bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioengineered Nanoparticles Loaded-Hydrogels to Target TNF Alpha in Inflammatory Diseases
Authors: Oliveira Isabel Matos , Fernandes Diogo Castro , Maia Fátima Raquel , Canadas Raphael Faustino , Reis Rui Luís , Oliveira Joaquim Miguel
Published: July 2021

Rheumatoid Arthritis (RA) is an incurable autoimmune disease that promotes the chronic impairment of patients’ mobility. For this reason, it is vital to develop therapies that target early inflammatory symptoms and act before permanent articular damage. The present study offers two novel therapies based in advanced drug delivery systems for RA treatment: encapsulated chondroitin sulfate modified poly(amidoamine) dendrimer nanoparticles (NPs) covalently bonded to monoclonal anti-TNF α antibody in both Tyramine-Gellan Gum and Tyramine-Gellan Gum/Silk Fibroin hydrogels. Using pro-inflammatory THP-1 (i.e., human monocytic cell line), the therapy was tested in an inflammation in vitro model under both static and dynamic conditions. Firstly, we demonstrated effective NP-antibody functionalization and TNF-α capture. Upon encapsulation, the NPs were released steadily over 21 days. Moreover, in static conditions, the approaches presented good anti-inflammatory activity over time, enabling the retainment of a high percentage of TNF α. To mimic the physiological conditions of the human body, the hydrogels were evaluated in a dual-chamber bioreactor. Dynamic in vitro studies showed absent cytotoxicity in THP-1 cells and a significant reduction of TNF-α in suspension over 14 days for both hydrogels. Thus, the developed approach showed potential for use as personalized medicine to obtain better therapeutic outcomes and decreased adverse effects.
Targeted Liposomes Encapsulating miR-603 Complexes Enhance Radiation Sensitivity of Patient-Derived Glioblastoma Stem-Like Cells
Authors: Shabana Ahmed M. , Xu Beibei , Schneiderman Zachary , Ma Jun , Chen Clark C. , Kokkoli Efrosini
Published: July 2021

Despite potential for clinical efficacy, therapeutic delivery of microRNAs (miRNA) remains a major translational barrier. Here, we explore a strategy for miRNA delivery in the treatment of glioblastoma, the most common form of adult brain cancer, that involves complexation of miRNA with polyethylenimine (PEI) and encapsulation in targeted liposomes. miRNA 603 (miR-603) is a master regulatory miRNA that suppresses glioblastoma radiation resistance through down-regulation of insulin-like growth factor 1 (IGF1) signaling. miR-603 was complexed with PEI, a cationic polymer, and encapsulated into liposomes decorated with polyethylene glycol (PEG) and PR_b, a fibronectin-mimetic peptide that specifically targets the α5β1 integrin that is overexpressed in glioblastomas. Cultured patient-derived glioblastoma cells internalized PR_b-functionalized liposomes but not the non-targeted liposomes. The integrin targeting and complexation of the miRNA with PEI were associated with a 22-fold increase in intracellular miR-603 levels, and corresponding decreases in IGF1 and IGF1 receptor (IGF1R) mRNA expression. Moreover, treatment of glioblastoma cells with the PR_b liposomes encapsulating miR-603/PEI sensitized the cells to ionizing radiation (IR), a standard of care treatment for glioblastomas. These results suggest that PR_b-functionalized PEGylated liposomes encapsulating miR-603/PEI complexes hold promise as a therapeutic platform for glioblastomas.
Efficient Deep-Blue Electroluminescence Employing Heptazine-Based Thermally Activated Delayed Fluorescence
Authors: Li Jie , Zhang Jincheng , Gong Heqi , Tao Li , Wang Yanqing , Guo Qiang
Published: July 2021

We report an efficient deep-blue organic light-emitting diode (OLED) based on a heptazine-based thermally activated delayed fluorescent (TADF) emitter, 2,5,8-tris(diphenylamine)-tri-s-triazine (HAP-3DPA). The deep-blue-emitting compound, HAP-3DPA, was designed and synthesized by combining the relatively rigid electron-accepting heptazine core with three electron-donating diphenylamine units. Due to the rigid molecular structure and intramolecular charge transfer characteristics, HAP-3DPA in solid state presented a high photoluminescence quantum yield of 67.0% and obvious TADF nature with a short delayed fluorescent lifetime of 1.1 μs. Most importantly, an OLED incorporating HAP-3DPA exhibited deep-blue emission with Commission Internationale de l’Eclairage (CIE) coordinates of (0.16, 0.13), a peak luminance of 10,523 cd/m−2, and a rather high external quantum efficiency of 12.5% without any light out-coupling enhancement. This finding not only reports an efficient deep-blue TADF molecule, but also presents a feasible pathway to construct high-performance deep-blue emitters and devices based on the heptazine skeleton.
Comparison of a Vintage and a Recently Released Nematicide for the Control of Root-Knot Nematodes and Side Effects on Two Entomopathogenic Nematodes
Authors: Giannakou Ioannis O. , Kamaras Stefanos
Published: July 2021

