bluuebunny/crossref_metadata_2025 huggingface dataset:
Labour mobility and international trade
Authors: Guo Yanrong
Published: September 2023

Motivation: The academic debate on whether the relationship between factor mobility and international trade is one of complementarity or substitution is inconclusive. In general, the relationship between the two can vary depending on the specific research methodology and the object of study. Moreover, there are fewer empirical analyses with China and the European Union as subjects, so studying the relationship between labour mobility and trade in the case of China and Europe is worthwhile.
Aim: The purpose of this paper is to determine, through empirical analysis, the relationship between labour mobility in the form of dispatched labour and bilateral trade between China and the European Union in the period of 2005-2021.
Materials and methods: This paper utilises quantitative analysis to investigate the relationship between labour movements and trade (imports and exports) based on data from 2005 to 2021, primarily through co-integration analysis and Granger causality testing.
Results: The study found that there is a substitution relationship between the number of dispatched labour from China and the trade in goods between China and the European Union in the research period. Additionally, Granger causality tests show that China's dispatched labour to the EU is the Granger cause of China-EU export trade, and vice versa. However, China's dispatched labour to the EU is not a Granger cause of China-EU import trade.
Financialization as one of the sources of contemporary economic crises
Authors: Tyński Aleksander , Witkowski Witold , Wróblewski Jarosław
Published: September 2023

Motivation: Financialization is a multidimensional, complex process, which is currently developing very strongly and which can affect the economy in a positive or negative way. A positive impact usually materializes in the form of an increase in the level of GDP, and a negative one in the form of supremacy of the financial area over the real sphere, an increase in the role of financial activity of non-financial entities, and even the autonomy of the financial sphere in relation to the real sphere.Aim: The purpose of this article is to identify and assess the impact of the financialization process on the modern economy and to look at this process as one of the potential sources of financial crises. This article focuses on the negative effects of financialization and uses the example of the American crisis of 2008.Materials and methods: review and critical review of the literature and reports from the financial sector, with particular emphasis on the negative impact of financialization on the US financial sector in 2008.Results: The first part presents the essence and characteristics of financialization and attempts to systematize this process. In the second part, financialization was looked at through the prism of the risk it brings, the materialization of the effects of which may lead to serious economic turbulence, and even to financial crises. The level of these effects was presented and assessed, as well as the methods of action of the American government, which contributed to minimizing the effects of the 2008 crisis, but which at the same time cannot be considered effective in the fight against financialization.
kontinentális és angolszász jogrendszer kölcsönhatása a FIDIC Sárga Könyv tükrében
Authors: Boros Sándor
Published: September 2023

A Tanácsadó Mérnökök Nemzetközi Szövetsége által megalkotott ún. FIDIC Könyvek az építési beruházások vonatkozásában, a projekt típusa szerint különböző szerződéses mintákat tartalmaznak, melyeknek az elsődleges célja a legjobb gyakorlat összefoglalása, és az arányos kockázatmegosztás. A FIDIC Könyvek a legnépszerűbb joganyagnak minősülnek világszerte az építési projektek vonatkozásában. A Sárga Könyv a második leggyakrabban használt szerződéses minta, melynek lényege, hogy a vállalkozó kötelezettsége a tervek elkészítésére és a kivitelezésre is kiterjed. A Sárga Könyv az angolszász jogrendszer jogelveit és jogintézményeit alkalmazza, melyből következik, hogy a szerződéses minta kontinentális jogi környezetben való alkalmazása számos jogértelmezési és jogalkalmazási problémát vet fel. A tanulmány a Sárga Könyv kontinentális jogi környezetben való értelmezésének a bemutatását követően a vállalkozó késedelemből eredő károkért való felelősségének kérdésével foglalkozik. A szerző a vizsgálódás középpontjába azt az esetkört állítja, amikor a vállalkozó késedelmét a megrendelő okozta. A szerző ebben a körben konkrét jogalkalmazási javaslatot fogalmaz meg.
munkaviszony munkáltató általi jogellenes megszüntetésének jogkövetkezményei a munka törvénykönyvéről szóló 2012. évi I. törvény tükrében
Authors: Kormos János
Published: September 2023

A dolgozat a munkaviszonyra vonatkozó szabályokból kiemelve a munkaviszony munkáltató általi jogellenes megszüntetésének jogkövetkezményeit bemutatja annak közelmúltbeli rövid történeti hátterét, fejlődési irányát, a jelenlegi szabályozását, de legfőképpen a munka törvénykönyvéről szóló 2012. évi I. törvény (Mt.) 82. § (1), (2) és (4) bekezdése gyakorlati alkalmazásának immár több, mint tíz év alatt felgyűlt ítélkezési tapasztalatait. A dolgozat kitér a szóban lévő munkáltatói döntésekkel szemben előterjesztett munkajogi igények jogalapját, valamint összegszerűségét érintő kérdésekre is, segítségül hívva a felsőbb-bíróságok, tehát akár az ítélőtáblák, akár a Kúria hasonló tárgyban meghozott, a jogalkalmazás során iránymutatónak tekinthető eseti döntéseit.
Comparative leaf structural analysis of Nepeta nuda l. Plantlets, regenerated from cryopreserved shoot meristem and ex vitro-adapted plants
Authors: Stefanova Miroslava , Ganeva Tsveta , Koleva Dimitrina
Published: September 2023

