bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficient production of mycosporine-like amino acids, natural sunscreens, in Yarrowia lipolytica
Authors: Jin Hyunbin , Kim Sojeong , Lee Daeyeol , Ledesma-Amaro Rodrigo , Hahn Ji-Sook
Published: October 2023

Background

Mycosporine-like amino acids (MAAs), including shinorine and porphyra-334, are gaining attention as safe natural sunscreens. The production of MAAs has been achieved in diverse microbial hosts, including Saccharomyces cerevisiae. While S. cerevisiae is the most extensively studied model yeast, the oleaginous yeast Yarrowia lipolytica has emerged as a promising candidate for the synthesis of valuable products. In this study, we explored the potential of Y. lipolytica as a host for producing MAAs, utilizing its advantages such as a robust pentose phosphate pathway flux and versatile carbon source utilization.

Results

We produced MAAs in Y. lipolytica by introducing the MAA biosynthetic genes from cyanobacteria Nostoc punctiforme and Anabaena variabilis. These genes include mysA, mysB, and mysC responsible for producing mycosporine-glycine (MG) from sedoheptulose 7-phosphate (S7P). The two strains utilize different enzymes, D-Ala-D-Ala ligase homologue (MysD) in N. punctiforme and NRPS-like enzyme (MysE) in A. variabilis, for amino acid conjugation to MG. MysE specifically generated shinorine, a serine conjugate of MG, while MysD exhibited substrate promiscuity, yielding both shinorine and a small amount of porphyra-334, a threonine conjugate of MG. We enhanced MAAs production by selecting mysA, mysB, and mysC from A. variabilis and mysD from N. punctiforme based on their activities. We further improved production by strengthening promoters, increasing gene copies, and introducing the xylose utilization pathway. Co-utilization of xylose with glucose or glycerol increased MAAs production by boosting the S7P pool through the pentose phosphate pathway. Overexpressing GND1 and ZWF1, key genes in the pentose phosphate pathway, further enhanced MAAs production. The highest achieved MAAs level was 249.0 mg/L (207.4 mg/L shinorine and 41.6 mg/L of porphyra-334) in YP medium containing 10 g/L glucose and 10 g/L xylose.

Conclusions

Y. lipolytica was successfully engineered to produce MAAs, primarily shinorine. This achievement involved the introduction of MAA biosynthetic genes from cyanobacteria, establishing xylose utilizing pathway, and overexpressing the pentose phosphate pathway genes. These results highlight the potential of Y. lipolytica as a promising yeast chassis strain for MAAs production, notably attributed to its proficient expression of MysE enzyme, which remains non-functional in S. cerevisiae, and versatile utilization of carbon sources like glycerol.
Conservator-Restorer | Current Status of the Profession in Portugal
Authors: Reis David Teves
Published: November 2023

On the 2022 E.C.C.O. - European Confederation of Conservator-Restorers’ Organizations - General Assembly and President’s Meeting at Athens, Greece, the cradle of democracy and oratory, the representatives of the European associations of Conservators-Restorers gathered, on the prospect of showing an overview of the current status of the profession in each country. ECCO challenged the professional associations to address the national legal framework of conservation-restoration in each country, debating the “Achievements and directions in the Þeld of Conservation-Restoration for the sustainable development of Cultural Heritage”, so we, in behalf of the ARP Board President, Rui Borges, had the opportunity to pinpoint the challenges and future prospects on the profession in Portugal and what has been the evolution of the association’s work over the last few years, hoping for a pan European recognition of the uniqueness of the conservator-restorer profession and its important and central role within the cultural heritage sector, not only for its sole beneÞt but for the beneÞt of all that it represents. Amidst the evidence that, for the time being, there is no European-wide solution that is applicable in the speciÞc legal and training context of each country, together, the European associations of Conservators-restorers are treading the path of success and, at this moment, everyone counts. The congregating role of E.C.C.O. becomes essential to navigate among the various European legal frameworks and identify the working tools that guarantee the placement of the regulation of the profession in the national and international policy agendas. Working and collaborating in a network, the successes that each association achieves are reßected in a global process. The present paper translates what was presented at the Meeting, to understand the current status of the Portuguese Conservators-Restorers.
A Methodological Approach to Justifying Royalty Rates in Projects of Oil and Gas Companies
Authors: Bykov D. , Kazakova Anna , Alaberdin Renat
Published: October 2023

Intellectual property (IP) is the result of the creative work of inventors. The implementation of intellectual property and non-property rights is regulated by Russian law. One of the important components of intellectual property (IP) management is its commercialization. It is possible to assess the value of IP through an objective analysis of projects and their parameters, including financial components. Commercialization of IP is carried out through the mechanisms of alienation and disposal by companies of their intellectual assets in order to obtain commercial benefits. One of the ways to dispose of rights is to conclude license agreements on granting the right to use protected intellectual property. The validity of a license agreement depends on the presence in the compensated license agreement of a condition on the amount and procedure for paying remuneration. Payment of remuneration may be provided in the form of one-time payments (lump payment), periodic interest deductions (royalties) or in another form. Payments in the form of royalties are most in the interests of the right holder. The calculation of the royalty rate is methodologically not regulated at the legislative level and is the most controversial issue when concluding license agreements. The development of methodological approaches to determining the royalty rate makes it possible to increase the justification of the costs of project implementation. The article describes the existing methodological approaches to the calculation of a fair royalty rate, analytical tools for determining standard royalty rates, and the values of recommended royalty rates in the oil and gas industry.
Risks of Default in the Context of Financial Globalization Processes and Deglobalization Effects
Authors: Ryaskova E. , Ryaskov N.
Published: October 2023

