bluuebunny/crossref_metadata_2025 huggingface dataset:
Geometric identification of dynamic objects on image sequences
Authors: Dashkevych Andrii
Published: October 2023

As a result of the work, an approach to fast identification of dynamic objects described as points in metric spaces has been developed, the identification process is based on the assumption of the proximity of points corresponding to different states of the same object in a given metric space. The presented approach is based on the comparison of distances between points describing the state of the object. The results of the work are implemented in the form of software for the identification of dynamic objects on sequences of digital images and visualization of such experiments. The approach was tested on synthetic data and on real data for the identification of objects found in the video. Figs.: 4. Refs.: 12 titles.
Application of the method of analysis of hierarchies for the selection of the optimal model of consolidation of IT resources of the SFD of Ukraine
Authors: Ilin Serhii , Kholod Ievgenii , Maznychko Andrij , Horodnycha Lubov
Published: October 2023

The selection of the optimal technology for the consolidation of information resources from the information support of the State Register of Documents of the Documentation Insurance Fund of Ukraine was carried out among technologies IaaS, PaaS, SaaS, DaaS, web applications, etc.

This multi-criteria problem with a large number of factors of different dimensions was solved using the method of analysis of hierarchies. Figs.:1. Tabl.:  2, Refs.: 15 titles.
Using quadratic Volterra model of the oculo-motor system in diagnostic research of psychophysiological state of human
Authors: Pavlenko Vitaliy , Shamanina Tetiana , Chori Vladyslav
Published: October 2023

It contains the results of the study of the effectiveness of the application of approximation Volterra models of the first and second order of the oculo-motor system in diagnostic studies of the psychophysiological state of a person based on eye-tracking data. Visual stimuli are used as test signals, which are displayed on the monitor screen at different distances from the initial position, which formally corresponds to the action of step signals with different amplitudes at the OMS input. Experimental studies of the "input-output" of the OMS were carried out using the Tobii Pro TX300 eyetracker, and the first-order transient functions and the second-order diagonal intersections of the second-order transient functions were determined based on the eye-tracking data. The resulting transient functions are used to form the spaces of diagnostic features. The diagnostic value of all possible combinations of features in pairs according to the indicator of the probability of correct recognition (PCR) was studied. The research results were obtained using Bayesian classifier training in different spaces of the proposed features. A study of the robustness of features according to the PCR indicator was carried out, the combinations of features with the maximum and most stable PCR indicator were selected. Figs.: 13. Tabl.: 5. Refs.: 28 titles.
Internal ballistics of the arrow-bow system in the transverse plane
Authors: Zanevskyy Ihor , Zanevska Lyudmyla
Published: October 2023

A mechanical-mathematical model of the arrow-bow system has been developed, taking into account the longitudinal dynamic bending of the arrow in the transverse plane. The method of studying the system in the form of Lagrange equations of the second kind, constructed on the basis of Hamilton’s variation principle, was applied. The natural frequencies and Eigen functions were determined using a modified Newtonian method with use of Feodosiev series. Il.: 3. Bibliogr.: 23 items.
Force Multiplier: A Critical Reflection on Developing a Public Archaeology Veterans Program in Underwater Archaeology
Authors: McKinnon Jennifer F. , Ticknor Anne , Scott-Ireton Della
Published: October 2023

In 2018, East Carolina University’s (ECU) Program in Maritime Studies, in partnership with the Florida Public Archaeology Network (FPAN) and veterans’ nonprofit Task Force Dagger Special Forces Foundation (TFDF), developed and undertook an underwater archaeology veterans program on WWII-related submerged sites in Saipan, Commonwealth of the Northern Mariana Islands (CNMI). This program was called the Joint Recovery Team (JRT) and consisted of retired and medically retired Special Operations Forces (SOF) veterans from across the United States armed forces (i.e., Army, Navy, Marines, Air Force). The project included training 14 veterans in archaeological techniques and an intensive 2-week investigative field project, during which veterans assisted with archaeological target testing, site identification, and recording. A National Park Service (NPS) Maritime Heritage Program grant supported the training and the Department of Defense, Defense Prisoner of War/Missing in Action Accounting Agency (DPAA) financially supported the field project. Project leadership undertook training assessments including a program survey, field observations, unstructured interviews, and reflection journals. This article outlines the development of the public archaeology program, training, fieldwork, and assessments and provides a critical reflection of successes and areas for improvement.
Selection Criteria for Repurposing Oil And Gas Well to Geothermal Heat Extraction
Authors: Merzoug Ahmed , Okoroafor Rita Esuru
Published: October 2023