Root-knot nematodes can cause tremendous losses in vegetable crops. Farmers usually rely on synthetic nematicides to protect their crops. Recently, newly released nematicides are giving farmers an alternative in chemical control for nematodes. In the present study, the efficacy of vintage nematicide was compared to that of a relatively new nematicide, fluopyram. The latter was always more effective in substantially lower concentrations than oxamyl. Fluopyram paralyzed more than 80% J2s after 24 h immersion at the concentration of 0.25 μL L−1, while the percentage was increased close to 100% after immersion for 48 and 96 h. Similar levels of dead J2s were observed after immersion of J2s in oxamyl at concentrations higher than 8 μL L−1 (24 and 48 h) or 4 μL L−1 (96 h). An evident decrease of egg differentiation was observed when fluopyram concentration was increased to 8 μL L−1, while no significant decrease in egg differentiation was recorded at any concentration of oxamyl. Egg hatching was decreased at concentrations of fluopyram higher than 4 μL L−1, while no reduction was observed even when the concentration of oxamyl was increased to 64 μL L−1. The efficacy of fluopyram in soil was superior compared to that of oxamyl. For the first time, the systemic action of fluopyram is recorded in trials with tomato plants. On the other hand, compared to oxamyl, fluopyram seems to be more toxic to non-target organisms such as the entomopathogenic nematodes Steinernema feltiae and Heterorhabditis bacteriophora.
Self-Assembled Membrane-like Nanomaterials from Sequence-Defined Peptoid Block Copolymers
Authors: Wei Tiantian , Wu Jingjing , Shen Xiran , Qiu Zhifeng , Guo Li
Published: July 2021

Sequentially defined membrane-like nanomaterials have potential applications in biomedical and chemical fields due to their unique physical and chemical properties. However, these natural and synthetic nanomaterials have not been widely developed due to their complicated molecular sequence and structure, difficulties in synthesis etc. Here, we report a stable membrane-like nanomaterial composed of a monolayer or bilayer that was self-assembled from sequence-defined amphiphilic peptoid triblock (poly(N-aminoethyl glycine)-b-poly(N-octyl glycine)-b-poly(N-carboxyethyl glycine)) and diblock (poly(N-carboxyethyl glycine)-b-poly(N-octyl glycine) and poly(N-aminoethyl glycine)-b-poly(N-octyl glycine)) copolymers separately. A series of peptoid block copolymers were synthesized, and it was observed that long alkyl side chains and abundant hydrophobic blocks were necessary to form the membranes. The prepared membrane-like nanomaterials were fairly stable. They did not change obviously in shape and size with time, and they can survive after sonication. This study is expected to enrich the nanomaterial family, as well as polypeptoid science, and expand their applications in biomedicine and other fields.
An Innovative Computational Strategy to Optimize Different Furnish Compositions of Tissue Materials Using Micro/Nanofibrillated Cellulose and Biopolymer as Additives
Authors: Morais Flávia P. , Carta Ana M. M. S. , Amaral Maria E. , Curto Joana M. R.
Published: July 2021

The furnish management of tissue materials is fundamental to obtain maximum quality products with a minimum cost. The key fiber properties and fiber modification process steps have a significant influence on the structural and functional properties of tissue paper. In this work, two types of additives, a commercial biopolymer additive (CBA) that replaces the traditional cationic starch and micro/nanofibrillated cellulose (CMF), were investigated. Different formulations were prepared containing eucalyptus fibers and softwood fibers treated mechanically and enzymatically and both pulps with these two additives incorporated independently and simultaneously with drainage in the tissue process range. The use of these additives to reduce the percentage of softwood fibers on tissue furnish formulations was investigated. The results indicated that a maximum of tensile strength was obtained with a combination of both additives at the expense of softness and water absorbency. With a reduction of softwood fibers, the incorporation of additives increased the tensile strength and water absorbency with a slight decrease in HF softness compared with a typical industrial furnish. Additionally, a tissue computational simulator was also used to predict the influence of these additives on the final end-use properties. Both additives proved to be a suitable alternative to reduce softwood fibers in the production of tissue products, enhancing softness, strength and absorption properties.
Hemostatic Patches Based on Crosslinked Chitosan Films Applied in Interventional Procedures
Authors: Lee Moon Hyun , Lee Dae Ryeong , Chon Joon Woo , Chung Dong June
Published: July 2021

In this study, we manufactured biocompatible hemostatic crosslinked chitosan (CS) patches and analyzed their physicochemical and biological properties for femoral arterial puncture applications. CS is a representative hemostatic material but has some drawbacks, such as swelling, shrinkage, and brittleness. Thus, it was crosslinked via a 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC)/N-hydroxysuccinimide (NHS) coupling reaction and a nucleophilic addition reaction with citric acid (CA), glutaraldehyde (GTA), and genipin (GP) to remedy its shortcomings. The CSCA (crosslinked CS with CA/EDC), CSGTA (crosslinked CS with GTA), and CSG (crosslinked CS with GP) films showed low swelling degrees and good mechanical properties (excluding CSCA) compared with those of neat CS films. Additionally, every crosslinked CS film coated with thrombin (TB-CS) showed enhanced hemostatic ability in the whole blood clotting and activated partial thromboplastin time tests. Furthermore, the CSCA, CSGTA, and CSGP were nontoxic in an in vitro cell cytotoxicity test (3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide assay) using L-929 mouse fibroblasts cells.
Improvement of the UV Barrier and Antibacterial Properties of Crosslinked Pectin/Zinc Oxide Bionanocomposite Films
Authors: Hari Karina Dyasti , Garcia Coralia V. , Shin Gye-Hwa , Kim Jun-Tae
Published: July 2021