The article examines the evolutionary development of financial globalization the process, the rising processes of deglobalization, transformation of the world order and the impact of these processes on the financial stability of countries. Current events show that the world order is being transformed, the structure and mechanisms of the global economy are changing. There is a qualitative change in the competitive environment and differentiation of states in the global space. In the article particular attention is paid to the situation with the alleged “default” of the Russian Federation on its obligations to foreign investors caused by sanctions in 2022. The possible consequences of the voluntary blocking of payments by creditors are considered and the effect of these events on economic, financial and monetary policy in Russia are analyzed.
Too Much Information: When Does Additional Testing Benefit Schools?
Authors: Virudachalam Vanitha , Savin Sergei , Steinberg Matthew P.
Published: November 2023

U.S. K–12 school districts that traditionally utilized ongoing “formative” assessments of student progress increasingly rely on additional “interim” assessments to predict student performance on standardized tests. Moreover, some districts are experimenting with merit-based teacher bonuses tied to standardized test scores. We examine the relationship between interim assessments and teacher bonuses using a two-period principal–agent model. The school district (principal), operating under a limited budget, decides whether to implement interim assessments and how much merit pay to offer, and teachers (agents) choose how much effort to exert in each period. We use two-state (proficient versus not proficient) Markovian dynamics to describe the evolution of student test readiness, in which the transition probability in a given period depends on both teachers’ effort decisions and the starting state. Our results indicate that, despite the popularity of interim assessments, their usefulness is far from guaranteed. In particular, the accuracy promised by these assessments is a double-edged sword: positive midyear results can make it easier to incentivize second period teacher effort, but negative results can have a demotivating effect. Moreover, even when an interim assessment does result in a higher probability of the school ending the year in the proficient state, the resulting higher expected costs of merit-based bonuses for the district may exceed the available budget. Thus, even a free interim assessment might be too expensive for the school district.

This paper was accepted by Charles Corbett, operations management.

Funding: This research was supported by the Risk Management Center Russell Ackoff Doctoral Student Fellowship and the Fishman-Davidson Center for Service and Operations Management, both at The Wharton School, University of Pennsylvania, Philadelphia, Pennsylvania.

Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2020.01547 .
Quantitative Mineralogical Analysis and Study of Morphology and Thermal Characteristics of Rock Samples of Dudhi Nala and Bokaro River.
Authors: Mahato Omprakash , Srivastava P. K.
Published: November 2023

Beds of Talchir formation are well exposed in the western part of the Bokaro coalfields (Dudhi Nala) which comprises tillite, conglomerates, sandstones, with dropstones and turbidite sequences comprising siltstones and shales. This work presents the study of glacigenic Talchir sediments of Dudhi Nala section and sediments of Bokaro river. The morphology, major oxides, trace elements, Rare Earth elements and minerals found in these sediments are of great geological importance. The minerals present in these samples have been also investigated. The samples collected from Dudhi Nala are enriched in SiO2 (66-68 wt % compared to 25-60 wt % in the samples of Bokaro river). In contrast to SiO2, Fe2O3 is dominant in the Bokaro river samples. Dudhi Nala samples are rich in trace elements like Ba (1047 ppm), Rb ( 219 ppm), Sr (312 ppm), Zr ( 256 ppm) and Pb (65 ppm), where as Bokaro river samples dominates in Cr (140 ppm), Sc (39 ppm), V (117 ppm) and Zn (90 ppm). FESEM/ EDX analysis was done to study the morphological characteristics and elemental composition were analysed by FESEM/EDX. Thermal characteristics of the samples were studied by TGA/DSC. Further, XRD analysis confirmed that Calcite and feldspar are the common minerals present in the samples of the both the study areas.
Awareness and attitudes regarding oral care intervention program based on community care for older adults at home: focusing on the grounded theory
Authors: Park Myeong-Hwa , Park Ji-Won , Lee Seul-Ah , Jang Jong-Hwa
Published: October 2023

