bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of microbial agents in tissue specimens of ocular and periocular sarcoidosis using a metagenomics approach
Authors: Shifera Amde Selassie , Pockrandt Christopher , Rincon Natalia , Ge Yuchen , Lu Jennifer , Varabyou Ales , Jedlicka Anne E. , Sun Karen , Scott Alan L. , Eberhart Charles , Thorne Jennifer E. , Salzberg Steven L.
Published: August 2021

Background: Metagenomic sequencing has the potential to identify a wide range of pathogens in human tissue samples. Sarcoidosis is a complex disorder whose etiology remains unknown and for which a variety of infectious causes have been hypothesized. We sought to conduct metagenomic sequencing on cases of ocular and periocular sarcoidosis, none of them with previously identified infectious causes.

Methods: Archival tissue specimens of 16 subjects with biopsies of ocular and periocular tissues that were positive for non-caseating granulomas were used as cases. Four archival tissue specimens that did not demonstrate non-caseating granulomas were also included as controls. Genomic DNA was extracted from tissue sections. DNA libraries were generated from the extracted genomic DNA and the libraries underwent next-generation sequencing.

Results: We generated between 4.8 and 20.7 million reads for each of the 16 cases plus four control samples. For eight of the cases, we identified microbial pathogens that were present well above the background, with one potential pathogen identified for seven of the cases and two possible pathogens for one of the cases. Five of the eight cases were associated with bacteria (Campylobacter concisus, Neisseria elongata, Streptococcus salivarius, Pseudopropionibacterium propionicum, and Paracoccus yeei), two cases with fungi (Exophiala oligosperma, Lomentospora prolificans and Aspergillus versicolor) and one case with a virus (Mupapillomavirus 1). Interestingly, four of the five bacterial species are also part of the human oral microbiome.

Conclusions: Using a metagenomic sequencing we identified possible infectious causes in half of the ocular and periocular sarcoidosis cases analyzed. Our findings support the proposition that sarcoidosis could be an etiologically heterogenous disease. Because these are previously banked samples, direct follow-up in the respective patients is impossible, but these results suggest that sequencing may be a valuable tool in better understanding the etiopathogenesis of sarcoidosis and in diagnosing and treating this disease.
Cost-effectiveness of hydroxychloroquine versus placebo for hand osteoarthritis: economic evaluation of the HERO trial
Authors: Ronaldson Sarah J , Keding Ada , Tharmanathan Puvan , Arundel Catherine , Kingsbury Sarah R , Conaghan Philip G , Torgerson David J
Published: August 2021

Background: An economic evaluation alongside the Hydroxychloroquine Effectiveness in Reducing symptoms of hand Osteoarthritis (HERO) trial was undertaken to assess the cost-effectiveness of hydroxychloroquine compared with placebo for symptomatic treatment of hand osteoarthritis for patients with at least moderate hand pain and inadequate response to current therapies.

Methods: A trial-based cost–utility analysis was undertaken from the perspective of the UK National Health Service and Personal Social Services over a 12-month time horizon, using evidence from 248 participants included in the HERO trial, conducted in England. Patient-level data were collected prospectively over a 12-month period, using participant-completed questionnaires and investigator forms, to collect healthcare utilisation, costs and quality-adjusted life years (QALYs) using the EQ-5D-5L. The base-case analysis was conducted on an intention-to-treat basis and used multiple imputation methods to deal with missing data. Results were presented in terms of incremental cost-effectiveness ratios (incremental cost per QALY) and net health benefit, with uncertainty surrounding the findings explored using cost-effectiveness acceptability curves.

Results: The base-case analysis estimated slightly lower costs on average (−£11.80; 95% confidence interval (CI) −£15.60 to −£8.00) and marginally fewer QALYs (−0.0052; 95% CI −0.0057 to −0.0047) for participants in the hydroxychloroquine group versus placebo group at 12 months. The resulting incremental cost-effectiveness ratio of £2,267 per QALY lost indicated that although costs were saved, health-related quality of life was lost. Even assuming symmetrical preferences regarding losses and gains for health benefits, the findings do not fall within the cost-effective region. Similar findings arose for analyses conducted from the societal perspective and using complete cases only.

Conclusions: This economic evaluation indicates that hydroxychloroquine is unlikely to provide a cost-effective pain relief option for improving health-related quality of life in adult patients with moderate-to-severe hand osteoarthritis.
Antithesis versus Inspiration: Chinese Clothing in the Eyes of Western Theorists and Fashion Designers
Authors: Grela-Chen Magdalena
Published: August 2021

Dress is a part of Chinese cultural heritage that has fascinated Western audiences for centuries. On the National List of Intangible Cultural Heritage of China, there are items related to textiles, embroideries and certain examples of Chinese clothing. This article analyses issues connected with the different uses of Chinese dress in the West. To fashion theorists such as Bell, Wilson, Sapir and Veblen, Chinese dress was the opposite of modern Western clothing and did not deserve to be called fashion. However, researchers such as Welters, Lillethun and Craik have opposed viewing fashion theory through a Eurocentric prism in their desire to rewrite fashion history. Fashion designers drew ideas from China, treating it as a source of inspiration to create their own original designs. For some of them, such as Yves Saint Laurent, it was a China of their imagination. In certain cases, they made use of porcelain designs or dragon motifs in their own collections, for instance, in designs by Cavalli and Ford. The incorporation of Chinese garments into Western collections has also become visible.
Use of pedometers in the workplace as a strategy to increase physical activity
Authors: Harrison Joanna , O'Donoghue Annette , Hill James
Published: August 2021

Lack of physical activity can have a negative impact on health outcomes. This is particularly relevant for desk-based workplaces where sitting for long periods is required. This commentary critically appraises and evaluates a Cochrane systematic review of workplace pedometer programmes for increasing physical activity.
QNI conference: Building back fairer
Authors: Oldman Crystal
Published: August 2021