Pectin-based antibacterial bionanocomposite films were prepared by crosslinking with calcium chloride (CaCl2) and mixing with zinc oxide nanoparticles (ZnO-NPs) at various concentrations (0.5%, 1%, and 1.5% w/w, based on pectin). Crosslinking with 1% CaCl2 significantly (p < 0.05) improved the tensile strength of the pectin films, although their elongation at break was decreased. The UV-light barrier property of the pectin/ZnO bionanocomposite films was significantly (p < 0.05) improved with increasing ZnO-NP concentrations. In addition, the bionanocomposite films incorporating 1.5% ZnO-NPs showed excellent antibacterial effects against both Escherichia coli and Staphylococcus aureus, inhibiting over 99% of the bacteria. Therefore, the developed crosslinked pectin/ZnO bionanocomposite films show great potential as active packaging materials with excellent UV-blocking and antibacterial properties.
Going Beyond the Carothers, Flory and Stockmayer Equation by Including Cyclization Reactions and Mobility Constraints
Authors: De Keer Lies , Van Steenberge Paul H. M. , Reyniers Marie-Françoise , D’hooge Dagmar R.
Published: July 2021

A challenge in the field of polymer network synthesis by a step-growth mechanism is the quantification of the relative importance of inter- vs. intramolecular reactions. Here we use a matrix-based kinetic Monte Carlo (kMC) framework to demonstrate that the variation of the chain length distribution and its averages (e.g., number average chain length xn), are largely affected by intramolecular reactions, as mostly ignored in theoretical studies. We showcase that a conventional approach based on equations derived by Carothers, Flory and Stockmayer, assuming constant reactivities and ignoring intramolecular reactions, is very approximate, and the use of asymptotic limits is biased. Intramolecular reactions stretch the functional group (FG) conversion range and reduce the average chain lengths. In the likely case of restricted mobilities due to diffusional limitations because of a viscosity increase during polymerization, a complex xn profile with possible plateau formation may arise. The joint consideration of stoichiometric and non-stoichiometric conditions allows the validation of hypotheses for both the intrinsic and apparent reactivities of inter- and intramolecular reactions. The kMC framework is also utilized for reverse engineering purposes, aiming at the identification of advanced (pseudo-)analytical equations, dimensionless numbers and mechanistic insights. We highlight that assuming average molecules by equally distributing A and B FGs is unsuited, and the number of AB intramolecular combinations is affected by the number of monomer units in the molecules, specifically at high FG conversions. In the absence of mobility constraints, dimensionless numbers can be considered to map the time variation of the fraction of intramolecular reactions, but still, a complex solution results, making a kMC approach overall most elegant.
A Simple Approach to Produce Tailor-Made Chitosans with Specific Degrees of Acetylation and Molecular Weights
Authors: Sánchez Luis-Felipe , Cánepa Jimmy , Kim Suyeon , Nakamatsu Javier
Published: July 2021

Chitin is a structural polysaccharide that is found in crustaceans, insects, fungi and some yeasts. Chitin deacetylation produces chitosan, a well-studied biopolymer with reported chemical and biological properties for diverse potential applications for drug delivery, metal ion absorption, scaffolds and tissue engineering. Most known properties of chitosan have been determined from samples obtained from a variety of sources and in different conditions, this is, from chitosans with a wide range of degrees of N-acetylation (DA) and molecular weight (MW). However, as for any copolymer, the physicochemical and mechanical characteristics of chitosan highly depend on their monomer composition (DA) and chain size (MW). This work presents a simple methodology to produce chitosans with specific and predictive DA and MW. Reaction with acetic anhydride proved to be an efficient method to control the acetylation of chitosan, DAs between 10.6% and 50.6% were reproducibly obtained. In addition to this, MWs of chitosan chains were reduced in a controlled manner in two ways, by ultrasound and by acidic hydrolysis at different temperatures, samples with MWs between 130 kDa and 1300 kDa were obtained. DAs were determined by 1H-NMR and MWs by gel permeation chromatography.
Foamability of Cellulose Palmitate Using Various Physical Blowing Agents in the Extrusion Process
Authors: Rokkonen Teijo , Willberg-Keyriläinen Pia , Ropponen Jarmo , Malm Tero
Published: July 2021

Polymer foams are widely used in several fields such as thermal insulation, acoustics, automotive, and packaging. The most widely used polymer foams are made of polyurethane, polystyrene, and polyethylene but environmental awareness is boosting interest towards alternative bio-based materials. In this study, the suitability of bio-based thermoplastic cellulose palmitate for extrusion foaming was studied. Isobutane, carbon dioxide (CO2), and nitrogen (N2) were tested as blowing agents in different concentrations. Each of them enabled cellulose palmitate foam formation. Isobutane foams exhibited the lowest density with the largest average cell size and nitrogen foams indicated most uniform cell morphology. The effect of die temperature on foamability was further studied with isobutane (3 wt%) as a blowing agent. Die temperature had a relatively low impact on foam density and the differences were mainly encountered with regard to surface quality and cell size distribution. This study demonstrates that cellulose palmitate can be foamed but to produce foams with greater quality, the material homogeneity needs to be improved and researched further.
Effect of Electrosynthesis Potential on Nucleation, Growth, Adhesion, and Electronic Properties of Polypyrrole Thin Films on Fluorine-Doped Tin Oxide (FTO)
Authors: Puerres Jhon , Ortiz Pablo , Cortés María T.
Published: July 2021