Objectives: This study is based on a visiting oral health care intervention program in the community care. This qualitative study was conducted through in-depth interviews to identify awareness and attitudes regarding intervention program among older adults. Methods: The research team visited the homes of the target older adults and conducted in-depth interviews for approximately an hour using a semi-structured questionnaire. The collected voice recordings were transcribed using Clova Note, and AI program by Naver. Using the ‘Word Cloud Generator 3.7’ program, words of high importance and interest from interview answers were extracted, visualized, and analyzed. Results: Participating older adults acknowledged that their quality of life related to oral health could be improved by increasing the level of oral health awareness and oral health knowledge through the intervention program. In addition, the older adults indicated that their oral hygiene management ability improved compared to before the intervention through expert oral hygiene management and oral health education. Further, as the level of oral health knowledge increased, so too did satisfaction with the intervention program increase. Conclusions: The intervention program for visiting oral health care showed a positive effect on the awareness and attitude of older adults. Thus, it is suggested that education for continuous competency enhancement of dental hygienists and multidisciplinary education for the improvement of general health and quality of life of older adults should be promoted.
Effects of subjective oral and mental health on health-related quality of life (EQ-5D) in cancer survivors: The 8th Korea National Health and Nutrition Examination Survey (8th KNHANES, 2019-2020)
Authors: Jung Eun-Seo
Published: October 2023

Objectives: This study aimed to prepare basic data to improve the health-related quality of life of cancer survivors by confirming their oral and mental health statuses and identifying factors affecting their health-related quality of life. Methods: Of all participants in the 8th KNHANES (2019–2020), adults aged 19 years or older who responded ‘yes’ to the diagnosis of cancer and 404 cancer survivors who responded ‘none’ to the current cancer prevalence item were selected as the final research participants. Multiple regression analysis was conducted to confirm the effect of cancer survivors’ oral and mental health on health-related quality of life. Results: Subjective oral health (p<0.01), chewing problems (p<0.05), subjective health (p<0.001), and depression (p<0.01) had an effect on health-related quality of life from multiple regression analyses. Conclusions: Therefore, oral and mental health promotion may improve health-related quality of life. Thus, it is necessary to recognize the importance of oral and mental health and implement preventive education and programs.
Big boned: How fat storage and other adaptations influenced large theropod foraging ecology
Authors: Pahl Cameron C. , Ruedas Luis A.
Published: November 2023

Dinosaur foraging ecology has been the subject of scientific interest for decades, yet much of what we understand about it remains hypothetical. We wrote an agent-based model (ABM) to simulate meat energy sources present in dinosaur environments, including carcasses of giant sauropods, along with living, huntable prey. Theropod dinosaurs modeled in this environment (specifically allosauroids, and more particularly, Allosaurus Marsh, 1877) were instantiated with heritable traits favorable to either hunting success or scavenging success. If hunter phenotypes were more reproductively successful, their traits were propagated into the population through their offspring, resulting in predator specialists. If selective pressure favored scavenger phenotypes, the population would evolve to acquire most of their calories from carrion. Data generated from this model strongly suggest that theropods in sauropod-dominated systems evolved to detect carcasses, consume and store large quantities of fat, and dominate carcass sites. Broadly speaking, selective forces did not favor predatory adaptations, because sauropod carrion resource pools, as we modeled them, were too profitable for prey-based resource pools to be significant. This is the first research to test selective pressure patterns in dinosaurs, and the first to estimate theropod mass based on metabolic constraints.
Kerala Kalamandalam: A legacy revisited
Authors: Viswanathan Kaladharan
Published: November 2023

The performance landscape of Kerala is diverse, and its history hails the glory of Kutiyattam, the sole surviving Sanskrit theatre tradition in India; Kathakali, the classical dance-drama; and Mohiniyattam, an exclusive female dance form. This is in addition to a huge variety of ritual and folk performance forms all over the region. While the first onstage recital of Kutiyattam performance and the subsequent development of its aesthetics and criticism date back to tenth and eleventh century AD, the entire Kathakali repertory originated and developed in the seventeenth century. On the other hand, Mohiniyattam seems to have originated even later. As a residential training centre for traditional performing arts in Kerala, Kalamandalam facilitated intense and uninterrupted communications amongst the top-ranking artists of various art forms. The Second World War had its devastating effects on the cultural institutions in India in general, and Kalamandalam in particular. Then, the Department of Education, Government of India, took over the administration of Kalamandalam. In 1976, Kalamandalam became a grant-in-aid institution under the Charities Registration Act and started functioning under a General Council and Executive Board constituted by the Government of Kerala. In 2006, Kalamandalam was deemed to be a university, functioning under the Cultural Affairs Department, Government of Kerala. The main objective of the institutional transformation was to combine practical training in different performing arts at the academic level. Several groups of students are now coming out of Kalamandalam every year after successfully completing their graduate and postgraduate programmes. Advanced training programmes are held at the Nila Campus in Cheruthuruthy, while the undergraduate courses are offered at the sprawling Vallathol Nagar Campus.
Atención al nacimiento durante la pandemia COVID-19: restricciones al acompañamiento y cuidados de las madres infectadas
Authors: Ferrándiz Mares Claudia , Llinares Ramal Sandra , Seguí Manzaneque Sandra , Pérez López Alba Isabel , Segura Barrachina Sara , Jareño Roglán Enrique Jesús , Albert i Ros Xavier
Published: November 2023