The leaf anatomy and chloroplast ultrastructure of Nepeta nuda L. plantlets regenerated in vitro from cryopreserved shoot apical meristem and in vitro-micropropagated plantlets were studied comparatively to assess whether cryoprocedure affected leaf morphogenesis. Both postcryo and in vitro plantlets failed to develop a distinguishable palisade layer, making the mesophyll appear homogeneous. Significant damage to the chloroplast envelope and substantial thylakoid ruptures were also observed. We assumed that the specific in vitro conditions more likely affected the structures than the cryotreatment itself. Light and transmission electron microscopy observations were also carried out on newly formed leaves of ex vitro-adapted plants. The examined leaf features were similar to those in the in situ plants – bifacial leaf lamina, double-layered palisade parenchyma, loosely arranged spongy parenchyma cells, and chloroplasts with intact envelope and evenly distributed throughout the stroma internal membrane system. The obtained histological and ultrastructural results revealed the retained morphogenetic potential of N. nuda plants and proved cryopreservation as a suitable method for long-term storage.
Influence of the propagation method of three semidwarf rootstocks on the growth and activity of the physiological processes of maiden sweet cherry trees in a nursery
Authors: Świerczyński Sławomir
Published: September 2023

Rootstocks that reduce the vigor of sweet cherry trees are currently in high demand in orchard production. However, their suitability for nursery production is not fully verified. There are also difficulties in the method of their obtaining, mainly through in vitro cultures, which is associated with high prices. The experiment compared the growth of maiden trees of four sweet cherry varieties on rootstocks that reduce their vigor, ‘Gisela 5’, ‘Krymsk 5;, and ‘Pi-ku 1’. In addition, rootstocks produced by cheaper means using shoot cuttings were evaluated compared with those from in vitro. The lower efficiency of maiden trees was obtained on the ‘Krymsk 5’ rootstock than on the other two rootstocks. In contrast, the vigor of maiden trees on this rootstock was significantly more potent. Generally, rootstocks derived from in vitro yielded a higher percentage of maiden trees. Additionally, for most of the varieties and years tested, the rootstocks obtained in this way improved the growth of the trees as determined by their diameter and length of the lateral shoots. The activity of the physiological processes of the maiden trees varied with the rootstock used. Maiden trees on the ‘Krymsk 5’ rootstock were most often characterized by the lowest levels of the three tested parameters (E, C, and I CO2). Meanwhile, the net photosynthetic intensity was lowest on the ‘Pi-ku 1’ rootstock.
Prognostic indicators for survival in surgically managed small intestinal obstruction in pet rabbits: 141 presentations (2011–2021)
Authors: Sheen Joanne C. , Sladakovic Izidora , Finch Sue
Published: September 2023

OBJECTIVE

To determine prognostic relevance of various patient factors and intraoperative variables associated with surgical management of small intestinal obstruction in pet rabbits.

ANIMALS

114 pet rabbits with 141 presentations of small intestinal obstruction treated surgically between June 2011 and December 2021.

METHODS

In a retrospective observational study design, medical records were reviewed for rabbits with small intestinal obstruction that had undergone surgical intervention. Data were collected on variables of interest and outcome (survival to hospital discharge). Univariable and multivariable logistic regression analyses were performed to identify variables associated with survival.

RESULTS

Overall survival was 75.2% (106/141). Specifically, 95.7% (22/23) of presentations involving rabbits < 25 months survived. The odds of survival on univariable modeling were significantly lower in presentations of rabbits > 72 months compared with those < 25 months (OR, 0.05; 95% CI, 0.01 to 0.40; P = .005). Rectal temperature, clinicopathologic findings, etiology of obstruction, presence of full-thickness gastrointestinal wall injury, and previous small intestinal obstruction surgery did not show significant effects on survival. In a multivariable model that controlled for plasma potassium and calculated plasma osmolarity and tonicity, the odds of survival in presentations of rabbits > 72 months were 95% lower than those < 25 months (OR, 0.05; 95% CI, 0.01 to 0.50; P = .012).

CLINICAL RELEVANCE

Surgical intervention should be considered a suitable treatment option for small intestinal obstruction in rabbits < 72 months and carried a good prognosis. The most common etiology was consistent with a compressed hair pellet, and extraluminal digital manipulation into the cecum was a successful surgical technique in most presentations.
Ressignificação dos conceitos de vigilância digital, estado de exceção, globalização e narrativa marcial em Byung-Chul Han, Giorgio Agamben, Domenico De Masi e Slavoj Žižek
Authors: H. Villas Bôas Castelo Branco Pedro , Barbosa Gouvêa Carina
Published: September 2023

O auge da pandemia provocada pela pandemia levou muitos pensadores a refletir sobre o “cenário distópico” que resultou no estado de exceção em saúde pública global. A pesquisa examina questões controvertidas pelas discussões de Byung-Chul Han, Giorgio Agamben, Domenico De Masi e Slavoj Žižek. Para este fim foi mapeado as principais questões suscitadas pelos pensadores em suas recentes publicações para mostrar seus aportes e limites. A pesquisa discute de forma crítica-dialética pontos polêmicos que vão desde o questionamento da adoção do estado de emergência em saúde pública de importância internacional, os limites e alcance da globalização e a eficácia do uso da retórica marcial que declara guerra ao vírus ao designá-lo como inimigo. Concluímos que um deslocamento de um problema sanitário global, que requer cooperação internacional e responsabilidade coletiva, para uma questão marcial tende a encobrir os reais problemas epidemiológicos, reforça a polarização, hostilidade e a busca de culpados. O uso da retórica bélica mais do que provocar cooperação e apoio a medidas impopulares estimula inimizades e, a depender das circunstâncias, serve de pretexto para autocratas eleitos restringirem direitos. Dada esta exposição panorâmica do texto o caminho metodológico adotado é o da pesquisa bibliográfica e documental.
Fatal thrombotic microangiopathy in an infant with COVID-19: a case report
Authors: Nakip Özlem Sarıtaş , Kesici Selman , Terzi Kıvanç , Orhan Diclehan , Bayrakcı Benan
Published: September 2023