Polypyrrole (PPy) is one of the most attractive conducting polymers for thin film applications due to its good electrical conductivity, stability, optical properties, and biocompatibility. Among the technologies in which PPy has gained prominence are optoelectronics and solar energy conversion, where transparent electrodes such as fluorine-doped tin oxide (FTO) or indium tin oxide (ITO) are frequently used. However, FTO substrates have the notable advantage that their components are widely available in nature, unlike those of ITO. Recognizing the importance that the FTO/polypyrrole system has gained in various applications, here, we studied for the first time the nucleation and growth mechanism of electro-synthesized PPy on FTO. Additionally, the effect of the synthesis potential (0.9, 1.0, 1.1, and 1.2 V vs. Ag/AgCl) on the homogeneity, adhesion, conductivity, and HOMO energy levels of PPy films was determined. From current–time transients and scanning electron microscopy, it was found that films synthesized at 0.9 and 1.0 V exhibit 3D growth with progressive nucleation (as well as lower homogeneity and higher adhesion to FTO). In contrast, films synthesized at 1.1 and 1.2 V follow 2D growth with instantaneous nucleation. It was also evident that increasing the polymerization potential leads to polymers with lower conductivity and more negative HOMO levels (versus vacuum). These findings are relevant to encourage the use of electro-synthesized PPy in thin film applications that require a high control of material properties.
Development and Analysis of the Physicochemical and Mechanical Properties of Diorite-Reinforced Epoxy Composites
Authors: Bekeshev Amirbek , Mostovoy Anton , Kadykova Yulia , Akhmetova Marzhan , Tastanova Lyazzat , Lopukhova Marina
Published: July 2021

The aim of this paper is to study the effect of a polyfunctional modifier oligo (resorcinol phenyl phosphate) with terminal phenyl groups and a dispersed mineral filler, diorite, on the physicochemical and deformation-strength properties of epoxy-based composites. The efficiency of using diorite as an active filler of an epoxy polymer, ensuring an increase in strength and a change in the physicochemical properties of epoxy composites, has been proven. We selected the optimal content of diorite both as a structuring additive and as a filler in the composition of the epoxy composite (0.1 and 50 parts by mass), at which diorite reinforces the epoxy composite. It has been found that the addition of diorite into the epoxy composite results in an increase in the Vicat heat resistance from 132 to 140–188 °C and increases the thermal stability of the epoxy composite, which is observed in a shift of the initial destruction temperature to higher temperatures. Furthermore, during the thermal destruction of the composite, the yield of carbonized structures increases (from 54 to 70–77% of the mass), preventing the release of volatile pyrolysis products into the gas phase, which leads to a decrease in the flammability of the epoxy composite. The efficiency of the functionalization of the diorite surface with APTES has been proven, which ensures chemical interaction at the polymer matrix/filler interface and also prevents the aggregation of diorite particles, which, in general, provides an increase in the strength characteristics of epoxy-based composite materials by 10–48%.
Comprehensive Characterization of Polymeric Composites Reinforced with Silica Microparticles Using Leftover Materials of Fused Filament Fabrication 3D Printing
Authors: Ahmed Waleed , Siraj Sidra , Al-Marzouqi Ali H.
Published: July 2021

Silica exhibits properties such that its addition into polymeric materials can result in an enhanced overall quality and improved characteristics and as a result silica has been widely used as a filler material for improving the rheological properties of polymeric materials. The usage of polymers in three-dimensional printing technology has grown exponentially, which has increased the amount of waste produced during this process. Several polymers, such as polypropylene (PP), polyvinyl alcohol (PVA), polylactic acid (PLA), and nylon, are applied in this emerging technology. In this study, the effect of the addition of silica as a filler on the mechanical, thermal, and bulk density properties of the composites prepared from the aforementioned polymeric waste was studied. In addition, the morphology of the composite materials was characterized via scanning electron microscopy. The composite samples were prepared with various silica concentrations using a twin extruder followed by hot compression. Generally, the addition of silica increased the tensile strength of the polymers. For instance, the tensile strength of PVA with 5 wt% filler increased by 76 MPa, whereas those of PP and PLA with 10 wt% filler increased by 7.15 and 121.03 MPa, respectively. The crystallinity of the prepared composite samples ranged from 14% to 35%, which is expected in a composite system. Morphological analysis revealed the random dispersion of silica particles and agglomerate formation at high silica concentrations. The bulk density of the samples decreased with increased amount of filler addition. The addition of silica influenced the changes in the characteristics of the polymeric materials. Furthermore, the properties presented in this study can be used to further study the engineering design, transportation, and production processes, promoting the recycling and reuse of such waste in the same technology with the desired properties.
Aluminum-Free Steelmaking: Desulfurization and Nonmetallic Inclusion Evolution of Si-Killed Steel in Contact with CaO-SiO2-CaF2-MgO Slag
Authors: Piva Stephano P. T. , Pistorius Petrus Christiaan
Published: July 2021