After a challenging time for NHS professionals on the frontline of the Covid-19 pandemic, Crystal Oldman discusses the theme of the QNI annual conference, focusing this year on health inequalities
Multimodal multiphoton microscopy for protein crystal detection based on two-color ultrafast fiber laser source
Authors: Chung Hsiang-Yu , Cheng Qing-di , Schubert Robin , Chia Shih-Hsuan , Kärtner Franz X. , Chang Guoqing , Betzel Christian
Published: August 2021

We demonstrate label-free multiphoton microscopy including harmonic
generation and three-photon excitation fluorescence to score protein
crystals based on a novel fiber laser source that emits femtosecond
pulses at 775 nm and 1300 nm.
Spectral Linewidth Narrowing of two Broad Area Blue Laser Diode (445nm) with a Common External Cavity
Authors: Nyaupane Parashu , Likamwa Patrick L , Braiman Yehuda
Published: August 2021

Two high-power, watt-level broad area laser diodes (BALD) were simultaneously locked into a common external cavity made using a surface grating in Littrow configuration and the spectral linewidth of the combined laser beam was narrowed down from over a nm to 15 pm (FWHM).
Nonlinear Characterization of Laser Processed Polysilicon Waveguides for Integrated Photonics
Authors: MacFarquhar S. J. , Aktas O. , Oo S. Z. , Tarazona A. , Chong H. M. H. , Peacock A. C.
Published: August 2021

Polycrystalline silicon offers the full complement of functionality required for integrated optoelectronic systems, including nonlinear optical processing. Here we report low loss laser-crystallized polycrystalline silicon waveguides with nonlinear coefficients equivalent to those of crystalline silicon.
Hyperspectral Imaging Reflectometry for 3D Semiconductor Metrology
Authors: Kim Jinseob , Park Gwangsik , Han Daehoon , Kim Wookrae , Lee Myungjun
Published: August 2021

We present the hyperspectral imaging reflectometry technique for the critical dimension measurement of the advanced semiconductor devices. The proposed line scan based broadband system can enable high speed & non-destructive 3D measurements with great precision.
Inkjet Printed Optofluidic Biolasers for Laser Imaging Analysis of Living Organism
Authors: Gong Xuerui , Feng Shulin , Qiao Zhen , Yuan Zhiyi , Chen Yu-Cheng
Published: August 2021

An inkjet-printed biolaser microarray encapsulated with E.coli was developed, where laser emission images were employed for quantitative analysis. This work represents a milestone to implement biological microlaser technology towards high-throughput on-chip analysis of living organisms.
Photonics probing of probiotics effect on chronic alcoholic brain cell nuclei using light localization via confocal imaging
Authors: Adhikari Prakash , Shukla Pradeep K. , Rao Radhakrishna , Pradhan Prabhakar
Published: August 2021

We develop a probing method for molecular specific mass density fluctuations using light localization technique via confocal imaging. This work reports the effect of the probiotic in chronic alcoholic brain nuclei chromatin in a mouse model.
Multiheterodyne differential spectroscopy using dual-comb generation based on a dual-drive Mach Zehnder modulator
Authors: Poiana D.A. , Martín-Mateos P. , García-Souto J.A.
Published: August 2021

In this work, we present a system for performing spectroscopy measurements using a multimode multiheterodyne source generated with a dual-drive Mach Zehnder modulator and direct modulation over the seed laser. The system has been used to recover an absorption line shape of an HCN with far less setup complexity than other state-of-the-art approaches.
The Deepest Subwavelength LIPSS on ZnO by Reduction of the Damage Threshold
Authors: Liu Yaoyao , Wu Qiang , Yao Jianghong , Xu Jingjun
Published: August 2021

The smallest spatial period of LIPSS on ZnO monocrystal was achieved through metal/ZnO heterointerface assisted femtosecond laser processing. Simultaneously, the damage threshold of ZnO was decreased by 54% due to the metal film coating.
Intelligent Structure Monitoring for Tunnel Steel Loop Based on Distributed Acoustic Sensing
Authors: Hu Die , Tian Bin , Li Hao , Fan Cunzheng , Liu Tao , He Tao , Liu Yijie , Yan Zhijun , Sun Qizhen
Published: August 2021

A tunnel steel loop reinforcement invalidation monitoring technology based on optical fiber distributed acoustic sensing (DAS) is proposed and demonstrated. Assisted with machine learning, the identification accuracy rate of invalid degree is up to 97.8%.
Slope Assisted Brillouin Optical Time Domain Analysis Using Dual Frequency Probe with Gain and Loss Spectra
Authors: Saito Daiki , Tanaka Yosuke
Published: August 2021

We demonstrate a slope assisted Brillouin optical time domain analysis using dual frequency probe light amplified by Brillouin gain and attenuated by Brillouin loss, which generates linear output against temperature change.
Design of Nighttime Power Generation System to Optimally Utilize Outer Space Darkness
Authors: Fan Lingling , Li Wei , Jin Weiliang , Orenstein Meir , Fan Shanhui
Published: August 2021

We present a systematic optimization of nighttime thermoelectric power generation system utilizing radiative cooling. We show that an electrical power density > 2 W/m2, two orders of magnitude higher than previous works, is achievable using existing technologies.
Inverse Design Inspired VO2 Smart Window Film
Authors: Ouassal Hassna , Ren Han , Rebollo Steve , Li Jie , Arigong Bayaner
Published: August 2021

Inspired from inverse design methodology, a smart window film is designed utilizing VO2 material. The structure enables high visible, low near infrared transmittance and high visible and near infrared transmittance at high and low temperatures, respectively.
Phase-contrast-based holographic quantitative phase imaging by only two exposures
Authors: Hai Nathaniel , Rosen Joseph
Published: August 2021

Quantitative phase imaging using a new type of phase-shift holographic approach is demonstrated by capturing only two different phase-contrast images. Phase measurements with enhanced accuracy and optimal imaging characteristics for binary and biologic phase objects are provided.
Photonic Tuning of Silicon Ring Resonators Using an Automated Microfluidic Mixer
Authors: Carver Christian , Boaks Mawla , Kim JuHang , Larson Kevin , Nordin Gregory P. , Camacho Ryan M.
Published: August 2021

