bluuebunny/crossref_metadata_2025 huggingface dataset:
Sensing Method Using Multiple Quantities for Diagnostic of Insulators in Different Ambient Conditions
Authors: Dolník Bystrík , Šárpataky Ľuboš , Kolcunová Iraida , Havran Peter
Published: February 2022

Insulators are one of the many components responsible for the reliability of electricity supply as part of transmission and distribution lines. Failure of the insulator can cause considerable economic problems that are much greater than the insulator cost. When the failure occurs on the transmission line, a large area can be without electricity supply or other transmission lines will be overloaded. Because of the consequences of the insulator’s failure, diagnostics of the insulator plays a significant role in the reliability of the power supply. Basic diagnostic methods require experienced personnel, and inspection requires moving in the field. New diagnostic methods require online measurement if it is possible. Diagnostic by measuring the leakage current flowing on the surface of the insulator is well known. However, many other quantities can be used as a good tool for diagnostics of insulators. We present in this article results obtained on the investigated porcelain insulators that are one of the most used insulation materials for housing the insulator’s core. Leakage current, dielectric loss factor, capacity, and electric charge are used as diagnostic quantities to investigate porcelain insulators in different pollution conditions and different ambient relative humidity. Pollution and humidity are the main factors that decrease the insulator´s electric strength and reliability.
FL-PMI: Federated Learning-Based Person Movement Identification through Wearable Devices in Smart Healthcare Systems
Authors: Arikumar K. S. , Prathiba Sahaya Beni , Alazab Mamoun , Gadekallu Thippa Reddy , Pandya Sharnil , Khan Javed Masood , Moorthy Rajalakshmi Shenbaga
Published: February 2022

Recent technological developments, such as the Internet of Things (IoT), artificial intelligence, edge, and cloud computing, have paved the way in transforming traditional healthcare systems into smart healthcare (SHC) systems. SHC escalates healthcare management with increased efficiency, convenience, and personalization, via use of wearable devices and connectivity, to access information with rapid responses. Wearable devices are equipped with multiple sensors to identify a person’s movements. The unlabeled data acquired from these sensors are directly trained in the cloud servers, which require vast memory and high computational costs. To overcome this limitation in SHC, we propose a federated learning-based person movement identification (FL-PMI). The deep reinforcement learning (DRL) framework is leveraged in FL-PMI for auto-labeling the unlabeled data. The data are then trained using federated learning (FL), in which the edge servers allow the parameters alone to pass on the cloud, rather than passing vast amounts of sensor data. Finally, the bidirectional long short-term memory (BiLSTM) in FL-PMI classifies the data for various processes associated with the SHC. The simulation results proved the efficiency of FL-PMI, with 99.67% accuracy scores, minimized memory usage and computational costs, and reduced transmission data by 36.73%.
Decision Support System to Classify and Optimize the Energy Efficiency in Smart Buildings: A Data Analytics Approach
Authors: Peña Manuel , Biscarri Félix , Personal Enrique , León Carlos
Published: February 2022

In this paper, an intelligent data analysis method for modeling and optimizing energy efficiency in smart buildings through Data Analytics (DA) is proposed. The objective of this proposal is to provide a Decision Support System (DSS) able to support experts in quantifying and optimizing energy efficiency in smart buildings, as well as reveal insights that support the detection of anomalous behaviors in early stages. Firstly, historical data and Energy Efficiency Indicators (EEIs) of the building are analyzed to extract the knowledge from behavioral patterns of historical data of the building. Then, using this knowledge, a classification method to compare days with different features, seasons and other characteristics is proposed. The resulting clusters are further analyzed, inferring key features to predict and quantify energy efficiency on days with similar features but with potentially different behaviors. Finally, the results reveal some insights able to highlight inefficiencies and correlate anomalous behaviors with EE in the smart building. The approach proposed in this work was tested on the BlueNet building and also integrated with Eugene, a commercial EE tool for optimizing energy consumption in smart buildings.
Contextual Detection of Pedestrians and Vehicles in Orthophotography by Fusion of Deep Learning Algorithms
Authors: Ansarnia Masoomeh Shireen , Tisserand Etienne , Schweitzer Patrick , Zidane Mohamed Amine , Berviller Yves
Published: February 2022

In the context of smart cities, monitoring pedestrian and vehicle movements is essential to recognize abnormal events and prevent accidents. The proposed method in this work focuses on analyzing video streams captured from a vertically installed camera, and performing contextual road user detection. The final detection is based on the fusion of the outputs of three different convolutional neural networks. We are simultaneously interested in detecting road users, their motion, and their location respecting the static environment. We use YOLOv4 for object detection, FC-HarDNet for background semantic segmentation, and FlowNet 2.0 for motion detection. FC-HarDNet and YOLOv4 were retrained with our orthophotographs dataset. The last step involves a data fusion module. The presented results show that the method allows one to detect road users, identify the surfaces on which they move, quantify their apparent velocity, and estimate their actual velocity.
Eco-Friendly and Sensitive HPLC and TLC Methods Validated for the Determination of Betahistine in the Presence of Its Process-Related Impurity
Authors: Ibrahim Adel Ehab , El Deeb Sami , Abdellatef Hisham Ezzat , Hendawy Hassan A. M. , El-Abassy Omar M. , Ibrahim Hany
Published: February 2022