In some applications, deep desulfurization and deoxidation of steels without the use of aluminum are required, using Si as a deoxidant instead, with double-saturated slags in the CaO-SiO2-CaF2-MgO system. This work studied the desulfurization and nonmetallic inclusion evolution for the system using an induction furnace and compared the results with FactSage kinetic simulations. Steel samples were taken from the steel melt and analyzed with ICP-MS and combustion analysis for chemistry, and SEM/EDS for nonmetallic inclusion quantity, size, and composition. The results indicate that the steel was deeply desulfurized, with a final sulfur partition coefficient of 580; MgO was reduced from the slag, yielding dissolved [Mg] that transformed liquid Mn–silicate inclusions into forsterite and MgO. Intentional reoxidation of the melt with oxidized electrolytic iron demonstrated a significant concentration of dissolved [Mg] in the steel, by the formation of additional forsterite and MgO upon reoxidation.
Influence of Blade Thickness on Solid–Liquid Two-Phase Flow and Impeller Wear in a Ceramic Centrifugal Slurry Pump
Authors: Tao Yi , Bai Yongming , Wu Yingchun
Published: July 2021

The impeller blades of ceramic slurry pumps are usually very thick for the purpose of prolonging the service life. In this paper, numerical simulations and wear test were conducted to investigate the influence of blade thickness on the solid–liquid two-phase flow and impeller wear in a ceramic centrifugal slurry pump. The wear test was conducted for CFD validation. The numerical results show that the incident angles of solid particles increase with increasing blade thickness, which results in larger wrap angles of the solid particle trajectories. The increasing wrap angles of the solid particle trajectories offset the region that the collisions between the blade pressure side and the solid particles side take place towards the impeller exit and lead to more impacts between the solid particles and the blade suction side. The numerical results are in good accordance with the wear pattern of the tested impellers, which demonstrates that the numerical method adopted in this paper is predictable in the abrasion of the impeller of a ceramic centrifugal slurry pump. The experimental results show that an increase in the blade thickness alleviates the abrasion of the leading edges and the pressure side of the impeller blades; however, it also aggravates the abrasion of the blade suction side and decreases the pump performance.
Christian Saints in Russian Incantations
Authors: Yudin Aleksey
Published: July 2021

This article discusses the Christian saints who are most often mentioned in Russian incantations: Sts. George, Nicholas, Florus and Laurus, Kossma and Damian, Zosima and Savvaty of Solovki, as well as the semi-apocryphal saints Sisinius and Solomonia. The first six are among the most popular saints of Russian folk Orthodoxy. The article presents the naming conventions of saints, and their attributes and functions in Russian folk magic. Depending on their magical function, the protagonists of the incantations can act as helpers, protectors, and healers. They assist in various practical areas of life, and protect against real and magical dangers, in addition to helping healing from diseases and wounds.
Unapologetic Apologetics: Julius Wellhausen, Anti-Judaism, and Hebrew Bible Scholarship
Authors: Davis Stacy
Published: July 2021

Julius Wellhausen (1844–1918) is in many ways the ancestor of modern Hebrew Bible scholarship. His Prolegomena to the History of Israel condensed decades of source critical work on the Torah into a documentary hypothesis that is still taught today in almost all Hebrew Bible courses in some form. What is not taught as frequently is the anti-Judaism that underpins his hypothesis. This is in part due to unapologetic apologetics regarding Wellhausen’s bias, combined with the insistence that a nineteenth-century scholar cannot be judged by twenty-first century standards. These calls for compassion are made exclusively by white male scholars, leaving Jewish scholars the solitary task of pointing out Wellhausen’s clear anti-Judaism. In a discipline that is already overwhelmingly white, male and Christian, the minimizing of Wellhausen’s racism suggests two things. First, those who may criticize contextual biblical studies done by women and scholars of color have no problem pleading for a contextual understanding of Wellhausen while downplaying the growing anti-Judaism and nationalism that was a part of nineteenth-century Germany. Second, recent calls for inclusion in the Society of Biblical Literature may be well intentioned but ultimately useless if the guild cannot simply call one of its most brilliant founders the biased man that he was.
Sufism and the Sacred Feminine in Lombok, Indonesia: Situating Spirit Queen Dewi Anjani and Female Saints in Nahdlatul Wathan
Authors: Smith Bianca J.
Published: July 2021

This article is a feminist ethnographic exploration of how ‘indigenous’ notions of a ‘sacred feminine’ shape Sufi praxis on the island of Lombok in the eastern part of Indonesia in Southeast Asia. I demonstrate through long-term immersive anthropological fieldwork how in her indigenous form as Dewi Anjani ‘Spirit Queen of Jinn’ and as ‘Holy Saint of Allah’ who rules Lombok from Mount Rinjani, together with a living female saint and Murshida with whom she shares sacred kinship, these feminine beings shape the kind of Sufi praxis that has formed in the largest local Islamic organization in Lombok, Nahdlatul Wathan, and its Sufi order, Hizib Nahdlatul Wathan. Arguments are situated in a Sufi feminist standpoint, revealing how an active integration of indigeneity into understandings of mystical experience gives meaning to the sacred feminine in aspects of Sufi praxis in both complementary and hierarchical ways without challenging Islamic gender constructs that reproduce patriarchal expressions of Sufism and Islam.
“Client Transformation”: Spiritual and Non-Spiritual Outcomes for Social Service Recipients of Evangelical Faith-Based Organisations
Authors: Gokani Ravi
Published: July 2021