We demonstrate automated tuning of microring resonators using 3D-printed microfluidic control. We use a custom 3D-printer that is capable of printing devices with sub 10 µm features and automatic pumping, mixing, and dilution operations.
Enhanced photon absorption of Ge-on-Si avalanche photodiode with photon-trapping microstructure
Authors: Wu Shaoteng , Zhou Hao , Zhang Lin , Chen Qimiao , Hu Liangxing , Tan Chuan Seng
Published: August 2021

Ge-on-Si avalanche photodiodes with photon-trapping microstructure are designed and demonstrated to enhance the optical absorption. The responsivity is enhanced by 9-20% at the wavelength of 1,500-1,550 nm at -6V with the photon-trapping structures.
High Power MEMS Planar Light Valve
Authors: Liu Tianbo , Payne Alex , Hunter Jim , Jacob Gregory , Yamashita Satoshi , Myatt Greg , Eng Lars , Hashimoto Yoshimi , Mizuno Hirofumi , Fujisawa Yasumitsu , Hishitani Daisuke
Published: August 2021

The PLV supports modulation of over 500W of laser power for materials processing. It provides a line beam with 1088 individually addressable pixels and 200kHz switching speed. A custom optical head complements the PLV.
Ultrashort Pulse Induced Micro-explosion Time Resolved Dynamics in Bulk UV Fused Silica
Authors: Adnan Md Mohsinur Rahman , AlShafey Abdallah A. , Twardowski Justin , Talisa Noah , Tripepi Michael , Chowdhury Enam
Published: August 2021

Ultrafast dynamics of ultrafast single pulse induced micro-explosions in bulk fused silica was captured using.time resolved shadowgraphy. Experimental and theoretical considerations identify such micro-explosions creating warm dense matter (WDM) states.
Semi-Classical Description of Electron Dynamics in Solids Driven by Intense Laser Fields
Authors: Tani Mizuki , Otobe Tomohito , Shinohara Yasushi , Ishikawa Kenichi L.
Published: August 2021

We propose a Vlasov-LDA-based semi-classical approach for laser-driven electron dynamics in solids. We extend the pseudo particle method to periodic systems. The computation results agree excellently with the time-dependent density functional theory and experimental results.
Integrated Optical Phased Array for Temperature Sensing
Authors: Li Binghui , Sun Caiming , Wang Hongjie , Nie Xiaomin , Chen Zhenmin , Zhang Aidong
Published: August 2021

We report a simple concept to realize an optical phased array for temperature sensing. A maximum sensitivity of 0.0132 o/K was obtained at = λ1.45µ m. This work shows the promise of versatile OPA for optical sensing applications.
Synchronization of quantum communication systems based on correlated photons
Authors: Spiess Christopher , Töpfer Sebastian , Sharma Sakshi , Krzic Andrej , Sauer Gregor , Rieländer Daniel , Steinlechner Fabian
Published: August 2021

High-throughput quantum communication requires precise time tagging of photon detection events. Here we show how residual synchronization jitter as low as <1ps can be accomplished by autonomous correlation tracking of photon pairs, and discuss experimental results in a free-space link.
GeSn membrane mid-infrared photodetectors
Authors: Atalla Mahmoud R. M. , Assali Simone , Attiaoui Anis , Lemieux-Leduc Cédric , Kumar Aashish , Abdi Salim , Moutanabbir Oussama
Published: August 2021

Fully released Ge0.83Sn0.17 membranes are utilized in broadband photodetectors with a record wavelength cutoff of 4.6 μm and two orders of magnitude reduction in dark current as compared to as-grown strained epitaxial layers.
Plasmonic GeSn photodetectors for enhanced photo detection at 2 µm
Authors: Zhou Hao , Zhang Lin , Wu Shaoteng , Chen Qimiao , Son Bongkwon , Tan Chuan Seng
Published: August 2021

Gold hole-array nanostructure was incorporated into GeSn photodetectors to enhance the optical absorption at 2 μm. The surface plasmon resonance near Au/GeSn interface benefits a two times higher responsivity at 2 μm.
Widefield Super-sensitive Phase Imaging Using N00N State Illumination
Authors: Camphausen Robin , Cuevas Álvaro , Pruneri Valerio
Published: August 2021

We present a widefield quantum polarised light microscope, illuminating with a NOON state (N=2) and imaging using a SPAD array camera. Compared to classical imaging we show that sensitivity improves by a factor of 1.31.
Achromatic Broadband Visible Imaging with a 10cm Flat Lens
Authors: Meem Monjurul , Majumder Apratim , Banerji Sourangsu , Rodriguez Berardi Sensale , Menon Rajesh
Published: August 2021

We demonstrate 10 cm achromatic flat multilevel diffractive lens with a focal length and thickness of 200mm and 2.4 µm, respectively operating across the entire visible band, which is the largest flat lens ever reported till date.
Xenos peckii's Compound Eye Structure Inspired Flat Microlens Array for Super-resolution Imaging
Authors: Meem Monjurul , Majumder Apratim , Banerji Sourangsu , Rodriguez Berardi Sensale , Menon Rajesh
Published: August 2021

Inspired by compound eye structures found in insects, we demonstrate an ultrathin arrayed camera enabled by a flat multilevel diffractive microlens array for super-resolution visible imaging, with resolution improvement factor of 1.4 compared to the diffraction limit.
High-resolution artificial compound eye camera: a proof-of-concept study
Authors: Chang Sehui , Lee Gil Ju , Song Young Min
Published: August 2021

We suggest a new strategy for artificial compound eye camera using tapered fiber bundle. High-resolution imaging from curved microlens array is achieved, with vantages of natural insect eyes: wide field-of-view and infinite depth-of-field.
Optimized D-DFB laser diodes for the detection of trace gases in the MIR region
Authors: Hoppe Morten , Aßmann Christian , Schmidtmann Sebastian , Honsberg Martin , Milde Tobias , Sacher Joachim R.
Published: August 2021