Introducción: Los primeros protocolos respecto a la atención al parto y las restricciones de aforo por la pandemia COVID-19 se han relacionado con prácticas no deseables: impedir el acompañamiento en el parto, acelerar el expulsivo, separar madre e hijo o posponer la lactancia materna. El objetivo de este trabajo es valorar la medida en que se han podido dar estas situaciones en nuestro país.
Pacientes y Métodos: 1321 madres que dieron a luz entre marzo de 2019 y mayo de 2021. Estudio descriptivo retrospectivo, basado en encuestas en forma de formularios on-line, sobre infección por SARS-CoV-2, acompañamiento en el parto, forma de dar a luz, alojamiento conjunto y alimentación del bebé.
Resultados: Observamos un significativo incremento del obstáculo al acompañamiento en el parto a partir del 14 de marzo de 2020: 19 %, respecto al 5 % previo (p < 0.001). Entre las madres infectadas por SARS-CoV-2 (17), el 71 % no pudieron estar acompañadas frente al 18 % en las madres no infectadas (p < 0.001); en 3 casos se ha inducido o instrumentado el parto para acelerar el expulsivo y en otros 3 se ha separado a los bebés de sus madres y se les ha alimentado con sucedáneos en la Maternidad.
Conclusiones: Durante la pandemia se ha producido un incremento significativo del impedimento al acompañamiento al parto, significativamente mayor en las madres infectadas por SARS-CoV-2; también hemos detectado entre madres infectadas varios casos de inducción o instrumentación para acelerar el expulsivo, y de separación y empleo de sucedáneos.
Look Who's Talking
Authors: Glazer Amanda , Luo Hubert , Devgon Shivin , Wang Catherine , Yao Xintong , Yao Steven Siwei , McQuarrie Frances , Li Zelin , Palma Adalie , Wan Qinqin , Gu Warren , Sen Avi , Wang Zihui , O'Connell Grace D. , Stark Philip B.
Published: November 2023

The "job talk"is a standard element of faculty recruiting. How audiences treat candidates for faculty positions during job talks could have disparate impact on protected groups, including women. We annotated 156 job talks from five engineering and science departments for 13 categories of questions and comments. All departments were ranked in the top 10 by US News & World Report. We find that differences in the number, nature, and total duration of audience questions and comments are neither material nor statistically significant. For instance, the median difference (by gender) in the duration of questioning ranges from zero to less than two minutes in the five departments. Moreover, in some departments, candidates who were interrupted more often were more likely to be offered a position, challenging the premise that interruptions are necessarily prejudicial. These results are specific to the departments and years covered by the data, but they are broadly consistent with previous research, which found differences of comparable in magnitude. However, those studies concluded that the (small) differences were statistically significant. We present evidence that the nominal statistical significance is an artifact of using inappropriate hypothesis tests. We show that it is possible to calibrate those tests to obtain a proper P-value using randomization.
Sustainability and Operational Excellence opportunities with Industry 4.0, Lean and Circular Economy
Authors: Caiado Rodrigo Goyannes Gusmão , Nascimento Daniel Luiz de Mattos , Maqueira Juan Manuel , Tortorella Guilherme Luz , Vieira Neto Julio
Published: October 2023

We are delighted to present this comprehensive editorial note summarizing the seven papers published in response to our Call for Papers on "When Titans Meet – Industry 4.0, Lean, and Circular Economy opportunities towards operational excellence and sustainability." This special issue aimed to explore the convergence of Industry 4.0 (I4.0), Lean Management (LM), and Circular Economy (CE) practices and their implications for achieving sustainability in various domains. The papers selected for this special issue provide valuable insights into this evolving field. [...]
Transition metal-based materials and their catalytic influence on MgH2 hydrogen storage: A review
Authors: Gbenebor Oluwashina Philips , Popoola Abimbola Patricia Idowu
Published: October 2023

The dependence on fossil fuels for energy has culminated in its gradual depletion and this has generated the need to seek alternative source that will be environmentally friendly and sustainable. Hydrogen stands to be promising in this regard as energy carrier which has been proven to be efficient. Magnesium hydride (MgH2) can be used in storing hydrogen because of its availability, light weight and low cost. In this review, monoatomic, alloy, intermetallic and composite forms of Ti, Ni, V, Mo, Fe, Cr, Co, Zr and Nb as additives on MgH2 are discussed. Through ball milling, additive reacts with MgH2 to form compounds including TiH2, Mg2Ni, Mg2NiH4, V2O, VH2, MoSe, Mg2FeH6, NbH and Nb2O5which remain stable after certain de/hydrogenation cycles. Some monoatomic transition metals remain unreacted even after de/hydrogenation cycles. These formed compounds, including stable monoatomic transition metals, impart their catalytic effects by creating diffusion channels for hydrogen via weakening Mg - H bond strength. This reduces hydrogen de/sorption temperatures, activation energies and in turn, hastens hydrogen desorption kinetics of MgH2. Hydrogen storage output of MgH2/transition metal-based materials depend on additive type, ratio of MgH2/additive, ball milling time, ball –to combining materials ratio and de/hydrogenation cycle. There is a need for more investigations to be carried out on nanostructured binary and ternary transition metal-based materials as additives to enhance the hydrogen storage performance of MgH2.  In addition, the already established compounds (listed above) formed after ball milling or dehydrogenation can be processed and directly doped into MgH2.
Peroxynitrite-Induced Intracellular Ca2+ Depression in Cardiac Myocytes: Role of Sarco/Endoplasmic Reticulum Ca2+ Pump
Authors: Flores-Tamez V. , Escalante B. , Rios Amelia
Published: October 2023