This brief paper outlines the various ways that Canadian Evangelical faith-based organisations in Southern Ontario effect “client transformation”. Data from qualitative interviews, focus groups, and surveys administered to clients and providers in faith-based organizations yielded two types of outcomes—spiritual and non-spiritual. Regarding the latter, I suggest two sub-types of non-spiritual outcomes: (a) socio-behavioural and (b) psycho-affective changes. I also suggest three major types of spiritual outcomes: (a) growing in Christianity, (b) warming to Christianity, and (c) accepting Christianity. I conclude with a discussion about implications and limitations of the study for the scholarship on faith-based organizations.
Relationship between Fire Events and Land Use Changes in the State of São Paulo, Brazil
Authors: Philogene Sheena , Ni-Meister Wenge
Published: July 2021

This study investigated the land use and land cover changes in the state of São Paulo, Brazil, for the period of 2002 through 2017, to determine if forested areas were burned or converted to other land uses, to analyze the use of fire as a catalyst and mechanism for land cover change, and to determine if there was a relationship between land use changes and gross domestic product (GDP). MapBiomas classifications and MODIS data were analyzed using the Google Earth Engine. The results of the analysis found that there were minimal changes in the forested areas in São Paulo during the study period; however, there was a 5% increase in natural forest and a 75% increase in planted forest cover. On the other hand, there was a 128% increase in sugarcane, and nearly a 50% decrease in pasture land coverage, suggesting that land was converted from pasture to more profitable agricultural land. Finally, there was a strong positive correlation (r = 0.96) between the increase in sugarcane and the GDP, and a negative correlation between the frequency of fire events and economic production (r = −0.62). Overall, there was a decline in fire events in São Paulo, with fire events occurring in less than 2% of the total observed land area by 2017. This overall declining trend in fire events are likely the direct result of increases in green harvest methods, which prevent the need for pre-harvest burning.
Improved Rainfall Data in the Philippines through Concurrent Use of GPM IMERG and Ground-Based Measurements
Authors: Veloria Archie , Perez Gay Jane , Tapang Giovanni , Comiso Josefino
Published: July 2021

The availability of accurate and reliable rainfall data that are applicable to various phenomenological, climatological, and modeling studies is important, especially in the Philippines, which is considered to be highly vulnerable to natural hazards and a changing climate. The presented strategy involved constructing a dataset consisting of synoptic data, automatic rain gauge (ARG) measurements, and satellite data that are co-registered, consistent, and formatted in the same manner. Although sparse in number, the synoptic stations provide the most accurate rainfall information and were used as the baseline for creating the dataset. The ARGs that are within a distance of 1 km to the synoptic stations were used to determine the correction factors needed to make the synoptic and ARG data consistent. Subsequently, the corrected ARGs were used to make the satellite IMERG data consistent with both ARG and synoptic data. In case of the latter, only IMERG pixels with at least 10 ARGs within the relatively large footprint of the satellite sensor were used in estimating the required correction parameters derived from a combination of a power transform and linear regression correction techniques. The final results show good agreement of synoptic and corrected ARG data with correlation coefficients of 0.94 and 0.97 for the 10 day and monthly data, respectively, and improvement in the linear regression slope from 0.67 to 0.90 for 10 day data, and 0.70 to 0.94 for monthly data. In addition, the corrected ARG data agree well with the corrected IMERG data, with correlation coefficients of 0.88 and 0.93 for the 10 day and monthly data, respectively, and an improvement in slope from 0.66 to 0.87 for 10 day data, and 0.74 to 0.99 for monthly data. The merit of using a combined dataset is illustrated through comparative analyses of the IMERG data and spatially interpolated synoptic and ARG data. The results show general agreements in spatial patterns of rainfall across the datasets, especially in areas where in situ measurements are recorded. The observed discrepancy when ground data is limited emphasizes the need for satellite IMERG data to obtain the true spatial patterns of rainfall distribution.
Editorial for the Special Issue “Advanced Artificial Intelligence and Deep Learning for Remote Sensing”
Authors: Jeon Gwanggil
Published: July 2021

Remote sensing is a fundamental tool for comprehending the earth and supporting human–earth communications [...]
Sino–EU Earth Observation Data to Support the Monitoring and Management of Agricultural Resources
Authors: Pignatti Stefano , Casa Raffaele , Laneve Giovanni , Li Zhenhai , Liu Linyi , Marzialetti Pablo , Mzid Nada , Pascucci Simone , Silvestro Paolo Cosmo , Tolomio Massimo , Upreti Deepak , Yang Hao , Yang Guijun , Huang Wenjiang
Published: July 2021

Novel approaches and algorithms to estimate crop physiological processes from Earth Observation (EO) data are essential to develop more sustainable management practices in agricultural systems. Within this context, this paper presents the results of different research activities carried out within the ESA-MOST Dragon 4 programme. The paper encompasses two research avenues: (a) the retrieval of biophysical variables of crops and yield prediction; and (b) food security related to different crop management strategies. Concerning the retrieval of variables, results show that LAI, derived by radiative transfer model (RTM) inversion, when assimilated into a crop growth model (i.e., SAFY) provides a way to assess yields with a higher accuracy with respect to open loop model runs: 1.14 t·ha−1 vs 4.42 t·ha−1 RMSE for assimilation and open loop, respectively. Concerning food security, results show that different pathogens could be detected by remote sensing satellite data. A k coefficient higher than 0.84 was achieved for yellow rust, thus assuring a monitoring accuracy, and for the diseased samples k was higher than 0.87. Concerning permanent crops, neural network (NN) algorithms allow classification of the Pseudomonas syringae pathogen on kiwi orchards with an overall accuracy higher than 91%.
Supercooled Liquid Water Detection Capabilities from Ka-Band Doppler Profiling Radars: Moment-Based Algorithm Formulation and Assessment
Authors: Kalogeras Petros , Battaglia Alessandro , Kollias Pavlos
Published: July 2021