An optimized D-DFB design is presented, which guarantees the best possible performance in the range from 1.9 µm to 4.5 µm. Results for the performance and its suitability for detecting trace gases are shown.
Atmospheric Carbon Dioxide Absorption Measurement using Integrated Lithium Niobate Nanophotonics
Authors: Zhang Jiuyi , Sua Yong Meng , Chen Jiayang , Ramanathan Jeevanandha , Tang Chao , Hu Yongxiang , Huang Yu-Ping
Published: August 2021

We use photon counting and a sweeping high-Q microring on chip to obtain the atmospheric carbon dioxide absorption spectrum around 1572.022 nm.
Near Infrared Photoimmunotherapy of Cancer
Authors: Kobayashi Hisataka
Published: August 2021

Near infrared photoimmunotherapy (NIR-PIT) is a molecularly-targeted cancer photo-therapy based on antibody-photoabsorber (IR700) conjugates. By crashing cancer cells combined with innate and/or adjuvant immune-activation, NIR-PIT activates anti-cancer immunity resulted in curing local and metastatic cancers.
Solid-state FMCW LiDAR based on a 2D disperser
Authors: Li Zhi , Zang Zihan , Liu Xuanyi , Wu Lican , Fu H. Y.
Published: August 2021

By employing a tunable laser and a 2D disperser, we experimentally realize a frequency-modulated continuous-wave lidar system that performs ranging and 2-dimensional non-mechanical beam-steering simultaneously. Reconfigurable high imaging resolution and precise ranging are achieved.
Characterization of Micromirrors Embedded in Parylene Photonic Waveguides for Out-of-plane Light Delivery
Authors: Reddy Jay W. , Malekoshoaraie Mohammad H. , Chamanzar Maysamreza
Published: August 2021

We have recently demonstrated flexible Parylene photonic waveguides with embedded micromirrors. Here, the out-of-plane beam profile of the micromirrors is characterized using a combination of simulation and experiments.
Fluorescence Imaging Technology for High-Power Laser Beam Profiling
Authors: Tsunekane M. , Takahashi T. , Yoshimori N. , Nakajima M.
Published: August 2021

Fluorescence imaging technology combined with a >2MW/cm2 damage threshold, fluorescent plate and a CMOS camera was developed for real-time 2D beam profiling of high-power lasers without any attenuators and any image reconstructions.
Room Temperature Planar Absolute Radiometer for High-Accuracy Optical Power Measurements
Authors: Vaskuri Anna K. , Stephens Michelle S. , Tomlin Nathan A. , Spidell Matthew T. , Yung Christopher S. , Walowitz Andrew J. , Straatsma Cameron , Harber David , Lehman John H.
Published: August 2021

We introduce a planar absolute radiometer for room temperature (PARRoT) that will replace NIST’s 50-year-old detector standard for free-space CW laser power measurements and lower the measurement uncertainty (k = 2) from 0.86% to 0.12%.
Resonant chalcogenide-metal-fluoropolymer nanograting for tunable pyroelectric sensing
Authors: Wei Le , Qian Jingjing , Dong Liang , Lu Meng
Published: August 2021

A resonant pyroelectric detector was demonstrated to support narrowband and tunable photopyroelectric effect in the near-infrared region. The narrowband pyroelectric device was built on a chalcogenide-metal-fluoropolymer (As2S3-Ag-PVDF) nanograting membrane, which was fabricated inexpensively using a solvent-assisted imprint lithography process. Under the resonant condition, the device exhibited a responsivity of 1.36 V/W. The device’s absorption and pyroelectric characteristics can be tuned using a bias voltage applied to the membrane.
Spectrally Gated Microscopy (SGM) with Flat Optics
Authors: Edrei Eitan , Weiss Aharon , Engelberg Jacob , Zektzer Roy , Levy Uriel
Published: August 2021

We introduce a new optical modality to enable three-dimensional imaging by rejecting out-of-focus light via spectral gating. Our modality doesn’t require axial physical scanning and can potentially achieve better sectioning capabilities than current state-of-the-art technology
Spontaneous Parametric Down Conversion in Linearly Uncoupled Resonators
Authors: Zatti Luca , Bergamasco Nicola , Lomonte Emma , Lenzini Francesco , Pernice Wolfram , Liscidini Marco
Published: August 2021

We study degenerate spontaneous parametric down conversion in a structure composed of two linearly uncoupled resonators, in which the linear properties of the fundamental and second harmonic field can be engineered independently.
Fully Integrated Electronic-Photonic Biosensor for Label-Free Molecular Sensing in Advanced Zero-Change CMOS-SOI Process
Authors: Adamopoulos Christos , Buchbinder Sidney , Zarkos Panagiotis , Bhargava Pavan , Gharia Asmaysinh , Niknejad Ali , Stojanovic Vladimir
Published: August 2021

We demonstrate the world's first fully integrated electronic-photonic label-free molecular sensor in a CMOS 45RFSOI commercial process. Real-time kinetics with 100nm lipid nanoparticles, mimicking SARS-CoV-2 particles, are presented utilizing micro-ring resonators integrated with on-chip electronics.
Photonic Resonator Interferometric Scattering Microscope for Single Molecule Characterization
Authors: Li Nantao , Canady Taylor D. , Huang Qinglan , Cunningham Brian T.
Published: August 2021

We developed photonic resonator interferometric scattering microscopy for the label-free detection of nano-objects at low illumination density using a non-immersion objective. Photonic crystals are utilized as the imaging substrates to enhance the intrinsic scattering signal.
Resolving partially coherent ultrafast pulses at the quantum limit
Authors: De Syamsundar , Gil-Lopez Jano , Brecht Benjamin , Silberhorn Christine , Sánchez-Soto Luis L. , Hradil Zdeněk , Řeháček Jaroslav
Published: August 2021

We demonstrate the precise measurement of the temporal delay between two partially coherent pulses at the quantum limit by projecting onto appropriate temporal modes. Our results confirm that mode projections are optimal for any degree of coherence.
Response of human induced pluripotent stem cells to terahertz radiation
Authors: Tachizaki Takehiro , Sakaguchi Reiko , Terada Shiho , Kamei Ken-ichiro , Hirori Hideki
Published: August 2021