Background. While macrovascular thrombosis is common in adult COVID-19 patients, thrombotic microangiopathy as a part of endothelitis might play an important role in severe organ dysfunction. Thrombocytopenia-associated multiple organ failure (TAMOF) is a thrombotic microangiopathy syndrome that is associated with endothelial damage. Herein, we aim to report a pediatric TAMOF case related to SARS-CoV-2 infection which has been scarcely reported to date.
Case. A 7-month-old boy who became severely ill after being infected with SARS-CoV-2 required advanced critical care treatments such as continuous renal replacement therapy, therapeutic plasma exchange, and extracorporeal membrane oxygenation. A heart and lung biopsy obtained during sternotomy showed thrombotic microangiopathy. Despite early plasma exchange, mortality was inevitable because of severe liver failure.
Conclusions. This case report implies that SARS-CoV-2 infection could cause TAMOF in children. To the best of our knowledge, this is the second SARS-CoV-2-induced pediatric TAMOF case. More studies are needed to determine alternative treatments for patients with TAMOF who are resistant to conventional therapies.
Rehospitalization indications of children hospitalized for COVID-19 infections after discharge: Should we suspect long COVID?
Authors: Cem Ela , Bayram Nuri , Özenen Gizem Güner , Kara Aybüke Akaslan , Gülderen Mustafa , Çelebi Miray Yılmaz , Şahinkaya Şahika , Böncüoğlu Elif , Kıymet Elif , Devrim İlker
Published: September 2023

Background. Complications that may develop in children after coronavirus disease 2019 (COVID-19) infections are unknown. The `Long COVID` syndrome is a new process that can also be identified in children. Therefore, in this study, the conditions that may develop in children after COVID-19 infection were discussed, and the indications for rehospitalizations were reviewed.
Methods. This retrospective cohort study was conducted in a tertiary children`s hospital in İzmir, Türkiye. All children who were rehospitalized in the study center after discharge, and the indications for readmissions were screened.
Results. Since the beginning of the pandemic, 777 children with COVID-19 infection were hospitalized, including 98 (12.6%) cases rehospitalized for any indication. Fifty-five (56.1%) patients were male, and 43 (43.9%) were female. The mean age of the study population was 79.3±63.5 months (1 month to 17 years). Among these 98 patients, 76 (77.6%) were rehospitalized because of the presence of their primary underlying disease, nonspecific infectious diseases unrelated to COVID-19, and the need to perform certain surgical procedures. The remaining 22 (22.4%) patients presented with symptoms such as fatigue, fever, abdominal pain, and myalgia after the COVID-19 infection. No other underlying cause was detected in approximately one-third of the patients, whose manifestations were found to be consistent with long COVID syndrome.
Conclusions. The findings of acute COVID-19 infection are well characterized, but there is still limited data on its long-term outcomes. The majority of the study population that had no underlying disease were thought to have complications from the COVID-19 infection. Therefore, although the incidence rate of long COVID syndrome in childhood has not been revealed so far, it should be kept in mind among relevant differential diagnoses.
The effects of measures taken during the COVID-19 pandemic on the seasonal dynamics of respiratory viruses in children
Authors: Karbuz Adem , Aktaş Elif , Tutak Gülten Aydın , Barış Ayşe , Beşel Leyla , Emre Irmak , Kırmacı Çiğdem , Kılıçaslan Önder , İşançlı Didem Kızmaz , Arat Zübeyde
Published: September 2023

Background. We aimed to evaluate the effects of public health measures taken during the COVID-19 pandemic on respiratory viruses.
Methods. The study was conducted between February 1, 2021 and December 1, 2022. Patients aged 1 month to 18 years hospitalized for infectious diseases were tested for SARS-CoV-2 and respiratory viruses by multiplex PCR.
Results. Of the total 1173 patients, 56.2% were male and 43.8% were female, and 47.5% of the patients were under 24 months of age. The viruses detected were SARS-CoV-2 31.9%, human rhinovirus/enterovirus 19.4%, respiratory syncytial virus (RSV) 9.3%, parainfluenza virus 7%, adenovirus 6%, seasonal coronavirus 5.2%, bocavirus 3.8%, influenza 3.1%, and metapneumovirus 2.8%. Among the patients, 386 were hospitalized with lower respiratory tract infections, 238 with upper respiratory tract infections, 202 to evaluate fever etiology, 111 with acute gastroenteritis and 236 with other diagnoses. Of these patients, 113 were admitted to the intensive care unit. Intensive care unit admission rates were statistically significantly higher for bocavirus and RSV, in those hospitalized between July 1, 2021 and July 1, 2022 (first period when schools were held full-time face-toface at all grades) and in children aged 1-24 months.
Conclusions. Public health measures taken during the COVID-19 pandemic have affected the seasonal distribution of respiratory viruses and the severity of illness in children.
COVID-19 Pandemisi Sürecinde Tip 2 Diyabetli Bireylerin Vitamin-Mineral ve Bitkisel Ürün Kullanımlarının Değerlendirilmesi: İzmir İli Örneği Kesitsel Araştırma
Authors: KANER Gülşah , BAKIR Buse
Published: September 2023

Amaç: Bu araştırmanın amacı, COVID-19 pandemi sürecinde tip 2 diyabetli bireylerin vitamin-mineral ve bitkisel ürün kullanımlarının

değerlendirilmesidir.

Gereç ve Yöntemler: Kesitsel ve tanımlayıcı tipteki bu araştırma, İzmir ilinde yaşayan 246 tip 2 diyabetli birey ile yürütülmüştür.

Bireylerin sosyo-demografik özellikleri, vitamin-mineral ve bitkisel ürün kullanımları sorgulanarak anket formuna kaydedilmiştir.

Bireylerin vücut ağırlığı (kg) ve boy uzunluğu (cm) ölçülerek, Beden kütle indeksi (BKİ, kg/m2) hesaplanmıştır.