Oil and gas wells are generally plugged and abandoned when they reach the end of their economic life. Thus repurposing these wells to harness the geothermal energy was supported as a way to reduce the abandonment expenses for the operators and cheaper access to the deeper formation with high temperatures for a geothermal operator. Oil and gas wells are drilled in different fields with different reservoir properties and well completion. This work is a numerical modeling study to understand the effect of rock properties (reservoir temperature, thickness, permeability, and porosity) on the power generation capacity. This study combines the two major challenges of injectivity and energy production as a ratio to define the major reservoir properties for optimum geothermal system circulation. This work also investigates the different oil and gas well completion (number of casings and their associated depth) on the heat losses in the wellbore for different circulation rates This work can serve as a roadmap for screening wells within a field for better geothermal energy production.
Distinct ossification trade-offs illuminate the shoulder girdle reconfiguration at the water-to-land transition.
Authors: Nakamura Tetsuya , Wei Janet , Wood Thomas , Flaherty Kathleen , Fitch Olivia , Enny Alyssa , Andrescavage Ali , Brazer Danielle , Navon Dina , Cohen Hannah , Shanabag Anusha , Kuroda Shunya , Stewart Thomas , Braasch Ingo
Published: October 2023

The mechanisms of the pectoral girdle transformation at the origin of terrestrial locomotion in vertebrates remains an outstanding problem in evolutionary biology. 1. The loss of dermal bones and the enlargement of endochondral bones resulted in the disarticulation of the pectoral girdle from the skull and the formation of the neck during the fish-to-tetrapod transition2-5. Despite the functional implications of this skeletal shift in the emergence of terrestrial vertebrates, the underlying genetic-developmental alterations have remained enigmatic. Here, we discovered that in zebrafish pectoral girdle mesodermal cells expressing gli3, a transcription factor in the Hedgehog signaling pathway, contribute to both dermal and endochondral bones. We show that Gli3 regulates expression of activin A receptor type 1-like, a BMP type 1 receptor lost in tetrapod lineages, and thereby determines endochondral and dermal ossification. Intriguingly, Gli and Hedgehog compound knockout fish exhibited an unexpected combination of actinopterygian fish and stem-tetrapod pectoral girdle characteristics. These ontogenetic and anatomical data suggest that a trade-off between the two distinct ossification pathways is a deeply embedded developmental program in bony fishes, with potential for tuning of this trade-off to generate novel pectoral girdle forms akin to stem-tetrapods at the dawn of vertebrate terrestrialization.
Structural alignment: the link between diversity, specialization and development
Authors: Gisbert Oriol
Published: October 2023

This paper examines the relationship between diversity, specialization, and economic development by analysing various indicators applied to country exports data. Indicators of concentration reveal a non-linear relationship between diversity and income, suggesting a tendency to re-specialize at high income levels. Similar conclusions are drawn when considering the count of product specializations (RCA). On the contrary, economic complexity indices which incorporate information about countries’ diversity and products’ ubiquity, exhibit an exponential relationship with income. However, the challenge lies in associating the value of economic complexity with the underlying structure of a country. Using the Kullback-Leibler divergence, we show that economic development is associated with increasing alignment between a country's export structure and the share of goods in global demand. This alignment is achieved through specialization in central natural resources or through industrialization, which increases diversity. Finally, we show that industrialization is preferable as it promotes high alignment with global demand across all categories of goods.
Unveiling the Role of Teachers’ Self-Efficacy in Improving Job Happiness: Insights from Student and Parent Perspectives
Authors: Li Ying , Yang Fan , Hu Zhanshuo , Qi Zhanyong
Published: October 2023

Teachers' self-efficacy is closely associated with student and parent satisfaction, and the quality of school education directly affects parental satisfaction. This study aims to investigate the interplay between teachers’ self-efficacy, student satisfaction, and parental satisfaction in a specific city in China. Online questionnaires were utilized to gather data for analysis, aiming to enhance the quality of regional basic education through a comprehensive understanding of this tripartite relationship. The findings highlight the pivotal role of self-efficacy in improving teachers' job happiness, which is influenced by students' satisfaction and parental satisfaction. Factors such as teachers' academic level, learning background, and job satisfaction contribute to the development and augmentation of self-efficacy.
IL-17 Signaling in Primary Sclerosing Cholangitis Patient-Derived Organoids
Authors: Moreno Ana Sofia Garcia , Guicciardi Maria Eugenia , Wixom Alexander Q. , Jessen Erik , Yang Jingchun , Ilyas Sumera I. , Bianchi Jackie K. , Vairo Filippo Pinto e , Lazaridis Konstantinos N. , Gores Gregory J.
Published: October 2023

The pathogenesis of primary sclerosing cholangitis (PSC) is unclear, although studies implicate IL-17A as an inflammatory mediator in this disease. However, a direct assessment of IL-17 signaling in PSC cholangiocytes is lacking. In this study we aimed to investigate the response of PSC extrahepatic cholangiocyte organoids (ECO) to IL-17A stimulation. Cholangiocytes obtained from PSC and non-PSC patients by endoscopic retrograde cholangiography (ERC) were cultured as ECO. The ECO were treated with vehicle or IL-17A and assessed by transcriptomics, secretome analysis, and genome sequencing (GS). Unsupervised clustering of all integrated scRNA-seq data identified 8 cholangiocyte clusters which did not differ between PSC and non-PSC ECO. However, PSC ECO cells demonstrated a robust response to IL-17 treatment, noted by an increased number of differentially expressed genes (DEG) by transcriptomics, and more abundant chemokine and cytokine expression and secretion. After rigorous filtering, GS identified candidate somatic variants shared among PSC ECO from unrelated individuals. However, no candidate rare variants in genes regulating the IL-17 pathway were identified, but rare variants regulating the MAPK signaling pathway were present in all PSC ECO. In conclusion, PSC and non-PSC patient derived ECO respond differently to IL-17 stimulation implicating this pathway in the pathogenesis of PSC.
Cytotoxicity and Toxicoproteomic Analysis of Pioglitazone Exposure in Human-derived Cardiomyocytes
Authors: Sultan Abdullah Al , Rattray Zahra , Rattray Nicholas J. W.
Published: October 2023