The occurrence of supercooled liquid water in mixed-phase cloud (MPC) affects their cloud microphysical and radiative properties. The prevalence of MPCs in the mid- and high latitudes translates these effects to significant contributions to Earth’s radiative balance and hydrological cycle. The current study develops and assesses a radar-only, moment-based phase partition technique for the demarcation of supercooled liquid water volumes in arctic, MPC conditions. The study utilizes observations from the Ka band profiling radar, the collocated high spectral resolution lidar, and ambient temperature profiles from radio sounding deployments following a statistical analysis of 5.5 years of data (January 2014–May 2019) from the Atmospheric Radiation Measurement observatory at the North Slope of Alaska. The ice/liquid phase partition occurs via a per-pixel, neighborhood-dependent algorithm based on the premise that the partitioning can be deduced by examining the mean values of locally sampled probability distributions of radar-based observables and then compare those against the means of climatologically derived, per-phase probability distributions. Analyzed radar observables include linear depolarization ratio (LDR), spectral width, and vertical gradients of reflectivity factor and radial velocity corrected for vertical air motion. Results highlight that the optimal supercooled liquid water detection skill levels are realized for the radar variable combination of spectral width and reflectivity vertical gradient, suggesting that radar-based polarimetry, in the absence of full LDR spectra, is not as critical as Doppler capabilities. The cloud phase masking technique is proven particularly reliable when applied to cloud tops with an Equitable Threat Score (ETS) of 65%; the detection of embedded supercooled layers remains much more uncertain (ETS = 27%).
Large-Scale River Mapping Using Contrastive Learning and Multi-Source Satellite Imagery
Authors: Wei Zhihao , Jia Kebin , Liu Pengyu , Jia Xiaowei , Xie Yiqun , Jiang Zhe
Published: July 2021

River system is critical for the future sustainability of our planet but is always under the pressure of food, water and energy demands. Recent advances in machine learning bring a great potential for automatic river mapping using satellite imagery. Surface river mapping can provide accurate and timely water extent information that is highly valuable for solid policy and management decisions. However, accurate large-scale river mapping remains challenging given limited labels, spatial heterogeneity and noise in satellite imagery (e.g., clouds and aerosols). In this paper, we propose a new multi-source data-driven method for large-scale river mapping by combining multi-spectral imagery and synthetic aperture radar data. In particular, we build a multi-source data segmentation model, which uses contrastive learning to extract the common information between multiple data sources while also preserving distinct knowledge from each data source. Moreover, we create the first large-scale multi-source river imagery dataset based on Sentinel-1 and Sentinel-2 satellite data, along with 1013 handmade accurate river segmentation mask (which will be released to the public). In this dataset, our method has been shown to produce superior performance (F1-score is 91.53%) over multiple state-of-the-art segmentation algorithms. We also demonstrate the effectiveness of the proposed contrastive learning model in mapping river extent when we have limited and noisy data.
A New Method for Automatic Extraction and Analysis of Discontinuities Based on TIN on Rock Mass Surfaces
Authors: Wu Xiang , Wang Fengyan , Wang Mingchang , Zhang Xuqing , Wang Qing , Zhang Shuo
Published: July 2021

Light detection and ranging (LiDAR) can quickly and accurately obtain 3D point clouds on the surface of rock masses, and on the basis of this, discontinuity information can be extracted automatically. This paper proposes a new method to automatically extract discontinuity information from 3D point clouds on the surface of rock masses. This method first applies the improved K-means algorithm based on the clustering algorithm by fast search and find of density peaks (DPCA) and the silhouette coefficient in the cluster validity index to identify the discontinuity sets of rock masses, and then uses the hierarchical density-based spatial clustering of applications with noise (HDBSCAN) algorithm to segment the discontinuity sets and to extract each discontinuity from a discontinuity set. Finally, the random sampling consistency (RANSAC) method is used to fit the discontinuities and to calculate their parameters. The 3D point clouds of the typical rock slope in the Rockbench repository is used to extract the discontinuity orientations using the new method, and these are compared with the results obtained from the classical approach and the previous automatic methods. The results show that, compared to the results obtained by Riquelme et al. in 2014, the average deviation of the dip direction and dip angle is reduced by 26% and 8%, respectively; compared to the results obtained by Chen et al. in 2016, the average deviation of the dip direction and dip angle is reduced by 39% and 40%, respectively. The method is also applied to an artificial quarry slope, and the average deviation of the dip direction and dip angle is 5.3° and 4.8°, respectively, as compared to the manual method. Furthermore, the related parameters are analyzed. The study shows that the new method is reliable, has a higher precision when identifying rock mass discontinuities, and can be applied to practical engineering.
Integration of a Dielectrophoretic Tapered Aluminum Microelectrode Array with a Flow Focusing Technique
Authors: Rashid Naqib Fuad Abd , Deivasigamani Revathy , Wee M. F. Mohd Razip , Hamzah Azrul Azlan , Buyong Muhamad Ramdzan
Published: July 2021