Bulgular: Bireylerin yaş ortalaması 54,68 ± 8,62 yıl olup, %26’sı erkek (n=64), %74’ü kadındır (n=182). COVID-19 öncesi dönemde

vitamin-mineral kullananların oranı %36,6 (n=90) iken, bu oran COVID-19 sürecinde anlamlı artış göstermiştir (%52,4; n=129;

p
Tip 1 Diabetes Mellitus Tanılı Hastalarda Poliglandüler Otoimmün Sendrom Sıklığının Tespiti ve Diyabetin Prognoz ve Komplikasyonları ile İlişkisinin Araştırılması
Authors: ACAR Rabia , KİLİNC Faruk
Published: September 2023

Amaç: Tip 1 diabetes mellitus (T1DM) tanılı hastaların üçte birinde otoimmün poliglandüler sendrom (OPS) bulunmaktadır. Çalışmada

T1DM’ye eşlik eden OPS sıklığı ve diyabetin prognoz, komplikasyonları ile ilişkisinin araştırılması amaçlanmıştır.

Gereç ve Yöntemler: Çalışmaya Endokrinoloji polikliniğine başvuran ve T1DM tanısı ile takipli 99 hasta dahil edildi. Verilerin analizinde

Ki-Kare analizi (Pearson Chi-kare), Kolmogorov-Smirnov testi, Student t-testi, Mann Whitney-U testi, Spearman Korelasyon testi ve

Kruskal Wallis testi kulanılmıştır. Verilerin analizinde SPSS 22 paket programı kullanıldı. Anlamlılık değeri p≤ 0,05 olarak alındı.

Bulgular: Çalışmaya alınan hastaların 25’inde (%25,3) hipotiroidi ve 8’inde (%8,1) çölyak hastalığı saptandı. Hastaların 9’unda (%9,1)

anti endomisyum antikor, 50’sinde (%50,5) adacık antikoru, 22’sinde (%22,2) anti insülin antikor, 26’sında (%26,3) anti parietal antikor,

8’inde (%8,1) doku transglutaminaz IG A, 43’ünde (%43,4) ANA, 4’ünde (%4,0) ASMA pozitifliği ve 25’inde (%25,3) OPS varlığı tespit

edildi. T1DM tanılı hastalarda retinopati, nöropati ve nefropati gelişen hastaların hastalık süresi gelişmeyenlerin hastalık süresinden

anlamlı şekilde yüksek olduğu tespit edildi. Hastaların hastalık yılı ile VKİ ve bel çevresi arasında pozitif yönde, hastalık yılı ile HbA1c

ve c peptit arasında ise negatif yönde anlamlı bir korelasyon saptandı. OPS varlığı arasında retinopati varlığı, nöropati varlığı ve nefropati

varlığı açısından anlamlı farklılık olmadığı saptandı. Bunun yanında OPS varlığı arasında HbA1c değeri açısından da anlamlı farklılık

görülmedi.

Sonuç: T1DM tanılı hastalarda diğer otoimmün hastalıkların sıklığında yıllar geçtikçe ciddi bir artış gelişmekte olup, diyabetik hastaların

takiplerinde komplikasyon risklerinin azaltılması, iyi bir prognoz, iyi klinik gelişim ve erken tanı açısından otoimmün hastalıkların

diyabetin hem tanı anında hem de ilerleyen yıllarında dikkate alınması gerekmektedir
Yoğun Bakım Hemşirelerinin Obez Hastalara Karşı Tutumları ile Bakım Verme Davranışları Arasındaki İlişkinin İncelenmesi
Authors: POLAT DÜNYA Cansu , KARAGÖZ Esra , ÇELİK Melike
Published: September 2023

Amaç: Araştırmanın amacı yoğun bakım hemşirelerinin obez hastalara karşı tutumları ile bakım verme davranışları arasındaki ilişkinin

incelenmesidir.

Gereç ve Yöntemler: Tanımlayıcı ve ilişki arayıcı nitelikte olan bu çalışma Ekim 2022-Şubat 2023 tarihinde bir şehir hastanesinin

yoğun bakım ünitelerinde görev yapan 204 hemşire ile gerçekleştirildi. Veriler tanıtıcı bilgi formu, Obezite Önyargı Ölçeği ve Bakım

Davranışları Ölçeği kullanılarak çevrimiçi anket (Google Forms) uygulaması ile toplandı. Veriler tanımlayıcı istatistiklerin yanı sıra

bağımsız gruplarda t-test, One Way Anova ve Pearson korelasyon ile analiz edildi.

Bulgular: Hemşirelerin yaş ortalaması 26,17±2,35 yıl olup, %95,1’i lisans mezunu idi. Yoğun bakım deneyim süresi 2,39±1,88 yıl idi.

Hemşirelerin %81,9’u mesleğini severek yaptığını, %62,7’sinin obez hastaya bakım vermek istemediğini, %52,9’u obezite konusunda

eğitim almadığını ve %94,1’i obez hastaya bakım verirken zorlandığını belirtti. Hemşirelerin Obezite Önyargı Ölçeği puan ortalaması

86,37±8,53 olup %38,2’sinin ön yargıya eğilimli, %59,8’inin ön yargılı olduğu saptandı. Obezite Önyargı Ölçeği toplam puanı ile yaş

arasında istatistiksel olarak anlamlı negatif yönlü bir ilişki bulundu (p= 0,045). Bakım Davranışları Ölçeği puan ortalaması 5,38±0,56

olup hemşirelerin bakım kalitesine ilişkin algılarının yüksek olduğu belirlendi. Araştırmada hemşirelerin Bakım Davranışları Ölçeği ile

Obezite Önyargı Ölçeği arasında anlamlı bir ilişki bulunmadı (p= 0,240).

Sonuç: Yoğun bakım hemşirelerinin tamamına yakınının obez hastalara karşı önyargılı ve önyargıya eğilimli olduğu, bakım kalitesine

ilişkin algılarının ise yüksek olduğu bulundu. Obezite önyargı düzeylerinin bakım davranışları üzerine etkili olmadığı saptandı. Bu

durum hemşirelerin obez hastalara karşı bakım davranışlarında ön yargılarından ziyade mesleki değerlerin etkili olduğunu düşündürmektedir.
The Relationship Between Obesity with Depression and Anxiety Levels: a Cross-Sectional, Case-Control Study
Authors: BALKOCA Fatma , CUBUKCU Mahcube , ŞİMŞEK YURT Nur
Published: September 2023

Aim: This study aims to investigate the relationship between obesity and depression and anxiety by determining the depression and

anxiety levels of obese and non-obese patients.