Several studies have shown that peroxynitrite (ONOO–), formed upon the reaction of •NO and O2–, is increased in many cardiovascular diseases and is detrimental to myocardial function. Proteins associated with Ca2+ homeostasis regulation in the heart may be involved in these effects. Thus, the aim of this study was to elucidate the mechanisms associated with ONOO–-induced effects. We evaluated [Ca2+]i regulation, sarco/endoplasmic reticulum Ca2+- binding proteins, and phosphorylation levels of the ryanodine receptor in isolated rat myocytes. Electrical field-induced intracellular Ca2+ transients and contractions were recorded simultaneously. Myocytes superfused with 3-morpholinosydnonimine N-ethylcarbamide (SIN-1), an ONOO– donor, decreased the amplitude of Ca2+ transients and contraction in a dose-response (1–200 μM) manner. Similarly, SIN-1 increased half-time decay in a concentration-dependent manner. Co-infusion of the ONOO– donor with FeTMPyP (1 μM), an ONOO– decomposition catalyst, inhibited the effects induced by ONOO–. Impaired sarcoplasmic reticulum Ca2+ uptake caused by ONOO– (SIN-1 200 μM) was confirmed by a reduction of caffeine-evoked Ca2+ release along with prolongation of the half-time decay. Surprisingly, ONOO– induced a spontaneous Ca2+ transient that started at the beginning of the relaxation phase and was inhibited by tetracaine. Also, reduced phosphorylation at the ryanodine receptor 2 (RyR2)-Ser-2814 site was observed. In conclusion, deficient sarco/endoplasmic reticulum Ca2+-ATPase-mediated Ca2+ uptake concomitant with augmented Ca2+ release by RyR2 in myocytes may be associated with modification of myocyte Ca2+ handling by ONOO–. Thus, development of cardiac failure in diabetes, nephropathy, or hypertension may be related with elevated ONOO– in cardiac tissue.
Estimation of water consumption and productivity for wheat using remote sensing and SEBAL model: A case study from central clay plain Ecosystem in Sudan
Authors: Turk Khalid G. Biro , Alsanad Mohammed A.
Published: November 2023

Remote sensing (RS) can efficiently support the quantification of crop water requirements and water productivity (WP) for evaluating the performance of agricultural production systems and provides relevant feedback for management. This research aimed to estimate winter wheat water consumption and WP in the central clay plain of Sudan by integrating remotely sensed images, climate data, and biophysical modelling. The wheat crop was cultivated under a centre-pivot irrigation system during the winter season of 2014/2015. The Landsat-8 satellite data were used to retrieve the required spectral data. The Surface Energy Balance Algorithm for Land (SEBAL) was supported with RS and climate data for estimating the Actual Evapotranspiration (ETa) and the WP for the wheat crop. The SEBAL outputs were validated using the FAO Penman–Monteith method coupled with field measurements and observation. The results showed that the seasonal ETa ranged from 400 to 600 mm. However, the WP was between 1.2 and 1.5 kg/m3 during the wheat cycle. The spatial ETa and WP maps produced by the SEBAL model and Landsat-8 images can improve water use efficiency at field scale environment and estimate the water balance over large agricultural areas.
Effectiveness of stego images pre-processing withspectral analysis methods
Authors: Progonov Dmytro O. , Lutsenko Volodymyr M.
Published: November 2023

Early detection of sensitive data leakage during message transmission in communication systems is topical task today. This is complicated by applying of attackers to advanced steganographic methods. Feature of such methods is sensitive information embedding into innocuous (cover) files, such as digital images. This drastically reduces effectiveness of modern stegdetectors based on applying of signature and statistical steganalysis methods. There are proposed several approaches for improving detection accuracy of stegdetectors that are based on image pre-processing(calibration). These methods are aimed at estimation parameters either of stego, or coverimages from current analysed image.The first group of calibration methods requires prior information about features of used embedding methods to minimize detection error. In most cases, this information is limited that decrease effectiveness of such calibration methods. The second group of calibration methodsis of special interest today due to extensive set of proposed methods for advanced image denoising techniques. Nevertheless, practical usage of such methods requires carefully adjustment of parameters.Thisrestrictsfast re-training of stegdetector for revealing stego images formed according to unknown embedding methods.Thepromising approach for estimation cover image parameters from current (noisy) images is based on applying of novel methods of spectral analysis, namely sparse and redundant representationof signals. Featureof these methods is ability to adjust parameters of basicfunctions to statistical parameters of analysed set of image. This allows improving effectiveness of stegdetectors without necessity to re-tune theirs parameters for new set if images. The paper is aimed at performance analysis of stego images pre-processing with usage of advanced methods of spectral analysis. The analysis was performed for state-of-the-art HUGO embedding methods by usage of standard ALASKA dataset. Based on obtained results, it was revealed that applying of proposedmethods allows improving detection accuracyup to 6%even in case of absence prior information about used embedding methods and low cover image payload, e.g.less than 10%. Nevertheless, practical usage of thesemethods for image calibration requires further improvement of dictionary learningprocedure, namely decreasing its computation complexity byprocessing images with high resolution.
Cancellation Of Seizure Of Property At The Stage Of Pre-Trial Investigation As An Element Of Due Legal Procedure
Authors: Shvydkova O.V. , Svoiak D.V.
Published: November 2023