Pioglitazone (PGZ) is a peroxisome proliferator-activated receptor gamma agonist widely used as an insulin sensitiser agent for type II diabetes mellitus. The heterogeneity of PGZ effects on cardiac tissue has remained controversial, as contradictory data exist in the literature. Nevertheless, a consensus has reported an associated increased risk of heart failure (HF) following chronic systemic exposure to PGZ, which has hampered its clinical use in diabetes management. The mechanism of PGZ-induced HF remains largely uncharacterised. Here, we report a comprehensive in vitro study combining a novel toxico-proteomic pipeline with cytotoxicity assays in human adult cardiomyocytes to elucidate mechanistic insights into PGZ cardiotoxicity and identify driver proteins associated with such effects. Cytotoxicity assay findings showed a significant loss of mitochondrial adenosine triphosphate production following PGZ exposure, suggesting that this decline underpins PGZ cardiotoxicity. Interestingly, proteomics analysis revealed that the mitochondrial dysfunction was attributed to PGZ mediating mitochondrial uncoupling and ultimately cardiomyocyte death. The type of cell death was also found to be related to the mitochondria—protein upregulation in the phosphoglycerate mutase family 5–dynamin-related protein 1 axis, suggesting mitochondrial-mediated necroptosis. Furthermore, our analysis suggested the potential activation of the interplay between the complement and coagulation systems and the disruption of the cytoskeletal architecture, which was primarily mediated through integrin-signalling pathways, responsible for PGZ-induced myocardial contractile failure. Collectively, our findings provide substantial mechanistic insight into PGZ adverse effects and may eventually provide the rationale for future optimisation of antidiabetic therapies. (239 words)
Photo-luminochromism of organic crystals arising from subtle molecular rearrangement
Authors: Yuan Wang Zhang , Zhao Zihao , Cai Yusong , Zhang Qiang , Li Anze , Zhu Tianwen , Chen Xiaohong
Published: October 2023

Photo-responsive colour-changing luminescent materials play an increasingly significant role in intelligent applications for their programmability. Nevertheless, current research mainly focuses on photochemical processes, while the photoluminescence (PL) transformation is scarcely accomplished by uniformly adjusting the aggregation mode. Here we show an impressive photo-luminochromism phenomenon from organic crystals (e.g. dimethyl terephthalate crystals) with PL varying from dark blue to purple and then to bright orange. This change is attributed to the subtle molecular rearrangement prompted by light irradiation. The through-space π-π interactions and moderate short contacts between ester groups are vital to enable this process. Furthermore, while the irradiated crystals own outstanding stability, the PL transformation is reversible with sufficient relaxation. These materials show promising applications in information storage and smart optoelectronic devices. These findings provide a new venue to the construction of smart photo-luminochromic materials with remarkable PL colour changes through molecular rearrangement.
Comparative Results of Triple Arthrodesis for the Management of Stage III Posterior Tibial Tendon Dysfunction between Rheumatoid and Non-Rheumatoid Patients
Authors: Demirel Mehmet , Şentürk Fatih , Mert Lezgin , Koyuncu Dağhan , Ersin Mehmet , Altan Murat , Kılıcoğlu Onder Ismet
Published: October 2023

Objective
Although the recommended treatment for stage III posterior tibial tendon dysfunction (PTTD) is triple joint complex fusion, the literature is limited on this topic. No study has specifically investigated the influence of rheumatoid arthritis (RA) on the outcomes of triple arthrodesis. This study aimed (1) to report mid-to-long-term results of triple arthrodesis for stage III PTTD and (2) to investigate the difference in the results of triple arthrodesis between rheumatoid and nonrheumatoid patients.
Methods
Thirty feet of 25 patients (16 females, 9 males; mean age 53, (39-71)) with stage III PTTD who were treated by triple arthrodesis were retrospectively analyzed. The mean follow-up was 82 (28 – 144) months. Patients were divided into two groups based on etiology: group ID (idiopathic PTTD) and group RA (PTTD secondary to RA). All clinical and radiographic outcomes were compared. The mean American Orthopedic Foot and Ankle Society (AOFAS) score was measured preoperatively and at the final follow-up. The 36-Item Short Form Survey (SF-36) and visual analog scale (VAS) were measured at the final follow-up.
Results
The mean AOFAS score improved from 57±6.81 (46–68) and 49±14.66 (18–79) preoperatively to 82±15.57 (44–94) and 77±14.46 (48–94) in group ID and group RA, respectively, with no significant difference between thepre- and postoperative values between the groups (p <.001). The mean VAS score at rest was 0.45±0.68 (0–2) in group ID and 1±1.08 (0–3) in group RA (p =.23). There was no significant difference in any SF-36 domain(p >.05) except for physical health, which was lower in the RA group (p =.002).
Conclusion
Although rheumatoid patients present with radiographically more severe flatfoot deformity, triple arthrodesis can provide similar satisfactory clinical and radiological outcomes with a low complication rate for stage III PTTD in rheumatoid patients as much as nonrheumatoid patients in long-term follow-up.
Level of Evidence: Retrospective cohort study, Level 3 Evidence
WITHDRAWN: Elevated Temperature Effects on Dynamics of Blade Growth and Erosion in Saccharina Latissima (Laminariales)
Authors: Ding Xiaowei , Timmermans Klaas R
Published: October 2023