Intense terahertz pulses were focused on cultured human induced pluripotent stem cells (hiPSCs) using newly developed apparatus. The THz irradiation experiments and gene analysis revealed that the genes in the hiPSCs that were affected by THz irra-diation were regulated zinc finger proteins. We also found that the housekeeping power and pluripotency were unaffected by intense THz pulses while several genes were up- and down-regulated.
Electro-optic tuning of non-Hermiticity in a silicon microring resonator
Authors: Lee Hwaseob , Soman Anishkumar , Li Tiantian , Kannaen Thomas , Mao Dun , Ozdemir Sahin K. , Gu Tingyi
Published: August 2021

We demonstrate a silicon photonic passive PT-symmetric structure operating at an exceptional point, with dynamic mode-splitting tunability enabled by a local heater.
Gold Nanorod Contrast-Enhanced Molecular Imaging of Choroidal Neovascularization using Dual Photoacoustic Ophthalmoscopy and Optical Coherence Tomography in a Rabbit Model
Authors: Nguyen Van Phuc , Li Yanxiu , Henry Jessica , Zhang Wei , Wang Xueding , Paulus Yannis M.
Published: August 2021

We present the potential of gold nanorods as a molecular contrast agent for multimodal photoacoustic ophthalmoscopy (PAOM) and optical coherence tomography (OCT) to visualize choroidal neovascularization in living rabbits.
All-Fiber Source and Sorter for Multimode Correlated Photons
Authors: Sulimany Kfir , Bromberg Yaron
Published: August 2021

We use spontaneous four wave mixing to generate multimode photon pairs in a few mode fiber. We show the photons are correlated in the fiber mode basis using an all-fiber mode sorter.
Observation of Thermal Biphotons
Authors: Lib Ohad , Bromberg Yaron
Published: August 2021

We present a novel type of incoherent light, thermal biphotons, that exhibit an Hanbury Brown and Twiss peak with a different width compared to classical thermal light, leading to the breakdown of the Siegert relation.
Understanding of ultrafast breathing-like dynamics in Ytterbium-doped fiber laser
Authors: Krupa Katarzyna , Kardaś Tomasz M. , Stepanenko Yuriy
Published: August 2021

We present experimental evidence of breathing-like dynamics in all-normal dispersion all-PM Ytterbium-doped fiber laser. The pulsation period oscillates with an increasing amplitude when pump power grows larger until a stationary dissipative soliton is formed.
Appropriate way to generate enough patterns for single pixel imaging using multicore fiber and photonic lantern
Authors: Xiang Yangyang , Li Ruoxuan , Li Junhui , Gao Li , Lan Mingying , Ma Jianxin
Published: August 2021

Numerical simulation recommends coherently illuminating multiple cores, other than increasing core number, as the way to get enough projecting patterns for high resolution single pixel imaging endoscopy using multicore fiber and photonic lantern.
High Responsivity MoSe2 Photodetector integrated in Si3N4 waveguide for quantum application
Authors: Gherabli Rivka , Indukuri S.R.K Chaitanya , Zektzer Roy , Frydendahl Christian , Mazurski Noa , Levy Uriel
Published: August 2021

We demonstrate experimentally an integrated photoconductor for visible frequencies based on MoSe2. We report a peak responsivity of ~30A/W for a wavelength of 780nm, which is ideal for on-chip integration with Rubidium atomic vapor.
Walking Solitons in Corrugated Waveguide
Authors: Dolinina Daria , Yulin Alexey
Published: August 2021

We study the dynamics of one-dimensional periodically modulated optical cavity driven by external coherent pump and demonstrate that because of the spontaneous symmetry breaking bifurcation in the system the walking solitons can appear.
Fabrication of Silver Coral-like AFM Probes for Tip- Enhanced Raman Spectroscopy by ICP-based approach
Authors: Capaccio Angela , Sasso Antonio , Rusciano Giulia
Published: August 2021

We describe a novel approach for the fabrication of plasmonic probes designed for Tip Enhanced Raman Spectroscopy (TERS) applications, based on the nano-structuration of Ag-coated commercial AFM probes via Inductively Coupled Plasma (ICP) discharge.
Ultrasoft Cavities with Giant Brownian Fluctuations
Authors: Douvidzon Mark , Chattopadhyay Udvas , Chong Yidong , Carmon Tal
Published: August 2021

Applying surfactants on submerged oil droplets permits resonators 10 orders of magnitude softer than what solids permit, with accordingly larger Brownian fluctuations. We measure a 150,000 quality factor, 6nm Brownian-fluctuation amplitude, and 155 Hz eigenfrequency.
Extreme Raman Red-Shift in Nitrogen-Filled Capillary Fibers
Authors: Piccoli R. , Carpeggiani P. A. , Jeong Y.-G. , Rovere A. , Morandotti R. , Coccia G. , Fan G. , Kaksis E. , Pugzlys A. , Baltuška A. , Schmidt B. E. , Voronin A. A. , Zheltikov A. , Razzari L.
Published: August 2021

By exploiting stimulated Raman scattering in long nitrogen-filled capillary fibers, we demonstrate continuous tunability of Yb laser systems over the 1.0-1.7 μm range, with conversion efficiency up to 82%, and an up to 10-fold pulse compression.
Bistability in Photonic Topological Insulators with Kerr Nonlinearity
Authors: Alharbi Ghada , Gong Yongkang , Wong Stephan , Oh Sang Soon
Published: August 2021

We propose a dynamic model for photonic topological insulators (PTIs) with Kerr nonlinearity. Using the model, we demonstrate the bistability and spontaneous symmetry breaking in the Su-Schrieffer-Heeger model and two-dimensional nonlinear PTIs.
An Alignment Procedure for Off-Axis Parabola Telescopes for High-Intensity Beam Transport
Authors: Ohland Jonas Benjamin , Eisenbarth Udo , Zielbauer Bernhard , Reemts Dirk , Bagnoud Vincent
Published: August 2021