In the article, with the aim of researching the legal and practical model of cancellation of property seizure in criminal proceedings at the stage of pre-trial investigation and determining ways of their improvement, it is emphasized that the institution of cancellation of property seizure in criminal proceedings is a necessary element of the observance of the fundamental rights guaranteed by the Constitution of Ukraine and the Convention for the Protection of Human Rights and Fundamental Freedoms regarding the restoration of the right to peaceful possession of property, in which the state intervened during the investigation of the criminal proceedings, which were closed.Considered topical issues of the procedure for canceling the seizure of property during the pre-trial investigation in case of closing the criminal proceedings by the investigator or inquirer. The ways of canceling the arrest imposed on property within the framework of criminal proceedings during the pre-trial investigation are highlighted.It is pointed out the unequal judicial practice regarding the solution of this issue, which was regulated by the adoption of a resolution by the Grand Chamber of the Supreme Court. Further changes in the legislation regarding the termination of the decisions of the investigating judge on the application of measures to ensure the criminal proceedings, which include the seizure of property, after the closure of the criminal proceedings, despite the fact that they should have changed judicial practice, but did not have a significant impact.Attention is focused on different ways of interpreting the procedural norm regarding the powers of the prosecutor to cancel the seizure of property upon closing the criminal proceedings, one of which empowers the prosecutor to issue a resolution on the cancellation of the seizure of property, even if the criminal proceedings are closed by the decision of the investigator, inquirer.The necessity of streamlining judicial practice and legislation, which regulates the procedure for keeping registers of encumbrances of property rights, is indicated. A conclusion was made regarding the need to improve the procedure for canceling the seizure of property in criminal proceedings in terms of introducing a mechanism for automatic restoration of the rights of the owner (possessor) of such property.
Copyrights for official works created by scientific and pedagogical workers
Authors: Myronenko I.V. , Heints R.M.
Published: November 2023

The article is devoted to the research of regulatory approaches regarding the copyright of scientific and pedagogical workers on official works in connection with the adoption of the new Law of Ukraine «On Copyright and Related Rights» on December 1, 2022. In the work, a comparative analysis of the definition of the concept of «official work» under current legislation with the legislation that was in force until January 1, 2023 was carried out, it was determined which works created by scientific and pedagogical workers are subject to the legal regime of official work.It has been established that the current legislation enshrines the presumption of ownership of property rights of a higher education institution for an official work created by a scientific and pedagogical employee. If there is no provision for changing this presumption in the employment contract (contract), then this can be done by concluding a civil law contract, the parties of which are the institution of higher education and the scientific and pedagogical worker. A conclusion was made about the need to supplement the employment contract (contract) with a condition regarding the property rights of the scientific and pedagogical worker to official works. Attention is drawn to the fact that today the subject of copyright can use the sign of legal protection (©) only to indicate his property rights. The conducted research does not exhaust all problematic aspects of the research topic. We see the prospect of its further study in solving questions, related to the implementation of copyright in this area.
What's In the PR Pipeline?
Authors: Pavlin T
Published: November 2023

October is Eye Health Month, a time when related organizations naturally develop campaigns to help educate the public about vision care and related issues. Many of these efforts take place around World Sight Day, which falls in 2006 on Thursday, Oc­tober 12th.
Who Should be Taking Care of Children's Eyes?
Authors: Michaud Langis , Mercier Marie-Eve , Deschamps Marie-Josee
Published: November 2023

The purpose of this study was to survey a population in the Montreal area (Quebec, Canada) for its opinion concerning the importance of making children's first eye examinations legally mandatory before the children start school.
Choriorétinopathie séreuse centrale associée à l’administration de l’erdafitinib : Rapport de cas
Authors: Blanchard Sierra , Li Suzzane , Weiler Danielle
Published: November 2023

L'erdafitinib est un inhibiteur de kinase du récepteur du facteur de croissance des fibroblastes (FGFR) qui a été approuvé pour le traitement des patients atteints de carcinome urothélial métastatique ou localement avancé. Il est également à l'étude pour le traitement d'autres types de cancer. Cet agent chimiothérapeutique oral fait l'objet d'une mise en garde concernant les effets indésirables oculaires potentiels, notamment la rétinopathie séreuse centrale et la sécheresse oculaire liées au traitement. Ce rapport de cas décrit un homme caucasien de 88 ans qui a été pris en charge par la clinique ophtalmologique au cours d'un traitement par erdafitinib pour un carcinome urothélial métastatique. Le patient a développé des épisodes asymptomatiques de rétinopathie séreuse centrale bilatérale récurrente et rémittente liée au traitement. Il est essentiel que les fournisseurs de soins oculaires reconnaissent les effets indésirables oculaires potentiels liés à l'erdafitinib, à sa classe de médicaments et aux médicaments qui ciblent des voies similaires.  Une communication efficace et une cogestion attentive avec l'oncologie sont essentielles pour fournir des soins de qualité à ce sous-ensemble de patients. Grâce à la coordination des soins, une posologie efficace, mais tolérable peut offrir au patient un meilleur taux de survie et une meilleure qualité de vie.
Rock Typing and Characterization of the Late Cretaceous Abu Roash "G" Reservoirs at East Alam El-Shawish Field, Western Desert, Egypt
Authors: Sabry Marwan M. , Abdel-Fattah Mohamed I. , El-Shafie MohamedMohamed K.
Published: November 2023