The dynamics of blade growth and erosion in Saccharina latissima (Laminariales) control the final surface area of blades. The negative effects of elevated temperature on the surface area of blades may result from inhibition of growth and stimulation of erosion, eventually leading to release of carbon (C) and nitrogen (N). In this study, we investigated temperature effects on the growth and erosion of S. latissima blades incubated at ambient and elevated temperatures. For the first time, to our knowledge, growth rates of the meristem and total blade and the erosion rate of the distal blades were quantified simultaneously. Additionally, by analyzing the C and N content along with erosion rate, we could calculate the potential release of C and N to seawater. The results show a significant decrease in the relative growth rate and a significant increase in the erosion rate of the distal ends of blades when the temperature reached 23 ˚C. Results of the C and N analyses show that S. latissima released almost twice as much C and N at elevated temperatures than at ambient temperatures.
The primary porosity heterogeneity characteristics of braided river sandbody and implications for predicting the current physical properties heterogeneities
Authors: Yiming Yan , Zhang Liqiang , Xiaorong Luo
Published: October 2023

Understanding the heterogeneity of reservoirs is crucial for enhancing the efficiency of hydrocarbon exploration and development. The primary porosity of samples from modern braided river sands and outcrops of braided river sandstone was calculated using a model previously proposed by the authors. The characteristic parameters (Vx) for calculating primary porosity are closely related to the architectural-elemental configurations (AEC), and the AEC of braided river sand bodies (BRSD) has apparent effects on the distribution of the primary porosity heterogeneities. Analysis of our results has established a simple primary porosity heterogeneity model of BRSD. The center of braided river channel and mid-channel bars have excellent strong primary petrophysical properties with high primary porosity exceeding 38%. The contact areas between the braided river channel and channel bars exhibit relatively low primary porosities of less than 33%. The area between the center and edge of the braided bars and channels displays medium primary porosities. The nonlinear correlation in the Q-Q plot of the primary porosity and present porosity of samples from BRSD in the Ahe Formation is mainly caused by chemical diagenesis. The present porosity heterogeneity of BRSD in the Ahe Formation is less influenced by compaction and cementation, it predominantly arises from the differential of dissolution. Q-Q plots attempt to correlate the geological information from an individual sample with the heterogeneity of present porosity in BRSD. In addition, by utilizing Q-Q plots of the primary and current petrophysical properties of the sand body, the relative extent of heterogeneity modification caused by different diagenetic processes can be assessed. This assessment is crucial for modeling macroscopic models of physical properties during geological history periods.
Investigate the post-grouting bearing property of drilled piles in heavily weathered mudstone strata based on the O-cell test method
Authors: Ou Xiaoduo , Sang Runhui , Bai Lu , Jiang Jie
Published: October 2023

The study focuses on analyzing the bearing capacity of six cast-in-place drilled piles located in three distinct portions of the urban square at Ronghe East Station in Nanning was evaluated through static load testing using the Osterberg cell (O-cell) method, and the bearing deformation characteristics of post-grouting piles in heavily weathered mudstone stratum were analyzed. By fitting the resistance and relative displacement curves at the pile end and side, a load-settlement calculation method for post-grouting piles in a heavily weathered mudstone stratum was established by adopting the hyperbolic load transfer model, which has the tip hardening and the side softening. The accuracy of the method was verified through actual engineering test pile modeling and changed post-grouting piles' diameter and length to further examine their bearing properties. The bearing capacity exhibits a progressive increase with an increase in either the length or diameter of the pile. However, an effective length exists when the pile length is increased to increase the bearing capacity. The use of combined grouting technology can achieve a significant increase in bearing capacity, up to approximately 1.3 times, which can realize the economy and high efficiency of improving the bearing performance of pile foundations.
CoS2/V2O3 heterostructure with coffee ground derived carbon as superior composite anodes of sodium-ion batteries
Authors: Xue Yongqi , Wu Jun , Cheng Zhiqun , Xu Congxin , Cai Yurong , Ni Wenbin , Zhou Xiaochong
Published: October 2023