Material and Methods: This study was carried out between 01.02.2022 and 30.04.2022 at Samsun University Faculty of Medicine.

Among all the patients registered in the obesity center, 110 patients who met the inclusion criteria and 110 non-obese patients who

applied to the family medicine clinic as the control group were included in the study. Data were collected through a questionnaire

formed using sociodemographic characteristics, Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI).

Results: The study encompassed of 220 patients, among whom 144 individuals (constituting 65.5% of the sample) were identified as

female. Depression and anxiety levels were higher in obese subjects than in non-obese subjects (p=0.020, p=0.040, respectively). Once

the body mass index (BMI) groups of the participants were compared according to BDI and BAI, severe depression symptoms and severe

anxiety symptoms higher in the morbidly obese group. The difference between the groups according to both BDI and BAI was found to

be statistically significant (respectively; p=0.005, p=0.008). The presence of moderate and severe depression and anxiety symptoms were

determined as independent risk factors for the development of obesity (respectively; OR=5.329, 95% CI 2.98-13.41, p=0.012; OR=3.452,

95% CI 1.56-7.89, p=0.023).

Conclusion: This study revealed that the prevalence of depression and anxiety symptoms was found to be high in obese individuals. It

was observed that as BMI increased, the severity of depression and anxiety symptoms increased.
Sıçanlarda REM Uyku Yoksunluğunun İskelet Kası Myostatin Düzeylerine Etkisi
Authors: İLERİ İsmetcan , TURAN İnci
Published: September 2023

Amaç: Uyku, kas metabolizması için önemli faktörlerden biridir. Uyku yoksunluğunun (UY) kas rejenerasyonunu bozduğu gösterilmiştir.

Myostatin iskelet kası hücreleri tarafından eksprese edilir ve kas büyümesini sınırlandırır. Çalışmamızın amacı, sıçanlarda akut uyku

yoksunluğunun iskelet kası myostatin düzeyleri üzerindeki etkilerini değerlendirmektir.

Gereç ve Yöntemler: Yirmi bir erkek Wistar albino sıçan (200-250g) rastgele üç gruba (n=7) ayrılmıştır: Kontrol grubu, Geniş platform

(GP) grubu ve UY grubu. REM UY, 72 saat boyunca modifiye çoklu platform yöntemi kullanılarak indüklenmiştir. Lökomotor aktivite

gruplar arasında açık alan testi (OFT) kullanılarak değerlendirilmiştir. Gastroknemius ve soleus kas dokuları alınmış ve kas dokularında

myostatin, malondialdehit (MDA), glutatyon (GSH) ve glikojen seviyeleri ölçülmüştür.

Bulgular: Bu çalışma, akut UY’nin kontrol grubuna kıyasla soleus kasında myostatin (1161±39,55) ve MDA (115,37±8,47) seviyelerinde

artışa neden olduğunu göstermiştir (sırasıyla p=0,036 ve p=0,01). OFT’de geçilen kare sayısı diğer gruplarla karşılaştırıldığında artmıştır

(56,33±22,02) (p=0,001 ve p=0,044). Gastroknemius kasında GSH (4,86±0,26) ve glikojen seviyeleri (5,13±0,21) UY grubunda azalmıştır

(sırasıyla p=0,007 ve p=0,028).

Sonuç: Bu veriler, REM uyku yoksunluğunun iskelet kasındaki myostatin seviyelerini ve oksidatif stres parametrelerini farklı kas tiplerinde

farklı miktarlarda değiştirerek kas metabolizmasını etkilediğini gösterebilir.
Pulmonary exacerbation of cistic fibrosis by Brevibacterium sp in a child: case report and literature review
Authors: Yahiro Davi , Viana Tayná , Yecker Gustavo , Lima Matheus , Azzi Renata , Andrade Maria Izabel , Alcântara Lisandra , Pereira Heitor , Giesteira Eduarda , Quintão Sofia , Moraes Marcos Vinícius , Moura Matheus , Araújo Andre
Published: September 2023

Cystic fibrosis (CF) is an autosomal recessive disease that usually affects the respiratory tract causing recurrent infections and deterioration of lung function. Other organs such as the digestive system and pancreas are also affected. In this report, we describe an 8-year girl with CF, previously colonized with Pseudomonas aeruginosa that developed pulmonary exacerbation not responsive to empiric treatment of broad spectrum antibiotics directed against prior colonization. Brevibacterium sp was detected in culture of bronchoalveolar lavage during bronchoscopy. Antimicrobial treatment was changed to vancomycin, meropenem, amikacin and ciprofloxacin with clinical, laboratorial and radiologic improvement after 23 days of treatment. Patient received discharge 30 days after admission for ambulatory follow-up. Its important that healthcare workers consider the possibility of atypical agents causing pulmonary exacerbation in patients with cystic fibrosis, mainly in children with initial failure of empiric treatment.
Expanding the applicability of ultrasonography in the neonatal sphere: in addition to cerebral hemorrhages
Authors: Rosa Julia , Rasche Milena , Araujo Gabrielly , Matsuoka Marcia , Falcão Mário , Bianchini Fabiola , Cardoso Laura , Suzuki Lisa
Published: September 2023

