrent pulmonary tuberculosis, 4/44 (9.1%) were diagnosed with recurrent tuberculosis by culture. DNA of M. tuberculosis was detected by Xpert in BAL fluid in 1/4 (25%) individuals with recurrent tuberculosis and in 2/40 (5%) cases with past tuberculosis without recurrence, while BAL-ELISPOT with a cut-off of >4,000 early secretory antigenic target-6-specific or culture filtrate protein-10-specific interferon-γ-producing lymphocytes per 1 million BAL-lymphocytes was positive in 4/4 (100%) individuals with recurrent tuberculosis and in 2/40 (5%) cases of past tuberculosis without recurrence. 
Conclusion: M. tuberculosis-specific BAL-ELISPOT is more accurate than BAL-Xpert for the diagnosis of paucibacillary tuberculosis recurrence.
FACTORS AFFECTING URBAN PEOPLE’S INTENTION TO USE BUSES IN VIETNAM
Authors: THAI Nguyen Hong , QUAN Thach Minh
Published: April 2023

Despite strong development in Vietnam’s major cities, buses only contribute to city traffic. Bus services in Vietnamese towns do not yet meet passengers’ current needs and are not popular with passengers, especially in terms of time and convenience. This article analyzes the factors affecting urban people’s intention to use buses in Vietnam and, on that basis, makes recommendations to the authorities in cities to enhance the attractiveness of bus usage. Twenty-seven factors have been identified as affecting the need to travel by bus. The survey results show that there are still many barriers to attracting passengers using bus services in urban metropolitan areas. Therefore, urban governments in Vietnam need to adjust the current bus route network to suit the needs of the people, especially students, to increase its coverage.
A LOW-COST SYSTEM FOR SUPPORTING DRIVERS IN TRAFFIC JAMS
Authors: HOŁUBOWSKI Waldemar , FRANKIEWICZ Ryszard , KUSIŃSKI Sławomir , SIKORA Andrzej , ZIELONKA Adam
Published: April 2023

Cases of heavy traffic congestion (commonly referred to as traffic jams) have negative influences on the economy, public health, and social life. This makes it important to assist drivers in these situations with Internet of Things (IoT) systems. The aim of this article is to present a low-cost device that supports driving in traffic jams. The system, which is based on data from a laser sensor with a range of up to 40 m, controls the distances to vehicles in front of and behind a moving car. Through audio and video signals, it warns the driver whether the vehicle in front of or behind the equipped vehicle is too close. This allows the driver to control the distance and avoid minor collisions.
Factors Affecting the Adoption of Online Database Systems for Learning among Students at Economics Universities in Vietnam
Authors: Nguyen Thi Minh Phuong
Published: April 2023

This study aims to evaluate the determinants that influence the adoption of online databases in the learning process of students at economics universities in Vietnam. A quantitative study with a meta-analysis was conducted by utilizing structural equation modeling (SEM). The sample consisted of 492 students from economics universities located in Vietnam who were surveyed using stratified random sampling. The results indicate that the adoption of online databases in student learning is influenced by six determinants, namely: (i) perceived effectiveness, (ii) perceived ease of use, (iii) technical barriers, (iv) personal usefulness, (v) usage attitudes, and (vi) convenience. Our study has revealed that students' intention to use the online database system is positively influenced by their perceived ease of use and perceived usefulness. These findings could be valuable in shaping policies for enhancing the online database system at economics universities, taking into account the students' characteristics and the institution's needs.
The Frequency Spectrum Analysis of Wideband Oscillations of Grid-Connected Voltage Source Converter.
Authors: Wang Liyi , Cai Deyu
Published: April 2023

With the widespread application of Voltage Source Converter (VSC) in the power system with high penetration of renewable resources, the problem of wideband oscillations caused by the interaction between the power converters and the power grid has drawn large attention. This paper presents a new methodology for simplifying the mathematical derivations of the impedance model of VSC. Using the new simplified model, the stability and the spectrum characteristic of the performance of the VSC can be clearly analyzed. The proposed second-order d-q impedance model of the grid connected VSC at presence of PLL, not only mathematically proves that the wideband oscillatory modes always occurs in conjugate pairs, but also deliver a clear vision of the physical essence of the wideband oscillations. The classic modal analysis is executed in the paper to demonstrate the stability and frequency spectral characteristics of the wideband oscillations in the VSC integrated system. The impact of control parameters of the VSC on the wideband oscillatory stability is thouroughly analyzed using the results of the modal analysis. The methodology can be considered a powerful tool for the control design of VSC in the modern power system.
How Sustainable Transportation Can Utilize Climate Change Technologies to Mitigate Climate Change
Authors: Din Ashraf Ud , Ur Rahman Imran , Vega-Muñoz Alejandro , Elahi Ehsan , Salazar-Sepúlveda Guido , Contreras-Barraza Nicolás , Alhrahsheh Rakan Radi
Published: April 2023