The poor ion transport kinetics and serious volumetric change of transition metal sulfides hinder their electrochemical applications. In this study, we introduced a heterostructure between CoS2 and V2O3 as an anode of sodium-ion batteries (SIBs) via a feasible hydrothermal method combining with a biomass carbon derived from coffee grounds (CG). The as-prepared CoS2/V2O3-CG composite retained a reversible capacity of 464.5 mAh g-1 after 300 cycles at 0.5 A g-1, exhibited an excellent rate capability of up to 8 A g-1 and a remarkable long-cycling life of over 2,000 cycles at 2 A g-1 with a capacity decay rate of less than 0.041% per cycle. The kinetic analysis indicated that CoS2/V2O3-CG composite exhibited a superior capacitive behavior, making it a high Na+ diffusion coefficient in SIBs. The enhanced electrochemical performances of composite can be primarily attributed to the CoS2/V2O3 heterostructure and porous biomass-derived carbon, which offers a built-in electric field and a large surface area, and effectively alleviates the volumetric expansion effect.
A novel aging-associated lncRNA prognostic signature for predicting immunotherapy and chemotherapy response in pancreatic cancer
Authors: Li Yan , Chen Yuling , Li Bo , Zheng Guoxing , Zang Chuanbing , Zhu Qingqing , Zhu Chengming , Ye Yuanchun
Published: October 2023

Background: Tumors commonly develop as individuals age, and their relationship is intricately connected yet remarkably unclear). On one hand, long non-coding RNAs (lncRNAs) affect the proliferation, invasion, metastasis, prognosis, and drug resistance of most tumors, including pancreatic cancer. On the other hand, increasing evidence suggests that lncRNAs are also widely involved in the aging process. Nevertheless, it remains unknown whether aging-associated lncRNAs impact the prognosis and immune microenvironment of pancreatic cancer.
Methods: Transcriptomic and clinical information of pancreatic cancer were obtained from TCGA databases. Aging-associated lncRNAs were enriched by co-expression analysis based on 500 aging-related genes in Aging Atlas database. Then aging-associated lncRNAs signature risk model was constructed by univariate, multivariate and Lasso Cox regression analysis. The receiver operating characteristic (ROC) curve, Kaplan-Meier analysis and nomogram were performed to evaluate the prognosis value and predictive ability. Patients in the PACA_PU databases were enrolled to verify the risk model as an external validation. ESTIMATE, single-sample gene set enrichment analysis (ssGSEA) and TIDE were used to analyze the immune microenvironment and immunotherapy response. And drug sensitivities were analyzed with the pRRophetic algorithm.
Results: A risk signature containing six aging-associated lncRNAs (RP11-731F5.2, PVT1, RP1-239B22.5, LINC01004, RP11-61J19.5 and RP11-132A1.4) was established and shown to be significantly associated with overall survival in pancreatic cancer patients. The ROC curve, nomogram and PCA analysis demonstrated the accuracy and stability of the risk model’s ability to predict prognosis as well as its good clinical utility. The ESTIMATE and ssGSEA results suggested a strong relationship between the aging-associated lncRNAs risk signature and immune infiltration of pancreatic cancer. The analysis of PD1, TIDE, TMB and MSI further demonstrated the effectiveness of this risk signature for predicting immunotherapy response. In addition, this risk signature was also useful for predicting the sensitivity of chemotherapeutic agents.
Conclusion: We constructed a novel aging-associated lncRNAs-derived risk signature with good prognostic value in pancreatic cancer that effectively predicted immunotherapy response and chemotherapeutic drug sensitivity.
Flexible, stretchable, and highly sensitive piezoresistive strain sensors based on modified PEDOT:PSS layers with nickel microparticles
Authors: Ramadan Rehab , Martín-Palma Raúl J.
Published: October 2023

Here, we describe the development and fabrication of a flexible, stretchable, and conductive piezoresistive strain sensor based on poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS). This sensor, which can detect small strains, shows a remarkable sensitivity due to the presence of a layer of interconnected Ni microparticles (NiMPs) on its surface. Furthermore, polyvinyl alcohol (PVA) was used as a matrix to improve the elasticity of the conducting PEDOT:PSS membrane. Accordingly, a piezoresistive strain sensor composed of PEDOT:PSS, PVA and a layer of NiMPs (PEDOT:PSS/PVA/NiMPs) was fabricated and its electrical signal, stability and response time were studied at different strains and bending angles. NiMPs were stuck on the conducting polymer and distributed uniformly by a very simple and costless method using a magnetic stirring bar magnet. The applied strains varied from 0–28%, which is the typical range of human body movements (arms, fingers, knees, and feet, facial expressions and breathing rate). The experimental results show an outstanding performance of the sensors compared with other strain sensors based on PEDOT:PSS.
A self-adaptive viscosity-type inertial extragradient algorithm for solving monotone variational inequality and paramonotone equilibrium problem 1
Authors: Huang Xiaoqing , Zhao Yali , Zhao Ziru
Published: October 2023

In this paper, we introduce a self-adaptive viscosity-type inertial extragradient algorithm to solve monotone variational inequality problem and paramonotone equilibrium problem in real Hilbert space. Based on the self-adaptive method, inertial technique is used to accelerate the convergence rate of the method. Under the assumption of monotonicity of the related mappings, the strong convergence of the iterative algorithm is established. The results presented here improve and generalize many existing results in this direction. Mathmatical subject classification: Primary: 90C33; Secondary: 49J52
Claimant and clinician perspectives on sources of claimant distress in interactions with Australian compensation schemes: A qualitative study
Authors: Sim Alison , McNeilage Amy G. , Ashton-James Claire E.
Published: October 2023