ABSTRACT Introduction: Neonatal ultrasound began in the 1970s to evaluate cerebral hemorrhages. With the advent of different transducers and improvement of the technological devices (Doppler function), its use has greatly expanded, being possible the evaluation many organs. Objectives: The study aims to show new applicability of ultrasonography, as an auxiliary method in the diagnosis of spinal alterations, pulmonary diseases, and cranial sutures in the neonatal period. Methods: Descriptive study of ultrasound examinations performed with the Logiq P7 device of General EletricT, with multifrequency and microconvex transducers with frequency of 3 to 11 MHz and linear with frequency of 2 to 11 MHz. Ultrasound evaluations were performed immediately after diagnostic suspicion, by a specialist physician with more than 15 years of experience in pediatric ultrasound, provided that the clinical condition of the newborn allowed the examination and, if there was a need, a new ultrasound would be performed for diagnostic confirmation. Residência Pediátrica; 2023: Ahead of Print DOI: 10.25060/residpediatr-2023-836 Nota aos leitores: pode haver informações pendentes, por se tratar de um artigo em “visualização pré-publicação”. Results: Presentation of ultrasound images performed routinely in a neonatal tertiary-level unit, including evaluations of spine, lungs and skull bones presented as well: 1.Ultrasonography of normal neonatal spine (medullary cone and cauda equina). 2.Normal neonatal chest ultrasound, with the presence of A-lines and rare B-lines, and graphic representation of normal diaphragmatic mobility. 3.Ultrasound of the pervious and closed sagittal cranial suture. Conclusions: Ultrasonography has several applicability, and its use in the neonatal population favors satisfactory the diagnosis and follow-up of various pathologies, in a noninvasive and innocuous manner, reserving the other diagnostic methods for cases in which diagnostic complementation is necessary.
Clinical and epidemiological profile of children and adolescents with hemophilia in a reference center
Authors: Marques Marcela
Published: September 2023

ABSTRACT Objective: To identify clinical and epidemiological data of children and adolescents with hemophilia followed at the Center for Hematology and Hemotherapy of Piaui, characterizing them in terms of age, place of residence, type, severity, main complications, use of prophylaxis and adherence to follow-up. Method: Descriptive, observational and cross-sectional study, using data extracted from the medical records of 63 patients under 18 years of age. The results obtained were analyzed using absolute and relative frequency, in addition to the chi-square test (x2 ). Results: Among 63 patients, 95% had type A hemophilia, 67% had the severe form, and 59% were aged between 11 and 18 years. The presence of complications was associated with a greater number of visits per year. These predominated in the form of chronic arthropathy (37%), while intracranial hemorrhage (ICH) affected 6% of patients. In patients with indication for prophylaxis, 7% did not do it. Among the 05 patients with severe hemophilia who attended 01 visit per year, 80% were from the inland cities and 20% from another state. Conclusions: The clinical and epidemiological characterization of children and adolescents in this specialized reference center corroborates the data available in the literature. HEADINGS: Hemophilia A. Hemophilia B. Blood Coagulation Factors. Epidemiology
Palliative extubation: an experience of four cases in a neonatal intensive care unit
Authors: Guerreiro Beatriz , Leite Fernanda , Prette Iasmin , Venturin Jaqueline , Dias Daneila
Published: September 2023

Objective: Characterize and describe neonatal patients with severe and irreversible conditions undergoing palliative extubation in a neonatal intensive care unit . Case description: Descriptive analysis of four cases of palliative extubation in a neonatal intensive care unit of a childrens hospital in the year 2019 to 2020 based on a review of electronic medical records of the following data: age, primary diagnosis, period of intubation, time of life between extubation and death, symptoms described in the time interval between extubation and death and comfort measures taken, family approach, diagnosis and previous or not follow-up with the palliative care team. All diseases into the exclusive palliative care classification. All patients died after the palliative extubation. The approach of the palliative care team was based on providing comfort measures for the patient, support for the family and the staff of the neonatal intensive care unit. Conclusion: The need for knowledge and deepening of the practice of palliative extubation is essential to make the end of life a time free of suffering, valuing respect and dignity for patients.
EVALUATION OF PEDIATRICIANS' AND NEONATOLOGISTS' KNOWLEDGE ABOUT OCULAR DISORDERS IN CHILDHOOD
Authors: Silva Julia , Foschini Rosalia , Paula Jayter , Silva Marcelo
Published: September 2023

Objective: The aim was to evaluate the level of knowledge of pediatricians and neonatologists about eye problems in children, their diagnosis and management, using a standardized questionnaire. Methods: A questionnaire with demographic data and questions about ophthalmological knowledge was applied among pediatricians, through the transmission line of the pediatric service of the HC FMRP/USP from January to June 2021. A cross-sectional study was carried out, whose responses were tabulated, and statistical analysis was performed using the Krukal Wallis Test and Fishers Exact Test for comparison between the pre-established groups (pediatric residents, 4 to 9 years, and more than 10 years of practice in pediatrics). Sampling was by convenience. Results: The structured questionnaire was sent to 277 pediatricians. Ninety pediatricians answered the questionnaire and 81.11% were female. As for the time of pediatric practice, 42.22% had more than 10 years. From the 17 questions about ophthalmologic knowledge, correct answers ranged from 6 to 14, and the average score was 58.52%. The questions with the highest error rate were about the management of newborns with ocular discharge and congenital tear obstruction and when a premature child should be evaluated by an ophthalmologist. However, no significant differences were found when comparing the correct answers between the groups (p=0.425) Conclusion: The results suggest a deficiency in ophthalmologic knowledge among the pediatricians interviewed; therefore, continuing education and collaboration programs between ophthalmology and pediatrics disciplines should be developed and reinforced to deepen knowledge on these topics.
Epidemiology of prematurity and related comorbidities in very low birth weight preterm newborns
Authors: Gmack Juliana , Ramos João Victor , Venzon Paulyne , Silva Regina
Published: September 2023