The build-up of greenhouse gases (GHGs) is causing warmness in the Earth’s atmosphere, resulting in climate change. The transport sector is one of the active members of GHG emissions and it is imperative to use sustainable transport sources to control climate change. The measure aims to encourage citizens to stop using their private vehicles as their choice of transport and instead opt for joint sustainable mobility during traveling. In this study, a quantitative research method was used and data were collected from a sample of 410 respondents through questionnaire. On the other hand, study also took a simulation-based (N=10000) sample size of private vehicle data. The data were analyzed using structural equation modelling. The results revealed that sustainable transportation, climate change technologies and electric rail vehicles reduce climate change in the ecoregions of China. We conclude that sustainable transportation policies could be formulated and implemented to reduce climate change. In response to the research results, it is recommended that, since climate change is a multi-level governance issue and the outdated pyramidal transport industry models must be shifted to a sustainable transportation system model.
Everyone's an Artist? Exploring User Acceptance of AI-Based Painting Systems
Authors: Xu Junping , Zhang Xiaolin , Li Hui , Yoo Chaemoon , Pan Younghwan
Published: April 2023

Artificial intelligence (AI) applications in different fields are developing rapidly, among which AI painting technology, as an emerging technology, has received wide attention from users for its creativity and efficiency. This study aimed to investigate the factors that influence user acceptance of the use of AIBPS by proposing an extended model that combines the Extended Technology Acceptance Model (ETAM) with the AI-based Painting System (AIBPS).A questionnaire was administered to 528 Chinese participants, using validated factor analysis data and Structural Equation Modeling (SEM) was used to test the hypotheses. The findings showed that hedonic motivation (HM) and perceived trust (PE) had a positive effect (+) on users' perceived usefulness (PU) and perceived ease of use (PEOU), while previous experience (PE) and technical features (TF) had no effect (-) on users' perceived usefulness (PU). This study provides an important contribution to the literature on AIBPS and the evaluation of systems of the same type, which helps to promote the sustainable development of AI in different domains and provides a possible space for further extension of TAM, thus helping to improve the user experience of AIBPS. The results of the study provide insights for system developers and enterprises to better motivate users to use AIBPS.
Effect of Celery (Apium graveolens L.) Microgreens on Drosophila melanogaster
Authors: Salim Mohamad Agus , Subandi Muhammad , Yuniarti Yeni
Published: April 2023

Celery (Apium graveolens L. ; family : Apiaceae) was often used as a spice in daily food. However, this plant contains many antioxidant compounds useful for attenuating neurodegenerative disorders including Parkinson's disease. Planting celery in the form of microgreens harvested 15 days was expected to increase the content of bioactive compounds. In the current study, we intended to evaluate the neuromodulatory potential of methanol extract of celery microgreens on fruit flies (Drosophila melanogaster Meigen : family Drosophilidae ; ordo : Diptera) which were exposed to paraquat. Neuroprotective capacity was assessed by survival rate, locomotor performance, lipid peroxidation and dopamine content after being treated with 120 µg/mL extract of celery microgreens and 3.5 mM paraquat for 4 days. Phytochemical constituents from extract of celery microgreens were measured including total polyphenol content and antioxidant activity using the radicals scavenging method. Exposure of adult fruit flies to paraquat will cause a decrease in the survival and locomotor phenotype improved by extract of celery microgreens treatment. In parallel, increased malondialdehyde content from lipid peroxidation and decreased dopamine content can be improved by the presence of celery microgreens extract. Neuroprotective capacities indicate a high content of antioxidant compounds of celery microgreens extract. Our study concludes that celery microgreens exhibited to retard the effect of oxidative stress that causes Parkinson's disease.
Simultaneous Determination of Binary Mixture of Estradiol and Progesterone Using Different Spectrophotometric Methods
Authors: Ali Dashty K. , Fakhre Nabil A. , Rasheed Chnar M.
Published: April 2023

Four rapid, accurate and very simple derivative spectrophotometric techniques were developed for the quantitative determination of binary mixtures of estradiol (E2) and progesterone (PRG) formulated as a capsule. Method I is the first derivative zero-crossing technique, derivative amplitudes were detected at the zero-crossing wavelength of 239.27 and 292.51 nm for the quantification of estradiol and 249.19 nm for Progesterone. Method II is ratio subtraction, progesterone was determined at λmax 240 nm after subtraction of interference exerted by estradiol. Method III is modified amplitude subtraction, which was established using derivative spectroscopy and mathematical manipulations. Method IIII is the absorbance ratio technique, absorbance of both medicines was measured at two wavelengths λ1= 260, -absorptive point and λ2=240max of progesterone. The Q equations were used to calculate the final concentrations. The calibration curve is linear from 5.0–140 and 2.0–32.0 µg/ml for estradiol and progesterone respectively. The proposed techniques' selectivity was tested using synthetic combinations created in the lab and assessed using the standard addition method. Using one-way ANOVA, the outputs of the proposed ways were compared, and the result showed no significant differences between the proposed techniques.
Lithofacies, Deposition, and Clinoforms Characterization Using Detailed Core Data, Nuclear Magnetic Resonance Logs, and Modular Formation Dynamics Tests for Mishrif Formation Intervals in West Qurna/1 Oil Field, Iraq
Authors: Al-Dujaili Ahmed N. , Shabani Mehdi , Al-Jawad Mohammed S.
Published: April 2023