Reducing the amounts consumed of organic solvents while keeping good chromatographic performance has been a significant step towards the greening of analytical methodologies. When sodium dodecyl sulfate (SDS) and Brij-35 surfactants are combined in a mobile phase, they can be used as a green alternative to organic modifiers. Surfactants have numerous advantages, including low cost and toxicity, safe environmental disposal, and unique selectivity, in addition to high solubilization capabilities. In this research, two highly selective chromatographic methods were adopted for the determination of betahistine (BHS) in the presence of its pharmacopeial impurity 2-(2-hydroxyethyl)pyridine (HEP). A solvent-free HPLC method was validated, in which the mixture was separated using a C18 column (3.5 µm, 75.0 × 4.6 mm) and a mobile phase composed of 0.01 M Brij-35, 0.12 M SDS, and 0.02 M disodium hydrogen phosphate adjusted to a pH of 5.5 using phosphoric acid. The flow rate was 1.5 mL min−1 and the resolved peaks were detected at 260 nm. Another HPTLC-densitometric method was validated using HPTLC aluminum plates coated with silica gel 60 F254 as the stationary phase and a developing system consisting of methylene chloride/methanol/ethyl acetate/ammonia (at a ratio of 5:2:2:0.2 by volume); the separated bands were scanned at 260 nm.
Long-Term Outcomes of Kidney Transplant Recipients with Glomerulonephritides by Induction Type and Steroid Avoidance
Authors: Ravipati Prasanth , Jackson Scott , Tumer Gizem , Nachman Patrick , Riad Samy
Published: February 2022

Kidney transplant programs have different approaches to induction immunosuppression, and conflicting data exist on the role of steroid maintenance in recipients with glomerulonephritis (GN). GN patients are unique because of a higher risk for immune system exhaustion due to prior exposure to immunosuppressants to treat their GN; this raises questions regarding the optimal immunosuppression needed for transplant success and reduction of complications. We sought to assess the effect of induction type and steroid maintenance on the recipient and kidney graft survival in those with IgA nephropathy (IgAN), systemic lupus erythematosus related GN (SLE), small-vessel vasculitis (SVV), and anti-glomerular basement membrane disease (anti-GBM). We analyzed the Scientific Registry of Transplant Recipients (SRTR) database for adult, primary kidney recipients with the above glomerulonephritides through September 2019. Kaplan–Meier curves were generated to examine kidney graft and recipient survival. We used multivariable Cox proportional hazard models to investigate the impact of induction type and steroid maintenance in each group separately. Our study included 9176 IgAN, 5355 SLE, 1189 SVV, and 660 anti-GBM recipients. Neither induction type nor steroid maintenance therapy influenced recipient or death-censored graft survival in this cohort of recipients. Our findings provide an opportunity for recipients with a history of one of the studied glomerulonephritides to receive a more tailored immunosuppression regimen, considering their previous exposure to immunosuppressants.
The Effect of Age on the Grouping of Open Clusters: The Primordial Group Hypothesis
Authors: Casado Juan
Published: February 2022

The Primordial Group hypothesis states that only sufficiently young open clusters (OCs) can be multiple, and old OCs are essentially isolated. We tested this postulate through four different studies using a manual search of Gaia EDR3 and extensive literature. First, we revisited the work of de La Fuente Marcos and de La Fuente Marcos (2009), which states that only ca. 40% of OC pairs are of primordial origin. However, no plausible binary system among their proposed OC pairs having at least one member older than 0.1 Gyr was found. Second, we researched the OCs < 0.01 Gyr old in Tarricq et al. (2021) and found that ca. 71% of them remain in their primordial groups. Third, a similar study of the oldest OCs (age > 4 Gyr) showed that they are essentially alone. Forth, the well-known case of the double cluster in Perseus and some other binary systems described in the literature were also shown to accommodate the title hypothesis. A simplified bimodal model allows for retrieval of the overall fraction of related OCs (approximately 12–16%) from our results, assuming that young clusters remain associated at ~0.04 Gyr. The obtained results further support that OCs are born in groups (Casado 2021).
Geodesics for the Painlevé–Gullstrand Form of Lense–Thirring Spacetime
Authors: Baines Joshua , Berry Thomas , Simpson Alex , Visser Matt
Published: February 2022

Recently, the current authors have formulated and extensively explored a rather novel Painlevé–Gullstrand variant of the slow-rotation Lense–Thirring spacetime, a variant which has particularly elegant features—including unit lapse, intrinsically flat spatial 3-slices, and a separable Klein–Gordon equation (wave operator). This spacetime also possesses a non-trivial Killing tensor, implying separability of the Hamilton–Jacobi equation, the existence of a Carter constant, and complete formal integrability of the geodesic equations. Herein, we investigate the geodesics in some detail, in the general situation demonstrating the occurrence of “ultra-elliptic” integrals. Only in certain special cases can the complete geodesic integrability be explicitly cast in terms of elementary functions. The model is potentially of astrophysical interest both in the asymptotic large-distance limit and as an example of a “black hole mimic”, a controlled deformation of the Kerr spacetime that can be contrasted with ongoing astronomical observations.
Exploring the Role of Testosterone Replacement Therapy in Benign Prostatic Hyperplasia and Prostate Cancer: A Review of Safety
Authors: Rizzuti André , Stocker Gustavo , Santos Heitor O.
Published: February 2022