Post-compressor beam transport becomes a challenge in Chirped Pulse Amplification lasers if a surface shall be imaged. We developed an easy and repeatable alignment procedure for off-axis parabola telescopes to fit these needs.
Photonic Transformers
Authors: Douvidzon Mark , Maayani Shai , Nagar Harel , Admon Tamir , VladimirShuvayev  , Yang Lan , Deych Lev , Roichman Yael , Carmon Tal
Published: August 2021

We report on transformable micro-photonic devices that change their functionality while operating. Assisted by holographic-tweezers, we gradually deform the shape of a droplet whispering-gallery cavity and split a resonant mode to a 10-GHz separated doublet.
Comb Formation In Ultrathin Terahertz Quantum Cascade Ring Lasers
Authors: Jaidl M. , Opačak N. , Kainz M. A. , Schönhuber S. , Theiner D. , Limbacher B. , Beiser M. , Giparakis M. , Andrews A. M. , Strasser G. , Schwarz B. , Darmo J. , Unterrainer K.
Published: August 2021

We present comb formation in ring-shaped THz quantum cascade lasers. Devices are spontaneously operating in a harmonic state transiting to a dense comb regime exhibiting over 30 equidistant modes covering a bandwidth of 622 GHz.
Titanium Dioxide as bio-sensor for local temperature detection
Authors: Zani Veronica , Pedron Danilo , Pilot Roberto , Signorini Raffaella
Published: August 2021

Aim of the present work is the realization of biocompatible optical thermometers. Raman measurements have been performed by exciting commercial anatase powder in the visible range, at defined temperature. Good reliable temperatures can be obtained.
Quality Control of Ethanol-Based Hand Sanitizer Gels in Micro-Opto-Fluidic Devices
Authors: Bello Valentina , Bodo Elisabetta , Merlo Sabina
Published: August 2021

We present a smart micro-opto-fluidic platform for quality control of ethanol-based hand sanitizer gels. Analyses rely on the study of the near infrared absorption features of fluids flowing in rectangular glass micro-capillaries with integrated reflectors.
Temporal Modulation of Powerful Bichromatic Femtosecond Laser Pulses in Air
Authors: Buozius Danas , Tamuliene Viktorija , Vaicaitis Virgilijus
Published: August 2021

We investigated third harmonic and terahertz radiation generation in air by bichromatic femtosecond laser pulses. Laser pulses experience a strong phase modulation and pulse splitting in air plasma, which affects third harmonic and terahertz signals.
Giant anisotropy in sub-micron vapor cells
Authors: Talker Eliran , Barash Yefim , Mazurski Noa , Levy Uriel
Published: August 2021

We demonstrate a giant light-induced anisotropy in sub-micron atomic vapor cells at elevated temperatures of ~250oC, showing a 1000-fold increase as compare with lower temperature ~150oC. The nanoscale thickness is crucial for observing this effect.
Pulse energy enhancement via filter shape optimization in an all-fiber Mamyshev oscillator
Authors: Poeydebat Etienne , Scol Florent , Vanvincq Olivier , Bouwmans Géraud , Hugonnot Emmanuel
Published: August 2021

We report on the experimental influence of filter shape on the dynamic of an all-fiber Mamyshev oscillator. Significant variation of output pulse energy and various regimes (harmonic mode-locking, multipulses) are observed.
Interference during high harmonic generation in solids via Van Hove Singularity effects
Authors: Kanai Tsuneto , Lee Yeon , Kim Dong Eon
Published: August 2021

We investigate the enhancement of high harmonics and relevant channels via the Van Hove singularity effect. The enhancement is efficient in a multi-photon regime, and the relevant quantum paths lead to interference of these channels.
Phase-insensitive Target Detection and Ranging Aided by Continuous-wave Photon-pair Sources
Authors: Han Liu , Helmy Amr S.
Published: August 2021

We demonstrate 26.3dB performance enhancement of phase-insensitive target detection and ranging resolution ' 5cm using continuous-wave photon pairs. The receiver operating characteristic analysis shows a detection-time reduction of 57 for fixed false- positive (10
−
6) and detection rates.
Broadband Directional Control of Thermal Emission
Authors: Xu Jin , Raman Aaswath P.
Published: August 2021

We experimentally realize broadband directional thermal emitters by introducing two subwavelength photonic structures consisting of multiple oxides that exhibit epsilon-near-zero (ENZ) regions at long-wave infrared wavelengths.
Membrane-based optomechanical accelerometry
Authors: Agrawal Aman R. , Chowdhury Mitul Dey , Pluchar Christian M. , Wilson Dalziel
Published: August 2021

Optomechanical accelerometers promise quantum-limited readout, high band- width, self-calibration, and radiation-pressure stabilization. We present a simple, scalable platform that enables these benefits with sub-µg sensitivity and 10 kHz bandwidth, based on a pair of vertically integrated SiN membranes.
A high accuracy cavity optomechanical accelerometer with electro-optic frequency comb readout
Authors: Long David A. , Reschovsky Benjamin J. , Zhou Feng , Bao Yiliang , Madugani Ramgopal , Allen Richard A. , Gorman Jason J. , LeBrun Thomas W.
Published: August 2021

A cavity optomechanical accelerometer based upon a Fabry-Pérot geometry is demonstrated. Electro-optic frequency combs are employed as a rapid and high accuracy method to interrogate a cavity mode and elucidate the corresponding acceleration.
Anti-parity-time-symmetric integrated optical gyroscopes
Authors: De Carlo Martino , De Leonardis Francesco , Passaro Vittorio M. N.
Published: August 2021

Parity-time-symmetric optical gyroscopes are gaining interest for the enhanced sensitivity shown by exceptional points. The real splitting of anti-PT-symmetric gyroscopes is more reliable for stability and readout scheme than the complex splitting of parity-time-symmetric gyroscopes.
Electrical Switching of Nonvolatile Phase-Change Materials for Integrated Photonics: a Comparison
Authors: Zheng Jiajiu , Fang Zhuoran , Zhu Shifeng , Xu Peipeng , Dunham Scott , Majumdar Arka
Published: August 2021