We present the integration of a flow focusing microfluidic device in a dielectrophoretic application that based on a tapered aluminum microelectrode array (TAMA). The characterization and optimization method of microfluidic geometry performs the hydrodynamic flow focusing on the channel. The sample fluids are hydrodynamically focused into the region of interest (ROI) where the dielectrophoresis force (FDEP) is dominant. The device geometry is designed using 3D CAD software and fabricated using the micro-milling process combined with soft lithography using PDMS. The flow simulation is achieved using COMSOL Multiphysics 5.5 to study the effect of the flow rate ratio between the sample fluids (Q1) and the sheath fluids (Q2) toward the width of flow focusing. Five different flow rate ratios (Q1/Q2) are recorded in this experiment, which are 0.2, 0.4, 0.6, 0.8 and 1.0. The width of flow focusing is increased linearly with the flow rate ratio (Q1/Q2) for both the simulation and the experiment. At the highest flow rate ratio (Q1/Q2 = 1), the width of flow focusing is obtained at 638.66 µm and at the lowest flow rate ratio (Q1/Q2 = 0.2), the width of flow focusing is obtained at 226.03 µm. As a result, the flow focusing effect is able to reduce the dispersion of the particles in the microelectrode from 2000 µm to 226.03 µm toward the ROI. The significance of flow focusing on the separation of particles is studied using 10 and 1 µm polystyrene beads by applying a non-uniform electrical field to the TAMA at 10 VPP, 150 kHz. Ultimately, we are able to manipulate the trajectories of two different types of particles in the channel. For further validation, the focusing of 3.2 µm polystyrene beads within the dominant FDEP results in an enhanced manipulation efficiency from 20% to 80% in the ROI.
Fabry–Perot Resonance in 2D Dielectric Grating for Figure of Merit Enhancement in Refractive Index Sensing
Authors: Pechprasarn Suejit , Sasivimolkul Suvicha , Suvarnaphaet Phitsini
Published: July 2021

We have recently reported in our previous work that one-dimensional dielectric grating can provide an open structure for Fabry–Perot mode excitation. The grating gaps allow the sample refractive index to fill up the grating spaces enabling the sample to perturb the Fabry–Perot mode resonant condition. Thus, the grating structure can be utilized as a refractive index sensor and provides convenient sample access from the open end of the grating with an enhanced figure of merit compared to the other thin-film technologies. Here, we demonstrate that 2D grating structures, such as rectangular pillars and circular pillars, can further enhance refractive index sensing performance. The refractive index theory for rectangular pillars and circular pillars are proposed and validated with rigorous coupled wave theory. An effective refractive index theory is proposed to simplify the 2D grating computation and accurately predict the Fabry–Perot mode positions. The 2D gratings have more grating space leading to a higher resonant condition perturbation and sensitivity. They also provide narrower Fabry–Perot mode reflectance dips leading to a 4.5 times figure of merit enhancement than the Fabry–Perot modes excited in the 1D grating. The performance comparison for thin-film technologies for refractive index sensing is also presented and discussed.
The Use of Wearable Sensor Technology to Detect Shock Impacts in Sports and Occupational Settings: A Scoping Review
Authors: Eitzen Ingrid , Renberg Julie , Færevik Hilde
Published: July 2021

Shock impacts during activity may cause damage to the joints, muscles, bones, or inner organs. To define thresholds for tolerable impacts, there is a need for methods that can accurately monitor shock impacts in real-life settings. Therefore, the main aim of this scoping review was to present an overview of existing methods for assessments of shock impacts using wearable sensor technology within two domains: sports and occupational settings. Online databases were used to identify papers published in 2010–2020, from which we selected 34 papers that used wearable sensor technology to measure shock impacts. No studies were found on occupational settings. For the sports domain, accelerometry was the dominant type of wearable sensor technology utilized, interpreting peak acceleration as a proxy for impact. Of the included studies, 28 assessed foot strike in running, head impacts in invasion and team sports, or different forms of jump landings or plyometric movements. The included studies revealed a lack of consensus regarding sensor placement and interpretation of the results. Furthermore, the identified high proportion of validation studies support previous concerns that wearable sensors at present are inadequate as a stand-alone method for valid and accurate data on shock impacts in the field.
An Analytic Model for Reducing Authentication Signaling Traffic in an End-to-End Authentication Scheme
Authors: Nashwan Shadi , Nashwan Imad I. H.
Published: July 2021

In an end-to-end authentication (E2EA) scheme, the physician, patient, and sensor nodes authenticate each other through the healthcare service provider in three phases: the long-term authentication phase (LAP), short-term authentication phase (SAP), and sensor authentication phase (WAP). Once the LAP is executed between all communication nodes, the SAP is executed (m) times between the physician and patient by deriving a new key from the PSij key generated by healthcare service provider during the LAP. In addition, the WAP is executed between the connected sensor and patient (m + 1) times without going back to the service provider. Thus, it is critical to determine an appropriate (m) value to maintain a specific security level and to minimize the cost of E2EA. Therefore, we proposed an analytic model in which the authentication signaling traffic is represented by a Poisson process to derive an authentication signaling traffic cost function for the (m) value. wherein the residence time of authentication has three distributions: gamma, hypo-exponential, and exponential. Finally, using the numerical analysis of the derived cost function, an optimal value (m) that minimizes the authentication signaling traffic cost of the E2EA scheme was determined.