Increased risk of prostate diseases triggered by testosterone replacement therapy (TRT) remains a worldwide concern. That said, we reviewed the safety of TRT in the spheres of benign prostatic hyperplasia (BPH) and prostate cancer (PCa), exploring clinical findings in this regard. Compelling evidence based on meta-analyses of randomized and observational studies indicates safety for TRT in patients suffering from prostate disorders such as BPH and PCa, at the same time improving lower tract urinary symptoms. Thus, the harmful relationship geared toward androgens and BPH seems to be overestimated as TRT has sufficient safety and, if properly prescribed, may counteract several metabolic problems. Even after PCa treatment, the benefits of TRT could outweigh the risk of recurrence, but further long-term randomized clinical trials are needed to elucidate unresolved questions.
Impact of Local and Demographic Factors on Early COVID-19 Vaccine Hesitancy among Health Care Workers in New York City Public Hospitals
Authors: Afzal Afsheen , Shariff Masood A. , Perez-Gutierrez Victor , Khalid Amnah , Pili Christina , Pillai Anjana , Venugopal Usha , Kasubhai Moiz , Kanna Balavenkatesh , Poole Brian D. , Pickett Brett E. , Redd David S. , Menon Vidya
Published: February 2022

Despite the development of several effective vaccines, SARS-CoV-2 continues to spread, causing serious illness among the unvaccinated. Healthcare professionals are trusted sources of information about vaccination, and therefore understanding the attitudes and beliefs of healthcare professionals regarding the vaccines is of utmost importance. We conducted a survey-based study to understand the factors affecting COVID-19 vaccine attitudes among health care professionals in NYC Health and Hospitals, at a time when the vaccine was new, and received 3759 responses. Machine learning and chi-square analyses were applied to determine the factors most predictive of vaccine hesitancy. Demographic factors, education, role at the hospital, perceptions of the pandemic itself, and location of work and residence were all found to significantly contribute to vaccine attitudes. Location of residence was examined for both borough and neighborhood, and was found to have a significant impact on vaccine receptivity. Interestingly, this borough-level data did not correspond to the number or severity of cases in the respective boroughs, indicating that local social or other influences likely have a substantial impact. Local and demographic factors should be strongly considered when preparing pro-vaccine messages or campaigns.
Development of Next-Generation Vaccines
Authors: Imai Takashi
Published: February 2022

The battle between pathogens and hosts began on primitive Earth, and will probably continue forever [...]
Transfer of Statistical Customer Data into Relevant Parameters for the Design of Vehicle Drive Systems
Authors: Mieth Raphael , Gauterin Frank , Pauli Felix , Kraus Harald
Published: February 2022

Vehicle drive systems are often oversized for common customer operation in order to cover the high demands of rare driving events such as towing a trailer, high acceleration or steep inclines. This high torque and power requirement affects the efficiency map and the highest efficiency is around the area of increased torque and speed. However, in everyday use, drive systems are mostly driven by customers at low speed and load, and therefore are not operating in the most efficient area. Designing a drive system that only covers the area of highest customer operation can increase efficiency by moving the sweet spot of efficiency to the relevant area, and thus reduce energy consumption. Therefore, customer data need to be analyzed in order to identify customer requirements and to localize the area of greatest operation. The method presented in this paper analyzes customer data in order to identify design-relevant parameters for a customer-specific drive system design. The available customer data results from event-based counts and are submitted as a statistical frequency distribution. These statistics are compared with discrete time series recorded during test drives in order to derive representative time series that correspond to customer behavior. By applying the time frame-based load analysis to these relevant time series, the desired design-relevant parameters are pointed out.
Theater without Borders: To Raise the Question of Blurring the Line between Professional and Amateur Creativity
Authors:   Krasnodar state institute of culture, Tsishkovskaya M.S.
Published: February 2022

Recently, the amateur theater movement, which seemed to have lost its significance three decades ago, is reviving and, moreover, transforming, now qualitatively different from the socio-cultural phenomenon that it was in the past. This paper examines the development of amateur creativity at the present stage. We will talk about private commercial theaters, amateur studios and laboratories, which over the past decade have not only gained wide popularity, but also, in the context of postmodern transformations, have become direct competitors to professional art, thereby blurring the boundaries between professional and amateur creativity. The functions of professional theaters, the tasks and problems that arise before them, have also affected the amateur art to the same extent. The author comes to the conclusion that the boundaries between professional and amateur theater are gradually blurring, which, in the near future, may lead to new global transformations in the field of theater culture.
Historiographic analysis of Leslie White's critique of the concept of culture in Russian literature
Authors:   Samara National Research University named after academician S.P. Korolev, Zhigalov A.V. Zhigalov A.V.
Published: February 2022

The article analyzes the criticism of the conceptual developments of Leslie white's theory of culture in Russian literature. The author, being an investigator of the theory of the evolutionary development of cultural processes, enters into a correspondence polemic with famous figures of the Humanities, appealing to the words of white, as well as on the basis of his own observations and conclusions.
Verbalization of "primary tectonal projections" of Cninese culture in the corpus of national patriotic song texts of the Chinese Republic (Taiwan) and the PRC
Authors:   Oriental Institute — School of Regional and International Studies of the Far Eastern Federal University, Ishutina Y.A.
Published: February 2022