Objective: To describe the major epidemiological features of prematurity, risk factors, prevalence of comorbidities, death and survival rates in very low birth weight newborns. Methods: Transversal study with rectrospective data collection from medical charts of 616 premature and very low birth weight newborns admitted to Complexo Hospital de Clínicas da UFPR (CHC-UFPR) between August 2008 and August 2018. It was studied comorbidities prevalence, survival rate and factors related to mortality. For all statistical tests, it was considered a 5% level of significance. Results: The average gestational age (GA) was 28.2 ± 2.9 weeks and the average birth weight (BW) was 997.4 ± 279.9 grams. The population with GA < 28 weeks (42.5%) had a greater need for neonatal resuscitation and ventilatory support and a higher prevalence of the following diseases: respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), pulmonary hypertension, pulmonary hemorrhage, peri-intraventricular hemorrhage (PIVH), retinopathy of prematurity (ROP), patent ductus arteriosus (PDA) and early-onset neonatal sepsis. The main comorbidities associated with an increased risk of death were (p <0.05): RDS (OR: 4,04), pulmonary hemorrhage (OR: 5,21) and PIVH (OR: 3,32). The reduction in survival rate was associated with lower values ??of GA and BW, as well as the presence of respiratory and neurological comorbidities. Conclusions: Extremely premature newborns have a higher prevalence of comorbidities and neonatal complications. Low birth weight, morbidities of the respiratory and neurological systems were the main factors associated with increased mortality.
Synthesis of Nd - Glutamate complex for Paris polyphylla Smith stimulant application
Authors: The Do Minh
Published: September 2023

Nd(HGlu)3.3H2O complexes were successfully synthesized using Nd(NO3)3 and acid glutamic precursors. Effects of acid glutamic concentration, preparation times and Nd/acid glutamic ratios on the reaction performance and the structure of the complexes were investigated. These fabricated complexes have been characterized by infrared spectroscopy (IR), thermal analysis (TGA) and mass spectrometry (MS). The obtained results showed that Nd[H2Glu]2.3H2O complex improved the growth of Paris polyphylla Smith as compared to the control sample.
Implementasi Random Forest Menggunakan SMOTE untuk Analisis Sentimen Ulasan Aplikasi Sister for Students UNEJ
Authors: Anjani Anisa Fitri , Anggraeni Dian , Tirta I Made
Published: September 2023

Pendidikan di era digital sangat memanfaatkan teknologi dan informasi sebagai prasarana  pembelajaran melalui aplikasi milik perguruan tinggi tertenu. Sister for Students (SFS) merupakan aplikasi yang dikembangkan oleh UPT-TIK Universitas Jember yang memiliki peran sangat penting untuk menunjang kegiatan pembelajaran di Universitas Jember, sehingga perlu dilakukan analisis kualitas layanan aplikasi tersebut berdasarkan komentar oleh pengguna menggunakan analisis sentimen. Analisis sentimen merupakan klasifikasi teks yang dilakukan dengan tujuan memperoleh informasi dari pengguna mengenai kualitas layanan SFS. Masalah yang sering terjadi pada proses klasifikasi yaitu adanya data imbalance, salah satunya pada klasifikasi teks. SMOTE dilakukan untuk menangani data imbalance dengan cara membangkitkan data sintetis pada kelas minoritas, hal ini diharapkan agar kinerja klasifikasi lebih baik. Penelitian ini menggunakan metode klasifikasi Random Forest dan SMOTE dengan perbandingan proporsi splitting data  dan  untuk analisis sentimen pada ulasan aplikasi SFS. Data yang digunakan sebanyak 913 data dimana kelas positif sejumlah 363 dan negatif sejumlah 550. Hasil model terbaik yaitu model Random Forest menggunakan SMOTE dengan proporsi 90:10 dengan akurasi testing 98,9%, recall 100%, precision 96,7%, f1-score 98,3% dan nilai AUC sebesar 99,2%. Informasi yang diperoleh dari analisis sentimen SFS UNEJ diperoleh kata yang mengarah positif  yaitu “bagus”, “mantap”, “keren”, “bantu”, “lumayan”, “lebihbaik”, “mudah”, “unej” dan “suka”. Kata yang mengarah pada sentimen negatif yaitu “eror”, “tidakbisa”, “presensi”, “jelek”, “update”, “ribet”, “sulit”, “forceclose” dan “qrcode”.
PERCEPÇÃO DO RISCO DE INFECÇÃO PELA COVID-19 E SEU RELACIONAMENTO COM A PERCEPÇÃO DE CROWDING, SATISFAÇÃO E INTENÇÃO DE COMPRA DE CONSUMIDORES DE SUPERMERCADO
Authors: Silva Julio Cezar Martins da , Oliveira Alessandro Silva de , Silva Ana Paula Martins
Published: September 2023

Com o surgimento da pandemia do COVID-19 o comportamento do consumidor passou por transformações. Da mesma forma, o setor supermercadista passou por novos desafios impostos pela disseminação do vírus. Assim, o objetivo desse artigo é explorar e descrever como os consumidores que frequentam os supermercados percebem o risco de infecção pela COVID-19 e como este se relaciona com a percepção de Crowding humana e espacial, com a satisfação e intenção de compra. A pesquisa é de natureza descritiva e quantitativa contendo uma amostragem não probabilística por conveniência. Foi realizado uma survey caracterizada pela utilização de um questionário online. A condução desse trabalho se justifica, principalmente, pela escassez de pesquisas que estudaram a percepção de risco de infecção pela COVID-19 em um contexto de comportamento do consumidor em supermercado. Dentre os principais resultados, a pesquisa demonstra que, independentemente de um grupo de pessoas terem altos níveis de percepção de risco de infecção pela COVID-19 e de alta percepção de Crowding, elas se mantem altamente satisfeitas e com intenção de compra dos supermercados locais.
MODELOS DE INTELIGÊNCIA ARTIFICIAL NA GESTÃO DE CONSÓRCIOS INTERMUNICIPAIS BRASILEIROS
Authors: Zancan Claudio , Passador João Luiz , Passador Cláudia Souza
Published: September 2023