Purpose
Recovering from compensable injuries can be influenced by a variety of factors including the claimant’s experience of distress during the claims process. In order to develop cross-scheme, nation-wide strategies to improve claimants’ interactions with the compensation system, reduce claimant distress, and improve claimant outcomes, it is important to understand sources of claims-related distress from the perspective of both claimants and clinicians.
Methods
Semi-structured interviews with 13 claimants and 26 clinicians from four injury compensation schemes in five Australian states were conducted. A collaborative and reflexive thematic analysis was undertaken with an inductive approach to coding, and themes were constructed for claimants and clinicians across compensation schemes.
Results
Claimants and clinicians interviews revealed four main sources of distress, including (1) complexity and delays in administrative processes, (2) interruptions to recovery caused by treatment delays, (3) standardised approaches to care, and (4) a lack of support for navigating the claims process.
Conclusion
Sources of claims-related distress identified by claimants and clinicians in the present study are consistent with previous quantitative and qualitative studies published over the past 20 years, pointing to the urgent need for nationwide systems level changes to reduce claimant distress in the pursuit of better claimant outcomes.
Synthesis and characterization of (E)-4-((anthracen-9-ylmethylene) amino)-N- (pyridin-2-yl) benzenesulfonamide and its metal complexes: Evaluation of potential against the colon cancer cell line COLO-205 and biological activity profiles
Authors: Jona P , Suja P S , Suman N. , Robinson S. , Amutha S. , Kumar P. Ram
Published: October 2023

The use of schiff base metal complexes has attracted considerable interest because of their wide-ranging applications in the fields of coordination chemistry and biological sciences. A straightforward simple condensation methodology with acid catalyst approaches was used to synthesize a (E)-4-((anthracen-9-ylmethylene)amino)-N-(pyridin-2-yl) benzenesulfonamide schiff base ligand. The followed by the synthesis of the metal–ligand complexes encompassed the coordination of the Schiff base ligand to the transition metal ion in an ethanolic medium. Subsequent structural characterization and their properties were predicted using spectroscopic and analytical techniques. Furthermore, we evaluated the biological properties exhibited by these complexes, with a specific emphasis on their potential applications as antimicrobial, anticancer, antioxidant, and enzyme inhibition agents. The findings derived from this investigation yield significant perspectives regarding the formulation and advancement of innovative metal– organic complexes that exhibit augmented therapeutic attributes.
SYCL in the Edge: Performance Evaluation for Heterogeneous Acceleration
Authors: Faqir-Rhazoui Youssef , García Carlos
Published: October 2023

Edge computing is essential to handle increasing data volumes and processing capacities. It provides real-time, secure data processing near data sources, like smart devices, alleviating cloud computing energy use and saving network band-width. Specialized accelerators, like GPUs and FPGAs, are vital for low-latency edge computing but the requirements to customized code for different hardware and vendors supposes important compatibility issues. This paper evaluates the potential of SYCL in addressing code portability issues encountered in edge computing. We employed the Polybench suite to compare various SYCL implementations, specifically DPC++ and AdaptiveCpp, with the native solution, CUDA. The disparity between SYCL implementations was negligible, at just 5%.
Furthermore, we evaluated SYCL in the context of specific edge computing applications such as video processing using three different optical flow algorithms. The results exposed a potential performance gap of 19% between CUDA and SYCL. This performance differential is the price one may need to pay when achieving the ability to successfully run the same code on two distinct edge boards with four different architectures, including x86/64 CPU, ARM CPU, NVIDIA GPU, and Intel GPU. These findings underscore SYCL’s capacity to increase productivity in term of development costs and facilitate the IoT deployment without being locked into a particular platform or manufacturer.
Oxytetracycline hyper-production through targeted genome reduction of Streptomyces rimosus
Authors: Petković Hrvoje , Pšeničnik Alen , Slemc Lucija , Avbelj Martina , Tome Miha , Šala Martin , Herron Paul , Shmatkov Maksym , Petek Marko , Baebler Špela , Mrak Peter , Hranueli Daslav , Starcevic Antonio , Hunter Iain S.
Published: October 2023