"Primary tectonic projections" of culture are realized in the discourse of nationalism of the PRC and the Chinese Republic (Taiwan), receiving verbalization in the texts of the national patriotic songs of these states. Being laconic and capacious symbolically, the lyrics of hymns and patriotic songs carry out the main task, which is to consolidate these symbols in everyday life and initiate the process of participation of the citizen with the national state. The relevance of the research topic is due to the intensification of the processes of national identity of the Chinese continental and island communities, which have been pursuing alternative development paths for more than 70 years. The novelty lies in the identification of significant projections of the primary tectons of Chinese culture, representing a number of mythologemes, numbers, visual and role images in the national text of the PRC and the Chinese Republic (Taiwan). English version of the article is available at URL: https://panor.ru/articles/verbalization-of-primary-tectonic-projections-of-chinese-culture-in-the-corpus-of-national-patriotic-song-lyrics-of-rc-taiwan-and-the-prc/78345.html
The procedure for remuneration of creative workers: Russian practice
Authors:   Udmurt State University, Russkikh T.V.
Published: February 2022

The salary received by an employee under an employment contract is, as a rule, his only source of livelihood. Within the framework of this article, some problems of remuneration of creative workers are considered during the period when they do not participate in the creation and (or) performance (exhibit) of works or do not act. The article concludes that abuse by employers of the freedom granted to them by Part 5 of Article 157 of the Labor Code of the Russian Federation leads to a significant deterioration in the position of creative workers in comparison with workers in other professions. At the same time, the norms of differentiation should not be interpreted arbitrarily in violation of the Constitution of the Russian Federation and the fundamental norms of labor law, be discriminatory. It is concluded that the freedom of the employer as a party to the employment contract, even within the framework of the institution of remuneration, should be limited within certain limits. The ways of improving the current labor legislation are proposed.
ANALYSIS OF STUDENTS’ ABILITY IN APPLYING SIMPLE PAST TENSE IN RECOUNT TEXT AT SMP N 1 PANGARIBUAN
Authors: Pakpahan Herawati
Published: February 2022

Abstract

 

Recount text is a kind of text in english that tell about a story, actions or event which use simple past tense. Meanwhile, simple past tense is an event that happen in past, the characteristic of simple past tense is using verb 2. Students’ability are a condition to determine students skill in applying simple past tense in recount tense. The aim of this research were to analyzed the students’ ability in applying simple past tense in recount text. This research performed at eight grade in Smp N 1 Pangaribuan. Researcher used qualitative research designs. The data was collected by test, and questionnaire. Based on students test result, the average score of 20 students at eight grade in Smp N 1 Pangaribuan was 55,4. The data from questionnaire showed that 11 from 20 students couldn’t remember the pattern of simple past tense. 12 from 20 students didn’t know about simple past tense or couldn’t make sentence in simple past form. 15 from 20 students couldn’t remember verb in simple past, 12 from 20 students thought that recount text was difficult. And 17 from 20 students couldn’t write recount text correctly.

Keywords : Students’ Ability, Simple Past Tense, Recount Text
MORAL VALUE AND CHARACTER BUILDING EDUCATION IN BATAK TOBA’S BATU GANTUNG
Authors: Tampubolon Mentary indrayana , Simbolon Rointan friska , Br Sitepu Dessy natalia , purba Febrianti atalia
Published: February 2022

Abstract

 

This research was Conducted by using Library Research Method. Based on the problem of the study above, the objective of the study are to find out the moral values found in the Batak Toba’s Batu gantung folklore and to find out the moral values found in Batak Toba’s Batu Gantung applied in Students’ character building. In this research, the writer used qualitative method because this study focuses on the evaluation or interpretation of the written fabric in context.

Materials can encompass textbooks, newspapers, magazines, papers, films, manuscripts, articles, and many others. To achieve easiness of this study and to reply the research problem, after the data have been collected, then the creator analyzed them systematically. After analyzing the folklore, the researcher  found  some  moral lessons  and  character  building  education  such as; kindness,compassion, courage, enthusiasm, justice, responsibility, and caring.

Keywords: moral value, batu gantung folklore, character building
Figurative languages in novel: A comparative study between Layla Majnun and Romeo and Juliet Novels
Authors: Samosir Rebekka Basa Natalia , Simanjuntak Theresia Marini , Lumban Batu Katri Helen , Zai Kristiani Dewi , S.S., M.Hum., Fachri Yunanda,
Published: February 2022

Abstract :

Layla Majnun is one of the works of Nizami and Romeo and Juliet is one of the works of William Shakespeare. both novels are romance tradegy novels. Romance tragedy novels usually use a lot of figurative language to beautify the language. This study aims to describe some of the types of figurative language in the novel Layla Majnun, to describe some of the types of figurative language in the novel Romeo and Juliet, to describe the comparison of the types of figurative languages found in novel Layla Majnun and novel Romeo and Juliet. The data obtained for this study are qualitative data. This means, the data are not in the forms of numeric. The data were discourse, such as dialogues, descriptions, ideas or perspectives. The main data of the study are taken from the tragedy novels. The collected data are mostly in the forms of discourse and dialogues taken from the novels as the writers of the novels often apply figurative languages to express their ideas. There are several figurative languages in the discourse and dialogues obtained from the novels which could be interpreted by using Pragmatics theory to identify the meaning behind them. The results of this study indicate that there are similarities and differences in figurative languages in the two novels. The similarities between the two novels are Personification, Metaphore, Hyperbole, and Simile. The differences between the two novels are: Parable, Embodiment, Cynicism, Repetitive, and Irony.