O objetivo principal deste artigo é propor o uso de modelos de inteligência artificial na gestão de consórcios intermunicipais no Brasil, com implementação de ferramentas tecnológicas que permitem, de forma coordenada e estratégica, a gestão eficiente dos serviços de água, esgoto, segurança e transporte público. Essa discussão ganha importância por vários motivos, entre os quais a melhoria na tomada de decisões é um deles, fornecendo diretrizes capazes de tornar o processo de tomada de decisões mais informado e preciso. Assim, o conceito de consórcios intermunicipais, inteligência artificial e variantes, são explorados como pressupostos teóricos, concebendo um estudo qualitativo, com características descritivas e propositivas. Concluiu-se que a utilização da inteligência artificial para a gestão de consórcios de serviços intermunicipais é percebida como uma abordagem promissora e inovadora, otimizando processos, melhorando a eficiência operacional, reduzindo custos e aumentando a qualidade dos serviços oferecidos à população. Como estudos futuros são considerados aspectos que envolvem a avaliação de desempenho, estudos de viabilidade econômica, avaliação de impactos sociais e ambientais, aspectos éticos e legais, bem como os que envolvem a adoção de novas tecnologias na exploração do uso de outras técnicas e abordagens, como a computação em nuvem, a internet das coisas (IoT) e o blockchain.
Predictive value of WBC differential on different clinical variables& scAR formation in Chickenpox (variceila)
Authors: M Al-Kumait Thikraa , A. Abd Saifeldeen , D' Moohy Alosy Baha
Published: September 2023

This prospective study was executed over a period of 5 year from February 2003 to December 2007 in the central pediatric hospital & 5 primary health care center in Baghdad then in the Tikrit hospital & trvo private clinic in Tikrit, one handered trventy (120) children lvith chickenpox were enrolled in this study' By 95% cl Pairecl sanrples Test effect oi wBC courlt on different clinical variables & scAR formation' The result indicate that Rash usual site lvas commonest & safest type of milderdisease (l15 =%96)while Rash unusual site give us pointer to predict the moderate course of disease &it rvas documented for first time in our study only, Hyper pigmented area can be safest type of discoloration happcned in course of diseasc .llcmorrhagic Rash0.2g7 gives predictive indicator for serious type of aggrcssivc picturc of chickenpox
Linguacultural prerequisites for the creation of new lexical units in dystopias (on the example of the lexical-thematic group "Names of socio-political organizations" in George Orwell's dystopian novel "1984")
Authors: Studenikina Daria Georgievna
Published: September 2023

This research studies the mechanisms of the formation of the author's vocabulary in the text of a dystopia. This vocabulary is called non-existent designations of literary reality. Extra linguistic factors influence the formation of the author's neologism. One of the factors is culture, which influenced the formation of linguistic consciousness. A literary work is a space in which the linguistic embodiment of the author's image of the world, his linguistic culture is concentrated. The material of the research is the text of the dystopian novel "1984" by George Orwell. Dystopia is of interest as one of the fantastic subgenres. The structure of the dystopian world is constructed on the author's fantasy, demonstrating non-existent things. Non-existent denotations are named according to this genre specificity. In the composition of the novel, the depiction of contradictions in the life of society and an undesirable political system is significant for building the world. In this regard, the purpose of the study is to describe the lexical-thematic group "Names of socio-political organizations" in George Orwell's dystopian novel "1984" and to identify productive elements for creating the vocabulary of this group. The paper uses the descriptive method used in the onomasiological approach. As a result of the research, the units that make up the lexical-thematic group "Names of socio-political organizations" were selected, productive elements for creating the studied names were identified, and their lexical meaning was characterized. It can also be concluded that the text of a dystopia is the space in which the author's imagination is realized when creating a non-existent world. This world is not a copy of objective reality. At the same time, the naming of fragments of the new reality is based on the knowledge contained in the mind of the author.
Research of the problems of subjectivity development in the digital environment
Authors: Bogdanova Veronika Olegovna
Published: September 2023

The article presents the results of a focused interview to identify problematic markers of the development of the structural components of subjectivity in the younger generation. The object of the study is the manifestation of the subjectivity of the younger generation in the Internet space. The subject of the study is the problematic markers of the development of youth subjectness in the digital environment. The theoretical significance and novelty of the study lies in the systematization of theoretical ideas about the influence of the digital environment on the development of subjectivity. The practical significance lies in identifying problematic markers for the development of subjectivity in the digital environment, knowledge of which can be used to create a person-centered educational environment. Empirically, the main problematic markers of the development of some structural components of subjectness were identified: individuality, reflection and empathy. The ratio of freedom and responsibility in the digital environment is determined from the point of view of representatives of the younger generation. The results of this study can be used to develop psychological and pedagogical programs aimed at developing the skills of reflection, self-determination, self-realization, emotional regulation, positive self-attitude and empathy.
The Ethical Thought of the Bengal Renaissance:A Discovery of Morality in Indian Tradition (1815–1870)
Authors: Skorokhodova Tatiana G.
Published: September 2023

The origin of Modern Indian ethical thought is described in the article. The author depicts the genesis of ethics as originated from the works by key personalities of the Bengal Renaissance XIX – early XX century. The juxtaposition with traditional Indian thought permits to present the intellectual process in Modern Bengal elite minds as ‘discovery of morality’. Based on hermeneutic analysis of the texts on moral problematics from Rammohun Roy and the Brahmo Samaj thinkers to Krishnamohun Banerjea, the author reconstructs the becoming of Indian ethical thought in the context of their striving for the moral regeneration of traditional society. For the first time the genesis and becoming of thinking of Indian intellectuals about morality in its connections with the present condition of social decline in colonial India are disclosed in the research. The experience of Bengal thinkers of 1815–1870th demonstrates the solution of super-task to find ethics in ancient sacred texts and next to build religiously based ethics. The super-task had been settled by the method of interpretation that permits to see high moral precepts in high faith in One God of original religion as it opposed to polytheistic Hinduism. The result of applying the method was embodied in the creative and high conception of Hindu morality based on ethical God Creator. The Bengal thinkers are firmly convinced that displaced into periphery of Hindus’ consciousness morality as a code of normative ethics must be revived and turned into leading imperatives of consciousness of people.