This study considered the complexity of Mishrif geology and its effect on fluid movement within and across Mishrif reservoir intervals. For this purpose, we analyzed the following items: the multiple interval communication with high permeability contrast, the geological setting of the upper Mishrif (mA) interval, the channel structure in the Lower Mishrif-Part 1 (mB1) interval, the thin layers in the upper part of Lower Mishrif-Part 2 (mB2U) of very high permeability, and the microporous interval of the lower part of Lower Mishrif-Part 2 (mB2L); none of them were well defined before this work. The bottom interval of Mishrif or Rumaila (mC) is predominantly microporous, and the best reservoir is at the top of intermediate quality. Two high-porosity layers are systematically found in the mC unit, which is casually referred to as “rabbit ears.” The mB2L contains grainstones in the far north of the West Qurna/1 oil field (WQ1). In the south of mB2L, some of the toe sets from the clinoforms in a distal depositional setting have developed into rather important vertical pressure baffles and barriers to vertical flow.

The mB2U generally consists of grainstones with thin streaks of mudstone high flow layers (HFLs), and the rocks underneath are described generally as grainstone shoals. About 80% of stock tank oil originally in place (STOOIP) in mB2U exists in grainstones. There are no known microporous reservoirs in mB2U. The pressure difference across the boundaries between mB1 and mA can be positive or negative. At the base, mB1 channels are always in pressure communication with the mB2U below. The best flow from the mA comes from HFLs, which are found around faults. Reservoir quality within mA is generally best in the first section of the upper Mishrif (mAa), and the majority of STOOIP in mA exists in microporous rocks, while some 30% of STOOIP is contained in grainstones.
In-Depth Laboratory Proppant Transport Study Using HVFRs for Marcellus High TDS Environments
Authors: Biheri Ghith , Imqam Abdulmohsin
Published: April 2023

Excellent proppant transport can be accomplished by introducing high-viscosity friction reducer (HVFR) fracture fluids. However, HVFRs face several challenges that prevent these fluids from providing good proppant transport performance, including the presence of total dissolved solids (TDS) in the produced water. TDS can negatively impact the viscous and elastic properties of HVFR. This study evaluated the rheological and proppant transport performance using HVFRs at extreme salinity conditions using water samples from the Marcellus Basin. The anionic and cationic HVFRs with a concentration of 4 gpt were used. Experimental evaluation work, including the rheology, static proppant settling measurements, and dynamic proppant transport, was conducted using three Marcellus TDS concentrations (68,000; 137,000; and 229,000 ppm). All the experiments were performed at a high-temperature condition that mimics the Marcellus reservoir temperature of 65.5°C (150°F). The results show that the existence of TDS was largely impacted by both types of HVFRs, but the cationic HVFR exhibited better resistance to the Marcellus TDS compared to the anionic HVFR in terms of transporting proppant. The viscosity of the anionic HVFR was reduced more than that of the cationic HVFR, as TDS concentrations increased to 229,000 ppm. However, the elasticity of both HVFRs was weak, as a switch was made from using low TDS to high TDS. This could imply that HVFR viscosity provides the main contribution to proppant transport in high TDS environments. Therefore, it is crucial to evaluate the impact of TDS on the effectiveness of HVFR by investigating HVFR rheology, static proppant settling, and dynamic proppant transport in the TDS environment.
The volatilome reveals microcystin concentration, microbial composition, and oxidative stress in a critical Oregon freshwater lake
Authors: Collart Lindsay , Jiang Duo , Halsey Kimberly
Published: April 2023

Toxins commonly produced by cyanobacterial blooms in freshwater lakes are a serious public health problem. The conditions leading to toxin production are currently unpredictable, thereby requiring expensive sampling and monitoring programs globally. We explored the potential of volatile organic compounds (VOCs) to indicate microcystin presence and concentration, and microbial community composition in Upper Klamath Lake, OR. Elastic net regularization regression selected 29 of 229 detected m/z+1 values (corresponding to unique VOCs) in models predicting microcystin toxicity that outperformed or significantly improved upon regression models based on environmental parameters, including chlorophyll, pH, and temperature. Several m/z+1 values selected by elastic net were putatively identified as saturated fatty aldehydes (SFAs), which are important in defending cyanobacteria against oxidative stress. Unique sets of m/z+1 values were also identified by elastic net regression that predicted the relative abundance of the most dominant bacterial phyla, classes, and cyanobacterial genera. These results show that VOCs may be a key component of lake monitoring strategies.