Keywords : Figurative Language, Comparative Study, Layla Majnun Novel, Romeo and Juliet Novel.
Огляд математичних моделей оцінки параметрів ударної хвилі вибуху зарядів вибухової речовини
Authors: Бісик Сергій Петрович , Давидовський Леонід Сергійович , Телепа Максим Вікторович , Нагорський Олександр Геннадійович , Бісик Світлана Володимирівна , Новосад Андрій Анатолійович
Published: February 2022

У статті проведений огляд математичних моделей різних авторів для оцінки параметрів ударної хвилі вибуху зарядів вибухової речовини. З їх використанням побудовані залежності між масштабним коефіцієнтом та основними параметрами ударної хвилі, такими як: швидкість фронту, час прибуття до об’єкту, значення максимального тиску на фронті, значення тиску негативної фази, час дії позитивної та негативної фаз, імпульс позитивної та негативної фаз. Розрахунок цих параметрів передбачає врахування маси вибухової речовини, відстані від центру заряду до точки в просторі, швидкості розповсюдження звуку у повітрі та атмосферного тиску.Порівняння отриманих залежностей з експериментальними даними вимірювання параметрів підриву зарядів вибухової речовини масою до 100 г показує, що для певних математичних моделей розраховані значення тиску та часу дії позитивної фази вибуху можуть значно відрізнятись від отриманих експериментальних даних.
The Effect of Environmental Accounting on the Increase in Firm Value
Authors: Effendi Bahtiar
Published: February 2022

This study aims to analyze the factors of environmental accounting which consist of material inputs, non-product output, compliance aspects, transportation aspects, other aspects, supplier assessment, and environmental complaints mechanisms to increase firm value. The sample in this study was 71 respondents from companies in Banten which were determined based on the purposive sampling method. Then the data were analyzed using multiple linear regression methods. The results showed that environmental accounting which is proxied by non-product output, other aspects, and environmental complaints mechanisms have a significant positive effect on increasing firm value. Furthermore, it was found that there was a significant negative effect between material input and supplier assessment on the increase in firm value. Also, it was found that the compliance aspect had a positive and insignificant effect on the increase in firm value and the transportation aspect had a negative and insignificant effect on the increase in firm value. Finally, the results of this study found that environmental accounting simultaneously has a significant effect on firm value.
Analysis of Open-Source Solution for Point of Sales Inventory Management System
Authors: Marico Joxel , Purnama James , Galinium Maulahikmah
Published: February 2022

Package other popular food distributor businesses. To gain advantage, they used newest Point of Sales (POS) for their business. POS allows user mood to do transaction between buyer and cashier, manage stock, etc. Unfortunately after several months, their business closed down, because the newest POS is not designed for their food distributor. ,The purpose of this research is to understand how POS would affect the business and why POS is valuable and important for business. The goal of this research is to find out which POS is suitable for both small and large business. There are four open-source POS to be analyzed, which are Odoo, E-hopper, Loyverse and Aronium. fOr Comparing Open Source software Evaluation Methods (FOCOSEM) is used to compare their features. In conclusion, only one shop. If the business owner wants to open another shop at different location but he/ she wants to keep track another shop, E-hopper or Loyverse is recommended. If the business owner wants to use mobile devices for easy setup, Loyverse is recommended. If the business owner prefers using PC, then E-hopper is recommended. For business owner who is conducting export and import then Odoo is recommended.
Do ESG Strategies Foster or Impede Corporate Innovation: Evidence from Asia-Pacific
Authors: Al-Jaifi Hamdan Amer Ali
Published: February 2022

This study examines the joint and separate effects of Environmental (E), Social (S), and Governance (G) scores on corporate innovation. Using a 5,566 yearly-firms observation from listed firms operating in the Asia Pacific region over 2011–2020, the study finds that the aggregate ESG score and its two sub-pillars (social and governance) have insignificant impacts on corporate innovations. However, environmental activities have a significant and negative impact on corporate innovation. This finding implies that environmental activities stipulate corporate innovation as it deviates firms’ resources from the value-added activities that enhance innovation. Hence, firms need to consider the trade-off between engaging highly in environmental activities and impeding corporate innovation. These findings enrich the literature of ESG and innovation and provide valuable information for firms and their stakeholders, including regulators.
Features of the Axiological Approach when Providing Psychological Assistance to Combatants with Post-Traumatic Stress Disorder
Authors: Попелюшко Р.П.
Published: February 2022

Целью данной работы является анализ особенностей применения аксиологического подхода при оказании психологической помощи комбатантам с посттравматическим стрессовым расстройством. Обобщены взгляды зарубежных и отечественных ученых и практиков относительно понятия «ценности», его видов, форм и характеристик. Также было рассмотрено современное понимание критериев и категорий ценностей. Были проанализированы особенности понимания понятия «ценности» на философском, психологическом и социологическом уровнях. Одним из показателей эффективности медико-социально-психологической реабилитации комбатантов с посттравматическим стрессовым расстройством является изучение аксиогенеза и трансформации (а в некоторых случаях и формирования) ценностных ориентаций у комбатантов. Проблема комплексного и поэтапного формирования системы ценностных ориентаций комбатанта для качественного выполнения им своих служебных обязанностей является основоположной в ходе приобретения им соответствующих компетенций гражданского, философского и украиноведческого формата. Результаты проведенного исследования могут быть использованы при разработке мероприятий по оказанию психологической помощи комбатантам с посттравматическим стрессовым расстройством.