We compare electrical switching of nonvolatile phase-change materials for integrated photonics with graphene, ITO, and silicon p−i−n heaters. Graphene heaters exhibit the best heating and overall performance with high switching speed (~80 MHz) and energy efficiency (6.6 aJ/nm3).
Carrier dynamics in nitrogen-doped graphene under THz radiation
Authors: Anvari Roozbeh , Dignam Marc M.
Published: August 2021

Nitrogen is a common impurity in graphene. We combine density functional tight binding theory and a density matrix formalism to calculate the effect of nitrogen doping on the linear and nonlinear carrier dynamics in graphene.
Machine LearningAnalysisof 2×1 VCSEL ArrayCoherence and ImaginaryCouplingCoefficient
Authors: Strzebonski Pawel , North William , Jahan Nusrat , Choquette Kent D.
Published: August 2021

Machine learning is used to estimate the coherent-coupling power enhancement from 2 × 1 VCSEL arrays and serves to identify coherent non-Hermitian operation.
Manifold Learning for Reducing the Design Complexity of Photonic Nanostructures
Authors: Zandehshahvar Mohammadreza , Kiarashi Yashar , Zhu Muliang , Maleki Hossein , Brown Tyler , Adibi Ali
Published: August 2021

We present a new manifold-learning-based approach to reduce the geometric complexity of the inverse design of photonic nanostructures and show how this approach can provide valuable insight about the underlying physics of their operation.
New approach to mode locking of high-energy-pulse fibre lasers
Authors: Nyushkov B. , Ivanenko A. , Smirnov S. , Kobtsev S.
Published: August 2021

A new mode locking fibre laser configuration is proposed that delivers record-high energy (150 nJ) of short linearly polarised pulses (~ 200 ns) without external amplification. It is further shown that such performance may be achieved by elongation of the laser cavity with a standard PM-fibre.
Control of VCSEL polarization via built-in gratings
Authors: Qiu Pingping , Wu Bo , Fu Pan , Li Ming , Xie Yiyang , Kan Qiang
Published: August 2021

Polarization control of VCSEL via built-in gratings is demonstrated. Compared with the devices without gratings, the VCSEL with built-in gratings exhibits a higher orthogonal polarization suppression ratio (>18 dB) up to thermal rollover.
On scattering-induced fading in underwater FSO links for clear ocean and coastal waters
Authors: Salcedo-Serrano Pedro , Boluda-Ruiz Rubén , Garrido-Balsells José María , García-Zambrana Antonio
Published: August 2021

We propose a novel probability density function to describe statistically the effect of scattering-induced fading in underwater FSO links for clear ocean and coastal waters, achieving a coefficient of determination R2 above 0.9.
Study on Optical Efficiency of CMOS Image Sensor to High Performance Imaging Devices
Authors: Cho Hyo Jong , Do Yun Seon
Published: August 2021

In this study, we designed the CMOS image sensor and performed optical analysis. As a result, our suggested structure is 19.5% (red), 3.2% (green) and 14.6% (blue) improvements over the reference structure.
Erbium-doped dual wavelength fiber laser interferometric proximity sensor with ± 16 nm measurement accuracy
Authors: Tian Zhen , Chen Nan-Kuang , Shum Perry Ping , Yao Cheng-Kai , Zhang Liqiang , Yao Yicun , Grattan Kenneth T. V. , Ren Shijie , Wu Qiang
Published: August 2021

An erbium-doped fiber ring laser proximity sensor with a high accuracy of ±16 nm, when the output power difference between the dual lasing wavelengths (~1560 nm) is smaller than 3 dB wavelength has been demonstrated.
Coupling Scaling for High-efficient Cnoidal Wave Generation in Microresonators
Authors: Wang Pei-Hsun , Chiang Kuan-Lin
Published: August 2021

We model the threshold and efficiency of microcombs by scaling the cavity coupling with the Lugiato-Lefever equation (LLE) and the traveling wave theory. Stable cnoidal waves with efficiency ≥ 40% are analytically identified at over-coupling.
Development of Low Noise III-V Digital Alloys for Improved Photodetection
Authors: Ahmed Sheikh Z. , Zheng Jiyuan , Tan Yaohua , Campbell Joe C. , Ghosh Avik W.
Published: August 2021

A detailed theoretical investigation of the underlying physics of low noise III-V digital alloy APDs is presented here. Based on our investigations, the criteria for developing low noise digital alloys are proposed.
UV Laser Pulse Trains for Raman Spectroscopy
Authors: Swanson Dustin , Sprangle Phillip
Published: August 2021

The theoretical framework for Raman spectroscopy using a UV probe laser pulse train consisting of multi femtosecond pulses is developed. We show selective excitation of a single Raman mode by tuning the pulse parameters.
Arrival Time Monitor for Sub-10 fs Soft X-ray and 800 nm Optical Pulses
Authors: Muhammad Isa Shams , Frimpong Benson , Daafour Joseph , Xu Xiaoqing , Walter Peter , Wolf Thomas J. A. , Cryan James P. , Glownia James M. , Robinson Joseph S. , Droste Stefan , Coslovich Giacomo
Published: August 2021

We develop an Arrival Time Monitor (ATM) achieving high sensitivity for soft X-ray pulses in low-fluence conditions. The ATM cross-correlates ultrashort X-ray with 800nm laser pulses using a new multi-layer target designed and grown in-house to achieve optimal sensitivity.
Efficient Broadly Tunable Waveguide Lasers in Yb3+:CaF2 Produced by Deep Diamond Saw Dicing
Authors: Loiko Pavel , Gauthier-Manuel Ludovic , Brasse Gurvan , Braud Alain , Benayad Abdelmjid , Camy Patrice
Published: August 2021

High-aspect-ratio ridge waveguides (propagation losses: 0.13±0.05 dB/cm) were fabricated in Yb3+:CaF2 by diamond-saw-dicing. The waveguide laser generated 723 mW at 1029-1051 nm with a slope efficiency of 76.0%; wavelength tuning between 1009-1072 nm was achieved.
Physical Unclonable Functions Based on Holographic Microstructures on Silver
Authors: Anastasiou Angeliki , Zacharaki Evangelia I. , Tsakas Anastasios , Moustakas Konstantinos , Alexandropoulos Dimitris
Published: August 2021