Rock typing and petrophysical characterization play a vital role in constructing reservoir models for petroleum exploration and development. This study focuses on evaluating the petrophysical characteristics of the Late Cretaceous Abu Roash "G" Reservoirs at the East Alam El Shawish field in Egypt's Western Desert. The study involved five vertical wells and employed various techniques and analyses to investigate the reservoir. Lithology determination utilizing well logs and core analysis helps identify the lithology types and corresponding porosity of the Abu Roash "G" reservoirs. Sandstone and limestone lithologies with varying porosity ranges were identified, along with the influence of shale on neutron porosity values. Facies analysis of the Abu Roash "G" Member identified seven lithofacies types, categorized into shallow marine and deeper marine depositional environments. The petrophysical analysis involves evaluating gamma-ray logs, porosity, permeability, flow zone indicator (FZI), and reservoir quality index (RQI) values for each lithofacies type. This analysis classifies the core samples into seven reservoir rock types (RRT1 to RRT7) based on petrophysical attributes, providing a clear classification of the Abu Roash "G" reservoir interval. RRT1, RRT2, and RRT3 exhibit the highest reservoir quality, while RRT4 and RRT5 indicate moderate reservoir quality. RRT6 and RRT7 exhibit low reservoir quality due to unfavorable petrophysical behavior. The findings of this study provide valuable insights into the Abu Roash "G" reservoir, including its lithofacies, reservoir properties, and depositional environments. This knowledge is crucial for reservoir characterization and optimizing oil production strategies in the region.
Teaching the basics of technique and development of coordination abilities of judokas of 6-7 years old with the help of fitball exercises
Authors:   Kharkiv State Academy of Physical Culture, Lomizov V. , Boychenko N. ,   Kharkiv State Academy of Physical Culture
Published: November 2023

Purpose: to increase the effectiveness of teaching the basics of technique and development of coordination abilities of judokas of 6-7 years old by means of exercises with fitballs. Material and methods. The following methods were used in the research: theoretical analysis and generalization of literary sources; pedagogical supervision over the educational and training process; pedagogical experiment; pedagogical testing; method of expert estimations; methods of mathematical statistics. Results: it is proposed to use exercises with fitballs aimed at studying the basics of technique and development of coordination abilities that corresponds to the age of 6-7 years (exercises with fitballs for studying acrobatic exercises, for studying the basics of self-insurance, for fixing the technique of unbalancing, for studying the technique of throwing over the hip and back foot, exercises for developing balance). After the experiment judokas of the experimental group improved the most significantly the scores for the performance of a roll over the right (t=3,04; p<0,05) and left shoulder (t=3,59; p<0,05), self-insurance on the right (t=3,90; p<0,05) and left side (t=3,38; p<0,05), forward balance (t=3,21; p<0,05), forward-left (t=3,21; p<0,05) and forward-right (t=3,63; p<0,05). When comparing indicators of development of coordination abilities of the control and experimental groups with each other a statistically significant difference in indicators of Romberg test (t=2,89; p<0,05) and jumps with revolutions (t=2,39; p<0,05) characterizing the level of static and dynamic balance was established. When comparing the scores between judokas of the control and experimental groups, a statistically significant difference was also found (t=3,20; p<0,05), which indicates a greater effectiveness of the means of the sportsmen of the experimental group. When performing a throw over the hip at the end of the pedagogical experiment there is a statistical increase of scores for the performance of a throw in sportsmen of the experimental group (t=4,16; p<0,05). Comparing the scores between judokas of the control and experimental groups the statistically significant difference (t=3,05; p<0,05) is also established, that indicates the greater efficiency of means of sportsmen of the experimental group which improved indicators connected with the performance of technical actions forward, such as removal from balance and throw over a hip. Conclusions. It is experimentally established that with the help of the offered means it is possible to teach effectively such difficult technical actions as self-insurance on the right and left side, unbalancing forward, forward-side, throw back foot, throw over a thigh, to develop static and dynamic balance, also they will allow to improve the performance of technical actions in both directions
Integration of children with autism spectrum disorders in schools and the role of the occupational therapist
Authors:   CSSDM (Montreal School Service Center), Danova Olga
Published: November 2023