The aim of this work is to analyze the features of the application of the axiological approach in theprovision of psychological assistance to combatants with post-traumatic stress disorder. The viewsof foreign and domestic scientists and practitioners on the concept of “value”, their types, formsand characteristics are generalized. The modern understanding of the criteria and categories ofvalues is also reviewed. The features of understanding the concept of “values” at the philosophical,psychological and sociological levels were analyzed.One of the indicators of the effectiveness of medical and socio-psychological rehabilitation ofcombatants with post-traumatic stress disorder is the study of axiogenesis and transformation(and in some cases, the formation) of value orientations in combatants. The problem of a complexand gradual formation of the system of value orientations of a combatant, for the qualitativeperformance of their official duties, is fundamental in the course of acquiring the correspondingcompetencies of a civil, philosophical and Ukrainian studies format.The results of this study can be used to develop the measures to provide psychological assistance tocombatants with post-traumatic stress disorder.
Clinical and Psychological Aspects of Chronic Urological Pelvic Pain Syndrome
Authors: Мелёхин А.И.
Published: February 2022

В статье на примере современных биопсихосоциальных урологических моделей показано, что синдром хронической урологической тазовой боли (СХТБ) имеет мультифакторный генез и требует интегративного, мультидисциплинарного подхода (врач-уролог, врач-невролог иклинический психолог). В связи с этим выявление индивидуальных урологических клинических фенотипов пациентов позволяет выявить предрасполагающие, провоцирующие и поддерживающие факторы, определяющие течение заболевания и ответ на терапию. Описаны фенотипические урологические системы MAPP, UPOINT и DABBEC. Детализирована специфика психической коморбидности (депрессия, паническое расстройство, пограничное личностное расстройство и др.) у данной группы урологических пациентов. Показана связь симптомов депрессии и изменений в сексуальном функционировании с СХТБ. Впервые в России описаны модели «мочевой пузырь - кишечник - мозг» Л. Карстен; накопленного стресса и фальсификации тревоги, потери контроля у пациентов с СХТБ Д. Дасалакиса и модели влияния психического состояния пациента на мышечно-тонические проявления в урологической клинике Яонга Ки Кву. Систематизированы и описаны личностные особенности пациентов с СХТБ (нейротизм, уступчивость, открытость, добросовестность, сознательность, изменения в маскулинной идентичности, алекситимия, катастрофизация). Представлена тактика проведения экспресс-оценки и полной комплексной психологической оценки урологического пациента для построения эффективного лечения.

Using the example of modern biopsychosocial urological models, the article shows that thesyndrome of chronic urological pelvic pain has a multi-factorial genesis and requires an integrative,multidisciplinary approach (urologist, neurologist, and clinical psychologist). In this regard,the identification of individual urological clinical phenotypes of patients allows us to identifypredisposing, provoking and supporting factors that determine the course of the disease and theresponse to therapy. The following phenotypic urological systems are described: Marr, UPOINT, andDABBEC. The specifics of mental comorbidity (depression, panic disorder, borderline personalitydisorder, etc.) in this group of urological patients are detailed. The association of symptoms ofdepression and changes in sexual functioning with SHTB is shown. For the first time, the modelsof urinary-bladder-bowel-brain by L. Karsten are described; accumulated stress and falsification ofanxiety, loss of control in patients with urological pelvic pain by D. Dasalakis and models of theinfluence of the patient’s mental state on muscle-tonic manifestations in the urological clinic ofYaong Ki. Personal characteristics of patients with urological pelvic pain – neuroticism, compliance,openness, conscientiousness, changes in masculine identity, alexithymia, catastrophization – aresystematized and described. The tactics of conducting a full and rapid comprehensive psychologicalassessment of a urological patient is presented.
Chlortalidone in Modern Recommendations for Treatment of Arterial Hypertension
Authors: Нечесова Т.А.
Published: February 2022

Встатье приведен обзор эффективности и безопасности применения хлорталидона для лечения пациентов с артериальной гипертензией. Анализируются данные современных метаанализов метаболических эффектов диуретиков. Показано, что помимо гипотензивного действия у хлорталидона есть плейотропные эффекты, которые отличают его от других представителей класса диуретиков. Помимо реабсорбции натрия хлорталидон обладает способностью снижать сосудистое сопротивление, влияя на эндотелий и гладкие мышцы сосудов. Этот механизм действия препарата связан с его способностью ингибировать изоформы карбоангидразы за пределами почек. Препарат обладает вазодилатирующим эффектом, усиливает образование оксида азота, а также снижает агрегацию тромбоцитов и проницаемость сосудистой стенки. В клинических исследованиях доказано, что хлорталидон хорошо контролирует артериальное давление в ночные часы, снижает скорость распространения пульсовой волны и гипертрофию левого желудочка. Висследованиях SHEP, ALLHAT, MRFIT было доказано, что хлорталидон оказывает положительное влияние на жесткие конечные точки. В исследовании SHEP общая смертность в группе лечения хлорталидоном снизилась на 13%, количество инсультов на 36%. В рандомизированном исследовании MRFIT было показано, что хлорталидон в сравнении с гидрохлортиазидом обеспечивает снижение относительного риска сердечно-сосудистых осложнений на 21%.