Most of the biosynthetic gene clusters (BGC) encoding the biosynthesis of important microbial secondary metabolites, such as antibiotics, are either silent or poorly expressed; therefore, robust technologies are required to secure the production of natural products for both drug discovery and any subsequent commercial fermentation processes. Industrial strain improvement has resulted almost exclusively from expensive and time-consuming approaches to strain improvement. Therefore, to ensure a strong pipeline of truly novel antibiotics there is an urgent need to develop rapid and efficient strain improvement approaches. This study uses comparative genome analysis to instruct rational strain improvement, using Streptomyces rimosus for the industrial production of the medically-important antibiotic oxytetracycline. Sequencing of the genomes of two industrial strains M4018 and R6-500, developed independently from a common ancestor, identified large DNA rearrangements located at the terminal parts of the chromosomes that occurred in approximately at the same location in both strains. We evaluated the effect of these DNA deletions at similar locations of the parental S. rimosus Type Strain (ATCC 10970) genome. Surprisingly a single engineering step in the Type Strain (introduction of a 145kb deletion close to the otc BGC) resulted in significant OTC overproduction, achieving titers that were equivalent to the M4018 and R6-500 strains used for the industrial production of OTC. Transcriptome data fully support the hypothesis that the main reason for such an increase in OTC biosynthesis was due to massively enhanced transcription of the otc BGC and not to enhanced substrate supply. Surprisingly, we also observed changes in the expression of other cryptic BGCs. Similarly, some metabolites, previously undetectable in ATCC 10970 were now produced at relatively high titers. This entirely new approach to strain improvement demonstrates great potential as a rapid and versatile technology to increase titer of the target secondary metabolite in a one-step procedure, and to activate cryptic gene clusters, which are an enormous source of yet unexplored natural products of medical and industrial value.
The Nuremberg Chronicle by Hartmann Schedel as a Source for Early Modern History of Reading
Authors: Адамова Н.Э.
Published: October 2023

Статья посвящена восприятию «Книги хроник» (1493) Хартмана Шеделя читателями раннего нового времени. В статье рассматриваются особенности создания «Книги хроник», то, каким видели будущего читателя ее нюрнбергские создатели, а также, кем были реальные владельцы экземпляров книги в Европе раннего нового времени. Наконец, на основе анализа читательских маргиналий конца XV–XVII вв. в ста экземплярах «Книги хроник» из британских, российских и немецких библиотек характеризуются интересы и практики читателей этой книги. Особое внимание уделяется тому, как в условиях Реформации читатели разной конфессиональной принадлежности взаимодействовали с нарративом Шеделя о «сакральной истории».

The paper examines how early modern readers perceived and used the “Nuremberg Chronicle” (1493) by Hartman Schedel. The paper outlines creation of the “Nuremberg Chronicle”, discussing the intentions of its authors, and observes what readers actually possessed the “Nuremberg Chronicle” in early modern Europe. Finally, relying on the early modern readers’ marginalia in more than one hundred copies of the “Nuremberg Chronicle” held by the British, Russian, and German libraries, the paper explores the readers’ interests and reading practices. The paper especially focuses on how the readers of conflicting confessional affiliations interacted with Schedel’s narrative of “sacred history” in the context of Reformation.
They Took Us Seriously Then: Image of A Woman of the First Half of the 20th Century in Letters Between A. Afanasyeva and P. Varkhoeva
Authors: Савицкий И.В.
Published: October 2023

В статье анализируются письма ленинградской пенсионерки П.В. Вархоевой, сохранившиеся в личном фонде петрозаводского историка А.И. Афанасьевой. Специфика текста позволяет использовать гендерный подход и анализировать женский взгляд на региональную общественную жизнь 1920–1940-х гг. В задачу статьи входит изучение женского восприятия отношений внутри управленческих структур первых послереволюционных десятилетий. Высокая общественная активность Вархоевой давала ей возможность общения как с руководством Автономной Карельской ССР, так и с поселковой администрацией, постепенно соединяя воспоминания в единый нарратив. Меморизация впечатлений о карельской юности и пережитой Блокаде кристаллизировала в памяти оптимистичные сюжеты, богатые авторской рефлексией. Не менее интересны и коммуникативные аспекты эпистолярных отношений, в т. ч. способы влияния мемуариста на изучающего его материалы историка. Анализ писем Вархоевой позволяет рельефно выделить возрастные и гендерные различия в отношениях между людьми 1920-х гг., проследить ироничную рефлексию мемуариста в восприятии себя и окружающих, а также способы защиты от негативных воспоминаний начала 1940-х гг. Исследование также подтверждает ряд концепций о практике женской меморизации и влиянии на нее со стороны гендерной политики в СССР.

The article analyzes the letters of a Leningrad pensioner Praskovya Vasilyevna Varkhoeva from the private archive of a Petrozavodsk historian Alexandra Ivanovna Afanasyeva. The specificity of the text enables to use the gender approach for examining a woman’s view of the regional public life in the 1920–40s. The aim of the research was to study a woman’s perception of the internal relations in the administrative apparatus during the first post-Revolution decades. As a prominent public activist Praskovya Varkhoeva interacted with the authorities of the Karelian Autonomous Soviet Socialist Republic and the administration of her village, gradually combining her memories into a single narrative. The memorialization of her young years in Karelia and her survival during the Leningrad Siege eventually crystallized the optimistic life stories enriched with the author’s reflection. Of special interest are also the communicative aspects of the studied epistolary relationship, namely the means used by the memoirist to exert some influence on the researcher. Using Varkhoeva’s letters for analyzing the specific historical situation helps to reveal clear age and gender distinctions in the relations between people in the 1920s, to trace the elements of ironic reflection in the memoirist’s perception of herself and people around her, and to identify her ways of protection against the negative memories of the early 1940s. The conducted research also confirms a number of concepts concerning the women’s memoralization practices and how they were influenced by the USSR’s gender policy.
Soviet Journalism of the “Thaw” Period: Experience of Modal Biography
Authors: Орлов И.Б. , Цыганова Л.А.
Published: October 2023