This article analyzes the problem of school integration of children with autism spectrum disorder in neurotypical (normal) conditions and the role of an occupational therapist. In addition, it focuses on the identification of intervention methods that facilitate this process, based on an analysis of the scientific literature and personal professional experience
Study of the lower limbs in congenital arthrogriphosis in children under the influence of rehabilitation measures
Authors:   Kharkiv State Academy of Physical Culture, Kuznetsova Victoria , Kalmykova Yuliya ,   Kharkiv State Academy of Physical Culture, Kalmykov Serhii ,   Kharkiv State Academy of Physical Culture
Published: November 2023

The article presents the etiology and pathogenesis of the disease according to ICD 10, determination of disorders according to IFF-DP, evaluation of the results of goniometry, VAS, muscle strength according to L.D. Potekhinim and Khabirov, manual testing of muscles by Lovett in congenital arthrogryposis of the lower extremities in children under the influence of the author's program of physical therapy: muscle-energy techniques, soft tissue techniques and articulation techniques.
Use of international scales for diagnosis and evaluation of the effectiveness of rehabilitation of children with cerebral palsy
Authors:   National University of Pharmacy, Petrenko Anastasia , Tamozhanska Ganna ,   National University of Pharmacy
Published: November 2023

The research considered the use of international scales for diagnosis and evaluation of the effectiveness of rehabilitation when working with children diagnosed with cerebral palsy (CP), namely the Classification of major motor functions and the Scale of major motor functions, modified Ashfort scale and modified Tardier scale , International Classification of Functioning, Restriction of Life and Health of Children and Adolescents; the sections of the Classification of Large Motor Functions and the Scale of Large Motor Functions, the International Classification of Functioning, Restriction of Life and Health of Children and Adolescents have been studied in detail; comparatively modified Ashfort scale and modified Tardier scale; the peculiarities of the use and relevance of selected international scales in the field of physical therapy are analyzed.
Training equipment for sports games
Authors:   Sumy State University, Ostapenko Yurii , Serhiіenko Volodymyr ,   Sumy State University
Published: November 2023

Growing requirements for the quality of training of specialists in game sports dictate the involvement of new approaches to the construction and organization of the educational and training process. The expediency of using training simulators in game sports is considered, their specific orientation and rationality of use are described. The purpose coverage of training equipment aimed at improving the physical and technical training of higher education students in sports games classes. Results of the research.The analysis of scientific and methodical literature, the Internet information network made it possible to determine that training equipment is a powerful tool in sports games. The review of information sources indicates the positive impact of simulators in the process of physical education and professional training in sports games of students of higher education institutions. It was found that the use of training equipment allows you to significantly shorten the training period, allows you to selectively influence the development of motor skills, take into account the individual level of physical development and physical fitness of each student, improve the quality of technical training, simulate motor actions, and monitor various types of athlete training. Examples of training equipment are given, the purpose of their purpose and the method of their use are described. Conclusions. The quality of performance of a wide range of technical and tactical techniques requires a review of the content, forms and methods of conducting initial training sessions on sports games. The updating of traditional means and the involvement of training equipment will allow to qualitatively increase the effectiveness of the educational process, both in physical education and in the training of future specialists in the field of physical culture and sports.
Наказ №227 «Ні кроку назад» у повсякденній культурі страху сталінізму
Authors: Щелкунов Антон
Published: November 2023

У спадкоємиці сталінського СРСР – путінської Росії через художні псевдоісторичні твори зобразили штрафбат як сакральний простір у якому кримінальні злочинці перетворюються на справжніх героїв, ціль життя яких вбивати і померти на війні без жодної раціональної мети. Оспівування штрафних підрозділів у сучасній Росії стало однією із основ формування мілітаристської ідеології окупантів, яким все одно за що вмирати і кого вбивати.

Метою дослідження є з’ясування ролі штрафних формувань Червоної армії в роки Другої Світової війни в утвердженні повсякденної культури страху серед радянських людей.

Результати. Розглянуто основні положення наказу № 227, проаналізовано його місце в повсякденній культурі страху. На основі спогадів ветеранів Другої Світової війни показано як страх визначав їх поведінку під час війни та їх ставлення до наказу № 227 вже після її завершення.

Висновки. Сталін і його оточення шукали нові методи посилення повсякденного страху. Результатом цих пошуків стало видання Наказу № 227, «Ні кроку назад» і створення штрафних частин. З того моменту повсякденну культуру страху серед військовослужбовців підпитували не тільки загрози розстрілу чи ув’язнення, а ще й нова форма покарання, яка передбачала залишатися на фронті в значно гірших умовах, адже штрафників не розквартировували у населених пунктах, гірше годували і відправляли на самі важкі ділянки фронту. Тому, Наказ № 227 і штрафні підрозділи слід розглядати не тільки суто з точки зору військової доцільності, а ще з точки зору культурного феномену, який скорегував радянську повсякденність під час Другої Світової війни. Радянська людина повинна була відчувати, що сталінська тоталітарна держава значно сильніша і страшніша за гітлерівську. Цей культурний феномен породив міф про штрафбат, який став частиною ідеології сучасної путінської Росії, в якій штрафбат асоціюється не з жертвами війни і сталінізму, а з кримінальними злочинцями-рецидивістами, які готові вбивати і гинути на війні.