The article provides the overview of the efficacy and safety of using chlorthalidone for treatment of patients with arterial hypertension. The data of modern meta-analyses of metabolic effects of diuretics are analyzed. It was showed that, in addition to the hypotensive effect, chlorthalidone has the pleiotropic effects that distinguish it from other representatives of the class of diuretics. In addition to sodium reabsorption, chlorthalidone has the ability to reduce vascular resistance, affecting the endothelium and smooth muscles of the vessels. This mechanism of action of the drug is associated with its ability to inhibit carbonic anhydrase isoforms outside kidneys. The drug has a vasodilating effect, enhances the formation of nitric oxide, and also reduces platelet aggregation and vascular wall permeability. In clinical studies, it was proved that chlorthalidone controls blood pressure at night, reduces the speed of the spread of the pulse wave and left ventricular hypertrophy. In SHEP, ALLHAT, MRFIT studies, chlorthalidone showed a positive effect on hard endpoints. In the SHEP study, overall mortality in the chlorthalidone treatment group decreased by 13%, and the number of strokes - by 36%. A randomized MRFIT trial showed that chlorthalidone compared with hydrochlorothiazide reduced the relative risk of cardiovascular complications by 21%.
Molecular Genetic Aspects of Drug-Induced Long QT Syndrome
Authors: Колоцей Л.В. , Снежицкий В.А.
Published: February 2022

Синдром удлиненного интервала QT (СУИ QT) может быть как врожденным, так и приобретенным, причем последний наиболее часто вызывается воздействием лекарственных препаратов. Клинические наблюдения показывают, что прием одних и тех же доз препаратов по-разному отражается на продолжительности интервала QT и риске возникновения желудочковой тахикардии типа «пируэт» у разных пациентов. Согласно концепции «резерва реполяризации» у пациентов с лекарственно-индуцированным СУИ QT существует генетически запрограммированный низкий резерв реполяризации, т. е. набор мутаций в генах ионных транспортеров, который не проявляется клинически до контакта с триггерным лекарственным препаратом. В течение последнего десятилетия идентифицирован ряд подобных «латентных» мутаций в генах врожденного СУИ QT и обнаружены функциональные полиморфизмы в тех же или иных генах, связанные с повышенной восприимчивостью к заболеванию. Методики полноэкзомного секвенирования и полногеномного поиска ассоциаций позволили оценить широкий спектр однонуклеотидных полиморфизмов в пределах всего экзома, а также определить взаимосвязь между геномными вариантами и клиническими фенотипами. В настоящем обзоре отражены основные достижения в области молекулярно-генетического направления диагностики лекарственно-индуцированного СУИ QT и дальнейшие перспективы исследований в данной области.

Long QT syndrome (LQTS) can be both congenital and acquired. The latter one is most often caused by the effects of drugs. Clinical observations show that taking the same doses of drugs has different effects on the duration of the QT interval and the risk of torsades de pointes in different patients. According to the “repolarization reserve” concept, patients with drug-induced LQTS have a genetically programmed low repolarization reserve, i.e. a set of mutations in the genes of ionic transporters that do not manifest clinically prior to the contact with the trigger drug. During the last decade, a number of “latent” mutations in the genes of the congenital LQTS have been identified and functional polymorphisms in the same genes associated with increased susceptibility to the disease have been found. The methods of the whole exome sequencing and genome-wide association studies let to evaluate a wide range of single nucleotide polymorphisms within the entire exome and to investigate the relationship between genomic variants and certain phenotypes. The present review reflects the main advances in the molecular genetic direction of diagnostics of drug-induced LQTS and further prospects for research in this area.
Prevalence and Pathogenesis of Anemia in Patients with Chronic Heart Failure
Authors: Ханюков А.А. , Песоцкая Л.А. , Сапожниченко Л.В. , Пампуха А.А.
Published: February 2022

Введение. Анемия часто является сопутствующим заболеванием при хронический сердечной недостаточности (ХСН), которое снижает толерантность к физической нагрузке, качество жизни и ухудшает прогноз у пациентов. Такое влияние обуславливает актуальность изучения распространенности и патогенеза анемии и железодефицитных состояний при ХСН. Цель. Провести обзор литературы, иллюстрирующей современные данные о распространенности и патогенезе анемии и дефицита железа у пациентов с хронической сердечной недостаточностью. Материалы и методы. В данной работе представлен обзор литературы, посвященной распространенности и патогенезу анемии и дефицита железа у пациентов с хронической сердечной недостаточностью, исходя из проведенного поиска англоязычных статей в базе PubMed за последние 20 лет по ключевым словам: анемия, дефицит железа, хроническая сердечная недостаточность, патогенез, распространенность. Результаты. Частота анемии и дефицита железа у пациентов с ХСН в среднем составляет 30-70% и 30-50% соответственно. Были выделены 6 факторов, которые могут стать причиной анемии у пациентов с ХСН: дефицит железа, воспаление, уровень эритропоэтина, лекарственные препараты, гемодилюция, медуллярная дисфункция. Причины абсолютного дефицита железа анорексия, кахексия, нарушение абсорбции железа, функционального хроническое воспаление. Выводы. Лучшее понимание патогенеза этих состояний у пациентов с ХСН позволит разработать новые методы лечения.