В статье через призму биографии журналиста А.И. Распевина, работавшего в довоенные и послевоенные годы в разных региональных и центральных изданиях, раскрываются общие вехи истории советской журналистики. Основной фокус исследования направлен на реконструкцию профессиональной деятельности журналиста как типичной для целого поколения журналистов-шестидесятников, вписанной в широкий социокультурный контекст эпохи. Истоки трансформаций журналистики в предвоенные годы, периоды «оттепели» и «застоя» можно найти в журналистике периода нэпа и «большого скачка», во фронтовой очеркистике и репортажах и проследить по изменениям повестки дня, форматов подачи материала, а также жанров, которые становились актуальными и востребованными. Так как пик творческой деятельности журналиста пришелся на период хрущевского правления, в статье особое внимание обращается на феномен «оттепельной» журналистики.

This article is devoted to the history of Soviet journalism during the "Thaw" period through the prism of the biography of the journalist A.I. Raspevin, who worked in newspapers and magazines: "Crocodile", "Soviet Press", "Journalist" and "Soviets of Working People's Deputies", "Pravda", "Izvestia" and "Economic Newspapers". The focus of the study is aimed at the reconstruction of the professional activity of a journalist as typical for a whole generation of journalists of the sixties, inscribed in the socio-cultural context. And, on the transformation of journalism during the years of the “Thaw”, the origins of which can be found in military essays and reports, changing the agenda, formats for presenting material, genres that were relevant and in demand.
The Image of Russian Pan-Slavism in German Military-Political Leadership of 1870s and 1880s
Authors: Власов Н.А.
Published: October 2023

Последняя треть XIX в. стала временем значительного ухудшения российско-герман-ских отношений. Важной причиной были действия германского политического и военного руководства, основанные на определенных представлениях о Российской империи, в т. ч. о российском панславизме. Целью статьи является выяснение особенностей образа российского панславизма у германской военно-политической элиты (военных и государственных деятелей). В результате изучения широкого круга разнообразных источников можно сделать вывод о том, что понятие «панславизм» активно использовалось в указанной среде с конца 1870-х по конец 1880-х гг. в качестве собирательного термина для обозначения разных политических и общественных течений, направленных на изменение внутренней и внешней политики России. Панславизм воспринимался всеми представителями германской военно-политической элиты вне зависимости от их взглядов как крайне могущественная, иррациональная и потому опасная сила, стремившаяся к войне с Германией.

The last third of the 19th century was a time of significant deterioration in Russian-German relations. Among important reasons were the actions of the German political and military leadership, based on certain ideas about the Russian Empire, including pan-Slavism. The goal of this article is to determine the characteristic features of the image of Russian pan-Slavism among the German military-political elite. After studying a wide range of various sources, it can be concluded that the concept of "pan-Slavism" was actively used by German politicians and generals from the late 1870s to the late 1880s as a term for all trends aimed at changing the domestic and foreign policy of Russia. Pan-Slavism was perceived as an extremely powerful, irrational, and therefore dangerous force, striving for war with Germany.
“Between the Scylla of the Ticket Booth and the Charybdis of Ideology": On the Experience of Historical Interpretation of Soviet Rural Cinema
Authors: Сальникова А.А.
Published: October 2023

Статья представляет собой размышления по поводу монографии Л.Н. Мазур и О.В. Горбачева «Советские фильмы о деревне: опыт исторической интерпретации художественного образа» (2022), посвященной методологическим, теоретическим и конкретно-предметным вопросам изучения советских художественных фильмов как уникального источника по истории российской деревни ХХ века. Особое внимание уделено специфике транскрибирования, «прочтения» и интерпретации авторами монографии художественного кинематографического текста, выявлению ими его информационной отдачи в процессе реконструкции основных сюжетов советской сельской истории и сельской повседневности. Скрупулезный анализ советской «деревенской» фильмографии 1920-х – начала 1990-х гг. позволил авторам книги рассмотреть это кино как образец явного социального заказа, репрезентирующего трансформирующуюся позицию власти по отношению к советскому крестьянству, но в то же время получить эксклюзивные сведения о жизни советской деревни, отсутствующие в источниках иной типо-видовой принадлежности.

The article is a reflection on the monograph by Ludmila N. Mazur and Oleg V. Gorbachev "Soviet films about the village: the experience of historical interpretation of the artistic image" (2022). It is dedicated to the methodological, theoretical, and specific-object issues of studying the Soviet feature films as a unique source on the history of the Russian village of the 20th century. Particular attention is paid to the specifics of transcribing, "reading" and interpretation by the authors of the monograph of the cinematographic text, the identification of its informative impact in the reconstruction of the main plots of Soviet rural history and rural daily life. A scrupulous analysis of the Soviet "village" filmography of the 1920s ­− early 1990s allowed the authors of the book to consider this cinema as an example of a clear social order, which represents the transforming position of the authorities in relation to the Soviet peasantry. However, at the same time it allows to obtain exclusive information about the life of the Soviet village, missing in sources of other type and species.