We demonstrate the utilization of Computer-Generated Holograms engraved on silver surface with a nanosecond infrared fiber laser as ultra-strong optical PUFs. The reconstructed images represented through a few distinctive features could create robust authentication keys.
Terahertz Waves Polarization Rotation in Unaligned Single-Wall Carbon Nanotubes
Authors: Kvitsinskiy Anatoly , Demchenko Petr , Novoselov Mikhail , Anoshkin Ilya , Bogdanov Kirill , Baranov Alexander , Khodzitsky Mikhail
Published: August 2021

Faraday effect modulation in carbon nanotubes was experimental studied in range 0.2–0.8 THz with a weak magnetic field. A change of 15° in an azimuth, and of 10° in an ellipticity angle was achieved.
Investigation of the plume generated in LIBS process induced by a ps UV laser
Authors: Rastegari Ali , Diels Jean-Claude
Published: August 2021

The plume produced by a ps UV laser is analyzed, with the aim of understanding the ultra-narrow (isotopically resolvable) re-absorption lines that we observed with this type of irradiation.
Free-form Broadband Flat Lens for F-Number and Numerical Aperture Decoupling
Authors: Meem Monjurul , Majumder Apratim , Banerji Sourangsu , Rodriguez Berardi Sensale , Menon Rajesh
Published: August 2021

The f-number (f#) and numerical aperture (NA) of a conventional lens are inherently coupled. We demonstrate a free-form broadband flat lens that de-couples the f# and NA.
Coherent Manipulation of Finite-Energy Gottesman-Kitaev-Preskill-Qubit Graph States
Authors: Seshadreesan Kaushik , Dhara Prajit , Patil Ashlesha , Jiang Liang , Guha Saikat
Published: August 2021

We present an exact description of graph states composed of finite-energy Gottesman-Kitaev-Preskill qubits, and determine rules for their transformation under Steane error correction and fusion operations that can be used to grow large graph states.
A Self-Oscillating Phase Conjugate Resonator as an Optical Frequency Comb
Authors: Zhou Zhifan , Zhao Jie , Spiers Rory W. , Brewer Nicholas , Wu Meng-Chang , Lett Paul D.
Published: August 2021

We demonstrate a phase conjugate resonator with a forward-propagating four-wave mixing process that oscillates with the build-up of spontaneous emission. The oscillation exhibits frequency comb properties: equal frequency spacing and phase coherence among different components.
Free-Electron Interactions with Designed van der Waals Materials: Novel Source of Lensed X-ray Radiation
Authors: Shi Xihang , Shentcis Michael , de Abajo Javier García , Kaminer Ido
Published: August 2021

We propose two novel X-ray generation schemes based on free electron interactions with van der Waals materials, in which the crystal geometry is shaped to create intrinsic lensing of the generated X-rays.
Infrared beam steering device based on InAsSb/(Al)GaInSb heterostructure
Authors: Liu Jinghe , Kucharczyk Kevin , Donetsky Dmitri , Kipshidze Gela , Belenky Gregory , Svensson Stefan P.
Published: August 2021

We describe an nBp structure comprised of waveguide with gratings for electronic steering a 10.6-µm laser and show that a 0.06 change of the refractive index by carrier injection leads to a 3.5° steering angle.
Far-Subwavelength Spatial Resolution Using Relative Motion in Structured Illumination
Authors: Raghuram Vivek , Hastings Ryan L. , Webb Kevin J.
Published: August 2021

Far-subwavelength spatial resolution based on relative motion between a struc- tured field and an object with far-field intensity measurements is proposed, supported with numerical simulations, and demonstrated with speckle from random media to sense mi- crostructure.
Measuring Luttinger Parameters Directly from Quasiparticle Dynamics
Authors: O’Hara Seamus , Costello Joe , Wu Qile , West Ken , Pfiffer Loren , Sherwin Mark
Published: August 2021

High-order sideband generation (HSG) is sensitive to dynamic phases, which electrons and holes accumulate when accelerating through a III-V semiconductor. This sensitivity can be exploited to reconstruct the effective Hamiltonian through HSG polarimetry.
Dielectric Metasurfaces made of Vertically Oriented Germanium Ellipses
Authors: Gennaro Sylvain D. , Goldflam Michael , Burckel D. Bruce , Jeong Jeeyoon , Sinclair Michael , Brener Igal
Published: August 2021

In this work, we investigate the linear optical response of a dielectric metasurface made of vertically-oriented germanium ellipses deposited on walls of a micron-scale cubic silicon nitride unit cell support matrix.
Light by Design: Engineering 2D Optical Fields in Inhomogeneous Media
Authors: Aborahama Yousuf , Mojahedi Mo
Published: August 2021

We provide a generalized theoretical framework for designing optical fields with arbitrarily chosen intensity and phase patterns inside an inhomogeneous media. We demonstrate the capabilities of our formulation by generating two exotic beam patterns.
Optical Vortex Memory
Authors: Eshaghi Mahdi , Dogariu Aristide
Published: August 2021

We demonstrate that, upon interaction with different randomly scattering media, vortex beams maintain a certain memory of initial properties. We describe the extent of this memory in relation to variance and spatial correlation of randomness
Ultra-high Q Silica Microcavity Fabrication Using Conventional Photolithography Combined with Chemo-Mechanical Polishing
Authors: Honari Shahin , Haque Sanaul , Lu Tao
Published: August 2021

We fabricated ultrahigh Q silica microdisks using conventional photolithog- raphy followed by chemo-mechanical polishing. Through this procedure, optical quality factor exceeding one hundred million was obtained.
Enhanced supercontinuum from a dispersion-varying fiber
Authors: Alamgir Imtiaz , Shamim Md Hosne Mobarok , Correr Wagner , Messaddeq Younès , Rochette Martin
Published: August 2021

We experimentally demonstrate that a supercontinuum becomes further broadened by using a dispersion varying nonlinear medium. Compared to constant dispersion designs, a power enhancement of 4.3 dB and bandwidth extension of 262 nm are obtained.