Intriduction. Anemia is often an associated disease in patients with chronic heart failure (CHF), which reduces exercise tolerance, quality of life, and worsens the prognosis in patients. This influence determines the relevance of knowledge of the prevalence and pathogenesis of these conditions in CHF. Purpose. Review of literature illustrating the current data about the prevalence and pathogenesis of anemia and iron deficiency in patients with chronic heart failure. Materials and methods. This work presents the review of literature about the prevalence and pathogenesis of anemia and iron deficiency in patients with chronic heart failure based on the search of English-language articles in the PubMed database for the last 20 years, by keywords - anemia, iron deficiency, chronic heart failure, pathogenesis, prevalence. Results. The frequency of anemia and iron deficiency in patients with CHF is about 30-70% and 30- 50%, respectively. Six factors can cause anemia in patients with CHF: iron deficiency, inflammation, erythropoietin levels, drugs, hemodilution, medullar dysfunction. The reasons for absolute iron deficiency are anorexia, cachexia, impaired absorption of iron, functional deficiency - chronic inflammation. Conclusion. Better understanding of the pathogenesis of these conditions in patients with CHF will let to develop the new methods of treatment.
Prospek Komoditi Jahe di Sumatera Barat
Authors: Wahyuni Esa Diya
Published: February 2022

Ginger plants have recently been in the spotlight of businesspeople in Indonesia. Ginger has a myriad of benefits. Besides being used for cooking spices, ginger can also boost the body’s immune system. Along with the inventions of the benefits of ginger plants, many people are interested in getting into the Ginger plants, many people are interested in getting into the ginger commodity business. This study aims to determine the prospect of a ginger commodity in West Sumatra in terms of two aspects, opportunity and threats. This research is conducted by a qualitative descriptive method using a literature study. The opportunity aspect shows five results. There is support from the West Sumatra government for ginger consumption, the increase of ginger price in Dharmasraya Regency, especially on red ginger. Ginger is one of the leading commodities in the Pesisir Selatan Regency. Helping to increase people’s income in the City/Regency in west Sumatra Province, and areas with a surplus of ginger production can be suppliers of ginger to other areas in West Sumatra Province. And from the threat aspect, the presence of domestically imported ginger affects the price of ginger in traditional markets, which tend to decline. The prospector business continuity of the ginger plant commodity in West Sumatra will last for a relatively long time because of the need for ginger commodity business is closely related to the price, production, and demand for both household and non-household consumption ginger needs in West Sumatra.
La ley de Salud Mental y Adicciones. Posibilidades de su implementación en un hospital de mediana complejidad de la Provincia de Santa Fe
Authors: Bonino María Noelia
Published: February 2022

El presente artículo se propone visibilizar el entrecruzamiento de las propuestas enunciadas en la Ley Nacional de Salud Mental y Adicciones (2010) con situaciones singulares de las prácticas clínicas, indagando las posibilidades y dificultades para implementar los lineamientos establecidos en las normativas nacional y provincial en un hospital de mediana complejidad de la provincia de Santa Fe, en el periodo comprendido entre 2015–2016. El estudio pretendió describir y comprender el modo de trabajo de los profesionales de salud mental, las intervenciones y las prácticas realizadas en la institución escogida. Comprendió a un conjunto de actores, que permitieron dar visibilidad a la heterogeneidad de perspectivas sobre la implementación de las normativas vigentes en los procesos de cuidado de las problemáticas de salud mental. Se implementaron distintas modalidades de elaboración y análisis de los datos. En el análisis de los datos se registró un proceso de avances y de cambios respecto a la inclusión y alojamientos en las internaciones de pacientes afectados por padecimientos de salud mental en el hospital general, pero también la emergencia de tensiones resultado de la persistencia de ciertas lógicas excluyentes y manicomiales.
Un equipo en juego, con toda la mar detrás. Procesos de trabajo y producción de Salud Mental
Authors: Bellezze Elisa
Published: February 2022

equipo interdisciplinario e interinstitucional de Puente de Tierra, una experiencia territorial de juego con niños, niñas y jóvenes en contextos de pobreza de la ciudad de Rosario. Se describe el dispositivo lúdico y su inscripción/ tensión respecto a la política pública. Luego, se reconstruye el proceso de trabajo durante el período estudiado, ordenando la información en torno a cuatro aspectos relevantes. Además, se articulan conceptualizaciones que dimensionan, por un lado, las dificultades de la práctica, y por otro, los recursos y herramientas clínicas con las que se cuenta para afrontarlas. El equipo en juego implica un entramado colectivo vinculado con la producción de salud mental, donde es central la dimensión per–elaborativa, creativa y de pensamiento crítico. Finalmente se esbozan reflexiones y nuevos interrogantes.